data_8W1K
# 
_entry.id   8W1K 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.399 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8W1K         pdb_00008w1k 10.2210/pdb8w1k/pdb 
WWPDB D_1000281348 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2024-12-04 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8W1K 
_pdbx_database_status.recvd_initial_deposition_date   2024-02-16 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
loop_
_pdbx_database_related.db_name 
_pdbx_database_related.details 
_pdbx_database_related.db_id 
_pdbx_database_related.content_type 
PDB . 8WIJ unspecified 
PDB . 8VWK unspecified 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              leticia.zanphorlin@lnbr.cnpem.br 
_pdbx_contact_author.name_first         Leticia 
_pdbx_contact_author.name_last          Zanphorlin 
_pdbx_contact_author.name_mi            M 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0001-7283-5726 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Generoso, W.C.'   1 0000-0002-5923-1458 
'Miyamoto, R.Y.'   2 0000-0003-2990-3337 
'Murakami, M.T.'   3 0000-0002-0405-8010 
'Zanphorlin, L.M.' 4 0000-0001-7283-5726 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
'Coordinated conformational changes play a pivotal role in unsaturated fatty acid decarboxylation into renewable olefin' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Generoso, W.C.'    1  0000-0002-5923-1458 
primary 'Alvarenga, A.H.S.' 2  ?                   
primary 'Simoes, I.T.'      3  ?                   
primary 'Miyamoto, R.Y.'    4  0000-0003-2990-3337 
primary 'Mandelli, F.'      5  0000-0003-0891-9241 
primary 'Santos, C.A.'      6  0000-0002-6725-8925 
primary 'Santos, C.R.'      7  0000-0003-0652-4211 
primary 'Colombari, F.M.'   8  0000-0002-5431-1301 
primary 'Morais, M.A.B.'    9  0000-0003-1012-1394 
primary 'Fernandes, R.'     10 ?                   
primary 'Persinoti, G.F.'   11 0000-0002-0975-7283 
primary 'Murakami, M.T.'    12 0000-0002-0405-8010 
primary 'Zanphorlin, L.M.'  13 0000-0001-7283-5726 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Fatty acid decarboxylase'        49393.383 3    ? ? ? ? 
2 non-polymer syn 'PROTOPORPHYRIN IX CONTAINING FE' 616.487   3    ? ? ? ? 
3 non-polymer syn 'OLEIC ACID'                      282.461   3    ? ? ? ? 
4 non-polymer syn 'DI(HYDROXYETHYL)ETHER'           106.120   3    ? ? ? ? 
5 non-polymer syn GLYCEROL                          92.094    6    ? ? ? ? 
6 non-polymer syn 'CHLORIDE ION'                    35.453    2    ? ? ? ? 
7 non-polymer syn 'TRIETHYLENE GLYCOL'              150.173   2    ? ? ? ? 
8 water       nat water                             18.015    1016 ? ? ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MGSSHHHHHHSSGLVPRGSHMMRMTSNQNPRVSGDRTIQFLTDGYLLPSNLRKTAGLEPESMCPVTTKLLGQDATIVRGS
AGIDLFYDEDVMQREGAMPPVIGDALVGKGAVHNLDGEEHKVRKAQMAAMAYEDERVAEFAPLVAEEVERAVAGWEGAQG
NVFEDLSLAFGRAAFRWAGIDLPAENTDELVGRMITLLDNFGTATGTPKAFWQRRQLDNWAEALITDVREGRITARPDCV
LEHMAQLTDASGERVDARTAGIELQNLTRPTVAVGFFASFAAVALAENPQWRTRINESETGREAFAFAQEVRRFYPFVPM
FPAKATKDTEFEGCPIHQGQRVILDFVGTLHSAEEWDNPASFDPERFMAYETQSEAETIKPFIPQGGADVRTGHRCPGEK
IAVTALSAAVEALARPEVRISAEAIDINYSMTEILARPKSGVRVTVASSS
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MGSSHHHHHHSSGLVPRGSHMMRMTSNQNPRVSGDRTIQFLTDGYLLPSNLRKTAGLEPESMCPVTTKLLGQDATIVRGS
AGIDLFYDEDVMQREGAMPPVIGDALVGKGAVHNLDGEEHKVRKAQMAAMAYEDERVAEFAPLVAEEVERAVAGWEGAQG
NVFEDLSLAFGRAAFRWAGIDLPAENTDELVGRMITLLDNFGTATGTPKAFWQRRQLDNWAEALITDVREGRITARPDCV
LEHMAQLTDASGERVDARTAGIELQNLTRPTVAVGFFASFAAVALAENPQWRTRINESETGREAFAFAQEVRRFYPFVPM
FPAKATKDTEFEGCPIHQGQRVILDFVGTLHSAEEWDNPASFDPERFMAYETQSEAETIKPFIPQGGADVRTGHRCPGEK
IAVTALSAAVEALARPEVRISAEAIDINYSMTEILARPKSGVRVTVASSS
;
_entity_poly.pdbx_strand_id                 A,B,C 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 'PROTOPORPHYRIN IX CONTAINING FE' HEM 
3 'OLEIC ACID'                      OLA 
4 'DI(HYDROXYETHYL)ETHER'           PEG 
5 GLYCEROL                          GOL 
6 'CHLORIDE ION'                    CL  
7 'TRIETHYLENE GLYCOL'              PGE 
8 water                             HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   GLY n 
1 3   SER n 
1 4   SER n 
1 5   HIS n 
1 6   HIS n 
1 7   HIS n 
1 8   HIS n 
1 9   HIS n 
1 10  HIS n 
1 11  SER n 
1 12  SER n 
1 13  GLY n 
1 14  LEU n 
1 15  VAL n 
1 16  PRO n 
1 17  ARG n 
1 18  GLY n 
1 19  SER n 
1 20  HIS n 
1 21  MET n 
1 22  MET n 
1 23  ARG n 
1 24  MET n 
1 25  THR n 
1 26  SER n 
1 27  ASN n 
1 28  GLN n 
1 29  ASN n 
1 30  PRO n 
1 31  ARG n 
1 32  VAL n 
1 33  SER n 
1 34  GLY n 
1 35  ASP n 
1 36  ARG n 
1 37  THR n 
1 38  ILE n 
1 39  GLN n 
1 40  PHE n 
1 41  LEU n 
1 42  THR n 
1 43  ASP n 
1 44  GLY n 
1 45  TYR n 
1 46  LEU n 
1 47  LEU n 
1 48  PRO n 
1 49  SER n 
1 50  ASN n 
1 51  LEU n 
1 52  ARG n 
1 53  LYS n 
1 54  THR n 
1 55  ALA n 
1 56  GLY n 
1 57  LEU n 
1 58  GLU n 
1 59  PRO n 
1 60  GLU n 
1 61  SER n 
1 62  MET n 
1 63  CYS n 
1 64  PRO n 
1 65  VAL n 
1 66  THR n 
1 67  THR n 
1 68  LYS n 
1 69  LEU n 
1 70  LEU n 
1 71  GLY n 
1 72  GLN n 
1 73  ASP n 
1 74  ALA n 
1 75  THR n 
1 76  ILE n 
1 77  VAL n 
1 78  ARG n 
1 79  GLY n 
1 80  SER n 
1 81  ALA n 
1 82  GLY n 
1 83  ILE n 
1 84  ASP n 
1 85  LEU n 
1 86  PHE n 
1 87  TYR n 
1 88  ASP n 
1 89  GLU n 
1 90  ASP n 
1 91  VAL n 
1 92  MET n 
1 93  GLN n 
1 94  ARG n 
1 95  GLU n 
1 96  GLY n 
1 97  ALA n 
1 98  MET n 
1 99  PRO n 
1 100 PRO n 
1 101 VAL n 
1 102 ILE n 
1 103 GLY n 
1 104 ASP n 
1 105 ALA n 
1 106 LEU n 
1 107 VAL n 
1 108 GLY n 
1 109 LYS n 
1 110 GLY n 
1 111 ALA n 
1 112 VAL n 
1 113 HIS n 
1 114 ASN n 
1 115 LEU n 
1 116 ASP n 
1 117 GLY n 
1 118 GLU n 
1 119 GLU n 
1 120 HIS n 
1 121 LYS n 
1 122 VAL n 
1 123 ARG n 
1 124 LYS n 
1 125 ALA n 
1 126 GLN n 
1 127 MET n 
1 128 ALA n 
1 129 ALA n 
1 130 MET n 
1 131 ALA n 
1 132 TYR n 
1 133 GLU n 
1 134 ASP n 
1 135 GLU n 
1 136 ARG n 
1 137 VAL n 
1 138 ALA n 
1 139 GLU n 
1 140 PHE n 
1 141 ALA n 
1 142 PRO n 
1 143 LEU n 
1 144 VAL n 
1 145 ALA n 
1 146 GLU n 
1 147 GLU n 
1 148 VAL n 
1 149 GLU n 
1 150 ARG n 
1 151 ALA n 
1 152 VAL n 
1 153 ALA n 
1 154 GLY n 
1 155 TRP n 
1 156 GLU n 
1 157 GLY n 
1 158 ALA n 
1 159 GLN n 
1 160 GLY n 
1 161 ASN n 
1 162 VAL n 
1 163 PHE n 
1 164 GLU n 
1 165 ASP n 
1 166 LEU n 
1 167 SER n 
1 168 LEU n 
1 169 ALA n 
1 170 PHE n 
1 171 GLY n 
1 172 ARG n 
1 173 ALA n 
1 174 ALA n 
1 175 PHE n 
1 176 ARG n 
1 177 TRP n 
1 178 ALA n 
1 179 GLY n 
1 180 ILE n 
1 181 ASP n 
1 182 LEU n 
1 183 PRO n 
1 184 ALA n 
1 185 GLU n 
1 186 ASN n 
1 187 THR n 
1 188 ASP n 
1 189 GLU n 
1 190 LEU n 
1 191 VAL n 
1 192 GLY n 
1 193 ARG n 
1 194 MET n 
1 195 ILE n 
1 196 THR n 
1 197 LEU n 
1 198 LEU n 
1 199 ASP n 
1 200 ASN n 
1 201 PHE n 
1 202 GLY n 
1 203 THR n 
1 204 ALA n 
1 205 THR n 
1 206 GLY n 
1 207 THR n 
1 208 PRO n 
1 209 LYS n 
1 210 ALA n 
1 211 PHE n 
1 212 TRP n 
1 213 GLN n 
1 214 ARG n 
1 215 ARG n 
1 216 GLN n 
1 217 LEU n 
1 218 ASP n 
1 219 ASN n 
1 220 TRP n 
1 221 ALA n 
1 222 GLU n 
1 223 ALA n 
1 224 LEU n 
1 225 ILE n 
1 226 THR n 
1 227 ASP n 
1 228 VAL n 
1 229 ARG n 
1 230 GLU n 
1 231 GLY n 
1 232 ARG n 
1 233 ILE n 
1 234 THR n 
1 235 ALA n 
1 236 ARG n 
1 237 PRO n 
1 238 ASP n 
1 239 CYS n 
1 240 VAL n 
1 241 LEU n 
1 242 GLU n 
1 243 HIS n 
1 244 MET n 
1 245 ALA n 
1 246 GLN n 
1 247 LEU n 
1 248 THR n 
1 249 ASP n 
1 250 ALA n 
1 251 SER n 
1 252 GLY n 
1 253 GLU n 
1 254 ARG n 
1 255 VAL n 
1 256 ASP n 
1 257 ALA n 
1 258 ARG n 
1 259 THR n 
1 260 ALA n 
1 261 GLY n 
1 262 ILE n 
1 263 GLU n 
1 264 LEU n 
1 265 GLN n 
1 266 ASN n 
1 267 LEU n 
1 268 THR n 
1 269 ARG n 
1 270 PRO n 
1 271 THR n 
1 272 VAL n 
1 273 ALA n 
1 274 VAL n 
1 275 GLY n 
1 276 PHE n 
1 277 PHE n 
1 278 ALA n 
1 279 SER n 
1 280 PHE n 
1 281 ALA n 
1 282 ALA n 
1 283 VAL n 
1 284 ALA n 
1 285 LEU n 
1 286 ALA n 
1 287 GLU n 
1 288 ASN n 
1 289 PRO n 
1 290 GLN n 
1 291 TRP n 
1 292 ARG n 
1 293 THR n 
1 294 ARG n 
1 295 ILE n 
1 296 ASN n 
1 297 GLU n 
1 298 SER n 
1 299 GLU n 
1 300 THR n 
1 301 GLY n 
1 302 ARG n 
1 303 GLU n 
1 304 ALA n 
1 305 PHE n 
1 306 ALA n 
1 307 PHE n 
1 308 ALA n 
1 309 GLN n 
1 310 GLU n 
1 311 VAL n 
1 312 ARG n 
1 313 ARG n 
1 314 PHE n 
1 315 TYR n 
1 316 PRO n 
1 317 PHE n 
1 318 VAL n 
1 319 PRO n 
1 320 MET n 
1 321 PHE n 
1 322 PRO n 
1 323 ALA n 
1 324 LYS n 
1 325 ALA n 
1 326 THR n 
1 327 LYS n 
1 328 ASP n 
1 329 THR n 
1 330 GLU n 
1 331 PHE n 
1 332 GLU n 
1 333 GLY n 
1 334 CYS n 
1 335 PRO n 
1 336 ILE n 
1 337 HIS n 
1 338 GLN n 
1 339 GLY n 
1 340 GLN n 
1 341 ARG n 
1 342 VAL n 
1 343 ILE n 
1 344 LEU n 
1 345 ASP n 
1 346 PHE n 
1 347 VAL n 
1 348 GLY n 
1 349 THR n 
1 350 LEU n 
1 351 HIS n 
1 352 SER n 
1 353 ALA n 
1 354 GLU n 
1 355 GLU n 
1 356 TRP n 
1 357 ASP n 
1 358 ASN n 
1 359 PRO n 
1 360 ALA n 
1 361 SER n 
1 362 PHE n 
1 363 ASP n 
1 364 PRO n 
1 365 GLU n 
1 366 ARG n 
1 367 PHE n 
1 368 MET n 
1 369 ALA n 
1 370 TYR n 
1 371 GLU n 
1 372 THR n 
1 373 GLN n 
1 374 SER n 
1 375 GLU n 
1 376 ALA n 
1 377 GLU n 
1 378 THR n 
1 379 ILE n 
1 380 LYS n 
1 381 PRO n 
1 382 PHE n 
1 383 ILE n 
1 384 PRO n 
1 385 GLN n 
1 386 GLY n 
1 387 GLY n 
1 388 ALA n 
1 389 ASP n 
1 390 VAL n 
1 391 ARG n 
1 392 THR n 
1 393 GLY n 
1 394 HIS n 
1 395 ARG n 
1 396 CYS n 
1 397 PRO n 
1 398 GLY n 
1 399 GLU n 
1 400 LYS n 
1 401 ILE n 
1 402 ALA n 
1 403 VAL n 
1 404 THR n 
1 405 ALA n 
1 406 LEU n 
1 407 SER n 
1 408 ALA n 
1 409 ALA n 
1 410 VAL n 
1 411 GLU n 
1 412 ALA n 
1 413 LEU n 
1 414 ALA n 
1 415 ARG n 
1 416 PRO n 
1 417 GLU n 
1 418 VAL n 
1 419 ARG n 
1 420 ILE n 
1 421 SER n 
1 422 ALA n 
1 423 GLU n 
1 424 ALA n 
1 425 ILE n 
1 426 ASP n 
1 427 ILE n 
1 428 ASN n 
1 429 TYR n 
1 430 SER n 
1 431 MET n 
1 432 THR n 
1 433 GLU n 
1 434 ILE n 
1 435 LEU n 
1 436 ALA n 
1 437 ARG n 
1 438 PRO n 
1 439 LYS n 
1 440 SER n 
1 441 GLY n 
1 442 VAL n 
1 443 ARG n 
1 444 VAL n 
1 445 THR n 
1 446 VAL n 
1 447 ALA n 
1 448 SER n 
1 449 SER n 
1 450 SER n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   450 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 HMPREF0298_0515 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Corynebacterium lipophiloflavum' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     161889 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli BL21(DE3)' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     469008 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   'pGTF2 which encodes GroEL, GroES and Tig chaperones' 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                           ?                               'C3 H7 N O2'       89.093  
ARG 'L-peptide linking' y ARGININE                          ?                               'C6 H15 N4 O2 1'   175.209 
ASN 'L-peptide linking' y ASPARAGINE                        ?                               'C4 H8 N2 O3'      132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                   ?                               'C4 H7 N O4'       133.103 
CL  non-polymer         . 'CHLORIDE ION'                    ?                               'Cl -1'            35.453  
CYS 'L-peptide linking' y CYSTEINE                          ?                               'C3 H7 N O2 S'     121.158 
GLN 'L-peptide linking' y GLUTAMINE                         ?                               'C5 H10 N2 O3'     146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                   ?                               'C5 H9 N O4'       147.129 
GLY 'peptide linking'   y GLYCINE                           ?                               'C2 H5 N O2'       75.067  
GOL non-polymer         . GLYCEROL                          'GLYCERIN; PROPANE-1,2,3-TRIOL' 'C3 H8 O3'         92.094  
HEM non-polymer         . 'PROTOPORPHYRIN IX CONTAINING FE' HEME                            'C34 H32 Fe N4 O4' 616.487 
HIS 'L-peptide linking' y HISTIDINE                         ?                               'C6 H10 N3 O2 1'   156.162 
HOH non-polymer         . WATER                             ?                               'H2 O'             18.015  
ILE 'L-peptide linking' y ISOLEUCINE                        ?                               'C6 H13 N O2'      131.173 
LEU 'L-peptide linking' y LEUCINE                           ?                               'C6 H13 N O2'      131.173 
LYS 'L-peptide linking' y LYSINE                            ?                               'C6 H15 N2 O2 1'   147.195 
MET 'L-peptide linking' y METHIONINE                        ?                               'C5 H11 N O2 S'    149.211 
OLA non-polymer         . 'OLEIC ACID'                      ?                               'C18 H34 O2'       282.461 
PEG non-polymer         . 'DI(HYDROXYETHYL)ETHER'           ?                               'C4 H10 O3'        106.120 
PGE non-polymer         . 'TRIETHYLENE GLYCOL'              ?                               'C6 H14 O4'        150.173 
PHE 'L-peptide linking' y PHENYLALANINE                     ?                               'C9 H11 N O2'      165.189 
PRO 'L-peptide linking' y PROLINE                           ?                               'C5 H9 N O2'       115.130 
SER 'L-peptide linking' y SERINE                            ?                               'C3 H7 N O3'       105.093 
THR 'L-peptide linking' y THREONINE                         ?                               'C4 H9 N O3'       119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                        ?                               'C11 H12 N2 O2'    204.225 
TYR 'L-peptide linking' y TYROSINE                          ?                               'C9 H11 N O3'      181.189 
VAL 'L-peptide linking' y VALINE                            ?                               'C5 H11 N O2'      117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   -20 ?   ?   ?   A . n 
A 1 2   GLY 2   -19 ?   ?   ?   A . n 
A 1 3   SER 3   -18 ?   ?   ?   A . n 
A 1 4   SER 4   -17 ?   ?   ?   A . n 
A 1 5   HIS 5   -16 ?   ?   ?   A . n 
A 1 6   HIS 6   -15 ?   ?   ?   A . n 
A 1 7   HIS 7   -14 ?   ?   ?   A . n 
A 1 8   HIS 8   -13 ?   ?   ?   A . n 
A 1 9   HIS 9   -12 ?   ?   ?   A . n 
A 1 10  HIS 10  -11 ?   ?   ?   A . n 
A 1 11  SER 11  -10 ?   ?   ?   A . n 
A 1 12  SER 12  -9  ?   ?   ?   A . n 
A 1 13  GLY 13  -8  ?   ?   ?   A . n 
A 1 14  LEU 14  -7  ?   ?   ?   A . n 
A 1 15  VAL 15  -6  ?   ?   ?   A . n 
A 1 16  PRO 16  -5  ?   ?   ?   A . n 
A 1 17  ARG 17  -4  ?   ?   ?   A . n 
A 1 18  GLY 18  -3  ?   ?   ?   A . n 
A 1 19  SER 19  -2  ?   ?   ?   A . n 
A 1 20  HIS 20  -1  ?   ?   ?   A . n 
A 1 21  MET 21  0   ?   ?   ?   A . n 
A 1 22  MET 22  1   ?   ?   ?   A . n 
A 1 23  ARG 23  2   ?   ?   ?   A . n 
A 1 24  MET 24  3   ?   ?   ?   A . n 
A 1 25  THR 25  4   ?   ?   ?   A . n 
A 1 26  SER 26  5   ?   ?   ?   A . n 
A 1 27  ASN 27  6   ?   ?   ?   A . n 
A 1 28  GLN 28  7   ?   ?   ?   A . n 
A 1 29  ASN 29  8   ?   ?   ?   A . n 
A 1 30  PRO 30  9   9   PRO PRO A . n 
A 1 31  ARG 31  10  10  ARG ARG A . n 
A 1 32  VAL 32  11  11  VAL VAL A . n 
A 1 33  SER 33  12  12  SER SER A . n 
A 1 34  GLY 34  13  13  GLY GLY A . n 
A 1 35  ASP 35  14  14  ASP ASP A . n 
A 1 36  ARG 36  15  15  ARG ARG A . n 
A 1 37  THR 37  16  16  THR THR A . n 
A 1 38  ILE 38  17  17  ILE ILE A . n 
A 1 39  GLN 39  18  18  GLN GLN A . n 
A 1 40  PHE 40  19  19  PHE PHE A . n 
A 1 41  LEU 41  20  20  LEU LEU A . n 
A 1 42  THR 42  21  21  THR THR A . n 
A 1 43  ASP 43  22  22  ASP ASP A . n 
A 1 44  GLY 44  23  23  GLY GLY A . n 
A 1 45  TYR 45  24  24  TYR TYR A . n 
A 1 46  LEU 46  25  25  LEU LEU A . n 
A 1 47  LEU 47  26  26  LEU LEU A . n 
A 1 48  PRO 48  27  27  PRO PRO A . n 
A 1 49  SER 49  28  28  SER SER A . n 
A 1 50  ASN 50  29  29  ASN ASN A . n 
A 1 51  LEU 51  30  30  LEU LEU A . n 
A 1 52  ARG 52  31  31  ARG ARG A . n 
A 1 53  LYS 53  32  32  LYS LYS A . n 
A 1 54  THR 54  33  33  THR THR A . n 
A 1 55  ALA 55  34  34  ALA ALA A . n 
A 1 56  GLY 56  35  35  GLY GLY A . n 
A 1 57  LEU 57  36  36  LEU LEU A . n 
A 1 58  GLU 58  37  37  GLU GLU A . n 
A 1 59  PRO 59  38  38  PRO PRO A . n 
A 1 60  GLU 60  39  39  GLU GLU A . n 
A 1 61  SER 61  40  40  SER SER A . n 
A 1 62  MET 62  41  41  MET MET A . n 
A 1 63  CYS 63  42  42  CYS CYS A . n 
A 1 64  PRO 64  43  43  PRO PRO A . n 
A 1 65  VAL 65  44  44  VAL VAL A . n 
A 1 66  THR 66  45  45  THR THR A . n 
A 1 67  THR 67  46  46  THR THR A . n 
A 1 68  LYS 68  47  47  LYS LYS A . n 
A 1 69  LEU 69  48  48  LEU LEU A . n 
A 1 70  LEU 70  49  49  LEU LEU A . n 
A 1 71  GLY 71  50  50  GLY GLY A . n 
A 1 72  GLN 72  51  51  GLN GLN A . n 
A 1 73  ASP 73  52  52  ASP ASP A . n 
A 1 74  ALA 74  53  53  ALA ALA A . n 
A 1 75  THR 75  54  54  THR THR A . n 
A 1 76  ILE 76  55  55  ILE ILE A . n 
A 1 77  VAL 77  56  56  VAL VAL A . n 
A 1 78  ARG 78  57  57  ARG ARG A . n 
A 1 79  GLY 79  58  58  GLY GLY A . n 
A 1 80  SER 80  59  59  SER SER A . n 
A 1 81  ALA 81  60  60  ALA ALA A . n 
A 1 82  GLY 82  61  61  GLY GLY A . n 
A 1 83  ILE 83  62  62  ILE ILE A . n 
A 1 84  ASP 84  63  63  ASP ASP A . n 
A 1 85  LEU 85  64  64  LEU LEU A . n 
A 1 86  PHE 86  65  65  PHE PHE A . n 
A 1 87  TYR 87  66  66  TYR TYR A . n 
A 1 88  ASP 88  67  67  ASP ASP A . n 
A 1 89  GLU 89  68  68  GLU GLU A . n 
A 1 90  ASP 90  69  69  ASP ASP A . n 
A 1 91  VAL 91  70  70  VAL VAL A . n 
A 1 92  MET 92  71  71  MET MET A . n 
A 1 93  GLN 93  72  72  GLN GLN A . n 
A 1 94  ARG 94  73  73  ARG ARG A . n 
A 1 95  GLU 95  74  74  GLU GLU A . n 
A 1 96  GLY 96  75  75  GLY GLY A . n 
A 1 97  ALA 97  76  76  ALA ALA A . n 
A 1 98  MET 98  77  77  MET MET A . n 
A 1 99  PRO 99  78  78  PRO PRO A . n 
A 1 100 PRO 100 79  79  PRO PRO A . n 
A 1 101 VAL 101 80  80  VAL VAL A . n 
A 1 102 ILE 102 81  81  ILE ILE A . n 
A 1 103 GLY 103 82  82  GLY GLY A . n 
A 1 104 ASP 104 83  83  ASP ASP A . n 
A 1 105 ALA 105 84  84  ALA ALA A . n 
A 1 106 LEU 106 85  85  LEU LEU A . n 
A 1 107 VAL 107 86  86  VAL VAL A . n 
A 1 108 GLY 108 87  87  GLY GLY A . n 
A 1 109 LYS 109 88  88  LYS LYS A . n 
A 1 110 GLY 110 89  89  GLY GLY A . n 
A 1 111 ALA 111 90  90  ALA ALA A . n 
A 1 112 VAL 112 91  91  VAL VAL A . n 
A 1 113 HIS 113 92  92  HIS HIS A . n 
A 1 114 ASN 114 93  93  ASN ASN A . n 
A 1 115 LEU 115 94  94  LEU LEU A . n 
A 1 116 ASP 116 95  95  ASP ASP A . n 
A 1 117 GLY 117 96  96  GLY GLY A . n 
A 1 118 GLU 118 97  97  GLU GLU A . n 
A 1 119 GLU 119 98  98  GLU GLU A . n 
A 1 120 HIS 120 99  99  HIS HIS A . n 
A 1 121 LYS 121 100 100 LYS LYS A . n 
A 1 122 VAL 122 101 101 VAL VAL A . n 
A 1 123 ARG 123 102 102 ARG ARG A . n 
A 1 124 LYS 124 103 103 LYS LYS A . n 
A 1 125 ALA 125 104 104 ALA ALA A . n 
A 1 126 GLN 126 105 105 GLN GLN A . n 
A 1 127 MET 127 106 106 MET MET A . n 
A 1 128 ALA 128 107 107 ALA ALA A . n 
A 1 129 ALA 129 108 108 ALA ALA A . n 
A 1 130 MET 130 109 109 MET MET A . n 
A 1 131 ALA 131 110 110 ALA ALA A . n 
A 1 132 TYR 132 111 111 TYR TYR A . n 
A 1 133 GLU 133 112 112 GLU GLU A . n 
A 1 134 ASP 134 113 113 ASP ASP A . n 
A 1 135 GLU 135 114 114 GLU GLU A . n 
A 1 136 ARG 136 115 115 ARG ARG A . n 
A 1 137 VAL 137 116 116 VAL VAL A . n 
A 1 138 ALA 138 117 117 ALA ALA A . n 
A 1 139 GLU 139 118 118 GLU GLU A . n 
A 1 140 PHE 140 119 119 PHE PHE A . n 
A 1 141 ALA 141 120 120 ALA ALA A . n 
A 1 142 PRO 142 121 121 PRO PRO A . n 
A 1 143 LEU 143 122 122 LEU LEU A . n 
A 1 144 VAL 144 123 123 VAL VAL A . n 
A 1 145 ALA 145 124 124 ALA ALA A . n 
A 1 146 GLU 146 125 125 GLU GLU A . n 
A 1 147 GLU 147 126 126 GLU GLU A . n 
A 1 148 VAL 148 127 127 VAL VAL A . n 
A 1 149 GLU 149 128 128 GLU GLU A . n 
A 1 150 ARG 150 129 129 ARG ARG A . n 
A 1 151 ALA 151 130 130 ALA ALA A . n 
A 1 152 VAL 152 131 131 VAL VAL A . n 
A 1 153 ALA 153 132 132 ALA ALA A . n 
A 1 154 GLY 154 133 133 GLY GLY A . n 
A 1 155 TRP 155 134 134 TRP TRP A . n 
A 1 156 GLU 156 135 135 GLU GLU A . n 
A 1 157 GLY 157 136 136 GLY GLY A . n 
A 1 158 ALA 158 137 137 ALA ALA A . n 
A 1 159 GLN 159 138 138 GLN GLN A . n 
A 1 160 GLY 160 139 139 GLY GLY A . n 
A 1 161 ASN 161 140 140 ASN ASN A . n 
A 1 162 VAL 162 141 141 VAL VAL A . n 
A 1 163 PHE 163 142 142 PHE PHE A . n 
A 1 164 GLU 164 143 143 GLU GLU A . n 
A 1 165 ASP 165 144 144 ASP ASP A . n 
A 1 166 LEU 166 145 145 LEU LEU A . n 
A 1 167 SER 167 146 146 SER SER A . n 
A 1 168 LEU 168 147 147 LEU LEU A . n 
A 1 169 ALA 169 148 148 ALA ALA A . n 
A 1 170 PHE 170 149 149 PHE PHE A . n 
A 1 171 GLY 171 150 150 GLY GLY A . n 
A 1 172 ARG 172 151 151 ARG ARG A . n 
A 1 173 ALA 173 152 152 ALA ALA A . n 
A 1 174 ALA 174 153 153 ALA ALA A . n 
A 1 175 PHE 175 154 154 PHE PHE A . n 
A 1 176 ARG 176 155 155 ARG ARG A . n 
A 1 177 TRP 177 156 156 TRP TRP A . n 
A 1 178 ALA 178 157 157 ALA ALA A . n 
A 1 179 GLY 179 158 158 GLY GLY A . n 
A 1 180 ILE 180 159 159 ILE ILE A . n 
A 1 181 ASP 181 160 160 ASP ASP A . n 
A 1 182 LEU 182 161 161 LEU LEU A . n 
A 1 183 PRO 183 162 162 PRO PRO A . n 
A 1 184 ALA 184 163 163 ALA ALA A . n 
A 1 185 GLU 185 164 164 GLU GLU A . n 
A 1 186 ASN 186 165 165 ASN ASN A . n 
A 1 187 THR 187 166 166 THR THR A . n 
A 1 188 ASP 188 167 167 ASP ASP A . n 
A 1 189 GLU 189 168 168 GLU GLU A . n 
A 1 190 LEU 190 169 169 LEU LEU A . n 
A 1 191 VAL 191 170 170 VAL VAL A . n 
A 1 192 GLY 192 171 171 GLY GLY A . n 
A 1 193 ARG 193 172 172 ARG ARG A . n 
A 1 194 MET 194 173 173 MET MET A . n 
A 1 195 ILE 195 174 174 ILE ILE A . n 
A 1 196 THR 196 175 175 THR THR A . n 
A 1 197 LEU 197 176 176 LEU LEU A . n 
A 1 198 LEU 198 177 177 LEU LEU A . n 
A 1 199 ASP 199 178 178 ASP ASP A . n 
A 1 200 ASN 200 179 179 ASN ASN A . n 
A 1 201 PHE 201 180 180 PHE PHE A . n 
A 1 202 GLY 202 181 181 GLY GLY A . n 
A 1 203 THR 203 182 182 THR THR A . n 
A 1 204 ALA 204 183 183 ALA ALA A . n 
A 1 205 THR 205 184 184 THR THR A . n 
A 1 206 GLY 206 185 185 GLY GLY A . n 
A 1 207 THR 207 186 186 THR THR A . n 
A 1 208 PRO 208 187 187 PRO PRO A . n 
A 1 209 LYS 209 188 188 LYS LYS A . n 
A 1 210 ALA 210 189 189 ALA ALA A . n 
A 1 211 PHE 211 190 190 PHE PHE A . n 
A 1 212 TRP 212 191 191 TRP TRP A . n 
A 1 213 GLN 213 192 192 GLN GLN A . n 
A 1 214 ARG 214 193 193 ARG ARG A . n 
A 1 215 ARG 215 194 194 ARG ARG A . n 
A 1 216 GLN 216 195 195 GLN GLN A . n 
A 1 217 LEU 217 196 196 LEU LEU A . n 
A 1 218 ASP 218 197 197 ASP ASP A . n 
A 1 219 ASN 219 198 198 ASN ASN A . n 
A 1 220 TRP 220 199 199 TRP TRP A . n 
A 1 221 ALA 221 200 200 ALA ALA A . n 
A 1 222 GLU 222 201 201 GLU GLU A . n 
A 1 223 ALA 223 202 202 ALA ALA A . n 
A 1 224 LEU 224 203 203 LEU LEU A . n 
A 1 225 ILE 225 204 204 ILE ILE A . n 
A 1 226 THR 226 205 205 THR THR A . n 
A 1 227 ASP 227 206 206 ASP ASP A . n 
A 1 228 VAL 228 207 207 VAL VAL A . n 
A 1 229 ARG 229 208 208 ARG ARG A . n 
A 1 230 GLU 230 209 209 GLU GLU A . n 
A 1 231 GLY 231 210 210 GLY GLY A . n 
A 1 232 ARG 232 211 211 ARG ARG A . n 
A 1 233 ILE 233 212 212 ILE ILE A . n 
A 1 234 THR 234 213 213 THR THR A . n 
A 1 235 ALA 235 214 214 ALA ALA A . n 
A 1 236 ARG 236 215 215 ARG ARG A . n 
A 1 237 PRO 237 216 216 PRO PRO A . n 
A 1 238 ASP 238 217 217 ASP ASP A . n 
A 1 239 CYS 239 218 218 CYS CYS A . n 
A 1 240 VAL 240 219 219 VAL VAL A . n 
A 1 241 LEU 241 220 220 LEU LEU A . n 
A 1 242 GLU 242 221 221 GLU GLU A . n 
A 1 243 HIS 243 222 222 HIS HIS A . n 
A 1 244 MET 244 223 223 MET MET A . n 
A 1 245 ALA 245 224 224 ALA ALA A . n 
A 1 246 GLN 246 225 225 GLN GLN A . n 
A 1 247 LEU 247 226 226 LEU LEU A . n 
A 1 248 THR 248 227 227 THR THR A . n 
A 1 249 ASP 249 228 228 ASP ASP A . n 
A 1 250 ALA 250 229 229 ALA ALA A . n 
A 1 251 SER 251 230 230 SER SER A . n 
A 1 252 GLY 252 231 231 GLY GLY A . n 
A 1 253 GLU 253 232 232 GLU GLU A . n 
A 1 254 ARG 254 233 233 ARG ARG A . n 
A 1 255 VAL 255 234 234 VAL VAL A . n 
A 1 256 ASP 256 235 235 ASP ASP A . n 
A 1 257 ALA 257 236 236 ALA ALA A . n 
A 1 258 ARG 258 237 237 ARG ARG A . n 
A 1 259 THR 259 238 238 THR THR A . n 
A 1 260 ALA 260 239 239 ALA ALA A . n 
A 1 261 GLY 261 240 240 GLY GLY A . n 
A 1 262 ILE 262 241 241 ILE ILE A . n 
A 1 263 GLU 263 242 242 GLU GLU A . n 
A 1 264 LEU 264 243 243 LEU LEU A . n 
A 1 265 GLN 265 244 244 GLN GLN A . n 
A 1 266 ASN 266 245 245 ASN ASN A . n 
A 1 267 LEU 267 246 246 LEU LEU A . n 
A 1 268 THR 268 247 247 THR THR A . n 
A 1 269 ARG 269 248 248 ARG ARG A . n 
A 1 270 PRO 270 249 249 PRO PRO A . n 
A 1 271 THR 271 250 250 THR THR A . n 
A 1 272 VAL 272 251 251 VAL VAL A . n 
A 1 273 ALA 273 252 252 ALA ALA A . n 
A 1 274 VAL 274 253 253 VAL VAL A . n 
A 1 275 GLY 275 254 254 GLY GLY A . n 
A 1 276 PHE 276 255 255 PHE PHE A . n 
A 1 277 PHE 277 256 256 PHE PHE A . n 
A 1 278 ALA 278 257 257 ALA ALA A . n 
A 1 279 SER 279 258 258 SER SER A . n 
A 1 280 PHE 280 259 259 PHE PHE A . n 
A 1 281 ALA 281 260 260 ALA ALA A . n 
A 1 282 ALA 282 261 261 ALA ALA A . n 
A 1 283 VAL 283 262 262 VAL VAL A . n 
A 1 284 ALA 284 263 263 ALA ALA A . n 
A 1 285 LEU 285 264 264 LEU LEU A . n 
A 1 286 ALA 286 265 265 ALA ALA A . n 
A 1 287 GLU 287 266 266 GLU GLU A . n 
A 1 288 ASN 288 267 267 ASN ASN A . n 
A 1 289 PRO 289 268 268 PRO PRO A . n 
A 1 290 GLN 290 269 269 GLN GLN A . n 
A 1 291 TRP 291 270 270 TRP TRP A . n 
A 1 292 ARG 292 271 271 ARG ARG A . n 
A 1 293 THR 293 272 272 THR THR A . n 
A 1 294 ARG 294 273 273 ARG ARG A . n 
A 1 295 ILE 295 274 274 ILE ILE A . n 
A 1 296 ASN 296 275 275 ASN ASN A . n 
A 1 297 GLU 297 276 276 GLU GLU A . n 
A 1 298 SER 298 277 277 SER SER A . n 
A 1 299 GLU 299 278 278 GLU GLU A . n 
A 1 300 THR 300 279 279 THR THR A . n 
A 1 301 GLY 301 280 280 GLY GLY A . n 
A 1 302 ARG 302 281 281 ARG ARG A . n 
A 1 303 GLU 303 282 282 GLU GLU A . n 
A 1 304 ALA 304 283 283 ALA ALA A . n 
A 1 305 PHE 305 284 284 PHE PHE A . n 
A 1 306 ALA 306 285 285 ALA ALA A . n 
A 1 307 PHE 307 286 286 PHE PHE A . n 
A 1 308 ALA 308 287 287 ALA ALA A . n 
A 1 309 GLN 309 288 288 GLN GLN A . n 
A 1 310 GLU 310 289 289 GLU GLU A . n 
A 1 311 VAL 311 290 290 VAL VAL A . n 
A 1 312 ARG 312 291 291 ARG ARG A . n 
A 1 313 ARG 313 292 292 ARG ARG A . n 
A 1 314 PHE 314 293 293 PHE PHE A . n 
A 1 315 TYR 315 294 294 TYR TYR A . n 
A 1 316 PRO 316 295 295 PRO PRO A . n 
A 1 317 PHE 317 296 296 PHE PHE A . n 
A 1 318 VAL 318 297 297 VAL VAL A . n 
A 1 319 PRO 319 298 298 PRO PRO A . n 
A 1 320 MET 320 299 299 MET MET A . n 
A 1 321 PHE 321 300 300 PHE PHE A . n 
A 1 322 PRO 322 301 301 PRO PRO A . n 
A 1 323 ALA 323 302 302 ALA ALA A . n 
A 1 324 LYS 324 303 303 LYS LYS A . n 
A 1 325 ALA 325 304 304 ALA ALA A . n 
A 1 326 THR 326 305 305 THR THR A . n 
A 1 327 LYS 327 306 306 LYS LYS A . n 
A 1 328 ASP 328 307 307 ASP ASP A . n 
A 1 329 THR 329 308 308 THR THR A . n 
A 1 330 GLU 330 309 309 GLU GLU A . n 
A 1 331 PHE 331 310 310 PHE PHE A . n 
A 1 332 GLU 332 311 311 GLU GLU A . n 
A 1 333 GLY 333 312 312 GLY GLY A . n 
A 1 334 CYS 334 313 313 CYS CYS A . n 
A 1 335 PRO 335 314 314 PRO PRO A . n 
A 1 336 ILE 336 315 315 ILE ILE A . n 
A 1 337 HIS 337 316 316 HIS HIS A . n 
A 1 338 GLN 338 317 317 GLN GLN A . n 
A 1 339 GLY 339 318 318 GLY GLY A . n 
A 1 340 GLN 340 319 319 GLN GLN A . n 
A 1 341 ARG 341 320 320 ARG ARG A . n 
A 1 342 VAL 342 321 321 VAL VAL A . n 
A 1 343 ILE 343 322 322 ILE ILE A . n 
A 1 344 LEU 344 323 323 LEU LEU A . n 
A 1 345 ASP 345 324 324 ASP ASP A . n 
A 1 346 PHE 346 325 325 PHE PHE A . n 
A 1 347 VAL 347 326 326 VAL VAL A . n 
A 1 348 GLY 348 327 327 GLY GLY A . n 
A 1 349 THR 349 328 328 THR THR A . n 
A 1 350 LEU 350 329 329 LEU LEU A . n 
A 1 351 HIS 351 330 330 HIS HIS A . n 
A 1 352 SER 352 331 331 SER SER A . n 
A 1 353 ALA 353 332 332 ALA ALA A . n 
A 1 354 GLU 354 333 333 GLU GLU A . n 
A 1 355 GLU 355 334 334 GLU GLU A . n 
A 1 356 TRP 356 335 335 TRP TRP A . n 
A 1 357 ASP 357 336 336 ASP ASP A . n 
A 1 358 ASN 358 337 337 ASN ASN A . n 
A 1 359 PRO 359 338 338 PRO PRO A . n 
A 1 360 ALA 360 339 339 ALA ALA A . n 
A 1 361 SER 361 340 340 SER SER A . n 
A 1 362 PHE 362 341 341 PHE PHE A . n 
A 1 363 ASP 363 342 342 ASP ASP A . n 
A 1 364 PRO 364 343 343 PRO PRO A . n 
A 1 365 GLU 365 344 344 GLU GLU A . n 
A 1 366 ARG 366 345 345 ARG ARG A . n 
A 1 367 PHE 367 346 346 PHE PHE A . n 
A 1 368 MET 368 347 347 MET MET A . n 
A 1 369 ALA 369 348 348 ALA ALA A . n 
A 1 370 TYR 370 349 349 TYR TYR A . n 
A 1 371 GLU 371 350 350 GLU GLU A . n 
A 1 372 THR 372 351 351 THR THR A . n 
A 1 373 GLN 373 352 352 GLN GLN A . n 
A 1 374 SER 374 353 353 SER SER A . n 
A 1 375 GLU 375 354 354 GLU GLU A . n 
A 1 376 ALA 376 355 355 ALA ALA A . n 
A 1 377 GLU 377 356 356 GLU GLU A . n 
A 1 378 THR 378 357 357 THR THR A . n 
A 1 379 ILE 379 358 358 ILE ILE A . n 
A 1 380 LYS 380 359 359 LYS LYS A . n 
A 1 381 PRO 381 360 360 PRO PRO A . n 
A 1 382 PHE 382 361 361 PHE PHE A . n 
A 1 383 ILE 383 362 362 ILE ILE A . n 
A 1 384 PRO 384 363 363 PRO PRO A . n 
A 1 385 GLN 385 364 364 GLN GLN A . n 
A 1 386 GLY 386 365 365 GLY GLY A . n 
A 1 387 GLY 387 366 366 GLY GLY A . n 
A 1 388 ALA 388 367 367 ALA ALA A . n 
A 1 389 ASP 389 368 368 ASP ASP A . n 
A 1 390 VAL 390 369 369 VAL VAL A . n 
A 1 391 ARG 391 370 370 ARG ARG A . n 
A 1 392 THR 392 371 371 THR THR A . n 
A 1 393 GLY 393 372 372 GLY GLY A . n 
A 1 394 HIS 394 373 373 HIS HIS A . n 
A 1 395 ARG 395 374 374 ARG ARG A . n 
A 1 396 CYS 396 375 375 CYS CYS A . n 
A 1 397 PRO 397 376 376 PRO PRO A . n 
A 1 398 GLY 398 377 377 GLY GLY A . n 
A 1 399 GLU 399 378 378 GLU GLU A . n 
A 1 400 LYS 400 379 379 LYS LYS A . n 
A 1 401 ILE 401 380 380 ILE ILE A . n 
A 1 402 ALA 402 381 381 ALA ALA A . n 
A 1 403 VAL 403 382 382 VAL VAL A . n 
A 1 404 THR 404 383 383 THR THR A . n 
A 1 405 ALA 405 384 384 ALA ALA A . n 
A 1 406 LEU 406 385 385 LEU LEU A . n 
A 1 407 SER 407 386 386 SER SER A . n 
A 1 408 ALA 408 387 387 ALA ALA A . n 
A 1 409 ALA 409 388 388 ALA ALA A . n 
A 1 410 VAL 410 389 389 VAL VAL A . n 
A 1 411 GLU 411 390 390 GLU GLU A . n 
A 1 412 ALA 412 391 391 ALA ALA A . n 
A 1 413 LEU 413 392 392 LEU LEU A . n 
A 1 414 ALA 414 393 393 ALA ALA A . n 
A 1 415 ARG 415 394 394 ARG ARG A . n 
A 1 416 PRO 416 395 395 PRO PRO A . n 
A 1 417 GLU 417 396 396 GLU GLU A . n 
A 1 418 VAL 418 397 397 VAL VAL A . n 
A 1 419 ARG 419 398 398 ARG ARG A . n 
A 1 420 ILE 420 399 399 ILE ILE A . n 
A 1 421 SER 421 400 400 SER SER A . n 
A 1 422 ALA 422 401 401 ALA ALA A . n 
A 1 423 GLU 423 402 402 GLU GLU A . n 
A 1 424 ALA 424 403 403 ALA ALA A . n 
A 1 425 ILE 425 404 404 ILE ILE A . n 
A 1 426 ASP 426 405 405 ASP ASP A . n 
A 1 427 ILE 427 406 406 ILE ILE A . n 
A 1 428 ASN 428 407 407 ASN ASN A . n 
A 1 429 TYR 429 408 408 TYR TYR A . n 
A 1 430 SER 430 409 409 SER SER A . n 
A 1 431 MET 431 410 410 MET MET A . n 
A 1 432 THR 432 411 411 THR THR A . n 
A 1 433 GLU 433 412 412 GLU GLU A . n 
A 1 434 ILE 434 413 413 ILE ILE A . n 
A 1 435 LEU 435 414 414 LEU LEU A . n 
A 1 436 ALA 436 415 415 ALA ALA A . n 
A 1 437 ARG 437 416 416 ARG ARG A . n 
A 1 438 PRO 438 417 417 PRO PRO A . n 
A 1 439 LYS 439 418 418 LYS LYS A . n 
A 1 440 SER 440 419 419 SER SER A . n 
A 1 441 GLY 441 420 420 GLY GLY A . n 
A 1 442 VAL 442 421 421 VAL VAL A . n 
A 1 443 ARG 443 422 422 ARG ARG A . n 
A 1 444 VAL 444 423 423 VAL VAL A . n 
A 1 445 THR 445 424 424 THR THR A . n 
A 1 446 VAL 446 425 425 VAL VAL A . n 
A 1 447 ALA 447 426 426 ALA ALA A . n 
A 1 448 SER 448 427 427 SER SER A . n 
A 1 449 SER 449 428 428 SER SER A . n 
A 1 450 SER 450 429 ?   ?   ?   A . n 
B 1 1   MET 1   -20 ?   ?   ?   B . n 
B 1 2   GLY 2   -19 ?   ?   ?   B . n 
B 1 3   SER 3   -18 ?   ?   ?   B . n 
B 1 4   SER 4   -17 ?   ?   ?   B . n 
B 1 5   HIS 5   -16 ?   ?   ?   B . n 
B 1 6   HIS 6   -15 ?   ?   ?   B . n 
B 1 7   HIS 7   -14 ?   ?   ?   B . n 
B 1 8   HIS 8   -13 ?   ?   ?   B . n 
B 1 9   HIS 9   -12 ?   ?   ?   B . n 
B 1 10  HIS 10  -11 ?   ?   ?   B . n 
B 1 11  SER 11  -10 ?   ?   ?   B . n 
B 1 12  SER 12  -9  ?   ?   ?   B . n 
B 1 13  GLY 13  -8  ?   ?   ?   B . n 
B 1 14  LEU 14  -7  ?   ?   ?   B . n 
B 1 15  VAL 15  -6  ?   ?   ?   B . n 
B 1 16  PRO 16  -5  ?   ?   ?   B . n 
B 1 17  ARG 17  -4  ?   ?   ?   B . n 
B 1 18  GLY 18  -3  ?   ?   ?   B . n 
B 1 19  SER 19  -2  ?   ?   ?   B . n 
B 1 20  HIS 20  -1  ?   ?   ?   B . n 
B 1 21  MET 21  0   ?   ?   ?   B . n 
B 1 22  MET 22  1   ?   ?   ?   B . n 
B 1 23  ARG 23  2   ?   ?   ?   B . n 
B 1 24  MET 24  3   ?   ?   ?   B . n 
B 1 25  THR 25  4   ?   ?   ?   B . n 
B 1 26  SER 26  5   ?   ?   ?   B . n 
B 1 27  ASN 27  6   ?   ?   ?   B . n 
B 1 28  GLN 28  7   ?   ?   ?   B . n 
B 1 29  ASN 29  8   8   ASN ASN B . n 
B 1 30  PRO 30  9   9   PRO PRO B . n 
B 1 31  ARG 31  10  10  ARG ARG B . n 
B 1 32  VAL 32  11  11  VAL VAL B . n 
B 1 33  SER 33  12  12  SER SER B . n 
B 1 34  GLY 34  13  13  GLY GLY B . n 
B 1 35  ASP 35  14  14  ASP ASP B . n 
B 1 36  ARG 36  15  15  ARG ARG B . n 
B 1 37  THR 37  16  16  THR THR B . n 
B 1 38  ILE 38  17  17  ILE ILE B . n 
B 1 39  GLN 39  18  18  GLN GLN B . n 
B 1 40  PHE 40  19  19  PHE PHE B . n 
B 1 41  LEU 41  20  20  LEU LEU B . n 
B 1 42  THR 42  21  21  THR THR B . n 
B 1 43  ASP 43  22  22  ASP ASP B . n 
B 1 44  GLY 44  23  23  GLY GLY B . n 
B 1 45  TYR 45  24  24  TYR TYR B . n 
B 1 46  LEU 46  25  25  LEU LEU B . n 
B 1 47  LEU 47  26  26  LEU LEU B . n 
B 1 48  PRO 48  27  27  PRO PRO B . n 
B 1 49  SER 49  28  28  SER SER B . n 
B 1 50  ASN 50  29  29  ASN ASN B . n 
B 1 51  LEU 51  30  30  LEU LEU B . n 
B 1 52  ARG 52  31  31  ARG ARG B . n 
B 1 53  LYS 53  32  32  LYS LYS B . n 
B 1 54  THR 54  33  33  THR THR B . n 
B 1 55  ALA 55  34  34  ALA ALA B . n 
B 1 56  GLY 56  35  35  GLY GLY B . n 
B 1 57  LEU 57  36  36  LEU LEU B . n 
B 1 58  GLU 58  37  37  GLU GLU B . n 
B 1 59  PRO 59  38  38  PRO PRO B . n 
B 1 60  GLU 60  39  39  GLU GLU B . n 
B 1 61  SER 61  40  40  SER SER B . n 
B 1 62  MET 62  41  41  MET MET B . n 
B 1 63  CYS 63  42  42  CYS CYS B . n 
B 1 64  PRO 64  43  43  PRO PRO B . n 
B 1 65  VAL 65  44  44  VAL VAL B . n 
B 1 66  THR 66  45  45  THR THR B . n 
B 1 67  THR 67  46  46  THR THR B . n 
B 1 68  LYS 68  47  47  LYS LYS B . n 
B 1 69  LEU 69  48  48  LEU LEU B . n 
B 1 70  LEU 70  49  49  LEU LEU B . n 
B 1 71  GLY 71  50  50  GLY GLY B . n 
B 1 72  GLN 72  51  51  GLN GLN B . n 
B 1 73  ASP 73  52  52  ASP ASP B . n 
B 1 74  ALA 74  53  53  ALA ALA B . n 
B 1 75  THR 75  54  54  THR THR B . n 
B 1 76  ILE 76  55  55  ILE ILE B . n 
B 1 77  VAL 77  56  56  VAL VAL B . n 
B 1 78  ARG 78  57  57  ARG ARG B . n 
B 1 79  GLY 79  58  58  GLY GLY B . n 
B 1 80  SER 80  59  59  SER SER B . n 
B 1 81  ALA 81  60  60  ALA ALA B . n 
B 1 82  GLY 82  61  61  GLY GLY B . n 
B 1 83  ILE 83  62  62  ILE ILE B . n 
B 1 84  ASP 84  63  63  ASP ASP B . n 
B 1 85  LEU 85  64  64  LEU LEU B . n 
B 1 86  PHE 86  65  65  PHE PHE B . n 
B 1 87  TYR 87  66  66  TYR TYR B . n 
B 1 88  ASP 88  67  67  ASP ASP B . n 
B 1 89  GLU 89  68  68  GLU GLU B . n 
B 1 90  ASP 90  69  69  ASP ASP B . n 
B 1 91  VAL 91  70  70  VAL VAL B . n 
B 1 92  MET 92  71  71  MET MET B . n 
B 1 93  GLN 93  72  72  GLN GLN B . n 
B 1 94  ARG 94  73  73  ARG ARG B . n 
B 1 95  GLU 95  74  74  GLU GLU B . n 
B 1 96  GLY 96  75  75  GLY GLY B . n 
B 1 97  ALA 97  76  76  ALA ALA B . n 
B 1 98  MET 98  77  77  MET MET B . n 
B 1 99  PRO 99  78  78  PRO PRO B . n 
B 1 100 PRO 100 79  79  PRO PRO B . n 
B 1 101 VAL 101 80  80  VAL VAL B . n 
B 1 102 ILE 102 81  81  ILE ILE B . n 
B 1 103 GLY 103 82  82  GLY GLY B . n 
B 1 104 ASP 104 83  83  ASP ASP B . n 
B 1 105 ALA 105 84  84  ALA ALA B . n 
B 1 106 LEU 106 85  85  LEU LEU B . n 
B 1 107 VAL 107 86  86  VAL VAL B . n 
B 1 108 GLY 108 87  87  GLY GLY B . n 
B 1 109 LYS 109 88  88  LYS LYS B . n 
B 1 110 GLY 110 89  89  GLY GLY B . n 
B 1 111 ALA 111 90  90  ALA ALA B . n 
B 1 112 VAL 112 91  91  VAL VAL B . n 
B 1 113 HIS 113 92  92  HIS HIS B . n 
B 1 114 ASN 114 93  93  ASN ASN B . n 
B 1 115 LEU 115 94  94  LEU LEU B . n 
B 1 116 ASP 116 95  95  ASP ASP B . n 
B 1 117 GLY 117 96  96  GLY GLY B . n 
B 1 118 GLU 118 97  97  GLU GLU B . n 
B 1 119 GLU 119 98  98  GLU GLU B . n 
B 1 120 HIS 120 99  99  HIS HIS B . n 
B 1 121 LYS 121 100 100 LYS LYS B . n 
B 1 122 VAL 122 101 101 VAL VAL B . n 
B 1 123 ARG 123 102 102 ARG ARG B . n 
B 1 124 LYS 124 103 103 LYS LYS B . n 
B 1 125 ALA 125 104 104 ALA ALA B . n 
B 1 126 GLN 126 105 105 GLN GLN B . n 
B 1 127 MET 127 106 106 MET MET B . n 
B 1 128 ALA 128 107 107 ALA ALA B . n 
B 1 129 ALA 129 108 108 ALA ALA B . n 
B 1 130 MET 130 109 109 MET MET B . n 
B 1 131 ALA 131 110 110 ALA ALA B . n 
B 1 132 TYR 132 111 111 TYR TYR B . n 
B 1 133 GLU 133 112 112 GLU GLU B . n 
B 1 134 ASP 134 113 113 ASP ASP B . n 
B 1 135 GLU 135 114 114 GLU GLU B . n 
B 1 136 ARG 136 115 115 ARG ARG B . n 
B 1 137 VAL 137 116 116 VAL VAL B . n 
B 1 138 ALA 138 117 117 ALA ALA B . n 
B 1 139 GLU 139 118 118 GLU GLU B . n 
B 1 140 PHE 140 119 119 PHE PHE B . n 
B 1 141 ALA 141 120 120 ALA ALA B . n 
B 1 142 PRO 142 121 121 PRO PRO B . n 
B 1 143 LEU 143 122 122 LEU LEU B . n 
B 1 144 VAL 144 123 123 VAL VAL B . n 
B 1 145 ALA 145 124 124 ALA ALA B . n 
B 1 146 GLU 146 125 125 GLU GLU B . n 
B 1 147 GLU 147 126 126 GLU GLU B . n 
B 1 148 VAL 148 127 127 VAL VAL B . n 
B 1 149 GLU 149 128 128 GLU GLU B . n 
B 1 150 ARG 150 129 129 ARG ARG B . n 
B 1 151 ALA 151 130 130 ALA ALA B . n 
B 1 152 VAL 152 131 131 VAL VAL B . n 
B 1 153 ALA 153 132 132 ALA ALA B . n 
B 1 154 GLY 154 133 133 GLY GLY B . n 
B 1 155 TRP 155 134 134 TRP TRP B . n 
B 1 156 GLU 156 135 135 GLU GLU B . n 
B 1 157 GLY 157 136 136 GLY GLY B . n 
B 1 158 ALA 158 137 137 ALA ALA B . n 
B 1 159 GLN 159 138 138 GLN GLN B . n 
B 1 160 GLY 160 139 139 GLY GLY B . n 
B 1 161 ASN 161 140 140 ASN ASN B . n 
B 1 162 VAL 162 141 141 VAL VAL B . n 
B 1 163 PHE 163 142 142 PHE PHE B . n 
B 1 164 GLU 164 143 143 GLU GLU B . n 
B 1 165 ASP 165 144 144 ASP ASP B . n 
B 1 166 LEU 166 145 145 LEU LEU B . n 
B 1 167 SER 167 146 146 SER SER B . n 
B 1 168 LEU 168 147 147 LEU LEU B . n 
B 1 169 ALA 169 148 148 ALA ALA B . n 
B 1 170 PHE 170 149 149 PHE PHE B . n 
B 1 171 GLY 171 150 150 GLY GLY B . n 
B 1 172 ARG 172 151 151 ARG ARG B . n 
B 1 173 ALA 173 152 152 ALA ALA B . n 
B 1 174 ALA 174 153 153 ALA ALA B . n 
B 1 175 PHE 175 154 154 PHE PHE B . n 
B 1 176 ARG 176 155 155 ARG ARG B . n 
B 1 177 TRP 177 156 156 TRP TRP B . n 
B 1 178 ALA 178 157 157 ALA ALA B . n 
B 1 179 GLY 179 158 158 GLY GLY B . n 
B 1 180 ILE 180 159 159 ILE ILE B . n 
B 1 181 ASP 181 160 160 ASP ASP B . n 
B 1 182 LEU 182 161 161 LEU LEU B . n 
B 1 183 PRO 183 162 162 PRO PRO B . n 
B 1 184 ALA 184 163 163 ALA ALA B . n 
B 1 185 GLU 185 164 164 GLU GLU B . n 
B 1 186 ASN 186 165 165 ASN ASN B . n 
B 1 187 THR 187 166 166 THR THR B . n 
B 1 188 ASP 188 167 167 ASP ASP B . n 
B 1 189 GLU 189 168 168 GLU GLU B . n 
B 1 190 LEU 190 169 169 LEU LEU B . n 
B 1 191 VAL 191 170 170 VAL VAL B . n 
B 1 192 GLY 192 171 171 GLY GLY B . n 
B 1 193 ARG 193 172 172 ARG ARG B . n 
B 1 194 MET 194 173 173 MET MET B . n 
B 1 195 ILE 195 174 174 ILE ILE B . n 
B 1 196 THR 196 175 175 THR THR B . n 
B 1 197 LEU 197 176 176 LEU LEU B . n 
B 1 198 LEU 198 177 177 LEU LEU B . n 
B 1 199 ASP 199 178 178 ASP ASP B . n 
B 1 200 ASN 200 179 179 ASN ASN B . n 
B 1 201 PHE 201 180 180 PHE PHE B . n 
B 1 202 GLY 202 181 181 GLY GLY B . n 
B 1 203 THR 203 182 182 THR THR B . n 
B 1 204 ALA 204 183 183 ALA ALA B . n 
B 1 205 THR 205 184 184 THR THR B . n 
B 1 206 GLY 206 185 185 GLY GLY B . n 
B 1 207 THR 207 186 186 THR THR B . n 
B 1 208 PRO 208 187 187 PRO PRO B . n 
B 1 209 LYS 209 188 188 LYS LYS B . n 
B 1 210 ALA 210 189 189 ALA ALA B . n 
B 1 211 PHE 211 190 190 PHE PHE B . n 
B 1 212 TRP 212 191 191 TRP TRP B . n 
B 1 213 GLN 213 192 192 GLN GLN B . n 
B 1 214 ARG 214 193 193 ARG ARG B . n 
B 1 215 ARG 215 194 194 ARG ARG B . n 
B 1 216 GLN 216 195 195 GLN GLN B . n 
B 1 217 LEU 217 196 196 LEU LEU B . n 
B 1 218 ASP 218 197 197 ASP ASP B . n 
B 1 219 ASN 219 198 198 ASN ASN B . n 
B 1 220 TRP 220 199 199 TRP TRP B . n 
B 1 221 ALA 221 200 200 ALA ALA B . n 
B 1 222 GLU 222 201 201 GLU GLU B . n 
B 1 223 ALA 223 202 202 ALA ALA B . n 
B 1 224 LEU 224 203 203 LEU LEU B . n 
B 1 225 ILE 225 204 204 ILE ILE B . n 
B 1 226 THR 226 205 205 THR THR B . n 
B 1 227 ASP 227 206 206 ASP ASP B . n 
B 1 228 VAL 228 207 207 VAL VAL B . n 
B 1 229 ARG 229 208 208 ARG ARG B . n 
B 1 230 GLU 230 209 209 GLU GLU B . n 
B 1 231 GLY 231 210 210 GLY GLY B . n 
B 1 232 ARG 232 211 211 ARG ARG B . n 
B 1 233 ILE 233 212 212 ILE ILE B . n 
B 1 234 THR 234 213 213 THR THR B . n 
B 1 235 ALA 235 214 214 ALA ALA B . n 
B 1 236 ARG 236 215 215 ARG ARG B . n 
B 1 237 PRO 237 216 216 PRO PRO B . n 
B 1 238 ASP 238 217 217 ASP ASP B . n 
B 1 239 CYS 239 218 218 CYS CYS B . n 
B 1 240 VAL 240 219 219 VAL VAL B . n 
B 1 241 LEU 241 220 220 LEU LEU B . n 
B 1 242 GLU 242 221 221 GLU GLU B . n 
B 1 243 HIS 243 222 222 HIS HIS B . n 
B 1 244 MET 244 223 223 MET MET B . n 
B 1 245 ALA 245 224 224 ALA ALA B . n 
B 1 246 GLN 246 225 225 GLN GLN B . n 
B 1 247 LEU 247 226 226 LEU LEU B . n 
B 1 248 THR 248 227 227 THR THR B . n 
B 1 249 ASP 249 228 228 ASP ASP B . n 
B 1 250 ALA 250 229 229 ALA ALA B . n 
B 1 251 SER 251 230 230 SER SER B . n 
B 1 252 GLY 252 231 231 GLY GLY B . n 
B 1 253 GLU 253 232 232 GLU GLU B . n 
B 1 254 ARG 254 233 233 ARG ARG B . n 
B 1 255 VAL 255 234 234 VAL VAL B . n 
B 1 256 ASP 256 235 235 ASP ASP B . n 
B 1 257 ALA 257 236 236 ALA ALA B . n 
B 1 258 ARG 258 237 237 ARG ARG B . n 
B 1 259 THR 259 238 238 THR THR B . n 
B 1 260 ALA 260 239 239 ALA ALA B . n 
B 1 261 GLY 261 240 240 GLY GLY B . n 
B 1 262 ILE 262 241 241 ILE ILE B . n 
B 1 263 GLU 263 242 242 GLU GLU B . n 
B 1 264 LEU 264 243 243 LEU LEU B . n 
B 1 265 GLN 265 244 244 GLN GLN B . n 
B 1 266 ASN 266 245 245 ASN ASN B . n 
B 1 267 LEU 267 246 246 LEU LEU B . n 
B 1 268 THR 268 247 247 THR THR B . n 
B 1 269 ARG 269 248 248 ARG ARG B . n 
B 1 270 PRO 270 249 249 PRO PRO B . n 
B 1 271 THR 271 250 250 THR THR B . n 
B 1 272 VAL 272 251 251 VAL VAL B . n 
B 1 273 ALA 273 252 252 ALA ALA B . n 
B 1 274 VAL 274 253 253 VAL VAL B . n 
B 1 275 GLY 275 254 254 GLY GLY B . n 
B 1 276 PHE 276 255 255 PHE PHE B . n 
B 1 277 PHE 277 256 256 PHE PHE B . n 
B 1 278 ALA 278 257 257 ALA ALA B . n 
B 1 279 SER 279 258 258 SER SER B . n 
B 1 280 PHE 280 259 259 PHE PHE B . n 
B 1 281 ALA 281 260 260 ALA ALA B . n 
B 1 282 ALA 282 261 261 ALA ALA B . n 
B 1 283 VAL 283 262 262 VAL VAL B . n 
B 1 284 ALA 284 263 263 ALA ALA B . n 
B 1 285 LEU 285 264 264 LEU LEU B . n 
B 1 286 ALA 286 265 265 ALA ALA B . n 
B 1 287 GLU 287 266 266 GLU GLU B . n 
B 1 288 ASN 288 267 267 ASN ASN B . n 
B 1 289 PRO 289 268 268 PRO PRO B . n 
B 1 290 GLN 290 269 269 GLN GLN B . n 
B 1 291 TRP 291 270 270 TRP TRP B . n 
B 1 292 ARG 292 271 271 ARG ARG B . n 
B 1 293 THR 293 272 272 THR THR B . n 
B 1 294 ARG 294 273 273 ARG ARG B . n 
B 1 295 ILE 295 274 274 ILE ILE B . n 
B 1 296 ASN 296 275 275 ASN ASN B . n 
B 1 297 GLU 297 276 276 GLU GLU B . n 
B 1 298 SER 298 277 277 SER SER B . n 
B 1 299 GLU 299 278 278 GLU GLU B . n 
B 1 300 THR 300 279 279 THR THR B . n 
B 1 301 GLY 301 280 280 GLY GLY B . n 
B 1 302 ARG 302 281 281 ARG ARG B . n 
B 1 303 GLU 303 282 282 GLU GLU B . n 
B 1 304 ALA 304 283 283 ALA ALA B . n 
B 1 305 PHE 305 284 284 PHE PHE B . n 
B 1 306 ALA 306 285 285 ALA ALA B . n 
B 1 307 PHE 307 286 286 PHE PHE B . n 
B 1 308 ALA 308 287 287 ALA ALA B . n 
B 1 309 GLN 309 288 288 GLN GLN B . n 
B 1 310 GLU 310 289 289 GLU GLU B . n 
B 1 311 VAL 311 290 290 VAL VAL B . n 
B 1 312 ARG 312 291 291 ARG ARG B . n 
B 1 313 ARG 313 292 292 ARG ARG B . n 
B 1 314 PHE 314 293 293 PHE PHE B . n 
B 1 315 TYR 315 294 294 TYR TYR B . n 
B 1 316 PRO 316 295 295 PRO PRO B . n 
B 1 317 PHE 317 296 296 PHE PHE B . n 
B 1 318 VAL 318 297 297 VAL VAL B . n 
B 1 319 PRO 319 298 298 PRO PRO B . n 
B 1 320 MET 320 299 299 MET MET B . n 
B 1 321 PHE 321 300 300 PHE PHE B . n 
B 1 322 PRO 322 301 301 PRO PRO B . n 
B 1 323 ALA 323 302 302 ALA ALA B . n 
B 1 324 LYS 324 303 303 LYS LYS B . n 
B 1 325 ALA 325 304 304 ALA ALA B . n 
B 1 326 THR 326 305 305 THR THR B . n 
B 1 327 LYS 327 306 306 LYS LYS B . n 
B 1 328 ASP 328 307 307 ASP ASP B . n 
B 1 329 THR 329 308 308 THR THR B . n 
B 1 330 GLU 330 309 309 GLU GLU B . n 
B 1 331 PHE 331 310 310 PHE PHE B . n 
B 1 332 GLU 332 311 311 GLU GLU B . n 
B 1 333 GLY 333 312 312 GLY GLY B . n 
B 1 334 CYS 334 313 313 CYS CYS B . n 
B 1 335 PRO 335 314 314 PRO PRO B . n 
B 1 336 ILE 336 315 315 ILE ILE B . n 
B 1 337 HIS 337 316 316 HIS HIS B . n 
B 1 338 GLN 338 317 317 GLN GLN B . n 
B 1 339 GLY 339 318 318 GLY GLY B . n 
B 1 340 GLN 340 319 319 GLN GLN B . n 
B 1 341 ARG 341 320 320 ARG ARG B . n 
B 1 342 VAL 342 321 321 VAL VAL B . n 
B 1 343 ILE 343 322 322 ILE ILE B . n 
B 1 344 LEU 344 323 323 LEU LEU B . n 
B 1 345 ASP 345 324 324 ASP ASP B . n 
B 1 346 PHE 346 325 325 PHE PHE B . n 
B 1 347 VAL 347 326 326 VAL VAL B . n 
B 1 348 GLY 348 327 327 GLY GLY B . n 
B 1 349 THR 349 328 328 THR THR B . n 
B 1 350 LEU 350 329 329 LEU LEU B . n 
B 1 351 HIS 351 330 330 HIS HIS B . n 
B 1 352 SER 352 331 331 SER SER B . n 
B 1 353 ALA 353 332 332 ALA ALA B . n 
B 1 354 GLU 354 333 333 GLU GLU B . n 
B 1 355 GLU 355 334 334 GLU GLU B . n 
B 1 356 TRP 356 335 335 TRP TRP B . n 
B 1 357 ASP 357 336 336 ASP ASP B . n 
B 1 358 ASN 358 337 337 ASN ASN B . n 
B 1 359 PRO 359 338 338 PRO PRO B . n 
B 1 360 ALA 360 339 339 ALA ALA B . n 
B 1 361 SER 361 340 340 SER SER B . n 
B 1 362 PHE 362 341 341 PHE PHE B . n 
B 1 363 ASP 363 342 342 ASP ASP B . n 
B 1 364 PRO 364 343 343 PRO PRO B . n 
B 1 365 GLU 365 344 344 GLU GLU B . n 
B 1 366 ARG 366 345 345 ARG ARG B . n 
B 1 367 PHE 367 346 346 PHE PHE B . n 
B 1 368 MET 368 347 347 MET MET B . n 
B 1 369 ALA 369 348 348 ALA ALA B . n 
B 1 370 TYR 370 349 349 TYR TYR B . n 
B 1 371 GLU 371 350 350 GLU GLU B . n 
B 1 372 THR 372 351 351 THR THR B . n 
B 1 373 GLN 373 352 352 GLN GLN B . n 
B 1 374 SER 374 353 353 SER SER B . n 
B 1 375 GLU 375 354 354 GLU GLU B . n 
B 1 376 ALA 376 355 355 ALA ALA B . n 
B 1 377 GLU 377 356 356 GLU GLU B . n 
B 1 378 THR 378 357 357 THR THR B . n 
B 1 379 ILE 379 358 358 ILE ILE B . n 
B 1 380 LYS 380 359 359 LYS LYS B . n 
B 1 381 PRO 381 360 360 PRO PRO B . n 
B 1 382 PHE 382 361 361 PHE PHE B . n 
B 1 383 ILE 383 362 362 ILE ILE B . n 
B 1 384 PRO 384 363 363 PRO PRO B . n 
B 1 385 GLN 385 364 364 GLN GLN B . n 
B 1 386 GLY 386 365 365 GLY GLY B . n 
B 1 387 GLY 387 366 366 GLY GLY B . n 
B 1 388 ALA 388 367 367 ALA ALA B . n 
B 1 389 ASP 389 368 368 ASP ASP B . n 
B 1 390 VAL 390 369 369 VAL VAL B . n 
B 1 391 ARG 391 370 370 ARG ARG B . n 
B 1 392 THR 392 371 371 THR THR B . n 
B 1 393 GLY 393 372 372 GLY GLY B . n 
B 1 394 HIS 394 373 373 HIS HIS B . n 
B 1 395 ARG 395 374 374 ARG ARG B . n 
B 1 396 CYS 396 375 375 CYS CYS B . n 
B 1 397 PRO 397 376 376 PRO PRO B . n 
B 1 398 GLY 398 377 377 GLY GLY B . n 
B 1 399 GLU 399 378 378 GLU GLU B . n 
B 1 400 LYS 400 379 379 LYS LYS B . n 
B 1 401 ILE 401 380 380 ILE ILE B . n 
B 1 402 ALA 402 381 381 ALA ALA B . n 
B 1 403 VAL 403 382 382 VAL VAL B . n 
B 1 404 THR 404 383 383 THR THR B . n 
B 1 405 ALA 405 384 384 ALA ALA B . n 
B 1 406 LEU 406 385 385 LEU LEU B . n 
B 1 407 SER 407 386 386 SER SER B . n 
B 1 408 ALA 408 387 387 ALA ALA B . n 
B 1 409 ALA 409 388 388 ALA ALA B . n 
B 1 410 VAL 410 389 389 VAL VAL B . n 
B 1 411 GLU 411 390 390 GLU GLU B . n 
B 1 412 ALA 412 391 391 ALA ALA B . n 
B 1 413 LEU 413 392 392 LEU LEU B . n 
B 1 414 ALA 414 393 393 ALA ALA B . n 
B 1 415 ARG 415 394 394 ARG ARG B . n 
B 1 416 PRO 416 395 395 PRO PRO B . n 
B 1 417 GLU 417 396 396 GLU GLU B . n 
B 1 418 VAL 418 397 397 VAL VAL B . n 
B 1 419 ARG 419 398 398 ARG ARG B . n 
B 1 420 ILE 420 399 399 ILE ILE B . n 
B 1 421 SER 421 400 400 SER SER B . n 
B 1 422 ALA 422 401 401 ALA ALA B . n 
B 1 423 GLU 423 402 402 GLU GLU B . n 
B 1 424 ALA 424 403 403 ALA ALA B . n 
B 1 425 ILE 425 404 404 ILE ILE B . n 
B 1 426 ASP 426 405 405 ASP ASP B . n 
B 1 427 ILE 427 406 406 ILE ILE B . n 
B 1 428 ASN 428 407 407 ASN ASN B . n 
B 1 429 TYR 429 408 408 TYR TYR B . n 
B 1 430 SER 430 409 409 SER SER B . n 
B 1 431 MET 431 410 410 MET MET B . n 
B 1 432 THR 432 411 411 THR THR B . n 
B 1 433 GLU 433 412 412 GLU GLU B . n 
B 1 434 ILE 434 413 413 ILE ILE B . n 
B 1 435 LEU 435 414 414 LEU LEU B . n 
B 1 436 ALA 436 415 415 ALA ALA B . n 
B 1 437 ARG 437 416 416 ARG ARG B . n 
B 1 438 PRO 438 417 417 PRO PRO B . n 
B 1 439 LYS 439 418 418 LYS LYS B . n 
B 1 440 SER 440 419 419 SER SER B . n 
B 1 441 GLY 441 420 420 GLY GLY B . n 
B 1 442 VAL 442 421 421 VAL VAL B . n 
B 1 443 ARG 443 422 422 ARG ARG B . n 
B 1 444 VAL 444 423 423 VAL VAL B . n 
B 1 445 THR 445 424 424 THR THR B . n 
B 1 446 VAL 446 425 425 VAL VAL B . n 
B 1 447 ALA 447 426 426 ALA ALA B . n 
B 1 448 SER 448 427 427 SER SER B . n 
B 1 449 SER 449 428 428 SER SER B . n 
B 1 450 SER 450 429 ?   ?   ?   B . n 
C 1 1   MET 1   -20 ?   ?   ?   C . n 
C 1 2   GLY 2   -19 ?   ?   ?   C . n 
C 1 3   SER 3   -18 ?   ?   ?   C . n 
C 1 4   SER 4   -17 ?   ?   ?   C . n 
C 1 5   HIS 5   -16 ?   ?   ?   C . n 
C 1 6   HIS 6   -15 ?   ?   ?   C . n 
C 1 7   HIS 7   -14 ?   ?   ?   C . n 
C 1 8   HIS 8   -13 ?   ?   ?   C . n 
C 1 9   HIS 9   -12 ?   ?   ?   C . n 
C 1 10  HIS 10  -11 ?   ?   ?   C . n 
C 1 11  SER 11  -10 ?   ?   ?   C . n 
C 1 12  SER 12  -9  ?   ?   ?   C . n 
C 1 13  GLY 13  -8  ?   ?   ?   C . n 
C 1 14  LEU 14  -7  ?   ?   ?   C . n 
C 1 15  VAL 15  -6  ?   ?   ?   C . n 
C 1 16  PRO 16  -5  ?   ?   ?   C . n 
C 1 17  ARG 17  -4  ?   ?   ?   C . n 
C 1 18  GLY 18  -3  ?   ?   ?   C . n 
C 1 19  SER 19  -2  ?   ?   ?   C . n 
C 1 20  HIS 20  -1  ?   ?   ?   C . n 
C 1 21  MET 21  0   ?   ?   ?   C . n 
C 1 22  MET 22  1   ?   ?   ?   C . n 
C 1 23  ARG 23  2   ?   ?   ?   C . n 
C 1 24  MET 24  3   ?   ?   ?   C . n 
C 1 25  THR 25  4   ?   ?   ?   C . n 
C 1 26  SER 26  5   ?   ?   ?   C . n 
C 1 27  ASN 27  6   ?   ?   ?   C . n 
C 1 28  GLN 28  7   ?   ?   ?   C . n 
C 1 29  ASN 29  8   8   ASN ASN C . n 
C 1 30  PRO 30  9   9   PRO PRO C . n 
C 1 31  ARG 31  10  10  ARG ARG C . n 
C 1 32  VAL 32  11  11  VAL VAL C . n 
C 1 33  SER 33  12  12  SER SER C . n 
C 1 34  GLY 34  13  13  GLY GLY C . n 
C 1 35  ASP 35  14  14  ASP ASP C . n 
C 1 36  ARG 36  15  15  ARG ARG C . n 
C 1 37  THR 37  16  16  THR THR C . n 
C 1 38  ILE 38  17  17  ILE ILE C . n 
C 1 39  GLN 39  18  18  GLN GLN C . n 
C 1 40  PHE 40  19  19  PHE PHE C . n 
C 1 41  LEU 41  20  20  LEU LEU C . n 
C 1 42  THR 42  21  21  THR THR C . n 
C 1 43  ASP 43  22  22  ASP ASP C . n 
C 1 44  GLY 44  23  23  GLY GLY C . n 
C 1 45  TYR 45  24  24  TYR TYR C . n 
C 1 46  LEU 46  25  25  LEU LEU C . n 
C 1 47  LEU 47  26  26  LEU LEU C . n 
C 1 48  PRO 48  27  27  PRO PRO C . n 
C 1 49  SER 49  28  28  SER SER C . n 
C 1 50  ASN 50  29  29  ASN ASN C . n 
C 1 51  LEU 51  30  30  LEU LEU C . n 
C 1 52  ARG 52  31  31  ARG ARG C . n 
C 1 53  LYS 53  32  32  LYS LYS C . n 
C 1 54  THR 54  33  33  THR THR C . n 
C 1 55  ALA 55  34  34  ALA ALA C . n 
C 1 56  GLY 56  35  35  GLY GLY C . n 
C 1 57  LEU 57  36  36  LEU LEU C . n 
C 1 58  GLU 58  37  37  GLU GLU C . n 
C 1 59  PRO 59  38  38  PRO PRO C . n 
C 1 60  GLU 60  39  39  GLU GLU C . n 
C 1 61  SER 61  40  40  SER SER C . n 
C 1 62  MET 62  41  41  MET MET C . n 
C 1 63  CYS 63  42  42  CYS CYS C . n 
C 1 64  PRO 64  43  43  PRO PRO C . n 
C 1 65  VAL 65  44  44  VAL VAL C . n 
C 1 66  THR 66  45  45  THR THR C . n 
C 1 67  THR 67  46  46  THR THR C . n 
C 1 68  LYS 68  47  47  LYS LYS C . n 
C 1 69  LEU 69  48  48  LEU LEU C . n 
C 1 70  LEU 70  49  49  LEU LEU C . n 
C 1 71  GLY 71  50  50  GLY GLY C . n 
C 1 72  GLN 72  51  51  GLN GLN C . n 
C 1 73  ASP 73  52  52  ASP ASP C . n 
C 1 74  ALA 74  53  53  ALA ALA C . n 
C 1 75  THR 75  54  54  THR THR C . n 
C 1 76  ILE 76  55  55  ILE ILE C . n 
C 1 77  VAL 77  56  56  VAL VAL C . n 
C 1 78  ARG 78  57  57  ARG ARG C . n 
C 1 79  GLY 79  58  58  GLY GLY C . n 
C 1 80  SER 80  59  59  SER SER C . n 
C 1 81  ALA 81  60  60  ALA ALA C . n 
C 1 82  GLY 82  61  61  GLY GLY C . n 
C 1 83  ILE 83  62  62  ILE ILE C . n 
C 1 84  ASP 84  63  63  ASP ASP C . n 
C 1 85  LEU 85  64  64  LEU LEU C . n 
C 1 86  PHE 86  65  65  PHE PHE C . n 
C 1 87  TYR 87  66  66  TYR TYR C . n 
C 1 88  ASP 88  67  67  ASP ASP C . n 
C 1 89  GLU 89  68  68  GLU GLU C . n 
C 1 90  ASP 90  69  69  ASP ASP C . n 
C 1 91  VAL 91  70  70  VAL VAL C . n 
C 1 92  MET 92  71  71  MET MET C . n 
C 1 93  GLN 93  72  72  GLN GLN C . n 
C 1 94  ARG 94  73  73  ARG ARG C . n 
C 1 95  GLU 95  74  74  GLU GLU C . n 
C 1 96  GLY 96  75  75  GLY GLY C . n 
C 1 97  ALA 97  76  76  ALA ALA C . n 
C 1 98  MET 98  77  77  MET MET C . n 
C 1 99  PRO 99  78  78  PRO PRO C . n 
C 1 100 PRO 100 79  79  PRO PRO C . n 
C 1 101 VAL 101 80  80  VAL VAL C . n 
C 1 102 ILE 102 81  81  ILE ILE C . n 
C 1 103 GLY 103 82  82  GLY GLY C . n 
C 1 104 ASP 104 83  83  ASP ASP C . n 
C 1 105 ALA 105 84  84  ALA ALA C . n 
C 1 106 LEU 106 85  85  LEU LEU C . n 
C 1 107 VAL 107 86  86  VAL VAL C . n 
C 1 108 GLY 108 87  87  GLY GLY C . n 
C 1 109 LYS 109 88  88  LYS LYS C . n 
C 1 110 GLY 110 89  89  GLY GLY C . n 
C 1 111 ALA 111 90  90  ALA ALA C . n 
C 1 112 VAL 112 91  91  VAL VAL C . n 
C 1 113 HIS 113 92  92  HIS HIS C . n 
C 1 114 ASN 114 93  93  ASN ASN C . n 
C 1 115 LEU 115 94  94  LEU LEU C . n 
C 1 116 ASP 116 95  95  ASP ASP C . n 
C 1 117 GLY 117 96  96  GLY GLY C . n 
C 1 118 GLU 118 97  97  GLU GLU C . n 
C 1 119 GLU 119 98  98  GLU GLU C . n 
C 1 120 HIS 120 99  99  HIS HIS C . n 
C 1 121 LYS 121 100 100 LYS LYS C . n 
C 1 122 VAL 122 101 101 VAL VAL C . n 
C 1 123 ARG 123 102 102 ARG ARG C . n 
C 1 124 LYS 124 103 103 LYS LYS C . n 
C 1 125 ALA 125 104 104 ALA ALA C . n 
C 1 126 GLN 126 105 105 GLN GLN C . n 
C 1 127 MET 127 106 106 MET MET C . n 
C 1 128 ALA 128 107 107 ALA ALA C . n 
C 1 129 ALA 129 108 108 ALA ALA C . n 
C 1 130 MET 130 109 109 MET MET C . n 
C 1 131 ALA 131 110 110 ALA ALA C . n 
C 1 132 TYR 132 111 111 TYR TYR C . n 
C 1 133 GLU 133 112 112 GLU GLU C . n 
C 1 134 ASP 134 113 113 ASP ASP C . n 
C 1 135 GLU 135 114 114 GLU GLU C . n 
C 1 136 ARG 136 115 115 ARG ARG C . n 
C 1 137 VAL 137 116 116 VAL VAL C . n 
C 1 138 ALA 138 117 117 ALA ALA C . n 
C 1 139 GLU 139 118 118 GLU GLU C . n 
C 1 140 PHE 140 119 119 PHE PHE C . n 
C 1 141 ALA 141 120 120 ALA ALA C . n 
C 1 142 PRO 142 121 121 PRO PRO C . n 
C 1 143 LEU 143 122 122 LEU LEU C . n 
C 1 144 VAL 144 123 123 VAL VAL C . n 
C 1 145 ALA 145 124 124 ALA ALA C . n 
C 1 146 GLU 146 125 125 GLU GLU C . n 
C 1 147 GLU 147 126 126 GLU GLU C . n 
C 1 148 VAL 148 127 127 VAL VAL C . n 
C 1 149 GLU 149 128 128 GLU GLU C . n 
C 1 150 ARG 150 129 129 ARG ARG C . n 
C 1 151 ALA 151 130 130 ALA ALA C . n 
C 1 152 VAL 152 131 131 VAL VAL C . n 
C 1 153 ALA 153 132 132 ALA ALA C . n 
C 1 154 GLY 154 133 133 GLY GLY C . n 
C 1 155 TRP 155 134 134 TRP TRP C . n 
C 1 156 GLU 156 135 135 GLU GLU C . n 
C 1 157 GLY 157 136 136 GLY GLY C . n 
C 1 158 ALA 158 137 137 ALA ALA C . n 
C 1 159 GLN 159 138 138 GLN GLN C . n 
C 1 160 GLY 160 139 139 GLY GLY C . n 
C 1 161 ASN 161 140 140 ASN ASN C . n 
C 1 162 VAL 162 141 141 VAL VAL C . n 
C 1 163 PHE 163 142 142 PHE PHE C . n 
C 1 164 GLU 164 143 143 GLU GLU C . n 
C 1 165 ASP 165 144 144 ASP ASP C . n 
C 1 166 LEU 166 145 145 LEU LEU C . n 
C 1 167 SER 167 146 146 SER SER C . n 
C 1 168 LEU 168 147 147 LEU LEU C . n 
C 1 169 ALA 169 148 148 ALA ALA C . n 
C 1 170 PHE 170 149 149 PHE PHE C . n 
C 1 171 GLY 171 150 150 GLY GLY C . n 
C 1 172 ARG 172 151 151 ARG ARG C . n 
C 1 173 ALA 173 152 152 ALA ALA C . n 
C 1 174 ALA 174 153 153 ALA ALA C . n 
C 1 175 PHE 175 154 154 PHE PHE C . n 
C 1 176 ARG 176 155 155 ARG ARG C . n 
C 1 177 TRP 177 156 156 TRP TRP C . n 
C 1 178 ALA 178 157 157 ALA ALA C . n 
C 1 179 GLY 179 158 158 GLY GLY C . n 
C 1 180 ILE 180 159 159 ILE ILE C . n 
C 1 181 ASP 181 160 160 ASP ASP C . n 
C 1 182 LEU 182 161 161 LEU LEU C . n 
C 1 183 PRO 183 162 162 PRO PRO C . n 
C 1 184 ALA 184 163 163 ALA ALA C . n 
C 1 185 GLU 185 164 164 GLU GLU C . n 
C 1 186 ASN 186 165 165 ASN ASN C . n 
C 1 187 THR 187 166 166 THR THR C . n 
C 1 188 ASP 188 167 167 ASP ASP C . n 
C 1 189 GLU 189 168 168 GLU GLU C . n 
C 1 190 LEU 190 169 169 LEU LEU C . n 
C 1 191 VAL 191 170 170 VAL VAL C . n 
C 1 192 GLY 192 171 171 GLY GLY C . n 
C 1 193 ARG 193 172 172 ARG ARG C . n 
C 1 194 MET 194 173 173 MET MET C . n 
C 1 195 ILE 195 174 174 ILE ILE C . n 
C 1 196 THR 196 175 175 THR THR C . n 
C 1 197 LEU 197 176 176 LEU LEU C . n 
C 1 198 LEU 198 177 177 LEU LEU C . n 
C 1 199 ASP 199 178 178 ASP ASP C . n 
C 1 200 ASN 200 179 179 ASN ASN C . n 
C 1 201 PHE 201 180 180 PHE PHE C . n 
C 1 202 GLY 202 181 181 GLY GLY C . n 
C 1 203 THR 203 182 182 THR THR C . n 
C 1 204 ALA 204 183 183 ALA ALA C . n 
C 1 205 THR 205 184 184 THR THR C . n 
C 1 206 GLY 206 185 185 GLY GLY C . n 
C 1 207 THR 207 186 186 THR THR C . n 
C 1 208 PRO 208 187 187 PRO PRO C . n 
C 1 209 LYS 209 188 188 LYS LYS C . n 
C 1 210 ALA 210 189 189 ALA ALA C . n 
C 1 211 PHE 211 190 190 PHE PHE C . n 
C 1 212 TRP 212 191 191 TRP TRP C . n 
C 1 213 GLN 213 192 192 GLN GLN C . n 
C 1 214 ARG 214 193 193 ARG ARG C . n 
C 1 215 ARG 215 194 194 ARG ARG C . n 
C 1 216 GLN 216 195 195 GLN GLN C . n 
C 1 217 LEU 217 196 196 LEU LEU C . n 
C 1 218 ASP 218 197 197 ASP ASP C . n 
C 1 219 ASN 219 198 198 ASN ASN C . n 
C 1 220 TRP 220 199 199 TRP TRP C . n 
C 1 221 ALA 221 200 200 ALA ALA C . n 
C 1 222 GLU 222 201 201 GLU GLU C . n 
C 1 223 ALA 223 202 202 ALA ALA C . n 
C 1 224 LEU 224 203 203 LEU LEU C . n 
C 1 225 ILE 225 204 204 ILE ILE C . n 
C 1 226 THR 226 205 205 THR THR C . n 
C 1 227 ASP 227 206 206 ASP ASP C . n 
C 1 228 VAL 228 207 207 VAL VAL C . n 
C 1 229 ARG 229 208 208 ARG ARG C . n 
C 1 230 GLU 230 209 209 GLU GLU C . n 
C 1 231 GLY 231 210 210 GLY GLY C . n 
C 1 232 ARG 232 211 211 ARG ARG C . n 
C 1 233 ILE 233 212 212 ILE ILE C . n 
C 1 234 THR 234 213 213 THR THR C . n 
C 1 235 ALA 235 214 214 ALA ALA C . n 
C 1 236 ARG 236 215 215 ARG ARG C . n 
C 1 237 PRO 237 216 216 PRO PRO C . n 
C 1 238 ASP 238 217 217 ASP ASP C . n 
C 1 239 CYS 239 218 218 CYS CYS C . n 
C 1 240 VAL 240 219 219 VAL VAL C . n 
C 1 241 LEU 241 220 220 LEU LEU C . n 
C 1 242 GLU 242 221 221 GLU GLU C . n 
C 1 243 HIS 243 222 222 HIS HIS C . n 
C 1 244 MET 244 223 223 MET MET C . n 
C 1 245 ALA 245 224 224 ALA ALA C . n 
C 1 246 GLN 246 225 225 GLN GLN C . n 
C 1 247 LEU 247 226 226 LEU LEU C . n 
C 1 248 THR 248 227 227 THR THR C . n 
C 1 249 ASP 249 228 228 ASP ASP C . n 
C 1 250 ALA 250 229 229 ALA ALA C . n 
C 1 251 SER 251 230 230 SER SER C . n 
C 1 252 GLY 252 231 231 GLY GLY C . n 
C 1 253 GLU 253 232 232 GLU GLU C . n 
C 1 254 ARG 254 233 233 ARG ARG C . n 
C 1 255 VAL 255 234 234 VAL VAL C . n 
C 1 256 ASP 256 235 235 ASP ASP C . n 
C 1 257 ALA 257 236 236 ALA ALA C . n 
C 1 258 ARG 258 237 237 ARG ARG C . n 
C 1 259 THR 259 238 238 THR THR C . n 
C 1 260 ALA 260 239 239 ALA ALA C . n 
C 1 261 GLY 261 240 240 GLY GLY C . n 
C 1 262 ILE 262 241 241 ILE ILE C . n 
C 1 263 GLU 263 242 242 GLU GLU C . n 
C 1 264 LEU 264 243 243 LEU LEU C . n 
C 1 265 GLN 265 244 244 GLN GLN C . n 
C 1 266 ASN 266 245 245 ASN ASN C . n 
C 1 267 LEU 267 246 246 LEU LEU C . n 
C 1 268 THR 268 247 247 THR THR C . n 
C 1 269 ARG 269 248 248 ARG ARG C . n 
C 1 270 PRO 270 249 249 PRO PRO C . n 
C 1 271 THR 271 250 250 THR THR C . n 
C 1 272 VAL 272 251 251 VAL VAL C . n 
C 1 273 ALA 273 252 252 ALA ALA C . n 
C 1 274 VAL 274 253 253 VAL VAL C . n 
C 1 275 GLY 275 254 254 GLY GLY C . n 
C 1 276 PHE 276 255 255 PHE PHE C . n 
C 1 277 PHE 277 256 256 PHE PHE C . n 
C 1 278 ALA 278 257 257 ALA ALA C . n 
C 1 279 SER 279 258 258 SER SER C . n 
C 1 280 PHE 280 259 259 PHE PHE C . n 
C 1 281 ALA 281 260 260 ALA ALA C . n 
C 1 282 ALA 282 261 261 ALA ALA C . n 
C 1 283 VAL 283 262 262 VAL VAL C . n 
C 1 284 ALA 284 263 263 ALA ALA C . n 
C 1 285 LEU 285 264 264 LEU LEU C . n 
C 1 286 ALA 286 265 265 ALA ALA C . n 
C 1 287 GLU 287 266 266 GLU GLU C . n 
C 1 288 ASN 288 267 267 ASN ASN C . n 
C 1 289 PRO 289 268 268 PRO PRO C . n 
C 1 290 GLN 290 269 269 GLN GLN C . n 
C 1 291 TRP 291 270 270 TRP TRP C . n 
C 1 292 ARG 292 271 271 ARG ARG C . n 
C 1 293 THR 293 272 272 THR THR C . n 
C 1 294 ARG 294 273 273 ARG ARG C . n 
C 1 295 ILE 295 274 274 ILE ILE C . n 
C 1 296 ASN 296 275 275 ASN ASN C . n 
C 1 297 GLU 297 276 276 GLU GLU C . n 
C 1 298 SER 298 277 277 SER SER C . n 
C 1 299 GLU 299 278 278 GLU GLU C . n 
C 1 300 THR 300 279 279 THR THR C . n 
C 1 301 GLY 301 280 280 GLY GLY C . n 
C 1 302 ARG 302 281 281 ARG ARG C . n 
C 1 303 GLU 303 282 282 GLU GLU C . n 
C 1 304 ALA 304 283 283 ALA ALA C . n 
C 1 305 PHE 305 284 284 PHE PHE C . n 
C 1 306 ALA 306 285 285 ALA ALA C . n 
C 1 307 PHE 307 286 286 PHE PHE C . n 
C 1 308 ALA 308 287 287 ALA ALA C . n 
C 1 309 GLN 309 288 288 GLN GLN C . n 
C 1 310 GLU 310 289 289 GLU GLU C . n 
C 1 311 VAL 311 290 290 VAL VAL C . n 
C 1 312 ARG 312 291 291 ARG ARG C . n 
C 1 313 ARG 313 292 292 ARG ARG C . n 
C 1 314 PHE 314 293 293 PHE PHE C . n 
C 1 315 TYR 315 294 294 TYR TYR C . n 
C 1 316 PRO 316 295 295 PRO PRO C . n 
C 1 317 PHE 317 296 296 PHE PHE C . n 
C 1 318 VAL 318 297 297 VAL VAL C . n 
C 1 319 PRO 319 298 298 PRO PRO C . n 
C 1 320 MET 320 299 299 MET MET C . n 
C 1 321 PHE 321 300 300 PHE PHE C . n 
C 1 322 PRO 322 301 301 PRO PRO C . n 
C 1 323 ALA 323 302 302 ALA ALA C . n 
C 1 324 LYS 324 303 303 LYS LYS C . n 
C 1 325 ALA 325 304 304 ALA ALA C . n 
C 1 326 THR 326 305 305 THR THR C . n 
C 1 327 LYS 327 306 306 LYS LYS C . n 
C 1 328 ASP 328 307 307 ASP ASP C . n 
C 1 329 THR 329 308 308 THR THR C . n 
C 1 330 GLU 330 309 309 GLU GLU C . n 
C 1 331 PHE 331 310 310 PHE PHE C . n 
C 1 332 GLU 332 311 311 GLU GLU C . n 
C 1 333 GLY 333 312 312 GLY GLY C . n 
C 1 334 CYS 334 313 313 CYS CYS C . n 
C 1 335 PRO 335 314 314 PRO PRO C . n 
C 1 336 ILE 336 315 315 ILE ILE C . n 
C 1 337 HIS 337 316 316 HIS HIS C . n 
C 1 338 GLN 338 317 317 GLN GLN C . n 
C 1 339 GLY 339 318 318 GLY GLY C . n 
C 1 340 GLN 340 319 319 GLN GLN C . n 
C 1 341 ARG 341 320 320 ARG ARG C . n 
C 1 342 VAL 342 321 321 VAL VAL C . n 
C 1 343 ILE 343 322 322 ILE ILE C . n 
C 1 344 LEU 344 323 323 LEU LEU C . n 
C 1 345 ASP 345 324 324 ASP ASP C . n 
C 1 346 PHE 346 325 325 PHE PHE C . n 
C 1 347 VAL 347 326 326 VAL VAL C . n 
C 1 348 GLY 348 327 327 GLY GLY C . n 
C 1 349 THR 349 328 328 THR THR C . n 
C 1 350 LEU 350 329 329 LEU LEU C . n 
C 1 351 HIS 351 330 330 HIS HIS C . n 
C 1 352 SER 352 331 331 SER SER C . n 
C 1 353 ALA 353 332 332 ALA ALA C . n 
C 1 354 GLU 354 333 333 GLU GLU C . n 
C 1 355 GLU 355 334 334 GLU GLU C . n 
C 1 356 TRP 356 335 335 TRP TRP C . n 
C 1 357 ASP 357 336 336 ASP ASP C . n 
C 1 358 ASN 358 337 337 ASN ASN C . n 
C 1 359 PRO 359 338 338 PRO PRO C . n 
C 1 360 ALA 360 339 339 ALA ALA C . n 
C 1 361 SER 361 340 340 SER SER C . n 
C 1 362 PHE 362 341 341 PHE PHE C . n 
C 1 363 ASP 363 342 342 ASP ASP C . n 
C 1 364 PRO 364 343 343 PRO PRO C . n 
C 1 365 GLU 365 344 344 GLU GLU C . n 
C 1 366 ARG 366 345 345 ARG ARG C . n 
C 1 367 PHE 367 346 346 PHE PHE C . n 
C 1 368 MET 368 347 347 MET MET C . n 
C 1 369 ALA 369 348 348 ALA ALA C . n 
C 1 370 TYR 370 349 349 TYR TYR C . n 
C 1 371 GLU 371 350 350 GLU GLU C . n 
C 1 372 THR 372 351 351 THR THR C . n 
C 1 373 GLN 373 352 352 GLN GLN C . n 
C 1 374 SER 374 353 353 SER SER C . n 
C 1 375 GLU 375 354 354 GLU GLU C . n 
C 1 376 ALA 376 355 355 ALA ALA C . n 
C 1 377 GLU 377 356 356 GLU GLU C . n 
C 1 378 THR 378 357 357 THR THR C . n 
C 1 379 ILE 379 358 358 ILE ILE C . n 
C 1 380 LYS 380 359 359 LYS LYS C . n 
C 1 381 PRO 381 360 360 PRO PRO C . n 
C 1 382 PHE 382 361 361 PHE PHE C . n 
C 1 383 ILE 383 362 362 ILE ILE C . n 
C 1 384 PRO 384 363 363 PRO PRO C . n 
C 1 385 GLN 385 364 364 GLN GLN C . n 
C 1 386 GLY 386 365 365 GLY GLY C . n 
C 1 387 GLY 387 366 366 GLY GLY C . n 
C 1 388 ALA 388 367 367 ALA ALA C . n 
C 1 389 ASP 389 368 368 ASP ASP C . n 
C 1 390 VAL 390 369 369 VAL VAL C . n 
C 1 391 ARG 391 370 370 ARG ARG C . n 
C 1 392 THR 392 371 371 THR THR C . n 
C 1 393 GLY 393 372 372 GLY GLY C . n 
C 1 394 HIS 394 373 373 HIS HIS C . n 
C 1 395 ARG 395 374 374 ARG ARG C . n 
C 1 396 CYS 396 375 375 CYS CYS C . n 
C 1 397 PRO 397 376 376 PRO PRO C . n 
C 1 398 GLY 398 377 377 GLY GLY C . n 
C 1 399 GLU 399 378 378 GLU GLU C . n 
C 1 400 LYS 400 379 379 LYS LYS C . n 
C 1 401 ILE 401 380 380 ILE ILE C . n 
C 1 402 ALA 402 381 381 ALA ALA C . n 
C 1 403 VAL 403 382 382 VAL VAL C . n 
C 1 404 THR 404 383 383 THR THR C . n 
C 1 405 ALA 405 384 384 ALA ALA C . n 
C 1 406 LEU 406 385 385 LEU LEU C . n 
C 1 407 SER 407 386 386 SER SER C . n 
C 1 408 ALA 408 387 387 ALA ALA C . n 
C 1 409 ALA 409 388 388 ALA ALA C . n 
C 1 410 VAL 410 389 389 VAL VAL C . n 
C 1 411 GLU 411 390 390 GLU GLU C . n 
C 1 412 ALA 412 391 391 ALA ALA C . n 
C 1 413 LEU 413 392 392 LEU LEU C . n 
C 1 414 ALA 414 393 393 ALA ALA C . n 
C 1 415 ARG 415 394 394 ARG ARG C . n 
C 1 416 PRO 416 395 395 PRO PRO C . n 
C 1 417 GLU 417 396 396 GLU GLU C . n 
C 1 418 VAL 418 397 397 VAL VAL C . n 
C 1 419 ARG 419 398 398 ARG ARG C . n 
C 1 420 ILE 420 399 399 ILE ILE C . n 
C 1 421 SER 421 400 400 SER SER C . n 
C 1 422 ALA 422 401 401 ALA ALA C . n 
C 1 423 GLU 423 402 402 GLU GLU C . n 
C 1 424 ALA 424 403 403 ALA ALA C . n 
C 1 425 ILE 425 404 404 ILE ILE C . n 
C 1 426 ASP 426 405 405 ASP ASP C . n 
C 1 427 ILE 427 406 406 ILE ILE C . n 
C 1 428 ASN 428 407 407 ASN ASN C . n 
C 1 429 TYR 429 408 408 TYR TYR C . n 
C 1 430 SER 430 409 409 SER SER C . n 
C 1 431 MET 431 410 410 MET MET C . n 
C 1 432 THR 432 411 411 THR THR C . n 
C 1 433 GLU 433 412 412 GLU GLU C . n 
C 1 434 ILE 434 413 413 ILE ILE C . n 
C 1 435 LEU 435 414 414 LEU LEU C . n 
C 1 436 ALA 436 415 415 ALA ALA C . n 
C 1 437 ARG 437 416 416 ARG ARG C . n 
C 1 438 PRO 438 417 417 PRO PRO C . n 
C 1 439 LYS 439 418 418 LYS LYS C . n 
C 1 440 SER 440 419 419 SER SER C . n 
C 1 441 GLY 441 420 420 GLY GLY C . n 
C 1 442 VAL 442 421 421 VAL VAL C . n 
C 1 443 ARG 443 422 422 ARG ARG C . n 
C 1 444 VAL 444 423 423 VAL VAL C . n 
C 1 445 THR 445 424 424 THR THR C . n 
C 1 446 VAL 446 425 425 VAL VAL C . n 
C 1 447 ALA 447 426 ?   ?   ?   C . n 
C 1 448 SER 448 427 ?   ?   ?   C . n 
C 1 449 SER 449 428 ?   ?   ?   C . n 
C 1 450 SER 450 429 ?   ?   ?   C . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        OLA 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   OLA 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
D 2 HEM 1   501 1    HEM HEM A . 
E 3 OLA 1   502 1    OLA OLA A . 
F 4 PEG 1   503 1    PEG PEG A . 
G 5 GOL 1   504 1    GOL GOL A . 
H 5 GOL 1   505 3    GOL GOL A . 
I 5 GOL 1   506 5    GOL GOL A . 
J 6 CL  1   507 1    CL  CL  A . 
K 7 PGE 1   508 2    PGE PGE A . 
L 2 HEM 1   501 2    HEM HEM B . 
M 3 OLA 1   502 2    OLA OLA B . 
N 4 PEG 1   503 4    PEG PEG B . 
O 5 GOL 1   504 2    GOL GOL B . 
P 5 GOL 1   505 6    GOL GOL B . 
Q 7 PGE 1   506 1    PGE PGE B . 
R 2 HEM 1   501 3    HEM HEM C . 
S 3 OLA 1   502 3    OLA OLA C . 
T 4 PEG 1   503 3    PEG PEG C . 
U 5 GOL 1   504 4    GOL GOL C . 
V 6 CL  1   505 2    CL  CL  C . 
W 8 HOH 1   601 857  HOH HOH A . 
W 8 HOH 2   602 465  HOH HOH A . 
W 8 HOH 3   603 443  HOH HOH A . 
W 8 HOH 4   604 554  HOH HOH A . 
W 8 HOH 5   605 881  HOH HOH A . 
W 8 HOH 6   606 62   HOH HOH A . 
W 8 HOH 7   607 423  HOH HOH A . 
W 8 HOH 8   608 940  HOH HOH A . 
W 8 HOH 9   609 61   HOH HOH A . 
W 8 HOH 10  610 859  HOH HOH A . 
W 8 HOH 11  611 855  HOH HOH A . 
W 8 HOH 12  612 47   HOH HOH A . 
W 8 HOH 13  613 629  HOH HOH A . 
W 8 HOH 14  614 562  HOH HOH A . 
W 8 HOH 15  615 709  HOH HOH A . 
W 8 HOH 16  616 203  HOH HOH A . 
W 8 HOH 17  617 697  HOH HOH A . 
W 8 HOH 18  618 877  HOH HOH A . 
W 8 HOH 19  619 256  HOH HOH A . 
W 8 HOH 20  620 686  HOH HOH A . 
W 8 HOH 21  621 663  HOH HOH A . 
W 8 HOH 22  622 691  HOH HOH A . 
W 8 HOH 23  623 353  HOH HOH A . 
W 8 HOH 24  624 520  HOH HOH A . 
W 8 HOH 25  625 13   HOH HOH A . 
W 8 HOH 26  626 893  HOH HOH A . 
W 8 HOH 27  627 494  HOH HOH A . 
W 8 HOH 28  628 209  HOH HOH A . 
W 8 HOH 29  629 139  HOH HOH A . 
W 8 HOH 30  630 470  HOH HOH A . 
W 8 HOH 31  631 960  HOH HOH A . 
W 8 HOH 32  632 499  HOH HOH A . 
W 8 HOH 33  633 892  HOH HOH A . 
W 8 HOH 34  634 661  HOH HOH A . 
W 8 HOH 35  635 681  HOH HOH A . 
W 8 HOH 36  636 247  HOH HOH A . 
W 8 HOH 37  637 32   HOH HOH A . 
W 8 HOH 38  638 350  HOH HOH A . 
W 8 HOH 39  639 254  HOH HOH A . 
W 8 HOH 40  640 992  HOH HOH A . 
W 8 HOH 41  641 297  HOH HOH A . 
W 8 HOH 42  642 291  HOH HOH A . 
W 8 HOH 43  643 739  HOH HOH A . 
W 8 HOH 44  644 771  HOH HOH A . 
W 8 HOH 45  645 146  HOH HOH A . 
W 8 HOH 46  646 699  HOH HOH A . 
W 8 HOH 47  647 114  HOH HOH A . 
W 8 HOH 48  648 171  HOH HOH A . 
W 8 HOH 49  649 240  HOH HOH A . 
W 8 HOH 50  650 683  HOH HOH A . 
W 8 HOH 51  651 33   HOH HOH A . 
W 8 HOH 52  652 508  HOH HOH A . 
W 8 HOH 53  653 193  HOH HOH A . 
W 8 HOH 54  654 127  HOH HOH A . 
W 8 HOH 55  655 704  HOH HOH A . 
W 8 HOH 56  656 154  HOH HOH A . 
W 8 HOH 57  657 262  HOH HOH A . 
W 8 HOH 58  658 337  HOH HOH A . 
W 8 HOH 59  659 308  HOH HOH A . 
W 8 HOH 60  660 503  HOH HOH A . 
W 8 HOH 61  661 22   HOH HOH A . 
W 8 HOH 62  662 299  HOH HOH A . 
W 8 HOH 63  663 286  HOH HOH A . 
W 8 HOH 64  664 116  HOH HOH A . 
W 8 HOH 65  665 87   HOH HOH A . 
W 8 HOH 66  666 509  HOH HOH A . 
W 8 HOH 67  667 241  HOH HOH A . 
W 8 HOH 68  668 581  HOH HOH A . 
W 8 HOH 69  669 864  HOH HOH A . 
W 8 HOH 70  670 251  HOH HOH A . 
W 8 HOH 71  671 665  HOH HOH A . 
W 8 HOH 72  672 218  HOH HOH A . 
W 8 HOH 73  673 239  HOH HOH A . 
W 8 HOH 74  674 196  HOH HOH A . 
W 8 HOH 75  675 298  HOH HOH A . 
W 8 HOH 76  676 389  HOH HOH A . 
W 8 HOH 77  677 634  HOH HOH A . 
W 8 HOH 78  678 595  HOH HOH A . 
W 8 HOH 79  679 590  HOH HOH A . 
W 8 HOH 80  680 391  HOH HOH A . 
W 8 HOH 81  681 889  HOH HOH A . 
W 8 HOH 82  682 967  HOH HOH A . 
W 8 HOH 83  683 44   HOH HOH A . 
W 8 HOH 84  684 379  HOH HOH A . 
W 8 HOH 85  685 207  HOH HOH A . 
W 8 HOH 86  686 725  HOH HOH A . 
W 8 HOH 87  687 221  HOH HOH A . 
W 8 HOH 88  688 462  HOH HOH A . 
W 8 HOH 89  689 673  HOH HOH A . 
W 8 HOH 90  690 25   HOH HOH A . 
W 8 HOH 91  691 828  HOH HOH A . 
W 8 HOH 92  692 142  HOH HOH A . 
W 8 HOH 93  693 51   HOH HOH A . 
W 8 HOH 94  694 168  HOH HOH A . 
W 8 HOH 95  695 178  HOH HOH A . 
W 8 HOH 96  696 205  HOH HOH A . 
W 8 HOH 97  697 903  HOH HOH A . 
W 8 HOH 98  698 164  HOH HOH A . 
W 8 HOH 99  699 688  HOH HOH A . 
W 8 HOH 100 700 216  HOH HOH A . 
W 8 HOH 101 701 40   HOH HOH A . 
W 8 HOH 102 702 58   HOH HOH A . 
W 8 HOH 103 703 510  HOH HOH A . 
W 8 HOH 104 704 490  HOH HOH A . 
W 8 HOH 105 705 852  HOH HOH A . 
W 8 HOH 106 706 695  HOH HOH A . 
W 8 HOH 107 707 204  HOH HOH A . 
W 8 HOH 108 708 3    HOH HOH A . 
W 8 HOH 109 709 45   HOH HOH A . 
W 8 HOH 110 710 122  HOH HOH A . 
W 8 HOH 111 711 174  HOH HOH A . 
W 8 HOH 112 712 607  HOH HOH A . 
W 8 HOH 113 713 371  HOH HOH A . 
W 8 HOH 114 714 447  HOH HOH A . 
W 8 HOH 115 715 39   HOH HOH A . 
W 8 HOH 116 716 83   HOH HOH A . 
W 8 HOH 117 717 255  HOH HOH A . 
W 8 HOH 118 718 738  HOH HOH A . 
W 8 HOH 119 719 497  HOH HOH A . 
W 8 HOH 120 720 851  HOH HOH A . 
W 8 HOH 121 721 258  HOH HOH A . 
W 8 HOH 122 722 401  HOH HOH A . 
W 8 HOH 123 723 469  HOH HOH A . 
W 8 HOH 124 724 135  HOH HOH A . 
W 8 HOH 125 725 150  HOH HOH A . 
W 8 HOH 126 726 583  HOH HOH A . 
W 8 HOH 127 727 232  HOH HOH A . 
W 8 HOH 128 728 119  HOH HOH A . 
W 8 HOH 129 729 10   HOH HOH A . 
W 8 HOH 130 730 220  HOH HOH A . 
W 8 HOH 131 731 97   HOH HOH A . 
W 8 HOH 132 732 206  HOH HOH A . 
W 8 HOH 133 733 67   HOH HOH A . 
W 8 HOH 134 734 84   HOH HOH A . 
W 8 HOH 135 735 925  HOH HOH A . 
W 8 HOH 136 736 133  HOH HOH A . 
W 8 HOH 137 737 120  HOH HOH A . 
W 8 HOH 138 738 334  HOH HOH A . 
W 8 HOH 139 739 431  HOH HOH A . 
W 8 HOH 140 740 347  HOH HOH A . 
W 8 HOH 141 741 12   HOH HOH A . 
W 8 HOH 142 742 609  HOH HOH A . 
W 8 HOH 143 743 662  HOH HOH A . 
W 8 HOH 144 744 355  HOH HOH A . 
W 8 HOH 145 745 7    HOH HOH A . 
W 8 HOH 146 746 908  HOH HOH A . 
W 8 HOH 147 747 481  HOH HOH A . 
W 8 HOH 148 748 43   HOH HOH A . 
W 8 HOH 149 749 17   HOH HOH A . 
W 8 HOH 150 750 991  HOH HOH A . 
W 8 HOH 151 751 363  HOH HOH A . 
W 8 HOH 152 752 49   HOH HOH A . 
W 8 HOH 153 753 702  HOH HOH A . 
W 8 HOH 154 754 235  HOH HOH A . 
W 8 HOH 155 755 711  HOH HOH A . 
W 8 HOH 156 756 54   HOH HOH A . 
W 8 HOH 157 757 82   HOH HOH A . 
W 8 HOH 158 758 75   HOH HOH A . 
W 8 HOH 159 759 118  HOH HOH A . 
W 8 HOH 160 760 26   HOH HOH A . 
W 8 HOH 161 761 413  HOH HOH A . 
W 8 HOH 162 762 101  HOH HOH A . 
W 8 HOH 163 763 163  HOH HOH A . 
W 8 HOH 164 764 706  HOH HOH A . 
W 8 HOH 165 765 572  HOH HOH A . 
W 8 HOH 166 766 219  HOH HOH A . 
W 8 HOH 167 767 380  HOH HOH A . 
W 8 HOH 168 768 210  HOH HOH A . 
W 8 HOH 169 769 557  HOH HOH A . 
W 8 HOH 170 770 265  HOH HOH A . 
W 8 HOH 171 771 18   HOH HOH A . 
W 8 HOH 172 772 293  HOH HOH A . 
W 8 HOH 173 773 927  HOH HOH A . 
W 8 HOH 174 774 95   HOH HOH A . 
W 8 HOH 175 775 1003 HOH HOH A . 
W 8 HOH 176 776 515  HOH HOH A . 
W 8 HOH 177 777 331  HOH HOH A . 
W 8 HOH 178 778 719  HOH HOH A . 
W 8 HOH 179 779 516  HOH HOH A . 
W 8 HOH 180 780 870  HOH HOH A . 
W 8 HOH 181 781 342  HOH HOH A . 
W 8 HOH 182 782 111  HOH HOH A . 
W 8 HOH 183 783 276  HOH HOH A . 
W 8 HOH 184 784 98   HOH HOH A . 
W 8 HOH 185 785 1015 HOH HOH A . 
W 8 HOH 186 786 50   HOH HOH A . 
W 8 HOH 187 787 620  HOH HOH A . 
W 8 HOH 188 788 229  HOH HOH A . 
W 8 HOH 189 789 28   HOH HOH A . 
W 8 HOH 190 790 900  HOH HOH A . 
W 8 HOH 191 791 124  HOH HOH A . 
W 8 HOH 192 792 36   HOH HOH A . 
W 8 HOH 193 793 52   HOH HOH A . 
W 8 HOH 194 794 208  HOH HOH A . 
W 8 HOH 195 795 323  HOH HOH A . 
W 8 HOH 196 796 175  HOH HOH A . 
W 8 HOH 197 797 979  HOH HOH A . 
W 8 HOH 198 798 472  HOH HOH A . 
W 8 HOH 199 799 9    HOH HOH A . 
W 8 HOH 200 800 103  HOH HOH A . 
W 8 HOH 201 801 188  HOH HOH A . 
W 8 HOH 202 802 898  HOH HOH A . 
W 8 HOH 203 803 211  HOH HOH A . 
W 8 HOH 204 804 498  HOH HOH A . 
W 8 HOH 205 805 338  HOH HOH A . 
W 8 HOH 206 806 246  HOH HOH A . 
W 8 HOH 207 807 234  HOH HOH A . 
W 8 HOH 208 808 615  HOH HOH A . 
W 8 HOH 209 809 624  HOH HOH A . 
W 8 HOH 210 810 376  HOH HOH A . 
W 8 HOH 211 811 65   HOH HOH A . 
W 8 HOH 212 812 866  HOH HOH A . 
W 8 HOH 213 813 568  HOH HOH A . 
W 8 HOH 214 814 476  HOH HOH A . 
W 8 HOH 215 815 597  HOH HOH A . 
W 8 HOH 216 816 671  HOH HOH A . 
W 8 HOH 217 817 403  HOH HOH A . 
W 8 HOH 218 818 488  HOH HOH A . 
W 8 HOH 219 819 37   HOH HOH A . 
W 8 HOH 220 820 822  HOH HOH A . 
W 8 HOH 221 821 952  HOH HOH A . 
W 8 HOH 222 822 92   HOH HOH A . 
W 8 HOH 223 823 582  HOH HOH A . 
W 8 HOH 224 824 641  HOH HOH A . 
W 8 HOH 225 825 270  HOH HOH A . 
W 8 HOH 226 826 252  HOH HOH A . 
W 8 HOH 227 827 853  HOH HOH A . 
W 8 HOH 228 828 330  HOH HOH A . 
W 8 HOH 229 829 862  HOH HOH A . 
W 8 HOH 230 830 599  HOH HOH A . 
W 8 HOH 231 831 362  HOH HOH A . 
W 8 HOH 232 832 141  HOH HOH A . 
W 8 HOH 233 833 317  HOH HOH A . 
W 8 HOH 234 834 409  HOH HOH A . 
W 8 HOH 235 835 6    HOH HOH A . 
W 8 HOH 236 836 888  HOH HOH A . 
W 8 HOH 237 837 29   HOH HOH A . 
W 8 HOH 238 838 285  HOH HOH A . 
W 8 HOH 239 839 479  HOH HOH A . 
W 8 HOH 240 840 181  HOH HOH A . 
W 8 HOH 241 841 145  HOH HOH A . 
W 8 HOH 242 842 645  HOH HOH A . 
W 8 HOH 243 843 543  HOH HOH A . 
W 8 HOH 244 844 496  HOH HOH A . 
W 8 HOH 245 845 622  HOH HOH A . 
W 8 HOH 246 846 278  HOH HOH A . 
W 8 HOH 247 847 244  HOH HOH A . 
W 8 HOH 248 848 902  HOH HOH A . 
W 8 HOH 249 849 909  HOH HOH A . 
W 8 HOH 250 850 894  HOH HOH A . 
W 8 HOH 251 851 143  HOH HOH A . 
W 8 HOH 252 852 689  HOH HOH A . 
W 8 HOH 253 853 35   HOH HOH A . 
W 8 HOH 254 854 106  HOH HOH A . 
W 8 HOH 255 855 149  HOH HOH A . 
W 8 HOH 256 856 721  HOH HOH A . 
W 8 HOH 257 857 126  HOH HOH A . 
W 8 HOH 258 858 396  HOH HOH A . 
W 8 HOH 259 859 418  HOH HOH A . 
W 8 HOH 260 860 737  HOH HOH A . 
W 8 HOH 261 861 612  HOH HOH A . 
W 8 HOH 262 862 11   HOH HOH A . 
W 8 HOH 263 863 571  HOH HOH A . 
W 8 HOH 264 864 793  HOH HOH A . 
W 8 HOH 265 865 374  HOH HOH A . 
W 8 HOH 266 866 88   HOH HOH A . 
W 8 HOH 267 867 460  HOH HOH A . 
W 8 HOH 268 868 807  HOH HOH A . 
W 8 HOH 269 869 325  HOH HOH A . 
W 8 HOH 270 870 891  HOH HOH A . 
W 8 HOH 271 871 90   HOH HOH A . 
W 8 HOH 272 872 324  HOH HOH A . 
W 8 HOH 273 873 687  HOH HOH A . 
W 8 HOH 274 874 173  HOH HOH A . 
W 8 HOH 275 875 170  HOH HOH A . 
W 8 HOH 276 876 610  HOH HOH A . 
W 8 HOH 277 877 296  HOH HOH A . 
W 8 HOH 278 878 321  HOH HOH A . 
W 8 HOH 279 879 946  HOH HOH A . 
W 8 HOH 280 880 309  HOH HOH A . 
W 8 HOH 281 881 836  HOH HOH A . 
W 8 HOH 282 882 495  HOH HOH A . 
W 8 HOH 283 883 850  HOH HOH A . 
W 8 HOH 284 884 844  HOH HOH A . 
W 8 HOH 285 885 904  HOH HOH A . 
W 8 HOH 286 886 684  HOH HOH A . 
W 8 HOH 287 887 772  HOH HOH A . 
W 8 HOH 288 888 773  HOH HOH A . 
W 8 HOH 289 889 8    HOH HOH A . 
W 8 HOH 290 890 425  HOH HOH A . 
W 8 HOH 291 891 744  HOH HOH A . 
W 8 HOH 292 892 996  HOH HOH A . 
W 8 HOH 293 893 555  HOH HOH A . 
W 8 HOH 294 894 637  HOH HOH A . 
W 8 HOH 295 895 954  HOH HOH A . 
W 8 HOH 296 896 161  HOH HOH A . 
W 8 HOH 297 897 457  HOH HOH A . 
W 8 HOH 298 898 477  HOH HOH A . 
W 8 HOH 299 899 775  HOH HOH A . 
W 8 HOH 300 900 886  HOH HOH A . 
W 8 HOH 301 901 405  HOH HOH A . 
W 8 HOH 302 902 780  HOH HOH A . 
W 8 HOH 303 903 846  HOH HOH A . 
W 8 HOH 304 904 458  HOH HOH A . 
W 8 HOH 305 905 451  HOH HOH A . 
W 8 HOH 306 906 343  HOH HOH A . 
W 8 HOH 307 907 977  HOH HOH A . 
W 8 HOH 308 908 785  HOH HOH A . 
W 8 HOH 309 909 315  HOH HOH A . 
W 8 HOH 310 910 936  HOH HOH A . 
W 8 HOH 311 911 998  HOH HOH A . 
W 8 HOH 312 912 734  HOH HOH A . 
W 8 HOH 313 913 390  HOH HOH A . 
W 8 HOH 314 914 879  HOH HOH A . 
W 8 HOH 315 915 574  HOH HOH A . 
W 8 HOH 316 916 910  HOH HOH A . 
W 8 HOH 317 917 813  HOH HOH A . 
W 8 HOH 318 918 682  HOH HOH A . 
W 8 HOH 319 919 713  HOH HOH A . 
W 8 HOH 320 920 741  HOH HOH A . 
W 8 HOH 321 921 466  HOH HOH A . 
W 8 HOH 322 922 805  HOH HOH A . 
W 8 HOH 323 923 727  HOH HOH A . 
W 8 HOH 324 924 694  HOH HOH A . 
W 8 HOH 325 925 901  HOH HOH A . 
W 8 HOH 326 926 710  HOH HOH A . 
W 8 HOH 327 927 55   HOH HOH A . 
W 8 HOH 328 928 386  HOH HOH A . 
W 8 HOH 329 929 433  HOH HOH A . 
W 8 HOH 330 930 617  HOH HOH A . 
W 8 HOH 331 931 865  HOH HOH A . 
W 8 HOH 332 932 949  HOH HOH A . 
W 8 HOH 333 933 999  HOH HOH A . 
W 8 HOH 334 934 1017 HOH HOH A . 
W 8 HOH 335 935 677  HOH HOH A . 
W 8 HOH 336 936 357  HOH HOH A . 
W 8 HOH 337 937 801  HOH HOH A . 
W 8 HOH 338 938 335  HOH HOH A . 
W 8 HOH 339 939 786  HOH HOH A . 
W 8 HOH 340 940 654  HOH HOH A . 
W 8 HOH 341 941 798  HOH HOH A . 
W 8 HOH 342 942 628  HOH HOH A . 
W 8 HOH 343 943 539  HOH HOH A . 
W 8 HOH 344 944 556  HOH HOH A . 
W 8 HOH 345 945 531  HOH HOH A . 
W 8 HOH 346 946 926  HOH HOH A . 
W 8 HOH 347 947 370  HOH HOH A . 
W 8 HOH 348 948 890  HOH HOH A . 
W 8 HOH 349 949 613  HOH HOH A . 
W 8 HOH 350 950 352  HOH HOH A . 
W 8 HOH 351 951 787  HOH HOH A . 
W 8 HOH 352 952 797  HOH HOH A . 
W 8 HOH 353 953 341  HOH HOH A . 
W 8 HOH 354 954 420  HOH HOH A . 
W 8 HOH 355 955 1009 HOH HOH A . 
W 8 HOH 356 956 587  HOH HOH A . 
W 8 HOH 357 957 757  HOH HOH A . 
W 8 HOH 358 958 752  HOH HOH A . 
W 8 HOH 359 959 809  HOH HOH A . 
W 8 HOH 360 960 948  HOH HOH A . 
W 8 HOH 361 961 818  HOH HOH A . 
W 8 HOH 362 962 747  HOH HOH A . 
W 8 HOH 363 963 619  HOH HOH A . 
W 8 HOH 364 964 820  HOH HOH A . 
W 8 HOH 365 965 796  HOH HOH A . 
W 8 HOH 366 966 505  HOH HOH A . 
W 8 HOH 367 967 233  HOH HOH A . 
W 8 HOH 368 968 817  HOH HOH A . 
W 8 HOH 369 969 895  HOH HOH A . 
W 8 HOH 370 970 559  HOH HOH A . 
W 8 HOH 371 971 605  HOH HOH A . 
W 8 HOH 372 972 659  HOH HOH A . 
W 8 HOH 373 973 547  HOH HOH A . 
W 8 HOH 374 974 329  HOH HOH A . 
W 8 HOH 375 975 560  HOH HOH A . 
W 8 HOH 376 976 392  HOH HOH A . 
W 8 HOH 377 977 791  HOH HOH A . 
W 8 HOH 378 978 905  HOH HOH A . 
W 8 HOH 379 979 827  HOH HOH A . 
W 8 HOH 380 980 740  HOH HOH A . 
W 8 HOH 381 981 896  HOH HOH A . 
X 8 HOH 1   601 872  HOH HOH B . 
X 8 HOH 2   602 951  HOH HOH B . 
X 8 HOH 3   603 753  HOH HOH B . 
X 8 HOH 4   604 849  HOH HOH B . 
X 8 HOH 5   605 358  HOH HOH B . 
X 8 HOH 6   606 487  HOH HOH B . 
X 8 HOH 7   607 997  HOH HOH B . 
X 8 HOH 8   608 921  HOH HOH B . 
X 8 HOH 9   609 751  HOH HOH B . 
X 8 HOH 10  610 313  HOH HOH B . 
X 8 HOH 11  611 340  HOH HOH B . 
X 8 HOH 12  612 1010 HOH HOH B . 
X 8 HOH 13  613 608  HOH HOH B . 
X 8 HOH 14  614 429  HOH HOH B . 
X 8 HOH 15  615 994  HOH HOH B . 
X 8 HOH 16  616 676  HOH HOH B . 
X 8 HOH 17  617 696  HOH HOH B . 
X 8 HOH 18  618 287  HOH HOH B . 
X 8 HOH 19  619 506  HOH HOH B . 
X 8 HOH 20  620 762  HOH HOH B . 
X 8 HOH 21  621 916  HOH HOH B . 
X 8 HOH 22  622 588  HOH HOH B . 
X 8 HOH 23  623 434  HOH HOH B . 
X 8 HOH 24  624 642  HOH HOH B . 
X 8 HOH 25  625 591  HOH HOH B . 
X 8 HOH 26  626 183  HOH HOH B . 
X 8 HOH 27  627 501  HOH HOH B . 
X 8 HOH 28  628 80   HOH HOH B . 
X 8 HOH 29  629 400  HOH HOH B . 
X 8 HOH 30  630 66   HOH HOH B . 
X 8 HOH 31  631 166  HOH HOH B . 
X 8 HOH 32  632 651  HOH HOH B . 
X 8 HOH 33  633 573  HOH HOH B . 
X 8 HOH 34  634 678  HOH HOH B . 
X 8 HOH 35  635 532  HOH HOH B . 
X 8 HOH 36  636 130  HOH HOH B . 
X 8 HOH 37  637 384  HOH HOH B . 
X 8 HOH 38  638 378  HOH HOH B . 
X 8 HOH 39  639 631  HOH HOH B . 
X 8 HOH 40  640 292  HOH HOH B . 
X 8 HOH 41  641 442  HOH HOH B . 
X 8 HOH 42  642 769  HOH HOH B . 
X 8 HOH 43  643 514  HOH HOH B . 
X 8 HOH 44  644 373  HOH HOH B . 
X 8 HOH 45  645 214  HOH HOH B . 
X 8 HOH 46  646 57   HOH HOH B . 
X 8 HOH 47  647 517  HOH HOH B . 
X 8 HOH 48  648 162  HOH HOH B . 
X 8 HOH 49  649 993  HOH HOH B . 
X 8 HOH 50  650 618  HOH HOH B . 
X 8 HOH 51  651 38   HOH HOH B . 
X 8 HOH 52  652 1016 HOH HOH B . 
X 8 HOH 53  653 511  HOH HOH B . 
X 8 HOH 54  654 527  HOH HOH B . 
X 8 HOH 55  655 463  HOH HOH B . 
X 8 HOH 56  656 192  HOH HOH B . 
X 8 HOH 57  657 271  HOH HOH B . 
X 8 HOH 58  658 388  HOH HOH B . 
X 8 HOH 59  659 197  HOH HOH B . 
X 8 HOH 60  660 679  HOH HOH B . 
X 8 HOH 61  661 453  HOH HOH B . 
X 8 HOH 62  662 91   HOH HOH B . 
X 8 HOH 63  663 521  HOH HOH B . 
X 8 HOH 64  664 428  HOH HOH B . 
X 8 HOH 65  665 774  HOH HOH B . 
X 8 HOH 66  666 71   HOH HOH B . 
X 8 HOH 67  667 519  HOH HOH B . 
X 8 HOH 68  668 732  HOH HOH B . 
X 8 HOH 69  669 249  HOH HOH B . 
X 8 HOH 70  670 722  HOH HOH B . 
X 8 HOH 71  671 289  HOH HOH B . 
X 8 HOH 72  672 34   HOH HOH B . 
X 8 HOH 73  673 606  HOH HOH B . 
X 8 HOH 74  674 522  HOH HOH B . 
X 8 HOH 75  675 584  HOH HOH B . 
X 8 HOH 76  676 303  HOH HOH B . 
X 8 HOH 77  677 653  HOH HOH B . 
X 8 HOH 78  678 113  HOH HOH B . 
X 8 HOH 79  679 81   HOH HOH B . 
X 8 HOH 80  680 172  HOH HOH B . 
X 8 HOH 81  681 64   HOH HOH B . 
X 8 HOH 82  682 387  HOH HOH B . 
X 8 HOH 83  683 102  HOH HOH B . 
X 8 HOH 84  684 300  HOH HOH B . 
X 8 HOH 85  685 53   HOH HOH B . 
X 8 HOH 86  686 223  HOH HOH B . 
X 8 HOH 87  687 1004 HOH HOH B . 
X 8 HOH 88  688 690  HOH HOH B . 
X 8 HOH 89  689 937  HOH HOH B . 
X 8 HOH 90  690 760  HOH HOH B . 
X 8 HOH 91  691 117  HOH HOH B . 
X 8 HOH 92  692 445  HOH HOH B . 
X 8 HOH 93  693 670  HOH HOH B . 
X 8 HOH 94  694 314  HOH HOH B . 
X 8 HOH 95  695 530  HOH HOH B . 
X 8 HOH 96  696 42   HOH HOH B . 
X 8 HOH 97  697 304  HOH HOH B . 
X 8 HOH 98  698 23   HOH HOH B . 
X 8 HOH 99  699 215  HOH HOH B . 
X 8 HOH 100 700 156  HOH HOH B . 
X 8 HOH 101 701 94   HOH HOH B . 
X 8 HOH 102 702 199  HOH HOH B . 
X 8 HOH 103 703 755  HOH HOH B . 
X 8 HOH 104 704 546  HOH HOH B . 
X 8 HOH 105 705 758  HOH HOH B . 
X 8 HOH 106 706 600  HOH HOH B . 
X 8 HOH 107 707 96   HOH HOH B . 
X 8 HOH 108 708 502  HOH HOH B . 
X 8 HOH 109 709 159  HOH HOH B . 
X 8 HOH 110 710 60   HOH HOH B . 
X 8 HOH 111 711 228  HOH HOH B . 
X 8 HOH 112 712 985  HOH HOH B . 
X 8 HOH 113 713 152  HOH HOH B . 
X 8 HOH 114 714 980  HOH HOH B . 
X 8 HOH 115 715 664  HOH HOH B . 
X 8 HOH 116 716 31   HOH HOH B . 
X 8 HOH 117 717 328  HOH HOH B . 
X 8 HOH 118 718 78   HOH HOH B . 
X 8 HOH 119 719 132  HOH HOH B . 
X 8 HOH 120 720 107  HOH HOH B . 
X 8 HOH 121 721 76   HOH HOH B . 
X 8 HOH 122 722 761  HOH HOH B . 
X 8 HOH 123 723 545  HOH HOH B . 
X 8 HOH 124 724 27   HOH HOH B . 
X 8 HOH 125 725 847  HOH HOH B . 
X 8 HOH 126 726 525  HOH HOH B . 
X 8 HOH 127 727 336  HOH HOH B . 
X 8 HOH 128 728 349  HOH HOH B . 
X 8 HOH 129 729 200  HOH HOH B . 
X 8 HOH 130 730 784  HOH HOH B . 
X 8 HOH 131 731 14   HOH HOH B . 
X 8 HOH 132 732 368  HOH HOH B . 
X 8 HOH 133 733 282  HOH HOH B . 
X 8 HOH 134 734 332  HOH HOH B . 
X 8 HOH 135 735 212  HOH HOH B . 
X 8 HOH 136 736 284  HOH HOH B . 
X 8 HOH 137 737 157  HOH HOH B . 
X 8 HOH 138 738 274  HOH HOH B . 
X 8 HOH 139 739 354  HOH HOH B . 
X 8 HOH 140 740 364  HOH HOH B . 
X 8 HOH 141 741 257  HOH HOH B . 
X 8 HOH 142 742 177  HOH HOH B . 
X 8 HOH 143 743 742  HOH HOH B . 
X 8 HOH 144 744 268  HOH HOH B . 
X 8 HOH 145 745 576  HOH HOH B . 
X 8 HOH 146 746 288  HOH HOH B . 
X 8 HOH 147 747 563  HOH HOH B . 
X 8 HOH 148 748 179  HOH HOH B . 
X 8 HOH 149 749 726  HOH HOH B . 
X 8 HOH 150 750 158  HOH HOH B . 
X 8 HOH 151 751 356  HOH HOH B . 
X 8 HOH 152 752 176  HOH HOH B . 
X 8 HOH 153 753 191  HOH HOH B . 
X 8 HOH 154 754 2    HOH HOH B . 
X 8 HOH 155 755 281  HOH HOH B . 
X 8 HOH 156 756 397  HOH HOH B . 
X 8 HOH 157 757 153  HOH HOH B . 
X 8 HOH 158 758 707  HOH HOH B . 
X 8 HOH 159 759 225  HOH HOH B . 
X 8 HOH 160 760 394  HOH HOH B . 
X 8 HOH 161 761 16   HOH HOH B . 
X 8 HOH 162 762 144  HOH HOH B . 
X 8 HOH 163 763 767  HOH HOH B . 
X 8 HOH 164 764 125  HOH HOH B . 
X 8 HOH 165 765 1011 HOH HOH B . 
X 8 HOH 166 766 277  HOH HOH B . 
X 8 HOH 167 767 5    HOH HOH B . 
X 8 HOH 168 768 108  HOH HOH B . 
X 8 HOH 169 769 4    HOH HOH B . 
X 8 HOH 170 770 513  HOH HOH B . 
X 8 HOH 171 771 165  HOH HOH B . 
X 8 HOH 172 772 764  HOH HOH B . 
X 8 HOH 173 773 861  HOH HOH B . 
X 8 HOH 174 774 452  HOH HOH B . 
X 8 HOH 175 775 222  HOH HOH B . 
X 8 HOH 176 776 312  HOH HOH B . 
X 8 HOH 177 777 248  HOH HOH B . 
X 8 HOH 178 778 594  HOH HOH B . 
X 8 HOH 179 779 646  HOH HOH B . 
X 8 HOH 180 780 79   HOH HOH B . 
X 8 HOH 181 781 89   HOH HOH B . 
X 8 HOH 182 782 585  HOH HOH B . 
X 8 HOH 183 783 421  HOH HOH B . 
X 8 HOH 184 784 579  HOH HOH B . 
X 8 HOH 185 785 351  HOH HOH B . 
X 8 HOH 186 786 698  HOH HOH B . 
X 8 HOH 187 787 105  HOH HOH B . 
X 8 HOH 188 788 109  HOH HOH B . 
X 8 HOH 189 789 863  HOH HOH B . 
X 8 HOH 190 790 685  HOH HOH B . 
X 8 HOH 191 791 260  HOH HOH B . 
X 8 HOH 192 792 339  HOH HOH B . 
X 8 HOH 193 793 990  HOH HOH B . 
X 8 HOH 194 794 731  HOH HOH B . 
X 8 HOH 195 795 467  HOH HOH B . 
X 8 HOH 196 796 316  HOH HOH B . 
X 8 HOH 197 797 565  HOH HOH B . 
X 8 HOH 198 798 959  HOH HOH B . 
X 8 HOH 199 799 147  HOH HOH B . 
X 8 HOH 200 800 728  HOH HOH B . 
X 8 HOH 201 801 621  HOH HOH B . 
X 8 HOH 202 802 482  HOH HOH B . 
X 8 HOH 203 803 636  HOH HOH B . 
X 8 HOH 204 804 290  HOH HOH B . 
X 8 HOH 205 805 912  HOH HOH B . 
X 8 HOH 206 806 275  HOH HOH B . 
X 8 HOH 207 807 272  HOH HOH B . 
X 8 HOH 208 808 311  HOH HOH B . 
X 8 HOH 209 809 538  HOH HOH B . 
X 8 HOH 210 810 643  HOH HOH B . 
X 8 HOH 211 811 598  HOH HOH B . 
X 8 HOH 212 812 266  HOH HOH B . 
X 8 HOH 213 813 657  HOH HOH B . 
X 8 HOH 214 814 68   HOH HOH B . 
X 8 HOH 215 815 432  HOH HOH B . 
X 8 HOH 216 816 614  HOH HOH B . 
X 8 HOH 217 817 372  HOH HOH B . 
X 8 HOH 218 818 406  HOH HOH B . 
X 8 HOH 219 819 518  HOH HOH B . 
X 8 HOH 220 820 131  HOH HOH B . 
X 8 HOH 221 821 134  HOH HOH B . 
X 8 HOH 222 822 224  HOH HOH B . 
X 8 HOH 223 823 459  HOH HOH B . 
X 8 HOH 224 824 776  HOH HOH B . 
X 8 HOH 225 825 439  HOH HOH B . 
X 8 HOH 226 826 749  HOH HOH B . 
X 8 HOH 227 827 399  HOH HOH B . 
X 8 HOH 228 828 875  HOH HOH B . 
X 8 HOH 229 829 375  HOH HOH B . 
X 8 HOH 230 830 1012 HOH HOH B . 
X 8 HOH 231 831 243  HOH HOH B . 
X 8 HOH 232 832 867  HOH HOH B . 
X 8 HOH 233 833 500  HOH HOH B . 
X 8 HOH 234 834 639  HOH HOH B . 
X 8 HOH 235 835 253  HOH HOH B . 
X 8 HOH 236 836 19   HOH HOH B . 
X 8 HOH 237 837 804  HOH HOH B . 
X 8 HOH 238 838 112  HOH HOH B . 
X 8 HOH 239 839 140  HOH HOH B . 
X 8 HOH 240 840 911  HOH HOH B . 
X 8 HOH 241 841 693  HOH HOH B . 
X 8 HOH 242 842 186  HOH HOH B . 
X 8 HOH 243 843 788  HOH HOH B . 
X 8 HOH 244 844 724  HOH HOH B . 
X 8 HOH 245 845 524  HOH HOH B . 
X 8 HOH 246 846 361  HOH HOH B . 
X 8 HOH 247 847 966  HOH HOH B . 
X 8 HOH 248 848 327  HOH HOH B . 
X 8 HOH 249 849 856  HOH HOH B . 
X 8 HOH 250 850 412  HOH HOH B . 
X 8 HOH 251 851 69   HOH HOH B . 
X 8 HOH 252 852 580  HOH HOH B . 
X 8 HOH 253 853 440  HOH HOH B . 
X 8 HOH 254 854 819  HOH HOH B . 
X 8 HOH 255 855 280  HOH HOH B . 
X 8 HOH 256 856 448  HOH HOH B . 
X 8 HOH 257 857 182  HOH HOH B . 
X 8 HOH 258 858 526  HOH HOH B . 
X 8 HOH 259 859 148  HOH HOH B . 
X 8 HOH 260 860 848  HOH HOH B . 
X 8 HOH 261 861 842  HOH HOH B . 
X 8 HOH 262 862 115  HOH HOH B . 
X 8 HOH 263 863 860  HOH HOH B . 
X 8 HOH 264 864 99   HOH HOH B . 
X 8 HOH 265 865 436  HOH HOH B . 
X 8 HOH 266 866 869  HOH HOH B . 
X 8 HOH 267 867 602  HOH HOH B . 
X 8 HOH 268 868 841  HOH HOH B . 
X 8 HOH 269 869 783  HOH HOH B . 
X 8 HOH 270 870 976  HOH HOH B . 
X 8 HOH 271 871 369  HOH HOH B . 
X 8 HOH 272 872 733  HOH HOH B . 
X 8 HOH 273 873 703  HOH HOH B . 
X 8 HOH 274 874 887  HOH HOH B . 
X 8 HOH 275 875 778  HOH HOH B . 
X 8 HOH 276 876 763  HOH HOH B . 
X 8 HOH 277 877 803  HOH HOH B . 
X 8 HOH 278 878 302  HOH HOH B . 
X 8 HOH 279 879 983  HOH HOH B . 
X 8 HOH 280 880 718  HOH HOH B . 
X 8 HOH 281 881 310  HOH HOH B . 
X 8 HOH 282 882 717  HOH HOH B . 
X 8 HOH 283 883 802  HOH HOH B . 
X 8 HOH 284 884 825  HOH HOH B . 
X 8 HOH 285 885 816  HOH HOH B . 
X 8 HOH 286 886 666  HOH HOH B . 
X 8 HOH 287 887 675  HOH HOH B . 
X 8 HOH 288 888 883  HOH HOH B . 
X 8 HOH 289 889 672  HOH HOH B . 
X 8 HOH 290 890 1013 HOH HOH B . 
X 8 HOH 291 891 348  HOH HOH B . 
X 8 HOH 292 892 958  HOH HOH B . 
X 8 HOH 293 893 474  HOH HOH B . 
X 8 HOH 294 894 596  HOH HOH B . 
X 8 HOH 295 895 934  HOH HOH B . 
X 8 HOH 296 896 907  HOH HOH B . 
X 8 HOH 297 897 333  HOH HOH B . 
X 8 HOH 298 898 878  HOH HOH B . 
X 8 HOH 299 899 789  HOH HOH B . 
X 8 HOH 300 900 395  HOH HOH B . 
X 8 HOH 301 901 765  HOH HOH B . 
X 8 HOH 302 902 833  HOH HOH B . 
X 8 HOH 303 903 929  HOH HOH B . 
X 8 HOH 304 904 1005 HOH HOH B . 
X 8 HOH 305 905 383  HOH HOH B . 
X 8 HOH 306 906 913  HOH HOH B . 
X 8 HOH 307 907 616  HOH HOH B . 
X 8 HOH 308 908 829  HOH HOH B . 
X 8 HOH 309 909 928  HOH HOH B . 
X 8 HOH 310 910 564  HOH HOH B . 
X 8 HOH 311 911 930  HOH HOH B . 
X 8 HOH 312 912 812  HOH HOH B . 
X 8 HOH 313 913 914  HOH HOH B . 
X 8 HOH 314 914 1000 HOH HOH B . 
X 8 HOH 315 915 931  HOH HOH B . 
X 8 HOH 316 916 360  HOH HOH B . 
X 8 HOH 317 917 840  HOH HOH B . 
X 8 HOH 318 918 933  HOH HOH B . 
X 8 HOH 319 919 194  HOH HOH B . 
X 8 HOH 320 920 231  HOH HOH B . 
X 8 HOH 321 921 320  HOH HOH B . 
X 8 HOH 322 922 794  HOH HOH B . 
X 8 HOH 323 923 982  HOH HOH B . 
X 8 HOH 324 924 455  HOH HOH B . 
X 8 HOH 325 925 839  HOH HOH B . 
X 8 HOH 326 926 552  HOH HOH B . 
X 8 HOH 327 927 885  HOH HOH B . 
X 8 HOH 328 928 644  HOH HOH B . 
X 8 HOH 329 929 831  HOH HOH B . 
X 8 HOH 330 930 1006 HOH HOH B . 
X 8 HOH 331 931 716  HOH HOH B . 
X 8 HOH 332 932 656  HOH HOH B . 
X 8 HOH 333 933 830  HOH HOH B . 
X 8 HOH 334 934 712  HOH HOH B . 
X 8 HOH 335 935 648  HOH HOH B . 
X 8 HOH 336 936 535  HOH HOH B . 
X 8 HOH 337 937 603  HOH HOH B . 
X 8 HOH 338 938 782  HOH HOH B . 
X 8 HOH 339 939 593  HOH HOH B . 
X 8 HOH 340 940 932  HOH HOH B . 
X 8 HOH 341 941 995  HOH HOH B . 
X 8 HOH 342 942 478  HOH HOH B . 
X 8 HOH 343 943 880  HOH HOH B . 
X 8 HOH 344 944 647  HOH HOH B . 
X 8 HOH 345 945 604  HOH HOH B . 
X 8 HOH 346 946 906  HOH HOH B . 
X 8 HOH 347 947 1001 HOH HOH B . 
X 8 HOH 348 948 837  HOH HOH B . 
X 8 HOH 349 949 567  HOH HOH B . 
X 8 HOH 350 950 566  HOH HOH B . 
X 8 HOH 351 951 808  HOH HOH B . 
X 8 HOH 352 952 824  HOH HOH B . 
Y 8 HOH 1   601 468  HOH HOH C . 
Y 8 HOH 2   602 858  HOH HOH C . 
Y 8 HOH 3   603 398  HOH HOH C . 
Y 8 HOH 4   604 660  HOH HOH C . 
Y 8 HOH 5   605 393  HOH HOH C . 
Y 8 HOH 6   606 611  HOH HOH C . 
Y 8 HOH 7   607 414  HOH HOH C . 
Y 8 HOH 8   608 964  HOH HOH C . 
Y 8 HOH 9   609 322  HOH HOH C . 
Y 8 HOH 10  610 407  HOH HOH C . 
Y 8 HOH 11  611 404  HOH HOH C . 
Y 8 HOH 12  612 85   HOH HOH C . 
Y 8 HOH 13  613 633  HOH HOH C . 
Y 8 HOH 14  614 306  HOH HOH C . 
Y 8 HOH 15  615 441  HOH HOH C . 
Y 8 HOH 16  616 422  HOH HOH C . 
Y 8 HOH 17  617 365  HOH HOH C . 
Y 8 HOH 18  618 269  HOH HOH C . 
Y 8 HOH 19  619 551  HOH HOH C . 
Y 8 HOH 20  620 945  HOH HOH C . 
Y 8 HOH 21  621 871  HOH HOH C . 
Y 8 HOH 22  622 701  HOH HOH C . 
Y 8 HOH 23  623 569  HOH HOH C . 
Y 8 HOH 24  624 640  HOH HOH C . 
Y 8 HOH 25  625 963  HOH HOH C . 
Y 8 HOH 26  626 970  HOH HOH C . 
Y 8 HOH 27  627 128  HOH HOH C . 
Y 8 HOH 28  628 123  HOH HOH C . 
Y 8 HOH 29  629 359  HOH HOH C . 
Y 8 HOH 30  630 169  HOH HOH C . 
Y 8 HOH 31  631 897  HOH HOH C . 
Y 8 HOH 32  632 743  HOH HOH C . 
Y 8 HOH 33  633 408  HOH HOH C . 
Y 8 HOH 34  634 638  HOH HOH C . 
Y 8 HOH 35  635 592  HOH HOH C . 
Y 8 HOH 36  636 578  HOH HOH C . 
Y 8 HOH 37  637 77   HOH HOH C . 
Y 8 HOH 38  638 924  HOH HOH C . 
Y 8 HOH 39  639 56   HOH HOH C . 
Y 8 HOH 40  640 86   HOH HOH C . 
Y 8 HOH 41  641 730  HOH HOH C . 
Y 8 HOH 42  642 366  HOH HOH C . 
Y 8 HOH 43  643 623  HOH HOH C . 
Y 8 HOH 44  644 558  HOH HOH C . 
Y 8 HOH 45  645 437  HOH HOH C . 
Y 8 HOH 46  646 708  HOH HOH C . 
Y 8 HOH 47  647 854  HOH HOH C . 
Y 8 HOH 48  648 213  HOH HOH C . 
Y 8 HOH 49  649 754  HOH HOH C . 
Y 8 HOH 50  650 456  HOH HOH C . 
Y 8 HOH 51  651 160  HOH HOH C . 
Y 8 HOH 52  652 279  HOH HOH C . 
Y 8 HOH 53  653 989  HOH HOH C . 
Y 8 HOH 54  654 59   HOH HOH C . 
Y 8 HOH 55  655 167  HOH HOH C . 
Y 8 HOH 56  656 301  HOH HOH C . 
Y 8 HOH 57  657 1007 HOH HOH C . 
Y 8 HOH 58  658 184  HOH HOH C . 
Y 8 HOH 59  659 528  HOH HOH C . 
Y 8 HOH 60  660 259  HOH HOH C . 
Y 8 HOH 61  661 800  HOH HOH C . 
Y 8 HOH 62  662 674  HOH HOH C . 
Y 8 HOH 63  663 454  HOH HOH C . 
Y 8 HOH 64  664 402  HOH HOH C . 
Y 8 HOH 65  665 586  HOH HOH C . 
Y 8 HOH 66  666 41   HOH HOH C . 
Y 8 HOH 67  667 426  HOH HOH C . 
Y 8 HOH 68  668 227  HOH HOH C . 
Y 8 HOH 69  669 121  HOH HOH C . 
Y 8 HOH 70  670 680  HOH HOH C . 
Y 8 HOH 71  671 195  HOH HOH C . 
Y 8 HOH 72  672 882  HOH HOH C . 
Y 8 HOH 73  673 48   HOH HOH C . 
Y 8 HOH 74  674 484  HOH HOH C . 
Y 8 HOH 75  675 180  HOH HOH C . 
Y 8 HOH 76  676 446  HOH HOH C . 
Y 8 HOH 77  677 319  HOH HOH C . 
Y 8 HOH 78  678 424  HOH HOH C . 
Y 8 HOH 79  679 382  HOH HOH C . 
Y 8 HOH 80  680 874  HOH HOH C . 
Y 8 HOH 81  681 129  HOH HOH C . 
Y 8 HOH 82  682 873  HOH HOH C . 
Y 8 HOH 83  683 20   HOH HOH C . 
Y 8 HOH 84  684 187  HOH HOH C . 
Y 8 HOH 85  685 746  HOH HOH C . 
Y 8 HOH 86  686 295  HOH HOH C . 
Y 8 HOH 87  687 345  HOH HOH C . 
Y 8 HOH 88  688 30   HOH HOH C . 
Y 8 HOH 89  689 736  HOH HOH C . 
Y 8 HOH 90  690 957  HOH HOH C . 
Y 8 HOH 91  691 550  HOH HOH C . 
Y 8 HOH 92  692 589  HOH HOH C . 
Y 8 HOH 93  693 435  HOH HOH C . 
Y 8 HOH 94  694 529  HOH HOH C . 
Y 8 HOH 95  695 536  HOH HOH C . 
Y 8 HOH 96  696 770  HOH HOH C . 
Y 8 HOH 97  697 267  HOH HOH C . 
Y 8 HOH 98  698 237  HOH HOH C . 
Y 8 HOH 99  699 110  HOH HOH C . 
Y 8 HOH 100 700 766  HOH HOH C . 
Y 8 HOH 101 701 63   HOH HOH C . 
Y 8 HOH 102 702 245  HOH HOH C . 
Y 8 HOH 103 703 920  HOH HOH C . 
Y 8 HOH 104 704 438  HOH HOH C . 
Y 8 HOH 105 705 723  HOH HOH C . 
Y 8 HOH 106 706 136  HOH HOH C . 
Y 8 HOH 107 707 953  HOH HOH C . 
Y 8 HOH 108 708 226  HOH HOH C . 
Y 8 HOH 109 709 189  HOH HOH C . 
Y 8 HOH 110 710 705  HOH HOH C . 
Y 8 HOH 111 711 346  HOH HOH C . 
Y 8 HOH 112 712 799  HOH HOH C . 
Y 8 HOH 113 713 283  HOH HOH C . 
Y 8 HOH 114 714 70   HOH HOH C . 
Y 8 HOH 115 715 73   HOH HOH C . 
Y 8 HOH 116 716 489  HOH HOH C . 
Y 8 HOH 117 717 410  HOH HOH C . 
Y 8 HOH 118 718 561  HOH HOH C . 
Y 8 HOH 119 719 493  HOH HOH C . 
Y 8 HOH 120 720 416  HOH HOH C . 
Y 8 HOH 121 721 540  HOH HOH C . 
Y 8 HOH 122 722 720  HOH HOH C . 
Y 8 HOH 123 723 464  HOH HOH C . 
Y 8 HOH 124 724 264  HOH HOH C . 
Y 8 HOH 125 725 756  HOH HOH C . 
Y 8 HOH 126 726 570  HOH HOH C . 
Y 8 HOH 127 727 21   HOH HOH C . 
Y 8 HOH 128 728 492  HOH HOH C . 
Y 8 HOH 129 729 692  HOH HOH C . 
Y 8 HOH 130 730 230  HOH HOH C . 
Y 8 HOH 131 731 575  HOH HOH C . 
Y 8 HOH 132 732 367  HOH HOH C . 
Y 8 HOH 133 733 411  HOH HOH C . 
Y 8 HOH 134 734 415  HOH HOH C . 
Y 8 HOH 135 735 273  HOH HOH C . 
Y 8 HOH 136 736 72   HOH HOH C . 
Y 8 HOH 137 737 185  HOH HOH C . 
Y 8 HOH 138 738 968  HOH HOH C . 
Y 8 HOH 139 739 155  HOH HOH C . 
Y 8 HOH 140 740 485  HOH HOH C . 
Y 8 HOH 141 741 735  HOH HOH C . 
Y 8 HOH 142 742 759  HOH HOH C . 
Y 8 HOH 143 743 217  HOH HOH C . 
Y 8 HOH 144 744 935  HOH HOH C . 
Y 8 HOH 145 745 473  HOH HOH C . 
Y 8 HOH 146 746 1    HOH HOH C . 
Y 8 HOH 147 747 669  HOH HOH C . 
Y 8 HOH 148 748 899  HOH HOH C . 
Y 8 HOH 149 749 627  HOH HOH C . 
Y 8 HOH 150 750 263  HOH HOH C . 
Y 8 HOH 151 751 344  HOH HOH C . 
Y 8 HOH 152 752 649  HOH HOH C . 
Y 8 HOH 153 753 483  HOH HOH C . 
Y 8 HOH 154 754 417  HOH HOH C . 
Y 8 HOH 155 755 294  HOH HOH C . 
Y 8 HOH 156 756 471  HOH HOH C . 
Y 8 HOH 157 757 104  HOH HOH C . 
Y 8 HOH 158 758 449  HOH HOH C . 
Y 8 HOH 159 759 549  HOH HOH C . 
Y 8 HOH 160 760 835  HOH HOH C . 
Y 8 HOH 161 761 941  HOH HOH C . 
Y 8 HOH 162 762 845  HOH HOH C . 
Y 8 HOH 163 763 512  HOH HOH C . 
Y 8 HOH 164 764 381  HOH HOH C . 
Y 8 HOH 165 765 917  HOH HOH C . 
Y 8 HOH 166 766 745  HOH HOH C . 
Y 8 HOH 167 767 975  HOH HOH C . 
Y 8 HOH 168 768 942  HOH HOH C . 
Y 8 HOH 169 769 74   HOH HOH C . 
Y 8 HOH 170 770 655  HOH HOH C . 
Y 8 HOH 171 771 541  HOH HOH C . 
Y 8 HOH 172 772 151  HOH HOH C . 
Y 8 HOH 173 773 238  HOH HOH C . 
Y 8 HOH 174 774 1008 HOH HOH C . 
Y 8 HOH 175 775 632  HOH HOH C . 
Y 8 HOH 176 776 201  HOH HOH C . 
Y 8 HOH 177 777 385  HOH HOH C . 
Y 8 HOH 178 778 748  HOH HOH C . 
Y 8 HOH 179 779 533  HOH HOH C . 
Y 8 HOH 180 780 795  HOH HOH C . 
Y 8 HOH 181 781 450  HOH HOH C . 
Y 8 HOH 182 782 939  HOH HOH C . 
Y 8 HOH 183 783 868  HOH HOH C . 
Y 8 HOH 184 784 537  HOH HOH C . 
Y 8 HOH 185 785 475  HOH HOH C . 
Y 8 HOH 186 786 955  HOH HOH C . 
Y 8 HOH 187 787 198  HOH HOH C . 
Y 8 HOH 188 788 947  HOH HOH C . 
Y 8 HOH 189 789 190  HOH HOH C . 
Y 8 HOH 190 790 884  HOH HOH C . 
Y 8 HOH 191 791 961  HOH HOH C . 
Y 8 HOH 192 792 138  HOH HOH C . 
Y 8 HOH 193 793 973  HOH HOH C . 
Y 8 HOH 194 794 635  HOH HOH C . 
Y 8 HOH 195 795 461  HOH HOH C . 
Y 8 HOH 196 796 974  HOH HOH C . 
Y 8 HOH 197 797 777  HOH HOH C . 
Y 8 HOH 198 798 326  HOH HOH C . 
Y 8 HOH 199 799 626  HOH HOH C . 
Y 8 HOH 200 800 202  HOH HOH C . 
Y 8 HOH 201 801 729  HOH HOH C . 
Y 8 HOH 202 802 815  HOH HOH C . 
Y 8 HOH 203 803 24   HOH HOH C . 
Y 8 HOH 204 804 969  HOH HOH C . 
Y 8 HOH 205 805 625  HOH HOH C . 
Y 8 HOH 206 806 46   HOH HOH C . 
Y 8 HOH 207 807 667  HOH HOH C . 
Y 8 HOH 208 808 544  HOH HOH C . 
Y 8 HOH 209 809 507  HOH HOH C . 
Y 8 HOH 210 810 444  HOH HOH C . 
Y 8 HOH 211 811 714  HOH HOH C . 
Y 8 HOH 212 812 950  HOH HOH C . 
Y 8 HOH 213 813 956  HOH HOH C . 
Y 8 HOH 214 814 137  HOH HOH C . 
Y 8 HOH 215 815 15   HOH HOH C . 
Y 8 HOH 216 816 650  HOH HOH C . 
Y 8 HOH 217 817 523  HOH HOH C . 
Y 8 HOH 218 818 700  HOH HOH C . 
Y 8 HOH 219 819 305  HOH HOH C . 
Y 8 HOH 220 820 823  HOH HOH C . 
Y 8 HOH 221 821 261  HOH HOH C . 
Y 8 HOH 222 822 834  HOH HOH C . 
Y 8 HOH 223 823 250  HOH HOH C . 
Y 8 HOH 224 824 876  HOH HOH C . 
Y 8 HOH 225 825 790  HOH HOH C . 
Y 8 HOH 226 826 715  HOH HOH C . 
Y 8 HOH 227 827 915  HOH HOH C . 
Y 8 HOH 228 828 577  HOH HOH C . 
Y 8 HOH 229 829 100  HOH HOH C . 
Y 8 HOH 230 830 548  HOH HOH C . 
Y 8 HOH 231 831 962  HOH HOH C . 
Y 8 HOH 232 832 242  HOH HOH C . 
Y 8 HOH 233 833 491  HOH HOH C . 
Y 8 HOH 234 834 781  HOH HOH C . 
Y 8 HOH 235 835 944  HOH HOH C . 
Y 8 HOH 236 836 307  HOH HOH C . 
Y 8 HOH 237 837 843  HOH HOH C . 
Y 8 HOH 238 838 792  HOH HOH C . 
Y 8 HOH 239 839 601  HOH HOH C . 
Y 8 HOH 240 840 668  HOH HOH C . 
Y 8 HOH 241 841 93   HOH HOH C . 
Y 8 HOH 242 842 427  HOH HOH C . 
Y 8 HOH 243 843 922  HOH HOH C . 
Y 8 HOH 244 844 972  HOH HOH C . 
Y 8 HOH 245 845 318  HOH HOH C . 
Y 8 HOH 246 846 810  HOH HOH C . 
Y 8 HOH 247 847 504  HOH HOH C . 
Y 8 HOH 248 848 534  HOH HOH C . 
Y 8 HOH 249 849 923  HOH HOH C . 
Y 8 HOH 250 850 814  HOH HOH C . 
Y 8 HOH 251 851 750  HOH HOH C . 
Y 8 HOH 252 852 938  HOH HOH C . 
Y 8 HOH 253 853 978  HOH HOH C . 
Y 8 HOH 254 854 986  HOH HOH C . 
Y 8 HOH 255 855 832  HOH HOH C . 
Y 8 HOH 256 856 821  HOH HOH C . 
Y 8 HOH 257 857 553  HOH HOH C . 
Y 8 HOH 258 858 779  HOH HOH C . 
Y 8 HOH 259 859 768  HOH HOH C . 
Y 8 HOH 260 860 965  HOH HOH C . 
Y 8 HOH 261 861 377  HOH HOH C . 
Y 8 HOH 262 862 811  HOH HOH C . 
Y 8 HOH 263 863 981  HOH HOH C . 
Y 8 HOH 264 864 658  HOH HOH C . 
Y 8 HOH 265 865 943  HOH HOH C . 
Y 8 HOH 266 866 419  HOH HOH C . 
Y 8 HOH 267 867 984  HOH HOH C . 
Y 8 HOH 268 868 918  HOH HOH C . 
Y 8 HOH 269 869 480  HOH HOH C . 
Y 8 HOH 270 870 987  HOH HOH C . 
Y 8 HOH 271 871 988  HOH HOH C . 
Y 8 HOH 272 872 919  HOH HOH C . 
Y 8 HOH 273 873 652  HOH HOH C . 
Y 8 HOH 274 874 826  HOH HOH C . 
Y 8 HOH 275 875 542  HOH HOH C . 
Y 8 HOH 276 876 236  HOH HOH C . 
Y 8 HOH 277 877 806  HOH HOH C . 
Y 8 HOH 278 878 1002 HOH HOH C . 
Y 8 HOH 279 879 630  HOH HOH C . 
Y 8 HOH 280 880 486  HOH HOH C . 
Y 8 HOH 281 881 838  HOH HOH C . 
Y 8 HOH 282 882 971  HOH HOH C . 
Y 8 HOH 283 883 430  HOH HOH C . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX ? ? ? '(1.20.1_4487: ???)' 1 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? XDS    ? ? ? .                    2 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS    ? ? ? .                    3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER ? ? ? .                    4 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8W1K 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     158.905 
_cell.length_a_esd                 ? 
_cell.length_b                     170.367 
_cell.length_b_esd                 ? 
_cell.length_c                     121.603 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        24 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8W1K 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                20 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'C 2 2 21' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8W1K 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.78 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          55.71 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    
;30 % (w/v) PEG4000, 0.2 M MgCl2 and 0.1 M Hepes pH 7.5. The protein was concentrated in Buffer GF containing HEPES, NaCl, 1 mM oleic acid, and 5% Glycerol.
;
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            291 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS PILATUS 2M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2021-05-27 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.9772 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'LNLS SIRIUS BEAMLINE MANACA' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.9772 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   MANACA 
_diffrn_source.pdbx_synchrotron_site       'LNLS SIRIUS' 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       8W1K 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              1.7 
_reflns.d_resolution_low                               49.74 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     179979 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           79.3 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                13.55 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          4.02 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                0.153 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.991 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.116 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
loop_
_reflns_shell.d_res_high 
_reflns_shell.d_res_low 
_reflns_shell.meanI_over_sigI_all 
_reflns_shell.meanI_over_sigI_obs 
_reflns_shell.number_measured_all 
_reflns_shell.number_measured_obs 
_reflns_shell.number_possible 
_reflns_shell.number_unique_all 
_reflns_shell.number_unique_obs 
_reflns_shell.percent_possible_obs 
_reflns_shell.Rmerge_F_all 
_reflns_shell.Rmerge_F_obs 
_reflns_shell.meanI_over_sigI_gt 
_reflns_shell.meanI_over_uI_all 
_reflns_shell.meanI_over_uI_gt 
_reflns_shell.number_measured_gt 
_reflns_shell.number_unique_gt 
_reflns_shell.percent_possible_gt 
_reflns_shell.Rmerge_F_gt 
_reflns_shell.Rmerge_I_gt 
_reflns_shell.pdbx_redundancy 
_reflns_shell.pdbx_chi_squared 
_reflns_shell.pdbx_netI_over_sigmaI_all 
_reflns_shell.pdbx_netI_over_sigmaI_obs 
_reflns_shell.pdbx_Rrim_I_all 
_reflns_shell.pdbx_Rpim_I_all 
_reflns_shell.pdbx_rejects 
_reflns_shell.pdbx_ordinal 
_reflns_shell.pdbx_diffrn_id 
_reflns_shell.pdbx_CC_half 
_reflns_shell.pdbx_CC_star 
_reflns_shell.pdbx_R_split 
_reflns_shell.percent_possible_all 
_reflns_shell.Rmerge_I_all 
_reflns_shell.Rmerge_I_obs 
_reflns_shell.pdbx_Rsym_value 
_reflns_shell.pdbx_percent_possible_ellipsoidal 
_reflns_shell.pdbx_percent_possible_spherical 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous 
_reflns_shell.pdbx_percent_possible_spherical_anomalous 
_reflns_shell.pdbx_redundancy_anomalous 
_reflns_shell.pdbx_CC_half_anomalous 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous 
_reflns_shell.pdbx_percent_possible_anomalous 
1.70 1.8   ? ? ? ? ? ? 24273 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 1.399 ? ? 1 1 0.26  ? ? ? ? 1.016 ? ? ? ? ? ? ? ? ? 
1.80 1.93  ? ? ? ? ? ? 22946 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 0.857 ? ? 2 1 0.481 ? ? ? ? 0.626 ? ? ? ? ? ? ? ? ? 
1.93 2.08  ? ? ? ? ? ? 20928 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 0.495 ? ? 3 1 0.75  ? ? ? ? 0.363 ? ? ? ? ? ? ? ? ? 
2.08 2.28  ? ? ? ? ? ? 19143 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 0.301 ? ? 4 1 0.89  ? ? ? ? 0.222 ? ? ? ? ? ? ? ? ? 
2.28 2.55  ? ? ? ? ? ? 17119 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 0.215 ? ? 5 1 0.939 ? ? ? ? 0.162 ? ? ? ? ? ? ? ? ? 
2.55 2.94  ? ? ? ? ? ? 14360 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 0.168 ? ? 6 1 0.961 ? ? ? ? 0.129 ? ? ? ? ? ? ? ? ? 
2.94 3.6   ? ? ? ? ? ? 11327 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 0.104 ? ? 7 1 0.984 ? ? ? ? 0.08  ? ? ? ? ? ? ? ? ? 
3.60 5.08  ? ? ? ? ? ? 8360  ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 0.071 ? ? 8 1 0.991 ? ? ? ? 0.055 ? ? ? ? ? ? ? ? ? 
5.08 49.74 ? ? ? ? ? ? 4369  ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 0.069 ? ? 9 1 0.993 ? ? ? ? 0.056 ? ? ? ? ? ? ? ? ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               ? 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8W1K 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            1.70 
_refine.ls_d_res_low                             48.95 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     179979 
_refine.ls_number_reflns_R_free                  9002 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.98 
_refine.ls_percent_reflns_R_free                 5.00 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.1697 
_refine.ls_R_factor_R_free                       0.1965 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1683 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.33 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ML 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.10 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.90 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 21.07 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.29 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       1.70 
_refine_hist.d_res_low                        48.95 
_refine_hist.number_atoms_solvent             1016 
_refine_hist.number_atoms_total               10992 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        9708 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         268 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.012  ? 10218 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 1.102  ? 13876 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 14.423 ? 3762  ? f_dihedral_angle_d ? ? 
'X-RAY DIFFRACTION' ? 0.067  ? 1488  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.011  ? 1840  ? f_plane_restr      ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 1.70 1.72  . . 299 5667 100.00 . . . . 0.4694 . . . . . . . . . . . 0.4833 
'X-RAY DIFFRACTION' 1.72 1.74  . . 299 5688 100.00 . . . . 0.4004 . . . . . . . . . . . 0.4338 
'X-RAY DIFFRACTION' 1.74 1.76  . . 296 5613 100.00 . . . . 0.3647 . . . . . . . . . . . 0.3887 
'X-RAY DIFFRACTION' 1.76 1.78  . . 296 5640 100.00 . . . . 0.3484 . . . . . . . . . . . 0.3609 
'X-RAY DIFFRACTION' 1.78 1.81  . . 298 5644 100.00 . . . . 0.3292 . . . . . . . . . . . 0.3433 
'X-RAY DIFFRACTION' 1.81 1.83  . . 298 5677 100.00 . . . . 0.2977 . . . . . . . . . . . 0.3216 
'X-RAY DIFFRACTION' 1.83 1.86  . . 298 5653 100.00 . . . . 0.2494 . . . . . . . . . . . 0.2904 
'X-RAY DIFFRACTION' 1.86 1.88  . . 299 5673 100.00 . . . . 0.2364 . . . . . . . . . . . 0.2730 
'X-RAY DIFFRACTION' 1.88 1.91  . . 300 5699 100.00 . . . . 0.2319 . . . . . . . . . . . 0.2794 
'X-RAY DIFFRACTION' 1.91 1.95  . . 295 5613 100.00 . . . . 0.2296 . . . . . . . . . . . 0.2737 
'X-RAY DIFFRACTION' 1.95 1.98  . . 300 5704 100.00 . . . . 0.2296 . . . . . . . . . . . 0.2439 
'X-RAY DIFFRACTION' 1.98 2.02  . . 298 5649 100.00 . . . . 0.2468 . . . . . . . . . . . 0.2695 
'X-RAY DIFFRACTION' 2.02 2.05  . . 298 5695 100.00 . . . . 0.2220 . . . . . . . . . . . 0.2533 
'X-RAY DIFFRACTION' 2.05 2.10  . . 297 5642 100.00 . . . . 0.1868 . . . . . . . . . . . 0.2101 
'X-RAY DIFFRACTION' 2.10 2.14  . . 300 5689 100.00 . . . . 0.1773 . . . . . . . . . . . 0.2363 
'X-RAY DIFFRACTION' 2.14 2.19  . . 298 5673 100.00 . . . . 0.1694 . . . . . . . . . . . 0.2134 
'X-RAY DIFFRACTION' 2.19 2.25  . . 302 5729 100.00 . . . . 0.1646 . . . . . . . . . . . 0.2022 
'X-RAY DIFFRACTION' 2.25 2.31  . . 298 5672 100.00 . . . . 0.1551 . . . . . . . . . . . 0.1882 
'X-RAY DIFFRACTION' 2.31 2.37  . . 299 5675 100.00 . . . . 0.1512 . . . . . . . . . . . 0.1936 
'X-RAY DIFFRACTION' 2.37 2.45  . . 298 5670 100.00 . . . . 0.1467 . . . . . . . . . . . 0.1751 
'X-RAY DIFFRACTION' 2.45 2.54  . . 301 5718 100.00 . . . . 0.1514 . . . . . . . . . . . 0.1972 
'X-RAY DIFFRACTION' 2.54 2.64  . . 301 5715 100.00 . . . . 0.1542 . . . . . . . . . . . 0.1924 
'X-RAY DIFFRACTION' 2.64 2.76  . . 301 5708 100.00 . . . . 0.1659 . . . . . . . . . . . 0.1979 
'X-RAY DIFFRACTION' 2.76 2.91  . . 301 5733 100.00 . . . . 0.1599 . . . . . . . . . . . 0.1957 
'X-RAY DIFFRACTION' 2.91 3.09  . . 301 5708 100.00 . . . . 0.1656 . . . . . . . . . . . 0.1912 
'X-RAY DIFFRACTION' 3.09 3.33  . . 302 5748 100.00 . . . . 0.1618 . . . . . . . . . . . 0.2020 
'X-RAY DIFFRACTION' 3.33 3.66  . . 303 5750 100.00 . . . . 0.1480 . . . . . . . . . . . 0.1657 
'X-RAY DIFFRACTION' 3.66 4.19  . . 304 5781 100.00 . . . . 0.1276 . . . . . . . . . . . 0.1455 
'X-RAY DIFFRACTION' 4.19 5.28  . . 306 5815 100.00 . . . . 0.1217 . . . . . . . . . . . 0.1540 
'X-RAY DIFFRACTION' 5.28 48.95 . . 316 5985 100.00 . . . . 0.1468 . . . . . . . . . . . 0.1506 
# 
_struct.entry_id                     8W1K 
_struct.title                        
'Crystal Structure of a fatty acid decarboxylase from Corynebacterium lipophiloflavum in complex with oleic acid' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8W1K 
_struct_keywords.text            'P450, OXIDOREDUCTASE' 
_struct_keywords.pdbx_keywords   OXIDOREDUCTASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 1 ? 
D N N 2 ? 
E N N 3 ? 
F N N 4 ? 
G N N 5 ? 
H N N 5 ? 
I N N 5 ? 
J N N 6 ? 
K N N 7 ? 
L N N 2 ? 
M N N 3 ? 
N N N 4 ? 
O N N 5 ? 
P N N 5 ? 
Q N N 7 ? 
R N N 2 ? 
S N N 3 ? 
T N N 4 ? 
U N N 5 ? 
V N N 6 ? 
W N N 8 ? 
X N N 8 ? 
Y N N 8 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    C0XPZ5_CORLD 
_struct_ref.pdbx_db_accession          C0XPZ5 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MRMTSNQNPRVSGDRTIQFLTDGYLLPSNLRKTAGLEPESMCPVTTKLLGQDATIVRGSAGIDLFYDEDVMQREGAMPPV
IGDALVGKGAVHNLDGEEHKVRKAQMAAMAYEDERVAEFAPLVAEEVERAVAGWEGAQGNVFEDLSLAFGRAAFRWAGID
LPAENTDELVGRMITLLDNFGTATGTPKAFWQRRQLDNWAEALITDVREGRITARPDCVLEHMAQLTDASGERVDARTAG
IELQNLTRPTVAVGFFASFAAVALAENPQWRTRINESETGREAFAFAQEVRRFYPFVPMFPAKATKDTEFEGCPIHQGQR
VILDFVGTLHSAEEWDNPASFDPERFMAYETQSEAETIKPFIPQGGADVRTGHRCPGEKIAVTALSAAVEALARPEVRIS
AEAIDINYSMTEILARPKSGVRVTVASSS
;
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8W1K A 22 ? 450 ? C0XPZ5 1 ? 429 ? 1 429 
2 1 8W1K B 22 ? 450 ? C0XPZ5 1 ? 429 ? 1 429 
3 1 8W1K C 22 ? 450 ? C0XPZ5 1 ? 429 ? 1 429 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8W1K MET A 1  ? UNP C0XPZ5 ? ? 'expression tag' -20 1  
1 8W1K GLY A 2  ? UNP C0XPZ5 ? ? 'expression tag' -19 2  
1 8W1K SER A 3  ? UNP C0XPZ5 ? ? 'expression tag' -18 3  
1 8W1K SER A 4  ? UNP C0XPZ5 ? ? 'expression tag' -17 4  
1 8W1K HIS A 5  ? UNP C0XPZ5 ? ? 'expression tag' -16 5  
1 8W1K HIS A 6  ? UNP C0XPZ5 ? ? 'expression tag' -15 6  
1 8W1K HIS A 7  ? UNP C0XPZ5 ? ? 'expression tag' -14 7  
1 8W1K HIS A 8  ? UNP C0XPZ5 ? ? 'expression tag' -13 8  
1 8W1K HIS A 9  ? UNP C0XPZ5 ? ? 'expression tag' -12 9  
1 8W1K HIS A 10 ? UNP C0XPZ5 ? ? 'expression tag' -11 10 
1 8W1K SER A 11 ? UNP C0XPZ5 ? ? 'expression tag' -10 11 
1 8W1K SER A 12 ? UNP C0XPZ5 ? ? 'expression tag' -9  12 
1 8W1K GLY A 13 ? UNP C0XPZ5 ? ? 'expression tag' -8  13 
1 8W1K LEU A 14 ? UNP C0XPZ5 ? ? 'expression tag' -7  14 
1 8W1K VAL A 15 ? UNP C0XPZ5 ? ? 'expression tag' -6  15 
1 8W1K PRO A 16 ? UNP C0XPZ5 ? ? 'expression tag' -5  16 
1 8W1K ARG A 17 ? UNP C0XPZ5 ? ? 'expression tag' -4  17 
1 8W1K GLY A 18 ? UNP C0XPZ5 ? ? 'expression tag' -3  18 
1 8W1K SER A 19 ? UNP C0XPZ5 ? ? 'expression tag' -2  19 
1 8W1K HIS A 20 ? UNP C0XPZ5 ? ? 'expression tag' -1  20 
1 8W1K MET A 21 ? UNP C0XPZ5 ? ? 'expression tag' 0   21 
2 8W1K MET B 1  ? UNP C0XPZ5 ? ? 'expression tag' -20 22 
2 8W1K GLY B 2  ? UNP C0XPZ5 ? ? 'expression tag' -19 23 
2 8W1K SER B 3  ? UNP C0XPZ5 ? ? 'expression tag' -18 24 
2 8W1K SER B 4  ? UNP C0XPZ5 ? ? 'expression tag' -17 25 
2 8W1K HIS B 5  ? UNP C0XPZ5 ? ? 'expression tag' -16 26 
2 8W1K HIS B 6  ? UNP C0XPZ5 ? ? 'expression tag' -15 27 
2 8W1K HIS B 7  ? UNP C0XPZ5 ? ? 'expression tag' -14 28 
2 8W1K HIS B 8  ? UNP C0XPZ5 ? ? 'expression tag' -13 29 
2 8W1K HIS B 9  ? UNP C0XPZ5 ? ? 'expression tag' -12 30 
2 8W1K HIS B 10 ? UNP C0XPZ5 ? ? 'expression tag' -11 31 
2 8W1K SER B 11 ? UNP C0XPZ5 ? ? 'expression tag' -10 32 
2 8W1K SER B 12 ? UNP C0XPZ5 ? ? 'expression tag' -9  33 
2 8W1K GLY B 13 ? UNP C0XPZ5 ? ? 'expression tag' -8  34 
2 8W1K LEU B 14 ? UNP C0XPZ5 ? ? 'expression tag' -7  35 
2 8W1K VAL B 15 ? UNP C0XPZ5 ? ? 'expression tag' -6  36 
2 8W1K PRO B 16 ? UNP C0XPZ5 ? ? 'expression tag' -5  37 
2 8W1K ARG B 17 ? UNP C0XPZ5 ? ? 'expression tag' -4  38 
2 8W1K GLY B 18 ? UNP C0XPZ5 ? ? 'expression tag' -3  39 
2 8W1K SER B 19 ? UNP C0XPZ5 ? ? 'expression tag' -2  40 
2 8W1K HIS B 20 ? UNP C0XPZ5 ? ? 'expression tag' -1  41 
2 8W1K MET B 21 ? UNP C0XPZ5 ? ? 'expression tag' 0   42 
3 8W1K MET C 1  ? UNP C0XPZ5 ? ? 'expression tag' -20 43 
3 8W1K GLY C 2  ? UNP C0XPZ5 ? ? 'expression tag' -19 44 
3 8W1K SER C 3  ? UNP C0XPZ5 ? ? 'expression tag' -18 45 
3 8W1K SER C 4  ? UNP C0XPZ5 ? ? 'expression tag' -17 46 
3 8W1K HIS C 5  ? UNP C0XPZ5 ? ? 'expression tag' -16 47 
3 8W1K HIS C 6  ? UNP C0XPZ5 ? ? 'expression tag' -15 48 
3 8W1K HIS C 7  ? UNP C0XPZ5 ? ? 'expression tag' -14 49 
3 8W1K HIS C 8  ? UNP C0XPZ5 ? ? 'expression tag' -13 50 
3 8W1K HIS C 9  ? UNP C0XPZ5 ? ? 'expression tag' -12 51 
3 8W1K HIS C 10 ? UNP C0XPZ5 ? ? 'expression tag' -11 52 
3 8W1K SER C 11 ? UNP C0XPZ5 ? ? 'expression tag' -10 53 
3 8W1K SER C 12 ? UNP C0XPZ5 ? ? 'expression tag' -9  54 
3 8W1K GLY C 13 ? UNP C0XPZ5 ? ? 'expression tag' -8  55 
3 8W1K LEU C 14 ? UNP C0XPZ5 ? ? 'expression tag' -7  56 
3 8W1K VAL C 15 ? UNP C0XPZ5 ? ? 'expression tag' -6  57 
3 8W1K PRO C 16 ? UNP C0XPZ5 ? ? 'expression tag' -5  58 
3 8W1K ARG C 17 ? UNP C0XPZ5 ? ? 'expression tag' -4  59 
3 8W1K GLY C 18 ? UNP C0XPZ5 ? ? 'expression tag' -3  60 
3 8W1K SER C 19 ? UNP C0XPZ5 ? ? 'expression tag' -2  61 
3 8W1K HIS C 20 ? UNP C0XPZ5 ? ? 'expression tag' -1  62 
3 8W1K MET C 21 ? UNP C0XPZ5 ? ? 'expression tag' 0   63 
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 author_defined_assembly ? monomeric 1 
2 author_defined_assembly ? monomeric 1 
3 author_defined_assembly ? monomeric 1 
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 1 A,D,E,F,G,H,I,J,K,W 
2 1 B,L,M,N,O,P,Q,X     
3 1 C,R,S,T,U,V,Y       
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 ARG A 36  ? GLY A 44  ? ARG A 15  GLY A 23  1 ? 9  
HELX_P HELX_P2  AA2 LEU A 46  ? ALA A 55  ? LEU A 25  ALA A 34  1 ? 10 
HELX_P HELX_P3  AA3 ARG A 78  ? TYR A 87  ? ARG A 57  TYR A 66  1 ? 10 
HELX_P HELX_P4  AA4 PRO A 99  ? VAL A 107 ? PRO A 78  VAL A 86  1 ? 9  
HELX_P HELX_P5  AA5 ALA A 111 ? LEU A 115 ? ALA A 90  LEU A 94  5 ? 5  
HELX_P HELX_P6  AA6 ASP A 116 ? TYR A 132 ? ASP A 95  TYR A 111 1 ? 17 
HELX_P HELX_P7  AA7 GLU A 133 ? GLY A 154 ? GLU A 112 GLY A 133 1 ? 22 
HELX_P HELX_P8  AA8 VAL A 162 ? GLY A 179 ? VAL A 141 GLY A 158 1 ? 18 
HELX_P HELX_P9  AA9 PRO A 183 ? PHE A 201 ? PRO A 162 PHE A 180 1 ? 19 
HELX_P HELX_P10 AB1 GLY A 206 ? GLU A 230 ? GLY A 185 GLU A 209 1 ? 25 
HELX_P HELX_P11 AB2 CYS A 239 ? GLN A 246 ? CYS A 218 GLN A 225 1 ? 8  
HELX_P HELX_P12 AB3 ASP A 256 ? ASN A 266 ? ASP A 235 ASN A 245 1 ? 11 
HELX_P HELX_P13 AB4 THR A 268 ? ASN A 288 ? THR A 247 ASN A 267 1 ? 21 
HELX_P HELX_P14 AB5 ASN A 288 ? SER A 298 ? ASN A 267 SER A 277 1 ? 11 
HELX_P HELX_P15 AB6 GLY A 301 ? TYR A 315 ? GLY A 280 TYR A 294 1 ? 15 
HELX_P HELX_P16 AB7 PHE A 346 ? HIS A 351 ? PHE A 325 HIS A 330 1 ? 6  
HELX_P HELX_P17 AB8 ASP A 363 ? MET A 368 ? ASP A 342 MET A 347 5 ? 6  
HELX_P HELX_P18 AB9 THR A 372 ? GLU A 377 ? THR A 351 GLU A 356 1 ? 6  
HELX_P HELX_P19 AC1 GLY A 398 ? ARG A 415 ? GLY A 377 ARG A 394 1 ? 18 
HELX_P HELX_P20 AC2 GLU A 423 ? ASN A 428 ? GLU A 402 ASN A 407 1 ? 6  
HELX_P HELX_P21 AC3 ARG B 36  ? GLY B 44  ? ARG B 15  GLY B 23  1 ? 9  
HELX_P HELX_P22 AC4 LEU B 46  ? ALA B 55  ? LEU B 25  ALA B 34  1 ? 10 
HELX_P HELX_P23 AC5 ARG B 78  ? TYR B 87  ? ARG B 57  TYR B 66  1 ? 10 
HELX_P HELX_P24 AC6 PRO B 99  ? VAL B 107 ? PRO B 78  VAL B 86  1 ? 9  
HELX_P HELX_P25 AC7 ALA B 111 ? LEU B 115 ? ALA B 90  LEU B 94  5 ? 5  
HELX_P HELX_P26 AC8 ASP B 116 ? TYR B 132 ? ASP B 95  TYR B 111 1 ? 17 
HELX_P HELX_P27 AC9 GLU B 133 ? GLY B 154 ? GLU B 112 GLY B 133 1 ? 22 
HELX_P HELX_P28 AD1 VAL B 162 ? GLY B 179 ? VAL B 141 GLY B 158 1 ? 18 
HELX_P HELX_P29 AD2 PRO B 183 ? ASP B 199 ? PRO B 162 ASP B 178 1 ? 17 
HELX_P HELX_P30 AD3 GLY B 206 ? GLU B 230 ? GLY B 185 GLU B 209 1 ? 25 
HELX_P HELX_P31 AD4 CYS B 239 ? GLN B 246 ? CYS B 218 GLN B 225 1 ? 8  
HELX_P HELX_P32 AD5 ASP B 256 ? ASN B 266 ? ASP B 235 ASN B 245 1 ? 11 
HELX_P HELX_P33 AD6 THR B 268 ? ALA B 273 ? THR B 247 ALA B 252 1 ? 6  
HELX_P HELX_P34 AD7 ALA B 273 ? ASN B 288 ? ALA B 252 ASN B 267 1 ? 16 
HELX_P HELX_P35 AD8 ASN B 288 ? SER B 298 ? ASN B 267 SER B 277 1 ? 11 
HELX_P HELX_P36 AD9 GLY B 301 ? TYR B 315 ? GLY B 280 TYR B 294 1 ? 15 
HELX_P HELX_P37 AE1 PHE B 346 ? HIS B 351 ? PHE B 325 HIS B 330 1 ? 6  
HELX_P HELX_P38 AE2 ASP B 363 ? MET B 368 ? ASP B 342 MET B 347 5 ? 6  
HELX_P HELX_P39 AE3 THR B 372 ? GLU B 377 ? THR B 351 GLU B 356 1 ? 6  
HELX_P HELX_P40 AE4 GLY B 398 ? ARG B 415 ? GLY B 377 ARG B 394 1 ? 18 
HELX_P HELX_P41 AE5 GLU B 423 ? ASN B 428 ? GLU B 402 ASN B 407 1 ? 6  
HELX_P HELX_P42 AE6 THR C 37  ? GLY C 44  ? THR C 16  GLY C 23  1 ? 8  
HELX_P HELX_P43 AE7 LEU C 46  ? ALA C 55  ? LEU C 25  ALA C 34  1 ? 10 
HELX_P HELX_P44 AE8 ARG C 78  ? TYR C 87  ? ARG C 57  TYR C 66  1 ? 10 
HELX_P HELX_P45 AE9 PRO C 99  ? VAL C 107 ? PRO C 78  VAL C 86  1 ? 9  
HELX_P HELX_P46 AF1 ALA C 111 ? LEU C 115 ? ALA C 90  LEU C 94  5 ? 5  
HELX_P HELX_P47 AF2 ASP C 116 ? TYR C 132 ? ASP C 95  TYR C 111 1 ? 17 
HELX_P HELX_P48 AF3 GLU C 133 ? GLY C 154 ? GLU C 112 GLY C 133 1 ? 22 
HELX_P HELX_P49 AF4 VAL C 162 ? GLY C 179 ? VAL C 141 GLY C 158 1 ? 18 
HELX_P HELX_P50 AF5 PRO C 183 ? PHE C 201 ? PRO C 162 PHE C 180 1 ? 19 
HELX_P HELX_P51 AF6 GLY C 206 ? GLU C 230 ? GLY C 185 GLU C 209 1 ? 25 
HELX_P HELX_P52 AF7 CYS C 239 ? GLN C 246 ? CYS C 218 GLN C 225 1 ? 8  
HELX_P HELX_P53 AF8 ASP C 256 ? ASN C 266 ? ASP C 235 ASN C 245 1 ? 11 
HELX_P HELX_P54 AF9 THR C 268 ? ASN C 288 ? THR C 247 ASN C 267 1 ? 21 
HELX_P HELX_P55 AG1 ASN C 288 ? SER C 298 ? ASN C 267 SER C 277 1 ? 11 
HELX_P HELX_P56 AG2 GLY C 301 ? TYR C 315 ? GLY C 280 TYR C 294 1 ? 15 
HELX_P HELX_P57 AG3 PHE C 346 ? HIS C 351 ? PHE C 325 HIS C 330 1 ? 6  
HELX_P HELX_P58 AG4 ASP C 363 ? MET C 368 ? ASP C 342 MET C 347 5 ? 6  
HELX_P HELX_P59 AG5 THR C 372 ? GLU C 377 ? THR C 351 GLU C 356 1 ? 6  
HELX_P HELX_P60 AG6 GLY C 398 ? ARG C 415 ? GLY C 377 ARG C 394 1 ? 18 
HELX_P HELX_P61 AG7 GLU C 423 ? ASN C 428 ? GLU C 402 ASN C 407 1 ? 6  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
metalc1 metalc ? ? A CYS 396 SG ? ? ? 1_555 D HEM . FE ? ? A CYS 375 A HEM 501 1_555 ? ? ? ? ? ? ? 2.373 ? ? 
metalc2 metalc ? ? B CYS 396 SG ? ? ? 1_555 L HEM . FE ? ? B CYS 375 B HEM 501 1_555 ? ? ? ? ? ? ? 2.344 ? ? 
metalc3 metalc ? ? C CYS 396 SG ? ? ? 1_555 R HEM . FE ? ? C CYS 375 C HEM 501 1_555 ? ? ? ? ? ? ? 2.358 ? ? 
