data_8W2S
# 
_entry.id   8W2S 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8W2S         pdb_00008w2s 10.2210/pdb8w2s/pdb 
WWPDB D_1000281737 ?            ?                   
EMDB  EMD-43757    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1  'Structure model' 1 0 2025-01-15 ? 
2  'EM metadata'     1 0 2025-01-15 ? 
3  'Additional map'  1 0 2025-01-15 ? 
4  FSC               1 0 2025-01-15 ? 
5  'Half map'        1 0 2025-01-15 1 
6  'Half map'        1 0 2025-01-15 2 
7  Image             1 0 2025-01-15 ? 
8  'Primary map'     1 0 2025-01-15 ? 
9  'Structure model' 1 1 2025-06-04 ? 
10 'EM metadata'     1 1 2025-06-04 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1 1 'Structure model' repository 'Initial release' ? ? 
2 2 'EM metadata'     repository 'Initial release' ? ? 
3 3 'Additional map'  repository 'Initial release' ? ? 
4 4 FSC               repository 'Initial release' ? ? 
5 5 'Half map'        repository 'Initial release' ? ? 
6 6 'Half map'        repository 'Initial release' ? ? 
7 7 Image             repository 'Initial release' ? ? 
8 8 'Primary map'     repository 'Initial release' ? ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 9  'Structure model' 'Data collection'      
2 10 'EM metadata'     'Data processing'      
3 10 'EM metadata'     'Experimental summary' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 9  'Structure model' em_admin    
2 9  'Structure model' em_software 
3 10 'EM metadata'     em_admin    
4 10 'EM metadata'     em_software 
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1 9  'Structure model' '_em_admin.last_update' 
2 9  'Structure model' '_em_software.name'     
3 10 'EM metadata'     '_em_admin.last_update' 
4 10 'EM metadata'     '_em_software.name'     
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8W2S 
_pdbx_database_status.recvd_initial_deposition_date   2024-02-21 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        
'An intricately folded guide RNA scaffold enables DNA targeting by the compact Cas9d nuclease' 
_pdbx_database_related.db_id          EMD-43757 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              dtaylor@utexas.edu 
_pdbx_contact_author.name_first         David 
_pdbx_contact_author.name_last          Taylor 
_pdbx_contact_author.name_mi            W 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-6198-1194 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Fregoso Ocampo, R.' 1 0009-0006-0951-8975 
'Bravo, J.P.K.'      2 0000-0003-0456-0753 
'Taylor, D.W.'       3 0000-0002-6198-1194 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Nat Commun' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2041-1723 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            16 
_citation.language                  ? 
_citation.page_first                457 
_citation.page_last                 457 
_citation.title                     'DNA targeting by compact Cas9d and its resurrected ancestor.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1038/s41467-024-55573-4 
_citation.pdbx_database_id_PubMed   39774105 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Ocampo, R.F.'      1  ?                   
primary 'Bravo, J.P.K.'     2  0000-0003-0456-0753 
primary 'Dangerfield, T.L.' 3  0000-0003-1413-2082 
primary 'Nocedal, I.'       4  ?                   
primary 'Jirde, S.A.'       5  ?                   
primary 'Alexander, L.M.'   6  0000-0003-0152-4554 
primary 'Thomas, N.C.'      7  ?                   
primary 'Das, A.'           8  ?                   
primary 'Nielson, S.'       9  ?                   
primary 'Johnson, K.A.'     10 ?                   
primary 'Brown, C.T.'       11 0000-0002-7758-6447 
primary 'Butterfield, C.N.' 12 ?                   
primary 'Goltsman, D.S.A.'  13 ?                   
primary 'Taylor, D.W.'      14 0000-0002-6198-1194 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer man 'HNH nuclease domain-containing protein' 108989.773 1 ? ? ? ? 
2 polymer man sgRNA                                    50836.031  1 ? ? ? ? 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)'   no no 
;MERELVLGIDYGGKYTGLAVVDRRHNQVLYANRLKMRDDVAGILKDRRKQRGIRRTAQTKKKRLRELKNYLKSIGYNEST
ATFETVYSLAHKRGYDYADMPEEKTSEEIEAMDVEERKQWEKEKQEWEETKRNSRHRKEVVKDVHKAMIEGRATEEQIKR
VERIFNKQYRPKRFNNRILTKCKVEDCGVNTPLRKNVRDLLIENIVRFFPIEQSEKDNLKDAVLDKNRREEVKSFFRKHK
TDEHIRKQVYDIADNKLSGRTVFCKEHILEHTEHSKEERKVFRLAPSLKTKIENVLAVIKDEILPKFTVNKVVMESNNFD
IAAKTQGKKRLAKEEYGKGPREGKETRKEALLRETDGRCIYCGKSIDISNAHDDHIFPRKAGGLNIFANLVACCAVCNEN
KKGRTPLESGISPKPEIIAFMKNDLKKKILEDARNINTVDFNKYMSHASIGWRYMRDRLRESAGNKKLPIERQSGIYTAY
FRRWWGFKKERGNTLHHALDAVILASRKGYSDDGLVDMTLKPKYNKGGEFDPEKHLPEPIEFKMDKGSRGSALHDRNPLS
YKKGIITRRFMVTEIECGKEDDVISETYREKLKEAFKRFDTKKGKCLTDKEAKEAGFCIKKNELVMSLKCSIKGTGPGQM
IRINNNVFKTNVHNVGVDVYLDEKGKKKAYERKNPRLSKHFIEPPPQPNGRVSFTLKRRDMVTVEGEDAIYRIKKLGTSP
TIEAVVGSDGKTRTVSATKLTKANSAEIEQSEKDNLKDAVLDKNRREEVKSFFRKHKTDEHIRKQVYDIADNKLSGRTVF
CKEHILSRGSALHDRNPLSYKKGIITRRFMVTEIECGKEDDVISETYREKLKEAFKRFDTKKGKCLTDKEAKEAGFCIKK
NELVMSLKCSIKGTGPGQMIRINNNVFKTNVHNV(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)
(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)RKNPRLSKHFIE
;
;MERELVLGIDYGGKYTGLAVVDRRHNQVLYANRLKMRDDVAGILKDRRKQRGIRRTAQTKKKRLRELKNYLKSIGYNEST
ATFETVYSLAHKRGYDYADMPEEKTSEEIEAMDVEERKQWEKEKQEWEETKRNSRHRKEVVKDVHKAMIEGRATEEQIKR
VERIFNKQYRPKRFNNRILTKCKVEDCGVNTPLRKNVRDLLIENIVRFFPIEQSEKDNLKDAVLDKNRREEVKSFFRKHK
TDEHIRKQVYDIADNKLSGRTVFCKEHILEHTEHSKEERKVFRLAPSLKTKIENVLAVIKDEILPKFTVNKVVMESNNFD
IAAKTQGKKRLAKEEYGKGPREGKETRKEALLRETDGRCIYCGKSIDISNAHDDHIFPRKAGGLNIFANLVACCAVCNEN
KKGRTPLESGISPKPEIIAFMKNDLKKKILEDARNINTVDFNKYMSHASIGWRYMRDRLRESAGNKKLPIERQSGIYTAY
FRRWWGFKKERGNTLHHALDAVILASRKGYSDDGLVDMTLKPKYNKGGEFDPEKHLPEPIEFKMDKGSRGSALHDRNPLS
YKKGIITRRFMVTEIECGKEDDVISETYREKLKEAFKRFDTKKGKCLTDKEAKEAGFCIKKNELVMSLKCSIKGTGPGQM
IRINNNVFKTNVHNVGVDVYLDEKGKKKAYERKNPRLSKHFIEPPPQPNGRVSFTLKRRDMVTVEGEDAIYRIKKLGTSP
TIEAVVGSDGKTRTVSATKLTKANSAEIEQSEKDNLKDAVLDKNRREEVKSFFRKHKTDEHIRKQVYDIADNKLSGRTVF
CKEHILSRGSALHDRNPLSYKKGIITRRFMVTEIECGKEDDVISETYREKLKEAFKRFDTKKGKCLTDKEAKEAGFCIKK
NELVMSLKCSIKGTGPGQMIRINNNVFKTNVHNVXXXXXXXXXXXXXXXXRKNPRLSKHFIE
;
A ? 
2 polyribonucleotide no no 
;GACGCAUAAAGAUGAGACGCGUUACAGUUAAGGCUCUGAAAAGAGCCUUAAUUGUAAAACGCCUAUACAGUGAAGGGAUA
UACGCUUGGGUUUGUCCAGCCUGAGCCUCUAUGCCAGAAAUGGCGCCUUCAUCGUGGGUUAGGACAUUUAAUUUUUUU
;
;GACGCAUAAAGAUGAGACGCGUUACAGUUAAGGCUCUGAAAAGAGCCUUAAUUGUAAAACGCCUAUACAGUGAAGGGAUA
UACGCUUGGGUUUGUCCAGCCUGAGCCUCUAUGCCAGAAAUGGCGCCUUCAUCGUGGGUUAGGACAUUUAAUUUUUUU
;
B ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   GLU n 
1 3   ARG n 
1 4   GLU n 
1 5   LEU n 
1 6   VAL n 
1 7   LEU n 
1 8   GLY n 
1 9   ILE n 
1 10  ASP n 
1 11  TYR n 
1 12  GLY n 
1 13  GLY n 
1 14  LYS n 
1 15  TYR n 
1 16  THR n 
1 17  GLY n 
1 18  LEU n 
1 19  ALA n 
1 20  VAL n 
1 21  VAL n 
1 22  ASP n 
1 23  ARG n 
1 24  ARG n 
1 25  HIS n 
1 26  ASN n 
1 27  GLN n 
1 28  VAL n 
1 29  LEU n 
1 30  TYR n 
1 31  ALA n 
1 32  ASN n 
1 33  ARG n 
1 34  LEU n 
1 35  LYS n 
1 36  MET n 
1 37  ARG n 
1 38  ASP n 
1 39  ASP n 
1 40  VAL n 
1 41  ALA n 
1 42  GLY n 
1 43  ILE n 
1 44  LEU n 
1 45  LYS n 
1 46  ASP n 
1 47  ARG n 
1 48  ARG n 
1 49  LYS n 
1 50  GLN n 
1 51  ARG n 
1 52  GLY n 
1 53  ILE n 
1 54  ARG n 
1 55  ARG n 
1 56  THR n 
1 57  ALA n 
1 58  GLN n 
1 59  THR n 
1 60  LYS n 
1 61  LYS n 
1 62  LYS n 
1 63  ARG n 
1 64  LEU n 
1 65  ARG n 
1 66  GLU n 
1 67  LEU n 
1 68  LYS n 
1 69  ASN n 
1 70  TYR n 
1 71  LEU n 
1 72  LYS n 
1 73  SER n 
1 74  ILE n 
1 75  GLY n 
1 76  TYR n 
1 77  ASN n 
1 78  GLU n 
1 79  SER n 
1 80  THR n 
1 81  ALA n 
1 82  THR n 
1 83  PHE n 
1 84  GLU n 
1 85  THR n 
1 86  VAL n 
1 87  TYR n 
1 88  SER n 
1 89  LEU n 
1 90  ALA n 
1 91  HIS n 
1 92  LYS n 
1 93  ARG n 
1 94  GLY n 
1 95  TYR n 
1 96  ASP n 
1 97  TYR n 
1 98  ALA n 
1 99  ASP n 
1 100 MET n 
1 101 PRO n 
1 102 GLU n 
1 103 GLU n 
1 104 LYS n 
1 105 THR n 
1 106 SER n 
1 107 GLU n 
1 108 GLU n 
1 109 ILE n 
1 110 GLU n 
1 111 ALA n 
1 112 MET n 
1 113 ASP n 
1 114 VAL n 
1 115 GLU n 
1 116 GLU n 
1 117 ARG n 
1 118 LYS n 
1 119 GLN n 
1 120 TRP n 
1 121 GLU n 
1 122 LYS n 
1 123 GLU n 
1 124 LYS n 
1 125 GLN n 
1 126 GLU n 
1 127 TRP n 
1 128 GLU n 
1 129 GLU n 
1 130 THR n 
1 131 LYS n 
1 132 ARG n 
1 133 ASN n 
1 134 SER n 
1 135 ARG n 
1 136 HIS n 
1 137 ARG n 
1 138 LYS n 
1 139 GLU n 
1 140 VAL n 
1 141 VAL n 
1 142 LYS n 
1 143 ASP n 
1 144 VAL n 
1 145 HIS n 
1 146 LYS n 
1 147 ALA n 
1 148 MET n 
1 149 ILE n 
1 150 GLU n 
1 151 GLY n 
1 152 ARG n 
1 153 ALA n 
1 154 THR n 
1 155 GLU n 
1 156 GLU n 
1 157 GLN n 
1 158 ILE n 
1 159 LYS n 
1 160 ARG n 
1 161 VAL n 
1 162 GLU n 
1 163 ARG n 
1 164 ILE n 
1 165 PHE n 
1 166 ASN n 
1 167 LYS n 
1 168 GLN n 
1 169 TYR n 
1 170 ARG n 
1 171 PRO n 
1 172 LYS n 
1 173 ARG n 
1 174 PHE n 
1 175 ASN n 
1 176 ASN n 
1 177 ARG n 
1 178 ILE n 
1 179 LEU n 
1 180 THR n 
1 181 LYS n 
1 182 CYS n 
1 183 LYS n 
1 184 VAL n 
1 185 GLU n 
1 186 ASP n 
1 187 CYS n 
1 188 GLY n 
1 189 VAL n 
1 190 ASN n 
1 191 THR n 
1 192 PRO n 
1 193 LEU n 
1 194 ARG n 
1 195 LYS n 
1 196 ASN n 
1 197 VAL n 
1 198 ARG n 
1 199 ASP n 
1 200 LEU n 
1 201 LEU n 
1 202 ILE n 
1 203 GLU n 
1 204 ASN n 
1 205 ILE n 
1 206 VAL n 
1 207 ARG n 
1 208 PHE n 
1 209 PHE n 
1 210 PRO n 
1 211 ILE n 
1 212 GLU n 
1 213 GLN n 
1 214 SER n 
1 215 GLU n 
1 216 LYS n 
1 217 ASP n 
1 218 ASN n 
1 219 LEU n 
1 220 LYS n 
1 221 ASP n 
1 222 ALA n 
1 223 VAL n 
1 224 LEU n 
1 225 ASP n 
1 226 LYS n 
1 227 ASN n 
1 228 ARG n 
1 229 ARG n 
1 230 GLU n 
1 231 GLU n 
1 232 VAL n 
1 233 LYS n 
1 234 SER n 
1 235 PHE n 
1 236 PHE n 
1 237 ARG n 
1 238 LYS n 
1 239 HIS n 
1 240 LYS n 
1 241 THR n 
1 242 ASP n 
1 243 GLU n 
1 244 HIS n 
1 245 ILE n 
1 246 ARG n 
1 247 LYS n 
1 248 GLN n 
1 249 VAL n 
1 250 TYR n 
1 251 ASP n 
1 252 ILE n 
1 253 ALA n 
1 254 ASP n 
1 255 ASN n 
1 256 LYS n 
1 257 LEU n 
1 258 SER n 
1 259 GLY n 
1 260 ARG n 
1 261 THR n 
1 262 VAL n 
1 263 PHE n 
1 264 CYS n 
1 265 LYS n 
1 266 GLU n 
1 267 HIS n 
1 268 ILE n 
1 269 LEU n 
1 270 GLU n 
1 271 HIS n 
1 272 THR n 
1 273 GLU n 
1 274 HIS n 
1 275 SER n 
1 276 LYS n 
1 277 GLU n 
1 278 GLU n 
1 279 ARG n 
1 280 LYS n 
1 281 VAL n 
1 282 PHE n 
1 283 ARG n 
1 284 LEU n 
1 285 ALA n 
1 286 PRO n 
1 287 SER n 
1 288 LEU n 
1 289 LYS n 
1 290 THR n 
1 291 LYS n 
1 292 ILE n 
1 293 GLU n 
1 294 ASN n 
1 295 VAL n 
1 296 LEU n 
1 297 ALA n 
1 298 VAL n 
1 299 ILE n 
1 300 LYS n 
1 301 ASP n 
1 302 GLU n 
1 303 ILE n 
1 304 LEU n 
1 305 PRO n 
1 306 LYS n 
1 307 PHE n 
1 308 THR n 
1 309 VAL n 
1 310 ASN n 
1 311 LYS n 
1 312 VAL n 
1 313 VAL n 
1 314 MET n 
1 315 GLU n 
1 316 SER n 
1 317 ASN n 
1 318 ASN n 
1 319 PHE n 
1 320 ASP n 
1 321 ILE n 
1 322 ALA n 
1 323 ALA n 
1 324 LYS n 
1 325 THR n 
1 326 GLN n 
1 327 GLY n 
1 328 LYS n 
1 329 LYS n 
1 330 ARG n 
1 331 LEU n 
1 332 ALA n 
1 333 LYS n 
1 334 GLU n 
1 335 GLU n 
1 336 TYR n 
1 337 GLY n 
1 338 LYS n 
1 339 GLY n 
1 340 PRO n 
1 341 ARG n 
1 342 GLU n 
1 343 GLY n 
1 344 LYS n 
1 345 GLU n 
1 346 THR n 
1 347 ARG n 
1 348 LYS n 
1 349 GLU n 
1 350 ALA n 
1 351 LEU n 
1 352 LEU n 
1 353 ARG n 
1 354 GLU n 
1 355 THR n 
1 356 ASP n 
1 357 GLY n 
1 358 ARG n 
1 359 CYS n 
1 360 ILE n 
1 361 TYR n 
1 362 CYS n 
1 363 GLY n 
1 364 LYS n 
1 365 SER n 
1 366 ILE n 
1 367 ASP n 
1 368 ILE n 
1 369 SER n 
1 370 ASN n 
1 371 ALA n 
1 372 HIS n 
1 373 ASP n 
1 374 ASP n 
1 375 HIS n 
1 376 ILE n 
1 377 PHE n 
1 378 PRO n 
1 379 ARG n 
1 380 LYS n 
1 381 ALA n 
1 382 GLY n 
1 383 GLY n 
1 384 LEU n 
1 385 ASN n 
1 386 ILE n 
1 387 PHE n 
1 388 ALA n 
1 389 ASN n 
1 390 LEU n 
1 391 VAL n 
1 392 ALA n 
1 393 CYS n 
1 394 CYS n 
1 395 ALA n 
1 396 VAL n 
1 397 CYS n 
1 398 ASN n 
1 399 GLU n 
1 400 ASN n 
1 401 LYS n 
1 402 LYS n 
1 403 GLY n 
1 404 ARG n 
1 405 THR n 
1 406 PRO n 
1 407 LEU n 
1 408 GLU n 
1 409 SER n 
1 410 GLY n 
1 411 ILE n 
1 412 SER n 
1 413 PRO n 
1 414 LYS n 
1 415 PRO n 
1 416 GLU n 
1 417 ILE n 
1 418 ILE n 
1 419 ALA n 
1 420 PHE n 
1 421 MET n 
1 422 LYS n 
1 423 ASN n 
1 424 ASP n 
1 425 LEU n 
1 426 LYS n 
1 427 LYS n 
1 428 LYS n 
1 429 ILE n 
1 430 LEU n 
1 431 GLU n 
1 432 ASP n 
1 433 ALA n 
1 434 ARG n 
1 435 ASN n 
1 436 ILE n 
1 437 ASN n 
1 438 THR n 
1 439 VAL n 
1 440 ASP n 
1 441 PHE n 
1 442 ASN n 
1 443 LYS n 
1 444 TYR n 
1 445 MET n 
1 446 SER n 
1 447 HIS n 
1 448 ALA n 
1 449 SER n 
1 450 ILE n 
1 451 GLY n 
1 452 TRP n 
1 453 ARG n 
1 454 TYR n 
1 455 MET n 
1 456 ARG n 
1 457 ASP n 
1 458 ARG n 
1 459 LEU n 
1 460 ARG n 
1 461 GLU n 
1 462 SER n 
1 463 ALA n 
1 464 GLY n 
1 465 ASN n 
1 466 LYS n 
1 467 LYS n 
1 468 LEU n 
1 469 PRO n 
1 470 ILE n 
1 471 GLU n 
1 472 ARG n 
1 473 GLN n 
1 474 SER n 
1 475 GLY n 
1 476 ILE n 
1 477 TYR n 
1 478 THR n 
1 479 ALA n 
1 480 TYR n 
1 481 PHE n 
1 482 ARG n 
1 483 ARG n 
1 484 TRP n 
1 485 TRP n 
1 486 GLY n 
1 487 PHE n 
1 488 LYS n 
1 489 LYS n 
1 490 GLU n 
1 491 ARG n 
1 492 GLY n 
1 493 ASN n 
1 494 THR n 
1 495 LEU n 
1 496 HIS n 
1 497 HIS n 
1 498 ALA n 
1 499 LEU n 
1 500 ASP n 
1 501 ALA n 
1 502 VAL n 
1 503 ILE n 
1 504 LEU n 
1 505 ALA n 
1 506 SER n 
1 507 ARG n 
1 508 LYS n 
1 509 GLY n 
1 510 TYR n 
1 511 SER n 
1 512 ASP n 
1 513 ASP n 
1 514 GLY n 
1 515 LEU n 
1 516 VAL n 
1 517 ASP n 
1 518 MET n 
1 519 THR n 
1 520 LEU n 
1 521 LYS n 
1 522 PRO n 
1 523 LYS n 
1 524 TYR n 
1 525 ASN n 
1 526 LYS n 
1 527 GLY n 
1 528 GLY n 
1 529 GLU n 
1 530 PHE n 
1 531 ASP n 
1 532 PRO n 
1 533 GLU n 
1 534 LYS n 
1 535 HIS n 
1 536 LEU n 
1 537 PRO n 
1 538 GLU n 
1 539 PRO n 
1 540 ILE n 
1 541 GLU n 
1 542 PHE n 
1 543 LYS n 
1 544 MET n 
1 545 ASP n 
1 546 LYS n 
1 547 GLY n 
1 548 SER n 
1 549 ARG n 
1 550 GLY n 
1 551 SER n 
1 552 ALA n 
1 553 LEU n 
1 554 HIS n 
1 555 ASP n 
1 556 ARG n 
1 557 ASN n 
1 558 PRO n 
1 559 LEU n 
1 560 SER n 
1 561 TYR n 
1 562 LYS n 
1 563 LYS n 
1 564 GLY n 
1 565 ILE n 
1 566 ILE n 
1 567 THR n 
1 568 ARG n 
1 569 ARG n 
1 570 PHE n 
1 571 MET n 
1 572 VAL n 
1 573 THR n 
1 574 GLU n 
1 575 ILE n 
1 576 GLU n 
1 577 CYS n 
1 578 GLY n 
1 579 LYS n 
1 580 GLU n 
1 581 ASP n 
1 582 ASP n 
1 583 VAL n 
1 584 ILE n 
1 585 SER n 
1 586 GLU n 
1 587 THR n 
1 588 TYR n 
1 589 ARG n 
1 590 GLU n 
1 591 LYS n 
1 592 LEU n 
1 593 LYS n 
1 594 GLU n 
1 595 ALA n 
1 596 PHE n 
1 597 LYS n 
1 598 ARG n 
1 599 PHE n 
1 600 ASP n 
1 601 THR n 
1 602 LYS n 
1 603 LYS n 
1 604 GLY n 
1 605 LYS n 
1 606 CYS n 
1 607 LEU n 
1 608 THR n 
1 609 ASP n 
1 610 LYS n 
1 611 GLU n 
1 612 ALA n 
1 613 LYS n 
1 614 GLU n 
1 615 ALA n 
1 616 GLY n 
1 617 PHE n 
1 618 CYS n 
1 619 ILE n 
1 620 LYS n 
1 621 LYS n 
1 622 ASN n 
1 623 GLU n 
1 624 LEU n 
1 625 VAL n 
1 626 MET n 
1 627 SER n 
1 628 LEU n 
1 629 LYS n 
1 630 CYS n 
1 631 SER n 
1 632 ILE n 
1 633 LYS n 
1 634 GLY n 
1 635 THR n 
1 636 GLY n 
1 637 PRO n 
1 638 GLY n 
1 639 GLN n 
1 640 MET n 
1 641 ILE n 
1 642 ARG n 
1 643 ILE n 
1 644 ASN n 
1 645 ASN n 
1 646 ASN n 
1 647 VAL n 
1 648 PHE n 
1 649 LYS n 
1 650 THR n 
1 651 ASN n 
1 652 VAL n 
1 653 HIS n 
1 654 ASN n 
1 655 VAL n 
1 656 GLY n 
1 657 VAL n 
1 658 ASP n 
1 659 VAL n 
1 660 TYR n 
1 661 LEU n 
1 662 ASP n 
1 663 GLU n 
1 664 LYS n 
1 665 GLY n 
1 666 LYS n 
1 667 LYS n 
1 668 LYS n 
1 669 ALA n 
1 670 TYR n 
1 671 GLU n 
1 672 ARG n 
1 673 LYS n 
1 674 ASN n 
1 675 PRO n 
1 676 ARG n 
1 677 LEU n 
1 678 SER n 
1 679 LYS n 
1 680 HIS n 
1 681 PHE n 
1 682 ILE n 
1 683 GLU n 
1 684 PRO n 
1 685 PRO n 
1 686 PRO n 
1 687 GLN n 
1 688 PRO n 
1 689 ASN n 
1 690 GLY n 
1 691 ARG n 
1 692 VAL n 
1 693 SER n 
1 694 PHE n 
1 695 THR n 
1 696 LEU n 
1 697 LYS n 
1 698 ARG n 
1 699 ARG n 
1 700 ASP n 
1 701 MET n 
1 702 VAL n 
1 703 THR n 
1 704 VAL n 
1 705 GLU n 
1 706 GLY n 
1 707 GLU n 
1 708 ASP n 
1 709 ALA n 
1 710 ILE n 
1 711 TYR n 
1 712 ARG n 
1 713 ILE n 
1 714 LYS n 
1 715 LYS n 
1 716 LEU n 
1 717 GLY n 
1 718 THR n 
1 719 SER n 
1 720 PRO n 
1 721 THR n 
1 722 ILE n 
1 723 GLU n 
1 724 ALA n 
1 725 VAL n 
1 726 VAL n 
1 727 GLY n 
1 728 SER n 
1 729 ASP n 
1 730 GLY n 
1 731 LYS n 
1 732 THR n 
1 733 ARG n 
1 734 THR n 
1 735 VAL n 
1 736 SER n 
1 737 ALA n 
1 738 THR n 
1 739 LYS n 
1 740 LEU n 
1 741 THR n 
1 742 LYS n 
1 743 ALA n 
1 744 ASN n 
1 745 SER n 
1 746 ALA n 
1 747 GLU n 
1 748 ILE n 
1 749 GLU n 
1 750 GLN n 
1 751 SER n 
1 752 GLU n 
1 753 LYS n 
1 754 ASP n 
1 755 ASN n 
1 756 LEU n 
1 757 LYS n 
1 758 ASP n 
1 759 ALA n 
1 760 VAL n 
1 761 LEU n 
1 762 ASP n 
1 763 LYS n 
1 764 ASN n 
1 765 ARG n 
1 766 ARG n 
1 767 GLU n 
1 768 GLU n 
1 769 VAL n 
1 770 LYS n 
1 771 SER n 
1 772 PHE n 
1 773 PHE n 
1 774 ARG n 
1 775 LYS n 
1 776 HIS n 
1 777 LYS n 
1 778 THR n 
1 779 ASP n 
1 780 GLU n 
1 781 HIS n 
1 782 ILE n 
1 783 ARG n 
1 784 LYS n 
1 785 GLN n 
1 786 VAL n 
1 787 TYR n 
1 788 ASP n 
1 789 ILE n 
1 790 ALA n 
1 791 ASP n 
1 792 ASN n 
1 793 LYS n 
1 794 LEU n 
1 795 SER n 
1 796 GLY n 
1 797 ARG n 
1 798 THR n 
1 799 VAL n 
1 800 PHE n 
1 801 CYS n 
1 802 LYS n 
1 803 GLU n 
1 804 HIS n 
1 805 ILE n 
1 806 LEU n 
1 807 SER n 
1 808 ARG n 
1 809 GLY n 
1 810 SER n 
1 811 ALA n 
1 812 LEU n 
1 813 HIS n 
1 814 ASP n 
1 815 ARG n 
1 816 ASN n 
1 817 PRO n 
1 818 LEU n 
1 819 SER n 
1 820 TYR n 
1 821 LYS n 
1 822 LYS n 
1 823 GLY n 
1 824 ILE n 
1 825 ILE n 
1 826 THR n 
1 827 ARG n 
1 828 ARG n 
1 829 PHE n 
1 830 MET n 
1 831 VAL n 
1 832 THR n 
1 833 GLU n 
1 834 ILE n 
1 835 GLU n 
1 836 CYS n 
1 837 GLY n 
1 838 LYS n 
1 839 GLU n 
1 840 ASP n 
1 841 ASP n 
1 842 VAL n 
1 843 ILE n 
1 844 SER n 
1 845 GLU n 
1 846 THR n 
1 847 TYR n 
1 848 ARG n 
1 849 GLU n 
1 850 LYS n 
1 851 LEU n 
1 852 LYS n 
1 853 GLU n 
1 854 ALA n 
1 855 PHE n 
1 856 LYS n 
1 857 ARG n 
1 858 PHE n 
1 859 ASP n 
1 860 THR n 
1 861 LYS n 
1 862 LYS n 
1 863 GLY n 
1 864 LYS n 
1 865 CYS n 
1 866 LEU n 
1 867 THR n 
1 868 ASP n 
1 869 LYS n 
1 870 GLU n 
1 871 ALA n 
1 872 LYS n 
1 873 GLU n 
1 874 ALA n 
1 875 GLY n 
1 876 PHE n 
1 877 CYS n 
1 878 ILE n 
1 879 LYS n 
1 880 LYS n 
1 881 ASN n 
1 882 GLU n 
1 883 LEU n 
1 884 VAL n 
1 885 MET n 
1 886 SER n 
1 887 LEU n 
1 888 LYS n 
1 889 CYS n 
1 890 SER n 
1 891 ILE n 
1 892 LYS n 
1 893 GLY n 
1 894 THR n 
1 895 GLY n 
1 896 PRO n 
1 897 GLY n 
1 898 GLN n 
1 899 MET n 
1 900 ILE n 
1 901 ARG n 
1 902 ILE n 
1 903 ASN n 
1 904 ASN n 
1 905 ASN n 
1 906 VAL n 
1 907 PHE n 
1 908 LYS n 
1 909 THR n 
1 910 ASN n 
1 911 VAL n 
1 912 HIS n 
1 913 ASN n 
1 914 VAL n 
1 915 UNK n 
1 916 UNK n 
1 917 UNK n 
1 918 UNK n 
1 919 UNK n 
1 920 UNK n 
1 921 UNK n 
1 922 UNK n 
1 923 UNK n 
1 924 UNK n 
1 925 UNK n 
1 926 UNK n 
1 927 UNK n 
1 928 UNK n 
1 929 UNK n 
1 930 UNK n 
1 931 ARG n 
1 932 LYS n 
1 933 ASN n 
1 934 PRO n 
1 935 ARG n 
1 936 LEU n 
1 937 SER n 
1 938 LYS n 
1 939 HIS n 
1 940 PHE n 
1 941 ILE n 
1 942 GLU n 
2 1   G   n 
2 2   A   n 
2 3   C   n 
2 4   G   n 
2 5   C   n 
2 6   A   n 
2 7   U   n 
2 8   A   n 
2 9   A   n 
2 10  A   n 
2 11  G   n 
2 12  A   n 
2 13  U   n 
2 14  G   n 
2 15  A   n 
2 16  G   n 
2 17  A   n 
2 18  C   n 
2 19  G   n 
2 20  C   n 
2 21  G   n 
2 22  U   n 
2 23  U   n 
2 24  A   n 
2 25  C   n 
2 26  A   n 
2 27  G   n 
2 28  U   n 
2 29  U   n 
2 30  A   n 
2 31  A   n 
2 32  G   n 
2 33  G   n 
2 34  C   n 
2 35  U   n 
2 36  C   n 
2 37  U   n 
2 38  G   n 
2 39  A   n 
2 40  A   n 
2 41  A   n 
2 42  A   n 
2 43  G   n 
2 44  A   n 
2 45  G   n 
2 46  C   n 
2 47  C   n 
2 48  U   n 
2 49  U   n 
2 50  A   n 
2 51  A   n 
2 52  U   n 
2 53  U   n 
2 54  G   n 
2 55  U   n 
2 56  A   n 
2 57  A   n 
2 58  A   n 
2 59  A   n 
2 60  C   n 
2 61  G   n 
2 62  C   n 
2 63  C   n 
2 64  U   n 
2 65  A   n 
2 66  U   n 
2 67  A   n 
2 68  C   n 
2 69  A   n 
2 70  G   n 
2 71  U   n 
2 72  G   n 
2 73  A   n 
2 74  A   n 
2 75  G   n 
2 76  G   n 
2 77  G   n 
2 78  A   n 
2 79  U   n 
2 80  A   n 
2 81  U   n 
2 82  A   n 
2 83  C   n 
2 84  G   n 
2 85  C   n 
2 86  U   n 
2 87  U   n 
2 88  G   n 
2 89  G   n 
2 90  G   n 
2 91  U   n 
2 92  U   n 
2 93  U   n 
2 94  G   n 
2 95  U   n 
2 96  C   n 
2 97  C   n 
2 98  A   n 
2 99  G   n 
2 100 C   n 
2 101 C   n 
2 102 U   n 
2 103 G   n 
2 104 A   n 
2 105 G   n 
2 106 C   n 
2 107 C   n 
2 108 U   n 
2 109 C   n 
2 110 U   n 
2 111 A   n 
2 112 U   n 
2 113 G   n 
2 114 C   n 
2 115 C   n 
2 116 A   n 
2 117 G   n 
2 118 A   n 
2 119 A   n 
2 120 A   n 
2 121 U   n 
2 122 G   n 
2 123 G   n 
2 124 C   n 
2 125 G   n 
2 126 C   n 
2 127 C   n 
2 128 U   n 
2 129 U   n 
2 130 C   n 
2 131 A   n 
2 132 U   n 
2 133 C   n 
2 134 G   n 
2 135 U   n 
2 136 G   n 
2 137 G   n 
2 138 G   n 
2 139 U   n 
2 140 U   n 
2 141 A   n 
2 142 G   n 
2 143 G   n 
2 144 A   n 
2 145 C   n 
2 146 A   n 
2 147 U   n 
2 148 U   n 
2 149 U   n 
2 150 A   n 
2 151 A   n 
2 152 U   n 
2 153 U   n 
2 154 U   n 
2 155 U   n 
2 156 U   n 
2 157 U   n 
2 158 U   n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 942 ? ? A2022_01700 ? ? ? ? ? ? Deltaproteobacteria 28221 ? ? ? ? ? ? ? ? 
'Escherichia coli BL21(DE3)' 469008 ? ? ? ? ? ? 'NICO DE3' ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 158 ? ? ?           ? ? ? ? ? ? Deltaproteobacteria 28221 ? ? ? ? ? ? ? ? 'Escherichia coli' 
562    ? ? ? ? ? ? ?          ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
A   'RNA linking'       y "ADENOSINE-5'-MONOPHOSPHATE" ? 'C10 H14 N5 O7 P' 347.221 
ALA 'L-peptide linking' y ALANINE                      ? 'C3 H7 N O2'      89.093  
ARG 'L-peptide linking' y ARGININE                     ? 'C6 H15 N4 O2 1'  175.209 
ASN 'L-peptide linking' y ASPARAGINE                   ? 'C4 H8 N2 O3'     132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'              ? 'C4 H7 N O4'      133.103 
C   'RNA linking'       y "CYTIDINE-5'-MONOPHOSPHATE"  ? 'C9 H14 N3 O8 P'  323.197 
CYS 'L-peptide linking' y CYSTEINE                     ? 'C3 H7 N O2 S'    121.158 
G   'RNA linking'       y "GUANOSINE-5'-MONOPHOSPHATE" ? 'C10 H14 N5 O8 P' 363.221 
GLN 'L-peptide linking' y GLUTAMINE                    ? 'C5 H10 N2 O3'    146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'              ? 'C5 H9 N O4'      147.129 
GLY 'peptide linking'   y GLYCINE                      ? 'C2 H5 N O2'      75.067  
HIS 'L-peptide linking' y HISTIDINE                    ? 'C6 H10 N3 O2 1'  156.162 
ILE 'L-peptide linking' y ISOLEUCINE                   ? 'C6 H13 N O2'     131.173 
LEU 'L-peptide linking' y LEUCINE                      ? 'C6 H13 N O2'     131.173 
LYS 'L-peptide linking' y LYSINE                       ? 'C6 H15 N2 O2 1'  147.195 
MET 'L-peptide linking' y METHIONINE                   ? 'C5 H11 N O2 S'   149.211 
PHE 'L-peptide linking' y PHENYLALANINE                ? 'C9 H11 N O2'     165.189 
PRO 'L-peptide linking' y PROLINE                      ? 'C5 H9 N O2'      115.130 
SER 'L-peptide linking' y SERINE                       ? 'C3 H7 N O3'      105.093 
THR 'L-peptide linking' y THREONINE                    ? 'C4 H9 N O3'      119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                   ? 'C11 H12 N2 O2'   204.225 
TYR 'L-peptide linking' y TYROSINE                     ? 'C9 H11 N O3'     181.189 
U   'RNA linking'       y "URIDINE-5'-MONOPHOSPHATE"   ? 'C9 H13 N2 O9 P'  324.181 
UNK 'L-peptide linking' . UNKNOWN                      ? 'C4 H9 N O2'      103.120 
VAL 'L-peptide linking' y VALINE                       ? 'C5 H11 N O2'     117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   GLU 2   2   ?   ?   ?   A . n 
A 1 3   ARG 3   3   ?   ?   ?   A . n 
A 1 4   GLU 4   4   ?   ?   ?   A . n 
A 1 5   LEU 5   5   ?   ?   ?   A . n 
A 1 6   VAL 6   6   ?   ?   ?   A . n 
A 1 7   LEU 7   7   ?   ?   ?   A . n 
A 1 8   GLY 8   8   ?   ?   ?   A . n 
A 1 9   ILE 9   9   ?   ?   ?   A . n 
A 1 10  ASP 10  10  ?   ?   ?   A . n 
A 1 11  TYR 11  11  ?   ?   ?   A . n 
A 1 12  GLY 12  12  ?   ?   ?   A . n 
A 1 13  GLY 13  13  ?   ?   ?   A . n 
A 1 14  LYS 14  14  ?   ?   ?   A . n 
A 1 15  TYR 15  15  ?   ?   ?   A . n 
A 1 16  THR 16  16  ?   ?   ?   A . n 
A 1 17  GLY 17  17  ?   ?   ?   A . n 
A 1 18  LEU 18  18  ?   ?   ?   A . n 
A 1 19  ALA 19  19  ?   ?   ?   A . n 
A 1 20  VAL 20  20  ?   ?   ?   A . n 
A 1 21  VAL 21  21  ?   ?   ?   A . n 
A 1 22  ASP 22  22  ?   ?   ?   A . n 
A 1 23  ARG 23  23  ?   ?   ?   A . n 
A 1 24  ARG 24  24  ?   ?   ?   A . n 
A 1 25  HIS 25  25  ?   ?   ?   A . n 
A 1 26  ASN 26  26  ?   ?   ?   A . n 
A 1 27  GLN 27  27  ?   ?   ?   A . n 
A 1 28  VAL 28  28  ?   ?   ?   A . n 
A 1 29  LEU 29  29  ?   ?   ?   A . n 
A 1 30  TYR 30  30  ?   ?   ?   A . n 
A 1 31  ALA 31  31  ?   ?   ?   A . n 
A 1 32  ASN 32  32  ?   ?   ?   A . n 
A 1 33  ARG 33  33  ?   ?   ?   A . n 
A 1 34  LEU 34  34  ?   ?   ?   A . n 
A 1 35  LYS 35  35  ?   ?   ?   A . n 
A 1 36  MET 36  36  ?   ?   ?   A . n 
A 1 37  ARG 37  37  ?   ?   ?   A . n 
A 1 38  ASP 38  38  ?   ?   ?   A . n 
A 1 39  ASP 39  39  ?   ?   ?   A . n 
A 1 40  VAL 40  40  ?   ?   ?   A . n 
A 1 41  ALA 41  41  ?   ?   ?   A . n 
A 1 42  GLY 42  42  ?   ?   ?   A . n 
A 1 43  ILE 43  43  43  ILE ILE A . n 
A 1 44  LEU 44  44  44  LEU LEU A . n 
A 1 45  LYS 45  45  45  LYS LYS A . n 
A 1 46  ASP 46  46  46  ASP ASP A . n 
A 1 47  ARG 47  47  47  ARG ARG A . n 
A 1 48  ARG 48  48  48  ARG ARG A . n 
A 1 49  LYS 49  49  49  LYS LYS A . n 
A 1 50  GLN 50  50  50  GLN GLN A . n 
A 1 51  ARG 51  51  51  ARG ARG A . n 
A 1 52  GLY 52  52  52  GLY GLY A . n 
A 1 53  ILE 53  53  53  ILE ILE A . n 
A 1 54  ARG 54  54  54  ARG ARG A . n 
A 1 55  ARG 55  55  55  ARG ARG A . n 
A 1 56  THR 56  56  56  THR THR A . n 
A 1 57  ALA 57  57  57  ALA ALA A . n 
A 1 58  GLN 58  58  58  GLN GLN A . n 
A 1 59  THR 59  59  59  THR THR A . n 
A 1 60  LYS 60  60  60  LYS LYS A . n 
A 1 61  LYS 61  61  61  LYS LYS A . n 
A 1 62  LYS 62  62  62  LYS LYS A . n 
A 1 63  ARG 63  63  63  ARG ARG A . n 
A 1 64  LEU 64  64  64  LEU LEU A . n 
A 1 65  ARG 65  65  65  ARG ARG A . n 
A 1 66  GLU 66  66  66  GLU GLU A . n 
A 1 67  LEU 67  67  67  LEU LEU A . n 
A 1 68  LYS 68  68  68  LYS LYS A . n 
A 1 69  ASN 69  69  69  ASN ASN A . n 
A 1 70  TYR 70  70  70  TYR TYR A . n 
A 1 71  LEU 71  71  71  LEU LEU A . n 
A 1 72  LYS 72  72  72  LYS LYS A . n 
A 1 73  SER 73  73  73  SER SER A . n 
A 1 74  ILE 74  74  74  ILE ILE A . n 
A 1 75  GLY 75  75  75  GLY GLY A . n 
A 1 76  TYR 76  76  76  TYR TYR A . n 
A 1 77  ASN 77  77  77  ASN ASN A . n 
A 1 78  GLU 78  78  78  GLU GLU A . n 
A 1 79  SER 79  79  79  SER SER A . n 
A 1 80  THR 80  80  80  THR THR A . n 
A 1 81  ALA 81  81  81  ALA ALA A . n 
A 1 82  THR 82  82  82  THR THR A . n 
A 1 83  PHE 83  83  83  PHE PHE A . n 
A 1 84  GLU 84  84  84  GLU GLU A . n 
A 1 85  THR 85  85  85  THR THR A . n 
A 1 86  VAL 86  86  86  VAL VAL A . n 
A 1 87  TYR 87  87  87  TYR TYR A . n 
A 1 88  SER 88  88  88  SER SER A . n 
A 1 89  LEU 89  89  89  LEU LEU A . n 
A 1 90  ALA 90  90  90  ALA ALA A . n 
A 1 91  HIS 91  91  91  HIS HIS A . n 
A 1 92  LYS 92  92  92  LYS LYS A . n 
A 1 93  ARG 93  93  93  ARG ARG A . n 
A 1 94  GLY 94  94  94  GLY GLY A . n 
A 1 95  TYR 95  95  95  TYR TYR A . n 
A 1 96  ASP 96  96  96  ASP ASP A . n 
A 1 97  TYR 97  97  97  TYR TYR A . n 
A 1 98  ALA 98  98  98  ALA ALA A . n 
A 1 99  ASP 99  99  99  ASP ASP A . n 
A 1 100 MET 100 100 100 MET MET A . n 
A 1 101 PRO 101 101 101 PRO PRO A . n 
A 1 102 GLU 102 102 102 GLU GLU A . n 
A 1 103 GLU 103 103 103 GLU GLU A . n 
A 1 104 LYS 104 104 104 LYS LYS A . n 
A 1 105 THR 105 105 105 THR THR A . n 
A 1 106 SER 106 106 106 SER SER A . n 
A 1 107 GLU 107 107 107 GLU GLU A . n 
A 1 108 GLU 108 108 108 GLU GLU A . n 
A 1 109 ILE 109 109 109 ILE ILE A . n 
A 1 110 GLU 110 110 110 GLU GLU A . n 
A 1 111 ALA 111 111 111 ALA ALA A . n 
A 1 112 MET 112 112 112 MET MET A . n 
A 1 113 ASP 113 113 113 ASP ASP A . n 
A 1 114 VAL 114 114 114 VAL VAL A . n 
A 1 115 GLU 115 115 115 GLU GLU A . n 
A 1 116 GLU 116 116 116 GLU GLU A . n 
A 1 117 ARG 117 117 117 ARG ARG A . n 
A 1 118 LYS 118 118 118 LYS LYS A . n 
A 1 119 GLN 119 119 119 GLN GLN A . n 
A 1 120 TRP 120 120 120 TRP TRP A . n 
A 1 121 GLU 121 121 121 GLU GLU A . n 
A 1 122 LYS 122 122 122 LYS LYS A . n 
A 1 123 GLU 123 123 123 GLU GLU A . n 
A 1 124 LYS 124 124 124 LYS LYS A . n 
A 1 125 GLN 125 125 125 GLN GLN A . n 
A 1 126 GLU 126 126 126 GLU GLU A . n 
A 1 127 TRP 127 127 127 TRP TRP A . n 
A 1 128 GLU 128 128 128 GLU GLU A . n 
A 1 129 GLU 129 129 129 GLU GLU A . n 
A 1 130 THR 130 130 130 THR THR A . n 
A 1 131 LYS 131 131 131 LYS LYS A . n 
A 1 132 ARG 132 132 132 ARG ARG A . n 
A 1 133 ASN 133 133 133 ASN ASN A . n 
A 1 134 SER 134 134 134 SER SER A . n 
A 1 135 ARG 135 135 135 ARG ARG A . n 
A 1 136 HIS 136 136 136 HIS HIS A . n 
A 1 137 ARG 137 137 137 ARG ARG A . n 
A 1 138 LYS 138 138 138 LYS LYS A . n 
A 1 139 GLU 139 139 139 GLU GLU A . n 
A 1 140 VAL 140 140 140 VAL VAL A . n 
A 1 141 VAL 141 141 141 VAL VAL A . n 
A 1 142 LYS 142 142 142 LYS LYS A . n 
A 1 143 ASP 143 143 143 ASP ASP A . n 
A 1 144 VAL 144 144 144 VAL VAL A . n 
A 1 145 HIS 145 145 145 HIS HIS A . n 
A 1 146 LYS 146 146 146 LYS LYS A . n 
A 1 147 ALA 147 147 147 ALA ALA A . n 
A 1 148 MET 148 148 148 MET MET A . n 
A 1 149 ILE 149 149 149 ILE ILE A . n 
A 1 150 GLU 150 150 150 GLU GLU A . n 
A 1 151 GLY 151 151 151 GLY GLY A . n 
A 1 152 ARG 152 152 152 ARG ARG A . n 
A 1 153 ALA 153 153 153 ALA ALA A . n 
A 1 154 THR 154 154 154 THR THR A . n 
A 1 155 GLU 155 155 155 GLU GLU A . n 
A 1 156 GLU 156 156 156 GLU GLU A . n 
A 1 157 GLN 157 157 157 GLN GLN A . n 
A 1 158 ILE 158 158 158 ILE ILE A . n 
A 1 159 LYS 159 159 159 LYS LYS A . n 
A 1 160 ARG 160 160 160 ARG ARG A . n 
A 1 161 VAL 161 161 161 VAL VAL A . n 
A 1 162 GLU 162 162 162 GLU GLU A . n 
A 1 163 ARG 163 163 163 ARG ARG A . n 
A 1 164 ILE 164 164 164 ILE ILE A . n 
A 1 165 PHE 165 165 165 PHE PHE A . n 
A 1 166 ASN 166 166 166 ASN ASN A . n 
A 1 167 LYS 167 167 167 LYS LYS A . n 
A 1 168 GLN 168 168 168 GLN GLN A . n 
A 1 169 TYR 169 169 169 TYR TYR A . n 
A 1 170 ARG 170 170 170 ARG ARG A . n 
A 1 171 PRO 171 171 171 PRO PRO A . n 
A 1 172 LYS 172 172 172 LYS LYS A . n 
A 1 173 ARG 173 173 173 ARG ARG A . n 
A 1 174 PHE 174 174 174 PHE PHE A . n 
A 1 175 ASN 175 175 175 ASN ASN A . n 
A 1 176 ASN 176 176 176 ASN ASN A . n 
A 1 177 ARG 177 177 177 ARG ARG A . n 
A 1 178 ILE 178 178 178 ILE ILE A . n 
A 1 179 LEU 179 179 179 LEU LEU A . n 
A 1 180 THR 180 180 180 THR THR A . n 
A 1 181 LYS 181 181 181 LYS LYS A . n 
A 1 182 CYS 182 182 182 CYS CYS A . n 
A 1 183 LYS 183 183 183 LYS LYS A . n 
A 1 184 VAL 184 184 184 VAL VAL A . n 
A 1 185 GLU 185 185 185 GLU GLU A . n 
A 1 186 ASP 186 186 186 ASP ASP A . n 
A 1 187 CYS 187 187 ?   ?   ?   A . n 
A 1 188 GLY 188 188 ?   ?   ?   A . n 
A 1 189 VAL 189 189 ?   ?   ?   A . n 
A 1 190 ASN 190 190 ?   ?   ?   A . n 
A 1 191 THR 191 191 ?   ?   ?   A . n 
A 1 192 PRO 192 192 ?   ?   ?   A . n 
A 1 193 LEU 193 193 ?   ?   ?   A . n 
A 1 194 ARG 194 194 ?   ?   ?   A . n 
A 1 195 LYS 195 195 195 LYS LYS A . n 
A 1 196 ASN 196 196 196 ASN ASN A . n 
A 1 197 VAL 197 197 197 VAL VAL A . n 
A 1 198 ARG 198 198 198 ARG ARG A . n 
A 1 199 ASP 199 199 199 ASP ASP A . n 
A 1 200 LEU 200 200 200 LEU LEU A . n 
A 1 201 LEU 201 201 201 LEU LEU A . n 
A 1 202 ILE 202 202 202 ILE ILE A . n 
A 1 203 GLU 203 203 203 GLU GLU A . n 
A 1 204 ASN 204 204 204 ASN ASN A . n 
A 1 205 ILE 205 205 205 ILE ILE A . n 
A 1 206 VAL 206 206 206 VAL VAL A . n 
A 1 207 ARG 207 207 207 ARG ARG A . n 
A 1 208 PHE 208 208 208 PHE PHE A . n 
A 1 209 PHE 209 209 209 PHE PHE A . n 
A 1 210 PRO 210 210 210 PRO PRO A . n 
A 1 211 ILE 211 211 211 ILE ILE A . n 
A 1 212 GLU 212 212 212 GLU GLU A . n 
A 1 213 GLN 213 213 213 GLN GLN A . n 
A 1 214 SER 214 214 214 SER SER A . n 
A 1 215 GLU 215 215 215 GLU GLU A . n 
A 1 216 LYS 216 216 216 LYS LYS A . n 
A 1 217 ASP 217 217 217 ASP ASP A . n 
A 1 218 ASN 218 218 218 ASN ASN A . n 
A 1 219 LEU 219 219 219 LEU LEU A . n 
A 1 220 LYS 220 220 220 LYS LYS A . n 
A 1 221 ASP 221 221 221 ASP ASP A . n 
A 1 222 ALA 222 222 222 ALA ALA A . n 
A 1 223 VAL 223 223 223 VAL VAL A . n 
A 1 224 LEU 224 224 224 LEU LEU A . n 
A 1 225 ASP 225 225 225 ASP ASP A . n 
A 1 226 LYS 226 226 226 LYS LYS A . n 
A 1 227 ASN 227 227 227 ASN ASN A . n 
A 1 228 ARG 228 228 228 ARG ARG A . n 
A 1 229 ARG 229 229 229 ARG ARG A . n 
A 1 230 GLU 230 230 230 GLU GLU A . n 
A 1 231 GLU 231 231 231 GLU GLU A . n 
A 1 232 VAL 232 232 232 VAL VAL A . n 
A 1 233 LYS 233 233 233 LYS LYS A . n 
A 1 234 SER 234 234 234 SER SER A . n 
A 1 235 PHE 235 235 235 PHE PHE A . n 
A 1 236 PHE 236 236 236 PHE PHE A . n 
A 1 237 ARG 237 237 237 ARG ARG A . n 
A 1 238 LYS 238 238 238 LYS LYS A . n 
A 1 239 HIS 239 239 239 HIS HIS A . n 
A 1 240 LYS 240 240 240 LYS LYS A . n 
A 1 241 THR 241 241 241 THR THR A . n 
A 1 242 ASP 242 242 242 ASP ASP A . n 
A 1 243 GLU 243 243 243 GLU GLU A . n 
A 1 244 HIS 244 244 244 HIS HIS A . n 
A 1 245 ILE 245 245 245 ILE ILE A . n 
A 1 246 ARG 246 246 246 ARG ARG A . n 
A 1 247 LYS 247 247 247 LYS LYS A . n 
A 1 248 GLN 248 248 248 GLN GLN A . n 
A 1 249 VAL 249 249 249 VAL VAL A . n 
A 1 250 TYR 250 250 250 TYR TYR A . n 
A 1 251 ASP 251 251 251 ASP ASP A . n 
A 1 252 ILE 252 252 252 ILE ILE A . n 
A 1 253 ALA 253 253 253 ALA ALA A . n 
A 1 254 ASP 254 254 254 ASP ASP A . n 
A 1 255 ASN 255 255 255 ASN ASN A . n 
A 1 256 LYS 256 256 256 LYS LYS A . n 
A 1 257 LEU 257 257 257 LEU LEU A . n 
A 1 258 SER 258 258 258 SER SER A . n 
A 1 259 GLY 259 259 259 GLY GLY A . n 
A 1 260 ARG 260 260 260 ARG ARG A . n 
A 1 261 THR 261 261 261 THR THR A . n 
A 1 262 VAL 262 262 262 VAL VAL A . n 
A 1 263 PHE 263 263 263 PHE PHE A . n 
A 1 264 CYS 264 264 264 CYS CYS A . n 
A 1 265 LYS 265 265 265 LYS LYS A . n 
A 1 266 GLU 266 266 266 GLU GLU A . n 
A 1 267 HIS 267 267 267 HIS HIS A . n 
A 1 268 ILE 268 268 268 ILE ILE A . n 
A 1 269 LEU 269 269 269 LEU LEU A . n 
A 1 270 GLU 270 269 ?   ?   ?   A A n 
A 1 271 HIS 271 269 ?   ?   ?   A B n 
A 1 272 THR 272 269 ?   ?   ?   A C n 
A 1 273 GLU 273 269 ?   ?   ?   A D n 
A 1 274 HIS 274 269 ?   ?   ?   A E n 
A 1 275 SER 275 269 ?   ?   ?   A F n 
A 1 276 LYS 276 269 ?   ?   ?   A G n 
A 1 277 GLU 277 269 ?   ?   ?   A H n 
A 1 278 GLU 278 269 ?   ?   ?   A I n 
A 1 279 ARG 279 269 ?   ?   ?   A J n 
A 1 280 LYS 280 269 ?   ?   ?   A K n 
A 1 281 VAL 281 269 ?   ?   ?   A L n 
A 1 282 PHE 282 269 ?   ?   ?   A M n 
A 1 283 ARG 283 269 ?   ?   ?   A N n 
A 1 284 LEU 284 269 ?   ?   ?   A O n 
A 1 285 ALA 285 269 ?   ?   ?   A P n 
A 1 286 PRO 286 269 ?   ?   ?   A Q n 
A 1 287 SER 287 269 ?   ?   ?   A R n 
A 1 288 LEU 288 269 ?   ?   ?   A S n 
A 1 289 LYS 289 269 ?   ?   ?   A T n 
A 1 290 THR 290 269 ?   ?   ?   A U n 
A 1 291 LYS 291 269 ?   ?   ?   A V n 
A 1 292 ILE 292 269 ?   ?   ?   A W n 
A 1 293 GLU 293 269 ?   ?   ?   A X n 
A 1 294 ASN 294 269 ?   ?   ?   A Y n 
A 1 295 VAL 295 269 ?   ?   ?   A Z n 
A 1 296 LEU 296 270 ?   ?   ?   A A n 
A 1 297 ALA 297 270 ?   ?   ?   A B n 
A 1 298 VAL 298 270 ?   ?   ?   A C n 
A 1 299 ILE 299 270 ?   ?   ?   A D n 
A 1 300 LYS 300 270 ?   ?   ?   A E n 
A 1 301 ASP 301 270 ?   ?   ?   A F n 
A 1 302 GLU 302 270 ?   ?   ?   A G n 
A 1 303 ILE 303 270 ?   ?   ?   A H n 
A 1 304 LEU 304 270 ?   ?   ?   A I n 
A 1 305 PRO 305 270 ?   ?   ?   A J n 
A 1 306 LYS 306 270 ?   ?   ?   A K n 
A 1 307 PHE 307 270 ?   ?   ?   A L n 
A 1 308 THR 308 270 ?   ?   ?   A M n 
A 1 309 VAL 309 270 ?   ?   ?   A N n 
A 1 310 ASN 310 270 ?   ?   ?   A O n 
A 1 311 LYS 311 270 ?   ?   ?   A P n 
A 1 312 VAL 312 270 ?   ?   ?   A Q n 
A 1 313 VAL 313 270 ?   ?   ?   A R n 
A 1 314 MET 314 270 ?   ?   ?   A S n 
A 1 315 GLU 315 270 ?   ?   ?   A T n 
A 1 316 SER 316 270 ?   ?   ?   A U n 
A 1 317 ASN 317 270 ?   ?   ?   A V n 
A 1 318 ASN 318 270 ?   ?   ?   A W n 
A 1 319 PHE 319 270 ?   ?   ?   A X n 
A 1 320 ASP 320 270 ?   ?   ?   A Y n 
A 1 321 ILE 321 270 ?   ?   ?   A Z n 
A 1 322 ALA 322 271 ?   ?   ?   A A n 
A 1 323 ALA 323 271 ?   ?   ?   A B n 
A 1 324 LYS 324 271 ?   ?   ?   A C n 
A 1 325 THR 325 271 ?   ?   ?   A D n 
A 1 326 GLN 326 271 ?   ?   ?   A E n 
A 1 327 GLY 327 271 ?   ?   ?   A F n 
A 1 328 LYS 328 271 ?   ?   ?   A G n 
A 1 329 LYS 329 271 ?   ?   ?   A H n 
A 1 330 ARG 330 271 ?   ?   ?   A I n 
A 1 331 LEU 331 271 ?   ?   ?   A J n 
A 1 332 ALA 332 271 ?   ?   ?   A K n 
A 1 333 LYS 333 271 ?   ?   ?   A L n 
A 1 334 GLU 334 271 ?   ?   ?   A M n 
A 1 335 GLU 335 271 ?   ?   ?   A N n 
A 1 336 TYR 336 271 ?   ?   ?   A O n 
A 1 337 GLY 337 271 ?   ?   ?   A P n 
A 1 338 LYS 338 271 ?   ?   ?   A Q n 
A 1 339 GLY 339 271 ?   ?   ?   A R n 
A 1 340 PRO 340 271 ?   ?   ?   A S n 
A 1 341 ARG 341 271 ?   ?   ?   A T n 
A 1 342 GLU 342 271 ?   ?   ?   A U n 
A 1 343 GLY 343 271 ?   ?   ?   A V n 
A 1 344 LYS 344 271 ?   ?   ?   A W n 
A 1 345 GLU 345 271 ?   ?   ?   A X n 
A 1 346 THR 346 271 ?   ?   ?   A Y n 
A 1 347 ARG 347 271 ?   ?   ?   A Z n 
A 1 348 LYS 348 272 ?   ?   ?   A A n 
A 1 349 GLU 349 272 ?   ?   ?   A B n 
A 1 350 ALA 350 272 ?   ?   ?   A C n 
A 1 351 LEU 351 272 ?   ?   ?   A D n 
A 1 352 LEU 352 272 ?   ?   ?   A E n 
A 1 353 ARG 353 272 ?   ?   ?   A F n 
A 1 354 GLU 354 272 ?   ?   ?   A G n 
A 1 355 THR 355 272 ?   ?   ?   A H n 
A 1 356 ASP 356 272 ?   ?   ?   A I n 
A 1 357 GLY 357 272 ?   ?   ?   A J n 
A 1 358 ARG 358 272 ?   ?   ?   A K n 
A 1 359 CYS 359 272 ?   ?   ?   A L n 
A 1 360 ILE 360 272 ?   ?   ?   A M n 
A 1 361 TYR 361 272 ?   ?   ?   A N n 
A 1 362 CYS 362 272 ?   ?   ?   A O n 
A 1 363 GLY 363 272 ?   ?   ?   A P n 
A 1 364 LYS 364 272 ?   ?   ?   A Q n 
A 1 365 SER 365 272 ?   ?   ?   A R n 
A 1 366 ILE 366 272 ?   ?   ?   A S n 
A 1 367 ASP 367 272 ?   ?   ?   A T n 
A 1 368 ILE 368 272 ?   ?   ?   A U n 
A 1 369 SER 369 272 ?   ?   ?   A V n 
A 1 370 ASN 370 272 ?   ?   ?   A W n 
A 1 371 ALA 371 272 ?   ?   ?   A X n 
A 1 372 HIS 372 272 ?   ?   ?   A Y n 
A 1 373 ASP 373 272 ?   ?   ?   A Z n 
A 1 374 ASP 374 273 ?   ?   ?   A A n 
A 1 375 HIS 375 273 ?   ?   ?   A B n 
A 1 376 ILE 376 273 ?   ?   ?   A C n 
A 1 377 PHE 377 273 ?   ?   ?   A D n 
A 1 378 PRO 378 273 ?   ?   ?   A E n 
A 1 379 ARG 379 273 ?   ?   ?   A F n 
A 1 380 LYS 380 273 ?   ?   ?   A G n 
A 1 381 ALA 381 273 ?   ?   ?   A H n 
A 1 382 GLY 382 273 ?   ?   ?   A I n 
A 1 383 GLY 383 273 ?   ?   ?   A J n 
A 1 384 LEU 384 273 ?   ?   ?   A K n 
A 1 385 ASN 385 273 ?   ?   ?   A L n 
A 1 386 ILE 386 273 ?   ?   ?   A M n 
A 1 387 PHE 387 273 ?   ?   ?   A N n 
A 1 388 ALA 388 273 ?   ?   ?   A O n 
A 1 389 ASN 389 273 ?   ?   ?   A P n 
A 1 390 LEU 390 273 ?   ?   ?   A Q n 
A 1 391 VAL 391 273 ?   ?   ?   A R n 
A 1 392 ALA 392 273 ?   ?   ?   A S n 
A 1 393 CYS 393 273 ?   ?   ?   A T n 
A 1 394 CYS 394 273 ?   ?   ?   A U n 
A 1 395 ALA 395 273 ?   ?   ?   A V n 
A 1 396 VAL 396 273 ?   ?   ?   A W n 
A 1 397 CYS 397 273 ?   ?   ?   A X n 
A 1 398 ASN 398 273 ?   ?   ?   A Y n 
A 1 399 GLU 399 273 ?   ?   ?   A Z n 
A 1 400 ASN 400 274 ?   ?   ?   A A n 
A 1 401 LYS 401 274 ?   ?   ?   A B n 
A 1 402 LYS 402 274 ?   ?   ?   A C n 
A 1 403 GLY 403 274 ?   ?   ?   A D n 
A 1 404 ARG 404 274 ?   ?   ?   A E n 
A 1 405 THR 405 274 ?   ?   ?   A F n 
A 1 406 PRO 406 274 ?   ?   ?   A G n 
A 1 407 LEU 407 274 ?   ?   ?   A H n 
A 1 408 GLU 408 274 ?   ?   ?   A I n 
A 1 409 SER 409 274 ?   ?   ?   A J n 
A 1 410 GLY 410 274 ?   ?   ?   A K n 
A 1 411 ILE 411 274 ?   ?   ?   A L n 
A 1 412 SER 412 274 ?   ?   ?   A M n 
A 1 413 PRO 413 274 ?   ?   ?   A N n 
A 1 414 LYS 414 274 ?   ?   ?   A O n 
A 1 415 PRO 415 274 ?   ?   ?   A P n 
A 1 416 GLU 416 274 ?   ?   ?   A Q n 
A 1 417 ILE 417 274 ?   ?   ?   A R n 
A 1 418 ILE 418 274 ?   ?   ?   A S n 
A 1 419 ALA 419 274 ?   ?   ?   A T n 
A 1 420 PHE 420 274 ?   ?   ?   A U n 
A 1 421 MET 421 274 ?   ?   ?   A V n 
A 1 422 LYS 422 274 ?   ?   ?   A W n 
A 1 423 ASN 423 274 ?   ?   ?   A X n 
A 1 424 ASP 424 274 ?   ?   ?   A Y n 
A 1 425 LEU 425 274 ?   ?   ?   A Z n 
A 1 426 LYS 426 275 ?   ?   ?   A A n 
A 1 427 LYS 427 275 ?   ?   ?   A B n 
A 1 428 LYS 428 275 ?   ?   ?   A C n 
A 1 429 ILE 429 275 ?   ?   ?   A D n 
A 1 430 LEU 430 275 ?   ?   ?   A E n 
A 1 431 GLU 431 275 ?   ?   ?   A F n 
A 1 432 ASP 432 275 ?   ?   ?   A G n 
A 1 433 ALA 433 275 ?   ?   ?   A H n 
A 1 434 ARG 434 275 ?   ?   ?   A I n 
A 1 435 ASN 435 275 ?   ?   ?   A J n 
A 1 436 ILE 436 275 ?   ?   ?   A K n 
A 1 437 ASN 437 275 ?   ?   ?   A L n 
A 1 438 THR 438 275 ?   ?   ?   A M n 
A 1 439 VAL 439 275 ?   ?   ?   A N n 
A 1 440 ASP 440 275 ?   ?   ?   A O n 
A 1 441 PHE 441 275 ?   ?   ?   A P n 
A 1 442 ASN 442 275 ?   ?   ?   A Q n 
A 1 443 LYS 443 275 ?   ?   ?   A R n 
A 1 444 TYR 444 275 ?   ?   ?   A S n 
A 1 445 MET 445 275 ?   ?   ?   A T n 
A 1 446 SER 446 275 ?   ?   ?   A U n 
A 1 447 HIS 447 275 ?   ?   ?   A V n 
A 1 448 ALA 448 275 ?   ?   ?   A W n 
A 1 449 SER 449 275 ?   ?   ?   A X n 
A 1 450 ILE 450 275 ?   ?   ?   A Y n 
A 1 451 GLY 451 275 ?   ?   ?   A Z n 
A 1 452 TRP 452 276 ?   ?   ?   A A n 
A 1 453 ARG 453 276 ?   ?   ?   A B n 
A 1 454 TYR 454 276 ?   ?   ?   A C n 
A 1 455 MET 455 276 ?   ?   ?   A D n 
A 1 456 ARG 456 276 ?   ?   ?   A E n 
A 1 457 ASP 457 276 ?   ?   ?   A F n 
A 1 458 ARG 458 276 ?   ?   ?   A G n 
A 1 459 LEU 459 276 ?   ?   ?   A H n 
A 1 460 ARG 460 276 ?   ?   ?   A I n 
A 1 461 GLU 461 276 ?   ?   ?   A J n 
A 1 462 SER 462 276 ?   ?   ?   A K n 
A 1 463 ALA 463 276 ?   ?   ?   A L n 
A 1 464 GLY 464 276 ?   ?   ?   A M n 
A 1 465 ASN 465 276 ?   ?   ?   A N n 
A 1 466 LYS 466 276 ?   ?   ?   A O n 
A 1 467 LYS 467 276 ?   ?   ?   A P n 
A 1 468 LEU 468 276 ?   ?   ?   A Q n 
A 1 469 PRO 469 276 ?   ?   ?   A R n 
A 1 470 ILE 470 276 ?   ?   ?   A S n 
A 1 471 GLU 471 276 ?   ?   ?   A T n 
A 1 472 ARG 472 276 ?   ?   ?   A U n 
A 1 473 GLN 473 276 ?   ?   ?   A V n 
A 1 474 SER 474 276 ?   ?   ?   A W n 
A 1 475 GLY 475 276 ?   ?   ?   A X n 
A 1 476 ILE 476 276 ?   ?   ?   A Y n 
A 1 477 TYR 477 276 ?   ?   ?   A Z n 
A 1 478 THR 478 277 ?   ?   ?   A A n 
A 1 479 ALA 479 277 ?   ?   ?   A B n 
A 1 480 TYR 480 277 ?   ?   ?   A C n 
A 1 481 PHE 481 277 ?   ?   ?   A D n 
A 1 482 ARG 482 277 ?   ?   ?   A E n 
A 1 483 ARG 483 277 ?   ?   ?   A F n 
A 1 484 TRP 484 277 ?   ?   ?   A G n 
A 1 485 TRP 485 277 ?   ?   ?   A H n 
A 1 486 GLY 486 277 ?   ?   ?   A I n 
A 1 487 PHE 487 277 ?   ?   ?   A J n 
A 1 488 LYS 488 277 ?   ?   ?   A K n 
A 1 489 LYS 489 277 ?   ?   ?   A L n 
A 1 490 GLU 490 277 ?   ?   ?   A M n 
A 1 491 ARG 491 277 ?   ?   ?   A N n 
A 1 492 GLY 492 277 ?   ?   ?   A O n 
A 1 493 ASN 493 277 ?   ?   ?   A P n 
A 1 494 THR 494 277 ?   ?   ?   A Q n 
A 1 495 LEU 495 277 ?   ?   ?   A R n 
A 1 496 HIS 496 277 ?   ?   ?   A S n 
A 1 497 HIS 497 277 ?   ?   ?   A T n 
A 1 498 ALA 498 277 ?   ?   ?   A U n 
A 1 499 LEU 499 277 ?   ?   ?   A V n 
A 1 500 ASP 500 277 ?   ?   ?   A W n 
A 1 501 ALA 501 277 ?   ?   ?   A X n 
A 1 502 VAL 502 277 ?   ?   ?   A Y n 
A 1 503 ILE 503 277 ?   ?   ?   A Z n 
A 1 504 LEU 504 278 ?   ?   ?   A A n 
A 1 505 ALA 505 278 ?   ?   ?   A B n 
A 1 506 SER 506 278 ?   ?   ?   A C n 
A 1 507 ARG 507 278 ?   ?   ?   A D n 
A 1 508 LYS 508 278 ?   ?   ?   A E n 
A 1 509 GLY 509 278 ?   ?   ?   A F n 
A 1 510 TYR 510 278 ?   ?   ?   A G n 
A 1 511 SER 511 278 ?   ?   ?   A H n 
A 1 512 ASP 512 278 ?   ?   ?   A I n 
A 1 513 ASP 513 278 ?   ?   ?   A J n 
A 1 514 GLY 514 278 ?   ?   ?   A K n 
A 1 515 LEU 515 278 ?   ?   ?   A L n 
A 1 516 VAL 516 278 ?   ?   ?   A M n 
A 1 517 ASP 517 278 ?   ?   ?   A N n 
A 1 518 MET 518 278 ?   ?   ?   A O n 
A 1 519 THR 519 278 ?   ?   ?   A P n 
A 1 520 LEU 520 278 ?   ?   ?   A Q n 
A 1 521 LYS 521 278 ?   ?   ?   A R n 
A 1 522 PRO 522 278 ?   ?   ?   A S n 
A 1 523 LYS 523 278 ?   ?   ?   A T n 
A 1 524 TYR 524 278 ?   ?   ?   A U n 
A 1 525 ASN 525 278 ?   ?   ?   A V n 
A 1 526 LYS 526 278 ?   ?   ?   A W n 
A 1 527 GLY 527 278 ?   ?   ?   A X n 
A 1 528 GLY 528 278 ?   ?   ?   A Y n 
A 1 529 GLU 529 278 ?   ?   ?   A Z n 
A 1 530 PHE 530 279 ?   ?   ?   A A n 
A 1 531 ASP 531 279 ?   ?   ?   A B n 
A 1 532 PRO 532 279 ?   ?   ?   A C n 
A 1 533 GLU 533 279 ?   ?   ?   A D n 
A 1 534 LYS 534 279 ?   ?   ?   A E n 
A 1 535 HIS 535 279 ?   ?   ?   A F n 
A 1 536 LEU 536 279 ?   ?   ?   A G n 
A 1 537 PRO 537 279 ?   ?   ?   A H n 
A 1 538 GLU 538 279 ?   ?   ?   A I n 
A 1 539 PRO 539 279 ?   ?   ?   A J n 
A 1 540 ILE 540 279 ?   ?   ?   A K n 
A 1 541 GLU 541 279 ?   ?   ?   A L n 
A 1 542 PHE 542 279 ?   ?   ?   A M n 
A 1 543 LYS 543 279 ?   ?   ?   A N n 
A 1 544 MET 544 279 ?   ?   ?   A O n 
A 1 545 ASP 545 279 ?   ?   ?   A P n 
A 1 546 LYS 546 279 ?   ?   ?   A Q n 
A 1 547 GLY 547 279 ?   ?   ?   A R n 
A 1 548 SER 548 279 ?   ?   ?   A S n 
A 1 549 ARG 549 279 ?   ?   ?   A T n 
A 1 550 GLY 550 279 ?   ?   ?   A U n 
A 1 551 SER 551 279 ?   ?   ?   A V n 
A 1 552 ALA 552 279 ?   ?   ?   A W n 
A 1 553 LEU 553 279 ?   ?   ?   A X n 
A 1 554 HIS 554 279 ?   ?   ?   A Y n 
A 1 555 ASP 555 279 ?   ?   ?   A Z n 
A 1 556 ARG 556 280 ?   ?   ?   A A n 
A 1 557 ASN 557 280 ?   ?   ?   A B n 
A 1 558 PRO 558 280 ?   ?   ?   A C n 
A 1 559 LEU 559 280 ?   ?   ?   A D n 
A 1 560 SER 560 280 ?   ?   ?   A E n 
A 1 561 TYR 561 280 ?   ?   ?   A F n 
A 1 562 LYS 562 280 ?   ?   ?   A G n 
A 1 563 LYS 563 280 ?   ?   ?   A H n 
A 1 564 GLY 564 280 ?   ?   ?   A I n 
A 1 565 ILE 565 280 ?   ?   ?   A J n 
A 1 566 ILE 566 280 ?   ?   ?   A K n 
A 1 567 THR 567 280 ?   ?   ?   A L n 
A 1 568 ARG 568 280 ?   ?   ?   A M n 
A 1 569 ARG 569 280 ?   ?   ?   A N n 
A 1 570 PHE 570 280 ?   ?   ?   A O n 
A 1 571 MET 571 280 ?   ?   ?   A P n 
A 1 572 VAL 572 280 ?   ?   ?   A Q n 
A 1 573 THR 573 280 ?   ?   ?   A R n 
A 1 574 GLU 574 280 ?   ?   ?   A S n 
A 1 575 ILE 575 280 ?   ?   ?   A T n 
A 1 576 GLU 576 280 ?   ?   ?   A U n 
A 1 577 CYS 577 280 ?   ?   ?   A V n 
A 1 578 GLY 578 280 ?   ?   ?   A W n 
A 1 579 LYS 579 280 ?   ?   ?   A X n 
A 1 580 GLU 580 280 ?   ?   ?   A Y n 
A 1 581 ASP 581 280 ?   ?   ?   A Z n 
A 1 582 ASP 582 281 ?   ?   ?   A A n 
A 1 583 VAL 583 281 ?   ?   ?   A B n 
A 1 584 ILE 584 281 ?   ?   ?   A C n 
A 1 585 SER 585 281 ?   ?   ?   A D n 
A 1 586 GLU 586 281 ?   ?   ?   A E n 
A 1 587 THR 587 281 ?   ?   ?   A F n 
A 1 588 TYR 588 281 ?   ?   ?   A G n 
A 1 589 ARG 589 281 ?   ?   ?   A H n 
A 1 590 GLU 590 281 ?   ?   ?   A I n 
A 1 591 LYS 591 281 ?   ?   ?   A J n 
A 1 592 LEU 592 281 ?   ?   ?   A K n 
A 1 593 LYS 593 281 ?   ?   ?   A L n 
A 1 594 GLU 594 281 ?   ?   ?   A M n 
A 1 595 ALA 595 281 ?   ?   ?   A N n 
A 1 596 PHE 596 281 ?   ?   ?   A O n 
A 1 597 LYS 597 281 ?   ?   ?   A P n 
A 1 598 ARG 598 281 ?   ?   ?   A Q n 
A 1 599 PHE 599 281 ?   ?   ?   A R n 
A 1 600 ASP 600 281 ?   ?   ?   A S n 
A 1 601 THR 601 281 ?   ?   ?   A T n 
A 1 602 LYS 602 281 ?   ?   ?   A U n 
A 1 603 LYS 603 281 ?   ?   ?   A V n 
A 1 604 GLY 604 281 ?   ?   ?   A W n 
A 1 605 LYS 605 281 ?   ?   ?   A X n 
A 1 606 CYS 606 281 ?   ?   ?   A Y n 
A 1 607 LEU 607 281 ?   ?   ?   A Z n 
A 1 608 THR 608 282 ?   ?   ?   A A n 
A 1 609 ASP 609 282 ?   ?   ?   A B n 
A 1 610 LYS 610 282 ?   ?   ?   A C n 
A 1 611 GLU 611 282 ?   ?   ?   A D n 
A 1 612 ALA 612 282 ?   ?   ?   A E n 
A 1 613 LYS 613 282 ?   ?   ?   A F n 
A 1 614 GLU 614 282 ?   ?   ?   A G n 
A 1 615 ALA 615 282 ?   ?   ?   A H n 
A 1 616 GLY 616 282 ?   ?   ?   A I n 
A 1 617 PHE 617 282 ?   ?   ?   A J n 
A 1 618 CYS 618 282 ?   ?   ?   A K n 
A 1 619 ILE 619 282 ?   ?   ?   A L n 
A 1 620 LYS 620 282 ?   ?   ?   A M n 
A 1 621 LYS 621 282 ?   ?   ?   A N n 
A 1 622 ASN 622 282 ?   ?   ?   A O n 
A 1 623 GLU 623 282 ?   ?   ?   A P n 
A 1 624 LEU 624 282 ?   ?   ?   A Q n 
A 1 625 VAL 625 282 ?   ?   ?   A R n 
A 1 626 MET 626 282 ?   ?   ?   A S n 
A 1 627 SER 627 282 ?   ?   ?   A T n 
A 1 628 LEU 628 282 ?   ?   ?   A U n 
A 1 629 LYS 629 282 ?   ?   ?   A V n 
A 1 630 CYS 630 282 ?   ?   ?   A W n 
A 1 631 SER 631 282 ?   ?   ?   A X n 
A 1 632 ILE 632 282 ?   ?   ?   A Y n 
A 1 633 LYS 633 282 ?   ?   ?   A Z n 
A 1 634 GLY 634 283 ?   ?   ?   A A n 
A 1 635 THR 635 283 ?   ?   ?   A B n 
A 1 636 GLY 636 283 ?   ?   ?   A C n 
A 1 637 PRO 637 283 ?   ?   ?   A D n 
A 1 638 GLY 638 283 ?   ?   ?   A E n 
A 1 639 GLN 639 283 ?   ?   ?   A F n 
A 1 640 MET 640 283 ?   ?   ?   A G n 
A 1 641 ILE 641 283 ?   ?   ?   A H n 
A 1 642 ARG 642 283 ?   ?   ?   A I n 
A 1 643 ILE 643 283 ?   ?   ?   A J n 
A 1 644 ASN 644 283 ?   ?   ?   A K n 
A 1 645 ASN 645 283 ?   ?   ?   A L n 
A 1 646 ASN 646 283 ?   ?   ?   A M n 
A 1 647 VAL 647 283 ?   ?   ?   A N n 
A 1 648 PHE 648 283 ?   ?   ?   A O n 
A 1 649 LYS 649 283 ?   ?   ?   A P n 
A 1 650 THR 650 283 ?   ?   ?   A Q n 
A 1 651 ASN 651 283 ?   ?   ?   A R n 
A 1 652 VAL 652 283 ?   ?   ?   A S n 
A 1 653 HIS 653 283 ?   ?   ?   A T n 
A 1 654 ASN 654 283 ?   ?   ?   A U n 
A 1 655 VAL 655 283 ?   ?   ?   A V n 
A 1 656 GLY 656 283 ?   ?   ?   A W n 
A 1 657 VAL 657 283 ?   ?   ?   A X n 
A 1 658 ASP 658 283 ?   ?   ?   A Y n 
A 1 659 VAL 659 283 ?   ?   ?   A Z n 
A 1 660 TYR 660 284 ?   ?   ?   A A n 
A 1 661 LEU 661 284 ?   ?   ?   A B n 
A 1 662 ASP 662 284 ?   ?   ?   A C n 
A 1 663 GLU 663 284 ?   ?   ?   A D n 
A 1 664 LYS 664 284 ?   ?   ?   A E n 
A 1 665 GLY 665 284 ?   ?   ?   A F n 
A 1 666 LYS 666 284 ?   ?   ?   A G n 
A 1 667 LYS 667 284 ?   ?   ?   A H n 
A 1 668 LYS 668 284 ?   ?   ?   A I n 
A 1 669 ALA 669 284 ?   ?   ?   A J n 
A 1 670 TYR 670 284 ?   ?   ?   A K n 
A 1 671 GLU 671 284 ?   ?   ?   A L n 
A 1 672 ARG 672 284 ?   ?   ?   A M n 
A 1 673 LYS 673 284 ?   ?   ?   A N n 
A 1 674 ASN 674 284 ?   ?   ?   A O n 
A 1 675 PRO 675 284 ?   ?   ?   A P n 
A 1 676 ARG 676 284 ?   ?   ?   A Q n 
A 1 677 LEU 677 284 ?   ?   ?   A R n 
A 1 678 SER 678 284 ?   ?   ?   A S n 
A 1 679 LYS 679 284 ?   ?   ?   A T n 
A 1 680 HIS 680 284 ?   ?   ?   A U n 
A 1 681 PHE 681 284 ?   ?   ?   A V n 
A 1 682 ILE 682 284 ?   ?   ?   A W n 
A 1 683 GLU 683 284 ?   ?   ?   A X n 
A 1 684 PRO 684 284 ?   ?   ?   A Y n 
A 1 685 PRO 685 284 ?   ?   ?   A Z n 
A 1 686 PRO 686 285 ?   ?   ?   A A n 
A 1 687 GLN 687 285 ?   ?   ?   A B n 
A 1 688 PRO 688 285 ?   ?   ?   A C n 
A 1 689 ASN 689 285 ?   ?   ?   A D n 
A 1 690 GLY 690 285 ?   ?   ?   A E n 
A 1 691 ARG 691 285 ?   ?   ?   A F n 
A 1 692 VAL 692 285 ?   ?   ?   A G n 
A 1 693 SER 693 285 ?   ?   ?   A H n 
A 1 694 PHE 694 285 ?   ?   ?   A I n 
A 1 695 THR 695 285 ?   ?   ?   A J n 
A 1 696 LEU 696 285 ?   ?   ?   A K n 
A 1 697 LYS 697 285 ?   ?   ?   A L n 
A 1 698 ARG 698 285 ?   ?   ?   A M n 
A 1 699 ARG 699 285 ?   ?   ?   A N n 
A 1 700 ASP 700 285 ?   ?   ?   A O n 
A 1 701 MET 701 285 ?   ?   ?   A P n 
A 1 702 VAL 702 285 ?   ?   ?   A Q n 
A 1 703 THR 703 285 ?   ?   ?   A R n 
A 1 704 VAL 704 285 ?   ?   ?   A S n 
A 1 705 GLU 705 285 ?   ?   ?   A T n 
A 1 706 GLY 706 285 ?   ?   ?   A U n 
A 1 707 GLU 707 285 ?   ?   ?   A V n 
A 1 708 ASP 708 285 ?   ?   ?   A W n 
A 1 709 ALA 709 285 ?   ?   ?   A X n 
A 1 710 ILE 710 285 ?   ?   ?   A Y n 
A 1 711 TYR 711 285 ?   ?   ?   A Z n 
A 1 712 ARG 712 286 ?   ?   ?   A A n 
A 1 713 ILE 713 286 ?   ?   ?   A B n 
A 1 714 LYS 714 286 ?   ?   ?   A C n 
A 1 715 LYS 715 286 ?   ?   ?   A D n 
A 1 716 LEU 716 286 ?   ?   ?   A E n 
A 1 717 GLY 717 286 ?   ?   ?   A F n 
A 1 718 THR 718 286 ?   ?   ?   A G n 
A 1 719 SER 719 286 ?   ?   ?   A H n 
A 1 720 PRO 720 286 ?   ?   ?   A I n 
A 1 721 THR 721 286 ?   ?   ?   A J n 
A 1 722 ILE 722 286 ?   ?   ?   A K n 
A 1 723 GLU 723 286 ?   ?   ?   A L n 
A 1 724 ALA 724 286 ?   ?   ?   A M n 
A 1 725 VAL 725 286 ?   ?   ?   A N n 
A 1 726 VAL 726 286 ?   ?   ?   A O n 
A 1 727 GLY 727 286 ?   ?   ?   A P n 
A 1 728 SER 728 286 ?   ?   ?   A Q n 
A 1 729 ASP 729 286 ?   ?   ?   A R n 
A 1 730 GLY 730 286 ?   ?   ?   A S n 
A 1 731 LYS 731 286 ?   ?   ?   A T n 
A 1 732 THR 732 286 ?   ?   ?   A U n 
A 1 733 ARG 733 286 ?   ?   ?   A V n 
A 1 734 THR 734 286 ?   ?   ?   A W n 
A 1 735 VAL 735 286 ?   ?   ?   A X n 
A 1 736 SER 736 286 ?   ?   ?   A Y n 
A 1 737 ALA 737 286 ?   ?   ?   A Z n 
A 1 738 THR 738 287 ?   ?   ?   A A n 
A 1 739 LYS 739 287 ?   ?   ?   A B n 
A 1 740 LEU 740 287 ?   ?   ?   A C n 
A 1 741 THR 741 287 ?   ?   ?   A D n 
A 1 742 LYS 742 287 ?   ?   ?   A E n 
A 1 743 ALA 743 287 ?   ?   ?   A F n 
A 1 744 ASN 744 287 ?   ?   ?   A G n 
A 1 745 SER 745 287 ?   ?   ?   A H n 
A 1 746 ALA 746 287 ?   ?   ?   A I n 
A 1 747 GLU 747 287 ?   ?   ?   A J n 
A 1 748 ILE 748 287 ?   ?   ?   A K n 
A 1 749 GLU 749 287 ?   ?   ?   A L n 
A 1 750 GLN 750 287 ?   ?   ?   A M n 
A 1 751 SER 751 287 ?   ?   ?   A N n 
A 1 752 GLU 752 287 ?   ?   ?   A O n 
A 1 753 LYS 753 287 ?   ?   ?   A P n 
A 1 754 ASP 754 287 ?   ?   ?   A Q n 
A 1 755 ASN 755 287 ?   ?   ?   A R n 
A 1 756 LEU 756 287 ?   ?   ?   A S n 
A 1 757 LYS 757 287 ?   ?   ?   A T n 
A 1 758 ASP 758 287 ?   ?   ?   A U n 
A 1 759 ALA 759 287 ?   ?   ?   A V n 
A 1 760 VAL 760 287 ?   ?   ?   A W n 
A 1 761 LEU 761 287 ?   ?   ?   A X n 
A 1 762 ASP 762 287 ?   ?   ?   A Y n 
A 1 763 LYS 763 287 ?   ?   ?   A Z n 
A 1 764 ASN 764 288 ?   ?   ?   A A n 
A 1 765 ARG 765 288 ?   ?   ?   A B n 
A 1 766 ARG 766 288 ?   ?   ?   A C n 
A 1 767 GLU 767 288 ?   ?   ?   A D n 
A 1 768 GLU 768 288 ?   ?   ?   A E n 
A 1 769 VAL 769 288 ?   ?   ?   A F n 
A 1 770 LYS 770 288 ?   ?   ?   A G n 
A 1 771 SER 771 288 ?   ?   ?   A H n 
A 1 772 PHE 772 288 ?   ?   ?   A I n 
A 1 773 PHE 773 288 ?   ?   ?   A J n 
A 1 774 ARG 774 288 ?   ?   ?   A K n 
A 1 775 LYS 775 288 ?   ?   ?   A L n 
A 1 776 HIS 776 288 ?   ?   ?   A M n 
A 1 777 LYS 777 288 ?   ?   ?   A N n 
A 1 778 THR 778 288 ?   ?   ?   A O n 
A 1 779 ASP 779 288 ?   ?   ?   A P n 
A 1 780 GLU 780 288 ?   ?   ?   A Q n 
A 1 781 HIS 781 288 ?   ?   ?   A R n 
A 1 782 ILE 782 288 ?   ?   ?   A S n 
A 1 783 ARG 783 288 ?   ?   ?   A T n 
A 1 784 LYS 784 288 ?   ?   ?   A U n 
A 1 785 GLN 785 288 ?   ?   ?   A V n 
A 1 786 VAL 786 288 ?   ?   ?   A W n 
A 1 787 TYR 787 288 ?   ?   ?   A X n 
A 1 788 ASP 788 288 ?   ?   ?   A Y n 
A 1 789 ILE 789 288 ?   ?   ?   A Z n 
A 1 790 ALA 790 289 ?   ?   ?   A A n 
A 1 791 ASP 791 289 ?   ?   ?   A B n 
A 1 792 ASN 792 289 ?   ?   ?   A C n 
A 1 793 LYS 793 289 ?   ?   ?   A D n 
A 1 794 LEU 794 289 ?   ?   ?   A E n 
A 1 795 SER 795 289 ?   ?   ?   A F n 
A 1 796 GLY 796 289 ?   ?   ?   A G n 
A 1 797 ARG 797 289 ?   ?   ?   A H n 
A 1 798 THR 798 289 ?   ?   ?   A I n 
A 1 799 VAL 799 289 ?   ?   ?   A J n 
A 1 800 PHE 800 289 ?   ?   ?   A K n 
A 1 801 CYS 801 289 ?   ?   ?   A L n 
A 1 802 LYS 802 289 ?   ?   ?   A M n 
A 1 803 GLU 803 289 ?   ?   ?   A N n 
A 1 804 HIS 804 289 ?   ?   ?   A O n 
A 1 805 ILE 805 289 ?   ?   ?   A P n 
A 1 806 LEU 806 289 ?   ?   ?   A Q n 
A 1 807 SER 807 548 548 SER SER A . n 
A 1 808 ARG 808 549 549 ARG ARG A . n 
A 1 809 GLY 809 550 550 GLY GLY A . n 
A 1 810 SER 810 551 551 SER SER A . n 
A 1 811 ALA 811 552 552 ALA ALA A . n 
A 1 812 LEU 812 553 553 LEU LEU A . n 
A 1 813 HIS 813 554 554 HIS HIS A . n 
A 1 814 ASP 814 555 555 ASP ASP A . n 
A 1 815 ARG 815 556 556 ARG ARG A . n 
A 1 816 ASN 816 557 557 ASN ASN A . n 
A 1 817 PRO 817 558 558 PRO PRO A . n 
A 1 818 LEU 818 559 559 LEU LEU A . n 
A 1 819 SER 819 560 560 SER SER A . n 
A 1 820 TYR 820 561 561 TYR TYR A . n 
A 1 821 LYS 821 562 562 LYS LYS A . n 
A 1 822 LYS 822 563 563 LYS LYS A . n 
A 1 823 GLY 823 564 564 GLY GLY A . n 
A 1 824 ILE 824 565 565 ILE ILE A . n 
A 1 825 ILE 825 566 566 ILE ILE A . n 
A 1 826 THR 826 567 567 THR THR A . n 
A 1 827 ARG 827 568 568 ARG ARG A . n 
A 1 828 ARG 828 569 569 ARG ARG A . n 
A 1 829 PHE 829 570 570 PHE PHE A . n 
A 1 830 MET 830 571 571 MET MET A . n 
A 1 831 VAL 831 572 572 VAL VAL A . n 
A 1 832 THR 832 573 573 THR THR A . n 
A 1 833 GLU 833 574 574 GLU GLU A . n 
A 1 834 ILE 834 575 575 ILE ILE A . n 
A 1 835 GLU 835 576 576 GLU GLU A . n 
A 1 836 CYS 836 577 577 CYS CYS A . n 
A 1 837 GLY 837 578 578 GLY GLY A . n 
A 1 838 LYS 838 579 579 LYS LYS A . n 
A 1 839 GLU 839 580 580 GLU GLU A . n 
A 1 840 ASP 840 581 581 ASP ASP A . n 
A 1 841 ASP 841 582 582 ASP ASP A . n 
A 1 842 VAL 842 583 583 VAL VAL A . n 
A 1 843 ILE 843 584 584 ILE ILE A . n 
A 1 844 SER 844 585 585 SER SER A . n 
A 1 845 GLU 845 586 586 GLU GLU A . n 
A 1 846 THR 846 587 587 THR THR A . n 
A 1 847 TYR 847 588 588 TYR TYR A . n 
A 1 848 ARG 848 589 589 ARG ARG A . n 
A 1 849 GLU 849 590 590 GLU GLU A . n 
A 1 850 LYS 850 591 591 LYS LYS A . n 
A 1 851 LEU 851 592 592 LEU LEU A . n 
A 1 852 LYS 852 593 593 LYS LYS A . n 
A 1 853 GLU 853 594 594 GLU GLU A . n 
A 1 854 ALA 854 595 595 ALA ALA A . n 
A 1 855 PHE 855 596 596 PHE PHE A . n 
A 1 856 LYS 856 597 597 LYS LYS A . n 
A 1 857 ARG 857 598 598 ARG ARG A . n 
A 1 858 PHE 858 599 599 PHE PHE A . n 
A 1 859 ASP 859 600 600 ASP ASP A . n 
A 1 860 THR 860 601 601 THR THR A . n 
A 1 861 LYS 861 602 602 LYS LYS A . n 
A 1 862 LYS 862 603 603 LYS LYS A . n 
A 1 863 GLY 863 604 604 GLY GLY A . n 
A 1 864 LYS 864 605 605 LYS LYS A . n 
A 1 865 CYS 865 606 606 CYS CYS A . n 
A 1 866 LEU 866 607 607 LEU LEU A . n 
A 1 867 THR 867 608 608 THR THR A . n 
A 1 868 ASP 868 609 609 ASP ASP A . n 
A 1 869 LYS 869 610 610 LYS LYS A . n 
A 1 870 GLU 870 611 611 GLU GLU A . n 
A 1 871 ALA 871 612 612 ALA ALA A . n 
A 1 872 LYS 872 613 613 LYS LYS A . n 
A 1 873 GLU 873 614 614 GLU GLU A . n 
A 1 874 ALA 874 615 615 ALA ALA A . n 
A 1 875 GLY 875 616 616 GLY GLY A . n 
A 1 876 PHE 876 617 617 PHE PHE A . n 
A 1 877 CYS 877 618 618 CYS CYS A . n 
A 1 878 ILE 878 619 619 ILE ILE A . n 
A 1 879 LYS 879 620 620 LYS LYS A . n 
A 1 880 LYS 880 621 621 LYS LYS A . n 
A 1 881 ASN 881 622 622 ASN ASN A . n 
A 1 882 GLU 882 623 623 GLU GLU A . n 
A 1 883 LEU 883 624 624 LEU LEU A . n 
A 1 884 VAL 884 625 625 VAL VAL A . n 
A 1 885 MET 885 626 626 MET MET A . n 
A 1 886 SER 886 627 627 SER SER A . n 
A 1 887 LEU 887 628 628 LEU LEU A . n 
A 1 888 LYS 888 629 629 LYS LYS A . n 
A 1 889 CYS 889 630 630 CYS CYS A . n 
A 1 890 SER 890 631 631 SER SER A . n 
A 1 891 ILE 891 632 632 ILE ILE A . n 
A 1 892 LYS 892 633 633 LYS LYS A . n 
A 1 893 GLY 893 634 634 GLY GLY A . n 
A 1 894 THR 894 635 635 THR THR A . n 
A 1 895 GLY 895 636 636 GLY GLY A . n 
A 1 896 PRO 896 637 637 PRO PRO A . n 
A 1 897 GLY 897 638 638 GLY GLY A . n 
A 1 898 GLN 898 639 639 GLN GLN A . n 
A 1 899 MET 899 640 640 MET MET A . n 
A 1 900 ILE 900 641 641 ILE ILE A . n 
A 1 901 ARG 901 642 642 ARG ARG A . n 
A 1 902 ILE 902 643 643 ILE ILE A . n 
A 1 903 ASN 903 644 644 ASN ASN A . n 
A 1 904 ASN 904 645 645 ASN ASN A . n 
A 1 905 ASN 905 646 646 ASN ASN A . n 
A 1 906 VAL 906 647 647 VAL VAL A . n 
A 1 907 PHE 907 648 648 PHE PHE A . n 
A 1 908 LYS 908 649 649 LYS LYS A . n 
A 1 909 THR 909 650 650 THR THR A . n 
A 1 910 ASN 910 651 651 ASN ASN A . n 
A 1 911 VAL 911 652 652 VAL VAL A . n 
A 1 912 HIS 912 653 653 HIS HIS A . n 
A 1 913 ASN 913 654 654 ASN ASN A . n 
A 1 914 VAL 914 655 655 VAL VAL A . n 
A 1 915 UNK 915 656 ?   ?   ?   A . n 
A 1 916 UNK 916 657 ?   ?   ?   A . n 
A 1 917 UNK 917 658 ?   ?   ?   A . n 
A 1 918 UNK 918 659 ?   ?   ?   A . n 
A 1 919 UNK 919 660 ?   ?   ?   A . n 
A 1 920 UNK 920 661 ?   ?   ?   A . n 
A 1 921 UNK 921 662 ?   ?   ?   A . n 
A 1 922 UNK 922 663 ?   ?   ?   A . n 
A 1 923 UNK 923 664 ?   ?   ?   A . n 
A 1 924 UNK 924 665 ?   ?   ?   A . n 
A 1 925 UNK 925 666 ?   ?   ?   A . n 
A 1 926 UNK 926 667 ?   ?   ?   A . n 
A 1 927 UNK 927 668 ?   ?   ?   A . n 
A 1 928 UNK 928 669 ?   ?   ?   A . n 
A 1 929 UNK 929 670 ?   ?   ?   A . n 
A 1 930 UNK 930 671 ?   ?   ?   A . n 
A 1 931 ARG 931 672 672 ARG ARG A . n 
A 1 932 LYS 932 673 673 LYS LYS A . n 
A 1 933 ASN 933 674 674 ASN ASN A . n 
A 1 934 PRO 934 675 675 PRO PRO A . n 
A 1 935 ARG 935 676 676 ARG ARG A . n 
A 1 936 LEU 936 677 677 LEU LEU A . n 
A 1 937 SER 937 678 678 SER SER A . n 
A 1 938 LYS 938 679 679 LYS LYS A . n 
A 1 939 HIS 939 680 680 HIS HIS A . n 
A 1 940 PHE 940 681 681 PHE PHE A . n 
A 1 941 ILE 941 682 682 ILE ILE A . n 
A 1 942 GLU 942 683 683 GLU GLU A . n 
B 2 1   G   1   1   ?   ?   ?   B . n 
B 2 2   A   2   2   ?   ?   ?   B . n 
B 2 3   C   3   3   ?   ?   ?   B . n 
B 2 4   G   4   4   ?   ?   ?   B . n 
B 2 5   C   5   5   ?   ?   ?   B . n 
B 2 6   A   6   6   ?   ?   ?   B . n 
B 2 7   U   7   7   ?   ?   ?   B . n 
B 2 8   A   8   8   ?   ?   ?   B . n 
B 2 9   A   9   9   ?   ?   ?   B . n 
B 2 10  A   10  10  10  A   A   B . n 
B 2 11  G   11  11  11  G   G   B . n 
B 2 12  A   12  12  12  A   A   B . n 
B 2 13  U   13  13  13  U   U   B . n 
B 2 14  G   14  14  14  G   G   B . n 
B 2 15  A   15  15  15  A   A   B . n 
B 2 16  G   16  16  16  G   G   B . n 
B 2 17  A   17  17  17  A   A   B . n 
B 2 18  C   18  18  18  C   C   B . n 
B 2 19  G   19  19  19  G   G   B . n 
B 2 20  C   20  20  20  C   C   B . n 
B 2 21  G   21  21  21  G   G   B . n 
B 2 22  U   22  22  22  U   U   B . n 
B 2 23  U   23  23  23  U   U   B . n 
B 2 24  A   24  24  24  A   A   B . n 
B 2 25  C   25  25  25  C   C   B . n 
B 2 26  A   26  26  26  A   A   B . n 
B 2 27  G   27  27  27  G   G   B . n 
B 2 28  U   28  28  28  U   U   B . n 
B 2 29  U   29  29  29  U   U   B . n 
B 2 30  A   30  30  30  A   A   B . n 
B 2 31  A   31  31  31  A   A   B . n 
B 2 32  G   32  32  32  G   G   B . n 
B 2 33  G   33  33  33  G   G   B . n 
B 2 34  C   34  34  34  C   C   B . n 
B 2 35  U   35  35  35  U   U   B . n 
B 2 36  C   36  36  36  C   C   B . n 
B 2 37  U   37  37  37  U   U   B . n 
B 2 38  G   38  38  38  G   G   B . n 
B 2 39  A   39  39  39  A   A   B . n 
B 2 40  A   40  40  40  A   A   B . n 
B 2 41  A   41  41  41  A   A   B . n 
B 2 42  A   42  42  42  A   A   B . n 
B 2 43  G   43  43  43  G   G   B . n 
B 2 44  A   44  44  44  A   A   B . n 
B 2 45  G   45  45  45  G   G   B . n 
B 2 46  C   46  46  46  C   C   B . n 
B 2 47  C   47  47  47  C   C   B . n 
B 2 48  U   48  48  48  U   U   B . n 
B 2 49  U   49  49  49  U   U   B . n 
B 2 50  A   50  50  50  A   A   B . n 
B 2 51  A   51  51  51  A   A   B . n 
B 2 52  U   52  52  52  U   U   B . n 
B 2 53  U   53  53  53  U   U   B . n 
B 2 54  G   54  54  54  G   G   B . n 
B 2 55  U   55  55  55  U   U   B . n 
B 2 56  A   56  56  56  A   A   B . n 
B 2 57  A   57  57  57  A   A   B . n 
B 2 58  A   58  58  58  A   A   B . n 
B 2 59  A   59  59  59  A   A   B . n 
B 2 60  C   60  60  60  C   C   B . n 
B 2 61  G   61  61  61  G   G   B . n 
B 2 62  C   62  62  62  C   C   B . n 
B 2 63  C   63  63  63  C   C   B . n 
B 2 64  U   64  64  64  U   U   B . n 
B 2 65  A   65  65  65  A   A   B . n 
B 2 66  U   66  66  66  U   U   B . n 
B 2 67  A   67  67  67  A   A   B . n 
B 2 68  C   68  68  68  C   C   B . n 
B 2 69  A   69  69  69  A   A   B . n 
B 2 70  G   70  70  70  G   G   B . n 
B 2 71  U   71  71  71  U   U   B . n 
B 2 72  G   72  72  72  G   G   B . n 
B 2 73  A   73  73  73  A   A   B . n 
B 2 74  A   74  74  74  A   A   B . n 
B 2 75  G   75  75  75  G   G   B . n 
B 2 76  G   76  76  76  G   G   B . n 
B 2 77  G   77  77  77  G   G   B . n 
B 2 78  A   78  78  78  A   A   B . n 
B 2 79  U   79  79  79  U   U   B . n 
B 2 80  A   80  80  80  A   A   B . n 
B 2 81  U   81  81  81  U   U   B . n 
B 2 82  A   82  82  82  A   A   B . n 
B 2 83  C   83  83  83  C   C   B . n 
B 2 84  G   84  84  84  G   G   B . n 
B 2 85  C   85  85  85  C   C   B . n 
B 2 86  U   86  86  86  U   U   B . n 
B 2 87  U   87  87  87  U   U   B . n 
B 2 88  G   88  88  88  G   G   B . n 
B 2 89  G   89  89  89  G   G   B . n 
B 2 90  G   90  90  90  G   G   B . n 
B 2 91  U   91  91  91  U   U   B . n 
B 2 92  U   92  92  92  U   U   B . n 
B 2 93  U   93  93  93  U   U   B . n 
B 2 94  G   94  94  94  G   G   B . n 
B 2 95  U   95  95  95  U   U   B . n 
B 2 96  C   96  96  96  C   C   B . n 
B 2 97  C   97  97  97  C   C   B . n 
B 2 98  A   98  98  98  A   A   B . n 
B 2 99  G   99  99  99  G   G   B . n 
B 2 100 C   100 100 100 C   C   B . n 
B 2 101 C   101 101 101 C   C   B . n 
B 2 102 U   102 102 102 U   U   B . n 
B 2 103 G   103 103 103 G   G   B . n 
B 2 104 A   104 104 104 A   A   B . n 
B 2 105 G   105 105 105 G   G   B . n 
B 2 106 C   106 106 106 C   C   B . n 
B 2 107 C   107 107 107 C   C   B . n 
B 2 108 U   108 108 108 U   U   B . n 
B 2 109 C   109 109 109 C   C   B . n 
B 2 110 U   110 110 110 U   U   B . n 
B 2 111 A   111 111 111 A   A   B . n 
B 2 112 U   112 112 112 U   U   B . n 
B 2 113 G   113 113 113 G   G   B . n 
B 2 114 C   114 114 114 C   C   B . n 
B 2 115 C   115 115 115 C   C   B . n 
B 2 116 A   116 116 116 A   A   B . n 
B 2 117 G   117 117 117 G   G   B . n 
B 2 118 A   118 118 118 A   A   B . n 
B 2 119 A   119 119 119 A   A   B . n 
B 2 120 A   120 120 120 A   A   B . n 
B 2 121 U   121 121 121 U   U   B . n 
B 2 122 G   122 122 122 G   G   B . n 
B 2 123 G   123 123 123 G   G   B . n 
B 2 124 C   124 124 124 C   C   B . n 
B 2 125 G   125 125 125 G   G   B . n 
B 2 126 C   126 126 126 C   C   B . n 
B 2 127 C   127 127 127 C   C   B . n 
B 2 128 U   128 128 128 U   U   B . n 
B 2 129 U   129 129 129 U   U   B . n 
B 2 130 C   130 130 130 C   C   B . n 
B 2 131 A   131 131 131 A   A   B . n 
B 2 132 U   132 132 132 U   U   B . n 
B 2 133 C   133 133 133 C   C   B . n 
B 2 134 G   134 134 134 G   G   B . n 
B 2 135 U   135 135 135 U   U   B . n 
B 2 136 G   136 136 136 G   G   B . n 
B 2 137 G   137 137 137 G   G   B . n 
B 2 138 G   138 138 138 G   G   B . n 
B 2 139 U   139 139 139 U   U   B . n 
B 2 140 U   140 140 140 U   U   B . n 
B 2 141 A   141 141 141 A   A   B . n 
B 2 142 G   142 142 142 G   G   B . n 
B 2 143 G   143 143 143 G   G   B . n 
B 2 144 A   144 144 144 A   A   B . n 
B 2 145 C   145 145 145 C   C   B . n 
B 2 146 A   146 146 146 A   A   B . n 
B 2 147 U   147 147 ?   ?   ?   B . n 
B 2 148 U   148 148 ?   ?   ?   B . n 
B 2 149 U   149 149 ?   ?   ?   B . n 
B 2 150 A   150 150 ?   ?   ?   B . n 
B 2 151 A   151 151 ?   ?   ?   B . n 
B 2 152 U   152 152 ?   ?   ?   B . n 
B 2 153 U   153 153 ?   ?   ?   B . n 
B 2 154 U   154 154 ?   ?   ?   B . n 
B 2 155 U   155 155 ?   ?   ?   B . n 
B 2 156 U   156 156 ?   ?   ?   B . n 
B 2 157 U   157 157 ?   ?   ?   B . n 
B 2 158 U   158 158 ?   ?   ?   B . n 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 A MET 100 ? CG  ? A MET 100 CG  
2  1 Y 1 A MET 100 ? SD  ? A MET 100 SD  
3  1 Y 1 A MET 100 ? CE  ? A MET 100 CE  
4  1 Y 1 A GLU 103 ? CG  ? A GLU 103 CG  
5  1 Y 1 A GLU 103 ? CD  ? A GLU 103 CD  
6  1 Y 1 A GLU 103 ? OE1 ? A GLU 103 OE1 
7  1 Y 1 A GLU 103 ? OE2 ? A GLU 103 OE2 
8  1 Y 1 A GLU 129 ? CG  ? A GLU 129 CG  
9  1 Y 1 A GLU 129 ? CD  ? A GLU 129 CD  
10 1 Y 1 A GLU 129 ? OE1 ? A GLU 129 OE1 
11 1 Y 1 A GLU 129 ? OE2 ? A GLU 129 OE2 
12 1 Y 1 A ARG 132 ? CG  ? A ARG 132 CG  
13 1 Y 1 A ARG 132 ? CD  ? A ARG 132 CD  
14 1 Y 1 A ARG 132 ? NE  ? A ARG 132 NE  
15 1 Y 1 A ARG 132 ? CZ  ? A ARG 132 CZ  
16 1 Y 1 A ARG 132 ? NH1 ? A ARG 132 NH1 
17 1 Y 1 A ARG 132 ? NH2 ? A ARG 132 NH2 
18 1 Y 1 A LYS 138 ? CG  ? A LYS 138 CG  
19 1 Y 1 A LYS 138 ? CD  ? A LYS 138 CD  
20 1 Y 1 A LYS 138 ? CE  ? A LYS 138 CE  
21 1 Y 1 A LYS 138 ? NZ  ? A LYS 138 NZ  
22 1 Y 1 A GLU 139 ? CG  ? A GLU 139 CG  
23 1 Y 1 A GLU 139 ? CD  ? A GLU 139 CD  
24 1 Y 1 A GLU 139 ? OE1 ? A GLU 139 OE1 
25 1 Y 1 A GLU 139 ? OE2 ? A GLU 139 OE2 
26 1 Y 1 A LYS 159 ? CG  ? A LYS 159 CG  
27 1 Y 1 A LYS 159 ? CD  ? A LYS 159 CD  
28 1 Y 1 A LYS 159 ? CE  ? A LYS 159 CE  
29 1 Y 1 A LYS 159 ? NZ  ? A LYS 159 NZ  
30 1 Y 1 A PHE 235 ? CG  ? A PHE 235 CG  
31 1 Y 1 A PHE 235 ? CD1 ? A PHE 235 CD1 
32 1 Y 1 A PHE 235 ? CD2 ? A PHE 235 CD2 
33 1 Y 1 A PHE 235 ? CE1 ? A PHE 235 CE1 
34 1 Y 1 A PHE 235 ? CE2 ? A PHE 235 CE2 
35 1 Y 1 A PHE 235 ? CZ  ? A PHE 235 CZ  
36 1 Y 1 A LYS 240 ? CG  ? A LYS 240 CG  
37 1 Y 1 A LYS 240 ? CD  ? A LYS 240 CD  
38 1 Y 1 A LYS 240 ? CE  ? A LYS 240 CE  
39 1 Y 1 A LYS 240 ? NZ  ? A LYS 240 NZ  
40 1 Y 1 A ARG 246 ? CG  ? A ARG 246 CG  
41 1 Y 1 A ARG 246 ? CD  ? A ARG 246 CD  
42 1 Y 1 A ARG 246 ? NE  ? A ARG 246 NE  
43 1 Y 1 A ARG 246 ? CZ  ? A ARG 246 CZ  
44 1 Y 1 A ARG 246 ? NH1 ? A ARG 246 NH1 
45 1 Y 1 A ARG 246 ? NH2 ? A ARG 246 NH2 
46 1 Y 1 A ASP 251 ? CG  ? A ASP 251 CG  
47 1 Y 1 A ASP 251 ? OD1 ? A ASP 251 OD1 
48 1 Y 1 A ASP 251 ? OD2 ? A ASP 251 OD2 
49 1 Y 1 A LYS 256 ? CG  ? A LYS 256 CG  
50 1 Y 1 A LYS 256 ? CD  ? A LYS 256 CD  
51 1 Y 1 A LYS 256 ? CE  ? A LYS 256 CE  
52 1 Y 1 A LYS 256 ? NZ  ? A LYS 256 NZ  
53 1 Y 1 A LYS 593 ? CG  ? A LYS 852 CG  
54 1 Y 1 A LYS 593 ? CD  ? A LYS 852 CD  
55 1 Y 1 A LYS 593 ? CE  ? A LYS 852 CE  
56 1 Y 1 A LYS 593 ? NZ  ? A LYS 852 NZ  
57 1 Y 1 A PHE 596 ? CG  ? A PHE 855 CG  
58 1 Y 1 A PHE 596 ? CD1 ? A PHE 855 CD1 
59 1 Y 1 A PHE 596 ? CD2 ? A PHE 855 CD2 
60 1 Y 1 A PHE 596 ? CE1 ? A PHE 855 CE1 
61 1 Y 1 A PHE 596 ? CE2 ? A PHE 855 CE2 
62 1 Y 1 A PHE 596 ? CZ  ? A PHE 855 CZ  
63 1 Y 1 A LYS 597 ? CG  ? A LYS 856 CG  
64 1 Y 1 A LYS 597 ? CD  ? A LYS 856 CD  
65 1 Y 1 A LYS 597 ? CE  ? A LYS 856 CE  
66 1 Y 1 A LYS 597 ? NZ  ? A LYS 856 NZ  
67 1 Y 1 A ASP 600 ? CG  ? A ASP 859 CG  
68 1 Y 1 A ASP 600 ? OD1 ? A ASP 859 OD1 
69 1 Y 1 A ASP 600 ? OD2 ? A ASP 859 OD2 
70 1 Y 1 A LYS 603 ? CG  ? A LYS 862 CG  
71 1 Y 1 A LYS 603 ? CD  ? A LYS 862 CD  
72 1 Y 1 A LYS 603 ? CE  ? A LYS 862 CE  
73 1 Y 1 A LYS 603 ? NZ  ? A LYS 862 NZ  
74 1 Y 1 A THR 608 ? OG1 ? A THR 867 OG1 
75 1 Y 1 A THR 608 ? CG2 ? A THR 867 CG2 
76 1 Y 1 A ASP 609 ? CG  ? A ASP 868 CG  
77 1 Y 1 A ASP 609 ? OD1 ? A ASP 868 OD1 
78 1 Y 1 A ASP 609 ? OD2 ? A ASP 868 OD2 
79 1 Y 1 A LYS 610 ? CG  ? A LYS 869 CG  
80 1 Y 1 A LYS 610 ? CD  ? A LYS 869 CD  
81 1 Y 1 A LYS 610 ? CE  ? A LYS 869 CE  
82 1 Y 1 A LYS 610 ? NZ  ? A LYS 869 NZ  
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8W2S 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8W2S 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8W2S 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.entry_id                                 8W2S 
_refine.pdbx_diffrn_id                           ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             ? 
_refine.ls_d_res_high                            . 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.B_iso_mean                               ? 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_ksol                 ? 
_refine.solvent_model_param_bsol                 ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.details                                  ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.004  ? 6091 ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.847  ? 8863 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 20.653 ? 2368 ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.049  ? 1089 ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.006  ? 627  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     8W2S 
_struct.title                        'Cas9d Effector:sgRNA Binary Complex' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8W2S 
_struct_keywords.text            'CRISPR-Cas9, Endonuclease, Binary Complex, Effector, sgRNA, IMMUNE SYSTEM-RNA complex' 
_struct_keywords.pdbx_keywords   'IMMUNE SYSTEM/RNA' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 PDB 8W2S 8W2S ? 1 ? 1 
2 PDB 8W2S 8W2S ? 2 ? 1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8W2S A 1 ? 942 ? 8W2S 1 ? 683 ? 1 683 
2 2 8W2S B 1 ? 158 ? 8W2S 1 ? 158 ? 1 158 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 LEU A 44  ? GLY A 75  ? LEU A 44  GLY A 75  1 ? 32 
HELX_P HELX_P2  AA2 THR A 80  ? HIS A 91  ? THR A 80  HIS A 91  1 ? 12 
HELX_P HELX_P3  AA3 TYR A 95  ? ASP A 99  ? TYR A 95  ASP A 99  5 ? 5  
HELX_P HELX_P4  AA4 THR A 105 ? GLU A 110 ? THR A 105 GLU A 110 1 ? 6  
HELX_P HELX_P5  AA5 ASP A 113 ? ARG A 132 ? ASP A 113 ARG A 132 1 ? 20 
HELX_P HELX_P6  AA6 HIS A 136 ? GLY A 151 ? HIS A 136 GLY A 151 1 ? 16 
HELX_P HELX_P7  AA7 THR A 154 ? LYS A 167 ? THR A 154 LYS A 167 1 ? 14 
HELX_P HELX_P8  AA8 VAL A 197 ? ARG A 207 ? VAL A 197 ARG A 207 1 ? 11 
HELX_P HELX_P9  AA9 GLU A 212 ? ASP A 225 ? GLU A 212 ASP A 225 1 ? 14 
HELX_P HELX_P10 AB1 ARG A 228 ? HIS A 239 ? ARG A 228 HIS A 239 1 ? 12 
HELX_P HELX_P11 AB2 ASP A 242 ? ASP A 254 ? ASP A 242 ASP A 254 1 ? 13 
HELX_P HELX_P12 AB3 CYS A 264 ? ILE A 268 ? CYS A 264 ILE A 268 5 ? 5  
HELX_P HELX_P13 AB4 GLU A 835 ? VAL A 842 ? GLU A 576 VAL A 583 5 ? 8  
HELX_P HELX_P14 AB5 SER A 844 ? PHE A 858 ? SER A 585 PHE A 599 1 ? 15 
HELX_P HELX_P15 AB6 THR A 867 ? GLU A 873 ? THR A 608 GLU A 614 1 ? 7  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
hydrog1   hydrog ? ? B G 21  N1 ? ? ? 1_555 B A 58  N1 ? ? B G 21  B A 58  1_555 ? ? ? ? ? ? TYPE_8_PAIR             ? ? ? 
hydrog2   hydrog ? ? B G 21  O6 ? ? ? 1_555 B A 58  N6 ? ? B G 21  B A 58  1_555 ? ? ? ? ? ? TYPE_8_PAIR             ? ? ? 
hydrog3   hydrog ? ? B U 22  N3 ? ? ? 1_555 B A 57  N1 ? ? B U 22  B A 57  1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog4   hydrog ? ? B U 22  O4 ? ? ? 1_555 B A 57  N6 ? ? B U 22  B A 57  1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog5   hydrog ? ? B U 23  N3 ? ? ? 1_555 B A 56  N1 ? ? B U 23  B A 56  1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog6   hydrog ? ? B U 23  O4 ? ? ? 1_555 B A 56  N6 ? ? B U 23  B A 56  1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog7   hydrog ? ? B A 24  N1 ? ? ? 1_555 B U 55  N3 ? ? B A 24  B U 55  1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog8   hydrog ? ? B A 24  N6 ? ? ? 1_555 B U 55  O4 ? ? B A 24  B U 55  1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog9   hydrog ? ? B C 25  N3 ? ? ? 1_555 B G 54  N1 ? ? B C 25  B G 54  1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog10  hydrog ? ? B C 25  N4 ? ? ? 1_555 B G 54  O6 ? ? B C 25  B G 54  1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog11  hydrog ? ? B C 25  O2 ? ? ? 1_555 B G 54  N2 ? ? B C 25  B G 54  1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog12  hydrog ? ? B A 26  N1 ? ? ? 1_555 B U 53  N3 ? ? B A 26  B U 53  1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog13  hydrog ? ? B A 26  N6 ? ? ? 1_555 B U 53  O4 ? ? B A 26  B U 53  1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog14  hydrog ? ? B G 27  N1 ? ? ? 1_555 B U 52  O2 ? ? B G 27  B U 52  1_555 ? ? ? ? ? ? TYPE_28_PAIR            ? ? ? 
hydrog15  hydrog ? ? B G 27  O6 ? ? ? 1_555 B U 52  N3 ? ? B G 27  B U 52  1_555 ? ? ? ? ? ? TYPE_28_PAIR            ? ? ? 
hydrog16  hydrog ? ? B U 28  N3 ? ? ? 1_555 B A 51  N1 ? ? B U 28  B A 51  1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog17  hydrog ? ? B U 28  O4 ? ? ? 1_555 B A 51  N6 ? ? B U 28  B A 51  1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog18  hydrog ? ? B U 29  N3 ? ? ? 1_555 B A 50  N1 ? ? B U 29  B A 50  1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog19  hydrog ? ? B U 29  O4 ? ? ? 1_555 B A 50  N6 ? ? B U 29  B A 50  1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog20  hydrog ? ? B A 30  N1 ? ? ? 1_555 B U 49  N3 ? ? B A 30  B U 49  1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog21  hydrog ? ? B A 30  N6 ? ? ? 1_555 B U 49  O4 ? ? B A 30  B U 49  1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog22  hydrog ? ? B A 31  N1 ? ? ? 1_555 B U 48  N3 ? ? B A 31  B U 48  1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog23  hydrog ? ? B A 31  N6 ? ? ? 1_555 B U 48  O4 ? ? B A 31  B U 48  1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog24  hydrog ? ? B G 32  N1 ? ? ? 1_555 B C 47  N3 ? ? B G 32  B C 47  1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog25  hydrog ? ? B G 32  N2 ? ? ? 1_555 B C 47  O2 ? ? B G 32  B C 47  1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog26  hydrog ? ? B G 32  O6 ? ? ? 1_555 B C 47  N4 ? ? B G 32  B C 47  1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog27  hydrog ? ? B G 33  N1 ? ? ? 1_555 B C 46  N3 ? ? B G 33  B C 46  1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog28  hydrog ? ? B G 33  N2 ? ? ? 1_555 B C 46  O2 ? ? B G 33  B C 46  1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog29  hydrog ? ? B G 33  O6 ? ? ? 1_555 B C 46  N4 ? ? B G 33  B C 46  1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog30  hydrog ? ? B C 34  N3 ? ? ? 1_555 B G 45  N1 ? ? B C 34  B G 45  1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog31  hydrog ? ? B C 34  N4 ? ? ? 1_555 B G 45  O6 ? ? B C 34  B G 45  1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog32  hydrog ? ? B C 34  O2 ? ? ? 1_555 B G 45  N2 ? ? B C 34  B G 45  1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog33  hydrog ? ? B U 35  N3 ? ? ? 1_555 B A 44  N1 ? ? B U 35  B A 44  1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog34  hydrog ? ? B U 35  O4 ? ? ? 1_555 B A 44  N6 ? ? B U 35  B A 44  1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog35  hydrog ? ? B C 36  N3 ? ? ? 1_555 B G 43  N1 ? ? B C 36  B G 43  1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog36  hydrog ? ? B C 36  N4 ? ? ? 1_555 B G 43  O6 ? ? B C 36  B G 43  1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog37  hydrog ? ? B C 36  O2 ? ? ? 1_555 B G 43  N2 ? ? B C 36  B G 43  1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog38  hydrog ? ? B U 37  N3 ? ? ? 1_555 B A 42  N1 ? ? B U 37  B A 42  1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog39  hydrog ? ? B U 37  O4 ? ? ? 1_555 B A 42  N6 ? ? B U 37  B A 42  1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog40  hydrog ? ? B G 38  N2 ? ? ? 1_555 B A 41  N7 ? ? B G 38  B A 41  1_555 ? ? ? ? ? ? 'G-A MISPAIR'           ? ? ? 
hydrog41  hydrog ? ? B C 60  N4 ? ? ? 1_555 B U 140 O2 ? ? B C 60  B U 140 1_555 ? ? ? ? ? ? 'C-U MISPAIR'           ? ? ? 
hydrog42  hydrog ? ? B G 61  N1 ? ? ? 1_555 B U 139 O2 ? ? B G 61  B U 139 1_555 ? ? ? ? ? ? TYPE_28_PAIR            ? ? ? 
hydrog43  hydrog ? ? B G 61  O6 ? ? ? 1_555 B U 139 N3 ? ? B G 61  B U 139 1_555 ? ? ? ? ? ? TYPE_28_PAIR            ? ? ? 
hydrog44  hydrog ? ? B C 62  N3 ? ? ? 1_555 B G 138 N1 ? ? B C 62  B G 138 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog45  hydrog ? ? B C 62  N4 ? ? ? 1_555 B G 138 O6 ? ? B C 62  B G 138 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog46  hydrog ? ? B C 62  O2 ? ? ? 1_555 B G 138 N2 ? ? B C 62  B G 138 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog47  hydrog ? ? B C 63  N3 ? ? ? 1_555 B G 137 N1 ? ? B C 63  B G 137 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog48  hydrog ? ? B C 63  N4 ? ? ? 1_555 B G 137 O6 ? ? B C 63  B G 137 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog49  hydrog ? ? B C 63  O2 ? ? ? 1_555 B G 137 N2 ? ? B C 63  B G 137 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog50  hydrog ? ? B U 64  N3 ? ? ? 1_555 B G 136 O6 ? ? B U 64  B G 136 1_555 ? ? ? ? ? ? TYPE_28_PAIR            ? ? ? 
hydrog51  hydrog ? ? B U 64  O2 ? ? ? 1_555 B G 136 N1 ? ? B U 64  B G 136 1_555 ? ? ? ? ? ? TYPE_28_PAIR            ? ? ? 
hydrog52  hydrog ? ? B A 67  N1 ? ? ? 1_555 B U 135 N3 ? ? B A 67  B U 135 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog53  hydrog ? ? B A 67  N6 ? ? ? 1_555 B U 135 O4 ? ? B A 67  B U 135 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog54  hydrog ? ? B C 68  N3 ? ? ? 1_555 B G 134 N1 ? ? B C 68  B G 134 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog55  hydrog ? ? B C 68  N4 ? ? ? 1_555 B G 134 O6 ? ? B C 68  B G 134 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog56  hydrog ? ? B C 68  O2 ? ? ? 1_555 B G 134 N2 ? ? B C 68  B G 134 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog57  hydrog ? ? B G 70  N1 ? ? ? 1_555 B U 132 O2 ? ? B G 70  B U 132 1_555 ? ? ? ? ? ? TYPE_28_PAIR            ? ? ? 
hydrog58  hydrog ? ? B G 70  O6 ? ? ? 1_555 B U 132 N3 ? ? B G 70  B U 132 1_555 ? ? ? ? ? ? TYPE_28_PAIR            ? ? ? 
hydrog59  hydrog ? ? B U 71  N3 ? ? ? 1_555 B A 131 N1 ? ? B U 71  B A 131 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog60  hydrog ? ? B U 71  O4 ? ? ? 1_555 B A 131 N6 ? ? B U 71  B A 131 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog61  hydrog ? ? B G 72  N1 ? ? ? 1_555 B C 130 N3 ? ? B G 72  B C 130 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog62  hydrog ? ? B G 72  N2 ? ? ? 1_555 B C 130 O2 ? ? B G 72  B C 130 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog63  hydrog ? ? B G 72  O6 ? ? ? 1_555 B C 130 N4 ? ? B G 72  B C 130 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog64  hydrog ? ? B A 73  N1 ? ? ? 1_555 B U 129 N3 ? ? B A 73  B U 129 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog65  hydrog ? ? B A 73  N6 ? ? ? 1_555 B U 129 O4 ? ? B A 73  B U 129 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog66  hydrog ? ? B A 74  N1 ? ? ? 1_555 B U 128 N3 ? ? B A 74  B U 128 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog67  hydrog ? ? B A 74  N6 ? ? ? 1_555 B U 128 O4 ? ? B A 74  B U 128 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog68  hydrog ? ? B G 75  N1 ? ? ? 1_555 B C 127 N3 ? ? B G 75  B C 127 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog69  hydrog ? ? B G 75  N2 ? ? ? 1_555 B C 127 O2 ? ? B G 75  B C 127 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog70  hydrog ? ? B G 75  O6 ? ? ? 1_555 B C 127 N4 ? ? B G 75  B C 127 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog71  hydrog ? ? B G 76  N1 ? ? ? 1_555 B C 126 N3 ? ? B G 76  B C 126 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog72  hydrog ? ? B G 76  N2 ? ? ? 1_555 B C 126 O2 ? ? B G 76  B C 126 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog73  hydrog ? ? B G 76  O6 ? ? ? 1_555 B C 126 N4 ? ? B G 76  B C 126 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog74  hydrog ? ? B G 77  N2 ? ? ? 1_555 B G 125 O6 ? ? B G 77  B G 125 1_555 ? ? ? ? ? ? 'G-G MISPAIR'           ? ? ? 
hydrog75  hydrog ? ? B A 80  N1 ? ? ? 1_555 B U 112 N3 ? ? B A 80  B U 112 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog76  hydrog ? ? B A 80  N6 ? ? ? 1_555 B U 112 O4 ? ? B A 80  B U 112 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog77  hydrog ? ? B U 81  N3 ? ? ? 1_555 B A 111 N1 ? ? B U 81  B A 111 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog78  hydrog ? ? B U 81  O4 ? ? ? 1_555 B A 111 N6 ? ? B U 81  B A 111 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog79  hydrog ? ? B A 82  N6 ? ? ? 1_555 B C 107 N3 ? ? B A 82  B C 107 1_555 ? ? ? ? ? ? TYPE_25_PAIR            ? ? ? 
hydrog80  hydrog ? ? B A 82  N7 ? ? ? 1_555 B C 107 N4 ? ? B A 82  B C 107 1_555 ? ? ? ? ? ? TYPE_25_PAIR            ? ? ? 
hydrog81  hydrog ? ? B A 82  N1 ? ? ? 1_555 B U 110 N3 ? ? B A 82  B U 110 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog82  hydrog ? ? B A 82  N6 ? ? ? 1_555 B U 110 O4 ? ? B A 82  B U 110 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog83  hydrog ? ? B G 84  N1 ? ? ? 1_555 B C 106 N3 ? ? B G 84  B C 106 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog84  hydrog ? ? B G 84  N2 ? ? ? 1_555 B C 106 O2 ? ? B G 84  B C 106 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog85  hydrog ? ? B G 84  O6 ? ? ? 1_555 B C 106 N4 ? ? B G 84  B C 106 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog86  hydrog ? ? B G 84  N2 ? ? ? 1_555 B U 108 O4 ? ? B G 84  B U 108 1_555 ? ? ? ? ? ? 'G-U MISPAIR'           ? ? ? 
hydrog87  hydrog ? ? B G 84  N3 ? ? ? 1_555 B C 109 N4 ? ? B G 84  B C 109 1_555 ? ? ? ? ? ? 'G-C PAIR'              ? ? ? 
hydrog88  hydrog ? ? B C 85  N3 ? ? ? 1_555 B G 105 N1 ? ? B C 85  B G 105 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog89  hydrog ? ? B C 85  N4 ? ? ? 1_555 B G 105 O6 ? ? B C 85  B G 105 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog90  hydrog ? ? B C 85  O2 ? ? ? 1_555 B G 105 N2 ? ? B C 85  B G 105 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog91  hydrog ? ? B U 86  N3 ? ? ? 1_555 B A 104 N1 ? ? B U 86  B A 104 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog92  hydrog ? ? B U 86  O4 ? ? ? 1_555 B A 104 N6 ? ? B U 86  B A 104 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog93  hydrog ? ? B U 87  N3 ? ? ? 1_555 B G 103 O6 ? ? B U 87  B G 103 1_555 ? ? ? ? ? ? TYPE_28_PAIR            ? ? ? 
hydrog94  hydrog ? ? B U 87  O2 ? ? ? 1_555 B G 103 N1 ? ? B U 87  B G 103 1_555 ? ? ? ? ? ? TYPE_28_PAIR            ? ? ? 
hydrog95  hydrog ? ? B G 88  N1 ? ? ? 1_555 B U 102 O2 ? ? B G 88  B U 102 1_555 ? ? ? ? ? ? TYPE_28_PAIR            ? ? ? 
hydrog96  hydrog ? ? B G 88  O6 ? ? ? 1_555 B U 102 N3 ? ? B G 88  B U 102 1_555 ? ? ? ? ? ? TYPE_28_PAIR            ? ? ? 
hydrog97  hydrog ? ? B G 89  N1 ? ? ? 1_555 B C 101 N3 ? ? B G 89  B C 101 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog98  hydrog ? ? B G 89  N2 ? ? ? 1_555 B C 101 O2 ? ? B G 89  B C 101 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog99  hydrog ? ? B G 89  O6 ? ? ? 1_555 B C 101 N4 ? ? B G 89  B C 101 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog100 hydrog ? ? B G 90  N1 ? ? ? 1_555 B C 100 N3 ? ? B G 90  B C 100 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog101 hydrog ? ? B G 90  N2 ? ? ? 1_555 B C 100 O2 ? ? B G 90  B C 100 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog102 hydrog ? ? B G 90  O6 ? ? ? 1_555 B C 100 N4 ? ? B G 90  B C 100 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog103 hydrog ? ? B U 91  N3 ? ? ? 1_555 B G 99  O6 ? ? B U 91  B G 99  1_555 ? ? ? ? ? ? TYPE_28_PAIR            ? ? ? 
hydrog104 hydrog ? ? B U 91  O2 ? ? ? 1_555 B G 99  N1 ? ? B U 91  B G 99  1_555 ? ? ? ? ? ? TYPE_28_PAIR            ? ? ? 
hydrog105 hydrog ? ? B U 92  O4 ? ? ? 1_555 B A 98  N6 ? ? B U 92  B A 98  1_555 ? ? ? ? ? ? 'U-A PAIR'              ? ? ? 
hydrog106 hydrog ? ? B U 93  O4 ? ? ? 1_555 B C 97  N4 ? ? B U 93  B C 97  1_555 ? ? ? ? ? ? 'U-C MISPAIR'           ? ? ? 
hydrog107 hydrog ? ? B G 94  N1 ? ? ? 1_555 B C 145 N3 ? ? B G 94  B C 145 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog108 hydrog ? ? B G 94  N2 ? ? ? 1_555 B C 145 O2 ? ? B G 94  B C 145 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog109 hydrog ? ? B G 94  O6 ? ? ? 1_555 B C 145 N4 ? ? B G 94  B C 145 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog110 hydrog ? ? B U 95  N3 ? ? ? 1_555 B A 144 N1 ? ? B U 95  B A 144 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog111 hydrog ? ? B U 95  O4 ? ? ? 1_555 B A 144 N6 ? ? B U 95  B A 144 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog112 hydrog ? ? B C 96  N3 ? ? ? 1_555 B G 143 N1 ? ? B C 96  B G 143 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog113 hydrog ? ? B C 96  N4 ? ? ? 1_555 B G 143 O6 ? ? B C 96  B G 143 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog114 hydrog ? ? B C 96  O2 ? ? ? 1_555 B G 143 N2 ? ? B C 96  B G 143 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog115 hydrog ? ? B C 97  N3 ? ? ? 1_555 B G 142 N2 ? ? B C 97  B G 142 1_555 ? ? ? ? ? ? 'REVERSED WATSON-CRICK' ? ? ? 
hydrog116 hydrog ? ? B C 97  O2 ? ? ? 1_555 B G 142 N1 ? ? B C 97  B G 142 1_555 ? ? ? ? ? ? 'REVERSED WATSON-CRICK' ? ? ? 
hydrog117 hydrog ? ? B C 107 O2 ? ? ? 1_555 B C 109 N4 ? ? B C 107 B C 109 1_555 ? ? ? ? ? ? 'C-C MISPAIR'           ? ? ? 
hydrog118 hydrog ? ? B G 113 N1 ? ? ? 1_555 B C 124 N3 ? ? B G 113 B C 124 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog119 hydrog ? ? B G 113 N2 ? ? ? 1_555 B C 124 O2 ? ? B G 113 B C 124 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog120 hydrog ? ? B G 113 O6 ? ? ? 1_555 B C 124 N4 ? ? B G 113 B C 124 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog121 hydrog ? ? B C 114 N3 ? ? ? 1_555 B G 123 N1 ? ? B C 114 B G 123 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog122 hydrog ? ? B C 114 N4 ? ? ? 1_555 B G 123 O6 ? ? B C 114 B G 123 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog123 hydrog ? ? B C 114 O2 ? ? ? 1_555 B G 123 N2 ? ? B C 114 B G 123 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog124 hydrog ? ? B C 115 N3 ? ? ? 1_555 B G 122 N1 ? ? B C 115 B G 122 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog125 hydrog ? ? B C 115 N4 ? ? ? 1_555 B G 122 O6 ? ? B C 115 B G 122 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog126 hydrog ? ? B C 115 O2 ? ? ? 1_555 B G 122 N2 ? ? B C 115 B G 122 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog127 hydrog ? ? B A 116 N1 ? ? ? 1_555 B U 121 N3 ? ? B A 116 B U 121 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog128 hydrog ? ? B A 116 N6 ? ? ? 1_555 B U 121 O4 ? ? B A 116 B U 121 1_555 ? ? ? ? ? ? WATSON-CRICK            ? ? ? 
hydrog129 hydrog ? ? B G 117 N2 ? ? ? 1_555 B A 120 N7 ? ? B G 117 B A 120 1_555 ? ? ? ? ? ? 'G-A MISPAIR'           ? ? ? 