# 
_struct_conn_type.id          metalc 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1  SG ? A CYS 396 ? A CYS 375 ? 1_555 FE ? D HEM . ? A HEM 501 ? 1_555 NA ? D HEM . ? A HEM 501 ? 1_555 103.9 ? 
2  SG ? A CYS 396 ? A CYS 375 ? 1_555 FE ? D HEM . ? A HEM 501 ? 1_555 NB ? D HEM . ? A HEM 501 ? 1_555 95.9  ? 
3  NA ? D HEM .   ? A HEM 501 ? 1_555 FE ? D HEM . ? A HEM 501 ? 1_555 NB ? D HEM . ? A HEM 501 ? 1_555 89.9  ? 
4  SG ? A CYS 396 ? A CYS 375 ? 1_555 FE ? D HEM . ? A HEM 501 ? 1_555 NC ? D HEM . ? A HEM 501 ? 1_555 90.0  ? 
5  NA ? D HEM .   ? A HEM 501 ? 1_555 FE ? D HEM . ? A HEM 501 ? 1_555 NC ? D HEM . ? A HEM 501 ? 1_555 166.1 ? 
6  NB ? D HEM .   ? A HEM 501 ? 1_555 FE ? D HEM . ? A HEM 501 ? 1_555 NC ? D HEM . ? A HEM 501 ? 1_555 87.7  ? 
7  SG ? A CYS 396 ? A CYS 375 ? 1_555 FE ? D HEM . ? A HEM 501 ? 1_555 ND ? D HEM . ? A HEM 501 ? 1_555 98.8  ? 
8  NA ? D HEM .   ? A HEM 501 ? 1_555 FE ? D HEM . ? A HEM 501 ? 1_555 ND ? D HEM . ? A HEM 501 ? 1_555 88.5  ? 
9  NB ? D HEM .   ? A HEM 501 ? 1_555 FE ? D HEM . ? A HEM 501 ? 1_555 ND ? D HEM . ? A HEM 501 ? 1_555 165.2 ? 
10 NC ? D HEM .   ? A HEM 501 ? 1_555 FE ? D HEM . ? A HEM 501 ? 1_555 ND ? D HEM . ? A HEM 501 ? 1_555 90.3  ? 
11 SG ? B CYS 396 ? B CYS 375 ? 1_555 FE ? L HEM . ? B HEM 501 ? 1_555 NA ? L HEM . ? B HEM 501 ? 1_555 103.1 ? 
12 SG ? B CYS 396 ? B CYS 375 ? 1_555 FE ? L HEM . ? B HEM 501 ? 1_555 NB ? L HEM . ? B HEM 501 ? 1_555 96.0  ? 
13 NA ? L HEM .   ? B HEM 501 ? 1_555 FE ? L HEM . ? B HEM 501 ? 1_555 NB ? L HEM . ? B HEM 501 ? 1_555 88.6  ? 
14 SG ? B CYS 396 ? B CYS 375 ? 1_555 FE ? L HEM . ? B HEM 501 ? 1_555 NC ? L HEM . ? B HEM 501 ? 1_555 90.6  ? 
15 NA ? L HEM .   ? B HEM 501 ? 1_555 FE ? L HEM . ? B HEM 501 ? 1_555 NC ? L HEM . ? B HEM 501 ? 1_555 166.3 ? 
16 NB ? L HEM .   ? B HEM 501 ? 1_555 FE ? L HEM . ? B HEM 501 ? 1_555 NC ? L HEM . ? B HEM 501 ? 1_555 90.5  ? 
17 SG ? B CYS 396 ? B CYS 375 ? 1_555 FE ? L HEM . ? B HEM 501 ? 1_555 ND ? L HEM . ? B HEM 501 ? 1_555 98.9  ? 
18 NA ? L HEM .   ? B HEM 501 ? 1_555 FE ? L HEM . ? B HEM 501 ? 1_555 ND ? L HEM . ? B HEM 501 ? 1_555 88.7  ? 
19 NB ? L HEM .   ? B HEM 501 ? 1_555 FE ? L HEM . ? B HEM 501 ? 1_555 ND ? L HEM . ? B HEM 501 ? 1_555 165.0 ? 
20 NC ? L HEM .   ? B HEM 501 ? 1_555 FE ? L HEM . ? B HEM 501 ? 1_555 ND ? L HEM . ? B HEM 501 ? 1_555 88.7  ? 
21 SG ? C CYS 396 ? C CYS 375 ? 1_555 FE ? R HEM . ? C HEM 501 ? 1_555 NA ? R HEM . ? C HEM 501 ? 1_555 103.9 ? 
22 SG ? C CYS 396 ? C CYS 375 ? 1_555 FE ? R HEM . ? C HEM 501 ? 1_555 NB ? R HEM . ? C HEM 501 ? 1_555 93.6  ? 
23 NA ? R HEM .   ? C HEM 501 ? 1_555 FE ? R HEM . ? C HEM 501 ? 1_555 NB ? R HEM . ? C HEM 501 ? 1_555 88.6  ? 
24 SG ? C CYS 396 ? C CYS 375 ? 1_555 FE ? R HEM . ? C HEM 501 ? 1_555 NC ? R HEM . ? C HEM 501 ? 1_555 90.2  ? 
25 NA ? R HEM .   ? C HEM 501 ? 1_555 FE ? R HEM . ? C HEM 501 ? 1_555 NC ? R HEM . ? C HEM 501 ? 1_555 165.8 ? 
26 NB ? R HEM .   ? C HEM 501 ? 1_555 FE ? R HEM . ? C HEM 501 ? 1_555 NC ? R HEM . ? C HEM 501 ? 1_555 88.9  ? 
27 SG ? C CYS 396 ? C CYS 375 ? 1_555 FE ? R HEM . ? C HEM 501 ? 1_555 ND ? R HEM . ? C HEM 501 ? 1_555 99.9  ? 
28 NA ? R HEM .   ? C HEM 501 ? 1_555 FE ? R HEM . ? C HEM 501 ? 1_555 ND ? R HEM . ? C HEM 501 ? 1_555 86.7  ? 
29 NB ? R HEM .   ? C HEM 501 ? 1_555 FE ? R HEM . ? C HEM 501 ? 1_555 ND ? R HEM . ? C HEM 501 ? 1_555 166.4 ? 
30 NC ? R HEM .   ? C HEM 501 ? 1_555 FE ? R HEM . ? C HEM 501 ? 1_555 ND ? R HEM . ? C HEM 501 ? 1_555 92.6  ? 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 ILE 434 A . ? ILE 413 A LEU 435 A ? LEU 414 A 1 -7.94  
2 ILE 434 B . ? ILE 413 B LEU 435 B ? LEU 414 B 1 -9.25  
3 ILE 434 C . ? ILE 413 C LEU 435 C ? LEU 414 C 1 -10.82 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 6 ? 
AA2 ? 3 ? 
AA3 ? 2 ? 
AA4 ? 6 ? 
AA5 ? 3 ? 
AA6 ? 2 ? 
AA7 ? 6 ? 
AA8 ? 3 ? 
AA9 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? parallel      
AA1 2 3 ? anti-parallel 
AA1 3 4 ? parallel      
AA1 4 5 ? anti-parallel 
AA1 5 6 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA4 1 2 ? parallel      
AA4 2 3 ? anti-parallel 
AA4 3 4 ? parallel      
AA4 4 5 ? anti-parallel 
AA4 5 6 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA7 1 2 ? parallel      
AA7 2 3 ? anti-parallel 
AA7 3 4 ? parallel      
AA7 4 5 ? anti-parallel 
AA7 5 6 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA9 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ARG A 31  ? ASP A 35  ? ARG A 10  ASP A 14  
AA1 2 VAL A 65  ? LEU A 69  ? VAL A 44  LEU A 48  
AA1 3 GLN A 72  ? VAL A 77  ? GLN A 51  VAL A 56  
AA1 4 ARG A 341 ? ASP A 345 ? ARG A 320 ASP A 324 
AA1 5 MET A 320 ? ALA A 325 ? MET A 299 ALA A 304 
AA1 6 MET A 92  ? GLN A 93  ? MET A 71  GLN A 72  
AA2 1 GLY A 160 ? ASN A 161 ? GLY A 139 ASN A 140 
AA2 2 ARG A 443 ? VAL A 446 ? ARG A 422 VAL A 425 
AA2 3 VAL A 418 ? ILE A 420 ? VAL A 397 ILE A 399 
AA3 1 THR A 329 ? PHE A 331 ? THR A 308 PHE A 310 
AA3 2 CYS A 334 ? ILE A 336 ? CYS A 313 ILE A 315 
AA4 1 ARG B 31  ? ASP B 35  ? ARG B 10  ASP B 14  
AA4 2 VAL B 65  ? LEU B 69  ? VAL B 44  LEU B 48  
AA4 3 GLN B 72  ? VAL B 77  ? GLN B 51  VAL B 56  
AA4 4 ARG B 341 ? ASP B 345 ? ARG B 320 ASP B 324 
AA4 5 MET B 320 ? ALA B 325 ? MET B 299 ALA B 304 
AA4 6 MET B 92  ? GLN B 93  ? MET B 71  GLN B 72  
AA5 1 GLY B 160 ? ASN B 161 ? GLY B 139 ASN B 140 
AA5 2 ARG B 443 ? VAL B 446 ? ARG B 422 VAL B 425 
AA5 3 VAL B 418 ? ILE B 420 ? VAL B 397 ILE B 399 
AA6 1 THR B 329 ? PHE B 331 ? THR B 308 PHE B 310 
AA6 2 CYS B 334 ? ILE B 336 ? CYS B 313 ILE B 315 
AA7 1 ARG C 31  ? ASP C 35  ? ARG C 10  ASP C 14  
AA7 2 VAL C 65  ? LEU C 69  ? VAL C 44  LEU C 48  
AA7 3 GLN C 72  ? VAL C 77  ? GLN C 51  VAL C 56  
AA7 4 ARG C 341 ? ASP C 345 ? ARG C 320 ASP C 324 
AA7 5 MET C 320 ? ALA C 325 ? MET C 299 ALA C 304 
AA7 6 MET C 92  ? GLN C 93  ? MET C 71  GLN C 72  
AA8 1 GLY C 160 ? ASN C 161 ? GLY C 139 ASN C 140 
AA8 2 ARG C 443 ? THR C 445 ? ARG C 422 THR C 424 
AA8 3 ARG C 419 ? ILE C 420 ? ARG C 398 ILE C 399 
AA9 1 THR C 329 ? PHE C 331 ? THR C 308 PHE C 310 
AA9 2 CYS C 334 ? ILE C 336 ? CYS C 313 ILE C 315 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N VAL A 32  ? N VAL A 11  O THR A 66  ? O THR A 45  
AA1 2 3 N VAL A 65  ? N VAL A 44  O ILE A 76  ? O ILE A 55  
AA1 3 4 N VAL A 77  ? N VAL A 56  O ASP A 345 ? O ASP A 324 
AA1 4 5 O LEU A 344 ? O LEU A 323 N PHE A 321 ? N PHE A 300 
AA1 5 6 O LYS A 324 ? O LYS A 303 N GLN A 93  ? N GLN A 72  
AA2 1 2 N GLY A 160 ? N GLY A 139 O VAL A 444 ? O VAL A 423 
AA2 2 3 O THR A 445 ? O THR A 424 N ARG A 419 ? N ARG A 398 
AA3 1 2 N THR A 329 ? N THR A 308 O ILE A 336 ? O ILE A 315 
AA4 1 2 N VAL B 32  ? N VAL B 11  O THR B 66  ? O THR B 45  
AA4 2 3 N VAL B 65  ? N VAL B 44  O ILE B 76  ? O ILE B 55  
AA4 3 4 N VAL B 77  ? N VAL B 56  O ASP B 345 ? O ASP B 324 
AA4 4 5 O LEU B 344 ? O LEU B 323 N PHE B 321 ? N PHE B 300 
AA4 5 6 O LYS B 324 ? O LYS B 303 N GLN B 93  ? N GLN B 72  
AA5 1 2 N GLY B 160 ? N GLY B 139 O VAL B 444 ? O VAL B 423 
AA5 2 3 O THR B 445 ? O THR B 424 N ARG B 419 ? N ARG B 398 
AA6 1 2 N THR B 329 ? N THR B 308 O ILE B 336 ? O ILE B 315 
AA7 1 2 N VAL C 32  ? N VAL C 11  O THR C 66  ? O THR C 45  
AA7 2 3 N VAL C 65  ? N VAL C 44  O ILE C 76  ? O ILE C 55  
AA7 3 4 N VAL C 77  ? N VAL C 56  O ASP C 345 ? O ASP C 324 
AA7 4 5 O LEU C 344 ? O LEU C 323 N PHE C 321 ? N PHE C 300 
AA7 5 6 O LYS C 324 ? O LYS C 303 N GLN C 93  ? N GLN C 72  
AA8 1 2 N GLY C 160 ? N GLY C 139 O VAL C 444 ? O VAL C 423 
AA8 2 3 O THR C 445 ? O THR C 424 N ARG C 419 ? N ARG C 398 
AA9 1 2 N THR C 329 ? N THR C 308 O ILE C 336 ? O ILE C 315 
# 
_pdbx_entry_details.entry_id                   8W1K 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 THR A 247 ? ? -134.63 -48.71  
2  1 PHE A 296 ? ? -138.32 -74.51  
3  1 ALA A 367 ? ? 59.60   -144.51 
4  1 VAL A 421 ? ? 79.79   102.76  
5  1 THR B 247 ? ? -130.31 -49.39  
6  1 PHE B 296 ? ? -135.70 -75.05  
7  1 ALA B 367 ? ? 56.16   -141.17 
8  1 VAL B 421 ? ? 76.65   100.04  
9  1 THR C 247 ? ? -136.01 -50.30  
10 1 PHE C 296 ? ? -140.79 -72.90  
11 1 ALA C 367 ? ? 61.65   -145.52 
12 1 VAL C 421 ? ? 77.58   102.72  
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A MET -20 ? A MET 1   
2  1 Y 1 A GLY -19 ? A GLY 2   
3  1 Y 1 A SER -18 ? A SER 3   
4  1 Y 1 A SER -17 ? A SER 4   
5  1 Y 1 A HIS -16 ? A HIS 5   
6  1 Y 1 A HIS -15 ? A HIS 6   
7  1 Y 1 A HIS -14 ? A HIS 7   
8  1 Y 1 A HIS -13 ? A HIS 8   
9  1 Y 1 A HIS -12 ? A HIS 9   
10 1 Y 1 A HIS -11 ? A HIS 10  
11 1 Y 1 A SER -10 ? A SER 11  
12 1 Y 1 A SER -9  ? A SER 12  
13 1 Y 1 A GLY -8  ? A GLY 13  
14 1 Y 1 A LEU -7  ? A LEU 14  
15 1 Y 1 A VAL -6  ? A VAL 15  
16 1 Y 1 A PRO -5  ? A PRO 16  
17 1 Y 1 A ARG -4  ? A ARG 17  
18 1 Y 1 A GLY -3  ? A GLY 18  
19 1 Y 1 A SER -2  ? A SER 19  
20 1 Y 1 A HIS -1  ? A HIS 20  
21 1 Y 1 A MET 0   ? A MET 21  
22 1 Y 1 A MET 1   ? A MET 22  
23 1 Y 1 A ARG 2   ? A ARG 23  
24 1 Y 1 A MET 3   ? A MET 24  
25 1 Y 1 A THR 4   ? A THR 25  
26 1 Y 1 A SER 5   ? A SER 26  
27 1 Y 1 A ASN 6   ? A ASN 27  
28 1 Y 1 A GLN 7   ? A GLN 28  
29 1 Y 1 A ASN 8   ? A ASN 29  
30 1 Y 1 A SER 429 ? A SER 450 
31 1 Y 1 B MET -20 ? B MET 1   
32 1 Y 1 B GLY -19 ? B GLY 2   
33 1 Y 1 B SER -18 ? B SER 3   
34 1 Y 1 B SER -17 ? B SER 4   
35 1 Y 1 B HIS -16 ? B HIS 5   
36 1 Y 1 B HIS -15 ? B HIS 6   
37 1 Y 1 B HIS -14 ? B HIS 7   
38 1 Y 1 B HIS -13 ? B HIS 8   
39 1 Y 1 B HIS -12 ? B HIS 9   
40 1 Y 1 B HIS -11 ? B HIS 10  
41 1 Y 1 B SER -10 ? B SER 11  
42 1 Y 1 B SER -9  ? B SER 12  
43 1 Y 1 B GLY -8  ? B GLY 13  
44 1 Y 1 B LEU -7  ? B LEU 14  
45 1 Y 1 B VAL -6  ? B VAL 15  
46 1 Y 1 B PRO -5  ? B PRO 16  
47 1 Y 1 B ARG -4  ? B ARG 17  
48 1 Y 1 B GLY -3  ? B GLY 18  
49 1 Y 1 B SER -2  ? B SER 19  
50 1 Y 1 B HIS -1  ? B HIS 20  
51 1 Y 1 B MET 0   ? B MET 21  
52 1 Y 1 B MET 1   ? B MET 22  
53 1 Y 1 B ARG 2   ? B ARG 23  
54 1 Y 1 B MET 3   ? B MET 24  
55 1 Y 1 B THR 4   ? B THR 25  
56 1 Y 1 B SER 5   ? B SER 26  
57 1 Y 1 B ASN 6   ? B ASN 27  
58 1 Y 1 B GLN 7   ? B GLN 28  
59 1 Y 1 B SER 429 ? B SER 450 
60 1 Y 1 C MET -20 ? C MET 1   
61 1 Y 1 C GLY -19 ? C GLY 2   
62 1 Y 1 C SER -18 ? C SER 3   
63 1 Y 1 C SER -17 ? C SER 4   
64 1 Y 1 C HIS -16 ? C HIS 5   
65 1 Y 1 C HIS -15 ? C HIS 6   
66 1 Y 1 C HIS -14 ? C HIS 7   
67 1 Y 1 C HIS -13 ? C HIS 8   
68 1 Y 1 C HIS -12 ? C HIS 9   
69 1 Y 1 C HIS -11 ? C HIS 10  
70 1 Y 1 C SER -10 ? C SER 11  
71 1 Y 1 C SER -9  ? C SER 12  
72 1 Y 1 C GLY -8  ? C GLY 13  
73 1 Y 1 C LEU -7  ? C LEU 14  
74 1 Y 1 C VAL -6  ? C VAL 15  
75 1 Y 1 C PRO -5  ? C PRO 16  
76 1 Y 1 C ARG -4  ? C ARG 17  
77 1 Y 1 C GLY -3  ? C GLY 18  
78 1 Y 1 C SER -2  ? C SER 19  
79 1 Y 1 C HIS -1  ? C HIS 20  
80 1 Y 1 C MET 0   ? C MET 21  
81 1 Y 1 C MET 1   ? C MET 22  
82 1 Y 1 C ARG 2   ? C ARG 23  
83 1 Y 1 C MET 3   ? C MET 24  
84 1 Y 1 C THR 4   ? C THR 25  
85 1 Y 1 C SER 5   ? C SER 26  
86 1 Y 1 C ASN 6   ? C ASN 27  
87 1 Y 1 C GLN 7   ? C GLN 28  
88 1 Y 1 C ALA 426 ? C ALA 447 
89 1 Y 1 C SER 427 ? C SER 448 
90 1 Y 1 C SER 428 ? C SER 449 
91 1 Y 1 C SER 429 ? C SER 450 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N  N N 1   
ALA CA   C  N S 2   
ALA C    C  N N 3   
ALA O    O  N N 4   
ALA CB   C  N N 5   
ALA OXT  O  N N 6   
ALA H    H  N N 7   
ALA H2   H  N N 8   
ALA HA   H  N N 9   
ALA HB1  H  N N 10  
ALA HB2  H  N N 11  
ALA HB3  H  N N 12  
ALA HXT  H  N N 13  
ARG N    N  N N 14  
ARG CA   C  N S 15  
ARG C    C  N N 16  
ARG O    O  N N 17  
ARG CB   C  N N 18  
ARG CG   C  N N 19  
ARG CD   C  N N 20  
ARG NE   N  N N 21  
ARG CZ   C  N N 22  
ARG NH1  N  N N 23  
ARG NH2  N  N N 24  
ARG OXT  O  N N 25  
ARG H    H  N N 26  
ARG H2   H  N N 27  
ARG HA   H  N N 28  
ARG HB2  H  N N 29  
ARG HB3  H  N N 30  
ARG HG2  H  N N 31  
ARG HG3  H  N N 32  
ARG HD2  H  N N 33  
ARG HD3  H  N N 34  
ARG HE   H  N N 35  
ARG HH11 H  N N 36  
ARG HH12 H  N N 37  
ARG HH21 H  N N 38  
ARG HH22 H  N N 39  
ARG HXT  H  N N 40  
ASN N    N  N N 41  
ASN CA   C  N S 42  
ASN C    C  N N 43  
ASN O    O  N N 44  
ASN CB   C  N N 45  
ASN CG   C  N N 46  
ASN OD1  O  N N 47  
ASN ND2  N  N N 48  
ASN OXT  O  N N 49  
ASN H    H  N N 50  
ASN H2   H  N N 51  
ASN HA   H  N N 52  
ASN HB2  H  N N 53  
ASN HB3  H  N N 54  
ASN HD21 H  N N 55  
ASN HD22 H  N N 56  
ASN HXT  H  N N 57  
ASP N    N  N N 58  
ASP CA   C  N S 59  
ASP C    C  N N 60  
ASP O    O  N N 61  
ASP CB   C  N N 62  
ASP CG   C  N N 63  
ASP OD1  O  N N 64  
ASP OD2  O  N N 65  
ASP OXT  O  N N 66  
ASP H    H  N N 67  
ASP H2   H  N N 68  
ASP HA   H  N N 69  
ASP HB2  H  N N 70  
ASP HB3  H  N N 71  
ASP HD2  H  N N 72  
ASP HXT  H  N N 73  
CL  CL   CL N N 74  
CYS N    N  N N 75  
CYS CA   C  N R 76  
CYS C    C  N N 77  
CYS O    O  N N 78  
CYS CB   C  N N 79  
CYS SG   S  N N 80  
CYS OXT  O  N N 81  
CYS H    H  N N 82  
CYS H2   H  N N 83  
CYS HA   H  N N 84  
CYS HB2  H  N N 85  
CYS HB3  H  N N 86  
CYS HG   H  N N 87  
CYS HXT  H  N N 88  
GLN N    N  N N 89  
GLN CA   C  N S 90  
GLN C    C  N N 91  
GLN O    O  N N 92  
GLN CB   C  N N 93  
GLN CG   C  N N 94  
GLN CD   C  N N 95  
GLN OE1  O  N N 96  
GLN NE2  N  N N 97  
GLN OXT  O  N N 98  
GLN H    H  N N 99  
GLN H2   H  N N 100 
GLN HA   H  N N 101 
GLN HB2  H  N N 102 
GLN HB3  H  N N 103 
GLN HG2  H  N N 104 
GLN HG3  H  N N 105 
GLN HE21 H  N N 106 
GLN HE22 H  N N 107 
GLN HXT  H  N N 108 
GLU N    N  N N 109 
GLU CA   C  N S 110 
GLU C    C  N N 111 
GLU O    O  N N 112 
GLU CB   C  N N 113 
GLU CG   C  N N 114 
GLU CD   C  N N 115 
GLU OE1  O  N N 116 
GLU OE2  O  N N 117 
GLU OXT  O  N N 118 
GLU H    H  N N 119 
GLU H2   H  N N 120 
GLU HA   H  N N 121 
GLU HB2  H  N N 122 
GLU HB3  H  N N 123 
GLU HG2  H  N N 124 
GLU HG3  H  N N 125 
GLU HE2  H  N N 126 
GLU HXT  H  N N 127 
GLY N    N  N N 128 
GLY CA   C  N N 129 
GLY C    C  N N 130 
GLY O    O  N N 131 
GLY OXT  O  N N 132 
GLY H    H  N N 133 
GLY H2   H  N N 134 
GLY HA2  H  N N 135 
GLY HA3  H  N N 136 
GLY HXT  H  N N 137 
GOL C1   C  N N 138 
GOL O1   O  N N 139 
GOL C2   C  N N 140 
GOL O2   O  N N 141 
GOL C3   C  N N 142 
GOL O3   O  N N 143 
GOL H11  H  N N 144 
GOL H12  H  N N 145 
GOL HO1  H  N N 146 
GOL H2   H  N N 147 
GOL HO2  H  N N 148 
GOL H31  H  N N 149 
GOL H32  H  N N 150 
GOL HO3  H  N N 151 
HEM CHA  C  N N 152 
HEM CHB  C  N N 153 
HEM CHC  C  N N 154 
HEM CHD  C  N N 155 
HEM C1A  C  Y N 156 
HEM C2A  C  Y N 157 
HEM C3A  C  Y N 158 
HEM C4A  C  Y N 159 
HEM CMA  C  N N 160 
HEM CAA  C  N N 161 
HEM CBA  C  N N 162 
HEM CGA  C  N N 163 
HEM O1A  O  N N 164 
HEM O2A  O  N N 165 
HEM C1B  C  N N 166 
HEM C2B  C  N N 167 
HEM C3B  C  N N 168 
HEM C4B  C  N N 169 
HEM CMB  C  N N 170 
HEM CAB  C  N N 171 
HEM CBB  C  N N 172 
HEM C1C  C  Y N 173 
HEM C2C  C  Y N 174 
HEM C3C  C  Y N 175 
HEM C4C  C  Y N 176 
HEM CMC  C  N N 177 
HEM CAC  C  N N 178 
HEM CBC  C  N N 179 
HEM C1D  C  N N 180 
HEM C2D  C  N N 181 
HEM C3D  C  N N 182 
HEM C4D  C  N N 183 
HEM CMD  C  N N 184 
HEM CAD  C  N N 185 
HEM CBD  C  N N 186 
HEM CGD  C  N N 187 
HEM O1D  O  N N 188 
HEM O2D  O  N N 189 
HEM NA   N  Y N 190 
HEM NB   N  N N 191 
HEM NC   N  Y N 192 
HEM ND   N  N N 193 
HEM FE   FE N N 194 
HEM HHB  H  N N 195 
HEM HHC  H  N N 196 
HEM HHD  H  N N 197 
HEM HMA  H  N N 198 
HEM HMAA H  N N 199 
HEM HMAB H  N N 200 
HEM HAA  H  N N 201 
HEM HAAA H  N N 202 
HEM HBA  H  N N 203 
HEM HBAA H  N N 204 
HEM HMB  H  N N 205 
HEM HMBA H  N N 206 
HEM HMBB H  N N 207 
HEM HAB  H  N N 208 
HEM HBB  H  N N 209 
HEM HBBA H  N N 210 
HEM HMC  H  N N 211 
HEM HMCA H  N N 212 
HEM HMCB H  N N 213 
HEM HAC  H  N N 214 
HEM HBC  H  N N 215 
HEM HBCA H  N N 216 
HEM HMD  H  N N 217 
HEM HMDA H  N N 218 
HEM HMDB H  N N 219 
HEM HAD  H  N N 220 
HEM HADA H  N N 221 
HEM HBD  H  N N 222 
HEM HBDA H  N N 223 
HEM H2A  H  N N 224 
HEM H2D  H  N N 225 
HEM HHA  H  N N 226 
HIS N    N  N N 227 
HIS CA   C  N S 228 
HIS C    C  N N 229 
HIS O    O  N N 230 
HIS CB   C  N N 231 
HIS CG   C  Y N 232 
HIS ND1  N  Y N 233 
HIS CD2  C  Y N 234 
HIS CE1  C  Y N 235 
HIS NE2  N  Y N 236 
HIS OXT  O  N N 237 
HIS H    H  N N 238 
HIS H2   H  N N 239 
HIS HA   H  N N 240 
HIS HB2  H  N N 241 
HIS HB3  H  N N 242 
HIS HD1  H  N N 243 
HIS HD2  H  N N 244 
HIS HE1  H  N N 245 
HIS HE2  H  N N 246 
HIS HXT  H  N N 247 
HOH O    O  N N 248 
HOH H1   H  N N 249 
HOH H2   H  N N 250 
ILE N    N  N N 251 
ILE CA   C  N S 252 
ILE C    C  N N 253 
ILE O    O  N N 254 
ILE CB   C  N S 255 
ILE CG1  C  N N 256 
ILE CG2  C  N N 257 
ILE CD1  C  N N 258 
ILE OXT  O  N N 259 
ILE H    H  N N 260 
ILE H2   H  N N 261 
ILE HA   H  N N 262 
ILE HB   H  N N 263 
ILE HG12 H  N N 264 
ILE HG13 H  N N 265 
ILE HG21 H  N N 266 
ILE HG22 H  N N 267 
ILE HG23 H  N N 268 
ILE HD11 H  N N 269 
ILE HD12 H  N N 270 
ILE HD13 H  N N 271 
ILE HXT  H  N N 272 
LEU N    N  N N 273 
LEU CA   C  N S 274 
LEU C    C  N N 275 
LEU O    O  N N 276 
LEU CB   C  N N 277 
LEU CG   C  N N 278 
LEU CD1  C  N N 279 
LEU CD2  C  N N 280 
LEU OXT  O  N N 281 
LEU H    H  N N 282 
LEU H2   H  N N 283 
LEU HA   H  N N 284 
LEU HB2  H  N N 285 
LEU HB3  H  N N 286 
LEU HG   H  N N 287 
LEU HD11 H  N N 288 
LEU HD12 H  N N 289 
LEU HD13 H  N N 290 
LEU HD21 H  N N 291 
LEU HD22 H  N N 292 
LEU HD23 H  N N 293 
LEU HXT  H  N N 294 
LYS N    N  N N 295 
LYS CA   C  N S 296 
LYS C    C  N N 297 
LYS O    O  N N 298 
LYS CB   C  N N 299 
LYS CG   C  N N 300 
LYS CD   C  N N 301 
LYS CE   C  N N 302 
LYS NZ   N  N N 303 
LYS OXT  O  N N 304 
LYS H    H  N N 305 
LYS H2   H  N N 306 
LYS HA   H  N N 307 
LYS HB2  H  N N 308 
LYS HB3  H  N N 309 
LYS HG2  H  N N 310 
LYS HG3  H  N N 311 
LYS HD2  H  N N 312 
LYS HD3  H  N N 313 
LYS HE2  H  N N 314 
LYS HE3  H  N N 315 
LYS HZ1  H  N N 316 
LYS HZ2  H  N N 317 
LYS HZ3  H  N N 318 
LYS HXT  H  N N 319 
MET N    N  N N 320 
MET CA   C  N S 321 
MET C    C  N N 322 
MET O    O  N N 323 
MET CB   C  N N 324 
MET CG   C  N N 325 
MET SD   S  N N 326 
MET CE   C  N N 327 
MET OXT  O  N N 328 
MET H    H  N N 329 
MET H2   H  N N 330 
MET HA   H  N N 331 
MET HB2  H  N N 332 
MET HB3  H  N N 333 
MET HG2  H  N N 334 
MET HG3  H  N N 335 
MET HE1  H  N N 336 
MET HE2  H  N N 337 
MET HE3  H  N N 338 
MET HXT  H  N N 339 
OLA C1   C  N N 340 
OLA O1   O  N N 341 
OLA O2   O  N N 342 
OLA C2   C  N N 343 
OLA C3   C  N N 344 
OLA C4   C  N N 345 
OLA C5   C  N N 346 
OLA C6   C  N N 347 
OLA C7   C  N N 348 
OLA C8   C  N N 349 
OLA C9   C  N N 350 
OLA C10  C  N N 351 
OLA C11  C  N N 352 
OLA C12  C  N N 353 
OLA C13  C  N N 354 
OLA C14  C  N N 355 
OLA C15  C  N N 356 
OLA C16  C  N N 357 
OLA C17  C  N N 358 
OLA C18  C  N N 359 
OLA HO2  H  N N 360 
OLA H21  H  N N 361 
OLA H22  H  N N 362 
OLA H31  H  N N 363 
OLA H32  H  N N 364 
OLA H41  H  N N 365 
OLA H42  H  N N 366 
OLA H51  H  N N 367 
OLA H52  H  N N 368 
OLA H61  H  N N 369 
OLA H62  H  N N 370 
OLA H71  H  N N 371 
OLA H72  H  N N 372 
OLA H81  H  N N 373 
OLA H82  H  N N 374 
OLA H9   H  N N 375 
OLA H10  H  N N 376 
OLA H111 H  N N 377 
OLA H112 H  N N 378 
OLA H121 H  N N 379 
OLA H122 H  N N 380 
OLA H131 H  N N 381 
OLA H132 H  N N 382 
OLA H141 H  N N 383 
OLA H142 H  N N 384 
OLA H151 H  N N 385 
OLA H152 H  N N 386 
OLA H161 H  N N 387 
OLA H162 H  N N 388 
OLA H171 H  N N 389 
OLA H172 H  N N 390 
OLA H181 H  N N 391 
OLA H182 H  N N 392 
OLA H183 H  N N 393 
PEG C1   C  N N 394 
PEG O1   O  N N 395 
PEG C2   C  N N 396 
PEG O2   O  N N 397 
PEG C3   C  N N 398 
PEG C4   C  N N 399 
PEG O4   O  N N 400 
PEG H11  H  N N 401 
PEG H12  H  N N 402 
PEG HO1  H  N N 403 
PEG H21  H  N N 404 
PEG H22  H  N N 405 
PEG H31  H  N N 406 
PEG H32  H  N N 407 
PEG H41  H  N N 408 
PEG H42  H  N N 409 
PEG HO4  H  N N 410 
PGE C1   C  N N 411 
PGE O1   O  N N 412 
PGE C2   C  N N 413 
PGE O2   O  N N 414 
PGE C3   C  N N 415 
PGE C4   C  N N 416 
PGE O4   O  N N 417 
PGE C6   C  N N 418 
PGE C5   C  N N 419 
PGE O3   O  N N 420 
PGE H1   H  N N 421 
PGE H12  H  N N 422 
PGE HO1  H  N N 423 
PGE H2   H  N N 424 
PGE H22  H  N N 425 
PGE H3   H  N N 426 
PGE H32  H  N N 427 
PGE H4   H  N N 428 
PGE H42  H  N N 429 
PGE HO4  H  N N 430 
PGE H6   H  N N 431 
PGE H62  H  N N 432 
PGE H5   H  N N 433 
PGE H52  H  N N 434 
PHE N    N  N N 435 
PHE CA   C  N S 436 
PHE C    C  N N 437 
PHE O    O  N N 438 
PHE CB   C  N N 439 
PHE CG   C  Y N 440 
PHE CD1  C  Y N 441 
PHE CD2  C  Y N 442 
PHE CE1  C  Y N 443 
PHE CE2  C  Y N 444 
PHE CZ   C  Y N 445 
PHE OXT  O  N N 446 
PHE H    H  N N 447 
PHE H2   H  N N 448 
PHE HA   H  N N 449 
PHE HB2  H  N N 450 
PHE HB3  H  N N 451 
PHE HD1  H  N N 452 
PHE HD2  H  N N 453 
PHE HE1  H  N N 454 
PHE HE2  H  N N 455 
PHE HZ   H  N N 456 
PHE HXT  H  N N 457 
PRO N    N  N N 458 
PRO CA   C  N S 459 
PRO C    C  N N 460 
PRO O    O  N N 461 
PRO CB   C  N N 462 
PRO CG   C  N N 463 
PRO CD   C  N N 464 
PRO OXT  O  N N 465 
PRO H    H  N N 466 
PRO HA   H  N N 467 
PRO HB2  H  N N 468 
PRO HB3  H  N N 469 
PRO HG2  H  N N 470 
PRO HG3  H  N N 471 
PRO HD2  H  N N 472 
PRO HD3  H  N N 473 
PRO HXT  H  N N 474 
SER N    N  N N 475 
SER CA   C  N S 476 
SER C    C  N N 477 
SER O    O  N N 478 
SER CB   C  N N 479 
SER OG   O  N N 480 
SER OXT  O  N N 481 
SER H    H  N N 482 
SER H2   H  N N 483 
SER HA   H  N N 484 
SER HB2  H  N N 485 
SER HB3  H  N N 486 
SER HG   H  N N 487 
SER HXT  H  N N 488 
THR N    N  N N 489 
THR CA   C  N S 490 
THR C    C  N N 491 
THR O    O  N N 492 
THR CB   C  N R 493 
THR OG1  O  N N 494 
THR CG2  C  N N 495 
THR OXT  O  N N 496 
THR H    H  N N 497 
THR H2   H  N N 498 
THR HA   H  N N 499 
THR HB   H  N N 500 
THR HG1  H  N N 501 
THR HG21 H  N N 502 
THR HG22 H  N N 503 
THR HG23 H  N N 504 
THR HXT  H  N N 505 
TRP N    N  N N 506 
TRP CA   C  N S 507 
TRP C    C  N N 508 
TRP O    O  N N 509 
TRP CB   C  N N 510 
TRP CG   C  Y N 511 
TRP CD1  C  Y N 512 
TRP CD2  C  Y N 513 
TRP NE1  N  Y N 514 
TRP CE2  C  Y N 515 
TRP CE3  C  Y N 516 
TRP CZ2  C  Y N 517 
TRP CZ3  C  Y N 518 
TRP CH2  C  Y N 519 
TRP OXT  O  N N 520 
TRP H    H  N N 521 
TRP H2   H  N N 522 
TRP HA   H  N N 523 
TRP HB2  H  N N 524 
TRP HB3  H  N N 525 
TRP HD1  H  N N 526 
TRP HE1  H  N N 527 
TRP HE3  H  N N 528 
TRP HZ2  H  N N 529 
TRP HZ3  H  N N 530 
TRP HH2  H  N N 531 
TRP HXT  H  N N 532 
TYR N    N  N N 533 
TYR CA   C  N S 534 
TYR C    C  N N 535 
TYR O    O  N N 536 
TYR CB   C  N N 537 
TYR CG   C  Y N 538 
TYR CD1  C  Y N 539 
TYR CD2  C  Y N 540 
TYR CE1  C  Y N 541 
TYR CE2  C  Y N 542 
TYR CZ   C  Y N 543 
TYR OH   O  N N 544 
TYR OXT  O  N N 545 
TYR H    H  N N 546 
TYR H2   H  N N 547 
TYR HA   H  N N 548 
TYR HB2  H  N N 549 
TYR HB3  H  N N 550 
TYR HD1  H  N N 551 
TYR HD2  H  N N 552 
TYR HE1  H  N N 553 
TYR HE2  H  N N 554 
TYR HH   H  N N 555 
TYR HXT  H  N N 556 
VAL N    N  N N 557 
VAL CA   C  N S 558 
VAL C    C  N N 559 
VAL O    O  N N 560 
VAL CB   C  N N 561 
VAL CG1  C  N N 562 
VAL CG2  C  N N 563 
VAL OXT  O  N N 564 
VAL H    H  N N 565 
VAL H2   H  N N 566 
VAL HA   H  N N 567 
VAL HB   H  N N 568 
VAL HG11 H  N N 569 
VAL HG12 H  N N 570 
VAL HG13 H  N N 571 
VAL HG21 H  N N 572 
VAL HG22 H  N N 573 
VAL HG23 H  N N 574 
VAL HXT  H  N N 575 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
GOL C1  O1   sing N N 129 
GOL C1  C2   sing N N 130 
GOL C1  H11  sing N N 131 
GOL C1  H12  sing N N 132 
GOL O1  HO1  sing N N 133 
GOL C2  O2   sing N N 134 
GOL C2  C3   sing N N 135 
GOL C2  H2   sing N N 136 
GOL O2  HO2  sing N N 137 
GOL C3  O3   sing N N 138 
GOL C3  H31  sing N N 139 
GOL C3  H32  sing N N 140 
GOL O3  HO3  sing N N 141 
HEM CHA C1A  sing N N 142 
HEM CHA C4D  doub N N 143 
HEM CHA HHA  sing N N 144 
HEM CHB C4A  sing N N 145 
HEM CHB C1B  doub N N 146 
HEM CHB HHB  sing N N 147 
HEM CHC C4B  sing N N 148 
HEM CHC C1C  doub N N 149 
HEM CHC HHC  sing N N 150 
HEM CHD C4C  doub N N 151 
HEM CHD C1D  sing N N 152 
HEM CHD HHD  sing N N 153 
HEM C1A C2A  doub Y N 154 
HEM C1A NA   sing Y N 155 
HEM C2A C3A  sing Y N 156 
HEM C2A CAA  sing N N 157 
HEM C3A C4A  doub Y N 158 
HEM C3A CMA  sing N N 159 
HEM C4A NA   sing Y N 160 
HEM CMA HMA  sing N N 161 
HEM CMA HMAA sing N N 162 
HEM CMA HMAB sing N N 163 
HEM CAA CBA  sing N N 164 
HEM CAA HAA  sing N N 165 
HEM CAA HAAA sing N N 166 
HEM CBA CGA  sing N N 167 
HEM CBA HBA  sing N N 168 
HEM CBA HBAA sing N N 169 
HEM CGA O1A  doub N N 170 
HEM CGA O2A  sing N N 171 
HEM C1B C2B  sing N N 172 
HEM C1B NB   sing N N 173 
HEM C2B C3B  doub N N 174 
HEM C2B CMB  sing N N 175 
HEM C3B C4B  sing N N 176 
HEM C3B CAB  sing N N 177 
HEM C4B NB   doub N N 178 
HEM CMB HMB  sing N N 179 
HEM CMB HMBA sing N N 180 
HEM CMB HMBB sing N N 181 
HEM CAB CBB  doub N N 182 
HEM CAB HAB  sing N N 183 
HEM CBB HBB  sing N N 184 
HEM CBB HBBA sing N N 185 
HEM C1C C2C  sing Y N 186 
HEM C1C NC   sing Y N 187 
HEM C2C C3C  doub Y N 188 
HEM C2C CMC  sing N N 189 
HEM C3C C4C  sing Y N 190 
HEM C3C CAC  sing N N 191 
HEM C4C NC   sing Y N 192 
HEM CMC HMC  sing N N 193 
HEM CMC HMCA sing N N 194 
HEM CMC HMCB sing N N 195 
HEM CAC CBC  doub N N 196 
HEM CAC HAC  sing N N 197 
HEM CBC HBC  sing N N 198 
HEM CBC HBCA sing N N 199 
HEM C1D C2D  sing N N 200 
HEM C1D ND   doub N N 201 
HEM C2D C3D  doub N N 202 
HEM C2D CMD  sing N N 203 
HEM C3D C4D  sing N N 204 
HEM C3D CAD  sing N N 205 
HEM C4D ND   sing N N 206 
HEM CMD HMD  sing N N 207 
HEM CMD HMDA sing N N 208 
HEM CMD HMDB sing N N 209 
HEM CAD CBD  sing N N 210 
HEM CAD HAD  sing N N 211 
HEM CAD HADA sing N N 212 
HEM CBD CGD  sing N N 213 
HEM CBD HBD  sing N N 214 
HEM CBD HBDA sing N N 215 
HEM CGD O1D  doub N N 216 
HEM CGD O2D  sing N N 217 
HEM O2A H2A  sing N N 218 
HEM O2D H2D  sing N N 219 
HEM FE  NA   sing N N 220 
HEM FE  NB   sing N N 221 
HEM FE  NC   sing N N 222 
HEM FE  ND   sing N N 223 
HIS N   CA   sing N N 224 
HIS N   H    sing N N 225 
HIS N   H2   sing N N 226 
HIS CA  C    sing N N 227 
HIS CA  CB   sing N N 228 
HIS CA  HA   sing N N 229 
HIS C   O    doub N N 230 
HIS C   OXT  sing N N 231 
HIS CB  CG   sing N N 232 
HIS CB  HB2  sing N N 233 
HIS CB  HB3  sing N N 234 
HIS CG  ND1  sing Y N 235 
HIS CG  CD2  doub Y N 236 
HIS ND1 CE1  doub Y N 237 
HIS ND1 HD1  sing N N 238 
HIS CD2 NE2  sing Y N 239 
HIS CD2 HD2  sing N N 240 
HIS CE1 NE2  sing Y N 241 
HIS CE1 HE1  sing N N 242 
HIS NE2 HE2  sing N N 243 
HIS OXT HXT  sing N N 244 
HOH O   H1   sing N N 245 
HOH O   H2   sing N N 246 
ILE N   CA   sing N N 247 
ILE N   H    sing N N 248 
ILE N   H2   sing N N 249 
ILE CA  C    sing N N 250 
ILE CA  CB   sing N N 251 
ILE CA  HA   sing N N 252 
ILE C   O    doub N N 253 
ILE C   OXT  sing N N 254 
ILE CB  CG1  sing N N 255 
ILE CB  CG2  sing N N 256 
ILE CB  HB   sing N N 257 
ILE CG1 CD1  sing N N 258 
ILE CG1 HG12 sing N N 259 
ILE CG1 HG13 sing N N 260 
ILE CG2 HG21 sing N N 261 
ILE CG2 HG22 sing N N 262 
ILE CG2 HG23 sing N N 263 
ILE CD1 HD11 sing N N 264 
ILE CD1 HD12 sing N N 265 
ILE CD1 HD13 sing N N 266 
ILE OXT HXT  sing N N 267 
LEU N   CA   sing N N 268 
LEU N   H    sing N N 269 
LEU N   H2   sing N N 270 
LEU CA  C    sing N N 271 
LEU CA  CB   sing N N 272 
LEU CA  HA   sing N N 273 
LEU C   O    doub N N 274 
LEU C   OXT  sing N N 275 
LEU CB  CG   sing N N 276 
LEU CB  HB2  sing N N 277 
LEU CB  HB3  sing N N 278 
LEU CG  CD1  sing N N 279 
LEU CG  CD2  sing N N 280 
LEU CG  HG   sing N N 281 
LEU CD1 HD11 sing N N 282 
LEU CD1 HD12 sing N N 283 
LEU CD1 HD13 sing N N 284 
LEU CD2 HD21 sing N N 285 
LEU CD2 HD22 sing N N 286 
LEU CD2 HD23 sing N N 287 
LEU OXT HXT  sing N N 288 
LYS N   CA   sing N N 289 
LYS N   H    sing N N 290 
LYS N   H2   sing N N 291 
LYS CA  C    sing N N 292 
LYS CA  CB   sing N N 293 
LYS CA  HA   sing N N 294 
LYS C   O    doub N N 295 
LYS C   OXT  sing N N 296 
LYS CB  CG   sing N N 297 
LYS CB  HB2  sing N N 298 
LYS CB  HB3  sing N N 299 
LYS CG  CD   sing N N 300 
LYS CG  HG2  sing N N 301 
LYS CG  HG3  sing N N 302 
LYS CD  CE   sing N N 303 
LYS CD  HD2  sing N N 304 
LYS CD  HD3  sing N N 305 
LYS CE  NZ   sing N N 306 
LYS CE  HE2  sing N N 307 
LYS CE  HE3  sing N N 308 
LYS NZ  HZ1  sing N N 309 
LYS NZ  HZ2  sing N N 310 
LYS NZ  HZ3  sing N N 311 
LYS OXT HXT  sing N N 312 
MET N   CA   sing N N 313 
MET N   H    sing N N 314 
MET N   H2   sing N N 315 
MET CA  C    sing N N 316 
MET CA  CB   sing N N 317 
MET CA  HA   sing N N 318 
MET C   O    doub N N 319 
MET C   OXT  sing N N 320 
MET CB  CG   sing N N 321 
MET CB  HB2  sing N N 322 
MET CB  HB3  sing N N 323 
MET CG  SD   sing N N 324 
MET CG  HG2  sing N N 325 
MET CG  HG3  sing N N 326 
MET SD  CE   sing N N 327 
MET CE  HE1  sing N N 328 
MET CE  HE2  sing N N 329 
MET CE  HE3  sing N N 330 
MET OXT HXT  sing N N 331 
OLA C1  O1   doub N N 332 
OLA C1  O2   sing N N 333 
OLA C1  C2   sing N N 334 
OLA O2  HO2  sing N N 335 
OLA C2  C3   sing N N 336 
OLA C2  H21  sing N N 337 
OLA C2  H22  sing N N 338 
OLA C3  C4   sing N N 339 
OLA C3  H31  sing N N 340 
OLA C3  H32  sing N N 341 
OLA C4  C5   sing N N 342 
OLA C4  H41  sing N N 343 
OLA C4  H42  sing N N 344 
OLA C5  C6   sing N N 345 
OLA C5  H51  sing N N 346 
OLA C5  H52  sing N N 347 
OLA C6  C7   sing N N 348 
OLA C6  H61  sing N N 349 
OLA C6  H62  sing N N 350 
OLA C7  C8   sing N N 351 
OLA C7  H71  sing N N 352 
OLA C7  H72  sing N N 353 
OLA C8  C9   sing N N 354 
OLA C8  H81  sing N N 355 
OLA C8  H82  sing N N 356 
OLA C9  C10  doub N Z 357 
OLA C9  H9   sing N N 358 
OLA C10 C11  sing N N 359 
OLA C10 H10  sing N N 360 
OLA C11 C12  sing N N 361 
OLA C11 H111 sing N N 362 
OLA C11 H112 sing N N 363 
OLA C12 C13  sing N N 364 
OLA C12 H121 sing N N 365 
OLA C12 H122 sing N N 366 
OLA C13 C14  sing N N 367 
OLA C13 H131 sing N N 368 
OLA C13 H132 sing N N 369 
OLA C14 C15  sing N N 370 
OLA C14 H141 sing N N 371 
OLA C14 H142 sing N N 372 
OLA C15 C16  sing N N 373 
OLA C15 H151 sing N N 374 
OLA C15 H152 sing N N 375 
OLA C16 C17  sing N N 376 
OLA C16 H161 sing N N 377 
OLA C16 H162 sing N N 378 
OLA C17 C18  sing N N 379 
OLA C17 H171 sing N N 380 
OLA C17 H172 sing N N 381 
OLA C18 H181 sing N N 382 
OLA C18 H182 sing N N 383 
OLA C18 H183 sing N N 384 
PEG C1  O1   sing N N 385 
PEG C1  C2   sing N N 386 
PEG C1  H11  sing N N 387 
PEG C1  H12  sing N N 388 
PEG O1  HO1  sing N N 389 
PEG C2  O2   sing N N 390 
PEG C2  H21  sing N N 391 
PEG C2  H22  sing N N 392 
PEG O2  C3   sing N N 393 
PEG C3  C4   sing N N 394 
PEG C3  H31  sing N N 395 
PEG C3  H32  sing N N 396 
PEG C4  O4   sing N N 397 
PEG C4  H41  sing N N 398 
PEG C4  H42  sing N N 399 
PEG O4  HO4  sing N N 400 
PGE C1  O1   sing N N 401 
PGE C1  C2   sing N N 402 
PGE C1  H1   sing N N 403 
PGE C1  H12  sing N N 404 
PGE O1  HO1  sing N N 405 
PGE C2  O2   sing N N 406 
PGE C2  H2   sing N N 407 
PGE C2  H22  sing N N 408 
PGE O2  C3   sing N N 409 
PGE C3  C4   sing N N 410 
PGE C3  H3   sing N N 411 
PGE C3  H32  sing N N 412 
PGE C4  O3   sing N N 413 
PGE C4  H4   sing N N 414 
PGE C4  H42  sing N N 415 
PGE O4  C6   sing N N 416 
PGE O4  HO4  sing N N 417 
PGE C6  C5   sing N N 418 
PGE C6  H6   sing N N 419 
PGE C6  H62  sing N N 420 
PGE C5  O3   sing N N 421 
PGE C5  H5   sing N N 422 
PGE C5  H52  sing N N 423 
PHE N   CA   sing N N 424 
PHE N   H    sing N N 425 
PHE N   H2   sing N N 426 
PHE CA  C    sing N N 427 
PHE CA  CB   sing N N 428 
PHE CA  HA   sing N N 429 
PHE C   O    doub N N 430 
PHE C   OXT  sing N N 431 
PHE CB  CG   sing N N 432 
PHE CB  HB2  sing N N 433 
PHE CB  HB3  sing N N 434 
PHE CG  CD1  doub Y N 435 
PHE CG  CD2  sing Y N 436 
PHE CD1 CE1  sing Y N 437 
PHE CD1 HD1  sing N N 438 
PHE CD2 CE2  doub Y N 439 
PHE CD2 HD2  sing N N 440 
PHE CE1 CZ   doub Y N 441 
PHE CE1 HE1  sing N N 442 
PHE CE2 CZ   sing Y N 443 
PHE CE2 HE2  sing N N 444 
PHE CZ  HZ   sing N N 445 
PHE OXT HXT  sing N N 446 
PRO N   CA   sing N N 447 
PRO N   CD   sing N N 448 
PRO N   H    sing N N 449 
PRO CA  C    sing N N 450 
PRO CA  CB   sing N N 451 
PRO CA  HA   sing N N 452 
PRO C   O    doub N N 453 
PRO C   OXT  sing N N 454 
PRO CB  CG   sing N N 455 
PRO CB  HB2  sing N N 456 
PRO CB  HB3  sing N N 457 
PRO CG  CD   sing N N 458 
PRO CG  HG2  sing N N 459 
PRO CG  HG3  sing N N 460 
PRO CD  HD2  sing N N 461 
PRO CD  HD3  sing N N 462 
PRO OXT HXT  sing N N 463 
SER N   CA   sing N N 464 
SER N   H    sing N N 465 
SER N   H2   sing N N 466 
SER CA  C    sing N N 467 
SER CA  CB   sing N N 468 
SER CA  HA   sing N N 469 
SER C   O    doub N N 470 
SER C   OXT  sing N N 471 
SER CB  OG   sing N N 472 
SER CB  HB2  sing N N 473 
SER CB  HB3  sing N N 474 
SER OG  HG   sing N N 475 
SER OXT HXT  sing N N 476 
THR N   CA   sing N N 477 
THR N   H    sing N N 478 
THR N   H2   sing N N 479 
THR CA  C    sing N N 480 
THR CA  CB   sing N N 481 
THR CA  HA   sing N N 482 
THR C   O    doub N N 483 
THR C   OXT  sing N N 484 
THR CB  OG1  sing N N 485 
THR CB  CG2  sing N N 486 
THR CB  HB   sing N N 487 
THR OG1 HG1  sing N N 488 
THR CG2 HG21 sing N N 489 
THR CG2 HG22 sing N N 490 
THR CG2 HG23 sing N N 491 
THR OXT HXT  sing N N 492 
TRP N   CA   sing N N 493 
TRP N   H    sing N N 494 
TRP N   H2   sing N N 495 
TRP CA  C    sing N N 496 
TRP CA  CB   sing N N 497 
TRP CA  HA   sing N N 498 
TRP C   O    doub N N 499 
TRP C   OXT  sing N N 500 
TRP CB  CG   sing N N 501 
TRP CB  HB2  sing N N 502 
TRP CB  HB3  sing N N 503 
TRP CG  CD1  doub Y N 504 
TRP CG  CD2  sing Y N 505 
TRP CD1 NE1  sing Y N 506 
TRP CD1 HD1  sing N N 507 
TRP CD2 CE2  doub Y N 508 
TRP CD2 CE3  sing Y N 509 
TRP NE1 CE2  sing Y N 510 
TRP NE1 HE1  sing N N 511 
TRP CE2 CZ2  sing Y N 512 
TRP CE3 CZ3  doub Y N 513 
TRP CE3 HE3  sing N N 514 
TRP CZ2 CH2  doub Y N 515 
TRP CZ2 HZ2  sing N N 516 
TRP CZ3 CH2  sing Y N 517 
TRP CZ3 HZ3  sing N N 518 
TRP CH2 HH2  sing N N 519 
TRP OXT HXT  sing N N 520 
TYR N   CA   sing N N 521 
TYR N   H    sing N N 522 
TYR N   H2   sing N N 523 
TYR CA  C    sing N N 524 
TYR CA  CB   sing N N 525 
TYR CA  HA   sing N N 526 
TYR C   O    doub N N 527 
TYR C   OXT  sing N N 528 
TYR CB  CG   sing N N 529 
TYR CB  HB2  sing N N 530 
TYR CB  HB3  sing N N 531 
TYR CG  CD1  doub Y N 532 
TYR CG  CD2  sing Y N 533 
TYR CD1 CE1  sing Y N 534 
TYR CD1 HD1  sing N N 535 
TYR CD2 CE2  doub Y N 536 
TYR CD2 HD2  sing N N 537 
TYR CE1 CZ   doub Y N 538 
TYR CE1 HE1  sing N N 539 
TYR CE2 CZ   sing Y N 540 
TYR CE2 HE2  sing N N 541 
TYR CZ  OH   sing N N 542 
TYR OH  HH   sing N N 543 
TYR OXT HXT  sing N N 544 
VAL N   CA   sing N N 545 
VAL N   H    sing N N 546 
VAL N   H2   sing N N 547 
VAL CA  C    sing N N 548 
VAL CA  CB   sing N N 549 
VAL CA  HA   sing N N 550 
VAL C   O    doub N N 551 
VAL C   OXT  sing N N 552 
VAL CB  CG1  sing N N 553 
VAL CB  CG2  sing N N 554 
VAL CB  HB   sing N N 555 
VAL CG1 HG11 sing N N 556 
VAL CG1 HG12 sing N N 557 
VAL CG1 HG13 sing N N 558 
VAL CG2 HG21 sing N N 559 
VAL CG2 HG22 sing N N 560 
VAL CG2 HG23 sing N N 561 
VAL OXT HXT  sing N N 562 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'Sao Paulo Research Foundation (FAPESP)' Brazil 2018/02865-2 1 
'Sao Paulo Research Foundation (FAPESP)' Brazil 2019/08855-1 2 
'Sao Paulo Research Foundation (FAPESP)' Brazil 2021/14410-2 3 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   8D8P 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    8W1K 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.006293 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.005870 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.008223 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C  
CL 
FE 
N  
O  
S  
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1     N  N   . PRO A 1 30  ? -23.038 -14.287 47.995  1.00 41.56  ? 9   PRO A N   1 
ATOM   2     C  CA  . PRO A 1 30  ? -21.653 -13.862 47.757  1.00 35.04  ? 9   PRO A CA  1 
ATOM   3     C  C   . PRO A 1 30  ? -21.593 -12.730 46.754  1.00 46.14  ? 9   PRO A C   1 
ATOM   4     O  O   . PRO A 1 30  ? -22.106 -12.866 45.641  1.00 30.27  ? 9   PRO A O   1 
ATOM   5     C  CB  . PRO A 1 30  ? -20.979 -15.120 47.187  1.00 37.13  ? 9   PRO A CB  1 
ATOM   6     C  CG  . PRO A 1 30  ? -21.870 -16.244 47.595  1.00 45.80  ? 9   PRO A CG  1 
ATOM   7     C  CD  . PRO A 1 30  ? -23.262 -15.673 47.553  1.00 37.29  ? 9   PRO A CD  1 
ATOM   8     N  N   . ARG A 1 31  ? -20.992 -11.613 47.147  1.00 43.22  ? 10  ARG A N   1 
ATOM   9     C  CA  . ARG A 1 31  ? -20.909 -10.443 46.290  1.00 45.09  ? 10  ARG A CA  1 
ATOM   10    C  C   . ARG A 1 31  ? -19.468 -9.967  46.209  1.00 43.91  ? 10  ARG A C   1 
ATOM   11    O  O   . ARG A 1 31  ? -18.678 -10.143 47.141  1.00 45.19  ? 10  ARG A O   1 
ATOM   12    C  CB  . ARG A 1 31  ? -21.795 -9.284  46.796  1.00 36.75  ? 10  ARG A CB  1 
ATOM   13    C  CG  . ARG A 1 31  ? -23.286 -9.466  46.611  1.00 52.93  ? 10  ARG A CG  1 
ATOM   14    C  CD  . ARG A 1 31  ? -24.023 -8.124  46.703  1.00 54.35  ? 10  ARG A CD  1 
ATOM   15    N  NE  . ARG A 1 31  ? -23.854 -7.314  45.501  1.00 59.34  ? 10  ARG A NE  1 
ATOM   16    C  CZ  . ARG A 1 31  ? -24.782 -7.161  44.562  1.00 59.22  ? 10  ARG A CZ  1 
ATOM   17    N  NH1 . ARG A 1 31  ? -25.988 -7.693  44.689  1.00 57.92  ? 10  ARG A NH1 1 
ATOM   18    N  NH2 . ARG A 1 31  ? -24.492 -6.457  43.467  1.00 55.14  ? 10  ARG A NH2 1 
ATOM   19    N  N   . VAL A 1 32  ? -19.133 -9.370  45.077  1.00 34.68  ? 11  VAL A N   1 
ATOM   20    C  CA  . VAL A 1 32  ? -17.909 -8.603  44.914  1.00 40.19  ? 11  VAL A CA  1 
ATOM   21    C  C   . VAL A 1 32  ? -18.333 -7.159  44.678  1.00 39.56  ? 11  VAL A C   1 
ATOM   22    O  O   . VAL A 1 32  ? -19.203 -6.895  43.842  1.00 37.48  ? 11  VAL A O   1 
ATOM   23    C  CB  . VAL A 1 32  ? -17.050 -9.166  43.763  1.00 45.04  ? 11  VAL A CB  1 
ATOM   24    C  CG1 . VAL A 1 32  ? -15.941 -8.242  43.431  1.00 36.22  ? 11  VAL A CG1 1 
ATOM   25    C  CG2 . VAL A 1 32  ? -16.484 -10.563 44.161  1.00 34.54  ? 11  VAL A CG2 1 
ATOM   26    N  N   . SER A 1 33  ? -17.759 -6.233  45.443  1.00 39.38  ? 12  SER A N   1 
ATOM   27    C  CA  . SER A 1 33  ? -18.231 -4.855  45.427  1.00 45.54  ? 12  SER A CA  1 
ATOM   28    C  C   . SER A 1 33  ? -17.674 -4.097  44.226  1.00 43.74  ? 12  SER A C   1 
ATOM   29    O  O   . SER A 1 33  ? -16.640 -4.452  43.648  1.00 42.41  ? 12  SER A O   1 
ATOM   30    C  CB  . SER A 1 33  ? -17.828 -4.130  46.712  1.00 45.56  ? 12  SER A CB  1 
ATOM   31    O  OG  . SER A 1 33  ? -16.420 -3.994  46.759  1.00 53.41  ? 12  SER A OG  1 
ATOM   32    N  N   . GLY A 1 34  ? -18.365 -3.024  43.870  1.00 44.53  ? 13  GLY A N   1 
ATOM   33    C  CA  . GLY A 1 34  ? -17.899 -2.143  42.821  1.00 49.41  ? 13  GLY A CA  1 
ATOM   34    C  C   . GLY A 1 34  ? -18.256 -2.667  41.448  1.00 46.65  ? 13  GLY A C   1 
ATOM   35    O  O   . GLY A 1 34  ? -18.881 -3.715  41.280  1.00 51.36  ? 13  GLY A O   1 
ATOM   36    N  N   . ASP A 1 35  ? -17.847 -1.909  40.441  1.00 49.52  ? 14  ASP A N   1 
ATOM   37    C  CA  . ASP A 1 35  ? -18.070 -2.285  39.054  1.00 43.43  ? 14  ASP A CA  1 
ATOM   38    C  C   . ASP A 1 35  ? -16.791 -2.904  38.520  1.00 38.20  ? 14  ASP A C   1 
ATOM   39    O  O   . ASP A 1 35  ? -15.734 -2.275  38.561  1.00 44.94  ? 14  ASP A O   1 
ATOM   40    C  CB  . ASP A 1 35  ? -18.490 -1.082  38.211  1.00 50.10  ? 14  ASP A CB  1 
ATOM   41    C  CG  . ASP A 1 35  ? -18.915 -1.486  36.811  1.00 53.79  ? 14  ASP A CG  1 
ATOM   42    O  OD1 . ASP A 1 35  ? -18.012 -1.793  36.014  1.00 48.04  ? 14  ASP A OD1 1 
ATOM   43    O  OD2 . ASP A 1 35  ? -20.142 -1.535  36.518  1.00 51.94  ? 14  ASP A OD2 1 
ATOM   44    N  N   . ARG A 1 36  ? -16.889 -4.133  38.019  1.00 39.92  ? 15  ARG A N   1 
ATOM   45    C  CA  . ARG A 1 36  ? -15.710 -4.899  37.637  1.00 33.99  ? 15  ARG A CA  1 
ATOM   46    C  C   . ARG A 1 36  ? -15.560 -5.004  36.128  1.00 37.67  ? 15  ARG A C   1 
ATOM   47    O  O   . ARG A 1 36  ? -14.866 -5.904  35.643  1.00 36.64  ? 15  ARG A O   1 
ATOM   48    C  CB  . ARG A 1 36  ? -15.756 -6.296  38.255  1.00 36.06  ? 15  ARG A CB  1 
ATOM   49    C  CG  . ARG A 1 36  ? -15.751 -6.271  39.751  1.00 37.44  ? 15  ARG A CG  1 
ATOM   50    C  CD  . ARG A 1 36  ? -14.449 -5.715  40.273  1.00 47.02  ? 15  ARG A CD  1 
ATOM   51    N  NE  . ARG A 1 36  ? -14.494 -5.520  41.716  1.00 48.81  ? 15  ARG A NE  1 
ATOM   52    C  CZ  . ARG A 1 36  ? -13.629 -6.041  42.583  1.00 60.65  ? 15  ARG A CZ  1 
ATOM   53    N  NH1 . ARG A 1 36  ? -12.627 -6.818  42.192  1.00 41.66  ? 15  ARG A NH1 1 
ATOM   54    N  NH2 . ARG A 1 36  ? -13.774 -5.776  43.880  1.00 54.50  ? 15  ARG A NH2 1 
ATOM   55    N  N   . THR A 1 37  ? -16.207 -4.103  35.376  1.00 35.42  ? 16  THR A N   1 
ATOM   56    C  CA  . THR A 1 37  ? -16.108 -4.153  33.916  1.00 39.19  ? 16  THR A CA  1 
ATOM   57    C  C   . THR A 1 37  ? -14.656 -4.117  33.452  1.00 38.39  ? 16  THR A C   1 
ATOM   58    O  O   . THR A 1 37  ? -14.254 -4.905  32.587  1.00 33.67  ? 16  THR A O   1 
ATOM   59    C  CB  . THR A 1 37  ? -16.899 -2.999  33.297  1.00 42.22  ? 16  THR A CB  1 
ATOM   60    O  OG1 . THR A 1 37  ? -18.230 -2.995  33.840  1.00 42.23  ? 16  THR A OG1 1 
ATOM   61    C  CG2 . THR A 1 37  ? -16.969 -3.149  31.762  1.00 37.12  ? 16  THR A CG2 1 
ATOM   62    N  N   . ILE A 1 38  ? -13.843 -3.223  34.032  1.00 33.84  ? 17  ILE A N   1 
ATOM   63    C  CA  . ILE A 1 38  ? -12.458 -3.108  33.578  1.00 34.53  ? 17  ILE A CA  1 
ATOM   64    C  C   . ILE A 1 38  ? -11.701 -4.401  33.831  1.00 35.58  ? 17  ILE A C   1 
ATOM   65    O  O   . ILE A 1 38  ? -10.797 -4.768  33.067  1.00 36.40  ? 17  ILE A O   1 
ATOM   66    C  CB  . ILE A 1 38  ? -11.762 -1.909  34.254  1.00 40.76  ? 17  ILE A CB  1 
ATOM   67    C  CG1 . ILE A 1 38  ? -12.445 -0.603  33.843  1.00 50.82  ? 17  ILE A CG1 1 
ATOM   68    C  CG2 . ILE A 1 38  ? -10.311 -1.848  33.840  1.00 42.37  ? 17  ILE A CG2 1 
ATOM   69    C  CD1 . ILE A 1 38  ? -11.683 0.639   34.274  1.00 46.79  ? 17  ILE A CD1 1 
ATOM   70    N  N   . GLN A 1 39  ? -12.065 -5.120  34.893  1.00 34.18  ? 18  GLN A N   1 
ATOM   71    C  CA  . GLN A 1 39  ? -11.369 -6.350  35.248  1.00 32.47  ? 18  GLN A CA  1 
ATOM   72    C  C   . GLN A 1 39  ? -11.646 -7.474  34.255  1.00 33.81  ? 18  GLN A C   1 
ATOM   73    O  O   . GLN A 1 39  ? -10.843 -8.407  34.155  1.00 39.47  ? 18  GLN A O   1 
ATOM   74    C  CB  . GLN A 1 39  ? -11.767 -6.756  36.683  1.00 31.92  ? 18  GLN A CB  1 
ATOM   75    C  CG  . GLN A 1 39  ? -10.809 -7.733  37.368  1.00 36.94  ? 18  GLN A CG  1 
ATOM   76    C  CD  . GLN A 1 39  ? -11.274 -8.145  38.760  1.00 44.36  ? 18  GLN A CD  1 
ATOM   77    O  OE1 . GLN A 1 39  ? -11.920 -7.370  39.477  1.00 40.23  ? 18  GLN A OE1 1 
ATOM   78    N  NE2 . GLN A 1 39  ? -10.929 -9.366  39.157  1.00 41.52  ? 18  GLN A NE2 1 
ATOM   79    N  N   . PHE A 1 40  ? -12.744 -7.411  33.492  1.00 39.41  ? 19  PHE A N   1 
ATOM   80    C  CA  . PHE A 1 40  ? -12.942 -8.419  32.452  1.00 35.85  ? 19  PHE A CA  1 
ATOM   81    C  C   . PHE A 1 40  ? -11.826 -8.358  31.419  1.00 47.29  ? 19  PHE A C   1 
ATOM   82    O  O   . PHE A 1 40  ? -11.316 -9.394  30.968  1.00 34.41  ? 19  PHE A O   1 
ATOM   83    C  CB  . PHE A 1 40  ? -14.308 -8.242  31.777  1.00 51.12  ? 19  PHE A CB  1 
ATOM   84    C  CG  . PHE A 1 40  ? -14.408 -8.900  30.397  1.00 71.75  ? 19  PHE A CG  1 
ATOM   85    C  CD1 . PHE A 1 40  ? -14.824 -10.227 30.265  1.00 75.28  ? 19  PHE A CD1 1 
ATOM   86    C  CD2 . PHE A 1 40  ? -14.093 -8.186  29.237  1.00 56.46  ? 19  PHE A CD2 1 
ATOM   87    C  CE1 . PHE A 1 40  ? -14.920 -10.829 29.001  1.00 50.77  ? 19  PHE A CE1 1 
ATOM   88    C  CE2 . PHE A 1 40  ? -14.175 -8.777  27.979  1.00 57.04  ? 19  PHE A CE2 1 
ATOM   89    C  CZ  . PHE A 1 40  ? -14.588 -10.099 27.859  1.00 61.24  ? 19  PHE A CZ  1 
ATOM   90    N  N   . LEU A 1 41  ? -11.420 -7.145  31.040  1.00 35.97  ? 20  LEU A N   1 
ATOM   91    C  CA  . LEU A 1 41  ? -10.383 -7.005  30.038  1.00 39.78  ? 20  LEU A CA  1 
ATOM   92    C  C   . LEU A 1 41  ? -9.012  -7.352  30.601  1.00 37.69  ? 20  LEU A C   1 
ATOM   93    O  O   . LEU A 1 41  ? -8.151  -7.864  29.879  1.00 46.42  ? 20  LEU A O   1 
ATOM   94    C  CB  . LEU A 1 41  ? -10.415 -5.581  29.481  1.00 44.20  ? 20  LEU A CB  1 
ATOM   95    C  CG  . LEU A 1 41  ? -10.049 -5.368  28.016  1.00 46.48  ? 20  LEU A CG  1 
ATOM   96    C  CD1 . LEU A 1 41  ? -10.786 -6.353  27.095  1.00 39.34  ? 20  LEU A CD1 1 
ATOM   97    C  CD2 . LEU A 1 41  ? -10.367 -3.914  27.646  1.00 39.49  ? 20  LEU A CD2 1 
ATOM   98    N  N   . THR A 1 42  ? -8.781  -7.096  31.885  1.00 29.67  ? 21  THR A N   1 
ATOM   99    C  CA  . THR A 1 42  ? -7.475  -7.429  32.422  1.00 36.19  ? 21  THR A CA  1 
ATOM   100   C  C   . THR A 1 42  ? -7.350  -8.919  32.755  1.00 37.63  ? 21  THR A C   1 
ATOM   101   O  O   . THR A 1 42  ? -6.254  -9.471  32.637  1.00 36.53  ? 21  THR A O   1 
ATOM   102   C  CB  . THR A 1 42  ? -7.193  -6.548  33.643  1.00 40.37  ? 21  THR A CB  1 
ATOM   103   O  OG1 . THR A 1 42  ? -7.951  -7.018  34.753  1.00 48.02  ? 21  THR A OG1 1 
ATOM   104   C  CG2 . THR A 1 42  ? -7.649  -5.138  33.373  1.00 36.76  ? 21  THR A CG2 1 
ATOM   105   N  N   . ASP A 1 43  ? -8.445  -9.583  33.169  1.00 27.83  ? 22  ASP A N   1 
ATOM   106   C  CA  . ASP A 1 43  ? -8.407  -10.965 33.637  1.00 29.36  ? 22  ASP A CA  1 
ATOM   107   C  C   . ASP A 1 43  ? -8.746  -12.001 32.564  1.00 26.44  ? 22  ASP A C   1 
ATOM   108   O  O   . ASP A 1 43  ? -8.365  -13.166 32.722  1.00 23.03  ? 22  ASP A O   1 
ATOM   109   C  CB  . ASP A 1 43  ? -9.388  -11.187 34.793  1.00 27.39  ? 22  ASP A CB  1 
ATOM   110   C  CG  . ASP A 1 43  ? -8.915  -10.571 36.110  1.00 42.60  ? 22  ASP A CG  1 
ATOM   111   O  OD1 . ASP A 1 43  ? -7.885  -9.860  36.113  1.00 41.84  ? 22  ASP A OD1 1 
ATOM   112   O  OD2 . ASP A 1 43  ? -9.597  -10.794 37.144  1.00 39.96  ? 22  ASP A OD2 1 
ATOM   113   N  N   . GLY A 1 44  ? -9.506  -11.632 31.531  1.00 26.38  ? 23  GLY A N   1 
ATOM   114   C  CA  . GLY A 1 44  ? -9.898  -12.593 30.502  1.00 25.67  ? 23  GLY A CA  1 
ATOM   115   C  C   . GLY A 1 44  ? -10.507 -13.866 31.063  1.00 22.43  ? 23  GLY A C   1 
ATOM   116   O  O   . GLY A 1 44  ? -11.513 -13.818 31.780  1.00 24.93  ? 23  GLY A O   1 
ATOM   117   N  N   . TYR A 1 45  ? -9.886  -15.018 30.764  1.00 20.68  ? 24  TYR A N   1 
ATOM   118   C  CA  . TYR A 1 45  ? -10.463 -16.276 31.200  1.00 21.42  ? 24  TYR A CA  1 
ATOM   119   C  C   . TYR A 1 45  ? -10.345 -16.461 32.705  1.00 24.69  ? 24  TYR A C   1 
ATOM   120   O  O   . TYR A 1 45  ? -11.047 -17.303 33.247  1.00 21.89  ? 24  TYR A O   1 
ATOM   121   C  CB  . TYR A 1 45  ? -9.783  -17.487 30.492  1.00 19.65  ? 24  TYR A CB  1 
ATOM   122   C  CG  . TYR A 1 45  ? -9.997  -17.495 28.992  1.00 17.75  ? 24  TYR A CG  1 
ATOM   123   C  CD1 . TYR A 1 45  ? -9.104  -16.827 28.140  1.00 21.38  ? 24  TYR A CD1 1 
ATOM   124   C  CD2 . TYR A 1 45  ? -11.126 -18.124 28.441  1.00 18.79  ? 24  TYR A CD2 1 
ATOM   125   C  CE1 . TYR A 1 45  ? -9.330  -16.787 26.779  1.00 20.74  ? 24  TYR A CE1 1 
ATOM   126   C  CE2 . TYR A 1 45  ? -11.355 -18.099 27.066  1.00 20.93  ? 24  TYR A CE2 1 
ATOM   127   C  CZ  . TYR A 1 45  ? -10.454 -17.436 26.249  1.00 20.25  ? 24  TYR A CZ  1 
ATOM   128   O  OH  . TYR A 1 45  ? -10.669 -17.401 24.889  1.00 20.21  ? 24  TYR A OH  1 
ATOM   129   N  N   . LEU A 1 46  ? -9.466  -15.706 33.387  1.00 26.70  ? 25  LEU A N   1 
ATOM   130   C  CA  . LEU A 1 46  ? -9.331  -15.809 34.840  1.00 24.47  ? 25  LEU A CA  1 
ATOM   131   C  C   . LEU A 1 46  ? -10.404 -15.047 35.601  1.00 27.46  ? 25  LEU A C   1 
ATOM   132   O  O   . LEU A 1 46  ? -10.477 -15.180 36.820  1.00 23.96  ? 25  LEU A O   1 
ATOM   133   C  CB  . LEU A 1 46  ? -7.970  -15.282 35.300  1.00 22.08  ? 25  LEU A CB  1 
ATOM   134   C  CG  . LEU A 1 46  ? -6.774  -15.879 34.542  1.00 23.13  ? 25  LEU A CG  1 
ATOM   135   C  CD1 . LEU A 1 46  ? -5.475  -15.279 35.084  1.00 27.02  ? 25  LEU A CD1 1 
ATOM   136   C  CD2 . LEU A 1 46  ? -6.793  -17.356 34.744  1.00 22.18  ? 25  LEU A CD2 1 
ATOM   137   N  N   . LEU A 1 47  ? -11.243 -14.260 34.926  1.00 25.70  ? 26  LEU A N   1 
ATOM   138   C  CA  . LEU A 1 47  ? -12.214 -13.439 35.647  1.00 22.44  ? 26  LEU A CA  1 
ATOM   139   C  C   . LEU A 1 47  ? -13.120 -14.238 36.583  1.00 22.78  ? 26  LEU A C   1 
ATOM   140   O  O   . LEU A 1 47  ? -13.219 -13.866 37.767  1.00 23.45  ? 26  LEU A O   1 
ATOM   141   C  CB  . LEU A 1 47  ? -13.025 -12.615 34.635  1.00 24.93  ? 26  LEU A CB  1 
ATOM   142   C  CG  . LEU A 1 47  ? -14.045 -11.555 35.113  1.00 27.39  ? 26  LEU A CG  1 
ATOM   143   C  CD1 . LEU A 1 47  ? -15.393 -12.181 35.458  1.00 40.30  ? 26  LEU A CD1 1 
ATOM   144   C  CD2 . LEU A 1 47  ? -13.479 -10.688 36.288  1.00 27.82  ? 26  LEU A CD2 1 
ATOM   145   N  N   . PRO A 1 48  ? -13.824 -15.290 36.152  1.00 21.85  ? 27  PRO A N   1 
ATOM   146   C  CA  . PRO A 1 48  ? -14.752 -15.935 37.108  1.00 23.45  ? 27  PRO A CA  1 
ATOM   147   C  C   . PRO A 1 48  ? -14.060 -16.512 38.333  1.00 26.46  ? 27  PRO A C   1 
ATOM   148   O  O   . PRO A 1 48  ? -14.584 -16.392 39.445  1.00 21.09  ? 27  PRO A O   1 
ATOM   149   C  CB  . PRO A 1 48  ? -15.424 -17.039 36.279  1.00 21.30  ? 27  PRO A CB  1 
ATOM   150   C  CG  . PRO A 1 48  ? -15.350 -16.519 34.852  1.00 22.62  ? 27  PRO A CG  1 
ATOM   151   C  CD  . PRO A 1 48  ? -13.989 -15.830 34.779  1.00 20.61  ? 27  PRO A CD  1 
ATOM   152   N  N   . SER A 1 49  ? -12.914 -17.169 38.172  1.00 23.17  ? 28  SER A N   1 
ATOM   153   C  CA  . SER A 1 49  ? -12.294 -17.755 39.363  1.00 19.68  ? 28  SER A CA  1 
ATOM   154   C  C   . SER A 1 49  ? -11.683 -16.663 40.250  1.00 23.06  ? 28  SER A C   1 
ATOM   155   O  O   . SER A 1 49  ? -11.704 -16.792 41.483  1.00 25.40  ? 28  SER A O   1 
ATOM   156   C  CB  . SER A 1 49  ? -11.270 -18.841 38.967  1.00 20.62  ? 28  SER A CB  1 
ATOM   157   O  OG  . SER A 1 49  ? -10.201 -18.353 38.199  1.00 23.66  ? 28  SER A OG  1 
ATOM   158   N  N   . ASN A 1 50  ? -11.227 -15.554 39.660  1.00 21.80  ? 29  ASN A N   1 
ATOM   159   C  CA  . ASN A 1 50  ? -10.800 -14.423 40.488  1.00 23.14  ? 29  ASN A CA  1 
ATOM   160   C  C   . ASN A 1 50  ? -11.955 -13.850 41.306  1.00 26.40  ? 29  ASN A C   1 
ATOM   161   O  O   . ASN A 1 50  ? -11.798 -13.559 42.497  1.00 26.22  ? 29  ASN A O   1 
ATOM   162   C  CB  . ASN A 1 50  ? -10.169 -13.333 39.635  1.00 27.01  ? 29  ASN A CB  1 
ATOM   163   C  CG  . ASN A 1 50  ? -8.678  -13.295 39.796  1.00 39.04  ? 29  ASN A CG  1 
ATOM   164   O  OD1 . ASN A 1 50  ? -8.152  -13.758 40.803  1.00 36.74  ? 29  ASN A OD1 1 
ATOM   165   N  ND2 . ASN A 1 50  ? -7.989  -12.753 38.817  1.00 41.13  ? 29  ASN A ND2 1 
ATOM   166   N  N   . LEU A 1 51  ? -13.138 -13.712 40.706  1.00 27.61  ? 30  LEU A N   1 
ATOM   167   C  CA  . LEU A 1 51  ? -14.258 -13.155 41.476  1.00 27.82  ? 30  LEU A CA  1 
ATOM   168   C  C   . LEU A 1 51  ? -14.758 -14.115 42.551  1.00 22.49  ? 30  LEU A C   1 
ATOM   169   O  O   . LEU A 1 51  ? -15.166 -13.673 43.625  1.00 25.76  ? 30  LEU A O   1 
ATOM   170   C  CB  . LEU A 1 51  ? -15.413 -12.783 40.551  1.00 24.78  ? 30  LEU A CB  1 
ATOM   171   C  CG  . LEU A 1 51  ? -15.037 -11.676 39.553  1.00 22.88  ? 30  LEU A CG  1 
ATOM   172   C  CD1 . LEU A 1 51  ? -16.260 -11.404 38.686  1.00 30.36  ? 30  LEU A CD1 1 
ATOM   173   C  CD2 . LEU A 1 51  ? -14.623 -10.403 40.294  1.00 28.88  ? 30  LEU A CD2 1 
ATOM   174   N  N   . ARG A 1 52  ? -14.809 -15.424 42.268  1.00 23.11  ? 31  ARG A N   1 
ATOM   175   C  CA  . ARG A 1 52  ? -15.201 -16.353 43.323  1.00 22.98  ? 31  ARG A CA  1 
ATOM   176   C  C   . ARG A 1 52  ? -14.224 -16.271 44.490  1.00 24.01  ? 31  ARG A C   1 
ATOM   177   O  O   . ARG A 1 52  ? -14.625 -16.340 45.665  1.00 26.26  ? 31  ARG A O   1 
ATOM   178   C  CB  . ARG A 1 52  ? -15.287 -17.791 42.797  1.00 24.09  ? 31  ARG A CB  1 
ATOM   179   C  CG  . ARG A 1 52  ? -16.516 -18.067 41.878  1.00 25.29  ? 31  ARG A CG  1 
ATOM   180   C  CD  . ARG A 1 52  ? -16.620 -19.611 41.641  1.00 26.41  ? 31  ARG A CD  1 
ATOM   181   N  NE  . ARG A 1 52  ? -15.597 -20.033 40.703  1.00 30.82  ? 31  ARG A NE  1 
ATOM   182   C  CZ  . ARG A 1 52  ? -15.736 -20.004 39.381  1.00 29.53  ? 31  ARG A CZ  1 
ATOM   183   N  NH1 . ARG A 1 52  ? -16.864 -19.604 38.806  1.00 25.07  ? 31  ARG A NH1 1 
ATOM   184   N  NH2 . ARG A 1 52  ? -14.720 -20.380 38.619  1.00 28.33  ? 31  ARG A NH2 1 
ATOM   185   N  N   . LYS A 1 53  ? -12.939 -16.115 44.186  1.00 22.34  ? 32  LYS A N   1 
ATOM   186   C  CA  . LYS A 1 53  ? -11.954 -16.020 45.258  1.00 21.52  ? 32  LYS A CA  1 
ATOM   187   C  C   . LYS A 1 53  ? -12.148 -14.717 46.041  1.00 25.69  ? 32  LYS A C   1 
ATOM   188   O  O   . LYS A 1 53  ? -12.152 -14.719 47.276  1.00 29.92  ? 32  LYS A O   1 
ATOM   189   C  CB  . LYS A 1 53  ? -10.544 -16.105 44.677  1.00 27.21  ? 32  LYS A CB  1 
ATOM   190   C  CG  . LYS A 1 53  ? -9.468  -15.740 45.690  1.00 29.80  ? 32  LYS A CG  1 
ATOM   191   C  CD  . LYS A 1 53  ? -8.075  -15.680 45.058  1.00 36.62  ? 32  LYS A CD  1 
ATOM   192   C  CE  . LYS A 1 53  ? -7.073  -15.191 46.102  1.00 46.96  ? 32  LYS A CE  1 
ATOM   193   N  NZ  . LYS A 1 53  ? -5.765  -14.808 45.501  1.00 62.12  ? 32  LYS A NZ  1 
ATOM   194   N  N   . THR A 1 54  ? -12.321 -13.596 45.331  1.00 26.88  ? 33  THR A N   1 
ATOM   195   C  CA  . THR A 1 54  ? -12.490 -12.309 45.999  1.00 26.34  ? 33  THR A CA  1 
ATOM   196   C  C   . THR A 1 54  ? -13.756 -12.300 46.828  1.00 35.17  ? 33  THR A C   1 
ATOM   197   O  O   . THR A 1 54  ? -13.837 -11.590 47.836  1.00 30.99  ? 33  THR A O   1 
ATOM   198   C  CB  . THR A 1 54  ? -12.505 -11.181 44.969  1.00 32.57  ? 33  THR A CB  1 
ATOM   199   O  OG1 . THR A 1 54  ? -11.236 -11.135 44.331  1.00 29.57  ? 33  THR A OG1 1 
ATOM   200   C  CG2 . THR A 1 54  ? -12.764 -9.803  45.624  1.00 30.86  ? 33  THR A CG2 1 
ATOM   201   N  N   . ALA A 1 55  ? -14.743 -13.098 46.442  1.00 25.66  ? 34  ALA A N   1 
ATOM   202   C  CA  . ALA A 1 55  ? -15.994 -13.159 47.181  1.00 30.43  ? 34  ALA A CA  1 
ATOM   203   C  C   . ALA A 1 55  ? -15.894 -14.008 48.434  1.00 34.22  ? 34  ALA A C   1 
ATOM   204   O  O   . ALA A 1 55  ? -16.853 -14.036 49.214  1.00 34.72  ? 34  ALA A O   1 
ATOM   205   C  CB  . ALA A 1 55  ? -17.129 -13.705 46.286  1.00 26.78  ? 34  ALA A CB  1 
ATOM   206   N  N   . GLY A 1 56  ? -14.787 -14.719 48.632  1.00 27.51  ? 35  GLY A N   1 
ATOM   207   C  CA  . GLY A 1 56  ? -14.643 -15.564 49.798  1.00 29.76  ? 35  GLY A CA  1 
ATOM   208   C  C   . GLY A 1 56  ? -15.139 -16.969 49.632  1.00 32.18  ? 35  GLY A C   1 
ATOM   209   O  O   . GLY A 1 56  ? -15.276 -17.684 50.631  1.00 32.88  ? 35  GLY A O   1 
ATOM   210   N  N   . LEU A 1 57  ? -15.433 -17.392 48.411  1.00 24.53  ? 36  LEU A N   1 
ATOM   211   C  CA  . LEU A 1 57  ? -15.878 -18.755 48.192  1.00 26.77  ? 36  LEU A CA  1 
ATOM   212   C  C   . LEU A 1 57  ? -14.698 -19.713 48.289  1.00 29.07  ? 36  LEU A C   1 
ATOM   213   O  O   . LEU A 1 57  ? -13.549 -19.341 48.034  1.00 28.80  ? 36  LEU A O   1 
ATOM   214   C  CB  . LEU A 1 57  ? -16.509 -18.886 46.808  1.00 26.85  ? 36  LEU A CB  1 
ATOM   215   C  CG  . LEU A 1 57  ? -17.834 -18.147 46.712  1.00 28.54  ? 36  LEU A CG  1 
ATOM   216   C  CD1 . LEU A 1 57  ? -18.388 -18.419 45.338  1.00 30.03  ? 36  LEU A CD1 1 
ATOM   217   C  CD2 . LEU A 1 57  ? -18.786 -18.625 47.809  1.00 28.64  ? 36  LEU A CD2 1 
ATOM   218   N  N   . GLU A 1 58  ? -14.990 -20.954 48.634  1.00 29.87  ? 37  GLU A N   1 
ATOM   219   C  CA  . GLU A 1 58  ? -13.919 -21.934 48.604  1.00 33.27  ? 37  GLU A CA  1 
ATOM   220   C  C   . GLU A 1 58  ? -13.671 -22.396 47.164  1.00 32.88  ? 37  GLU A C   1 
ATOM   221   O  O   . GLU A 1 58  ? -14.570 -22.332 46.310  1.00 28.83  ? 37  GLU A O   1 
ATOM   222   C  CB  . GLU A 1 58  ? -14.272 -23.125 49.496  1.00 34.35  ? 37  GLU A CB  1 
ATOM   223   C  CG  . GLU A 1 58  ? -14.059 -22.797 50.962  1.00 47.89  ? 37  GLU A CG  1 
ATOM   224   C  CD  . GLU A 1 58  ? -14.602 -23.854 51.902  1.00 67.27  ? 37  GLU A CD  1 
ATOM   225   O  OE1 . GLU A 1 58  ? -15.195 -24.840 51.412  1.00 60.31  ? 37  GLU A OE1 1 
ATOM   226   O  OE2 . GLU A 1 58  ? -14.433 -23.691 53.135  1.00 76.57  ? 37  GLU A OE2 1 
ATOM   227   N  N   . PRO A 1 59  ? -12.456 -22.839 46.844  1.00 28.98  ? 38  PRO A N   1 
ATOM   228   C  CA  . PRO A 1 59  ? -12.229 -23.406 45.513  1.00 25.75  ? 38  PRO A CA  1 
ATOM   229   C  C   . PRO A 1 59  ? -13.251 -24.503 45.275  1.00 32.98  ? 38  PRO A C   1 
ATOM   230   O  O   . PRO A 1 59  ? -13.676 -25.184 46.210  1.00 34.55  ? 38  PRO A O   1 
ATOM   231   C  CB  . PRO A 1 59  ? -10.799 -23.962 45.595  1.00 29.73  ? 38  PRO A CB  1 
ATOM   232   C  CG  . PRO A 1 59  ? -10.145 -23.138 46.649  1.00 28.02  ? 38  PRO A CG  1 
ATOM   233   C  CD  . PRO A 1 59  ? -11.232 -22.828 47.663  1.00 35.97  ? 38  PRO A CD  1 
ATOM   234   N  N   . GLU A 1 60  ? -13.706 -24.617 44.035  1.00 28.99  ? 39  GLU A N   1 
ATOM   235   C  CA  . GLU A 1 60  ? -14.674 -25.624 43.608  1.00 29.01  ? 39  GLU A CA  1 
ATOM   236   C  C   . GLU A 1 60  ? -16.097 -25.354 44.093  1.00 24.87  ? 39  GLU A C   1 
ATOM   237   O  O   . GLU A 1 60  ? -16.994 -26.193 43.866  1.00 28.68  ? 39  GLU A O   1 
ATOM   238   C  CB  . GLU A 1 60  ? -14.258 -27.042 44.027  1.00 31.78  ? 39  GLU A CB  1 
ATOM   239   C  CG  . GLU A 1 60  ? -12.801 -27.389 43.643  1.00 34.71  ? 39  GLU A CG  1 
ATOM   240   C  CD  . GLU A 1 60  ? -12.492 -27.298 42.139  1.00 55.52  ? 39  GLU A CD  1 
ATOM   241   O  OE1 . GLU A 1 60  ? -13.421 -27.260 41.257  1.00 32.67  ? 39  GLU A OE1 1 
ATOM   242   O  OE2 . GLU A 1 60  ? -11.275 -27.269 41.845  1.00 47.04  ? 39  GLU A OE2 1 
ATOM   243   N  N   . SER A 1 61  ? -16.360 -24.190 44.689  1.00 27.02  ? 40  SER A N   1 
ATOM   244   C  CA  . SER A 1 61  ? -17.716 -23.857 45.100  1.00 27.80  ? 40  SER A CA  1 
ATOM   245   C  C   . SER A 1 61  ? -18.664 -23.773 43.909  1.00 28.28  ? 40  SER A C   1 
ATOM   246   O  O   . SER A 1 61  ? -18.329 -23.215 42.864  1.00 28.58  ? 40  SER A O   1 
ATOM   247   C  CB  . SER A 1 61  ? -17.720 -22.509 45.832  1.00 29.24  ? 40  SER A CB  1 
ATOM   248   O  OG  . SER A 1 61  ? -19.040 -22.180 46.239  1.00 29.61  ? 40  SER A OG  1 
ATOM   249   N  N   . MET A 1 62  ? -19.883 -24.267 44.099  1.00 27.72  ? 41  MET A N   1 
ATOM   250   C  CA  . MET A 1 62  ? -20.932 -24.099 43.106  1.00 32.17  ? 41  MET A CA  1 
ATOM   251   C  C   . MET A 1 62  ? -21.881 -22.963 43.444  1.00 33.12  ? 41  MET A C   1 
ATOM   252   O  O   . MET A 1 62  ? -22.937 -22.849 42.813  1.00 32.38  ? 41  MET A O   1 
ATOM   253   C  CB  . MET A 1 62  ? -21.711 -25.405 42.926  1.00 33.01  ? 41  MET A CB  1 
ATOM   254   C  CG  . MET A 1 62  ? -20.770 -26.612 42.692  1.00 38.06  ? 41  MET A CG  1 
ATOM   255   S  SD  . MET A 1 62  ? -19.658 -26.435 41.255  1.00 42.10  ? 41  MET A SD  1 
ATOM   256   C  CE  . MET A 1 62  ? -20.748 -27.023 39.993  1.00 32.56  ? 41  MET A CE  1 
ATOM   257   N  N   A CYS A 1 63  ? -21.526 -22.104 44.413  0.39 30.42  ? 42  CYS A N   1 
ATOM   258   N  N   B CYS A 1 63  ? -21.522 -22.122 44.409  0.61 30.39  ? 42  CYS A N   1 
ATOM   259   C  CA  A CYS A 1 63  ? -22.358 -20.959 44.778  0.39 31.55  ? 42  CYS A CA  1 
ATOM   260   C  CA  B CYS A 1 63  ? -22.344 -20.969 44.742  0.61 31.59  ? 42  CYS A CA  1 
ATOM   261   C  C   A CYS A 1 63  ? -22.181 -19.827 43.762  0.39 28.60  ? 42  CYS A C   1 
ATOM   262   C  C   B CYS A 1 63  ? -22.195 -19.879 43.683  0.61 28.56  ? 42  CYS A C   1 
ATOM   263   O  O   A CYS A 1 63  ? -21.059 -19.549 43.328  0.39 27.87  ? 42  CYS A O   1 
ATOM   264   O  O   B CYS A 1 63  ? -21.096 -19.655 43.164  0.61 27.77  ? 42  CYS A O   1 
ATOM   265   C  CB  A CYS A 1 63  ? -21.998 -20.456 46.181  0.39 28.33  ? 42  CYS A CB  1 
ATOM   266   C  CB  B CYS A 1 63  ? -21.955 -20.390 46.098  0.61 28.16  ? 42  CYS A CB  1 
ATOM   267   S  SG  A CYS A 1 63  ? -23.229 -19.397 47.034  0.39 43.66  ? 42  CYS A SG  1 
ATOM   268   S  SG  B CYS A 1 63  ? -22.142 -21.509 47.488  0.61 36.89  ? 42  CYS A SG  1 
ATOM   269   N  N   . PRO A 1 64  ? -23.266 -19.155 43.382  1.00 28.40  ? 43  PRO A N   1 
ATOM   270   C  CA  . PRO A 1 64  ? -23.152 -18.016 42.460  1.00 28.59  ? 43  PRO A CA  1 
ATOM   271   C  C   . PRO A 1 64  ? -22.395 -16.859 43.092  1.00 30.43  ? 43  PRO A C   1 
ATOM   272   O  O   . PRO A 1 64  ? -22.362 -16.709 44.314  1.00 33.35  ? 43  PRO A O   1 
ATOM   273   C  CB  . PRO A 1 64  ? -24.616 -17.630 42.197  1.00 26.66  ? 43  PRO A CB  1 
ATOM   274   C  CG  . PRO A 1 64  ? -25.362 -18.100 43.428  1.00 42.58  ? 43  PRO A CG  1 
ATOM   275   C  CD  . PRO A 1 64  ? -24.642 -19.357 43.882  1.00 32.38  ? 43  PRO A CD  1 
ATOM   276   N  N   . VAL A 1 65  ? -21.777 -16.028 42.249  1.00 26.75  ? 44  VAL A N   1 
ATOM   277   C  CA  . VAL A 1 65  ? -21.135 -14.801 42.727  1.00 25.98  ? 44  VAL A CA  1 
ATOM   278   C  C   . VAL A 1 65  ? -21.694 -13.642 41.916  1.00 30.29  ? 44  VAL A C   1 
ATOM   279   O  O   . VAL A 1 65  ? -21.837 -13.746 40.690  1.00 24.68  ? 44  VAL A O   1 
ATOM   280   C  CB  . VAL A 1 65  ? -19.587 -14.867 42.630  1.00 29.79  ? 44  VAL A CB  1 
ATOM   281   C  CG1 . VAL A 1 65  ? -19.133 -15.254 41.248  1.00 34.66  ? 44  VAL A CG1 1 
ATOM   282   C  CG2 . VAL A 1 65  ? -18.961 -13.548 43.027  1.00 29.42  ? 44  VAL A CG2 1 
ATOM   283   N  N   . THR A 1 66  ? -22.020 -12.545 42.594  1.00 27.58  ? 45  THR A N   1 
ATOM   284   C  CA  . THR A 1 66  ? -22.646 -11.393 41.948  1.00 26.76  ? 45  THR A CA  1 
ATOM   285   C  C   . THR A 1 66  ? -21.745 -10.178 42.050  1.00 32.48  ? 45  THR A C   1 
ATOM   286   O  O   . THR A 1 66  ? -21.137 -9.932  43.098  1.00 31.81  ? 45  THR A O   1 
ATOM   287   C  CB  . THR A 1 66  ? -24.023 -11.081 42.559  1.00 30.80  ? 45  THR A CB  1 
ATOM   288   O  OG1 . THR A 1 66  ? -24.834 -12.248 42.488  1.00 32.53  ? 45  THR A OG1 1 
ATOM   289   C  CG2 . THR A 1 66  ? -24.720 -9.945  41.782  1.00 28.75  ? 45  THR A CG2 1 
ATOM   290   N  N   . THR A 1 67  ? -21.638 -9.445  40.940  1.00 27.33  ? 46  THR A N   1 
ATOM   291   C  CA  . THR A 1 67  ? -20.874 -8.208  40.865  1.00 30.71  ? 46  THR A CA  1 
ATOM   292   C  C   . THR A 1 67  ? -21.644 -7.235  39.969  1.00 27.25  ? 46  THR A C   1 
ATOM   293   O  O   . THR A 1 67  ? -22.783 -7.496  39.575  1.00 31.14  ? 46  THR A O   1 
ATOM   294   C  CB  . THR A 1 67  ? -19.443 -8.484  40.375  1.00 34.25  ? 46  THR A CB  1 
ATOM   295   O  OG1 . THR A 1 67  ? -18.639 -7.310  40.568  1.00 44.67  ? 46  THR A OG1 1 
ATOM   296   C  CG2 . THR A 1 67  ? -19.413 -8.900  38.900  1.00 34.17  ? 46  THR A CG2 1 
ATOM   297   N  N   . LYS A 1 68  ? -21.046 -6.090  39.664  1.00 29.81  ? 47  LYS A N   1 
ATOM   298   C  CA  . LYS A 1 68  ? -21.616 -5.172  38.690  1.00 33.76  ? 47  LYS A CA  1 
ATOM   299   C  C   . LYS A 1 68  ? -20.762 -5.203  37.438  1.00 32.08  ? 47  LYS A C   1 
ATOM   300   O  O   . LYS A 1 68  ? -19.537 -5.114  37.522  1.00 34.94  ? 47  LYS A O   1 
ATOM   301   C  CB  . LYS A 1 68  ? -21.705 -3.748  39.229  1.00 38.46  ? 47  LYS A CB  1 
ATOM   302   C  CG  . LYS A 1 68  ? -22.815 -3.562  40.269  1.00 47.92  ? 47  LYS A CG  1 
ATOM   303   C  CD  . LYS A 1 68  ? -23.379 -2.142  40.228  1.00 54.37  ? 47  LYS A CD  1 
ATOM   304   C  CE  . LYS A 1 68  ? -22.289 -1.097  39.961  1.00 64.10  ? 47  LYS A CE  1 
ATOM   305   N  NZ  . LYS A 1 68  ? -22.839 0.281   39.698  1.00 68.76  ? 47  LYS A NZ  1 
ATOM   306   N  N   . LEU A 1 69  ? -21.409 -5.346  36.289  1.00 31.23  ? 48  LEU A N   1 
ATOM   307   C  CA  . LEU A 1 69  ? -20.741 -5.270  35.000  1.00 36.83  ? 48  LEU A CA  1 
ATOM   308   C  C   . LEU A 1 69  ? -21.588 -4.363  34.130  1.00 30.66  ? 48  LEU A C   1 
ATOM   309   O  O   . LEU A 1 69  ? -22.816 -4.492  34.122  1.00 32.57  ? 48  LEU A O   1 
ATOM   310   C  CB  . LEU A 1 69  ? -20.572 -6.659  34.344  1.00 36.85  ? 48  LEU A CB  1 
ATOM   311   C  CG  . LEU A 1 69  ? -19.651 -7.659  35.078  1.00 52.87  ? 48  LEU A CG  1 
ATOM   312   C  CD1 . LEU A 1 69  ? -19.649 -9.046  34.435  1.00 39.92  ? 48  LEU A CD1 1 
ATOM   313   C  CD2 . LEU A 1 69  ? -18.201 -7.149  35.220  1.00 46.47  ? 48  LEU A CD2 1 
ATOM   314   N  N   . LEU A 1 70  ? -20.942 -3.413  33.458  1.00 39.26  ? 49  LEU A N   1 
ATOM   315   C  CA  . LEU A 1 70  ? -21.641 -2.491  32.559  1.00 41.99  ? 49  LEU A CA  1 
ATOM   316   C  C   . LEU A 1 70  ? -22.799 -1.793  33.268  1.00 39.78  ? 49  LEU A C   1 
ATOM   317   O  O   . LEU A 1 70  ? -23.887 -1.621  32.708  1.00 37.58  ? 49  LEU A O   1 
ATOM   318   C  CB  . LEU A 1 70  ? -22.139 -3.218  31.305  1.00 40.07  ? 49  LEU A CB  1 
ATOM   319   C  CG  . LEU A 1 70  ? -21.121 -3.579  30.213  1.00 39.73  ? 49  LEU A CG  1 
ATOM   320   C  CD1 . LEU A 1 70  ? -20.223 -2.390  29.863  1.00 46.62  ? 49  LEU A CD1 1 
ATOM   321   C  CD2 . LEU A 1 70  ? -20.293 -4.789  30.585  1.00 58.65  ? 49  LEU A CD2 1 
ATOM   322   N  N   . GLY A 1 71  ? -22.577 -1.421  34.529  1.00 36.09  ? 50  GLY A N   1 
ATOM   323   C  CA  . GLY A 1 71  ? -23.572 -0.695  35.290  1.00 38.52  ? 50  GLY A CA  1 
ATOM   324   C  C   . GLY A 1 71  ? -24.773 -1.473  35.788  1.00 45.80  ? 50  GLY A C   1 
ATOM   325   O  O   . GLY A 1 71  ? -25.715 -0.859  36.291  1.00 40.05  ? 50  GLY A O   1 
ATOM   326   N  N   . GLN A 1 72  ? -24.805 -2.795  35.655  1.00 33.88  ? 51  GLN A N   1 
ATOM   327   C  CA  . GLN A 1 72  ? -25.913 -3.579  36.194  1.00 29.61  ? 51  GLN A CA  1 
ATOM   328   C  C   . GLN A 1 72  ? -25.371 -4.812  36.897  1.00 29.81  ? 51  GLN A C   1 
ATOM   329   O  O   . GLN A 1 72  ? -24.250 -5.250  36.637  1.00 30.95  ? 51  GLN A O   1 
ATOM   330   C  CB  . GLN A 1 72  ? -26.894 -4.039  35.100  1.00 37.78  ? 51  GLN A CB  1 
ATOM   331   C  CG  . GLN A 1 72  ? -27.438 -2.922  34.228  1.00 45.77  ? 51  GLN A CG  1 
ATOM   332   C  CD  . GLN A 1 72  ? -28.281 -3.466  33.090  1.00 54.78  ? 51  GLN A CD  1 
ATOM   333   O  OE1 . GLN A 1 72  ? -27.762 -3.780  32.009  1.00 47.01  ? 51  GLN A OE1 1 
ATOM   334   N  NE2 . GLN A 1 72  ? -29.584 -3.610  33.335  1.00 43.27  ? 51  GLN A NE2 1 
ATOM   335   N  N   . ASP A 1 73  ? -26.207 -5.404  37.747  1.00 29.09  ? 52  ASP A N   1 
ATOM   336   C  CA  . ASP A 1 73  ? -25.820 -6.648  38.390  1.00 29.08  ? 52  ASP A CA  1 
ATOM   337   C  C   . ASP A 1 73  ? -25.559 -7.739  37.354  1.00 27.59  ? 52  ASP A C   1 
ATOM   338   O  O   . ASP A 1 73  ? -26.173 -7.778  36.278  1.00 24.05  ? 52  ASP A O   1 
ATOM   339   C  CB  . ASP A 1 73  ? -26.902 -7.113  39.368  1.00 31.05  ? 52  ASP A CB  1 
ATOM   340   C  CG  . ASP A 1 73  ? -26.809 -6.401  40.724  1.00 52.48  ? 52  ASP A CG  1 
ATOM   341   O  OD1 . ASP A 1 73  ? -25.880 -5.578  40.896  1.00 45.06  ? 52  ASP A OD1 1 
ATOM   342   O  OD2 . ASP A 1 73  ? -27.646 -6.674  41.614  1.00 57.31  ? 52  ASP A OD2 1 
ATOM   343   N  N   . ALA A 1 74  ? -24.633 -8.634  37.700  1.00 26.16  ? 53  ALA A N   1 
ATOM   344   C  CA  . ALA A 1 74  ? -24.348 -9.830  36.917  1.00 23.35  ? 53  ALA A CA  1 
ATOM   345   C  C   . ALA A 1 74  ? -23.998 -10.934 37.891  1.00 31.88  ? 53  ALA A C   1 
ATOM   346   O  O   . ALA A 1 74  ? -23.121 -10.759 38.740  1.00 27.14  ? 53  ALA A O   1 
ATOM   347   C  CB  . ALA A 1 74  ? -23.192 -9.604  35.943  1.00 23.13  ? 53  ALA A CB  1 
ATOM   348   N  N   . THR A 1 75  ? -24.669 -12.062 37.773  1.00 22.70  ? 54  THR A N   1 
ATOM   349   C  CA  . THR A 1 75  ? -24.423 -13.191 38.650  1.00 23.73  ? 54  THR A CA  1 
ATOM   350   C  C   . THR A 1 75  ? -23.760 -14.284 37.823  1.00 24.18  ? 54  THR A C   1 
ATOM   351   O  O   . THR A 1 75  ? -24.292 -14.668 36.779  1.00 23.17  ? 54  THR A O   1 
ATOM   352   C  CB  . THR A 1 75  ? -25.742 -13.660 39.244  1.00 23.42  ? 54  THR A CB  1 
ATOM   353   O  OG1 . THR A 1 75  ? -26.276 -12.594 40.043  1.00 23.24  ? 54  THR A OG1 1 
ATOM   354   C  CG2 . THR A 1 75  ? -25.550 -14.870 40.105  1.00 27.36  ? 54  THR A CG2 1 
ATOM   355   N  N   . ILE A 1 76  ? -22.617 -14.781 38.280  1.00 24.13  ? 55  ILE A N   1 
ATOM   356   C  CA  . ILE A 1 76  ? -21.856 -15.781 37.530  1.00 23.57  ? 55  ILE A CA  1 
ATOM   357   C  C   . ILE A 1 76  ? -22.122 -17.145 38.148  1.00 25.81  ? 55  ILE A C   1 
ATOM   358   O  O   . ILE A 1 76  ? -21.929 -17.327 39.356  1.00 25.58  ? 55  ILE A O   1 
ATOM   359   C  CB  . ILE A 1 76  ? -20.350 -15.453 37.528  1.00 23.43  ? 55  ILE A CB  1 
ATOM   360   C  CG1 . ILE A 1 76  ? -20.090 -14.096 36.911  1.00 24.57  ? 55  ILE A CG1 1 
ATOM   361   C  CG2 . ILE A 1 76  ? -19.565 -16.472 36.700  1.00 22.24  ? 55  ILE A CG2 1 
ATOM   362   C  CD1 . ILE A 1 76  ? -18.641 -13.730 36.900  1.00 30.98  ? 55  ILE A CD1 1 
ATOM   363   N  N   . VAL A 1 77  ? -22.536 -18.115 37.308  1.00 22.41  ? 56  VAL A N   1 
ATOM   364   C  CA  . VAL A 1 77  ? -22.927 -19.465 37.715  1.00 21.62  ? 56  VAL A CA  1 
ATOM   365   C  C   . VAL A 1 77  ? -22.117 -20.473 36.891  1.00 18.79  ? 56  VAL A C   1 
ATOM   366   O  O   . VAL A 1 77  ? -21.625 -20.155 35.800  1.00 22.41  ? 56  VAL A O   1 
ATOM   367   C  CB  . VAL A 1 77  ? -24.451 -19.698 37.534  1.00 24.66  ? 56  VAL A CB  1 
ATOM   368   C  CG1 . VAL A 1 77  ? -25.249 -18.564 38.236  1.00 24.36  ? 56  VAL A CG1 1 
ATOM   369   C  CG2 . VAL A 1 77  ? -24.835 -19.720 36.026  1.00 21.64  ? 56  VAL A CG2 1 
ATOM   370   N  N   . ARG A 1 78  ? -21.930 -21.673 37.445  1.00 23.43  ? 57  ARG A N   1 
ATOM   371   C  CA  . ARG A 1 78  ? -21.242 -22.732 36.701  1.00 24.83  ? 57  ARG A CA  1 
ATOM   372   C  C   . ARG A 1 78  ? -21.813 -24.081 37.111  1.00 27.69  ? 57  ARG A C   1 
ATOM   373   O  O   . ARG A 1 78  ? -22.515 -24.192 38.112  1.00 31.60  ? 57  ARG A O   1 
ATOM   374   C  CB  . ARG A 1 78  ? -19.716 -22.673 36.900  1.00 25.41  ? 57  ARG A CB  1 
ATOM   375   C  CG  . ARG A 1 78  ? -19.261 -22.657 38.320  1.00 29.66  ? 57  ARG A CG  1 
ATOM   376   C  CD  . ARG A 1 78  ? -18.527 -23.907 38.656  1.00 31.58  ? 57  ARG A CD  1 
ATOM   377   N  NE  . ARG A 1 78  ? -17.788 -23.720 39.899  1.00 31.68  ? 57  ARG A NE  1 
ATOM   378   C  CZ  . ARG A 1 78  ? -16.469 -23.762 40.007  1.00 29.35  ? 57  ARG A CZ  1 
ATOM   379   N  NH1 . ARG A 1 78  ? -15.696 -24.038 38.966  1.00 24.62  ? 57  ARG A NH1 1 
ATOM   380   N  NH2 . ARG A 1 78  ? -15.911 -23.528 41.192  1.00 26.35  ? 57  ARG A NH2 1 
ATOM   381   N  N   . GLY A 1 79  ? -21.528 -25.123 36.310  1.00 23.63  ? 58  GLY A N   1 
ATOM   382   C  CA  . GLY A 1 79  ? -22.000 -26.451 36.662  1.00 22.56  ? 58  GLY A CA  1 
ATOM   383   C  C   . GLY A 1 79  ? -23.420 -26.717 36.188  1.00 25.70  ? 58  GLY A C   1 
ATOM   384   O  O   . GLY A 1 79  ? -24.093 -25.876 35.579  1.00 25.55  ? 58  GLY A O   1 
ATOM   385   N  N   . SER A 1 80  ? -23.872 -27.936 36.482  1.00 27.74  ? 59  SER A N   1 
ATOM   386   C  CA  . SER A 1 80  ? -25.140 -28.431 35.943  1.00 20.86  ? 59  SER A CA  1 
ATOM   387   C  C   . SER A 1 80  ? -26.321 -27.569 36.360  1.00 24.73  ? 59  SER A C   1 
ATOM   388   O  O   . SER A 1 80  ? -27.214 -27.300 35.542  1.00 26.29  ? 59  SER A O   1 
ATOM   389   C  CB  . SER A 1 80  ? -25.360 -29.879 36.384  1.00 28.32  ? 59  SER A CB  1 
ATOM   390   O  OG  . SER A 1 80  ? -24.369 -30.673 35.756  1.00 36.53  ? 59  SER A OG  1 
ATOM   391   N  N   . ALA A 1 81  ? -26.366 -27.148 37.625  1.00 24.73  ? 60  ALA A N   1 
ATOM   392   C  CA  . ALA A 1 81  ? -27.486 -26.306 38.052  1.00 28.74  ? 60  ALA A CA  1 
ATOM   393   C  C   . ALA A 1 81  ? -27.426 -24.941 37.370  1.00 24.19  ? 60  ALA A C   1 
ATOM   394   O  O   . ALA A 1 81  ? -28.460 -24.378 36.984  1.00 25.71  ? 60  ALA A O   1 
ATOM   395   C  CB  . ALA A 1 81  ? -27.492 -26.159 39.577  1.00 27.82  ? 60  ALA A CB  1 
ATOM   396   N  N   . GLY A 1 82  ? -26.220 -24.415 37.189  1.00 20.13  ? 61  GLY A N   1 
ATOM   397   C  CA  . GLY A 1 82  ? -26.065 -23.153 36.485  1.00 24.74  ? 61  GLY A CA  1 
ATOM   398   C  C   . GLY A 1 82  ? -26.490 -23.271 35.032  1.00 25.20  ? 61  GLY A C   1 
ATOM   399   O  O   . GLY A 1 82  ? -27.077 -22.336 34.465  1.00 21.94  ? 61  GLY A O   1 
ATOM   400   N  N   . ILE A 1 83  ? -26.208 -24.427 34.412  1.00 21.55  ? 62  ILE A N   1 
ATOM   401   C  CA  . ILE A 1 83  ? -26.633 -24.669 33.033  1.00 22.53  ? 62  ILE A CA  1 
ATOM   402   C  C   . ILE A 1 83  ? -28.157 -24.655 32.947  1.00 25.94  ? 62  ILE A C   1 
ATOM   403   O  O   . ILE A 1 83  ? -28.750 -24.012 32.069  1.00 22.25  ? 62  ILE A O   1 
ATOM   404   C  CB  . ILE A 1 83  ? -26.027 -25.997 32.504  1.00 18.74  ? 62  ILE A CB  1 
ATOM   405   C  CG1 . ILE A 1 83  ? -24.530 -25.815 32.220  1.00 21.95  ? 62  ILE A CG1 1 
ATOM   406   C  CG2 . ILE A 1 83  ? -26.756 -26.474 31.239  1.00 22.49  ? 62  ILE A CG2 1 
ATOM   407   C  CD1 . ILE A 1 83  ? -23.725 -27.217 32.204  1.00 23.59  ? 62  ILE A CD1 1 
ATOM   408   N  N   . ASP A 1 84  ? -28.817 -25.342 33.877  1.00 24.68  ? 63  ASP A N   1 
ATOM   409   C  CA  . ASP A 1 84  ? -30.271 -25.407 33.835  1.00 22.24  ? 63  ASP A CA  1 
ATOM   410   C  C   . ASP A 1 84  ? -30.894 -24.031 33.960  1.00 27.75  ? 63  ASP A C   1 
ATOM   411   O  O   . ASP A 1 84  ? -31.901 -23.746 33.299  1.00 25.12  ? 63  ASP A O   1 
ATOM   412   C  CB  . ASP A 1 84  ? -30.796 -26.303 34.952  1.00 25.33  ? 63  ASP A CB  1 
ATOM   413   C  CG  . ASP A 1 84  ? -30.502 -27.776 34.710  1.00 37.10  ? 63  ASP A CG  1 
ATOM   414   O  OD1 . ASP A 1 84  ? -30.238 -28.149 33.544  1.00 34.67  ? 63  ASP A OD1 1 
ATOM   415   O  OD2 . ASP A 1 84  ? -30.579 -28.555 35.687  1.00 36.37  ? 63  ASP A OD2 1 
ATOM   416   N  N   . LEU A 1 85  ? -30.310 -23.162 34.795  1.00 21.45  ? 64  LEU A N   1 
ATOM   417   C  CA  . LEU A 1 85  ? -30.816 -21.793 34.921  1.00 22.87  ? 64  LEU A CA  1 
ATOM   418   C  C   . LEU A 1 85  ? -30.608 -21.007 33.638  1.00 25.95  ? 64  LEU A C   1 
ATOM   419   O  O   . LEU A 1 85  ? -31.539 -20.376 33.118  1.00 24.83  ? 64  LEU A O   1 
ATOM   420   C  CB  . LEU A 1 85  ? -30.138 -21.075 36.091  1.00 21.69  ? 64  LEU A CB  1 
ATOM   421   C  CG  . LEU A 1 85  ? -30.414 -19.563 36.173  1.00 27.38  ? 64  LEU A CG  1 
ATOM   422   C  CD1 . LEU A 1 85  ? -31.857 -19.334 36.683  1.00 32.65  ? 64  LEU A CD1 1 
ATOM   423   C  CD2 . LEU A 1 85  ? -29.410 -18.840 37.047  1.00 31.36  ? 64  LEU A CD2 1 
ATOM   424   N  N   . PHE A 1 86  ? -29.383 -21.021 33.127  1.00 22.29  ? 65  PHE A N   1 
ATOM   425   C  CA  . PHE A 1 86  ? -29.011 -20.215 31.972  1.00 20.42  ? 65  PHE A CA  1 
ATOM   426   C  C   . PHE A 1 86  ? -29.894 -20.524 30.765  1.00 21.62  ? 65  PHE A C   1 
ATOM   427   O  O   . PHE A 1 86  ? -30.293 -19.619 30.029  1.00 22.35  ? 65  PHE A O   1 
ATOM   428   C  CB  . PHE A 1 86  ? -27.526 -20.471 31.648  1.00 21.21  ? 65  PHE A CB  1 
ATOM   429   C  CG  . PHE A 1 86  ? -26.932 -19.494 30.671  1.00 20.60  ? 65  PHE A CG  1 
ATOM   430   C  CD1 . PHE A 1 86  ? -26.629 -18.204 31.072  1.00 21.73  ? 65  PHE A CD1 1 
ATOM   431   C  CD2 . PHE A 1 86  ? -26.624 -19.877 29.378  1.00 21.49  ? 65  PHE A CD2 1 
ATOM   432   C  CE1 . PHE A 1 86  ? -26.061 -17.289 30.191  1.00 20.51  ? 65  PHE A CE1 1 
ATOM   433   C  CE2 . PHE A 1 86  ? -26.015 -18.970 28.474  1.00 23.73  ? 65  PHE A CE2 1 
ATOM   434   C  CZ  . PHE A 1 86  ? -25.755 -17.659 28.881  1.00 22.19  ? 65  PHE A CZ  1 
ATOM   435   N  N   . TYR A 1 87  ? -30.253 -21.791 30.569  1.00 20.07  ? 66  TYR A N   1 
ATOM   436   C  CA  . TYR A 1 87  ? -31.016 -22.222 29.409  1.00 23.95  ? 66  TYR A CA  1 
ATOM   437   C  C   . TYR A 1 87  ? -32.507 -22.310 29.697  1.00 24.48  ? 66  TYR A C   1 
ATOM   438   O  O   . TYR A 1 87  ? -33.255 -22.866 28.891  1.00 24.11  ? 66  TYR A O   1 
ATOM   439   C  CB  . TYR A 1 87  ? -30.469 -23.574 28.888  1.00 19.23  ? 66  TYR A CB  1 
ATOM   440   C  CG  . TYR A 1 87  ? -29.137 -23.349 28.220  1.00 18.96  ? 66  TYR A CG  1 
ATOM   441   C  CD1 . TYR A 1 87  ? -29.074 -22.768 26.949  1.00 21.28  ? 66  TYR A CD1 1 
ATOM   442   C  CD2 . TYR A 1 87  ? -27.937 -23.642 28.865  1.00 20.87  ? 66  TYR A CD2 1 
ATOM   443   C  CE1 . TYR A 1 87  ? -27.854 -22.496 26.337  1.00 21.58  ? 66  TYR A CE1 1 
ATOM   444   C  CE2 . TYR A 1 87  ? -26.713 -23.381 28.259  1.00 21.42  ? 66  TYR A CE2 1 
ATOM   445   C  CZ  . TYR A 1 87  ? -26.673 -22.800 27.002  1.00 19.31  ? 66  TYR A CZ  1 
ATOM   446   O  OH  . TYR A 1 87  ? -25.458 -22.519 26.390  1.00 20.15  ? 66  TYR A OH  1 
ATOM   447   N  N   . ASP A 1 88  ? -32.964 -21.737 30.804  1.00 18.93  ? 67  ASP A N   1 
ATOM   448   C  CA  . ASP A 1 88  ? -34.406 -21.741 31.106  1.00 20.16  ? 67  ASP A CA  1 
ATOM   449   C  C   . ASP A 1 88  ? -35.009 -20.501 30.451  1.00 22.82  ? 67  ASP A C   1 
ATOM   450   O  O   . ASP A 1 88  ? -34.926 -19.391 30.987  1.00 22.78  ? 67  ASP A O   1 
ATOM   451   C  CB  . ASP A 1 88  ? -34.632 -21.769 32.610  1.00 24.67  ? 67  ASP A CB  1 
ATOM   452   C  CG  . ASP A 1 88  ? -36.103 -21.838 32.977  1.00 28.64  ? 67  ASP A CG  1 
ATOM   453   O  OD1 . ASP A 1 88  ? -36.960 -21.726 32.068  1.00 27.53  ? 67  ASP A OD1 1 
ATOM   454   O  OD2 . ASP A 1 88  ? -36.396 -22.019 34.176  1.00 31.78  ? 67  ASP A OD2 1 
ATOM   455   N  N   . GLU A 1 89  ? -35.612 -20.680 29.276  1.00 21.82  ? 68  GLU A N   1 
ATOM   456   C  CA  . GLU A 1 89  ? -36.133 -19.532 28.543  1.00 23.68  ? 68  GLU A CA  1 
ATOM   457   C  C   . GLU A 1 89  ? -37.413 -18.959 29.144  1.00 28.00  ? 68  GLU A C   1 
ATOM   458   O  O   . GLU A 1 89  ? -37.897 -17.938 28.649  1.00 25.47  ? 68  GLU A O   1 
ATOM   459   C  CB  . GLU A 1 89  ? -36.368 -19.913 27.068  1.00 24.82  ? 68  GLU A CB  1 
ATOM   460   C  CG  . GLU A 1 89  ? -35.020 -20.161 26.337  1.00 26.87  ? 68  GLU A CG  1 
ATOM   461   C  CD  . GLU A 1 89  ? -35.152 -20.327 24.820  1.00 36.79  ? 68  GLU A CD  1 
ATOM   462   O  OE1 . GLU A 1 89  ? -36.292 -20.289 24.305  1.00 34.59  ? 68  GLU A OE1 1 
ATOM   463   O  OE2 . GLU A 1 89  ? -34.105 -20.503 24.134  1.00 31.70  ? 68  GLU A OE2 1 
ATOM   464   N  N   . ASP A 1 90  ? -37.970 -19.586 30.169  1.00 26.22  ? 69  ASP A N   1 
ATOM   465   C  CA  . ASP A 1 90  ? -39.033 -18.939 30.932  1.00 29.95  ? 69  ASP A CA  1 
ATOM   466   C  C   . ASP A 1 90  ? -38.515 -17.758 31.743  1.00 30.36  ? 69  ASP A C   1 
ATOM   467   O  O   . ASP A 1 90  ? -39.305 -16.870 32.089  1.00 27.39  ? 69  ASP A O   1 
ATOM   468   C  CB  . ASP A 1 90  ? -39.698 -19.940 31.887  1.00 31.81  ? 69  ASP A CB  1 
ATOM   469   C  CG  . ASP A 1 90  ? -40.487 -21.021 31.164  1.00 50.86  ? 69  ASP A CG  1 
ATOM   470   O  OD1 . ASP A 1 90  ? -40.905 -20.793 30.008  1.00 53.21  ? 69  ASP A OD1 1 
ATOM   471   O  OD2 . ASP A 1 90  ? -40.694 -22.096 31.767  1.00 53.99  ? 69  ASP A OD2 1 
ATOM   472   N  N   . VAL A 1 91  ? -37.225 -17.740 32.093  1.00 25.71  ? 70  VAL A N   1 
ATOM   473   C  CA  . VAL A 1 91  ? -36.691 -16.667 32.938  1.00 25.57  ? 70  VAL A CA  1 
ATOM   474   C  C   . VAL A 1 91  ? -35.487 -15.962 32.328  1.00 23.50  ? 70  VAL A C   1 
ATOM   475   O  O   . VAL A 1 91  ? -35.064 -14.922 32.841  1.00 26.80  ? 70  VAL A O   1 
ATOM   476   C  CB  . VAL A 1 91  ? -36.320 -17.172 34.346  1.00 26.97  ? 70  VAL A CB  1 
ATOM   477   C  CG1 . VAL A 1 91  ? -37.581 -17.590 35.146  1.00 31.56  ? 70  VAL A CG1 1 
ATOM   478   C  CG2 . VAL A 1 91  ? -35.299 -18.325 34.284  1.00 26.36  ? 70  VAL A CG2 1 
ATOM   479   N  N   . MET A 1 92  ? -34.912 -16.504 31.255  1.00 22.37  ? 71  MET A N   1 
ATOM   480   C  CA  . MET A 1 92  ? -33.718 -15.921 30.646  1.00 26.33  ? 71  MET A CA  1 
ATOM   481   C  C   . MET A 1 92  ? -34.009 -15.513 29.203  1.00 23.54  ? 71  MET A C   1 
ATOM   482   O  O   . MET A 1 92  ? -34.628 -16.267 28.453  1.00 24.92  ? 71  MET A O   1 
ATOM   483   C  CB  . MET A 1 92  ? -32.530 -16.930 30.652  1.00 22.92  ? 71  MET A CB  1 
ATOM   484   C  CG  . MET A 1 92  ? -31.995 -17.303 32.036  1.00 24.55  ? 71  MET A CG  1 
ATOM   485   S  SD  . MET A 1 92  ? -31.232 -15.870 32.830  1.00 28.04  ? 71  MET A SD  1 
ATOM   486   C  CE  . MET A 1 92  ? -32.108 -15.906 34.370  1.00 29.46  ? 71  MET A CE  1 
ATOM   487   N  N   . GLN A 1 93  ? -33.525 -14.334 28.813  1.00 16.84  ? 72  GLN A N   1 
ATOM   488   C  CA  . GLN A 1 93  ? -33.594 -13.849 27.449  1.00 22.00  ? 72  GLN A CA  1 
ATOM   489   C  C   . GLN A 1 93  ? -32.178 -13.527 26.993  1.00 24.98  ? 72  GLN A C   1 
ATOM   490   O  O   . GLN A 1 93  ? -31.277 -13.360 27.812  1.00 26.11  ? 72  GLN A O   1 
ATOM   491   C  CB  . GLN A 1 93  ? -34.479 -12.579 27.340  1.00 21.66  ? 72  GLN A CB  1 
ATOM   492   C  CG  . GLN A 1 93  ? -33.796 -11.339 27.850  1.00 25.53  ? 72  GLN A CG  1 
ATOM   493   C  CD  . GLN A 1 93  ? -34.640 -10.048 27.702  1.00 43.49  ? 72  GLN A CD  1 
ATOM   494   O  OE1 . GLN A 1 93  ? -35.760 -9.956  28.206  1.00 29.16  ? 72  GLN A OE1 1 
ATOM   495   N  NE2 . GLN A 1 93  ? -34.064 -9.037  27.038  1.00 32.56  ? 72  GLN A NE2 1 
ATOM   496   N  N   . ARG A 1 94  ? -31.971 -13.450 25.682  1.00 20.71  ? 73  ARG A N   1 
ATOM   497   C  CA  . ARG A 1 94  ? -30.661 -13.045 25.181  1.00 20.96  ? 73  ARG A CA  1 
ATOM   498   C  C   . ARG A 1 94  ? -30.611 -11.639 24.614  1.00 21.22  ? 73  ARG A C   1 
ATOM   499   O  O   . ARG A 1 94  ? -29.510 -11.088 24.478  1.00 24.94  ? 73  ARG A O   1 
ATOM   500   C  CB  . ARG A 1 94  ? -30.178 -14.022 24.107  1.00 20.79  ? 73  ARG A CB  1 
ATOM   501   C  CG  . ARG A 1 94  ? -30.119 -15.474 24.567  1.00 18.60  ? 73  ARG A CG  1 
ATOM   502   C  CD  . ARG A 1 94  ? -29.300 -15.642 25.888  1.00 19.99  ? 73  ARG A CD  1 
ATOM   503   N  NE  . ARG A 1 94  ? -29.156 -17.068 26.181  1.00 21.14  ? 73  ARG A NE  1 
ATOM   504   C  CZ  . ARG A 1 94  ? -28.224 -17.844 25.631  1.00 22.04  ? 73  ARG A CZ  1 
ATOM   505   N  NH1 . ARG A 1 94  ? -27.304 -17.352 24.814  1.00 20.62  ? 73  ARG A NH1 1 
ATOM   506   N  NH2 . ARG A 1 94  ? -28.218 -19.147 25.908  1.00 20.47  ? 73  ARG A NH2 1 
ATOM   507   N  N   . GLU A 1 95  ? -31.749 -11.044 24.256  1.00 19.65  ? 74  GLU A N   1 
ATOM   508   C  CA  . GLU A 1 95  ? -31.681 -9.712  23.672  1.00 23.05  ? 74  GLU A CA  1 
ATOM   509   C  C   . GLU A 1 95  ? -31.016 -8.755  24.654  1.00 21.61  ? 74  GLU A C   1 
ATOM   510   O  O   . GLU A 1 95  ? -31.455 -8.631  25.802  1.00 27.32  ? 74  GLU A O   1 
ATOM   511   C  CB  . GLU A 1 95  ? -33.083 -9.195  23.300  1.00 25.13  ? 74  GLU A CB  1 
ATOM   512   C  CG  . GLU A 1 95  ? -32.944 -7.836  22.618  1.00 31.02  ? 74  GLU A CG  1 
ATOM   513   C  CD  . GLU A 1 95  ? -34.274 -7.165  22.236  1.00 46.20  ? 74  GLU A CD  1 
ATOM   514   O  OE1 . GLU A 1 95  ? -35.359 -7.748  22.444  1.00 45.92  ? 74  GLU A OE1 1 
ATOM   515   O  OE2 . GLU A 1 95  ? -34.216 -6.034  21.713  1.00 56.61  ? 74  GLU A OE2 1 
ATOM   516   N  N   . GLY A 1 96  ? -29.962 -8.080  24.201  1.00 24.54  ? 75  GLY A N   1 
ATOM   517   C  CA  . GLY A 1 96  ? -29.259 -7.114  25.024  1.00 28.21  ? 75  GLY A CA  1 
ATOM   518   C  C   . GLY A 1 96  ? -28.239 -7.706  25.981  1.00 28.68  ? 75  GLY A C   1 
ATOM   519   O  O   . GLY A 1 96  ? -27.554 -6.942  26.689  1.00 26.19  ? 75  GLY A O   1 
ATOM   520   N  N   . ALA A 1 97  ? -28.104 -9.037  26.032  1.00 24.12  ? 76  ALA A N   1 
ATOM   521   C  CA  . ALA A 1 97  ? -27.202 -9.630  27.023  1.00 22.08  ? 76  ALA A CA  1 
ATOM   522   C  C   . ALA A 1 97  ? -25.738 -9.432  26.642  1.00 19.79  ? 76  ALA A C   1 
ATOM   523   O  O   . ALA A 1 97  ? -24.913 -9.111  27.502  1.00 24.28  ? 76  ALA A O   1 
ATOM   524   C  CB  . ALA A 1 97  ? -27.515 -11.105 27.215  1.00 19.70  ? 76  ALA A CB  1 
ATOM   525   N  N   . MET A 1 98  ? -25.396 -9.625  25.387  1.00 24.57  ? 77  MET A N   1 
ATOM   526   C  CA  . MET A 1 98  ? -24.016 -9.471  24.977  1.00 21.38  ? 77  MET A CA  1 
ATOM   527   C  C   . MET A 1 98  ? -23.755 -7.998  24.705  1.00 30.29  ? 77  MET A C   1 
ATOM   528   O  O   . MET A 1 98  ? -24.531 -7.365  23.983  1.00 25.05  ? 77  MET A O   1 
ATOM   529   C  CB  . MET A 1 98  ? -23.727 -10.273 23.709  1.00 26.39  ? 77  MET A CB  1 
ATOM   530   C  CG  . MET A 1 98  ? -22.287 -10.103 23.186  1.00 22.10  ? 77  MET A CG  1 
ATOM   531   S  SD  . MET A 1 98  ? -21.167 -11.065 24.224  1.00 28.06  ? 77  MET A SD  1 
ATOM   532   C  CE  . MET A 1 98  ? -21.626 -12.768 23.734  1.00 21.45  ? 77  MET A CE  1 
ATOM   533   N  N   . PRO A 1 99  ? -22.695 -7.421  25.257  1.00 29.82  ? 78  PRO A N   1 
ATOM   534   C  CA  . PRO A 1 99  ? -22.363 -6.033  24.938  1.00 32.38  ? 78  PRO A CA  1 
ATOM   535   C  C   . PRO A 1 99  ? -22.092 -5.880  23.455  1.00 27.59  ? 78  PRO A C   1 
ATOM   536   O  O   . PRO A 1 99  ? -21.348 -6.681  22.859  1.00 26.50  ? 78  PRO A O   1 
ATOM   537   C  CB  . PRO A 1 99  ? -21.095 -5.757  25.764  1.00 34.95  ? 78  PRO A CB  1 
ATOM   538   C  CG  . PRO A 1 99  ? -21.070 -6.831  26.811  1.00 38.21  ? 78  PRO A CG  1 
ATOM   539   C  CD  . PRO A 1 99  ? -21.796 -8.019  26.261  1.00 28.54  ? 78  PRO A CD  1 
ATOM   540   N  N   . PRO A 1 100 ? -22.669 -4.846  22.831  1.00 26.18  ? 79  PRO A N   1 
ATOM   541   C  CA  . PRO A 1 100 ? -22.514 -4.669  21.384  1.00 24.53  ? 79  PRO A CA  1 
ATOM   542   C  C   . PRO A 1 100 ? -21.083 -4.594  20.916  1.00 25.30  ? 79  PRO A C   1 
ATOM   543   O  O   . PRO A 1 100 ? -20.775 -5.053  19.807  1.00 27.41  ? 79  PRO A O   1 
ATOM   544   C  CB  . PRO A 1 100 ? -23.264 -3.343  21.127  1.00 30.52  ? 79  PRO A CB  1 
ATOM   545   C  CG  . PRO A 1 100 ? -24.318 -3.321  22.187  1.00 34.41  ? 79  PRO A CG  1 
ATOM   546   C  CD  . PRO A 1 100 ? -23.646 -3.894  23.402  1.00 31.16  ? 79  PRO A CD  1 
ATOM   547   N  N   . VAL A 1 101 ? -20.185 -4.014  21.712  1.00 25.82  ? 80  VAL A N   1 
ATOM   548   C  CA  . VAL A 1 101 ? -18.800 -3.900  21.262  1.00 27.31  ? 80  VAL A CA  1 
ATOM   549   C  C   . VAL A 1 101 ? -18.186 -5.273  20.975  1.00 25.38  ? 80  VAL A C   1 
ATOM   550   O  O   . VAL A 1 101 ? -17.299 -5.393  20.131  1.00 24.34  ? 80  VAL A O   1 
ATOM   551   C  CB  . VAL A 1 101 ? -17.969 -3.110  22.288  1.00 34.40  ? 80  VAL A CB  1 
ATOM   552   C  CG1 . VAL A 1 101 ? -17.882 -3.855  23.614  1.00 29.14  ? 80  VAL A CG1 1 
ATOM   553   C  CG2 . VAL A 1 101 ? -16.578 -2.787  21.702  1.00 33.40  ? 80  VAL A CG2 1 
ATOM   554   N  N   . ILE A 1 102 ? -18.662 -6.325  21.638  1.00 24.87  ? 81  ILE A N   1 
ATOM   555   C  CA  . ILE A 1 102 ? -18.289 -7.699  21.281  1.00 22.88  ? 81  ILE A CA  1 
ATOM   556   C  C   . ILE A 1 102 ? -19.234 -8.271  20.235  1.00 24.65  ? 81  ILE A C   1 
ATOM   557   O  O   . ILE A 1 102 ? -18.791 -8.740  19.182  1.00 23.35  ? 81  ILE A O   1 
ATOM   558   C  CB  . ILE A 1 102 ? -18.257 -8.600  22.541  1.00 24.63  ? 81  ILE A CB  1 
ATOM   559   C  CG1 . ILE A 1 102 ? -17.124 -8.177  23.472  1.00 31.74  ? 81  ILE A CG1 1 
ATOM   560   C  CG2 . ILE A 1 102 ? -18.068 -10.082 22.172  1.00 27.05  ? 81  ILE A CG2 1 
ATOM   561   C  CD1 . ILE A 1 102 ? -17.247 -8.791  24.834  1.00 38.59  ? 81  ILE A CD1 1 
ATOM   562   N  N   . GLY A 1 103 ? -20.541 -8.215  20.503  1.00 24.38  ? 82  GLY A N   1 
ATOM   563   C  CA  . GLY A 1 103 ? -21.489 -8.945  19.675  1.00 24.22  ? 82  GLY A CA  1 
ATOM   564   C  C   . GLY A 1 103 ? -21.617 -8.397  18.266  1.00 26.19  ? 82  GLY A C   1 
ATOM   565   O  O   . GLY A 1 103 ? -21.687 -9.161  17.295  1.00 25.04  ? 82  GLY A O   1 
ATOM   566   N  N   . ASP A 1 104 ? -21.682 -7.070  18.133  1.00 21.90  ? 83  ASP A N   1 
ATOM   567   C  CA  . ASP A 1 104 ? -21.843 -6.486  16.814  1.00 24.51  ? 83  ASP A CA  1 
ATOM   568   C  C   . ASP A 1 104 ? -20.646 -6.783  15.933  1.00 25.05  ? 83  ASP A C   1 
ATOM   569   O  O   . ASP A 1 104 ? -20.799 -6.900  14.717  1.00 26.73  ? 83  ASP A O   1 
ATOM   570   C  CB  . ASP A 1 104 ? -22.063 -4.971  16.909  1.00 25.20  ? 83  ASP A CB  1 
ATOM   571   C  CG  . ASP A 1 104 ? -23.426 -4.625  17.378  1.00 36.01  ? 83  ASP A CG  1 
ATOM   572   O  OD1 . ASP A 1 104 ? -24.247 -5.555  17.628  1.00 30.35  ? 83  ASP A OD1 1 
ATOM   573   O  OD2 . ASP A 1 104 ? -23.674 -3.412  17.506  1.00 31.64  ? 83  ASP A OD2 1 
ATOM   574   N  N   . ALA A 1 105 ? -19.445 -6.921  16.520  1.00 22.04  ? 84  ALA A N   1 
ATOM   575   C  CA  . ALA A 1 105 ? -18.273 -7.321  15.743  1.00 23.63  ? 84  ALA A CA  1 
ATOM   576   C  C   . ALA A 1 105 ? -18.258 -8.822  15.494  1.00 25.14  ? 84  ALA A C   1 
ATOM   577   O  O   . ALA A 1 105 ? -18.086 -9.268  14.352  1.00 22.70  ? 84  ALA A O   1 
ATOM   578   C  CB  . ALA A 1 105 ? -16.989 -6.898  16.463  1.00 26.12  ? 84  ALA A CB  1 
ATOM   579   N  N   . LEU A 1 106 ? -18.465 -9.621  16.552  1.00 23.26  ? 85  LEU A N   1 
ATOM   580   C  CA  . LEU A 1 106 ? -18.293 -11.070 16.425  1.00 23.25  ? 85  LEU A CA  1 
ATOM   581   C  C   . LEU A 1 106 ? -19.390 -11.699 15.571  1.00 22.59  ? 85  LEU A C   1 
ATOM   582   O  O   . LEU A 1 106 ? -19.105 -12.465 14.634  1.00 23.33  ? 85  LEU A O   1 
ATOM   583   C  CB  . LEU A 1 106 ? -18.258 -11.713 17.813  1.00 22.27  ? 85  LEU A CB  1 
ATOM   584   C  CG  . LEU A 1 106 ? -18.049 -13.234 17.861  1.00 23.68  ? 85  LEU A CG  1 
ATOM   585   C  CD1 . LEU A 1 106 ? -16.848 -13.622 17.014  1.00 24.62  ? 85  LEU A CD1 1 
ATOM   586   C  CD2 . LEU A 1 106 ? -17.946 -13.710 19.297  1.00 25.34  ? 85  LEU A CD2 1 
ATOM   587   N  N   . VAL A 1 107 ? -20.650 -11.423 15.883  1.00 20.49  ? 86  VAL A N   1 
ATOM   588   C  CA  . VAL A 1 107 ? -21.737 -12.117 15.197  1.00 21.96  ? 86  VAL A CA  1 
ATOM   589   C  C   . VAL A 1 107 ? -22.581 -11.192 14.326  1.00 25.17  ? 86  VAL A C   1 
ATOM   590   O  O   . VAL A 1 107 ? -23.360 -11.696 13.498  1.00 24.75  ? 86  VAL A O   1 
ATOM   591   C  CB  . VAL A 1 107 ? -22.643 -12.895 16.178  1.00 23.64  ? 86  VAL A CB  1 
ATOM   592   C  CG1 . VAL A 1 107 ? -21.831 -13.876 17.040  1.00 24.25  ? 86  VAL A CG1 1 
ATOM   593   C  CG2 . VAL A 1 107 ? -23.490 -11.952 17.056  1.00 22.04  ? 86  VAL A CG2 1 
ATOM   594   N  N   . GLY A 1 108 ? -22.446 -9.877  14.461  1.00 24.15  ? 87  GLY A N   1 
ATOM   595   C  CA  . GLY A 1 108 ? -23.173 -8.939  13.623  1.00 24.06  ? 87  GLY A CA  1 
ATOM   596   C  C   . GLY A 1 108 ? -24.536 -8.556  14.187  1.00 24.78  ? 87  GLY A C   1 
ATOM   597   O  O   . GLY A 1 108 ? -25.127 -9.241  15.018  1.00 24.20  ? 87  GLY A O   1 
ATOM   598   N  N   . LYS A 1 109 ? -25.045 -7.418  13.715  1.00 23.89  ? 88  LYS A N   1 
ATOM   599   C  CA  . LYS A 1 109 ? -26.335 -6.927  14.174  1.00 24.98  ? 88  LYS A CA  1 
ATOM   600   C  C   . LYS A 1 109 ? -27.482 -7.780  13.636  1.00 25.19  ? 88  LYS A C   1 
ATOM   601   O  O   . LYS A 1 109 ? -27.454 -8.246  12.499  1.00 24.97  ? 88  LYS A O   1 
ATOM   602   C  CB  . LYS A 1 109 ? -26.518 -5.469  13.726  1.00 28.59  ? 88  LYS A CB  1 
ATOM   603   C  CG  . LYS A 1 109 ? -25.456 -4.531  14.267  1.00 31.27  ? 88  LYS A CG  1 
ATOM   604   C  CD  . LYS A 1 109 ? -25.616 -3.099  13.669  1.00 33.13  ? 88  LYS A CD  1 
ATOM   605   C  CE  . LYS A 1 109 ? -24.498 -2.162  14.174  1.00 39.26  ? 88  LYS A CE  1 
ATOM   606   N  NZ  . LYS A 1 109 ? -24.600 -0.793  13.607  1.00 61.98  ? 88  LYS A NZ  1 
ATOM   607   N  N   . GLY A 1 110 ? -28.496 -7.985  14.460  1.00 23.18  ? 89  GLY A N   1 
ATOM   608   C  CA  . GLY A 1 110 ? -29.655 -8.747  14.051  1.00 28.63  ? 89  GLY A CA  1 
ATOM   609   C  C   . GLY A 1 110 ? -29.448 -10.244 13.988  1.00 28.94  ? 89  GLY A C   1 
ATOM   610   O  O   . GLY A 1 110 ? -30.324 -10.946 13.484  1.00 26.76  ? 89  GLY A O   1 
ATOM   611   N  N   . ALA A 1 111 ? -28.314 -10.752 14.469  1.00 22.64  ? 90  ALA A N   1 
ATOM   612   C  CA  . ALA A 1 111 ? -28.033 -12.179 14.397  1.00 25.98  ? 90  ALA A CA  1 
ATOM   613   C  C   . ALA A 1 111 ? -28.970 -12.975 15.308  1.00 23.80  ? 90  ALA A C   1 
ATOM   614   O  O   . ALA A 1 111 ? -29.480 -12.471 16.324  1.00 24.15  ? 90  ALA A O   1 
ATOM   615   C  CB  . ALA A 1 111 ? -26.576 -12.452 14.792  1.00 24.97  ? 90  ALA A CB  1 
ATOM   616   N  N   . VAL A 1 112 ? -29.140 -14.262 14.960  1.00 22.21  ? 91  VAL A N   1 
ATOM   617   C  CA  . VAL A 1 112 ? -29.945 -15.209 15.739  1.00 17.96  ? 91  VAL A CA  1 
ATOM   618   C  C   . VAL A 1 112 ? -29.564 -15.197 17.213  1.00 18.80  ? 91  VAL A C   1 
ATOM   619   O  O   . VAL A 1 112 ? -30.417 -15.433 18.079  1.00 20.83  ? 91  VAL A O   1 
ATOM   620   C  CB  . VAL A 1 112 ? -29.799 -16.644 15.159  1.00 22.97  ? 91  VAL A CB  1 
ATOM   621   C  CG1 . VAL A 1 112 ? -28.310 -17.177 15.255  1.00 24.12  ? 91  VAL A CG1 1 
ATOM   622   C  CG2 . VAL A 1 112 ? -30.744 -17.631 15.892  1.00 20.69  ? 91  VAL A CG2 1 
ATOM   623   N  N   . HIS A 1 113 ? -28.285 -14.907 17.528  1.00 18.37  ? 92  HIS A N   1 
ATOM   624   C  CA  . HIS A 1 113 ? -27.839 -14.926 18.937  1.00 21.04  ? 92  HIS A CA  1 
ATOM   625   C  C   . HIS A 1 113 ? -28.635 -13.941 19.799  1.00 26.58  ? 92  HIS A C   1 
ATOM   626   O  O   . HIS A 1 113 ? -28.813 -14.155 21.006  1.00 22.35  ? 92  HIS A O   1 
ATOM   627   C  CB  . HIS A 1 113 ? -26.337 -14.577 19.012  1.00 19.50  ? 92  HIS A CB  1 
ATOM   628   C  CG  . HIS A 1 113 ? -25.461 -15.401 18.108  1.00 18.88  ? 92  HIS A CG  1 
ATOM   629   N  ND1 . HIS A 1 113 ? -25.524 -15.324 16.733  1.00 19.42  ? 92  HIS A ND1 1 
ATOM   630   C  CD2 . HIS A 1 113 ? -24.459 -16.276 18.388  1.00 18.21  ? 92  HIS A CD2 1 
ATOM   631   C  CE1 . HIS A 1 113 ? -24.638 -16.161 16.206  1.00 21.86  ? 92  HIS A CE1 1 
ATOM   632   N  NE2 . HIS A 1 113 ? -23.958 -16.722 17.186  1.00 20.98  ? 92  HIS A NE2 1 
ATOM   633   N  N   . ASN A 1 114 ? -29.123 -12.863 19.194  1.00 22.05  ? 93  ASN A N   1 
ATOM   634   C  CA  . ASN A 1 114 ? -29.825 -11.788 19.888  1.00 24.66  ? 93  ASN A CA  1 
ATOM   635   C  C   . ASN A 1 114 ? -31.325 -12.002 19.978  1.00 29.76  ? 93  ASN A C   1 
ATOM   636   O  O   . ASN A 1 114 ? -32.004 -11.194 20.616  1.00 26.80  ? 93  ASN A O   1 
ATOM   637   C  CB  . ASN A 1 114 ? -29.583 -10.448 19.171  1.00 28.64  ? 93  ASN A CB  1 
ATOM   638   C  CG  . ASN A 1 114 ? -28.116 -10.099 19.089  1.00 51.28  ? 93  ASN A CG  1 
ATOM   639   O  OD1 . ASN A 1 114 ? -27.378 -10.265 20.067  1.00 49.26  ? 93  ASN A OD1 1 
ATOM   640   N  ND2 . ASN A 1 114 ? -27.672 -9.637  17.915  1.00 43.66  ? 93  ASN A ND2 1 
ATOM   641   N  N   . LEU A 1 115 ? -31.861 -13.048 19.356  1.00 20.41  ? 94  LEU A N   1 
ATOM   642   C  CA  . LEU A 1 115 ? -33.307 -13.227 19.249  1.00 20.45  ? 94  LEU A CA  1 
ATOM   643   C  C   . LEU A 1 115 ? -33.842 -14.086 20.396  1.00 22.28  ? 94  LEU A C   1 
ATOM   644   O  O   . LEU A 1 115 ? -33.131 -14.917 20.968  1.00 22.99  ? 94  LEU A O   1 
ATOM   645   C  CB  . LEU A 1 115 ? -33.654 -13.882 17.897  1.00 21.04  ? 94  LEU A CB  1 
ATOM   646   C  CG  . LEU A 1 115 ? -33.193 -13.169 16.617  1.00 26.07  ? 94  LEU A CG  1 
ATOM   647   C  CD1 . LEU A 1 115 ? -33.645 -13.965 15.328  1.00 20.76  ? 94  LEU A CD1 1 
ATOM   648   C  CD2 . LEU A 1 115 ? -33.709 -11.721 16.549  1.00 32.43  ? 94  LEU A CD2 1 
ATOM   649   N  N   . ASP A 1 116 ? -35.121 -13.898 20.717  1.00 18.15  ? 95  ASP A N   1 
ATOM   650   C  CA  . ASP A 1 116 ? -35.793 -14.684 21.736  1.00 21.49  ? 95  ASP A CA  1 
ATOM   651   C  C   . ASP A 1 116 ? -37.117 -15.203 21.190  1.00 22.72  ? 95  ASP A C   1 
ATOM   652   O  O   . ASP A 1 116 ? -37.620 -14.730 20.166  1.00 23.20  ? 95  ASP A O   1 
ATOM   653   C  CB  . ASP A 1 116 ? -36.032 -13.849 23.007  1.00 23.02  ? 95  ASP A CB  1 
ATOM   654   C  CG  . ASP A 1 116 ? -34.718 -13.393 23.647  1.00 29.57  ? 95  ASP A CG  1 
ATOM   655   O  OD1 . ASP A 1 116 ? -33.913 -14.283 24.057  1.00 24.39  ? 95  ASP A OD1 1 
ATOM   656   O  OD2 . ASP A 1 116 ? -34.475 -12.161 23.683  1.00 24.58  ? 95  ASP A OD2 1 
ATOM   657   N  N   . GLY A 1 117 ? -37.675 -16.188 21.886  1.00 19.27  ? 96  GLY A N   1 
ATOM   658   C  CA  . GLY A 1 117 ? -39.069 -16.540 21.586  1.00 24.39  ? 96  GLY A CA  1 
ATOM   659   C  C   . GLY A 1 117 ? -39.266 -17.205 20.230  1.00 24.33  ? 96  GLY A C   1 
ATOM   660   O  O   . GLY A 1 117 ? -38.358 -17.819 19.661  1.00 21.36  ? 96  GLY A O   1 
ATOM   661   N  N   . GLU A 1 118 ? -40.478 -17.068 19.683  1.00 23.28  ? 97  GLU A N   1 
ATOM   662   C  CA  . GLU A 1 118 ? -40.769 -17.754 18.427  1.00 23.36  ? 97  GLU A CA  1 
ATOM   663   C  C   . GLU A 1 118 ? -39.875 -17.243 17.299  1.00 22.02  ? 97  GLU A C   1 
ATOM   664   O  O   . GLU A 1 118 ? -39.433 -18.027 16.457  1.00 25.39  ? 97  GLU A O   1 
ATOM   665   C  CB  . GLU A 1 118 ? -42.248 -17.604 18.057  1.00 28.09  ? 97  GLU A CB  1 
ATOM   666   C  CG  . GLU A 1 118 ? -42.665 -18.558 16.919  1.00 31.15  ? 97  GLU A CG  1 
ATOM   667   C  CD  . GLU A 1 118 ? -43.693 -17.937 15.977  1.00 53.68  ? 97  GLU A CD  1 
ATOM   668   O  OE1 . GLU A 1 118 ? -43.897 -16.698 16.057  1.00 44.83  ? 97  GLU A OE1 1 
ATOM   669   O  OE2 . GLU A 1 118 ? -44.307 -18.689 15.170  1.00 39.63  ? 97  GLU A OE2 1 
ATOM   670   N  N   . GLU A 1 119 ? -39.560 -15.948 17.278  1.00 22.41  ? 98  GLU A N   1 
ATOM   671   C  CA  . GLU A 1 119 ? -38.666 -15.478 16.215  1.00 22.49  ? 98  GLU A CA  1 
ATOM   672   C  C   . GLU A 1 119 ? -37.311 -16.180 16.304  1.00 22.56  ? 98  GLU A C   1 
ATOM   673   O  O   . GLU A 1 119 ? -36.740 -16.560 15.277  1.00 21.66  ? 98  GLU A O   1 
ATOM   674   C  CB  . GLU A 1 119 ? -38.471 -13.963 16.270  1.00 27.27  ? 98  GLU A CB  1 
ATOM   675   C  CG  . GLU A 1 119 ? -39.746 -13.187 15.966  1.00 29.78  ? 98  GLU A CG  1 
ATOM   676   C  CD  . GLU A 1 119 ? -40.144 -13.176 14.466  1.00 32.74  ? 98  GLU A CD  1 
ATOM   677   O  OE1 . GLU A 1 119 ? -39.513 -13.841 13.603  1.00 29.88  ? 98  GLU A OE1 1 
ATOM   678   O  OE2 . GLU A 1 119 ? -41.130 -12.486 14.144  1.00 39.28  ? 98  GLU A OE2 1 
ATOM   679   N  N   . HIS A 1 120 ? -36.790 -16.356 17.523  1.00 23.38  ? 99  HIS A N   1 
ATOM   680   C  CA  . HIS A 1 120 ? -35.549 -17.116 17.657  1.00 22.77  ? 99  HIS A CA  1 
ATOM   681   C  C   . HIS A 1 120 ? -35.722 -18.555 17.154  1.00 19.78  ? 99  HIS A C   1 
ATOM   682   O  O   . HIS A 1 120 ? -34.880 -19.078 16.423  1.00 20.37  ? 99  HIS A O   1 
ATOM   683   C  CB  . HIS A 1 120 ? -35.078 -17.160 19.106  1.00 19.58  ? 99  HIS A CB  1 
ATOM   684   C  CG  . HIS A 1 120 ? -33.903 -18.079 19.263  1.00 22.41  ? 99  HIS A CG  1 
ATOM   685   N  ND1 . HIS A 1 120 ? -34.014 -19.343 19.806  1.00 21.51  ? 99  HIS A ND1 1 
ATOM   686   C  CD2 . HIS A 1 120 ? -32.622 -17.971 18.826  1.00 20.84  ? 99  HIS A CD2 1 
ATOM   687   C  CE1 . HIS A 1 120 ? -32.841 -19.956 19.746  1.00 17.74  ? 99  HIS A CE1 1 
ATOM   688   N  NE2 . HIS A 1 120 ? -31.975 -19.139 19.177  1.00 22.10  ? 99  HIS A NE2 1 
ATOM   689   N  N   . LYS A 1 121 ? -36.800 -19.215 17.561  1.00 20.97  ? 100 LYS A N   1 
ATOM   690   C  CA  . LYS A 1 121 ? -37.005 -20.603 17.150  1.00 23.34  ? 100 LYS A CA  1 
ATOM   691   C  C   . LYS A 1 121 ? -37.062 -20.756 15.625  1.00 20.82  ? 100 LYS A C   1 
ATOM   692   O  O   . LYS A 1 121 ? -36.492 -21.702 15.074  1.00 22.99  ? 100 LYS A O   1 
ATOM   693   C  CB  . LYS A 1 121 ? -38.278 -21.136 17.811  1.00 30.15  ? 100 LYS A CB  1 
ATOM   694   C  CG  . LYS A 1 121 ? -38.514 -22.632 17.612  1.00 40.72  ? 100 LYS A CG  1 
ATOM   695   C  CD  . LYS A 1 121 ? -39.797 -23.086 18.323  1.00 70.30  ? 100 LYS A CD  1 
ATOM   696   C  CE  . LYS A 1 121 ? -41.052 -22.329 17.836  1.00 69.30  ? 100 LYS A CE  1 
ATOM   697   N  NZ  . LYS A 1 121 ? -41.493 -22.685 16.445  1.00 79.35  ? 100 LYS A NZ  1 
ATOM   698   N  N   . VAL A 1 122 ? -37.738 -19.830 14.934  1.00 22.15  ? 101 VAL A N   1 
ATOM   699   C  CA  . VAL A 1 122 ? -37.876 -19.887 13.477  1.00 23.16  ? 101 VAL A CA  1 
ATOM   700   C  C   . VAL A 1 122 ? -36.525 -19.671 12.782  1.00 20.93  ? 101 VAL A C   1 
ATOM   701   O  O   . VAL A 1 122 ? -36.179 -20.366 11.811  1.00 23.13  ? 101 VAL A O   1 
ATOM   702   C  CB  . VAL A 1 122 ? -38.927 -18.852 13.023  1.00 22.37  ? 101 VAL A CB  1 
ATOM   703   C  CG1 . VAL A 1 122 ? -38.910 -18.622 11.478  1.00 21.68  ? 101 VAL A CG1 1 
ATOM   704   C  CG2 . VAL A 1 122 ? -40.340 -19.300 13.527  1.00 23.81  ? 101 VAL A CG2 1 
ATOM   705   N  N   . ARG A 1 123 ? -35.775 -18.663 13.222  1.00 20.53  ? 102 ARG A N   1 
ATOM   706   C  CA  . ARG A 1 123 ? -34.455 -18.400 12.661  1.00 19.61  ? 102 ARG A CA  1 
ATOM   707   C  C   . ARG A 1 123 ? -33.510 -19.572 12.943  1.00 19.53  ? 102 ARG A C   1 
ATOM   708   O  O   . ARG A 1 123 ? -32.768 -20.040 12.054  1.00 21.39  ? 102 ARG A O   1 
ATOM   709   C  CB  . ARG A 1 123 ? -33.928 -17.091 13.275  1.00 19.70  ? 102 ARG A CB  1 
ATOM   710   C  CG  . ARG A 1 123 ? -32.487 -16.670 12.862  1.00 21.96  ? 102 ARG A CG  1 
ATOM   711   C  CD  . ARG A 1 123 ? -32.432 -16.027 11.435  1.00 24.68  ? 102 ARG A CD  1 
ATOM   712   N  NE  . ARG A 1 123 ? -33.214 -14.799 11.404  1.00 23.08  ? 102 ARG A NE  1 
ATOM   713   C  CZ  . ARG A 1 123 ? -32.772 -13.612 11.799  1.00 29.54  ? 102 ARG A CZ  1 
ATOM   714   N  NH1 . ARG A 1 123 ? -31.498 -13.411 12.105  1.00 23.81  ? 102 ARG A NH1 1 
ATOM   715   N  NH2 . ARG A 1 123 ? -33.637 -12.607 11.912  1.00 30.29  ? 102 ARG A NH2 1 
ATOM   716   N  N   . LYS A 1 124 ? -33.526 -20.063 14.180  1.00 18.70  ? 103 LYS A N   1 
ATOM   717   C  CA  . LYS A 1 124 ? -32.624 -21.152 14.563  1.00 20.44  ? 103 LYS A CA  1 
ATOM   718   C  C   . LYS A 1 124 ? -32.970 -22.449 13.820  1.00 23.89  ? 103 LYS A C   1 
ATOM   719   O  O   . LYS A 1 124 ? -32.069 -23.193 13.409  1.00 21.58  ? 103 LYS A O   1 
ATOM   720   C  CB  . LYS A 1 124 ? -32.684 -21.349 16.084  1.00 17.67  ? 103 LYS A CB  1 
ATOM   721   C  CG  . LYS A 1 124 ? -31.831 -22.544 16.651  1.00 17.14  ? 103 LYS A CG  1 
ATOM   722   C  CD  . LYS A 1 124 ? -30.359 -22.330 16.306  1.00 21.27  ? 103 LYS A CD  1 
ATOM   723   C  CE  . LYS A 1 124 ? -29.467 -23.317 17.114  1.00 18.68  ? 103 LYS A CE  1 
ATOM   724   N  NZ  . LYS A 1 124 ? -29.469 -22.859 18.544  1.00 20.36  ? 103 LYS A NZ  1 
ATOM   725   N  N   . ALA A 1 125 ? -34.262 -22.713 13.581  1.00 20.81  ? 104 ALA A N   1 
ATOM   726   C  CA  . ALA A 1 125 ? -34.601 -23.897 12.795  1.00 21.75  ? 104 ALA A CA  1 
ATOM   727   C  C   . ALA A 1 125 ? -33.943 -23.849 11.427  1.00 21.03  ? 104 ALA A C   1 
ATOM   728   O  O   . ALA A 1 125 ? -33.443 -24.868 10.936  1.00 22.29  ? 104 ALA A O   1 
ATOM   729   C  CB  . ALA A 1 125 ? -36.120 -24.043 12.649  1.00 24.22  ? 104 ALA A CB  1 
ATOM   730   N  N   . GLN A 1 126 ? -33.950 -22.669 10.783  1.00 21.21  ? 105 GLN A N   1 
ATOM   731   C  CA  . GLN A 1 126 ? -33.400 -22.559 9.446   1.00 19.74  ? 105 GLN A CA  1 
ATOM   732   C  C   . GLN A 1 126 ? -31.877 -22.677 9.448   1.00 23.29  ? 105 GLN A C   1 
ATOM   733   O  O   . GLN A 1 126 ? -31.287 -23.172 8.480   1.00 23.93  ? 105 GLN A O   1 
ATOM   734   C  CB  . GLN A 1 126 ? -33.858 -21.226 8.824   1.00 20.10  ? 105 GLN A CB  1 
ATOM   735   C  CG  . GLN A 1 126 ? -35.322 -21.258 8.412   1.00 22.37  ? 105 GLN A CG  1 
ATOM   736   C  CD  . GLN A 1 126 ? -35.822 -19.872 8.062   1.00 22.22  ? 105 GLN A CD  1 
ATOM   737   O  OE1 . GLN A 1 126 ? -35.651 -19.427 6.928   1.00 26.62  ? 105 GLN A OE1 1 
ATOM   738   N  NE2 . GLN A 1 126 ? -36.387 -19.153 9.056   1.00 24.33  ? 105 GLN A NE2 1 
ATOM   739   N  N   . MET A 1 127 ? -31.223 -22.189 10.501  1.00 21.87  ? 106 MET A N   1 
ATOM   740   C  CA  . MET A 1 127 ? -29.767 -22.286 10.574  1.00 22.20  ? 106 MET A CA  1 
ATOM   741   C  C   . MET A 1 127 ? -29.318 -23.680 11.009  1.00 21.84  ? 106 MET A C   1 
ATOM   742   O  O   . MET A 1 127 ? -28.354 -24.211 10.455  1.00 24.83  ? 106 MET A O   1 
ATOM   743   C  CB  . MET A 1 127 ? -29.239 -21.168 11.490  1.00 21.09  ? 106 MET A CB  1 
ATOM   744   C  CG  . MET A 1 127 ? -29.363 -19.786 10.693  1.00 25.75  ? 106 MET A CG  1 
ATOM   745   S  SD  . MET A 1 127 ? -28.971 -18.427 11.710  1.00 34.91  ? 106 MET A SD  1 
ATOM   746   C  CE  . MET A 1 127 ? -27.155 -18.575 11.473  1.00 24.68  ? 106 MET A CE  1 
ATOM   747   N  N   . ALA A 1 128 ? -30.004 -24.293 11.976  1.00 18.36  ? 107 ALA A N   1 
ATOM   748   C  CA  . ALA A 1 128 ? -29.690 -25.665 12.371  1.00 21.84  ? 107 ALA A CA  1 
ATOM   749   C  C   . ALA A 1 128 ? -29.951 -26.650 11.228  1.00 26.75  ? 107 ALA A C   1 
ATOM   750   O  O   . ALA A 1 128 ? -29.250 -27.659 11.096  1.00 23.53  ? 107 ALA A O   1 
ATOM   751   C  CB  . ALA A 1 128 ? -30.516 -26.062 13.608  1.00 20.70  ? 107 ALA A CB  1 
ATOM   752   N  N   . ALA A 1 129 ? -30.906 -26.340 10.349  1.00 22.35  ? 108 ALA A N   1 
ATOM   753   C  CA  . ALA A 1 129 ? -31.156 -27.224 9.217   1.00 23.55  ? 108 ALA A CA  1 
ATOM   754   C  C   . ALA A 1 129 ? -29.933 -27.309 8.315   1.00 25.52  ? 108 ALA A C   1 
ATOM   755   O  O   . ALA A 1 129 ? -29.692 -28.358 7.704   1.00 24.52  ? 108 ALA A O   1 
ATOM   756   C  CB  . ALA A 1 129 ? -32.391 -26.744 8.432   1.00 25.35  ? 108 ALA A CB  1 
ATOM   757   N  N   . MET A 1 130 ? -29.127 -26.236 8.275   1.00 21.27  ? 109 MET A N   1 
ATOM   758   C  CA  . MET A 1 130 ? -27.909 -26.190 7.478   1.00 21.71  ? 109 MET A CA  1 
ATOM   759   C  C   . MET A 1 130 ? -26.735 -26.826 8.215   1.00 23.01  ? 109 MET A C   1 
ATOM   760   O  O   . MET A 1 130 ? -26.043 -27.678 7.659   1.00 23.81  ? 109 MET A O   1 
ATOM   761   C  CB  . MET A 1 130 ? -27.571 -24.741 7.114   1.00 24.85  ? 109 MET A CB  1 
ATOM   762   C  CG  . MET A 1 130 ? -28.631 -24.053 6.203   1.00 25.07  ? 109 MET A CG  1 
ATOM   763   S  SD  . MET A 1 130 ? -28.935 -24.994 4.682   1.00 26.41  ? 109 MET A SD  1 
ATOM   764   C  CE  . MET A 1 130 ? -30.540 -25.787 5.010   1.00 29.07  ? 109 MET A CE  1 
ATOM   765   N  N   . ALA A 1 131 ? -26.489 -26.427 9.455   1.00 22.12  ? 110 ALA A N   1 
ATOM   766   C  CA  . ALA A 1 131 ? -25.249 -26.837 10.129  1.00 23.52  ? 110 ALA A CA  1 
ATOM   767   C  C   . ALA A 1 131 ? -25.358 -28.172 10.841  1.00 22.46  ? 110 ALA A C   1 
ATOM   768   O  O   . ALA A 1 131 ? -24.338 -28.859 11.009  1.00 24.19  ? 110 ALA A O   1 
ATOM   769   C  CB  . ALA A 1 131 ? -24.807 -25.779 11.162  1.00 20.45  ? 110 ALA A CB  1 
ATOM   770   N  N   . TYR A 1 132 ? -26.550 -28.549 11.303  1.00 21.73  ? 111 TYR A N   1 
ATOM   771   C  CA  . TYR A 1 132 ? -26.692 -29.620 12.287  1.00 20.26  ? 111 TYR A CA  1 
ATOM   772   C  C   . TYR A 1 132 ? -27.220 -30.922 11.703  1.00 25.31  ? 111 TYR A C   1 
ATOM   773   O  O   . TYR A 1 132 ? -27.149 -31.960 12.378  1.00 30.27  ? 111 TYR A O   1 
ATOM   774   C  CB  . TYR A 1 132 ? -27.625 -29.169 13.417  1.00 20.55  ? 111 TYR A CB  1 
ATOM   775   C  CG  . TYR A 1 132 ? -27.701 -30.053 14.656  1.00 25.47  ? 111 TYR A CG  1 
ATOM   776   C  CD1 . TYR A 1 132 ? -26.637 -30.132 15.558  1.00 22.28  ? 111 TYR A CD1 1 
ATOM   777   C  CD2 . TYR A 1 132 ? -28.860 -30.757 14.964  1.00 29.03  ? 111 TYR A CD2 1 
ATOM   778   C  CE1 . TYR A 1 132 ? -26.719 -30.912 16.721  1.00 23.80  ? 111 TYR A CE1 1 
ATOM   779   C  CE2 . TYR A 1 132 ? -28.943 -31.565 16.140  1.00 30.13  ? 111 TYR A CE2 1 
ATOM   780   C  CZ  . TYR A 1 132 ? -27.880 -31.620 16.995  1.00 27.57  ? 111 TYR A CZ  1 
ATOM   781   O  OH  . TYR A 1 132 ? -27.927 -32.377 18.139  1.00 28.00  ? 111 TYR A OH  1 
ATOM   782   N  N   . GLU A 1 133 ? -27.740 -30.908 10.480  1.00 23.25  ? 112 GLU A N   1 
ATOM   783   C  CA  . GLU A 1 133 ? -28.242 -32.145 9.896   1.00 26.79  ? 112 GLU A CA  1 
ATOM   784   C  C   . GLU A 1 133 ? -27.095 -33.044 9.449   1.00 22.41  ? 112 GLU A C   1 
ATOM   785   O  O   . GLU A 1 133 ? -26.188 -32.599 8.746   1.00 22.37  ? 112 GLU A O   1 
ATOM   786   C  CB  . GLU A 1 133 ? -29.169 -31.839 8.735   1.00 27.17  ? 112 GLU A CB  1 
ATOM   787   C  CG  . GLU A 1 133 ? -30.457 -31.135 9.221   1.00 39.96  ? 112 GLU A CG  1 
ATOM   788   C  CD  . GLU A 1 133 ? -31.089 -31.775 10.486  1.00 69.85  ? 112 GLU A CD  1 
ATOM   789   O  OE1 . GLU A 1 133 ? -31.195 -33.024 10.554  1.00 60.31  ? 112 GLU A OE1 1 
ATOM   790   O  OE2 . GLU A 1 133 ? -31.489 -31.020 11.419  1.00 60.72  ? 112 GLU A OE2 1 
ATOM   791   N  N   . ASP A 1 134 ? -27.183 -34.324 9.818   1.00 23.27  ? 113 ASP A N   1 
ATOM   792   C  CA  . ASP A 1 134 ? -26.109 -35.281 9.541   1.00 25.88  ? 113 ASP A CA  1 
ATOM   793   C  C   . ASP A 1 134 ? -25.740 -35.342 8.064   1.00 24.31  ? 113 ASP A C   1 
ATOM   794   O  O   . ASP A 1 134 ? -24.560 -35.463 7.732   1.00 27.84  ? 113 ASP A O   1 
ATOM   795   C  CB  . ASP A 1 134 ? -26.507 -36.678 10.050  1.00 24.68  ? 113 ASP A CB  1 
ATOM   796   C  CG  . ASP A 1 134 ? -26.456 -36.785 11.578  1.00 38.60  ? 113 ASP A CG  1 
ATOM   797   O  OD1 . ASP A 1 134 ? -25.793 -35.945 12.250  1.00 31.26  ? 113 ASP A OD1 1 
ATOM   798   O  OD2 . ASP A 1 134 ? -27.097 -37.718 12.111  1.00 39.29  ? 113 ASP A OD2 1 
ATOM   799   N  N   . GLU A 1 135 ? -26.723 -35.274 7.149   1.00 26.69  ? 114 GLU A N   1 
ATOM   800   C  CA  . GLU A 1 135 ? -26.353 -35.348 5.729   1.00 29.24  ? 114 GLU A CA  1 
ATOM   801   C  C   . GLU A 1 135 ? -25.542 -34.138 5.287   1.00 25.77  ? 114 GLU A C   1 
ATOM   802   O  O   . GLU A 1 135 ? -24.696 -34.255 4.399   1.00 25.44  ? 114 GLU A O   1 
ATOM   803   C  CB  . GLU A 1 135 ? -27.588 -35.498 4.820   1.00 27.97  ? 114 GLU A CB  1 
ATOM   804   C  CG  . GLU A 1 135 ? -28.873 -35.024 5.431   1.00 63.92  ? 114 GLU A CG  1 
ATOM   805   C  CD  . GLU A 1 135 ? -29.420 -35.996 6.464   1.00 71.88  ? 114 GLU A CD  1 
ATOM   806   O  OE1 . GLU A 1 135 ? -29.650 -37.183 6.130   1.00 79.86  ? 114 GLU A OE1 1 
ATOM   807   O  OE2 . GLU A 1 135 ? -29.592 -35.564 7.618   1.00 35.22  ? 114 GLU A OE2 1 
ATOM   808   N  N   . ARG A 1 136 ? -25.809 -32.971 5.853   1.00 22.90  ? 115 ARG A N   1 
ATOM   809   C  CA  . ARG A 1 136 ? -25.038 -31.796 5.487   1.00 23.18  ? 115 ARG A CA  1 
ATOM   810   C  C   . ARG A 1 136 ? -23.655 -31.845 6.118   1.00 20.64  ? 115 ARG A C   1 
ATOM   811   O  O   . ARG A 1 136 ? -22.681 -31.404 5.507   1.00 23.52  ? 115 ARG A O   1 
ATOM   812   C  CB  . ARG A 1 136 ? -25.759 -30.526 5.911   1.00 27.47  ? 115 ARG A CB  1 
ATOM   813   C  CG  . ARG A 1 136 ? -27.072 -30.398 5.178   1.00 31.87  ? 115 ARG A CG  1 
ATOM   814   C  CD  . ARG A 1 136 ? -27.544 -28.992 5.100   1.00 36.67  ? 115 ARG A CD  1 
ATOM   815   N  NE  . ARG A 1 136 ? -28.760 -28.939 4.304   1.00 31.17  ? 115 ARG A NE  1 
ATOM   816   C  CZ  . ARG A 1 136 ? -28.833 -28.448 3.078   1.00 29.97  ? 115 ARG A CZ  1 
ATOM   817   N  NH1 . ARG A 1 136 ? -27.760 -28.007 2.445   1.00 31.83  ? 115 ARG A NH1 1 
ATOM   818   N  NH2 . ARG A 1 136 ? -30.019 -28.371 2.482   1.00 32.39  ? 115 ARG A NH2 1 
ATOM   819   N  N   . VAL A 1 137 ? -23.557 -32.381 7.333   1.00 21.35  ? 116 VAL A N   1 
ATOM   820   C  CA  . VAL A 1 137 ? -22.237 -32.598 7.920   1.00 21.93  ? 116 VAL A CA  1 
ATOM   821   C  C   . VAL A 1 137 ? -21.427 -33.555 7.056   1.00 24.56  ? 116 VAL A C   1 
ATOM   822   O  O   . VAL A 1 137 ? -20.219 -33.358 6.841   1.00 21.86  ? 116 VAL A O   1 
ATOM   823   C  CB  . VAL A 1 137 ? -22.387 -33.123 9.355   1.00 21.41  ? 116 VAL A CB  1 
ATOM   824   C  CG1 . VAL A 1 137 ? -21.001 -33.487 9.954   1.00 21.82  ? 116 VAL A CG1 1 
ATOM   825   C  CG2 . VAL A 1 137 ? -23.075 -32.034 10.206  1.00 21.62  ? 116 VAL A CG2 1 
ATOM   826   N  N   . ALA A 1 138 ? -22.069 -34.632 6.588   1.00 24.11  ? 117 ALA A N   1 
ATOM   827   C  CA  . ALA A 1 138 ? -21.402 -35.597 5.717   1.00 24.37  ? 117 ALA A CA  1 
ATOM   828   C  C   . ALA A 1 138 ? -20.882 -34.952 4.438   1.00 23.92  ? 117 ALA A C   1 
ATOM   829   O  O   . ALA A 1 138 ? -19.887 -35.423 3.875   1.00 24.89  ? 117 ALA A O   1 
ATOM   830   C  CB  . ALA A 1 138 ? -22.364 -36.749 5.402   1.00 25.53  ? 117 ALA A CB  1 
ATOM   831   N  N   . GLU A 1 139 ? -21.547 -33.892 3.946   1.00 25.13  ? 118 GLU A N   1 
ATOM   832   C  CA  . GLU A 1 139 ? -21.032 -33.149 2.797   1.00 23.01  ? 118 GLU A CA  1 
ATOM   833   C  C   . GLU A 1 139 ? -19.795 -32.347 3.175   1.00 26.06  ? 118 GLU A C   1 
ATOM   834   O  O   . GLU A 1 139 ? -18.890 -32.189 2.368   1.00 24.28  ? 118 GLU A O   1 
ATOM   835   C  CB  . GLU A 1 139 ? -22.076 -32.175 2.247   1.00 25.72  ? 118 GLU A CB  1 
ATOM   836   C  CG  . GLU A 1 139 ? -23.269 -32.861 1.528   1.00 30.37  ? 118 GLU A CG  1 
ATOM   837   C  CD  . GLU A 1 139 ? -24.407 -31.891 1.201   1.00 44.50  ? 118 GLU A CD  1 
ATOM   838   O  OE1 . GLU A 1 139 ? -24.173 -30.654 1.150   1.00 43.01  ? 118 GLU A OE1 1 
ATOM   839   O  OE2 . GLU A 1 139 ? -25.547 -32.375 1.002   1.00 56.33  ? 118 GLU A OE2 1 
ATOM   840   N  N   . PHE A 1 140 ? -19.742 -31.840 4.404   1.00 21.60  ? 119 PHE A N   1 
ATOM   841   C  CA  . PHE A 1 140 ? -18.587 -31.046 4.825   1.00 20.78  ? 119 PHE A CA  1 
ATOM   842   C  C   . PHE A 1 140 ? -17.322 -31.906 4.994   1.00 20.38  ? 119 PHE A C   1 
ATOM   843   O  O   . PHE A 1 140 ? -16.215 -31.466 4.666   1.00 23.67  ? 119 PHE A O   1 
ATOM   844   C  CB  . PHE A 1 140 ? -18.945 -30.336 6.137   1.00 20.79  ? 119 PHE A CB  1 
ATOM   845   C  CG  . PHE A 1 140 ? -17.824 -29.516 6.689   1.00 19.88  ? 119 PHE A CG  1 
ATOM   846   C  CD1 . PHE A 1 140 ? -17.445 -28.324 6.062   1.00 21.32  ? 119 PHE A CD1 1 
ATOM   847   C  CD2 . PHE A 1 140 ? -17.136 -29.938 7.823   1.00 20.78  ? 119 PHE A CD2 1 
ATOM   848   C  CE1 . PHE A 1 140 ? -16.411 -27.551 6.579   1.00 21.83  ? 119 PHE A CE1 1 
ATOM   849   C  CE2 . PHE A 1 140 ? -16.094 -29.165 8.354   1.00 18.35  ? 119 PHE A CE2 1 
ATOM   850   C  CZ  . PHE A 1 140 ? -15.734 -27.964 7.726   1.00 19.41  ? 119 PHE A CZ  1 
ATOM   851   N  N   . ALA A 1 141 ? -17.475 -33.135 5.492   1.00 21.08  ? 120 ALA A N   1 
ATOM   852   C  CA  . ALA A 1 141 ? -16.318 -33.944 5.888   1.00 23.73  ? 120 ALA A CA  1 
ATOM   853   C  C   . ALA A 1 141 ? -15.288 -34.153 4.778   1.00 22.81  ? 120 ALA A C   1 
ATOM   854   O  O   . ALA A 1 141 ? -14.080 -33.965 5.042   1.00 23.01  ? 120 ALA A O   1 
ATOM   855   C  CB  . ALA A 1 141 ? -16.823 -35.284 6.453   1.00 20.56  ? 120 ALA A CB  1 
ATOM   856   N  N   . PRO A 1 142 ? -15.647 -34.556 3.554   1.00 21.59  ? 121 PRO A N   1 
ATOM   857   C  CA  . PRO A 1 142 ? -14.589 -34.709 2.528   1.00 21.39  ? 121 PRO A CA  1 
ATOM   858   C  C   . PRO A 1 142 ? -13.989 -33.393 2.092   1.00 23.48  ? 121 PRO A C   1 
ATOM   859   O  O   . PRO A 1 142 ? -12.825 -33.372 1.671   1.00 24.19  ? 121 PRO A O   1 
ATOM   860   C  CB  . PRO A 1 142 ? -15.315 -35.391 1.358   1.00 27.17  ? 121 PRO A CB  1 
ATOM   861   C  CG  . PRO A 1 142 ? -16.735 -35.054 1.558   1.00 25.92  ? 121 PRO A CG  1 
ATOM   862   C  CD  . PRO A 1 142 ? -16.947 -35.036 3.046   1.00 25.96  ? 121 PRO A CD  1 
ATOM   863   N  N   . LEU A 1 143 ? -14.751 -32.290 2.188   1.00 20.68  ? 122 LEU A N   1 
ATOM   864   C  CA  . LEU A 1 143 ? -14.209 -30.991 1.793   1.00 22.28  ? 122 LEU A CA  1 
ATOM   865   C  C   . LEU A 1 143 ? -13.145 -30.535 2.780   1.00 24.15  ? 122 LEU A C   1 
ATOM   866   O  O   . LEU A 1 143 ? -12.094 -29.999 2.382   1.00 21.03  ? 122 LEU A O   1 
ATOM   867   C  CB  . LEU A 1 143 ? -15.333 -29.945 1.729   1.00 21.19  ? 122 LEU A CB  1 
ATOM   868   C  CG  . LEU A 1 143 ? -16.357 -30.219 0.609   1.00 25.72  ? 122 LEU A CG  1 
ATOM   869   C  CD1 . LEU A 1 143 ? -17.588 -29.328 0.794   1.00 22.28  ? 122 LEU A CD1 1 
ATOM   870   C  CD2 . LEU A 1 143 ? -15.705 -29.892 -0.724  1.00 26.80  ? 122 LEU A CD2 1 
ATOM   871   N  N   . VAL A 1 144 ? -13.420 -30.699 4.074   1.00 22.30  ? 123 VAL A N   1 
ATOM   872   C  CA  . VAL A 1 144 ? -12.447 -30.223 5.059   1.00 23.06  ? 123 VAL A CA  1 
ATOM   873   C  C   . VAL A 1 144 ? -11.228 -31.143 5.077   1.00 23.59  ? 123 VAL A C   1 
ATOM   874   O  O   . VAL A 1 144 ? -10.103 -30.670 5.273   1.00 22.80  ? 123 VAL A O   1 
ATOM   875   C  CB  . VAL A 1 144 ? -13.096 -30.053 6.450   1.00 24.97  ? 123 VAL A CB  1 
ATOM   876   C  CG1 . VAL A 1 144 ? -13.370 -31.389 7.123   1.00 21.76  ? 123 VAL A CG1 1 
ATOM   877   C  CG2 . VAL A 1 144 ? -12.202 -29.157 7.369   1.00 21.05  ? 123 VAL A CG2 1 
ATOM   878   N  N   . ALA A 1 145 ? -11.404 -32.457 4.841   1.00 22.55  ? 124 ALA A N   1 
ATOM   879   C  CA  . ALA A 1 145 ? -10.238 -33.338 4.720   1.00 22.06  ? 124 ALA A CA  1 
ATOM   880   C  C   . ALA A 1 145 ? -9.343  -32.919 3.553   1.00 25.67  ? 124 ALA A C   1 
ATOM   881   O  O   . ALA A 1 145 ? -8.100  -32.897 3.677   1.00 23.99  ? 124 ALA A O   1 
ATOM   882   C  CB  . ALA A 1 145 ? -10.691 -34.803 4.563   1.00 21.77  ? 124 ALA A CB  1 
ATOM   883   N  N   . GLU A 1 146 ? -9.964  -32.574 2.409   1.00 24.28  ? 125 GLU A N   1 
ATOM   884   C  CA  . GLU A 1 146 ? -9.218  -32.134 1.234   1.00 25.96  ? 125 GLU A CA  1 
ATOM   885   C  C   . GLU A 1 146 ? -8.472  -30.823 1.493   1.00 25.10  ? 125 GLU A C   1 
ATOM   886   O  O   . GLU A 1 146 ? -7.298  -30.691 1.122   1.00 24.42  ? 125 GLU A O   1 
ATOM   887   C  CB  . GLU A 1 146 ? -10.186 -31.987 0.052   1.00 28.41  ? 125 GLU A CB  1 
ATOM   888   C  CG  . GLU A 1 146 ? -9.573  -31.520 -1.243  1.00 50.16  ? 125 GLU A CG  1 
ATOM   889   C  CD  . GLU A 1 146 ? -10.625 -31.297 -2.327  1.00 60.40  ? 125 GLU A CD  1 
ATOM   890   O  OE1 . GLU A 1 146 ? -11.813 -31.650 -2.110  1.00 45.93  ? 125 GLU A OE1 1 
ATOM   891   O  OE2 . GLU A 1 146 ? -10.262 -30.760 -3.395  1.00 83.69  ? 125 GLU A OE2 1 
ATOM   892   N  N   . GLU A 1 147 ? -9.123  -29.846 2.152   1.00 21.23  ? 126 GLU A N   1 
ATOM   893   C  CA  . GLU A 1 147 ? -8.443  -28.564 2.387   1.00 20.04  ? 126 GLU A CA  1 
ATOM   894   C  C   . GLU A 1 147 ? -7.364  -28.687 3.454   1.00 19.63  ? 126 GLU A C   1 
ATOM   895   O  O   . GLU A 1 147 ? -6.326  -27.998 3.372   1.00 20.93  ? 126 GLU A O   1 
ATOM   896   C  CB  . GLU A 1 147 ? -9.452  -27.465 2.773   1.00 22.35  ? 126 GLU A CB  1 
ATOM   897   C  CG  . GLU A 1 147 ? -10.468 -27.093 1.681   1.00 22.70  ? 126 GLU A CG  1 
ATOM   898   C  CD  . GLU A 1 147 ? -9.847  -26.517 0.405   1.00 31.45  ? 126 GLU A CD  1 
ATOM   899   O  OE1 . GLU A 1 147 ? -8.652  -26.127 0.401   1.00 30.11  ? 126 GLU A OE1 1 
ATOM   900   O  OE2 . GLU A 1 147 ? -10.568 -26.457 -0.611  1.00 33.21  ? 126 GLU A OE2 1 
ATOM   901   N  N   . VAL A 1 148 ? -7.583  -29.525 4.469   1.00 19.62  ? 127 VAL A N   1 
ATOM   902   C  CA  . VAL A 1 148 ? -6.516  -29.768 5.451   1.00 21.77  ? 127 VAL A CA  1 
ATOM   903   C  C   . VAL A 1 148 ? -5.315  -30.435 4.788   1.00 23.31  ? 127 VAL A C   1 
ATOM   904   O  O   . VAL A 1 148 ? -4.154  -30.063 5.034   1.00 23.38  ? 127 VAL A O   1 
ATOM   905   C  CB  . VAL A 1 148 ? -7.051  -30.601 6.635   1.00 23.41  ? 127 VAL A CB  1 
ATOM   906   C  CG1 . VAL A 1 148 ? -5.890  -31.199 7.447   1.00 22.47  ? 127 VAL A CG1 1 
ATOM   907   C  CG2 . VAL A 1 148 ? -7.971  -29.734 7.540   1.00 22.83  ? 127 VAL A CG2 1 
ATOM   908   N  N   . GLU A 1 149 ? -5.563  -31.422 3.925   1.00 24.32  ? 128 GLU A N   1 
ATOM   909   C  CA  . GLU A 1 149 ? -4.454  -32.088 3.237   1.00 29.72  ? 128 GLU A CA  1 
ATOM   910   C  C   . GLU A 1 149 ? -3.660  -31.107 2.382   1.00 27.95  ? 128 GLU A C   1 
ATOM   911   O  O   . GLU A 1 149 ? -2.430  -31.195 2.294   1.00 26.82  ? 128 GLU A O   1 
ATOM   912   C  CB  . GLU A 1 149 ? -4.999  -33.238 2.393   1.00 34.55  ? 128 GLU A CB  1 
ATOM   913   C  CG  . GLU A 1 149 ? -3.966  -33.952 1.544   1.00 48.79  ? 128 GLU A CG  1 
ATOM   914   C  CD  . GLU A 1 149 ? -4.606  -34.946 0.571   1.00 81.05  ? 128 GLU A CD  1 
ATOM   915   O  OE1 . GLU A 1 149 ? -5.847  -34.888 0.370   1.00 74.79  ? 128 GLU A OE1 1 
ATOM   916   O  OE2 . GLU A 1 149 ? -3.867  -35.785 0.005   1.00 94.72  ? 128 GLU A OE2 1 
ATOM   917   N  N   . ARG A 1 150 ? -4.346  -30.170 1.734   1.00 24.70  ? 129 ARG A N   1 
ATOM   918   C  CA  . ARG A 1 150 ? -3.668  -29.146 0.948   1.00 26.86  ? 129 ARG A CA  1 
ATOM   919   C  C   . ARG A 1 150 ? -2.805  -28.238 1.825   1.00 30.48  ? 129 ARG A C   1 
ATOM   920   O  O   . ARG A 1 150 ? -1.684  -27.874 1.441   1.00 25.62  ? 129 ARG A O   1 
ATOM   921   C  CB  . ARG A 1 150 ? -4.730  -28.334 0.188   1.00 26.58  ? 129 ARG A CB  1 
ATOM   922   C  CG  . ARG A 1 150 ? -4.235  -27.171 -0.586  1.00 43.96  ? 129 ARG A CG  1 
ATOM   923   C  CD  . ARG A 1 150 ? -5.426  -26.592 -1.368  1.00 44.59  ? 129 ARG A CD  1 
ATOM   924   N  NE  . ARG A 1 150 ? -5.092  -25.310 -1.969  1.00 43.05  ? 129 ARG A NE  1 
ATOM   925   C  CZ  . ARG A 1 150 ? -5.987  -24.404 -2.334  1.00 50.86  ? 129 ARG A CZ  1 
ATOM   926   N  NH1 . ARG A 1 150 ? -7.283  -24.560 -2.070  1.00 34.77  ? 129 ARG A NH1 1 
ATOM   927   N  NH2 . ARG A 1 150 ? -5.576  -23.314 -2.976  1.00 53.47  ? 129 ARG A NH2 1 
ATOM   928   N  N   . ALA A 1 151 ? -3.315  -27.835 2.990   1.00 20.45  ? 130 ALA A N   1 
ATOM   929   C  CA  . ALA A 1 151 ? -2.505  -27.000 3.883   1.00 22.10  ? 130 ALA A CA  1 
ATOM   930   C  C   . ALA A 1 151 ? -1.248  -27.741 4.322   1.00 25.23  ? 130 ALA A C   1 
ATOM   931   O  O   . ALA A 1 151 ? -0.137  -27.182 4.314   1.00 27.00  ? 130 ALA A O   1 
ATOM   932   C  CB  . ALA A 1 151 ? -3.308  -26.586 5.113   1.00 21.77  ? 130 ALA A CB  1 
ATOM   933   N  N   . VAL A 1 152 ? -1.410  -29.011 4.691   1.00 23.86  ? 131 VAL A N   1 
ATOM   934   C  CA  . VAL A 1 152 ? -0.302  -29.798 5.220   1.00 25.08  ? 131 VAL A CA  1 
ATOM   935   C  C   . VAL A 1 152 ? 0.725   -30.064 4.133   1.00 27.10  ? 131 VAL A C   1 
ATOM   936   O  O   . VAL A 1 152 ? 1.934   -30.024 4.384   1.00 29.22  ? 131 VAL A O   1 
ATOM   937   C  CB  . VAL A 1 152 ? -0.833  -31.106 5.847   1.00 27.80  ? 131 VAL A CB  1 
ATOM   938   C  CG1 . VAL A 1 152 ? 0.324   -31.985 6.259   1.00 35.57  ? 131 VAL A CG1 1 
ATOM   939   C  CG2 . VAL A 1 152 ? -1.687  -30.782 7.056   1.00 31.70  ? 131 VAL A CG2 1 
ATOM   940   N  N   . ALA A 1 153 ? 0.268   -30.314 2.902   1.00 27.69  ? 132 ALA A N   1 
ATOM   941   C  CA  . ALA A 1 153 ? 1.215   -30.448 1.794   1.00 31.61  ? 132 ALA A CA  1 
ATOM   942   C  C   . ALA A 1 153 ? 2.022   -29.171 1.592   1.00 31.29  ? 132 ALA A C   1 
ATOM   943   O  O   . ALA A 1 153 ? 3.199   -29.230 1.199   1.00 28.49  ? 132 ALA A O   1 
ATOM   944   C  CB  . ALA A 1 153 ? 0.479   -30.831 0.507   1.00 32.07  ? 132 ALA A CB  1 
ATOM   945   N  N   . GLY A 1 154 ? 1.425   -28.008 1.868   1.00 26.23  ? 133 GLY A N   1 
ATOM   946   C  CA  . GLY A 1 154 ? 2.152   -26.759 1.773   1.00 25.13  ? 133 GLY A CA  1 
ATOM   947   C  C   . GLY A 1 154 ? 3.259   -26.624 2.801   1.00 28.23  ? 133 GLY A C   1 
ATOM   948   O  O   . GLY A 1 154 ? 4.134   -25.773 2.642   1.00 27.88  ? 133 GLY A O   1 
ATOM   949   N  N   . TRP A 1 155 ? 3.224   -27.431 3.867   1.00 23.76  ? 134 TRP A N   1 
ATOM   950   C  CA  . TRP A 1 155 ? 4.252   -27.390 4.910   1.00 20.85  ? 134 TRP A CA  1 
ATOM   951   C  C   . TRP A 1 155 ? 5.497   -28.210 4.557   1.00 26.72  ? 134 TRP A C   1 
ATOM   952   O  O   . TRP A 1 155 ? 6.496   -28.166 5.289   1.00 27.55  ? 134 TRP A O   1 
ATOM   953   C  CB  . TRP A 1 155 ? 3.655   -27.916 6.209   1.00 23.10  ? 134 TRP A CB  1 
ATOM   954   C  CG  . TRP A 1 155 ? 2.530   -27.103 6.744   1.00 22.62  ? 134 TRP A CG  1 
ATOM   955   C  CD1 . TRP A 1 155 ? 2.175   -25.830 6.382   1.00 22.57  ? 134 TRP A CD1 1 
ATOM   956   C  CD2 . TRP A 1 155 ? 1.625   -27.503 7.772   1.00 20.34  ? 134 TRP A CD2 1 
ATOM   957   N  NE1 . TRP A 1 155 ? 1.090   -25.411 7.143   1.00 23.00  ? 134 TRP A NE1 1 
ATOM   958   C  CE2 . TRP A 1 155 ? 0.728   -26.430 7.988   1.00 23.13  ? 134 TRP A CE2 1 
ATOM   959   C  CE3 . TRP A 1 155 ? 1.483   -28.676 8.534   1.00 24.51  ? 134 TRP A CE3 1 
ATOM   960   C  CZ2 . TRP A 1 155 ? -0.308  -26.493 8.950   1.00 23.45  ? 134 TRP A CZ2 1 
ATOM   961   C  CZ3 . TRP A 1 155 ? 0.451   -28.744 9.489   1.00 28.90  ? 134 TRP A CZ3 1 
ATOM   962   C  CH2 . TRP A 1 155 ? -0.423  -27.658 9.691   1.00 22.16  ? 134 TRP A CH2 1 
ATOM   963   N  N   . GLU A 1 156 ? 5.450   -28.977 3.486   1.00 24.04  ? 135 GLU A N   1 
ATOM   964   C  CA  . GLU A 1 156 ? 6.547   -29.890 3.166   1.00 25.29  ? 135 GLU A CA  1 
ATOM   965   C  C   . GLU A 1 156 ? 7.835   -29.125 2.869   1.00 27.74  ? 135 GLU A C   1 
ATOM   966   O  O   . GLU A 1 156 ? 7.907   -28.352 1.915   1.00 28.70  ? 135 GLU A O   1 
ATOM   967   C  CB  . GLU A 1 156 ? 6.146   -30.772 1.986   1.00 28.53  ? 135 GLU A CB  1 
ATOM   968   C  CG  . GLU A 1 156 ? 5.140   -31.848 2.411   1.00 40.18  ? 135 GLU A CG  1 
ATOM   969   C  CD  . GLU A 1 156 ? 4.435   -32.545 1.237   1.00 56.41  ? 135 GLU A CD  1 
ATOM   970   O  OE1 . GLU A 1 156 ? 4.725   -32.210 0.069   1.00 56.76  ? 135 GLU A OE1 1 
ATOM   971   O  OE2 . GLU A 1 156 ? 3.581   -33.428 1.494   1.00 49.11  ? 135 GLU A OE2 1 
ATOM   972   N  N   . GLY A 1 157 ? 8.849   -29.331 3.705   1.00 33.56  ? 136 GLY A N   1 
ATOM   973   C  CA  . GLY A 1 157 ? 10.102  -28.602 3.565   1.00 31.31  ? 136 GLY A CA  1 
ATOM   974   C  C   . GLY A 1 157 ? 10.002  -27.110 3.769   1.00 32.67  ? 136 GLY A C   1 
ATOM   975   O  O   . GLY A 1 157 ? 10.874  -26.383 3.305   1.00 33.11  ? 136 GLY A O   1 
ATOM   976   N  N   . ALA A 1 158 ? 8.958   -26.626 4.453   1.00 25.47  ? 137 ALA A N   1 
ATOM   977   C  CA  . ALA A 1 158 ? 8.641   -25.205 4.512   1.00 30.38  ? 137 ALA A CA  1 
ATOM   978   C  C   . ALA A 1 158 ? 8.157   -24.868 5.916   1.00 32.38  ? 137 ALA A C   1 
ATOM   979   O  O   . ALA A 1 158 ? 7.871   -25.756 6.719   1.00 35.15  ? 137 ALA A O   1 
ATOM   980   C  CB  . ALA A 1 158 ? 7.580   -24.819 3.477   1.00 31.72  ? 137 ALA A CB  1 
ATOM   981   N  N   . GLN A 1 159 ? 8.065   -23.571 6.217   1.00 26.25  ? 138 GLN A N   1 
ATOM   982   C  CA  . GLN A 1 159 ? 7.646   -23.109 7.537   1.00 30.03  ? 138 GLN A CA  1 
ATOM   983   C  C   . GLN A 1 159 ? 6.151   -22.807 7.513   1.00 30.58  ? 138 GLN A C   1 
ATOM   984   O  O   . GLN A 1 159 ? 5.728   -21.794 6.951   1.00 31.91  ? 138 GLN A O   1 
ATOM   985   C  CB  . GLN A 1 159 ? 8.442   -21.876 7.954   1.00 37.70  ? 138 GLN A CB  1 
ATOM   986   C  CG  . GLN A 1 159 ? 9.957   -22.142 7.997   1.00 52.16  ? 138 GLN A CG  1 
ATOM   987   C  CD  . GLN A 1 159 ? 10.331  -23.170 9.055   1.00 68.67  ? 138 GLN A CD  1 
ATOM   988   O  OE1 . GLN A 1 159 ? 9.852   -23.102 10.193  1.00 61.71  ? 138 GLN A OE1 1 
ATOM   989   N  NE2 . GLN A 1 159 ? 11.177  -24.138 8.683   1.00 63.70  ? 138 GLN A NE2 1 
ATOM   990   N  N   . GLY A 1 160 ? 5.355   -23.674 8.145   1.00 26.59  ? 139 GLY A N   1 
ATOM   991   C  CA  . GLY A 1 160 ? 3.926   -23.475 8.234   1.00 26.09  ? 139 GLY A CA  1 
ATOM   992   C  C   . GLY A 1 160 ? 3.514   -22.878 9.572   1.00 26.48  ? 139 GLY A C   1 
ATOM   993   O  O   . GLY A 1 160 ? 4.306   -22.676 10.490  1.00 24.31  ? 139 GLY A O   1 
ATOM   994   N  N   . ASN A 1 161 ? 2.216   -22.611 9.686   1.00 23.76  ? 140 ASN A N   1 
ATOM   995   C  CA  . ASN A 1 161 ? 1.655   -22.011 10.884  1.00 22.18  ? 140 ASN A CA  1 
ATOM   996   C  C   . ASN A 1 161 ? 0.299   -22.656 11.110  1.00 24.19  ? 140 ASN A C   1 
ATOM   997   O  O   . ASN A 1 161 ? -0.575  -22.497 10.256  1.00 24.54  ? 140 ASN A O   1 
ATOM   998   C  CB  . ASN A 1 161 ? 1.469   -20.499 10.701  1.00 24.86  ? 140 ASN A CB  1 
ATOM   999   C  CG  . ASN A 1 161 ? 1.076   -19.819 11.983  1.00 27.81  ? 140 ASN A CG  1 
ATOM   1000  O  OD1 . ASN A 1 161 ? -0.080  -19.847 12.380  1.00 22.20  ? 140 ASN A OD1 1 
ATOM   1001  N  ND2 . ASN A 1 161 ? 2.061   -19.261 12.682  1.00 30.15  ? 140 ASN A ND2 1 
ATOM   1002  N  N   . VAL A 1 162 ? 0.115   -23.381 12.226  1.00 20.47  ? 141 VAL A N   1 
ATOM   1003  C  CA  . VAL A 1 162 ? -1.126  -24.159 12.381  1.00 19.98  ? 141 VAL A CA  1 
ATOM   1004  C  C   . VAL A 1 162 ? -2.326  -23.227 12.391  1.00 21.99  ? 141 VAL A C   1 
ATOM   1005  O  O   . VAL A 1 162 ? -3.301  -23.434 11.659  1.00 20.83  ? 141 VAL A O   1 
ATOM   1006  C  CB  . VAL A 1 162 ? -1.107  -25.034 13.655  1.00 21.14  ? 141 VAL A CB  1 
ATOM   1007  C  CG1 . VAL A 1 162 ? -2.441  -25.791 13.766  1.00 21.31  ? 141 VAL A CG1 1 
ATOM   1008  C  CG2 . VAL A 1 162 ? 0.038   -26.081 13.609  1.00 19.32  ? 141 VAL A CG2 1 
ATOM   1009  N  N   . PHE A 1 163 ? -2.293  -22.210 13.250  1.00 19.59  ? 142 PHE A N   1 
ATOM   1010  C  CA  . PHE A 1 163 ? -3.444  -21.309 13.353  1.00 17.81  ? 142 PHE A CA  1 
ATOM   1011  C  C   . PHE A 1 163 ? -3.781  -20.658 12.009  1.00 21.01  ? 142 PHE A C   1 
ATOM   1012  O  O   . PHE A 1 163 ? -4.934  -20.711 11.555  1.00 21.03  ? 142 PHE A O   1 
ATOM   1013  C  CB  . PHE A 1 163 ? -3.190  -20.223 14.407  1.00 20.90  ? 142 PHE A CB  1 
ATOM   1014  C  CG  . PHE A 1 163 ? -4.282  -19.214 14.447  1.00 20.30  ? 142 PHE A CG  1 
ATOM   1015  C  CD1 . PHE A 1 163 ? -5.521  -19.584 14.934  1.00 18.46  ? 142 PHE A CD1 1 
ATOM   1016  C  CD2 . PHE A 1 163 ? -4.102  -17.939 13.927  1.00 25.09  ? 142 PHE A CD2 1 
ATOM   1017  C  CE1 . PHE A 1 163 ? -6.594  -18.662 14.944  1.00 23.04  ? 142 PHE A CE1 1 
ATOM   1018  C  CE2 . PHE A 1 163 ? -5.140  -17.030 13.935  1.00 27.23  ? 142 PHE A CE2 1 
ATOM   1019  C  CZ  . PHE A 1 163 ? -6.388  -17.406 14.434  1.00 21.93  ? 142 PHE A CZ  1 
ATOM   1020  N  N   . GLU A 1 164 ? -2.797  -20.026 11.353  1.00 20.43  ? 143 GLU A N   1 
ATOM   1021  C  CA  . GLU A 1 164 ? -3.116  -19.307 10.115  1.00 23.32  ? 143 GLU A CA  1 
ATOM   1022  C  C   . GLU A 1 164 ? -3.480  -20.263 8.981   1.00 24.09  ? 143 GLU A C   1 
ATOM   1023  O  O   . GLU A 1 164 ? -4.433  -20.008 8.239   1.00 21.89  ? 143 GLU A O   1 
ATOM   1024  C  CB  . GLU A 1 164 ? -1.938  -18.426 9.681   1.00 25.32  ? 143 GLU A CB  1 
ATOM   1025  C  CG  . GLU A 1 164 ? -1.611  -17.327 10.686  1.00 28.86  ? 143 GLU A CG  1 
ATOM   1026  C  CD  . GLU A 1 164 ? -2.628  -16.184 10.700  1.00 48.02  ? 143 GLU A CD  1 
ATOM   1027  O  OE1 . GLU A 1 164 ? -3.437  -16.094 9.746   1.00 40.97  ? 143 GLU A OE1 1 
ATOM   1028  O  OE2 . GLU A 1 164 ? -2.616  -15.380 11.668  1.00 45.26  ? 143 GLU A OE2 1 
ATOM   1029  N  N   . ASP A 1 165 ? -2.734  -21.354 8.821   1.00 22.16  ? 144 ASP A N   1 
ATOM   1030  C  CA  . ASP A 1 165 ? -2.951  -22.196 7.646   1.00 19.33  ? 144 ASP A CA  1 
ATOM   1031  C  C   . ASP A 1 165 ? -4.171  -23.108 7.813   1.00 20.67  ? 144 ASP A C   1 
ATOM   1032  O  O   . ASP A 1 165 ? -4.871  -23.385 6.827   1.00 20.31  ? 144 ASP A O   1 
ATOM   1033  C  CB  . ASP A 1 165 ? -1.693  -23.033 7.346   1.00 20.61  ? 144 ASP A CB  1 
ATOM   1034  C  CG  . ASP A 1 165 ? -0.450  -22.157 7.118   1.00 25.56  ? 144 ASP A CG  1 
ATOM   1035  O  OD1 . ASP A 1 165 ? -0.628  -20.934 6.861   1.00 26.55  ? 144 ASP A OD1 1 
ATOM   1036  O  OD2 . ASP A 1 165 ? 0.680   -22.681 7.192   1.00 23.09  ? 144 ASP A OD2 1 
ATOM   1037  N  N   . LEU A 1 166 ? -4.421  -23.650 9.022   1.00 19.43  ? 145 LEU A N   1 
ATOM   1038  C  CA  . LEU A 1 166 ? -5.617  -24.489 9.139   1.00 19.83  ? 145 LEU A CA  1 
ATOM   1039  C  C   . LEU A 1 166 ? -6.881  -23.647 9.259   1.00 23.01  ? 145 LEU A C   1 
ATOM   1040  O  O   . LEU A 1 166 ? -7.950  -24.088 8.822   1.00 20.00  ? 145 LEU A O   1 
ATOM   1041  C  CB  . LEU A 1 166 ? -5.516  -25.461 10.312  1.00 18.91  ? 145 LEU A CB  1 
ATOM   1042  C  CG  . LEU A 1 166 ? -4.424  -26.499 10.123  1.00 18.06  ? 145 LEU A CG  1 
ATOM   1043  C  CD1 . LEU A 1 166 ? -4.555  -27.615 11.206  1.00 24.14  ? 145 LEU A CD1 1 
ATOM   1044  C  CD2 . LEU A 1 166 ? -4.377  -27.093 8.687   1.00 22.70  ? 145 LEU A CD2 1 
ATOM   1045  N  N   . SER A 1 167 ? -6.785  -22.420 9.771   1.00 18.11  ? 146 SER A N   1 
ATOM   1046  C  CA  . SER A 1 167 ? -7.973  -21.549 9.733   1.00 21.28  ? 146 SER A CA  1 
ATOM   1047  C  C   . SER A 1 167 ? -8.357  -21.261 8.293   1.00 21.16  ? 146 SER A C   1 
ATOM   1048  O  O   . SER A 1 167 ? -9.547  -21.259 7.928   1.00 19.93  ? 146 SER A O   1 
ATOM   1049  C  CB  . SER A 1 167 ? -7.717  -20.215 10.475  1.00 18.46  ? 146 SER A CB  1 
ATOM   1050  O  OG  . SER A 1 167 ? -7.580  -20.415 11.867  1.00 21.24  ? 146 SER A OG  1 
ATOM   1051  N  N   . LEU A 1 168 ? -7.355  -21.006 7.456   1.00 21.73  ? 147 LEU A N   1 
ATOM   1052  C  CA  . LEU A 1 168 ? -7.614  -20.808 6.028   1.00 21.28  ? 147 LEU A CA  1 
ATOM   1053  C  C   . LEU A 1 168 ? -8.232  -22.055 5.397   1.00 24.42  ? 147 LEU A C   1 
ATOM   1054  O  O   . LEU A 1 168 ? -9.208  -21.963 4.642   1.00 21.33  ? 147 LEU A O   1 
ATOM   1055  C  CB  . LEU A 1 168 ? -6.295  -20.418 5.334   1.00 19.27  ? 147 LEU A CB  1 
ATOM   1056  C  CG  . LEU A 1 168 ? -6.433  -20.170 3.814   1.00 27.47  ? 147 LEU A CG  1 
ATOM   1057  C  CD1 . LEU A 1 168 ? -7.534  -19.133 3.480   1.00 25.03  ? 147 LEU A CD1 1 
ATOM   1058  C  CD2 . LEU A 1 168 ? -5.088  -19.730 3.226   1.00 31.34  ? 147 LEU A CD2 1 
ATOM   1059  N  N   . ALA A 1 169 ? -7.660  -23.231 5.675   1.00 18.77  ? 148 ALA A N   1 
ATOM   1060  C  CA  . ALA A 1 169 ? -8.214  -24.480 5.142   1.00 20.08  ? 148 ALA A CA  1 
ATOM   1061  C  C   . ALA A 1 169 ? -9.676  -24.657 5.562   1.00 22.11  ? 148 ALA A C   1 
ATOM   1062  O  O   . ALA A 1 169 ? -10.519 -25.024 4.746   1.00 21.86  ? 148 ALA A O   1 
ATOM   1063  C  CB  . ALA A 1 169 ? -7.384  -25.669 5.617   1.00 21.34  ? 148 ALA A CB  1 
ATOM   1064  N  N   . PHE A 1 170 ? -9.992  -24.403 6.839   1.00 21.34  ? 149 PHE A N   1 
ATOM   1065  C  CA  . PHE A 1 170 ? -11.378 -24.524 7.297   1.00 20.92  ? 149 PHE A CA  1 
ATOM   1066  C  C   . PHE A 1 170 ? -12.285 -23.545 6.553   1.00 21.33  ? 149 PHE A C   1 
ATOM   1067  O  O   . PHE A 1 170 ? -13.424 -23.881 6.206   1.00 19.99  ? 149 PHE A O   1 
ATOM   1068  C  CB  . PHE A 1 170 ? -11.475 -24.242 8.808   1.00 17.43  ? 149 PHE A CB  1 
ATOM   1069  C  CG  . PHE A 1 170 ? -10.731 -25.231 9.668   1.00 20.32  ? 149 PHE A CG  1 
ATOM   1070  C  CD1 . PHE A 1 170 ? -10.520 -26.541 9.237   1.00 19.34  ? 149 PHE A CD1 1 
ATOM   1071  C  CD2 . PHE A 1 170 ? -10.299 -24.850 10.940  1.00 18.26  ? 149 PHE A CD2 1 
ATOM   1072  C  CE1 . PHE A 1 170 ? -9.848  -27.475 10.047  1.00 22.58  ? 149 PHE A CE1 1 
ATOM   1073  C  CE2 . PHE A 1 170 ? -9.644  -25.796 11.773  1.00 21.09  ? 149 PHE A CE2 1 
ATOM   1074  C  CZ  . PHE A 1 170 ? -9.410  -27.088 11.296  1.00 20.11  ? 149 PHE A CZ  1 
ATOM   1075  N  N   . GLY A 1 171 ? -11.815 -22.311 6.363   1.00 21.20  ? 150 GLY A N   1 
ATOM   1076  C  CA  . GLY A 1 171 ? -12.616 -21.334 5.638   1.00 23.97  ? 150 GLY A CA  1 
ATOM   1077  C  C   . GLY A 1 171 ? -12.841 -21.716 4.185   1.00 20.04  ? 150 GLY A C   1 
ATOM   1078  O  O   . GLY A 1 171 ? -13.944 -21.534 3.642   1.00 21.45  ? 150 GLY A O   1 
ATOM   1079  N  N   . ARG A 1 172 ? -11.799 -22.204 3.521   1.00 16.85  ? 151 ARG A N   1 
ATOM   1080  C  CA  . ARG A 1 172 ? -11.989 -22.684 2.156   1.00 23.29  ? 151 ARG A CA  1 
ATOM   1081  C  C   . ARG A 1 172 ? -13.028 -23.801 2.120   1.00 26.71  ? 151 ARG A C   1 
ATOM   1082  O  O   . ARG A 1 172 ? -13.912 -23.810 1.254   1.00 22.26  ? 151 ARG A O   1 
ATOM   1083  C  CB  . ARG A 1 172 ? -10.655 -23.167 1.595   1.00 20.18  ? 151 ARG A CB  1 
ATOM   1084  C  CG  . ARG A 1 172 ? -9.674  -22.027 1.298   1.00 20.68  ? 151 ARG A CG  1 
ATOM   1085  C  CD  . ARG A 1 172 ? -8.316  -22.655 0.992   1.00 27.44  ? 151 ARG A CD  1 
ATOM   1086  N  NE  . ARG A 1 172 ? -7.320  -21.689 0.560   1.00 27.23  ? 151 ARG A NE  1 
ATOM   1087  C  CZ  . ARG A 1 172 ? -6.048  -21.997 0.350   1.00 32.54  ? 151 ARG A CZ  1 
ATOM   1088  N  NH1 . ARG A 1 172 ? -5.579  -23.199 0.615   1.00 33.10  ? 151 ARG A NH1 1 
ATOM   1089  N  NH2 . ARG A 1 172 ? -5.236  -21.083 -0.175  1.00 33.42  ? 151 ARG A NH2 1 
ATOM   1090  N  N   . ALA A 1 173 ? -12.953 -24.746 3.071   1.00 18.91  ? 152 ALA A N   1 
ATOM   1091  C  CA  . ALA A 1 173 ? -13.923 -25.833 3.082   1.00 21.26  ? 152 ALA A CA  1 
ATOM   1092  C  C   . ALA A 1 173 ? -15.327 -25.309 3.359   1.00 22.81  ? 152 ALA A C   1 
ATOM   1093  O  O   . ALA A 1 173 ? -16.312 -25.782 2.764   1.00 19.55  ? 152 ALA A O   1 
ATOM   1094  C  CB  . ALA A 1 173 ? -13.519 -26.892 4.125   1.00 21.30  ? 152 ALA A CB  1 
ATOM   1095  N  N   . ALA A 1 174 ? -15.437 -24.320 4.246   1.00 21.99  ? 153 ALA A N   1 
ATOM   1096  C  CA  . ALA A 1 174 ? -16.752 -23.806 4.603   1.00 23.66  ? 153 ALA A CA  1 
ATOM   1097  C  C   . ALA A 1 174 ? -17.416 -23.110 3.420   1.00 24.10  ? 153 ALA A C   1 
ATOM   1098  O  O   . ALA A 1 174 ? -18.631 -23.275 3.218   1.00 21.00  ? 153 ALA A O   1 
ATOM   1099  C  CB  . ALA A 1 174 ? -16.634 -22.860 5.806   1.00 20.00  ? 153 ALA A CB  1 
ATOM   1100  N  N   . PHE A 1 175 ? -16.654 -22.300 2.653   1.00 21.55  ? 154 PHE A N   1 
ATOM   1101  C  CA  . PHE A 1 175 ? -17.223 -21.625 1.481   1.00 24.11  ? 154 PHE A CA  1 
ATOM   1102  C  C   . PHE A 1 175 ? -17.647 -22.642 0.427   1.00 24.22  ? 154 PHE A C   1 
ATOM   1103  O  O   . PHE A 1 175 ? -18.765 -22.572 -0.086  1.00 24.49  ? 154 PHE A O   1 
ATOM   1104  C  CB  . PHE A 1 175 ? -16.235 -20.616 0.862   1.00 22.76  ? 154 PHE A CB  1 
ATOM   1105  C  CG  . PHE A 1 175 ? -16.205 -19.253 1.556   1.00 26.42  ? 154 PHE A CG  1 
ATOM   1106  C  CD1 . PHE A 1 175 ? -16.239 -19.152 2.934   1.00 28.47  ? 154 PHE A CD1 1 
ATOM   1107  C  CD2 . PHE A 1 175 ? -16.130 -18.077 0.803   1.00 27.47  ? 154 PHE A CD2 1 
ATOM   1108  C  CE1 . PHE A 1 175 ? -16.201 -17.904 3.571   1.00 26.34  ? 154 PHE A CE1 1 
ATOM   1109  C  CE2 . PHE A 1 175 ? -16.119 -16.827 1.422   1.00 22.40  ? 154 PHE A CE2 1 
ATOM   1110  C  CZ  . PHE A 1 175 ? -16.148 -16.739 2.816   1.00 25.09  ? 154 PHE A CZ  1 
ATOM   1111  N  N   . ARG A 1 176 ? -16.778 -23.620 0.114   1.00 21.30  ? 155 ARG A N   1 
ATOM   1112  C  CA  . ARG A 1 176 ? -17.180 -24.671 -0.823  1.00 22.99  ? 155 ARG A CA  1 
ATOM   1113  C  C   . ARG A 1 176 ? -18.415 -25.421 -0.306  1.00 27.68  ? 155 ARG A C   1 
ATOM   1114  O  O   . ARG A 1 176 ? -19.369 -25.658 -1.054  1.00 26.00  ? 155 ARG A O   1 
ATOM   1115  C  CB  . ARG A 1 176 ? -16.017 -25.645 -1.080  1.00 23.48  ? 155 ARG A CB  1 
ATOM   1116  C  CG  . ARG A 1 176 ? -14.820 -24.992 -1.790  1.00 25.71  ? 155 ARG A CG  1 
ATOM   1117  C  CD  . ARG A 1 176 ? -13.639 -25.958 -1.954  1.00 27.56  ? 155 ARG A CD  1 
ATOM   1118  N  NE  . ARG A 1 176 ? -14.023 -27.169 -2.689  1.00 29.07  ? 155 ARG A NE  1 
ATOM   1119  C  CZ  . ARG A 1 176 ? -13.328 -28.304 -2.664  1.00 34.34  ? 155 ARG A CZ  1 
ATOM   1120  N  NH1 . ARG A 1 176 ? -12.264 -28.450 -1.885  1.00 35.02  ? 155 ARG A NH1 1 
ATOM   1121  N  NH2 . ARG A 1 176 ? -13.718 -29.328 -3.426  1.00 35.47  ? 155 ARG A NH2 1 
ATOM   1122  N  N   . TRP A 1 177 ? -18.431 -25.757 0.976   1.00 21.56  ? 156 TRP A N   1 
ATOM   1123  C  CA  . TRP A 1 177 ? -19.562 -26.487 1.562   1.00 21.69  ? 156 TRP A CA  1 
ATOM   1124  C  C   . TRP A 1 177 ? -20.862 -25.700 1.434   1.00 23.70  ? 156 TRP A C   1 
ATOM   1125  O  O   . TRP A 1 177 ? -21.915 -26.271 1.117   1.00 24.31  ? 156 TRP A O   1 
ATOM   1126  C  CB  . TRP A 1 177 ? -19.262 -26.807 3.037   1.00 22.27  ? 156 TRP A CB  1 
ATOM   1127  C  CG  . TRP A 1 177 ? -20.456 -27.312 3.793   1.00 22.47  ? 156 TRP A CG  1 
ATOM   1128  C  CD1 . TRP A 1 177 ? -21.007 -28.576 3.734   1.00 21.21  ? 156 TRP A CD1 1 
ATOM   1129  C  CD2 . TRP A 1 177 ? -21.243 -26.575 4.729   1.00 20.37  ? 156 TRP A CD2 1 
ATOM   1130  N  NE1 . TRP A 1 177 ? -22.070 -28.660 4.592   1.00 20.76  ? 156 TRP A NE1 1 
ATOM   1131  C  CE2 . TRP A 1 177 ? -22.238 -27.454 5.219   1.00 25.90  ? 156 TRP A CE2 1 
ATOM   1132  C  CE3 . TRP A 1 177 ? -21.186 -25.254 5.225   1.00 20.90  ? 156 TRP A CE3 1 
ATOM   1133  C  CZ2 . TRP A 1 177 ? -23.170 -27.065 6.177   1.00 24.37  ? 156 TRP A CZ2 1 
ATOM   1134  C  CZ3 . TRP A 1 177 ? -22.114 -24.859 6.152   1.00 23.82  ? 156 TRP A CZ3 1 
ATOM   1135  C  CH2 . TRP A 1 177 ? -23.105 -25.765 6.627   1.00 21.52  ? 156 TRP A CH2 1 
ATOM   1136  N  N   . ALA A 1 178 ? -20.812 -24.398 1.671   1.00 21.68  ? 157 ALA A N   1 
ATOM   1137  C  CA  . ALA A 1 178 ? -22.006 -23.558 1.668   1.00 21.69  ? 157 ALA A CA  1 
ATOM   1138  C  C   . ALA A 1 178 ? -22.486 -23.207 0.259   1.00 23.48  ? 157 ALA A C   1 
ATOM   1139  O  O   . ALA A 1 178 ? -23.576 -22.632 0.117   1.00 23.72  ? 157 ALA A O   1 
ATOM   1140  C  CB  . ALA A 1 178 ? -21.736 -22.273 2.470   1.00 22.00  ? 157 ALA A CB  1 
ATOM   1141  N  N   . GLY A 1 179 ? -21.713 -23.549 -0.778  1.00 24.76  ? 158 GLY A N   1 
ATOM   1142  C  CA  . GLY A 1 179 ? -22.058 -23.148 -2.134  1.00 27.63  ? 158 GLY A CA  1 
ATOM   1143  C  C   . GLY A 1 179 ? -21.704 -21.725 -2.489  1.00 32.86  ? 158 GLY A C   1 
ATOM   1144  O  O   . GLY A 1 179 ? -22.280 -21.168 -3.434  1.00 27.36  ? 158 GLY A O   1 
ATOM   1145  N  N   . ILE A 1 180 ? -20.778 -21.104 -1.761  1.00 24.70  ? 159 ILE A N   1 
ATOM   1146  C  CA  . ILE A 1 180 ? -20.285 -19.772 -2.106  1.00 26.68  ? 159 ILE A CA  1 
ATOM   1147  C  C   . ILE A 1 180 ? -19.173 -19.983 -3.119  1.00 34.37  ? 159 ILE A C   1 
ATOM   1148  O  O   . ILE A 1 180 ? -18.082 -20.433 -2.767  1.00 33.54  ? 159 ILE A O   1 
ATOM   1149  C  CB  . ILE A 1 180 ? -19.768 -19.009 -0.885  1.00 29.55  ? 159 ILE A CB  1 
ATOM   1150  C  CG1 . ILE A 1 180 ? -20.867 -18.888 0.180   1.00 31.66  ? 159 ILE A CG1 1 
ATOM   1151  C  CG2 . ILE A 1 180 ? -19.217 -17.621 -1.295  1.00 24.71  ? 159 ILE A CG2 1 
ATOM   1152  C  CD1 . ILE A 1 180 ? -20.320 -18.423 1.529   1.00 25.39  ? 159 ILE A CD1 1 
ATOM   1153  N  N   . ASP A 1 181 ? -19.444 -19.682 -4.364  1.00 28.47  ? 160 ASP A N   1 
ATOM   1154  C  CA  . ASP A 1 181 ? -18.553 -20.072 -5.457  1.00 35.35  ? 160 ASP A CA  1 
ATOM   1155  C  C   . ASP A 1 181 ? -17.842 -18.823 -5.971  1.00 33.85  ? 160 ASP A C   1 
ATOM   1156  O  O   . ASP A 1 181 ? -18.406 -18.048 -6.745  1.00 35.51  ? 160 ASP A O   1 
ATOM   1157  C  CB  . ASP A 1 181 ? -19.338 -20.770 -6.566  1.00 45.70  ? 160 ASP A CB  1 
ATOM   1158  C  CG  . ASP A 1 181 ? -18.524 -20.928 -7.845  1.00 74.48  ? 160 ASP A CG  1 
ATOM   1159  O  OD1 . ASP A 1 181 ? -17.518 -21.674 -7.830  1.00 78.43  ? 160 ASP A OD1 1 
ATOM   1160  O  OD2 . ASP A 1 181 ? -18.887 -20.301 -8.866  1.00 87.51  ? 160 ASP A OD2 1 
ATOM   1161  N  N   . LEU A 1 182 ? -16.617 -18.607 -5.521  1.00 32.57  ? 161 LEU A N   1 
ATOM   1162  C  CA  . LEU A 1 182 ? -15.843 -17.441 -5.904  1.00 32.91  ? 161 LEU A CA  1 
ATOM   1163  C  C   . LEU A 1 182 ? -14.508 -17.908 -6.449  1.00 32.51  ? 161 LEU A C   1 
ATOM   1164  O  O   . LEU A 1 182 ? -14.079 -19.029 -6.170  1.00 28.36  ? 161 LEU A O   1 
ATOM   1165  C  CB  . LEU A 1 182 ? -15.608 -16.500 -4.715  1.00 31.24  ? 161 LEU A CB  1 
ATOM   1166  C  CG  . LEU A 1 182 ? -16.864 -15.972 -4.047  1.00 38.15  ? 161 LEU A CG  1 
ATOM   1167  C  CD1 . LEU A 1 182 ? -16.496 -15.356 -2.697  1.00 28.12  ? 161 LEU A CD1 1 
ATOM   1168  C  CD2 . LEU A 1 182 ? -17.528 -14.957 -4.962  1.00 37.58  ? 161 LEU A CD2 1 
ATOM   1169  N  N   . PRO A 1 183 ? -13.826 -17.069 -7.222  1.00 31.95  ? 162 PRO A N   1 
ATOM   1170  C  CA  . PRO A 1 183 ? -12.420 -17.341 -7.545  1.00 31.80  ? 162 PRO A CA  1 
ATOM   1171  C  C   . PRO A 1 183 ? -11.595 -17.565 -6.277  1.00 33.75  ? 162 PRO A C   1 
ATOM   1172  O  O   . PRO A 1 183 ? -11.871 -16.993 -5.216  1.00 32.13  ? 162 PRO A O   1 
ATOM   1173  C  CB  . PRO A 1 183 ? -11.974 -16.069 -8.276  1.00 34.30  ? 162 PRO A CB  1 
ATOM   1174  C  CG  . PRO A 1 183 ? -13.230 -15.401 -8.735  1.00 40.91  ? 162 PRO A CG  1 
ATOM   1175  C  CD  . PRO A 1 183 ? -14.278 -15.756 -7.727  1.00 32.47  ? 162 PRO A CD  1 
ATOM   1176  N  N   . ALA A 1 184 ? -10.536 -18.365 -6.410  1.00 34.28  ? 163 ALA A N   1 
ATOM   1177  C  CA  . ALA A 1 184 ? -9.739  -18.748 -5.245  1.00 34.70  ? 163 ALA A CA  1 
ATOM   1178  C  C   . ALA A 1 184 ? -9.177  -17.525 -4.520  1.00 36.29  ? 163 ALA A C   1 
ATOM   1179  O  O   . ALA A 1 184 ? -9.144  -17.482 -3.285  1.00 33.75  ? 163 ALA A O   1 
ATOM   1180  C  CB  . ALA A 1 184 ? -8.615  -19.683 -5.674  1.00 41.39  ? 163 ALA A CB  1 
ATOM   1181  N  N   . GLU A 1 185 ? -8.712  -16.529 -5.276  1.00 29.46  ? 164 GLU A N   1 
ATOM   1182  C  CA  . GLU A 1 185 ? -8.134  -15.340 -4.665  1.00 30.85  ? 164 GLU A CA  1 
ATOM   1183  C  C   . GLU A 1 185 ? -9.156  -14.605 -3.806  1.00 31.93  ? 164 GLU A C   1 
ATOM   1184  O  O   . GLU A 1 185 ? -8.829  -14.109 -2.721  1.00 28.46  ? 164 GLU A O   1 
ATOM   1185  C  CB  . GLU A 1 185 ? -7.582  -14.417 -5.751  1.00 44.74  ? 164 GLU A CB  1 
ATOM   1186  C  CG  . GLU A 1 185 ? -6.482  -15.053 -6.649  1.00 75.60  ? 164 GLU A CG  1 
ATOM   1187  C  CD  . GLU A 1 185 ? -6.958  -16.197 -7.596  1.00 85.98  ? 164 GLU A CD  1 
ATOM   1188  O  OE1 . GLU A 1 185 ? -8.145  -16.226 -8.047  1.00 41.25  ? 164 GLU A OE1 1 
ATOM   1189  O  OE2 . GLU A 1 185 ? -6.107  -17.077 -7.890  1.00 71.99  ? 164 GLU A OE2 1 
ATOM   1190  N  N   . ASN A 1 186 ? -10.399 -14.509 -4.278  1.00 27.82  ? 165 ASN A N   1 
ATOM   1191  C  CA  . ASN A 1 186 ? -11.419 -13.808 -3.511  1.00 29.98  ? 165 ASN A CA  1 
ATOM   1192  C  C   . ASN A 1 186 ? -11.794 -14.569 -2.248  1.00 27.70  ? 165 ASN A C   1 
ATOM   1193  O  O   . ASN A 1 186 ? -12.043 -13.962 -1.193  1.00 28.34  ? 165 ASN A O   1 
ATOM   1194  C  CB  . ASN A 1 186 ? -12.671 -13.614 -4.358  1.00 32.01  ? 165 ASN A CB  1 
ATOM   1195  C  CG  . ASN A 1 186 ? -12.414 -12.787 -5.585  1.00 44.71  ? 165 ASN A CG  1 
ATOM   1196  O  OD1 . ASN A 1 186 ? -11.699 -13.211 -6.499  1.00 47.35  ? 165 ASN A OD1 1 
ATOM   1197  N  ND2 . ASN A 1 186 ? -12.991 -11.597 -5.621  1.00 46.51  ? 165 ASN A ND2 1 
ATOM   1198  N  N   . THR A 1 187 ? -11.940 -15.886 -2.360  1.00 24.96  ? 166 THR A N   1 
ATOM   1199  C  CA  . THR A 1 187 ? -12.253 -16.684 -1.179  1.00 24.49  ? 166 THR A CA  1 
ATOM   1200  C  C   . THR A 1 187 ? -11.177 -16.520 -0.118  1.00 28.52  ? 166 THR A C   1 
ATOM   1201  O  O   . THR A 1 187 ? -11.483 -16.297 1.052   1.00 24.32  ? 166 THR A O   1 
ATOM   1202  C  CB  . THR A 1 187 ? -12.407 -18.160 -1.522  1.00 28.70  ? 166 THR A CB  1 
ATOM   1203  O  OG1 . THR A 1 187 ? -13.604 -18.342 -2.273  1.00 35.23  ? 166 THR A OG1 1 
ATOM   1204  C  CG2 . THR A 1 187 ? -12.526 -18.991 -0.237  1.00 27.22  ? 166 THR A CG2 1 
ATOM   1205  N  N   . ASP A 1 188 ? -9.908  -16.627 -0.515  1.00 25.50  ? 167 ASP A N   1 
ATOM   1206  C  CA  . ASP A 1 188 ? -8.836  -16.523 0.472   1.00 25.88  ? 167 ASP A CA  1 
ATOM   1207  C  C   . ASP A 1 188 ? -8.847  -15.166 1.147   1.00 27.87  ? 167 ASP A C   1 
ATOM   1208  O  O   . ASP A 1 188 ? -8.617  -15.055 2.368   1.00 27.26  ? 167 ASP A O   1 
ATOM   1209  C  CB  . ASP A 1 188 ? -7.489  -16.780 -0.194  1.00 23.63  ? 167 ASP A CB  1 
ATOM   1210  C  CG  . ASP A 1 188 ? -7.278  -18.240 -0.530  1.00 38.27  ? 167 ASP A CG  1 
ATOM   1211  O  OD1 . ASP A 1 188 ? -8.180  -19.064 -0.232  1.00 34.66  ? 167 ASP A OD1 1 
ATOM   1212  O  OD2 . ASP A 1 188 ? -6.212  -18.571 -1.084  1.00 40.53  ? 167 ASP A OD2 1 
ATOM   1213  N  N   . GLU A 1 189 ? -9.117  -14.117 0.374   1.00 22.99  ? 168 GLU A N   1 
ATOM   1214  C  CA  . GLU A 1 189 ? -9.136  -12.791 0.965   1.00 25.56  ? 168 GLU A CA  1 
ATOM   1215  C  C   . GLU A 1 189 ? -10.274 -12.654 1.964   1.00 25.53  ? 168 GLU A C   1 
ATOM   1216  O  O   . GLU A 1 189 ? -10.087 -12.053 3.019   1.00 22.53  ? 168 GLU A O   1 
ATOM   1217  C  CB  . GLU A 1 189 ? -9.238  -11.720 -0.118  1.00 26.03  ? 168 GLU A CB  1 
ATOM   1218  C  CG  . GLU A 1 189 ? -9.435  -10.324 0.473   1.00 33.83  ? 168 GLU A CG  1 
ATOM   1219  C  CD  . GLU A 1 189 ? -9.521  -9.248  -0.587  1.00 58.76  ? 168 GLU A CD  1 
ATOM   1220  O  OE1 . GLU A 1 189 ? -9.473  -9.594  -1.789  1.00 74.30  ? 168 GLU A OE1 1 
ATOM   1221  O  OE2 . GLU A 1 189 ? -9.635  -8.056  -0.213  1.00 69.81  ? 168 GLU A OE2 1 
ATOM   1222  N  N   . LEU A 1 190 ? -11.463 -13.190 1.640   1.00 22.56  ? 169 LEU A N   1 
ATOM   1223  C  CA  . LEU A 1 190 ? -12.593 -13.103 2.560   1.00 22.38  ? 169 LEU A CA  1 
ATOM   1224  C  C   . LEU A 1 190 ? -12.344 -13.938 3.811   1.00 23.49  ? 169 LEU A C   1 
ATOM   1225  O  O   . LEU A 1 190 ? -12.670 -13.523 4.932   1.00 19.97  ? 169 LEU A O   1 
ATOM   1226  C  CB  . LEU A 1 190 ? -13.867 -13.565 1.855   1.00 24.47  ? 169 LEU A CB  1 
ATOM   1227  C  CG  . LEU A 1 190 ? -14.340 -12.560 0.790   1.00 26.22  ? 169 LEU A CG  1 
ATOM   1228  C  CD1 . LEU A 1 190 ? -15.421 -13.183 -0.074  1.00 26.80  ? 169 LEU A CD1 1 
ATOM   1229  C  CD2 . LEU A 1 190 ? -14.892 -11.257 1.429   1.00 24.94  ? 169 LEU A CD2 1 
ATOM   1230  N  N   . VAL A 1 191 ? -11.819 -15.146 3.633   1.00 23.82  ? 170 VAL A N   1 
ATOM   1231  C  CA  . VAL A 1 191 ? -11.497 -15.952 4.802   1.00 22.47  ? 170 VAL A CA  1 
ATOM   1232  C  C   . VAL A 1 191 ? -10.446 -15.241 5.641   1.00 23.94  ? 170 VAL A C   1 
ATOM   1233  O  O   . VAL A 1 191 ? -10.533 -15.222 6.876   1.00 21.63  ? 170 VAL A O   1 
ATOM   1234  C  CB  . VAL A 1 191 ? -11.063 -17.364 4.377   1.00 20.79  ? 170 VAL A CB  1 
ATOM   1235  C  CG1 . VAL A 1 191 ? -10.552 -18.139 5.588   1.00 22.01  ? 170 VAL A CG1 1 
ATOM   1236  C  CG2 . VAL A 1 191 ? -12.291 -18.088 3.736   1.00 20.63  ? 170 VAL A CG2 1 
ATOM   1237  N  N   . GLY A 1 192 ? -9.493  -14.560 4.983   1.00 23.81  ? 171 GLY A N   1 
ATOM   1238  C  CA  . GLY A 1 192 ? -8.518  -13.780 5.730   1.00 25.16  ? 171 GLY A CA  1 
ATOM   1239  C  C   . GLY A 1 192 ? -9.160  -12.681 6.562   1.00 27.37  ? 171 GLY A C   1 
ATOM   1240  O  O   . GLY A 1 192 ? -8.756  -12.442 7.705   1.00 23.19  ? 171 GLY A O   1 
ATOM   1241  N  N   . ARG A 1 193 ? -10.204 -12.029 6.027   1.00 22.48  ? 172 ARG A N   1 
ATOM   1242  C  CA  . ARG A 1 193 ? -10.887 -11.012 6.828   1.00 22.26  ? 172 ARG A CA  1 
ATOM   1243  C  C   . ARG A 1 193 ? -11.526 -11.638 8.058   1.00 22.72  ? 172 ARG A C   1 
ATOM   1244  O  O   . ARG A 1 193 ? -11.544 -11.038 9.137   1.00 21.71  ? 172 ARG A O   1 
ATOM   1245  C  CB  . ARG A 1 193 ? -11.972 -10.287 6.030   1.00 25.35  ? 172 ARG A CB  1 
ATOM   1246  C  CG  . ARG A 1 193 ? -11.445 -9.387  4.910   1.00 22.90  ? 172 ARG A CG  1 
ATOM   1247  C  CD  . ARG A 1 193 ? -12.556 -8.544  4.323   1.00 27.78  ? 172 ARG A CD  1 
ATOM   1248  N  NE  . ARG A 1 193 ? -12.108 -7.781  3.159   1.00 31.86  ? 172 ARG A NE  1 
ATOM   1249  C  CZ  . ARG A 1 193 ? -11.441 -6.633  3.205   1.00 40.89  ? 172 ARG A CZ  1 
ATOM   1250  N  NH1 . ARG A 1 193 ? -11.025 -6.114  4.349   1.00 30.46  ? 172 ARG A NH1 1 
ATOM   1251  N  NH2 . ARG A 1 193 ? -11.187 -5.988  2.068   1.00 41.57  ? 172 ARG A NH2 1 
ATOM   1252  N  N   . MET A 1 194 ? -12.134 -12.810 7.881   1.00 24.17  ? 173 MET A N   1 
ATOM   1253  C  CA  . MET A 1 194 ? -12.722 -13.528 9.001   1.00 19.37  ? 173 MET A CA  1 
ATOM   1254  C  C   . MET A 1 194 ? -11.670 -13.868 10.056  1.00 25.13  ? 173 MET A C   1 
ATOM   1255  O  O   . MET A 1 194 ? -11.912 -13.708 11.253  1.00 20.89  ? 173 MET A O   1 
ATOM   1256  C  CB  . MET A 1 194 ? -13.405 -14.799 8.474   1.00 23.41  ? 173 MET A CB  1 
ATOM   1257  C  CG  . MET A 1 194 ? -14.751 -14.500 7.837   1.00 22.61  ? 173 MET A CG  1 
ATOM   1258  S  SD  . MET A 1 194 ? -15.507 -15.998 7.154   1.00 23.73  ? 173 MET A SD  1 
ATOM   1259  C  CE  . MET A 1 194 ? -17.024 -15.239 6.508   1.00 29.26  ? 173 MET A CE  1 
ATOM   1260  N  N   . ILE A 1 195 ? -10.504 -14.351 9.637   1.00 22.99  ? 174 ILE A N   1 
ATOM   1261  C  CA  . ILE A 1 195 ? -9.440  -14.621 10.615  1.00 20.28  ? 174 ILE A CA  1 
ATOM   1262  C  C   . ILE A 1 195 ? -9.066  -13.338 11.359  1.00 22.36  ? 174 ILE A C   1 
ATOM   1263  O  O   . ILE A 1 195 ? -8.964  -13.311 12.594  1.00 21.64  ? 174 ILE A O   1 
ATOM   1264  C  CB  . ILE A 1 195 ? -8.229  -15.252 9.906   1.00 16.96  ? 174 ILE A CB  1 
ATOM   1265  C  CG1 . ILE A 1 195 ? -8.610  -16.611 9.355   1.00 20.85  ? 174 ILE A CG1 1 
ATOM   1266  C  CG2 . ILE A 1 195 ? -7.036  -15.405 10.859  1.00 24.60  ? 174 ILE A CG2 1 
ATOM   1267  C  CD1 . ILE A 1 195 ? -7.559  -17.244 8.449   1.00 19.33  ? 174 ILE A CD1 1 
ATOM   1268  N  N   . THR A 1 196 ? -8.878  -12.239 10.624  1.00 23.08  ? 175 THR A N   1 
ATOM   1269  C  CA  . THR A 1 196 ? -8.499  -10.976 11.281  1.00 22.56  ? 175 THR A CA  1 
ATOM   1270  C  C   . THR A 1 196 ? -9.552  -10.539 12.288  1.00 20.36  ? 175 THR A C   1 
ATOM   1271  O  O   . THR A 1 196 ? -9.230  -10.105 13.402  1.00 23.29  ? 175 THR A O   1 
ATOM   1272  C  CB  . THR A 1 196 ? -8.266  -9.888  10.228  1.00 22.51  ? 175 THR A CB  1 
ATOM   1273  O  OG1 . THR A 1 196 ? -7.163  -10.296 9.420   1.00 22.80  ? 175 THR A OG1 1 
ATOM   1274  C  CG2 . THR A 1 196 ? -7.957  -8.496  10.892  1.00 25.45  ? 175 THR A CG2 1 
ATOM   1275  N  N   . LEU A 1 197 ? -10.828 -10.681 11.932  1.00 22.66  ? 176 LEU A N   1 
ATOM   1276  C  CA  . LEU A 1 197 ? -11.908 -10.364 12.862  1.00 17.69  ? 176 LEU A CA  1 
ATOM   1277  C  C   . LEU A 1 197 ? -11.829 -11.237 14.123  1.00 24.22  ? 176 LEU A C   1 
ATOM   1278  O  O   . LEU A 1 197 ? -11.844 -10.723 15.257  1.00 21.33  ? 176 LEU A O   1 
ATOM   1279  C  CB  . LEU A 1 197 ? -13.248 -10.564 12.126  1.00 18.17  ? 176 LEU A CB  1 
ATOM   1280  C  CG  . LEU A 1 197 ? -14.535 -10.119 12.797  1.00 24.12  ? 176 LEU A CG  1 
ATOM   1281  C  CD1 . LEU A 1 197 ? -15.660 -10.140 11.724  1.00 29.60  ? 176 LEU A CD1 1 
ATOM   1282  C  CD2 . LEU A 1 197 ? -14.965 -10.987 13.983  1.00 25.02  ? 176 LEU A CD2 1 
ATOM   1283  N  N   . LEU A 1 198 ? -11.751 -12.574 13.935  1.00 19.76  ? 177 LEU A N   1 
ATOM   1284  C  CA  . LEU A 1 198 ? -11.699 -13.519 15.054  1.00 21.66  ? 177 LEU A CA  1 
ATOM   1285  C  C   . LEU A 1 198 ? -10.491 -13.262 15.962  1.00 20.77  ? 177 LEU A C   1 
ATOM   1286  O  O   . LEU A 1 198 ? -10.551 -13.484 17.174  1.00 22.16  ? 177 LEU A O   1 
ATOM   1287  C  CB  . LEU A 1 198 ? -11.619 -14.943 14.507  1.00 19.83  ? 177 LEU A CB  1 
ATOM   1288  C  CG  . LEU A 1 198 ? -12.952 -15.431 13.925  1.00 19.44  ? 177 LEU A CG  1 
ATOM   1289  C  CD1 . LEU A 1 198 ? -12.683 -16.712 13.084  1.00 21.42  ? 177 LEU A CD1 1 
ATOM   1290  C  CD2 . LEU A 1 198 ? -13.988 -15.691 15.053  1.00 20.69  ? 177 LEU A CD2 1 
ATOM   1291  N  N   . ASP A 1 199 ? -9.380  -12.864 15.375  1.00 21.05  ? 178 ASP A N   1 
ATOM   1292  C  CA  . ASP A 1 199 ? -8.132  -12.636 16.104  1.00 24.57  ? 178 ASP A CA  1 
ATOM   1293  C  C   . ASP A 1 199 ? -8.097  -11.294 16.830  1.00 26.89  ? 178 ASP A C   1 
ATOM   1294  O  O   . ASP A 1 199 ? -7.147  -11.051 17.584  1.00 24.37  ? 178 ASP A O   1 
ATOM   1295  C  CB  . ASP A 1 199 ? -6.965  -12.704 15.126  1.00 23.87  ? 178 ASP A CB  1 
ATOM   1296  C  CG  . ASP A 1 199 ? -5.751  -13.456 15.680  1.00 37.16  ? 178 ASP A CG  1 
ATOM   1297  O  OD1 . ASP A 1 199 ? -5.869  -14.175 16.698  1.00 28.24  ? 178 ASP A OD1 1 
ATOM   1298  O  OD2 . ASP A 1 199 ? -4.671  -13.329 15.064  1.00 32.95  ? 178 ASP A OD2 1 
ATOM   1299  N  N   . ASN A 1 200 ? -9.094  -10.421 16.648  1.00 24.42  ? 179 ASN A N   1 
ATOM   1300  C  CA  . ASN A 1 200 ? -9.006  -9.053  17.197  1.00 19.00  ? 179 ASN A CA  1 
ATOM   1301  C  C   . ASN A 1 200 ? -10.212 -8.531  17.965  1.00 25.31  ? 179 ASN A C   1 
ATOM   1302  O  O   . ASN A 1 200 ? -10.071 -7.504  18.647  1.00 24.21  ? 179 ASN A O   1 
ATOM   1303  C  CB  . ASN A 1 200 ? -8.700  -8.055  16.068  1.00 21.25  ? 179 ASN A CB  1 
ATOM   1304  C  CG  . ASN A 1 200 ? -7.276  -8.129  15.629  1.00 31.05  ? 179 ASN A CG  1 
ATOM   1305  O  OD1 . ASN A 1 200 ? -6.382  -7.702  16.361  1.00 28.98  ? 179 ASN A OD1 1 
ATOM   1306  N  ND2 . ASN A 1 200 ? -7.032  -8.729  14.462  1.00 27.11  ? 179 ASN A ND2 1 
ATOM   1307  N  N   . PHE A 1 201 ? -11.367 -9.202  17.940  1.00 23.63  ? 180 PHE A N   1 
ATOM   1308  C  CA  . PHE A 1 201 ? -12.584 -8.584  18.481  1.00 21.68  ? 180 PHE A CA  1 
ATOM   1309  C  C   . PHE A 1 201 ? -12.574 -8.462  20.007  1.00 23.28  ? 180 PHE A C   1 
ATOM   1310  O  O   . PHE A 1 201 ? -13.405 -7.735  20.563  1.00 28.09  ? 180 PHE A O   1 
ATOM   1311  C  CB  . PHE A 1 201 ? -13.822 -9.391  18.094  1.00 18.07  ? 180 PHE A CB  1 
ATOM   1312  C  CG  . PHE A 1 201 ? -13.935 -10.705 18.845  1.00 21.80  ? 180 PHE A CG  1 
ATOM   1313  C  CD1 . PHE A 1 201 ? -13.259 -11.830 18.397  1.00 21.65  ? 180 PHE A CD1 1 
ATOM   1314  C  CD2 . PHE A 1 201 ? -14.750 -10.807 19.959  1.00 19.05  ? 180 PHE A CD2 1 
ATOM   1315  C  CE1 . PHE A 1 201 ? -13.359 -13.057 19.097  1.00 19.96  ? 180 PHE A CE1 1 
ATOM   1316  C  CE2 . PHE A 1 201 ? -14.851 -12.017 20.679  1.00 24.99  ? 180 PHE A CE2 1 
ATOM   1317  C  CZ  . PHE A 1 201 ? -14.158 -13.131 20.236  1.00 25.86  ? 180 PHE A CZ  1 
ATOM   1318  N  N   . GLY A 1 202 ? -11.698 -9.172  20.699  1.00 25.08  ? 181 GLY A N   1 
ATOM   1319  C  CA  . GLY A 1 202 ? -11.829 -9.243  22.142  1.00 23.02  ? 181 GLY A CA  1 
ATOM   1320  C  C   . GLY A 1 202 ? -10.885 -8.345  22.933  1.00 25.14  ? 181 GLY A C   1 
ATOM   1321  O  O   . GLY A 1 202 ? -10.851 -8.462  24.160  1.00 26.88  ? 181 GLY A O   1 
ATOM   1322  N  N   . THR A 1 203 ? -10.092 -7.498  22.280  1.00 25.37  ? 182 THR A N   1 
ATOM   1323  C  CA  . THR A 1 203 ? -9.136  -6.624  22.960  1.00 26.74  ? 182 THR A CA  1 
ATOM   1324  C  C   . THR A 1 203 ? -9.393  -5.152  22.614  1.00 33.57  ? 182 THR A C   1 
ATOM   1325  O  O   . THR A 1 203 ? -9.963  -4.823  21.568  1.00 28.84  ? 182 THR A O   1 
ATOM   1326  C  CB  . THR A 1 203 ? -7.675  -6.956  22.592  1.00 30.70  ? 182 THR A CB  1 
ATOM   1327  O  OG1 . THR A 1 203 ? -7.415  -6.568  21.235  1.00 32.25  ? 182 THR A OG1 1 
ATOM   1328  C  CG2 . THR A 1 203 ? -7.348  -8.456  22.780  1.00 28.02  ? 182 THR A CG2 1 
ATOM   1329  N  N   . ALA A 1 204 ? -8.933  -4.259  23.506  1.00 34.50  ? 183 ALA A N   1 
ATOM   1330  C  CA  . ALA A 1 204 ? -9.017  -2.817  23.247  1.00 34.61  ? 183 ALA A CA  1 
ATOM   1331  C  C   . ALA A 1 204 ? -8.287  -2.419  21.961  1.00 28.10  ? 183 ALA A C   1 
ATOM   1332  O  O   . ALA A 1 204 ? -8.815  -1.641  21.156  1.00 33.19  ? 183 ALA A O   1 
ATOM   1333  C  CB  . ALA A 1 204 ? -8.466  -2.029  24.449  1.00 33.28  ? 183 ALA A CB  1 
ATOM   1334  N  N   . THR A 1 205 ? -7.079  -2.935  21.744  1.00 27.63  ? 184 THR A N   1 
ATOM   1335  C  CA  . THR A 1 205 ? -6.328  -2.585  20.538  1.00 32.79  ? 184 THR A CA  1 
ATOM   1336  C  C   . THR A 1 205 ? -6.969  -3.180  19.294  1.00 33.38  ? 184 THR A C   1 
ATOM   1337  O  O   . THR A 1 205 ? -6.883  -2.599  18.206  1.00 29.90  ? 184 THR A O   1 
ATOM   1338  C  CB  . THR A 1 205 ? -4.880  -3.080  20.663  1.00 39.81  ? 184 THR A CB  1 
ATOM   1339  O  OG1 . THR A 1 205 ? -4.281  -2.502  21.830  1.00 51.89  ? 184 THR A OG1 1 
ATOM   1340  C  CG2 . THR A 1 205 ? -4.044  -2.691  19.439  1.00 41.22  ? 184 THR A CG2 1 
ATOM   1341  N  N   . GLY A 1 206 ? -7.604  -4.340  19.430  1.00 27.36  ? 185 GLY A N   1 
ATOM   1342  C  CA  . GLY A 1 206 ? -8.068  -5.052  18.256  1.00 23.97  ? 185 GLY A CA  1 
ATOM   1343  C  C   . GLY A 1 206 ? -9.457  -4.642  17.788  1.00 25.42  ? 185 GLY A C   1 
ATOM   1344  O  O   . GLY A 1 206 ? -9.776  -4.811  16.608  1.00 27.64  ? 185 GLY A O   1 
ATOM   1345  N  N   . THR A 1 207 ? -10.299 -4.125  18.685  1.00 23.81  ? 186 THR A N   1 
ATOM   1346  C  CA  . THR A 1 207 ? -11.699 -3.953  18.308  1.00 26.82  ? 186 THR A CA  1 
ATOM   1347  C  C   . THR A 1 207 ? -11.898 -3.020  17.104  1.00 29.64  ? 186 THR A C   1 
ATOM   1348  O  O   . THR A 1 207 ? -12.773 -3.332  16.274  1.00 27.55  ? 186 THR A O   1 
ATOM   1349  C  CB  . THR A 1 207 ? -12.532 -3.534  19.532  1.00 28.12  ? 186 THR A CB  1 
ATOM   1350  O  OG1 . THR A 1 207 ? -13.905 -3.380  19.149  1.00 32.51  ? 186 THR A OG1 1 
ATOM   1351  C  CG2 . THR A 1 207 ? -12.057 -2.257  20.191  1.00 32.60  ? 186 THR A CG2 1 
ATOM   1352  N  N   . PRO A 1 208 ? -11.111 -1.957  16.880  1.00 29.61  ? 187 PRO A N   1 
ATOM   1353  C  CA  . PRO A 1 208 ? -11.333 -1.195  15.634  1.00 26.85  ? 187 PRO A CA  1 
ATOM   1354  C  C   . PRO A 1 208 ? -11.027 -2.006  14.399  1.00 30.22  ? 187 PRO A C   1 
ATOM   1355  O  O   . PRO A 1 208 ? -11.747 -1.875  13.392  1.00 24.89  ? 187 PRO A O   1 
ATOM   1356  C  CB  . PRO A 1 208 ? -10.409 0.027   15.790  1.00 29.28  ? 187 PRO A CB  1 
ATOM   1357  C  CG  . PRO A 1 208 ? -9.369  -0.407  16.749  1.00 44.03  ? 187 PRO A CG  1 
ATOM   1358  C  CD  . PRO A 1 208 ? -10.058 -1.321  17.702  1.00 33.36  ? 187 PRO A CD  1 
ATOM   1359  N  N   . LYS A 1 209 ? -9.998  -2.868  14.451  1.00 24.36  ? 188 LYS A N   1 
ATOM   1360  C  CA  . LYS A 1 209 ? -9.720  -3.752  13.322  1.00 25.87  ? 188 LYS A CA  1 
ATOM   1361  C  C   . LYS A 1 209 ? -10.868 -4.739  13.100  1.00 27.53  ? 188 LYS A C   1 
ATOM   1362  O  O   . LYS A 1 209 ? -11.235 -5.030  11.955  1.00 23.41  ? 188 LYS A O   1 
ATOM   1363  C  CB  . LYS A 1 209 ? -8.421  -4.532  13.541  1.00 30.30  ? 188 LYS A CB  1 
ATOM   1364  C  CG  . LYS A 1 209 ? -7.244  -3.683  14.019  1.00 34.15  ? 188 LYS A CG  1 
ATOM   1365  C  CD  . LYS A 1 209 ? -6.000  -4.539  14.160  1.00 43.77  ? 188 LYS A CD  1 
ATOM   1366  C  CE  . LYS A 1 209 ? -4.934  -3.802  14.936  1.00 53.12  ? 188 LYS A CE  1 
ATOM   1367  N  NZ  . LYS A 1 209 ? -3.649  -4.544  14.859  1.00 69.81  ? 188 LYS A NZ  1 
ATOM   1368  N  N   . ALA A 1 210 ? -11.412 -5.296  14.176  1.00 22.32  ? 189 ALA A N   1 
ATOM   1369  C  CA  . ALA A 1 210 ? -12.523 -6.229  14.034  1.00 25.26  ? 189 ALA A CA  1 
ATOM   1370  C  C   . ALA A 1 210 ? -13.732 -5.542  13.417  1.00 26.54  ? 189 ALA A C   1 
ATOM   1371  O  O   . ALA A 1 210 ? -14.401 -6.101  12.535  1.00 21.99  ? 189 ALA A O   1 
ATOM   1372  C  CB  . ALA A 1 210 ? -12.904 -6.821  15.390  1.00 24.37  ? 189 ALA A CB  1 
ATOM   1373  N  N   . PHE A 1 211 ? -14.051 -4.338  13.894  1.00 21.38  ? 190 PHE A N   1 
ATOM   1374  C  CA  . PHE A 1 211 ? -15.222 -3.664  13.348  1.00 24.09  ? 190 PHE A CA  1 
ATOM   1375  C  C   . PHE A 1 211 ? -15.002 -3.257  11.897  1.00 25.94  ? 190 PHE A C   1 
ATOM   1376  O  O   . PHE A 1 211 ? -15.947 -3.284  11.098  1.00 24.95  ? 190 PHE A O   1 
ATOM   1377  C  CB  . PHE A 1 211 ? -15.589 -2.468  14.227  1.00 26.68  ? 190 PHE A CB  1 
ATOM   1378  C  CG  . PHE A 1 211 ? -16.551 -2.819  15.326  1.00 23.06  ? 190 PHE A CG  1 
ATOM   1379  C  CD1 . PHE A 1 211 ? -17.883 -3.041  15.033  1.00 24.72  ? 190 PHE A CD1 1 
ATOM   1380  C  CD2 . PHE A 1 211 ? -16.116 -2.972  16.639  1.00 23.45  ? 190 PHE A CD2 1 
ATOM   1381  C  CE1 . PHE A 1 211 ? -18.783 -3.385  16.032  1.00 28.31  ? 190 PHE A CE1 1 
ATOM   1382  C  CE2 . PHE A 1 211 ? -17.009 -3.327  17.652  1.00 24.87  ? 190 PHE A CE2 1 
ATOM   1383  C  CZ  . PHE A 1 211 ? -18.347 -3.526  17.339  1.00 27.79  ? 190 PHE A CZ  1 
ATOM   1384  N  N   . TRP A 1 212 ? -13.765 -2.936  11.517  1.00 24.06  ? 191 TRP A N   1 
ATOM   1385  C  CA  . TRP A 1 212 ? -13.494 -2.656  10.109  1.00 27.33  ? 191 TRP A CA  1 
ATOM   1386  C  C   . TRP A 1 212 ? -13.772 -3.890  9.254   1.00 31.24  ? 191 TRP A C   1 
ATOM   1387  O  O   . TRP A 1 212 ? -14.386 -3.792  8.185   1.00 25.79  ? 191 TRP A O   1 
ATOM   1388  C  CB  . TRP A 1 212 ? -12.045 -2.184  9.915   1.00 28.46  ? 191 TRP A CB  1 
ATOM   1389  C  CG  . TRP A 1 212 ? -11.688 -2.010  8.474   1.00 34.30  ? 191 TRP A CG  1 
ATOM   1390  C  CD1 . TRP A 1 212 ? -10.904 -2.836  7.709   1.00 32.13  ? 191 TRP A CD1 1 
ATOM   1391  C  CD2 . TRP A 1 212 ? -12.135 -0.971  7.599   1.00 34.51  ? 191 TRP A CD2 1 
ATOM   1392  N  NE1 . TRP A 1 212 ? -10.829 -2.361  6.434   1.00 31.57  ? 191 TRP A NE1 1 
ATOM   1393  C  CE2 . TRP A 1 212 ? -11.580 -1.222  6.334   1.00 38.47  ? 191 TRP A CE2 1 
ATOM   1394  C  CE3 . TRP A 1 212 ? -12.962 0.141   7.763   1.00 49.36  ? 191 TRP A CE3 1 
ATOM   1395  C  CZ2 . TRP A 1 212 ? -11.813 -0.398  5.239   1.00 44.94  ? 191 TRP A CZ2 1 
ATOM   1396  C  CZ3 . TRP A 1 212 ? -13.190 0.961   6.675   1.00 56.84  ? 191 TRP A CZ3 1 
ATOM   1397  C  CH2 . TRP A 1 212 ? -12.614 0.688   5.433   1.00 46.44  ? 191 TRP A CH2 1 
ATOM   1398  N  N   . GLN A 1 213 ? -13.293 -5.061  9.697   1.00 24.08  ? 192 GLN A N   1 
ATOM   1399  C  CA  . GLN A 1 213 ? -13.511 -6.274  8.913   1.00 25.86  ? 192 GLN A CA  1 
ATOM   1400  C  C   . GLN A 1 213 ? -14.992 -6.649  8.862   1.00 23.75  ? 192 GLN A C   1 
ATOM   1401  O  O   . GLN A 1 213 ? -15.489 -7.097  7.819   1.00 24.53  ? 192 GLN A O   1 
ATOM   1402  C  CB  . GLN A 1 213 ? -12.682 -7.433  9.483   1.00 26.24  ? 192 GLN A CB  1 
ATOM   1403  C  CG  . GLN A 1 213 ? -11.160 -7.222  9.445   1.00 26.40  ? 192 GLN A CG  1 
ATOM   1404  C  CD  . GLN A 1 213 ? -10.617 -6.962  8.051   1.00 28.44  ? 192 GLN A CD  1 
ATOM   1405  O  OE1 . GLN A 1 213 ? -11.217 -7.339  7.040   1.00 32.37  ? 192 GLN A OE1 1 
ATOM   1406  N  NE2 . GLN A 1 213 ? -9.495  -6.269  7.985   1.00 27.42  ? 192 GLN A NE2 1 
ATOM   1407  N  N   . ARG A 1 214 ? -15.700 -6.492  9.984   1.00 22.73  ? 193 ARG A N   1 
ATOM   1408  C  CA  . ARG A 1 214 ? -17.136 -6.756  10.026  1.00 20.74  ? 193 ARG A CA  1 
ATOM   1409  C  C   . ARG A 1 214 ? -17.870 -5.914  8.989   1.00 27.28  ? 193 ARG A C   1 
ATOM   1410  O  O   . ARG A 1 214 ? -18.735 -6.420  8.260   1.00 22.28  ? 193 ARG A O   1 
ATOM   1411  C  CB  . ARG A 1 214 ? -17.641 -6.483  11.446  1.00 24.05  ? 193 ARG A CB  1 
ATOM   1412  C  CG  . ARG A 1 214 ? -19.144 -6.292  11.662  1.00 25.71  ? 193 ARG A CG  1 
ATOM   1413  C  CD  . ARG A 1 214 ? -19.937 -7.519  11.220  1.00 25.16  ? 193 ARG A CD  1 
ATOM   1414  N  NE  . ARG A 1 214 ? -19.462 -8.759  11.825  1.00 25.57  ? 193 ARG A NE  1 
ATOM   1415  C  CZ  . ARG A 1 214 ? -20.017 -9.944  11.595  1.00 24.73  ? 193 ARG A CZ  1 
ATOM   1416  N  NH1 . ARG A 1 214 ? -21.014 -10.087 10.733  1.00 25.02  ? 193 ARG A NH1 1 
ATOM   1417  N  NH2 . ARG A 1 214 ? -19.582 -11.002 12.260  1.00 21.87  ? 193 ARG A NH2 1 
ATOM   1418  N  N   . ARG A 1 215 ? -17.510 -4.633  8.878   1.00 25.13  ? 194 ARG A N   1 
ATOM   1419  C  CA  . ARG A 1 215 ? -18.152 -3.778  7.886   1.00 30.71  ? 194 ARG A CA  1 
ATOM   1420  C  C   . ARG A 1 215 ? -17.941 -4.313  6.474   1.00 23.35  ? 194 ARG A C   1 
ATOM   1421  O  O   . ARG A 1 215 ? -18.897 -4.461  5.709   1.00 27.62  ? 194 ARG A O   1 
ATOM   1422  C  CB  . ARG A 1 215 ? -17.622 -2.344  7.991   1.00 28.74  ? 194 ARG A CB  1 
ATOM   1423  C  CG  . ARG A 1 215 ? -18.300 -1.397  7.030   1.00 42.12  ? 194 ARG A CG  1 
ATOM   1424  C  CD  . ARG A 1 215 ? -19.762 -1.294  7.382   1.00 51.35  ? 194 ARG A CD  1 
ATOM   1425  N  NE  . ARG A 1 215 ? -19.971 -0.436  8.541   1.00 68.33  ? 194 ARG A NE  1 
ATOM   1426  C  CZ  . ARG A 1 215 ? -20.682 0.683   8.519   1.00 73.01  ? 194 ARG A CZ  1 
ATOM   1427  N  NH1 . ARG A 1 215 ? -21.307 1.083   7.421   1.00 80.83  ? 194 ARG A NH1 1 
ATOM   1428  N  NH2 . ARG A 1 215 ? -20.779 1.412   9.629   1.00 79.86  ? 194 ARG A NH2 1 
ATOM   1429  N  N   . GLN A 1 216 ? -16.689 -4.596  6.106   1.00 22.64  ? 195 GLN A N   1 
ATOM   1430  C  CA  . GLN A 1 216 ? -16.418 -5.110  4.769   1.00 26.50  ? 195 GLN A CA  1 
ATOM   1431  C  C   . GLN A 1 216 ? -17.118 -6.444  4.508   1.00 25.66  ? 195 GLN A C   1 
ATOM   1432  O  O   . GLN A 1 216 ? -17.604 -6.680  3.399   1.00 25.56  ? 195 GLN A O   1 
ATOM   1433  C  CB  . GLN A 1 216 ? -14.922 -5.285  4.566   1.00 25.47  ? 195 GLN A CB  1 
ATOM   1434  C  CG  . GLN A 1 216 ? -14.094 -4.029  4.861   1.00 27.63  ? 195 GLN A CG  1 
ATOM   1435  C  CD  . GLN A 1 216 ? -14.724 -2.812  4.276   1.00 41.39  ? 195 GLN A CD  1 
ATOM   1436  O  OE1 . GLN A 1 216 ? -14.935 -2.743  3.075   1.00 39.50  ? 195 GLN A OE1 1 
ATOM   1437  N  NE2 . GLN A 1 216 ? -15.081 -1.856  5.128   1.00 44.20  ? 195 GLN A NE2 1 
ATOM   1438  N  N   . LEU A 1 217 ? -17.084 -7.371  5.478   1.00 20.33  ? 196 LEU A N   1 
ATOM   1439  C  CA  . LEU A 1 217 ? -17.731 -8.664  5.286   1.00 22.68  ? 196 LEU A CA  1 
ATOM   1440  C  C   . LEU A 1 217 ? -19.244 -8.520  5.153   1.00 25.36  ? 196 LEU A C   1 
ATOM   1441  O  O   . LEU A 1 217 ? -19.861 -9.208  4.328   1.00 22.78  ? 196 LEU A O   1 
ATOM   1442  C  CB  . LEU A 1 217 ? -17.384 -9.597  6.464   1.00 25.19  ? 196 LEU A CB  1 
ATOM   1443  C  CG  . LEU A 1 217 ? -15.917 -10.054 6.498   1.00 23.41  ? 196 LEU A CG  1 
ATOM   1444  C  CD1 . LEU A 1 217 ? -15.485 -10.589 7.887   1.00 24.94  ? 196 LEU A CD1 1 
ATOM   1445  C  CD2 . LEU A 1 217 ? -15.790 -11.166 5.418   1.00 24.62  ? 196 LEU A CD2 1 
ATOM   1446  N  N   . ASP A 1 218 ? -19.872 -7.686  5.998   1.00 21.31  ? 197 ASP A N   1 
ATOM   1447  C  CA  . ASP A 1 218 ? -21.315 -7.470  5.871   1.00 25.71  ? 197 ASP A CA  1 
ATOM   1448  C  C   . ASP A 1 218 ? -21.683 -6.875  4.511   1.00 21.57  ? 197 ASP A C   1 
ATOM   1449  O  O   . ASP A 1 218 ? -22.704 -7.255  3.930   1.00 24.77  ? 197 ASP A O   1 
ATOM   1450  C  CB  . ASP A 1 218 ? -21.841 -6.546  6.967   1.00 25.21  ? 197 ASP A CB  1 
ATOM   1451  C  CG  . ASP A 1 218 ? -21.868 -7.193  8.361   1.00 35.68  ? 197 ASP A CG  1 
ATOM   1452  O  OD1 . ASP A 1 218 ? -21.615 -8.413  8.505   1.00 32.28  ? 197 ASP A OD1 1 
ATOM   1453  O  OD2 . ASP A 1 218 ? -22.158 -6.453  9.332   1.00 33.44  ? 197 ASP A OD2 1 
ATOM   1454  N  N   . ASN A 1 219 ? -20.907 -5.893  4.016   1.00 25.25  ? 198 ASN A N   1 
ATOM   1455  C  CA  . ASN A 1 219 ? -21.176 -5.356  2.678   1.00 29.12  ? 198 ASN A CA  1 
ATOM   1456  C  C   . ASN A 1 219 ? -21.069 -6.448  1.621   1.00 29.92  ? 198 ASN A C   1 
ATOM   1457  O  O   . ASN A 1 219 ? -21.911 -6.549  0.716   1.00 23.83  ? 198 ASN A O   1 
ATOM   1458  C  CB  . ASN A 1 219 ? -20.198 -4.221  2.330   1.00 25.08  ? 198 ASN A CB  1 
ATOM   1459  C  CG  . ASN A 1 219 ? -20.372 -2.988  3.198   1.00 32.15  ? 198 ASN A CG  1 
ATOM   1460  O  OD1 . ASN A 1 219 ? -21.391 -2.799  3.855   1.00 29.24  ? 198 ASN A OD1 1 
ATOM   1461  N  ND2 . ASN A 1 219 ? -19.370 -2.109  3.164   1.00 29.96  ? 198 ASN A ND2 1 
ATOM   1462  N  N   . TRP A 1 220 ? -20.024 -7.270  1.715   1.00 25.30  ? 199 TRP A N   1 
ATOM   1463  C  CA  . TRP A 1 220 ? -19.841 -8.364  0.765   1.00 25.81  ? 199 TRP A CA  1 
ATOM   1464  C  C   . TRP A 1 220 ? -21.006 -9.347  0.817   1.00 24.09  ? 199 TRP A C   1 
ATOM   1465  O  O   . TRP A 1 220 ? -21.574 -9.696  -0.219  1.00 27.35  ? 199 TRP A O   1 
ATOM   1466  C  CB  . TRP A 1 220 ? -18.527 -9.092  1.033   1.00 24.95  ? 199 TRP A CB  1 
ATOM   1467  C  CG  . TRP A 1 220 ? -18.558 -10.499 0.429   1.00 26.77  ? 199 TRP A CG  1 
ATOM   1468  C  CD1 . TRP A 1 220 ? -18.422 -10.833 -0.900  1.00 30.39  ? 199 TRP A CD1 1 
ATOM   1469  C  CD2 . TRP A 1 220 ? -18.762 -11.730 1.131   1.00 28.14  ? 199 TRP A CD2 1 
ATOM   1470  N  NE1 . TRP A 1 220 ? -18.535 -12.206 -1.058  1.00 30.07  ? 199 TRP A NE1 1 
ATOM   1471  C  CE2 . TRP A 1 220 ? -18.748 -12.776 0.168   1.00 27.40  ? 199 TRP A CE2 1 
ATOM   1472  C  CE3 . TRP A 1 220 ? -18.937 -12.056 2.474   1.00 25.09  ? 199 TRP A CE3 1 
ATOM   1473  C  CZ2 . TRP A 1 220 ? -18.901 -14.122 0.517   1.00 26.58  ? 199 TRP A CZ2 1 
ATOM   1474  C  CZ3 . TRP A 1 220 ? -19.096 -13.394 2.821   1.00 29.47  ? 199 TRP A CZ3 1 
ATOM   1475  C  CH2 . TRP A 1 220 ? -19.084 -14.409 1.835   1.00 27.78  ? 199 TRP A CH2 1 
ATOM   1476  N  N   . ALA A 1 221 ? -21.384 -9.795  2.017   1.00 22.69  ? 200 ALA A N   1 
ATOM   1477  C  CA  . ALA A 1 221 ? -22.429 -10.807 2.142   1.00 24.93  ? 200 ALA A CA  1 
ATOM   1478  C  C   . ALA A 1 221 ? -23.801 -10.263 1.738   1.00 24.59  ? 200 ALA A C   1 
ATOM   1479  O  O   . ALA A 1 221 ? -24.632 -11.012 1.202   1.00 26.25  ? 200 ALA A O   1 
ATOM   1480  C  CB  . ALA A 1 221 ? -22.500 -11.329 3.572   1.00 22.12  ? 200 ALA A CB  1 
ATOM   1481  N  N   . GLU A 1 222 ? -24.077 -8.993  2.054   1.00 21.09  ? 201 GLU A N   1 
ATOM   1482  C  CA  . GLU A 1 222 ? -25.331 -8.380  1.618   1.00 26.65  ? 201 GLU A CA  1 
ATOM   1483  C  C   . GLU A 1 222 ? -25.410 -8.349  0.100   1.00 27.64  ? 201 GLU A C   1 
ATOM   1484  O  O   . GLU A 1 222 ? -26.450 -8.678  -0.490  1.00 29.04  ? 201 GLU A O   1 
ATOM   1485  C  CB  . GLU A 1 222 ? -25.465 -6.953  2.158   1.00 23.33  ? 201 GLU A CB  1 
ATOM   1486  C  CG  . GLU A 1 222 ? -26.843 -6.343  1.825   1.00 27.16  ? 201 GLU A CG  1 
ATOM   1487  C  CD  . GLU A 1 222 ? -27.016 -4.896  2.261   1.00 39.79  ? 201 GLU A CD  1 
ATOM   1488  O  OE1 . GLU A 1 222 ? -26.190 -4.375  3.040   1.00 34.10  ? 201 GLU A OE1 1 
ATOM   1489  O  OE2 . GLU A 1 222 ? -28.001 -4.265  1.813   1.00 42.20  ? 201 GLU A OE2 1 
ATOM   1490  N  N   . ALA A 1 223 ? -24.316 -7.936  -0.548  1.00 26.27  ? 202 ALA A N   1 
ATOM   1491  C  CA  . ALA A 1 223 ? -24.294 -7.888  -2.006  1.00 29.17  ? 202 ALA A CA  1 
ATOM   1492  C  C   . ALA A 1 223 ? -24.496 -9.269  -2.616  1.00 30.95  ? 202 ALA A C   1 
ATOM   1493  O  O   . ALA A 1 223 ? -25.158 -9.391  -3.650  1.00 26.36  ? 202 ALA A O   1 
ATOM   1494  C  CB  . ALA A 1 223 ? -22.983 -7.294  -2.505  1.00 25.74  ? 202 ALA A CB  1 
ATOM   1495  N  N   . LEU A 1 224 ? -23.885 -10.311 -2.020  1.00 23.88  ? 203 LEU A N   1 
ATOM   1496  C  CA  . LEU A 1 224 ? -24.068 -11.680 -2.504  1.00 23.98  ? 203 LEU A CA  1 
ATOM   1497  C  C   . LEU A 1 224 ? -25.508 -12.156 -2.334  1.00 24.42  ? 203 LEU A C   1 
ATOM   1498  O  O   . LEU A 1 224 ? -26.087 -12.734 -3.264  1.00 25.73  ? 203 LEU A O   1 
ATOM   1499  C  CB  . LEU A 1 224 ? -23.111 -12.630 -1.785  1.00 24.92  ? 203 LEU A CB  1 
ATOM   1500  C  CG  . LEU A 1 224 ? -23.222 -14.108 -2.159  1.00 27.10  ? 203 LEU A CG  1 
ATOM   1501  C  CD1 . LEU A 1 224 ? -22.999 -14.326 -3.650  1.00 31.71  ? 203 LEU A CD1 1 
ATOM   1502  C  CD2 . LEU A 1 224 ? -22.231 -14.951 -1.331  1.00 30.55  ? 203 LEU A CD2 1 
ATOM   1503  N  N   . ILE A 1 225 ? -26.116 -11.929 -1.155  1.00 21.86  ? 204 ILE A N   1 
ATOM   1504  C  CA  . ILE A 1 225 ? -27.519 -12.323 -0.960  1.00 20.79  ? 204 ILE A CA  1 
ATOM   1505  C  C   . ILE A 1 225 ? -28.405 -11.609 -1.968  1.00 25.23  ? 204 ILE A C   1 
ATOM   1506  O  O   . ILE A 1 225 ? -29.341 -12.194 -2.519  1.00 24.61  ? 204 ILE A O   1 
ATOM   1507  C  CB  . ILE A 1 225 ? -28.010 -12.004 0.470   1.00 19.07  ? 204 ILE A CB  1 
ATOM   1508  C  CG1 . ILE A 1 225 ? -27.326 -12.879 1.544   1.00 23.03  ? 204 ILE A CG1 1 
ATOM   1509  C  CG2 . ILE A 1 225 ? -29.502 -12.118 0.562   1.00 20.94  ? 204 ILE A CG2 1 
ATOM   1510  C  CD1 . ILE A 1 225 ? -27.592 -14.373 1.401   1.00 23.69  ? 204 ILE A CD1 1 
ATOM   1511  N  N   . THR A 1 226 ? -28.165 -10.312 -2.165  1.00 24.42  ? 205 THR A N   1 
ATOM   1512  C  CA  . THR A 1 226 ? -28.998 -9.543  -3.097  1.00 28.68  ? 205 THR A CA  1 
ATOM   1513  C  C   . THR A 1 226 ? -28.829 -10.051 -4.521  1.00 32.37  ? 205 THR A C   1 
ATOM   1514  O  O   . THR A 1 226 ? -29.813 -10.175 -5.271  1.00 29.89  ? 205 THR A O   1 
ATOM   1515  C  CB  . THR A 1 226 ? -28.646 -8.062  -2.986  1.00 31.05  ? 205 THR A CB  1 
ATOM   1516  O  OG1 . THR A 1 226 ? -28.939 -7.635  -1.661  1.00 34.68  ? 205 THR A OG1 1 
ATOM   1517  C  CG2 . THR A 1 226 ? -29.452 -7.187  -3.978  1.00 37.96  ? 205 THR A CG2 1 
ATOM   1518  N  N   . ASP A 1 227 ? -27.587 -10.374 -4.904  1.00 27.96  ? 206 ASP A N   1 
ATOM   1519  C  CA  . ASP A 1 227 ? -27.352 -10.969 -6.215  1.00 27.14  ? 206 ASP A CA  1 
ATOM   1520  C  C   . ASP A 1 227 ? -28.098 -12.285 -6.385  1.00 30.53  ? 206 ASP A C   1 
ATOM   1521  O  O   . ASP A 1 227 ? -28.576 -12.580 -7.485  1.00 29.58  ? 206 ASP A O   1 
ATOM   1522  C  CB  . ASP A 1 227 ? -25.866 -11.213 -6.458  1.00 26.02  ? 206 ASP A CB  1 
ATOM   1523  C  CG  . ASP A 1 227 ? -25.120 -9.969  -6.891  1.00 39.50  ? 206 ASP A CG  1 
ATOM   1524  O  OD1 . ASP A 1 227 ? -25.746 -8.935  -7.230  1.00 43.51  ? 206 ASP A OD1 1 
ATOM   1525  O  OD2 . ASP A 1 227 ? -23.881 -10.037 -6.881  1.00 44.10  ? 206 ASP A OD2 1 
ATOM   1526  N  N   . VAL A 1 228 ? -28.161 -13.125 -5.337  1.00 25.70  ? 207 VAL A N   1 
ATOM   1527  C  CA  . VAL A 1 228 ? -28.897 -14.373 -5.487  1.00 27.14  ? 207 VAL A CA  1 
ATOM   1528  C  C   . VAL A 1 228 ? -30.384 -14.069 -5.604  1.00 30.94  ? 207 VAL A C   1 
ATOM   1529  O  O   . VAL A 1 228 ? -31.069 -14.590 -6.493  1.00 29.65  ? 207 VAL A O   1 
ATOM   1530  C  CB  . VAL A 1 228 ? -28.599 -15.376 -4.339  1.00 23.17  ? 207 VAL A CB  1 
ATOM   1531  C  CG1 . VAL A 1 228 ? -29.476 -16.618 -4.499  1.00 22.60  ? 207 VAL A CG1 1 
ATOM   1532  C  CG2 . VAL A 1 228 ? -27.119 -15.848 -4.377  1.00 25.02  ? 207 VAL A CG2 1 
ATOM   1533  N  N   . ARG A 1 229 ? -30.892 -13.173 -4.753  1.00 26.62  ? 208 ARG A N   1 
ATOM   1534  C  CA  . ARG A 1 229 ? -32.327 -12.887 -4.764  1.00 29.13  ? 208 ARG A CA  1 
ATOM   1535  C  C   . ARG A 1 229 ? -32.770 -12.221 -6.068  1.00 30.22  ? 208 ARG A C   1 
ATOM   1536  O  O   . ARG A 1 229 ? -33.937 -12.343 -6.464  1.00 29.93  ? 208 ARG A O   1 
ATOM   1537  C  CB  . ARG A 1 229 ? -32.702 -11.998 -3.584  1.00 26.66  ? 208 ARG A CB  1 
ATOM   1538  C  CG  . ARG A 1 229 ? -32.682 -12.734 -2.248  1.00 27.06  ? 208 ARG A CG  1 
ATOM   1539  C  CD  . ARG A 1 229 ? -33.009 -11.773 -1.128  1.00 28.62  ? 208 ARG A CD  1 
ATOM   1540  N  NE  . ARG A 1 229 ? -33.112 -12.492 0.132   1.00 28.02  ? 208 ARG A NE  1 
ATOM   1541  C  CZ  . ARG A 1 229 ? -33.331 -11.921 1.304   1.00 23.09  ? 208 ARG A CZ  1 
ATOM   1542  N  NH1 . ARG A 1 229 ? -33.434 -10.608 1.425   1.00 25.01  ? 208 ARG A NH1 1 
ATOM   1543  N  NH2 . ARG A 1 229 ? -33.505 -12.695 2.376   1.00 27.16  ? 208 ARG A NH2 1 
ATOM   1544  N  N   . GLU A 1 230 ? -31.879 -11.506 -6.734  1.00 27.92  ? 209 GLU A N   1 
ATOM   1545  C  CA  . GLU A 1 230 ? -32.256 -10.828 -7.964  1.00 30.84  ? 209 GLU A CA  1 
ATOM   1546  C  C   . GLU A 1 230 ? -31.961 -11.655 -9.210  1.00 31.18  ? 209 GLU A C   1 
ATOM   1547  O  O   . GLU A 1 230 ? -32.238 -11.190 -10.314 1.00 36.18  ? 209 GLU A O   1 
ATOM   1548  C  CB  . GLU A 1 230 ? -31.565 -9.459  -8.025  1.00 33.53  ? 209 GLU A CB  1 
ATOM   1549  C  CG  . GLU A 1 230 ? -32.204 -8.477  -7.019  1.00 43.08  ? 209 GLU A CG  1 
ATOM   1550  C  CD  . GLU A 1 230 ? -31.560 -7.101  -6.985  1.00 47.66  ? 209 GLU A CD  1 
ATOM   1551  O  OE1 . GLU A 1 230 ? -30.569 -6.892  -7.714  1.00 50.72  ? 209 GLU A OE1 1 
ATOM   1552  O  OE2 . GLU A 1 230 ? -32.044 -6.228  -6.220  1.00 47.52  ? 209 GLU A OE2 1 
ATOM   1553  N  N   . GLY A 1 231 ? -31.396 -12.855 -9.070  1.00 28.79  ? 210 GLY A N   1 
ATOM   1554  C  CA  . GLY A 1 231 ? -31.094 -13.702 -10.216 1.00 32.75  ? 210 GLY A CA  1 
ATOM   1555  C  C   . GLY A 1 231 ? -29.770 -13.436 -10.902 1.00 35.50  ? 210 GLY A C   1 
ATOM   1556  O  O   . GLY A 1 231 ? -29.450 -14.115 -11.882 1.00 33.58  ? 210 GLY A O   1 
ATOM   1557  N  N   . ARG A 1 232 ? -28.973 -12.497 -10.408 1.00 32.63  ? 211 ARG A N   1 
ATOM   1558  C  CA  . ARG A 1 232 ? -27.686 -12.237 -11.032 1.00 29.60  ? 211 ARG A CA  1 
ATOM   1559  C  C   . ARG A 1 232 ? -26.680 -13.342 -10.763 1.00 32.75  ? 211 ARG A C   1 
ATOM   1560  O  O   . ARG A 1 232 ? -25.732 -13.523 -11.534 1.00 35.32  ? 211 ARG A O   1 
ATOM   1561  C  CB  . ARG A 1 232 ? -27.157 -10.897 -10.545 1.00 33.21  ? 211 ARG A CB  1 
ATOM   1562  C  CG  . ARG A 1 232 ? -27.859 -9.755  -11.240 1.00 45.22  ? 211 ARG A CG  1 
ATOM   1563  C  CD  . ARG A 1 232 ? -27.121 -8.465  -11.030 1.00 47.25  ? 211 ARG A CD  1 
ATOM   1564  N  NE  . ARG A 1 232 ? -27.064 -8.167  -9.611  1.00 50.04  ? 211 ARG A NE  1 
ATOM   1565  C  CZ  . ARG A 1 232 ? -28.055 -7.603  -8.941  1.00 54.38  ? 211 ARG A CZ  1 
ATOM   1566  N  NH1 . ARG A 1 232 ? -29.182 -7.262  -9.540  1.00 52.13  ? 211 ARG A NH1 1 
ATOM   1567  N  NH2 . ARG A 1 232 ? -27.914 -7.374  -7.637  1.00 56.05  ? 211 ARG A NH2 1 
ATOM   1568  N  N   . ILE A 1 233 ? -26.841 -14.065 -9.670  1.00 34.14  ? 212 ILE A N   1 
ATOM   1569  C  CA  . ILE A 1 233 ? -26.003 -15.205 -9.347  1.00 28.79  ? 212 ILE A CA  1 
ATOM   1570  C  C   . ILE A 1 233 ? -26.938 -16.367 -9.094  1.00 33.97  ? 212 ILE A C   1 
ATOM   1571  O  O   . ILE A 1 233 ? -27.970 -16.205 -8.435  1.00 33.80  ? 212 ILE A O   1 
ATOM   1572  C  CB  . ILE A 1 233 ? -25.121 -14.927 -8.112  1.00 37.40  ? 212 ILE A CB  1 
ATOM   1573  C  CG1 . ILE A 1 233 ? -24.047 -13.904 -8.479  1.00 39.57  ? 212 ILE A CG1 1 
ATOM   1574  C  CG2 . ILE A 1 233 ? -24.535 -16.226 -7.550  1.00 39.37  ? 212 ILE A CG2 1 
ATOM   1575  C  CD1 . ILE A 1 233 ? -23.169 -13.488 -7.334  1.00 39.12  ? 212 ILE A CD1 1 
ATOM   1576  N  N   . THR A 1 234 ? -26.611 -17.523 -9.653  1.00 35.65  ? 213 THR A N   1 
ATOM   1577  C  CA  . THR A 1 234 ? -27.397 -18.723 -9.428  1.00 37.98  ? 213 THR A CA  1 
ATOM   1578  C  C   . THR A 1 234 ? -26.675 -19.573 -8.403  1.00 35.71  ? 213 THR A C   1 
ATOM   1579  O  O   . THR A 1 234 ? -25.527 -19.958 -8.620  1.00 40.99  ? 213 THR A O   1 
ATOM   1580  C  CB  . THR A 1 234 ? -27.605 -19.523 -10.710 1.00 41.99  ? 213 THR A CB  1 
ATOM   1581  O  OG1 . THR A 1 234 ? -28.381 -18.740 -11.626 1.00 53.65  ? 213 THR A OG1 1 
ATOM   1582  C  CG2 . THR A 1 234 ? -28.357 -20.827 -10.360 1.00 36.17  ? 213 THR A CG2 1 
ATOM   1583  N  N   . ALA A 1 235 ? -27.331 -19.815 -7.278  1.00 36.29  ? 214 ALA A N   1 
ATOM   1584  C  CA  . ALA A 1 235 ? -26.814 -20.706 -6.252  1.00 31.39  ? 214 ALA A CA  1 
ATOM   1585  C  C   . ALA A 1 235 ? -27.193 -22.138 -6.595  1.00 38.01  ? 214 ALA A C   1 
ATOM   1586  O  O   . ALA A 1 235 ? -28.253 -22.387 -7.164  1.00 37.20  ? 214 ALA A O   1 
ATOM   1587  C  CB  . ALA A 1 235 ? -27.378 -20.319 -4.886  1.00 31.28  ? 214 ALA A CB  1 
ATOM   1588  N  N   . ARG A 1 236 ? -26.303 -23.069 -6.276  1.00 29.19  ? 215 ARG A N   1 
ATOM   1589  C  CA  . ARG A 1 236 ? -26.631 -24.485 -6.344  1.00 32.31  ? 215 ARG A CA  1 
ATOM   1590  C  C   . ARG A 1 236 ? -27.954 -24.748 -5.635  1.00 38.77  ? 215 ARG A C   1 
ATOM   1591  O  O   . ARG A 1 236 ? -28.121 -24.341 -4.478  1.00 38.81  ? 215 ARG A O   1 
ATOM   1592  C  CB  . ARG A 1 236 ? -25.554 -25.330 -5.659  1.00 41.06  ? 215 ARG A CB  1 
ATOM   1593  C  CG  . ARG A 1 236 ? -24.467 -25.890 -6.520  1.00 56.05  ? 215 ARG A CG  1 
ATOM   1594  C  CD  . ARG A 1 236 ? -23.784 -27.074 -5.806  1.00 56.52  ? 215 ARG A CD  1 
ATOM   1595  N  NE  . ARG A 1 236 ? -22.958 -26.695 -4.657  1.00 51.05  ? 215 ARG A NE  1 
ATOM   1596  C  CZ  . ARG A 1 236 ? -23.156 -27.115 -3.411  1.00 52.79  ? 215 ARG A CZ  1 
ATOM   1597  N  NH1 . ARG A 1 236 ? -24.197 -27.872 -3.086  1.00 46.71  ? 215 ARG A NH1 1 
ATOM   1598  N  NH2 . ARG A 1 236 ? -22.276 -26.786 -2.468  1.00 41.30  ? 215 ARG A NH2 1 
ATOM   1599  N  N   . PRO A 1 237 ? -28.892 -25.448 -6.264  1.00 37.38  ? 216 PRO A N   1 
ATOM   1600  C  CA  . PRO A 1 237 ? -30.139 -25.781 -5.570  1.00 36.73  ? 216 PRO A CA  1 
ATOM   1601  C  C   . PRO A 1 237 ? -29.855 -26.549 -4.279  1.00 32.96  ? 216 PRO A C   1 
ATOM   1602  O  O   . PRO A 1 237 ? -28.992 -27.434 -4.236  1.00 35.63  ? 216 PRO A O   1 
ATOM   1603  C  CB  . PRO A 1 237 ? -30.898 -26.632 -6.597  1.00 43.16  ? 216 PRO A CB  1 
ATOM   1604  C  CG  . PRO A 1 237 ? -30.283 -26.251 -7.927  1.00 52.96  ? 216 PRO A CG  1 
ATOM   1605  C  CD  . PRO A 1 237 ? -28.837 -26.012 -7.622  1.00 48.78  ? 216 PRO A CD  1 
ATOM   1606  N  N   . ASP A 1 238 ? -30.523 -26.121 -3.206  1.00 26.94  ? 217 ASP A N   1 
ATOM   1607  C  CA  . ASP A 1 238 ? -30.497 -26.699 -1.866  1.00 35.44  ? 217 ASP A CA  1 
ATOM   1608  C  C   . ASP A 1 238 ? -29.219 -26.389 -1.082  1.00 27.12  ? 217 ASP A C   1 
ATOM   1609  O  O   . ASP A 1 238 ? -29.029 -26.938 -0.002  1.00 27.03  ? 217 ASP A O   1 
ATOM   1610  C  CB  . ASP A 1 238 ? -30.705 -28.212 -1.914  1.00 27.31  ? 217 ASP A CB  1 
ATOM   1611  C  CG  . ASP A 1 238 ? -31.293 -28.753 -0.643  1.00 36.86  ? 217 ASP A CG  1 
ATOM   1612  O  OD1 . ASP A 1 238 ? -32.074 -28.031 0.007   1.00 35.03  ? 217 ASP A OD1 1 
ATOM   1613  O  OD2 . ASP A 1 238 ? -30.942 -29.887 -0.277  1.00 37.00  ? 217 ASP A OD2 1 
ATOM   1614  N  N   . CYS A 1 239 ? -28.347 -25.525 -1.581  1.00 27.94  ? 218 CYS A N   1 
ATOM   1615  C  CA  . CYS A 1 239 ? -27.133 -25.245 -0.816  1.00 26.99  ? 218 CYS A CA  1 
ATOM   1616  C  C   . CYS A 1 239 ? -27.416 -24.220 0.278   1.00 27.81  ? 218 CYS A C   1 
ATOM   1617  O  O   . CYS A 1 239 ? -28.465 -23.565 0.301   1.00 22.22  ? 218 CYS A O   1 
ATOM   1618  C  CB  . CYS A 1 239 ? -26.000 -24.749 -1.720  1.00 27.18  ? 218 CYS A CB  1 
ATOM   1619  S  SG  . CYS A 1 239 ? -26.149 -23.086 -2.368  1.00 27.62  ? 218 CYS A SG  1 
ATOM   1620  N  N   . VAL A 1 240 ? -26.441 -24.063 1.187   1.00 25.09  ? 219 VAL A N   1 
ATOM   1621  C  CA  . VAL A 1 240 ? -26.599 -23.131 2.307   1.00 20.54  ? 219 VAL A CA  1 
ATOM   1622  C  C   . VAL A 1 240 ? -26.881 -21.728 1.820   1.00 21.57  ? 219 VAL A C   1 
ATOM   1623  O  O   . VAL A 1 240 ? -27.741 -21.023 2.374   1.00 23.74  ? 219 VAL A O   1 
ATOM   1624  C  CB  . VAL A 1 240 ? -25.342 -23.145 3.191   1.00 23.13  ? 219 VAL A CB  1 
ATOM   1625  C  CG1 . VAL A 1 240 ? -25.493 -22.088 4.251   1.00 26.20  ? 219 VAL A CG1 1 
ATOM   1626  C  CG2 . VAL A 1 240 ? -25.193 -24.518 3.820   1.00 22.24  ? 219 VAL A CG2 1 
ATOM   1627  N  N   . LEU A 1 241 ? -26.147 -21.295 0.791   1.00 22.65  ? 220 LEU A N   1 
ATOM   1628  C  CA  . LEU A 1 241 ? -26.315 -19.941 0.278   1.00 21.83  ? 220 LEU A CA  1 
ATOM   1629  C  C   . LEU A 1 241 ? -27.733 -19.714 -0.214  1.00 26.87  ? 220 LEU A C   1 
ATOM   1630  O  O   . LEU A 1 241 ? -28.340 -18.683 0.080   1.00 25.90  ? 220 LEU A O   1 
ATOM   1631  C  CB  . LEU A 1 241 ? -25.314 -19.686 -0.845  1.00 22.98  ? 220 LEU A CB  1 
ATOM   1632  C  CG  . LEU A 1 241 ? -25.542 -18.386 -1.643  1.00 26.23  ? 220 LEU A CG  1 
ATOM   1633  C  CD1 . LEU A 1 241 ? -25.452 -17.145 -0.750  1.00 22.50  ? 220 LEU A CD1 1 
ATOM   1634  C  CD2 . LEU A 1 241 ? -24.514 -18.256 -2.776  1.00 24.16  ? 220 LEU A CD2 1 
ATOM   1635  N  N   . GLU A 1 242 ? -28.279 -20.672 -0.958  1.00 27.04  ? 221 GLU A N   1 
ATOM   1636  C  CA  . GLU A 1 242 ? -29.673 -20.560 -1.379  1.00 25.52  ? 221 GLU A CA  1 
ATOM   1637  C  C   . GLU A 1 242 ? -30.605 -20.453 -0.180  1.00 22.79  ? 221 GLU A C   1 
ATOM   1638  O  O   . GLU A 1 242 ? -31.526 -19.636 -0.177  1.00 27.10  ? 221 GLU A O   1 
ATOM   1639  C  CB  . GLU A 1 242 ? -30.065 -21.752 -2.258  1.00 26.73  ? 221 GLU A CB  1 
ATOM   1640  C  CG  . GLU A 1 242 ? -31.496 -21.672 -2.816  1.00 31.57  ? 221 GLU A CG  1 
ATOM   1641  C  CD  . GLU A 1 242 ? -31.854 -22.872 -3.692  1.00 48.99  ? 221 GLU A CD  1 
ATOM   1642  O  OE1 . GLU A 1 242 ? -32.097 -23.998 -3.166  1.00 47.98  ? 221 GLU A OE1 1 
ATOM   1643  O  OE2 . GLU A 1 242 ? -31.881 -22.691 -4.925  1.00 69.65  ? 221 GLU A OE2 1 
ATOM   1644  N  N   . HIS A 1 243 ? -30.403 -21.287 0.844   1.00 22.67  ? 222 HIS A N   1 
ATOM   1645  C  CA  . HIS A 1 243 ? -31.306 -21.229 1.983   1.00 24.40  ? 222 HIS A CA  1 
ATOM   1646  C  C   . HIS A 1 243 ? -31.176 -19.930 2.760   1.00 24.85  ? 222 HIS A C   1 
ATOM   1647  O  O   . HIS A 1 243 ? -32.144 -19.500 3.399   1.00 24.74  ? 222 HIS A O   1 
ATOM   1648  C  CB  . HIS A 1 243 ? -31.070 -22.425 2.900   1.00 21.26  ? 222 HIS A CB  1 
ATOM   1649  C  CG  . HIS A 1 243 ? -31.656 -23.687 2.364   1.00 26.19  ? 222 HIS A CG  1 
ATOM   1650  N  ND1 . HIS A 1 243 ? -32.997 -23.979 2.476   1.00 26.48  ? 222 HIS A ND1 1 
ATOM   1651  C  CD2 . HIS A 1 243 ? -31.104 -24.700 1.654   1.00 25.53  ? 222 HIS A CD2 1 
ATOM   1652  C  CE1 . HIS A 1 243 ? -33.243 -25.143 1.902   1.00 27.75  ? 222 HIS A CE1 1 
ATOM   1653  N  NE2 . HIS A 1 243 ? -32.110 -25.610 1.404   1.00 28.75  ? 222 HIS A NE2 1 
ATOM   1654  N  N   . MET A 1 244 ? -29.990 -19.323 2.779   1.00 21.50  ? 223 MET A N   1 
ATOM   1655  C  CA  . MET A 1 244 ? -29.889 -18.035 3.462   1.00 22.89  ? 223 MET A CA  1 
ATOM   1656  C  C   . MET A 1 244 ? -30.558 -16.950 2.636   1.00 25.09  ? 223 MET A C   1 
ATOM   1657  O  O   . MET A 1 244 ? -31.166 -16.023 3.189   1.00 24.41  ? 223 MET A O   1 
ATOM   1658  C  CB  . MET A 1 244 ? -28.424 -17.677 3.747   1.00 22.29  ? 223 MET A CB  1 
ATOM   1659  C  CG  . MET A 1 244 ? -27.805 -18.565 4.852   1.00 22.59  ? 223 MET A CG  1 
ATOM   1660  S  SD  . MET A 1 244 ? -28.715 -18.536 6.423   1.00 29.31  ? 223 MET A SD  1 
ATOM   1661  C  CE  . MET A 1 244 ? -29.713 -20.062 6.421   1.00 29.29  ? 223 MET A CE  1 
ATOM   1662  N  N   . ALA A 1 245 ? -30.451 -17.030 1.306   1.00 22.85  ? 224 ALA A N   1 
ATOM   1663  C  CA  . ALA A 1 245 ? -31.188 -16.063 0.492   1.00 25.89  ? 224 ALA A CA  1 
ATOM   1664  C  C   . ALA A 1 245 ? -32.698 -16.202 0.697   1.00 24.30  ? 224 ALA A C   1 
ATOM   1665  O  O   . ALA A 1 245 ? -33.442 -15.233 0.512   1.00 27.91  ? 224 ALA A O   1 
ATOM   1666  C  CB  . ALA A 1 245 ? -30.819 -16.227 -0.988  1.00 22.52  ? 224 ALA A CB  1 
ATOM   1667  N  N   . GLN A 1 246 ? -33.171 -17.397 1.058   1.00 24.42  ? 225 GLN A N   1 
ATOM   1668  C  CA  . GLN A 1 246 ? -34.586 -17.642 1.303   1.00 24.23  ? 225 GLN A CA  1 
ATOM   1669  C  C   . GLN A 1 246 ? -34.974 -17.498 2.773   1.00 26.22  ? 225 GLN A C   1 
ATOM   1670  O  O   . GLN A 1 246 ? -36.061 -17.937 3.165   1.00 28.84  ? 225 GLN A O   1 
ATOM   1671  C  CB  . GLN A 1 246 ? -34.961 -19.037 0.802   1.00 26.95  ? 225 GLN A CB  1 
ATOM   1672  C  CG  . GLN A 1 246 ? -34.698 -19.211 -0.710  1.00 29.41  ? 225 GLN A CG  1 
ATOM   1673  C  CD  . GLN A 1 246 ? -34.934 -20.646 -1.202  1.00 39.82  ? 225 GLN A CD  1 
ATOM   1674  O  OE1 . GLN A 1 246 ? -34.852 -21.606 -0.438  1.00 45.19  ? 225 GLN A OE1 1 
ATOM   1675  N  NE2 . GLN A 1 246 ? -35.203 -20.785 -2.486  1.00 47.61  ? 225 GLN A NE2 1 
ATOM   1676  N  N   . LEU A 1 247 ? -34.112 -16.914 3.592   1.00 24.65  ? 226 LEU A N   1 
ATOM   1677  C  CA  . LEU A 1 247 ? -34.363 -16.854 5.028   1.00 22.41  ? 226 LEU A CA  1 
ATOM   1678  C  C   . LEU A 1 247 ? -35.616 -16.027 5.297   1.00 25.60  ? 226 LEU A C   1 
ATOM   1679  O  O   . LEU A 1 247 ? -35.741 -14.913 4.787   1.00 27.17  ? 226 LEU A O   1 
ATOM   1680  C  CB  . LEU A 1 247 ? -33.160 -16.202 5.713   1.00 26.37  ? 226 LEU A CB  1 
ATOM   1681  C  CG  . LEU A 1 247 ? -33.000 -16.224 7.228   1.00 32.65  ? 226 LEU A CG  1 
ATOM   1682  C  CD1 . LEU A 1 247 ? -32.911 -17.652 7.799   1.00 25.14  ? 226 LEU A CD1 1 
ATOM   1683  C  CD2 . LEU A 1 247 ? -31.741 -15.420 7.621   1.00 30.80  ? 226 LEU A CD2 1 
ATOM   1684  N  N   . THR A 1 248 ? -36.537 -16.566 6.107   1.00 25.21  ? 227 THR A N   1 
ATOM   1685  C  CA  . THR A 1 248 ? -37.780 -15.884 6.411   1.00 26.76  ? 227 THR A CA  1 
ATOM   1686  C  C   . THR A 1 248 ? -37.976 -15.807 7.915   1.00 24.61  ? 227 THR A C   1 
ATOM   1687  O  O   . THR A 1 248 ? -37.338 -16.528 8.694   1.00 25.86  ? 227 THR A O   1 
ATOM   1688  C  CB  . THR A 1 248 ? -38.998 -16.599 5.763   1.00 28.42  ? 227 THR A CB  1 
ATOM   1689  O  OG1 . THR A 1 248 ? -39.012 -17.976 6.168   1.00 29.31  ? 227 THR A OG1 1 
ATOM   1690  C  CG2 . THR A 1 248 ? -38.910 -16.518 4.249   1.00 29.33  ? 227 THR A CG2 1 
ATOM   1691  N  N   . ASP A 1 249 ? -38.862 -14.897 8.327   1.00 27.84  ? 228 ASP A N   1 
ATOM   1692  C  CA  . ASP A 1 249 ? -39.142 -14.691 9.739   1.00 22.81  ? 228 ASP A CA  1 
ATOM   1693  C  C   . ASP A 1 249 ? -40.445 -15.389 10.127  1.00 25.16  ? 228 ASP A C   1 
ATOM   1694  O  O   . ASP A 1 249 ? -41.054 -16.105 9.328   1.00 27.34  ? 228 ASP A O   1 
ATOM   1695  C  CB  . ASP A 1 249 ? -39.130 -13.184 10.031  1.00 27.30  ? 228 ASP A CB  1 
ATOM   1696  C  CG  . ASP A 1 249 ? -40.279 -12.434 9.369   1.00 36.61  ? 228 ASP A CG  1 
ATOM   1697  O  OD1 . ASP A 1 249 ? -41.270 -13.062 8.903   1.00 33.92  ? 228 ASP A OD1 1 
ATOM   1698  O  OD2 . ASP A 1 249 ? -40.185 -11.192 9.312   1.00 34.84  ? 228 ASP A OD2 1 
ATOM   1699  N  N   . ALA A 1 250 ? -40.893 -15.197 11.370  1.00 22.75  ? 229 ALA A N   1 
ATOM   1700  C  CA  . ALA A 1 250 ? -42.048 -15.969 11.833  1.00 25.02  ? 229 ALA A CA  1 
ATOM   1701  C  C   . ALA A 1 250 ? -43.330 -15.597 11.093  1.00 33.74  ? 229 ALA A C   1 
ATOM   1702  O  O   . ALA A 1 250 ? -44.264 -16.405 11.026  1.00 30.33  ? 229 ALA A O   1 
ATOM   1703  C  CB  . ALA A 1 250 ? -42.260 -15.784 13.341  1.00 28.75  ? 229 ALA A CB  1 
ATOM   1704  N  N   . SER A 1 251 ? -43.400 -14.395 10.537  1.00 25.99  ? 230 SER A N   1 
ATOM   1705  C  CA  . SER A 1 251 ? -44.564 -14.000 9.761   1.00 32.91  ? 230 SER A CA  1 
ATOM   1706  C  C   . SER A 1 251 ? -44.527 -14.508 8.314   1.00 35.14  ? 230 SER A C   1 
ATOM   1707  O  O   . SER A 1 251 ? -45.508 -14.335 7.583   1.00 33.04  ? 230 SER A O   1 
ATOM   1708  C  CB  . SER A 1 251 ? -44.696 -12.477 9.803   1.00 32.64  ? 230 SER A CB  1 
ATOM   1709  O  OG  . SER A 1 251 ? -43.808 -11.863 8.884   1.00 41.47  ? 230 SER A OG  1 
ATOM   1710  N  N   . GLY A 1 252 ? -43.441 -15.147 7.882   1.00 28.91  ? 231 GLY A N   1 
ATOM   1711  C  CA  . GLY A 1 252 ? -43.336 -15.668 6.534   1.00 33.18  ? 231 GLY A CA  1 
ATOM   1712  C  C   . GLY A 1 252 ? -42.633 -14.746 5.558   1.00 37.87  ? 231 GLY A C   1 
ATOM   1713  O  O   . GLY A 1 252 ? -42.358 -15.158 4.423   1.00 34.83  ? 231 GLY A O   1 
ATOM   1714  N  N   . GLU A 1 253 ? -42.295 -13.537 5.986   1.00 28.79  ? 232 GLU A N   1 
ATOM   1715  C  CA  . GLU A 1 253 ? -41.647 -12.550 5.145   1.00 24.25  ? 232 GLU A CA  1 
ATOM   1716  C  C   . GLU A 1 253 ? -40.142 -12.783 5.098   1.00 30.34  ? 232 GLU A C   1 
ATOM   1717  O  O   . GLU A 1 253 ? -39.535 -13.224 6.085   1.00 26.96  ? 232 GLU A O   1 
ATOM   1718  C  CB  . GLU A 1 253 ? -41.912 -11.146 5.703   1.00 31.67  ? 232 GLU A CB  1 
ATOM   1719  C  CG  . GLU A 1 253 ? -43.397 -10.793 5.872   1.00 49.73  ? 232 GLU A CG  1 
ATOM   1720  C  CD  . GLU A 1 253 ? -44.125 -10.607 4.544   1.00 70.31  ? 232 GLU A CD  1 
ATOM   1721  O  OE1 . GLU A 1 253 ? -43.452 -10.508 3.491   1.00 74.65  ? 232 GLU A OE1 1 
ATOM   1722  O  OE2 . GLU A 1 253 ? -45.377 -10.558 4.556   1.00 96.01  ? 232 GLU A OE2 1 
ATOM   1723  N  N   . ARG A 1 254 ? -39.529 -12.451 3.955   1.00 29.19  ? 233 ARG A N   1 
ATOM   1724  C  CA  . ARG A 1 254 ? -38.081 -12.565 3.850   1.00 29.13  ? 233 ARG A CA  1 
ATOM   1725  C  C   . ARG A 1 254 ? -37.379 -11.642 4.844   1.00 25.65  ? 233 ARG A C   1 
ATOM   1726  O  O   . ARG A 1 254 ? -37.763 -10.484 5.038   1.00 26.40  ? 233 ARG A O   1 
ATOM   1727  C  CB  . ARG A 1 254 ? -37.613 -12.226 2.436   1.00 35.72  ? 233 ARG A CB  1 
ATOM   1728  C  CG  . ARG A 1 254 ? -37.995 -13.279 1.416   1.00 50.58  ? 233 ARG A CG  1 
ATOM   1729  C  CD  . ARG A 1 254 ? -36.765 -13.950 0.881   1.00 45.06  ? 233 ARG A CD  1 
ATOM   1730  N  NE  . ARG A 1 254 ? -37.055 -14.928 -0.163  1.00 49.49  ? 233 ARG A NE  1 
ATOM   1731  C  CZ  . ARG A 1 254 ? -36.780 -14.769 -1.454  1.00 50.27  ? 233 ARG A CZ  1 
ATOM   1732  N  NH1 . ARG A 1 254 ? -36.280 -13.633 -1.931  1.00 38.08  ? 233 ARG A NH1 1 
ATOM   1733  N  NH2 . ARG A 1 254 ? -37.019 -15.775 -2.292  1.00 52.77  ? 233 ARG A NH2 1 
ATOM   1734  N  N   . VAL A 1 255 ? -36.303 -12.151 5.435   1.00 26.82  ? 234 VAL A N   1 
ATOM   1735  C  CA  . VAL A 1 255 ? -35.418 -11.302 6.219   1.00 26.90  ? 234 VAL A CA  1 
ATOM   1736  C  C   . VAL A 1 255 ? -34.620 -10.400 5.287   1.00 25.01  ? 234 VAL A C   1 
ATOM   1737  O  O   . VAL A 1 255 ? -34.272 -10.780 4.163   1.00 28.99  ? 234 VAL A O   1 
ATOM   1738  C  CB  . VAL A 1 255 ? -34.517 -12.212 7.070   1.00 28.82  ? 234 VAL A CB  1 
ATOM   1739  C  CG1 . VAL A 1 255 ? -33.579 -11.407 7.904   1.00 38.27  ? 234 VAL A CG1 1 
ATOM   1740  C  CG2 . VAL A 1 255 ? -35.416 -13.070 7.981   1.00 27.58  ? 234 VAL A CG2 1 
ATOM   1741  N  N   . ASP A 1 256 ? -34.332 -9.175  5.740   1.00 24.13  ? 235 ASP A N   1 
ATOM   1742  C  CA  . ASP A 1 256 ? -33.621 -8.259  4.860   1.00 31.33  ? 235 ASP A CA  1 
ATOM   1743  C  C   . ASP A 1 256 ? -32.237 -8.811  4.494   1.00 26.92  ? 235 ASP A C   1 
ATOM   1744  O  O   . ASP A 1 256 ? -31.680 -9.694  5.160   1.00 29.31  ? 235 ASP A O   1 
ATOM   1745  C  CB  . ASP A 1 256 ? -33.492 -6.885  5.500   1.00 36.64  ? 235 ASP A CB  1 
ATOM   1746  C  CG  . ASP A 1 256 ? -32.596 -6.914  6.709   1.00 40.52  ? 235 ASP A CG  1 
ATOM   1747  O  OD1 . ASP A 1 256 ? -33.086 -7.303  7.794   1.00 46.04  ? 235 ASP A OD1 1 
ATOM   1748  O  OD2 . ASP A 1 256 ? -31.394 -6.611  6.548   1.00 40.93  ? 235 ASP A OD2 1 
ATOM   1749  N  N   . ALA A 1 257 ? -31.705 -8.297  3.390   1.00 25.88  ? 236 ALA A N   1 
ATOM   1750  C  CA  . ALA A 1 257 ? -30.567 -8.937  2.744   1.00 30.05  ? 236 ALA A CA  1 
ATOM   1751  C  C   . ALA A 1 257 ? -29.310 -8.849  3.585   1.00 26.33  ? 236 ALA A C   1 
ATOM   1752  O  O   . ALA A 1 257 ? -28.487 -9.774  3.541   1.00 27.10  ? 236 ALA A O   1 
ATOM   1753  C  CB  . ALA A 1 257 ? -30.285 -8.309  1.378   1.00 25.16  ? 236 ALA A CB  1 
ATOM   1754  N  N   . ARG A 1 258 ? -29.122 -7.748  4.324   1.00 25.44  ? 237 ARG A N   1 
ATOM   1755  C  CA  . ARG A 1 258 ? -27.923 -7.630  5.144   1.00 26.67  ? 237 ARG A CA  1 
ATOM   1756  C  C   . ARG A 1 258 ? -27.971 -8.596  6.321   1.00 23.48  ? 237 ARG A C   1 
ATOM   1757  O  O   . ARG A 1 258 ? -26.959 -9.209  6.664   1.00 24.75  ? 237 ARG A O   1 
ATOM   1758  C  CB  . ARG A 1 258 ? -27.734 -6.188  5.639   1.00 25.62  ? 237 ARG A CB  1 
ATOM   1759  C  CG  . ARG A 1 258 ? -26.314 -5.931  6.218   1.00 24.92  ? 237 ARG A CG  1 
ATOM   1760  C  CD  . ARG A 1 258 ? -26.144 -4.453  6.649   1.00 29.60  ? 237 ARG A CD  1 
ATOM   1761  N  NE  . ARG A 1 258 ? -24.771 -4.090  7.003   1.00 25.66  ? 237 ARG A NE  1 
ATOM   1762  C  CZ  . ARG A 1 258 ? -23.835 -3.764  6.119   1.00 28.92  ? 237 ARG A CZ  1 
ATOM   1763  N  NH1 . ARG A 1 258 ? -24.063 -3.842  4.822   1.00 26.64  ? 237 ARG A NH1 1 
ATOM   1764  N  NH2 . ARG A 1 258 ? -22.641 -3.327  6.547   1.00 30.77  ? 237 ARG A NH2 1 
ATOM   1765  N  N   . THR A 1 259 ? -29.131 -8.734  6.958   1.00 21.60  ? 238 THR A N   1 
ATOM   1766  C  CA  . THR A 1 259 ? -29.273 -9.730  8.014   1.00 23.54  ? 238 THR A CA  1 
ATOM   1767  C  C   . THR A 1 259 ? -29.076 -11.139 7.477   1.00 24.91  ? 238 THR A C   1 
ATOM   1768  O  O   . THR A 1 259 ? -28.436 -11.964 8.128   1.00 23.91  ? 238 THR A O   1 
ATOM   1769  C  CB  . THR A 1 259 ? -30.651 -9.622  8.666   1.00 29.87  ? 238 THR A CB  1 
ATOM   1770  O  OG1 . THR A 1 259 ? -30.790 -8.311  9.188   1.00 27.32  ? 238 THR A OG1 1 
ATOM   1771  C  CG2 . THR A 1 259 ? -30.817 -10.661 9.809   1.00 22.25  ? 238 THR A CG2 1 
ATOM   1772  N  N   . ALA A 1 260 ? -29.643 -11.447 6.305   1.00 20.76  ? 239 ALA A N   1 
ATOM   1773  C  CA  . ALA A 1 260 ? -29.397 -12.766 5.722   1.00 23.19  ? 239 ALA A CA  1 
ATOM   1774  C  C   . ALA A 1 260 ? -27.909 -12.988 5.455   1.00 20.55  ? 239 ALA A C   1 
ATOM   1775  O  O   . ALA A 1 260 ? -27.405 -14.106 5.641   1.00 22.21  ? 239 ALA A O   1 
ATOM   1776  C  CB  . ALA A 1 260 ? -30.212 -12.965 4.437   1.00 20.48  ? 239 ALA A CB  1 
ATOM   1777  N  N   . GLY A 1 261 ? -27.189 -11.951 5.013   1.00 21.64  ? 240 GLY A N   1 
ATOM   1778  C  CA  . GLY A 1 261 ? -25.762 -12.108 4.805   1.00 21.09  ? 240 GLY A CA  1 
ATOM   1779  C  C   . GLY A 1 261 ? -25.000 -12.275 6.102   1.00 23.47  ? 240 GLY A C   1 
ATOM   1780  O  O   . GLY A 1 261 ? -23.982 -12.976 6.146   1.00 21.88  ? 240 GLY A O   1 
ATOM   1781  N  N   . ILE A 1 262 ? -25.457 -11.611 7.161   1.00 21.06  ? 241 ILE A N   1 
ATOM   1782  C  CA  . ILE A 1 262 ? -24.911 -11.856 8.498   1.00 22.56  ? 241 ILE A CA  1 
ATOM   1783  C  C   . ILE A 1 262 ? -25.118 -13.316 8.918   1.00 26.50  ? 241 ILE A C   1 
ATOM   1784  O  O   . ILE A 1 262 ? -24.226 -13.938 9.498   1.00 22.93  ? 241 ILE A O   1 
ATOM   1785  C  CB  . ILE A 1 262 ? -25.535 -10.858 9.491   1.00 25.77  ? 241 ILE A CB  1 
ATOM   1786  C  CG1 . ILE A 1 262 ? -24.823 -9.495  9.334   1.00 25.05  ? 241 ILE A CG1 1 
ATOM   1787  C  CG2 . ILE A 1 262 ? -25.518 -11.388 10.954  1.00 24.14  ? 241 ILE A CG2 1 
ATOM   1788  C  CD1 . ILE A 1 262 ? -25.743 -8.341  9.680   1.00 25.29  ? 241 ILE A CD1 1 
ATOM   1789  N  N   . GLU A 1 263 ? -26.274 -13.899 8.608   1.00 25.04  ? 242 GLU A N   1 
ATOM   1790  C  CA  . GLU A 1 263 ? -26.473 -15.292 8.974   1.00 22.71  ? 242 GLU A CA  1 
ATOM   1791  C  C   . GLU A 1 263 ? -25.656 -16.238 8.106   1.00 20.07  ? 242 GLU A C   1 
ATOM   1792  O  O   . GLU A 1 263 ? -25.168 -17.252 8.608   1.00 20.29  ? 242 GLU A O   1 
ATOM   1793  C  CB  . GLU A 1 263 ? -27.963 -15.660 8.957   1.00 20.44  ? 242 GLU A CB  1 
ATOM   1794  C  CG  . GLU A 1 263 ? -28.771 -14.823 9.983   1.00 25.02  ? 242 GLU A CG  1 
ATOM   1795  C  CD  . GLU A 1 263 ? -28.399 -15.038 11.465  1.00 30.66  ? 242 GLU A CD  1 
ATOM   1796  O  OE1 . GLU A 1 263 ? -27.242 -15.374 11.790  1.00 27.74  ? 242 GLU A OE1 1 
ATOM   1797  O  OE2 . GLU A 1 263 ? -29.281 -14.834 12.333  1.00 27.92  ? 242 GLU A OE2 1 
ATOM   1798  N  N   . LEU A 1 264 ? -25.439 -15.909 6.841   1.00 20.41  ? 243 LEU A N   1 
ATOM   1799  C  CA  . LEU A 1 264 ? -24.503 -16.705 6.034   1.00 22.43  ? 243 LEU A CA  1 
ATOM   1800  C  C   . LEU A 1 264 ? -23.103 -16.688 6.656   1.00 21.68  ? 243 LEU A C   1 
ATOM   1801  O  O   . LEU A 1 264 ? -22.404 -17.705 6.654   1.00 23.12  ? 243 LEU A O   1 
ATOM   1802  C  CB  . LEU A 1 264 ? -24.439 -16.157 4.618   1.00 21.37  ? 243 LEU A CB  1 
ATOM   1803  C  CG  . LEU A 1 264 ? -23.510 -16.880 3.637   1.00 21.88  ? 243 LEU A CG  1 
ATOM   1804  C  CD1 . LEU A 1 264 ? -24.116 -18.247 3.311   1.00 22.49  ? 243 LEU A CD1 1 
ATOM   1805  C  CD2 . LEU A 1 264 ? -23.399 -15.995 2.391   1.00 25.47  ? 243 LEU A CD2 1 
ATOM   1806  N  N   . GLN A 1 265 ? -22.663 -15.523 7.145   1.00 19.55  ? 244 GLN A N   1 
ATOM   1807  C  CA  . GLN A 1 265 ? -21.384 -15.467 7.852   1.00 18.14  ? 244 GLN A CA  1 
ATOM   1808  C  C   . GLN A 1 265 ? -21.415 -16.285 9.148   1.00 19.40  ? 244 GLN A C   1 
ATOM   1809  O  O   . GLN A 1 265 ? -20.390 -16.863 9.539   1.00 22.27  ? 244 GLN A O   1 
ATOM   1810  C  CB  . GLN A 1 265 ? -21.020 -14.028 8.168   1.00 21.43  ? 244 GLN A CB  1 
ATOM   1811  C  CG  . GLN A 1 265 ? -20.616 -13.196 6.961   1.00 25.14  ? 244 GLN A CG  1 
ATOM   1812  C  CD  . GLN A 1 265 ? -20.503 -11.737 7.336   1.00 30.10  ? 244 GLN A CD  1 
ATOM   1813  O  OE1 . GLN A 1 265 ? -19.540 -11.326 7.992   1.00 29.15  ? 244 GLN A OE1 1 
ATOM   1814  N  NE2 . GLN A 1 265 ? -21.514 -10.961 6.993   1.00 25.63  ? 244 GLN A NE2 1 
ATOM   1815  N  N   . ASN A 1 266 ? -22.556 -16.336 9.826   1.00 18.68  ? 245 ASN A N   1 
ATOM   1816  C  CA  . ASN A 1 266 ? -22.656 -17.150 11.040  1.00 19.50  ? 245 ASN A CA  1 
ATOM   1817  C  C   . ASN A 1 266 ? -22.703 -18.640 10.746  1.00 20.17  ? 245 ASN A C   1 
ATOM   1818  O  O   . ASN A 1 266 ? -22.767 -19.434 11.692  1.00 23.03  ? 245 ASN A O   1 
ATOM   1819  C  CB  . ASN A 1 266 ? -23.865 -16.723 11.886  1.00 19.63  ? 245 ASN A CB  1 
ATOM   1820  C  CG  . ASN A 1 266 ? -23.645 -15.382 12.572  1.00 22.95  ? 245 ASN A CG  1 
ATOM   1821  O  OD1 . ASN A 1 266 ? -22.526 -15.042 12.928  1.00 27.42  ? 245 ASN A OD1 1 
ATOM   1822  N  ND2 . ASN A 1 266 ? -24.717 -14.607 12.747  1.00 22.60  ? 245 ASN A ND2 1 
ATOM   1823  N  N   . LEU A 1 267 ? -22.656 -19.050 9.476   1.00 20.45  ? 246 LEU A N   1 
ATOM   1824  C  CA  . LEU A 1 267 ? -22.505 -20.463 9.149   1.00 23.76  ? 246 LEU A CA  1 
ATOM   1825  C  C   . LEU A 1 267 ? -21.198 -20.757 8.434   1.00 23.08  ? 246 LEU A C   1 
ATOM   1826  O  O   . LEU A 1 267 ? -21.015 -21.878 7.970   1.00 25.07  ? 246 LEU A O   1 
ATOM   1827  C  CB  . LEU A 1 267 ? -23.690 -20.961 8.299   1.00 19.13  ? 246 LEU A CB  1 
ATOM   1828  C  CG  . LEU A 1 267 ? -25.070 -20.862 8.935   1.00 25.35  ? 246 LEU A CG  1 
ATOM   1829  C  CD1 . LEU A 1 267 ? -26.177 -21.190 7.915   1.00 26.03  ? 246 LEU A CD1 1 
ATOM   1830  C  CD2 . LEU A 1 267 ? -25.135 -21.792 10.178  1.00 25.30  ? 246 LEU A CD2 1 
ATOM   1831  N  N   . THR A 1 268 ? -20.261 -19.809 8.391   1.00 20.59  ? 247 THR A N   1 
ATOM   1832  C  CA  . THR A 1 268 ? -18.981 -20.004 7.719   1.00 21.12  ? 247 THR A CA  1 
ATOM   1833  C  C   . THR A 1 268 ? -17.842 -19.496 8.604   1.00 24.00  ? 247 THR A C   1 
ATOM   1834  O  O   . THR A 1 268 ? -16.850 -20.205 8.797   1.00 21.89  ? 247 THR A O   1 
ATOM   1835  C  CB  . THR A 1 268 ? -18.959 -19.300 6.346   1.00 26.14  ? 247 THR A CB  1 
ATOM   1836  O  OG1 . THR A 1 268 ? -19.500 -17.975 6.457   1.00 23.32  ? 247 THR A OG1 1 
ATOM   1837  C  CG2 . THR A 1 268 ? -19.811 -20.075 5.318   1.00 24.75  ? 247 THR A CG2 1 
ATOM   1838  N  N   . ARG A 1 269 ? -17.967 -18.278 9.142   1.00 21.75  ? 248 ARG A N   1 
ATOM   1839  C  CA  . ARG A 1 269 ? -16.931 -17.763 10.039  1.00 19.90  ? 248 ARG A CA  1 
ATOM   1840  C  C   . ARG A 1 269 ? -16.681 -18.659 11.262  1.00 19.38  ? 248 ARG A C   1 
ATOM   1841  O  O   . ARG A 1 269 ? -15.508 -18.861 11.601  1.00 18.43  ? 248 ARG A O   1 
ATOM   1842  C  CB  . ARG A 1 269 ? -17.284 -16.325 10.484  1.00 17.15  ? 248 ARG A CB  1 
ATOM   1843  C  CG  . ARG A 1 269 ? -16.249 -15.718 11.481  1.00 21.16  ? 248 ARG A CG  1 
ATOM   1844  C  CD  . ARG A 1 269 ? -16.922 -14.603 12.385  1.00 19.86  ? 248 ARG A CD  1 
ATOM   1845  N  NE  . ARG A 1 269 ? -17.897 -15.169 13.305  1.00 23.71  ? 248 ARG A NE  1 
ATOM   1846  C  CZ  . ARG A 1 269 ? -19.217 -15.094 13.131  1.00 22.44  ? 248 ARG A CZ  1 
ATOM   1847  N  NH1 . ARG A 1 269 ? -19.745 -14.458 12.103  1.00 21.77  ? 248 ARG A NH1 1 
ATOM   1848  N  NH2 . ARG A 1 269 ? -20.021 -15.661 14.017  1.00 23.65  ? 248 ARG A NH2 1 
ATOM   1849  N  N   . PRO A 1 270 ? -17.682 -19.222 11.949  1.00 20.15  ? 249 PRO A N   1 
ATOM   1850  C  CA  . PRO A 1 270 ? -17.369 -20.090 13.102  1.00 19.26  ? 249 PRO A CA  1 
ATOM   1851  C  C   . PRO A 1 270 ? -16.608 -21.351 12.694  1.00 23.82  ? 249 PRO A C   1 
ATOM   1852  O  O   . PRO A 1 270 ? -15.841 -21.893 13.499  1.00 19.93  ? 249 PRO A O   1 
ATOM   1853  C  CB  . PRO A 1 270 ? -18.751 -20.420 13.677  1.00 17.88  ? 249 PRO A CB  1 
ATOM   1854  C  CG  . PRO A 1 270 ? -19.670 -19.318 13.198  1.00 19.96  ? 249 PRO A CG  1 
ATOM   1855  C  CD  . PRO A 1 270 ? -19.148 -19.003 11.811  1.00 17.01  ? 249 PRO A CD  1 
ATOM   1856  N  N   . THR A 1 271 ? -16.726 -21.794 11.434  1.00 17.16  ? 250 THR A N   1 
ATOM   1857  C  CA  . THR A 1 271 ? -15.884 -22.898 10.989  1.00 16.47  ? 250 THR A CA  1 
ATOM   1858  C  C   . THR A 1 271 ? -14.429 -22.466 10.888  1.00 20.83  ? 250 THR A C   1 
ATOM   1859  O  O   . THR A 1 271 ? -13.520 -23.213 11.275  1.00 21.22  ? 250 THR A O   1 
ATOM   1860  C  CB  . THR A 1 271 ? -16.393 -23.400 9.633   1.00 19.96  ? 250 THR A CB  1 
ATOM   1861  O  OG1 . THR A 1 271 ? -17.805 -23.698 9.768   1.00 21.19  ? 250 THR A OG1 1 
ATOM   1862  C  CG2 . THR A 1 271 ? -15.638 -24.663 9.226   1.00 20.63  ? 250 THR A CG2 1 
ATOM   1863  N  N   . VAL A 1 272 ? -14.194 -21.254 10.374  1.00 20.64  ? 251 VAL A N   1 
ATOM   1864  C  CA  . VAL A 1 272 ? -12.844 -20.685 10.404  1.00 20.09  ? 251 VAL A CA  1 
ATOM   1865  C  C   . VAL A 1 272 ? -12.301 -20.678 11.821  1.00 20.89  ? 251 VAL A C   1 
ATOM   1866  O  O   . VAL A 1 272 ? -11.115 -20.963 12.044  1.00 19.50  ? 251 VAL A O   1 
ATOM   1867  C  CB  . VAL A 1 272 ? -12.850 -19.260 9.798   1.00 17.75  ? 251 VAL A CB  1 
ATOM   1868  C  CG1 . VAL A 1 272 ? -11.420 -18.682 9.792   1.00 17.02  ? 251 VAL A CG1 1 
ATOM   1869  C  CG2 . VAL A 1 272 ? -13.351 -19.313 8.379   1.00 18.29  ? 251 VAL A CG2 1 
ATOM   1870  N  N   . ALA A 1 273 ? -13.163 -20.358 12.802  1.00 20.76  ? 252 ALA A N   1 
ATOM   1871  C  CA  . ALA A 1 273 ? -12.759 -20.228 14.202  1.00 21.38  ? 252 ALA A CA  1 
ATOM   1872  C  C   . ALA A 1 273 ? -12.312 -21.551 14.807  1.00 21.05  ? 252 ALA A C   1 
ATOM   1873  O  O   . ALA A 1 273 ? -11.633 -21.539 15.846  1.00 19.27  ? 252 ALA A O   1 
ATOM   1874  C  CB  . ALA A 1 273 ? -13.915 -19.648 15.048  1.00 19.15  ? 252 ALA A CB  1 
ATOM   1875  N  N   . VAL A 1 274 ? -12.615 -22.688 14.164  1.00 19.12  ? 253 VAL A N   1 
ATOM   1876  C  CA  . VAL A 1 274 ? -12.060 -23.952 14.659  1.00 16.51  ? 253 VAL A CA  1 
ATOM   1877  C  C   . VAL A 1 274 ? -10.531 -23.935 14.620  1.00 18.22  ? 253 VAL A C   1 
ATOM   1878  O  O   . VAL A 1 274 ? -9.892  -24.743 15.288  1.00 21.00  ? 253 VAL A O   1 
ATOM   1879  C  CB  . VAL A 1 274 ? -12.653 -25.154 13.868  1.00 17.81  ? 253 VAL A CB  1 
ATOM   1880  C  CG1 . VAL A 1 274 ? -12.200 -26.523 14.447  1.00 21.07  ? 253 VAL A CG1 1 
ATOM   1881  C  CG2 . VAL A 1 274 ? -14.205 -25.099 13.900  1.00 19.23  ? 253 VAL A CG2 1 
ATOM   1882  N  N   . GLY A 1 275 ? -9.938  -23.034 13.831  1.00 21.24  ? 254 GLY A N   1 
ATOM   1883  C  CA  . GLY A 1 275 ? -8.496  -22.860 13.816  1.00 18.90  ? 254 GLY A CA  1 
ATOM   1884  C  C   . GLY A 1 275 ? -7.906  -22.613 15.203  1.00 17.33  ? 254 GLY A C   1 
ATOM   1885  O  O   . GLY A 1 275 ? -6.757  -22.949 15.447  1.00 20.01  ? 254 GLY A O   1 
ATOM   1886  N  N   . PHE A 1 276 ? -8.664  -21.981 16.109  1.00 20.07  ? 255 PHE A N   1 
ATOM   1887  C  CA  . PHE A 1 276 ? -8.173  -21.831 17.475  1.00 17.57  ? 255 PHE A CA  1 
ATOM   1888  C  C   . PHE A 1 276 ? -8.013  -23.186 18.148  1.00 22.23  ? 255 PHE A C   1 
ATOM   1889  O  O   . PHE A 1 276 ? -6.968  -23.468 18.739  1.00 20.43  ? 255 PHE A O   1 
ATOM   1890  C  CB  . PHE A 1 276 ? -9.108  -20.923 18.317  1.00 19.11  ? 255 PHE A CB  1 
ATOM   1891  C  CG  . PHE A 1 276 ? -8.991  -19.463 17.950  1.00 24.63  ? 255 PHE A CG  1 
ATOM   1892  C  CD1 . PHE A 1 276 ? -9.763  -18.934 16.907  1.00 19.75  ? 255 PHE A CD1 1 
ATOM   1893  C  CD2 . PHE A 1 276 ? -8.086  -18.627 18.607  1.00 23.37  ? 255 PHE A CD2 1 
ATOM   1894  C  CE1 . PHE A 1 276 ? -9.638  -17.588 16.541  1.00 22.48  ? 255 PHE A CE1 1 
ATOM   1895  C  CE2 . PHE A 1 276 ? -7.966  -17.275 18.233  1.00 22.61  ? 255 PHE A CE2 1 
ATOM   1896  C  CZ  . PHE A 1 276 ? -8.734  -16.765 17.236  1.00 22.30  ? 255 PHE A CZ  1 
ATOM   1897  N  N   . PHE A 1 277 ? -9.055  -24.042 18.090  1.00 19.02  ? 256 PHE A N   1 
ATOM   1898  C  CA  . PHE A 1 277 ? -8.915  -25.401 18.624  1.00 19.40  ? 256 PHE A CA  1 
ATOM   1899  C  C   . PHE A 1 277 ? -7.835  -26.197 17.883  1.00 22.60  ? 256 PHE A C   1 
ATOM   1900  O  O   . PHE A 1 277 ? -7.162  -27.025 18.493  1.00 20.15  ? 256 PHE A O   1 
ATOM   1901  C  CB  . PHE A 1 277 ? -10.249 -26.157 18.544  1.00 16.25  ? 256 PHE A CB  1 
ATOM   1902  C  CG  . PHE A 1 277 ? -11.234 -25.818 19.679  1.00 19.25  ? 256 PHE A CG  1 
ATOM   1903  C  CD1 . PHE A 1 277 ? -10.792 -25.707 20.995  1.00 22.71  ? 256 PHE A CD1 1 
ATOM   1904  C  CD2 . PHE A 1 277 ? -12.590 -25.709 19.414  1.00 21.17  ? 256 PHE A CD2 1 
ATOM   1905  C  CE1 . PHE A 1 277 ? -11.698 -25.448 22.049  1.00 20.73  ? 256 PHE A CE1 1 
ATOM   1906  C  CE2 . PHE A 1 277 ? -13.496 -25.433 20.438  1.00 20.92  ? 256 PHE A CE2 1 
ATOM   1907  C  CZ  . PHE A 1 277 ? -13.045 -25.304 21.762  1.00 19.18  ? 256 PHE A CZ  1 
ATOM   1908  N  N   . ALA A 1 278 ? -7.668  -25.984 16.575  1.00 19.12  ? 257 ALA A N   1 
ATOM   1909  C  CA  . ALA A 1 278 ? -6.627  -26.739 15.876  1.00 17.79  ? 257 ALA A CA  1 
ATOM   1910  C  C   . ALA A 1 278 ? -5.238  -26.366 16.380  1.00 20.52  ? 257 ALA A C   1 
ATOM   1911  O  O   . ALA A 1 278 ? -4.359  -27.237 16.461  1.00 21.22  ? 257 ALA A O   1 
ATOM   1912  C  CB  . ALA A 1 278 ? -6.732  -26.530 14.357  1.00 19.17  ? 257 ALA A CB  1 
ATOM   1913  N  N   . SER A 1 279 ? -5.009  -25.075 16.685  1.00 20.33  ? 258 SER A N   1 
ATOM   1914  C  CA  . SER A 1 279 ? -3.722  -24.658 17.272  1.00 18.30  ? 258 SER A CA  1 
ATOM   1915  C  C   . SER A 1 279 ? -3.488  -25.340 18.617  1.00 19.81  ? 258 SER A C   1 
ATOM   1916  O  O   . SER A 1 279 ? -2.411  -25.888 18.872  1.00 19.11  ? 258 SER A O   1 
ATOM   1917  C  CB  . SER A 1 279 ? -3.683  -23.128 17.464  1.00 22.74  ? 258 SER A CB  1 
ATOM   1918  O  OG  . SER A 1 279 ? -3.782  -22.542 16.209  1.00 35.96  ? 258 SER A OG  1 
ATOM   1919  N  N   . PHE A 1 280 ? -4.502  -25.330 19.491  1.00 21.21  ? 259 PHE A N   1 
ATOM   1920  C  CA  . PHE A 1 280 ? -4.387  -26.063 20.753  1.00 19.38  ? 259 PHE A CA  1 
ATOM   1921  C  C   . PHE A 1 280 ? -4.188  -27.559 20.515  1.00 20.34  ? 259 PHE A C   1 
ATOM   1922  O  O   . PHE A 1 280 ? -3.524  -28.224 21.303  1.00 19.84  ? 259 PHE A O   1 
ATOM   1923  C  CB  . PHE A 1 280 ? -5.637  -25.857 21.630  1.00 19.34  ? 259 PHE A CB  1 
ATOM   1924  C  CG  . PHE A 1 280 ? -5.741  -24.477 22.242  1.00 22.48  ? 259 PHE A CG  1 
ATOM   1925  C  CD1 . PHE A 1 280 ? -4.703  -23.956 22.998  1.00 22.76  ? 259 PHE A CD1 1 
ATOM   1926  C  CD2 . PHE A 1 280 ? -6.881  -23.706 22.054  1.00 23.58  ? 259 PHE A CD2 1 
ATOM   1927  C  CE1 . PHE A 1 280 ? -4.800  -22.676 23.580  1.00 21.94  ? 259 PHE A CE1 1 
ATOM   1928  C  CE2 . PHE A 1 280 ? -6.977  -22.407 22.663  1.00 22.20  ? 259 PHE A CE2 1 
ATOM   1929  C  CZ  . PHE A 1 280 ? -5.945  -21.912 23.376  1.00 20.09  ? 259 PHE A CZ  1 
ATOM   1930  N  N   . ALA A 1 281 ? -4.814  -28.125 19.474  1.00 17.94  ? 260 ALA A N   1 
ATOM   1931  C  CA  . ALA A 1 281 ? -4.647  -29.552 19.258  1.00 20.47  ? 260 ALA A CA  1 
ATOM   1932  C  C   . ALA A 1 281 ? -3.197  -29.868 18.910  1.00 21.49  ? 260 ALA A C   1 
ATOM   1933  O  O   . ALA A 1 281 ? -2.668  -30.908 19.303  1.00 21.18  ? 260 ALA A O   1 
ATOM   1934  C  CB  . ALA A 1 281 ? -5.570  -30.033 18.147  1.00 19.07  ? 260 ALA A CB  1 
ATOM   1935  N  N   . ALA A 1 282 ? -2.549  -28.993 18.142  1.00 18.83  ? 261 ALA A N   1 
ATOM   1936  C  CA  . ALA A 1 282 ? -1.134  -29.207 17.828  1.00 17.31  ? 261 ALA A CA  1 
ATOM   1937  C  C   . ALA A 1 282 ? -0.287  -29.160 19.090  1.00 20.51  ? 261 ALA A C   1 
ATOM   1938  O  O   . ALA A 1 282 ? 0.657   -29.947 19.249  1.00 21.11  ? 261 ALA A O   1 
ATOM   1939  C  CB  . ALA A 1 282 ? -0.649  -28.156 16.813  1.00 19.10  ? 261 ALA A CB  1 
ATOM   1940  N  N   . VAL A 1 283 ? -0.577  -28.208 19.974  1.00 20.31  ? 262 VAL A N   1 
ATOM   1941  C  CA  . VAL A 1 283 ? 0.115   -28.151 21.262  1.00 20.55  ? 262 VAL A CA  1 
ATOM   1942  C  C   . VAL A 1 283 ? -0.101  -29.453 22.023  1.00 19.07  ? 262 VAL A C   1 
ATOM   1943  O  O   . VAL A 1 283 ? 0.836   -30.044 22.574  1.00 22.44  ? 262 VAL A O   1 
ATOM   1944  C  CB  . VAL A 1 283 ? -0.395  -26.957 22.094  1.00 23.07  ? 262 VAL A CB  1 
ATOM   1945  C  CG1 . VAL A 1 283 ? 0.173   -27.038 23.516  1.00 24.70  ? 262 VAL A CG1 1 
ATOM   1946  C  CG2 . VAL A 1 283 ? -0.048  -25.622 21.408  1.00 23.22  ? 262 VAL A CG2 1 
ATOM   1947  N  N   . ALA A 1 284 ? -1.356  -29.899 22.082  1.00 18.88  ? 263 ALA A N   1 
ATOM   1948  C  CA  . ALA A 1 284 ? -1.670  -31.107 22.839  1.00 20.11  ? 263 ALA A CA  1 
ATOM   1949  C  C   . ALA A 1 284 ? -0.961  -32.326 22.257  1.00 19.90  ? 263 ALA A C   1 
ATOM   1950  O  O   . ALA A 1 284 ? -0.593  -33.250 23.001  1.00 20.19  ? 263 ALA A O   1 
ATOM   1951  C  CB  . ALA A 1 284 ? -3.196  -31.323 22.858  1.00 17.18  ? 263 ALA A CB  1 
ATOM   1952  N  N   . LEU A 1 285 ? -0.829  -32.387 20.921  1.00 20.11  ? 264 LEU A N   1 
ATOM   1953  C  CA  . LEU A 1 285 ? -0.115  -33.521 20.312  1.00 21.01  ? 264 LEU A CA  1 
ATOM   1954  C  C   . LEU A 1 285 ? 1.381   -33.497 20.652  1.00 24.00  ? 264 LEU A C   1 
ATOM   1955  O  O   . LEU A 1 285 ? 1.984   -34.545 20.890  1.00 22.74  ? 264 LEU A O   1 
ATOM   1956  C  CB  . LEU A 1 285 ? -0.309  -33.503 18.801  1.00 17.92  ? 264 LEU A CB  1 
ATOM   1957  C  CG  . LEU A 1 285 ? -1.703  -33.974 18.323  1.00 21.17  ? 264 LEU A CG  1 
ATOM   1958  C  CD1 . LEU A 1 285 ? -1.932  -33.603 16.833  1.00 21.01  ? 264 LEU A CD1 1 
ATOM   1959  C  CD2 . LEU A 1 285 ? -1.843  -35.512 18.491  1.00 17.41  ? 264 LEU A CD2 1 
ATOM   1960  N  N   . ALA A 1 286 ? 1.974   -32.305 20.717  1.00 23.15  ? 265 ALA A N   1 
ATOM   1961  C  CA  . ALA A 1 286 ? 3.352   -32.155 21.201  1.00 22.76  ? 265 ALA A CA  1 
ATOM   1962  C  C   . ALA A 1 286 ? 3.475   -32.608 22.641  1.00 22.68  ? 265 ALA A C   1 
ATOM   1963  O  O   . ALA A 1 286 ? 4.477   -33.217 23.035  1.00 23.66  ? 265 ALA A O   1 
ATOM   1964  C  CB  . ALA A 1 286 ? 3.778   -30.676 21.089  1.00 23.05  ? 265 ALA A CB  1 
ATOM   1965  N  N   . GLU A 1 287 ? 2.446   -32.358 23.440  1.00 21.35  ? 266 GLU A N   1 
ATOM   1966  C  CA  . GLU A 1 287 ? 2.506   -32.670 24.852  1.00 22.77  ? 266 GLU A CA  1 
ATOM   1967  C  C   . GLU A 1 287 ? 2.080   -34.090 25.175  1.00 26.20  ? 266 GLU A C   1 
ATOM   1968  O  O   . GLU A 1 287 ? 2.304   -34.527 26.298  1.00 22.93  ? 266 GLU A O   1 
ATOM   1969  C  CB  . GLU A 1 287 ? 1.632   -31.708 25.639  1.00 24.17  ? 266 GLU A CB  1 
ATOM   1970  C  CG  . GLU A 1 287 ? 2.156   -30.290 25.621  1.00 26.19  ? 266 GLU A CG  1 
ATOM   1971  C  CD  . GLU A 1 287 ? 1.228   -29.311 26.363  1.00 35.20  ? 266 GLU A CD  1 
ATOM   1972  O  OE1 . GLU A 1 287 ? 0.019   -29.613 26.519  1.00 36.64  ? 266 GLU A OE1 1 
ATOM   1973  O  OE2 . GLU A 1 287 ? 1.721   -28.237 26.770  1.00 41.39  ? 266 GLU A OE2 1 
ATOM   1974  N  N   . ASN A 1 288 ? 1.461   -34.815 24.242  1.00 20.66  ? 267 ASN A N   1 
ATOM   1975  C  CA  . ASN A 1 288 ? 0.908   -36.144 24.542  1.00 23.28  ? 267 ASN A CA  1 
ATOM   1976  C  C   . ASN A 1 288 ? 1.343   -37.145 23.480  1.00 22.14  ? 267 ASN A C   1 
ATOM   1977  O  O   . ASN A 1 288 ? 0.533   -37.615 22.675  1.00 21.34  ? 267 ASN A O   1 
ATOM   1978  C  CB  . ASN A 1 288 ? -0.620  -36.059 24.656  1.00 23.20  ? 267 ASN A CB  1 
ATOM   1979  C  CG  . ASN A 1 288 ? -1.057  -35.200 25.821  1.00 25.15  ? 267 ASN A CG  1 
ATOM   1980  O  OD1 . ASN A 1 288 ? -1.200  -35.687 26.965  1.00 24.83  ? 267 ASN A OD1 1 
ATOM   1981  N  ND2 . ASN A 1 288 ? -1.242  -33.908 25.563  1.00 22.02  ? 267 ASN A ND2 1 
ATOM   1982  N  N   . PRO A 1 289 ? 2.642   -37.481 23.434  1.00 21.39  ? 268 PRO A N   1 
ATOM   1983  C  CA  . PRO A 1 289 ? 3.134   -38.281 22.311  1.00 23.00  ? 268 PRO A CA  1 
ATOM   1984  C  C   . PRO A 1 289 ? 2.592   -39.701 22.307  1.00 19.11  ? 268 PRO A C   1 
ATOM   1985  O  O   . PRO A 1 289 ? 2.540   -40.331 21.238  1.00 22.47  ? 268 PRO A O   1 
ATOM   1986  C  CB  . PRO A 1 289 ? 4.666   -38.258 22.494  1.00 23.66  ? 268 PRO A CB  1 
ATOM   1987  C  CG  . PRO A 1 289 ? 4.905   -37.849 23.927  1.00 28.68  ? 268 PRO A CG  1 
ATOM   1988  C  CD  . PRO A 1 289 ? 3.724   -37.012 24.319  1.00 22.31  ? 268 PRO A CD  1 
ATOM   1989  N  N   . GLN A 1 290 ? 2.174   -40.227 23.448  1.00 20.91  ? 269 GLN A N   1 
ATOM   1990  C  CA  . GLN A 1 290 ? 1.585   -41.567 23.397  1.00 25.70  ? 269 GLN A CA  1 
ATOM   1991  C  C   . GLN A 1 290 ? 0.206   -41.553 22.736  1.00 23.38  ? 269 GLN A C   1 
ATOM   1992  O  O   . GLN A 1 290 ? -0.144  -42.484 22.007  1.00 22.71  ? 269 GLN A O   1 
ATOM   1993  C  CB  . GLN A 1 290 ? 1.492   -42.164 24.797  1.00 32.00  ? 269 GLN A CB  1 
ATOM   1994  C  CG  . GLN A 1 290 ? 0.856   -43.548 24.779  1.00 51.53  ? 269 GLN A CG  1 
ATOM   1995  C  CD  . GLN A 1 290 ? 1.153   -44.380 26.015  1.00 80.39  ? 269 GLN A CD  1 
ATOM   1996  O  OE1 . GLN A 1 290 ? 1.968   -44.001 26.867  1.00 80.39  ? 269 GLN A OE1 1 
ATOM   1997  N  NE2 . GLN A 1 290 ? 0.496   -45.534 26.112  1.00 76.34  ? 269 GLN A NE2 1 
ATOM   1998  N  N   . TRP A 1 291 ? -0.605  -40.526 23.005  1.00 22.28  ? 270 TRP A N   1 
ATOM   1999  C  CA  . TRP A 1 291 ? -1.860  -40.377 22.261  1.00 18.89  ? 270 TRP A CA  1 
ATOM   2000  C  C   . TRP A 1 291 ? -1.599  -40.187 20.785  1.00 18.64  ? 270 TRP A C   1 
ATOM   2001  O  O   . TRP A 1 291 ? -2.341  -40.692 19.937  1.00 21.15  ? 270 TRP A O   1 
ATOM   2002  C  CB  . TRP A 1 291 ? -2.666  -39.194 22.824  1.00 18.99  ? 270 TRP A CB  1 
ATOM   2003  C  CG  . TRP A 1 291 ? -3.432  -39.668 24.021  1.00 21.03  ? 270 TRP A CG  1 
ATOM   2004  C  CD1 . TRP A 1 291 ? -3.117  -39.495 25.335  1.00 22.84  ? 270 TRP A CD1 1 
ATOM   2005  C  CD2 . TRP A 1 291 ? -4.617  -40.481 23.986  1.00 25.25  ? 270 TRP A CD2 1 
ATOM   2006  N  NE1 . TRP A 1 291 ? -4.057  -40.136 26.131  1.00 24.85  ? 270 TRP A NE1 1 
ATOM   2007  C  CE2 . TRP A 1 291 ? -4.987  -40.737 25.320  1.00 23.36  ? 270 TRP A CE2 1 
ATOM   2008  C  CE3 . TRP A 1 291 ? -5.416  -40.986 22.949  1.00 26.70  ? 270 TRP A CE3 1 
ATOM   2009  C  CZ2 . TRP A 1 291 ? -6.126  -41.497 25.654  1.00 35.54  ? 270 TRP A CZ2 1 
ATOM   2010  C  CZ3 . TRP A 1 291 ? -6.559  -41.744 23.281  1.00 26.30  ? 270 TRP A CZ3 1 
ATOM   2011  C  CH2 . TRP A 1 291 ? -6.894  -41.990 24.619  1.00 29.60  ? 270 TRP A CH2 1 
ATOM   2012  N  N   . ARG A 1 292 ? -0.574  -39.419 20.447  1.00 19.99  ? 271 ARG A N   1 
ATOM   2013  C  CA  . ARG A 1 292 ? -0.264  -39.225 19.040  1.00 22.23  ? 271 ARG A CA  1 
ATOM   2014  C  C   . ARG A 1 292 ? 0.035   -40.555 18.342  1.00 22.08  ? 271 ARG A C   1 
ATOM   2015  O  O   . ARG A 1 292 ? -0.434  -40.806 17.213  1.00 20.29  ? 271 ARG A O   1 
ATOM   2016  C  CB  . ARG A 1 292 ? 0.909   -38.260 18.933  1.00 24.94  ? 271 ARG A CB  1 
ATOM   2017  C  CG  . ARG A 1 292 ? 1.254   -37.911 17.517  1.00 22.37  ? 271 ARG A CG  1 
ATOM   2018  C  CD  . ARG A 1 292 ? 2.320   -36.810 17.547  1.00 23.07  ? 271 ARG A CD  1 
ATOM   2019  N  NE  . ARG A 1 292 ? 2.633   -36.392 16.199  1.00 22.95  ? 271 ARG A NE  1 
ATOM   2020  C  CZ  . ARG A 1 292 ? 3.552   -35.482 15.902  1.00 31.95  ? 271 ARG A CZ  1 
ATOM   2021  N  NH1 . ARG A 1 292 ? 4.266   -34.882 16.853  1.00 25.89  ? 271 ARG A NH1 1 
ATOM   2022  N  NH2 . ARG A 1 292 ? 3.788   -35.201 14.617  1.00 25.00  ? 271 ARG A NH2 1 
ATOM   2023  N  N   . THR A 1 293 ? 0.823   -41.406 18.992  1.00 21.57  ? 272 THR A N   1 
ATOM   2024  C  CA  . THR A 1 293 ? 1.102   -42.735 18.467  1.00 20.63  ? 272 THR A CA  1 
ATOM   2025  C  C   . THR A 1 293 ? -0.173  -43.541 18.290  1.00 22.11  ? 272 THR A C   1 
ATOM   2026  O  O   . THR A 1 293 ? -0.370  -44.188 17.256  1.00 22.33  ? 272 THR A O   1 
ATOM   2027  C  CB  . THR A 1 293 ? 2.061   -43.457 19.406  1.00 27.70  ? 272 THR A CB  1 
ATOM   2028  O  OG1 . THR A 1 293 ? 3.259   -42.677 19.519  1.00 29.71  ? 272 THR A OG1 1 
ATOM   2029  C  CG2 . THR A 1 293 ? 2.366   -44.873 18.908  1.00 25.29  ? 272 THR A CG2 1 
ATOM   2030  N  N   . ARG A 1 294 ? -1.077  -43.482 19.274  1.00 23.11  ? 273 ARG A N   1 
ATOM   2031  C  CA  . ARG A 1 294 ? -2.316  -44.250 19.166  1.00 21.76  ? 273 ARG A CA  1 
ATOM   2032  C  C   . ARG A 1 294 ? -3.169  -43.766 17.999  1.00 23.72  ? 273 ARG A C   1 
ATOM   2033  O  O   . ARG A 1 294 ? -3.786  -44.581 17.306  1.00 23.48  ? 273 ARG A O   1 
ATOM   2034  C  CB  . ARG A 1 294 ? -3.117  -44.182 20.466  1.00 21.72  ? 273 ARG A CB  1 
ATOM   2035  C  CG  . ARG A 1 294 ? -2.395  -44.876 21.647  1.00 23.81  ? 273 ARG A CG  1 
ATOM   2036  C  CD  . ARG A 1 294 ? -3.146  -44.696 22.970  1.00 28.78  ? 273 ARG A CD  1 
ATOM   2037  N  NE  . ARG A 1 294 ? -4.468  -45.318 22.974  1.00 28.10  ? 273 ARG A NE  1 
ATOM   2038  C  CZ  . ARG A 1 294 ? -5.299  -45.275 24.007  1.00 28.83  ? 273 ARG A CZ  1 
ATOM   2039  N  NH1 . ARG A 1 294 ? -4.983  -44.624 25.116  1.00 32.56  ? 273 ARG A NH1 1 
ATOM   2040  N  NH2 . ARG A 1 294 ? -6.468  -45.903 23.924  1.00 31.39  ? 273 ARG A NH2 1 
ATOM   2041  N  N   . ILE A 1 295 ? -3.243  -42.443 17.780  1.00 20.00  ? 274 ILE A N   1 
ATOM   2042  C  CA  . ILE A 1 295 ? -3.964  -41.924 16.606  1.00 18.50  ? 274 ILE A CA  1 
ATOM   2043  C  C   . ILE A 1 295 ? -3.348  -42.448 15.302  1.00 22.20  ? 274 ILE A C   1 
ATOM   2044  O  O   . ILE A 1 295 ? -4.064  -42.895 14.393  1.00 21.93  ? 274 ILE A O   1 
ATOM   2045  C  CB  . ILE A 1 295 ? -4.010  -40.387 16.652  1.00 18.85  ? 274 ILE A CB  1 
ATOM   2046  C  CG1 . ILE A 1 295 ? -4.857  -39.939 17.863  1.00 17.80  ? 274 ILE A CG1 1 
ATOM   2047  C  CG2 . ILE A 1 295 ? -4.568  -39.826 15.363  1.00 22.87  ? 274 ILE A CG2 1 
ATOM   2048  C  CD1 . ILE A 1 295 ? -4.630  -38.467 18.298  1.00 22.28  ? 274 ILE A CD1 1 
ATOM   2049  N  N   . ASN A 1 296 ? -2.017  -42.396 15.184  1.00 19.36  ? 275 ASN A N   1 
ATOM   2050  C  CA  . ASN A 1 296 ? -1.386  -42.852 13.945  1.00 20.45  ? 275 ASN A CA  1 
ATOM   2051  C  C   . ASN A 1 296 ? -1.569  -44.351 13.717  1.00 23.46  ? 275 ASN A C   1 
ATOM   2052  O  O   . ASN A 1 296 ? -1.600  -44.803 12.567  1.00 26.37  ? 275 ASN A O   1 
ATOM   2053  C  CB  . ASN A 1 296 ? 0.106   -42.519 13.965  1.00 22.33  ? 275 ASN A CB  1 
ATOM   2054  C  CG  . ASN A 1 296 ? 0.369   -41.041 13.835  1.00 23.20  ? 275 ASN A CG  1 
ATOM   2055  O  OD1 . ASN A 1 296 ? -0.366  -40.334 13.152  1.00 22.84  ? 275 ASN A OD1 1 
ATOM   2056  N  ND2 . ASN A 1 296 ? 1.406   -40.567 14.499  1.00 20.81  ? 275 ASN A ND2 1 
ATOM   2057  N  N   . GLU A 1 297 ? -1.698  -45.140 14.778  1.00 23.43  ? 276 GLU A N   1 
ATOM   2058  C  CA  . GLU A 1 297 ? -1.816  -46.581 14.588  1.00 25.73  ? 276 GLU A CA  1 
ATOM   2059  C  C   . GLU A 1 297 ? -3.255  -47.030 14.438  1.00 32.05  ? 276 GLU A C   1 
ATOM   2060  O  O   . GLU A 1 297 ? -3.500  -48.208 14.155  1.00 30.50  ? 276 GLU A O   1 
ATOM   2061  C  CB  . GLU A 1 297 ? -1.131  -47.313 15.740  1.00 22.94  ? 276 GLU A CB  1 
ATOM   2062  C  CG  . GLU A 1 297 ? 0.391   -47.048 15.721  1.00 26.12  ? 276 GLU A CG  1 
ATOM   2063  C  CD  . GLU A 1 297 ? 1.183   -47.822 16.780  1.00 38.30  ? 276 GLU A CD  1 
ATOM   2064  O  OE1 . GLU A 1 297 ? 0.650   -48.770 17.379  1.00 44.43  ? 276 GLU A OE1 1 
ATOM   2065  O  OE2 . GLU A 1 297 ? 2.361   -47.465 17.009  1.00 47.72  ? 276 GLU A OE2 1 
ATOM   2066  N  N   . SER A 1 298 ? -4.213  -46.122 14.593  1.00 28.10  ? 277 SER A N   1 
ATOM   2067  C  CA  . SER A 1 298 ? -5.619  -46.502 14.611  1.00 28.05  ? 277 SER A CA  1 
ATOM   2068  C  C   . SER A 1 298 ? -6.186  -46.666 13.213  1.00 29.88  ? 277 SER A C   1 
ATOM   2069  O  O   . SER A 1 298 ? -5.876  -45.907 12.302  1.00 35.83  ? 277 SER A O   1 
ATOM   2070  C  CB  . SER A 1 298 ? -6.462  -45.446 15.332  1.00 28.11  ? 277 SER A CB  1 
ATOM   2071  O  OG  . SER A 1 298 ? -7.840  -45.814 15.336  1.00 33.43  ? 277 SER A OG  1 
ATOM   2072  N  N   . GLU A 1 299 ? -7.111  -47.605 13.094  1.00 34.01  ? 278 GLU A N   1 
ATOM   2073  C  CA  . GLU A 1 299 ? -7.916  -47.781 11.901  1.00 45.85  ? 278 GLU A CA  1 
ATOM   2074  C  C   . GLU A 1 299 ? -9.312  -47.194 12.046  1.00 40.61  ? 278 GLU A C   1 
ATOM   2075  O  O   . GLU A 1 299 ? -10.048 -47.131 11.056  1.00 40.69  ? 278 GLU A O   1 
ATOM   2076  C  CB  . GLU A 1 299 ? -8.038  -49.277 11.576  1.00 55.72  ? 278 GLU A CB  1 
ATOM   2077  C  CG  . GLU A 1 299 ? -6.697  -50.013 11.503  1.00 63.40  ? 278 GLU A CG  1 
ATOM   2078  C  CD  . GLU A 1 299 ? -6.090  -49.977 10.113  1.00 63.18  ? 278 GLU A CD  1 
ATOM   2079  O  OE1 . GLU A 1 299 ? -6.851  -50.160 9.133   1.00 75.65  ? 278 GLU A OE1 1 
ATOM   2080  O  OE2 . GLU A 1 299 ? -4.860  -49.771 9.998   1.00 66.64  ? 278 GLU A OE2 1 
ATOM   2081  N  N   . THR A 1 300 ? -9.700  -46.770 13.248  1.00 28.58  ? 279 THR A N   1 
ATOM   2082  C  CA  . THR A 1 300 ? -11.104 -46.479 13.513  1.00 24.20  ? 279 THR A CA  1 
ATOM   2083  C  C   . THR A 1 300 ? -11.451 -45.002 13.569  1.00 32.32  ? 279 THR A C   1 
ATOM   2084  O  O   . THR A 1 300 ? -12.638 -44.674 13.534  1.00 28.01  ? 279 THR A O   1 
ATOM   2085  C  CB  . THR A 1 300 ? -11.519 -47.085 14.849  1.00 29.13  ? 279 THR A CB  1 
ATOM   2086  O  OG1 . THR A 1 300 ? -10.818 -46.392 15.897  1.00 27.81  ? 279 THR A OG1 1 
ATOM   2087  C  CG2 . THR A 1 300 ? -11.185 -48.598 14.894  1.00 32.48  ? 279 THR A CG2 1 
ATOM   2088  N  N   . GLY A 1 301 ? -10.470 -44.118 13.711  1.00 25.42  ? 280 GLY A N   1 
ATOM   2089  C  CA  . GLY A 1 301 ? -10.774 -42.744 14.034  1.00 26.26  ? 280 GLY A CA  1 
ATOM   2090  C  C   . GLY A 1 301 ? -11.291 -42.484 15.440  1.00 24.21  ? 280 GLY A C   1 
ATOM   2091  O  O   . GLY A 1 301 ? -11.547 -41.322 15.770  1.00 21.62  ? 280 GLY A O   1 
ATOM   2092  N  N   . ARG A 1 302 ? -11.411 -43.501 16.302  1.00 22.11  ? 281 ARG A N   1 
ATOM   2093  C  CA  . ARG A 1 302 ? -11.974 -43.260 17.635  1.00 20.96  ? 281 ARG A CA  1 
ATOM   2094  C  C   . ARG A 1 302 ? -11.041 -42.434 18.513  1.00 22.83  ? 281 ARG A C   1 
ATOM   2095  O  O   . ARG A 1 302 ? -11.511 -41.609 19.306  1.00 20.45  ? 281 ARG A O   1 
ATOM   2096  C  CB  . ARG A 1 302 ? -12.280 -44.581 18.361  1.00 23.76  ? 281 ARG A CB  1 
ATOM   2097  C  CG  . ARG A 1 302 ? -13.466 -45.343 17.798  1.00 38.69  ? 281 ARG A CG  1 
ATOM   2098  C  CD  . ARG A 1 302 ? -14.837 -44.718 18.111  1.00 42.44  ? 281 ARG A CD  1 
ATOM   2099  N  NE  . ARG A 1 302 ? -15.186 -44.827 19.525  1.00 38.13  ? 281 ARG A NE  1 
ATOM   2100  C  CZ  . ARG A 1 302 ? -15.682 -45.925 20.094  1.00 39.99  ? 281 ARG A CZ  1 
ATOM   2101  N  NH1 . ARG A 1 302 ? -15.960 -47.017 19.386  1.00 32.88  ? 281 ARG A NH1 1 
ATOM   2102  N  NH2 . ARG A 1 302 ? -15.914 -45.925 21.401  1.00 29.23  ? 281 ARG A NH2 1 
ATOM   2103  N  N   . GLU A 1 303 ? -9.727  -42.688 18.442  1.00 22.20  ? 282 GLU A N   1 
ATOM   2104  C  CA  . GLU A 1 303 ? -8.789  -41.927 19.274  1.00 21.32  ? 282 GLU A CA  1 
ATOM   2105  C  C   . GLU A 1 303 ? -8.728  -40.468 18.838  1.00 18.40  ? 282 GLU A C   1 
ATOM   2106  O  O   . GLU A 1 303 ? -8.617  -39.564 19.684  1.00 22.49  ? 282 GLU A O   1 
ATOM   2107  C  CB  . GLU A 1 303 ? -7.388  -42.547 19.217  1.00 22.42  ? 282 GLU A CB  1 
ATOM   2108  C  CG  . GLU A 1 303 ? -7.285  -44.002 19.792  1.00 23.94  ? 282 GLU A CG  1 
ATOM   2109  C  CD  . GLU A 1 303 ? -7.842  -45.096 18.847  1.00 33.85  ? 282 GLU A CD  1 
ATOM   2110  O  OE1 . GLU A 1 303 ? -8.286  -44.795 17.710  1.00 28.48  ? 282 GLU A OE1 1 
ATOM   2111  O  OE2 . GLU A 1 303 ? -7.822  -46.283 19.254  1.00 35.47  ? 282 GLU A OE2 1 
ATOM   2112  N  N   . ALA A 1 304 ? -8.746  -40.226 17.527  1.00 20.97  ? 283 ALA A N   1 
ATOM   2113  C  CA  . ALA A 1 304 ? -8.702  -38.849 17.048  1.00 22.75  ? 283 ALA A CA  1 
ATOM   2114  C  C   . ALA A 1 304 ? -9.946  -38.088 17.487  1.00 18.22  ? 283 ALA A C   1 
ATOM   2115  O  O   . ALA A 1 304 ? -9.869  -36.902 17.837  1.00 20.26  ? 283 ALA A O   1 
ATOM   2116  C  CB  . ALA A 1 304 ? -8.569  -38.817 15.532  1.00 22.27  ? 283 ALA A CB  1 
ATOM   2117  N  N   . PHE A 1 305 ? -11.092 -38.753 17.468  1.00 17.33  ? 284 PHE A N   1 
ATOM   2118  C  CA  . PHE A 1 305 ? -12.337 -38.125 17.932  1.00 20.28  ? 284 PHE A CA  1 
ATOM   2119  C  C   . PHE A 1 305 ? -12.243 -37.785 19.406  1.00 19.34  ? 284 PHE A C   1 
ATOM   2120  O  O   . PHE A 1 305 ? -12.577 -36.666 19.825  1.00 18.99  ? 284 PHE A O   1 
ATOM   2121  C  CB  . PHE A 1 305 ? -13.521 -39.091 17.659  1.00 22.17  ? 284 PHE A CB  1 
ATOM   2122  C  CG  . PHE A 1 305 ? -14.830 -38.739 18.350  1.00 24.32  ? 284 PHE A CG  1 
ATOM   2123  C  CD1 . PHE A 1 305 ? -15.750 -37.898 17.724  1.00 30.27  ? 284 PHE A CD1 1 
ATOM   2124  C  CD2 . PHE A 1 305 ? -15.157 -39.292 19.591  1.00 29.72  ? 284 PHE A CD2 1 
ATOM   2125  C  CE1 . PHE A 1 305 ? -16.997 -37.590 18.329  1.00 26.05  ? 284 PHE A CE1 1 
ATOM   2126  C  CE2 . PHE A 1 305 ? -16.389 -38.993 20.213  1.00 32.59  ? 284 PHE A CE2 1 
ATOM   2127  C  CZ  . PHE A 1 305 ? -17.312 -38.141 19.568  1.00 25.43  ? 284 PHE A CZ  1 
ATOM   2128  N  N   . ALA A 1 306 ? -11.800 -38.752 20.221  1.00 19.28  ? 285 ALA A N   1 
ATOM   2129  C  CA  . ALA A 1 306 ? -11.728 -38.519 21.656  1.00 18.56  ? 285 ALA A CA  1 
ATOM   2130  C  C   . ALA A 1 306 ? -10.737 -37.409 21.970  1.00 19.95  ? 285 ALA A C   1 
ATOM   2131  O  O   . ALA A 1 306 ? -10.952 -36.609 22.883  1.00 19.14  ? 285 ALA A O   1 
ATOM   2132  C  CB  . ALA A 1 306 ? -11.315 -39.806 22.399  1.00 17.73  ? 285 ALA A CB  1 
ATOM   2133  N  N   . PHE A 1 307 ? -9.615  -37.399 21.253  1.00 17.80  ? 286 PHE A N   1 
ATOM   2134  C  CA  . PHE A 1 307 ? -8.613  -36.351 21.403  1.00 18.11  ? 286 PHE A CA  1 
ATOM   2135  C  C   . PHE A 1 307 ? -9.185  -34.978 21.043  1.00 18.06  ? 286 PHE A C   1 
ATOM   2136  O  O   . PHE A 1 307 ? -8.975  -33.991 21.774  1.00 17.80  ? 286 PHE A O   1 
ATOM   2137  C  CB  . PHE A 1 307 ? -7.414  -36.703 20.526  1.00 19.25  ? 286 PHE A CB  1 
ATOM   2138  C  CG  . PHE A 1 307 ? -6.163  -35.911 20.843  1.00 20.69  ? 286 PHE A CG  1 
ATOM   2139  C  CD1 . PHE A 1 307 ? -5.966  -34.640 20.304  1.00 19.07  ? 286 PHE A CD1 1 
ATOM   2140  C  CD2 . PHE A 1 307 ? -5.159  -36.468 21.630  1.00 20.21  ? 286 PHE A CD2 1 
ATOM   2141  C  CE1 . PHE A 1 307 ? -4.771  -33.909 20.609  1.00 17.92  ? 286 PHE A CE1 1 
ATOM   2142  C  CE2 . PHE A 1 307 ? -3.986  -35.779 21.913  1.00 22.91  ? 286 PHE A CE2 1 
ATOM   2143  C  CZ  . PHE A 1 307 ? -3.788  -34.488 21.401  1.00 19.50  ? 286 PHE A CZ  1 
ATOM   2144  N  N   . ALA A 1 308 ? -9.932  -34.901 19.931  1.00 17.51  ? 287 ALA A N   1 
ATOM   2145  C  CA  . ALA A 1 308 ? -10.529 -33.623 19.546  1.00 18.10  ? 287 ALA A CA  1 
ATOM   2146  C  C   . ALA A 1 308 ? -11.517 -33.147 20.608  1.00 19.00  ? 287 ALA A C   1 
ATOM   2147  O  O   . ALA A 1 308 ? -11.583 -31.948 20.916  1.00 18.67  ? 287 ALA A O   1 
ATOM   2148  C  CB  . ALA A 1 308 ? -11.197 -33.759 18.172  1.00 20.14  ? 287 ALA A CB  1 
ATOM   2149  N  N   . GLN A 1 309 ? -12.303 -34.071 21.180  1.00 20.82  ? 288 GLN A N   1 
ATOM   2150  C  CA  . GLN A 1 309 ? -13.261 -33.675 22.225  1.00 19.45  ? 288 GLN A CA  1 
ATOM   2151  C  C   . GLN A 1 309 ? -12.547 -33.177 23.472  1.00 17.65  ? 288 GLN A C   1 
ATOM   2152  O  O   . GLN A 1 309 ? -12.968 -32.187 24.098  1.00 21.03  ? 288 GLN A O   1 
ATOM   2153  C  CB  . GLN A 1 309 ? -14.193 -34.852 22.573  1.00 19.00  ? 288 GLN A CB  1 
ATOM   2154  C  CG  . GLN A 1 309 ? -15.047 -35.273 21.364  1.00 20.76  ? 288 GLN A CG  1 
ATOM   2155  C  CD  . GLN A 1 309 ? -16.198 -34.299 21.090  1.00 22.50  ? 288 GLN A CD  1 
ATOM   2156  O  OE1 . GLN A 1 309 ? -16.065 -33.089 21.240  1.00 22.47  ? 288 GLN A OE1 1 
ATOM   2157  N  NE2 . GLN A 1 309 ? -17.344 -34.841 20.698  1.00 23.58  ? 288 GLN A NE2 1 
ATOM   2158  N  N   . GLU A 1 310 ? -11.452 -33.822 23.840  1.00 16.73  ? 289 GLU A N   1 
ATOM   2159  C  CA  . GLU A 1 310 ? -10.796 -33.381 25.061  1.00 18.74  ? 289 GLU A CA  1 
ATOM   2160  C  C   . GLU A 1 310 ? -9.980  -32.121 24.819  1.00 18.51  ? 289 GLU A C   1 
ATOM   2161  O  O   . GLU A 1 310 ? -9.723  -31.370 25.774  1.00 22.11  ? 289 GLU A O   1 
ATOM   2162  C  CB  . GLU A 1 310 ? -9.979  -34.554 25.657  1.00 24.46  ? 289 GLU A CB  1 
ATOM   2163  C  CG  . GLU A 1 310 ? -9.017  -34.254 26.855  1.00 19.13  ? 289 GLU A CG  1 
ATOM   2164  C  CD  . GLU A 1 310 ? -9.751  -34.014 28.183  1.00 23.87  ? 289 GLU A CD  1 
ATOM   2165  O  OE1 . GLU A 1 310 ? -10.954 -33.654 28.178  1.00 31.00  ? 289 GLU A OE1 1 
ATOM   2166  O  OE2 . GLU A 1 310 ? -9.153  -34.230 29.248  1.00 22.95  ? 289 GLU A OE2 1 
ATOM   2167  N  N   . VAL A 1 311 ? -9.617  -31.813 23.567  1.00 19.07  ? 290 VAL A N   1 
ATOM   2168  C  CA  . VAL A 1 311 ? -9.141  -30.453 23.281  1.00 16.79  ? 290 VAL A CA  1 
ATOM   2169  C  C   . VAL A 1 311 ? -10.243 -29.422 23.567  1.00 17.16  ? 290 VAL A C   1 
ATOM   2170  O  O   . VAL A 1 311 ? -9.997  -28.365 24.163  1.00 18.38  ? 290 VAL A O   1 
ATOM   2171  C  CB  . VAL A 1 311 ? -8.638  -30.372 21.830  1.00 19.53  ? 290 VAL A CB  1 
ATOM   2172  C  CG1 . VAL A 1 311 ? -8.420  -28.905 21.353  1.00 19.14  ? 290 VAL A CG1 1 
ATOM   2173  C  CG2 . VAL A 1 311 ? -7.291  -31.152 21.718  1.00 17.00  ? 290 VAL A CG2 1 
ATOM   2174  N  N   . ARG A 1 312 ? -11.465 -29.714 23.146  1.00 15.79  ? 291 ARG A N   1 
ATOM   2175  C  CA  . ARG A 1 312 ? -12.546 -28.754 23.343  1.00 17.42  ? 291 ARG A CA  1 
ATOM   2176  C  C   . ARG A 1 312 ? -12.898 -28.619 24.815  1.00 21.16  ? 291 ARG A C   1 
ATOM   2177  O  O   . ARG A 1 312 ? -13.355 -27.550 25.249  1.00 19.47  ? 291 ARG A O   1 
ATOM   2178  C  CB  . ARG A 1 312 ? -13.789 -29.165 22.545  1.00 19.05  ? 291 ARG A CB  1 
ATOM   2179  C  CG  . ARG A 1 312 ? -13.573 -29.165 21.000  1.00 18.68  ? 291 ARG A CG  1 
ATOM   2180  C  CD  . ARG A 1 312 ? -14.926 -29.019 20.239  1.00 21.84  ? 291 ARG A CD  1 
ATOM   2181  N  NE  . ARG A 1 312 ? -15.841 -30.094 20.619  1.00 22.09  ? 291 ARG A NE  1 
ATOM   2182  C  CZ  . ARG A 1 312 ? -17.155 -29.970 20.779  1.00 24.92  ? 291 ARG A CZ  1 
ATOM   2183  N  NH1 . ARG A 1 312 ? -17.787 -28.826 20.543  1.00 21.61  ? 291 ARG A NH1 1 
ATOM   2184  N  NH2 . ARG A 1 312 ? -17.853 -31.009 21.247  1.00 22.54  ? 291 ARG A NH2 1 
ATOM   2185  N  N   . ARG A 1 313 ? -12.758 -29.709 25.581  1.00 18.20  ? 292 ARG A N   1 
ATOM   2186  C  CA  . ARG A 1 313 ? -13.022 -29.627 27.015  1.00 18.10  ? 292 ARG A CA  1 
ATOM   2187  C  C   . ARG A 1 313 ? -11.938 -28.834 27.735  1.00 24.31  ? 292 ARG A C   1 
ATOM   2188  O  O   . ARG A 1 313 ? -12.223 -28.051 28.639  1.00 25.10  ? 292 ARG A O   1 
ATOM   2189  C  CB  . ARG A 1 313 ? -13.093 -31.019 27.651  1.00 23.18  ? 292 ARG A CB  1 
ATOM   2190  C  CG  . ARG A 1 313 ? -13.620 -30.846 29.088  1.00 27.73  ? 292 ARG A CG  1 
ATOM   2191  C  CD  . ARG A 1 313 ? -13.250 -31.875 30.078  1.00 25.55  ? 292 ARG A CD  1 
ATOM   2192  N  NE  . ARG A 1 313 ? -11.804 -32.091 30.186  1.00 20.60  ? 292 ARG A NE  1 
ATOM   2193  C  CZ  . ARG A 1 313 ? -11.046 -31.642 31.174  1.00 22.65  ? 292 ARG A CZ  1 
ATOM   2194  N  NH1 . ARG A 1 313 ? -11.530 -30.817 32.112  1.00 20.54  ? 292 ARG A NH1 1 
ATOM   2195  N  NH2 . ARG A 1 313 ? -9.774  -32.044 31.241  1.00 18.10  ? 292 ARG A NH2 1 
ATOM   2196  N  N   . PHE A 1 314 ? -10.683 -29.078 27.391  1.00 20.91  ? 293 PHE A N   1 
ATOM   2197  C  CA  . PHE A 1 314 ? -9.572  -28.647 28.223  1.00 19.49  ? 293 PHE A CA  1 
ATOM   2198  C  C   . PHE A 1 314 ? -9.117  -27.214 27.950  1.00 19.97  ? 293 PHE A C   1 
ATOM   2199  O  O   . PHE A 1 314 ? -8.809  -26.467 28.894  1.00 20.64  ? 293 PHE A O   1 
ATOM   2200  C  CB  . PHE A 1 314 ? -8.403  -29.596 27.979  1.00 18.94  ? 293 PHE A CB  1 
ATOM   2201  C  CG  . PHE A 1 314 ? -7.197  -29.277 28.816  1.00 21.23  ? 293 PHE A CG  1 
ATOM   2202  C  CD1 . PHE A 1 314 ? -7.121  -29.749 30.117  1.00 22.24  ? 293 PHE A CD1 1 
ATOM   2203  C  CD2 . PHE A 1 314 ? -6.133  -28.571 28.284  1.00 21.71  ? 293 PHE A CD2 1 
ATOM   2204  C  CE1 . PHE A 1 314 ? -5.987  -29.500 30.910  1.00 28.46  ? 293 PHE A CE1 1 
ATOM   2205  C  CE2 . PHE A 1 314 ? -4.975  -28.333 29.044  1.00 24.88  ? 293 PHE A CE2 1 
ATOM   2206  C  CZ  . PHE A 1 314 ? -4.916  -28.789 30.371  1.00 25.49  ? 293 PHE A CZ  1 
ATOM   2207  N  N   . TYR A 1 315 ? -9.034  -26.835 26.676  1.00 18.48  ? 294 TYR A N   1 
ATOM   2208  C  CA  . TYR A 1 315 ? -8.409  -25.562 26.330  1.00 19.00  ? 294 TYR A CA  1 
ATOM   2209  C  C   . TYR A 1 315 ? -9.424  -24.410 26.348  1.00 20.58  ? 294 TYR A C   1 