# 
_struct_conn_type.id          hydrog 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 3 ? 
AA2 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA2 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 SER A 819 ? LYS A 821 ? SER A 560 LYS A 562 
AA1 2 ILE A 824 ? MET A 830 ? ILE A 565 MET A 571 
AA1 3 SER A 886 ? SER A 890 ? SER A 627 SER A 631 
AA2 1 MET A 899 ? ILE A 902 ? MET A 640 ILE A 643 
AA2 2 ASN A 905 ? LYS A 908 ? ASN A 646 LYS A 649 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N SER A 819 ? N SER A 560 O THR A 826 ? O THR A 567 
AA1 2 3 N PHE A 829 ? N PHE A 570 O LEU A 887 ? O LEU A 628 
AA2 1 2 N ILE A 900 ? N ILE A 641 O PHE A 907 ? O PHE A 648 
# 
_pdbx_entry_details.entry_id                   8W2S 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_ligand_of_interest     ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1 1 CA    A LEU 224 ? ? CB    A LEU 224 ? ? CG    A LEU 224 ? ? 129.73 115.30 14.43 2.30 N 
2 1 "C3'" B U   92  ? ? "O3'" B U   92  ? ? P     B U   93  ? ? 127.22 119.70 7.52  1.20 Y 
3 1 N9    B G   142 ? ? "C1'" B G   142 ? ? "C2'" B G   142 ? ? 124.83 114.00 10.83 1.30 N 
4 1 "O4'" B G   142 ? ? "C1'" B G   142 ? ? N9    B G   142 ? ? 117.21 108.50 8.71  0.70 N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 TYR A 169 ? ? -92.73 -60.03  
2 1 LYS A 563 ? ? 38.68  40.66   
3 1 ASN A 644 ? ? 52.78  -131.28 
4 1 HIS A 653 ? ? 58.22  -129.17 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8W2S 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    8W2S 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.4 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               101411 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.9 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 Cas9d:sgRNA 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       '1, 2' 
# 
_em_imaging.entry_id                        8W2S 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             1500 
_em_imaging.nominal_defocus_max             2500 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              8W2S 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                8W2S 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A MET 1   ? A MET 1   
2   1 Y 1 A GLU 2   ? A GLU 2   
3   1 Y 1 A ARG 3   ? A ARG 3   
4   1 Y 1 A GLU 4   ? A GLU 4   
5   1 Y 1 A LEU 5   ? A LEU 5   
6   1 Y 1 A VAL 6   ? A VAL 6   
7   1 Y 1 A LEU 7   ? A LEU 7   
8   1 Y 1 A GLY 8   ? A GLY 8   
9   1 Y 1 A ILE 9   ? A ILE 9   
10  1 Y 1 A ASP 10  ? A ASP 10  
11  1 Y 1 A TYR 11  ? A TYR 11  
12  1 Y 1 A GLY 12  ? A GLY 12  
13  1 Y 1 A GLY 13  ? A GLY 13  
14  1 Y 1 A LYS 14  ? A LYS 14  
15  1 Y 1 A TYR 15  ? A TYR 15  
16  1 Y 1 A THR 16  ? A THR 16  
17  1 Y 1 A GLY 17  ? A GLY 17  
18  1 Y 1 A LEU 18  ? A LEU 18  
19  1 Y 1 A ALA 19  ? A ALA 19  
20  1 Y 1 A VAL 20  ? A VAL 20  
21  1 Y 1 A VAL 21  ? A VAL 21  
22  1 Y 1 A ASP 22  ? A ASP 22  
23  1 Y 1 A ARG 23  ? A ARG 23  
24  1 Y 1 A ARG 24  ? A ARG 24  
25  1 Y 1 A HIS 25  ? A HIS 25  
26  1 Y 1 A ASN 26  ? A ASN 26  
27  1 Y 1 A GLN 27  ? A GLN 27  
28  1 Y 1 A VAL 28  ? A VAL 28  
29  1 Y 1 A LEU 29  ? A LEU 29  
30  1 Y 1 A TYR 30  ? A TYR 30  
31  1 Y 1 A ALA 31  ? A ALA 31  
32  1 Y 1 A ASN 32  ? A ASN 32  
33  1 Y 1 A ARG 33  ? A ARG 33  
34  1 Y 1 A LEU 34  ? A LEU 34  
35  1 Y 1 A LYS 35  ? A LYS 35  
36  1 Y 1 A MET 36  ? A MET 36  
37  1 Y 1 A ARG 37  ? A ARG 37  
38  1 Y 1 A ASP 38  ? A ASP 38  
39  1 Y 1 A ASP 39  ? A ASP 39  
40  1 Y 1 A VAL 40  ? A VAL 40  
41  1 Y 1 A ALA 41  ? A ALA 41  
42  1 Y 1 A GLY 42  ? A GLY 42  
43  1 Y 1 A CYS 187 ? A CYS 187 
44  1 Y 1 A GLY 188 ? A GLY 188 
45  1 Y 1 A VAL 189 ? A VAL 189 
46  1 Y 1 A ASN 190 ? A ASN 190 
47  1 Y 1 A THR 191 ? A THR 191 
48  1 Y 1 A PRO 192 ? A PRO 192 
49  1 Y 1 A LEU 193 ? A LEU 193 
50  1 Y 1 A ARG 194 ? A ARG 194 
51  1 Y 1 A GLU 269 A A GLU 270 
52  1 Y 1 A HIS 269 B A HIS 271 
53  1 Y 1 A THR 269 C A THR 272 
54  1 Y 1 A GLU 269 D A GLU 273 
55  1 Y 1 A HIS 269 E A HIS 274 
56  1 Y 1 A SER 269 F A SER 275 
57  1 Y 1 A LYS 269 G A LYS 276 
58  1 Y 1 A GLU 269 H A GLU 277 
59  1 Y 1 A GLU 269 I A GLU 278 
60  1 Y 1 A ARG 269 J A ARG 279 
61  1 Y 1 A LYS 269 K A LYS 280 
62  1 Y 1 A VAL 269 L A VAL 281 
63  1 Y 1 A PHE 269 M A PHE 282 
64  1 Y 1 A ARG 269 N A ARG 283 
65  1 Y 1 A LEU 269 O A LEU 284 
66  1 Y 1 A ALA 269 P A ALA 285 
67  1 Y 1 A PRO 269 Q A PRO 286 
68  1 Y 1 A SER 269 R A SER 287 
69  1 Y 1 A LEU 269 S A LEU 288 
70  1 Y 1 A LYS 269 T A LYS 289 
71  1 Y 1 A THR 269 U A THR 290 
72  1 Y 1 A LYS 269 V A LYS 291 
73  1 Y 1 A ILE 269 W A ILE 292 
74  1 Y 1 A GLU 269 X A GLU 293 
75  1 Y 1 A ASN 269 Y A ASN 294 
76  1 Y 1 A VAL 269 Z A VAL 295 
77  1 Y 1 A LEU 270 A A LEU 296 
78  1 Y 1 A ALA 270 B A ALA 297 
79  1 Y 1 A VAL 270 C A VAL 298 
80  1 Y 1 A ILE 270 D A ILE 299 
81  1 Y 1 A LYS 270 E A LYS 300 
82  1 Y 1 A ASP 270 F A ASP 301 
83  1 Y 1 A GLU 270 G A GLU 302 
84  1 Y 1 A ILE 270 H A ILE 303 
85  1 Y 1 A LEU 270 I A LEU 304 
86  1 Y 1 A PRO 270 J A PRO 305 
87  1 Y 1 A LYS 270 K A LYS 306 
88  1 Y 1 A PHE 270 L A PHE 307 
89  1 Y 1 A THR 270 M A THR 308 
90  1 Y 1 A VAL 270 N A VAL 309 
91  1 Y 1 A ASN 270 O A ASN 310 
92  1 Y 1 A LYS 270 P A LYS 311 
93  1 Y 1 A VAL 270 Q A VAL 312 
94  1 Y 1 A VAL 270 R A VAL 313 
95  1 Y 1 A MET 270 S A MET 314 
96  1 Y 1 A GLU 270 T A GLU 315 
97  1 Y 1 A SER 270 U A SER 316 
98  1 Y 1 A ASN 270 V A ASN 317 
99  1 Y 1 A ASN 270 W A ASN 318 
100 1 Y 1 A PHE 270 X A PHE 319 
101 1 Y 1 A ASP 270 Y A ASP 320 
102 1 Y 1 A ILE 270 Z A ILE 321 
103 1 Y 1 A ALA 271 A A ALA 322 
104 1 Y 1 A ALA 271 B A ALA 323 
105 1 Y 1 A LYS 271 C A LYS 324 
106 1 Y 1 A THR 271 D A THR 325 
107 1 Y 1 A GLN 271 E A GLN 326 
108 1 Y 1 A GLY 271 F A GLY 327 
109 1 Y 1 A LYS 271 G A LYS 328 
110 1 Y 1 A LYS 271 H A LYS 329 
111 1 Y 1 A ARG 271 I A ARG 330 
112 1 Y 1 A LEU 271 J A LEU 331 
113 1 Y 1 A ALA 271 K A ALA 332 
114 1 Y 1 A LYS 271 L A LYS 333 
115 1 Y 1 A GLU 271 M A GLU 334 
116 1 Y 1 A GLU 271 N A GLU 335 
117 1 Y 1 A TYR 271 O A TYR 336 
118 1 Y 1 A GLY 271 P A GLY 337 
119 1 Y 1 A LYS 271 Q A LYS 338 
120 1 Y 1 A GLY 271 R A GLY 339 
121 1 Y 1 A PRO 271 S A PRO 340 
122 1 Y 1 A ARG 271 T A ARG 341 
123 1 Y 1 A GLU 271 U A GLU 342 
124 1 Y 1 A GLY 271 V A GLY 343 
125 1 Y 1 A LYS 271 W A LYS 344 
126 1 Y 1 A GLU 271 X A GLU 345 
127 1 Y 1 A THR 271 Y A THR 346 
128 1 Y 1 A ARG 271 Z A ARG 347 
129 1 Y 1 A LYS 272 A A LYS 348 
130 1 Y 1 A GLU 272 B A GLU 349 
131 1 Y 1 A ALA 272 C A ALA 350 
132 1 Y 1 A LEU 272 D A LEU 351 
133 1 Y 1 A LEU 272 E A LEU 352 
134 1 Y 1 A ARG 272 F A ARG 353 
135 1 Y 1 A GLU 272 G A GLU 354 
136 1 Y 1 A THR 272 H A THR 355 
137 1 Y 1 A ASP 272 I A ASP 356 
138 1 Y 1 A GLY 272 J A GLY 357 
139 1 Y 1 A ARG 272 K A ARG 358 
140 1 Y 1 A CYS 272 L A CYS 359 
141 1 Y 1 A ILE 272 M A ILE 360 
142 1 Y 1 A TYR 272 N A TYR 361 
143 1 Y 1 A CYS 272 O A CYS 362 
144 1 Y 1 A GLY 272 P A GLY 363 
145 1 Y 1 A LYS 272 Q A LYS 364 
146 1 Y 1 A SER 272 R A SER 365 
147 1 Y 1 A ILE 272 S A ILE 366 
148 1 Y 1 A ASP 272 T A ASP 367 
149 1 Y 1 A ILE 272 U A ILE 368 
150 1 Y 1 A SER 272 V A SER 369 
151 1 Y 1 A ASN 272 W A ASN 370 
152 1 Y 1 A ALA 272 X A ALA 371 
153 1 Y 1 A HIS 272 Y A HIS 372 
154 1 Y 1 A ASP 272 Z A ASP 373 
155 1 Y 1 A ASP 273 A A ASP 374 
156 1 Y 1 A HIS 273 B A HIS 375 
157 1 Y 1 A ILE 273 C A ILE 376 
158 1 Y 1 A PHE 273 D A PHE 377 
159 1 Y 1 A PRO 273 E A PRO 378 
160 1 Y 1 A ARG 273 F A ARG 379 
161 1 Y 1 A LYS 273 G A LYS 380 
162 1 Y 1 A ALA 273 H A ALA 381 
163 1 Y 1 A GLY 273 I A GLY 382 
164 1 Y 1 A GLY 273 J A GLY 383 
165 1 Y 1 A LEU 273 K A LEU 384 
166 1 Y 1 A ASN 273 L A ASN 385 
167 1 Y 1 A ILE 273 M A ILE 386 
168 1 Y 1 A PHE 273 N A PHE 387 
169 1 Y 1 A ALA 273 O A ALA 388 
170 1 Y 1 A ASN 273 P A ASN 389 
171 1 Y 1 A LEU 273 Q A LEU 390 
172 1 Y 1 A VAL 273 R A VAL 391 
173 1 Y 1 A ALA 273 S A ALA 392 
174 1 Y 1 A CYS 273 T A CYS 393 
175 1 Y 1 A CYS 273 U A CYS 394 
176 1 Y 1 A ALA 273 V A ALA 395 
177 1 Y 1 A VAL 273 W A VAL 396 
178 1 Y 1 A CYS 273 X A CYS 397 
179 1 Y 1 A ASN 273 Y A ASN 398 
180 1 Y 1 A GLU 273 Z A GLU 399 
181 1 Y 1 A ASN 274 A A ASN 400 
182 1 Y 1 A LYS 274 B A LYS 401 
183 1 Y 1 A LYS 274 C A LYS 402 
184 1 Y 1 A GLY 274 D A GLY 403 
185 1 Y 1 A ARG 274 E A ARG 404 
186 1 Y 1 A THR 274 F A THR 405 
187 1 Y 1 A PRO 274 G A PRO 406 
188 1 Y 1 A LEU 274 H A LEU 407 
189 1 Y 1 A GLU 274 I A GLU 408 
190 1 Y 1 A SER 274 J A SER 409 
191 1 Y 1 A GLY 274 K A GLY 410 
192 1 Y 1 A ILE 274 L A ILE 411 
193 1 Y 1 A SER 274 M A SER 412 
194 1 Y 1 A PRO 274 N A PRO 413 
195 1 Y 1 A LYS 274 O A LYS 414 
196 1 Y 1 A PRO 274 P A PRO 415 
197 1 Y 1 A GLU 274 Q A GLU 416 
198 1 Y 1 A ILE 274 R A ILE 417 
199 1 Y 1 A ILE 274 S A ILE 418 
200 1 Y 1 A ALA 274 T A ALA 419 
201 1 Y 1 A PHE 274 U A PHE 420 
202 1 Y 1 A MET 274 V A MET 421 
203 1 Y 1 A LYS 274 W A LYS 422 
204 1 Y 1 A ASN 274 X A ASN 423 
205 1 Y 1 A ASP 274 Y A ASP 424 
206 1 Y 1 A LEU 274 Z A LEU 425 
207 1 Y 1 A LYS 275 A A LYS 426 
208 1 Y 1 A LYS 275 B A LYS 427 
209 1 Y 1 A LYS 275 C A LYS 428 
210 1 Y 1 A ILE 275 D A ILE 429 
211 1 Y 1 A LEU 275 E A LEU 430 
212 1 Y 1 A GLU 275 F A GLU 431 
213 1 Y 1 A ASP 275 G A ASP 432 
214 1 Y 1 A ALA 275 H A ALA 433 
215 1 Y 1 A ARG 275 I A ARG 434 
216 1 Y 1 A ASN 275 J A ASN 435 
217 1 Y 1 A ILE 275 K A ILE 436 
218 1 Y 1 A ASN 275 L A ASN 437 
219 1 Y 1 A THR 275 M A THR 438 
220 1 Y 1 A VAL 275 N A VAL 439 
221 1 Y 1 A ASP 275 O A ASP 440 
222 1 Y 1 A PHE 275 P A PHE 441 
223 1 Y 1 A ASN 275 Q A ASN 442 
224 1 Y 1 A LYS 275 R A LYS 443 
225 1 Y 1 A TYR 275 S A TYR 444 
226 1 Y 1 A MET 275 T A MET 445 
227 1 Y 1 A SER 275 U A SER 446 
228 1 Y 1 A HIS 275 V A HIS 447 
229 1 Y 1 A ALA 275 W A ALA 448 
230 1 Y 1 A SER 275 X A SER 449 
231 1 Y 1 A ILE 275 Y A ILE 450 
232 1 Y 1 A GLY 275 Z A GLY 451 
233 1 Y 1 A TRP 276 A A TRP 452 
234 1 Y 1 A ARG 276 B A ARG 453 
235 1 Y 1 A TYR 276 C A TYR 454 
236 1 Y 1 A MET 276 D A MET 455 
237 1 Y 1 A ARG 276 E A ARG 456 
238 1 Y 1 A ASP 276 F A ASP 457 
239 1 Y 1 A ARG 276 G A ARG 458 
240 1 Y 1 A LEU 276 H A LEU 459 
241 1 Y 1 A ARG 276 I A ARG 460 
242 1 Y 1 A GLU 276 J A GLU 461 
243 1 Y 1 A SER 276 K A SER 462 
244 1 Y 1 A ALA 276 L A ALA 463 
245 1 Y 1 A GLY 276 M A GLY 464 
246 1 Y 1 A ASN 276 N A ASN 465 
247 1 Y 1 A LYS 276 O A LYS 466 
248 1 Y 1 A LYS 276 P A LYS 467 
249 1 Y 1 A LEU 276 Q A LEU 468 
250 1 Y 1 A PRO 276 R A PRO 469 
251 1 Y 1 A ILE 276 S A ILE 470 
252 1 Y 1 A GLU 276 T A GLU 471 
253 1 Y 1 A ARG 276 U A ARG 472 
254 1 Y 1 A GLN 276 V A GLN 473 
255 1 Y 1 A SER 276 W A SER 474 
256 1 Y 1 A GLY 276 X A GLY 475 
257 1 Y 1 A ILE 276 Y A ILE 476 
258 1 Y 1 A TYR 276 Z A TYR 477 
259 1 Y 1 A THR 277 A A THR 478 
260 1 Y 1 A ALA 277 B A ALA 479 
261 1 Y 1 A TYR 277 C A TYR 480 
262 1 Y 1 A PHE 277 D A PHE 481 
263 1 Y 1 A ARG 277 E A ARG 482 
264 1 Y 1 A ARG 277 F A ARG 483 
265 1 Y 1 A TRP 277 G A TRP 484 
266 1 Y 1 A TRP 277 H A TRP 485 
267 1 Y 1 A GLY 277 I A GLY 486 
268 1 Y 1 A PHE 277 J A PHE 487 
269 1 Y 1 A LYS 277 K A LYS 488 
270 1 Y 1 A LYS 277 L A LYS 489 
271 1 Y 1 A GLU 277 M A GLU 490 
272 1 Y 1 A ARG 277 N A ARG 491 
273 1 Y 1 A GLY 277 O A GLY 492 
274 1 Y 1 A ASN 277 P A ASN 493 
275 1 Y 1 A THR 277 Q A THR 494 
276 1 Y 1 A LEU 277 R A LEU 495 
277 1 Y 1 A HIS 277 S A HIS 496 
278 1 Y 1 A HIS 277 T A HIS 497 
279 1 Y 1 A ALA 277 U A ALA 498 
280 1 Y 1 A LEU 277 V A LEU 499 
281 1 Y 1 A ASP 277 W A ASP 500 
282 1 Y 1 A ALA 277 X A ALA 501 
283 1 Y 1 A VAL 277 Y A VAL 502 
284 1 Y 1 A ILE 277 Z A ILE 503 
285 1 Y 1 A LEU 278 A A LEU 504 
286 1 Y 1 A ALA 278 B A ALA 505 
287 1 Y 1 A SER 278 C A SER 506 
288 1 Y 1 A ARG 278 D A ARG 507 
289 1 Y 1 A LYS 278 E A LYS 508 
290 1 Y 1 A GLY 278 F A GLY 509 
291 1 Y 1 A TYR 278 G A TYR 510 
292 1 Y 1 A SER 278 H A SER 511 
293 1 Y 1 A ASP 278 I A ASP 512 
294 1 Y 1 A ASP 278 J A ASP 513 
295 1 Y 1 A GLY 278 K A GLY 514 
296 1 Y 1 A LEU 278 L A LEU 515 
297 1 Y 1 A VAL 278 M A VAL 516 
298 1 Y 1 A ASP 278 N A ASP 517 
299 1 Y 1 A MET 278 O A MET 518 
300 1 Y 1 A THR 278 P A THR 519 
301 1 Y 1 A LEU 278 Q A LEU 520 
302 1 Y 1 A LYS 278 R A LYS 521 
303 1 Y 1 A PRO 278 S A PRO 522 
304 1 Y 1 A LYS 278 T A LYS 523 
305 1 Y 1 A TYR 278 U A TYR 524 
306 1 Y 1 A ASN 278 V A ASN 525 
307 1 Y 1 A LYS 278 W A LYS 526 
308 1 Y 1 A GLY 278 X A GLY 527 
309 1 Y 1 A GLY 278 Y A GLY 528 
310 1 Y 1 A GLU 278 Z A GLU 529 
311 1 Y 1 A PHE 279 A A PHE 530 
312 1 Y 1 A ASP 279 B A ASP 531 
313 1 Y 1 A PRO 279 C A PRO 532 
314 1 Y 1 A GLU 279 D A GLU 533 
315 1 Y 1 A LYS 279 E A LYS 534 
316 1 Y 1 A HIS 279 F A HIS 535 
317 1 Y 1 A LEU 279 G A LEU 536 
318 1 Y 1 A PRO 279 H A PRO 537 
319 1 Y 1 A GLU 279 I A GLU 538 
320 1 Y 1 A PRO 279 J A PRO 539 
321 1 Y 1 A ILE 279 K A ILE 540 
322 1 Y 1 A GLU 279 L A GLU 541 
323 1 Y 1 A PHE 279 M A PHE 542 
324 1 Y 1 A LYS 279 N A LYS 543 
325 1 Y 1 A MET 279 O A MET 544 
326 1 Y 1 A ASP 279 P A ASP 545 
327 1 Y 1 A LYS 279 Q A LYS 546 
328 1 Y 1 A GLY 279 R A GLY 547 
329 1 Y 1 A SER 279 S A SER 548 
330 1 Y 1 A ARG 279 T A ARG 549 
331 1 Y 1 A GLY 279 U A GLY 550 
332 1 Y 1 A SER 279 V A SER 551 
333 1 Y 1 A ALA 279 W A ALA 552 
334 1 Y 1 A LEU 279 X A LEU 553 
335 1 Y 1 A HIS 279 Y A HIS 554 
336 1 Y 1 A ASP 279 Z A ASP 555 
337 1 Y 1 A ARG 280 A A ARG 556 
338 1 Y 1 A ASN 280 B A ASN 557 
339 1 Y 1 A PRO 280 C A PRO 558 
340 1 Y 1 A LEU 280 D A LEU 559 
341 1 Y 1 A SER 280 E A SER 560 
342 1 Y 1 A TYR 280 F A TYR 561 
343 1 Y 1 A LYS 280 G A LYS 562 
344 1 Y 1 A LYS 280 H A LYS 563 
345 1 Y 1 A GLY 280 I A GLY 564 
346 1 Y 1 A ILE 280 J A ILE 565 
347 1 Y 1 A ILE 280 K A ILE 566 
348 1 Y 1 A THR 280 L A THR 567 
349 1 Y 1 A ARG 280 M A ARG 568 
350 1 Y 1 A ARG 280 N A ARG 569 
351 1 Y 1 A PHE 280 O A PHE 570 
352 1 Y 1 A MET 280 P A MET 571 
353 1 Y 1 A VAL 280 Q A VAL 572 
354 1 Y 1 A THR 280 R A THR 573 
355 1 Y 1 A GLU 280 S A GLU 574 
356 1 Y 1 A ILE 280 T A ILE 575 
357 1 Y 1 A GLU 280 U A GLU 576 
358 1 Y 1 A CYS 280 V A CYS 577 
359 1 Y 1 A GLY 280 W A GLY 578 
360 1 Y 1 A LYS 280 X A LYS 579 
361 1 Y 1 A GLU 280 Y A GLU 580 
362 1 Y 1 A ASP 280 Z A ASP 581 
363 1 Y 1 A ASP 281 A A ASP 582 
364 1 Y 1 A VAL 281 B A VAL 583 
365 1 Y 1 A ILE 281 C A ILE 584 
366 1 Y 1 A SER 281 D A SER 585 
367 1 Y 1 A GLU 281 E A GLU 586 
368 1 Y 1 A THR 281 F A THR 587 
369 1 Y 1 A TYR 281 G A TYR 588 
370 1 Y 1 A ARG 281 H A ARG 589 
371 1 Y 1 A GLU 281 I A GLU 590 
372 1 Y 1 A LYS 281 J A LYS 591 
373 1 Y 1 A LEU 281 K A LEU 592 
374 1 Y 1 A LYS 281 L A LYS 593 
375 1 Y 1 A GLU 281 M A GLU 594 
376 1 Y 1 A ALA 281 N A ALA 595 
377 1 Y 1 A PHE 281 O A PHE 596 
378 1 Y 1 A LYS 281 P A LYS 597 
379 1 Y 1 A ARG 281 Q A ARG 598 
380 1 Y 1 A PHE 281 R A PHE 599 
381 1 Y 1 A ASP 281 S A ASP 600 
382 1 Y 1 A THR 281 T A THR 601 
383 1 Y 1 A LYS 281 U A LYS 602 
384 1 Y 1 A LYS 281 V A LYS 603 
385 1 Y 1 A GLY 281 W A GLY 604 
386 1 Y 1 A LYS 281 X A LYS 605 
387 1 Y 1 A CYS 281 Y A CYS 606 
388 1 Y 1 A LEU 281 Z A LEU 607 
389 1 Y 1 A THR 282 A A THR 608 
390 1 Y 1 A ASP 282 B A ASP 609 
391 1 Y 1 A LYS 282 C A LYS 610 
392 1 Y 1 A GLU 282 D A GLU 611 
393 1 Y 1 A ALA 282 E A ALA 612 
394 1 Y 1 A LYS 282 F A LYS 613 
395 1 Y 1 A GLU 282 G A GLU 614 
396 1 Y 1 A ALA 282 H A ALA 615 
397 1 Y 1 A GLY 282 I A GLY 616 
398 1 Y 1 A PHE 282 J A PHE 617 
399 1 Y 1 A CYS 282 K A CYS 618 
400 1 Y 1 A ILE 282 L A ILE 619 
401 1 Y 1 A LYS 282 M A LYS 620 
402 1 Y 1 A LYS 282 N A LYS 621 
403 1 Y 1 A ASN 282 O A ASN 622 
404 1 Y 1 A GLU 282 P A GLU 623 
405 1 Y 1 A LEU 282 Q A LEU 624 
406 1 Y 1 A VAL 282 R A VAL 625 
407 1 Y 1 A MET 282 S A MET 626 
408 1 Y 1 A SER 282 T A SER 627 
409 1 Y 1 A LEU 282 U A LEU 628 
410 1 Y 1 A LYS 282 V A LYS 629 
411 1 Y 1 A CYS 282 W A CYS 630 
412 1 Y 1 A SER 282 X A SER 631 
413 1 Y 1 A ILE 282 Y A ILE 632 
414 1 Y 1 A LYS 282 Z A LYS 633 
415 1 Y 1 A GLY 283 A A GLY 634 
416 1 Y 1 A THR 283 B A THR 635 
417 1 Y 1 A GLY 283 C A GLY 636 
418 1 Y 1 A PRO 283 D A PRO 637 
419 1 Y 1 A GLY 283 E A GLY 638 
420 1 Y 1 A GLN 283 F A GLN 639 
421 1 Y 1 A MET 283 G A MET 640 
422 1 Y 1 A ILE 283 H A ILE 641 
423 1 Y 1 A ARG 283 I A ARG 642 
424 1 Y 1 A ILE 283 J A ILE 643 
425 1 Y 1 A ASN 283 K A ASN 644 
426 1 Y 1 A ASN 283 L A ASN 645 
427 1 Y 1 A ASN 283 M A ASN 646 
428 1 Y 1 A VAL 283 N A VAL 647 
429 1 Y 1 A PHE 283 O A PHE 648 
430 1 Y 1 A LYS 283 P A LYS 649 
431 1 Y 1 A THR 283 Q A THR 650 
432 1 Y 1 A ASN 283 R A ASN 651 
433 1 Y 1 A VAL 283 S A VAL 652 
434 1 Y 1 A HIS 283 T A HIS 653 
435 1 Y 1 A ASN 283 U A ASN 654 
436 1 Y 1 A VAL 283 V A VAL 655 
437 1 Y 1 A GLY 283 W A GLY 656 
438 1 Y 1 A VAL 283 X A VAL 657 
439 1 Y 1 A ASP 283 Y A ASP 658 
440 1 Y 1 A VAL 283 Z A VAL 659 
441 1 Y 1 A TYR 284 A A TYR 660 
442 1 Y 1 A LEU 284 B A LEU 661 
443 1 Y 1 A ASP 284 C A ASP 662 
444 1 Y 1 A GLU 284 D A GLU 663 
445 1 Y 1 A LYS 284 E A LYS 664 
446 1 Y 1 A GLY 284 F A GLY 665 
447 1 Y 1 A LYS 284 G A LYS 666 
448 1 Y 1 A LYS 284 H A LYS 667 
449 1 Y 1 A LYS 284 I A LYS 668 
450 1 Y 1 A ALA 284 J A ALA 669 
451 1 Y 1 A TYR 284 K A TYR 670 
452 1 Y 1 A GLU 284 L A GLU 671 
453 1 Y 1 A ARG 284 M A ARG 672 
454 1 Y 1 A LYS 284 N A LYS 673 
455 1 Y 1 A ASN 284 O A ASN 674 
456 1 Y 1 A PRO 284 P A PRO 675 
457 1 Y 1 A ARG 284 Q A ARG 676 
458 1 Y 1 A LEU 284 R A LEU 677 
459 1 Y 1 A SER 284 S A SER 678 
460 1 Y 1 A LYS 284 T A LYS 679 
461 1 Y 1 A HIS 284 U A HIS 680 
462 1 Y 1 A PHE 284 V A PHE 681 
463 1 Y 1 A ILE 284 W A ILE 682 
464 1 Y 1 A GLU 284 X A GLU 683 
465 1 Y 1 A PRO 284 Y A PRO 684 
466 1 Y 1 A PRO 284 Z A PRO 685 
467 1 Y 1 A PRO 285 A A PRO 686 
468 1 Y 1 A GLN 285 B A GLN 687 
469 1 Y 1 A PRO 285 C A PRO 688 
470 1 Y 1 A ASN 285 D A ASN 689 
471 1 Y 1 A GLY 285 E A GLY 690 
472 1 Y 1 A ARG 285 F A ARG 691 
473 1 Y 1 A VAL 285 G A VAL 692 
474 1 Y 1 A SER 285 H A SER 693 
475 1 Y 1 A PHE 285 I A PHE 694 
476 1 Y 1 A THR 285 J A THR 695 
477 1 Y 1 A LEU 285 K A LEU 696 
478 1 Y 1 A LYS 285 L A LYS 697 
479 1 Y 1 A ARG 285 M A ARG 698 
480 1 Y 1 A ARG 285 N A ARG 699 
481 1 Y 1 A ASP 285 O A ASP 700 
482 1 Y 1 A MET 285 P A MET 701 
483 1 Y 1 A VAL 285 Q A VAL 702 
484 1 Y 1 A THR 285 R A THR 703 
485 1 Y 1 A VAL 285 S A VAL 704 
486 1 Y 1 A GLU 285 T A GLU 705 
487 1 Y 1 A GLY 285 U A GLY 706 
488 1 Y 1 A GLU 285 V A GLU 707 
489 1 Y 1 A ASP 285 W A ASP 708 
490 1 Y 1 A ALA 285 X A ALA 709 
491 1 Y 1 A ILE 285 Y A ILE 710 
492 1 Y 1 A TYR 285 Z A TYR 711 
493 1 Y 1 A ARG 286 A A ARG 712 
494 1 Y 1 A ILE 286 B A ILE 713 
495 1 Y 1 A LYS 286 C A LYS 714 
496 1 Y 1 A LYS 286 D A LYS 715 
497 1 Y 1 A LEU 286 E A LEU 716 
498 1 Y 1 A GLY 286 F A GLY 717 
499 1 Y 1 A THR 286 G A THR 718 
500 1 Y 1 A SER 286 H A SER 719 
501 1 Y 1 A PRO 286 I A PRO 720 
502 1 Y 1 A THR 286 J A THR 721 
503 1 Y 1 A ILE 286 K A ILE 722 
504 1 Y 1 A GLU 286 L A GLU 723 
505 1 Y 1 A ALA 286 M A ALA 724 
506 1 Y 1 A VAL 286 N A VAL 725 
507 1 Y 1 A VAL 286 O A VAL 726 
508 1 Y 1 A GLY 286 P A GLY 727 
509 1 Y 1 A SER 286 Q A SER 728 
510 1 Y 1 A ASP 286 R A ASP 729 
511 1 Y 1 A GLY 286 S A GLY 730 
512 1 Y 1 A LYS 286 T A LYS 731 
513 1 Y 1 A THR 286 U A THR 732 
514 1 Y 1 A ARG 286 V A ARG 733 
515 1 Y 1 A THR 286 W A THR 734 
516 1 Y 1 A VAL 286 X A VAL 735 
517 1 Y 1 A SER 286 Y A SER 736 
518 1 Y 1 A ALA 286 Z A ALA 737 
519 1 Y 1 A THR 287 A A THR 738 
520 1 Y 1 A LYS 287 B A LYS 739 
521 1 Y 1 A LEU 287 C A LEU 740 
522 1 Y 1 A THR 287 D A THR 741 
523 1 Y 1 A LYS 287 E A LYS 742 
524 1 Y 1 A ALA 287 F A ALA 743 
525 1 Y 1 A ASN 287 G A ASN 744 
526 1 Y 1 A SER 287 H A SER 745 
527 1 Y 1 A ALA 287 I A ALA 746 
528 1 Y 1 A GLU 287 J A GLU 747 
529 1 Y 1 A ILE 287 K A ILE 748 
530 1 Y 1 A GLU 287 L A GLU 749 
531 1 Y 1 A GLN 287 M A GLN 750 
532 1 Y 1 A SER 287 N A SER 751 
533 1 Y 1 A GLU 287 O A GLU 752 
534 1 Y 1 A LYS 287 P A LYS 753 
535 1 Y 1 A ASP 287 Q A ASP 754 
536 1 Y 1 A ASN 287 R A ASN 755 
537 1 Y 1 A LEU 287 S A LEU 756 
538 1 Y 1 A LYS 287 T A LYS 757 
539 1 Y 1 A ASP 287 U A ASP 758 
540 1 Y 1 A ALA 287 V A ALA 759 
541 1 Y 1 A VAL 287 W A VAL 760 
542 1 Y 1 A LEU 287 X A LEU 761 
543 1 Y 1 A ASP 287 Y A ASP 762 
544 1 Y 1 A LYS 287 Z A LYS 763 
545 1 Y 1 A ASN 288 A A ASN 764 
546 1 Y 1 A ARG 288 B A ARG 765 
547 1 Y 1 A ARG 288 C A ARG 766 
548 1 Y 1 A GLU 288 D A GLU 767 
549 1 Y 1 A GLU 288 E A GLU 768 
550 1 Y 1 A VAL 288 F A VAL 769 
551 1 Y 1 A LYS 288 G A LYS 770 
552 1 Y 1 A SER 288 H A SER 771 
553 1 Y 1 A PHE 288 I A PHE 772 
554 1 Y 1 A PHE 288 J A PHE 773 
555 1 Y 1 A ARG 288 K A ARG 774 
556 1 Y 1 A LYS 288 L A LYS 775 
557 1 Y 1 A HIS 288 M A HIS 776 
558 1 Y 1 A LYS 288 N A LYS 777 
559 1 Y 1 A THR 288 O A THR 778 
560 1 Y 1 A ASP 288 P A ASP 779 
561 1 Y 1 A GLU 288 Q A GLU 780 
562 1 Y 1 A HIS 288 R A HIS 781 
563 1 Y 1 A ILE 288 S A ILE 782 
564 1 Y 1 A ARG 288 T A ARG 783 
565 1 Y 1 A LYS 288 U A LYS 784 
566 1 Y 1 A GLN 288 V A GLN 785 
567 1 Y 1 A VAL 288 W A VAL 786 
568 1 Y 1 A TYR 288 X A TYR 787 
569 1 Y 1 A ASP 288 Y A ASP 788 
570 1 Y 1 A ILE 288 Z A ILE 789 
571 1 Y 1 A ALA 289 A A ALA 790 
572 1 Y 1 A ASP 289 B A ASP 791 
573 1 Y 1 A ASN 289 C A ASN 792 
574 1 Y 1 A LYS 289 D A LYS 793 
575 1 Y 1 A LEU 289 E A LEU 794 
576 1 Y 1 A SER 289 F A SER 795 
577 1 Y 1 A GLY 289 G A GLY 796 
578 1 Y 1 A ARG 289 H A ARG 797 
579 1 Y 1 A THR 289 I A THR 798 
580 1 Y 1 A VAL 289 J A VAL 799 
581 1 Y 1 A PHE 289 K A PHE 800 
582 1 Y 1 A CYS 289 L A CYS 801 
583 1 Y 1 A LYS 289 M A LYS 802 
584 1 Y 1 A GLU 289 N A GLU 803 
585 1 Y 1 A HIS 289 O A HIS 804 
586 1 Y 1 A ILE 289 P A ILE 805 
587 1 Y 1 A LEU 289 Q A LEU 806 
588 1 Y 1 A UNK 656 ? A UNK 915 
589 1 Y 1 A UNK 657 ? A UNK 916 
590 1 Y 1 A UNK 658 ? A UNK 917 
591 1 Y 1 A UNK 659 ? A UNK 918 
592 1 Y 1 A UNK 660 ? A UNK 919 
593 1 Y 1 A UNK 661 ? A UNK 920 
594 1 Y 1 A UNK 662 ? A UNK 921 
595 1 Y 1 A UNK 663 ? A UNK 922 
596 1 Y 1 A UNK 664 ? A UNK 923 
597 1 Y 1 A UNK 665 ? A UNK 924 
598 1 Y 1 A UNK 666 ? A UNK 925 
599 1 Y 1 A UNK 667 ? A UNK 926 
600 1 Y 1 A UNK 668 ? A UNK 927 
601 1 Y 1 A UNK 669 ? A UNK 928 
602 1 Y 1 A UNK 670 ? A UNK 929 
603 1 Y 1 A UNK 671 ? A UNK 930 
604 1 Y 1 B G   1   ? B G   1   
605 1 Y 1 B A   2   ? B A   2   
606 1 Y 1 B C   3   ? B C   3   
607 1 Y 1 B G   4   ? B G   4   
608 1 Y 1 B C   5   ? B C   5   
609 1 Y 1 B A   6   ? B A   6   
610 1 Y 1 B U   7   ? B U   7   
611 1 Y 1 B A   8   ? B A   8   
612 1 Y 1 B A   9   ? B A   9   
613 1 Y 1 B U   147 ? B U   147 
614 1 Y 1 B U   148 ? B U   148 
615 1 Y 1 B U   149 ? B U   149 
616 1 Y 1 B A   150 ? B A   150 
617 1 Y 1 B A   151 ? B A   151 
618 1 Y 1 B U   152 ? B U   152 
619 1 Y 1 B U   153 ? B U   153 
620 1 Y 1 B U   154 ? B U   154 
621 1 Y 1 B U   155 ? B U   155 
622 1 Y 1 B U   156 ? B U   156 
623 1 Y 1 B U   157 ? B U   157 
624 1 Y 1 B U   158 ? B U   158 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
A   OP3    O N N 1   
A   P      P N N 2   
A   OP1    O N N 3   
A   OP2    O N N 4   
A   "O5'"  O N N 5   
A   "C5'"  C N N 6   
A   "C4'"  C N R 7   
A   "O4'"  O N N 8   
A   "C3'"  C N S 9   
A   "O3'"  O N N 10  
A   "C2'"  C N R 11  
A   "O2'"  O N N 12  
A   "C1'"  C N R 13  
A   N9     N Y N 14  
A   C8     C Y N 15  
A   N7     N Y N 16  
A   C5     C Y N 17  
A   C6     C Y N 18  
A   N6     N N N 19  
A   N1     N Y N 20  
A   C2     C Y N 21  
A   N3     N Y N 22  
A   C4     C Y N 23  
A   HOP3   H N N 24  
A   HOP2   H N N 25  
A   "H5'"  H N N 26  
A   "H5''" H N N 27  
A   "H4'"  H N N 28  
A   "H3'"  H N N 29  
A   "HO3'" H N N 30  
A   "H2'"  H N N 31  
A   "HO2'" H N N 32  
A   "H1'"  H N N 33  
A   H8     H N N 34  
A   H61    H N N 35  
A   H62    H N N 36  
A   H2     H N N 37  
ALA N      N N N 38  
ALA CA     C N S 39  
ALA C      C N N 40  
ALA O      O N N 41  
ALA CB     C N N 42  
ALA OXT    O N N 43  
ALA H      H N N 44  
ALA H2     H N N 45  
ALA HA     H N N 46  
ALA HB1    H N N 47  
ALA HB2    H N N 48  
ALA HB3    H N N 49  
ALA HXT    H N N 50  
ARG N      N N N 51  
ARG CA     C N S 52  
ARG C      C N N 53  
ARG O      O N N 54  
ARG CB     C N N 55  
ARG CG     C N N 56  
ARG CD     C N N 57  
ARG NE     N N N 58  
ARG CZ     C N N 59  
ARG NH1    N N N 60  
ARG NH2    N N N 61  
ARG OXT    O N N 62  
ARG H      H N N 63  
ARG H2     H N N 64  
ARG HA     H N N 65  
ARG HB2    H N N 66  
ARG HB3    H N N 67  
ARG HG2    H N N 68  
ARG HG3    H N N 69  
ARG HD2    H N N 70  
ARG HD3    H N N 71  
ARG HE     H N N 72  
ARG HH11   H N N 73  
ARG HH12   H N N 74  
ARG HH21   H N N 75  
ARG HH22   H N N 76  
ARG HXT    H N N 77  
ASN N      N N N 78  
ASN CA     C N S 79  
ASN C      C N N 80  
ASN O      O N N 81  
ASN CB     C N N 82  
ASN CG     C N N 83  
ASN OD1    O N N 84  
ASN ND2    N N N 85  
ASN OXT    O N N 86  
ASN H      H N N 87  
ASN H2     H N N 88  
ASN HA     H N N 89  
ASN HB2    H N N 90  
ASN HB3    H N N 91  
ASN HD21   H N N 92  
ASN HD22   H N N 93  
ASN HXT    H N N 94  
ASP N      N N N 95  
ASP CA     C N S 96  
ASP C      C N N 97  
ASP O      O N N 98  
ASP CB     C N N 99  
ASP CG     C N N 100 
ASP OD1    O N N 101 
ASP OD2    O N N 102 
ASP OXT    O N N 103 
ASP H      H N N 104 
ASP H2     H N N 105 
ASP HA     H N N 106 
ASP HB2    H N N 107 
ASP HB3    H N N 108 
ASP HD2    H N N 109 
ASP HXT    H N N 110 
C   OP3    O N N 111 
C   P      P N N 112 
C   OP1    O N N 113 
C   OP2    O N N 114 
C   "O5'"  O N N 115 
C   "C5'"  C N N 116 
C   "C4'"  C N R 117 
C   "O4'"  O N N 118 
C   "C3'"  C N S 119 
C   "O3'"  O N N 120 
C   "C2'"  C N R 121 
C   "O2'"  O N N 122 
C   "C1'"  C N R 123 
C   N1     N N N 124 
C   C2     C N N 125 
C   O2     O N N 126 
C   N3     N N N 127 
C   C4     C N N 128 
C   N4     N N N 129 
C   C5     C N N 130 
C   C6     C N N 131 
C   HOP3   H N N 132 
C   HOP2   H N N 133 
C   "H5'"  H N N 134 
C   "H5''" H N N 135 
C   "H4'"  H N N 136 
C   "H3'"  H N N 137 
C   "HO3'" H N N 138 
C   "H2'"  H N N 139 
C   "HO2'" H N N 140 
C   "H1'"  H N N 141 
C   H41    H N N 142 
C   H42    H N N 143 
C   H5     H N N 144 
C   H6     H N N 145 
CYS N      N N N 146 
CYS CA     C N R 147 
CYS C      C N N 148 
CYS O      O N N 149 
CYS CB     C N N 150 
CYS SG     S N N 151 
CYS OXT    O N N 152 
CYS H      H N N 153 
CYS H2     H N N 154 
CYS HA     H N N 155 
CYS HB2    H N N 156 
CYS HB3    H N N 157 
CYS HG     H N N 158 
CYS HXT    H N N 159 
G   OP3    O N N 160 
G   P      P N N 161 
G   OP1    O N N 162 
G   OP2    O N N 163 
G   "O5'"  O N N 164 
G   "C5'"  C N N 165 
G   "C4'"  C N R 166 
G   "O4'"  O N N 167 
G   "C3'"  C N S 168 
G   "O3'"  O N N 169 
G   "C2'"  C N R 170 
G   "O2'"  O N N 171 
G   "C1'"  C N R 172 
G   N9     N Y N 173 
G   C8     C Y N 174 
G   N7     N Y N 175 
G   C5     C Y N 176 
G   C6     C N N 177 
G   O6     O N N 178 
G   N1     N N N 179 
G   C2     C N N 180 
G   N2     N N N 181 
G   N3     N N N 182 
G   C4     C Y N 183 
G   HOP3   H N N 184 
G   HOP2   H N N 185 
G   "H5'"  H N N 186 
G   "H5''" H N N 187 
G   "H4'"  H N N 188 
G   "H3'"  H N N 189 
G   "HO3'" H N N 190 
G   "H2'"  H N N 191 
G   "HO2'" H N N 192 
G   "H1'"  H N N 193 
G   H8     H N N 194 
G   H1     H N N 195 
G   H21    H N N 196 
G   H22    H N N 197 
GLN N      N N N 198 
GLN CA     C N S 199 
GLN C      C N N 200 
GLN O      O N N 201 
GLN CB     C N N 202 
GLN CG     C N N 203 
GLN CD     C N N 204 
GLN OE1    O N N 205 
GLN NE2    N N N 206 
GLN OXT    O N N 207 
GLN H      H N N 208 
GLN H2     H N N 209 
GLN HA     H N N 210 
GLN HB2    H N N 211 
GLN HB3    H N N 212 
GLN HG2    H N N 213 
GLN HG3    H N N 214 
GLN HE21   H N N 215 
GLN HE22   H N N 216 
GLN HXT    H N N 217 
GLU N      N N N 218 
GLU CA     C N S 219 
GLU C      C N N 220 
GLU O      O N N 221 
GLU CB     C N N 222 
GLU CG     C N N 223 
GLU CD     C N N 224 
GLU OE1    O N N 225 
GLU OE2    O N N 226 
GLU OXT    O N N 227 
GLU H      H N N 228 
GLU H2     H N N 229 
GLU HA     H N N 230 
GLU HB2    H N N 231 
GLU HB3    H N N 232 
GLU HG2    H N N 233 
GLU HG3    H N N 234 
GLU HE2    H N N 235 
GLU HXT    H N N 236 
GLY N      N N N 237 
GLY CA     C N N 238 
GLY C      C N N 239 
GLY O      O N N 240 
GLY OXT    O N N 241 
GLY H      H N N 242 
GLY H2     H N N 243 
GLY HA2    H N N 244 
GLY HA3    H N N 245 
GLY HXT    H N N 246 
HIS N      N N N 247 
HIS CA     C N S 248 
HIS C      C N N 249 
HIS O      O N N 250 
HIS CB     C N N 251 
HIS CG     C Y N 252 
HIS ND1    N Y N 253 
HIS CD2    C Y N 254 
HIS CE1    C Y N 255 
HIS NE2    N Y N 256 
HIS OXT    O N N 257 
HIS H      H N N 258 
HIS H2     H N N 259 
HIS HA     H N N 260 
HIS HB2    H N N 261 
HIS HB3    H N N 262 
HIS HD1    H N N 263 
HIS HD2    H N N 264 
HIS HE1    H N N 265 
HIS HE2    H N N 266 
HIS HXT    H N N 267 
ILE N      N N N 268 
ILE CA     C N S 269 
ILE C      C N N 270 
ILE O      O N N 271 
ILE CB     C N S 272 
ILE CG1    C N N 273 
ILE CG2    C N N 274 
ILE CD1    C N N 275 
ILE OXT    O N N 276 
ILE H      H N N 277 
ILE H2     H N N 278 
ILE HA     H N N 279 
ILE HB     H N N 280 
ILE HG12   H N N 281 
ILE HG13   H N N 282 
ILE HG21   H N N 283 
ILE HG22   H N N 284 
ILE HG23   H N N 285 
ILE HD11   H N N 286 
ILE HD12   H N N 287 
ILE HD13   H N N 288 
ILE HXT    H N N 289 
LEU N      N N N 290 
LEU CA     C N S 291 
LEU C      C N N 292 
LEU O      O N N 293 
LEU CB     C N N 294 
LEU CG     C N N 295 
LEU CD1    C N N 296 
LEU CD2    C N N 297 
LEU OXT    O N N 298 
LEU H      H N N 299 
LEU H2     H N N 300 
LEU HA     H N N 301 
LEU HB2    H N N 302 
LEU HB3    H N N 303 
LEU HG     H N N 304 
LEU HD11   H N N 305 
LEU HD12   H N N 306 
LEU HD13   H N N 307 
LEU HD21   H N N 308 
LEU HD22   H N N 309 
LEU HD23   H N N 310 
LEU HXT    H N N 311 
LYS N      N N N 312 
LYS CA     C N S 313 
LYS C      C N N 314 
LYS O      O N N 315 
LYS CB     C N N 316 
LYS CG     C N N 317 
LYS CD     C N N 318 
LYS CE     C N N 319 
LYS NZ     N N N 320 
LYS OXT    O N N 321 
LYS H      H N N 322 
LYS H2     H N N 323 
LYS HA     H N N 324 
LYS HB2    H N N 325 
LYS HB3    H N N 326 
LYS HG2    H N N 327 
LYS HG3    H N N 328 
LYS HD2    H N N 329 
LYS HD3    H N N 330 
LYS HE2    H N N 331 
LYS HE3    H N N 332 
LYS HZ1    H N N 333 
LYS HZ2    H N N 334 
LYS HZ3    H N N 335 
LYS HXT    H N N 336 
MET N      N N N 337 
MET CA     C N S 338 
MET C      C N N 339 
MET O      O N N 340 
MET CB     C N N 341 
MET CG     C N N 342 
MET SD     S N N 343 
MET CE     C N N 344 
MET OXT    O N N 345 
MET H      H N N 346 
MET H2     H N N 347 
MET HA     H N N 348 
MET HB2    H N N 349 
MET HB3    H N N 350 
MET HG2    H N N 351 
MET HG3    H N N 352 
MET HE1    H N N 353 
MET HE2    H N N 354 
MET HE3    H N N 355 
MET HXT    H N N 356 
PHE N      N N N 357 
PHE CA     C N S 358 
PHE C      C N N 359 
PHE O      O N N 360 
PHE CB     C N N 361 
PHE CG     C Y N 362 
PHE CD1    C Y N 363 
PHE CD2    C Y N 364 
PHE CE1    C Y N 365 
PHE CE2    C Y N 366 
PHE CZ     C Y N 367 
PHE OXT    O N N 368 
PHE H      H N N 369 
PHE H2     H N N 370 
PHE HA     H N N 371 
PHE HB2    H N N 372 
PHE HB3    H N N 373 
PHE HD1    H N N 374 
PHE HD2    H N N 375 
PHE HE1    H N N 376 
PHE HE2    H N N 377 
PHE HZ     H N N 378 
PHE HXT    H N N 379 
PRO N      N N N 380 
PRO CA     C N S 381 
PRO C      C N N 382 
PRO O      O N N 383 
PRO CB     C N N 384 
PRO CG     C N N 385 
PRO CD     C N N 386 
PRO OXT    O N N 387 
PRO H      H N N 388 
PRO HA     H N N 389 
PRO HB2    H N N 390 
PRO HB3    H N N 391 
PRO HG2    H N N 392 
PRO HG3    H N N 393 
PRO HD2    H N N 394 
PRO HD3    H N N 395 
PRO HXT    H N N 396 
SER N      N N N 397 
SER CA     C N S 398 
SER C      C N N 399 
SER O      O N N 400 
SER CB     C N N 401 
SER OG     O N N 402 
SER OXT    O N N 403 
SER H      H N N 404 
SER H2     H N N 405 
SER HA     H N N 406 
SER HB2    H N N 407 
SER HB3    H N N 408 
SER HG     H N N 409 
SER HXT    H N N 410 
THR N      N N N 411 
THR CA     C N S 412 
THR C      C N N 413 
THR O      O N N 414 
THR CB     C N R 415 
THR OG1    O N N 416 
THR CG2    C N N 417 
THR OXT    O N N 418 
THR H      H N N 419 
THR H2     H N N 420 
THR HA     H N N 421 
THR HB     H N N 422 
THR HG1    H N N 423 
THR HG21   H N N 424 
THR HG22   H N N 425 
THR HG23   H N N 426 
THR HXT    H N N 427 
TRP N      N N N 428 
TRP CA     C N S 429 
TRP C      C N N 430 
TRP O      O N N 431 
TRP CB     C N N 432 
TRP CG     C Y N 433 
TRP CD1    C Y N 434 
TRP CD2    C Y N 435 
TRP NE1    N Y N 436 
TRP CE2    C Y N 437 
TRP CE3    C Y N 438 
TRP CZ2    C Y N 439 
TRP CZ3    C Y N 440 
TRP CH2    C Y N 441 
TRP OXT    O N N 442 
TRP H      H N N 443 
TRP H2     H N N 444 
TRP HA     H N N 445 
TRP HB2    H N N 446 
TRP HB3    H N N 447 
TRP HD1    H N N 448 
TRP HE1    H N N 449 
TRP HE3    H N N 450 
TRP HZ2    H N N 451 
TRP HZ3    H N N 452 
TRP HH2    H N N 453 
TRP HXT    H N N 454 
TYR N      N N N 455 
TYR CA     C N S 456 
TYR C      C N N 457 
TYR O      O N N 458 
TYR CB     C N N 459 
TYR CG     C Y N 460 
TYR CD1    C Y N 461 
TYR CD2    C Y N 462 
TYR CE1    C Y N 463 
TYR CE2    C Y N 464 
TYR CZ     C Y N 465 
TYR OH     O N N 466 
TYR OXT    O N N 467 
TYR H      H N N 468 
TYR H2     H N N 469 
TYR HA     H N N 470 
TYR HB2    H N N 471 
TYR HB3    H N N 472 
TYR HD1    H N N 473 
TYR HD2    H N N 474 
TYR HE1    H N N 475 
TYR HE2    H N N 476 
TYR HH     H N N 477 
TYR HXT    H N N 478 
U   OP3    O N N 479 
U   P      P N N 480 
U   OP1    O N N 481 
U   OP2    O N N 482 
U   "O5'"  O N N 483 
U   "C5'"  C N N 484 
U   "C4'"  C N R 485 
U   "O4'"  O N N 486 
U   "C3'"  C N S 487 
U   "O3'"  O N N 488 
U   "C2'"  C N R 489 
U   "O2'"  O N N 490 
U   "C1'"  C N R 491 
U   N1     N N N 492 
U   C2     C N N 493 
U   O2     O N N 494 
U   N3     N N N 495 
U   C4     C N N 496 
U   O4     O N N 497 
U   C5     C N N 498 
U   C6     C N N 499 
U   HOP3   H N N 500 
U   HOP2   H N N 501 
U   "H5'"  H N N 502 
U   "H5''" H N N 503 
U   "H4'"  H N N 504 
U   "H3'"  H N N 505 
U   "HO3'" H N N 506 
U   "H2'"  H N N 507 
U   "HO2'" H N N 508 
U   "H1'"  H N N 509 
U   H3     H N N 510 
U   H5     H N N 511 
U   H6     H N N 512 
VAL N      N N N 513 
VAL CA     C N S 514 
VAL C      C N N 515 
VAL O      O N N 516 
VAL CB     C N N 517 
VAL CG1    C N N 518 
VAL CG2    C N N 519 
VAL OXT    O N N 520 
VAL H      H N N 521 
VAL H2     H N N 522 
VAL HA     H N N 523 
VAL HB     H N N 524 
VAL HG11   H N N 525 
VAL HG12   H N N 526 
VAL HG13   H N N 527 
VAL HG21   H N N 528 
VAL HG22   H N N 529 
VAL HG23   H N N 530 
VAL HXT    H N N 531 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
A   OP3   P      sing N N 1   
A   OP3   HOP3   sing N N 2   
A   P     OP1    doub N N 3   
A   P     OP2    sing N N 4   
A   P     "O5'"  sing N N 5   
A   OP2   HOP2   sing N N 6   
A   "O5'" "C5'"  sing N N 7   
A   "C5'" "C4'"  sing N N 8   
A   "C5'" "H5'"  sing N N 9   
A   "C5'" "H5''" sing N N 10  
A   "C4'" "O4'"  sing N N 11  
A   "C4'" "C3'"  sing N N 12  
A   "C4'" "H4'"  sing N N 13  
A   "O4'" "C1'"  sing N N 14  
A   "C3'" "O3'"  sing N N 15  
A   "C3'" "C2'"  sing N N 16  
A   "C3'" "H3'"  sing N N 17  
A   "O3'" "HO3'" sing N N 18  
A   "C2'" "O2'"  sing N N 19  
A   "C2'" "C1'"  sing N N 20  
A   "C2'" "H2'"  sing N N 21  
A   "O2'" "HO2'" sing N N 22  
A   "C1'" N9     sing N N 23  
A   "C1'" "H1'"  sing N N 24  
A   N9    C8     sing Y N 25  
A   N9    C4     sing Y N 26  
A   C8    N7     doub Y N 27  
A   C8    H8     sing N N 28  
A   N7    C5     sing Y N 29  
A   C5    C6     sing Y N 30  
A   C5    C4     doub Y N 31  
A   C6    N6     sing N N 32  
A   C6    N1     doub Y N 33  
A   N6    H61    sing N N 34  
A   N6    H62    sing N N 35  
A   N1    C2     sing Y N 36  
A   C2    N3     doub Y N 37  
A   C2    H2     sing N N 38  
A   N3    C4     sing Y N 39  
ALA N     CA     sing N N 40  
ALA N     H      sing N N 41  
ALA N     H2     sing N N 42  
ALA CA    C      sing N N 43  
ALA CA    CB     sing N N 44  
ALA CA    HA     sing N N 45  
ALA C     O      doub N N 46  
ALA C     OXT    sing N N 47  
ALA CB    HB1    sing N N 48  
ALA CB    HB2    sing N N 49  
ALA CB    HB3    sing N N 50  
ALA OXT   HXT    sing N N 51  
ARG N     CA     sing N N 52  
ARG N     H      sing N N 53  
ARG N     H2     sing N N 54  
ARG CA    C      sing N N 55  
ARG CA    CB     sing N N 56  
ARG CA    HA     sing N N 57  
ARG C     O      doub N N 58  
ARG C     OXT    sing N N 59  
ARG CB    CG     sing N N 60  
ARG CB    HB2    sing N N 61  
ARG CB    HB3    sing N N 62  
ARG CG    CD     sing N N 63  
ARG CG    HG2    sing N N 64  
ARG CG    HG3    sing N N 65  
ARG CD    NE     sing N N 66  
ARG CD    HD2    sing N N 67  
ARG CD    HD3    sing N N 68  
ARG NE    CZ     sing N N 69  
ARG NE    HE     sing N N 70  
ARG CZ    NH1    sing N N 71  
ARG CZ    NH2    doub N N 72  
ARG NH1   HH11   sing N N 73  
ARG NH1   HH12   sing N N 74  
ARG NH2   HH21   sing N N 75  
ARG NH2   HH22   sing N N 76  
ARG OXT   HXT    sing N N 77  
ASN N     CA     sing N N 78  
ASN N     H      sing N N 79  
ASN N     H2     sing N N 80  
ASN CA    C      sing N N 81  
ASN CA    CB     sing N N 82  
ASN CA    HA     sing N N 83  
ASN C     O      doub N N 84  
ASN C     OXT    sing N N 85  
ASN CB    CG     sing N N 86  
ASN CB    HB2    sing N N 87  
ASN CB    HB3    sing N N 88  
ASN CG    OD1    doub N N 89  
ASN CG    ND2    sing N N 90  
ASN ND2   HD21   sing N N 91  
ASN ND2   HD22   sing N N 92  
ASN OXT   HXT    sing N N 93  
ASP N     CA     sing N N 94  
ASP N     H      sing N N 95  
ASP N     H2     sing N N 96  
ASP CA    C      sing N N 97  
ASP CA    CB     sing N N 98  
ASP CA    HA     sing N N 99  
ASP C     O      doub N N 100 
ASP C     OXT    sing N N 101 
ASP CB    CG     sing N N 102 
ASP CB    HB2    sing N N 103 
ASP CB    HB3    sing N N 104 
ASP CG    OD1    doub N N 105 
ASP CG    OD2    sing N N 106 
ASP OD2   HD2    sing N N 107 
ASP OXT   HXT    sing N N 108 
C   OP3   P      sing N N 109 
C   OP3   HOP3   sing N N 110 
C   P     OP1    doub N N 111 
C   P     OP2    sing N N 112 
C   P     "O5'"  sing N N 113 
C   OP2   HOP2   sing N N 114 
C   "O5'" "C5'"  sing N N 115 
C   "C5'" "C4'"  sing N N 116 
C   "C5'" "H5'"  sing N N 117 
C   "C5'" "H5''" sing N N 118 
C   "C4'" "O4'"  sing N N 119 
C   "C4'" "C3'"  sing N N 120 
C   "C4'" "H4'"  sing N N 121 
C   "O4'" "C1'"  sing N N 122 
C   "C3'" "O3'"  sing N N 123 
C   "C3'" "C2'"  sing N N 124 
C   "C3'" "H3'"  sing N N 125 
C   "O3'" "HO3'" sing N N 126 
C   "C2'" "O2'"  sing N N 127 
C   "C2'" "C1'"  sing N N 128 
C   "C2'" "H2'"  sing N N 129 
C   "O2'" "HO2'" sing N N 130 
C   "C1'" N1     sing N N 131 
C   "C1'" "H1'"  sing N N 132 
C   N1    C2     sing N N 133 
C   N1    C6     sing N N 134 
C   C2    O2     doub N N 135 
C   C2    N3     sing N N 136 
C   N3    C4     doub N N 137 
C   C4    N4     sing N N 138 
C   C4    C5     sing N N 139 
C   N4    H41    sing N N 140 
C   N4    H42    sing N N 141 
C   C5    C6     doub N N 142 
C   C5    H5     sing N N 143 
C   C6    H6     sing N N 144 
CYS N     CA     sing N N 145 
CYS N     H      sing N N 146 
CYS N     H2     sing N N 147 
CYS CA    C      sing N N 148 
CYS CA    CB     sing N N 149 
CYS CA    HA     sing N N 150 
CYS C     O      doub N N 151 
CYS C     OXT    sing N N 152 
CYS CB    SG     sing N N 153 
CYS CB    HB2    sing N N 154 
CYS CB    HB3    sing N N 155 
CYS SG    HG     sing N N 156 
CYS OXT   HXT    sing N N 157 
G   OP3   P      sing N N 158 
G   OP3   HOP3   sing N N 159 
G   P     OP1    doub N N 160 
G   P     OP2    sing N N 161 
G   P     "O5'"  sing N N 162 
G   OP2   HOP2   sing N N 163 
G   "O5'" "C5'"  sing N N 164 
G   "C5'" "C4'"  sing N N 165 
G   "C5'" "H5'"  sing N N 166 
G   "C5'" "H5''" sing N N 167 
G   "C4'" "O4'"  sing N N 168 
G   "C4'" "C3'"  sing N N 169 
G   "C4'" "H4'"  sing N N 170 
G   "O4'" "C1'"  sing N N 171 
G   "C3'" "O3'"  sing N N 172 
G   "C3'" "C2'"  sing N N 173 
G   "C3'" "H3'"  sing N N 174 
G   "O3'" "HO3'" sing N N 175 
G   "C2'" "O2'"  sing N N 176 
G   "C2'" "C1'"  sing N N 177 
G   "C2'" "H2'"  sing N N 178 
G   "O2'" "HO2'" sing N N 179 
G   "C1'" N9     sing N N 180 
G   "C1'" "H1'"  sing N N 181 
G   N9    C8     sing Y N 182 
G   N9    C4     sing Y N 183 
G   C8    N7     doub Y N 184 
G   C8    H8     sing N N 185 
G   N7    C5     sing Y N 186 
G   C5    C6     sing N N 187 
G   C5    C4     doub Y N 188 
G   C6    O6     doub N N 189 
G   C6    N1     sing N N 190 
G   N1    C2     sing N N 191 
G   N1    H1     sing N N 192 
G   C2    N2     sing N N 193 
G   C2    N3     doub N N 194 
G   N2    H21    sing N N 195 
G   N2    H22    sing N N 196 
G   N3    C4     sing N N 197 
GLN N     CA     sing N N 198 
GLN N     H      sing N N 199 
GLN N     H2     sing N N 200 
GLN CA    C      sing N N 201 
GLN CA    CB     sing N N 202 
GLN CA    HA     sing N N 203 
GLN C     O      doub N N 204 
GLN C     OXT    sing N N 205 
GLN CB    CG     sing N N 206 
GLN CB    HB2    sing N N 207 
GLN CB    HB3    sing N N 208 
GLN CG    CD     sing N N 209 
GLN CG    HG2    sing N N 210 
GLN CG    HG3    sing N N 211 
GLN CD    OE1    doub N N 212 
GLN CD    NE2    sing N N 213 
GLN NE2   HE21   sing N N 214 
GLN NE2   HE22   sing N N 215 
GLN OXT   HXT    sing N N 216 
GLU N     CA     sing N N 217 
GLU N     H      sing N N 218 
GLU N     H2     sing N N 219 
GLU CA    C      sing N N 220 
GLU CA    CB     sing N N 221 
GLU CA    HA     sing N N 222 
GLU C     O      doub N N 223 
GLU C     OXT    sing N N 224 
GLU CB    CG     sing N N 225 
GLU CB    HB2    sing N N 226 
GLU CB    HB3    sing N N 227 
GLU CG    CD     sing N N 228 
GLU CG    HG2    sing N N 229 
GLU CG    HG3    sing N N 230 
GLU CD    OE1    doub N N 231 
GLU CD    OE2    sing N N 232 
GLU OE2   HE2    sing N N 233 
GLU OXT   HXT    sing N N 234 
GLY N     CA     sing N N 235 
GLY N     H      sing N N 236 
GLY N     H2     sing N N 237 
GLY CA    C      sing N N 238 
GLY CA    HA2    sing N N 239 
GLY CA    HA3    sing N N 240 
GLY C     O      doub N N 241 
GLY C     OXT    sing N N 242 
GLY OXT   HXT    sing N N 243 
HIS N     CA     sing N N 244 
HIS N     H      sing N N 245 
HIS N     H2     sing N N 246 
HIS CA    C      sing N N 247 
HIS CA    CB     sing N N 248 
HIS CA    HA     sing N N 249 
HIS C     O      doub N N 250 
HIS C     OXT    sing N N 251 
HIS CB    CG     sing N N 252 
HIS CB    HB2    sing N N 253 
HIS CB    HB3    sing N N 254 
HIS CG    ND1    sing Y N 255 
HIS CG    CD2    doub Y N 256 
HIS ND1   CE1    doub Y N 257 
HIS ND1   HD1    sing N N 258 
HIS CD2   NE2    sing Y N 259 
HIS CD2   HD2    sing N N 260 
HIS CE1   NE2    sing Y N 261 
HIS CE1   HE1    sing N N 262 
HIS NE2   HE2    sing N N 263 
HIS OXT   HXT    sing N N 264 
ILE N     CA     sing N N 265 
ILE N     H      sing N N 266 
ILE N     H2     sing N N 267 
ILE CA    C      sing N N 268 
ILE CA    CB     sing N N 269 
ILE CA    HA     sing N N 270 
ILE C     O      doub N N 271 
ILE C     OXT    sing N N 272 
ILE CB    CG1    sing N N 273 
ILE CB    CG2    sing N N 274 
ILE CB    HB     sing N N 275 
ILE CG1   CD1    sing N N 276 
ILE CG1   HG12   sing N N 277 
ILE CG1   HG13   sing N N 278 
ILE CG2   HG21   sing N N 279 
ILE CG2   HG22   sing N N 280 
ILE CG2   HG23   sing N N 281 
ILE CD1   HD11   sing N N 282 
ILE CD1   HD12   sing N N 283 
ILE CD1   HD13   sing N N 284 
ILE OXT   HXT    sing N N 285 
LEU N     CA     sing N N 286 
LEU N     H      sing N N 287 
LEU N     H2     sing N N 288 
LEU CA    C      sing N N 289 
LEU CA    CB     sing N N 290 
LEU CA    HA     sing N N 291 
LEU C     O      doub N N 292 
LEU C     OXT    sing N N 293 
LEU CB    CG     sing N N 294 
LEU CB    HB2    sing N N 295 
LEU CB    HB3    sing N N 296 
LEU CG    CD1    sing N N 297 
LEU CG    CD2    sing N N 298 
LEU CG    HG     sing N N 299 
LEU CD1   HD11   sing N N 300 
LEU CD1   HD12   sing N N 301 
LEU CD1   HD13   sing N N 302 
LEU CD2   HD21   sing N N 303 
LEU CD2   HD22   sing N N 304 
LEU CD2   HD23   sing N N 305 
LEU OXT   HXT    sing N N 306 
LYS N     CA     sing N N 307 
LYS N     H      sing N N 308 
LYS N     H2     sing N N 309 
LYS CA    C      sing N N 310 
LYS CA    CB     sing N N 311 
LYS CA    HA     sing N N 312 
LYS C     O      doub N N 313 
LYS C     OXT    sing N N 314 
LYS CB    CG     sing N N 315 
LYS CB    HB2    sing N N 316 
LYS CB    HB3    sing N N 317 
LYS CG    CD     sing N N 318 
LYS CG    HG2    sing N N 319 
LYS CG    HG3    sing N N 320 
LYS CD    CE     sing N N 321 
LYS CD    HD2    sing N N 322 
LYS CD    HD3    sing N N 323 
LYS CE    NZ     sing N N 324 
LYS CE    HE2    sing N N 325 
LYS CE    HE3    sing N N 326 
LYS NZ    HZ1    sing N N 327 
LYS NZ    HZ2    sing N N 328 
LYS NZ    HZ3    sing N N 329 
LYS OXT   HXT    sing N N 330 
MET N     CA     sing N N 331 
MET N     H      sing N N 332 
MET N     H2     sing N N 333 
MET CA    C      sing N N 334 
MET CA    CB     sing N N 335 
MET CA    HA     sing N N 336 
MET C     O      doub N N 337 
MET C     OXT    sing N N 338 
MET CB    CG     sing N N 339 
MET CB    HB2    sing N N 340 
MET CB    HB3    sing N N 341 
MET CG    SD     sing N N 342 
MET CG    HG2    sing N N 343 
MET CG    HG3    sing N N 344 
MET SD    CE     sing N N 345 
MET CE    HE1    sing N N 346 
MET CE    HE2    sing N N 347 
MET CE    HE3    sing N N 348 
MET OXT   HXT    sing N N 349 
PHE N     CA     sing N N 350 
PHE N     H      sing N N 351 
PHE N     H2     sing N N 352 
PHE CA    C      sing N N 353 
PHE CA    CB     sing N N 354 
PHE CA    HA     sing N N 355 
PHE C     O      doub N N 356 
PHE C     OXT    sing N N 357 
PHE CB    CG     sing N N 358 
PHE CB    HB2    sing N N 359 
PHE CB    HB3    sing N N 360 
PHE CG    CD1    doub Y N 361 
PHE CG    CD2    sing Y N 362 
PHE CD1   CE1    sing Y N 363 
PHE CD1   HD1    sing N N 364 
PHE CD2   CE2    doub Y N 365 
PHE CD2   HD2    sing N N 366 
PHE CE1   CZ     doub Y N 367 
PHE CE1   HE1    sing N N 368 
PHE CE2   CZ     sing Y N 369 
PHE CE2   HE2    sing N N 370 
PHE CZ    HZ     sing N N 371 
PHE OXT   HXT    sing N N 372 
PRO N     CA     sing N N 373 
PRO N     CD     sing N N 374 
PRO N     H      sing N N 375 
PRO CA    C      sing N N 376 
PRO CA    CB     sing N N 377 
PRO CA    HA     sing N N 378 
PRO C     O      doub N N 379 
PRO C     OXT    sing N N 380 
PRO CB    CG     sing N N 381 
PRO CB    HB2    sing N N 382 
PRO CB    HB3    sing N N 383 
PRO CG    CD     sing N N 384 
PRO CG    HG2    sing N N 385 
PRO CG    HG3    sing N N 386 
PRO CD    HD2    sing N N 387 
PRO CD    HD3    sing N N 388 
PRO OXT   HXT    sing N N 389 
SER N     CA     sing N N 390 
SER N     H      sing N N 391 
SER N     H2     sing N N 392 
SER CA    C      sing N N 393 
SER CA    CB     sing N N 394 
SER CA    HA     sing N N 395 
SER C     O      doub N N 396 
SER C     OXT    sing N N 397 
SER CB    OG     sing N N 398 
SER CB    HB2    sing N N 399 
SER CB    HB3    sing N N 400 
SER OG    HG     sing N N 401 
SER OXT   HXT    sing N N 402 
THR N     CA     sing N N 403 
THR N     H      sing N N 404 
THR N     H2     sing N N 405 
THR CA    C      sing N N 406 
THR CA    CB     sing N N 407 
THR CA    HA     sing N N 408 
THR C     O      doub N N 409 
THR C     OXT    sing N N 410 
THR CB    OG1    sing N N 411 
THR CB    CG2    sing N N 412 
THR CB    HB     sing N N 413 
THR OG1   HG1    sing N N 414 
THR CG2   HG21   sing N N 415 
THR CG2   HG22   sing N N 416 
THR CG2   HG23   sing N N 417 
THR OXT   HXT    sing N N 418 
TRP N     CA     sing N N 419 
TRP N     H      sing N N 420 
TRP N     H2     sing N N 421 
TRP CA    C      sing N N 422 
TRP CA    CB     sing N N 423 
TRP CA    HA     sing N N 424 
TRP C     O      doub N N 425 
TRP C     OXT    sing N N 426 
TRP CB    CG     sing N N 427 
TRP CB    HB2    sing N N 428 
TRP CB    HB3    sing N N 429 
TRP CG    CD1    doub Y N 430 
TRP CG    CD2    sing Y N 431 
TRP CD1   NE1    sing Y N 432 
TRP CD1   HD1    sing N N 433 
TRP CD2   CE2    doub Y N 434 
TRP CD2   CE3    sing Y N 435 
TRP NE1   CE2    sing Y N 436 
TRP NE1   HE1    sing N N 437 
TRP CE2   CZ2    sing Y N 438 
TRP CE3   CZ3    doub Y N 439 
TRP CE3   HE3    sing N N 440 
TRP CZ2   CH2    doub Y N 441 
TRP CZ2   HZ2    sing N N 442 
TRP CZ3   CH2    sing Y N 443 
TRP CZ3   HZ3    sing N N 444 
TRP CH2   HH2    sing N N 445 
TRP OXT   HXT    sing N N 446 
TYR N     CA     sing N N 447 
TYR N     H      sing N N 448 
TYR N     H2     sing N N 449 
TYR CA    C      sing N N 450 
TYR CA    CB     sing N N 451 
TYR CA    HA     sing N N 452 
TYR C     O      doub N N 453 
TYR C     OXT    sing N N 454 
TYR CB    CG     sing N N 455 
TYR CB    HB2    sing N N 456 
TYR CB    HB3    sing N N 457 
TYR CG    CD1    doub Y N 458 
TYR CG    CD2    sing Y N 459 
TYR CD1   CE1    sing Y N 460 
TYR CD1   HD1    sing N N 461 
TYR CD2   CE2    doub Y N 462 
TYR CD2   HD2    sing N N 463 
TYR CE1   CZ     doub Y N 464 
TYR CE1   HE1    sing N N 465 
TYR CE2   CZ     sing Y N 466 
TYR CE2   HE2    sing N N 467 
TYR CZ    OH     sing N N 468 
TYR OH    HH     sing N N 469 
TYR OXT   HXT    sing N N 470 
U   OP3   P      sing N N 471 
U   OP3   HOP3   sing N N 472 
U   P     OP1    doub N N 473 
U   P     OP2    sing N N 474 
U   P     "O5'"  sing N N 475 
U   OP2   HOP2   sing N N 476 
U   "O5'" "C5'"  sing N N 477 
U   "C5'" "C4'"  sing N N 478 
U   "C5'" "H5'"  sing N N 479 
U   "C5'" "H5''" sing N N 480 
U   "C4'" "O4'"  sing N N 481 
U   "C4'" "C3'"  sing N N 482 
U   "C4'" "H4'"  sing N N 483 
U   "O4'" "C1'"  sing N N 484 
U   "C3'" "O3'"  sing N N 485 
U   "C3'" "C2'"  sing N N 486 
U   "C3'" "H3'"  sing N N 487 
U   "O3'" "HO3'" sing N N 488 
U   "C2'" "O2'"  sing N N 489 
U   "C2'" "C1'"  sing N N 490 
U   "C2'" "H2'"  sing N N 491 
U   "O2'" "HO2'" sing N N 492 
U   "C1'" N1     sing N N 493 
U   "C1'" "H1'"  sing N N 494 
U   N1    C2     sing N N 495 
U   N1    C6     sing N N 496 
U   C2    O2     doub N N 497 
U   C2    N3     sing N N 498 
U   N3    C4     sing N N 499 
U   N3    H3     sing N N 500 
U   C4    O4     doub N N 501 
U   C4    C5     sing N N 502 
U   C5    C6     doub N N 503 
U   C5    H5     sing N N 504 
U   C6    H6     sing N N 505 
VAL N     CA     sing N N 506 
VAL N     H      sing N N 507 
VAL N     H2     sing N N 508 
VAL CA    C      sing N N 509 
VAL CA    CB     sing N N 510 
VAL CA    HA     sing N N 511 
VAL C     O      doub N N 512 
VAL C     OXT    sing N N 513 
VAL CB    CG1    sing N N 514 
VAL CB    CG2    sing N N 515 
VAL CB    HB     sing N N 516 
VAL CG1   HG11   sing N N 517 
VAL CG1   HG12   sing N N 518 
VAL CG1   HG13   sing N N 519 
VAL CG2   HG21   sing N N 520 
VAL CG2   HG22   sing N N 521 
VAL CG2   HG23   sing N N 522 
VAL OXT   HXT    sing N N 523 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-02-21 
_em_admin.deposition_site    RCSB 
_em_admin.entry_id           8W2S 
_em_admin.last_update        2025-06-04 
_em_admin.map_release_date   2025-01-15 
_em_admin.title              'Cas9d Effector:sgRNA Binary Complex' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_molwt.entity_assembly_id   1 
_em_entity_assembly_molwt.experimental_flag    NO 
_em_entity_assembly_molwt.id                   1 
_em_entity_assembly_molwt.units                MEGADALTONS 
_em_entity_assembly_molwt.value                0.13734 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          28221 
_em_entity_assembly_naturalsource.organism             Deltaproteobacteria 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          562 
_em_entity_assembly_recombinant.organism             'Escherichia coli' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               'NICO DE3' 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         80 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'            ? 1  1 ? ? ?      ? 
'IMAGE ACQUISITION'             ? 2  ? ? 1 ?      ? 
MASKING                         ? 3  ? ? ? ?      ? 
'CTF CORRECTION'                ? 4  1 ? ? ?      ? 
'LAYERLINE INDEXING'            ? 5  ? ? ? ?      ? 
'DIFFRACTION INDEXING'          ? 6  ? ? ? ?      ? 
'MODEL FITTING'                 ? 7  ? ? ? ?      ? 
'MODEL REFINEMENT'              ? 8  ? ? ? PHENIX ? 
OTHER                           ? 9  ? ? ? ?      ? 
'INITIAL EULER ASSIGNMENT'      ? 10 1 ? ? ?      ? 
'FINAL EULER ASSIGNMENT'        ? 11 1 ? ? ?      ? 
CLASSIFICATION                  ? 12 1 ? ? ?      ? 
RECONSTRUCTION                  ? 13 1 ? ? ?      ? 
'VOLUME SELECTION'              ? 14 1 1 1 ?      ? 
'SERIES ALIGNMENT'              ? 15 1 1 1 ?      ? 
'MOLECULAR REPLACEMENT'         ? 16 1 1 1 ?      ? 
'LATTICE DISTORTION CORRECTION' ? 17 1 1 1 ?      ? 
'SYMMETRY DETERMINATION'        ? 18 1 1 1 ?      ? 
'CRYSTALLOGRAPHY MERGING'       ? 19 1 1 1 ?      ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
loop_
_ndb_struct_conf_na.entry_id 
_ndb_struct_conf_na.feature 
8W2S 'double helix'        
8W2S 'a-form double helix' 
# 
loop_
_ndb_struct_na_base_pair.model_number 
_ndb_struct_na_base_pair.i_label_asym_id 
_ndb_struct_na_base_pair.i_label_comp_id 
_ndb_struct_na_base_pair.i_label_seq_id 
_ndb_struct_na_base_pair.i_symmetry 
_ndb_struct_na_base_pair.j_label_asym_id 
_ndb_struct_na_base_pair.j_label_comp_id 
_ndb_struct_na_base_pair.j_label_seq_id 
_ndb_struct_na_base_pair.j_symmetry 
_ndb_struct_na_base_pair.shear 
_ndb_struct_na_base_pair.stretch 
_ndb_struct_na_base_pair.stagger 
_ndb_struct_na_base_pair.buckle 
_ndb_struct_na_base_pair.propeller 
_ndb_struct_na_base_pair.opening 
_ndb_struct_na_base_pair.pair_number 
_ndb_struct_na_base_pair.pair_name 
_ndb_struct_na_base_pair.i_auth_asym_id 
_ndb_struct_na_base_pair.i_auth_seq_id 
_ndb_struct_na_base_pair.i_PDB_ins_code 
_ndb_struct_na_base_pair.j_auth_asym_id 
_ndb_struct_na_base_pair.j_auth_seq_id 
_ndb_struct_na_base_pair.j_PDB_ins_code 
_ndb_struct_na_base_pair.hbond_type_28 
_ndb_struct_na_base_pair.hbond_type_12 
1 B G 21  1_555 B A 58  1_555 -0.339 1.361  -0.418 -1.354  1.607   -8.457   1  B_G21:A58_B   B 21  ? B 58  ? 8  1  
1 B U 22  1_555 B A 57  1_555 0.005  -0.069 0.176  1.983   3.891   -0.178   2  B_U22:A57_B   B 22  ? B 57  ? 20 1  
1 B U 23  1_555 B A 56  1_555 -0.059 -0.139 0.353  -0.581  -7.516  4.995    3  B_U23:A56_B   B 23  ? B 56  ? 20 1  
1 B A 24  1_555 B U 55  1_555 -0.008 -0.104 -0.074 -6.587  -3.986  -0.145   4  B_A24:U55_B   B 24  ? B 55  ? 20 1  
1 B C 25  1_555 B G 54  1_555 0.215  -0.122 0.031  1.651   -3.543  1.081    5  B_C25:G54_B   B 25  ? B 54  ? 19 1  
1 B A 26  1_555 B U 53  1_555 0.145  -0.115 0.260  3.408   -1.259  3.250    6  B_A26:U53_B   B 26  ? B 53  ? 20 1  
1 B G 27  1_555 B U 52  1_555 -1.152 -0.365 -0.091 1.215   1.092   2.038    7  B_G27:U52_B   B 27  ? B 52  ? 28 1  
1 B U 28  1_555 B A 51  1_555 0.007  -0.139 -0.211 3.777   1.401   1.728    8  B_U28:A51_B   B 28  ? B 51  ? 20 1  
1 B U 29  1_555 B A 50  1_555 -0.091 -0.050 -0.111 1.954   -4.720  0.501    9  B_U29:A50_B   B 29  ? B 50  ? 20 1  
1 B A 30  1_555 B U 49  1_555 0.035  -0.085 0.141  -4.336  -1.347  1.432    10 B_A30:U49_B   B 30  ? B 49  ? 20 1  
1 B A 31  1_555 B U 48  1_555 0.040  -0.113 -0.153 -0.578  4.214   1.355    11 B_A31:U48_B   B 31  ? B 48  ? 20 1  
1 B G 32  1_555 B C 47  1_555 -0.176 -0.238 -0.899 -5.817  -4.360  0.531    12 B_G32:C47_B   B 32  ? B 47  ? 19 1  
1 B G 33  1_555 B C 46  1_555 -0.116 -0.198 -0.673 -7.063  4.632   -1.399   13 B_G33:C46_B   B 33  ? B 46  ? 19 1  
1 B C 34  1_555 B G 45  1_555 0.182  -0.164 -0.230 -0.996  7.635   -0.126   14 B_C34:G45_B   B 34  ? B 45  ? 19 1  
1 B U 35  1_555 B A 44  1_555 -0.026 -0.086 -0.082 0.783   6.655   -0.382   15 B_U35:A44_B   B 35  ? B 44  ? 20 1  
1 B C 36  1_555 B G 43  1_555 0.210  -0.183 -0.006 3.836   6.499   -0.262   16 B_C36:G43_B   B 36  ? B 43  ? 19 1  
1 B U 37  1_555 B A 42  1_555 -0.031 -0.080 -0.227 -0.291  -4.525  0.091    17 B_U37:A42_B   B 37  ? B 42  ? 20 1  
1 B G 38  1_555 B A 41  1_555 7.525  -5.454 0.790  31.445  12.926  -35.797  18 B_G38:A41_B   B 38  ? B 41  ? ?  ?  
1 B C 60  1_555 B U 140 1_555 -6.819 -5.353 -0.428 -21.761 -27.251 -43.821  19 B_C60:U140_B  B 60  ? B 140 ? ?  10 
1 B G 61  1_555 B U 139 1_555 -1.931 -0.595 -1.227 -14.204 2.281   -9.635   20 B_G61:U139_B  B 61  ? B 139 ? 28 1  
1 B C 62  1_555 B G 138 1_555 0.162  -0.205 -0.516 0.522   9.479   -4.363   21 B_C62:G138_B  B 62  ? B 138 ? 19 1  
1 B C 63  1_555 B G 137 1_555 0.210  -0.129 -0.323 0.039   -3.525  0.173    22 B_C63:G137_B  B 63  ? B 137 ? 19 1  
1 B U 64  1_555 B G 136 1_555 1.888  -0.373 -0.335 4.127   2.927   4.345    23 B_U64:G136_B  B 64  ? B 136 ? 28 1  
1 B A 67  1_555 B U 135 1_555 -0.052 -0.143 0.268  -3.317  -3.051  3.799    24 B_A67:U135_B  B 67  ? B 135 ? 20 1  
1 B C 68  1_555 B G 134 1_555 0.216  -0.132 0.341  0.319   -1.178  1.688    25 B_C68:G134_B  B 68  ? B 134 ? 19 1  
1 B G 70  1_555 B U 132 1_555 -1.174 -0.320 -0.385 -5.398  -0.774  2.483    26 B_G70:U132_B  B 70  ? B 132 ? 28 1  
1 B U 71  1_555 B A 131 1_555 -0.060 -0.099 -0.203 1.477   -2.156  -0.368   27 B_U71:A131_B  B 71  ? B 131 ? 20 1  
1 B G 72  1_555 B C 130 1_555 -0.150 -0.141 -0.175 -6.463  -0.233  -1.114   28 B_G72:C130_B  B 72  ? B 130 ? 19 1  
1 B A 73  1_555 B U 129 1_555 0.085  -0.096 -0.031 -2.567  3.820   -0.768   29 B_A73:U129_B  B 73  ? B 129 ? 20 1  
1 B A 74  1_555 B U 128 1_555 0.090  -0.125 0.112  0.343   4.266   0.452    30 B_A74:U128_B  B 74  ? B 128 ? 20 1  
1 B G 75  1_555 B C 127 1_555 -0.151 -0.136 0.007  1.372   1.364   0.930    31 B_G75:C127_B  B 75  ? B 127 ? 19 1  
1 B G 76  1_555 B C 126 1_555 -0.166 -0.104 -0.296 -2.205  -3.343  -0.096   32 B_G76:C126_B  B 76  ? B 126 ? 19 1  
1 B G 77  1_555 B G 125 1_555 6.614  -2.052 -0.702 -6.569  -2.094  -14.208  33 B_G77:G125_B  B 77  ? B 125 ? ?  3  
1 B G 113 1_555 B C 124 1_555 -0.147 -0.102 -0.274 1.748   -0.544  0.421    34 B_G113:C124_B B 113 ? B 124 ? 19 1  
1 B C 114 1_555 B G 123 1_555 0.177  -0.185 -0.761 3.859   0.959   1.481    35 B_C114:G123_B B 114 ? B 123 ? 19 1  
1 B C 115 1_555 B G 122 1_555 0.210  -0.186 -0.592 2.089   -0.025  -0.380   36 B_C115:G122_B B 115 ? B 122 ? 19 1  
1 B A 116 1_555 B U 121 1_555 0.112  -0.053 -0.220 -2.597  7.671   -2.491   37 B_A116:U121_B B 116 ? B 121 ? 20 1  
1 B G 117 1_555 B A 120 1_555 7.561  -5.646 0.771  21.600  -4.454  -31.004  38 B_G117:A120_B B 117 ? B 120 ? ?  ?  
1 B A 80  1_555 B U 112 1_555 -0.038 -0.025 0.244  -2.701  -4.030  2.300    39 B_A80:U112_B  B 80  ? B 112 ? 20 1  
1 B U 81  1_555 B A 111 1_555 -0.155 -0.106 0.264  5.778   -8.699  -1.741   40 B_U81:A111_B  B 81  ? B 111 ? 20 1  
1 B A 82  1_555 B U 110 1_555 0.102  -0.198 0.523  -0.397  -14.687 -0.423   41 B_A82:U110_B  B 82  ? B 110 ? 20 1  
1 B C 107 1_555 B C 109 1_555 5.386  1.590  0.856  -16.187 -2.039  -37.965  42 B_C107:C109_B B 107 ? B 109 ? ?  ?  
1 B G 84  1_555 B C 106 1_555 -0.165 -0.264 -1.341 -15.451 -5.394  -1.333   43 B_G84:C106_B  B 84  ? B 106 ? 19 1  
1 B C 85  1_555 B G 105 1_555 0.157  -0.272 -0.635 -7.393  -0.486  -3.062   44 B_C85:G105_B  B 85  ? B 105 ? 19 1  
1 B U 86  1_555 B A 104 1_555 -0.033 -0.094 -0.349 -1.700  4.228   -4.105   45 B_U86:A104_B  B 86  ? B 104 ? 20 1  
1 B U 87  1_555 B G 103 1_555 2.696  -0.560 0.174  3.769   3.509   -6.337   46 B_U87:G103_B  B 87  ? B 103 ? 28 1  
1 B G 88  1_555 B U 102 1_555 -2.073 -0.425 -0.565 -6.907  -4.858  -1.384   47 B_G88:U102_B  B 88  ? B 102 ? 28 1  
1 B G 89  1_555 B C 101 1_555 -0.203 -0.155 -0.635 -5.927  -4.750  0.749    48 B_G89:C101_B  B 89  ? B 101 ? 19 1  
1 B G 90  1_555 B C 100 1_555 -0.202 -0.161 -0.326 -3.365  5.330   0.810    49 B_G90:C100_B  B 90  ? B 100 ? 19 1  
1 B U 91  1_555 B G 99  1_555 1.788  -0.446 -0.347 9.551   4.311   -0.394   50 B_U91:G99_B   B 91  ? B 99  ? 28 1  
1 B U 92  1_555 B A 98  1_555 2.287  2.669  -0.098 16.451  5.466   -111.872 51 B_U92:A98_B   B 92  ? B 98  ? ?  ?  
1 B G 142 1_555 B C 97  1_555 0.283  2.367  1.139  4.524   0.260   151.288  52 B_G142:C97_B  B 142 ? B 97  ? 22 2  
1 B G 143 1_555 B C 96  1_555 -0.197 -0.158 -0.396 -6.155  2.829   -4.196   53 B_G143:C96_B  B 143 ? B 96  ? 19 1  
1 B A 144 1_555 B U 95  1_555 0.087  -0.213 -0.920 -0.900  1.793   -0.239   54 B_A144:U95_B  B 144 ? B 95  ? 20 1  
1 B C 145 1_555 B G 94  1_555 0.172  -0.288 -1.078 7.369   -2.734  0.664    55 B_C145:G94_B  B 145 ? B 94  ? 19 1  
# 
loop_
_ndb_struct_na_base_pair_step.model_number 
_ndb_struct_na_base_pair_step.i_label_asym_id_1 
_ndb_struct_na_base_pair_step.i_label_comp_id_1 
_ndb_struct_na_base_pair_step.i_label_seq_id_1 
_ndb_struct_na_base_pair_step.i_symmetry_1 
_ndb_struct_na_base_pair_step.j_label_asym_id_1 
_ndb_struct_na_base_pair_step.j_label_comp_id_1 
_ndb_struct_na_base_pair_step.j_label_seq_id_1 
_ndb_struct_na_base_pair_step.j_symmetry_1 
_ndb_struct_na_base_pair_step.i_label_asym_id_2 
_ndb_struct_na_base_pair_step.i_label_comp_id_2 
_ndb_struct_na_base_pair_step.i_label_seq_id_2 
_ndb_struct_na_base_pair_step.i_symmetry_2 
_ndb_struct_na_base_pair_step.j_label_asym_id_2 
_ndb_struct_na_base_pair_step.j_label_comp_id_2 
_ndb_struct_na_base_pair_step.j_label_seq_id_2 
_ndb_struct_na_base_pair_step.j_symmetry_2 
_ndb_struct_na_base_pair_step.shift 
_ndb_struct_na_base_pair_step.slide 
_ndb_struct_na_base_pair_step.rise 
_ndb_struct_na_base_pair_step.tilt 
_ndb_struct_na_base_pair_step.roll 
_ndb_struct_na_base_pair_step.twist 
_ndb_struct_na_base_pair_step.x_displacement 
_ndb_struct_na_base_pair_step.y_displacement 
_ndb_struct_na_base_pair_step.helical_rise 
_ndb_struct_na_base_pair_step.inclination 
_ndb_struct_na_base_pair_step.tip 
_ndb_struct_na_base_pair_step.helical_twist 
_ndb_struct_na_base_pair_step.step_number 
_ndb_struct_na_base_pair_step.step_name 
_ndb_struct_na_base_pair_step.i_auth_asym_id_1 
_ndb_struct_na_base_pair_step.i_auth_seq_id_1 
_ndb_struct_na_base_pair_step.i_PDB_ins_code_1 
_ndb_struct_na_base_pair_step.j_auth_asym_id_1 
_ndb_struct_na_base_pair_step.j_auth_seq_id_1 
_ndb_struct_na_base_pair_step.j_PDB_ins_code_1 
_ndb_struct_na_base_pair_step.i_auth_asym_id_2 
_ndb_struct_na_base_pair_step.i_auth_seq_id_2 
_ndb_struct_na_base_pair_step.i_PDB_ins_code_2 
_ndb_struct_na_base_pair_step.j_auth_asym_id_2 
_ndb_struct_na_base_pair_step.j_auth_seq_id_2 
_ndb_struct_na_base_pair_step.j_PDB_ins_code_2 
1 B G 21  1_555 B A 58  1_555 B U 22  1_555 B A 57  1_555 0.279  -1.806 3.275  -6.078  4.548    30.415   -4.163  -1.611 2.873  
8.503   11.364  31.326   1  BB_G21U22:A57A58_BB     B 21  ? B 58  ? B 22  ? B 57  ? 
1 B U 22  1_555 B A 57  1_555 B U 23  1_555 B A 56  1_555 0.795  -1.920 3.098  0.871   10.686   34.786   -4.368  -1.169 2.440  
17.371  -1.416  36.352   2  BB_U22U23:A56A57_BB     B 22  ? B 57  ? B 23  ? B 56  ? 
1 B U 23  1_555 B A 56  1_555 B A 24  1_555 B U 55  1_555 -0.795 -1.562 3.139  -0.160  12.034   32.816   -4.211  1.304  2.437  
20.463  0.272   34.897   3  BB_U23A24:U55A56_BB     B 23  ? B 56  ? B 24  ? B 55  ? 
1 B A 24  1_555 B U 55  1_555 B C 25  1_555 B G 54  1_555 -0.012 -1.292 3.177  -2.091  5.084    30.923   -3.285  -0.347 2.927  
9.442   3.883   31.396   4  BB_A24C25:G54U55_BB     B 24  ? B 55  ? B 25  ? B 54  ? 
1 B C 25  1_555 B G 54  1_555 B A 26  1_555 B U 53  1_555 0.363  -1.555 2.992  -1.417  10.602   29.989   -4.457  -0.878 2.304  
19.716  2.634   31.798   5  BB_C25A26:U53G54_BB     B 25  ? B 54  ? B 26  ? B 53  ? 
1 B A 26  1_555 B U 53  1_555 B G 27  1_555 B U 52  1_555 0.073  -2.148 3.176  -0.462  9.081    25.685   -6.525  -0.254 2.294  
19.658  1.001   27.222   6  BB_A26G27:U52U53_BB     B 26  ? B 53  ? B 27  ? B 52  ? 
1 B G 27  1_555 B U 52  1_555 B U 28  1_555 B A 51  1_555 -0.136 -1.598 3.276  0.427   2.674    36.249   -2.928  0.277  3.152  
4.290   -0.684  36.346   7  BB_G27U28:A51U52_BB     B 27  ? B 52  ? B 28  ? B 51  ? 
1 B U 28  1_555 B A 51  1_555 B U 29  1_555 B A 50  1_555 0.159  -1.538 3.301  3.105   5.002    32.137   -3.582  0.243  3.036  
8.941   -5.550  32.658   8  BB_U28U29:A50A51_BB     B 28  ? B 51  ? B 29  ? B 50  ? 
1 B U 29  1_555 B A 50  1_555 B A 30  1_555 B U 49  1_555 -0.087 -1.417 3.077  -2.459  17.672   33.351   -4.121  -0.134 2.093  
28.406  3.953   37.704   9  BB_U29A30:U49A50_BB     B 29  ? B 50  ? B 30  ? B 49  ? 
1 B A 30  1_555 B U 49  1_555 B A 31  1_555 B U 48  1_555 -0.035 -1.541 3.322  -1.050  4.057    31.502   -3.549  -0.126 3.103  
7.431   1.923   31.772   10 BB_A30A31:U48U49_BB     B 30  ? B 49  ? B 31  ? B 48  ? 
1 B A 31  1_555 B U 48  1_555 B G 32  1_555 B C 47  1_555 0.316  -1.876 3.507  6.229   9.916    30.108   -5.132  0.533  2.775  
18.245  -11.460 32.256   11 BB_A31G32:C47U48_BB     B 31  ? B 48  ? B 32  ? B 47  ? 
1 B G 32  1_555 B C 47  1_555 B G 33  1_555 B C 46  1_555 -0.059 -1.643 3.343  -2.985  7.727    31.924   -4.166  -0.387 2.872  
13.761  5.316   32.954   12 BB_G32G33:C46C47_BB     B 32  ? B 47  ? B 33  ? B 46  ? 
1 B G 33  1_555 B C 46  1_555 B C 34  1_555 B G 45  1_555 0.187  -1.749 3.242  -1.858  3.774    35.145   -3.412  -0.571 3.030  
6.222   3.063   35.388   13 BB_G33C34:G45C46_BB     B 33  ? B 46  ? B 34  ? B 45  ? 
1 B C 34  1_555 B G 45  1_555 B U 35  1_555 B A 44  1_555 0.149  -1.704 3.256  1.143   6.068    29.744   -4.407  -0.067 2.864  
11.663  -2.197  30.364   14 BB_C34U35:A44G45_BB     B 34  ? B 45  ? B 35  ? B 44  ? 
1 B U 35  1_555 B A 44  1_555 B C 36  1_555 B G 43  1_555 0.057  -1.579 3.204  1.282   5.021    32.499   -3.598  0.106  2.934  
8.902   -2.272  32.898   15 BB_U35C36:G43A44_BB     B 35  ? B 44  ? B 36  ? B 43  ? 
1 B C 36  1_555 B G 43  1_555 B U 37  1_555 B A 42  1_555 0.578  -1.520 3.246  4.976   10.906   33.611   -3.968  -0.267 2.695  
18.157  -8.284  35.626   16 BB_C36U37:A42G43_BB     B 36  ? B 43  ? B 37  ? B 42  ? 
1 B U 37  1_555 B A 42  1_555 B G 38  1_555 B A 41  1_555 -3.437 -1.068 2.406  -10.043 -0.775   57.845   -1.058  3.081  2.927  
-0.795  10.297  58.640   17 BB_U37G38:A41A42_BB     B 37  ? B 42  ? B 38  ? B 41  ? 
1 B C 60  1_555 B U 140 1_555 B G 61  1_555 B U 139 1_555 2.984  -1.427 3.703  4.028   9.658    46.097   -2.671  -3.355 3.585  
12.151  -5.067  47.207   18 BB_C60G61:U139U140_BB   B 60  ? B 140 ? B 61  ? B 139 ? 
1 B G 61  1_555 B U 139 1_555 B C 62  1_555 B G 138 1_555 0.163  -1.004 3.114  -6.569  6.435    38.383   -2.192  -0.960 2.850  
9.620   9.820   39.429   19 BB_G61C62:G138U139_BB   B 61  ? B 139 ? B 62  ? B 138 ? 
1 B C 62  1_555 B G 138 1_555 B C 63  1_555 B G 137 1_555 0.685  -1.935 3.087  2.445   13.324   31.947   -4.971  -0.835 2.176  
22.960  -4.213  34.631   20 BB_C62C63:G137G138_BB   B 62  ? B 138 ? B 63  ? B 137 ? 
1 B C 63  1_555 B G 137 1_555 B U 64  1_555 B G 136 1_555 0.456  -1.817 3.548  -1.524  -3.444   33.956   -2.488  -1.044 3.686  
-5.874  2.600   34.158   21 BB_C63U64:G136G137_BB   B 63  ? B 137 ? B 64  ? B 136 ? 
1 B A 67  1_555 B U 135 1_555 B C 68  1_555 B G 134 1_555 0.201  -1.500 3.231  -0.097  2.966    34.960   -2.919  -0.347 3.097  
4.925   0.161   35.082   22 BB_A67C68:G134U135_BB   B 67  ? B 135 ? B 68  ? B 134 ? 
1 B C 68  1_555 B G 134 1_555 B G 70  1_555 B U 132 1_555 -0.664 -3.645 6.094  -1.113  19.497   51.048   -5.986  0.612  4.537  
21.735  1.241   54.421   23 BB_C68G70:U132G134_BB   B 68  ? B 134 ? B 70  ? B 132 ? 
1 B G 70  1_555 B U 132 1_555 B U 71  1_555 B A 131 1_555 -0.347 -1.277 3.164  -1.632  2.374    36.565   -2.340  0.338  3.090  
3.776   2.596   36.675   24 BB_G70U71:A131U132_BB   B 70  ? B 132 ? B 71  ? B 131 ? 
1 B U 71  1_555 B A 131 1_555 B G 72  1_555 B C 130 1_555 -0.060 -1.439 3.236  -0.509  16.541   31.552   -4.508  0.033  2.231  
28.129  0.865   35.531   25 BB_U71G72:C130A131_BB   B 71  ? B 131 ? B 72  ? B 130 ? 
1 B G 72  1_555 B C 130 1_555 B A 73  1_555 B U 129 1_555 -0.071 -1.397 3.151  -2.901  4.743    33.314   -3.124  -0.317 2.925  
8.202   5.016   33.762   26 BB_G72A73:U129C130_BB   B 72  ? B 130 ? B 73  ? B 129 ? 
1 B A 73  1_555 B U 129 1_555 B A 74  1_555 B U 128 1_555 0.171  -1.623 3.129  -1.985  6.351    32.188   -3.858  -0.612 2.752  
11.304  3.534   32.851   27 BB_A73A74:U128U129_BB   B 73  ? B 129 ? B 74  ? B 128 ? 
1 B A 74  1_555 B U 128 1_555 B G 75  1_555 B C 127 1_555 0.286  -1.717 3.166  0.436   6.378    30.574   -4.300  -0.456 2.764  
11.931  -0.816  31.220   28 BB_A74G75:C127U128_BB   B 74  ? B 128 ? B 75  ? B 127 ? 
1 B G 75  1_555 B C 127 1_555 B G 76  1_555 B C 126 1_555 0.217  -1.740 3.224  2.259   5.945    34.120   -3.778  -0.037 2.897  
10.025  -3.809  34.690   29 BB_G75G76:C126C127_BB   B 75  ? B 127 ? B 76  ? B 126 ? 
1 B G 76  1_555 B C 126 1_555 B G 77  1_555 B G 125 1_555 -1.076 -1.278 3.507  6.206   1.479    62.595   -1.295  1.324  3.370  
1.420   -5.956  62.886   30 BB_G76G77:G125C126_BB   B 76  ? B 126 ? B 77  ? B 125 ? 
1 B G 77  1_555 B G 125 1_555 B G 113 1_555 B C 124 1_555 -4.883 0.282  3.420  10.497  1.993    54.364   0.197   5.823  2.518  
2.158   -11.365 55.325   31 BB_G77G113:C124G125_BB  B 77  ? B 125 ? B 113 ? B 124 ? 
1 B G 113 1_555 B C 124 1_555 B C 114 1_555 B G 123 1_555 -0.094 -2.296 3.247  2.272   0.066    33.296   -4.009  0.538  3.229  
0.115   -3.960  33.371   32 BB_G113C114:G123C124_BB B 113 ? B 124 ? B 114 ? B 123 ? 
1 B C 114 1_555 B G 123 1_555 B C 115 1_555 B G 122 1_555 0.191  -1.804 3.508  4.362   4.956    30.420   -4.344  0.506  3.178  
9.307   -8.192  31.112   33 BB_C114C115:G122G123_BB B 114 ? B 123 ? B 115 ? B 122 ? 
1 B C 115 1_555 B G 122 1_555 B A 116 1_555 B U 121 1_555 0.066  -1.475 3.401  -0.930  16.650   31.097   -4.759  -0.238 2.333  
28.624  1.598   35.189   34 BB_C115A116:U121G122_BB B 115 ? B 122 ? B 116 ? B 121 ? 
1 B A 116 1_555 B U 121 1_555 B G 117 1_555 B A 120 1_555 -2.463 -1.207 2.615  -5.229  5.920    56.472   -1.531  2.347  2.686  
6.223   5.497   56.976   35 BB_A116G117:A120U121_BB B 116 ? B 121 ? B 117 ? B 120 ? 
1 B A 80  1_555 B U 112 1_555 B U 81  1_555 B A 111 1_555 -0.669 -1.681 3.179  -4.002  3.274    24.525   -4.800  0.410  3.002  
7.599   9.289   25.056   36 BB_A80U81:A111U112_BB   B 80  ? B 112 ? B 81  ? B 111 ? 
1 B U 81  1_555 B A 111 1_555 B A 82  1_555 B U 110 1_555 -0.186 -1.534 2.921  -5.162  18.710   38.328   -3.597  -0.157 2.004  
26.526  7.318   42.797   37 BB_U81A82:U110A111_BB   B 81  ? B 111 ? B 82  ? B 110 ? 
1 B A 82  1_555 B U 110 1_555 B C 107 1_555 B C 109 1_555 -1.992 2.334  0.457  142.204 102.180  -120.836 -1.243  -0.891 0.523  
-51.276 71.361  -177.585 38 BB_A82C107:C109U110_BB  B 82  ? B 110 ? B 107 ? B 109 ? 
1 B C 107 1_555 B C 109 1_555 B G 84  1_555 B C 106 1_555 2.463  -3.601 -1.406 149.833 -43.914  3.607    -1.573  -0.345 3.330  
-25.206 -86.001 156.147  39 BB_C107G84:C106C109_BB  B 107 ? B 109 ? B 84  ? B 106 ? 
1 B G 84  1_555 B C 106 1_555 B C 85  1_555 B G 105 1_555 -0.866 -1.089 3.229  -9.513  5.110    34.891   -2.447  0.065  3.165  
8.280   15.415  36.474   40 BB_G84C85:G105C106_BB   B 84  ? B 106 ? B 85  ? B 105 ? 
1 B C 85  1_555 B G 105 1_555 B U 86  1_555 B A 104 1_555 0.112  -1.207 3.100  -1.093  9.342    31.249   -3.606  -0.370 2.634  
16.869  1.974   32.600   41 BB_C85U86:A104G105_BB   B 85  ? B 105 ? B 86  ? B 104 ? 
1 B U 86  1_555 B A 104 1_555 B U 87  1_555 B G 103 1_555 0.790  -1.105 3.255  2.366   7.011    44.364   -2.064  -0.824 3.091  
9.208   -3.107  44.946   42 BB_U86U87:G103A104_BB   B 86  ? B 104 ? B 87  ? B 103 ? 
1 B U 87  1_555 B G 103 1_555 B G 88  1_555 B U 102 1_555 1.411  -2.598 3.058  13.411  20.054   12.764   -8.989  -0.671 0.231  
51.969  -34.754 27.249   43 BB_U87G88:U102G103_BB   B 87  ? B 103 ? B 88  ? B 102 ? 
1 B G 88  1_555 B U 102 1_555 B G 89  1_555 B C 101 1_555 -0.007 -1.698 3.617  -1.106  1.761    34.429   -3.162  -0.175 3.527  
2.972   1.866   34.490   44 BB_G88G89:C101U102_BB   B 88  ? B 102 ? B 89  ? B 101 ? 
1 B G 89  1_555 B C 101 1_555 B G 90  1_555 B C 100 1_555 -0.267 -1.592 3.118  -2.614  11.703   33.840   -4.064  0.105  2.464  
19.366  4.325   35.843   45 BB_G89G90:C100C101_BB   B 89  ? B 101 ? B 90  ? B 100 ? 
1 B G 90  1_555 B C 100 1_555 B U 91  1_555 B G 99  1_555 0.355  -1.126 3.181  4.201   6.979    34.742   -2.797  -0.004 2.929  
11.493  -6.918  35.656   46 BB_G90U91:G99C100_BB    B 90  ? B 100 ? B 91  ? B 99  ? 
1 B U 91  1_555 B G 99  1_555 B U 92  1_555 B A 98  1_555 -1.305 0.061  3.539  4.966   4.388    -0.461   -25.681 17.212 1.181  
-56.961 64.469  -6.643   47 BB_U91U92:A98G99_BB     B 91  ? B 99  ? B 92  ? B 98  ? 
1 B U 92  1_555 B A 98  1_555 B G 142 1_555 B C 97  1_555 2.161  3.949  1.465  153.314 20.394   -119.947 -2.012  1.275  -0.032 
-10.415 78.298  -167.400 48 BB_U92G142:C97A98_BB    B 92  ? B 98  ? B 142 ? B 97  ? 
1 B G 142 1_555 B C 97  1_555 B G 143 1_555 B C 96  1_555 -1.682 -3.686 -1.713 113.097 -124.762 -19.545  0.729   -1.863 -1.870 
65.948  59.782  -168.563 49 BB_G142G143:C96C97_BB   B 142 ? B 97  ? B 143 ? B 96  ? 
1 B G 143 1_555 B C 96  1_555 B A 144 1_555 B U 95  1_555 -0.119 -1.674 3.382  -0.917  4.304    33.456   -3.585  0.055  3.151  
7.437   1.584   33.735   50 BB_G143A144:U95C96_BB   B 143 ? B 96  ? B 144 ? B 95  ? 
1 B A 144 1_555 B U 95  1_555 B C 145 1_555 B G 94  1_555 0.415  -1.578 3.265  2.663   1.204    31.588   -3.107  -0.272 3.227  
2.205   -4.878  31.719   51 BB_A144C145:G94U95_BB   B 144 ? B 95  ? B 145 ? B 94  ? 