ATOM   2210  O  O   . TYR A 1 315 ? -10.604 -24.603 26.066  1.00 22.62  ? 294 TYR A O   1 
ATOM   2211  C  CB  . TYR A 1 315 ? -7.739  -25.663 24.968  1.00 18.43  ? 294 TYR A CB  1 
ATOM   2212  C  CG  . TYR A 1 315 ? -6.489  -26.531 25.060  1.00 19.06  ? 294 TYR A CG  1 
ATOM   2213  C  CD1 . TYR A 1 315 ? -5.296  -26.003 25.583  1.00 20.73  ? 294 TYR A CD1 1 
ATOM   2214  C  CD2 . TYR A 1 315 ? -6.522  -27.871 24.693  1.00 22.13  ? 294 TYR A CD2 1 
ATOM   2215  C  CE1 . TYR A 1 315 ? -4.151  -26.808 25.716  1.00 23.68  ? 294 TYR A CE1 1 
ATOM   2216  C  CE2 . TYR A 1 315 ? -5.380  -28.684 24.825  1.00 18.11  ? 294 TYR A CE2 1 
ATOM   2217  C  CZ  . TYR A 1 315 ? -4.215  -28.137 25.300  1.00 22.29  ? 294 TYR A CZ  1 
ATOM   2218  O  OH  . TYR A 1 315 ? -3.103  -28.911 25.425  1.00 26.70  ? 294 TYR A OH  1 
ATOM   2219  N  N   . PRO A 1 316 ? -8.973  -23.193 26.672  1.00 20.73  ? 295 PRO A N   1 
ATOM   2220  C  CA  . PRO A 1 316 ? -9.902  -22.063 26.804  1.00 21.54  ? 295 PRO A CA  1 
ATOM   2221  C  C   . PRO A 1 316 ? -10.288 -21.502 25.432  1.00 23.26  ? 295 PRO A C   1 
ATOM   2222  O  O   . PRO A 1 316 ? -9.444  -21.251 24.567  1.00 23.65  ? 295 PRO A O   1 
ATOM   2223  C  CB  . PRO A 1 316 ? -9.100  -21.044 27.628  1.00 20.03  ? 295 PRO A CB  1 
ATOM   2224  C  CG  . PRO A 1 316 ? -7.685  -21.249 27.088  1.00 18.80  ? 295 PRO A CG  1 
ATOM   2225  C  CD  . PRO A 1 316 ? -7.577  -22.801 26.944  1.00 19.93  ? 295 PRO A CD  1 
ATOM   2226  N  N   . PHE A 1 317 ? -11.587 -21.339 25.222  1.00 22.04  ? 296 PHE A N   1 
ATOM   2227  C  CA  . PHE A 1 317 ? -12.045 -20.747 23.983  1.00 21.19  ? 296 PHE A CA  1 
ATOM   2228  C  C   . PHE A 1 317 ? -13.164 -19.796 24.365  1.00 22.62  ? 296 PHE A C   1 
ATOM   2229  O  O   . PHE A 1 317 ? -12.973 -18.573 24.386  1.00 20.24  ? 296 PHE A O   1 
ATOM   2230  C  CB  . PHE A 1 317 ? -12.480 -21.847 22.989  1.00 19.81  ? 296 PHE A CB  1 
ATOM   2231  C  CG  . PHE A 1 317 ? -12.661 -21.348 21.563  1.00 21.40  ? 296 PHE A CG  1 
ATOM   2232  C  CD1 . PHE A 1 317 ? -13.280 -20.142 21.304  1.00 24.75  ? 296 PHE A CD1 1 
ATOM   2233  C  CD2 . PHE A 1 317 ? -12.219 -22.119 20.486  1.00 26.65  ? 296 PHE A CD2 1 
ATOM   2234  C  CE1 . PHE A 1 317 ? -13.463 -19.674 19.989  1.00 28.06  ? 296 PHE A CE1 1 
ATOM   2235  C  CE2 . PHE A 1 317 ? -12.412 -21.688 19.193  1.00 29.42  ? 296 PHE A CE2 1 
ATOM   2236  C  CZ  . PHE A 1 317 ? -13.021 -20.450 18.935  1.00 23.95  ? 296 PHE A CZ  1 
ATOM   2237  N  N   . VAL A 1 318 ? -14.337 -20.329 24.701  1.00 20.30  ? 297 VAL A N   1 
ATOM   2238  C  CA  . VAL A 1 318 ? -15.386 -19.462 25.238  1.00 20.10  ? 297 VAL A CA  1 
ATOM   2239  C  C   . VAL A 1 318 ? -15.128 -19.234 26.726  1.00 20.61  ? 297 VAL A C   1 
ATOM   2240  O  O   . VAL A 1 318 ? -15.101 -20.199 27.503  1.00 25.69  ? 297 VAL A O   1 
ATOM   2241  C  CB  . VAL A 1 318 ? -16.779 -20.084 25.003  1.00 20.88  ? 297 VAL A CB  1 
ATOM   2242  C  CG1 . VAL A 1 318 ? -17.887 -19.139 25.490  1.00 22.84  ? 297 VAL A CG1 1 
ATOM   2243  C  CG2 . VAL A 1 318 ? -16.942 -20.437 23.511  1.00 24.23  ? 297 VAL A CG2 1 
ATOM   2244  N  N   . PRO A 1 319 ? -14.930 -17.993 27.183  1.00 22.47  ? 298 PRO A N   1 
ATOM   2245  C  CA  . PRO A 1 319 ? -14.697 -17.799 28.631  1.00 23.43  ? 298 PRO A CA  1 
ATOM   2246  C  C   . PRO A 1 319 ? -15.970 -17.991 29.441  1.00 27.59  ? 298 PRO A C   1 
ATOM   2247  O  O   . PRO A 1 319 ? -15.990 -18.688 30.480  1.00 25.43  ? 298 PRO A O   1 
ATOM   2248  C  CB  . PRO A 1 319 ? -14.164 -16.359 28.719  1.00 24.82  ? 298 PRO A CB  1 
ATOM   2249  C  CG  . PRO A 1 319 ? -14.702 -15.660 27.473  1.00 28.05  ? 298 PRO A CG  1 
ATOM   2250  C  CD  . PRO A 1 319 ? -14.831 -16.754 26.390  1.00 21.42  ? 298 PRO A CD  1 
ATOM   2251  N  N   . MET A 1 320 ? -17.048 -17.417 28.941  1.00 22.19  ? 299 MET A N   1 
ATOM   2252  C  CA  . MET A 1 320 ? -18.319 -17.271 29.637  1.00 24.48  ? 299 MET A CA  1 
ATOM   2253  C  C   . MET A 1 320 ? -19.299 -16.737 28.607  1.00 24.45  ? 299 MET A C   1 
ATOM   2254  O  O   . MET A 1 320 ? -18.894 -16.331 27.516  1.00 22.47  ? 299 MET A O   1 
ATOM   2255  C  CB  . MET A 1 320 ? -18.194 -16.323 30.823  1.00 22.75  ? 299 MET A CB  1 
ATOM   2256  C  CG  . MET A 1 320 ? -17.905 -14.890 30.390  1.00 23.31  ? 299 MET A CG  1 
ATOM   2257  S  SD  . MET A 1 320 ? -17.339 -13.897 31.823  1.00 34.27  ? 299 MET A SD  1 
ATOM   2258  C  CE  . MET A 1 320 ? -15.558 -14.088 31.725  1.00 33.27  ? 299 MET A CE  1 
ATOM   2259  N  N   . PHE A 1 321 ? -20.586 -16.732 28.960  1.00 21.59  ? 300 PHE A N   1 
ATOM   2260  C  CA  . PHE A 1 321 ? -21.582 -16.264 27.994  1.00 19.97  ? 300 PHE A CA  1 
ATOM   2261  C  C   . PHE A 1 321 ? -22.761 -15.673 28.755  1.00 19.81  ? 300 PHE A C   1 
ATOM   2262  O  O   . PHE A 1 321 ? -23.094 -16.144 29.854  1.00 22.39  ? 300 PHE A O   1 
ATOM   2263  C  CB  . PHE A 1 321 ? -22.075 -17.405 27.065  1.00 20.64  ? 300 PHE A CB  1 
ATOM   2264  C  CG  . PHE A 1 321 ? -22.323 -16.963 25.641  1.00 20.15  ? 300 PHE A CG  1 
ATOM   2265  C  CD1 . PHE A 1 321 ? -21.257 -16.684 24.774  1.00 19.58  ? 300 PHE A CD1 1 
ATOM   2266  C  CD2 . PHE A 1 321 ? -23.608 -16.809 25.166  1.00 22.18  ? 300 PHE A CD2 1 
ATOM   2267  C  CE1 . PHE A 1 321 ? -21.488 -16.263 23.449  1.00 23.48  ? 300 PHE A CE1 1 
ATOM   2268  C  CE2 . PHE A 1 321 ? -23.841 -16.403 23.856  1.00 21.11  ? 300 PHE A CE2 1 
ATOM   2269  C  CZ  . PHE A 1 321 ? -22.792 -16.131 22.997  1.00 23.18  ? 300 PHE A CZ  1 
ATOM   2270  N  N   . PRO A 1 322 ? -23.407 -14.620 28.202  1.00 22.43  ? 301 PRO A N   1 
ATOM   2271  C  CA  . PRO A 1 322 ? -24.376 -13.875 29.001  1.00 17.65  ? 301 PRO A CA  1 
ATOM   2272  C  C   . PRO A 1 322 ? -25.817 -14.077 28.576  1.00 21.00  ? 301 PRO A C   1 
ATOM   2273  O  O   . PRO A 1 322 ? -26.098 -14.379 27.415  1.00 19.99  ? 301 PRO A O   1 
ATOM   2274  C  CB  . PRO A 1 322 ? -23.961 -12.408 28.758  1.00 24.28  ? 301 PRO A CB  1 
ATOM   2275  C  CG  . PRO A 1 322 ? -23.626 -12.405 27.283  1.00 23.83  ? 301 PRO A CG  1 
ATOM   2276  C  CD  . PRO A 1 322 ? -22.860 -13.781 27.107  1.00 21.50  ? 301 PRO A CD  1 
ATOM   2277  N  N   . ALA A 1 323 ? -26.716 -13.896 29.541  1.00 21.49  ? 302 ALA A N   1 
ATOM   2278  C  CA  . ALA A 1 323 ? -28.156 -13.842 29.347  1.00 19.45  ? 302 ALA A CA  1 
ATOM   2279  C  C   . ALA A 1 323 ? -28.670 -12.767 30.292  1.00 24.17  ? 302 ALA A C   1 
ATOM   2280  O  O   . ALA A 1 323 ? -27.936 -12.291 31.176  1.00 21.32  ? 302 ALA A O   1 
ATOM   2281  C  CB  . ALA A 1 323 ? -28.842 -15.202 29.653  1.00 21.47  ? 302 ALA A CB  1 
ATOM   2282  N  N   . LYS A 1 324 ? -29.938 -12.393 30.123  1.00 21.94  ? 303 LYS A N   1 
ATOM   2283  C  CA  . LYS A 1 324 ? -30.596 -11.429 31.010  1.00 22.69  ? 303 LYS A CA  1 
ATOM   2284  C  C   . LYS A 1 324 ? -31.888 -12.000 31.579  1.00 19.87  ? 303 LYS A C   1 
ATOM   2285  O  O   . LYS A 1 324 ? -32.631 -12.707 30.885  1.00 23.48  ? 303 LYS A O   1 
ATOM   2286  C  CB  . LYS A 1 324 ? -30.909 -10.111 30.256  1.00 24.47  ? 303 LYS A CB  1 
ATOM   2287  C  CG  . LYS A 1 324 ? -29.706 -9.244  30.033  1.00 30.74  ? 303 LYS A CG  1 
ATOM   2288  C  CD  . LYS A 1 324 ? -30.094 -7.971  29.281  1.00 35.88  ? 303 LYS A CD  1 
ATOM   2289  C  CE  . LYS A 1 324 ? -29.219 -6.808  29.694  1.00 44.11  ? 303 LYS A CE  1 
ATOM   2290  N  NZ  . LYS A 1 324 ? -29.907 -6.006  30.738  1.00 50.84  ? 303 LYS A NZ  1 
ATOM   2291  N  N   . ALA A 1 325 ? -32.170 -11.696 32.841  1.00 25.85  ? 304 ALA A N   1 
ATOM   2292  C  CA  . ALA A 1 325 ? -33.364 -12.230 33.478  1.00 23.71  ? 304 ALA A CA  1 
ATOM   2293  C  C   . ALA A 1 325 ? -34.586 -11.502 32.945  1.00 25.82  ? 304 ALA A C   1 
ATOM   2294  O  O   . ALA A 1 325 ? -34.593 -10.271 32.868  1.00 26.29  ? 304 ALA A O   1 
ATOM   2295  C  CB  . ALA A 1 325 ? -33.283 -12.086 34.991  1.00 23.80  ? 304 ALA A CB  1 
ATOM   2296  N  N   . THR A 1 326 ? -35.621 -12.258 32.566  1.00 22.40  ? 305 THR A N   1 
ATOM   2297  C  CA  . THR A 1 326 ? -36.835 -11.626 32.049  1.00 28.99  ? 305 THR A CA  1 
ATOM   2298  C  C   . THR A 1 326 ? -37.825 -11.255 33.144  1.00 31.84  ? 305 THR A C   1 
ATOM   2299  O  O   . THR A 1 326 ? -38.797 -10.545 32.869  1.00 30.10  ? 305 THR A O   1 
ATOM   2300  C  CB  . THR A 1 326 ? -37.546 -12.538 31.057  1.00 29.10  ? 305 THR A CB  1 
ATOM   2301  O  OG1 . THR A 1 326 ? -37.975 -13.710 31.748  1.00 27.68  ? 305 THR A OG1 1 
ATOM   2302  C  CG2 . THR A 1 326 ? -36.617 -12.946 29.956  1.00 29.50  ? 305 THR A CG2 1 
ATOM   2303  N  N   . LYS A 1 327 ? -37.596 -11.716 34.361  1.00 25.12  ? 306 LYS A N   1 
ATOM   2304  C  CA  . LYS A 1 327 ? -38.466 -11.481 35.502  1.00 31.89  ? 306 LYS A CA  1 
ATOM   2305  C  C   . LYS A 1 327 ? -37.652 -11.762 36.751  1.00 34.03  ? 306 LYS A C   1 
ATOM   2306  O  O   . LYS A 1 327 ? -36.596 -12.400 36.684  1.00 32.13  ? 306 LYS A O   1 
ATOM   2307  C  CB  . LYS A 1 327 ? -39.705 -12.377 35.448  1.00 33.76  ? 306 LYS A CB  1 
ATOM   2308  C  CG  . LYS A 1 327 ? -39.386 -13.861 35.490  1.00 35.88  ? 306 LYS A CG  1 
ATOM   2309  C  CD  . LYS A 1 327 ? -40.651 -14.725 35.463  1.00 37.76  ? 306 LYS A CD  1 
ATOM   2310  C  CE  . LYS A 1 327 ? -41.179 -14.907 34.054  1.00 50.69  ? 306 LYS A CE  1 
ATOM   2311  N  NZ  . LYS A 1 327 ? -42.424 -15.731 34.017  1.00 63.50  ? 306 LYS A NZ  1 
ATOM   2312  N  N   . ASP A 1 328 ? -38.132 -11.265 37.891  1.00 26.02  ? 307 ASP A N   1 
ATOM   2313  C  CA  . ASP A 1 328 ? -37.431 -11.523 39.145  1.00 26.51  ? 307 ASP A CA  1 
ATOM   2314  C  C   . ASP A 1 328 ? -37.523 -13.009 39.472  1.00 31.92  ? 307 ASP A C   1 
ATOM   2315  O  O   . ASP A 1 328 ? -38.587 -13.621 39.359  1.00 31.19  ? 307 ASP A O   1 
ATOM   2316  C  CB  . ASP A 1 328 ? -38.026 -10.731 40.312  1.00 32.55  ? 307 ASP A CB  1 
ATOM   2317  C  CG  . ASP A 1 328 ? -37.888 -9.210  40.159  1.00 33.08  ? 307 ASP A CG  1 
ATOM   2318  O  OD1 . ASP A 1 328 ? -36.871 -8.695  39.624  1.00 30.61  ? 307 ASP A OD1 1 
ATOM   2319  O  OD2 . ASP A 1 328 ? -38.832 -8.519  40.613  1.00 34.34  ? 307 ASP A OD2 1 
ATOM   2320  N  N   . THR A 1 329 ? -36.409 -13.592 39.887  1.00 30.49  ? 308 THR A N   1 
ATOM   2321  C  CA  . THR A 1 329 ? -36.404 -15.016 40.224  1.00 29.31  ? 308 THR A CA  1 
ATOM   2322  C  C   . THR A 1 329 ? -35.311 -15.242 41.263  1.00 38.44  ? 308 THR A C   1 
ATOM   2323  O  O   . THR A 1 329 ? -34.812 -14.294 41.880  1.00 31.08  ? 308 THR A O   1 
ATOM   2324  C  CB  . THR A 1 329 ? -36.260 -15.850 38.932  1.00 35.42  ? 308 THR A CB  1 
ATOM   2325  O  OG1 . THR A 1 329 ? -36.383 -17.242 39.233  1.00 43.38  ? 308 THR A OG1 1 
ATOM   2326  C  CG2 . THR A 1 329 ? -34.912 -15.581 38.218  1.00 29.38  ? 308 THR A CG2 1 
ATOM   2327  N  N   . GLU A 1 330 ? -34.937 -16.499 41.481  1.00 37.60  ? 309 GLU A N   1 
ATOM   2328  C  CA  . GLU A 1 330 ? -34.002 -16.814 42.554  1.00 40.44  ? 309 GLU A CA  1 
ATOM   2329  C  C   . GLU A 1 330 ? -33.240 -18.078 42.187  1.00 35.27  ? 309 GLU A C   1 
ATOM   2330  O  O   . GLU A 1 330 ? -33.785 -18.973 41.542  1.00 38.51  ? 309 GLU A O   1 
ATOM   2331  C  CB  . GLU A 1 330 ? -34.723 -16.993 43.893  1.00 43.84  ? 309 GLU A CB  1 
ATOM   2332  C  CG  . GLU A 1 330 ? -33.783 -17.232 45.056  1.00 61.80  ? 309 GLU A CG  1 
ATOM   2333  C  CD  . GLU A 1 330 ? -34.358 -16.759 46.380  1.00 74.26  ? 309 GLU A CD  1 
ATOM   2334  O  OE1 . GLU A 1 330 ? -35.571 -16.463 46.425  1.00 94.83  ? 309 GLU A OE1 1 
ATOM   2335  O  OE2 . GLU A 1 330 ? -33.596 -16.676 47.370  1.00 71.13  ? 309 GLU A OE2 1 
ATOM   2336  N  N   . PHE A 1 331 ? -31.969 -18.134 42.575  1.00 34.72  ? 310 PHE A N   1 
ATOM   2337  C  CA  . PHE A 1 331 ? -31.102 -19.256 42.211  1.00 33.08  ? 310 PHE A CA  1 
ATOM   2338  C  C   . PHE A 1 331 ? -30.258 -19.603 43.418  1.00 31.17  ? 310 PHE A C   1 
ATOM   2339  O  O   . PHE A 1 331 ? -29.362 -18.827 43.785  1.00 32.60  ? 310 PHE A O   1 
ATOM   2340  C  CB  . PHE A 1 331 ? -30.200 -18.918 41.033  1.00 30.04  ? 310 PHE A CB  1 
ATOM   2341  C  CG  . PHE A 1 331 ? -29.288 -20.045 40.645  1.00 31.78  ? 310 PHE A CG  1 
ATOM   2342  C  CD1 . PHE A 1 331 ? -29.809 -21.197 40.084  1.00 39.87  ? 310 PHE A CD1 1 
ATOM   2343  C  CD2 . PHE A 1 331 ? -27.930 -19.946 40.827  1.00 34.39  ? 310 PHE A CD2 1 
ATOM   2344  C  CE1 . PHE A 1 331 ? -28.964 -22.248 39.713  1.00 33.43  ? 310 PHE A CE1 1 
ATOM   2345  C  CE2 . PHE A 1 331 ? -27.076 -20.989 40.464  1.00 37.00  ? 310 PHE A CE2 1 
ATOM   2346  C  CZ  . PHE A 1 331 ? -27.607 -22.137 39.899  1.00 28.28  ? 310 PHE A CZ  1 
ATOM   2347  N  N   . GLU A 1 332 ? -30.538 -20.763 44.012  1.00 33.00  ? 311 GLU A N   1 
ATOM   2348  C  CA  . GLU A 1 332 ? -29.813 -21.241 45.186  1.00 30.46  ? 311 GLU A CA  1 
ATOM   2349  C  C   . GLU A 1 332 ? -29.694 -20.147 46.246  1.00 37.76  ? 311 GLU A C   1 
ATOM   2350  O  O   . GLU A 1 332 ? -28.603 -19.802 46.694  1.00 41.02  ? 311 GLU A O   1 
ATOM   2351  C  CB  . GLU A 1 332 ? -28.445 -21.764 44.770  1.00 39.70  ? 311 GLU A CB  1 
ATOM   2352  C  CG  . GLU A 1 332 ? -28.592 -23.025 43.923  1.00 44.39  ? 311 GLU A CG  1 
ATOM   2353  C  CD  . GLU A 1 332 ? -27.296 -23.467 43.308  1.00 53.96  ? 311 GLU A CD  1 
ATOM   2354  O  OE1 . GLU A 1 332 ? -26.284 -22.762 43.507  1.00 54.60  ? 311 GLU A OE1 1 
ATOM   2355  O  OE2 . GLU A 1 332 ? -27.292 -24.519 42.624  1.00 42.23  ? 311 GLU A OE2 1 
ATOM   2356  N  N   . GLY A 1 333 ? -30.837 -19.560 46.609  1.00 43.54  ? 312 GLY A N   1 
ATOM   2357  C  CA  . GLY A 1 333 ? -30.878 -18.513 47.613  1.00 48.67  ? 312 GLY A CA  1 
ATOM   2358  C  C   . GLY A 1 333 ? -30.378 -17.155 47.173  1.00 47.03  ? 312 GLY A C   1 
ATOM   2359  O  O   . GLY A 1 333 ? -30.430 -16.208 47.965  1.00 51.87  ? 312 GLY A O   1 
ATOM   2360  N  N   . CYS A 1 334 ? -29.891 -17.024 45.979  1.00 41.49  ? 313 CYS A N   1 
ATOM   2361  C  CA  . CYS A 1 334 ? -29.435 -15.727 45.501  1.00 39.59  ? 313 CYS A CA  1 
ATOM   2362  C  C   . CYS A 1 334 ? -30.564 -15.060 44.716  1.00 47.43  ? 313 CYS A C   1 
ATOM   2363  O  O   . CYS A 1 334 ? -31.135 -15.686 43.819  1.00 30.32  ? 313 CYS A O   1 
ATOM   2364  C  CB  . CYS A 1 334 ? -28.197 -15.895 44.629  1.00 40.15  ? 313 CYS A CB  1 
ATOM   2365  S  SG  . CYS A 1 334 ? -27.648 -14.453 43.687  1.00 51.78  ? 313 CYS A SG  1 
ATOM   2366  N  N   . PRO A 1 335 ? -30.946 -13.825 45.030  1.00 38.14  ? 314 PRO A N   1 
ATOM   2367  C  CA  . PRO A 1 335 ? -31.997 -13.174 44.237  1.00 37.24  ? 314 PRO A CA  1 
ATOM   2368  C  C   . PRO A 1 335 ? -31.450 -12.795 42.867  1.00 29.86  ? 314 PRO A C   1 
ATOM   2369  O  O   . PRO A 1 335 ? -30.281 -12.430 42.719  1.00 33.83  ? 314 PRO A O   1 
ATOM   2370  C  CB  . PRO A 1 335 ? -32.372 -11.939 45.075  1.00 40.48  ? 314 PRO A CB  1 
ATOM   2371  C  CG  . PRO A 1 335 ? -31.082 -11.616 45.826  1.00 43.77  ? 314 PRO A CG  1 
ATOM   2372  C  CD  . PRO A 1 335 ? -30.446 -12.970 46.124  1.00 34.46  ? 314 PRO A CD  1 
ATOM   2373  N  N   . ILE A 1 336 ? -32.291 -12.953 41.851  1.00 27.68  ? 315 ILE A N   1 
ATOM   2374  C  CA  . ILE A 1 336 ? -31.967 -12.587 40.475  1.00 29.17  ? 315 ILE A CA  1 
ATOM   2375  C  C   . ILE A 1 336 ? -33.012 -11.570 40.037  1.00 28.06  ? 315 ILE A C   1 
ATOM   2376  O  O   . ILE A 1 336 ? -34.194 -11.908 39.946  1.00 27.70  ? 315 ILE A O   1 
ATOM   2377  C  CB  . ILE A 1 336 ? -31.981 -13.804 39.528  1.00 31.62  ? 315 ILE A CB  1 
ATOM   2378  C  CG1 . ILE A 1 336 ? -31.022 -14.913 40.007  1.00 32.68  ? 315 ILE A CG1 1 
ATOM   2379  C  CG2 . ILE A 1 336 ? -31.612 -13.369 38.148  1.00 27.53  ? 315 ILE A CG2 1 
ATOM   2380  C  CD1 . ILE A 1 336 ? -29.594 -14.598 39.840  1.00 35.29  ? 315 ILE A CD1 1 
ATOM   2381  N  N   . HIS A 1 337 ? -32.585 -10.343 39.771  1.00 25.24  ? 316 HIS A N   1 
ATOM   2382  C  CA  . HIS A 1 337 ? -33.516 -9.258  39.441  1.00 26.62  ? 316 HIS A CA  1 
ATOM   2383  C  C   . HIS A 1 337 ? -33.769 -9.158  37.942  1.00 25.79  ? 316 HIS A C   1 
ATOM   2384  O  O   . HIS A 1 337 ? -32.848 -9.262  37.140  1.00 23.60  ? 316 HIS A O   1 
ATOM   2385  C  CB  . HIS A 1 337 ? -32.969 -7.921  39.921  1.00 29.25  ? 316 HIS A CB  1 
ATOM   2386  C  CG  . HIS A 1 337 ? -32.665 -7.909  41.376  1.00 39.08  ? 316 HIS A CG  1 
ATOM   2387  N  ND1 . HIS A 1 337 ? -33.645 -8.046  42.336  1.00 47.84  ? 316 HIS A ND1 1 
ATOM   2388  C  CD2 . HIS A 1 337 ? -31.491 -7.805  42.042  1.00 45.98  ? 316 HIS A CD2 1 
ATOM   2389  C  CE1 . HIS A 1 337 ? -33.088 -8.010  43.533  1.00 49.57  ? 316 HIS A CE1 1 
ATOM   2390  N  NE2 . HIS A 1 337 ? -31.783 -7.857  43.382  1.00 46.53  ? 316 HIS A NE2 1 
ATOM   2391  N  N   . GLN A 1 338 ? -35.009 -8.841  37.585  1.00 23.24  ? 317 GLN A N   1 
ATOM   2392  C  CA  . GLN A 1 338 ? -35.350 -8.649  36.185  1.00 25.68  ? 317 GLN A CA  1 
ATOM   2393  C  C   . GLN A 1 338 ? -34.375 -7.676  35.552  1.00 24.89  ? 317 GLN A C   1 
ATOM   2394  O  O   . GLN A 1 338 ? -34.061 -6.624  36.123  1.00 27.20  ? 317 GLN A O   1 
ATOM   2395  C  CB  . GLN A 1 338 ? -36.803 -8.126  36.082  1.00 24.31  ? 317 GLN A CB  1 
ATOM   2396  C  CG  . GLN A 1 338 ? -37.282 -7.860  34.651  1.00 21.73  ? 317 GLN A CG  1 
ATOM   2397  C  CD  . GLN A 1 338 ? -38.782 -7.673  34.598  1.00 24.12  ? 317 GLN A CD  1 
ATOM   2398  O  OE1 . GLN A 1 338 ? -39.452 -7.765  35.625  1.00 28.44  ? 317 GLN A OE1 1 
ATOM   2399  N  NE2 . GLN A 1 338 ? -39.314 -7.396  33.414  1.00 25.88  ? 317 GLN A NE2 1 
ATOM   2400  N  N   . GLY A 1 339 ? -33.860 -8.041  34.390  1.00 25.08  ? 318 GLY A N   1 
ATOM   2401  C  CA  . GLY A 1 339 ? -32.938 -7.196  33.676  1.00 26.87  ? 318 GLY A CA  1 
ATOM   2402  C  C   . GLY A 1 339 ? -31.471 -7.408  34.017  1.00 28.61  ? 318 GLY A C   1 
ATOM   2403  O  O   . GLY A 1 339 ? -30.604 -6.978  33.250  1.00 26.82  ? 318 GLY A O   1 
ATOM   2404  N  N   . GLN A 1 340 ? -31.157 -8.031  35.147  1.00 22.60  ? 319 GLN A N   1 
ATOM   2405  C  CA  . GLN A 1 340 ? -29.742 -8.225  35.431  1.00 25.36  ? 319 GLN A CA  1 
ATOM   2406  C  C   . GLN A 1 340 ? -29.184 -9.338  34.537  1.00 28.19  ? 319 GLN A C   1 
ATOM   2407  O  O   . GLN A 1 340 ? -29.927 -10.131 33.953  1.00 26.43  ? 319 GLN A O   1 
ATOM   2408  C  CB  . GLN A 1 340 ? -29.547 -8.574  36.901  1.00 22.91  ? 319 GLN A CB  1 
ATOM   2409  C  CG  . GLN A 1 340 ? -29.858 -10.002 37.252  1.00 28.40  ? 319 GLN A CG  1 
ATOM   2410  C  CD  . GLN A 1 340 ? -29.164 -10.398 38.544  1.00 30.00  ? 319 GLN A CD  1 
ATOM   2411  O  OE1 . GLN A 1 340 ? -29.687 -10.130 39.616  1.00 27.22  ? 319 GLN A OE1 1 
ATOM   2412  N  NE2 . GLN A 1 340 ? -27.953 -10.997 38.440  1.00 26.57  ? 319 GLN A NE2 1 
ATOM   2413  N  N   . ARG A 1 341 ? -27.861 -9.427  34.466  1.00 23.26  ? 320 ARG A N   1 
ATOM   2414  C  CA  . ARG A 1 341 ? -27.245 -10.500 33.697  1.00 26.69  ? 320 ARG A CA  1 
ATOM   2415  C  C   . ARG A 1 341 ? -27.010 -11.736 34.551  1.00 24.32  ? 320 ARG A C   1 
ATOM   2416  O  O   . ARG A 1 341 ? -26.761 -11.658 35.753  1.00 24.84  ? 320 ARG A O   1 
ATOM   2417  C  CB  . ARG A 1 341 ? -25.920 -10.045 33.085  1.00 18.37  ? 320 ARG A CB  1 
ATOM   2418  C  CG  . ARG A 1 341 ? -26.089 -9.129  31.862  1.00 25.31  ? 320 ARG A CG  1 
ATOM   2419  C  CD  . ARG A 1 341 ? -24.750 -8.816  31.257  1.00 27.86  ? 320 ARG A CD  1 
ATOM   2420  N  NE  . ARG A 1 341 ? -24.915 -8.001  30.059  1.00 25.74  ? 320 ARG A NE  1 
ATOM   2421  C  CZ  . ARG A 1 341 ? -25.163 -6.699  30.053  1.00 36.09  ? 320 ARG A CZ  1 
ATOM   2422  N  NH1 . ARG A 1 341 ? -25.127 -5.974  31.170  1.00 32.32  ? 320 ARG A NH1 1 
ATOM   2423  N  NH2 . ARG A 1 341 ? -25.459 -6.110  28.902  1.00 35.84  ? 320 ARG A NH2 1 
ATOM   2424  N  N   . VAL A 1 342 ? -27.165 -12.884 33.923  1.00 22.42  ? 321 VAL A N   1 
ATOM   2425  C  CA  . VAL A 1 342 ? -26.686 -14.153 34.431  1.00 22.18  ? 321 VAL A CA  1 
ATOM   2426  C  C   . VAL A 1 342 ? -25.618 -14.594 33.445  1.00 20.37  ? 321 VAL A C   1 
ATOM   2427  O  O   . VAL A 1 342 ? -25.839 -14.553 32.226  1.00 20.63  ? 321 VAL A O   1 
ATOM   2428  C  CB  . VAL A 1 342 ? -27.827 -15.186 34.532  1.00 26.68  ? 321 VAL A CB  1 
ATOM   2429  C  CG1 . VAL A 1 342 ? -27.280 -16.575 34.919  1.00 23.04  ? 321 VAL A CG1 1 
ATOM   2430  C  CG2 . VAL A 1 342 ? -28.883 -14.686 35.501  1.00 27.59  ? 321 VAL A CG2 1 
ATOM   2431  N  N   . ILE A 1 343 ? -24.446 -14.929 33.953  1.00 21.82  ? 322 ILE A N   1 
ATOM   2432  C  CA  . ILE A 1 343 ? -23.302 -15.250 33.106  1.00 19.62  ? 322 ILE A CA  1 
ATOM   2433  C  C   . ILE A 1 343 ? -22.917 -16.691 33.416  1.00 23.50  ? 322 ILE A C   1 
ATOM   2434  O  O   . ILE A 1 343 ? -22.641 -17.033 34.569  1.00 21.39  ? 322 ILE A O   1 
ATOM   2435  C  CB  . ILE A 1 343 ? -22.137 -14.279 33.363  1.00 22.30  ? 322 ILE A CB  1 
ATOM   2436  C  CG1 . ILE A 1 343 ? -22.536 -12.854 32.919  1.00 28.00  ? 322 ILE A CG1 1 
ATOM   2437  C  CG2 . ILE A 1 343 ? -20.855 -14.781 32.684  1.00 19.58  ? 322 ILE A CG2 1 
ATOM   2438  C  CD1 . ILE A 1 343 ? -21.466 -11.823 33.188  1.00 28.39  ? 322 ILE A CD1 1 
ATOM   2439  N  N   . LEU A 1 344 ? -22.985 -17.556 32.412  1.00 21.21  ? 323 LEU A N   1 
ATOM   2440  C  CA  . LEU A 1 344 ? -22.556 -18.942 32.584  1.00 22.09  ? 323 LEU A CA  1 
ATOM   2441  C  C   . LEU A 1 344 ? -21.054 -18.994 32.373  1.00 19.32  ? 323 LEU A C   1 
ATOM   2442  O  O   . LEU A 1 344 ? -20.561 -18.615 31.308  1.00 21.70  ? 323 LEU A O   1 
ATOM   2443  C  CB  . LEU A 1 344 ? -23.275 -19.861 31.581  1.00 22.90  ? 323 LEU A CB  1 
ATOM   2444  C  CG  . LEU A 1 344 ? -22.959 -21.366 31.557  1.00 22.26  ? 323 LEU A CG  1 
ATOM   2445  C  CD1 . LEU A 1 344 ? -23.177 -21.943 32.960  1.00 21.55  ? 323 LEU A CD1 1 
ATOM   2446  C  CD2 . LEU A 1 344 ? -23.830 -22.073 30.509  1.00 18.83  ? 323 LEU A CD2 1 
ATOM   2447  N  N   . ASP A 1 345 ? -20.318 -19.460 33.386  1.00 19.57  ? 324 ASP A N   1 
ATOM   2448  C  CA  . ASP A 1 345 ? -18.867 -19.555 33.297  1.00 24.62  ? 324 ASP A CA  1 
ATOM   2449  C  C   . ASP A 1 345 ? -18.529 -20.879 32.601  1.00 22.57  ? 324 ASP A C   1 
ATOM   2450  O  O   . ASP A 1 345 ? -18.764 -21.946 33.156  1.00 19.52  ? 324 ASP A O   1 
ATOM   2451  C  CB  . ASP A 1 345 ? -18.294 -19.457 34.712  1.00 21.47  ? 324 ASP A CB  1 
ATOM   2452  C  CG  . ASP A 1 345 ? -16.862 -19.901 34.827  1.00 24.77  ? 324 ASP A CG  1 
ATOM   2453  O  OD1 . ASP A 1 345 ? -16.134 -19.949 33.808  1.00 25.57  ? 324 ASP A OD1 1 
ATOM   2454  O  OD2 . ASP A 1 345 ? -16.461 -20.196 35.991  1.00 27.18  ? 324 ASP A OD2 1 
ATOM   2455  N  N   . PHE A 1 346 ? -18.033 -20.808 31.366  1.00 21.14  ? 325 PHE A N   1 
ATOM   2456  C  CA  . PHE A 1 346 ? -17.736 -22.020 30.615  1.00 20.45  ? 325 PHE A CA  1 
ATOM   2457  C  C   . PHE A 1 346 ? -16.478 -22.701 31.139  1.00 18.59  ? 325 PHE A C   1 
ATOM   2458  O  O   . PHE A 1 346 ? -16.466 -23.915 31.358  1.00 23.43  ? 325 PHE A O   1 
ATOM   2459  C  CB  . PHE A 1 346 ? -17.566 -21.681 29.127  1.00 20.41  ? 325 PHE A CB  1 
ATOM   2460  C  CG  . PHE A 1 346 ? -18.860 -21.533 28.361  1.00 19.52  ? 325 PHE A CG  1 
ATOM   2461  C  CD1 . PHE A 1 346 ? -19.901 -20.803 28.878  1.00 20.28  ? 325 PHE A CD1 1 
ATOM   2462  C  CD2 . PHE A 1 346 ? -19.002 -22.118 27.095  1.00 23.64  ? 325 PHE A CD2 1 
ATOM   2463  C  CE1 . PHE A 1 346 ? -21.104 -20.668 28.188  1.00 22.20  ? 325 PHE A CE1 1 
ATOM   2464  C  CE2 . PHE A 1 346 ? -20.188 -21.968 26.369  1.00 25.34  ? 325 PHE A CE2 1 
ATOM   2465  C  CZ  . PHE A 1 346 ? -21.239 -21.238 26.917  1.00 26.06  ? 325 PHE A CZ  1 
ATOM   2466  N  N   . VAL A 1 347 ? -15.389 -21.945 31.307  1.00 20.40  ? 326 VAL A N   1 
ATOM   2467  C  CA  . VAL A 1 347 ? -14.145 -22.546 31.798  1.00 22.17  ? 326 VAL A CA  1 
ATOM   2468  C  C   . VAL A 1 347 ? -14.375 -23.236 33.133  1.00 21.32  ? 326 VAL A C   1 
ATOM   2469  O  O   . VAL A 1 347 ? -13.922 -24.371 33.363  1.00 22.53  ? 326 VAL A O   1 
ATOM   2470  C  CB  . VAL A 1 347 ? -13.065 -21.467 31.911  1.00 27.42  ? 326 VAL A CB  1 
ATOM   2471  C  CG1 . VAL A 1 347 ? -11.810 -22.036 32.680  1.00 25.88  ? 326 VAL A CG1 1 
ATOM   2472  C  CG2 . VAL A 1 347 ? -12.715 -20.996 30.528  1.00 24.69  ? 326 VAL A CG2 1 
ATOM   2473  N  N   . GLY A 1 348 ? -15.127 -22.580 34.017  1.00 19.90  ? 327 GLY A N   1 
ATOM   2474  C  CA  . GLY A 1 348 ? -15.400 -23.132 35.330  1.00 19.05  ? 327 GLY A CA  1 
ATOM   2475  C  C   . GLY A 1 348 ? -16.339 -24.314 35.303  1.00 24.17  ? 327 GLY A C   1 
ATOM   2476  O  O   . GLY A 1 348 ? -16.380 -25.070 36.272  1.00 23.49  ? 327 GLY A O   1 
ATOM   2477  N  N   . THR A 1 349 ? -17.094 -24.503 34.220  1.00 19.81  ? 328 THR A N   1 
ATOM   2478  C  CA  . THR A 1 349 ? -17.905 -25.718 34.113  1.00 20.25  ? 328 THR A CA  1 
ATOM   2479  C  C   . THR A 1 349 ? -17.113 -26.864 33.505  1.00 23.28  ? 328 THR A C   1 
ATOM   2480  O  O   . THR A 1 349 ? -17.226 -28.023 33.955  1.00 22.68  ? 328 THR A O   1 
ATOM   2481  C  CB  . THR A 1 349 ? -19.156 -25.444 33.259  1.00 22.24  ? 328 THR A CB  1 
ATOM   2482  O  OG1 . THR A 1 349 ? -19.970 -24.445 33.909  1.00 23.60  ? 328 THR A OG1 1 
ATOM   2483  C  CG2 . THR A 1 349 ? -20.000 -26.727 33.135  1.00 16.62  ? 328 THR A CG2 1 
ATOM   2484  N  N   . LEU A 1 350 ? -16.346 -26.551 32.461  1.00 18.03  ? 329 LEU A N   1 
ATOM   2485  C  CA  . LEU A 1 350 ? -15.496 -27.526 31.804  1.00 18.65  ? 329 LEU A CA  1 
ATOM   2486  C  C   . LEU A 1 350 ? -14.385 -28.008 32.728  1.00 22.83  ? 329 LEU A C   1 
ATOM   2487  O  O   . LEU A 1 350 ? -13.875 -29.126 32.534  1.00 19.42  ? 329 LEU A O   1 
ATOM   2488  C  CB  . LEU A 1 350 ? -14.897 -26.903 30.528  1.00 19.00  ? 329 LEU A CB  1 
ATOM   2489  C  CG  . LEU A 1 350 ? -15.903 -26.571 29.417  1.00 22.55  ? 329 LEU A CG  1 
ATOM   2490  C  CD1 . LEU A 1 350 ? -15.259 -25.676 28.391  1.00 24.07  ? 329 LEU A CD1 1 
ATOM   2491  C  CD2 . LEU A 1 350 ? -16.483 -27.866 28.763  1.00 18.12  ? 329 LEU A CD2 1 
ATOM   2492  N  N   . HIS A 1 351 ? -14.043 -27.224 33.760  1.00 18.34  ? 330 HIS A N   1 
ATOM   2493  C  CA  . HIS A 1 351 ? -12.930 -27.587 34.646  1.00 20.99  ? 330 HIS A CA  1 
ATOM   2494  C  C   . HIS A 1 351 ? -13.376 -27.815 36.072  1.00 24.12  ? 330 HIS A C   1 
ATOM   2495  O  O   . HIS A 1 351 ? -12.539 -27.866 36.984  1.00 21.01  ? 330 HIS A O   1 
ATOM   2496  C  CB  . HIS A 1 351 ? -11.825 -26.535 34.607  1.00 21.45  ? 330 HIS A CB  1 
ATOM   2497  C  CG  . HIS A 1 351 ? -10.998 -26.619 33.368  1.00 25.42  ? 330 HIS A CG  1 
ATOM   2498  N  ND1 . HIS A 1 351 ? -9.813  -27.330 33.308  1.00 28.25  ? 330 HIS A ND1 1 
ATOM   2499  C  CD2 . HIS A 1 351 ? -11.208 -26.118 32.127  1.00 24.53  ? 330 HIS A CD2 1 
ATOM   2500  C  CE1 . HIS A 1 351 ? -9.311  -27.223 32.088  1.00 24.65  ? 330 HIS A CE1 1 
ATOM   2501  N  NE2 . HIS A 1 351 ? -10.143 -26.503 31.351  1.00 25.40  ? 330 HIS A NE2 1 
ATOM   2502  N  N   . SER A 1 352 ? -14.676 -27.958 36.280  1.00 20.28  ? 331 SER A N   1 
ATOM   2503  C  CA  . SER A 1 352 ? -15.197 -28.099 37.627  1.00 18.77  ? 331 SER A CA  1 
ATOM   2504  C  C   . SER A 1 352 ? -14.840 -29.473 38.192  1.00 23.73  ? 331 SER A C   1 
ATOM   2505  O  O   . SER A 1 352 ? -15.138 -30.499 37.580  1.00 23.59  ? 331 SER A O   1 
ATOM   2506  C  CB  . SER A 1 352 ? -16.715 -27.916 37.611  1.00 24.71  ? 331 SER A CB  1 
ATOM   2507  O  OG  . SER A 1 352 ? -17.263 -28.477 38.781  1.00 27.36  ? 331 SER A OG  1 
ATOM   2508  N  N   . ALA A 1 353 ? -14.242 -29.492 39.391  1.00 22.64  ? 332 ALA A N   1 
ATOM   2509  C  CA  . ALA A 1 353 ? -13.950 -30.770 40.029  1.00 24.94  ? 332 ALA A CA  1 
ATOM   2510  C  C   . ALA A 1 353 ? -15.218 -31.454 40.532  1.00 27.73  ? 332 ALA A C   1 
ATOM   2511  O  O   . ALA A 1 353 ? -15.197 -32.660 40.774  1.00 25.17  ? 332 ALA A O   1 
ATOM   2512  C  CB  . ALA A 1 353 ? -12.964 -30.581 41.175  1.00 26.06  ? 332 ALA A CB  1 
ATOM   2513  N  N   . GLU A 1 354 ? -16.329 -30.733 40.657  1.00 25.22  ? 333 GLU A N   1 
ATOM   2514  C  CA  . GLU A 1 354 ? -17.582 -31.425 40.973  1.00 30.38  ? 333 GLU A CA  1 
ATOM   2515  C  C   . GLU A 1 354 ? -18.178 -32.146 39.775  1.00 29.47  ? 333 GLU A C   1 
ATOM   2516  O  O   . GLU A 1 354 ? -18.954 -33.081 39.968  1.00 33.85  ? 333 GLU A O   1 
ATOM   2517  C  CB  . GLU A 1 354 ? -18.634 -30.453 41.522  1.00 27.77  ? 333 GLU A CB  1 
ATOM   2518  C  CG  . GLU A 1 354 ? -18.211 -29.793 42.805  1.00 40.05  ? 333 GLU A CG  1 
ATOM   2519  C  CD  . GLU A 1 354 ? -18.169 -30.792 43.940  1.00 62.89  ? 333 GLU A CD  1 
ATOM   2520  O  OE1 . GLU A 1 354 ? -19.056 -31.680 43.976  1.00 65.42  ? 333 GLU A OE1 1 
ATOM   2521  O  OE2 . GLU A 1 354 ? -17.247 -30.702 44.780  1.00 81.20  ? 333 GLU A OE2 1 
ATOM   2522  N  N   . GLU A 1 355 ? -17.855 -31.724 38.551  1.00 25.59  ? 334 GLU A N   1 
ATOM   2523  C  CA  . GLU A 1 355 ? -18.456 -32.269 37.337  1.00 25.40  ? 334 GLU A CA  1 
ATOM   2524  C  C   . GLU A 1 355 ? -17.563 -33.282 36.623  1.00 25.18  ? 334 GLU A C   1 
ATOM   2525  O  O   . GLU A 1 355 ? -18.073 -34.058 35.810  1.00 27.31  ? 334 GLU A O   1 
ATOM   2526  C  CB  . GLU A 1 355 ? -18.769 -31.136 36.325  1.00 26.04  ? 334 GLU A CB  1 
ATOM   2527  C  CG  . GLU A 1 355 ? -19.641 -29.966 36.823  1.00 32.66  ? 334 GLU A CG  1 
ATOM   2528  C  CD  . GLU A 1 355 ? -21.112 -30.334 36.931  1.00 38.96  ? 334 GLU A CD  1 
ATOM   2529  O  OE1 . GLU A 1 355 ? -21.512 -31.387 36.391  1.00 40.77  ? 334 GLU A OE1 1 
ATOM   2530  O  OE2 . GLU A 1 355 ? -21.872 -29.581 37.576  1.00 32.76  ? 334 GLU A OE2 1 
ATOM   2531  N  N   . TRP A 1 356 ? -16.251 -33.257 36.868  1.00 21.75  ? 335 TRP A N   1 
ATOM   2532  C  CA  . TRP A 1 356 ? -15.281 -34.071 36.141  1.00 26.09  ? 335 TRP A CA  1 
ATOM   2533  C  C   . TRP A 1 356 ? -14.300 -34.689 37.134  1.00 24.67  ? 335 TRP A C   1 
ATOM   2534  O  O   . TRP A 1 356 ? -13.913 -34.051 38.124  1.00 26.38  ? 335 TRP A O   1 
ATOM   2535  C  CB  . TRP A 1 356 ? -14.454 -33.234 35.146  1.00 23.78  ? 335 TRP A CB  1 
ATOM   2536  C  CG  . TRP A 1 356 ? -15.270 -32.436 34.156  1.00 22.07  ? 335 TRP A CG  1 
ATOM   2537  C  CD1 . TRP A 1 356 ? -15.771 -31.183 34.337  1.00 24.30  ? 335 TRP A CD1 1 
ATOM   2538  C  CD2 . TRP A 1 356 ? -15.696 -32.864 32.861  1.00 23.34  ? 335 TRP A CD2 1 
ATOM   2539  N  NE1 . TRP A 1 356 ? -16.464 -30.788 33.221  1.00 20.15  ? 335 TRP A NE1 1 
ATOM   2540  C  CE2 . TRP A 1 356 ? -16.439 -31.806 32.298  1.00 23.60  ? 335 TRP A CE2 1 
ATOM   2541  C  CE3 . TRP A 1 356 ? -15.496 -34.042 32.107  1.00 19.73  ? 335 TRP A CE3 1 
ATOM   2542  C  CZ2 . TRP A 1 356 ? -17.007 -31.890 31.032  1.00 19.95  ? 335 TRP A CZ2 1 
ATOM   2543  C  CZ3 . TRP A 1 356 ? -16.040 -34.134 30.867  1.00 19.27  ? 335 TRP A CZ3 1 
ATOM   2544  C  CH2 . TRP A 1 356 ? -16.803 -33.051 30.321  1.00 19.02  ? 335 TRP A CH2 1 
ATOM   2545  N  N   . ASP A 1 357 ? -13.811 -35.871 36.804  1.00 23.04  ? 336 ASP A N   1 
ATOM   2546  C  CA  . ASP A 1 357 ? -12.711 -36.463 37.554  1.00 25.30  ? 336 ASP A CA  1 
ATOM   2547  C  C   . ASP A 1 357 ? -11.401 -35.878 37.057  1.00 26.61  ? 336 ASP A C   1 
ATOM   2548  O  O   . ASP A 1 357 ? -11.141 -35.877 35.846  1.00 28.21  ? 336 ASP A O   1 
ATOM   2549  C  CB  . ASP A 1 357 ? -12.697 -37.983 37.376  1.00 30.88  ? 336 ASP A CB  1 
ATOM   2550  C  CG  . ASP A 1 357 ? -13.866 -38.678 38.094  1.00 65.35  ? 336 ASP A CG  1 
ATOM   2551  O  OD1 . ASP A 1 357 ? -14.442 -38.084 39.039  1.00 62.37  ? 336 ASP A OD1 1 
ATOM   2552  O  OD2 . ASP A 1 357 ? -14.208 -39.823 37.712  1.00 62.85  ? 336 ASP A OD2 1 
ATOM   2553  N  N   . ASN A 1 358 ? -10.578 -35.393 37.985  1.00 25.90  ? 337 ASN A N   1 
ATOM   2554  C  CA  . ASN A 1 358 ? -9.297  -34.778 37.645  1.00 25.99  ? 337 ASN A CA  1 
ATOM   2555  C  C   . ASN A 1 358 ? -9.386  -33.796 36.478  1.00 26.86  ? 337 ASN A C   1 
ATOM   2556  O  O   . ASN A 1 358 ? -8.780  -34.040 35.421  1.00 23.40  ? 337 ASN A O   1 
ATOM   2557  C  CB  . ASN A 1 358 ? -8.270  -35.860 37.312  1.00 26.98  ? 337 ASN A CB  1 
ATOM   2558  C  CG  . ASN A 1 358 ? -8.049  -36.821 38.475  1.00 28.87  ? 337 ASN A CG  1 
ATOM   2559  O  OD1 . ASN A 1 358 ? -7.595  -36.412 39.538  1.00 33.11  ? 337 ASN A OD1 1 
ATOM   2560  N  ND2 . ASN A 1 358 ? -8.380  -38.094 38.271  1.00 29.06  ? 337 ASN A ND2 1 
ATOM   2561  N  N   . PRO A 1 359 ? -10.119 -32.690 36.630  1.00 26.31  ? 338 PRO A N   1 
ATOM   2562  C  CA  . PRO A 1 359 ? -10.334 -31.778 35.486  1.00 22.93  ? 338 PRO A CA  1 
ATOM   2563  C  C   . PRO A 1 359 ? -9.076  -31.097 34.991  1.00 19.58  ? 338 PRO A C   1 
ATOM   2564  O  O   . PRO A 1 359 ? -9.076  -30.628 33.838  1.00 21.47  ? 338 PRO A O   1 
ATOM   2565  C  CB  . PRO A 1 359 ? -11.331 -30.740 36.040  1.00 28.27  ? 338 PRO A CB  1 
ATOM   2566  C  CG  . PRO A 1 359 ? -11.137 -30.798 37.566  1.00 22.58  ? 338 PRO A CG  1 
ATOM   2567  C  CD  . PRO A 1 359 ? -10.890 -32.285 37.813  1.00 26.45  ? 338 PRO A CD  1 
ATOM   2568  N  N   . ALA A 1 360 ? -8.012  -30.972 35.814  1.00 21.36  ? 339 ALA A N   1 
ATOM   2569  C  CA  . ALA A 1 360 ? -6.819  -30.325 35.266  1.00 24.51  ? 339 ALA A CA  1 
ATOM   2570  C  C   . ALA A 1 360 ? -6.000  -31.253 34.387  1.00 21.52  ? 339 ALA A C   1 
ATOM   2571  O  O   . ALA A 1 360 ? -5.013  -30.802 33.777  1.00 22.18  ? 339 ALA A O   1 
ATOM   2572  C  CB  . ALA A 1 360 ? -5.897  -29.767 36.354  1.00 22.36  ? 339 ALA A CB  1 
ATOM   2573  N  N   . SER A 1 361 ? -6.370  -32.521 34.329  1.00 21.59  ? 340 SER A N   1 
ATOM   2574  C  CA  . SER A 1 361 ? -5.669  -33.517 33.525  1.00 22.69  ? 340 SER A CA  1 
ATOM   2575  C  C   . SER A 1 361 ? -6.220  -33.556 32.105  1.00 22.12  ? 340 SER A C   1 
ATOM   2576  O  O   . SER A 1 361 ? -7.426  -33.751 31.913  1.00 19.57  ? 340 SER A O   1 
ATOM   2577  C  CB  . SER A 1 361 ? -5.818  -34.888 34.184  1.00 27.74  ? 340 SER A CB  1 
ATOM   2578  O  OG  . SER A 1 361 ? -5.202  -35.899 33.402  1.00 26.16  ? 340 SER A OG  1 
ATOM   2579  N  N   . PHE A 1 362 ? -5.334  -33.397 31.112  1.00 19.96  ? 341 PHE A N   1 
ATOM   2580  C  CA  . PHE A 1 362 ? -5.721  -33.605 29.728  1.00 23.41  ? 341 PHE A CA  1 
ATOM   2581  C  C   . PHE A 1 362 ? -5.738  -35.103 29.473  1.00 21.47  ? 341 PHE A C   1 
ATOM   2582  O  O   . PHE A 1 362 ? -4.687  -35.752 29.505  1.00 20.27  ? 341 PHE A O   1 
ATOM   2583  C  CB  . PHE A 1 362 ? -4.771  -32.896 28.769  1.00 24.79  ? 341 PHE A CB  1 
ATOM   2584  C  CG  . PHE A 1 362 ? -5.106  -33.133 27.324  1.00 20.06  ? 341 PHE A CG  1 
ATOM   2585  C  CD1 . PHE A 1 362 ? -4.562  -34.215 26.643  1.00 20.18  ? 341 PHE A CD1 1 
ATOM   2586  C  CD2 . PHE A 1 362 ? -5.972  -32.279 26.646  1.00 20.85  ? 341 PHE A CD2 1 
ATOM   2587  C  CE1 . PHE A 1 362 ? -4.858  -34.434 25.298  1.00 23.62  ? 341 PHE A CE1 1 
ATOM   2588  C  CE2 . PHE A 1 362 ? -6.263  -32.492 25.269  1.00 19.22  ? 341 PHE A CE2 1 
ATOM   2589  C  CZ  . PHE A 1 362 ? -5.718  -33.574 24.617  1.00 19.50  ? 341 PHE A CZ  1 
ATOM   2590  N  N   . ASP A 1 363 ? -6.922  -35.666 29.245  1.00 18.52  ? 342 ASP A N   1 
ATOM   2591  C  CA  . ASP A 1 363 ? -7.080  -37.122 29.228  1.00 21.44  ? 342 ASP A CA  1 
ATOM   2592  C  C   . ASP A 1 363 ? -8.165  -37.513 28.246  1.00 20.84  ? 342 ASP A C   1 
ATOM   2593  O  O   . ASP A 1 363 ? -9.343  -37.577 28.606  1.00 22.74  ? 342 ASP A O   1 
ATOM   2594  C  CB  . ASP A 1 363 ? -7.430  -37.659 30.610  1.00 24.10  ? 342 ASP A CB  1 
ATOM   2595  C  CG  . ASP A 1 363 ? -7.325  -39.177 30.674  1.00 41.75  ? 342 ASP A CG  1 
ATOM   2596  O  OD1 . ASP A 1 363 ? -6.988  -39.805 29.634  1.00 28.72  ? 342 ASP A OD1 1 
ATOM   2597  O  OD2 . ASP A 1 363 ? -7.575  -39.728 31.768  1.00 37.82  ? 342 ASP A OD2 1 
ATOM   2598  N  N   . PRO A 1 364 ? -7.798  -37.840 27.001  1.00 20.81  ? 343 PRO A N   1 
ATOM   2599  C  CA  . PRO A 1 364 ? -8.819  -38.251 26.014  1.00 20.93  ? 343 PRO A CA  1 
ATOM   2600  C  C   . PRO A 1 364 ? -9.536  -39.533 26.381  1.00 21.19  ? 343 PRO A C   1 
ATOM   2601  O  O   . PRO A 1 364 ? -10.616 -39.810 25.805  1.00 21.44  ? 343 PRO A O   1 
ATOM   2602  C  CB  . PRO A 1 364 ? -8.017  -38.396 24.709  1.00 23.56  ? 343 PRO A CB  1 
ATOM   2603  C  CG  . PRO A 1 364 ? -6.826  -37.425 24.923  1.00 18.17  ? 343 PRO A CG  1 
ATOM   2604  C  CD  . PRO A 1 364 ? -6.486  -37.587 26.385  1.00 22.11  ? 343 PRO A CD  1 
ATOM   2605  N  N   . GLU A 1 365 ? -9.038  -40.302 27.368  1.00 22.80  ? 344 GLU A N   1 
ATOM   2606  C  CA  . GLU A 1 365 ? -9.813  -41.474 27.794  1.00 22.07  ? 344 GLU A CA  1 
ATOM   2607  C  C   . GLU A 1 365 ? -11.222 -41.099 28.233  1.00 26.48  ? 344 GLU A C   1 
ATOM   2608  O  O   . GLU A 1 365 ? -12.139 -41.920 28.103  1.00 23.66  ? 344 GLU A O   1 
ATOM   2609  C  CB  . GLU A 1 365 ? -9.111  -42.225 28.934  1.00 29.27  ? 344 GLU A CB  1 
ATOM   2610  C  CG  . GLU A 1 365 ? -7.783  -42.867 28.570  1.00 35.78  ? 344 GLU A CG  1 
ATOM   2611  C  CD  . GLU A 1 365 ? -7.873  -44.116 27.664  1.00 46.33  ? 344 GLU A CD  1 
ATOM   2612  O  OE1 . GLU A 1 365 ? -8.996  -44.587 27.329  1.00 35.85  ? 344 GLU A OE1 1 
ATOM   2613  O  OE2 . GLU A 1 365 ? -6.779  -44.627 27.292  1.00 39.57  ? 344 GLU A OE2 1 
ATOM   2614  N  N   . ARG A 1 366 ? -11.428 -39.868 28.731  1.00 25.67  ? 345 ARG A N   1 
ATOM   2615  C  CA  . ARG A 1 366 ? -12.776 -39.414 29.104  1.00 24.53  ? 345 ARG A CA  1 
ATOM   2616  C  C   . ARG A 1 366 ? -13.794 -39.643 28.015  1.00 26.26  ? 345 ARG A C   1 
ATOM   2617  O  O   . ARG A 1 366 ? -14.984 -39.779 28.295  1.00 26.48  ? 345 ARG A O   1 
ATOM   2618  C  CB  . ARG A 1 366 ? -12.830 -37.896 29.340  1.00 28.29  ? 345 ARG A CB  1 
ATOM   2619  C  CG  . ARG A 1 366 ? -12.138 -37.403 30.472  1.00 35.81  ? 345 ARG A CG  1 
ATOM   2620  C  CD  . ARG A 1 366 ? -12.214 -35.880 30.418  1.00 19.03  ? 345 ARG A CD  1 
ATOM   2621  N  NE  . ARG A 1 366 ? -11.033 -35.435 31.122  1.00 23.13  ? 345 ARG A NE  1 
ATOM   2622  C  CZ  . ARG A 1 366 ? -10.903 -35.449 32.438  1.00 28.15  ? 345 ARG A CZ  1 
ATOM   2623  N  NH1 . ARG A 1 366 ? -11.877 -35.904 33.225  1.00 25.49  ? 345 ARG A NH1 1 
ATOM   2624  N  NH2 . ARG A 1 366 ? -9.769  -35.003 32.977  1.00 24.75  ? 345 ARG A NH2 1 
ATOM   2625  N  N   . PHE A 1 367 ? -13.376 -39.553 26.764  1.00 19.52  ? 346 PHE A N   1 
ATOM   2626  C  CA  . PHE A 1 367 ? -14.303 -39.584 25.657  1.00 20.52  ? 346 PHE A CA  1 
ATOM   2627  C  C   . PHE A 1 367 ? -14.179 -40.848 24.821  1.00 18.66  ? 346 PHE A C   1 
ATOM   2628  O  O   . PHE A 1 367 ? -14.845 -40.946 23.816  1.00 21.83  ? 346 PHE A O   1 
ATOM   2629  C  CB  . PHE A 1 367 ? -14.100 -38.346 24.782  1.00 24.46  ? 346 PHE A CB  1 
ATOM   2630  C  CG  . PHE A 1 367 ? -14.512 -37.086 25.453  1.00 23.54  ? 346 PHE A CG  1 
ATOM   2631  C  CD1 . PHE A 1 367 ? -15.855 -36.762 25.580  1.00 27.06  ? 346 PHE A CD1 1 
ATOM   2632  C  CD2 . PHE A 1 367 ? -13.566 -36.220 25.949  1.00 18.63  ? 346 PHE A CD2 1 
ATOM   2633  C  CE1 . PHE A 1 367 ? -16.238 -35.590 26.244  1.00 26.37  ? 346 PHE A CE1 1 
ATOM   2634  C  CE2 . PHE A 1 367 ? -13.959 -35.023 26.600  1.00 24.11  ? 346 PHE A CE2 1 
ATOM   2635  C  CZ  . PHE A 1 367 ? -15.280 -34.725 26.734  1.00 24.07  ? 346 PHE A CZ  1 
ATOM   2636  N  N   . MET A 1 368 ? -13.307 -41.791 25.201  1.00 21.91  ? 347 MET A N   1 
ATOM   2637  C  CA  . MET A 1 368 ? -13.071 -42.964 24.359  1.00 25.59  ? 347 MET A CA  1 
ATOM   2638  C  C   . MET A 1 368 ? -14.279 -43.890 24.269  1.00 26.36  ? 347 MET A C   1 
ATOM   2639  O  O   . MET A 1 368 ? -14.378 -44.645 23.307  1.00 24.28  ? 347 MET A O   1 
ATOM   2640  C  CB  . MET A 1 368 ? -11.854 -43.759 24.864  1.00 23.41  ? 347 MET A CB  1 
ATOM   2641  C  CG  . MET A 1 368 ? -10.516 -43.144 24.368  1.00 24.91  ? 347 MET A CG  1 
ATOM   2642  S  SD  . MET A 1 368 ? -10.314 -43.316 22.577  1.00 25.14  ? 347 MET A SD  1 
ATOM   2643  C  CE  . MET A 1 368 ? -10.235 -45.122 22.420  1.00 25.03  ? 347 MET A CE  1 
ATOM   2644  N  N   . ALA A 1 369 ? -15.206 -43.833 25.211  1.00 22.43  ? 348 ALA A N   1 
ATOM   2645  C  CA  . ALA A 1 369 ? -16.396 -44.675 25.100  1.00 22.41  ? 348 ALA A CA  1 
ATOM   2646  C  C   . ALA A 1 369 ? -17.478 -44.083 24.204  1.00 27.47  ? 348 ALA A C   1 
ATOM   2647  O  O   . ALA A 1 369 ? -18.454 -44.783 23.908  1.00 25.12  ? 348 ALA A O   1 
ATOM   2648  C  CB  . ALA A 1 369 ? -16.969 -44.946 26.491  1.00 26.26  ? 348 ALA A CB  1 
ATOM   2649  N  N   . TYR A 1 370 ? -17.308 -42.843 23.739  1.00 23.57  ? 349 TYR A N   1 
ATOM   2650  C  CA  . TYR A 1 370 ? -18.285 -42.130 22.926  1.00 28.31  ? 349 TYR A CA  1 
ATOM   2651  C  C   . TYR A 1 370 ? -17.904 -42.224 21.459  1.00 27.34  ? 349 TYR A C   1 
ATOM   2652  O  O   . TYR A 1 370 ? -16.717 -42.195 21.104  1.00 27.75  ? 349 TYR A O   1 
ATOM   2653  C  CB  . TYR A 1 370 ? -18.369 -40.644 23.331  1.00 21.70  ? 349 TYR A CB  1 
ATOM   2654  C  CG  . TYR A 1 370 ? -18.941 -40.450 24.702  1.00 21.02  ? 349 TYR A CG  1 
ATOM   2655  C  CD1 . TYR A 1 370 ? -18.164 -40.691 25.848  1.00 22.06  ? 349 TYR A CD1 1 
ATOM   2656  C  CD2 . TYR A 1 370 ? -20.282 -40.076 24.861  1.00 22.08  ? 349 TYR A CD2 1 
ATOM   2657  C  CE1 . TYR A 1 370 ? -18.702 -40.571 27.102  1.00 19.39  ? 349 TYR A CE1 1 
ATOM   2658  C  CE2 . TYR A 1 370 ? -20.820 -39.934 26.118  1.00 22.26  ? 349 TYR A CE2 1 
ATOM   2659  C  CZ  . TYR A 1 370 ? -20.029 -40.180 27.230  1.00 21.99  ? 349 TYR A CZ  1 
ATOM   2660  O  OH  . TYR A 1 370 ? -20.566 -40.051 28.483  1.00 23.44  ? 349 TYR A OH  1 
ATOM   2661  N  N   . GLU A 1 371 ? -18.915 -42.317 20.597  1.00 22.27  ? 350 GLU A N   1 
ATOM   2662  C  CA  . GLU A 1 371 ? -18.655 -42.540 19.182  1.00 25.55  ? 350 GLU A CA  1 
ATOM   2663  C  C   . GLU A 1 371 ? -19.056 -41.383 18.282  1.00 26.04  ? 350 GLU A C   1 
ATOM   2664  O  O   . GLU A 1 371 ? -18.519 -41.276 17.184  1.00 29.48  ? 350 GLU A O   1 
ATOM   2665  C  CB  . GLU A 1 371 ? -19.388 -43.802 18.706  1.00 29.08  ? 350 GLU A CB  1 
ATOM   2666  C  CG  . GLU A 1 371 ? -18.854 -45.071 19.385  1.00 40.96  ? 350 GLU A CG  1 
ATOM   2667  C  CD  . GLU A 1 371 ? -19.662 -46.323 19.040  1.00 48.42  ? 350 GLU A CD  1 
ATOM   2668  O  OE1 . GLU A 1 371 ? -20.677 -46.204 18.316  1.00 52.72  ? 350 GLU A OE1 1 
ATOM   2669  O  OE2 . GLU A 1 371 ? -19.288 -47.418 19.518  1.00 60.35  ? 350 GLU A OE2 1 
ATOM   2670  N  N   . THR A 1 372 ? -19.987 -40.531 18.700  1.00 22.85  ? 351 THR A N   1 
ATOM   2671  C  CA  . THR A 1 372 ? -20.442 -39.430 17.858  1.00 24.31  ? 351 THR A CA  1 
ATOM   2672  C  C   . THR A 1 372 ? -20.595 -38.172 18.692  1.00 20.07  ? 351 THR A C   1 
ATOM   2673  O  O   . THR A 1 372 ? -20.712 -38.230 19.917  1.00 21.58  ? 351 THR A O   1 
ATOM   2674  C  CB  . THR A 1 372 ? -21.802 -39.729 17.212  1.00 24.93  ? 351 THR A CB  1 
ATOM   2675  O  OG1 . THR A 1 372 ? -22.789 -39.864 18.241  1.00 25.01  ? 351 THR A OG1 1 
ATOM   2676  C  CG2 . THR A 1 372 ? -21.759 -40.988 16.408  1.00 30.83  ? 351 THR A CG2 1 
ATOM   2677  N  N   . GLN A 1 373 ? -20.639 -37.027 18.004  1.00 21.01  ? 352 GLN A N   1 
ATOM   2678  C  CA  . GLN A 1 373 ? -20.934 -35.783 18.708  1.00 23.26  ? 352 GLN A CA  1 
ATOM   2679  C  C   . GLN A 1 373 ? -22.329 -35.822 19.314  1.00 22.65  ? 352 GLN A C   1 
ATOM   2680  O  O   . GLN A 1 373 ? -22.549 -35.315 20.412  1.00 21.61  ? 352 GLN A O   1 
ATOM   2681  C  CB  . GLN A 1 373 ? -20.765 -34.576 17.758  1.00 23.97  ? 352 GLN A CB  1 
ATOM   2682  C  CG  . GLN A 1 373 ? -21.311 -33.238 18.318  1.00 23.12  ? 352 GLN A CG  1 
ATOM   2683  C  CD  . GLN A 1 373 ? -20.764 -32.897 19.688  1.00 25.46  ? 352 GLN A CD  1 
ATOM   2684  O  OE1 . GLN A 1 373 ? -19.672 -33.316 20.050  1.00 24.21  ? 352 GLN A OE1 1 
ATOM   2685  N  NE2 . GLN A 1 373 ? -21.504 -32.097 20.443  1.00 23.52  ? 352 GLN A NE2 1 
ATOM   2686  N  N   . SER A 1 374 ? -23.281 -36.454 18.627  1.00 22.48  ? 353 SER A N   1 
ATOM   2687  C  CA  . SER A 1 374 ? -24.630 -36.561 19.182  1.00 23.48  ? 353 SER A CA  1 
ATOM   2688  C  C   . SER A 1 374 ? -24.608 -37.280 20.533  1.00 23.37  ? 353 SER A C   1 
ATOM   2689  O  O   . SER A 1 374 ? -25.282 -36.867 21.485  1.00 26.81  ? 353 SER A O   1 
ATOM   2690  C  CB  . SER A 1 374 ? -25.542 -37.302 18.188  1.00 28.60  ? 353 SER A CB  1 
ATOM   2691  O  OG  . SER A 1 374 ? -26.798 -37.545 18.764  1.00 39.88  ? 353 SER A OG  1 
ATOM   2692  N  N   . GLU A 1 375 ? -23.823 -38.351 20.638  1.00 23.52  ? 354 GLU A N   1 
ATOM   2693  C  CA  . GLU A 1 375 ? -23.684 -39.024 21.920  1.00 23.46  ? 354 GLU A CA  1 
ATOM   2694  C  C   . GLU A 1 375 ? -22.969 -38.143 22.941  1.00 25.74  ? 354 GLU A C   1 
ATOM   2695  O  O   . GLU A 1 375 ? -23.344 -38.130 24.114  1.00 22.74  ? 354 GLU A O   1 
ATOM   2696  C  CB  . GLU A 1 375 ? -22.952 -40.362 21.728  1.00 25.29  ? 354 GLU A CB  1 
ATOM   2697  C  CG  . GLU A 1 375 ? -22.982 -41.275 22.941  1.00 27.26  ? 354 GLU A CG  1 
ATOM   2698  C  CD  . GLU A 1 375 ? -22.318 -42.632 22.696  1.00 28.95  ? 354 GLU A CD  1 
ATOM   2699  O  OE1 . GLU A 1 375 ? -21.536 -42.771 21.732  1.00 29.09  ? 354 GLU A OE1 1 
ATOM   2700  O  OE2 . GLU A 1 375 ? -22.573 -43.564 23.484  1.00 32.65  ? 354 GLU A OE2 1 
ATOM   2701  N  N   . ALA A 1 376 ? -21.944 -37.384 22.517  1.00 24.96  ? 355 ALA A N   1 
ATOM   2702  C  CA  . ALA A 1 376 ? -21.267 -36.502 23.471  1.00 22.84  ? 355 ALA A CA  1 
ATOM   2703  C  C   . ALA A 1 376 ? -22.190 -35.416 24.031  1.00 23.02  ? 355 ALA A C   1 
ATOM   2704  O  O   . ALA A 1 376 ? -21.930 -34.923 25.134  1.00 23.62  ? 355 ALA A O   1 
ATOM   2705  C  CB  . ALA A 1 376 ? -20.031 -35.876 22.815  1.00 23.47  ? 355 ALA A CB  1 
ATOM   2706  N  N   . GLU A 1 377 ? -23.263 -35.057 23.311  1.00 23.88  ? 356 GLU A N   1 
ATOM   2707  C  CA  . GLU A 1 377 ? -24.247 -34.095 23.816  1.00 26.46  ? 356 GLU A CA  1 
ATOM   2708  C  C   . GLU A 1 377 ? -24.887 -34.539 25.121  1.00 33.53  ? 356 GLU A C   1 
ATOM   2709  O  O   . GLU A 1 377 ? -25.359 -33.696 25.883  1.00 29.34  ? 356 GLU A O   1 
ATOM   2710  C  CB  . GLU A 1 377 ? -25.393 -33.866 22.823  1.00 29.23  ? 356 GLU A CB  1 
ATOM   2711  C  CG  . GLU A 1 377 ? -25.037 -33.093 21.640  1.00 25.52  ? 356 GLU A CG  1 
ATOM   2712  C  CD  . GLU A 1 377 ? -26.255 -32.833 20.728  1.00 40.70  ? 356 GLU A CD  1 
ATOM   2713  O  OE1 . GLU A 1 377 ? -27.330 -33.451 20.927  1.00 49.80  ? 356 GLU A OE1 1 
ATOM   2714  O  OE2 . GLU A 1 377 ? -26.122 -32.026 19.800  1.00 33.97  ? 356 GLU A OE2 1 
ATOM   2715  N  N   . THR A 1 378 ? -24.938 -35.847 25.388  1.00 24.32  ? 357 THR A N   1 
ATOM   2716  C  CA  . THR A 1 378 ? -25.558 -36.324 26.617  1.00 22.50  ? 357 THR A CA  1 
ATOM   2717  C  C   . THR A 1 378 ? -24.763 -35.955 27.858  1.00 25.82  ? 357 THR A C   1 
ATOM   2718  O  O   . THR A 1 378 ? -25.285 -36.103 28.962  1.00 24.22  ? 357 THR A O   1 
ATOM   2719  C  CB  . THR A 1 378 ? -25.733 -37.852 26.574  1.00 23.33  ? 357 THR A CB  1 
ATOM   2720  O  OG1 . THR A 1 378 ? -24.441 -38.472 26.555  1.00 23.87  ? 357 THR A OG1 1 
ATOM   2721  C  CG2 . THR A 1 378 ? -26.486 -38.256 25.284  1.00 30.16  ? 357 THR A CG2 1 
ATOM   2722  N  N   . ILE A 1 379 ? -23.515 -35.514 27.717  1.00 22.55  ? 358 ILE A N   1 
ATOM   2723  C  CA  . ILE A 1 379 ? -22.681 -35.178 28.870  1.00 18.14  ? 358 ILE A CA  1 
ATOM   2724  C  C   . ILE A 1 379 ? -23.043 -33.750 29.304  1.00 21.86  ? 358 ILE A C   1 
ATOM   2725  O  O   . ILE A 1 379 ? -22.707 -32.780 28.620  1.00 19.84  ? 358 ILE A O   1 
ATOM   2726  C  CB  . ILE A 1 379 ? -21.190 -35.293 28.528  1.00 24.12  ? 358 ILE A CB  1 
ATOM   2727  C  CG1 . ILE A 1 379 ? -20.825 -36.678 27.946  1.00 20.88  ? 358 ILE A CG1 1 
ATOM   2728  C  CG2 . ILE A 1 379 ? -20.336 -34.918 29.737  1.00 26.53  ? 358 ILE A CG2 1 
ATOM   2729  C  CD1 . ILE A 1 379 ? -19.392 -36.741 27.342  1.00 25.21  ? 358 ILE A CD1 1 
ATOM   2730  N  N   . LYS A 1 380 ? -23.749 -33.616 30.422  1.00 22.94  ? 359 LYS A N   1 
ATOM   2731  C  CA  . LYS A 1 380 ? -24.341 -32.316 30.756  1.00 26.70  ? 359 LYS A CA  1 
ATOM   2732  C  C   . LYS A 1 380 ? -23.327 -31.177 30.919  1.00 22.10  ? 359 LYS A C   1 
ATOM   2733  O  O   . LYS A 1 380 ? -23.561 -30.091 30.364  1.00 21.64  ? 359 LYS A O   1 
ATOM   2734  C  CB  . LYS A 1 380 ? -25.208 -32.438 32.012  1.00 27.54  ? 359 LYS A CB  1 
ATOM   2735  C  CG  . LYS A 1 380 ? -25.998 -31.155 32.316  1.00 27.87  ? 359 LYS A CG  1 
ATOM   2736  C  CD  . LYS A 1 380 ? -27.027 -31.412 33.421  1.00 31.86  ? 359 LYS A CD  1 
ATOM   2737  C  CE  . LYS A 1 380 ? -28.001 -30.284 33.535  1.00 33.81  ? 359 LYS A CE  1 
ATOM   2738  N  NZ  . LYS A 1 380 ? -28.988 -30.370 32.432  1.00 41.43  ? 359 LYS A NZ  1 
ATOM   2739  N  N   . PRO A 1 381 ? -22.206 -31.341 31.624  1.00 23.03  ? 360 PRO A N   1 
ATOM   2740  C  CA  . PRO A 1 381 ? -21.258 -30.225 31.757  1.00 20.84  ? 360 PRO A CA  1 
ATOM   2741  C  C   . PRO A 1 381 ? -20.303 -30.067 30.584  1.00 23.16  ? 360 PRO A C   1 
ATOM   2742  O  O   . PRO A 1 381 ? -19.395 -29.224 30.668  1.00 19.93  ? 360 PRO A O   1 
ATOM   2743  C  CB  . PRO A 1 381 ? -20.475 -30.604 33.028  1.00 21.79  ? 360 PRO A CB  1 
ATOM   2744  C  CG  . PRO A 1 381 ? -20.352 -32.107 32.868  1.00 22.01  ? 360 PRO A CG  1 
ATOM   2745  C  CD  . PRO A 1 381 ? -21.771 -32.512 32.420  1.00 19.28  ? 360 PRO A CD  1 
ATOM   2746  N  N   . PHE A 1 382 ? -20.447 -30.854 29.504  1.00 16.84  ? 361 PHE A N   1 
ATOM   2747  C  CA  . PHE A 1 382 ? -19.534 -30.734 28.378  1.00 17.30  ? 361 PHE A CA  1 
ATOM   2748  C  C   . PHE A 1 382 ? -20.130 -29.666 27.477  1.00 16.75  ? 361 PHE A C   1 
ATOM   2749  O  O   . PHE A 1 382 ? -20.878 -29.974 26.545  1.00 19.12  ? 361 PHE A O   1 
ATOM   2750  C  CB  . PHE A 1 382 ? -19.379 -32.081 27.657  1.00 16.88  ? 361 PHE A CB  1 
ATOM   2751  C  CG  . PHE A 1 382 ? -18.370 -32.049 26.518  1.00 16.08  ? 361 PHE A CG  1 
ATOM   2752  C  CD1 . PHE A 1 382 ? -17.166 -31.358 26.677  1.00 17.14  ? 361 PHE A CD1 1 
ATOM   2753  C  CD2 . PHE A 1 382 ? -18.604 -32.776 25.355  1.00 17.75  ? 361 PHE A CD2 1 
ATOM   2754  C  CE1 . PHE A 1 382 ? -16.230 -31.330 25.652  1.00 18.07  ? 361 PHE A CE1 1 
ATOM   2755  C  CE2 . PHE A 1 382 ? -17.679 -32.769 24.311  1.00 18.62  ? 361 PHE A CE2 1 
ATOM   2756  C  CZ  . PHE A 1 382 ? -16.460 -32.045 24.478  1.00 17.71  ? 361 PHE A CZ  1 
ATOM   2757  N  N   . ILE A 1 383 ? -19.813 -28.394 27.771  1.00 20.18  ? 362 ILE A N   1 
ATOM   2758  C  CA  . ILE A 1 383 ? -20.481 -27.268 27.110  1.00 19.84  ? 362 ILE A CA  1 
ATOM   2759  C  C   . ILE A 1 383 ? -19.505 -26.326 26.406  1.00 21.05  ? 362 ILE A C   1 
ATOM   2760  O  O   . ILE A 1 383 ? -19.690 -25.090 26.474  1.00 19.75  ? 362 ILE A O   1 
ATOM   2761  C  CB  . ILE A 1 383 ? -21.324 -26.475 28.123  1.00 18.70  ? 362 ILE A CB  1 
ATOM   2762  C  CG1 . ILE A 1 383 ? -20.455 -25.913 29.276  1.00 19.36  ? 362 ILE A CG1 1 
ATOM   2763  C  CG2 . ILE A 1 383 ? -22.493 -27.318 28.659  1.00 20.61  ? 362 ILE A CG2 1 
ATOM   2764  C  CD1 . ILE A 1 383 ? -21.167 -24.723 29.991  1.00 20.83  ? 362 ILE A CD1 1 
ATOM   2765  N  N   . PRO A 1 384 ? -18.485 -26.816 25.685  1.00 17.47  ? 363 PRO A N   1 
ATOM   2766  C  CA  . PRO A 1 384 ? -17.574 -25.853 25.041  1.00 17.22  ? 363 PRO A CA  1 
ATOM   2767  C  C   . PRO A 1 384 ? -18.289 -24.935 24.074  1.00 19.42  ? 363 PRO A C   1 
ATOM   2768  O  O   . PRO A 1 384 ? -17.814 -23.822 23.827  1.00 20.31  ? 363 PRO A O   1 
ATOM   2769  C  CB  . PRO A 1 384 ? -16.568 -26.743 24.303  1.00 22.71  ? 363 PRO A CB  1 
ATOM   2770  C  CG  . PRO A 1 384 ? -17.376 -27.968 23.965  1.00 20.72  ? 363 PRO A CG  1 
ATOM   2771  C  CD  . PRO A 1 384 ? -18.233 -28.198 25.218  1.00 17.64  ? 363 PRO A CD  1 
ATOM   2772  N  N   . GLN A 1 385 ? -19.427 -25.376 23.514  1.00 18.71  ? 364 GLN A N   1 
ATOM   2773  C  CA  . GLN A 1 385 ? -20.154 -24.517 22.575  1.00 17.86  ? 364 GLN A CA  1 
ATOM   2774  C  C   . GLN A 1 385 ? -21.605 -24.343 23.035  1.00 19.45  ? 364 GLN A C   1 
ATOM   2775  O  O   . GLN A 1 385 ? -22.524 -24.215 22.213  1.00 18.43  ? 364 GLN A O   1 
ATOM   2776  C  CB  . GLN A 1 385 ? -20.032 -25.068 21.142  1.00 17.63  ? 364 GLN A CB  1 
ATOM   2777  C  CG  . GLN A 1 385 ? -18.510 -25.195 20.739  1.00 18.08  ? 364 GLN A CG  1 
ATOM   2778  C  CD  . GLN A 1 385 ? -18.151 -25.785 19.358  1.00 27.34  ? 364 GLN A CD  1 
ATOM   2779  O  OE1 . GLN A 1 385 ? -17.111 -26.399 19.236  1.00 24.59  ? 364 GLN A OE1 1 
ATOM   2780  N  NE2 . GLN A 1 385 ? -18.957 -25.555 18.336  1.00 17.10  ? 364 GLN A NE2 1 
ATOM   2781  N  N   . GLY A 1 386 ? -21.817 -24.412 24.346  1.00 18.68  ? 365 GLY A N   1 
ATOM   2782  C  CA  . GLY A 1 386 ? -23.107 -24.213 24.984  1.00 20.02  ? 365 GLY A CA  1 
ATOM   2783  C  C   . GLY A 1 386 ? -23.727 -25.525 25.448  1.00 18.91  ? 365 GLY A C   1 
ATOM   2784  O  O   . GLY A 1 386 ? -23.275 -26.628 25.116  1.00 20.62  ? 365 GLY A O   1 
ATOM   2785  N  N   . GLY A 1 387 ? -24.818 -25.383 26.198  1.00 18.37  ? 366 GLY A N   1 
ATOM   2786  C  CA  . GLY A 1 387 ? -25.490 -26.501 26.824  1.00 19.75  ? 366 GLY A CA  1 
ATOM   2787  C  C   . GLY A 1 387 ? -26.965 -26.591 26.441  1.00 22.41  ? 366 GLY A C   1 
ATOM   2788  O  O   . GLY A 1 387 ? -27.470 -25.842 25.601  1.00 20.22  ? 366 GLY A O   1 
ATOM   2789  N  N   . ALA A 1 388 ? -27.636 -27.553 27.058  1.00 22.51  ? 367 ALA A N   1 
ATOM   2790  C  CA  . ALA A 1 388 ? -29.059 -27.859 26.776  1.00 19.93  ? 367 ALA A CA  1 
ATOM   2791  C  C   . ALA A 1 388 ? -29.238 -28.241 25.300  1.00 25.80  ? 367 ALA A C   1 
ATOM   2792  O  O   . ALA A 1 388 ? -28.379 -28.914 24.711  1.00 24.00  ? 367 ALA A O   1 
ATOM   2793  C  CB  . ALA A 1 388 ? -29.917 -26.682 27.245  1.00 20.83  ? 367 ALA A CB  1 
ATOM   2794  N  N   . ASP A 1 389 ? -30.361 -27.870 24.666  1.00 19.12  ? 368 ASP A N   1 
ATOM   2795  C  CA  . ASP A 1 389 ? -30.776 -28.469 23.404  1.00 22.22  ? 368 ASP A CA  1 
ATOM   2796  C  C   . ASP A 1 389 ? -30.521 -27.511 22.241  1.00 21.06  ? 368 ASP A C   1 
ATOM   2797  O  O   . ASP A 1 389 ? -30.760 -26.306 22.356  1.00 21.94  ? 368 ASP A O   1 
ATOM   2798  C  CB  . ASP A 1 389 ? -32.267 -28.842 23.460  1.00 25.08  ? 368 ASP A CB  1 
ATOM   2799  C  CG  . ASP A 1 389 ? -32.723 -29.541 22.210  1.00 34.99  ? 368 ASP A CG  1 
ATOM   2800  O  OD1 . ASP A 1 389 ? -32.437 -30.741 22.079  1.00 39.19  ? 368 ASP A OD1 1 
ATOM   2801  O  OD2 . ASP A 1 389 ? -33.333 -28.891 21.339  1.00 36.72  ? 368 ASP A OD2 1 
ATOM   2802  N  N   . VAL A 1 390 ? -30.024 -28.056 21.127  1.00 21.04  ? 369 VAL A N   1 
ATOM   2803  C  CA  . VAL A 1 390 ? -29.698 -27.243 19.943  1.00 22.17  ? 369 VAL A CA  1 
ATOM   2804  C  C   . VAL A 1 390 ? -30.946 -26.626 19.294  1.00 27.32  ? 369 VAL A C   1 
ATOM   2805  O  O   . VAL A 1 390 ? -30.933 -25.461 18.888  1.00 21.87  ? 369 VAL A O   1 
ATOM   2806  C  CB  . VAL A 1 390 ? -28.914 -28.103 18.920  1.00 23.92  ? 369 VAL A CB  1 
ATOM   2807  C  CG1 . VAL A 1 390 ? -28.789 -27.402 17.592  1.00 23.98  ? 369 VAL A CG1 1 
ATOM   2808  C  CG2 . VAL A 1 390 ? -27.531 -28.431 19.424  1.00 22.97  ? 369 VAL A CG2 1 
ATOM   2809  N  N   . ARG A 1 391 ? -32.024 -27.392 19.114  1.00 27.00  ? 370 ARG A N   1 
ATOM   2810  C  CA  . ARG A 1 391 ? -33.120 -26.805 18.344  1.00 31.21  ? 370 ARG A CA  1 
ATOM   2811  C  C   . ARG A 1 391 ? -34.056 -25.945 19.174  1.00 26.77  ? 370 ARG A C   1 
ATOM   2812  O  O   . ARG A 1 391 ? -34.616 -24.968 18.655  1.00 33.97  ? 370 ARG A O   1 
ATOM   2813  C  CB  . ARG A 1 391 ? -33.916 -27.905 17.620  1.00 31.18  ? 370 ARG A CB  1 
ATOM   2814  C  CG  . ARG A 1 391 ? -33.139 -28.503 16.438  1.00 40.11  ? 370 ARG A CG  1 
ATOM   2815  C  CD  . ARG A 1 391 ? -34.027 -29.373 15.506  1.00 46.71  ? 370 ARG A CD  1 
ATOM   2816  N  NE  . ARG A 1 391 ? -33.249 -30.272 14.645  1.00 44.26  ? 370 ARG A NE  1 
ATOM   2817  C  CZ  . ARG A 1 391 ? -32.750 -31.435 15.046  1.00 52.59  ? 370 ARG A CZ  1 
ATOM   2818  N  NH1 . ARG A 1 391 ? -32.857 -31.838 16.309  1.00 42.06  ? 370 ARG A NH1 1 
ATOM   2819  N  NH2 . ARG A 1 391 ? -32.133 -32.217 14.159  1.00 42.05  ? 370 ARG A NH2 1 
ATOM   2820  N  N   . THR A 1 392 ? -34.231 -26.254 20.451  1.00 26.64  ? 371 THR A N   1 
ATOM   2821  C  CA  . THR A 1 392 ? -35.139 -25.484 21.289  1.00 26.83  ? 371 THR A CA  1 
ATOM   2822  C  C   . THR A 1 392 ? -34.447 -24.360 22.042  1.00 30.57  ? 371 THR A C   1 
ATOM   2823  O  O   . THR A 1 392 ? -35.131 -23.516 22.634  1.00 29.46  ? 371 THR A O   1 
ATOM   2824  C  CB  . THR A 1 392 ? -35.845 -26.409 22.298  1.00 32.96  ? 371 THR A CB  1 
ATOM   2825  O  OG1 . THR A 1 392 ? -34.875 -26.982 23.189  1.00 33.53  ? 371 THR A OG1 1 
ATOM   2826  C  CG2 . THR A 1 392 ? -36.603 -27.521 21.577  1.00 39.40  ? 371 THR A CG2 1 
ATOM   2827  N  N   . GLY A 1 393 ? -33.119 -24.320 22.043  1.00 25.06  ? 372 GLY A N   1 
ATOM   2828  C  CA  . GLY A 1 393 ? -32.433 -23.245 22.742  1.00 22.53  ? 372 GLY A CA  1 
ATOM   2829  C  C   . GLY A 1 393 ? -31.362 -22.585 21.897  1.00 19.77  ? 372 GLY A C   1 
ATOM   2830  O  O   . GLY A 1 393 ? -31.376 -22.686 20.669  1.00 21.84  ? 372 GLY A O   1 
ATOM   2831  N  N   . HIS A 1 394 ? -30.441 -21.859 22.544  1.00 20.34  ? 373 HIS A N   1 
ATOM   2832  C  CA  . HIS A 1 394 ? -29.428 -21.104 21.828  1.00 17.44  ? 373 HIS A CA  1 
ATOM   2833  C  C   . HIS A 1 394 ? -28.142 -21.889 21.634  1.00 19.19  ? 373 HIS A C   1 
ATOM   2834  O  O   . HIS A 1 394 ? -27.194 -21.340 21.086  1.00 20.62  ? 373 HIS A O   1 
ATOM   2835  C  CB  . HIS A 1 394 ? -29.104 -19.799 22.580  1.00 19.74  ? 373 HIS A CB  1 
ATOM   2836  C  CG  . HIS A 1 394 ? -30.086 -18.686 22.307  1.00 20.85  ? 373 HIS A CG  1 
ATOM   2837  N  ND1 . HIS A 1 394 ? -29.939 -17.803 21.260  1.00 20.96  ? 373 HIS A ND1 1 
ATOM   2838  C  CD2 . HIS A 1 394 ? -31.244 -18.350 22.923  1.00 21.87  ? 373 HIS A CD2 1 
ATOM   2839  C  CE1 . HIS A 1 394 ? -30.962 -16.956 21.246  1.00 18.38  ? 373 HIS A CE1 1 
ATOM   2840  N  NE2 . HIS A 1 394 ? -31.752 -17.246 22.264  1.00 22.77  ? 373 HIS A NE2 1 
ATOM   2841  N  N   . ARG A 1 395 ? -28.083 -23.151 22.075  1.00 20.20  ? 374 ARG A N   1 
ATOM   2842  C  CA  . ARG A 1 395 ? -26.851 -23.929 21.909  1.00 21.32  ? 374 ARG A CA  1 
ATOM   2843  C  C   . ARG A 1 395 ? -26.350 -23.914 20.461  1.00 19.24  ? 374 ARG A C   1 
ATOM   2844  O  O   . ARG A 1 395 ? -27.132 -23.950 19.500  1.00 19.49  ? 374 ARG A O   1 
ATOM   2845  C  CB  . ARG A 1 395 ? -27.082 -25.374 22.340  1.00 16.07  ? 374 ARG A CB  1 
ATOM   2846  C  CG  . ARG A 1 395 ? -25.822 -26.227 22.320  1.00 18.36  ? 374 ARG A CG  1 
ATOM   2847  C  CD  . ARG A 1 395 ? -26.148 -27.637 22.841  1.00 21.12  ? 374 ARG A CD  1 
ATOM   2848  N  NE  . ARG A 1 395 ? -24.967 -28.507 22.799  1.00 20.10  ? 374 ARG A NE  1 
ATOM   2849  C  CZ  . ARG A 1 395 ? -24.696 -29.432 23.712  1.00 21.13  ? 374 ARG A CZ  1 
ATOM   2850  N  NH1 . ARG A 1 395 ? -25.500 -29.645 24.745  1.00 20.77  ? 374 ARG A NH1 1 
ATOM   2851  N  NH2 . ARG A 1 395 ? -23.567 -30.134 23.607  1.00 20.86  ? 374 ARG A NH2 1 
ATOM   2852  N  N   . CYS A 1 396 ? -25.035 -23.904 20.318  1.00 17.94  ? 375 CYS A N   1 
ATOM   2853  C  CA  . CYS A 1 396 ? -24.399 -23.945 19.007  1.00 16.97  ? 375 CYS A CA  1 
ATOM   2854  C  C   . CYS A 1 396 ? -24.972 -25.089 18.164  1.00 21.31  ? 375 CYS A C   1 
ATOM   2855  O  O   . CYS A 1 396 ? -25.004 -26.230 18.628  1.00 20.94  ? 375 CYS A O   1 
ATOM   2856  C  CB  . CYS A 1 396 ? -22.888 -24.138 19.188  1.00 18.79  ? 375 CYS A CB  1 
ATOM   2857  S  SG  . CYS A 1 396 ? -21.938 -24.166 17.677  1.00 19.13  ? 375 CYS A SG  1 
ATOM   2858  N  N   . PRO A 1 397 ? -25.403 -24.837 16.930  1.00 18.53  ? 376 PRO A N   1 
ATOM   2859  C  CA  . PRO A 1 397 ? -25.745 -25.929 16.002  1.00 19.33  ? 376 PRO A CA  1 
ATOM   2860  C  C   . PRO A 1 397 ? -24.578 -26.434 15.164  1.00 17.49  ? 376 PRO A C   1 
ATOM   2861  O  O   . PRO A 1 397 ? -24.796 -27.272 14.280  1.00 21.03  ? 376 PRO A O   1 
ATOM   2862  C  CB  . PRO A 1 397 ? -26.795 -25.263 15.082  1.00 20.02  ? 376 PRO A CB  1 
ATOM   2863  C  CG  . PRO A 1 397 ? -26.206 -23.897 14.879  1.00 17.61  ? 376 PRO A CG  1 
ATOM   2864  C  CD  . PRO A 1 397 ? -25.625 -23.506 16.311  1.00 15.17  ? 376 PRO A CD  1 
ATOM   2865  N  N   . GLY A 1 398 ? -23.357 -25.949 15.406  1.00 17.63  ? 377 GLY A N   1 
ATOM   2866  C  CA  . GLY A 1 398 ? -22.242 -26.319 14.536  1.00 19.27  ? 377 GLY A CA  1 
ATOM   2867  C  C   . GLY A 1 398 ? -21.253 -27.250 15.183  1.00 20.01  ? 377 GLY A C   1 
ATOM   2868  O  O   . GLY A 1 398 ? -20.123 -27.330 14.717  1.00 21.27  ? 377 GLY A O   1 
ATOM   2869  N  N   . GLU A 1 399 ? -21.619 -27.933 16.273  1.00 17.57  ? 378 GLU A N   1 
ATOM   2870  C  CA  . GLU A 1 399 ? -20.620 -28.770 16.936  1.00 16.91  ? 378 GLU A CA  1 
ATOM   2871  C  C   . GLU A 1 399 ? -20.230 -29.964 16.068  1.00 19.50  ? 378 GLU A C   1 
ATOM   2872  O  O   . GLU A 1 399 ? -19.091 -30.439 16.146  1.00 20.29  ? 378 GLU A O   1 
ATOM   2873  C  CB  . GLU A 1 399 ? -21.142 -29.277 18.278  1.00 18.49  ? 378 GLU A CB  1 
ATOM   2874  C  CG  . GLU A 1 399 ? -21.425 -28.139 19.265  1.00 22.04  ? 378 GLU A CG  1 
ATOM   2875  C  CD  . GLU A 1 399 ? -21.553 -28.650 20.687  1.00 26.20  ? 378 GLU A CD  1 
ATOM   2876  O  OE1 . GLU A 1 399 ? -20.507 -28.767 21.386  1.00 28.84  ? 378 GLU A OE1 1 
ATOM   2877  O  OE2 . GLU A 1 399 ? -22.688 -28.934 21.123  1.00 26.75  ? 378 GLU A OE2 1 
ATOM   2878  N  N   . LYS A 1 400 ? -21.166 -30.490 15.275  1.00 19.55  ? 379 LYS A N   1 
ATOM   2879  C  CA  . LYS A 1 400 ? -20.800 -31.623 14.420  1.00 19.10  ? 379 LYS A CA  1 
ATOM   2880  C  C   . LYS A 1 400 ? -19.812 -31.176 13.348  1.00 24.74  ? 379 LYS A C   1 
ATOM   2881  O  O   . LYS A 1 400 ? -18.841 -31.893 13.028  1.00 21.30  ? 379 LYS A O   1 
ATOM   2882  C  CB  . LYS A 1 400 ? -22.050 -32.202 13.758  1.00 17.07  ? 379 LYS A CB  1 
ATOM   2883  C  CG  . LYS A 1 400 ? -23.039 -32.880 14.742  1.00 18.81  ? 379 LYS A CG  1 
ATOM   2884  C  CD  . LYS A 1 400 ? -24.348 -33.168 13.983  1.00 21.28  ? 379 LYS A CD  1 
ATOM   2885  C  CE  . LYS A 1 400 ? -25.352 -33.842 14.900  1.00 24.70  ? 379 LYS A CE  1 
ATOM   2886  N  NZ  . LYS A 1 400 ? -26.641 -34.160 14.184  1.00 24.25  ? 379 LYS A NZ  1 
ATOM   2887  N  N   . ILE A 1 401 ? -20.049 -29.986 12.780  1.00 20.58  ? 380 ILE A N   1 
ATOM   2888  C  CA  . ILE A 1 401 ? -19.093 -29.419 11.830  1.00 23.17  ? 380 ILE A CA  1 
ATOM   2889  C  C   . ILE A 1 401 ? -17.760 -29.195 12.519  1.00 20.50  ? 380 ILE A C   1 
ATOM   2890  O  O   . ILE A 1 401 ? -16.714 -29.526 11.972  1.00 19.29  ? 380 ILE A O   1 
ATOM   2891  C  CB  . ILE A 1 401 ? -19.616 -28.094 11.252  1.00 19.73  ? 380 ILE A CB  1 
ATOM   2892  C  CG1 . ILE A 1 401 ? -20.889 -28.305 10.406  1.00 20.64  ? 380 ILE A CG1 1 
ATOM   2893  C  CG2 . ILE A 1 401 ? -18.504 -27.347 10.470  1.00 18.80  ? 380 ILE A CG2 1 
ATOM   2894  C  CD1 . ILE A 1 401 ? -20.673 -29.062 9.200   1.00 30.62  ? 380 ILE A CD1 1 
ATOM   2895  N  N   . ALA A 1 402 ? -17.791 -28.583 13.714  1.00 20.48  ? 381 ALA A N   1 
ATOM   2896  C  CA  . ALA A 1 402 ? -16.549 -28.250 14.418  1.00 21.31  ? 381 ALA A CA  1 
ATOM   2897  C  C   . ALA A 1 402 ? -15.756 -29.499 14.788  1.00 20.95  ? 381 ALA A C   1 
ATOM   2898  O  O   . ALA A 1 402 ? -14.534 -29.541 14.610  1.00 19.44  ? 381 ALA A O   1 
ATOM   2899  C  CB  . ALA A 1 402 ? -16.849 -27.432 15.684  1.00 18.42  ? 381 ALA A CB  1 
ATOM   2900  N  N   . VAL A 1 403 ? -16.423 -30.530 15.312  1.00 18.68  ? 382 VAL A N   1 
ATOM   2901  C  CA  . VAL A 1 403 ? -15.693 -31.767 15.631  1.00 22.14  ? 382 VAL A CA  1 
ATOM   2902  C  C   . VAL A 1 403 ? -15.188 -32.461 14.358  1.00 21.02  ? 382 VAL A C   1 
ATOM   2903  O  O   . VAL A 1 403 ? -14.090 -33.051 14.350  1.00 20.87  ? 382 VAL A O   1 
ATOM   2904  C  CB  . VAL A 1 403 ? -16.587 -32.696 16.482  1.00 21.94  ? 382 VAL A CB  1 
ATOM   2905  C  CG1 . VAL A 1 403 ? -15.929 -34.094 16.643  1.00 25.55  ? 382 VAL A CG1 1 
ATOM   2906  C  CG2 . VAL A 1 403 ? -16.841 -32.047 17.837  1.00 25.97  ? 382 VAL A CG2 1 
ATOM   2907  N  N   . THR A 1 404 ? -15.946 -32.385 13.252  1.00 19.71  ? 383 THR A N   1 
ATOM   2908  C  CA  . THR A 1 404 ? -15.460 -32.921 11.974  1.00 21.23  ? 383 THR A CA  1 
ATOM   2909  C  C   . THR A 1 404 ? -14.180 -32.224 11.517  1.00 22.32  ? 383 THR A C   1 
ATOM   2910  O  O   . THR A 1 404 ? -13.186 -32.876 11.156  1.00 21.71  ? 383 THR A O   1 
ATOM   2911  C  CB  . THR A 1 404 ? -16.569 -32.804 10.918  1.00 20.77  ? 383 THR A CB  1 
ATOM   2912  O  OG1 . THR A 1 404 ? -17.696 -33.591 11.354  1.00 22.76  ? 383 THR A OG1 1 
ATOM   2913  C  CG2 . THR A 1 404 ? -16.084 -33.322 9.544   1.00 18.90  ? 383 THR A CG2 1 
ATOM   2914  N  N   . ALA A 1 405 ? -14.189 -30.894 11.513  1.00 18.40  ? 384 ALA A N   1 
ATOM   2915  C  CA  . ALA A 1 405 ? -12.997 -30.136 11.143  1.00 18.56  ? 384 ALA A CA  1 
ATOM   2916  C  C   . ALA A 1 405 ? -11.833 -30.423 12.098  1.00 19.50  ? 384 ALA A C   1 
ATOM   2917  O  O   . ALA A 1 405 ? -10.688 -30.641 11.666  1.00 20.70  ? 384 ALA A O   1 
ATOM   2918  C  CB  . ALA A 1 405 ? -13.338 -28.649 11.159  1.00 19.02  ? 384 ALA A CB  1 
ATOM   2919  N  N   . LEU A 1 406 ? -12.105 -30.369 13.410  1.00 20.29  ? 385 LEU A N   1 
ATOM   2920  C  CA  . LEU A 1 406 ? -11.035 -30.561 14.391  1.00 21.52  ? 385 LEU A CA  1 
ATOM   2921  C  C   . LEU A 1 406 ? -10.464 -31.970 14.317  1.00 18.77  ? 385 LEU A C   1 
ATOM   2922  O  O   . LEU A 1 406 ? -9.237  -32.151 14.416  1.00 21.83  ? 385 LEU A O   1 
ATOM   2923  C  CB  . LEU A 1 406 ? -11.542 -30.244 15.803  1.00 20.82  ? 385 LEU A CB  1 
ATOM   2924  C  CG  . LEU A 1 406 ? -10.498 -30.244 16.924  1.00 19.42  ? 385 LEU A CG  1 
ATOM   2925  C  CD1 . LEU A 1 406 ? -9.309  -29.332 16.572  1.00 17.41  ? 385 LEU A CD1 1 
ATOM   2926  C  CD2 . LEU A 1 406 ? -11.211 -29.795 18.249  1.00 19.82  ? 385 LEU A CD2 1 
ATOM   2927  N  N   . SER A 1 407 ? -11.318 -32.975 14.118  1.00 17.97  ? 386 SER A N   1 
ATOM   2928  C  CA  . SER A 1 407 ? -10.817 -34.350 13.993  1.00 20.09  ? 386 SER A CA  1 
ATOM   2929  C  C   . SER A 1 407 ? -9.947  -34.513 12.760  1.00 22.39  ? 386 SER A C   1 
ATOM   2930  O  O   . SER A 1 407 ? -8.947  -35.244 12.793  1.00 23.27  ? 386 SER A O   1 
ATOM   2931  C  CB  . SER A 1 407 ? -11.963 -35.362 13.917  1.00 19.43  ? 386 SER A CB  1 
ATOM   2932  O  OG  . SER A 1 407 ? -12.746 -35.336 15.073  1.00 31.18  ? 386 SER A OG  1 
ATOM   2933  N  N   . ALA A 1 408 ? -10.344 -33.890 11.642  1.00 20.53  ? 387 ALA A N   1 
ATOM   2934  C  CA  . ALA A 1 408 ? -9.502  -33.920 10.445  1.00 20.18  ? 387 ALA A CA  1 
ATOM   2935  C  C   . ALA A 1 408 ? -8.150  -33.299 10.740  1.00 24.41  ? 387 ALA A C   1 
ATOM   2936  O  O   . ALA A 1 408 ? -7.113  -33.837 10.338  1.00 23.26  ? 387 ALA A O   1 
ATOM   2937  C  CB  . ALA A 1 408 ? -10.171 -33.194 9.267   1.00 23.82  ? 387 ALA A CB  1 
ATOM   2938  N  N   . ALA A 1 409 ? -8.143  -32.179 11.474  1.00 18.84  ? 388 ALA A N   1 
ATOM   2939  C  CA  . ALA A 1 409 ? -6.881  -31.534 11.813  1.00 16.99  ? 388 ALA A CA  1 
ATOM   2940  C  C   . ALA A 1 409 ? -6.035  -32.435 12.699  1.00 23.17  ? 388 ALA A C   1 
ATOM   2941  O  O   . ALA A 1 409 ? -4.816  -32.531 12.497  1.00 20.51  ? 388 ALA A O   1 
ATOM   2942  C  CB  . ALA A 1 409 ? -7.148  -30.182 12.512  1.00 21.28  ? 388 ALA A CB  1 
ATOM   2943  N  N   . VAL A 1 410 ? -6.654  -33.060 13.716  1.00 18.66  ? 389 VAL A N   1 
ATOM   2944  C  CA  . VAL A 1 410 ? -5.909  -33.923 14.645  1.00 19.99  ? 389 VAL A CA  1 
ATOM   2945  C  C   . VAL A 1 410 ? -5.239  -35.065 13.894  1.00 23.78  ? 389 VAL A C   1 
ATOM   2946  O  O   . VAL A 1 410 ? -4.069  -35.402 14.150  1.00 21.10  ? 389 VAL A O   1 
ATOM   2947  C  CB  . VAL A 1 410 ? -6.846  -34.455 15.747  1.00 21.10  ? 389 VAL A CB  1 
ATOM   2948  C  CG1 . VAL A 1 410 ? -6.217  -35.634 16.457  1.00 23.15  ? 389 VAL A CG1 1 
ATOM   2949  C  CG2 . VAL A 1 410 ? -7.191  -33.313 16.766  1.00 19.77  ? 389 VAL A CG2 1 
ATOM   2950  N  N   . GLU A 1 411 ? -5.973  -35.696 12.971  1.00 19.90  ? 390 GLU A N   1 
ATOM   2951  C  CA  . GLU A 1 411 ? -5.399  -36.827 12.231  1.00 22.43  ? 390 GLU A CA  1 
ATOM   2952  C  C   . GLU A 1 411 ? -4.233  -36.395 11.359  1.00 26.46  ? 390 GLU A C   1 
ATOM   2953  O  O   . GLU A 1 411 ? -3.252  -37.139 11.205  1.00 26.30  ? 390 GLU A O   1 
ATOM   2954  C  CB  . GLU A 1 411 ? -6.472  -37.493 11.369  1.00 25.95  ? 390 GLU A CB  1 
ATOM   2955  C  CG  . GLU A 1 411 ? -7.367  -38.313 12.253  1.00 32.01  ? 390 GLU A CG  1 
ATOM   2956  C  CD  . GLU A 1 411 ? -8.256  -39.237 11.498  1.00 56.23  ? 390 GLU A CD  1 
ATOM   2957  O  OE1 . GLU A 1 411 ? -8.459  -39.021 10.284  1.00 67.64  ? 390 GLU A OE1 1 
ATOM   2958  O  OE2 . GLU A 1 411 ? -8.740  -40.192 12.133  1.00 40.84  ? 390 GLU A OE2 1 
ATOM   2959  N  N   . ALA A 1 412 ? -4.341  -35.229 10.723  1.00 21.35  ? 391 ALA A N   1 
ATOM   2960  C  CA  . ALA A 1 412 ? -3.253  -34.791 9.851   1.00 22.73  ? 391 ALA A CA  1 
ATOM   2961  C  C   . ALA A 1 412 ? -2.062  -34.317 10.675  1.00 20.65  ? 391 ALA A C   1 
ATOM   2962  O  O   . ALA A 1 412 ? -0.913  -34.616 10.334  1.00 22.83  ? 391 ALA A O   1 
ATOM   2963  C  CB  . ALA A 1 412 ? -3.745  -33.684 8.906   1.00 19.63  ? 391 ALA A CB  1 
ATOM   2964  N  N   . LEU A 1 413 ? -2.317  -33.612 11.784  1.00 20.25  ? 392 LEU A N   1 
ATOM   2965  C  CA  . LEU A 1 413 ? -1.226  -33.092 12.623  1.00 16.60  ? 392 LEU A CA  1 
ATOM   2966  C  C   . LEU A 1 413 ? -0.469  -34.208 13.327  1.00 19.99  ? 392 LEU A C   1 
ATOM   2967  O  O   . LEU A 1 413 ? 0.739   -34.070 13.609  1.00 22.36  ? 392 LEU A O   1 
ATOM   2968  C  CB  . LEU A 1 413 ? -1.766  -32.121 13.684  1.00 23.50  ? 392 LEU A CB  1 
ATOM   2969  C  CG  . LEU A 1 413 ? -2.165  -30.727 13.182  1.00 22.60  ? 392 LEU A CG  1 
ATOM   2970  C  CD1 . LEU A 1 413 ? -3.055  -30.070 14.265  1.00 23.69  ? 392 LEU A CD1 1 
ATOM   2971  C  CD2 . LEU A 1 413 ? -0.945  -29.848 12.846  1.00 23.73  ? 392 LEU A CD2 1 
ATOM   2972  N  N   . ALA A 1 414 ? -1.162  -35.306 13.639  1.00 20.16  ? 393 ALA A N   1 
ATOM   2973  C  CA  . ALA A 1 414 ? -0.533  -36.400 14.350  1.00 21.82  ? 393 ALA A CA  1 
ATOM   2974  C  C   . ALA A 1 414 ? 0.507   -37.126 13.513  1.00 21.19  ? 393 ALA A C   1 
ATOM   2975  O  O   . ALA A 1 414 ? 1.383   -37.766 14.084  1.00 20.81  ? 393 ALA A O   1 
ATOM   2976  C  CB  . ALA A 1 414 ? -1.599  -37.401 14.803  1.00 22.81  ? 393 ALA A CB  1 
ATOM   2977  N  N   . ARG A 1 415 ? 0.406   -37.082 12.187  1.00 18.47  ? 394 ARG A N   1 
ATOM   2978  C  CA  . ARG A 1 415 ? 1.288   -37.928 11.388  1.00 20.98  ? 394 ARG A CA  1 
ATOM   2979  C  C   . ARG A 1 415 ? 2.749   -37.659 11.738  1.00 22.61  ? 394 ARG A C   1 
ATOM   2980  O  O   . ARG A 1 415 ? 3.128   -36.511 11.983  1.00 20.99  ? 394 ARG A O   1 
ATOM   2981  C  CB  . ARG A 1 415 ? 1.054   -37.675 9.909   1.00 19.86  ? 394 ARG A CB  1 
ATOM   2982  C  CG  . ARG A 1 415 ? -0.315  -38.207 9.497   1.00 25.03  ? 394 ARG A CG  1 
ATOM   2983  C  CD  . ARG A 1 415 ? -0.491  -38.017 7.993   1.00 42.97  ? 394 ARG A CD  1 
ATOM   2984  N  NE  . ARG A 1 415 ? -0.253  -39.253 7.262   1.00 54.23  ? 394 ARG A NE  1 
ATOM   2985  C  CZ  . ARG A 1 415 ? -1.140  -40.236 7.178   1.00 75.51  ? 394 ARG A CZ  1 
ATOM   2986  N  NH1 . ARG A 1 415 ? -2.337  -40.139 7.747   1.00 65.39  ? 394 ARG A NH1 1 
ATOM   2987  N  NH2 . ARG A 1 415 ? -0.817  -41.347 6.517   1.00 62.64  ? 394 ARG A NH2 1 
ATOM   2988  N  N   . PRO A 1 416 ? 3.595   -38.690 11.771  1.00 21.94  ? 395 PRO A N   1 
ATOM   2989  C  CA  . PRO A 1 416 ? 4.938   -38.508 12.338  1.00 22.24  ? 395 PRO A CA  1 
ATOM   2990  C  C   . PRO A 1 416 ? 5.834   -37.596 11.515  1.00 25.11  ? 395 PRO A C   1 
ATOM   2991  O  O   . PRO A 1 416 ? 6.791   -37.042 12.057  1.00 25.82  ? 395 PRO A O   1 
ATOM   2992  C  CB  . PRO A 1 416 ? 5.479   -39.949 12.417  1.00 26.95  ? 395 PRO A CB  1 
ATOM   2993  C  CG  . PRO A 1 416 ? 4.716   -40.691 11.362  1.00 25.12  ? 395 PRO A CG  1 
ATOM   2994  C  CD  . PRO A 1 416 ? 3.308   -40.095 11.433  1.00 19.76  ? 395 PRO A CD  1 
ATOM   2995  N  N   . GLU A 1 417 ? 5.533   -37.360 10.250  1.00 18.62  ? 396 GLU A N   1 
ATOM   2996  C  CA  . GLU A 1 417 ? 6.375   -36.416 9.515   1.00 24.45  ? 396 GLU A CA  1 
ATOM   2997  C  C   . GLU A 1 417 ? 6.074   -34.958 9.863   1.00 28.41  ? 396 GLU A C   1 
ATOM   2998  O  O   . GLU A 1 417 ? 6.826   -34.071 9.453   1.00 23.65  ? 396 GLU A O   1 
ATOM   2999  C  CB  . GLU A 1 417 ? 6.200   -36.618 8.013   1.00 23.19  ? 396 GLU A CB  1 
ATOM   3000  C  CG  . GLU A 1 417 ? 4.795   -36.321 7.521   1.00 26.16  ? 396 GLU A CG  1 
ATOM   3001  C  CD  . GLU A 1 417 ? 3.895   -37.585 7.501   1.00 32.16  ? 396 GLU A CD  1 
ATOM   3002  O  OE1 . GLU A 1 417 ? 4.129   -38.536 8.300   1.00 27.52  ? 396 GLU A OE1 1 
ATOM   3003  O  OE2 . GLU A 1 417 ? 2.961   -37.627 6.672   1.00 28.19  ? 396 GLU A OE2 1 
ATOM   3004  N  N   . VAL A 1 418 ? 5.004   -34.680 10.612  1.00 22.05  ? 397 VAL A N   1 
ATOM   3005  C  CA  . VAL A 1 418 ? 4.706   -33.306 11.014  1.00 20.15  ? 397 VAL A CA  1 
ATOM   3006  C  C   . VAL A 1 418 ? 5.580   -32.973 12.216  1.00 25.93  ? 397 VAL A C   1 
ATOM   3007  O  O   . VAL A 1 418 ? 5.589   -33.705 13.209  1.00 26.53  ? 397 VAL A O   1 
ATOM   3008  C  CB  . VAL A 1 418 ? 3.214   -33.129 11.337  1.00 18.33  ? 397 VAL A CB  1 
ATOM   3009  C  CG1 . VAL A 1 418 ? 2.930   -31.684 11.887  1.00 24.13  ? 397 VAL A CG1 1 
ATOM   3010  C  CG2 . VAL A 1 418 ? 2.330   -33.449 10.095  1.00 21.12  ? 397 VAL A CG2 1 
ATOM   3011  N  N   . ARG A 1 419 ? 6.358   -31.882 12.121  1.00 21.53  ? 398 ARG A N   1 
ATOM   3012  C  CA  . ARG A 1 419 ? 7.264   -31.522 13.199  1.00 21.39  ? 398 ARG A CA  1 
ATOM   3013  C  C   . ARG A 1 419 ? 6.717   -30.252 13.843  1.00 23.10  ? 398 ARG A C   1 
ATOM   3014  O  O   . ARG A 1 419 ? 6.781   -29.178 13.241  1.00 25.82  ? 398 ARG A O   1 
ATOM   3015  C  CB  . ARG A 1 419 ? 8.698   -31.322 12.690  1.00 26.89  ? 398 ARG A CB  1 
ATOM   3016  C  CG  . ARG A 1 419 ? 9.243   -32.532 11.872  1.00 33.17  ? 398 ARG A CG  1 
ATOM   3017  C  CD  . ARG A 1 419 ? 9.107   -33.913 12.589  1.00 42.34  ? 398 ARG A CD  1 
ATOM   3018  N  NE  . ARG A 1 419 ? 9.367   -35.061 11.707  1.00 44.54  ? 398 ARG A NE  1 
ATOM   3019  C  CZ  . ARG A 1 419 ? 10.573  -35.406 11.262  1.00 50.49  ? 398 ARG A CZ  1 
ATOM   3020  N  NH1 . ARG A 1 419 ? 11.642  -34.681 11.549  1.00 44.87  ? 398 ARG A NH1 1 
ATOM   3021  N  NH2 . ARG A 1 419 ? 10.711  -36.511 10.511  1.00 40.95  ? 398 ARG A NH2 1 
ATOM   3022  N  N   . ILE A 1 420 ? 6.211   -30.386 15.066  1.00 21.09  ? 399 ILE A N   1 
ATOM   3023  C  CA  . ILE A 1 420 ? 5.555   -29.298 15.790  1.00 22.08  ? 399 ILE A CA  1 
ATOM   3024  C  C   . ILE A 1 420 ? 6.590   -28.632 16.680  1.00 27.01  ? 399 ILE A C   1 
ATOM   3025  O  O   . ILE A 1 420 ? 7.247   -29.300 17.494  1.00 22.64  ? 399 ILE A O   1 
ATOM   3026  C  CB  . ILE A 1 420 ? 4.367   -29.834 16.614  1.00 22.95  ? 399 ILE A CB  1 
ATOM   3027  C  CG1 . ILE A 1 420 ? 3.386   -30.549 15.686  1.00 24.44  ? 399 ILE A CG1 1 
ATOM   3028  C  CG2 . ILE A 1 420 ? 3.670   -28.726 17.443  1.00 22.22  ? 399 ILE A CG2 1 
ATOM   3029  C  CD1 . ILE A 1 420 ? 2.337   -31.439 16.473  1.00 25.80  ? 399 ILE A CD1 1 
ATOM   3030  N  N   . SER A 1 421 ? 6.735   -27.317 16.532  1.00 21.92  ? 400 SER A N   1 
ATOM   3031  C  CA  . SER A 1 421 ? 7.734   -26.591 17.323  1.00 22.34  ? 400 SER A CA  1 
ATOM   3032  C  C   . SER A 1 421 ? 7.445   -26.680 18.816  1.00 24.75  ? 400 SER A C   1 
ATOM   3033  O  O   . SER A 1 421 ? 6.300   -26.559 19.257  1.00 25.51  ? 400 SER A O   1 
ATOM   3034  C  CB  . SER A 1 421 ? 7.769   -25.127 16.924  1.00 23.39  ? 400 SER A CB  1 
ATOM   3035  O  OG  . SER A 1 421 ? 8.672   -24.457 17.802  1.00 25.62  ? 400 SER A OG  1 
ATOM   3036  N  N   . ALA A 1 422 ? 8.493   -26.869 19.606  1.00 26.32  ? 401 ALA A N   1 
ATOM   3037  C  CA  . ALA A 1 422 ? 8.332   -26.921 21.055  1.00 26.85  ? 401 ALA A CA  1 
ATOM   3038  C  C   . ALA A 1 422 ? 8.852   -25.668 21.756  1.00 30.14  ? 401 ALA A C   1 
ATOM   3039  O  O   . ALA A 1 422 ? 8.950   -25.672 22.987  1.00 24.52  ? 401 ALA A O   1 
ATOM   3040  C  CB  . ALA A 1 422 ? 9.016   -28.162 21.640  1.00 26.04  ? 401 ALA A CB  1 
ATOM   3041  N  N   . GLU A 1 423 ? 9.158   -24.596 21.018  1.00 21.06  ? 402 GLU A N   1 
ATOM   3042  C  CA  . GLU A 1 423 ? 9.653   -23.377 21.654  1.00 22.92  ? 402 GLU A CA  1 
ATOM   3043  C  C   . GLU A 1 423 ? 8.542   -22.709 22.463  1.00 21.64  ? 402 GLU A C   1 
ATOM   3044  O  O   . GLU A 1 423 ? 7.351   -22.945 22.241  1.00 21.91  ? 402 GLU A O   1 
ATOM   3045  C  CB  . GLU A 1 423 ? 10.233  -22.406 20.600  1.00 24.89  ? 402 GLU A CB  1 
ATOM   3046  C  CG  . GLU A 1 423 ? 11.249  -23.069 19.644  1.00 29.04  ? 402 GLU A CG  1 
ATOM   3047  C  CD  . GLU A 1 423 ? 12.543  -22.258 19.399  1.00 37.97  ? 402 GLU A CD  1 
ATOM   3048  O  OE1 . GLU A 1 423 ? 12.744  -21.166 20.009  1.00 29.56  ? 402 GLU A OE1 1 
ATOM   3049  O  OE2 . GLU A 1 423 ? 13.366  -22.737 18.560  1.00 41.95  ? 402 GLU A OE2 1 
ATOM   3050  N  N   . ALA A 1 424 ? 8.942   -21.883 23.442  1.00 21.38  ? 403 ALA A N   1 
ATOM   3051  C  CA  . ALA A 1 424 ? 7.962   -21.337 24.380  1.00 22.30  ? 403 ALA A CA  1 
ATOM   3052  C  C   . ALA A 1 424 ? 6.851   -20.542 23.691  1.00 23.77  ? 403 ALA A C   1 
ATOM   3053  O  O   . ALA A 1 424 ? 5.688   -20.623 24.107  1.00 21.96  ? 403 ALA A O   1 
ATOM   3054  C  CB  . ALA A 1 424 ? 8.654   -20.475 25.436  1.00 21.38  ? 403 ALA A CB  1 
ATOM   3055  N  N   . ILE A 1 425 ? 7.171   -19.767 22.654  1.00 22.76  ? 404 ILE A N   1 
ATOM   3056  C  CA  . ILE A 1 425 ? 6.112   -18.982 22.011  1.00 25.33  ? 404 ILE A CA  1 
ATOM   3057  C  C   . ILE A 1 425 ? 5.159   -19.846 21.202  1.00 29.00  ? 404 ILE A C   1 
ATOM   3058  O  O   . ILE A 1 425 ? 4.057   -19.395 20.862  1.00 24.96  ? 404 ILE A O   1 
ATOM   3059  C  CB  . ILE A 1 425 ? 6.657   -17.888 21.075  1.00 25.47  ? 404 ILE A CB  1 
ATOM   3060  C  CG1 . ILE A 1 425 ? 7.674   -18.476 20.097  1.00 25.24  ? 404 ILE A CG1 1 
ATOM   3061  C  CG2 . ILE A 1 425 ? 7.196   -16.680 21.903  1.00 27.38  ? 404 ILE A CG2 1 
ATOM   3062  C  CD1 . ILE A 1 425 ? 8.070   -17.505 18.941  1.00 27.66  ? 404 ILE A CD1 1 
ATOM   3063  N  N   . ASP A 1 426 ? 5.552   -21.075 20.877  1.00 22.67  ? 405 ASP A N   1 
ATOM   3064  C  CA  . ASP A 1 426 ? 4.671   -21.984 20.154  1.00 24.28  ? 405 ASP A CA  1 
ATOM   3065  C  C   . ASP A 1 426 ? 3.769   -22.785 21.057  1.00 25.00  ? 405 ASP A C   1 
ATOM   3066  O  O   . ASP A 1 426 ? 2.726   -23.233 20.597  1.00 24.58  ? 405 ASP A O   1 
ATOM   3067  C  CB  . ASP A 1 426 ? 5.474   -22.979 19.314  1.00 20.01  ? 405 ASP A CB  1 
ATOM   3068  C  CG  . ASP A 1 426 ? 6.343   -22.274 18.306  1.00 25.59  ? 405 ASP A CG  1 
ATOM   3069  O  OD1 . ASP A 1 426 ? 5.785   -21.626 17.392  1.00 24.68  ? 405 ASP A OD1 1 
ATOM   3070  O  OD2 . ASP A 1 426 ? 7.572   -22.304 18.470  1.00 25.61  ? 405 ASP A OD2 1 
ATOM   3071  N  N   . ILE A 1 427 ? 4.137   -22.978 22.319  1.00 22.28  ? 406 ILE A N   1 
ATOM   3072  C  CA  . ILE A 1 427 ? 3.489   -23.953 23.182  1.00 23.84  ? 406 ILE A CA  1 
ATOM   3073  C  C   . ILE A 1 427 ? 2.636   -23.280 24.245  1.00 30.19  ? 406 ILE A C   1 
ATOM   3074  O  O   . ILE A 1 427 ? 1.559   -23.774 24.584  1.00 32.53  ? 406 ILE A O   1 
ATOM   3075  C  CB  . ILE A 1 427 ? 4.545   -24.876 23.832  1.00 33.27  ? 406 ILE A CB  1 
ATOM   3076  C  CG1 . ILE A 1 427 ? 5.189   -25.773 22.772  1.00 30.30  ? 406 ILE A CG1 1 
ATOM   3077  C  CG2 . ILE A 1 427 ? 3.944   -25.673 24.988  1.00 33.31  ? 406 ILE A CG2 1 
ATOM   3078  C  CD1 . ILE A 1 427 ? 4.256   -26.849 22.214  1.00 27.54  ? 406 ILE A CD1 1 
ATOM   3079  N  N   . ASN A 1 428 ? 3.086   -22.149 24.760  1.00 25.67  ? 407 ASN A N   1 
ATOM   3080  C  CA  . ASN A 1 428 ? 2.380   -21.504 25.856  1.00 24.06  ? 407 ASN A CA  1 
ATOM   3081  C  C   . ASN A 1 428 ? 1.330   -20.512 25.340  1.00 24.39  ? 407 ASN A C   1 
ATOM   3082  O  O   . ASN A 1 428 ? 1.394   -20.013 24.220  1.00 26.29  ? 407 ASN A O   1 
ATOM   3083  C  CB  . ASN A 1 428 ? 3.382   -20.819 26.779  1.00 28.44  ? 407 ASN A CB  1 
ATOM   3084  C  CG  . ASN A 1 428 ? 4.275   -21.834 27.495  1.00 33.93  ? 407 ASN A CG  1 
ATOM   3085  O  OD1 . ASN A 1 428 ? 3.883   -22.416 28.518  1.00 30.49  ? 407 ASN A OD1 1 
ATOM   3086  N  ND2 . ASN A 1 428 ? 5.467   -22.080 26.937  1.00 29.11  ? 407 ASN A ND2 1 
ATOM   3087  N  N   . TYR A 1 429 ? 0.314   -20.274 26.165  1.00 25.74  ? 408 TYR A N   1 
ATOM   3088  C  CA  . TYR A 1 429 ? -0.729  -19.329 25.800  1.00 24.34  ? 408 TYR A CA  1 
ATOM   3089  C  C   . TYR A 1 429 ? -1.143  -18.577 27.054  1.00 23.04  ? 408 TYR A C   1 
ATOM   3090  O  O   . TYR A 1 429 ? -1.119  -19.119 28.161  1.00 24.05  ? 408 TYR A O   1 
ATOM   3091  C  CB  . TYR A 1 429 ? -1.956  -20.039 25.180  1.00 25.20  ? 408 TYR A CB  1 
ATOM   3092  C  CG  . TYR A 1 429 ? -2.484  -21.181 26.038  1.00 28.34  ? 408 TYR A CG  1 
ATOM   3093  C  CD1 . TYR A 1 429 ? -1.959  -22.465 25.929  1.00 24.57  ? 408 TYR A CD1 1 
ATOM   3094  C  CD2 . TYR A 1 429 ? -3.519  -20.977 26.942  1.00 23.43  ? 408 TYR A CD2 1 
ATOM   3095  C  CE1 . TYR A 1 429 ? -2.407  -23.491 26.727  1.00 24.16  ? 408 TYR A CE1 1 
ATOM   3096  C  CE2 . TYR A 1 429 ? -3.988  -22.012 27.733  1.00 21.91  ? 408 TYR A CE2 1 
ATOM   3097  C  CZ  . TYR A 1 429 ? -3.441  -23.264 27.613  1.00 27.72  ? 408 TYR A CZ  1 
ATOM   3098  O  OH  . TYR A 1 429 ? -3.915  -24.290 28.422  1.00 28.85  ? 408 TYR A OH  1 
ATOM   3099  N  N   . SER A 1 430 ? -1.562  -17.345 26.851  1.00 22.57  ? 409 SER A N   1 
ATOM   3100  C  CA  . SER A 1 430 ? -2.027  -16.481 27.931  1.00 22.80  ? 409 SER A CA  1 
ATOM   3101  C  C   . SER A 1 430 ? -3.493  -16.751 28.234  1.00 26.19  ? 409 SER A C   1 
ATOM   3102  O  O   . SER A 1 430 ? -4.289  -16.997 27.322  1.00 28.27  ? 409 SER A O   1 
ATOM   3103  C  CB  . SER A 1 430 ? -1.849  -15.015 27.523  1.00 30.76  ? 409 SER A CB  1 
ATOM   3104  O  OG  . SER A 1 430 ? -2.395  -14.127 28.485  1.00 27.30  ? 409 SER A OG  1 
ATOM   3105  N  N   . MET A 1 431 ? -3.856  -16.682 29.522  1.00 26.16  ? 410 MET A N   1 
ATOM   3106  C  CA  . MET A 1 431 ? -5.254  -16.775 29.930  1.00 22.82  ? 410 MET A CA  1 
ATOM   3107  C  C   . MET A 1 431 ? -5.911  -15.405 30.086  1.00 21.14  ? 410 MET A C   1 
ATOM   3108  O  O   . MET A 1 431 ? -7.092  -15.341 30.403  1.00 22.46  ? 410 MET A O   1 
ATOM   3109  C  CB  . MET A 1 431 ? -5.374  -17.541 31.259  1.00 26.29  ? 410 MET A CB  1 
ATOM   3110  C  CG  . MET A 1 431 ? -4.964  -18.995 31.198  1.00 28.75  ? 410 MET A CG  1 
ATOM   3111  S  SD  . MET A 1 431 ? -6.170  -19.945 30.242  1.00 35.70  ? 410 MET A SD  1 
ATOM   3112  C  CE  . MET A 1 431 ? -7.487  -20.345 31.410  1.00 27.22  ? 410 MET A CE  1 
ATOM   3113  N  N   . THR A 1 432 ? -5.179  -14.303 29.921  1.00 21.27  ? 411 THR A N   1 
ATOM   3114  C  CA  . THR A 1 432 ? -5.762  -13.006 30.232  1.00 23.52  ? 411 THR A CA  1 
ATOM   3115  C  C   . THR A 1 432 ? -6.185  -12.224 28.989  1.00 24.86  ? 411 THR A C   1 
ATOM   3116  O  O   . THR A 1 432 ? -6.641  -11.093 29.121  1.00 29.31  ? 411 THR A O   1 
ATOM   3117  C  CB  . THR A 1 432 ? -4.792  -12.201 31.098  1.00 26.29  ? 411 THR A CB  1 
ATOM   3118  O  OG1 . THR A 1 432 ? -3.522  -12.110 30.425  1.00 26.58  ? 411 THR A OG1 1 
ATOM   3119  C  CG2 . THR A 1 432 ? -4.556  -12.944 32.405  1.00 23.08  ? 411 THR A CG2 1 
ATOM   3120  N  N   . GLU A 1 433 ? -6.082  -12.806 27.792  1.00 23.24  ? 412 GLU A N   1 
ATOM   3121  C  CA  . GLU A 1 433 ? -6.568  -12.172 26.572  1.00 24.84  ? 412 GLU A CA  1 
ATOM   3122  C  C   . GLU A 1 433 ? -7.580  -13.110 25.900  1.00 23.85  ? 412 GLU A C   1 
ATOM   3123  O  O   . GLU A 1 433 ? -7.390  -14.325 25.882  1.00 24.89  ? 412 GLU A O   1 
ATOM   3124  C  CB  . GLU A 1 433 ? -5.402  -11.850 25.616  1.00 28.75  ? 412 GLU A CB  1 
ATOM   3125  C  CG  . GLU A 1 433 ? -4.504  -10.639 26.063  1.00 48.25  ? 412 GLU A CG  1 
ATOM   3126  C  CD  . GLU A 1 433 ? -3.524  -10.901 27.252  1.00 61.94  ? 412 GLU A CD  1 
ATOM   3127  O  OE1 . GLU A 1 433 ? -2.616  -11.780 27.162  1.00 42.15  ? 412 GLU A OE1 1 
ATOM   3128  O  OE2 . GLU A 1 433 ? -3.635  -10.178 28.280  1.00 53.79  ? 412 GLU A OE2 1 
ATOM   3129  N  N   . ILE A 1 434 ? -8.656  -12.540 25.363  1.00 22.09  ? 413 ILE A N   1 
ATOM   3130  C  CA  . ILE A 1 434 ? -9.686  -13.286 24.628  1.00 20.15  ? 413 ILE A CA  1 
ATOM   3131  C  C   . ILE A 1 434 ? -9.605  -12.900 23.149  1.00 27.48  ? 413 ILE A C   1 
ATOM   3132  O  O   . ILE A 1 434 ? -9.491  -11.709 22.832  1.00 24.43  ? 413 ILE A O   1 
ATOM   3133  C  CB  . ILE A 1 434 ? -11.076 -12.967 25.220  1.00 24.60  ? 413 ILE A CB  1 
ATOM   3134  C  CG1 . ILE A 1 434 ? -11.192 -13.606 26.625  1.00 30.25  ? 413 ILE A CG1 1 
ATOM   3135  C  CG2 . ILE A 1 434 ? -12.203 -13.408 24.280  1.00 29.14  ? 413 ILE A CG2 1 
ATOM   3136  C  CD1 . ILE A 1 434 ? -12.111 -12.935 27.578  1.00 31.34  ? 413 ILE A CD1 1 
ATOM   3137  N  N   . LEU A 1 435 ? -9.610  -13.895 22.244  1.00 19.52  ? 414 LEU A N   1 
ATOM   3138  C  CA  . LEU A 1 435 ? -9.527  -15.366 22.426  1.00 18.45  ? 414 LEU A CA  1 
ATOM   3139  C  C   . LEU A 1 435 ? -8.071  -15.723 22.739  1.00 27.23  ? 414 LEU A C   1 
ATOM   3140  O  O   . LEU A 1 435 ? -7.151  -14.925 22.499  1.00 27.86  ? 414 LEU A O   1 
ATOM   3141  C  CB  . LEU A 1 435 ? -9.974  -16.116 21.159  1.00 24.09  ? 414 LEU A CB  1 
ATOM   3142  C  CG  . LEU A 1 435 ? -11.430 -15.822 20.800  1.00 24.09  ? 414 LEU A CG  1 
ATOM   3143  C  CD1 . LEU A 1 435 ? -11.743 -16.374 19.449  1.00 18.35  ? 414 LEU A CD1 1 
ATOM   3144  C  CD2 . LEU A 1 435 ? -12.360 -16.483 21.852  1.00 20.15  ? 414 LEU A CD2 1 
ATOM   3145  N  N   . ALA A 1 436 ? -7.872  -16.920 23.276  1.00 21.84  ? 415 ALA A N   1 
ATOM   3146  C  CA  . ALA A 1 436 ? -6.544  -17.423 23.605  1.00 22.34  ? 415 ALA A CA  1 
ATOM   3147  C  C   . ALA A 1 436 ? -5.994  -18.260 22.452  1.00 22.84  ? 415 ALA A C   1 
ATOM   3148  O  O   . ALA A 1 436 ? -6.736  -18.988 21.781  1.00 24.67  ? 415 ALA A O   1 
ATOM   3149  C  CB  . ALA A 1 436 ? -6.624  -18.278 24.882  1.00 21.19  ? 415 ALA A CB  1 
ATOM   3150  N  N   . ARG A 1 437 ? -4.695  -18.146 22.223  1.00 24.34  ? 416 ARG A N   1 
ATOM   3151  C  CA  . ARG A 1 437 ? -3.947  -19.082 21.399  1.00 23.92  ? 416 ARG A CA  1 
ATOM   3152  C  C   . ARG A 1 437 ? -2.463  -18.872 21.669  1.00 24.72  ? 416 ARG A C   1 
ATOM   3153  O  O   . ARG A 1 437 ? -2.062  -17.811 22.154  1.00 25.55  ? 416 ARG A O   1 
ATOM   3154  C  CB  . ARG A 1 437 ? -4.262  -18.884 19.901  1.00 22.57  ? 416 ARG A CB  1 
ATOM   3155  C  CG  . ARG A 1 437 ? -3.983  -17.467 19.360  1.00 23.73  ? 416 ARG A CG  1 
ATOM   3156  C  CD  . ARG A 1 437 ? -4.097  -17.496 17.829  1.00 22.86  ? 416 ARG A CD  1 
ATOM   3157  N  NE  . ARG A 1 437 ? -3.791  -16.212 17.214  1.00 25.93  ? 416 ARG A NE  1 
ATOM   3158  C  CZ  . ARG A 1 437 ? -2.588  -15.845 16.791  1.00 35.71  ? 416 ARG A CZ  1 
ATOM   3159  N  NH1 . ARG A 1 437 ? -1.507  -16.587 17.025  1.00 31.41  ? 416 ARG A NH1 1 
ATOM   3160  N  NH2 . ARG A 1 437 ? -2.462  -14.702 16.125  1.00 32.37  ? 416 ARG A NH2 1 
ATOM   3161  N  N   . PRO A 1 438 ? -1.621  -19.848 21.342  1.00 27.63  ? 417 PRO A N   1 
ATOM   3162  C  CA  . PRO A 1 438 ? -0.180  -19.591 21.344  1.00 26.16  ? 417 PRO A CA  1 
ATOM   3163  C  C   . PRO A 1 438 ? 0.129   -18.396 20.474  1.00 31.20  ? 417 PRO A C   1 
ATOM   3164  O  O   . PRO A 1 438 ? -0.427  -18.246 19.380  1.00 23.91  ? 417 PRO A O   1 
ATOM   3165  C  CB  . PRO A 1 438 ? 0.417   -20.881 20.767  1.00 32.16  ? 417 PRO A CB  1 
ATOM   3166  C  CG  . PRO A 1 438 ? -0.572  -21.886 21.058  1.00 22.67  ? 417 PRO A CG  1 
ATOM   3167  C  CD  . PRO A 1 438 ? -1.930  -21.228 20.948  1.00 22.84  ? 417 PRO A CD  1 
ATOM   3168  N  N   . LYS A 1 439 ? 1.035   -17.544 20.973  1.00 28.84  ? 418 LYS A N   1 
ATOM   3169  C  CA  . LYS A 1 439 ? 1.335   -16.289 20.309  1.00 30.83  ? 418 LYS A CA  1 
ATOM   3170  C  C   . LYS A 1 439 ? 1.811   -16.514 18.892  1.00 31.49  ? 418 LYS A C   1 
ATOM   3171  O  O   . LYS A 1 439 ? 1.491   -15.729 17.998  1.00 31.73  ? 418 LYS A O   1 
ATOM   3172  C  CB  . LYS A 1 439 ? 2.401   -15.503 21.101  1.00 32.73  ? 418 LYS A CB  1 
ATOM   3173  C  CG  . LYS A 1 439 ? 1.868   -14.871 22.399  1.00 54.32  ? 418 LYS A CG  1 
ATOM   3174  C  CD  . LYS A 1 439 ? 2.928   -14.016 23.109  1.00 63.55  ? 418 LYS A CD  1 
ATOM   3175  C  CE  . LYS A 1 439 ? 2.322   -13.132 24.217  1.00 60.29  ? 418 LYS A CE  1 
ATOM   3176  N  NZ  . LYS A 1 439 ? 1.670   -13.904 25.304  1.00 43.30  ? 418 LYS A NZ  1 
ATOM   3177  N  N   . SER A 1 440 ? 2.596   -17.582 18.663  1.00 25.50  ? 419 SER A N   1 
ATOM   3178  C  CA  . SER A 1 440 ? 3.144   -17.785 17.333  1.00 26.62  ? 419 SER A CA  1 
ATOM   3179  C  C   . SER A 1 440 ? 2.119   -18.326 16.347  1.00 26.28  ? 419 SER A C   1 
ATOM   3180  O  O   . SER A 1 440 ? 2.356   -18.253 15.136  1.00 25.28  ? 419 SER A O   1 
ATOM   3181  C  CB  . SER A 1 440 ? 4.319   -18.749 17.386  1.00 27.94  ? 419 SER A CB  1 
ATOM   3182  O  OG  . SER A 1 440 ? 3.831   -20.063 17.611  1.00 25.56  ? 419 SER A OG  1 
ATOM   3183  N  N   . GLY A 1 441 ? 0.997   -18.851 16.832  1.00 28.07  ? 420 GLY A N   1 
ATOM   3184  C  CA  . GLY A 1 441 ? 0.089   -19.635 16.010  1.00 25.16  ? 420 GLY A CA  1 
ATOM   3185  C  C   . GLY A 1 441 ? 0.433   -21.109 15.932  1.00 24.69  ? 420 GLY A C   1 
ATOM   3186  O  O   . GLY A 1 441 ? -0.353  -21.881 15.366  1.00 22.06  ? 420 GLY A O   1 
ATOM   3187  N  N   . VAL A 1 442 ? 1.584   -21.506 16.486  1.00 20.58  ? 421 VAL A N   1 
ATOM   3188  C  CA  . VAL A 1 442 ? 2.187   -22.843 16.483  1.00 18.53  ? 421 VAL A CA  1 
ATOM   3189  C  C   . VAL A 1 442 ? 2.883   -23.088 15.153  1.00 24.74  ? 421 VAL A C   1 
ATOM   3190  O  O   . VAL A 1 442 ? 2.247   -23.382 14.131  1.00 21.36  ? 421 VAL A O   1 
ATOM   3191  C  CB  . VAL A 1 442 ? 1.211   -24.003 16.783  1.00 20.99  ? 421 VAL A CB  1 
ATOM   3192  C  CG1 . VAL A 1 442 ? 2.023   -25.300 17.017  1.00 23.10  ? 421 VAL A CG1 1 
ATOM   3193  C  CG2 . VAL A 1 442 ? 0.352   -23.691 18.029  1.00 22.02  ? 421 VAL A CG2 1 
ATOM   3194  N  N   . ARG A 1 443 ? 4.208   -22.978 15.161  1.00 21.46  ? 422 ARG A N   1 
ATOM   3195  C  CA  . ARG A 1 443 ? 4.955   -23.192 13.938  1.00 23.50  ? 422 ARG A CA  1 
ATOM   3196  C  C   . ARG A 1 443 ? 5.161   -24.679 13.711  1.00 22.80  ? 422 ARG A C   1 
ATOM   3197  O  O   . ARG A 1 443 ? 5.331   -25.447 14.657  1.00 24.61  ? 422 ARG A O   1 
ATOM   3198  C  CB  . ARG A 1 443 ? 6.284   -22.453 14.004  1.00 20.88  ? 422 ARG A CB  1 
ATOM   3199  C  CG  . ARG A 1 443 ? 6.053   -20.943 13.928  1.00 25.75  ? 422 ARG A CG  1 
ATOM   3200  C  CD  . ARG A 1 443 ? 7.323   -20.150 14.224  1.00 28.17  ? 422 ARG A CD  1 
ATOM   3201  N  NE  . ARG A 1 443 ? 7.795   -20.387 15.586  1.00 26.90  ? 422 ARG A NE  1 
ATOM   3202  C  CZ  . ARG A 1 443 ? 9.020   -20.074 15.987  1.00 31.43  ? 422 ARG A CZ  1 
ATOM   3203  N  NH1 . ARG A 1 443 ? 9.875   -19.464 15.175  1.00 28.84  ? 422 ARG A NH1 1 
ATOM   3204  N  NH2 . ARG A 1 443 ? 9.420   -20.435 17.206  1.00 24.64  ? 422 ARG A NH2 1 
ATOM   3205  N  N   . VAL A 1 444 ? 5.120   -25.080 12.443  1.00 21.58  ? 423 VAL A N   1 
ATOM   3206  C  CA  . VAL A 1 444 ? 5.175   -26.486 12.066  1.00 23.83  ? 423 VAL A CA  1 
ATOM   3207  C  C   . VAL A 1 444 ? 5.917   -26.575 10.752  1.00 22.86  ? 423 VAL A C   1 
ATOM   3208  O  O   . VAL A 1 444 ? 5.914   -25.640 9.952   1.00 25.66  ? 423 VAL A O   1 
ATOM   3209  C  CB  . VAL A 1 444 ? 3.778   -27.143 11.858  1.00 23.92  ? 423 VAL A CB  1 
ATOM   3210  C  CG1 . VAL A 1 444 ? 3.182   -27.533 13.171  1.00 37.99  ? 423 VAL A CG1 1 
ATOM   3211  C  CG2 . VAL A 1 444 ? 2.851   -26.159 11.064  1.00 22.65  ? 423 VAL A CG2 1 
ATOM   3212  N  N   . THR A 1 445 ? 6.502   -27.738 10.511  1.00 21.69  ? 424 THR A N   1 
ATOM   3213  C  CA  . THR A 1 445 ? 7.016   -28.075 9.192   1.00 22.53  ? 424 THR A CA  1 
ATOM   3214  C  C   . THR A 1 445 ? 6.766   -29.553 8.966   1.00 27.91  ? 424 THR A C   1 
ATOM   3215  O  O   . THR A 1 445 ? 6.532   -30.312 9.903   1.00 27.23  ? 424 THR A O   1 
ATOM   3216  C  CB  . THR A 1 445 ? 8.517   -27.740 9.029   1.00 31.60  ? 424 THR A CB  1 
ATOM   3217  O  OG1 . THR A 1 445 ? 8.901   -27.930 7.655   1.00 29.48  ? 424 THR A OG1 1 
ATOM   3218  C  CG2 . THR A 1 445 ? 9.388   -28.628 9.912   1.00 28.18  ? 424 THR A CG2 1 
ATOM   3219  N  N   . VAL A 1 446 ? 6.771   -29.965 7.708   1.00 25.17  ? 425 VAL A N   1 
ATOM   3220  C  CA  . VAL A 1 446 ? 6.596   -31.372 7.379   1.00 22.78  ? 425 VAL A CA  1 
ATOM   3221  C  C   . VAL A 1 446 ? 7.911   -31.853 6.795   1.00 26.18  ? 425 VAL A C   1 
ATOM   3222  O  O   . VAL A 1 446 ? 8.461   -31.212 5.892   1.00 25.59  ? 425 VAL A O   1 
ATOM   3223  C  CB  . VAL A 1 446 ? 5.439   -31.609 6.403   1.00 21.80  ? 425 VAL A CB  1 
ATOM   3224  C  CG1 . VAL A 1 446 ? 5.501   -33.042 5.885   1.00 28.10  ? 425 VAL A CG1 1 
ATOM   3225  C  CG2 . VAL A 1 446 ? 4.101   -31.415 7.149   1.00 28.14  ? 425 VAL A CG2 1 
ATOM   3226  N  N   . ALA A 1 447 ? 8.453   -32.920 7.382   1.00 30.26  ? 426 ALA A N   1 
ATOM   3227  C  CA  . ALA A 1 447 ? 9.727   -33.446 6.916   1.00 29.94  ? 426 ALA A CA  1 
ATOM   3228  C  C   . ALA A 1 447 ? 9.580   -33.928 5.490   1.00 31.98  ? 426 ALA A C   1 
ATOM   3229  O  O   . ALA A 1 447 ? 8.562   -34.517 5.125   1.00 29.12  ? 426 ALA A O   1 
ATOM   3230  C  CB  . ALA A 1 447 ? 10.200  -34.597 7.808   1.00 34.12  ? 426 ALA A CB  1 
ATOM   3231  N  N   . SER A 1 448 ? 10.611  -33.688 4.683   1.00 35.18  ? 427 SER A N   1 
ATOM   3232  C  CA  . SER A 1 448 ? 10.582  -34.051 3.278   1.00 52.43  ? 427 SER A CA  1 
ATOM   3233  C  C   . SER A 1 448 ? 11.944  -34.595 2.865   1.00 54.52  ? 427 SER A C   1 
ATOM   3234  O  O   . SER A 1 448 ? 12.970  -34.259 3.462   1.00 45.99  ? 427 SER A O   1 
ATOM   3235  C  CB  . SER A 1 448 ? 10.198  -32.843 2.405   1.00 46.51  ? 427 SER A CB  1 
ATOM   3236  O  OG  . SER A 1 448 ? 10.235  -33.179 1.037   1.00 50.14  ? 427 SER A OG  1 
ATOM   3237  N  N   . SER A 1 449 ? 11.939  -35.448 1.843   1.00 53.66  ? 428 SER A N   1 
ATOM   3238  C  CA  . SER A 1 449 ? 13.179  -35.927 1.220   1.00 61.98  ? 428 SER A CA  1 
ATOM   3239  C  C   . SER A 1 449 ? 13.575  -35.031 0.042   1.00 57.63  ? 428 SER A C   1 
ATOM   3240  O  O   . SER A 1 449 ? 12.710  -34.565 -0.712  1.00 64.66  ? 428 SER A O   1 
ATOM   3241  C  CB  . SER A 1 449 ? 13.027  -37.388 0.754   1.00 54.90  ? 428 SER A CB  1 
ATOM   3242  O  OG  . SER A 1 449 ? 12.040  -37.523 -0.266  1.00 63.14  ? 428 SER A OG  1 
ATOM   3243  N  N   . ASN B 1 29  ? -53.032 -8.167  12.657  1.00 60.40  ? 8   ASN B N   1 
ATOM   3244  C  CA  . ASN B 1 29  ? -53.395 -8.264  11.246  1.00 57.53  ? 8   ASN B CA  1 
ATOM   3245  C  C   . ASN B 1 29  ? -52.988 -6.995  10.446  1.00 54.34  ? 8   ASN B C   1 
ATOM   3246  O  O   . ASN B 1 29  ? -52.187 -7.106  9.524   1.00 57.15  ? 8   ASN B O   1 
ATOM   3247  C  CB  . ASN B 1 29  ? -54.901 -8.575  11.099  1.00 56.87  ? 8   ASN B CB  1 
ATOM   3248  C  CG  . ASN B 1 29  ? -55.365 -8.602  9.648   1.00 71.60  ? 8   ASN B CG  1 
ATOM   3249  O  OD1 . ASN B 1 29  ? -54.636 -9.045  8.754   1.00 75.47  ? 8   ASN B OD1 1 
ATOM   3250  N  ND2 . ASN B 1 29  ? -56.589 -8.123  9.408   1.00 64.48  ? 8   ASN B ND2 1 
ATOM   3251  N  N   . PRO B 1 30  ? -53.501 -5.804  10.783  1.00 47.12  ? 9   PRO B N   1 
ATOM   3252  C  CA  . PRO B 1 30  ? -53.125 -4.611  10.003  1.00 40.42  ? 9   PRO B CA  1 
ATOM   3253  C  C   . PRO B 1 30  ? -51.638 -4.310  10.137  1.00 37.35  ? 9   PRO B C   1 
ATOM   3254  O  O   . PRO B 1 30  ? -51.109 -4.194  11.243  1.00 30.23  ? 9   PRO B O   1 
ATOM   3255  C  CB  . PRO B 1 30  ? -53.972 -3.495  10.625  1.00 39.61  ? 9   PRO B CB  1 
ATOM   3256  C  CG  . PRO B 1 30  ? -55.070 -4.183  11.310  1.00 47.78  ? 9   PRO B CG  1 
ATOM   3257  C  CD  . PRO B 1 30  ? -54.467 -5.449  11.838  1.00 45.57  ? 9   PRO B CD  1 
ATOM   3258  N  N   . ARG B 1 31  ? -50.964 -4.179  9.009   1.00 42.71  ? 10  ARG B N   1 
ATOM   3259  C  CA  . ARG B 1 31  ? -49.534 -3.915  9.006   1.00 37.70  ? 10  ARG B CA  1 
ATOM   3260  C  C   . ARG B 1 31  ? -49.244 -2.771  8.046   1.00 45.23  ? 10  ARG B C   1 
ATOM   3261  O  O   . ARG B 1 31  ? -50.046 -2.442  7.171   1.00 44.17  ? 10  ARG B O   1 
ATOM   3262  C  CB  . ARG B 1 31  ? -48.720 -5.164  8.614   1.00 46.50  ? 10  ARG B CB  1 
ATOM   3263  C  CG  . ARG B 1 31  ? -48.779 -6.322  9.621   1.00 52.07  ? 10  ARG B CG  1 
ATOM   3264  C  CD  . ARG B 1 31  ? -47.658 -7.360  9.362   1.00 60.36  ? 10  ARG B CD  1 
ATOM   3265  N  NE  . ARG B 1 31  ? -46.325 -6.767  9.464   1.00 68.25  ? 10  ARG B NE  1 
ATOM   3266  C  CZ  . ARG B 1 31  ? -45.436 -7.062  10.408  1.00 68.40  ? 10  ARG B CZ  1 
ATOM   3267  N  NH1 . ARG B 1 31  ? -45.668 -8.006  11.306  1.00 61.49  ? 10  ARG B NH1 1 
ATOM   3268  N  NH2 . ARG B 1 31  ? -44.288 -6.387  10.456  1.00 59.27  ? 10  ARG B NH2 1 
ATOM   3269  N  N   . VAL B 1 32  ? -48.092 -2.149  8.238   1.00 34.35  ? 11  VAL B N   1 
ATOM   3270  C  CA  . VAL B 1 32  ? -47.566 -1.159  7.318   1.00 31.14  ? 11  VAL B CA  1 
ATOM   3271  C  C   . VAL B 1 32  ? -46.156 -1.628  6.996   1.00 41.44  ? 11  VAL B C   1 
ATOM   3272  O  O   . VAL B 1 32  ? -45.361 -1.878  7.909   1.00 37.89  ? 11  VAL B O   1 
ATOM   3273  C  CB  . VAL B 1 32  ? -47.584 0.258   7.926   1.00 38.37  ? 11  VAL B CB  1 
ATOM   3274  C  CG1 . VAL B 1 32  ? -46.634 1.169   7.222   1.00 42.55  ? 11  VAL B CG1 1 
ATOM   3275  C  CG2 . VAL B 1 32  ? -48.996 0.857   7.853   1.00 36.51  ? 11  VAL B CG2 1 
ATOM   3276  N  N   . SER B 1 33  ? -45.860 -1.809  5.715   1.00 43.02  ? 12  SER B N   1 
ATOM   3277  C  CA  . SER B 1 33  ? -44.617 -2.483  5.376   1.00 41.90  ? 12  SER B CA  1 
ATOM   3278  C  C   . SER B 1 33  ? -43.427 -1.530  5.481   1.00 46.02  ? 12  SER B C   1 
ATOM   3279  O  O   . SER B 1 33  ? -43.562 -0.302  5.413   1.00 43.67  ? 12  SER B O   1 
ATOM   3280  C  CB  . SER B 1 33  ? -44.696 -3.077  3.970   1.00 43.02  ? 12  SER B CB  1 
ATOM   3281  O  OG  . SER B 1 33  ? -44.949 -2.055  3.023   1.00 59.13  ? 12  SER B OG  1 
ATOM   3282  N  N   . GLY B 1 34  ? -42.245 -2.119  5.651   1.00 41.30  ? 13  GLY B N   1 
ATOM   3283  C  CA  . GLY B 1 34  ? -41.005 -1.375  5.618   1.00 45.64  ? 13  GLY B CA  1 
ATOM   3284  C  C   . GLY B 1 34  ? -40.636 -0.813  6.977   1.00 41.97  ? 13  GLY B C   1 
ATOM   3285  O  O   . GLY B 1 34  ? -41.422 -0.807  7.925   1.00 51.08  ? 13  GLY B O   1 
ATOM   3286  N  N   . ASP B 1 35  ? -39.402 -0.336  7.072   1.00 52.69  ? 14  ASP B N   1 
ATOM   3287  C  CA  . ASP B 1 35  ? -38.969 0.331   8.289   1.00 41.28  ? 14  ASP B CA  1 
ATOM   3288  C  C   . ASP B 1 35  ? -39.408 1.788   8.229   1.00 41.74  ? 14  ASP B C   1 
ATOM   3289  O  O   . ASP B 1 35  ? -39.034 2.515   7.304   1.00 40.03  ? 14  ASP B O   1 
ATOM   3290  C  CB  . ASP B 1 35  ? -37.457 0.209   8.478   1.00 38.68  ? 14  ASP B CB  1 
ATOM   3291  C  CG  . ASP B 1 35  ? -36.998 0.722   9.851   1.00 50.22  ? 14  ASP B CG  1 
ATOM   3292  O  OD1 . ASP B 1 35  ? -36.908 1.953   10.004  1.00 52.03  ? 14  ASP B OD1 1 
ATOM   3293  O  OD2 . ASP B 1 35  ? -36.748 -0.098  10.784  1.00 46.47  ? 14  ASP B OD2 1 
ATOM   3294  N  N   . ARG B 1 36  ? -40.226 2.203   9.198   1.00 38.45  ? 15  ARG B N   1 
ATOM   3295  C  CA  . ARG B 1 36  ? -40.789 3.550   9.247   1.00 34.63  ? 15  ARG B CA  1 
ATOM   3296  C  C   . ARG B 1 36  ? -40.076 4.438   10.258  1.00 35.69  ? 15  ARG B C   1 
ATOM   3297  O  O   . ARG B 1 36  ? -40.647 5.445   10.693  1.00 34.13  ? 15  ARG B O   1 
ATOM   3298  C  CB  . ARG B 1 36  ? -42.281 3.485   9.578   1.00 32.18  ? 15  ARG B CB  1 
ATOM   3299  C  CG  . ARG B 1 36  ? -43.097 2.661   8.576   1.00 27.42  ? 15  ARG B CG  1 
ATOM   3300  C  CD  . ARG B 1 36  ? -42.965 3.242   7.199   1.00 44.98  ? 15  ARG B CD  1 
ATOM   3301  N  NE  . ARG B 1 36  ? -43.734 2.520   6.195   1.00 48.04  ? 15  ARG B NE  1 
ATOM   3302  C  CZ  . ARG B 1 36  ? -44.736 3.041   5.495   1.00 63.35  ? 15  ARG B CZ  1 
ATOM   3303  N  NH1 . ARG B 1 36  ? -45.213 4.252   5.758   1.00 56.11  ? 15  ARG B NH1 1 
ATOM   3304  N  NH2 . ARG B 1 36  ? -45.279 2.324   4.509   1.00 50.11  ? 15  ARG B NH2 1 
ATOM   3305  N  N   . THR B 1 37  ? -38.859 4.066   10.674  1.00 28.31  ? 16  THR B N   1 
ATOM   3306  C  CA  . THR B 1 37  ? -38.155 4.869   11.676  1.00 30.11  ? 16  THR B CA  1 
ATOM   3307  C  C   . THR B 1 37  ? -38.082 6.334   11.284  1.00 34.25  ? 16  THR B C   1 
ATOM   3308  O  O   . THR B 1 37  ? -38.312 7.209   12.121  1.00 32.79  ? 16  THR B O   1 
ATOM   3309  C  CB  . THR B 1 37  ? -36.745 4.335   11.916  1.00 35.22  ? 16  THR B CB  1 
ATOM   3310  O  OG1 . THR B 1 37  ? -36.817 2.944   12.245  1.00 33.03  ? 16  THR B OG1 1 
ATOM   3311  C  CG2 . THR B 1 37  ? -36.092 5.097   13.085  1.00 30.87  ? 16  THR B CG2 1 
ATOM   3312  N  N   . ILE B 1 38  ? -37.794 6.633   10.011  1.00 28.89  ? 17  ILE B N   1 
ATOM   3313  C  CA  . ILE B 1 38  ? -37.593 8.044   9.665   1.00 35.25  ? 17  ILE B CA  1 
ATOM   3314  C  C   . ILE B 1 38  ? -38.914 8.805   9.749   1.00 36.29  ? 17  ILE B C   1 
ATOM   3315  O  O   . ILE B 1 38  ? -38.937 10.007  10.029  1.00 33.08  ? 17  ILE B O   1 
ATOM   3316  C  CB  . ILE B 1 38  ? -36.947 8.186   8.271   1.00 41.25  ? 17  ILE B CB  1 
ATOM   3317  C  CG1 . ILE B 1 38  ? -35.613 7.431   8.226   1.00 52.00  ? 17  ILE B CG1 1 
ATOM   3318  C  CG2 . ILE B 1 38  ? -36.702 9.635   7.934   1.00 37.25  ? 17  ILE B CG2 1 
ATOM   3319  C  CD1 . ILE B 1 38  ? -34.695 7.698   9.425   1.00 48.52  ? 17  ILE B CD1 1 
ATOM   3320  N  N   . GLN B 1 39  ? -40.027 8.115   9.536   1.00 30.16  ? 18  GLN B N   1 
ATOM   3321  C  CA  . GLN B 1 39  ? -41.329 8.755   9.607   1.00 34.51  ? 18  GLN B CA  1 
ATOM   3322  C  C   . GLN B 1 39  ? -41.638 9.301   11.003  1.00 35.17  ? 18  GLN B C   1 
ATOM   3323  O  O   . GLN B 1 39  ? -42.458 10.211  11.128  1.00 37.24  ? 18  GLN B O   1 
ATOM   3324  C  CB  . GLN B 1 39  ? -42.392 7.750   9.129   1.00 33.20  ? 18  GLN B CB  1 
ATOM   3325  C  CG  . GLN B 1 39  ? -43.561 8.392   8.442   1.00 38.83  ? 18  GLN B CG  1 
ATOM   3326  C  CD  . GLN B 1 39  ? -44.568 7.390   7.918   1.00 38.63  ? 18  GLN B CD  1 
ATOM   3327  O  OE1 . GLN B 1 39  ? -44.207 6.353   7.363   1.00 40.23  ? 18  GLN B OE1 1 
ATOM   3328  N  NE2 . GLN B 1 39  ? -45.844 7.704   8.085   1.00 37.11  ? 18  GLN B NE2 1 
ATOM   3329  N  N   . PHE B 1 40  ? -40.989 8.793   12.059  1.00 37.70  ? 19  PHE B N   1 
ATOM   3330  C  CA  . PHE B 1 40  ? -41.204 9.371   13.381  1.00 38.93  ? 19  PHE B CA  1 
ATOM   3331  C  C   . PHE B 1 40  ? -40.751 10.822  13.432  1.00 39.99  ? 19  PHE B C   1 
ATOM   3332  O  O   . PHE B 1 40  ? -41.440 11.678  14.002  1.00 41.01  ? 19  PHE B O   1 
ATOM   3333  C  CB  . PHE B 1 40  ? -40.482 8.538   14.443  1.00 50.12  ? 19  PHE B CB  1 
ATOM   3334  C  CG  . PHE B 1 40  ? -40.369 9.219   15.784  1.00 55.77  ? 19  PHE B CG  1 
ATOM   3335  C  CD1 . PHE B 1 40  ? -41.365 9.069   16.737  1.00 46.13  ? 19  PHE B CD1 1 
ATOM   3336  C  CD2 . PHE B 1 40  ? -39.258 10.001  16.101  1.00 60.69  ? 19  PHE B CD2 1 
ATOM   3337  C  CE1 . PHE B 1 40  ? -41.266 9.698   17.972  1.00 50.57  ? 19  PHE B CE1 1 
ATOM   3338  C  CE2 . PHE B 1 40  ? -39.156 10.635  17.334  1.00 58.42  ? 19  PHE B CE2 1 
ATOM   3339  C  CZ  . PHE B 1 40  ? -40.161 10.473  18.272  1.00 45.94  ? 19  PHE B CZ  1 
ATOM   3340  N  N   . LEU B 1 41  ? -39.588 11.131  12.850  1.00 34.93  ? 20  LEU B N   1 
ATOM   3341  C  CA  . LEU B 1 41  ? -39.159 12.524  12.817  1.00 34.57  ? 20  LEU B CA  1 
ATOM   3342  C  C   . LEU B 1 41  ? -39.961 13.351  11.834  1.00 38.90  ? 20  LEU B C   1 
ATOM   3343  O  O   . LEU B 1 41  ? -40.139 14.554  12.048  1.00 46.72  ? 20  LEU B O   1 
ATOM   3344  C  CB  . LEU B 1 41  ? -37.685 12.646  12.428  1.00 46.95  ? 20  LEU B CB  1 
ATOM   3345  C  CG  . LEU B 1 41  ? -36.642 12.380  13.488  1.00 42.61  ? 20  LEU B CG  1 
ATOM   3346  C  CD1 . LEU B 1 41  ? -35.274 12.585  12.862  1.00 37.48  ? 20  LEU B CD1 1 
ATOM   3347  C  CD2 . LEU B 1 41  ? -36.853 13.303  14.703  1.00 41.24  ? 20  LEU B CD2 1 
ATOM   3348  N  N   . THR B 1 42  ? -40.393 12.765  10.714  1.00 33.41  ? 21  THR B N   1 
ATOM   3349  C  CA  . THR B 1 42  ? -41.088 13.606  9.756   1.00 30.34  ? 21  THR B CA  1 
ATOM   3350  C  C   . THR B 1 42  ? -42.544 13.825  10.155  1.00 33.18  ? 21  THR B C   1 
ATOM   3351  O  O   . THR B 1 42  ? -43.127 14.842  9.780   1.00 37.84  ? 21  THR B O   1 
ATOM   3352  C  CB  . THR B 1 42  ? -40.989 12.996  8.354   1.00 34.66  ? 21  THR B CB  1 
ATOM   3353  O  OG1 . THR B 1 42  ? -41.643 11.728  8.336   1.00 41.01  ? 21  THR B OG1 1 
ATOM   3354  C  CG2 . THR B 1 42  ? -39.548 12.762  7.997   1.00 35.64  ? 21  THR B CG2 1 
ATOM   3355  N  N   . ASP B 1 43  ? -43.155 12.875  10.871  1.00 25.51  ? 22  ASP B N   1 
ATOM   3356  C  CA  . ASP B 1 43  ? -44.586 12.931  11.204  1.00 23.05  ? 22  ASP B CA  1 
ATOM   3357  C  C   . ASP B 1 43  ? -44.891 13.364  12.627  1.00 26.50  ? 22  ASP B C   1 
ATOM   3358  O  O   . ASP B 1 43  ? -45.989 13.874  12.873  1.00 23.37  ? 22  ASP B O   1 
ATOM   3359  C  CB  . ASP B 1 43  ? -45.259 11.568  11.051  1.00 26.99  ? 22  ASP B CB  1 
ATOM   3360  C  CG  . ASP B 1 43  ? -45.441 11.158  9.612   1.00 45.83  ? 22  ASP B CG  1 
ATOM   3361  O  OD1 . ASP B 1 43  ? -44.737 11.714  8.732   1.00 43.90  ? 22  ASP B OD1 1 
ATOM   3362  O  OD2 . ASP B 1 43  ? -46.284 10.260  9.381   1.00 43.52  ? 22  ASP B OD2 1 
ATOM   3363  N  N   . GLY B 1 44  ? -44.005 13.091  13.576  1.00 23.93  ? 23  GLY B N   1 
ATOM   3364  C  CA  . GLY B 1 44  ? -44.235 13.552  14.946  1.00 24.02  ? 23  GLY B CA  1 
ATOM   3365  C  C   . GLY B 1 44  ? -45.530 12.996  15.526  1.00 24.46  ? 23  GLY B C   1 
ATOM   3366  O  O   . GLY B 1 44  ? -45.787 11.787  15.490  1.00 24.94  ? 23  GLY B O   1 
ATOM   3367  N  N   . TYR B 1 45  ? -46.369 13.897  16.060  1.00 22.14  ? 24  TYR B N   1 
ATOM   3368  C  CA  . TYR B 1 45  ? -47.653 13.501  16.658  1.00 24.70  ? 24  TYR B CA  1 
ATOM   3369  C  C   . TYR B 1 45  ? -48.628 12.885  15.645  1.00 23.62  ? 24  TYR B C   1 
ATOM   3370  O  O   . TYR B 1 45  ? -49.591 12.235  16.051  1.00 25.50  ? 24  TYR B O   1 
ATOM   3371  C  CB  . TYR B 1 45  ? -48.336 14.720  17.306  1.00 23.41  ? 24  TYR B CB  1 
ATOM   3372  C  CG  . TYR B 1 45  ? -47.536 15.254  18.464  1.00 20.04  ? 24  TYR B CG  1 
ATOM   3373  C  CD1 . TYR B 1 45  ? -47.691 14.722  19.719  1.00 21.12  ? 24  TYR B CD1 1 
ATOM   3374  C  CD2 . TYR B 1 45  ? -46.593 16.264  18.265  1.00 22.08  ? 24  TYR B CD2 1 
ATOM   3375  C  CE1 . TYR B 1 45  ? -46.905 15.201  20.811  1.00 19.00  ? 24  TYR B CE1 1 
ATOM   3376  C  CE2 . TYR B 1 45  ? -45.823 16.749  19.314  1.00 21.77  ? 24  TYR B CE2 1 
ATOM   3377  C  CZ  . TYR B 1 45  ? -45.996 16.232  20.585  1.00 22.38  ? 24  TYR B CZ  1 
ATOM   3378  O  OH  . TYR B 1 45  ? -45.211 16.720  21.620  1.00 19.57  ? 24  TYR B OH  1 
ATOM   3379  N  N   . LEU B 1 46  ? -48.409 13.092  14.348  1.00 21.69  ? 25  LEU B N   1 
ATOM   3380  C  CA  . LEU B 1 46  ? -49.277 12.521  13.322  1.00 21.45  ? 25  LEU B CA  1 
ATOM   3381  C  C   . LEU B 1 46  ? -48.925 11.073  12.978  1.00 23.75  ? 25  LEU B C   1 
ATOM   3382  O  O   . LEU B 1 46  ? -49.669 10.434  12.217  1.00 24.16  ? 25  LEU B O   1 
ATOM   3383  C  CB  . LEU B 1 46  ? -49.168 13.357  12.030  1.00 20.85  ? 25  LEU B CB  1 
ATOM   3384  C  CG  . LEU B 1 46  ? -49.402 14.845  12.180  1.00 26.52  ? 25  LEU B CG  1 
ATOM   3385  C  CD1 . LEU B 1 46  ? -49.398 15.462  10.763  1.00 26.97  ? 25  LEU B CD1 1 
ATOM   3386  C  CD2 . LEU B 1 46  ? -50.707 15.081  12.939  1.00 24.48  ? 25  LEU B CD2 1 
ATOM   3387  N  N   . LEU B 1 47  ? -47.816 10.546  13.510  1.00 23.14  ? 26  LEU B N   1 
ATOM   3388  C  CA  . LEU B 1 47  ? -47.372 9.210   13.116  1.00 23.66  ? 26  LEU B CA  1 
ATOM   3389  C  C   . LEU B 1 47  ? -48.436 8.147   13.361  1.00 22.92  ? 26  LEU B C   1 
ATOM   3390  O  O   . LEU B 1 47  ? -48.755 7.409   12.414  1.00 23.36  ? 26  LEU B O   1 
ATOM   3391  C  CB  . LEU B 1 47  ? -46.061 8.850   13.830  1.00 25.48  ? 26  LEU B CB  1 
ATOM   3392  C  CG  . LEU B 1 47  ? -45.519 7.474   13.414  1.00 26.18  ? 26  LEU B CG  1 
ATOM   3393  C  CD1 . LEU B 1 47  ? -45.291 7.446   11.874  1.00 32.30  ? 26  LEU B CD1 1 
ATOM   3394  C  CD2 . LEU B 1 47  ? -44.223 7.152   14.144  1.00 38.75  ? 26  LEU B CD2 1 
ATOM   3395  N  N   . PRO B 1 48  ? -49.031 8.008   14.566  1.00 24.14  ? 27  PRO B N   1 
ATOM   3396  C  CA  . PRO B 1 48  ? -49.970 6.889   14.756  1.00 25.73  ? 27  PRO B CA  1 
ATOM   3397  C  C   . PRO B 1 48  ? -51.180 6.976   13.846  1.00 27.27  ? 27  PRO B C   1 
ATOM   3398  O  O   . PRO B 1 48  ? -51.614 5.947   13.316  1.00 22.90  ? 27  PRO B O   1 
ATOM   3399  C  CB  . PRO B 1 48  ? -50.363 6.991   16.245  1.00 21.61  ? 27  PRO B CB  1 
ATOM   3400  C  CG  . PRO B 1 48  ? -49.129 7.671   16.905  1.00 22.10  ? 27  PRO B CG  1 
ATOM   3401  C  CD  . PRO B 1 48  ? -48.747 8.698   15.843  1.00 27.52  ? 27  PRO B CD  1 
ATOM   3402  N  N   . SER B 1 49  ? -51.752 8.166   13.651  1.00 21.48  ? 28  SER B N   1 
ATOM   3403  C  CA  . SER B 1 49  ? -52.938 8.204   12.804  1.00 22.39  ? 28  SER B CA  1 
ATOM   3404  C  C   . SER B 1 49  ? -52.577 8.068   11.325  1.00 24.29  ? 28  SER B C   1 
ATOM   3405  O  O   . SER B 1 49  ? -53.370 7.500   10.574  1.00 25.87  ? 28  SER B O   1 
ATOM   3406  C  CB  . SER B 1 49  ? -53.769 9.469   13.060  1.00 23.97  ? 28  SER B CB  1 
ATOM   3407  O  OG  . SER B 1 49  ? -53.051 10.644  12.763  1.00 25.97  ? 28  SER B OG  1 
ATOM   3408  N  N   . ASN B 1 50  ? -51.394 8.529   10.893  1.00 22.23  ? 29  ASN B N   1 
ATOM   3409  C  CA  . ASN B 1 50  ? -50.956 8.214   9.535   1.00 24.55  ? 29  ASN B CA  1 
ATOM   3410  C  C   . ASN B 1 50  ? -50.805 6.711   9.334   1.00 27.73  ? 29  ASN B C   1 
ATOM   3411  O  O   . ASN B 1 50  ? -51.139 6.181   8.265   1.00 30.05  ? 29  ASN B O   1 
ATOM   3412  C  CB  . ASN B 1 50  ? -49.624 8.891   9.220   1.00 26.97  ? 29  ASN B CB  1 
ATOM   3413  C  CG  . ASN B 1 50  ? -49.798 10.252  8.544   1.00 41.91  ? 29  ASN B CG  1 
ATOM   3414  O  OD1 . ASN B 1 50  ? -50.611 10.408  7.641   1.00 43.62  ? 29  ASN B OD1 1 
ATOM   3415  N  ND2 . ASN B 1 50  ? -49.041 11.237  8.997   1.00 41.34  ? 29  ASN B ND2 1 
ATOM   3416  N  N   . LEU B 1 51  ? -50.233 6.008   10.322  1.00 25.00  ? 30  LEU B N   1 
ATOM   3417  C  CA  . LEU B 1 51  ? -50.010 4.571   10.129  1.00 25.12  ? 30  LEU B CA  1 
ATOM   3418  C  C   . LEU B 1 51  ? -51.331 3.817   10.063  1.00 25.03  ? 30  LEU B C   1 
ATOM   3419  O  O   . LEU B 1 51  ? -51.504 2.917   9.226   1.00 25.93  ? 30  LEU B O   1 
ATOM   3420  C  CB  . LEU B 1 51  ? -49.112 4.006   11.243  1.00 26.82  ? 30  LEU B CB  1 
ATOM   3421  C  CG  . LEU B 1 51  ? -47.663 4.507   11.160  1.00 28.42  ? 30  LEU B CG  1 
ATOM   3422  C  CD1 . LEU B 1 51  ? -46.846 4.036   12.327  1.00 34.25  ? 30  LEU B CD1 1 
ATOM   3423  C  CD2 . LEU B 1 51  ? -47.004 4.037   9.858   1.00 26.83  ? 30  LEU B CD2 1 
ATOM   3424  N  N   . ARG B 1 52  ? -52.269 4.148   10.951  1.00 25.34  ? 31  ARG B N   1 
ATOM   3425  C  CA  . ARG B 1 52  ? -53.586 3.524   10.890  1.00 26.56  ? 31  ARG B CA  1 
ATOM   3426  C  C   . ARG B 1 52  ? -54.245 3.770   9.539   1.00 25.93  ? 31  ARG B C   1 
ATOM   3427  O  O   . ARG B 1 52  ? -54.847 2.854   8.963   1.00 30.45  ? 31  ARG B O   1 
ATOM   3428  C  CB  . ARG B 1 52  ? -54.477 4.028   12.029  1.00 29.93  ? 31  ARG B CB  1 
ATOM   3429  C  CG  . ARG B 1 52  ? -54.063 3.508   13.433  1.00 26.93  ? 31  ARG B CG  1 
ATOM   3430  C  CD  . ARG B 1 52  ? -55.182 3.857   14.450  1.00 25.67  ? 31  ARG B CD  1 
ATOM   3431  N  NE  . ARG B 1 52  ? -55.160 5.275   14.777  1.00 31.92  ? 31  ARG B NE  1 
ATOM   3432  C  CZ  . ARG B 1 52  ? -54.451 5.799   15.771  1.00 25.61  ? 31  ARG B CZ  1 
ATOM   3433  N  NH1 . ARG B 1 52  ? -53.683 5.046   16.553  1.00 28.40  ? 31  ARG B NH1 1 
ATOM   3434  N  NH2 . ARG B 1 52  ? -54.532 7.109   16.004  1.00 28.93  ? 31  ARG B NH2 1 
ATOM   3435  N  N   . LYS B 1 53  ? -54.118 4.988   8.994   1.00 27.02  ? 32  LYS B N   1 
ATOM   3436  C  CA  . LYS B 1 53  ? -54.711 5.239   7.689   1.00 29.33  ? 32  LYS B CA  1 
ATOM   3437  C  C   . LYS B 1 53  ? -53.998 4.415   6.620   1.00 29.51  ? 32  LYS B C   1 
ATOM   3438  O  O   . LYS B 1 53  ? -54.644 3.781   5.782   1.00 29.86  ? 32  LYS B O   1 
ATOM   3439  C  CB  . LYS B 1 53  ? -54.655 6.728   7.346   1.00 31.66  ? 32  LYS B CB  1 
ATOM   3440  C  CG  . LYS B 1 53  ? -55.117 7.019   5.924   1.00 32.81  ? 32  LYS B CG  1 
ATOM   3441  C  CD  . LYS B 1 53  ? -54.899 8.473   5.541   1.00 33.76  ? 32  LYS B CD  1 
ATOM   3442  C  CE  . LYS B 1 53  ? -55.175 8.655   4.043   1.00 53.21  ? 32  LYS B CE  1 
ATOM   3443  N  NZ  . LYS B 1 53  ? -55.082 10.085  3.612   1.00 53.85  ? 32  LYS B NZ  1 
ATOM   3444  N  N   . THR B 1 54  ? -52.660 4.374   6.671   1.00 25.76  ? 33  THR B N   1 
ATOM   3445  C  CA  . THR B 1 54  ? -51.915 3.653   5.641   1.00 31.21  ? 33  THR B CA  1 
ATOM   3446  C  C   . THR B 1 54  ? -52.208 2.165   5.715   1.00 35.06  ? 33  THR B C   1 
ATOM   3447  O  O   . THR B 1 54  ? -52.222 1.487   4.686   1.00 32.32  ? 33  THR B O   1 
ATOM   3448  C  CB  . THR B 1 54  ? -50.412 3.925   5.779   1.00 35.14  ? 33  THR B CB  1 
ATOM   3449  O  OG1 . THR B 1 54  ? -50.138 5.292   5.464   1.00 32.87  ? 33  THR B OG1 1 
ATOM   3450  C  CG2 . THR B 1 54  ? -49.575 3.025   4.846   1.00 32.04  ? 33  THR B CG2 1 
ATOM   3451  N  N   . ALA B 1 55  ? -52.465 1.644   6.917   1.00 30.43  ? 34  ALA B N   1 
ATOM   3452  C  CA  . ALA B 1 55  ? -52.789 0.237   7.071   1.00 30.73  ? 34  ALA B CA  1 
ATOM   3453  C  C   . ALA B 1 55  ? -54.184 -0.101  6.570   1.00 31.78  ? 34  ALA B C   1 
ATOM   3454  O  O   . ALA B 1 55  ? -54.536 -1.280  6.560   1.00 33.22  ? 34  ALA B O   1 
ATOM   3455  C  CB  . ALA B 1 55  ? -52.667 -0.204  8.531   1.00 30.68  ? 34  ALA B CB  1 
ATOM   3456  N  N   . GLY B 1 56  ? -54.975 0.881   6.162   1.00 32.83  ? 35  GLY B N   1 
ATOM   3457  C  CA  . GLY B 1 56  ? -56.332 0.625   5.719   1.00 27.78  ? 35  GLY B CA  1 
ATOM   3458  C  C   . GLY B 1 56  ? -57.389 0.592   6.803   1.00 34.80  ? 35  GLY B C   1 
ATOM   3459  O  O   . GLY B 1 56  ? -58.502 0.143   6.528   1.00 35.27  ? 35  GLY B O   1 
ATOM   3460  N  N   . LEU B 1 57  ? -57.096 1.070   8.018   1.00 26.40  ? 36  LEU B N   1 
ATOM   3461  C  CA  . LEU B 1 57  ? -58.105 1.077   9.069   1.00 26.94  ? 36  LEU B CA  1 
ATOM   3462  C  C   . LEU B 1 57  ? -59.062 2.251   8.885   1.00 30.57  ? 36  LEU B C   1 
ATOM   3463  O  O   . LEU B 1 57  ? -58.695 3.303   8.350   1.00 33.65  ? 36  LEU B O   1 
ATOM   3464  C  CB  . LEU B 1 57  ? -57.460 1.185   10.461  1.00 29.46  ? 36  LEU B CB  1 
ATOM   3465  C  CG  . LEU B 1 57  ? -56.586 -0.010  10.854  1.00 32.12  ? 36  LEU B CG  1 
ATOM   3466  C  CD1 . LEU B 1 57  ? -55.951 0.151   12.264  1.00 28.60  ? 36  LEU B CD1 1 
ATOM   3467  C  CD2 . LEU B 1 57  ? -57.458 -1.264  10.789  1.00 40.44  ? 36  LEU B CD2 1 
ATOM   3468  N  N   . GLU B 1 58  ? -60.276 2.081   9.393   1.00 30.42  ? 37  GLU B N   1 
ATOM   3469  C  CA  . GLU B 1 58  ? -61.201 3.202   9.360   1.00 31.91  ? 37  GLU B CA  1 
ATOM   3470  C  C   . GLU B 1 58  ? -60.848 4.204   10.455  1.00 28.12  ? 37  GLU B C   1 
ATOM   3471  O  O   . GLU B 1 58  ? -60.257 3.836   11.483  1.00 29.23  ? 37  GLU B O   1 
ATOM   3472  C  CB  . GLU B 1 58  ? -62.632 2.719   9.554   1.00 44.82  ? 37  GLU B CB  1 
ATOM   3473  C  CG  . GLU B 1 58  ? -63.185 1.954   8.359   1.00 64.94  ? 37  GLU B CG  1 
ATOM   3474  C  CD  . GLU B 1 58  ? -64.592 1.426   8.608   1.00 89.59  ? 37  GLU B CD  1 
ATOM   3475  O  OE1 . GLU B 1 58  ? -65.126 1.657   9.718   1.00 84.45  ? 37  GLU B OE1 1 
ATOM   3476  O  OE2 . GLU B 1 58  ? -65.160 0.781   7.696   1.00 91.91  ? 37  GLU B OE2 1 
ATOM   3477  N  N   . PRO B 1 59  ? -61.209 5.468   10.266  1.00 34.62  ? 38  PRO B N   1 
ATOM   3478  C  CA  . PRO B 1 59  ? -61.102 6.434   11.366  1.00 39.95  ? 38  PRO B CA  1 
ATOM   3479  C  C   . PRO B 1 59  ? -61.715 5.844   12.627  1.00 39.70  ? 38  PRO B C   1 
ATOM   3480  O  O   . PRO B 1 59  ? -62.703 5.110   12.557  1.00 38.47  ? 38  PRO B O   1 
ATOM   3481  C  CB  . PRO B 1 59  ? -61.906 7.639   10.862  1.00 34.23  ? 38  PRO B CB  1 
ATOM   3482  C  CG  . PRO B 1 59  ? -61.913 7.524   9.375   1.00 34.03  ? 38  PRO B CG  1 
ATOM   3483  C  CD  . PRO B 1 59  ? -61.730 6.061   9.025   1.00 35.27  ? 38  PRO B CD  1 
ATOM   3484  N  N   . GLU B 1 60  ? -61.092 6.126   13.777  1.00 26.06  ? 39  GLU B N   1 
ATOM   3485  C  CA  . GLU B 1 60  ? -61.551 5.717   15.117  1.00 32.09  ? 39  GLU B CA  1 
ATOM   3486  C  C   . GLU B 1 60  ? -61.383 4.230   15.430  1.00 30.76  ? 39  GLU B C   1 
ATOM   3487  O  O   . GLU B 1 60  ? -61.806 3.792   16.513  1.00 32.18  ? 39  GLU B O   1 
ATOM   3488  C  CB  . GLU B 1 60  ? -63.011 6.093   15.389  1.00 35.56  ? 39  GLU B CB  1 
ATOM   3489  C  CG  . GLU B 1 60  ? -63.358 7.540   15.073  1.00 47.03  ? 39  GLU B CG  1 
ATOM   3490  C  CD  . GLU B 1 60  ? -62.534 8.588   15.840  1.00 57.77  ? 39  GLU B CD  1 
ATOM   3491  O  OE1 . GLU B 1 60  ? -61.786 8.275   16.835  1.00 32.05  ? 39  GLU B OE1 1 
ATOM   3492  O  OE2 . GLU B 1 60  ? -62.675 9.756   15.421  1.00 46.76  ? 39  GLU B OE2 1 
ATOM   3493  N  N   . SER B 1 61  ? -60.760 3.452   14.539  1.00 29.93  ? 40  SER B N   1 
ATOM   3494  C  CA  . SER B 1 61  ? -60.545 2.026   14.779  1.00 32.06  ? 40  SER B CA  1 
ATOM   3495  C  C   . SER B 1 61  ? -59.746 1.797   16.053  1.00 28.15  ? 40  SER B C   1 
ATOM   3496  O  O   . SER B 1 61  ? -58.766 2.489   16.317  1.00 28.38  ? 40  SER B O   1 
ATOM   3497  C  CB  . SER B 1 61  ? -59.793 1.396   13.602  1.00 33.34  ? 40  SER B CB  1 
ATOM   3498  O  OG  . SER B 1 61  ? -59.519 0.031   13.880  1.00 31.11  ? 40  SER B OG  1 
ATOM   3499  N  N   . MET B 1 62  ? -60.156 0.809   16.834  1.00 28.00  ? 41  MET B N   1 
ATOM   3500  C  CA  . MET B 1 62  ? -59.364 0.364   17.974  1.00 27.59  ? 41  MET B CA  1 
ATOM   3501  C  C   . MET B 1 62  ? -58.467 -0.831  17.634  1.00 30.19  ? 41  MET B C   1 
ATOM   3502  O  O   . MET B 1 62  ? -57.923 -1.456  18.549  1.00 35.97  ? 41  MET B O   1 
ATOM   3503  C  CB  . MET B 1 62  ? -60.270 0.016   19.159  1.00 30.73  ? 41  MET B CB  1 
ATOM   3504  C  CG  . MET B 1 62  ? -61.357 1.071   19.393  1.00 39.30  ? 41  MET B CG  1 
ATOM   3505  S  SD  . MET B 1 62  ? -60.683 2.748   19.644  1.00 46.16  ? 41  MET B SD  1 
ATOM   3506  C  CE  . MET B 1 62  ? -59.966 2.529   21.278  1.00 33.33  ? 41  MET B CE  1 
ATOM   3507  N  N   A CYS B 1 63  ? -58.281 -1.141  16.344  0.32 31.07  ? 42  CYS B N   1 
ATOM   3508  N  N   B CYS B 1 63  ? -58.330 -1.167  16.352  0.68 31.07  ? 42  CYS B N   1 
ATOM   3509  C  CA  A CYS B 1 63  ? -57.460 -2.280  15.930  0.32 27.76  ? 42  CYS B CA  1 
ATOM   3510  C  CA  B CYS B 1 63  ? -57.426 -2.228  15.951  0.68 27.66  ? 42  CYS B CA  1 
ATOM   3511  C  C   A CYS B 1 63  ? -55.979 -1.899  15.917  0.32 30.19  ? 42  CYS B C   1 
ATOM   3512  C  C   B CYS B 1 63  ? -55.970 -1.805  16.123  0.68 30.05  ? 42  CYS B C   1 
ATOM   3513  O  O   A CYS B 1 63  ? -55.622 -0.843  15.385  0.32 27.58  ? 42  CYS B O   1 
ATOM   3514  O  O   B CYS B 1 63  ? -55.618 -0.640  15.923  0.68 28.99  ? 42  CYS B O   1 
ATOM   3515  C  CB  A CYS B 1 63  ? -57.890 -2.766  14.544  0.32 31.87  ? 42  CYS B CB  1 
ATOM   3516  C  CB  B CYS B 1 63  ? -57.658 -2.609  14.498  0.68 31.71  ? 42  CYS B CB  1 
ATOM   3517  S  SG  A CYS B 1 63  ? -57.191 -4.353  14.000  0.32 37.99  ? 42  CYS B SG  1 
ATOM   3518  S  SG  B CYS B 1 63  ? -59.275 -3.273  14.211  0.68 35.92  ? 42  CYS B SG  1 
ATOM   3519  N  N   . PRO B 1 64  ? -55.097 -2.739  16.465  1.00 28.49  ? 43  PRO B N   1 
ATOM   3520  C  CA  . PRO B 1 64  ? -53.666 -2.424  16.469  1.00 28.27  ? 43  PRO B CA  1 
ATOM   3521  C  C   . PRO B 1 64  ? -53.107 -2.357  15.053  1.00 28.62  ? 43  PRO B C   1 
ATOM   3522  O  O   . PRO B 1 64  ? -53.649 -2.946  14.115  1.00 32.84  ? 43  PRO B O   1 
ATOM   3523  C  CB  . PRO B 1 64  ? -53.047 -3.588  17.249  1.00 30.93  ? 43  PRO B CB  1 
ATOM   3524  C  CG  . PRO B 1 64  ? -54.037 -4.710  17.137  1.00 42.93  ? 43  PRO B CG  1 
ATOM   3525  C  CD  . PRO B 1 64  ? -55.402 -4.050  17.075  1.00 32.73  ? 43  PRO B CD  1 
ATOM   3526  N  N   . VAL B 1 65  ? -52.028 -1.600  14.889  1.00 25.02  ? 44  VAL B N   1 
ATOM   3527  C  CA  . VAL B 1 65  ? -51.311 -1.544  13.613  1.00 24.22  ? 44  VAL B CA  1 
ATOM   3528  C  C   . VAL B 1 65  ? -49.842 -1.832  13.891  1.00 28.92  ? 44  VAL B C   1 
ATOM   3529  O  O   . VAL B 1 65  ? -49.279 -1.315  14.863  1.00 26.25  ? 44  VAL B O   1 
ATOM   3530  C  CB  . VAL B 1 65  ? -51.519 -0.189  12.886  1.00 25.72  ? 44  VAL B CB  1 
ATOM   3531  C  CG1 . VAL B 1 65  ? -51.119 1.008   13.748  1.00 33.80  ? 44  VAL B CG1 1 
ATOM   3532  C  CG2 . VAL B 1 65  ? -50.746 -0.139  11.561  1.00 26.74  ? 44  VAL B CG2 1 
ATOM   3533  N  N   . THR B 1 66  ? -49.241 -2.701  13.081  1.00 31.25  ? 45  THR B N   1 
ATOM   3534  C  CA  . THR B 1 66  ? -47.859 -3.144  13.285  1.00 24.02  ? 45  THR B CA  1 
ATOM   3535  C  C   . THR B 1 66  ? -46.990 -2.649  12.146  1.00 27.16  ? 45  THR B C   1 
ATOM   3536  O  O   . THR B 1 66  ? -47.383 -2.718  10.977  1.00 28.71  ? 45  THR B O   1 
ATOM   3537  C  CB  . THR B 1 66  ? -47.787 -4.677  13.380  1.00 22.39  ? 45  THR B CB  1 
ATOM   3538  O  OG1 . THR B 1 66  ? -48.610 -5.101  14.470  1.00 28.92  ? 45  THR B OG1 1 
ATOM   3539  C  CG2 . THR B 1 66  ? -46.338 -5.160  13.592  1.00 34.50  ? 45  THR B CG2 1 
ATOM   3540  N  N   . THR B 1 67  ? -45.813 -2.140  12.490  1.00 25.85  ? 46  THR B N   1 
ATOM   3541  C  CA  . THR B 1 67  ? -44.835 -1.749  11.483  1.00 28.91  ? 46  THR B CA  1 
ATOM   3542  C  C   . THR B 1 67  ? -43.468 -2.073  12.050  1.00 26.78  ? 46  THR B C   1 
ATOM   3543  O  O   . THR B 1 67  ? -43.355 -2.772  13.064  1.00 32.20  ? 46  THR B O   1 
ATOM   3544  C  CB  . THR B 1 67  ? -44.983 -0.272  11.094  1.00 33.12  ? 46  THR B CB  1 
ATOM   3545  O  OG1 . THR B 1 67  ? -44.102 0.013   10.000  1.00 38.95  ? 46  THR B OG1 1 
ATOM   3546  C  CG2 . THR B 1 67  ? -44.678 0.644   12.276  1.00 37.61  ? 46  THR B CG2 1 
ATOM   3547  N  N   . LYS B 1 68  ? -42.426 -1.582  11.392  1.00 29.40  ? 47  LYS B N   1 
ATOM   3548  C  CA  . LYS B 1 68  ? -41.059 -1.778  11.846  1.00 29.79  ? 47  LYS B CA  1 
ATOM   3549  C  C   . LYS B 1 68  ? -40.488 -0.436  12.292  1.00 31.84  ? 47  LYS B C   1 
ATOM   3550  O  O   . LYS B 1 68  ? -40.615 0.565   11.584  1.00 30.84  ? 47  LYS B O   1 
ATOM   3551  C  CB  . LYS B 1 68  ? -40.191 -2.419  10.760  1.00 37.41  ? 47  LYS B CB  1 
ATOM   3552  C  CG  . LYS B 1 68  ? -40.162 -3.945  10.876  1.00 48.39  ? 47  LYS B CG  1 
ATOM   3553  C  CD  . LYS B 1 68  ? -39.295 -4.600  9.811   1.00 66.24  ? 47  LYS B CD  1 
ATOM   3554  C  CE  . LYS B 1 68  ? -38.865 -6.015  10.214  1.00 63.51  ? 47  LYS B CE  1 
ATOM   3555  N  NZ  . LYS B 1 68  ? -40.001 -6.939  10.564  1.00 53.43  ? 47  LYS B NZ  1 
ATOM   3556  N  N   . LEU B 1 69  ? -39.908 -0.411  13.490  1.00 27.56  ? 48  LEU B N   1 
ATOM   3557  C  CA  . LEU B 1 69  ? -39.232 0.780   13.989  1.00 28.78  ? 48  LEU B CA  1 
ATOM   3558  C  C   . LEU B 1 69  ? -37.931 0.346   14.628  1.00 29.27  ? 48  LEU B C   1 
ATOM   3559  O  O   . LEU B 1 69  ? -37.926 -0.602  15.423  1.00 31.31  ? 48  LEU B O   1 
ATOM   3560  C  CB  . LEU B 1 69  ? -40.084 1.538   15.022  1.00 28.46  ? 48  LEU B CB  1 
ATOM   3561  C  CG  . LEU B 1 69  ? -41.413 2.142   14.517  1.00 37.54  ? 48  LEU B CG  1 
ATOM   3562  C  CD1 . LEU B 1 69  ? -42.259 2.686   15.669  1.00 35.23  ? 48  LEU B CD1 1 
ATOM   3563  C  CD2 . LEU B 1 69  ? -41.222 3.246   13.454  1.00 40.60  ? 48  LEU B CD2 1 
ATOM   3564  N  N   . LEU B 1 70  ? -36.850 1.048   14.305  1.00 35.28  ? 49  LEU B N   1 
ATOM   3565  C  CA  . LEU B 1 70  ? -35.529 0.725   14.851  1.00 38.10  ? 49  LEU B CA  1 
ATOM   3566  C  C   . LEU B 1 70  ? -35.180 -0.737  14.601  1.00 33.27  ? 49  LEU B C   1 
ATOM   3567  O  O   . LEU B 1 70  ? -34.620 -1.422  15.463  1.00 37.55  ? 49  LEU B O   1 
ATOM   3568  C  CB  . LEU B 1 70  ? -35.461 1.047   16.342  1.00 36.51  ? 49  LEU B CB  1 
ATOM   3569  C  CG  . LEU B 1 70  ? -35.694 2.532   16.596  1.00 46.94  ? 49  LEU B CG  1 
ATOM   3570  C  CD1 . LEU B 1 70  ? -36.038 2.750   18.038  1.00 49.60  ? 49  LEU B CD1 1 
ATOM   3571  C  CD2 . LEU B 1 70  ? -34.449 3.296   16.215  1.00 40.87  ? 49  LEU B CD2 1 
ATOM   3572  N  N   . GLY B 1 71  ? -35.550 -1.227  13.422  1.00 35.57  ? 50  GLY B N   1 
ATOM   3573  C  CA  . GLY B 1 71  ? -35.215 -2.574  13.023  1.00 32.99  ? 50  GLY B CA  1 
ATOM   3574  C  C   . GLY B 1 71  ? -35.940 -3.701  13.726  1.00 39.58  ? 50  GLY B C   1 
ATOM   3575  O  O   . GLY B 1 71  ? -35.513 -4.853  13.592  1.00 33.21  ? 50  GLY B O   1 
ATOM   3576  N  N   . GLN B 1 72  ? -37.018 -3.422  14.465  1.00 29.99  ? 51  GLN B N   1 
ATOM   3577  C  CA  . GLN B 1 72  ? -37.822 -4.456  15.104  1.00 30.56  ? 51  GLN B CA  1 
ATOM   3578  C  C   . GLN B 1 72  ? -39.296 -4.117  14.931  1.00 28.74  ? 51  GLN B C   1 
ATOM   3579  O  O   . GLN B 1 72  ? -39.666 -2.965  14.679  1.00 30.40  ? 51  GLN B O   1 
ATOM   3580  C  CB  . GLN B 1 72  ? -37.522 -4.605  16.609  1.00 28.47  ? 51  GLN B CB  1 
ATOM   3581  C  CG  . GLN B 1 72  ? -36.232 -5.345  16.894  1.00 36.48  ? 51  GLN B CG  1 
ATOM   3582  C  CD  . GLN B 1 72  ? -35.912 -5.357  18.355  1.00 43.24  ? 51  GLN B CD  1 
ATOM   3583  O  OE1 . GLN B 1 72  ? -35.656 -4.305  18.954  1.00 39.73  ? 51  GLN B OE1 1 
ATOM   3584  N  NE2 . GLN B 1 72  ? -35.962 -6.547  18.961  1.00 38.99  ? 51  GLN B NE2 1 
ATOM   3585  N  N   . ASP B 1 73  ? -40.141 -5.122  15.119  1.00 28.88  ? 52  ASP B N   1 
ATOM   3586  C  CA  . ASP B 1 73  ? -41.571 -4.872  15.034  1.00 25.36  ? 52  ASP B CA  1 
ATOM   3587  C  C   . ASP B 1 73  ? -41.992 -3.914  16.139  1.00 31.84  ? 52  ASP B C   1 
ATOM   3588  O  O   . ASP B 1 73  ? -41.401 -3.897  17.224  1.00 24.27  ? 52  ASP B O   1 
ATOM   3589  C  CB  . ASP B 1 73  ? -42.357 -6.167  15.169  1.00 26.37  ? 52  ASP B CB  1 
ATOM   3590  C  CG  . ASP B 1 73  ? -42.471 -6.922  13.846  1.00 47.37  ? 52  ASP B CG  1 
ATOM   3591  O  OD1 . ASP B 1 73  ? -42.020 -6.391  12.810  1.00 39.52  ? 52  ASP B OD1 1 
ATOM   3592  O  OD2 . ASP B 1 73  ? -43.021 -8.037  13.849  1.00 45.27  ? 52  ASP B OD2 1 
ATOM   3593  N  N   . ALA B 1 74  ? -43.031 -3.129  15.849  1.00 25.34  ? 53  ALA B N   1 
ATOM   3594  C  CA  . ALA B 1 74  ? -43.653 -2.221  16.799  1.00 20.57  ? 53  ALA B CA  1 
ATOM   3595  C  C   . ALA B 1 74  ? -45.150 -2.233  16.537  1.00 24.11  ? 53  ALA B C   1 
ATOM   3596  O  O   . ALA B 1 74  ? -45.588 -2.036  15.393  1.00 26.49  ? 53  ALA B O   1 
ATOM   3597  C  CB  . ALA B 1 74  ? -43.082 -0.805  16.646  1.00 23.00  ? 53  ALA B CB  1 
ATOM   3598  N  N   . THR B 1 75  ? -45.942 -2.495  17.567  1.00 20.45  ? 54  THR B N   1 
ATOM   3599  C  CA  . THR B 1 75  ? -47.391 -2.521  17.407  1.00 22.13  ? 54  THR B CA  1 
ATOM   3600  C  C   . THR B 1 75  ? -47.987 -1.331  18.173  1.00 25.50  ? 54  THR B C   1 
ATOM   3601  O  O   . THR B 1 75  ? -47.789 -1.211  19.391  1.00 25.41  ? 54  THR B O   1 
ATOM   3602  C  CB  . THR B 1 75  ? -47.964 -3.849  17.906  1.00 27.44  ? 54  THR B CB  1 
ATOM   3603  O  OG1 . THR B 1 75  ? -47.505 -4.910  17.046  1.00 24.30  ? 54  THR B OG1 1 
ATOM   3604  C  CG2 . THR B 1 75  ? -49.487 -3.813  17.872  1.00 25.16  ? 54  THR B CG2 1 
ATOM   3605  N  N   . ILE B 1 76  ? -48.744 -0.477  17.477  1.00 21.42  ? 55  ILE B N   1 
ATOM   3606  C  CA  . ILE B 1 76  ? -49.288 0.745   18.082  1.00 20.38  ? 55  ILE B CA  1 
ATOM   3607  C  C   . ILE B 1 76  ? -50.721 0.463   18.508  1.00 23.41  ? 55  ILE B C   1 
ATOM   3608  O  O   . ILE B 1 76  ? -51.531 0.005   17.692  1.00 23.20  ? 55  ILE B O   1 
ATOM   3609  C  CB  . ILE B 1 76  ? -49.224 1.922   17.096  1.00 23.95  ? 55  ILE B CB  1 
ATOM   3610  C  CG1 . ILE B 1 76  ? -47.780 2.162   16.670  1.00 29.02  ? 55  ILE B CG1 1 
ATOM   3611  C  CG2 . ILE B 1 76  ? -49.896 3.213   17.706  1.00 22.08  ? 55  ILE B CG2 1 
ATOM   3612  C  CD1 . ILE B 1 76  ? -47.622 3.282   15.679  1.00 31.47  ? 55  ILE B CD1 1 
ATOM   3613  N  N   . VAL B 1 77  ? -51.043 0.755   19.777  1.00 20.45  ? 56  VAL B N   1 
ATOM   3614  C  CA  . VAL B 1 77  ? -52.355 0.472   20.351  1.00 21.38  ? 56  VAL B CA  1 
ATOM   3615  C  C   . VAL B 1 77  ? -52.874 1.759   20.980  1.00 24.29  ? 56  VAL B C   1 
ATOM   3616  O  O   . VAL B 1 77  ? -52.100 2.661   21.296  1.00 23.16  ? 56  VAL B O   1 
ATOM   3617  C  CB  . VAL B 1 77  ? -52.301 -0.663  21.387  1.00 25.81  ? 56  VAL B CB  1 
ATOM   3618  C  CG1 . VAL B 1 77  ? -51.687 -1.972  20.767  1.00 23.99  ? 56  VAL B CG1 1 
ATOM   3619  C  CG2 . VAL B 1 77  ? -51.522 -0.225  22.642  1.00 23.86  ? 56  VAL B CG2 1 
ATOM   3620  N  N   . ARG B 1 78  ? -54.199 1.858   21.139  1.00 25.55  ? 57  ARG B N   1 
ATOM   3621  C  CA  . ARG B 1 78  ? -54.767 3.035   21.808  1.00 27.12  ? 57  ARG B CA  1 
ATOM   3622  C  C   . ARG B 1 78  ? -56.067 2.654   22.486  1.00 26.83  ? 57  ARG B C   1 
ATOM   3623  O  O   . ARG B 1 78  ? -56.597 1.572   22.271  1.00 30.44  ? 57  ARG B O   1 
ATOM   3624  C  CB  . ARG B 1 78  ? -54.988 4.230   20.854  1.00 28.20  ? 57  ARG B CB  1 
ATOM   3625  C  CG  . ARG B 1 78  ? -55.751 3.960   19.586  1.00 35.59  ? 57  ARG B CG  1 
ATOM   3626  C  CD  . ARG B 1 78  ? -57.134 4.567   19.598  1.00 40.52  ? 57  ARG B CD  1 
ATOM   3627  N  NE  . ARG B 1 78  ? -57.730 4.500   18.269  1.00 29.17  ? 57  ARG B NE  1 
ATOM   3628  C  CZ  . ARG B 1 78  ? -57.918 5.546   17.476  1.00 27.58  ? 57  ARG B CZ  1 
ATOM   3629  N  NH1 . ARG B 1 78  ? -57.713 6.784   17.899  1.00 27.87  ? 57  ARG B NH1 1 
ATOM   3630  N  NH2 . ARG B 1 78  ? -58.371 5.351   16.240  1.00 26.89  ? 57  ARG B NH2 1 
ATOM   3631  N  N   . GLY B 1 79  ? -56.561 3.543   23.354  1.00 22.92  ? 58  GLY B N   1 
ATOM   3632  C  CA  . GLY B 1 79  ? -57.812 3.285   24.040  1.00 22.16  ? 58  GLY B CA  1 
ATOM   3633  C  C   . GLY B 1 79  ? -57.670 2.339   25.235  1.00 24.44  ? 58  GLY B C   1 
ATOM   3634  O  O   . GLY B 1 79  ? -56.595 1.867   25.587  1.00 23.94  ? 58  GLY B O   1 
ATOM   3635  N  N   . SER B 1 80  ? -58.812 2.026   25.852  1.00 24.02  ? 59  SER B N   1 
ATOM   3636  C  CA  . SER B 1 80  ? -58.773 1.386   27.169  1.00 25.77  ? 59  SER B CA  1 
ATOM   3637  C  C   . SER B 1 80  ? -58.118 0.004   27.133  1.00 27.56  ? 59  SER B C   1 
ATOM   3638  O  O   . SER B 1 80  ? -57.347 -0.351  28.038  1.00 24.95  ? 59  SER B O   1 
ATOM   3639  C  CB  . SER B 1 80  ? -60.189 1.305   27.734  1.00 35.53  ? 59  SER B CB  1 
ATOM   3640  O  OG  . SER B 1 80  ? -60.664 2.624   27.984  1.00 45.39  ? 59  SER B OG  1 
ATOM   3641  N  N   . ALA B 1 81  ? -58.429 -0.799  26.117  1.00 24.66  ? 60  ALA B N   1 
ATOM   3642  C  CA  . ALA B 1 81  ? -57.821 -2.122  26.002  1.00 26.21  ? 60  ALA B CA  1 
ATOM   3643  C  C   . ALA B 1 81  ? -56.315 -2.017  25.753  1.00 27.17  ? 60  ALA B C   1 
ATOM   3644  O  O   . ALA B 1 81  ? -55.540 -2.834  26.260  1.00 27.04  ? 60  ALA B O   1 
ATOM   3645  C  CB  . ALA B 1 81  ? -58.498 -2.922  24.878  1.00 30.97  ? 60  ALA B CB  1 
ATOM   3646  N  N   . GLY B 1 82  ? -55.889 -1.027  24.970  1.00 25.53  ? 61  GLY B N   1 
ATOM   3647  C  CA  . GLY B 1 82  ? -54.467 -0.827  24.746  1.00 24.83  ? 61  GLY B CA  1 
ATOM   3648  C  C   . GLY B 1 82  ? -53.740 -0.402  26.008  1.00 24.35  ? 61  GLY B C   1 
ATOM   3649  O  O   . GLY B 1 82  ? -52.606 -0.799  26.236  1.00 25.87  ? 61  GLY B O   1 
ATOM   3650  N  N   . ILE B 1 83  ? -54.402 0.400   26.850  1.00 21.82  ? 62  ILE B N   1 
ATOM   3651  C  CA  . ILE B 1 83  ? -53.850 0.773   28.145  1.00 23.24  ? 62  ILE B CA  1 
ATOM   3652  C  C   . ILE B 1 83  ? -53.646 -0.470  29.001  1.00 20.60  ? 62  ILE B C   1 
ATOM   3653  O  O   . ILE B 1 83  ? -52.607 -0.641  29.637  1.00 26.74  ? 62  ILE B O   1 
ATOM   3654  C  CB  . ILE B 1 83  ? -54.788 1.786   28.841  1.00 23.23  ? 62  ILE B CB  1 
ATOM   3655  C  CG1 . ILE B 1 83  ? -54.722 3.149   28.153  1.00 20.77  ? 62  ILE B CG1 1 
ATOM   3656  C  CG2 . ILE B 1 83  ? -54.455 1.883   30.331  1.00 24.28  ? 62  ILE B CG2 1 
ATOM   3657  C  CD1 . ILE B 1 83  ? -55.944 4.122   28.498  1.00 20.85  ? 62  ILE B CD1 1 
ATOM   3658  N  N   . ASP B 1 84  ? -54.655 -1.340  29.060  1.00 22.94  ? 63  ASP B N   1 
ATOM   3659  C  CA  . ASP B 1 84  ? -54.519 -2.552  29.866  1.00 26.22  ? 63  ASP B CA  1 
ATOM   3660  C  C   . ASP B 1 84  ? -53.324 -3.398  29.425  1.00 25.01  ? 63  ASP B C   1 
ATOM   3661  O  O   . ASP B 1 84  ? -52.618 -3.980  30.266  1.00 28.88  ? 63  ASP B O   1 
ATOM   3662  C  CB  . ASP B 1 84  ? -55.790 -3.397  29.772  1.00 25.77  ? 63  ASP B CB  1 
ATOM   3663  C  CG  . ASP B 1 84  ? -56.977 -2.742  30.438  1.00 31.89  ? 63  ASP B CG  1 
ATOM   3664  O  OD1 . ASP B 1 84  ? -56.785 -1.793  31.242  1.00 30.38  ? 63  ASP B OD1 1 
ATOM   3665  O  OD2 . ASP B 1 84  ? -58.098 -3.196  30.157  1.00 33.66  ? 63  ASP B OD2 1 
ATOM   3666  N  N   . LEU B 1 85  ? -53.145 -3.550  28.115  1.00 23.26  ? 64  LEU B N   1 
ATOM   3667  C  CA  . LEU B 1 85  ? -51.998 -4.300  27.591  1.00 21.16  ? 64  LEU B CA  1 
ATOM   3668  C  C   . LEU B 1 85  ? -50.686 -3.633  27.970  1.00 24.81  ? 64  LEU B C   1 
ATOM   3669  O  O   . LEU B 1 85  ? -49.749 -4.288  28.442  1.00 23.18  ? 64  LEU B O   1 
ATOM   3670  C  CB  . LEU B 1 85  ? -52.101 -4.415  26.072  1.00 20.47  ? 64  LEU B CB  1 
ATOM   3671  C  CG  . LEU B 1 85  ? -50.824 -5.009  25.444  1.00 24.51  ? 64  LEU B CG  1 
ATOM   3672  C  CD1 . LEU B 1 85  ? -50.701 -6.447  25.955  1.00 27.97  ? 64  LEU B CD1 1 
ATOM   3673  C  CD2 . LEU B 1 85  ? -50.846 -4.941  23.898  1.00 29.11  ? 64  LEU B CD2 1 
ATOM   3674  N  N   . PHE B 1 86  ? -50.603 -2.318  27.753  1.00 21.58  ? 65  PHE B N   1 
ATOM   3675  C  CA  . PHE B 1 86  ? -49.352 -1.594  27.932  1.00 21.73  ? 65  PHE B CA  1 
ATOM   3676  C  C   . PHE B 1 86  ? -48.885 -1.652  29.376  1.00 25.06  ? 65  PHE B C   1 
ATOM   3677  O  O   . PHE B 1 86  ? -47.681 -1.728  29.636  1.00 25.07  ? 65  PHE B O   1 
ATOM   3678  C  CB  . PHE B 1 86  ? -49.560 -0.142  27.479  1.00 22.39  ? 65  PHE B CB  1 
ATOM   3679  C  CG  . PHE B 1 86  ? -48.298 0.651   27.377  1.00 22.34  ? 65  PHE B CG  1 
ATOM   3680  C  CD1 . PHE B 1 86  ? -47.392 0.413   26.340  1.00 20.20  ? 65  PHE B CD1 1 
ATOM   3681  C  CD2 . PHE B 1 86  ? -48.025 1.658   28.311  1.00 24.47  ? 65  PHE B CD2 1 
ATOM   3682  C  CE1 . PHE B 1 86  ? -46.230 1.161   26.239  1.00 22.18  ? 65  PHE B CE1 1 
ATOM   3683  C  CE2 . PHE B 1 86  ? -46.846 2.432   28.201  1.00 22.23  ? 65  PHE B CE2 1 
ATOM   3684  C  CZ  . PHE B 1 86  ? -45.939 2.167   27.173  1.00 19.62  ? 65  PHE B CZ  1 
ATOM   3685  N  N   . TYR B 1 87  ? -49.824 -1.616  30.332  1.00 22.56  ? 66  TYR B N   1 
ATOM   3686  C  CA  . TYR B 1 87  ? -49.488 -1.605  31.747  1.00 24.77  ? 66  TYR B CA  1 
ATOM   3687  C  C   . TYR B 1 87  ? -49.537 -2.999  32.385  1.00 24.17  ? 66  TYR B C   1 
ATOM   3688  O  O   . TYR B 1 87  ? -49.490 -3.109  33.612  1.00 25.57  ? 66  TYR B O   1 
ATOM   3689  C  CB  . TYR B 1 87  ? -50.384 -0.608  32.488  1.00 24.61  ? 66  TYR B CB  1 
ATOM   3690  C  CG  . TYR B 1 87  ? -49.986 0.801   32.110  1.00 26.25  ? 66  TYR B CG  1 
ATOM   3691  C  CD1 . TYR B 1 87  ? -48.847 1.385   32.669  1.00 21.64  ? 66  TYR B CD1 1 
ATOM   3692  C  CD2 . TYR B 1 87  ? -50.697 1.514   31.140  1.00 22.74  ? 66  TYR B CD2 1 
ATOM   3693  C  CE1 . TYR B 1 87  ? -48.443 2.651   32.316  1.00 21.56  ? 66  TYR B CE1 1 
ATOM   3694  C  CE2 . TYR B 1 87  ? -50.301 2.801   30.776  1.00 21.43  ? 66  TYR B CE2 1 
ATOM   3695  C  CZ  . TYR B 1 87  ? -49.168 3.351   31.367  1.00 19.61  ? 66  TYR B CZ  1 
ATOM   3696  O  OH  . TYR B 1 87  ? -48.759 4.605   30.999  1.00 22.31  ? 66  TYR B OH  1 
ATOM   3697  N  N   . ASP B 1 88  ? -49.537 -4.059  31.574  1.00 24.85  ? 67  ASP B N   1 
ATOM   3698  C  CA  . ASP B 1 88  ? -49.541 -5.436  32.077  1.00 24.25  ? 67  ASP B CA  1 
ATOM   3699  C  C   . ASP B 1 88  ? -48.087 -5.870  32.262  1.00 23.31  ? 67  ASP B C   1 
ATOM   3700  O  O   . ASP B 1 88  ? -47.426 -6.280  31.309  1.00 26.25  ? 67  ASP B O   1 
ATOM   3701  C  CB  . ASP B 1 88  ? -50.282 -6.353  31.104  1.00 22.31  ? 67  ASP B CB  1 
ATOM   3702  C  CG  . ASP B 1 88  ? -50.406 -7.795  31.636  1.00 30.33  ? 67  ASP B CG  1 
ATOM   3703  O  OD1 . ASP B 1 88  ? -49.745 -8.126  32.626  1.00 29.79  ? 67  ASP B OD1 1 
ATOM   3704  O  OD2 . ASP B 1 88  ? -51.186 -8.582  31.071  1.00 29.33  ? 67  ASP B OD2 1 
ATOM   3705  N  N   . GLU B 1 89  ? -47.567 -5.760  33.485  1.00 23.48  ? 68  GLU B N   1 
ATOM   3706  C  CA  . GLU B 1 89  ? -46.146 -6.081  33.693  1.00 24.13  ? 68  GLU B CA  1 
ATOM   3707  C  C   . GLU B 1 89  ? -45.848 -7.585  33.641  1.00 28.98  ? 68  GLU B C   1 
ATOM   3708  O  O   . GLU B 1 89  ? -44.662 -7.969  33.705  1.00 27.59  ? 68  GLU B O   1 
ATOM   3709  C  CB  . GLU B 1 89  ? -45.672 -5.484  35.022  1.00 27.56  ? 68  GLU B CB  1 
ATOM   3710  C  CG  . GLU B 1 89  ? -45.831 -3.955  35.008  1.00 29.75  ? 68  GLU B CG  1 
ATOM   3711  C  CD  . GLU B 1 89  ? -45.091 -3.261  36.153  1.00 38.13  ? 68  GLU B CD  1 
ATOM   3712  O  OE1 . GLU B 1 89  ? -44.664 -3.964  37.090  1.00 38.88  ? 68  GLU B OE1 1 
ATOM   3713  O  OE2 . GLU B 1 89  ? -44.924 -2.014  36.106  1.00 33.23  ? 68  GLU B OE2 1 
ATOM   3714  N  N   . ASP B 1 90  ? -46.870 -8.425  33.472  1.00 27.93  ? 69  ASP B N   1 
ATOM   3715  C  CA  . ASP B 1 90  ? -46.641 -9.832  33.141  1.00 28.25  ? 69  ASP B CA  1 
ATOM   3716  C  C   . ASP B 1 90  ? -46.137 -10.031 31.716  1.00 33.80  ? 69  ASP B C   1 
ATOM   3717  O  O   . ASP B 1 90  ? -45.506 -11.052 31.450  1.00 32.92  ? 69  ASP B O   1 
ATOM   3718  C  CB  . ASP B 1 90  ? -47.922 -10.635 33.318  1.00 31.02  ? 69  ASP B CB  1 
ATOM   3719  C  CG  . ASP B 1 90  ? -48.338 -10.734 34.754  1.00 51.78  ? 69  ASP B CG  1 
ATOM   3720  O  OD1 . ASP B 1 90  ? -47.454 -10.572 35.627  1.00 53.40  ? 69  ASP B OD1 1 
ATOM   3721  O  OD2 . ASP B 1 90  ? -49.540 -10.972 35.010  1.00 73.52  ? 69  ASP B OD2 1 
ATOM   3722  N  N   . VAL B 1 91  ? -46.386 -9.093  30.801  1.00 26.81  ? 70  VAL B N   1 
ATOM   3723  C  CA  . VAL B 1 91  ? -45.962 -9.271  29.409  1.00 27.09  ? 70  VAL B CA  1 
ATOM   3724  C  C   . VAL B 1 91  ? -45.166 -8.084  28.869  1.00 26.66  ? 70  VAL B C   1 
ATOM   3725  O  O   . VAL B 1 91  ? -44.640 -8.146  27.759  1.00 25.78  ? 70  VAL B O   1 
ATOM   3726  C  CB  . VAL B 1 91  ? -47.172 -9.542  28.480  1.00 28.78  ? 70  VAL B CB  1 
ATOM   3727  C  CG1 . VAL B 1 91  ? -47.738 -10.932 28.712  1.00 32.30  ? 70  VAL B CG1 1 
ATOM   3728  C  CG2 . VAL B 1 91  ? -48.266 -8.491  28.687  1.00 28.32  ? 70  VAL B CG2 1 
ATOM   3729  N  N   . MET B 1 92  ? -45.102 -6.980  29.605  1.00 22.39  ? 71  MET B N   1 
ATOM   3730  C  CA  . MET B 1 92  ? -44.395 -5.800  29.142  1.00 20.57  ? 71  MET B CA  1 
ATOM   3731  C  C   . MET B 1 92  ? -43.270 -5.425  30.098  1.00 23.47  ? 71  MET B C   1 
ATOM   3732  O  O   . MET B 1 92  ? -43.436 -5.490  31.319  1.00 24.32  ? 71  MET B O   1 
ATOM   3733  C  CB  . MET B 1 92  ? -45.342 -4.586  29.021  1.00 21.12  ? 71  MET B CB  1 
ATOM   3734  C  CG  . MET B 1 92  ? -46.489 -4.777  27.983  1.00 24.91  ? 71  MET B CG  1 
ATOM   3735  S  SD  . MET B 1 92  ? -45.884 -4.788  26.276  1.00 29.83  ? 71  MET B SD  1 
ATOM   3736  C  CE  . MET B 1 92  ? -46.468 -6.414  25.785  1.00 30.91  ? 71  MET B CE  1 
ATOM   3737  N  N   . GLN B 1 93  ? -42.146 -4.977  29.537  1.00 20.41  ? 72  GLN B N   1 
ATOM   3738  C  CA  . GLN B 1 93  ? -41.080 -4.391  30.333  1.00 25.24  ? 72  GLN B CA  1 
ATOM   3739  C  C   . GLN B 1 93  ? -40.630 -3.091  29.678  1.00 26.62  ? 72  GLN B C   1 
ATOM   3740  O  O   . GLN B 1 93  ? -40.948 -2.813  28.521  1.00 24.84  ? 72  GLN B O   1 
ATOM   3741  C  CB  . GLN B 1 93  ? -39.902 -5.373  30.486  1.00 27.00  ? 72  GLN B CB  1 
ATOM   3742  C  CG  . GLN B 1 93  ? -39.114 -5.651  29.223  1.00 22.11  ? 72  GLN B CG  1 
ATOM   3743  C  CD  . GLN B 1 93  ? -38.088 -6.786  29.495  1.00 39.51  ? 72  GLN B CD  1 
ATOM   3744  O  OE1 . GLN B 1 93  ? -37.720 -7.059  30.656  1.00 44.19  ? 72  GLN B OE1 1 
ATOM   3745  N  NE2 . GLN B 1 93  ? -37.693 -7.473  28.461  1.00 36.04  ? 72  GLN B NE2 1 
ATOM   3746  N  N   . ARG B 1 94  ? -39.912 -2.259  30.430  1.00 20.10  ? 73  ARG B N   1 
ATOM   3747  C  CA  . ARG B 1 94  ? -39.481 -0.992  29.862  1.00 21.50  ? 73  ARG B CA  1 
ATOM   3748  C  C   . ARG B 1 94  ? -38.006 -0.928  29.496  1.00 21.34  ? 73  ARG B C   1 
ATOM   3749  O  O   . ARG B 1 94  ? -37.611 -0.028  28.744  1.00 23.52  ? 73  ARG B O   1 
ATOM   3750  C  CB  . ARG B 1 94  ? -39.816 0.160   30.828  1.00 21.03  ? 73  ARG B CB  1 
ATOM   3751  C  CG  . ARG B 1 94  ? -41.298 0.160   31.206  1.00 20.27  ? 73  ARG B CG  1 
ATOM   3752  C  CD  . ARG B 1 94  ? -42.218 0.256   29.967  1.00 19.22  ? 73  ARG B CD  1 
ATOM   3753  N  NE  . ARG B 1 94  ? -43.598 0.502   30.398  1.00 21.17  ? 73  ARG B NE  1 
ATOM   3754  C  CZ  . ARG B 1 94  ? -44.068 1.721   30.650  1.00 22.88  ? 73  ARG B CZ  1 
ATOM   3755  N  NH1 . ARG B 1 94  ? -43.307 2.792   30.487  1.00 20.67  ? 73  ARG B NH1 1 
ATOM   3756  N  NH2 . ARG B 1 94  ? -45.327 1.867   31.081  1.00 21.57  ? 73  ARG B NH2 1 
ATOM   3757  N  N   . GLU B 1 95  ? -37.174 -1.822  30.030  1.00 24.82  ? 74  GLU B N   1 
ATOM   3758  C  CA  . GLU B 1 95  ? -35.755 -1.721  29.740  1.00 24.37  ? 74  GLU B CA  1 
ATOM   3759  C  C   . GLU B 1 95  ? -35.513 -1.869  28.242  1.00 31.12  ? 74  GLU B C   1 
ATOM   3760  O  O   . GLU B 1 95  ? -36.001 -2.807  27.598  1.00 25.77  ? 74  GLU B O   1 
ATOM   3761  C  CB  . GLU B 1 95  ? -34.968 -2.777  30.530  1.00 28.83  ? 74  GLU B CB  1 
ATOM   3762  C  CG  . GLU B 1 95  ? -33.464 -2.645  30.309  1.00 33.25  ? 74  GLU B CG  1 
ATOM   3763  C  CD  . GLU B 1 95  ? -32.655 -3.694  31.092  1.00 48.23  ? 74  GLU B CD  1 
ATOM   3764  O  OE1 . GLU B 1 95  ? -33.179 -4.254  32.081  1.00 58.44  ? 74  GLU B OE1 1 
ATOM   3765  O  OE2 . GLU B 1 95  ? -31.497 -3.966  30.709  1.00 54.95  ? 74  GLU B OE2 1 
ATOM   3766  N  N   . GLY B 1 96  ? -34.801 -0.902  27.682  1.00 26.39  ? 75  GLY B N   1 
ATOM   3767  C  CA  . GLY B 1 96  ? -34.516 -0.865  26.263  1.00 29.77  ? 75  GLY B CA  1 
ATOM   3768  C  C   . GLY B 1 96  ? -35.657 -0.423  25.374  1.00 31.98  ? 75  GLY B C   1 
ATOM   3769  O  O   . GLY B 1 96  ? -35.454 -0.295  24.154  1.00 26.54  ? 75  GLY B O   1 
ATOM   3770  N  N   . ALA B 1 97  ? -36.846 -0.139  25.930  1.00 21.16  ? 76  ALA B N   1 
ATOM   3771  C  CA  . ALA B 1 97  ? -37.973 0.206   25.059  1.00 23.40  ? 76  ALA B CA  1 
ATOM   3772  C  C   . ALA B 1 97  ? -37.804 1.588   24.434  1.00 23.60  ? 76  ALA B C   1 
ATOM   3773  O  O   . ALA B 1 97  ? -38.053 1.776   23.229  1.00 23.40  ? 76  ALA B O   1 
ATOM   3774  C  CB  . ALA B 1 97  ? -39.277 0.118   25.855  1.00 24.71  ? 76  ALA B CB  1 
ATOM   3775  N  N   . MET B 1 98  ? -37.376 2.567   25.224  1.00 24.71  ? 77  MET B N   1 
ATOM   3776  C  CA  . MET B 1 98  ? -37.146 3.906   24.693  1.00 26.55  ? 77  MET B CA  1 
ATOM   3777  C  C   . MET B 1 98  ? -35.790 3.949   23.991  1.00 29.61  ? 77  MET B C   1 
ATOM   3778  O  O   . MET B 1 98  ? -34.781 3.542   24.588  1.00 26.25  ? 77  MET B O   1 
ATOM   3779  C  CB  . MET B 1 98  ? -37.204 4.914   25.852  1.00 27.60  ? 77  MET B CB  1 
ATOM   3780  C  CG  . MET B 1 98  ? -37.016 6.369   25.470  1.00 25.57  ? 77  MET B CG  1 
ATOM   3781  S  SD  . MET B 1 98  ? -38.394 7.036   24.516  1.00 28.92  ? 77  MET B SD  1 
ATOM   3782  C  CE  . MET B 1 98  ? -39.661 7.203   25.795  1.00 25.58  ? 77  MET B CE  1 
ATOM   3783  N  N   . PRO B 1 99  ? -35.719 4.401   22.738  1.00 29.40  ? 78  PRO B N   1 
ATOM   3784  C  CA  . PRO B 1 99  ? -34.405 4.565   22.081  1.00 29.23  ? 78  PRO B CA  1 
ATOM   3785  C  C   . PRO B 1 99  ? -33.501 5.431   22.932  1.00 27.74  ? 78  PRO B C   1 
ATOM   3786  O  O   . PRO B 1 99  ? -33.928 6.484   23.409  1.00 26.29  ? 78  PRO B O   1 
ATOM   3787  C  CB  . PRO B 1 99  ? -34.737 5.274   20.758  1.00 31.23  ? 78  PRO B CB  1 
ATOM   3788  C  CG  . PRO B 1 99  ? -36.192 5.148   20.583  1.00 40.32  ? 78  PRO B CG  1 
ATOM   3789  C  CD  . PRO B 1 99  ? -36.815 4.970   21.932  1.00 29.84  ? 78  PRO B CD  1 
ATOM   3790  N  N   . PRO B 1 100 ? -32.255 5.025   23.141  1.00 27.95  ? 79  PRO B N   1 
ATOM   3791  C  CA  . PRO B 1 100 ? -31.362 5.812   24.003  1.00 27.09  ? 79  PRO B CA  1 
ATOM   3792  C  C   . PRO B 1 100 ? -31.161 7.225   23.529  1.00 25.96  ? 79  PRO B C   1 
ATOM   3793  O  O   . PRO B 1 100 ? -30.933 8.112   24.356  1.00 31.86  ? 79  PRO B O   1 
ATOM   3794  C  CB  . PRO B 1 100 ? -30.045 5.024   23.955  1.00 40.80  ? 79  PRO B CB  1 
ATOM   3795  C  CG  . PRO B 1 100 ? -30.451 3.631   23.640  1.00 39.11  ? 79  PRO B CG  1 
ATOM   3796  C  CD  . PRO B 1 100 ? -31.678 3.721   22.769  1.00 32.64  ? 79  PRO B CD  1 
ATOM   3797  N  N   . VAL B 1 101 ? -31.260 7.476   22.226  1.00 24.59  ? 80  VAL B N   1 
ATOM   3798  C  CA  . VAL B 1 101 ? -31.025 8.833   21.757  1.00 27.83  ? 80  VAL B CA  1 
ATOM   3799  C  C   . VAL B 1 101 ? -32.055 9.791   22.345  1.00 25.24  ? 80  VAL B C   1 
ATOM   3800  O  O   . VAL B 1 101 ? -31.773 10.973  22.542  1.00 27.32  ? 80  VAL B O   1 
ATOM   3801  C  CB  . VAL B 1 101 ? -31.014 8.888   20.221  1.00 31.08  ? 80  VAL B CB  1 
ATOM   3802  C  CG1 . VAL B 1 101 ? -32.379 8.542   19.653  1.00 31.52  ? 80  VAL B CG1 1 
ATOM   3803  C  CG2 . VAL B 1 101 ? -30.562 10.276  19.772  1.00 35.56  ? 80  VAL B CG2 1 
ATOM   3804  N  N   . ILE B 1 102 ? -33.244 9.286   22.679  1.00 25.05  ? 81  ILE B N   1 
ATOM   3805  C  CA  . ILE B 1 102 ? -34.241 10.085  23.389  1.00 20.79  ? 81  ILE B CA  1 
ATOM   3806  C  C   . ILE B 1 102 ? -34.045 9.939   24.892  1.00 26.48  ? 81  ILE B C   1 
ATOM   3807  O  O   . ILE B 1 102 ? -33.860 10.932  25.611  1.00 27.36  ? 81  ILE B O   1 
ATOM   3808  C  CB  . ILE B 1 102 ? -35.666 9.651   22.998  1.00 22.92  ? 81  ILE B CB  1 
ATOM   3809  C  CG1 . ILE B 1 102 ? -35.905 9.910   21.521  1.00 30.45  ? 81  ILE B CG1 1 
ATOM   3810  C  CG2 . ILE B 1 102 ? -36.698 10.387  23.895  1.00 26.20  ? 81  ILE B CG2 1 
ATOM   3811  C  CD1 . ILE B 1 102 ? -37.178 9.295   20.982  1.00 39.64  ? 81  ILE B CD1 1 
ATOM   3812  N  N   . GLY B 1 103 ? -34.074 8.689   25.363  1.00 26.04  ? 82  GLY B N   1 
ATOM   3813  C  CA  . GLY B 1 103 ? -34.146 8.443   26.798  1.00 25.72  ? 82  GLY B CA  1 
ATOM   3814  C  C   . GLY B 1 103 ? -32.904 8.900   27.537  1.00 27.79  ? 82  GLY B C   1 
ATOM   3815  O  O   . GLY B 1 103 ? -32.994 9.443   28.639  1.00 24.16  ? 82  GLY B O   1 
ATOM   3816  N  N   . ASP B 1 104 ? -31.723 8.678   26.955  1.00 25.13  ? 83  ASP B N   1 
ATOM   3817  C  CA  . ASP B 1 104 ? -30.518 9.066   27.677  1.00 24.58  ? 83  ASP B CA  1 
ATOM   3818  C  C   . ASP B 1 104 ? -30.417 10.583  27.824  1.00 28.42  ? 83  ASP B C   1 
ATOM   3819  O  O   . ASP B 1 104 ? -29.811 11.070  28.791  1.00 28.25  ? 83  ASP B O   1 
ATOM   3820  C  CB  . ASP B 1 104 ? -29.261 8.536   26.977  1.00 28.46  ? 83  ASP B CB  1 
ATOM   3821  C  CG  . ASP B 1 104 ? -29.034 7.043   27.202  1.00 36.99  ? 83  ASP B CG  1 
ATOM   3822  O  OD1 . ASP B 1 104 ? -29.785 6.410   27.981  1.00 34.86  ? 83  ASP B OD1 1 
ATOM   3823  O  OD2 . ASP B 1 104 ? -28.086 6.507   26.581  1.00 36.52  ? 83  ASP B OD2 1 
ATOM   3824  N  N   . ALA B 1 105 ? -30.974 11.347  26.879  1.00 23.36  ? 84  ALA B N   1 
ATOM   3825  C  CA  . ALA B 1 105 ? -30.982 12.799  27.054  1.00 25.30  ? 84  ALA B CA  1 
ATOM   3826  C  C   . ALA B 1 105 ? -32.117 13.225  27.973  1.00 27.56  ? 84  ALA B C   1 
ATOM   3827  O  O   . ALA B 1 105 ? -31.938 14.085  28.851  1.00 27.61  ? 84  ALA B O   1 
ATOM   3828  C  CB  . ALA B 1 105 ? -31.125 13.502  25.698  1.00 27.73  ? 84  ALA B CB  1 
ATOM   3829  N  N   . LEU B 1 106 ? -33.307 12.675  27.739  1.00 22.76  ? 85  LEU B N   1 
ATOM   3830  C  CA  . LEU B 1 106 ? -34.502 13.182  28.421  1.00 22.01  ? 85  LEU B CA  1 
ATOM   3831  C  C   . LEU B 1 106 ? -34.520 12.803  29.899  1.00 26.72  ? 85  LEU B C   1 
ATOM   3832  O  O   . LEU B 1 106 ? -34.736 13.668  30.761  1.00 26.12  ? 85  LEU B O   1 
ATOM   3833  C  CB  . LEU B 1 106 ? -35.774 12.689  27.711  1.00 22.10  ? 85  LEU B CB  1 
ATOM   3834  C  CG  . LEU B 1 106 ? -37.062 13.209  28.381  1.00 25.60  ? 85  LEU B CG  1 
ATOM   3835  C  CD1 . LEU B 1 106 ? -37.074 14.730  28.462  1.00 26.89  ? 85  LEU B CD1 1 
ATOM   3836  C  CD2 . LEU B 1 106 ? -38.296 12.701  27.603  1.00 27.33  ? 85  LEU B CD2 1 
ATOM   3837  N  N   . VAL B 1 107 ? -34.322 11.524  30.232  1.00 24.85  ? 86  VAL B N   1 
ATOM   3838  C  CA  . VAL B 1 107 ? -34.404 11.110  31.637  1.00 27.01  ? 86  VAL B CA  1 
ATOM   3839  C  C   . VAL B 1 107 ? -33.059 10.681  32.224  1.00 25.64  ? 86  VAL B C   1 
ATOM   3840  O  O   . VAL B 1 107 ? -32.946 10.579  33.456  1.00 26.18  ? 86  VAL B O   1 
ATOM   3841  C  CB  . VAL B 1 107 ? -35.464 10.008  31.854  1.00 22.40  ? 86  VAL B CB  1 
ATOM   3842  C  CG1 . VAL B 1 107 ? -36.833 10.469  31.305  1.00 25.48  ? 86  VAL B CG1 1 
ATOM   3843  C  CG2 . VAL B 1 107 ? -35.049 8.658   31.209  1.00 23.57  ? 86  VAL B CG2 1 
ATOM   3844  N  N   . GLY B 1 108 ? -32.041 10.469  31.413  1.00 25.31  ? 87  GLY B N   1 
ATOM   3845  C  CA  . GLY B 1 108 ? -30.741 10.055  31.927  1.00 24.34  ? 87  GLY B CA  1 
ATOM   3846  C  C   . GLY B 1 108 ? -30.583 8.546   32.014  1.00 30.69  ? 87  GLY B C   1 
ATOM   3847  O  O   . GLY B 1 108 ? -31.545 7.783   32.003  1.00 25.94  ? 87  GLY B O   1 
ATOM   3848  N  N   . LYS B 1 109 ? -29.325 8.111   32.147  1.00 28.70  ? 88  LYS B N   1 
ATOM   3849  C  CA  . LYS B 1 109 ? -29.022 6.687   32.251  1.00 28.45  ? 88  LYS B CA  1 
ATOM   3850  C  C   . LYS B 1 109 ? -29.360 6.144   33.634  1.00 33.92  ? 88  LYS B C   1 
ATOM   3851  O  O   . LYS B 1 109 ? -29.158 6.819   34.652  1.00 28.68  ? 88  LYS B O   1 
ATOM   3852  C  CB  . LYS B 1 109 ? -27.538 6.445   31.959  1.00 31.23  ? 88  LYS B CB  1 
ATOM   3853  C  CG  . LYS B 1 109 ? -27.153 6.762   30.529  1.00 30.20  ? 88  LYS B CG  1 
ATOM   3854  C  CD  . LYS B 1 109 ? -25.631 6.649   30.316  1.00 35.90  ? 88  LYS B CD  1 
ATOM   3855  C  CE  . LYS B 1 109 ? -25.248 7.078   28.910  1.00 48.05  ? 88  LYS B CE  1 
ATOM   3856  N  NZ  . LYS B 1 109 ? -23.765 7.104   28.702  1.00 54.62  ? 88  LYS B NZ  1 
ATOM   3857  N  N   . GLY B 1 110 ? -29.884 4.919   33.668  1.00 30.38  ? 89  GLY B N   1 
ATOM   3858  C  CA  . GLY B 1 110 ? -30.213 4.299   34.945  1.00 32.62  ? 89  GLY B CA  1 
ATOM   3859  C  C   . GLY B 1 110 ? -31.459 4.839   35.620  1.00 39.80  ? 89  GLY B C   1 
ATOM   3860  O  O   . GLY B 1 110 ? -31.723 4.493   36.778  1.00 32.56  ? 89  GLY B O   1 
ATOM   3861  N  N   . ALA B 1 111 ? -32.245 5.660   34.924  1.00 30.33  ? 90  ALA B N   1 
ATOM   3862  C  CA  . ALA B 1 111 ? -33.419 6.276   35.539  1.00 29.62  ? 90  ALA B CA  1 
ATOM   3863  C  C   . ALA B 1 111 ? -34.498 5.238   35.832  1.00 26.11  ? 90  ALA B C   1 
ATOM   3864  O  O   . ALA B 1 111 ? -34.550 4.177   35.215  1.00 25.78  ? 90  ALA B O   1 
ATOM   3865  C  CB  . ALA B 1 111 ? -34.004 7.359   34.632  1.00 27.82  ? 90  ALA B CB  1 
ATOM   3866  N  N   . VAL B 1 112 ? -35.384 5.575   36.783  1.00 22.07  ? 91  VAL B N   1 
ATOM   3867  C  CA  . VAL B 1 112 ? -36.521 4.717   37.128  1.00 24.44  ? 91  VAL B CA  1 
ATOM   3868  C  C   . VAL B 1 112 ? -37.299 4.264   35.888  1.00 23.75  ? 91  VAL B C   1 
ATOM   3869  O  O   . VAL B 1 112 ? -37.879 3.167   35.877  1.00 24.49  ? 91  VAL B O   1 
ATOM   3870  C  CB  . VAL B 1 112 ? -37.444 5.462   38.124  1.00 25.15  ? 91  VAL B CB  1 
ATOM   3871  C  CG1 . VAL B 1 112 ? -38.022 6.769   37.476  1.00 26.59  ? 91  VAL B CG1 1 
ATOM   3872  C  CG2 . VAL B 1 112 ? -38.580 4.550   38.621  1.00 24.42  ? 91  VAL B CG2 1 
ATOM   3873  N  N   . HIS B 1 113 ? -37.334 5.095   34.836  1.00 24.28  ? 92  HIS B N   1 
ATOM   3874  C  CA  . HIS B 1 113 ? -38.144 4.788   33.643  1.00 21.92  ? 92  HIS B CA  1 
ATOM   3875  C  C   . HIS B 1 113 ? -37.699 3.491   32.995  1.00 26.82  ? 92  HIS B C   1 
ATOM   3876  O  O   . HIS B 1 113 ? -38.505 2.790   32.371  1.00 25.28  ? 92  HIS B O   1 
ATOM   3877  C  CB  . HIS B 1 113 ? -38.023 5.922   32.609  1.00 21.90  ? 92  HIS B CB  1 
ATOM   3878  C  CG  . HIS B 1 113 ? -38.350 7.283   33.151  1.00 23.88  ? 92  HIS B CG  1 
ATOM   3879  N  ND1 . HIS B 1 113 ? -37.583 7.918   34.117  1.00 24.12  ? 92  HIS B ND1 1 
ATOM   3880  C  CD2 . HIS B 1 113 ? -39.334 8.156   32.819  1.00 24.63  ? 92  HIS B CD2 1 
ATOM   3881  C  CE1 . HIS B 1 113 ? -38.109 9.103   34.382  1.00 21.39  ? 92  HIS B CE1 1 
ATOM   3882  N  NE2 . HIS B 1 113 ? -39.156 9.281   33.593  1.00 24.09  ? 92  HIS B NE2 1 
ATOM   3883  N  N   . ASN B 1 114 ? -36.422 3.163   33.134  1.00 25.34  ? 93  ASN B N   1 
ATOM   3884  C  CA  . ASN B 1 114 ? -35.808 2.028   32.472  1.00 28.02  ? 93  ASN B CA  1 
ATOM   3885  C  C   . ASN B 1 114 ? -35.830 0.773   33.314  1.00 28.08  ? 93  ASN B C   1 
ATOM   3886  O  O   . ASN B 1 114 ? -35.390 -0.277  32.830  1.00 31.19  ? 93  ASN B O   1 
ATOM   3887  C  CB  . ASN B 1 114 ? -34.347 2.351   32.117  1.00 32.93  ? 93  ASN B CB  1 
ATOM   3888  C  CG  . ASN B 1 114 ? -34.226 3.537   31.194  1.00 47.77  ? 93  ASN B CG  1 
ATOM   3889  O  OD1 . ASN B 1 114 ? -35.018 3.695   30.258  1.00 53.76  ? 93  ASN B OD1 1 
ATOM   3890  N  ND2 . ASN B 1 114 ? -33.232 4.391   31.452  1.00 58.66  ? 93  ASN B ND2 1 
ATOM   3891  N  N   . LEU B 1 115 ? -36.318 0.842   34.545  1.00 23.78  ? 94  LEU B N   1 
ATOM   3892  C  CA  . LEU B 1 115 ? -36.276 -0.314  35.434  1.00 25.34  ? 94  LEU B CA  1 
ATOM   3893  C  C   . LEU B 1 115 ? -37.542 -1.141  35.349  1.00 23.67  ? 94  LEU B C   1 
ATOM   3894  O  O   . LEU B 1 115 ? -38.613 -0.636  35.045  1.00 24.54  ? 94  LEU B O   1 
ATOM   3895  C  CB  . LEU B 1 115 ? -36.096 0.127   36.887  1.00 22.91  ? 94  LEU B CB  1 
ATOM   3896  C  CG  . LEU B 1 115 ? -34.890 1.030   37.116  1.00 26.60  ? 94  LEU B CG  1 
ATOM   3897  C  CD1 . LEU B 1 115 ? -34.883 1.472   38.565  1.00 26.67  ? 94  LEU B CD1 1 
ATOM   3898  C  CD2 . LEU B 1 115 ? -33.572 0.312   36.729  1.00 31.20  ? 94  LEU B CD2 1 
ATOM   3899  N  N   . ASP B 1 116 ? -37.424 -2.401  35.770  1.00 24.50  ? 95  ASP B N   1 
ATOM   3900  C  CA  . ASP B 1 116 ? -38.531 -3.348  35.802  1.00 23.82  ? 95  ASP B CA  1 
ATOM   3901  C  C   . ASP B 1 116 ? -38.512 -4.116  37.119  1.00 26.51  ? 95  ASP B C   1 
ATOM   3902  O  O   . ASP B 1 116 ? -37.535 -4.085  37.864  1.00 25.53  ? 95  ASP B O   1 
ATOM   3903  C  CB  . ASP B 1 116 ? -38.442 -4.337  34.622  1.00 24.39  ? 95  ASP B CB  1 
ATOM   3904  C  CG  . ASP B 1 116 ? -38.521 -3.643  33.276  1.00 31.35  ? 95  ASP B CG  1 
ATOM   3905  O  OD1 . ASP B 1 116 ? -39.575 -2.992  32.998  1.00 28.50  ? 95  ASP B OD1 1 
ATOM   3906  O  OD2 . ASP B 1 116 ? -37.516 -3.721  32.513  1.00 26.85  ? 95  ASP B OD2 1 
ATOM   3907  N  N   . GLY B 1 117 ? -39.610 -4.813  37.393  1.00 28.95  ? 96  GLY B N   1 
ATOM   3908  C  CA  . GLY B 1 117 ? -39.698 -5.723  38.522  1.00 28.50  ? 96  GLY B CA  1 
ATOM   3909  C  C   . GLY B 1 117 ? -39.529 -5.041  39.870  1.00 36.70  ? 96  GLY B C   1 
ATOM   3910  O  O   . GLY B 1 117 ? -39.874 -3.867  40.069  1.00 26.98  ? 96  GLY B O   1 
ATOM   3911  N  N   . GLU B 1 118 ? -38.962 -5.794  40.820  1.00 27.32  ? 97  GLU B N   1 
ATOM   3912  C  CA  . GLU B 1 118 ? -38.839 -5.305  42.193  1.00 27.04  ? 97  GLU B CA  1 
ATOM   3913  C  C   . GLU B 1 118 ? -37.913 -4.090  42.300  1.00 25.86  ? 97  GLU B C   1 
ATOM   3914  O  O   . GLU B 1 118 ? -38.173 -3.176  43.094  1.00 28.03  ? 97  GLU B O   1 
ATOM   3915  C  CB  . GLU B 1 118 ? -38.352 -6.442  43.098  1.00 32.71  ? 97  GLU B CB  1 
ATOM   3916  C  CG  . GLU B 1 118 ? -38.330 -6.097  44.595  1.00 45.06  ? 97  GLU B CG  1 
ATOM   3917  C  CD  . GLU B 1 118 ? -39.695 -5.705  45.147  1.00 57.33  ? 97  GLU B CD  1 
ATOM   3918  O  OE1 . GLU B 1 118 ? -40.741 -6.121  44.584  1.00 62.23  ? 97  GLU B OE1 1 
ATOM   3919  O  OE2 . GLU B 1 118 ? -39.717 -4.972  46.158  1.00 54.53  ? 97  GLU B OE2 1 
ATOM   3920  N  N   . GLU B 1 119 ? -36.842 -4.040  41.501  1.00 25.30  ? 98  GLU B N   1 
ATOM   3921  C  CA  . GLU B 1 119 ? -35.987 -2.860  41.527  1.00 24.50  ? 98  GLU B CA  1 
ATOM   3922  C  C   . GLU B 1 119 ? -36.761 -1.622  41.087  1.00 26.82  ? 98  GLU B C   1 
ATOM   3923  O  O   . GLU B 1 119 ? -36.579 -0.549  41.657  1.00 24.55  ? 98  GLU B O   1 
ATOM   3924  C  CB  . GLU B 1 119 ? -34.755 -3.044  40.642  1.00 35.73  ? 98  GLU B CB  1 
ATOM   3925  C  CG  . GLU B 1 119 ? -33.767 -4.108  41.139  1.00 41.50  ? 98  GLU B CG  1 
ATOM   3926  C  CD  . GLU B 1 119 ? -33.003 -3.723  42.414  1.00 48.06  ? 98  GLU B CD  1 
ATOM   3927  O  OE1 . GLU B 1 119 ? -33.301 -2.679  43.052  1.00 39.55  ? 98  GLU B OE1 1 
ATOM   3928  O  OE2 . GLU B 1 119 ? -32.084 -4.490  42.783  1.00 50.94  ? 98  GLU B OE2 1 
ATOM   3929  N  N   . HIS B 1 120 ? -37.608 -1.745  40.059  1.00 28.70  ? 99  HIS B N   1 
ATOM   3930  C  CA  . HIS B 1 120 ? -38.450 -0.604  39.701  1.00 24.29  ? 99  HIS B CA  1 
ATOM   3931  C  C   . HIS B 1 120 ? -39.390 -0.234  40.844  1.00 28.29  ? 99  HIS B C   1 
ATOM   3932  O  O   . HIS B 1 120 ? -39.556 0.947   41.175  1.00 27.17  ? 99  HIS B O   1 
ATOM   3933  C  CB  . HIS B 1 120 ? -39.282 -0.888  38.445  1.00 21.58  ? 99  HIS B CB  1 
ATOM   3934  C  CG  . HIS B 1 120 ? -40.284 0.201   38.185  1.00 23.44  ? 99  HIS B CG  1 
ATOM   3935  N  ND1 . HIS B 1 120 ? -41.623 0.075   38.514  1.00 24.82  ? 99  HIS B ND1 1 
ATOM   3936  C  CD2 . HIS B 1 120 ? -40.121 1.472   37.736  1.00 20.50  ? 99  HIS B CD2 1 
ATOM   3937  C  CE1 . HIS B 1 120 ? -42.250 1.203   38.232  1.00 25.19  ? 99  HIS B CE1 1 
ATOM   3938  N  NE2 . HIS B 1 120 ? -41.364 2.069   37.763  1.00 23.87  ? 99  HIS B NE2 1 
ATOM   3939  N  N   . LYS B 1 121 ? -40.039 -1.228  41.453  1.00 26.76  ? 100 LYS B N   1 
ATOM   3940  C  CA  . LYS B 1 121 ? -41.015 -0.909  42.490  1.00 25.68  ? 100 LYS B CA  1 
ATOM   3941  C  C   . LYS B 1 121 ? -40.349 -0.194  43.668  1.00 26.75  ? 100 LYS B C   1 
ATOM   3942  O  O   . LYS B 1 121 ? -40.913 0.747   44.237  1.00 27.10  ? 100 LYS B O   1 
ATOM   3943  C  CB  . LYS B 1 121 ? -41.731 -2.186  42.936  1.00 25.77  ? 100 LYS B CB  1 
ATOM   3944  C  CG  . LYS B 1 121 ? -42.774 -1.946  44.019  1.00 49.58  ? 100 LYS B CG  1 
ATOM   3945  C  CD  . LYS B 1 121 ? -43.815 -3.072  44.036  1.00 68.37  ? 100 LYS B CD  1 
ATOM   3946  C  CE  . LYS B 1 121 ? -45.017 -2.735  44.929  1.00 70.96  ? 100 LYS B CE  1 
ATOM   3947  N  NZ  . LYS B 1 121 ? -46.160 -3.677  44.715  1.00 60.30  ? 100 LYS B NZ  1 
ATOM   3948  N  N   . VAL B 1 122 ? -39.118 -0.579  43.996  1.00 25.79  ? 101 VAL B N   1 
ATOM   3949  C  CA  . VAL B 1 122 ? -38.430 0.021   45.141  1.00 30.40  ? 101 VAL B CA  1 
ATOM   3950  C  C   . VAL B 1 122 ? -38.020 1.453   44.831  1.00 29.35  ? 101 VAL B C   1 
ATOM   3951  O  O   . VAL B 1 122 ? -38.160 2.352   45.673  1.00 29.04  ? 101 VAL B O   1 
ATOM   3952  C  CB  . VAL B 1 122 ? -37.229 -0.854  45.539  1.00 30.57  ? 101 VAL B CB  1 
ATOM   3953  C  CG1 . VAL B 1 122 ? -36.218 -0.075  46.387  1.00 32.88  ? 101 VAL B CG1 1 
ATOM   3954  C  CG2 . VAL B 1 122 ? -37.741 -2.081  46.299  1.00 28.99  ? 101 VAL B CG2 1 
ATOM   3955  N  N   . ARG B 1 123 ? -37.520 1.686   43.621  1.00 23.19  ? 102 ARG B N   1 
ATOM   3956  C  CA  . ARG B 1 123 ? -37.125 3.020   43.195  1.00 25.60  ? 102 ARG B CA  1 
ATOM   3957  C  C   . ARG B 1 123 ? -38.340 3.924   43.049  1.00 27.39  ? 102 ARG B C   1 
ATOM   3958  O  O   . ARG B 1 123 ? -38.297 5.102   43.427  1.00 26.90  ? 102 ARG B O   1 
ATOM   3959  C  CB  . ARG B 1 123 ? -36.370 2.917   41.871  1.00 24.49  ? 102 ARG B CB  1 
ATOM   3960  C  CG  . ARG B 1 123 ? -36.048 4.247   41.154  1.00 29.70  ? 102 ARG B CG  1 
ATOM   3961  C  CD  . ARG B 1 123 ? -34.781 4.905   41.705  1.00 35.25  ? 102 ARG B CD  1 
ATOM   3962  N  NE  . ARG B 1 123 ? -33.642 3.997   41.607  1.00 30.25  ? 102 ARG B NE  1 
ATOM   3963  C  CZ  . ARG B 1 123 ? -32.815 3.936   40.578  1.00 31.07  ? 102 ARG B CZ  1 
ATOM   3964  N  NH1 . ARG B 1 123 ? -32.918 4.777   39.551  1.00 28.08  ? 102 ARG B NH1 1 
ATOM   3965  N  NH2 . ARG B 1 123 ? -31.864 2.998   40.570  1.00 29.73  ? 102 ARG B NH2 1 
ATOM   3966  N  N   . LYS B 1 124 ? -39.412 3.387   42.471  1.00 24.19  ? 103 LYS B N   1 
ATOM   3967  C  CA  . LYS B 1 124 ? -40.627 4.158   42.265  1.00 23.94  ? 103 LYS B CA  1 
ATOM   3968  C  C   . LYS B 1 124 ? -41.290 4.515   43.581  1.00 25.72  ? 103 LYS B C   1 
ATOM   3969  O  O   . LYS B 1 124 ? -41.862 5.606   43.697  1.00 25.04  ? 103 LYS B O   1 
ATOM   3970  C  CB  . LYS B 1 124 ? -41.598 3.379   41.371  1.00 25.46  ? 103 LYS B CB  1 
ATOM   3971  C  CG  . LYS B 1 124 ? -42.946 4.106   41.114  1.00 21.29  ? 103 LYS B CG  1 
ATOM   3972  C  CD  . LYS B 1 124 ? -42.669 5.470   40.470  1.00 24.07  ? 103 LYS B CD  1 
ATOM   3973  C  CE  . LYS B 1 124 ? -43.951 6.117   39.941  1.00 23.80  ? 103 LYS B CE  1 
ATOM   3974  N  NZ  . LYS B 1 124 ? -44.553 5.244   38.833  1.00 22.08  ? 103 LYS B NZ  1 
ATOM   3975  N  N   . ALA B 1 125 ? -41.202 3.626   44.583  1.00 26.16  ? 104 ALA B N   1 
ATOM   3976  C  CA  . ALA B 1 125 ? -41.759 3.943   45.891  1.00 28.86  ? 104 ALA B CA  1 
ATOM   3977  C  C   . ALA B 1 125 ? -41.101 5.181   46.484  1.00 28.61  ? 104 ALA B C   1 
ATOM   3978  O  O   . ALA B 1 125 ? -41.783 6.020   47.088  1.00 29.33  ? 104 ALA B O   1 
ATOM   3979  C  CB  . ALA B 1 125 ? -41.610 2.747   46.841  1.00 28.33  ? 104 ALA B CB  1 
ATOM   3980  N  N   . GLN B 1 126 ? -39.779 5.325   46.304  1.00 23.69  ? 105 GLN B N   1 
ATOM   3981  C  CA  . GLN B 1 126 ? -39.042 6.435   46.897  1.00 24.60  ? 105 GLN B CA  1 
ATOM   3982  C  C   . GLN B 1 126 ? -39.268 7.739   46.127  1.00 31.09  ? 105 GLN B C   1 
ATOM   3983  O  O   . GLN B 1 126 ? -39.259 8.831   46.716  1.00 32.72  ? 105 GLN B O   1 
ATOM   3984  C  CB  . GLN B 1 126 ? -37.560 6.083   46.954  1.00 26.16  ? 105 GLN B CB  1 
ATOM   3985  C  CG  . GLN B 1 126 ? -37.247 5.004   47.985  1.00 32.57  ? 105 GLN B CG  1 
ATOM   3986  C  CD  . GLN B 1 126 ? -35.846 4.491   47.823  1.00 32.21  ? 105 GLN B CD  1 
ATOM   3987  O  OE1 . GLN B 1 126 ? -34.880 5.105   48.313  1.00 27.24  ? 105 GLN B OE1 1 
ATOM   3988  N  NE2 . GLN B 1 126 ? -35.705 3.385   47.088  1.00 28.21  ? 105 GLN B NE2 1 
ATOM   3989  N  N   . MET B 1 127 ? -39.515 7.646   44.825  1.00 29.20  ? 106 MET B N   1 
ATOM   3990  C  CA  . MET B 1 127 ? -39.802 8.849   44.062  1.00 25.40  ? 106 MET B CA  1 
ATOM   3991  C  C   . MET B 1 127 ? -41.263 9.255   44.171  1.00 29.34  ? 106 MET B C   1 
ATOM   3992  O  O   . MET B 1 127 ? -41.558 10.448  44.266  1.00 30.01  ? 106 MET B O   1 
ATOM   3993  C  CB  . MET B 1 127 ? -39.363 8.629   42.629  1.00 30.54  ? 106 MET B CB  1 
ATOM   3994  C  CG  . MET B 1 127 ? -37.804 8.654   42.607  1.00 31.23  ? 106 MET B CG  1 
ATOM   3995  S  SD  . MET B 1 127 ? -37.240 8.169   41.020  1.00 40.63  ? 106 MET B SD  1 
ATOM   3996  C  CE  . MET B 1 127 ? -37.410 9.804   40.196  1.00 30.10  ? 106 MET B CE  1 
ATOM   3997  N  N   . ALA B 1 128 ? -42.192 8.291   44.198  1.00 25.17  ? 107 ALA B N   1 
ATOM   3998  C  CA  . ALA B 1 128 ? -43.585 8.642   44.448  1.00 29.20  ? 107 ALA B CA  1 
ATOM   3999  C  C   . ALA B 1 128 ? -43.757 9.233   45.846  1.00 32.09  ? 107 ALA B C   1 
ATOM   4000  O  O   . ALA B 1 128 ? -44.622 10.092  46.060  1.00 28.05  ? 107 ALA B O   1 
ATOM   4001  C  CB  . ALA B 1 128 ? -44.500 7.423   44.277  1.00 27.14  ? 107 ALA B CB  1 
ATOM   4002  N  N   . ALA B 1 129 ? -42.961 8.787   46.816  1.00 25.49  ? 108 ALA B N   1 
ATOM   4003  C  CA  . ALA B 1 129 ? -43.109 9.371   48.152  1.00 29.10  ? 108 ALA B CA  1 
ATOM   4004  C  C   . ALA B 1 129 ? -42.804 10.866  48.125  1.00 28.00  ? 108 ALA B C   1 
ATOM   4005  O  O   . ALA B 1 129 ? -43.331 11.623  48.948  1.00 33.37  ? 108 ALA B O   1 
ATOM   4006  C  CB  . ALA B 1 129 ? -42.200 8.652   49.161  1.00 33.15  ? 108 ALA B CB  1 
ATOM   4007  N  N   . MET B 1 130 ? -41.977 11.315  47.185  1.00 24.94  ? 109 MET B N   1 
ATOM   4008  C  CA  . MET B 1 130 ? -41.667 12.736  47.088  1.00 28.02  ? 109 MET B CA  1 
ATOM   4009  C  C   . MET B 1 130 ? -42.721 13.493  46.277  1.00 33.04  ? 109 MET B C   1 
ATOM   4010  O  O   . MET B 1 130 ? -43.182 14.556  46.698  1.00 30.50  ? 109 MET B O   1 
ATOM   4011  C  CB  . MET B 1 130 ? -40.277 12.936  46.476  1.00 21.67  ? 109 MET B CB  1 
ATOM   4012  C  CG  . MET B 1 130 ? -39.107 12.334  47.295  1.00 29.40  ? 109 MET B CG  1 
ATOM   4013  S  SD  . MET B 1 130 ? -39.109 12.973  49.016  1.00 30.31  ? 109 MET B SD  1 
ATOM   4014  C  CE  . MET B 1 130 ? -39.786 11.599  49.943  1.00 27.59  ? 109 MET B CE  1 
ATOM   4015  N  N   . ALA B 1 131 ? -43.101 12.982  45.096  1.00 26.06  ? 110 ALA B N   1 
ATOM   4016  C  CA  . ALA B 1 131 ? -43.953 13.770  44.201  1.00 29.19  ? 110 ALA B CA  1 
ATOM   4017  C  C   . ALA B 1 131 ? -45.444 13.572  44.424  1.00 24.65  ? 110 ALA B C   1 
ATOM   4018  O  O   . ALA B 1 131 ? -46.246 14.460  44.105  1.00 27.14  ? 110 ALA B O   1 
ATOM   4019  C  CB  . ALA B 1 131 ? -43.623 13.427  42.744  1.00 30.84  ? 110 ALA B CB  1 
ATOM   4020  N  N   . TYR B 1 132 ? -45.853 12.437  44.959  1.00 24.08  ? 111 TYR B N   1 
ATOM   4021  C  CA  . TYR B 1 132 ? -47.248 12.050  44.867  1.00 23.00  ? 111 TYR B CA  1 
ATOM   4022  C  C   . TYR B 1 132 ? -48.009 12.223  46.176  1.00 29.41  ? 111 TYR B C   1 
ATOM   4023  O  O   . TYR B 1 132 ? -49.243 12.217  46.153  1.00 30.25  ? 111 TYR B O   1 
ATOM   4024  C  CB  . TYR B 1 132 ? -47.321 10.601  44.397  1.00 27.47  ? 111 TYR B CB  1 
ATOM   4025  C  CG  . TYR B 1 132 ? -48.685 10.112  44.014  1.00 26.90  ? 111 TYR B CG  1 
ATOM   4026  C  CD1 . TYR B 1 132 ? -49.314 10.560  42.835  1.00 26.87  ? 111 TYR B CD1 1 
ATOM   4027  C  CD2 . TYR B 1 132 ? -49.333 9.160   44.785  1.00 31.25  ? 111 TYR B CD2 1 
ATOM   4028  C  CE1 . TYR B 1 132 ? -50.578 10.114  42.486  1.00 25.04  ? 111 TYR B CE1 1 
ATOM   4029  C  CE2 . TYR B 1 132 ? -50.582 8.687   44.424  1.00 31.31  ? 111 TYR B CE2 1 
ATOM   4030  C  CZ  . TYR B 1 132 ? -51.196 9.147   43.279  1.00 29.56  ? 111 TYR B CZ  1 
ATOM   4031  O  OH  . TYR B 1 132 ? -52.447 8.654   42.948  1.00 33.22  ? 111 TYR B OH  1 
ATOM   4032  N  N   . GLU B 1 133 ? -47.301 12.403  47.294  1.00 29.38  ? 112 GLU B N   1 
ATOM   4033  C  CA  . GLU B 1 133 ? -47.938 12.538  48.606  1.00 29.41  ? 112 GLU B CA  1 
ATOM   4034  C  C   . GLU B 1 133 ? -48.601 13.909  48.750  1.00 28.17  ? 112 GLU B C   1 
ATOM   4035  O  O   . GLU B 1 133 ? -47.986 14.944  48.471  1.00 25.80  ? 112 GLU B O   1 
ATOM   4036  C  CB  . GLU B 1 133 ? -46.897 12.334  49.717  1.00 36.90  ? 112 GLU B CB  1 
ATOM   4037  C  CG  . GLU B 1 133 ? -46.503 10.859  49.949  1.00 41.20  ? 112 GLU B CG  1 
ATOM   4038  C  CD  . GLU B 1 133 ? -45.397 10.670  51.005  1.00 58.26  ? 112 GLU B CD  1 
ATOM   4039  O  OE1 . GLU B 1 133 ? -44.948 11.663  51.627  1.00 53.65  ? 112 GLU B OE1 1 
ATOM   4040  O  OE2 . GLU B 1 133 ? -44.965 9.511   51.207  1.00 51.46  ? 112 GLU B OE2 1 
ATOM   4041  N  N   . ASP B 1 134 ? -49.857 13.919  49.204  1.00 28.60  ? 113 ASP B N   1 
ATOM   4042  C  CA  . ASP B 1 134 ? -50.618 15.165  49.228  1.00 31.17  ? 113 ASP B CA  1 
ATOM   4043  C  C   . ASP B 1 134 ? -49.923 16.242  50.062  1.00 32.24  ? 113 ASP B C   1 
ATOM   4044  O  O   . ASP B 1 134 ? -49.945 17.423  49.700  1.00 29.54  ? 113 ASP B O   1 
ATOM   4045  C  CB  . ASP B 1 134 ? -52.040 14.915  49.749  1.00 29.13  ? 113 ASP B CB  1 
ATOM   4046  C  CG  . ASP B 1 134 ? -52.913 14.145  48.751  1.00 41.28  ? 113 ASP B CG  1 
ATOM   4047  O  OD1 . ASP B 1 134 ? -52.659 14.220  47.521  1.00 37.16  ? 113 ASP B OD1 1 
ATOM   4048  O  OD2 . ASP B 1 134 ? -53.864 13.461  49.199  1.00 47.13  ? 113 ASP B OD2 1 
ATOM   4049  N  N   . GLU B 1 135 ? -49.311 15.862  51.179  1.00 28.91  ? 114 GLU B N   1 
ATOM   4050  C  CA  . GLU B 1 135 ? -48.634 16.858  52.012  1.00 31.37  ? 114 GLU B CA  1 
ATOM   4051  C  C   . GLU B 1 135 ? -47.470 17.522  51.278  1.00 28.80  ? 114 GLU B C   1 
ATOM   4052  O  O   . GLU B 1 135 ? -47.168 18.697  51.511  1.00 35.24  ? 114 GLU B O   1 
ATOM   4053  C  CB  . GLU B 1 135 ? -48.151 16.194  53.309  1.00 38.36  ? 114 GLU B CB  1 
ATOM   4054  C  CG  . GLU B 1 135 ? -47.318 14.926  53.071  1.00 60.07  ? 114 GLU B CG  1 
ATOM   4055  C  CD  . GLU B 1 135 ? -48.106 13.588  53.127  1.00 73.08  ? 114 GLU B CD  1 
ATOM   4056  O  OE1 . GLU B 1 135 ? -49.246 13.470  52.590  1.00 44.81  ? 114 GLU B OE1 1 
ATOM   4057  O  OE2 . GLU B 1 135 ? -47.547 12.628  53.713  1.00 80.68  ? 114 GLU B OE2 1 
ATOM   4058  N  N   . ARG B 1 136 ? -46.803 16.798  50.386  1.00 28.84  ? 115 ARG B N   1 
ATOM   4059  C  CA  . ARG B 1 136 ? -45.698 17.409  49.661  1.00 27.59  ? 115 ARG B CA  1 
ATOM   4060  C  C   . ARG B 1 136 ? -46.191 18.277  48.516  1.00 25.66  ? 115 ARG B C   1 
ATOM   4061  O  O   . ARG B 1 136 ? -45.581 19.309  48.217  1.00 29.77  ? 115 ARG B O   1 
ATOM   4062  C  CB  . ARG B 1 136 ? -44.737 16.327  49.153  1.00 26.74  ? 115 ARG B CB  1 
ATOM   4063  C  CG  . ARG B 1 136 ? -44.051 15.656  50.332  1.00 34.86  ? 115 ARG B CG  1 
ATOM   4064  C  CD  . ARG B 1 136 ? -42.947 14.745  49.930  1.00 37.37  ? 115 ARG B CD  1 
ATOM   4065  N  NE  . ARG B 1 136 ? -42.339 14.101  51.087  1.00 32.79  ? 115 ARG B NE  1 
ATOM   4066  C  CZ  . ARG B 1 136 ? -41.252 14.553  51.706  1.00 39.65  ? 115 ARG B CZ  1 
ATOM   4067  N  NH1 . ARG B 1 136 ? -40.662 15.683  51.341  1.00 35.63  ? 115 ARG B NH1 1 
ATOM   4068  N  NH2 . ARG B 1 136 ? -40.739 13.851  52.708  1.00 35.59  ? 115 ARG B NH2 1 
ATOM   4069  N  N   . VAL B 1 137 ? -47.288 17.876  47.876  1.00 26.66  ? 116 VAL B N   1 
ATOM   4070  C  CA  . VAL B 1 137 ? -47.917 18.726  46.877  1.00 27.09  ? 116 VAL B CA  1 
ATOM   4071  C  C   . VAL B 1 137 ? -48.382 20.038  47.507  1.00 25.55  ? 116 VAL B C   1 
ATOM   4072  O  O   . VAL B 1 137 ? -48.207 21.124  46.926  1.00 24.81  ? 116 VAL B O   1 
ATOM   4073  C  CB  . VAL B 1 137 ? -49.076 17.959  46.215  1.00 24.51  ? 116 VAL B CB  1 
ATOM   4074  C  CG1 . VAL B 1 137 ? -49.816 18.855  45.229  1.00 27.31  ? 116 VAL B CG1 1 
ATOM   4075  C  CG2 . VAL B 1 137 ? -48.516 16.689  45.518  1.00 24.22  ? 116 VAL B CG2 1 
ATOM   4076  N  N   . ALA B 1 138 ? -48.981 19.963  48.709  1.00 27.12  ? 117 ALA B N   1 
ATOM   4077  C  CA  . ALA B 1 138 ? -49.389 21.179  49.408  1.00 28.29  ? 117 ALA B CA  1 
ATOM   4078  C  C   . ALA B 1 138 ? -48.209 22.088  49.742  1.00 25.53  ? 117 ALA B C   1 
ATOM   4079  O  O   . ALA B 1 138 ? -48.395 23.305  49.864  1.00 29.75  ? 117 ALA B O   1 
ATOM   4080  C  CB  . ALA B 1 138 ? -50.173 20.826  50.686  1.00 29.62  ? 117 ALA B CB  1 
ATOM   4081  N  N   . GLU B 1 139 ? -46.993 21.544  49.915  1.00 23.46  ? 118 GLU B N   1 
ATOM   4082  C  CA  . GLU B 1 139 ? -45.836 22.421  50.084  1.00 28.10  ? 118 GLU B CA  1 
ATOM   4083  C  C   . GLU B 1 139 ? -45.467 23.111  48.768  1.00 31.71  ? 118 GLU B C   1 
ATOM   4084  O  O   . GLU B 1 139 ? -44.929 24.228  48.773  1.00 27.58  ? 118 GLU B O   1 
ATOM   4085  C  CB  . GLU B 1 139 ? -44.617 21.648  50.584  1.00 32.21  ? 118 GLU B CB  1 
ATOM   4086  C  CG  . GLU B 1 139 ? -44.769 20.987  51.942  1.00 37.34  ? 118 GLU B CG  1 
ATOM   4087  C  CD  . GLU B 1 139 ? -43.613 20.030  52.253  1.00 51.94  ? 118 GLU B CD  1 
ATOM   4088  O  OE1 . GLU B 1 139 ? -42.575 20.066  51.541  1.00 53.07  ? 118 GLU B OE1 1 
ATOM   4089  O  OE2 . GLU B 1 139 ? -43.750 19.232  53.207  1.00 69.09  ? 118 GLU B OE2 1 
ATOM   4090  N  N   . PHE B 1 140 ? -45.722 22.438  47.639  1.00 28.04  ? 119 PHE B N   1 
ATOM   4091  C  CA  . PHE B 1 140 ? -45.381 22.986  46.331  1.00 23.75  ? 119 PHE B CA  1 
ATOM   4092  C  C   . PHE B 1 140 ? -46.333 24.109  45.942  1.00 23.73  ? 119 PHE B C   1 
ATOM   4093  O  O   . PHE B 1 140 ? -45.910 25.082  45.324  1.00 24.77  ? 119 PHE B O   1 
ATOM   4094  C  CB  . PHE B 1 140 ? -45.402 21.860  45.278  1.00 25.23  ? 119 PHE B CB  1 
ATOM   4095  C  CG  . PHE B 1 140 ? -45.104 22.337  43.882  1.00 21.58  ? 119 PHE B CG  1 
ATOM   4096  C  CD1 . PHE B 1 140 ? -43.823 22.695  43.526  1.00 24.01  ? 119 PHE B CD1 1 
ATOM   4097  C  CD2 . PHE B 1 140 ? -46.118 22.461  42.946  1.00 25.67  ? 119 PHE B CD2 1 
ATOM   4098  C  CE1 . PHE B 1 140 ? -43.526 23.152  42.250  1.00 23.28  ? 119 PHE B CE1 1 
ATOM   4099  C  CE2 . PHE B 1 140 ? -45.838 22.917  41.643  1.00 19.81  ? 119 PHE B CE2 1 
ATOM   4100  C  CZ  . PHE B 1 140 ? -44.554 23.266  41.301  1.00 20.85  ? 119 PHE B CZ  1 
ATOM   4101  N  N   . ALA B 1 141 ? -47.621 24.006  46.310  1.00 23.95  ? 120 ALA B N   1 
ATOM   4102  C  CA  . ALA B 1 141 ? -48.616 24.962  45.821  1.00 26.53  ? 120 ALA B CA  1 
ATOM   4103  C  C   . ALA B 1 141 ? -48.276 26.423  46.136  1.00 29.47  ? 120 ALA B C   1 
ATOM   4104  O  O   . ALA B 1 141 ? -48.325 27.251  45.207  1.00 27.01  ? 120 ALA B O   1 
ATOM   4105  C  CB  . ALA B 1 141 ? -50.021 24.571  46.328  1.00 23.59  ? 120 ALA B CB  1 
ATOM   4106  N  N   . PRO B 1 142 ? -47.917 26.817  47.366  1.00 29.19  ? 121 PRO B N   1 
ATOM   4107  C  CA  . PRO B 1 142 ? -47.642 28.252  47.584  1.00 26.67  ? 121 PRO B CA  1 
ATOM   4108  C  C   . PRO B 1 142 ? -46.370 28.714  46.900  1.00 30.76  ? 121 PRO B C   1 
ATOM   4109  O  O   . PRO B 1 142 ? -46.305 29.883  46.500  1.00 30.63  ? 121 PRO B O   1 
ATOM   4110  C  CB  . PRO B 1 142 ? -47.551 28.384  49.117  1.00 28.00  ? 121 PRO B CB  1 
ATOM   4111  C  CG  . PRO B 1 142 ? -47.112 27.010  49.600  1.00 27.19  ? 121 PRO B CG  1 
ATOM   4112  C  CD  . PRO B 1 142 ? -47.889 26.057  48.634  1.00 26.32  ? 121 PRO B CD  1 
ATOM   4113  N  N   . LEU B 1 143 ? -45.386 27.820  46.718  1.00 27.01  ? 122 LEU B N   1 
ATOM   4114  C  CA  . LEU B 1 143 ? -44.137 28.179  46.049  1.00 21.99  ? 122 LEU B CA  1 
ATOM   4115  C  C   . LEU B 1 143 ? -44.356 28.478  44.573  1.00 26.82  ? 122 LEU B C   1 
ATOM   4116  O  O   . LEU B 1 143 ? -43.813 29.452  44.036  1.00 23.28  ? 122 LEU B O   1 
ATOM   4117  C  CB  . LEU B 1 143 ? -43.123 27.038  46.198  1.00 25.74  ? 122 LEU B CB  1 
ATOM   4118  C  CG  . LEU B 1 143 ? -42.717 26.685  47.638  1.00 34.76  ? 122 LEU B CG  1 
ATOM   4119  C  CD1 . LEU B 1 143 ? -41.980 25.361  47.690  1.00 30.26  ? 122 LEU B CD1 1 
ATOM   4120  C  CD2 . LEU B 1 143 ? -41.827 27.802  48.235  1.00 36.20  ? 122 LEU B CD2 1 
ATOM   4121  N  N   . VAL B 1 144 ? -45.106 27.619  43.882  1.00 23.85  ? 123 VAL B N   1 
ATOM   4122  C  CA  . VAL B 1 144 ? -45.293 27.882  42.464  1.00 22.55  ? 123 VAL B CA  1 
ATOM   4123  C  C   . VAL B 1 144 ? -46.203 29.089  42.249  1.00 27.22  ? 123 VAL B C   1 
ATOM   4124  O  O   . VAL B 1 144 ? -46.000 29.841  41.297  1.00 25.01  ? 123 VAL B O   1 
ATOM   4125  C  CB  . VAL B 1 144 ? -45.817 26.617  41.749  1.00 20.78  ? 123 VAL B CB  1 
ATOM   4126  C  CG1 . VAL B 1 144 ? -47.305 26.338  42.087  1.00 21.59  ? 123 VAL B CG1 1 
ATOM   4127  C  CG2 . VAL B 1 144 ? -45.607 26.760  40.248  1.00 22.01  ? 123 VAL B CG2 1 
ATOM   4128  N  N   . ALA B 1 145 ? -47.193 29.323  43.128  1.00 25.42  ? 124 ALA B N   1 
ATOM   4129  C  CA  . ALA B 1 145 ? -47.974 30.563  43.055  1.00 27.46  ? 124 ALA B CA  1 
ATOM   4130  C  C   . ALA B 1 145 ? -47.071 31.791  43.142  1.00 26.07  ? 124 ALA B C   1 
ATOM   4131  O  O   . ALA B 1 145 ? -47.178 32.728  42.336  1.00 28.43  ? 124 ALA B O   1 
ATOM   4132  C  CB  . ALA B 1 145 ? -49.030 30.596  44.168  1.00 29.39  ? 124 ALA B CB  1 
ATOM   4133  N  N   . GLU B 1 146 ? -46.133 31.769  44.079  1.00 25.80  ? 125 GLU B N   1 
ATOM   4134  C  CA  . GLU B 1 146 ? -45.239 32.896  44.271  1.00 26.46  ? 125 GLU B CA  1 
ATOM   4135  C  C   . GLU B 1 146 ? -44.313 33.097  43.077  1.00 32.72  ? 125 GLU B C   1 
ATOM   4136  O  O   . GLU B 1 146 ? -44.085 34.235  42.649  1.00 27.21  ? 125 GLU B O   1 
ATOM   4137  C  CB  . GLU B 1 146 ? -44.455 32.679  45.568  1.00 34.65  ? 125 GLU B CB  1 
ATOM   4138  C  CG  . GLU B 1 146 ? -43.327 33.627  45.844  1.00 48.79  ? 125 GLU B CG  1 
ATOM   4139  C  CD  . GLU B 1 146 ? -42.515 33.182  47.070  1.00 65.55  ? 125 GLU B CD  1 
ATOM   4140  O  OE1 . GLU B 1 146 ? -42.876 32.139  47.677  1.00 54.53  ? 125 GLU B OE1 1 
ATOM   4141  O  OE2 . GLU B 1 146 ? -41.521 33.863  47.420  1.00 68.39  ? 125 GLU B OE2 1 
ATOM   4142  N  N   . GLU B 1 147 ? -43.776 32.013  42.510  1.00 24.65  ? 126 GLU B N   1 
ATOM   4143  C  CA  . GLU B 1 147 ? -42.873 32.169  41.372  1.00 25.32  ? 126 GLU B CA  1 
ATOM   4144  C  C   . GLU B 1 147 ? -43.629 32.580  40.119  1.00 28.41  ? 126 GLU B C   1 
ATOM   4145  O  O   . GLU B 1 147 ? -43.093 33.330  39.290  1.00 23.72  ? 126 GLU B O   1 
ATOM   4146  C  CB  . GLU B 1 147 ? -42.096 30.869  41.121  1.00 28.17  ? 126 GLU B CB  1 
ATOM   4147  C  CG  . GLU B 1 147 ? -41.168 30.484  42.274  1.00 27.70  ? 126 GLU B CG  1 
ATOM   4148  C  CD  . GLU B 1 147 ? -40.064 31.524  42.537  1.00 35.47  ? 126 GLU B CD  1 
ATOM   4149  O  OE1 . GLU B 1 147 ? -39.811 32.420  41.698  1.00 31.88  ? 126 GLU B OE1 1 
ATOM   4150  O  OE2 . GLU B 1 147 ? -39.422 31.422  43.599  1.00 34.87  ? 126 GLU B OE2 1 
ATOM   4151  N  N   . VAL B 1 148 ? -44.858 32.084  39.945  1.00 21.78  ? 127 VAL B N   1 
ATOM   4152  C  CA  . VAL B 1 148 ? -45.661 32.531  38.811  1.00 21.37  ? 127 VAL B CA  1 
ATOM   4153  C  C   . VAL B 1 148 ? -45.994 34.016  38.947  1.00 25.31  ? 127 VAL B C   1 
ATOM   4154  O  O   . VAL B 1 148 ? -45.922 34.780  37.974  1.00 23.93  ? 127 VAL B O   1 
ATOM   4155  C  CB  . VAL B 1 148 ? -46.938 31.676  38.698  1.00 22.79  ? 127 VAL B CB  1 
ATOM   4156  C  CG1 . VAL B 1 148 ? -48.000 32.373  37.860  1.00 21.10  ? 127 VAL B CG1 1 
ATOM   4157  C  CG2 . VAL B 1 148 ? -46.604 30.303  38.101  1.00 22.67  ? 127 VAL B CG2 1 
ATOM   4158  N  N   . GLU B 1 149 ? -46.331 34.451  40.163  1.00 26.58  ? 128 GLU B N   1 
ATOM   4159  C  CA  . GLU B 1 149 ? -46.659 35.857  40.380  1.00 29.72  ? 128 GLU B CA  1 
ATOM   4160  C  C   . GLU B 1 149 ? -45.467 36.740  40.051  1.00 28.77  ? 128 GLU B C   1 
ATOM   4161  O  O   . GLU B 1 149 ? -45.615 37.816  39.471  1.00 26.46  ? 128 GLU B O   1 
ATOM   4162  C  CB  . GLU B 1 149 ? -47.105 36.063  41.825  1.00 30.91  ? 128 GLU B CB  1 
ATOM   4163  C  CG  . GLU B 1 149 ? -47.385 37.522  42.163  1.00 53.93  ? 128 GLU B CG  1 
ATOM   4164  C  CD  . GLU B 1 149 ? -47.227 37.830  43.647  1.00 89.06  ? 128 GLU B CD  1 
ATOM   4165  O  OE1 . GLU B 1 149 ? -47.463 36.927  44.485  1.00 86.17  ? 128 GLU B OE1 1 
ATOM   4166  O  OE2 . GLU B 1 149 ? -46.855 38.981  43.975  1.00 99.73  ? 128 GLU B OE2 1 
ATOM   4167  N  N   . ARG B 1 150 ? -44.274 36.281  40.402  1.00 25.54  ? 129 ARG B N   1 
ATOM   4168  C  CA  . ARG B 1 150 ? -43.053 37.008  40.094  1.00 31.72  ? 129 ARG B CA  1 
ATOM   4169  C  C   . ARG B 1 150 ? -42.797 37.105  38.585  1.00 35.86  ? 129 ARG B C   1 
ATOM   4170  O  O   . ARG B 1 150 ? -42.376 38.161  38.083  1.00 29.47  ? 129 ARG B O   1 
ATOM   4171  C  CB  . ARG B 1 150 ? -41.908 36.312  40.828  1.00 29.57  ? 129 ARG B CB  1 
ATOM   4172  C  CG  . ARG B 1 150 ? -40.585 36.938  40.658  1.00 47.67  ? 129 ARG B CG  1 
ATOM   4173  C  CD  . ARG B 1 150 ? -39.558 36.182  41.501  1.00 49.34  ? 129 ARG B CD  1 
ATOM   4174  N  NE  . ARG B 1 150 ? -38.206 36.516  41.079  1.00 55.23  ? 129 ARG B NE  1 
ATOM   4175  C  CZ  . ARG B 1 150 ? -37.152 35.741  41.283  1.00 69.97  ? 129 ARG B CZ  1 
ATOM   4176  N  NH1 . ARG B 1 150 ? -37.269 34.559  41.875  1.00 47.54  ? 129 ARG B NH1 1 
ATOM   4177  N  NH2 . ARG B 1 150 ? -35.951 36.160  40.884  1.00 72.91  ? 129 ARG B NH2 1 
ATOM   4178  N  N   . ALA B 1 151 ? -43.026 36.021  37.834  1.00 24.55  ? 130 ALA B N   1 
ATOM   4179  C  CA  . ALA B 1 151 ? -42.799 36.089  36.390  1.00 25.52  ? 130 ALA B CA  1 
ATOM   4180  C  C   . ALA B 1 151 ? -43.786 37.035  35.732  1.00 25.04  ? 130 ALA B C   1 
ATOM   4181  O  O   . ALA B 1 151 ? -43.403 37.823  34.862  1.00 29.06  ? 130 ALA B O   1 
ATOM   4182  C  CB  . ALA B 1 151 ? -42.907 34.693  35.740  1.00 24.19  ? 130 ALA B CB  1 
ATOM   4183  N  N   . VAL B 1 152 ? -45.058 36.984  36.154  1.00 25.53  ? 131 VAL B N   1 
ATOM   4184  C  CA  . VAL B 1 152 ? -46.090 37.840  35.573  1.00 27.14  ? 131 VAL B CA  1 
ATOM   4185  C  C   . VAL B 1 152 ? -45.825 39.303  35.923  1.00 30.07  ? 131 VAL B C   1 
ATOM   4186  O  O   . VAL B 1 152 ? -46.030 40.196  35.094  1.00 31.62  ? 131 VAL B O   1 
ATOM   4187  C  CB  . VAL B 1 152 ? -47.488 37.376  36.037  1.00 28.75  ? 131 VAL B CB  1 
ATOM   4188  C  CG1 . VAL B 1 152 ? -48.550 38.300  35.511  1.00 36.19  ? 131 VAL B CG1 1 
ATOM   4189  C  CG2 . VAL B 1 152 ? -47.749 35.960  35.514  1.00 27.63  ? 131 VAL B CG2 1 
ATOM   4190  N  N   . ALA B 1 153 ? -45.344 39.569  37.145  1.00 28.90  ? 132 ALA B N   1 
ATOM   4191  C  CA  . ALA B 1 153 ? -44.929 40.933  37.479  1.00 39.09  ? 132 ALA B CA  1 
ATOM   4192  C  C   . ALA B 1 153 ? -43.842 41.442  36.530  1.00 34.21  ? 132 ALA B C   1 
ATOM   4193  O  O   . ALA B 1 153 ? -43.796 42.644  36.222  1.00 28.54  ? 132 ALA B O   1 
ATOM   4194  C  CB  . ALA B 1 153 ? -44.446 40.997  38.933  1.00 33.95  ? 132 ALA B CB  1 
ATOM   4195  N  N   . GLY B 1 154 ? -42.961 40.548  36.058  1.00 28.88  ? 133 GLY B N   1 
ATOM   4196  C  CA  . GLY B 1 154 ? -41.913 40.927  35.118  1.00 28.76  ? 133 GLY B CA  1 
ATOM   4197  C  C   . GLY B 1 154 ? -42.434 41.339  33.759  1.00 30.62  ? 133 GLY B C   1 
ATOM   4198  O  O   . GLY B 1 154 ? -41.703 41.958  32.970  1.00 29.05  ? 133 GLY B O   1 
ATOM   4199  N  N   . TRP B 1 155 ? -43.685 41.018  33.470  1.00 25.66  ? 134 TRP B N   1 
ATOM   4200  C  CA  . TRP B 1 155 ? -44.267 41.371  32.200  1.00 25.07  ? 134 TRP B CA  1 
ATOM   4201  C  C   . TRP B 1 155 ? -44.862 42.772  32.194  1.00 24.63  ? 134 TRP B C   1 
ATOM   4202  O  O   . TRP B 1 155 ? -45.317 43.219  31.146  1.00 25.74  ? 134 TRP B O   1 
ATOM   4203  C  CB  . TRP B 1 155 ? -45.355 40.358  31.827  1.00 24.73  ? 134 TRP B CB  1 
ATOM   4204  C  CG  . TRP B 1 155 ? -44.877 38.954  31.655  1.00 23.59  ? 134 TRP B CG  1 
ATOM   4205  C  CD1 . TRP B 1 155 ? -43.582 38.522  31.502  1.00 25.80  ? 134 TRP B CD1 1 
ATOM   4206  C  CD2 . TRP B 1 155 ? -45.701 37.775  31.656  1.00 25.37  ? 134 TRP B CD2 1 
ATOM   4207  N  NE1 . TRP B 1 155 ? -43.559 37.144  31.374  1.00 27.07  ? 134 TRP B NE1 1 
ATOM   4208  C  CE2 . TRP B 1 155 ? -44.844 36.665  31.481  1.00 27.36  ? 134 TRP B CE2 1 
ATOM   4209  C  CE3 . TRP B 1 155 ? -47.093 37.553  31.796  1.00 24.67  ? 134 TRP B CE3 1 
ATOM   4210  C  CZ2 . TRP B 1 155 ? -45.326 35.347  31.420  1.00 28.45  ? 134 TRP B CZ2 1 
ATOM   4211  C  CZ3 . TRP B 1 155 ? -47.573 36.234  31.716  1.00 27.94  ? 134 TRP B CZ3 1 
ATOM   4212  C  CH2 . TRP B 1 155 ? -46.682 35.151  31.551  1.00 26.87  ? 134 TRP B CH2 1 
ATOM   4213  N  N   . GLU B 1 156 ? -44.923 43.449  33.335  1.00 25.79  ? 135 GLU B N   1 
ATOM   4214  C  CA  . GLU B 1 156 ? -45.612 44.733  33.367  1.00 30.74  ? 135 GLU B CA  1 
ATOM   4215  C  C   . GLU B 1 156 ? -44.888 45.723  32.476  1.00 29.67  ? 135 GLU B C   1 
ATOM   4216  O  O   . GLU B 1 156 ? -43.724 46.029  32.713  1.00 30.27  ? 135 GLU B O   1 
ATOM   4217  C  CB  . GLU B 1 156 ? -45.706 45.242  34.804  1.00 30.69  ? 135 GLU B CB  1 
ATOM   4218  C  CG  . GLU B 1 156 ? -46.562 44.267  35.623  1.00 42.02  ? 135 GLU B CG  1 
ATOM   4219  C  CD  . GLU B 1 156 ? -46.673 44.570  37.118  1.00 50.91  ? 135 GLU B CD  1 
ATOM   4220  O  OE1 . GLU B 1 156 ? -45.826 45.307  37.661  1.00 57.40  ? 135 GLU B OE1 1 
ATOM   4221  O  OE2 . GLU B 1 156 ? -47.619 44.025  37.745  1.00 49.64  ? 135 GLU B OE2 1 
ATOM   4222  N  N   . GLY B 1 157 ? -45.569 46.185  31.430  1.00 30.79  ? 136 GLY B N   1 
ATOM   4223  C  CA  . GLY B 1 157 ? -44.963 47.139  30.522  1.00 37.26  ? 136 GLY B CA  1 
ATOM   4224  C  C   . GLY B 1 157 ? -43.773 46.613  29.759  1.00 41.34  ? 136 GLY B C   1 
ATOM   4225  O  O   . GLY B 1 157 ? -42.967 47.406  29.273  1.00 41.64  ? 136 GLY B O   1 
ATOM   4226  N  N   . ALA B 1 158 ? -43.658 45.292  29.615  1.00 28.99  ? 137 ALA B N   1 
ATOM   4227  C  CA  . ALA B 1 158 ? -42.474 44.650  29.068  1.00 31.49  ? 137 ALA B CA  1 
ATOM   4228  C  C   . ALA B 1 158 ? -42.913 43.510  28.151  1.00 34.34  ? 137 ALA B C   1 
ATOM   4229  O  O   . ALA B 1 158 ? -44.067 43.089  28.176  1.00 35.38  ? 137 ALA B O   1 
ATOM   4230  C  CB  . ALA B 1 158 ? -41.565 44.129  30.195  1.00 29.19  ? 137 ALA B CB  1 
ATOM   4231  N  N   . GLN B 1 159 ? -41.990 43.012  27.331  1.00 30.49  ? 138 GLN B N   1 
ATOM   4232  C  CA  . GLN B 1 159 ? -42.316 41.943  26.389  1.00 29.44  ? 138 GLN B CA  1 
ATOM   4233  C  C   . GLN B 1 159 ? -41.960 40.622  27.064  1.00 32.56  ? 138 GLN B C   1 
ATOM   4234  O  O   . GLN B 1 159 ? -40.784 40.337  27.306  1.00 31.08  ? 138 GLN B O   1 
ATOM   4235  C  CB  . GLN B 1 159 ? -41.575 42.102  25.062  1.00 38.35  ? 138 GLN B CB  1 
ATOM   4236  C  CG  . GLN B 1 159 ? -42.049 41.083  24.023  1.00 69.36  ? 138 GLN B CG  1 
ATOM   4237  C  CD  . GLN B 1 159 ? -41.826 41.527  22.586  1.00 78.64  ? 138 GLN B CD  1 
ATOM   4238  O  OE1 . GLN B 1 159 ? -41.636 42.717  22.296  1.00 81.25  ? 138 GLN B OE1 1 
ATOM   4239  N  NE2 . GLN B 1 159 ? -41.850 40.564  21.673  1.00 56.35  ? 138 GLN B NE2 1 
ATOM   4240  N  N   . GLY B 1 160 ? -42.977 39.827  27.383  1.00 28.08  ? 139 GLY B N   1 
ATOM   4241  C  CA  . GLY B 1 160 ? -42.788 38.550  28.032  1.00 25.86  ? 139 GLY B CA  1 
ATOM   4242  C  C   . GLY B 1 160 ? -43.017 37.388  27.084  1.00 25.40  ? 139 GLY B C   1 
ATOM   4243  O  O   . GLY B 1 160 ? -43.460 37.534  25.940  1.00 25.49  ? 139 GLY B O   1 
ATOM   4244  N  N   . ASN B 1 161 ? -42.751 36.199  27.612  1.00 23.42  ? 140 ASN B N   1 
ATOM   4245  C  CA  . ASN B 1 161 ? -42.813 34.977  26.827  1.00 23.52  ? 140 ASN B CA  1 
ATOM   4246  C  C   . ASN B 1 161 ? -43.354 33.888  27.742  1.00 23.00  ? 140 ASN B C   1 
ATOM   4247  O  O   . ASN B 1 161 ? -42.705 33.573  28.734  1.00 23.93  ? 140 ASN B O   1 
ATOM   4248  C  CB  . ASN B 1 161 ? -41.414 34.621  26.324  1.00 22.77  ? 140 ASN B CB  1 
ATOM   4249  C  CG  . ASN B 1 161 ? -41.447 33.494  25.335  1.00 30.22  ? 140 ASN B CG  1 
ATOM   4250  O  OD1 . ASN B 1 161 ? -41.543 32.330  25.712  1.00 25.18  ? 140 ASN B OD1 1 
ATOM   4251  N  ND2 . ASN B 1 161 ? -41.371 33.837  24.054  1.00 34.22  ? 140 ASN B ND2 1 
ATOM   4252  N  N   . VAL B 1 162 ? -44.544 33.330  27.442  1.00 20.02  ? 141 VAL B N   1 
ATOM   4253  C  CA  . VAL B 1 162 ? -45.125 32.372  28.381  1.00 22.38  ? 141 VAL B CA  1 
ATOM   4254  C  C   . VAL B 1 162 ? -44.201 31.178  28.559  1.00 23.54  ? 141 VAL B C   1 
ATOM   4255  O  O   . VAL B 1 162 ? -43.912 30.752  29.684  1.00 23.51  ? 141 VAL B O   1 
ATOM   4256  C  CB  . VAL B 1 162 ? -46.526 31.925  27.932  1.00 21.55  ? 141 VAL B CB  1 
ATOM   4257  C  CG1 . VAL B 1 162 ? -47.110 30.936  28.992  1.00 19.31  ? 141 VAL B CG1 1 
ATOM   4258  C  CG2 . VAL B 1 162 ? -47.459 33.107  27.810  1.00 18.34  ? 141 VAL B CG2 1 
ATOM   4259  N  N   . PHE B 1 163 ? -43.780 30.566  27.452  1.00 21.43  ? 142 PHE B N   1 
ATOM   4260  C  CA  . PHE B 1 163 ? -42.988 29.343  27.564  1.00 20.77  ? 142 PHE B CA  1 
ATOM   4261  C  C   . PHE B 1 163 ? -41.698 29.585  28.340  1.00 20.01  ? 142 PHE B C   1 
ATOM   4262  O  O   . PHE B 1 163 ? -41.394 28.857  29.281  1.00 22.85  ? 142 PHE B O   1 
ATOM   4263  C  CB  . PHE B 1 163 ? -42.656 28.779  26.190  1.00 21.32  ? 142 PHE B CB  1 
ATOM   4264  C  CG  . PHE B 1 163 ? -41.737 27.596  26.242  1.00 24.33  ? 142 PHE B CG  1 
ATOM   4265  C  CD1 . PHE B 1 163 ? -42.184 26.382  26.734  1.00 25.08  ? 142 PHE B CD1 1 
ATOM   4266  C  CD2 . PHE B 1 163 ? -40.429 27.702  25.816  1.00 25.52  ? 142 PHE B CD2 1 
ATOM   4267  C  CE1 . PHE B 1 163 ? -41.335 25.266  26.783  1.00 23.22  ? 142 PHE B CE1 1 
ATOM   4268  C  CE2 . PHE B 1 163 ? -39.561 26.587  25.869  1.00 26.20  ? 142 PHE B CE2 1 
ATOM   4269  C  CZ  . PHE B 1 163 ? -40.007 25.385  26.351  1.00 27.42  ? 142 PHE B CZ  1 
ATOM   4270  N  N   . GLU B 1 164 ? -40.911 30.574  27.941  1.00 22.89  ? 143 GLU B N   1 
ATOM   4271  C  CA  . GLU B 1 164 ? -39.625 30.785  28.613  1.00 25.28  ? 143 GLU B CA  1 
ATOM   4272  C  C   . GLU B 1 164 ? -39.812 31.228  30.063  1.00 24.87  ? 143 GLU B C   1 
ATOM   4273  O  O   . GLU B 1 164 ? -39.122 30.732  30.960  1.00 23.85  ? 143 GLU B O   1 
ATOM   4274  C  CB  . GLU B 1 164 ? -38.780 31.820  27.854  1.00 26.16  ? 143 GLU B CB  1 
ATOM   4275  C  CG  . GLU B 1 164 ? -38.388 31.393  26.440  1.00 42.09  ? 143 GLU B CG  1 
ATOM   4276  C  CD  . GLU B 1 164 ? -37.382 30.243  26.413  1.00 53.59  ? 143 GLU B CD  1 
ATOM   4277  O  OE1 . GLU B 1 164 ? -36.734 29.973  27.471  1.00 44.58  ? 143 GLU B OE1 1 
ATOM   4278  O  OE2 . GLU B 1 164 ? -37.256 29.607  25.328  1.00 42.24  ? 143 GLU B OE2 1 
ATOM   4279  N  N   . ASP B 1 165 ? -40.708 32.193  30.316  1.00 22.67  ? 144 ASP B N   1 
ATOM   4280  C  CA  . ASP B 1 165 ? -40.743 32.775  31.664  1.00 21.12  ? 144 ASP B CA  1 
ATOM   4281  C  C   . ASP B 1 165 ? -41.499 31.886  32.654  1.00 23.34  ? 144 ASP B C   1 
ATOM   4282  O  O   . ASP B 1 165 ? -41.118 31.801  33.827  1.00 24.48  ? 144 ASP B O   1 
ATOM   4283  C  CB  . ASP B 1 165 ? -41.357 34.180  31.627  1.00 22.70  ? 144 ASP B CB  1 
ATOM   4284  C  CG  . ASP B 1 165 ? -40.625 35.116  30.661  1.00 29.82  ? 144 ASP B CG  1 
ATOM   4285  O  OD1 . ASP B 1 165 ? -39.480 34.802  30.272  1.00 26.14  ? 144 ASP B OD1 1 
ATOM   4286  O  OD2 . ASP B 1 165 ? -41.210 36.147  30.267  1.00 27.04  ? 144 ASP B OD2 1 
ATOM   4287  N  N   . LEU B 1 166 ? -42.565 31.200  32.222  1.00 22.50  ? 145 LEU B N   1 
ATOM   4288  C  CA  . LEU B 1 166 ? -43.219 30.319  33.185  1.00 23.29  ? 145 LEU B CA  1 
ATOM   4289  C  C   . LEU B 1 166 ? -42.456 29.005  33.355  1.00 21.66  ? 145 LEU B C   1 
ATOM   4290  O  O   . LEU B 1 166 ? -42.492 28.428  34.443  1.00 22.44  ? 145 LEU B O   1 
ATOM   4291  C  CB  . LEU B 1 166 ? -44.687 30.052  32.812  1.00 19.40  ? 145 LEU B CB  1 
ATOM   4292  C  CG  . LEU B 1 166 ? -45.570 31.324  32.886  1.00 26.74  ? 145 LEU B CG  1 
ATOM   4293  C  CD1 . LEU B 1 166 ? -47.064 31.019  32.776  1.00 27.45  ? 145 LEU B CD1 1 
ATOM   4294  C  CD2 . LEU B 1 166 ? -45.311 32.117  34.169  1.00 25.71  ? 145 LEU B CD2 1 
ATOM   4295  N  N   . SER B 1 167 ? -41.746 28.523  32.320  1.00 19.07  ? 146 SER B N   1 
ATOM   4296  C  CA  . SER B 1 167 ? -40.857 27.383  32.540  1.00 20.62  ? 146 SER B CA  1 
ATOM   4297  C  C   . SER B 1 167 ? -39.805 27.724  33.593  1.00 25.84  ? 146 SER B C   1 
ATOM   4298  O  O   . SER B 1 167 ? -39.497 26.906  34.463  1.00 21.78  ? 146 SER B O   1 
ATOM   4299  C  CB  . SER B 1 167 ? -40.187 26.959  31.225  1.00 22.00  ? 146 SER B CB  1 
ATOM   4300  O  OG  . SER B 1 167 ? -41.131 26.450  30.281  1.00 24.77  ? 146 SER B OG  1 
ATOM   4301  N  N   . LEU B 1 168 ? -39.296 28.952  33.557  1.00 25.02  ? 147 LEU B N   1 
ATOM   4302  C  CA  . LEU B 1 168 ? -38.337 29.394  34.561  1.00 19.87  ? 147 LEU B CA  1 
ATOM   4303  C  C   . LEU B 1 168 ? -38.979 29.512  35.949  1.00 25.69  ? 147 LEU B C   1 
ATOM   4304  O  O   . LEU B 1 168 ? -38.396 29.043  36.938  1.00 22.74  ? 147 LEU B O   1 
ATOM   4305  C  CB  . LEU B 1 168 ? -37.714 30.706  34.108  1.00 22.15  ? 147 LEU B CB  1 
ATOM   4306  C  CG  . LEU B 1 168 ? -36.738 31.321  35.125  1.00 28.52  ? 147 LEU B CG  1 
ATOM   4307  C  CD1 . LEU B 1 168 ? -35.589 30.348  35.394  1.00 27.01  ? 147 LEU B CD1 1 
ATOM   4308  C  CD2 . LEU B 1 168 ? -36.198 32.629  34.535  1.00 31.26  ? 147 LEU B CD2 1 
ATOM   4309  N  N   . ALA B 1 169 ? -40.190 30.083  36.034  1.00 21.24  ? 148 ALA B N   1 
ATOM   4310  C  CA  . ALA B 1 169 ? -40.928 30.121  37.303  1.00 24.24  ? 148 ALA B CA  1 
ATOM   4311  C  C   . ALA B 1 169 ? -41.116 28.734  37.868  1.00 22.82  ? 148 ALA B C   1 
ATOM   4312  O  O   . ALA B 1 169 ? -40.923 28.513  39.068  1.00 24.74  ? 148 ALA B O   1 
ATOM   4313  C  CB  . ALA B 1 169 ? -42.307 30.778  37.144  1.00 22.60  ? 148 ALA B CB  1 
ATOM   4314  N  N   . PHE B 1 170 ? -41.493 27.769  37.012  1.00 20.59  ? 149 PHE B N   1 
ATOM   4315  C  CA  . PHE B 1 170 ? -41.763 26.423  37.510  1.00 22.50  ? 149 PHE B CA  1 
ATOM   4316  C  C   . PHE B 1 170 ? -40.487 25.781  38.059  1.00 19.35  ? 149 PHE B C   1 
ATOM   4317  O  O   . PHE B 1 170 ? -40.519 25.062  39.073  1.00 23.56  ? 149 PHE B O   1 
ATOM   4318  C  CB  . PHE B 1 170 ? -42.339 25.568  36.370  1.00 20.19  ? 149 PHE B CB  1 
ATOM   4319  C  CG  . PHE B 1 170 ? -43.751 25.972  35.910  1.00 24.58  ? 149 PHE B CG  1 
ATOM   4320  C  CD1 . PHE B 1 170 ? -44.606 26.726  36.724  1.00 21.48  ? 149 PHE B CD1 1 
ATOM   4321  C  CD2 . PHE B 1 170 ? -44.208 25.560  34.663  1.00 22.86  ? 149 PHE B CD2 1 
ATOM   4322  C  CE1 . PHE B 1 170 ? -45.881 27.061  36.311  1.00 21.97  ? 149 PHE B CE1 1 
ATOM   4323  C  CE2 . PHE B 1 170 ? -45.480 25.895  34.211  1.00 24.30  ? 149 PHE B CE2 1 
ATOM   4324  C  CZ  . PHE B 1 170 ? -46.340 26.648  35.047  1.00 22.22  ? 149 PHE B CZ  1 
ATOM   4325  N  N   . GLY B 1 171 ? -39.361 25.991  37.373  1.00 21.24  ? 150 GLY B N   1 
ATOM   4326  C  CA  . GLY B 1 171 ? -38.106 25.434  37.844  1.00 27.13  ? 150 GLY B CA  1 
ATOM   4327  C  C   . GLY B 1 171 ? -37.611 26.081  39.129  1.00 25.81  ? 150 GLY B C   1 
ATOM   4328  O  O   . GLY B 1 171 ? -37.077 25.399  40.005  1.00 25.59  ? 150 GLY B O   1 
ATOM   4329  N  N   . ARG B 1 172 ? -37.762 27.409  39.255  1.00 25.10  ? 151 ARG B N   1 
ATOM   4330  C  CA  . ARG B 1 172 ? -37.449 28.047  40.534  1.00 23.47  ? 151 ARG B CA  1 
ATOM   4331  C  C   . ARG B 1 172 ? -38.279 27.430  41.656  1.00 24.22  ? 151 ARG B C   1 
ATOM   4332  O  O   . ARG B 1 172 ? -37.746 27.108  42.721  1.00 27.19  ? 151 ARG B O   1 
ATOM   4333  C  CB  . ARG B 1 172 ? -37.695 29.558  40.451  1.00 22.76  ? 151 ARG B CB  1 
ATOM   4334  C  CG  . ARG B 1 172 ? -36.758 30.290  39.510  1.00 24.59  ? 151 ARG B CG  1 
ATOM   4335  C  CD  . ARG B 1 172 ? -37.225 31.740  39.373  1.00 30.57  ? 151 ARG B CD  1 
ATOM   4336  N  NE  . ARG B 1 172 ? -36.225 32.565  38.703  1.00 36.77  ? 151 ARG B NE  1 
ATOM   4337  C  CZ  . ARG B 1 172 ? -36.484 33.767  38.203  1.00 48.71  ? 151 ARG B CZ  1 
ATOM   4338  N  NH1 . ARG B 1 172 ? -37.690 34.301  38.282  1.00 46.15  ? 151 ARG B NH1 1 
ATOM   4339  N  NH2 . ARG B 1 172 ? -35.509 34.450  37.604  1.00 39.36  ? 151 ARG B NH2 1 
ATOM   4340  N  N   . ALA B 1 173 ? -39.584 27.212  41.411  1.00 21.65  ? 152 ALA B N   1 
ATOM   4341  C  CA  . ALA B 1 173 ? -40.452 26.624  42.440  1.00 24.08  ? 152 ALA B CA  1 
ATOM   4342  C  C   . ALA B 1 173 ? -40.033 25.196  42.771  1.00 24.62  ? 152 ALA B C   1 
ATOM   4343  O  O   . ALA B 1 173 ? -39.999 24.804  43.944  1.00 27.42  ? 152 ALA B O   1 
ATOM   4344  C  CB  . ALA B 1 173 ? -41.920 26.658  41.992  1.00 20.63  ? 152 ALA B CB  1 
ATOM   4345  N  N   . ALA B 1 174 ? -39.687 24.412  41.743  1.00 25.86  ? 153 ALA B N   1 
ATOM   4346  C  CA  . ALA B 1 174 ? -39.273 23.029  41.953  1.00 26.43  ? 153 ALA B CA  1 
ATOM   4347  C  C   . ALA B 1 174 ? -37.997 22.945  42.781  1.00 21.73  ? 153 ALA B C   1 
ATOM   4348  O  O   . ALA B 1 174 ? -37.894 22.104  43.673  1.00 24.58  ? 153 ALA B O   1 
ATOM   4349  C  CB  . ALA B 1 174 ? -39.044 22.340  40.611  1.00 24.18  ? 153 ALA B CB  1 
ATOM   4350  N  N   . PHE B 1 175 ? -37.009 23.798  42.475  1.00 24.22  ? 154 PHE B N   1 
ATOM   4351  C  CA  . PHE B 1 175 ? -35.753 23.777  43.221  1.00 24.72  ? 154 PHE B CA  1 
ATOM   4352  C  C   . PHE B 1 175 ? -35.993 24.130  44.689  1.00 28.92  ? 154 PHE B C   1 
ATOM   4353  O  O   . PHE B 1 175 ? -35.494 23.452  45.584  1.00 28.75  ? 154 PHE B O   1 
ATOM   4354  C  CB  . PHE B 1 175 ? -34.746 24.733  42.568  1.00 21.96  ? 154 PHE B CB  1 
ATOM   4355  C  CG  . PHE B 1 175 ? -33.933 24.116  41.468  1.00 33.74  ? 154 PHE B CG  1 
ATOM   4356  C  CD1 . PHE B 1 175 ? -34.529 23.315  40.482  1.00 29.85  ? 154 PHE B CD1 1 
ATOM   4357  C  CD2 . PHE B 1 175 ? -32.568 24.363  41.384  1.00 28.12  ? 154 PHE B CD2 1 
ATOM   4358  C  CE1 . PHE B 1 175 ? -33.767 22.760  39.457  1.00 32.02  ? 154 PHE B CE1 1 
ATOM   4359  C  CE2 . PHE B 1 175 ? -31.796 23.819  40.349  1.00 32.01  ? 154 PHE B CE2 1 
ATOM   4360  C  CZ  . PHE B 1 175 ? -32.393 23.002  39.392  1.00 35.45  ? 154 PHE B CZ  1 
ATOM   4361  N  N   . ARG B 1 176 ? -36.777 25.182  44.957  1.00 26.07  ? 155 ARG B N   1 
ATOM   4362  C  CA  . ARG B 1 176 ? -37.072 25.516  46.346  1.00 30.20  ? 155 ARG B CA  1 
ATOM   4363  C  C   . ARG B 1 176 ? -37.852 24.403  47.022  1.00 28.82  ? 155 ARG B C   1 
ATOM   4364  O  O   . ARG B 1 176 ? -37.582 24.056  48.177  1.00 25.39  ? 155 ARG B O   1 
ATOM   4365  C  CB  . ARG B 1 176 ? -37.858 26.820  46.414  1.00 27.91  ? 155 ARG B CB  1 
ATOM   4366  C  CG  . ARG B 1 176 ? -37.055 28.026  45.928  1.00 35.80  ? 155 ARG B CG  1 
ATOM   4367  C  CD  . ARG B 1 176 ? -37.936 29.297  45.866  1.00 49.07  ? 155 ARG B CD  1 
ATOM   4368  N  NE  . ARG B 1 176 ? -38.640 29.583  47.116  1.00 46.49  ? 155 ARG B NE  1 
ATOM   4369  C  CZ  . ARG B 1 176 ? -39.600 30.494  47.237  1.00 45.72  ? 155 ARG B CZ  1 
ATOM   4370  N  NH1 . ARG B 1 176 ? -40.017 31.200  46.199  1.00 48.53  ? 155 ARG B NH1 1 
ATOM   4371  N  NH2 . ARG B 1 176 ? -40.169 30.691  48.425  1.00 43.30  ? 155 ARG B NH2 1 
ATOM   4372  N  N   . TRP B 1 177 ? -38.836 23.829  46.315  1.00 24.40  ? 156 TRP B N   1 
ATOM   4373  C  CA  . TRP B 1 177 ? -39.635 22.750  46.891  1.00 23.98  ? 156 TRP B CA  1 
ATOM   4374  C  C   . TRP B 1 177 ? -38.763 21.555  47.242  1.00 27.15  ? 156 TRP B C   1 
ATOM   4375  O  O   . TRP B 1 177 ? -38.980 20.887  48.258  1.00 30.15  ? 156 TRP B O   1 
ATOM   4376  C  CB  . TRP B 1 177 ? -40.725 22.335  45.900  1.00 28.74  ? 156 TRP B CB  1 
ATOM   4377  C  CG  . TRP B 1 177 ? -41.445 21.081  46.242  1.00 24.98  ? 156 TRP B CG  1 
ATOM   4378  C  CD1 . TRP B 1 177 ? -42.462 20.930  47.152  1.00 26.22  ? 156 TRP B CD1 1 
ATOM   4379  C  CD2 . TRP B 1 177 ? -41.272 19.801  45.608  1.00 25.66  ? 156 TRP B CD2 1 
ATOM   4380  N  NE1 . TRP B 1 177 ? -42.909 19.618  47.148  1.00 25.64  ? 156 TRP B NE1 1 
ATOM   4381  C  CE2 . TRP B 1 177 ? -42.197 18.908  46.208  1.00 25.96  ? 156 TRP B CE2 1 
ATOM   4382  C  CE3 . TRP B 1 177 ? -40.419 19.326  44.599  1.00 25.89  ? 156 TRP B CE3 1 
ATOM   4383  C  CZ2 . TRP B 1 177 ? -42.277 17.560  45.849  1.00 25.17  ? 156 TRP B CZ2 1 
ATOM   4384  C  CZ3 . TRP B 1 177 ? -40.516 17.969  44.215  1.00 24.19  ? 156 TRP B CZ3 1 
ATOM   4385  C  CH2 . TRP B 1 177 ? -41.436 17.110  44.847  1.00 24.22  ? 156 TRP B CH2 1 
ATOM   4386  N  N   . ALA B 1 178 ? -37.819 21.226  46.374  1.00 25.75  ? 157 ALA B N   1 
ATOM   4387  C  CA  . ALA B 1 178 ? -37.000 20.049  46.581  1.00 23.94  ? 157 ALA B CA  1 
ATOM   4388  C  C   . ALA B 1 178 ? -35.920 20.262  47.628  1.00 29.73  ? 157 ALA B C   1 
ATOM   4389  O  O   . ALA B 1 178 ? -35.248 19.289  47.997  1.00 27.85  ? 157 ALA B O   1 
ATOM   4390  C  CB  . ALA B 1 178 ? -36.339 19.634  45.254  1.00 24.56  ? 157 ALA B CB  1 
ATOM   4391  N  N   . GLY B 1 179 ? -35.711 21.512  48.067  1.00 28.70  ? 158 GLY B N   1 
ATOM   4392  C  CA  . GLY B 1 179 ? -34.645 21.836  48.988  1.00 31.00  ? 158 GLY B CA  1 
ATOM   4393  C  C   . GLY B 1 179 ? -33.302 22.059  48.340  1.00 38.56  ? 158 GLY B C   1 
ATOM   4394  O  O   . GLY B 1 179 ? -32.273 21.915  49.011  1.00 35.73  ? 158 GLY B O   1 
ATOM   4395  N  N   . ILE B 1 180 ? -33.272 22.399  47.051  1.00 30.09  ? 159 ILE B N   1 
ATOM   4396  C  CA  . ILE B 1 180 ? -32.039 22.806  46.383  1.00 30.13  ? 159 ILE B CA  1 
ATOM   4397  C  C   . ILE B 1 180 ? -31.908 24.313  46.585  1.00 33.90  ? 159 ILE B C   1 
ATOM   4398  O  O   . ILE B 1 180 ? -32.600 25.096  45.938  1.00 39.98  ? 159 ILE B O   1 
ATOM   4399  C  CB  . ILE B 1 180 ? -32.032 22.450  44.896  1.00 36.55  ? 159 ILE B CB  1 
ATOM   4400  C  CG1 . ILE B 1 180 ? -32.331 20.974  44.668  1.00 29.17  ? 159 ILE B CG1 1 
ATOM   4401  C  CG2 . ILE B 1 180 ? -30.692 22.832  44.279  1.00 38.46  ? 159 ILE B CG2 1 
ATOM   4402  C  CD1 . ILE B 1 180 ? -32.580 20.584  43.173  1.00 26.74  ? 159 ILE B CD1 1 
ATOM   4403  N  N   . ASP B 1 181 ? -31.006 24.725  47.473  1.00 32.03  ? 160 ASP B N   1 
ATOM   4404  C  CA  . ASP B 1 181 ? -30.885 26.127  47.872  1.00 42.09  ? 160 ASP B CA  1 
ATOM   4405  C  C   . ASP B 1 181 ? -29.586 26.667  47.285  1.00 38.95  ? 160 ASP B C   1 
ATOM   4406  O  O   . ASP B 1 181 ? -28.499 26.409  47.807  1.00 43.09  ? 160 ASP B O   1 
ATOM   4407  C  CB  . ASP B 1 181 ? -30.928 26.257  49.395  1.00 38.30  ? 160 ASP B CB  1 
ATOM   4408  C  CG  . ASP B 1 181 ? -30.879 27.729  49.881  1.00 60.97  ? 160 ASP B CG  1 
ATOM   4409  O  OD1 . ASP B 1 181 ? -30.864 28.695  49.063  1.00 45.07  ? 160 ASP B OD1 1 
ATOM   4410  O  OD2 . ASP B 1 181 ? -30.857 27.912  51.115  1.00 57.24  ? 160 ASP B OD2 1 
ATOM   4411  N  N   . LEU B 1 182 ? -29.701 27.402  46.192  1.00 37.21  ? 161 LEU B N   1 
ATOM   4412  C  CA  . LEU B 1 182 ? -28.564 27.923  45.453  1.00 40.46  ? 161 LEU B CA  1 
ATOM   4413  C  C   . LEU B 1 182 ? -28.824 29.392  45.182  1.00 38.77  ? 161 LEU B C   1 
ATOM   4414  O  O   . LEU B 1 182 ? -29.978 29.827  45.141  1.00 39.16  ? 161 LEU B O   1 
ATOM   4415  C  CB  . LEU B 1 182 ? -28.355 27.174  44.123  1.00 39.65  ? 161 LEU B CB  1 
ATOM   4416  C  CG  . LEU B 1 182 ? -28.174 25.651  44.132  1.00 42.72  ? 161 LEU B CG  1 
ATOM   4417  C  CD1 . LEU B 1 182 ? -28.163 25.101  42.681  1.00 30.98  ? 161 LEU B CD1 1 
ATOM   4418  C  CD2 . LEU B 1 182 ? -26.905 25.244  44.879  1.00 46.88  ? 161 LEU B CD2 1 
ATOM   4419  N  N   . PRO B 1 183 ? -27.776 30.184  44.977  1.00 34.60  ? 162 PRO B N   1 
ATOM   4420  C  CA  . PRO B 1 183 ? -27.988 31.584  44.613  1.00 36.24  ? 162 PRO B CA  1 
ATOM   4421  C  C   . PRO B 1 183 ? -28.885 31.692  43.384  1.00 40.31  ? 162 PRO B C   1 
ATOM   4422  O  O   . PRO B 1 183 ? -28.934 30.789  42.544  1.00 42.19  ? 162 PRO B O   1 
ATOM   4423  C  CB  . PRO B 1 183 ? -26.572 32.093  44.336  1.00 38.00  ? 162 PRO B CB  1 
ATOM   4424  C  CG  . PRO B 1 183 ? -25.683 31.163  45.123  1.00 44.72  ? 162 PRO B CG  1 
ATOM   4425  C  CD  . PRO B 1 183 ? -26.349 29.827  45.054  1.00 40.83  ? 162 PRO B CD  1 
ATOM   4426  N  N   . ALA B 1 184 ? -29.627 32.796  43.305  1.00 36.28  ? 163 ALA B N   1 
ATOM   4427  C  CA  . ALA B 1 184 ? -30.641 32.935  42.263  1.00 35.33  ? 163 ALA B CA  1 
ATOM   4428  C  C   . ALA B 1 184 ? -30.040 32.833  40.862  1.00 46.87  ? 163 ALA B C   1 
ATOM   4429  O  O   . ALA B 1 184 ? -30.670 32.292  39.944  1.00 34.80  ? 163 ALA B O   1 
ATOM   4430  C  CB  . ALA B 1 184 ? -31.390 34.257  42.430  1.00 45.38  ? 163 ALA B CB  1 
ATOM   4431  N  N   . GLU B 1 185 ? -28.829 33.348  40.663  1.00 37.66  ? 164 GLU B N   1 
ATOM   4432  C  CA  . GLU B 1 185 ? -28.275 33.291  39.311  1.00 46.92  ? 164 GLU B CA  1 
ATOM   4433  C  C   . GLU B 1 185 ? -27.936 31.859  38.932  1.00 37.66  ? 164 GLU B C   1 
ATOM   4434  O  O   . GLU B 1 185 ? -28.149 31.443  37.787  1.00 33.29  ? 164 GLU B O   1 
ATOM   4435  C  CB  . GLU B 1 185 ? -27.045 34.188  39.195  1.00 46.52  ? 164 GLU B CB  1 
ATOM   4436  C  CG  . GLU B 1 185 ? -26.510 34.350  37.771  1.00 53.68  ? 164 GLU B CG  1 
ATOM   4437  C  CD  . GLU B 1 185 ? -25.411 35.407  37.673  1.00 77.26  ? 164 GLU B CD  1 
ATOM   4438  O  OE1 . GLU B 1 185 ? -25.722 36.614  37.810  1.00 75.17  ? 164 GLU B OE1 1 
ATOM   4439  O  OE2 . GLU B 1 185 ? -24.233 35.030  37.476  1.00 72.26  ? 164 GLU B OE2 1 
ATOM   4440  N  N   . ASN B 1 186 ? -27.429 31.092  39.893  1.00 31.99  ? 165 ASN B N   1 
ATOM   4441  C  CA  . ASN B 1 186 ? -27.090 29.696  39.670  1.00 30.61  ? 165 ASN B CA  1 
ATOM   4442  C  C   . ASN B 1 186 ? -28.331 28.844  39.406  1.00 35.13  ? 165 ASN B C   1 
ATOM   4443  O  O   . ASN B 1 186 ? -28.321 27.952  38.533  1.00 29.86  ? 165 ASN B O   1 
ATOM   4444  C  CB  . ASN B 1 186 ? -26.368 29.165  40.891  1.00 31.74  ? 165 ASN B CB  1 
ATOM   4445  C  CG  . ASN B 1 186 ? -25.408 28.071  40.547  1.00 48.42  ? 165 ASN B CG  1 
ATOM   4446  O  OD1 . ASN B 1 186 ? -25.500 27.459  39.475  1.00 53.16  ? 165 ASN B OD1 1 
ATOM   4447  N  ND2 . ASN B 1 186 ? -24.467 27.815  41.442  1.00 52.74  ? 165 ASN B ND2 1 
ATOM   4448  N  N   . THR B 1 187 ? -29.371 29.047  40.212  1.00 28.51  ? 166 THR B N   1 
ATOM   4449  C  CA  . THR B 1 187 ? -30.636 28.361  39.975  1.00 33.19  ? 166 THR B CA  1 
ATOM   4450  C  C   . THR B 1 187 ? -31.146 28.637  38.570  1.00 28.92  ? 166 THR B C   1 
ATOM   4451  O  O   . THR B 1 187 ? -31.530 27.707  37.849  1.00 28.85  ? 166 THR B O   1 
ATOM   4452  C  CB  . THR B 1 187 ? -31.668 28.782  41.021  1.00 41.87  ? 166 THR B CB  1 
ATOM   4453  O  OG1 . THR B 1 187 ? -31.250 28.287  42.299  1.00 40.53  ? 166 THR B OG1 1 
ATOM   4454  C  CG2 . THR B 1 187 ? -33.051 28.187  40.681  1.00 29.66  ? 166 THR B CG2 1 
ATOM   4455  N  N   . ASP B 1 188 ? -31.171 29.919  38.169  1.00 27.56  ? 167 ASP B N   1 
ATOM   4456  C  CA  . ASP B 1 188 ? -31.684 30.275  36.855  1.00 34.24  ? 167 ASP B CA  1 
ATOM   4457  C  C   . ASP B 1 188 ? -30.867 29.644  35.740  1.00 36.06  ? 167 ASP B C   1 
ATOM   4458  O  O   . ASP B 1 188 ? -31.431 29.226  34.722  1.00 29.77  ? 167 ASP B O   1 
ATOM   4459  C  CB  . ASP B 1 188 ? -31.714 31.785  36.679  1.00 31.31  ? 167 ASP B CB  1 
ATOM   4460  C  CG  . ASP B 1 188 ? -32.780 32.454  37.545  1.00 45.57  ? 167 ASP B CG  1 
ATOM   4461  O  OD1 . ASP B 1 188 ? -33.506 31.760  38.318  1.00 38.68  ? 167 ASP B OD1 1 
ATOM   4462  O  OD2 . ASP B 1 188 ? -32.900 33.686  37.424  1.00 42.64  ? 167 ASP B OD2 1 
ATOM   4463  N  N   . GLU B 1 189 ? -29.533 29.585  35.898  1.00 27.38  ? 168 GLU B N   1 
ATOM   4464  C  CA  . GLU B 1 189 ? -28.705 28.947  34.873  1.00 27.37  ? 168 GLU B CA  1 
ATOM   4465  C  C   . GLU B 1 189 ? -29.019 27.454  34.748  1.00 28.72  ? 168 GLU B C   1 
ATOM   4466  O  O   . GLU B 1 189 ? -29.117 26.927  33.630  1.00 29.86  ? 168 GLU B O   1 
ATOM   4467  C  CB  . GLU B 1 189 ? -27.218 29.158  35.184  1.00 32.10  ? 168 GLU B CB  1 
ATOM   4468  C  CG  . GLU B 1 189 ? -26.303 28.541  34.135  1.00 47.25  ? 168 GLU B CG  1 
ATOM   4469  C  CD  . GLU B 1 189 ? -25.056 27.912  34.739  1.00 70.76  ? 168 GLU B CD  1 
ATOM   4470  O  OE1 . GLU B 1 189 ? -24.086 28.657  35.001  1.00 73.38  ? 168 GLU B OE1 1 
ATOM   4471  O  OE2 . GLU B 1 189 ? -25.053 26.672  34.956  1.00 69.95  ? 168 GLU B OE2 1 
ATOM   4472  N  N   . LEU B 1 190 ? -29.178 26.752  35.878  1.00 24.60  ? 169 LEU B N   1 
ATOM   4473  C  CA  . LEU B 1 190 ? -29.478 25.321  35.830  1.00 30.80  ? 169 LEU B CA  1 
ATOM   4474  C  C   . LEU B 1 190 ? -30.880 25.057  35.275  1.00 28.81  ? 169 LEU B C   1 
ATOM   4475  O  O   . LEU B 1 190 ? -31.065 24.144  34.464  1.00 23.22  ? 169 LEU B O   1 
ATOM   4476  C  CB  . LEU B 1 190 ? -29.321 24.697  37.222  1.00 26.61  ? 169 LEU B CB  1 
ATOM   4477  C  CG  . LEU B 1 190 ? -27.859 24.542  37.696  1.00 30.48  ? 169 LEU B CG  1 
ATOM   4478  C  CD1 . LEU B 1 190 ? -27.829 24.296  39.198  1.00 32.20  ? 169 LEU B CD1 1 
ATOM   4479  C  CD2 . LEU B 1 190 ? -27.166 23.390  36.943  1.00 31.20  ? 169 LEU B CD2 1 
ATOM   4480  N  N   . VAL B 1 191 ? -31.878 25.844  35.689  1.00 23.87  ? 170 VAL B N   1 
ATOM   4481  C  CA  . VAL B 1 191 ? -33.208 25.697  35.092  1.00 24.48  ? 170 VAL B CA  1 
ATOM   4482  C  C   . VAL B 1 191 ? -33.151 26.008  33.607  1.00 29.86  ? 170 VAL B C   1 
ATOM   4483  O  O   . VAL B 1 191 ? -33.820 25.358  32.788  1.00 23.18  ? 170 VAL B O   1 
ATOM   4484  C  CB  . VAL B 1 191 ? -34.216 26.590  35.837  1.00 21.44  ? 170 VAL B CB  1 
ATOM   4485  C  CG1 . VAL B 1 191 ? -35.589 26.613  35.121  1.00 21.65  ? 170 VAL B CG1 1 
ATOM   4486  C  CG2 . VAL B 1 191 ? -34.388 26.043  37.275  1.00 23.95  ? 170 VAL B CG2 1 
ATOM   4487  N  N   . GLY B 1 192 ? -32.362 27.019  33.231  1.00 24.77  ? 171 GLY B N   1 
ATOM   4488  C  CA  . GLY B 1 192 ? -32.164 27.303  31.819  1.00 23.47  ? 171 GLY B CA  1 
ATOM   4489  C  C   . GLY B 1 192 ? -31.617 26.118  31.046  1.00 22.93  ? 171 GLY B C   1 
ATOM   4490  O  O   . GLY B 1 192 ? -32.013 25.883  29.891  1.00 27.76  ? 171 GLY B O   1 
ATOM   4491  N  N   . ARG B 1 193 ? -30.676 25.374  31.645  1.00 22.34  ? 172 ARG B N   1 
ATOM   4492  C  CA  . ARG B 1 193 ? -30.166 24.172  30.974  1.00 23.60  ? 172 ARG B CA  1 
ATOM   4493  C  C   . ARG B 1 193 ? -31.263 23.131  30.808  1.00 25.76  ? 172 ARG B C   1 
ATOM   4494  O  O   . ARG B 1 193 ? -31.312 22.429  29.792  1.00 25.05  ? 172 ARG B O   1 
ATOM   4495  C  CB  . ARG B 1 193 ? -29.001 23.533  31.749  1.00 27.01  ? 172 ARG B CB  1 
ATOM   4496  C  CG  . ARG B 1 193 ? -27.764 24.401  31.962  1.00 23.90  ? 172 ARG B CG  1 
ATOM   4497  C  CD  . ARG B 1 193 ? -26.607 23.493  32.389  1.00 26.47  ? 172 ARG B CD  1 
ATOM   4498  N  NE  . ARG B 1 193 ? -25.363 24.241  32.564  1.00 34.72  ? 172 ARG B NE  1 
ATOM   4499  C  CZ  . ARG B 1 193 ? -24.534 24.582  31.586  1.00 45.49  ? 172 ARG B CZ  1 
ATOM   4500  N  NH1 . ARG B 1 193 ? -24.776 24.257  30.318  1.00 32.86  ? 172 ARG B NH1 1 
ATOM   4501  N  NH2 . ARG B 1 193 ? -23.432 25.271  31.887  1.00 39.64  ? 172 ARG B NH2 1 
ATOM   4502  N  N   . MET B 1 194 ? -32.135 22.993  31.811  1.00 24.49  ? 173 MET B N   1 
ATOM   4503  C  CA  . MET B 1 194 ? -33.241 22.044  31.688  1.00 20.49  ? 173 MET B CA  1 
ATOM   4504  C  C   . MET B 1 194 ? -34.197 22.469  30.579  1.00 23.31  ? 173 MET B C   1 
ATOM   4505  O  O   . MET B 1 194 ? -34.671 21.623  29.808  1.00 24.95  ? 173 MET B O   1 
ATOM   4506  C  CB  . MET B 1 194 ? -33.996 21.918  33.019  1.00 23.65  ? 173 MET B CB  1 
ATOM   4507  C  CG  . MET B 1 194 ? -33.169 21.224  34.112  1.00 23.89  ? 173 MET B CG  1 
ATOM   4508  S  SD  . MET B 1 194 ? -34.098 21.211  35.651  1.00 26.65  ? 173 MET B SD  1 
ATOM   4509  C  CE  . MET B 1 194 ? -33.099 20.099  36.645  1.00 26.62  ? 173 MET B CE  1 
ATOM   4510  N  N   . ILE B 1 195 ? -34.488 23.774  30.486  1.00 21.78  ? 174 ILE B N   1 
ATOM   4511  C  CA  . ILE B 1 195 ? -35.351 24.273  29.413  1.00 23.48  ? 174 ILE B CA  1 
ATOM   4512  C  C   . ILE B 1 195 ? -34.718 23.980  28.063  1.00 24.51  ? 174 ILE B C   1 
ATOM   4513  O  O   . ILE B 1 195 ? -35.376 23.469  27.151  1.00 21.43  ? 174 ILE B O   1 
ATOM   4514  C  CB  . ILE B 1 195 ? -35.641 25.775  29.580  1.00 26.70  ? 174 ILE B CB  1 
ATOM   4515  C  CG1 . ILE B 1 195 ? -36.428 26.061  30.883  1.00 24.81  ? 174 ILE B CG1 1 
ATOM   4516  C  CG2 . ILE B 1 195 ? -36.393 26.271  28.375  1.00 25.03  ? 174 ILE B CG2 1 
ATOM   4517  C  CD1 . ILE B 1 195 ? -36.519 27.585  31.274  1.00 24.24  ? 174 ILE B CD1 1 
ATOM   4518  N  N   . THR B 1 196 ? -33.421 24.274  27.921  1.00 21.66  ? 175 THR B N   1 
ATOM   4519  C  CA  . THR B 1 196 ? -32.740 23.966  26.666  1.00 20.22  ? 175 THR B CA  1 
ATOM   4520  C  C   . THR B 1 196 ? -32.819 22.484  26.337  1.00 22.74  ? 175 THR B C   1 
ATOM   4521  O  O   . THR B 1 196 ? -33.061 22.107  25.184  1.00 25.35  ? 175 THR B O   1 
ATOM   4522  C  CB  . THR B 1 196 ? -31.281 24.408  26.755  1.00 24.77  ? 175 THR B CB  1 
ATOM   4523  O  OG1 . THR B 1 196 ? -31.261 25.830  26.942  1.00 24.98  ? 175 THR B OG1 1 
ATOM   4524  C  CG2 . THR B 1 196 ? -30.499 24.040  25.486  1.00 29.19  ? 175 THR B CG2 1 
ATOM   4525  N  N   . LEU B 1 197 ? -32.577 21.629  27.334  1.00 23.53  ? 176 LEU B N   1 
ATOM   4526  C  CA  . LEU B 1 197 ? -32.693 20.189  27.142  1.00 21.46  ? 176 LEU B CA  1 
ATOM   4527  C  C   . LEU B 1 197 ? -34.095 19.817  26.661  1.00 24.97  ? 176 LEU B C   1 
ATOM   4528  O  O   . LEU B 1 197 ? -34.256 19.121  25.651  1.00 20.79  ? 176 LEU B O   1 
ATOM   4529  C  CB  . LEU B 1 197 ? -32.351 19.464  28.457  1.00 20.13  ? 176 LEU B CB  1 
ATOM   4530  C  CG  . LEU B 1 197 ? -32.218 17.929  28.458  1.00 29.04  ? 176 LEU B CG  1 
ATOM   4531  C  CD1 . LEU B 1 197 ? -31.652 17.482  29.809  1.00 27.99  ? 176 LEU B CD1 1 
ATOM   4532  C  CD2 . LEU B 1 197 ? -33.526 17.204  28.230  1.00 31.58  ? 176 LEU B CD2 1 
ATOM   4533  N  N   . LEU B 1 198 ? -35.123 20.251  27.389  1.00 19.59  ? 177 LEU B N   1 
ATOM   4534  C  CA  . LEU B 1 198 ? -36.506 19.916  27.012  1.00 21.00  ? 177 LEU B CA  1 
ATOM   4535  C  C   . LEU B 1 198 ? -36.876 20.414  25.623  1.00 26.56  ? 177 LEU B C   1 
ATOM   4536  O  O   . LEU B 1 198 ? -37.716 19.792  24.935  1.00 22.04  ? 177 LEU B O   1 
ATOM   4537  C  CB  . LEU B 1 198 ? -37.476 20.515  28.041  1.00 20.11  ? 177 LEU B CB  1 
ATOM   4538  C  CG  . LEU B 1 198 ? -37.399 19.812  29.387  1.00 23.64  ? 177 LEU B CG  1 
ATOM   4539  C  CD1 . LEU B 1 198 ? -37.997 20.745  30.466  1.00 21.81  ? 177 LEU B CD1 1 
ATOM   4540  C  CD2 . LEU B 1 198 ? -38.196 18.528  29.291  1.00 21.63  ? 177 LEU B CD2 1 
ATOM   4541  N  N   . ASP B 1 199 ? -36.310 21.552  25.205  1.00 22.63  ? 178 ASP B N   1 
ATOM   4542  C  CA  . ASP B 1 199 ? -36.719 22.170  23.950  1.00 24.49  ? 178 ASP B CA  1 
ATOM   4543  C  C   . ASP B 1 199 ? -36.009 21.570  22.752  1.00 26.26  ? 178 ASP B C   1 
ATOM   4544  O  O   . ASP B 1 199 ? -36.272 21.996  21.625  1.00 25.23  ? 178 ASP B O   1 
ATOM   4545  C  CB  . ASP B 1 199 ? -36.436 23.677  24.011  1.00 27.61  ? 178 ASP B CB  1 
ATOM   4546  C  CG  . ASP B 1 199 ? -37.455 24.519  23.242  1.00 32.38  ? 178 ASP B CG  1 
ATOM   4547  O  OD1 . ASP B 1 199 ? -38.587 24.061  22.947  1.00 32.87  ? 178 ASP B OD1 1 
ATOM   4548  O  OD2 . ASP B 1 199 ? -37.092 25.661  22.946  1.00 32.99  ? 178 ASP B OD2 1 
ATOM   4549  N  N   . ASN B 1 200 ? -35.117 20.605  22.974  1.00 23.16  ? 179 ASN B N   1 
ATOM   4550  C  CA  . ASN B 1 200 ? -34.220 20.130  21.933  1.00 27.38  ? 179 ASN B CA  1 
ATOM   4551  C  C   . ASN B 1 200 ? -34.070 18.626  21.806  1.00 23.11  ? 179 ASN B C   1 
ATOM   4552  O  O   . ASN B 1 200 ? -33.603 18.197  20.749  1.00 27.65  ? 179 ASN B O   1 
ATOM   4553  C  CB  . ASN B 1 200 ? -32.820 20.752  22.109  1.00 23.21  ? 179 ASN B CB  1 
ATOM   4554  C  CG  . ASN B 1 200 ? -32.782 22.182  21.617  1.00 26.57  ? 179 ASN B CG  1 
ATOM   4555  O  OD1 . ASN B 1 200 ? -32.899 22.427  20.417  1.00 29.21  ? 179 ASN B OD1 1 
ATOM   4556  N  ND2 . ASN B 1 200 ? -32.643 23.142  22.544  1.00 25.77  ? 179 ASN B ND2 1 
ATOM   4557  N  N   . PHE B 1 201 ? -34.472 17.798  22.788  1.00 21.57  ? 180 PHE B N   1 
ATOM   4558  C  CA  . PHE B 1 201 ? -34.127 16.376  22.742  1.00 24.30  ? 180 PHE B CA  1 
ATOM   4559  C  C   . PHE B 1 201 ? -34.838 15.620  21.627  1.00 22.51  ? 180 PHE B C   1 
ATOM   4560  O  O   . PHE B 1 201 ? -34.411 14.503  21.274  1.00 24.79  ? 180 PHE B O   1 
ATOM   4561  C  CB  . PHE B 1 201 ? -34.484 15.687  24.038  1.00 21.84  ? 180 PHE B CB  1 
ATOM   4562  C  CG  . PHE B 1 201 ? -35.965 15.512  24.225  1.00 20.10  ? 180 PHE B CG  1 
ATOM   4563  C  CD1 . PHE B 1 201 ? -36.746 16.577  24.710  1.00 26.08  ? 180 PHE B CD1 1 
ATOM   4564  C  CD2 . PHE B 1 201 ? -36.587 14.316  23.896  1.00 25.56  ? 180 PHE B CD2 1 
ATOM   4565  C  CE1 . PHE B 1 201 ? -38.126 16.429  24.881  1.00 23.70  ? 180 PHE B CE1 1 
ATOM   4566  C  CE2 . PHE B 1 201 ? -37.978 14.164  24.059  1.00 25.31  ? 180 PHE B CE2 1 
ATOM   4567  C  CZ  . PHE B 1 201 ? -38.743 15.227  24.538  1.00 24.77  ? 180 PHE B CZ  1 
ATOM   4568  N  N   . GLY B 1 202 ? -35.932 16.149  21.111  1.00 25.72  ? 181 GLY B N   1 
ATOM   4569  C  CA  . GLY B 1 202 ? -36.705 15.378  20.152  1.00 27.43  ? 181 GLY B CA  1 
ATOM   4570  C  C   . GLY B 1 202 ? -36.455 15.614  18.669  1.00 31.52  ? 181 GLY B C   1 
ATOM   4571  O  O   . GLY B 1 202 ? -37.190 15.057  17.849  1.00 28.36  ? 181 GLY B O   1 
ATOM   4572  N  N   . THR B 1 203 ? -35.480 16.418  18.286  1.00 26.67  ? 182 THR B N   1 
ATOM   4573  C  CA  . THR B 1 203 ? -35.242 16.733  16.882  1.00 30.72  ? 182 THR B CA  1 
ATOM   4574  C  C   . THR B 1 203 ? -33.808 16.398  16.502  1.00 31.84  ? 182 THR B C   1 
ATOM   4575  O  O   . THR B 1 203 ? -32.935 16.285  17.355  1.00 27.80  ? 182 THR B O   1 
ATOM   4576  C  CB  . THR B 1 203 ? -35.456 18.205  16.569  1.00 30.07  ? 182 THR B CB  1 
ATOM   4577  O  OG1 . THR B 1 203 ? -34.468 18.966  17.280  1.00 31.74  ? 182 THR B OG1 1 
ATOM   4578  C  CG2 . THR B 1 203 ? -36.856 18.648  16.991  1.00 30.43  ? 182 THR B CG2 1 
ATOM   4579  N  N   . ALA B 1 204 ? -33.585 16.252  15.195  1.00 28.62  ? 183 ALA B N   1 
ATOM   4580  C  CA  . ALA B 1 204 ? -32.261 15.866  14.707  1.00 32.05  ? 183 ALA B CA  1 
ATOM   4581  C  C   . ALA B 1 204 ? -31.265 16.992  14.914  1.00 32.62  ? 183 ALA B C   1 
ATOM   4582  O  O   . ALA B 1 204 ? -30.117 16.743  15.286  1.00 30.98  ? 183 ALA B O   1 
ATOM   4583  C  CB  . ALA B 1 204 ? -32.333 15.468  13.226  1.00 36.16  ? 183 ALA B CB  1 
ATOM   4584  N  N   . THR B 1 205 ? -31.689 18.240  14.713  1.00 28.94  ? 184 THR B N   1 
ATOM   4585  C  CA  . THR B 1 205 ? -30.777 19.352  14.963  1.00 35.71  ? 184 THR B CA  1 
ATOM   4586  C  C   . THR B 1 205 ? -30.612 19.651  16.443  1.00 33.05  ? 184 THR B C   1 
ATOM   4587  O  O   . THR B 1 205 ? -29.582 20.198  16.844  1.00 30.23  ? 184 THR B O   1 
ATOM   4588  C  CB  . THR B 1 205 ? -31.262 20.612  14.250  1.00 45.46  ? 184 THR B CB  1 
ATOM   4589  O  OG1 . THR B 1 205 ? -32.571 20.957  14.732  1.00 43.97  ? 184 THR B OG1 1 
ATOM   4590  C  CG2 . THR B 1 205 ? -31.338 20.355  12.757  1.00 44.42  ? 184 THR B CG2 1 
ATOM   4591  N  N   . GLY B 1 206 ? -31.608 19.334  17.269  1.00 31.09  ? 185 GLY B N   1 
ATOM   4592  C  CA  . GLY B 1 206 ? -31.486 19.647  18.686  1.00 29.51  ? 185 GLY B CA  1 
ATOM   4593  C  C   . GLY B 1 206 ? -30.779 18.614  19.550  1.00 26.82  ? 185 GLY B C   1 
ATOM   4594  O  O   . GLY B 1 206 ? -30.234 18.979  20.587  1.00 25.61  ? 185 GLY B O   1 
ATOM   4595  N  N   . THR B 1 207 ? -30.734 17.344  19.137  1.00 24.19  ? 186 THR B N   1 
ATOM   4596  C  CA  . THR B 1 207 ? -30.235 16.310  20.042  1.00 29.29  ? 186 THR B CA  1 
ATOM   4597  C  C   . THR B 1 207 ? -28.792 16.558  20.510  1.00 33.62  ? 186 THR B C   1 
ATOM   4598  O  O   . THR B 1 207 ? -28.534 16.332  21.703  1.00 24.63  ? 186 THR B O   1 
ATOM   4599  C  CB  . THR B 1 207 ? -30.449 14.911  19.414  1.00 31.52  ? 186 THR B CB  1 
ATOM   4600  O  OG1 . THR B 1 207 ? -30.020 13.879  20.313  1.00 28.44  ? 186 THR B OG1 1 
ATOM   4601  C  CG2 . THR B 1 207 ? -29.739 14.734  18.075  1.00 28.60  ? 186 THR B CG2 1 
ATOM   4602  N  N   . PRO B 1 208 ? -27.848 17.096  19.710  1.00 30.32  ? 187 PRO B N   1 
ATOM   4603  C  CA  . PRO B 1 208 ? -26.523 17.420  20.315  1.00 32.10  ? 187 PRO B CA  1 
ATOM   4604  C  C   . PRO B 1 208 ? -26.606 18.429  21.453  1.00 24.33  ? 187 PRO B C   1 
ATOM   4605  O  O   . PRO B 1 208 ? -25.840 18.341  22.420  1.00 27.23  ? 187 PRO B O   1 
ATOM   4606  C  CB  . PRO B 1 208 ? -25.712 18.007  19.141  1.00 28.99  ? 187 PRO B CB  1 
ATOM   4607  C  CG  . PRO B 1 208 ? -26.426 17.586  17.908  1.00 36.64  ? 187 PRO B CG  1 
ATOM   4608  C  CD  . PRO B 1 208 ? -27.882 17.448  18.277  1.00 33.52  ? 187 PRO B CD  1 
ATOM   4609  N  N   . LYS B 1 209 ? -27.479 19.423  21.329  1.00 25.04  ? 188 LYS B N   1 
ATOM   4610  C  CA  . LYS B 1 209 ? -27.618 20.416  22.386  1.00 30.57  ? 188 LYS B CA  1 
ATOM   4611  C  C   . LYS B 1 209 ? -28.233 19.791  23.625  1.00 27.82  ? 188 LYS B C   1 
ATOM   4612  O  O   . LYS B 1 209 ? -27.825 20.095  24.755  1.00 25.52  ? 188 LYS B O   1 
ATOM   4613  C  CB  . LYS B 1 209 ? -28.480 21.590  21.913  1.00 28.83  ? 188 LYS B CB  1 
ATOM   4614  C  CG  . LYS B 1 209 ? -28.022 22.242  20.636  1.00 39.61  ? 188 LYS B CG  1 
ATOM   4615  C  CD  . LYS B 1 209 ? -29.035 23.279  20.144  1.00 47.30  ? 188 LYS B CD  1 
ATOM   4616  C  CE  . LYS B 1 209 ? -28.969 23.361  18.598  1.00 46.58  ? 188 LYS B CE  1 
ATOM   4617  N  NZ  . LYS B 1 209 ? -29.628 24.571  18.048  1.00 51.04  ? 188 LYS B NZ  1 
ATOM   4618  N  N   . ALA B 1 210 ? -29.228 18.917  23.439  1.00 27.33  ? 189 ALA B N   1 
ATOM   4619  C  CA  . ALA B 1 210 ? -29.812 18.240  24.590  1.00 26.12  ? 189 ALA B CA  1 
ATOM   4620  C  C   . ALA B 1 210 ? -28.775 17.389  25.317  1.00 26.09  ? 189 ALA B C   1 
ATOM   4621  O  O   . ALA B 1 210 ? -28.721 17.395  26.550  1.00 27.38  ? 189 ALA B O   1 
ATOM   4622  C  CB  . ALA B 1 210 ? -31.000 17.391  24.152  1.00 22.97  ? 189 ALA B CB  1 
ATOM   4623  N  N   . PHE B 1 211 ? -27.940 16.636  24.572  1.00 25.69  ? 190 PHE B N   1 
ATOM   4624  C  CA  . PHE B 1 211 ? -26.962 15.791  25.255  1.00 25.48  ? 190 PHE B CA  1 
ATOM   4625  C  C   . PHE B 1 211 ? -25.890 16.624  25.934  1.00 28.10  ? 190 PHE B C   1 
ATOM   4626  O  O   . PHE B 1 211 ? -25.407 16.240  27.007  1.00 26.91  ? 190 PHE B O   1 
ATOM   4627  C  CB  . PHE B 1 211 ? -26.335 14.771  24.290  1.00 28.46  ? 190 PHE B CB  1 
ATOM   4628  C  CG  . PHE B 1 211 ? -27.109 13.501  24.202  1.00 27.56  ? 190 PHE B CG  1 
ATOM   4629  C  CD1 . PHE B 1 211 ? -27.061 12.578  25.238  1.00 24.42  ? 190 PHE B CD1 1 
ATOM   4630  C  CD2 . PHE B 1 211 ? -27.922 13.241  23.097  1.00 24.99  ? 190 PHE B CD2 1 
ATOM   4631  C  CE1 . PHE B 1 211 ? -27.797 11.404  25.189  1.00 30.07  ? 190 PHE B CE1 1 
ATOM   4632  C  CE2 . PHE B 1 211 ? -28.676 12.062  23.045  1.00 26.54  ? 190 PHE B CE2 1 
ATOM   4633  C  CZ  . PHE B 1 211 ? -28.608 11.147  24.091  1.00 27.67  ? 190 PHE B CZ  1 
ATOM   4634  N  N   . TRP B 1 212 ? -25.534 17.772  25.352  1.00 28.30  ? 191 TRP B N   1 
ATOM   4635  C  CA  . TRP B 1 212 ? -24.582 18.651  26.019  1.00 30.54  ? 191 TRP B CA  1 
ATOM   4636  C  C   . TRP B 1 212 ? -25.142 19.116  27.361  1.00 29.42  ? 191 TRP B C   1 
ATOM   4637  O  O   . TRP B 1 212 ? -24.465 19.038  28.386  1.00 29.65  ? 191 TRP B O   1 
ATOM   4638  C  CB  . TRP B 1 212 ? -24.228 19.845  25.119  1.00 28.87  ? 191 TRP B CB  1 
ATOM   4639  C  CG  . TRP B 1 212 ? -23.361 20.859  25.847  1.00 38.18  ? 191 TRP B CG  1 
ATOM   4640  C  CD1 . TRP B 1 212 ? -23.770 22.022  26.449  1.00 39.16  ? 191 TRP B CD1 1 
ATOM   4641  C  CD2 . TRP B 1 212 ? -21.953 20.759  26.093  1.00 45.16  ? 191 TRP B CD2 1 
ATOM   4642  N  NE1 . TRP B 1 212 ? -22.697 22.650  27.048  1.00 41.36  ? 191 TRP B NE1 1 
ATOM   4643  C  CE2 . TRP B 1 212 ? -21.574 21.896  26.840  1.00 39.09  ? 191 TRP B CE2 1 
ATOM   4644  C  CE3 . TRP B 1 212 ? -20.979 19.822  25.754  1.00 42.28  ? 191 TRP B CE3 1 
ATOM   4645  C  CZ2 . TRP B 1 212 ? -20.260 22.120  27.238  1.00 53.86  ? 191 TRP B CZ2 1 
ATOM   4646  C  CZ3 . TRP B 1 212 ? -19.676 20.043  26.158  1.00 49.01  ? 191 TRP B CZ3 1 
ATOM   4647  C  CH2 . TRP B 1 212 ? -19.329 21.184  26.889  1.00 54.70  ? 191 TRP B CH2 1 
ATOM   4648  N  N   . GLN B 1 213 ? -26.406 19.575  27.384  1.00 26.76  ? 192 GLN B N   1 
ATOM   4649  C  CA  . GLN B 1 213 ? -26.995 20.010  28.651  1.00 22.12  ? 192 GLN B CA  1 
ATOM   4650  C  C   . GLN B 1 213 ? -27.133 18.854  29.620  1.00 24.91  ? 192 GLN B C   1 
ATOM   4651  O  O   . GLN B 1 213 ? -26.884 19.018  30.817  1.00 25.37  ? 192 GLN B O   1 
ATOM   4652  C  CB  . GLN B 1 213 ? -28.374 20.658  28.419  1.00 24.00  ? 192 GLN B CB  1 
ATOM   4653  C  CG  . GLN B 1 213 ? -28.326 21.852  27.490  1.00 28.01  ? 192 GLN B CG  1 
ATOM   4654  C  CD  . GLN B 1 213 ? -27.425 22.977  27.999  1.00 30.31  ? 192 GLN B CD  1 
ATOM   4655  O  OE1 . GLN B 1 213 ? -27.159 23.091  29.185  1.00 30.34  ? 192 GLN B OE1 1 
ATOM   4656  N  NE2 . GLN B 1 213 ? -26.929 23.792  27.078  1.00 33.36  ? 192 GLN B NE2 1 
ATOM   4657  N  N   . ARG B 1 214 ? -27.539 17.677  29.128  1.00 24.51  ? 193 ARG B N   1 
ATOM   4658  C  CA  . ARG B 1 214 ? -27.643 16.491  29.981  1.00 27.04  ? 193 ARG B CA  1 
ATOM   4659  C  C   . ARG B 1 214 ? -26.331 16.217  30.727  1.00 27.10  ? 193 ARG B C   1 
ATOM   4660  O  O   . ARG B 1 214 ? -26.327 15.949  31.938  1.00 26.83  ? 193 ARG B O   1 
ATOM   4661  C  CB  . ARG B 1 214 ? -28.048 15.280  29.128  1.00 25.93  ? 193 ARG B CB  1 
ATOM   4662  C  CG  . ARG B 1 214 ? -27.812 13.906  29.768  1.00 23.27  ? 193 ARG B CG  1 
ATOM   4663  C  CD  . ARG B 1 214 ? -28.567 13.693  31.082  1.00 29.75  ? 193 ARG B CD  1 
ATOM   4664  N  NE  . ARG B 1 214 ? -30.005 13.931  30.986  1.00 29.52  ? 193 ARG B NE  1 
ATOM   4665  C  CZ  . ARG B 1 214 ? -30.825 13.851  32.033  1.00 32.02  ? 193 ARG B CZ  1 
ATOM   4666  N  NH1 . ARG B 1 214 ? -30.382 13.507  33.238  1.00 29.50  ? 193 ARG B NH1 1 
ATOM   4667  N  NH2 . ARG B 1 214 ? -32.125 14.110  31.869  1.00 27.85  ? 193 ARG B NH2 1 
ATOM   4668  N  N   . ARG B 1 215 ? -25.212 16.278  30.005  1.00 27.97  ? 194 ARG B N   1 
ATOM   4669  C  CA  . ARG B 1 215 ? -23.907 16.045  30.613  1.00 25.71  ? 194 ARG B CA  1 
ATOM   4670  C  C   . ARG B 1 215 ? -23.615 17.086  31.698  1.00 26.74  ? 194 ARG B C   1 
ATOM   4671  O  O   . ARG B 1 215 ? -23.206 16.741  32.810  1.00 32.66  ? 194 ARG B O   1 
ATOM   4672  C  CB  . ARG B 1 215 ? -22.834 16.067  29.524  1.00 31.29  ? 194 ARG B CB  1 
ATOM   4673  C  CG  . ARG B 1 215 ? -21.403 15.995  30.071  1.00 40.66  ? 194 ARG B CG  1 
ATOM   4674  C  CD  . ARG B 1 215 ? -21.237 14.764  30.922  1.00 55.97  ? 194 ARG B CD  1 
ATOM   4675  N  NE  . ARG B 1 215 ? -21.619 13.565  30.187  1.00 70.14  ? 194 ARG B NE  1 
ATOM   4676  C  CZ  . ARG B 1 215 ? -20.763 12.781  29.547  1.00 70.67  ? 194 ARG B CZ  1 
ATOM   4677  N  NH1 . ARG B 1 215 ? -19.466 13.041  29.534  1.00 64.86  ? 194 ARG B NH1 1 
ATOM   4678  N  NH2 . ARG B 1 215 ? -21.220 11.704  28.911  1.00 79.27  ? 194 ARG B NH2 1 
ATOM   4679  N  N   . GLN B 1 216 ? -23.854 18.363  31.404  1.00 26.26  ? 195 GLN B N   1 
ATOM   4680  C  CA  . GLN B 1 216 ? -23.571 19.401  32.399  1.00 30.67  ? 195 GLN B CA  1 
ATOM   4681  C  C   . GLN B 1 216 ? -24.459 19.253  33.623  1.00 32.03  ? 195 GLN B C   1 
ATOM   4682  O  O   . GLN B 1 216 ? -23.985 19.381  34.755  1.00 27.91  ? 195 GLN B O   1 
ATOM   4683  C  CB  . GLN B 1 216 ? -23.729 20.788  31.793  1.00 26.66  ? 195 GLN B CB  1 
ATOM   4684  C  CG  . GLN B 1 216 ? -22.878 21.021  30.531  1.00 30.64  ? 195 GLN B CG  1 
ATOM   4685  C  CD  . GLN B 1 216 ? -21.438 20.605  30.719  1.00 44.51  ? 195 GLN B CD  1 
ATOM   4686  O  OE1 . GLN B 1 216 ? -20.789 21.028  31.666  1.00 46.48  ? 195 GLN B OE1 1 
ATOM   4687  N  NE2 . GLN B 1 216 ? -20.944 19.743  29.837  1.00 45.34  ? 195 GLN B NE2 1 
ATOM   4688  N  N   . LEU B 1 217 ? -25.753 18.965  33.411  1.00 27.33  ? 196 LEU B N   1 
ATOM   4689  C  CA  . LEU B 1 217 ? -26.690 18.765  34.514  1.00 24.45  ? 196 LEU B CA  1 
ATOM   4690  C  C   . LEU B 1 217 ? -26.337 17.528  35.345  1.00 24.77  ? 196 LEU B C   1 
ATOM   4691  O  O   . LEU B 1 217 ? -26.402 17.565  36.582  1.00 28.23  ? 196 LEU B O   1 
ATOM   4692  C  CB  . LEU B 1 217 ? -28.122 18.629  33.961  1.00 23.22  ? 196 LEU B CB  1 
ATOM   4693  C  CG  . LEU B 1 217 ? -28.730 19.960  33.517  1.00 28.57  ? 196 LEU B CG  1 
ATOM   4694  C  CD1 . LEU B 1 217 ? -29.989 19.721  32.683  1.00 25.05  ? 196 LEU B CD1 1 
ATOM   4695  C  CD2 . LEU B 1 217 ? -29.070 20.792  34.735  1.00 26.09  ? 196 LEU B CD2 1 
ATOM   4696  N  N   . ASP B 1 218 ? -25.999 16.416  34.693  1.00 26.56  ? 197 ASP B N   1 
ATOM   4697  C  CA  . ASP B 1 218 ? -25.630 15.209  35.442  1.00 25.54  ? 197 ASP B CA  1 
ATOM   4698  C  C   . ASP B 1 218 ? -24.391 15.443  36.309  1.00 26.33  ? 197 ASP B C   1 
ATOM   4699  O  O   . ASP B 1 218 ? -24.304 14.927  37.431  1.00 27.16  ? 197 ASP B O   1 
ATOM   4700  C  CB  . ASP B 1 218 ? -25.329 14.059  34.492  1.00 31.27  ? 197 ASP B CB  1 
ATOM   4701  C  CG  . ASP B 1 218 ? -26.569 13.430  33.879  1.00 34.22  ? 197 ASP B CG  1 
ATOM   4702  O  OD1 . ASP B 1 218 ? -27.701 13.839  34.231  1.00 35.23  ? 197 ASP B OD1 1 
ATOM   4703  O  OD2 . ASP B 1 218 ? -26.386 12.512  33.035  1.00 37.16  ? 197 ASP B OD2 1 
ATOM   4704  N  N   . ASN B 1 219 ? -23.382 16.119  35.754  1.00 27.00  ? 198 ASN B N   1 
ATOM   4705  C  CA  . ASN B 1 219 ? -22.203 16.488  36.542  1.00 26.91  ? 198 ASN B CA  1 
ATOM   4706  C  C   . ASN B 1 219 ? -22.605 17.338  37.738  1.00 30.57  ? 198 ASN B C   1 
ATOM   4707  O  O   . ASN B 1 219 ? -22.204 17.058  38.873  1.00 32.31  ? 198 ASN B O   1 
ATOM   4708  C  CB  . ASN B 1 219 ? -21.192 17.237  35.675  1.00 25.86  ? 198 ASN B CB  1 
ATOM   4709  C  CG  . ASN B 1 219 ? -20.564 16.355  34.604  1.00 33.73  ? 198 ASN B CG  1 
ATOM   4710  O  OD1 . ASN B 1 219 ? -20.657 15.133  34.662  1.00 35.54  ? 198 ASN B OD1 1 
ATOM   4711  N  ND2 . ASN B 1 219 ? -19.915 16.980  33.620  1.00 30.81  ? 198 ASN B ND2 1 
ATOM   4712  N  N   . TRP B 1 220 ? -23.431 18.368  37.504  1.00 33.01  ? 199 TRP B N   1 
ATOM   4713  C  CA  . TRP B 1 220 ? -23.864 19.235  38.596  1.00 29.50  ? 199 TRP B CA  1 
ATOM   4714  C  C   . TRP B 1 220 ? -24.570 18.445  39.685  1.00 29.37  ? 199 TRP B C   1 
ATOM   4715  O  O   . TRP B 1 220 ? -24.258 18.593  40.875  1.00 27.25  ? 199 TRP B O   1 
ATOM   4716  C  CB  . TRP B 1 220 ? -24.788 20.345  38.089  1.00 24.52  ? 199 TRP B CB  1 
ATOM   4717  C  CG  . TRP B 1 220 ? -25.626 20.900  39.222  1.00 34.03  ? 199 TRP B CG  1 
ATOM   4718  C  CD1 . TRP B 1 220 ? -25.197 21.734  40.224  1.00 33.12  ? 199 TRP B CD1 1 
ATOM   4719  C  CD2 . TRP B 1 220 ? -27.015 20.625  39.500  1.00 34.30  ? 199 TRP B CD2 1 
ATOM   4720  N  NE1 . TRP B 1 220 ? -26.221 21.987  41.099  1.00 30.11  ? 199 TRP B NE1 1 
ATOM   4721  C  CE2 . TRP B 1 220 ? -27.350 21.328  40.678  1.00 36.02  ? 199 TRP B CE2 1 
ATOM   4722  C  CE3 . TRP B 1 220 ? -28.007 19.873  38.858  1.00 37.29  ? 199 TRP B CE3 1 
ATOM   4723  C  CZ2 . TRP B 1 220 ? -28.650 21.317  41.223  1.00 33.32  ? 199 TRP B CZ2 1 
ATOM   4724  C  CZ3 . TRP B 1 220 ? -29.297 19.854  39.412  1.00 30.75  ? 199 TRP B CZ3 1 
ATOM   4725  C  CH2 . TRP B 1 220 ? -29.599 20.580  40.582  1.00 35.16  ? 199 TRP B CH2 1 
ATOM   4726  N  N   . ALA B 1 221 ? -25.550 17.608  39.299  1.00 26.24  ? 200 ALA B N   1 
ATOM   4727  C  CA  . ALA B 1 221 ? -26.337 16.865  40.278  1.00 27.49  ? 200 ALA B CA  1 
ATOM   4728  C  C   . ALA B 1 221 ? -25.494 15.830  41.012  1.00 27.85  ? 200 ALA B C   1 
ATOM   4729  O  O   . ALA B 1 221 ? -25.733 15.554  42.191  1.00 30.36  ? 200 ALA B O   1 
ATOM   4730  C  CB  . ALA B 1 221 ? -27.528 16.162  39.593  1.00 25.66  ? 200 ALA B CB  1 
ATOM   4731  N  N   . GLU B 1 222 ? -24.565 15.184  40.317  1.00 29.57  ? 201 GLU B N   1 
ATOM   4732  C  CA  . GLU B 1 222 ? -23.733 14.199  41.002  1.00 32.66  ? 201 GLU B CA  1 
ATOM   4733  C  C   . GLU B 1 222 ? -22.905 14.878  42.091  1.00 27.17  ? 201 GLU B C   1 
ATOM   4734  O  O   . GLU B 1 222 ? -22.834 14.389  43.218  1.00 35.24  ? 201 GLU B O   1 
ATOM   4735  C  CB  . GLU B 1 222 ? -22.827 13.471  40.011  1.00 31.86  ? 201 GLU B CB  1 
ATOM   4736  C  CG  . GLU B 1 222 ? -22.055 12.321  40.647  1.00 36.65  ? 201 GLU B CG  1 
ATOM   4737  C  CD  . GLU B 1 222 ? -21.001 11.730  39.732  1.00 38.08  ? 201 GLU B CD  1 
ATOM   4738  O  OE1 . GLU B 1 222 ? -21.084 11.926  38.509  1.00 42.99  ? 201 GLU B OE1 1 
ATOM   4739  O  OE2 . GLU B 1 222 ? -20.077 11.064  40.243  1.00 44.17  ? 201 GLU B OE2 1 
ATOM   4740  N  N   . ALA B 1 223 ? -22.333 16.042  41.782  1.00 30.35  ? 202 ALA B N   1 
ATOM   4741  C  CA  . ALA B 1 223 ? -21.539 16.752  42.779  1.00 34.92  ? 202 ALA B CA  1 
ATOM   4742  C  C   . ALA B 1 223 ? -22.408 17.238  43.932  1.00 37.91  ? 202 ALA B C   1 
ATOM   4743  O  O   . ALA B 1 223 ? -21.963 17.237  45.084  1.00 33.72  ? 202 ALA B O   1 
ATOM   4744  C  CB  . ALA B 1 223 ? -20.798 17.912  42.119  1.00 26.80  ? 202 ALA B CB  1 
ATOM   4745  N  N   . LEU B 1 224 ? -23.663 17.609  43.658  1.00 32.30  ? 203 LEU B N   1 
ATOM   4746  C  CA  . LEU B 1 224 ? -24.563 18.002  44.741  1.00 28.47  ? 203 LEU B CA  1 
ATOM   4747  C  C   . LEU B 1 224 ? -24.868 16.827  45.658  1.00 33.79  ? 203 LEU B C   1 
ATOM   4748  O  O   . LEU B 1 224 ? -24.800 16.960  46.887  1.00 36.67  ? 203 LEU B O   1 
ATOM   4749  C  CB  . LEU B 1 224 ? -25.860 18.594  44.170  1.00 29.17  ? 203 LEU B CB  1 
ATOM   4750  C  CG  . LEU B 1 224 ? -26.896 19.127  45.157  1.00 34.71  ? 203 LEU B CG  1 
ATOM   4751  C  CD1 . LEU B 1 224 ? -26.285 20.146  46.091  1.00 38.32  ? 203 LEU B CD1 1 
ATOM   4752  C  CD2 . LEU B 1 224 ? -28.068 19.747  44.419  1.00 33.98  ? 203 LEU B CD2 1 
ATOM   4753  N  N   . ILE B 1 225 ? -25.232 15.672  45.080  1.00 28.57  ? 204 ILE B N   1 
ATOM   4754  C  CA  . ILE B 1 225 ? -25.549 14.491  45.874  1.00 30.99  ? 204 ILE B CA  1 
ATOM   4755  C  C   . ILE B 1 225 ? -24.346 14.105  46.734  1.00 44.54  ? 204 ILE B C   1 
ATOM   4756  O  O   . ILE B 1 225 ? -24.474 13.821  47.932  1.00 34.56  ? 204 ILE B O   1 
ATOM   4757  C  CB  . ILE B 1 225 ? -25.982 13.320  44.965  1.00 32.01  ? 204 ILE B CB  1 
ATOM   4758  C  CG1 . ILE B 1 225 ? -27.383 13.551  44.377  1.00 27.70  ? 204 ILE B CG1 1 
ATOM   4759  C  CG2 . ILE B 1 225 ? -25.997 11.988  45.741  1.00 25.50  ? 204 ILE B CG2 1 
ATOM   4760  C  CD1 . ILE B 1 225 ? -28.520 13.582  45.417  1.00 28.99  ? 204 ILE B CD1 1 
ATOM   4761  N  N   . THR B 1 226 ? -23.162 14.085  46.118  1.00 35.50  ? 205 THR B N   1 
ATOM   4762  C  CA  . THR B 1 226 ? -21.937 13.740  46.832  1.00 38.29  ? 205 THR B CA  1 
ATOM   4763  C  C   . THR B 1 226 ? -21.657 14.713  47.975  1.00 38.16  ? 205 THR B C   1 
ATOM   4764  O  O   . THR B 1 226 ? -21.321 14.288  49.087  1.00 45.39  ? 205 THR B O   1 
ATOM   4765  C  CB  . THR B 1 226 ? -20.783 13.709  45.837  1.00 38.80  ? 205 THR B CB  1 
ATOM   4766  O  OG1 . THR B 1 226 ? -20.976 12.591  44.951  1.00 41.49  ? 205 THR B OG1 1 
ATOM   4767  C  CG2 . THR B 1 226 ? -19.437 13.580  46.555  1.00 41.13  ? 205 THR B CG2 1 
ATOM   4768  N  N   . ASP B 1 227 ? -21.814 16.016  47.728  1.00 34.59  ? 206 ASP B N   1 
ATOM   4769  C  CA  . ASP B 1 227 ? -21.624 17.004  48.790  1.00 36.51  ? 206 ASP B CA  1 
ATOM   4770  C  C   . ASP B 1 227 ? -22.567 16.757  49.955  1.00 50.31  ? 206 ASP B C   1 
ATOM   4771  O  O   . ASP B 1 227 ? -22.167 16.862  51.125  1.00 46.25  ? 206 ASP B O   1 
ATOM   4772  C  CB  . ASP B 1 227 ? -21.816 18.419  48.257  1.00 38.90  ? 206 ASP B CB  1 
ATOM   4773  C  CG  . ASP B 1 227 ? -20.653 18.895  47.416  1.00 47.40  ? 206 ASP B CG  1 
ATOM   4774  O  OD1 . ASP B 1 227 ? -19.534 18.386  47.598  1.00 63.96  ? 206 ASP B OD1 1 
ATOM   4775  O  OD2 . ASP B 1 227 ? -20.857 19.785  46.566  1.00 56.72  ? 206 ASP B OD2 1 
ATOM   4776  N  N   . VAL B 1 228 ? -23.827 16.441  49.662  1.00 39.12  ? 207 VAL B N   1 
ATOM   4777  C  CA  . VAL B 1 228 ? -24.764 16.114  50.729  1.00 36.62  ? 207 VAL B CA  1 
ATOM   4778  C  C   . VAL B 1 228 ? -24.311 14.865  51.471  1.00 36.95  ? 207 VAL B C   1 
ATOM   4779  O  O   . VAL B 1 228 ? -24.317 14.818  52.709  1.00 41.38  ? 207 VAL B O   1 
ATOM   4780  C  CB  . VAL B 1 228 ? -26.182 15.946  50.165  1.00 38.83  ? 207 VAL B CB  1 
ATOM   4781  C  CG1 . VAL B 1 228 ? -27.122 15.430  51.246  1.00 32.74  ? 207 VAL B CG1 1 
ATOM   4782  C  CG2 . VAL B 1 228 ? -26.675 17.281  49.618  1.00 36.44  ? 207 VAL B CG2 1 
ATOM   4783  N  N   . ARG B 1 229 ? -23.913 13.832  50.725  1.00 33.86  ? 208 ARG B N   1 
ATOM   4784  C  CA  . ARG B 1 229 ? -23.558 12.569  51.358  1.00 37.67  ? 208 ARG B CA  1 
ATOM   4785  C  C   . ARG B 1 229 ? -22.309 12.705  52.222  1.00 42.53  ? 208 ARG B C   1 
ATOM   4786  O  O   . ARG B 1 229 ? -22.147 11.954  53.187  1.00 42.39  ? 208 ARG B O   1 
ATOM   4787  C  CB  . ARG B 1 229 ? -23.352 11.492  50.298  1.00 40.22  ? 208 ARG B CB  1 
ATOM   4788  C  CG  . ARG B 1 229 ? -24.667 10.899  49.801  1.00 33.63  ? 208 ARG B CG  1 
ATOM   4789  C  CD  . ARG B 1 229 ? -24.411 9.961   48.664  1.00 36.96  ? 208 ARG B CD  1 
ATOM   4790  N  NE  . ARG B 1 229 ? -25.649 9.325   48.253  1.00 34.17  ? 208 ARG B NE  1 
ATOM   4791  C  CZ  . ARG B 1 229 ? -25.733 8.439   47.273  1.00 40.57  ? 208 ARG B CZ  1 
ATOM   4792  N  NH1 . ARG B 1 229 ? -24.672 8.109   46.549  1.00 32.82  ? 208 ARG B NH1 1 
ATOM   4793  N  NH2 . ARG B 1 229 ? -26.910 7.864   47.019  1.00 35.16  ? 208 ARG B NH2 1 
ATOM   4794  N  N   . GLU B 1 230 ? -21.432 13.654  51.891  1.00 41.22  ? 209 GLU B N   1 
ATOM   4795  C  CA  . GLU B 1 230 ? -20.174 13.866  52.596  1.00 40.46  ? 209 GLU B CA  1 
ATOM   4796  C  C   . GLU B 1 230 ? -20.247 14.987  53.621  1.00 50.04  ? 209 GLU B C   1 
ATOM   4797  O  O   . GLU B 1 230 ? -19.233 15.299  54.251  1.00 56.29  ? 209 GLU B O   1 
ATOM   4798  C  CB  . GLU B 1 230 ? -19.066 14.134  51.581  1.00 43.11  ? 209 GLU B CB  1 
ATOM   4799  C  CG  . GLU B 1 230 ? -18.751 12.888  50.779  1.00 47.70  ? 209 GLU B CG  1 
ATOM   4800  C  CD  . GLU B 1 230 ? -17.609 13.057  49.805  1.00 65.43  ? 209 GLU B CD  1 
ATOM   4801  O  OE1 . GLU B 1 230 ? -17.152 14.201  49.611  1.00 71.51  ? 209 GLU B OE1 1 
ATOM   4802  O  OE2 . GLU B 1 230 ? -17.171 12.036  49.226  1.00 69.31  ? 209 GLU B OE2 1 
ATOM   4803  N  N   . GLY B 1 231 ? -21.422 15.583  53.812  1.00 44.84  ? 210 GLY B N   1 
ATOM   4804  C  CA  . GLY B 1 231 ? -21.638 16.613  54.800  1.00 40.34  ? 210 GLY B CA  1 
ATOM   4805  C  C   . GLY B 1 231 ? -21.214 18.007  54.401  1.00 46.76  ? 210 GLY B C   1 
ATOM   4806  O  O   . GLY B 1 231 ? -21.454 18.942  55.171  1.00 55.73  ? 210 GLY B O   1 
ATOM   4807  N  N   . ARG B 1 232 ? -20.615 18.193  53.222  1.00 44.46  ? 211 ARG B N   1 
ATOM   4808  C  CA  . ARG B 1 232 ? -20.208 19.536  52.816  1.00 38.43  ? 211 ARG B CA  1 
ATOM   4809  C  C   . ARG B 1 232 ? -21.388 20.461  52.561  1.00 49.80  ? 211 ARG B C   1 
ATOM   4810  O  O   . ARG B 1 232 ? -21.224 21.683  52.614  1.00 53.48  ? 211 ARG B O   1 
ATOM   4811  C  CB  . ARG B 1 232 ? -19.335 19.468  51.576  1.00 43.95  ? 211 ARG B CB  1 