# 
_pdbx_audit_support.funding_organization   'Welch Foundation' 
_pdbx_audit_support.country                'United States' 
_pdbx_audit_support.grant_number           F-1938 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    8W2S 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
P 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM 1    N N     . ILE A 1 43  ? 128.708 149.436 134.742 1.00 69.68  ? 43  ILE A N     1 
ATOM 2    C CA    . ILE A 1 43  ? 127.952 148.228 135.039 1.00 70.96  ? 43  ILE A CA    1 
ATOM 3    C C     . ILE A 1 43  ? 128.909 147.034 134.992 1.00 65.86  ? 43  ILE A C     1 
ATOM 4    O O     . ILE A 1 43  ? 129.673 146.869 134.041 1.00 64.24  ? 43  ILE A O     1 
ATOM 5    C CB    . ILE A 1 43  ? 126.756 148.065 134.066 1.00 68.68  ? 43  ILE A CB    1 
ATOM 6    C CG1   . ILE A 1 43  ? 126.107 146.684 134.197 1.00 61.96  ? 43  ILE A CG1   1 
ATOM 7    C CG2   . ILE A 1 43  ? 127.174 148.355 132.627 1.00 68.29  ? 43  ILE A CG2   1 
ATOM 8    C CD1   . ILE A 1 43  ? 125.518 146.411 135.570 1.00 63.50  ? 43  ILE A CD1   1 
ATOM 9    N N     . LEU A 1 44  ? 128.877 146.212 136.040 1.00 61.47  ? 44  LEU A N     1 
ATOM 10   C CA    . LEU A 1 44  ? 129.793 145.089 136.184 1.00 57.44  ? 44  LEU A CA    1 
ATOM 11   C C     . LEU A 1 44  ? 129.120 143.743 135.951 1.00 56.62  ? 44  LEU A C     1 
ATOM 12   O O     . LEU A 1 44  ? 129.724 142.705 136.242 1.00 55.77  ? 44  LEU A O     1 
ATOM 13   C CB    . LEU A 1 44  ? 130.459 145.095 137.566 1.00 58.07  ? 44  LEU A CB    1 
ATOM 14   C CG    . LEU A 1 44  ? 131.419 146.189 138.057 1.00 62.58  ? 44  LEU A CG    1 
ATOM 15   C CD1   . LEU A 1 44  ? 131.838 146.047 139.520 1.00 67.58  ? 44  LEU A CD1   1 
ATOM 16   C CD2   . LEU A 1 44  ? 132.646 146.232 137.160 1.00 61.51  ? 44  LEU A CD2   1 
ATOM 17   N N     . LYS A 1 45  ? 127.881 143.733 135.451 1.00 59.46  ? 45  LYS A N     1 
ATOM 18   C CA    . LYS A 1 45  ? 127.181 142.472 135.220 1.00 58.97  ? 45  LYS A CA    1 
ATOM 19   C C     . LYS A 1 45  ? 127.836 141.668 134.103 1.00 57.91  ? 45  LYS A C     1 
ATOM 20   O O     . LYS A 1 45  ? 127.980 140.443 134.211 1.00 59.86  ? 45  LYS A O     1 
ATOM 21   C CB    . LYS A 1 45  ? 125.713 142.746 134.901 1.00 63.12  ? 45  LYS A CB    1 
ATOM 22   C CG    . LYS A 1 45  ? 124.826 141.516 134.900 1.00 67.89  ? 45  LYS A CG    1 
ATOM 23   C CD    . LYS A 1 45  ? 123.365 141.910 134.755 1.00 74.32  ? 45  LYS A CD    1 
ATOM 24   C CE    . LYS A 1 45  ? 122.874 142.650 135.990 1.00 71.42  ? 45  LYS A CE    1 
ATOM 25   N NZ    . LYS A 1 45  ? 121.430 142.997 135.898 1.00 71.90  ? 45  LYS A NZ    1 
ATOM 26   N N     . ASP A 1 46  ? 128.245 142.340 133.025 1.00 56.57  ? 46  ASP A N     1 
ATOM 27   C CA    . ASP A 1 46  ? 128.984 141.663 131.966 1.00 54.60  ? 46  ASP A CA    1 
ATOM 28   C C     . ASP A 1 46  ? 130.357 141.212 132.443 1.00 52.11  ? 46  ASP A C     1 
ATOM 29   O O     . ASP A 1 46  ? 130.853 140.168 132.001 1.00 49.71  ? 46  ASP A O     1 
ATOM 30   C CB    . ASP A 1 46  ? 129.105 142.577 130.748 1.00 59.76  ? 46  ASP A CB    1 
ATOM 31   C CG    . ASP A 1 46  ? 129.655 143.943 131.099 1.00 63.44  ? 46  ASP A CG    1 
ATOM 32   O OD1   . ASP A 1 46  ? 129.730 144.265 132.304 1.00 60.51  ? 46  ASP A OD1   1 
ATOM 33   O OD2   . ASP A 1 46  ? 130.005 144.698 130.169 1.00 68.17  ? 46  ASP A OD2   1 
ATOM 34   N N     . ARG A 1 47  ? 130.975 141.975 133.350 1.00 52.76  ? 47  ARG A N     1 
ATOM 35   C CA    . ARG A 1 47  ? 132.218 141.527 133.969 1.00 47.75  ? 47  ARG A CA    1 
ATOM 36   C C     . ARG A 1 47  ? 132.000 140.260 134.781 1.00 46.92  ? 47  ARG A C     1 
ATOM 37   O O     . ARG A 1 47  ? 132.836 139.353 134.755 1.00 47.67  ? 47  ARG A O     1 
ATOM 38   C CB    . ARG A 1 47  ? 132.806 142.625 134.852 1.00 46.64  ? 47  ARG A CB    1 
ATOM 39   C CG    . ARG A 1 47  ? 134.275 142.405 135.169 1.00 48.79  ? 47  ARG A CG    1 
ATOM 40   C CD    . ARG A 1 47  ? 134.887 143.584 135.897 1.00 52.06  ? 47  ARG A CD    1 
ATOM 41   N NE    . ARG A 1 47  ? 134.587 143.573 137.322 1.00 48.86  ? 47  ARG A NE    1 
ATOM 42   C CZ    . ARG A 1 47  ? 135.479 143.315 138.267 1.00 41.97  ? 47  ARG A CZ    1 
ATOM 43   N NH1   . ARG A 1 47  ? 136.738 143.040 137.972 1.00 40.58  ? 47  ARG A NH1   1 
ATOM 44   N NH2   . ARG A 1 47  ? 135.099 143.335 139.541 1.00 42.00  ? 47  ARG A NH2   1 
ATOM 45   N N     . ARG A 1 48  ? 130.879 140.179 135.504 1.00 46.86  ? 48  ARG A N     1 
ATOM 46   C CA    . ARG A 1 48  ? 130.569 138.977 136.273 1.00 43.84  ? 48  ARG A CA    1 
ATOM 47   C C     . ARG A 1 48  ? 130.331 137.791 135.340 1.00 43.70  ? 48  ARG A C     1 
ATOM 48   O O     . ARG A 1 48  ? 130.773 136.672 135.624 1.00 45.36  ? 48  ARG A O     1 
ATOM 49   C CB    . ARG A 1 48  ? 129.349 139.242 137.165 1.00 46.13  ? 48  ARG A CB    1 
ATOM 50   C CG    . ARG A 1 48  ? 128.628 138.028 137.789 1.00 45.18  ? 48  ARG A CG    1 
ATOM 51   C CD    . ARG A 1 48  ? 129.562 137.063 138.539 1.00 46.77  ? 48  ARG A CD    1 
ATOM 52   N NE    . ARG A 1 48  ? 129.089 135.683 138.490 1.00 48.93  ? 48  ARG A NE    1 
ATOM 53   C CZ    . ARG A 1 48  ? 129.790 134.634 138.897 1.00 43.57  ? 48  ARG A CZ    1 
ATOM 54   N NH1   . ARG A 1 48  ? 131.002 134.768 139.407 1.00 35.64  ? 48  ARG A NH1   1 
ATOM 55   N NH2   . ARG A 1 48  ? 129.261 133.419 138.791 1.00 45.88  ? 48  ARG A NH2   1 
ATOM 56   N N     . LYS A 1 49  ? 129.645 138.022 134.217 1.00 43.82  ? 49  LYS A N     1 
ATOM 57   C CA    . LYS A 1 49  ? 129.404 136.949 133.254 1.00 41.24  ? 49  LYS A CA    1 
ATOM 58   C C     . LYS A 1 49  ? 130.707 136.436 132.647 1.00 41.40  ? 49  LYS A C     1 
ATOM 59   O O     . LYS A 1 49  ? 130.916 135.218 132.538 1.00 42.59  ? 49  LYS A O     1 
ATOM 60   C CB    . LYS A 1 49  ? 128.458 137.444 132.162 1.00 43.29  ? 49  LYS A CB    1 
ATOM 61   C CG    . LYS A 1 49  ? 128.237 136.467 131.027 1.00 47.57  ? 49  LYS A CG    1 
ATOM 62   C CD    . LYS A 1 49  ? 127.540 137.139 129.855 1.00 48.99  ? 49  LYS A CD    1 
ATOM 63   C CE    . LYS A 1 49  ? 128.463 138.113 129.140 1.00 49.29  ? 49  LYS A CE    1 
ATOM 64   N NZ    . LYS A 1 49  ? 129.174 137.472 127.999 1.00 52.46  ? 49  LYS A NZ    1 
ATOM 65   N N     . GLN A 1 50  ? 131.605 137.349 132.270 1.00 43.22  ? 50  GLN A N     1 
ATOM 66   C CA    . GLN A 1 50  ? 132.898 136.938 131.732 1.00 39.20  ? 50  GLN A CA    1 
ATOM 67   C C     . GLN A 1 50  ? 133.742 136.246 132.794 1.00 38.05  ? 50  GLN A C     1 
ATOM 68   O O     . GLN A 1 50  ? 134.472 135.296 132.491 1.00 38.45  ? 50  GLN A O     1 
ATOM 69   C CB    . GLN A 1 50  ? 133.636 138.145 131.157 1.00 39.18  ? 50  GLN A CB    1 
ATOM 70   C CG    . GLN A 1 50  ? 134.910 137.789 130.425 1.00 35.63  ? 50  GLN A CG    1 
ATOM 71   C CD    . GLN A 1 50  ? 134.679 136.800 129.306 1.00 39.73  ? 50  GLN A CD    1 
ATOM 72   O OE1   . GLN A 1 50  ? 133.739 136.937 128.526 1.00 50.89  ? 50  GLN A OE1   1 
ATOM 73   N NE2   . GLN A 1 50  ? 135.538 135.793 129.222 1.00 35.96  ? 50  GLN A NE2   1 
ATOM 74   N N     . ARG A 1 51  ? 133.636 136.702 134.045 1.00 37.36  ? 51  ARG A N     1 
ATOM 75   C CA    . ARG A 1 51  ? 134.306 136.048 135.162 1.00 34.79  ? 51  ARG A CA    1 
ATOM 76   C C     . ARG A 1 51  ? 133.836 134.610 135.319 1.00 32.18  ? 51  ARG A C     1 
ATOM 77   O O     . ARG A 1 51  ? 134.648 133.696 135.510 1.00 32.73  ? 51  ARG A O     1 
ATOM 78   C CB    . ARG A 1 51  ? 134.025 136.832 136.443 1.00 34.26  ? 51  ARG A CB    1 
ATOM 79   C CG    . ARG A 1 51  ? 134.986 136.590 137.574 1.00 30.00  ? 51  ARG A CG    1 
ATOM 80   C CD    . ARG A 1 51  ? 134.326 136.922 138.904 1.00 30.63  ? 51  ARG A CD    1 
ATOM 81   N NE    . ARG A 1 51  ? 133.636 138.206 138.919 1.00 34.60  ? 51  ARG A NE    1 
ATOM 82   C CZ    . ARG A 1 51  ? 134.232 139.387 138.971 1.00 39.28  ? 51  ARG A CZ    1 
ATOM 83   N NH1   . ARG A 1 51  ? 135.548 139.498 139.029 1.00 35.78  ? 51  ARG A NH1   1 
ATOM 84   N NH2   . ARG A 1 51  ? 133.487 140.487 138.985 1.00 47.42  ? 51  ARG A NH2   1 
ATOM 85   N N     . GLY A 1 52  ? 132.523 134.397 135.232 1.00 33.31  ? 52  GLY A N     1 
ATOM 86   C CA    . GLY A 1 52  ? 131.984 133.056 135.364 1.00 34.99  ? 52  GLY A CA    1 
ATOM 87   C C     . GLY A 1 52  ? 132.407 132.144 134.231 1.00 34.95  ? 52  GLY A C     1 
ATOM 88   O O     . GLY A 1 52  ? 132.750 130.982 134.461 1.00 39.66  ? 52  GLY A O     1 
ATOM 89   N N     . ILE A 1 53  ? 132.406 132.664 132.998 1.00 32.67  ? 53  ILE A N     1 
ATOM 90   C CA    . ILE A 1 53  ? 132.854 131.868 131.854 1.00 31.60  ? 53  ILE A CA    1 
ATOM 91   C C     . ILE A 1 53  ? 134.327 131.501 131.999 1.00 33.99  ? 53  ILE A C     1 
ATOM 92   O O     . ILE A 1 53  ? 134.722 130.346 131.775 1.00 34.18  ? 53  ILE A O     1 
ATOM 93   C CB    . ILE A 1 53  ? 132.585 132.624 130.541 1.00 30.62  ? 53  ILE A CB    1 
ATOM 94   C CG1   . ILE A 1 53  ? 131.087 132.826 130.339 1.00 30.85  ? 53  ILE A CG1   1 
ATOM 95   C CG2   . ILE A 1 53  ? 133.161 131.869 129.362 1.00 30.30  ? 53  ILE A CG2   1 
ATOM 96   C CD1   . ILE A 1 53  ? 130.755 133.888 129.323 1.00 35.85  ? 53  ILE A CD1   1 
ATOM 97   N N     . ARG A 1 54  ? 135.150 132.470 132.412 1.00 35.86  ? 54  ARG A N     1 
ATOM 98   C CA    . ARG A 1 54  ? 136.580 132.245 132.601 1.00 30.15  ? 54  ARG A CA    1 
ATOM 99   C C     . ARG A 1 54  ? 136.846 131.182 133.658 1.00 29.96  ? 54  ARG A C     1 
ATOM 100  O O     . ARG A 1 54  ? 137.623 130.246 133.434 1.00 32.24  ? 54  ARG A O     1 
ATOM 101  C CB    . ARG A 1 54  ? 137.242 133.562 132.994 1.00 25.95  ? 54  ARG A CB    1 
ATOM 102  C CG    . ARG A 1 54  ? 138.699 133.464 133.362 1.00 26.13  ? 54  ARG A CG    1 
ATOM 103  C CD    . ARG A 1 54  ? 139.290 134.852 133.437 1.00 29.22  ? 54  ARG A CD    1 
ATOM 104  N NE    . ARG A 1 54  ? 138.781 135.580 134.591 1.00 24.82  ? 54  ARG A NE    1 
ATOM 105  C CZ    . ARG A 1 54  ? 138.341 136.829 134.549 1.00 29.26  ? 54  ARG A CZ    1 
ATOM 106  N NH1   . ARG A 1 54  ? 138.328 137.518 133.422 1.00 35.76  ? 54  ARG A NH1   1 
ATOM 107  N NH2   . ARG A 1 54  ? 137.899 137.398 135.665 1.00 32.30  ? 54  ARG A NH2   1 
ATOM 108  N N     . ARG A 1 55  ? 136.188 131.298 134.811 1.00 29.40  ? 55  ARG A N     1 
ATOM 109  C CA    . ARG A 1 55  ? 136.453 130.367 135.900 1.00 29.70  ? 55  ARG A CA    1 
ATOM 110  C C     . ARG A 1 55  ? 135.888 128.982 135.612 1.00 32.43  ? 55  ARG A C     1 
ATOM 111  O O     . ARG A 1 55  ? 136.495 127.979 136.004 1.00 36.72  ? 55  ARG A O     1 
ATOM 112  C CB    . ARG A 1 55  ? 135.902 130.936 137.203 1.00 24.40  ? 55  ARG A CB    1 
ATOM 113  C CG    . ARG A 1 55  ? 136.666 132.169 137.647 1.00 22.20  ? 55  ARG A CG    1 
ATOM 114  C CD    . ARG A 1 55  ? 136.079 132.816 138.877 1.00 25.69  ? 55  ARG A CD    1 
ATOM 115  N NE    . ARG A 1 55  ? 136.829 134.008 139.251 1.00 26.26  ? 55  ARG A NE    1 
ATOM 116  C CZ    . ARG A 1 55  ? 136.604 134.723 140.342 1.00 27.23  ? 55  ARG A CZ    1 
ATOM 117  N NH1   . ARG A 1 55  ? 135.646 134.402 141.193 1.00 27.11  ? 55  ARG A NH1   1 
ATOM 118  N NH2   . ARG A 1 55  ? 137.356 135.790 140.583 1.00 27.67  ? 55  ARG A NH2   1 
ATOM 119  N N     . THR A 1 56  ? 134.755 128.902 134.907 1.00 31.47  ? 56  THR A N     1 
ATOM 120  C CA    . THR A 1 56  ? 134.226 127.608 134.490 1.00 29.32  ? 56  THR A CA    1 
ATOM 121  C C     . THR A 1 56  ? 135.168 126.911 133.516 1.00 29.73  ? 56  THR A C     1 
ATOM 122  O O     . THR A 1 56  ? 135.419 125.703 133.639 1.00 31.40  ? 56  THR A O     1 
ATOM 123  C CB    . THR A 1 56  ? 132.847 127.801 133.864 1.00 28.38  ? 56  THR A CB    1 
ATOM 124  O OG1   . THR A 1 56  ? 131.966 128.391 134.827 1.00 32.07  ? 56  THR A OG1   1 
ATOM 125  C CG2   . THR A 1 56  ? 132.275 126.482 133.417 1.00 30.29  ? 56  THR A CG2   1 
ATOM 126  N N     . ALA A 1 57  ? 135.716 127.661 132.552 1.00 31.28  ? 57  ALA A N     1 
ATOM 127  C CA    . ALA A 1 57  ? 136.674 127.080 131.616 1.00 29.42  ? 57  ALA A CA    1 
ATOM 128  C C     . ALA A 1 57  ? 137.944 126.632 132.327 1.00 31.51  ? 57  ALA A C     1 
ATOM 129  O O     . ALA A 1 57  ? 138.502 125.574 132.010 1.00 30.95  ? 57  ALA A O     1 
ATOM 130  C CB    . ALA A 1 57  ? 137.002 128.083 130.513 1.00 26.36  ? 57  ALA A CB    1 
ATOM 131  N N     . GLN A 1 58  ? 138.410 127.419 133.302 1.00 31.61  ? 58  GLN A N     1 
ATOM 132  C CA    . GLN A 1 58  ? 139.594 127.032 134.062 1.00 29.17  ? 58  GLN A CA    1 
ATOM 133  C C     . GLN A 1 58  ? 139.351 125.762 134.868 1.00 33.84  ? 58  GLN A C     1 
ATOM 134  O O     . GLN A 1 58  ? 140.217 124.883 134.923 1.00 39.51  ? 58  GLN A O     1 
ATOM 135  C CB    . GLN A 1 58  ? 140.030 128.172 134.980 1.00 26.22  ? 58  GLN A CB    1 
ATOM 136  C CG    . GLN A 1 58  ? 140.674 129.336 134.253 1.00 26.97  ? 58  GLN A CG    1 
ATOM 137  C CD    . GLN A 1 58  ? 141.013 130.483 135.178 1.00 29.31  ? 58  GLN A CD    1 
ATOM 138  O OE1   . GLN A 1 58  ? 140.791 130.408 136.385 1.00 30.61  ? 58  GLN A OE1   1 
ATOM 139  N NE2   . GLN A 1 58  ? 141.552 131.556 134.615 1.00 24.65  ? 58  GLN A NE2   1 
ATOM 140  N N     . THR A 1 59  ? 138.174 125.643 135.491 1.00 31.17  ? 59  THR A N     1 
ATOM 141  C CA    . THR A 1 59  ? 137.856 124.443 136.261 1.00 29.97  ? 59  THR A CA    1 
ATOM 142  C C     . THR A 1 59  ? 137.757 123.213 135.363 1.00 31.47  ? 59  THR A C     1 
ATOM 143  O O     . THR A 1 59  ? 138.225 122.122 135.730 1.00 35.60  ? 59  THR A O     1 
ATOM 144  C CB    . THR A 1 59  ? 136.557 124.659 137.031 1.00 29.96  ? 59  THR A CB    1 
ATOM 145  O OG1   . THR A 1 59  ? 136.764 125.652 138.040 1.00 31.92  ? 59  THR A OG1   1 
ATOM 146  C CG2   . THR A 1 59  ? 136.113 123.381 137.700 1.00 32.05  ? 59  THR A CG2   1 
ATOM 147  N N     . LYS A 1 60  ? 137.167 123.374 134.173 1.00 31.36  ? 60  LYS A N     1 
ATOM 148  C CA    . LYS A 1 60  ? 137.145 122.278 133.209 1.00 32.68  ? 60  LYS A CA    1 
ATOM 149  C C     . LYS A 1 60  ? 138.554 121.874 132.797 1.00 34.17  ? 60  LYS A C     1 
ATOM 150  O O     . LYS A 1 60  ? 138.845 120.681 132.657 1.00 35.96  ? 60  LYS A O     1 
ATOM 151  C CB    . LYS A 1 60  ? 136.319 122.657 131.984 1.00 28.23  ? 60  LYS A CB    1 
ATOM 152  C CG    . LYS A 1 60  ? 135.922 121.462 131.140 1.00 25.45  ? 60  LYS A CG    1 
ATOM 153  C CD    . LYS A 1 60  ? 135.086 121.876 129.950 1.00 30.90  ? 60  LYS A CD    1 
ATOM 154  C CE    . LYS A 1 60  ? 133.790 122.514 130.398 1.00 31.49  ? 60  LYS A CE    1 
ATOM 155  N NZ    . LYS A 1 60  ? 132.894 121.506 131.024 1.00 30.21  ? 60  LYS A NZ    1 
ATOM 156  N N     . LYS A 1 61  ? 139.444 122.856 132.613 1.00 34.00  ? 61  LYS A N     1 
ATOM 157  C CA    . LYS A 1 61  ? 140.847 122.556 132.334 1.00 32.75  ? 61  LYS A CA    1 
ATOM 158  C C     . LYS A 1 61  ? 141.480 121.748 133.457 1.00 38.24  ? 61  LYS A C     1 
ATOM 159  O O     . LYS A 1 61  ? 142.205 120.779 133.199 1.00 44.95  ? 61  LYS A O     1 
ATOM 160  C CB    . LYS A 1 61  ? 141.630 123.848 132.129 1.00 33.51  ? 61  LYS A CB    1 
ATOM 161  C CG    . LYS A 1 61  ? 141.581 124.419 130.737 1.00 36.29  ? 61  LYS A CG    1 
ATOM 162  C CD    . LYS A 1 61  ? 142.186 125.804 130.734 1.00 37.71  ? 61  LYS A CD    1 
ATOM 163  C CE    . LYS A 1 61  ? 142.813 126.122 129.403 1.00 46.10  ? 61  LYS A CE    1 
ATOM 164  N NZ    . LYS A 1 61  ? 144.172 125.527 129.308 1.00 58.17  ? 61  LYS A NZ    1 
ATOM 165  N N     . LYS A 1 62  ? 141.211 122.134 134.710 1.00 36.03  ? 62  LYS A N     1 
ATOM 166  C CA    . LYS A 1 62  ? 141.776 121.419 135.852 1.00 36.22  ? 62  LYS A CA    1 
ATOM 167  C C     . LYS A 1 62  ? 141.303 119.973 135.898 1.00 37.86  ? 62  LYS A C     1 
ATOM 168  O O     . LYS A 1 62  ? 142.110 119.056 136.104 1.00 43.17  ? 62  LYS A O     1 
ATOM 169  C CB    . LYS A 1 62  ? 141.422 122.124 137.162 1.00 35.81  ? 62  LYS A CB    1 
ATOM 170  C CG    . LYS A 1 62  ? 141.868 123.564 137.261 1.00 38.16  ? 62  LYS A CG    1 
ATOM 171  C CD    . LYS A 1 62  ? 141.961 124.021 138.704 1.00 37.81  ? 62  LYS A CD    1 
ATOM 172  C CE    . LYS A 1 62  ? 141.644 125.499 138.826 1.00 36.79  ? 62  LYS A CE    1 
ATOM 173  N NZ    . LYS A 1 62  ? 141.093 125.842 140.160 1.00 32.29  ? 62  LYS A NZ    1 
ATOM 174  N N     . ARG A 1 63  ? 140.006 119.740 135.689 1.00 36.76  ? 63  ARG A N     1 
ATOM 175  C CA    . ARG A 1 63  ? 139.538 118.363 135.812 1.00 35.27  ? 63  ARG A CA    1 
ATOM 176  C C     . ARG A 1 63  ? 139.930 117.512 134.615 1.00 36.92  ? 63  ARG A C     1 
ATOM 177  O O     . ARG A 1 63  ? 140.183 116.314 134.782 1.00 41.75  ? 63  ARG A O     1 
ATOM 178  C CB    . ARG A 1 63  ? 138.028 118.293 136.035 1.00 30.97  ? 63  ARG A CB    1 
ATOM 179  C CG    . ARG A 1 63  ? 137.159 118.929 134.986 1.00 32.77  ? 63  ARG A CG    1 
ATOM 180  C CD    . ARG A 1 63  ? 135.740 118.372 135.073 1.00 31.04  ? 63  ARG A CD    1 
ATOM 181  N NE    . ARG A 1 63  ? 135.306 118.077 136.436 1.00 31.32  ? 63  ARG A NE    1 
ATOM 182  C CZ    . ARG A 1 63  ? 134.956 118.985 137.338 1.00 34.09  ? 63  ARG A CZ    1 
ATOM 183  N NH1   . ARG A 1 63  ? 134.940 120.275 137.054 1.00 36.32  ? 63  ARG A NH1   1 
ATOM 184  N NH2   . ARG A 1 63  ? 134.606 118.586 138.556 1.00 34.80  ? 63  ARG A NH2   1 
ATOM 185  N N     . LEU A 1 64  ? 140.025 118.096 133.417 1.00 36.17  ? 64  LEU A N     1 
ATOM 186  C CA    . LEU A 1 64  ? 140.546 117.330 132.291 1.00 37.29  ? 64  LEU A CA    1 
ATOM 187  C C     . LEU A 1 64  ? 142.016 116.988 132.488 1.00 44.54  ? 64  LEU A C     1 
ATOM 188  O O     . LEU A 1 64  ? 142.444 115.882 132.145 1.00 48.56  ? 64  LEU A O     1 
ATOM 189  C CB    . LEU A 1 64  ? 140.333 118.080 130.981 1.00 31.97  ? 64  LEU A CB    1 
ATOM 190  C CG    . LEU A 1 64  ? 138.867 118.231 130.598 1.00 29.42  ? 64  LEU A CG    1 
ATOM 191  C CD1   . LEU A 1 64  ? 138.711 119.161 129.416 1.00 34.88  ? 64  LEU A CD1   1 
ATOM 192  C CD2   . LEU A 1 64  ? 138.297 116.872 130.294 1.00 39.11  ? 64  LEU A CD2   1 
ATOM 193  N N     . ARG A 1 65  ? 142.797 117.908 133.063 1.00 44.80  ? 65  ARG A N     1 
ATOM 194  C CA    . ARG A 1 65  ? 144.195 117.605 133.351 1.00 45.43  ? 65  ARG A CA    1 
ATOM 195  C C     . ARG A 1 65  ? 144.326 116.497 134.388 1.00 47.83  ? 65  ARG A C     1 
ATOM 196  O O     . ARG A 1 65  ? 145.166 115.601 134.242 1.00 54.10  ? 65  ARG A O     1 
ATOM 197  C CB    . ARG A 1 65  ? 144.922 118.859 133.827 1.00 48.24  ? 65  ARG A CB    1 
ATOM 198  C CG    . ARG A 1 65  ? 146.431 118.730 133.800 1.00 53.76  ? 65  ARG A CG    1 
ATOM 199  C CD    . ARG A 1 65  ? 147.077 119.825 134.618 1.00 58.57  ? 65  ARG A CD    1 
ATOM 200  N NE    . ARG A 1 65  ? 146.700 121.147 134.135 1.00 65.23  ? 65  ARG A NE    1 
ATOM 201  C CZ    . ARG A 1 65  ? 146.170 122.094 134.894 1.00 66.48  ? 65  ARG A CZ    1 
ATOM 202  N NH1   . ARG A 1 65  ? 145.926 121.893 136.178 1.00 66.78  ? 65  ARG A NH1   1 
ATOM 203  N NH2   . ARG A 1 65  ? 145.873 123.270 134.350 1.00 62.84  ? 65  ARG A NH2   1 
ATOM 204  N N     . GLU A 1 66  ? 143.503 116.537 135.440 1.00 45.35  ? 66  GLU A N     1 
ATOM 205  C CA    . GLU A 1 66  ? 143.577 115.496 136.462 1.00 46.74  ? 66  GLU A CA    1 
ATOM 206  C C     . GLU A 1 66  ? 143.131 114.143 135.924 1.00 47.90  ? 66  GLU A C     1 
ATOM 207  O O     . GLU A 1 66  ? 143.745 113.116 136.239 1.00 51.94  ? 66  GLU A O     1 
ATOM 208  C CB    . GLU A 1 66  ? 142.754 115.885 137.686 1.00 43.39  ? 66  GLU A CB    1 
ATOM 209  C CG    . GLU A 1 66  ? 143.600 116.433 138.815 1.00 46.47  ? 66  GLU A CG    1 
ATOM 210  C CD    . GLU A 1 66  ? 142.778 116.921 139.982 1.00 54.36  ? 66  GLU A CD    1 
ATOM 211  O OE1   . GLU A 1 66  ? 141.865 116.191 140.419 1.00 48.10  ? 66  GLU A OE1   1 
ATOM 212  O OE2   . GLU A 1 66  ? 143.052 118.035 140.470 1.00 67.77  ? 66  GLU A OE2   1 
ATOM 213  N N     . LEU A 1 67  ? 142.078 114.118 135.103 1.00 45.81  ? 67  LEU A N     1 
ATOM 214  C CA    . LEU A 1 67  ? 141.642 112.853 134.522 1.00 46.21  ? 67  LEU A CA    1 
ATOM 215  C C     . LEU A 1 67  ? 142.678 112.307 133.547 1.00 51.84  ? 67  LEU A C     1 
ATOM 216  O O     . LEU A 1 67  ? 142.932 111.096 133.520 1.00 56.61  ? 67  LEU A O     1 
ATOM 217  C CB    . LEU A 1 67  ? 140.290 113.024 133.835 1.00 38.44  ? 67  LEU A CB    1 
ATOM 218  C CG    . LEU A 1 67  ? 139.733 111.724 133.264 1.00 34.96  ? 67  LEU A CG    1 
ATOM 219  C CD1   . LEU A 1 67  ? 139.463 110.723 134.367 1.00 40.80  ? 67  LEU A CD1   1 
ATOM 220  C CD2   . LEU A 1 67  ? 138.484 111.980 132.477 1.00 43.49  ? 67  LEU A CD2   1 
ATOM 221  N N     . LYS A 1 68  ? 143.301 113.189 132.759 1.00 51.30  ? 68  LYS A N     1 
ATOM 222  C CA    . LYS A 1 68  ? 144.367 112.779 131.852 1.00 52.69  ? 68  LYS A CA    1 
ATOM 223  C C     . LYS A 1 68  ? 145.538 112.182 132.617 1.00 56.05  ? 68  LYS A C     1 
ATOM 224  O O     . LYS A 1 68  ? 146.040 111.109 132.265 1.00 60.65  ? 68  LYS A O     1 
ATOM 225  C CB    . LYS A 1 68  ? 144.823 113.981 131.027 1.00 49.77  ? 68  LYS A CB    1 
ATOM 226  C CG    . LYS A 1 68  ? 145.682 113.652 129.827 1.00 49.77  ? 68  LYS A CG    1 
ATOM 227  C CD    . LYS A 1 68  ? 145.869 114.890 128.967 1.00 49.84  ? 68  LYS A CD    1 
ATOM 228  C CE    . LYS A 1 68  ? 146.530 114.559 127.644 1.00 52.81  ? 68  LYS A CE    1 
ATOM 229  N NZ    . LYS A 1 68  ? 146.563 115.744 126.743 1.00 50.83  ? 68  LYS A NZ    1 
ATOM 230  N N     . ASN A 1 69  ? 145.962 112.853 133.693 1.00 53.31  ? 69  ASN A N     1 
ATOM 231  C CA    . ASN A 1 69  ? 147.080 112.363 134.492 1.00 54.57  ? 69  ASN A CA    1 
ATOM 232  C C     . ASN A 1 69  ? 146.756 111.029 135.149 1.00 57.33  ? 69  ASN A C     1 
ATOM 233  O O     . ASN A 1 69  ? 147.600 110.127 135.179 1.00 60.83  ? 69  ASN A O     1 
ATOM 234  C CB    . ASN A 1 69  ? 147.465 113.398 135.547 1.00 50.78  ? 69  ASN A CB    1 
ATOM 235  C CG    . ASN A 1 69  ? 148.111 114.625 134.947 1.00 50.00  ? 69  ASN A CG    1 
ATOM 236  O OD1   . ASN A 1 69  ? 148.529 114.617 133.791 1.00 51.52  ? 69  ASN A OD1   1 
ATOM 237  N ND2   . ASN A 1 69  ? 148.194 115.693 135.731 1.00 50.77  ? 69  ASN A ND2   1 
ATOM 238  N N     . TYR A 1 70  ? 145.531 110.868 135.656 1.00 55.65  ? 70  TYR A N     1 
ATOM 239  C CA    . TYR A 1 70  ? 145.204 109.628 136.349 1.00 58.40  ? 70  TYR A CA    1 
ATOM 240  C C     . TYR A 1 70  ? 145.065 108.461 135.375 1.00 63.05  ? 70  TYR A C     1 
ATOM 241  O O     . TYR A 1 70  ? 145.520 107.347 135.667 1.00 66.74  ? 70  TYR A O     1 
ATOM 242  C CB    . TYR A 1 70  ? 143.929 109.792 137.170 1.00 57.84  ? 70  TYR A CB    1 
ATOM 243  C CG    . TYR A 1 70  ? 143.482 108.495 137.792 1.00 63.95  ? 70  TYR A CG    1 
ATOM 244  C CD1   . TYR A 1 70  ? 144.308 107.816 138.677 1.00 65.22  ? 70  TYR A CD1   1 
ATOM 245  C CD2   . TYR A 1 70  ? 142.247 107.942 137.493 1.00 65.08  ? 70  TYR A CD2   1 
ATOM 246  C CE1   . TYR A 1 70  ? 143.917 106.628 139.248 1.00 68.15  ? 70  TYR A CE1   1 
ATOM 247  C CE2   . TYR A 1 70  ? 141.844 106.753 138.064 1.00 68.87  ? 70  TYR A CE2   1 
ATOM 248  C CZ    . TYR A 1 70  ? 142.687 106.099 138.935 1.00 73.64  ? 70  TYR A CZ    1 
ATOM 249  O OH    . TYR A 1 70  ? 142.297 104.916 139.511 1.00 80.80  ? 70  TYR A OH    1 
ATOM 250  N N     . LEU A 1 71  ? 144.445 108.689 134.212 1.00 59.85  ? 71  LEU A N     1 
ATOM 251  C CA    . LEU A 1 71  ? 144.342 107.616 133.229 1.00 59.50  ? 71  LEU A CA    1 
ATOM 252  C C     . LEU A 1 71  ? 145.696 107.276 132.619 1.00 65.88  ? 71  LEU A C     1 
ATOM 253  O O     . LEU A 1 71  ? 145.920 106.125 132.230 1.00 73.30  ? 71  LEU A O     1 
ATOM 254  C CB    . LEU A 1 71  ? 143.339 107.982 132.137 1.00 54.45  ? 71  LEU A CB    1 
ATOM 255  C CG    . LEU A 1 71  ? 141.880 108.139 132.565 1.00 51.14  ? 71  LEU A CG    1 
ATOM 256  C CD1   . LEU A 1 71  ? 141.080 108.782 131.459 1.00 55.83  ? 71  LEU A CD1   1 
ATOM 257  C CD2   . LEU A 1 71  ? 141.285 106.795 132.927 1.00 57.43  ? 71  LEU A CD2   1 
ATOM 258  N N     . LYS A 1 72  ? 146.608 108.248 132.523 1.00 63.70  ? 72  LYS A N     1 
ATOM 259  C CA    . LYS A 1 72  ? 147.979 107.919 132.150 1.00 66.47  ? 72  LYS A CA    1 
ATOM 260  C C     . LYS A 1 72  ? 148.663 107.104 133.240 1.00 68.21  ? 72  LYS A C     1 
ATOM 261  O O     . LYS A 1 72  ? 149.429 106.180 132.944 1.00 71.40  ? 72  LYS A O     1 
ATOM 262  C CB    . LYS A 1 72  ? 148.767 109.195 131.858 1.00 65.73  ? 72  LYS A CB    1 
ATOM 263  C CG    . LYS A 1 72  ? 148.427 109.857 130.534 1.00 64.47  ? 72  LYS A CG    1 
ATOM 264  C CD    . LYS A 1 72  ? 149.249 111.116 130.332 1.00 60.77  ? 72  LYS A CD    1 
ATOM 265  C CE    . LYS A 1 72  ? 149.045 111.695 128.947 1.00 62.76  ? 72  LYS A CE    1 
ATOM 266  N NZ    . LYS A 1 72  ? 150.003 112.798 128.675 1.00 58.77  ? 72  LYS A NZ    1 
ATOM 267  N N     . SER A 1 73  ? 148.398 107.434 134.507 1.00 68.08  ? 73  SER A N     1 
ATOM 268  C CA    . SER A 1 73  ? 149.003 106.716 135.621 1.00 69.21  ? 73  SER A CA    1 
ATOM 269  C C     . SER A 1 73  ? 148.467 105.300 135.772 1.00 70.68  ? 73  SER A C     1 
ATOM 270  O O     . SER A 1 73  ? 149.140 104.464 136.382 1.00 72.29  ? 73  SER A O     1 
ATOM 271  C CB    . SER A 1 73  ? 148.786 107.488 136.922 1.00 68.89  ? 73  SER A CB    1 
ATOM 272  O OG    . SER A 1 73  ? 149.445 106.857 138.005 1.00 73.09  ? 73  SER A OG    1 
ATOM 273  N N     . ILE A 1 74  ? 147.267 105.019 135.258 1.00 69.86  ? 74  ILE A N     1 
ATOM 274  C CA    . ILE A 1 74  ? 146.761 103.649 135.285 1.00 72.94  ? 74  ILE A CA    1 
ATOM 275  C C     . ILE A 1 74  ? 147.616 102.745 134.403 1.00 76.03  ? 74  ILE A C     1 
ATOM 276  O O     . ILE A 1 74  ? 147.999 101.640 134.808 1.00 78.36  ? 74  ILE A O     1 
ATOM 277  C CB    . ILE A 1 74  ? 145.281 103.611 134.869 1.00 74.90  ? 74  ILE A CB    1 
ATOM 278  C CG1   . ILE A 1 74  ? 144.407 104.234 135.952 1.00 71.57  ? 74  ILE A CG1   1 
ATOM 279  C CG2   . ILE A 1 74  ? 144.827 102.184 134.619 1.00 78.21  ? 74  ILE A CG2   1 
ATOM 280  C CD1   . ILE A 1 74  ? 143.073 104.690 135.440 1.00 72.55  ? 74  ILE A CD1   1 
ATOM 281  N N     . GLY A 1 75  ? 147.961 103.210 133.205 1.00 76.03  ? 75  GLY A N     1 
ATOM 282  C CA    . GLY A 1 75  ? 148.802 102.427 132.321 1.00 79.23  ? 75  GLY A CA    1 
ATOM 283  C C     . GLY A 1 75  ? 148.471 102.552 130.848 1.00 85.12  ? 75  GLY A C     1 
ATOM 284  O O     . GLY A 1 75  ? 149.343 102.347 129.999 1.00 90.31  ? 75  GLY A O     1 
ATOM 285  N N     . TYR A 1 76  ? 147.225 102.884 130.525 1.00 84.53  ? 76  TYR A N     1 
ATOM 286  C CA    . TYR A 1 76  ? 146.811 103.112 129.144 1.00 89.71  ? 76  TYR A CA    1 
ATOM 287  C C     . TYR A 1 76  ? 146.724 104.616 128.888 1.00 88.42  ? 76  TYR A C     1 
ATOM 288  O O     . TYR A 1 76  ? 145.888 105.313 129.469 1.00 83.69  ? 76  TYR A O     1 
ATOM 289  C CB    . TYR A 1 76  ? 145.516 102.350 128.837 1.00 88.45  ? 76  TYR A CB    1 
ATOM 290  C CG    . TYR A 1 76  ? 144.287 102.652 129.684 1.00 85.94  ? 76  TYR A CG    1 
ATOM 291  C CD1   . TYR A 1 76  ? 143.381 103.647 129.333 1.00 83.65  ? 76  TYR A CD1   1 
ATOM 292  C CD2   . TYR A 1 76  ? 144.021 101.902 130.823 1.00 81.69  ? 76  TYR A CD2   1 
ATOM 293  C CE1   . TYR A 1 76  ? 142.265 103.901 130.109 1.00 79.49  ? 76  TYR A CE1   1 
ATOM 294  C CE2   . TYR A 1 76  ? 142.906 102.145 131.598 1.00 78.97  ? 76  TYR A CE2   1 
ATOM 295  C CZ    . TYR A 1 76  ? 142.033 103.144 131.238 1.00 78.03  ? 76  TYR A CZ    1 
ATOM 296  O OH    . TYR A 1 76  ? 140.923 103.386 132.013 1.00 75.68  ? 76  TYR A OH    1 
ATOM 297  N N     . ASN A 1 77  ? 147.647 105.123 128.069 1.00 87.82  ? 77  ASN A N     1 
ATOM 298  C CA    . ASN A 1 77  ? 147.745 106.555 127.801 1.00 86.13  ? 77  ASN A CA    1 
ATOM 299  C C     . ASN A 1 77  ? 146.819 106.991 126.669 1.00 84.92  ? 77  ASN A C     1 
ATOM 300  O O     . ASN A 1 77  ? 145.893 107.779 126.880 1.00 83.64  ? 77  ASN A O     1 
ATOM 301  C CB    . ASN A 1 77  ? 149.194 106.925 127.466 1.00 85.51  ? 77  ASN A CB    1 
ATOM 302  C CG    . ASN A 1 77  ? 150.161 106.570 128.578 1.00 86.42  ? 77  ASN A CG    1 
ATOM 303  O OD1   . ASN A 1 77  ? 150.151 107.181 129.645 1.00 83.99  ? 77  ASN A OD1   1 
ATOM 304  N ND2   . ASN A 1 77  ? 151.003 105.574 128.332 1.00 88.35  ? 77  ASN A ND2   1 
ATOM 305  N N     . GLU A 1 78  ? 147.065 106.486 125.463 1.00 88.74  ? 78  GLU A N     1 
ATOM 306  C CA    . GLU A 1 78  ? 146.296 106.845 124.281 1.00 91.67  ? 78  GLU A CA    1 
ATOM 307  C C     . GLU A 1 78  ? 146.126 105.604 123.419 1.00 95.15  ? 78  GLU A C     1 
ATOM 308  O O     . GLU A 1 78  ? 146.676 104.540 123.714 1.00 96.91  ? 78  GLU A O     1 
ATOM 309  C CB    . GLU A 1 78  ? 146.969 107.964 123.464 1.00 92.53  ? 78  GLU A CB    1 
ATOM 310  C CG    . GLU A 1 78  ? 147.159 109.311 124.173 1.00 90.26  ? 78  GLU A CG    1 
ATOM 311  C CD    . GLU A 1 78  ? 145.859 110.024 124.520 1.00 84.17  ? 78  GLU A CD    1 
ATOM 312  O OE1   . GLU A 1 78  ? 144.786 109.648 123.999 1.00 80.36  ? 78  GLU A OE1   1 
ATOM 313  O OE2   . GLU A 1 78  ? 145.915 110.977 125.325 1.00 81.89  ? 78  GLU A OE2   1 
ATOM 314  N N     . SER A 1 79  ? 145.338 105.760 122.348 1.00 94.73  ? 79  SER A N     1 
ATOM 315  C CA    . SER A 1 79  ? 145.034 104.700 121.378 1.00 101.13 ? 79  SER A CA    1 
ATOM 316  C C     . SER A 1 79  ? 144.383 103.485 122.037 1.00 100.70 ? 79  SER A C     1 
ATOM 317  O O     . SER A 1 79  ? 144.499 102.360 121.545 1.00 102.56 ? 79  SER A O     1 
ATOM 318  C CB    . SER A 1 79  ? 146.277 104.280 120.583 1.00 106.62 ? 79  SER A CB    1 
ATOM 319  O OG    . SER A 1 79  ? 147.183 103.545 121.387 1.00 111.24 ? 79  SER A OG    1 
ATOM 320  N N     . THR A 1 80  ? 143.693 103.709 123.152 1.00 97.93  ? 80  THR A N     1 
ATOM 321  C CA    . THR A 1 80  ? 142.941 102.676 123.852 1.00 95.89  ? 80  THR A CA    1 
ATOM 322  C C     . THR A 1 80  ? 141.568 103.250 124.154 1.00 89.13  ? 80  THR A C     1 
ATOM 323  O O     . THR A 1 80  ? 141.458 104.206 124.927 1.00 85.89  ? 80  THR A O     1 
ATOM 324  C CB    . THR A 1 80  ? 143.644 102.246 125.141 1.00 96.79  ? 80  THR A CB    1 
ATOM 325  O OG1   . THR A 1 80  ? 144.999 101.880 124.849 1.00 101.44 ? 80  THR A OG1   1 
ATOM 326  C CG2   . THR A 1 80  ? 142.927 101.061 125.768 1.00 93.09  ? 80  THR A CG2   1 
ATOM 327  N N     . ALA A 1 81  ? 140.525 102.627 123.591 1.00 87.76  ? 81  ALA A N     1 
ATOM 328  C CA    . ALA A 1 81  ? 139.218 103.265 123.430 1.00 83.78  ? 81  ALA A CA    1 
ATOM 329  C C     . ALA A 1 81  ? 138.549 103.629 124.750 1.00 81.08  ? 81  ALA A C     1 
ATOM 330  O O     . ALA A 1 81  ? 137.580 104.397 124.744 1.00 80.26  ? 81  ALA A O     1 
ATOM 331  C CB    . ALA A 1 81  ? 138.292 102.356 122.622 1.00 82.06  ? 81  ALA A CB    1 
ATOM 332  N N     . THR A 1 82  ? 139.025 103.085 125.872 1.00 79.48  ? 82  THR A N     1 
ATOM 333  C CA    . THR A 1 82  ? 138.558 103.544 127.175 1.00 79.12  ? 82  THR A CA    1 
ATOM 334  C C     . THR A 1 82  ? 138.907 105.008 127.403 1.00 75.15  ? 82  THR A C     1 
ATOM 335  O O     . THR A 1 82  ? 138.082 105.778 127.914 1.00 69.27  ? 82  THR A O     1 
ATOM 336  C CB    . THR A 1 82  ? 139.167 102.681 128.277 1.00 81.35  ? 82  THR A CB    1 
ATOM 337  O OG1   . THR A 1 82  ? 140.506 102.323 127.915 1.00 82.36  ? 82  THR A OG1   1 
ATOM 338  C CG2   . THR A 1 82  ? 138.359 101.426 128.458 1.00 84.39  ? 82  THR A CG2   1 
ATOM 339  N N     . PHE A 1 83  ? 140.123 105.412 127.019 1.00 76.16  ? 83  PHE A N     1 
ATOM 340  C CA    . PHE A 1 83  ? 140.574 106.773 127.287 1.00 73.51  ? 83  PHE A CA    1 
ATOM 341  C C     . PHE A 1 83  ? 139.767 107.786 126.488 1.00 69.98  ? 83  PHE A C     1 
ATOM 342  O O     . PHE A 1 83  ? 139.334 108.803 127.037 1.00 65.87  ? 83  PHE A O     1 
ATOM 343  C CB    . PHE A 1 83  ? 142.076 106.904 126.997 1.00 71.58  ? 83  PHE A CB    1 
ATOM 344  C CG    . PHE A 1 83  ? 142.664 108.255 127.357 1.00 67.10  ? 83  PHE A CG    1 
ATOM 345  C CD1   . PHE A 1 83  ? 142.576 109.343 126.496 1.00 66.80  ? 83  PHE A CD1   1 
ATOM 346  C CD2   . PHE A 1 83  ? 143.280 108.438 128.580 1.00 67.55  ? 83  PHE A CD2   1 
ATOM 347  C CE1   . PHE A 1 83  ? 143.101 110.567 126.842 1.00 62.64  ? 83  PHE A CE1   1 
ATOM 348  C CE2   . PHE A 1 83  ? 143.809 109.663 128.930 1.00 67.10  ? 83  PHE A CE2   1 
ATOM 349  C CZ    . PHE A 1 83  ? 143.719 110.727 128.060 1.00 64.16  ? 83  PHE A CZ    1 
ATOM 350  N N     . GLU A 1 84  ? 139.566 107.533 125.190 1.00 72.63  ? 84  GLU A N     1 
ATOM 351  C CA    . GLU A 1 84  ? 138.809 108.476 124.370 1.00 74.14  ? 84  GLU A CA    1 
ATOM 352  C C     . GLU A 1 84  ? 137.368 108.592 124.847 1.00 67.38  ? 84  GLU A C     1 
ATOM 353  O O     . GLU A 1 84  ? 136.827 109.700 124.929 1.00 65.81  ? 84  GLU A O     1 
ATOM 354  C CB    . GLU A 1 84  ? 138.852 108.077 122.892 1.00 79.96  ? 84  GLU A CB    1 
ATOM 355  C CG    . GLU A 1 84  ? 140.190 108.308 122.192 1.00 86.25  ? 84  GLU A CG    1 
ATOM 356  C CD    . GLU A 1 84  ? 141.207 107.220 122.459 1.00 86.96  ? 84  GLU A CD    1 
ATOM 357  O OE1   . GLU A 1 84  ? 140.854 106.235 123.132 1.00 83.51  ? 84  GLU A OE1   1 
ATOM 358  O OE2   . GLU A 1 84  ? 142.361 107.349 121.996 1.00 89.66  ? 84  GLU A OE2   1 
ATOM 359  N N     . THR A 1 85  ? 136.754 107.466 125.217 1.00 63.93  ? 85  THR A N     1 
ATOM 360  C CA    . THR A 1 85  ? 135.366 107.485 125.669 1.00 60.89  ? 85  THR A CA    1 
ATOM 361  C C     . THR A 1 85  ? 135.217 108.240 126.985 1.00 59.09  ? 85  THR A C     1 
ATOM 362  O O     . THR A 1 85  ? 134.371 109.135 127.100 1.00 56.98  ? 85  THR A O     1 
ATOM 363  C CB    . THR A 1 85  ? 134.842 106.058 125.809 1.00 65.41  ? 85  THR A CB    1 
ATOM 364  O OG1   . THR A 1 85  ? 135.103 105.334 124.601 1.00 73.03  ? 85  THR A OG1   1 
ATOM 365  C CG2   . THR A 1 85  ? 133.347 106.066 126.073 1.00 62.17  ? 85  THR A CG2   1 
ATOM 366  N N     . VAL A 1 86  ? 136.050 107.917 127.979 1.00 59.35  ? 86  VAL A N     1 
ATOM 367  C CA    . VAL A 1 86  ? 135.944 108.575 129.281 1.00 54.14  ? 86  VAL A CA    1 
ATOM 368  C C     . VAL A 1 86  ? 136.310 110.053 129.175 1.00 54.37  ? 86  VAL A C     1 
ATOM 369  O O     . VAL A 1 86  ? 135.635 110.916 129.755 1.00 51.78  ? 86  VAL A O     1 
ATOM 370  C CB    . VAL A 1 86  ? 136.808 107.841 130.321 1.00 50.51  ? 86  VAL A CB    1 
ATOM 371  C CG1   . VAL A 1 86  ? 136.826 108.594 131.635 1.00 48.57  ? 86  VAL A CG1   1 
ATOM 372  C CG2   . VAL A 1 86  ? 136.274 106.442 130.545 1.00 58.93  ? 86  VAL A CG2   1 
ATOM 373  N N     . TYR A 1 87  ? 137.362 110.372 128.415 1.00 55.56  ? 87  TYR A N     1 
ATOM 374  C CA    . TYR A 1 87  ? 137.796 111.755 128.269 1.00 50.90  ? 87  TYR A CA    1 
ATOM 375  C C     . TYR A 1 87  ? 136.751 112.591 127.538 1.00 51.59  ? 87  TYR A C     1 
ATOM 376  O O     . TYR A 1 87  ? 136.487 113.734 127.924 1.00 50.46  ? 87  TYR A O     1 
ATOM 377  C CB    . TYR A 1 87  ? 139.136 111.789 127.535 1.00 50.88  ? 87  TYR A CB    1 
ATOM 378  C CG    . TYR A 1 87  ? 139.900 113.081 127.673 1.00 43.30  ? 87  TYR A CG    1 
ATOM 379  C CD1   . TYR A 1 87  ? 140.652 113.340 128.806 1.00 43.46  ? 87  TYR A CD1   1 
ATOM 380  C CD2   . TYR A 1 87  ? 139.882 114.032 126.668 1.00 43.93  ? 87  TYR A CD2   1 
ATOM 381  C CE1   . TYR A 1 87  ? 141.357 114.514 128.937 1.00 41.62  ? 87  TYR A CE1   1 
ATOM 382  C CE2   . TYR A 1 87  ? 140.585 115.210 126.790 1.00 42.46  ? 87  TYR A CE2   1 
ATOM 383  C CZ    . TYR A 1 87  ? 141.320 115.445 127.926 1.00 40.68  ? 87  TYR A CZ    1 
ATOM 384  O OH    . TYR A 1 87  ? 142.023 116.618 128.053 1.00 43.38  ? 87  TYR A OH    1 
ATOM 385  N N     . SER A 1 88  ? 136.132 112.037 126.490 1.00 49.44  ? 88  SER A N     1 
ATOM 386  C CA    . SER A 1 88  ? 135.066 112.752 125.802 1.00 46.22  ? 88  SER A CA    1 
ATOM 387  C C     . SER A 1 88  ? 133.805 112.857 126.645 1.00 47.68  ? 88  SER A C     1 
ATOM 388  O O     . SER A 1 88  ? 133.020 113.789 126.445 1.00 51.31  ? 88  SER A O     1 
ATOM 389  C CB    . SER A 1 88  ? 134.746 112.067 124.476 1.00 49.18  ? 88  SER A CB    1 
ATOM 390  O OG    . SER A 1 88  ? 134.314 110.736 124.685 1.00 56.01  ? 88  SER A OG    1 
ATOM 391  N N     . LEU A 1 89  ? 133.585 111.921 127.570 1.00 49.83  ? 89  LEU A N     1 
ATOM 392  C CA    . LEU A 1 89  ? 132.490 112.076 128.520 1.00 49.00  ? 89  LEU A CA    1 
ATOM 393  C C     . LEU A 1 89  ? 132.772 113.197 129.510 1.00 44.99  ? 89  LEU A C     1 
ATOM 394  O O     . LEU A 1 89  ? 131.849 113.902 129.933 1.00 44.68  ? 89  LEU A O     1 
ATOM 395  C CB    . LEU A 1 89  ? 132.239 110.764 129.258 1.00 48.16  ? 89  LEU A CB    1 
ATOM 396  C CG    . LEU A 1 89  ? 131.491 109.693 128.474 1.00 48.43  ? 89  LEU A CG    1 
ATOM 397  C CD1   . LEU A 1 89  ? 131.647 108.349 129.152 1.00 57.81  ? 89  LEU A CD1   1 
ATOM 398  C CD2   . LEU A 1 89  ? 130.033 110.066 128.348 1.00 54.03  ? 89  LEU A CD2   1 
ATOM 399  N N     . ALA A 1 90  ? 134.040 113.366 129.898 1.00 42.98  ? 90  ALA A N     1 
ATOM 400  C CA    . ALA A 1 90  ? 134.399 114.335 130.931 1.00 41.42  ? 90  ALA A CA    1 
ATOM 401  C C     . ALA A 1 90  ? 134.138 115.776 130.527 1.00 40.76  ? 90  ALA A C     1 
ATOM 402  O O     . ALA A 1 90  ? 134.091 116.649 131.398 1.00 37.86  ? 90  ALA A O     1 
ATOM 403  C CB    . ALA A 1 90  ? 135.868 114.187 131.308 1.00 38.36  ? 90  ALA A CB    1 
ATOM 404  N N     . HIS A 1 91  ? 133.985 116.054 129.236 1.00 40.15  ? 91  HIS A N     1 
ATOM 405  C CA    . HIS A 1 91  ? 133.690 117.418 128.823 1.00 38.01  ? 91  HIS A CA    1 
ATOM 406  C C     . HIS A 1 91  ? 132.258 117.804 129.166 1.00 38.55  ? 91  HIS A C     1 
ATOM 407  O O     . HIS A 1 91  ? 131.965 118.989 129.356 1.00 38.01  ? 91  HIS A O     1 
ATOM 408  C CB    . HIS A 1 91  ? 133.930 117.586 127.322 1.00 37.94  ? 91  HIS A CB    1 
ATOM 409  C CG    . HIS A 1 91  ? 135.370 117.503 126.920 1.00 37.00  ? 91  HIS A CG    1 
ATOM 410  N ND1   . HIS A 1 91  ? 135.900 118.264 125.902 1.00 39.88  ? 91  HIS A ND1   1 
ATOM 411  C CD2   . HIS A 1 91  ? 136.385 116.737 127.382 1.00 35.74  ? 91  HIS A CD2   1 
ATOM 412  C CE1   . HIS A 1 91  ? 137.181 117.978 125.763 1.00 40.20  ? 91  HIS A CE1   1 
ATOM 413  N NE2   . HIS A 1 91  ? 137.500 117.054 126.650 1.00 35.25  ? 91  HIS A NE2   1 
ATOM 414  N N     . LYS A 1 92  ? 131.359 116.822 129.247 1.00 35.37  ? 92  LYS A N     1 
ATOM 415  C CA    . LYS A 1 92  ? 129.920 117.052 129.363 1.00 36.90  ? 92  LYS A CA    1 
ATOM 416  C C     . LYS A 1 92  ? 129.366 116.258 130.554 1.00 40.80  ? 92  LYS A C     1 
ATOM 417  O O     . LYS A 1 92  ? 128.410 115.494 130.432 1.00 50.09  ? 92  LYS A O     1 
ATOM 418  C CB    . LYS A 1 92  ? 129.222 116.699 128.046 1.00 40.19  ? 92  LYS A CB    1 
ATOM 419  C CG    . LYS A 1 92  ? 129.739 117.493 126.846 1.00 42.09  ? 92  LYS A CG    1 
ATOM 420  C CD    . LYS A 1 92  ? 129.085 117.091 125.539 1.00 44.69  ? 92  LYS A CD    1 
ATOM 421  C CE    . LYS A 1 92  ? 127.740 117.763 125.364 1.00 49.45  ? 92  LYS A CE    1 
ATOM 422  N NZ    . LYS A 1 92  ? 127.885 119.125 124.784 1.00 48.46  ? 92  LYS A NZ    1 
ATOM 423  N N     . ARG A 1 93  ? 129.993 116.442 131.721 1.00 38.58  ? 93  ARG A N     1 
ATOM 424  C CA    . ARG A 1 93  ? 129.860 115.547 132.867 1.00 37.17  ? 93  ARG A CA    1 
ATOM 425  C C     . ARG A 1 93  ? 128.505 115.588 133.573 1.00 42.74  ? 93  ARG A C     1 
ATOM 426  O O     . ARG A 1 93  ? 128.227 114.675 134.355 1.00 54.62  ? 93  ARG A O     1 
ATOM 427  C CB    . ARG A 1 93  ? 130.963 115.862 133.881 1.00 35.09  ? 93  ARG A CB    1 
ATOM 428  C CG    . ARG A 1 93  ? 130.797 117.200 134.570 1.00 35.77  ? 93  ARG A CG    1 
ATOM 429  C CD    . ARG A 1 93  ? 131.768 117.353 135.716 1.00 40.07  ? 93  ARG A CD    1 
ATOM 430  N NE    . ARG A 1 93  ? 131.526 118.570 136.478 1.00 44.02  ? 93  ARG A NE    1 
ATOM 431  C CZ    . ARG A 1 93  ? 131.306 118.604 137.784 1.00 43.97  ? 93  ARG A CZ    1 
ATOM 432  N NH1   . ARG A 1 93  ? 131.302 117.501 138.513 1.00 42.39  ? 93  ARG A NH1   1 
ATOM 433  N NH2   . ARG A 1 93  ? 131.103 119.776 138.377 1.00 44.91  ? 93  ARG A NH2   1 
ATOM 434  N N     . GLY A 1 94  ? 127.656 116.585 133.336 1.00 41.24  ? 94  GLY A N     1 
ATOM 435  C CA    . GLY A 1 94  ? 126.314 116.568 133.897 1.00 46.05  ? 94  GLY A CA    1 
ATOM 436  C C     . GLY A 1 94  ? 126.127 117.519 135.071 1.00 48.65  ? 94  GLY A C     1 
ATOM 437  O O     . GLY A 1 94  ? 127.057 118.185 135.536 1.00 54.58  ? 94  GLY A O     1 
ATOM 438  N N     . TYR A 1 95  ? 124.892 117.540 135.590 1.00 50.31  ? 95  TYR A N     1 
ATOM 439  C CA    . TYR A 1 95  ? 124.405 118.634 136.434 1.00 57.85  ? 95  TYR A CA    1 
ATOM 440  C C     . TYR A 1 95  ? 123.669 118.137 137.690 1.00 69.53  ? 95  TYR A C     1 
ATOM 441  O O     . TYR A 1 95  ? 122.676 118.734 138.121 1.00 78.91  ? 95  TYR A O     1 
ATOM 442  C CB    . TYR A 1 95  ? 123.509 119.580 135.624 1.00 57.03  ? 95  TYR A CB    1 
ATOM 443  C CG    . TYR A 1 95  ? 122.222 118.983 135.061 1.00 60.58  ? 95  TYR A CG    1 
ATOM 444  C CD1   . TYR A 1 95  ? 121.038 118.981 135.785 1.00 61.92  ? 95  TYR A CD1   1 
ATOM 445  C CD2   . TYR A 1 95  ? 122.191 118.479 133.768 1.00 67.25  ? 95  TYR A CD2   1 
ATOM 446  C CE1   . TYR A 1 95  ? 119.875 118.461 135.255 1.00 65.01  ? 95  TYR A CE1   1 
ATOM 447  C CE2   . TYR A 1 95  ? 121.028 117.959 133.230 1.00 75.49  ? 95  TYR A CE2   1 
ATOM 448  C CZ    . TYR A 1 95  ? 119.874 117.956 133.982 1.00 74.37  ? 95  TYR A CZ    1 
ATOM 449  O OH    . TYR A 1 95  ? 118.703 117.449 133.470 1.00 88.76  ? 95  TYR A OH    1 
ATOM 450  N N     . ASP A 1 96  ? 124.177 117.078 138.336 1.00 70.27  ? 96  ASP A N     1 
ATOM 451  C CA    . ASP A 1 96  ? 123.497 116.475 139.491 1.00 76.62  ? 96  ASP A CA    1 
ATOM 452  C C     . ASP A 1 96  ? 123.339 117.439 140.666 1.00 81.14  ? 96  ASP A C     1 
ATOM 453  O O     . ASP A 1 96  ? 122.370 117.333 141.428 1.00 83.39  ? 96  ASP A O     1 
ATOM 454  C CB    . ASP A 1 96  ? 124.264 115.231 139.946 1.00 75.02  ? 96  ASP A CB    1 
ATOM 455  C CG    . ASP A 1 96  ? 123.840 114.736 141.315 1.00 82.09  ? 96  ASP A CG    1 
ATOM 456  O OD1   . ASP A 1 96  ? 122.733 114.173 141.436 1.00 81.00  ? 96  ASP A OD1   1 
ATOM 457  O OD2   . ASP A 1 96  ? 124.617 114.915 142.275 1.00 82.00  ? 96  ASP A OD2   1 
ATOM 458  N N     . TYR A 1 97  ? 124.252 118.403 140.795 1.00 77.84  ? 97  TYR A N     1 
ATOM 459  C CA    . TYR A 1 97  ? 124.334 119.257 141.979 1.00 83.33  ? 97  TYR A CA    1 
ATOM 460  C C     . TYR A 1 97  ? 123.082 120.107 142.176 1.00 85.95  ? 97  TYR A C     1 
ATOM 461  O O     . TYR A 1 97  ? 122.731 120.438 143.314 1.00 82.56  ? 97  TYR A O     1 
ATOM 462  C CB    . TYR A 1 97  ? 125.588 120.132 141.865 1.00 80.12  ? 97  TYR A CB    1 
ATOM 463  C CG    . TYR A 1 97  ? 125.630 120.957 140.594 1.00 74.19  ? 97  TYR A CG    1 
ATOM 464  C CD1   . TYR A 1 97  ? 125.021 122.204 140.522 1.00 75.18  ? 97  TYR A CD1   1 
ATOM 465  C CD2   . TYR A 1 97  ? 126.222 120.454 139.444 1.00 69.75  ? 97  TYR A CD2   1 
ATOM 466  C CE1   . TYR A 1 97  ? 125.035 122.937 139.360 1.00 70.27  ? 97  TYR A CE1   1 
ATOM 467  C CE2   . TYR A 1 97  ? 126.226 121.171 138.280 1.00 66.70  ? 97  TYR A CE2   1 
ATOM 468  C CZ    . TYR A 1 97  ? 125.642 122.414 138.243 1.00 66.21  ? 97  TYR A CZ    1 
ATOM 469  O OH    . TYR A 1 97  ? 125.663 123.132 137.076 1.00 61.19  ? 97  TYR A OH    1 
ATOM 470  N N     . ALA A 1 98  ? 122.399 120.462 141.093 1.00 85.86  ? 98  ALA A N     1 
ATOM 471  C CA    . ALA A 1 98  ? 121.207 121.296 141.143 1.00 90.57  ? 98  ALA A CA    1 
ATOM 472  C C     . ALA A 1 98  ? 120.027 120.595 140.489 1.00 103.21 ? 98  ALA A C     1 
ATOM 473  O O     . ALA A 1 98  ? 119.300 121.184 139.687 1.00 109.09 ? 98  ALA A O     1 
ATOM 474  C CB    . ALA A 1 98  ? 121.459 122.650 140.485 1.00 86.06  ? 98  ALA A CB    1 
ATOM 475  N N     . ASP A 1 99  ? 119.838 119.317 140.809 1.00 102.88 ? 99  ASP A N     1 
ATOM 476  C CA    . ASP A 1 99  ? 118.696 118.577 140.292 1.00 113.88 ? 99  ASP A CA    1 
ATOM 477  C C     . ASP A 1 99  ? 117.412 119.137 140.894 1.00 128.34 ? 99  ASP A C     1 
ATOM 478  O O     . ASP A 1 99  ? 117.304 119.279 142.117 1.00 130.41 ? 99  ASP A O     1 
ATOM 479  C CB    . ASP A 1 99  ? 118.840 117.091 140.613 1.00 108.33 ? 99  ASP A CB    1 
ATOM 480  C CG    . ASP A 1 99  ? 117.807 116.235 139.907 1.00 114.09 ? 99  ASP A CG    1 
ATOM 481  O OD1   . ASP A 1 99  ? 117.129 116.745 138.990 1.00 114.27 ? 99  ASP A OD1   1 
ATOM 482  O OD2   . ASP A 1 99  ? 117.678 115.046 140.267 1.00 114.60 ? 99  ASP A OD2   1 
ATOM 483  N N     . MET A 1 100 ? 116.446 119.439 140.026 1.00 132.53 ? 100 MET A N     1 
ATOM 484  C CA    . MET A 1 100 ? 115.227 120.158 140.378 1.00 136.74 ? 100 MET A CA    1 
ATOM 485  C C     . MET A 1 100 ? 115.515 121.462 141.128 1.00 144.05 ? 100 MET A C     1 
ATOM 486  O O     . MET A 1 100 ? 115.135 121.611 142.295 1.00 151.93 ? 100 MET A O     1 
ATOM 487  C CB    . MET A 1 100 ? 114.280 119.272 141.181 1.00 135.86 ? 100 MET A CB    1 
ATOM 488  N N     . PRO A 1 101 ? 116.182 122.425 140.488 1.00 144.02 ? 101 PRO A N     1 
ATOM 489  C CA    . PRO A 1 101 ? 116.576 123.646 141.201 1.00 151.12 ? 101 PRO A CA    1 
ATOM 490  C C     . PRO A 1 101 ? 115.423 124.632 141.361 1.00 166.91 ? 101 PRO A C     1 
ATOM 491  O O     . PRO A 1 101 ? 114.666 124.892 140.420 1.00 165.86 ? 101 PRO A O     1 
ATOM 492  C CB    . PRO A 1 101 ? 117.698 124.203 140.321 1.00 139.29 ? 101 PRO A CB    1 
ATOM 493  C CG    . PRO A 1 101 ? 117.260 123.843 138.919 1.00 136.45 ? 101 PRO A CG    1 
ATOM 494  C CD    . PRO A 1 101 ? 116.384 122.580 139.033 1.00 138.00 ? 101 PRO A CD    1 
ATOM 495  N N     . GLU A 1 102 ? 115.292 125.165 142.581 1.00 176.86 ? 102 GLU A N     1 
ATOM 496  C CA    . GLU A 1 102 ? 114.251 126.122 142.967 1.00 187.38 ? 102 GLU A CA    1 
ATOM 497  C C     . GLU A 1 102 ? 112.849 125.558 142.717 1.00 193.75 ? 102 GLU A C     1 
ATOM 498  O O     . GLU A 1 102 ? 112.086 126.053 141.885 1.00 197.89 ? 102 GLU A O     1 
ATOM 499  C CB    . GLU A 1 102 ? 114.443 127.472 142.260 1.00 189.98 ? 102 GLU A CB    1 
ATOM 500  C CG    . GLU A 1 102 ? 115.816 128.132 142.448 1.00 189.39 ? 102 GLU A CG    1 
ATOM 501  C CD    . GLU A 1 102 ? 116.175 128.443 143.900 1.00 195.47 ? 102 GLU A CD    1 
ATOM 502  O OE1   . GLU A 1 102 ? 115.271 128.540 144.759 1.00 199.49 ? 102 GLU A OE1   1 
ATOM 503  O OE2   . GLU A 1 102 ? 117.383 128.597 144.183 1.00 195.37 ? 102 GLU A OE2   1 
ATOM 504  N N     . GLU A 1 103 ? 112.531 124.493 143.450 1.00 192.23 ? 103 GLU A N     1 
ATOM 505  C CA    . GLU A 1 103 ? 111.190 123.928 143.411 1.00 198.50 ? 103 GLU A CA    1 
ATOM 506  C C     . GLU A 1 103 ? 110.189 124.915 143.998 1.00 209.11 ? 103 GLU A C     1 
ATOM 507  O O     . GLU A 1 103 ? 110.456 125.567 145.011 1.00 210.89 ? 103 GLU A O     1 
ATOM 508  C CB    . GLU A 1 103 ? 111.145 122.606 144.177 1.00 194.21 ? 103 GLU A CB    1 
ATOM 509  N N     . LYS A 1 104 ? 109.030 125.027 143.355 1.00 213.96 ? 104 LYS A N     1 
ATOM 510  C CA    . LYS A 1 104 ? 108.083 126.071 143.714 1.00 219.17 ? 104 LYS A CA    1 
ATOM 511  C C     . LYS A 1 104 ? 106.679 125.607 143.352 1.00 225.23 ? 104 LYS A C     1 
ATOM 512  O O     . LYS A 1 104 ? 106.493 124.832 142.410 1.00 224.24 ? 104 LYS A O     1 
ATOM 513  C CB    . LYS A 1 104 ? 108.437 127.383 142.999 1.00 216.89 ? 104 LYS A CB    1 
ATOM 514  C CG    . LYS A 1 104 ? 107.709 128.621 143.497 1.00 219.86 ? 104 LYS A CG    1 
ATOM 515  C CD    . LYS A 1 104 ? 108.350 129.881 142.939 1.00 215.97 ? 104 LYS A CD    1 
ATOM 516  C CE    . LYS A 1 104 ? 109.706 130.146 143.576 1.00 212.97 ? 104 LYS A CE    1 
ATOM 517  N NZ    . LYS A 1 104 ? 109.581 130.762 144.925 1.00 215.65 ? 104 LYS A NZ    1 
ATOM 518  N N     . THR A 1 105 ? 105.696 126.088 144.109 1.00 228.98 ? 105 THR A N     1 
ATOM 519  C CA    . THR A 1 105 ? 104.294 125.769 143.887 1.00 231.55 ? 105 THR A CA    1 
ATOM 520  C C     . THR A 1 105 ? 103.589 126.938 143.211 1.00 233.40 ? 105 THR A C     1 
ATOM 521  O O     . THR A 1 105 ? 104.064 128.077 143.233 1.00 232.80 ? 105 THR A O     1 
ATOM 522  C CB    . THR A 1 105 ? 103.593 125.409 145.204 1.00 230.81 ? 105 THR A CB    1 
ATOM 523  O OG1   . THR A 1 105 ? 102.340 124.773 144.924 1.00 232.29 ? 105 THR A OG1   1 
ATOM 524  C CG2   . THR A 1 105 ? 103.357 126.646 146.060 1.00 230.12 ? 105 THR A CG2   1 
ATOM 525  N N     . SER A 1 106 ? 102.442 126.632 142.595 1.00 235.79 ? 106 SER A N     1 
ATOM 526  C CA    . SER A 1 106 ? 101.759 127.611 141.755 1.00 235.14 ? 106 SER A CA    1 
ATOM 527  C C     . SER A 1 106 ? 101.137 128.733 142.576 1.00 235.41 ? 106 SER A C     1 
ATOM 528  O O     . SER A 1 106 ? 101.020 129.862 142.084 1.00 235.44 ? 106 SER A O     1 
ATOM 529  C CB    . SER A 1 106 ? 100.690 126.924 140.907 1.00 233.91 ? 106 SER A CB    1 
ATOM 530  O OG    . SER A 1 106 ? 100.215 127.794 139.894 1.00 231.50 ? 106 SER A OG    1 
ATOM 531  N N     . GLU A 1 107 ? 100.719 128.444 143.812 1.00 236.11 ? 107 GLU A N     1 
ATOM 532  C CA    . GLU A 1 107 ? 100.213 129.500 144.685 1.00 234.92 ? 107 GLU A CA    1 
ATOM 533  C C     . GLU A 1 107 ? 101.317 130.473 145.076 1.00 232.60 ? 107 GLU A C     1 
ATOM 534  O O     . GLU A 1 107 ? 101.038 131.648 145.346 1.00 232.20 ? 107 GLU A O     1 
ATOM 535  C CB    . GLU A 1 107 ? 99.542  128.944 145.959 1.00 234.43 ? 107 GLU A CB    1 
ATOM 536  C CG    . GLU A 1 107 ? 98.398  127.874 145.885 1.00 234.60 ? 107 GLU A CG    1 
ATOM 537  C CD    . GLU A 1 107 ? 98.651  126.663 145.006 1.00 234.09 ? 107 GLU A CD    1 
ATOM 538  O OE1   . GLU A 1 107 ? 99.788  126.145 145.025 1.00 234.38 ? 107 GLU A OE1   1 
ATOM 539  O OE2   . GLU A 1 107 ? 97.715  126.229 144.301 1.00 232.13 ? 107 GLU A OE2   1 
ATOM 540  N N     . GLU A 1 108 ? 102.569 130.010 145.098 1.00 231.32 ? 108 GLU A N     1 
ATOM 541  C CA    . GLU A 1 108 ? 103.693 130.912 145.309 1.00 229.72 ? 108 GLU A CA    1 
ATOM 542  C C     . GLU A 1 108 ? 104.013 131.710 144.054 1.00 230.54 ? 108 GLU A C     1 
ATOM 543  O O     . GLU A 1 108 ? 104.406 132.875 144.159 1.00 230.34 ? 108 GLU A O     1 
ATOM 544  C CB    . GLU A 1 108 ? 104.927 130.129 145.759 1.00 228.13 ? 108 GLU A CB    1 
ATOM 545  C CG    . GLU A 1 108 ? 105.975 130.961 146.480 1.00 224.25 ? 108 GLU A CG    1 
ATOM 546  C CD    . GLU A 1 108 ? 106.691 130.183 147.574 1.00 221.59 ? 108 GLU A CD    1 
ATOM 547  O OE1   . GLU A 1 108 ? 106.774 128.938 147.473 1.00 223.95 ? 108 GLU A OE1   1 
ATOM 548  O OE2   . GLU A 1 108 ? 107.173 130.824 148.529 1.00 211.35 ? 108 GLU A OE2   1 
ATOM 549  N N     . ILE A 1 109 ? 103.837 131.108 142.870 1.00 231.50 ? 109 ILE A N     1 
ATOM 550  C CA    . ILE A 1 109 ? 104.061 131.821 141.610 1.00 229.78 ? 109 ILE A CA    1 
ATOM 551  C C     . ILE A 1 109 ? 103.070 132.973 141.470 1.00 231.88 ? 109 ILE A C     1 
ATOM 552  O O     . ILE A 1 109 ? 103.395 134.040 140.933 1.00 230.10 ? 109 ILE A O     1 
ATOM 553  C CB    . ILE A 1 109 ? 103.990 130.839 140.422 1.00 225.31 ? 109 ILE A CB    1 
ATOM 554  C CG1   . ILE A 1 109 ? 105.015 129.715 140.600 1.00 218.96 ? 109 ILE A CG1   1 
ATOM 555  C CG2   . ILE A 1 109 ? 104.251 131.554 139.099 1.00 219.32 ? 109 ILE A CG2   1 
ATOM 556  C CD1   . ILE A 1 109 ? 104.859 128.584 139.605 1.00 214.36 ? 109 ILE A CD1   1 
ATOM 557  N N     . GLU A 1 110 ? 101.854 132.787 141.979 1.00 233.48 ? 110 GLU A N     1 
ATOM 558  C CA    . GLU A 1 110 ? 100.858 133.849 142.006 1.00 233.44 ? 110 GLU A CA    1 
ATOM 559  C C     . GLU A 1 110 ? 101.173 134.936 143.025 1.00 232.67 ? 110 GLU A C     1 
ATOM 560  O O     . GLU A 1 110 ? 100.480 135.957 143.038 1.00 233.86 ? 110 GLU A O     1 
ATOM 561  C CB    . GLU A 1 110 ? 99.478  133.262 142.309 1.00 234.20 ? 110 GLU A CB    1 
ATOM 562  C CG    . GLU A 1 110 ? 98.921  132.400 141.193 1.00 233.26 ? 110 GLU A CG    1 
ATOM 563  C CD    . GLU A 1 110 ? 97.838  131.457 141.672 1.00 231.94 ? 110 GLU A CD    1 
ATOM 564  O OE1   . GLU A 1 110 ? 97.015  131.876 142.513 1.00 230.55 ? 110 GLU A OE1   1 
ATOM 565  O OE2   . GLU A 1 110 ? 97.803  130.299 141.205 1.00 232.55 ? 110 GLU A OE2   1 
ATOM 566  N N     . ALA A 1 111 ? 102.184 134.748 143.875 1.00 231.94 ? 111 ALA A N     1 
ATOM 567  C CA    . ALA A 1 111 ? 102.381 135.607 145.037 1.00 231.66 ? 111 ALA A CA    1 
ATOM 568  C C     . ALA A 1 111 ? 103.437 136.693 144.853 1.00 233.24 ? 111 ALA A C     1 
ATOM 569  O O     . ALA A 1 111 ? 103.226 137.821 145.309 1.00 234.00 ? 111 ALA A O     1 
ATOM 570  C CB    . ALA A 1 111 ? 102.749 134.760 146.259 1.00 229.26 ? 111 ALA A CB    1 
ATOM 571  N N     . MET A 1 112 ? 104.571 136.400 144.217 1.00 232.86 ? 112 MET A N     1 
ATOM 572  C CA    . MET A 1 112 ? 105.682 137.340 144.286 1.00 230.38 ? 112 MET A CA    1 
ATOM 573  C C     . MET A 1 112 ? 105.513 138.497 143.295 1.00 228.76 ? 112 MET A C     1 
ATOM 574  O O     . MET A 1 112 ? 104.519 138.610 142.571 1.00 230.09 ? 112 MET A O     1 
ATOM 575  C CB    . MET A 1 112 ? 107.029 136.649 144.050 1.00 228.62 ? 112 MET A CB    1 
ATOM 576  C CG    . MET A 1 112 ? 107.312 136.181 142.623 1.00 226.77 ? 112 MET A CG    1 
ATOM 577  S SD    . MET A 1 112 ? 106.272 134.879 141.997 1.00 228.22 ? 112 MET A SD    1 
ATOM 578  C CE    . MET A 1 112 ? 107.146 133.492 142.709 1.00 226.66 ? 112 MET A CE    1 
ATOM 579  N N     . ASP A 1 113 ? 106.530 139.358 143.263 1.00 226.17 ? 113 ASP A N     1 
ATOM 580  C CA    . ASP A 1 113 ? 106.560 140.559 142.443 1.00 224.78 ? 113 ASP A CA    1 
ATOM 581  C C     . ASP A 1 113 ? 106.865 140.200 140.986 1.00 223.96 ? 113 ASP A C     1 
ATOM 582  O O     . ASP A 1 113 ? 107.165 139.050 140.650 1.00 224.15 ? 113 ASP A O     1 
ATOM 583  C CB    . ASP A 1 113 ? 107.600 141.537 143.001 1.00 222.67 ? 113 ASP A CB    1 
ATOM 584  C CG    . ASP A 1 113 ? 107.376 142.973 142.544 1.00 220.19 ? 113 ASP A CG    1 
ATOM 585  O OD1   . ASP A 1 113 ? 106.357 143.234 141.869 1.00 220.79 ? 113 ASP A OD1   1 
ATOM 586  O OD2   . ASP A 1 113 ? 108.224 143.838 142.854 1.00 215.86 ? 113 ASP A OD2   1 
ATOM 587  N N     . VAL A 1 114 ? 106.768 141.209 140.114 1.00 223.18 ? 114 VAL A N     1 
ATOM 588  C CA    . VAL A 1 114 ? 106.999 141.018 138.682 1.00 222.02 ? 114 VAL A CA    1 
ATOM 589  C C     . VAL A 1 114 ? 108.450 140.632 138.408 1.00 221.27 ? 114 VAL A C     1 
ATOM 590  O O     . VAL A 1 114 ? 108.725 139.750 137.583 1.00 220.38 ? 114 VAL A O     1 
ATOM 591  C CB    . VAL A 1 114 ? 106.594 142.288 137.910 1.00 220.45 ? 114 VAL A CB    1 
ATOM 592  C CG1   . VAL A 1 114 ? 106.811 142.102 136.421 1.00 219.65 ? 114 VAL A CG1   1 
ATOM 593  C CG2   . VAL A 1 114 ? 105.145 142.645 138.201 1.00 218.76 ? 114 VAL A CG2   1 
ATOM 594  N N     . GLU A 1 115 ? 109.398 141.291 139.086 1.00 222.07 ? 115 GLU A N     1 
ATOM 595  C CA    . GLU A 1 115 ? 110.815 140.999 138.876 1.00 219.35 ? 115 GLU A CA    1 
ATOM 596  C C     . GLU A 1 115 ? 111.158 139.568 139.280 1.00 218.43 ? 115 GLU A C     1 
ATOM 597  O O     . GLU A 1 115 ? 111.844 138.852 138.539 1.00 216.05 ? 115 GLU A O     1 
ATOM 598  C CB    . GLU A 1 115 ? 111.675 141.991 139.662 1.00 215.72 ? 115 GLU A CB    1 
ATOM 599  C CG    . GLU A 1 115 ? 111.519 143.448 139.246 1.00 214.00 ? 115 GLU A CG    1 
ATOM 600  C CD    . GLU A 1 115 ? 111.781 143.675 137.771 1.00 216.40 ? 115 GLU A CD    1 
ATOM 601  O OE1   . GLU A 1 115 ? 112.776 143.127 137.249 1.00 217.78 ? 115 GLU A OE1   1 
ATOM 602  O OE2   . GLU A 1 115 ? 110.991 144.401 137.133 1.00 216.44 ? 115 GLU A OE2   1 
ATOM 603  N N     . GLU A 1 116 ? 110.659 139.125 140.436 1.00 220.61 ? 116 GLU A N     1 
ATOM 604  C CA    . GLU A 1 116 ? 110.963 137.779 140.910 1.00 220.13 ? 116 GLU A CA    1 
ATOM 605  C C     . GLU A 1 116 ? 110.289 136.713 140.050 1.00 217.04 ? 116 GLU A C     1 
ATOM 606  O O     . GLU A 1 116 ? 110.871 135.649 139.813 1.00 213.36 ? 116 GLU A O     1 
ATOM 607  C CB    . GLU A 1 116 ? 110.556 137.633 142.378 1.00 222.72 ? 116 GLU A CB    1 
ATOM 608  C CG    . GLU A 1 116 ? 111.440 138.344 143.404 1.00 224.34 ? 116 GLU A CG    1 
ATOM 609  C CD    . GLU A 1 116 ? 112.715 137.584 143.769 1.00 223.39 ? 116 GLU A CD    1 
ATOM 610  O OE1   . GLU A 1 116 ? 113.359 136.981 142.882 1.00 220.32 ? 116 GLU A OE1   1 
ATOM 611  O OE2   . GLU A 1 116 ? 113.076 137.594 144.967 1.00 222.36 ? 116 GLU A OE2   1 
ATOM 612  N N     . ARG A 1 117 ? 109.074 136.974 139.554 1.00 218.54 ? 117 ARG A N     1 
ATOM 613  C CA    . ARG A 1 117 ? 108.437 135.964 138.711 1.00 215.30 ? 117 ARG A CA    1 
ATOM 614  C C     . ARG A 1 117 ? 109.049 135.918 137.315 1.00 211.35 ? 117 ARG A C     1 
ATOM 615  O O     . ARG A 1 117 ? 109.124 134.837 136.719 1.00 207.63 ? 117 ARG A O     1 
ATOM 616  C CB    . ARG A 1 117 ? 106.920 136.181 138.627 1.00 217.98 ? 117 ARG A CB    1 
ATOM 617  C CG    . ARG A 1 117 ? 106.458 137.432 137.907 1.00 218.58 ? 117 ARG A CG    1 
ATOM 618  C CD    . ARG A 1 117 ? 104.942 137.542 137.917 1.00 220.62 ? 117 ARG A CD    1 
ATOM 619  N NE    . ARG A 1 117 ? 104.417 137.832 139.247 1.00 223.32 ? 117 ARG A NE    1 
ATOM 620  C CZ    . ARG A 1 117 ? 103.146 137.688 139.596 1.00 224.50 ? 117 ARG A CZ    1 
ATOM 621  N NH1   . ARG A 1 117 ? 102.238 137.258 138.736 1.00 222.32 ? 117 ARG A NH1   1 
ATOM 622  N NH2   . ARG A 1 117 ? 102.778 137.983 140.839 1.00 227.94 ? 117 ARG A NH2   1 
ATOM 623  N N     . LYS A 1 118 ? 109.518 137.056 136.788 1.00 213.92 ? 118 LYS A N     1 
ATOM 624  C CA    . LYS A 1 118 ? 110.278 137.027 135.542 1.00 211.75 ? 118 LYS A CA    1 
ATOM 625  C C     . LYS A 1 118 ? 111.596 136.286 135.727 1.00 206.70 ? 118 LYS A C     1 
ATOM 626  O O     . LYS A 1 118 ? 112.025 135.536 134.841 1.00 201.01 ? 118 LYS A O     1 
ATOM 627  C CB    . LYS A 1 118 ? 110.528 138.448 135.036 1.00 213.07 ? 118 LYS A CB    1 
ATOM 628  C CG    . LYS A 1 118 ? 109.308 139.120 134.427 1.00 212.67 ? 118 LYS A CG    1 
ATOM 629  C CD    . LYS A 1 118 ? 109.660 140.485 133.857 1.00 211.08 ? 118 LYS A CD    1 
ATOM 630  C CE    . LYS A 1 118 ? 110.220 141.403 134.932 1.00 213.83 ? 118 LYS A CE    1 
ATOM 631  N NZ    . LYS A 1 118 ? 110.471 142.776 134.415 1.00 211.99 ? 118 LYS A NZ    1 
ATOM 632  N N     . GLN A 1 119 ? 112.239 136.470 136.883 1.00 208.94 ? 119 GLN A N     1 
ATOM 633  C CA    . GLN A 1 119 ? 113.471 135.745 137.173 1.00 204.47 ? 119 GLN A CA    1 
ATOM 634  C C     . GLN A 1 119 ? 113.214 134.245 137.308 1.00 199.79 ? 119 GLN A C     1 
ATOM 635  O O     . GLN A 1 119 ? 114.020 133.430 136.847 1.00 194.42 ? 119 GLN A O     1 
ATOM 636  C CB    . GLN A 1 119 ? 114.112 136.316 138.438 1.00 206.60 ? 119 GLN A CB    1 
ATOM 637  C CG    . GLN A 1 119 ? 115.411 135.660 138.852 1.00 203.90 ? 119 GLN A CG    1 
ATOM 638  C CD    . GLN A 1 119 ? 116.266 136.572 139.709 1.00 204.48 ? 119 GLN A CD    1 
ATOM 639  O OE1   . GLN A 1 119 ? 117.382 136.931 139.333 1.00 202.11 ? 119 GLN A OE1   1 
ATOM 640  N NE2   . GLN A 1 119 ? 115.740 136.960 140.865 1.00 204.42 ? 119 GLN A NE2   1 
ATOM 641  N N     . TRP A 1 120 ? 112.084 133.859 137.912 1.00 202.38 ? 120 TRP A N     1 
ATOM 642  C CA    . TRP A 1 120 ? 111.753 132.438 138.009 1.00 198.22 ? 120 TRP A CA    1 
ATOM 643  C C     . TRP A 1 120 ? 111.398 131.843 136.652 1.00 192.31 ? 120 TRP A C     1 
ATOM 644  O O     . TRP A 1 120 ? 111.706 130.673 136.394 1.00 186.20 ? 120 TRP A O     1 
ATOM 645  C CB    . TRP A 1 120 ? 110.603 132.206 138.987 1.00 198.00 ? 120 TRP A CB    1 
ATOM 646  C CG    . TRP A 1 120 ? 110.408 130.747 139.297 1.00 199.02 ? 120 TRP A CG    1 
ATOM 647  C CD1   . TRP A 1 120 ? 111.031 130.028 140.276 1.00 200.47 ? 120 TRP A CD1   1 
ATOM 648  C CD2   . TRP A 1 120 ? 109.556 129.824 138.604 1.00 198.34 ? 120 TRP A CD2   1 
ATOM 649  N NE1   . TRP A 1 120 ? 110.611 128.720 140.244 1.00 200.54 ? 120 TRP A NE1   1 
ATOM 650  C CE2   . TRP A 1 120 ? 109.706 128.568 139.227 1.00 199.56 ? 120 TRP A CE2   1 
ATOM 651  C CE3   . TRP A 1 120 ? 108.678 129.940 137.522 1.00 195.43 ? 120 TRP A CE3   1 
ATOM 652  C CZ2   . TRP A 1 120 ? 109.010 127.437 138.805 1.00 196.94 ? 120 TRP A CZ2   1 
ATOM 653  C CZ3   . TRP A 1 120 ? 107.987 128.815 137.104 1.00 192.68 ? 120 TRP A CZ3   1 
ATOM 654  C CH2   . TRP A 1 120 ? 108.157 127.581 137.745 1.00 192.39 ? 120 TRP A CH2   1 
ATOM 655  N N     . GLU A 1 121 ? 110.740 132.616 135.785 1.00 194.08 ? 121 GLU A N     1 
ATOM 656  C CA    . GLU A 1 121 ? 110.504 132.152 134.421 1.00 189.22 ? 121 GLU A CA    1 
ATOM 657  C C     . GLU A 1 121 ? 111.820 131.977 133.674 1.00 183.21 ? 121 GLU A C     1 
ATOM 658  O O     . GLU A 1 121 ? 111.977 131.035 132.887 1.00 176.91 ? 121 GLU A O     1 
ATOM 659  C CB    . GLU A 1 121 ? 109.585 133.128 133.684 1.00 190.16 ? 121 GLU A CB    1 
ATOM 660  C CG    . GLU A 1 121 ? 109.187 132.695 132.274 1.00 187.79 ? 121 GLU A CG    1 
ATOM 661  C CD    . GLU A 1 121 ? 108.293 131.463 132.244 1.00 187.42 ? 121 GLU A CD    1 
ATOM 662  O OE1   . GLU A 1 121 ? 107.658 131.143 133.272 1.00 186.74 ? 121 GLU A OE1   1 
ATOM 663  O OE2   . GLU A 1 121 ? 108.225 130.810 131.181 1.00 188.10 ? 121 GLU A OE2   1 
ATOM 664  N N     . LYS A 1 122 ? 112.782 132.872 133.925 1.00 184.41 ? 122 LYS A N     1 
ATOM 665  C CA    . LYS A 1 122 ? 114.122 132.713 133.365 1.00 178.23 ? 122 LYS A CA    1 
ATOM 666  C C     . LYS A 1 122 ? 114.789 131.437 133.876 1.00 172.73 ? 122 LYS A C     1 
ATOM 667  O O     . LYS A 1 122 ? 115.437 130.723 133.106 1.00 165.46 ? 122 LYS A O     1 
ATOM 668  C CB    . LYS A 1 122 ? 114.973 133.942 133.695 1.00 177.30 ? 122 LYS A CB    1 
ATOM 669  C CG    . LYS A 1 122 ? 116.452 133.832 133.321 1.00 167.45 ? 122 LYS A CG    1 
ATOM 670  C CD    . LYS A 1 122 ? 116.650 133.505 131.845 1.00 160.29 ? 122 LYS A CD    1 
ATOM 671  C CE    . LYS A 1 122 ? 118.120 133.553 131.461 1.00 153.88 ? 122 LYS A CE    1 
ATOM 672  N NZ    . LYS A 1 122 ? 118.366 132.929 130.130 1.00 142.72 ? 122 LYS A NZ    1 
ATOM 673  N N     . GLU A 1 123 ? 114.640 131.137 135.172 1.00 177.01 ? 123 GLU A N     1 
ATOM 674  C CA    . GLU A 1 123 ? 115.205 129.900 135.716 1.00 172.53 ? 123 GLU A CA    1 
ATOM 675  C C     . GLU A 1 123 ? 114.553 128.666 135.103 1.00 162.80 ? 123 GLU A C     1 
ATOM 676  O O     . GLU A 1 123 ? 115.233 127.673 134.818 1.00 153.57 ? 123 GLU A O     1 
ATOM 677  C CB    . GLU A 1 123 ? 115.060 129.849 137.238 1.00 179.10 ? 123 GLU A CB    1 
ATOM 678  C CG    . GLU A 1 123 ? 115.717 130.972 138.008 1.00 181.43 ? 123 GLU A CG    1 
ATOM 679  C CD    . GLU A 1 123 ? 114.923 131.348 139.243 1.00 188.46 ? 123 GLU A CD    1 
ATOM 680  O OE1   . GLU A 1 123 ? 114.397 130.434 139.911 1.00 190.54 ? 123 GLU A OE1   1 
ATOM 681  O OE2   . GLU A 1 123 ? 114.824 132.552 139.549 1.00 191.47 ? 123 GLU A OE2   1 
ATOM 682  N N     . LYS A 1 124 ? 113.232 128.705 134.912 1.00 166.07 ? 124 LYS A N     1 
ATOM 683  C CA    . LYS A 1 124 ? 112.522 127.565 134.339 1.00 162.65 ? 124 LYS A CA    1 
ATOM 684  C C     . LYS A 1 124 ? 112.949 127.355 132.885 1.00 156.93 ? 124 LYS A C     1 
ATOM 685  O O     . LYS A 1 124 ? 113.195 126.219 132.459 1.00 150.16 ? 124 LYS A O     1 
ATOM 686  C CB    . LYS A 1 124 ? 111.007 127.806 134.467 1.00 169.31 ? 124 LYS A CB    1 
ATOM 687  C CG    . LYS A 1 124 ? 109.970 126.928 133.697 1.00 162.07 ? 124 LYS A CG    1 
ATOM 688  C CD    . LYS A 1 124 ? 110.286 125.432 133.501 1.00 153.94 ? 124 LYS A CD    1 
ATOM 689  C CE    . LYS A 1 124 ? 110.411 124.687 134.827 1.00 150.97 ? 124 LYS A CE    1 
ATOM 690  N NZ    . LYS A 1 124 ? 110.552 123.217 134.638 1.00 146.33 ? 124 LYS A NZ    1 
ATOM 691  N N     . GLN A 1 125 ? 113.076 128.447 132.124 1.00 158.72 ? 125 GLN A N     1 
ATOM 692  C CA    . GLN A 1 125 ? 113.546 128.354 130.744 1.00 152.54 ? 125 GLN A CA    1 
ATOM 693  C C     . GLN A 1 125 ? 114.995 127.880 130.678 1.00 145.77 ? 125 GLN A C     1 
ATOM 694  O O     . GLN A 1 125 ? 115.366 127.131 129.769 1.00 139.14 ? 125 GLN A O     1 
ATOM 695  C CB    . GLN A 1 125 ? 113.384 129.708 130.050 1.00 154.36 ? 125 GLN A CB    1 
ATOM 696  C CG    . GLN A 1 125 ? 113.861 129.747 128.607 1.00 153.09 ? 125 GLN A CG    1 
ATOM 697  C CD    . GLN A 1 125 ? 113.779 131.136 128.007 1.00 153.70 ? 125 GLN A CD    1 
ATOM 698  O OE1   . GLN A 1 125 ? 113.054 131.997 128.503 1.00 154.06 ? 125 GLN A OE1   1 
ATOM 699  N NE2   . GLN A 1 125 ? 114.523 131.359 126.930 1.00 153.99 ? 125 GLN A NE2   1 
ATOM 700  N N     . GLU A 1 126 ? 115.827 128.312 131.632 1.00 147.19 ? 126 GLU A N     1 
ATOM 701  C CA    . GLU A 1 126 ? 117.206 127.840 131.700 1.00 141.62 ? 126 GLU A CA    1 
ATOM 702  C C     . GLU A 1 126 ? 117.267 126.346 131.984 1.00 134.90 ? 126 GLU A C     1 
ATOM 703  O O     . GLU A 1 126 ? 118.069 125.627 131.381 1.00 128.02 ? 126 GLU A O     1 
ATOM 704  C CB    . GLU A 1 126 ? 117.971 128.620 132.771 1.00 140.40 ? 126 GLU A CB    1 
ATOM 705  C CG    . GLU A 1 126 ? 119.481 128.402 132.776 1.00 130.68 ? 126 GLU A CG    1 
ATOM 706  C CD    . GLU A 1 126 ? 120.231 129.312 131.817 1.00 124.72 ? 126 GLU A CD    1 
ATOM 707  O OE1   . GLU A 1 126 ? 119.610 129.856 130.879 1.00 129.10 ? 126 GLU A OE1   1 
ATOM 708  O OE2   . GLU A 1 126 ? 121.454 129.486 132.005 1.00 116.03 ? 126 GLU A OE2   1 
ATOM 709  N N     . TRP A 1 127 ? 116.429 125.864 132.906 1.00 137.82 ? 127 TRP A N     1 
ATOM 710  C CA    . TRP A 1 127 ? 116.374 124.433 133.189 1.00 131.41 ? 127 TRP A CA    1 
ATOM 711  C C     . TRP A 1 127 ? 115.905 123.643 131.975 1.00 126.64 ? 127 TRP A C     1 
ATOM 712  O O     . TRP A 1 127 ? 116.450 122.576 131.675 1.00 121.56 ? 127 TRP A O     1 
ATOM 713  C CB    . TRP A 1 127 ? 115.455 124.158 134.377 1.00 131.57 ? 127 TRP A CB    1 
ATOM 714  C CG    . TRP A 1 127 ? 115.725 122.838 135.025 1.00 129.79 ? 127 TRP A CG    1 
ATOM 715  C CD1   . TRP A 1 127 ? 116.918 122.176 135.070 1.00 120.07 ? 127 TRP A CD1   1 
ATOM 716  C CD2   . TRP A 1 127 ? 114.771 121.992 135.675 1.00 133.00 ? 127 TRP A CD2   1 
ATOM 717  N NE1   . TRP A 1 127 ? 116.771 120.982 135.733 1.00 120.30 ? 127 TRP A NE1   1 
ATOM 718  C CE2   . TRP A 1 127 ? 115.461 120.843 136.111 1.00 130.12 ? 127 TRP A CE2   1 
ATOM 719  C CE3   . TRP A 1 127 ? 113.403 122.098 135.941 1.00 134.42 ? 127 TRP A CE3   1 
ATOM 720  C CZ2   . TRP A 1 127 ? 114.829 119.809 136.799 1.00 132.20 ? 127 TRP A CZ2   1 
ATOM 721  C CZ3   . TRP A 1 127 ? 112.777 121.071 136.624 1.00 134.53 ? 127 TRP A CZ3   1 
ATOM 722  C CH2   . TRP A 1 127 ? 113.490 119.942 137.045 1.00 133.58 ? 127 TRP A CH2   1 
ATOM 723  N N     . GLU A 1 128 ? 114.891 124.148 131.269 1.00 130.52 ? 128 GLU A N     1 
ATOM 724  C CA    . GLU A 1 128 ? 114.395 123.447 130.089 1.00 127.87 ? 128 GLU A CA    1 
ATOM 725  C C     . GLU A 1 128 ? 115.425 123.441 128.966 1.00 121.64 ? 128 GLU A C     1 
ATOM 726  O O     . GLU A 1 128 ? 115.558 122.445 128.246 1.00 117.46 ? 128 GLU A O     1 
ATOM 727  C CB    . GLU A 1 128 ? 113.082 124.079 129.611 1.00 134.96 ? 128 GLU A CB    1 
ATOM 728  C CG    . GLU A 1 128 ? 111.812 123.906 130.493 1.00 138.76 ? 128 GLU A CG    1 
ATOM 729  C CD    . GLU A 1 128 ? 111.493 122.493 131.025 1.00 138.76 ? 128 GLU A CD    1 
ATOM 730  O OE1   . GLU A 1 128 ? 112.084 121.472 130.608 1.00 136.23 ? 128 GLU A OE1   1 
ATOM 731  O OE2   . GLU A 1 128 ? 110.605 122.410 131.898 1.00 142.33 ? 128 GLU A OE2   1 
ATOM 732  N N     . GLU A 1 129 ? 116.166 124.539 128.806 1.00 121.70 ? 129 GLU A N     1 
ATOM 733  C CA    . GLU A 1 129 ? 117.133 124.628 127.717 1.00 118.32 ? 129 GLU A CA    1 
ATOM 734  C C     . GLU A 1 129 ? 118.354 123.758 127.984 1.00 112.02 ? 129 GLU A C     1 
ATOM 735  O O     . GLU A 1 129 ? 118.922 123.176 127.053 1.00 103.58 ? 129 GLU A O     1 
ATOM 736  C CB    . GLU A 1 129 ? 117.549 126.083 127.505 1.00 119.23 ? 129 GLU A CB    1 
ATOM 737  N N     . THR A 1 130 ? 118.779 123.663 129.246 1.00 111.65 ? 130 THR A N     1 
ATOM 738  C CA    . THR A 1 130 ? 119.937 122.836 129.567 1.00 100.04 ? 130 THR A CA    1 
ATOM 739  C C     . THR A 1 130 ? 119.617 121.354 129.443 1.00 93.51  ? 130 THR A C     1 
ATOM 740  O O     . THR A 1 130 ? 120.416 120.595 128.886 1.00 86.65  ? 130 THR A O     1 
ATOM 741  C CB    . THR A 1 130 ? 120.448 123.149 130.971 1.00 97.00  ? 130 THR A CB    1 
ATOM 742  O OG1   . THR A 1 130 ? 119.366 123.068 131.907 1.00 109.77 ? 130 THR A OG1   1 
ATOM 743  C CG2   . THR A 1 130 ? 121.073 124.528 131.015 1.00 89.23  ? 130 THR A CG2   1 
ATOM 744  N N     . LYS A 1 131 ? 118.440 120.932 129.919 1.00 96.35  ? 131 LYS A N     1 
ATOM 745  C CA    . LYS A 1 131 ? 118.099 119.512 129.975 1.00 90.86  ? 131 LYS A CA    1 
ATOM 746  C C     . LYS A 1 131 ? 118.023 118.859 128.600 1.00 87.87  ? 131 LYS A C     1 
ATOM 747  O O     . LYS A 1 131 ? 118.150 117.633 128.506 1.00 85.72  ? 131 LYS A O     1 
ATOM 748  C CB    . LYS A 1 131 ? 116.768 119.313 130.700 1.00 97.37  ? 131 LYS A CB    1 
ATOM 749  C CG    . LYS A 1 131 ? 116.861 119.410 132.210 1.00 100.59 ? 131 LYS A CG    1 
ATOM 750  C CD    . LYS A 1 131 ? 115.555 119.007 132.879 1.00 109.62 ? 131 LYS A CD    1 
ATOM 751  C CE    . LYS A 1 131 ? 114.400 119.870 132.405 1.00 120.07 ? 131 LYS A CE    1 
ATOM 752  N NZ    . LYS A 1 131 ? 113.110 119.451 133.013 1.00 125.71 ? 131 LYS A NZ    1 
ATOM 753  N N     . ARG A 1 132 ? 117.812 119.643 127.540 1.00 90.66  ? 132 ARG A N     1 
ATOM 754  C CA    . ARG A 1 132 ? 117.872 119.102 126.189 1.00 90.80  ? 132 ARG A CA    1 
ATOM 755  C C     . ARG A 1 132 ? 119.294 118.755 125.774 1.00 88.82  ? 132 ARG A C     1 
ATOM 756  O O     . ARG A 1 132 ? 119.482 117.872 124.930 1.00 90.41  ? 132 ARG A O     1 
ATOM 757  C CB    . ARG A 1 132 ? 117.273 120.098 125.195 1.00 89.78  ? 132 ARG A CB    1 
ATOM 758  N N     . ASN A 1 133 ? 120.296 119.424 126.350 1.00 82.33  ? 133 ASN A N     1 
ATOM 759  C CA    . ASN A 1 133 ? 121.690 119.129 126.061 1.00 76.20  ? 133 ASN A CA    1 
ATOM 760  C C     . ASN A 1 133 ? 122.461 118.605 127.257 1.00 75.76  ? 133 ASN A C     1 
ATOM 761  O O     . ASN A 1 133 ? 123.447 117.888 127.060 1.00 72.82  ? 133 ASN A O     1 
ATOM 762  C CB    . ASN A 1 133 ? 122.417 120.371 125.526 1.00 72.15  ? 133 ASN A CB    1 
ATOM 763  C CG    . ASN A 1 133 ? 121.602 121.133 124.515 1.00 78.19  ? 133 ASN A CG    1 
ATOM 764  O OD1   . ASN A 1 133 ? 121.411 122.341 124.643 1.00 76.69  ? 133 ASN A OD1   1 
ATOM 765  N ND2   . ASN A 1 133 ? 121.116 120.435 123.499 1.00 88.21  ? 133 ASN A ND2   1 
ATOM 766  N N     . SER A 1 134 ? 122.050 118.926 128.479 1.00 77.66  ? 134 SER A N     1 
ATOM 767  C CA    . SER A 1 134 ? 122.673 118.326 129.645 1.00 66.94  ? 134 SER A CA    1 
ATOM 768  C C     . SER A 1 134 ? 122.036 116.976 129.949 1.00 64.32  ? 134 SER A C     1 
ATOM 769  O O     . SER A 1 134 ? 120.845 116.752 129.707 1.00 70.02  ? 134 SER A O     1 
ATOM 770  C CB    . SER A 1 134 ? 122.545 119.241 130.864 1.00 63.53  ? 134 SER A CB    1 
ATOM 771  O OG    . SER A 1 134 ? 122.903 120.579 130.560 1.00 66.46  ? 134 SER A OG    1 
ATOM 772  N N     . ARG A 1 135 ? 122.844 116.076 130.498 1.00 58.78  ? 135 ARG A N     1 
ATOM 773  C CA    . ARG A 1 135 ? 122.364 114.829 131.062 1.00 60.41  ? 135 ARG A CA    1 
ATOM 774  C C     . ARG A 1 135 ? 122.530 114.919 132.566 1.00 61.84  ? 135 ARG A C     1 
ATOM 775  O O     . ARG A 1 135 ? 123.406 115.628 133.060 1.00 64.52  ? 135 ARG A O     1 
ATOM 776  C CB    . ARG A 1 135 ? 123.131 113.622 130.537 1.00 54.43  ? 135 ARG A CB    1 
ATOM 777  C CG    . ARG A 1 135 ? 123.549 113.730 129.089 1.00 49.98  ? 135 ARG A CG    1 
ATOM 778  C CD    . ARG A 1 135 ? 124.752 112.835 128.770 1.00 49.90  ? 135 ARG A CD    1 
ATOM 779  N NE    . ARG A 1 135 ? 124.417 111.416 128.674 1.00 54.75  ? 135 ARG A NE    1 
ATOM 780  C CZ    . ARG A 1 135 ? 125.252 110.460 128.281 1.00 55.08  ? 135 ARG A CZ    1 
ATOM 781  N NH1   . ARG A 1 135 ? 126.505 110.725 127.950 1.00 45.49  ? 135 ARG A NH1   1 
ATOM 782  N NH2   . ARG A 1 135 ? 124.819 109.204 128.224 1.00 60.59  ? 135 ARG A NH2   1 
ATOM 783  N N     . HIS A 1 136 ? 121.676 114.214 133.295 1.00 59.61  ? 136 HIS A N     1 
ATOM 784  C CA    . HIS A 1 136 ? 121.919 114.103 134.718 1.00 59.15  ? 136 HIS A CA    1 
ATOM 785  C C     . HIS A 1 136 ? 123.144 113.227 134.927 1.00 57.16  ? 136 HIS A C     1 
ATOM 786  O O     . HIS A 1 136 ? 123.417 112.314 134.140 1.00 55.04  ? 136 HIS A O     1 
ATOM 787  C CB    . HIS A 1 136 ? 120.690 113.540 135.423 1.00 66.29  ? 136 HIS A CB    1 
ATOM 788  C CG    . HIS A 1 136 ? 120.850 113.403 136.902 1.00 70.22  ? 136 HIS A CG    1 
ATOM 789  N ND1   . HIS A 1 136 ? 121.357 112.265 137.491 1.00 68.30  ? 136 HIS A ND1   1 
ATOM 790  C CD2   . HIS A 1 136 ? 120.588 114.262 137.913 1.00 75.96  ? 136 HIS A CD2   1 
ATOM 791  C CE1   . HIS A 1 136 ? 121.390 112.423 138.801 1.00 72.00  ? 136 HIS A CE1   1 
ATOM 792  N NE2   . HIS A 1 136 ? 120.931 113.628 139.083 1.00 79.17  ? 136 HIS A NE2   1 
ATOM 793  N N     . ARG A 1 137 ? 123.902 113.529 135.986 1.00 58.80  ? 137 ARG A N     1 
ATOM 794  C CA    . ARG A 1 137 ? 125.222 112.929 136.142 1.00 58.34  ? 137 ARG A CA    1 
ATOM 795  C C     . ARG A 1 137 ? 125.174 111.425 136.335 1.00 61.51  ? 137 ARG A C     1 
ATOM 796  O O     . ARG A 1 137 ? 126.087 110.748 135.854 1.00 60.76  ? 137 ARG A O     1 
ATOM 797  C CB    . ARG A 1 137 ? 125.960 113.565 137.323 1.00 51.28  ? 137 ARG A CB    1 
ATOM 798  C CG    . ARG A 1 137 ? 127.387 113.066 137.554 1.00 42.59  ? 137 ARG A CG    1 
ATOM 799  C CD    . ARG A 1 137 ? 128.419 114.158 137.601 1.00 43.44  ? 137 ARG A CD    1 
ATOM 800  N NE    . ARG A 1 137 ? 128.106 115.186 138.583 1.00 46.94  ? 137 ARG A NE    1 
ATOM 801  C CZ    . ARG A 1 137 ? 128.088 116.483 138.318 1.00 49.86  ? 137 ARG A CZ    1 
ATOM 802  N NH1   . ARG A 1 137 ? 128.417 116.946 137.125 1.00 51.20  ? 137 ARG A NH1   1 
ATOM 803  N NH2   . ARG A 1 137 ? 127.742 117.337 139.275 1.00 57.27  ? 137 ARG A NH2   1 
ATOM 804  N N     . LYS A 1 138 ? 124.087 110.879 136.894 1.00 64.46  ? 138 LYS A N     1 
ATOM 805  C CA    . LYS A 1 138 ? 123.998 109.439 137.115 1.00 63.23  ? 138 LYS A CA    1 
ATOM 806  C C     . LYS A 1 138 ? 123.942 108.684 135.794 1.00 63.83  ? 138 LYS A C     1 
ATOM 807  O O     . LYS A 1 138 ? 124.317 107.508 135.729 1.00 66.84  ? 138 LYS A O     1 
ATOM 808  C CB    . LYS A 1 138 ? 122.778 109.109 137.975 1.00 59.29  ? 138 LYS A CB    1 
ATOM 809  N N     . GLU A 1 139 ? 123.464 109.343 134.738 1.00 59.26  ? 139 GLU A N     1 
ATOM 810  C CA    . GLU A 1 139 ? 123.619 108.795 133.397 1.00 57.62  ? 139 GLU A CA    1 
ATOM 811  C C     . GLU A 1 139 ? 125.082 108.807 132.969 1.00 62.43  ? 139 GLU A C     1 
ATOM 812  O O     . GLU A 1 139 ? 125.608 107.787 132.515 1.00 62.72  ? 139 GLU A O     1 
ATOM 813  C CB    . GLU A 1 139 ? 122.756 109.576 132.408 1.00 56.75  ? 139 GLU A CB    1 
ATOM 814  N N     . VAL A 1 140 ? 125.760 109.950 133.136 1.00 63.10  ? 140 VAL A N     1 
ATOM 815  C CA    . VAL A 1 140 ? 127.158 110.078 132.719 1.00 58.85  ? 140 VAL A CA    1 
ATOM 816  C C     . VAL A 1 140 ? 128.037 109.114 133.503 1.00 62.74  ? 140 VAL A C     1 
ATOM 817  O O     . VAL A 1 140 ? 128.970 108.511 132.955 1.00 63.81  ? 140 VAL A O     1 
ATOM 818  C CB    . VAL A 1 140 ? 127.633 111.535 132.877 1.00 48.02  ? 140 VAL A CB    1 
ATOM 819  C CG1   . VAL A 1 140 ? 129.030 111.709 132.310 1.00 42.03  ? 140 VAL A CG1   1 
ATOM 820  C CG2   . VAL A 1 140 ? 126.662 112.488 132.207 1.00 49.45  ? 140 VAL A CG2   1 
ATOM 821  N N     . VAL A 1 141 ? 127.722 108.926 134.788 1.00 63.86  ? 141 VAL A N     1 
ATOM 822  C CA    . VAL A 1 141 ? 128.352 107.878 135.587 1.00 65.62  ? 141 VAL A CA    1 
ATOM 823  C C     . VAL A 1 141 ? 128.102 106.507 134.967 1.00 70.02  ? 141 VAL A C     1 
ATOM 824  O O     . VAL A 1 141 ? 128.982 105.640 134.977 1.00 71.36  ? 141 VAL A O     1 
ATOM 825  C CB    . VAL A 1 141 ? 127.848 107.952 137.043 1.00 64.47  ? 141 VAL A CB    1 
ATOM 826  C CG1   . VAL A 1 141 ? 128.437 106.841 137.897 1.00 67.58  ? 141 VAL A CG1   1 
ATOM 827  C CG2   . VAL A 1 141 ? 128.207 109.291 137.645 1.00 59.52  ? 141 VAL A CG2   1 
ATOM 828  N N     . LYS A 1 142 ? 126.914 106.296 134.392 1.00 67.65  ? 142 LYS A N     1 
ATOM 829  C CA    . LYS A 1 142 ? 126.619 104.997 133.793 1.00 69.89  ? 142 LYS A CA    1 
ATOM 830  C C     . LYS A 1 142 ? 127.436 104.754 132.524 1.00 72.36  ? 142 LYS A C     1 
ATOM 831  O O     . LYS A 1 142 ? 127.919 103.635 132.310 1.00 75.12  ? 142 LYS A O     1 
ATOM 832  C CB    . LYS A 1 142 ? 125.122 104.860 133.518 1.00 70.25  ? 142 LYS A CB    1 
ATOM 833  C CG    . LYS A 1 142 ? 124.633 103.427 133.431 1.00 75.29  ? 142 LYS A CG    1 
ATOM 834  C CD    . LYS A 1 142 ? 123.198 103.367 132.932 1.00 78.32  ? 142 LYS A CD    1 
ATOM 835  C CE    . LYS A 1 142 ? 122.279 104.251 133.761 1.00 77.38  ? 142 LYS A CE    1 
ATOM 836  N NZ    . LYS A 1 142 ? 122.125 103.735 135.148 1.00 76.48  ? 142 LYS A NZ    1 
ATOM 837  N N     . ASP A 1 143 ? 127.623 105.775 131.669 1.00 69.74  ? 143 ASP A N     1 
ATOM 838  C CA    . ASP A 1 143 ? 128.504 105.546 130.518 1.00 72.58  ? 143 ASP A CA    1 
ATOM 839  C C     . ASP A 1 143 ? 129.960 105.392 130.944 1.00 72.79  ? 143 ASP A C     1 
ATOM 840  O O     . ASP A 1 143 ? 130.708 104.626 130.322 1.00 76.35  ? 143 ASP A O     1 
ATOM 841  C CB    . ASP A 1 143 ? 128.406 106.630 129.432 1.00 70.09  ? 143 ASP A CB    1 
ATOM 842  C CG    . ASP A 1 143 ? 126.996 107.112 129.163 1.00 72.27  ? 143 ASP A CG    1 
ATOM 843  O OD1   . ASP A 1 143 ? 126.441 107.862 129.974 1.00 68.50  ? 143 ASP A OD1   1 
ATOM 844  O OD2   . ASP A 1 143 ? 126.431 106.732 128.114 1.00 74.95  ? 143 ASP A OD2   1 
ATOM 845  N N     . VAL A 1 144 ? 130.386 106.108 131.992 1.00 70.90  ? 144 VAL A N     1 
ATOM 846  C CA    . VAL A 1 144 ? 131.741 105.918 132.512 1.00 67.90  ? 144 VAL A CA    1 
ATOM 847  C C     . VAL A 1 144 ? 131.922 104.492 133.020 1.00 74.27  ? 144 VAL A C     1 
ATOM 848  O O     . VAL A 1 144 ? 132.943 103.844 132.749 1.00 74.95  ? 144 VAL A O     1 
ATOM 849  C CB    . VAL A 1 144 ? 132.054 106.960 133.603 1.00 58.26  ? 144 VAL A CB    1 
ATOM 850  C CG1   . VAL A 1 144 ? 133.349 106.621 134.309 1.00 58.96  ? 144 VAL A CG1   1 
ATOM 851  C CG2   . VAL A 1 144 ? 132.184 108.336 132.987 1.00 50.00  ? 144 VAL A CG2   1 
ATOM 852  N N     . HIS A 1 145 ? 130.918 103.973 133.734 1.00 74.85  ? 145 HIS A N     1 
ATOM 853  C CA    . HIS A 1 145 ? 130.964 102.597 134.218 1.00 77.17  ? 145 HIS A CA    1 
ATOM 854  C C     . HIS A 1 145 ? 131.002 101.603 133.068 1.00 80.50  ? 145 HIS A C     1 
ATOM 855  O O     . HIS A 1 145 ? 131.766 100.634 133.109 1.00 83.04  ? 145 HIS A O     1 
ATOM 856  C CB    . HIS A 1 145 ? 129.762 102.310 135.117 1.00 76.74  ? 145 HIS A CB    1 
ATOM 857  C CG    . HIS A 1 145 ? 129.853 102.940 136.470 1.00 77.38  ? 145 HIS A CG    1 
ATOM 858  N ND1   . HIS A 1 145 ? 128.981 102.636 137.493 1.00 77.71  ? 145 HIS A ND1   1 
ATOM 859  C CD2   . HIS A 1 145 ? 130.708 103.864 136.967 1.00 76.66  ? 145 HIS A CD2   1 
ATOM 860  C CE1   . HIS A 1 145 ? 129.301 103.338 138.565 1.00 76.98  ? 145 HIS A CE1   1 
ATOM 861  N NE2   . HIS A 1 145 ? 130.347 104.090 138.273 1.00 77.29  ? 145 HIS A NE2   1 
ATOM 862  N N     . LYS A 1 146 ? 130.188 101.831 132.033 1.00 78.53  ? 146 LYS A N     1 
ATOM 863  C CA    . LYS A 1 146 ? 130.171 100.941 130.874 1.00 80.25  ? 146 LYS A CA    1 
ATOM 864  C C     . LYS A 1 146 ? 131.529 100.912 130.183 1.00 84.04  ? 146 LYS A C     1 
ATOM 865  O O     . LYS A 1 146 ? 132.066 99.835  129.885 1.00 88.90  ? 146 LYS A O     1 
ATOM 866  C CB    . LYS A 1 146 ? 129.083 101.387 129.898 1.00 80.62  ? 146 LYS A CB    1 
ATOM 867  C CG    . LYS A 1 146 ? 129.007 100.562 128.625 1.00 90.82  ? 146 LYS A CG    1 
ATOM 868  C CD    . LYS A 1 146 ? 127.897 101.059 127.713 1.00 98.71  ? 146 LYS A CD    1 
ATOM 869  C CE    . LYS A 1 146 ? 126.526 100.771 128.301 1.00 104.72 ? 146 LYS A CE    1 
ATOM 870  N NZ    . LYS A 1 146 ? 126.216 99.315  128.294 1.00 104.08 ? 146 LYS A NZ    1 
ATOM 871  N N     . ALA A 1 147 ? 132.115 102.092 129.960 1.00 83.47  ? 147 ALA A N     1 
ATOM 872  C CA    . ALA A 1 147 ? 133.411 102.173 129.295 1.00 84.89  ? 147 ALA A CA    1 
ATOM 873  C C     . ALA A 1 147 ? 134.510 101.528 130.129 1.00 86.89  ? 147 ALA A C     1 
ATOM 874  O O     . ALA A 1 147 ? 135.359 100.810 129.591 1.00 90.18  ? 147 ALA A O     1 
ATOM 875  C CB    . ALA A 1 147 ? 133.751 103.631 128.993 1.00 77.59  ? 147 ALA A CB    1 
ATOM 876  N N     . MET A 1 148 ? 134.502 101.749 131.445 1.00 82.94  ? 148 MET A N     1 
ATOM 877  C CA    . MET A 1 148 ? 135.581 101.222 132.270 1.00 81.99  ? 148 MET A CA    1 
ATOM 878  C C     . MET A 1 148 ? 135.437 99.723  132.512 1.00 85.27  ? 148 MET A C     1 
ATOM 879  O O     . MET A 1 148 ? 136.447 99.033  132.688 1.00 87.31  ? 148 MET A O     1 
ATOM 880  C CB    . MET A 1 148 ? 135.648 101.985 133.592 1.00 80.54  ? 148 MET A CB    1 
ATOM 881  C CG    . MET A 1 148 ? 136.328 103.342 133.456 1.00 75.62  ? 148 MET A CG    1 
ATOM 882  S SD    . MET A 1 148 ? 138.089 103.360 133.838 1.00 81.74  ? 148 MET A SD    1 
ATOM 883  C CE    . MET A 1 148 ? 138.079 102.884 135.558 1.00 81.78  ? 148 MET A CE    1 
ATOM 884  N N     . ILE A 1 149 ? 134.206 99.203  132.531 1.00 85.52  ? 149 ILE A N     1 
ATOM 885  C CA    . ILE A 1 149 ? 134.010 97.757  132.590 1.00 87.89  ? 149 ILE A CA    1 
ATOM 886  C C     . ILE A 1 149 ? 134.446 97.106  131.281 1.00 89.81  ? 149 ILE A C     1 
ATOM 887  O O     . ILE A 1 149 ? 135.036 96.017  131.283 1.00 92.05  ? 149 ILE A O     1 
ATOM 888  C CB    . ILE A 1 149 ? 132.547 97.435  132.955 1.00 87.17  ? 149 ILE A CB    1 
ATOM 889  C CG1   . ILE A 1 149 ? 132.282 97.778  134.424 1.00 85.00  ? 149 ILE A CG1   1 
ATOM 890  C CG2   . ILE A 1 149 ? 132.194 95.975  132.687 1.00 90.35  ? 149 ILE A CG2   1 
ATOM 891  C CD1   . ILE A 1 149 ? 132.989 96.866  135.405 1.00 89.09  ? 149 ILE A CD1   1 
ATOM 892  N N     . GLU A 1 150 ? 134.196 97.775  130.146 1.00 89.47  ? 150 GLU A N     1 
ATOM 893  C CA    . GLU A 1 150 ? 134.690 97.264  128.867 1.00 92.24  ? 150 GLU A CA    1 
ATOM 894  C C     . GLU A 1 150 ? 136.214 97.198  128.819 1.00 93.57  ? 150 GLU A C     1 
ATOM 895  O O     . GLU A 1 150 ? 136.774 96.389  128.071 1.00 95.57  ? 150 GLU A O     1 
ATOM 896  C CB    . GLU A 1 150 ? 134.170 98.119  127.710 1.00 94.15  ? 150 GLU A CB    1 
ATOM 897  C CG    . GLU A 1 150 ? 132.709 97.896  127.363 1.00 97.11  ? 150 GLU A CG    1 
ATOM 898  C CD    . GLU A 1 150 ? 132.302 98.617  126.092 1.00 102.57 ? 150 GLU A CD    1 
ATOM 899  O OE1   . GLU A 1 150 ? 132.849 99.707  125.824 1.00 103.85 ? 150 GLU A OE1   1 
ATOM 900  O OE2   . GLU A 1 150 ? 131.438 98.092  125.359 1.00 104.51 ? 150 GLU A OE2   1 
ATOM 901  N N     . GLY A 1 151 ? 136.898 98.029  129.600 1.00 92.48  ? 151 GLY A N     1 
ATOM 902  C CA    . GLY A 1 151 ? 138.346 97.997  129.655 1.00 91.75  ? 151 GLY A CA    1 
ATOM 903  C C     . GLY A 1 151 ? 138.900 97.189  130.809 1.00 94.02  ? 151 GLY A C     1 
ATOM 904  O O     . GLY A 1 151 ? 140.065 97.365  131.179 1.00 91.17  ? 151 GLY A O     1 
ATOM 905  N N     . ARG A 1 152 ? 138.053 96.316  131.375 1.00 96.03  ? 152 ARG A N     1 
ATOM 906  C CA    . ARG A 1 152 ? 138.370 95.365  132.462 1.00 99.11  ? 152 ARG A CA    1 
ATOM 907  C C     . ARG A 1 152 ? 139.159 96.005  133.609 1.00 99.33  ? 152 ARG A C     1 
ATOM 908  O O     . ARG A 1 152 ? 140.073 95.408  134.181 1.00 100.74 ? 152 ARG A O     1 
ATOM 909  C CB    . ARG A 1 152 ? 139.066 94.097  131.927 1.00 100.69 ? 152 ARG A CB    1 
ATOM 910  C CG    . ARG A 1 152 ? 140.450 94.223  131.269 1.00 101.83 ? 152 ARG A CG    1 
ATOM 911  C CD    . ARG A 1 152 ? 140.841 93.061  130.337 1.00 105.06 ? 152 ARG A CD    1 
ATOM 912  N NE    . ARG A 1 152 ? 139.956 92.863  129.191 1.00 107.09 ? 152 ARG A NE    1 
ATOM 913  C CZ    . ARG A 1 152 ? 138.881 92.085  129.175 1.00 109.58 ? 152 ARG A CZ    1 
ATOM 914  N NH1   . ARG A 1 152 ? 138.547 91.341  130.217 1.00 112.54 ? 152 ARG A NH1   1 
ATOM 915  N NH2   . ARG A 1 152 ? 138.134 92.035  128.076 1.00 107.83 ? 152 ARG A NH2   1 
ATOM 916  N N     . ALA A 1 153 ? 138.774 97.223  133.974 1.00 95.86  ? 153 ALA A N     1 
ATOM 917  C CA    . ALA A 1 153 ? 139.404 97.925  135.079 1.00 93.32  ? 153 ALA A CA    1 
ATOM 918  C C     . ALA A 1 153 ? 138.779 97.506  136.409 1.00 97.47  ? 153 ALA A C     1 
ATOM 919  O O     . ALA A 1 153 ? 137.757 96.819  136.458 1.00 100.41 ? 153 ALA A O     1 
ATOM 920  C CB    . ALA A 1 153 ? 139.293 99.435  134.883 1.00 90.87  ? 153 ALA A CB    1 
ATOM 921  N N     . THR A 1 154 ? 139.410 97.932  137.499 1.00 95.70  ? 154 THR A N     1 
ATOM 922  C CA    . THR A 1 154 ? 138.968 97.565  138.836 1.00 93.12  ? 154 THR A CA    1 
ATOM 923  C C     . THR A 1 154 ? 137.943 98.563  139.366 1.00 89.63  ? 154 THR A C     1 
ATOM 924  O O     . THR A 1 154 ? 137.785 99.669  138.846 1.00 89.29  ? 154 THR A O     1 
ATOM 925  C CB    . THR A 1 154 ? 140.153 97.487  139.799 1.00 88.74  ? 154 THR A CB    1 
ATOM 926  O OG1   . THR A 1 154 ? 140.738 98.786  139.944 1.00 85.60  ? 154 THR A OG1   1 
ATOM 927  C CG2   . THR A 1 154 ? 141.202 96.521  139.271 1.00 87.08  ? 154 THR A CG2   1 
ATOM 928  N N     . GLU A 1 155 ? 137.244 98.148  140.426 1.00 86.66  ? 155 GLU A N     1 
ATOM 929  C CA    . GLU A 1 155 ? 136.218 98.994  141.029 1.00 88.49  ? 155 GLU A CA    1 
ATOM 930  C C     . GLU A 1 155 ? 136.825 100.201 141.736 1.00 86.39  ? 155 GLU A C     1 
ATOM 931  O O     . GLU A 1 155 ? 136.209 101.273 141.765 1.00 86.10  ? 155 GLU A O     1 
ATOM 932  C CB    . GLU A 1 155 ? 135.372 98.166  142.002 1.00 94.16  ? 155 GLU A CB    1 
ATOM 933  C CG    . GLU A 1 155 ? 134.249 98.921  142.714 1.00 94.15  ? 155 GLU A CG    1 
ATOM 934  C CD    . GLU A 1 155 ? 133.159 99.423  141.778 1.00 95.44  ? 155 GLU A CD    1 
ATOM 935  O OE1   . GLU A 1 155 ? 133.021 98.889  140.656 1.00 97.19  ? 155 GLU A OE1   1 
ATOM 936  O OE2   . GLU A 1 155 ? 132.434 100.361 142.169 1.00 96.47  ? 155 GLU A OE2   1 
ATOM 937  N N     . GLU A 1 156 ? 138.022 100.044 142.309 1.00 85.41  ? 156 GLU A N     1 
ATOM 938  C CA    . GLU A 1 156 ? 138.700 101.168 142.949 1.00 85.33  ? 156 GLU A CA    1 
ATOM 939  C C     . GLU A 1 156 ? 139.033 102.253 141.931 1.00 81.49  ? 156 GLU A C     1 
ATOM 940  O O     . GLU A 1 156 ? 138.868 103.447 142.208 1.00 80.42  ? 156 GLU A O     1 
ATOM 941  C CB    . GLU A 1 156 ? 139.964 100.669 143.661 1.00 88.73  ? 156 GLU A CB    1 
ATOM 942  C CG    . GLU A 1 156 ? 141.145 101.653 143.823 1.00 90.99  ? 156 GLU A CG    1 
ATOM 943  C CD    . GLU A 1 156 ? 140.830 102.952 144.571 1.00 94.35  ? 156 GLU A CD    1 
ATOM 944  O OE1   . GLU A 1 156 ? 139.788 103.048 145.255 1.00 97.63  ? 156 GLU A OE1   1 
ATOM 945  O OE2   . GLU A 1 156 ? 141.647 103.892 144.472 1.00 90.63  ? 156 GLU A OE2   1 