ATOM   4812  C  CG  . ARG B 1 232 ? -17.974 18.881  51.856  1.00 55.08  ? 211 ARG B CG  1 
ATOM   4813  C  CD  . ARG B 1 232 ? -17.029 19.124  50.696  1.00 63.22  ? 211 ARG B CD  1 
ATOM   4814  N  NE  . ARG B 1 232 ? -17.416 18.332  49.539  1.00 64.00  ? 211 ARG B NE  1 
ATOM   4815  C  CZ  . ARG B 1 232 ? -17.138 17.044  49.400  1.00 66.35  ? 211 ARG B CZ  1 
ATOM   4816  N  NH1 . ARG B 1 232 ? -16.451 16.385  50.319  1.00 61.82  ? 211 ARG B NH1 1 
ATOM   4817  N  NH2 . ARG B 1 232 ? -17.567 16.397  48.317  1.00 59.96  ? 211 ARG B NH2 1 
ATOM   4818  N  N   . ILE B 1 233 ? -22.562 19.913  52.276  1.00 43.10  ? 212 ILE B N   1 
ATOM   4819  C  CA  . ILE B 1 233 ? -23.788 20.684  52.128  1.00 48.11  ? 212 ILE B CA  1 
ATOM   4820  C  C   . ILE B 1 233 ? -24.831 20.047  53.030  1.00 44.29  ? 212 ILE B C   1 
ATOM   4821  O  O   . ILE B 1 233 ? -24.882 18.819  53.163  1.00 49.71  ? 212 ILE B O   1 
ATOM   4822  C  CB  . ILE B 1 233 ? -24.254 20.720  50.654  1.00 50.60  ? 212 ILE B CB  1 
ATOM   4823  C  CG1 . ILE B 1 233 ? -23.360 21.662  49.851  1.00 52.04  ? 212 ILE B CG1 1 
ATOM   4824  C  CG2 . ILE B 1 233 ? -25.714 21.150  50.526  1.00 48.29  ? 212 ILE B CG2 1 
ATOM   4825  C  CD1 . ILE B 1 233 ? -23.484 21.478  48.356  1.00 56.59  ? 212 ILE B CD1 1 
ATOM   4826  N  N   . THR B 1 234 ? -25.636 20.872  53.679  1.00 45.02  ? 213 THR B N   1 
ATOM   4827  C  CA  . THR B 1 234 ? -26.656 20.384  54.594  1.00 48.12  ? 213 THR B CA  1 
ATOM   4828  C  C   . THR B 1 234 ? -28.014 20.542  53.934  1.00 44.32  ? 213 THR B C   1 
ATOM   4829  O  O   . THR B 1 234 ? -28.429 21.663  53.629  1.00 57.58  ? 213 THR B O   1 
ATOM   4830  C  CB  . THR B 1 234 ? -26.618 21.141  55.919  1.00 49.02  ? 213 THR B CB  1 
ATOM   4831  O  OG1 . THR B 1 234 ? -25.361 20.905  56.563  1.00 61.39  ? 213 THR B OG1 1 
ATOM   4832  C  CG2 . THR B 1 234 ? -27.732 20.667  56.816  1.00 52.15  ? 213 THR B CG2 1 
ATOM   4833  N  N   . ALA B 1 235 ? -28.701 19.429  53.721  1.00 47.11  ? 214 ALA B N   1 
ATOM   4834  C  CA  . ALA B 1 235 ? -30.050 19.468  53.178  1.00 46.04  ? 214 ALA B CA  1 
ATOM   4835  C  C   . ALA B 1 235 ? -31.040 19.576  54.318  1.00 46.95  ? 214 ALA B C   1 
ATOM   4836  O  O   . ALA B 1 235 ? -30.831 19.001  55.390  1.00 44.26  ? 214 ALA B O   1 
ATOM   4837  C  CB  . ALA B 1 235 ? -30.354 18.220  52.340  1.00 46.44  ? 214 ALA B CB  1 
ATOM   4838  N  N   . ARG B 1 236 ? -32.104 20.334  54.085  1.00 41.63  ? 215 ARG B N   1 
ATOM   4839  C  CA  . ARG B 1 236 ? -33.192 20.407  55.041  1.00 43.76  ? 215 ARG B CA  1 
ATOM   4840  C  C   . ARG B 1 236 ? -33.670 18.994  55.360  1.00 54.57  ? 215 ARG B C   1 
ATOM   4841  O  O   . ARG B 1 236 ? -33.826 18.177  54.438  1.00 48.52  ? 215 ARG B O   1 
ATOM   4842  C  CB  . ARG B 1 236 ? -34.351 21.237  54.483  1.00 50.26  ? 215 ARG B CB  1 
ATOM   4843  C  CG  . ARG B 1 236 ? -35.351 21.676  55.536  1.00 53.90  ? 215 ARG B CG  1 
ATOM   4844  C  CD  . ARG B 1 236 ? -36.758 21.883  54.971  1.00 63.32  ? 215 ARG B CD  1 
ATOM   4845  N  NE  . ARG B 1 236 ? -36.757 22.382  53.599  1.00 68.10  ? 215 ARG B NE  1 
ATOM   4846  C  CZ  . ARG B 1 236 ? -37.523 21.898  52.628  1.00 64.08  ? 215 ARG B CZ  1 
ATOM   4847  N  NH1 . ARG B 1 236 ? -38.369 20.901  52.847  1.00 53.32  ? 215 ARG B NH1 1 
ATOM   4848  N  NH2 . ARG B 1 236 ? -37.456 22.443  51.412  1.00 53.28  ? 215 ARG B NH2 1 
ATOM   4849  N  N   . PRO B 1 237 ? -33.865 18.650  56.631  1.00 45.31  ? 216 PRO B N   1 
ATOM   4850  C  CA  . PRO B 1 237 ? -34.323 17.295  56.951  1.00 44.81  ? 216 PRO B CA  1 
ATOM   4851  C  C   . PRO B 1 237 ? -35.673 17.017  56.303  1.00 47.31  ? 216 PRO B C   1 
ATOM   4852  O  O   . PRO B 1 237 ? -36.540 17.891  56.231  1.00 43.52  ? 216 PRO B O   1 
ATOM   4853  C  CB  . PRO B 1 237 ? -34.411 17.299  58.482  1.00 47.03  ? 216 PRO B CB  1 
ATOM   4854  C  CG  . PRO B 1 237 ? -33.482 18.362  58.905  1.00 48.17  ? 216 PRO B CG  1 
ATOM   4855  C  CD  . PRO B 1 237 ? -33.580 19.432  57.843  1.00 54.17  ? 216 PRO B CD  1 
ATOM   4856  N  N   . ASP B 1 238 ? -35.817 15.794  55.792  1.00 40.38  ? 217 ASP B N   1 
ATOM   4857  C  CA  . ASP B 1 238 ? -37.020 15.267  55.145  1.00 40.69  ? 217 ASP B CA  1 
ATOM   4858  C  C   . ASP B 1 238 ? -37.335 15.913  53.793  1.00 39.67  ? 217 ASP B C   1 
ATOM   4859  O  O   . ASP B 1 238 ? -38.441 15.694  53.263  1.00 35.31  ? 217 ASP B O   1 
ATOM   4860  C  CB  . ASP B 1 238 ? -38.247 15.387  56.062  1.00 36.51  ? 217 ASP B CB  1 
ATOM   4861  C  CG  . ASP B 1 238 ? -39.335 14.371  55.725  1.00 43.14  ? 217 ASP B CG  1 
ATOM   4862  O  OD1 . ASP B 1 238 ? -39.004 13.251  55.268  1.00 42.19  ? 217 ASP B OD1 1 
ATOM   4863  O  OD2 . ASP B 1 238 ? -40.523 14.697  55.898  1.00 42.84  ? 217 ASP B OD2 1 
ATOM   4864  N  N   . CYS B 1 239 ? -36.420 16.699  53.213  1.00 31.17  ? 218 CYS B N   1 
ATOM   4865  C  CA  . CYS B 1 239 ? -36.685 17.297  51.910  1.00 31.57  ? 218 CYS B CA  1 
ATOM   4866  C  C   . CYS B 1 239 ? -36.321 16.315  50.792  1.00 36.87  ? 218 CYS B C   1 
ATOM   4867  O  O   . CYS B 1 239 ? -35.711 15.267  51.034  1.00 33.05  ? 218 CYS B O   1 
ATOM   4868  C  CB  . CYS B 1 239 ? -35.926 18.605  51.733  1.00 29.36  ? 218 CYS B CB  1 
ATOM   4869  S  SG  . CYS B 1 239 ? -34.153 18.499  51.411  1.00 35.62  ? 218 CYS B SG  1 
ATOM   4870  N  N   . VAL B 1 240 ? -36.733 16.659  49.560  1.00 29.62  ? 219 VAL B N   1 
ATOM   4871  C  CA  . VAL B 1 240 ? -36.498 15.786  48.398  1.00 32.21  ? 219 VAL B CA  1 
ATOM   4872  C  C   . VAL B 1 240 ? -35.006 15.536  48.196  1.00 29.78  ? 219 VAL B C   1 
ATOM   4873  O  O   . VAL B 1 240 ? -34.576 14.398  47.985  1.00 28.31  ? 219 VAL B O   1 
ATOM   4874  C  CB  . VAL B 1 240 ? -37.128 16.398  47.131  1.00 27.50  ? 219 VAL B CB  1 
ATOM   4875  C  CG1 . VAL B 1 240 ? -36.623 15.681  45.878  1.00 26.66  ? 219 VAL B CG1 1 
ATOM   4876  C  CG2 . VAL B 1 240 ? -38.632 16.394  47.238  1.00 27.89  ? 219 VAL B CG2 1 
ATOM   4877  N  N   . LEU B 1 241 ? -34.195 16.602  48.238  1.00 29.79  ? 220 LEU B N   1 
ATOM   4878  C  CA  . LEU B 1 241 ? -32.754 16.449  48.068  1.00 29.66  ? 220 LEU B CA  1 
ATOM   4879  C  C   . LEU B 1 241 ? -32.177 15.433  49.065  1.00 31.51  ? 220 LEU B C   1 
ATOM   4880  O  O   . LEU B 1 241 ? -31.344 14.598  48.695  1.00 32.44  ? 220 LEU B O   1 
ATOM   4881  C  CB  . LEU B 1 241 ? -32.064 17.812  48.203  1.00 27.95  ? 220 LEU B CB  1 
ATOM   4882  C  CG  . LEU B 1 241 ? -30.524 17.790  48.149  1.00 31.96  ? 220 LEU B CG  1 
ATOM   4883  C  CD1 . LEU B 1 241 ? -30.002 17.198  46.868  1.00 35.36  ? 220 LEU B CD1 1 
ATOM   4884  C  CD2 . LEU B 1 241 ? -29.970 19.197  48.317  1.00 30.49  ? 220 LEU B CD2 1 
ATOM   4885  N  N   . GLU B 1 242 ? -32.638 15.465  50.322  1.00 29.28  ? 221 GLU B N   1 
ATOM   4886  C  CA  . GLU B 1 242 ? -32.138 14.516  51.319  1.00 30.48  ? 221 GLU B CA  1 
ATOM   4887  C  C   . GLU B 1 242 ? -32.547 13.091  50.982  1.00 31.15  ? 221 GLU B C   1 
ATOM   4888  O  O   . GLU B 1 242 ? -31.750 12.152  51.116  1.00 30.85  ? 221 GLU B O   1 
ATOM   4889  C  CB  . GLU B 1 242 ? -32.647 14.879  52.724  1.00 31.90  ? 221 GLU B CB  1 
ATOM   4890  C  CG  . GLU B 1 242 ? -32.198 13.869  53.782  1.00 39.86  ? 221 GLU B CG  1 
ATOM   4891  C  CD  . GLU B 1 242 ? -32.841 14.087  55.152  1.00 61.28  ? 221 GLU B CD  1 
ATOM   4892  O  OE1 . GLU B 1 242 ? -34.043 13.765  55.317  1.00 56.29  ? 221 GLU B OE1 1 
ATOM   4893  O  OE2 . GLU B 1 242 ? -32.140 14.579  56.063  1.00 68.98  ? 221 GLU B OE2 1 
ATOM   4894  N  N   . HIS B 1 243 ? -33.793 12.898  50.558  1.00 31.09  ? 222 HIS B N   1 
ATOM   4895  C  CA  . HIS B 1 243 ? -34.235 11.546  50.234  1.00 28.25  ? 222 HIS B CA  1 
ATOM   4896  C  C   . HIS B 1 243 ? -33.550 11.014  48.983  1.00 29.85  ? 222 HIS B C   1 
ATOM   4897  O  O   . HIS B 1 243 ? -33.329 9.804   48.864  1.00 31.28  ? 222 HIS B O   1 
ATOM   4898  C  CB  . HIS B 1 243 ? -35.760 11.537  50.092  1.00 25.52  ? 222 HIS B CB  1 
ATOM   4899  C  CG  . HIS B 1 243 ? -36.475 11.653  51.399  1.00 32.58  ? 222 HIS B CG  1 
ATOM   4900  N  ND1 . HIS B 1 243 ? -36.797 10.558  52.168  1.00 38.42  ? 222 HIS B ND1 1 
ATOM   4901  C  CD2 . HIS B 1 243 ? -36.929 12.739  52.075  1.00 29.54  ? 222 HIS B CD2 1 
ATOM   4902  C  CE1 . HIS B 1 243 ? -37.431 10.961  53.256  1.00 37.58  ? 222 HIS B CE1 1 
ATOM   4903  N  NE2 . HIS B 1 243 ? -37.527 12.279  53.221  1.00 37.40  ? 222 HIS B NE2 1 
ATOM   4904  N  N   . MET B 1 244 ? -33.196 11.890  48.039  1.00 24.74  ? 223 MET B N   1 
ATOM   4905  C  CA  . MET B 1 244 ? -32.439 11.420  46.883  1.00 30.20  ? 223 MET B CA  1 
ATOM   4906  C  C   . MET B 1 244 ? -31.010 11.065  47.283  1.00 37.03  ? 223 MET B C   1 
ATOM   4907  O  O   . MET B 1 244 ? -30.443 10.086  46.786  1.00 30.91  ? 223 MET B O   1 
ATOM   4908  C  CB  . MET B 1 244 ? -32.455 12.471  45.769  1.00 31.27  ? 223 MET B CB  1 
ATOM   4909  C  CG  . MET B 1 244 ? -33.876 12.656  45.145  1.00 28.90  ? 223 MET B CG  1 
ATOM   4910  S  SD  . MET B 1 244 ? -34.482 11.087  44.463  1.00 33.33  ? 223 MET B SD  1 
ATOM   4911  C  CE  . MET B 1 244 ? -35.651 10.528  45.719  1.00 28.84  ? 223 MET B CE  1 
ATOM   4912  N  N   . ALA B 1 245 ? -30.413 11.847  48.182  1.00 35.07  ? 224 ALA B N   1 
ATOM   4913  C  CA  . ALA B 1 245 ? -29.105 11.479  48.712  1.00 34.51  ? 224 ALA B CA  1 
ATOM   4914  C  C   . ALA B 1 245 ? -29.151 10.126  49.403  1.00 32.59  ? 224 ALA B C   1 
ATOM   4915  O  O   . ALA B 1 245 ? -28.182 9.363   49.337  1.00 37.91  ? 224 ALA B O   1 
ATOM   4916  C  CB  . ALA B 1 245 ? -28.614 12.565  49.674  1.00 31.87  ? 224 ALA B CB  1 
ATOM   4917  N  N   . GLN B 1 246 ? -30.275 9.803   50.041  1.00 30.78  ? 225 GLN B N   1 
ATOM   4918  C  CA  . GLN B 1 246 ? -30.489 8.522   50.689  1.00 33.61  ? 225 GLN B CA  1 
ATOM   4919  C  C   . GLN B 1 246 ? -31.128 7.473   49.775  1.00 34.16  ? 225 GLN B C   1 
ATOM   4920  O  O   . GLN B 1 246 ? -31.603 6.450   50.274  1.00 36.43  ? 225 GLN B O   1 
ATOM   4921  C  CB  . GLN B 1 246 ? -31.360 8.707   51.933  1.00 32.35  ? 225 GLN B CB  1 
ATOM   4922  C  CG  . GLN B 1 246 ? -30.737 9.608   53.014  1.00 35.48  ? 225 GLN B CG  1 
ATOM   4923  C  CD  . GLN B 1 246 ? -31.759 10.079  54.035  1.00 45.11  ? 225 GLN B CD  1 
ATOM   4924  O  OE1 . GLN B 1 246 ? -32.957 9.826   53.901  1.00 56.63  ? 225 GLN B OE1 1 
ATOM   4925  N  NE2 . GLN B 1 246 ? -31.285 10.777  55.065  1.00 57.64  ? 225 GLN B NE2 1 
ATOM   4926  N  N   . LEU B 1 247 ? -31.145 7.686   48.459  1.00 32.28  ? 226 LEU B N   1 
ATOM   4927  C  CA  . LEU B 1 247 ? -31.787 6.719   47.563  1.00 35.83  ? 226 LEU B CA  1 
ATOM   4928  C  C   . LEU B 1 247 ? -31.121 5.348   47.666  1.00 31.96  ? 226 LEU B C   1 
ATOM   4929  O  O   . LEU B 1 247 ? -29.904 5.232   47.522  1.00 34.13  ? 226 LEU B O   1 
ATOM   4930  C  CB  . LEU B 1 247 ? -31.698 7.215   46.119  1.00 32.98  ? 226 LEU B CB  1 
ATOM   4931  C  CG  . LEU B 1 247 ? -32.594 6.516   45.097  1.00 31.71  ? 226 LEU B CG  1 
ATOM   4932  C  CD1 . LEU B 1 247 ? -34.091 6.707   45.402  1.00 34.35  ? 226 LEU B CD1 1 
ATOM   4933  C  CD2 . LEU B 1 247 ? -32.234 7.028   43.709  1.00 31.51  ? 226 LEU B CD2 1 
ATOM   4934  N  N   . THR B 1 248 ? -31.912 4.300   47.868  1.00 29.96  ? 227 THR B N   1 
ATOM   4935  C  CA  . THR B 1 248 ? -31.354 2.955   47.999  1.00 34.49  ? 227 THR B CA  1 
ATOM   4936  C  C   . THR B 1 248 ? -32.020 2.003   47.021  1.00 34.74  ? 227 THR B C   1 
ATOM   4937  O  O   . THR B 1 248 ? -33.093 2.294   46.495  1.00 34.93  ? 227 THR B O   1 
ATOM   4938  C  CB  . THR B 1 248 ? -31.531 2.388   49.417  1.00 37.59  ? 227 THR B CB  1 
ATOM   4939  O  OG1 . THR B 1 248 ? -32.916 2.416   49.753  1.00 40.65  ? 227 THR B OG1 1 
ATOM   4940  C  CG2 . THR B 1 248 ? -30.730 3.198   50.441  1.00 33.01  ? 227 THR B CG2 1 
ATOM   4941  N  N   . ASP B 1 249 ? -31.404 0.831   46.811  1.00 29.79  ? 228 ASP B N   1 
ATOM   4942  C  CA  . ASP B 1 249 ? -31.978 -0.135  45.890  1.00 32.30  ? 228 ASP B CA  1 
ATOM   4943  C  C   . ASP B 1 249 ? -32.631 -1.268  46.686  1.00 37.33  ? 228 ASP B C   1 
ATOM   4944  O  O   . ASP B 1 249 ? -32.769 -1.184  47.910  1.00 34.38  ? 228 ASP B O   1 
ATOM   4945  C  CB  . ASP B 1 249 ? -30.911 -0.601  44.894  1.00 34.17  ? 228 ASP B CB  1 
ATOM   4946  C  CG  . ASP B 1 249 ? -29.717 -1.256  45.564  1.00 54.67  ? 228 ASP B CG  1 
ATOM   4947  O  OD1 . ASP B 1 249 ? -29.878 -1.846  46.664  1.00 42.87  ? 228 ASP B OD1 1 
ATOM   4948  O  OD2 . ASP B 1 249 ? -28.612 -1.173  44.977  1.00 58.04  ? 228 ASP B OD2 1 
ATOM   4949  N  N   . ALA B 1 250 ? -33.049 -2.336  45.993  1.00 34.11  ? 229 ALA B N   1 
ATOM   4950  C  CA  . ALA B 1 250 ? -33.853 -3.371  46.647  1.00 46.96  ? 229 ALA B CA  1 
ATOM   4951  C  C   . ALA B 1 250 ? -33.079 -4.122  47.732  1.00 47.00  ? 229 ALA B C   1 
ATOM   4952  O  O   . ALA B 1 250 ? -33.689 -4.631  48.679  1.00 54.90  ? 229 ALA B O   1 
ATOM   4953  C  CB  . ALA B 1 250 ? -34.398 -4.358  45.609  1.00 41.31  ? 229 ALA B CB  1 
ATOM   4954  N  N   . SER B 1 251 ? -31.758 -4.161  47.637  1.00 42.89  ? 230 SER B N   1 
ATOM   4955  C  CA  . SER B 1 251 ? -30.905 -4.778  48.645  1.00 47.62  ? 230 SER B CA  1 
ATOM   4956  C  C   . SER B 1 251 ? -30.589 -3.854  49.819  1.00 53.78  ? 230 SER B C   1 
ATOM   4957  O  O   . SER B 1 251 ? -29.815 -4.240  50.701  1.00 53.94  ? 230 SER B O   1 
ATOM   4958  C  CB  . SER B 1 251 ? -29.606 -5.235  47.986  1.00 42.71  ? 230 SER B CB  1 
ATOM   4959  O  OG  . SER B 1 251 ? -28.761 -4.128  47.747  1.00 51.18  ? 230 SER B OG  1 
ATOM   4960  N  N   . GLY B 1 252 ? -31.155 -2.647  49.854  1.00 43.90  ? 231 GLY B N   1 
ATOM   4961  C  CA  . GLY B 1 252 ? -30.862 -1.698  50.903  1.00 41.92  ? 231 GLY B CA  1 
ATOM   4962  C  C   . GLY B 1 252 ? -29.578 -0.921  50.742  1.00 38.21  ? 231 GLY B C   1 
ATOM   4963  O  O   . GLY B 1 252 ? -29.293 -0.071  51.592  1.00 39.01  ? 231 GLY B O   1 
ATOM   4964  N  N   . GLU B 1 253 ? -28.796 -1.181  49.693  1.00 36.37  ? 232 GLU B N   1 
ATOM   4965  C  CA  . GLU B 1 253 ? -27.565 -0.452  49.424  1.00 33.00  ? 232 GLU B CA  1 
ATOM   4966  C  C   . GLU B 1 253 ? -27.844 0.887   48.759  1.00 46.94  ? 232 GLU B C   1 
ATOM   4967  O  O   . GLU B 1 253 ? -28.766 1.029   47.946  1.00 35.75  ? 232 GLU B O   1 
ATOM   4968  C  CB  . GLU B 1 253 ? -26.647 -1.245  48.491  1.00 42.70  ? 232 GLU B CB  1 
ATOM   4969  C  CG  . GLU B 1 253 ? -26.130 -2.556  49.055  1.00 60.06  ? 232 GLU B CG  1 
ATOM   4970  C  CD  . GLU B 1 253 ? -24.846 -2.368  49.835  1.00 76.61  ? 232 GLU B CD  1 
ATOM   4971  O  OE1 . GLU B 1 253 ? -24.913 -1.802  50.949  1.00 71.02  ? 232 GLU B OE1 1 
ATOM   4972  O  OE2 . GLU B 1 253 ? -23.770 -2.759  49.320  1.00 86.15  ? 232 GLU B OE2 1 
ATOM   4973  N  N   . ARG B 1 254 ? -26.982 1.850   49.058  1.00 35.30  ? 233 ARG B N   1 
ATOM   4974  C  CA  . ARG B 1 254 ? -27.114 3.186   48.512  1.00 38.24  ? 233 ARG B CA  1 
ATOM   4975  C  C   . ARG B 1 254 ? -26.859 3.173   47.007  1.00 38.46  ? 233 ARG B C   1 
ATOM   4976  O  O   . ARG B 1 254 ? -25.927 2.532   46.527  1.00 35.92  ? 233 ARG B O   1 
ATOM   4977  C  CB  . ARG B 1 254 ? -26.135 4.108   49.222  1.00 45.03  ? 233 ARG B CB  1 
ATOM   4978  C  CG  . ARG B 1 254 ? -26.580 5.520   49.276  1.00 49.52  ? 233 ARG B CG  1 
ATOM   4979  C  CD  . ARG B 1 254 ? -25.722 6.268   50.262  1.00 58.38  ? 233 ARG B CD  1 
ATOM   4980  N  NE  . ARG B 1 254 ? -26.509 6.696   51.409  1.00 63.29  ? 233 ARG B NE  1 
ATOM   4981  C  CZ  . ARG B 1 254 ? -26.086 7.590   52.288  1.00 59.23  ? 233 ARG B CZ  1 
ATOM   4982  N  NH1 . ARG B 1 254 ? -24.877 8.126   52.193  1.00 49.53  ? 233 ARG B NH1 1 
ATOM   4983  N  NH2 . ARG B 1 254 ? -26.895 7.959   53.279  1.00 57.66  ? 233 ARG B NH2 1 
ATOM   4984  N  N   . VAL B 1 255 ? -27.719 3.851   46.254  1.00 32.99  ? 234 VAL B N   1 
ATOM   4985  C  CA  . VAL B 1 255 ? -27.515 4.010   44.819  1.00 31.89  ? 234 VAL B CA  1 
ATOM   4986  C  C   . VAL B 1 255 ? -26.348 4.966   44.577  1.00 33.26  ? 234 VAL B C   1 
ATOM   4987  O  O   . VAL B 1 255 ? -26.126 5.901   45.355  1.00 37.36  ? 234 VAL B O   1 
ATOM   4988  C  CB  . VAL B 1 255 ? -28.834 4.534   44.205  1.00 38.20  ? 234 VAL B CB  1 
ATOM   4989  C  CG1 . VAL B 1 255 ? -28.627 5.011   42.815  1.00 35.89  ? 234 VAL B CG1 1 
ATOM   4990  C  CG2 . VAL B 1 255 ? -29.935 3.454   44.273  1.00 31.67  ? 234 VAL B CG2 1 
ATOM   4991  N  N   . ASP B 1 256 ? -25.588 4.738   43.496  1.00 35.73  ? 235 ASP B N   1 
ATOM   4992  C  CA  . ASP B 1 256 ? -24.449 5.614   43.208  1.00 37.95  ? 235 ASP B CA  1 
ATOM   4993  C  C   . ASP B 1 256 ? -24.890 7.067   43.017  1.00 34.88  ? 235 ASP B C   1 
ATOM   4994  O  O   . ASP B 1 256 ? -26.036 7.366   42.670  1.00 33.21  ? 235 ASP B O   1 
ATOM   4995  C  CB  . ASP B 1 256 ? -23.658 5.146   41.981  1.00 39.99  ? 235 ASP B CB  1 
ATOM   4996  C  CG  . ASP B 1 256 ? -24.427 5.287   40.677  1.00 42.94  ? 235 ASP B CG  1 
ATOM   4997  O  OD1 . ASP B 1 256 ? -24.424 6.385   40.068  1.00 48.64  ? 235 ASP B OD1 1 
ATOM   4998  O  OD2 . ASP B 1 256 ? -25.020 4.287   40.246  1.00 57.50  ? 235 ASP B OD2 1 
ATOM   4999  N  N   . ALA B 1 257 ? -23.942 7.978   43.258  1.00 32.01  ? 236 ALA B N   1 
ATOM   5000  C  CA  . ALA B 1 257 ? -24.264 9.399   43.342  1.00 35.90  ? 236 ALA B CA  1 
ATOM   5001  C  C   . ALA B 1 257 ? -24.782 9.959   42.011  1.00 33.82  ? 236 ALA B C   1 
ATOM   5002  O  O   . ALA B 1 257 ? -25.690 10.803  42.001  1.00 29.45  ? 236 ALA B O   1 
ATOM   5003  C  CB  . ALA B 1 257 ? -23.035 10.174  43.826  1.00 32.78  ? 236 ALA B CB  1 
ATOM   5004  N  N   . ARG B 1 258 ? -24.220 9.523   40.875  1.00 30.77  ? 237 ARG B N   1 
ATOM   5005  C  CA  . ARG B 1 258 ? -24.684 10.069  39.597  1.00 31.34  ? 237 ARG B CA  1 
ATOM   5006  C  C   . ARG B 1 258 ? -26.120 9.650   39.307  1.00 29.15  ? 237 ARG B C   1 
ATOM   5007  O  O   . ARG B 1 258 ? -26.917 10.464  38.824  1.00 28.30  ? 237 ARG B O   1 
ATOM   5008  C  CB  . ARG B 1 258 ? -23.780 9.644   38.443  1.00 27.53  ? 237 ARG B CB  1 
ATOM   5009  C  CG  . ARG B 1 258 ? -23.995 10.462  37.163  1.00 30.61  ? 237 ARG B CG  1 
ATOM   5010  C  CD  . ARG B 1 258 ? -22.894 10.204  36.154  1.00 26.41  ? 237 ARG B CD  1 
ATOM   5011  N  NE  . ARG B 1 258 ? -22.949 11.093  34.985  1.00 33.85  ? 237 ARG B NE  1 
ATOM   5012  C  CZ  . ARG B 1 258 ? -22.308 12.253  34.880  1.00 36.69  ? 237 ARG B CZ  1 
ATOM   5013  N  NH1 . ARG B 1 258 ? -21.615 12.759  35.891  1.00 33.30  ? 237 ARG B NH1 1 
ATOM   5014  N  NH2 . ARG B 1 258 ? -22.350 12.922  33.725  1.00 35.36  ? 237 ARG B NH2 1 
ATOM   5015  N  N   . THR B 1 259 ? -26.466 8.395   39.610  1.00 31.83  ? 238 THR B N   1 
ATOM   5016  C  CA  . THR B 1 259 ? -27.843 7.923   39.433  1.00 31.81  ? 238 THR B CA  1 
ATOM   5017  C  C   . THR B 1 259 ? -28.796 8.671   40.358  1.00 32.84  ? 238 THR B C   1 
ATOM   5018  O  O   . THR B 1 259 ? -29.907 9.051   39.956  1.00 24.95  ? 238 THR B O   1 
ATOM   5019  C  CB  . THR B 1 259 ? -27.902 6.412   39.686  1.00 30.73  ? 238 THR B CB  1 
ATOM   5020  O  OG1 . THR B 1 259 ? -27.015 5.751   38.778  1.00 35.34  ? 238 THR B OG1 1 
ATOM   5021  C  CG2 . THR B 1 259 ? -29.336 5.831   39.492  1.00 30.71  ? 238 THR B CG2 1 
ATOM   5022  N  N   . ALA B 1 260 ? -28.373 8.913   41.601  1.00 28.76  ? 239 ALA B N   1 
ATOM   5023  C  CA  . ALA B 1 260 ? -29.224 9.672   42.512  1.00 28.68  ? 239 ALA B CA  1 
ATOM   5024  C  C   . ALA B 1 260 ? -29.408 11.108  42.034  1.00 25.76  ? 239 ALA B C   1 
ATOM   5025  O  O   . ALA B 1 260 ? -30.487 11.686  42.208  1.00 28.66  ? 239 ALA B O   1 
ATOM   5026  C  CB  . ALA B 1 260 ? -28.648 9.626   43.934  1.00 26.26  ? 239 ALA B CB  1 
ATOM   5027  N  N   . GLY B 1 261 ? -28.365 11.712  41.458  1.00 20.91  ? 240 GLY B N   1 
ATOM   5028  C  CA  . GLY B 1 261 ? -28.510 13.032  40.865  1.00 24.29  ? 240 GLY B CA  1 
ATOM   5029  C  C   . GLY B 1 261 ? -29.430 13.021  39.654  1.00 31.04  ? 240 GLY B C   1 
ATOM   5030  O  O   . GLY B 1 261 ? -30.150 13.996  39.401  1.00 26.60  ? 240 GLY B O   1 
ATOM   5031  N  N   . ILE B 1 262 ? -29.436 11.914  38.907  1.00 25.97  ? 241 ILE B N   1 
ATOM   5032  C  CA  . ILE B 1 262 ? -30.356 11.770  37.778  1.00 27.77  ? 241 ILE B CA  1 
ATOM   5033  C  C   . ILE B 1 262 ? -31.793 11.682  38.272  1.00 27.45  ? 241 ILE B C   1 
ATOM   5034  O  O   . ILE B 1 262 ? -32.705 12.274  37.675  1.00 25.80  ? 241 ILE B O   1 
ATOM   5035  C  CB  . ILE B 1 262 ? -29.942 10.550  36.927  1.00 27.64  ? 241 ILE B CB  1 
ATOM   5036  C  CG1 . ILE B 1 262 ? -28.760 10.942  36.034  1.00 25.56  ? 241 ILE B CG1 1 
ATOM   5037  C  CG2 . ILE B 1 262 ? -31.147 9.957   36.120  1.00 28.84  ? 241 ILE B CG2 1 
ATOM   5038  C  CD1 . ILE B 1 262 ? -27.874 9.765   35.602  1.00 28.98  ? 241 ILE B CD1 1 
ATOM   5039  N  N   . GLU B 1 263 ? -32.016 10.984  39.394  1.00 24.36  ? 242 GLU B N   1 
ATOM   5040  C  CA  . GLU B 1 263 ? -33.364 10.924  39.956  1.00 30.17  ? 242 GLU B CA  1 
ATOM   5041  C  C   . GLU B 1 263 ? -33.792 12.253  40.585  1.00 29.08  ? 242 GLU B C   1 
ATOM   5042  O  O   . GLU B 1 263 ? -34.982 12.599  40.541  1.00 26.31  ? 242 GLU B O   1 
ATOM   5043  C  CB  . GLU B 1 263 ? -33.477 9.770   40.965  1.00 27.08  ? 242 GLU B CB  1 
ATOM   5044  C  CG  . GLU B 1 263 ? -33.241 8.382   40.335  1.00 25.12  ? 242 GLU B CG  1 
ATOM   5045  C  CD  . GLU B 1 263 ? -34.188 8.037   39.141  1.00 34.33  ? 242 GLU B CD  1 
ATOM   5046  O  OE1 . GLU B 1 263 ? -34.776 8.916   38.463  1.00 32.39  ? 242 GLU B OE1 1 
ATOM   5047  O  OE2 . GLU B 1 263 ? -34.343 6.850   38.864  1.00 29.24  ? 242 GLU B OE2 1 
ATOM   5048  N  N   . LEU B 1 264 ? -32.862 13.007  41.165  1.00 29.45  ? 243 LEU B N   1 
ATOM   5049  C  CA  . LEU B 1 264 ? -33.193 14.362  41.608  1.00 25.93  ? 243 LEU B CA  1 
ATOM   5050  C  C   . LEU B 1 264 ? -33.660 15.229  40.433  1.00 22.47  ? 243 LEU B C   1 
ATOM   5051  O  O   . LEU B 1 264 ? -34.638 15.976  40.559  1.00 24.61  ? 243 LEU B O   1 
ATOM   5052  C  CB  . LEU B 1 264 ? -31.977 15.000  42.302  1.00 26.43  ? 243 LEU B CB  1 
ATOM   5053  C  CG  . LEU B 1 264 ? -32.191 16.444  42.798  1.00 22.62  ? 243 LEU B CG  1 
ATOM   5054  C  CD1 . LEU B 1 264 ? -33.135 16.510  43.993  1.00 28.97  ? 243 LEU B CD1 1 
ATOM   5055  C  CD2 . LEU B 1 264 ? -30.819 17.098  43.115  1.00 31.36  ? 243 LEU B CD2 1 
ATOM   5056  N  N   . GLN B 1 265 ? -32.996 15.122  39.269  1.00 21.15  ? 244 GLN B N   1 
ATOM   5057  C  CA  . GLN B 1 265 ? -33.458 15.843  38.088  1.00 25.20  ? 244 GLN B CA  1 
ATOM   5058  C  C   . GLN B 1 265 ? -34.807 15.329  37.597  1.00 24.02  ? 244 GLN B C   1 
ATOM   5059  O  O   . GLN B 1 265 ? -35.615 16.120  37.119  1.00 23.12  ? 244 GLN B O   1 
ATOM   5060  C  CB  . GLN B 1 265 ? -32.448 15.737  36.946  1.00 23.83  ? 244 GLN B CB  1 
ATOM   5061  C  CG  . GLN B 1 265 ? -31.100 16.311  37.240  1.00 27.65  ? 244 GLN B CG  1 
ATOM   5062  C  CD  . GLN B 1 265 ? -30.135 15.960  36.144  1.00 28.99  ? 244 GLN B CD  1 
ATOM   5063  O  OE1 . GLN B 1 265 ? -30.266 16.443  35.008  1.00 29.17  ? 244 GLN B OE1 1 
ATOM   5064  N  NE2 . GLN B 1 265 ? -29.166 15.116  36.456  1.00 27.75  ? 244 GLN B NE2 1 
ATOM   5065  N  N   . ASN B 1 266 ? -35.073 14.028  37.739  1.00 21.80  ? 245 ASN B N   1 
ATOM   5066  C  CA  . ASN B 1 266 ? -36.381 13.465  37.392  1.00 22.11  ? 245 ASN B CA  1 
ATOM   5067  C  C   . ASN B 1 266 ? -37.488 13.887  38.356  1.00 27.53  ? 245 ASN B C   1 
ATOM   5068  O  O   . ASN B 1 266 ? -38.645 13.544  38.099  1.00 24.37  ? 245 ASN B O   1 
ATOM   5069  C  CB  . ASN B 1 266 ? -36.299 11.940  37.313  1.00 23.94  ? 245 ASN B CB  1 
ATOM   5070  C  CG  . ASN B 1 266 ? -35.588 11.475  36.039  1.00 28.69  ? 245 ASN B CG  1 
ATOM   5071  O  OD1 . ASN B 1 266 ? -35.609 12.168  35.045  1.00 26.38  ? 245 ASN B OD1 1 
ATOM   5072  N  ND2 . ASN B 1 266 ? -34.945 10.327  36.089  1.00 25.84  ? 245 ASN B ND2 1 
ATOM   5073  N  N   . LEU B 1 267 ? -37.179 14.636  39.424  1.00 23.78  ? 246 LEU B N   1 
ATOM   5074  C  CA  . LEU B 1 267 ? -38.211 15.234  40.272  1.00 22.15  ? 246 LEU B CA  1 
ATOM   5075  C  C   . LEU B 1 267 ? -38.238 16.760  40.210  1.00 25.06  ? 246 LEU B C   1 
ATOM   5076  O  O   . LEU B 1 267 ? -38.984 17.384  40.981  1.00 28.53  ? 246 LEU B O   1 
ATOM   5077  C  CB  . LEU B 1 267 ? -38.041 14.771  41.733  1.00 24.15  ? 246 LEU B CB  1 
ATOM   5078  C  CG  . LEU B 1 267 ? -38.124 13.269  41.938  1.00 28.26  ? 246 LEU B CG  1 
ATOM   5079  C  CD1 . LEU B 1 267 ? -37.617 12.890  43.362  1.00 33.13  ? 246 LEU B CD1 1 
ATOM   5080  C  CD2 . LEU B 1 267 ? -39.578 12.821  41.756  1.00 22.77  ? 246 LEU B CD2 1 
ATOM   5081  N  N   . THR B 1 268 ? -37.466 17.376  39.303  1.00 21.68  ? 247 THR B N   1 
ATOM   5082  C  CA  . THR B 1 268 ? -37.453 18.826  39.123  1.00 21.82  ? 247 THR B CA  1 
ATOM   5083  C  C   . THR B 1 268 ? -37.615 19.236  37.659  1.00 25.32  ? 247 THR B C   1 
ATOM   5084  O  O   . THR B 1 268 ? -38.393 20.139  37.354  1.00 21.72  ? 247 THR B O   1 
ATOM   5085  C  CB  . THR B 1 268 ? -36.147 19.428  39.668  1.00 27.91  ? 247 THR B CB  1 
ATOM   5086  O  OG1 . THR B 1 268 ? -35.043 18.615  39.243  1.00 26.97  ? 247 THR B OG1 1 
ATOM   5087  C  CG2 . THR B 1 268 ? -36.158 19.456  41.202  1.00 27.64  ? 247 THR B CG2 1 
ATOM   5088  N  N   . ARG B 1 269 ? -36.838 18.647  36.759  1.00 23.65  ? 248 ARG B N   1 
ATOM   5089  C  CA  . ARG B 1 269 ? -36.991 18.951  35.335  1.00 20.69  ? 248 ARG B CA  1 
ATOM   5090  C  C   . ARG B 1 269 ? -38.420 18.745  34.804  1.00 20.81  ? 248 ARG B C   1 
ATOM   5091  O  O   . ARG B 1 269 ? -38.873 19.574  33.993  1.00 21.64  ? 248 ARG B O   1 
ATOM   5092  C  CB  . ARG B 1 269 ? -36.000 18.093  34.512  1.00 23.91  ? 248 ARG B CB  1 
ATOM   5093  C  CG  . ARG B 1 269 ? -36.116 18.343  32.966  1.00 21.89  ? 248 ARG B CG  1 
ATOM   5094  C  CD  . ARG B 1 269 ? -35.565 17.152  32.145  1.00 22.32  ? 248 ARG B CD  1 
ATOM   5095  N  NE  . ARG B 1 269 ? -36.408 15.970  32.330  1.00 26.11  ? 248 ARG B NE  1 
ATOM   5096  C  CZ  . ARG B 1 269 ? -36.099 14.947  33.122  1.00 25.56  ? 248 ARG B CZ  1 
ATOM   5097  N  NH1 . ARG B 1 269 ? -34.920 14.881  33.750  1.00 28.41  ? 248 ARG B NH1 1 
ATOM   5098  N  NH2 . ARG B 1 269 ? -36.991 13.972  33.297  1.00 26.05  ? 248 ARG B NH2 1 
ATOM   5099  N  N   . PRO B 1 270 ? -39.159 17.691  35.175  1.00 21.32  ? 249 PRO B N   1 
ATOM   5100  C  CA  . PRO B 1 270 ? -40.525 17.546  34.645  1.00 19.32  ? 249 PRO B CA  1 
ATOM   5101  C  C   . PRO B 1 270 ? -41.454 18.645  35.114  1.00 21.40  ? 249 PRO B C   1 
ATOM   5102  O  O   . PRO B 1 270 ? -42.430 18.965  34.421  1.00 22.97  ? 249 PRO B O   1 
ATOM   5103  C  CB  . PRO B 1 270 ? -40.976 16.178  35.174  1.00 19.39  ? 249 PRO B CB  1 
ATOM   5104  C  CG  . PRO B 1 270 ? -39.643 15.396  35.337  1.00 20.51  ? 249 PRO B CG  1 
ATOM   5105  C  CD  . PRO B 1 270 ? -38.730 16.485  35.907  1.00 23.20  ? 249 PRO B CD  1 
ATOM   5106  N  N   . THR B 1 271 ? -41.159 19.256  36.256  1.00 20.09  ? 250 THR B N   1 
ATOM   5107  C  CA  . THR B 1 271 ? -41.915 20.439  36.653  1.00 21.12  ? 250 THR B CA  1 
ATOM   5108  C  C   . THR B 1 271 ? -41.646 21.598  35.704  1.00 20.39  ? 250 THR B C   1 
ATOM   5109  O  O   . THR B 1 271 ? -42.572 22.317  35.305  1.00 25.04  ? 250 THR B O   1 
ATOM   5110  C  CB  . THR B 1 271 ? -41.572 20.790  38.106  1.00 23.83  ? 250 THR B CB  1 
ATOM   5111  O  OG1 . THR B 1 271 ? -41.793 19.618  38.897  1.00 23.59  ? 250 THR B OG1 1 
ATOM   5112  C  CG2 . THR B 1 271 ? -42.522 21.907  38.628  1.00 21.07  ? 250 THR B CG2 1 
ATOM   5113  N  N   . VAL B 1 272 ? -40.385 21.801  35.330  1.00 20.31  ? 251 VAL B N   1 
ATOM   5114  C  CA  . VAL B 1 272 ? -40.058 22.799  34.307  1.00 20.93  ? 251 VAL B CA  1 
ATOM   5115  C  C   . VAL B 1 272 ? -40.873 22.543  33.034  1.00 23.36  ? 251 VAL B C   1 
ATOM   5116  O  O   . VAL B 1 272 ? -41.340 23.481  32.365  1.00 22.20  ? 251 VAL B O   1 
ATOM   5117  C  CB  . VAL B 1 272 ? -38.546 22.754  33.996  1.00 24.04  ? 251 VAL B CB  1 
ATOM   5118  C  CG1 . VAL B 1 272 ? -38.221 23.731  32.876  1.00 20.02  ? 251 VAL B CG1 1 
ATOM   5119  C  CG2 . VAL B 1 272 ? -37.710 23.078  35.262  1.00 21.88  ? 251 VAL B CG2 1 
ATOM   5120  N  N   . ALA B 1 273 ? -40.992 21.260  32.652  1.00 18.83  ? 252 ALA B N   1 
ATOM   5121  C  CA  . ALA B 1 273 ? -41.701 20.876  31.435  1.00 21.12  ? 252 ALA B CA  1 
ATOM   5122  C  C   . ALA B 1 273 ? -43.174 21.260  31.463  1.00 23.85  ? 252 ALA B C   1 
ATOM   5123  O  O   . ALA B 1 273 ? -43.797 21.314  30.399  1.00 21.06  ? 252 ALA B O   1 
ATOM   5124  C  CB  . ALA B 1 273 ? -41.562 19.367  31.192  1.00 20.09  ? 252 ALA B CB  1 
ATOM   5125  N  N   . VAL B 1 274 ? -43.746 21.561  32.631  1.00 19.03  ? 253 VAL B N   1 
ATOM   5126  C  CA  . VAL B 1 274 ? -45.127 22.048  32.627  1.00 20.60  ? 253 VAL B CA  1 
ATOM   5127  C  C   . VAL B 1 274 ? -45.243 23.348  31.821  1.00 21.39  ? 253 VAL B C   1 
ATOM   5128  O  O   . VAL B 1 274 ? -46.339 23.725  31.402  1.00 21.58  ? 253 VAL B O   1 
ATOM   5129  C  CB  . VAL B 1 274 ? -45.642 22.222  34.080  1.00 21.70  ? 253 VAL B CB  1 
ATOM   5130  C  CG1 . VAL B 1 274 ? -47.124 22.643  34.099  1.00 22.66  ? 253 VAL B CG1 1 
ATOM   5131  C  CG2 . VAL B 1 274 ? -45.511 20.906  34.815  1.00 21.87  ? 253 VAL B CG2 1 
ATOM   5132  N  N   . GLY B 1 275 ? -44.121 24.024  31.581  1.00 20.76  ? 254 GLY B N   1 
ATOM   5133  C  CA  . GLY B 1 275 ? -44.103 25.192  30.713  1.00 21.28  ? 254 GLY B CA  1 
ATOM   5134  C  C   . GLY B 1 275 ? -44.704 24.949  29.344  1.00 20.47  ? 254 GLY B C   1 
ATOM   5135  O  O   . GLY B 1 275 ? -45.305 25.859  28.758  1.00 21.75  ? 254 GLY B O   1 
ATOM   5136  N  N   . PHE B 1 276 ? -44.565 23.728  28.803  1.00 21.97  ? 255 PHE B N   1 
ATOM   5137  C  CA  . PHE B 1 276 ? -45.217 23.433  27.527  1.00 21.05  ? 255 PHE B CA  1 
ATOM   5138  C  C   . PHE B 1 276 ? -46.734 23.531  27.648  1.00 24.18  ? 255 PHE B C   1 
ATOM   5139  O  O   . PHE B 1 276 ? -47.402 24.144  26.801  1.00 22.72  ? 255 PHE B O   1 
ATOM   5140  C  CB  . PHE B 1 276 ? -44.814 22.044  27.034  1.00 18.99  ? 255 PHE B CB  1 
ATOM   5141  C  CG  . PHE B 1 276 ? -43.402 22.003  26.504  1.00 23.34  ? 255 PHE B CG  1 
ATOM   5142  C  CD1 . PHE B 1 276 ? -43.152 22.314  25.163  1.00 20.01  ? 255 PHE B CD1 1 
ATOM   5143  C  CD2 . PHE B 1 276 ? -42.328 21.741  27.358  1.00 21.35  ? 255 PHE B CD2 1 
ATOM   5144  C  CE1 . PHE B 1 276 ? -41.866 22.282  24.653  1.00 23.29  ? 255 PHE B CE1 1 
ATOM   5145  C  CE2 . PHE B 1 276 ? -41.018 21.729  26.868  1.00 24.37  ? 255 PHE B CE2 1 
ATOM   5146  C  CZ  . PHE B 1 276 ? -40.782 22.009  25.508  1.00 25.42  ? 255 PHE B CZ  1 
ATOM   5147  N  N   . PHE B 1 277 ? -47.298 22.921  28.688  1.00 21.06  ? 256 PHE B N   1 
ATOM   5148  C  CA  . PHE B 1 277 ? -48.739 23.031  28.899  1.00 21.11  ? 256 PHE B CA  1 
ATOM   5149  C  C   . PHE B 1 277 ? -49.136 24.481  29.233  1.00 21.85  ? 256 PHE B C   1 
ATOM   5150  O  O   . PHE B 1 277 ? -50.220 24.932  28.862  1.00 20.21  ? 256 PHE B O   1 
ATOM   5151  C  CB  . PHE B 1 277 ? -49.187 22.095  30.024  1.00 18.78  ? 256 PHE B CB  1 
ATOM   5152  C  CG  . PHE B 1 277 ? -49.425 20.648  29.616  1.00 22.12  ? 256 PHE B CG  1 
ATOM   5153  C  CD1 . PHE B 1 277 ? -50.091 20.322  28.439  1.00 21.09  ? 256 PHE B CD1 1 
ATOM   5154  C  CD2 . PHE B 1 277 ? -49.009 19.614  30.465  1.00 21.73  ? 256 PHE B CD2 1 
ATOM   5155  C  CE1 . PHE B 1 277 ? -50.341 18.995  28.107  1.00 21.23  ? 256 PHE B CE1 1 
ATOM   5156  C  CE2 . PHE B 1 277 ? -49.254 18.276  30.145  1.00 22.64  ? 256 PHE B CE2 1 
ATOM   5157  C  CZ  . PHE B 1 277 ? -49.911 17.969  28.944  1.00 18.33  ? 256 PHE B CZ  1 
ATOM   5158  N  N   . ALA B 1 278 ? -48.288 25.215  29.962  1.00 20.46  ? 257 ALA B N   1 
ATOM   5159  C  CA  . ALA B 1 278 ? -48.620 26.609  30.260  1.00 21.88  ? 257 ALA B CA  1 
ATOM   5160  C  C   . ALA B 1 278 ? -48.729 27.434  28.981  1.00 21.57  ? 257 ALA B C   1 
ATOM   5161  O  O   . ALA B 1 278 ? -49.618 28.289  28.848  1.00 20.73  ? 257 ALA B O   1 
ATOM   5162  C  CB  . ALA B 1 278 ? -47.559 27.213  31.196  1.00 22.48  ? 257 ALA B CB  1 
ATOM   5163  N  N   . SER B 1 279 ? -47.829 27.200  28.019  1.00 20.29  ? 258 SER B N   1 
ATOM   5164  C  CA  . SER B 1 279 ? -47.925 27.966  26.792  1.00 22.61  ? 258 SER B CA  1 
ATOM   5165  C  C   . SER B 1 279 ? -49.189 27.569  26.027  1.00 20.96  ? 258 SER B C   1 
ATOM   5166  O  O   . SER B 1 279 ? -49.911 28.436  25.507  1.00 21.85  ? 258 SER B O   1 
ATOM   5167  C  CB  . SER B 1 279 ? -46.625 27.809  25.973  1.00 28.43  ? 258 SER B CB  1 
ATOM   5168  O  OG  . SER B 1 279 ? -46.598 26.568  25.316  1.00 35.04  ? 258 SER B OG  1 
ATOM   5169  N  N   . PHE B 1 280 ? -49.533 26.280  26.013  1.00 18.00  ? 259 PHE B N   1 
ATOM   5170  C  CA  . PHE B 1 280 ? -50.829 25.917  25.407  1.00 21.24  ? 259 PHE B CA  1 
ATOM   5171  C  C   . PHE B 1 280 ? -52.009 26.516  26.177  1.00 24.71  ? 259 PHE B C   1 
ATOM   5172  O  O   . PHE B 1 280 ? -53.028 26.868  25.578  1.00 20.03  ? 259 PHE B O   1 
ATOM   5173  C  CB  . PHE B 1 280 ? -51.016 24.406  25.353  1.00 19.15  ? 259 PHE B CB  1 
ATOM   5174  C  CG  . PHE B 1 280 ? -50.197 23.716  24.278  1.00 23.56  ? 259 PHE B CG  1 
ATOM   5175  C  CD1 . PHE B 1 280 ? -50.310 24.086  22.947  1.00 25.43  ? 259 PHE B CD1 1 
ATOM   5176  C  CD2 . PHE B 1 280 ? -49.338 22.686  24.624  1.00 25.28  ? 259 PHE B CD2 1 
ATOM   5177  C  CE1 . PHE B 1 280 ? -49.555 23.418  21.949  1.00 25.55  ? 259 PHE B CE1 1 
ATOM   5178  C  CE2 . PHE B 1 280 ? -48.582 22.032  23.645  1.00 24.83  ? 259 PHE B CE2 1 
ATOM   5179  C  CZ  . PHE B 1 280 ? -48.707 22.392  22.315  1.00 21.98  ? 259 PHE B CZ  1 
ATOM   5180  N  N   . ALA B 1 281 ? -51.919 26.610  27.507  1.00 20.33  ? 260 ALA B N   1 
ATOM   5181  C  CA  . ALA B 1 281 ? -53.024 27.236  28.242  1.00 24.32  ? 260 ALA B CA  1 
ATOM   5182  C  C   . ALA B 1 281 ? -53.229 28.697  27.831  1.00 20.55  ? 260 ALA B C   1 
ATOM   5183  O  O   . ALA B 1 281 ? -54.367 29.194  27.782  1.00 20.03  ? 260 ALA B O   1 
ATOM   5184  C  CB  . ALA B 1 281 ? -52.779 27.157  29.757  1.00 19.62  ? 260 ALA B CB  1 
ATOM   5185  N  N   . ALA B 1 282 ? -52.145 29.415  27.569  1.00 19.15  ? 261 ALA B N   1 
ATOM   5186  C  CA  . ALA B 1 282 ? -52.286 30.808  27.157  1.00 20.24  ? 261 ALA B CA  1 
ATOM   5187  C  C   . ALA B 1 282 ? -52.989 30.879  25.804  1.00 20.01  ? 261 ALA B C   1 
ATOM   5188  O  O   . ALA B 1 282 ? -53.905 31.689  25.607  1.00 19.11  ? 261 ALA B O   1 
ATOM   5189  C  CB  . ALA B 1 282 ? -50.902 31.481  27.121  1.00 19.58  ? 261 ALA B CB  1 
ATOM   5190  N  N   . VAL B 1 283 ? -52.633 29.970  24.889  1.00 20.43  ? 262 VAL B N   1 
ATOM   5191  C  CA  . VAL B 1 283 ? -53.347 29.893  23.611  1.00 21.66  ? 262 VAL B CA  1 
ATOM   5192  C  C   . VAL B 1 283 ? -54.825 29.607  23.850  1.00 18.65  ? 262 VAL B C   1 
ATOM   5193  O  O   . VAL B 1 283 ? -55.715 30.267  23.293  1.00 21.55  ? 262 VAL B O   1 
ATOM   5194  C  CB  . VAL B 1 283 ? -52.713 28.820  22.708  1.00 25.52  ? 262 VAL B CB  1 
ATOM   5195  C  CG1 . VAL B 1 283 ? -53.623 28.539  21.502  1.00 24.29  ? 262 VAL B CG1 1 
ATOM   5196  C  CG2 . VAL B 1 283 ? -51.313 29.238  22.236  1.00 23.11  ? 262 VAL B CG2 1 
ATOM   5197  N  N   . ALA B 1 284 ? -55.104 28.619  24.685  1.00 17.59  ? 263 ALA B N   1 
ATOM   5198  C  CA  . ALA B 1 284 ? -56.485 28.250  24.987  1.00 20.86  ? 263 ALA B CA  1 
ATOM   5199  C  C   . ALA B 1 284 ? -57.263 29.403  25.635  1.00 22.67  ? 263 ALA B C   1 
ATOM   5200  O  O   . ALA B 1 284 ? -58.459 29.577  25.363  1.00 20.95  ? 263 ALA B O   1 
ATOM   5201  C  CB  . ALA B 1 284 ? -56.482 27.030  25.915  1.00 19.18  ? 263 ALA B CB  1 
ATOM   5202  N  N   . LEU B 1 285 ? -56.608 30.198  26.495  1.00 21.59  ? 264 LEU B N   1 
ATOM   5203  C  CA  . LEU B 1 285 ? -57.313 31.336  27.086  1.00 23.42  ? 264 LEU B CA  1 
ATOM   5204  C  C   . LEU B 1 285 ? -57.646 32.392  26.032  1.00 24.15  ? 264 LEU B C   1 
ATOM   5205  O  O   . LEU B 1 285 ? -58.716 33.023  26.091  1.00 25.44  ? 264 LEU B O   1 
ATOM   5206  C  CB  . LEU B 1 285 ? -56.482 31.938  28.235  1.00 23.46  ? 264 LEU B CB  1 
ATOM   5207  C  CG  . LEU B 1 285 ? -56.413 31.089  29.516  1.00 21.94  ? 264 LEU B CG  1 
ATOM   5208  C  CD1 . LEU B 1 285 ? -55.313 31.580  30.473  1.00 21.24  ? 264 LEU B CD1 1 
ATOM   5209  C  CD2 . LEU B 1 285 ? -57.797 31.117  30.223  1.00 21.09  ? 264 LEU B CD2 1 
ATOM   5210  N  N   . ALA B 1 286 ? -56.720 32.644  25.102  1.00 23.74  ? 265 ALA B N   1 
ATOM   5211  C  CA  . ALA B 1 286 ? -57.012 33.527  23.979  1.00 22.62  ? 265 ALA B CA  1 
ATOM   5212  C  C   . ALA B 1 286 ? -58.150 32.983  23.126  1.00 22.22  ? 265 ALA B C   1 
ATOM   5213  O  O   . ALA B 1 286 ? -58.974 33.752  22.634  1.00 22.85  ? 265 ALA B O   1 
ATOM   5214  C  CB  . ALA B 1 286 ? -55.773 33.710  23.111  1.00 23.54  ? 265 ALA B CB  1 
ATOM   5215  N  N   . GLU B 1 287 ? -58.254 31.668  22.993  1.00 21.38  ? 266 GLU B N   1 
ATOM   5216  C  CA  . GLU B 1 287 ? -59.271 31.086  22.131  1.00 20.54  ? 266 GLU B CA  1 
ATOM   5217  C  C   . GLU B 1 287 ? -60.615 30.876  22.799  1.00 23.30  ? 266 GLU B C   1 
ATOM   5218  O  O   . GLU B 1 287 ? -61.586 30.562  22.091  1.00 24.30  ? 266 GLU B O   1 
ATOM   5219  C  CB  . GLU B 1 287 ? -58.773 29.745  21.588  1.00 21.81  ? 266 GLU B CB  1 
ATOM   5220  C  CG  . GLU B 1 287 ? -57.518 29.957  20.697  1.00 23.41  ? 266 GLU B CG  1 
ATOM   5221  C  CD  . GLU B 1 287 ? -57.067 28.685  20.015  1.00 37.37  ? 266 GLU B CD  1 
ATOM   5222  O  OE1 . GLU B 1 287 ? -57.333 27.605  20.571  1.00 39.52  ? 266 GLU B OE1 1 
ATOM   5223  O  OE2 . GLU B 1 287 ? -56.452 28.769  18.933  1.00 45.33  ? 266 GLU B OE2 1 
ATOM   5224  N  N   . ASN B 1 288 ? -60.692 30.986  24.120  1.00 24.21  ? 267 ASN B N   1 
ATOM   5225  C  CA  . ASN B 1 288 ? -61.897 30.641  24.883  1.00 22.69  ? 267 ASN B CA  1 
ATOM   5226  C  C   . ASN B 1 288 ? -62.182 31.768  25.855  1.00 21.72  ? 267 ASN B C   1 
ATOM   5227  O  O   . ASN B 1 288 ? -62.033 31.604  27.064  1.00 24.52  ? 267 ASN B O   1 
ATOM   5228  C  CB  . ASN B 1 288 ? -61.719 29.311  25.623  1.00 24.73  ? 267 ASN B CB  1 
ATOM   5229  C  CG  . ASN B 1 288 ? -61.538 28.147  24.653  1.00 29.80  ? 267 ASN B CG  1 
ATOM   5230  O  OD1 . ASN B 1 288 ? -62.513 27.577  24.199  1.00 27.71  ? 267 ASN B OD1 1 
ATOM   5231  N  ND2 . ASN B 1 288 ? -60.282 27.818  24.311  1.00 26.09  ? 267 ASN B ND2 1 
ATOM   5232  N  N   . PRO B 1 289 ? -62.559 32.948  25.358  1.00 26.42  ? 268 PRO B N   1 
ATOM   5233  C  CA  . PRO B 1 289 ? -62.691 34.093  26.280  1.00 25.25  ? 268 PRO B CA  1 
ATOM   5234  C  C   . PRO B 1 289 ? -63.817 33.954  27.288  1.00 26.53  ? 268 PRO B C   1 
ATOM   5235  O  O   . PRO B 1 289 ? -63.742 34.586  28.351  1.00 23.65  ? 268 PRO B O   1 
ATOM   5236  C  CB  . PRO B 1 289 ? -62.913 35.293  25.353  1.00 26.48  ? 268 PRO B CB  1 
ATOM   5237  C  CG  . PRO B 1 289 ? -63.265 34.721  24.011  1.00 31.78  ? 268 PRO B CG  1 
ATOM   5238  C  CD  . PRO B 1 289 ? -62.719 33.336  23.942  1.00 27.55  ? 268 PRO B CD  1 
ATOM   5239  N  N   . GLN B 1 290 ? -64.858 33.169  27.005  1.00 24.05  ? 269 GLN B N   1 
ATOM   5240  C  CA  . GLN B 1 290 ? -65.906 33.012  28.005  1.00 26.22  ? 269 GLN B CA  1 
ATOM   5241  C  C   . GLN B 1 290 ? -65.419 32.170  29.188  1.00 27.68  ? 269 GLN B C   1 
ATOM   5242  O  O   . GLN B 1 290 ? -65.778 32.451  30.338  1.00 23.63  ? 269 GLN B O   1 
ATOM   5243  C  CB  . GLN B 1 290 ? -67.153 32.399  27.366  1.00 31.77  ? 269 GLN B CB  1 
ATOM   5244  C  CG  . GLN B 1 290 ? -68.379 32.458  28.285  1.00 65.82  ? 269 GLN B CG  1 
ATOM   5245  C  CD  . GLN B 1 290 ? -69.495 31.515  27.853  1.00 93.42  ? 269 GLN B CD  1 
ATOM   5246  O  OE1 . GLN B 1 290 ? -69.957 30.678  28.639  1.00 82.37  ? 269 GLN B OE1 1 
ATOM   5247  N  NE2 . GLN B 1 290 ? -69.937 31.650  26.604  1.00 89.92  ? 269 GLN B NE2 1 
ATOM   5248  N  N   . TRP B 1 291 ? -64.574 31.151  28.938  1.00 22.09  ? 270 TRP B N   1 
ATOM   5249  C  CA  . TRP B 1 291 ? -63.946 30.423  30.053  1.00 25.35  ? 270 TRP B CA  1 
ATOM   5250  C  C   . TRP B 1 291 ? -62.993 31.316  30.835  1.00 19.29  ? 270 TRP B C   1 
ATOM   5251  O  O   . TRP B 1 291 ? -62.884 31.218  32.069  1.00 22.70  ? 270 TRP B O   1 
ATOM   5252  C  CB  . TRP B 1 291 ? -63.199 29.170  29.536  1.00 22.50  ? 270 TRP B CB  1 
ATOM   5253  C  CG  . TRP B 1 291 ? -64.171 28.002  29.443  1.00 25.59  ? 270 TRP B CG  1 
ATOM   5254  C  CD1 . TRP B 1 291 ? -64.816 27.546  28.319  1.00 25.84  ? 270 TRP B CD1 1 
ATOM   5255  C  CD2 . TRP B 1 291 ? -64.663 27.213  30.536  1.00 24.44  ? 270 TRP B CD2 1 
ATOM   5256  N  NE1 . TRP B 1 291 ? -65.680 26.518  28.656  1.00 27.98  ? 270 TRP B NE1 1 
ATOM   5257  C  CE2 . TRP B 1 291 ? -65.594 26.289  30.006  1.00 25.06  ? 270 TRP B CE2 1 
ATOM   5258  C  CE3 . TRP B 1 291 ? -64.359 27.160  31.901  1.00 24.94  ? 270 TRP B CE3 1 
ATOM   5259  C  CZ2 . TRP B 1 291 ? -66.237 25.336  30.800  1.00 28.02  ? 270 TRP B CZ2 1 
ATOM   5260  C  CZ3 . TRP B 1 291 ? -65.028 26.213  32.700  1.00 28.73  ? 270 TRP B CZ3 1 
ATOM   5261  C  CH2 . TRP B 1 291 ? -65.948 25.331  32.145  1.00 25.93  ? 270 TRP B CH2 1 
ATOM   5262  N  N   . ARG B 1 292 ? -62.255 32.164  30.123  1.00 23.81  ? 271 ARG B N   1 
ATOM   5263  C  CA  . ARG B 1 292 ? -61.368 33.101  30.784  1.00 22.39  ? 271 ARG B CA  1 
ATOM   5264  C  C   . ARG B 1 292 ? -62.137 33.988  31.761  1.00 22.51  ? 271 ARG B C   1 
ATOM   5265  O  O   . ARG B 1 292 ? -61.699 34.206  32.896  1.00 23.45  ? 271 ARG B O   1 
ATOM   5266  C  CB  . ARG B 1 292 ? -60.655 33.949  29.723  1.00 21.47  ? 271 ARG B CB  1 
ATOM   5267  C  CG  . ARG B 1 292 ? -59.599 34.851  30.317  1.00 23.30  ? 271 ARG B CG  1 
ATOM   5268  C  CD  . ARG B 1 292 ? -58.879 35.564  29.191  1.00 24.11  ? 271 ARG B CD  1 
ATOM   5269  N  NE  . ARG B 1 292 ? -57.802 36.385  29.734  1.00 25.20  ? 271 ARG B NE  1 
ATOM   5270  C  CZ  . ARG B 1 292 ? -56.955 37.086  28.994  1.00 24.28  ? 271 ARG B CZ  1 
ATOM   5271  N  NH1 . ARG B 1 292 ? -56.954 37.006  27.674  1.00 22.85  ? 271 ARG B NH1 1 
ATOM   5272  N  NH2 . ARG B 1 292 ? -56.088 37.894  29.598  1.00 25.19  ? 271 ARG B NH2 1 
ATOM   5273  N  N   . THR B 1 293 ? -63.287 34.507  31.328  1.00 23.30  ? 272 THR B N   1 
ATOM   5274  C  CA  . THR B 1 293 ? -64.115 35.327  32.206  1.00 25.56  ? 272 THR B CA  1 
ATOM   5275  C  C   . THR B 1 293 ? -64.594 34.538  33.413  1.00 24.80  ? 272 THR B C   1 
ATOM   5276  O  O   . THR B 1 293 ? -64.562 35.032  34.543  1.00 25.84  ? 272 THR B O   1 
ATOM   5277  C  CB  . THR B 1 293 ? -65.300 35.865  31.428  1.00 29.10  ? 272 THR B CB  1 
ATOM   5278  O  OG1 . THR B 1 293 ? -64.816 36.697  30.369  1.00 30.98  ? 272 THR B OG1 1 
ATOM   5279  C  CG2 . THR B 1 293 ? -66.206 36.666  32.369  1.00 32.21  ? 272 THR B CG2 1 
ATOM   5280  N  N   . ARG B 1 294 ? -65.039 33.299  33.196  1.00 23.67  ? 273 ARG B N   1 
ATOM   5281  C  CA  . ARG B 1 294 ? -65.491 32.479  34.315  1.00 22.86  ? 273 ARG B CA  1 
ATOM   5282  C  C   . ARG B 1 294 ? -64.381 32.251  35.322  1.00 25.32  ? 273 ARG B C   1 
ATOM   5283  O  O   . ARG B 1 294 ? -64.628 32.252  36.532  1.00 23.61  ? 273 ARG B O   1 
ATOM   5284  C  CB  . ARG B 1 294 ? -66.022 31.122  33.820  1.00 24.50  ? 273 ARG B CB  1 
ATOM   5285  C  CG  . ARG B 1 294 ? -67.309 31.247  33.021  1.00 32.50  ? 273 ARG B CG  1 
ATOM   5286  C  CD  . ARG B 1 294 ? -67.770 29.881  32.497  1.00 33.48  ? 273 ARG B CD  1 
ATOM   5287  N  NE  . ARG B 1 294 ? -68.096 28.940  33.567  1.00 25.62  ? 273 ARG B NE  1 
ATOM   5288  C  CZ  . ARG B 1 294 ? -68.600 27.733  33.354  1.00 37.93  ? 273 ARG B CZ  1 
ATOM   5289  N  NH1 . ARG B 1 294 ? -68.838 27.300  32.128  1.00 35.19  ? 273 ARG B NH1 1 
ATOM   5290  N  NH2 . ARG B 1 294 ? -68.842 26.932  34.394  1.00 32.37  ? 273 ARG B NH2 1 
ATOM   5291  N  N   . ILE B 1 295 ? -63.147 32.021  34.847  1.00 22.24  ? 274 ILE B N   1 
ATOM   5292  C  CA  . ILE B 1 295 ? -62.025 31.865  35.768  1.00 21.91  ? 274 ILE B CA  1 
ATOM   5293  C  C   . ILE B 1 295 ? -61.796 33.147  36.552  1.00 21.91  ? 274 ILE B C   1 
ATOM   5294  O  O   . ILE B 1 295 ? -61.555 33.115  37.760  1.00 23.27  ? 274 ILE B O   1 
ATOM   5295  C  CB  . ILE B 1 295 ? -60.756 31.442  34.996  1.00 23.03  ? 274 ILE B CB  1 
ATOM   5296  C  CG1 . ILE B 1 295 ? -60.926 30.009  34.458  1.00 24.61  ? 274 ILE B CG1 1 
ATOM   5297  C  CG2 . ILE B 1 295 ? -59.494 31.616  35.863  1.00 22.47  ? 274 ILE B CG2 1 
ATOM   5298  C  CD1 . ILE B 1 295 ? -59.954 29.660  33.313  1.00 22.68  ? 274 ILE B CD1 1 
ATOM   5299  N  N   . ASN B 1 296 ? -61.803 34.298  35.864  1.00 21.70  ? 275 ASN B N   1 
ATOM   5300  C  CA  . ASN B 1 296 ? -61.561 35.566  36.555  1.00 25.41  ? 275 ASN B CA  1 
ATOM   5301  C  C   . ASN B 1 296 ? -62.643 35.889  37.589  1.00 31.84  ? 275 ASN B C   1 
ATOM   5302  O  O   . ASN B 1 296 ? -62.376 36.582  38.580  1.00 28.60  ? 275 ASN B O   1 
ATOM   5303  C  CB  . ASN B 1 296 ? -61.473 36.685  35.523  1.00 20.73  ? 275 ASN B CB  1 
ATOM   5304  C  CG  . ASN B 1 296 ? -60.156 36.688  34.826  1.00 25.55  ? 275 ASN B CG  1 
ATOM   5305  O  OD1 . ASN B 1 296 ? -59.141 36.254  35.404  1.00 27.97  ? 275 ASN B OD1 1 
ATOM   5306  N  ND2 . ASN B 1 296 ? -60.141 37.159  33.589  1.00 22.09  ? 275 ASN B ND2 1 
ATOM   5307  N  N   . GLU B 1 297 ? -63.864 35.422  37.380  1.00 24.06  ? 276 GLU B N   1 
ATOM   5308  C  CA  . GLU B 1 297 ? -64.948 35.781  38.290  1.00 33.12  ? 276 GLU B CA  1 
ATOM   5309  C  C   . GLU B 1 297 ? -65.165 34.741  39.370  1.00 38.25  ? 276 GLU B C   1 
ATOM   5310  O  O   . GLU B 1 297 ? -65.983 34.954  40.262  1.00 34.09  ? 276 GLU B O   1 
ATOM   5311  C  CB  . GLU B 1 297 ? -66.236 36.049  37.489  1.00 25.93  ? 276 GLU B CB  1 
ATOM   5312  C  CG  . GLU B 1 297 ? -66.028 37.265  36.556  1.00 27.00  ? 276 GLU B CG  1 
ATOM   5313  C  CD  . GLU B 1 297 ? -67.240 37.656  35.695  1.00 40.58  ? 276 GLU B CD  1 
ATOM   5314  O  OE1 . GLU B 1 297 ? -68.367 37.188  35.939  1.00 43.51  ? 276 GLU B OE1 1 
ATOM   5315  O  OE2 . GLU B 1 297 ? -67.046 38.460  34.750  1.00 42.46  ? 276 GLU B OE2 1 
ATOM   5316  N  N   . SER B 1 298 ? -64.401 33.657  39.356  1.00 28.67  ? 277 SER B N   1 
ATOM   5317  C  CA  . SER B 1 298 ? -64.657 32.549  40.253  1.00 29.24  ? 277 SER B CA  1 
ATOM   5318  C  C   . SER B 1 298 ? -64.032 32.753  41.620  1.00 38.71  ? 277 SER B C   1 
ATOM   5319  O  O   . SER B 1 298 ? -62.957 33.332  41.767  1.00 38.62  ? 277 SER B O   1 
ATOM   5320  C  CB  . SER B 1 298 ? -64.125 31.248  39.655  1.00 33.62  ? 277 SER B CB  1 
ATOM   5321  O  OG  . SER B 1 298 ? -64.011 30.252  40.657  1.00 37.02  ? 277 SER B OG  1 
ATOM   5322  N  N   . GLU B 1 299 ? -64.698 32.204  42.623  1.00 38.46  ? 278 GLU B N   1 
ATOM   5323  C  CA  . GLU B 1 299 ? -64.157 32.170  43.967  1.00 52.30  ? 278 GLU B CA  1 
ATOM   5324  C  C   . GLU B 1 299 ? -63.580 30.810  44.339  1.00 53.67  ? 278 GLU B C   1 
ATOM   5325  O  O   . GLU B 1 299 ? -62.894 30.709  45.360  1.00 56.41  ? 278 GLU B O   1 
ATOM   5326  C  CB  . GLU B 1 299 ? -65.252 32.566  44.969  1.00 61.46  ? 278 GLU B CB  1 
ATOM   5327  C  CG  . GLU B 1 299 ? -65.987 33.851  44.591  1.00 60.96  ? 278 GLU B CG  1 
ATOM   5328  C  CD  . GLU B 1 299 ? -65.131 35.092  44.808  1.00 70.49  ? 278 GLU B CD  1 
ATOM   5329  O  OE1 . GLU B 1 299 ? -64.358 35.106  45.790  1.00 71.20  ? 278 GLU B OE1 1 
ATOM   5330  O  OE2 . GLU B 1 299 ? -65.230 36.048  44.000  1.00 78.11  ? 278 GLU B OE2 1 
ATOM   5331  N  N   . THR B 1 300 ? -63.813 29.772  43.528  1.00 37.59  ? 279 THR B N   1 
ATOM   5332  C  CA  . THR B 1 300 ? -63.562 28.399  43.950  1.00 35.88  ? 279 THR B CA  1 
ATOM   5333  C  C   . THR B 1 300 ? -62.294 27.792  43.366  1.00 41.13  ? 279 THR B C   1 
ATOM   5334  O  O   . THR B 1 300 ? -61.818 26.785  43.892  1.00 36.24  ? 279 THR B O   1 
ATOM   5335  C  CB  . THR B 1 300 ? -64.739 27.506  43.554  1.00 43.05  ? 279 THR B CB  1 
ATOM   5336  O  OG1 . THR B 1 300 ? -64.816 27.450  42.124  1.00 33.55  ? 279 THR B OG1 1 
ATOM   5337  C  CG2 . THR B 1 300 ? -66.041 28.083  44.084  1.00 45.81  ? 279 THR B CG2 1 
ATOM   5338  N  N   . GLY B 1 301 ? -61.741 28.351  42.294  1.00 31.84  ? 280 GLY B N   1 
ATOM   5339  C  CA  . GLY B 1 301 ? -60.667 27.660  41.605  1.00 33.59  ? 280 GLY B CA  1 
ATOM   5340  C  C   . GLY B 1 301 ? -61.095 26.471  40.771  1.00 30.20  ? 280 GLY B C   1 
ATOM   5341  O  O   . GLY B 1 301 ? -60.241 25.889  40.073  1.00 30.44  ? 280 GLY B O   1 
ATOM   5342  N  N   . ARG B 1 302 ? -62.388 26.111  40.783  1.00 24.82  ? 281 ARG B N   1 
ATOM   5343  C  CA  . ARG B 1 302 ? -62.850 24.923  40.067  1.00 32.55  ? 281 ARG B CA  1 
ATOM   5344  C  C   . ARG B 1 302 ? -62.696 25.066  38.557  1.00 29.95  ? 281 ARG B C   1 
ATOM   5345  O  O   . ARG B 1 302 ? -62.346 24.093  37.874  1.00 25.02  ? 281 ARG B O   1 
ATOM   5346  C  CB  . ARG B 1 302 ? -64.315 24.637  40.397  1.00 32.03  ? 281 ARG B CB  1 
ATOM   5347  C  CG  . ARG B 1 302 ? -64.540 24.002  41.758  1.00 37.11  ? 281 ARG B CG  1 
ATOM   5348  C  CD  . ARG B 1 302 ? -65.974 23.466  41.847  1.00 62.92  ? 281 ARG B CD  1 
ATOM   5349  N  NE  . ARG B 1 302 ? -66.068 22.319  42.743  1.00 87.91  ? 281 ARG B NE  1 
ATOM   5350  C  CZ  . ARG B 1 302 ? -65.783 21.072  42.395  1.00 78.71  ? 281 ARG B CZ  1 
ATOM   5351  N  NH1 . ARG B 1 302 ? -65.387 20.769  41.167  1.00 62.26  ? 281 ARG B NH1 1 
ATOM   5352  N  NH2 . ARG B 1 302 ? -65.899 20.103  43.301  1.00 77.55  ? 281 ARG B NH2 1 
ATOM   5353  N  N   . GLU B 1 303 ? -63.072 26.225  38.008  1.00 25.67  ? 282 GLU B N   1 
ATOM   5354  C  CA  . GLU B 1 303 ? -62.989 26.433  36.567  1.00 23.12  ? 282 GLU B CA  1 
ATOM   5355  C  C   . GLU B 1 303 ? -61.537 26.389  36.104  1.00 23.46  ? 282 GLU B C   1 
ATOM   5356  O  O   . GLU B 1 303 ? -61.240 25.830  35.042  1.00 23.77  ? 282 GLU B O   1 
ATOM   5357  C  CB  . GLU B 1 303 ? -63.623 27.777  36.186  1.00 23.28  ? 282 GLU B CB  1 
ATOM   5358  C  CG  . GLU B 1 303 ? -65.137 27.838  36.485  1.00 25.67  ? 282 GLU B CG  1 
ATOM   5359  C  CD  . GLU B 1 303 ? -65.415 28.164  37.964  1.00 32.72  ? 282 GLU B CD  1 
ATOM   5360  O  OE1 . GLU B 1 303 ? -64.452 28.385  38.729  1.00 27.32  ? 282 GLU B OE1 1 
ATOM   5361  O  OE2 . GLU B 1 303 ? -66.589 28.190  38.353  1.00 33.70  ? 282 GLU B OE2 1 
ATOM   5362  N  N   . ALA B 1 304 ? -60.624 26.983  36.884  1.00 23.08  ? 283 ALA B N   1 
ATOM   5363  C  CA  . ALA B 1 304 ? -59.213 26.953  36.508  1.00 28.88  ? 283 ALA B CA  1 
ATOM   5364  C  C   . ALA B 1 304 ? -58.685 25.523  36.506  1.00 26.74  ? 283 ALA B C   1 
ATOM   5365  O  O   . ALA B 1 304 ? -57.881 25.164  35.643  1.00 24.58  ? 283 ALA B O   1 
ATOM   5366  C  CB  . ALA B 1 304 ? -58.360 27.831  37.448  1.00 25.01  ? 283 ALA B CB  1 
ATOM   5367  N  N   . PHE B 1 305 ? -59.102 24.712  37.486  1.00 21.85  ? 284 PHE B N   1 
ATOM   5368  C  CA  . PHE B 1 305 ? -58.681 23.309  37.538  1.00 25.68  ? 284 PHE B CA  1 
ATOM   5369  C  C   . PHE B 1 305 ? -59.220 22.536  36.336  1.00 28.36  ? 284 PHE B C   1 
ATOM   5370  O  O   . PHE B 1 305 ? -58.466 21.832  35.658  1.00 23.14  ? 284 PHE B O   1 
ATOM   5371  C  CB  . PHE B 1 305 ? -59.128 22.677  38.870  1.00 28.24  ? 284 PHE B CB  1 
ATOM   5372  C  CG  . PHE B 1 305 ? -59.019 21.150  38.927  1.00 31.32  ? 284 PHE B CG  1 
ATOM   5373  C  CD1 . PHE B 1 305 ? -60.101 20.352  38.538  1.00 44.53  ? 284 PHE B CD1 1 
ATOM   5374  C  CD2 . PHE B 1 305 ? -57.871 20.529  39.371  1.00 33.27  ? 284 PHE B CD2 1 
ATOM   5375  C  CE1 . PHE B 1 305 ? -60.032 18.945  38.589  1.00 43.60  ? 284 PHE B CE1 1 
ATOM   5376  C  CE2 . PHE B 1 305 ? -57.792 19.120  39.449  1.00 27.77  ? 284 PHE B CE2 1 
ATOM   5377  C  CZ  . PHE B 1 305 ? -58.868 18.334  39.052  1.00 40.81  ? 284 PHE B CZ  1 
ATOM   5378  N  N   . ALA B 1 306 ? -60.511 22.702  36.020  1.00 24.84  ? 285 ALA B N   1 
ATOM   5379  C  CA  . ALA B 1 306 ? -61.082 22.026  34.864  1.00 23.04  ? 285 ALA B CA  1 
ATOM   5380  C  C   . ALA B 1 306 ? -60.418 22.478  33.575  1.00 20.44  ? 285 ALA B C   1 
ATOM   5381  O  O   . ALA B 1 306 ? -60.236 21.672  32.656  1.00 22.11  ? 285 ALA B O   1 
ATOM   5382  C  CB  . ALA B 1 306 ? -62.584 22.285  34.784  1.00 21.53  ? 285 ALA B CB  1 
ATOM   5383  N  N   . PHE B 1 307 ? -60.095 23.773  33.475  1.00 20.34  ? 286 PHE B N   1 
ATOM   5384  C  CA  . PHE B 1 307 ? -59.439 24.295  32.278  1.00 21.05  ? 286 PHE B CA  1 
ATOM   5385  C  C   . PHE B 1 307 ? -58.061 23.677  32.128  1.00 19.87  ? 286 PHE B C   1 
ATOM   5386  O  O   . PHE B 1 307 ? -57.683 23.214  31.037  1.00 20.43  ? 286 PHE B O   1 
ATOM   5387  C  CB  . PHE B 1 307 ? -59.356 25.834  32.380  1.00 20.21  ? 286 PHE B CB  1 
ATOM   5388  C  CG  . PHE B 1 307 ? -59.033 26.538  31.085  1.00 21.47  ? 286 PHE B CG  1 
ATOM   5389  C  CD1 . PHE B 1 307 ? -57.705 26.719  30.684  1.00 18.54  ? 286 PHE B CD1 1 
ATOM   5390  C  CD2 . PHE B 1 307 ? -60.069 27.081  30.302  1.00 22.39  ? 286 PHE B CD2 1 
ATOM   5391  C  CE1 . PHE B 1 307 ? -57.413 27.414  29.508  1.00 20.45  ? 286 PHE B CE1 1 
ATOM   5392  C  CE2 . PHE B 1 307 ? -59.787 27.773  29.142  1.00 18.98  ? 286 PHE B CE2 1 
ATOM   5393  C  CZ  . PHE B 1 307 ? -58.435 27.923  28.744  1.00 18.81  ? 286 PHE B CZ  1 
ATOM   5394  N  N   . ALA B 1 308 ? -57.300 23.652  33.232  1.00 19.79  ? 287 ALA B N   1 
ATOM   5395  C  CA  . ALA B 1 308 ? -55.984 23.012  33.221  1.00 26.37  ? 287 ALA B CA  1 
ATOM   5396  C  C   . ALA B 1 308 ? -56.068 21.545  32.782  1.00 26.80  ? 287 ALA B C   1 
ATOM   5397  O  O   . ALA B 1 308 ? -55.224 21.070  31.999  1.00 21.43  ? 287 ALA B O   1 
ATOM   5398  C  CB  . ALA B 1 308 ? -55.333 23.130  34.602  1.00 21.15  ? 287 ALA B CB  1 
ATOM   5399  N  N   . GLN B 1 309 ? -57.062 20.802  33.278  1.00 18.83  ? 288 GLN B N   1 
ATOM   5400  C  CA  . GLN B 1 309 ? -57.178 19.396  32.885  1.00 20.66  ? 288 GLN B CA  1 
ATOM   5401  C  C   . GLN B 1 309 ? -57.508 19.250  31.404  1.00 22.24  ? 288 GLN B C   1 
ATOM   5402  O  O   . GLN B 1 309 ? -56.971 18.364  30.714  1.00 21.65  ? 288 GLN B O   1 
ATOM   5403  C  CB  . GLN B 1 309 ? -58.258 18.699  33.742  1.00 23.19  ? 288 GLN B CB  1 
ATOM   5404  C  CG  . GLN B 1 309 ? -57.876 18.636  35.208  1.00 28.39  ? 288 GLN B CG  1 
ATOM   5405  C  CD  . GLN B 1 309 ? -56.847 17.557  35.503  1.00 25.74  ? 288 GLN B CD  1 
ATOM   5406  O  OE1 . GLN B 1 309 ? -55.876 17.386  34.765  1.00 24.15  ? 288 GLN B OE1 1 
ATOM   5407  N  NE2 . GLN B 1 309 ? -57.064 16.819  36.576  1.00 25.35  ? 288 GLN B NE2 1 
ATOM   5408  N  N   . GLU B 1 310 ? -58.409 20.093  30.894  1.00 19.06  ? 289 GLU B N   1 
ATOM   5409  C  CA  . GLU B 1 310 ? -58.728 19.988  29.472  1.00 23.31  ? 289 GLU B CA  1 
ATOM   5410  C  C   . GLU B 1 310 ? -57.584 20.504  28.597  1.00 25.10  ? 289 GLU B C   1 
ATOM   5411  O  O   . GLU B 1 310 ? -57.476 20.084  27.451  1.00 23.19  ? 289 GLU B O   1 
ATOM   5412  C  CB  . GLU B 1 310 ? -60.053 20.696  29.170  1.00 24.76  ? 289 GLU B CB  1 
ATOM   5413  C  CG  . GLU B 1 310 ? -60.525 20.696  27.712  1.00 23.63  ? 289 GLU B CG  1 
ATOM   5414  C  CD  . GLU B 1 310 ? -60.999 19.345  27.208  1.00 30.07  ? 289 GLU B CD  1 
ATOM   5415  O  OE1 . GLU B 1 310 ? -60.613 18.287  27.775  1.00 32.83  ? 289 GLU B OE1 1 
ATOM   5416  O  OE2 . GLU B 1 310 ? -61.816 19.335  26.260  1.00 23.43  ? 289 GLU B OE2 1 
ATOM   5417  N  N   . VAL B 1 311 ? -56.669 21.336  29.118  1.00 19.20  ? 290 VAL B N   1 
ATOM   5418  C  CA  . VAL B 1 311 ? -55.441 21.581  28.352  1.00 17.35  ? 290 VAL B CA  1 
ATOM   5419  C  C   . VAL B 1 311 ? -54.596 20.303  28.265  1.00 20.65  ? 290 VAL B C   1 
ATOM   5420  O  O   . VAL B 1 311 ? -54.008 20.009  27.224  1.00 21.39  ? 290 VAL B O   1 
ATOM   5421  C  CB  . VAL B 1 311 ? -54.645 22.746  28.966  1.00 18.74  ? 290 VAL B CB  1 
ATOM   5422  C  CG1 . VAL B 1 311 ? -53.168 22.797  28.426  1.00 18.18  ? 290 VAL B CG1 1 
ATOM   5423  C  CG2 . VAL B 1 311 ? -55.397 24.074  28.687  1.00 17.11  ? 290 VAL B CG2 1 
ATOM   5424  N  N   . ARG B 1 312 ? -54.506 19.538  29.357  1.00 19.25  ? 291 ARG B N   1 
ATOM   5425  C  CA  . ARG B 1 312 ? -53.735 18.285  29.334  1.00 20.55  ? 291 ARG B CA  1 
ATOM   5426  C  C   . ARG B 1 312 ? -54.380 17.243  28.438  1.00 23.75  ? 291 ARG B C   1 
ATOM   5427  O  O   . ARG B 1 312 ? -53.676 16.431  27.815  1.00 21.17  ? 291 ARG B O   1 
ATOM   5428  C  CB  . ARG B 1 312 ? -53.598 17.721  30.765  1.00 21.91  ? 291 ARG B CB  1 
ATOM   5429  C  CG  . ARG B 1 312 ? -52.735 18.624  31.657  1.00 22.21  ? 291 ARG B CG  1 
ATOM   5430  C  CD  . ARG B 1 312 ? -52.104 17.850  32.847  1.00 24.46  ? 291 ARG B CD  1 
ATOM   5431  N  NE  . ARG B 1 312 ? -53.108 17.125  33.612  1.00 21.49  ? 291 ARG B NE  1 
ATOM   5432  C  CZ  . ARG B 1 312 ? -52.916 15.922  34.135  1.00 24.33  ? 291 ARG B CZ  1 
ATOM   5433  N  NH1 . ARG B 1 312 ? -51.754 15.281  34.010  1.00 24.81  ? 291 ARG B NH1 1 
ATOM   5434  N  NH2 . ARG B 1 312 ? -53.907 15.339  34.801  1.00 25.87  ? 291 ARG B NH2 1 
ATOM   5435  N  N   . ARG B 1 313 ? -55.709 17.225  28.360  1.00 21.23  ? 292 ARG B N   1 
ATOM   5436  C  CA  . ARG B 1 313 ? -56.335 16.257  27.452  1.00 19.16  ? 292 ARG B CA  1 
ATOM   5437  C  C   . ARG B 1 313 ? -56.176 16.657  25.978  1.00 28.00  ? 292 ARG B C   1 
ATOM   5438  O  O   . ARG B 1 313 ? -55.897 15.802  25.125  1.00 27.97  ? 292 ARG B O   1 
ATOM   5439  C  CB  . ARG B 1 313 ? -57.817 16.074  27.787  1.00 22.40  ? 292 ARG B CB  1 
ATOM   5440  C  CG  . ARG B 1 313 ? -58.408 14.941  26.866  1.00 27.10  ? 292 ARG B CG  1 
ATOM   5441  C  CD  . ARG B 1 313 ? -59.852 15.069  26.634  1.00 26.15  ? 292 ARG B CD  1 
ATOM   5442  N  NE  . ARG B 1 313 ? -60.190 16.283  25.900  1.00 23.87  ? 292 ARG B NE  1 
ATOM   5443  C  CZ  . ARG B 1 313 ? -60.458 16.332  24.598  1.00 24.49  ? 292 ARG B CZ  1 
ATOM   5444  N  NH1 . ARG B 1 313 ? -60.259 15.284  23.799  1.00 23.31  ? 292 ARG B NH1 1 
ATOM   5445  N  NH2 . ARG B 1 313 ? -60.966 17.454  24.085  1.00 21.15  ? 292 ARG B NH2 1 
ATOM   5446  N  N   . PHE B 1 314 ? -56.329 17.944  25.655  1.00 20.68  ? 293 PHE B N   1 
ATOM   5447  C  CA  . PHE B 1 314 ? -56.537 18.389  24.284  1.00 21.61  ? 293 PHE B CA  1 
ATOM   5448  C  C   . PHE B 1 314 ? -55.239 18.596  23.516  1.00 23.18  ? 293 PHE B C   1 
ATOM   5449  O  O   . PHE B 1 314 ? -55.165 18.244  22.333  1.00 23.24  ? 293 PHE B O   1 
ATOM   5450  C  CB  . PHE B 1 314 ? -57.353 19.693  24.272  1.00 20.98  ? 293 PHE B CB  1 
ATOM   5451  C  CG  . PHE B 1 314 ? -57.668 20.196  22.888  1.00 23.79  ? 293 PHE B CG  1 
ATOM   5452  C  CD1 . PHE B 1 314 ? -58.784 19.731  22.206  1.00 24.94  ? 293 PHE B CD1 1 
ATOM   5453  C  CD2 . PHE B 1 314 ? -56.846 21.118  22.274  1.00 22.19  ? 293 PHE B CD2 1 
ATOM   5454  C  CE1 . PHE B 1 314 ? -59.081 20.215  20.936  1.00 27.25  ? 293 PHE B CE1 1 
ATOM   5455  C  CE2 . PHE B 1 314 ? -57.131 21.602  21.005  1.00 33.63  ? 293 PHE B CE2 1 
ATOM   5456  C  CZ  . PHE B 1 314 ? -58.243 21.143  20.333  1.00 32.66  ? 293 PHE B CZ  1 
ATOM   5457  N  N   . TYR B 1 315 ? -54.217 19.172  24.154  1.00 20.64  ? 294 TYR B N   1 
ATOM   5458  C  CA  . TYR B 1 315 ? -53.031 19.625  23.444  1.00 18.14  ? 294 TYR B CA  1 
ATOM   5459  C  C   . TYR B 1 315 ? -51.957 18.544  23.439  1.00 20.06  ? 294 TYR B C   1 
ATOM   5460  O  O   . TYR B 1 315 ? -51.855 17.750  24.368  1.00 24.50  ? 294 TYR B O   1 
ATOM   5461  C  CB  . TYR B 1 315 ? -52.474 20.907  24.072  1.00 20.35  ? 294 TYR B CB  1 
ATOM   5462  C  CG  . TYR B 1 315 ? -53.382 22.094  23.774  1.00 23.03  ? 294 TYR B CG  1 
ATOM   5463  C  CD1 . TYR B 1 315 ? -53.322 22.724  22.553  1.00 19.61  ? 294 TYR B CD1 1 
ATOM   5464  C  CD2 . TYR B 1 315 ? -54.327 22.535  24.702  1.00 17.86  ? 294 TYR B CD2 1 
ATOM   5465  C  CE1 . TYR B 1 315 ? -54.158 23.803  22.224  1.00 22.86  ? 294 TYR B CE1 1 
ATOM   5466  C  CE2 . TYR B 1 315 ? -55.192 23.627  24.378  1.00 21.06  ? 294 TYR B CE2 1 
ATOM   5467  C  CZ  . TYR B 1 315 ? -55.088 24.237  23.145  1.00 23.08  ? 294 TYR B CZ  1 
ATOM   5468  O  OH  . TYR B 1 315 ? -55.904 25.305  22.792  1.00 25.96  ? 294 TYR B OH  1 
ATOM   5469  N  N   . PRO B 1 316 ? -51.145 18.501  22.389  1.00 20.87  ? 295 PRO B N   1 
ATOM   5470  C  CA  . PRO B 1 316 ? -50.177 17.408  22.259  1.00 21.30  ? 295 PRO B CA  1 
ATOM   5471  C  C   . PRO B 1 316 ? -48.962 17.659  23.142  1.00 23.61  ? 295 PRO B C   1 
ATOM   5472  O  O   . PRO B 1 316 ? -48.378 18.741  23.131  1.00 23.56  ? 295 PRO B O   1 
ATOM   5473  C  CB  . PRO B 1 316 ? -49.813 17.432  20.764  1.00 21.26  ? 295 PRO B CB  1 
ATOM   5474  C  CG  . PRO B 1 316 ? -49.920 18.892  20.375  1.00 25.30  ? 295 PRO B CG  1 
ATOM   5475  C  CD  . PRO B 1 316 ? -51.155 19.396  21.216  1.00 20.95  ? 295 PRO B CD  1 
ATOM   5476  N  N   . PHE B 1 317 ? -48.588 16.648  23.922  1.00 22.05  ? 296 PHE B N   1 
ATOM   5477  C  CA  . PHE B 1 317 ? -47.369 16.732  24.704  1.00 21.36  ? 296 PHE B CA  1 
ATOM   5478  C  C   . PHE B 1 317 ? -46.672 15.387  24.528  1.00 19.95  ? 296 PHE B C   1 
ATOM   5479  O  O   . PHE B 1 317 ? -45.684 15.266  23.785  1.00 21.25  ? 296 PHE B O   1 
ATOM   5480  C  CB  . PHE B 1 317 ? -47.707 17.056  26.175  1.00 21.68  ? 296 PHE B CB  1 
ATOM   5481  C  CG  . PHE B 1 317 ? -46.514 17.497  27.010  1.00 22.76  ? 296 PHE B CG  1 
ATOM   5482  C  CD1 . PHE B 1 317 ? -45.297 16.851  26.925  1.00 28.47  ? 296 PHE B CD1 1 
ATOM   5483  C  CD2 . PHE B 1 317 ? -46.630 18.585  27.865  1.00 24.33  ? 296 PHE B CD2 1 
ATOM   5484  C  CE1 . PHE B 1 317 ? -44.199 17.277  27.672  1.00 28.26  ? 296 PHE B CE1 1 
ATOM   5485  C  CE2 . PHE B 1 317 ? -45.532 19.010  28.632  1.00 27.56  ? 296 PHE B CE2 1 
ATOM   5486  C  CZ  . PHE B 1 317 ? -44.321 18.366  28.515  1.00 24.74  ? 296 PHE B CZ  1 
ATOM   5487  N  N   . VAL B 1 318 ? -47.179 14.350  25.189  1.00 21.39  ? 297 VAL B N   1 
ATOM   5488  C  CA  . VAL B 1 318 ? -46.630 13.019  24.951  1.00 24.79  ? 297 VAL B CA  1 
ATOM   5489  C  C   . VAL B 1 318 ? -47.248 12.466  23.672  1.00 24.05  ? 297 VAL B C   1 
ATOM   5490  O  O   . VAL B 1 318 ? -48.467 12.301  23.609  1.00 23.89  ? 297 VAL B O   1 
ATOM   5491  C  CB  . VAL B 1 318 ? -46.910 12.071  26.123  1.00 22.27  ? 297 VAL B CB  1 
ATOM   5492  C  CG1 . VAL B 1 318 ? -46.259 10.707  25.825  1.00 23.77  ? 297 VAL B CG1 1 
ATOM   5493  C  CG2 . VAL B 1 318 ? -46.405 12.687  27.451  1.00 20.64  ? 297 VAL B CG2 1 
ATOM   5494  N  N   . PRO B 1 319 ? -46.465 12.147  22.642  1.00 22.84  ? 298 PRO B N   1 
ATOM   5495  C  CA  . PRO B 1 319 ? -47.090 11.611  21.427  1.00 26.98  ? 298 PRO B CA  1 
ATOM   5496  C  C   . PRO B 1 319 ? -47.545 10.164  21.609  1.00 33.31  ? 298 PRO B C   1 
ATOM   5497  O  O   . PRO B 1 319 ? -48.651 9.762   21.192  1.00 25.25  ? 298 PRO B O   1 
ATOM   5498  C  CB  . PRO B 1 319 ? -45.961 11.735  20.387  1.00 25.93  ? 298 PRO B CB  1 
ATOM   5499  C  CG  . PRO B 1 319 ? -44.674 11.603  21.176  1.00 24.96  ? 298 PRO B CG  1 
ATOM   5500  C  CD  . PRO B 1 319 ? -44.994 12.245  22.544  1.00 21.52  ? 298 PRO B CD  1 
ATOM   5501  N  N   . MET B 1 320 ? -46.708 9.385   22.276  1.00 23.89  ? 299 MET B N   1 
ATOM   5502  C  CA  . MET B 1 320 ? -46.805 7.935   22.361  1.00 25.41  ? 299 MET B CA  1 
ATOM   5503  C  C   . MET B 1 320 ? -45.713 7.525   23.337  1.00 26.60  ? 299 MET B C   1 
ATOM   5504  O  O   . MET B 1 320 ? -44.844 8.338   23.682  1.00 22.89  ? 299 MET B O   1 
ATOM   5505  C  CB  . MET B 1 320 ? -46.598 7.305   20.973  1.00 21.15  ? 299 MET B CB  1 
ATOM   5506  C  CG  . MET B 1 320 ? -45.183 7.354   20.489  1.00 24.88  ? 299 MET B CG  1 
ATOM   5507  S  SD  . MET B 1 320 ? -45.093 6.967   18.728  1.00 34.14  ? 299 MET B SD  1 
ATOM   5508  C  CE  . MET B 1 320 ? -45.300 8.602   17.984  1.00 34.84  ? 299 MET B CE  1 
ATOM   5509  N  N   . PHE B 1 321 ? -45.750 6.267   23.781  1.00 25.69  ? 300 PHE B N   1 
ATOM   5510  C  CA  . PHE B 1 321 ? -44.744 5.821   24.733  1.00 23.79  ? 300 PHE B CA  1 
ATOM   5511  C  C   . PHE B 1 321 ? -44.508 4.338   24.526  1.00 23.49  ? 300 PHE B C   1 
ATOM   5512  O  O   . PHE B 1 321 ? -45.446 3.605   24.175  1.00 20.60  ? 300 PHE B O   1 
ATOM   5513  C  CB  . PHE B 1 321 ? -45.177 6.103   26.185  1.00 21.20  ? 300 PHE B CB  1 
ATOM   5514  C  CG  . PHE B 1 321 ? -44.033 6.468   27.083  1.00 23.37  ? 300 PHE B CG  1 
ATOM   5515  C  CD1 . PHE B 1 321 ? -43.437 7.728   27.003  1.00 21.51  ? 300 PHE B CD1 1 
ATOM   5516  C  CD2 . PHE B 1 321 ? -43.537 5.544   28.016  1.00 26.50  ? 300 PHE B CD2 1 
ATOM   5517  C  CE1 . PHE B 1 321 ? -42.361 8.055   27.845  1.00 24.12  ? 300 PHE B CE1 1 
ATOM   5518  C  CE2 . PHE B 1 321 ? -42.461 5.871   28.832  1.00 23.13  ? 300 PHE B CE2 1 
ATOM   5519  C  CZ  . PHE B 1 321 ? -41.877 7.128   28.740  1.00 23.47  ? 300 PHE B CZ  1 
ATOM   5520  N  N   . PRO B 1 322 ? -43.263 3.852   24.742  1.00 22.00  ? 301 PRO B N   1 
ATOM   5521  C  CA  . PRO B 1 322 ? -42.947 2.470   24.360  1.00 20.71  ? 301 PRO B CA  1 
ATOM   5522  C  C   . PRO B 1 322 ? -42.692 1.522   25.525  1.00 22.39  ? 301 PRO B C   1 
ATOM   5523  O  O   . PRO B 1 322 ? -42.263 1.924   26.619  1.00 20.59  ? 301 PRO B O   1 
ATOM   5524  C  CB  . PRO B 1 322 ? -41.677 2.637   23.525  1.00 22.91  ? 301 PRO B CB  1 
ATOM   5525  C  CG  . PRO B 1 322 ? -40.907 3.745   24.305  1.00 25.85  ? 301 PRO B CG  1 
ATOM   5526  C  CD  . PRO B 1 322 ? -42.046 4.687   24.838  1.00 23.73  ? 301 PRO B CD  1 
ATOM   5527  N  N   . ALA B 1 323 ? -43.034 0.259   25.277  1.00 22.15  ? 302 ALA B N   1 
ATOM   5528  C  CA  . ALA B 1 323 ? -42.662 -0.869  26.114  1.00 20.97  ? 302 ALA B CA  1 
ATOM   5529  C  C   . ALA B 1 323 ? -42.188 -1.995  25.193  1.00 23.27  ? 302 ALA B C   1 
ATOM   5530  O  O   . ALA B 1 323 ? -42.292 -1.902  23.972  1.00 23.90  ? 302 ALA B O   1 
ATOM   5531  C  CB  . ALA B 1 323 ? -43.831 -1.321  26.994  1.00 17.85  ? 302 ALA B CB  1 
ATOM   5532  N  N   . LYS B 1 324 ? -41.642 -3.063  25.781  1.00 22.07  ? 303 LYS B N   1 
ATOM   5533  C  CA  . LYS B 1 324 ? -41.185 -4.209  24.994  1.00 23.03  ? 303 LYS B CA  1 
ATOM   5534  C  C   . LYS B 1 324 ? -41.809 -5.475  25.565  1.00 22.25  ? 303 LYS B C   1 
ATOM   5535  O  O   . LYS B 1 324 ? -41.931 -5.615  26.778  1.00 20.94  ? 303 LYS B O   1 
ATOM   5536  C  CB  . LYS B 1 324 ? -39.658 -4.337  25.000  1.00 28.75  ? 303 LYS B CB  1 
ATOM   5537  C  CG  . LYS B 1 324 ? -38.933 -3.367  24.021  1.00 30.64  ? 303 LYS B CG  1 
ATOM   5538  C  CD  . LYS B 1 324 ? -37.400 -3.363  24.240  1.00 36.56  ? 303 LYS B CD  1 
ATOM   5539  C  CE  . LYS B 1 324 ? -36.730 -4.610  23.697  1.00 48.91  ? 303 LYS B CE  1 
ATOM   5540  N  NZ  . LYS B 1 324 ? -36.530 -4.540  22.219  1.00 39.38  ? 303 LYS B NZ  1 
ATOM   5541  N  N   . ALA B 1 325 ? -42.231 -6.384  24.681  1.00 21.84  ? 304 ALA B N   1 
ATOM   5542  C  CA  . ALA B 1 325 ? -42.849 -7.633  25.119  1.00 23.55  ? 304 ALA B CA  1 
ATOM   5543  C  C   . ALA B 1 325 ? -41.805 -8.562  25.741  1.00 25.04  ? 304 ALA B C   1 
ATOM   5544  O  O   . ALA B 1 325 ? -40.735 -8.786  25.169  1.00 25.49  ? 304 ALA B O   1 
ATOM   5545  C  CB  . ALA B 1 325 ? -43.526 -8.340  23.928  1.00 24.17  ? 304 ALA B CB  1 
ATOM   5546  N  N   . THR B 1 326 ? -42.115 -9.100  26.908  1.00 20.75  ? 305 THR B N   1 
ATOM   5547  C  CA  . THR B 1 326 ? -41.214 -10.018 27.605  1.00 24.10  ? 305 THR B CA  1 
ATOM   5548  C  C   . THR B 1 326 ? -41.379 -11.457 27.154  1.00 26.03  ? 305 THR B C   1 
ATOM   5549  O  O   . THR B 1 326 ? -40.593 -12.322 27.566  1.00 27.42  ? 305 THR B O   1 
ATOM   5550  C  CB  . THR B 1 326 ? -41.467 -9.982  29.114  1.00 29.56  ? 305 THR B CB  1 
ATOM   5551  O  OG1 . THR B 1 326 ? -42.779 -10.474 29.354  1.00 25.63  ? 305 THR B OG1 1 
ATOM   5552  C  CG2 . THR B 1 326 ? -41.371 -8.541  29.671  1.00 31.14  ? 305 THR B CG2 1 
ATOM   5553  N  N   . LYS B 1 327 ? -42.429 -11.747 26.400  1.00 26.24  ? 306 LYS B N   1 
ATOM   5554  C  CA  . LYS B 1 327 ? -42.695 -13.110 25.950  1.00 27.46  ? 306 LYS B CA  1 
ATOM   5555  C  C   . LYS B 1 327 ? -43.631 -13.001 24.766  1.00 29.34  ? 306 LYS B C   1 
ATOM   5556  O  O   . LYS B 1 327 ? -44.225 -11.953 24.534  1.00 25.25  ? 306 LYS B O   1 
ATOM   5557  C  CB  . LYS B 1 327 ? -43.327 -13.956 27.055  1.00 25.44  ? 306 LYS B CB  1 
ATOM   5558  C  CG  . LYS B 1 327 ? -44.720 -13.482 27.398  1.00 29.60  ? 306 LYS B CG  1 
ATOM   5559  C  CD  . LYS B 1 327 ? -45.348 -14.316 28.498  1.00 38.20  ? 306 LYS B CD  1 
ATOM   5560  C  CE  . LYS B 1 327 ? -44.684 -14.087 29.840  1.00 39.89  ? 306 LYS B CE  1 
ATOM   5561  N  NZ  . LYS B 1 327 ? -45.389 -14.882 30.909  1.00 60.74  ? 306 LYS B NZ  1 
ATOM   5562  N  N   . ASP B 1 328 ? -43.791 -14.102 24.030  1.00 22.54  ? 307 ASP B N   1 
ATOM   5563  C  CA  . ASP B 1 328 ? -44.767 -14.098 22.941  1.00 21.35  ? 307 ASP B CA  1 
ATOM   5564  C  C   . ASP B 1 328 ? -46.172 -14.031 23.526  1.00 30.42  ? 307 ASP B C   1 
ATOM   5565  O  O   . ASP B 1 328 ? -46.470 -14.707 24.504  1.00 25.63  ? 307 ASP B O   1 
ATOM   5566  C  CB  . ASP B 1 328 ? -44.617 -15.358 22.091  1.00 25.56  ? 307 ASP B CB  1 
ATOM   5567  C  CG  . ASP B 1 328 ? -43.258 -15.430 21.373  1.00 28.92  ? 307 ASP B CG  1 
ATOM   5568  O  OD1 . ASP B 1 328 ? -42.745 -14.390 20.940  1.00 25.13  ? 307 ASP B OD1 1 
ATOM   5569  O  OD2 . ASP B 1 328 ? -42.709 -16.540 21.230  1.00 25.87  ? 307 ASP B OD2 1 
ATOM   5570  N  N   . THR B 1 329 ? -47.030 -13.198 22.949  1.00 24.18  ? 308 THR B N   1 
ATOM   5571  C  CA  . THR B 1 329 ? -48.401 -13.124 23.451  1.00 24.67  ? 308 THR B CA  1 
ATOM   5572  C  C   . THR B 1 329 ? -49.265 -12.642 22.289  1.00 26.81  ? 308 THR B C   1 
ATOM   5573  O  O   . THR B 1 329 ? -48.847 -12.692 21.127  1.00 26.46  ? 308 THR B O   1 
ATOM   5574  C  CB  . THR B 1 329 ? -48.472 -12.226 24.718  1.00 29.46  ? 308 THR B CB  1 
ATOM   5575  O  OG1 . THR B 1 329 ? -49.804 -12.237 25.278  1.00 32.92  ? 308 THR B OG1 1 
ATOM   5576  C  CG2 . THR B 1 329 ? -48.106 -10.789 24.379  1.00 30.52  ? 308 THR B CG2 1 
ATOM   5577  N  N   . GLU B 1 330 ? -50.461 -12.158 22.595  1.00 27.11  ? 309 GLU B N   1 
ATOM   5578  C  CA  . GLU B 1 330 ? -51.375 -11.751 21.546  1.00 27.22  ? 309 GLU B CA  1 
ATOM   5579  C  C   . GLU B 1 330 ? -52.206 -10.594 22.067  1.00 29.66  ? 309 GLU B C   1 
ATOM   5580  O  O   . GLU B 1 330 ? -52.477 -10.512 23.263  1.00 34.71  ? 309 GLU B O   1 
ATOM   5581  C  CB  . GLU B 1 330 ? -52.281 -12.922 21.139  1.00 32.41  ? 309 GLU B CB  1 
ATOM   5582  C  CG  . GLU B 1 330 ? -52.221 -13.256 19.680  1.00 41.70  ? 309 GLU B CG  1 
ATOM   5583  C  CD  . GLU B 1 330 ? -53.233 -14.325 19.310  1.00 53.46  ? 309 GLU B CD  1 
ATOM   5584  O  OE1 . GLU B 1 330 ? -54.378 -14.232 19.814  1.00 37.63  ? 309 GLU B OE1 1 
ATOM   5585  O  OE2 . GLU B 1 330 ? -52.879 -15.253 18.536  1.00 34.18  ? 309 GLU B OE2 1 
ATOM   5586  N  N   . PHE B 1 331 ? -52.626 -9.716  21.160  1.00 28.75  ? 310 PHE B N   1 
ATOM   5587  C  CA  . PHE B 1 331 ? -53.531 -8.627  21.525  1.00 27.20  ? 310 PHE B CA  1 
ATOM   5588  C  C   . PHE B 1 331 ? -54.584 -8.490  20.437  1.00 25.89  ? 310 PHE B C   1 
ATOM   5589  O  O   . PHE B 1 331 ? -54.246 -8.166  19.297  1.00 27.37  ? 310 PHE B O   1 
ATOM   5590  C  CB  . PHE B 1 331 ? -52.777 -7.307  21.701  1.00 25.06  ? 310 PHE B CB  1 
ATOM   5591  C  CG  . PHE B 1 331 ? -53.675 -6.134  22.054  1.00 28.08  ? 310 PHE B CG  1 
ATOM   5592  C  CD1 . PHE B 1 331 ? -54.347 -6.119  23.279  1.00 27.25  ? 310 PHE B CD1 1 
ATOM   5593  C  CD2 . PHE B 1 331 ? -53.816 -5.071  21.190  1.00 28.51  ? 310 PHE B CD2 1 
ATOM   5594  C  CE1 . PHE B 1 331 ? -55.176 -5.048  23.622  1.00 32.12  ? 310 PHE B CE1 1 
ATOM   5595  C  CE2 . PHE B 1 331 ? -54.665 -3.977  21.524  1.00 32.30  ? 310 PHE B CE2 1 
ATOM   5596  C  CZ  . PHE B 1 331 ? -55.320 -3.980  22.743  1.00 26.14  ? 310 PHE B CZ  1 
ATOM   5597  N  N   . GLU B 1 332 ? -55.854 -8.708  20.796  1.00 28.64  ? 311 GLU B N   1 
ATOM   5598  C  CA  . GLU B 1 332 ? -56.955 -8.569  19.836  1.00 33.20  ? 311 GLU B CA  1 
ATOM   5599  C  C   . GLU B 1 332 ? -56.692 -9.365  18.557  1.00 32.38  ? 311 GLU B C   1 
ATOM   5600  O  O   . GLU B 1 332 ? -56.868 -8.875  17.441  1.00 36.59  ? 311 GLU B O   1 
ATOM   5601  C  CB  . GLU B 1 332 ? -57.193 -7.095  19.545  1.00 28.94  ? 311 GLU B CB  1 
ATOM   5602  C  CG  . GLU B 1 332 ? -57.654 -6.405  20.832  1.00 39.06  ? 311 GLU B CG  1 
ATOM   5603  C  CD  . GLU B 1 332 ? -58.060 -4.964  20.640  1.00 54.40  ? 311 GLU B CD  1 
ATOM   5604  O  OE1 . GLU B 1 332 ? -57.801 -4.414  19.547  1.00 57.44  ? 311 GLU B OE1 1 
ATOM   5605  O  OE2 . GLU B 1 332 ? -58.643 -4.385  21.592  1.00 53.55  ? 311 GLU B OE2 1 
ATOM   5606  N  N   . GLY B 1 333 ? -56.217 -10.594 18.728  1.00 35.83  ? 312 GLY B N   1 
ATOM   5607  C  CA  . GLY B 1 333 ? -55.845 -11.432 17.611  1.00 34.11  ? 312 GLY B CA  1 
ATOM   5608  C  C   . GLY B 1 333 ? -54.482 -11.155 16.999  1.00 43.43  ? 312 GLY B C   1 
ATOM   5609  O  O   . GLY B 1 333 ? -53.992 -11.980 16.230  1.00 42.71  ? 312 GLY B O   1 
ATOM   5610  N  N   . CYS B 1 334 ? -53.857 -10.036 17.300  1.00 34.19  ? 313 CYS B N   1 
ATOM   5611  C  CA  . CYS B 1 334 ? -52.599 -9.701  16.636  1.00 30.18  ? 313 CYS B CA  1 
ATOM   5612  C  C   . CYS B 1 334 ? -51.441 -10.335 17.399  1.00 29.10  ? 313 CYS B C   1 
ATOM   5613  O  O   . CYS B 1 334 ? -51.372 -10.195 18.630  1.00 26.74  ? 313 CYS B O   1 
ATOM   5614  C  CB  . CYS B 1 334 ? -52.427 -8.183  16.569  1.00 41.50  ? 313 CYS B CB  1 
ATOM   5615  S  SG  . CYS B 1 334 ? -50.766 -7.528  16.134  1.00 47.47  ? 313 CYS B SG  1 
ATOM   5616  N  N   . PRO B 1 335 ? -50.556 -11.075 16.736  1.00 32.68  ? 314 PRO B N   1 
ATOM   5617  C  CA  . PRO B 1 335 ? -49.427 -11.685 17.452  1.00 28.11  ? 314 PRO B CA  1 
ATOM   5618  C  C   . PRO B 1 335 ? -48.484 -10.628 17.978  1.00 25.71  ? 314 PRO B C   1 
ATOM   5619  O  O   . PRO B 1 335 ? -48.198 -9.630  17.306  1.00 28.30  ? 314 PRO B O   1 
ATOM   5620  C  CB  . PRO B 1 335 ? -48.734 -12.539 16.377  1.00 28.14  ? 314 PRO B CB  1 
ATOM   5621  C  CG  . PRO B 1 335 ? -49.812 -12.788 15.346  1.00 41.22  ? 314 PRO B CG  1 
ATOM   5622  C  CD  . PRO B 1 335 ? -50.639 -11.528 15.330  1.00 32.47  ? 314 PRO B CD  1 
ATOM   5623  N  N   . ILE B 1 336 ? -47.986 -10.861 19.189  1.00 22.79  ? 315 ILE B N   1 
ATOM   5624  C  CA  . ILE B 1 336 ? -46.978 -10.002 19.805  1.00 26.30  ? 315 ILE B CA  1 
ATOM   5625  C  C   . ILE B 1 336 ? -45.755 -10.866 20.076  1.00 21.82  ? 315 ILE B C   1 
ATOM   5626  O  O   . ILE B 1 336 ? -45.832 -11.808 20.875  1.00 26.52  ? 315 ILE B O   1 
ATOM   5627  C  CB  . ILE B 1 336 ? -47.484 -9.364  21.106  1.00 24.48  ? 315 ILE B CB  1 
ATOM   5628  C  CG1 . ILE B 1 336 ? -48.781 -8.577  20.872  1.00 26.39  ? 315 ILE B CG1 1 
ATOM   5629  C  CG2 . ILE B 1 336 ? -46.393 -8.450  21.711  1.00 26.32  ? 315 ILE B CG2 1 
ATOM   5630  C  CD1 . ILE B 1 336 ? -48.601 -7.336  20.037  1.00 26.34  ? 315 ILE B CD1 1 
ATOM   5631  N  N   . HIS B 1 337 ? -44.635 -10.540 19.425  1.00 22.95  ? 316 HIS B N   1 
ATOM   5632  C  CA  . HIS B 1 337 ? -43.416 -11.340 19.532  1.00 24.08  ? 316 HIS B CA  1 
ATOM   5633  C  C   . HIS B 1 337 ? -42.488 -10.822 20.630  1.00 27.00  ? 316 HIS B C   1 
ATOM   5634  O  O   . HIS B 1 337 ? -42.275 -9.610  20.774  1.00 25.96  ? 316 HIS B O   1 
ATOM   5635  C  CB  . HIS B 1 337 ? -42.690 -11.342 18.187  1.00 24.80  ? 316 HIS B CB  1 
ATOM   5636  C  CG  . HIS B 1 337 ? -43.476 -11.983 17.098  1.00 31.67  ? 316 HIS B CG  1 
ATOM   5637  N  ND1 . HIS B 1 337 ? -43.604 -13.349 16.983  1.00 37.33  ? 316 HIS B ND1 1 
ATOM   5638  C  CD2 . HIS B 1 337 ? -44.183 -11.450 16.074  1.00 35.33  ? 316 HIS B CD2 1 
ATOM   5639  C  CE1 . HIS B 1 337 ? -44.370 -13.629 15.942  1.00 39.32  ? 316 HIS B CE1 1 
ATOM   5640  N  NE2 . HIS B 1 337 ? -44.721 -12.495 15.364  1.00 34.80  ? 316 HIS B NE2 1 
ATOM   5641  N  N   . GLN B 1 338 ? -41.906 -11.754 21.389  1.00 23.82  ? 317 GLN B N   1 
ATOM   5642  C  CA  . GLN B 1 338 ? -40.984 -11.369 22.450  1.00 19.62  ? 317 GLN B CA  1 
ATOM   5643  C  C   . GLN B 1 338 ? -39.934 -10.406 21.927  1.00 23.66  ? 317 GLN B C   1 
ATOM   5644  O  O   . GLN B 1 338 ? -39.328 -10.643 20.890  1.00 26.71  ? 317 GLN B O   1 
ATOM   5645  C  CB  . GLN B 1 338 ? -40.302 -12.608 23.015  1.00 19.31  ? 317 GLN B CB  1 
ATOM   5646  C  CG  . GLN B 1 338 ? -39.390 -12.292 24.198  1.00 19.35  ? 317 GLN B CG  1 
ATOM   5647  C  CD  . GLN B 1 338 ? -38.912 -13.578 24.909  1.00 24.02  ? 317 GLN B CD  1 
ATOM   5648  O  OE1 . GLN B 1 338 ? -39.329 -14.665 24.541  1.00 23.89  ? 317 GLN B OE1 1 
ATOM   5649  N  NE2 . GLN B 1 338 ? -38.020 -13.442 25.901  1.00 23.81  ? 317 GLN B NE2 1 
ATOM   5650  N  N   . GLY B 1 339 ? -39.725 -9.312  22.644  1.00 24.04  ? 318 GLY B N   1 
ATOM   5651  C  CA  . GLY B 1 339 ? -38.755 -8.333  22.236  1.00 25.53  ? 318 GLY B CA  1 
ATOM   5652  C  C   . GLY B 1 339 ? -39.285 -7.211  21.362  1.00 23.35  ? 318 GLY B C   1 
ATOM   5653  O  O   . GLY B 1 339 ? -38.622 -6.178  21.247  1.00 25.90  ? 318 GLY B O   1 
ATOM   5654  N  N   . GLN B 1 340 ? -40.443 -7.381  20.730  1.00 21.45  ? 319 GLN B N   1 
ATOM   5655  C  CA  . GLN B 1 340 ? -40.951 -6.314  19.885  1.00 19.57  ? 319 GLN B CA  1 
ATOM   5656  C  C   . GLN B 1 340 ? -41.446 -5.171  20.753  1.00 23.52  ? 319 GLN B C   1 
ATOM   5657  O  O   . GLN B 1 340 ? -41.693 -5.332  21.952  1.00 25.05  ? 319 GLN B O   1 
ATOM   5658  C  CB  . GLN B 1 340 ? -42.087 -6.818  19.010  1.00 21.77  ? 319 GLN B CB  1 
ATOM   5659  C  CG  . GLN B 1 340 ? -43.404 -6.880  19.689  1.00 27.22  ? 319 GLN B CG  1 
ATOM   5660  C  CD  . GLN B 1 340 ? -44.510 -6.905  18.674  1.00 32.72  ? 319 GLN B CD  1 
ATOM   5661  O  OE1 . GLN B 1 340 ? -44.755 -7.950  18.062  1.00 26.74  ? 319 GLN B OE1 1 
ATOM   5662  N  NE2 . GLN B 1 340 ? -45.159 -5.731  18.433  1.00 27.66  ? 319 GLN B NE2 1 
ATOM   5663  N  N   . ARG B 1 341 ? -41.617 -4.010  20.141  1.00 23.35  ? 320 ARG B N   1 
ATOM   5664  C  CA  . ARG B 1 341 ? -42.196 -2.906  20.891  1.00 21.70  ? 320 ARG B CA  1 
ATOM   5665  C  C   . ARG B 1 341 ? -43.721 -2.953  20.859  1.00 23.49  ? 320 ARG B C   1 
ATOM   5666  O  O   . ARG B 1 341 ? -44.326 -3.372  19.870  1.00 22.72  ? 320 ARG B O   1 
ATOM   5667  C  CB  . ARG B 1 341 ? -41.690 -1.594  20.340  1.00 19.42  ? 320 ARG B CB  1 
ATOM   5668  C  CG  . ARG B 1 341 ? -40.296 -1.279  20.891  1.00 21.76  ? 320 ARG B CG  1 
ATOM   5669  C  CD  . ARG B 1 341 ? -39.852 0.070   20.368  1.00 24.43  ? 320 ARG B CD  1 
ATOM   5670  N  NE  . ARG B 1 341 ? -38.539 0.376   20.911  1.00 27.47  ? 320 ARG B NE  1 
ATOM   5671  C  CZ  . ARG B 1 341 ? -37.401 -0.096  20.423  1.00 34.60  ? 320 ARG B CZ  1 
ATOM   5672  N  NH1 . ARG B 1 341 ? -37.371 -0.851  19.329  1.00 29.38  ? 320 ARG B NH1 1 
ATOM   5673  N  NH2 . ARG B 1 341 ? -36.265 0.198   21.046  1.00 34.77  ? 320 ARG B NH2 1 
ATOM   5674  N  N   . VAL B 1 342 ? -44.336 -2.541  21.958  1.00 23.26  ? 321 VAL B N   1 
ATOM   5675  C  CA  . VAL B 1 342 ? -45.738 -2.130  21.973  1.00 24.17  ? 321 VAL B CA  1 
ATOM   5676  C  C   . VAL B 1 342 ? -45.716 -0.651  22.307  1.00 26.32  ? 321 VAL B C   1 
ATOM   5677  O  O   . VAL B 1 342 ? -45.055 -0.241  23.269  1.00 23.56  ? 321 VAL B O   1 
ATOM   5678  C  CB  . VAL B 1 342 ? -46.578 -2.924  22.994  1.00 21.67  ? 321 VAL B CB  1 
ATOM   5679  C  CG1 . VAL B 1 342 ? -48.007 -2.334  23.082  1.00 24.52  ? 321 VAL B CG1 1 
ATOM   5680  C  CG2 . VAL B 1 342 ? -46.676 -4.414  22.590  1.00 21.96  ? 321 VAL B CG2 1 
ATOM   5681  N  N   . ILE B 1 343 ? -46.396 0.153   21.498  1.00 23.60  ? 322 ILE B N   1 
ATOM   5682  C  CA  . ILE B 1 343 ? -46.367 1.595   21.666  1.00 19.99  ? 322 ILE B CA  1 
ATOM   5683  C  C   . ILE B 1 343 ? -47.790 2.043   21.961  1.00 25.54  ? 322 ILE B C   1 
ATOM   5684  O  O   . ILE B 1 343 ? -48.688 1.791   21.153  1.00 22.03  ? 322 ILE B O   1 
ATOM   5685  C  CB  . ILE B 1 343 ? -45.812 2.276   20.419  1.00 24.05  ? 322 ILE B CB  1 
ATOM   5686  C  CG1 . ILE B 1 343 ? -44.321 1.914   20.249  1.00 24.74  ? 322 ILE B CG1 1 
ATOM   5687  C  CG2 . ILE B 1 343 ? -45.995 3.817   20.493  1.00 26.07  ? 322 ILE B CG2 1 
ATOM   5688  C  CD1 . ILE B 1 343 ? -43.829 2.307   18.864  1.00 31.70  ? 322 ILE B CD1 1 
ATOM   5689  N  N   . LEU B 1 344 ? -48.000 2.664   23.127  1.00 20.67  ? 323 LEU B N   1 
ATOM   5690  C  CA  . LEU B 1 344 ? -49.301 3.252   23.460  1.00 20.03  ? 323 LEU B CA  1 
ATOM   5691  C  C   . LEU B 1 344 ? -49.399 4.653   22.847  1.00 19.63  ? 323 LEU B C   1 
ATOM   5692  O  O   . LEU B 1 344 ? -48.548 5.515   23.096  1.00 21.30  ? 323 LEU B O   1 
ATOM   5693  C  CB  . LEU B 1 344 ? -49.487 3.317   24.976  1.00 18.78  ? 323 LEU B CB  1 
ATOM   5694  C  CG  . LEU B 1 344 ? -50.808 3.878   25.527  1.00 22.29  ? 323 LEU B CG  1 
ATOM   5695  C  CD1 . LEU B 1 344 ? -52.051 3.101   25.038  1.00 20.70  ? 323 LEU B CD1 1 
ATOM   5696  C  CD2 . LEU B 1 344 ? -50.697 3.858   27.054  1.00 24.05  ? 323 LEU B CD2 1 
ATOM   5697  N  N   . ASP B 1 345 ? -50.408 4.857   22.004  1.00 21.49  ? 324 ASP B N   1 
ATOM   5698  C  CA  . ASP B 1 345 ? -50.629 6.125   21.318  1.00 22.97  ? 324 ASP B CA  1 
ATOM   5699  C  C   . ASP B 1 345 ? -51.399 7.031   22.278  1.00 22.70  ? 324 ASP B C   1 
ATOM   5700  O  O   . ASP B 1 345 ? -52.565 6.765   22.582  1.00 23.60  ? 324 ASP B O   1 
ATOM   5701  C  CB  . ASP B 1 345 ? -51.396 5.842   20.026  1.00 21.16  ? 324 ASP B CB  1 
ATOM   5702  C  CG  . ASP B 1 345 ? -51.973 7.096   19.357  1.00 28.51  ? 324 ASP B CG  1 
ATOM   5703  O  OD1 . ASP B 1 345 ? -51.551 8.250   19.631  1.00 24.86  ? 324 ASP B OD1 1 
ATOM   5704  O  OD2 . ASP B 1 345 ? -52.889 6.893   18.546  1.00 27.79  ? 324 ASP B OD2 1 
ATOM   5705  N  N   . PHE B 1 346 ? -50.730 8.053   22.816  1.00 22.13  ? 325 PHE B N   1 
ATOM   5706  C  CA  . PHE B 1 346 ? -51.385 8.935   23.783  1.00 25.44  ? 325 PHE B CA  1 
ATOM   5707  C  C   . PHE B 1 346 ? -52.373 9.873   23.104  1.00 22.28  ? 325 PHE B C   1 
ATOM   5708  O  O   . PHE B 1 346 ? -53.511 10.033  23.567  1.00 21.06  ? 325 PHE B O   1 
ATOM   5709  C  CB  . PHE B 1 346 ? -50.333 9.739   24.556  1.00 20.60  ? 325 PHE B CB  1 
ATOM   5710  C  CG  . PHE B 1 346 ? -49.669 8.958   25.692  1.00 21.85  ? 325 PHE B CG  1 
ATOM   5711  C  CD1 . PHE B 1 346 ? -49.233 7.658   25.506  1.00 23.22  ? 325 PHE B CD1 1 
ATOM   5712  C  CD2 . PHE B 1 346 ? -49.418 9.574   26.911  1.00 23.42  ? 325 PHE B CD2 1 
ATOM   5713  C  CE1 . PHE B 1 346 ? -48.584 6.968   26.552  1.00 22.83  ? 325 PHE B CE1 1 
ATOM   5714  C  CE2 . PHE B 1 346 ? -48.787 8.896   27.960  1.00 20.89  ? 325 PHE B CE2 1 
ATOM   5715  C  CZ  . PHE B 1 346 ? -48.387 7.609   27.800  1.00 19.51  ? 325 PHE B CZ  1 
ATOM   5716  N  N   . VAL B 1 347 ? -51.949 10.528  22.024  1.00 21.37  ? 326 VAL B N   1 
ATOM   5717  C  CA  . VAL B 1 347 ? -52.847 11.461  21.333  1.00 27.97  ? 326 VAL B CA  1 
ATOM   5718  C  C   . VAL B 1 347 ? -54.125 10.764  20.885  1.00 27.61  ? 326 VAL B C   1 
ATOM   5719  O  O   . VAL B 1 347 ? -55.231 11.297  21.042  1.00 24.78  ? 326 VAL B O   1 
ATOM   5720  C  CB  . VAL B 1 347 ? -52.135 12.098  20.131  1.00 28.72  ? 326 VAL B CB  1 
ATOM   5721  C  CG1 . VAL B 1 347 ? -53.145 12.929  19.310  1.00 31.43  ? 326 VAL B CG1 1 
ATOM   5722  C  CG2 . VAL B 1 347 ? -50.979 12.993  20.605  1.00 25.68  ? 326 VAL B CG2 1 
ATOM   5723  N  N   . GLY B 1 348 ? -53.990 9.569   20.299  1.00 21.97  ? 327 GLY B N   1 
ATOM   5724  C  CA  . GLY B 1 348 ? -55.149 8.811   19.857  1.00 23.25  ? 327 GLY B CA  1 
ATOM   5725  C  C   . GLY B 1 348 ? -55.998 8.225   20.972  1.00 25.12  ? 327 GLY B C   1 
ATOM   5726  O  O   . GLY B 1 348 ? -57.134 7.816   20.715  1.00 25.91  ? 327 GLY B O   1 
ATOM   5727  N  N   . THR B 1 349 ? -55.485 8.161   22.197  1.00 19.65  ? 328 THR B N   1 
ATOM   5728  C  CA  . THR B 1 349 ? -56.348 7.791   23.314  1.00 18.89  ? 328 THR B CA  1 
ATOM   5729  C  C   . THR B 1 349 ? -57.067 9.005   23.902  1.00 21.99  ? 328 THR B C   1 
ATOM   5730  O  O   . THR B 1 349 ? -58.251 8.932   24.263  1.00 22.78  ? 328 THR B O   1 
ATOM   5731  C  CB  . THR B 1 349 ? -55.521 7.097   24.404  1.00 22.10  ? 328 THR B CB  1 
ATOM   5732  O  OG1 . THR B 1 349 ? -54.896 5.920   23.839  1.00 24.33  ? 328 THR B OG1 1 
ATOM   5733  C  CG2 . THR B 1 349 ? -56.394 6.732   25.608  1.00 20.27  ? 328 THR B CG2 1 
ATOM   5734  N  N   . LEU B 1 350 ? -56.350 10.114  24.014  1.00 17.86  ? 329 LEU B N   1 
ATOM   5735  C  CA  . LEU B 1 350 ? -56.928 11.372  24.477  1.00 20.71  ? 329 LEU B CA  1 
ATOM   5736  C  C   . LEU B 1 350 ? -57.925 11.956  23.481  1.00 24.33  ? 329 LEU B C   1 
ATOM   5737  O  O   . LEU B 1 350 ? -58.771 12.769  23.884  1.00 24.80  ? 329 LEU B O   1 
ATOM   5738  C  CB  . LEU B 1 350 ? -55.800 12.378  24.748  1.00 22.90  ? 329 LEU B CB  1 
ATOM   5739  C  CG  . LEU B 1 350 ? -54.831 11.996  25.874  1.00 22.65  ? 329 LEU B CG  1 
ATOM   5740  C  CD1 . LEU B 1 350 ? -53.570 12.889  25.736  1.00 23.36  ? 329 LEU B CD1 1 
ATOM   5741  C  CD2 . LEU B 1 350 ? -55.449 12.213  27.222  1.00 20.10  ? 329 LEU B CD2 1 
ATOM   5742  N  N   . HIS B 1 351 ? -57.859 11.558  22.203  1.00 19.37  ? 330 HIS B N   1 
ATOM   5743  C  CA  . HIS B 1 351 ? -58.763 12.100  21.187  1.00 23.03  ? 330 HIS B CA  1 
ATOM   5744  C  C   . HIS B 1 351 ? -59.653 11.046  20.546  1.00 21.47  ? 330 HIS B C   1 
ATOM   5745  O  O   . HIS B 1 351 ? -60.285 11.320  19.521  1.00 22.34  ? 330 HIS B O   1 
ATOM   5746  C  CB  . HIS B 1 351 ? -57.960 12.828  20.101  1.00 19.38  ? 330 HIS B CB  1 
ATOM   5747  C  CG  . HIS B 1 351 ? -57.419 14.155  20.547  1.00 26.90  ? 330 HIS B CG  1 
ATOM   5748  N  ND1 . HIS B 1 351 ? -58.083 15.341  20.308  1.00 30.19  ? 330 HIS B ND1 1 
ATOM   5749  C  CD2 . HIS B 1 351 ? -56.299 14.481  21.240  1.00 26.80  ? 330 HIS B CD2 1 
ATOM   5750  C  CE1 . HIS B 1 351 ? -57.377 16.347  20.804  1.00 27.39  ? 330 HIS B CE1 1 
ATOM   5751  N  NE2 . HIS B 1 351 ? -56.299 15.851  21.384  1.00 25.94  ? 330 HIS B NE2 1 
ATOM   5752  N  N   . SER B 1 352 ? -59.736 9.871   21.128  1.00 19.84  ? 331 SER B N   1 
ATOM   5753  C  CA  . SER B 1 352 ? -60.554 8.813   20.555  1.00 24.78  ? 331 SER B CA  1 
ATOM   5754  C  C   . SER B 1 352 ? -62.041 9.132   20.705  1.00 28.70  ? 331 SER B C   1 
ATOM   5755  O  O   . SER B 1 352 ? -62.518 9.434   21.811  1.00 23.85  ? 331 SER B O   1 
ATOM   5756  C  CB  . SER B 1 352 ? -60.231 7.500   21.254  1.00 26.78  ? 331 SER B CB  1 
ATOM   5757  O  OG  . SER B 1 352 ? -61.295 6.610   21.097  1.00 29.40  ? 331 SER B OG  1 
ATOM   5758  N  N   . ALA B 1 353 ? -62.781 9.039   19.594  1.00 23.56  ? 332 ALA B N   1 
ATOM   5759  C  CA  . ALA B 1 353 ? -64.225 9.244   19.659  1.00 26.56  ? 332 ALA B CA  1 
ATOM   5760  C  C   . ALA B 1 353 ? -64.940 8.095   20.359  1.00 26.34  ? 332 ALA B C   1 
ATOM   5761  O  O   . ALA B 1 353 ? -66.083 8.267   20.808  1.00 30.06  ? 332 ALA B O   1 
ATOM   5762  C  CB  . ALA B 1 353 ? -64.781 9.429   18.246  1.00 31.96  ? 332 ALA B CB  1 
ATOM   5763  N  N   . GLU B 1 354 ? -64.307 6.925   20.458  1.00 27.27  ? 333 GLU B N   1 
ATOM   5764  C  CA  . GLU B 1 354 ? -64.909 5.845   21.231  1.00 29.72  ? 333 GLU B CA  1 
ATOM   5765  C  C   . GLU B 1 354 ? -64.833 6.107   22.730  1.00 36.43  ? 333 GLU B C   1 
ATOM   5766  O  O   . GLU B 1 354 ? -65.674 5.608   23.475  1.00 35.60  ? 333 GLU B O   1 
ATOM   5767  C  CB  . GLU B 1 354 ? -64.238 4.519   20.897  1.00 32.93  ? 333 GLU B CB  1 
ATOM   5768  C  CG  . GLU B 1 354 ? -64.430 4.125   19.468  1.00 46.60  ? 333 GLU B CG  1 
ATOM   5769  C  CD  . GLU B 1 354 ? -64.934 2.711   19.325  1.00 74.07  ? 333 GLU B CD  1 
ATOM   5770  O  OE1 . GLU B 1 354 ? -64.591 1.865   20.184  1.00 72.62  ? 333 GLU B OE1 1 
ATOM   5771  O  OE2 . GLU B 1 354 ? -65.674 2.450   18.352  1.00 76.10  ? 333 GLU B OE2 1 
ATOM   5772  N  N   . GLU B 1 355 ? -63.837 6.873   23.193  1.00 28.12  ? 334 GLU B N   1 
ATOM   5773  C  CA  . GLU B 1 355 ? -63.596 7.054   24.620  1.00 25.77  ? 334 GLU B CA  1 
ATOM   5774  C  C   . GLU B 1 355 ? -64.128 8.375   25.159  1.00 26.29  ? 334 GLU B C   1 
ATOM   5775  O  O   . GLU B 1 355 ? -64.223 8.521   26.382  1.00 31.45  ? 334 GLU B O   1 
ATOM   5776  C  CB  . GLU B 1 355 ? -62.087 7.012   24.941  1.00 28.07  ? 334 GLU B CB  1 
ATOM   5777  C  CG  . GLU B 1 355 ? -61.283 5.763   24.416  1.00 34.54  ? 334 GLU B CG  1 
ATOM   5778  C  CD  . GLU B 1 355 ? -61.409 4.534   25.318  1.00 44.15  ? 334 GLU B CD  1 
ATOM   5779  O  OE1 . GLU B 1 355 ? -61.847 4.668   26.485  1.00 43.03  ? 334 GLU B OE1 1 
ATOM   5780  O  OE2 . GLU B 1 355 ? -61.106 3.418   24.840  1.00 36.34  ? 334 GLU B OE2 1 
ATOM   5781  N  N   . TRP B 1 356 ? -64.388 9.357   24.289  1.00 24.58  ? 335 TRP B N   1 
ATOM   5782  C  CA  . TRP B 1 356 ? -64.770 10.716  24.679  1.00 21.95  ? 335 TRP B CA  1 
ATOM   5783  C  C   . TRP B 1 356 ? -65.924 11.199  23.806  1.00 26.59  ? 335 TRP B C   1 
ATOM   5784  O  O   . TRP B 1 356 ? -65.964 10.921  22.605  1.00 29.24  ? 335 TRP B O   1 
ATOM   5785  C  CB  . TRP B 1 356 ? -63.616 11.723  24.475  1.00 23.21  ? 335 TRP B CB  1 
ATOM   5786  C  CG  . TRP B 1 356 ? -62.334 11.365  25.150  1.00 23.56  ? 335 TRP B CG  1 
ATOM   5787  C  CD1 . TRP B 1 356 ? -61.308 10.599  24.645  1.00 25.15  ? 335 TRP B CD1 1 
ATOM   5788  C  CD2 . TRP B 1 356 ? -61.926 11.772  26.449  1.00 21.84  ? 335 TRP B CD2 1 
ATOM   5789  N  NE1 . TRP B 1 356 ? -60.320 10.464  25.591  1.00 23.67  ? 335 TRP B NE1 1 
ATOM   5790  C  CE2 . TRP B 1 356 ? -60.666 11.182  26.702  1.00 21.01  ? 335 TRP B CE2 1 
ATOM   5791  C  CE3 . TRP B 1 356 ? -62.512 12.562  27.437  1.00 22.34  ? 335 TRP B CE3 1 
ATOM   5792  C  CZ2 . TRP B 1 356 ? -59.970 11.400  27.892  1.00 20.31  ? 335 TRP B CZ2 1 
ATOM   5793  C  CZ3 . TRP B 1 356 ? -61.833 12.754  28.616  1.00 24.67  ? 335 TRP B CZ3 1 
ATOM   5794  C  CH2 . TRP B 1 356 ? -60.577 12.175  28.833  1.00 22.00  ? 335 TRP B CH2 1 
ATOM   5795  N  N   . ASP B 1 357 ? -66.789 12.022  24.379  1.00 23.75  ? 336 ASP B N   1 
ATOM   5796  C  CA  . ASP B 1 357 ? -67.783 12.745  23.570  1.00 24.10  ? 336 ASP B CA  1 
ATOM   5797  C  C   . ASP B 1 357 ? -67.137 13.967  22.922  1.00 25.43  ? 336 ASP B C   1 
ATOM   5798  O  O   . ASP B 1 357 ? -66.501 14.769  23.616  1.00 30.02  ? 336 ASP B O   1 
ATOM   5799  C  CB  . ASP B 1 357 ? -68.949 13.187  24.453  1.00 30.87  ? 336 ASP B CB  1 
ATOM   5800  C  CG  . ASP B 1 357 ? -69.711 12.002  25.036  1.00 50.83  ? 336 ASP B CG  1 
ATOM   5801  O  OD1 . ASP B 1 357 ? -69.782 10.951  24.354  1.00 67.36  ? 336 ASP B OD1 1 
ATOM   5802  O  OD2 . ASP B 1 357 ? -70.230 12.113  26.169  1.00 64.49  ? 336 ASP B OD2 1 
ATOM   5803  N  N   . ASN B 1 358 ? -67.297 14.117  21.609  1.00 25.55  ? 337 ASN B N   1 
ATOM   5804  C  CA  . ASN B 1 358 ? -66.744 15.248  20.869  1.00 29.69  ? 337 ASN B CA  1 
ATOM   5805  C  C   . ASN B 1 358 ? -65.280 15.539  21.227  1.00 27.71  ? 337 ASN B C   1 
ATOM   5806  O  O   . ASN B 1 358 ? -64.956 16.622  21.710  1.00 26.07  ? 337 ASN B O   1 
ATOM   5807  C  CB  . ASN B 1 358 ? -67.588 16.499  21.085  1.00 28.67  ? 337 ASN B CB  1 
ATOM   5808  C  CG  . ASN B 1 358 ? -69.039 16.291  20.679  1.00 34.17  ? 337 ASN B CG  1 
ATOM   5809  O  OD1 . ASN B 1 358 ? -69.940 16.462  21.491  1.00 34.35  ? 337 ASN B OD1 1 
ATOM   5810  N  ND2 . ASN B 1 358 ? -69.257 15.904  19.434  1.00 34.16  ? 337 ASN B ND2 1 
ATOM   5811  N  N   . PRO B 1 359 ? -64.375 14.585  20.977  1.00 24.91  ? 338 PRO B N   1 
ATOM   5812  C  CA  . PRO B 1 359 ? -62.981 14.780  21.427  1.00 24.14  ? 338 PRO B CA  1 
ATOM   5813  C  C   . PRO B 1 359 ? -62.295 15.934  20.740  1.00 22.94  ? 338 PRO B C   1 
ATOM   5814  O  O   . PRO B 1 359 ? -61.321 16.459  21.288  1.00 22.55  ? 338 PRO B O   1 
ATOM   5815  C  CB  . PRO B 1 359 ? -62.297 13.439  21.094  1.00 25.31  ? 338 PRO B CB  1 
ATOM   5816  C  CG  . PRO B 1 359 ? -63.199 12.836  19.952  1.00 23.69  ? 338 PRO B CG  1 
ATOM   5817  C  CD  . PRO B 1 359 ? -64.594 13.322  20.249  1.00 29.17  ? 338 PRO B CD  1 
ATOM   5818  N  N   . ALA B 1 360 ? -62.745 16.342  19.546  1.00 23.66  ? 339 ALA B N   1 
ATOM   5819  C  CA  . ALA B 1 360 ? -62.099 17.476  18.893  1.00 26.44  ? 339 ALA B CA  1 
ATOM   5820  C  C   . ALA B 1 360 ? -62.454 18.812  19.534  1.00 26.85  ? 339 ALA B C   1 
ATOM   5821  O  O   . ALA B 1 360 ? -61.859 19.826  19.172  1.00 22.41  ? 339 ALA B O   1 
ATOM   5822  C  CB  . ALA B 1 360 ? -62.483 17.539  17.411  1.00 27.22  ? 339 ALA B CB  1 
ATOM   5823  N  N   . SER B 1 361 ? -63.411 18.846  20.454  1.00 23.47  ? 340 SER B N   1 
ATOM   5824  C  CA  . SER B 1 361 ? -63.851 20.106  21.048  1.00 25.33  ? 340 SER B CA  1 
ATOM   5825  C  C   . SER B 1 361 ? -63.078 20.357  22.347  1.00 22.07  ? 340 SER B C   1 
ATOM   5826  O  O   . SER B 1 361 ? -63.040 19.490  23.221  1.00 25.17  ? 340 SER B O   1 
ATOM   5827  C  CB  . SER B 1 361 ? -65.365 20.033  21.311  1.00 24.86  ? 340 SER B CB  1 
ATOM   5828  O  OG  . SER B 1 361 ? -65.797 21.122  22.092  1.00 28.62  ? 340 SER B OG  1 
ATOM   5829  N  N   . PHE B 1 362 ? -62.465 21.536  22.468  1.00 24.79  ? 341 PHE B N   1 
ATOM   5830  C  CA  . PHE B 1 362 ? -61.859 21.962  23.732  1.00 24.13  ? 341 PHE B CA  1 
ATOM   5831  C  C   . PHE B 1 362 ? -62.979 22.380  24.678  1.00 26.55  ? 341 PHE B C   1 
ATOM   5832  O  O   . PHE B 1 362 ? -63.636 23.400  24.458  1.00 22.39  ? 341 PHE B O   1 
ATOM   5833  C  CB  . PHE B 1 362 ? -60.889 23.132  23.528  1.00 22.24  ? 341 PHE B CB  1 
ATOM   5834  C  CG  . PHE B 1 362 ? -60.267 23.609  24.823  1.00 23.64  ? 341 PHE B CG  1 
ATOM   5835  C  CD1 . PHE B 1 362 ? -59.139 22.970  25.335  1.00 23.58  ? 341 PHE B CD1 1 
ATOM   5836  C  CD2 . PHE B 1 362 ? -60.815 24.673  25.550  1.00 22.03  ? 341 PHE B CD2 1 
ATOM   5837  C  CE1 . PHE B 1 362 ? -58.557 23.385  26.513  1.00 23.47  ? 341 PHE B CE1 1 
ATOM   5838  C  CE2 . PHE B 1 362 ? -60.220 25.073  26.757  1.00 20.18  ? 341 PHE B CE2 1 
ATOM   5839  C  CZ  . PHE B 1 362 ? -59.096 24.432  27.224  1.00 23.55  ? 341 PHE B CZ  1 
ATOM   5840  N  N   . ASP B 1 363 ? -63.235 21.592  25.716  1.00 23.37  ? 342 ASP B N   1 
ATOM   5841  C  CA  . ASP B 1 363 ? -64.420 21.828  26.538  1.00 24.91  ? 342 ASP B CA  1 
ATOM   5842  C  C   . ASP B 1 363 ? -64.146 21.474  27.983  1.00 21.77  ? 342 ASP B C   1 
ATOM   5843  O  O   . ASP B 1 363 ? -64.369 20.335  28.418  1.00 26.30  ? 342 ASP B O   1 
ATOM   5844  C  CB  . ASP B 1 363 ? -65.622 21.050  26.020  1.00 29.63  ? 342 ASP B CB  1 
ATOM   5845  C  CG  . ASP B 1 363 ? -66.894 21.446  26.743  1.00 35.32  ? 342 ASP B CG  1 
ATOM   5846  O  OD1 . ASP B 1 363 ? -66.838 22.367  27.616  1.00 30.91  ? 342 ASP B OD1 1 
ATOM   5847  O  OD2 . ASP B 1 363 ? -67.930 20.830  26.440  1.00 34.55  ? 342 ASP B OD2 1 
ATOM   5848  N  N   . PRO B 1 364 ? -63.739 22.456  28.786  1.00 23.67  ? 343 PRO B N   1 
ATOM   5849  C  CA  . PRO B 1 364 ? -63.474 22.186  30.205  1.00 21.86  ? 343 PRO B CA  1 
ATOM   5850  C  C   . PRO B 1 364 ? -64.681 21.675  30.989  1.00 26.78  ? 343 PRO B C   1 
ATOM   5851  O  O   . PRO B 1 364 ? -64.503 21.125  32.079  1.00 24.37  ? 343 PRO B O   1 
ATOM   5852  C  CB  . PRO B 1 364 ? -63.012 23.551  30.745  1.00 23.46  ? 343 PRO B CB  1 
ATOM   5853  C  CG  . PRO B 1 364 ? -62.429 24.250  29.544  1.00 24.09  ? 343 PRO B CG  1 
ATOM   5854  C  CD  . PRO B 1 364 ? -63.312 23.803  28.381  1.00 22.15  ? 343 PRO B CD  1 
ATOM   5855  N  N   . GLU B 1 365 ? -65.897 21.832  30.472  1.00 23.76  ? 344 GLU B N   1 
ATOM   5856  C  CA  . GLU B 1 365 ? -67.056 21.287  31.164  1.00 27.57  ? 344 GLU B CA  1 
ATOM   5857  C  C   . GLU B 1 365 ? -66.908 19.788  31.394  1.00 29.55  ? 344 GLU B C   1 
ATOM   5858  O  O   . GLU B 1 365 ? -67.443 19.255  32.373  1.00 30.60  ? 344 GLU B O   1 
ATOM   5859  C  CB  . GLU B 1 365 ? -68.315 21.615  30.340  1.00 33.70  ? 344 GLU B CB  1 
ATOM   5860  C  CG  . GLU B 1 365 ? -69.589 21.767  31.143  1.00 49.11  ? 344 GLU B CG  1 
ATOM   5861  C  CD  . GLU B 1 365 ? -69.558 22.980  32.036  1.00 33.82  ? 344 GLU B CD  1 
ATOM   5862  O  OE1 . GLU B 1 365 ? -69.587 24.145  31.538  1.00 45.96  ? 344 GLU B OE1 1 
ATOM   5863  O  OE2 . GLU B 1 365 ? -69.486 22.752  33.249  1.00 52.75  ? 344 GLU B OE2 1 
ATOM   5864  N  N   . ARG B 1 366 ? -66.154 19.077  30.533  1.00 24.67  ? 345 ARG B N   1 
ATOM   5865  C  CA  . ARG B 1 366 ? -66.038 17.648  30.773  1.00 31.33  ? 345 ARG B CA  1 
ATOM   5866  C  C   . ARG B 1 366 ? -65.299 17.325  32.076  1.00 27.38  ? 345 ARG B C   1 
ATOM   5867  O  O   . ARG B 1 366 ? -65.438 16.197  32.567  1.00 30.85  ? 345 ARG B O   1 
ATOM   5868  C  CB  . ARG B 1 366 ? -65.411 16.934  29.548  1.00 35.37  ? 345 ARG B CB  1 
ATOM   5869  C  CG  . ARG B 1 366 ? -63.987 17.243  29.257  1.00 30.36  ? 345 ARG B CG  1 
ATOM   5870  C  CD  . ARG B 1 366 ? -63.446 16.465  28.015  1.00 28.78  ? 345 ARG B CD  1 
ATOM   5871  N  NE  . ARG B 1 366 ? -63.653 17.130  26.730  1.00 22.52  ? 345 ARG B NE  1 
ATOM   5872  C  CZ  . ARG B 1 366 ? -64.375 16.621  25.737  1.00 27.09  ? 345 ARG B CZ  1 
ATOM   5873  N  NH1 . ARG B 1 366 ? -65.076 15.507  25.893  1.00 24.66  ? 345 ARG B NH1 1 
ATOM   5874  N  NH2 . ARG B 1 366 ? -64.366 17.224  24.549  1.00 24.30  ? 345 ARG B NH2 1 
ATOM   5875  N  N   . PHE B 1 367 ? -64.562 18.277  32.682  1.00 23.26  ? 346 PHE B N   1 
ATOM   5876  C  CA  . PHE B 1 367 ? -63.896 18.041  33.962  1.00 23.81  ? 346 PHE B CA  1 
ATOM   5877  C  C   . PHE B 1 367 ? -64.515 18.788  35.136  1.00 25.19  ? 346 PHE B C   1 
ATOM   5878  O  O   . PHE B 1 367 ? -64.026 18.635  36.268  1.00 27.48  ? 346 PHE B O   1 
ATOM   5879  C  CB  . PHE B 1 367 ? -62.388 18.378  33.891  1.00 24.29  ? 346 PHE B CB  1 
ATOM   5880  C  CG  . PHE B 1 367 ? -61.626 17.453  32.982  1.00 28.73  ? 346 PHE B CG  1 
ATOM   5881  C  CD1 . PHE B 1 367 ? -61.288 16.182  33.406  1.00 33.13  ? 346 PHE B CD1 1 
ATOM   5882  C  CD2 . PHE B 1 367 ? -61.295 17.840  31.694  1.00 23.12  ? 346 PHE B CD2 1 
ATOM   5883  C  CE1 . PHE B 1 367 ? -60.607 15.275  32.547  1.00 32.59  ? 346 PHE B CE1 1 
ATOM   5884  C  CE2 . PHE B 1 367 ? -60.603 16.953  30.832  1.00 29.59  ? 346 PHE B CE2 1 
ATOM   5885  C  CZ  . PHE B 1 367 ? -60.274 15.669  31.266  1.00 23.06  ? 346 PHE B CZ  1 
ATOM   5886  N  N   . MET B 1 368 ? -65.609 19.531  34.925  1.00 25.85  ? 347 MET B N   1 
ATOM   5887  C  CA  . MET B 1 368 ? -66.168 20.327  36.021  1.00 27.14  ? 347 MET B CA  1 
ATOM   5888  C  C   . MET B 1 368 ? -66.730 19.474  37.157  1.00 33.68  ? 347 MET B C   1 
ATOM   5889  O  O   . MET B 1 368 ? -66.792 19.957  38.292  1.00 34.20  ? 347 MET B O   1 
ATOM   5890  C  CB  . MET B 1 368 ? -67.240 21.280  35.477  1.00 25.04  ? 347 MET B CB  1 
ATOM   5891  C  CG  . MET B 1 368 ? -66.618 22.520  34.796  1.00 27.58  ? 347 MET B CG  1 
ATOM   5892  S  SD  . MET B 1 368 ? -65.730 23.580  35.957  1.00 30.59  ? 347 MET B SD  1 
ATOM   5893  C  CE  . MET B 1 368 ? -67.103 24.241  36.956  1.00 31.95  ? 347 MET B CE  1 
ATOM   5894  N  N   . ALA B 1 369 ? -67.102 18.217  36.903  1.00 29.21  ? 348 ALA B N   1 
ATOM   5895  C  CA  . ALA B 1 369 ? -67.554 17.366  38.001  1.00 33.99  ? 348 ALA B CA  1 
ATOM   5896  C  C   . ALA B 1 369 ? -66.411 16.815  38.842  1.00 42.24  ? 348 ALA B C   1 
ATOM   5897  O  O   . ALA B 1 369 ? -66.669 16.209  39.888  1.00 43.89  ? 348 ALA B O   1 
ATOM   5898  C  CB  . ALA B 1 369 ? -68.394 16.202  37.474  1.00 38.57  ? 348 ALA B CB  1 
ATOM   5899  N  N   . TYR B 1 370 ? -65.163 16.997  38.428  1.00 30.53  ? 349 TYR B N   1 
ATOM   5900  C  CA  . TYR B 1 370 ? -64.023 16.468  39.159  1.00 27.81  ? 349 TYR B CA  1 
ATOM   5901  C  C   . TYR B 1 370 ? -63.365 17.586  39.957  1.00 42.75  ? 349 TYR B C   1 
ATOM   5902  O  O   . TYR B 1 370 ? -63.186 18.705  39.463  1.00 43.98  ? 349 TYR B O   1 
ATOM   5903  C  CB  . TYR B 1 370 ? -63.016 15.813  38.193  1.00 27.25  ? 349 TYR B CB  1 
ATOM   5904  C  CG  . TYR B 1 370 ? -63.626 14.627  37.483  1.00 30.76  ? 349 TYR B CG  1 
ATOM   5905  C  CD1 . TYR B 1 370 ? -64.501 14.811  36.426  1.00 27.42  ? 349 TYR B CD1 1 
ATOM   5906  C  CD2 . TYR B 1 370 ? -63.379 13.319  37.917  1.00 33.18  ? 349 TYR B CD2 1 
ATOM   5907  C  CE1 . TYR B 1 370 ? -65.104 13.751  35.790  1.00 26.30  ? 349 TYR B CE1 1 
ATOM   5908  C  CE2 . TYR B 1 370 ? -63.972 12.240  37.281  1.00 27.60  ? 349 TYR B CE2 1 
ATOM   5909  C  CZ  . TYR B 1 370 ? -64.827 12.459  36.215  1.00 32.99  ? 349 TYR B CZ  1 
ATOM   5910  O  OH  . TYR B 1 370 ? -65.413 11.398  35.579  1.00 30.51  ? 349 TYR B OH  1 
ATOM   5911  N  N   . GLU B 1 371 ? -63.030 17.291  41.203  1.00 36.96  ? 350 GLU B N   1 
ATOM   5912  C  CA  . GLU B 1 371 ? -62.460 18.311  42.069  1.00 39.92  ? 350 GLU B CA  1 
ATOM   5913  C  C   . GLU B 1 371 ? -60.958 18.168  42.256  1.00 39.98  ? 350 GLU B C   1 
ATOM   5914  O  O   . GLU B 1 371 ? -60.281 19.172  42.481  1.00 33.03  ? 350 GLU B O   1 
ATOM   5915  C  CB  . GLU B 1 371 ? -63.150 18.270  43.437  1.00 46.57  ? 350 GLU B CB  1 
ATOM   5916  C  CG  . GLU B 1 371 ? -62.731 19.362  44.402  1.00 73.95  ? 350 GLU B CG  1 
ATOM   5917  C  CD  . GLU B 1 371 ? -63.388 19.215  45.766  1.00 88.31  ? 350 GLU B CD  1 
ATOM   5918  O  OE1 . GLU B 1 371 ? -64.318 18.382  45.898  1.00 80.78  ? 350 GLU B OE1 1 
ATOM   5919  O  OE2 . GLU B 1 371 ? -62.964 19.930  46.703  1.00 86.39  ? 350 GLU B OE2 1 
ATOM   5920  N  N   . THR B 1 372 ? -60.418 16.953  42.170  1.00 26.95  ? 351 THR B N   1 
ATOM   5921  C  CA  . THR B 1 372 ? -59.025 16.704  42.494  1.00 29.87  ? 351 THR B CA  1 
ATOM   5922  C  C   . THR B 1 372 ? -58.411 15.832  41.408  1.00 26.87  ? 351 THR B C   1 
ATOM   5923  O  O   . THR B 1 372 ? -59.125 15.169  40.649  1.00 29.85  ? 351 THR B O   1 
ATOM   5924  C  CB  . THR B 1 372 ? -58.882 15.978  43.844  1.00 40.22  ? 351 THR B CB  1 
ATOM   5925  O  OG1 . THR B 1 372 ? -59.466 14.674  43.719  1.00 34.75  ? 351 THR B OG1 1 
ATOM   5926  C  CG2 . THR B 1 372 ? -59.609 16.732  44.968  1.00 44.84  ? 351 THR B CG2 1 
ATOM   5927  N  N   . GLN B 1 373 ? -57.076 15.852  41.341  1.00 26.37  ? 352 GLN B N   1 
ATOM   5928  C  CA  . GLN B 1 373 ? -56.366 14.957  40.430  1.00 29.03  ? 352 GLN B CA  1 
ATOM   5929  C  C   . GLN B 1 373 ? -56.640 13.491  40.769  1.00 32.81  ? 352 GLN B C   1 
ATOM   5930  O  O   . GLN B 1 373 ? -56.787 12.650  39.867  1.00 28.37  ? 352 GLN B O   1 
ATOM   5931  C  CB  . GLN B 1 373 ? -54.862 15.276  40.457  1.00 29.63  ? 352 GLN B CB  1 
ATOM   5932  C  CG  . GLN B 1 373 ? -53.972 14.346  39.614  1.00 28.80  ? 352 GLN B CG  1 
ATOM   5933  C  CD  . GLN B 1 373 ? -54.500 14.065  38.206  1.00 30.68  ? 352 GLN B CD  1 
ATOM   5934  O  OE1 . GLN B 1 373 ? -55.176 14.898  37.596  1.00 28.60  ? 352 GLN B OE1 1 
ATOM   5935  N  NE2 . GLN B 1 373 ? -54.161 12.889  37.672  1.00 26.83  ? 352 GLN B NE2 1 
ATOM   5936  N  N   . SER B 1 374 ? -56.744 13.169  42.062  1.00 30.31  ? 353 SER B N   1 
ATOM   5937  C  CA  . SER B 1 374 ? -57.091 11.801  42.440  1.00 29.61  ? 353 SER B CA  1 
ATOM   5938  C  C   . SER B 1 374 ? -58.411 11.364  41.813  1.00 33.49  ? 353 SER B C   1 
ATOM   5939  O  O   . SER B 1 374 ? -58.515 10.245  41.297  1.00 33.04  ? 353 SER B O   1 
ATOM   5940  C  CB  . SER B 1 374 ? -57.119 11.675  43.970  1.00 35.33  ? 353 SER B CB  1 
ATOM   5941  O  OG  . SER B 1 374 ? -57.309 10.326  44.346  1.00 49.74  ? 353 SER B OG  1 
ATOM   5942  N  N   . GLU B 1 375 ? -59.435 12.236  41.809  1.00 30.76  ? 354 GLU B N   1 
ATOM   5943  C  CA  . GLU B 1 375 ? -60.684 11.866  41.143  1.00 29.39  ? 354 GLU B CA  1 
ATOM   5944  C  C   . GLU B 1 375 ? -60.499 11.706  39.631  1.00 26.76  ? 354 GLU B C   1 
ATOM   5945  O  O   . GLU B 1 375 ? -61.125 10.835  39.008  1.00 27.55  ? 354 GLU B O   1 
ATOM   5946  C  CB  . GLU B 1 375 ? -61.786 12.900  41.438  1.00 29.18  ? 354 GLU B CB  1 
ATOM   5947  C  CG  . GLU B 1 375 ? -62.150 12.925  42.918  1.00 37.94  ? 354 GLU B CG  1 
ATOM   5948  C  CD  . GLU B 1 375 ? -63.143 14.017  43.299  1.00 50.61  ? 354 GLU B CD  1 
ATOM   5949  O  OE1 . GLU B 1 375 ? -63.645 14.754  42.413  1.00 41.47  ? 354 GLU B OE1 1 
ATOM   5950  O  OE2 . GLU B 1 375 ? -63.425 14.124  44.506  1.00 53.18  ? 354 GLU B OE2 1 
ATOM   5951  N  N   . ALA B 1 376 ? -59.670 12.549  39.022  1.00 28.69  ? 355 ALA B N   1 
ATOM   5952  C  CA  . ALA B 1 376 ? -59.432 12.445  37.583  1.00 25.86  ? 355 ALA B CA  1 
ATOM   5953  C  C   . ALA B 1 376 ? -58.724 11.148  37.209  1.00 25.45  ? 355 ALA B C   1 
ATOM   5954  O  O   . ALA B 1 376 ? -58.889 10.681  36.077  1.00 26.82  ? 355 ALA B O   1 
ATOM   5955  C  CB  . ALA B 1 376 ? -58.634 13.665  37.089  1.00 23.67  ? 355 ALA B CB  1 
ATOM   5956  N  N   . GLU B 1 377 ? -57.997 10.519  38.139  1.00 28.82  ? 356 GLU B N   1 
ATOM   5957  C  CA  . GLU B 1 377 ? -57.395 9.210   37.858  1.00 27.98  ? 356 GLU B CA  1 
ATOM   5958  C  C   . GLU B 1 377 ? -58.411 8.128   37.559  1.00 33.29  ? 356 GLU B C   1 
ATOM   5959  O  O   . GLU B 1 377 ? -58.039 7.109   36.976  1.00 35.26  ? 356 GLU B O   1 
ATOM   5960  C  CB  . GLU B 1 377 ? -56.547 8.729   39.021  1.00 34.72  ? 356 GLU B CB  1 
ATOM   5961  C  CG  . GLU B 1 377 ? -55.283 9.510   39.226  1.00 31.22  ? 356 GLU B CG  1 
ATOM   5962  C  CD  . GLU B 1 377 ? -54.532 9.067   40.478  1.00 37.18  ? 356 GLU B CD  1 
ATOM   5963  O  OE1 . GLU B 1 377 ? -55.106 8.308   41.293  1.00 50.60  ? 356 GLU B OE1 1 
ATOM   5964  O  OE2 . GLU B 1 377 ? -53.371 9.482   40.655  1.00 36.65  ? 356 GLU B OE2 1 
ATOM   5965  N  N   . THR B 1 378 ? -59.675 8.298   37.962  1.00 30.48  ? 357 THR B N   1 
ATOM   5966  C  CA  . THR B 1 378 ? -60.676 7.288   37.650  1.00 23.13  ? 357 THR B CA  1 
ATOM   5967  C  C   . THR B 1 378 ? -61.107 7.341   36.196  1.00 30.63  ? 357 THR B C   1 
ATOM   5968  O  O   . THR B 1 378 ? -61.882 6.489   35.750  1.00 31.76  ? 357 THR B O   1 
ATOM   5969  C  CB  . THR B 1 378 ? -61.907 7.460   38.546  1.00 31.15  ? 357 THR B CB  1 
ATOM   5970  O  OG1 . THR B 1 378 ? -62.590 8.665   38.188  1.00 30.66  ? 357 THR B OG1 1 
ATOM   5971  C  CG2 . THR B 1 378 ? -61.499 7.561   39.998  1.00 32.56  ? 357 THR B CG2 1 
ATOM   5972  N  N   . ILE B 1 379 ? -60.668 8.344   35.447  1.00 25.26  ? 358 ILE B N   1 
ATOM   5973  C  CA  . ILE B 1 379 ? -61.033 8.447   34.043  1.00 24.18  ? 358 ILE B CA  1 
ATOM   5974  C  C   . ILE B 1 379 ? -60.021 7.631   33.247  1.00 27.62  ? 358 ILE B C   1 
ATOM   5975  O  O   . ILE B 1 379 ? -58.877 8.054   33.037  1.00 23.16  ? 358 ILE B O   1 
ATOM   5976  C  CB  . ILE B 1 379 ? -61.080 9.898   33.581  1.00 21.97  ? 358 ILE B CB  1 
ATOM   5977  C  CG1 . ILE B 1 379 ? -62.025 10.730  34.474  1.00 22.80  ? 358 ILE B CG1 1 
ATOM   5978  C  CG2 . ILE B 1 379 ? -61.527 9.960   32.098  1.00 23.81  ? 358 ILE B CG2 1 
ATOM   5979  C  CD1 . ILE B 1 379 ? -61.926 12.294  34.128  1.00 23.86  ? 358 ILE B CD1 1 
ATOM   5980  N  N   . LYS B 1 380 ? -60.436 6.455   32.788  1.00 26.71  ? 359 LYS B N   1 
ATOM   5981  C  CA  . LYS B 1 380 ? -59.448 5.524   32.249  1.00 25.19  ? 359 LYS B CA  1 
ATOM   5982  C  C   . LYS B 1 380 ? -58.710 6.038   31.015  1.00 22.41  ? 359 LYS B C   1 
ATOM   5983  O  O   . LYS B 1 380 ? -57.485 5.854   30.947  1.00 25.18  ? 359 LYS B O   1 
ATOM   5984  C  CB  . LYS B 1 380 ? -60.112 4.170   31.981  1.00 26.99  ? 359 LYS B CB  1 
ATOM   5985  C  CG  . LYS B 1 380 ? -59.139 3.132   31.473  1.00 31.32  ? 359 LYS B CG  1 
ATOM   5986  C  CD  . LYS B 1 380 ? -59.689 1.734   31.731  1.00 35.92  ? 359 LYS B CD  1 
ATOM   5987  C  CE  . LYS B 1 380 ? -58.602 0.715   31.476  1.00 38.34  ? 359 LYS B CE  1 
ATOM   5988  N  NZ  . LYS B 1 380 ? -59.213 -0.578  31.108  1.00 44.66  ? 359 LYS B NZ  1 
ATOM   5989  N  N   . PRO B 1 381 ? -59.351 6.630   30.005  1.00 22.56  ? 360 PRO B N   1 
ATOM   5990  C  CA  . PRO B 1 381 ? -58.578 7.132   28.859  1.00 22.57  ? 360 PRO B CA  1 
ATOM   5991  C  C   . PRO B 1 381 ? -57.904 8.480   29.084  1.00 23.75  ? 360 PRO B C   1 
ATOM   5992  O  O   . PRO B 1 381 ? -57.292 9.003   28.154  1.00 19.46  ? 360 PRO B O   1 
ATOM   5993  C  CB  . PRO B 1 381 ? -59.637 7.243   27.754  1.00 29.80  ? 360 PRO B CB  1 
ATOM   5994  C  CG  . PRO B 1 381 ? -60.876 7.577   28.484  1.00 26.71  ? 360 PRO B CG  1 
ATOM   5995  C  CD  . PRO B 1 381 ? -60.808 6.780   29.779  1.00 25.87  ? 360 PRO B CD  1 
ATOM   5996  N  N   . PHE B 1 382 ? -57.979 9.065   30.274  1.00 20.05  ? 361 PHE B N   1 
ATOM   5997  C  CA  . PHE B 1 382 ? -57.337 10.356  30.510  1.00 20.71  ? 361 PHE B CA  1 
ATOM   5998  C  C   . PHE B 1 382 ? -55.902 10.053  30.945  1.00 21.87  ? 361 PHE B C   1 
ATOM   5999  O  O   . PHE B 1 382 ? -55.600 9.965   32.132  1.00 21.08  ? 361 PHE B O   1 
ATOM   6000  C  CB  . PHE B 1 382 ? -58.115 11.137  31.563  1.00 19.22  ? 361 PHE B CB  1 
ATOM   6001  C  CG  . PHE B 1 382 ? -57.607 12.542  31.797  1.00 23.31  ? 361 PHE B CG  1 
ATOM   6002  C  CD1 . PHE B 1 382 ? -57.209 13.342  30.734  1.00 19.50  ? 361 PHE B CD1 1 
ATOM   6003  C  CD2 . PHE B 1 382 ? -57.521 13.046  33.103  1.00 20.75  ? 361 PHE B CD2 1 
ATOM   6004  C  CE1 . PHE B 1 382 ? -56.754 14.647  30.951  1.00 18.40  ? 361 PHE B CE1 1 
ATOM   6005  C  CE2 . PHE B 1 382 ? -57.039 14.321  33.352  1.00 19.71  ? 361 PHE B CE2 1 
ATOM   6006  C  CZ  . PHE B 1 382 ? -56.647 15.125  32.295  1.00 19.52  ? 361 PHE B CZ  1 
ATOM   6007  N  N   . ILE B 1 383 ? -55.015 9.897   29.964  1.00 21.97  ? 362 ILE B N   1 
ATOM   6008  C  CA  . ILE B 1 383 ? -53.645 9.447   30.225  1.00 19.96  ? 362 ILE B CA  1 
ATOM   6009  C  C   . ILE B 1 383 ? -52.583 10.408  29.700  1.00 19.79  ? 362 ILE B C   1 
ATOM   6010  O  O   . ILE B 1 383 ? -51.571 9.944   29.152  1.00 20.93  ? 362 ILE B O   1 
ATOM   6011  C  CB  . ILE B 1 383 ? -53.413 8.067   29.592  1.00 20.33  ? 362 ILE B CB  1 
ATOM   6012  C  CG1 . ILE B 1 383 ? -53.680 8.149   28.085  1.00 19.98  ? 362 ILE B CG1 1 
ATOM   6013  C  CG2 . ILE B 1 383 ? -54.313 7.041   30.260  1.00 19.04  ? 362 ILE B CG2 1 
ATOM   6014  C  CD1 . ILE B 1 383 ? -53.029 6.916   27.279  1.00 22.88  ? 362 ILE B CD1 1 
ATOM   6015  N  N   . PRO B 1 384 ? -52.724 11.733  29.862  1.00 19.04  ? 363 PRO B N   1 
ATOM   6016  C  CA  . PRO B 1 384 ? -51.680 12.635  29.361  1.00 18.14  ? 363 PRO B CA  1 
ATOM   6017  C  C   . PRO B 1 384 ? -50.303 12.362  29.969  1.00 21.05  ? 363 PRO B C   1 
ATOM   6018  O  O   . PRO B 1 384 ? -49.279 12.751  29.381  1.00 21.25  ? 363 PRO B O   1 
ATOM   6019  C  CB  . PRO B 1 384 ? -52.209 14.028  29.759  1.00 22.01  ? 363 PRO B CB  1 
ATOM   6020  C  CG  . PRO B 1 384 ? -53.016 13.746  31.045  1.00 21.35  ? 363 PRO B CG  1 
ATOM   6021  C  CD  . PRO B 1 384 ? -53.716 12.446  30.702  1.00 19.69  ? 363 PRO B CD  1 
ATOM   6022  N  N   . GLN B 1 385 ? -50.247 11.718  31.129  1.00 20.76  ? 364 GLN B N   1 
ATOM   6023  C  CA  . GLN B 1 385 ? -48.977 11.377  31.758  1.00 20.92  ? 364 GLN B CA  1 
ATOM   6024  C  C   . GLN B 1 385 ? -48.986 9.910   32.158  1.00 21.41  ? 364 GLN B C   1 
ATOM   6025  O  O   . GLN B 1 385 ? -48.403 9.547   33.170  1.00 21.39  ? 364 GLN B O   1 
ATOM   6026  C  CB  . GLN B 1 385 ? -48.679 12.297  32.962  1.00 20.22  ? 364 GLN B CB  1 
ATOM   6027  C  CG  . GLN B 1 385 ? -48.735 13.777  32.506  1.00 23.63  ? 364 GLN B CG  1 
ATOM   6028  C  CD  . GLN B 1 385 ? -48.511 14.898  33.572  1.00 24.95  ? 364 GLN B CD  1 
ATOM   6029  O  OE1 . GLN B 1 385 ? -49.021 16.013  33.384  1.00 26.51  ? 364 GLN B OE1 1 
ATOM   6030  N  NE2 . GLN B 1 385 ? -47.699 14.644  34.609  1.00 19.59  ? 364 GLN B NE2 1 
ATOM   6031  N  N   . GLY B 1 386 ? -49.667 9.058   31.380  1.00 17.94  ? 365 GLY B N   1 
ATOM   6032  C  CA  . GLY B 1 386 ? -49.678 7.625   31.615  1.00 18.28  ? 365 GLY B CA  1 
ATOM   6033  C  C   . GLY B 1 386 ? -50.981 7.159   32.253  1.00 25.44  ? 365 GLY B C   1 
ATOM   6034  O  O   . GLY B 1 386 ? -51.787 7.948   32.778  1.00 20.06  ? 365 GLY B O   1 
ATOM   6035  N  N   . GLY B 1 387 ? -51.170 5.826   32.221  1.00 22.64  ? 366 GLY B N   1 
ATOM   6036  C  CA  . GLY B 1 387 ? -52.360 5.205   32.797  1.00 21.66  ? 366 GLY B CA  1 
ATOM   6037  C  C   . GLY B 1 387 ? -52.083 4.124   33.831  1.00 22.87  ? 366 GLY B C   1 
ATOM   6038  O  O   . GLY B 1 387 ? -50.938 3.947   34.275  1.00 22.04  ? 366 GLY B O   1 
ATOM   6039  N  N   . ALA B 1 388 ? -53.129 3.399   34.217  1.00 26.66  ? 367 ALA B N   1 
ATOM   6040  C  CA  . ALA B 1 388 ? -53.100 2.411   35.325  1.00 24.69  ? 367 ALA B CA  1 
ATOM   6041  C  C   . ALA B 1 388 ? -52.620 3.126   36.596  1.00 29.21  ? 367 ALA B C   1 
ATOM   6042  O  O   . ALA B 1 388 ? -52.968 4.294   36.820  1.00 26.91  ? 367 ALA B O   1 
ATOM   6043  C  CB  . ALA B 1 388 ? -52.274 1.204   34.904  1.00 27.27  ? 367 ALA B CB  1 
ATOM   6044  N  N   . ASP B 1 389 ? -51.805 2.487   37.426  1.00 27.98  ? 368 ASP B N   1 
ATOM   6045  C  CA  . ASP B 1 389 ? -51.598 2.897   38.808  1.00 29.96  ? 368 ASP B CA  1 
ATOM   6046  C  C   . ASP B 1 389 ? -50.211 3.496   39.025  1.00 31.03  ? 368 ASP B C   1 
ATOM   6047  O  O   . ASP B 1 389 ? -49.214 3.002   38.489  1.00 26.67  ? 368 ASP B O   1 
ATOM   6048  C  CB  . ASP B 1 389 ? -51.783 1.695   39.739  1.00 35.01  ? 368 ASP B CB  1 
ATOM   6049  C  CG  . ASP B 1 389 ? -51.672 2.081   41.201  1.00 52.80  ? 368 ASP B CG  1 
ATOM   6050  O  OD1 . ASP B 1 389 ? -52.614 2.728   41.711  1.00 56.05  ? 368 ASP B OD1 1 
ATOM   6051  O  OD2 . ASP B 1 389 ? -50.631 1.766   41.828  1.00 50.55  ? 368 ASP B OD2 1 
ATOM   6052  N  N   . VAL B 1 390 ? -50.146 4.548   39.844  1.00 25.79  ? 369 VAL B N   1 
ATOM   6053  C  CA  . VAL B 1 390 ? -48.883 5.262   40.034  1.00 26.34  ? 369 VAL B CA  1 
ATOM   6054  C  C   . VAL B 1 390 ? -47.864 4.401   40.781  1.00 29.22  ? 369 VAL B C   1 
ATOM   6055  O  O   . VAL B 1 390 ? -46.700 4.290   40.374  1.00 28.71  ? 369 VAL B O   1 
ATOM   6056  C  CB  . VAL B 1 390 ? -49.137 6.591   40.777  1.00 29.63  ? 369 VAL B CB  1 
ATOM   6057  C  CG1 . VAL B 1 390 ? -47.823 7.198   41.229  1.00 30.60  ? 369 VAL B CG1 1 
ATOM   6058  C  CG2 . VAL B 1 390 ? -49.882 7.544   39.882  1.00 29.78  ? 369 VAL B CG2 1 
ATOM   6059  N  N   . ARG B 1 391 ? -48.269 3.801   41.898  1.00 29.43  ? 370 ARG B N   1 
ATOM   6060  C  CA  . ARG B 1 391 ? -47.283 3.123   42.740  1.00 35.74  ? 370 ARG B CA  1 
ATOM   6061  C  C   . ARG B 1 391 ? -46.917 1.740   42.219  1.00 37.03  ? 370 ARG B C   1 
ATOM   6062  O  O   . ARG B 1 391 ? -45.774 1.304   42.391  1.00 41.90  ? 370 ARG B O   1 
ATOM   6063  C  CB  . ARG B 1 391 ? -47.795 3.021   44.182  1.00 41.58  ? 370 ARG B CB  1 
ATOM   6064  C  CG  . ARG B 1 391 ? -47.969 4.394   44.854  1.00 40.23  ? 370 ARG B CG  1 
ATOM   6065  C  CD  . ARG B 1 391 ? -48.286 4.298   46.362  1.00 56.78  ? 370 ARG B CD  1 
ATOM   6066  N  NE  . ARG B 1 391 ? -48.995 5.482   46.860  1.00 47.47  ? 370 ARG B NE  1 
ATOM   6067  C  CZ  . ARG B 1 391 ? -48.407 6.562   47.364  1.00 62.84  ? 370 ARG B CZ  1 
ATOM   6068  N  NH1 . ARG B 1 391 ? -47.086 6.666   47.441  1.00 51.99  ? 370 ARG B NH1 1 
ATOM   6069  N  NH2 . ARG B 1 391 ? -49.163 7.566   47.805  1.00 62.13  ? 370 ARG B NH2 1 
ATOM   6070  N  N   . THR B 1 392 ? -47.854 1.032   41.584  1.00 32.13  ? 371 THR B N   1 
ATOM   6071  C  CA  . THR B 1 392 ? -47.543 -0.318  41.139  1.00 38.42  ? 371 THR B CA  1 
ATOM   6072  C  C   . THR B 1 392 ? -47.064 -0.367  39.701  1.00 35.31  ? 371 THR B C   1 
ATOM   6073  O  O   . THR B 1 392 ? -46.641 -1.434  39.255  1.00 40.12  ? 371 THR B O   1 
ATOM   6074  C  CB  . THR B 1 392 ? -48.755 -1.256  41.281  1.00 36.96  ? 371 THR B CB  1 
ATOM   6075  O  OG1 . THR B 1 392 ? -49.805 -0.835  40.407  1.00 34.62  ? 371 THR B OG1 1 
ATOM   6076  C  CG2 . THR B 1 392 ? -49.279 -1.271  42.694  1.00 34.73  ? 371 THR B CG2 1 
ATOM   6077  N  N   . GLY B 1 393 ? -47.155 0.733   38.950  1.00 26.31  ? 372 GLY B N   1 
ATOM   6078  C  CA  . GLY B 1 393 ? -46.717 0.698   37.565  1.00 23.93  ? 372 GLY B CA  1 
ATOM   6079  C  C   . GLY B 1 393 ? -45.827 1.879   37.226  1.00 22.16  ? 372 GLY B C   1 
ATOM   6080  O  O   . GLY B 1 393 ? -45.267 2.515   38.126  1.00 26.26  ? 372 GLY B O   1 
ATOM   6081  N  N   . HIS B 1 394 ? -45.664 2.181   35.943  1.00 21.50  ? 373 HIS B N   1 
ATOM   6082  C  CA  . HIS B 1 394 ? -44.762 3.239   35.520  1.00 22.41  ? 373 HIS B CA  1 
ATOM   6083  C  C   . HIS B 1 394 ? -45.450 4.598   35.353  1.00 20.88  ? 373 HIS B C   1 
ATOM   6084  O  O   . HIS B 1 394 ? -44.794 5.563   34.952  1.00 19.64  ? 373 HIS B O   1 
ATOM   6085  C  CB  . HIS B 1 394 ? -44.067 2.833   34.221  1.00 22.37  ? 373 HIS B CB  1 
ATOM   6086  C  CG  . HIS B 1 394 ? -42.894 1.923   34.432  1.00 22.22  ? 373 HIS B CG  1 
ATOM   6087  N  ND1 . HIS B 1 394 ? -41.604 2.396   34.519  1.00 25.04  ? 373 HIS B ND1 1 
ATOM   6088  C  CD2 . HIS B 1 394 ? -42.816 0.579   34.575  1.00 22.77  ? 373 HIS B CD2 1 
ATOM   6089  C  CE1 . HIS B 1 394 ? -40.774 1.374   34.695  1.00 23.81  ? 373 HIS B CE1 1 
ATOM   6090  N  NE2 . HIS B 1 394 ? -41.484 0.261   34.736  1.00 21.76  ? 373 HIS B NE2 1 
ATOM   6091  N  N   . ARG B 1 395 ? -46.744 4.696   35.642  1.00 19.56  ? 374 ARG B N   1 
ATOM   6092  C  CA  . ARG B 1 395 ? -47.435 5.978   35.492  1.00 20.18  ? 374 ARG B CA  1 
ATOM   6093  C  C   . ARG B 1 395 ? -46.722 7.109   36.235  1.00 21.29  ? 374 ARG B C   1 
ATOM   6094  O  O   . ARG B 1 395 ? -46.108 6.917   37.293  1.00 20.22  ? 374 ARG B O   1 
ATOM   6095  C  CB  . ARG B 1 395 ? -48.864 5.844   36.002  1.00 20.68  ? 374 ARG B CB  1 
ATOM   6096  C  CG  . ARG B 1 395 ? -49.671 7.176   35.923  1.00 18.32  ? 374 ARG B CG  1 
ATOM   6097  C  CD  . ARG B 1 395 ? -51.130 6.887   36.335  1.00 24.47  ? 374 ARG B CD  1 
ATOM   6098  N  NE  . ARG B 1 395 ? -51.971 8.068   36.177  1.00 23.55  ? 374 ARG B NE  1 
ATOM   6099  C  CZ  . ARG B 1 395 ? -53.256 8.027   35.878  1.00 24.42  ? 374 ARG B CZ  1 
ATOM   6100  N  NH1 . ARG B 1 395 ? -53.897 6.872   35.780  1.00 21.72  ? 374 ARG B NH1 1 
ATOM   6101  N  NH2 . ARG B 1 395 ? -53.918 9.176   35.688  1.00 19.97  ? 374 ARG B NH2 1 
ATOM   6102  N  N   . CYS B 1 396 ? -46.781 8.292   35.635  1.00 23.20  ? 375 CYS B N   1 
ATOM   6103  C  CA  . CYS B 1 396 ? -46.205 9.501   36.216  1.00 22.84  ? 375 CYS B CA  1 
ATOM   6104  C  C   . CYS B 1 396 ? -46.654 9.722   37.665  1.00 18.20  ? 375 CYS B C   1 
ATOM   6105  O  O   . CYS B 1 396 ? -47.862 9.802   37.935  1.00 20.09  ? 375 CYS B O   1 
ATOM   6106  C  CB  . CYS B 1 396 ? -46.627 10.700  35.360  1.00 20.28  ? 375 CYS B CB  1 
ATOM   6107  S  SG  . CYS B 1 396 ? -45.904 12.293  35.911  1.00 22.60  ? 375 CYS B SG  1 
ATOM   6108  N  N   . PRO B 1 397 ? -45.725 9.891   38.602  1.00 22.47  ? 376 PRO B N   1 
ATOM   6109  C  CA  . PRO B 1 397 ? -46.082 10.249  39.984  1.00 25.46  ? 376 PRO B CA  1 
ATOM   6110  C  C   . PRO B 1 397 ? -46.235 11.752  40.199  1.00 27.45  ? 376 PRO B C   1 
ATOM   6111  O  O   . PRO B 1 397 ? -46.512 12.189  41.320  1.00 23.84  ? 376 PRO B O   1 