ATOM 946  N N     . GLN A 1 157 ? 139.480 101.851 140.738 1.00 79.75  ? 157 GLN A N     1 
ATOM 947  C CA    . GLN A 1 157 ? 139.737 102.818 139.675 1.00 77.28  ? 157 GLN A CA    1 
ATOM 948  C C     . GLN A 1 157 ? 138.452 103.509 139.236 1.00 74.67  ? 157 GLN A C     1 
ATOM 949  O O     . GLN A 1 157 ? 138.454 104.712 138.950 1.00 73.81  ? 157 GLN A O     1 
ATOM 950  C CB    . GLN A 1 157 ? 140.407 102.127 138.489 1.00 78.18  ? 157 GLN A CB    1 
ATOM 951  C CG    . GLN A 1 157 ? 141.850 101.728 138.741 1.00 80.01  ? 157 GLN A CG    1 
ATOM 952  C CD    . GLN A 1 157 ? 142.297 100.573 137.868 1.00 83.30  ? 157 GLN A CD    1 
ATOM 953  O OE1   . GLN A 1 157 ? 141.525 99.657  137.589 1.00 85.89  ? 157 GLN A OE1   1 
ATOM 954  N NE2   . GLN A 1 157 ? 143.551 100.611 137.433 1.00 79.01  ? 157 GLN A NE2   1 
ATOM 955  N N     . ILE A 1 158 ? 137.346 102.762 139.185 1.00 75.67  ? 158 ILE A N     1 
ATOM 956  C CA    . ILE A 1 158 ? 136.056 103.339 138.819 1.00 74.03  ? 158 ILE A CA    1 
ATOM 957  C C     . ILE A 1 158 ? 135.620 104.378 139.845 1.00 71.63  ? 158 ILE A C     1 
ATOM 958  O O     . ILE A 1 158 ? 135.170 105.473 139.486 1.00 70.03  ? 158 ILE A O     1 
ATOM 959  C CB    . ILE A 1 158 ? 135.010 102.221 138.658 1.00 76.07  ? 158 ILE A CB    1 
ATOM 960  C CG1   . ILE A 1 158 ? 135.340 101.351 137.445 1.00 75.32  ? 158 ILE A CG1   1 
ATOM 961  C CG2   . ILE A 1 158 ? 133.616 102.796 138.529 1.00 73.22  ? 158 ILE A CG2   1 
ATOM 962  C CD1   . ILE A 1 158 ? 134.583 100.048 137.406 1.00 84.56  ? 158 ILE A CD1   1 
ATOM 963  N N     . LYS A 1 159 ? 135.774 104.066 141.134 1.00 73.34  ? 159 LYS A N     1 
ATOM 964  C CA    . LYS A 1 159 ? 135.438 105.026 142.182 1.00 70.87  ? 159 LYS A CA    1 
ATOM 965  C C     . LYS A 1 159 ? 136.362 106.237 142.158 1.00 68.29  ? 159 LYS A C     1 
ATOM 966  O O     . LYS A 1 159 ? 135.928 107.353 142.464 1.00 67.40  ? 159 LYS A O     1 
ATOM 967  C CB    . LYS A 1 159 ? 135.487 104.347 143.550 1.00 70.78  ? 159 LYS A CB    1 
ATOM 968  N N     . ARG A 1 160 ? 137.627 106.046 141.781 1.00 68.47  ? 160 ARG A N     1 
ATOM 969  C CA    . ARG A 1 160 ? 138.549 107.175 141.703 1.00 67.21  ? 160 ARG A CA    1 
ATOM 970  C C     . ARG A 1 160 ? 138.191 108.102 140.545 1.00 62.13  ? 160 ARG A C     1 
ATOM 971  O O     . ARG A 1 160 ? 138.227 109.331 140.691 1.00 61.53  ? 160 ARG A O     1 
ATOM 972  C CB    . ARG A 1 160 ? 139.978 106.656 141.567 1.00 71.46  ? 160 ARG A CB    1 
ATOM 973  C CG    . ARG A 1 160 ? 141.040 107.726 141.479 1.00 70.85  ? 160 ARG A CG    1 
ATOM 974  C CD    . ARG A 1 160 ? 141.217 108.456 142.801 1.00 71.39  ? 160 ARG A CD    1 
ATOM 975  N NE    . ARG A 1 160 ? 142.328 109.401 142.758 1.00 76.09  ? 160 ARG A NE    1 
ATOM 976  C CZ    . ARG A 1 160 ? 143.612 109.065 142.744 1.00 75.37  ? 160 ARG A CZ    1 
ATOM 977  N NH1   . ARG A 1 160 ? 144.002 107.804 142.843 1.00 74.32  ? 160 ARG A NH1   1 
ATOM 978  N NH2   . ARG A 1 160 ? 144.530 110.021 142.645 1.00 79.94  ? 160 ARG A NH2   1 
ATOM 979  N N     . VAL A 1 161 ? 137.828 107.530 139.391 1.00 62.43  ? 161 VAL A N     1 
ATOM 980  C CA    . VAL A 1 161 ? 137.354 108.337 138.266 1.00 59.48  ? 161 VAL A CA    1 
ATOM 981  C C     . VAL A 1 161 ? 136.048 109.035 138.628 1.00 56.97  ? 161 VAL A C     1 
ATOM 982  O O     . VAL A 1 161 ? 135.803 110.178 138.225 1.00 53.16  ? 161 VAL A O     1 
ATOM 983  C CB    . VAL A 1 161 ? 137.211 107.464 137.004 1.00 56.54  ? 161 VAL A CB    1 
ATOM 984  C CG1   . VAL A 1 161 ? 136.628 108.252 135.849 1.00 49.73  ? 161 VAL A CG1   1 
ATOM 985  C CG2   . VAL A 1 161 ? 138.558 106.924 136.594 1.00 58.22  ? 161 VAL A CG2   1 
ATOM 986  N N     . GLU A 1 162 ? 135.204 108.367 139.417 1.00 58.51  ? 162 GLU A N     1 
ATOM 987  C CA    . GLU A 1 162 ? 133.990 108.997 139.925 1.00 55.62  ? 162 GLU A CA    1 
ATOM 988  C C     . GLU A 1 162 ? 134.314 110.194 140.808 1.00 52.16  ? 162 GLU A C     1 
ATOM 989  O O     . GLU A 1 162 ? 133.639 111.230 140.738 1.00 49.16  ? 162 GLU A O     1 
ATOM 990  C CB    . GLU A 1 162 ? 133.162 107.970 140.699 1.00 60.69  ? 162 GLU A CB    1 
ATOM 991  C CG    . GLU A 1 162 ? 131.860 108.497 141.279 1.00 63.74  ? 162 GLU A CG    1 
ATOM 992  C CD    . GLU A 1 162 ? 130.717 108.432 140.289 1.00 65.27  ? 162 GLU A CD    1 
ATOM 993  O OE1   . GLU A 1 162 ? 130.975 108.544 139.074 1.00 61.37  ? 162 GLU A OE1   1 
ATOM 994  O OE2   . GLU A 1 162 ? 129.557 108.275 140.725 1.00 64.71  ? 162 GLU A OE2   1 
ATOM 995  N N     . ARG A 1 163 ? 135.344 110.064 141.650 1.00 53.29  ? 163 ARG A N     1 
ATOM 996  C CA    . ARG A 1 163 ? 135.787 111.186 142.471 1.00 54.69  ? 163 ARG A CA    1 
ATOM 997  C C     . ARG A 1 163 ? 136.279 112.340 141.610 1.00 51.60  ? 163 ARG A C     1 
ATOM 998  O O     . ARG A 1 163 ? 135.949 113.500 141.878 1.00 50.61  ? 163 ARG A O     1 
ATOM 999  C CB    . ARG A 1 163 ? 136.886 110.742 143.438 1.00 63.01  ? 163 ARG A CB    1 
ATOM 1000 C CG    . ARG A 1 163 ? 137.508 111.894 144.225 1.00 66.98  ? 163 ARG A CG    1 
ATOM 1001 C CD    . ARG A 1 163 ? 138.249 111.428 145.470 1.00 72.89  ? 163 ARG A CD    1 
ATOM 1002 N NE    . ARG A 1 163 ? 137.693 110.202 146.027 1.00 79.49  ? 163 ARG A NE    1 
ATOM 1003 C CZ    . ARG A 1 163 ? 138.378 109.078 146.185 1.00 79.73  ? 163 ARG A CZ    1 
ATOM 1004 N NH1   . ARG A 1 163 ? 139.651 108.990 145.839 1.00 79.81  ? 163 ARG A NH1   1 
ATOM 1005 N NH2   . ARG A 1 163 ? 137.770 108.016 146.704 1.00 81.17  ? 163 ARG A NH2   1 
ATOM 1006 N N     . ILE A 1 164 ? 137.058 112.039 140.564 1.00 51.23  ? 164 ILE A N     1 
ATOM 1007 C CA    . ILE A 1 164 ? 137.558 113.088 139.671 1.00 43.98  ? 164 ILE A CA    1 
ATOM 1008 C C     . ILE A 1 164 ? 136.407 113.785 138.955 1.00 41.43  ? 164 ILE A C     1 
ATOM 1009 O O     . ILE A 1 164 ? 136.422 115.008 138.766 1.00 39.35  ? 164 ILE A O     1 
ATOM 1010 C CB    . ILE A 1 164 ? 138.579 112.511 138.672 1.00 41.84  ? 164 ILE A CB    1 
ATOM 1011 C CG1   . ILE A 1 164 ? 139.740 111.849 139.407 1.00 48.67  ? 164 ILE A CG1   1 
ATOM 1012 C CG2   . ILE A 1 164 ? 139.118 113.593 137.760 1.00 37.83  ? 164 ILE A CG2   1 
ATOM 1013 C CD1   . ILE A 1 164 ? 140.667 111.085 138.498 1.00 53.27  ? 164 ILE A CD1   1 
ATOM 1014 N N     . PHE A 1 165 ? 135.388 113.022 138.556 1.00 43.91  ? 165 PHE A N     1 
ATOM 1015 C CA    . PHE A 1 165 ? 134.218 113.613 137.913 1.00 40.40  ? 165 PHE A CA    1 
ATOM 1016 C C     . PHE A 1 165 ? 133.437 114.500 138.873 1.00 39.63  ? 165 PHE A C     1 
ATOM 1017 O O     . PHE A 1 165 ? 132.946 115.564 138.482 1.00 40.33  ? 165 PHE A O     1 
ATOM 1018 C CB    . PHE A 1 165 ? 133.308 112.520 137.361 1.00 40.13  ? 165 PHE A CB    1 
ATOM 1019 C CG    . PHE A 1 165 ? 133.552 112.197 135.921 1.00 34.78  ? 165 PHE A CG    1 
ATOM 1020 C CD1   . PHE A 1 165 ? 134.638 111.432 135.545 1.00 35.48  ? 165 PHE A CD1   1 
ATOM 1021 C CD2   . PHE A 1 165 ? 132.695 112.664 134.943 1.00 34.53  ? 165 PHE A CD2   1 
ATOM 1022 C CE1   . PHE A 1 165 ? 134.861 111.132 134.223 1.00 38.19  ? 165 PHE A CE1   1 
ATOM 1023 C CE2   . PHE A 1 165 ? 132.916 112.368 133.619 1.00 34.56  ? 165 PHE A CE2   1 
ATOM 1024 C CZ    . PHE A 1 165 ? 134.001 111.600 133.260 1.00 37.52  ? 165 PHE A CZ    1 
ATOM 1025 N N     . ASN A 1 166 ? 133.300 114.077 140.128 1.00 39.65  ? 166 ASN A N     1 
ATOM 1026 C CA    . ASN A 1 166 ? 132.480 114.803 141.087 1.00 39.25  ? 166 ASN A CA    1 
ATOM 1027 C C     . ASN A 1 166 ? 133.249 115.829 141.909 1.00 39.51  ? 166 ASN A C     1 
ATOM 1028 O O     . ASN A 1 166 ? 132.628 116.538 142.706 1.00 39.00  ? 166 ASN A O     1 
ATOM 1029 C CB    . ASN A 1 166 ? 131.789 113.820 142.035 1.00 40.98  ? 166 ASN A CB    1 
ATOM 1030 C CG    . ASN A 1 166 ? 130.699 113.029 141.354 1.00 42.89  ? 166 ASN A CG    1 
ATOM 1031 O OD1   . ASN A 1 166 ? 130.128 113.470 140.359 1.00 44.73  ? 166 ASN A OD1   1 
ATOM 1032 N ND2   . ASN A 1 166 ? 130.401 111.851 141.887 1.00 45.16  ? 166 ASN A ND2   1 
ATOM 1033 N N     . LYS A 1 167 ? 134.568 115.926 141.744 1.00 40.47  ? 167 LYS A N     1 
ATOM 1034 C CA    . LYS A 1 167 ? 135.370 116.787 142.607 1.00 37.62  ? 167 LYS A CA    1 
ATOM 1035 C C     . LYS A 1 167 ? 135.083 118.258 142.332 1.00 32.27  ? 167 LYS A C     1 
ATOM 1036 O O     . LYS A 1 167 ? 135.048 118.691 141.178 1.00 37.67  ? 167 LYS A O     1 
ATOM 1037 C CB    . LYS A 1 167 ? 136.857 116.487 142.413 1.00 41.47  ? 167 LYS A CB    1 
ATOM 1038 C CG    . LYS A 1 167 ? 137.802 117.625 142.730 1.00 39.78  ? 167 LYS A CG    1 
ATOM 1039 C CD    . LYS A 1 167 ? 139.238 117.223 142.456 1.00 43.36  ? 167 LYS A CD    1 
ATOM 1040 C CE    . LYS A 1 167 ? 139.867 116.592 143.677 1.00 52.20  ? 167 LYS A CE    1 
ATOM 1041 N NZ    . LYS A 1 167 ? 140.022 117.586 144.772 1.00 58.20  ? 167 LYS A NZ    1 
ATOM 1042 N N     . GLN A 1 168 ? 134.869 119.021 143.399 1.00 26.23  ? 168 GLN A N     1 
ATOM 1043 C CA    . GLN A 1 168 ? 134.692 120.461 143.302 1.00 28.92  ? 168 GLN A CA    1 
ATOM 1044 C C     . GLN A 1 168 ? 136.040 121.137 143.504 1.00 32.51  ? 168 GLN A C     1 
ATOM 1045 O O     . GLN A 1 168 ? 136.715 120.897 144.509 1.00 35.34  ? 168 GLN A O     1 
ATOM 1046 C CB    . GLN A 1 168 ? 133.689 120.954 144.343 1.00 29.64  ? 168 GLN A CB    1 
ATOM 1047 C CG    . GLN A 1 168 ? 133.571 122.458 144.420 1.00 30.54  ? 168 GLN A CG    1 
ATOM 1048 C CD    . GLN A 1 168 ? 132.452 122.987 143.558 1.00 35.86  ? 168 GLN A CD    1 
ATOM 1049 O OE1   . GLN A 1 168 ? 131.540 122.251 143.187 1.00 42.47  ? 168 GLN A OE1   1 
ATOM 1050 N NE2   . GLN A 1 168 ? 132.514 124.271 143.230 1.00 34.30  ? 168 GLN A NE2   1 
ATOM 1051 N N     . TYR A 1 169 ? 136.429 121.982 142.551 1.00 30.95  ? 169 TYR A N     1 
ATOM 1052 C CA    . TYR A 1 169 ? 137.768 122.560 142.555 1.00 28.21  ? 169 TYR A CA    1 
ATOM 1053 C C     . TYR A 1 169 ? 137.796 123.904 143.272 1.00 31.36  ? 169 TYR A C     1 
ATOM 1054 O O     . TYR A 1 169 ? 138.507 124.071 144.266 1.00 36.19  ? 169 TYR A O     1 
ATOM 1055 C CB    . TYR A 1 169 ? 138.275 122.703 141.119 1.00 27.51  ? 169 TYR A CB    1 
ATOM 1056 C CG    . TYR A 1 169 ? 138.740 121.398 140.543 1.00 29.82  ? 169 TYR A CG    1 
ATOM 1057 C CD1   . TYR A 1 169 ? 137.837 120.498 140.009 1.00 32.90  ? 169 TYR A CD1   1 
ATOM 1058 C CD2   . TYR A 1 169 ? 140.078 121.053 140.558 1.00 31.71  ? 169 TYR A CD2   1 
ATOM 1059 C CE1   . TYR A 1 169 ? 138.254 119.298 139.495 1.00 35.85  ? 169 TYR A CE1   1 
ATOM 1060 C CE2   . TYR A 1 169 ? 140.505 119.855 140.044 1.00 35.02  ? 169 TYR A CE2   1 
ATOM 1061 C CZ    . TYR A 1 169 ? 139.589 118.982 139.511 1.00 37.73  ? 169 TYR A CZ    1 
ATOM 1062 O OH    . TYR A 1 169 ? 140.006 117.779 138.999 1.00 43.13  ? 169 TYR A OH    1 
ATOM 1063 N N     . ARG A 1 170 ? 137.028 124.864 142.782 1.00 30.49  ? 170 ARG A N     1 
ATOM 1064 C CA    . ARG A 1 170 ? 136.874 126.128 143.477 1.00 31.27  ? 170 ARG A CA    1 
ATOM 1065 C C     . ARG A 1 170 ? 135.689 126.012 144.424 1.00 31.90  ? 170 ARG A C     1 
ATOM 1066 O O     . ARG A 1 170 ? 134.561 125.812 143.957 1.00 39.34  ? 170 ARG A O     1 
ATOM 1067 C CB    . ARG A 1 170 ? 136.662 127.255 142.486 1.00 30.92  ? 170 ARG A CB    1 
ATOM 1068 C CG    . ARG A 1 170 ? 137.826 127.434 141.528 1.00 31.10  ? 170 ARG A CG    1 
ATOM 1069 C CD    . ARG A 1 170 ? 137.594 128.572 140.559 1.00 28.59  ? 170 ARG A CD    1 
ATOM 1070 N NE    . ARG A 1 170 ? 137.468 129.853 141.238 1.00 26.46  ? 170 ARG A NE    1 
ATOM 1071 C CZ    . ARG A 1 170 ? 138.416 130.777 141.262 1.00 26.77  ? 170 ARG A CZ    1 
ATOM 1072 N NH1   . ARG A 1 170 ? 139.575 130.592 140.655 1.00 31.20  ? 170 ARG A NH1   1 
ATOM 1073 N NH2   . ARG A 1 170 ? 138.194 131.918 141.905 1.00 28.75  ? 170 ARG A NH2   1 
ATOM 1074 N N     . PRO A 1 171 ? 135.892 126.096 145.737 1.00 26.66  ? 171 PRO A N     1 
ATOM 1075 C CA    . PRO A 1 171 ? 134.817 125.753 146.677 1.00 30.20  ? 171 PRO A CA    1 
ATOM 1076 C C     . PRO A 1 171 ? 133.687 126.770 146.671 1.00 31.98  ? 171 PRO A C     1 
ATOM 1077 O O     . PRO A 1 171 ? 133.904 127.970 146.492 1.00 33.62  ? 171 PRO A O     1 
ATOM 1078 C CB    . PRO A 1 171 ? 135.531 125.720 148.031 1.00 33.04  ? 171 PRO A CB    1 
ATOM 1079 C CG    . PRO A 1 171 ? 136.728 126.569 147.838 1.00 33.34  ? 171 PRO A CG    1 
ATOM 1080 C CD    . PRO A 1 171 ? 137.157 126.384 146.426 1.00 29.19  ? 171 PRO A CD    1 
ATOM 1081 N N     . LYS A 1 172 ? 132.468 126.271 146.882 1.00 31.99  ? 172 LYS A N     1 
ATOM 1082 C CA    . LYS A 1 172 ? 131.253 127.082 146.801 1.00 29.67  ? 172 LYS A CA    1 
ATOM 1083 C C     . LYS A 1 172 ? 131.446 127.768 148.152 1.00 30.28  ? 172 LYS A C     1 
ATOM 1084 O O     . LYS A 1 172 ? 131.331 127.169 149.222 1.00 40.05  ? 172 LYS A O     1 
ATOM 1085 C CB    . LYS A 1 172 ? 130.033 126.199 146.581 1.00 30.30  ? 172 LYS A CB    1 
ATOM 1086 C CG    . LYS A 1 172 ? 130.056 125.411 145.289 1.00 34.59  ? 172 LYS A CG    1 
ATOM 1087 C CD    . LYS A 1 172 ? 128.685 124.840 144.967 1.00 33.91  ? 172 LYS A CD    1 
ATOM 1088 C CE    . LYS A 1 172 ? 128.220 123.874 146.042 1.00 31.24  ? 172 LYS A CE    1 
ATOM 1089 N NZ    . LYS A 1 172 ? 126.841 123.386 145.780 1.00 33.90  ? 172 LYS A NZ    1 
ATOM 1090 N N     . ARG A 1 173 ? 131.748 129.058 148.085 1.00 27.74  ? 173 ARG A N     1 
ATOM 1091 C CA    . ARG A 1 173 ? 131.895 129.883 149.276 1.00 32.49  ? 173 ARG A CA    1 
ATOM 1092 C C     . ARG A 1 173 ? 130.938 131.022 148.894 1.00 32.38  ? 173 ARG A C     1 
ATOM 1093 O O     . ARG A 1 173 ? 131.233 131.858 148.035 1.00 33.31  ? 173 ARG A O     1 
ATOM 1094 C CB    . ARG A 1 173 ? 133.333 130.276 149.657 1.00 32.91  ? 173 ARG A CB    1 
ATOM 1095 C CG    . ARG A 1 173 ? 134.075 131.330 148.849 1.00 33.07  ? 173 ARG A CG    1 
ATOM 1096 C CD    . ARG A 1 173 ? 135.568 131.385 149.122 1.00 34.25  ? 173 ARG A CD    1 
ATOM 1097 N NE    . ARG A 1 173 ? 136.207 130.086 149.264 1.00 37.08  ? 173 ARG A NE    1 
ATOM 1098 C CZ    . ARG A 1 173 ? 137.175 129.839 150.133 1.00 40.83  ? 173 ARG A CZ    1 
ATOM 1099 N NH1   . ARG A 1 173 ? 137.681 130.796 150.889 1.00 40.76  ? 173 ARG A NH1   1 
ATOM 1100 N NH2   . ARG A 1 173 ? 137.665 128.607 150.230 1.00 45.24  ? 173 ARG A NH2   1 
ATOM 1101 N N     . PHE A 1 174 ? 129.727 130.973 149.443 1.00 32.14  ? 174 PHE A N     1 
ATOM 1102 C CA    . PHE A 1 174 ? 128.664 131.874 149.005 1.00 31.41  ? 174 PHE A CA    1 
ATOM 1103 C C     . PHE A 1 174 ? 127.833 132.483 150.127 1.00 39.29  ? 174 PHE A C     1 
ATOM 1104 O O     . PHE A 1 174 ? 127.201 133.518 149.895 1.00 42.33  ? 174 PHE A O     1 
ATOM 1105 C CB    . PHE A 1 174 ? 127.732 131.138 148.036 1.00 36.35  ? 174 PHE A CB    1 
ATOM 1106 C CG    . PHE A 1 174 ? 126.828 132.043 147.253 1.00 43.01  ? 174 PHE A CG    1 
ATOM 1107 C CD1   . PHE A 1 174 ? 127.321 133.183 146.647 1.00 39.96  ? 174 PHE A CD1   1 
ATOM 1108 C CD2   . PHE A 1 174 ? 125.486 131.738 147.103 1.00 49.99  ? 174 PHE A CD2   1 
ATOM 1109 C CE1   . PHE A 1 174 ? 126.495 134.007 145.913 1.00 40.72  ? 174 PHE A CE1   1 
ATOM 1110 C CE2   . PHE A 1 174 ? 124.652 132.562 146.373 1.00 50.92  ? 174 PHE A CE2   1 
ATOM 1111 C CZ    . PHE A 1 174 ? 125.159 133.701 145.778 1.00 45.22  ? 174 PHE A CZ    1 
ATOM 1112 N N     . ASN A 1 175 ? 127.801 131.887 151.323 1.00 39.55  ? 175 ASN A N     1 
ATOM 1113 C CA    . ASN A 1 175 ? 126.791 132.240 152.317 1.00 33.95  ? 175 ASN A CA    1 
ATOM 1114 C C     . ASN A 1 175 ? 127.004 133.634 152.895 1.00 37.73  ? 175 ASN A C     1 
ATOM 1115 O O     . ASN A 1 175 ? 126.041 134.382 153.092 1.00 44.74  ? 175 ASN A O     1 
ATOM 1116 C CB    . ASN A 1 175 ? 126.780 131.194 153.426 1.00 37.19  ? 175 ASN A CB    1 
ATOM 1117 C CG    . ASN A 1 175 ? 126.784 129.780 152.887 1.00 42.59  ? 175 ASN A CG    1 
ATOM 1118 O OD1   . ASN A 1 175 ? 127.791 129.076 152.959 1.00 42.84  ? 175 ASN A OD1   1 
ATOM 1119 N ND2   . ASN A 1 175 ? 125.655 129.358 152.338 1.00 41.73  ? 175 ASN A ND2   1 
ATOM 1120 N N     . ASN A 1 176 ? 128.251 134.006 153.171 1.00 37.96  ? 176 ASN A N     1 
ATOM 1121 C CA    . ASN A 1 176 ? 128.525 135.256 153.871 1.00 40.61  ? 176 ASN A CA    1 
ATOM 1122 C C     . ASN A 1 176 ? 129.301 136.207 152.967 1.00 39.12  ? 176 ASN A C     1 
ATOM 1123 O O     . ASN A 1 176 ? 130.329 136.763 153.364 1.00 41.83  ? 176 ASN A O     1 
ATOM 1124 C CB    . ASN A 1 176 ? 129.290 134.978 155.169 1.00 46.32  ? 176 ASN A CB    1 
ATOM 1125 C CG    . ASN A 1 176 ? 129.314 136.172 156.104 1.00 49.14  ? 176 ASN A CG    1 
ATOM 1126 O OD1   . ASN A 1 176 ? 128.476 137.065 156.009 1.00 52.41  ? 176 ASN A OD1   1 
ATOM 1127 N ND2   . ASN A 1 176 ? 130.282 136.193 157.009 1.00 52.41  ? 176 ASN A ND2   1 
ATOM 1128 N N     . ARG A 1 177 ? 128.835 136.382 151.732 1.00 36.64  ? 177 ARG A N     1 
ATOM 1129 C CA    . ARG A 1 177 ? 129.651 137.079 150.747 1.00 34.82  ? 177 ARG A CA    1 
ATOM 1130 C C     . ARG A 1 177 ? 129.463 138.590 150.797 1.00 39.79  ? 177 ARG A C     1 
ATOM 1131 O O     . ARG A 1 177 ? 130.444 139.338 150.840 1.00 42.28  ? 177 ARG A O     1 
ATOM 1132 C CB    . ARG A 1 177 ? 129.357 136.539 149.350 1.00 37.43  ? 177 ARG A CB    1 
ATOM 1133 C CG    . ARG A 1 177 ? 130.362 135.489 148.956 1.00 36.86  ? 177 ARG A CG    1 
ATOM 1134 C CD    . ARG A 1 177 ? 131.724 136.123 149.003 1.00 28.63  ? 177 ARG A CD    1 
ATOM 1135 N NE    . ARG A 1 177 ? 132.809 135.165 149.103 1.00 24.55  ? 177 ARG A NE    1 
ATOM 1136 C CZ    . ARG A 1 177 ? 134.081 135.520 149.171 1.00 32.49  ? 177 ARG A CZ    1 
ATOM 1137 N NH1   . ARG A 1 177 ? 134.447 136.788 149.107 1.00 38.39  ? 177 ARG A NH1   1 
ATOM 1138 N NH2   . ARG A 1 177 ? 135.009 134.585 149.316 1.00 36.76  ? 177 ARG A NH2   1 
ATOM 1139 N N     . ILE A 1 178 ? 128.225 139.061 150.785 1.00 43.79  ? 178 ILE A N     1 
ATOM 1140 C CA    . ILE A 1 178 ? 127.971 140.496 150.831 1.00 48.26  ? 178 ILE A CA    1 
ATOM 1141 C C     . ILE A 1 178 ? 128.163 140.974 152.262 1.00 57.74  ? 178 ILE A C     1 
ATOM 1142 O O     . ILE A 1 178 ? 127.583 140.413 153.197 1.00 61.84  ? 178 ILE A O     1 
ATOM 1143 C CB    . ILE A 1 178 ? 126.558 140.818 150.320 1.00 50.72  ? 178 ILE A CB    1 
ATOM 1144 C CG1   . ILE A 1 178 ? 126.461 140.545 148.823 1.00 56.17  ? 178 ILE A CG1   1 
ATOM 1145 C CG2   . ILE A 1 178 ? 126.209 142.269 150.598 1.00 57.69  ? 178 ILE A CG2   1 
ATOM 1146 C CD1   . ILE A 1 178 ? 125.057 140.256 148.361 1.00 59.44  ? 178 ILE A CD1   1 
ATOM 1147 N N     . LEU A 1 179 ? 128.981 142.007 152.440 1.00 58.19  ? 179 LEU A N     1 
ATOM 1148 C CA    . LEU A 1 179 ? 129.280 142.491 153.781 1.00 56.89  ? 179 LEU A CA    1 
ATOM 1149 C C     . LEU A 1 179 ? 128.838 143.934 153.965 1.00 66.16  ? 179 LEU A C     1 
ATOM 1150 O O     . LEU A 1 179 ? 129.613 144.762 154.453 1.00 71.84  ? 179 LEU A O     1 
ATOM 1151 C CB    . LEU A 1 179 ? 130.771 142.360 154.081 1.00 57.02  ? 179 LEU A CB    1 
ATOM 1152 C CG    . LEU A 1 179 ? 131.354 140.953 154.005 1.00 49.47  ? 179 LEU A CG    1 
ATOM 1153 C CD1   . LEU A 1 179 ? 132.864 141.024 154.002 1.00 53.37  ? 179 LEU A CD1   1 
ATOM 1154 C CD2   . LEU A 1 179 ? 130.861 140.119 155.170 1.00 45.55  ? 179 LEU A CD2   1 
ATOM 1155 N N     . THR A 1 180 ? 127.611 144.249 153.545 1.00 69.81  ? 180 THR A N     1 
ATOM 1156 C CA    . THR A 1 180 ? 127.007 145.541 153.846 1.00 74.94  ? 180 THR A CA    1 
ATOM 1157 C C     . THR A 1 180 ? 126.912 145.695 155.356 1.00 76.74  ? 180 THR A C     1 
ATOM 1158 O O     . THR A 1 180 ? 126.121 145.006 156.005 1.00 77.06  ? 180 THR A O     1 
ATOM 1159 C CB    . THR A 1 180 ? 125.621 145.664 153.210 1.00 76.85  ? 180 THR A CB    1 
ATOM 1160 O OG1   . THR A 1 180 ? 124.946 144.402 153.284 1.00 77.07  ? 180 THR A OG1   1 
ATOM 1161 C CG2   . THR A 1 180 ? 125.736 146.086 151.752 1.00 74.75  ? 180 THR A CG2   1 
ATOM 1162 N N     . LYS A 1 181 ? 127.718 146.585 155.924 1.00 77.46  ? 181 LYS A N     1 
ATOM 1163 C CA    . LYS A 1 181 ? 127.925 146.599 157.361 1.00 83.48  ? 181 LYS A CA    1 
ATOM 1164 C C     . LYS A 1 181 ? 127.599 147.955 157.962 1.00 91.09  ? 181 LYS A C     1 
ATOM 1165 O O     . LYS A 1 181 ? 127.918 149.004 157.393 1.00 87.51  ? 181 LYS A O     1 
ATOM 1166 C CB    . LYS A 1 181 ? 129.373 146.213 157.720 1.00 81.68  ? 181 LYS A CB    1 
ATOM 1167 C CG    . LYS A 1 181 ? 130.448 147.061 157.056 1.00 77.82  ? 181 LYS A CG    1 
ATOM 1168 C CD    . LYS A 1 181 ? 131.839 146.665 157.525 1.00 74.32  ? 181 LYS A CD    1 
ATOM 1169 C CE    . LYS A 1 181 ? 132.161 145.225 157.173 1.00 67.72  ? 181 LYS A CE    1 
ATOM 1170 N NZ    . LYS A 1 181 ? 133.578 144.889 157.473 1.00 62.44  ? 181 LYS A NZ    1 
ATOM 1171 N N     . CYS A 1 182 ? 126.923 147.911 159.101 1.00 97.52  ? 182 CYS A N     1 
ATOM 1172 C CA    . CYS A 1 182 ? 126.968 148.949 160.117 1.00 99.87  ? 182 CYS A CA    1 
ATOM 1173 C C     . CYS A 1 182 ? 127.515 148.348 161.402 1.00 104.77 ? 182 CYS A C     1 
ATOM 1174 O O     . CYS A 1 182 ? 127.047 148.645 162.503 1.00 111.75 ? 182 CYS A O     1 
ATOM 1175 C CB    . CYS A 1 182 ? 125.595 149.576 160.340 1.00 101.19 ? 182 CYS A CB    1 
ATOM 1176 S SG    . CYS A 1 182 ? 124.951 150.479 158.917 1.00 101.48 ? 182 CYS A SG    1 
ATOM 1177 N N     . LYS A 1 183 ? 128.504 147.458 161.249 1.00 99.77  ? 183 LYS A N     1 
ATOM 1178 C CA    . LYS A 1 183 ? 129.096 146.771 162.394 1.00 99.96  ? 183 LYS A CA    1 
ATOM 1179 C C     . LYS A 1 183 ? 129.792 147.757 163.321 1.00 106.74 ? 183 LYS A C     1 
ATOM 1180 O O     . LYS A 1 183 ? 129.734 147.614 164.548 1.00 109.37 ? 183 LYS A O     1 
ATOM 1181 C CB    . LYS A 1 183 ? 130.069 145.698 161.910 1.00 89.83  ? 183 LYS A CB    1 
ATOM 1182 C CG    . LYS A 1 183 ? 129.403 144.542 161.181 1.00 84.21  ? 183 LYS A CG    1 
ATOM 1183 C CD    . LYS A 1 183 ? 130.390 143.426 160.901 1.00 75.01  ? 183 LYS A CD    1 
ATOM 1184 C CE    . LYS A 1 183 ? 129.720 142.272 160.183 1.00 65.43  ? 183 LYS A CE    1 
ATOM 1185 N NZ    . LYS A 1 183 ? 130.695 141.197 159.878 1.00 62.60  ? 183 LYS A NZ    1 
ATOM 1186 N N     . VAL A 1 184 ? 130.458 148.761 162.755 1.00 108.89 ? 184 VAL A N     1 
ATOM 1187 C CA    . VAL A 1 184 ? 130.759 149.960 163.524 1.00 114.68 ? 184 VAL A CA    1 
ATOM 1188 C C     . VAL A 1 184 ? 129.445 150.694 163.760 1.00 117.37 ? 184 VAL A C     1 
ATOM 1189 O O     . VAL A 1 184 ? 128.702 150.999 162.819 1.00 117.37 ? 184 VAL A O     1 
ATOM 1190 C CB    . VAL A 1 184 ? 131.812 150.827 162.815 1.00 119.46 ? 184 VAL A CB    1 
ATOM 1191 C CG1   . VAL A 1 184 ? 131.490 151.002 161.327 1.00 117.08 ? 184 VAL A CG1   1 
ATOM 1192 C CG2   . VAL A 1 184 ? 131.943 152.178 163.499 1.00 122.72 ? 184 VAL A CG2   1 
ATOM 1193 N N     . GLU A 1 185 ? 129.128 150.938 165.030 1.00 118.94 ? 185 GLU A N     1 
ATOM 1194 C CA    . GLU A 1 185 ? 127.762 151.266 165.422 1.00 120.44 ? 185 GLU A CA    1 
ATOM 1195 C C     . GLU A 1 185 ? 127.313 152.663 165.009 1.00 123.27 ? 185 GLU A C     1 
ATOM 1196 O O     . GLU A 1 185 ? 126.108 152.939 165.049 1.00 122.53 ? 185 GLU A O     1 
ATOM 1197 C CB    . GLU A 1 185 ? 127.614 151.101 166.933 1.00 120.37 ? 185 GLU A CB    1 
ATOM 1198 C CG    . GLU A 1 185 ? 127.966 149.705 167.426 1.00 117.55 ? 185 GLU A CG    1 
ATOM 1199 C CD    . GLU A 1 185 ? 127.971 149.599 168.936 1.00 117.27 ? 185 GLU A CD    1 
ATOM 1200 O OE1   . GLU A 1 185 ? 127.393 150.485 169.601 1.00 119.77 ? 185 GLU A OE1   1 
ATOM 1201 O OE2   . GLU A 1 185 ? 128.547 148.623 169.459 1.00 112.76 ? 185 GLU A OE2   1 
ATOM 1202 N N     . ASP A 1 186 ? 128.230 153.539 164.617 1.00 123.23 ? 186 ASP A N     1 
ATOM 1203 C CA    . ASP A 1 186 ? 127.862 154.892 164.226 1.00 122.08 ? 186 ASP A CA    1 
ATOM 1204 C C     . ASP A 1 186 ? 127.213 154.920 162.846 1.00 117.53 ? 186 ASP A C     1 
ATOM 1205 O O     . ASP A 1 186 ? 126.461 155.839 162.523 1.00 114.77 ? 186 ASP A O     1 
ATOM 1206 C CB    . ASP A 1 186 ? 129.087 155.806 164.253 1.00 122.33 ? 186 ASP A CB    1 
ATOM 1207 C CG    . ASP A 1 186 ? 129.891 155.660 165.524 1.00 121.36 ? 186 ASP A CG    1 
ATOM 1208 O OD1   . ASP A 1 186 ? 130.713 154.725 165.598 1.00 119.73 ? 186 ASP A OD1   1 
ATOM 1209 O OD2   . ASP A 1 186 ? 129.697 156.474 166.451 1.00 121.49 ? 186 ASP A OD2   1 
ATOM 1210 N N     . LYS A 1 195 ? 117.915 136.116 157.169 1.00 87.95  ? 195 LYS A N     1 
ATOM 1211 C CA    . LYS A 1 195 ? 117.141 134.913 157.447 1.00 94.62  ? 195 LYS A CA    1 
ATOM 1212 C C     . LYS A 1 195 ? 117.387 134.423 158.870 1.00 96.44  ? 195 LYS A C     1 
ATOM 1213 O O     . LYS A 1 195 ? 116.649 133.584 159.385 1.00 102.88 ? 195 LYS A O     1 
ATOM 1214 C CB    . LYS A 1 195 ? 117.485 133.810 156.446 1.00 92.08  ? 195 LYS A CB    1 
ATOM 1215 C CG    . LYS A 1 195 ? 118.943 133.392 156.470 1.00 90.36  ? 195 LYS A CG    1 
ATOM 1216 C CD    . LYS A 1 195 ? 119.161 132.098 155.709 1.00 89.53  ? 195 LYS A CD    1 
ATOM 1217 C CE    . LYS A 1 195 ? 120.599 131.628 155.837 1.00 92.08  ? 195 LYS A CE    1 
ATOM 1218 N NZ    . LYS A 1 195 ? 120.834 130.351 155.111 1.00 94.65  ? 195 LYS A NZ    1 
ATOM 1219 N N     . ASN A 1 196 ? 118.433 134.955 159.501 1.00 90.73  ? 196 ASN A N     1 
ATOM 1220 C CA    . ASN A 1 196 ? 118.787 134.607 160.869 1.00 89.62  ? 196 ASN A CA    1 
ATOM 1221 C C     . ASN A 1 196 ? 118.346 135.672 161.864 1.00 93.98  ? 196 ASN A C     1 
ATOM 1222 O O     . ASN A 1 196 ? 118.822 135.687 163.003 1.00 93.29  ? 196 ASN A O     1 
ATOM 1223 C CB    . ASN A 1 196 ? 120.293 134.371 160.974 1.00 90.68  ? 196 ASN A CB    1 
ATOM 1224 C CG    . ASN A 1 196 ? 120.747 133.164 160.180 1.00 93.02  ? 196 ASN A CG    1 
ATOM 1225 O OD1   . ASN A 1 196 ? 119.931 132.358 159.736 1.00 94.99  ? 196 ASN A OD1   1 
ATOM 1226 N ND2   . ASN A 1 196 ? 122.055 133.033 159.996 1.00 90.83  ? 196 ASN A ND2   1 
ATOM 1227 N N     . VAL A 1 197 ? 117.444 136.558 161.452 1.00 99.71  ? 197 VAL A N     1 
ATOM 1228 C CA    . VAL A 1 197 ? 117.009 137.693 162.258 1.00 104.74 ? 197 VAL A CA    1 
ATOM 1229 C C     . VAL A 1 197 ? 115.481 137.699 162.323 1.00 113.99 ? 197 VAL A C     1 
ATOM 1230 O O     . VAL A 1 197 ? 114.856 138.725 162.628 1.00 120.21 ? 197 VAL A O     1 
ATOM 1231 C CB    . VAL A 1 197 ? 117.633 138.995 161.698 1.00 105.33 ? 197 VAL A CB    1 
ATOM 1232 C CG1   . VAL A 1 197 ? 116.889 139.543 160.466 1.00 109.87 ? 197 VAL A CG1   1 
ATOM 1233 C CG2   . VAL A 1 197 ? 117.779 140.054 162.793 1.00 107.37 ? 197 VAL A CG2   1 
ATOM 1234 N N     . ARG A 1 198 ? 114.893 136.512 162.106 1.00 113.61 ? 198 ARG A N     1 
ATOM 1235 C CA    . ARG A 1 198 ? 113.444 136.303 162.048 1.00 119.37 ? 198 ARG A CA    1 
ATOM 1236 C C     . ARG A 1 198 ? 112.554 136.783 163.188 1.00 126.03 ? 198 ARG A C     1 
ATOM 1237 O O     . ARG A 1 198 ? 111.447 137.287 162.955 1.00 128.73 ? 198 ARG A O     1 
ATOM 1238 C CB    . ARG A 1 198 ? 113.147 134.801 162.029 1.00 118.78 ? 198 ARG A CB    1 
ATOM 1239 C CG    . ARG A 1 198 ? 113.605 134.038 160.804 1.00 117.91 ? 198 ARG A CG    1 
ATOM 1240 C CD    . ARG A 1 198 ? 113.158 132.590 160.936 1.00 122.97 ? 198 ARG A CD    1 
ATOM 1241 N NE    . ARG A 1 198 ? 113.579 131.774 159.805 1.00 130.32 ? 198 ARG A NE    1 
ATOM 1242 C CZ    . ARG A 1 198 ? 112.928 131.700 158.652 1.00 135.79 ? 198 ARG A CZ    1 
ATOM 1243 N NH1   . ARG A 1 198 ? 111.785 132.338 158.463 1.00 139.80 ? 198 ARG A NH1   1 
ATOM 1244 N NH2   . ARG A 1 198 ? 113.428 130.955 157.670 1.00 136.00 ? 198 ARG A NH2   1 
ATOM 1245 N N     . ASP A 1 199 ? 113.045 136.652 164.427 1.00 127.11 ? 199 ASP A N     1 
ATOM 1246 C CA    . ASP A 1 199 ? 112.229 136.935 165.606 1.00 129.36 ? 199 ASP A CA    1 
ATOM 1247 C C     . ASP A 1 199 ? 112.387 138.429 165.850 1.00 131.55 ? 199 ASP A C     1 
ATOM 1248 O O     . ASP A 1 199 ? 111.415 139.115 166.190 1.00 135.86 ? 199 ASP A O     1 
ATOM 1249 C CB    . ASP A 1 199 ? 112.658 136.136 166.837 1.00 129.04 ? 199 ASP A CB    1 
ATOM 1250 C CG    . ASP A 1 199 ? 114.147 136.225 167.104 1.00 126.88 ? 199 ASP A CG    1 
ATOM 1251 O OD1   . ASP A 1 199 ? 114.902 136.538 166.159 1.00 124.06 ? 199 ASP A OD1   1 
ATOM 1252 O OD2   . ASP A 1 199 ? 114.562 135.988 168.257 1.00 129.19 ? 199 ASP A OD2   1 
ATOM 1253 N N     . LEU A 1 200 ? 113.597 138.955 165.644 1.00 128.18 ? 200 LEU A N     1 
ATOM 1254 C CA    . LEU A 1 200 ? 113.817 140.390 165.771 1.00 129.12 ? 200 LEU A CA    1 
ATOM 1255 C C     . LEU A 1 200 ? 112.998 141.165 164.749 1.00 132.73 ? 200 LEU A C     1 
ATOM 1256 O O     . LEU A 1 200 ? 112.386 142.185 165.084 1.00 138.74 ? 200 LEU A O     1 
ATOM 1257 C CB    . LEU A 1 200 ? 115.304 140.706 165.617 1.00 125.40 ? 200 LEU A CB    1 
ATOM 1258 C CG    . LEU A 1 200 ? 115.997 141.373 166.806 1.00 126.30 ? 200 LEU A CG    1 
ATOM 1259 C CD1   . LEU A 1 200 ? 117.376 141.869 166.405 1.00 123.83 ? 200 LEU A CD1   1 
ATOM 1260 C CD2   . LEU A 1 200 ? 115.157 142.511 167.359 1.00 130.30 ? 200 LEU A CD2   1 
ATOM 1261 N N     . LEU A 1 201 ? 112.948 140.675 163.506 1.00 129.31 ? 201 LEU A N     1 
ATOM 1262 C CA    . LEU A 1 201 ? 112.231 141.381 162.446 1.00 131.25 ? 201 LEU A CA    1 
ATOM 1263 C C     . LEU A 1 201 ? 110.729 141.414 162.705 1.00 137.63 ? 201 LEU A C     1 
ATOM 1264 O O     . LEU A 1 201 ? 110.091 142.467 162.551 1.00 140.40 ? 201 LEU A O     1 
ATOM 1265 C CB    . LEU A 1 201 ? 112.531 140.736 161.093 1.00 127.66 ? 201 LEU A CB    1 
ATOM 1266 C CG    . LEU A 1 201 ? 113.492 141.481 160.162 1.00 126.28 ? 201 LEU A CG    1 
ATOM 1267 C CD1   . LEU A 1 201 ? 113.323 141.004 158.731 1.00 128.92 ? 201 LEU A CD1   1 
ATOM 1268 C CD2   . LEU A 1 201 ? 113.298 142.989 160.246 1.00 125.75 ? 201 LEU A CD2   1 
ATOM 1269 N N     . ILE A 1 202 ? 110.144 140.282 163.113 1.00 139.32 ? 202 ILE A N     1 
ATOM 1270 C CA    . ILE A 1 202 ? 108.713 140.313 163.409 1.00 143.85 ? 202 ILE A CA    1 
ATOM 1271 C C     . ILE A 1 202 ? 108.455 141.104 164.684 1.00 146.25 ? 202 ILE A C     1 
ATOM 1272 O O     . ILE A 1 202 ? 107.362 141.648 164.866 1.00 149.46 ? 202 ILE A O     1 
ATOM 1273 C CB    . ILE A 1 202 ? 108.106 138.901 163.503 1.00 142.72 ? 202 ILE A CB    1 
ATOM 1274 C CG1   . ILE A 1 202 ? 109.027 137.969 164.276 1.00 140.96 ? 202 ILE A CG1   1 
ATOM 1275 C CG2   . ILE A 1 202 ? 107.820 138.356 162.111 1.00 145.46 ? 202 ILE A CG2   1 
ATOM 1276 C CD1   . ILE A 1 202 ? 108.610 136.526 164.284 1.00 146.48 ? 202 ILE A CD1   1 
ATOM 1277 N N     . GLU A 1 203 ? 109.441 141.189 165.583 1.00 143.81 ? 203 GLU A N     1 
ATOM 1278 C CA    . GLU A 1 203 ? 109.292 142.059 166.744 1.00 145.75 ? 203 GLU A CA    1 
ATOM 1279 C C     . GLU A 1 203 ? 109.216 143.520 166.309 1.00 150.01 ? 203 GLU A C     1 
ATOM 1280 O O     . GLU A 1 203 ? 108.390 144.282 166.821 1.00 152.98 ? 203 GLU A O     1 
ATOM 1281 C CB    . GLU A 1 203 ? 110.455 141.823 167.713 1.00 144.71 ? 203 GLU A CB    1 
ATOM 1282 C CG    . GLU A 1 203 ? 110.546 142.727 168.950 1.00 148.41 ? 203 GLU A CG    1 
ATOM 1283 C CD    . GLU A 1 203 ? 109.197 143.061 169.571 1.00 152.32 ? 203 GLU A CD    1 
ATOM 1284 O OE1   . GLU A 1 203 ? 108.552 142.140 170.114 1.00 151.17 ? 203 GLU A OE1   1 
ATOM 1285 O OE2   . GLU A 1 203 ? 108.806 144.247 169.570 1.00 155.02 ? 203 GLU A OE2   1 
ATOM 1286 N N     . ASN A 1 204 ? 110.047 143.920 165.336 1.00 149.32 ? 204 ASN A N     1 
ATOM 1287 C CA    . ASN A 1 204 ? 109.951 145.291 164.828 1.00 151.37 ? 204 ASN A CA    1 
ATOM 1288 C C     . ASN A 1 204 ? 108.638 145.540 164.100 1.00 154.32 ? 204 ASN A C     1 
ATOM 1289 O O     . ASN A 1 204 ? 108.110 146.656 164.153 1.00 157.66 ? 204 ASN A O     1 
ATOM 1290 C CB    . ASN A 1 204 ? 111.096 145.656 163.878 1.00 149.18 ? 204 ASN A CB    1 
ATOM 1291 C CG    . ASN A 1 204 ? 112.429 145.117 164.311 1.00 145.41 ? 204 ASN A CG    1 
ATOM 1292 O OD1   . ASN A 1 204 ? 113.071 144.376 163.571 1.00 142.32 ? 204 ASN A OD1   1 
ATOM 1293 N ND2   . ASN A 1 204 ? 112.857 145.479 165.513 1.00 143.84 ? 204 ASN A ND2   1 
ATOM 1294 N N     . ILE A 1 205 ? 108.113 144.538 163.393 1.00 154.55 ? 205 ILE A N     1 
ATOM 1295 C CA    . ILE A 1 205 ? 106.868 144.746 162.657 1.00 158.96 ? 205 ILE A CA    1 
ATOM 1296 C C     . ILE A 1 205 ? 105.681 144.852 163.613 1.00 162.32 ? 205 ILE A C     1 
ATOM 1297 O O     . ILE A 1 205 ? 104.860 145.771 163.511 1.00 165.05 ? 205 ILE A O     1 
ATOM 1298 C CB    . ILE A 1 205 ? 106.663 143.628 161.620 1.00 156.98 ? 205 ILE A CB    1 
ATOM 1299 C CG1   . ILE A 1 205 ? 107.753 143.690 160.550 1.00 152.96 ? 205 ILE A CG1   1 
ATOM 1300 C CG2   . ILE A 1 205 ? 105.294 143.747 160.981 1.00 159.63 ? 205 ILE A CG2   1 
ATOM 1301 C CD1   . ILE A 1 205 ? 107.713 144.948 159.708 1.00 151.64 ? 205 ILE A CD1   1 
ATOM 1302 N N     . VAL A 1 206 ? 105.585 143.925 164.568 1.00 161.53 ? 206 VAL A N     1 
ATOM 1303 C CA    . VAL A 1 206 ? 104.386 143.809 165.397 1.00 165.78 ? 206 VAL A CA    1 
ATOM 1304 C C     . VAL A 1 206 ? 104.329 144.870 166.501 1.00 169.75 ? 206 VAL A C     1 
ATOM 1305 O O     . VAL A 1 206 ? 103.230 145.204 166.969 1.00 173.97 ? 206 VAL A O     1 
ATOM 1306 C CB    . VAL A 1 206 ? 104.322 142.356 165.915 1.00 165.71 ? 206 VAL A CB    1 
ATOM 1307 C CG1   . VAL A 1 206 ? 103.172 142.110 166.878 1.00 170.33 ? 206 VAL A CG1   1 
ATOM 1308 C CG2   . VAL A 1 206 ? 104.185 141.400 164.740 1.00 163.08 ? 206 VAL A CG2   1 
ATOM 1309 N N     . ARG A 1 207 ? 105.468 145.475 166.869 1.00 166.99 ? 207 ARG A N     1 
ATOM 1310 C CA    . ARG A 1 207 ? 105.525 146.373 168.026 1.00 167.96 ? 207 ARG A CA    1 
ATOM 1311 C C     . ARG A 1 207 ? 104.660 147.621 167.876 1.00 172.54 ? 207 ARG A C     1 
ATOM 1312 O O     . ARG A 1 207 ? 104.344 148.263 168.883 1.00 173.96 ? 207 ARG A O     1 
ATOM 1313 C CB    . ARG A 1 207 ? 106.965 146.815 168.299 1.00 161.82 ? 207 ARG A CB    1 
ATOM 1314 C CG    . ARG A 1 207 ? 107.550 147.704 167.211 1.00 162.62 ? 207 ARG A CG    1 
ATOM 1315 C CD    . ARG A 1 207 ? 109.060 147.826 167.311 1.00 160.30 ? 207 ARG A CD    1 
ATOM 1316 N NE    . ARG A 1 207 ? 109.476 148.716 168.388 1.00 161.03 ? 207 ARG A NE    1 
ATOM 1317 C CZ    . ARG A 1 207 ? 110.714 149.164 168.549 1.00 157.02 ? 207 ARG A CZ    1 
ATOM 1318 N NH1   . ARG A 1 207 ? 111.685 148.824 167.718 1.00 151.19 ? 207 ARG A NH1   1 
ATOM 1319 N NH2   . ARG A 1 207 ? 110.983 149.974 169.569 1.00 157.34 ? 207 ARG A NH2   1 
ATOM 1320 N N     . PHE A 1 208 ? 104.269 147.982 166.656 1.00 172.31 ? 208 PHE A N     1 
ATOM 1321 C CA    . PHE A 1 208 ? 103.437 149.155 166.431 1.00 172.73 ? 208 PHE A CA    1 
ATOM 1322 C C     . PHE A 1 208 ? 101.947 148.841 166.461 1.00 175.42 ? 208 PHE A C     1 
ATOM 1323 O O     . PHE A 1 208 ? 101.134 149.752 166.276 1.00 176.00 ? 208 PHE A O     1 
ATOM 1324 C CB    . PHE A 1 208 ? 103.805 149.812 165.098 1.00 169.94 ? 208 PHE A CB    1 
ATOM 1325 C CG    . PHE A 1 208 ? 105.266 150.129 164.967 1.00 169.26 ? 208 PHE A CG    1 
ATOM 1326 C CD1   . PHE A 1 208 ? 105.871 151.031 165.828 1.00 169.77 ? 208 PHE A CD1   1 
ATOM 1327 C CD2   . PHE A 1 208 ? 106.036 149.524 163.986 1.00 166.82 ? 208 PHE A CD2   1 
ATOM 1328 C CE1   . PHE A 1 208 ? 107.218 151.325 165.713 1.00 166.76 ? 208 PHE A CE1   1 
ATOM 1329 C CE2   . PHE A 1 208 ? 107.383 149.815 163.865 1.00 166.27 ? 208 PHE A CE2   1 
ATOM 1330 C CZ    . PHE A 1 208 ? 107.974 150.716 164.730 1.00 165.65 ? 208 PHE A CZ    1 
ATOM 1331 N N     . PHE A 1 209 ? 101.571 147.584 166.679 1.00 176.64 ? 209 PHE A N     1 
ATOM 1332 C CA    . PHE A 1 209 ? 100.161 147.245 166.815 1.00 177.68 ? 209 PHE A CA    1 
ATOM 1333 C C     . PHE A 1 209 ? 99.636  147.742 168.161 1.00 181.70 ? 209 PHE A C     1 
ATOM 1334 O O     . PHE A 1 209 ? 100.357 147.700 169.163 1.00 182.67 ? 209 PHE A O     1 
ATOM 1335 C CB    . PHE A 1 209 ? 99.938  145.733 166.688 1.00 176.59 ? 209 PHE A CB    1 
ATOM 1336 C CG    . PHE A 1 209 ? 100.314 145.153 165.342 1.00 176.15 ? 209 PHE A CG    1 
ATOM 1337 C CD1   . PHE A 1 209 ? 100.522 145.963 164.232 1.00 175.69 ? 209 PHE A CD1   1 
ATOM 1338 C CD2   . PHE A 1 209 ? 100.451 143.782 165.192 1.00 175.20 ? 209 PHE A CD2   1 
ATOM 1339 C CE1   . PHE A 1 209 ? 100.864 145.418 163.008 1.00 174.26 ? 209 PHE A CE1   1 
ATOM 1340 C CE2   . PHE A 1 209 ? 100.793 143.230 163.970 1.00 173.32 ? 209 PHE A CE2   1 
ATOM 1341 C CZ    . PHE A 1 209 ? 100.999 144.049 162.878 1.00 172.47 ? 209 PHE A CZ    1 
ATOM 1342 N N     . PRO A 1 210 ? 98.390  148.223 168.217 1.00 182.56 ? 210 PRO A N     1 
ATOM 1343 C CA    . PRO A 1 210 ? 97.887  148.807 169.471 1.00 183.42 ? 210 PRO A CA    1 
ATOM 1344 C C     . PRO A 1 210 ? 97.575  147.788 170.554 1.00 185.78 ? 210 PRO A C     1 
ATOM 1345 O O     . PRO A 1 210 ? 97.441  148.181 171.720 1.00 186.37 ? 210 PRO A O     1 
ATOM 1346 C CB    . PRO A 1 210 ? 96.621  149.547 169.025 1.00 180.55 ? 210 PRO A CB    1 
ATOM 1347 C CG    . PRO A 1 210 ? 96.150  148.768 167.844 1.00 179.05 ? 210 PRO A CG    1 
ATOM 1348 C CD    . PRO A 1 210 ? 97.400  148.323 167.130 1.00 178.86 ? 210 PRO A CD    1 
ATOM 1349 N N     . ILE A 1 211 ? 97.451  146.504 170.221 1.00 186.81 ? 211 ILE A N     1 
ATOM 1350 C CA    . ILE A 1 211 ? 97.071  145.499 171.209 1.00 187.21 ? 211 ILE A CA    1 
ATOM 1351 C C     . ILE A 1 211 ? 98.220  145.186 172.164 1.00 188.50 ? 211 ILE A C     1 
ATOM 1352 O O     . ILE A 1 211 ? 99.374  145.548 171.913 1.00 188.79 ? 211 ILE A O     1 
ATOM 1353 C CB    . ILE A 1 211 ? 96.501  144.235 170.524 1.00 185.55 ? 211 ILE A CB    1 
ATOM 1354 C CG1   . ILE A 1 211 ? 97.252  143.828 169.238 1.00 183.71 ? 211 ILE A CG1   1 
ATOM 1355 C CG2   . ILE A 1 211 ? 95.019  144.417 170.227 1.00 183.80 ? 211 ILE A CG2   1 
ATOM 1356 C CD1   . ILE A 1 211 ? 98.708  143.439 169.352 1.00 183.50 ? 211 ILE A CD1   1 
ATOM 1357 N N     . GLU A 1 212 ? 97.899  144.514 173.265 1.00 190.43 ? 212 GLU A N     1 
ATOM 1358 C CA    . GLU A 1 212 ? 98.805  144.313 174.385 1.00 193.00 ? 212 GLU A CA    1 
ATOM 1359 C C     . GLU A 1 212 ? 99.799  143.190 174.058 1.00 193.03 ? 212 GLU A C     1 
ATOM 1360 O O     . GLU A 1 212 ? 99.624  142.430 173.103 1.00 192.87 ? 212 GLU A O     1 
ATOM 1361 C CB    . GLU A 1 212 ? 97.936  144.133 175.657 1.00 194.13 ? 212 GLU A CB    1 
ATOM 1362 C CG    . GLU A 1 212 ? 98.460  143.623 177.034 1.00 196.11 ? 212 GLU A CG    1 
ATOM 1363 C CD    . GLU A 1 212 ? 99.037  142.229 177.046 1.00 196.09 ? 212 GLU A CD    1 
ATOM 1364 O OE1   . GLU A 1 212 ? 98.616  141.424 176.195 1.00 196.24 ? 212 GLU A OE1   1 
ATOM 1365 O OE2   . GLU A 1 212 ? 99.906  141.941 177.896 1.00 196.10 ? 212 GLU A OE2   1 
ATOM 1366 N N     . GLN A 1 213 ? 100.882 143.136 174.846 1.00 193.00 ? 213 GLN A N     1 
ATOM 1367 C CA    . GLN A 1 213 ? 102.074 142.359 174.503 1.00 191.92 ? 213 GLN A CA    1 
ATOM 1368 C C     . GLN A 1 213 ? 101.818 140.856 174.390 1.00 193.05 ? 213 GLN A C     1 
ATOM 1369 O O     . GLN A 1 213 ? 102.527 140.173 173.641 1.00 192.89 ? 213 GLN A O     1 
ATOM 1370 C CB    . GLN A 1 213 ? 103.167 142.613 175.547 1.00 192.14 ? 213 GLN A CB    1 
ATOM 1371 C CG    . GLN A 1 213 ? 103.647 144.064 175.671 1.00 191.54 ? 213 GLN A CG    1 
ATOM 1372 C CD    . GLN A 1 213 ? 104.551 144.528 174.533 1.00 188.24 ? 213 GLN A CD    1 
ATOM 1373 O OE1   . GLN A 1 213 ? 104.741 143.833 173.535 1.00 186.20 ? 213 GLN A OE1   1 
ATOM 1374 N NE2   . GLN A 1 213 ? 105.119 145.719 174.690 1.00 187.71 ? 213 GLN A NE2   1 
ATOM 1375 N N     . SER A 1 214 ? 100.843 140.313 175.130 1.00 194.29 ? 214 SER A N     1 
ATOM 1376 C CA    . SER A 1 214 ? 100.670 138.860 175.155 1.00 193.29 ? 214 SER A CA    1 
ATOM 1377 C C     . SER A 1 214 ? 100.207 138.328 173.803 1.00 193.43 ? 214 SER A C     1 
ATOM 1378 O O     . SER A 1 214 ? 100.757 137.346 173.293 1.00 192.73 ? 214 SER A O     1 
ATOM 1379 C CB    . SER A 1 214 ? 99.692  138.448 176.256 1.00 193.06 ? 214 SER A CB    1 
ATOM 1380 O OG    . SER A 1 214 ? 98.449  139.110 176.107 1.00 194.40 ? 214 SER A OG    1 
ATOM 1381 N N     . GLU A 1 215 ? 99.215  138.978 173.188 1.00 193.83 ? 215 GLU A N     1 
ATOM 1382 C CA    . GLU A 1 215 ? 98.830  138.565 171.844 1.00 190.60 ? 215 GLU A CA    1 
ATOM 1383 C C     . GLU A 1 215 ? 99.895  138.903 170.809 1.00 188.44 ? 215 GLU A C     1 
ATOM 1384 O O     . GLU A 1 215 ? 99.921  138.270 169.751 1.00 186.75 ? 215 GLU A O     1 
ATOM 1385 C CB    . GLU A 1 215 ? 97.470  139.151 171.417 1.00 189.19 ? 215 GLU A CB    1 
ATOM 1386 C CG    . GLU A 1 215 ? 97.164  140.641 171.664 1.00 189.99 ? 215 GLU A CG    1 
ATOM 1387 C CD    . GLU A 1 215 ? 96.927  141.018 173.125 1.00 192.18 ? 215 GLU A CD    1 
ATOM 1388 O OE1   . GLU A 1 215 ? 97.165  140.189 174.028 1.00 194.36 ? 215 GLU A OE1   1 
ATOM 1389 O OE2   . GLU A 1 215 ? 96.484  142.159 173.367 1.00 191.70 ? 215 GLU A OE2   1 
ATOM 1390 N N     . LYS A 1 216 ? 100.798 139.847 171.098 1.00 188.27 ? 216 LYS A N     1 
ATOM 1391 C CA    . LYS A 1 216 ? 101.975 140.004 170.248 1.00 185.66 ? 216 LYS A CA    1 
ATOM 1392 C C     . LYS A 1 216 ? 102.861 138.765 170.309 1.00 185.94 ? 216 LYS A C     1 
ATOM 1393 O O     . LYS A 1 216 ? 103.373 138.310 169.278 1.00 183.62 ? 216 LYS A O     1 
ATOM 1394 C CB    . LYS A 1 216 ? 102.775 141.246 170.643 1.00 184.74 ? 216 LYS A CB    1 
ATOM 1395 C CG    . LYS A 1 216 ? 102.096 142.565 170.346 1.00 182.65 ? 216 LYS A CG    1 
ATOM 1396 C CD    . LYS A 1 216 ? 102.941 143.735 170.817 1.00 181.61 ? 216 LYS A CD    1 
ATOM 1397 C CE    . LYS A 1 216 ? 102.291 145.066 170.482 1.00 178.98 ? 216 LYS A CE    1 
ATOM 1398 N NZ    . LYS A 1 216 ? 102.957 146.200 171.181 1.00 176.19 ? 216 LYS A NZ    1 
ATOM 1399 N N     . ASP A 1 217 ? 103.047 138.197 171.507 1.00 188.75 ? 217 ASP A N     1 
ATOM 1400 C CA    . ASP A 1 217 ? 103.819 136.959 171.619 1.00 187.18 ? 217 ASP A CA    1 
ATOM 1401 C C     . ASP A 1 217 ? 103.112 135.787 170.944 1.00 185.86 ? 217 ASP A C     1 
ATOM 1402 O O     . ASP A 1 217 ? 103.765 134.941 170.325 1.00 184.01 ? 217 ASP A O     1 
ATOM 1403 C CB    . ASP A 1 217 ? 104.114 136.629 173.084 1.00 187.59 ? 217 ASP A CB    1 
ATOM 1404 C CG    . ASP A 1 217 ? 104.463 137.852 173.901 1.00 188.45 ? 217 ASP A CG    1 
ATOM 1405 O OD1   . ASP A 1 217 ? 105.049 138.799 173.334 1.00 188.72 ? 217 ASP A OD1   1 
ATOM 1406 O OD2   . ASP A 1 217 ? 104.154 137.869 175.111 1.00 188.40 ? 217 ASP A OD2   1 
ATOM 1407 N N     . ASN A 1 218 ? 101.783 135.709 171.066 1.00 187.41 ? 218 ASN A N     1 
ATOM 1408 C CA    . ASN A 1 218 ? 101.044 134.658 170.359 1.00 184.97 ? 218 ASN A CA    1 
ATOM 1409 C C     . ASN A 1 218 ? 101.124 134.822 168.843 1.00 183.27 ? 218 ASN A C     1 
ATOM 1410 O O     . ASN A 1 218 ? 101.241 133.828 168.119 1.00 181.95 ? 218 ASN A O     1 
ATOM 1411 C CB    . ASN A 1 218 ? 99.587  134.598 170.821 1.00 186.14 ? 218 ASN A CB    1 
ATOM 1412 C CG    . ASN A 1 218 ? 99.438  134.784 172.313 1.00 187.33 ? 218 ASN A CG    1 
ATOM 1413 O OD1   . ASN A 1 218 ? 100.390 134.592 173.070 1.00 188.10 ? 218 ASN A OD1   1 
ATOM 1414 N ND2   . ASN A 1 218 ? 98.241  135.160 172.749 1.00 186.17 ? 218 ASN A ND2   1 
ATOM 1415 N N     . LEU A 1 219 ? 101.066 136.060 168.344 1.00 184.03 ? 219 LEU A N     1 
ATOM 1416 C CA    . LEU A 1 219 ? 101.251 136.297 166.914 1.00 183.17 ? 219 LEU A CA    1 
ATOM 1417 C C     . LEU A 1 219 ? 102.657 135.916 166.464 1.00 180.60 ? 219 LEU A C     1 
ATOM 1418 O O     . LEU A 1 219 ? 102.836 135.334 165.385 1.00 176.76 ? 219 LEU A O     1 
ATOM 1419 C CB    . LEU A 1 219 ? 100.955 137.761 166.591 1.00 181.59 ? 219 LEU A CB    1 
ATOM 1420 C CG    . LEU A 1 219 ? 101.071 138.200 165.131 1.00 173.46 ? 219 LEU A CG    1 
ATOM 1421 C CD1   . LEU A 1 219 ? 100.041 137.507 164.270 1.00 173.01 ? 219 LEU A CD1   1 
ATOM 1422 C CD2   . LEU A 1 219 ? 100.902 139.704 165.039 1.00 169.51 ? 219 LEU A CD2   1 
ATOM 1423 N N     . LYS A 1 220 ? 103.662 136.233 167.286 1.00 181.11 ? 220 LYS A N     1 
ATOM 1424 C CA    . LYS A 1 220 ? 105.039 135.846 166.995 1.00 177.99 ? 220 LYS A CA    1 
ATOM 1425 C C     . LYS A 1 220 ? 105.183 134.330 166.927 1.00 176.81 ? 220 LYS A C     1 
ATOM 1426 O O     . LYS A 1 220 ? 105.796 133.794 165.996 1.00 175.74 ? 220 LYS A O     1 
ATOM 1427 C CB    . LYS A 1 220 ? 105.964 136.432 168.063 1.00 176.93 ? 220 LYS A CB    1 
ATOM 1428 C CG    . LYS A 1 220 ? 107.445 136.325 167.764 1.00 173.50 ? 220 LYS A CG    1 
ATOM 1429 C CD    . LYS A 1 220 ? 108.262 137.087 168.796 1.00 169.25 ? 220 LYS A CD    1 
ATOM 1430 C CE    . LYS A 1 220 ? 108.303 136.347 170.123 1.00 174.27 ? 220 LYS A CE    1 
ATOM 1431 N NZ    . LYS A 1 220 ? 108.727 137.235 171.240 1.00 175.67 ? 220 LYS A NZ    1 
ATOM 1432 N N     . ASP A 1 221 ? 104.597 133.624 167.897 1.00 179.26 ? 221 ASP A N     1 
ATOM 1433 C CA    . ASP A 1 221 ? 104.655 132.167 167.909 1.00 178.61 ? 221 ASP A CA    1 
ATOM 1434 C C     . ASP A 1 221 ? 103.873 131.563 166.750 1.00 178.41 ? 221 ASP A C     1 
ATOM 1435 O O     . ASP A 1 221 ? 104.225 130.483 166.262 1.00 177.50 ? 221 ASP A O     1 
ATOM 1436 C CB    . ASP A 1 221 ? 104.126 131.632 169.238 1.00 178.64 ? 221 ASP A CB    1 
ATOM 1437 C CG    . ASP A 1 221 ? 105.070 131.901 170.391 1.00 176.26 ? 221 ASP A CG    1 
ATOM 1438 O OD1   . ASP A 1 221 ? 106.240 132.251 170.133 1.00 174.85 ? 221 ASP A OD1   1 
ATOM 1439 O OD2   . ASP A 1 221 ? 104.643 131.763 171.556 1.00 173.70 ? 221 ASP A OD2   1 
ATOM 1440 N N     . ALA A 1 222 ? 102.810 132.235 166.307 1.00 179.44 ? 222 ALA A N     1 
ATOM 1441 C CA    . ALA A 1 222 ? 102.060 131.751 165.156 1.00 178.50 ? 222 ALA A CA    1 
ATOM 1442 C C     . ALA A 1 222 ? 102.850 131.925 163.865 1.00 176.41 ? 222 ALA A C     1 
ATOM 1443 O O     . ALA A 1 222 ? 102.782 131.072 162.972 1.00 177.21 ? 222 ALA A O     1 
ATOM 1444 C CB    . ALA A 1 222 ? 100.715 132.471 165.065 1.00 179.31 ? 222 ALA A CB    1 
ATOM 1445 N N     . VAL A 1 223 ? 103.603 133.017 163.742 1.00 173.87 ? 223 VAL A N     1 
ATOM 1446 C CA    . VAL A 1 223 ? 104.277 133.276 162.474 1.00 170.81 ? 223 VAL A CA    1 
ATOM 1447 C C     . VAL A 1 223 ? 105.632 132.562 162.380 1.00 171.50 ? 223 VAL A C     1 
ATOM 1448 O O     . VAL A 1 223 ? 106.061 132.206 161.277 1.00 168.68 ? 223 VAL A O     1 
ATOM 1449 C CB    . VAL A 1 223 ? 104.407 134.795 162.224 1.00 166.02 ? 223 VAL A CB    1 
ATOM 1450 C CG1   . VAL A 1 223 ? 105.274 135.464 163.263 1.00 167.36 ? 223 VAL A CG1   1 
ATOM 1451 C CG2   . VAL A 1 223 ? 104.887 135.107 160.802 1.00 156.17 ? 223 VAL A CG2   1 
ATOM 1452 N N     . LEU A 1 224 ? 106.313 132.296 163.506 1.00 173.82 ? 224 LEU A N     1 
ATOM 1453 C CA    . LEU A 1 224 ? 107.573 131.562 163.379 1.00 173.26 ? 224 LEU A CA    1 
ATOM 1454 C C     . LEU A 1 224 ? 107.336 130.084 163.085 1.00 173.94 ? 224 LEU A C     1 
ATOM 1455 O O     . LEU A 1 224 ? 108.198 129.428 162.491 1.00 172.24 ? 224 LEU A O     1 
ATOM 1456 C CB    . LEU A 1 224 ? 108.460 131.718 164.625 1.00 173.66 ? 224 LEU A CB    1 
ATOM 1457 C CG    . LEU A 1 224 ? 109.140 132.974 165.197 1.00 174.28 ? 224 LEU A CG    1 
ATOM 1458 C CD1   . LEU A 1 224 ? 109.832 132.766 166.543 1.00 172.41 ? 224 LEU A CD1   1 
ATOM 1459 C CD2   . LEU A 1 224 ? 110.116 133.554 164.182 1.00 173.42 ? 224 LEU A CD2   1 
ATOM 1460 N N     . ASP A 1 225 ? 106.186 129.551 163.490 1.00 175.41 ? 225 ASP A N     1 
ATOM 1461 C CA    . ASP A 1 225 ? 105.823 128.173 163.202 1.00 175.78 ? 225 ASP A CA    1 
ATOM 1462 C C     . ASP A 1 225 ? 105.103 128.139 161.859 1.00 176.68 ? 225 ASP A C     1 
ATOM 1463 O O     . ASP A 1 225 ? 104.266 128.997 161.567 1.00 177.27 ? 225 ASP A O     1 
ATOM 1464 C CB    . ASP A 1 225 ? 104.930 127.613 164.316 1.00 175.65 ? 225 ASP A CB    1 
ATOM 1465 C CG    . ASP A 1 225 ? 104.601 126.127 164.149 1.00 174.70 ? 225 ASP A CG    1 
ATOM 1466 O OD1   . ASP A 1 225 ? 105.016 125.490 163.157 1.00 174.82 ? 225 ASP A OD1   1 
ATOM 1467 O OD2   . ASP A 1 225 ? 103.905 125.588 165.035 1.00 172.51 ? 225 ASP A OD2   1 
ATOM 1468 N N     . LYS A 1 226 ? 105.438 127.141 161.042 1.00 175.80 ? 226 LYS A N     1 
ATOM 1469 C CA    . LYS A 1 226 ? 104.868 127.047 159.704 1.00 174.23 ? 226 LYS A CA    1 
ATOM 1470 C C     . LYS A 1 226 ? 103.452 126.484 159.697 1.00 173.00 ? 226 LYS A C     1 
ATOM 1471 O O     . LYS A 1 226 ? 102.760 126.601 158.680 1.00 171.04 ? 226 LYS A O     1 
ATOM 1472 C CB    . LYS A 1 226 ? 105.776 126.193 158.815 1.00 172.69 ? 226 LYS A CB    1 
ATOM 1473 C CG    . LYS A 1 226 ? 105.708 124.705 159.103 1.00 170.86 ? 226 LYS A CG    1 
ATOM 1474 C CD    . LYS A 1 226 ? 106.966 123.989 158.644 1.00 168.59 ? 226 LYS A CD    1 
ATOM 1475 C CE    . LYS A 1 226 ? 108.192 124.512 159.374 1.00 167.56 ? 226 LYS A CE    1 
ATOM 1476 N NZ    . LYS A 1 226 ? 108.115 124.254 160.839 1.00 166.94 ? 226 LYS A NZ    1 
ATOM 1477 N N     . ASN A 1 227 ? 103.005 125.880 160.800 1.00 172.90 ? 227 ASN A N     1 
ATOM 1478 C CA    . ASN A 1 227 ? 101.677 125.277 160.833 1.00 172.17 ? 227 ASN A CA    1 
ATOM 1479 C C     . ASN A 1 227 ? 100.565 126.307 160.994 1.00 172.92 ? 227 ASN A C     1 
ATOM 1480 O O     . ASN A 1 227 ? 99.441  126.070 160.539 1.00 173.86 ? 227 ASN A O     1 
ATOM 1481 C CB    . ASN A 1 227 ? 101.585 124.256 161.968 1.00 170.97 ? 227 ASN A CB    1 
ATOM 1482 C CG    . ASN A 1 227 ? 102.845 123.434 162.119 1.00 172.58 ? 227 ASN A CG    1 
ATOM 1483 O OD1   . ASN A 1 227 ? 103.635 123.310 161.186 1.00 172.57 ? 227 ASN A OD1   1 
ATOM 1484 N ND2   . ASN A 1 227 ? 103.042 122.868 163.304 1.00 173.72 ? 227 ASN A ND2   1 
ATOM 1485 N N     . ARG A 1 228 ? 100.849 127.444 161.630 1.00 172.62 ? 228 ARG A N     1 
ATOM 1486 C CA    . ARG A 1 228 ? 99.811  128.343 162.125 1.00 172.24 ? 228 ARG A CA    1 
ATOM 1487 C C     . ARG A 1 228 ? 99.570  129.537 161.206 1.00 172.90 ? 228 ARG A C     1 
ATOM 1488 O O     . ARG A 1 228 ? 99.166  130.599 161.687 1.00 174.38 ? 228 ARG A O     1 
ATOM 1489 C CB    . ARG A 1 228 ? 100.144 128.846 163.536 1.00 170.74 ? 228 ARG A CB    1 
ATOM 1490 C CG    . ARG A 1 228 ? 100.969 127.939 164.473 1.00 170.34 ? 228 ARG A CG    1 
ATOM 1491 C CD    . ARG A 1 228 ? 100.411 126.522 164.643 1.00 169.50 ? 228 ARG A CD    1 
ATOM 1492 N NE    . ARG A 1 228 ? 98.986  126.529 164.952 1.00 168.00 ? 228 ARG A NE    1 
ATOM 1493 C CZ    . ARG A 1 228 ? 98.142  125.564 164.613 1.00 167.22 ? 228 ARG A CZ    1 
ATOM 1494 N NH1   . ARG A 1 228 ? 98.545  124.495 163.947 1.00 167.00 ? 228 ARG A NH1   1 
ATOM 1495 N NH2   . ARG A 1 228 ? 96.861  125.675 164.952 1.00 166.83 ? 228 ARG A NH2   1 
ATOM 1496 N N     . ARG A 1 229 ? 99.797  129.385 159.897 1.00 170.90 ? 229 ARG A N     1 
ATOM 1497 C CA    . ARG A 1 229 ? 99.646  130.515 158.981 1.00 170.28 ? 229 ARG A CA    1 
ATOM 1498 C C     . ARG A 1 229 ? 98.190  130.952 158.849 1.00 175.30 ? 229 ARG A C     1 
ATOM 1499 O O     . ARG A 1 229 ? 97.905  132.153 158.746 1.00 176.40 ? 229 ARG A O     1 
ATOM 1500 C CB    . ARG A 1 229 ? 100.219 130.169 157.608 1.00 164.62 ? 229 ARG A CB    1 
ATOM 1501 C CG    . ARG A 1 229 ? 100.462 131.391 156.734 1.00 161.56 ? 229 ARG A CG    1 
ATOM 1502 C CD    . ARG A 1 229 ? 100.846 131.012 155.314 1.00 160.45 ? 229 ARG A CD    1 
ATOM 1503 N NE    . ARG A 1 229 ? 101.376 132.154 154.580 1.00 160.05 ? 229 ARG A NE    1 
ATOM 1504 C CZ    . ARG A 1 229 ? 102.650 132.306 154.245 1.00 162.14 ? 229 ARG A CZ    1 
ATOM 1505 N NH1   . ARG A 1 229 ? 103.562 131.403 154.565 1.00 163.03 ? 229 ARG A NH1   1 
ATOM 1506 N NH2   . ARG A 1 229 ? 103.019 133.394 153.574 1.00 161.51 ? 229 ARG A NH2   1 
ATOM 1507 N N     . GLU A 1 230 ? 97.257  129.993 158.844 1.00 177.17 ? 230 GLU A N     1 
ATOM 1508 C CA    . GLU A 1 230 ? 95.838  130.334 158.765 1.00 178.76 ? 230 GLU A CA    1 
ATOM 1509 C C     . GLU A 1 230 ? 95.387  131.136 159.978 1.00 180.69 ? 230 GLU A C     1 
ATOM 1510 O O     . GLU A 1 230 ? 94.493  131.982 159.871 1.00 182.56 ? 230 GLU A O     1 
ATOM 1511 C CB    . GLU A 1 230 ? 95.000  129.063 158.617 1.00 177.71 ? 230 GLU A CB    1 
ATOM 1512 C CG    . GLU A 1 230 ? 95.440  128.147 157.479 1.00 177.26 ? 230 GLU A CG    1 
ATOM 1513 C CD    . GLU A 1 230 ? 95.632  128.879 156.159 1.00 175.55 ? 230 GLU A CD    1 
ATOM 1514 O OE1   . GLU A 1 230 ? 94.757  129.690 155.780 1.00 176.14 ? 230 GLU A OE1   1 
ATOM 1515 O OE2   . GLU A 1 230 ? 96.663  128.642 155.495 1.00 172.18 ? 230 GLU A OE2   1 
ATOM 1516 N N     . GLU A 1 231 ? 96.018  130.908 161.128 1.00 179.49 ? 231 GLU A N     1 
ATOM 1517 C CA    . GLU A 1 231 ? 95.745  131.723 162.304 1.00 178.50 ? 231 GLU A CA    1 
ATOM 1518 C C     . GLU A 1 231 ? 96.229  133.160 162.101 1.00 179.46 ? 231 GLU A C     1 
ATOM 1519 O O     . GLU A 1 231 ? 95.590  134.114 162.571 1.00 179.88 ? 231 GLU A O     1 
ATOM 1520 C CB    . GLU A 1 231 ? 96.399  131.064 163.517 1.00 175.44 ? 231 GLU A CB    1 
ATOM 1521 C CG    . GLU A 1 231 ? 96.028  131.657 164.844 1.00 176.69 ? 231 GLU A CG    1 
ATOM 1522 C CD    . GLU A 1 231 ? 96.593  130.869 166.010 1.00 177.15 ? 231 GLU A CD    1 
ATOM 1523 O OE1   . GLU A 1 231 ? 97.174  129.789 165.769 1.00 173.15 ? 231 GLU A OE1   1 
ATOM 1524 O OE2   . GLU A 1 231 ? 96.458  131.326 167.165 1.00 179.42 ? 231 GLU A OE2   1 
ATOM 1525 N N     . VAL A 1 232 ? 97.353  133.331 161.392 1.00 178.97 ? 232 VAL A N     1 
ATOM 1526 C CA    . VAL A 1 232 ? 97.819  134.671 161.037 1.00 177.87 ? 232 VAL A CA    1 
ATOM 1527 C C     . VAL A 1 232 ? 96.834  135.352 160.098 1.00 178.05 ? 232 VAL A C     1 
ATOM 1528 O O     . VAL A 1 232 ? 96.557  136.547 160.244 1.00 177.21 ? 232 VAL A O     1 
ATOM 1529 C CB    . VAL A 1 232 ? 99.234  134.630 160.432 1.00 175.14 ? 232 VAL A CB    1 
ATOM 1530 C CG1   . VAL A 1 232 ? 99.890  135.992 160.558 1.00 173.06 ? 232 VAL A CG1   1 
ATOM 1531 C CG2   . VAL A 1 232 ? 100.084 133.605 161.138 1.00 175.39 ? 232 VAL A CG2   1 
ATOM 1532 N N     . LYS A 1 233 ? 96.289  134.612 159.120 1.00 178.56 ? 233 LYS A N     1 
ATOM 1533 C CA    . LYS A 1 233 ? 95.200  135.173 158.315 1.00 178.16 ? 233 LYS A CA    1 
ATOM 1534 C C     . LYS A 1 233 ? 93.982  135.516 159.168 1.00 181.43 ? 233 LYS A C     1 
ATOM 1535 O O     . LYS A 1 233 ? 93.274  136.483 158.865 1.00 182.07 ? 233 LYS A O     1 
ATOM 1536 C CB    . LYS A 1 233 ? 94.761  134.238 157.171 1.00 177.15 ? 233 LYS A CB    1 
ATOM 1537 C CG    . LYS A 1 233 ? 95.743  133.222 156.567 1.00 175.75 ? 233 LYS A CG    1 
ATOM 1538 C CD    . LYS A 1 233 ? 97.067  133.817 156.097 1.00 171.86 ? 233 LYS A CD    1 
ATOM 1539 C CE    . LYS A 1 233 ? 96.847  134.808 154.962 1.00 169.67 ? 233 LYS A CE    1 
ATOM 1540 N NZ    . LYS A 1 233 ? 96.120  134.196 153.816 1.00 167.47 ? 233 LYS A NZ    1 
ATOM 1541 N N     . SER A 1 234 ? 93.730  134.748 160.234 1.00 183.04 ? 234 SER A N     1 
ATOM 1542 C CA    . SER A 1 234 ? 92.589  135.030 161.104 1.00 182.21 ? 234 SER A CA    1 
ATOM 1543 C C     . SER A 1 234 ? 92.740  136.375 161.814 1.00 181.42 ? 234 SER A C     1 
ATOM 1544 O O     . SER A 1 234 ? 91.856  137.238 161.715 1.00 180.41 ? 234 SER A O     1 
ATOM 1545 C CB    . SER A 1 234 ? 92.404  133.900 162.117 1.00 180.91 ? 234 SER A CB    1 
ATOM 1546 O OG    . SER A 1 234 ? 93.223  134.098 163.257 1.00 180.15 ? 234 SER A OG    1 
ATOM 1547 N N     . PHE A 1 235 ? 93.872  136.599 162.501 1.00 180.88 ? 235 PHE A N     1 
ATOM 1548 C CA    . PHE A 1 235 ? 94.049  137.940 163.072 1.00 179.66 ? 235 PHE A CA    1 
ATOM 1549 C C     . PHE A 1 235 ? 94.238  139.013 162.010 1.00 179.34 ? 235 PHE A C     1 
ATOM 1550 O O     . PHE A 1 235 ? 93.948  140.186 162.278 1.00 178.77 ? 235 PHE A O     1 
ATOM 1551 C CB    . PHE A 1 235 ? 95.219  138.101 164.057 1.00 179.37 ? 235 PHE A CB    1 
ATOM 1552 N N     . PHE A 1 236 ? 94.706  138.650 160.818 1.00 178.89 ? 236 PHE A N     1 
ATOM 1553 C CA    . PHE A 1 236 ? 95.010  139.665 159.828 1.00 176.76 ? 236 PHE A CA    1 
ATOM 1554 C C     . PHE A 1 236 ? 93.728  140.170 159.181 1.00 177.43 ? 236 PHE A C     1 
ATOM 1555 O O     . PHE A 1 236 ? 93.657  141.328 158.756 1.00 175.52 ? 236 PHE A O     1 
ATOM 1556 C CB    . PHE A 1 236 ? 95.972  139.081 158.795 1.00 173.89 ? 236 PHE A CB    1 
ATOM 1557 C CG    . PHE A 1 236 ? 96.299  140.022 157.684 1.00 170.35 ? 236 PHE A CG    1 
ATOM 1558 C CD1   . PHE A 1 236 ? 97.236  141.023 157.843 1.00 169.56 ? 236 PHE A CD1   1 
ATOM 1559 C CD2   . PHE A 1 236 ? 95.695  139.861 156.449 1.00 168.80 ? 236 PHE A CD2   1 
ATOM 1560 C CE1   . PHE A 1 236 ? 97.543  141.858 156.800 1.00 168.90 ? 236 PHE A CE1   1 
ATOM 1561 C CE2   . PHE A 1 236 ? 95.998  140.697 155.409 1.00 165.59 ? 236 PHE A CE2   1 
ATOM 1562 C CZ    . PHE A 1 236 ? 96.927  141.693 155.587 1.00 166.48 ? 236 PHE A CZ    1 
ATOM 1563 N N     . ARG A 1 237 ? 92.712  139.307 159.099 1.00 179.28 ? 237 ARG A N     1 
ATOM 1564 C CA    . ARG A 1 237 ? 91.360  139.762 158.802 1.00 178.42 ? 237 ARG A CA    1 
ATOM 1565 C C     . ARG A 1 237 ? 90.735  140.468 159.997 1.00 178.76 ? 237 ARG A C     1 
ATOM 1566 O O     . ARG A 1 237 ? 89.907  141.369 159.815 1.00 178.75 ? 237 ARG A O     1 
ATOM 1567 C CB    . ARG A 1 237 ? 90.483  138.584 158.389 1.00 178.84 ? 237 ARG A CB    1 
ATOM 1568 C CG    . ARG A 1 237 ? 90.811  137.976 157.042 1.00 180.13 ? 237 ARG A CG    1 
ATOM 1569 C CD    . ARG A 1 237 ? 89.698  137.031 156.626 1.00 183.64 ? 237 ARG A CD    1 
ATOM 1570 N NE    . ARG A 1 237 ? 89.680  135.834 157.458 1.00 182.14 ? 237 ARG A NE    1 
ATOM 1571 C CZ    . ARG A 1 237 ? 88.690  135.505 158.278 1.00 180.67 ? 237 ARG A CZ    1 
ATOM 1572 N NH1   . ARG A 1 237 ? 87.614  136.266 158.403 1.00 183.63 ? 237 ARG A NH1   1 
ATOM 1573 N NH2   . ARG A 1 237 ? 88.784  134.389 158.994 1.00 176.39 ? 237 ARG A NH2   1 
ATOM 1574 N N     . LYS A 1 238 ? 91.093  140.053 161.220 1.00 179.38 ? 238 LYS A N     1 
ATOM 1575 C CA    . LYS A 1 238 ? 90.506  140.656 162.414 1.00 178.58 ? 238 LYS A CA    1 
ATOM 1576 C C     . LYS A 1 238 ? 90.877  142.131 162.548 1.00 177.29 ? 238 LYS A C     1 
ATOM 1577 O O     . LYS A 1 238 ? 90.016  142.964 162.858 1.00 176.71 ? 238 LYS A O     1 
ATOM 1578 C CB    . LYS A 1 238 ? 90.936  139.867 163.654 1.00 177.02 ? 238 LYS A CB    1 
ATOM 1579 C CG    . LYS A 1 238 ? 90.889  140.638 164.963 1.00 174.65 ? 238 LYS A CG    1 
ATOM 1580 C CD    . LYS A 1 238 ? 92.297  140.934 165.474 1.00 173.61 ? 238 LYS A CD    1 
ATOM 1581 C CE    . LYS A 1 238 ? 92.271  141.856 166.682 1.00 172.65 ? 238 LYS A CE    1 
ATOM 1582 N NZ    . LYS A 1 238 ? 93.644  142.156 167.183 1.00 171.35 ? 238 LYS A NZ    1 
ATOM 1583 N N     . HIS A 1 239 ? 92.138  142.481 162.303 1.00 176.47 ? 239 HIS A N     1 
ATOM 1584 C CA    . HIS A 1 239 ? 92.587  143.867 162.374 1.00 175.16 ? 239 HIS A CA    1 
ATOM 1585 C C     . HIS A 1 239 ? 93.074  144.282 160.992 1.00 176.08 ? 239 HIS A C     1 
ATOM 1586 O O     . HIS A 1 239 ? 93.953  143.630 160.418 1.00 176.14 ? 239 HIS A O     1 
ATOM 1587 C CB    . HIS A 1 239 ? 93.689  144.041 163.429 1.00 173.89 ? 239 HIS A CB    1 
ATOM 1588 C CG    . HIS A 1 239 ? 93.985  145.470 163.780 1.00 172.68 ? 239 HIS A CG    1 
ATOM 1589 N ND1   . HIS A 1 239 ? 94.169  145.886 165.081 1.00 171.97 ? 239 HIS A ND1   1 
ATOM 1590 C CD2   . HIS A 1 239 ? 94.126  146.575 163.011 1.00 171.92 ? 239 HIS A CD2   1 
ATOM 1591 C CE1   . HIS A 1 239 ? 94.408  147.185 165.099 1.00 170.15 ? 239 HIS A CE1   1 
ATOM 1592 N NE2   . HIS A 1 239 ? 94.388  147.627 163.855 1.00 170.21 ? 239 HIS A NE2   1 
ATOM 1593 N N     . LYS A 1 240 ? 92.517  145.376 160.472 1.00 176.48 ? 240 LYS A N     1 
ATOM 1594 C CA    . LYS A 1 240 ? 92.730  145.797 159.087 1.00 176.70 ? 240 LYS A CA    1 
ATOM 1595 C C     . LYS A 1 240 ? 93.871  146.809 159.035 1.00 177.74 ? 240 LYS A C     1 
ATOM 1596 O O     . LYS A 1 240 ? 93.708  147.967 159.428 1.00 177.50 ? 240 LYS A O     1 
ATOM 1597 C CB    . LYS A 1 240 ? 91.447  146.379 158.503 1.00 175.54 ? 240 LYS A CB    1 
ATOM 1598 N N     . THR A 1 241 ? 95.027  146.364 158.548 1.00 178.38 ? 241 THR A N     1 
ATOM 1599 C CA    . THR A 1 241 ? 96.200  147.194 158.318 1.00 178.16 ? 241 THR A CA    1 
ATOM 1600 C C     . THR A 1 241 ? 96.435  147.364 156.815 1.00 178.08 ? 241 THR A C     1 
ATOM 1601 O O     . THR A 1 241 ? 95.595  146.998 155.987 1.00 178.88 ? 241 THR A O     1 
ATOM 1602 C CB    . THR A 1 241 ? 97.418  146.595 159.023 1.00 175.90 ? 241 THR A CB    1 
ATOM 1603 O OG1   . THR A 1 241 ? 97.569  145.225 158.638 1.00 175.12 ? 241 THR A OG1   1 
ATOM 1604 C CG2   . THR A 1 241 ? 97.251  146.679 160.533 1.00 174.30 ? 241 THR A CG2   1 
ATOM 1605 N N     . ASP A 1 242 ? 97.578  147.952 156.465 1.00 176.94 ? 242 ASP A N     1 
ATOM 1606 C CA    . ASP A 1 242 ? 97.944  148.187 155.074 1.00 175.71 ? 242 ASP A CA    1 
ATOM 1607 C C     . ASP A 1 242 ? 98.282  146.871 154.366 1.00 175.15 ? 242 ASP A C     1 
ATOM 1608 O O     . ASP A 1 242 ? 98.620  145.867 154.995 1.00 174.60 ? 242 ASP A O     1 
ATOM 1609 C CB    . ASP A 1 242 ? 99.134  149.148 155.004 1.00 173.16 ? 242 ASP A CB    1 
ATOM 1610 C CG    . ASP A 1 242 ? 99.385  149.677 153.606 1.00 173.11 ? 242 ASP A CG    1 
ATOM 1611 O OD1   . ASP A 1 242 ? 98.484  149.555 152.749 1.00 173.18 ? 242 ASP A OD1   1 
ATOM 1612 O OD2   . ASP A 1 242 ? 100.487 150.211 153.363 1.00 172.54 ? 242 ASP A OD2   1 
ATOM 1613 N N     . GLU A 1 243 ? 98.146  146.871 153.033 1.00 174.64 ? 243 GLU A N     1 
ATOM 1614 C CA    . GLU A 1 243 ? 98.515  145.692 152.249 1.00 172.13 ? 243 GLU A CA    1 
ATOM 1615 C C     . GLU A 1 243 ? 100.026 145.498 152.213 1.00 170.29 ? 243 GLU A C     1 
ATOM 1616 O O     . GLU A 1 243 ? 100.511 144.367 152.022 1.00 168.54 ? 243 GLU A O     1 
ATOM 1617 C CB    . GLU A 1 243 ? 97.932  145.796 150.836 1.00 171.73 ? 243 GLU A CB    1 
ATOM 1618 C CG    . GLU A 1 243 ? 98.739  146.635 149.856 1.00 171.32 ? 243 GLU A CG    1 
ATOM 1619 C CD    . GLU A 1 243 ? 97.946  147.008 148.619 1.00 170.95 ? 243 GLU A CD    1 
ATOM 1620 O OE1   . GLU A 1 243 ? 97.025  146.249 148.251 1.00 172.10 ? 243 GLU A OE1   1 
ATOM 1621 O OE2   . GLU A 1 243 ? 98.243  148.060 148.015 1.00 169.17 ? 243 GLU A OE2   1 
ATOM 1622 N N     . HIS A 1 244 ? 100.780 146.585 152.419 1.00 170.13 ? 244 HIS A N     1 
ATOM 1623 C CA    . HIS A 1 244 ? 102.215 146.473 152.638 1.00 167.68 ? 244 HIS A CA    1 
ATOM 1624 C C     . HIS A 1 244 ? 102.514 145.615 153.856 1.00 166.80 ? 244 HIS A C     1 
ATOM 1625 O O     . HIS A 1 244 ? 103.519 144.897 153.876 1.00 164.85 ? 244 HIS A O     1 
ATOM 1626 C CB    . HIS A 1 244 ? 102.838 147.861 152.789 1.00 166.81 ? 244 HIS A CB    1 
ATOM 1627 C CG    . HIS A 1 244 ? 102.805 148.678 151.535 1.00 168.73 ? 244 HIS A CG    1 
ATOM 1628 N ND1   . HIS A 1 244 ? 101.633 149.144 150.980 1.00 172.25 ? 244 HIS A ND1   1 
ATOM 1629 C CD2   . HIS A 1 244 ? 103.802 149.109 150.726 1.00 165.91 ? 244 HIS A CD2   1 
ATOM 1630 C CE1   . HIS A 1 244 ? 101.908 149.828 149.884 1.00 170.06 ? 244 HIS A CE1   1 
ATOM 1631 N NE2   . HIS A 1 244 ? 103.217 149.822 149.707 1.00 165.91 ? 244 HIS A NE2   1 
ATOM 1632 N N     . ILE A 1 245 ? 101.627 145.636 154.854 1.00 169.92 ? 245 ILE A N     1 
ATOM 1633 C CA    . ILE A 1 245 ? 101.831 144.819 156.042 1.00 168.21 ? 245 ILE A CA    1 
ATOM 1634 C C     . ILE A 1 245 ? 101.641 143.338 155.716 1.00 167.02 ? 245 ILE A C     1 
ATOM 1635 O O     . ILE A 1 245 ? 102.425 142.500 156.181 1.00 165.71 ? 245 ILE A O     1 
ATOM 1636 C CB    . ILE A 1 245 ? 100.913 145.295 157.183 1.00 168.13 ? 245 ILE A CB    1 
ATOM 1637 C CG1   . ILE A 1 245 ? 101.236 146.744 157.559 1.00 168.64 ? 245 ILE A CG1   1 
ATOM 1638 C CG2   . ILE A 1 245 ? 101.124 144.462 158.429 1.00 166.03 ? 245 ILE A CG2   1 
ATOM 1639 C CD1   . ILE A 1 245 ? 102.720 147.044 157.717 1.00 165.25 ? 245 ILE A CD1   1 
ATOM 1640 N N     . ARG A 1 246 ? 100.634 142.984 154.893 1.00 167.83 ? 246 ARG A N     1 
ATOM 1641 C CA    . ARG A 1 246 ? 100.535 141.587 154.455 1.00 165.22 ? 246 ARG A CA    1 
ATOM 1642 C C     . ARG A 1 246 ? 101.767 141.145 153.681 1.00 162.58 ? 246 ARG A C     1 
ATOM 1643 O O     . ARG A 1 246 ? 102.342 140.091 153.983 1.00 161.11 ? 246 ARG A O     1 
ATOM 1644 C CB    . ARG A 1 246 ? 99.292  141.261 153.608 1.00 165.17 ? 246 ARG A CB    1 
ATOM 1645 N N     . LYS A 1 247 ? 102.187 141.924 152.674 1.00 162.25 ? 247 LYS A N     1 
ATOM 1646 C CA    . LYS A 1 247 ? 103.295 141.440 151.850 1.00 161.28 ? 247 LYS A CA    1 
ATOM 1647 C C     . LYS A 1 247 ? 104.591 141.368 152.654 1.00 161.31 ? 247 LYS A C     1 
ATOM 1648 O O     . LYS A 1 247 ? 105.349 140.401 152.521 1.00 160.95 ? 247 LYS A O     1 
ATOM 1649 C CB    . LYS A 1 247 ? 103.470 142.289 150.589 1.00 161.81 ? 247 LYS A CB    1 
ATOM 1650 C CG    . LYS A 1 247 ? 103.654 143.766 150.799 1.00 162.59 ? 247 LYS A CG    1 
ATOM 1651 C CD    . LYS A 1 247 ? 104.644 144.348 149.803 1.00 161.20 ? 247 LYS A CD    1 
ATOM 1652 C CE    . LYS A 1 247 ? 105.024 145.774 150.168 1.00 159.44 ? 247 LYS A CE    1 
ATOM 1653 N NZ    . LYS A 1 247 ? 106.111 146.298 149.297 1.00 148.31 ? 247 LYS A NZ    1 
ATOM 1654 N N     . GLN A 1 248 ? 104.811 142.322 153.566 1.00 162.10 ? 248 GLN A N     1 
ATOM 1655 C CA    . GLN A 1 248 ? 105.996 142.283 154.416 1.00 160.81 ? 248 GLN A CA    1 
ATOM 1656 C C     . GLN A 1 248 ? 105.974 141.087 155.364 1.00 159.03 ? 248 GLN A C     1 
ATOM 1657 O O     . GLN A 1 248 ? 106.924 140.294 155.383 1.00 157.49 ? 248 GLN A O     1 
ATOM 1658 C CB    . GLN A 1 248 ? 106.111 143.591 155.198 1.00 162.09 ? 248 GLN A CB    1 
ATOM 1659 C CG    . GLN A 1 248 ? 106.828 144.698 154.444 1.00 160.50 ? 248 GLN A CG    1 
ATOM 1660 C CD    . GLN A 1 248 ? 106.462 146.077 154.953 1.00 162.57 ? 248 GLN A CD    1 
ATOM 1661 O OE1   . GLN A 1 248 ? 105.843 146.217 156.007 1.00 163.02 ? 248 GLN A OE1   1 
ATOM 1662 N NE2   . GLN A 1 248 ? 106.841 147.106 154.204 1.00 161.71 ? 248 GLN A NE2   1 
ATOM 1663 N N     . VAL A 1 249 ? 104.885 140.924 156.132 1.00 159.17 ? 249 VAL A N     1 
ATOM 1664 C CA    . VAL A 1 249 ? 104.818 139.870 157.145 1.00 157.04 ? 249 VAL A CA    1 
ATOM 1665 C C     . VAL A 1 249 ? 104.908 138.496 156.498 1.00 157.42 ? 249 VAL A C     1 
ATOM 1666 O O     . VAL A 1 249 ? 105.644 137.617 156.967 1.00 156.00 ? 249 VAL A O     1 
ATOM 1667 C CB    . VAL A 1 249 ? 103.535 140.018 157.987 1.00 155.87 ? 249 VAL A CB    1 
ATOM 1668 C CG1   . VAL A 1 249 ? 103.284 138.770 158.822 1.00 155.16 ? 249 VAL A CG1   1 
ATOM 1669 C CG2   . VAL A 1 249 ? 103.642 141.220 158.896 1.00 156.35 ? 249 VAL A CG2   1 
ATOM 1670 N N     . TYR A 1 250 ? 104.208 138.301 155.384 1.00 159.84 ? 250 TYR A N     1 
ATOM 1671 C CA    . TYR A 1 250 ? 104.297 137.015 154.718 1.00 159.96 ? 250 TYR A CA    1 
ATOM 1672 C C     . TYR A 1 250 ? 105.583 136.877 153.910 1.00 159.69 ? 250 TYR A C     1 
ATOM 1673 O O     . TYR A 1 250 ? 105.880 135.777 153.433 1.00 159.83 ? 250 TYR A O     1 
ATOM 1674 C CB    . TYR A 1 250 ? 103.048 136.814 153.858 1.00 160.32 ? 250 TYR A CB    1 
ATOM 1675 C CG    . TYR A 1 250 ? 101.814 136.719 154.733 1.00 161.27 ? 250 TYR A CG    1 
ATOM 1676 C CD1   . TYR A 1 250 ? 101.791 135.882 155.842 1.00 162.44 ? 250 TYR A CD1   1 
ATOM 1677 C CD2   . TYR A 1 250 ? 100.692 137.500 154.481 1.00 162.36 ? 250 TYR A CD2   1 
ATOM 1678 C CE1   . TYR A 1 250 ? 100.680 135.810 156.663 1.00 164.66 ? 250 TYR A CE1   1 
ATOM 1679 C CE2   . TYR A 1 250 ? 99.577  137.435 155.296 1.00 164.54 ? 250 TYR A CE2   1 
ATOM 1680 C CZ    . TYR A 1 250 ? 99.577  136.587 156.384 1.00 167.35 ? 250 TYR A CZ    1 
ATOM 1681 O OH    . TYR A 1 250 ? 98.471  136.520 157.199 1.00 171.32 ? 250 TYR A OH    1 
ATOM 1682 N N     . ASP A 1 251 ? 106.355 137.962 153.755 1.00 159.33 ? 251 ASP A N     1 
ATOM 1683 C CA    . ASP A 1 251 ? 107.723 137.831 153.264 1.00 157.75 ? 251 ASP A CA    1 
ATOM 1684 C C     . ASP A 1 251 ? 108.661 137.288 154.341 1.00 155.63 ? 251 ASP A C     1 
ATOM 1685 O O     . ASP A 1 251 ? 109.534 136.466 154.035 1.00 154.56 ? 251 ASP A O     1 
ATOM 1686 C CB    . ASP A 1 251 ? 108.220 139.174 152.728 1.00 157.83 ? 251 ASP A CB    1 
ATOM 1687 N N     . ILE A 1 252 ? 108.525 137.740 155.599 1.00 155.14 ? 252 ILE A N     1 
ATOM 1688 C CA    . ILE A 1 252 ? 109.314 137.047 156.634 1.00 152.69 ? 252 ILE A CA    1 
ATOM 1689 C C     . ILE A 1 252 ? 108.802 135.617 156.810 1.00 151.34 ? 252 ILE A C     1 
ATOM 1690 O O     . ILE A 1 252 ? 109.587 134.700 157.087 1.00 148.52 ? 252 ILE A O     1 
ATOM 1691 C CB    . ILE A 1 252 ? 109.432 137.725 158.031 1.00 148.50 ? 252 ILE A CB    1 
ATOM 1692 C CG1   . ILE A 1 252 ? 109.673 139.240 158.054 1.00 148.10 ? 252 ILE A CG1   1 
ATOM 1693 C CG2   . ILE A 1 252 ? 110.564 137.112 158.853 1.00 141.23 ? 252 ILE A CG2   1 
ATOM 1694 C CD1   . ILE A 1 252 ? 108.497 140.091 157.976 1.00 150.65 ? 252 ILE A CD1   1 
ATOM 1695 N N     . ALA A 1 253 ? 107.497 135.391 156.622 1.00 152.22 ? 253 ALA A N     1 
ATOM 1696 C CA    . ALA A 1 253 ? 106.963 134.034 156.718 1.00 151.55 ? 253 ALA A CA    1 
ATOM 1697 C C     . ALA A 1 253 ? 107.524 133.116 155.635 1.00 150.95 ? 253 ALA A C     1 
ATOM 1698 O O     . ALA A 1 253 ? 107.578 131.896 155.826 1.00 146.53 ? 253 ALA A O     1 
ATOM 1699 C CB    . ALA A 1 253 ? 105.437 134.061 156.650 1.00 153.99 ? 253 ALA A CB    1 
ATOM 1700 N N     . ASP A 1 254 ? 107.952 133.675 154.502 1.00 154.62 ? 254 ASP A N     1 
ATOM 1701 C CA    . ASP A 1 254 ? 108.547 132.896 153.424 1.00 155.00 ? 254 ASP A CA    1 
ATOM 1702 C C     . ASP A 1 254 ? 110.056 133.079 153.302 1.00 152.33 ? 254 ASP A C     1 
ATOM 1703 O O     . ASP A 1 254 ? 110.649 132.525 152.370 1.00 151.20 ? 254 ASP A O     1 
ATOM 1704 C CB    . ASP A 1 254 ? 107.874 133.236 152.089 1.00 159.54 ? 254 ASP A CB    1 
ATOM 1705 C CG    . ASP A 1 254 ? 106.375 133.005 152.117 1.00 160.88 ? 254 ASP A CG    1 
ATOM 1706 O OD1   . ASP A 1 254 ? 105.912 132.195 152.947 1.00 161.77 ? 254 ASP A OD1   1 
ATOM 1707 O OD2   . ASP A 1 254 ? 105.658 133.638 151.314 1.00 161.03 ? 254 ASP A OD2   1 
ATOM 1708 N N     . ASN A 1 255 ? 110.676 133.829 154.222 1.00 150.28 ? 255 ASN A N     1 
ATOM 1709 C CA    . ASN A 1 255 ? 112.130 134.011 154.403 1.00 147.72 ? 255 ASN A CA    1 
ATOM 1710 C C     . ASN A 1 255 ? 112.873 134.283 153.088 1.00 146.83 ? 255 ASN A C     1 
ATOM 1711 O O     . ASN A 1 255 ? 113.721 133.511 152.637 1.00 146.59 ? 255 ASN A O     1 
ATOM 1712 C CB    . ASN A 1 255 ? 112.765 132.836 155.172 1.00 145.45 ? 255 ASN A CB    1 
ATOM 1713 C CG    . ASN A 1 255 ? 112.501 131.471 154.546 1.00 147.33 ? 255 ASN A CG    1 
ATOM 1714 O OD1   . ASN A 1 255 ? 111.728 130.675 155.078 1.00 144.21 ? 255 ASN A OD1   1 
ATOM 1715 N ND2   . ASN A 1 255 ? 113.153 131.192 153.424 1.00 149.92 ? 255 ASN A ND2   1 
ATOM 1716 N N     . LYS A 1 256 ? 112.538 135.421 152.485 1.00 146.86 ? 256 LYS A N     1 
ATOM 1717 C CA    . LYS A 1 256 ? 113.329 135.926 151.374 1.00 145.24 ? 256 LYS A CA    1 
ATOM 1718 C C     . LYS A 1 256 ? 114.562 136.649 151.912 1.00 140.63 ? 256 LYS A C     1 
ATOM 1719 O O     . LYS A 1 256 ? 114.751 136.795 153.124 1.00 137.17 ? 256 LYS A O     1 
ATOM 1720 C CB    . LYS A 1 256 ? 112.484 136.834 150.483 1.00 145.89 ? 256 LYS A CB    1 
ATOM 1721 N N     . LEU A 1 257 ? 115.421 137.110 150.999 1.00 140.49 ? 257 LEU A N     1 
ATOM 1722 C CA    . LEU A 1 257 ? 116.680 137.748 151.386 1.00 138.33 ? 257 LEU A CA    1 
ATOM 1723 C C     . LEU A 1 257 ? 116.326 139.167 151.847 1.00 139.07 ? 257 LEU A C     1 
ATOM 1724 O O     . LEU A 1 257 ? 116.351 140.143 151.095 1.00 136.63 ? 257 LEU A O     1 
ATOM 1725 C CB    . LEU A 1 257 ? 117.680 137.706 150.233 1.00 135.94 ? 257 LEU A CB    1 
ATOM 1726 C CG    . LEU A 1 257 ? 119.026 138.442 150.280 1.00 137.41 ? 257 LEU A CG    1 
ATOM 1727 C CD1   . LEU A 1 257 ? 119.710 138.272 151.627 1.00 131.08 ? 257 LEU A CD1   1 
ATOM 1728 C CD2   . LEU A 1 257 ? 119.940 137.984 149.153 1.00 138.08 ? 257 LEU A CD2   1 
ATOM 1729 N N     . SER A 1 258 ? 115.929 139.254 153.119 1.00 140.07 ? 258 SER A N     1 
ATOM 1730 C CA    . SER A 1 258 ? 115.698 140.527 153.784 1.00 137.40 ? 258 SER A CA    1 
ATOM 1731 C C     . SER A 1 258 ? 116.430 140.613 155.113 1.00 131.57 ? 258 SER A C     1 
ATOM 1732 O O     . SER A 1 258 ? 116.507 141.704 155.687 1.00 128.76 ? 258 SER A O     1 
ATOM 1733 C CB    . SER A 1 258 ? 114.202 140.776 154.027 1.00 138.19 ? 258 SER A CB    1 
ATOM 1734 O OG    . SER A 1 258 ? 113.574 139.644 154.603 1.00 135.82 ? 258 SER A OG    1 
ATOM 1735 N N     . GLY A 1 259 ? 116.967 139.503 155.612 1.00 125.42 ? 259 GLY A N     1 
ATOM 1736 C CA    . GLY A 1 259 ? 117.664 139.446 156.875 1.00 112.09 ? 259 GLY A CA    1 
ATOM 1737 C C     . GLY A 1 259 ? 119.087 139.942 156.861 1.00 115.74 ? 259 GLY A C     1 
ATOM 1738 O O     . GLY A 1 259 ? 119.733 139.972 157.912 1.00 118.19 ? 259 GLY A O     1 
ATOM 1739 N N     . ARG A 1 260 ? 119.607 140.321 155.695 1.00 117.15 ? 260 ARG A N     1 
ATOM 1740 C CA    . ARG A 1 260 ? 120.946 140.882 155.599 1.00 111.19 ? 260 ARG A CA    1 
ATOM 1741 C C     . ARG A 1 260 ? 120.916 142.400 155.479 1.00 113.76 ? 260 ARG A C     1 
ATOM 1742 O O     . ARG A 1 260 ? 121.785 143.076 156.041 1.00 108.56 ? 260 ARG A O     1 
ATOM 1743 C CB    . ARG A 1 260 ? 121.692 140.249 154.409 1.00 101.35 ? 260 ARG A CB    1 
ATOM 1744 C CG    . ARG A 1 260 ? 122.973 140.944 153.959 1.00 89.17  ? 260 ARG A CG    1 
ATOM 1745 C CD    . ARG A 1 260 ? 124.014 140.951 155.074 1.00 77.30  ? 260 ARG A CD    1 
ATOM 1746 N NE    . ARG A 1 260 ? 124.740 139.695 155.195 1.00 62.97  ? 260 ARG A NE    1 
ATOM 1747 C CZ    . ARG A 1 260 ? 125.979 139.593 155.647 1.00 55.18  ? 260 ARG A CZ    1 
ATOM 1748 N NH1   . ARG A 1 260 ? 126.660 140.656 156.031 1.00 56.08  ? 260 ARG A NH1   1 
ATOM 1749 N NH2   . ARG A 1 260 ? 126.544 138.394 155.719 1.00 53.68  ? 260 ARG A NH2   1 
ATOM 1750 N N     . THR A 1 261 ? 119.902 142.953 154.815 1.00 119.90 ? 261 THR A N     1 
ATOM 1751 C CA    . THR A 1 261 ? 119.735 144.403 154.747 1.00 123.03 ? 261 THR A CA    1 
ATOM 1752 C C     . THR A 1 261 ? 119.229 144.670 156.159 1.00 120.05 ? 261 THR A C     1 
ATOM 1753 O O     . THR A 1 261 ? 118.050 144.474 156.463 1.00 122.39 ? 261 THR A O     1 
ATOM 1754 C CB    . THR A 1 261 ? 118.760 144.783 153.641 1.00 123.84 ? 261 THR A CB    1 
ATOM 1755 O OG1   . THR A 1 261 ? 119.083 144.057 152.447 1.00 122.46 ? 261 THR A OG1   1 
ATOM 1756 C CG2   . THR A 1 261 ? 118.818 146.277 153.369 1.00 122.62 ? 261 THR A CG2   1 
ATOM 1757 N N     . VAL A 1 262 ? 120.121 145.173 157.010 1.00 112.70 ? 262 VAL A N     1 
ATOM 1758 C CA    . VAL A 1 262 ? 119.890 145.283 158.451 1.00 113.59 ? 262 VAL A CA    1 
ATOM 1759 C C     . VAL A 1 262 ? 121.054 146.071 159.033 1.00 115.71 ? 262 VAL A C     1 
ATOM 1760 O O     . VAL A 1 262 ? 122.148 146.096 158.456 1.00 114.80 ? 262 VAL A O     1 
ATOM 1761 C CB    . VAL A 1 262 ? 119.681 143.952 159.229 1.00 112.50 ? 262 VAL A CB    1 
ATOM 1762 C CG1   . VAL A 1 262 ? 118.474 143.132 158.768 1.00 112.36 ? 262 VAL A CG1   1 
ATOM 1763 C CG2   . VAL A 1 262 ? 120.953 143.102 159.196 1.00 110.16 ? 262 VAL A CG2   1 
ATOM 1764 N N     . PHE A 1 263 ? 120.821 146.730 160.167 1.00 116.07 ? 263 PHE A N     1 
ATOM 1765 C CA    . PHE A 1 263 ? 121.887 147.376 160.921 1.00 111.97 ? 263 PHE A CA    1 
ATOM 1766 C C     . PHE A 1 263 ? 122.500 146.361 161.886 1.00 113.03 ? 263 PHE A C     1 
ATOM 1767 O O     . PHE A 1 263 ? 122.266 145.156 161.778 1.00 113.02 ? 263 PHE A O     1 
ATOM 1768 C CB    . PHE A 1 263 ? 121.372 148.598 161.680 1.00 111.94 ? 263 PHE A CB    1 
ATOM 1769 C CG    . PHE A 1 263 ? 120.810 149.694 160.820 1.00 112.89 ? 263 PHE A CG    1 
ATOM 1770 C CD1   . PHE A 1 263 ? 121.091 149.784 159.467 1.00 114.17 ? 263 PHE A CD1   1 
ATOM 1771 C CD2   . PHE A 1 263 ? 119.976 150.638 161.390 1.00 112.12 ? 263 PHE A CD2   1 
ATOM 1772 C CE1   . PHE A 1 263 ? 120.571 150.812 158.707 1.00 116.51 ? 263 PHE A CE1   1 
ATOM 1773 C CE2   . PHE A 1 263 ? 119.445 151.662 160.637 1.00 113.61 ? 263 PHE A CE2   1 
ATOM 1774 C CZ    . PHE A 1 263 ? 119.744 151.749 159.289 1.00 116.75 ? 263 PHE A CZ    1 
ATOM 1775 N N     . CYS A 1 264 ? 123.320 146.830 162.822 1.00 115.42 ? 264 CYS A N     1 
ATOM 1776 C CA    . CYS A 1 264 ? 123.791 145.969 163.896 1.00 117.28 ? 264 CYS A CA    1 
ATOM 1777 C C     . CYS A 1 264 ? 122.646 145.639 164.843 1.00 117.25 ? 264 CYS A C     1 
ATOM 1778 O O     . CYS A 1 264 ? 121.742 146.452 165.049 1.00 119.30 ? 264 CYS A O     1 
ATOM 1779 C CB    . CYS A 1 264 ? 124.937 146.641 164.647 1.00 112.81 ? 264 CYS A CB    1 
ATOM 1780 S SG    . CYS A 1 264 ? 124.717 148.410 164.908 1.00 104.89 ? 264 CYS A SG    1 
ATOM 1781 N N     . LYS A 1 265 ? 122.712 144.438 165.440 1.00 113.12 ? 265 LYS A N     1 
ATOM 1782 C CA    . LYS A 1 265 ? 121.563 143.854 166.135 1.00 110.47 ? 265 LYS A CA    1 
ATOM 1783 C C     . LYS A 1 265 ? 121.094 144.698 167.310 1.00 116.89 ? 265 LYS A C     1 
ATOM 1784 O O     . LYS A 1 265 ? 119.910 144.659 167.664 1.00 118.80 ? 265 LYS A O     1 
ATOM 1785 C CB    . LYS A 1 265 ? 121.895 142.445 166.624 1.00 105.19 ? 265 LYS A CB    1 
ATOM 1786 C CG    . LYS A 1 265 ? 121.956 141.407 165.527 1.00 104.39 ? 265 LYS A CG    1 
ATOM 1787 C CD    . LYS A 1 265 ? 122.585 140.117 166.029 1.00 103.40 ? 265 LYS A CD    1 
ATOM 1788 C CE    . LYS A 1 265 ? 122.534 139.020 164.969 1.00 104.37 ? 265 LYS A CE    1 
ATOM 1789 N NZ    . LYS A 1 265 ? 123.428 137.866 165.289 1.00 99.87  ? 265 LYS A NZ    1 
ATOM 1790 N N     . GLU A 1 266 ? 121.996 145.461 167.926 1.00 119.47 ? 266 GLU A N     1 
ATOM 1791 C CA    . GLU A 1 266 ? 121.617 146.270 169.077 1.00 121.54 ? 266 GLU A CA    1 
ATOM 1792 C C     . GLU A 1 266 ? 120.774 147.477 168.703 1.00 123.31 ? 266 GLU A C     1 
ATOM 1793 O O     . GLU A 1 266 ? 120.111 148.038 169.580 1.00 127.68 ? 266 GLU A O     1 
ATOM 1794 C CB    . GLU A 1 266 ? 122.857 146.736 169.849 1.00 119.34 ? 266 GLU A CB    1 
ATOM 1795 C CG    . GLU A 1 266 ? 123.681 145.630 170.513 1.00 117.29 ? 266 GLU A CG    1 
ATOM 1796 C CD    . GLU A 1 266 ? 124.603 144.905 169.558 1.00 121.10 ? 266 GLU A CD    1 
ATOM 1797 O OE1   . GLU A 1 266 ? 124.696 145.334 168.390 1.00 122.23 ? 266 GLU A OE1   1 
ATOM 1798 O OE2   . GLU A 1 266 ? 125.236 143.913 169.979 1.00 122.35 ? 266 GLU A OE2   1 
ATOM 1799 N N     . HIS A 1 267 ? 120.769 147.880 167.434 1.00 121.52 ? 267 HIS A N     1 
ATOM 1800 C CA    . HIS A 1 267 ? 119.967 149.016 166.995 1.00 123.73 ? 267 HIS A CA    1 
ATOM 1801 C C     . HIS A 1 267 ? 119.049 148.676 165.829 1.00 125.36 ? 267 HIS A C     1 
ATOM 1802 O O     . HIS A 1 267 ? 118.730 149.559 165.028 1.00 124.41 ? 267 HIS A O     1 
ATOM 1803 C CB    . HIS A 1 267 ? 120.850 150.212 166.647 1.00 120.87 ? 267 HIS A CB    1 
ATOM 1804 C CG    . HIS A 1 267 ? 122.130 150.256 167.415 1.00 120.78 ? 267 HIS A CG    1 
ATOM 1805 N ND1   . HIS A 1 267 ? 123.370 150.146 166.815 1.00 120.64 ? 267 HIS A ND1   1 
ATOM 1806 C CD2   . HIS A 1 267 ? 122.365 150.434 168.736 1.00 121.82 ? 267 HIS A CD2   1 
ATOM 1807 C CE1   . HIS A 1 267 ? 124.310 150.246 167.736 1.00 120.80 ? 267 HIS A CE1   1 
ATOM 1808 N NE2   . HIS A 1 267 ? 123.726 150.404 168.912 1.00 121.90 ? 267 HIS A NE2   1 
ATOM 1809 N N     . ILE A 1 268 ? 118.629 147.417 165.706 1.00 126.58 ? 268 ILE A N     1 
ATOM 1810 C CA    . ILE A 1 268 ? 117.432 147.129 164.922 1.00 129.28 ? 268 ILE A CA    1 
ATOM 1811 C C     . ILE A 1 268 ? 116.215 147.758 165.582 1.00 133.12 ? 268 ILE A C     1 
ATOM 1812 O O     . ILE A 1 268 ? 115.310 148.258 164.903 1.00 135.51 ? 268 ILE A O     1 
ATOM 1813 C CB    . ILE A 1 268 ? 117.246 145.612 164.716 1.00 127.80 ? 268 ILE A CB    1 
ATOM 1814 C CG1   . ILE A 1 268 ? 118.525 144.902 164.255 1.00 122.28 ? 268 ILE A CG1   1 
ATOM 1815 C CG2   . ILE A 1 268 ? 116.164 145.351 163.692 1.00 131.64 ? 268 ILE A CG2   1 
ATOM 1816 C CD1   . ILE A 1 268 ? 119.275 145.601 163.128 1.00 119.78 ? 268 ILE A CD1   1 
ATOM 1817 N N     . LEU A 1 269 ? 116.178 147.751 166.911 1.00 132.73 ? 269 LEU A N     1 
ATOM 1818 C CA    . LEU A 1 269 ? 115.116 148.408 167.660 1.00 134.12 ? 269 LEU A CA    1 
ATOM 1819 C C     . LEU A 1 269 ? 115.213 149.922 167.515 1.00 133.39 ? 269 LEU A C     1 
ATOM 1820 O O     . LEU A 1 269 ? 116.304 150.489 167.490 1.00 127.83 ? 269 LEU A O     1 
ATOM 1821 C CB    . LEU A 1 269 ? 115.170 148.024 169.143 1.00 133.79 ? 269 LEU A CB    1 
ATOM 1822 C CG    . LEU A 1 269 ? 115.046 146.554 169.566 1.00 132.12 ? 269 LEU A CG    1 
ATOM 1823 C CD1   . LEU A 1 269 ? 114.022 145.820 168.708 1.00 131.70 ? 269 LEU A CD1   1 
ATOM 1824 C CD2   . LEU A 1 269 ? 116.390 145.820 169.598 1.00 127.95 ? 269 LEU A CD2   1 
ATOM 1825 N N     . SER A 1 807 ? 135.543 154.695 128.156 1.00 117.44 ? 548 SER A N     1 
ATOM 1826 C CA    . SER A 1 807 ? 136.310 153.798 127.299 1.00 117.84 ? 548 SER A CA    1 
ATOM 1827 C C     . SER A 1 807 ? 137.794 153.835 127.651 1.00 118.07 ? 548 SER A C     1 
ATOM 1828 O O     . SER A 1 807 ? 138.237 154.707 128.401 1.00 117.88 ? 548 SER A O     1 
ATOM 1829 C CB    . SER A 1 807 ? 136.108 154.162 125.826 1.00 117.99 ? 548 SER A CB    1 
ATOM 1830 O OG    . SER A 1 807 ? 136.577 155.471 125.555 1.00 117.72 ? 548 SER A OG    1 
ATOM 1831 N N     . ARG A 1 808 ? 138.539 152.862 127.115 1.00 115.27 ? 549 ARG A N     1 
ATOM 1832 C CA    . ARG A 1 808 ? 139.986 152.710 127.292 1.00 113.39 ? 549 ARG A CA    1 
ATOM 1833 C C     . ARG A 1 808 ? 140.394 152.551 128.755 1.00 110.61 ? 549 ARG A C     1 
ATOM 1834 O O     . ARG A 1 808 ? 141.539 152.840 129.117 1.00 108.11 ? 549 ARG A O     1 
ATOM 1835 C CB    . ARG A 1 808 ? 140.757 153.876 126.655 1.00 112.36 ? 549 ARG A CB    1 
ATOM 1836 C CG    . ARG A 1 808 ? 140.463 154.088 125.179 1.00 108.19 ? 549 ARG A CG    1 
ATOM 1837 C CD    . ARG A 1 808 ? 141.266 155.252 124.619 1.00 106.69 ? 549 ARG A CD    1 
ATOM 1838 N NE    . ARG A 1 808 ? 140.893 155.562 123.244 1.00 104.06 ? 549 ARG A NE    1 
ATOM 1839 C CZ    . ARG A 1 808 ? 141.584 155.185 122.177 1.00 105.25 ? 549 ARG A CZ    1 
ATOM 1840 N NH1   . ARG A 1 808 ? 142.702 154.487 122.288 1.00 104.87 ? 549 ARG A NH1   1 
ATOM 1841 N NH2   . ARG A 1 808 ? 141.142 155.519 120.968 1.00 103.51 ? 549 ARG A NH2   1 
ATOM 1842 N N     . GLY A 1 809 ? 139.480 152.099 129.611 1.00 103.62 ? 550 GLY A N     1 
ATOM 1843 C CA    . GLY A 1 809 ? 139.794 151.916 131.013 1.00 93.75  ? 550 GLY A CA    1 
ATOM 1844 C C     . GLY A 1 809 ? 140.346 150.548 131.353 1.00 86.72  ? 550 GLY A C     1 
ATOM 1845 O O     . GLY A 1 809 ? 141.461 150.437 131.871 1.00 81.73  ? 550 GLY A O     1 
ATOM 1846 N N     . SER A 1 810 ? 139.577 149.499 131.073 1.00 80.39  ? 551 SER A N     1 
ATOM 1847 C CA    . SER A 1 810 ? 140.017 148.151 131.417 1.00 73.64  ? 551 SER A CA    1 
ATOM 1848 C C     . SER A 1 810 ? 139.924 147.161 130.266 1.00 64.79  ? 551 SER A C     1 
ATOM 1849 O O     . SER A 1 810 ? 140.789 146.293 130.149 1.00 67.78  ? 551 SER A O     1 
ATOM 1850 C CB    . SER A 1 810 ? 139.212 147.624 132.609 1.00 74.45  ? 551 SER A CB    1 
ATOM 1851 O OG    . SER A 1 810 ? 139.391 148.453 133.744 1.00 86.33  ? 551 SER A OG    1 
ATOM 1852 N N     . ALA A 1 811 ? 138.901 147.261 129.423 1.00 60.78  ? 552 ALA A N     1 
ATOM 1853 C CA    . ALA A 1 811 ? 138.715 146.288 128.356 1.00 57.50  ? 552 ALA A CA    1 
ATOM 1854 C C     . ALA A 1 811 ? 139.723 146.512 127.237 1.00 62.72  ? 552 ALA A C     1 
ATOM 1855 O O     . ALA A 1 811 ? 140.180 147.633 126.997 1.00 70.37  ? 552 ALA A O     1 
ATOM 1856 C CB    . ALA A 1 811 ? 137.294 146.361 127.799 1.00 53.40  ? 552 ALA A CB    1 
ATOM 1857 N N     . LEU A 1 812 ? 140.074 145.425 126.555 1.00 59.31  ? 553 LEU A N     1 
ATOM 1858 C CA    . LEU A 1 812 ? 141.056 145.451 125.478 1.00 56.96  ? 553 LEU A CA    1 
ATOM 1859 C C     . LEU A 1 812 ? 140.457 145.130 124.119 1.00 57.80  ? 553 LEU A C     1 
ATOM 1860 O O     . LEU A 1 812 ? 140.726 145.834 123.142 1.00 64.66  ? 553 LEU A O     1 
ATOM 1861 C CB    . LEU A 1 812 ? 142.203 144.468 125.769 1.00 53.20  ? 553 LEU A CB    1 
ATOM 1862 C CG    . LEU A 1 812 ? 143.437 144.862 126.589 1.00 55.65  ? 553 LEU A CG    1 
ATOM 1863 C CD1   . LEU A 1 812 ? 143.123 145.729 127.794 1.00 55.07  ? 553 LEU A CD1   1 
ATOM 1864 C CD2   . LEU A 1 812 ? 144.178 143.607 127.020 1.00 51.62  ? 553 LEU A CD2   1 
ATOM 1865 N N     . HIS A 1 813 ? 139.645 144.081 124.030 1.00 55.36  ? 554 HIS A N     1 
ATOM 1866 C CA    . HIS A 1 813 ? 139.199 143.572 122.743 1.00 56.90  ? 554 HIS A CA    1 
ATOM 1867 C C     . HIS A 1 813 ? 137.827 142.928 122.885 1.00 54.98  ? 554 HIS A C     1 
ATOM 1868 O O     . HIS A 1 813 ? 137.281 142.808 123.983 1.00 56.90  ? 554 HIS A O     1 
ATOM 1869 C CB    . HIS A 1 813 ? 140.245 142.612 122.160 1.00 53.34  ? 554 HIS A CB    1 
ATOM 1870 C CG    . HIS A 1 813 ? 140.400 141.334 122.924 1.00 44.58  ? 554 HIS A CG    1 
ATOM 1871 N ND1   . HIS A 1 813 ? 139.477 140.313 122.885 1.00 44.17  ? 554 HIS A ND1   1 
ATOM 1872 C CD2   . HIS A 1 813 ? 141.389 140.914 123.748 1.00 47.45  ? 554 HIS A CD2   1 
ATOM 1873 C CE1   . HIS A 1 813 ? 139.885 139.323 123.659 1.00 48.91  ? 554 HIS A CE1   1 
ATOM 1874 N NE2   . HIS A 1 813 ? 141.044 139.660 124.190 1.00 51.13  ? 554 HIS A NE2   1 
ATOM 1875 N N     . ASP A 1 814 ? 137.268 142.526 121.746 1.00 52.58  ? 555 ASP A N     1 
ATOM 1876 C CA    . ASP A 1 814 ? 135.941 141.935 121.712 1.00 52.68  ? 555 ASP A CA    1 
ATOM 1877 C C     . ASP A 1 814 ? 136.006 140.513 122.270 1.00 51.51  ? 555 ASP A C     1 
ATOM 1878 O O     . ASP A 1 814 ? 137.052 139.858 122.266 1.00 48.99  ? 555 ASP A O     1 
ATOM 1879 C CB    . ASP A 1 814 ? 135.400 141.962 120.273 1.00 57.69  ? 555 ASP A CB    1 
ATOM 1880 C CG    . ASP A 1 814 ? 133.924 141.537 120.151 1.00 63.04  ? 555 ASP A CG    1 
ATOM 1881 O OD1   . ASP A 1 814 ? 133.399 140.747 120.964 1.00 59.44  ? 555 ASP A OD1   1 
ATOM 1882 O OD2   . ASP A 1 814 ? 133.273 142.017 119.199 1.00 70.51  ? 555 ASP A OD2   1 
ATOM 1883 N N     . ARG A 1 815 ? 134.857 140.040 122.759 1.00 51.41  ? 556 ARG A N     1 
ATOM 1884 C CA    . ARG A 1 815 ? 134.806 138.747 123.433 1.00 48.24  ? 556 ARG A CA    1 
ATOM 1885 C C     . ARG A 1 815 ? 134.929 137.589 122.448 1.00 48.29  ? 556 ARG A C     1 
ATOM 1886 O O     . ARG A 1 815 ? 135.673 136.633 122.698 1.00 44.60  ? 556 ARG A O     1 
ATOM 1887 C CB    . ARG A 1 815 ? 133.509 138.637 124.235 1.00 51.48  ? 556 ARG A CB    1 
ATOM 1888 C CG    . ARG A 1 815 ? 133.268 137.274 124.869 1.00 55.74  ? 556 ARG A CG    1 
ATOM 1889 C CD    . ARG A 1 815 ? 131.943 137.239 125.623 1.00 56.76  ? 556 ARG A CD    1 
ATOM 1890 N NE    . ARG A 1 815 ? 131.243 135.972 125.443 1.00 56.72  ? 556 ARG A NE    1 
ATOM 1891 C CZ    . ARG A 1 815 ? 130.130 135.822 124.738 1.00 53.28  ? 556 ARG A CZ    1 
ATOM 1892 N NH1   . ARG A 1 815 ? 129.548 136.847 124.137 1.00 54.69  ? 556 ARG A NH1   1 
ATOM 1893 N NH2   . ARG A 1 815 ? 129.587 134.612 124.632 1.00 49.33  ? 556 ARG A NH2   1 