ATOM   6112  C  CB  . PRO B 1 397 ? -44.873 9.712   40.766  1.00 22.09  ? 376 PRO B CB  1 
ATOM   6113  C  CG  . PRO B 1 397 ? -43.723 9.963   39.830  1.00 20.95  ? 376 PRO B CG  1 
ATOM   6114  C  CD  . PRO B 1 397 ? -44.272 9.698   38.427  1.00 19.09  ? 376 PRO B CD  1 
ATOM   6115  N  N   . GLY B 1 398 ? -46.075 12.550  39.158  1.00 20.45  ? 377 GLY B N   1 
ATOM   6116  C  CA  . GLY B 1 398 ? -46.037 13.995  39.286  1.00 21.31  ? 377 GLY B CA  1 
ATOM   6117  C  C   . GLY B 1 398 ? -47.263 14.730  38.766  1.00 20.52  ? 377 GLY B C   1 
ATOM   6118  O  O   . GLY B 1 398 ? -47.200 15.949  38.607  1.00 23.09  ? 377 GLY B O   1 
ATOM   6119  N  N   . GLU B 1 399 ? -48.372 14.036  38.516  1.00 21.12  ? 378 GLU B N   1 
ATOM   6120  C  CA  . GLU B 1 399 ? -49.542 14.715  37.962  1.00 23.49  ? 378 GLU B CA  1 
ATOM   6121  C  C   . GLU B 1 399 ? -50.147 15.704  38.958  1.00 21.50  ? 378 GLU B C   1 
ATOM   6122  O  O   . GLU B 1 399 ? -50.744 16.707  38.547  1.00 24.68  ? 378 GLU B O   1 
ATOM   6123  C  CB  . GLU B 1 399 ? -50.624 13.717  37.557  1.00 23.17  ? 378 GLU B CB  1 
ATOM   6124  C  CG  . GLU B 1 399 ? -50.156 12.658  36.564  1.00 22.46  ? 378 GLU B CG  1 
ATOM   6125  C  CD  . GLU B 1 399 ? -51.345 11.975  35.915  1.00 22.71  ? 378 GLU B CD  1 
ATOM   6126  O  OE1 . GLU B 1 399 ? -51.890 12.536  34.955  1.00 26.77  ? 378 GLU B OE1 1 
ATOM   6127  O  OE2 . GLU B 1 399 ? -51.759 10.910  36.389  1.00 26.07  ? 378 GLU B OE2 1 
ATOM   6128  N  N   . LYS B 1 400 ? -50.039 15.435  40.261  1.00 22.04  ? 379 LYS B N   1 
ATOM   6129  C  CA  . LYS B 1 400 ? -50.592 16.416  41.198  1.00 24.06  ? 379 LYS B CA  1 
ATOM   6130  C  C   . LYS B 1 400 ? -49.747 17.684  41.198  1.00 25.35  ? 379 LYS B C   1 
ATOM   6131  O  O   . LYS B 1 400 ? -50.290 18.799  41.231  1.00 24.89  ? 379 LYS B O   1 
ATOM   6132  C  CB  . LYS B 1 400 ? -50.692 15.843  42.609  1.00 23.37  ? 379 LYS B CB  1 
ATOM   6133  C  CG  . LYS B 1 400 ? -51.602 14.635  42.745  1.00 22.33  ? 379 LYS B CG  1 
ATOM   6134  C  CD  . LYS B 1 400 ? -51.513 14.117  44.197  1.00 26.27  ? 379 LYS B CD  1 
ATOM   6135  C  CE  . LYS B 1 400 ? -52.292 12.816  44.345  1.00 27.63  ? 379 LYS B CE  1 
ATOM   6136  N  NZ  . LYS B 1 400 ? -51.979 12.079  45.604  1.00 31.87  ? 379 LYS B NZ  1 
ATOM   6137  N  N   . ILE B 1 401 ? -48.421 17.524  41.136  1.00 22.12  ? 380 ILE B N   1 
ATOM   6138  C  CA  . ILE B 1 401 ? -47.513 18.660  40.974  1.00 23.19  ? 380 ILE B CA  1 
ATOM   6139  C  C   . ILE B 1 401 ? -47.778 19.394  39.655  1.00 24.87  ? 380 ILE B C   1 
ATOM   6140  O  O   . ILE B 1 401 ? -47.876 20.628  39.621  1.00 21.31  ? 380 ILE B O   1 
ATOM   6141  C  CB  . ILE B 1 401 ? -46.047 18.178  41.088  1.00 20.29  ? 380 ILE B CB  1 
ATOM   6142  C  CG1 . ILE B 1 401 ? -45.782 17.752  42.550  1.00 26.04  ? 380 ILE B CG1 1 
ATOM   6143  C  CG2 . ILE B 1 401 ? -45.039 19.282  40.581  1.00 21.57  ? 380 ILE B CG2 1 
ATOM   6144  C  CD1 . ILE B 1 401 ? -44.338 17.421  42.859  1.00 39.96  ? 380 ILE B CD1 1 
ATOM   6145  N  N   . ALA B 1 402 ? -47.921 18.647  38.549  1.00 22.14  ? 381 ALA B N   1 
ATOM   6146  C  CA  . ALA B 1 402 ? -48.147 19.286  37.252  1.00 21.69  ? 381 ALA B CA  1 
ATOM   6147  C  C   . ALA B 1 402 ? -49.438 20.099  37.237  1.00 19.75  ? 381 ALA B C   1 
ATOM   6148  O  O   . ALA B 1 402 ? -49.451 21.239  36.758  1.00 21.88  ? 381 ALA B O   1 
ATOM   6149  C  CB  . ALA B 1 402 ? -48.159 18.229  36.137  1.00 21.63  ? 381 ALA B CB  1 
ATOM   6150  N  N   . VAL B 1 403 ? -50.535 19.528  37.743  1.00 19.33  ? 382 VAL B N   1 
ATOM   6151  C  CA  . VAL B 1 403 ? -51.831 20.208  37.708  1.00 20.84  ? 382 VAL B CA  1 
ATOM   6152  C  C   . VAL B 1 403 ? -51.825 21.386  38.658  1.00 22.00  ? 382 VAL B C   1 
ATOM   6153  O  O   . VAL B 1 403 ? -52.470 22.414  38.395  1.00 24.74  ? 382 VAL B O   1 
ATOM   6154  C  CB  . VAL B 1 403 ? -52.959 19.213  38.045  1.00 24.85  ? 382 VAL B CB  1 
ATOM   6155  C  CG1 . VAL B 1 403 ? -54.279 19.912  38.237  1.00 31.39  ? 382 VAL B CG1 1 
ATOM   6156  C  CG2 . VAL B 1 403 ? -53.123 18.208  36.902  1.00 28.49  ? 382 VAL B CG2 1 
ATOM   6157  N  N   . THR B 1 404 ? -51.084 21.271  39.752  1.00 22.63  ? 383 THR B N   1 
ATOM   6158  C  CA  . THR B 1 404 ? -50.936 22.411  40.663  1.00 22.22  ? 383 THR B CA  1 
ATOM   6159  C  C   . THR B 1 404 ? -50.216 23.564  39.972  1.00 22.79  ? 383 THR B C   1 
ATOM   6160  O  O   . THR B 1 404 ? -50.688 24.713  40.006  1.00 23.67  ? 383 THR B O   1 
ATOM   6161  C  CB  . THR B 1 404 ? -50.208 21.973  41.934  1.00 21.21  ? 383 THR B CB  1 
ATOM   6162  O  OG1 . THR B 1 404 ? -50.992 20.972  42.625  1.00 25.63  ? 383 THR B OG1 1 
ATOM   6163  C  CG2 . THR B 1 404 ? -49.980 23.182  42.882  1.00 22.77  ? 383 THR B CG2 1 
ATOM   6164  N  N   . ALA B 1 405 ? -49.101 23.277  39.290  1.00 20.69  ? 384 ALA B N   1 
ATOM   6165  C  CA  . ALA B 1 405 ? -48.389 24.335  38.569  1.00 21.13  ? 384 ALA B CA  1 
ATOM   6166  C  C   . ALA B 1 405 ? -49.225 24.886  37.428  1.00 22.90  ? 384 ALA B C   1 
ATOM   6167  O  O   . ALA B 1 405 ? -49.283 26.107  37.218  1.00 20.60  ? 384 ALA B O   1 
ATOM   6168  C  CB  . ALA B 1 405 ? -47.044 23.820  38.031  1.00 21.28  ? 384 ALA B CB  1 
ATOM   6169  N  N   . LEU B 1 406 ? -49.881 24.001  36.670  1.00 21.06  ? 385 LEU B N   1 
ATOM   6170  C  CA  . LEU B 1 406 ? -50.635 24.466  35.508  1.00 20.31  ? 385 LEU B CA  1 
ATOM   6171  C  C   . LEU B 1 406 ? -51.856 25.302  35.913  1.00 21.34  ? 385 LEU B C   1 
ATOM   6172  O  O   . LEU B 1 406 ? -52.177 26.299  35.249  1.00 22.68  ? 385 LEU B O   1 
ATOM   6173  C  CB  . LEU B 1 406 ? -51.061 23.262  34.668  1.00 18.79  ? 385 LEU B CB  1 
ATOM   6174  C  CG  . LEU B 1 406 ? -51.760 23.581  33.344  1.00 18.26  ? 385 LEU B CG  1 
ATOM   6175  C  CD1 . LEU B 1 406 ? -50.915 24.541  32.492  1.00 18.87  ? 385 LEU B CD1 1 
ATOM   6176  C  CD2 . LEU B 1 406 ? -51.991 22.219  32.603  1.00 20.75  ? 385 LEU B CD2 1 
ATOM   6177  N  N   . SER B 1 407 ? -52.565 24.893  36.971  1.00 22.62  ? 386 SER B N   1 
ATOM   6178  C  CA  . SER B 1 407 ? -53.684 25.687  37.479  1.00 23.83  ? 386 SER B CA  1 
ATOM   6179  C  C   . SER B 1 407 ? -53.215 27.060  37.951  1.00 27.02  ? 386 SER B C   1 
ATOM   6180  O  O   . SER B 1 407 ? -53.880 28.073  37.699  1.00 23.95  ? 386 SER B O   1 
ATOM   6181  C  CB  . SER B 1 407 ? -54.378 24.965  38.637  1.00 25.82  ? 386 SER B CB  1 
ATOM   6182  O  OG  . SER B 1 407 ? -54.914 23.736  38.200  1.00 35.18  ? 386 SER B OG  1 
ATOM   6183  N  N   . ALA B 1 408 ? -52.074 27.114  38.638  1.00 23.12  ? 387 ALA B N   1 
ATOM   6184  C  CA  . ALA B 1 408 ? -51.545 28.414  39.048  1.00 22.28  ? 387 ALA B CA  1 
ATOM   6185  C  C   . ALA B 1 408 ? -51.273 29.291  37.835  1.00 25.90  ? 387 ALA B C   1 
ATOM   6186  O  O   . ALA B 1 408 ? -51.589 30.492  37.839  1.00 24.13  ? 387 ALA B O   1 
ATOM   6187  C  CB  . ALA B 1 408 ? -50.284 28.226  39.896  1.00 24.64  ? 387 ALA B CB  1 
ATOM   6188  N  N   . ALA B 1 409 ? -50.749 28.700  36.750  1.00 21.76  ? 388 ALA B N   1 
ATOM   6189  C  CA  . ALA B 1 409 ? -50.491 29.491  35.548  1.00 22.43  ? 388 ALA B CA  1 
ATOM   6190  C  C   . ALA B 1 409 ? -51.797 29.935  34.897  1.00 22.84  ? 388 ALA B C   1 
ATOM   6191  O  O   . ALA B 1 409 ? -51.901 31.064  34.393  1.00 22.63  ? 388 ALA B O   1 
ATOM   6192  C  CB  . ALA B 1 409 ? -49.665 28.683  34.546  1.00 21.00  ? 388 ALA B CB  1 
ATOM   6193  N  N   . VAL B 1 410 ? -52.786 29.051  34.864  1.00 21.15  ? 389 VAL B N   1 
ATOM   6194  C  CA  . VAL B 1 410 ? -54.073 29.407  34.259  1.00 20.32  ? 389 VAL B CA  1 
ATOM   6195  C  C   . VAL B 1 410 ? -54.687 30.602  34.989  1.00 24.92  ? 389 VAL B C   1 
ATOM   6196  O  O   . VAL B 1 410 ? -55.190 31.542  34.364  1.00 23.74  ? 389 VAL B O   1 
ATOM   6197  C  CB  . VAL B 1 410 ? -55.018 28.203  34.278  1.00 20.47  ? 389 VAL B CB  1 
ATOM   6198  C  CG1 . VAL B 1 410 ? -56.457 28.637  33.985  1.00 22.32  ? 389 VAL B CG1 1 
ATOM   6199  C  CG2 . VAL B 1 410 ? -54.519 27.088  33.308  1.00 20.94  ? 389 VAL B CG2 1 
ATOM   6200  N  N   . GLU B 1 411 ? -54.694 30.561  36.320  1.00 20.80  ? 390 GLU B N   1 
ATOM   6201  C  CA  . GLU B 1 411 ? -55.284 31.681  37.074  1.00 20.47  ? 390 GLU B CA  1 
ATOM   6202  C  C   . GLU B 1 411 ? -54.571 33.002  36.786  1.00 24.92  ? 390 GLU B C   1 
ATOM   6203  O  O   . GLU B 1 411 ? -55.221 34.049  36.641  1.00 23.23  ? 390 GLU B O   1 
ATOM   6204  C  CB  . GLU B 1 411 ? -55.243 31.390  38.571  1.00 30.40  ? 390 GLU B CB  1 
ATOM   6205  C  CG  . GLU B 1 411 ? -56.143 30.217  38.941  1.00 42.31  ? 390 GLU B CG  1 
ATOM   6206  C  CD  . GLU B 1 411 ? -56.671 30.265  40.356  1.00 59.49  ? 390 GLU B CD  1 
ATOM   6207  O  OE1 . GLU B 1 411 ? -56.161 31.069  41.174  1.00 68.64  ? 390 GLU B OE1 1 
ATOM   6208  O  OE2 . GLU B 1 411 ? -57.616 29.491  40.636  1.00 45.46  ? 390 GLU B OE2 1 
ATOM   6209  N  N   . ALA B 1 412 ? -53.240 32.983  36.753  1.00 21.60  ? 391 ALA B N   1 
ATOM   6210  C  CA  . ALA B 1 412 ? -52.471 34.211  36.485  1.00 21.49  ? 391 ALA B CA  1 
ATOM   6211  C  C   . ALA B 1 412 ? -52.615 34.681  35.029  1.00 26.68  ? 391 ALA B C   1 
ATOM   6212  O  O   . ALA B 1 412 ? -52.803 35.878  34.769  1.00 23.47  ? 391 ALA B O   1 
ATOM   6213  C  CB  . ALA B 1 412 ? -51.000 33.978  36.855  1.00 20.83  ? 391 ALA B CB  1 
ATOM   6214  N  N   . LEU B 1 413 ? -52.572 33.762  34.059  1.00 20.81  ? 392 LEU B N   1 
ATOM   6215  C  CA  . LEU B 1 413 ? -52.686 34.194  32.666  1.00 20.14  ? 392 LEU B CA  1 
ATOM   6216  C  C   . LEU B 1 413 ? -54.080 34.745  32.335  1.00 22.29  ? 392 LEU B C   1 
ATOM   6217  O  O   . LEU B 1 413 ? -54.224 35.510  31.371  1.00 22.63  ? 392 LEU B O   1 
ATOM   6218  C  CB  . LEU B 1 413 ? -52.384 33.017  31.732  1.00 24.63  ? 392 LEU B CB  1 
ATOM   6219  C  CG  . LEU B 1 413 ? -50.943 32.495  31.667  1.00 25.51  ? 392 LEU B CG  1 
ATOM   6220  C  CD1 . LEU B 1 413 ? -50.984 31.095  31.023  1.00 21.29  ? 392 LEU B CD1 1 
ATOM   6221  C  CD2 . LEU B 1 413 ? -50.119 33.468  30.836  1.00 23.99  ? 392 LEU B CD2 1 
ATOM   6222  N  N   . ALA B 1 414 ? -55.119 34.265  33.024  1.00 19.39  ? 393 ALA B N   1 
ATOM   6223  C  CA  . ALA B 1 414 ? -56.490 34.656  32.736  1.00 18.17  ? 393 ALA B CA  1 
ATOM   6224  C  C   . ALA B 1 414 ? -56.754 36.125  33.092  1.00 18.86  ? 393 ALA B C   1 
ATOM   6225  O  O   . ALA B 1 414 ? -57.692 36.708  32.558  1.00 24.94  ? 393 ALA B O   1 
ATOM   6226  C  CB  . ALA B 1 414 ? -57.487 33.764  33.512  1.00 18.24  ? 393 ALA B CB  1 
ATOM   6227  N  N   . ARG B 1 415 ? -55.991 36.694  34.010  1.00 22.19  ? 394 ARG B N   1 
ATOM   6228  C  CA  . ARG B 1 415 ? -56.308 38.039  34.501  1.00 20.24  ? 394 ARG B CA  1 
ATOM   6229  C  C   . ARG B 1 415 ? -56.375 39.035  33.350  1.00 23.23  ? 394 ARG B C   1 
ATOM   6230  O  O   . ARG B 1 415 ? -55.568 38.952  32.413  1.00 23.57  ? 394 ARG B O   1 
ATOM   6231  C  CB  . ARG B 1 415 ? -55.275 38.466  35.535  1.00 27.08  ? 394 ARG B CB  1 
ATOM   6232  C  CG  . ARG B 1 415 ? -55.480 37.656  36.811  1.00 27.09  ? 394 ARG B CG  1 
ATOM   6233  C  CD  . ARG B 1 415 ? -54.973 38.397  38.038  1.00 42.66  ? 394 ARG B CD  1 
ATOM   6234  N  NE  . ARG B 1 415 ? -53.638 37.934  38.391  1.00 65.82  ? 394 ARG B NE  1 
ATOM   6235  C  CZ  . ARG B 1 415 ? -53.391 36.938  39.232  1.00 58.28  ? 394 ARG B CZ  1 
ATOM   6236  N  NH1 . ARG B 1 415 ? -54.371 36.304  39.861  1.00 62.89  ? 394 ARG B NH1 1 
ATOM   6237  N  NH2 . ARG B 1 415 ? -52.131 36.568  39.447  1.00 57.29  ? 394 ARG B NH2 1 
ATOM   6238  N  N   . PRO B 1 416 ? -57.317 39.992  33.388  1.00 21.79  ? 395 PRO B N   1 
ATOM   6239  C  CA  . PRO B 1 416 ? -57.580 40.796  32.191  1.00 22.15  ? 395 PRO B CA  1 
ATOM   6240  C  C   . PRO B 1 416 ? -56.437 41.699  31.810  1.00 22.22  ? 395 PRO B C   1 
ATOM   6241  O  O   . PRO B 1 416 ? -56.359 42.064  30.634  1.00 23.62  ? 395 PRO B O   1 
ATOM   6242  C  CB  . PRO B 1 416 ? -58.845 41.603  32.559  1.00 25.26  ? 395 PRO B CB  1 
ATOM   6243  C  CG  . PRO B 1 416 ? -58.795 41.701  34.089  1.00 25.91  ? 395 PRO B CG  1 
ATOM   6244  C  CD  . PRO B 1 416 ? -58.237 40.316  34.497  1.00 23.27  ? 395 PRO B CD  1 
ATOM   6245  N  N   . GLU B 1 417 ? -55.523 42.031  32.724  1.00 20.87  ? 396 GLU B N   1 
ATOM   6246  C  CA  . GLU B 1 417 ? -54.392 42.864  32.323  1.00 22.19  ? 396 GLU B CA  1 
ATOM   6247  C  C   . GLU B 1 417 ? -53.351 42.110  31.492  1.00 27.03  ? 396 GLU B C   1 
ATOM   6248  O  O   . GLU B 1 417 ? -52.485 42.755  30.904  1.00 25.31  ? 396 GLU B O   1 
ATOM   6249  C  CB  . GLU B 1 417 ? -53.693 43.484  33.542  1.00 24.18  ? 396 GLU B CB  1 
ATOM   6250  C  CG  . GLU B 1 417 ? -53.112 42.481  34.514  1.00 25.28  ? 396 GLU B CG  1 
ATOM   6251  C  CD  . GLU B 1 417 ? -54.060 42.091  35.648  1.00 27.31  ? 396 GLU B CD  1 
ATOM   6252  O  OE1 . GLU B 1 417 ? -55.298 42.137  35.475  1.00 25.59  ? 396 GLU B OE1 1 
ATOM   6253  O  OE2 . GLU B 1 417 ? -53.555 41.710  36.721  1.00 31.58  ? 396 GLU B OE2 1 
ATOM   6254  N  N   . VAL B 1 418 ? -53.409 40.780  31.446  1.00 25.80  ? 397 VAL B N   1 
ATOM   6255  C  CA  . VAL B 1 418 ? -52.503 39.976  30.634  1.00 22.03  ? 397 VAL B CA  1 
ATOM   6256  C  C   . VAL B 1 418 ? -52.977 40.024  29.188  1.00 26.55  ? 397 VAL B C   1 
ATOM   6257  O  O   . VAL B 1 418 ? -54.098 39.612  28.877  1.00 27.45  ? 397 VAL B O   1 
ATOM   6258  C  CB  . VAL B 1 418 ? -52.439 38.525  31.152  1.00 21.26  ? 397 VAL B CB  1 
ATOM   6259  C  CG1 . VAL B 1 418 ? -51.448 37.700  30.277  1.00 25.00  ? 397 VAL B CG1 1 
ATOM   6260  C  CG2 . VAL B 1 418 ? -51.996 38.535  32.578  1.00 21.74  ? 397 VAL B CG2 1 
ATOM   6261  N  N   . ARG B 1 419 ? -52.132 40.541  28.299  1.00 23.45  ? 398 ARG B N   1 
ATOM   6262  C  CA  . ARG B 1 419 ? -52.498 40.671  26.889  1.00 22.38  ? 398 ARG B CA  1 
ATOM   6263  C  C   . ARG B 1 419 ? -51.705 39.628  26.110  1.00 24.07  ? 398 ARG B C   1 
ATOM   6264  O  O   . ARG B 1 419 ? -50.487 39.770  25.936  1.00 24.36  ? 398 ARG B O   1 
ATOM   6265  C  CB  . ARG B 1 419 ? -52.212 42.075  26.356  1.00 28.27  ? 398 ARG B CB  1 
ATOM   6266  C  CG  . ARG B 1 419 ? -52.772 43.220  27.261  1.00 37.96  ? 398 ARG B CG  1 
ATOM   6267  C  CD  . ARG B 1 419 ? -54.302 43.151  27.486  1.00 47.20  ? 398 ARG B CD  1 
ATOM   6268  N  NE  . ARG B 1 419 ? -54.771 44.092  28.515  1.00 50.73  ? 398 ARG B NE  1 
ATOM   6269  C  CZ  . ARG B 1 419 ? -55.007 45.387  28.303  1.00 61.69  ? 398 ARG B CZ  1 
ATOM   6270  N  NH1 . ARG B 1 419 ? -54.810 45.939  27.114  1.00 55.80  ? 398 ARG B NH1 1 
ATOM   6271  N  NH2 . ARG B 1 419 ? -55.445 46.151  29.312  1.00 43.85  ? 398 ARG B NH2 1 
ATOM   6272  N  N   . ILE B 1 420 ? -52.410 38.600  25.649  1.00 26.19  ? 399 ILE B N   1 
ATOM   6273  C  CA  . ILE B 1 420 ? -51.814 37.439  24.990  1.00 28.02  ? 399 ILE B CA  1 
ATOM   6274  C  C   . ILE B 1 420 ? -51.795 37.723  23.494  1.00 23.80  ? 399 ILE B C   1 
ATOM   6275  O  O   . ILE B 1 420 ? -52.837 38.012  22.905  1.00 26.53  ? 399 ILE B O   1 
ATOM   6276  C  CB  . ILE B 1 420 ? -52.616 36.165  25.302  1.00 22.23  ? 399 ILE B CB  1 
ATOM   6277  C  CG1 . ILE B 1 420 ? -52.674 35.917  26.810  1.00 24.46  ? 399 ILE B CG1 1 
ATOM   6278  C  CG2 . ILE B 1 420 ? -52.049 34.920  24.550  1.00 21.30  ? 399 ILE B CG2 1 
ATOM   6279  C  CD1 . ILE B 1 420 ? -53.728 34.870  27.215  1.00 26.46  ? 399 ILE B CD1 1 
ATOM   6280  N  N   . SER B 1 421 ? -50.618 37.665  22.882  1.00 23.87  ? 400 SER B N   1 
ATOM   6281  C  CA  . SER B 1 421 ? -50.537 37.964  21.457  1.00 26.77  ? 400 SER B CA  1 
ATOM   6282  C  C   . SER B 1 421 ? -51.394 36.982  20.649  1.00 30.34  ? 400 SER B C   1 
ATOM   6283  O  O   . SER B 1 421 ? -51.416 35.785  20.933  1.00 29.41  ? 400 SER B O   1 
ATOM   6284  C  CB  . SER B 1 421 ? -49.083 37.890  20.983  1.00 30.48  ? 400 SER B CB  1 
ATOM   6285  O  OG  . SER B 1 421 ? -49.062 38.005  19.566  1.00 28.80  ? 400 SER B OG  1 
ATOM   6286  N  N   . ALA B 1 422 ? -52.082 37.483  19.621  1.00 26.97  ? 401 ALA B N   1 
ATOM   6287  C  CA  . ALA B 1 422 ? -52.891 36.619  18.758  1.00 32.10  ? 401 ALA B CA  1 
ATOM   6288  C  C   . ALA B 1 422 ? -52.277 36.436  17.365  1.00 23.72  ? 401 ALA B C   1 
ATOM   6289  O  O   . ALA B 1 422 ? -52.955 35.950  16.439  1.00 26.31  ? 401 ALA B O   1 
ATOM   6290  C  CB  . ALA B 1 422 ? -54.319 37.157  18.642  1.00 30.62  ? 401 ALA B CB  1 
ATOM   6291  N  N   . GLU B 1 423 ? -51.017 36.822  17.176  1.00 24.34  ? 402 GLU B N   1 
ATOM   6292  C  CA  . GLU B 1 423 ? -50.420 36.649  15.859  1.00 25.58  ? 402 GLU B CA  1 
ATOM   6293  C  C   . GLU B 1 423 ? -50.152 35.174  15.602  1.00 27.13  ? 402 GLU B C   1 
ATOM   6294  O  O   . GLU B 1 423 ? -50.086 34.347  16.523  1.00 24.59  ? 402 GLU B O   1 
ATOM   6295  C  CB  . GLU B 1 423 ? -49.117 37.454  15.724  1.00 23.81  ? 402 GLU B CB  1 
ATOM   6296  C  CG  . GLU B 1 423 ? -49.310 38.910  16.149  1.00 25.78  ? 402 GLU B CG  1 
ATOM   6297  C  CD  . GLU B 1 423 ? -48.529 39.944  15.304  1.00 43.12  ? 402 GLU B CD  1 
ATOM   6298  O  OE1 . GLU B 1 423 ? -47.962 39.601  14.229  1.00 31.55  ? 402 GLU B OE1 1 
ATOM   6299  O  OE2 . GLU B 1 423 ? -48.490 41.125  15.742  1.00 41.82  ? 402 GLU B OE2 1 
ATOM   6300  N  N   . ALA B 1 424 ? -49.968 34.851  14.325  1.00 23.79  ? 403 ALA B N   1 
ATOM   6301  C  CA  . ALA B 1 424 ? -49.992 33.449  13.919  1.00 24.36  ? 403 ALA B CA  1 
ATOM   6302  C  C   . ALA B 1 424 ? -48.871 32.643  14.575  1.00 22.40  ? 403 ALA B C   1 
ATOM   6303  O  O   . ALA B 1 424 ? -49.095 31.507  15.000  1.00 24.98  ? 403 ALA B O   1 
ATOM   6304  C  CB  . ALA B 1 424 ? -49.917 33.343  12.395  1.00 28.29  ? 403 ALA B CB  1 
ATOM   6305  N  N   . ILE B 1 425 ? -47.666 33.213  14.685  1.00 20.60  ? 404 ILE B N   1 
ATOM   6306  C  CA  . ILE B 1 425 ? -46.580 32.501  15.353  1.00 25.67  ? 404 ILE B CA  1 
ATOM   6307  C  C   . ILE B 1 425 ? -46.795 32.320  16.844  1.00 26.86  ? 404 ILE B C   1 
ATOM   6308  O  O   . ILE B 1 425 ? -46.094 31.500  17.459  1.00 25.54  ? 404 ILE B O   1 
ATOM   6309  C  CB  . ILE B 1 425 ? -45.217 33.190  15.150  1.00 24.84  ? 404 ILE B CB  1 
ATOM   6310  C  CG1 . ILE B 1 425 ? -45.242 34.651  15.626  1.00 24.06  ? 404 ILE B CG1 1 
ATOM   6311  C  CG2 . ILE B 1 425 ? -44.731 32.980  13.725  1.00 30.16  ? 404 ILE B CG2 1 
ATOM   6312  C  CD1 . ILE B 1 425 ? -43.794 35.214  15.724  1.00 30.62  ? 404 ILE B CD1 1 
ATOM   6313  N  N   . ASP B 1 426 ? -47.755 33.043  17.449  1.00 23.08  ? 405 ASP B N   1 
ATOM   6314  C  CA  . ASP B 1 426 ? -48.044 32.865  18.869  1.00 22.85  ? 405 ASP B CA  1 
ATOM   6315  C  C   . ASP B 1 426 ? -49.129 31.836  19.165  1.00 25.15  ? 405 ASP B C   1 
ATOM   6316  O  O   . ASP B 1 426 ? -49.143 31.260  20.265  1.00 24.20  ? 405 ASP B O   1 
ATOM   6317  C  CB  . ASP B 1 426 ? -48.463 34.207  19.501  1.00 22.26  ? 405 ASP B CB  1 
ATOM   6318  C  CG  . ASP B 1 426 ? -47.400 35.273  19.359  1.00 24.46  ? 405 ASP B CG  1 
ATOM   6319  O  OD1 . ASP B 1 426 ? -46.309 35.142  19.961  1.00 26.62  ? 405 ASP B OD1 1 
ATOM   6320  O  OD2 . ASP B 1 426 ? -47.626 36.242  18.601  1.00 26.65  ? 405 ASP B OD2 1 
ATOM   6321  N  N   . ILE B 1 427 ? -50.040 31.611  18.224  1.00 24.19  ? 406 ILE B N   1 
ATOM   6322  C  CA  . ILE B 1 427 ? -51.252 30.830  18.457  1.00 25.59  ? 406 ILE B CA  1 
ATOM   6323  C  C   . ILE B 1 427 ? -51.176 29.448  17.813  1.00 35.22  ? 406 ILE B C   1 
ATOM   6324  O  O   . ILE B 1 427 ? -51.768 28.499  18.335  1.00 32.53  ? 406 ILE B O   1 
ATOM   6325  C  CB  . ILE B 1 427 ? -52.479 31.601  17.926  1.00 32.60  ? 406 ILE B CB  1 
ATOM   6326  C  CG1 . ILE B 1 427 ? -52.643 32.860  18.736  1.00 28.82  ? 406 ILE B CG1 1 
ATOM   6327  C  CG2 . ILE B 1 427 ? -53.787 30.763  18.018  1.00 33.19  ? 406 ILE B CG2 1 
ATOM   6328  C  CD1 . ILE B 1 427 ? -52.938 32.564  20.180  1.00 27.67  ? 406 ILE B CD1 1 
ATOM   6329  N  N   . ASN B 1 428 ? -50.481 29.314  16.699  1.00 21.79  ? 407 ASN B N   1 
ATOM   6330  C  CA  . ASN B 1 428 ? -50.434 28.040  15.995  1.00 25.76  ? 407 ASN B CA  1 
ATOM   6331  C  C   . ASN B 1 428 ? -49.238 27.195  16.420  1.00 28.18  ? 407 ASN B C   1 
ATOM   6332  O  O   . ASN B 1 428 ? -48.230 27.696  16.923  1.00 27.30  ? 407 ASN B O   1 
ATOM   6333  C  CB  . ASN B 1 428 ? -50.394 28.302  14.502  1.00 30.54  ? 407 ASN B CB  1 
ATOM   6334  C  CG  . ASN B 1 428 ? -51.679 28.907  14.020  1.00 34.37  ? 407 ASN B CG  1 
ATOM   6335  O  OD1 . ASN B 1 428 ? -52.669 28.194  13.857  1.00 30.92  ? 407 ASN B OD1 1 
ATOM   6336  N  ND2 . ASN B 1 428 ? -51.689 30.223  13.810  1.00 30.21  ? 407 ASN B ND2 1 
ATOM   6337  N  N   . TYR B 1 429 ? -49.366 25.883  16.225  1.00 25.23  ? 408 TYR B N   1 
ATOM   6338  C  CA  . TYR B 1 429 ? -48.288 24.984  16.608  1.00 25.48  ? 408 TYR B CA  1 
ATOM   6339  C  C   . TYR B 1 429 ? -48.239 23.841  15.602  1.00 22.44  ? 408 TYR B C   1 
ATOM   6340  O  O   . TYR B 1 429 ? -49.265 23.408  15.080  1.00 22.91  ? 408 TYR B O   1 
ATOM   6341  C  CB  . TYR B 1 429 ? -48.441 24.412  18.046  1.00 25.71  ? 408 TYR B CB  1 
ATOM   6342  C  CG  . TYR B 1 429 ? -49.784 23.811  18.329  1.00 25.28  ? 408 TYR B CG  1 
ATOM   6343  C  CD1 . TYR B 1 429 ? -50.880 24.620  18.713  1.00 22.76  ? 408 TYR B CD1 1 
ATOM   6344  C  CD2 . TYR B 1 429 ? -49.989 22.434  18.205  1.00 24.32  ? 408 TYR B CD2 1 
ATOM   6345  C  CE1 . TYR B 1 429 ? -52.121 24.072  18.943  1.00 28.34  ? 408 TYR B CE1 1 
ATOM   6346  C  CE2 . TYR B 1 429 ? -51.257 21.876  18.438  1.00 21.55  ? 408 TYR B CE2 1 
ATOM   6347  C  CZ  . TYR B 1 429 ? -52.298 22.695  18.806  1.00 29.97  ? 408 TYR B CZ  1 
ATOM   6348  O  OH  . TYR B 1 429 ? -53.517 22.117  19.035  1.00 35.70  ? 408 TYR B OH  1 
ATOM   6349  N  N   . SER B 1 430 ? -47.033 23.367  15.348  1.00 27.15  ? 409 SER B N   1 
ATOM   6350  C  CA  . SER B 1 430 ? -46.837 22.228  14.465  1.00 28.36  ? 409 SER B CA  1 
ATOM   6351  C  C   . SER B 1 430 ? -47.111 20.906  15.181  1.00 28.86  ? 409 SER B C   1 
ATOM   6352  O  O   . SER B 1 430 ? -46.715 20.703  16.330  1.00 28.66  ? 409 SER B O   1 
ATOM   6353  C  CB  . SER B 1 430 ? -45.396 22.220  13.950  1.00 27.27  ? 409 SER B CB  1 
ATOM   6354  O  OG  . SER B 1 430 ? -45.200 21.083  13.114  1.00 28.13  ? 409 SER B OG  1 
ATOM   6355  N  N   . MET B 1 431 ? -47.714 19.974  14.466  1.00 20.19  ? 410 MET B N   1 
ATOM   6356  C  CA  . MET B 1 431 ? -47.894 18.629  14.978  1.00 22.82  ? 410 MET B CA  1 
ATOM   6357  C  C   . MET B 1 431 ? -46.740 17.715  14.585  1.00 23.22  ? 410 MET B C   1 
ATOM   6358  O  O   . MET B 1 431 ? -46.725 16.558  14.983  1.00 21.02  ? 410 MET B O   1 
ATOM   6359  C  CB  . MET B 1 431 ? -49.241 18.047  14.473  1.00 23.80  ? 410 MET B CB  1 
ATOM   6360  C  CG  . MET B 1 431 ? -50.512 18.660  15.127  1.00 27.80  ? 410 MET B CG  1 
ATOM   6361  S  SD  . MET B 1 431 ? -50.590 18.364  16.881  1.00 35.75  ? 410 MET B SD  1 
ATOM   6362  C  CE  . MET B 1 431 ? -51.351 16.748  16.971  1.00 28.29  ? 410 MET B CE  1 
ATOM   6363  N  N   . THR B 1 432 ? -45.768 18.182  13.795  1.00 22.23  ? 411 THR B N   1 
ATOM   6364  C  CA  . THR B 1 432 ? -44.811 17.237  13.233  1.00 24.28  ? 411 THR B CA  1 
ATOM   6365  C  C   . THR B 1 432 ? -43.441 17.295  13.913  1.00 26.67  ? 411 THR B C   1 
ATOM   6366  O  O   . THR B 1 432 ? -42.506 16.646  13.450  1.00 34.87  ? 411 THR B O   1 
ATOM   6367  C  CB  . THR B 1 432 ? -44.680 17.446  11.725  1.00 29.29  ? 411 THR B CB  1 
ATOM   6368  O  OG1 . THR B 1 432 ? -44.301 18.810  11.464  1.00 29.95  ? 411 THR B OG1 1 
ATOM   6369  C  CG2 . THR B 1 432 ? -46.022 17.094  10.988  1.00 25.02  ? 411 THR B CG2 1 
ATOM   6370  N  N   A GLU B 1 433 ? -43.313 18.050  15.001  0.50 24.80  ? 412 GLU B N   1 
ATOM   6371  N  N   B GLU B 1 433 ? -43.318 18.064  14.990  0.50 24.79  ? 412 GLU B N   1 
ATOM   6372  C  CA  A GLU B 1 433 ? -42.069 18.176  15.753  0.50 23.96  ? 412 GLU B CA  1 
ATOM   6373  C  CA  B GLU B 1 433 ? -42.097 18.228  15.771  0.50 24.03  ? 412 GLU B CA  1 
ATOM   6374  C  C   A GLU B 1 433 ? -42.350 17.971  17.235  0.50 28.66  ? 412 GLU B C   1 
ATOM   6375  C  C   B GLU B 1 433 ? -42.422 17.869  17.212  0.50 28.66  ? 412 GLU B C   1 
ATOM   6376  O  O   A GLU B 1 433 ? -43.312 18.525  17.779  0.50 27.65  ? 412 GLU B O   1 
ATOM   6377  O  O   B GLU B 1 433 ? -43.511 18.188  17.699  0.50 27.17  ? 412 GLU B O   1 
ATOM   6378  C  CB  A GLU B 1 433 ? -41.421 19.558  15.535  0.50 30.90  ? 412 GLU B CB  1 
ATOM   6379  C  CB  B GLU B 1 433 ? -41.588 19.691  15.674  0.50 30.26  ? 412 GLU B CB  1 
ATOM   6380  C  CG  A GLU B 1 433 ? -40.783 19.752  14.153  0.50 31.75  ? 412 GLU B CG  1 
ATOM   6381  C  CG  B GLU B 1 433 ? -40.375 20.055  16.517  0.50 29.28  ? 412 GLU B CG  1 
ATOM   6382  C  CD  A GLU B 1 433 ? -41.772 20.126  13.051  0.50 36.26  ? 412 GLU B CD  1 
ATOM   6383  C  CD  B GLU B 1 433 ? -39.941 21.509  16.294  0.50 36.06  ? 412 GLU B CD  1 
ATOM   6384  O  OE1 A GLU B 1 433 ? -42.513 21.135  13.189  0.50 31.20  ? 412 GLU B OE1 1 
ATOM   6385  O  OE1 B GLU B 1 433 ? -40.544 22.185  15.434  0.50 51.12  ? 412 GLU B OE1 1 
ATOM   6386  O  OE2 A GLU B 1 433 ? -41.783 19.414  12.016  0.50 37.16  ? 412 GLU B OE2 1 
ATOM   6387  O  OE2 B GLU B 1 433 ? -39.017 21.982  16.988  0.50 42.59  ? 412 GLU B OE2 1 
ATOM   6388  N  N   . ILE B 1 434 ? -41.494 17.187  17.885  1.00 23.51  ? 413 ILE B N   1 
ATOM   6389  C  CA  . ILE B 1 434 ? -41.648 16.805  19.281  1.00 19.20  ? 413 ILE B CA  1 
ATOM   6390  C  C   . ILE B 1 434 ? -40.544 17.537  20.056  1.00 27.21  ? 413 ILE B C   1 
ATOM   6391  O  O   . ILE B 1 434 ? -39.405 17.587  19.584  1.00 27.59  ? 413 ILE B O   1 
ATOM   6392  C  CB  . ILE B 1 434 ? -41.538 15.276  19.421  1.00 26.73  ? 413 ILE B CB  1 
ATOM   6393  C  CG1 . ILE B 1 434 ? -42.749 14.606  18.736  1.00 29.13  ? 413 ILE B CG1 1 
ATOM   6394  C  CG2 . ILE B 1 434 ? -41.353 14.850  20.862  1.00 35.29  ? 413 ILE B CG2 1 
ATOM   6395  C  CD1 . ILE B 1 434 ? -42.580 13.125  18.383  1.00 38.14  ? 413 ILE B CD1 1 
ATOM   6396  N  N   . LEU B 1 435 ? -40.886 18.176  21.177  1.00 21.29  ? 414 LEU B N   1 
ATOM   6397  C  CA  . LEU B 1 435 ? -42.225 18.448  21.713  1.00 23.44  ? 414 LEU B CA  1 
ATOM   6398  C  C   . LEU B 1 435 ? -42.858 19.606  20.941  1.00 26.84  ? 414 LEU B C   1 
ATOM   6399  O  O   . LEU B 1 435 ? -42.153 20.389  20.318  1.00 28.01  ? 414 LEU B O   1 
ATOM   6400  C  CB  . LEU B 1 435 ? -42.146 18.807  23.220  1.00 22.47  ? 414 LEU B CB  1 
ATOM   6401  C  CG  . LEU B 1 435 ? -41.622 17.687  24.100  1.00 19.88  ? 414 LEU B CG  1 
ATOM   6402  C  CD1 . LEU B 1 435 ? -41.230 18.221  25.493  1.00 23.72  ? 414 LEU B CD1 1 
ATOM   6403  C  CD2 . LEU B 1 435 ? -42.683 16.577  24.232  1.00 19.35  ? 414 LEU B CD2 1 
ATOM   6404  N  N   . ALA B 1 436 ? -44.179 19.728  21.021  1.00 19.29  ? 415 ALA B N   1 
ATOM   6405  C  CA  . ALA B 1 436 ? -44.915 20.766  20.316  1.00 22.10  ? 415 ALA B CA  1 
ATOM   6406  C  C   . ALA B 1 436 ? -45.051 22.002  21.186  1.00 21.89  ? 415 ALA B C   1 
ATOM   6407  O  O   . ALA B 1 436 ? -45.274 21.889  22.400  1.00 24.06  ? 415 ALA B O   1 
ATOM   6408  C  CB  . ALA B 1 436 ? -46.310 20.252  19.943  1.00 24.35  ? 415 ALA B CB  1 
ATOM   6409  N  N   . ARG B 1 437 ? -44.922 23.175  20.562  1.00 26.68  ? 416 ARG B N   1 
ATOM   6410  C  CA  . ARG B 1 437 ? -45.363 24.417  21.197  1.00 25.69  ? 416 ARG B CA  1 
ATOM   6411  C  C   . ARG B 1 437 ? -45.485 25.490  20.126  1.00 24.32  ? 416 ARG B C   1 
ATOM   6412  O  O   . ARG B 1 437 ? -44.854 25.396  19.069  1.00 25.39  ? 416 ARG B O   1 
ATOM   6413  C  CB  . ARG B 1 437 ? -44.384 24.863  22.302  1.00 25.09  ? 416 ARG B CB  1 
ATOM   6414  C  CG  . ARG B 1 437 ? -42.967 25.126  21.797  1.00 24.86  ? 416 ARG B CG  1 
ATOM   6415  C  CD  . ARG B 1 437 ? -42.126 25.772  22.908  1.00 24.39  ? 416 ARG B CD  1 
ATOM   6416  N  NE  . ARG B 1 437 ? -40.755 26.016  22.463  1.00 24.66  ? 416 ARG B NE  1 
ATOM   6417  C  CZ  . ARG B 1 437 ? -40.349 27.123  21.853  1.00 32.92  ? 416 ARG B CZ  1 
ATOM   6418  N  NH1 . ARG B 1 437 ? -41.210 28.045  21.438  1.00 29.78  ? 416 ARG B NH1 1 
ATOM   6419  N  NH2 . ARG B 1 437 ? -39.042 27.313  21.657  1.00 32.85  ? 416 ARG B NH2 1 
ATOM   6420  N  N   . PRO B 1 438 ? -46.250 26.548  20.381  1.00 27.43  ? 417 PRO B N   1 
ATOM   6421  C  CA  . PRO B 1 438 ? -46.182 27.714  19.486  1.00 28.51  ? 417 PRO B CA  1 
ATOM   6422  C  C   . PRO B 1 438 ? -44.738 28.149  19.304  1.00 28.02  ? 417 PRO B C   1 
ATOM   6423  O  O   . PRO B 1 438 ? -43.972 28.222  20.277  1.00 28.56  ? 417 PRO B O   1 
ATOM   6424  C  CB  . PRO B 1 438 ? -47.020 28.775  20.214  1.00 33.52  ? 417 PRO B CB  1 
ATOM   6425  C  CG  . PRO B 1 438 ? -47.926 28.005  21.094  1.00 28.76  ? 417 PRO B CG  1 
ATOM   6426  C  CD  . PRO B 1 438 ? -47.167 26.751  21.514  1.00 27.63  ? 417 PRO B CD  1 
ATOM   6427  N  N   . LYS B 1 439 ? -44.362 28.418  18.036  1.00 28.02  ? 418 LYS B N   1 
ATOM   6428  C  CA  . LYS B 1 439 ? -42.977 28.740  17.688  1.00 31.76  ? 418 LYS B CA  1 
ATOM   6429  C  C   . LYS B 1 439 ? -42.448 29.909  18.491  1.00 35.12  ? 418 LYS B C   1 
ATOM   6430  O  O   . LYS B 1 439 ? -41.262 29.955  18.828  1.00 35.54  ? 418 LYS B O   1 
ATOM   6431  C  CB  . LYS B 1 439 ? -42.858 29.062  16.194  1.00 37.07  ? 418 LYS B CB  1 
ATOM   6432  C  CG  . LYS B 1 439 ? -42.674 27.818  15.302  1.00 50.92  ? 418 LYS B CG  1 
ATOM   6433  C  CD  . LYS B 1 439 ? -42.650 28.158  13.804  1.00 67.36  ? 418 LYS B CD  1 
ATOM   6434  C  CE  . LYS B 1 439 ? -42.472 26.899  12.909  1.00 54.22  ? 418 LYS B CE  1 
ATOM   6435  N  NZ  . LYS B 1 439 ? -43.680 25.998  12.811  1.00 49.11  ? 418 LYS B NZ  1 
ATOM   6436  N  N   . SER B 1 440 ? -43.294 30.890  18.779  1.00 29.75  ? 419 SER B N   1 
ATOM   6437  C  CA  . SER B 1 440 ? -42.739 32.033  19.478  1.00 26.48  ? 419 SER B CA  1 
ATOM   6438  C  C   . SER B 1 440 ? -42.631 31.801  20.975  1.00 26.56  ? 419 SER B C   1 
ATOM   6439  O  O   . SER B 1 440 ? -42.033 32.637  21.669  1.00 28.73  ? 419 SER B O   1 
ATOM   6440  C  CB  . SER B 1 440 ? -43.605 33.256  19.254  1.00 27.27  ? 419 SER B CB  1 
ATOM   6441  O  OG  . SER B 1 440 ? -44.754 33.107  20.072  1.00 26.06  ? 419 SER B OG  1 
ATOM   6442  N  N   . GLY B 1 441 ? -43.207 30.718  21.494  1.00 26.77  ? 420 GLY B N   1 
ATOM   6443  C  CA  . GLY B 1 441 ? -43.349 30.566  22.949  1.00 20.17  ? 420 GLY B CA  1 
ATOM   6444  C  C   . GLY B 1 441 ? -44.547 31.268  23.567  1.00 25.87  ? 420 GLY B C   1 
ATOM   6445  O  O   . GLY B 1 441 ? -44.781 31.103  24.782  1.00 24.06  ? 420 GLY B O   1 
ATOM   6446  N  N   . VAL B 1 442 ? -45.321 32.005  22.753  1.00 20.41  ? 421 VAL B N   1 
ATOM   6447  C  CA  . VAL B 1 442 ? -46.490 32.815  23.109  1.00 21.06  ? 421 VAL B CA  1 
ATOM   6448  C  C   . VAL B 1 442 ? -46.048 34.115  23.762  1.00 23.36  ? 421 VAL B C   1 
ATOM   6449  O  O   . VAL B 1 442 ? -45.751 34.158  24.963  1.00 22.70  ? 421 VAL B O   1 
ATOM   6450  C  CB  . VAL B 1 442 ? -47.497 32.097  24.019  1.00 22.77  ? 421 VAL B CB  1 
ATOM   6451  C  CG1 . VAL B 1 442 ? -48.758 32.980  24.140  1.00 20.52  ? 421 VAL B CG1 1 
ATOM   6452  C  CG2 . VAL B 1 442 ? -47.869 30.734  23.443  1.00 21.81  ? 421 VAL B CG2 1 
ATOM   6453  N  N   . ARG B 1 443 ? -46.036 35.198  22.987  1.00 23.86  ? 422 ARG B N   1 
ATOM   6454  C  CA  . ARG B 1 443 ? -45.625 36.478  23.544  1.00 23.76  ? 422 ARG B CA  1 
ATOM   6455  C  C   . ARG B 1 443 ? -46.777 37.089  24.338  1.00 25.99  ? 422 ARG B C   1 
ATOM   6456  O  O   . ARG B 1 443 ? -47.947 36.955  23.974  1.00 25.13  ? 422 ARG B O   1 
ATOM   6457  C  CB  . ARG B 1 443 ? -45.138 37.408  22.423  1.00 24.10  ? 422 ARG B CB  1 
ATOM   6458  C  CG  . ARG B 1 443 ? -43.841 36.854  21.770  1.00 25.60  ? 422 ARG B CG  1 
ATOM   6459  C  CD  . ARG B 1 443 ? -43.446 37.621  20.513  1.00 30.99  ? 422 ARG B CD  1 
ATOM   6460  N  NE  . ARG B 1 443 ? -44.433 37.438  19.452  1.00 25.48  ? 422 ARG B NE  1 
ATOM   6461  C  CZ  . ARG B 1 443 ? -44.498 38.194  18.370  1.00 29.22  ? 422 ARG B CZ  1 
ATOM   6462  N  NH1 . ARG B 1 443 ? -43.623 39.173  18.160  1.00 25.74  ? 422 ARG B NH1 1 
ATOM   6463  N  NH2 . ARG B 1 443 ? -45.476 37.986  17.490  1.00 27.28  ? 422 ARG B NH2 1 
ATOM   6464  N  N   . VAL B 1 444 ? -46.435 37.750  25.449  1.00 23.35  ? 423 VAL B N   1 
ATOM   6465  C  CA  . VAL B 1 444 ? -47.420 38.353  26.339  1.00 23.92  ? 423 VAL B CA  1 
ATOM   6466  C  C   . VAL B 1 444 ? -46.856 39.673  26.838  1.00 25.95  ? 423 VAL B C   1 
ATOM   6467  O  O   . VAL B 1 444 ? -45.642 39.885  26.877  1.00 25.58  ? 423 VAL B O   1 
ATOM   6468  C  CB  . VAL B 1 444 ? -47.779 37.458  27.564  1.00 28.96  ? 423 VAL B CB  1 
ATOM   6469  C  CG1 . VAL B 1 444 ? -48.703 36.375  27.165  1.00 35.00  ? 423 VAL B CG1 1 
ATOM   6470  C  CG2 . VAL B 1 444 ? -46.484 36.860  28.191  1.00 25.41  ? 423 VAL B CG2 1 
ATOM   6471  N  N   . THR B 1 445 ? -47.754 40.554  27.252  1.00 26.19  ? 424 THR B N   1 
ATOM   6472  C  CA  . THR B 1 445 ? -47.349 41.713  28.042  1.00 25.91  ? 424 THR B CA  1 
ATOM   6473  C  C   . THR B 1 445 ? -48.425 41.965  29.082  1.00 30.50  ? 424 THR B C   1 
ATOM   6474  O  O   . THR B 1 445 ? -49.541 41.466  28.962  1.00 27.78  ? 424 THR B O   1 
ATOM   6475  C  CB  . THR B 1 445 ? -47.128 42.950  27.167  1.00 27.67  ? 424 THR B CB  1 
ATOM   6476  O  OG1 . THR B 1 445 ? -46.567 44.016  27.976  1.00 31.83  ? 424 THR B OG1 1 
ATOM   6477  C  CG2 . THR B 1 445 ? -48.435 43.377  26.488  1.00 24.44  ? 424 THR B CG2 1 
ATOM   6478  N  N   . VAL B 1 446 ? -48.085 42.696  30.136  1.00 24.88  ? 425 VAL B N   1 
ATOM   6479  C  CA  . VAL B 1 446 ? -49.085 43.047  31.149  1.00 25.21  ? 425 VAL B CA  1 
ATOM   6480  C  C   . VAL B 1 446 ? -49.282 44.550  31.076  1.00 30.42  ? 425 VAL B C   1 
ATOM   6481  O  O   . VAL B 1 446 ? -48.315 45.313  31.156  1.00 29.26  ? 425 VAL B O   1 
ATOM   6482  C  CB  . VAL B 1 446 ? -48.692 42.578  32.551  1.00 30.13  ? 425 VAL B CB  1 
ATOM   6483  C  CG1 . VAL B 1 446 ? -49.547 43.261  33.628  1.00 27.93  ? 425 VAL B CG1 1 
ATOM   6484  C  CG2 . VAL B 1 446 ? -48.852 41.040  32.656  1.00 31.26  ? 425 VAL B CG2 1 
ATOM   6485  N  N   . ALA B 1 447 ? -50.523 44.958  30.847  1.00 31.13  ? 426 ALA B N   1 
ATOM   6486  C  CA  . ALA B 1 447 ? -50.855 46.369  30.805  1.00 38.58  ? 426 ALA B CA  1 
ATOM   6487  C  C   . ALA B 1 447 ? -50.404 47.051  32.095  1.00 32.95  ? 426 ALA B C   1 
ATOM   6488  O  O   . ALA B 1 447 ? -50.628 46.548  33.206  1.00 31.69  ? 426 ALA B O   1 
ATOM   6489  C  CB  . ALA B 1 447 ? -52.365 46.534  30.579  1.00 33.86  ? 426 ALA B CB  1 
ATOM   6490  N  N   . SER B 1 448 ? -49.719 48.178  31.940  1.00 35.70  ? 427 SER B N   1 
ATOM   6491  C  CA  . SER B 1 448 ? -49.253 48.981  33.060  1.00 44.82  ? 427 SER B CA  1 
ATOM   6492  C  C   . SER B 1 448 ? -49.617 50.438  32.819  1.00 46.14  ? 427 SER B C   1 
ATOM   6493  O  O   . SER B 1 448 ? -49.535 50.925  31.688  1.00 45.58  ? 427 SER B O   1 
ATOM   6494  C  CB  . SER B 1 448 ? -47.744 48.870  33.254  1.00 43.52  ? 427 SER B CB  1 
ATOM   6495  O  OG  . SER B 1 448 ? -47.325 49.761  34.273  1.00 53.90  ? 427 SER B OG  1 
ATOM   6496  N  N   . SER B 1 449 ? -50.024 51.129  33.877  1.00 46.04  ? 428 SER B N   1 
ATOM   6497  C  CA  . SER B 1 449 ? -50.296 52.558  33.740  1.00 60.48  ? 428 SER B CA  1 
ATOM   6498  C  C   . SER B 1 449 ? -48.964 53.310  33.760  1.00 64.05  ? 428 SER B C   1 
ATOM   6499  O  O   . SER B 1 449 ? -48.747 54.237  32.970  1.00 65.52  ? 428 SER B O   1 
ATOM   6500  C  CB  . SER B 1 449 ? -51.240 53.064  34.844  1.00 51.35  ? 428 SER B CB  1 
ATOM   6501  O  OG  . SER B 1 449 ? -50.690 52.896  36.144  1.00 42.41  ? 428 SER B OG  1 
ATOM   6502  N  N   . ASN C 1 29  ? -38.108 -53.051 -10.749 1.00 55.23  ? 8   ASN C N   1 
ATOM   6503  C  CA  . ASN C 1 29  ? -38.633 -52.323 -9.592  1.00 60.33  ? 8   ASN C CA  1 
ATOM   6504  C  C   . ASN C 1 29  ? -38.280 -50.837 -9.665  1.00 53.82  ? 8   ASN C C   1 
ATOM   6505  O  O   . ASN C 1 29  ? -37.210 -50.435 -9.206  1.00 53.83  ? 8   ASN C O   1 
ATOM   6506  C  CB  . ASN C 1 29  ? -38.092 -52.915 -8.289  1.00 62.45  ? 8   ASN C CB  1 
ATOM   6507  C  CG  . ASN C 1 29  ? -38.525 -52.117 -7.073  1.00 72.41  ? 8   ASN C CG  1 
ATOM   6508  O  OD1 . ASN C 1 29  ? -39.713 -52.033 -6.783  1.00 77.47  ? 8   ASN C OD1 1 
ATOM   6509  N  ND2 . ASN C 1 29  ? -37.568 -51.516 -6.367  1.00 70.50  ? 8   ASN C ND2 1 
ATOM   6510  N  N   . PRO C 1 30  ? -39.185 -50.028 -10.220 1.00 44.49  ? 9   PRO C N   1 
ATOM   6511  C  CA  . PRO C 1 30  ? -38.834 -48.636 -10.567 1.00 41.71  ? 9   PRO C CA  1 
ATOM   6512  C  C   . PRO C 1 30  ? -38.428 -47.838 -9.340  1.00 44.22  ? 9   PRO C C   1 
ATOM   6513  O  O   . PRO C 1 30  ? -39.153 -47.777 -8.348  1.00 34.22  ? 9   PRO C O   1 
ATOM   6514  C  CB  . PRO C 1 30  ? -40.126 -48.082 -11.190 1.00 39.82  ? 9   PRO C CB  1 
ATOM   6515  C  CG  . PRO C 1 30  ? -40.947 -49.304 -11.545 1.00 43.56  ? 9   PRO C CG  1 
ATOM   6516  C  CD  . PRO C 1 30  ? -40.580 -50.357 -10.543 1.00 42.51  ? 9   PRO C CD  1 
ATOM   6517  N  N   . ARG C 1 31  ? -37.268 -47.207 -9.420  1.00 42.96  ? 10  ARG C N   1 
ATOM   6518  C  CA  . ARG C 1 31  ? -36.726 -46.476 -8.293  1.00 44.06  ? 10  ARG C CA  1 
ATOM   6519  C  C   . ARG C 1 31  ? -36.138 -45.164 -8.786  1.00 42.03  ? 10  ARG C C   1 
ATOM   6520  O  O   . ARG C 1 31  ? -35.668 -45.062 -9.921  1.00 46.19  ? 10  ARG C O   1 
ATOM   6521  C  CB  . ARG C 1 31  ? -35.670 -47.309 -7.547  1.00 44.67  ? 10  ARG C CB  1 
ATOM   6522  C  CG  . ARG C 1 31  ? -34.906 -46.550 -6.474  1.00 55.15  ? 10  ARG C CG  1 
ATOM   6523  C  CD  . ARG C 1 31  ? -33.985 -47.465 -5.678  1.00 61.61  ? 10  ARG C CD  1 
ATOM   6524  N  NE  . ARG C 1 31  ? -34.489 -47.722 -4.334  1.00 60.93  ? 10  ARG C NE  1 
ATOM   6525  C  CZ  . ARG C 1 31  ? -35.168 -48.805 -3.982  1.00 65.47  ? 10  ARG C CZ  1 
ATOM   6526  N  NH1 . ARG C 1 31  ? -35.454 -49.758 -4.857  1.00 68.75  ? 10  ARG C NH1 1 
ATOM   6527  N  NH2 . ARG C 1 31  ? -35.566 -48.938 -2.719  1.00 59.78  ? 10  ARG C NH2 1 
ATOM   6528  N  N   . VAL C 1 32  ? -36.205 -44.153 -7.931  1.00 34.71  ? 11  VAL C N   1 
ATOM   6529  C  CA  . VAL C 1 32  ? -35.504 -42.892 -8.127  1.00 36.49  ? 11  VAL C CA  1 
ATOM   6530  C  C   . VAL C 1 32  ? -34.453 -42.823 -7.027  1.00 43.26  ? 11  VAL C C   1 
ATOM   6531  O  O   . VAL C 1 32  ? -34.789 -42.928 -5.841  1.00 38.59  ? 11  VAL C O   1 
ATOM   6532  C  CB  . VAL C 1 32  ? -36.472 -41.698 -8.071  1.00 45.25  ? 11  VAL C CB  1 
ATOM   6533  C  CG1 . VAL C 1 32  ? -35.721 -40.389 -8.064  1.00 43.37  ? 11  VAL C CG1 1 
ATOM   6534  C  CG2 . VAL C 1 32  ? -37.452 -41.763 -9.247  1.00 33.76  ? 11  VAL C CG2 1 
ATOM   6535  N  N   . SER C 1 33  ? -33.186 -42.684 -7.413  1.00 37.29  ? 12  SER C N   1 
ATOM   6536  C  CA  . SER C 1 33  ? -32.101 -42.794 -6.443  1.00 48.67  ? 12  SER C CA  1 
ATOM   6537  C  C   . SER C 1 33  ? -32.011 -41.551 -5.558  1.00 48.82  ? 12  SER C C   1 
ATOM   6538  O  O   . SER C 1 33  ? -32.395 -40.447 -5.951  1.00 48.57  ? 12  SER C O   1 
ATOM   6539  C  CB  . SER C 1 33  ? -30.776 -43.006 -7.165  1.00 42.73  ? 12  SER C CB  1 
ATOM   6540  O  OG  . SER C 1 33  ? -30.477 -41.867 -7.965  1.00 59.41  ? 12  SER C OG  1 
ATOM   6541  N  N   . GLY C 1 34  ? -31.481 -41.740 -4.345  1.00 45.87  ? 13  GLY C N   1 
ATOM   6542  C  CA  . GLY C 1 34  ? -31.216 -40.630 -3.444  1.00 48.79  ? 13  GLY C CA  1 
ATOM   6543  C  C   . GLY C 1 34  ? -32.416 -40.252 -2.594  1.00 45.42  ? 13  GLY C C   1 
ATOM   6544  O  O   . GLY C 1 34  ? -33.494 -40.850 -2.664  1.00 50.61  ? 13  GLY C O   1 
ATOM   6545  N  N   . ASP C 1 35  ? -32.225 -39.227 -1.770  1.00 44.37  ? 14  ASP C N   1 
ATOM   6546  C  CA  . ASP C 1 35  ? -33.289 -38.732 -0.904  1.00 54.03  ? 14  ASP C CA  1 
ATOM   6547  C  C   . ASP C 1 35  ? -33.964 -37.541 -1.572  1.00 53.69  ? 14  ASP C C   1 
ATOM   6548  O  O   . ASP C 1 35  ? -33.323 -36.515 -1.816  1.00 46.22  ? 14  ASP C O   1 
ATOM   6549  C  CB  . ASP C 1 35  ? -32.779 -38.342 0.484   1.00 45.35  ? 14  ASP C CB  1 
ATOM   6550  C  CG  . ASP C 1 35  ? -33.929 -38.071 1.464   1.00 57.86  ? 14  ASP C CG  1 
ATOM   6551  O  OD1 . ASP C 1 35  ? -34.659 -37.076 1.264   1.00 47.07  ? 14  ASP C OD1 1 
ATOM   6552  O  OD2 . ASP C 1 35  ? -34.131 -38.875 2.407   1.00 51.74  ? 14  ASP C OD2 1 
ATOM   6553  N  N   . ARG C 1 36  ? -35.266 -37.671 -1.826  1.00 43.99  ? 15  ARG C N   1 
ATOM   6554  C  CA  . ARG C 1 36  ? -36.023 -36.695 -2.594  1.00 40.09  ? 15  ARG C CA  1 
ATOM   6555  C  C   . ARG C 1 36  ? -36.937 -35.850 -1.723  1.00 36.17  ? 15  ARG C C   1 
ATOM   6556  O  O   . ARG C 1 36  ? -37.879 -35.247 -2.246  1.00 38.79  ? 15  ARG C O   1 
ATOM   6557  C  CB  . ARG C 1 36  ? -36.830 -37.404 -3.682  1.00 34.03  ? 15  ARG C CB  1 
ATOM   6558  C  CG  . ARG C 1 36  ? -35.931 -38.068 -4.735  1.00 45.71  ? 15  ARG C CG  1 
ATOM   6559  C  CD  . ARG C 1 36  ? -34.834 -37.121 -5.191  1.00 44.15  ? 15  ARG C CD  1 
ATOM   6560  N  NE  . ARG C 1 36  ? -33.891 -37.784 -6.085  1.00 62.13  ? 15  ARG C NE  1 
ATOM   6561  C  CZ  . ARG C 1 36  ? -33.863 -37.637 -7.405  1.00 65.78  ? 15  ARG C CZ  1 
ATOM   6562  N  NH1 . ARG C 1 36  ? -34.725 -36.853 -8.035  1.00 58.14  ? 15  ARG C NH1 1 
ATOM   6563  N  NH2 . ARG C 1 36  ? -32.947 -38.297 -8.112  1.00 60.76  ? 15  ARG C NH2 1 
ATOM   6564  N  N   . THR C 1 37  ? -36.653 -35.761 -0.414  1.00 34.75  ? 16  THR C N   1 
ATOM   6565  C  CA  . THR C 1 37  ? -37.531 -35.020 0.488   1.00 38.06  ? 16  THR C CA  1 
ATOM   6566  C  C   . THR C 1 37  ? -37.698 -33.570 0.060   1.00 36.48  ? 16  THR C C   1 
ATOM   6567  O  O   . THR C 1 37  ? -38.806 -33.027 0.140   1.00 34.94  ? 16  THR C O   1 
ATOM   6568  C  CB  . THR C 1 37  ? -37.022 -35.072 1.931   1.00 35.35  ? 16  THR C CB  1 
ATOM   6569  O  OG1 . THR C 1 37  ? -36.809 -36.426 2.328   1.00 43.94  ? 16  THR C OG1 1 
ATOM   6570  C  CG2 . THR C 1 37  ? -38.053 -34.461 2.873   1.00 46.13  ? 16  THR C CG2 1 
ATOM   6571  N  N   . ILE C 1 38  ? -36.616 -32.913 -0.382  1.00 34.00  ? 17  ILE C N   1 
ATOM   6572  C  CA  . ILE C 1 38  ? -36.741 -31.489 -0.714  1.00 32.39  ? 17  ILE C CA  1 
ATOM   6573  C  C   . ILE C 1 38  ? -37.633 -31.280 -1.925  1.00 39.79  ? 17  ILE C C   1 
ATOM   6574  O  O   . ILE C 1 38  ? -38.220 -30.202 -2.085  1.00 36.35  ? 17  ILE C O   1 
ATOM   6575  C  CB  . ILE C 1 38  ? -35.376 -30.831 -0.977  1.00 39.81  ? 17  ILE C CB  1 
ATOM   6576  C  CG1 . ILE C 1 38  ? -34.746 -31.419 -2.247  1.00 46.95  ? 17  ILE C CG1 1 
ATOM   6577  C  CG2 . ILE C 1 38  ? -34.453 -30.990 0.258   1.00 50.57  ? 17  ILE C CG2 1 
ATOM   6578  C  CD1 . ILE C 1 38  ? -33.343 -30.906 -2.541  1.00 58.22  ? 17  ILE C CD1 1 
ATOM   6579  N  N   . GLN C 1 39  ? -37.760 -32.297 -2.774  1.00 34.39  ? 18  GLN C N   1 
ATOM   6580  C  CA  . GLN C 1 39  ? -38.646 -32.211 -3.925  1.00 36.38  ? 18  GLN C CA  1 
ATOM   6581  C  C   . GLN C 1 39  ? -40.117 -32.076 -3.523  1.00 34.83  ? 18  GLN C C   1 
ATOM   6582  O  O   . GLN C 1 39  ? -40.926 -31.652 -4.353  1.00 36.33  ? 18  GLN C O   1 
ATOM   6583  C  CB  . GLN C 1 39  ? -38.426 -33.431 -4.819  1.00 33.59  ? 18  GLN C CB  1 
ATOM   6584  C  CG  . GLN C 1 39  ? -38.491 -33.100 -6.269  1.00 44.54  ? 18  GLN C CG  1 
ATOM   6585  C  CD  . GLN C 1 39  ? -38.073 -34.255 -7.153  1.00 40.10  ? 18  GLN C CD  1 
ATOM   6586  O  OE1 . GLN C 1 39  ? -37.111 -34.955 -6.866  1.00 47.12  ? 18  GLN C OE1 1 
ATOM   6587  N  NE2 . GLN C 1 39  ? -38.794 -34.447 -8.241  1.00 43.73  ? 18  GLN C NE2 1 
ATOM   6588  N  N   . PHE C 1 40  ? -40.484 -32.381 -2.268  1.00 36.30  ? 19  PHE C N   1 
ATOM   6589  C  CA  . PHE C 1 40  ? -41.866 -32.165 -1.836  1.00 33.34  ? 19  PHE C CA  1 
ATOM   6590  C  C   . PHE C 1 40  ? -42.227 -30.685 -1.834  1.00 40.50  ? 19  PHE C C   1 
ATOM   6591  O  O   . PHE C 1 40  ? -43.298 -30.294 -2.320  1.00 38.42  ? 19  PHE C O   1 
ATOM   6592  C  CB  . PHE C 1 40  ? -42.110 -32.776 -0.453  1.00 42.31  ? 19  PHE C CB  1 
ATOM   6593  C  CG  . PHE C 1 40  ? -43.486 -32.465 0.121   1.00 58.49  ? 19  PHE C CG  1 
ATOM   6594  C  CD1 . PHE C 1 40  ? -44.583 -33.264 -0.188  1.00 49.82  ? 19  PHE C CD1 1 
ATOM   6595  C  CD2 . PHE C 1 40  ? -43.679 -31.364 0.963   1.00 52.62  ? 19  PHE C CD2 1 
ATOM   6596  C  CE1 . PHE C 1 40  ? -45.848 -32.975 0.335   1.00 46.71  ? 19  PHE C CE1 1 
ATOM   6597  C  CE2 . PHE C 1 40  ? -44.932 -31.067 1.486   1.00 56.42  ? 19  PHE C CE2 1 
ATOM   6598  C  CZ  . PHE C 1 40  ? -46.019 -31.878 1.178   1.00 45.62  ? 19  PHE C CZ  1 
ATOM   6599  N  N   . LEU C 1 41  ? -41.359 -29.839 -1.265  1.00 34.64  ? 20  LEU C N   1 
ATOM   6600  C  CA  . LEU C 1 41  ? -41.620 -28.407 -1.293  1.00 34.77  ? 20  LEU C CA  1 
ATOM   6601  C  C   . LEU C 1 41  ? -41.491 -27.836 -2.696  1.00 37.29  ? 20  LEU C C   1 
ATOM   6602  O  O   . LEU C 1 41  ? -42.237 -26.925 -3.069  1.00 42.01  ? 20  LEU C O   1 
ATOM   6603  C  CB  . LEU C 1 41  ? -40.680 -27.672 -0.323  1.00 47.48  ? 20  LEU C CB  1 
ATOM   6604  C  CG  . LEU C 1 41  ? -41.036 -27.847 1.154   1.00 44.21  ? 20  LEU C CG  1 
ATOM   6605  C  CD1 . LEU C 1 41  ? -40.081 -27.049 2.086   1.00 35.61  ? 20  LEU C CD1 1 
ATOM   6606  C  CD2 . LEU C 1 41  ? -42.503 -27.454 1.383   1.00 38.28  ? 20  LEU C CD2 1 
ATOM   6607  N  N   . THR C 1 42  ? -40.550 -28.340 -3.497  1.00 30.39  ? 21  THR C N   1 
ATOM   6608  C  CA  . THR C 1 42  ? -40.363 -27.713 -4.793  1.00 37.49  ? 21  THR C CA  1 
ATOM   6609  C  C   . THR C 1 42  ? -41.378 -28.204 -5.826  1.00 38.31  ? 21  THR C C   1 
ATOM   6610  O  O   . THR C 1 42  ? -41.692 -27.465 -6.763  1.00 35.07  ? 21  THR C O   1 
ATOM   6611  C  CB  . THR C 1 42  ? -38.939 -27.945 -5.290  1.00 37.73  ? 21  THR C CB  1 
ATOM   6612  O  OG1 . THR C 1 42  ? -38.712 -29.353 -5.447  1.00 42.63  ? 21  THR C OG1 1 
ATOM   6613  C  CG2 . THR C 1 42  ? -37.932 -27.380 -4.287  1.00 42.22  ? 21  THR C CG2 1 
ATOM   6614  N  N   . ASP C 1 43  ? -41.898 -29.426 -5.690  1.00 31.83  ? 22  ASP C N   1 
ATOM   6615  C  CA  . ASP C 1 43  ? -42.789 -29.972 -6.723  1.00 23.44  ? 22  ASP C CA  1 
ATOM   6616  C  C   . ASP C 1 43  ? -44.260 -29.982 -6.320  1.00 25.42  ? 22  ASP C C   1 
ATOM   6617  O  O   . ASP C 1 43  ? -45.131 -29.923 -7.205  1.00 24.58  ? 22  ASP C O   1 
ATOM   6618  C  CB  . ASP C 1 43  ? -42.405 -31.412 -7.095  1.00 27.29  ? 22  ASP C CB  1 
ATOM   6619  C  CG  . ASP C 1 43  ? -41.167 -31.481 -7.997  1.00 50.57  ? 22  ASP C CG  1 
ATOM   6620  O  OD1 . ASP C 1 43  ? -40.381 -30.503 -8.015  1.00 48.42  ? 22  ASP C OD1 1 
ATOM   6621  O  OD2 . ASP C 1 43  ? -40.989 -32.515 -8.692  1.00 44.62  ? 22  ASP C OD2 1 
ATOM   6622  N  N   . GLY C 1 44  ? -44.548 -30.080 -5.026  1.00 25.95  ? 23  GLY C N   1 
ATOM   6623  C  CA  . GLY C 1 44  ? -45.937 -30.050 -4.567  1.00 27.22  ? 23  GLY C CA  1 
ATOM   6624  C  C   . GLY C 1 44  ? -46.748 -31.162 -5.208  1.00 28.97  ? 23  GLY C C   1 
ATOM   6625  O  O   . GLY C 1 44  ? -46.378 -32.347 -5.158  1.00 25.56  ? 23  GLY C O   1 
ATOM   6626  N  N   . TYR C 1 45  ? -47.882 -30.781 -5.813  1.00 23.80  ? 24  TYR C N   1 
ATOM   6627  C  CA  . TYR C 1 45  ? -48.749 -31.771 -6.463  1.00 20.62  ? 24  TYR C CA  1 
ATOM   6628  C  C   . TYR C 1 45  ? -48.083 -32.450 -7.657  1.00 20.11  ? 24  TYR C C   1 
ATOM   6629  O  O   . TYR C 1 45  ? -48.574 -33.492 -8.105  1.00 23.67  ? 24  TYR C O   1 
ATOM   6630  C  CB  . TYR C 1 45  ? -50.048 -31.114 -6.935  1.00 22.41  ? 24  TYR C CB  1 
ATOM   6631  C  CG  . TYR C 1 45  ? -50.866 -30.572 -5.806  1.00 20.23  ? 24  TYR C CG  1 
ATOM   6632  C  CD1 . TYR C 1 45  ? -51.797 -31.386 -5.154  1.00 20.13  ? 24  TYR C CD1 1 
ATOM   6633  C  CD2 . TYR C 1 45  ? -50.684 -29.258 -5.363  1.00 20.91  ? 24  TYR C CD2 1 
ATOM   6634  C  CE1 . TYR C 1 45  ? -52.539 -30.896 -4.110  1.00 20.07  ? 24  TYR C CE1 1 
ATOM   6635  C  CE2 . TYR C 1 45  ? -51.415 -28.760 -4.317  1.00 22.34  ? 24  TYR C CE2 1 
ATOM   6636  C  CZ  . TYR C 1 45  ? -52.351 -29.584 -3.698  1.00 23.80  ? 24  TYR C CZ  1 
ATOM   6637  O  OH  . TYR C 1 45  ? -53.063 -29.074 -2.644  1.00 22.25  ? 24  TYR C OH  1 
ATOM   6638  N  N   . LEU C 1 46  ? -46.991 -31.884 -8.189  1.00 22.01  ? 25  LEU C N   1 
ATOM   6639  C  CA  . LEU C 1 46  ? -46.308 -32.490 -9.336  1.00 23.08  ? 25  LEU C CA  1 
ATOM   6640  C  C   . LEU C 1 46  ? -45.347 -33.591 -8.933  1.00 23.30  ? 25  LEU C C   1 
ATOM   6641  O  O   . LEU C 1 46  ? -44.770 -34.234 -9.821  1.00 25.66  ? 25  LEU C O   1 
ATOM   6642  C  CB  . LEU C 1 46  ? -45.506 -31.446 -10.143 1.00 20.93  ? 25  LEU C CB  1 
ATOM   6643  C  CG  . LEU C 1 46  ? -46.312 -30.226 -10.637 1.00 27.07  ? 25  LEU C CG  1 
ATOM   6644  C  CD1 . LEU C 1 46  ? -45.383 -29.250 -11.377 1.00 27.85  ? 25  LEU C CD1 1 
ATOM   6645  C  CD2 . LEU C 1 46  ? -47.502 -30.690 -11.554 1.00 25.98  ? 25  LEU C CD2 1 
ATOM   6646  N  N   . LEU C 1 47  ? -45.142 -33.808 -7.632  1.00 23.06  ? 26  LEU C N   1 
ATOM   6647  C  CA  . LEU C 1 47  ? -44.105 -34.744 -7.194  1.00 26.13  ? 26  LEU C CA  1 
ATOM   6648  C  C   . LEU C 1 47  ? -44.330 -36.158 -7.717  1.00 23.77  ? 26  LEU C C   1 
ATOM   6649  O  O   . LEU C 1 47  ? -43.371 -36.756 -8.231  1.00 24.23  ? 26  LEU C O   1 
ATOM   6650  C  CB  . LEU C 1 47  ? -44.008 -34.728 -5.665  1.00 22.74  ? 26  LEU C CB  1 
ATOM   6651  C  CG  . LEU C 1 47  ? -42.992 -35.736 -5.091  1.00 29.68  ? 26  LEU C CG  1 
ATOM   6652  C  CD1 . LEU C 1 47  ? -41.604 -35.405 -5.642  1.00 30.97  ? 26  LEU C CD1 1 
ATOM   6653  C  CD2 . LEU C 1 47  ? -42.994 -35.712 -3.556  1.00 33.92  ? 26  LEU C CD2 1 
ATOM   6654  N  N   . PRO C 1 48  ? -45.521 -36.767 -7.600  1.00 21.71  ? 27  PRO C N   1 
ATOM   6655  C  CA  . PRO C 1 48  ? -45.639 -38.155 -8.061  1.00 23.55  ? 27  PRO C CA  1 
ATOM   6656  C  C   . PRO C 1 48  ? -45.434 -38.307 -9.552  1.00 24.92  ? 27  PRO C C   1 
ATOM   6657  O  O   . PRO C 1 48  ? -44.735 -39.235 -9.969  1.00 26.10  ? 27  PRO C O   1 
ATOM   6658  C  CB  . PRO C 1 48  ? -47.055 -38.564 -7.611  1.00 24.94  ? 27  PRO C CB  1 
ATOM   6659  C  CG  . PRO C 1 48  ? -47.316 -37.683 -6.399  1.00 23.44  ? 27  PRO C CG  1 
ATOM   6660  C  CD  . PRO C 1 48  ? -46.716 -36.350 -6.831  1.00 26.59  ? 27  PRO C CD  1 
ATOM   6661  N  N   . SER C 1 49  ? -45.983 -37.412 -10.391 1.00 22.67  ? 28  SER C N   1 
ATOM   6662  C  CA  . SER C 1 49  ? -45.751 -37.625 -11.820 1.00 26.00  ? 28  SER C CA  1 
ATOM   6663  C  C   . SER C 1 49  ? -44.298 -37.324 -12.186 1.00 24.70  ? 28  SER C C   1 
ATOM   6664  O  O   . SER C 1 49  ? -43.749 -37.951 -13.103 1.00 27.31  ? 28  SER C O   1 
ATOM   6665  C  CB  . SER C 1 49  ? -46.753 -36.821 -12.658 1.00 22.78  ? 28  SER C CB  1 
ATOM   6666  O  OG  . SER C 1 49  ? -46.713 -35.443 -12.359 1.00 26.74  ? 28  SER C OG  1 
ATOM   6667  N  N   . ASN C 1 50  ? -43.631 -36.432 -11.450 1.00 26.65  ? 29  ASN C N   1 
ATOM   6668  C  CA  . ASN C 1 50  ? -42.211 -36.206 -11.729 1.00 25.38  ? 29  ASN C CA  1 
ATOM   6669  C  C   . ASN C 1 50  ? -41.385 -37.442 -11.383 1.00 25.85  ? 29  ASN C C   1 
ATOM   6670  O  O   . ASN C 1 50  ? -40.463 -37.821 -12.127 1.00 25.59  ? 29  ASN C O   1 
ATOM   6671  C  CB  . ASN C 1 50  ? -41.683 -34.986 -10.947 1.00 25.71  ? 29  ASN C CB  1 
ATOM   6672  C  CG  . ASN C 1 50  ? -41.591 -33.715 -11.802 1.00 39.42  ? 29  ASN C CG  1 
ATOM   6673  O  OD1 . ASN C 1 50  ? -41.234 -33.752 -12.976 1.00 40.48  ? 29  ASN C OD1 1 
ATOM   6674  N  ND2 . ASN C 1 50  ? -41.936 -32.592 -11.209 1.00 39.01  ? 29  ASN C ND2 1 
ATOM   6675  N  N   . LEU C 1 51  ? -41.680 -38.072 -10.243 1.00 24.18  ? 30  LEU C N   1 
ATOM   6676  C  CA  . LEU C 1 51  ? -40.931 -39.275 -9.860  1.00 25.09  ? 30  LEU C CA  1 
ATOM   6677  C  C   . LEU C 1 51  ? -41.173 -40.428 -10.831 1.00 26.18  ? 30  LEU C C   1 
ATOM   6678  O  O   . LEU C 1 51  ? -40.218 -41.100 -11.244 1.00 26.89  ? 30  LEU C O   1 
ATOM   6679  C  CB  . LEU C 1 51  ? -41.285 -39.683 -8.433  1.00 25.96  ? 30  LEU C CB  1 
ATOM   6680  C  CG  . LEU C 1 51  ? -40.786 -38.727 -7.348  1.00 32.59  ? 30  LEU C CG  1 
ATOM   6681  C  CD1 . LEU C 1 51  ? -41.332 -39.128 -6.005  1.00 31.60  ? 30  LEU C CD1 1 
ATOM   6682  C  CD2 . LEU C 1 51  ? -39.250 -38.627 -7.293  1.00 37.15  ? 30  LEU C CD2 1 
ATOM   6683  N  N   . ARG C 1 52  ? -42.432 -40.676 -11.224 1.00 22.44  ? 31  ARG C N   1 
ATOM   6684  C  CA  . ARG C 1 52  ? -42.676 -41.723 -12.211 1.00 27.74  ? 31  ARG C CA  1 
ATOM   6685  C  C   . ARG C 1 52  ? -41.882 -41.447 -13.488 1.00 31.58  ? 31  ARG C C   1 
ATOM   6686  O  O   . ARG C 1 52  ? -41.277 -42.360 -14.076 1.00 27.79  ? 31  ARG C O   1 
ATOM   6687  C  CB  . ARG C 1 52  ? -44.173 -41.840 -12.517 1.00 25.55  ? 31  ARG C CB  1 
ATOM   6688  C  CG  . ARG C 1 52  ? -44.993 -42.509 -11.376 1.00 23.43  ? 31  ARG C CG  1 
ATOM   6689  C  CD  . ARG C 1 52  ? -46.448 -42.765 -11.832 1.00 25.12  ? 31  ARG C CD  1 
ATOM   6690  N  NE  . ARG C 1 52  ? -47.196 -41.519 -11.971 1.00 29.57  ? 31  ARG C NE  1 
ATOM   6691  C  CZ  . ARG C 1 52  ? -47.895 -40.963 -10.989 1.00 36.07  ? 31  ARG C CZ  1 
ATOM   6692  N  NH1 . ARG C 1 52  ? -47.966 -41.523 -9.784  1.00 27.44  ? 31  ARG C NH1 1 
ATOM   6693  N  NH2 . ARG C 1 52  ? -48.538 -39.816 -11.216 1.00 27.99  ? 31  ARG C NH2 1 
ATOM   6694  N  N   . LYS C 1 53  ? -41.843 -40.184 -13.908 1.00 26.17  ? 32  LYS C N   1 
ATOM   6695  C  CA  . LYS C 1 53  ? -41.092 -39.839 -15.110 1.00 28.51  ? 32  LYS C CA  1 
ATOM   6696  C  C   . LYS C 1 53  ? -39.608 -40.126 -14.922 1.00 25.33  ? 32  LYS C C   1 
ATOM   6697  O  O   . LYS C 1 53  ? -38.976 -40.780 -15.767 1.00 30.69  ? 32  LYS C O   1 
ATOM   6698  C  CB  . LYS C 1 53  ? -41.314 -38.364 -15.472 1.00 25.77  ? 32  LYS C CB  1 
ATOM   6699  C  CG  . LYS C 1 53  ? -40.431 -37.894 -16.650 1.00 32.69  ? 32  LYS C CG  1 
ATOM   6700  C  CD  . LYS C 1 53  ? -40.661 -36.424 -16.973 1.00 32.19  ? 32  LYS C CD  1 
ATOM   6701  C  CE  . LYS C 1 53  ? -39.435 -35.800 -17.664 1.00 46.24  ? 32  LYS C CE  1 
ATOM   6702  N  NZ  . LYS C 1 53  ? -39.559 -34.304 -17.741 1.00 52.08  ? 32  LYS C NZ  1 
ATOM   6703  N  N   . THR C 1 54  ? -39.040 -39.638 -13.822 1.00 25.99  ? 33  THR C N   1 
ATOM   6704  C  CA  . THR C 1 54  ? -37.617 -39.833 -13.552 1.00 30.52  ? 33  THR C CA  1 
ATOM   6705  C  C   . THR C 1 54  ? -37.272 -41.311 -13.435 1.00 30.91  ? 33  THR C C   1 
ATOM   6706  O  O   . THR C 1 54  ? -36.184 -41.728 -13.838 1.00 31.02  ? 33  THR C O   1 
ATOM   6707  C  CB  . THR C 1 54  ? -37.228 -39.064 -12.288 1.00 28.73  ? 33  THR C CB  1 
ATOM   6708  O  OG1 . THR C 1 54  ? -37.393 -37.651 -12.526 1.00 34.54  ? 33  THR C OG1 1 
ATOM   6709  C  CG2 . THR C 1 54  ? -35.753 -39.336 -11.881 1.00 32.67  ? 33  THR C CG2 1 
ATOM   6710  N  N   . ALA C 1 55  ? -38.188 -42.121 -12.919 1.00 28.56  ? 34  ALA C N   1 
ATOM   6711  C  CA  . ALA C 1 55  ? -37.958 -43.555 -12.802 1.00 39.82  ? 34  ALA C CA  1 
ATOM   6712  C  C   . ALA C 1 55  ? -37.976 -44.282 -14.145 1.00 34.23  ? 34  ALA C C   1 
ATOM   6713  O  O   . ALA C 1 55  ? -37.654 -45.475 -14.182 1.00 35.86  ? 34  ALA C O   1 
ATOM   6714  C  CB  . ALA C 1 55  ? -39.001 -44.175 -11.872 1.00 32.70  ? 34  ALA C CB  1 
ATOM   6715  N  N   . GLY C 1 56  ? -38.354 -43.614 -15.234 1.00 34.32  ? 35  GLY C N   1 
ATOM   6716  C  CA  . GLY C 1 56  ? -38.425 -44.246 -16.542 1.00 35.65  ? 35  GLY C CA  1 
ATOM   6717  C  C   . GLY C 1 56  ? -39.742 -44.907 -16.869 1.00 35.34  ? 35  GLY C C   1 
ATOM   6718  O  O   . GLY C 1 56  ? -39.826 -45.633 -17.864 1.00 36.27  ? 35  GLY C O   1 
ATOM   6719  N  N   . LEU C 1 57  ? -40.770 -44.696 -16.062 1.00 28.19  ? 36  LEU C N   1 
ATOM   6720  C  CA  . LEU C 1 57  ? -42.081 -45.246 -16.358 1.00 27.43  ? 36  LEU C CA  1 
ATOM   6721  C  C   . LEU C 1 57  ? -42.748 -44.468 -17.495 1.00 32.82  ? 36  LEU C C   1 
ATOM   6722  O  O   . LEU C 1 57  ? -42.514 -43.272 -17.687 1.00 33.77  ? 36  LEU C O   1 
ATOM   6723  C  CB  . LEU C 1 57  ? -42.954 -45.218 -15.105 1.00 31.52  ? 36  LEU C CB  1 
ATOM   6724  C  CG  . LEU C 1 57  ? -42.468 -46.104 -13.949 1.00 33.89  ? 36  LEU C CG  1 
ATOM   6725  C  CD1 . LEU C 1 57  ? -43.388 -45.945 -12.738 1.00 32.63  ? 36  LEU C CD1 1 
ATOM   6726  C  CD2 . LEU C 1 57  ? -42.425 -47.576 -14.402 1.00 34.43  ? 36  LEU C CD2 1 
ATOM   6727  N  N   . GLU C 1 58  ? -43.562 -45.165 -18.271 1.00 32.52  ? 37  GLU C N   1 
ATOM   6728  C  CA  . GLU C 1 58  ? -44.313 -44.466 -19.303 1.00 33.65  ? 37  GLU C CA  1 
ATOM   6729  C  C   . GLU C 1 58  ? -45.468 -43.688 -18.678 1.00 30.53  ? 37  GLU C C   1 
ATOM   6730  O  O   . GLU C 1 58  ? -45.961 -44.046 -17.596 1.00 30.96  ? 37  GLU C O   1 
ATOM   6731  C  CB  . GLU C 1 58  ? -44.856 -45.445 -20.337 1.00 38.09  ? 37  GLU C CB  1 
ATOM   6732  C  CG  . GLU C 1 58  ? -43.762 -46.132 -21.148 1.00 63.19  ? 37  GLU C CG  1 
ATOM   6733  C  CD  . GLU C 1 58  ? -44.304 -47.188 -22.108 1.00 91.00  ? 37  GLU C CD  1 
ATOM   6734  O  OE1 . GLU C 1 58  ? -45.533 -47.442 -22.095 1.00 78.16  ? 37  GLU C OE1 1 
ATOM   6735  O  OE2 . GLU C 1 58  ? -43.494 -47.762 -22.873 1.00 95.70  ? 37  GLU C OE2 1 
ATOM   6736  N  N   . PRO C 1 59  ? -45.911 -42.612 -19.336 1.00 32.65  ? 38  PRO C N   1 
ATOM   6737  C  CA  . PRO C 1 59  ? -47.112 -41.917 -18.868 1.00 32.90  ? 38  PRO C CA  1 
ATOM   6738  C  C   . PRO C 1 59  ? -48.244 -42.906 -18.721 1.00 39.17  ? 38  PRO C C   1 
ATOM   6739  O  O   . PRO C 1 59  ? -48.369 -43.846 -19.509 1.00 37.43  ? 38  PRO C O   1 
ATOM   6740  C  CB  . PRO C 1 59  ? -47.402 -40.905 -19.982 1.00 33.23  ? 38  PRO C CB  1 
ATOM   6741  C  CG  . PRO C 1 59  ? -46.077 -40.660 -20.617 1.00 31.98  ? 38  PRO C CG  1 
ATOM   6742  C  CD  . PRO C 1 59  ? -45.352 -41.990 -20.554 1.00 39.38  ? 38  PRO C CD  1 
ATOM   6743  N  N   . GLU C 1 60  ? -49.045 -42.697 -17.684 1.00 32.42  ? 39  GLU C N   1 
ATOM   6744  C  CA  . GLU C 1 60  ? -50.206 -43.508 -17.320 1.00 36.56  ? 39  GLU C CA  1 
ATOM   6745  C  C   . GLU C 1 60  ? -49.849 -44.880 -16.761 1.00 27.58  ? 39  GLU C C   1 
ATOM   6746  O  O   . GLU C 1 60  ? -50.766 -45.672 -16.481 1.00 32.70  ? 39  GLU C O   1 
ATOM   6747  C  CB  . GLU C 1 60  ? -51.183 -43.667 -18.493 1.00 45.60  ? 39  GLU C CB  1 
ATOM   6748  C  CG  . GLU C 1 60  ? -51.548 -42.321 -19.164 1.00 47.17  ? 39  GLU C CG  1 
ATOM   6749  C  CD  . GLU C 1 60  ? -52.295 -41.323 -18.254 1.00 59.14  ? 39  GLU C CD  1 
ATOM   6750  O  OE1 . GLU C 1 60  ? -52.669 -41.617 -17.057 1.00 33.64  ? 39  GLU C OE1 1 
ATOM   6751  O  OE2 . GLU C 1 60  ? -52.517 -40.215 -18.785 1.00 50.16  ? 39  GLU C OE2 1 
ATOM   6752  N  N   . SER C 1 61  ? -48.568 -45.179 -16.546 1.00 29.79  ? 40  SER C N   1 
ATOM   6753  C  CA  . SER C 1 61  ? -48.205 -46.438 -15.894 1.00 34.51  ? 40  SER C CA  1 
ATOM   6754  C  C   . SER C 1 61  ? -48.872 -46.582 -14.528 1.00 32.53  ? 40  SER C C   1 
ATOM   6755  O  O   . SER C 1 61  ? -48.948 -45.626 -13.746 1.00 32.66  ? 40  SER C O   1 
ATOM   6756  C  CB  . SER C 1 61  ? -46.682 -46.546 -15.707 1.00 32.49  ? 40  SER C CB  1 
ATOM   6757  O  OG  . SER C 1 61  ? -46.372 -47.709 -14.935 1.00 33.27  ? 40  SER C OG  1 
ATOM   6758  N  N   . MET C 1 62  ? -49.328 -47.802 -14.219 1.00 31.92  ? 41  MET C N   1 
ATOM   6759  C  CA  . MET C 1 62  ? -49.826 -48.126 -12.889 1.00 31.42  ? 41  MET C CA  1 
ATOM   6760  C  C   . MET C 1 62  ? -48.769 -48.813 -12.019 1.00 36.53  ? 41  MET C C   1 
ATOM   6761  O  O   . MET C 1 62  ? -49.100 -49.322 -10.947 1.00 36.69  ? 41  MET C O   1 
ATOM   6762  C  CB  . MET C 1 62  ? -51.079 -49.004 -12.975 1.00 38.58  ? 41  MET C CB  1 
ATOM   6763  C  CG  . MET C 1 62  ? -52.179 -48.456 -13.871 1.00 39.14  ? 41  MET C CG  1 
ATOM   6764  S  SD  . MET C 1 62  ? -52.694 -46.741 -13.546 1.00 44.55  ? 41  MET C SD  1 
ATOM   6765  C  CE  . MET C 1 62  ? -53.778 -46.991 -12.154 1.00 39.42  ? 41  MET C CE  1 
ATOM   6766  N  N   . CYS C 1 63  ? -47.517 -48.842 -12.456 1.00 31.84  ? 42  CYS C N   1 
ATOM   6767  C  CA  . CYS C 1 63  ? -46.446 -49.413 -11.639 1.00 32.13  ? 42  CYS C CA  1 
ATOM   6768  C  C   . CYS C 1 63  ? -46.080 -48.492 -10.474 1.00 34.41  ? 42  CYS C C   1 
ATOM   6769  O  O   . CYS C 1 63  ? -46.086 -47.266 -10.611 1.00 36.72  ? 42  CYS C O   1 
ATOM   6770  C  CB  . CYS C 1 63  ? -45.191 -49.632 -12.465 1.00 32.43  ? 42  CYS C CB  1 
ATOM   6771  S  SG  . CYS C 1 63  ? -45.368 -50.832 -13.760 1.00 53.67  ? 42  CYS C SG  1 
ATOM   6772  N  N   . PRO C 1 64  ? -45.697 -49.059 -9.336  1.00 35.02  ? 43  PRO C N   1 
ATOM   6773  C  CA  . PRO C 1 64  ? -45.211 -48.232 -8.228  1.00 32.19  ? 43  PRO C CA  1 
ATOM   6774  C  C   . PRO C 1 64  ? -43.853 -47.629 -8.561  1.00 36.30  ? 43  PRO C C   1 
ATOM   6775  O  O   . PRO C 1 64  ? -43.118 -48.130 -9.414  1.00 31.43  ? 43  PRO C O   1 
ATOM   6776  C  CB  . PRO C 1 64  ? -45.102 -49.229 -7.067  1.00 32.89  ? 43  PRO C CB  1 
ATOM   6777  C  CG  . PRO C 1 64  ? -44.897 -50.545 -7.731  1.00 41.19  ? 43  PRO C CG  1 
ATOM   6778  C  CD  . PRO C 1 64  ? -45.722 -50.494 -8.998  1.00 34.31  ? 43  PRO C CD  1 
ATOM   6779  N  N   . VAL C 1 65  ? -43.521 -46.541 -7.867  1.00 26.08  ? 44  VAL C N   1 
ATOM   6780  C  CA  . VAL C 1 65  ? -42.186 -45.945 -7.923  1.00 27.76  ? 44  VAL C CA  1 
ATOM   6781  C  C   . VAL C 1 65  ? -41.692 -45.754 -6.492  1.00 36.90  ? 44  VAL C C   1 
ATOM   6782  O  O   . VAL C 1 65  ? -42.444 -45.303 -5.620  1.00 29.86  ? 44  VAL C O   1 
ATOM   6783  C  CB  . VAL C 1 65  ? -42.175 -44.606 -8.702  1.00 30.21  ? 44  VAL C CB  1 
ATOM   6784  C  CG1 . VAL C 1 65  ? -43.102 -43.589 -8.052  1.00 33.32  ? 44  VAL C CG1 1 
ATOM   6785  C  CG2 . VAL C 1 65  ? -40.780 -44.016 -8.767  1.00 30.51  ? 44  VAL C CG2 1 
ATOM   6786  N  N   . THR C 1 66  ? -40.440 -46.124 -6.241  1.00 36.43  ? 45  THR C N   1 
ATOM   6787  C  CA  . THR C 1 66  ? -39.865 -46.093 -4.904  1.00 31.38  ? 45  THR C CA  1 
ATOM   6788  C  C   . THR C 1 66  ? -38.729 -45.084 -4.873  1.00 34.85  ? 45  THR C C   1 
ATOM   6789  O  O   . THR C 1 66  ? -37.932 -44.999 -5.815  1.00 37.06  ? 45  THR C O   1 
ATOM   6790  C  CB  . THR C 1 66  ? -39.368 -47.486 -4.493  1.00 30.40  ? 45  THR C CB  1 
ATOM   6791  O  OG1 . THR C 1 66  ? -40.478 -48.389 -4.460  1.00 38.44  ? 45  THR C OG1 1 
ATOM   6792  C  CG2 . THR C 1 66  ? -38.709 -47.465 -3.102  1.00 35.49  ? 45  THR C CG2 1 
ATOM   6793  N  N   . THR C 1 67  ? -38.671 -44.296 -3.809  1.00 31.50  ? 46  THR C N   1 
ATOM   6794  C  CA  . THR C 1 67  ? -37.532 -43.408 -3.591  1.00 30.34  ? 46  THR C CA  1 
ATOM   6795  C  C   . THR C 1 67  ? -37.318 -43.309 -2.092  1.00 34.68  ? 46  THR C C   1 
ATOM   6796  O  O   . THR C 1 67  ? -37.915 -44.064 -1.329  1.00 36.31  ? 46  THR C O   1 
ATOM   6797  C  CB  . THR C 1 67  ? -37.751 -42.028 -4.225  1.00 42.79  ? 46  THR C CB  1 
ATOM   6798  O  OG1 . THR C 1 67  ? -36.526 -41.274 -4.143  1.00 37.55  ? 46  THR C OG1 1 
ATOM   6799  C  CG2 . THR C 1 67  ? -38.876 -41.262 -3.504  1.00 38.39  ? 46  THR C CG2 1 
ATOM   6800  N  N   . LYS C 1 68  ? -36.472 -42.380 -1.655  1.00 35.01  ? 47  LYS C N   1 
ATOM   6801  C  CA  . LYS C 1 68  ? -36.302 -42.130 -0.231  1.00 34.77  ? 47  LYS C CA  1 
ATOM   6802  C  C   . LYS C 1 68  ? -36.933 -40.793 0.141   1.00 32.05  ? 47  LYS C C   1 
ATOM   6803  O  O   . LYS C 1 68  ? -36.685 -39.774 -0.519  1.00 36.40  ? 47  LYS C O   1 
ATOM   6804  C  CB  . LYS C 1 68  ? -34.825 -42.171 0.166   1.00 37.79  ? 47  LYS C CB  1 
ATOM   6805  C  CG  . LYS C 1 68  ? -34.201 -43.537 -0.118  1.00 47.58  ? 47  LYS C CG  1 
ATOM   6806  C  CD  . LYS C 1 68  ? -33.109 -43.873 0.861   1.00 62.26  ? 47  LYS C CD  1 
ATOM   6807  C  CE  . LYS C 1 68  ? -33.692 -44.465 2.135   1.00 64.48  ? 47  LYS C CE  1 
ATOM   6808  N  NZ  . LYS C 1 68  ? -32.629 -44.943 3.072   1.00 66.81  ? 47  LYS C NZ  1 
ATOM   6809  N  N   . LEU C 1 69  ? -37.754 -40.809 1.190   1.00 35.85  ? 48  LEU C N   1 
ATOM   6810  C  CA  . LEU C 1 69  ? -38.367 -39.608 1.744   1.00 38.35  ? 48  LEU C CA  1 
ATOM   6811  C  C   . LEU C 1 69  ? -38.203 -39.665 3.248   1.00 36.94  ? 48  LEU C C   1 
ATOM   6812  O  O   . LEU C 1 69  ? -38.474 -40.706 3.860   1.00 38.44  ? 48  LEU C O   1 
ATOM   6813  C  CB  . LEU C 1 69  ? -39.872 -39.475 1.374   1.00 32.93  ? 48  LEU C CB  1 
ATOM   6814  C  CG  . LEU C 1 69  ? -40.273 -39.285 -0.099  1.00 44.23  ? 48  LEU C CG  1 
ATOM   6815  C  CD1 . LEU C 1 69  ? -41.787 -39.212 -0.261  1.00 43.74  ? 48  LEU C CD1 1 
ATOM   6816  C  CD2 . LEU C 1 69  ? -39.632 -38.052 -0.736  1.00 38.41  ? 48  LEU C CD2 1 
ATOM   6817  N  N   . LEU C 1 70  ? -37.750 -38.559 3.839   1.00 40.97  ? 49  LEU C N   1 
ATOM   6818  C  CA  . LEU C 1 70  ? -37.562 -38.466 5.290   1.00 40.34  ? 49  LEU C CA  1 
ATOM   6819  C  C   . LEU C 1 70  ? -36.627 -39.563 5.804   1.00 37.21  ? 49  LEU C C   1 
ATOM   6820  O  O   . LEU C 1 70  ? -36.822 -40.113 6.890   1.00 53.12  ? 49  LEU C O   1 
ATOM   6821  C  CB  . LEU C 1 70  ? -38.910 -38.511 6.015   1.00 48.34  ? 49  LEU C CB  1 
ATOM   6822  C  CG  . LEU C 1 70  ? -39.939 -37.482 5.512   1.00 55.12  ? 49  LEU C CG  1 
ATOM   6823  C  CD1 . LEU C 1 70  ? -41.308 -37.675 6.128   1.00 53.19  ? 49  LEU C CD1 1 
ATOM   6824  C  CD2 . LEU C 1 70  ? -39.452 -36.091 5.791   1.00 53.09  ? 49  LEU C CD2 1 
ATOM   6825  N  N   . GLY C 1 71  ? -35.612 -39.902 5.004   1.00 40.99  ? 50  GLY C N   1 
ATOM   6826  C  CA  . GLY C 1 71  ? -34.618 -40.895 5.368   1.00 39.68  ? 50  GLY C CA  1 
ATOM   6827  C  C   . GLY C 1 71  ? -35.008 -42.351 5.201   1.00 53.56  ? 50  GLY C C   1 
ATOM   6828  O  O   . GLY C 1 71  ? -34.161 -43.223 5.428   1.00 51.89  ? 50  GLY C O   1 
ATOM   6829  N  N   . GLN C 1 72  ? -36.244 -42.663 4.808   1.00 47.87  ? 51  GLN C N   1 
ATOM   6830  C  CA  . GLN C 1 72  ? -36.664 -44.053 4.654   1.00 38.37  ? 51  GLN C CA  1 
ATOM   6831  C  C   . GLN C 1 72  ? -37.293 -44.274 3.285   1.00 39.66  ? 51  GLN C C   1 
ATOM   6832  O  O   . GLN C 1 72  ? -37.663 -43.327 2.587   1.00 32.20  ? 51  GLN C O   1 
ATOM   6833  C  CB  . GLN C 1 72  ? -37.674 -44.473 5.727   1.00 51.20  ? 51  GLN C CB  1 
ATOM   6834  C  CG  . GLN C 1 72  ? -37.206 -44.302 7.155   1.00 65.63  ? 51  GLN C CG  1 
ATOM   6835  C  CD  . GLN C 1 72  ? -38.238 -44.794 8.151   1.00 76.33  ? 51  GLN C CD  1 
ATOM   6836  O  OE1 . GLN C 1 72  ? -39.172 -44.069 8.505   1.00 73.43  ? 51  GLN C OE1 1 
ATOM   6837  N  NE2 . GLN C 1 72  ? -38.083 -46.037 8.600   1.00 75.33  ? 51  GLN C NE2 1 
ATOM   6838  N  N   . ASP C 1 73  ? -37.420 -45.544 2.908   1.00 34.89  ? 52  ASP C N   1 
ATOM   6839  C  CA  . ASP C 1 73  ? -38.021 -45.865 1.621   1.00 38.84  ? 52  ASP C CA  1 
ATOM   6840  C  C   . ASP C 1 73  ? -39.483 -45.441 1.600   1.00 34.66  ? 52  ASP C C   1 
ATOM   6841  O  O   . ASP C 1 73  ? -40.187 -45.489 2.608   1.00 32.93  ? 52  ASP C O   1 
ATOM   6842  C  CB  . ASP C 1 73  ? -37.917 -47.356 1.325   1.00 34.42  ? 52  ASP C CB  1 
ATOM   6843  C  CG  . ASP C 1 73  ? -36.636 -47.708 0.572   1.00 54.57  ? 52  ASP C CG  1 
ATOM   6844  O  OD1 . ASP C 1 73  ? -35.815 -46.796 0.358   1.00 51.51  ? 52  ASP C OD1 1 
ATOM   6845  O  OD2 . ASP C 1 73  ? -36.464 -48.881 0.170   1.00 60.71  ? 52  ASP C OD2 1 
ATOM   6846  N  N   . ALA C 1 74  ? -39.932 -44.994 0.440   1.00 32.60  ? 53  ALA C N   1 
ATOM   6847  C  CA  . ALA C 1 74  ? -41.341 -44.679 0.262   1.00 28.51  ? 53  ALA C CA  1 
ATOM   6848  C  C   . ALA C 1 74  ? -41.735 -45.128 -1.133  1.00 35.21  ? 53  ALA C C   1 
ATOM   6849  O  O   . ALA C 1 74  ? -41.060 -44.799 -2.113  1.00 33.10  ? 53  ALA C O   1 
ATOM   6850  C  CB  . ALA C 1 74  ? -41.619 -43.184 0.440   1.00 27.08  ? 53  ALA C CB  1 
ATOM   6851  N  N   . THR C 1 75  ? -42.804 -45.892 -1.220  1.00 23.43  ? 54  THR C N   1 
ATOM   6852  C  CA  . THR C 1 75  ? -43.284 -46.353 -2.505  1.00 23.73  ? 54  THR C CA  1 
ATOM   6853  C  C   . THR C 1 75  ? -44.595 -45.642 -2.796  1.00 30.56  ? 54  THR C C   1 
ATOM   6854  O  O   . THR C 1 75  ? -45.488 -45.629 -1.945  1.00 30.68  ? 54  THR C O   1 
ATOM   6855  C  CB  . THR C 1 75  ? -43.460 -47.865 -2.495  1.00 31.96  ? 54  THR C CB  1 
ATOM   6856  O  OG1 . THR C 1 75  ? -42.190 -48.477 -2.211  1.00 32.89  ? 54  THR C OG1 1 
ATOM   6857  C  CG2 . THR C 1 75  ? -43.925 -48.328 -3.861  1.00 28.18  ? 54  THR C CG2 1 
ATOM   6858  N  N   . ILE C 1 76  ? -44.701 -45.047 -3.983  1.00 28.65  ? 55  ILE C N   1 
ATOM   6859  C  CA  . ILE C 1 76  ? -45.864 -44.244 -4.368  1.00 24.18  ? 55  ILE C CA  1 
ATOM   6860  C  C   . ILE C 1 76  ? -46.722 -45.069 -5.308  1.00 23.62  ? 55  ILE C C   1 
ATOM   6861  O  O   . ILE C 1 76  ? -46.228 -45.560 -6.334  1.00 25.66  ? 55  ILE C O   1 
ATOM   6862  C  CB  . ILE C 1 76  ? -45.439 -42.923 -5.033  1.00 23.92  ? 55  ILE C CB  1 
ATOM   6863  C  CG1 . ILE C 1 76  ? -44.702 -42.039 -4.026  1.00 29.65  ? 55  ILE C CG1 1 
ATOM   6864  C  CG2 . ILE C 1 76  ? -46.688 -42.162 -5.552  1.00 26.57  ? 55  ILE C CG2 1 
ATOM   6865  C  CD1 . ILE C 1 76  ? -44.189 -40.769 -4.656  1.00 37.03  ? 55  ILE C CD1 1 
ATOM   6866  N  N   . VAL C 1 77  ? -48.007 -45.228 -4.966  1.00 23.01  ? 56  VAL C N   1 
ATOM   6867  C  CA  . VAL C 1 77  ? -48.904 -46.046 -5.758  1.00 26.06  ? 56  VAL C CA  1 
ATOM   6868  C  C   . VAL C 1 77  ? -50.137 -45.214 -6.106  1.00 29.11  ? 56  VAL C C   1 
ATOM   6869  O  O   . VAL C 1 77  ? -50.417 -44.192 -5.486  1.00 23.96  ? 56  VAL C O   1 
ATOM   6870  C  CB  . VAL C 1 77  ? -49.300 -47.335 -5.019  1.00 29.81  ? 56  VAL C CB  1 
ATOM   6871  C  CG1 . VAL C 1 77  ? -48.014 -48.114 -4.611  1.00 29.52  ? 56  VAL C CG1 1 
ATOM   6872  C  CG2 . VAL C 1 77  ? -50.096 -46.999 -3.783  1.00 25.13  ? 56  VAL C CG2 1 
ATOM   6873  N  N   . ARG C 1 78  ? -50.885 -45.670 -7.097  1.00 24.42  ? 57  ARG C N   1 
ATOM   6874  C  CA  . ARG C 1 78  ? -52.112 -44.955 -7.458  1.00 29.44  ? 57  ARG C CA  1 
ATOM   6875  C  C   . ARG C 1 78  ? -53.031 -45.917 -8.197  1.00 33.22  ? 57  ARG C C   1 
ATOM   6876  O  O   . ARG C 1 78  ? -52.634 -47.027 -8.546  1.00 30.59  ? 57  ARG C O   1 
ATOM   6877  C  CB  . ARG C 1 78  ? -51.820 -43.708 -8.302  1.00 29.53  ? 57  ARG C CB  1 
ATOM   6878  C  CG  . ARG C 1 78  ? -50.996 -43.980 -9.535  1.00 28.84  ? 57  ARG C CG  1 
ATOM   6879  C  CD  . ARG C 1 78  ? -51.754 -43.818 -10.822 1.00 42.88  ? 57  ARG C CD  1 
ATOM   6880  N  NE  . ARG C 1 78  ? -50.861 -43.786 -11.983 1.00 37.86  ? 57  ARG C NE  1 
ATOM   6881  C  CZ  . ARG C 1 78  ? -50.797 -42.790 -12.856 1.00 33.43  ? 57  ARG C CZ  1 
ATOM   6882  N  NH1 . ARG C 1 78  ? -51.588 -41.734 -12.760 1.00 27.41  ? 57  ARG C NH1 1 
ATOM   6883  N  NH2 . ARG C 1 78  ? -49.932 -42.866 -13.863 1.00 29.11  ? 57  ARG C NH2 1 
ATOM   6884  N  N   . GLY C 1 79  ? -54.275 -45.481 -8.421  1.00 24.85  ? 58  GLY C N   1 
ATOM   6885  C  CA  . GLY C 1 79  ? -55.281 -46.332 -9.039  1.00 25.68  ? 58  GLY C CA  1 
ATOM   6886  C  C   . GLY C 1 79  ? -55.946 -47.322 -8.081  1.00 33.41  ? 58  GLY C C   1 
ATOM   6887  O  O   . GLY C 1 79  ? -55.653 -47.392 -6.891  1.00 23.82  ? 58  GLY C O   1 
ATOM   6888  N  N   . SER C 1 80  ? -56.865 -48.123 -8.640  1.00 28.21  ? 59  SER C N   1 
ATOM   6889  C  CA  . SER C 1 80  ? -57.671 -49.026 -7.815  1.00 26.28  ? 59  SER C CA  1 
ATOM   6890  C  C   . SER C 1 80  ? -56.805 -50.004 -7.027  1.00 27.40  ? 59  SER C C   1 
ATOM   6891  O  O   . SER C 1 80  ? -57.068 -50.260 -5.849  1.00 27.44  ? 59  SER C O   1 
ATOM   6892  C  CB  . SER C 1 80  ? -58.675 -49.781 -8.696  1.00 31.69  ? 59  SER C CB  1 
ATOM   6893  O  OG  . SER C 1 80  ? -59.690 -48.879 -9.131  1.00 36.03  ? 59  SER C OG  1 
ATOM   6894  N  N   . ALA C 1 81  ? -55.776 -50.559 -7.653  1.00 26.44  ? 60  ALA C N   1 
ATOM   6895  C  CA  . ALA C 1 81  ? -54.916 -51.510 -6.949  1.00 34.64  ? 60  ALA C CA  1 
ATOM   6896  C  C   . ALA C 1 81  ? -54.131 -50.830 -5.825  1.00 30.18  ? 60  ALA C C   1 
ATOM   6897  O  O   . ALA C 1 81  ? -53.926 -51.422 -4.751  1.00 28.49  ? 60  ALA C O   1 
ATOM   6898  C  CB  . ALA C 1 81  ? -53.969 -52.196 -7.944  1.00 32.62  ? 60  ALA C CB  1 
ATOM   6899  N  N   . GLY C 1 82  ? -53.697 -49.582 -6.040  1.00 27.89  ? 61  GLY C N   1 
ATOM   6900  C  CA  . GLY C 1 82  ? -53.012 -48.863 -4.972  1.00 23.54  ? 61  GLY C CA  1 
ATOM   6901  C  C   . GLY C 1 82  ? -53.936 -48.524 -3.820  1.00 24.92  ? 61  GLY C C   1 
ATOM   6902  O  O   . GLY C 1 82  ? -53.541 -48.581 -2.648  1.00 26.73  ? 61  GLY C O   1 
ATOM   6903  N  N   . ILE C 1 83  ? -55.194 -48.201 -4.133  1.00 22.43  ? 62  ILE C N   1 
ATOM   6904  C  CA  . ILE C 1 83  ? -56.199 -47.990 -3.101  1.00 25.06  ? 62  ILE C CA  1 
ATOM   6905  C  C   . ILE C 1 83  ? -56.363 -49.257 -2.266  1.00 27.78  ? 62  ILE C C   1 
ATOM   6906  O  O   . ILE C 1 83  ? -56.427 -49.203 -1.031  1.00 24.74  ? 62  ILE C O   1 
ATOM   6907  C  CB  . ILE C 1 83  ? -57.537 -47.562 -3.746  1.00 22.18  ? 62  ILE C CB  1 
ATOM   6908  C  CG1 . ILE C 1 83  ? -57.417 -46.168 -4.384  1.00 24.72  ? 62  ILE C CG1 1 
ATOM   6909  C  CG2 . ILE C 1 83  ? -58.682 -47.563 -2.726  1.00 23.88  ? 62  ILE C CG2 1 
ATOM   6910  C  CD1 . ILE C 1 83  ? -58.598 -45.833 -5.362  1.00 21.92  ? 62  ILE C CD1 1 
ATOM   6911  N  N   . ASP C 1 84  ? -56.434 -50.422 -2.917  1.00 25.50  ? 63  ASP C N   1 
ATOM   6912  C  CA  . ASP C 1 84  ? -56.630 -51.655 -2.146  1.00 26.31  ? 63  ASP C CA  1 
ATOM   6913  C  C   . ASP C 1 84  ? -55.454 -51.920 -1.204  1.00 29.89  ? 63  ASP C C   1 
ATOM   6914  O  O   . ASP C 1 84  ? -55.642 -52.354 -0.061  1.00 32.26  ? 63  ASP C O   1 
ATOM   6915  C  CB  . ASP C 1 84  ? -56.834 -52.855 -3.078  1.00 29.56  ? 63  ASP C CB  1 
ATOM   6916  C  CG  . ASP C 1 84  ? -58.181 -52.831 -3.779  1.00 34.38  ? 63  ASP C CG  1 
ATOM   6917  O  OD1 . ASP C 1 84  ? -59.096 -52.139 -3.285  1.00 34.15  ? 63  ASP C OD1 1 
ATOM   6918  O  OD2 . ASP C 1 84  ? -58.313 -53.488 -4.831  1.00 37.48  ? 63  ASP C OD2 1 
ATOM   6919  N  N   . LEU C 1 85  ? -54.235 -51.677 -1.670  1.00 26.91  ? 64  LEU C N   1 
ATOM   6920  C  CA  . LEU C 1 85  ? -53.067 -51.827 -0.808  1.00 25.59  ? 64  LEU C CA  1 
ATOM   6921  C  C   . LEU C 1 85  ? -53.102 -50.830 0.340   1.00 32.57  ? 64  LEU C C   1 
ATOM   6922  O  O   . LEU C 1 85  ? -52.951 -51.200 1.511   1.00 27.77  ? 64  LEU C O   1 
ATOM   6923  C  CB  . LEU C 1 85  ? -51.801 -51.624 -1.639  1.00 28.87  ? 64  LEU C CB  1 
ATOM   6924  C  CG  . LEU C 1 85  ? -50.506 -51.584 -0.816  1.00 29.64  ? 64  LEU C CG  1 
ATOM   6925  C  CD1 . LEU C 1 85  ? -50.256 -52.978 -0.240  1.00 31.13  ? 64  LEU C CD1 1 
ATOM   6926  C  CD2 . LEU C 1 85  ? -49.367 -51.137 -1.722  1.00 30.84  ? 64  LEU C CD2 1 
ATOM   6927  N  N   . PHE C 1 86  ? -53.301 -49.548 0.011   1.00 26.79  ? 65  PHE C N   1 
ATOM   6928  C  CA  . PHE C 1 86  ? -53.222 -48.483 0.997   1.00 21.77  ? 65  PHE C CA  1 
ATOM   6929  C  C   . PHE C 1 86  ? -54.196 -48.702 2.153   1.00 27.43  ? 65  PHE C C   1 
ATOM   6930  O  O   . PHE C 1 86  ? -53.880 -48.385 3.300   1.00 27.73  ? 65  PHE C O   1 
ATOM   6931  C  CB  . PHE C 1 86  ? -53.498 -47.137 0.307   1.00 21.74  ? 65  PHE C CB  1 
ATOM   6932  C  CG  . PHE C 1 86  ? -53.139 -45.935 1.132   1.00 25.32  ? 65  PHE C CG  1 
ATOM   6933  C  CD1 . PHE C 1 86  ? -51.791 -45.586 1.328   1.00 26.74  ? 65  PHE C CD1 1 
ATOM   6934  C  CD2 . PHE C 1 86  ? -54.127 -45.140 1.691   1.00 22.79  ? 65  PHE C CD2 1 
ATOM   6935  C  CE1 . PHE C 1 86  ? -51.450 -44.485 2.073   1.00 26.37  ? 65  PHE C CE1 1 
ATOM   6936  C  CE2 . PHE C 1 86  ? -53.806 -44.008 2.418   1.00 24.51  ? 65  PHE C CE2 1 
ATOM   6937  C  CZ  . PHE C 1 86  ? -52.454 -43.685 2.640   1.00 23.09  ? 65  PHE C CZ  1 
ATOM   6938  N  N   . TYR C 1 87  ? -55.392 -49.228 1.870   1.00 26.95  ? 66  TYR C N   1 
ATOM   6939  C  CA  . TYR C 1 87  ? -56.437 -49.365 2.872   1.00 30.39  ? 66  TYR C CA  1 
ATOM   6940  C  C   . TYR C 1 87  ? -56.525 -50.788 3.408   1.00 30.20  ? 66  TYR C C   1 
ATOM   6941  O  O   . TYR C 1 87  ? -57.503 -51.135 4.073   1.00 27.40  ? 66  TYR C O   1 
ATOM   6942  C  CB  . TYR C 1 87  ? -57.797 -48.910 2.296   1.00 29.40  ? 66  TYR C CB  1 
ATOM   6943  C  CG  . TYR C 1 87  ? -57.830 -47.397 2.147   1.00 26.46  ? 66  TYR C CG  1 
ATOM   6944  C  CD1 . TYR C 1 87  ? -58.017 -46.591 3.253   1.00 27.30  ? 66  TYR C CD1 1 
ATOM   6945  C  CD2 . TYR C 1 87  ? -57.599 -46.794 0.907   1.00 23.78  ? 66  TYR C CD2 1 
ATOM   6946  C  CE1 . TYR C 1 87  ? -58.007 -45.194 3.155   1.00 25.75  ? 66  TYR C CE1 1 
ATOM   6947  C  CE2 . TYR C 1 87  ? -57.564 -45.389 0.777   1.00 26.67  ? 66  TYR C CE2 1 
ATOM   6948  C  CZ  . TYR C 1 87  ? -57.791 -44.614 1.911   1.00 26.75  ? 66  TYR C CZ  1 
ATOM   6949  O  OH  . TYR C 1 87  ? -57.776 -43.263 1.843   1.00 25.06  ? 66  TYR C OH  1 
ATOM   6950  N  N   . ASP C 1 88  ? -55.525 -51.620 3.131   1.00 28.91  ? 67  ASP C N   1 
ATOM   6951  C  CA  . ASP C 1 88  ? -55.489 -52.949 3.737   1.00 32.28  ? 67  ASP C CA  1 
ATOM   6952  C  C   . ASP C 1 88  ? -54.863 -52.821 5.129   1.00 25.62  ? 67  ASP C C   1 
ATOM   6953  O  O   . ASP C 1 88  ? -53.641 -52.748 5.277   1.00 28.94  ? 67  ASP C O   1 
ATOM   6954  C  CB  . ASP C 1 88  ? -54.734 -53.914 2.832   1.00 32.71  ? 67  ASP C CB  1 
ATOM   6955  C  CG  . ASP C 1 88  ? -54.724 -55.333 3.371   1.00 34.74  ? 67  ASP C CG  1 
ATOM   6956  O  OD1 . ASP C 1 88  ? -55.172 -55.545 4.518   1.00 38.06  ? 67  ASP C OD1 1 
ATOM   6957  O  OD2 . ASP C 1 88  ? -54.254 -56.229 2.640   1.00 36.62  ? 67  ASP C OD2 1 
ATOM   6958  N  N   . GLU C 1 89  ? -55.694 -52.797 6.164   1.00 28.60  ? 68  GLU C N   1 
ATOM   6959  C  CA  . GLU C 1 89  ? -55.135 -52.593 7.497   1.00 32.60  ? 68  GLU C CA  1 
ATOM   6960  C  C   . GLU C 1 89  ? -54.438 -53.839 8.058   1.00 35.16  ? 68  GLU C C   1 
ATOM   6961  O  O   . GLU C 1 89  ? -53.871 -53.750 9.151   1.00 38.14  ? 68  GLU C O   1 
ATOM   6962  C  CB  . GLU C 1 89  ? -56.225 -52.105 8.463   1.00 32.73  ? 68  GLU C CB  1 
ATOM   6963  C  CG  . GLU C 1 89  ? -56.697 -50.690 8.135   1.00 38.67  ? 68  GLU C CG  1 
ATOM   6964  C  CD  . GLU C 1 89  ? -57.646 -50.081 9.180   1.00 51.30  ? 68  GLU C CD  1 
ATOM   6965  O  OE1 . GLU C 1 89  ? -58.042 -50.781 10.134  1.00 44.35  ? 68  GLU C OE1 1 
ATOM   6966  O  OE2 . GLU C 1 89  ? -57.997 -48.887 9.031   1.00 37.69  ? 68  GLU C OE2 1 
ATOM   6967  N  N   . ASP C 1 90  ? -54.448 -54.971 7.343   1.00 36.06  ? 69  ASP C N   1 
ATOM   6968  C  CA  . ASP C 1 90  ? -53.592 -56.098 7.708   1.00 33.20  ? 69  ASP C CA  1 
ATOM   6969  C  C   . ASP C 1 90  ? -52.131 -55.852 7.355   1.00 40.37  ? 69  ASP C C   1 
ATOM   6970  O  O   . ASP C 1 90  ? -51.257 -56.582 7.842   1.00 36.58  ? 69  ASP C O   1 
ATOM   6971  C  CB  . ASP C 1 90  ? -54.045 -57.381 6.995   1.00 33.75  ? 69  ASP C CB  1 
ATOM   6972  C  CG  . ASP C 1 90  ? -55.406 -57.861 7.454   1.00 54.91  ? 69  ASP C CG  1 
ATOM   6973  O  OD1 . ASP C 1 90  ? -55.835 -57.457 8.557   1.00 53.57  ? 69  ASP C OD1 1 
ATOM   6974  O  OD2 . ASP C 1 90  ? -56.038 -58.649 6.712   1.00 68.27  ? 69  ASP C OD2 1 
ATOM   6975  N  N   . VAL C 1 91  ? -51.837 -54.895 6.477   1.00 32.04  ? 70  VAL C N   1 
ATOM   6976  C  CA  . VAL C 1 91  ? -50.441 -54.633 6.143   1.00 32.58  ? 70  VAL C CA  1 
ATOM   6977  C  C   . VAL C 1 91  ? -50.058 -53.155 6.271   1.00 30.80  ? 70  VAL C C   1 
ATOM   6978  O  O   . VAL C 1 91  ? -48.880 -52.819 6.145   1.00 33.03  ? 70  VAL C O   1 
ATOM   6979  C  CB  . VAL C 1 91  ? -50.083 -55.147 4.731   1.00 37.72  ? 70  VAL C CB  1 
ATOM   6980  C  CG1 . VAL C 1 91  ? -50.318 -56.657 4.600   1.00 39.51  ? 70  VAL C CG1 1 
ATOM   6981  C  CG2 . VAL C 1 91  ? -50.831 -54.377 3.662   1.00 32.54  ? 70  VAL C CG2 1 
ATOM   6982  N  N   . MET C 1 92  ? -51.019 -52.255 6.500   1.00 29.19  ? 71  MET C N   1 
ATOM   6983  C  CA  . MET C 1 92  ? -50.724 -50.823 6.604   1.00 28.16  ? 71  MET C CA  1 
ATOM   6984  C  C   . MET C 1 92  ? -51.162 -50.283 7.955   1.00 27.77  ? 71  MET C C   1 
ATOM   6985  O  O   . MET C 1 92  ? -52.243 -50.618 8.436   1.00 32.68  ? 71  MET C O   1 
ATOM   6986  C  CB  . MET C 1 92  ? -51.455 -49.984 5.513   1.00 29.65  ? 71  MET C CB  1 
ATOM   6987  C  CG  . MET C 1 92  ? -51.004 -50.246 4.080   1.00 31.81  ? 71  MET C CG  1 
ATOM   6988  S  SD  . MET C 1 92  ? -49.297 -49.799 3.824   1.00 33.47  ? 71  MET C SD  1 
ATOM   6989  C  CE  . MET C 1 92  ? -48.576 -51.297 3.147   1.00 30.54  ? 71  MET C CE  1 
ATOM   6990  N  N   . GLN C 1 93  ? -50.351 -49.394 8.534   1.00 26.73  ? 72  GLN C N   1 
ATOM   6991  C  CA  . GLN C 1 93  ? -50.734 -48.652 9.729   1.00 29.54  ? 72  GLN C CA  1 
ATOM   6992  C  C   . GLN C 1 93  ? -50.543 -47.171 9.457   1.00 27.81  ? 72  GLN C C   1 
ATOM   6993  O  O   . GLN C 1 93  ? -49.810 -46.797 8.536   1.00 29.13  ? 72  GLN C O   1 
ATOM   6994  C  CB  . GLN C 1 93  ? -49.879 -49.030 10.940  1.00 30.88  ? 72  GLN C CB  1 
ATOM   6995  C  CG  . GLN C 1 93  ? -48.483 -48.436 10.870  1.00 30.20  ? 72  GLN C CG  1 
ATOM   6996  C  CD  . GLN C 1 93  ? -47.619 -48.807 12.072  1.00 44.85  ? 72  GLN C CD  1 
ATOM   6997  O  OE1 . GLN C 1 93  ? -47.605 -49.957 12.511  1.00 40.85  ? 72  GLN C OE1 1 
ATOM   6998  N  NE2 . GLN C 1 93  ? -46.903 -47.825 12.612  1.00 34.38  ? 72  GLN C NE2 1 
ATOM   6999  N  N   . ARG C 1 94  ? -51.156 -46.321 10.306  1.00 21.90  ? 73  ARG C N   1 
ATOM   7000  C  CA  . ARG C 1 94  ? -50.996 -44.878 10.154  1.00 22.75  ? 73  ARG C CA  1 
ATOM   7001  C  C   . ARG C 1 94  ? -50.105 -44.223 11.206  1.00 29.12  ? 73  ARG C C   1 
ATOM   7002  O  O   . ARG C 1 94  ? -49.576 -43.126 10.949  1.00 27.10  ? 73  ARG C O   1 
ATOM   7003  C  CB  . ARG C 1 94  ? -52.359 -44.170 10.167  1.00 27.33  ? 73  ARG C CB  1 
ATOM   7004  C  CG  . ARG C 1 94  ? -53.307 -44.667 9.049   1.00 23.15  ? 73  ARG C CG  1 
ATOM   7005  C  CD  . ARG C 1 94  ? -52.660 -44.658 7.638   1.00 26.26  ? 73  ARG C CD  1 
ATOM   7006  N  NE  . ARG C 1 94  ? -53.641 -44.977 6.592   1.00 29.57  ? 73  ARG C NE  1 
ATOM   7007  C  CZ  . ARG C 1 94  ? -54.528 -44.111 6.110   1.00 28.13  ? 73  ARG C CZ  1 
ATOM   7008  N  NH1 . ARG C 1 94  ? -54.518 -42.836 6.469   1.00 24.48  ? 73  ARG C NH1 1 
ATOM   7009  N  NH2 . ARG C 1 94  ? -55.474 -44.539 5.272   1.00 25.45  ? 73  ARG C NH2 1 
ATOM   7010  N  N   . GLU C 1 95  ? -49.903 -44.850 12.364  1.00 28.93  ? 74  GLU C N   1 
ATOM   7011  C  CA  . GLU C 1 95  ? -49.069 -44.202 13.382  1.00 29.31  ? 74  GLU C CA  1 
ATOM   7012  C  C   . GLU C 1 95  ? -47.667 -43.946 12.848  1.00 30.81  ? 74  GLU C C   1 
ATOM   7013  O  O   . GLU C 1 95  ? -47.007 -44.856 12.340  1.00 31.28  ? 74  GLU C O   1 
ATOM   7014  C  CB  . GLU C 1 95  ? -48.991 -45.056 14.647  1.00 34.65  ? 74  GLU C CB  1 
ATOM   7015  C  CG  . GLU C 1 95  ? -48.174 -44.394 15.748  1.00 37.70  ? 74  GLU C CG  1 
ATOM   7016  C  CD  . GLU C 1 95  ? -48.186 -45.220 17.038  1.00 68.30  ? 74  GLU C CD  1 
ATOM   7017  O  OE1 . GLU C 1 95  ? -48.127 -46.472 16.954  1.00 63.87  ? 74  GLU C OE1 1 
ATOM   7018  O  OE2 . GLU C 1 95  ? -48.269 -44.620 18.132  1.00 77.86  ? 74  GLU C OE2 1 
ATOM   7019  N  N   . GLY C 1 96  ? -47.221 -42.699 12.958  1.00 32.98  ? 75  GLY C N   1 
ATOM   7020  C  CA  . GLY C 1 96  ? -45.917 -42.301 12.476  1.00 33.97  ? 75  GLY C CA  1 
ATOM   7021  C  C   . GLY C 1 96  ? -45.776 -42.100 10.975  1.00 34.10  ? 75  GLY C C   1 
ATOM   7022  O  O   . GLY C 1 96  ? -44.684 -41.750 10.527  1.00 32.36  ? 75  GLY C O   1 
ATOM   7023  N  N   . ALA C 1 97  ? -46.836 -42.295 10.177  1.00 31.62  ? 76  ALA C N   1 
ATOM   7024  C  CA  . ALA C 1 97  ? -46.707 -42.162 8.721   1.00 32.35  ? 76  ALA C CA  1 
ATOM   7025  C  C   . ALA C 1 97  ? -46.636 -40.701 8.289   1.00 28.48  ? 76  ALA C C   1 
ATOM   7026  O  O   . ALA C 1 97  ? -45.825 -40.334 7.428   1.00 27.08  ? 76  ALA C O   1 
ATOM   7027  C  CB  . ALA C 1 97  ? -47.881 -42.844 8.005   1.00 27.79  ? 76  ALA C CB  1 
ATOM   7028  N  N   . MET C 1 98  ? -47.496 -39.870 8.839   1.00 23.88  ? 77  MET C N   1 
ATOM   7029  C  CA  . MET C 1 98  ? -47.498 -38.449 8.495   1.00 28.10  ? 77  MET C CA  1 
ATOM   7030  C  C   . MET C 1 98  ? -46.388 -37.732 9.267   1.00 33.16  ? 77  MET C C   1 
ATOM   7031  O  O   . MET C 1 98  ? -46.321 -37.853 10.492  1.00 32.62  ? 77  MET C O   1 
ATOM   7032  C  CB  . MET C 1 98  ? -48.848 -37.815 8.830   1.00 30.34  ? 77  MET C CB  1 
ATOM   7033  C  CG  . MET C 1 98  ? -48.949 -36.339 8.474   1.00 31.45  ? 77  MET C CG  1 
ATOM   7034  S  SD  . MET C 1 98  ? -49.012 -36.046 6.685   1.00 32.59  ? 77  MET C SD  1 
ATOM   7035  C  CE  . MET C 1 98  ? -50.732 -36.491 6.334   1.00 28.05  ? 77  MET C CE  1 
ATOM   7036  N  N   . PRO C 1 99  ? -45.521 -36.981 8.601   1.00 29.74  ? 78  PRO C N   1 
ATOM   7037  C  CA  . PRO C 1 99  ? -44.507 -36.189 9.320   1.00 29.59  ? 78  PRO C CA  1 
ATOM   7038  C  C   . PRO C 1 99  ? -45.153 -35.167 10.241  1.00 33.20  ? 78  PRO C C   1 
ATOM   7039  O  O   . PRO C 1 99  ? -46.059 -34.415 9.830   1.00 30.28  ? 78  PRO C O   1 
ATOM   7040  C  CB  . PRO C 1 99  ? -43.715 -35.507 8.192   1.00 32.70  ? 78  PRO C CB  1 
ATOM   7041  C  CG  . PRO C 1 99  ? -44.519 -35.696 6.963   1.00 37.23  ? 78  PRO C CG  1 
ATOM   7042  C  CD  . PRO C 1 99  ? -45.357 -36.900 7.140   1.00 32.61  ? 78  PRO C CD  1 
ATOM   7043  N  N   . PRO C 1 100 ? -44.722 -35.134 11.507  1.00 31.07  ? 79  PRO C N   1 
ATOM   7044  C  CA  . PRO C 1 100 ? -45.359 -34.246 12.499  1.00 26.35  ? 79  PRO C CA  1 
ATOM   7045  C  C   . PRO C 1 100 ? -45.388 -32.784 12.117  1.00 25.53  ? 79  PRO C C   1 
ATOM   7046  O  O   . PRO C 1 100 ? -46.275 -32.061 12.587  1.00 28.52  ? 79  PRO C O   1 
ATOM   7047  C  CB  . PRO C 1 100 ? -44.516 -34.464 13.772  1.00 33.82  ? 79  PRO C CB  1 
ATOM   7048  C  CG  . PRO C 1 100 ? -43.835 -35.786 13.599  1.00 33.53  ? 79  PRO C CG  1 
ATOM   7049  C  CD  . PRO C 1 100 ? -43.758 -36.088 12.112  1.00 31.64  ? 79  PRO C CD  1 
ATOM   7050  N  N   . VAL C 1 101 ? -44.428 -32.299 11.325  1.00 26.60  ? 80  VAL C N   1 
ATOM   7051  C  CA  . VAL C 1 101 ? -44.441 -30.875 10.987  1.00 26.08  ? 80  VAL C CA  1 
ATOM   7052  C  C   . VAL C 1 101 ? -45.673 -30.531 10.150  1.00 25.73  ? 80  VAL C C   1 
ATOM   7053  O  O   . VAL C 1 101 ? -46.100 -29.368 10.117  1.00 31.50  ? 80  VAL C O   1 
ATOM   7054  C  CB  . VAL C 1 101 ? -43.133 -30.463 10.260  1.00 33.50  ? 80  VAL C CB  1 
ATOM   7055  C  CG1 . VAL C 1 101 ? -43.036 -31.124 8.849   1.00 30.88  ? 80  VAL C CG1 1 
ATOM   7056  C  CG2 . VAL C 1 101 ? -43.036 -28.940 10.157  1.00 39.80  ? 80  VAL C CG2 1 
ATOM   7057  N  N   . ILE C 1 102 ? -46.258 -31.523 9.464   1.00 27.02  ? 81  ILE C N   1 
ATOM   7058  C  CA  . ILE C 1 102 ? -47.541 -31.355 8.783   1.00 25.42  ? 81  ILE C CA  1 
ATOM   7059  C  C   . ILE C 1 102 ? -48.671 -31.758 9.728   1.00 26.43  ? 81  ILE C C   1 
ATOM   7060  O  O   . ILE C 1 102 ? -49.593 -30.970 10.006  1.00 29.48  ? 81  ILE C O   1 
ATOM   7061  C  CB  . ILE C 1 102 ? -47.583 -32.195 7.492   1.00 27.86  ? 81  ILE C CB  1 
ATOM   7062  C  CG1 . ILE C 1 102 ? -46.494 -31.720 6.530   1.00 29.12  ? 81  ILE C CG1 1 
ATOM   7063  C  CG2 . ILE C 1 102 ? -48.955 -32.077 6.806   1.00 29.52  ? 81  ILE C CG2 1 
ATOM   7064  C  CD1 . ILE C 1 102 ? -46.494 -32.438 5.204   1.00 37.75  ? 81  ILE C CD1 1 
ATOM   7065  N  N   . GLY C 1 103 ? -48.606 -32.993 10.226  1.00 24.48  ? 82  GLY C N   1 
ATOM   7066  C  CA  . GLY C 1 103 ? -49.737 -33.551 10.944  1.00 29.23  ? 82  GLY C CA  1 
ATOM   7067  C  C   . GLY C 1 103 ? -50.058 -32.788 12.213  1.00 30.52  ? 82  GLY C C   1 
ATOM   7068  O  O   . GLY C 1 103 ? -51.218 -32.501 12.492  1.00 26.77  ? 82  GLY C O   1 
ATOM   7069  N  N   . ASP C 1 104 ? -49.027 -32.470 13.019  1.00 24.25  ? 83  ASP C N   1 
ATOM   7070  C  CA  . ASP C 1 104 ? -49.284 -31.784 14.287  1.00 30.63  ? 83  ASP C CA  1 
ATOM   7071  C  C   . ASP C 1 104 ? -49.928 -30.423 14.072  1.00 29.45  ? 83  ASP C C   1 
ATOM   7072  O  O   . ASP C 1 104 ? -50.682 -29.957 14.932  1.00 30.06  ? 83  ASP C O   1 
ATOM   7073  C  CB  . ASP C 1 104 ? -47.992 -31.643 15.107  1.00 30.86  ? 83  ASP C CB  1 
ATOM   7074  C  CG  . ASP C 1 104 ? -47.529 -32.970 15.686  1.00 39.38  ? 83  ASP C CG  1 
ATOM   7075  O  OD1 . ASP C 1 104 ? -48.222 -33.990 15.472  1.00 34.47  ? 83  ASP C OD1 1 
ATOM   7076  O  OD2 . ASP C 1 104 ? -46.464 -33.006 16.339  1.00 36.80  ? 83  ASP C OD2 1 
ATOM   7077  N  N   . ALA C 1 105 ? -49.641 -29.762 12.943  1.00 26.22  ? 84  ALA C N   1 
ATOM   7078  C  CA  . ALA C 1 105 ? -50.290 -28.490 12.659  1.00 24.55  ? 84  ALA C CA  1 
ATOM   7079  C  C   . ALA C 1 105 ? -51.695 -28.709 12.124  1.00 27.20  ? 84  ALA C C   1 
ATOM   7080  O  O   . ALA C 1 105 ? -52.650 -28.108 12.623  1.00 26.86  ? 84  ALA C O   1 
ATOM   7081  C  CB  . ALA C 1 105 ? -49.467 -27.674 11.647  1.00 28.27  ? 84  ALA C CB  1 
ATOM   7082  N  N   . LEU C 1 106 ? -51.836 -29.585 11.124  1.00 25.81  ? 85  LEU C N   1 
ATOM   7083  C  CA  . LEU C 1 106 ? -53.112 -29.713 10.415  1.00 23.30  ? 85  LEU C CA  1 
ATOM   7084  C  C   . LEU C 1 106 ? -54.194 -30.367 11.285  1.00 27.23  ? 85  LEU C C   1 
ATOM   7085  O  O   . LEU C 1 106 ? -55.317 -29.857 11.363  1.00 27.25  ? 85  LEU C O   1 
ATOM   7086  C  CB  . LEU C 1 106 ? -52.914 -30.511 9.130   1.00 24.38  ? 85  LEU C CB  1 
ATOM   7087  C  CG  . LEU C 1 106 ? -54.206 -30.657 8.335   1.00 27.15  ? 85  LEU C CG  1 
ATOM   7088  C  CD1 . LEU C 1 106 ? -54.761 -29.272 7.906   1.00 27.89  ? 85  LEU C CD1 1 
ATOM   7089  C  CD2 . LEU C 1 106 ? -53.882 -31.537 7.134   1.00 26.88  ? 85  LEU C CD2 1 
ATOM   7090  N  N   . VAL C 1 107 ? -53.898 -31.508 11.909  1.00 24.13  ? 86  VAL C N   1 
ATOM   7091  C  CA  . VAL C 1 107 ? -54.921 -32.266 12.626  1.00 25.49  ? 86  VAL C CA  1 
ATOM   7092  C  C   . VAL C 1 107 ? -54.672 -32.346 14.126  1.00 32.72  ? 86  VAL C C   1 
ATOM   7093  O  O   . VAL C 1 107 ? -55.606 -32.694 14.863  1.00 28.52  ? 86  VAL C O   1 
ATOM   7094  C  CB  . VAL C 1 107 ? -55.119 -33.689 12.041  1.00 28.10  ? 86  VAL C CB  1 
ATOM   7095  C  CG1 . VAL C 1 107 ? -55.343 -33.590 10.529  1.00 26.22  ? 86  VAL C CG1 1 
ATOM   7096  C  CG2 . VAL C 1 107 ? -53.941 -34.673 12.370  1.00 24.85  ? 86  VAL C CG2 1 
ATOM   7097  N  N   . GLY C 1 108 ? -53.471 -32.000 14.599  1.00 30.22  ? 87  GLY C N   1 
ATOM   7098  C  CA  . GLY C 1 108 ? -53.144 -31.922 16.014  1.00 26.48  ? 87  GLY C CA  1 
ATOM   7099  C  C   . GLY C 1 108 ? -52.671 -33.245 16.590  1.00 33.08  ? 87  GLY C C   1 
ATOM   7100  O  O   . GLY C 1 108 ? -52.877 -34.321 16.030  1.00 31.42  ? 87  GLY C O   1 
ATOM   7101  N  N   . LYS C 1 109 ? -52.037 -33.160 17.758  1.00 29.69  ? 88  LYS C N   1 
ATOM   7102  C  CA  . LYS C 1 109 ? -51.471 -34.352 18.383  1.00 32.74  ? 88  LYS C CA  1 
ATOM   7103  C  C   . LYS C 1 109 ? -52.556 -35.297 18.897  1.00 28.84  ? 88  LYS C C   1 
ATOM   7104  O  O   . LYS C 1 109 ? -53.607 -34.864 19.368  1.00 30.52  ? 88  LYS C O   1 
ATOM   7105  C  CB  . LYS C 1 109 ? -50.546 -33.934 19.536  1.00 35.76  ? 88  LYS C CB  1 
ATOM   7106  C  CG  . LYS C 1 109 ? -49.366 -33.032 19.081  1.00 33.68  ? 88  LYS C CG  1 
ATOM   7107  C  CD  . LYS C 1 109 ? -48.371 -32.836 20.255  1.00 39.16  ? 88  LYS C CD  1 
ATOM   7108  C  CE  . LYS C 1 109 ? -47.059 -32.258 19.814  1.00 43.23  ? 88  LYS C CE  1 
ATOM   7109  N  NZ  . LYS C 1 109 ? -47.120 -30.790 19.948  1.00 52.56  ? 88  LYS C NZ  1 
ATOM   7110  N  N   . GLY C 1 110 ? -52.290 -36.603 18.811  1.00 28.31  ? 89  GLY C N   1 
ATOM   7111  C  CA  . GLY C 1 110 ? -53.258 -37.583 19.298  1.00 34.29  ? 89  GLY C CA  1 
ATOM   7112  C  C   . GLY C 1 110 ? -54.558 -37.710 18.527  1.00 36.56  ? 89  GLY C C   1 
ATOM   7113  O  O   . GLY C 1 110 ? -55.477 -38.393 19.001  1.00 32.21  ? 89  GLY C O   1 
ATOM   7114  N  N   . ALA C 1 111 ? -54.666 -37.090 17.352  1.00 33.23  ? 90  ALA C N   1 
ATOM   7115  C  CA  . ALA C 1 111 ? -55.888 -37.131 16.553  1.00 29.01  ? 90  ALA C CA  1 
ATOM   7116  C  C   . ALA C 1 111 ? -56.140 -38.522 15.974  1.00 35.34  ? 90  ALA C C   1 
ATOM   7117  O  O   . ALA C 1 111 ? -55.229 -39.339 15.804  1.00 25.98  ? 90  ALA C O   1 
ATOM   7118  C  CB  . ALA C 1 111 ? -55.800 -36.099 15.428  1.00 29.94  ? 90  ALA C CB  1 
ATOM   7119  N  N   . VAL C 1 112 ? -57.411 -38.759 15.609  1.00 29.27  ? 91  VAL C N   1 
ATOM   7120  C  CA  . VAL C 1 112 ? -57.853 -40.042 15.069  1.00 25.58  ? 91  VAL C CA  1 
ATOM   7121  C  C   . VAL C 1 112 ? -56.998 -40.497 13.879  1.00 30.89  ? 91  VAL C C   1 
ATOM   7122  O  O   . VAL C 1 112 ? -56.800 -41.701 13.669  1.00 25.68  ? 91  VAL C O   1 
ATOM   7123  C  CB  . VAL C 1 112 ? -59.353 -39.931 14.700  1.00 27.93  ? 91  VAL C CB  1 
ATOM   7124  C  CG1 . VAL C 1 112 ? -59.568 -38.854 13.601  1.00 27.92  ? 91  VAL C CG1 1 
ATOM   7125  C  CG2 . VAL C 1 112 ? -59.917 -41.303 14.274  1.00 31.83  ? 91  VAL C CG2 1 
ATOM   7126  N  N   . HIS C 1 113 ? -56.459 -39.549 13.105  1.00 24.85  ? 92  HIS C N   1 
ATOM   7127  C  CA  . HIS C 1 113 ? -55.673 -39.880 11.916  1.00 24.33  ? 92  HIS C CA  1 
ATOM   7128  C  C   . HIS C 1 113 ? -54.455 -40.736 12.249  1.00 27.45  ? 92  HIS C C   1 
ATOM   7129  O  O   . HIS C 1 113 ? -53.993 -41.532 11.418  1.00 29.61  ? 92  HIS C O   1 
ATOM   7130  C  CB  . HIS C 1 113 ? -55.207 -38.581 11.245  1.00 26.16  ? 92  HIS C CB  1 
ATOM   7131  C  CG  . HIS C 1 113 ? -56.305 -37.604 10.954  1.00 25.10  ? 92  HIS C CG  1 
ATOM   7132  N  ND1 . HIS C 1 113 ? -57.041 -36.986 11.948  1.00 27.39  ? 92  HIS C ND1 1 
ATOM   7133  C  CD2 . HIS C 1 113 ? -56.767 -37.107 9.781   1.00 26.04  ? 92  HIS C CD2 1 
ATOM   7134  C  CE1 . HIS C 1 113 ? -57.912 -36.156 11.397  1.00 30.61  ? 92  HIS C CE1 1 
ATOM   7135  N  NE2 . HIS C 1 113 ? -57.779 -36.227 10.081  1.00 24.91  ? 92  HIS C NE2 1 
ATOM   7136  N  N   . ASN C 1 114 ? -53.898 -40.562 13.431  1.00 30.03  ? 93  ASN C N   1 
ATOM   7137  C  CA  . ASN C 1 114 ? -52.661 -41.244 13.800  1.00 30.72  ? 93  ASN C CA  1 
ATOM   7138  C  C   . ASN C 1 114 ? -52.899 -42.593 14.462  1.00 36.25  ? 93  ASN C C   1 
ATOM   7139  O  O   . ASN C 1 114 ? -51.923 -43.277 14.791  1.00 37.96  ? 93  ASN C O   1 
ATOM   7140  C  CB  . ASN C 1 114 ? -51.842 -40.349 14.735  1.00 30.86  ? 93  ASN C CB  1 
ATOM   7141  C  CG  . ASN C 1 114 ? -51.559 -39.004 14.136  1.00 50.87  ? 93  ASN C CG  1 
ATOM   7142  O  OD1 . ASN C 1 114 ? -51.302 -38.889 12.926  1.00 56.17  ? 93  ASN C OD1 1 
ATOM   7143  N  ND2 . ASN C 1 114 ? -51.615 -37.961 14.968  1.00 56.48  ? 93  ASN C ND2 1 
ATOM   7144  N  N   . LEU C 1 115 ? -54.155 -43.001 14.644  1.00 29.22  ? 94  LEU C N   1 
ATOM   7145  C  CA  . LEU C 1 115 ? -54.498 -44.164 15.459  1.00 26.32  ? 94  LEU C CA  1 
ATOM   7146  C  C   . LEU C 1 115 ? -54.633 -45.421 14.617  1.00 29.81  ? 94  LEU C C   1 
ATOM   7147  O  O   . LEU C 1 115 ? -55.052 -45.375 13.457  1.00 27.60  ? 94  LEU C O   1 
ATOM   7148  C  CB  . LEU C 1 115 ? -55.814 -43.939 16.222  1.00 26.16  ? 94  LEU C CB  1 
ATOM   7149  C  CG  . LEU C 1 115 ? -55.857 -42.710 17.114  1.00 29.47  ? 94  LEU C CG  1 
ATOM   7150  C  CD1 . LEU C 1 115 ? -57.228 -42.581 17.809  1.00 30.79  ? 94  LEU C CD1 1 
ATOM   7151  C  CD2 . LEU C 1 115 ? -54.699 -42.759 18.138  1.00 35.52  ? 94  LEU C CD2 1 
ATOM   7152  N  N   . ASP C 1 116 ? -54.312 -46.568 15.230  1.00 24.77  ? 95  ASP C N   1 
ATOM   7153  C  CA  . ASP C 1 116 ? -54.475 -47.854 14.590  1.00 25.82  ? 95  ASP C CA  1 
ATOM   7154  C  C   . ASP C 1 116 ? -55.316 -48.773 15.465  1.00 32.95  ? 95  ASP C C   1 
ATOM   7155  O  O   . ASP C 1 116 ? -55.631 -48.464 16.615  1.00 31.31  ? 95  ASP C O   1 
ATOM   7156  C  CB  . ASP C 1 116 ? -53.116 -48.485 14.274  1.00 30.17  ? 95  ASP C CB  1 
ATOM   7157  C  CG  . ASP C 1 116 ? -52.341 -47.669 13.254  1.00 35.15  ? 95  ASP C CG  1 
ATOM   7158  O  OD1 . ASP C 1 116 ? -52.912 -47.393 12.166  1.00 35.97  ? 95  ASP C OD1 1 
ATOM   7159  O  OD2 . ASP C 1 116 ? -51.190 -47.267 13.550  1.00 32.98  ? 95  ASP C OD2 1 
ATOM   7160  N  N   . GLY C 1 117 ? -55.728 -49.883 14.866  1.00 31.44  ? 96  GLY C N   1 
ATOM   7161  C  CA  . GLY C 1 117 ? -56.393 -50.991 15.525  1.00 33.40  ? 96  GLY C CA  1 
ATOM   7162  C  C   . GLY C 1 117 ? -57.697 -50.590 16.184  1.00 34.45  ? 96  GLY C C   1 
ATOM   7163  O  O   . GLY C 1 117 ? -58.453 -49.734 15.703  1.00 33.06  ? 96  GLY C O   1 
ATOM   7164  N  N   . GLU C 1 118 ? -57.962 -51.219 17.328  1.00 34.80  ? 97  GLU C N   1 
ATOM   7165  C  CA  . GLU C 1 118 ? -59.222 -50.983 18.026  1.00 31.71  ? 97  GLU C CA  1 
ATOM   7166  C  C   . GLU C 1 118 ? -59.322 -49.564 18.574  1.00 33.32  ? 97  GLU C C   1 
ATOM   7167  O  O   . GLU C 1 118 ? -60.425 -48.992 18.602  1.00 34.65  ? 97  GLU C O   1 
ATOM   7168  C  CB  . GLU C 1 118 ? -59.399 -52.010 19.151  1.00 41.98  ? 97  GLU C CB  1 
ATOM   7169  C  CG  . GLU C 1 118 ? -60.536 -51.706 20.111  1.00 51.55  ? 97  GLU C CG  1 
ATOM   7170  C  CD  . GLU C 1 118 ? -61.858 -52.344 19.701  1.00 72.25  ? 97  GLU C CD  1 
ATOM   7171  O  OE1 . GLU C 1 118 ? -62.120 -52.470 18.482  1.00 68.52  ? 97  GLU C OE1 1 
ATOM   7172  O  OE2 . GLU C 1 118 ? -62.637 -52.727 20.607  1.00 85.83  ? 97  GLU C OE2 1 
ATOM   7173  N  N   . GLU C 1 119 ? -58.212 -48.976 19.041  1.00 31.12  ? 98  GLU C N   1 
ATOM   7174  C  CA  . GLU C 1 119 ? -58.316 -47.585 19.483  1.00 29.91  ? 98  GLU C CA  1 
ATOM   7175  C  C   . GLU C 1 119 ? -58.772 -46.689 18.332  1.00 34.52  ? 98  GLU C C   1 
ATOM   7176  O  O   . GLU C 1 119 ? -59.550 -45.751 18.537  1.00 32.70  ? 98  GLU C O   1 
ATOM   7177  C  CB  . GLU C 1 119 ? -56.994 -47.083 20.066  1.00 39.67  ? 98  GLU C CB  1 
ATOM   7178  C  CG  . GLU C 1 119 ? -56.610 -47.746 21.409  1.00 62.45  ? 98  GLU C CG  1 
ATOM   7179  C  CD  . GLU C 1 119 ? -57.489 -47.353 22.621  1.00 65.04  ? 98  GLU C CD  1 
ATOM   7180  O  OE1 . GLU C 1 119 ? -58.436 -46.535 22.494  1.00 46.84  ? 98  GLU C OE1 1 
ATOM   7181  O  OE2 . GLU C 1 119 ? -57.213 -47.872 23.729  1.00 60.84  ? 98  GLU C OE2 1 
ATOM   7182  N  N   . HIS C 1 120 ? -58.346 -46.992 17.109  1.00 28.93  ? 99  HIS C N   1 
ATOM   7183  C  CA  . HIS C 1 120 ? -58.838 -46.197 15.980  1.00 32.65  ? 99  HIS C CA  1 
ATOM   7184  C  C   . HIS C 1 120 ? -60.313 -46.473 15.711  1.00 29.65  ? 99  HIS C C   1 
ATOM   7185  O  O   . HIS C 1 120 ? -61.102 -45.538 15.509  1.00 30.48  ? 99  HIS C O   1 
ATOM   7186  C  CB  . HIS C 1 120 ? -58.054 -46.477 14.716  1.00 29.71  ? 99  HIS C CB  1 
ATOM   7187  C  CG  . HIS C 1 120 ? -58.663 -45.822 13.519  1.00 30.43  ? 99  HIS C CG  1 
ATOM   7188  N  ND1 . HIS C 1 120 ? -59.327 -46.524 12.531  1.00 28.93  ? 99  HIS C ND1 1 
ATOM   7189  C  CD2 . HIS C 1 120 ? -58.759 -44.516 13.187  1.00 25.66  ? 99  HIS C CD2 1 
ATOM   7190  C  CE1 . HIS C 1 120 ? -59.773 -45.674 11.622  1.00 28.20  ? 99  HIS C CE1 1 
ATOM   7191  N  NE2 . HIS C 1 120 ? -59.446 -44.447 12.001  1.00 29.16  ? 99  HIS C NE2 1 
ATOM   7192  N  N   . LYS C 1 121 ? -60.694 -47.752 15.672  1.00 26.96  ? 100 LYS C N   1 
ATOM   7193  C  CA  . LYS C 1 121 ? -62.089 -48.106 15.408  1.00 31.14  ? 100 LYS C CA  1 
ATOM   7194  C  C   . LYS C 1 121 ? -63.032 -47.397 16.383  1.00 36.79  ? 100 LYS C C   1 
ATOM   7195  O  O   . LYS C 1 121 ? -64.042 -46.815 15.979  1.00 32.68  ? 100 LYS C O   1 
ATOM   7196  C  CB  . LYS C 1 121 ? -62.246 -49.626 15.487  1.00 34.32  ? 100 LYS C CB  1 
ATOM   7197  C  CG  . LYS C 1 121 ? -63.595 -50.171 15.081  1.00 43.33  ? 100 LYS C CG  1 
ATOM   7198  C  CD  . LYS C 1 121 ? -63.926 -51.413 15.926  1.00 60.20  ? 100 LYS C CD  1 
ATOM   7199  C  CE  . LYS C 1 121 ? -64.833 -52.390 15.194  1.00 67.64  ? 100 LYS C CE  1 
ATOM   7200  N  NZ  . LYS C 1 121 ? -65.997 -51.714 14.567  1.00 69.93  ? 100 LYS C NZ  1 
ATOM   7201  N  N   . VAL C 1 122 ? -62.687 -47.391 17.673  1.00 35.11  ? 101 VAL C N   1 
ATOM   7202  C  CA  . VAL C 1 122 ? -63.570 -46.791 18.668  1.00 35.98  ? 101 VAL C CA  1 
ATOM   7203  C  C   . VAL C 1 122 ? -63.634 -45.272 18.507  1.00 30.26  ? 101 VAL C C   1 
ATOM   7204  O  O   . VAL C 1 122 ? -64.702 -44.666 18.636  1.00 28.97  ? 101 VAL C O   1 
ATOM   7205  C  CB  . VAL C 1 122 ? -63.115 -47.205 20.081  1.00 37.58  ? 101 VAL C CB  1 
ATOM   7206  C  CG1 . VAL C 1 122 ? -63.733 -46.292 21.144  1.00 36.57  ? 101 VAL C CG1 1 
ATOM   7207  C  CG2 . VAL C 1 122 ? -63.494 -48.651 20.323  1.00 33.23  ? 101 VAL C CG2 1 
ATOM   7208  N  N   . ARG C 1 123 ? -62.497 -44.631 18.248  1.00 27.49  ? 102 ARG C N   1 
ATOM   7209  C  CA  . ARG C 1 123 ? -62.498 -43.180 18.070  1.00 32.72  ? 102 ARG C CA  1 
ATOM   7210  C  C   . ARG C 1 123 ? -63.225 -42.790 16.789  1.00 25.95  ? 102 ARG C C   1 
ATOM   7211  O  O   . ARG C 1 123 ? -64.021 -41.847 16.786  1.00 28.86  ? 102 ARG C O   1 
ATOM   7212  C  CB  . ARG C 1 123 ? -61.060 -42.639 18.052  1.00 30.06  ? 102 ARG C CB  1 
ATOM   7213  C  CG  . ARG C 1 123 ? -60.947 -41.137 17.685  1.00 33.57  ? 102 ARG C CG  1 
ATOM   7214  C  CD  . ARG C 1 123 ? -61.119 -40.183 18.885  1.00 31.08  ? 102 ARG C CD  1 
ATOM   7215  N  NE  . ARG C 1 123 ? -60.216 -40.552 19.976  1.00 37.09  ? 102 ARG C NE  1 
ATOM   7216  C  CZ  . ARG C 1 123 ? -58.951 -40.166 20.106  1.00 44.34  ? 102 ARG C CZ  1 
ATOM   7217  N  NH1 . ARG C 1 123 ? -58.394 -39.282 19.278  1.00 37.11  ? 102 ARG C NH1 1 
ATOM   7218  N  NH2 . ARG C 1 123 ? -58.223 -40.673 21.096  1.00 32.10  ? 102 ARG C NH2 1 
ATOM   7219  N  N   . LYS C 1 124 ? -62.971 -43.521 15.701  1.00 28.25  ? 103 LYS C N   1 
ATOM   7220  C  CA  . LYS C 1 124 ? -63.601 -43.213 14.413  1.00 26.77  ? 103 LYS C CA  1 
ATOM   7221  C  C   . LYS C 1 124 ? -65.117 -43.383 14.475  1.00 30.40  ? 103 LYS C C   1 
ATOM   7222  O  O   . LYS C 1 124 ? -65.861 -42.590 13.872  1.00 27.40  ? 103 LYS C O   1 
ATOM   7223  C  CB  . LYS C 1 124 ? -63.001 -44.092 13.315  1.00 29.76  ? 103 LYS C CB  1 
ATOM   7224  C  CG  . LYS C 1 124 ? -63.608 -43.873 11.878  1.00 26.70  ? 103 LYS C CG  1 
ATOM   7225  C  CD  . LYS C 1 124 ? -63.569 -42.376 11.469  1.00 25.08  ? 103 LYS C CD  1 
ATOM   7226  C  CE  . LYS C 1 124 ? -63.766 -42.193 9.947   1.00 26.97  ? 103 LYS C CE  1 
ATOM   7227  N  NZ  . LYS C 1 124 ? -62.724 -42.937 9.150   1.00 23.43  ? 103 LYS C NZ  1 
ATOM   7228  N  N   . ALA C 1 125 ? -65.598 -44.397 15.216  1.00 28.48  ? 104 ALA C N   1 
ATOM   7229  C  CA  . ALA C 1 125 ? -67.041 -44.600 15.308  1.00 27.01  ? 104 ALA C CA  1 
ATOM   7230  C  C   . ALA C 1 125 ? -67.720 -43.409 15.964  1.00 34.62  ? 104 ALA C C   1 
ATOM   7231  O  O   . ALA C 1 125 ? -68.817 -42.998 15.554  1.00 36.68  ? 104 ALA C O   1 
ATOM   7232  C  CB  . ALA C 1 125 ? -67.354 -45.891 16.083  1.00 29.91  ? 104 ALA C CB  1 
ATOM   7233  N  N   . GLN C 1 126 ? -67.083 -42.830 16.979  1.00 26.27  ? 105 GLN C N   1 
ATOM   7234  C  CA  . GLN C 1 126 ? -67.670 -41.663 17.622  1.00 29.10  ? 105 GLN C CA  1 
ATOM   7235  C  C   . GLN C 1 126 ? -67.596 -40.417 16.743  1.00 31.30  ? 105 GLN C C   1 
ATOM   7236  O  O   . GLN C 1 126 ? -68.457 -39.540 16.844  1.00 32.89  ? 105 GLN C O   1 
ATOM   7237  C  CB  . GLN C 1 126 ? -66.983 -41.421 18.954  1.00 32.58  ? 105 GLN C CB  1 
ATOM   7238  C  CG  . GLN C 1 126 ? -67.303 -42.516 19.971  1.00 30.93  ? 105 GLN C CG  1 
ATOM   7239  C  CD  . GLN C 1 126 ? -66.420 -42.413 21.205  1.00 33.11  ? 105 GLN C CD  1 
ATOM   7240  O  OE1 . GLN C 1 126 ? -66.700 -41.634 22.121  1.00 35.18  ? 105 GLN C OE1 1 
ATOM   7241  N  NE2 . GLN C 1 126 ? -65.304 -43.157 21.199  1.00 34.00  ? 105 GLN C NE2 1 
ATOM   7242  N  N   . MET C 1 127 ? -66.589 -40.310 15.884  1.00 30.02  ? 106 MET C N   1 
ATOM   7243  C  CA  . MET C 1 127 ? -66.530 -39.132 15.021  1.00 32.67  ? 106 MET C CA  1 
ATOM   7244  C  C   . MET C 1 127 ? -67.404 -39.294 13.775  1.00 27.81  ? 106 MET C C   1 
ATOM   7245  O  O   . MET C 1 127 ? -68.044 -38.329 13.341  1.00 28.62  ? 106 MET C O   1 
ATOM   7246  C  CB  . MET C 1 127 ? -65.071 -38.839 14.678  1.00 31.79  ? 106 MET C CB  1 
ATOM   7247  C  CG  . MET C 1 127 ? -64.299 -38.313 15.967  1.00 27.17  ? 106 MET C CG  1 
ATOM   7248  S  SD  . MET C 1 127 ? -62.612 -38.053 15.599  1.00 50.44  ? 106 MET C SD  1 
ATOM   7249  C  CE  . MET C 1 127 ? -62.749 -36.400 14.864  1.00 32.50  ? 106 MET C CE  1 
ATOM   7250  N  N   . ALA C 1 128 ? -67.466 -40.507 13.204  1.00 26.50  ? 107 ALA C N   1 
ATOM   7251  C  CA  . ALA C 1 128 ? -68.387 -40.763 12.098  1.00 26.60  ? 107 ALA C CA  1 
ATOM   7252  C  C   . ALA C 1 128 ? -69.834 -40.602 12.539  1.00 32.15  ? 107 ALA C C   1 
ATOM   7253  O  O   . ALA C 1 128 ? -70.669 -40.131 11.773  1.00 28.67  ? 107 ALA C O   1 
ATOM   7254  C  CB  . ALA C 1 128 ? -68.163 -42.168 11.531  1.00 27.05  ? 107 ALA C CB  1 
ATOM   7255  N  N   . ALA C 1 129 ? -70.156 -41.001 13.770  1.00 30.09  ? 108 ALA C N   1 
ATOM   7256  C  CA  . ALA C 1 129 ? -71.516 -40.803 14.258  1.00 29.24  ? 108 ALA C CA  1 
ATOM   7257  C  C   . ALA C 1 129 ? -71.937 -39.332 14.164  1.00 32.37  ? 108 ALA C C   1 
ATOM   7258  O  O   . ALA C 1 129 ? -73.124 -39.034 13.976  1.00 32.54  ? 108 ALA C O   1 
ATOM   7259  C  CB  . ALA C 1 129 ? -71.623 -41.305 15.706  1.00 33.80  ? 108 ALA C CB  1 
ATOM   7260  N  N   . MET C 1 130 ? -70.984 -38.396 14.276  1.00 30.57  ? 109 MET C N   1 
ATOM   7261  C  CA  . MET C 1 130 ? -71.302 -36.970 14.195  1.00 32.17  ? 109 MET C CA  1 
ATOM   7262  C  C   . MET C 1 130 ? -71.348 -36.446 12.753  1.00 34.49  ? 109 MET C C   1 
ATOM   7263  O  O   . MET C 1 130 ? -72.284 -35.741 12.381  1.00 30.70  ? 109 MET C O   1 
ATOM   7264  C  CB  . MET C 1 130 ? -70.283 -36.156 15.003  1.00 31.10  ? 109 MET C CB  1 
ATOM   7265  C  CG  . MET C 1 130 ? -70.302 -36.410 16.508  1.00 29.12  ? 109 MET C CG  1 
ATOM   7266  S  SD  . MET C 1 130 ? -71.929 -36.108 17.231  1.00 34.88  ? 109 MET C SD  1 
ATOM   7267  C  CE  . MET C 1 130 ? -72.441 -37.835 17.545  1.00 27.17  ? 109 MET C CE  1 
ATOM   7268  N  N   . ALA C 1 131 ? -70.338 -36.759 11.930  1.00 28.53  ? 110 ALA C N   1 
ATOM   7269  C  CA  . ALA C 1 131 ? -70.244 -36.133 10.607  1.00 27.03  ? 110 ALA C CA  1 
ATOM   7270  C  C   . ALA C 1 131 ? -70.946 -36.921 9.510   1.00 25.09  ? 110 ALA C C   1 
ATOM   7271  O  O   . ALA C 1 131 ? -71.363 -36.332 8.505   1.00 30.58  ? 110 ALA C O   1 
ATOM   7272  C  CB  . ALA C 1 131 ? -68.771 -35.943 10.213  1.00 28.20  ? 110 ALA C CB  1 
ATOM   7273  N  N   . TYR C 1 132 ? -71.093 -38.235 9.675   1.00 25.69  ? 111 TYR C N   1 
ATOM   7274  C  CA  . TYR C 1 132 ? -71.474 -39.099 8.563   1.00 23.19  ? 111 TYR C CA  1 
ATOM   7275  C  C   . TYR C 1 132 ? -72.934 -39.552 8.618   1.00 28.45  ? 111 TYR C C   1 
ATOM   7276  O  O   . TYR C 1 132 ? -73.422 -40.117 7.635   1.00 33.21  ? 111 TYR C O   1 
ATOM   7277  C  CB  . TYR C 1 132 ? -70.544 -40.314 8.533   1.00 26.50  ? 111 TYR C CB  1 
ATOM   7278  C  CG  . TYR C 1 132 ? -70.635 -41.214 7.324   1.00 28.22  ? 111 TYR C CG  1 
ATOM   7279  C  CD1 . TYR C 1 132 ? -70.155 -40.799 6.088   1.00 31.78  ? 111 TYR C CD1 1 
ATOM   7280  C  CD2 . TYR C 1 132 ? -71.147 -42.514 7.425   1.00 29.15  ? 111 TYR C CD2 1 
ATOM   7281  C  CE1 . TYR C 1 132 ? -70.215 -41.613 4.976   1.00 30.24  ? 111 TYR C CE1 1 
ATOM   7282  C  CE2 . TYR C 1 132 ? -71.209 -43.354 6.300   1.00 35.70  ? 111 TYR C CE2 1 
ATOM   7283  C  CZ  . TYR C 1 132 ? -70.725 -42.898 5.088   1.00 30.89  ? 111 TYR C CZ  1 
ATOM   7284  O  OH  . TYR C 1 132 ? -70.749 -43.677 3.934   1.00 36.45  ? 111 TYR C OH  1 
ATOM   7285  N  N   . GLU C 1 133 ? -73.637 -39.330 9.737   1.00 26.75  ? 112 GLU C N   1 
ATOM   7286  C  CA  . GLU C 1 133 ? -75.042 -39.741 9.821   1.00 32.68  ? 112 GLU C CA  1 
ATOM   7287  C  C   . GLU C 1 133 ? -75.952 -38.786 9.038   1.00 33.65  ? 112 GLU C C   1 
ATOM   7288  O  O   . GLU C 1 133 ? -75.890 -37.562 9.201   1.00 29.01  ? 112 GLU C O   1 
ATOM   7289  C  CB  . GLU C 1 133 ? -75.472 -39.857 11.287  1.00 29.37  ? 112 GLU C CB  1 
ATOM   7290  C  CG  . GLU C 1 133 ? -75.009 -41.188 11.857  1.00 42.46  ? 112 GLU C CG  1 
ATOM   7291  C  CD  . GLU C 1 133 ? -75.509 -42.366 10.988  1.00 82.37  ? 112 GLU C CD  1 
ATOM   7292  O  OE1 . GLU C 1 133 ? -76.748 -42.507 10.827  1.00 83.56  ? 112 GLU C OE1 1 
ATOM   7293  O  OE2 . GLU C 1 133 ? -74.672 -43.129 10.438  1.00 66.53  ? 112 GLU C OE2 1 
ATOM   7294  N  N   . ASP C 1 134 ? -76.801 -39.363 8.186   1.00 29.85  ? 113 ASP C N   1 
ATOM   7295  C  CA  . ASP C 1 134 ? -77.640 -38.562 7.297   1.00 33.88  ? 113 ASP C CA  1 
ATOM   7296  C  C   . ASP C 1 134 ? -78.472 -37.536 8.058   1.00 32.76  ? 113 ASP C C   1 
ATOM   7297  O  O   . ASP C 1 134 ? -78.670 -36.414 7.580   1.00 30.85  ? 113 ASP C O   1 
ATOM   7298  C  CB  . ASP C 1 134 ? -78.545 -39.477 6.464   1.00 31.83  ? 113 ASP C CB  1 
ATOM   7299  C  CG  . ASP C 1 134 ? -77.776 -40.239 5.399   1.00 42.35  ? 113 ASP C CG  1 
ATOM   7300  O  OD1 . ASP C 1 134 ? -76.689 -39.761 4.996   1.00 40.14  ? 113 ASP C OD1 1 
ATOM   7301  O  OD2 . ASP C 1 134 ? -78.259 -41.308 4.961   1.00 43.63  ? 113 ASP C OD2 1 
ATOM   7302  N  N   . GLU C 1 135 ? -78.939 -37.885 9.258   1.00 28.80  ? 114 GLU C N   1 
ATOM   7303  C  CA  . GLU C 1 135 ? -79.745 -36.946 10.021  1.00 34.72  ? 114 GLU C CA  1 
ATOM   7304  C  C   . GLU C 1 135 ? -78.930 -35.740 10.449  1.00 31.57  ? 114 GLU C C   1 
ATOM   7305  O  O   . GLU C 1 135 ? -79.463 -34.635 10.538  1.00 30.10  ? 114 GLU C O   1 
ATOM   7306  C  CB  . GLU C 1 135 ? -80.355 -37.626 11.255  1.00 35.61  ? 114 GLU C CB  1 
ATOM   7307  C  CG  . GLU C 1 135 ? -81.362 -38.715 10.923  1.00 56.33  ? 114 GLU C CG  1 
ATOM   7308  C  CD  . GLU C 1 135 ? -80.732 -40.103 10.705  1.00 88.64  ? 114 GLU C CD  1 
ATOM   7309  O  OE1 . GLU C 1 135 ? -79.480 -40.226 10.585  1.00 59.46  ? 114 GLU C OE1 1 
ATOM   7310  O  OE2 . GLU C 1 135 ? -81.513 -41.082 10.657  1.00 90.77  ? 114 GLU C OE2 1 
ATOM   7311  N  N   . ARG C 1 136 ? -77.653 -35.933 10.738  1.00 27.45  ? 115 ARG C N   1 
ATOM   7312  C  CA  . ARG C 1 136 ? -76.856 -34.802 11.172  1.00 26.10  ? 115 ARG C CA  1 
ATOM   7313  C  C   . ARG C 1 136 ? -76.428 -33.944 9.997   1.00 26.98  ? 115 ARG C C   1 
ATOM   7314  O  O   . ARG C 1 136 ? -76.343 -32.718 10.128  1.00 27.61  ? 115 ARG C O   1 
ATOM   7315  C  CB  . ARG C 1 136 ? -75.661 -35.307 11.967  1.00 33.85  ? 115 ARG C CB  1 
ATOM   7316  C  CG  . ARG C 1 136 ? -76.117 -35.959 13.260  1.00 37.38  ? 115 ARG C CG  1 
ATOM   7317  C  CD  . ARG C 1 136 ? -74.974 -36.130 14.226  1.00 40.76  ? 115 ARG C CD  1 
ATOM   7318  N  NE  . ARG C 1 136 ? -75.375 -36.805 15.457  1.00 38.76  ? 115 ARG C NE  1 
ATOM   7319  C  CZ  . ARG C 1 136 ? -75.658 -36.184 16.593  1.00 36.33  ? 115 ARG C CZ  1 
ATOM   7320  N  NH1 . ARG C 1 136 ? -75.636 -34.864 16.684  1.00 33.51  ? 115 ARG C NH1 1 
ATOM   7321  N  NH2 . ARG C 1 136 ? -75.947 -36.906 17.673  1.00 40.36  ? 115 ARG C NH2 1 
ATOM   7322  N  N   . VAL C 1 137 ? -76.220 -34.568 8.835   1.00 25.17  ? 116 VAL C N   1 
ATOM   7323  C  CA  . VAL C 1 137 ? -75.940 -33.813 7.615   1.00 25.91  ? 116 VAL C CA  1 
ATOM   7324  C  C   . VAL C 1 137 ? -77.138 -32.956 7.251   1.00 28.64  ? 116 VAL C C   1 
ATOM   7325  O  O   . VAL C 1 137 ? -77.002 -31.805 6.796   1.00 27.13  ? 116 VAL C O   1 
ATOM   7326  C  CB  . VAL C 1 137 ? -75.566 -34.795 6.486   1.00 26.29  ? 116 VAL C CB  1 
ATOM   7327  C  CG1 . VAL C 1 137 ? -75.410 -34.063 5.134   1.00 29.32  ? 116 VAL C CG1 1 
ATOM   7328  C  CG2 . VAL C 1 137 ? -74.276 -35.541 6.841   1.00 29.04  ? 116 VAL C CG2 1 
ATOM   7329  N  N   . ALA C 1 138 ? -78.344 -33.501 7.435   1.00 28.00  ? 117 ALA C N   1 
ATOM   7330  C  CA  . ALA C 1 138 ? -79.533 -32.700 7.161   1.00 26.87  ? 117 ALA C CA  1 
ATOM   7331  C  C   . ALA C 1 138 ? -79.653 -31.504 8.106   1.00 25.59  ? 117 ALA C C   1 
ATOM   7332  O  O   . ALA C 1 138 ? -80.253 -30.490 7.738   1.00 32.20  ? 117 ALA C O   1 
ATOM   7333  C  CB  . ALA C 1 138 ? -80.787 -33.570 7.253   1.00 31.32  ? 117 ALA C CB  1 
ATOM   7334  N  N   . GLU C 1 139 ? -79.131 -31.597 9.331   1.00 25.27  ? 118 GLU C N   1 
ATOM   7335  C  CA  . GLU C 1 139 ? -79.119 -30.401 10.184  1.00 23.52  ? 118 GLU C CA  1 
ATOM   7336  C  C   . GLU C 1 139 ? -78.154 -29.346 9.655   1.00 31.69  ? 118 GLU C C   1 
ATOM   7337  O  O   . GLU C 1 139 ? -78.383 -28.141 9.825   1.00 25.30  ? 118 GLU C O   1 
ATOM   7338  C  CB  . GLU C 1 139 ? -78.729 -30.752 11.624  1.00 31.48  ? 118 GLU C CB  1 
ATOM   7339  C  CG  . GLU C 1 139 ? -79.773 -31.555 12.388  1.00 32.36  ? 118 GLU C CG  1 
ATOM   7340  C  CD  . GLU C 1 139 ? -79.201 -32.218 13.639  1.00 56.23  ? 118 GLU C CD  1 
ATOM   7341  O  OE1 . GLU C 1 139 ? -78.054 -31.893 14.031  1.00 51.68  ? 118 GLU C OE1 1 
ATOM   7342  O  OE2 . GLU C 1 139 ? -79.901 -33.075 14.225  1.00 54.58  ? 118 GLU C OE2 1 
ATOM   7343  N  N   . PHE C 1 140 ? -77.062 -29.788 9.036   1.00 26.75  ? 119 PHE C N   1 
ATOM   7344  C  CA  . PHE C 1 140 ? -76.063 -28.859 8.520   1.00 24.06  ? 119 PHE C CA  1 
ATOM   7345  C  C   . PHE C 1 140 ? -76.563 -28.131 7.281   1.00 24.14  ? 119 PHE C C   1 
ATOM   7346  O  O   . PHE C 1 140 ? -76.316 -26.931 7.119   1.00 26.08  ? 119 PHE C O   1 
ATOM   7347  C  CB  . PHE C 1 140 ? -74.787 -29.651 8.222   1.00 23.59  ? 119 PHE C CB  1 
ATOM   7348  C  CG  . PHE C 1 140 ? -73.677 -28.821 7.618   1.00 25.28  ? 119 PHE C CG  1 
ATOM   7349  C  CD1 . PHE C 1 140 ? -72.915 -27.971 8.422   1.00 26.27  ? 119 PHE C CD1 1 
ATOM   7350  C  CD2 . PHE C 1 140 ? -73.390 -28.905 6.258   1.00 27.02  ? 119 PHE C CD2 1 
ATOM   7351  C  CE1 . PHE C 1 140 ? -71.866 -27.182 7.868   1.00 28.36  ? 119 PHE C CE1 1 
ATOM   7352  C  CE2 . PHE C 1 140 ? -72.347 -28.128 5.685   1.00 30.02  ? 119 PHE C CE2 1 
ATOM   7353  C  CZ  . PHE C 1 140 ? -71.592 -27.259 6.507   1.00 26.03  ? 119 PHE C CZ  1 
ATOM   7354  N  N   . ALA C 1 141 ? -77.295 -28.833 6.412   1.00 24.50  ? 120 ALA C N   1 
ATOM   7355  C  CA  . ALA C 1 141 ? -77.750 -28.280 5.136   1.00 27.53  ? 120 ALA C CA  1 
ATOM   7356  C  C   . ALA C 1 141 ? -78.408 -26.901 5.219   1.00 27.97  ? 120 ALA C C   1 
ATOM   7357  O  O   . ALA C 1 141 ? -77.969 -26.004 4.484   1.00 27.98  ? 120 ALA C O   1 
ATOM   7358  C  CB  . ALA C 1 141 ? -78.684 -29.295 4.456   1.00 28.37  ? 120 ALA C CB  1 
ATOM   7359  N  N   . PRO C 1 142 ? -79.457 -26.653 6.035   1.00 29.68  ? 121 PRO C N   1 
ATOM   7360  C  CA  . PRO C 1 142 ? -80.017 -25.290 6.058   1.00 33.04  ? 121 PRO C CA  1 
ATOM   7361  C  C   . PRO C 1 142 ? -79.072 -24.265 6.637   1.00 24.68  ? 121 PRO C C   1 
ATOM   7362  O  O   . PRO C 1 142 ? -79.142 -23.090 6.252   1.00 24.42  ? 121 PRO C O   1 
ATOM   7363  C  CB  . PRO C 1 142 ? -81.275 -25.421 6.930   1.00 31.54  ? 121 PRO C CB  1 
ATOM   7364  C  CG  . PRO C 1 142 ? -81.017 -26.582 7.776   1.00 33.26  ? 121 PRO C CG  1 
ATOM   7365  C  CD  . PRO C 1 142 ? -80.197 -27.543 6.952   1.00 30.10  ? 121 PRO C CD  1 
ATOM   7366  N  N   . LEU C 1 143 ? -78.201 -24.669 7.564   1.00 31.00  ? 122 LEU C N   1 
ATOM   7367  C  CA  . LEU C 1 143 ? -77.284 -23.720 8.185   1.00 29.17  ? 122 LEU C CA  1 
ATOM   7368  C  C   . LEU C 1 143 ? -76.246 -23.229 7.179   1.00 27.29  ? 122 LEU C C   1 
ATOM   7369  O  O   . LEU C 1 143 ? -76.006 -22.018 7.061   1.00 27.56  ? 122 LEU C O   1 
ATOM   7370  C  CB  . LEU C 1 143 ? -76.605 -24.365 9.393   1.00 24.56  ? 122 LEU C CB  1 
ATOM   7371  C  CG  . LEU C 1 143 ? -77.477 -24.825 10.565  1.00 28.56  ? 122 LEU C CG  1 
ATOM   7372  C  CD1 . LEU C 1 143 ? -76.715 -25.787 11.456  1.00 30.00  ? 122 LEU C CD1 1 
ATOM   7373  C  CD2 . LEU C 1 143 ? -77.928 -23.583 11.331  1.00 31.07  ? 122 LEU C CD2 1 
ATOM   7374  N  N   . VAL C 1 144 ? -75.644 -24.148 6.406   1.00 27.65  ? 123 VAL C N   1 
ATOM   7375  C  CA  . VAL C 1 144 ? -74.645 -23.677 5.444   1.00 29.43  ? 123 VAL C CA  1 
ATOM   7376  C  C   . VAL C 1 144 ? -75.314 -22.887 4.319   1.00 28.89  ? 123 VAL C C   1 
ATOM   7377  O  O   . VAL C 1 144 ? -74.765 -21.889 3.847   1.00 26.10  ? 123 VAL C O   1 
ATOM   7378  C  CB  . VAL C 1 144 ? -73.763 -24.835 4.905   1.00 24.90  ? 123 VAL C CB  1 
ATOM   7379  C  CG1 . VAL C 1 144 ? -74.532 -25.675 3.853   1.00 25.05  ? 123 VAL C CG1 1 
ATOM   7380  C  CG2 . VAL C 1 144 ? -72.517 -24.251 4.260   1.00 27.31  ? 123 VAL C CG2 1 
ATOM   7381  N  N   . ALA C 1 145 ? -76.543 -23.241 3.919   1.00 27.03  ? 124 ALA C N   1 
ATOM   7382  C  CA  . ALA C 1 145 ? -77.187 -22.432 2.886   1.00 26.56  ? 124 ALA C CA  1 
ATOM   7383  C  C   . ALA C 1 145 ? -77.431 -21.006 3.382   1.00 28.75  ? 124 ALA C C   1 
ATOM   7384  O  O   . ALA C 1 145 ? -77.232 -20.037 2.643   1.00 30.12  ? 124 ALA C O   1 
ATOM   7385  C  CB  . ALA C 1 145 ? -78.504 -23.081 2.444   1.00 28.14  ? 124 ALA C CB  1 
ATOM   7386  N  N   . GLU C 1 146 ? -77.845 -20.870 4.644   1.00 30.10  ? 125 GLU C N   1 
ATOM   7387  C  CA  . GLU C 1 146 ? -78.079 -19.555 5.238   1.00 28.22  ? 125 GLU C CA  1 
ATOM   7388  C  C   . GLU C 1 146 ? -76.800 -18.723 5.284   1.00 27.24  ? 125 GLU C C   1 
ATOM   7389  O  O   . GLU C 1 146 ? -76.815 -17.524 4.974   1.00 31.27  ? 125 GLU C O   1 
ATOM   7390  C  CB  . GLU C 1 146 ? -78.639 -19.751 6.646   1.00 31.11  ? 125 GLU C CB  1 
ATOM   7391  C  CG  . GLU C 1 146 ? -79.077 -18.513 7.347   1.00 47.81  ? 125 GLU C CG  1 
ATOM   7392  C  CD  . GLU C 1 146 ? -79.559 -18.813 8.771   1.00 58.53  ? 125 GLU C CD  1 
ATOM   7393  O  OE1 . GLU C 1 146 ? -79.714 -20.012 9.116   1.00 50.49  ? 125 GLU C OE1 1 
ATOM   7394  O  OE2 . GLU C 1 146 ? -79.773 -17.851 9.543   1.00 64.69  ? 125 GLU C OE2 1 
ATOM   7395  N  N   . GLU C 1 147 ? -75.689 -19.330 5.718   1.00 28.59  ? 126 GLU C N   1 
ATOM   7396  C  CA  . GLU C 1 147 ? -74.443 -18.573 5.852   1.00 25.69  ? 126 GLU C CA  1 
ATOM   7397  C  C   . GLU C 1 147 ? -73.855 -18.225 4.490   1.00 28.30  ? 126 GLU C C   1 
ATOM   7398  O  O   . GLU C 1 147 ? -73.256 -17.149 4.320   1.00 28.90  ? 126 GLU C O   1 
ATOM   7399  C  CB  . GLU C 1 147 ? -73.434 -19.377 6.671   1.00 23.93  ? 126 GLU C CB  1 
ATOM   7400  C  CG  . GLU C 1 147 ? -73.837 -19.630 8.111   1.00 26.77  ? 126 GLU C CG  1 
ATOM   7401  C  CD  . GLU C 1 147 ? -73.910 -18.359 8.951   1.00 34.60  ? 126 GLU C CD  1 
ATOM   7402  O  OE1 . GLU C 1 147 ? -73.506 -17.255 8.481   1.00 34.99  ? 126 GLU C OE1 1 
ATOM   7403  O  OE2 . GLU C 1 147 ? -74.375 -18.478 10.104  1.00 40.20  ? 126 GLU C OE2 1 
ATOM   7404  N  N   . VAL C 1 148 ? -74.023 -19.114 3.512   1.00 26.58  ? 127 VAL C N   1 
ATOM   7405  C  CA  . VAL C 1 148 ? -73.587 -18.796 2.161   1.00 26.20  ? 127 VAL C CA  1 
ATOM   7406  C  C   . VAL C 1 148 ? -74.396 -17.636 1.618   1.00 27.18  ? 127 VAL C C   1 
ATOM   7407  O  O   . VAL C 1 148 ? -73.846 -16.711 1.015   1.00 28.27  ? 127 VAL C O   1 
ATOM   7408  C  CB  . VAL C 1 148 ? -73.669 -20.036 1.251   1.00 24.28  ? 127 VAL C CB  1 
ATOM   7409  C  CG1 . VAL C 1 148 ? -73.519 -19.617 -0.201  1.00 25.15  ? 127 VAL C CG1 1 
ATOM   7410  C  CG2 . VAL C 1 148 ? -72.576 -21.002 1.618   1.00 26.10  ? 127 VAL C CG2 1 
ATOM   7411  N  N   . GLU C 1 149 ? -75.709 -17.636 1.869   1.00 31.03  ? 128 GLU C N   1 
ATOM   7412  C  CA  . GLU C 1 149 ? -76.533 -16.526 1.402   1.00 30.55  ? 128 GLU C CA  1 