ATOM 1894 N N     . ASN A 1 816 ? 134.217 137.657 121.318 1.00 50.40  ? 557 ASN A N     1 
ATOM 1895 C CA    . ASN A 1 816 ? 134.132 136.522 120.401 1.00 44.84  ? 557 ASN A CA    1 
ATOM 1896 C C     . ASN A 1 816 ? 135.273 136.558 119.393 1.00 45.72  ? 557 ASN A C     1 
ATOM 1897 O O     . ASN A 1 816 ? 135.493 137.595 118.756 1.00 50.02  ? 557 ASN A O     1 
ATOM 1898 C CB    . ASN A 1 816 ? 132.804 136.521 119.662 1.00 41.61  ? 557 ASN A CB    1 
ATOM 1899 C CG    . ASN A 1 816 ? 131.639 136.202 120.567 1.00 49.55  ? 557 ASN A CG    1 
ATOM 1900 O OD1   . ASN A 1 816 ? 131.497 135.075 121.040 1.00 54.13  ? 557 ASN A OD1   1 
ATOM 1901 N ND2   . ASN A 1 816 ? 130.797 137.194 120.816 1.00 52.71  ? 557 ASN A ND2   1 
ATOM 1902 N N     . PRO A 1 817 ? 136.020 135.465 119.241 1.00 42.82  ? 558 PRO A N     1 
ATOM 1903 C CA    . PRO A 1 817 ? 137.053 135.412 118.204 1.00 41.39  ? 558 PRO A CA    1 
ATOM 1904 C C     . PRO A 1 817 ? 136.455 135.485 116.809 1.00 42.97  ? 558 PRO A C     1 
ATOM 1905 O O     . PRO A 1 817 ? 135.347 135.009 116.557 1.00 49.80  ? 558 PRO A O     1 
ATOM 1906 C CB    . PRO A 1 817 ? 137.729 134.058 118.443 1.00 40.22  ? 558 PRO A CB    1 
ATOM 1907 C CG    . PRO A 1 817 ? 137.430 133.720 119.848 1.00 41.02  ? 558 PRO A CG    1 
ATOM 1908 C CD    . PRO A 1 817 ? 136.086 134.307 120.147 1.00 44.71  ? 558 PRO A CD    1 
ATOM 1909 N N     . LEU A 1 818 ? 137.203 136.096 115.902 1.00 44.32  ? 559 LEU A N     1 
ATOM 1910 C CA    . LEU A 1 818 ? 136.825 136.169 114.500 1.00 47.54  ? 559 LEU A CA    1 
ATOM 1911 C C     . LEU A 1 818 ? 137.680 135.212 113.681 1.00 49.96  ? 559 LEU A C     1 
ATOM 1912 O O     . LEU A 1 818 ? 138.701 134.697 114.140 1.00 51.70  ? 559 LEU A O     1 
ATOM 1913 C CB    . LEU A 1 818 ? 136.966 137.597 113.963 1.00 43.63  ? 559 LEU A CB    1 
ATOM 1914 C CG    . LEU A 1 818 ? 135.832 138.606 114.167 1.00 47.44  ? 559 LEU A CG    1 
ATOM 1915 C CD1   . LEU A 1 818 ? 135.587 138.949 115.627 1.00 45.94  ? 559 LEU A CD1   1 
ATOM 1916 C CD2   . LEU A 1 818 ? 136.114 139.860 113.369 1.00 58.31  ? 559 LEU A CD2   1 
ATOM 1917 N N     . SER A 1 819 ? 137.247 134.977 112.448 1.00 51.43  ? 560 SER A N     1 
ATOM 1918 C CA    . SER A 1 819 ? 137.979 134.148 111.503 1.00 54.65  ? 560 SER A CA    1 
ATOM 1919 C C     . SER A 1 819 ? 138.640 135.049 110.473 1.00 61.35  ? 560 SER A C     1 
ATOM 1920 O O     . SER A 1 819 ? 137.982 135.916 109.887 1.00 65.33  ? 560 SER A O     1 
ATOM 1921 C CB    . SER A 1 819 ? 137.056 133.139 110.818 1.00 57.36  ? 560 SER A CB    1 
ATOM 1922 O OG    . SER A 1 819 ? 137.777 132.327 109.911 1.00 62.68  ? 560 SER A OG    1 
ATOM 1923 N N     . TYR A 1 820 ? 139.936 134.846 110.258 1.00 64.96  ? 561 TYR A N     1 
ATOM 1924 C CA    . TYR A 1 820 ? 140.720 135.691 109.364 1.00 66.49  ? 561 TYR A CA    1 
ATOM 1925 C C     . TYR A 1 820 ? 141.614 134.776 108.542 1.00 68.29  ? 561 TYR A C     1 
ATOM 1926 O O     . TYR A 1 820 ? 142.627 134.282 109.044 1.00 68.80  ? 561 TYR A O     1 
ATOM 1927 C CB    . TYR A 1 820 ? 141.541 136.708 110.158 1.00 66.25  ? 561 TYR A CB    1 
ATOM 1928 C CG    . TYR A 1 820 ? 142.328 137.700 109.329 1.00 67.63  ? 561 TYR A CG    1 
ATOM 1929 C CD1   . TYR A 1 820 ? 143.630 137.426 108.926 1.00 68.48  ? 561 TYR A CD1   1 
ATOM 1930 C CD2   . TYR A 1 820 ? 141.773 138.919 108.964 1.00 71.35  ? 561 TYR A CD2   1 
ATOM 1931 C CE1   . TYR A 1 820 ? 144.351 138.333 108.173 1.00 71.85  ? 561 TYR A CE1   1 
ATOM 1932 C CE2   . TYR A 1 820 ? 142.486 139.832 108.211 1.00 76.65  ? 561 TYR A CE2   1 
ATOM 1933 C CZ    . TYR A 1 820 ? 143.773 139.534 107.819 1.00 75.45  ? 561 TYR A CZ    1 
ATOM 1934 O OH    . TYR A 1 820 ? 144.488 140.439 107.070 1.00 75.71  ? 561 TYR A OH    1 
ATOM 1935 N N     . LYS A 1 821 ? 141.241 134.556 107.284 1.00 72.67  ? 562 LYS A N     1 
ATOM 1936 C CA    . LYS A 1 821 ? 142.006 133.703 106.388 1.00 76.04  ? 562 LYS A CA    1 
ATOM 1937 C C     . LYS A 1 821 ? 142.045 134.354 105.017 1.00 79.78  ? 562 LYS A C     1 
ATOM 1938 O O     . LYS A 1 821 ? 141.040 134.905 104.564 1.00 82.92  ? 562 LYS A O     1 
ATOM 1939 C CB    . LYS A 1 821 ? 141.407 132.296 106.281 1.00 71.64  ? 562 LYS A CB    1 
ATOM 1940 C CG    . LYS A 1 821 ? 141.548 131.446 107.530 1.00 66.61  ? 562 LYS A CG    1 
ATOM 1941 C CD    . LYS A 1 821 ? 140.932 130.075 107.325 1.00 69.76  ? 562 LYS A CD    1 
ATOM 1942 C CE    . LYS A 1 821 ? 141.183 129.180 108.522 1.00 65.61  ? 562 LYS A CE    1 
ATOM 1943 N NZ    . LYS A 1 821 ? 140.596 127.826 108.334 1.00 69.33  ? 562 LYS A NZ    1 
ATOM 1944 N N     . LYS A 1 822 ? 143.216 134.271 104.371 1.00 76.95  ? 563 LYS A N     1 
ATOM 1945 C CA    . LYS A 1 822 ? 143.563 134.815 103.053 1.00 80.52  ? 563 LYS A CA    1 
ATOM 1946 C C     . LYS A 1 822 ? 142.966 136.191 102.762 1.00 81.87  ? 563 LYS A C     1 
ATOM 1947 O O     . LYS A 1 822 ? 142.525 136.460 101.640 1.00 82.87  ? 563 LYS A O     1 
ATOM 1948 C CB    . LYS A 1 822 ? 143.199 133.831 101.923 1.00 82.59  ? 563 LYS A CB    1 
ATOM 1949 C CG    . LYS A 1 822 ? 141.761 133.321 101.836 1.00 82.66  ? 563 LYS A CG    1 
ATOM 1950 C CD    . LYS A 1 822 ? 141.607 132.320 100.704 1.00 87.25  ? 563 LYS A CD    1 
ATOM 1951 C CE    . LYS A 1 822 ? 140.305 132.535 99.952  1.00 87.37  ? 563 LYS A CE    1 
ATOM 1952 N NZ    . LYS A 1 822 ? 139.989 131.392 99.054  1.00 79.90  ? 563 LYS A NZ    1 
ATOM 1953 N N     . GLY A 1 823 ? 142.963 137.073 103.760 1.00 77.60  ? 564 GLY A N     1 
ATOM 1954 C CA    . GLY A 1 823 ? 142.594 138.456 103.563 1.00 78.11  ? 564 GLY A CA    1 
ATOM 1955 C C     . GLY A 1 823 ? 141.122 138.780 103.702 1.00 79.94  ? 564 GLY A C     1 
ATOM 1956 O O     . GLY A 1 823 ? 140.770 139.966 103.713 1.00 81.57  ? 564 GLY A O     1 
ATOM 1957 N N     . ILE A 1 824 ? 140.249 137.782 103.810 1.00 80.21  ? 565 ILE A N     1 
ATOM 1958 C CA    . ILE A 1 824 ? 138.820 138.012 103.994 1.00 79.93  ? 565 ILE A CA    1 
ATOM 1959 C C     . ILE A 1 824 ? 138.468 137.699 105.443 1.00 78.19  ? 565 ILE A C     1 
ATOM 1960 O O     . ILE A 1 824 ? 138.890 136.672 105.989 1.00 78.11  ? 565 ILE A O     1 
ATOM 1961 C CB    . ILE A 1 824 ? 137.969 137.198 102.997 1.00 82.00  ? 565 ILE A CB    1 
ATOM 1962 C CG1   . ILE A 1 824 ? 136.474 137.402 103.258 1.00 83.46  ? 565 ILE A CG1   1 
ATOM 1963 C CG2   . ILE A 1 824 ? 138.338 135.719 102.991 1.00 80.13  ? 565 ILE A CG2   1 
ATOM 1964 C CD1   . ILE A 1 824 ? 135.999 138.811 103.005 1.00 83.39  ? 565 ILE A CD1   1 
ATOM 1965 N N     . ILE A 1 825 ? 137.734 138.609 106.075 1.00 79.75  ? 566 ILE A N     1 
ATOM 1966 C CA    . ILE A 1 825 ? 137.383 138.521 107.487 1.00 78.82  ? 566 ILE A CA    1 
ATOM 1967 C C     . ILE A 1 825 ? 135.911 138.140 107.581 1.00 79.90  ? 566 ILE A C     1 
ATOM 1968 O O     . ILE A 1 825 ? 135.043 138.840 107.043 1.00 86.18  ? 566 ILE A O     1 
ATOM 1969 C CB    . ILE A 1 825 ? 137.676 139.842 108.215 1.00 72.94  ? 566 ILE A CB    1 
ATOM 1970 C CG1   . ILE A 1 825 ? 136.857 140.991 107.621 1.00 70.06  ? 566 ILE A CG1   1 
ATOM 1971 C CG2   . ILE A 1 825 ? 139.178 140.130 108.210 1.00 73.09  ? 566 ILE A CG2   1 
ATOM 1972 C CD1   . ILE A 1 825 ? 136.932 142.267 108.421 1.00 74.93  ? 566 ILE A CD1   1 
ATOM 1973 N N     . THR A 1 826 ? 135.632 137.014 108.236 1.00 72.22  ? 567 THR A N     1 
ATOM 1974 C CA    . THR A 1 826 ? 134.278 136.495 108.365 1.00 71.67  ? 567 THR A CA    1 
ATOM 1975 C C     . THR A 1 826 ? 134.061 135.985 109.781 1.00 68.98  ? 567 THR A C     1 
ATOM 1976 O O     . THR A 1 826 ? 135.008 135.639 110.490 1.00 68.10  ? 567 THR A O     1 
ATOM 1977 C CB    . THR A 1 826 ? 133.990 135.351 107.376 1.00 70.75  ? 567 THR A CB    1 
ATOM 1978 O OG1   . THR A 1 826 ? 134.955 134.307 107.552 1.00 69.64  ? 567 THR A OG1   1 
ATOM 1979 C CG2   . THR A 1 826 ? 134.005 135.830 105.929 1.00 74.22  ? 567 THR A CG2   1 
ATOM 1980 N N     . ARG A 1 827 ? 132.794 135.944 110.191 1.00 68.25  ? 568 ARG A N     1 
ATOM 1981 C CA    . ARG A 1 827 ? 132.404 135.283 111.427 1.00 61.03  ? 568 ARG A CA    1 
ATOM 1982 C C     . ARG A 1 827 ? 131.094 134.548 111.192 1.00 64.27  ? 568 ARG A C     1 
ATOM 1983 O O     . ARG A 1 827 ? 130.201 135.060 110.513 1.00 74.38  ? 568 ARG A O     1 
ATOM 1984 C CB    . ARG A 1 827 ? 132.242 136.268 112.593 1.00 61.05  ? 568 ARG A CB    1 
ATOM 1985 C CG    . ARG A 1 827 ? 132.016 135.569 113.927 1.00 57.43  ? 568 ARG A CG    1 
ATOM 1986 C CD    . ARG A 1 827 ? 131.749 136.520 115.071 1.00 54.92  ? 568 ARG A CD    1 
ATOM 1987 N NE    . ARG A 1 827 ? 131.195 135.805 116.214 1.00 52.88  ? 568 ARG A NE    1 
ATOM 1988 C CZ    . ARG A 1 827 ? 129.925 135.849 116.590 1.00 55.82  ? 568 ARG A CZ    1 
ATOM 1989 N NH1   . ARG A 1 827 ? 129.038 136.582 115.944 1.00 59.88  ? 568 ARG A NH1   1 
ATOM 1990 N NH2   . ARG A 1 827 ? 129.537 135.140 117.646 1.00 54.26  ? 568 ARG A NH2   1 
ATOM 1991 N N     . ARG A 1 828 ? 130.988 133.346 111.750 1.00 58.93  ? 569 ARG A N     1 
ATOM 1992 C CA    . ARG A 1 828 ? 129.798 132.525 111.583 1.00 60.44  ? 569 ARG A CA    1 
ATOM 1993 C C     . ARG A 1 828 ? 128.692 132.997 112.522 1.00 62.25  ? 569 ARG A C     1 
ATOM 1994 O O     . ARG A 1 828 ? 128.926 133.207 113.715 1.00 62.56  ? 569 ARG A O     1 
ATOM 1995 C CB    . ARG A 1 828 ? 130.148 131.064 111.849 1.00 55.04  ? 569 ARG A CB    1 
ATOM 1996 C CG    . ARG A 1 828 ? 129.039 130.076 111.610 1.00 65.34  ? 569 ARG A CG    1 
ATOM 1997 C CD    . ARG A 1 828 ? 129.439 128.723 112.162 1.00 68.40  ? 569 ARG A CD    1 
ATOM 1998 N NE    . ARG A 1 828 ? 130.339 128.001 111.273 1.00 76.09  ? 569 ARG A NE    1 
ATOM 1999 C CZ    . ARG A 1 828 ? 130.069 126.820 110.737 1.00 83.06  ? 569 ARG A CZ    1 
ATOM 2000 N NH1   . ARG A 1 828 ? 128.931 126.194 110.983 1.00 84.78  ? 569 ARG A NH1   1 
ATOM 2001 N NH2   . ARG A 1 828 ? 130.966 126.250 109.937 1.00 84.86  ? 569 ARG A NH2   1 
ATOM 2002 N N     . PHE A 1 829 ? 127.488 133.166 111.980 1.00 72.79  ? 570 PHE A N     1 
ATOM 2003 C CA    . PHE A 1 829 ? 126.319 133.590 112.739 1.00 76.63  ? 570 PHE A CA    1 
ATOM 2004 C C     . PHE A 1 829 ? 125.199 132.568 112.613 1.00 83.30  ? 570 PHE A C     1 
ATOM 2005 O O     . PHE A 1 829 ? 125.061 131.894 111.589 1.00 86.07  ? 570 PHE A O     1 
ATOM 2006 C CB    . PHE A 1 829 ? 125.775 134.945 112.263 1.00 80.24  ? 570 PHE A CB    1 
ATOM 2007 C CG    . PHE A 1 829 ? 126.581 136.134 112.698 1.00 75.42  ? 570 PHE A CG    1 
ATOM 2008 C CD1   . PHE A 1 829 ? 127.802 136.419 112.118 1.00 71.51  ? 570 PHE A CD1   1 
ATOM 2009 C CD2   . PHE A 1 829 ? 126.084 136.998 113.661 1.00 75.18  ? 570 PHE A CD2   1 
ATOM 2010 C CE1   . PHE A 1 829 ? 128.529 137.527 112.509 1.00 67.70  ? 570 PHE A CE1   1 
ATOM 2011 C CE2   . PHE A 1 829 ? 126.803 138.108 114.055 1.00 69.12  ? 570 PHE A CE2   1 
ATOM 2012 C CZ    . PHE A 1 829 ? 128.026 138.374 113.476 1.00 68.18  ? 570 PHE A CZ    1 
ATOM 2013 N N     . MET A 1 830 ? 124.391 132.471 113.663 1.00 85.38  ? 571 MET A N     1 
ATOM 2014 C CA    . MET A 1 830 ? 123.135 131.747 113.573 1.00 89.67  ? 571 MET A CA    1 
ATOM 2015 C C     . MET A 1 830 ? 122.142 132.541 112.729 1.00 94.89  ? 571 MET A C     1 
ATOM 2016 O O     . MET A 1 830 ? 122.255 133.760 112.581 1.00 100.47 ? 571 MET A O     1 
ATOM 2017 C CB    . MET A 1 830 ? 122.564 131.493 114.966 1.00 94.37  ? 571 MET A CB    1 
ATOM 2018 C CG    . MET A 1 830 ? 123.255 130.370 115.724 1.00 92.46  ? 571 MET A CG    1 
ATOM 2019 S SD    . MET A 1 830 ? 122.506 129.953 117.316 1.00 96.01  ? 571 MET A SD    1 
ATOM 2020 C CE    . MET A 1 830 ? 121.178 131.151 117.443 1.00 100.11 ? 571 MET A CE    1 
ATOM 2021 N N     . VAL A 1 831 ? 121.158 131.829 112.172 1.00 92.91  ? 572 VAL A N     1 
ATOM 2022 C CA    . VAL A 1 831 ? 120.183 132.454 111.278 1.00 96.41  ? 572 VAL A CA    1 
ATOM 2023 C C     . VAL A 1 831 ? 119.321 133.460 112.035 1.00 99.87  ? 572 VAL A C     1 
ATOM 2024 O O     . VAL A 1 831 ? 119.015 134.545 111.523 1.00 100.76 ? 572 VAL A O     1 
ATOM 2025 C CB    . VAL A 1 831 ? 119.344 131.364 110.582 1.00 93.45  ? 572 VAL A CB    1 
ATOM 2026 C CG1   . VAL A 1 831 ? 117.951 131.859 110.219 1.00 98.55  ? 572 VAL A CG1   1 
ATOM 2027 C CG2   . VAL A 1 831 ? 120.059 130.888 109.335 1.00 95.36  ? 572 VAL A CG2   1 
ATOM 2028 N N     . THR A 1 832 ? 118.948 133.130 113.273 1.00 101.20 ? 573 THR A N     1 
ATOM 2029 C CA    . THR A 1 832 ? 118.186 134.056 114.105 1.00 107.74 ? 573 THR A CA    1 
ATOM 2030 C C     . THR A 1 832 ? 118.985 135.321 114.402 1.00 108.96 ? 573 THR A C     1 
ATOM 2031 O O     . THR A 1 832 ? 118.436 136.430 114.399 1.00 113.24 ? 573 THR A O     1 
ATOM 2032 C CB    . THR A 1 832 ? 117.779 133.358 115.405 1.00 113.05 ? 573 THR A CB    1 
ATOM 2033 O OG1   . THR A 1 832 ? 117.003 132.194 115.098 1.00 112.30 ? 573 THR A OG1   1 
ATOM 2034 C CG2   . THR A 1 832 ? 116.959 134.285 116.293 1.00 120.33 ? 573 THR A CG2   1 
ATOM 2035 N N     . GLU A 1 833 ? 120.293 135.177 114.625 1.00 105.50 ? 574 GLU A N     1 
ATOM 2036 C CA    . GLU A 1 833 ? 121.122 136.315 115.002 1.00 105.77 ? 574 GLU A CA    1 
ATOM 2037 C C     . GLU A 1 833 ? 121.366 137.282 113.850 1.00 106.06 ? 574 GLU A C     1 
ATOM 2038 O O     . GLU A 1 833 ? 121.707 138.443 114.102 1.00 107.91 ? 574 GLU A O     1 
ATOM 2039 C CB    . GLU A 1 833 ? 122.456 135.818 115.562 1.00 101.63 ? 574 GLU A CB    1 
ATOM 2040 C CG    . GLU A 1 833 ? 122.319 134.994 116.834 1.00 103.94 ? 574 GLU A CG    1 
ATOM 2041 C CD    . GLU A 1 833 ? 123.640 134.425 117.314 1.00 104.24 ? 574 GLU A CD    1 
ATOM 2042 O OE1   . GLU A 1 833 ? 124.374 133.845 116.488 1.00 98.52  ? 574 GLU A OE1   1 
ATOM 2043 O OE2   . GLU A 1 833 ? 123.940 134.552 118.519 1.00 111.44 ? 574 GLU A OE2   1 
ATOM 2044 N N     . ILE A 1 834 ? 121.203 136.844 112.601 1.00 106.63 ? 575 ILE A N     1 
ATOM 2045 C CA    . ILE A 1 834 ? 121.431 137.725 111.459 1.00 109.31 ? 575 ILE A CA    1 
ATOM 2046 C C     . ILE A 1 834 ? 120.298 138.739 111.372 1.00 113.65 ? 575 ILE A C     1 
ATOM 2047 O O     . ILE A 1 834 ? 119.118 138.373 111.320 1.00 115.87 ? 575 ILE A O     1 
ATOM 2048 C CB    . ILE A 1 834 ? 121.556 136.925 110.155 1.00 105.86 ? 575 ILE A CB    1 
ATOM 2049 C CG1   . ILE A 1 834 ? 122.713 135.932 110.237 1.00 100.23 ? 575 ILE A CG1   1 
ATOM 2050 C CG2   . ILE A 1 834 ? 121.758 137.859 108.977 1.00 107.79 ? 575 ILE A CG2   1 
ATOM 2051 C CD1   . ILE A 1 834 ? 122.782 134.983 109.063 1.00 96.47  ? 575 ILE A CD1   1 
ATOM 2052 N N     . GLU A 1 835 ? 120.655 140.018 111.359 1.00 117.65 ? 576 GLU A N     1 
ATOM 2053 C CA    . GLU A 1 835 ? 119.673 141.086 111.276 1.00 126.64 ? 576 GLU A CA    1 
ATOM 2054 C C     . GLU A 1 835 ? 119.183 141.224 109.835 1.00 131.49 ? 576 GLU A C     1 
ATOM 2055 O O     . GLU A 1 835 ? 119.911 140.930 108.882 1.00 128.98 ? 576 GLU A O     1 
ATOM 2056 C CB    . GLU A 1 835 ? 120.293 142.389 111.791 1.00 131.89 ? 576 GLU A CB    1 
ATOM 2057 C CG    . GLU A 1 835 ? 119.376 143.600 111.858 1.00 137.84 ? 576 GLU A CG    1 
ATOM 2058 C CD    . GLU A 1 835 ? 119.913 144.672 112.786 1.00 138.48 ? 576 GLU A CD    1 
ATOM 2059 O OE1   . GLU A 1 835 ? 121.130 144.657 113.067 1.00 136.36 ? 576 GLU A OE1   1 
ATOM 2060 O OE2   . GLU A 1 835 ? 119.121 145.521 113.243 1.00 139.35 ? 576 GLU A OE2   1 
ATOM 2061 N N     . CYS A 1 836 ? 117.929 141.668 109.686 1.00 138.12 ? 577 CYS A N     1 
ATOM 2062 C CA    . CYS A 1 836 ? 117.284 141.753 108.377 1.00 137.95 ? 577 CYS A CA    1 
ATOM 2063 C C     . CYS A 1 836 ? 117.941 142.784 107.462 1.00 136.66 ? 577 CYS A C     1 
ATOM 2064 O O     . CYS A 1 836 ? 117.813 142.683 106.238 1.00 133.96 ? 577 CYS A O     1 
ATOM 2065 C CB    . CYS A 1 836 ? 115.794 142.065 108.568 1.00 139.47 ? 577 CYS A CB    1 
ATOM 2066 S SG    . CYS A 1 836 ? 114.809 142.404 107.085 1.00 140.93 ? 577 CYS A SG    1 
ATOM 2067 N N     . GLY A 1 837 ? 118.652 143.762 108.018 1.00 137.08 ? 578 GLY A N     1 
ATOM 2068 C CA    . GLY A 1 837 ? 119.371 144.707 107.183 1.00 136.14 ? 578 GLY A CA    1 
ATOM 2069 C C     . GLY A 1 837 ? 120.720 144.237 106.680 1.00 133.22 ? 578 GLY A C     1 
ATOM 2070 O O     . GLY A 1 837 ? 121.363 144.962 105.915 1.00 132.19 ? 578 GLY A O     1 
ATOM 2071 N N     . LYS A 1 838 ? 121.167 143.046 107.087 1.00 130.78 ? 579 LYS A N     1 
ATOM 2072 C CA    . LYS A 1 838 ? 122.522 142.584 106.803 1.00 127.73 ? 579 LYS A CA    1 
ATOM 2073 C C     . LYS A 1 838 ? 122.550 141.278 106.015 1.00 126.09 ? 579 LYS A C     1 
ATOM 2074 O O     . LYS A 1 838 ? 123.544 140.549 106.076 1.00 122.16 ? 579 LYS A O     1 
ATOM 2075 C CB    . LYS A 1 838 ? 123.306 142.423 108.108 1.00 126.13 ? 579 LYS A CB    1 
ATOM 2076 C CG    . LYS A 1 838 ? 123.343 143.672 108.973 1.00 127.59 ? 579 LYS A CG    1 
ATOM 2077 C CD    . LYS A 1 838 ? 124.333 143.530 110.120 1.00 125.17 ? 579 LYS A CD    1 
ATOM 2078 C CE    . LYS A 1 838 ? 125.768 143.539 109.622 1.00 126.76 ? 579 LYS A CE    1 
ATOM 2079 N NZ    . LYS A 1 838 ? 126.745 143.449 110.742 1.00 127.48 ? 579 LYS A NZ    1 
ATOM 2080 N N     . GLU A 1 839 ? 121.482 140.960 105.277 1.00 127.85 ? 580 GLU A N     1 
ATOM 2081 C CA    . GLU A 1 839 ? 121.428 139.692 104.554 1.00 126.31 ? 580 GLU A CA    1 
ATOM 2082 C C     . GLU A 1 839 ? 122.405 139.626 103.388 1.00 122.34 ? 580 GLU A C     1 
ATOM 2083 O O     . GLU A 1 839 ? 122.779 138.523 102.976 1.00 119.18 ? 580 GLU A O     1 
ATOM 2084 C CB    . GLU A 1 839 ? 120.009 139.423 104.049 1.00 126.97 ? 580 GLU A CB    1 
ATOM 2085 C CG    . GLU A 1 839 ? 118.924 139.986 104.937 1.00 128.33 ? 580 GLU A CG    1 
ATOM 2086 C CD    . GLU A 1 839 ? 117.531 139.600 104.482 1.00 129.08 ? 580 GLU A CD    1 
ATOM 2087 O OE1   . GLU A 1 839 ? 117.406 138.934 103.432 1.00 127.51 ? 580 GLU A OE1   1 
ATOM 2088 O OE2   . GLU A 1 839 ? 116.559 139.960 105.178 1.00 130.19 ? 580 GLU A OE2   1 
ATOM 2089 N N     . ASP A 1 840 ? 122.829 140.769 102.848 1.00 125.69 ? 581 ASP A N     1 
ATOM 2090 C CA    . ASP A 1 840 ? 123.779 140.766 101.741 1.00 125.33 ? 581 ASP A CA    1 
ATOM 2091 C C     . ASP A 1 840 ? 125.193 140.409 102.176 1.00 119.46 ? 581 ASP A C     1 
ATOM 2092 O O     . ASP A 1 840 ? 126.037 140.140 101.314 1.00 117.84 ? 581 ASP A O     1 
ATOM 2093 C CB    . ASP A 1 840 ? 123.785 142.129 101.045 1.00 128.67 ? 581 ASP A CB    1 
ATOM 2094 C CG    . ASP A 1 840 ? 123.589 143.280 102.013 1.00 132.36 ? 581 ASP A CG    1 
ATOM 2095 O OD1   . ASP A 1 840 ? 123.445 143.025 103.227 1.00 130.75 ? 581 ASP A OD1   1 
ATOM 2096 O OD2   . ASP A 1 840 ? 123.580 144.443 101.559 1.00 136.91 ? 581 ASP A OD2   1 
ATOM 2097 N N     . ASP A 1 841 ? 125.471 140.396 103.478 1.00 114.53 ? 582 ASP A N     1 
ATOM 2098 C CA    . ASP A 1 841 ? 126.809 140.119 103.980 1.00 107.42 ? 582 ASP A CA    1 
ATOM 2099 C C     . ASP A 1 841 ? 127.132 138.632 104.042 1.00 99.41  ? 582 ASP A C     1 
ATOM 2100 O O     . ASP A 1 841 ? 128.286 138.279 104.303 1.00 93.41  ? 582 ASP A O     1 
ATOM 2101 C CB    . ASP A 1 841 ? 126.980 140.739 105.368 1.00 107.60 ? 582 ASP A CB    1 
ATOM 2102 C CG    . ASP A 1 841 ? 126.873 142.252 105.348 1.00 112.26 ? 582 ASP A CG    1 
ATOM 2103 O OD1   . ASP A 1 841 ? 127.242 142.863 104.324 1.00 111.31 ? 582 ASP A OD1   1 
ATOM 2104 O OD2   . ASP A 1 841 ? 126.418 142.830 106.357 1.00 113.82 ? 582 ASP A OD2   1 
ATOM 2105 N N     . VAL A 1 842 ? 126.152 137.757 103.816 1.00 100.75 ? 583 VAL A N     1 
ATOM 2106 C CA    . VAL A 1 842 ? 126.388 136.321 103.901 1.00 98.81  ? 583 VAL A CA    1 
ATOM 2107 C C     . VAL A 1 842 ? 127.219 135.871 102.707 1.00 104.03 ? 583 VAL A C     1 
ATOM 2108 O O     . VAL A 1 842 ? 126.875 136.148 101.551 1.00 110.80 ? 583 VAL A O     1 
ATOM 2109 C CB    . VAL A 1 842 ? 125.053 135.567 103.971 1.00 101.43 ? 583 VAL A CB    1 
ATOM 2110 C CG1   . VAL A 1 842 ? 125.280 134.070 103.896 1.00 104.39 ? 583 VAL A CG1   1 
ATOM 2111 C CG2   . VAL A 1 842 ? 124.305 135.938 105.237 1.00 98.02  ? 583 VAL A CG2   1 
ATOM 2112 N N     . ILE A 1 843 ? 128.328 135.179 102.983 1.00 99.46  ? 584 ILE A N     1 
ATOM 2113 C CA    . ILE A 1 843 ? 129.219 134.739 101.913 1.00 103.24 ? 584 ILE A CA    1 
ATOM 2114 C C     . ILE A 1 843 ? 128.574 133.621 101.100 1.00 107.06 ? 584 ILE A C     1 
ATOM 2115 O O     . ILE A 1 843 ? 128.681 133.590 99.868  1.00 109.21 ? 584 ILE A O     1 
ATOM 2116 C CB    . ILE A 1 843 ? 130.584 134.326 102.500 1.00 102.51 ? 584 ILE A CB    1 
ATOM 2117 C CG1   . ILE A 1 843 ? 131.407 133.511 101.499 1.00 107.72 ? 584 ILE A CG1   1 
ATOM 2118 C CG2   . ILE A 1 843 ? 130.401 133.556 103.789 1.00 95.92  ? 584 ILE A CG2   1 
ATOM 2119 C CD1   . ILE A 1 843 ? 132.802 133.180 101.983 1.00 104.87 ? 584 ILE A CD1   1 
ATOM 2120 N N     . SER A 1 844 ? 127.873 132.705 101.766 1.00 106.50 ? 585 SER A N     1 
ATOM 2121 C CA    . SER A 1 844 ? 127.190 131.621 101.070 1.00 111.19 ? 585 SER A CA    1 
ATOM 2122 C C     . SER A 1 844 ? 126.015 132.181 100.279 1.00 115.44 ? 585 SER A C     1 
ATOM 2123 O O     . SER A 1 844 ? 125.064 132.714 100.859 1.00 115.62 ? 585 SER A O     1 
ATOM 2124 C CB    . SER A 1 844 ? 126.715 130.566 102.065 1.00 108.08 ? 585 SER A CB    1 
ATOM 2125 O OG    . SER A 1 844 ? 126.260 129.406 101.391 1.00 108.46 ? 585 SER A OG    1 
ATOM 2126 N N     . GLU A 1 845 ? 126.089 132.067 98.951  1.00 117.21 ? 586 GLU A N     1 
ATOM 2127 C CA    . GLU A 1 845 ? 125.110 132.729 98.095  1.00 117.53 ? 586 GLU A CA    1 
ATOM 2128 C C     . GLU A 1 845 ? 123.745 132.058 98.177  1.00 119.74 ? 586 GLU A C     1 
ATOM 2129 O O     . GLU A 1 845 ? 122.726 132.741 98.311  1.00 120.21 ? 586 GLU A O     1 
ATOM 2130 C CB    . GLU A 1 845 ? 125.611 132.762 96.648  1.00 114.63 ? 586 GLU A CB    1 
ATOM 2131 C CG    . GLU A 1 845 ? 126.962 133.466 96.415  1.00 117.50 ? 586 GLU A CG    1 
ATOM 2132 C CD    . GLU A 1 845 ? 126.952 134.991 96.590  1.00 118.75 ? 586 GLU A CD    1 
ATOM 2133 O OE1   . GLU A 1 845 ? 125.965 135.579 97.084  1.00 116.08 ? 586 GLU A OE1   1 
ATOM 2134 O OE2   . GLU A 1 845 ? 127.967 135.616 96.218  1.00 121.13 ? 586 GLU A OE2   1 
ATOM 2135 N N     . THR A 1 846 ? 123.707 130.722 98.109  1.00 120.19 ? 587 THR A N     1 
ATOM 2136 C CA    . THR A 1 846 ? 122.433 130.005 98.048  1.00 118.98 ? 587 THR A CA    1 
ATOM 2137 C C     . THR A 1 846 ? 121.623 130.188 99.326  1.00 116.81 ? 587 THR A C     1 
ATOM 2138 O O     . THR A 1 846 ? 120.403 130.395 99.277  1.00 116.25 ? 587 THR A O     1 
ATOM 2139 C CB    . THR A 1 846 ? 122.679 128.521 97.784  1.00 116.28 ? 587 THR A CB    1 
ATOM 2140 O OG1   . THR A 1 846 ? 123.596 128.006 98.757  1.00 112.68 ? 587 THR A OG1   1 
ATOM 2141 C CG2   . THR A 1 846 ? 123.259 128.319 96.394  1.00 114.62 ? 587 THR A CG2   1 
ATOM 2142 N N     . TYR A 1 847 ? 122.287 130.138 100.481 1.00 115.12 ? 588 TYR A N     1 
ATOM 2143 C CA    . TYR A 1 847 ? 121.592 130.413 101.731 1.00 114.52 ? 588 TYR A CA    1 
ATOM 2144 C C     . TYR A 1 847 ? 121.196 131.880 101.841 1.00 115.96 ? 588 TYR A C     1 
ATOM 2145 O O     . TYR A 1 847 ? 120.214 132.202 102.515 1.00 116.83 ? 588 TYR A O     1 
ATOM 2146 C CB    . TYR A 1 847 ? 122.457 129.988 102.914 1.00 110.43 ? 588 TYR A CB    1 
ATOM 2147 C CG    . TYR A 1 847 ? 122.583 128.487 103.051 1.00 108.93 ? 588 TYR A CG    1 
ATOM 2148 C CD1   . TYR A 1 847 ? 121.544 127.732 103.581 1.00 107.06 ? 588 TYR A CD1   1 
ATOM 2149 C CD2   . TYR A 1 847 ? 123.735 127.824 102.647 1.00 105.22 ? 588 TYR A CD2   1 
ATOM 2150 C CE1   . TYR A 1 847 ? 121.649 126.361 103.707 1.00 105.26 ? 588 TYR A CE1   1 
ATOM 2151 C CE2   . TYR A 1 847 ? 123.849 126.452 102.770 1.00 102.27 ? 588 TYR A CE2   1 
ATOM 2152 C CZ    . TYR A 1 847 ? 122.803 125.726 103.301 1.00 103.31 ? 588 TYR A CZ    1 
ATOM 2153 O OH    . TYR A 1 847 ? 122.908 124.361 103.426 1.00 102.42 ? 588 TYR A OH    1 
ATOM 2154 N N     . ARG A 1 848 ? 121.920 132.776 101.164 1.00 115.97 ? 589 ARG A N     1 
ATOM 2155 C CA    . ARG A 1 848 ? 121.498 134.173 101.110 1.00 117.80 ? 589 ARG A CA    1 
ATOM 2156 C C     . ARG A 1 848 ? 120.205 134.333 100.313 1.00 120.80 ? 589 ARG A C     1 
ATOM 2157 O O     . ARG A 1 848 ? 119.303 135.069 100.733 1.00 120.83 ? 589 ARG A O     1 
ATOM 2158 C CB    . ARG A 1 848 ? 122.617 135.037 100.526 1.00 118.38 ? 589 ARG A CB    1 
ATOM 2159 C CG    . ARG A 1 848 ? 122.263 136.498 100.323 1.00 119.93 ? 589 ARG A CG    1 
ATOM 2160 C CD    . ARG A 1 848 ? 123.504 137.301 99.968  1.00 119.13 ? 589 ARG A CD    1 
ATOM 2161 N NE    . ARG A 1 848 ? 123.179 138.506 99.217  1.00 124.43 ? 589 ARG A NE    1 
ATOM 2162 C CZ    . ARG A 1 848 ? 123.038 138.548 97.900  1.00 126.56 ? 589 ARG A CZ    1 
ATOM 2163 N NH1   . ARG A 1 848 ? 123.190 137.467 97.154  1.00 122.82 ? 589 ARG A NH1   1 
ATOM 2164 N NH2   . ARG A 1 848 ? 122.736 139.705 97.316  1.00 128.53 ? 589 ARG A NH2   1 
ATOM 2165 N N     . GLU A 1 849 ? 120.085 133.640 99.172  1.00 122.03 ? 590 GLU A N     1 
ATOM 2166 C CA    . GLU A 1 849 ? 118.817 133.651 98.442  1.00 124.22 ? 590 GLU A CA    1 
ATOM 2167 C C     . GLU A 1 849 ? 117.699 133.022 99.261  1.00 124.20 ? 590 GLU A C     1 
ATOM 2168 O O     . GLU A 1 849 ? 116.562 133.506 99.241  1.00 128.65 ? 590 GLU A O     1 
ATOM 2169 C CB    . GLU A 1 849 ? 118.926 132.933 97.092  1.00 125.69 ? 590 GLU A CB    1 
ATOM 2170 C CG    . GLU A 1 849 ? 120.275 132.956 96.422  1.00 127.65 ? 590 GLU A CG    1 
ATOM 2171 C CD    . GLU A 1 849 ? 120.323 132.108 95.166  1.00 129.87 ? 590 GLU A CD    1 
ATOM 2172 O OE1   . GLU A 1 849 ? 119.512 131.166 95.053  1.00 130.23 ? 590 GLU A OE1   1 
ATOM 2173 O OE2   . GLU A 1 849 ? 121.176 132.379 94.297  1.00 130.93 ? 590 GLU A OE2   1 
ATOM 2174 N N     . LYS A 1 850 ? 117.996 131.932 99.974  1.00 120.14 ? 591 LYS A N     1 
ATOM 2175 C CA    . LYS A 1 850 ? 116.957 131.305 100.785 1.00 119.64 ? 591 LYS A CA    1 
ATOM 2176 C C     . LYS A 1 850 ? 116.526 132.202 101.940 1.00 122.06 ? 591 LYS A C     1 
ATOM 2177 O O     . LYS A 1 850 ? 115.342 132.232 102.284 1.00 125.34 ? 591 LYS A O     1 
ATOM 2178 C CB    . LYS A 1 850 ? 117.423 129.943 101.295 1.00 116.86 ? 591 LYS A CB    1 
ATOM 2179 C CG    . LYS A 1 850 ? 116.290 129.092 101.858 1.00 115.44 ? 591 LYS A CG    1 
ATOM 2180 C CD    . LYS A 1 850 ? 116.431 127.616 101.500 1.00 117.34 ? 591 LYS A CD    1 
ATOM 2181 C CE    . LYS A 1 850 ? 117.865 127.122 101.603 1.00 119.48 ? 591 LYS A CE    1 
ATOM 2182 N NZ    . LYS A 1 850 ? 118.029 125.791 100.958 1.00 118.80 ? 591 LYS A NZ    1 
ATOM 2183 N N     . LEU A 1 851 ? 117.451 132.975 102.513 1.00 122.54 ? 592 LEU A N     1 
ATOM 2184 C CA    . LEU A 1 851 ? 117.074 133.955 103.527 1.00 123.71 ? 592 LEU A CA    1 
ATOM 2185 C C     . LEU A 1 851 ? 116.255 135.088 102.916 1.00 125.81 ? 592 LEU A C     1 
ATOM 2186 O O     . LEU A 1 851 ? 115.336 135.614 103.558 1.00 127.75 ? 592 LEU A O     1 
ATOM 2187 C CB    . LEU A 1 851 ? 118.327 134.500 104.213 1.00 119.69 ? 592 LEU A CB    1 
ATOM 2188 C CG    . LEU A 1 851 ? 118.177 135.504 105.359 1.00 116.40 ? 592 LEU A CG    1 
ATOM 2189 C CD1   . LEU A 1 851 ? 117.079 135.089 106.329 1.00 115.77 ? 592 LEU A CD1   1 
ATOM 2190 C CD2   . LEU A 1 851 ? 119.498 135.676 106.088 1.00 116.48 ? 592 LEU A CD2   1 
ATOM 2191 N N     . LYS A 1 852 ? 116.569 135.470 101.674 1.00 124.29 ? 593 LYS A N     1 
ATOM 2192 C CA    . LYS A 1 852 ? 115.801 136.511 100.993 1.00 127.93 ? 593 LYS A CA    1 
ATOM 2193 C C     . LYS A 1 852 ? 114.358 136.073 100.758 1.00 133.26 ? 593 LYS A C     1 
ATOM 2194 O O     . LYS A 1 852 ? 113.413 136.809 101.070 1.00 137.04 ? 593 LYS A O     1 
ATOM 2195 C CB    . LYS A 1 852 ? 116.477 136.876 99.672  1.00 127.48 ? 593 LYS A CB    1 
ATOM 2196 N N     . GLU A 1 853 ? 114.163 134.865 100.225 1.00 132.88 ? 594 GLU A N     1 
ATOM 2197 C CA    . GLU A 1 853 ? 112.797 134.368 100.061 1.00 134.84 ? 594 GLU A CA    1 
ATOM 2198 C C     . GLU A 1 853 ? 112.158 133.957 101.383 1.00 138.12 ? 594 GLU A C     1 
ATOM 2199 O O     . GLU A 1 853 ? 110.935 133.815 101.437 1.00 141.62 ? 594 GLU A O     1 
ATOM 2200 C CB    . GLU A 1 853 ? 112.708 133.201 99.063  1.00 133.15 ? 594 GLU A CB    1 
ATOM 2201 C CG    . GLU A 1 853 ? 113.719 133.135 97.913  1.00 133.99 ? 594 GLU A CG    1 
ATOM 2202 C CD    . GLU A 1 853 ? 113.950 134.471 97.219  1.00 134.50 ? 594 GLU A CD    1 
ATOM 2203 O OE1   . GLU A 1 853 ? 112.990 135.007 96.625  1.00 136.58 ? 594 GLU A OE1   1 
ATOM 2204 O OE2   . GLU A 1 853 ? 115.085 134.986 97.270  1.00 130.89 ? 594 GLU A OE2   1 
ATOM 2205 N N     . ALA A 1 854 ? 112.942 133.769 102.446 1.00 137.68 ? 595 ALA A N     1 
ATOM 2206 C CA    . ALA A 1 854 ? 112.346 133.598 103.766 1.00 137.18 ? 595 ALA A CA    1 
ATOM 2207 C C     . ALA A 1 854 ? 111.780 134.914 104.281 1.00 137.22 ? 595 ALA A C     1 
ATOM 2208 O O     . ALA A 1 854 ? 110.710 134.939 104.900 1.00 140.19 ? 595 ALA A O     1 
ATOM 2209 C CB    . ALA A 1 854 ? 113.378 133.033 104.741 1.00 132.26 ? 595 ALA A CB    1 
ATOM 2210 N N     . PHE A 1 855 ? 112.492 136.017 104.038 1.00 135.40 ? 596 PHE A N     1 
ATOM 2211 C CA    . PHE A 1 855 ? 111.959 137.332 104.376 1.00 138.70 ? 596 PHE A CA    1 
ATOM 2212 C C     . PHE A 1 855 ? 110.794 137.714 103.470 1.00 143.73 ? 596 PHE A C     1 
ATOM 2213 O O     . PHE A 1 855 ? 109.915 138.477 103.882 1.00 145.37 ? 596 PHE A O     1 
ATOM 2214 C CB    . PHE A 1 855 ? 113.064 138.385 104.291 1.00 134.86 ? 596 PHE A CB    1 
ATOM 2215 N N     . LYS A 1 856 ? 110.780 137.210 102.237 1.00 144.75 ? 597 LYS A N     1 
ATOM 2216 C CA    . LYS A 1 856 ? 109.672 137.498 101.332 1.00 144.43 ? 597 LYS A CA    1 
ATOM 2217 C C     . LYS A 1 856 ? 108.437 136.662 101.657 1.00 149.06 ? 597 LYS A C     1 
ATOM 2218 O O     . LYS A 1 856 ? 107.308 137.157 101.561 1.00 152.87 ? 597 LYS A O     1 
ATOM 2219 C CB    . LYS A 1 856 ? 110.106 137.266 99.884  1.00 140.49 ? 597 LYS A CB    1 
ATOM 2220 N N     . ARG A 1 857 ? 108.630 135.394 102.031 1.00 149.40 ? 598 ARG A N     1 
ATOM 2221 C CA    . ARG A 1 857 ? 107.509 134.486 102.260 1.00 150.57 ? 598 ARG A CA    1 
ATOM 2222 C C     . ARG A 1 857 ? 106.734 134.861 103.517 1.00 150.10 ? 598 ARG A C     1 
ATOM 2223 O O     . ARG A 1 857 ? 105.499 134.919 103.506 1.00 151.60 ? 598 ARG A O     1 
ATOM 2224 C CB    . ARG A 1 857 ? 108.024 133.048 102.351 1.00 149.97 ? 598 ARG A CB    1 
ATOM 2225 C CG    . ARG A 1 857 ? 106.937 131.988 102.452 1.00 152.83 ? 598 ARG A CG    1 
ATOM 2226 C CD    . ARG A 1 857 ? 105.962 132.041 101.286 1.00 158.17 ? 598 ARG A CD    1 
ATOM 2227 N NE    . ARG A 1 857 ? 106.639 131.898 100.003 1.00 162.08 ? 598 ARG A NE    1 
ATOM 2228 C CZ    . ARG A 1 857 ? 106.418 132.660 98.940  1.00 163.02 ? 598 ARG A CZ    1 
ATOM 2229 N NH1   . ARG A 1 857 ? 105.533 133.643 98.964  1.00 160.71 ? 598 ARG A NH1   1 
ATOM 2230 N NH2   . ARG A 1 857 ? 107.101 132.427 97.822  1.00 162.05 ? 598 ARG A NH2   1 
ATOM 2231 N N     . PHE A 1 858 ? 107.441 135.124 104.607 1.00 148.42 ? 599 PHE A N     1 
ATOM 2232 C CA    . PHE A 1 858 ? 106.829 135.476 105.878 1.00 149.02 ? 599 PHE A CA    1 
ATOM 2233 C C     . PHE A 1 858 ? 106.886 136.984 106.081 1.00 150.27 ? 599 PHE A C     1 
ATOM 2234 O O     . PHE A 1 858 ? 107.653 137.693 105.427 1.00 147.86 ? 599 PHE A O     1 
ATOM 2235 C CB    . PHE A 1 858 ? 107.523 134.764 107.045 1.00 146.93 ? 599 PHE A CB    1 
ATOM 2236 C CG    . PHE A 1 858 ? 107.316 133.264 107.084 1.00 147.98 ? 599 PHE A CG    1 
ATOM 2237 C CD1   . PHE A 1 858 ? 106.480 132.615 106.185 1.00 150.27 ? 599 PHE A CD1   1 
ATOM 2238 C CD2   . PHE A 1 858 ? 107.976 132.505 108.036 1.00 144.14 ? 599 PHE A CD2   1 
ATOM 2239 C CE1   . PHE A 1 858 ? 106.308 131.239 106.242 1.00 149.35 ? 599 PHE A CE1   1 
ATOM 2240 C CE2   . PHE A 1 858 ? 107.809 131.134 108.096 1.00 142.14 ? 599 PHE A CE2   1 
ATOM 2241 C CZ    . PHE A 1 858 ? 106.975 130.500 107.201 1.00 143.72 ? 599 PHE A CZ    1 
ATOM 2242 N N     . ASP A 1 859 ? 106.048 137.475 106.990 1.00 153.22 ? 600 ASP A N     1 
ATOM 2243 C CA    . ASP A 1 859 ? 106.040 138.900 107.289 1.00 153.37 ? 600 ASP A CA    1 
ATOM 2244 C C     . ASP A 1 859 ? 107.315 139.281 108.030 1.00 150.11 ? 600 ASP A C     1 
ATOM 2245 O O     . ASP A 1 859 ? 107.640 138.701 109.072 1.00 147.64 ? 600 ASP A O     1 
ATOM 2246 C CB    . ASP A 1 859 ? 104.810 139.263 108.113 1.00 154.44 ? 600 ASP A CB    1 
ATOM 2247 N N     . THR A 1 860 ? 108.036 140.260 107.491 1.00 149.33 ? 601 THR A N     1 
ATOM 2248 C CA    . THR A 1 860 ? 109.320 140.680 108.032 1.00 150.64 ? 601 THR A CA    1 
ATOM 2249 C C     . THR A 1 860 ? 109.264 142.144 108.444 1.00 150.75 ? 601 THR A C     1 
ATOM 2250 O O     . THR A 1 860 ? 108.521 142.945 107.869 1.00 150.19 ? 601 THR A O     1 
ATOM 2251 C CB    . THR A 1 860 ? 110.458 140.460 107.015 1.00 148.11 ? 601 THR A CB    1 
ATOM 2252 O OG1   . THR A 1 860 ? 111.701 140.885 107.574 1.00 147.78 ? 601 THR A OG1   1 
ATOM 2253 C CG2   . THR A 1 860 ? 110.199 141.234 105.727 1.00 145.01 ? 601 THR A CG2   1 
ATOM 2254 N N     . LYS A 1 861 ? 110.044 142.480 109.467 1.00 149.25 ? 602 LYS A N     1 
ATOM 2255 C CA    . LYS A 1 861 ? 110.175 143.851 109.935 1.00 145.98 ? 602 LYS A CA    1 
ATOM 2256 C C     . LYS A 1 861 ? 111.459 144.375 109.302 1.00 146.31 ? 602 LYS A C     1 
ATOM 2257 O O     . LYS A 1 861 ? 112.506 143.723 109.385 1.00 147.22 ? 602 LYS A O     1 
ATOM 2258 C CB    . LYS A 1 861 ? 110.228 143.885 111.471 1.00 144.15 ? 602 LYS A CB    1 
ATOM 2259 C CG    . LYS A 1 861 ? 110.882 145.082 112.219 1.00 143.46 ? 602 LYS A CG    1 
ATOM 2260 C CD    . LYS A 1 861 ? 110.499 146.472 111.685 1.00 142.69 ? 602 LYS A CD    1 
ATOM 2261 C CE    . LYS A 1 861 ? 111.198 147.587 112.444 1.00 139.92 ? 602 LYS A CE    1 
ATOM 2262 N NZ    . LYS A 1 861 ? 112.645 147.682 112.110 1.00 141.04 ? 602 LYS A NZ    1 
ATOM 2263 N N     . LYS A 1 862 ? 111.369 145.539 108.662 1.00 145.22 ? 603 LYS A N     1 
ATOM 2264 C CA    . LYS A 1 862 ? 112.448 146.052 107.822 1.00 143.77 ? 603 LYS A CA    1 
ATOM 2265 C C     . LYS A 1 862 ? 113.652 146.442 108.673 1.00 143.65 ? 603 LYS A C     1 
ATOM 2266 O O     . LYS A 1 862 ? 113.611 147.433 109.410 1.00 142.21 ? 603 LYS A O     1 
ATOM 2267 C CB    . LYS A 1 862 ? 111.948 147.242 107.008 1.00 142.62 ? 603 LYS A CB    1 
ATOM 2268 N N     . GLY A 1 863 ? 114.726 145.658 108.573 1.00 142.41 ? 604 GLY A N     1 
ATOM 2269 C CA    . GLY A 1 863 ? 116.016 146.040 109.105 1.00 140.57 ? 604 GLY A CA    1 
ATOM 2270 C C     . GLY A 1 863 ? 116.280 145.720 110.561 1.00 141.36 ? 604 GLY A C     1 
ATOM 2271 O O     . GLY A 1 863 ? 117.322 146.137 111.082 1.00 140.03 ? 604 GLY A O     1 
ATOM 2272 N N     . LYS A 1 864 ? 115.389 145.006 111.240 1.00 143.40 ? 605 LYS A N     1 
ATOM 2273 C CA    . LYS A 1 864 ? 115.593 144.664 112.641 1.00 141.21 ? 605 LYS A CA    1 
ATOM 2274 C C     . LYS A 1 864 ? 115.801 143.156 112.773 1.00 139.39 ? 605 LYS A C     1 
ATOM 2275 O O     . LYS A 1 864 ? 115.596 142.393 111.826 1.00 138.49 ? 605 LYS A O     1 
ATOM 2276 C CB    . LYS A 1 864 ? 114.407 145.140 113.492 1.00 140.00 ? 605 LYS A CB    1 
ATOM 2277 C CG    . LYS A 1 864 ? 114.736 145.420 114.958 1.00 136.76 ? 605 LYS A CG    1 
ATOM 2278 C CD    . LYS A 1 864 ? 113.506 145.349 115.845 1.00 138.16 ? 605 LYS A CD    1 
ATOM 2279 C CE    . LYS A 1 864 ? 113.175 143.911 116.203 1.00 136.96 ? 605 LYS A CE    1 
ATOM 2280 N NZ    . LYS A 1 864 ? 113.988 143.432 117.356 1.00 135.93 ? 605 LYS A NZ    1 
ATOM 2281 N N     . CYS A 1 865 ? 116.229 142.735 113.964 1.00 138.49 ? 606 CYS A N     1 
ATOM 2282 C CA    . CYS A 1 865 ? 116.522 141.330 114.222 1.00 137.76 ? 606 CYS A CA    1 
ATOM 2283 C C     . CYS A 1 865 ? 115.257 140.483 114.151 1.00 138.58 ? 606 CYS A C     1 
ATOM 2284 O O     . CYS A 1 865 ? 114.188 140.887 114.616 1.00 139.12 ? 606 CYS A O     1 
ATOM 2285 C CB    . CYS A 1 865 ? 117.183 141.171 115.591 1.00 137.00 ? 606 CYS A CB    1 
ATOM 2286 S SG    . CYS A 1 865 ? 117.855 139.525 115.917 1.00 129.93 ? 606 CYS A SG    1 
ATOM 2287 N N     . LEU A 1 866 ? 115.389 139.300 113.563 1.00 135.46 ? 607 LEU A N     1 
ATOM 2288 C CA    . LEU A 1 866 ? 114.272 138.414 113.280 1.00 134.05 ? 607 LEU A CA    1 
ATOM 2289 C C     . LEU A 1 866 ? 114.218 137.288 114.312 1.00 131.80 ? 607 LEU A C     1 
ATOM 2290 O O     . LEU A 1 866 ? 115.230 136.913 114.908 1.00 130.11 ? 607 LEU A O     1 
ATOM 2291 C CB    . LEU A 1 866 ? 114.405 137.867 111.854 1.00 131.40 ? 607 LEU A CB    1 
ATOM 2292 C CG    . LEU A 1 866 ? 113.263 137.137 111.153 1.00 130.35 ? 607 LEU A CG    1 
ATOM 2293 C CD1   . LEU A 1 866 ? 113.235 137.536 109.691 1.00 130.17 ? 607 LEU A CD1   1 
ATOM 2294 C CD2   . LEU A 1 866 ? 113.458 135.653 111.264 1.00 129.35 ? 607 LEU A CD2   1 
ATOM 2295 N N     . THR A 1 867 ? 113.019 136.750 114.517 1.00 132.46 ? 608 THR A N     1 
ATOM 2296 C CA    . THR A 1 867 ? 112.761 135.824 115.613 1.00 131.83 ? 608 THR A CA    1 
ATOM 2297 C C     . THR A 1 867 ? 113.197 134.401 115.264 1.00 131.63 ? 608 THR A C     1 
ATOM 2298 O O     . THR A 1 867 ? 113.434 134.059 114.104 1.00 130.39 ? 608 THR A O     1 
ATOM 2299 C CB    . THR A 1 867 ? 111.279 135.836 115.990 1.00 129.80 ? 608 THR A CB    1 
ATOM 2300 N N     . ASP A 1 868 ? 113.292 133.566 116.302 1.00 131.61 ? 609 ASP A N     1 
ATOM 2301 C CA    . ASP A 1 868 ? 113.846 132.223 116.150 1.00 129.68 ? 609 ASP A CA    1 
ATOM 2302 C C     . ASP A 1 868 ? 112.839 131.257 115.534 1.00 129.60 ? 609 ASP A C     1 
ATOM 2303 O O     . ASP A 1 868 ? 113.087 130.682 114.469 1.00 129.96 ? 609 ASP A O     1 
ATOM 2304 C CB    . ASP A 1 868 ? 114.326 131.700 117.507 1.00 125.88 ? 609 ASP A CB    1 
ATOM 2305 N N     . LYS A 1 869 ? 111.701 131.052 116.205 1.00 129.78 ? 610 LYS A N     1 
ATOM 2306 C CA    . LYS A 1 869 ? 110.683 130.147 115.679 1.00 131.34 ? 610 LYS A CA    1 
ATOM 2307 C C     . LYS A 1 869 ? 110.050 130.694 114.407 1.00 133.76 ? 610 LYS A C     1 
ATOM 2308 O O     . LYS A 1 869 ? 109.552 129.921 113.582 1.00 133.11 ? 610 LYS A O     1 
ATOM 2309 C CB    . LYS A 1 869 ? 109.611 129.886 116.737 1.00 130.44 ? 610 LYS A CB    1 
ATOM 2310 N N     . GLU A 1 870 ? 110.053 132.019 114.244 1.00 134.22 ? 611 GLU A N     1 
ATOM 2311 C CA    . GLU A 1 870 ? 109.632 132.632 112.989 1.00 136.45 ? 611 GLU A CA    1 
ATOM 2312 C C     . GLU A 1 870 ? 110.543 132.203 111.842 1.00 137.07 ? 611 GLU A C     1 
ATOM 2313 O O     . GLU A 1 870 ? 110.068 131.909 110.739 1.00 137.88 ? 611 GLU A O     1 
ATOM 2314 C CB    . GLU A 1 870 ? 109.606 134.155 113.170 1.00 137.52 ? 611 GLU A CB    1 
ATOM 2315 C CG    . GLU A 1 870 ? 109.886 135.050 111.963 1.00 140.91 ? 611 GLU A CG    1 
ATOM 2316 C CD    . GLU A 1 870 ? 108.972 134.809 110.782 1.00 143.39 ? 611 GLU A CD    1 
ATOM 2317 O OE1   . GLU A 1 870 ? 107.740 134.751 110.976 1.00 143.25 ? 611 GLU A OE1   1 
ATOM 2318 O OE2   . GLU A 1 870 ? 109.497 134.696 109.657 1.00 143.67 ? 611 GLU A OE2   1 
ATOM 2319 N N     . ALA A 1 871 ? 111.853 132.145 112.088 1.00 135.53 ? 612 ALA A N     1 
ATOM 2320 C CA    . ALA A 1 871 ? 112.774 131.662 111.065 1.00 134.98 ? 612 ALA A CA    1 
ATOM 2321 C C     . ALA A 1 871 ? 112.695 130.151 110.895 1.00 131.73 ? 612 ALA A C     1 
ATOM 2322 O O     . ALA A 1 871 ? 112.963 129.637 109.803 1.00 128.30 ? 612 ALA A O     1 
ATOM 2323 C CB    . ALA A 1 871 ? 114.206 132.072 111.406 1.00 133.32 ? 612 ALA A CB    1 
ATOM 2324 N N     . LYS A 1 872 ? 112.342 129.426 111.960 1.00 132.46 ? 613 LYS A N     1 
ATOM 2325 C CA    . LYS A 1 872 ? 112.410 127.969 111.939 1.00 132.40 ? 613 LYS A CA    1 
ATOM 2326 C C     . LYS A 1 872 ? 111.354 127.333 111.043 1.00 133.87 ? 613 LYS A C     1 
ATOM 2327 O O     . LYS A 1 872 ? 111.555 126.204 110.584 1.00 134.74 ? 613 LYS A O     1 
ATOM 2328 C CB    . LYS A 1 872 ? 112.280 127.422 113.362 1.00 128.88 ? 613 LYS A CB    1 
ATOM 2329 C CG    . LYS A 1 872 ? 112.968 126.085 113.579 1.00 121.97 ? 613 LYS A CG    1 
ATOM 2330 C CD    . LYS A 1 872 ? 112.905 125.663 115.036 1.00 115.76 ? 613 LYS A CD    1 
ATOM 2331 C CE    . LYS A 1 872 ? 113.692 126.616 115.920 1.00 116.03 ? 613 LYS A CE    1 
ATOM 2332 N NZ    . LYS A 1 872 ? 113.432 126.375 117.367 1.00 116.17 ? 613 LYS A NZ    1 
ATOM 2333 N N     . GLU A 1 873 ? 110.241 128.024 110.780 1.00 135.52 ? 614 GLU A N     1 
ATOM 2334 C CA    . GLU A 1 873 ? 109.181 127.425 109.974 1.00 136.47 ? 614 GLU A CA    1 
ATOM 2335 C C     . GLU A 1 873 ? 109.562 127.341 108.501 1.00 134.49 ? 614 GLU A C     1 
ATOM 2336 O O     . GLU A 1 873 ? 109.041 126.485 107.777 1.00 132.12 ? 614 GLU A O     1 
ATOM 2337 C CB    . GLU A 1 873 ? 107.877 128.215 110.132 1.00 136.46 ? 614 GLU A CB    1 
ATOM 2338 C CG    . GLU A 1 873 ? 107.394 128.605 111.559 1.00 136.02 ? 614 GLU A CG    1 
ATOM 2339 C CD    . GLU A 1 873 ? 107.175 127.469 112.581 1.00 139.65 ? 614 GLU A CD    1 
ATOM 2340 O OE1   . GLU A 1 873 ? 107.740 126.359 112.490 1.00 139.35 ? 614 GLU A OE1   1 
ATOM 2341 O OE2   . GLU A 1 873 ? 106.389 127.711 113.522 1.00 143.76 ? 614 GLU A OE2   1 
ATOM 2342 N N     . ALA A 1 874 ? 110.462 128.206 108.041 1.00 133.88 ? 615 ALA A N     1 
ATOM 2343 C CA    . ALA A 1 874 ? 110.852 128.242 106.638 1.00 131.33 ? 615 ALA A CA    1 
ATOM 2344 C C     . ALA A 1 874 ? 111.813 127.091 106.335 1.00 128.94 ? 615 ALA A C     1 
ATOM 2345 O O     . ALA A 1 874 ? 112.081 126.231 107.178 1.00 129.89 ? 615 ALA A O     1 
ATOM 2346 C CB    . ALA A 1 874 ? 111.452 129.604 106.296 1.00 130.21 ? 615 ALA A CB    1 
ATOM 2347 N N     . GLY A 1 875 ? 112.353 127.067 105.119 1.00 127.21 ? 616 GLY A N     1 
ATOM 2348 C CA    . GLY A 1 875 ? 113.216 125.980 104.704 1.00 124.95 ? 616 GLY A CA    1 
ATOM 2349 C C     . GLY A 1 875 ? 114.648 126.152 105.160 1.00 122.47 ? 616 GLY A C     1 
ATOM 2350 O O     . GLY A 1 875 ? 115.417 126.906 104.558 1.00 123.73 ? 616 GLY A O     1 
ATOM 2351 N N     . PHE A 1 876 ? 115.015 125.454 106.232 1.00 116.89 ? 617 PHE A N     1 
ATOM 2352 C CA    . PHE A 1 876 ? 116.374 125.480 106.752 1.00 112.95 ? 617 PHE A CA    1 
ATOM 2353 C C     . PHE A 1 876 ? 116.693 124.112 107.331 1.00 111.26 ? 617 PHE A C     1 
ATOM 2354 O O     . PHE A 1 876 ? 115.821 123.470 107.922 1.00 111.58 ? 617 PHE A O     1 
ATOM 2355 C CB    . PHE A 1 876 ? 116.550 126.556 107.832 1.00 112.21 ? 617 PHE A CB    1 
ATOM 2356 C CG    . PHE A 1 876 ? 116.619 127.957 107.294 1.00 112.87 ? 617 PHE A CG    1 
ATOM 2357 C CD1   . PHE A 1 876 ? 117.619 128.323 106.409 1.00 111.61 ? 617 PHE A CD1   1 
ATOM 2358 C CD2   . PHE A 1 876 ? 115.692 128.911 107.683 1.00 114.89 ? 617 PHE A CD2   1 
ATOM 2359 C CE1   . PHE A 1 876 ? 117.690 129.610 105.914 1.00 111.85 ? 617 PHE A CE1   1 
ATOM 2360 C CE2   . PHE A 1 876 ? 115.758 130.201 107.191 1.00 113.82 ? 617 PHE A CE2   1 
ATOM 2361 C CZ    . PHE A 1 876 ? 116.758 130.549 106.305 1.00 113.07 ? 617 PHE A CZ    1 
ATOM 2362 N N     . CYS A 1 877 ? 117.936 123.670 107.158 1.00 109.81 ? 618 CYS A N     1 
ATOM 2363 C CA    . CYS A 1 877 ? 118.374 122.440 107.801 1.00 105.97 ? 618 CYS A CA    1 
ATOM 2364 C C     . CYS A 1 877 ? 118.449 122.639 109.310 1.00 100.34 ? 618 CYS A C     1 
ATOM 2365 O O     . CYS A 1 877 ? 118.825 123.706 109.805 1.00 96.81  ? 618 CYS A O     1 
ATOM 2366 C CB    . CYS A 1 877 ? 119.731 121.989 107.257 1.00 102.43 ? 618 CYS A CB    1 
ATOM 2367 S SG    . CYS A 1 877 ? 119.823 121.898 105.451 1.00 106.75 ? 618 CYS A SG    1 
ATOM 2368 N N     . ILE A 1 878 ? 118.078 121.595 110.043 1.00 100.23 ? 619 ILE A N     1 
ATOM 2369 C CA    . ILE A 1 878 ? 117.985 121.657 111.496 1.00 99.06  ? 619 ILE A CA    1 
ATOM 2370 C C     . ILE A 1 878 ? 119.271 121.101 112.088 1.00 98.20  ? 619 ILE A C     1 
ATOM 2371 O O     . ILE A 1 878 ? 119.959 120.287 111.457 1.00 96.52  ? 619 ILE A O     1 
ATOM 2372 C CB    . ILE A 1 878 ? 116.738 120.902 112.008 1.00 100.16 ? 619 ILE A CB    1 
ATOM 2373 C CG1   . ILE A 1 878 ? 116.079 121.674 113.151 1.00 99.62  ? 619 ILE A CG1   1 
ATOM 2374 C CG2   . ILE A 1 878 ? 117.058 119.467 112.450 1.00 98.13  ? 619 ILE A CG2   1 
ATOM 2375 C CD1   . ILE A 1 878 ? 115.532 123.015 112.724 1.00 99.35  ? 619 ILE A CD1   1 
ATOM 2376 N N     . LYS A 1 879 ? 119.643 121.600 113.262 1.00 96.49  ? 620 LYS A N     1 
ATOM 2377 C CA    . LYS A 1 879 ? 120.763 121.029 113.992 1.00 93.36  ? 620 LYS A CA    1 
ATOM 2378 C C     . LYS A 1 879 ? 120.267 120.017 115.015 1.00 96.81  ? 620 LYS A C     1 
ATOM 2379 O O     . LYS A 1 879 ? 119.090 119.989 115.380 1.00 98.84  ? 620 LYS A O     1 
ATOM 2380 C CB    . LYS A 1 879 ? 121.601 122.109 114.678 1.00 87.85  ? 620 LYS A CB    1 
ATOM 2381 C CG    . LYS A 1 879 ? 122.177 123.135 113.717 1.00 85.12  ? 620 LYS A CG    1 
ATOM 2382 C CD    . LYS A 1 879 ? 123.462 123.764 114.246 1.00 80.67  ? 620 LYS A CD    1 
ATOM 2383 C CE    . LYS A 1 879 ? 123.307 124.267 115.667 1.00 81.12  ? 620 LYS A CE    1 
ATOM 2384 N NZ    . LYS A 1 879 ? 124.581 124.822 116.195 1.00 70.29  ? 620 LYS A NZ    1 
ATOM 2385 N N     . LYS A 1 880 ? 121.188 119.164 115.460 1.00 94.38  ? 621 LYS A N     1 
ATOM 2386 C CA    . LYS A 1 880 ? 120.830 118.110 116.402 1.00 95.66  ? 621 LYS A CA    1 
ATOM 2387 C C     . LYS A 1 880 ? 120.456 118.673 117.768 1.00 96.01  ? 621 LYS A C     1 
ATOM 2388 O O     . LYS A 1 880 ? 119.494 118.211 118.392 1.00 95.65  ? 621 LYS A O     1 
ATOM 2389 C CB    . LYS A 1 880 ? 121.984 117.117 116.528 1.00 92.88  ? 621 LYS A CB    1 
ATOM 2390 C CG    . LYS A 1 880 ? 121.668 115.882 117.350 1.00 95.19  ? 621 LYS A CG    1 
ATOM 2391 C CD    . LYS A 1 880 ? 122.877 114.965 117.408 1.00 91.76  ? 621 LYS A CD    1 
ATOM 2392 C CE    . LYS A 1 880 ? 123.287 114.525 116.015 1.00 87.54  ? 621 LYS A CE    1 
ATOM 2393 N NZ    . LYS A 1 880 ? 122.240 113.692 115.361 1.00 102.76 ? 621 LYS A NZ    1 
ATOM 2394 N N     . ASN A 1 881 ? 121.190 119.680 118.243 1.00 96.05  ? 622 ASN A N     1 
ATOM 2395 C CA    . ASN A 1 881 ? 121.105 120.103 119.638 1.00 95.99  ? 622 ASN A CA    1 
ATOM 2396 C C     . ASN A 1 881 ? 120.282 121.375 119.836 1.00 98.84  ? 622 ASN A C     1 
ATOM 2397 O O     . ASN A 1 881 ? 119.298 121.365 120.581 1.00 99.78  ? 622 ASN A O     1 
ATOM 2398 C CB    . ASN A 1 881 ? 122.522 120.281 120.204 1.00 94.09  ? 622 ASN A CB    1 
ATOM 2399 C CG    . ASN A 1 881 ? 123.448 121.011 119.249 1.00 92.27  ? 622 ASN A CG    1 
ATOM 2400 O OD1   . ASN A 1 881 ? 123.000 121.756 118.383 1.00 89.64  ? 622 ASN A OD1   1 
ATOM 2401 N ND2   . ASN A 1 881 ? 124.747 120.807 119.413 1.00 90.01  ? 622 ASN A ND2   1 
ATOM 2402 N N     . GLU A 1 882 ? 120.658 122.473 119.181 1.00 99.63  ? 623 GLU A N     1 
ATOM 2403 C CA    . GLU A 1 882 ? 120.093 123.779 119.501 1.00 99.87  ? 623 GLU A CA    1 
ATOM 2404 C C     . GLU A 1 882 ? 118.985 124.188 118.529 1.00 99.81  ? 623 GLU A C     1 
ATOM 2405 O O     . GLU A 1 882 ? 118.202 125.092 118.846 1.00 101.29 ? 623 GLU A O     1 
ATOM 2406 C CB    . GLU A 1 882 ? 121.256 124.806 119.596 1.00 90.35  ? 623 GLU A CB    1 
ATOM 2407 C CG    . GLU A 1 882 ? 121.001 126.332 119.653 1.00 89.89  ? 623 GLU A CG    1 
ATOM 2408 C CD    . GLU A 1 882 ? 120.517 126.987 118.374 1.00 95.85  ? 623 GLU A CD    1 
ATOM 2409 O OE1   . GLU A 1 882 ? 120.582 126.359 117.299 1.00 94.25  ? 623 GLU A OE1   1 
ATOM 2410 O OE2   . GLU A 1 882 ? 120.051 128.140 118.457 1.00 98.20  ? 623 GLU A OE2   1 
ATOM 2411 N N     . LEU A 1 883 ? 118.888 123.518 117.377 1.00 97.50  ? 624 LEU A N     1 
ATOM 2412 C CA    . LEU A 1 883 ? 117.764 123.507 116.420 1.00 101.12 ? 624 LEU A CA    1 
ATOM 2413 C C     . LEU A 1 883 ? 117.640 124.740 115.526 1.00 102.25 ? 624 LEU A C     1 
ATOM 2414 O O     . LEU A 1 883 ? 116.524 125.043 115.090 1.00 109.23 ? 624 LEU A O     1 
ATOM 2415 C CB    . LEU A 1 883 ? 116.404 123.271 117.098 1.00 106.15 ? 624 LEU A CB    1 
ATOM 2416 C CG    . LEU A 1 883 ? 116.241 122.148 118.131 1.00 102.36 ? 624 LEU A CG    1 
ATOM 2417 C CD1   . LEU A 1 883 ? 114.789 122.034 118.583 1.00 106.88 ? 624 LEU A CD1   1 
ATOM 2418 C CD2   . LEU A 1 883 ? 116.755 120.824 117.583 1.00 97.15  ? 624 LEU A CD2   1 
ATOM 2419 N N     . VAL A 1 884 ? 118.713 125.486 115.268 1.00 95.31  ? 625 VAL A N     1 
ATOM 2420 C CA    . VAL A 1 884 ? 118.759 126.379 114.115 1.00 96.01  ? 625 VAL A CA    1 
ATOM 2421 C C     . VAL A 1 884 ? 120.180 126.363 113.560 1.00 93.28  ? 625 VAL A C     1 
ATOM 2422 O O     . VAL A 1 884 ? 121.156 126.215 114.301 1.00 93.58  ? 625 VAL A O     1 
ATOM 2423 C CB    . VAL A 1 884 ? 118.277 127.815 114.453 1.00 95.00  ? 625 VAL A CB    1 
ATOM 2424 C CG1   . VAL A 1 884 ? 119.265 128.570 115.316 1.00 92.89  ? 625 VAL A CG1   1 
ATOM 2425 C CG2   . VAL A 1 884 ? 117.932 128.581 113.194 1.00 96.59  ? 625 VAL A CG2   1 
ATOM 2426 N N     . MET A 1 885 ? 120.292 126.493 112.238 1.00 92.19  ? 626 MET A N     1 
ATOM 2427 C CA    . MET A 1 885 ? 121.585 126.348 111.582 1.00 88.85  ? 626 MET A CA    1 
ATOM 2428 C C     . MET A 1 885 ? 122.470 127.576 111.813 1.00 91.22  ? 626 MET A C     1 
ATOM 2429 O O     . MET A 1 885 ? 122.102 128.537 112.495 1.00 92.13  ? 626 MET A O     1 
ATOM 2430 C CB    . MET A 1 885 ? 121.427 126.125 110.080 1.00 87.47  ? 626 MET A CB    1 
ATOM 2431 C CG    . MET A 1 885 ? 120.797 127.298 109.370 1.00 91.99  ? 626 MET A CG    1 
ATOM 2432 S SD    . MET A 1 885 ? 120.819 127.202 107.572 1.00 105.90 ? 626 MET A SD    1 
ATOM 2433 C CE    . MET A 1 885 ? 120.805 125.443 107.307 1.00 100.74 ? 626 MET A CE    1 
ATOM 2434 N N     . SER A 1 886 ? 123.663 127.539 111.221 1.00 90.06  ? 627 SER A N     1 
ATOM 2435 C CA    . SER A 1 886 ? 124.637 128.616 111.312 1.00 85.63  ? 627 SER A CA    1 
ATOM 2436 C C     . SER A 1 886 ? 125.191 128.918 109.927 1.00 82.70  ? 627 SER A C     1 
ATOM 2437 O O     . SER A 1 886 ? 125.526 128.001 109.174 1.00 83.29  ? 627 SER A O     1 
ATOM 2438 C CB    . SER A 1 886 ? 125.776 128.243 112.262 1.00 84.49  ? 627 SER A CB    1 
ATOM 2439 O OG    . SER A 1 886 ? 126.558 127.193 111.717 1.00 85.90  ? 627 SER A OG    1 
ATOM 2440 N N     . LEU A 1 887 ? 125.288 130.205 109.598 1.00 81.54  ? 628 LEU A N     1 
ATOM 2441 C CA    . LEU A 1 887 ? 125.774 130.652 108.300 1.00 79.33  ? 628 LEU A CA    1 
ATOM 2442 C C     . LEU A 1 887 ? 126.917 131.633 108.494 1.00 78.08  ? 628 LEU A C     1 
ATOM 2443 O O     . LEU A 1 887 ? 126.842 132.520 109.350 1.00 80.31  ? 628 LEU A O     1 
ATOM 2444 C CB    . LEU A 1 887 ? 124.665 131.324 107.486 1.00 82.86  ? 628 LEU A CB    1 
ATOM 2445 C CG    . LEU A 1 887 ? 123.447 130.475 107.132 1.00 93.69  ? 628 LEU A CG    1 
ATOM 2446 C CD1   . LEU A 1 887 ? 122.405 131.320 106.419 1.00 96.65  ? 628 LEU A CD1   1 
ATOM 2447 C CD2   . LEU A 1 887 ? 123.859 129.286 106.285 1.00 97.65  ? 628 LEU A CD2   1 
ATOM 2448 N N     . LYS A 1 888 ? 127.970 131.478 107.696 1.00 77.95  ? 629 LYS A N     1 
ATOM 2449 C CA    . LYS A 1 888 ? 129.099 132.394 107.780 1.00 75.87  ? 629 LYS A CA    1 
ATOM 2450 C C     . LYS A 1 888 ? 128.714 133.756 107.219 1.00 76.06  ? 629 LYS A C     1 
ATOM 2451 O O     . LYS A 1 888 ? 128.100 133.851 106.153 1.00 86.40  ? 629 LYS A O     1 
ATOM 2452 C CB    . LYS A 1 888 ? 130.308 131.836 107.033 1.00 76.34  ? 629 LYS A CB    1 
ATOM 2453 C CG    . LYS A 1 888 ? 130.895 130.573 107.643 1.00 80.16  ? 629 LYS A CG    1 
ATOM 2454 C CD    . LYS A 1 888 ? 131.995 129.973 106.777 1.00 88.00  ? 629 LYS A CD    1 
ATOM 2455 C CE    . LYS A 1 888 ? 132.913 131.045 106.214 1.00 85.89  ? 629 LYS A CE    1 
ATOM 2456 N NZ    . LYS A 1 888 ? 133.794 130.520 105.141 1.00 96.12  ? 629 LYS A NZ    1 
ATOM 2457 N N     . CYS A 1 889 ? 129.071 134.808 107.945 1.00 68.14  ? 630 CYS A N     1 
ATOM 2458 C CA    . CYS A 1 889 ? 128.738 136.174 107.579 1.00 74.45  ? 630 CYS A CA    1 
ATOM 2459 C C     . CYS A 1 889 ? 130.007 137.009 107.513 1.00 77.73  ? 630 CYS A C     1 
ATOM 2460 O O     . CYS A 1 889 ? 130.988 136.727 108.206 1.00 78.63  ? 630 CYS A O     1 
ATOM 2461 C CB    . CYS A 1 889 ? 127.757 136.785 108.584 1.00 71.59  ? 630 CYS A CB    1 
ATOM 2462 S SG    . CYS A 1 889 ? 127.164 138.437 108.177 1.00 85.85  ? 630 CYS A SG    1 
ATOM 2463 N N     . SER A 1 890 ? 129.984 138.039 106.674 1.00 84.31  ? 631 SER A N     1 
ATOM 2464 C CA    . SER A 1 890 ? 131.125 138.932 106.530 1.00 80.34  ? 631 SER A CA    1 
ATOM 2465 C C     . SER A 1 890 ? 130.989 140.115 107.478 1.00 81.76  ? 631 SER A C     1 
ATOM 2466 O O     . SER A 1 890 ? 129.907 140.689 107.627 1.00 88.11  ? 631 SER A O     1 
ATOM 2467 C CB    . SER A 1 890 ? 131.251 139.428 105.089 1.00 83.61  ? 631 SER A CB    1 
ATOM 2468 O OG    . SER A 1 890 ? 131.237 138.347 104.175 1.00 87.79  ? 631 SER A OG    1 
ATOM 2469 N N     . ILE A 1 891 ? 132.098 140.475 108.116 1.00 79.28  ? 632 ILE A N     1 
ATOM 2470 C CA    . ILE A 1 891 ? 132.141 141.577 109.068 1.00 83.51  ? 632 ILE A CA    1 
ATOM 2471 C C     . ILE A 1 891 ? 132.591 142.826 108.326 1.00 89.70  ? 632 ILE A C     1 
ATOM 2472 O O     . ILE A 1 891 ? 133.608 142.806 107.622 1.00 92.90  ? 632 ILE A O     1 
ATOM 2473 C CB    . ILE A 1 891 ? 133.081 141.259 110.242 1.00 79.31  ? 632 ILE A CB    1 
ATOM 2474 C CG1   . ILE A 1 891 ? 132.734 139.897 110.848 1.00 72.38  ? 632 ILE A CG1   1 
ATOM 2475 C CG2   . ILE A 1 891 ? 133.021 142.359 111.292 1.00 81.49  ? 632 ILE A CG2   1 
ATOM 2476 C CD1   . ILE A 1 891 ? 131.488 139.899 111.704 1.00 72.15  ? 632 ILE A CD1   1 
ATOM 2477 N N     . LYS A 1 892 ? 131.841 143.911 108.483 1.00 93.30  ? 633 LYS A N     1 
ATOM 2478 C CA    . LYS A 1 892 ? 132.070 145.137 107.735 1.00 100.64 ? 633 LYS A CA    1 
ATOM 2479 C C     . LYS A 1 892 ? 132.555 146.256 108.646 1.00 105.31 ? 633 LYS A C     1 
ATOM 2480 O O     . LYS A 1 892 ? 132.392 146.215 109.868 1.00 103.44 ? 633 LYS A O     1 
ATOM 2481 C CB    . LYS A 1 892 ? 130.794 145.581 107.008 1.00 100.99 ? 633 LYS A CB    1 
ATOM 2482 C CG    . LYS A 1 892 ? 130.559 144.931 105.645 1.00 100.86 ? 633 LYS A CG    1 
ATOM 2483 C CD    . LYS A 1 892 ? 131.861 144.604 104.925 1.00 99.57  ? 633 LYS A CD    1 
ATOM 2484 C CE    . LYS A 1 892 ? 131.618 143.709 103.722 1.00 102.54 ? 633 LYS A CE    1 
ATOM 2485 N NZ    . LYS A 1 892 ? 132.894 143.195 103.154 1.00 101.23 ? 633 LYS A NZ    1 
ATOM 2486 N N     . GLY A 1 893 ? 133.166 147.262 108.020 1.00 107.96 ? 634 GLY A N     1 
ATOM 2487 C CA    . GLY A 1 893 ? 133.585 148.469 108.696 1.00 107.87 ? 634 GLY A CA    1 
ATOM 2488 C C     . GLY A 1 893 ? 134.967 148.426 109.312 1.00 108.81 ? 634 GLY A C     1 
ATOM 2489 O O     . GLY A 1 893 ? 135.502 149.487 109.660 1.00 107.69 ? 634 GLY A O     1 
ATOM 2490 N N     . THR A 1 894 ? 135.565 147.244 109.456 1.00 108.38 ? 635 THR A N     1 
ATOM 2491 C CA    . THR A 1 894 ? 136.865 147.099 110.097 1.00 103.14 ? 635 THR A CA    1 
ATOM 2492 C C     . THR A 1 894 ? 137.744 146.188 109.253 1.00 95.46  ? 635 THR A C     1 
ATOM 2493 O O     . THR A 1 894 ? 137.257 145.422 108.418 1.00 95.67  ? 635 THR A O     1 
ATOM 2494 C CB    . THR A 1 894 ? 136.747 146.535 111.520 1.00 100.51 ? 635 THR A CB    1 
ATOM 2495 O OG1   . THR A 1 894 ? 136.024 145.299 111.487 1.00 100.41 ? 635 THR A OG1   1 
ATOM 2496 C CG2   . THR A 1 894 ? 136.034 147.520 112.441 1.00 100.21 ? 635 THR A CG2   1 
ATOM 2497 N N     . GLY A 1 895 ? 139.052 146.276 109.485 1.00 88.27  ? 636 GLY A N     1 
ATOM 2498 C CA    . GLY A 1 895 ? 140.009 145.539 108.694 1.00 89.80  ? 636 GLY A CA    1 
ATOM 2499 C C     . GLY A 1 895 ? 141.215 145.071 109.485 1.00 87.94  ? 636 GLY A C     1 
ATOM 2500 O O     . GLY A 1 895 ? 141.172 144.945 110.712 1.00 84.04  ? 636 GLY A O     1 
ATOM 2501 N N     . PRO A 1 896 ? 142.323 144.799 108.785 1.00 87.13  ? 637 PRO A N     1 
ATOM 2502 C CA    . PRO A 1 896 ? 143.528 144.287 109.462 1.00 82.65  ? 637 PRO A CA    1 
ATOM 2503 C C     . PRO A 1 896 ? 144.233 145.299 110.355 1.00 82.90  ? 637 PRO A C     1 
ATOM 2504 O O     . PRO A 1 896 ? 145.210 144.926 111.016 1.00 82.76  ? 637 PRO A O     1 
ATOM 2505 C CB    . PRO A 1 896 ? 144.435 143.875 108.296 1.00 80.12  ? 637 PRO A CB    1 
ATOM 2506 C CG    . PRO A 1 896 ? 143.502 143.615 107.167 1.00 81.37  ? 637 PRO A CG    1 
ATOM 2507 C CD    . PRO A 1 896 ? 142.402 144.626 107.325 1.00 84.67  ? 637 PRO A CD    1 
ATOM 2508 N N     . GLY A 1 897 ? 143.786 146.555 110.396 1.00 83.52  ? 638 GLY A N     1 
ATOM 2509 C CA    . GLY A 1 897 ? 144.437 147.559 111.219 1.00 82.37  ? 638 GLY A CA    1 
ATOM 2510 C C     . GLY A 1 897 ? 144.237 147.386 112.711 1.00 83.69  ? 638 GLY A C     1 
ATOM 2511 O O     . GLY A 1 897 ? 144.926 148.056 113.488 1.00 84.61  ? 638 GLY A O     1 
ATOM 2512 N N     . GLN A 1 898 ? 143.317 146.514 113.130 1.00 78.11  ? 639 GLN A N     1 
ATOM 2513 C CA    . GLN A 1 898 ? 143.062 146.279 114.541 1.00 73.01  ? 639 GLN A CA    1 
ATOM 2514 C C     . GLN A 1 898 ? 143.253 144.833 114.971 1.00 70.52  ? 639 GLN A C     1 
ATOM 2515 O O     . GLN A 1 898 ? 143.207 144.558 116.174 1.00 69.32  ? 639 GLN A O     1 
ATOM 2516 C CB    . GLN A 1 898 ? 141.630 146.700 114.910 1.00 73.52  ? 639 GLN A CB    1 
ATOM 2517 C CG    . GLN A 1 898 ? 141.127 147.934 114.196 1.00 78.86  ? 639 GLN A CG    1 
ATOM 2518 C CD    . GLN A 1 898 ? 139.670 148.211 114.487 1.00 87.59  ? 639 GLN A CD    1 
ATOM 2519 O OE1   . GLN A 1 898 ? 138.803 147.389 114.201 1.00 84.58  ? 639 GLN A OE1   1 
ATOM 2520 N NE2   . GLN A 1 898 ? 139.390 149.376 115.058 1.00 97.72  ? 639 GLN A NE2   1 
ATOM 2521 N N     . MET A 1 899 ? 143.467 143.908 114.042 1.00 68.93  ? 640 MET A N     1 
ATOM 2522 C CA    . MET A 1 899 ? 143.382 142.491 114.363 1.00 61.96  ? 640 MET A CA    1 
ATOM 2523 C C     . MET A 1 899 ? 144.630 142.017 115.092 1.00 57.32  ? 640 MET A C     1 
ATOM 2524 O O     . MET A 1 899 ? 145.753 142.205 114.614 1.00 60.55  ? 640 MET A O     1 
ATOM 2525 C CB    . MET A 1 899 ? 143.165 141.675 113.092 1.00 67.21  ? 640 MET A CB    1 
ATOM 2526 C CG    . MET A 1 899 ? 141.913 142.084 112.350 1.00 72.50  ? 640 MET A CG    1 
ATOM 2527 S SD    . MET A 1 899 ? 140.629 142.574 113.512 1.00 75.35  ? 640 MET A SD    1 
ATOM 2528 C CE    . MET A 1 899 ? 139.184 142.485 112.476 1.00 73.23  ? 640 MET A CE    1 
ATOM 2529 N N     . ILE A 1 900 ? 144.425 141.402 116.254 1.00 55.10  ? 641 ILE A N     1 
ATOM 2530 C CA    . ILE A 1 900 ? 145.488 140.774 117.022 1.00 53.12  ? 641 ILE A CA    1 
ATOM 2531 C C     . ILE A 1 900 ? 145.220 139.278 117.069 1.00 47.81  ? 641 ILE A C     1 
ATOM 2532 O O     . ILE A 1 900 ? 144.102 138.816 116.837 1.00 52.89  ? 641 ILE A O     1 
ATOM 2533 C CB    . ILE A 1 900 ? 145.614 141.356 118.444 1.00 54.29  ? 641 ILE A CB    1 
ATOM 2534 C CG1   . ILE A 1 900 ? 144.460 140.883 119.326 1.00 49.93  ? 641 ILE A CG1   1 
ATOM 2535 C CG2   . ILE A 1 900 ? 145.678 142.867 118.394 1.00 60.42  ? 641 ILE A CG2   1 
ATOM 2536 C CD1   . ILE A 1 900 ? 144.561 141.346 120.758 1.00 54.09  ? 641 ILE A CD1   1 
ATOM 2537 N N     . ARG A 1 901 ? 146.269 138.516 117.360 1.00 42.39  ? 642 ARG A N     1 
ATOM 2538 C CA    . ARG A 1 901 ? 146.196 137.058 117.337 1.00 42.05  ? 642 ARG A CA    1 
ATOM 2539 C C     . ARG A 1 901 ? 146.773 136.516 118.639 1.00 45.62  ? 642 ARG A C     1 
ATOM 2540 O O     . ARG A 1 901 ? 147.993 136.480 118.816 1.00 50.02  ? 642 ARG A O     1 
ATOM 2541 C CB    . ARG A 1 901 ? 146.936 136.495 116.131 1.00 44.89  ? 642 ARG A CB    1 
ATOM 2542 C CG    . ARG A 1 901 ? 146.784 134.997 115.961 1.00 48.97  ? 642 ARG A CG    1 
ATOM 2543 C CD    . ARG A 1 901 ? 147.594 134.493 114.784 1.00 49.63  ? 642 ARG A CD    1 
ATOM 2544 N NE    . ARG A 1 901 ? 147.102 135.035 113.524 1.00 48.61  ? 642 ARG A NE    1 
ATOM 2545 C CZ    . ARG A 1 901 ? 146.139 134.486 112.797 1.00 55.33  ? 642 ARG A CZ    1 
ATOM 2546 N NH1   . ARG A 1 901 ? 145.534 133.373 113.179 1.00 55.73  ? 642 ARG A NH1   1 
ATOM 2547 N NH2   . ARG A 1 901 ? 145.771 135.070 111.662 1.00 60.66  ? 642 ARG A NH2   1 
ATOM 2548 N N     . ILE A 1 902 ? 145.895 136.086 119.539 1.00 43.21  ? 643 ILE A N     1 
ATOM 2549 C CA    . ILE A 1 902 ? 146.283 135.471 120.801 1.00 42.42  ? 643 ILE A CA    1 
ATOM 2550 C C     . ILE A 1 902 ? 145.992 133.985 120.672 1.00 45.93  ? 643 ILE A C     1 
ATOM 2551 O O     . ILE A 1 902 ? 144.825 133.580 120.598 1.00 50.11  ? 643 ILE A O     1 
ATOM 2552 C CB    . ILE A 1 902 ? 145.533 136.084 121.989 1.00 41.56  ? 643 ILE A CB    1 
ATOM 2553 C CG1   . ILE A 1 902 ? 145.939 137.545 122.178 1.00 43.25  ? 643 ILE A CG1   1 
ATOM 2554 C CG2   . ILE A 1 902 ? 145.809 135.294 123.253 1.00 41.44  ? 643 ILE A CG2   1 
ATOM 2555 C CD1   . ILE A 1 902 ? 145.005 138.323 123.068 1.00 43.91  ? 643 ILE A CD1   1 
ATOM 2556 N N     . ASN A 1 903 ? 147.054 133.176 120.671 1.00 44.89  ? 644 ASN A N     1 
ATOM 2557 C CA    . ASN A 1 903 ? 147.027 131.744 120.325 1.00 42.07  ? 644 ASN A CA    1 
ATOM 2558 C C     . ASN A 1 903 ? 146.351 131.612 118.960 1.00 45.42  ? 644 ASN A C     1 
ATOM 2559 O O     . ASN A 1 903 ? 146.714 132.348 118.033 1.00 51.84  ? 644 ASN A O     1 
ATOM 2560 C CB    . ASN A 1 903 ? 146.395 130.940 121.455 1.00 41.81  ? 644 ASN A CB    1 
ATOM 2561 C CG    . ASN A 1 903 ? 147.105 131.138 122.776 1.00 46.90  ? 644 ASN A CG    1 
ATOM 2562 O OD1   . ASN A 1 903 ? 148.334 131.173 122.833 1.00 54.12  ? 644 ASN A OD1   1 
ATOM 2563 N ND2   . ASN A 1 903 ? 146.335 131.270 123.849 1.00 49.49  ? 644 ASN A ND2   1 
ATOM 2564 N N     . ASN A 1 904 ? 145.379 130.718 118.790 1.00 39.50  ? 645 ASN A N     1 
ATOM 2565 C CA    . ASN A 1 904 ? 144.738 130.553 117.493 1.00 39.75  ? 645 ASN A CA    1 
ATOM 2566 C C     . ASN A 1 904 ? 143.717 131.638 117.187 1.00 39.65  ? 645 ASN A C     1 
ATOM 2567 O O     . ASN A 1 904 ? 143.464 131.916 116.011 1.00 45.52  ? 645 ASN A O     1 
ATOM 2568 C CB    . ASN A 1 904 ? 144.066 129.182 117.413 1.00 44.00  ? 645 ASN A CB    1 
ATOM 2569 C CG    . ASN A 1 904 ? 142.873 129.063 118.335 1.00 42.63  ? 645 ASN A CG    1 
ATOM 2570 O OD1   . ASN A 1 904 ? 143.025 128.839 119.533 1.00 46.79  ? 645 ASN A OD1   1 
ATOM 2571 N ND2   . ASN A 1 904 ? 141.678 129.217 117.782 1.00 41.39  ? 645 ASN A ND2   1 
ATOM 2572 N N     . ASN A 1 905 ? 143.134 132.259 118.204 1.00 36.75  ? 646 ASN A N     1 
ATOM 2573 C CA    . ASN A 1 905 ? 142.006 133.152 117.997 1.00 40.47  ? 646 ASN A CA    1 
ATOM 2574 C C     . ASN A 1 905 ? 142.465 134.520 117.506 1.00 41.77  ? 646 ASN A C     1 
ATOM 2575 O O     . ASN A 1 905 ? 143.563 134.984 117.824 1.00 44.64  ? 646 ASN A O     1 
ATOM 2576 C CB    . ASN A 1 905 ? 141.216 133.307 119.293 1.00 40.38  ? 646 ASN A CB    1 
ATOM 2577 C CG    . ASN A 1 905 ? 140.871 131.980 119.924 1.00 42.10  ? 646 ASN A CG    1 
ATOM 2578 O OD1   . ASN A 1 905 ? 140.432 131.054 119.246 1.00 44.03  ? 646 ASN A OD1   1 
ATOM 2579 N ND2   . ASN A 1 905 ? 141.077 131.876 121.229 1.00 43.51  ? 646 ASN A ND2   1 
ATOM 2580 N N     . VAL A 1 906 ? 141.605 135.166 116.722 1.00 42.49  ? 647 VAL A N     1 
ATOM 2581 C CA    . VAL A 1 906 ? 141.831 136.516 116.216 1.00 41.86  ? 647 VAL A CA    1 
ATOM 2582 C C     . VAL A 1 906 ? 140.682 137.390 116.695 1.00 47.00  ? 647 VAL A C     1 
ATOM 2583 O O     . VAL A 1 906 ? 139.514 137.078 116.434 1.00 55.51  ? 647 VAL A O     1 
ATOM 2584 C CB    . VAL A 1 906 ? 141.930 136.542 114.683 1.00 38.35  ? 647 VAL A CB    1 
ATOM 2585 C CG1   . VAL A 1 906 ? 142.066 137.968 114.187 1.00 44.39  ? 647 VAL A CG1   1 
ATOM 2586 C CG2   . VAL A 1 906 ? 143.098 135.698 114.213 1.00 40.79  ? 647 VAL A CG2   1 
ATOM 2587 N N     . PHE A 1 907 ? 141.003 138.483 117.380 1.00 41.97  ? 648 PHE A N     1 
ATOM 2588 C CA    . PHE A 1 907 ? 139.989 139.344 117.970 1.00 42.72  ? 648 PHE A CA    1 
ATOM 2589 C C     . PHE A 1 907 ? 139.999 140.720 117.318 1.00 49.41  ? 648 PHE A C     1 
ATOM 2590 O O     . PHE A 1 907 ? 140.883 141.064 116.531 1.00 57.60  ? 648 PHE A O     1 
ATOM 2591 C CB    . PHE A 1 907 ? 140.185 139.510 119.482 1.00 49.46  ? 648 PHE A CB    1 
ATOM 2592 C CG    . PHE A 1 907 ? 140.258 138.219 120.251 1.00 48.83  ? 648 PHE A CG    1 
ATOM 2593 C CD1   . PHE A 1 907 ? 141.446 137.514 120.351 1.00 46.58  ? 648 PHE A CD1   1 
ATOM 2594 C CD2   . PHE A 1 907 ? 139.129 137.705 120.863 1.00 47.73  ? 648 PHE A CD2   1 
ATOM 2595 C CE1   . PHE A 1 907 ? 141.511 136.339 121.063 1.00 44.95  ? 648 PHE A CE1   1 
ATOM 2596 C CE2   . PHE A 1 907 ? 139.190 136.525 121.575 1.00 46.55  ? 648 PHE A CE2   1 
ATOM 2597 C CZ    . PHE A 1 907 ? 140.381 135.841 121.672 1.00 43.80  ? 648 PHE A CZ    1 
ATOM 2598 N N     . LYS A 1 908 ? 138.985 141.506 117.666 1.00 51.26  ? 649 LYS A N     1 
ATOM 2599 C CA    . LYS A 1 908 ? 138.880 142.907 117.277 1.00 59.76  ? 649 LYS A CA    1 
ATOM 2600 C C     . LYS A 1 908 ? 139.311 143.780 118.446 1.00 61.19  ? 649 LYS A C     1 
ATOM 2601 O O     . LYS A 1 908 ? 138.681 143.749 119.507 1.00 65.02  ? 649 LYS A O     1 
ATOM 2602 C CB    . LYS A 1 908 ? 137.448 143.250 116.875 1.00 65.05  ? 649 LYS A CB    1 
ATOM 2603 C CG    . LYS A 1 908 ? 137.039 142.785 115.500 1.00 66.61  ? 649 LYS A CG    1 
ATOM 2604 C CD    . LYS A 1 908 ? 135.849 143.587 115.002 1.00 74.27  ? 649 LYS A CD    1 
ATOM 2605 C CE    . LYS A 1 908 ? 136.086 145.081 115.146 1.00 82.23  ? 649 LYS A CE    1 
ATOM 2606 N NZ    . LYS A 1 908 ? 134.809 145.848 115.202 1.00 90.51  ? 649 LYS A NZ    1 
ATOM 2607 N N     . THR A 1 909 ? 140.359 144.572 118.247 1.00 59.26  ? 650 THR A N     1 
ATOM 2608 C CA    . THR A 1 909 ? 140.848 145.432 119.316 1.00 64.65  ? 650 THR A CA    1 
ATOM 2609 C C     . THR A 1 909 ? 139.912 146.618 119.509 1.00 70.68  ? 650 THR A C     1 
ATOM 2610 O O     . THR A 1 909 ? 139.600 147.341 118.559 1.00 73.46  ? 650 THR A O     1 
ATOM 2611 C CB    . THR A 1 909 ? 142.263 145.912 119.003 1.00 73.94  ? 650 THR A CB    1 
ATOM 2612 O OG1   . THR A 1 909 ? 143.170 144.812 119.126 1.00 70.75  ? 650 THR A OG1   1 
ATOM 2613 C CG2   . THR A 1 909 ? 142.687 147.014 119.957 1.00 83.14  ? 650 THR A CG2   1 
ATOM 2614 N N     . ASN A 1 910 ? 139.463 146.814 120.749 1.00 78.01  ? 651 ASN A N     1 
ATOM 2615 C CA    . ASN A 1 910 ? 138.505 147.870 121.044 1.00 85.86  ? 651 ASN A CA    1 
ATOM 2616 C C     . ASN A 1 910 ? 139.153 149.249 121.086 1.00 90.53  ? 651 ASN A C     1 
ATOM 2617 O O     . ASN A 1 910 ? 138.519 150.236 120.700 1.00 94.12  ? 651 ASN A O     1 
ATOM 2618 C CB    . ASN A 1 910 ? 137.808 147.574 122.374 1.00 87.76  ? 651 ASN A CB    1 
ATOM 2619 C CG    . ASN A 1 910 ? 136.662 148.522 122.656 1.00 98.64  ? 651 ASN A CG    1 
ATOM 2620 O OD1   . ASN A 1 910 ? 136.784 149.438 123.469 1.00 101.41 ? 651 ASN A OD1   1 
ATOM 2621 N ND2   . ASN A 1 910 ? 135.538 148.304 121.985 1.00 100.60 ? 651 ASN A ND2   1 
ATOM 2622 N N     . VAL A 1 911 ? 140.404 149.341 121.538 1.00 88.87  ? 652 VAL A N     1 
ATOM 2623 C CA    . VAL A 1 911 ? 141.019 150.647 121.753 1.00 94.55  ? 652 VAL A CA    1 
ATOM 2624 C C     . VAL A 1 911 ? 141.690 151.212 120.506 1.00 101.72 ? 652 VAL A C     1 
ATOM 2625 O O     . VAL A 1 911 ? 141.929 152.428 120.454 1.00 106.45 ? 652 VAL A O     1 
ATOM 2626 C CB    . VAL A 1 911 ? 142.037 150.590 122.907 1.00 94.47  ? 652 VAL A CB    1 
ATOM 2627 C CG1   . VAL A 1 911 ? 141.335 150.259 124.213 1.00 91.10  ? 652 VAL A CG1   1 
ATOM 2628 C CG2   . VAL A 1 911 ? 143.127 149.575 122.615 1.00 92.84  ? 652 VAL A CG2   1 
ATOM 2629 N N     . HIS A 1 912 ? 141.986 150.372 119.509 1.00 102.99 ? 653 HIS A N     1 
ATOM 2630 C CA    . HIS A 1 912 ? 142.610 150.752 118.225 1.00 108.00 ? 653 HIS A CA    1 
ATOM 2631 C C     . HIS A 1 912 ? 143.950 151.417 118.544 1.00 115.49 ? 653 HIS A C     1 
ATOM 2632 O O     . HIS A 1 912 ? 144.746 150.834 119.298 1.00 114.84 ? 653 HIS A O     1 
ATOM 2633 C CB    . HIS A 1 912 ? 141.618 151.580 117.404 1.00 105.68 ? 653 HIS A CB    1 
ATOM 2634 C CG    . HIS A 1 912 ? 142.063 151.859 116.001 1.00 107.03 ? 653 HIS A CG    1 
ATOM 2635 N ND1   . HIS A 1 912 ? 142.373 150.860 115.104 1.00 105.68 ? 653 HIS A ND1   1 
ATOM 2636 C CD2   . HIS A 1 912 ? 142.243 153.026 115.339 1.00 110.86 ? 653 HIS A CD2   1 
ATOM 2637 C CE1   . HIS A 1 912 ? 142.729 151.399 113.952 1.00 108.35 ? 653 HIS A CE1   1 
ATOM 2638 N NE2   . HIS A 1 912 ? 142.658 152.712 114.068 1.00 112.22 ? 653 HIS A NE2   1 
ATOM 2639 N N     . ASN A 1 913 ? 144.246 152.598 118.009 1.00 118.46 ? 654 ASN A N     1 
ATOM 2640 C CA    . ASN A 1 913 ? 145.456 153.312 118.384 1.00 116.93 ? 654 ASN A CA    1 
ATOM 2641 C C     . ASN A 1 913 ? 145.317 153.892 119.787 1.00 113.81 ? 654 ASN A C     1 
ATOM 2642 O O     . ASN A 1 913 ? 144.236 154.316 120.205 1.00 113.24 ? 654 ASN A O     1 
ATOM 2643 C CB    . ASN A 1 913 ? 145.752 154.425 117.380 1.00 118.74 ? 654 ASN A CB    1 
ATOM 2644 C CG    . ASN A 1 913 ? 146.021 153.895 115.985 1.00 117.61 ? 654 ASN A CG    1 
ATOM 2645 O OD1   . ASN A 1 913 ? 146.136 152.687 115.780 1.00 116.41 ? 654 ASN A OD1   1 
ATOM 2646 N ND2   . ASN A 1 913 ? 146.124 154.799 115.017 1.00 117.27 ? 654 ASN A ND2   1 
ATOM 2647 N N     . VAL A 1 914 ? 146.425 153.904 120.518 1.00 111.94 ? 655 VAL A N     1 
ATOM 2648 C CA    . VAL A 1 914 ? 146.424 154.420 121.880 1.00 116.86 ? 655 VAL A CA    1 
ATOM 2649 C C     . VAL A 1 914 ? 146.485 155.946 121.831 1.00 122.14 ? 655 VAL A C     1 
ATOM 2650 O O     . VAL A 1 914 ? 146.076 156.642 122.760 1.00 125.11 ? 655 VAL A O     1 
ATOM 2651 C CB    . VAL A 1 914 ? 147.590 153.822 122.707 1.00 111.39 ? 655 VAL A CB    1 
ATOM 2652 C CG1   . VAL A 1 914 ? 148.930 154.379 122.248 1.00 110.65 ? 655 VAL A CG1   1 
ATOM 2653 C CG2   . VAL A 1 914 ? 147.377 154.044 124.202 1.00 108.45 ? 655 VAL A CG2   1 
ATOM 2654 N N     . ARG A 1 931 ? 149.971 155.526 116.978 1.00 110.47 ? 672 ARG A N     1 
ATOM 2655 C CA    . ARG A 1 931 ? 150.705 154.805 118.011 1.00 111.50 ? 672 ARG A CA    1 
ATOM 2656 C C     . ARG A 1 931 ? 149.883 153.636 118.540 1.00 111.47 ? 672 ARG A C     1 
ATOM 2657 O O     . ARG A 1 931 ? 148.745 153.812 118.973 1.00 111.77 ? 672 ARG A O     1 
ATOM 2658 C CB    . ARG A 1 931 ? 151.087 155.748 119.153 1.00 110.59 ? 672 ARG A CB    1 
ATOM 2659 C CG    . ARG A 1 931 ? 151.982 155.116 120.204 1.00 111.20 ? 672 ARG A CG    1 
ATOM 2660 C CD    . ARG A 1 931 ? 152.251 156.079 121.349 1.00 122.14 ? 672 ARG A CD    1 
ATOM 2661 N NE    . ARG A 1 931 ? 153.073 157.208 120.930 1.00 133.30 ? 672 ARG A NE    1 
ATOM 2662 C CZ    . ARG A 1 931 ? 153.304 158.283 121.671 1.00 137.82 ? 672 ARG A CZ    1 
ATOM 2663 N NH1   . ARG A 1 931 ? 152.788 158.411 122.883 1.00 135.22 ? 672 ARG A NH1   1 
ATOM 2664 N NH2   . ARG A 1 931 ? 154.072 159.254 121.185 1.00 141.51 ? 672 ARG A NH2   1 
ATOM 2665 N N     . LYS A 1 932 ? 150.466 152.441 118.499 1.00 106.41 ? 673 LYS A N     1 
ATOM 2666 C CA    . LYS A 1 932 ? 149.772 151.241 118.936 1.00 96.15  ? 673 LYS A CA    1 
ATOM 2667 C C     . LYS A 1 932 ? 149.784 151.132 120.458 1.00 95.39  ? 673 LYS A C     1 
ATOM 2668 O O     . LYS A 1 932 ? 150.622 151.721 121.145 1.00 98.65  ? 673 LYS A O     1 
ATOM 2669 C CB    . LYS A 1 932 ? 150.407 149.998 118.312 1.00 86.46  ? 673 LYS A CB    1 
ATOM 2670 C CG    . LYS A 1 932 ? 150.373 149.985 116.793 1.00 87.18  ? 673 LYS A CG    1 
ATOM 2671 C CD    . LYS A 1 932 ? 148.950 150.123 116.273 1.00 90.62  ? 673 LYS A CD    1 
ATOM 2672 C CE    . LYS A 1 932 ? 148.903 150.066 114.755 1.00 89.45  ? 673 LYS A CE    1 
ATOM 2673 N NZ    . LYS A 1 932 ? 147.531 150.316 114.234 1.00 85.39  ? 673 LYS A NZ    1 
ATOM 2674 N N     . ASN A 1 933 ? 148.829 150.368 120.979 1.00 89.69  ? 674 ASN A N     1 
ATOM 2675 C CA    . ASN A 1 933 ? 148.727 150.168 122.420 1.00 85.22  ? 674 ASN A CA    1 
ATOM 2676 C C     . ASN A 1 933 ? 149.897 149.310 122.894 1.00 76.97  ? 674 ASN A C     1 
ATOM 2677 O O     . ASN A 1 933 ? 150.190 148.278 122.279 1.00 76.23  ? 674 ASN A O     1 
ATOM 2678 C CB    . ASN A 1 933 ? 147.385 149.511 122.761 1.00 85.39  ? 674 ASN A CB    1 
ATOM 2679 C CG    . ASN A 1 933 ? 147.118 149.424 124.261 1.00 80.76  ? 674 ASN A CG    1 
ATOM 2680 O OD1   . ASN A 1 933 ? 147.866 148.801 125.016 1.00 74.17  ? 674 ASN A OD1   1 
ATOM 2681 N ND2   . ASN A 1 933 ? 146.034 150.055 124.694 1.00 87.15  ? 674 ASN A ND2   1 
ATOM 2682 N N     . PRO A 1 934 ? 150.592 149.705 123.965 1.00 76.00  ? 675 PRO A N     1 
ATOM 2683 C CA    . PRO A 1 934 ? 151.765 148.931 124.404 1.00 75.78  ? 675 PRO A CA    1 
ATOM 2684 C C     . PRO A 1 934 ? 151.427 147.552 124.941 1.00 71.17  ? 675 PRO A C     1 
ATOM 2685 O O     . PRO A 1 934 ? 152.266 146.648 124.849 1.00 65.97  ? 675 PRO A O     1 
ATOM 2686 C CB    . PRO A 1 934 ? 152.381 149.820 125.491 1.00 77.55  ? 675 PRO A CB    1 
ATOM 2687 C CG    . PRO A 1 934 ? 151.241 150.636 125.993 1.00 77.02  ? 675 PRO A CG    1 
ATOM 2688 C CD    . PRO A 1 934 ? 150.383 150.904 124.793 1.00 79.14  ? 675 PRO A CD    1 
ATOM 2689 N N     . ARG A 1 935 ? 150.233 147.363 125.509 1.00 72.47  ? 676 ARG A N     1 
ATOM 2690 C CA    . ARG A 1 935 ? 149.881 146.056 126.054 1.00 67.36  ? 676 ARG A CA    1 
ATOM 2691 C C     . ARG A 1 935 ? 149.641 145.033 124.954 1.00 65.85  ? 676 ARG A C     1 
ATOM 2692 O O     . ARG A 1 935 ? 149.916 143.843 125.146 1.00 60.31  ? 676 ARG A O     1 
ATOM 2693 C CB    . ARG A 1 935 ? 148.642 146.167 126.941 1.00 62.64  ? 676 ARG A CB    1 
ATOM 2694 C CG    . ARG A 1 935 ? 148.821 147.049 128.160 1.00 62.32  ? 676 ARG A CG    1 
ATOM 2695 C CD    . ARG A 1 935 ? 147.520 147.179 128.926 1.00 60.98  ? 676 ARG A CD    1 
ATOM 2696 N NE    . ARG A 1 935 ? 147.192 145.951 129.638 1.00 56.15  ? 676 ARG A NE    1 
ATOM 2697 C CZ    . ARG A 1 935 ? 146.305 145.869 130.620 1.00 55.62  ? 676 ARG A CZ    1 
ATOM 2698 N NH1   . ARG A 1 935 ? 145.621 146.926 131.024 1.00 57.35  ? 676 ARG A NH1   1 
ATOM 2699 N NH2   . ARG A 1 935 ? 146.100 144.695 131.211 1.00 56.95  ? 676 ARG A NH2   1 
ATOM 2700 N N     . LEU A 1 936 ? 149.138 145.473 123.803 1.00 67.79  ? 677 LEU A N     1 
ATOM 2701 C CA    . LEU A 1 936 ? 148.795 144.584 122.702 1.00 65.92  ? 677 LEU A CA    1 
ATOM 2702 C C     . LEU A 1 936 ? 149.785 144.663 121.547 1.00 67.98  ? 677 LEU A C     1 
ATOM 2703 O O     . LEU A 1 936 ? 149.534 144.071 120.494 1.00 68.17  ? 677 LEU A O     1 
ATOM 2704 C CB    . LEU A 1 936 ? 147.386 144.901 122.200 1.00 61.81  ? 677 LEU A CB    1 
ATOM 2705 C CG    . LEU A 1 936 ? 146.264 144.756 123.223 1.00 57.80  ? 677 LEU A CG    1 
ATOM 2706 C CD1   . LEU A 1 936 ? 144.931 145.084 122.582 1.00 60.79  ? 677 LEU A CD1   1 
ATOM 2707 C CD2   . LEU A 1 936 ? 146.252 143.352 123.793 1.00 57.48  ? 677 LEU A CD2   1 
ATOM 2708 N N     . SER A 1 937 ? 150.909 145.364 121.727 1.00 67.41  ? 678 SER A N     1 
ATOM 2709 C CA    . SER A 1 937 ? 151.810 145.671 120.620 1.00 68.75  ? 678 SER A CA    1 
ATOM 2710 C C     . SER A 1 937 ? 152.492 144.440 120.039 1.00 66.81  ? 678 SER A C     1 
ATOM 2711 O O     . SER A 1 937 ? 152.908 144.472 118.877 1.00 73.96  ? 678 SER A O     1 
ATOM 2712 C CB    . SER A 1 937 ? 152.871 146.675 121.070 1.00 75.30  ? 678 SER A CB    1 
ATOM 2713 O OG    . SER A 1 937 ? 152.324 147.975 121.196 1.00 80.62  ? 678 SER A OG    1 
ATOM 2714 N N     . LYS A 1 938 ? 152.619 143.364 120.807 1.00 62.64  ? 679 LYS A N     1 
ATOM 2715 C CA    . LYS A 1 938 ? 153.313 142.179 120.326 1.00 65.98  ? 679 LYS A CA    1 
ATOM 2716 C C     . LYS A 1 938 ? 152.402 141.250 119.527 1.00 69.64  ? 679 LYS A C     1 
ATOM 2717 O O     . LYS A 1 938 ? 152.892 140.499 118.674 1.00 73.43  ? 679 LYS A O     1 
ATOM 2718 C CB    . LYS A 1 938 ? 153.952 141.455 121.525 1.00 66.84  ? 679 LYS A CB    1 
ATOM 2719 C CG    . LYS A 1 938 ? 154.637 140.118 121.247 1.00 66.82  ? 679 LYS A CG    1 
ATOM 2720 C CD    . LYS A 1 938 ? 154.753 139.257 122.502 1.00 66.64  ? 679 LYS A CD    1 
ATOM 2721 C CE    . LYS A 1 938 ? 153.496 139.304 123.354 1.00 63.36  ? 679 LYS A CE    1 
ATOM 2722 N NZ    . LYS A 1 938 ? 153.447 138.180 124.325 1.00 63.90  ? 679 LYS A NZ    1 
ATOM 2723 N N     . HIS A 1 939 ? 151.088 141.336 119.722 1.00 67.49  ? 680 HIS A N     1 
ATOM 2724 C CA    . HIS A 1 939 ? 150.146 140.404 119.115 1.00 61.07  ? 680 HIS A CA    1 
ATOM 2725 C C     . HIS A 1 939 ? 149.525 140.893 117.812 1.00 58.97  ? 680 HIS A C     1 
ATOM 2726 O O     . HIS A 1 939 ? 148.689 140.178 117.254 1.00 61.80  ? 680 HIS A O     1 
ATOM 2727 C CB    . HIS A 1 939 ? 149.024 140.067 120.100 1.00 55.87  ? 680 HIS A CB    1 
ATOM 2728 C CG    . HIS A 1 939 ? 149.498 139.422 121.362 1.00 57.53  ? 680 HIS A CG    1 
ATOM 2729 N ND1   . HIS A 1 939 ? 150.097 138.181 121.380 1.00 59.49  ? 680 HIS A ND1   1 
ATOM 2730 C CD2   . HIS A 1 939 ? 149.456 139.838 122.648 1.00 59.21  ? 680 HIS A CD2   1 
ATOM 2731 C CE1   . HIS A 1 939 ? 150.404 137.862 122.623 1.00 62.04  ? 680 HIS A CE1   1 
ATOM 2732 N NE2   . HIS A 1 939 ? 150.029 138.852 123.412 1.00 62.33  ? 680 HIS A NE2   1 
ATOM 2733 N N     . PHE A 1 940 ? 149.895 142.074 117.314 1.00 57.90  ? 681 PHE A N     1 
ATOM 2734 C CA    . PHE A 1 940 ? 149.307 142.558 116.070 1.00 58.88  ? 681 PHE A CA    1 
ATOM 2735 C C     . PHE A 1 940 ? 149.721 141.688 114.885 1.00 61.73  ? 681 PHE A C     1 
ATOM 2736 O O     . PHE A 1 940 ? 150.741 140.994 114.907 1.00 63.73  ? 681 PHE A O     1 
ATOM 2737 C CB    . PHE A 1 940 ? 149.692 144.011 115.793 1.00 61.66  ? 681 PHE A CB    1 
ATOM 2738 C CG    . PHE A 1 940 ? 148.970 145.008 116.648 1.00 60.32  ? 681 PHE A CG    1 
ATOM 2739 C CD1   . PHE A 1 940 ? 147.683 145.403 116.326 1.00 58.38  ? 681 PHE A CD1   1 
ATOM 2740 C CD2   . PHE A 1 940 ? 149.586 145.586 117.740 1.00 65.40  ? 681 PHE A CD2   1 
ATOM 2741 C CE1   . PHE A 1 940 ? 147.010 146.328 117.098 1.00 58.94  ? 681 PHE A CE1   1 
ATOM 2742 C CE2   . PHE A 1 940 ? 148.919 146.514 118.516 1.00 67.55  ? 681 PHE A CE2   1 
ATOM 2743 C CZ    . PHE A 1 940 ? 147.629 146.885 118.193 1.00 63.71  ? 681 PHE A CZ    1 
ATOM 2744 N N     . ILE A 1 941 ? 148.893 141.729 113.841 1.00 61.96  ? 682 ILE A N     1 
ATOM 2745 C CA    . ILE A 1 941 ? 149.085 140.854 112.689 1.00 63.35  ? 682 ILE A CA    1 
ATOM 2746 C C     . ILE A 1 941 ? 150.212 141.363 111.798 1.00 70.31  ? 682 ILE A C     1 
ATOM 2747 O O     . ILE A 1 941 ? 151.120 140.607 111.432 1.00 74.22  ? 682 ILE A O     1 
ATOM 2748 C CB    . ILE A 1 941 ? 147.762 140.714 111.913 1.00 62.44  ? 682 ILE A CB    1 
ATOM 2749 C CG1   . ILE A 1 941 ? 146.814 139.771 112.654 1.00 57.44  ? 682 ILE A CG1   1 
ATOM 2750 C CG2   . ILE A 1 941 ? 148.007 140.214 110.497 1.00 64.87  ? 682 ILE A CG2   1 
ATOM 2751 C CD1   . ILE A 1 941 ? 147.303 138.345 112.717 1.00 54.23  ? 682 ILE A CD1   1 
ATOM 2752 N N     . GLU A 1 942 ? 150.183 142.646 111.447 1.00 71.14  ? 683 GLU A N     1 
ATOM 2753 C CA    . GLU A 1 942 ? 151.173 143.204 110.529 1.00 73.37  ? 683 GLU A CA    1 
ATOM 2754 C C     . GLU A 1 942 ? 152.528 143.394 111.208 1.00 76.24  ? 683 GLU A C     1 
ATOM 2755 O O     . GLU A 1 942 ? 152.629 143.419 112.434 1.00 74.15  ? 683 GLU A O     1 
ATOM 2756 C CB    . GLU A 1 942 ? 150.681 144.538 109.950 1.00 70.82  ? 683 GLU A CB    1 
ATOM 2757 C CG    . GLU A 1 942 ? 151.104 145.786 110.725 1.00 72.46  ? 683 GLU A CG    1 
ATOM 2758 C CD    . GLU A 1 942 ? 150.497 145.874 112.114 1.00 73.80  ? 683 GLU A CD    1 
ATOM 2759 O OE1   . GLU A 1 942 ? 149.435 145.262 112.350 1.00 70.62  ? 683 GLU A OE1   1 
ATOM 2760 O OE2   . GLU A 1 942 ? 151.091 146.558 112.973 1.00 77.04  ? 683 GLU A OE2   1 
ATOM 2761 O OXT   . GLU A 1 942 ? 153.555 143.524 110.543 1.00 76.42  ? 683 GLU A OXT   1 
ATOM 2762 P P     . A   B 2 10  ? 108.602 152.031 144.062 1.00 206.71 ? 10  A   B P     1 
ATOM 2763 O OP1   . A   B 2 10  ? 108.203 153.395 144.490 1.00 206.40 ? 10  A   B OP1   1 
ATOM 2764 O OP2   . A   B 2 10  ? 108.187 150.861 144.877 1.00 199.83 ? 10  A   B OP2   1 
ATOM 2765 O "O5'" . A   B 2 10  ? 110.190 152.005 143.939 1.00 202.85 ? 10  A   B "O5'" 1 
ATOM 2766 C "C5'" . A   B 2 10  ? 111.002 151.940 145.105 1.00 197.07 ? 10  A   B "C5'" 1 
ATOM 2767 C "C4'" . A   B 2 10  ? 112.424 151.545 144.790 1.00 194.07 ? 10  A   B "C4'" 1 
ATOM 2768 O "O4'" . A   B 2 10  ? 113.047 151.072 146.013 1.00 192.17 ? 10  A   B "O4'" 1 
ATOM 2769 C "C3'" . A   B 2 10  ? 112.579 150.416 143.776 1.00 193.54 ? 10  A   B "C3'" 1 
ATOM 2770 O "O3'" . A   B 2 10  ? 113.816 150.581 143.082 1.00 193.43 ? 10  A   B "O3'" 1 
ATOM 2771 C "C2'" . A   B 2 10  ? 112.656 149.183 144.668 1.00 189.10 ? 10  A   B "C2'" 1 
ATOM 2772 O "O2'" . A   B 2 10  ? 113.294 148.068 144.081 1.00 186.63 ? 10  A   B "O2'" 1 
ATOM 2773 C "C1'" . A   B 2 10  ? 113.437 149.718 145.866 1.00 188.62 ? 10  A   B "C1'" 1 
ATOM 2774 N N9    . A   B 2 10  ? 113.120 149.030 147.118 1.00 187.46 ? 10  A   B N9    1 
ATOM 2775 C C8    . A   B 2 10  ? 112.386 147.881 147.277 1.00 185.26 ? 10  A   B C8    1 
ATOM 2776 N N7    . A   B 2 10  ? 112.268 147.500 148.525 1.00 183.33 ? 10  A   B N7    1 
ATOM 2777 C C5    . A   B 2 10  ? 112.967 148.468 149.234 1.00 184.06 ? 10  A   B C5    1 
ATOM 2778 C C6    . A   B 2 10  ? 113.224 148.642 150.605 1.00 182.05 ? 10  A   B C6    1 
ATOM 2779 N N6    . A   B 2 10  ? 112.780 147.811 151.551 1.00 181.61 ? 10  A   B N6    1 
ATOM 2780 N N1    . A   B 2 10  ? 113.960 149.714 150.980 1.00 179.74 ? 10  A   B N1    1 
ATOM 2781 C C2    . A   B 2 10  ? 114.408 150.551 150.035 1.00 181.44 ? 10  A   B C2    1 
ATOM 2782 N N3    . A   B 2 10  ? 114.235 150.491 148.717 1.00 184.72 ? 10  A   B N3    1 
ATOM 2783 C C4    . A   B 2 10  ? 113.500 149.416 148.379 1.00 185.92 ? 10  A   B C4    1 
ATOM 2784 P P     . G   B 2 11  ? 113.989 150.045 141.576 1.00 193.13 ? 11  G   B P     1 
ATOM 2785 O OP1   . G   B 2 11  ? 114.068 151.227 140.681 1.00 188.47 ? 11  G   B OP1   1 
ATOM 2786 O OP2   . G   B 2 11  ? 112.960 149.006 141.321 1.00 191.39 ? 11  G   B OP2   1 
ATOM 2787 O "O5'" . G   B 2 11  ? 115.422 149.346 141.586 1.00 180.89 ? 11  G   B "O5'" 1 
ATOM 2788 C "C5'" . G   B 2 11  ? 116.609 150.122 141.502 1.00 173.06 ? 11  G   B "C5'" 1 
ATOM 2789 C "C4'" . G   B 2 11  ? 117.683 149.605 142.429 1.00 170.39 ? 11  G   B "C4'" 1 
ATOM 2790 O "O4'" . G   B 2 11  ? 117.099 149.246 143.706 1.00 175.05 ? 11  G   B "O4'" 1 
ATOM 2791 C "C3'" . G   B 2 11  ? 118.411 148.348 141.978 1.00 162.64 ? 11  G   B "C3'" 1 
ATOM 2792 O "O3'" . G   B 2 11  ? 119.466 148.643 141.077 1.00 161.37 ? 11  G   B "O3'" 1 
ATOM 2793 C "C2'" . G   B 2 11  ? 118.892 147.740 143.292 1.00 160.78 ? 11  G   B "C2'" 1 
ATOM 2794 O "O2'" . G   B 2 11  ? 120.075 148.388 143.729 1.00 155.35 ? 11  G   B "O2'" 1 
ATOM 2795 C "C1'" . G   B 2 11  ? 117.770 148.131 144.252 1.00 167.91 ? 11  G   B "C1'" 1 
ATOM 2796 N N9    . G   B 2 11  ? 116.779 147.063 144.487 1.00 172.56 ? 11  G   B N9    1 
ATOM 2797 C C8    . G   B 2 11  ? 116.198 146.181 143.606 1.00 170.43 ? 11  G   B C8    1 
ATOM 2798 N N7    . G   B 2 11  ? 115.326 145.392 144.178 1.00 171.59 ? 11  G   B N7    1 
ATOM 2799 C C5    . G   B 2 11  ? 115.321 145.787 145.510 1.00 177.36 ? 11  G   B C5    1 
ATOM 2800 C C6    . G   B 2 11  ? 114.584 145.304 146.624 1.00 179.52 ? 11  G   B C6    1 
ATOM 2801 O O6    . G   B 2 11  ? 113.743 144.398 146.659 1.00 179.13 ? 11  G   B O6    1 
ATOM 2802 N N1    . G   B 2 11  ? 114.898 146.000 147.788 1.00 180.80 ? 11  G   B N1    1 
ATOM 2803 C C2    . G   B 2 11  ? 115.807 147.027 147.876 1.00 179.44 ? 11  G   B C2    1 
ATOM 2804 N N2    . G   B 2 11  ? 115.982 147.576 149.087 1.00 181.00 ? 11  G   B N2    1 
ATOM 2805 N N3    . G   B 2 11  ? 116.500 147.481 146.848 1.00 175.89 ? 11  G   B N3    1 
ATOM 2806 C C4    . G   B 2 11  ? 116.207 146.820 145.709 1.00 174.89 ? 11  G   B C4    1 
ATOM 2807 P P     . A   B 2 12  ? 120.116 147.498 140.155 1.00 158.96 ? 12  A   B P     1 
ATOM 2808 O OP1   . A   B 2 12  ? 120.236 148.035 138.776 1.00 157.36 ? 12  A   B OP1   1 
ATOM 2809 O OP2   . A   B 2 12  ? 119.372 146.233 140.382 1.00 151.92 ? 12  A   B OP2   1 
ATOM 2810 O "O5'" . A   B 2 12  ? 121.588 147.316 140.739 1.00 145.62 ? 12  A   B "O5'" 1 
ATOM 2811 C "C5'" . A   B 2 12  ? 122.308 148.405 141.305 1.00 137.92 ? 12  A   B "C5'" 1 
ATOM 2812 C "C4'" . A   B 2 12  ? 123.110 147.946 142.497 1.00 128.94 ? 12  A   B "C4'" 1 
ATOM 2813 O "O4'" . A   B 2 12  ? 122.193 147.540 143.547 1.00 134.88 ? 12  A   B "O4'" 1 
ATOM 2814 C "C3'" . A   B 2 12  ? 123.983 146.724 142.242 1.00 117.15 ? 12  A   B "C3'" 1 
ATOM 2815 O "O3'" . A   B 2 12  ? 125.275 147.066 141.771 1.00 108.93 ? 12  A   B "O3'" 1 
ATOM 2816 C "C2'" . A   B 2 12  ? 123.992 146.002 143.584 1.00 113.36 ? 12  A   B "C2'" 1 
ATOM 2817 O "O2'" . A   B 2 12  ? 124.949 146.584 144.457 1.00 107.01 ? 12  A   B "O2'" 1 
ATOM 2818 C "C1'" . A   B 2 12  ? 122.601 146.323 144.121 1.00 125.42 ? 12  A   B "C1'" 1 
ATOM 2819 N N9    . A   B 2 12  ? 121.574 145.311 143.784 1.00 136.12 ? 12  A   B N9    1 
ATOM 2820 C C8    . A   B 2 12  ? 121.337 144.642 142.603 1.00 135.19 ? 12  A   B C8    1 
ATOM 2821 N N7    . A   B 2 12  ? 120.305 143.837 142.633 1.00 143.48 ? 12  A   B N7    1 
ATOM 2822 C C5    . A   B 2 12  ? 119.809 143.993 143.917 1.00 148.14 ? 12  A   B C5    1 
ATOM 2823 C C6    . A   B 2 12  ? 118.718 143.413 144.586 1.00 152.48 ? 12  A   B C6    1 
ATOM 2824 N N6    . A   B 2 12  ? 117.896 142.522 144.027 1.00 150.99 ? 12  A   B N6    1 
ATOM 2825 N N1    . A   B 2 12  ? 118.496 143.786 145.867 1.00 154.36 ? 12  A   B N1    1 
ATOM 2826 C C2    . A   B 2 12  ? 119.317 144.681 146.431 1.00 150.78 ? 12  A   B C2    1 
ATOM 2827 N N3    . A   B 2 12  ? 120.375 145.293 145.903 1.00 144.46 ? 12  A   B N3    1 
ATOM 2828 C C4    . A   B 2 12  ? 120.570 144.902 144.631 1.00 143.83 ? 12  A   B C4    1 
ATOM 2829 P P     . U   B 2 13  ? 125.867 146.370 140.451 1.00 107.59 ? 13  U   B P     1 
ATOM 2830 O OP1   . U   B 2 13  ? 125.873 147.380 139.364 1.00 113.07 ? 13  U   B OP1   1 
ATOM 2831 O OP2   . U   B 2 13  ? 125.157 145.082 140.251 1.00 102.14 ? 13  U   B OP2   1 
ATOM 2832 O "O5'" . U   B 2 13  ? 127.378 146.049 140.836 1.00 88.31  ? 13  U   B "O5'" 1 
ATOM 2833 C "C5'" . U   B 2 13  ? 127.785 144.724 141.142 1.00 79.22  ? 13  U   B "C5'" 1 
ATOM 2834 C "C4'" . U   B 2 13  ? 128.366 144.632 142.529 1.00 77.28  ? 13  U   B "C4'" 1 
ATOM 2835 O "O4'" . U   B 2 13  ? 127.369 145.032 143.500 1.00 87.77  ? 13  U   B "O4'" 1 
ATOM 2836 C "C3'" . U   B 2 13  ? 128.787 143.244 142.980 1.00 64.19  ? 13  U   B "C3'" 1 
ATOM 2837 O "O3'" . U   B 2 13  ? 130.063 142.880 142.494 1.00 57.99  ? 13  U   B "O3'" 1 
ATOM 2838 C "C2'" . U   B 2 13  ? 128.714 143.342 144.501 1.00 67.95  ? 13  U   B "C2'" 1 
ATOM 2839 O "O2'" . U   B 2 13  ? 129.889 143.947 145.019 1.00 66.04  ? 13  U   B "O2'" 1 
ATOM 2840 C "C1'" . U   B 2 13  ? 127.546 144.313 144.700 1.00 81.22  ? 13  U   B "C1'" 1 
ATOM 2841 N N1    . U   B 2 13  ? 126.271 143.644 145.062 1.00 80.66  ? 13  U   B N1    1 
ATOM 2842 C C2    . U   B 2 13  ? 125.834 143.849 146.353 1.00 79.41  ? 13  U   B C2    1 
ATOM 2843 O O2    . U   B 2 13  ? 126.451 144.531 147.150 1.00 79.74  ? 13  U   B O2    1 
ATOM 2844 N N3    . U   B 2 13  ? 124.651 143.240 146.680 1.00 83.23  ? 13  U   B N3    1 
ATOM 2845 C C4    . U   B 2 13  ? 123.871 142.456 145.861 1.00 87.02  ? 13  U   B C4    1 
ATOM 2846 O O4    . U   B 2 13  ? 122.831 141.971 146.304 1.00 96.17  ? 13  U   B O4    1 
ATOM 2847 C C5    . U   B 2 13  ? 124.384 142.283 144.538 1.00 82.83  ? 13  U   B C5    1 
ATOM 2848 C C6    . U   B 2 13  ? 125.535 142.867 144.195 1.00 81.81  ? 13  U   B C6    1 
ATOM 2849 P P     . G   B 2 14  ? 130.200 141.723 141.393 1.00 52.96  ? 14  G   B P     1 
ATOM 2850 O OP1   . G   B 2 14  ? 131.202 142.138 140.382 1.00 54.34  ? 14  G   B OP1   1 
ATOM 2851 O OP2   . G   B 2 14  ? 128.830 141.360 140.963 1.00 55.16  ? 14  G   B OP2   1 
ATOM 2852 O "O5'" . G   B 2 14  ? 130.804 140.501 142.208 1.00 47.06  ? 14  G   B "O5'" 1 
ATOM 2853 C "C5'" . G   B 2 14  ? 131.596 140.723 143.363 1.00 45.63  ? 14  G   B "C5'" 1 
ATOM 2854 C "C4'" . G   B 2 14  ? 131.334 139.674 144.409 1.00 42.57  ? 14  G   B "C4'" 1 
ATOM 2855 O "O4'" . G   B 2 14  ? 130.114 139.983 145.118 1.00 42.27  ? 14  G   B "O4'" 1 
ATOM 2856 C "C3'" . G   B 2 14  ? 131.126 138.267 143.880 1.00 37.81  ? 14  G   B "C3'" 1 
ATOM 2857 O "O3'" . G   B 2 14  ? 132.361 137.606 143.680 1.00 35.78  ? 14  G   B "O3'" 1 
ATOM 2858 C "C2'" . G   B 2 14  ? 130.261 137.611 144.950 1.00 35.83  ? 14  G   B "C2'" 1 
ATOM 2859 O "O2'" . G   B 2 14  ? 131.071 137.093 145.990 1.00 35.83  ? 14  G   B "O2'" 1 
ATOM 2860 C "C1'" . G   B 2 14  ? 129.460 138.796 145.498 1.00 41.23  ? 14  G   B "C1'" 1 
ATOM 2861 N N9    . G   B 2 14  ? 128.070 138.850 145.008 1.00 45.74  ? 14  G   B N9    1 
ATOM 2862 C C8    . G   B 2 14  ? 127.607 139.524 143.907 1.00 51.30  ? 14  G   B C8    1 
ATOM 2863 N N7    . G   B 2 14  ? 126.321 139.405 143.733 1.00 51.64  ? 14  G   B N7    1 
ATOM 2864 C C5    . G   B 2 14  ? 125.908 138.616 144.794 1.00 50.29  ? 14  G   B C5    1 
ATOM 2865 C C6    . G   B 2 14  ? 124.617 138.145 145.134 1.00 57.50  ? 14  G   B C6    1 
ATOM 2866 O O6    . G   B 2 14  ? 123.547 138.349 144.551 1.00 64.56  ? 14  G   B O6    1 
ATOM 2867 N N1    . G   B 2 14  ? 124.642 137.372 146.288 1.00 51.94  ? 14  G   B N1    1 
ATOM 2868 C C2    . G   B 2 14  ? 125.766 137.086 147.018 1.00 49.04  ? 14  G   B C2    1 
ATOM 2869 N N2    . G   B 2 14  ? 125.586 136.318 148.101 1.00 49.22  ? 14  G   B N2    1 
ATOM 2870 N N3    . G   B 2 14  ? 126.976 137.514 146.708 1.00 47.36  ? 14  G   B N3    1 
ATOM 2871 C C4    . G   B 2 14  ? 126.973 138.268 145.592 1.00 45.57  ? 14  G   B C4    1 
ATOM 2872 P P     . A   B 2 15  ? 132.558 136.575 142.470 1.00 37.52  ? 15  A   B P     1 
ATOM 2873 O OP1   . A   B 2 15  ? 134.003 136.518 142.152 1.00 35.15  ? 15  A   B OP1   1 
ATOM 2874 O OP2   . A   B 2 15  ? 131.580 136.903 141.407 1.00 40.04  ? 15  A   B OP2   1 
ATOM 2875 O "O5'" . A   B 2 15  ? 132.182 135.173 143.114 1.00 34.89  ? 15  A   B "O5'" 1 
ATOM 2876 C "C5'" . A   B 2 15  ? 132.857 134.705 144.269 1.00 29.69  ? 15  A   B "C5'" 1 
ATOM 2877 C "C4'" . A   B 2 15  ? 132.316 133.372 144.708 1.00 29.37  ? 15  A   B "C4'" 1 
ATOM 2878 O "O4'" . A   B 2 15  ? 130.922 133.513 145.062 1.00 31.19  ? 15  A   B "O4'" 1 
ATOM 2879 C "C3'" . A   B 2 15  ? 132.325 132.285 143.649 1.00 30.69  ? 15  A   B "C3'" 1 
ATOM 2880 O "O3'" . A   B 2 15  ? 133.577 131.632 143.569 1.00 28.25  ? 15  A   B "O3'" 1 
ATOM 2881 C "C2'" . A   B 2 15  ? 131.193 131.364 144.082 1.00 28.96  ? 15  A   B "C2'" 1 
ATOM 2882 O "O2'" . A   B 2 15  ? 131.640 130.454 145.072 1.00 34.89  ? 15  A   B "O2'" 1 
ATOM 2883 C "C1'" . A   B 2 15  ? 130.218 132.341 144.732 1.00 29.37  ? 15  A   B "C1'" 1 
ATOM 2884 N N9    . A   B 2 15  ? 129.075 132.699 143.874 1.00 34.01  ? 15  A   B N9    1 
ATOM 2885 C C8    . A   B 2 15  ? 128.843 133.892 143.244 1.00 39.49  ? 15  A   B C8    1 
ATOM 2886 N N7    . A   B 2 15  ? 127.718 133.927 142.573 1.00 42.58  ? 15  A   B N7    1 
ATOM 2887 C C5    . A   B 2 15  ? 127.169 132.673 142.788 1.00 43.59  ? 15  A   B C5    1 
ATOM 2888 C C6    . A   B 2 15  ? 125.978 132.071 142.352 1.00 44.59  ? 15  A   B C6    1 
ATOM 2889 N N6    . A   B 2 15  ? 125.086 132.681 141.570 1.00 46.32  ? 15  A   B N6    1 
ATOM 2890 N N1    . A   B 2 15  ? 125.729 130.805 142.749 1.00 46.42  ? 15  A   B N1    1 
ATOM 2891 C C2    . A   B 2 15  ? 126.620 130.188 143.535 1.00 48.11  ? 15  A   B C2    1 
ATOM 2892 N N3    . A   B 2 15  ? 127.774 130.649 144.009 1.00 46.59  ? 15  A   B N3    1 
ATOM 2893 C C4    . A   B 2 15  ? 127.991 131.908 143.592 1.00 42.29  ? 15  A   B C4    1 
ATOM 2894 P P     . G   B 2 16  ? 134.104 131.062 142.167 1.00 38.91  ? 16  G   B P     1 
ATOM 2895 O OP1   . G   B 2 16  ? 135.501 130.615 142.368 1.00 32.68  ? 16  G   B OP1   1 
ATOM 2896 O OP2   . G   B 2 16  ? 133.779 132.047 141.109 1.00 34.21  ? 16  G   B OP2   1 
ATOM 2897 O "O5'" . G   B 2 16  ? 133.217 129.765 141.926 1.00 38.77  ? 16  G   B "O5'" 1 
ATOM 2898 C "C5'" . G   B 2 16  ? 133.311 128.658 142.805 1.00 35.41  ? 16  G   B "C5'" 1 
ATOM 2899 C "C4'" . G   B 2 16  ? 132.174 127.693 142.603 1.00 36.75  ? 16  G   B "C4'" 1 
ATOM 2900 O "O4'" . G   B 2 16  ? 130.913 128.373 142.766 1.00 36.34  ? 16  G   B "O4'" 1 
ATOM 2901 C "C3'" . G   B 2 16  ? 132.077 127.052 141.232 1.00 37.40  ? 16  G   B "C3'" 1 
ATOM 2902 O "O3'" . G   B 2 16  ? 132.939 125.935 141.136 1.00 39.70  ? 16  G   B "O3'" 1 
ATOM 2903 C "C2'" . G   B 2 16  ? 130.604 126.668 141.137 1.00 37.12  ? 16  G   B "C2'" 1 
ATOM 2904 O "O2'" . G   B 2 16  ? 130.379 125.410 141.752 1.00 34.77  ? 16  G   B "O2'" 1 
ATOM 2905 C "C1'" . G   B 2 16  ? 129.928 127.743 141.988 1.00 37.06  ? 16  G   B "C1'" 1 
ATOM 2906 N N9    . G   B 2 16  ? 129.187 128.758 141.219 1.00 39.95  ? 16  G   B N9    1 
ATOM 2907 C C8    . G   B 2 16  ? 129.584 130.023 140.873 1.00 41.29  ? 16  G   B C8    1 
ATOM 2908 N N7    . G   B 2 16  ? 128.666 130.687 140.227 1.00 40.71  ? 16  G   B N7    1 
ATOM 2909 C C5    . G   B 2 16  ? 127.592 129.813 140.158 1.00 42.75  ? 16  G   B C5    1 
ATOM 2910 C C6    . G   B 2 16  ? 126.310 129.965 139.573 1.00 49.69  ? 16  G   B C6    1 
ATOM 2911 O O6    . G   B 2 16  ? 125.842 130.945 138.983 1.00 57.47  ? 16  G   B O6    1 
ATOM 2912 N N1    . G   B 2 16  ? 125.534 128.824 139.736 1.00 50.72  ? 16  G   B N1    1 
ATOM 2913 C C2    . G   B 2 16  ? 125.940 127.679 140.375 1.00 48.99  ? 16  G   B C2    1 
ATOM 2914 N N2    . G   B 2 16  ? 125.050 126.679 140.431 1.00 50.68  ? 16  G   B N2    1 
ATOM 2915 N N3    . G   B 2 16  ? 127.132 127.524 140.920 1.00 45.89  ? 16  G   B N3    1 
ATOM 2916 C C4    . G   B 2 16  ? 127.898 128.622 140.773 1.00 42.39  ? 16  G   B C4    1 
ATOM 2917 P P     . A   B 2 17  ? 133.686 125.558 139.767 1.00 43.41  ? 17  A   B P     1 
ATOM 2918 O OP1   . A   B 2 17  ? 133.802 124.080 139.783 1.00 42.16  ? 17  A   B OP1   1 
ATOM 2919 O OP2   . A   B 2 17  ? 134.890 126.407 139.608 1.00 35.78  ? 17  A   B OP2   1 
ATOM 2920 O "O5'" . A   B 2 17  ? 132.654 125.943 138.623 1.00 43.60  ? 17  A   B "O5'" 1 
ATOM 2921 C "C5'" . A   B 2 17  ? 132.450 125.080 137.516 1.00 44.27  ? 17  A   B "C5'" 1 
ATOM 2922 C "C4'" . A   B 2 17  ? 131.187 124.280 137.687 1.00 42.24  ? 17  A   B "C4'" 1 
ATOM 2923 O "O4'" . A   B 2 17  ? 130.206 125.086 138.379 1.00 41.61  ? 17  A   B "O4'" 1 
ATOM 2924 C "C3'" . A   B 2 17  ? 130.490 123.838 136.410 1.00 42.77  ? 17  A   B "C3'" 1 
ATOM 2925 O "O3'" . A   B 2 17  ? 131.029 122.620 135.921 1.00 43.41  ? 17  A   B "O3'" 1 
ATOM 2926 C "C2'" . A   B 2 17  ? 129.041 123.704 136.851 1.00 42.49  ? 17  A   B "C2'" 1 
ATOM 2927 O "O2'" . A   B 2 17  ? 128.870 122.465 137.511 1.00 47.37  ? 17  A   B "O2'" 1 
ATOM 2928 C "C1'" . A   B 2 17  ? 128.919 124.813 137.891 1.00 40.81  ? 17  A   B "C1'" 1 
ATOM 2929 N N9    . A   B 2 17  ? 128.365 126.068 137.357 1.00 39.98  ? 17  A   B N9    1 
ATOM 2930 C C8    . A   B 2 17  ? 129.053 127.242 137.211 1.00 44.14  ? 17  A   B C8    1 
ATOM 2931 N N7    . A   B 2 17  ? 128.338 128.228 136.737 1.00 47.99  ? 17  A   B N7    1 
ATOM 2932 C C5    . A   B 2 17  ? 127.084 127.667 136.570 1.00 47.24  ? 17  A   B C5    1 
ATOM 2933 C C6    . A   B 2 17  ? 125.875 128.200 136.095 1.00 50.85  ? 17  A   B C6    1 
ATOM 2934 N N6    . A   B 2 17  ? 125.733 129.462 135.690 1.00 48.62  ? 17  A   B N6    1 
ATOM 2935 N N1    . A   B 2 17  ? 124.802 127.383 136.048 1.00 56.80  ? 17  A   B N1    1 
ATOM 2936 C C2    . A   B 2 17  ? 124.944 126.117 136.455 1.00 54.25  ? 17  A   B C2    1 
ATOM 2937 N N3    . A   B 2 17  ? 126.030 125.501 136.920 1.00 51.87  ? 17  A   B N3    1 
ATOM 2938 C C4    . A   B 2 17  ? 127.080 126.339 136.955 1.00 45.17  ? 17  A   B C4    1 
ATOM 2939 P P     . C   B 2 18  ? 130.953 122.224 134.365 1.00 46.45  ? 18  C   B P     1 
ATOM 2940 O OP1   . C   B 2 18  ? 131.535 120.868 134.231 1.00 43.53  ? 18  C   B OP1   1 
ATOM 2941 O OP2   . C   B 2 18  ? 131.502 123.329 133.553 1.00 52.69  ? 18  C   B OP2   1 
ATOM 2942 O "O5'" . C   B 2 18  ? 129.398 122.096 134.060 1.00 41.05  ? 18  C   B "O5'" 1 
ATOM 2943 C "C5'" . C   B 2 18  ? 128.659 120.966 134.496 1.00 42.43  ? 18  C   B "C5'" 1 
ATOM 2944 C "C4'" . C   B 2 18  ? 127.204 121.101 134.131 1.00 46.57  ? 18  C   B "C4'" 1 
ATOM 2945 O "O4'" . C   B 2 18  ? 126.683 122.346 134.641 1.00 44.55  ? 18  C   B "O4'" 1 
ATOM 2946 C "C3'" . C   B 2 18  ? 126.907 121.142 132.645 1.00 45.22  ? 18  C   B "C3'" 1 
ATOM 2947 O "O3'" . C   B 2 18  ? 126.812 119.833 132.112 1.00 44.04  ? 18  C   B "O3'" 1 
ATOM 2948 C "C2'" . C   B 2 18  ? 125.596 121.919 132.566 1.00 43.49  ? 18  C   B "C2'" 1 
ATOM 2949 O "O2'" . C   B 2 18  ? 124.490 121.052 132.743 1.00 48.29  ? 18  C   B "O2'" 1 
ATOM 2950 C "C1'" . C   B 2 18  ? 125.680 122.837 133.787 1.00 40.25  ? 18  C   B "C1'" 1 
ATOM 2951 N N1    . C   B 2 18  ? 125.969 124.256 133.479 1.00 40.30  ? 18  C   B N1    1 
ATOM 2952 C C2    . C   B 2 18  ? 124.971 125.077 132.954 1.00 46.90  ? 18  C   B C2    1 
ATOM 2953 O O2    . C   B 2 18  ? 123.857 124.606 132.701 1.00 53.65  ? 18  C   B O2    1 
ATOM 2954 N N3    . C   B 2 18  ? 125.240 126.377 132.710 1.00 49.10  ? 18  C   B N3    1 
ATOM 2955 C C4    . C   B 2 18  ? 126.442 126.871 132.990 1.00 46.86  ? 18  C   B C4    1 
ATOM 2956 N N4    . C   B 2 18  ? 126.659 128.161 132.733 1.00 47.82  ? 18  C   B N4    1 
ATOM 2957 C C5    . C   B 2 18  ? 127.472 126.066 133.544 1.00 44.42  ? 18  C   B C5    1 
ATOM 2958 C C6    . C   B 2 18  ? 127.190 124.782 133.778 1.00 44.18  ? 18  C   B C6    1 
ATOM 2959 P P     . G   B 2 19  ? 127.235 119.520 130.599 1.00 41.79  ? 19  G   B P     1 
ATOM 2960 O OP1   . G   B 2 19  ? 126.940 118.092 130.345 1.00 53.56  ? 19  G   B OP1   1 
ATOM 2961 O OP2   . G   B 2 19  ? 128.587 120.059 130.339 1.00 35.19  ? 19  G   B OP2   1 
ATOM 2962 O "O5'" . G   B 2 19  ? 126.190 120.347 129.743 1.00 46.99  ? 19  G   B "O5'" 1 
ATOM 2963 C "C5'" . G   B 2 19  ? 126.622 121.276 128.769 1.00 45.30  ? 19  G   B "C5'" 1 
ATOM 2964 C "C4'" . G   B 2 19  ? 125.498 122.199 128.398 1.00 46.02  ? 19  G   B "C4'" 1 
ATOM 2965 O "O4'" . G   B 2 19  ? 125.333 123.206 129.425 1.00 44.86  ? 19  G   B "O4'" 1 
ATOM 2966 C "C3'" . G   B 2 19  ? 125.688 122.999 127.127 1.00 50.28  ? 19  G   B "C3'" 1 
ATOM 2967 O "O3'" . G   B 2 19  ? 125.396 122.239 125.967 1.00 54.97  ? 19  G   B "O3'" 1 
ATOM 2968 C "C2'" . G   B 2 19  ? 124.756 124.181 127.346 1.00 49.81  ? 19  G   B "C2'" 1 
ATOM 2969 O "O2'" . G   B 2 19  ? 123.407 123.808 127.114 1.00 55.70  ? 19  G   B "O2'" 1 
ATOM 2970 C "C1'" . G   B 2 19  ? 124.931 124.425 128.843 1.00 47.59  ? 19  G   B "C1'" 1 
ATOM 2971 N N9    . G   B 2 19  ? 125.967 125.434 129.119 1.00 49.20  ? 19  G   B N9    1 
ATOM 2972 C C8    . G   B 2 19  ? 127.201 125.220 129.680 1.00 51.50  ? 19  G   B C8    1 
ATOM 2973 N N7    . G   B 2 19  ? 127.904 126.312 129.798 1.00 57.62  ? 19  G   B N7    1 
ATOM 2974 C C5    . G   B 2 19  ? 127.084 127.306 129.285 1.00 54.97  ? 19  G   B C5    1 
ATOM 2975 C C6    . G   B 2 19  ? 127.308 128.698 129.144 1.00 54.82  ? 19  G   B C6    1 
ATOM 2976 O O6    . G   B 2 19  ? 128.307 129.349 129.467 1.00 53.89  ? 19  G   B O6    1 
ATOM 2977 N N1    . G   B 2 19  ? 126.217 129.341 128.573 1.00 54.42  ? 19  G   B N1    1 
ATOM 2978 C C2    . G   B 2 19  ? 125.059 128.719 128.183 1.00 56.07  ? 19  G   B C2    1 
ATOM 2979 N N2    . G   B 2 19  ? 124.116 129.506 127.649 1.00 57.57  ? 19  G   B N2    1 
ATOM 2980 N N3    . G   B 2 19  ? 124.838 127.422 128.307 1.00 56.38  ? 19  G   B N3    1 
ATOM 2981 C C4    . G   B 2 19  ? 125.886 126.780 128.861 1.00 53.24  ? 19  G   B C4    1 
ATOM 2982 P P     . C   B 2 20  ? 126.347 122.328 124.678 1.00 50.56  ? 20  C   B P     1 
ATOM 2983 O OP1   . C   B 2 20  ? 126.022 121.180 123.797 1.00 60.33  ? 20  C   B OP1   1 
ATOM 2984 O OP2   . C   B 2 20  ? 127.748 122.531 125.121 1.00 47.35  ? 20  C   B OP2   1 
ATOM 2985 O "O5'" . C   B 2 20  ? 125.851 123.651 123.953 1.00 47.21  ? 20  C   B "O5'" 1 
ATOM 2986 C "C5'" . C   B 2 20  ? 124.480 123.818 123.639 1.00 49.66  ? 20  C   B "C5'" 1 
ATOM 2987 C "C4'" . C   B 2 20  ? 124.138 125.264 123.408 1.00 50.00  ? 20  C   B "C4'" 1 
ATOM 2988 O "O4'" . C   B 2 20  ? 124.355 126.028 124.626 1.00 49.77  ? 20  C   B "O4'" 1 
ATOM 2989 C "C3'" . C   B 2 20  ? 124.987 125.983 122.379 1.00 52.30  ? 20  C   B "C3'" 1 
ATOM 2990 O "O3'" . C   B 2 20  ? 124.616 125.699 121.043 1.00 53.37  ? 20  C   B "O3'" 1 
ATOM 2991 C "C2'" . C   B 2 20  ? 124.807 127.437 122.778 1.00 53.42  ? 20  C   B "C2'" 1 
ATOM 2992 O "O2'" . C   B 2 20  ? 123.532 127.910 122.374 1.00 60.58  ? 20  C   B "O2'" 1 
ATOM 2993 C "C1'" . C   B 2 20  ? 124.811 127.326 124.302 1.00 50.57  ? 20  C   B "C1'" 1 
ATOM 2994 N N1    . C   B 2 20  ? 126.171 127.507 124.872 1.00 50.94  ? 20  C   B N1    1 
ATOM 2995 C C2    . C   B 2 20  ? 126.805 128.761 124.865 1.00 54.63  ? 20  C   B C2    1 
ATOM 2996 O O2    . C   B 2 20  ? 126.251 129.759 124.378 1.00 55.19  ? 20  C   B O2    1 
ATOM 2997 N N3    . C   B 2 20  ? 128.046 128.873 125.387 1.00 57.70  ? 20  C   B N3    1 
ATOM 2998 C C4    . C   B 2 20  ? 128.661 127.817 125.915 1.00 56.94  ? 20  C   B C4    1 
ATOM 2999 N N4    . C   B 2 20  ? 129.882 127.986 126.422 1.00 60.46  ? 20  C   B N4    1 
ATOM 3000 C C5    . C   B 2 20  ? 128.049 126.538 125.948 1.00 54.88  ? 20  C   B C5    1 
ATOM 3001 C C6    . C   B 2 20  ? 126.824 126.440 125.423 1.00 53.60  ? 20  C   B C6    1 
ATOM 3002 P P     . G   B 2 21  ? 125.750 125.508 119.921 1.00 50.26  ? 21  G   B P     1 
ATOM 3003 O OP1   . G   B 2 21  ? 125.079 125.130 118.655 1.00 62.63  ? 21  G   B OP1   1 
ATOM 3004 O OP2   . G   B 2 21  ? 126.821 124.640 120.465 1.00 51.18  ? 21  G   B OP2   1 
ATOM 3005 O "O5'" . G   B 2 21  ? 126.349 126.970 119.736 1.00 48.85  ? 21  G   B "O5'" 1 
ATOM 3006 C "C5'" . G   B 2 21  ? 125.544 128.017 119.220 1.00 53.89  ? 21  G   B "C5'" 1 
ATOM 3007 C "C4'" . G   B 2 21  ? 126.182 129.365 119.430 1.00 50.58  ? 21  G   B "C4'" 1 
ATOM 3008 O "O4'" . G   B 2 21  ? 126.416 129.596 120.846 1.00 53.31  ? 21  G   B "O4'" 1 
ATOM 3009 C "C3'" . G   B 2 21  ? 127.552 129.561 118.811 1.00 47.01  ? 21  G   B "C3'" 1 
ATOM 3010 O "O3'" . G   B 2 21  ? 127.519 129.799 117.420 1.00 52.30  ? 21  G   B "O3'" 1 
ATOM 3011 C "C2'" . G   B 2 21  ? 128.099 130.719 119.623 1.00 48.13  ? 21  G   B "C2'" 1 
ATOM 3012 O "O2'" . G   B 2 21  ? 127.473 131.935 119.244 1.00 49.59  ? 21  G   B "O2'" 1 
ATOM 3013 C "C1'" . G   B 2 21  ? 127.606 130.343 121.015 1.00 51.47  ? 21  G   B "C1'" 1 
ATOM 3014 N N9    . G   B 2 21  ? 128.593 129.499 121.716 1.00 51.84  ? 21  G   B N9    1 
ATOM 3015 C C8    . G   B 2 21  ? 128.448 128.188 122.090 1.00 53.60  ? 21  G   B C8    1 
ATOM 3016 N N7    . G   B 2 21  ? 129.498 127.702 122.691 1.00 50.49  ? 21  G   B N7    1 
ATOM 3017 C C5    . G   B 2 21  ? 130.399 128.754 122.707 1.00 51.57  ? 21  G   B C5    1 
ATOM 3018 C C6    . G   B 2 21  ? 131.720 128.829 123.217 1.00 55.54  ? 21  G   B C6    1 
ATOM 3019 O O6    . G   B 2 21  ? 132.383 127.956 123.789 1.00 59.46  ? 21  G   B O6    1 
ATOM 3020 N N1    . G   B 2 21  ? 132.274 130.087 123.019 1.00 53.30  ? 21  G   B N1    1 
ATOM 3021 C C2    . G   B 2 21  ? 131.648 131.137 122.406 1.00 51.38  ? 21  G   B C2    1 
ATOM 3022 N N2    . G   B 2 21  ? 132.343 132.277 122.304 1.00 50.53  ? 21  G   B N2    1 
ATOM 3023 N N3    . G   B 2 21  ? 130.423 131.079 121.928 1.00 50.96  ? 21  G   B N3    1 
ATOM 3024 C C4    . G   B 2 21  ? 129.858 129.868 122.107 1.00 50.78  ? 21  G   B C4    1 
ATOM 3025 P P     . U   B 2 22  ? 128.625 129.123 116.475 1.00 51.73  ? 22  U   B P     1 
ATOM 3026 O OP1   . U   B 2 22  ? 128.146 129.251 115.081 1.00 63.13  ? 22  U   B OP1   1 
ATOM 3027 O OP2   . U   B 2 22  ? 128.960 127.784 117.016 1.00 45.62  ? 22  U   B OP2   1 
ATOM 3028 O "O5'" . U   B 2 22  ? 129.908 130.043 116.669 1.00 44.42  ? 22  U   B "O5'" 1 
ATOM 3029 C "C5'" . U   B 2 22  ? 129.832 131.449 116.487 1.00 44.88  ? 22  U   B "C5'" 1 
ATOM 3030 C "C4'" . U   B 2 22  ? 131.128 132.125 116.855 1.00 44.14  ? 22  U   B "C4'" 1 
ATOM 3031 O "O4'" . U   B 2 22  ? 131.370 132.006 118.284 1.00 48.13  ? 22  U   B "O4'" 1 
ATOM 3032 C "C3'" . U   B 2 22  ? 132.383 131.544 116.232 1.00 44.21  ? 22  U   B "C3'" 1 
ATOM 3033 O "O3'" . U   B 2 22  ? 132.584 131.933 114.886 1.00 48.21  ? 22  U   B "O3'" 1 
ATOM 3034 C "C2'" . U   B 2 22  ? 133.462 132.040 117.175 1.00 44.34  ? 22  U   B "C2'" 1 
ATOM 3035 O "O2'" . U   B 2 22  ? 133.718 133.416 116.946 1.00 52.67  ? 22  U   B "O2'" 1 
ATOM 3036 C "C1'" . U   B 2 22  ? 132.760 131.905 118.525 1.00 43.40  ? 22  U   B "C1'" 1 
ATOM 3037 N N1    . U   B 2 22  ? 133.045 130.603 119.178 1.00 42.52  ? 22  U   B N1    1 
ATOM 3038 C C2    . U   B 2 22  ? 134.314 130.336 119.671 1.00 45.87  ? 22  U   B C2    1 
ATOM 3039 O O2    . U   B 2 22  ? 135.255 131.104 119.612 1.00 51.81  ? 22  U   B O2    1 
ATOM 3040 N N3    . U   B 2 22  ? 134.477 129.109 120.258 1.00 47.91  ? 22  U   B N3    1 
ATOM 3041 C C4    . U   B 2 22  ? 133.519 128.130 120.404 1.00 47.97  ? 22  U   B C4    1 
ATOM 3042 O O4    . U   B 2 22  ? 133.801 127.067 120.953 1.00 51.82  ? 22  U   B O4    1 
ATOM 3043 C C5    . U   B 2 22  ? 132.241 128.473 119.876 1.00 46.85  ? 22  U   B C5    1 
ATOM 3044 C C6    . U   B 2 22  ? 132.057 129.662 119.304 1.00 47.92  ? 22  U   B C6    1 
ATOM 3045 P P     . U   B 2 23  ? 133.285 130.919 113.856 1.00 48.09  ? 23  U   B P     1 
ATOM 3046 O OP1   . U   B 2 23  ? 133.310 131.563 112.522 1.00 53.62  ? 23  U   B OP1   1 
ATOM 3047 O OP2   . U   B 2 23  ? 132.675 129.579 114.027 1.00 50.13  ? 23  U   B OP2   1 
ATOM 3048 O "O5'" . U   B 2 23  ? 134.788 130.826 114.364 1.00 43.37  ? 23  U   B "O5'" 1 
ATOM 3049 C "C5'" . U   B 2 23  ? 135.649 131.950 114.288 1.00 49.14  ? 23  U   B "C5'" 1 
ATOM 3050 C "C4'" . U   B 2 23  ? 136.985 131.659 114.917 1.00 48.47  ? 23  U   B "C4'" 1 
ATOM 3051 O "O4'" . U   B 2 23  ? 136.805 131.276 116.304 1.00 44.78  ? 23  U   B "O4'" 1 
ATOM 3052 C "C3'" . U   B 2 23  ? 137.751 130.499 114.314 1.00 49.24  ? 23  U   B "C3'" 1 
ATOM 3053 O "O3'" . U   B 2 23  ? 138.440 130.855 113.132 1.00 50.81  ? 23  U   B "O3'" 1 
ATOM 3054 C "C2'" . U   B 2 23  ? 138.672 130.085 115.448 1.00 47.81  ? 23  U   B "C2'" 1 
ATOM 3055 O "O2'" . U   B 2 23  ? 139.787 130.958 115.525 1.00 50.88  ? 23  U   B "O2'" 1 
ATOM 3056 C "C1'" . U   B 2 23  ? 137.784 130.327 116.668 1.00 43.10  ? 23  U   B "C1'" 1 
ATOM 3057 N N1    . U   B 2 23  ? 137.107 129.097 117.146 1.00 43.24  ? 23  U   B N1    1 
ATOM 3058 C C2    . U   B 2 23  ? 137.847 128.150 117.829 1.00 44.28  ? 23  U   B C2    1 
ATOM 3059 O O2    . U   B 2 23  ? 139.040 128.247 118.047 1.00 46.38  ? 23  U   B O2    1 
ATOM 3060 N N3    . U   B 2 23  ? 137.153 127.046 118.246 1.00 42.82  ? 23  U   B N3    1 
ATOM 3061 C C4    . U   B 2 23  ? 135.814 126.791 118.075 1.00 42.43  ? 23  U   B C4    1 
ATOM 3062 O O4    . U   B 2 23  ? 135.333 125.747 118.517 1.00 45.71  ? 23  U   B O4    1 
ATOM 3063 C C5    . U   B 2 23  ? 135.111 127.815 117.371 1.00 43.51  ? 23  U   B C5    1 
ATOM 3064 C C6    . U   B 2 23  ? 135.763 128.903 116.949 1.00 44.67  ? 23  U   B C6    1 
ATOM 3065 P P     . A   B 2 24  ? 138.667 129.764 111.979 1.00 64.82  ? 24  A   B P     1 
ATOM 3066 O OP1   . A   B 2 24  ? 139.074 130.483 110.748 1.00 70.34  ? 24  A   B OP1   1 
ATOM 3067 O OP2   . A   B 2 24  ? 137.488 128.864 111.956 1.00 53.75  ? 24  A   B OP2   1 
ATOM 3068 O "O5'" . A   B 2 24  ? 139.911 128.918 112.495 1.00 51.36  ? 24  A   B "O5'" 1 
ATOM 3069 C "C5'" . A   B 2 24  ? 141.146 129.548 112.795 1.00 49.35  ? 24  A   B "C5'" 1 
ATOM 3070 C "C4'" . A   B 2 24  ? 142.095 128.588 113.460 1.00 51.28  ? 24  A   B "C4'" 1 
ATOM 3071 O "O4'" . A   B 2 24  ? 141.637 128.290 114.800 1.00 49.37  ? 24  A   B "O4'" 1 
ATOM 3072 C "C3'" . A   B 2 24  ? 142.214 127.228 112.800 1.00 55.60  ? 24  A   B "C3'" 1 
ATOM 3073 O "O3'" . A   B 2 24  ? 143.098 127.242 111.696 1.00 65.59  ? 24  A   B "O3'" 1 
ATOM 3074 C "C2'" . A   B 2 24  ? 142.680 126.336 113.942 1.00 54.68  ? 24  A   B "C2'" 1 
ATOM 3075 O "O2'" . A   B 2 24  ? 144.078 126.473 114.145 1.00 58.68  ? 24  A   B "O2'" 1 
ATOM 3076 C "C1'" . A   B 2 24  ? 141.961 126.958 115.135 1.00 51.24  ? 24  A   B "C1'" 1 
ATOM 3077 N N9    . A   B 2 24  ? 140.724 126.252 115.519 1.00 50.35  ? 24  A   B N9    1 
ATOM 3078 C C8    . A   B 2 24  ? 139.443 126.688 115.317 1.00 51.21  ? 24  A   B C8    1 
ATOM 3079 N N7    . A   B 2 24  ? 138.518 125.891 115.782 1.00 46.72  ? 24  A   B N7    1 
ATOM 3080 C C5    . A   B 2 24  ? 139.242 124.859 116.344 1.00 46.69  ? 24  A   B C5    1 
ATOM 3081 C C6    . A   B 2 24  ? 138.838 123.692 117.004 1.00 50.42  ? 24  A   B C6    1 
ATOM 3082 N N6    . A   B 2 24  ? 137.560 123.376 117.208 1.00 53.01  ? 24  A   B N6    1 
ATOM 3083 N N1    . A   B 2 24  ? 139.796 122.853 117.448 1.00 52.48  ? 24  A   B N1    1 
ATOM 3084 C C2    . A   B 2 24  ? 141.079 123.173 117.240 1.00 51.71  ? 24  A   B C2    1 
ATOM 3085 N N3    . A   B 2 24  ? 141.581 124.248 116.630 1.00 51.64  ? 24  A   B N3    1 
ATOM 3086 C C4    . A   B 2 24  ? 140.601 125.062 116.199 1.00 48.77  ? 24  A   B C4    1 
ATOM 3087 P P     . C   B 2 25  ? 142.799 126.330 110.411 1.00 76.06  ? 25  C   B P     1 
ATOM 3088 O OP1   . C   B 2 25  ? 143.719 126.759 109.329 1.00 68.03  ? 25  C   B OP1   1 
ATOM 3089 O OP2   . C   B 2 25  ? 141.335 126.325 110.174 1.00 69.82  ? 25  C   B OP2   1 
ATOM 3090 O "O5'" . C   B 2 25  ? 143.229 124.871 110.878 1.00 68.18  ? 25  C   B "O5'" 1 
ATOM 3091 C "C5'" . C   B 2 25  ? 144.557 124.609 111.299 1.00 62.21  ? 25  C   B "C5'" 1 
ATOM 3092 C "C4'" . C   B 2 25  ? 144.655 123.295 112.027 1.00 61.15  ? 25  C   B "C4'" 1 
ATOM 3093 O "O4'" . C   B 2 25  ? 143.911 123.350 113.271 1.00 61.70  ? 25  C   B "O4'" 1 
ATOM 3094 C "C3'" . C   B 2 25  ? 144.065 122.096 111.313 1.00 65.34  ? 25  C   B "C3'" 1 
ATOM 3095 O "O3'" . C   B 2 25  ? 144.901 121.586 110.293 1.00 70.77  ? 25  C   B "O3'" 1 
ATOM 3096 C "C2'" . C   B 2 25  ? 143.827 121.121 112.455 1.00 64.44  ? 25  C   B "C2'" 1 
ATOM 3097 O "O2'" . C   B 2 25  ? 145.041 120.497 112.842 1.00 66.77  ? 25  C   B "O2'" 1 
ATOM 3098 C "C1'" . C   B 2 25  ? 143.397 122.070 113.576 1.00 62.13  ? 25  C   B "C1'" 1 
ATOM 3099 N N1    . C   B 2 25  ? 141.923 122.149 113.720 1.00 56.55  ? 25  C   B N1    1 
ATOM 3100 C C2    . C   B 2 25  ? 141.260 121.128 114.408 1.00 59.15  ? 25  C   B C2    1 
ATOM 3101 O O2    . C   B 2 25  ? 141.933 120.194 114.869 1.00 62.93  ? 25  C   B O2    1 
ATOM 3102 N N3    . C   B 2 25  ? 139.917 121.185 114.553 1.00 58.65  ? 25  C   B N3    1 
ATOM 3103 C C4    . C   B 2 25  ? 139.237 122.210 114.042 1.00 56.94  ? 25  C   B C4    1 
ATOM 3104 N N4    . C   B 2 25  ? 137.913 122.232 114.207 1.00 58.39  ? 25  C   B N4    1 
ATOM 3105 C C5    . C   B 2 25  ? 139.880 123.265 113.341 1.00 55.44  ? 25  C   B C5    1 
ATOM 3106 C C6    . C   B 2 25  ? 141.208 123.191 113.206 1.00 55.73  ? 25  C   B C6    1 
ATOM 3107 P P     . A   B 2 26  ? 144.246 120.964 108.967 1.00 82.95  ? 26  A   B P     1 
ATOM 3108 O OP1   . A   B 2 26  ? 145.341 120.692 108.003 1.00 85.00  ? 26  A   B OP1   1 
ATOM 3109 O OP2   . A   B 2 26  ? 143.106 121.830 108.572 1.00 74.91  ? 26  A   B OP2   1 
ATOM 3110 O "O5'" . A   B 2 26  ? 143.666 119.564 109.453 1.00 74.09  ? 26  A   B "O5'" 1 
ATOM 3111 C "C5'" . A   B 2 26  ? 144.540 118.555 109.933 1.00 70.31  ? 26  A   B "C5'" 1 
ATOM 3112 C "C4'" . A   B 2 26  ? 143.796 117.446 110.633 1.00 70.89  ? 26  A   B "C4'" 1 
ATOM 3113 O "O4'" . A   B 2 26  ? 143.142 117.945 111.828 1.00 66.83  ? 26  A   B "O4'" 1 
ATOM 3114 C "C3'" . A   B 2 26  ? 142.666 116.797 109.859 1.00 74.84  ? 26  A   B "C3'" 1 
ATOM 3115 O "O3'" . A   B 2 26  ? 143.109 115.892 108.866 1.00 77.36  ? 26  A   B "O3'" 1 
ATOM 3116 C "C2'" . A   B 2 26  ? 141.857 116.145 110.970 1.00 74.42  ? 26  A   B "C2'" 1 
ATOM 3117 O "O2'" . A   B 2 26  ? 142.501 114.967 111.429 1.00 79.53  ? 26  A   B "O2'" 1 
ATOM 3118 C "C1'" . A   B 2 26  ? 141.962 117.204 112.066 1.00 66.73  ? 26  A   B "C1'" 1 
ATOM 3119 N N9    . A   B 2 26  ? 140.804 118.114 112.050 1.00 62.91  ? 26  A   B N9    1 
ATOM 3120 C C8    . A   B 2 26  ? 140.710 119.401 111.587 1.00 64.14  ? 26  A   B C8    1 
ATOM 3121 N N7    . A   B 2 26  ? 139.512 119.922 111.721 1.00 61.59  ? 26  A   B N7    1 
ATOM 3122 C C5    . A   B 2 26  ? 138.771 118.906 112.304 1.00 59.98  ? 26  A   B C5    1 
ATOM 3123 C C6    . A   B 2 26  ? 137.429 118.808 112.709 1.00 58.43  ? 26  A   B C6    1 
ATOM 3124 N N6    . A   B 2 26  ? 136.544 119.796 112.581 1.00 55.00  ? 26  A   B N6    1 
ATOM 3125 N N1    . A   B 2 26  ? 137.018 117.643 113.260 1.00 60.71  ? 26  A   B N1    1 
ATOM 3126 C C2    . A   B 2 26  ? 137.902 116.649 113.391 1.00 62.53  ? 26  A   B C2    1 
ATOM 3127 N N3    . A   B 2 26  ? 139.184 116.621 113.049 1.00 62.59  ? 26  A   B N3    1 
ATOM 3128 C C4    . A   B 2 26  ? 139.556 117.790 112.508 1.00 61.23  ? 26  A   B C4    1 
ATOM 3129 P P     . G   B 2 27  ? 142.243 115.697 107.529 1.00 81.45  ? 27  G   B P     1 
ATOM 3130 O OP1   . G   B 2 27  ? 143.081 114.970 106.545 1.00 84.32  ? 27  G   B OP1   1 
ATOM 3131 O OP2   . G   B 2 27  ? 141.656 117.012 107.168 1.00 73.26  ? 27  G   B OP2   1 
ATOM 3132 O "O5'" . G   B 2 27  ? 141.061 114.731 107.982 1.00 80.92  ? 27  G   B "O5'" 1 
ATOM 3133 C "C5'" . G   B 2 27  ? 141.349 113.439 108.492 1.00 82.72  ? 27  G   B "C5'" 1 
ATOM 3134 C "C4'" . G   B 2 27  ? 140.146 112.799 109.137 1.00 81.12  ? 27  G   B "C4'" 1 
ATOM 3135 O "O4'" . G   B 2 27  ? 139.677 113.600 110.250 1.00 76.92  ? 27  G   B "O4'" 1 
ATOM 3136 C "C3'" . G   B 2 27  ? 138.914 112.638 108.267 1.00 82.99  ? 27  G   B "C3'" 1 
ATOM 3137 O "O3'" . G   B 2 27  ? 139.011 111.543 107.375 1.00 91.80  ? 27  G   B "O3'" 1 
ATOM 3138 C "C2'" . G   B 2 27  ? 137.807 112.481 109.300 1.00 79.54  ? 27  G   B "C2'" 1 
ATOM 3139 O "O2'" . G   B 2 27  ? 137.790 111.159 109.818 1.00 82.22  ? 27  G   B "O2'" 1 
ATOM 3140 C "C1'" . G   B 2 27  ? 138.284 113.423 110.406 1.00 74.30  ? 27  G   B "C1'" 1 
ATOM 3141 N N9    . G   B 2 27  ? 137.612 114.735 110.358 1.00 69.24  ? 27  G   B N9    1 
ATOM 3142 C C8    . G   B 2 27  ? 138.150 115.949 110.019 1.00 68.66  ? 27  G   B C8    1 
ATOM 3143 N N7    . G   B 2 27  ? 137.285 116.925 110.085 1.00 65.30  ? 27  G   B N7    1 
ATOM 3144 C C5    . G   B 2 27  ? 136.106 116.319 110.495 1.00 64.00  ? 27  G   B C5    1 
ATOM 3145 C C6    . G   B 2 27  ? 134.819 116.864 110.741 1.00 64.10  ? 27  G   B C6    1 
ATOM 3146 O O6    . G   B 2 27  ? 134.440 118.036 110.651 1.00 65.73  ? 27  G   B O6    1 
ATOM 3147 N N1    . G   B 2 27  ? 133.915 115.889 111.140 1.00 63.34  ? 27  G   B N1    1 
ATOM 3148 C C2    . G   B 2 27  ? 134.208 114.560 111.283 1.00 65.44  ? 27  G   B C2    1 
ATOM 3149 N N2    . G   B 2 27  ? 133.201 113.771 111.677 1.00 67.14  ? 27  G   B N2    1 
ATOM 3150 N N3    . G   B 2 27  ? 135.399 114.040 111.057 1.00 66.25  ? 27  G   B N3    1 
ATOM 3151 C C4    . G   B 2 27  ? 136.295 114.969 110.670 1.00 65.97  ? 27  G   B C4    1 
ATOM 3152 P P     . U   B 2 28  ? 138.287 111.600 105.944 1.00 95.30  ? 28  U   B P     1 
ATOM 3153 O OP1   . U   B 2 28  ? 138.770 110.444 105.149 1.00 96.09  ? 28  U   B OP1   1 
ATOM 3154 O OP2   . U   B 2 28  ? 138.425 112.977 105.405 1.00 90.41  ? 28  U   B OP2   1 
ATOM 3155 O "O5'" . U   B 2 28  ? 136.750 111.357 106.281 1.00 88.89  ? 28  U   B "O5'" 1 
ATOM 3156 C "C5'" . U   B 2 28  ? 136.319 110.138 106.867 1.00 87.76  ? 28  U   B "C5'" 1 
ATOM 3157 C "C4'" . U   B 2 28  ? 134.873 110.208 107.284 1.00 86.56  ? 28  U   B "C4'" 1 
ATOM 3158 O "O4'" . U   B 2 28  ? 134.706 111.214 108.316 1.00 82.79  ? 28  U   B "O4'" 1 
ATOM 3159 C "C3'" . U   B 2 28  ? 133.891 110.627 106.202 1.00 91.58  ? 28  U   B "C3'" 1 
ATOM 3160 O "O3'" . U   B 2 28  ? 133.535 109.564 105.337 1.00 100.67 ? 28  U   B "O3'" 1 
ATOM 3161 C "C2'" . U   B 2 28  ? 132.722 111.173 107.009 1.00 88.92  ? 28  U   B "C2'" 1 
ATOM 3162 O "O2'" . U   B 2 28  ? 131.918 110.116 107.509 1.00 89.58  ? 28  U   B "O2'" 1 
ATOM 3163 C "C1'" . U   B 2 28  ? 133.442 111.831 108.186 1.00 83.78  ? 28  U   B "C1'" 1 
ATOM 3164 N N1    . U   B 2 28  ? 133.637 113.286 107.990 1.00 78.78  ? 28  U   B N1    1 
ATOM 3165 C C2    . U   B 2 28  ? 132.557 114.125 108.188 1.00 77.29  ? 28  U   B C2    1 
ATOM 3166 O O2    . U   B 2 28  ? 131.448 113.736 108.509 1.00 78.29  ? 28  U   B O2    1 
ATOM 3167 N N3    . U   B 2 28  ? 132.807 115.458 107.996 1.00 75.64  ? 28  U   B N3    1 
ATOM 3168 C C4    . U   B 2 28  ? 134.008 116.029 107.634 1.00 73.71  ? 28  U   B C4    1 
ATOM 3169 O O4    . U   B 2 28  ? 134.092 117.249 107.498 1.00 72.72  ? 28  U   B O4    1 
ATOM 3170 C C5    . U   B 2 28  ? 135.077 115.101 107.452 1.00 74.43  ? 28  U   B C5    1 
ATOM 3171 C C6    . U   B 2 28  ? 134.860 113.797 107.634 1.00 77.36  ? 28  U   B C6    1 
ATOM 3172 P P     . U   B 2 29  ? 133.149 109.864 103.807 1.00 102.91 ? 29  U   B P     1 
ATOM 3173 O OP1   . U   B 2 29  ? 133.135 108.572 103.077 1.00 106.04 ? 29  U   B OP1   1 
ATOM 3174 O OP2   . U   B 2 29  ? 134.010 110.972 103.323 1.00 98.67  ? 29  U   B OP2   1 
ATOM 3175 O "O5'" . U   B 2 29  ? 131.654 110.409 103.885 1.00 96.65  ? 29  U   B "O5'" 1 
ATOM 3176 C "C5'" . U   B 2 29  ? 130.612 109.607 104.420 1.00 96.65  ? 29  U   B "C5'" 1 
ATOM 3177 C "C4'" . U   B 2 29  ? 129.379 110.425 104.703 1.00 95.58  ? 29  U   B "C4'" 1 
ATOM 3178 O "O4'" . U   B 2 29  ? 129.694 111.476 105.652 1.00 89.22  ? 29  U   B "O4'" 1 
ATOM 3179 C "C3'" . U   B 2 29  ? 128.792 111.168 103.516 1.00 99.30  ? 29  U   B "C3'" 1 
ATOM 3180 O "O3'" . U   B 2 29  ? 127.989 110.342 102.692 1.00 102.28 ? 29  U   B "O3'" 1 
ATOM 3181 C "C2'" . U   B 2 29  ? 128.024 112.304 104.178 1.00 97.00  ? 29  U   B "C2'" 1 
ATOM 3182 O "O2'" . U   B 2 29  ? 126.777 111.843 104.674 1.00 98.68  ? 29  U   B "O2'" 1 
ATOM 3183 C "C1'" . U   B 2 29  ? 128.926 112.627 105.370 1.00 91.62  ? 29  U   B "C1'" 1 
ATOM 3184 N N1    . U   B 2 29  ? 129.843 113.762 105.110 1.00 88.93  ? 29  U   B N1    1 
ATOM 3185 C C2    . U   B 2 29  ? 129.349 115.052 105.198 1.00 86.57  ? 29  U   B C2    1 
ATOM 3186 O O2    . U   B 2 29  ? 128.186 115.301 105.460 1.00 86.10  ? 29  U   B O2    1 
ATOM 3187 N N3    . U   B 2 29  ? 130.265 116.048 104.951 1.00 84.27  ? 29  U   B N3    1 
ATOM 3188 C C4    . U   B 2 29  ? 131.601 115.887 104.643 1.00 84.92  ? 29  U   B C4    1 
ATOM 3189 O O4    . U   B 2 29  ? 132.317 116.869 104.447 1.00 86.60  ? 29  U   B O4    1 
ATOM 3190 C C5    . U   B 2 29  ? 132.036 114.529 104.581 1.00 86.12  ? 29  U   B C5    1 
ATOM 3191 C C6    . U   B 2 29  ? 131.166 113.544 104.813 1.00 88.54  ? 29  U   B C6    1 
ATOM 3192 P P     . A   B 2 30  ? 127.975 110.565 101.102 1.00 105.87 ? 30  A   B P     1 
ATOM 3193 O OP1   . A   B 2 30  ? 127.241 109.431 100.486 1.00 106.25 ? 30  A   B OP1   1 
ATOM 3194 O OP2   . A   B 2 30  ? 129.362 110.864 100.667 1.00 103.47 ? 30  A   B OP2   1 
ATOM 3195 O "O5'" . A   B 2 30  ? 127.097 111.879 100.910 1.00 103.70 ? 30  A   B "O5'" 1 
ATOM 3196 C "C5'" . A   B 2 30  ? 125.727 111.893 101.281 1.00 103.34 ? 30  A   B "C5'" 1 
ATOM 3197 C "C4'" . A   B 2 30  ? 125.141 113.279 101.197 1.00 104.88 ? 30  A   B "C4'" 1 
ATOM 3198 O "O4'" . A   B 2 30  ? 125.694 114.119 102.241 1.00 100.06 ? 30  A   B "O4'" 1 
ATOM 3199 C "C3'" . A   B 2 30  ? 125.425 114.050 99.920  1.00 110.20 ? 30  A   B "C3'" 1 
ATOM 3200 O "O3'" . A   B 2 30  ? 124.579 113.673 98.849  1.00 113.52 ? 30  A   B "O3'" 1 
ATOM 3201 C "C2'" . A   B 2 30  ? 125.244 115.496 100.358 1.00 108.22 ? 30  A   B "C2'" 1 
ATOM 3202 O "O2'" . A   B 2 30  ? 123.866 115.829 100.425 1.00 111.50 ? 30  A   B "O2'" 1 
ATOM 3203 C "C1'" . A   B 2 30  ? 125.794 115.451 101.782 1.00 100.79 ? 30  A   B "C1'" 1 
ATOM 3204 N N9    . A   B 2 30  ? 127.204 115.873 101.856 1.00 97.81  ? 30  A   B N9    1 
ATOM 3205 C C8    . A   B 2 30  ? 128.304 115.081 102.062 1.00 97.13  ? 30  A   B C8    1 
ATOM 3206 N N7    . A   B 2 30  ? 129.435 115.740 102.097 1.00 96.95  ? 30  A   B N7    1 
ATOM 3207 C C5    . A   B 2 30  ? 129.051 117.057 101.901 1.00 98.04  ? 30  A   B C5    1 
ATOM 3208 C C6    . A   B 2 30  ? 129.782 118.251 101.827 1.00 98.22  ? 30  A   B C6    1 
ATOM 3209 N N6    . A   B 2 30  ? 131.108 118.305 101.951 1.00 98.70  ? 30  A   B N6    1 
ATOM 3210 N N1    . A   B 2 30  ? 129.101 119.400 101.623 1.00 98.63  ? 30  A   B N1    1 
ATOM 3211 C C2    . A   B 2 30  ? 127.768 119.341 101.500 1.00 99.28  ? 30  A   B C2    1 
ATOM 3212 N N3    . A   B 2 30  ? 126.970 118.278 101.547 1.00 98.53  ? 30  A   B N3    1 
ATOM 3213 C C4    . A   B 2 30  ? 127.681 117.156 101.753 1.00 98.74  ? 30  A   B C4    1 
ATOM 3214 P P     . A   B 2 31  ? 125.113 113.751 97.338  1.00 116.98 ? 31  A   B P     1 
ATOM 3215 O OP1   . A   B 2 31  ? 124.121 113.071 96.469  1.00 113.08 ? 31  A   B OP1   1 
ATOM 3216 O OP2   . A   B 2 31  ? 126.528 113.302 97.330  1.00 115.89 ? 31  A   B OP2   1 
ATOM 3217 O "O5'" . A   B 2 31  ? 125.080 115.307 97.000  1.00 119.86 ? 31  A   B "O5'" 1 
ATOM 3218 C "C5'" . A   B 2 31  ? 123.852 116.019 96.981  1.00 118.56 ? 31  A   B "C5'" 1 
ATOM 3219 C "C4'" . A   B 2 31  ? 124.071 117.506 96.869  1.00 121.11 ? 31  A   B "C4'" 1 
ATOM 3220 O "O4'" . A   B 2 31  ? 124.741 118.004 98.056  1.00 114.04 ? 31  A   B "O4'" 1 
ATOM 3221 C "C3'" . A   B 2 31  ? 124.965 117.970 95.731  1.00 128.88 ? 31  A   B "C3'" 1 
ATOM 3222 O "O3'" . A   B 2 31  ? 124.311 117.999 94.476  1.00 133.00 ? 31  A   B "O3'" 1 
ATOM 3223 C "C2'" . A   B 2 31  ? 125.422 119.337 96.215  1.00 129.96 ? 31  A   B "C2'" 1 
ATOM 3224 O "O2'" . A   B 2 31  ? 124.390 120.298 96.045  1.00 135.04 ? 31  A   B "O2'" 1 
ATOM 3225 C "C1'" . A   B 2 31  ? 125.593 119.077 97.709  1.00 118.97 ? 31  A   B "C1'" 1 
ATOM 3226 N N9    . A   B 2 31  ? 126.981 118.709 98.043  1.00 115.02 ? 31  A   B N9    1 
ATOM 3227 C C8    . A   B 2 31  ? 127.475 117.469 98.355  1.00 112.58 ? 31  A   B C8    1 
ATOM 3228 N N7    . A   B 2 31  ? 128.761 117.460 98.607  1.00 110.05 ? 31  A   B N7    1 
ATOM 3229 C C5    . A   B 2 31  ? 129.136 118.784 98.444  1.00 112.88 ? 31  A   B C5    1 
ATOM 3230 C C6    . A   B 2 31  ? 130.370 119.441 98.570  1.00 117.79 ? 31  A   B C6    1 
ATOM 3231 N N6    . A   B 2 31  ? 131.503 118.821 98.900  1.00 119.67 ? 31  A   B N6    1 
ATOM 3232 N N1    . A   B 2 31  ? 130.405 120.772 98.341  1.00 122.12 ? 31  A   B N1    1 
ATOM 3233 C C2    . A   B 2 31  ? 129.268 121.399 98.009  1.00 121.52 ? 31  A   B C2    1 
ATOM 3234 N N3    . A   B 2 31  ? 128.048 120.889 97.862  1.00 119.27 ? 31  A   B N3    1 
ATOM 3235 C C4    . A   B 2 31  ? 128.051 119.565 98.096  1.00 115.64 ? 31  A   B C4    1 
ATOM 3236 P P     . G   B 2 32  ? 125.153 117.733 93.133  1.00 138.22 ? 32  G   B P     1 
ATOM 3237 O OP1   . G   B 2 32  ? 124.194 117.686 92.001  1.00 139.30 ? 32  G   B OP1   1 
ATOM 3238 O OP2   . G   B 2 32  ? 126.059 116.583 93.377  1.00 132.29 ? 32  G   B OP2   1 
ATOM 3239 O "O5'" . G   B 2 32  ? 126.048 119.042 92.970  1.00 139.96 ? 32  G   B "O5'" 1 
ATOM 3240 C "C5'" . G   B 2 32  ? 125.457 120.286 92.629  1.00 141.49 ? 32  G   B "C5'" 1 
ATOM 3241 C "C4'" . G   B 2 32  ? 126.439 121.428 92.724  1.00 144.16 ? 32  G   B "C4'" 1 
ATOM 3242 O "O4'" . G   B 2 32  ? 127.033 121.478 94.048  1.00 136.85 ? 32  G   B "O4'" 1 
ATOM 3243 C "C3'" . G   B 2 32  ? 127.641 121.374 91.798  1.00 153.17 ? 32  G   B "C3'" 1 
ATOM 3244 O "O3'" . G   B 2 32  ? 127.345 121.745 90.464  1.00 158.15 ? 32  G   B "O3'" 1 
ATOM 3245 C "C2'" . G   B 2 32  ? 128.620 122.312 92.488  1.00 152.13 ? 32  G   B "C2'" 1 
ATOM 3246 O "O2'" . G   B 2 32  ? 128.267 123.667 92.249  1.00 155.46 ? 32  G   B "O2'" 1 
ATOM 3247 C "C1'" . G   B 2 32  ? 128.348 121.995 93.959  1.00 141.65 ? 32  G   B "C1'" 1 
ATOM 3248 N N9    . G   B 2 32  ? 129.301 120.999 94.482  1.00 137.21 ? 32  G   B N9    1 
ATOM 3249 C C8    . G   B 2 32  ? 129.084 119.665 94.725  1.00 132.92 ? 32  G   B C8    1 
ATOM 3250 N N7    . G   B 2 32  ? 130.141 119.053 95.185  1.00 131.79 ? 32  G   B N7    1 
ATOM 3251 C C5    . G   B 2 32  ? 131.114 120.041 95.247  1.00 136.52 ? 32  G   B C5    1 
ATOM 3252 C C6    . G   B 2 32  ? 132.469 119.976 95.664  1.00 140.73 ? 32  G   B C6    1 
ATOM 3253 O O6    . G   B 2 32  ? 133.090 118.996 96.087  1.00 140.15 ? 32  G   B O6    1 
ATOM 3254 N N1    . G   B 2 32  ? 133.102 121.213 95.565  1.00 144.40 ? 32  G   B N1    1 
ATOM 3255 C C2    . G   B 2 32  ? 132.501 122.364 95.117  1.00 145.66 ? 32  G   B C2    1 
ATOM 3256 N N2    . G   B 2 32  ? 133.276 123.459 95.090  1.00 148.59 ? 32  G   B N2    1 
ATOM 3257 N N3    . G   B 2 32  ? 131.241 122.438 94.721  1.00 142.23 ? 32  G   B N3    1 
ATOM 3258 C C4    . G   B 2 32  ? 130.611 121.247 94.813  1.00 138.63 ? 32  G   B C4    1 
ATOM 3259 P P     . G   B 2 33  ? 128.212 121.134 89.257  1.00 164.60 ? 33  G   B P     1 
ATOM 3260 O OP1   . G   B 2 33  ? 127.545 121.500 87.982  1.00 164.40 ? 33  G   B OP1   1 
ATOM 3261 O OP2   . G   B 2 33  ? 128.484 119.708 89.566  1.00 160.78 ? 33  G   B OP2   1 
ATOM 3262 O "O5'" . G   B 2 33  ? 129.594 121.923 89.333  1.00 165.63 ? 33  G   B "O5'" 1 
ATOM 3263 C "C5'" . G   B 2 33  ? 129.662 123.301 89.002  1.00 166.28 ? 33  G   B "C5'" 1 
ATOM 3264 C "C4'" . G   B 2 33  ? 131.020 123.881 89.306  1.00 167.45 ? 33  G   B "C4'" 1 
ATOM 3265 O "O4'" . G   B 2 33  ? 131.338 123.681 90.708  1.00 159.83 ? 33  G   B "O4'" 1 
ATOM 3266 C "C3'" . G   B 2 33  ? 132.196 123.257 88.572  1.00 173.12 ? 33  G   B "C3'" 1 
ATOM 3267 O "O3'" . G   B 2 33  ? 132.343 123.738 87.248  1.00 175.55 ? 33  G   B "O3'" 1 
ATOM 3268 C "C2'" . G   B 2 33  ? 133.369 123.602 89.477  1.00 173.82 ? 33  G   B "C2'" 1 
ATOM 3269 O "O2'" . G   B 2 33  ? 133.770 124.950 89.286  1.00 178.47 ? 33  G   B "O2'" 1 
ATOM 3270 C "C1'" . G   B 2 33  ? 132.728 123.481 90.860  1.00 164.25 ? 33  G   B "C1'" 1 
ATOM 3271 N N9    . G   B 2 33  ? 132.957 122.156 91.465  1.00 157.88 ? 33  G   B N9    1 
ATOM 3272 C C8    . G   B 2 33  ? 132.031 121.167 91.690  1.00 153.70 ? 33  G   B C8    1 
ATOM 3273 N N7    . G   B 2 33  ? 132.544 120.105 92.249  1.00 153.99 ? 33  G   B N7    1 
ATOM 3274 C C5    . G   B 2 33  ? 133.889 120.411 92.405  1.00 160.98 ? 33  G   B C5    1 
ATOM 3275 C C6    . G   B 2 33  ? 134.954 119.647 92.949  1.00 165.92 ? 33  G   B C6    1 
ATOM 3276 O O6    . G   B 2 33  ? 134.913 118.509 93.428  1.00 165.55 ? 33  G   B O6    1 
ATOM 3277 N N1    . G   B 2 33  ? 136.162 120.341 92.913  1.00 170.44 ? 33  G   B N1    1 
ATOM 3278 C C2    . G   B 2 33  ? 136.320 121.606 92.406  1.00 172.37 ? 33  G   B C2    1 
ATOM 3279 N N2    . G   B 2 33  ? 137.556 122.124 92.451  1.00 176.21 ? 33  G   B N2    1 
ATOM 3280 N N3    . G   B 2 33  ? 135.337 122.327 91.897  1.00 169.12 ? 33  G   B N3    1 
ATOM 3281 C C4    . G   B 2 33  ? 134.158 121.673 91.926  1.00 163.12 ? 33  G   B C4    1 
ATOM 3282 P P     . C   B 2 34  ? 133.000 122.803 86.119  1.00 179.95 ? 34  C   B P     1 
ATOM 3283 O OP1   . C   B 2 34  ? 132.862 123.498 84.814  1.00 182.07 ? 34  C   B OP1   1 
ATOM 3284 O OP2   . C   B 2 34  ? 132.463 121.429 86.285  1.00 175.15 ? 34  C   B OP2   1 
ATOM 3285 O "O5'" . C   B 2 34  ? 134.548 122.771 86.493  1.00 186.40 ? 34  C   B "O5'" 1 
ATOM 3286 C "C5'" . C   B 2 34  ? 135.363 123.922 86.331  1.00 189.61 ? 34  C   B "C5'" 1 
ATOM 3287 C "C4'" . C   B 2 34  ? 136.776 123.661 86.783  1.00 193.92 ? 34  C   B "C4'" 1 
ATOM 3288 O "O4'" . C   B 2 34  ? 136.777 123.258 88.179  1.00 189.97 ? 34  C   B "O4'" 1 
ATOM 3289 C "C3'" . C   B 2 34  ? 137.498 122.526 86.074  1.00 200.57 ? 34  C   B "C3'" 1 
ATOM 3290 O "O3'" . C   B 2 34  ? 138.032 122.902 84.817  1.00 204.44 ? 34  C   B "O3'" 1 
ATOM 3291 C "C2'" . C   B 2 34  ? 138.556 122.122 87.088  1.00 202.49 ? 34  C   B "C2'" 1 
ATOM 3292 O "O2'" . C   B 2 34  ? 139.650 123.027 87.060  1.00 204.38 ? 34  C   B "O2'" 1 
ATOM 3293 C "C1'" . C   B 2 34  ? 137.803 122.313 88.407  1.00 194.67 ? 34  C   B "C1'" 1 
ATOM 3294 N N1    . C   B 2 34  ? 137.193 121.053 88.904  1.00 190.92 ? 34  C   B N1    1 
ATOM 3295 C C2    . C   B 2 34  ? 138.000 120.067 89.495  1.00 195.64 ? 34  C   B C2    1 
ATOM 3296 O O2    . C   B 2 34  ? 139.223 120.259 89.588  1.00 199.17 ? 34  C   B O2    1 
ATOM 3297 N N3    . C   B 2 34  ? 137.424 118.927 89.945  1.00 193.21 ? 34  C   B N3    1 
ATOM 3298 C C4    . C   B 2 34  ? 136.107 118.750 89.833  1.00 186.70 ? 34  C   B C4    1 
ATOM 3299 N N4    . C   B 2 34  ? 135.582 117.612 90.292  1.00 183.92 ? 34  C   B N4    1 
ATOM 3300 C C5    . C   B 2 34  ? 135.263 119.733 89.246  1.00 180.56 ? 34  C   B C5    1 
ATOM 3301 C C6    . C   B 2 34  ? 135.843 120.854 88.804  1.00 183.16 ? 34  C   B C6    1 
ATOM 3302 P P     . U   B 2 35  ? 138.159 121.816 83.641  1.00 209.97 ? 35  U   B P     1 
ATOM 3303 O OP1   . U   B 2 35  ? 138.509 122.532 82.388  1.00 214.66 ? 35  U   B OP1   1 
ATOM 3304 O OP2   . U   B 2 35  ? 136.949 120.957 83.684  1.00 199.81 ? 35  U   B OP2   1 
ATOM 3305 O "O5'" . U   B 2 35  ? 139.409 120.924 84.068  1.00 216.18 ? 35  U   B "O5'" 1 
ATOM 3306 C "C5'" . U   B 2 35  ? 140.707 121.490 84.171  1.00 220.22 ? 35  U   B "C5'" 1 
ATOM 3307 C "C4'" . U   B 2 35  ? 141.682 120.533 84.810  1.00 224.43 ? 35  U   B "C4'" 1 
ATOM 3308 O "O4'" . U   B 2 35  ? 141.245 120.201 86.156  1.00 222.37 ? 35  U   B "O4'" 1 
ATOM 3309 C "C3'" . U   B 2 35  ? 141.830 119.181 84.132  1.00 231.07 ? 35  U   B "C3'" 1 
ATOM 3310 O "O3'" . U   B 2 35  ? 142.671 119.219 82.993  1.00 236.02 ? 35  U   B "O3'" 1 
ATOM 3311 C "C2'" . U   B 2 35  ? 142.363 118.306 85.258  1.00 232.69 ? 35  U   B "C2'" 1 
ATOM 3312 O "O2'" . U   B 2 35  ? 143.753 118.526 85.450  1.00 234.05 ? 35  U   B "O2'" 1 
ATOM 3313 C "C1'" . U   B 2 35  ? 141.612 118.871 86.465  1.00 226.28 ? 35  U   B "C1'" 1 
ATOM 3314 N N1    . U   B 2 35  ? 140.388 118.097 86.792  1.00 222.01 ? 35  U   B N1    1 
ATOM 3315 C C2    . U   B 2 35  ? 140.514 116.865 87.422  1.00 223.27 ? 35  U   B C2    1 
ATOM 3316 O O2    . U   B 2 35  ? 141.583 116.362 87.723  1.00 225.62 ? 35  U   B O2    1 
ATOM 3317 N N3    . U   B 2 35  ? 139.330 116.220 87.692  1.00 219.01 ? 35  U   B N3    1 
ATOM 3318 C C4    . U   B 2 35  ? 138.056 116.673 87.409  1.00 212.54 ? 35  U   B C4    1 
ATOM 3319 O O4    . U   B 2 35  ? 137.076 115.989 87.709  1.00 208.37 ? 35  U   B O4    1 
ATOM 3320 C C5    . U   B 2 35  ? 138.007 117.949 86.766  1.00 211.26 ? 35  U   B C5    1 
ATOM 3321 C C6    . U   B 2 35  ? 139.142 118.597 86.492  1.00 214.77 ? 35  U   B C6    1 
ATOM 3322 P P     . C   B 2 36  ? 142.436 118.187 81.783  1.00 239.24 ? 36  C   B P     1 
ATOM 3323 O OP1   . C   B 2 36  ? 143.282 118.617 80.640  1.00 241.37 ? 36  C   B OP1   1 
ATOM 3324 O OP2   . C   B 2 36  ? 140.973 118.019 81.594  1.00 233.46 ? 36  C   B OP2   1 
ATOM 3325 O "O5'" . C   B 2 36  ? 143.019 116.811 82.332  1.00 243.93 ? 36  C   B "O5'" 1 
ATOM 3326 C "C5'" . C   B 2 36  ? 144.403 116.663 82.609  1.00 246.15 ? 36  C   B "C5'" 1 
ATOM 3327 C "C4'" . C   B 2 36  ? 144.680 115.366 83.323  1.00 249.93 ? 36  C   B "C4'" 1 
ATOM 3328 O "O4'" . C   B 2 36  ? 143.938 115.326 84.571  1.00 248.59 ? 36  C   B "O4'" 1 
ATOM 3329 C "C3'" . C   B 2 36  ? 144.243 114.106 82.595  1.00 255.83 ? 36  C   B "C3'" 1 
ATOM 3330 O "O3'" . C   B 2 36  ? 145.167 113.687 81.605  1.00 261.08 ? 36  C   B "O3'" 1 
ATOM 3331 C "C2'" . C   B 2 36  ? 144.072 113.107 83.730  1.00 255.84 ? 36  C   B "C2'" 1 
ATOM 3332 O "O2'" . C   B 2 36  ? 145.328 112.587 84.138  1.00 258.19 ? 36  C   B "O2'" 1 
ATOM 3333 C "C1'" . C   B 2 36  ? 143.532 114.001 84.848  1.00 250.57 ? 36  C   B "C1'" 1 
ATOM 3334 N N1    . C   B 2 36  ? 142.051 113.962 84.951  1.00 246.09 ? 36  C   B N1    1 
ATOM 3335 C C2    . C   B 2 36  ? 141.419 112.854 85.533  1.00 245.10 ? 36  C   B C2    1 
ATOM 3336 O O2    . C   B 2 36  ? 142.112 111.909 85.946  1.00 247.01 ? 36  C   B O2    1 
ATOM 3337 N N3    . C   B 2 36  ? 140.068 112.839 85.625  1.00 240.22 ? 36  C   B N3    1 
ATOM 3338 C C4    . C   B 2 36  ? 139.351 113.870 85.174  1.00 236.24 ? 36  C   B C4    1 
ATOM 3339 N N4    . C   B 2 36  ? 138.022 113.818 85.285  1.00 230.61 ? 36  C   B N4    1 
ATOM 3340 C C5    . C   B 2 36  ? 139.963 115.010 84.585  1.00 236.48 ? 36  C   B C5    1 
ATOM 3341 C C6    . C   B 2 36  ? 141.296 115.009 84.498  1.00 240.86 ? 36  C   B C6    1 
ATOM 3342 P P     . U   B 2 37  ? 144.648 112.960 80.269  1.00 266.33 ? 37  U   B P     1 
ATOM 3343 O OP1   . U   B 2 37  ? 145.803 112.823 79.345  1.00 267.87 ? 37  U   B OP1   1 
ATOM 3344 O OP2   . U   B 2 37  ? 143.419 113.657 79.811  1.00 264.70 ? 37  U   B OP2   1 
ATOM 3345 O "O5'" . U   B 2 37  ? 144.229 111.502 80.756  1.00 267.34 ? 37  U   B "O5'" 1 
ATOM 3346 C "C5'" . U   B 2 37  ? 145.189 110.610 81.304  1.00 269.32 ? 37  U   B "C5'" 1 
ATOM 3347 C "C4'" . U   B 2 37  ? 144.528 109.422 81.955  1.00 271.27 ? 37  U   B "C4'" 1 
ATOM 3348 O "O4'" . U   B 2 37  ? 143.691 109.858 83.057  1.00 268.20 ? 37  U   B "O4'" 1 
ATOM 3349 C "C3'" . U   B 2 37  ? 143.582 108.626 81.073  1.00 274.94 ? 37  U   B "C3'" 1 
ATOM 3350 O "O3'" . U   B 2 37  ? 144.253 107.736 80.201  1.00 280.24 ? 37  U   B "O3'" 1 
ATOM 3351 C "C2'" . U   B 2 37  ? 142.687 107.932 82.091  1.00 273.62 ? 37  U   B "C2'" 1 
ATOM 3352 O "O2'" . U   B 2 37  ? 143.346 106.807 82.654  1.00 275.67 ? 37  U   B "O2'" 1 
ATOM 3353 C "C1'" . U   B 2 37  ? 142.566 109.008 83.172  1.00 268.30 ? 37  U   B "C1'" 1 
ATOM 3354 N N1    . U   B 2 37  ? 141.330 109.820 83.041  1.00 262.38 ? 37  U   B N1    1 
ATOM 3355 C C2    . U   B 2 37  ? 140.132 109.280 83.484  1.00 258.27 ? 37  U   B C2    1 
ATOM 3356 O O2    . U   B 2 37  ? 140.036 108.165 83.968  1.00 258.04 ? 37  U   B O2    1 
ATOM 3357 N N3    . U   B 2 37  ? 139.032 110.093 83.338  1.00 254.84 ? 37  U   B N3    1 
ATOM 3358 C C4    . U   B 2 37  ? 139.011 111.369 82.809  1.00 252.76 ? 37  U   B C4    1 
ATOM 3359 O O4    . U   B 2 37  ? 137.951 111.992 82.736  1.00 250.23 ? 37  U   B O4    1 
ATOM 3360 C C5    . U   B 2 37  ? 140.283 111.857 82.379  1.00 254.73 ? 37  U   B C5    1 
ATOM 3361 C C6    . U   B 2 37  ? 141.367 111.088 82.509  1.00 259.49 ? 37  U   B C6    1 
ATOM 3362 P P     . G   B 2 38  ? 143.766 107.593 78.678  1.00 283.33 ? 38  G   B P     1 
ATOM 3363 O OP1   . G   B 2 38  ? 144.810 106.848 77.929  1.00 285.88 ? 38  G   B OP1   1 
ATOM 3364 O OP2   . G   B 2 38  ? 143.339 108.935 78.208  1.00 277.81 ? 38  G   B OP2   1 
ATOM 3365 O "O5'" . G   B 2 38  ? 142.470 106.674 78.779  1.00 283.68 ? 38  G   B "O5'" 1 
ATOM 3366 C "C5'" . G   B 2 38  ? 142.544 105.375 79.348  1.00 284.60 ? 38  G   B "C5'" 1 
ATOM 3367 C "C4'" . G   B 2 38  ? 141.178 104.848 79.706  1.00 284.06 ? 38  G   B "C4'" 1 
ATOM 3368 O "O4'" . G   B 2 38  ? 140.620 105.616 80.805  1.00 279.49 ? 38  G   B "O4'" 1 
ATOM 3369 C "C3'" . G   B 2 38  ? 140.119 104.947 78.621  1.00 285.43 ? 38  G   B "C3'" 1 
ATOM 3370 O "O3'" . G   B 2 38  ? 140.226 103.929 77.642  1.00 289.76 ? 38  G   B "O3'" 1 
ATOM 3371 C "C2'" . G   B 2 38  ? 138.826 104.902 79.422  1.00 282.59 ? 38  G   B "C2'" 1 
ATOM 3372 O "O2'" . G   B 2 38  ? 138.530 103.573 79.826  1.00 284.43 ? 38  G   B "O2'" 1 
ATOM 3373 C "C1'" . G   B 2 38  ? 139.217 105.708 80.662  1.00 277.96 ? 38  G   B "C1'" 1 
ATOM 3374 N N9    . G   B 2 38  ? 138.844 107.129 80.530  1.00 272.13 ? 38  G   B N9    1 
ATOM 3375 C C8    . G   B 2 38  ? 139.663 108.195 80.245  1.00 269.98 ? 38  G   B C8    1 
ATOM 3376 N N7    . G   B 2 38  ? 139.024 109.332 80.190  1.00 266.06 ? 38  G   B N7    1 
ATOM 3377 C C5    . G   B 2 38  ? 137.702 108.998 80.455  1.00 264.81 ? 38  G   B C5    1 
ATOM 3378 C C6    . G   B 2 38  ? 136.539 109.808 80.527  1.00 262.09 ? 38  G   B C6    1 
ATOM 3379 O O6    . G   B 2 38  ? 136.440 111.032 80.377  1.00 257.82 ? 38  G   B O6    1 
ATOM 3380 N N1    . G   B 2 38  ? 135.408 109.053 80.820  1.00 264.38 ? 38  G   B N1    1 
ATOM 3381 C C2    . G   B 2 38  ? 135.393 107.694 81.013  1.00 268.01 ? 38  G   B C2    1 
ATOM 3382 N N2    . G   B 2 38  ? 134.203 107.140 81.284  1.00 270.03 ? 38  G   B N2    1 
ATOM 3383 N N3    . G   B 2 38  ? 136.467 106.928 80.944  1.00 269.47 ? 38  G   B N3    1 
ATOM 3384 C C4    . G   B 2 38  ? 137.577 107.642 80.665  1.00 268.62 ? 38  G   B C4    1 
ATOM 3385 P P     . A   B 2 39  ? 140.276 104.322 76.085  1.00 293.02 ? 39  A   B P     1 
ATOM 3386 O OP1   . A   B 2 39  ? 140.217 103.074 75.283  1.00 293.14 ? 39  A   B OP1   1 
ATOM 3387 O OP2   . A   B 2 39  ? 141.406 105.265 75.889  1.00 291.70 ? 39  A   B OP2   1 
ATOM 3388 O "O5'" . A   B 2 39  ? 138.921 105.127 75.855  1.00 290.49 ? 39  A   B "O5'" 1 
ATOM 3389 C "C5'" . A   B 2 39  ? 138.563 105.609 74.568  1.00 289.05 ? 39  A   B "C5'" 1 
ATOM 3390 C "C4'" . A   B 2 39  ? 137.152 105.214 74.215  1.00 287.98 ? 39  A   B "C4'" 1 
ATOM 3391 O "O4'" . A   B 2 39  ? 137.102 103.792 73.933  1.00 288.84 ? 39  A   B "O4'" 1 
ATOM 3392 C "C3'" . A   B 2 39  ? 136.117 105.415 75.311  1.00 286.78 ? 39  A   B "C3'" 1 
ATOM 3393 O "O3'" . A   B 2 39  ? 135.635 106.747 75.372  1.00 283.98 ? 39  A   B "O3'" 1 
ATOM 3394 C "C2'" . A   B 2 39  ? 135.042 104.396 74.954  1.00 286.32 ? 39  A   B "C2'" 1 
ATOM 3395 O "O2'" . A   B 2 39  ? 134.205 104.891 73.919  1.00 283.44 ? 39  A   B "O2'" 1 
ATOM 3396 C "C1'" . A   B 2 39  ? 135.882 103.250 74.389  1.00 288.24 ? 39  A   B "C1'" 1 
ATOM 3397 N N9    . A   B 2 39  ? 136.178 102.208 75.391  1.00 289.28 ? 39  A   B N9    1 
ATOM 3398 C C8    . A   B 2 39  ? 137.402 101.898 75.929  1.00 289.84 ? 39  A   B C8    1 
ATOM 3399 N N7    . A   B 2 39  ? 137.372 100.912 76.791  1.00 289.70 ? 39  A   B N7    1 
ATOM 3400 C C5    . A   B 2 39  ? 136.036 100.542 76.820  1.00 288.63 ? 39  A   B C5    1 
ATOM 3401 C C6    . A   B 2 39  ? 135.345 99.551  77.540  1.00 288.33 ? 39  A   B C6    1 
ATOM 3402 N N6    . A   B 2 39  ? 135.933 98.720  78.403  1.00 289.51 ? 39  A   B N6    1 
ATOM 3403 N N1    . A   B 2 39  ? 134.012 99.441  77.340  1.00 287.59 ? 39  A   B N1    1 
ATOM 3404 C C2    . A   B 2 39  ? 133.420 100.273 76.474  1.00 286.94 ? 39  A   B C2    1 
ATOM 3405 N N3    . A   B 2 39  ? 133.963 101.243 75.740  1.00 287.33 ? 39  A   B N3    1 
ATOM 3406 C C4    . A   B 2 39  ? 135.288 101.327 75.961  1.00 288.19 ? 39  A   B C4    1 
ATOM 3407 P P     . A   B 2 40  ? 135.806 107.615 76.715  1.00 279.27 ? 40  A   B P     1 
ATOM 3408 O OP1   . A   B 2 40  ? 135.924 109.044 76.331  1.00 275.97 ? 40  A   B OP1   1 
ATOM 3409 O OP2   . A   B 2 40  ? 136.872 106.984 77.534  1.00 279.37 ? 40  A   B OP2   1 
ATOM 3410 O "O5'" . A   B 2 40  ? 134.420 107.425 77.477  1.00 278.31 ? 40  A   B "O5'" 1 
ATOM 3411 C "C5'" . A   B 2 40  ? 133.185 107.684 76.824  1.00 278.44 ? 40  A   B "C5'" 1 
ATOM 3412 C "C4'" . A   B 2 40  ? 132.134 106.683 77.230  1.00 279.01 ? 40  A   B "C4'" 1 
ATOM 3413 O "O4'" . A   B 2 40  ? 132.612 105.344 76.939  1.00 281.47 ? 40  A   B "O4'" 1 
ATOM 3414 C "C3'" . A   B 2 40  ? 131.793 106.647 78.713  1.00 277.70 ? 40  A   B "C3'" 1 
ATOM 3415 O "O3'" . A   B 2 40  ? 130.840 107.630 79.078  1.00 275.53 ? 40  A   B "O3'" 1 
ATOM 3416 C "C2'" . A   B 2 40  ? 131.302 105.221 78.912  1.00 279.27 ? 40  A   B "C2'" 1 
ATOM 3417 O "O2'" . A   B 2 40  ? 129.960 105.086 78.467  1.00 277.96 ? 40  A   B "O2'" 1 
ATOM 3418 C "C1'" . A   B 2 40  ? 132.208 104.452 77.953  1.00 281.90 ? 40  A   B "C1'" 1 
ATOM 3419 N N9    . A   B 2 40  ? 133.418 103.935 78.621  1.00 283.53 ? 40  A   B N9    1 
ATOM 3420 C C8    . A   B 2 40  ? 134.699 104.415 78.508  1.00 284.03 ? 40  A   B C8    1 
ATOM 3421 N N7    . A   B 2 40  ? 135.579 103.750 79.214  1.00 284.57 ? 40  A   B N7    1 
ATOM 3422 C C5    . A   B 2 40  ? 134.827 102.763 79.835  1.00 284.94 ? 40  A   B C5    1 
ATOM 3423 C C6    . A   B 2 40  ? 135.169 101.727 80.722  1.00 284.64 ? 40  A   B C6    1 
ATOM 3424 N N6    . A   B 2 40  ? 136.412 101.506 81.156  1.00 284.95 ? 40  A   B N6    1 
ATOM 3425 N N1    . A   B 2 40  ? 134.179 100.915 81.155  1.00 284.47 ? 40  A   B N1    1 
ATOM 3426 C C2    . A   B 2 40  ? 132.930 101.133 80.722  1.00 283.91 ? 40  A   B C2    1 
ATOM 3427 N N3    . A   B 2 40  ? 132.485 102.073 79.889  1.00 283.91 ? 40  A   B N3    1 
ATOM 3428 C C4    . A   B 2 40  ? 133.493 102.863 79.477  1.00 284.18 ? 40  A   B C4    1 
ATOM 3429 P P     . A   B 2 41  ? 130.865 108.287 80.544  1.00 272.92 ? 41  A   B P     1 
ATOM 3430 O OP1   . A   B 2 41  ? 129.940 109.448 80.542  1.00 272.45 ? 41  A   B OP1   1 
ATOM 3431 O OP2   . A   B 2 41  ? 132.283 108.485 80.936  1.00 270.09 ? 41  A   B OP2   1 
ATOM 3432 O "O5'" . A   B 2 41  ? 130.238 107.163 81.484  1.00 275.04 ? 41  A   B "O5'" 1 
ATOM 3433 C "C5'" . A   B 2 41  ? 128.904 106.713 81.297  1.00 276.05 ? 41  A   B "C5'" 1 
ATOM 3434 C "C4'" . A   B 2 41  ? 128.645 105.430 82.045  1.00 274.95 ? 41  A   B "C4'" 1 
ATOM 3435 O "O4'" . A   B 2 41  ? 129.565 104.405 81.590  1.00 276.94 ? 41  A   B "O4'" 1 
ATOM 3436 C "C3'" . A   B 2 41  ? 128.864 105.487 83.548  1.00 272.96 ? 41  A   B "C3'" 1 
ATOM 3437 O "O3'" . A   B 2 41  ? 127.752 106.025 84.243  1.00 270.75 ? 41  A   B "O3'" 1 
ATOM 3438 C "C2'" . A   B 2 41  ? 129.162 104.035 83.901  1.00 274.05 ? 41  A   B "C2'" 1 
ATOM 3439 O "O2'" . A   B 2 41  ? 127.961 103.280 83.973  1.00 273.58 ? 41  A   B "O2'" 1 
ATOM 3440 C "C1'" . A   B 2 41  ? 129.944 103.579 82.670  1.00 276.77 ? 41  A   B "C1'" 1 
ATOM 3441 N N9    . A   B 2 41  ? 131.403 103.695 82.857  1.00 277.87 ? 41  A   B N9    1 
ATOM 3442 C C8    . A   B 2 41  ? 132.247 104.625 82.302  1.00 277.17 ? 41  A   B C8    1 
ATOM 3443 N N7    . A   B 2 41  ? 133.502 104.477 82.647  1.00 276.51 ? 41  A   B N7    1 
ATOM 3444 C C5    . A   B 2 41  ? 133.486 103.370 83.483  1.00 277.55 ? 41  A   B C5    1 
ATOM 3445 C C6    . A   B 2 41  ? 134.503 102.697 84.186  1.00 276.96 ? 41  A   B C6    1 
ATOM 3446 N N6    . A   B 2 41  ? 135.788 103.057 84.150  1.00 276.10 ? 41  A   B N6    1 
ATOM 3447 N N1    . A   B 2 41  ? 134.150 101.628 84.935  1.00 277.05 ? 41  A   B N1    1 
ATOM 3448 C C2    . A   B 2 41  ? 132.861 101.264 84.973  1.00 276.50 ? 41  A   B C2    1 
ATOM 3449 N N3    . A   B 2 41  ? 131.817 101.818 84.359  1.00 277.23 ? 41  A   B N3    1 
ATOM 3450 C C4    . A   B 2 41  ? 132.200 102.878 83.623  1.00 277.75 ? 41  A   B C4    1 
ATOM 3451 P P     . A   B 2 42  ? 127.979 106.978 85.515  1.00 265.82 ? 42  A   B P     1 
ATOM 3452 O OP1   . A   B 2 42  ? 126.650 107.453 85.978  1.00 265.84 ? 42  A   B OP1   1 
ATOM 3453 O OP2   . A   B 2 42  ? 129.035 107.964 85.172  1.00 265.68 ? 42  A   B OP2   1 
ATOM 3454 O "O5'" . A   B 2 42  ? 128.565 105.998 86.625  1.00 264.23 ? 42  A   B "O5'" 1 
ATOM 3455 C "C5'" . A   B 2 42  ? 129.593 106.427 87.503  1.00 262.46 ? 42  A   B "C5'" 1 
ATOM 3456 C "C4'" . A   B 2 42  ? 130.870 105.668 87.256  1.00 263.05 ? 42  A   B "C4'" 1 
ATOM 3457 O "O4'" . A   B 2 42  ? 131.280 105.833 85.873  1.00 267.14 ? 42  A   B "O4'" 1 
ATOM 3458 C "C3'" . A   B 2 42  ? 132.080 106.124 88.053  1.00 258.00 ? 42  A   B "C3'" 1 
ATOM 3459 O "O3'" . A   B 2 42  ? 132.097 105.623 89.377  1.00 253.12 ? 42  A   B "O3'" 1 
ATOM 3460 C "C2'" . A   B 2 42  ? 133.238 105.637 87.195  1.00 260.09 ? 42  A   B "C2'" 1 
ATOM 3461 O "O2'" . A   B 2 42  ? 133.434 104.241 87.361  1.00 260.53 ? 42  A   B "O2'" 1 
ATOM 3462 C "C1'" . A   B 2 42  ? 132.690 105.885 85.792  1.00 265.06 ? 42  A   B "C1'" 1 
ATOM 3463 N N9    . A   B 2 42  ? 133.078 107.210 85.269  1.00 262.78 ? 42  A   B N9    1 
ATOM 3464 C C8    . A   B 2 42  ? 132.256 108.293 85.077  1.00 261.94 ? 42  A   B C8    1 
ATOM 3465 N N7    . A   B 2 42  ? 132.869 109.346 84.596  1.00 259.04 ? 42  A   B N7    1 
ATOM 3466 C C5    . A   B 2 42  ? 134.184 108.930 84.460  1.00 257.81 ? 42  A   B C5    1 
ATOM 3467 C C6    . A   B 2 42  ? 135.339 109.588 83.999  1.00 255.81 ? 42  A   B C6    1 
ATOM 3468 N N6    . A   B 2 42  ? 135.342 110.852 83.575  1.00 254.41 ? 42  A   B N6    1 
ATOM 3469 N N1    . A   B 2 42  ? 136.501 108.899 83.985  1.00 255.20 ? 42  A   B N1    1 
ATOM 3470 C C2    . A   B 2 42  ? 136.497 107.627 84.410  1.00 255.66 ? 42  A   B C2    1 
ATOM 3471 N N3    . A   B 2 42  ? 135.474 106.902 84.868  1.00 257.81 ? 42  A   B N3    1 
ATOM 3472 C C4    . A   B 2 42  ? 134.332 107.616 84.867  1.00 259.24 ? 42  A   B C4    1 
ATOM 3473 P P     . G   B 2 43  ? 132.588 106.562 90.585  1.00 248.39 ? 43  G   B P     1 
ATOM 3474 O OP1   . G   B 2 43  ? 131.998 106.046 91.846  1.00 250.55 ? 43  G   B OP1   1 
ATOM 3475 O OP2   . G   B 2 43  ? 132.360 107.973 90.183  1.00 250.00 ? 43  G   B OP2   1 
ATOM 3476 O "O5'" . G   B 2 43  ? 134.161 106.327 90.637  1.00 248.98 ? 43  G   B "O5'" 1 
ATOM 3477 C "C5'" . G   B 2 43  ? 134.701 105.021 90.773  1.00 249.11 ? 43  G   B "C5'" 1 
ATOM 3478 C "C4'" . G   B 2 43  ? 136.190 105.024 90.547  1.00 249.07 ? 43  G   B "C4'" 1 
ATOM 3479 O "O4'" . G   B 2 43  ? 136.471 105.224 89.137  1.00 249.36 ? 43  G   B "O4'" 1 
ATOM 3480 C "C3'" . G   B 2 43  ? 136.953 106.142 91.241  1.00 246.79 ? 43  G   B "C3'" 1 
ATOM 3481 O "O3'" . G   B 2 43  ? 137.236 105.854 92.599  1.00 246.86 ? 43  G   B "O3'" 1 
ATOM 3482 C "C2'" . G   B 2 43  ? 138.191 106.291 90.370  1.00 244.75 ? 43  G   B "C2'" 1 
ATOM 3483 O "O2'" . G   B 2 43  ? 139.128 105.262 90.650  1.00 243.12 ? 43  G   B "O2'" 1 
ATOM 3484 C "C1'" . G   B 2 43  ? 137.607 106.047 88.980  1.00 246.61 ? 43  G   B "C1'" 1 
ATOM 3485 N N9    . G   B 2 43  ? 137.172 107.298 88.331  1.00 245.40 ? 43  G   B N9    1 
ATOM 3486 C C8    . G   B 2 43  ? 135.874 107.639 88.057  1.00 247.94 ? 43  G   B C8    1 
ATOM 3487 N N7    . G   B 2 43  ? 135.740 108.792 87.471  1.00 246.23 ? 43  G   B N7    1 
ATOM 3488 C C5    . G   B 2 43  ? 137.040 109.252 87.350  1.00 243.43 ? 43  G   B C5    1 
ATOM 3489 C C6    . G   B 2 43  ? 137.516 110.462 86.794  1.00 240.99 ? 43  G   B C6    1 
ATOM 3490 O O6    . G   B 2 43  ? 136.857 111.375 86.282  1.00 238.75 ? 43  G   B O6    1 
ATOM 3491 N N1    . G   B 2 43  ? 138.901 110.538 86.867  1.00 240.50 ? 43  G   B N1    1 
ATOM 3492 C C2    . G   B 2 43  ? 139.717 109.575 87.409  1.00 240.82 ? 43  G   B C2    1 
ATOM 3493 N N2    . G   B 2 43  ? 141.030 109.836 87.395  1.00 241.25 ? 43  G   B N2    1 
ATOM 3494 N N3    . G   B 2 43  ? 139.283 108.441 87.935  1.00 242.10 ? 43  G   B N3    1 
ATOM 3495 C C4    . G   B 2 43  ? 137.940 108.342 87.870  1.00 243.26 ? 43  G   B C4    1 
ATOM 3496 P P     . A   B 2 44  ? 137.104 107.004 93.713  1.00 246.56 ? 44  A   B P     1 
ATOM 3497 O OP1   . A   B 2 44  ? 137.013 106.350 95.043  1.00 247.36 ? 44  A   B OP1   1 
ATOM 3498 O OP2   . A   B 2 44  ? 136.038 107.944 93.283  1.00 248.28 ? 44  A   B OP2   1 
ATOM 3499 O "O5'" . A   B 2 44  ? 138.497 107.771 93.632  1.00 242.18 ? 44  A   B "O5'" 1 
ATOM 3500 C "C5'" . A   B 2 44  ? 139.722 107.058 93.704  1.00 241.36 ? 44  A   B "C5'" 1 
ATOM 3501 C "C4'" . A   B 2 44  ? 140.865 107.872 93.155  1.00 240.15 ? 44  A   B "C4'" 1 
ATOM 3502 O "O4'" . A   B 2 44  ? 140.692 108.068 91.728  1.00 241.03 ? 44  A   B "O4'" 1 
ATOM 3503 C "C3'" . A   B 2 44  ? 140.996 109.280 93.709  1.00 237.27 ? 44  A   B "C3'" 1 
ATOM 3504 O "O3'" . A   B 2 44  ? 141.645 109.315 94.966  1.00 240.24 ? 44  A   B "O3'" 1 
ATOM 3505 C "C2'" . A   B 2 44  ? 141.758 110.000 92.605  1.00 234.64 ? 44  A   B "C2'" 1 
ATOM 3506 O "O2'" . A   B 2 44  ? 143.141 109.683 92.663  1.00 235.53 ? 44  A   B "O2'" 1 
ATOM 3507 C "C1'" . A   B 2 44  ? 141.166 109.346 91.357  1.00 237.33 ? 44  A   B "C1'" 1 
ATOM 3508 N N9    . A   B 2 44  ? 140.037 110.114 90.796  1.00 235.05 ? 44  A   B N9    1 
ATOM 3509 C C8    . A   B 2 44  ? 138.723 109.723 90.759  1.00 236.61 ? 44  A   B C8    1 
ATOM 3510 N N7    . A   B 2 44  ? 137.921 110.585 90.190  1.00 233.13 ? 44  A   B N7    1 
ATOM 3511 C C5    . A   B 2 44  ? 138.763 111.626 89.833  1.00 229.26 ? 44  A   B C5    1 
ATOM 3512 C C6    . A   B 2 44  ? 138.521 112.849 89.189  1.00 225.66 ? 44  A   B C6    1 
ATOM 3513 N N6    . A   B 2 44  ? 137.310 113.237 88.786  1.00 220.77 ? 44  A   B N6    1 
ATOM 3514 N N1    . A   B 2 44  ? 139.572 113.670 88.972  1.00 225.44 ? 44  A   B N1    1 
ATOM 3515 C C2    . A   B 2 44  ? 140.791 113.275 89.371  1.00 225.41 ? 44  A   B C2    1 
ATOM 3516 N N3    . A   B 2 44  ? 141.141 112.146 89.991  1.00 228.43 ? 44  A   B N3    1 
ATOM 3517 C C4    . A   B 2 44  ? 140.072 111.352 90.193  1.00 230.91 ? 44  A   B C4    1 
ATOM 3518 P P     . G   B 2 45  ? 141.085 110.262 96.135  1.00 240.79 ? 45  G   B P     1 
ATOM 3519 O OP1   . G   B 2 45  ? 141.557 109.719 97.434  1.00 241.38 ? 45  G   B OP1   1 
ATOM 3520 O OP2   . G   B 2 45  ? 139.632 110.464 95.904  1.00 239.26 ? 45  G   B OP2   1 
ATOM 3521 O "O5'" . G   B 2 45  ? 141.821 111.651 95.882  1.00 230.82 ? 45  G   B "O5'" 1 
ATOM 3522 C "C5'" . G   B 2 45  ? 143.232 111.709 95.749  1.00 229.86 ? 45  G   B "C5'" 1 
ATOM 3523 C "C4'" . G   B 2 45  ? 143.665 112.958 95.026  1.00 226.67 ? 45  G   B "C4'" 1 
ATOM 3524 O "O4'" . G   B 2 45  ? 143.220 112.909 93.646  1.00 225.84 ? 45  G   B "O4'" 1 
ATOM 3525 C "C3'" . G   B 2 45  ? 143.090 114.263 95.550  1.00 221.16 ? 45  G   B "C3'" 1 
ATOM 3526 O "O3'" . G   B 2 45  ? 143.763 114.749 96.698  1.00 224.24 ? 45  G   B "O3'" 1 
ATOM 3527 C "C2'" . G   B 2 45  ? 143.201 115.182 94.343  1.00 217.62 ? 45  G   B "C2'" 1 
ATOM 3528 O "O2'" . G   B 2 45  ? 144.533 115.652 94.192  1.00 218.20 ? 45  G   B "O2'" 1 
ATOM 3529 C "C1'" . G   B 2 45  ? 142.902 114.211 93.199  1.00 219.85 ? 45  G   B "C1'" 1 
ATOM 3530 N N9    . G   B 2 45  ? 141.483 114.242 92.793  1.00 217.16 ? 45  G   B N9    1 
ATOM 3531 C C8    . G   B 2 45  ? 140.552 113.244 92.940  1.00 219.57 ? 45  G   B C8    1 
ATOM 3532 N N7    . G   B 2 45  ? 139.376 113.557 92.470  1.00 216.06 ? 45  G   B N7    1 
ATOM 3533 C C5    . G   B 2 45  ? 139.535 114.848 91.988  1.00 211.12 ? 45  G   B C5    1 
ATOM 3534 C C6    . G   B 2 45  ? 138.607 115.713 91.357  1.00 205.79 ? 45  G   B C6    1 
ATOM 3535 O O6    . G   B 2 45  ? 137.416 115.504 91.101  1.00 202.36 ? 45  G   B O6    1 
ATOM 3536 N N1    . G   B 2 45  ? 139.188 116.931 91.021  1.00 203.39 ? 45  G   B N1    1 
ATOM 3537 C C2    . G   B 2 45  ? 140.496 117.267 91.258  1.00 203.74 ? 45  G   B C2    1 
ATOM 3538 N N2    . G   B 2 45  ? 140.886 118.486 90.867  1.00 201.74 ? 45  G   B N2    1 
ATOM 3539 N N3    . G   B 2 45  ? 141.373 116.468 91.838  1.00 206.90 ? 45  G   B N3    1 
ATOM 3540 C C4    . G   B 2 45  ? 140.831 115.280 92.171  1.00 211.18 ? 45  G   B C4    1 
ATOM 3541 P P     . C   B 2 46  ? 142.959 115.598 97.800  1.00 224.79 ? 46  C   B P     1 
ATOM 3542 O OP1   . C   B 2 46  ? 143.809 115.709 99.012  1.00 225.42 ? 46  C   B OP1   1 
ATOM 3543 O OP2   . C   B 2 46  ? 141.592 115.029 97.907  1.00 219.17 ? 46  C   B OP2   1 
ATOM 3544 O "O5'" . C   B 2 46  ? 142.830 117.047 97.152  1.00 213.60 ? 46  C   B "O5'" 1 
ATOM 3545 C "C5'" . C   B 2 46  ? 143.966 117.883 96.989  1.00 209.59 ? 46  C   B "C5'" 1 
ATOM 3546 C "C4'" . C   B 2 46  ? 143.612 119.141 96.238  1.00 203.90 ? 46  C   B "C4'" 1 
ATOM 3547 O "O4'" . C   B 2 46  ? 143.042 118.789 94.950  1.00 201.90 ? 46  C   B "O4'" 1 
ATOM 3548 C "C3'" . C   B 2 46  ? 142.552 120.019 96.885  1.00 197.24 ? 46  C   B "C3'" 1 
ATOM 3549 O "O3'" . C   B 2 46  ? 143.078 120.872 97.887  1.00 199.67 ? 46  C   B "O3'" 1 
ATOM 3550 C "C2'" . C   B 2 46  ? 141.964 120.769 95.699  1.00 190.47 ? 46  C   B "C2'" 1 
ATOM 3551 O "O2'" . C   B 2 46  ? 142.805 121.849 95.323  1.00 188.04 ? 46  C   B "O2'" 1 
ATOM 3552 C "C1'" . C   B 2 46  ? 142.026 119.706 94.601  1.00 195.19 ? 46  C   B "C1'" 1 
ATOM 3553 N N1    . C   B 2 46  ? 140.752 118.963 94.437  1.00 193.70 ? 46  C   B N1    1 
ATOM 3554 C C2    . C   B 2 46  ? 139.664 119.555 93.778  1.00 185.73 ? 46  C   B C2    1 
ATOM 3555 O O2    . C   B 2 46  ? 139.767 120.713 93.347  1.00 182.27 ? 46  C   B O2    1 
ATOM 3556 N N3    . C   B 2 46  ? 138.518 118.849 93.630  1.00 184.90 ? 46  C   B N3    1 
ATOM 3557 C C4    . C   B 2 46  ? 138.430 117.605 94.100  1.00 189.58 ? 46  C   B C4    1 
ATOM 3558 N N4    . C   B 2 46  ? 137.282 116.946 93.933  1.00 187.47 ? 46  C   B N4    1 
ATOM 3559 C C5    . C   B 2 46  ? 139.517 116.974 94.765  1.00 198.55 ? 46  C   B C5    1 
ATOM 3560 C C6    . C   B 2 46  ? 140.643 117.681 94.902  1.00 200.03 ? 46  C   B C6    1 
ATOM 3561 P P     . C   B 2 47  ? 142.154 121.349 99.112  1.00 203.17 ? 47  C   B P     1 
ATOM 3562 O OP1   . C   B 2 47  ? 143.012 122.104 100.059 1.00 199.94 ? 47  C   B OP1   1 
ATOM 3563 O OP2   . C   B 2 47  ? 141.382 120.176 99.593  1.00 200.55 ? 47  C   B OP2   1 
ATOM 3564 O "O5'" . C   B 2 47  ? 141.129 122.376 98.453  1.00 188.34 ? 47  C   B "O5'" 1 
ATOM 3565 C "C5'" . C   B 2 47  ? 141.551 123.665 98.034  1.00 181.46 ? 47  C   B "C5'" 1 
ATOM 3566 C "C4'" . C   B 2 47  ? 140.444 124.403 97.325  1.00 175.19 ? 47  C   B "C4'" 1 
ATOM 3567 O "O4'" . C   B 2 47  ? 139.981 123.619 96.194  1.00 172.88 ? 47  C   B "O4'" 1 
ATOM 3568 C "C3'" . C   B 2 47  ? 139.184 124.651 98.140  1.00 167.05 ? 47  C   B "C3'" 1 
ATOM 3569 O "O3'" . C   B 2 47  ? 139.289 125.771 99.000  1.00 166.65 ? 47  C   B "O3'" 1 
ATOM 3570 C "C2'" . C   B 2 47  ? 138.115 124.806 97.067  1.00 158.48 ? 47  C   B "C2'" 1 
ATOM 3571 O "O2'" . C   B 2 47  ? 138.155 126.108 96.503  1.00 154.46 ? 47  C   B "O2'" 1 
ATOM 3572 C "C1'" . C   B 2 47  ? 138.593 123.805 96.012  1.00 164.51 ? 47  C   B "C1'" 1 
ATOM 3573 N N1    . C   B 2 47  ? 137.913 122.492 96.125  1.00 165.77 ? 47  C   B N1    1 
ATOM 3574 C C2    . C   B 2 47  ? 136.621 122.337 95.606  1.00 159.42 ? 47  C   B C2    1 
ATOM 3575 O O2    . C   B 2 47  ? 136.050 123.295 95.065  1.00 156.24 ? 47  C   B O2    1 
ATOM 3576 N N3    . C   B 2 47  ? 136.000 121.139 95.704  1.00 158.42 ? 47  C   B N3    1 
ATOM 3577 C C4    . C   B 2 47  ? 136.623 120.114 96.285  1.00 162.18 ? 47  C   B C4    1 
ATOM 3578 N N4    . C   B 2 47  ? 135.980 118.948 96.361  1.00 160.25 ? 47  C   B N4    1 
ATOM 3579 C C5    . C   B 2 47  ? 137.937 120.234 96.819  1.00 171.15 ? 47  C   B C5    1 
ATOM 3580 C C6    . C   B 2 47  ? 138.536 121.426 96.715  1.00 172.47 ? 47  C   B C6    1 
ATOM 3581 P P     . U   B 2 48  ? 138.474 125.797 100.383 1.00 163.05 ? 48  U   B P     1 
ATOM 3582 O OP1   . U   B 2 48  ? 138.980 126.931 101.198 1.00 164.18 ? 48  U   B OP1   1 
ATOM 3583 O OP2   . U   B 2 48  ? 138.493 124.421 100.942 1.00 161.07 ? 48  U   B OP2   1 
ATOM 3584 O "O5'" . U   B 2 48  ? 136.979 126.131 99.945  1.00 147.20 ? 48  U   B "O5'" 1 
ATOM 3585 C "C5'" . U   B 2 48  ? 136.656 127.378 99.350  1.00 142.15 ? 48  U   B "C5'" 1 
ATOM 3586 C "C4'" . U   B 2 48  ? 135.201 127.444 98.957  1.00 135.40 ? 48  U   B "C4'" 1 
ATOM 3587 O "O4'" . U   B 2 48  ? 134.920 126.440 97.949  1.00 136.23 ? 48  U   B "O4'" 1 
ATOM 3588 C "C3'" . U   B 2 48  ? 134.201 127.151 100.064 1.00 126.32 ? 48  U   B "C3'" 1 
ATOM 3589 O "O3'" . U   B 2 48  ? 133.945 128.282 100.877 1.00 122.57 ? 48  U   B "O3'" 1 
ATOM 3590 C "C2'" . U   B 2 48  ? 132.975 126.674 99.297  1.00 120.57 ? 48  U   B "C2'" 1 
ATOM 3591 O "O2'" . U   B 2 48  ? 132.247 127.779 98.784  1.00 116.91 ? 48  U   B "O2'" 1 
ATOM 3592 C "C1'" . U   B 2 48  ? 133.614 125.934 98.121  1.00 127.79 ? 48  U   B "C1'" 1 
ATOM 3593 N N1    . U   B 2 48  ? 133.701 124.469 98.324  1.00 130.34 ? 48  U   B N1    1 
ATOM 3594 C C2    . U   B 2 48  ? 132.557 123.695 98.227  1.00 126.64 ? 48  U   B C2    1 
ATOM 3595 O O2    . U   B 2 48  ? 131.448 124.147 98.003  1.00 122.19 ? 48  U   B O2    1 
ATOM 3596 N N3    . U   B 2 48  ? 132.751 122.348 98.410  1.00 131.21 ? 48  U   B N3    1 
ATOM 3597 C C4    . U   B 2 48  ? 133.946 121.705 98.665  1.00 136.13 ? 48  U   B C4    1 
ATOM 3598 O O4    . U   B 2 48  ? 133.973 120.483 98.808  1.00 134.74 ? 48  U   B O4    1 
ATOM 3599 C C5    . U   B 2 48  ? 135.080 122.569 98.739  1.00 142.21 ? 48  U   B C5    1 
ATOM 3600 C C6    . U   B 2 48  ? 134.920 123.882 98.565  1.00 140.37 ? 48  U   B C6    1 
ATOM 3601 P P     . U   B 2 49  ? 133.573 128.102 102.428 1.00 121.42 ? 49  U   B P     1 
ATOM 3602 O OP1   . U   B 2 49  ? 133.571 129.451 103.043 1.00 115.46 ? 49  U   B OP1   1 
ATOM 3603 O OP2   . U   B 2 49  ? 134.430 127.028 102.991 1.00 120.78 ? 49  U   B OP2   1 
ATOM 3604 O "O5'" . U   B 2 49  ? 132.070 127.577 102.412 1.00 112.78 ? 49  U   B "O5'" 1 
ATOM 3605 C "C5'" . U   B 2 49  ? 131.007 128.424 102.002 1.00 106.12 ? 49  U   B "C5'" 1 
ATOM 3606 C "C4'" . U   B 2 49  ? 129.707 127.669 101.910 1.00 102.09 ? 49  U   B "C4'" 1 
ATOM 3607 O "O4'" . U   B 2 49  ? 129.843 126.581 100.959 1.00 106.45 ? 49  U   B "O4'" 1 
ATOM 3608 C "C3'" . U   B 2 49  ? 129.243 126.983 103.185 1.00 96.86  ? 49  U   B "C3'" 1 
ATOM 3609 O "O3'" . U   B 2 49  ? 128.602 127.863 104.091 1.00 97.63  ? 49  U   B "O3'" 1 
ATOM 3610 C "C2'" . U   B 2 49  ? 128.335 125.884 102.655 1.00 96.18  ? 49  U   B "C2'" 1 
ATOM 3611 O "O2'" . U   B 2 49  ? 127.070 126.414 102.295 1.00 97.61  ? 49  U   B "O2'" 1 
ATOM 3612 C "C1'" . U   B 2 49  ? 129.066 125.478 101.375 1.00 100.90 ? 49  U   B "C1'" 1 
ATOM 3613 N N1    . U   B 2 49  ? 129.957 124.309 101.574 1.00 101.68 ? 49  U   B N1    1 
ATOM 3614 C C2    . U   B 2 49  ? 129.388 123.050 101.554 1.00 100.17 ? 49  U   B C2    1 
ATOM 3615 O O2    . U   B 2 49  ? 128.197 122.862 101.391 1.00 99.21  ? 49  U   B O2    1 
ATOM 3616 N N3    . U   B 2 49  ? 130.260 122.006 101.741 1.00 102.93 ? 49  U   B N3    1 
ATOM 3617 C C4    . U   B 2 49  ? 131.623 122.092 101.935 1.00 104.50 ? 49  U   B C4    1 
ATOM 3618 O O4    . U   B 2 49  ? 132.291 121.070 102.088 1.00 105.64 ? 49  U   B O4    1 
ATOM 3619 C C5    . U   B 2 49  ? 132.138 123.423 101.937 1.00 107.04 ? 49  U   B C5    1 
ATOM 3620 C C6    . U   B 2 49  ? 131.311 124.454 101.758 1.00 106.65 ? 49  U   B C6    1 
ATOM 3621 P P     . A   B 2 50  ? 128.763 127.647 105.675 1.00 99.80  ? 50  A   B P     1 
ATOM 3622 O OP1   . A   B 2 50  ? 128.153 128.814 106.361 1.00 90.56  ? 50  A   B OP1   1 
ATOM 3623 O OP2   . A   B 2 50  ? 130.172 127.280 105.957 1.00 96.04  ? 50  A   B OP2   1 
ATOM 3624 O "O5'" . A   B 2 50  ? 127.855 126.378 105.987 1.00 94.72  ? 50  A   B "O5'" 1 
ATOM 3625 C "C5'" . A   B 2 50  ? 126.440 126.475 105.950 1.00 88.24  ? 50  A   B "C5'" 1 
ATOM 3626 C "C4'" . A   B 2 50  ? 125.787 125.116 105.950 1.00 84.91  ? 50  A   B "C4'" 1 
ATOM 3627 O "O4'" . A   B 2 50  ? 126.276 124.332 104.834 1.00 86.09  ? 50  A   B "O4'" 1 
ATOM 3628 C "C3'" . A   B 2 50  ? 126.055 124.238 107.159 1.00 79.49  ? 50  A   B "C3'" 1 
ATOM 3629 O "O3'" . A   B 2 50  ? 125.243 124.578 108.270 1.00 80.72  ? 50  A   B "O3'" 1 
ATOM 3630 C "C2'" . A   B 2 50  ? 125.784 122.841 106.617 1.00 78.69  ? 50  A   B "C2'" 1 
ATOM 3631 O "O2'" . A   B 2 50  ? 124.389 122.585 106.577 1.00 81.75  ? 50  A   B "O2'" 1 
ATOM 3632 C "C1'" . A   B 2 50  ? 126.290 122.964 105.180 1.00 80.22  ? 50  A   B "C1'" 1 
ATOM 3633 N N9    . A   B 2 50  ? 127.658 122.439 105.012 1.00 77.42  ? 50  A   B N9    1 
ATOM 3634 C C8    . A   B 2 50  ? 128.810 123.151 104.816 1.00 84.17  ? 50  A   B C8    1 
ATOM 3635 N N7    . A   B 2 50  ? 129.881 122.408 104.689 1.00 86.74  ? 50  A   B N7    1 
ATOM 3636 C C5    . A   B 2 50  ? 129.402 121.114 104.812 1.00 84.46  ? 50  A   B C5    1 
ATOM 3637 C C6    . A   B 2 50  ? 130.035 119.859 104.774 1.00 85.23  ? 50  A   B C6    1 
ATOM 3638 N N6    . A   B 2 50  ? 131.347 119.705 104.594 1.00 87.71  ? 50  A   B N6    1 
ATOM 3639 N N1    . A   B 2 50  ? 129.272 118.753 104.929 1.00 83.08  ? 50  A   B N1    1 
ATOM 3640 C C2    . A   B 2 50  ? 127.954 118.912 105.104 1.00 84.29  ? 50  A   B C2    1 
ATOM 3641 N N3    . A   B 2 50  ? 127.246 120.040 105.162 1.00 83.62  ? 50  A   B N3    1 
ATOM 3642 C C4    . A   B 2 50  ? 128.034 121.118 105.004 1.00 80.07  ? 50  A   B C4    1 
ATOM 3643 P P     . A   B 2 51  ? 125.751 124.311 109.772 1.00 73.76  ? 51  A   B P     1 
ATOM 3644 O OP1   . A   B 2 51  ? 124.810 124.990 110.696 1.00 78.15  ? 51  A   B OP1   1 
ATOM 3645 O OP2   . A   B 2 51  ? 127.198 124.623 109.849 1.00 77.52  ? 51  A   B OP2   1 
ATOM 3646 O "O5'" . A   B 2 51  ? 125.578 122.740 109.966 1.00 72.81  ? 51  A   B "O5'" 1 
ATOM 3647 C "C5'" . A   B 2 51  ? 124.293 122.141 109.925 1.00 76.67  ? 51  A   B "C5'" 1 
ATOM 3648 C "C4'" . A   B 2 51  ? 124.384 120.638 109.870 1.00 72.68  ? 51  A   B "C4'" 1 
ATOM 3649 O "O4'" . A   B 2 51  ? 125.060 120.226 108.658 1.00 70.81  ? 51  A   B "O4'" 1 
ATOM 3650 C "C3'" . A   B 2 51  ? 125.186 119.982 110.978 1.00 71.53  ? 51  A   B "C3'" 1 
ATOM 3651 O "O3'" . A   B 2 51  ? 124.444 119.842 112.173 1.00 75.12  ? 51  A   B "O3'" 1 
ATOM 3652 C "C2'" . A   B 2 51  ? 125.593 118.654 110.356 1.00 68.99  ? 51  A   B "C2'" 1 
ATOM 3653 O "O2'" . A   B 2 51  ? 124.520 117.727 110.415 1.00 69.48  ? 51  A   B "O2'" 1 
ATOM 3654 C "C1'" . A   B 2 51  ? 125.802 119.049 108.897 1.00 68.04  ? 51  A   B "C1'" 1 
ATOM 3655 N N9    . A   B 2 51  ? 127.215 119.306 108.568 1.00 69.20  ? 51  A   B N9    1 
ATOM 3656 C C8    . A   B 2 51  ? 127.766 120.515 108.249 1.00 73.27  ? 51  A   B C8    1 
ATOM 3657 N N7    . A   B 2 51  ? 129.041 120.470 107.969 1.00 74.94  ? 51  A   B N7    1 
ATOM 3658 C C5    . A   B 2 51  ? 129.353 119.133 108.120 1.00 71.43  ? 51  A   B C5    1 
ATOM 3659 C C6    . A   B 2 51  ? 130.556 118.434 107.963 1.00 74.18  ? 51  A   B C6    1 
ATOM 3660 N N6    . A   B 2 51  ? 131.702 119.021 107.618 1.00 78.81  ? 51  A   B N6    1 
ATOM 3661 N N1    . A   B 2 51  ? 130.543 117.103 108.184 1.00 73.39  ? 51  A   B N1    1 
ATOM 3662 C C2    . A   B 2 51  ? 129.390 116.517 108.531 1.00 72.21  ? 51  A   B C2    1 
ATOM 3663 N N3    . A   B 2 51  ? 128.191 117.073 108.705 1.00 71.55  ? 51  A   B N3    1 
ATOM 3664 C C4    . A   B 2 51  ? 128.240 118.397 108.480 1.00 69.61  ? 51  A   B C4    1 
ATOM 3665 P P     . U   B 2 52  ? 125.160 120.038 113.594 1.00 69.32  ? 52  U   B P     1 
ATOM 3666 O OP1   . U   B 2 52  ? 124.099 119.983 114.627 1.00 75.15  ? 52  U   B OP1   1 
ATOM 3667 O OP2   . U   B 2 52  ? 126.046 121.226 113.513 1.00 73.49  ? 52  U   B OP2   1 
ATOM 3668 O "O5'" . U   B 2 52  ? 126.053 118.730 113.752 1.00 65.00  ? 52  U   B "O5'" 1 
ATOM 3669 C "C5'" . U   B 2 52  ? 125.441 117.452 113.798 1.00 66.58  ? 52  U   B "C5'" 1 
ATOM 3670 C "C4'" . U   B 2 52  ? 126.440 116.339 113.620 1.00 64.49  ? 52  U   B "C4'" 1 
ATOM 3671 O "O4'" . U   B 2 52  ? 127.081 116.425 112.322 1.00 62.12  ? 52  U   B "O4'" 1 
ATOM 3672 C "C3'" . U   B 2 52  ? 127.603 116.321 114.590 1.00 66.42  ? 52  U   B "C3'" 1 
ATOM 3673 O "O3'" . U   B 2 52  ? 127.257 115.818 115.866 1.00 72.60  ? 52  U   B "O3'" 1 
ATOM 3674 C "C2'" . U   B 2 52  ? 128.625 115.470 113.851 1.00 60.72  ? 52  U   B "C2'" 1 
ATOM 3675 O "O2'" . U   B 2 52  ? 128.289 114.095 113.945 1.00 62.09  ? 52  U   B "O2'" 1 
ATOM 3676 C "C1'" . U   B 2 52  ? 128.399 115.919 112.408 1.00 59.07  ? 52  U   B "C1'" 1 
ATOM 3677 N N1    . U   B 2 52  ? 129.346 116.978 111.989 1.00 62.32  ? 52  U   B N1    1 
ATOM 3678 C C2    . U   B 2 52  ? 130.667 116.652 111.723 1.00 64.92  ? 52  U   B C2    1 
ATOM 3679 O O2    . U   B 2 52  ? 131.126 115.527 111.824 1.00 66.57  ? 52  U   B O2    1 
ATOM 3680 N N3    . U   B 2 52  ? 131.456 117.707 111.337 1.00 64.59  ? 52  U   B N3    1 
ATOM 3681 C C4    . U   B 2 52  ? 131.069 119.021 111.185 1.00 64.76  ? 52  U   B C4    1 
ATOM 3682 O O4    . U   B 2 52  ? 131.893 119.859 110.825 1.00 66.21  ? 52  U   B O4    1 
ATOM 3683 C C5    . U   B 2 52  ? 129.695 119.276 111.469 1.00 66.14  ? 52  U   B C5    1 
ATOM 3684 C C6    . U   B 2 52  ? 128.907 118.270 111.847 1.00 66.03  ? 52  U   B C6    1 
ATOM 3685 P P     . U   B 2 53  ? 128.040 116.340 117.166 1.00 69.29  ? 53  U   B P     1 
ATOM 3686 O OP1   . U   B 2 53  ? 127.295 115.911 118.375 1.00 71.48  ? 53  U   B OP1   1 
ATOM 3687 O OP2   . U   B 2 53  ? 128.327 117.781 116.959 1.00 65.78  ? 53  U   B OP2   1 
ATOM 3688 O "O5'" . U   B 2 53  ? 129.420 115.545 117.120 1.00 60.15  ? 53  U   B "O5'" 1 
ATOM 3689 C "C5'" . U   B 2 53  ? 129.442 114.126 117.152 1.00 56.12  ? 53  U   B "C5'" 1 
ATOM 3690 C "C4'" . U   B 2 53  ? 130.835 113.584 116.953 1.00 54.35  ? 53  U   B "C4'" 1 
ATOM 3691 O "O4'" . U   B 2 53  ? 131.307 113.897 115.618 1.00 54.94  ? 53  U   B "O4'" 1 
ATOM 3692 C "C3'" . U   B 2 53  ? 131.909 114.157 117.860 1.00 55.69  ? 53  U   B "C3'" 1 
ATOM 3693 O "O3'" . U   B 2 53  ? 131.910 113.585 119.154 1.00 53.69  ? 53  U   B "O3'" 1 
ATOM 3694 C "C2'" . U   B 2 53  ? 133.183 113.886 117.072 1.00 53.26  ? 53  U   B "C2'" 1 
ATOM 3695 O "O2'" . U   B 2 53  ? 133.581 112.532 117.210 1.00 52.15  ? 53  U   B "O2'" 1 
ATOM 3696 C "C1'" . U   B 2 53  ? 132.705 114.101 115.639 1.00 51.68  ? 53  U   B "C1'" 1 
ATOM 3697 N N1    . U   B 2 53  ? 133.000 115.464 115.140 1.00 53.04  ? 53  U   B N1    1 
ATOM 3698 C C2    . U   B 2 53  ? 134.296 115.762 114.757 1.00 56.31  ? 53  U   B C2    1 
ATOM 3699 O O2    . U   B 2 53  ? 135.211 114.962 114.818 1.00 58.02  ? 53  U   B O2    1 
ATOM 3700 N N3    . U   B 2 53  ? 134.489 117.043 114.300 1.00 57.79  ? 53  U   B N3    1 
ATOM 3701 C C4    . U   B 2 53  ? 133.542 118.034 114.182 1.00 59.01  ? 53  U   B C4    1 
ATOM 3702 O O4    . U   B 2 53  ? 133.855 119.146 113.752 1.00 63.62  ? 53  U   B O4    1 
ATOM 3703 C C5    . U   B 2 53  ? 132.234 117.645 114.595 1.00 57.35  ? 53  U   B C5    1 
ATOM 3704 C C6    . U   B 2 53  ? 132.011 116.409 115.044 1.00 56.32  ? 53  U   B C6    1 
ATOM 3705 P P     . G   B 2 54  ? 132.466 114.424 120.405 1.00 51.01  ? 54  G   B P     1 
ATOM 3706 O OP1   . G   B 2 54  ? 132.179 113.625 121.620 1.00 56.04  ? 54  G   B OP1   1 
ATOM 3707 O OP2   . G   B 2 54  ? 131.985 115.825 120.307 1.00 48.22  ? 54  G   B OP2   1 
ATOM 3708 O "O5'" . G   B 2 54  ? 134.043 114.418 120.200 1.00 49.34  ? 54  G   B "O5'" 1 
ATOM 3709 C "C5'" . G   B 2 54  ? 134.775 113.208 120.301 1.00 51.10  ? 54  G   B "C5'" 1 
ATOM 3710 C "C4'" . G   B 2 54  ? 136.218 113.400 119.915 1.00 48.08  ? 54  G   B "C4'" 1 
ATOM 3711 O "O4'" . G   B 2 54  ? 136.308 113.801 118.526 1.00 45.46  ? 54  G   B "O4'" 1 
ATOM 3712 C "C3'" . G   B 2 54  ? 136.963 114.494 120.655 1.00 48.91  ? 54  G   B "C3'" 1 
ATOM 3713 O "O3'" . G   B 2 54  ? 137.400 114.095 121.940 1.00 48.70  ? 54  G   B "O3'" 1 
ATOM 3714 C "C2'" . G   B 2 54  ? 138.100 114.822 119.700 1.00 49.65  ? 54  G   B "C2'" 1 
ATOM 3715 O "O2'" . G   B 2 54  ? 139.119 113.838 119.787 1.00 51.49  ? 54  G   B "O2'" 1 
ATOM 3716 C "C1'" . G   B 2 54  ? 137.408 114.668 118.348 1.00 47.64  ? 54  G   B "C1'" 1 
ATOM 3717 N N9    . G   B 2 54  ? 136.923 115.949 117.802 1.00 49.44  ? 54  G   B N9    1 
ATOM 3718 C C8    . G   B 2 54  ? 135.633 116.411 117.781 1.00 51.38  ? 54  G   B C8    1 
ATOM 3719 N N7    . G   B 2 54  ? 135.517 117.577 117.207 1.00 51.21  ? 54  G   B N7    1 
ATOM 3720 C C5    . G   B 2 54  ? 136.808 117.905 116.823 1.00 50.34  ? 54  G   B C5    1 
ATOM 3721 C C6    . G   B 2 54  ? 137.308 119.055 116.161 1.00 52.37  ? 54  G   B C6    1 
ATOM 3722 O O6    . G   B 2 54  ? 136.683 120.043 115.759 1.00 52.56  ? 54  G   B O6    1 
ATOM 3723 N N1    . G   B 2 54  ? 138.683 118.976 115.968 1.00 53.88  ? 54  G   B N1    1 
ATOM 3724 C C2    . G   B 2 54  ? 139.469 117.926 116.371 1.00 54.07  ? 54  G   B C2    1 
ATOM 3725 N N2    . G   B 2 54  ? 140.777 118.017 116.107 1.00 55.52  ? 54  G   B N2    1 
ATOM 3726 N N3    . G   B 2 54  ? 139.015 116.854 116.990 1.00 52.09  ? 54  G   B N3    1 
ATOM 3727 C C4    . G   B 2 54  ? 137.685 116.909 117.183 1.00 49.58  ? 54  G   B C4    1 
ATOM 3728 P P     . U   B 2 55  ? 137.426 115.161 123.136 1.00 43.52  ? 55  U   B P     1 
ATOM 3729 O OP1   . U   B 2 55  ? 137.662 114.420 124.395 1.00 46.82  ? 55  U   B OP1   1 
ATOM 3730 O OP2   . U   B 2 55  ? 136.236 116.037 123.004 1.00 39.48  ? 55  U   B OP2   1 
ATOM 3731 O "O5'" . U   B 2 55  ? 138.717 116.041 122.836 1.00 42.85  ? 55  U   B "O5'" 1 
ATOM 3732 C "C5'" . U   B 2 55  ? 140.016 115.508 123.031 1.00 40.79  ? 55  U   B "C5'" 1 
ATOM 3733 C "C4'" . U   B 2 55  ? 141.072 116.377 122.398 1.00 43.78  ? 55  U   B "C4'" 1 
ATOM 3734 O "O4'" . U   B 2 55  ? 140.744 116.608 121.003 1.00 42.96  ? 55  U   B "O4'" 1 
ATOM 3735 C "C3'" . U   B 2 55  ? 141.222 117.778 122.964 1.00 45.32  ? 55  U   B "C3'" 1 
ATOM 3736 O "O3'" . U   B 2 55  ? 141.947 117.833 124.178 1.00 47.83  ? 55  U   B "O3'" 1 
ATOM 3737 C "C2'" . U   B 2 55  ? 141.894 118.514 121.818 1.00 45.97  ? 55  U   B "C2'" 1 
ATOM 3738 O "O2'" . U   B 2 55  ? 143.272 118.180 121.752 1.00 49.48  ? 55  U   B "O2'" 1 
ATOM 3739 C "C1'" . U   B 2 55  ? 141.194 117.889 120.613 1.00 43.69  ? 55  U   B "C1'" 1 
ATOM 3740 N N1    . U   B 2 55  ? 140.038 118.699 120.167 1.00 43.44  ? 55  U   B N1    1 
ATOM 3741 C C2    . U   B 2 55  ? 140.306 119.787 119.360 1.00 46.87  ? 55  U   B C2    1 
ATOM 3742 O O2    . U   B 2 55  ? 141.430 120.090 119.005 1.00 48.52  ? 55  U   B O2    1 
ATOM 3743 N N3    . U   B 2 55  ? 139.214 120.518 118.971 1.00 48.45  ? 55  U   B N3    1 
ATOM 3744 C C4    . U   B 2 55  ? 137.901 120.272 119.306 1.00 48.71  ? 55  U   B C4    1 
ATOM 3745 O O4    . U   B 2 55  ? 137.009 121.007 118.886 1.00 53.05  ? 55  U   B O4    1 
ATOM 3746 C C5    . U   B 2 55  ? 137.703 119.134 120.145 1.00 48.67  ? 55  U   B C5    1 
ATOM 3747 C C6    . U   B 2 55  ? 138.749 118.406 120.534 1.00 47.44  ? 55  U   B C6    1 
ATOM 3748 P P     . A   B 2 56  ? 141.599 118.964 125.265 1.00 52.80  ? 56  A   B P     1 
ATOM 3749 O OP1   . A   B 2 56  ? 142.401 118.687 126.481 1.00 50.25  ? 56  A   B OP1   1 
ATOM 3750 O OP2   . A   B 2 56  ? 140.124 119.082 125.357 1.00 42.32  ? 56  A   B OP2   1 
ATOM 3751 O "O5'" . A   B 2 56  ? 142.125 120.316 124.610 1.00 50.99  ? 56  A   B "O5'" 1 
ATOM 3752 C "C5'" . A   B 2 56  ? 143.513 120.559 124.447 1.00 45.95  ? 56  A   B "C5'" 1 
ATOM 3753 C "C4'" . A   B 2 56  ? 143.764 121.738 123.543 1.00 45.88  ? 56  A   B "C4'" 1 
ATOM 3754 O "O4'" . A   B 2 56  ? 143.047 121.560 122.297 1.00 46.42  ? 56  A   B "O4'" 1 
ATOM 3755 C "C3'" . A   B 2 56  ? 143.283 123.087 124.051 1.00 49.15  ? 56  A   B "C3'" 1 
ATOM 3756 O "O3'" . A   B 2 56  ? 144.182 123.678 124.968 1.00 52.55  ? 56  A   B "O3'" 1 
ATOM 3757 C "C2'" . A   B 2 56  ? 143.122 123.886 122.767 1.00 48.82  ? 56  A   B "C2'" 1 
ATOM 3758 O "O2'" . A   B 2 56  ? 144.381 124.355 122.311 1.00 55.28  ? 56  A   B "O2'" 1 
ATOM 3759 C "C1'" . A   B 2 56  ? 142.633 122.812 121.799 1.00 46.81  ? 56  A   B "C1'" 1 
ATOM 3760 N N9    . A   B 2 56  ? 141.167 122.811 121.654 1.00 46.36  ? 56  A   B N9    1 
ATOM 3761 C C8    . A   B 2 56  ? 140.256 121.901 122.123 1.00 49.82  ? 56  A   B C8    1 
ATOM 3762 N N7    . A   B 2 56  ? 139.015 122.188 121.810 1.00 47.71  ? 56  A   B N7    1 
ATOM 3763 C C5    . A   B 2 56  ? 139.121 123.365 121.087 1.00 43.15  ? 56  A   B C5    1 
ATOM 3764 C C6    . A   B 2 56  ? 138.173 124.193 120.468 1.00 45.07  ? 56  A   B C6    1 
ATOM 3765 N N6    . A   B 2 56  ? 136.862 123.953 120.475 1.00 47.80  ? 56  A   B N6    1 
ATOM 3766 N N1    . A   B 2 56  ? 138.621 125.294 119.827 1.00 48.73  ? 56  A   B N1    1 
ATOM 3767 C C2    . A   B 2 56  ? 139.936 125.537 119.810 1.00 49.37  ? 56  A   B C2    1 
ATOM 3768 N N3    . A   B 2 56  ? 140.921 124.838 120.357 1.00 47.28  ? 56  A   B N3    1 
ATOM 3769 C C4    . A   B 2 56  ? 140.439 123.755 120.984 1.00 44.18  ? 56  A   B C4    1 
ATOM 3770 P P     . A   B 2 57  ? 143.648 124.724 126.061 1.00 63.55  ? 57  A   B P     1 
ATOM 3771 O OP1   . A   B 2 57  ? 144.769 125.005 126.990 1.00 63.03  ? 57  A   B OP1   1 
ATOM 3772 O OP2   . A   B 2 57  ? 142.356 124.221 126.586 1.00 54.55  ? 57  A   B OP2   1 
ATOM 3773 O "O5'" . A   B 2 57  ? 143.360 126.050 125.229 1.00 53.59  ? 57  A   B "O5'" 1 
ATOM 3774 C "C5'" . A   B 2 57  ? 144.424 126.843 124.726 1.00 50.13  ? 57  A   B "C5'" 1 
ATOM 3775 C "C4'" . A   B 2 57  ? 143.913 128.127 124.124 1.00 48.21  ? 57  A   B "C4'" 1 
ATOM 3776 O "O4'" . A   B 2 57  ? 143.146 127.832 122.933 1.00 45.50  ? 57  A   B "O4'" 1 
ATOM 3777 C "C3'" . A   B 2 57  ? 142.964 128.933 124.996 1.00 49.41  ? 57  A   B "C3'" 1 
ATOM 3778 O "O3'" . A   B 2 57  ? 143.654 129.762 125.915 1.00 48.97  ? 57  A   B "O3'" 1 
ATOM 3779 C "C2'" . A   B 2 57  ? 142.143 129.716 123.980 1.00 45.97  ? 57  A   B "C2'" 1 
ATOM 3780 O "O2'" . A   B 2 57  ? 142.848 130.871 123.551 1.00 47.84  ? 57  A   B "O2'" 1 
ATOM 3781 C "C1'" . A   B 2 57  ? 142.072 128.737 122.810 1.00 45.99  ? 57  A   B "C1'" 1 
ATOM 3782 N N9    . A   B 2 57  ? 140.815 127.966 122.757 1.00 49.33  ? 57  A   B N9    1 
ATOM 3783 C C8    . A   B 2 57  ? 140.636 126.665 123.146 1.00 50.07  ? 57  A   B C8    1 
ATOM 3784 N N7    . A   B 2 57  ? 139.421 126.215 122.962 1.00 47.04  ? 57  A   B N7    1 
ATOM 3785 C C5    . A   B 2 57  ? 138.755 127.293 122.404 1.00 45.99  ? 57  A   B C5    1 
ATOM 3786 C C6    . A   B 2 57  ? 137.430 127.457 121.972 1.00 46.47  ? 57  A   B C6    1 
ATOM 3787 N N6    . A   B 2 57  ? 136.506 126.502 122.048 1.00 49.51  ? 57  A   B N6    1 
ATOM 3788 N N1    . A   B 2 57  ? 137.075 128.649 121.456 1.00 48.45  ? 57  A   B N1    1 
ATOM 3789 C C2    . A   B 2 57  ? 138.000 129.615 121.379 1.00 49.35  ? 57  A   B C2    1 
ATOM 3790 N N3    . A   B 2 57  ? 139.278 129.577 121.753 1.00 48.27  ? 57  A   B N3    1 
ATOM 3791 C C4    . A   B 2 57  ? 139.599 128.375 122.261 1.00 47.64  ? 57  A   B C4    1 
ATOM 3792 P P     . A   B 2 58  ? 143.002 130.127 127.334 1.00 54.62  ? 58  A   B P     1 
ATOM 3793 O OP1   . A   B 2 58  ? 144.047 130.792 128.146 1.00 50.32  ? 58  A   B OP1   1 
ATOM 3794 O OP2   . A   B 2 58  ? 142.314 128.924 127.855 1.00 58.03  ? 58  A   B OP2   1 
ATOM 3795 O "O5'" . A   B 2 58  ? 141.886 131.206 126.984 1.00 50.89  ? 58  A   B "O5'" 1 
ATOM 3796 C "C5'" . A   B 2 58  ? 142.244 132.524 126.605 1.00 46.40  ? 58  A   B "C5'" 1 
ATOM 3797 C "C4'" . A   B 2 58  ? 141.081 133.262 125.994 1.00 44.40  ? 58  A   B "C4'" 1 
ATOM 3798 O "O4'" . A   B 2 58  ? 140.587 132.537 124.842 1.00 41.27  ? 58  A   B "O4'" 1 
ATOM 3799 C "C3'" . A   B 2 58  ? 139.849 133.431 126.867 1.00 42.97  ? 58  A   B "C3'" 1 
ATOM 3800 O "O3'" . A   B 2 58  ? 139.970 134.485 127.801 1.00 45.04  ? 58  A   B "O3'" 1 
ATOM 3801 C "C2'" . A   B 2 58  ? 138.757 133.670 125.837 1.00 40.57  ? 58  A   B "C2'" 1 
ATOM 3802 O "O2'" . A   B 2 58  ? 138.813 135.002 125.350 1.00 39.73  ? 58  A   B "O2'" 1 
ATOM 3803 C "C1'" . A   B 2 58  ? 139.195 132.732 124.716 1.00 42.90  ? 58  A   B "C1'" 1 
ATOM 3804 N N9    . A   B 2 58  ? 138.515 131.430 124.806 1.00 46.27  ? 58  A   B N9    1 
ATOM 3805 C C8    . A   B 2 58  ? 138.954 130.253 125.355 1.00 47.07  ? 58  A   B C8    1 
ATOM 3806 N N7    . A   B 2 58  ? 138.082 129.277 125.272 1.00 45.30  ? 58  A   B N7    1 
ATOM 3807 C C5    . A   B 2 58  ? 136.998 129.859 124.633 1.00 46.70  ? 58  A   B C5    1 
ATOM 3808 C C6    . A   B 2 58  ? 135.743 129.368 124.242 1.00 51.57  ? 58  A   B C6    1 
ATOM 3809 N N6    . A   B 2 58  ? 135.332 128.114 124.440 1.00 53.25  ? 58  A   B N6    1 
ATOM 3810 N N1    . A   B 2 58  ? 134.906 130.227 123.623 1.00 51.99  ? 58  A   B N1    1 
ATOM 3811 C C2    . A   B 2 58  ? 135.297 131.488 123.412 1.00 46.19  ? 58  A   B C2    1 
ATOM 3812 N N3    . A   B 2 58  ? 136.447 132.065 123.733 1.00 41.59  ? 58  A   B N3    1 
ATOM 3813 C C4    . A   B 2 58  ? 137.254 131.185 124.345 1.00 44.70  ? 58  A   B C4    1 
ATOM 3814 P P     . A   B 2 59  ? 140.068 134.180 129.375 1.00 42.58  ? 59  A   B P     1 
ATOM 3815 O OP1   . A   B 2 59  ? 140.863 132.944 129.578 1.00 43.02  ? 59  A   B OP1   1 
ATOM 3816 O OP2   . A   B 2 59  ? 138.702 134.288 129.940 1.00 45.49  ? 59  A   B OP2   1 
ATOM 3817 O "O5'" . A   B 2 59  ? 140.921 135.396 129.942 1.00 38.13  ? 59  A   B "O5'" 1 
ATOM 3818 C "C5'" . A   B 2 59  ? 142.280 135.566 129.571 1.00 43.42  ? 59  A   B "C5'" 1 
ATOM 3819 C "C4'" . A   B 2 59  ? 142.411 136.458 128.362 1.00 43.95  ? 59  A   B "C4'" 1 
ATOM 3820 O "O4'" . A   B 2 59  ? 141.567 137.624 128.522 1.00 44.42  ? 59  A   B "O4'" 1 
ATOM 3821 C "C3'" . A   B 2 59  ? 143.793 137.027 128.095 1.00 40.99  ? 59  A   B "C3'" 1 
ATOM 3822 O "O3'" . A   B 2 59  ? 144.639 136.113 127.423 1.00 37.41  ? 59  A   B "O3'" 1 
ATOM 3823 C "C2'" . A   B 2 59  ? 143.488 138.284 127.292 1.00 41.31  ? 59  A   B "C2'" 1 
ATOM 3824 O "O2'" . A   B 2 59  ? 143.227 137.956 125.937 1.00 38.23  ? 59  A   B "O2'" 1 
ATOM 3825 C "C1'" . A   B 2 59  ? 142.178 138.746 127.931 1.00 41.96  ? 59  A   B "C1'" 1 
ATOM 3826 N N9    . A   B 2 59  ? 142.371 139.770 128.974 1.00 43.50  ? 59  A   B N9    1 
ATOM 3827 C C8    . A   B 2 59  ? 143.122 139.717 130.121 1.00 45.59  ? 59  A   B C8    1 
ATOM 3828 N N7    . A   B 2 59  ? 143.066 140.800 130.851 1.00 45.76  ? 59  A   B N7    1 
ATOM 3829 C C5    . A   B 2 59  ? 142.205 141.617 130.142 1.00 47.55  ? 59  A   B C5    1 
ATOM 3830 C C6    . A   B 2 59  ? 141.723 142.909 130.381 1.00 50.25  ? 59  A   B C6    1 
ATOM 3831 N N6    . A   B 2 59  ? 142.055 143.637 131.447 1.00 49.35  ? 59  A   B N6    1 
ATOM 3832 N N1    . A   B 2 59  ? 140.875 143.435 129.473 1.00 54.43  ? 59  A   B N1    1 
ATOM 3833 C C2    . A   B 2 59  ? 140.537 142.708 128.401 1.00 50.70  ? 59  A   B C2    1 
ATOM 3834 N N3    . A   B 2 59  ? 140.927 141.484 128.067 1.00 46.59  ? 59  A   B N3    1 
ATOM 3835 C C4    . A   B 2 59  ? 141.764 140.994 128.992 1.00 45.20  ? 59  A   B C4    1 
ATOM 3836 P P     . C   B 2 60  ? 146.040 135.691 128.078 1.00 45.79  ? 60  C   B P     1 
ATOM 3837 O OP1   . C   B 2 60  ? 146.565 134.528 127.324 1.00 48.05  ? 60  C   B OP1   1 
ATOM 3838 O OP2   . C   B 2 60  ? 145.851 135.589 129.545 1.00 44.23  ? 60  C   B OP2   1 
ATOM 3839 O "O5'" . C   B 2 60  ? 146.981 136.939 127.785 1.00 48.15  ? 60  C   B "O5'" 1 
ATOM 3840 C "C5'" . C   B 2 60  ? 147.391 137.236 126.460 1.00 44.14  ? 60  C   B "C5'" 1 
ATOM 3841 C "C4'" . C   B 2 60  ? 147.808 138.676 126.312 1.00 44.39  ? 60  C   B "C4'" 1 
ATOM 3842 O "O4'" . C   B 2 60  ? 146.785 139.549 126.852 1.00 41.69  ? 60  C   B "O4'" 1 
ATOM 3843 C "C3'" . C   B 2 60  ? 149.063 139.093 127.054 1.00 45.02  ? 60  C   B "C3'" 1 
ATOM 3844 O "O3'" . C   B 2 60  ? 150.253 138.699 126.400 1.00 50.17  ? 60  C   B "O3'" 1 
ATOM 3845 C "C2'" . C   B 2 60  ? 148.894 140.602 127.159 1.00 47.10  ? 60  C   B "C2'" 1 
ATOM 3846 O "O2'" . C   B 2 60  ? 149.235 141.228 125.932 1.00 54.22  ? 60  C   B "O2'" 1 
ATOM 3847 C "C1'" . C   B 2 60  ? 147.381 140.725 127.357 1.00 42.59  ? 60  C   B "C1'" 1 
ATOM 3848 N N1    . C   B 2 60  ? 147.015 140.889 128.782 1.00 45.20  ? 60  C   B N1    1 
ATOM 3849 C C2    . C   B 2 60  ? 146.969 142.185 129.295 1.00 48.25  ? 60  C   B C2    1 
ATOM 3850 O O2    . C   B 2 60  ? 147.226 143.135 128.546 1.00 52.08  ? 60  C   B O2    1 
ATOM 3851 N N3    . C   B 2 60  ? 146.643 142.378 130.589 1.00 47.77  ? 60  C   B N3    1 
ATOM 3852 C C4    . C   B 2 60  ? 146.370 141.335 131.367 1.00 44.45  ? 60  C   B C4    1 
ATOM 3853 N N4    . C   B 2 60  ? 146.053 141.575 132.639 1.00 46.02  ? 60  C   B N4    1 
ATOM 3854 C C5    . C   B 2 60  ? 146.412 140.001 130.878 1.00 43.86  ? 60  C   B C5    1 
ATOM 3855 C C6    . C   B 2 60  ? 146.733 139.827 129.594 1.00 46.54  ? 60  C   B C6    1 
ATOM 3856 P P     . G   B 2 61  ? 151.296 137.743 127.155 1.00 60.83  ? 61  G   B P     1 
ATOM 3857 O OP1   . G   B 2 61  ? 152.645 137.997 126.593 1.00 61.36  ? 61  G   B OP1   1 
ATOM 3858 O OP2   . G   B 2 61  ? 150.742 136.367 127.157 1.00 56.20  ? 61  G   B OP2   1 
ATOM 3859 O "O5'" . G   B 2 61  ? 151.292 138.286 128.651 1.00 54.42  ? 61  G   B "O5'" 1 
ATOM 3860 C "C5'" . G   B 2 61  ? 152.404 138.998 129.170 1.00 55.27  ? 61  G   B "C5'" 1 
ATOM 3861 C "C4'" . G   B 2 61  ? 151.969 140.088 130.116 1.00 53.15  ? 61  G   B "C4'" 1 
ATOM 3862 O "O4'" . G   B 2 61  ? 150.526 140.078 130.248 1.00 50.85  ? 61  G   B "O4'" 1 
ATOM 3863 C "C3'" . G   B 2 61  ? 152.471 139.966 131.545 1.00 51.18  ? 61  G   B "C3'" 1 
ATOM 3864 O "O3'" . G   B 2 61  ? 153.793 140.446 131.704 1.00 51.57  ? 61  G   B "O3'" 1 
ATOM 3865 C "C2'" . G   B 2 61  ? 151.436 140.758 132.328 1.00 49.22  ? 61  G   B "C2'" 1 
ATOM 3866 O "O2'" . G   B 2 61  ? 151.665 142.151 132.189 1.00 53.49  ? 61  G   B "O2'" 1 
ATOM 3867 C "C1'" . G   B 2 61  ? 150.159 140.410 131.569 1.00 46.69  ? 61  G   B "C1'" 1 
ATOM 3868 N N9    . G   B 2 61  ? 149.447 139.257 132.150 1.00 46.59  ? 61  G   B N9    1 
ATOM 3869 C C8    . G   B 2 61  ? 149.364 138.001 131.604 1.00 47.03  ? 61  G   B C8    1 
ATOM 3870 N N7    . G   B 2 61  ? 148.659 137.172 132.318 1.00 45.97  ? 61  G   B N7    1 
ATOM 3871 C C5    . G   B 2 61  ? 148.242 137.930 133.400 1.00 48.46  ? 61  G   B C5    1 
ATOM 3872 C C6    . G   B 2 61  ? 147.454 137.565 134.515 1.00 47.43  ? 61  G   B C6    1 
ATOM 3873 O O6    . G   B 2 61  ? 146.940 136.468 134.754 1.00 49.42  ? 61  G   B O6    1 
ATOM 3874 N N1    . G   B 2 61  ? 147.263 138.630 135.387 1.00 43.61  ? 61  G   B N1    1 
ATOM 3875 C C2    . G   B 2 61  ? 147.780 139.886 135.208 1.00 45.85  ? 61  G   B C2    1 
ATOM 3876 N N2    . G   B 2 61  ? 147.493 140.784 136.160 1.00 46.19  ? 61  G   B N2    1 
ATOM 3877 N N3    . G   B 2 61  ? 148.525 140.238 134.176 1.00 51.97  ? 61  G   B N3    1 
ATOM 3878 C C4    . G   B 2 61  ? 148.716 139.218 133.315 1.00 50.14  ? 61  G   B C4    1 
ATOM 3879 P P     . C   B 2 62  ? 154.826 139.664 132.651 1.00 52.67  ? 62  C   B P     1 
ATOM 3880 O OP1   . C   B 2 62  ? 156.173 140.247 132.437 1.00 56.00  ? 62  C   B OP1   1 
ATOM 3881 O OP2   . C   B 2 62  ? 154.618 138.207 132.466 1.00 51.46  ? 62  C   B OP2   1 
ATOM 3882 O "O5'" . C   B 2 62  ? 154.359 140.051 134.121 1.00 52.22  ? 62  C   B "O5'" 1 
ATOM 3883 C "C5'" . C   B 2 62  ? 154.356 141.404 134.551 1.00 51.84  ? 62  C   B "C5'" 1 
ATOM 3884 C "C4'" . C   B 2 62  ? 153.605 141.564 135.848 1.00 51.70  ? 62  C   B "C4'" 1 
ATOM 3885 O "O4'" . C   B 2 62  ? 152.208 141.213 135.654 1.00 53.49  ? 62  C   B "O4'" 1 
ATOM 3886 C "C3'" . C   B 2 62  ? 154.053 140.658 136.981 1.00 50.84  ? 62  C   B "C3'" 1 
ATOM 3887 O "O3'" . C   B 2 62  ? 155.208 141.129 137.650 1.00 54.19  ? 62  C   B "O3'" 1 
ATOM 3888 C "C2'" . C   B 2 62  ? 152.816 140.602 137.861 1.00 50.81  ? 62  C   B "C2'" 1 
ATOM 3889 O "O2'" . C   B 2 62  ? 152.688 141.801 138.609 1.00 52.94  ? 62  C   B "O2'" 1 
ATOM 3890 C "C1'" . C   B 2 62  ? 151.706 140.577 136.812 1.00 49.35  ? 62  C   B "C1'" 1 
ATOM 3891 N N1    . C   B 2 62  ? 151.284 139.197 136.457 1.00 47.13  ? 62  C   B N1    1 
ATOM 3892 C C2    . C   B 2 62  ? 150.502 138.424 137.329 1.00 49.34  ? 62  C   B C2    1 
ATOM 3893 O O2    . C   B 2 62  ? 150.159 138.887 138.425 1.00 53.98  ? 62  C   B O2    1 
ATOM 3894 N N3    . C   B 2 62  ? 150.135 137.177 136.959 1.00 49.46  ? 62  C   B N3    1 
ATOM 3895 C C4    . C   B 2 62  ? 150.505 136.688 135.779 1.00 46.29  ? 62  C   B C4    1 
ATOM 3896 N N4    . C   B 2 62  ? 150.121 135.455 135.454 1.00 48.29  ? 62  C   B N4    1 
ATOM 3897 C C5    . C   B 2 62  ? 151.289 137.440 134.871 1.00 47.46  ? 62  C   B C5    1 
ATOM 3898 C C6    . C   B 2 62  ? 151.642 138.668 135.251 1.00 50.04  ? 62  C   B C6    1 
ATOM 3899 P P     . C   B 2 63  ? 156.277 140.085 138.238 1.00 61.54  ? 63  C   B P     1 
ATOM 3900 O OP1   . C   B 2 63  ? 157.370 140.872 138.861 1.00 66.65  ? 63  C   B OP1   1 
ATOM 3901 O OP2   . C   B 2 63  ? 156.591 139.082 137.192 1.00 54.53  ? 63  C   B OP2   1 
ATOM 3902 O "O5'" . C   B 2 63  ? 155.491 139.350 139.410 1.00 55.60  ? 63  C   B "O5'" 1 
ATOM 3903 C "C5'" . C   B 2 63  ? 155.182 140.038 140.610 1.00 54.73  ? 63  C   B "C5'" 1 
ATOM 3904 C "C4'" . C   B 2 63  ? 154.302 139.218 141.518 1.00 50.86  ? 63  C   B "C4'" 1 
ATOM 3905 O "O4'" . C   B 2 63  ? 153.082 138.834 140.830 1.00 50.02  ? 63  C   B "O4'" 1 
ATOM 3906 C "C3'" . C   B 2 63  ? 154.872 137.896 141.994 1.00 54.55  ? 63  C   B "C3'" 1 
ATOM 3907 O "O3'" . C   B 2 63  ? 155.816 138.029 143.041 1.00 60.06  ? 63  C   B "O3'" 1 
ATOM 3908 C "C2'" . C   B 2 63  ? 153.619 137.139 142.401 1.00 53.30  ? 63  C   B "C2'" 1 
ATOM 3909 O "O2'" . C   B 2 63  ? 153.147 137.600 143.656 1.00 54.68  ? 63  C   B "O2'" 1 
ATOM 3910 C "C1'" . C   B 2 63  ? 152.632 137.588 141.325 1.00 52.11  ? 63  C   B "C1'" 1 
ATOM 3911 N N1    . C   B 2 63  ? 152.535 136.613 140.209 1.00 51.78  ? 63  C   B N1    1 
ATOM 3912 C C2    . C   B 2 63  ? 151.836 135.408 140.392 1.00 53.25  ? 63  C   B C2    1 
ATOM 3913 O O2    . C   B 2 63  ? 151.302 135.170 141.487 1.00 57.59  ? 63  C   B O2    1 
ATOM 3914 N N3    . C   B 2 63  ? 151.752 134.527 139.369 1.00 51.67  ? 63  C   B N3    1 
ATOM 3915 C C4    . C   B 2 63  ? 152.325 134.806 138.200 1.00 51.91  ? 63  C   B C4    1 
ATOM 3916 N N4    . C   B 2 63  ? 152.218 133.914 137.215 1.00 56.43  ? 63  C   B N4    1 
ATOM 3917 C C5    . C   B 2 63  ? 153.038 136.016 137.984 1.00 50.18  ? 63  C   B C5    1 
ATOM 3918 C C6    . C   B 2 63  ? 153.115 136.878 139.001 1.00 51.77  ? 63  C   B C6    1 
ATOM 3919 P P     . U   B 2 64  ? 157.034 136.986 143.159 1.00 64.33  ? 64  U   B P     1 
ATOM 3920 O OP1   . U   B 2 64  ? 157.896 137.418 144.285 1.00 67.26  ? 64  U   B OP1   1 
ATOM 3921 O OP2   . U   B 2 64  ? 157.626 136.814 141.811 1.00 60.13  ? 64  U   B OP2   1 
ATOM 3922 O "O5'" . U   B 2 64  ? 156.338 135.612 143.567 1.00 60.19  ? 64  U   B "O5'" 1 
ATOM 3923 C "C5'" . U   B 2 64  ? 155.699 135.466 144.826 1.00 60.98  ? 64  U   B "C5'" 1 
ATOM 3924 C "C4'" . U   B 2 64  ? 154.847 134.222 144.885 1.00 61.52  ? 64  U   B "C4'" 1 
ATOM 3925 O "O4'" . U   B 2 64  ? 153.946 134.170 143.748 1.00 58.89  ? 64  U   B "O4'" 1 
ATOM 3926 C "C3'" . U   B 2 64  ? 155.590 132.902 144.817 1.00 64.55  ? 64  U   B "C3'" 1 
ATOM 3927 O "O3'" . U   B 2 64  ? 156.178 132.534 146.052 1.00 72.54  ? 64  U   B "O3'" 1 
ATOM 3928 C "C2'" . U   B 2 64  ? 154.507 131.940 144.351 1.00 65.98  ? 64  U   B "C2'" 1 
ATOM 3929 O "O2'" . U   B 2 64  ? 153.661 131.576 145.430 1.00 71.40  ? 64  U   B "O2'" 1 
ATOM 3930 C "C1'" . U   B 2 64  ? 153.708 132.824 143.388 1.00 59.35  ? 64  U   B "C1'" 1 
ATOM 3931 N N1    . U   B 2 64  ? 154.104 132.617 141.974 1.00 57.18  ? 64  U   B N1    1 
ATOM 3932 C C2    . U   B 2 64  ? 153.708 131.451 141.337 1.00 55.73  ? 64  U   B C2    1 
ATOM 3933 O O2    . U   B 2 64  ? 153.048 130.579 141.869 1.00 59.73  ? 64  U   B O2    1 
ATOM 3934 N N3    . U   B 2 64  ? 154.112 131.325 140.034 1.00 55.14  ? 64  U   B N3    1 
ATOM 3935 C C4    . U   B 2 64  ? 154.854 132.229 139.309 1.00 58.75  ? 64  U   B C4    1 
ATOM 3936 O O4    . U   B 2 64  ? 155.139 131.972 138.140 1.00 62.67  ? 64  U   B O4    1 
ATOM 3937 C C5    . U   B 2 64  ? 155.224 133.408 140.026 1.00 58.52  ? 64  U   B C5    1 
ATOM 3938 C C6    . U   B 2 64  ? 154.845 133.557 141.299 1.00 58.29  ? 64  U   B C6    1 
ATOM 3939 P P     . A   B 2 65  ? 157.761 132.279 146.148 1.00 77.18  ? 65  A   B P     1 
ATOM 3940 O OP1   . A   B 2 65  ? 158.259 132.943 147.378 1.00 82.82  ? 65  A   B OP1   1 
ATOM 3941 O OP2   . A   B 2 65  ? 158.353 132.629 144.833 1.00 70.48  ? 65  A   B OP2   1 
ATOM 3942 O "O5'" . A   B 2 65  ? 157.895 130.703 146.337 1.00 82.53  ? 65  A   B "O5'" 1 
ATOM 3943 C "C5'" . A   B 2 65  ? 157.460 129.810 145.318 1.00 83.14  ? 65  A   B "C5'" 1 
ATOM 3944 C "C4'" . A   B 2 65  ? 157.864 128.385 145.596 1.00 88.62  ? 65  A   B "C4'" 1 
ATOM 3945 O "O4'" . A   B 2 65  ? 157.147 127.514 144.680 1.00 87.90  ? 65  A   B "O4'" 1 
ATOM 3946 C "C3'" . A   B 2 65  ? 159.343 128.079 145.395 1.00 95.12  ? 65  A   B "C3'" 1 
ATOM 3947 O "O3'" . A   B 2 65  ? 159.720 127.013 146.265 1.00 102.24 ? 65  A   B "O3'" 1 
ATOM 3948 C "C2'" . A   B 2 65  ? 159.377 127.581 143.957 1.00 92.70  ? 65  A   B "C2'" 1 
ATOM 3949 O "O2'" . A   B 2 65  ? 160.488 126.769 143.643 1.00 95.10  ? 65  A   B "O2'" 1 
ATOM 3950 C "C1'" . A   B 2 65  ? 158.070 126.800 143.881 1.00 88.14  ? 65  A   B "C1'" 1 
ATOM 3951 N N9    . A   B 2 65  ? 157.515 126.692 142.532 1.00 86.89  ? 65  A   B N9    1 
ATOM 3952 C C8    . A   B 2 65  ? 156.837 127.647 141.820 1.00 81.52  ? 65  A   B C8    1 
ATOM 3953 N N7    . A   B 2 65  ? 156.455 127.245 140.634 1.00 80.47  ? 65  A   B N7    1 
ATOM 3954 C C5    . A   B 2 65  ? 156.908 125.935 140.566 1.00 87.66  ? 65  A   B C5    1 
ATOM 3955 C C6    . A   B 2 65  ? 156.825 124.950 139.568 1.00 90.46  ? 65  A   B C6    1 
ATOM 3956 N N6    . A   B 2 65  ? 156.228 125.139 138.389 1.00 88.16  ? 65  A   B N6    1 
ATOM 3957 N N1    . A   B 2 65  ? 157.384 123.746 139.823 1.00 92.07  ? 65  A   B N1    1 
ATOM 3958 C C2    . A   B 2 65  ? 157.988 123.551 141.002 1.00 88.88  ? 65  A   B C2    1 
ATOM 3959 N N3    . A   B 2 65  ? 158.127 124.397 142.018 1.00 86.69  ? 65  A   B N3    1 
ATOM 3960 C C4    . A   B 2 65  ? 157.557 125.580 141.732 1.00 87.61  ? 65  A   B C4    1 
ATOM 3961 P P     . U   B 2 66  ? 160.718 127.280 147.495 1.00 112.44 ? 66  U   B P     1 
ATOM 3962 O OP1   . U   B 2 66  ? 161.538 128.475 147.179 1.00 107.88 ? 66  U   B OP1   1 
ATOM 3963 O OP2   . U   B 2 66  ? 161.384 125.997 147.830 1.00 111.68 ? 66  U   B OP2   1 
ATOM 3964 O "O5'" . U   B 2 66  ? 159.747 127.652 148.699 1.00 105.78 ? 66  U   B "O5'" 1 
ATOM 3965 C "C5'" . U   B 2 66  ? 159.180 126.644 149.529 1.00 104.50 ? 66  U   B "C5'" 1 
ATOM 3966 C "C4'" . U   B 2 66  ? 158.589 127.225 150.791 1.00 107.86 ? 66  U   B "C4'" 1 
ATOM 3967 O "O4'" . U   B 2 66  ? 159.545 128.152 151.376 1.00 113.39 ? 66  U   B "O4'" 1 
ATOM 3968 C "C3'" . U   B 2 66  ? 157.293 128.011 150.607 1.00 107.27 ? 66  U   B "C3'" 1 
ATOM 3969 O "O3'" . U   B 2 66  ? 156.463 127.843 151.757 1.00 109.32 ? 66  U   B "O3'" 1 
ATOM 3970 C "C2'" . U   B 2 66  ? 157.778 129.455 150.538 1.00 107.75 ? 66  U   B "C2'" 1 
ATOM 3971 O "O2'" . U   B 2 66  ? 156.814 130.416 150.913 1.00 105.92 ? 66  U   B "O2'" 1 
ATOM 3972 C "C1'" . U   B 2 66  ? 158.958 129.433 151.504 1.00 114.39 ? 66  U   B "C1'" 1 
ATOM 3973 N N1    . U   B 2 66  ? 159.989 130.434 151.198 1.00 118.46 ? 66  U   B N1    1 
ATOM 3974 C C2    . U   B 2 66  ? 160.065 131.556 151.999 1.00 120.52 ? 66  U   B C2    1 
ATOM 3975 O O2    . U   B 2 66  ? 159.315 131.749 152.940 1.00 118.38 ? 66  U   B O2    1 
ATOM 3976 N N3    . U   B 2 66  ? 161.050 132.447 151.653 1.00 124.52 ? 66  U   B N3    1 
ATOM 3977 C C4    . U   B 2 66  ? 161.949 132.329 150.611 1.00 126.72 ? 66  U   B C4    1 
ATOM 3978 O O4    . U   B 2 66  ? 162.782 133.216 150.425 1.00 130.57 ? 66  U   B O4    1 
ATOM 3979 C C5    . U   B 2 66  ? 161.805 131.139 149.831 1.00 121.52 ? 66  U   B C5    1 
ATOM 3980 C C6    . U   B 2 66  ? 160.853 130.256 150.145 1.00 117.71 ? 66  U   B C6    1 
ATOM 3981 P P     . A   B 2 67  ? 154.882 127.604 151.592 1.00 105.03 ? 67  A   B P     1 
ATOM 3982 O OP1   . A   B 2 67  ? 154.174 128.584 152.452 1.00 105.83 ? 67  A   B OP1   1 
ATOM 3983 O OP2   . A   B 2 67  ? 154.616 126.153 151.753 1.00 95.25  ? 67  A   B OP2   1 
ATOM 3984 O "O5'" . A   B 2 67  ? 154.580 127.989 150.078 1.00 99.35  ? 67  A   B "O5'" 1 
ATOM 3985 C "C5'" . A   B 2 67  ? 153.954 129.219 149.743 1.00 95.58  ? 67  A   B "C5'" 1 
ATOM 3986 C "C4'" . A   B 2 67  ? 153.449 129.199 148.325 1.00 89.36  ? 67  A   B "C4'" 1 
ATOM 3987 O "O4'" . A   B 2 67  ? 154.524 128.809 147.438 1.00 85.81  ? 67  A   B "O4'" 1 
ATOM 3988 C "C3'" . A   B 2 67  ? 152.343 128.197 148.043 1.00 86.80  ? 67  A   B "C3'" 1 
ATOM 3989 O "O3'" . A   B 2 67  ? 151.067 128.717 148.373 1.00 88.25  ? 67  A   B "O3'" 1 
ATOM 3990 C "C2'" . A   B 2 67  ? 152.510 127.902 146.557 1.00 83.61  ? 67  A   B "C2'" 1 
ATOM 3991 O "O2'" . A   B 2 67  ? 151.887 128.911 145.776 1.00 82.13  ? 67  A   B "O2'" 1 
ATOM 3992 C "C1'" . A   B 2 67  ? 154.021 128.029 146.378 1.00 82.06  ? 67  A   B "C1'" 1 
ATOM 3993 N N9    . A   B 2 67  ? 154.736 126.738 146.367 1.00 83.78  ? 67  A   B N9    1 
ATOM 3994 C C8    . A   B 2 67  ? 155.610 126.283 147.319 1.00 88.84  ? 67  A   B C8    1 
ATOM 3995 N N7    . A   B 2 67  ? 156.138 125.117 147.045 1.00 89.61  ? 67  A   B N7    1 
ATOM 3996 C C5    . A   B 2 67  ? 155.582 124.785 145.822 1.00 85.66  ? 67  A   B C5    1 
ATOM 3997 C C6    . A   B 2 67  ? 155.738 123.664 144.990 1.00 85.96  ? 67  A   B C6    1 
ATOM 3998 N N6    . A   B 2 67  ? 156.529 122.629 145.277 1.00 88.44  ? 67  A   B N6    1 
ATOM 3999 N N1    . A   B 2 67  ? 155.041 123.640 143.836 1.00 83.71  ? 67  A   B N1    1 
ATOM 4000 C C2    . A   B 2 67  ? 154.244 124.675 143.542 1.00 82.14  ? 67  A   B C2    1 
ATOM 4001 N N3    . A   B 2 67  ? 154.016 125.783 144.244 1.00 82.85  ? 67  A   B N3    1 
ATOM 4002 C C4    . A   B 2 67  ? 154.721 125.776 145.386 1.00 83.58  ? 67  A   B C4    1 
ATOM 4003 P P     . C   B 2 68  ? 149.936 127.776 149.013 1.00 96.81  ? 68  C   B P     1 
ATOM 4004 O OP1   . C   B 2 68  ? 148.788 128.647 149.367 1.00 85.15  ? 68  C   B OP1   1 
ATOM 4005 O OP2   . C   B 2 68  ? 150.555 126.907 150.045 1.00 101.20 ? 68  C   B OP2   1 
ATOM 4006 O "O5'" . C   B 2 68  ? 149.482 126.859 147.797 1.00 82.93  ? 68  C   B "O5'" 1 
ATOM 4007 C "C5'" . C   B 2 68  ? 148.861 127.432 146.660 1.00 76.98  ? 68  C   B "C5'" 1 
ATOM 4008 C "C4'" . C   B 2 68  ? 148.763 126.441 145.532 1.00 70.99  ? 68  C   B "C4'" 1 
ATOM 4009 O "O4'" . C   B 2 68  ? 150.087 126.080 145.065 1.00 72.74  ? 68  C   B "O4'" 1 
ATOM 4010 C "C3'" . C   B 2 68  ? 148.129 125.108 145.875 1.00 70.32  ? 68  C   B "C3'" 1 
ATOM 4011 O "O3'" . C   B 2 68  ? 146.715 125.163 145.926 1.00 68.42  ? 68  C   B "O3'" 1 
ATOM 4012 C "C2'" . C   B 2 68  ? 148.661 124.202 144.776 1.00 70.62  ? 68  C   B "C2'" 1 
ATOM 4013 O "O2'" . C   B 2 68  ? 147.927 124.388 143.576 1.00 71.99  ? 68  C   B "O2'" 1 
ATOM 4014 C "C1'" . C   B 2 68  ? 150.070 124.759 144.568 1.00 72.94  ? 68  C   B "C1'" 1 
ATOM 4015 N N1    . C   B 2 68  ? 151.106 123.951 145.254 1.00 79.20  ? 68  C   B N1    1 
ATOM 4016 C C2    . C   B 2 68  ? 151.533 122.767 144.640 1.00 83.60  ? 68  C   B C2    1 
ATOM 4017 O O2    . C   B 2 68  ? 151.022 122.451 143.555 1.00 84.42  ? 68  C   B O2    1 
ATOM 4018 N N3    . C   B 2 68  ? 152.478 122.006 145.235 1.00 86.80  ? 68  C   B N3    1 
ATOM 4019 C C4    . C   B 2 68  ? 152.995 122.391 146.400 1.00 85.27  ? 68  C   B C4    1 
ATOM 4020 N N4    . C   B 2 68  ? 153.927 121.613 146.954 1.00 87.18  ? 68  C   B N4    1 
ATOM 4021 C C5    . C   B 2 68  ? 152.585 123.591 147.048 1.00 81.39  ? 68  C   B C5    1 
ATOM 4022 C C6    . C   B 2 68  ? 151.648 124.334 146.446 1.00 81.20  ? 68  C   B C6    1 
ATOM 4023 P P     . A   B 2 69  ? 145.903 124.127 146.846 1.00 73.37  ? 69  A   B P     1 
ATOM 4024 O OP1   . A   B 2 69  ? 144.495 124.587 146.912 1.00 71.06  ? 69  A   B OP1   1 
ATOM 4025 O OP2   . A   B 2 69  ? 146.671 123.925 148.098 1.00 82.12  ? 69  A   B OP2   1 
ATOM 4026 O "O5'" . A   B 2 69  ? 145.943 122.765 146.023 1.00 76.38  ? 69  A   B "O5'" 1 
ATOM 4027 C "C5'" . A   B 2 69  ? 145.333 122.674 144.746 1.00 77.44  ? 69  A   B "C5'" 1 
ATOM 4028 C "C4'" . A   B 2 69  ? 145.770 121.438 144.001 1.00 75.28  ? 69  A   B "C4'" 1 
ATOM 4029 O "O4'" . A   B 2 69  ? 147.197 121.478 143.748 1.00 74.07  ? 69  A   B "O4'" 1 
ATOM 4030 C "C3'" . A   B 2 69  ? 145.569 120.118 144.717 1.00 76.83  ? 69  A   B "C3'" 1 
ATOM 4031 O "O3'" . A   B 2 69  ? 144.231 119.662 144.665 1.00 75.11  ? 69  A   B "O3'" 1 
ATOM 4032 C "C2'" . A   B 2 69  ? 146.556 119.205 144.002 1.00 78.06  ? 69  A   B "C2'" 1 
ATOM 4033 O "O2'" . A   B 2 69  ? 146.033 118.783 142.753 1.00 78.32  ? 69  A   B "O2'" 1 
ATOM 4034 C "C1'" . A   B 2 69  ? 147.716 120.165 143.739 1.00 77.24  ? 69  A   B "C1'" 1 
ATOM 4035 N N9    . A   B 2 69  ? 148.766 120.049 144.767 1.00 82.01  ? 69  A   B N9    1 
ATOM 4036 C C8    . A   B 2 69  ? 148.992 120.843 145.862 1.00 81.90  ? 69  A   B C8    1 
ATOM 4037 N N7    . A   B 2 69  ? 150.015 120.460 146.589 1.00 85.05  ? 69  A   B N7    1 
ATOM 4038 C C5    . A   B 2 69  ? 150.490 119.336 145.930 1.00 89.26  ? 69  A   B C5    1 
ATOM 4039 C C6    . A   B 2 69  ? 151.559 118.458 146.186 1.00 91.39  ? 69  A   B C6    1 
ATOM 4040 N N6    . A   B 2 69  ? 152.386 118.575 147.225 1.00 89.14  ? 69  A   B N6    1 
ATOM 4041 N N1    . A   B 2 69  ? 151.755 117.437 145.324 1.00 94.35  ? 69  A   B N1    1 
ATOM 4042 C C2    . A   B 2 69  ? 150.932 117.307 144.277 1.00 94.78  ? 69  A   B C2    1 
ATOM 4043 N N3    . A   B 2 69  ? 149.896 118.068 143.933 1.00 89.91  ? 69  A   B N3    1 
ATOM 4044 C C4    . A   B 2 69  ? 149.728 119.073 144.808 1.00 88.49  ? 69  A   B C4    1 
ATOM 4045 P P     . G   B 2 70  ? 143.649 118.757 145.855 1.00 78.86  ? 70  G   B P     1 
ATOM 4046 O OP1   . G   B 2 70  ? 142.168 118.789 145.768 1.00 78.74  ? 70  G   B OP1   1 
ATOM 4047 O OP2   . G   B 2 70  ? 144.322 119.156 147.115 1.00 82.48  ? 70  G   B OP2   1 
ATOM 4048 O "O5'" . G   B 2 70  ? 144.139 117.290 145.483 1.00 73.18  ? 70  G   B "O5'" 1 
ATOM 4049 C "C5'" . G   B 2 70  ? 143.837 116.732 144.216 1.00 71.20  ? 70  G   B "C5'" 1 
ATOM 4050 C "C4'" . G   B 2 70  ? 144.638 115.485 143.955 1.00 76.78  ? 70  G   B "C4'" 1 
ATOM 4051 O "O4'" . G   B 2 70  ? 146.041 115.811 143.798 1.00 79.17  ? 70  G   B "O4'" 1 
ATOM 4052 C "C3'" . G   B 2 70  ? 144.630 114.446 145.058 1.00 82.62  ? 70  G   B "C3'" 1 
ATOM 4053 O "O3'" . G   B 2 70  ? 143.449 113.666 145.065 1.00 84.05  ? 70  G   B "O3'" 1 
ATOM 4054 C "C2'" . G   B 2 70  ? 145.889 113.643 144.764 1.00 85.38  ? 70  G   B "C2'" 1 
ATOM 4055 O "O2'" . G   B 2 70  ? 145.655 112.711 143.720 1.00 81.87  ? 70  G   B "O2'" 1 
ATOM 4056 C "C1'" . G   B 2 70  ? 146.832 114.728 144.241 1.00 85.91  ? 70  G   B "C1'" 1 
ATOM 4057 N N9    . G   B 2 70  ? 147.795 115.204 145.258 1.00 91.63  ? 70  G   B N9    1 
ATOM 4058 C C8    . G   B 2 70  ? 147.843 116.442 145.850 1.00 89.94  ? 70  G   B C8    1 
ATOM 4059 N N7    . G   B 2 70  ? 148.826 116.572 146.699 1.00 92.29  ? 70  G   B N7    1 
ATOM 4060 C C5    . G   B 2 70  ? 149.479 115.348 146.664 1.00 97.52  ? 70  G   B C5    1 
ATOM 4061 C C6    . G   B 2 70  ? 150.623 114.886 147.374 1.00 101.52 ? 70  G   B C6    1 
ATOM 4062 O O6    . G   B 2 70  ? 151.326 115.478 148.202 1.00 100.91 ? 70  G   B O6    1 
ATOM 4063 N N1    . G   B 2 70  ? 150.943 113.579 147.032 1.00 105.23 ? 70  G   B N1    1 
ATOM 4064 C C2    . G   B 2 70  ? 150.252 112.811 146.133 1.00 106.51 ? 70  G   B C2    1 
ATOM 4065 N N2    . G   B 2 70  ? 150.721 111.570 145.940 1.00 111.28 ? 70  G   B N2    1 
ATOM 4066 N N3    . G   B 2 70  ? 149.190 113.228 145.465 1.00 103.62 ? 70  G   B N3    1 
ATOM 4067 C C4    . G   B 2 70  ? 148.858 114.497 145.775 1.00 97.71  ? 70  G   B C4    1 
ATOM 4068 P P     . U   B 2 71  ? 142.840 113.140 146.453 1.00 84.78  ? 71  U   B P     1 
ATOM 4069 O OP1   . U   B 2 71  ? 141.450 112.690 146.201 1.00 86.93  ? 71  U   B OP1   1 
ATOM 4070 O OP2   . U   B 2 71  ? 143.099 114.170 147.489 1.00 80.26  ? 71  U   B OP2   1 
ATOM 4071 O "O5'" . U   B 2 71  ? 143.724 111.861 146.793 1.00 87.78  ? 71  U   B "O5'" 1 
ATOM 4072 C "C5'" . U   B 2 71  ? 143.839 110.794 145.867 1.00 88.93  ? 71  U   B "C5'" 1 
ATOM 4073 C "C4'" . U   B 2 71  ? 144.965 109.862 146.232 1.00 91.17  ? 71  U   B "C4'" 1 
ATOM 4074 O "O4'" . U   B 2 71  ? 146.238 110.545 146.100 1.00 93.96  ? 71  U   B "O4'" 1 
ATOM 4075 C "C3'" . U   B 2 71  ? 144.968 109.359 147.664 1.00 97.41  ? 71  U   B "C3'" 1 
ATOM 4076 O "O3'" . U   B 2 71  ? 144.065 108.290 147.873 1.00 98.99  ? 71  U   B "O3'" 1 
ATOM 4077 C "C2'" . U   B 2 71  ? 146.427 108.982 147.880 1.00 101.50 ? 71  U   B "C2'" 1 
ATOM 4078 O "O2'" . U   B 2 71  ? 146.711 107.723 147.287 1.00 101.85 ? 71  U   B "O2'" 1 
ATOM 4079 C "C1'" . U   B 2 71  ? 147.144 110.068 147.074 1.00 98.61  ? 71  U   B "C1'" 1 
ATOM 4080 N N1    . U   B 2 71  ? 147.589 111.210 147.909 1.00 99.75  ? 71  U   B N1    1 
ATOM 4081 C C2    . U   B 2 71  ? 148.729 111.084 148.682 1.00 105.27 ? 71  U   B C2    1 
ATOM 4082 O O2    . U   B 2 71  ? 149.393 110.065 148.733 1.00 108.14 ? 71  U   B O2    1 
ATOM 4083 N N3    . U   B 2 71  ? 149.064 112.200 149.413 1.00 109.01 ? 71  U   B N3    1 
ATOM 4084 C C4    . U   B 2 71  ? 148.395 113.408 149.442 1.00 106.73 ? 71  U   B C4    1 
ATOM 4085 O O4    . U   B 2 71  ? 148.804 114.336 150.141 1.00 110.54 ? 71  U   B O4    1 
ATOM 4086 C C5    . U   B 2 71  ? 147.237 113.462 148.613 1.00 98.93  ? 71  U   B C5    1 
ATOM 4087 C C6    . U   B 2 71  ? 146.892 112.391 147.900 1.00 98.27  ? 71  U   B C6    1 
ATOM 4088 P P     . G   B 2 72  ? 143.210 108.219 149.229 1.00 106.26 ? 72  G   B P     1 
ATOM 4089 O OP1   . G   B 2 72  ? 142.101 107.253 149.026 1.00 102.94 ? 72  G   B OP1   1 
ATOM 4090 O OP2   . G   B 2 72  ? 142.903 109.609 149.648 1.00 102.66 ? 72  G   B OP2   1 
ATOM 4091 O "O5'" . G   B 2 72  ? 144.226 107.593 150.282 1.00 112.43 ? 72  G   B "O5'" 1 
ATOM 4092 C "C5'" . G   B 2 72  ? 144.856 106.348 150.025 1.00 112.37 ? 72  G   B "C5'" 1 
ATOM 4093 C "C4'" . G   B 2 72  ? 146.038 106.123 150.932 1.00 112.78 ? 72  G   B "C4'" 1 
ATOM 4094 O "O4'" . G   B 2 72  ? 147.114 107.030 150.585 1.00 113.23 ? 72  G   B "O4'" 1 
ATOM 4095 C "C3'" . G   B 2 72  ? 145.805 106.380 152.409 1.00 120.10 ? 72  G   B "C3'" 1 
ATOM 4096 O "O3'" . G   B 2 72  ? 145.148 105.306 153.056 1.00 127.01 ? 72  G   B "O3'" 1 
ATOM 4097 C "C2'" . G   B 2 72  ? 147.215 106.632 152.927 1.00 122.59 ? 72  G   B "C2'" 1 
ATOM 4098 O "O2'" . G   B 2 72  ? 147.905 105.407 153.120 1.00 126.90 ? 72  G   B "O2'" 1 
ATOM 4099 C "C1'" . G   B 2 72  ? 147.850 107.363 151.744 1.00 118.81 ? 72  G   B "C1'" 1 
ATOM 4100 N N9    . G   B 2 72  ? 147.849 108.829 151.912 1.00 118.81 ? 72  G   B N9    1 
ATOM 4101 C C8    . G   B 2 72  ? 147.081 109.738 151.230 1.00 114.31 ? 72  G   B C8    1 
ATOM 4102 N N7    . G   B 2 72  ? 147.306 110.974 151.580 1.00 113.29 ? 72  G   B N7    1 
ATOM 4103 C C5    . G   B 2 72  ? 148.288 110.876 152.552 1.00 118.26 ? 72  G   B C5    1 
ATOM 4104 C C6    . G   B 2 72  ? 148.925 111.890 153.309 1.00 122.36 ? 72  G   B C6    1 
ATOM 4105 O O6    . G   B 2 72  ? 148.747 113.110 153.240 1.00 122.22 ? 72  G   B O6    1 
ATOM 4106 N N1    . G   B 2 72  ? 149.867 111.365 154.189 1.00 124.95 ? 72  G   B N1    1 
ATOM 4107 C C2    . G   B 2 72  ? 150.144 110.029 154.331 1.00 124.03 ? 72  G   B C2    1 
ATOM 4108 N N2    . G   B 2 72  ? 151.077 109.703 155.237 1.00 126.61 ? 72  G   B N2    1 
ATOM 4109 N N3    . G   B 2 72  ? 149.549 109.073 153.636 1.00 121.80 ? 72  G   B N3    1 
ATOM 4110 C C4    . G   B 2 72  ? 148.638 109.563 152.768 1.00 120.17 ? 72  G   B C4    1 
ATOM 4111 P P     . A   B 2 73  ? 144.182 105.586 154.307 1.00 138.53 ? 73  A   B P     1 
ATOM 4112 O OP1   . A   B 2 73  ? 143.441 104.334 154.606 1.00 137.68 ? 73  A   B OP1   1 
ATOM 4113 O OP2   . A   B 2 73  ? 143.430 106.837 154.034 1.00 129.78 ? 73  A   B OP2   1 
ATOM 4114 O "O5'" . A   B 2 73  ? 145.186 105.853 155.513 1.00 136.33 ? 73  A   B "O5'" 1 
ATOM 4115 C "C5'" . A   B 2 73  ? 146.086 104.843 155.942 1.00 135.44 ? 73  A   B "C5'" 1 
ATOM 4116 C "C4'" . A   B 2 73  ? 147.113 105.387 156.901 1.00 137.33 ? 73  A   B "C4'" 1 
ATOM 4117 O "O4'" . A   B 2 73  ? 147.974 106.340 156.226 1.00 134.93 ? 73  A   B "O4'" 1 
ATOM 4118 C "C3'" . A   B 2 73  ? 146.568 106.165 158.085 1.00 142.18 ? 73  A   B "C3'" 1 
ATOM 4119 O "O3'" . A   B 2 73  ? 146.088 105.328 159.121 1.00 149.03 ? 73  A   B "O3'" 1 
ATOM 4120 C "C2'" . A   B 2 73  ? 147.758 107.024 158.489 1.00 140.74 ? 73  A   B "C2'" 1 
ATOM 4121 O "O2'" . A   B 2 73  ? 148.706 106.258 159.217 1.00 140.92 ? 73  A   B "O2'" 1 
ATOM 4122 C "C1'" . A   B 2 73  ? 148.359 107.361 157.125 1.00 137.68 ? 73  A   B "C1'" 1 
ATOM 4123 N N9    . A   B 2 73  ? 147.872 108.654 156.609 1.00 133.68 ? 73  A   B N9    1 
ATOM 4124 C C8    . A   B 2 73  ? 146.997 108.861 155.575 1.00 128.87 ? 73  A   B C8    1 
ATOM 4125 N N7    . A   B 2 73  ? 146.747 110.121 155.329 1.00 126.45 ? 73  A   B N7    1 
ATOM 4126 C C5    . A   B 2 73  ? 147.505 110.793 156.273 1.00 127.71 ? 73  A   B C5    1 
ATOM 4127 C C6    . A   B 2 73  ? 147.675 112.160 156.543 1.00 129.90 ? 73  A   B C6    1 
ATOM 4128 N N6    . A   B 2 73  ? 147.061 113.120 155.852 1.00 129.59 ? 73  A   B N6    1 
ATOM 4129 N N1    . A   B 2 73  ? 148.503 112.509 157.553 1.00 132.09 ? 73  A   B N1    1 
ATOM 4130 C C2    . A   B 2 73  ? 149.119 111.539 158.241 1.00 133.98 ? 73  A   B C2    1 
ATOM 4131 N N3    . A   B 2 73  ? 149.036 110.218 158.080 1.00 133.47 ? 73  A   B N3    1 
ATOM 4132 C C4    . A   B 2 73  ? 148.207 109.907 157.068 1.00 131.60 ? 73  A   B C4    1 
ATOM 4133 P P     . A   B 2 74  ? 144.806 105.771 159.981 1.00 154.41 ? 74  A   B P     1 
ATOM 4134 O OP1   . A   B 2 74  ? 144.317 104.583 160.726 1.00 150.56 ? 74  A   B OP1   1 
ATOM 4135 O OP2   . A   B 2 74  ? 143.883 106.514 159.087 1.00 144.46 ? 74  A   B OP2   1 
ATOM 4136 O "O5'" . A   B 2 74  ? 145.398 106.800 161.040 1.00 148.41 ? 74  A   B "O5'" 1 
ATOM 4137 C "C5'" . A   B 2 74  ? 146.462 106.421 161.899 1.00 146.18 ? 74  A   B "C5'" 1 
ATOM 4138 C "C4'" . A   B 2 74  ? 147.109 107.624 162.534 1.00 148.71 ? 74  A   B "C4'" 1 
ATOM 4139 O "O4'" . A   B 2 74  ? 147.760 108.431 161.518 1.00 148.75 ? 74  A   B "O4'" 1 
ATOM 4140 C "C3'" . A   B 2 74  ? 146.164 108.593 163.218 1.00 148.77 ? 74  A   B "C3'" 1 
ATOM 4141 O "O3'" . A   B 2 74  ? 145.773 108.166 164.510 1.00 149.65 ? 74  A   B "O3'" 1 
ATOM 4142 C "C2'" . A   B 2 74  ? 146.959 109.890 163.210 1.00 149.52 ? 74  A   B "C2'" 1 
ATOM 4143 O "O2'" . A   B 2 74  ? 147.947 109.882 164.230 1.00 151.59 ? 74  A   B "O2'" 1 
ATOM 4144 C "C1'" . A   B 2 74  ? 147.663 109.799 161.857 1.00 147.63 ? 74  A   B "C1'" 1 
ATOM 4145 N N9    . A   B 2 74  ? 146.916 110.497 160.793 1.00 143.54 ? 74  A   B N9    1 
ATOM 4146 C C8    . A   B 2 74  ? 146.246 109.939 159.734 1.00 139.97 ? 74  A   B C8    1 
ATOM 4147 N N7    . A   B 2 74  ? 145.680 110.813 158.941 1.00 137.36 ? 74  A   B N7    1 
ATOM 4148 C C5    . A   B 2 74  ? 145.995 112.031 159.520 1.00 139.68 ? 74  A   B C5    1 
ATOM 4149 C C6    . A   B 2 74  ? 145.691 113.353 159.162 1.00 140.37 ? 74  A   B C6    1 
ATOM 4150 N N6    . A   B 2 74  ? 144.967 113.668 158.090 1.00 137.96 ? 74  A   B N6    1 
ATOM 4151 N N1    . A   B 2 74  ? 146.157 114.348 159.949 1.00 142.16 ? 74  A   B N1    1 
ATOM 4152 C C2    . A   B 2 74  ? 146.887 114.027 161.025 1.00 142.52 ? 74  A   B C2    1 
ATOM 4153 N N3    . A   B 2 74  ? 147.237 112.820 161.465 1.00 142.90 ? 74  A   B N3    1 
ATOM 4154 C C4    . A   B 2 74  ? 146.757 111.856 160.660 1.00 142.35 ? 74  A   B C4    1 
ATOM 4155 P P     . G   B 2 75  ? 144.246 108.328 164.977 1.00 146.92 ? 75  G   B P     1 
ATOM 4156 O OP1   . G   B 2 75  ? 143.995 107.378 166.090 1.00 146.11 ? 75  G   B OP1   1 
ATOM 4157 O OP2   . G   B 2 75  ? 143.389 108.292 163.766 1.00 148.57 ? 75  G   B OP2   1 
ATOM 4158 O "O5'" . G   B 2 75  ? 144.187 109.805 165.566 1.00 148.79 ? 75  G   B "O5'" 1 
ATOM 4159 C "C5'" . G   B 2 75  ? 145.148 110.243 166.511 1.00 152.02 ? 75  G   B "C5'" 1 
ATOM 4160 C "C4'" . G   B 2 75  ? 145.277 111.743 166.506 1.00 152.77 ? 75  G   B "C4'" 1 
ATOM 4161 O "O4'" . G   B 2 75  ? 145.826 112.186 165.238 1.00 153.83 ? 75  G   B "O4'" 1 
ATOM 4162 C "C3'" . G   B 2 75  ? 143.979 112.521 166.632 1.00 152.22 ? 75  G   B "C3'" 1 
ATOM 4163 O "O3'" . G   B 2 75  ? 143.513 112.609 167.965 1.00 155.86 ? 75  G   B "O3'" 1 
ATOM 4164 C "C2'" . G   B 2 75  ? 144.342 113.867 166.023 1.00 153.18 ? 75  G   B "C2'" 1 
ATOM 4165 O "O2'" . G   B 2 75  ? 145.079 114.652 166.948 1.00 155.20 ? 75  G   B "O2'" 1 
ATOM 4166 C "C1'" . G   B 2 75  ? 145.283 113.443 164.895 1.00 152.00 ? 75  G   B "C1'" 1 
ATOM 4167 N N9    . G   B 2 75  ? 144.585 113.333 163.599 1.00 147.67 ? 75  G   B N9    1 
ATOM 4168 C C8    . G   B 2 75  ? 144.289 112.204 162.874 1.00 144.96 ? 75  G   B C8    1 
ATOM 4169 N N7    . G   B 2 75  ? 143.662 112.464 161.757 1.00 143.54 ? 75  G   B N7    1 
ATOM 4170 C C5    . G   B 2 75  ? 143.536 113.846 161.744 1.00 144.14 ? 75  G   B C5    1 
ATOM 4171 C C6    . G   B 2 75  ? 142.942 114.720 160.795 1.00 142.92 ? 75  G   B C6    1 
ATOM 4172 O O6    . G   B 2 75  ? 142.393 114.430 159.727 1.00 141.75 ? 75  G   B O6    1 
ATOM 4173 N N1    . G   B 2 75  ? 143.043 116.054 161.182 1.00 143.15 ? 75  G   B N1    1 
ATOM 4174 C C2    . G   B 2 75  ? 143.635 116.484 162.342 1.00 143.57 ? 75  G   B C2    1 
ATOM 4175 N N2    . G   B 2 75  ? 143.644 117.802 162.571 1.00 142.49 ? 75  G   B N2    1 
ATOM 4176 N N3    . G   B 2 75  ? 144.186 115.684 163.232 1.00 145.78 ? 75  G   B N3    1 
ATOM 4177 C C4    . G   B 2 75  ? 144.101 114.391 162.873 1.00 145.91 ? 75  G   B C4    1 
ATOM 4178 P P     . G   B 2 76  ? 141.935 112.632 168.264 1.00 156.24 ? 76  G   B P     1 
ATOM 4179 O OP1   . G   B 2 76  ? 141.740 112.391 169.716 1.00 156.32 ? 76  G   B OP1   1 
ATOM 4180 O OP2   . G   B 2 76  ? 141.274 111.744 167.275 1.00 149.58 ? 76  G   B OP2   1 
ATOM 4181 O "O5'" . G   B 2 76  ? 141.501 114.132 167.945 1.00 153.41 ? 76  G   B "O5'" 1 
ATOM 4182 C "C5'" . G   B 2 76  ? 142.027 115.220 168.691 1.00 152.85 ? 76  G   B "C5'" 1 
ATOM 4183 C "C4'" . G   B 2 76  ? 141.834 116.529 167.967 1.00 152.32 ? 76  G   B "C4'" 1 
ATOM 4184 O "O4'" . G   B 2 76  ? 142.365 116.424 166.625 1.00 151.64 ? 76  G   B "O4'" 1 
ATOM 4185 C "C3'" . G   B 2 76  ? 140.394 116.975 167.768 1.00 151.75 ? 76  G   B "C3'" 1 
ATOM 4186 O "O3'" . G   B 2 76  ? 139.881 117.645 168.906 1.00 157.78 ? 76  G   B "O3'" 1 
ATOM 4187 C "C2'" . G   B 2 76  ? 140.478 117.871 166.537 1.00 148.63 ? 76  G   B "C2'" 1 
ATOM 4188 O "O2'" . G   B 2 76  ? 140.890 119.180 166.897 1.00 150.65 ? 76  G   B "O2'" 1 
ATOM 4189 C "C1'" . G   B 2 76  ? 141.604 117.215 165.740 1.00 148.19 ? 76  G   B "C1'" 1 
ATOM 4190 N N9    . G   B 2 76  ? 141.135 116.373 164.621 1.00 145.85 ? 76  G   B N9    1 
ATOM 4191 C C8    . G   B 2 76  ? 141.271 115.011 164.508 1.00 146.59 ? 76  G   B C8    1 
ATOM 4192 N N7    . G   B 2 76  ? 140.794 114.537 163.390 1.00 144.38 ? 76  G   B N7    1 
ATOM 4193 C C5    . G   B 2 76  ? 140.321 115.654 162.716 1.00 142.77 ? 76  G   B C5    1 
ATOM 4194 C C6    . G   B 2 76  ? 139.692 115.764 161.448 1.00 142.71 ? 76  G   B C6    1 
ATOM 4195 O O6    . G   B 2 76  ? 139.428 114.860 160.648 1.00 142.03 ? 76  G   B O6    1 
ATOM 4196 N N1    . G   B 2 76  ? 139.372 117.082 161.137 1.00 143.25 ? 76  G   B N1    1 
ATOM 4197 C C2    . G   B 2 76  ? 139.628 118.154 161.954 1.00 143.97 ? 76  G   B C2    1 
ATOM 4198 N N2    . G   B 2 76  ? 139.250 119.354 161.494 1.00 142.67 ? 76  G   B N2    1 
ATOM 4199 N N3    . G   B 2 76  ? 140.213 118.068 163.139 1.00 144.44 ? 76  G   B N3    1 
ATOM 4200 C C4    . G   B 2 76  ? 140.532 116.797 163.458 1.00 143.83 ? 76  G   B C4    1 
ATOM 4201 P P     . G   B 2 77  ? 138.342 117.480 169.331 1.00 160.99 ? 77  G   B P     1 
ATOM 4202 O OP1   . G   B 2 77  ? 138.118 118.305 170.546 1.00 162.14 ? 77  G   B OP1   1 
ATOM 4203 O OP2   . G   B 2 77  ? 138.022 116.030 169.351 1.00 157.75 ? 77  G   B OP2   1 
ATOM 4204 O "O5'" . G   B 2 77  ? 137.533 118.151 168.135 1.00 147.91 ? 77  G   B "O5'" 1 
ATOM 4205 C "C5'" . G   B 2 77  ? 137.555 119.556 167.925 1.00 142.97 ? 77  G   B "C5'" 1 
ATOM 4206 C "C4'" . G   B 2 77  ? 136.897 119.909 166.618 1.00 144.07 ? 77  G   B "C4'" 1 
ATOM 4207 O "O4'" . G   B 2 77  ? 137.658 119.334 165.523 1.00 149.64 ? 77  G   B "O4'" 1 
ATOM 4208 C "C3'" . G   B 2 77  ? 135.493 119.354 166.431 1.00 143.65 ? 77  G   B "C3'" 1 
ATOM 4209 O "O3'" . G   B 2 77  ? 134.501 120.159 167.043 1.00 137.51 ? 77  G   B "O3'" 1 
ATOM 4210 C "C2'" . G   B 2 77  ? 135.365 119.256 164.916 1.00 143.87 ? 77  G   B "C2'" 1 
ATOM 4211 O "O2'" . G   B 2 77  ? 135.084 120.529 164.355 1.00 141.30 ? 77  G   B "O2'" 1 
ATOM 4212 C "C1'" . G   B 2 77  ? 136.786 118.858 164.520 1.00 147.75 ? 77  G   B "C1'" 1 
ATOM 4213 N N9    . G   B 2 77  ? 136.955 117.395 164.424 1.00 147.57 ? 77  G   B N9    1 
ATOM 4214 C C8    . G   B 2 77  ? 137.434 116.568 165.411 1.00 149.07 ? 77  G   B C8    1 
ATOM 4215 N N7    . G   B 2 77  ? 137.487 115.314 165.062 1.00 148.97 ? 77  G   B N7    1 
ATOM 4216 C C5    . G   B 2 77  ? 137.015 115.308 163.759 1.00 147.04 ? 77  G   B C5    1 
ATOM 4217 C C6    . G   B 2 77  ? 136.839 114.224 162.863 1.00 145.97 ? 77  G   B C6    1 
ATOM 4218 O O6    . G   B 2 77  ? 137.081 113.025 163.044 1.00 146.72 ? 77  G   B O6    1 
ATOM 4219 N N1    . G   B 2 77  ? 136.336 114.652 161.642 1.00 144.22 ? 77  G   B N1    1 
ATOM 4220 C C2    . G   B 2 77  ? 136.036 115.951 161.328 1.00 143.34 ? 77  G   B C2    1 
ATOM 4221 N N2    . G   B 2 77  ? 135.557 116.147 160.094 1.00 145.18 ? 77  G   B N2    1 
ATOM 4222 N N3    . G   B 2 77  ? 136.190 116.975 162.153 1.00 142.16 ? 77  G   B N3    1 
ATOM 4223 C C4    . G   B 2 77  ? 136.681 116.583 163.347 1.00 144.72 ? 77  G   B C4    1 
ATOM 4224 P P     . A   B 2 78  ? 133.683 119.608 168.311 1.00 138.84 ? 78  A   B P     1 
ATOM 4225 O OP1   . A   B 2 78  ? 134.616 118.839 169.171 1.00 145.40 ? 78  A   B OP1   1 
ATOM 4226 O OP2   . A   B 2 78  ? 132.447 118.958 167.809 1.00 135.99 ? 78  A   B OP2   1 
ATOM 4227 O "O5'" . A   B 2 78  ? 133.262 120.925 169.104 1.00 134.16 ? 78  A   B "O5'" 1 
ATOM 4228 C "C5'" . A   B 2 78  ? 134.214 121.658 169.868 1.00 131.47 ? 78  A   B "C5'" 1 
ATOM 4229 C "C4'" . A   B 2 78  ? 133.764 123.077 170.127 1.00 129.86 ? 78  A   B "C4'" 1 
ATOM 4230 O "O4'" . A   B 2 78  ? 133.300 123.663 168.881 1.00 123.30 ? 78  A   B "O4'" 1 
ATOM 4231 C "C3'" . A   B 2 78  ? 132.618 123.238 171.124 1.00 131.07 ? 78  A   B "C3'" 1 
ATOM 4232 O "O3'" . A   B 2 78  ? 132.784 124.464 171.835 1.00 137.48 ? 78  A   B "O3'" 1 
ATOM 4233 C "C2'" . A   B 2 78  ? 131.395 123.338 170.218 1.00 123.54 ? 78  A   B "C2'" 1 
ATOM 4234 O "O2'" . A   B 2 78  ? 130.294 124.011 170.790 1.00 120.82 ? 78  A   B "O2'" 1 
ATOM 4235 C "C1'" . A   B 2 78  ? 131.961 124.098 169.023 1.00 117.83 ? 78  A   B "C1'" 1 
ATOM 4236 N N9    . A   B 2 78  ? 131.268 123.832 167.762 1.00 113.08 ? 78  A   B N9    1 
ATOM 4237 C C8    . A   B 2 78  ? 131.426 122.749 166.934 1.00 114.25 ? 78  A   B C8    1 
ATOM 4238 N N7    . A   B 2 78  ? 130.676 122.793 165.860 1.00 111.69 ? 78  A   B N7    1 
ATOM 4239 C C5    . A   B 2 78  ? 129.985 123.989 165.986 1.00 108.40 ? 78  A   B C5    1 
ATOM 4240 C C6    . A   B 2 78  ? 129.029 124.625 165.176 1.00 100.82 ? 78  A   B C6    1 
ATOM 4241 N N6    . A   B 2 78  ? 128.583 124.121 164.024 1.00 94.80  ? 78  A   B N6    1 
ATOM 4242 N N1    . A   B 2 78  ? 128.538 125.813 165.592 1.00 98.29  ? 78  A   B N1    1 
ATOM 4243 C C2    . A   B 2 78  ? 128.982 126.323 166.747 1.00 102.26 ? 78  A   B C2    1 
ATOM 4244 N N3    . A   B 2 78  ? 129.877 125.822 167.595 1.00 107.10 ? 78  A   B N3    1 
ATOM 4245 C C4    . A   B 2 78  ? 130.346 124.644 167.150 1.00 110.06 ? 78  A   B C4    1 
ATOM 4246 P P     . U   B 2 79  ? 132.798 124.473 173.442 1.00 148.27 ? 79  U   B P     1 
ATOM 4247 O OP1   . U   B 2 79  ? 132.386 123.129 173.918 1.00 144.05 ? 79  U   B OP1   1 
ATOM 4248 O OP2   . U   B 2 79  ? 132.055 125.676 173.897 1.00 146.66 ? 79  U   B OP2   1 
ATOM 4249 O "O5'" . U   B 2 79  ? 134.333 124.681 173.817 1.00 153.49 ? 79  U   B "O5'" 1 
ATOM 4250 C "C5'" . U   B 2 79  ? 134.941 125.966 173.728 1.00 151.96 ? 79  U   B "C5'" 1 
ATOM 4251 C "C4'" . U   B 2 79  ? 136.442 125.898 173.888 1.00 154.69 ? 79  U   B "C4'" 1 
ATOM 4252 O "O4'" . U   B 2 79  ? 136.766 125.202 175.123 1.00 160.47 ? 79  U   B "O4'" 1 
ATOM 4253 C "C3'" . U   B 2 79  ? 137.191 125.167 172.775 1.00 153.52 ? 79  U   B "C3'" 1 
ATOM 4254 O "O3'" . U   B 2 79  ? 138.445 125.807 172.543 1.00 155.34 ? 79  U   B "O3'" 1 
ATOM 4255 C "C2'" . U   B 2 79  ? 137.429 123.784 173.374 1.00 158.02 ? 79  U   B "C2'" 1 
ATOM 4256 O "O2'" . U   B 2 79  ? 138.537 123.094 172.835 1.00 160.15 ? 79  U   B "O2'" 1 
ATOM 4257 C "C1'" . U   B 2 79  ? 137.632 124.118 174.848 1.00 161.68 ? 79  U   B "C1'" 1 
ATOM 4258 N N1    . U   B 2 79  ? 137.292 123.016 175.759 1.00 162.41 ? 79  U   B N1    1 
ATOM 4259 C C2    . U   B 2 79  ? 138.321 122.413 176.456 1.00 161.37 ? 79  U   B C2    1 
ATOM 4260 O O2    . U   B 2 79  ? 139.485 122.757 176.346 1.00 160.18 ? 79  U   B O2    1 
ATOM 4261 N N3    . U   B 2 79  ? 137.935 121.392 177.289 1.00 163.79 ? 79  U   B N3    1 
ATOM 4262 C C4    . U   B 2 79  ? 136.652 120.923 177.489 1.00 167.46 ? 79  U   B C4    1 
ATOM 4263 O O4    . U   B 2 79  ? 136.463 119.993 178.274 1.00 171.32 ? 79  U   B O4    1 
ATOM 4264 C C5    . U   B 2 79  ? 135.645 121.600 176.730 1.00 163.64 ? 79  U   B C5    1 
ATOM 4265 C C6    . U   B 2 79  ? 135.991 122.598 175.911 1.00 161.14 ? 79  U   B C6    1 
ATOM 4266 P P     . A   B 2 80  ? 138.828 126.315 171.067 1.00 144.69 ? 80  A   B P     1 
ATOM 4267 O OP1   . A   B 2 80  ? 140.291 126.141 170.882 1.00 139.79 ? 80  A   B OP1   1 
ATOM 4268 O OP2   . A   B 2 80  ? 138.215 127.653 170.865 1.00 135.72 ? 80  A   B OP2   1 
ATOM 4269 O "O5'" . A   B 2 80  ? 138.085 125.288 170.103 1.00 134.31 ? 80  A   B "O5'" 1 
ATOM 4270 C "C5'" . A   B 2 80  ? 138.738 124.116 169.636 1.00 132.20 ? 80  A   B "C5'" 1 
ATOM 4271 C "C4'" . A   B 2 80  ? 138.477 123.903 168.169 1.00 127.66 ? 80  A   B "C4'" 1 
ATOM 4272 O "O4'" . A   B 2 80  ? 137.055 123.719 167.948 1.00 124.24 ? 80  A   B "O4'" 1 
ATOM 4273 C "C3'" . A   B 2 80  ? 138.846 125.067 167.266 1.00 123.28 ? 80  A   B "C3'" 1 
ATOM 4274 O "O3'" . A   B 2 80  ? 140.225 125.082 166.941 1.00 126.98 ? 80  A   B "O3'" 1 
ATOM 4275 C "C2'" . A   B 2 80  ? 137.932 124.867 166.066 1.00 116.82 ? 80  A   B "C2'" 1 
ATOM 4276 O "O2'" . A   B 2 80  ? 138.458 123.871 165.200 1.00 118.76 ? 80  A   B "O2'" 1 
ATOM 4277 C "C1'" . A   B 2 80  ? 136.673 124.313 166.727 1.00 116.15 ? 80  A   B "C1'" 1 
ATOM 4278 N N9    . A   B 2 80  ? 135.666 125.354 167.012 1.00 111.19 ? 80  A   B N9    1 
ATOM 4279 C C8    . A   B 2 80  ? 135.513 126.054 168.182 1.00 115.57 ? 80  A   B C8    1 
ATOM 4280 N N7    . A   B 2 80  ? 134.519 126.908 168.164 1.00 112.13 ? 80  A   B N7    1 
ATOM 4281 C C5    . A   B 2 80  ? 133.973 126.759 166.898 1.00 108.25 ? 80  A   B C5    1 
ATOM 4282 C C6    . A   B 2 80  ? 132.888 127.383 166.253 1.00 105.62 ? 80  A   B C6    1 
ATOM 4283 N N6    . A   B 2 80  ? 132.126 128.323 166.816 1.00 103.88 ? 80  A   B N6    1 
ATOM 4284 N N1    . A   B 2 80  ? 132.600 127.009 164.986 1.00 103.61 ? 80  A   B N1    1 
ATOM 4285 C C2    . A   B 2 80  ? 133.361 126.066 164.413 1.00 104.49 ? 80  A   B C2    1 
ATOM 4286 N N3    . A   B 2 80  ? 134.406 125.407 164.918 1.00 108.18 ? 80  A   B N3    1 
ATOM 4287 C C4    . A   B 2 80  ? 134.666 125.802 166.178 1.00 108.68 ? 80  A   B C4    1 
ATOM 4288 P P     . U   B 2 81  ? 140.843 126.286 166.078 1.00 121.76 ? 81  U   B P     1 
ATOM 4289 O OP1   . U   B 2 81  ? 142.294 126.364 166.384 1.00 120.58 ? 81  U   B OP1   1 
ATOM 4290 O OP2   . U   B 2 81  ? 139.989 127.485 166.265 1.00 113.07 ? 81  U   B OP2   1 
ATOM 4291 O "O5'" . U   B 2 81  ? 140.678 125.795 164.573 1.00 117.54 ? 81  U   B "O5'" 1 
ATOM 4292 C "C5'" . U   B 2 81  ? 140.597 126.732 163.514 1.00 113.62 ? 81  U   B "C5'" 1 
ATOM 4293 C "C4'" . U   B 2 81  ? 139.606 126.303 162.461 1.00 108.92 ? 81  U   B "C4'" 1 
ATOM 4294 O "O4'" . U   B 2 81  ? 138.318 126.025 163.069 1.00 105.77 ? 81  U   B "O4'" 1 
ATOM 4295 C "C3'" . U   B 2 81  ? 139.304 127.346 161.400 1.00 102.20 ? 81  U   B "C3'" 1 
ATOM 4296 O "O3'" . U   B 2 81  ? 140.275 127.356 160.371 1.00 103.35 ? 81  U   B "O3'" 1 
ATOM 4297 C "C2'" . U   B 2 81  ? 137.915 126.953 160.922 1.00 99.09  ? 81  U   B "C2'" 1 
ATOM 4298 O "O2'" . U   B 2 81  ? 137.991 125.872 160.005 1.00 104.81 ? 81  U   B "O2'" 1 
ATOM 4299 C "C1'" . U   B 2 81  ? 137.275 126.439 162.212 1.00 98.82  ? 81  U   B "C1'" 1 
ATOM 4300 N N1    . U   B 2 81  ? 136.466 127.458 162.930 1.00 96.66  ? 81  U   B N1    1 
ATOM 4301 C C2    . U   B 2 81  ? 135.342 128.072 162.382 1.00 92.52  ? 81  U   B C2    1 
ATOM 4302 O O2    . U   B 2 81  ? 134.924 127.900 161.251 1.00 92.25  ? 81  U   B O2    1 
ATOM 4303 N N3    . U   B 2 81  ? 134.723 128.983 163.210 1.00 92.68  ? 81  U   B N3    1 
ATOM 4304 C C4    . U   B 2 81  ? 135.058 129.312 164.505 1.00 95.75  ? 81  U   B C4    1 
ATOM 4305 O O4    . U   B 2 81  ? 134.404 130.139 165.137 1.00 93.16  ? 81  U   B O4    1 
ATOM 4306 C C5    . U   B 2 81  ? 136.199 128.622 165.004 1.00 100.55 ? 81  U   B C5    1 
ATOM 4307 C C6    . U   B 2 81  ? 136.829 127.746 164.223 1.00 101.60 ? 81  U   B C6    1 
ATOM 4308 P P     . A   B 2 82  ? 140.914 128.741 159.873 1.00 107.49 ? 82  A   B P     1 
ATOM 4309 O OP1   . A   B 2 82  ? 142.136 128.424 159.093 1.00 111.65 ? 82  A   B OP1   1 
ATOM 4310 O OP2   . A   B 2 82  ? 140.996 129.661 161.034 1.00 105.36 ? 82  A   B OP2   1 
ATOM 4311 O "O5'" . A   B 2 82  ? 139.822 129.313 158.870 1.00 87.25  ? 82  A   B "O5'" 1 
ATOM 4312 C "C5'" . A   B 2 82  ? 139.278 128.490 157.846 1.00 81.40  ? 82  A   B "C5'" 1 
ATOM 4313 C "C4'" . A   B 2 82  ? 137.982 129.040 157.305 1.00 78.31  ? 82  A   B "C4'" 1 
ATOM 4314 O "O4'" . A   B 2 82  ? 137.028 129.210 158.388 1.00 81.83  ? 82  A   B "O4'" 1 
ATOM 4315 C "C3'" . A   B 2 82  ? 138.076 130.394 156.611 1.00 71.87  ? 82  A   B "C3'" 1 
ATOM 4316 O "O3'" . A   B 2 82  ? 137.113 130.423 155.567 1.00 65.14  ? 82  A   B "O3'" 1 
ATOM 4317 C "C2'" . A   B 2 82  ? 137.646 131.364 157.706 1.00 70.55  ? 82  A   B "C2'" 1 
ATOM 4318 O "O2'" . A   B 2 82  ? 137.141 132.593 157.234 1.00 70.31  ? 82  A   B "O2'" 1 
ATOM 4319 C "C1'" . A   B 2 82  ? 136.575 130.551 158.414 1.00 75.73  ? 82  A   B "C1'" 1 
ATOM 4320 N N9    . A   B 2 82  ? 136.348 130.919 159.810 1.00 82.49  ? 82  A   B N9    1 
ATOM 4321 C C8    . A   B 2 82  ? 136.977 130.395 160.905 1.00 88.47  ? 82  A   B C8    1 
ATOM 4322 N N7    . A   B 2 82  ? 136.558 130.886 162.045 1.00 90.28  ? 82  A   B N7    1 
ATOM 4323 C C5    . A   B 2 82  ? 135.578 131.786 161.668 1.00 83.92  ? 82  A   B C5    1 
ATOM 4324 C C6    . A   B 2 82  ? 134.751 132.638 162.413 1.00 84.20  ? 82  A   B C6    1 
ATOM 4325 N N6    . A   B 2 82  ? 134.786 132.713 163.746 1.00 91.44  ? 82  A   B N6    1 
ATOM 4326 N N1    . A   B 2 82  ? 133.881 133.416 161.735 1.00 78.17  ? 82  A   B N1    1 
ATOM 4327 C C2    . A   B 2 82  ? 133.848 133.330 160.401 1.00 77.37  ? 82  A   B C2    1 
ATOM 4328 N N3    . A   B 2 82  ? 134.578 132.571 159.589 1.00 76.13  ? 82  A   B N3    1 
ATOM 4329 C C4    . A   B 2 82  ? 135.430 131.813 160.295 1.00 80.02  ? 82  A   B C4    1 
ATOM 4330 P P     . C   B 2 83  ? 137.496 131.014 154.131 1.00 57.52  ? 83  C   B P     1 
ATOM 4331 O OP1   . C   B 2 83  ? 136.747 130.230 153.124 1.00 48.02  ? 83  C   B OP1   1 
ATOM 4332 O OP2   . C   B 2 83  ? 138.972 131.119 154.030 1.00 52.78  ? 83  C   B OP2   1 
ATOM 4333 O "O5'" . C   B 2 83  ? 136.885 132.480 154.162 1.00 50.55  ? 83  C   B "O5'" 1 
ATOM 4334 C "C5'" . C   B 2 83  ? 136.854 133.288 152.995 1.00 44.27  ? 83  C   B "C5'" 1 
ATOM 4335 C "C4'" . C   B 2 83  ? 135.603 134.125 152.932 1.00 41.98  ? 83  C   B "C4'" 1 
ATOM 4336 O "O4'" . C   B 2 83  ? 134.521 133.341 152.365 1.00 42.28  ? 83  C   B "O4'" 1 
ATOM 4337 C "C3'" . C   B 2 83  ? 135.098 134.654 154.272 1.00 43.10  ? 83  C   B "C3'" 1 
ATOM 4338 O "O3'" . C   B 2 83  ? 134.609 135.977 154.103 1.00 47.17  ? 83  C   B "O3'" 1 
ATOM 4339 C "C2'" . C   B 2 83  ? 133.941 133.714 154.606 1.00 44.07  ? 83  C   B "C2'" 1 
ATOM 4340 O "O2'" . C   B 2 83  ? 132.945 134.276 155.434 1.00 47.95  ? 83  C   B "O2'" 1 
ATOM 4341 C "C1'" . C   B 2 83  ? 133.399 133.377 153.223 1.00 40.07  ? 83  C   B "C1'" 1 
ATOM 4342 N N1    . C   B 2 83  ? 132.738 132.069 153.155 1.00 37.04  ? 83  C   B N1    1 
ATOM 4343 C C2    . C   B 2 83  ? 131.369 132.011 152.916 1.00 38.34  ? 83  C   B C2    1 
ATOM 4344 O O2    . C   B 2 83  ? 130.748 133.069 152.769 1.00 38.65  ? 83  C   B O2    1 
ATOM 4345 N N3    . C   B 2 83  ? 130.760 130.808 152.853 1.00 40.20  ? 83  C   B N3    1 
ATOM 4346 C C4    . C   B 2 83  ? 131.471 129.694 153.019 1.00 39.90  ? 83  C   B C4    1 
ATOM 4347 N N4    . C   B 2 83  ? 130.833 128.524 152.950 1.00 37.78  ? 83  C   B N4    1 
ATOM 4348 C C5    . C   B 2 83  ? 132.871 129.724 153.263 1.00 38.17  ? 83  C   B C5    1 
ATOM 4349 C C6    . C   B 2 83  ? 133.457 130.924 153.322 1.00 38.89  ? 83  C   B C6    1 
ATOM 4350 P P     . G   B 2 84  ? 135.449 137.205 154.697 1.00 52.68  ? 84  G   B P     1 
ATOM 4351 O OP1   . G   B 2 84  ? 134.915 138.456 154.112 1.00 52.38  ? 84  G   B OP1   1 
ATOM 4352 O OP2   . G   B 2 84  ? 136.888 136.881 154.550 1.00 55.41  ? 84  G   B OP2   1 
ATOM 4353 O "O5'" . G   B 2 84  ? 135.108 137.176 156.250 1.00 57.31  ? 84  G   B "O5'" 1 
ATOM 4354 C "C5'" . G   B 2 84  ? 133.787 137.412 156.711 1.00 57.61  ? 84  G   B "C5'" 1 
ATOM 4355 C "C4'" . G   B 2 84  ? 133.766 137.673 158.193 1.00 55.35  ? 84  G   B "C4'" 1 
ATOM 4356 O "O4'" . G   B 2 84  ? 134.056 136.452 158.910 1.00 55.10  ? 84  G   B "O4'" 1 
ATOM 4357 C "C3'" . G   B 2 84  ? 134.804 138.661 158.694 1.00 58.99  ? 84  G   B "C3'" 1 
ATOM 4358 O "O3'" . G   B 2 84  ? 134.371 140.001 158.542 1.00 59.24  ? 84  G   B "O3'" 1 
ATOM 4359 C "C2'" . G   B 2 84  ? 134.999 138.251 160.149 1.00 65.27  ? 84  G   B "C2'" 1 
ATOM 4360 O "O2'" . G   B 2 84  ? 133.996 138.831 160.968 1.00 72.51  ? 84  G   B "O2'" 1 
ATOM 4361 C "C1'" . G   B 2 84  ? 134.759 136.743 160.094 1.00 64.00  ? 84  G   B "C1'" 1 
ATOM 4362 N N9    . G   B 2 84  ? 135.983 135.916 160.131 1.00 69.44  ? 84  G   B N9    1 
ATOM 4363 C C8    . G   B 2 84  ? 136.369 135.070 159.125 1.00 71.72  ? 84  G   B C8    1 
ATOM 4364 N N7    . G   B 2 84  ? 137.451 134.400 159.389 1.00 74.94  ? 84  G   B N7    1 
ATOM 4365 C C5    . G   B 2 84  ? 137.809 134.821 160.657 1.00 79.08  ? 84  G   B C5    1 
ATOM 4366 C C6    . G   B 2 84  ? 138.919 134.434 161.449 1.00 85.48  ? 84  G   B C6    1 
ATOM 4367 O O6    . G   B 2 84  ? 139.806 133.619 161.168 1.00 87.67  ? 84  G   B O6    1 
ATOM 4368 N N1    . G   B 2 84  ? 138.933 135.088 162.675 1.00 85.56  ? 84  G   B N1    1 
ATOM 4369 C C2    . G   B 2 84  ? 137.987 136.002 163.075 1.00 81.68  ? 84  G   B C2    1 
ATOM 4370 N N2    . G   B 2 84  ? 138.178 136.527 164.296 1.00 84.30  ? 84  G   B N2    1 
ATOM 4371 N N3    . G   B 2 84  ? 136.944 136.375 162.341 1.00 78.63  ? 84  G   B N3    1 
ATOM 4372 C C4    . G   B 2 84  ? 136.906 135.743 161.146 1.00 76.06  ? 84  G   B C4    1 
ATOM 4373 P P     . C   B 2 85  ? 135.430 141.182 158.300 1.00 71.69  ? 85  C   B P     1 
ATOM 4374 O OP1   . C   B 2 85  ? 134.663 142.410 157.981 1.00 69.24  ? 85  C   B OP1   1 
ATOM 4375 O OP2   . C   B 2 85  ? 136.467 140.705 157.354 1.00 63.76  ? 85  C   B OP2   1 
ATOM 4376 O "O5'" . C   B 2 85  ? 136.106 141.386 159.727 1.00 73.14  ? 85  C   B "O5'" 1 
ATOM 4377 C "C5'" . C   B 2 85  ? 135.370 141.925 160.814 1.00 68.93  ? 85  C   B "C5'" 1 
ATOM 4378 C "C4'" . C   B 2 85  ? 136.215 142.004 162.059 1.00 68.92  ? 85  C   B "C4'" 1 
ATOM 4379 O "O4'" . C   B 2 85  ? 136.583 140.670 162.484 1.00 71.09  ? 85  C   B "O4'" 1 
ATOM 4380 C "C3'" . C   B 2 85  ? 137.541 142.727 161.903 1.00 72.54  ? 85  C   B "C3'" 1 
ATOM 4381 O "O3'" . C   B 2 85  ? 137.396 144.130 162.028 1.00 76.38  ? 85  C   B "O3'" 1 
ATOM 4382 C "C2'" . C   B 2 85  ? 138.403 142.110 162.997 1.00 79.73  ? 85  C   B "C2'" 1 
ATOM 4383 O "O2'" . C   B 2 85  ? 138.141 142.730 164.247 1.00 86.08  ? 85  C   B "O2'" 1 
ATOM 4384 C "C1'" . C   B 2 85  ? 137.872 140.679 163.052 1.00 76.26  ? 85  C   B "C1'" 1 
ATOM 4385 N N1    . C   B 2 85  ? 138.705 139.684 162.337 1.00 75.84  ? 85  C   B N1    1 
ATOM 4386 C C2    . C   B 2 85  ? 139.908 139.190 162.861 1.00 83.47  ? 85  C   B C2    1 
ATOM 4387 O O2    . C   B 2 85  ? 140.348 139.629 163.935 1.00 87.38  ? 85  C   B O2    1 
ATOM 4388 N N3    . C   B 2 85  ? 140.587 138.248 162.157 1.00 83.31  ? 85  C   B N3    1 
ATOM 4389 C C4    . C   B 2 85  ? 140.104 137.789 161.002 1.00 78.62  ? 85  C   B C4    1 
ATOM 4390 N N4    . C   B 2 85  ? 140.787 136.863 160.331 1.00 81.14  ? 85  C   B N4    1 
ATOM 4391 C C5    . C   B 2 85  ? 138.885 138.264 160.463 1.00 71.84  ? 85  C   B C5    1 
ATOM 4392 C C6    . C   B 2 85  ? 138.230 139.185 161.165 1.00 70.75  ? 85  C   B C6    1 
ATOM 4393 P P     . U   B 2 86  ? 138.321 145.124 161.175 1.00 94.07  ? 86  U   B P     1 
ATOM 4394 O OP1   . U   B 2 86  ? 137.862 146.508 161.448 1.00 92.70  ? 86  U   B OP1   1 
ATOM 4395 O OP2   . U   B 2 86  ? 138.372 144.625 159.780 1.00 94.20  ? 86  U   B OP2   1 
ATOM 4396 O "O5'" . U   B 2 86  ? 139.766 144.956 161.823 1.00 89.25  ? 86  U   B "O5'" 1 
ATOM 4397 C "C5'" . U   B 2 86  ? 140.024 145.398 163.147 1.00 86.80  ? 86  U   B "C5'" 1 
ATOM 4398 C "C4'" . U   B 2 86  ? 141.396 144.984 163.610 1.00 85.08  ? 86  U   B "C4'" 1 
ATOM 4399 O "O4'" . U   B 2 86  ? 141.462 143.544 163.753 1.00 81.75  ? 86  U   B "O4'" 1 
ATOM 4400 C "C3'" . U   B 2 86  ? 142.541 145.308 162.669 1.00 87.15  ? 86  U   B "C3'" 1 
ATOM 4401 O "O3'" . U   B 2 86  ? 142.958 146.659 162.760 1.00 89.97  ? 86  U   B "O3'" 1 
ATOM 4402 C "C2'" . U   B 2 86  ? 143.612 144.313 163.093 1.00 87.36  ? 86  U   B "C2'" 1 
ATOM 4403 O "O2'" . U   B 2 86  ? 144.287 144.771 164.255 1.00 90.50  ? 86  U   B "O2'" 1 
ATOM 4404 C "C1'" . U   B 2 86  ? 142.772 143.096 163.476 1.00 82.05  ? 86  U   B "C1'" 1 
ATOM 4405 N N1    . U   B 2 86  ? 142.721 142.066 162.412 1.00 80.59  ? 86  U   B N1    1 
ATOM 4406 C C2    . U   B 2 86  ? 143.779 141.180 162.306 1.00 82.64  ? 86  U   B C2    1 
ATOM 4407 O O2    . U   B 2 86  ? 144.752 141.222 163.036 1.00 84.82  ? 86  U   B O2    1 
ATOM 4408 N N3    . U   B 2 86  ? 143.661 140.241 161.310 1.00 83.16  ? 86  U   B N3    1 
ATOM 4409 C C4    . U   B 2 86  ? 142.604 140.106 160.432 1.00 83.66  ? 86  U   B C4    1 
ATOM 4410 O O4    . U   B 2 86  ? 142.614 139.219 159.580 1.00 86.48  ? 86  U   B O4    1 
ATOM 4411 C C5    . U   B 2 86  ? 141.552 141.056 160.609 1.00 81.72  ? 86  U   B C5    1 
ATOM 4412 C C6    . U   B 2 86  ? 141.644 141.975 161.569 1.00 79.90  ? 86  U   B C6    1 
ATOM 4413 P P     . U   B 2 87  ? 143.424 147.453 161.444 1.00 95.61  ? 87  U   B P     1 
ATOM 4414 O OP1   . U   B 2 87  ? 143.681 148.861 161.833 1.00 99.38  ? 87  U   B OP1   1 
ATOM 4415 O OP2   . U   B 2 87  ? 142.455 147.160 160.359 1.00 90.28  ? 87  U   B OP2   1 
ATOM 4416 O "O5'" . U   B 2 87  ? 144.822 146.789 161.069 1.00 90.40  ? 87  U   B "O5'" 1 
ATOM 4417 C "C5'" . U   B 2 87  ? 145.938 146.910 161.938 1.00 89.23  ? 87  U   B "C5'" 1 
ATOM 4418 C "C4'" . U   B 2 87  ? 147.018 145.917 161.594 1.00 85.55  ? 87  U   B "C4'" 1 
ATOM 4419 O "O4'" . U   B 2 87  ? 146.489 144.567 161.662 1.00 83.58  ? 87  U   B "O4'" 1 
ATOM 4420 C "C3'" . U   B 2 87  ? 147.588 146.018 160.191 1.00 82.13  ? 87  U   B "C3'" 1 
ATOM 4421 O "O3'" . U   B 2 87  ? 148.550 147.047 160.061 1.00 83.37  ? 87  U   B "O3'" 1 
ATOM 4422 C "C2'" . U   B 2 87  ? 148.142 144.618 159.958 1.00 82.91  ? 87  U   B "C2'" 1 
ATOM 4423 O "O2'" . U   B 2 87  ? 149.394 144.461 160.609 1.00 85.90  ? 87  U   B "O2'" 1 
ATOM 4424 C "C1'" . U   B 2 87  ? 147.107 143.757 160.685 1.00 81.92  ? 87  U   B "C1'" 1 
ATOM 4425 N N1    . U   B 2 87  ? 146.066 143.236 159.767 1.00 80.67  ? 87  U   B N1    1 
ATOM 4426 C C2    . U   B 2 87  ? 146.353 142.092 159.043 1.00 78.15  ? 87  U   B C2    1 
ATOM 4427 O O2    . U   B 2 87  ? 147.410 141.490 159.125 1.00 75.57  ? 87  U   B O2    1 
ATOM 4428 N N3    . U   B 2 87  ? 145.348 141.670 158.210 1.00 76.91  ? 87  U   B N3    1 
ATOM 4429 C C4    . U   B 2 87  ? 144.112 142.256 158.026 1.00 75.89  ? 87  U   B C4    1 
ATOM 4430 O O4    . U   B 2 87  ? 143.313 141.754 157.236 1.00 74.84  ? 87  U   B O4    1 
ATOM 4431 C C5    . U   B 2 87  ? 143.888 143.430 158.805 1.00 78.13  ? 87  U   B C5    1 
ATOM 4432 C C6    . U   B 2 87  ? 144.847 143.863 159.627 1.00 80.12  ? 87  U   B C6    1 
ATOM 4433 P P     . G   B 2 88  ? 148.767 147.767 158.644 1.00 88.36  ? 88  G   B P     1 
ATOM 4434 O OP1   . G   B 2 88  ? 149.402 149.086 158.888 1.00 90.92  ? 88  G   B OP1   1 
ATOM 4435 O OP2   . G   B 2 88  ? 147.492 147.695 157.889 1.00 87.83  ? 88  G   B OP2   1 
ATOM 4436 O "O5'" . G   B 2 88  ? 149.826 146.834 157.910 1.00 84.15  ? 88  G   B "O5'" 1 
ATOM 4437 C "C5'" . G   B 2 88  ? 149.609 146.389 156.582 1.00 78.05  ? 88  G   B "C5'" 1 
ATOM 4438 C "C4'" . G   B 2 88  ? 150.440 145.170 156.275 1.00 75.42  ? 88  G   B "C4'" 1 
ATOM 4439 O "O4'" . G   B 2 88  ? 149.859 144.006 156.919 1.00 73.30  ? 88  G   B "O4'" 1 
ATOM 4440 C "C3'" . G   B 2 88  ? 150.521 144.771 154.812 1.00 73.86  ? 88  G   B "C3'" 1 
ATOM 4441 O "O3'" . G   B 2 88  ? 151.452 145.537 154.070 1.00 75.13  ? 88  G   B "O3'" 1 
ATOM 4442 C "C2'" . G   B 2 88  ? 150.867 143.294 154.899 1.00 72.08  ? 88  G   B "C2'" 1 
ATOM 4443 O "O2'" . G   B 2 88  ? 152.233 143.119 155.242 1.00 69.68  ? 88  G   B "O2'" 1 
ATOM 4444 C "C1'" . G   B 2 88  ? 150.018 142.872 156.093 1.00 71.93  ? 88  G   B "C1'" 1 
ATOM 4445 N N9    . G   B 2 88  ? 148.682 142.414 155.673 1.00 69.75  ? 88  G   B N9    1 
ATOM 4446 C C8    . G   B 2 88  ? 147.484 143.044 155.900 1.00 70.87  ? 88  G   B C8    1 
ATOM 4447 N N7    . G   B 2 88  ? 146.464 142.398 155.408 1.00 68.93  ? 88  G   B N7    1 
ATOM 4448 C C5    . G   B 2 88  ? 147.023 141.274 154.818 1.00 66.93  ? 88  G   B C5    1 
ATOM 4449 C C6    . G   B 2 88  ? 146.412 140.204 154.120 1.00 62.98  ? 88  G   B C6    1 
ATOM 4450 O O6    . G   B 2 88  ? 145.213 140.021 153.888 1.00 62.65  ? 88  G   B O6    1 
ATOM 4451 N N1    . G   B 2 88  ? 147.348 139.272 153.690 1.00 61.87  ? 88  G   B N1    1 
ATOM 4452 C C2    . G   B 2 88  ? 148.701 139.362 153.892 1.00 63.04  ? 88  G   B C2    1 
ATOM 4453 N N2    . G   B 2 88  ? 149.443 138.360 153.400 1.00 62.34  ? 88  G   B N2    1 
ATOM 4454 N N3    . G   B 2 88  ? 149.282 140.353 154.542 1.00 65.91  ? 88  G   B N3    1 
ATOM 4455 C C4    . G   B 2 88  ? 148.390 141.268 154.973 1.00 67.16  ? 88  G   B C4    1 
ATOM 4456 P P     . G   B 2 89  ? 151.092 145.997 152.574 1.00 78.66  ? 89  G   B P     1 
ATOM 4457 O OP1   . G   B 2 89  ? 152.167 146.905 152.104 1.00 73.66  ? 89  G   B OP1   1 
ATOM 4458 O OP2   . G   B 2 89  ? 149.683 146.462 152.558 1.00 76.11  ? 89  G   B OP2   1 
ATOM 4459 O "O5'" . G   B 2 89  ? 151.176 144.650 151.731 1.00 69.87  ? 89  G   B "O5'" 1 
ATOM 4460 C "C5'" . G   B 2 89  ? 152.399 143.937 151.634 1.00 66.57  ? 89  G   B "C5'" 1 
ATOM 4461 C "C4'" . G   B 2 89  ? 152.204 142.559 151.055 1.00 61.21  ? 89  G   B "C4'" 1 
ATOM 4462 O "O4'" . G   B 2 89  ? 151.211 141.825 151.817 1.00 58.52  ? 89  G   B "O4'" 1 
ATOM 4463 C "C3'" . G   B 2 89  ? 151.682 142.492 149.633 1.00 56.99  ? 89  G   B "C3'" 1 
ATOM 4464 O "O3'" . G   B 2 89  ? 152.678 142.752 148.662 1.00 54.04  ? 89  G   B "O3'" 1 
ATOM 4465 C "C2'" . G   B 2 89  ? 151.119 141.081 149.565 1.00 58.36  ? 89  G   B "C2'" 1 
ATOM 4466 O "O2'" . G   B 2 89  ? 152.167 140.133 149.433 1.00 58.01  ? 89  G   B "O2'" 1 
ATOM 4467 C "C1'" . G   B 2 89  ? 150.520 140.935 150.963 1.00 55.99  ? 89  G   B "C1'" 1 
ATOM 4468 N N9    . G   B 2 89  ? 149.082 141.263 150.989 1.00 57.26  ? 89  G   B N9    1 
ATOM 4469 C C8    . G   B 2 89  ? 148.488 142.365 151.549 1.00 60.29  ? 89  G   B C8    1 
ATOM 4470 N N7    . G   B 2 89  ? 147.191 142.373 151.413 1.00 56.51  ? 89  G   B N7    1 
ATOM 4471 C C5    . G   B 2 89  ? 146.910 141.204 150.723 1.00 52.48  ? 89  G   B C5    1 
ATOM 4472 C C6    . G   B 2 89  ? 145.672 140.672 150.284 1.00 50.43  ? 89  G   B C6    1 
ATOM 4473 O O6    . G   B 2 89  ? 144.540 141.146 150.437 1.00 50.90  ? 89  G   B O6    1 
ATOM 4474 N N1    . G   B 2 89  ? 145.838 139.461 149.619 1.00 50.20  ? 89  G   B N1    1 
ATOM 4475 C C2    . G   B 2 89  ? 147.046 138.849 149.400 1.00 49.56  ? 89  G   B C2    1 
ATOM 4476 N N2    . G   B 2 89  ? 147.013 137.682 148.741 1.00 47.70  ? 89  G   B N2    1 
ATOM 4477 N N3    . G   B 2 89  ? 148.204 139.336 149.805 1.00 52.13  ? 89  G   B N3    1 
ATOM 4478 C C4    . G   B 2 89  ? 148.064 140.508 150.454 1.00 53.95  ? 89  G   B C4    1 
ATOM 4479 P P     . G   B 2 90  ? 152.274 143.434 147.268 1.00 55.07  ? 90  G   B P     1 
ATOM 4480 O OP1   . G   B 2 90  ? 153.524 143.810 146.564 1.00 49.44  ? 90  G   B OP1   1 
ATOM 4481 O OP2   . G   B 2 90  ? 151.243 144.466 147.535 1.00 54.78  ? 90  G   B OP2   1 
ATOM 4482 O "O5'" . G   B 2 90  ? 151.582 142.254 146.456 1.00 55.14  ? 90  G   B "O5'" 1 
ATOM 4483 C "C5'" . G   B 2 90  ? 152.332 141.133 146.014 1.00 55.47  ? 90  G   B "C5'" 1 
ATOM 4484 C "C4'" . G   B 2 90  ? 151.494 140.228 145.148 1.00 47.29  ? 90  G   B "C4'" 1 
ATOM 4485 O "O4'" . G   B 2 90  ? 150.469 139.600 145.955 1.00 36.30  ? 90  G   B "O4'" 1 
ATOM 4486 C "C3'" . G   B 2 90  ? 150.723 140.922 144.037 1.00 50.31  ? 90  G   B "C3'" 1 
ATOM 4487 O "O3'" . G   B 2 90  ? 151.506 141.131 142.878 1.00 48.35  ? 90  G   B "O3'" 1 
ATOM 4488 C "C2'" . G   B 2 90  ? 149.543 139.992 143.807 1.00 51.39  ? 90  G   B "C2'" 1 
ATOM 4489 O "O2'" . G   B 2 90  ? 149.931 138.882 143.012 1.00 56.46  ? 90  G   B "O2'" 1 
ATOM 4490 C "C1'" . G   B 2 90  ? 149.272 139.493 145.221 1.00 42.16  ? 90  G   B "C1'" 1 
ATOM 4491 N N9    . G   B 2 90  ? 148.232 140.268 145.922 1.00 44.11  ? 90  G   B N9    1 
ATOM 4492 C C8    . G   B 2 90  ? 148.427 141.242 146.866 1.00 46.45  ? 90  G   B C8    1 
ATOM 4493 N N7    . G   B 2 90  ? 147.314 141.733 147.337 1.00 46.99  ? 90  G   B N7    1 
ATOM 4494 C C5    . G   B 2 90  ? 146.323 141.033 146.669 1.00 47.30  ? 90  G   B C5    1 
ATOM 4495 C C6    . G   B 2 90  ? 144.913 141.129 146.756 1.00 48.65  ? 90  G   B C6    1 
ATOM 4496 O O6    . G   B 2 90  ? 144.236 141.871 147.476 1.00 49.79  ? 90  G   B O6    1 
ATOM 4497 N N1    . G   B 2 90  ? 144.286 140.231 145.901 1.00 45.67  ? 90  G   B N1    1 
ATOM 4498 C C2    . G   B 2 90  ? 144.938 139.360 145.068 1.00 43.14  ? 90  G   B C2    1 
ATOM 4499 N N2    . G   B 2 90  ? 144.176 138.568 144.310 1.00 41.43  ? 90  G   B N2    1 
ATOM 4500 N N3    . G   B 2 90  ? 146.249 139.263 144.975 1.00 45.54  ? 90  G   B N3    1 
ATOM 4501 C C4    . G   B 2 90  ? 146.874 140.123 145.797 1.00 46.72  ? 90  G   B C4    1 
ATOM 4502 P P     . U   B 2 91  ? 151.376 142.508 142.070 1.00 46.65  ? 91  U   B P     1 
ATOM 4503 O OP1   . U   B 2 91  ? 152.423 142.515 141.021 1.00 54.29  ? 91  U   B OP1   1 
ATOM 4504 O OP2   . U   B 2 91  ? 151.330 143.596 143.074 1.00 52.79  ? 91  U   B OP2   1 
ATOM 4505 O "O5'" . U   B 2 91  ? 149.954 142.405 141.360 1.00 54.48  ? 91  U   B "O5'" 1 
ATOM 4506 C "C5'" . U   B 2 91  ? 149.723 141.439 140.346 1.00 53.64  ? 91  U   B "C5'" 1 
ATOM 4507 C "C4'" . U   B 2 91  ? 148.253 141.240 140.070 1.00 48.73  ? 91  U   B "C4'" 1 
ATOM 4508 O "O4'" . U   B 2 91  ? 147.556 140.958 141.305 1.00 43.58  ? 91  U   B "O4'" 1 
ATOM 4509 C "C3'" . U   B 2 91  ? 147.514 142.433 139.489 1.00 53.42  ? 91  U   B "C3'" 1 
ATOM 4510 O "O3'" . U   B 2 91  ? 147.676 142.537 138.087 1.00 54.17  ? 91  U   B "O3'" 1 
ATOM 4511 C "C2'" . U   B 2 91  ? 146.070 142.181 139.906 1.00 48.67  ? 91  U   B "C2'" 1 
ATOM 4512 O "O2'" . U   B 2 91  ? 145.442 141.279 139.009 1.00 48.77  ? 91  U   B "O2'" 1 
ATOM 4513 C "C1'" . U   B 2 91  ? 146.247 141.476 141.250 1.00 46.74  ? 91  U   B "C1'" 1 
ATOM 4514 N N1    . U   B 2 91  ? 146.032 142.365 142.413 1.00 47.90  ? 91  U   B N1    1 
ATOM 4515 C C2    . U   B 2 91  ? 144.741 142.487 142.872 1.00 51.69  ? 91  U   B C2    1 
ATOM 4516 O O2    . U   B 2 91  ? 143.804 141.917 142.348 1.00 54.66  ? 91  U   B O2    1 
ATOM 4517 N N3    . U   B 2 91  ? 144.580 143.301 143.962 1.00 50.65  ? 91  U   B N3    1 
ATOM 4518 C C4    . U   B 2 91  ? 145.566 143.990 144.630 1.00 53.27  ? 91  U   B C4    1 
ATOM 4519 O O4    . U   B 2 91  ? 145.265 144.686 145.599 1.00 55.42  ? 91  U   B O4    1 
ATOM 4520 C C5    . U   B 2 91  ? 146.878 143.808 144.099 1.00 54.77  ? 91  U   B C5    1 
ATOM 4521 C C6    . U   B 2 91  ? 147.063 143.018 143.038 1.00 50.85  ? 91  U   B C6    1 
ATOM 4522 P P     . U   B 2 92  ? 147.708 143.978 137.384 1.00 65.80  ? 92  U   B P     1 
ATOM 4523 O OP1   . U   B 2 92  ? 146.354 144.578 137.464 1.00 66.88  ? 92  U   B OP1   1 
ATOM 4524 O OP2   . U   B 2 92  ? 148.373 143.826 136.068 1.00 73.10  ? 92  U   B OP2   1 
ATOM 4525 O "O5'" . U   B 2 92  ? 148.661 144.831 138.326 1.00 64.30  ? 92  U   B "O5'" 1 
ATOM 4526 C "C5'" . U   B 2 92  ? 148.955 146.188 138.028 1.00 73.98  ? 92  U   B "C5'" 1 
ATOM 4527 C "C4'" . U   B 2 92  ? 149.736 146.839 139.140 1.00 76.36  ? 92  U   B "C4'" 1 
ATOM 4528 O "O4'" . U   B 2 92  ? 148.813 147.573 139.986 1.00 77.81  ? 92  U   B "O4'" 1 
ATOM 4529 C "C3'" . U   B 2 92  ? 150.501 145.874 140.047 1.00 75.42  ? 92  U   B "C3'" 1 
ATOM 4530 O "O3'" . U   B 2 92  ? 151.892 146.231 140.253 1.00 80.98  ? 92  U   B "O3'" 1 
ATOM 4531 C "C2'" . U   B 2 92  ? 149.667 145.829 141.334 1.00 72.39  ? 92  U   B "C2'" 1 
ATOM 4532 O "O2'" . U   B 2 92  ? 150.414 145.625 142.513 1.00 69.34  ? 92  U   B "O2'" 1 
ATOM 4533 C "C1'" . U   B 2 92  ? 148.967 147.188 141.336 1.00 78.54  ? 92  U   B "C1'" 1 
ATOM 4534 N N1    . U   B 2 92  ? 147.643 147.192 141.983 1.00 77.34  ? 92  U   B N1    1 
ATOM 4535 C C2    . U   B 2 92  ? 146.553 146.567 141.393 1.00 74.49  ? 92  U   B C2    1 
ATOM 4536 O O2    . U   B 2 92  ? 146.576 145.973 140.329 1.00 79.10  ? 92  U   B O2    1 
ATOM 4537 N N3    . U   B 2 92  ? 145.384 146.649 142.103 1.00 68.59  ? 92  U   B N3    1 
ATOM 4538 C C4    . U   B 2 92  ? 145.181 147.274 143.310 1.00 69.95  ? 92  U   B C4    1 
ATOM 4539 O O4    . U   B 2 92  ? 144.060 147.254 143.817 1.00 67.77  ? 92  U   B O4    1 
ATOM 4540 C C5    . U   B 2 92  ? 146.345 147.896 143.857 1.00 72.55  ? 92  U   B C5    1 
ATOM 4541 C C6    . U   B 2 92  ? 147.500 147.833 143.190 1.00 74.16  ? 92  U   B C6    1 
ATOM 4542 P P     . U   B 2 93  ? 152.470 147.632 140.829 1.00 95.83  ? 93  U   B P     1 
ATOM 4543 O OP1   . U   B 2 93  ? 153.937 147.431 140.787 1.00 92.10  ? 93  U   B OP1   1 
ATOM 4544 O OP2   . U   B 2 93  ? 151.904 148.039 142.136 1.00 93.35  ? 93  U   B OP2   1 
ATOM 4545 O "O5'" . U   B 2 93  ? 152.175 148.728 139.709 1.00 95.74  ? 93  U   B "O5'" 1 
ATOM 4546 C "C5'" . U   B 2 93  ? 153.125 148.997 138.683 1.00 99.07  ? 93  U   B "C5'" 1 
ATOM 4547 C "C4'" . U   B 2 93  ? 152.470 149.540 137.436 1.00 101.59 ? 93  U   B "C4'" 1 
ATOM 4548 O "O4'" . U   B 2 93  ? 151.051 149.241 137.480 1.00 100.59 ? 93  U   B "O4'" 1 
ATOM 4549 C "C3'" . U   B 2 93  ? 152.584 151.048 137.239 1.00 109.54 ? 93  U   B "C3'" 1 
ATOM 4550 O "O3'" . U   B 2 93  ? 152.709 151.345 135.851 1.00 114.28 ? 93  U   B "O3'" 1 
ATOM 4551 C "C2'" . U   B 2 93  ? 151.247 151.567 137.756 1.00 108.07 ? 93  U   B "C2'" 1 
ATOM 4552 O "O2'" . U   B 2 93  ? 150.840 152.795 137.190 1.00 108.07 ? 93  U   B "O2'" 1 
ATOM 4553 C "C1'" . U   B 2 93  ? 150.297 150.433 137.383 1.00 103.21 ? 93  U   B "C1'" 1 
ATOM 4554 N N1    . U   B 2 93  ? 149.152 150.312 138.299 1.00 99.08  ? 93  U   B N1    1 
ATOM 4555 C C2    . U   B 2 93  ? 147.976 149.779 137.814 1.00 93.82  ? 93  U   B C2    1 
ATOM 4556 O O2    . U   B 2 93  ? 147.852 149.393 136.666 1.00 93.96  ? 93  U   B O2    1 
ATOM 4557 N N3    . U   B 2 93  ? 146.955 149.702 138.727 1.00 89.30  ? 93  U   B N3    1 
ATOM 4558 C C4    . U   B 2 93  ? 146.985 150.103 140.046 1.00 89.56  ? 93  U   B C4    1 
ATOM 4559 O O4    . U   B 2 93  ? 145.980 149.971 140.745 1.00 89.69  ? 93  U   B O4    1 
ATOM 4560 C C5    . U   B 2 93  ? 148.233 150.654 140.471 1.00 91.21  ? 93  U   B C5    1 
ATOM 4561 C C6    . U   B 2 93  ? 149.246 150.736 139.604 1.00 95.30  ? 93  U   B C6    1 
ATOM 4562 P P     . G   B 2 94  ? 153.862 152.348 135.360 1.00 124.16 ? 94  G   B P     1 
ATOM 4563 O OP1   . G   B 2 94  ? 153.574 152.733 133.955 1.00 119.47 ? 94  G   B OP1   1 
ATOM 4564 O OP2   . G   B 2 94  ? 155.171 151.738 135.703 1.00 120.96 ? 94  G   B OP2   1 
ATOM 4565 O "O5'" . G   B 2 94  ? 153.655 153.634 136.278 1.00 119.56 ? 94  G   B "O5'" 1 
ATOM 4566 C "C5'" . G   B 2 94  ? 154.708 154.138 137.086 1.00 117.10 ? 94  G   B "C5'" 1 
ATOM 4567 C "C4'" . G   B 2 94  ? 154.249 155.322 137.898 1.00 115.79 ? 94  G   B "C4'" 1 
ATOM 4568 O "O4'" . G   B 2 94  ? 153.544 156.244 137.033 1.00 117.28 ? 94  G   B "O4'" 1 
ATOM 4569 C "C3'" . G   B 2 94  ? 153.261 155.020 139.018 1.00 112.74 ? 94  G   B "C3'" 1 
ATOM 4570 O "O3'" . G   B 2 94  ? 153.915 154.624 140.213 1.00 111.74 ? 94  G   B "O3'" 1 
ATOM 4571 C "C2'" . G   B 2 94  ? 152.492 156.328 139.164 1.00 113.57 ? 94  G   B "C2'" 1 
ATOM 4572 O "O2'" . G   B 2 94  ? 153.216 157.246 139.968 1.00 115.23 ? 94  G   B "O2'" 1 
ATOM 4573 C "C1'" . G   B 2 94  ? 152.481 156.852 137.729 1.00 115.77 ? 94  G   B "C1'" 1 
ATOM 4574 N N9    . G   B 2 94  ? 151.225 156.571 137.010 1.00 114.17 ? 94  G   B N9    1 
ATOM 4575 C C8    . G   B 2 94  ? 151.057 155.705 135.958 1.00 113.39 ? 94  G   B C8    1 
ATOM 4576 N N7    . G   B 2 94  ? 149.835 155.682 135.504 1.00 111.33 ? 94  G   B N7    1 
ATOM 4577 C C5    . G   B 2 94  ? 149.157 156.596 136.298 1.00 113.06 ? 94  G   B C5    1 
ATOM 4578 C C6    . G   B 2 94  ? 147.798 157.000 136.277 1.00 113.54 ? 94  G   B C6    1 
ATOM 4579 O O6    . G   B 2 94  ? 146.896 156.619 135.523 1.00 114.22 ? 94  G   B O6    1 
ATOM 4580 N N1    . G   B 2 94  ? 147.528 157.953 137.253 1.00 113.49 ? 94  G   B N1    1 
ATOM 4581 C C2    . G   B 2 94  ? 148.456 158.450 138.134 1.00 114.84 ? 94  G   B C2    1 
ATOM 4582 N N2    . G   B 2 94  ? 148.008 159.362 139.008 1.00 115.61 ? 94  G   B N2    1 
ATOM 4583 N N3    . G   B 2 94  ? 149.725 158.081 138.166 1.00 113.54 ? 94  G   B N3    1 
ATOM 4584 C C4    . G   B 2 94  ? 150.004 157.159 137.225 1.00 113.31 ? 94  G   B C4    1 
ATOM 4585 P P     . U   B 2 95  ? 153.175 153.699 141.301 1.00 116.08 ? 95  U   B P     1 
ATOM 4586 O OP1   . U   B 2 95  ? 154.160 153.390 142.365 1.00 112.66 ? 95  U   B OP1   1 
ATOM 4587 O OP2   . U   B 2 95  ? 152.502 152.586 140.594 1.00 109.41 ? 95  U   B OP2   1 
ATOM 4588 O "O5'" . U   B 2 95  ? 152.054 154.640 141.932 1.00 119.25 ? 95  U   B "O5'" 1 
ATOM 4589 C "C5'" . U   B 2 95  ? 152.396 155.687 142.828 1.00 115.39 ? 95  U   B "C5'" 1 
ATOM 4590 C "C4'" . U   B 2 95  ? 151.176 156.448 143.287 1.00 112.46 ? 95  U   B "C4'" 1 
ATOM 4591 O "O4'" . U   B 2 95  ? 150.527 157.071 142.150 1.00 111.83 ? 95  U   B "O4'" 1 
ATOM 4592 C "C3'" . U   B 2 95  ? 150.076 155.621 143.933 1.00 111.41 ? 95  U   B "C3'" 1 
ATOM 4593 O "O3'" . U   B 2 95  ? 150.334 155.336 145.297 1.00 115.01 ? 95  U   B "O3'" 1 
ATOM 4594 C "C2'" . U   B 2 95  ? 148.838 156.482 143.718 1.00 110.12 ? 95  U   B "C2'" 1 
ATOM 4595 O "O2'" . U   B 2 95  ? 148.777 157.519 144.685 1.00 113.00 ? 95  U   B "O2'" 1 
ATOM 4596 C "C1'" . U   B 2 95  ? 149.131 157.112 142.356 1.00 111.33 ? 95  U   B "C1'" 1 
ATOM 4597 N N1    . U   B 2 95  ? 148.456 156.410 141.238 1.00 111.47 ? 95  U   B N1    1 
ATOM 4598 C C2    . U   B 2 95  ? 147.122 156.693 141.010 1.00 108.53 ? 95  U   B C2    1 
ATOM 4599 O O2    . U   B 2 95  ? 146.481 157.475 141.691 1.00 105.90 ? 95  U   B O2    1 
ATOM 4600 N N3    . U   B 2 95  ? 146.549 156.024 139.957 1.00 107.93 ? 95  U   B N3    1 
ATOM 4601 C C4    . U   B 2 95  ? 147.173 155.122 139.118 1.00 105.55 ? 95  U   B C4    1 
ATOM 4602 O O4    . U   B 2 95  ? 146.536 154.595 138.206 1.00 106.21 ? 95  U   B O4    1 
ATOM 4603 C C5    . U   B 2 95  ? 148.552 154.886 139.412 1.00 105.50 ? 95  U   B C5    1 
ATOM 4604 C C6    . U   B 2 95  ? 149.131 155.524 140.432 1.00 109.97 ? 95  U   B C6    1 
ATOM 4605 P P     . C   B 2 96  ? 149.730 154.014 145.982 1.00 121.72 ? 96  C   B P     1 
ATOM 4606 O OP1   . C   B 2 96  ? 150.287 153.932 147.355 1.00 121.03 ? 96  C   B OP1   1 
ATOM 4607 O OP2   . C   B 2 96  ? 149.915 152.874 145.050 1.00 116.50 ? 96  C   B OP2   1 
ATOM 4608 O "O5'" . C   B 2 96  ? 148.170 154.318 146.110 1.00 112.83 ? 96  C   B "O5'" 1 
ATOM 4609 C "C5'" . C   B 2 96  ? 147.695 155.304 147.014 1.00 109.95 ? 96  C   B "C5'" 1 
ATOM 4610 C "C4'" . C   B 2 96  ? 146.202 155.489 146.909 1.00 105.43 ? 96  C   B "C4'" 1 
ATOM 4611 O "O4'" . C   B 2 96  ? 145.837 155.880 145.561 1.00 104.22 ? 96  C   B "O4'" 1 
ATOM 4612 C "C3'" . C   B 2 96  ? 145.353 154.258 147.172 1.00 101.40 ? 96  C   B "C3'" 1 
ATOM 4613 O "O3'" . C   B 2 96  ? 145.196 153.982 148.552 1.00 103.69 ? 96  C   B "O3'" 1 
ATOM 4614 C "C2'" . C   B 2 96  ? 144.047 154.598 146.463 1.00 97.17  ? 96  C   B "C2'" 1 
ATOM 4615 O "O2'" . C   B 2 96  ? 143.254 155.463 147.261 1.00 96.31  ? 96  C   B "O2'" 1 
ATOM 4616 C "C1'" . C   B 2 96  ? 144.549 155.386 145.251 1.00 99.09  ? 96  C   B "C1'" 1 
ATOM 4617 N N1    . C   B 2 96  ? 144.625 154.562 144.022 1.00 94.86  ? 96  C   B N1    1 
ATOM 4618 C C2    . C   B 2 96  ? 143.483 154.417 143.223 1.00 92.38  ? 96  C   B C2    1 
ATOM 4619 O O2    . C   B 2 96  ? 142.426 154.976 143.559 1.00 92.74  ? 96  C   B O2    1 
ATOM 4620 N N3    . C   B 2 96  ? 143.560 153.671 142.097 1.00 92.46  ? 96  C   B N3    1 
ATOM 4621 C C4    . C   B 2 96  ? 144.711 153.088 141.762 1.00 95.25  ? 96  C   B C4    1 
ATOM 4622 N N4    . C   B 2 96  ? 144.756 152.360 140.647 1.00 98.79  ? 96  C   B N4    1 
ATOM 4623 C C5    . C   B 2 96  ? 145.885 153.218 142.552 1.00 97.08  ? 96  C   B C5    1 
ATOM 4624 C C6    . C   B 2 96  ? 145.796 153.958 143.659 1.00 98.19  ? 96  C   B C6    1 
ATOM 4625 P P     . C   B 2 97  ? 144.731 152.522 149.031 1.00 103.37 ? 97  C   B P     1 
ATOM 4626 O OP1   . C   B 2 97  ? 145.006 152.405 150.485 1.00 105.75 ? 97  C   B OP1   1 
ATOM 4627 O OP2   . C   B 2 97  ? 145.302 151.523 148.094 1.00 100.35 ? 97  C   B OP2   1 
ATOM 4628 O "O5'" . C   B 2 97  ? 143.153 152.542 148.829 1.00 92.56  ? 97  C   B "O5'" 1 
ATOM 4629 C "C5'" . C   B 2 97  ? 142.472 151.417 148.301 1.00 85.72  ? 97  C   B "C5'" 1 
ATOM 4630 C "C4'" . C   B 2 97  ? 141.189 151.819 147.620 1.00 80.70  ? 97  C   B "C4'" 1 
ATOM 4631 O "O4'" . C   B 2 97  ? 141.474 152.351 146.300 1.00 82.71  ? 97  C   B "O4'" 1 
ATOM 4632 C "C3'" . C   B 2 97  ? 140.204 150.695 147.360 1.00 72.45  ? 97  C   B "C3'" 1 
ATOM 4633 O "O3'" . C   B 2 97  ? 139.434 150.379 148.505 1.00 72.40  ? 97  C   B "O3'" 1 
ATOM 4634 C "C2'" . C   B 2 97  ? 139.379 151.234 146.200 1.00 71.48  ? 97  C   B "C2'" 1 
ATOM 4635 O "O2'" . C   B 2 97  ? 138.408 152.159 146.666 1.00 71.63  ? 97  C   B "O2'" 1 
ATOM 4636 C "C1'" . C   B 2 97  ? 140.434 152.008 145.407 1.00 74.78  ? 97  C   B "C1'" 1 
ATOM 4637 N N1    . C   B 2 97  ? 141.015 151.238 144.276 1.00 73.71  ? 97  C   B N1    1 
ATOM 4638 C C2    . C   B 2 97  ? 140.283 150.953 143.110 1.00 74.41  ? 97  C   B C2    1 
ATOM 4639 O O2    . C   B 2 97  ? 139.102 151.313 143.000 1.00 75.00  ? 97  C   B O2    1 
ATOM 4640 N N3    . C   B 2 97  ? 140.872 150.260 142.105 1.00 75.26  ? 97  C   B N3    1 
ATOM 4641 C C4    . C   B 2 97  ? 142.142 149.874 142.213 1.00 75.14  ? 97  C   B C4    1 
ATOM 4642 N N4    . C   B 2 97  ? 142.684 149.200 141.198 1.00 75.46  ? 97  C   B N4    1 
ATOM 4643 C C5    . C   B 2 97  ? 142.913 150.160 143.370 1.00 76.14  ? 97  C   B C5    1 
ATOM 4644 C C6    . C   B 2 97  ? 142.318 150.836 144.356 1.00 76.98  ? 97  C   B C6    1 
ATOM 4645 P P     . A   B 2 98  ? 139.369 148.871 149.050 1.00 69.73  ? 98  A   B P     1 
ATOM 4646 O OP1   . A   B 2 98  ? 139.123 148.924 150.512 1.00 66.84  ? 98  A   B OP1   1 
ATOM 4647 O OP2   . A   B 2 98  ? 140.545 148.130 148.528 1.00 64.95  ? 98  A   B OP2   1 
ATOM 4648 O "O5'" . A   B 2 98  ? 138.066 148.283 148.354 1.00 68.89  ? 98  A   B "O5'" 1 
ATOM 4649 C "C5'" . A   B 2 98  ? 136.890 149.069 148.244 1.00 63.40  ? 98  A   B "C5'" 1 
ATOM 4650 C "C4'" . A   B 2 98  ? 136.102 148.704 147.013 1.00 59.59  ? 98  A   B "C4'" 1 
ATOM 4651 O "O4'" . A   B 2 98  ? 136.806 149.141 145.826 1.00 61.31  ? 98  A   B "O4'" 1 
ATOM 4652 C "C3'" . A   B 2 98  ? 135.882 147.219 146.787 1.00 55.30  ? 98  A   B "C3'" 1 
ATOM 4653 O "O3'" . A   B 2 98  ? 134.807 146.710 147.556 1.00 58.06  ? 98  A   B "O3'" 1 
ATOM 4654 C "C2'" . A   B 2 98  ? 135.643 147.139 145.285 1.00 54.70  ? 98  A   B "C2'" 1 
ATOM 4655 O "O2'" . A   B 2 98  ? 134.302 147.484 144.975 1.00 57.54  ? 98  A   B "O2'" 1 
ATOM 4656 C "C1'" . A   B 2 98  ? 136.557 148.248 144.763 1.00 56.53  ? 98  A   B "C1'" 1 
ATOM 4657 N N9    . A   B 2 98  ? 137.847 147.764 144.223 1.00 57.46  ? 98  A   B N9    1 
ATOM 4658 C C8    . A   B 2 98  ? 139.093 148.164 144.629 1.00 64.56  ? 98  A   B C8    1 
ATOM 4659 N N7    . A   B 2 98  ? 140.089 147.611 143.986 1.00 62.20  ? 98  A   B N7    1 
ATOM 4660 C C5    . A   B 2 98  ? 139.459 146.789 143.071 1.00 55.01  ? 98  A   B C5    1 
ATOM 4661 C C6    . A   B 2 98  ? 139.965 145.925 142.087 1.00 52.69  ? 98  A   B C6    1 
ATOM 4662 N N6    . A   B 2 98  ? 141.267 145.745 141.864 1.00 56.04  ? 98  A   B N6    1 
ATOM 4663 N N1    . A   B 2 98  ? 139.082 145.237 141.336 1.00 53.84  ? 98  A   B N1    1 
ATOM 4664 C C2    . A   B 2 98  ? 137.776 145.418 141.562 1.00 57.33  ? 98  A   B C2    1 
ATOM 4665 N N3    . A   B 2 98  ? 137.182 146.204 142.458 1.00 59.69  ? 98  A   B N3    1 
ATOM 4666 C C4    . A   B 2 98  ? 138.083 146.881 143.190 1.00 56.12  ? 98  A   B C4    1 
ATOM 4667 P P     . G   B 2 99  ? 134.960 145.327 148.354 1.00 64.35  ? 99  G   B P     1 
ATOM 4668 O OP1   . G   B 2 99  ? 133.705 145.112 149.115 1.00 67.19  ? 99  G   B OP1   1 
ATOM 4669 O OP2   . G   B 2 99  ? 136.261 145.325 149.065 1.00 61.30  ? 99  G   B OP2   1 
ATOM 4670 O "O5'" . G   B 2 99  ? 135.025 144.231 147.205 1.00 47.42  ? 99  G   B "O5'" 1 
ATOM 4671 C "C5'" . G   B 2 99  ? 133.918 144.015 146.344 1.00 47.54  ? 99  G   B "C5'" 1 
ATOM 4672 C "C4'" . G   B 2 99  ? 134.300 143.137 145.184 1.00 43.87  ? 99  G   B "C4'" 1 
ATOM 4673 O "O4'" . G   B 2 99  ? 135.208 143.851 144.308 1.00 47.29  ? 99  G   B "O4'" 1 
ATOM 4674 C "C3'" . G   B 2 99  ? 135.053 141.871 145.550 1.00 37.04  ? 99  G   B "C3'" 1 
ATOM 4675 O "O3'" . G   B 2 99  ? 134.189 140.828 145.957 1.00 37.69  ? 99  G   B "O3'" 1 
ATOM 4676 C "C2'" . G   B 2 99  ? 135.830 141.564 144.279 1.00 39.10  ? 99  G   B "C2'" 1 
ATOM 4677 O "O2'" . G   B 2 99  ? 134.990 140.951 143.315 1.00 43.11  ? 99  G   B "O2'" 1 
ATOM 4678 C "C1'" . G   B 2 99  ? 136.175 142.967 143.788 1.00 45.35  ? 99  G   B "C1'" 1 
ATOM 4679 N N9    . G   B 2 99  ? 137.506 143.427 144.235 1.00 51.14  ? 99  G   B N9    1 
ATOM 4680 C C8    . G   B 2 99  ? 137.722 144.395 145.178 1.00 52.92  ? 99  G   B C8    1 
ATOM 4681 N N7    . G   B 2 99  ? 138.978 144.658 145.389 1.00 52.85  ? 99  G   B N7    1 
ATOM 4682 C C5    . G   B 2 99  ? 139.644 143.799 144.535 1.00 48.74  ? 99  G   B C5    1 
ATOM 4683 C C6    . G   B 2 99  ? 141.032 143.628 144.334 1.00 50.20  ? 99  G   B C6    1 
ATOM 4684 O O6    . G   B 2 99  ? 141.965 144.219 144.888 1.00 56.49  ? 99  G   B O6    1 
ATOM 4685 N N1    . G   B 2 99  ? 141.292 142.656 143.381 1.00 43.45  ? 99  G   B N1    1 
ATOM 4686 C C2    . G   B 2 99  ? 140.338 141.944 142.709 1.00 41.86  ? 99  G   B C2    1 
ATOM 4687 N N2    . G   B 2 99  ? 140.798 141.050 141.825 1.00 42.28  ? 99  G   B N2    1 
ATOM 4688 N N3    . G   B 2 99  ? 139.036 142.094 142.886 1.00 46.21  ? 99  G   B N3    1 
ATOM 4689 C C4    . G   B 2 99  ? 138.757 143.036 143.807 1.00 47.58  ? 99  G   B C4    1 
ATOM 4690 P P     . C   B 2 100 ? 134.605 139.852 147.160 1.00 36.89  ? 100 C   B P     1 
ATOM 4691 O OP1   . C   B 2 100 ? 133.417 139.046 147.525 1.00 38.45  ? 100 C   B OP1   1 
ATOM 4692 O OP2   . C   B 2 100 ? 135.294 140.653 148.199 1.00 41.84  ? 100 C   B OP2   1 
ATOM 4693 O "O5'" . C   B 2 100 ? 135.666 138.874 146.495 1.00 34.34  ? 100 C   B "O5'" 1 
ATOM 4694 C "C5'" . C   B 2 100 ? 135.315 138.090 145.368 1.00 36.26  ? 100 C   B "C5'" 1 
ATOM 4695 C "C4'" . C   B 2 100 ? 136.535 137.529 144.689 1.00 33.34  ? 100 C   B "C4'" 1 
ATOM 4696 O "O4'" . C   B 2 100 ? 137.357 138.607 144.184 1.00 32.80  ? 100 C   B "O4'" 1 
ATOM 4697 C "C3'" . C   B 2 100 ? 137.468 136.734 145.582 1.00 30.87  ? 100 C   B "C3'" 1 
ATOM 4698 O "O3'" . C   B 2 100 ? 137.043 135.398 145.730 1.00 27.33  ? 100 C   B "O3'" 1 
ATOM 4699 C "C2'" . C   B 2 100 ? 138.804 136.853 144.870 1.00 32.99  ? 100 C   B "C2'" 1 
ATOM 4700 O "O2'" . C   B 2 100 ? 138.872 135.925 143.801 1.00 34.08  ? 100 C   B "O2'" 1 
ATOM 4701 C "C1'" . C   B 2 100 ? 138.720 138.260 144.281 1.00 35.98  ? 100 C   B "C1'" 1 
ATOM 4702 N N1    . C   B 2 100 ? 139.413 139.292 145.089 1.00 39.37  ? 100 C   B N1    1 
ATOM 4703 C C2    . C   B 2 100 ? 140.805 139.388 145.072 1.00 43.61  ? 100 C   B C2    1 
ATOM 4704 O O2    . C   B 2 100 ? 141.446 138.570 144.402 1.00 47.30  ? 100 C   B O2    1 
ATOM 4705 N N3    . C   B 2 100 ? 141.412 140.353 145.797 1.00 46.04  ? 100 C   B N3    1 
ATOM 4706 C C4    . C   B 2 100 ? 140.684 141.212 146.508 1.00 43.67  ? 100 C   B C4    1 
ATOM 4707 N N4    . C   B 2 100 ? 141.324 142.152 147.203 1.00 50.05  ? 100 C   B N4    1 
ATOM 4708 C C5    . C   B 2 100 ? 139.269 141.151 146.537 1.00 40.68  ? 100 C   B C5    1 
ATOM 4709 C C6    . C   B 2 100 ? 138.691 140.191 145.814 1.00 41.29  ? 100 C   B C6    1 
ATOM 4710 P P     . C   B 2 101 ? 137.387 134.580 147.060 1.00 30.21  ? 101 C   B P     1 
ATOM 4711 O OP1   . C   B 2 101 ? 136.807 133.235 146.856 1.00 34.79  ? 101 C   B OP1   1 
ATOM 4712 O OP2   . C   B 2 101 ? 137.032 135.401 148.241 1.00 29.55  ? 101 C   B OP2   1 
ATOM 4713 O "O5'" . C   B 2 101 ? 138.967 134.422 147.033 1.00 34.72  ? 101 C   B "O5'" 1 
ATOM 4714 C "C5'" . C   B 2 101 ? 139.579 133.456 146.196 1.00 36.01  ? 101 C   B "C5'" 1 
ATOM 4715 C "C4'" . C   B 2 101 ? 141.079 133.552 146.256 1.00 35.57  ? 101 C   B "C4'" 1 
ATOM 4716 O "O4'" . C   B 2 101 ? 141.506 134.878 145.856 1.00 38.69  ? 101 C   B "O4'" 1 
ATOM 4717 C "C3'" . C   B 2 101 ? 141.706 133.374 147.624 1.00 32.80  ? 101 C   B "C3'" 1 
ATOM 4718 O "O3'" . C   B 2 101 ? 141.805 132.019 148.018 1.00 30.01  ? 101 C   B "O3'" 1 
ATOM 4719 C "C2'" . C   B 2 101 ? 143.054 134.055 147.455 1.00 35.48  ? 101 C   B "C2'" 1 
ATOM 4720 O "O2'" . C   B 2 101 ? 143.953 133.204 146.763 1.00 40.47  ? 101 C   B "O2'" 1 
ATOM 4721 C "C1'" . C   B 2 101 ? 142.696 135.218 146.533 1.00 35.55  ? 101 C   B "C1'" 1 
ATOM 4722 N N1    . C   B 2 101 ? 142.499 136.491 147.261 1.00 33.58  ? 101 C   B N1    1 
ATOM 4723 C C2    . C   B 2 101 ? 143.622 137.237 147.619 1.00 41.00  ? 101 C   B C2    1 
ATOM 4724 O O2    . C   B 2 101 ? 144.749 136.811 147.331 1.00 44.36  ? 101 C   B O2    1 
ATOM 4725 N N3    . C   B 2 101 ? 143.464 138.409 148.275 1.00 46.91  ? 101 C   B N3    1 
ATOM 4726 C C4    . C   B 2 101 ? 142.240 138.843 148.567 1.00 42.52  ? 101 C   B C4    1 
ATOM 4727 N N4    . C   B 2 101 ? 142.123 140.003 149.214 1.00 45.51  ? 101 C   B N4    1 
ATOM 4728 C C5    . C   B 2 101 ? 141.079 138.108 148.212 1.00 36.32  ? 101 C   B C5    1 
ATOM 4729 C C6    . C   B 2 101 ? 141.254 136.952 147.564 1.00 35.27  ? 101 C   B C6    1 
ATOM 4730 P P     . U   B 2 102 ? 141.683 131.625 149.569 1.00 43.54  ? 102 U   B P     1 
ATOM 4731 O OP1   . U   B 2 102 ? 141.689 130.146 149.663 1.00 42.67  ? 102 U   B OP1   1 
ATOM 4732 O OP2   . U   B 2 102 ? 140.563 132.402 150.151 1.00 46.45  ? 102 U   B OP2   1 
ATOM 4733 O "O5'" . U   B 2 102 ? 143.036 132.163 150.213 1.00 40.78  ? 102 U   B "O5'" 1 
ATOM 4734 C "C5'" . U   B 2 102 ? 144.286 131.606 149.842 1.00 40.15  ? 102 U   B "C5'" 1 
ATOM 4735 C "C4'" . U   B 2 102 ? 145.441 132.460 150.301 1.00 40.68  ? 102 U   B "C4'" 1 
ATOM 4736 O "O4'" . U   B 2 102 ? 145.268 133.827 149.856 1.00 41.54  ? 102 U   B "O4'" 1 
ATOM 4737 C "C3'" . U   B 2 102 ? 145.624 132.592 151.800 1.00 40.00  ? 102 U   B "C3'" 1 
ATOM 4738 O "O3'" . U   B 2 102 ? 146.247 131.460 152.373 1.00 40.79  ? 102 U   B "O3'" 1 
ATOM 4739 C "C2'" . U   B 2 102 ? 146.449 133.865 151.917 1.00 40.85  ? 102 U   B "C2'" 1 
ATOM 4740 O "O2'" . U   B 2 102 ? 147.811 133.604 151.622 1.00 47.07  ? 102 U   B "O2'" 1 
ATOM 4741 C "C1'" . U   B 2 102 ? 145.873 134.707 150.777 1.00 40.71  ? 102 U   B "C1'" 1 
ATOM 4742 N N1    . U   B 2 102 ? 144.871 135.690 151.243 1.00 39.34  ? 102 U   B N1    1 
ATOM 4743 C C2    . U   B 2 102 ? 145.344 136.871 151.772 1.00 44.98  ? 102 U   B C2    1 
ATOM 4744 O O2    . U   B 2 102 ? 146.529 137.122 151.876 1.00 49.57  ? 102 U   B O2    1 
ATOM 4745 N N3    . U   B 2 102 ? 144.384 137.755 152.186 1.00 47.79  ? 102 U   B N3    1 
ATOM 4746 C C4    . U   B 2 102 ? 143.022 137.582 152.121 1.00 46.20  ? 102 U   B C4    1 
ATOM 4747 O O4    . U   B 2 102 ? 142.280 138.471 152.534 1.00 47.87  ? 102 U   B O4    1 
ATOM 4748 C C5    . U   B 2 102 ? 142.609 136.338 151.557 1.00 43.33  ? 102 U   B C5    1 
ATOM 4749 C C6    . U   B 2 102 ? 143.525 135.458 151.145 1.00 40.07  ? 102 U   B C6    1 
ATOM 4750 P P     . G   B 2 103 ? 146.105 131.173 153.944 1.00 45.27  ? 103 G   B P     1 
ATOM 4751 O OP1   . G   B 2 103 ? 146.274 129.714 154.156 1.00 45.35  ? 103 G   B OP1   1 
ATOM 4752 O OP2   . G   B 2 103 ? 144.876 131.849 154.425 1.00 50.66  ? 103 G   B OP2   1 
ATOM 4753 O "O5'" . G   B 2 103 ? 147.357 131.923 154.576 1.00 52.26  ? 103 G   B "O5'" 1 
ATOM 4754 C "C5'" . G   B 2 103 ? 148.669 131.663 154.103 1.00 51.62  ? 103 G   B "C5'" 1 
ATOM 4755 C "C4'" . G   B 2 103 ? 149.693 132.521 154.801 1.00 55.81  ? 103 G   B "C4'" 1 
ATOM 4756 O "O4'" . G   B 2 103 ? 149.615 133.886 154.325 1.00 58.10  ? 103 G   B "O4'" 1 
ATOM 4757 C "C3'" . G   B 2 103 ? 149.542 132.647 156.306 1.00 58.71  ? 103 G   B "C3'" 1 
ATOM 4758 O "O3'" . G   B 2 103 ? 150.065 131.528 156.998 1.00 60.76  ? 103 G   B "O3'" 1 
ATOM 4759 C "C2'" . G   B 2 103 ? 150.283 133.942 156.608 1.00 60.48  ? 103 G   B "C2'" 1 
ATOM 4760 O "O2'" . G   B 2 103 ? 151.682 133.715 156.664 1.00 64.96  ? 103 G   B "O2'" 1 
ATOM 4761 C "C1'" . G   B 2 103 ? 149.981 134.774 155.359 1.00 60.65  ? 103 G   B "C1'" 1 
ATOM 4762 N N9    . G   B 2 103 ? 148.894 135.750 155.561 1.00 60.02  ? 103 G   B N9    1 
ATOM 4763 C C8    . G   B 2 103 ? 147.721 135.809 154.856 1.00 57.47  ? 103 G   B C8    1 
ATOM 4764 N N7    . G   B 2 103 ? 146.943 136.785 155.231 1.00 59.24  ? 103 G   B N7    1 
ATOM 4765 C C5    . G   B 2 103 ? 147.646 137.413 156.245 1.00 64.48  ? 103 G   B C5    1 
ATOM 4766 C C6    . G   B 2 103 ? 147.305 138.545 157.028 1.00 69.29  ? 103 G   B C6    1 
ATOM 4767 O O6    . G   B 2 103 ? 146.278 139.227 156.993 1.00 70.48  ? 103 G   B O6    1 
ATOM 4768 N N1    . G   B 2 103 ? 148.298 138.865 157.943 1.00 74.40  ? 103 G   B N1    1 
ATOM 4769 C C2    . G   B 2 103 ? 149.475 138.179 158.082 1.00 76.78  ? 103 G   B C2    1 
ATOM 4770 N N2    . G   B 2 103 ? 150.314 138.634 159.023 1.00 79.97  ? 103 G   B N2    1 
ATOM 4771 N N3    . G   B 2 103 ? 149.810 137.129 157.353 1.00 72.43  ? 103 G   B N3    1 
ATOM 4772 C C4    . G   B 2 103 ? 148.859 136.799 156.453 1.00 65.97  ? 103 G   B C4    1 
ATOM 4773 P P     . A   B 2 104 ? 149.335 130.979 158.317 1.00 63.63  ? 104 A   B P     1 
ATOM 4774 O OP1   . A   B 2 104 ? 149.977 129.696 158.694 1.00 63.26  ? 104 A   B OP1   1 
ATOM 4775 O OP2   . A   B 2 104 ? 147.870 131.030 158.093 1.00 61.09  ? 104 A   B OP2   1 
ATOM 4776 O "O5'" . A   B 2 104 ? 149.693 132.061 159.428 1.00 70.81  ? 104 A   B "O5'" 1 
ATOM 4777 C "C5'" . A   B 2 104 ? 151.031 132.247 159.866 1.00 72.70  ? 104 A   B "C5'" 1 
ATOM 4778 C "C4'" . A   B 2 104 ? 151.111 133.321 160.922 1.00 75.56  ? 104 A   B "C4'" 1 
ATOM 4779 O "O4'" . A   B 2 104 ? 150.904 134.620 160.313 1.00 75.33  ? 104 A   B "O4'" 1 
ATOM 4780 C "C3'" . A   B 2 104 ? 150.056 133.245 162.013 1.00 81.49  ? 104 A   B "C3'" 1 
ATOM 4781 O "O3'" . A   B 2 104 ? 150.406 132.341 163.045 1.00 89.19  ? 104 A   B "O3'" 1 
ATOM 4782 C "C2'" . A   B 2 104 ? 149.947 134.688 162.482 1.00 79.92  ? 104 A   B "C2'" 1 
ATOM 4783 O "O2'" . A   B 2 104 ? 151.012 135.010 163.362 1.00 82.99  ? 104 A   B "O2'" 1 
ATOM 4784 C "C1'" . A   B 2 104 ? 150.157 135.448 161.177 1.00 74.27  ? 104 A   B "C1'" 1 
ATOM 4785 N N9    . A   B 2 104 ? 148.897 135.792 160.495 1.00 73.10  ? 104 A   B N9    1 
ATOM 4786 C C8    . A   B 2 104 ? 148.405 135.159 159.384 1.00 72.45  ? 104 A   B C8    1 
ATOM 4787 N N7    . A   B 2 104 ? 147.284 135.658 158.937 1.00 74.54  ? 104 A   B N7    1 
ATOM 4788 C C5    . A   B 2 104 ? 147.019 136.696 159.812 1.00 74.86  ? 104 A   B C5    1 
ATOM 4789 C C6    . A   B 2 104 ? 145.965 137.617 159.865 1.00 74.11  ? 104 A   B C6    1 
ATOM 4790 N N6    . A   B 2 104 ? 144.962 137.616 158.990 1.00 74.27  ? 104 A   B N6    1 
ATOM 4791 N N1    . A   B 2 104 ? 145.974 138.541 160.846 1.00 75.91  ? 104 A   B N1    1 
ATOM 4792 C C2    . A   B 2 104 ? 146.990 138.533 161.722 1.00 79.39  ? 104 A   B C2    1 
ATOM 4793 N N3    . A   B 2 104 ? 148.043 137.711 161.771 1.00 79.37  ? 104 A   B N3    1 
ATOM 4794 C C4    . A   B 2 104 ? 148.004 136.804 160.775 1.00 75.72  ? 104 A   B C4    1 
ATOM 4795 P P     . G   B 2 105 ? 149.267 131.521 163.822 1.00 98.05  ? 105 G   B P     1 
ATOM 4796 O OP1   . G   B 2 105 ? 149.929 130.447 164.604 1.00 100.62 ? 105 G   B OP1   1 
ATOM 4797 O OP2   . G   B 2 105 ? 148.206 131.169 162.846 1.00 92.08  ? 105 G   B OP2   1 
ATOM 4798 O "O5'" . G   B 2 105 ? 148.660 132.582 164.842 1.00 87.01  ? 105 G   B "O5'" 1 
ATOM 4799 C "C5'" . G   B 2 105 ? 149.479 133.215 165.812 1.00 88.23  ? 105 G   B "C5'" 1 
ATOM 4800 C "C4'" . G   B 2 105 ? 148.758 134.364 166.467 1.00 88.40  ? 105 G   B "C4'" 1 
ATOM 4801 O "O4'" . G   B 2 105 ? 148.535 135.420 165.500 1.00 85.00  ? 105 G   B "O4'" 1 
ATOM 4802 C "C3'" . G   B 2 105 ? 147.372 134.045 166.999 1.00 91.47  ? 105 G   B "C3'" 1 
ATOM 4803 O "O3'" . G   B 2 105 ? 147.416 133.456 168.285 1.00 92.57  ? 105 G   B "O3'" 1 
ATOM 4804 C "C2'" . G   B 2 105 ? 146.674 135.399 166.976 1.00 89.98  ? 105 G   B "C2'" 1 
ATOM 4805 O "O2'" . G   B 2 105 ? 147.037 136.168 168.112 1.00 92.60  ? 105 G   B "O2'" 1 
ATOM 4806 C "C1'" . G   B 2 105 ? 147.294 136.046 165.741 1.00 83.35  ? 105 G   B "C1'" 1 
ATOM 4807 N N9    . G   B 2 105 ? 146.463 135.903 164.531 1.00 83.31  ? 105 G   B N9    1 
ATOM 4808 C C8    . G   B 2 105 ? 146.682 134.995 163.529 1.00 85.00  ? 105 G   B C8    1 
ATOM 4809 N N7    . G   B 2 105 ? 145.834 135.084 162.548 1.00 83.58  ? 105 G   B N7    1 
ATOM 4810 C C5    . G   B 2 105 ? 145.001 136.122 162.926 1.00 83.43  ? 105 G   B C5    1 
ATOM 4811 C C6    . G   B 2 105 ? 143.887 136.664 162.249 1.00 84.15  ? 105 G   B C6    1 
ATOM 4812 O O6    . G   B 2 105 ? 143.435 136.321 161.154 1.00 86.28  ? 105 G   B O6    1 
ATOM 4813 N N1    . G   B 2 105 ? 143.313 137.710 162.957 1.00 81.42  ? 105 G   B N1    1 
ATOM 4814 C C2    . G   B 2 105 ? 143.755 138.167 164.169 1.00 81.90  ? 105 G   B C2    1 
ATOM 4815 N N2    . G   B 2 105 ? 143.048 139.182 164.683 1.00 80.59  ? 105 G   B N2    1 
ATOM 4816 N N3    . G   B 2 105 ? 144.797 137.666 164.820 1.00 84.32  ? 105 G   B N3    1 
ATOM 4817 C C4    . G   B 2 105 ? 145.373 136.650 164.143 1.00 83.90  ? 105 G   B C4    1 
ATOM 4818 P P     . C   B 2 106 ? 146.357 132.323 168.695 1.00 101.14 ? 106 C   B P     1 
ATOM 4819 O OP1   . C   B 2 106 ? 146.725 131.835 170.048 1.00 105.08 ? 106 C   B OP1   1 
ATOM 4820 O OP2   . C   B 2 106 ? 146.246 131.361 167.570 1.00 93.20  ? 106 C   B OP2   1 
ATOM 4821 O "O5'" . C   B 2 106 ? 144.981 133.114 168.813 1.00 96.44  ? 106 C   B "O5'" 1 
ATOM 4822 C "C5'" . C   B 2 106 ? 144.801 134.118 169.799 1.00 95.92  ? 106 C   B "C5'" 1 
ATOM 4823 C "C4'" . C   B 2 106 ? 143.517 134.874 169.577 1.00 93.54  ? 106 C   B "C4'" 1 
ATOM 4824 O "O4'" . C   B 2 106 ? 143.544 135.528 168.285 1.00 85.85  ? 106 C   B "O4'" 1 
ATOM 4825 C "C3'" . C   B 2 106 ? 142.260 134.025 169.534 1.00 98.55  ? 106 C   B "C3'" 1 
ATOM 4826 O "O3'" . C   B 2 106 ? 141.789 133.697 170.827 1.00 102.90 ? 106 C   B "O3'" 1 
ATOM 4827 C "C2'" . C   B 2 106 ? 141.296 134.884 168.724 1.00 97.17  ? 106 C   B "C2'" 1 
ATOM 4828 O "O2'" . C   B 2 106 ? 140.714 135.887 169.542 1.00 96.45  ? 106 C   B "O2'" 1 
ATOM 4829 C "C1'" . C   B 2 106 ? 142.242 135.569 167.737 1.00 88.39  ? 106 C   B "C1'" 1 
ATOM 4830 N N1    . C   B 2 106 ? 142.268 134.948 166.388 1.00 88.68  ? 106 C   B N1    1 
ATOM 4831 C C2    . C   B 2 106 ? 141.500 135.510 165.362 1.00 85.34  ? 106 C   B C2    1 
ATOM 4832 O O2    . C   B 2 106 ? 140.760 136.478 165.577 1.00 84.92  ? 106 C   B O2    1 
ATOM 4833 N N3    . C   B 2 106 ? 141.523 134.969 164.123 1.00 85.06  ? 106 C   B N3    1 
ATOM 4834 C C4    . C   B 2 106 ? 142.309 133.921 163.876 1.00 85.38  ? 106 C   B C4    1 
ATOM 4835 N N4    . C   B 2 106 ? 142.311 133.423 162.640 1.00 88.48  ? 106 C   B N4    1 
ATOM 4836 C C5    . C   B 2 106 ? 143.117 133.329 164.886 1.00 88.80  ? 106 C   B C5    1 
ATOM 4837 C C6    . C   B 2 106 ? 143.069 133.873 166.107 1.00 91.83  ? 106 C   B C6    1 
ATOM 4838 P P     . C   B 2 107 ? 141.025 132.309 171.080 1.00 110.78 ? 107 C   B P     1 
ATOM 4839 O OP1   . C   B 2 107 ? 141.418 131.806 172.422 1.00 111.99 ? 107 C   B OP1   1 
ATOM 4840 O OP2   . C   B 2 107 ? 141.217 131.446 169.887 1.00 107.81 ? 107 C   B OP2   1 
ATOM 4841 O "O5'" . C   B 2 107 ? 139.497 132.744 171.141 1.00 110.19 ? 107 C   B "O5'" 1 
ATOM 4842 C "C5'" . C   B 2 107 ? 139.136 134.011 171.679 1.00 108.64 ? 107 C   B "C5'" 1 
ATOM 4843 C "C4'" . C   B 2 107 ? 137.925 134.599 170.996 1.00 110.04 ? 107 C   B "C4'" 1 
ATOM 4844 O "O4'" . C   B 2 107 ? 138.110 134.580 169.552 1.00 105.57 ? 107 C   B "O4'" 1 
ATOM 4845 C "C3'" . C   B 2 107 ? 136.603 133.879 171.265 1.00 117.68 ? 107 C   B "C3'" 1 
ATOM 4846 O "O3'" . C   B 2 107 ? 135.550 134.838 171.313 1.00 120.45 ? 107 C   B "O3'" 1 
ATOM 4847 C "C2'" . C   B 2 107 ? 136.430 133.022 170.015 1.00 114.22 ? 107 C   B "C2'" 1 
ATOM 4848 O "O2'" . C   B 2 107 ? 135.097 132.653 169.735 1.00 118.41 ? 107 C   B "O2'" 1 
ATOM 4849 C "C1'" . C   B 2 107 ? 137.003 133.945 168.946 1.00 105.36 ? 107 C   B "C1'" 1 
ATOM 4850 N N1    . C   B 2 107 ? 137.451 133.256 167.726 1.00 101.97 ? 107 C   B N1    1 
ATOM 4851 C C2    . C   B 2 107 ? 136.966 133.719 166.503 1.00 93.81  ? 107 C   B C2    1 
ATOM 4852 O O2    . C   B 2 107 ? 136.196 134.688 166.499 1.00 89.62  ? 107 C   B O2    1 
ATOM 4853 N N3    . C   B 2 107 ? 137.349 133.106 165.361 1.00 92.42  ? 107 C   B N3    1 
ATOM 4854 C C4    . C   B 2 107 ? 138.182 132.066 165.416 1.00 94.91  ? 107 C   B C4    1 
ATOM 4855 N N4    . C   B 2 107 ? 138.536 131.488 164.266 1.00 96.87  ? 107 C   B N4    1 
ATOM 4856 C C5    . C   B 2 107 ? 138.689 131.568 166.651 1.00 98.11  ? 107 C   B C5    1 
ATOM 4857 C C6    . C   B 2 107 ? 138.299 132.186 167.773 1.00 102.77 ? 107 C   B C6    1 
ATOM 4858 P P     . U   B 2 108 ? 135.206 135.613 172.677 1.00 127.16 ? 108 U   B P     1 
ATOM 4859 O OP1   . U   B 2 108 ? 136.268 135.355 173.682 1.00 127.37 ? 108 U   B OP1   1 
ATOM 4860 O OP2   . U   B 2 108 ? 133.795 135.305 173.018 1.00 118.93 ? 108 U   B OP2   1 
ATOM 4861 O "O5'" . U   B 2 108 ? 135.282 137.147 172.259 1.00 114.14 ? 108 U   B "O5'" 1 
ATOM 4862 C "C5'" . U   B 2 108 ? 134.573 138.137 172.986 1.00 109.61 ? 108 U   B "C5'" 1 
ATOM 4863 C "C4'" . U   B 2 108 ? 134.094 139.239 172.078 1.00 107.05 ? 108 U   B "C4'" 1 
ATOM 4864 O "O4'" . U   B 2 108 ? 135.229 139.848 171.407 1.00 111.39 ? 108 U   B "O4'" 1 
ATOM 4865 C "C3'" . U   B 2 108 ? 133.188 138.813 170.936 1.00 104.73 ? 108 U   B "C3'" 1 
ATOM 4866 O "O3'" . U   B 2 108 ? 131.844 138.602 171.325 1.00 110.60 ? 108 U   B "O3'" 1 
ATOM 4867 C "C2'" . U   B 2 108 ? 133.368 139.945 169.936 1.00 102.00 ? 108 U   B "C2'" 1 
ATOM 4868 O "O2'" . U   B 2 108 ? 132.624 141.087 170.333 1.00 97.04  ? 108 U   B "O2'" 1 
ATOM 4869 C "C1'" . U   B 2 108 ? 134.855 140.257 170.106 1.00 105.98 ? 108 U   B "C1'" 1 
ATOM 4870 N N1    . U   B 2 108 ? 135.691 139.541 169.111 1.00 104.88 ? 108 U   B N1    1 
ATOM 4871 C C2    . U   B 2 108 ? 135.779 140.083 167.840 1.00 96.29  ? 108 U   B C2    1 
ATOM 4872 O O2    . U   B 2 108 ? 135.214 141.109 167.503 1.00 87.85  ? 108 U   B O2    1 
ATOM 4873 N N3    . U   B 2 108 ? 136.563 139.375 166.966 1.00 97.03  ? 108 U   B N3    1 
ATOM 4874 C C4    . U   B 2 108 ? 137.253 138.209 167.220 1.00 100.93 ? 108 U   B C4    1 
ATOM 4875 O O4    . U   B 2 108 ? 137.918 137.694 166.322 1.00 101.17 ? 108 U   B O4    1 
ATOM 4876 C C5    . U   B 2 108 ? 137.114 137.707 168.551 1.00 101.60 ? 108 U   B C5    1 
ATOM 4877 C C6    . U   B 2 108 ? 136.360 138.377 169.425 1.00 105.74 ? 108 U   B C6    1 
ATOM 4878 P P     . C   B 2 109 ? 130.923 137.581 170.493 1.00 117.26 ? 109 C   B P     1 
ATOM 4879 O OP1   . C   B 2 109 ? 129.688 137.338 171.280 1.00 115.79 ? 109 C   B OP1   1 
ATOM 4880 O OP2   . C   B 2 109 ? 131.769 136.431 170.084 1.00 116.03 ? 109 C   B OP2   1 
ATOM 4881 O "O5'" . C   B 2 109 ? 130.522 138.396 169.184 1.00 99.26  ? 109 C   B "O5'" 1 
ATOM 4882 C "C5'" . C   B 2 109 ? 129.724 139.566 169.276 1.00 97.53  ? 109 C   B "C5'" 1 
ATOM 4883 C "C4'" . C   B 2 109 ? 129.631 140.298 167.960 1.00 100.04 ? 109 C   B "C4'" 1 
ATOM 4884 O "O4'" . C   B 2 109 ? 130.958 140.628 167.466 1.00 104.26 ? 109 C   B "O4'" 1 
ATOM 4885 C "C3'" . C   B 2 109 ? 129.004 139.539 166.803 1.00 101.16 ? 109 C   B "C3'" 1 
ATOM 4886 O "O3'" . C   B 2 109 ? 127.592 139.474 166.859 1.00 108.70 ? 109 C   B "O3'" 1 
ATOM 4887 C "C2'" . C   B 2 109 ? 129.528 140.303 165.598 1.00 93.19  ? 109 C   B "C2'" 1 
ATOM 4888 O "O2'" . C   B 2 109 ? 128.822 141.524 165.436 1.00 87.02  ? 109 C   B "O2'" 1 
ATOM 4889 C "C1'" . C   B 2 109 ? 130.953 140.626 166.048 1.00 95.34  ? 109 C   B "C1'" 1 
ATOM 4890 N N1    . C   B 2 109 ? 131.933 139.627 165.552 1.00 88.41  ? 109 C   B N1    1 
ATOM 4891 C C2    . C   B 2 109 ? 132.314 139.625 164.202 1.00 76.14  ? 109 C   B C2    1 
ATOM 4892 O O2    . C   B 2 109 ? 131.841 140.458 163.418 1.00 74.46  ? 109 C   B O2    1 
ATOM 4893 N N3    . C   B 2 109 ? 133.204 138.710 163.764 1.00 73.82  ? 109 C   B N3    1 
ATOM 4894 C C4    . C   B 2 109 ? 133.720 137.815 164.601 1.00 79.41  ? 109 C   B C4    1 
ATOM 4895 N N4    . C   B 2 109 ? 134.596 136.933 164.118 1.00 78.55  ? 109 C   B N4    1 
ATOM 4896 C C5    . C   B 2 109 ? 133.359 137.786 165.974 1.00 92.17  ? 109 C   B C5    1 
ATOM 4897 C C6    . C   B 2 109 ? 132.476 138.698 166.396 1.00 96.98  ? 109 C   B C6    1 
ATOM 4898 P P     . U   B 2 110 ? 126.838 138.121 166.424 1.00 116.49 ? 110 U   B P     1 
ATOM 4899 O OP1   . U   B 2 110 ? 125.382 138.386 166.479 1.00 113.08 ? 110 U   B OP1   1 
ATOM 4900 O OP2   . U   B 2 110 ? 127.408 137.004 167.221 1.00 114.33 ? 110 U   B OP2   1 
ATOM 4901 O "O5'" . U   B 2 110 ? 127.255 137.898 164.900 1.00 92.71  ? 110 U   B "O5'" 1 
ATOM 4902 C "C5'" . U   B 2 110 ? 126.729 138.713 163.861 1.00 89.20  ? 110 U   B "C5'" 1 
ATOM 4903 C "C4'" . U   B 2 110 ? 127.487 138.527 162.566 1.00 87.81  ? 110 U   B "C4'" 1 
ATOM 4904 O "O4'" . U   B 2 110 ? 128.916 138.529 162.826 1.00 87.29  ? 110 U   B "O4'" 1 
ATOM 4905 C "C3'" . U   B 2 110 ? 127.252 137.217 161.827 1.00 89.56  ? 110 U   B "C3'" 1 
ATOM 4906 O "O3'" . U   B 2 110 ? 126.067 137.219 161.049 1.00 93.09  ? 110 U   B "O3'" 1 
ATOM 4907 C "C2'" . U   B 2 110 ? 128.516 137.075 160.991 1.00 75.05  ? 110 U   B "C2'" 1 
ATOM 4908 O "O2'" . U   B 2 110 ? 128.447 137.903 159.841 1.00 63.79  ? 110 U   B "O2'" 1 
ATOM 4909 C "C1'" . U   B 2 110 ? 129.572 137.654 161.931 1.00 78.63  ? 110 U   B "C1'" 1 
ATOM 4910 N N1    . U   B 2 110 ? 130.281 136.614 162.717 1.00 78.22  ? 110 U   B N1    1 
ATOM 4911 C C2    . U   B 2 110 ? 131.191 135.780 162.087 1.00 76.13  ? 110 U   B C2    1 
ATOM 4912 O O2    . U   B 2 110 ? 131.454 135.826 160.900 1.00 78.02  ? 110 U   B O2    1 
ATOM 4913 N N3    . U   B 2 110 ? 131.801 134.862 162.902 1.00 79.79  ? 110 U   B N3    1 
ATOM 4914 C C4    . U   B 2 110 ? 131.615 134.692 164.255 1.00 88.87  ? 110 U   B C4    1 
ATOM 4915 O O4    . U   B 2 110 ? 132.242 133.813 164.848 1.00 96.26  ? 110 U   B O4    1 
ATOM 4916 C C5    . U   B 2 110 ? 130.668 135.589 164.835 1.00 88.14  ? 110 U   B C5    1 
ATOM 4917 C C6    . U   B 2 110 ? 130.058 136.495 164.067 1.00 85.16  ? 110 U   B C6    1 
ATOM 4918 P P     . A   B 2 111 ? 125.184 135.883 160.910 1.00 104.01 ? 111 A   B P     1 
ATOM 4919 O OP1   . A   B 2 111 ? 124.070 136.190 159.981 1.00 86.39  ? 111 A   B OP1   1 
ATOM 4920 O OP2   . A   B 2 111 ? 124.892 135.363 162.270 1.00 99.38  ? 111 A   B OP2   1 
ATOM 4921 O "O5'" . A   B 2 111 ? 126.148 134.840 160.188 1.00 87.17  ? 111 A   B "O5'" 1 
ATOM 4922 C "C5'" . A   B 2 111 ? 126.014 134.565 158.802 1.00 74.60  ? 111 A   B "C5'" 1 
ATOM 4923 C "C4'" . A   B 2 111 ? 127.005 133.528 158.339 1.00 76.03  ? 111 A   B "C4'" 1 
ATOM 4924 O "O4'" . A   B 2 111 ? 128.294 133.776 158.946 1.00 77.16  ? 111 A   B "O4'" 1 
ATOM 4925 C "C3'" . A   B 2 111 ? 126.703 132.085 158.708 1.00 86.90  ? 111 A   B "C3'" 1 
ATOM 4926 O "O3'" . A   B 2 111 ? 125.763 131.482 157.834 1.00 86.51  ? 111 A   B "O3'" 1 
ATOM 4927 C "C2'" . A   B 2 111 ? 128.077 131.427 158.647 1.00 89.20  ? 111 A   B "C2'" 1 
ATOM 4928 O "O2'" . A   B 2 111 ? 128.414 131.097 157.308 1.00 82.13  ? 111 A   B "O2'" 1 
ATOM 4929 C "C1'" . A   B 2 111 ? 128.991 132.559 159.103 1.00 82.87  ? 111 A   B "C1'" 1 
ATOM 4930 N N9    . A   B 2 111 ? 129.453 132.427 160.498 1.00 83.63  ? 111 A   B N9    1 
ATOM 4931 C C8    . A   B 2 111 ? 129.017 133.095 161.612 1.00 80.27  ? 111 A   B C8    1 
ATOM 4932 N N7    . A   B 2 111 ? 129.663 132.769 162.704 1.00 83.44  ? 111 A   B N7    1 
ATOM 4933 C C5    . A   B 2 111 ? 130.595 131.836 162.279 1.00 85.43  ? 111 A   B C5    1 
ATOM 4934 C C6    . A   B 2 111 ? 131.588 131.104 162.952 1.00 91.58  ? 111 A   B C6    1 
ATOM 4935 N N6    . A   B 2 111 ? 131.815 131.205 164.261 1.00 94.51  ? 111 A   B N6    1 
ATOM 4936 N N1    . A   B 2 111 ? 132.352 130.251 162.230 1.00 93.53  ? 111 A   B N1    1 
ATOM 4937 C C2    . A   B 2 111 ? 132.123 130.149 160.915 1.00 95.80  ? 111 A   B C2    1 
ATOM 4938 N N3    . A   B 2 111 ? 131.219 130.785 160.173 1.00 95.04  ? 111 A   B N3    1 
ATOM 4939 C C4    . A   B 2 111 ? 130.480 131.621 160.921 1.00 87.20  ? 111 A   B C4    1 
ATOM 4940 P P     . U   B 2 112 ? 124.790 130.311 158.354 1.00 90.81  ? 112 U   B P     1 
ATOM 4941 O OP1   . U   B 2 112 ? 124.025 129.829 157.178 1.00 79.36  ? 112 U   B OP1   1 
ATOM 4942 O OP2   . U   B 2 112 ? 124.066 130.804 159.553 1.00 91.02  ? 112 U   B OP2   1 
ATOM 4943 O "O5'" . U   B 2 112 ? 125.771 129.131 158.790 1.00 96.86  ? 112 U   B "O5'" 1 
ATOM 4944 C "C5'" . U   B 2 112 ? 126.384 128.307 157.811 1.00 97.01  ? 112 U   B "C5'" 1 
ATOM 4945 C "C4'" . U   B 2 112 ? 127.482 127.441 158.383 1.00 105.13 ? 112 U   B "C4'" 1 
ATOM 4946 O "O4'" . U   B 2 112 ? 128.348 128.196 159.261 1.00 103.80 ? 112 U   B "O4'" 1 
ATOM 4947 C "C3'" . U   B 2 112 ? 127.059 126.259 159.234 1.00 114.55 ? 112 U   B "C3'" 1 
ATOM 4948 O "O3'" . U   B 2 112 ? 126.609 125.172 158.446 1.00 125.23 ? 112 U   B "O3'" 1 
ATOM 4949 C "C2'" . U   B 2 112 ? 128.331 125.933 160.021 1.00 112.42 ? 112 U   B "C2'" 1 
ATOM 4950 O "O2'" . U   B 2 112 ? 129.175 125.068 159.276 1.00 118.35 ? 112 U   B "O2'" 1 
ATOM 4951 C "C1'" . U   B 2 112 ? 129.016 127.304 160.126 1.00 103.38 ? 112 U   B "C1'" 1 
ATOM 4952 N N1    . U   B 2 112 ? 129.079 127.838 161.509 1.00 97.70  ? 112 U   B N1    1 
ATOM 4953 C C2    . U   B 2 112 ? 130.153 127.387 162.261 1.00 102.19 ? 112 U   B C2    1 
ATOM 4954 O O2    . U   B 2 112 ? 130.981 126.605 161.828 1.00 102.54 ? 112 U   B O2    1 
ATOM 4955 N N3    . U   B 2 112 ? 130.244 127.870 163.540 1.00 103.72 ? 112 U   B N3    1 
ATOM 4956 C C4    . U   B 2 112 ? 129.370 128.756 164.133 1.00 102.10 ? 112 U   B C4    1 
ATOM 4957 O O4    . U   B 2 112 ? 129.571 129.109 165.297 1.00 99.99  ? 112 U   B O4    1 
ATOM 4958 C C5    . U   B 2 112 ? 128.286 129.181 163.292 1.00 97.75  ? 112 U   B C5    1 
ATOM 4959 C C6    . U   B 2 112 ? 128.174 128.725 162.037 1.00 92.84  ? 112 U   B C6    1 
ATOM 4960 P P     . G   B 2 113 ? 125.097 124.646 158.561 1.00 129.67 ? 113 G   B P     1 
ATOM 4961 O OP1   . G   B 2 113 ? 124.200 125.821 158.699 1.00 124.17 ? 113 G   B OP1   1 
ATOM 4962 O OP2   . G   B 2 113 ? 125.066 123.563 159.576 1.00 126.34 ? 113 G   B OP2   1 
ATOM 4963 O "O5'" . G   B 2 113 ? 124.821 123.987 157.139 1.00 134.39 ? 113 G   B "O5'" 1 
ATOM 4964 C "C5'" . G   B 2 113 ? 125.035 124.721 155.944 1.00 133.97 ? 113 G   B "C5'" 1 
ATOM 4965 C "C4'" . G   B 2 113 ? 125.656 123.859 154.875 1.00 140.66 ? 113 G   B "C4'" 1 
ATOM 4966 O "O4'" . G   B 2 113 ? 127.078 123.713 155.118 1.00 139.62 ? 113 G   B "O4'" 1 
ATOM 4967 C "C3'" . G   B 2 113 ? 125.146 122.430 154.802 1.00 149.85 ? 113 G   B "C3'" 1 
ATOM 4968 O "O3'" . G   B 2 113 ? 123.919 122.319 154.104 1.00 159.15 ? 113 G   B "O3'" 1 
ATOM 4969 C "C2'" . G   B 2 113 ? 126.297 121.698 154.129 1.00 149.83 ? 113 G   B "C2'" 1 
ATOM 4970 O "O2'" . G   B 2 113 ? 126.274 121.914 152.726 1.00 148.40 ? 113 G   B "O2'" 1 
ATOM 4971 C "C1'" . G   B 2 113 ? 127.508 122.433 154.706 1.00 145.80 ? 113 G   B "C1'" 1 
ATOM 4972 N N9    . G   B 2 113 ? 128.114 121.739 155.861 1.00 149.52 ? 113 G   B N9    1 
ATOM 4973 C C8    . G   B 2 113 ? 128.276 122.253 157.125 1.00 147.63 ? 113 G   B C8    1 
ATOM 4974 N N7    . G   B 2 113 ? 128.862 121.426 157.948 1.00 151.23 ? 113 G   B N7    1 
ATOM 4975 C C5    . G   B 2 113 ? 129.118 120.296 157.183 1.00 158.36 ? 113 G   B C5    1 
ATOM 4976 C C6    . G   B 2 113 ? 129.736 119.063 157.531 1.00 162.60 ? 113 G   B C6    1 
ATOM 4977 O O6    . G   B 2 113 ? 130.201 118.718 158.624 1.00 164.13 ? 113 G   B O6    1 
ATOM 4978 N N1    . G   B 2 113 ? 129.793 118.184 156.452 1.00 163.99 ? 113 G   B N1    1 
ATOM 4979 C C2    . G   B 2 113 ? 129.311 118.468 155.201 1.00 162.42 ? 113 G   B C2    1 
ATOM 4980 N N2    . G   B 2 113 ? 129.440 117.513 154.274 1.00 164.72 ? 113 G   B N2    1 
ATOM 4981 N N3    . G   B 2 113 ? 128.736 119.606 154.865 1.00 158.43 ? 113 G   B N3    1 
ATOM 4982 C C4    . G   B 2 113 ? 128.667 120.476 155.892 1.00 156.85 ? 113 G   B C4    1 
ATOM 4983 P P     . C   B 2 114 ? 122.815 121.254 154.579 1.00 165.11 ? 114 C   B P     1 
ATOM 4984 O OP1   . C   B 2 114 ? 121.616 121.439 153.724 1.00 159.82 ? 114 C   B OP1   1 
ATOM 4985 O OP2   . C   B 2 114 ? 122.684 121.346 156.055 1.00 156.14 ? 114 C   B OP2   1 
ATOM 4986 O "O5'" . C   B 2 114 ? 123.463 119.844 154.219 1.00 168.69 ? 114 C   B "O5'" 1 
ATOM 4987 C "C5'" . C   B 2 114 ? 123.617 119.441 152.867 1.00 166.31 ? 114 C   B "C5'" 1 
ATOM 4988 C "C4'" . C   B 2 114 ? 124.241 118.072 152.757 1.00 166.64 ? 114 C   B "C4'" 1 
ATOM 4989 O "O4'" . C   B 2 114 ? 125.572 118.080 153.331 1.00 163.99 ? 114 C   B "O4'" 1 
ATOM 4990 C "C3'" . C   B 2 114 ? 123.533 116.948 153.494 1.00 173.07 ? 114 C   B "C3'" 1 
ATOM 4991 O "O3'" . C   B 2 114 ? 122.410 116.453 152.786 1.00 176.01 ? 114 C   B "O3'" 1 
ATOM 4992 C "C2'" . C   B 2 114 ? 124.640 115.915 153.665 1.00 173.07 ? 114 C   B "C2'" 1 
ATOM 4993 O "O2'" . C   B 2 114 ? 124.807 115.160 152.474 1.00 174.39 ? 114 C   B "O2'" 1 
ATOM 4994 C "C1'" . C   B 2 114 ? 125.874 116.802 153.850 1.00 166.99 ? 114 C   B "C1'" 1 
ATOM 4995 N N1    . C   B 2 114 ? 126.293 116.927 155.267 1.00 167.92 ? 114 C   B N1    1 
ATOM 4996 C C2    . C   B 2 114 ? 127.009 115.872 155.852 1.00 172.68 ? 114 C   B C2    1 
ATOM 4997 O O2    . C   B 2 114 ? 127.262 114.866 155.171 1.00 172.40 ? 114 C   B O2    1 
ATOM 4998 N N3    . C   B 2 114 ? 127.410 115.967 157.140 1.00 175.79 ? 114 C   B N3    1 
ATOM 4999 C C4    . C   B 2 114 ? 127.125 117.064 157.841 1.00 173.98 ? 114 C   B C4    1 
ATOM 5000 N N4    . C   B 2 114 ? 127.543 117.116 159.108 1.00 173.42 ? 114 C   B N4    1 
ATOM 5001 C C5    . C   B 2 114 ? 126.406 118.157 157.273 1.00 169.26 ? 114 C   B C5    1 
ATOM 5002 C C6    . C   B 2 114 ? 126.013 118.049 155.996 1.00 166.62 ? 114 C   B C6    1 
ATOM 5003 P P     . C   B 2 115 ? 121.170 115.796 153.571 1.00 180.32 ? 115 C   B P     1 
ATOM 5004 O OP1   . C   B 2 115 ? 120.136 115.467 152.558 1.00 177.06 ? 115 C   B OP1   1 
ATOM 5005 O OP2   . C   B 2 115 ? 120.819 116.664 154.723 1.00 179.51 ? 115 C   B OP2   1 
ATOM 5006 O "O5'" . C   B 2 115 ? 121.749 114.423 154.139 1.00 182.58 ? 115 C   B "O5'" 1 
ATOM 5007 C "C5'" . C   B 2 115 ? 122.038 113.343 153.264 1.00 181.30 ? 115 C   B "C5'" 1 
ATOM 5008 C "C4'" . C   B 2 115 ? 122.634 112.167 153.996 1.00 183.43 ? 115 C   B "C4'" 1 
ATOM 5009 O "O4'" . C   B 2 115 ? 123.887 112.540 154.627 1.00 183.14 ? 115 C   B "O4'" 1 
ATOM 5010 C "C3'" . C   B 2 115 ? 121.819 111.596 155.142 1.00 188.40 ? 115 C   B "C3'" 1 
ATOM 5011 O "O3'" . C   B 2 115 ? 120.728 110.800 154.721 1.00 188.96 ? 115 C   B "O3'" 1 
ATOM 5012 C "C2'" . C   B 2 115 ? 122.871 110.830 155.934 1.00 189.89 ? 115 C   B "C2'" 1 
ATOM 5013 O "O2'" . C   B 2 115 ? 123.158 109.585 155.315 1.00 190.92 ? 115 C   B "O2'" 1 
ATOM 5014 C "C1'" . C   B 2 115 ? 124.092 111.742 155.778 1.00 186.26 ? 115 C   B "C1'" 1 
ATOM 5015 N N1    . C   B 2 115 ? 124.292 112.606 156.965 1.00 184.51 ? 115 C   B N1    1 
ATOM 5016 C C2    . C   B 2 115 ? 125.027 112.074 158.031 1.00 186.88 ? 115 C   B C2    1 
ATOM 5017 O O2    . C   B 2 115 ? 125.486 110.926 157.921 1.00 187.57 ? 115 C   B O2    1 
ATOM 5018 N N3    . C   B 2 115 ? 125.230 112.817 159.143 1.00 188.09 ? 115 C   B N3    1 
ATOM 5019 C C4    . C   B 2 115 ? 124.720 114.047 159.215 1.00 187.16 ? 115 C   B C4    1 
ATOM 5020 N N4    . C   B 2 115 ? 124.940 114.751 160.326 1.00 188.81 ? 115 C   B N4    1 
ATOM 5021 C C5    . C   B 2 115 ? 123.961 114.615 158.150 1.00 183.56 ? 115 C   B C5    1 
ATOM 5022 C C6    . C   B 2 115 ? 123.771 113.868 157.055 1.00 182.63 ? 115 C   B C6    1 
ATOM 5023 P P     . A   B 2 116 ? 119.405 110.723 155.629 1.00 191.51 ? 116 A   B P     1 
ATOM 5024 O OP1   . A   B 2 116 ? 118.322 110.108 154.821 1.00 187.91 ? 116 A   B OP1   1 
ATOM 5025 O OP2   . A   B 2 116 ? 119.197 112.059 156.244 1.00 190.84 ? 116 A   B OP2   1 
ATOM 5026 O "O5'" . A   B 2 116 ? 119.797 109.709 156.792 1.00 195.30 ? 116 A   B "O5'" 1 
ATOM 5027 C "C5'" . A   B 2 116 ? 120.126 108.361 156.497 1.00 196.01 ? 116 A   B "C5'" 1 
ATOM 5028 C "C4'" . A   B 2 116 ? 120.648 107.634 157.709 1.00 198.71 ? 116 A   B "C4'" 1 
ATOM 5029 O "O4'" . A   B 2 116 ? 121.943 108.165 158.095 1.00 197.72 ? 116 A   B "O4'" 1 
ATOM 5030 C "C3'" . A   B 2 116 ? 119.820 107.754 158.977 1.00 201.65 ? 116 A   B "C3'" 1 
ATOM 5031 O "O3'" . A   B 2 116 ? 118.677 106.918 158.989 1.00 202.43 ? 116 A   B "O3'" 1 
ATOM 5032 C "C2'" . A   B 2 116 ? 120.837 107.415 160.056 1.00 203.78 ? 116 A   B "C2'" 1 
ATOM 5033 O "O2'" . A   B 2 116 ? 121.061 106.015 160.113 1.00 206.19 ? 116 A   B "O2'" 1 
ATOM 5034 C "C1'" . A   B 2 116 ? 122.092 108.082 159.499 1.00 200.38 ? 116 A   B "C1'" 1 
ATOM 5035 N N9    . A   B 2 116 ? 122.275 109.441 160.043 1.00 198.73 ? 116 A   B N9    1 
ATOM 5036 C C8    . A   B 2 116 ? 121.997 110.635 159.426 1.00 195.35 ? 116 A   B C8    1 
ATOM 5037 N N7    . A   B 2 116 ? 122.263 111.684 160.163 1.00 196.47 ? 116 A   B N7    1 
ATOM 5038 C C5    . A   B 2 116 ? 122.745 111.145 161.346 1.00 199.85 ? 116 A   B C5    1 
ATOM 5039 C C6    . A   B 2 116 ? 123.197 111.734 162.539 1.00 202.59 ? 116 A   B C6    1 
ATOM 5040 N N6    . A   B 2 116 ? 123.247 113.053 162.727 1.00 202.62 ? 116 A   B N6    1 
ATOM 5041 N N1    . A   B 2 116 ? 123.618 110.924 163.538 1.00 203.91 ? 116 A   B N1    1 
ATOM 5042 C C2    . A   B 2 116 ? 123.576 109.599 163.344 1.00 203.27 ? 116 A   B C2    1 
ATOM 5043 N N3    . A   B 2 116 ? 123.165 108.927 162.266 1.00 201.79 ? 116 A   B N3    1 
ATOM 5044 C C4    . A   B 2 116 ? 122.758 109.765 161.292 1.00 200.35 ? 116 A   B C4    1 
ATOM 5045 P P     . G   B 2 117 ? 117.301 107.456 159.621 1.00 204.55 ? 117 G   B P     1 
ATOM 5046 O OP1   . G   B 2 117 ? 116.282 106.387 159.469 1.00 208.45 ? 117 G   B OP1   1 
ATOM 5047 O OP2   . G   B 2 117 ? 117.039 108.809 159.066 1.00 199.50 ? 117 G   B OP2   1 
ATOM 5048 O "O5'" . G   B 2 117 ? 117.622 107.616 161.174 1.00 208.30 ? 117 G   B "O5'" 1 
ATOM 5049 C "C5'" . G   B 2 117 ? 117.760 106.476 162.009 1.00 211.53 ? 117 G   B "C5'" 1 
ATOM 5050 C "C4'" . G   B 2 117 ? 118.462 106.809 163.303 1.00 214.46 ? 117 G   B "C4'" 1 
ATOM 5051 O "O4'" . G   B 2 117 ? 119.647 107.600 163.032 1.00 212.91 ? 117 G   B "O4'" 1 
ATOM 5052 C "C3'" . G   B 2 117 ? 117.681 107.653 164.297 1.00 218.00 ? 117 G   B "C3'" 1 
ATOM 5053 O "O3'" . G   B 2 117 ? 116.753 106.899 165.057 1.00 222.48 ? 117 G   B "O3'" 1 
ATOM 5054 C "C2'" . G   B 2 117 ? 118.785 108.279 165.136 1.00 216.75 ? 117 G   B "C2'" 1 
ATOM 5055 O "O2'" . G   B 2 117 ? 119.286 107.350 166.085 1.00 217.08 ? 117 G   B "O2'" 1 
ATOM 5056 C "C1'" . G   B 2 117 ? 119.864 108.519 164.080 1.00 213.04 ? 117 G   B "C1'" 1 
ATOM 5057 N N9    . G   B 2 117 ? 119.797 109.888 163.537 1.00 211.81 ? 117 G   B N9    1 
ATOM 5058 C C8    . G   B 2 117 ? 119.350 110.304 162.307 1.00 208.43 ? 117 G   B C8    1 
ATOM 5059 N N7    . G   B 2 117 ? 119.422 111.600 162.150 1.00 206.69 ? 117 G   B N7    1 
ATOM 5060 C C5    . G   B 2 117 ? 119.948 112.064 163.349 1.00 211.00 ? 117 G   B C5    1 
ATOM 5061 C C6    . G   B 2 117 ? 120.253 113.381 163.785 1.00 213.99 ? 117 G   B C6    1 
ATOM 5062 O O6    . G   B 2 117 ? 120.126 114.446 163.169 1.00 213.43 ? 117 G   B O6    1 
ATOM 5063 N N1    . G   B 2 117 ? 120.771 113.386 165.078 1.00 217.59 ? 117 G   B N1    1 
ATOM 5064 C C2    . G   B 2 117 ? 120.963 112.270 165.854 1.00 218.26 ? 117 G   B C2    1 
ATOM 5065 N N2    . G   B 2 117 ? 121.468 112.457 167.079 1.00 221.04 ? 117 G   B N2    1 
ATOM 5066 N N3    . G   B 2 117 ? 120.680 111.044 165.462 1.00 215.89 ? 117 G   B N3    1 
ATOM 5067 C C4    . G   B 2 117 ? 120.181 111.018 164.211 1.00 213.29 ? 117 G   B C4    1 
ATOM 5068 P P     . A   B 2 118 ? 115.179 107.193 164.926 1.00 226.23 ? 118 A   B P     1 
ATOM 5069 O OP1   . A   B 2 118 ? 114.462 106.276 165.847 1.00 225.36 ? 118 A   B OP1   1 
ATOM 5070 O OP2   . A   B 2 118 ? 114.832 107.188 163.482 1.00 220.25 ? 118 A   B OP2   1 
ATOM 5071 O "O5'" . A   B 2 118 ? 115.015 108.683 165.466 1.00 227.40 ? 118 A   B "O5'" 1 
ATOM 5072 C "C5'" . A   B 2 118 ? 114.080 109.565 164.864 1.00 227.54 ? 118 A   B "C5'" 1 
ATOM 5073 C "C4'" . A   B 2 118 ? 113.676 110.690 165.786 1.00 230.30 ? 118 A   B "C4'" 1 
ATOM 5074 O "O4'" . A   B 2 118 ? 113.054 110.165 166.984 1.00 231.26 ? 118 A   B "O4'" 1 
ATOM 5075 C "C3'" . A   B 2 118 ? 114.790 111.588 166.308 1.00 232.19 ? 118 A   B "C3'" 1 
ATOM 5076 O "O3'" . A   B 2 118 ? 115.188 112.546 165.333 1.00 233.36 ? 118 A   B "O3'" 1 
ATOM 5077 C "C2'" . A   B 2 118 ? 114.171 112.191 167.569 1.00 232.68 ? 118 A   B "C2'" 1 
ATOM 5078 O "O2'" . A   B 2 118 ? 113.348 113.302 167.246 1.00 234.35 ? 118 A   B "O2'" 1 
ATOM 5079 C "C1'" . A   B 2 118 ? 113.269 111.053 168.059 1.00 232.17 ? 118 A   B "C1'" 1 
ATOM 5080 N N9    . A   B 2 118 ? 113.798 110.328 169.237 1.00 230.76 ? 118 A   B N9    1 
ATOM 5081 C C8    . A   B 2 118 ? 113.834 110.840 170.511 1.00 229.16 ? 118 A   B C8    1 
ATOM 5082 N N7    . A   B 2 118 ? 114.329 110.029 171.410 1.00 228.07 ? 118 A   B N7    1 
ATOM 5083 C C5    . A   B 2 118 ? 114.642 108.892 170.684 1.00 229.66 ? 118 A   B C5    1 
ATOM 5084 C C6    . A   B 2 118 ? 115.206 107.662 171.072 1.00 229.58 ? 118 A   B C6    1 
ATOM 5085 N N6    . A   B 2 118 ? 115.560 107.376 172.327 1.00 229.11 ? 118 A   B N6    1 
ATOM 5086 N N1    . A   B 2 118 ? 115.397 106.724 170.121 1.00 229.28 ? 118 A   B N1    1 
ATOM 5087 C C2    . A   B 2 118 ? 115.042 107.012 168.864 1.00 228.55 ? 118 A   B C2    1 
ATOM 5088 N N3    . A   B 2 118 ? 114.505 108.129 168.378 1.00 229.29 ? 118 A   B N3    1 
ATOM 5089 C C4    . A   B 2 118 ? 114.325 109.052 169.343 1.00 230.18 ? 118 A   B C4    1 
ATOM 5090 P P     . A   B 2 119 ? 116.127 113.809 165.684 1.00 234.17 ? 119 A   B P     1 
ATOM 5091 O OP1   . A   B 2 119 ? 115.286 114.912 166.218 1.00 236.79 ? 119 A   B OP1   1 
ATOM 5092 O OP2   . A   B 2 119 ? 116.959 114.072 164.484 1.00 226.46 ? 119 A   B OP2   1 
ATOM 5093 O "O5'" . A   B 2 119 ? 117.106 113.301 166.832 1.00 230.23 ? 119 A   B "O5'" 1 
ATOM 5094 C "C5'" . A   B 2 119 ? 118.023 114.196 167.446 1.00 229.55 ? 119 A   B "C5'" 1 
ATOM 5095 C "C4'" . A   B 2 119 ? 118.107 113.963 168.933 1.00 230.92 ? 119 A   B "C4'" 1 
ATOM 5096 O "O4'" . A   B 2 119 ? 117.398 112.746 169.270 1.00 230.88 ? 119 A   B "O4'" 1 
ATOM 5097 C "C3'" . A   B 2 119 ? 119.508 113.759 169.489 1.00 231.61 ? 119 A   B "C3'" 1 
ATOM 5098 O "O3'" . A   B 2 119 ? 120.154 114.990 169.770 1.00 234.31 ? 119 A   B "O3'" 1 
ATOM 5099 C "C2'" . A   B 2 119 ? 119.271 112.906 170.730 1.00 232.07 ? 119 A   B "C2'" 1 
ATOM 5100 O "O2'" . A   B 2 119 ? 118.903 113.718 171.835 1.00 231.91 ? 119 A   B "O2'" 1 
ATOM 5101 C "C1'" . A   B 2 119 ? 118.057 112.071 170.316 1.00 231.29 ? 119 A   B "C1'" 1 
ATOM 5102 N N9    . A   B 2 119 ? 118.407 110.718 169.845 1.00 230.75 ? 119 A   B N9    1 
ATOM 5103 C C8    . A   B 2 119 ? 118.336 110.250 168.557 1.00 228.64 ? 119 A   B C8    1 
ATOM 5104 N N7    . A   B 2 119 ? 118.685 108.995 168.430 1.00 227.45 ? 119 A   B N7    1 
ATOM 5105 C C5    . A   B 2 119 ? 118.999 108.605 169.723 1.00 229.54 ? 119 A   B C5    1 
ATOM 5106 C C6    . A   B 2 119 ? 119.440 107.384 170.262 1.00 228.43 ? 119 A   B C6    1 
ATOM 5107 N N6    . A   B 2 119 ? 119.652 106.286 169.533 1.00 227.17 ? 119 A   B N6    1 
ATOM 5108 N N1    . A   B 2 119 ? 119.661 107.328 171.594 1.00 228.17 ? 119 A   B N1    1 
ATOM 5109 C C2    . A   B 2 119 ? 119.450 108.428 172.329 1.00 228.79 ? 119 A   B C2    1 
ATOM 5110 N N3    . A   B 2 119 ? 119.036 109.632 171.936 1.00 229.89 ? 119 A   B N3    1 
ATOM 5111 C C4    . A   B 2 119 ? 118.825 109.654 170.608 1.00 230.74 ? 119 A   B C4    1 
ATOM 5112 P P     . A   B 2 120 ? 121.666 115.254 169.294 1.00 235.66 ? 120 A   B P     1 
ATOM 5113 O OP1   . A   B 2 120 ? 121.926 116.712 169.400 1.00 234.64 ? 120 A   B OP1   1 
ATOM 5114 O OP2   . A   B 2 120 ? 121.874 114.572 167.994 1.00 228.72 ? 120 A   B OP2   1 
ATOM 5115 O "O5'" . A   B 2 120 ? 122.548 114.523 170.399 1.00 236.87 ? 120 A   B "O5'" 1 
ATOM 5116 C "C5'" . A   B 2 120 ? 122.458 114.900 171.765 1.00 237.38 ? 120 A   B "C5'" 1 
ATOM 5117 C "C4'" . A   B 2 120 ? 122.926 113.792 172.674 1.00 236.25 ? 120 A   B "C4'" 1 
ATOM 5118 O "O4'" . A   B 2 120 ? 122.066 112.634 172.512 1.00 234.49 ? 120 A   B "O4'" 1 
ATOM 5119 C "C3'" . A   B 2 120 ? 124.322 113.257 172.401 1.00 236.16 ? 120 A   B "C3'" 1 
ATOM 5120 O "O3'" . A   B 2 120 ? 125.348 114.054 172.968 1.00 237.58 ? 120 A   B "O3'" 1 
ATOM 5121 C "C2'" . A   B 2 120 ? 124.256 111.850 172.978 1.00 234.16 ? 120 A   B "C2'" 1 
ATOM 5122 O "O2'" . A   B 2 120 ? 124.374 111.882 174.393 1.00 233.50 ? 120 A   B "O2'" 1 
ATOM 5123 C "C1'" . A   B 2 120 ? 122.825 111.449 172.621 1.00 232.93 ? 120 A   B "C1'" 1 
ATOM 5124 N N9    . A   B 2 120 ? 122.764 110.735 171.332 1.00 230.63 ? 120 A   B N9    1 
ATOM 5125 C C8    . A   B 2 120 ? 122.428 111.244 170.102 1.00 228.59 ? 120 A   B C8    1 
ATOM 5126 N N7    . A   B 2 120 ? 122.469 110.360 169.134 1.00 225.81 ? 120 A   B N7    1 
ATOM 5127 C C5    . A   B 2 120 ? 122.861 109.192 169.771 1.00 226.86 ? 120 A   B C5    1 
ATOM 5128 C C6    . A   B 2 120 ? 123.091 107.885 169.304 1.00 225.69 ? 120 A   B C6    1 
ATOM 5129 N N6    . A   B 2 120 ? 122.952 107.523 168.027 1.00 222.07 ? 120 A   B N6    1 
ATOM 5130 N N1    . A   B 2 120 ? 123.474 106.951 170.203 1.00 226.73 ? 120 A   B N1    1 
ATOM 5131 C C2    . A   B 2 120 ? 123.614 107.308 171.487 1.00 228.76 ? 120 A   B C2    1 
ATOM 5132 N N3    . A   B 2 120 ? 123.427 108.503 172.045 1.00 229.93 ? 120 A   B N3    1 
ATOM 5133 C C4    . A   B 2 120 ? 123.048 109.408 171.125 1.00 229.26 ? 120 A   B C4    1 
ATOM 5134 P P     . U   B 2 121 ? 126.383 114.846 172.026 1.00 238.96 ? 121 U   B P     1 
ATOM 5135 O OP1   . U   B 2 121 ? 127.466 115.379 172.891 1.00 237.95 ? 121 U   B OP1   1 
ATOM 5136 O OP2   . U   B 2 121 ? 125.606 115.777 171.169 1.00 237.23 ? 121 U   B OP2   1 
ATOM 5137 O "O5'" . U   B 2 121 ? 127.008 113.721 171.084 1.00 237.35 ? 121 U   B "O5'" 1 
ATOM 5138 C "C5'" . U   B 2 121 ? 127.824 112.685 171.614 1.00 236.65 ? 121 U   B "C5'" 1 
ATOM 5139 C "C4'" . U   B 2 121 ? 127.654 111.402 170.840 1.00 234.23 ? 121 U   B "C4'" 1 
ATOM 5140 O "O4'" . U   B 2 121 ? 126.273 111.269 170.405 1.00 232.73 ? 121 U   B "O4'" 1 
ATOM 5141 C "C3'" . U   B 2 121 ? 128.450 111.291 169.550 1.00 230.72 ? 121 U   B "C3'" 1 
ATOM 5142 O "O3'" . U   B 2 121 ? 129.807 110.945 169.755 1.00 233.17 ? 121 U   B "O3'" 1 
ATOM 5143 C "C2'" . U   B 2 121 ? 127.659 110.252 168.767 1.00 225.67 ? 121 U   B "C2'" 1 
ATOM 5144 O "O2'" . U   B 2 121 ? 127.931 108.945 169.250 1.00 224.18 ? 121 U   B "O2'" 1 
ATOM 5145 C "C1'" . U   B 2 121 ? 126.224 110.619 169.150 1.00 227.21 ? 121 U   B "C1'" 1 
ATOM 5146 N N1    . U   B 2 121 ? 125.592 111.527 168.159 1.00 224.58 ? 121 U   B N1    1 
ATOM 5147 C C2    . U   B 2 121 ? 125.099 110.992 166.976 1.00 218.94 ? 121 U   B C2    1 
ATOM 5148 O O2    . U   B 2 121 ? 125.155 109.805 166.703 1.00 216.22 ? 121 U   B O2    1 
ATOM 5149 N N3    . U   B 2 121 ? 124.531 111.906 166.115 1.00 216.45 ? 121 U   B N3    1 
ATOM 5150 C C4    . U   B 2 121 ? 124.411 113.269 166.312 1.00 218.40 ? 121 U   B C4    1 
ATOM 5151 O O4    . U   B 2 121 ? 123.875 113.977 165.458 1.00 215.07 ? 121 U   B O4    1 
ATOM 5152 C C5    . U   B 2 121 ? 124.939 113.741 167.552 1.00 224.60 ? 121 U   B C5    1 
ATOM 5153 C C6    . U   B 2 121 ? 125.491 112.878 168.406 1.00 226.67 ? 121 U   B C6    1 
ATOM 5154 P P     . G   B 2 122 ? 130.926 111.457 168.722 1.00 233.88 ? 122 G   B P     1 
ATOM 5155 O OP1   . G   B 2 122 ? 132.258 111.155 169.305 1.00 230.05 ? 122 G   B OP1   1 
ATOM 5156 O OP2   . G   B 2 122 ? 130.592 112.848 168.325 1.00 232.28 ? 122 G   B OP2   1 
ATOM 5157 O "O5'" . G   B 2 122 ? 130.724 110.523 167.448 1.00 224.60 ? 122 G   B "O5'" 1 
ATOM 5158 C "C5'" . G   B 2 122 ? 131.043 109.143 167.510 1.00 220.38 ? 122 G   B "C5'" 1 
ATOM 5159 C "C4'" . G   B 2 122 ? 130.667 108.422 166.241 1.00 215.13 ? 122 G   B "C4'" 1 
ATOM 5160 O "O4'" . G   B 2 122 ? 129.217 108.402 166.095 1.00 212.17 ? 122 G   B "O4'" 1 
ATOM 5161 C "C3'" . G   B 2 122 ? 131.132 109.056 164.942 1.00 211.73 ? 122 G   B "C3'" 1 
ATOM 5162 O "O3'" . G   B 2 122 ? 132.547 109.021 164.706 1.00 215.24 ? 122 G   B "O3'" 1 
ATOM 5163 C "C2'" . G   B 2 122 ? 130.174 108.426 163.930 1.00 207.15 ? 122 G   B "C2'" 1 
ATOM 5164 O "O2'" . G   B 2 122 ? 130.435 107.044 163.727 1.00 207.24 ? 122 G   B "O2'" 1 
ATOM 5165 C "C1'" . G   B 2 122 ? 128.873 108.505 164.722 1.00 206.73 ? 122 G   B "C1'" 1 
ATOM 5166 N N9    . G   B 2 122 ? 128.205 109.799 164.499 1.00 204.87 ? 122 G   B N9    1 
ATOM 5167 C C8    . G   B 2 122 ? 128.138 110.860 165.368 1.00 210.54 ? 122 G   B C8    1 
ATOM 5168 N N7    . G   B 2 122 ? 127.492 111.882 164.881 1.00 208.21 ? 122 G   B N7    1 
ATOM 5169 C C5    . G   B 2 122 ? 127.116 111.473 163.611 1.00 201.26 ? 122 G   B C5    1 
ATOM 5170 C C6    . G   B 2 122 ? 126.401 112.167 162.606 1.00 198.06 ? 122 G   B C6    1 
ATOM 5171 O O6    . G   B 2 122 ? 125.925 113.307 162.661 1.00 199.23 ? 122 G   B O6    1 
ATOM 5172 N N1    . G   B 2 122 ? 126.229 111.391 161.464 1.00 194.35 ? 122 G   B N1    1 
ATOM 5173 C C2    . G   B 2 122 ? 126.705 110.112 161.307 1.00 192.90 ? 122 G   B C2    1 
ATOM 5174 N N2    . G   B 2 122 ? 126.448 109.524 160.130 1.00 192.09 ? 122 G   B N2    1 
ATOM 5175 N N3    . G   B 2 122 ? 127.382 109.455 162.235 1.00 192.98 ? 122 G   B N3    1 
ATOM 5176 C C4    . G   B 2 122 ? 127.551 110.192 163.355 1.00 198.91 ? 122 G   B C4    1 
ATOM 5177 P P     . G   B 2 123 ? 133.320 107.939 163.794 1.00 218.56 ? 123 G   B P     1 
ATOM 5178 O OP1   . G   B 2 123 ? 132.844 106.574 164.136 1.00 215.89 ? 123 G   B OP1   1 
ATOM 5179 O OP2   . G   B 2 123 ? 134.767 108.242 163.914 1.00 215.29 ? 123 G   B OP2   1 
ATOM 5180 O "O5'" . G   B 2 123 ? 132.896 108.278 162.295 1.00 208.98 ? 123 G   B "O5'" 1 
ATOM 5181 C "C5'" . G   B 2 123 ? 132.828 107.240 161.330 1.00 204.09 ? 123 G   B "C5'" 1 
ATOM 5182 C "C4'" . G   B 2 123 ? 132.080 107.643 160.082 1.00 198.91 ? 123 G   B "C4'" 1 
ATOM 5183 O "O4'" . G   B 2 123 ? 130.741 108.105 160.397 1.00 197.26 ? 123 G   B "O4'" 1 
ATOM 5184 C "C3'" . G   B 2 123 ? 132.654 108.780 159.260 1.00 195.28 ? 123 G   B "C3'" 1 
ATOM 5185 O "O3'" . G   B 2 123 ? 133.800 108.423 158.509 1.00 196.73 ? 123 G   B "O3'" 1 
ATOM 5186 C "C2'" . G   B 2 123 ? 131.463 109.168 158.396 1.00 191.74 ? 123 G   B "C2'" 1 
ATOM 5187 O "O2'" . G   B 2 123 ? 131.288 108.235 157.340 1.00 187.72 ? 123 G   B "O2'" 1 
ATOM 5188 C "C1'" . G   B 2 123 ? 130.308 108.999 159.386 1.00 193.17 ? 123 G   B "C1'" 1 
ATOM 5189 N N9    . G   B 2 123 ? 129.916 110.292 159.980 1.00 192.40 ? 123 G   B N9    1 
ATOM 5190 C C8    . G   B 2 123 ? 130.091 110.752 161.261 1.00 194.57 ? 123 G   B C8    1 
ATOM 5191 N N7    . G   B 2 123 ? 129.624 111.962 161.435 1.00 192.47 ? 123 G   B N7    1 
ATOM 5192 C C5    . G   B 2 123 ? 129.119 112.328 160.193 1.00 189.67 ? 123 G   B C5    1 
ATOM 5193 C C6    . G   B 2 123 ? 128.493 113.528 159.752 1.00 187.15 ? 123 G   B C6    1 
ATOM 5194 O O6    . G   B 2 123 ? 128.238 114.551 160.401 1.00 186.17 ? 123 G   B O6    1 
ATOM 5195 N N1    . G   B 2 123 ? 128.141 113.467 158.405 1.00 184.67 ? 123 G   B N1    1 
ATOM 5196 C C2    . G   B 2 123 ? 128.368 112.386 157.591 1.00 182.12 ? 123 G   B C2    1 
ATOM 5197 N N2    . G   B 2 123 ? 127.965 112.493 156.319 1.00 178.35 ? 123 G   B N2    1 
ATOM 5198 N N3    . G   B 2 123 ? 128.947 111.271 157.986 1.00 184.03 ? 123 G   B N3    1 
ATOM 5199 C C4    . G   B 2 123 ? 129.297 111.307 159.287 1.00 188.75 ? 123 G   B C4    1 
ATOM 5200 P P     . C   B 2 124 ? 134.875 109.550 158.109 1.00 199.53 ? 124 C   B P     1 
ATOM 5201 O OP1   . C   B 2 124 ? 136.047 108.858 157.516 1.00 195.87 ? 124 C   B OP1   1 
ATOM 5202 O OP2   . C   B 2 124 ? 135.068 110.438 159.284 1.00 194.06 ? 124 C   B OP2   1 
ATOM 5203 O "O5'" . C   B 2 124 ? 134.152 110.397 156.963 1.00 194.63 ? 124 C   B "O5'" 1 
ATOM 5204 C "C5'" . C   B 2 124 ? 133.878 109.812 155.698 1.00 189.65 ? 124 C   B "C5'" 1 
ATOM 5205 C "C4'" . C   B 2 124 ? 133.007 110.685 154.823 1.00 182.44 ? 124 C   B "C4'" 1 
ATOM 5206 O "O4'" . C   B 2 124 ? 131.788 111.079 155.515 1.00 181.97 ? 124 C   B "O4'" 1 
ATOM 5207 C "C3'" . C   B 2 124 ? 133.593 112.009 154.364 1.00 179.67 ? 124 C   B "C3'" 1 
ATOM 5208 O "O3'" . C   B 2 124 ? 134.550 111.880 153.329 1.00 180.48 ? 124 C   B "O3'" 1 
ATOM 5209 C "C2'" . C   B 2 124 ? 132.347 112.769 153.940 1.00 177.10 ? 124 C   B "C2'" 1 
ATOM 5210 O "O2'" . C   B 2 124 ? 131.883 112.306 152.682 1.00 177.05 ? 124 C   B "O2'" 1 
ATOM 5211 C "C1'" . C   B 2 124 ? 131.348 112.333 155.019 1.00 179.06 ? 124 C   B "C1'" 1 
ATOM 5212 N N1    . C   B 2 124 ? 131.285 113.311 156.135 1.00 177.38 ? 124 C   B N1    1 
ATOM 5213 C C2    . C   B 2 124 ? 130.733 114.598 155.948 1.00 173.99 ? 124 C   B C2    1 
ATOM 5214 O O2    . C   B 2 124 ? 130.272 114.926 154.840 1.00 172.75 ? 124 C   B O2    1 
ATOM 5215 N N3    . C   B 2 124 ? 130.711 115.465 156.991 1.00 173.71 ? 124 C   B N3    1 
ATOM 5216 C C4    . C   B 2 124 ? 131.202 115.104 158.176 1.00 174.89 ? 124 C   B C4    1 
ATOM 5217 N N4    . C   B 2 124 ? 131.163 115.984 159.180 1.00 173.87 ? 124 C   B N4    1 
ATOM 5218 C C5    . C   B 2 124 ? 131.763 113.815 158.393 1.00 179.69 ? 124 C   B C5    1 
ATOM 5219 C C6    . C   B 2 124 ? 131.784 112.966 157.360 1.00 181.15 ? 124 C   B C6    1 
ATOM 5220 P P     . G   B 2 125 ? 135.778 112.915 153.224 1.00 181.33 ? 125 G   B P     1 
ATOM 5221 O OP1   . G   B 2 125 ? 136.416 112.692 151.904 1.00 175.00 ? 125 G   B OP1   1 
ATOM 5222 O OP2   . G   B 2 125 ? 136.591 112.826 154.463 1.00 180.29 ? 125 G   B OP2   1 
ATOM 5223 O "O5'" . G   B 2 125 ? 135.092 114.354 153.185 1.00 173.57 ? 125 G   B "O5'" 1 
ATOM 5224 C "C5'" . G   B 2 125 ? 134.718 114.941 151.947 1.00 169.91 ? 125 G   B "C5'" 1 
ATOM 5225 C "C4'" . G   B 2 125 ? 133.895 116.193 152.135 1.00 166.80 ? 125 G   B "C4'" 1 
ATOM 5226 O "O4'" . G   B 2 125 ? 132.974 116.030 153.247 1.00 165.10 ? 125 G   B "O4'" 1 
ATOM 5227 C "C3'" . G   B 2 125 ? 134.655 117.462 152.484 1.00 165.30 ? 125 G   B "C3'" 1 
ATOM 5228 O "O3'" . G   B 2 125 ? 135.290 118.067 151.370 1.00 168.18 ? 125 G   B "O3'" 1 
ATOM 5229 C "C2'" . G   B 2 125 ? 133.563 118.323 153.097 1.00 162.92 ? 125 G   B "C2'" 1 
ATOM 5230 O "O2'" . G   B 2 125 ? 132.726 118.863 152.086 1.00 161.73 ? 125 G   B "O2'" 1 
ATOM 5231 C "C1'" . G   B 2 125 ? 132.764 117.279 153.878 1.00 160.83 ? 125 G   B "C1'" 1 
ATOM 5232 N N9    . G   B 2 125 ? 133.203 117.188 155.286 1.00 159.00 ? 125 G   B N9    1 
ATOM 5233 C C8    . G   B 2 125 ? 133.677 116.064 155.918 1.00 160.52 ? 125 G   B C8    1 
ATOM 5234 N N7    . G   B 2 125 ? 133.989 116.266 157.167 1.00 157.73 ? 125 G   B N7    1 
ATOM 5235 C C5    . G   B 2 125 ? 133.708 117.606 157.383 1.00 156.70 ? 125 G   B C5    1 
ATOM 5236 C C6    . G   B 2 125 ? 133.866 118.398 158.551 1.00 154.86 ? 125 G   B C6    1 
ATOM 5237 O O6    . G   B 2 125 ? 134.277 118.059 159.666 1.00 149.77 ? 125 G   B O6    1 
ATOM 5238 N N1    . G   B 2 125 ? 133.471 119.713 158.343 1.00 157.81 ? 125 G   B N1    1 
ATOM 5239 C C2    . G   B 2 125 ? 132.994 120.207 157.158 1.00 159.77 ? 125 G   B C2    1 
ATOM 5240 N N2    . G   B 2 125 ? 132.665 121.506 157.151 1.00 160.88 ? 125 G   B N2    1 
ATOM 5241 N N3    . G   B 2 125 ? 132.848 119.484 156.063 1.00 160.30 ? 125 G   B N3    1 
ATOM 5242 C C4    . G   B 2 125 ? 133.224 118.196 156.234 1.00 158.45 ? 125 G   B C4    1 
ATOM 5243 P P     . C   B 2 126 ? 136.735 118.759 151.530 1.00 169.86 ? 126 C   B P     1 
ATOM 5244 O OP1   . C   B 2 126 ? 136.825 119.842 150.521 1.00 167.57 ? 126 C   B OP1   1 
ATOM 5245 O OP2   . C   B 2 126 ? 137.764 117.690 151.541 1.00 167.27 ? 126 C   B OP2   1 
ATOM 5246 O "O5'" . C   B 2 126 ? 136.700 119.448 152.970 1.00 161.11 ? 126 C   B "O5'" 1 
ATOM 5247 C "C5'" . C   B 2 126 ? 136.240 120.784 153.126 1.00 155.33 ? 126 C   B "C5'" 1 
ATOM 5248 C "C4'" . C   B 2 126 ? 136.437 121.298 154.533 1.00 151.62 ? 126 C   B "C4'" 1 
ATOM 5249 O "O4'" . C   B 2 126 ? 135.829 120.401 155.499 1.00 152.61 ? 126 C   B "O4'" 1 
ATOM 5250 C "C3'" . C   B 2 126 ? 137.872 121.427 155.008 1.00 151.69 ? 126 C   B "C3'" 1 
ATOM 5251 O "O3'" . C   B 2 126 ? 138.508 122.594 154.517 1.00 152.57 ? 126 C   B "O3'" 1 
ATOM 5252 C "C2'" . C   B 2 126 ? 137.722 121.419 156.524 1.00 151.43 ? 126 C   B "C2'" 1 
ATOM 5253 O "O2'" . C   B 2 126 ? 137.336 122.701 156.996 1.00 152.05 ? 126 C   B "O2'" 1 
ATOM 5254 C "C1'" . C   B 2 126 ? 136.543 120.457 156.718 1.00 151.43 ? 126 C   B "C1'" 1 
ATOM 5255 N N1    . C   B 2 126 ? 136.960 119.084 157.102 1.00 151.46 ? 126 C   B N1    1 
ATOM 5256 C C2    . C   B 2 126 ? 137.520 118.799 158.368 1.00 149.84 ? 126 C   B C2    1 
ATOM 5257 O O2    . C   B 2 126 ? 137.709 119.713 159.189 1.00 147.38 ? 126 C   B O2    1 
ATOM 5258 N N3    . C   B 2 126 ? 137.874 117.522 158.661 1.00 149.92 ? 126 C   B N3    1 
ATOM 5259 C C4    . C   B 2 126 ? 137.675 116.550 157.771 1.00 151.14 ? 126 C   B C4    1 
ATOM 5260 N N4    . C   B 2 126 ? 138.027 115.303 158.096 1.00 150.65 ? 126 C   B N4    1 
ATOM 5261 C C5    . C   B 2 126 ? 137.095 116.806 156.497 1.00 151.95 ? 126 C   B C5    1 
ATOM 5262 C C6    . C   B 2 126 ? 136.760 118.068 156.212 1.00 151.39 ? 126 C   B C6    1 
ATOM 5263 P P     . C   B 2 127 ? 140.093 122.605 154.252 1.00 148.61 ? 127 C   B P     1 
ATOM 5264 O OP1   . C   B 2 127 ? 140.431 123.906 153.623 1.00 140.54 ? 127 C   B OP1   1 
ATOM 5265 O OP2   . C   B 2 127 ? 140.455 121.343 153.559 1.00 148.41 ? 127 C   B OP2   1 
ATOM 5266 O "O5'" . C   B 2 127 ? 140.732 122.588 155.713 1.00 145.37 ? 127 C   B "O5'" 1 
ATOM 5267 C "C5'" . C   B 2 127 ? 140.727 123.755 156.521 1.00 140.71 ? 127 C   B "C5'" 1 
ATOM 5268 C "C4'" . C   B 2 127 ? 141.371 123.515 157.863 1.00 137.70 ? 127 C   B "C4'" 1 
ATOM 5269 O "O4'" . C   B 2 127 ? 140.630 122.504 158.596 1.00 138.62 ? 127 C   B "O4'" 1 
ATOM 5270 C "C3'" . C   B 2 127 ? 142.795 122.982 157.843 1.00 140.56 ? 127 C   B "C3'" 1 
ATOM 5271 O "O3'" . C   B 2 127 ? 143.768 123.987 157.617 1.00 141.12 ? 127 C   B "O3'" 1 
ATOM 5272 C "C2'" . C   B 2 127 ? 142.919 122.326 159.209 1.00 141.96 ? 127 C   B "C2'" 1 
ATOM 5273 O "O2'" . C   B 2 127 ? 143.147 123.301 160.215 1.00 140.13 ? 127 C   B "O2'" 1 
ATOM 5274 C "C1'" . C   B 2 127 ? 141.514 121.750 159.401 1.00 142.41 ? 127 C   B "C1'" 1 
ATOM 5275 N N1    . C   B 2 127 ? 141.423 120.321 159.010 1.00 142.63 ? 127 C   B N1    1 
ATOM 5276 C C2    . C   B 2 127 ? 141.984 119.323 159.825 1.00 144.40 ? 127 C   B C2    1 
ATOM 5277 O O2    . C   B 2 127 ? 142.577 119.647 160.866 1.00 145.84 ? 127 C   B O2    1 
ATOM 5278 N N3    . C   B 2 127 ? 141.884 118.026 159.440 1.00 143.63 ? 127 C   B N3    1 
ATOM 5279 C C4    . C   B 2 127 ? 141.248 117.704 158.315 1.00 141.42 ? 127 C   B C4    1 
ATOM 5280 N N4    . C   B 2 127 ? 141.164 116.417 157.972 1.00 140.61 ? 127 C   B N4    1 
ATOM 5281 C C5    . C   B 2 127 ? 140.670 118.693 157.475 1.00 141.78 ? 127 C   B C5    1 
ATOM 5282 C C6    . C   B 2 127 ? 140.770 119.968 157.863 1.00 141.86 ? 127 C   B C6    1 
ATOM 5283 P P     . U   B 2 128 ? 145.195 123.606 156.980 1.00 144.67 ? 128 U   B P     1 
ATOM 5284 O OP1   . U   B 2 128 ? 145.926 124.874 156.730 1.00 144.47 ? 128 U   B OP1   1 
ATOM 5285 O OP2   . U   B 2 128 ? 144.958 122.666 155.856 1.00 135.13 ? 128 U   B OP2   1 
ATOM 5286 O "O5'" . U   B 2 128 ? 145.960 122.819 158.139 1.00 144.15 ? 128 U   B "O5'" 1 
ATOM 5287 C "C5'" . U   B 2 128 ? 146.488 123.503 159.267 1.00 139.63 ? 128 U   B "C5'" 1 
ATOM 5288 C "C4'" . U   B 2 128 ? 147.137 122.556 160.247 1.00 137.39 ? 128 U   B "C4'" 1 
ATOM 5289 O "O4'" . U   B 2 128 ? 146.168 121.574 160.699 1.00 134.90 ? 128 U   B "O4'" 1 
ATOM 5290 C "C3'" . U   B 2 128 ? 148.289 121.717 159.713 1.00 140.07 ? 128 U   B "C3'" 1 
ATOM 5291 O "O3'" . U   B 2 128 ? 149.521 122.415 159.682 1.00 145.21 ? 128 U   B "O3'" 1 
ATOM 5292 C "C2'" . U   B 2 128 ? 148.299 120.525 160.659 1.00 136.68 ? 128 U   B "C2'" 1 
ATOM 5293 O "O2'" . U   B 2 128 ? 148.940 120.860 161.881 1.00 132.74 ? 128 U   B "O2'" 1 
ATOM 5294 C "C1'" . U   B 2 128 ? 146.808 120.335 160.930 1.00 137.67 ? 128 U   B "C1'" 1 
ATOM 5295 N N1    . U   B 2 128 ? 146.195 119.310 160.051 1.00 137.53 ? 128 U   B N1    1 
ATOM 5296 C C2    . U   B 2 128 ? 146.442 117.967 160.294 1.00 139.42 ? 128 U   B C2    1 
ATOM 5297 O O2    . U   B 2 128 ? 147.162 117.555 161.187 1.00 141.45 ? 128 U   B O2    1 
ATOM 5298 N N3    . U   B 2 128 ? 145.821 117.100 159.426 1.00 138.98 ? 128 U   B N3    1 
ATOM 5299 C C4    . U   B 2 128 ? 144.988 117.422 158.375 1.00 138.75 ? 128 U   B C4    1 
ATOM 5300 O O4    . U   B 2 128 ? 144.491 116.540 157.675 1.00 138.93 ? 128 U   B O4    1 
ATOM 5301 C C5    . U   B 2 128 ? 144.784 118.822 158.193 1.00 138.87 ? 128 U   B C5    1 
ATOM 5302 C C6    . U   B 2 128 ? 145.368 119.688 159.021 1.00 137.53 ? 128 U   B C6    1 
ATOM 5303 P P     . U   B 2 129 ? 150.671 121.980 158.646 1.00 147.34 ? 129 U   B P     1 
ATOM 5304 O OP1   . U   B 2 129 ? 151.760 122.985 158.728 1.00 147.59 ? 129 U   B OP1   1 
ATOM 5305 O OP2   . U   B 2 129 ? 150.024 121.697 157.341 1.00 139.85 ? 129 U   B OP2   1 
ATOM 5306 O "O5'" . U   B 2 129 ? 151.229 120.600 159.221 1.00 145.12 ? 129 U   B "O5'" 1 
ATOM 5307 C "C5'" . U   B 2 129 ? 152.005 120.557 160.409 1.00 142.46 ? 129 U   B "C5'" 1 
ATOM 5308 C "C4'" . U   B 2 129 ? 152.353 119.138 160.789 1.00 139.20 ? 129 U   B "C4'" 1 
ATOM 5309 O "O4'" . U   B 2 129 ? 151.136 118.377 161.005 1.00 133.88 ? 129 U   B "O4'" 1 
ATOM 5310 C "C3'" . U   B 2 129 ? 153.108 118.334 159.741 1.00 140.13 ? 129 U   B "C3'" 1 
ATOM 5311 O "O3'" . U   B 2 129 ? 154.500 118.597 159.735 1.00 143.66 ? 129 U   B "O3'" 1 
ATOM 5312 C "C2'" . U   B 2 129 ? 152.765 116.898 160.110 1.00 135.24 ? 129 U   B "C2'" 1 
ATOM 5313 O "O2'" . U   B 2 129 ? 153.558 116.456 161.201 1.00 133.80 ? 129 U   B "O2'" 1 
ATOM 5314 C "C1'" . U   B 2 129 ? 151.321 117.040 160.588 1.00 134.88 ? 129 U   B "C1'" 1 
ATOM 5315 N N1    . U   B 2 129 ? 150.326 116.725 159.534 1.00 137.21 ? 129 U   B N1    1 
ATOM 5316 C C2    . U   B 2 129 ? 150.054 115.400 159.229 1.00 137.28 ? 129 U   B C2    1 
ATOM 5317 O O2    . U   B 2 129 ? 150.608 114.459 159.770 1.00 136.99 ? 129 U   B O2    1 
ATOM 5318 N N3    . U   B 2 129 ? 149.104 115.211 158.252 1.00 136.42 ? 129 U   B N3    1 
ATOM 5319 C C4    . U   B 2 129 ? 148.409 116.188 157.568 1.00 136.12 ? 129 U   B C4    1 
ATOM 5320 O O4    . U   B 2 129 ? 147.579 115.883 156.712 1.00 135.32 ? 129 U   B O4    1 
ATOM 5321 C C5    . U   B 2 129 ? 148.743 117.524 157.940 1.00 138.70 ? 129 U   B C5    1 
ATOM 5322 C C6    . U   B 2 129 ? 149.656 117.735 158.887 1.00 138.39 ? 129 U   B C6    1 
ATOM 5323 P P     . C   B 2 130 ? 155.353 118.400 158.387 1.00 152.55 ? 130 C   B P     1 
ATOM 5324 O OP1   . C   B 2 130 ? 156.718 118.930 158.631 1.00 152.84 ? 130 C   B OP1   1 
ATOM 5325 O OP2   . C   B 2 130 ? 154.554 118.930 157.254 1.00 151.58 ? 130 C   B OP2   1 
ATOM 5326 O "O5'" . C   B 2 130 ? 155.460 116.819 158.219 1.00 143.54 ? 130 C   B "O5'" 1 
ATOM 5327 C "C5'" . C   B 2 130 ? 156.229 116.037 159.120 1.00 138.00 ? 130 C   B "C5'" 1 
ATOM 5328 C "C4'" . C   B 2 130 ? 156.009 114.563 158.893 1.00 136.70 ? 130 C   B "C4'" 1 
ATOM 5329 O "O4'" . C   B 2 130 ? 154.601 114.243 159.058 1.00 133.38 ? 130 C   B "O4'" 1 
ATOM 5330 C "C3'" . C   B 2 130 ? 156.337 114.053 157.500 1.00 139.16 ? 130 C   B "C3'" 1 
ATOM 5331 O "O3'" . C   B 2 130 ? 157.721 113.836 157.293 1.00 143.78 ? 130 C   B "O3'" 1 
ATOM 5332 C "C2'" . C   B 2 130 ? 155.492 112.791 157.402 1.00 137.45 ? 130 C   B "C2'" 1 
ATOM 5333 O "O2'" . C   B 2 130 ? 156.108 111.722 158.104 1.00 136.74 ? 130 C   B "O2'" 1 
ATOM 5334 C "C1'" . C   B 2 130 ? 154.233 113.210 158.165 1.00 136.33 ? 130 C   B "C1'" 1 
ATOM 5335 N N1    . C   B 2 130 ? 153.157 113.707 157.266 1.00 137.77 ? 130 C   B N1    1 
ATOM 5336 C C2    . C   B 2 130 ? 152.334 112.803 156.576 1.00 133.81 ? 130 C   B C2    1 
ATOM 5337 O O2    . C   B 2 130 ? 152.522 111.586 156.718 1.00 132.66 ? 130 C   B O2    1 
ATOM 5338 N N3    . C   B 2 130 ? 151.355 113.283 155.766 1.00 131.85 ? 130 C   B N3    1 
ATOM 5339 C C4    . C   B 2 130 ? 151.173 114.596 155.630 1.00 130.96 ? 130 C   B C4    1 
ATOM 5340 N N4    . C   B 2 130 ? 150.202 115.037 154.828 1.00 127.41 ? 130 C   B N4    1 
ATOM 5341 C C5    . C   B 2 130 ? 151.984 115.535 156.318 1.00 136.09 ? 130 C   B C5    1 
ATOM 5342 C C6    . C   B 2 130 ? 152.944 115.048 157.109 1.00 139.03 ? 130 C   B C6    1 
ATOM 5343 P P     . A   B 2 131 ? 158.377 114.159 155.863 1.00 150.67 ? 131 A   B P     1 
ATOM 5344 O OP1   . A   B 2 131 ? 159.853 114.174 156.016 1.00 152.72 ? 131 A   B OP1   1 
ATOM 5345 O OP2   . A   B 2 131 ? 157.683 115.347 155.305 1.00 147.24 ? 131 A   B OP2   1 
ATOM 5346 O "O5'" . A   B 2 131 ? 157.988 112.900 154.971 1.00 141.76 ? 131 A   B "O5'" 1 
ATOM 5347 C "C5'" . A   B 2 131 ? 158.394 111.593 155.344 1.00 138.69 ? 131 A   B "C5'" 1 
ATOM 5348 C "C4'" . A   B 2 131 ? 157.615 110.542 154.597 1.00 135.67 ? 131 A   B "C4'" 1 
ATOM 5349 O "O4'" . A   B 2 131 ? 156.212 110.630 154.948 1.00 131.48 ? 131 A   B "O4'" 1 
ATOM 5350 C "C3'" . A   B 2 131 ? 157.627 110.660 153.082 1.00 136.79 ? 131 A   B "C3'" 1 
ATOM 5351 O "O3'" . A   B 2 131 ? 158.794 110.101 152.504 1.00 141.67 ? 131 A   B "O3'" 1 
ATOM 5352 C "C2'" . A   B 2 131 ? 156.348 109.939 152.678 1.00 134.13 ? 131 A   B "C2'" 1 
ATOM 5353 O "O2'" . A   B 2 131 ? 156.545 108.534 152.669 1.00 135.62 ? 131 A   B "O2'" 1 
ATOM 5354 C "C1'" . A   B 2 131 ? 155.415 110.288 153.836 1.00 133.14 ? 131 A   B "C1'" 1 
ATOM 5355 N N9    . A   B 2 131 ? 154.507 111.413 153.534 1.00 132.61 ? 131 A   B N9    1 
ATOM 5356 C C8    . A   B 2 131 ? 154.546 112.678 154.063 1.00 132.54 ? 131 A   B C8    1 
ATOM 5357 N N7    . A   B 2 131 ? 153.598 113.471 153.635 1.00 127.73 ? 131 A   B N7    1 
ATOM 5358 C C5    . A   B 2 131 ? 152.878 112.670 152.765 1.00 127.23 ? 131 A   B C5    1 
ATOM 5359 C C6    . A   B 2 131 ? 151.746 112.922 151.978 1.00 124.28 ? 131 A   B C6    1 
ATOM 5360 N N6    . A   B 2 131 ? 151.123 114.101 151.951 1.00 122.03 ? 131 A   B N6    1 
ATOM 5361 N N1    . A   B 2 131 ? 151.269 111.914 151.214 1.00 122.93 ? 131 A   B N1    1 
ATOM 5362 C C2    . A   B 2 131 ? 151.893 110.729 151.248 1.00 123.06 ? 131 A   B C2    1 
ATOM 5363 N N3    . A   B 2 131 ? 152.971 110.373 151.947 1.00 124.73 ? 131 A   B N3    1 
ATOM 5364 C C4    . A   B 2 131 ? 153.419 111.398 152.694 1.00 128.04 ? 131 A   B C4    1 
ATOM 5365 P P     . U   B 2 132 ? 159.490 110.798 151.235 1.00 151.22 ? 132 U   B P     1 
ATOM 5366 O OP1   . U   B 2 132 ? 160.812 110.155 151.025 1.00 149.65 ? 132 U   B OP1   1 
ATOM 5367 O OP2   . U   B 2 132 ? 159.411 112.269 151.419 1.00 150.49 ? 132 U   B OP2   1 
ATOM 5368 O "O5'" . U   B 2 132 ? 158.550 110.400 150.012 1.00 143.80 ? 132 U   B "O5'" 1 
ATOM 5369 C "C5'" . U   B 2 132 ? 158.297 109.039 149.697 1.00 140.94 ? 132 U   B "C5'" 1 
ATOM 5370 C "C4'" . U   B 2 132 ? 157.093 108.900 148.803 1.00 136.07 ? 132 U   B "C4'" 1 
ATOM 5371 O "O4'" . U   B 2 132 ? 155.906 109.365 149.495 1.00 128.34 ? 132 U   B "O4'" 1 
ATOM 5372 C "C3'" . U   B 2 132 ? 157.123 109.725 147.529 1.00 134.81 ? 132 U   B "C3'" 1 
ATOM 5373 O "O3'" . U   B 2 132 ? 157.883 109.113 146.502 1.00 138.50 ? 132 U   B "O3'" 1 
ATOM 5374 C "C2'" . U   B 2 132 ? 155.646 109.875 147.188 1.00 132.04 ? 132 U   B "C2'" 1 
ATOM 5375 O "O2'" . U   B 2 132 ? 155.158 108.709 146.541 1.00 136.16 ? 132 U   B "O2'" 1 
ATOM 5376 C "C1'" . U   B 2 132 ? 155.012 109.956 148.577 1.00 127.44 ? 132 U   B "C1'" 1 
ATOM 5377 N N1    . U   B 2 132 ? 154.711 111.343 149.013 1.00 123.18 ? 132 U   B N1    1 
ATOM 5378 C C2    . U   B 2 132 ? 153.553 111.945 148.547 1.00 119.55 ? 132 U   B C2    1 
ATOM 5379 O O2    . U   B 2 132 ? 152.782 111.400 147.777 1.00 119.43 ? 132 U   B O2    1 
ATOM 5380 N N3    . U   B 2 132 ? 153.320 113.219 149.008 1.00 117.52 ? 132 U   B N3    1 
ATOM 5381 C C4    . U   B 2 132 ? 154.112 113.939 149.877 1.00 117.47 ? 132 U   B C4    1 
ATOM 5382 O O4    . U   B 2 132 ? 153.772 115.077 150.204 1.00 114.77 ? 132 U   B O4    1 
ATOM 5383 C C5    . U   B 2 132 ? 155.283 113.250 150.322 1.00 120.91 ? 132 U   B C5    1 
ATOM 5384 C C6    . U   B 2 132 ? 155.533 112.011 149.889 1.00 123.85 ? 132 U   B C6    1 
ATOM 5385 P P     . C   B 2 133 ? 158.646 110.012 145.413 1.00 143.42 ? 133 C   B P     1 
ATOM 5386 O OP1   . C   B 2 133 ? 159.538 109.117 144.633 1.00 147.15 ? 133 C   B OP1   1 
ATOM 5387 O OP2   . C   B 2 133 ? 159.214 111.198 146.102 1.00 135.18 ? 133 C   B OP2   1 
ATOM 5388 O "O5'" . C   B 2 133 ? 157.483 110.505 144.443 1.00 135.66 ? 133 C   B "O5'" 1 
ATOM 5389 C "C5'" . C   B 2 133 ? 156.737 109.573 143.676 1.00 132.82 ? 133 C   B "C5'" 1 
ATOM 5390 C "C4'" . C   B 2 133 ? 155.484 110.195 143.118 1.00 130.09 ? 133 C   B "C4'" 1 
ATOM 5391 O "O4'" . C   B 2 133 ? 154.627 110.649 144.198 1.00 125.96 ? 133 C   B "O4'" 1 
ATOM 5392 C "C3'" . C   B 2 133 ? 155.683 111.438 142.271 1.00 129.67 ? 133 C   B "C3'" 1 
ATOM 5393 O "O3'" . C   B 2 133 ? 156.107 111.150 140.952 1.00 135.96 ? 133 C   B "O3'" 1 
ATOM 5394 C "C2'" . C   B 2 133 ? 154.319 112.110 142.351 1.00 126.02 ? 133 C   B "C2'" 1 
ATOM 5395 O "O2'" . C   B 2 133 ? 153.394 111.479 141.477 1.00 129.11 ? 133 C   B "O2'" 1 
ATOM 5396 C "C1'" . C   B 2 133 ? 153.912 111.798 143.792 1.00 122.16 ? 133 C   B "C1'" 1 
ATOM 5397 N N1    . C   B 2 133 ? 154.207 112.916 144.721 1.00 116.30 ? 133 C   B N1    1 
ATOM 5398 C C2    . C   B 2 133 ? 153.290 113.968 144.815 1.00 109.44 ? 133 C   B C2    1 
ATOM 5399 O O2    . C   B 2 133 ? 152.266 113.942 144.120 1.00 110.06 ? 133 C   B O2    1 
ATOM 5400 N N3    . C   B 2 133 ? 153.535 114.995 145.658 1.00 103.59 ? 133 C   B N3    1 
ATOM 5401 C C4    . C   B 2 133 ? 154.642 115.005 146.395 1.00 105.85 ? 133 C   B C4    1 
ATOM 5402 N N4    . C   B 2 133 ? 154.838 116.042 147.210 1.00 104.42 ? 133 C   B N4    1 
ATOM 5403 C C5    . C   B 2 133 ? 155.596 113.952 146.327 1.00 112.21 ? 133 C   B C5    1 
ATOM 5404 C C6    . C   B 2 133 ? 155.339 112.944 145.486 1.00 117.54 ? 133 C   B C6    1 
ATOM 5405 P P     . G   B 2 134 ? 157.473 111.787 140.401 1.00 139.28 ? 134 G   B P     1 
ATOM 5406 O OP1   . G   B 2 134 ? 157.722 111.240 139.043 1.00 137.38 ? 134 G   B OP1   1 
ATOM 5407 O OP2   . G   B 2 134 ? 158.502 111.639 141.461 1.00 131.86 ? 134 G   B OP2   1 
ATOM 5408 O "O5'" . G   B 2 134 ? 157.139 113.337 140.256 1.00 126.11 ? 134 G   B "O5'" 1 
ATOM 5409 C "C5'" . G   B 2 134 ? 156.787 113.894 138.999 1.00 119.76 ? 134 G   B "C5'" 1 
ATOM 5410 C "C4'" . G   B 2 134 ? 155.430 114.548 139.047 1.00 115.40 ? 134 G   B "C4'" 1 
ATOM 5411 O "O4'" . G   B 2 134 ? 154.954 114.591 140.410 1.00 115.14 ? 134 G   B "O4'" 1 
ATOM 5412 C "C3'" . G   B 2 134 ? 155.370 115.993 138.582 1.00 108.11 ? 134 G   B "C3'" 1 
ATOM 5413 O "O3'" . G   B 2 134 ? 155.269 116.088 137.173 1.00 112.60 ? 134 G   B "O3'" 1 
ATOM 5414 C "C2'" . G   B 2 134 ? 154.146 116.544 139.306 1.00 106.27 ? 134 G   B "C2'" 1 
ATOM 5415 O "O2'" . G   B 2 134 ? 152.963 116.272 138.570 1.00 106.84 ? 134 G   B "O2'" 1 
ATOM 5416 C "C1'" . G   B 2 134 ? 154.119 115.709 140.593 1.00 110.88 ? 134 G   B "C1'" 1 
ATOM 5417 N N9    . G   B 2 134 ? 154.533 116.433 141.815 1.00 107.51 ? 134 G   B N9    1 
ATOM 5418 C C8    . G   B 2 134 ? 155.467 115.994 142.720 1.00 104.12 ? 134 G   B C8    1 
ATOM 5419 N N7    . G   B 2 134 ? 155.628 116.794 143.737 1.00 98.75  ? 134 G   B N7    1 
ATOM 5420 C C5    . G   B 2 134 ? 154.728 117.822 143.510 1.00 97.70  ? 134 G   B C5    1 
ATOM 5421 C C6    . G   B 2 134 ? 154.454 118.986 144.276 1.00 93.44  ? 134 G   B C6    1 
ATOM 5422 O O6    . G   B 2 134 ? 154.962 119.341 145.346 1.00 92.35  ? 134 G   B O6    1 
ATOM 5423 N N1    . G   B 2 134 ? 153.467 119.771 143.690 1.00 93.11  ? 134 G   B N1    1 
ATOM 5424 C C2    . G   B 2 134 ? 152.839 119.469 142.511 1.00 95.92  ? 134 G   B C2    1 
ATOM 5425 N N2    . G   B 2 134 ? 151.913 120.332 142.081 1.00 93.89  ? 134 G   B N2    1 
ATOM 5426 N N3    . G   B 2 134 ? 153.083 118.394 141.791 1.00 100.94 ? 134 G   B N3    1 
ATOM 5427 C C4    . G   B 2 134 ? 154.034 117.611 142.337 1.00 102.69 ? 134 G   B C4    1 
ATOM 5428 P P     . U   B 2 135 ? 155.940 117.315 136.387 1.00 116.17 ? 135 U   B P     1 
ATOM 5429 O OP1   . U   B 2 135 ? 155.781 117.064 134.932 1.00 113.62 ? 135 U   B OP1   1 
ATOM 5430 O OP2   . U   B 2 135 ? 157.291 117.543 136.955 1.00 111.53 ? 135 U   B OP2   1 
ATOM 5431 O "O5'" . U   B 2 135 ? 155.026 118.559 136.768 1.00 105.87 ? 135 U   B "O5'" 1 
ATOM 5432 C "C5'" . U   B 2 135 ? 153.692 118.670 136.283 1.00 98.81  ? 135 U   B "C5'" 1 
ATOM 5433 C "C4'" . U   B 2 135 ? 153.001 119.897 136.826 1.00 89.27  ? 135 U   B "C4'" 1 
ATOM 5434 O "O4'" . U   B 2 135 ? 153.211 119.967 138.261 1.00 88.54  ? 135 U   B "O4'" 1 
ATOM 5435 C "C3'" . U   B 2 135 ? 153.491 121.233 136.264 1.00 84.28  ? 135 U   B "C3'" 1 
ATOM 5436 O "O3'" . U   B 2 135 ? 152.419 122.174 136.292 1.00 81.57  ? 135 U   B "O3'" 1 
ATOM 5437 C "C2'" . U   B 2 135 ? 154.507 121.668 137.312 1.00 83.85  ? 135 U   B "C2'" 1 
ATOM 5438 O "O2'" . U   B 2 135 ? 154.771 123.054 137.337 1.00 81.70  ? 135 U   B "O2'" 1 
ATOM 5439 C "C1'" . U   B 2 135 ? 153.814 121.203 138.587 1.00 84.94  ? 135 U   B "C1'" 1 
ATOM 5440 N N1    . U   B 2 135 ? 154.695 121.005 139.742 1.00 88.82  ? 135 U   B N1    1 
ATOM 5441 C C2    . U   B 2 135 ? 154.610 121.960 140.726 1.00 86.89  ? 135 U   B C2    1 
ATOM 5442 O O2    . U   B 2 135 ? 153.865 122.918 140.642 1.00 83.57  ? 135 U   B O2    1 
ATOM 5443 N N3    . U   B 2 135 ? 155.421 121.765 141.808 1.00 88.82  ? 135 U   B N3    1 
ATOM 5444 C C4    . U   B 2 135 ? 156.297 120.717 141.992 1.00 91.60  ? 135 U   B C4    1 
ATOM 5445 O O4    . U   B 2 135 ? 156.972 120.671 143.020 1.00 93.03  ? 135 U   B O4    1 
ATOM 5446 C C5    . U   B 2 135 ? 156.325 119.760 140.927 1.00 94.63  ? 135 U   B C5    1 
ATOM 5447 C C6    . U   B 2 135 ? 155.537 119.929 139.860 1.00 95.37  ? 135 U   B C6    1 
ATOM 5448 P P     . G   B 2 136 ? 151.303 122.256 135.138 1.00 76.92  ? 136 G   B P     1 
ATOM 5449 O OP1   . G   B 2 136 ? 151.109 120.945 134.473 1.00 76.55  ? 136 G   B OP1   1 
ATOM 5450 O OP2   . G   B 2 136 ? 151.605 123.447 134.307 1.00 81.12  ? 136 G   B OP2   1 
ATOM 5451 O "O5'" . G   B 2 136 ? 149.984 122.583 135.965 1.00 73.89  ? 136 G   B "O5'" 1 
ATOM 5452 C "C5'" . G   B 2 136 ? 149.485 121.651 136.912 1.00 73.45  ? 136 G   B "C5'" 1 
ATOM 5453 C "C4'" . G   B 2 136 ? 149.437 122.220 138.310 1.00 69.15  ? 136 G   B "C4'" 1 
ATOM 5454 O "O4'" . G   B 2 136 ? 150.775 122.509 138.796 1.00 66.37  ? 136 G   B "O4'" 1 
ATOM 5455 C "C3'" . G   B 2 136 ? 148.711 123.538 138.491 1.00 64.16  ? 136 G   B "C3'" 1 
ATOM 5456 O "O3'" . G   B 2 136 ? 147.304 123.425 138.475 1.00 61.70  ? 136 G   B "O3'" 1 
ATOM 5457 C "C2'" . G   B 2 136 ? 149.265 124.020 139.819 1.00 61.79  ? 136 G   B "C2'" 1 
ATOM 5458 O "O2'" . G   B 2 136 ? 148.695 123.286 140.891 1.00 65.93  ? 136 G   B "O2'" 1 
ATOM 5459 C "C1'" . G   B 2 136 ? 150.727 123.609 139.686 1.00 62.94  ? 136 G   B "C1'" 1 
ATOM 5460 N N9    . G   B 2 136 ? 151.534 124.711 139.134 1.00 63.10  ? 136 G   B N9    1 
ATOM 5461 C C8    . G   B 2 136 ? 152.123 124.776 137.899 1.00 70.68  ? 136 G   B C8    1 
ATOM 5462 N N7    . G   B 2 136 ? 152.766 125.892 137.696 1.00 69.11  ? 136 G   B N7    1 
ATOM 5463 C C5    . G   B 2 136 ? 152.585 126.611 138.867 1.00 61.79  ? 136 G   B C5    1 
ATOM 5464 C C6    . G   B 2 136 ? 153.045 127.900 139.234 1.00 61.99  ? 136 G   B C6    1 
ATOM 5465 O O6    . G   B 2 136 ? 153.738 128.693 138.588 1.00 64.52  ? 136 G   B O6    1 
ATOM 5466 N N1    . G   B 2 136 ? 152.632 128.242 140.511 1.00 58.73  ? 136 G   B N1    1 
ATOM 5467 C C2    . G   B 2 136 ? 151.869 127.457 141.330 1.00 57.18  ? 136 G   B C2    1 
ATOM 5468 N N2    . G   B 2 136 ? 151.573 127.971 142.530 1.00 61.15  ? 136 G   B N2    1 
ATOM 5469 N N3    . G   B 2 136 ? 151.433 126.258 141.000 1.00 57.98  ? 136 G   B N3    1 
ATOM 5470 C C4    . G   B 2 136 ? 151.824 125.898 139.763 1.00 58.95  ? 136 G   B C4    1 
ATOM 5471 P P     . G   B 2 137 ? 146.428 124.651 137.928 1.00 65.05  ? 137 G   B P     1 
ATOM 5472 O OP1   . G   B 2 137 ? 145.052 124.157 137.702 1.00 60.30  ? 137 G   B OP1   1 
ATOM 5473 O OP2   . G   B 2 137 ? 147.177 125.277 136.810 1.00 59.56  ? 137 G   B OP2   1 
ATOM 5474 O "O5'" . G   B 2 137 ? 146.410 125.689 139.135 1.00 56.27  ? 137 G   B "O5'" 1 
ATOM 5475 C "C5'" . G   B 2 137 ? 145.891 125.325 140.404 1.00 48.73  ? 137 G   B "C5'" 1 
ATOM 5476 C "C4'" . G   B 2 137 ? 146.269 126.330 141.461 1.00 46.94  ? 137 G   B "C4'" 1 
ATOM 5477 O "O4'" . G   B 2 137 ? 147.702 126.554 141.440 1.00 51.66  ? 137 G   B "O4'" 1 
ATOM 5478 C "C3'" . G   B 2 137 ? 145.682 127.720 141.300 1.00 43.26  ? 137 G   B "C3'" 1 
ATOM 5479 O "O3'" . G   B 2 137 ? 144.349 127.811 141.764 1.00 44.79  ? 137 G   B "O3'" 1 
ATOM 5480 C "C2'" . G   B 2 137 ? 146.658 128.580 142.086 1.00 46.43  ? 137 G   B "C2'" 1 
ATOM 5481 O "O2'" . G   B 2 137 ? 146.423 128.450 143.479 1.00 50.76  ? 137 G   B "O2'" 1 
ATOM 5482 C "C1'" . G   B 2 137 ? 147.983 127.900 141.759 1.00 49.56  ? 137 G   B "C1'" 1 
ATOM 5483 N N9    . G   B 2 137 ? 148.648 128.526 140.603 1.00 48.29  ? 137 G   B N9    1 
ATOM 5484 C C8    . G   B 2 137 ? 148.744 128.005 139.340 1.00 54.60  ? 137 G   B C8    1 
ATOM 5485 N N7    . G   B 2 137 ? 149.389 128.778 138.514 1.00 53.37  ? 137 G   B N7    1 
ATOM 5486 C C5    . G   B 2 137 ? 149.743 129.877 139.278 1.00 49.20  ? 137 G   B C5    1 
ATOM 5487 C C6    . G   B 2 137 ? 150.455 131.046 138.916 1.00 51.83  ? 137 G   B C6    1 
ATOM 5488 O O6    . G   B 2 137 ? 150.935 131.336 137.814 1.00 55.55  ? 137 G   B O6    1 
ATOM 5489 N N1    . G   B 2 137 ? 150.600 131.914 139.991 1.00 50.81  ? 137 G   B N1    1 
ATOM 5490 C C2    . G   B 2 137 ? 150.109 131.680 141.250 1.00 50.56  ? 137 G   B C2    1 
ATOM 5491 N N2    . G   B 2 137 ? 150.343 132.635 142.158 1.00 55.58  ? 137 G   B N2    1 
ATOM 5492 N N3    . G   B 2 137 ? 149.439 130.595 141.599 1.00 46.51  ? 137 G   B N3    1 
ATOM 5493 C C4    . G   B 2 137 ? 149.293 129.738 140.570 1.00 47.01  ? 137 G   B C4    1 
ATOM 5494 P P     . G   B 2 138 ? 143.311 128.796 141.038 1.00 42.59  ? 138 G   B P     1 
ATOM 5495 O OP1   . G   B 2 138 ? 141.954 128.479 141.540 1.00 45.92  ? 138 G   B OP1   1 
ATOM 5496 O OP2   . G   B 2 138 ? 143.584 128.763 139.581 1.00 35.93  ? 138 G   B OP2   1 
ATOM 5497 O "O5'" . G   B 2 138 ? 143.708 130.236 141.585 1.00 36.36  ? 138 G   B "O5'" 1 
ATOM 5498 C "C5'" . G   B 2 138 ? 143.686 130.516 142.975 1.00 35.54  ? 138 G   B "C5'" 1 
ATOM 5499 C "C4'" . G   B 2 138 ? 144.160 131.917 143.256 1.00 34.00  ? 138 G   B "C4'" 1 
ATOM 5500 O "O4'" . G   B 2 138 ? 145.582 132.017 143.019 1.00 36.07  ? 138 G   B "O4'" 1 
ATOM 5501 C "C3'" . G   B 2 138 ? 143.562 132.994 142.375 1.00 33.27  ? 138 G   B "C3'" 1 
ATOM 5502 O "O3'" . G   B 2 138 ? 142.286 133.400 142.830 1.00 31.01  ? 138 G   B "O3'" 1 
ATOM 5503 C "C2'" . G   B 2 138 ? 144.607 134.101 142.430 1.00 36.18  ? 138 G   B "C2'" 1 
ATOM 5504 O "O2'" . G   B 2 138 ? 144.456 134.875 143.608 1.00 38.26  ? 138 G   B "O2'" 1 
ATOM 5505 C "C1'" . G   B 2 138 ? 145.902 133.307 142.547 1.00 36.63  ? 138 G   B "C1'" 1 
ATOM 5506 N N9    . G   B 2 138 ? 146.638 133.178 141.278 1.00 41.80  ? 138 G   B N9    1 
ATOM 5507 C C8    . G   B 2 138 ? 146.762 132.021 140.558 1.00 45.93  ? 138 G   B C8    1 
ATOM 5508 N N7    . G   B 2 138 ? 147.493 132.153 139.493 1.00 46.81  ? 138 G   B N7    1 
ATOM 5509 C C5    . G   B 2 138 ? 147.888 133.477 139.519 1.00 45.47  ? 138 G   B C5    1 
ATOM 5510 C C6    . G   B 2 138 ? 148.696 134.184 138.604 1.00 48.49  ? 138 G   B C6    1 
ATOM 5511 O O6    . G   B 2 138 ? 149.238 133.755 137.581 1.00 53.25  ? 138 G   B O6    1 
ATOM 5512 N N1    . G   B 2 138 ? 148.865 135.507 138.982 1.00 48.32  ? 138 G   B N1    1 
ATOM 5513 C C2    . G   B 2 138 ? 148.315 136.080 140.099 1.00 45.88  ? 138 G   B C2    1 
ATOM 5514 N N2    . G   B 2 138 ? 148.597 137.378 140.284 1.00 42.52  ? 138 G   B N2    1 
ATOM 5515 N N3    . G   B 2 138 ? 147.553 135.426 140.963 1.00 47.58  ? 138 G   B N3    1 
ATOM 5516 C C4    . G   B 2 138 ? 147.380 134.132 140.615 1.00 44.40  ? 138 G   B C4    1 
ATOM 5517 P P     . U   B 2 139 ? 141.104 133.671 141.785 1.00 33.98  ? 139 U   B P     1 
ATOM 5518 O OP1   . U   B 2 139 ? 139.824 133.704 142.529 1.00 32.27  ? 139 U   B OP1   1 
ATOM 5519 O OP2   . U   B 2 139 ? 141.276 132.737 140.648 1.00 37.40  ? 139 U   B OP2   1 
ATOM 5520 O "O5'" . U   B 2 139 ? 141.404 135.141 141.265 1.00 34.20  ? 139 U   B "O5'" 1 
ATOM 5521 C "C5'" . U   B 2 139 ? 141.672 136.191 142.179 1.00 32.45  ? 139 U   B "C5'" 1 
ATOM 5522 C "C4'" . U   B 2 139 ? 142.340 137.344 141.485 1.00 33.67  ? 139 U   B "C4'" 1 
ATOM 5523 O "O4'" . U   B 2 139 ? 143.700 136.996 141.150 1.00 36.53  ? 139 U   B "O4'" 1 
ATOM 5524 C "C3'" . U   B 2 139 ? 141.711 137.736 140.165 1.00 34.03  ? 139 U   B "C3'" 1 
ATOM 5525 O "O3'" . U   B 2 139 ? 140.608 138.597 140.369 1.00 37.20  ? 139 U   B "O3'" 1 
ATOM 5526 C "C2'" . U   B 2 139 ? 142.867 138.375 139.403 1.00 33.55  ? 139 U   B "C2'" 1 
ATOM 5527 O "O2'" . U   B 2 139 ? 143.021 139.733 139.781 1.00 38.69  ? 139 U   B "O2'" 1 
ATOM 5528 C "C1'" . U   B 2 139 ? 144.069 137.595 139.933 1.00 34.28  ? 139 U   B "C1'" 1 
ATOM 5529 N N1    . U   B 2 139 ? 144.556 136.533 139.026 1.00 36.58  ? 139 U   B N1    1 
ATOM 5530 C C2    . U   B 2 139 ? 145.583 136.850 138.170 1.00 40.16  ? 139 U   B C2    1 
ATOM 5531 O O2    . U   B 2 139 ? 146.059 137.965 138.107 1.00 48.03  ? 139 U   B O2    1 
ATOM 5532 N N3    . U   B 2 139 ? 146.024 135.821 137.382 1.00 41.76  ? 139 U   B N3    1 
ATOM 5533 C C4    . U   B 2 139 ? 145.557 134.528 137.369 1.00 42.38  ? 139 U   B C4    1 
ATOM 5534 O O4    . U   B 2 139 ? 146.053 133.709 136.598 1.00 46.64  ? 139 U   B O4    1 
ATOM 5535 C C5    . U   B 2 139 ? 144.505 134.269 138.294 1.00 42.38  ? 139 U   B C5    1 
ATOM 5536 C C6    . U   B 2 139 ? 144.060 135.256 139.073 1.00 41.26  ? 139 U   B C6    1 
ATOM 5537 P P     . U   B 2 140 ? 139.554 138.863 139.199 1.00 26.79  ? 140 U   B P     1 
ATOM 5538 O OP1   . U   B 2 140 ? 138.303 139.382 139.802 1.00 32.24  ? 140 U   B OP1   1 
ATOM 5539 O OP2   . U   B 2 140 ? 139.512 137.664 138.330 1.00 29.46  ? 140 U   B OP2   1 
ATOM 5540 O "O5'" . U   B 2 140 ? 140.217 140.055 138.392 1.00 37.79  ? 140 U   B "O5'" 1 
ATOM 5541 C "C5'" . U   B 2 140 ? 139.921 140.241 137.025 1.00 38.68  ? 140 U   B "C5'" 1 
ATOM 5542 C "C4'" . U   B 2 140 ? 141.111 140.763 136.267 1.00 33.49  ? 140 U   B "C4'" 1 
ATOM 5543 O "O4'" . U   B 2 140 ? 142.240 139.879 136.466 1.00 34.39  ? 140 U   B "O4'" 1 
ATOM 5544 C "C3'" . U   B 2 140 ? 140.945 140.825 134.761 1.00 34.92  ? 140 U   B "C3'" 1 
ATOM 5545 O "O3'" . U   B 2 140 ? 140.277 142.000 134.340 1.00 47.83  ? 140 U   B "O3'" 1 
ATOM 5546 C "C2'" . U   B 2 140 ? 142.378 140.740 134.258 1.00 37.52  ? 140 U   B "C2'" 1 
ATOM 5547 O "O2'" . U   B 2 140 ? 143.008 142.008 134.338 1.00 49.44  ? 140 U   B "O2'" 1 
ATOM 5548 C "C1'" . U   B 2 140 ? 143.023 139.823 135.298 1.00 35.62  ? 140 U   B "C1'" 1 
ATOM 5549 N N1    . U   B 2 140 ? 143.122 138.413 134.859 1.00 35.66  ? 140 U   B N1    1 
ATOM 5550 C C2    . U   B 2 140 ? 144.098 138.068 133.949 1.00 42.86  ? 140 U   B C2    1 
ATOM 5551 O O2    . U   B 2 140 ? 144.875 138.868 133.466 1.00 51.86  ? 140 U   B O2    1 
ATOM 5552 N N3    . U   B 2 140 ? 144.139 136.744 133.603 1.00 38.53  ? 140 U   B N3    1 
ATOM 5553 C C4    . U   B 2 140 ? 143.326 135.743 134.073 1.00 35.77  ? 140 U   B C4    1 
ATOM 5554 O O4    . U   B 2 140 ? 143.486 134.595 133.666 1.00 38.32  ? 140 U   B O4    1 
ATOM 5555 C C5    . U   B 2 140 ? 142.349 136.171 135.017 1.00 35.44  ? 140 U   B C5    1 
ATOM 5556 C C6    . U   B 2 140 ? 142.287 137.456 135.371 1.00 35.23  ? 140 U   B C6    1 
ATOM 5557 P P     . A   B 2 141 ? 138.674 142.063 134.307 1.00 57.92  ? 141 A   B P     1 
ATOM 5558 O OP1   . A   B 2 141 ? 138.240 143.006 135.366 1.00 45.58  ? 141 A   B OP1   1 
ATOM 5559 O OP2   . A   B 2 141 ? 138.149 140.676 134.307 1.00 47.82  ? 141 A   B OP2   1 
ATOM 5560 O "O5'" . A   B 2 141 ? 138.347 142.711 132.894 1.00 52.05  ? 141 A   B "O5'" 1 
ATOM 5561 C "C5'" . A   B 2 141 ? 138.081 144.102 132.769 1.00 50.78  ? 141 A   B "C5'" 1 
ATOM 5562 C "C4'" . A   B 2 141 ? 137.171 144.375 131.601 1.00 50.47  ? 141 A   B "C4'" 1 
ATOM 5563 O "O4'" . A   B 2 141 ? 137.560 143.499 130.512 1.00 49.44  ? 141 A   B "O4'" 1 
ATOM 5564 C "C3'" . A   B 2 141 ? 135.692 144.108 131.859 1.00 53.44  ? 141 A   B "C3'" 1 
ATOM 5565 O "O3'" . A   B 2 141 ? 134.897 145.030 131.118 1.00 55.83  ? 141 A   B "O3'" 1 
ATOM 5566 C "C2'" . A   B 2 141 ? 135.497 142.696 131.315 1.00 50.08  ? 141 A   B "C2'" 1 
ATOM 5567 O "O2'" . A   B 2 141 ? 134.182 142.411 130.891 1.00 54.53  ? 141 A   B "O2'" 1 
ATOM 5568 C "C1'" . A   B 2 141 ? 136.481 142.660 130.149 1.00 46.71  ? 141 A   B "C1'" 1 
ATOM 5569 N N9    . A   B 2 141 ? 137.031 141.326 129.899 1.00 46.91  ? 141 A   B N9    1 
ATOM 5570 C C8    . A   B 2 141 ? 137.523 140.457 130.835 1.00 45.70  ? 141 A   B C8    1 
ATOM 5571 N N7    . A   B 2 141 ? 137.956 139.327 130.336 1.00 44.20  ? 141 A   B N7    1 
ATOM 5572 C C5    . A   B 2 141 ? 137.734 139.462 128.975 1.00 45.45  ? 141 A   B C5    1 
ATOM 5573 C C6    . A   B 2 141 ? 137.975 138.607 127.887 1.00 43.01  ? 141 A   B C6    1 
ATOM 5574 N N6    . A   B 2 141 ? 138.518 137.394 128.002 1.00 43.65  ? 141 A   B N6    1 
ATOM 5575 N N1    . A   B 2 141 ? 137.637 139.044 126.658 1.00 41.98  ? 141 A   B N1    1 
ATOM 5576 C C2    . A   B 2 141 ? 137.092 140.258 126.535 1.00 47.26  ? 141 A   B C2    1 
ATOM 5577 N N3    . A   B 2 141 ? 136.817 141.152 127.479 1.00 46.46  ? 141 A   B N3    1 
ATOM 5578 C C4    . A   B 2 141 ? 137.166 140.688 128.690 1.00 46.27  ? 141 A   B C4    1 
ATOM 5579 P P     . G   B 2 142 ? 133.801 145.940 131.865 1.00 66.75  ? 142 G   B P     1 
ATOM 5580 O OP1   . G   B 2 142 ? 132.464 145.353 131.612 1.00 65.04  ? 142 G   B OP1   1 
ATOM 5581 O OP2   . G   B 2 142 ? 134.059 147.343 131.466 1.00 70.58  ? 142 G   B OP2   1 
ATOM 5582 O "O5'" . G   B 2 142 ? 134.131 145.775 133.418 1.00 65.11  ? 142 G   B "O5'" 1 
ATOM 5583 C "C5'" . G   B 2 142 ? 133.512 146.602 134.407 1.00 69.40  ? 142 G   B "C5'" 1 
ATOM 5584 C "C4'" . G   B 2 142 ? 134.381 147.785 134.751 1.00 70.97  ? 142 G   B "C4'" 1 
ATOM 5585 O "O4'" . G   B 2 142 ? 134.162 148.221 136.128 1.00 67.06  ? 142 G   B "O4'" 1 
ATOM 5586 C "C3'" . G   B 2 142 ? 135.895 147.528 134.637 1.00 71.34  ? 142 G   B "C3'" 1 
ATOM 5587 O "O3'" . G   B 2 142 ? 136.600 148.715 134.207 1.00 81.09  ? 142 G   B "O3'" 1 
ATOM 5588 C "C2'" . G   B 2 142 ? 136.278 147.272 136.096 1.00 66.29  ? 142 G   B "C2'" 1 
ATOM 5589 O "O2'" . G   B 2 142 ? 137.649 147.438 136.389 1.00 67.17  ? 142 G   B "O2'" 1 
ATOM 5590 C "C1'" . G   B 2 142 ? 135.432 148.352 136.718 1.00 66.77  ? 142 G   B "C1'" 1 
ATOM 5591 N N9    . G   B 2 142 ? 135.478 148.742 138.129 1.00 71.68  ? 142 G   B N9    1 
ATOM 5592 C C8    . G   B 2 142 ? 134.438 149.363 138.773 1.00 73.38  ? 142 G   B C8    1 
ATOM 5593 N N7    . G   B 2 142 ? 134.739 149.765 139.970 1.00 77.30  ? 142 G   B N7    1 
ATOM 5594 C C5    . G   B 2 142 ? 136.083 149.458 140.098 1.00 76.06  ? 142 G   B C5    1 
ATOM 5595 C C6    . G   B 2 142 ? 136.946 149.670 141.195 1.00 74.64  ? 142 G   B C6    1 
ATOM 5596 O O6    . G   B 2 142 ? 136.671 150.195 142.274 1.00 76.94  ? 142 G   B O6    1 
ATOM 5597 N N1    . G   B 2 142 ? 138.235 149.229 140.941 1.00 72.41  ? 142 G   B N1    1 
ATOM 5598 C C2    . G   B 2 142 ? 138.639 148.647 139.770 1.00 68.14  ? 142 G   B C2    1 
ATOM 5599 N N2    . G   B 2 142 ? 139.929 148.289 139.728 1.00 67.75  ? 142 G   B N2    1 
ATOM 5600 N N3    . G   B 2 142 ? 137.844 148.437 138.734 1.00 67.72  ? 142 G   B N3    1 
ATOM 5601 C C4    . G   B 2 142 ? 136.580 148.873 138.955 1.00 74.45  ? 142 G   B C4    1 
ATOM 5602 P P     . G   B 2 143 ? 135.935 150.059 133.575 1.00 81.10  ? 143 G   B P     1 
ATOM 5603 O OP1   . G   B 2 143 ? 134.932 149.846 132.503 1.00 80.21  ? 143 G   B OP1   1 
ATOM 5604 O OP2   . G   B 2 143 ? 137.115 150.863 133.187 1.00 79.66  ? 143 G   B OP2   1 
ATOM 5605 O "O5'" . G   B 2 143 ? 135.318 150.869 134.805 1.00 72.57  ? 143 G   B "O5'" 1 
ATOM 5606 C "C5'" . G   B 2 143 ? 135.592 152.256 134.968 1.00 79.60  ? 143 G   B "C5'" 1 
ATOM 5607 C "C4'" . G   B 2 143 ? 135.323 152.748 136.373 1.00 83.10  ? 143 G   B "C4'" 1 
ATOM 5608 O "O4'" . G   B 2 143 ? 135.869 151.818 137.341 1.00 81.09  ? 143 G   B "O4'" 1 
ATOM 5609 C "C3'" . G   B 2 143 ? 135.964 154.083 136.730 1.00 88.69  ? 143 G   B "C3'" 1 
ATOM 5610 O "O3'" . G   B 2 143 ? 135.196 155.192 136.302 1.00 97.98  ? 143 G   B "O3'" 1 
ATOM 5611 C "C2'" . G   B 2 143 ? 136.114 154.003 138.243 1.00 83.68  ? 143 G   B "C2'" 1 
ATOM 5612 O "O2'" . G   B 2 143 ? 134.883 154.305 138.882 1.00 81.10  ? 143 G   B "O2'" 1 
ATOM 5613 C "C1'" . G   B 2 143 ? 136.404 152.519 138.445 1.00 78.77  ? 143 G   B "C1'" 1 
ATOM 5614 N N9    . G   B 2 143 ? 137.844 152.208 138.524 1.00 76.41  ? 143 G   B N9    1 
ATOM 5615 C C8    . G   B 2 143 ? 138.450 151.331 137.665 1.00 79.98  ? 143 G   B C8    1 
ATOM 5616 N N7    . G   B 2 143 ? 139.713 151.157 137.895 1.00 79.22  ? 143 G   B N7    1 
ATOM 5617 C C5    . G   B 2 143 ? 139.964 151.969 138.983 1.00 78.75  ? 143 G   B C5    1 
ATOM 5618 C C6    . G   B 2 143 ? 141.188 152.179 139.651 1.00 83.03  ? 143 G   B C6    1 
ATOM 5619 O O6    . G   B 2 143 ? 142.276 151.653 139.396 1.00 83.02  ? 143 G   B O6    1 
ATOM 5620 N N1    . G   B 2 143 ? 141.050 153.065 140.709 1.00 84.38  ? 143 G   B N1    1 
ATOM 5621 C C2    . G   B 2 143 ? 139.878 153.686 141.065 1.00 83.34  ? 143 G   B C2    1 
ATOM 5622 N N2    . G   B 2 143 ? 139.960 154.518 142.115 1.00 84.26  ? 143 G   B N2    1 
ATOM 5623 N N3    . G   B 2 143 ? 138.719 153.499 140.436 1.00 79.59  ? 143 G   B N3    1 
ATOM 5624 C C4    . G   B 2 143 ? 138.827 152.628 139.405 1.00 77.01  ? 143 G   B C4    1 
ATOM 5625 P P     . A   B 2 144 ? 135.924 156.510 135.748 1.00 109.62 ? 144 A   B P     1 
ATOM 5626 O OP1   . A   B 2 144 ? 134.872 157.472 135.335 1.00 110.86 ? 144 A   B OP1   1 
ATOM 5627 O OP2   . A   B 2 144 ? 136.956 156.081 134.772 1.00 104.85 ? 144 A   B OP2   1 
ATOM 5628 O "O5'" . A   B 2 144 ? 136.668 157.109 137.023 1.00 107.54 ? 144 A   B "O5'" 1 
ATOM 5629 C "C5'" . A   B 2 144 ? 135.941 157.756 138.057 1.00 107.83 ? 144 A   B "C5'" 1 
ATOM 5630 C "C4'" . A   B 2 144 ? 136.860 158.306 139.119 1.00 109.54 ? 144 A   B "C4'" 1 
ATOM 5631 O "O4'" . A   B 2 144 ? 137.532 157.216 139.800 1.00 102.24 ? 144 A   B "O4'" 1 
ATOM 5632 C "C3'" . A   B 2 144 ? 137.998 159.187 138.627 1.00 114.00 ? 144 A   B "C3'" 1 
ATOM 5633 O "O3'" . A   B 2 144 ? 137.596 160.521 138.377 1.00 118.32 ? 144 A   B "O3'" 1 
ATOM 5634 C "C2'" . A   B 2 144 ? 139.023 159.061 139.744 1.00 111.02 ? 144 A   B "C2'" 1 
ATOM 5635 O "O2'" . A   B 2 144 ? 138.668 159.886 140.843 1.00 111.85 ? 144 A   B "O2'" 1 
ATOM 5636 C "C1'" . A   B 2 144 ? 138.840 157.605 140.159 1.00 102.80 ? 144 A   B "C1'" 1 
ATOM 5637 N N9    . A   B 2 144 ? 139.799 156.708 139.490 1.00 98.37  ? 144 A   B N9    1 
ATOM 5638 C C8    . A   B 2 144 ? 139.564 155.863 138.437 1.00 97.25  ? 144 A   B C8    1 
ATOM 5639 N N7    . A   B 2 144 ? 140.617 155.178 138.066 1.00 96.02  ? 144 A   B N7    1 
ATOM 5640 C C5    . A   B 2 144 ? 141.612 155.605 138.932 1.00 96.08  ? 144 A   B C5    1 
ATOM 5641 C C6    . A   B 2 144 ? 142.966 155.257 139.065 1.00 97.50  ? 144 A   B C6    1 
ATOM 5642 N N6    . A   B 2 144 ? 143.576 154.365 138.284 1.00 94.21  ? 144 A   B N6    1 
ATOM 5643 N N1    . A   B 2 144 ? 143.687 155.866 140.032 1.00 102.89 ? 144 A   B N1    1 
ATOM 5644 C C2    . A   B 2 144 ? 143.071 156.761 140.817 1.00 104.27 ? 144 A   B C2    1 
ATOM 5645 N N3    . A   B 2 144 ? 141.803 157.167 140.792 1.00 102.87 ? 144 A   B N3    1 
ATOM 5646 C C4    . A   B 2 144 ? 141.121 156.545 139.817 1.00 98.20  ? 144 A   B C4    1 
ATOM 5647 P P     . C   B 2 145 ? 138.354 161.396 137.263 1.00 129.86 ? 145 C   B P     1 
ATOM 5648 O OP1   . C   B 2 145 ? 137.619 162.678 137.128 1.00 132.05 ? 145 C   B OP1   1 
ATOM 5649 O OP2   . C   B 2 145 ? 138.571 160.540 136.069 1.00 124.24 ? 145 C   B OP2   1 
ATOM 5650 O "O5'" . C   B 2 145 ? 139.774 161.713 137.914 1.00 128.04 ? 145 C   B "O5'" 1 
ATOM 5651 C "C5'" . C   B 2 145 ? 139.887 162.615 139.004 1.00 126.76 ? 145 C   B "C5'" 1 
ATOM 5652 C "C4'" . C   B 2 145 ? 141.246 162.539 139.654 1.00 126.55 ? 145 C   B "C4'" 1 
ATOM 5653 O "O4'" . C   B 2 145 ? 141.578 161.157 139.945 1.00 120.77 ? 145 C   B "O4'" 1 
ATOM 5654 C "C3'" . C   B 2 145 ? 142.418 163.029 138.820 1.00 131.09 ? 145 C   B "C3'" 1 
ATOM 5655 O "O3'" . C   B 2 145 ? 142.546 164.440 138.825 1.00 140.06 ? 145 C   B "O3'" 1 
ATOM 5656 C "C2'" . C   B 2 145 ? 143.601 162.307 139.454 1.00 127.43 ? 145 C   B "C2'" 1 
ATOM 5657 O "O2'" . C   B 2 145 ? 144.007 162.962 140.646 1.00 130.07 ? 145 C   B "O2'" 1 
ATOM 5658 C "C1'" . C   B 2 145 ? 142.973 160.962 139.831 1.00 121.62 ? 145 C   B "C1'" 1 
ATOM 5659 N N1    . C   B 2 145 ? 143.233 159.910 138.818 1.00 114.84 ? 145 C   B N1    1 
ATOM 5660 C C2    . C   B 2 145 ? 144.472 159.258 138.818 1.00 112.91 ? 145 C   B C2    1 
ATOM 5661 O O2    . C   B 2 145 ? 145.335 159.568 139.650 1.00 114.73 ? 145 C   B O2    1 
ATOM 5662 N N3    . C   B 2 145 ? 144.726 158.300 137.901 1.00 110.53 ? 145 C   B N3    1 
ATOM 5663 C C4    . C   B 2 145 ? 143.790 157.972 137.012 1.00 109.11 ? 145 C   B C4    1 
ATOM 5664 N N4    . C   B 2 145 ? 144.083 157.018 136.128 1.00 110.01 ? 145 C   B N4    1 
ATOM 5665 C C5    . C   B 2 145 ? 142.517 158.609 136.985 1.00 108.92 ? 145 C   B C5    1 
ATOM 5666 C C6    . C   B 2 145 ? 142.284 159.560 137.898 1.00 113.04 ? 145 C   B C6    1 
ATOM 5667 P P     . A   B 2 146 ? 143.167 165.205 137.555 1.00 150.67 ? 146 A   B P     1 
ATOM 5668 O OP1   . A   B 2 146 ? 144.201 166.149 138.049 1.00 144.71 ? 146 A   B OP1   1 
ATOM 5669 O OP2   . A   B 2 146 ? 142.042 165.717 136.730 1.00 146.91 ? 146 A   B OP2   1 
ATOM 5670 O "O5'" . A   B 2 146 ? 143.903 164.056 136.733 1.00 136.32 ? 146 A   B "O5'" 1 
ATOM 5671 C "C5'" . A   B 2 146 ? 145.006 164.352 135.892 1.00 132.04 ? 146 A   B "C5'" 1 
ATOM 5672 C "C4'" . A   B 2 146 ? 146.281 163.741 136.417 1.00 127.19 ? 146 A   B "C4'" 1 
ATOM 5673 O "O4'" . A   B 2 146 ? 146.079 162.326 136.675 1.00 122.65 ? 146 A   B "O4'" 1 
ATOM 5674 C "C3'" . A   B 2 146 ? 147.471 163.782 135.471 1.00 123.88 ? 146 A   B "C3'" 1 
ATOM 5675 O "O3'" . A   B 2 146 ? 148.149 165.026 135.489 1.00 120.40 ? 146 A   B "O3'" 1 
ATOM 5676 C "C2'" . A   B 2 146 ? 148.320 162.615 135.951 1.00 119.54 ? 146 A   B "C2'" 1 
ATOM 5677 O "O2'" . A   B 2 146 ? 149.043 162.968 137.121 1.00 115.62 ? 146 A   B "O2'" 1 
ATOM 5678 C "C1'" . A   B 2 146 ? 147.244 161.602 136.338 1.00 120.83 ? 146 A   B "C1'" 1 
ATOM 5679 N N9    . A   B 2 146 ? 146.907 160.686 135.230 1.00 123.13 ? 146 A   B N9    1 
ATOM 5680 C C8    . A   B 2 146 ? 145.655 160.493 134.701 1.00 122.02 ? 146 A   B C8    1 
ATOM 5681 N N7    . A   B 2 146 ? 145.612 159.622 133.726 1.00 122.13 ? 146 A   B N7    1 
ATOM 5682 C C5    . A   B 2 146 ? 146.927 159.205 133.602 1.00 124.25 ? 146 A   B C5    1 
ATOM 5683 C C6    . A   B 2 146 ? 147.543 158.282 132.739 1.00 125.88 ? 146 A   B C6    1 
ATOM 5684 N N6    . A   B 2 146 ? 146.883 157.593 131.806 1.00 123.92 ? 146 A   B N6    1 
ATOM 5685 N N1    . A   B 2 146 ? 148.874 158.085 132.864 1.00 125.90 ? 146 A   B N1    1 
ATOM 5686 C C2    . A   B 2 146 ? 149.538 158.777 133.796 1.00 123.37 ? 146 A   B C2    1 
ATOM 5687 N N3    . A   B 2 146 ? 149.068 159.667 134.668 1.00 122.87 ? 146 A   B N3    1 
ATOM 5688 C C4    . A   B 2 146 ? 147.741 159.846 134.522 1.00 123.78 ? 146 A   B C4    1 
# 