ATOM   7413  C  C   . GLU C 1 149 ? -76.099 -15.206 2.026   1.00 27.80  ? 128 GLU C C   1 
ATOM   7414  O  O   . GLU C 1 149 ? -76.107 -14.170 1.360   1.00 33.89  ? 128 GLU C O   1 
ATOM   7415  C  CB  . GLU C 1 149 ? -78.016 -16.795 1.704   1.00 34.21  ? 128 GLU C CB  1 
ATOM   7416  C  CG  . GLU C 1 149 ? -78.647 -17.764 0.750   1.00 46.75  ? 128 GLU C CG  1 
ATOM   7417  C  CD  . GLU C 1 149 ? -78.450 -17.365 -0.711  1.00 70.26  ? 128 GLU C CD  1 
ATOM   7418  O  OE1 . GLU C 1 149 ? -78.510 -16.149 -1.011  1.00 74.95  ? 128 GLU C OE1 1 
ATOM   7419  O  OE2 . GLU C 1 149 ? -78.229 -18.267 -1.560  1.00 61.63  ? 128 GLU C OE2 1 
ATOM   7420  N  N   . ARG C 1 150 ? -75.698 -15.219 3.298   1.00 28.56  ? 129 ARG C N   1 
ATOM   7421  C  CA  . ARG C 1 150 ? -75.253 -13.978 3.929   1.00 33.66  ? 129 ARG C CA  1 
ATOM   7422  C  C   . ARG C 1 150 ? -73.952 -13.464 3.311   1.00 43.83  ? 129 ARG C C   1 
ATOM   7423  O  O   . ARG C 1 150 ? -73.798 -12.250 3.084   1.00 35.61  ? 129 ARG C O   1 
ATOM   7424  C  CB  . ARG C 1 150 ? -75.101 -14.188 5.437   1.00 36.81  ? 129 ARG C CB  1 
ATOM   7425  C  CG  . ARG C 1 150 ? -74.378 -13.063 6.138   1.00 53.91  ? 129 ARG C CG  1 
ATOM   7426  C  CD  . ARG C 1 150 ? -74.910 -12.802 7.554   1.00 61.04  ? 129 ARG C CD  1 
ATOM   7427  N  NE  . ARG C 1 150 ? -74.584 -13.878 8.481   1.00 52.19  ? 129 ARG C NE  1 
ATOM   7428  C  CZ  . ARG C 1 150 ? -73.735 -13.768 9.496   1.00 46.31  ? 129 ARG C CZ  1 
ATOM   7429  N  NH1 . ARG C 1 150 ? -73.142 -12.621 9.784   1.00 43.51  ? 129 ARG C NH1 1 
ATOM   7430  N  NH2 . ARG C 1 150 ? -73.476 -14.839 10.244  1.00 45.10  ? 129 ARG C NH2 1 
ATOM   7431  N  N   . ALA C 1 151 ? -72.999 -14.364 3.040   1.00 31.40  ? 130 ALA C N   1 
ATOM   7432  C  CA  . ALA C 1 151 ? -71.769 -13.961 2.348   1.00 25.91  ? 130 ALA C CA  1 
ATOM   7433  C  C   . ALA C 1 151 ? -72.070 -13.326 0.997   1.00 28.65  ? 130 ALA C C   1 
ATOM   7434  O  O   . ALA C 1 151 ? -71.549 -12.255 0.671   1.00 30.12  ? 130 ALA C O   1 
ATOM   7435  C  CB  . ALA C 1 151 ? -70.838 -15.167 2.167   1.00 28.10  ? 130 ALA C CB  1 
ATOM   7436  N  N   . VAL C 1 152 ? -72.913 -13.970 0.195   1.00 27.15  ? 131 VAL C N   1 
ATOM   7437  C  CA  . VAL C 1 152 ? -73.205 -13.452 -1.136  1.00 31.59  ? 131 VAL C CA  1 
ATOM   7438  C  C   . VAL C 1 152 ? -73.943 -12.119 -1.061  1.00 39.76  ? 131 VAL C C   1 
ATOM   7439  O  O   . VAL C 1 152 ? -73.664 -11.195 -1.843  1.00 32.10  ? 131 VAL C O   1 
ATOM   7440  C  CB  . VAL C 1 152 ? -73.982 -14.503 -1.940  1.00 36.53  ? 131 VAL C CB  1 
ATOM   7441  C  CG1 . VAL C 1 152 ? -74.517 -13.898 -3.209  1.00 46.22  ? 131 VAL C CG1 1 
ATOM   7442  C  CG2 . VAL C 1 152 ? -73.048 -15.670 -2.235  1.00 36.48  ? 131 VAL C CG2 1 
ATOM   7443  N  N   . ALA C 1 153 ? -74.883 -11.989 -0.116  1.00 39.03  ? 132 ALA C N   1 
ATOM   7444  C  CA  . ALA C 1 153 ? -75.526 -10.699 0.124   1.00 35.71  ? 132 ALA C CA  1 
ATOM   7445  C  C   . ALA C 1 153 ? -74.504 -9.603  0.399   1.00 33.59  ? 132 ALA C C   1 
ATOM   7446  O  O   . ALA C 1 153 ? -74.676 -8.467  -0.050  1.00 38.36  ? 132 ALA C O   1 
ATOM   7447  C  CB  . ALA C 1 153 ? -76.507 -10.798 1.294   1.00 41.61  ? 132 ALA C CB  1 
ATOM   7448  N  N   . GLY C 1 154 ? -73.432 -9.926  1.131   1.00 37.88  ? 133 GLY C N   1 
ATOM   7449  C  CA  . GLY C 1 154 ? -72.387 -8.977  1.462   1.00 36.35  ? 133 GLY C CA  1 
ATOM   7450  C  C   . GLY C 1 154 ? -71.561 -8.510  0.277   1.00 37.26  ? 133 GLY C C   1 
ATOM   7451  O  O   . GLY C 1 154 ? -70.823 -7.526  0.407   1.00 39.96  ? 133 GLY C O   1 
ATOM   7452  N  N   . TRP C 1 155 ? -71.671 -9.195  -0.862  1.00 32.12  ? 134 TRP C N   1 
ATOM   7453  C  CA  . TRP C 1 155 ? -70.982 -8.831  -2.092  1.00 37.66  ? 134 TRP C CA  1 
ATOM   7454  C  C   . TRP C 1 155 ? -71.706 -7.759  -2.898  1.00 33.36  ? 134 TRP C C   1 
ATOM   7455  O  O   . TRP C 1 155 ? -71.123 -7.229  -3.846  1.00 31.42  ? 134 TRP C O   1 
ATOM   7456  C  CB  . TRP C 1 155 ? -70.807 -10.073 -2.975  1.00 31.34  ? 134 TRP C CB  1 
ATOM   7457  C  CG  . TRP C 1 155 ? -69.935 -11.116 -2.348  1.00 26.29  ? 134 TRP C CG  1 
ATOM   7458  C  CD1 . TRP C 1 155 ? -69.102 -10.951 -1.281  1.00 29.15  ? 134 TRP C CD1 1 
ATOM   7459  C  CD2 . TRP C 1 155 ? -69.826 -12.488 -2.740  1.00 29.51  ? 134 TRP C CD2 1 
ATOM   7460  N  NE1 . TRP C 1 155 ? -68.457 -12.138 -0.992  1.00 30.68  ? 134 TRP C NE1 1 
ATOM   7461  C  CE2 . TRP C 1 155 ? -68.888 -13.096 -1.875  1.00 25.13  ? 134 TRP C CE2 1 
ATOM   7462  C  CE3 . TRP C 1 155 ? -70.402 -13.254 -3.755  1.00 24.36  ? 134 TRP C CE3 1 
ATOM   7463  C  CZ2 . TRP C 1 155 ? -68.547 -14.439 -1.976  1.00 27.66  ? 134 TRP C CZ2 1 
ATOM   7464  C  CZ3 . TRP C 1 155 ? -70.047 -14.588 -3.865  1.00 31.59  ? 134 TRP C CZ3 1 
ATOM   7465  C  CH2 . TRP C 1 155 ? -69.143 -15.170 -2.971  1.00 25.09  ? 134 TRP C CH2 1 
ATOM   7466  N  N   . GLU C 1 156 ? -72.963 -7.457  -2.588  1.00 35.36  ? 135 GLU C N   1 
ATOM   7467  C  CA  . GLU C 1 156 ? -73.721 -6.537  -3.432  1.00 36.25  ? 135 GLU C CA  1 
ATOM   7468  C  C   . GLU C 1 156 ? -73.068 -5.162  -3.414  1.00 39.48  ? 135 GLU C C   1 
ATOM   7469  O  O   . GLU C 1 156 ? -72.916 -4.549  -2.351  1.00 38.96  ? 135 GLU C O   1 
ATOM   7470  C  CB  . GLU C 1 156 ? -75.174 -6.443  -2.966  1.00 41.02  ? 135 GLU C CB  1 
ATOM   7471  C  CG  . GLU C 1 156 ? -75.909 -7.772  -2.969  1.00 72.76  ? 135 GLU C CG  1 
ATOM   7472  C  CD  . GLU C 1 156 ? -77.296 -7.684  -2.348  1.00 83.27  ? 135 GLU C CD  1 
ATOM   7473  O  OE1 . GLU C 1 156 ? -77.859 -6.564  -2.312  1.00 79.93  ? 135 GLU C OE1 1 
ATOM   7474  O  OE2 . GLU C 1 156 ? -77.810 -8.736  -1.893  1.00 73.31  ? 135 GLU C OE2 1 
ATOM   7475  N  N   . GLY C 1 157 ? -72.655 -4.697  -4.590  1.00 41.32  ? 136 GLY C N   1 
ATOM   7476  C  CA  . GLY C 1 157 ? -71.962 -3.423  -4.685  1.00 39.15  ? 136 GLY C CA  1 
ATOM   7477  C  C   . GLY C 1 157 ? -70.669 -3.345  -3.902  1.00 50.89  ? 136 GLY C C   1 
ATOM   7478  O  O   . GLY C 1 157 ? -70.254 -2.246  -3.519  1.00 50.35  ? 136 GLY C O   1 
ATOM   7479  N  N   . ALA C 1 158 ? -70.015 -4.482  -3.648  1.00 35.06  ? 137 ALA C N   1 
ATOM   7480  C  CA  . ALA C 1 158 ? -68.788 -4.512  -2.865  1.00 34.15  ? 137 ALA C CA  1 
ATOM   7481  C  C   . ALA C 1 158 ? -67.833 -5.534  -3.473  1.00 38.60  ? 137 ALA C C   1 
ATOM   7482  O  O   . ALA C 1 158 ? -68.208 -6.332  -4.336  1.00 35.93  ? 137 ALA C O   1 
ATOM   7483  C  CB  . ALA C 1 158 ? -69.063 -4.840  -1.396  1.00 35.89  ? 137 ALA C CB  1 
ATOM   7484  N  N   . GLN C 1 159 ? -66.585 -5.488  -3.032  1.00 31.31  ? 138 GLN C N   1 
ATOM   7485  C  CA  . GLN C 1 159 ? -65.553 -6.404  -3.521  1.00 42.58  ? 138 GLN C CA  1 
ATOM   7486  C  C   . GLN C 1 159 ? -65.495 -7.608  -2.588  1.00 33.28  ? 138 GLN C C   1 
ATOM   7487  O  O   . GLN C 1 159 ? -65.035 -7.490  -1.449  1.00 43.04  ? 138 GLN C O   1 
ATOM   7488  C  CB  . GLN C 1 159 ? -64.192 -5.709  -3.592  1.00 44.78  ? 138 GLN C CB  1 
ATOM   7489  C  CG  . GLN C 1 159 ? -64.208 -4.433  -4.422  1.00 65.76  ? 138 GLN C CG  1 
ATOM   7490  C  CD  . GLN C 1 159 ? -64.885 -4.631  -5.777  1.00 77.47  ? 138 GLN C CD  1 
ATOM   7491  O  OE1 . GLN C 1 159 ? -64.549 -5.558  -6.516  1.00 81.44  ? 138 GLN C OE1 1 
ATOM   7492  N  NE2 . GLN C 1 159 ? -65.851 -3.764  -6.100  1.00 61.85  ? 138 GLN C NE2 1 
ATOM   7493  N  N   . GLY C 1 160 ? -65.932 -8.773  -3.078  1.00 31.07  ? 139 GLY C N   1 
ATOM   7494  C  CA  . GLY C 1 160 ? -65.881 -9.994  -2.304  1.00 26.11  ? 139 GLY C CA  1 
ATOM   7495  C  C   . GLY C 1 160 ? -64.708 -10.897 -2.695  1.00 25.10  ? 139 GLY C C   1 
ATOM   7496  O  O   . GLY C 1 160 ? -63.973 -10.654 -3.638  1.00 28.33  ? 139 GLY C O   1 
ATOM   7497  N  N   . ASN C 1 161 ? -64.555 -11.966 -1.931  1.00 30.07  ? 140 ASN C N   1 
ATOM   7498  C  CA  . ASN C 1 161 ? -63.454 -12.910 -2.110  1.00 25.80  ? 140 ASN C CA  1 
ATOM   7499  C  C   . ASN C 1 161 ? -64.028 -14.293 -1.842  1.00 27.67  ? 140 ASN C C   1 
ATOM   7500  O  O   . ASN C 1 161 ? -64.429 -14.573 -0.707  1.00 23.31  ? 140 ASN C O   1 
ATOM   7501  C  CB  . ASN C 1 161 ? -62.323 -12.603 -1.125  1.00 27.36  ? 140 ASN C CB  1 
ATOM   7502  C  CG  . ASN C 1 161 ? -61.088 -13.402 -1.403  1.00 27.51  ? 140 ASN C CG  1 
ATOM   7503  O  OD1 . ASN C 1 161 ? -60.970 -14.554 -0.977  1.00 25.89  ? 140 ASN C OD1 1 
ATOM   7504  N  ND2 . ASN C 1 161 ? -60.142 -12.791 -2.118  1.00 33.63  ? 140 ASN C ND2 1 
ATOM   7505  N  N   . VAL C 1 162 ? -64.062 -15.156 -2.863  1.00 23.31  ? 141 VAL C N   1 
ATOM   7506  C  CA  . VAL C 1 162 ? -64.696 -16.461 -2.696  1.00 24.15  ? 141 VAL C CA  1 
ATOM   7507  C  C   . VAL C 1 162 ? -64.007 -17.258 -1.595  1.00 23.93  ? 141 VAL C C   1 
ATOM   7508  O  O   . VAL C 1 162 ? -64.654 -17.746 -0.660  1.00 21.54  ? 141 VAL C O   1 
ATOM   7509  C  CB  . VAL C 1 162 ? -64.701 -17.234 -4.023  1.00 23.68  ? 141 VAL C CB  1 
ATOM   7510  C  CG1 . VAL C 1 162 ? -65.400 -18.614 -3.830  1.00 23.33  ? 141 VAL C CG1 1 
ATOM   7511  C  CG2 . VAL C 1 162 ? -65.403 -16.434 -5.125  1.00 24.25  ? 141 VAL C CG2 1 
ATOM   7512  N  N   . PHE C 1 163 ? -62.674 -17.370 -1.661  1.00 21.75  ? 142 PHE C N   1 
ATOM   7513  C  CA  . PHE C 1 163 ? -61.950 -18.132 -0.636  1.00 22.76  ? 142 PHE C CA  1 
ATOM   7514  C  C   . PHE C 1 163 ? -62.215 -17.599 0.776   1.00 25.57  ? 142 PHE C C   1 
ATOM   7515  O  O   . PHE C 1 163 ? -62.631 -18.355 1.670   1.00 24.37  ? 142 PHE C O   1 
ATOM   7516  C  CB  . PHE C 1 163 ? -60.434 -18.147 -0.913  1.00 21.57  ? 142 PHE C CB  1 
ATOM   7517  C  CG  . PHE C 1 163 ? -59.658 -18.904 0.132   1.00 23.65  ? 142 PHE C CG  1 
ATOM   7518  C  CD1 . PHE C 1 163 ? -59.788 -20.274 0.241   1.00 26.25  ? 142 PHE C CD1 1 
ATOM   7519  C  CD2 . PHE C 1 163 ? -58.838 -18.232 1.037   1.00 23.85  ? 142 PHE C CD2 1 
ATOM   7520  C  CE1 . PHE C 1 163 ? -59.097 -21.006 1.226   1.00 22.48  ? 142 PHE C CE1 1 
ATOM   7521  C  CE2 . PHE C 1 163 ? -58.145 -18.927 2.027   1.00 22.07  ? 142 PHE C CE2 1 
ATOM   7522  C  CZ  . PHE C 1 163 ? -58.272 -20.310 2.138   1.00 25.03  ? 142 PHE C CZ  1 
ATOM   7523  N  N   . GLU C 1 164 ? -61.949 -16.309 1.012   1.00 23.34  ? 143 GLU C N   1 
ATOM   7524  C  CA  . GLU C 1 164 ? -62.048 -15.790 2.379   1.00 27.82  ? 143 GLU C CA  1 
ATOM   7525  C  C   . GLU C 1 164 ? -63.490 -15.822 2.886   1.00 23.49  ? 143 GLU C C   1 
ATOM   7526  O  O   . GLU C 1 164 ? -63.752 -16.232 4.022   1.00 26.53  ? 143 GLU C O   1 
ATOM   7527  C  CB  . GLU C 1 164 ? -61.503 -14.354 2.459   1.00 25.22  ? 143 GLU C CB  1 
ATOM   7528  C  CG  . GLU C 1 164 ? -60.002 -14.247 2.189   1.00 49.96  ? 143 GLU C CG  1 
ATOM   7529  C  CD  . GLU C 1 164 ? -59.116 -14.939 3.245   1.00 61.01  ? 143 GLU C CD  1 
ATOM   7530  O  OE1 . GLU C 1 164 ? -59.585 -15.170 4.391   1.00 49.86  ? 143 GLU C OE1 1 
ATOM   7531  O  OE2 . GLU C 1 164 ? -57.937 -15.241 2.919   1.00 47.76  ? 143 GLU C OE2 1 
ATOM   7532  N  N   . ASP C 1 165 ? -64.429 -15.391 2.049   1.00 21.58  ? 144 ASP C N   1 
ATOM   7533  C  CA  . ASP C 1 165 ? -65.791 -15.135 2.508   1.00 24.20  ? 144 ASP C CA  1 
ATOM   7534  C  C   . ASP C 1 165 ? -66.585 -16.431 2.615   1.00 25.14  ? 144 ASP C C   1 
ATOM   7535  O  O   . ASP C 1 165 ? -67.399 -16.587 3.539   1.00 25.37  ? 144 ASP C O   1 
ATOM   7536  C  CB  . ASP C 1 165 ? -66.502 -14.148 1.569   1.00 27.82  ? 144 ASP C CB  1 
ATOM   7537  C  CG  . ASP C 1 165 ? -65.817 -12.763 1.506   1.00 35.94  ? 144 ASP C CG  1 
ATOM   7538  O  OD1 . ASP C 1 165 ? -64.969 -12.468 2.361   1.00 29.34  ? 144 ASP C OD1 1 
ATOM   7539  O  OD2 . ASP C 1 165 ? -66.131 -11.972 0.584   1.00 27.58  ? 144 ASP C OD2 1 
ATOM   7540  N  N   . LEU C 1 166 ? -66.376 -17.372 1.686   1.00 23.17  ? 145 LEU C N   1 
ATOM   7541  C  CA  . LEU C 1 166 ? -67.063 -18.659 1.811   1.00 21.34  ? 145 LEU C CA  1 
ATOM   7542  C  C   . LEU C 1 166 ? -66.409 -19.574 2.841   1.00 27.56  ? 145 LEU C C   1 
ATOM   7543  O  O   . LEU C 1 166 ? -67.126 -20.347 3.490   1.00 25.23  ? 145 LEU C O   1 
ATOM   7544  C  CB  . LEU C 1 166 ? -67.178 -19.372 0.446   1.00 22.15  ? 145 LEU C CB  1 
ATOM   7545  C  CG  . LEU C 1 166 ? -68.091 -18.625 -0.558  1.00 27.18  ? 145 LEU C CG  1 
ATOM   7546  C  CD1 . LEU C 1 166 ? -68.507 -19.498 -1.711  1.00 23.33  ? 145 LEU C CD1 1 
ATOM   7547  C  CD2 . LEU C 1 166 ? -69.315 -17.977 0.107   1.00 32.07  ? 145 LEU C CD2 1 
ATOM   7548  N  N   . SER C 1 167 ? -65.078 -19.515 3.043   1.00 22.29  ? 146 SER C N   1 
ATOM   7549  C  CA  . SER C 1 167 ? -64.521 -20.249 4.183   1.00 20.81  ? 146 SER C CA  1 
ATOM   7550  C  C   . SER C 1 167 ? -65.129 -19.751 5.496   1.00 23.17  ? 146 SER C C   1 
ATOM   7551  O  O   . SER C 1 167 ? -65.445 -20.548 6.397   1.00 26.43  ? 146 SER C O   1 
ATOM   7552  C  CB  . SER C 1 167 ? -62.990 -20.122 4.240   1.00 21.28  ? 146 SER C CB  1 
ATOM   7553  O  OG  . SER C 1 167 ? -62.368 -20.651 3.071   1.00 24.75  ? 146 SER C OG  1 
ATOM   7554  N  N   . LEU C 1 168 ? -65.287 -18.437 5.627   1.00 23.54  ? 147 LEU C N   1 
ATOM   7555  C  CA  . LEU C 1 168 ? -65.912 -17.889 6.832   1.00 24.14  ? 147 LEU C CA  1 
ATOM   7556  C  C   . LEU C 1 168 ? -67.367 -18.358 6.955   1.00 21.25  ? 147 LEU C C   1 
ATOM   7557  O  O   . LEU C 1 168 ? -67.790 -18.791 8.026   1.00 26.15  ? 147 LEU C O   1 
ATOM   7558  C  CB  . LEU C 1 168 ? -65.827 -16.364 6.802   1.00 24.90  ? 147 LEU C CB  1 
ATOM   7559  C  CG  . LEU C 1 168 ? -66.467 -15.678 8.024   1.00 29.20  ? 147 LEU C CG  1 
ATOM   7560  C  CD1 . LEU C 1 168 ? -65.752 -16.094 9.286   1.00 30.35  ? 147 LEU C CD1 1 
ATOM   7561  C  CD2 . LEU C 1 168 ? -66.370 -14.167 7.873   1.00 31.44  ? 147 LEU C CD2 1 
ATOM   7562  N  N   . ALA C 1 169 ? -68.121 -18.325 5.854   1.00 23.81  ? 148 ALA C N   1 
ATOM   7563  C  CA  . ALA C 1 169 ? -69.495 -18.842 5.847   1.00 25.75  ? 148 ALA C CA  1 
ATOM   7564  C  C   . ALA C 1 169 ? -69.541 -20.306 6.273   1.00 27.05  ? 148 ALA C C   1 
ATOM   7565  O  O   . ALA C 1 169 ? -70.389 -20.703 7.082   1.00 26.25  ? 148 ALA C O   1 
ATOM   7566  C  CB  . ALA C 1 169 ? -70.120 -18.668 4.453   1.00 23.93  ? 148 ALA C CB  1 
ATOM   7567  N  N   . PHE C 1 170 ? -68.616 -21.124 5.755   1.00 21.42  ? 149 PHE C N   1 
ATOM   7568  C  CA  . PHE C 1 170 ? -68.582 -22.527 6.145   1.00 26.22  ? 149 PHE C CA  1 
ATOM   7569  C  C   . PHE C 1 170 ? -68.257 -22.695 7.626   1.00 29.42  ? 149 PHE C C   1 
ATOM   7570  O  O   . PHE C 1 170 ? -68.836 -23.557 8.298   1.00 25.89  ? 149 PHE C O   1 
ATOM   7571  C  CB  . PHE C 1 170 ? -67.565 -23.294 5.288   1.00 23.41  ? 149 PHE C CB  1 
ATOM   7572  C  CG  . PHE C 1 170 ? -67.920 -23.372 3.807   1.00 25.02  ? 149 PHE C CG  1 
ATOM   7573  C  CD1 . PHE C 1 170 ? -69.231 -23.206 3.364   1.00 19.39  ? 149 PHE C CD1 1 
ATOM   7574  C  CD2 . PHE C 1 170 ? -66.922 -23.616 2.860   1.00 28.94  ? 149 PHE C CD2 1 
ATOM   7575  C  CE1 . PHE C 1 170 ? -69.550 -23.250 2.002   1.00 22.82  ? 149 PHE C CE1 1 
ATOM   7576  C  CE2 . PHE C 1 170 ? -67.232 -23.679 1.504   1.00 24.39  ? 149 PHE C CE2 1 
ATOM   7577  C  CZ  . PHE C 1 170 ? -68.561 -23.503 1.072   1.00 29.43  ? 149 PHE C CZ  1 
ATOM   7578  N  N   . GLY C 1 171 ? -67.320 -21.899 8.157   1.00 25.22  ? 150 GLY C N   1 
ATOM   7579  C  CA  . GLY C 1 171 ? -66.991 -22.025 9.566   1.00 26.75  ? 150 GLY C CA  1 
ATOM   7580  C  C   . GLY C 1 171 ? -68.128 -21.597 10.483  1.00 26.17  ? 150 GLY C C   1 
ATOM   7581  O  O   . GLY C 1 171 ? -68.387 -22.244 11.501  1.00 27.09  ? 150 GLY C O   1 
ATOM   7582  N  N   . ARG C 1 172 ? -68.809 -20.500 10.140  1.00 24.34  ? 151 ARG C N   1 
ATOM   7583  C  CA  . ARG C 1 172 ? -69.988 -20.087 10.901  1.00 27.76  ? 151 ARG C CA  1 
ATOM   7584  C  C   . ARG C 1 172 ? -71.021 -21.203 10.942  1.00 27.12  ? 151 ARG C C   1 
ATOM   7585  O  O   . ARG C 1 172 ? -71.580 -21.524 11.999  1.00 25.59  ? 151 ARG C O   1 
ATOM   7586  C  CB  . ARG C 1 172 ? -70.598 -18.841 10.274  1.00 25.76  ? 151 ARG C CB  1 
ATOM   7587  C  CG  . ARG C 1 172 ? -69.773 -17.588 10.512  1.00 30.05  ? 151 ARG C CG  1 
ATOM   7588  C  CD  . ARG C 1 172 ? -70.289 -16.465 9.630   1.00 29.31  ? 151 ARG C CD  1 
ATOM   7589  N  NE  . ARG C 1 172 ? -69.653 -15.193 9.971   1.00 36.51  ? 151 ARG C NE  1 
ATOM   7590  C  CZ  . ARG C 1 172 ? -69.834 -14.060 9.307   1.00 40.68  ? 151 ARG C CZ  1 
ATOM   7591  N  NH1 . ARG C 1 172 ? -70.560 -14.014 8.200   1.00 36.03  ? 151 ARG C NH1 1 
ATOM   7592  N  NH2 . ARG C 1 172 ? -69.287 -12.939 9.774   1.00 35.45  ? 151 ARG C NH2 1 
ATOM   7593  N  N   . ALA C 1 173 ? -71.283 -21.813 9.787   1.00 24.63  ? 152 ALA C N   1 
ATOM   7594  C  CA  . ALA C 1 173 ? -72.240 -22.910 9.738   1.00 22.86  ? 152 ALA C CA  1 
ATOM   7595  C  C   . ALA C 1 173 ? -71.757 -24.096 10.556  1.00 26.96  ? 152 ALA C C   1 
ATOM   7596  O  O   . ALA C 1 173 ? -72.538 -24.696 11.294  1.00 25.44  ? 152 ALA C O   1 
ATOM   7597  C  CB  . ALA C 1 173 ? -72.491 -23.319 8.281   1.00 22.72  ? 152 ALA C CB  1 
ATOM   7598  N  N   . ALA C 1 174 ? -70.466 -24.444 10.449  1.00 23.89  ? 153 ALA C N   1 
ATOM   7599  C  CA  . ALA C 1 174 ? -69.932 -25.558 11.226  1.00 24.74  ? 153 ALA C CA  1 
ATOM   7600  C  C   . ALA C 1 174 ? -70.085 -25.335 12.735  1.00 28.12  ? 153 ALA C C   1 
ATOM   7601  O  O   . ALA C 1 174 ? -70.433 -26.270 13.480  1.00 25.95  ? 153 ALA C O   1 
ATOM   7602  C  CB  . ALA C 1 174 ? -68.450 -25.795 10.865  1.00 24.23  ? 153 ALA C CB  1 
ATOM   7603  N  N   . PHE C 1 175 ? -69.777 -24.130 13.218  1.00 28.50  ? 154 PHE C N   1 
ATOM   7604  C  CA  . PHE C 1 175 ? -69.856 -23.890 14.665  1.00 28.93  ? 154 PHE C CA  1 
ATOM   7605  C  C   . PHE C 1 175 ? -71.294 -24.016 15.162  1.00 30.04  ? 154 PHE C C   1 
ATOM   7606  O  O   . PHE C 1 175 ? -71.559 -24.638 16.205  1.00 30.79  ? 154 PHE C O   1 
ATOM   7607  C  CB  . PHE C 1 175 ? -69.305 -22.503 15.005  1.00 30.95  ? 154 PHE C CB  1 
ATOM   7608  C  CG  . PHE C 1 175 ? -67.817 -22.485 15.266  1.00 30.82  ? 154 PHE C CG  1 
ATOM   7609  C  CD1 . PHE C 1 175 ? -66.947 -23.141 14.410  1.00 31.08  ? 154 PHE C CD1 1 
ATOM   7610  C  CD2 . PHE C 1 175 ? -67.295 -21.795 16.359  1.00 31.56  ? 154 PHE C CD2 1 
ATOM   7611  C  CE1 . PHE C 1 175 ? -65.563 -23.134 14.641  1.00 34.32  ? 154 PHE C CE1 1 
ATOM   7612  C  CE2 . PHE C 1 175 ? -65.930 -21.769 16.603  1.00 32.59  ? 154 PHE C CE2 1 
ATOM   7613  C  CZ  . PHE C 1 175 ? -65.056 -22.431 15.751  1.00 38.24  ? 154 PHE C CZ  1 
ATOM   7614  N  N   . ARG C 1 176 ? -72.223 -23.392 14.439  1.00 26.61  ? 155 ARG C N   1 
ATOM   7615  C  CA  . ARG C 1 176 ? -73.640 -23.496 14.776  1.00 32.45  ? 155 ARG C CA  1 
ATOM   7616  C  C   . ARG C 1 176 ? -74.098 -24.941 14.744  1.00 32.44  ? 155 ARG C C   1 
ATOM   7617  O  O   . ARG C 1 176 ? -74.764 -25.418 15.672  1.00 29.22  ? 155 ARG C O   1 
ATOM   7618  C  CB  . ARG C 1 176 ? -74.466 -22.658 13.809  1.00 31.66  ? 155 ARG C CB  1 
ATOM   7619  C  CG  . ARG C 1 176 ? -74.241 -21.167 13.978  1.00 31.40  ? 155 ARG C CG  1 
ATOM   7620  C  CD  . ARG C 1 176 ? -75.005 -20.381 12.927  1.00 36.38  ? 155 ARG C CD  1 
ATOM   7621  N  NE  . ARG C 1 176 ? -76.448 -20.584 13.047  1.00 37.86  ? 155 ARG C NE  1 
ATOM   7622  C  CZ  . ARG C 1 176 ? -77.331 -20.258 12.110  1.00 42.24  ? 155 ARG C CZ  1 
ATOM   7623  N  NH1 . ARG C 1 176 ? -76.949 -19.790 10.925  1.00 35.38  ? 155 ARG C NH1 1 
ATOM   7624  N  NH2 . ARG C 1 176 ? -78.630 -20.425 12.355  1.00 41.84  ? 155 ARG C NH2 1 
ATOM   7625  N  N   . TRP C 1 177 ? -73.744 -25.655 13.672  1.00 28.43  ? 156 TRP C N   1 
ATOM   7626  C  CA  . TRP C 1 177 ? -74.097 -27.062 13.543  1.00 28.81  ? 156 TRP C CA  1 
ATOM   7627  C  C   . TRP C 1 177 ? -73.577 -27.888 14.721  1.00 37.35  ? 156 TRP C C   1 
ATOM   7628  O  O   . TRP C 1 177 ? -74.286 -28.761 15.237  1.00 31.19  ? 156 TRP C O   1 
ATOM   7629  C  CB  . TRP C 1 177 ? -73.537 -27.597 12.213  1.00 25.47  ? 156 TRP C CB  1 
ATOM   7630  C  CG  . TRP C 1 177 ? -73.633 -29.073 12.064  1.00 25.23  ? 156 TRP C CG  1 
ATOM   7631  C  CD1 . TRP C 1 177 ? -74.773 -29.801 11.803  1.00 25.36  ? 156 TRP C CD1 1 
ATOM   7632  C  CD2 . TRP C 1 177 ? -72.565 -30.013 12.163  1.00 25.42  ? 156 TRP C CD2 1 
ATOM   7633  N  NE1 . TRP C 1 177 ? -74.469 -31.140 11.732  1.00 29.13  ? 156 TRP C NE1 1 
ATOM   7634  C  CE2 . TRP C 1 177 ? -73.120 -31.298 11.953  1.00 25.42  ? 156 TRP C CE2 1 
ATOM   7635  C  CE3 . TRP C 1 177 ? -71.181 -29.896 12.406  1.00 24.38  ? 156 TRP C CE3 1 
ATOM   7636  C  CZ2 . TRP C 1 177 ? -72.350 -32.457 11.988  1.00 25.54  ? 156 TRP C CZ2 1 
ATOM   7637  C  CZ3 . TRP C 1 177 ? -70.419 -31.044 12.443  1.00 30.97  ? 156 TRP C CZ3 1 
ATOM   7638  C  CH2 . TRP C 1 177 ? -71.001 -32.318 12.236  1.00 26.04  ? 156 TRP C CH2 1 
ATOM   7639  N  N   . ALA C 1 178 ? -72.328 -27.653 15.143  1.00 27.45  ? 157 ALA C N   1 
ATOM   7640  C  CA  . ALA C 1 178 ? -71.729 -28.455 16.207  1.00 28.30  ? 157 ALA C CA  1 
ATOM   7641  C  C   . ALA C 1 178 ? -72.227 -28.102 17.599  1.00 27.96  ? 157 ALA C C   1 
ATOM   7642  O  O   . ALA C 1 178 ? -71.890 -28.815 18.548  1.00 31.10  ? 157 ALA C O   1 
ATOM   7643  C  CB  . ALA C 1 178 ? -70.212 -28.288 16.210  1.00 29.17  ? 157 ALA C CB  1 
ATOM   7644  N  N   . GLY C 1 179 ? -72.992 -27.019 17.749  1.00 32.22  ? 158 GLY C N   1 
ATOM   7645  C  CA  . GLY C 1 179 ? -73.424 -26.580 19.068  1.00 35.47  ? 158 GLY C CA  1 
ATOM   7646  C  C   . GLY C 1 179 ? -72.417 -25.752 19.842  1.00 36.28  ? 158 GLY C C   1 
ATOM   7647  O  O   . GLY C 1 179 ? -72.530 -25.645 21.067  1.00 36.78  ? 158 GLY C O   1 
ATOM   7648  N  N   . ILE C 1 180 ? -71.420 -25.180 19.167  1.00 33.22  ? 159 ILE C N   1 
ATOM   7649  C  CA  . ILE C 1 180 ? -70.472 -24.225 19.757  1.00 34.08  ? 159 ILE C CA  1 
ATOM   7650  C  C   . ILE C 1 180 ? -71.162 -22.866 19.750  1.00 35.78  ? 159 ILE C C   1 
ATOM   7651  O  O   . ILE C 1 180 ? -71.171 -22.174 18.735  1.00 45.51  ? 159 ILE C O   1 
ATOM   7652  C  CB  . ILE C 1 180 ? -69.153 -24.174 18.978  1.00 35.96  ? 159 ILE C CB  1 
ATOM   7653  C  CG1 . ILE C 1 180 ? -68.562 -25.572 18.810  1.00 35.75  ? 159 ILE C CG1 1 
ATOM   7654  C  CG2 . ILE C 1 180 ? -68.138 -23.243 19.650  1.00 32.05  ? 159 ILE C CG2 1 
ATOM   7655  C  CD1 . ILE C 1 180 ? -67.326 -25.570 17.941  1.00 29.48  ? 159 ILE C CD1 1 
ATOM   7656  N  N   . ASP C 1 181 ? -71.736 -22.470 20.875  1.00 38.07  ? 160 ASP C N   1 
ATOM   7657  C  CA  . ASP C 1 181 ? -72.499 -21.229 20.959  1.00 32.43  ? 160 ASP C CA  1 
ATOM   7658  C  C   . ASP C 1 181 ? -71.607 -20.136 21.552  1.00 48.57  ? 160 ASP C C   1 
ATOM   7659  O  O   . ASP C 1 181 ? -71.325 -20.139 22.755  1.00 44.86  ? 160 ASP C O   1 
ATOM   7660  C  CB  . ASP C 1 181 ? -73.754 -21.435 21.803  1.00 50.41  ? 160 ASP C CB  1 
ATOM   7661  C  CG  . ASP C 1 181 ? -74.716 -20.254 21.727  1.00 74.71  ? 160 ASP C CG  1 
ATOM   7662  O  OD1 . ASP C 1 181 ? -74.498 -19.351 20.885  1.00 75.39  ? 160 ASP C OD1 1 
ATOM   7663  O  OD2 . ASP C 1 181 ? -75.694 -20.232 22.510  1.00 85.75  ? 160 ASP C OD2 1 
ATOM   7664  N  N   . LEU C 1 182 ? -71.161 -19.212 20.715  1.00 42.71  ? 161 LEU C N   1 
ATOM   7665  C  CA  . LEU C 1 182 ? -70.299 -18.114 21.119  1.00 41.24  ? 161 LEU C CA  1 
ATOM   7666  C  C   . LEU C 1 182 ? -70.815 -16.830 20.491  1.00 39.03  ? 161 LEU C C   1 
ATOM   7667  O  O   . LEU C 1 182 ? -71.585 -16.872 19.524  1.00 40.15  ? 161 LEU C O   1 
ATOM   7668  C  CB  . LEU C 1 182 ? -68.845 -18.362 20.684  1.00 35.09  ? 161 LEU C CB  1 
ATOM   7669  C  CG  . LEU C 1 182 ? -68.124 -19.635 21.128  1.00 45.79  ? 161 LEU C CG  1 
ATOM   7670  C  CD1 . LEU C 1 182 ? -66.787 -19.789 20.375  1.00 39.38  ? 161 LEU C CD1 1 
ATOM   7671  C  CD2 . LEU C 1 182 ? -67.894 -19.649 22.628  1.00 43.27  ? 161 LEU C CD2 1 
ATOM   7672  N  N   . PRO C 1 183 ? -70.410 -15.666 21.010  1.00 39.19  ? 162 PRO C N   1 
ATOM   7673  C  CA  . PRO C 1 183 ? -70.750 -14.406 20.334  1.00 34.55  ? 162 PRO C CA  1 
ATOM   7674  C  C   . PRO C 1 183 ? -70.204 -14.382 18.909  1.00 48.06  ? 162 PRO C C   1 
ATOM   7675  O  O   . PRO C 1 183 ? -69.242 -15.075 18.570  1.00 40.10  ? 162 PRO C O   1 
ATOM   7676  C  CB  . PRO C 1 183 ? -70.086 -13.332 21.210  1.00 39.54  ? 162 PRO C CB  1 
ATOM   7677  C  CG  . PRO C 1 183 ? -69.962 -13.947 22.541  1.00 41.38  ? 162 PRO C CG  1 
ATOM   7678  C  CD  . PRO C 1 183 ? -69.745 -15.434 22.308  1.00 38.01  ? 162 PRO C CD  1 
ATOM   7679  N  N   . ALA C 1 184 ? -70.843 -13.564 18.070  1.00 34.86  ? 163 ALA C N   1 
ATOM   7680  C  CA  . ALA C 1 184 ? -70.508 -13.528 16.648  1.00 43.08  ? 163 ALA C CA  1 
ATOM   7681  C  C   . ALA C 1 184 ? -69.030 -13.241 16.431  1.00 46.90  ? 163 ALA C C   1 
ATOM   7682  O  O   . ALA C 1 184 ? -68.359 -13.926 15.646  1.00 40.69  ? 163 ALA C O   1 
ATOM   7683  C  CB  . ALA C 1 184 ? -71.354 -12.475 15.941  1.00 43.65  ? 163 ALA C CB  1 
ATOM   7684  N  N   . GLU C 1 185 ? -68.500 -12.235 17.131  1.00 39.78  ? 164 GLU C N   1 
ATOM   7685  C  CA  . GLU C 1 185 ? -67.116 -11.831 16.914  1.00 40.50  ? 164 GLU C CA  1 
ATOM   7686  C  C   . GLU C 1 185 ? -66.155 -12.938 17.313  1.00 40.52  ? 164 GLU C C   1 
ATOM   7687  O  O   . GLU C 1 185 ? -65.128 -13.145 16.649  1.00 36.31  ? 164 GLU C O   1 
ATOM   7688  C  CB  . GLU C 1 185 ? -66.809 -10.543 17.689  1.00 43.96  ? 164 GLU C CB  1 
ATOM   7689  C  CG  . GLU C 1 185 ? -65.382 -10.031 17.483  1.00 69.79  ? 164 GLU C CG  1 
ATOM   7690  C  CD  . GLU C 1 185 ? -64.932 -9.029  18.548  1.00 95.28  ? 164 GLU C CD  1 
ATOM   7691  O  OE1 . GLU C 1 185 ? -65.398 -9.126  19.705  1.00 94.10  ? 164 GLU C OE1 1 
ATOM   7692  O  OE2 . GLU C 1 185 ? -64.106 -8.145  18.226  1.00 95.11  ? 164 GLU C OE2 1 
ATOM   7693  N  N   . ASN C 1 186 ? -66.463 -13.657 18.402  1.00 35.86  ? 165 ASN C N   1 
ATOM   7694  C  CA  . ASN C 1 186 ? -65.582 -14.732 18.845  1.00 36.19  ? 165 ASN C CA  1 
ATOM   7695  C  C   . ASN C 1 186 ? -65.548 -15.852 17.819  1.00 41.75  ? 165 ASN C C   1 
ATOM   7696  O  O   . ASN C 1 186 ? -64.489 -16.426 17.549  1.00 31.37  ? 165 ASN C O   1 
ATOM   7697  C  CB  . ASN C 1 186 ? -66.037 -15.314 20.182  1.00 37.89  ? 165 ASN C CB  1 
ATOM   7698  C  CG  . ASN C 1 186 ? -66.031 -14.292 21.311  1.00 58.48  ? 165 ASN C CG  1 
ATOM   7699  O  OD1 . ASN C 1 186 ? -66.488 -13.147 21.155  1.00 49.52  ? 165 ASN C OD1 1 
ATOM   7700  N  ND2 . ASN C 1 186 ? -65.509 -14.707 22.461  1.00 57.48  ? 165 ASN C ND2 1 
ATOM   7701  N  N   . THR C 1 187 ? -66.717 -16.200 17.279  1.00 31.68  ? 166 THR C N   1 
ATOM   7702  C  CA  . THR C 1 187 ? -66.803 -17.234 16.256  1.00 39.37  ? 166 THR C CA  1 
ATOM   7703  C  C   . THR C 1 187 ? -66.006 -16.846 15.019  1.00 27.93  ? 166 THR C C   1 
ATOM   7704  O  O   . THR C 1 187 ? -65.206 -17.644 14.518  1.00 30.15  ? 166 THR C O   1 
ATOM   7705  C  CB  . THR C 1 187 ? -68.271 -17.492 15.930  1.00 34.86  ? 166 THR C CB  1 
ATOM   7706  O  OG1 . THR C 1 187 ? -68.884 -18.053 17.099  1.00 37.18  ? 166 THR C OG1 1 
ATOM   7707  C  CG2 . THR C 1 187 ? -68.431 -18.468 14.758  1.00 35.53  ? 166 THR C CG2 1 
ATOM   7708  N  N   . ASP C 1 188 ? -66.192 -15.619 14.530  1.00 30.13  ? 167 ASP C N   1 
ATOM   7709  C  CA  . ASP C 1 188 ? -65.453 -15.176 13.353  1.00 34.24  ? 167 ASP C CA  1 
ATOM   7710  C  C   . ASP C 1 188 ? -63.946 -15.205 13.600  1.00 39.53  ? 167 ASP C C   1 
ATOM   7711  O  O   . ASP C 1 188 ? -63.165 -15.548 12.695  1.00 30.99  ? 167 ASP C O   1 
ATOM   7712  C  CB  . ASP C 1 188 ? -65.903 -13.774 12.928  1.00 30.42  ? 167 ASP C CB  1 
ATOM   7713  C  CG  . ASP C 1 188 ? -67.295 -13.773 12.264  1.00 38.99  ? 167 ASP C CG  1 
ATOM   7714  O  OD1 . ASP C 1 188 ? -67.919 -14.842 12.150  1.00 40.27  ? 167 ASP C OD1 1 
ATOM   7715  O  OD2 . ASP C 1 188 ? -67.775 -12.697 11.850  1.00 45.33  ? 167 ASP C OD2 1 
ATOM   7716  N  N   . GLU C 1 189 ? -63.517 -14.874 14.822  1.00 29.78  ? 168 GLU C N   1 
ATOM   7717  C  CA  . GLU C 1 189 ? -62.085 -14.869 15.099  1.00 30.64  ? 168 GLU C CA  1 
ATOM   7718  C  C   . GLU C 1 189 ? -61.499 -16.279 15.083  1.00 28.90  ? 168 GLU C C   1 
ATOM   7719  O  O   . GLU C 1 189 ? -60.415 -16.499 14.518  1.00 30.50  ? 168 GLU C O   1 
ATOM   7720  C  CB  . GLU C 1 189 ? -61.802 -14.168 16.437  1.00 30.47  ? 168 GLU C CB  1 
ATOM   7721  C  CG  . GLU C 1 189 ? -60.333 -14.225 16.829  1.00 43.60  ? 168 GLU C CG  1 
ATOM   7722  C  CD  . GLU C 1 189 ? -59.978 -13.266 17.956  1.00 65.74  ? 168 GLU C CD  1 
ATOM   7723  O  OE1 . GLU C 1 189 ? -60.398 -12.087 17.892  1.00 81.31  ? 168 GLU C OE1 1 
ATOM   7724  O  OE2 . GLU C 1 189 ? -59.282 -13.691 18.905  1.00 63.40  ? 168 GLU C OE2 1 
ATOM   7725  N  N   . LEU C 1 190 ? -62.187 -17.239 15.708  1.00 25.05  ? 169 LEU C N   1 
ATOM   7726  C  CA  . LEU C 1 190 ? -61.726 -18.620 15.727  1.00 29.01  ? 169 LEU C CA  1 
ATOM   7727  C  C   . LEU C 1 190 ? -61.752 -19.241 14.335  1.00 32.53  ? 169 LEU C C   1 
ATOM   7728  O  O   . LEU C 1 190 ? -60.828 -19.977 13.974  1.00 25.55  ? 169 LEU C O   1 
ATOM   7729  C  CB  . LEU C 1 190 ? -62.578 -19.441 16.700  1.00 29.01  ? 169 LEU C CB  1 
ATOM   7730  C  CG  . LEU C 1 190 ? -62.362 -19.052 18.165  1.00 35.08  ? 169 LEU C CG  1 
ATOM   7731  C  CD1 . LEU C 1 190 ? -63.519 -19.578 19.035  1.00 35.41  ? 169 LEU C CD1 1 
ATOM   7732  C  CD2 . LEU C 1 190 ? -61.030 -19.589 18.631  1.00 27.87  ? 169 LEU C CD2 1 
ATOM   7733  N  N   . VAL C 1 191 ? -62.813 -18.988 13.547  1.00 27.99  ? 170 VAL C N   1 
ATOM   7734  C  CA  . VAL C 1 191 ? -62.822 -19.465 12.159  1.00 28.19  ? 170 VAL C CA  1 
ATOM   7735  C  C   . VAL C 1 191 ? -61.663 -18.850 11.384  1.00 27.93  ? 170 VAL C C   1 
ATOM   7736  O  O   . VAL C 1 191 ? -60.989 -19.530 10.593  1.00 24.68  ? 170 VAL C O   1 
ATOM   7737  C  CB  . VAL C 1 191 ? -64.185 -19.162 11.501  1.00 26.85  ? 170 VAL C CB  1 
ATOM   7738  C  CG1 . VAL C 1 191 ? -64.153 -19.481 10.003  1.00 24.92  ? 170 VAL C CG1 1 
ATOM   7739  C  CG2 . VAL C 1 191 ? -65.266 -19.999 12.202  1.00 28.60  ? 170 VAL C CG2 1 
ATOM   7740  N  N   . GLY C 1 192 ? -61.389 -17.566 11.637  1.00 25.46  ? 171 GLY C N   1 
ATOM   7741  C  CA  . GLY C 1 192 ? -60.242 -16.907 11.028  1.00 25.02  ? 171 GLY C CA  1 
ATOM   7742  C  C   . GLY C 1 192 ? -58.915 -17.567 11.358  1.00 25.25  ? 171 GLY C C   1 
ATOM   7743  O  O   . GLY C 1 192 ? -58.027 -17.623 10.505  1.00 27.76  ? 171 GLY C O   1 
ATOM   7744  N  N   . ARG C 1 193 ? -58.742 -18.055 12.607  1.00 25.33  ? 172 ARG C N   1 
ATOM   7745  C  CA  . ARG C 1 193 ? -57.528 -18.810 12.944  1.00 28.84  ? 172 ARG C CA  1 
ATOM   7746  C  C   . ARG C 1 193 ? -57.461 -20.109 12.149  1.00 30.95  ? 172 ARG C C   1 
ATOM   7747  O  O   . ARG C 1 193 ? -56.392 -20.513 11.666  1.00 27.78  ? 172 ARG C O   1 
ATOM   7748  C  CB  . ARG C 1 193 ? -57.472 -19.139 14.435  1.00 28.67  ? 172 ARG C CB  1 
ATOM   7749  C  CG  . ARG C 1 193 ? -57.404 -17.932 15.413  1.00 31.31  ? 172 ARG C CG  1 
ATOM   7750  C  CD  . ARG C 1 193 ? -57.285 -18.501 16.848  1.00 32.40  ? 172 ARG C CD  1 
ATOM   7751  N  NE  . ARG C 1 193 ? -57.363 -17.469 17.878  1.00 32.89  ? 172 ARG C NE  1 
ATOM   7752  C  CZ  . ARG C 1 193 ? -56.356 -16.683 18.223  1.00 39.18  ? 172 ARG C CZ  1 
ATOM   7753  N  NH1 . ARG C 1 193 ? -55.179 -16.765 17.620  1.00 30.40  ? 172 ARG C NH1 1 
ATOM   7754  N  NH2 . ARG C 1 193 ? -56.533 -15.789 19.197  1.00 35.00  ? 172 ARG C NH2 1 
ATOM   7755  N  N   . MET C 1 194 ? -58.600 -20.787 12.003  1.00 25.44  ? 173 MET C N   1 
ATOM   7756  C  CA  . MET C 1 194 ? -58.610 -22.010 11.200  1.00 20.98  ? 173 MET C CA  1 
ATOM   7757  C  C   . MET C 1 194 ? -58.221 -21.724 9.749   1.00 22.30  ? 173 MET C C   1 
ATOM   7758  O  O   . MET C 1 194 ? -57.472 -22.498 9.151   1.00 24.46  ? 173 MET C O   1 
ATOM   7759  C  CB  . MET C 1 194 ? -59.994 -22.675 11.285  1.00 23.11  ? 173 MET C CB  1 
ATOM   7760  C  CG  . MET C 1 194 ? -60.240 -23.306 12.640  1.00 31.68  ? 173 MET C CG  1 
ATOM   7761  S  SD  . MET C 1 194 ? -61.948 -23.910 12.706  1.00 28.73  ? 173 MET C SD  1 
ATOM   7762  C  CE  . MET C 1 194 ? -61.817 -24.914 14.208  1.00 25.15  ? 173 MET C CE  1 
ATOM   7763  N  N   . ILE C 1 195 ? -58.711 -20.622 9.170   1.00 22.99  ? 174 ILE C N   1 
ATOM   7764  C  CA  . ILE C 1 195 ? -58.349 -20.284 7.791   1.00 25.47  ? 174 ILE C CA  1 
ATOM   7765  C  C   . ILE C 1 195 ? -56.847 -20.021 7.681   1.00 27.89  ? 174 ILE C C   1 
ATOM   7766  O  O   . ILE C 1 195 ? -56.176 -20.477 6.747   1.00 22.35  ? 174 ILE C O   1 
ATOM   7767  C  CB  . ILE C 1 195 ? -59.155 -19.066 7.307   1.00 22.47  ? 174 ILE C CB  1 
ATOM   7768  C  CG1 . ILE C 1 195 ? -60.665 -19.380 7.260   1.00 21.51  ? 174 ILE C CG1 1 
ATOM   7769  C  CG2 . ILE C 1 195 ? -58.694 -18.645 5.931   1.00 23.93  ? 174 ILE C CG2 1 
ATOM   7770  C  CD1 . ILE C 1 195 ? -61.535 -18.105 6.994   1.00 22.55  ? 174 ILE C CD1 1 
ATOM   7771  N  N   . THR C 1 196 ? -56.312 -19.234 8.608   1.00 24.45  ? 175 THR C N   1 
ATOM   7772  C  CA  . THR C 1 196 ? -54.876 -18.976 8.615   1.00 23.42  ? 175 THR C CA  1 
ATOM   7773  C  C   . THR C 1 196 ? -54.110 -20.277 8.723   1.00 24.08  ? 175 THR C C   1 
ATOM   7774  O  O   . THR C 1 196 ? -53.123 -20.486 8.013   1.00 27.58  ? 175 THR C O   1 
ATOM   7775  C  CB  . THR C 1 196 ? -54.543 -18.050 9.788   1.00 25.67  ? 175 THR C CB  1 
ATOM   7776  O  OG1 . THR C 1 196 ? -55.219 -16.828 9.576   1.00 24.42  ? 175 THR C OG1 1 
ATOM   7777  C  CG2 . THR C 1 196 ? -53.033 -17.804 9.925   1.00 29.96  ? 175 THR C CG2 1 
ATOM   7778  N  N   . LEU C 1 197 ? -54.553 -21.174 9.616   1.00 23.90  ? 176 LEU C N   1 
ATOM   7779  C  CA  . LEU C 1 197 ? -53.868 -22.450 9.757   1.00 21.08  ? 176 LEU C CA  1 
ATOM   7780  C  C   . LEU C 1 197 ? -53.892 -23.204 8.438   1.00 25.47  ? 176 LEU C C   1 
ATOM   7781  O  O   . LEU C 1 197 ? -52.852 -23.657 7.947   1.00 23.81  ? 176 LEU C O   1 
ATOM   7782  C  CB  . LEU C 1 197 ? -54.505 -23.286 10.883  1.00 23.88  ? 176 LEU C CB  1 
ATOM   7783  C  CG  . LEU C 1 197 ? -53.860 -24.621 11.287  1.00 31.48  ? 176 LEU C CG  1 
ATOM   7784  C  CD1 . LEU C 1 197 ? -54.371 -25.031 12.680  1.00 32.04  ? 176 LEU C CD1 1 
ATOM   7785  C  CD2 . LEU C 1 197 ? -54.153 -25.748 10.317  1.00 31.20  ? 176 LEU C CD2 1 
ATOM   7786  N  N   . LEU C 1 198 ? -55.081 -23.329 7.839   1.00 23.86  ? 177 LEU C N   1 
ATOM   7787  C  CA  . LEU C 1 198 ? -55.217 -24.099 6.607   1.00 24.59  ? 177 LEU C CA  1 
ATOM   7788  C  C   . LEU C 1 198 ? -54.437 -23.474 5.461   1.00 22.10  ? 177 LEU C C   1 
ATOM   7789  O  O   . LEU C 1 198 ? -53.987 -24.190 4.565   1.00 26.03  ? 177 LEU C O   1 
ATOM   7790  C  CB  . LEU C 1 198 ? -56.702 -24.205 6.230   1.00 19.26  ? 177 LEU C CB  1 
ATOM   7791  C  CG  . LEU C 1 198 ? -57.529 -25.148 7.110   1.00 23.11  ? 177 LEU C CG  1 
ATOM   7792  C  CD1 . LEU C 1 198 ? -58.990 -24.804 6.878   1.00 22.87  ? 177 LEU C CD1 1 
ATOM   7793  C  CD2 . LEU C 1 198 ? -57.233 -26.598 6.678   1.00 24.07  ? 177 LEU C CD2 1 
ATOM   7794  N  N   . ASP C 1 199 ? -54.284 -22.150 5.464   1.00 21.37  ? 178 ASP C N   1 
ATOM   7795  C  CA  . ASP C 1 199 ? -53.612 -21.471 4.362   1.00 23.95  ? 178 ASP C CA  1 
ATOM   7796  C  C   . ASP C 1 199 ? -52.096 -21.499 4.499   1.00 26.41  ? 178 ASP C C   1 
ATOM   7797  O  O   . ASP C 1 199 ? -51.395 -21.054 3.579   1.00 27.74  ? 178 ASP C O   1 
ATOM   7798  C  CB  . ASP C 1 199 ? -54.083 -20.011 4.291   1.00 21.37  ? 178 ASP C CB  1 
ATOM   7799  C  CG  . ASP C 1 199 ? -54.294 -19.504 2.851   1.00 30.17  ? 178 ASP C CG  1 
ATOM   7800  O  OD1 . ASP C 1 199 ? -54.296 -20.285 1.866   1.00 29.36  ? 178 ASP C OD1 1 
ATOM   7801  O  OD2 . ASP C 1 199 ? -54.461 -18.288 2.725   1.00 34.90  ? 178 ASP C OD2 1 
ATOM   7802  N  N   . ASN C 1 200 ? -51.569 -22.021 5.598   1.00 24.24  ? 179 ASN C N   1 
ATOM   7803  C  CA  . ASN C 1 200 ? -50.137 -21.898 5.857   1.00 27.94  ? 179 ASN C CA  1 
ATOM   7804  C  C   . ASN C 1 200 ? -49.420 -23.180 6.241   1.00 26.42  ? 179 ASN C C   1 
ATOM   7805  O  O   . ASN C 1 200 ? -48.190 -23.221 6.105   1.00 26.09  ? 179 ASN C O   1 
ATOM   7806  C  CB  . ASN C 1 200 ? -49.897 -20.843 6.946   1.00 23.72  ? 179 ASN C CB  1 
ATOM   7807  C  CG  . ASN C 1 200 ? -50.044 -19.434 6.416   1.00 27.83  ? 179 ASN C CG  1 
ATOM   7808  O  OD1 . ASN C 1 200 ? -49.126 -18.909 5.792   1.00 28.07  ? 179 ASN C OD1 1 
ATOM   7809  N  ND2 . ASN C 1 200 ? -51.197 -18.798 6.677   1.00 26.13  ? 179 ASN C ND2 1 
ATOM   7810  N  N   . PHE C 1 201 ? -50.117 -24.232 6.682   1.00 23.82  ? 180 PHE C N   1 
ATOM   7811  C  CA  . PHE C 1 201 ? -49.426 -25.417 7.201   1.00 23.93  ? 180 PHE C CA  1 
ATOM   7812  C  C   . PHE C 1 201 ? -48.557 -26.123 6.159   1.00 29.05  ? 180 PHE C C   1 
ATOM   7813  O  O   . PHE C 1 201 ? -47.680 -26.910 6.533   1.00 31.77  ? 180 PHE C O   1 
ATOM   7814  C  CB  . PHE C 1 201 ? -50.448 -26.419 7.754   1.00 22.56  ? 180 PHE C CB  1 
ATOM   7815  C  CG  . PHE C 1 201 ? -51.157 -27.193 6.675   1.00 27.55  ? 180 PHE C CG  1 
ATOM   7816  C  CD1 . PHE C 1 201 ? -52.218 -26.618 5.990   1.00 24.48  ? 180 PHE C CD1 1 
ATOM   7817  C  CD2 . PHE C 1 201 ? -50.740 -28.476 6.330   1.00 24.80  ? 180 PHE C CD2 1 
ATOM   7818  C  CE1 . PHE C 1 201 ? -52.865 -27.326 4.951   1.00 22.07  ? 180 PHE C CE1 1 
ATOM   7819  C  CE2 . PHE C 1 201 ? -51.381 -29.193 5.326   1.00 27.64  ? 180 PHE C CE2 1 
ATOM   7820  C  CZ  . PHE C 1 201 ? -52.450 -28.613 4.634   1.00 24.17  ? 180 PHE C CZ  1 
ATOM   7821  N  N   . GLY C 1 202 ? -48.772 -25.893 4.867   1.00 27.07  ? 181 GLY C N   1 
ATOM   7822  C  CA  . GLY C 1 202 ? -48.094 -26.748 3.905   1.00 37.22  ? 181 GLY C CA  1 
ATOM   7823  C  C   . GLY C 1 202 ? -46.749 -26.280 3.377   1.00 37.36  ? 181 GLY C C   1 
ATOM   7824  O  O   . GLY C 1 202 ? -46.170 -26.958 2.516   1.00 28.57  ? 181 GLY C O   1 
ATOM   7825  N  N   . THR C 1 203 ? -46.232 -25.146 3.847   1.00 29.81  ? 182 THR C N   1 
ATOM   7826  C  CA  . THR C 1 203 ? -45.058 -24.516 3.247   1.00 27.45  ? 182 THR C CA  1 
ATOM   7827  C  C   . THR C 1 203 ? -43.998 -24.235 4.301   1.00 31.91  ? 182 THR C C   1 
ATOM   7828  O  O   . THR C 1 203 ? -44.299 -24.098 5.486   1.00 30.29  ? 182 THR C O   1 
ATOM   7829  C  CB  . THR C 1 203 ? -45.411 -23.194 2.568   1.00 37.49  ? 182 THR C CB  1 
ATOM   7830  O  OG1 . THR C 1 203 ? -45.842 -22.257 3.566   1.00 34.82  ? 182 THR C OG1 1 
ATOM   7831  C  CG2 . THR C 1 203 ? -46.536 -23.407 1.560   1.00 43.24  ? 182 THR C CG2 1 
ATOM   7832  N  N   . ALA C 1 204 ? -42.753 -24.092 3.842   1.00 30.37  ? 183 ALA C N   1 
ATOM   7833  C  CA  . ALA C 1 204 ? -41.668 -23.763 4.763   1.00 41.69  ? 183 ALA C CA  1 
ATOM   7834  C  C   . ALA C 1 204 ? -41.878 -22.390 5.388   1.00 36.16  ? 183 ALA C C   1 
ATOM   7835  O  O   . ALA C 1 204 ? -41.683 -22.216 6.604   1.00 37.48  ? 183 ALA C O   1 
ATOM   7836  C  CB  . ALA C 1 204 ? -40.317 -23.832 4.045   1.00 47.49  ? 183 ALA C CB  1 
ATOM   7837  N  N   . THR C 1 205 ? -42.339 -21.417 4.598   1.00 31.81  ? 184 THR C N   1 
ATOM   7838  C  CA  . THR C 1 205 ? -42.463 -20.069 5.136   1.00 32.05  ? 184 THR C CA  1 
ATOM   7839  C  C   . THR C 1 205 ? -43.688 -19.908 6.024   1.00 33.19  ? 184 THR C C   1 
ATOM   7840  O  O   . THR C 1 205 ? -43.657 -19.076 6.939   1.00 24.54  ? 184 THR C O   1 
ATOM   7841  C  CB  . THR C 1 205 ? -42.509 -19.024 4.028   1.00 36.68  ? 184 THR C CB  1 
ATOM   7842  O  OG1 . THR C 1 205 ? -43.680 -19.218 3.233   1.00 44.80  ? 184 THR C OG1 1 
ATOM   7843  C  CG2 . THR C 1 205 ? -41.270 -19.127 3.149   1.00 40.34  ? 184 THR C CG2 1 
ATOM   7844  N  N   . GLY C 1 206 ? -44.757 -20.675 5.780   1.00 24.41  ? 185 GLY C N   1 
ATOM   7845  C  CA  . GLY C 1 206 ? -45.996 -20.526 6.535   1.00 24.06  ? 185 GLY C CA  1 
ATOM   7846  C  C   . GLY C 1 206 ? -46.117 -21.399 7.774   1.00 22.85  ? 185 GLY C C   1 
ATOM   7847  O  O   . GLY C 1 206 ? -46.967 -21.136 8.630   1.00 25.97  ? 185 GLY C O   1 
ATOM   7848  N  N   . THR C 1 207 ? -45.308 -22.448 7.889   1.00 23.38  ? 186 THR C N   1 
ATOM   7849  C  CA  . THR C 1 207 ? -45.481 -23.371 9.005   1.00 24.47  ? 186 THR C CA  1 
ATOM   7850  C  C   . THR C 1 207 ? -45.455 -22.684 10.368  1.00 25.19  ? 186 THR C C   1 
ATOM   7851  O  O   . THR C 1 207 ? -46.286 -23.046 11.225  1.00 27.48  ? 186 THR C O   1 
ATOM   7852  C  CB  . THR C 1 207 ? -44.431 -24.490 8.954   1.00 33.97  ? 186 THR C CB  1 
ATOM   7853  O  OG1 . THR C 1 207 ? -44.566 -25.197 7.714   1.00 50.64  ? 186 THR C OG1 1 
ATOM   7854  C  CG2 . THR C 1 207 ? -44.679 -25.466 10.069  1.00 24.55  ? 186 THR C CG2 1 
ATOM   7855  N  N   . PRO C 1 208 ? -44.592 -21.698 10.635  1.00 26.37  ? 187 PRO C N   1 
ATOM   7856  C  CA  . PRO C 1 208 ? -44.682 -21.031 11.960  1.00 24.88  ? 187 PRO C CA  1 
ATOM   7857  C  C   . PRO C 1 208 ? -46.051 -20.444 12.262  1.00 26.24  ? 187 PRO C C   1 
ATOM   7858  O  O   . PRO C 1 208 ? -46.543 -20.623 13.382  1.00 25.16  ? 187 PRO C O   1 
ATOM   7859  C  CB  . PRO C 1 208 ? -43.614 -19.932 11.896  1.00 23.46  ? 187 PRO C CB  1 
ATOM   7860  C  CG  . PRO C 1 208 ? -42.606 -20.438 10.834  1.00 26.14  ? 187 PRO C CG  1 
ATOM   7861  C  CD  . PRO C 1 208 ? -43.487 -21.160 9.812   1.00 25.43  ? 187 PRO C CD  1 
ATOM   7862  N  N   . LYS C 1 209 ? -46.675 -19.743 11.307  1.00 23.23  ? 188 LYS C N   1 
ATOM   7863  C  CA  . LYS C 1 209 ? -48.008 -19.187 11.549  1.00 25.69  ? 188 LYS C CA  1 
ATOM   7864  C  C   . LYS C 1 209 ? -49.017 -20.288 11.813  1.00 28.69  ? 188 LYS C C   1 
ATOM   7865  O  O   . LYS C 1 209 ? -49.910 -20.147 12.662  1.00 26.49  ? 188 LYS C O   1 
ATOM   7866  C  CB  . LYS C 1 209 ? -48.483 -18.358 10.349  1.00 26.18  ? 188 LYS C CB  1 
ATOM   7867  C  CG  . LYS C 1 209 ? -47.904 -16.978 10.298  1.00 48.04  ? 188 LYS C CG  1 
ATOM   7868  C  CD  . LYS C 1 209 ? -48.096 -16.340 8.930   1.00 42.47  ? 188 LYS C CD  1 
ATOM   7869  C  CE  . LYS C 1 209 ? -49.326 -15.478 8.928   1.00 51.17  ? 188 LYS C CE  1 
ATOM   7870  N  NZ  . LYS C 1 209 ? -49.184 -14.393 7.920   1.00 60.67  ? 188 LYS C NZ  1 
ATOM   7871  N  N   . ALA C 1 210 ? -48.880 -21.408 11.106  1.00 28.15  ? 189 ALA C N   1 
ATOM   7872  C  CA  . ALA C 1 210 ? -49.820 -22.500 11.293  1.00 25.33  ? 189 ALA C CA  1 
ATOM   7873  C  C   . ALA C 1 210 ? -49.727 -23.048 12.700  1.00 24.80  ? 189 ALA C C   1 
ATOM   7874  O  O   . ALA C 1 210 ? -50.750 -23.323 13.330  1.00 24.07  ? 189 ALA C O   1 
ATOM   7875  C  CB  . ALA C 1 210 ? -49.568 -23.609 10.267  1.00 24.33  ? 189 ALA C CB  1 
ATOM   7876  N  N   . PHE C 1 211 ? -48.502 -23.220 13.216  1.00 25.52  ? 190 PHE C N   1 
ATOM   7877  C  CA  . PHE C 1 211 ? -48.371 -23.747 14.564  1.00 26.35  ? 190 PHE C CA  1 
ATOM   7878  C  C   . PHE C 1 211 ? -48.791 -22.729 15.611  1.00 22.28  ? 190 PHE C C   1 
ATOM   7879  O  O   . PHE C 1 211 ? -49.306 -23.122 16.659  1.00 26.73  ? 190 PHE C O   1 
ATOM   7880  C  CB  . PHE C 1 211 ? -46.950 -24.232 14.818  1.00 25.58  ? 190 PHE C CB  1 
ATOM   7881  C  CG  . PHE C 1 211 ? -46.735 -25.671 14.422  1.00 27.25  ? 190 PHE C CG  1 
ATOM   7882  C  CD1 . PHE C 1 211 ? -47.160 -26.704 15.243  1.00 29.14  ? 190 PHE C CD1 1 
ATOM   7883  C  CD2 . PHE C 1 211 ? -46.103 -25.975 13.238  1.00 28.67  ? 190 PHE C CD2 1 
ATOM   7884  C  CE1 . PHE C 1 211 ? -46.963 -28.048 14.865  1.00 29.95  ? 190 PHE C CE1 1 
ATOM   7885  C  CE2 . PHE C 1 211 ? -45.899 -27.292 12.841  1.00 30.58  ? 190 PHE C CE2 1 
ATOM   7886  C  CZ  . PHE C 1 211 ? -46.325 -28.338 13.658  1.00 32.07  ? 190 PHE C CZ  1 
ATOM   7887  N  N   . TRP C 1 212 ? -48.583 -21.427 15.351  1.00 25.27  ? 191 TRP C N   1 
ATOM   7888  C  CA  . TRP C 1 212 ? -49.117 -20.398 16.252  1.00 25.17  ? 191 TRP C CA  1 
ATOM   7889  C  C   . TRP C 1 212 ? -50.623 -20.566 16.430  1.00 33.48  ? 191 TRP C C   1 
ATOM   7890  O  O   . TRP C 1 212 ? -51.143 -20.585 17.557  1.00 27.65  ? 191 TRP C O   1 
ATOM   7891  C  CB  . TRP C 1 212 ? -48.796 -19.006 15.715  1.00 26.23  ? 191 TRP C CB  1 
ATOM   7892  C  CG  . TRP C 1 212 ? -49.203 -17.872 16.661  1.00 27.85  ? 191 TRP C CG  1 
ATOM   7893  C  CD1 . TRP C 1 212 ? -50.476 -17.447 16.940  1.00 33.71  ? 191 TRP C CD1 1 
ATOM   7894  C  CD2 . TRP C 1 212 ? -48.321 -17.019 17.427  1.00 33.67  ? 191 TRP C CD2 1 
ATOM   7895  N  NE1 . TRP C 1 212 ? -50.442 -16.397 17.851  1.00 28.17  ? 191 TRP C NE1 1 
ATOM   7896  C  CE2 . TRP C 1 212 ? -49.133 -16.112 18.150  1.00 31.20  ? 191 TRP C CE2 1 
ATOM   7897  C  CE3 . TRP C 1 212 ? -46.926 -16.935 17.564  1.00 30.18  ? 191 TRP C CE3 1 
ATOM   7898  C  CZ2 . TRP C 1 212 ? -48.591 -15.128 18.998  1.00 34.25  ? 191 TRP C CZ2 1 
ATOM   7899  C  CZ3 . TRP C 1 212 ? -46.389 -15.954 18.403  1.00 30.31  ? 191 TRP C CZ3 1 
ATOM   7900  C  CH2 . TRP C 1 212 ? -47.220 -15.062 19.103  1.00 27.64  ? 191 TRP C CH2 1 
ATOM   7901  N  N   . GLN C 1 213 ? -51.338 -20.722 15.326  1.00 25.11  ? 192 GLN C N   1 
ATOM   7902  C  CA  . GLN C 1 213 ? -52.787 -20.860 15.415  1.00 25.11  ? 192 GLN C CA  1 
ATOM   7903  C  C   . GLN C 1 213 ? -53.188 -22.210 15.998  1.00 27.93  ? 192 GLN C C   1 
ATOM   7904  O  O   . GLN C 1 213 ? -54.150 -22.291 16.772  1.00 27.42  ? 192 GLN C O   1 
ATOM   7905  C  CB  . GLN C 1 213 ? -53.425 -20.641 14.041  1.00 26.58  ? 192 GLN C CB  1 
ATOM   7906  C  CG  . GLN C 1 213 ? -53.205 -19.254 13.448  1.00 27.66  ? 192 GLN C CG  1 
ATOM   7907  C  CD  . GLN C 1 213 ? -53.625 -18.121 14.394  1.00 33.50  ? 192 GLN C CD  1 
ATOM   7908  O  OE1 . GLN C 1 213 ? -54.398 -18.319 15.337  1.00 31.20  ? 192 GLN C OE1 1 
ATOM   7909  N  NE2 . GLN C 1 213 ? -53.090 -16.927 14.148  1.00 32.38  ? 192 GLN C NE2 1 
ATOM   7910  N  N   . ARG C 1 214 ? -52.476 -23.284 15.655  1.00 23.87  ? 193 ARG C N   1 
ATOM   7911  C  CA  . ARG C 1 214 ? -52.807 -24.574 16.256  1.00 23.86  ? 193 ARG C CA  1 
ATOM   7912  C  C   . ARG C 1 214 ? -52.714 -24.505 17.782  1.00 28.06  ? 193 ARG C C   1 
ATOM   7913  O  O   . ARG C 1 214 ? -53.605 -24.987 18.495  1.00 25.85  ? 193 ARG C O   1 
ATOM   7914  C  CB  . ARG C 1 214 ? -51.886 -25.660 15.692  1.00 24.99  ? 193 ARG C CB  1 
ATOM   7915  C  CG  . ARG C 1 214 ? -51.704 -26.897 16.553  1.00 32.79  ? 193 ARG C CG  1 
ATOM   7916  C  CD  . ARG C 1 214 ? -52.988 -27.729 16.630  1.00 30.24  ? 193 ARG C CD  1 
ATOM   7917  N  NE  . ARG C 1 214 ? -53.620 -27.902 15.331  1.00 27.70  ? 193 ARG C NE  1 
ATOM   7918  C  CZ  . ARG C 1 214 ? -54.782 -28.521 15.146  1.00 35.69  ? 193 ARG C CZ  1 
ATOM   7919  N  NH1 . ARG C 1 214 ? -55.490 -28.978 16.169  1.00 30.05  ? 193 ARG C NH1 1 
ATOM   7920  N  NH2 . ARG C 1 214 ? -55.235 -28.706 13.901  1.00 29.68  ? 193 ARG C NH2 1 
ATOM   7921  N  N   . ARG C 1 215 ? -51.657 -23.875 18.307  1.00 25.88  ? 194 ARG C N   1 
ATOM   7922  C  CA  . ARG C 1 215 ? -51.542 -23.772 19.763  1.00 30.38  ? 194 ARG C CA  1 
ATOM   7923  C  C   . ARG C 1 215 ? -52.728 -23.006 20.356  1.00 31.12  ? 194 ARG C C   1 
ATOM   7924  O  O   . ARG C 1 215 ? -53.319 -23.434 21.357  1.00 30.39  ? 194 ARG C O   1 
ATOM   7925  C  CB  . ARG C 1 215 ? -50.195 -23.120 20.131  1.00 31.94  ? 194 ARG C CB  1 
ATOM   7926  C  CG  . ARG C 1 215 ? -49.917 -22.915 21.637  1.00 41.71  ? 194 ARG C CG  1 
ATOM   7927  C  CD  . ARG C 1 215 ? -49.998 -24.187 22.445  1.00 44.36  ? 194 ARG C CD  1 
ATOM   7928  N  NE  . ARG C 1 215 ? -49.189 -25.266 21.887  1.00 77.46  ? 194 ARG C NE  1 
ATOM   7929  C  CZ  . ARG C 1 215 ? -47.925 -25.506 22.210  1.00 80.56  ? 194 ARG C CZ  1 
ATOM   7930  N  NH1 . ARG C 1 215 ? -47.273 -24.734 23.068  1.00 71.16  ? 194 ARG C NH1 1 
ATOM   7931  N  NH2 . ARG C 1 215 ? -47.301 -26.547 21.659  1.00 66.82  ? 194 ARG C NH2 1 
ATOM   7932  N  N   . GLN C 1 216 ? -53.107 -21.874 19.746  1.00 25.16  ? 195 GLN C N   1 
ATOM   7933  C  CA  . GLN C 1 216 ? -54.191 -21.074 20.311  1.00 28.37  ? 195 GLN C CA  1 
ATOM   7934  C  C   . GLN C 1 216 ? -55.525 -21.803 20.205  1.00 32.09  ? 195 GLN C C   1 
ATOM   7935  O  O   . GLN C 1 216 ? -56.344 -21.752 21.130  1.00 29.02  ? 195 GLN C O   1 
ATOM   7936  C  CB  . GLN C 1 216 ? -54.302 -19.714 19.612  1.00 28.42  ? 195 GLN C CB  1 
ATOM   7937  C  CG  . GLN C 1 216 ? -53.093 -18.798 19.772  1.00 37.55  ? 195 GLN C CG  1 
ATOM   7938  C  CD  . GLN C 1 216 ? -52.764 -18.500 21.241  1.00 47.46  ? 195 GLN C CD  1 
ATOM   7939  O  OE1 . GLN C 1 216 ? -51.718 -18.899 21.754  1.00 49.58  ? 195 GLN C OE1 1 
ATOM   7940  N  NE2 . GLN C 1 216 ? -53.651 -17.783 21.908  1.00 49.40  ? 195 GLN C NE2 1 
ATOM   7941  N  N   . LEU C 1 217 ? -55.771 -22.453 19.068  1.00 27.61  ? 196 LEU C N   1 
ATOM   7942  C  CA  . LEU C 1 217 ? -57.002 -23.213 18.892  1.00 31.88  ? 196 LEU C CA  1 
ATOM   7943  C  C   . LEU C 1 217 ? -57.086 -24.380 19.873  1.00 27.01  ? 196 LEU C C   1 
ATOM   7944  O  O   . LEU C 1 217 ? -58.150 -24.622 20.455  1.00 31.52  ? 196 LEU C O   1 
ATOM   7945  C  CB  . LEU C 1 217 ? -57.102 -23.708 17.443  1.00 27.23  ? 196 LEU C CB  1 
ATOM   7946  C  CG  . LEU C 1 217 ? -57.431 -22.642 16.396  1.00 25.98  ? 196 LEU C CG  1 
ATOM   7947  C  CD1 . LEU C 1 217 ? -57.091 -23.094 14.959  1.00 31.36  ? 196 LEU C CD1 1 
ATOM   7948  C  CD2 . LEU C 1 217 ? -58.904 -22.278 16.474  1.00 30.28  ? 196 LEU C CD2 1 
ATOM   7949  N  N   . ASP C 1 218 ? -55.979 -25.122 20.067  1.00 26.01  ? 197 ASP C N   1 
ATOM   7950  C  CA  . ASP C 1 218 ? -55.974 -26.221 21.034  1.00 30.30  ? 197 ASP C CA  1 
ATOM   7951  C  C   . ASP C 1 218 ? -56.277 -25.724 22.452  1.00 30.91  ? 197 ASP C C   1 
ATOM   7952  O  O   . ASP C 1 218 ? -57.001 -26.378 23.213  1.00 30.12  ? 197 ASP C O   1 
ATOM   7953  C  CB  . ASP C 1 218 ? -54.621 -26.922 21.026  1.00 30.47  ? 197 ASP C CB  1 
ATOM   7954  C  CG  . ASP C 1 218 ? -54.414 -27.809 19.812  1.00 40.51  ? 197 ASP C CG  1 
ATOM   7955  O  OD1 . ASP C 1 218 ? -55.329 -27.913 18.952  1.00 41.56  ? 197 ASP C OD1 1 
ATOM   7956  O  OD2 . ASP C 1 218 ? -53.317 -28.401 19.721  1.00 41.64  ? 197 ASP C OD2 1 
ATOM   7957  N  N   . ASN C 1 219 ? -55.674 -24.606 22.838  1.00 32.87  ? 198 ASN C N   1 
ATOM   7958  C  CA  . ASN C 1 219 ? -55.961 -24.005 24.142  1.00 32.41  ? 198 ASN C CA  1 
ATOM   7959  C  C   . ASN C 1 219 ? -57.439 -23.645 24.277  1.00 31.64  ? 198 ASN C C   1 
ATOM   7960  O  O   . ASN C 1 219 ? -58.086 -23.988 25.278  1.00 30.90  ? 198 ASN C O   1 
ATOM   7961  C  CB  . ASN C 1 219 ? -55.086 -22.764 24.327  1.00 30.99  ? 198 ASN C CB  1 
ATOM   7962  C  CG  . ASN C 1 219 ? -53.623 -23.124 24.591  1.00 32.07  ? 198 ASN C CG  1 
ATOM   7963  O  OD1 . ASN C 1 219 ? -53.301 -24.280 24.848  1.00 34.26  ? 198 ASN C OD1 1 
ATOM   7964  N  ND2 . ASN C 1 219 ? -52.741 -22.131 24.531  1.00 38.05  ? 198 ASN C ND2 1 
ATOM   7965  N  N   . TRP C 1 220 ? -57.983 -22.945 23.276  1.00 30.22  ? 199 TRP C N   1 
ATOM   7966  C  CA  . TRP C 1 220 ? -59.403 -22.616 23.255  1.00 32.06  ? 199 TRP C CA  1 
ATOM   7967  C  C   . TRP C 1 220 ? -60.271 -23.861 23.361  1.00 34.66  ? 199 TRP C C   1 
ATOM   7968  O  O   . TRP C 1 220 ? -61.191 -23.919 24.185  1.00 30.14  ? 199 TRP C O   1 
ATOM   7969  C  CB  . TRP C 1 220 ? -59.763 -21.858 21.985  1.00 29.63  ? 199 TRP C CB  1 
ATOM   7970  C  CG  . TRP C 1 220 ? -61.259 -21.907 21.731  1.00 28.90  ? 199 TRP C CG  1 
ATOM   7971  C  CD1 . TRP C 1 220 ? -62.235 -21.219 22.397  1.00 34.97  ? 199 TRP C CD1 1 
ATOM   7972  C  CD2 . TRP C 1 220 ? -61.935 -22.709 20.753  1.00 32.26  ? 199 TRP C CD2 1 
ATOM   7973  N  NE1 . TRP C 1 220 ? -63.477 -21.551 21.902  1.00 32.95  ? 199 TRP C NE1 1 
ATOM   7974  C  CE2 . TRP C 1 220 ? -63.322 -22.465 20.894  1.00 36.10  ? 199 TRP C CE2 1 
ATOM   7975  C  CE3 . TRP C 1 220 ? -61.503 -23.610 19.770  1.00 29.53  ? 199 TRP C CE3 1 
ATOM   7976  C  CZ2 . TRP C 1 220 ? -64.280 -23.075 20.071  1.00 34.68  ? 199 TRP C CZ2 1 
ATOM   7977  C  CZ3 . TRP C 1 220 ? -62.457 -24.225 18.961  1.00 36.42  ? 199 TRP C CZ3 1 
ATOM   7978  C  CH2 . TRP C 1 220 ? -63.828 -23.954 19.121  1.00 33.24  ? 199 TRP C CH2 1 
ATOM   7979  N  N   . ALA C 1 221 ? -59.998 -24.872 22.525  1.00 30.61  ? 200 ALA C N   1 
ATOM   7980  C  CA  . ALA C 1 221 ? -60.868 -26.041 22.493  1.00 29.33  ? 200 ALA C CA  1 
ATOM   7981  C  C   . ALA C 1 221 ? -60.765 -26.840 23.787  1.00 33.20  ? 200 ALA C C   1 
ATOM   7982  O  O   . ALA C 1 221 ? -61.772 -27.360 24.276  1.00 32.90  ? 200 ALA C O   1 
ATOM   7983  C  CB  . ALA C 1 221 ? -60.546 -26.920 21.276  1.00 29.63  ? 200 ALA C CB  1 
ATOM   7984  N  N   . GLU C 1 222 ? -59.559 -26.970 24.347  1.00 31.02  ? 201 GLU C N   1 
ATOM   7985  C  CA  . GLU C 1 222 ? -59.418 -27.666 25.621  1.00 35.79  ? 201 GLU C CA  1 
ATOM   7986  C  C   . GLU C 1 222 ? -60.228 -26.968 26.708  1.00 34.26  ? 201 GLU C C   1 
ATOM   7987  O  O   . GLU C 1 222 ? -60.917 -27.626 27.502  1.00 34.87  ? 201 GLU C O   1 
ATOM   7988  C  CB  . GLU C 1 222 ? -57.947 -27.755 26.044  1.00 33.70  ? 201 GLU C CB  1 
ATOM   7989  C  CG  . GLU C 1 222 ? -57.786 -28.451 27.405  1.00 36.78  ? 201 GLU C CG  1 
ATOM   7990  C  CD  . GLU C 1 222 ? -56.337 -28.604 27.855  1.00 48.56  ? 201 GLU C CD  1 
ATOM   7991  O  OE1 . GLU C 1 222 ? -55.426 -28.261 27.079  1.00 40.66  ? 201 GLU C OE1 1 
ATOM   7992  O  OE2 . GLU C 1 222 ? -56.111 -29.073 28.995  1.00 45.01  ? 201 GLU C OE2 1 
ATOM   7993  N  N   . ALA C 1 223 ? -60.162 -25.635 26.754  1.00 32.89  ? 202 ALA C N   1 
ATOM   7994  C  CA  . ALA C 1 223 ? -60.914 -24.901 27.766  1.00 36.67  ? 202 ALA C CA  1 
ATOM   7995  C  C   . ALA C 1 223 ? -62.410 -25.117 27.595  1.00 42.08  ? 202 ALA C C   1 
ATOM   7996  O  O   . ALA C 1 223 ? -63.145 -25.279 28.582  1.00 41.92  ? 202 ALA C O   1 
ATOM   7997  C  CB  . ALA C 1 223 ? -60.567 -23.413 27.700  1.00 34.97  ? 202 ALA C CB  1 
ATOM   7998  N  N   . LEU C 1 224 ? -62.882 -25.154 26.344  1.00 38.61  ? 203 LEU C N   1 
ATOM   7999  C  CA  . LEU C 1 224 ? -64.310 -25.353 26.103  1.00 30.25  ? 203 LEU C CA  1 
ATOM   8000  C  C   . LEU C 1 224 ? -64.764 -26.745 26.540  1.00 34.88  ? 203 LEU C C   1 
ATOM   8001  O  O   . LEU C 1 224 ? -65.782 -26.882 27.227  1.00 36.23  ? 203 LEU C O   1 
ATOM   8002  C  CB  . LEU C 1 224 ? -64.632 -25.115 24.630  1.00 37.91  ? 203 LEU C CB  1 
ATOM   8003  C  CG  . LEU C 1 224 ? -66.071 -25.421 24.200  1.00 43.44  ? 203 LEU C CG  1 
ATOM   8004  C  CD1 . LEU C 1 224 ? -67.101 -24.523 24.872  1.00 34.48  ? 203 LEU C CD1 1 
ATOM   8005  C  CD2 . LEU C 1 224 ? -66.165 -25.312 22.681  1.00 38.47  ? 203 LEU C CD2 1 
ATOM   8006  N  N   . ILE C 1 225 ? -64.034 -27.796 26.145  1.00 32.36  ? 204 ILE C N   1 
ATOM   8007  C  CA  . ILE C 1 225 ? -64.390 -29.147 26.580  1.00 35.09  ? 204 ILE C CA  1 
ATOM   8008  C  C   . ILE C 1 225 ? -64.390 -29.233 28.109  1.00 41.84  ? 204 ILE C C   1 
ATOM   8009  O  O   . ILE C 1 225 ? -65.280 -29.845 28.714  1.00 32.97  ? 204 ILE C O   1 
ATOM   8010  C  CB  . ILE C 1 225 ? -63.431 -30.183 25.968  1.00 32.47  ? 204 ILE C CB  1 
ATOM   8011  C  CG1 . ILE C 1 225 ? -63.555 -30.243 24.439  1.00 33.10  ? 204 ILE C CG1 1 
ATOM   8012  C  CG2 . ILE C 1 225 ? -63.643 -31.571 26.597  1.00 33.37  ? 204 ILE C CG2 1 
ATOM   8013  C  CD1 . ILE C 1 225 ? -64.800 -31.018 23.947  1.00 32.27  ? 204 ILE C CD1 1 
ATOM   8014  N  N   . THR C 1 226 ? -63.369 -28.657 28.750  1.00 37.09  ? 205 THR C N   1 
ATOM   8015  C  CA  . THR C 1 226 ? -63.312 -28.645 30.212  1.00 42.53  ? 205 THR C CA  1 
ATOM   8016  C  C   . THR C 1 226 ? -64.523 -27.928 30.803  1.00 39.03  ? 205 THR C C   1 
ATOM   8017  O  O   . THR C 1 226 ? -65.151 -28.431 31.746  1.00 40.34  ? 205 THR C O   1 
ATOM   8018  C  CB  . THR C 1 226 ? -62.013 -27.984 30.684  1.00 37.63  ? 205 THR C CB  1 
ATOM   8019  O  OG1 . THR C 1 226 ? -60.904 -28.811 30.330  1.00 42.79  ? 205 THR C OG1 1 
ATOM   8020  C  CG2 . THR C 1 226 ? -62.021 -27.808 32.202  1.00 50.55  ? 205 THR C CG2 1 
ATOM   8021  N  N   . ASP C 1 227 ? -64.876 -26.768 30.248  1.00 36.07  ? 206 ASP C N   1 
ATOM   8022  C  CA  . ASP C 1 227 ? -66.044 -26.024 30.719  1.00 40.90  ? 206 ASP C CA  1 
ATOM   8023  C  C   . ASP C 1 227 ? -67.329 -26.831 30.613  1.00 45.42  ? 206 ASP C C   1 
ATOM   8024  O  O   . ASP C 1 227 ? -68.232 -26.652 31.438  1.00 43.11  ? 206 ASP C O   1 
ATOM   8025  C  CB  . ASP C 1 227 ? -66.203 -24.722 29.941  1.00 39.28  ? 206 ASP C CB  1 
ATOM   8026  C  CG  . ASP C 1 227 ? -65.293 -23.623 30.457  1.00 50.32  ? 206 ASP C CG  1 
ATOM   8027  O  OD1 . ASP C 1 227 ? -64.623 -23.846 31.491  1.00 52.16  ? 206 ASP C OD1 1 
ATOM   8028  O  OD2 . ASP C 1 227 ? -65.233 -22.548 29.823  1.00 50.41  ? 206 ASP C OD2 1 
ATOM   8029  N  N   . VAL C 1 228 ? -67.449 -27.700 29.602  1.00 41.08  ? 207 VAL C N   1 
ATOM   8030  C  CA  . VAL C 1 228 ? -68.645 -28.533 29.498  1.00 43.21  ? 207 VAL C CA  1 
ATOM   8031  C  C   . VAL C 1 228 ? -68.582 -29.687 30.497  1.00 42.33  ? 207 VAL C C   1 
ATOM   8032  O  O   . VAL C 1 228 ? -69.589 -30.045 31.125  1.00 41.49  ? 207 VAL C O   1 
ATOM   8033  C  CB  . VAL C 1 228 ? -68.831 -29.043 28.051  1.00 38.26  ? 207 VAL C CB  1 
ATOM   8034  C  CG1 . VAL C 1 228 ? -70.007 -30.038 27.968  1.00 34.14  ? 207 VAL C CG1 1 
ATOM   8035  C  CG2 . VAL C 1 228 ? -69.041 -27.877 27.073  1.00 32.23  ? 207 VAL C CG2 1 
ATOM   8036  N  N   . ARG C 1 229 ? -67.406 -30.300 30.652  1.00 35.10  ? 208 ARG C N   1 
ATOM   8037  C  CA  . ARG C 1 229 ? -67.281 -31.407 31.592  1.00 36.84  ? 208 ARG C CA  1 
ATOM   8038  C  C   . ARG C 1 229 ? -67.490 -30.953 33.034  1.00 43.59  ? 208 ARG C C   1 
ATOM   8039  O  O   . ARG C 1 229 ? -67.961 -31.736 33.864  1.00 44.70  ? 208 ARG C O   1 
ATOM   8040  C  CB  . ARG C 1 229 ? -65.919 -32.063 31.419  1.00 37.03  ? 208 ARG C CB  1 
ATOM   8041  C  CG  . ARG C 1 229 ? -65.808 -32.788 30.089  1.00 37.31  ? 208 ARG C CG  1 
ATOM   8042  C  CD  . ARG C 1 229 ? -64.429 -33.401 29.911  1.00 31.11  ? 208 ARG C CD  1 
ATOM   8043  N  NE  . ARG C 1 229 ? -64.385 -34.258 28.733  1.00 34.94  ? 208 ARG C NE  1 
ATOM   8044  C  CZ  . ARG C 1 229 ? -63.344 -34.999 28.389  1.00 37.20  ? 208 ARG C CZ  1 
ATOM   8045  N  NH1 . ARG C 1 229 ? -62.223 -34.987 29.093  1.00 39.02  ? 208 ARG C NH1 1 
ATOM   8046  N  NH2 . ARG C 1 229 ? -63.434 -35.786 27.320  1.00 37.60  ? 208 ARG C NH2 1 
ATOM   8047  N  N   . GLU C 1 230 ? -67.174 -29.697 33.343  1.00 40.31  ? 209 GLU C N   1 
ATOM   8048  C  CA  . GLU C 1 230 ? -67.275 -29.179 34.698  1.00 49.14  ? 209 GLU C CA  1 
ATOM   8049  C  C   . GLU C 1 230 ? -68.587 -28.457 34.959  1.00 52.22  ? 209 GLU C C   1 
ATOM   8050  O  O   . GLU C 1 230 ? -68.783 -27.934 36.058  1.00 58.01  ? 209 GLU C O   1 
ATOM   8051  C  CB  . GLU C 1 230 ? -66.091 -28.253 34.996  1.00 42.11  ? 209 GLU C CB  1 
ATOM   8052  C  CG  . GLU C 1 230 ? -64.776 -29.029 35.154  1.00 49.00  ? 209 GLU C CG  1 
ATOM   8053  C  CD  . GLU C 1 230 ? -63.584 -28.125 35.412  1.00 67.20  ? 209 GLU C CD  1 
ATOM   8054  O  OE1 . GLU C 1 230 ? -63.777 -26.891 35.467  1.00 58.97  ? 209 GLU C OE1 1 
ATOM   8055  O  OE2 . GLU C 1 230 ? -62.455 -28.649 35.556  1.00 75.91  ? 209 GLU C OE2 1 
ATOM   8056  N  N   . GLY C 1 231 ? -69.489 -28.429 33.985  1.00 40.97  ? 210 GLY C N   1 
ATOM   8057  C  CA  . GLY C 1 231 ? -70.791 -27.829 34.154  1.00 47.86  ? 210 GLY C CA  1 
ATOM   8058  C  C   . GLY C 1 231 ? -70.874 -26.334 33.942  1.00 44.03  ? 210 GLY C C   1 
ATOM   8059  O  O   . GLY C 1 231 ? -71.981 -25.788 34.001  1.00 49.01  ? 210 GLY C O   1 
ATOM   8060  N  N   . ARG C 1 232 ? -69.754 -25.646 33.682  1.00 46.35  ? 211 ARG C N   1 
ATOM   8061  C  CA  . ARG C 1 232 ? -69.818 -24.192 33.519  1.00 33.62  ? 211 ARG C CA  1 
ATOM   8062  C  C   . ARG C 1 232 ? -70.487 -23.774 32.208  1.00 44.62  ? 211 ARG C C   1 
ATOM   8063  O  O   . ARG C 1 232 ? -70.997 -22.654 32.108  1.00 47.66  ? 211 ARG C O   1 
ATOM   8064  C  CB  . ARG C 1 232 ? -68.419 -23.590 33.607  1.00 47.61  ? 211 ARG C CB  1 
ATOM   8065  C  CG  . ARG C 1 232 ? -67.901 -23.512 35.028  1.00 61.24  ? 211 ARG C CG  1 
ATOM   8066  C  CD  . ARG C 1 232 ? -66.638 -22.693 35.108  1.00 58.22  ? 211 ARG C CD  1 
ATOM   8067  N  NE  . ARG C 1 232 ? -65.574 -23.329 34.350  1.00 64.91  ? 211 ARG C NE  1 
ATOM   8068  C  CZ  . ARG C 1 232 ? -64.801 -24.292 34.828  1.00 62.82  ? 211 ARG C CZ  1 
ATOM   8069  N  NH1 . ARG C 1 232 ? -64.933 -24.728 36.069  1.00 67.43  ? 211 ARG C NH1 1 
ATOM   8070  N  NH2 . ARG C 1 232 ? -63.874 -24.832 34.041  1.00 58.94  ? 211 ARG C NH2 1 
ATOM   8071  N  N   . ILE C 1 233 ? -70.470 -24.637 31.191  1.00 46.34  ? 212 ILE C N   1 
ATOM   8072  C  CA  . ILE C 1 233 ? -71.161 -24.425 29.923  1.00 42.76  ? 212 ILE C CA  1 
ATOM   8073  C  C   . ILE C 1 233 ? -72.057 -25.630 29.697  1.00 38.48  ? 212 ILE C C   1 
ATOM   8074  O  O   . ILE C 1 233 ? -71.611 -26.769 29.860  1.00 42.80  ? 212 ILE C O   1 
ATOM   8075  C  CB  . ILE C 1 233 ? -70.175 -24.274 28.742  1.00 42.13  ? 212 ILE C CB  1 
ATOM   8076  C  CG1 . ILE C 1 233 ? -69.414 -22.955 28.839  1.00 49.81  ? 212 ILE C CG1 1 
ATOM   8077  C  CG2 . ILE C 1 233 ? -70.914 -24.345 27.410  1.00 38.20  ? 212 ILE C CG2 1 
ATOM   8078  C  CD1 . ILE C 1 233 ? -68.456 -22.742 27.707  1.00 54.00  ? 212 ILE C CD1 1 
ATOM   8079  N  N   . THR C 1 234 ? -73.305 -25.390 29.313  1.00 43.59  ? 213 THR C N   1 
ATOM   8080  C  CA  . THR C 1 234 ? -74.236 -26.471 29.018  1.00 45.04  ? 213 THR C CA  1 
ATOM   8081  C  C   . THR C 1 234 ? -74.345 -26.598 27.505  1.00 36.56  ? 213 THR C C   1 
ATOM   8082  O  O   . THR C 1 234 ? -74.869 -25.703 26.842  1.00 41.01  ? 213 THR C O   1 
ATOM   8083  C  CB  . THR C 1 234 ? -75.603 -26.224 29.657  1.00 54.12  ? 213 THR C CB  1 
ATOM   8084  O  OG1 . THR C 1 234 ? -75.446 -26.041 31.074  1.00 49.99  ? 213 THR C OG1 1 
ATOM   8085  C  CG2 . THR C 1 234 ? -76.506 -27.429 29.424  1.00 44.23  ? 213 THR C CG2 1 
ATOM   8086  N  N   . ALA C 1 235 ? -73.830 -27.696 26.961  1.00 45.04  ? 214 ALA C N   1 
ATOM   8087  C  CA  . ALA C 1 235 ? -73.992 -27.969 25.537  1.00 41.09  ? 214 ALA C CA  1 
ATOM   8088  C  C   . ALA C 1 235 ? -75.421 -28.419 25.250  1.00 46.82  ? 214 ALA C C   1 
ATOM   8089  O  O   . ALA C 1 235 ? -76.042 -29.095 26.073  1.00 46.20  ? 214 ALA C O   1 
ATOM   8090  C  CB  . ALA C 1 235 ? -73.002 -29.046 25.087  1.00 35.97  ? 214 ALA C CB  1 
ATOM   8091  N  N   . ARG C 1 236 ? -75.945 -28.016 24.086  1.00 46.42  ? 215 ARG C N   1 
ATOM   8092  C  CA  . ARG C 1 236 ? -77.203 -28.553 23.580  1.00 44.10  ? 215 ARG C CA  1 
ATOM   8093  C  C   . ARG C 1 236 ? -77.197 -30.076 23.693  1.00 42.65  ? 215 ARG C C   1 
ATOM   8094  O  O   . ARG C 1 236 ? -76.214 -30.717 23.295  1.00 44.56  ? 215 ARG C O   1 
ATOM   8095  C  CB  . ARG C 1 236 ? -77.398 -28.172 22.111  1.00 50.51  ? 215 ARG C CB  1 
ATOM   8096  C  CG  . ARG C 1 236 ? -78.352 -27.059 21.827  1.00 53.83  ? 215 ARG C CG  1 
ATOM   8097  C  CD  . ARG C 1 236 ? -78.869 -27.128 20.374  1.00 61.74  ? 215 ARG C CD  1 
ATOM   8098  N  NE  . ARG C 1 236 ? -77.839 -26.937 19.349  1.00 55.37  ? 215 ARG C NE  1 
ATOM   8099  C  CZ  . ARG C 1 236 ? -77.628 -27.768 18.334  1.00 59.57  ? 215 ARG C CZ  1 
ATOM   8100  N  NH1 . ARG C 1 236 ? -78.325 -28.888 18.199  1.00 63.10  ? 215 ARG C NH1 1 
ATOM   8101  N  NH2 . ARG C 1 236 ? -76.706 -27.463 17.422  1.00 41.78  ? 215 ARG C NH2 1 
ATOM   8102  N  N   . PRO C 1 237 ? -78.255 -30.692 24.212  1.00 53.64  ? 216 PRO C N   1 
ATOM   8103  C  CA  . PRO C 1 237 ? -78.260 -32.158 24.294  1.00 42.52  ? 216 PRO C CA  1 
ATOM   8104  C  C   . PRO C 1 237 ? -78.162 -32.761 22.899  1.00 42.24  ? 216 PRO C C   1 
ATOM   8105  O  O   . PRO C 1 237 ? -78.766 -32.264 21.942  1.00 41.95  ? 216 PRO C O   1 
ATOM   8106  C  CB  . PRO C 1 237 ? -79.601 -32.477 24.969  1.00 44.37  ? 216 PRO C CB  1 
ATOM   8107  C  CG  . PRO C 1 237 ? -79.980 -31.204 25.676  1.00 44.97  ? 216 PRO C CG  1 
ATOM   8108  C  CD  . PRO C 1 237 ? -79.472 -30.097 24.786  1.00 52.48  ? 216 PRO C CD  1 
ATOM   8109  N  N   . ASP C 1 238 ? -77.320 -33.790 22.787  1.00 40.92  ? 217 ASP C N   1 
ATOM   8110  C  CA  . ASP C 1 238 ? -77.070 -34.585 21.589  1.00 43.30  ? 217 ASP C CA  1 
ATOM   8111  C  C   . ASP C 1 238 ? -76.223 -33.868 20.531  1.00 42.41  ? 217 ASP C C   1 
ATOM   8112  O  O   . ASP C 1 238 ? -76.012 -34.425 19.444  1.00 41.02  ? 217 ASP C O   1 
ATOM   8113  C  CB  . ASP C 1 238 ? -78.372 -35.072 20.950  1.00 36.72  ? 217 ASP C CB  1 
ATOM   8114  C  CG  . ASP C 1 238 ? -78.182 -36.350 20.165  1.00 41.38  ? 217 ASP C CG  1 
ATOM   8115  O  OD1 . ASP C 1 238 ? -77.225 -37.099 20.463  1.00 40.10  ? 217 ASP C OD1 1 
ATOM   8116  O  OD2 . ASP C 1 238 ? -78.972 -36.604 19.237  1.00 55.44  ? 217 ASP C OD2 1 
ATOM   8117  N  N   . CYS C 1 239 ? -75.701 -32.679 20.815  1.00 38.18  ? 218 CYS C N   1 
ATOM   8118  C  CA  . CYS C 1 239 ? -74.931 -31.967 19.798  1.00 38.91  ? 218 CYS C CA  1 
ATOM   8119  C  C   . CYS C 1 239 ? -73.489 -32.485 19.740  1.00 35.53  ? 218 CYS C C   1 
ATOM   8120  O  O   . CYS C 1 239 ? -73.027 -33.228 20.613  1.00 31.69  ? 218 CYS C O   1 
ATOM   8121  C  CB  . CYS C 1 239 ? -74.957 -30.461 20.060  1.00 34.38  ? 218 CYS C CB  1 
ATOM   8122  S  SG  . CYS C 1 239 ? -73.939 -29.800 21.434  1.00 35.47  ? 218 CYS C SG  1 
ATOM   8123  N  N   . VAL C 1 240 ? -72.780 -32.091 18.674  1.00 28.97  ? 219 VAL C N   1 
ATOM   8124  C  CA  . VAL C 1 240 ? -71.407 -32.552 18.463  1.00 26.08  ? 219 VAL C CA  1 
ATOM   8125  C  C   . VAL C 1 240 ? -70.535 -32.222 19.671  1.00 25.16  ? 219 VAL C C   1 
ATOM   8126  O  O   . VAL C 1 240 ? -69.784 -33.066 20.166  1.00 31.02  ? 219 VAL C O   1 
ATOM   8127  C  CB  . VAL C 1 240 ? -70.833 -31.934 17.179  1.00 25.68  ? 219 VAL C CB  1 
ATOM   8128  C  CG1 . VAL C 1 240 ? -69.351 -32.333 17.032  1.00 26.61  ? 219 VAL C CG1 1 
ATOM   8129  C  CG2 . VAL C 1 240 ? -71.675 -32.385 15.950  1.00 29.17  ? 219 VAL C CG2 1 
ATOM   8130  N  N   . LEU C 1 241 ? -70.641 -30.988 20.166  1.00 30.16  ? 220 LEU C N   1 
ATOM   8131  C  CA  . LEU C 1 241 ? -69.849 -30.553 21.313  1.00 33.56  ? 220 LEU C CA  1 
ATOM   8132  C  C   . LEU C 1 241 ? -70.056 -31.471 22.511  1.00 35.22  ? 220 LEU C C   1 
ATOM   8133  O  O   . LEU C 1 241 ? -69.093 -31.908 23.158  1.00 29.22  ? 220 LEU C O   1 
ATOM   8134  C  CB  . LEU C 1 241 ? -70.205 -29.102 21.670  1.00 30.78  ? 220 LEU C CB  1 
ATOM   8135  C  CG  . LEU C 1 241 ? -69.521 -28.499 22.916  1.00 30.13  ? 220 LEU C CG  1 
ATOM   8136  C  CD1 . LEU C 1 241 ? -68.005 -28.588 22.819  1.00 33.97  ? 220 LEU C CD1 1 
ATOM   8137  C  CD2 . LEU C 1 241 ? -69.939 -27.062 23.119  1.00 28.44  ? 220 LEU C CD2 1 
ATOM   8138  N  N   . GLU C 1 242 ? -71.309 -31.787 22.817  1.00 32.68  ? 221 GLU C N   1 
ATOM   8139  C  CA  . GLU C 1 242 ? -71.584 -32.705 23.911  1.00 31.16  ? 221 GLU C CA  1 
ATOM   8140  C  C   . GLU C 1 242 ? -70.920 -34.050 23.673  1.00 31.32  ? 221 GLU C C   1 
ATOM   8141  O  O   . GLU C 1 242 ? -70.257 -34.589 24.561  1.00 35.94  ? 221 GLU C O   1 
ATOM   8142  C  CB  . GLU C 1 242 ? -73.097 -32.862 24.072  1.00 35.35  ? 221 GLU C CB  1 
ATOM   8143  C  CG  . GLU C 1 242 ? -73.511 -33.736 25.252  1.00 51.93  ? 221 GLU C CG  1 
ATOM   8144  C  CD  . GLU C 1 242 ? -75.023 -33.745 25.453  1.00 68.88  ? 221 GLU C CD  1 
ATOM   8145  O  OE1 . GLU C 1 242 ? -75.721 -34.530 24.764  1.00 51.27  ? 221 GLU C OE1 1 
ATOM   8146  O  OE2 . GLU C 1 242 ? -75.509 -32.944 26.285  1.00 76.17  ? 221 GLU C OE2 1 
ATOM   8147  N  N   . HIS C 1 243 ? -71.053 -34.596 22.454  1.00 31.49  ? 222 HIS C N   1 
ATOM   8148  C  CA  . HIS C 1 243 ? -70.466 -35.901 22.172  1.00 30.98  ? 222 HIS C CA  1 
ATOM   8149  C  C   . HIS C 1 243 ? -68.944 -35.861 22.201  1.00 31.34  ? 222 HIS C C   1 
ATOM   8150  O  O   . HIS C 1 243 ? -68.313 -36.868 22.551  1.00 33.72  ? 222 HIS C O   1 
ATOM   8151  C  CB  . HIS C 1 243 ? -70.974 -36.442 20.833  1.00 28.29  ? 222 HIS C CB  1 
ATOM   8152  C  CG  . HIS C 1 243 ? -72.380 -36.960 20.890  1.00 30.72  ? 222 HIS C CG  1 
ATOM   8153  N  ND1 . HIS C 1 243 ? -72.679 -38.263 21.233  1.00 37.55  ? 222 HIS C ND1 1 
ATOM   8154  C  CD2 . HIS C 1 243 ? -73.568 -36.348 20.664  1.00 36.42  ? 222 HIS C CD2 1 
ATOM   8155  C  CE1 . HIS C 1 243 ? -73.989 -38.435 21.203  1.00 38.70  ? 222 HIS C CE1 1 
ATOM   8156  N  NE2 . HIS C 1 243 ? -74.553 -37.287 20.864  1.00 39.43  ? 222 HIS C NE2 1 
ATOM   8157  N  N   . MET C 1 244 ? -68.330 -34.714 21.887  1.00 29.16  ? 223 MET C N   1 
ATOM   8158  C  CA  . MET C 1 244 ? -66.874 -34.659 22.027  1.00 27.34  ? 223 MET C CA  1 
ATOM   8159  C  C   . MET C 1 244 ? -66.467 -34.529 23.491  1.00 33.33  ? 223 MET C C   1 
ATOM   8160  O  O   . MET C 1 244 ? -65.480 -35.135 23.919  1.00 32.84  ? 223 MET C O   1 
ATOM   8161  C  CB  . MET C 1 244 ? -66.298 -33.516 21.184  1.00 29.24  ? 223 MET C CB  1 
ATOM   8162  C  CG  . MET C 1 244 ? -66.376 -33.762 19.645  1.00 31.70  ? 223 MET C CG  1 
ATOM   8163  S  SD  . MET C 1 244 ? -65.518 -35.260 19.117  1.00 38.31  ? 223 MET C SD  1 
ATOM   8164  C  CE  . MET C 1 244 ? -66.862 -36.447 18.960  1.00 34.34  ? 223 MET C CE  1 
ATOM   8165  N  N   . ALA C 1 245 ? -67.227 -33.772 24.284  1.00 34.69  ? 224 ALA C N   1 
ATOM   8166  C  CA  . ALA C 1 245 ? -66.971 -33.762 25.722  1.00 39.53  ? 224 ALA C CA  1 
ATOM   8167  C  C   . ALA C 1 245 ? -67.127 -35.153 26.327  1.00 40.54  ? 224 ALA C C   1 
ATOM   8168  O  O   . ALA C 1 245 ? -66.455 -35.468 27.307  1.00 38.49  ? 224 ALA C O   1 
ATOM   8169  C  CB  . ALA C 1 245 ? -67.884 -32.758 26.420  1.00 33.89  ? 224 ALA C CB  1 
ATOM   8170  N  N   . GLN C 1 246 ? -67.946 -36.020 25.721  1.00 37.47  ? 225 GLN C N   1 
ATOM   8171  C  CA  . GLN C 1 246 ? -68.124 -37.395 26.184  1.00 38.46  ? 225 GLN C CA  1 
ATOM   8172  C  C   . GLN C 1 246 ? -67.236 -38.398 25.447  1.00 41.38  ? 225 GLN C C   1 
ATOM   8173  O  O   . GLN C 1 246 ? -67.449 -39.614 25.562  1.00 36.01  ? 225 GLN C O   1 
ATOM   8174  C  CB  . GLN C 1 246 ? -69.596 -37.795 26.067  1.00 37.29  ? 225 GLN C CB  1 
ATOM   8175  C  CG  . GLN C 1 246 ? -70.512 -36.819 26.803  1.00 39.11  ? 225 GLN C CG  1 
ATOM   8176  C  CD  . GLN C 1 246 ? -71.983 -37.177 26.696  1.00 53.41  ? 225 GLN C CD  1 
ATOM   8177  O  OE1 . GLN C 1 246 ? -72.815 -36.619 27.415  1.00 61.31  ? 225 GLN C OE1 1 
ATOM   8178  N  NE2 . GLN C 1 246 ? -72.313 -38.102 25.796  1.00 53.24  ? 225 GLN C NE2 1 
ATOM   8179  N  N   . LEU C 1 247 ? -66.223 -37.924 24.722  1.00 32.22  ? 226 LEU C N   1 
ATOM   8180  C  CA  . LEU C 1 247 ? -65.369 -38.826 23.957  1.00 33.21  ? 226 LEU C CA  1 
ATOM   8181  C  C   . LEU C 1 247 ? -64.658 -39.815 24.885  1.00 36.43  ? 226 LEU C C   1 
ATOM   8182  O  O   . LEU C 1 247 ? -64.030 -39.409 25.868  1.00 35.38  ? 226 LEU C O   1 
ATOM   8183  C  CB  . LEU C 1 247 ? -64.349 -38.001 23.166  1.00 31.53  ? 226 LEU C CB  1 
ATOM   8184  C  CG  . LEU C 1 247 ? -63.522 -38.752 22.124  1.00 39.77  ? 226 LEU C CG  1 
ATOM   8185  C  CD1 . LEU C 1 247 ? -64.430 -39.229 21.014  1.00 33.89  ? 226 LEU C CD1 1 
ATOM   8186  C  CD2 . LEU C 1 247 ? -62.406 -37.849 21.591  1.00 33.86  ? 226 LEU C CD2 1 
ATOM   8187  N  N   . THR C 1 248 ? -64.749 -41.110 24.562  1.00 34.79  ? 227 THR C N   1 
ATOM   8188  C  CA  . THR C 1 248 ? -64.148 -42.187 25.350  1.00 38.24  ? 227 THR C CA  1 
ATOM   8189  C  C   . THR C 1 248 ? -63.248 -43.056 24.486  1.00 39.91  ? 227 THR C C   1 
ATOM   8190  O  O   . THR C 1 248 ? -63.368 -43.080 23.263  1.00 40.23  ? 227 THR C O   1 
ATOM   8191  C  CB  . THR C 1 248 ? -65.204 -43.100 25.977  1.00 37.52  ? 227 THR C CB  1 
ATOM   8192  O  OG1 . THR C 1 248 ? -66.061 -43.581 24.934  1.00 41.00  ? 227 THR C OG1 1 
ATOM   8193  C  CG2 . THR C 1 248 ? -66.027 -42.343 27.004  1.00 36.83  ? 227 THR C CG2 1 
ATOM   8194  N  N   . ASP C 1 249 ? -62.363 -43.807 25.140  1.00 36.90  ? 228 ASP C N   1 
ATOM   8195  C  CA  . ASP C 1 249 ? -61.448 -44.691 24.446  1.00 35.72  ? 228 ASP C CA  1 
ATOM   8196  C  C   . ASP C 1 249 ? -61.942 -46.134 24.528  1.00 36.70  ? 228 ASP C C   1 
ATOM   8197  O  O   . ASP C 1 249 ? -63.014 -46.424 25.068  1.00 46.83  ? 228 ASP C O   1 
ATOM   8198  C  CB  . ASP C 1 249 ? -60.033 -44.559 25.014  1.00 46.31  ? 228 ASP C CB  1 
ATOM   8199  C  CG  . ASP C 1 249 ? -59.968 -44.823 26.524  1.00 57.11  ? 228 ASP C CG  1 
ATOM   8200  O  OD1 . ASP C 1 249 ? -60.654 -45.744 27.029  1.00 56.04  ? 228 ASP C OD1 1 
ATOM   8201  O  OD2 . ASP C 1 249 ? -59.207 -44.111 27.207  1.00 66.73  ? 228 ASP C OD2 1 
ATOM   8202  N  N   . ALA C 1 250 ? -61.131 -47.048 23.991  1.00 38.31  ? 229 ALA C N   1 
ATOM   8203  C  CA  . ALA C 1 250 ? -61.515 -48.452 23.895  1.00 52.79  ? 229 ALA C CA  1 
ATOM   8204  C  C   . ALA C 1 250 ? -61.770 -49.082 25.260  1.00 61.43  ? 229 ALA C C   1 
ATOM   8205  O  O   . ALA C 1 250 ? -62.502 -50.074 25.348  1.00 57.22  ? 229 ALA C O   1 
ATOM   8206  C  CB  . ALA C 1 250 ? -60.435 -49.229 23.148  1.00 45.84  ? 229 ALA C CB  1 
ATOM   8207  N  N   . SER C 1 251 ? -61.202 -48.517 26.321  1.00 58.93  ? 230 SER C N   1 
ATOM   8208  C  CA  . SER C 1 251 ? -61.422 -48.973 27.686  1.00 58.35  ? 230 SER C CA  1 
ATOM   8209  C  C   . SER C 1 251 ? -62.665 -48.373 28.326  1.00 60.95  ? 230 SER C C   1 
ATOM   8210  O  O   . SER C 1 251 ? -62.928 -48.645 29.500  1.00 59.84  ? 230 SER C O   1 
ATOM   8211  C  CB  . SER C 1 251 ? -60.200 -48.635 28.546  1.00 61.54  ? 230 SER C CB  1 
ATOM   8212  O  OG  . SER C 1 251 ? -59.018 -49.159 27.965  1.00 65.84  ? 230 SER C OG  1 
ATOM   8213  N  N   . GLY C 1 252 ? -63.422 -47.554 27.602  1.00 55.78  ? 231 GLY C N   1 
ATOM   8214  C  CA  . GLY C 1 252 ? -64.565 -46.878 28.169  1.00 41.11  ? 231 GLY C CA  1 
ATOM   8215  C  C   . GLY C 1 252 ? -64.256 -45.629 28.968  1.00 49.72  ? 231 GLY C C   1 
ATOM   8216  O  O   . GLY C 1 252 ? -65.196 -44.969 29.436  1.00 59.66  ? 231 GLY C O   1 
ATOM   8217  N  N   . GLU C 1 253 ? -62.985 -45.272 29.142  1.00 42.31  ? 232 GLU C N   1 
ATOM   8218  C  CA  . GLU C 1 253 ? -62.630 -44.086 29.914  1.00 51.24  ? 232 GLU C CA  1 
ATOM   8219  C  C   . GLU C 1 253 ? -62.641 -42.830 29.039  1.00 51.11  ? 232 GLU C C   1 
ATOM   8220  O  O   . GLU C 1 253 ? -62.423 -42.894 27.827  1.00 44.25  ? 232 GLU C O   1 
ATOM   8221  C  CB  . GLU C 1 253 ? -61.255 -44.261 30.561  1.00 59.36  ? 232 GLU C CB  1 
ATOM   8222  C  CG  . GLU C 1 253 ? -61.155 -45.462 31.512  1.00 80.66  ? 232 GLU C CG  1 
ATOM   8223  C  CD  . GLU C 1 253 ? -61.908 -45.253 32.831  1.00 91.90  ? 232 GLU C CD  1 
ATOM   8224  O  OE1 . GLU C 1 253 ? -61.941 -44.105 33.335  1.00 61.93  ? 232 GLU C OE1 1 
ATOM   8225  O  OE2 . GLU C 1 253 ? -62.469 -46.243 33.364  1.00 91.96  ? 232 GLU C OE2 1 
ATOM   8226  N  N   . ARG C 1 254 ? -62.895 -41.685 29.674  1.00 38.94  ? 233 ARG C N   1 
ATOM   8227  C  CA  . ARG C 1 254 ? -62.965 -40.417 28.961  1.00 43.82  ? 233 ARG C CA  1 
ATOM   8228  C  C   . ARG C 1 254 ? -61.596 -40.016 28.436  1.00 50.06  ? 233 ARG C C   1 
ATOM   8229  O  O   . ARG C 1 254 ? -60.594 -40.097 29.151  1.00 40.53  ? 233 ARG C O   1 
ATOM   8230  C  CB  . ARG C 1 254 ? -63.488 -39.312 29.872  1.00 55.65  ? 233 ARG C CB  1 
ATOM   8231  C  CG  . ARG C 1 254 ? -64.979 -39.303 30.037  1.00 52.89  ? 233 ARG C CG  1 
ATOM   8232  C  CD  . ARG C 1 254 ? -65.508 -37.912 29.856  1.00 55.54  ? 233 ARG C CD  1 
ATOM   8233  N  NE  . ARG C 1 254 ? -66.962 -37.934 29.816  1.00 62.32  ? 233 ARG C NE  1 
ATOM   8234  C  CZ  . ARG C 1 254 ? -67.744 -37.256 30.639  1.00 63.39  ? 233 ARG C CZ  1 
ATOM   8235  N  NH1 . ARG C 1 254 ? -67.240 -36.416 31.535  1.00 54.56  ? 233 ARG C NH1 1 
ATOM   8236  N  NH2 . ARG C 1 254 ? -69.062 -37.427 30.563  1.00 53.92  ? 233 ARG C NH2 1 
ATOM   8237  N  N   . VAL C 1 255 ? -61.569 -39.563 27.179  1.00 40.30  ? 234 VAL C N   1 
ATOM   8238  C  CA  . VAL C 1 255 ? -60.352 -39.054 26.572  1.00 37.89  ? 234 VAL C CA  1 
ATOM   8239  C  C   . VAL C 1 255 ? -60.006 -37.704 27.195  1.00 32.66  ? 234 VAL C C   1 
ATOM   8240  O  O   . VAL C 1 255 ? -60.886 -36.917 27.559  1.00 39.87  ? 234 VAL C O   1 
ATOM   8241  C  CB  . VAL C 1 255 ? -60.559 -38.953 25.047  1.00 42.58  ? 234 VAL C CB  1 
ATOM   8242  C  CG1 . VAL C 1 255 ? -59.403 -38.258 24.383  1.00 44.43  ? 234 VAL C CG1 1 
ATOM   8243  C  CG2 . VAL C 1 255 ? -60.751 -40.344 24.449  1.00 34.44  ? 234 VAL C CG2 1 
ATOM   8244  N  N   . ASP C 1 256 ? -58.712 -37.432 27.334  1.00 35.75  ? 235 ASP C N   1 
ATOM   8245  C  CA  . ASP C 1 256 ? -58.298 -36.184 27.963  1.00 36.00  ? 235 ASP C CA  1 
ATOM   8246  C  C   . ASP C 1 256 ? -58.847 -34.986 27.196  1.00 39.70  ? 235 ASP C C   1 
ATOM   8247  O  O   . ASP C 1 256 ? -59.068 -35.046 25.980  1.00 36.30  ? 235 ASP C O   1 
ATOM   8248  C  CB  . ASP C 1 256 ? -56.772 -36.110 28.057  1.00 41.74  ? 235 ASP C CB  1 
ATOM   8249  C  CG  . ASP C 1 256 ? -56.105 -35.967 26.705  1.00 44.08  ? 235 ASP C CG  1 
ATOM   8250  O  OD1 . ASP C 1 256 ? -56.093 -34.841 26.160  1.00 51.43  ? 235 ASP C OD1 1 
ATOM   8251  O  OD2 . ASP C 1 256 ? -55.582 -36.981 26.192  1.00 63.71  ? 235 ASP C OD2 1 
ATOM   8252  N  N   . ALA C 1 257 ? -59.050 -33.883 27.926  1.00 37.49  ? 236 ALA C N   1 
ATOM   8253  C  CA  . ALA C 1 257 ? -59.779 -32.739 27.385  1.00 31.51  ? 236 ALA C CA  1 
ATOM   8254  C  C   . ALA C 1 257 ? -59.078 -32.116 26.172  1.00 37.91  ? 236 ALA C C   1 
ATOM   8255  O  O   . ALA C 1 257 ? -59.742 -31.641 25.238  1.00 34.05  ? 236 ALA C O   1 
ATOM   8256  C  CB  . ALA C 1 257 ? -59.986 -31.684 28.477  1.00 36.69  ? 236 ALA C CB  1 
ATOM   8257  N  N   . ARG C 1 258 ? -57.746 -32.067 26.176  1.00 37.36  ? 237 ARG C N   1 
ATOM   8258  C  CA  . ARG C 1 258 ? -57.075 -31.455 25.032  1.00 34.20  ? 237 ARG C CA  1 
ATOM   8259  C  C   . ARG C 1 258 ? -57.285 -32.282 23.766  1.00 33.08  ? 237 ARG C C   1 
ATOM   8260  O  O   . ARG C 1 258 ? -57.538 -31.722 22.691  1.00 31.78  ? 237 ARG C O   1 
ATOM   8261  C  CB  . ARG C 1 258 ? -55.590 -31.275 25.306  1.00 30.70  ? 237 ARG C CB  1 
ATOM   8262  C  CG  . ARG C 1 258 ? -54.927 -30.281 24.340  1.00 38.59  ? 237 ARG C CG  1 
ATOM   8263  C  CD  . ARG C 1 258 ? -53.531 -29.910 24.814  1.00 43.55  ? 237 ARG C CD  1 
ATOM   8264  N  NE  . ARG C 1 258 ? -52.911 -28.893 23.970  1.00 33.53  ? 237 ARG C NE  1 
ATOM   8265  C  CZ  . ARG C 1 258 ? -52.998 -27.585 24.186  1.00 35.92  ? 237 ARG C CZ  1 
ATOM   8266  N  NH1 . ARG C 1 258 ? -53.716 -27.092 25.183  1.00 39.26  ? 237 ARG C NH1 1 
ATOM   8267  N  NH2 . ARG C 1 258 ? -52.351 -26.748 23.376  1.00 35.46  ? 237 ARG C NH2 1 
ATOM   8268  N  N   . THR C 1 259 ? -57.189 -33.608 23.880  1.00 31.60  ? 238 THR C N   1 
ATOM   8269  C  CA  . THR C 1 259 ? -57.456 -34.483 22.739  1.00 27.25  ? 238 THR C CA  1 
ATOM   8270  C  C   . THR C 1 259 ? -58.904 -34.371 22.284  1.00 30.95  ? 238 THR C C   1 
ATOM   8271  O  O   . THR C 1 259 ? -59.175 -34.306 21.080  1.00 29.91  ? 238 THR C O   1 
ATOM   8272  C  CB  . THR C 1 259 ? -57.119 -35.918 23.107  1.00 30.06  ? 238 THR C CB  1 
ATOM   8273  O  OG1 . THR C 1 259 ? -55.764 -35.978 23.553  1.00 34.48  ? 238 THR C OG1 1 
ATOM   8274  C  CG2 . THR C 1 259 ? -57.302 -36.866 21.917  1.00 34.55  ? 238 THR C CG2 1 
ATOM   8275  N  N   . ALA C 1 260 ? -59.852 -34.337 23.227  1.00 32.87  ? 239 ALA C N   1 
ATOM   8276  C  CA  . ALA C 1 260 ? -61.249 -34.160 22.838  1.00 31.10  ? 239 ALA C CA  1 
ATOM   8277  C  C   . ALA C 1 260 ? -61.458 -32.815 22.146  1.00 35.13  ? 239 ALA C C   1 
ATOM   8278  O  O   . ALA C 1 260 ? -62.259 -32.710 21.211  1.00 29.86  ? 239 ALA C O   1 
ATOM   8279  C  CB  . ALA C 1 260 ? -62.171 -34.282 24.058  1.00 31.03  ? 239 ALA C CB  1 
ATOM   8280  N  N   . GLY C 1 261 ? -60.732 -31.781 22.582  1.00 24.40  ? 240 GLY C N   1 
ATOM   8281  C  CA  . GLY C 1 261 ? -60.809 -30.493 21.901  1.00 24.44  ? 240 GLY C CA  1 
ATOM   8282  C  C   . GLY C 1 261 ? -60.205 -30.541 20.502  1.00 27.02  ? 240 GLY C C   1 
ATOM   8283  O  O   . GLY C 1 261 ? -60.719 -29.918 19.562  1.00 30.38  ? 240 GLY C O   1 
ATOM   8284  N  N   . ILE C 1 262 ? -59.112 -31.292 20.346  1.00 26.67  ? 241 ILE C N   1 
ATOM   8285  C  CA  . ILE C 1 262 ? -58.537 -31.528 19.020  1.00 29.48  ? 241 ILE C CA  1 
ATOM   8286  C  C   . ILE C 1 262 ? -59.546 -32.220 18.101  1.00 32.27  ? 241 ILE C C   1 
ATOM   8287  O  O   . ILE C 1 262 ? -59.700 -31.847 16.926  1.00 25.86  ? 241 ILE C O   1 
ATOM   8288  C  CB  . ILE C 1 262 ? -57.229 -32.328 19.197  1.00 29.16  ? 241 ILE C CB  1 
ATOM   8289  C  CG1 . ILE C 1 262 ? -56.116 -31.352 19.584  1.00 31.48  ? 241 ILE C CG1 1 
ATOM   8290  C  CG2 . ILE C 1 262 ? -56.860 -33.201 17.993  1.00 26.85  ? 241 ILE C CG2 1 
ATOM   8291  C  CD1 . ILE C 1 262 ? -54.968 -32.033 20.245  1.00 32.25  ? 241 ILE C CD1 1 
ATOM   8292  N  N   . GLU C 1 263 ? -60.283 -33.209 18.621  1.00 30.15  ? 242 GLU C N   1 
ATOM   8293  C  CA  . GLU C 1 263 ? -61.266 -33.891 17.774  1.00 28.33  ? 242 GLU C CA  1 
ATOM   8294  C  C   . GLU C 1 263 ? -62.491 -33.013 17.474  1.00 25.11  ? 242 GLU C C   1 
ATOM   8295  O  O   . GLU C 1 263 ? -63.072 -33.129 16.381  1.00 29.10  ? 242 GLU C O   1 
ATOM   8296  C  CB  . GLU C 1 263 ? -61.686 -35.231 18.403  1.00 26.67  ? 242 GLU C CB  1 
ATOM   8297  C  CG  . GLU C 1 263 ? -60.524 -36.213 18.614  1.00 30.06  ? 242 GLU C CG  1 
ATOM   8298  C  CD  . GLU C 1 263 ? -59.850 -36.697 17.291  1.00 28.60  ? 242 GLU C CD  1 
ATOM   8299  O  OE1 . GLU C 1 263 ? -59.903 -35.994 16.263  1.00 34.58  ? 242 GLU C OE1 1 
ATOM   8300  O  OE2 . GLU C 1 263 ? -59.238 -37.785 17.300  1.00 32.09  ? 242 GLU C OE2 1 
ATOM   8301  N  N   . LEU C 1 264 ? -62.875 -32.110 18.391  1.00 27.76  ? 243 LEU C N   1 
ATOM   8302  C  CA  . LEU C 1 264 ? -63.882 -31.107 18.054  1.00 27.07  ? 243 LEU C CA  1 
ATOM   8303  C  C   . LEU C 1 264 ? -63.432 -30.245 16.871  1.00 32.92  ? 243 LEU C C   1 
ATOM   8304  O  O   . LEU C 1 264 ? -64.223 -29.947 15.966  1.00 25.31  ? 243 LEU C O   1 
ATOM   8305  C  CB  . LEU C 1 264 ? -64.175 -30.225 19.274  1.00 24.58  ? 243 LEU C CB  1 
ATOM   8306  C  CG  . LEU C 1 264 ? -65.189 -29.104 19.045  1.00 30.20  ? 243 LEU C CG  1 
ATOM   8307  C  CD1 . LEU C 1 264 ? -66.581 -29.667 18.757  1.00 33.66  ? 243 LEU C CD1 1 
ATOM   8308  C  CD2 . LEU C 1 264 ? -65.242 -28.207 20.248  1.00 31.42  ? 243 LEU C CD2 1 
ATOM   8309  N  N   . GLN C 1 265 ? -62.160 -29.825 16.860  1.00 26.17  ? 244 GLN C N   1 
ATOM   8310  C  CA  . GLN C 1 265 ? -61.658 -29.092 15.702  1.00 31.13  ? 244 GLN C CA  1 
ATOM   8311  C  C   . GLN C 1 265 ? -61.637 -29.952 14.444  1.00 22.53  ? 244 GLN C C   1 
ATOM   8312  O  O   . GLN C 1 265 ? -61.802 -29.422 13.344  1.00 27.53  ? 244 GLN C O   1 
ATOM   8313  C  CB  . GLN C 1 265 ? -60.253 -28.568 15.959  1.00 27.81  ? 244 GLN C CB  1 
ATOM   8314  C  CG  . GLN C 1 265 ? -60.175 -27.554 17.071  1.00 27.13  ? 244 GLN C CG  1 
ATOM   8315  C  CD  . GLN C 1 265 ? -58.752 -27.298 17.411  1.00 27.16  ? 244 GLN C CD  1 
ATOM   8316  O  OE1 . GLN C 1 265 ? -58.033 -26.690 16.613  1.00 32.41  ? 244 GLN C OE1 1 
ATOM   8317  N  NE2 . GLN C 1 265 ? -58.298 -27.812 18.573  1.00 29.20  ? 244 GLN C NE2 1 
ATOM   8318  N  N   . ASN C 1 266 ? -61.420 -31.257 14.583  1.00 25.15  ? 245 ASN C N   1 
ATOM   8319  C  CA  . ASN C 1 266 ? -61.398 -32.155 13.431  1.00 23.37  ? 245 ASN C CA  1 
ATOM   8320  C  C   . ASN C 1 266 ? -62.797 -32.401 12.886  1.00 25.75  ? 245 ASN C C   1 
ATOM   8321  O  O   . ASN C 1 266 ? -62.925 -33.069 11.858  1.00 26.26  ? 245 ASN C O   1 
ATOM   8322  C  CB  . ASN C 1 266 ? -60.708 -33.473 13.804  1.00 23.57  ? 245 ASN C CB  1 
ATOM   8323  C  CG  . ASN C 1 266 ? -59.175 -33.344 13.838  1.00 31.74  ? 245 ASN C CG  1 
ATOM   8324  O  OD1 . ASN C 1 266 ? -58.603 -32.500 13.138  1.00 29.59  ? 245 ASN C OD1 1 
ATOM   8325  N  ND2 . ASN C 1 266 ? -58.510 -34.186 14.636  1.00 28.62  ? 245 ASN C ND2 1 
ATOM   8326  N  N   . LEU C 1 267 ? -63.834 -31.842 13.520  1.00 25.90  ? 246 LEU C N   1 
ATOM   8327  C  CA  . LEU C 1 267 ? -65.204 -31.883 13.006  1.00 27.75  ? 246 LEU C CA  1 
ATOM   8328  C  C   . LEU C 1 267 ? -65.717 -30.503 12.628  1.00 30.32  ? 246 LEU C C   1 
ATOM   8329  O  O   . LEU C 1 267 ? -66.913 -30.356 12.345  1.00 27.67  ? 246 LEU C O   1 
ATOM   8330  C  CB  . LEU C 1 267 ? -66.156 -32.538 14.025  1.00 27.79  ? 246 LEU C CB  1 
ATOM   8331  C  CG  . LEU C 1 267 ? -65.841 -34.001 14.330  1.00 32.22  ? 246 LEU C CG  1 
ATOM   8332  C  CD1 . LEU C 1 267 ? -66.715 -34.573 15.462  1.00 29.04  ? 246 LEU C CD1 1 
ATOM   8333  C  CD2 . LEU C 1 267 ? -65.948 -34.860 13.063  1.00 28.82  ? 246 LEU C CD2 1 
ATOM   8334  N  N   . THR C 1 268 ? -64.837 -29.489 12.591  1.00 25.96  ? 247 THR C N   1 
ATOM   8335  C  CA  . THR C 1 268 ? -65.219 -28.125 12.251  1.00 20.76  ? 247 THR C CA  1 
ATOM   8336  C  C   . THR C 1 268 ? -64.228 -27.468 11.285  1.00 24.86  ? 247 THR C C   1 
ATOM   8337  O  O   . THR C 1 268 ? -64.639 -26.903 10.269  1.00 25.26  ? 247 THR C O   1 
ATOM   8338  C  CB  . THR C 1 268 ? -65.344 -27.271 13.520  1.00 27.74  ? 247 THR C CB  1 
ATOM   8339  O  OG1 . THR C 1 268 ? -64.240 -27.540 14.392  1.00 30.77  ? 247 THR C OG1 1 
ATOM   8340  C  CG2 . THR C 1 268 ? -66.637 -27.590 14.264  1.00 25.52  ? 247 THR C CG2 1 
ATOM   8341  N  N   . ARG C 1 269 ? -62.934 -27.521 11.592  1.00 23.79  ? 248 ARG C N   1 
ATOM   8342  C  CA  . ARG C 1 269 ? -61.925 -26.995 10.670  1.00 23.02  ? 248 ARG C CA  1 
ATOM   8343  C  C   . ARG C 1 269 ? -62.021 -27.600 9.276   1.00 27.36  ? 248 ARG C C   1 
ATOM   8344  O  O   . ARG C 1 269 ? -61.920 -26.846 8.302   1.00 22.10  ? 248 ARG C O   1 
ATOM   8345  C  CB  . ARG C 1 269 ? -60.519 -27.201 11.274  1.00 22.24  ? 248 ARG C CB  1 
ATOM   8346  C  CG  . ARG C 1 269 ? -59.363 -26.647 10.384  1.00 24.61  ? 248 ARG C CG  1 
ATOM   8347  C  CD  . ARG C 1 269 ? -58.036 -27.428 10.571  1.00 24.42  ? 248 ARG C CD  1 
ATOM   8348  N  NE  . ARG C 1 269 ? -58.185 -28.853 10.284  1.00 26.24  ? 248 ARG C NE  1 
ATOM   8349  C  CZ  . ARG C 1 269 ? -58.281 -29.807 11.209  1.00 26.09  ? 248 ARG C CZ  1 
ATOM   8350  N  NH1 . ARG C 1 269 ? -58.229 -29.531 12.511  1.00 24.18  ? 248 ARG C NH1 1 
ATOM   8351  N  NH2 . ARG C 1 269 ? -58.421 -31.075 10.824  1.00 27.41  ? 248 ARG C NH2 1 
ATOM   8352  N  N   . PRO C 1 270 ? -62.257 -28.897 9.090   1.00 21.82  ? 249 PRO C N   1 
ATOM   8353  C  CA  . PRO C 1 270 ? -62.327 -29.404 7.711   1.00 22.60  ? 249 PRO C CA  1 
ATOM   8354  C  C   . PRO C 1 270 ? -63.514 -28.860 6.939   1.00 23.17  ? 249 PRO C C   1 
ATOM   8355  O  O   . PRO C 1 270 ? -63.454 -28.775 5.710   1.00 24.42  ? 249 PRO C O   1 
ATOM   8356  C  CB  . PRO C 1 270 ? -62.408 -30.924 7.900   1.00 26.10  ? 249 PRO C CB  1 
ATOM   8357  C  CG  . PRO C 1 270 ? -61.808 -31.178 9.253   1.00 25.82  ? 249 PRO C CG  1 
ATOM   8358  C  CD  . PRO C 1 270 ? -62.220 -29.986 10.075  1.00 23.70  ? 249 PRO C CD  1 
ATOM   8359  N  N   . THR C 1 271 ? -64.578 -28.442 7.620   1.00 21.91  ? 250 THR C N   1 
ATOM   8360  C  CA  . THR C 1 271 ? -65.670 -27.766 6.930   1.00 21.23  ? 250 THR C CA  1 
ATOM   8361  C  C   . THR C 1 271 ? -65.223 -26.414 6.411   1.00 26.26  ? 250 THR C C   1 
ATOM   8362  O  O   . THR C 1 271 ? -65.543 -26.053 5.270   1.00 24.48  ? 250 THR C O   1 
ATOM   8363  C  CB  . THR C 1 271 ? -66.887 -27.655 7.862   1.00 23.19  ? 250 THR C CB  1 
ATOM   8364  O  OG1 . THR C 1 271 ? -67.206 -28.981 8.297   1.00 24.71  ? 250 THR C OG1 1 
ATOM   8365  C  CG2 . THR C 1 271 ? -68.092 -27.085 7.114   1.00 21.58  ? 250 THR C CG2 1 
ATOM   8366  N  N   . VAL C 1 272 ? -64.452 -25.663 7.220   1.00 22.35  ? 251 VAL C N   1 
ATOM   8367  C  CA  . VAL C 1 272 ? -63.837 -24.422 6.736   1.00 22.18  ? 251 VAL C CA  1 
ATOM   8368  C  C   . VAL C 1 272 ? -63.013 -24.688 5.472   1.00 21.68  ? 251 VAL C C   1 
ATOM   8369  O  O   . VAL C 1 272 ? -63.021 -23.892 4.517   1.00 25.10  ? 251 VAL C O   1 
ATOM   8370  C  CB  . VAL C 1 272 ? -62.971 -23.797 7.849   1.00 22.65  ? 251 VAL C CB  1 
ATOM   8371  C  CG1 . VAL C 1 272 ? -62.240 -22.541 7.355   1.00 20.26  ? 251 VAL C CG1 1 
ATOM   8372  C  CG2 . VAL C 1 272 ? -63.818 -23.486 9.101   1.00 26.20  ? 251 VAL C CG2 1 
ATOM   8373  N  N   . ALA C 1 273 ? -62.286 -25.806 5.459   1.00 20.35  ? 252 ALA C N   1 
ATOM   8374  C  CA  . ALA C 1 273 ? -61.394 -26.128 4.344   1.00 24.42  ? 252 ALA C CA  1 
ATOM   8375  C  C   . ALA C 1 273 ? -62.160 -26.355 3.034   1.00 23.42  ? 252 ALA C C   1 
ATOM   8376  O  O   . ALA C 1 273 ? -61.558 -26.290 1.958   1.00 20.14  ? 252 ALA C O   1 
ATOM   8377  C  CB  . ALA C 1 273 ? -60.558 -27.372 4.690   1.00 22.33  ? 252 ALA C CB  1 
ATOM   8378  N  N   . VAL C 1 274 ? -63.483 -26.560 3.081   1.00 20.85  ? 253 VAL C N   1 
ATOM   8379  C  CA  . VAL C 1 274 ? -64.205 -26.605 1.804   1.00 20.51  ? 253 VAL C CA  1 
ATOM   8380  C  C   . VAL C 1 274 ? -64.059 -25.299 1.033   1.00 22.16  ? 253 VAL C C   1 
ATOM   8381  O  O   . VAL C 1 274 ? -64.269 -25.279 -0.178  1.00 21.84  ? 253 VAL C O   1 
ATOM   8382  C  CB  . VAL C 1 274 ? -65.701 -26.965 2.034   1.00 23.36  ? 253 VAL C CB  1 
ATOM   8383  C  CG1 . VAL C 1 274 ? -66.464 -27.072 0.708   1.00 23.34  ? 253 VAL C CG1 1 
ATOM   8384  C  CG2 . VAL C 1 274 ? -65.772 -28.281 2.778   1.00 22.08  ? 253 VAL C CG2 1 
ATOM   8385  N  N   . GLY C 1 275 ? -63.644 -24.215 1.692   1.00 20.10  ? 254 GLY C N   1 
ATOM   8386  C  CA  . GLY C 1 275 ? -63.433 -22.968 0.983   1.00 22.04  ? 254 GLY C CA  1 
ATOM   8387  C  C   . GLY C 1 275 ? -62.430 -23.085 -0.164  1.00 22.48  ? 254 GLY C C   1 
ATOM   8388  O  O   . GLY C 1 275 ? -62.521 -22.350 -1.143  1.00 21.46  ? 254 GLY C O   1 
ATOM   8389  N  N   . PHE C 1 276 ? -61.452 -23.985 -0.054  1.00 21.67  ? 255 PHE C N   1 
ATOM   8390  C  CA  . PHE C 1 276 ? -60.556 -24.226 -1.198  1.00 21.39  ? 255 PHE C CA  1 
ATOM   8391  C  C   . PHE C 1 276 ? -61.322 -24.758 -2.414  1.00 22.67  ? 255 PHE C C   1 
ATOM   8392  O  O   . PHE C 1 276 ? -61.162 -24.260 -3.544  1.00 23.29  ? 255 PHE C O   1 
ATOM   8393  C  CB  . PHE C 1 276 ? -59.442 -25.195 -0.794  1.00 18.77  ? 255 PHE C CB  1 
ATOM   8394  C  CG  . PHE C 1 276 ? -58.427 -24.581 0.128   1.00 23.13  ? 255 PHE C CG  1 
ATOM   8395  C  CD1 . PHE C 1 276 ? -58.585 -24.655 1.509   1.00 24.35  ? 255 PHE C CD1 1 
ATOM   8396  C  CD2 . PHE C 1 276 ? -57.289 -23.958 -0.391  1.00 22.98  ? 255 PHE C CD2 1 
ATOM   8397  C  CE1 . PHE C 1 276 ? -57.645 -24.065 2.372   1.00 25.71  ? 255 PHE C CE1 1 
ATOM   8398  C  CE2 . PHE C 1 276 ? -56.333 -23.388 0.469   1.00 26.41  ? 255 PHE C CE2 1 
ATOM   8399  C  CZ  . PHE C 1 276 ? -56.521 -23.441 1.844   1.00 22.03  ? 255 PHE C CZ  1 
ATOM   8400  N  N   . PHE C 1 277 ? -62.163 -25.768 -2.208  1.00 19.27  ? 256 PHE C N   1 
ATOM   8401  C  CA  . PHE C 1 277 ? -62.986 -26.258 -3.317  1.00 25.53  ? 256 PHE C CA  1 
ATOM   8402  C  C   . PHE C 1 277 ? -63.960 -25.186 -3.808  1.00 22.32  ? 256 PHE C C   1 
ATOM   8403  O  O   . PHE C 1 277 ? -64.238 -25.109 -5.012  1.00 22.10  ? 256 PHE C O   1 
ATOM   8404  C  CB  . PHE C 1 277 ? -63.761 -27.522 -2.907  1.00 20.93  ? 256 PHE C CB  1 
ATOM   8405  C  CG  . PHE C 1 277 ? -62.961 -28.810 -2.993  1.00 22.34  ? 256 PHE C CG  1 
ATOM   8406  C  CD1 . PHE C 1 277 ? -62.100 -29.061 -4.053  1.00 26.11  ? 256 PHE C CD1 1 
ATOM   8407  C  CD2 . PHE C 1 277 ? -63.146 -29.797 -2.034  1.00 26.47  ? 256 PHE C CD2 1 
ATOM   8408  C  CE1 . PHE C 1 277 ? -61.409 -30.260 -4.141  1.00 23.37  ? 256 PHE C CE1 1 
ATOM   8409  C  CE2 . PHE C 1 277 ? -62.463 -30.994 -2.106  1.00 23.35  ? 256 PHE C CE2 1 
ATOM   8410  C  CZ  . PHE C 1 277 ? -61.587 -31.217 -3.175  1.00 23.43  ? 256 PHE C CZ  1 
ATOM   8411  N  N   . ALA C 1 278 ? -64.495 -24.361 -2.895  1.00 22.63  ? 257 ALA C N   1 
ATOM   8412  C  CA  . ALA C 1 278 ? -65.401 -23.299 -3.321  1.00 21.80  ? 257 ALA C CA  1 
ATOM   8413  C  C   . ALA C 1 278 ? -64.688 -22.289 -4.240  1.00 22.21  ? 257 ALA C C   1 
ATOM   8414  O  O   . ALA C 1 278 ? -65.275 -21.822 -5.226  1.00 22.81  ? 257 ALA C O   1 
ATOM   8415  C  CB  . ALA C 1 278 ? -66.015 -22.597 -2.098  1.00 22.45  ? 257 ALA C CB  1 
ATOM   8416  N  N   . SER C 1 279 ? -63.430 -21.939 -3.924  1.00 23.49  ? 258 SER C N   1 
ATOM   8417  C  CA  . SER C 1 279 ? -62.633 -21.096 -4.824  1.00 21.97  ? 258 SER C CA  1 
ATOM   8418  C  C   . SER C 1 279 ? -62.493 -21.736 -6.189  1.00 23.42  ? 258 SER C C   1 
ATOM   8419  O  O   . SER C 1 279 ? -62.727 -21.093 -7.215  1.00 22.85  ? 258 SER C O   1 
ATOM   8420  C  CB  . SER C 1 279 ? -61.222 -20.838 -4.245  1.00 23.28  ? 258 SER C CB  1 
ATOM   8421  O  OG  . SER C 1 279 ? -61.343 -20.392 -2.926  1.00 43.66  ? 258 SER C OG  1 
ATOM   8422  N  N   . PHE C 1 280 ? -62.130 -23.020 -6.223  1.00 21.52  ? 259 PHE C N   1 
ATOM   8423  C  CA  . PHE C 1 280 ? -62.024 -23.701 -7.517  1.00 21.88  ? 259 PHE C CA  1 
ATOM   8424  C  C   . PHE C 1 280 ? -63.380 -23.762 -8.235  1.00 23.89  ? 259 PHE C C   1 
ATOM   8425  O  O   . PHE C 1 280 ? -63.438 -23.723 -9.472  1.00 22.83  ? 259 PHE C O   1 
ATOM   8426  C  CB  . PHE C 1 280 ? -61.476 -25.118 -7.321  1.00 21.80  ? 259 PHE C CB  1 
ATOM   8427  C  CG  . PHE C 1 280 ? -59.966 -25.168 -7.020  1.00 22.31  ? 259 PHE C CG  1 
ATOM   8428  C  CD1 . PHE C 1 280 ? -59.050 -24.539 -7.855  1.00 22.38  ? 259 PHE C CD1 1 
ATOM   8429  C  CD2 . PHE C 1 280 ? -59.506 -25.836 -5.890  1.00 25.76  ? 259 PHE C CD2 1 
ATOM   8430  C  CE1 . PHE C 1 280 ? -57.659 -24.615 -7.579  1.00 23.33  ? 259 PHE C CE1 1 
ATOM   8431  C  CE2 . PHE C 1 280 ? -58.159 -25.920 -5.604  1.00 29.98  ? 259 PHE C CE2 1 
ATOM   8432  C  CZ  . PHE C 1 280 ? -57.233 -25.291 -6.439  1.00 27.72  ? 259 PHE C CZ  1 
ATOM   8433  N  N   . ALA C 1 281 ? -64.478 -23.928 -7.482  1.00 22.92  ? 260 ALA C N   1 
ATOM   8434  C  CA  . ALA C 1 281 ? -65.774 -23.991 -8.150  1.00 19.29  ? 260 ALA C CA  1 
ATOM   8435  C  C   . ALA C 1 281 ? -66.094 -22.660 -8.830  1.00 21.18  ? 260 ALA C C   1 
ATOM   8436  O  O   . ALA C 1 281 ? -66.746 -22.633 -9.869  1.00 20.47  ? 260 ALA C O   1 
ATOM   8437  C  CB  . ALA C 1 281 ? -66.867 -24.361 -7.133  1.00 20.23  ? 260 ALA C CB  1 
ATOM   8438  N  N   . ALA C 1 282 ? -65.659 -21.530 -8.249  1.00 20.99  ? 261 ALA C N   1 
ATOM   8439  C  CA  . ALA C 1 282 ? -65.913 -20.242 -8.887  1.00 19.99  ? 261 ALA C CA  1 
ATOM   8440  C  C   . ALA C 1 282 ? -65.127 -20.129 -10.192 1.00 21.75  ? 261 ALA C C   1 
ATOM   8441  O  O   . ALA C 1 282 ? -65.650 -19.639 -11.196 1.00 22.57  ? 261 ALA C O   1 
ATOM   8442  C  CB  . ALA C 1 282 ? -65.564 -19.092 -7.915  1.00 22.97  ? 261 ALA C CB  1 
ATOM   8443  N  N   . VAL C 1 283 ? -63.870 -20.597 -10.195 1.00 20.62  ? 262 VAL C N   1 
ATOM   8444  C  CA  . VAL C 1 283 ? -63.091 -20.646 -11.430 1.00 21.27  ? 262 VAL C CA  1 
ATOM   8445  C  C   . VAL C 1 283 ? -63.817 -21.497 -12.470 1.00 19.23  ? 262 VAL C C   1 
ATOM   8446  O  O   . VAL C 1 283 ? -63.934 -21.127 -13.644 1.00 24.04  ? 262 VAL C O   1 
ATOM   8447  C  CB  . VAL C 1 283 ? -61.685 -21.201 -11.135 1.00 23.90  ? 262 VAL C CB  1 
ATOM   8448  C  CG1 . VAL C 1 283 ? -60.936 -21.509 -12.441 1.00 25.23  ? 262 VAL C CG1 1 
ATOM   8449  C  CG2 . VAL C 1 283 ? -60.881 -20.160 -10.284 1.00 24.08  ? 262 VAL C CG2 1 
ATOM   8450  N  N   . ALA C 1 284 ? -64.259 -22.685 -12.052 1.00 21.36  ? 263 ALA C N   1 
ATOM   8451  C  CA  . ALA C 1 284 ? -64.925 -23.610 -12.958 1.00 18.72  ? 263 ALA C CA  1 
ATOM   8452  C  C   . ALA C 1 284 ? -66.205 -23.007 -13.541 1.00 20.19  ? 263 ALA C C   1 
ATOM   8453  O  O   . ALA C 1 284 ? -66.530 -23.251 -14.708 1.00 24.17  ? 263 ALA C O   1 
ATOM   8454  C  CB  . ALA C 1 284 ? -65.249 -24.919 -12.226 1.00 19.26  ? 263 ALA C CB  1 
ATOM   8455  N  N   . LEU C 1 285 ? -66.952 -22.251 -12.742 1.00 22.78  ? 264 LEU C N   1 
ATOM   8456  C  CA  . LEU C 1 285 ? -68.172 -21.644 -13.268 1.00 21.80  ? 264 LEU C CA  1 
ATOM   8457  C  C   . LEU C 1 285 ? -67.847 -20.553 -14.280 1.00 23.96  ? 264 LEU C C   1 
ATOM   8458  O  O   . LEU C 1 285 ? -68.541 -20.425 -15.297 1.00 24.30  ? 264 LEU C O   1 
ATOM   8459  C  CB  . LEU C 1 285 ? -69.032 -21.095 -12.135 1.00 21.30  ? 264 LEU C CB  1 
ATOM   8460  C  CG  . LEU C 1 285 ? -69.729 -22.209 -11.324 1.00 26.79  ? 264 LEU C CG  1 
ATOM   8461  C  CD1 . LEU C 1 285 ? -70.146 -21.619 -9.952  1.00 23.60  ? 264 LEU C CD1 1 
ATOM   8462  C  CD2 . LEU C 1 285 ? -70.951 -22.811 -12.094 1.00 22.05  ? 264 LEU C CD2 1 
ATOM   8463  N  N   . ALA C 1 286 ? -66.769 -19.788 -14.039 1.00 23.81  ? 265 ALA C N   1 
ATOM   8464  C  CA  . ALA C 1 286 ? -66.314 -18.813 -15.030 1.00 23.59  ? 265 ALA C CA  1 
ATOM   8465  C  C   . ALA C 1 286 ? -65.875 -19.506 -16.306 1.00 25.01  ? 265 ALA C C   1 
ATOM   8466  O  O   . ALA C 1 286 ? -66.058 -18.972 -17.400 1.00 25.42  ? 265 ALA C O   1 
ATOM   8467  C  CB  . ALA C 1 286 ? -65.152 -17.979 -14.477 1.00 21.60  ? 265 ALA C CB  1 
ATOM   8468  N  N   . GLU C 1 287 ? -65.294 -20.695 -16.185 1.00 22.21  ? 266 GLU C N   1 
ATOM   8469  C  CA  . GLU C 1 287 ? -64.794 -21.415 -17.345 1.00 24.78  ? 266 GLU C CA  1 
ATOM   8470  C  C   . GLU C 1 287 ? -65.857 -22.241 -18.042 1.00 25.60  ? 266 GLU C C   1 
ATOM   8471  O  O   . GLU C 1 287 ? -65.604 -22.713 -19.157 1.00 25.89  ? 266 GLU C O   1 
ATOM   8472  C  CB  . GLU C 1 287 ? -63.635 -22.329 -16.951 1.00 24.64  ? 266 GLU C CB  1 
ATOM   8473  C  CG  . GLU C 1 287 ? -62.394 -21.513 -16.527 1.00 24.64  ? 266 GLU C CG  1 
ATOM   8474  C  CD  . GLU C 1 287 ? -61.234 -22.363 -16.096 1.00 35.42  ? 266 GLU C CD  1 
ATOM   8475  O  OE1 . GLU C 1 287 ? -61.443 -23.557 -15.761 1.00 40.51  ? 266 GLU C OE1 1 
ATOM   8476  O  OE2 . GLU C 1 287 ? -60.112 -21.810 -16.050 1.00 38.11  ? 266 GLU C OE2 1 
ATOM   8477  N  N   . ASN C 1 288 ? -67.016 -22.443 -17.423 1.00 24.14  ? 267 ASN C N   1 
ATOM   8478  C  CA  . ASN C 1 288 ? -68.036 -23.351 -17.952 1.00 26.75  ? 267 ASN C CA  1 
ATOM   8479  C  C   . ASN C 1 288 ? -69.392 -22.660 -17.926 1.00 26.69  ? 267 ASN C C   1 
ATOM   8480  O  O   . ASN C 1 288 ? -70.291 -23.034 -17.163 1.00 23.51  ? 267 ASN C O   1 
ATOM   8481  C  CB  . ASN C 1 288 ? -68.045 -24.659 -17.154 1.00 24.40  ? 267 ASN C CB  1 
ATOM   8482  C  CG  . ASN C 1 288 ? -66.779 -25.440 -17.349 1.00 28.18  ? 267 ASN C CG  1 
ATOM   8483  O  OD1 . ASN C 1 288 ? -66.650 -26.192 -18.322 1.00 33.88  ? 267 ASN C OD1 1 
ATOM   8484  N  ND2 . ASN C 1 288 ? -65.808 -25.259 -16.443 1.00 22.52  ? 267 ASN C ND2 1 
ATOM   8485  N  N   . PRO C 1 289 ? -69.575 -21.638 -18.769 1.00 27.54  ? 268 PRO C N   1 
ATOM   8486  C  CA  . PRO C 1 289 ? -70.813 -20.851 -18.689 1.00 27.46  ? 268 PRO C CA  1 
ATOM   8487  C  C   . PRO C 1 289 ? -72.070 -21.650 -19.005 1.00 27.12  ? 268 PRO C C   1 
ATOM   8488  O  O   . PRO C 1 289 ? -73.113 -21.339 -18.437 1.00 29.20  ? 268 PRO C O   1 
ATOM   8489  C  CB  . PRO C 1 289 ? -70.592 -19.716 -19.704 1.00 26.74  ? 268 PRO C CB  1 
ATOM   8490  C  CG  . PRO C 1 289 ? -69.422 -20.162 -20.561 1.00 28.75  ? 268 PRO C CG  1 
ATOM   8491  C  CD  . PRO C 1 289 ? -68.617 -21.118 -19.770 1.00 29.22  ? 268 PRO C CD  1 
ATOM   8492  N  N   . GLN C 1 290 ? -72.013 -22.674 -19.864 1.00 27.34  ? 269 GLN C N   1 
ATOM   8493  C  CA  . GLN C 1 290 ? -73.230 -23.449 -20.138 1.00 27.10  ? 269 GLN C CA  1 
ATOM   8494  C  C   . GLN C 1 290 ? -73.661 -24.266 -18.917 1.00 35.27  ? 269 GLN C C   1 
ATOM   8495  O  O   . GLN C 1 290 ? -74.859 -24.369 -18.623 1.00 26.01  ? 269 GLN C O   1 
ATOM   8496  C  CB  . GLN C 1 290 ? -73.014 -24.345 -21.356 1.00 32.73  ? 269 GLN C CB  1 
ATOM   8497  C  CG  . GLN C 1 290 ? -74.258 -25.094 -21.796 1.00 66.23  ? 269 GLN C CG  1 
ATOM   8498  C  CD  . GLN C 1 290 ? -73.977 -26.114 -22.894 1.00 88.72  ? 269 GLN C CD  1 
ATOM   8499  O  OE1 . GLN C 1 290 ? -72.901 -26.122 -23.506 1.00 83.64  ? 269 GLN C OE1 1 
ATOM   8500  N  NE2 . GLN C 1 290 ? -74.949 -26.989 -23.140 1.00 79.04  ? 269 GLN C NE2 1 
ATOM   8501  N  N   . TRP C 1 291 ? -72.705 -24.828 -18.170 1.00 24.58  ? 270 TRP C N   1 
ATOM   8502  C  CA  . TRP C 1 291 ? -73.063 -25.498 -16.915 1.00 25.90  ? 270 TRP C CA  1 
ATOM   8503  C  C   . TRP C 1 291 ? -73.652 -24.509 -15.926 1.00 26.77  ? 270 TRP C C   1 
ATOM   8504  O  O   . TRP C 1 291 ? -74.601 -24.811 -15.190 1.00 25.88  ? 270 TRP C O   1 
ATOM   8505  C  CB  . TRP C 1 291 ? -71.829 -26.204 -16.313 1.00 23.56  ? 270 TRP C CB  1 
ATOM   8506  C  CG  . TRP C 1 291 ? -71.675 -27.536 -16.869 1.00 23.63  ? 270 TRP C CG  1 
ATOM   8507  C  CD1 . TRP C 1 291 ? -70.804 -27.929 -17.851 1.00 28.85  ? 270 TRP C CD1 1 
ATOM   8508  C  CD2 . TRP C 1 291 ? -72.473 -28.690 -16.551 1.00 25.39  ? 270 TRP C CD2 1 
ATOM   8509  N  NE1 . TRP C 1 291 ? -71.006 -29.259 -18.153 1.00 28.88  ? 270 TRP C NE1 1 
ATOM   8510  C  CE2 . TRP C 1 291 ? -72.022 -29.746 -17.362 1.00 31.61  ? 270 TRP C CE2 1 
ATOM   8511  C  CE3 . TRP C 1 291 ? -73.518 -28.926 -15.650 1.00 25.95  ? 270 TRP C CE3 1 
ATOM   8512  C  CZ2 . TRP C 1 291 ? -72.583 -31.033 -17.300 1.00 36.14  ? 270 TRP C CZ2 1 
ATOM   8513  C  CZ3 . TRP C 1 291 ? -74.068 -30.217 -15.574 1.00 26.06  ? 270 TRP C CZ3 1 
ATOM   8514  C  CH2 . TRP C 1 291 ? -73.608 -31.242 -16.408 1.00 31.45  ? 270 TRP C CH2 1 
ATOM   8515  N  N   . ARG C 1 292 ? -73.103 -23.308 -15.905 1.00 26.38  ? 271 ARG C N   1 
ATOM   8516  C  CA  . ARG C 1 292 ? -73.632 -22.285 -15.030 1.00 29.09  ? 271 ARG C CA  1 
ATOM   8517  C  C   . ARG C 1 292 ? -75.107 -22.034 -15.321 1.00 27.04  ? 271 ARG C C   1 
ATOM   8518  O  O   . ARG C 1 292 ? -75.937 -22.025 -14.405 1.00 28.52  ? 271 ARG C O   1 
ATOM   8519  C  CB  . ARG C 1 292 ? -72.763 -21.032 -15.189 1.00 29.20  ? 271 ARG C CB  1 
ATOM   8520  C  CG  . ARG C 1 292 ? -73.106 -19.970 -14.240 1.00 26.67  ? 271 ARG C CG  1 
ATOM   8521  C  CD  . ARG C 1 292 ? -72.037 -18.898 -14.297 1.00 25.90  ? 271 ARG C CD  1 
ATOM   8522  N  NE  . ARG C 1 292 ? -72.405 -17.868 -13.346 1.00 31.34  ? 271 ARG C NE  1 
ATOM   8523  C  CZ  . ARG C 1 292 ? -71.718 -16.754 -13.157 1.00 33.28  ? 271 ARG C CZ  1 
ATOM   8524  N  NH1 . ARG C 1 292 ? -70.626 -16.493 -13.862 1.00 27.84  ? 271 ARG C NH1 1 
ATOM   8525  N  NH2 . ARG C 1 292 ? -72.142 -15.881 -12.243 1.00 30.78  ? 271 ARG C NH2 1 
ATOM   8526  N  N   . THR C 1 293 ? -75.475 -21.937 -16.603 1.00 26.46  ? 272 THR C N   1 
ATOM   8527  C  CA  . THR C 1 293 ? -76.883 -21.745 -16.949 1.00 26.33  ? 272 THR C CA  1 
ATOM   8528  C  C   . THR C 1 293 ? -77.748 -22.949 -16.580 1.00 29.67  ? 272 THR C C   1 
ATOM   8529  O  O   . THR C 1 293 ? -78.869 -22.782 -16.081 1.00 31.49  ? 272 THR C O   1 
ATOM   8530  C  CB  . THR C 1 293 ? -77.035 -21.459 -18.443 1.00 30.59  ? 272 THR C CB  1 
ATOM   8531  O  OG1 . THR C 1 293 ? -76.284 -20.293 -18.776 1.00 33.86  ? 272 THR C OG1 1 
ATOM   8532  C  CG2 . THR C 1 293 ? -78.519 -21.228 -18.786 1.00 35.25  ? 272 THR C CG2 1 
ATOM   8533  N  N   . ARG C 1 294 ? -77.265 -24.165 -16.843 1.00 29.08  ? 273 ARG C N   1 
ATOM   8534  C  CA  . ARG C 1 294 ? -78.012 -25.352 -16.435 1.00 31.49  ? 273 ARG C CA  1 
ATOM   8535  C  C   . ARG C 1 294 ? -78.244 -25.385 -14.934 1.00 34.48  ? 273 ARG C C   1 
ATOM   8536  O  O   . ARG C 1 294 ? -79.307 -25.821 -14.476 1.00 31.73  ? 273 ARG C O   1 
ATOM   8537  C  CB  . ARG C 1 294 ? -77.275 -26.607 -16.870 1.00 24.04  ? 273 ARG C CB  1 
ATOM   8538  C  CG  . ARG C 1 294 ? -77.256 -26.771 -18.370 1.00 32.04  ? 273 ARG C CG  1 
ATOM   8539  C  CD  . ARG C 1 294 ? -76.473 -28.003 -18.732 1.00 32.43  ? 273 ARG C CD  1 
ATOM   8540  N  NE  . ARG C 1 294 ? -77.102 -29.230 -18.263 1.00 31.22  ? 273 ARG C NE  1 
ATOM   8541  C  CZ  . ARG C 1 294 ? -76.616 -30.435 -18.533 1.00 41.51  ? 273 ARG C CZ  1 
ATOM   8542  N  NH1 . ARG C 1 294 ? -75.477 -30.583 -19.192 1.00 32.75  ? 273 ARG C NH1 1 
ATOM   8543  N  NH2 . ARG C 1 294 ? -77.290 -31.517 -18.143 1.00 31.87  ? 273 ARG C NH2 1 
ATOM   8544  N  N   . ILE C 1 295 ? -77.268 -24.933 -14.144 1.00 27.80  ? 274 ILE C N   1 
ATOM   8545  C  CA  . ILE C 1 295 ? -77.460 -24.946 -12.696 1.00 22.71  ? 274 ILE C CA  1 
ATOM   8546  C  C   . ILE C 1 295 ? -78.516 -23.925 -12.295 1.00 29.55  ? 274 ILE C C   1 
ATOM   8547  O  O   . ILE C 1 295 ? -79.358 -24.187 -11.436 1.00 29.50  ? 274 ILE C O   1 
ATOM   8548  C  CB  . ILE C 1 295 ? -76.135 -24.691 -11.951 1.00 28.15  ? 274 ILE C CB  1 
ATOM   8549  C  CG1 . ILE C 1 295 ? -75.198 -25.891 -12.085 1.00 24.91  ? 274 ILE C CG1 1 
ATOM   8550  C  CG2 . ILE C 1 295 ? -76.408 -24.421 -10.461 1.00 28.28  ? 274 ILE C CG2 1 
ATOM   8551  C  CD1 . ILE C 1 295 ? -73.702 -25.521 -11.878 1.00 23.49  ? 274 ILE C CD1 1 
ATOM   8552  N  N   . ASN C 1 296 ? -78.485 -22.746 -12.914 1.00 29.79  ? 275 ASN C N   1 
ATOM   8553  C  CA  . ASN C 1 296 ? -79.434 -21.690 -12.572 1.00 32.84  ? 275 ASN C CA  1 
ATOM   8554  C  C   . ASN C 1 296 ? -80.860 -22.077 -12.917 1.00 33.69  ? 275 ASN C C   1 
ATOM   8555  O  O   . ASN C 1 296 ? -81.803 -21.659 -12.243 1.00 35.61  ? 275 ASN C O   1 
ATOM   8556  C  CB  . ASN C 1 296 ? -79.077 -20.418 -13.317 1.00 30.45  ? 275 ASN C CB  1 
ATOM   8557  C  CG  . ASN C 1 296 ? -77.908 -19.758 -12.730 1.00 33.55  ? 275 ASN C CG  1 
ATOM   8558  O  OD1 . ASN C 1 296 ? -77.714 -19.833 -11.523 1.00 37.51  ? 275 ASN C OD1 1 
ATOM   8559  N  ND2 . ASN C 1 296 ? -77.097 -19.097 -13.569 1.00 33.89  ? 275 ASN C ND2 1 
ATOM   8560  N  N   . GLU C 1 297 ? -81.039 -22.810 -13.998 1.00 32.15  ? 276 GLU C N   1 
ATOM   8561  C  CA  . GLU C 1 297 ? -82.390 -23.134 -14.436 1.00 36.35  ? 276 GLU C CA  1 
ATOM   8562  C  C   . GLU C 1 297 ? -82.947 -24.373 -13.749 1.00 42.40  ? 276 GLU C C   1 
ATOM   8563  O  O   . GLU C 1 297 ? -84.143 -24.658 -13.884 1.00 37.46  ? 276 GLU C O   1 
ATOM   8564  C  CB  . GLU C 1 297 ? -82.407 -23.325 -15.951 1.00 32.47  ? 276 GLU C CB  1 
ATOM   8565  C  CG  . GLU C 1 297 ? -81.998 -22.081 -16.711 1.00 40.16  ? 276 GLU C CG  1 
ATOM   8566  C  CD  . GLU C 1 297 ? -81.879 -22.326 -18.197 1.00 64.23  ? 276 GLU C CD  1 
ATOM   8567  O  OE1 . GLU C 1 297 ? -81.942 -23.510 -18.610 1.00 71.66  ? 276 GLU C OE1 1 
ATOM   8568  O  OE2 . GLU C 1 297 ? -81.724 -21.333 -18.947 1.00 67.30  ? 276 GLU C OE2 1 
ATOM   8569  N  N   . SER C 1 298 ? -82.122 -25.098 -13.004 1.00 33.28  ? 277 SER C N   1 
ATOM   8570  C  CA  . SER C 1 298 ? -82.530 -26.385 -12.455 1.00 34.91  ? 277 SER C CA  1 
ATOM   8571  C  C   . SER C 1 298 ? -83.456 -26.216 -11.260 1.00 33.38  ? 277 SER C C   1 
ATOM   8572  O  O   . SER C 1 298 ? -83.261 -25.338 -10.419 1.00 36.60  ? 277 SER C O   1 
ATOM   8573  C  CB  . SER C 1 298 ? -81.296 -27.186 -12.016 1.00 28.86  ? 277 SER C CB  1 
ATOM   8574  O  OG  . SER C 1 298 ? -81.680 -28.432 -11.440 1.00 32.39  ? 277 SER C OG  1 
ATOM   8575  N  N   . GLU C 1 299 ? -84.415 -27.126 -11.131 1.00 30.03  ? 278 GLU C N   1 
ATOM   8576  C  CA  . GLU C 1 299 ? -85.179 -27.232 -9.897  1.00 39.75  ? 278 GLU C CA  1 
ATOM   8577  C  C   . GLU C 1 299 ? -84.859 -28.497 -9.122  1.00 36.94  ? 278 GLU C C   1 
ATOM   8578  O  O   . GLU C 1 299 ? -85.562 -28.820 -8.165  1.00 40.44  ? 278 GLU C O   1 
ATOM   8579  C  CB  . GLU C 1 299 ? -86.675 -27.167 -10.202 1.00 43.98  ? 278 GLU C CB  1 
ATOM   8580  C  CG  . GLU C 1 299 ? -87.129 -25.809 -10.755 1.00 73.00  ? 278 GLU C CG  1 
ATOM   8581  C  CD  . GLU C 1 299 ? -87.992 -25.027 -9.774  1.00 87.20  ? 278 GLU C CD  1 
ATOM   8582  O  OE1 . GLU C 1 299 ? -89.228 -25.233 -9.772  1.00 100.68 ? 278 GLU C OE1 1 
ATOM   8583  O  OE2 . GLU C 1 299 ? -87.434 -24.216 -8.999  1.00 94.30  ? 278 GLU C OE2 1 
ATOM   8584  N  N   . THR C 1 300 ? -83.825 -29.239 -9.513  1.00 31.22  ? 279 THR C N   1 
ATOM   8585  C  CA  . THR C 1 300 ? -83.564 -30.529 -8.885  1.00 29.12  ? 279 THR C CA  1 
ATOM   8586  C  C   . THR C 1 300 ? -82.313 -30.552 -8.028  1.00 32.67  ? 279 THR C C   1 
ATOM   8587  O  O   . THR C 1 300 ? -82.172 -31.460 -7.210  1.00 32.44  ? 279 THR C O   1 
ATOM   8588  C  CB  . THR C 1 300 ? -83.410 -31.622 -9.942  1.00 31.22  ? 279 THR C CB  1 
ATOM   8589  O  OG1 . THR C 1 300 ? -82.221 -31.366 -10.722 1.00 30.29  ? 279 THR C OG1 1 
ATOM   8590  C  CG2 . THR C 1 300 ? -84.621 -31.631 -10.876 1.00 34.48  ? 279 THR C CG2 1 
ATOM   8591  N  N   . GLY C 1 301 ? -81.389 -29.619 -8.225  1.00 30.18  ? 280 GLY C N   1 
ATOM   8592  C  CA  . GLY C 1 301 ? -80.110 -29.702 -7.545  1.00 30.67  ? 280 GLY C CA  1 
ATOM   8593  C  C   . GLY C 1 301 ? -79.148 -30.723 -8.121  1.00 32.22  ? 280 GLY C C   1 
ATOM   8594  O  O   . GLY C 1 301 ? -78.014 -30.806 -7.646  1.00 26.29  ? 280 GLY C O   1 
ATOM   8595  N  N   . ARG C 1 302 ? -79.560 -31.507 -9.127  1.00 23.76  ? 281 ARG C N   1 
ATOM   8596  C  CA  . ARG C 1 302 ? -78.675 -32.553 -9.642  1.00 26.77  ? 281 ARG C CA  1 
ATOM   8597  C  C   . ARG C 1 302 ? -77.447 -31.969 -10.325 1.00 26.76  ? 281 ARG C C   1 
ATOM   8598  O  O   . ARG C 1 302 ? -76.337 -32.504 -10.157 1.00 23.02  ? 281 ARG C O   1 
ATOM   8599  C  CB  . ARG C 1 302 ? -79.416 -33.481 -10.619 1.00 26.15  ? 281 ARG C CB  1 
ATOM   8600  C  CG  . ARG C 1 302 ? -80.521 -34.312 -9.950  1.00 39.63  ? 281 ARG C CG  1 
ATOM   8601  C  CD  . ARG C 1 302 ? -79.976 -35.505 -9.123  1.00 46.36  ? 281 ARG C CD  1 
ATOM   8602  N  NE  . ARG C 1 302 ? -79.310 -36.524 -9.937  1.00 38.86  ? 281 ARG C NE  1 
ATOM   8603  C  CZ  . ARG C 1 302 ? -79.918 -37.556 -10.519 1.00 39.30  ? 281 ARG C CZ  1 
ATOM   8604  N  NH1 . ARG C 1 302 ? -81.230 -37.756 -10.405 1.00 39.75  ? 281 ARG C NH1 1 
ATOM   8605  N  NH2 . ARG C 1 302 ? -79.195 -38.402 -11.252 1.00 30.99  ? 281 ARG C NH2 1 
ATOM   8606  N  N   . GLU C 1 303 ? -77.630 -30.919 -11.145 1.00 23.87  ? 282 GLU C N   1 
ATOM   8607  C  CA  . GLU C 1 303 ? -76.501 -30.341 -11.874 1.00 24.73  ? 282 GLU C CA  1 
ATOM   8608  C  C   . GLU C 1 303 ? -75.499 -29.717 -10.903 1.00 23.59  ? 282 GLU C C   1 
ATOM   8609  O  O   . GLU C 1 303 ? -74.284 -29.858 -11.083 1.00 22.95  ? 282 GLU C O   1 
ATOM   8610  C  CB  . GLU C 1 303 ? -76.974 -29.280 -12.880 1.00 25.70  ? 282 GLU C CB  1 
ATOM   8611  C  CG  . GLU C 1 303 ? -77.916 -29.802 -14.003 1.00 27.05  ? 282 GLU C CG  1 
ATOM   8612  C  CD  . GLU C 1 303 ? -79.371 -30.037 -13.539 1.00 34.07  ? 282 GLU C CD  1 
ATOM   8613  O  OE1 . GLU C 1 303 ? -79.752 -29.696 -12.391 1.00 32.01  ? 282 GLU C OE1 1 
ATOM   8614  O  OE2 . GLU C 1 303 ? -80.131 -30.575 -14.353 1.00 33.16  ? 282 GLU C OE2 1 
ATOM   8615  N  N   . ALA C 1 304 ? -75.995 -29.035 -9.868  1.00 21.38  ? 283 ALA C N   1 
ATOM   8616  C  CA  . ALA C 1 304 ? -75.095 -28.466 -8.853  1.00 23.36  ? 283 ALA C CA  1 
ATOM   8617  C  C   . ALA C 1 304 ? -74.323 -29.563 -8.138  1.00 26.18  ? 283 ALA C C   1 
ATOM   8618  O  O   . ALA C 1 304 ? -73.113 -29.427 -7.878  1.00 24.01  ? 283 ALA C O   1 
ATOM   8619  C  CB  . ALA C 1 304 ? -75.888 -27.637 -7.838  1.00 24.07  ? 283 ALA C CB  1 
ATOM   8620  N  N   . PHE C 1 305 ? -75.015 -30.651 -7.787  1.00 22.73  ? 284 PHE C N   1 
ATOM   8621  C  CA  . PHE C 1 305 ? -74.351 -31.807 -7.177  1.00 23.25  ? 284 PHE C CA  1 
ATOM   8622  C  C   . PHE C 1 305 ? -73.264 -32.359 -8.089  1.00 20.52  ? 284 PHE C C   1 
ATOM   8623  O  O   . PHE C 1 305 ? -72.135 -32.605 -7.657  1.00 22.09  ? 284 PHE C O   1 
ATOM   8624  C  CB  . PHE C 1 305 ? -75.404 -32.878 -6.883  1.00 23.67  ? 284 PHE C CB  1 
ATOM   8625  C  CG  . PHE C 1 305 ? -74.841 -34.214 -6.443  1.00 29.23  ? 284 PHE C CG  1 
ATOM   8626  C  CD1 . PHE C 1 305 ? -74.532 -34.437 -5.112  1.00 29.42  ? 284 PHE C CD1 1 
ATOM   8627  C  CD2 . PHE C 1 305 ? -74.670 -35.249 -7.361  1.00 32.29  ? 284 PHE C CD2 1 
ATOM   8628  C  CE1 . PHE C 1 305 ? -74.043 -35.680 -4.674  1.00 28.04  ? 284 PHE C CE1 1 
ATOM   8629  C  CE2 . PHE C 1 305 ? -74.174 -36.503 -6.961  1.00 29.84  ? 284 PHE C CE2 1 
ATOM   8630  C  CZ  . PHE C 1 305 ? -73.865 -36.728 -5.615  1.00 24.81  ? 284 PHE C CZ  1 
ATOM   8631  N  N   . ALA C 1 306 ? -73.596 -32.583 -9.360  1.00 21.43  ? 285 ALA C N   1 
ATOM   8632  C  CA  . ALA C 1 306 ? -72.627 -33.175 -10.281 1.00 21.50  ? 285 ALA C CA  1 
ATOM   8633  C  C   . ALA C 1 306 ? -71.459 -32.232 -10.500 1.00 23.33  ? 285 ALA C C   1 
ATOM   8634  O  O   . ALA C 1 306 ? -70.310 -32.669 -10.620 1.00 21.37  ? 285 ALA C O   1 
ATOM   8635  C  CB  . ALA C 1 306 ? -73.291 -33.510 -11.620 1.00 19.65  ? 285 ALA C CB  1 
ATOM   8636  N  N   . PHE C 1 307 ? -71.738 -30.936 -10.540 1.00 22.03  ? 286 PHE C N   1 
ATOM   8637  C  CA  . PHE C 1 307 ? -70.684 -29.947 -10.752 1.00 24.50  ? 286 PHE C CA  1 
ATOM   8638  C  C   . PHE C 1 307 ? -69.755 -29.911 -9.543  1.00 23.48  ? 286 PHE C C   1 
ATOM   8639  O  O   . PHE C 1 307 ? -68.516 -29.837 -9.679  1.00 20.21  ? 286 PHE C O   1 
ATOM   8640  C  CB  . PHE C 1 307 ? -71.334 -28.575 -10.974 1.00 23.16  ? 286 PHE C CB  1 
ATOM   8641  C  CG  . PHE C 1 307 ? -70.395 -27.512 -11.486 1.00 22.15  ? 286 PHE C CG  1 
ATOM   8642  C  CD1 . PHE C 1 307 ? -69.569 -26.791 -10.601 1.00 19.12  ? 286 PHE C CD1 1 
ATOM   8643  C  CD2 . PHE C 1 307 ? -70.384 -27.181 -12.838 1.00 21.65  ? 286 PHE C CD2 1 
ATOM   8644  C  CE1 . PHE C 1 307 ? -68.739 -25.757 -11.105 1.00 22.19  ? 286 PHE C CE1 1 
ATOM   8645  C  CE2 . PHE C 1 307 ? -69.563 -26.175 -13.332 1.00 23.05  ? 286 PHE C CE2 1 
ATOM   8646  C  CZ  . PHE C 1 307 ? -68.741 -25.461 -12.470 1.00 24.63  ? 286 PHE C CZ  1 
ATOM   8647  N  N   . ALA C 1 308 ? -70.348 -29.962 -8.356  1.00 21.87  ? 287 ALA C N   1 
ATOM   8648  C  CA  . ALA C 1 308 ? -69.564 -29.988 -7.128  1.00 24.19  ? 287 ALA C CA  1 
ATOM   8649  C  C   . ALA C 1 308 ? -68.677 -31.225 -7.090  1.00 22.22  ? 287 ALA C C   1 
ATOM   8650  O  O   . ALA C 1 308 ? -67.517 -31.137 -6.705  1.00 21.49  ? 287 ALA C O   1 
ATOM   8651  C  CB  . ALA C 1 308 ? -70.482 -29.933 -5.897  1.00 20.31  ? 287 ALA C CB  1 
ATOM   8652  N  N   . GLN C 1 309 ? -69.200 -32.386 -7.500  1.00 21.57  ? 288 GLN C N   1 
ATOM   8653  C  CA  . GLN C 1 309 ? -68.391 -33.610 -7.479  1.00 19.92  ? 288 GLN C CA  1 
ATOM   8654  C  C   . GLN C 1 309 ? -67.246 -33.520 -8.477  1.00 21.58  ? 288 GLN C C   1 
ATOM   8655  O  O   . GLN C 1 309 ? -66.138 -33.976 -8.195  1.00 22.49  ? 288 GLN C O   1 
ATOM   8656  C  CB  . GLN C 1 309 ? -69.252 -34.852 -7.788  1.00 20.65  ? 288 GLN C CB  1 
ATOM   8657  C  CG  . GLN C 1 309 ? -70.311 -35.112 -6.685  1.00 24.98  ? 288 GLN C CG  1 
ATOM   8658  C  CD  . GLN C 1 309 ? -69.720 -35.708 -5.407  1.00 26.94  ? 288 GLN C CD  1 
ATOM   8659  O  OE1 . GLN C 1 309 ? -68.604 -35.367 -4.984  1.00 24.29  ? 288 GLN C OE1 1 
ATOM   8660  N  NE2 . GLN C 1 309 ? -70.476 -36.588 -4.773  1.00 25.32  ? 288 GLN C NE2 1 
ATOM   8661  N  N   . GLU C 1 310 ? -67.480 -32.911 -9.639  1.00 18.54  ? 289 GLU C N   1 
ATOM   8662  C  CA  . GLU C 1 310 ? -66.399 -32.845 -10.602 1.00 20.06  ? 289 GLU C CA  1 
ATOM   8663  C  C   . GLU C 1 310 ? -65.367 -31.775 -10.242 1.00 23.86  ? 289 GLU C C   1 
ATOM   8664  O  O   . GLU C 1 310 ? -64.213 -31.866 -10.679 1.00 24.40  ? 289 GLU C O   1 
ATOM   8665  C  CB  . GLU C 1 310 ? -66.978 -32.640 -12.021 1.00 28.18  ? 289 GLU C CB  1 
ATOM   8666  C  CG  . GLU C 1 310 ? -65.992 -32.447 -13.179 1.00 27.52  ? 289 GLU C CG  1 
ATOM   8667  C  CD  . GLU C 1 310 ? -65.180 -33.692 -13.549 1.00 27.84  ? 289 GLU C CD  1 
ATOM   8668  O  OE1 . GLU C 1 310 ? -65.027 -34.597 -12.697 1.00 39.71  ? 289 GLU C OE1 1 
ATOM   8669  O  OE2 . GLU C 1 310 ? -64.700 -33.780 -14.707 1.00 23.55  ? 289 GLU C OE2 1 
ATOM   8670  N  N   . VAL C 1 311 ? -65.731 -30.787 -9.436  1.00 20.75  ? 290 VAL C N   1 
ATOM   8671  C  CA  . VAL C 1 311 ? -64.715 -29.925 -8.831  1.00 19.82  ? 290 VAL C CA  1 
ATOM   8672  C  C   . VAL C 1 311 ? -63.805 -30.740 -7.915  1.00 19.56  ? 290 VAL C C   1 
ATOM   8673  O  O   . VAL C 1 311 ? -62.577 -30.590 -7.940  1.00 20.63  ? 290 VAL C O   1 
ATOM   8674  C  CB  . VAL C 1 311 ? -65.397 -28.768 -8.075  1.00 19.35  ? 290 VAL C CB  1 
ATOM   8675  C  CG1 . VAL C 1 311 ? -64.403 -28.046 -7.093  1.00 20.44  ? 290 VAL C CG1 1 
ATOM   8676  C  CG2 . VAL C 1 311 ? -66.006 -27.786 -9.091  1.00 20.40  ? 290 VAL C CG2 1 
ATOM   8677  N  N   . ARG C 1 312 ? -64.390 -31.604 -7.067  1.00 19.72  ? 291 ARG C N   1 
ATOM   8678  C  CA  . ARG C 1 312 ? -63.558 -32.419 -6.182  1.00 20.21  ? 291 ARG C CA  1 
ATOM   8679  C  C   . ARG C 1 312 ? -62.728 -33.418 -6.971  1.00 21.99  ? 291 ARG C C   1 
ATOM   8680  O  O   . ARG C 1 312 ? -61.612 -33.773 -6.560  1.00 23.39  ? 291 ARG C O   1 
ATOM   8681  C  CB  . ARG C 1 312 ? -64.425 -33.177 -5.153  1.00 20.66  ? 291 ARG C CB  1 
ATOM   8682  C  CG  . ARG C 1 312 ? -65.280 -32.228 -4.235  1.00 21.89  ? 291 ARG C CG  1 
ATOM   8683  C  CD  . ARG C 1 312 ? -65.696 -32.951 -2.928  1.00 22.66  ? 291 ARG C CD  1 
ATOM   8684  N  NE  . ARG C 1 312 ? -66.442 -34.180 -3.190  1.00 23.06  ? 291 ARG C NE  1 
ATOM   8685  C  CZ  . ARG C 1 312 ? -66.310 -35.315 -2.505  1.00 27.77  ? 291 ARG C CZ  1 
ATOM   8686  N  NH1 . ARG C 1 312 ? -65.499 -35.407 -1.463  1.00 26.83  ? 291 ARG C NH1 1 
ATOM   8687  N  NH2 . ARG C 1 312 ? -67.007 -36.392 -2.878  1.00 28.30  ? 291 ARG C NH2 1 
ATOM   8688  N  N   . ARG C 1 313 ? -63.257 -33.927 -8.082  1.00 20.10  ? 292 ARG C N   1 
ATOM   8689  C  CA  . ARG C 1 313 ? -62.424 -34.832 -8.858  1.00 19.87  ? 292 ARG C CA  1 
ATOM   8690  C  C   . ARG C 1 313 ? -61.280 -34.083 -9.527  1.00 25.95  ? 292 ARG C C   1 
ATOM   8691  O  O   . ARG C 1 313 ? -60.157 -34.594 -9.628  1.00 26.95  ? 292 ARG C O   1 
ATOM   8692  C  CB  . ARG C 1 313 ? -63.234 -35.565 -9.925  1.00 23.94  ? 292 ARG C CB  1 
ATOM   8693  C  CG  . ARG C 1 313 ? -62.358 -36.710 -10.478 1.00 32.09  ? 292 ARG C CG  1 
ATOM   8694  C  CD  . ARG C 1 313 ? -62.530 -37.070 -11.908 1.00 22.15  ? 292 ARG C CD  1 
ATOM   8695  N  NE  . ARG C 1 313 ? -62.566 -35.964 -12.855 1.00 21.01  ? 292 ARG C NE  1 
ATOM   8696  C  CZ  . ARG C 1 313 ? -61.622 -35.704 -13.745 1.00 22.67  ? 292 ARG C CZ  1 
ATOM   8697  N  NH1 . ARG C 1 313 ? -60.456 -36.350 -13.735 1.00 20.03  ? 292 ARG C NH1 1 
ATOM   8698  N  NH2 . ARG C 1 313 ? -61.850 -34.774 -14.675 1.00 23.16  ? 292 ARG C NH2 1 
ATOM   8699  N  N   . PHE C 1 314 ? -61.558 -32.895 -10.046 1.00 24.41  ? 293 PHE C N   1 
ATOM   8700  C  CA  . PHE C 1 314 ? -60.652 -32.331 -11.045 1.00 20.04  ? 293 PHE C CA  1 
ATOM   8701  C  C   . PHE C 1 314 ? -59.541 -31.495 -10.427 1.00 23.89  ? 293 PHE C C   1 
ATOM   8702  O  O   . PHE C 1 314 ? -58.409 -31.504 -10.939 1.00 25.91  ? 293 PHE C O   1 
ATOM   8703  C  CB  . PHE C 1 314 ? -61.457 -31.479 -12.032 1.00 25.56  ? 293 PHE C CB  1 
ATOM   8704  C  CG  . PHE C 1 314 ? -60.612 -30.825 -13.127 1.00 23.40  ? 293 PHE C CG  1 
ATOM   8705  C  CD1 . PHE C 1 314 ? -60.307 -31.513 -14.288 1.00 24.56  ? 293 PHE C CD1 1 
ATOM   8706  C  CD2 . PHE C 1 314 ? -60.138 -29.537 -12.976 1.00 25.70  ? 293 PHE C CD2 1 
ATOM   8707  C  CE1 . PHE C 1 314 ? -59.539 -30.917 -15.298 1.00 28.94  ? 293 PHE C CE1 1 
ATOM   8708  C  CE2 . PHE C 1 314 ? -59.358 -28.945 -13.977 1.00 32.84  ? 293 PHE C CE2 1 
ATOM   8709  C  CZ  . PHE C 1 314 ? -59.065 -29.641 -15.143 1.00 33.05  ? 293 PHE C CZ  1 
ATOM   8710  N  N   . TYR C 1 315 ? -59.873 -30.680 -9.387  1.00 20.61  ? 294 TYR C N   1 
ATOM   8711  C  CA  . TYR C 1 315 ? -58.933 -29.693 -8.886  1.00 21.31  ? 294 TYR C CA  1 
ATOM   8712  C  C   . TYR C 1 315 ? -58.079 -30.296 -7.774  1.00 23.32  ? 294 TYR C C   1 
ATOM   8713  O  O   . TYR C 1 315 ? -58.513 -31.218 -7.078  1.00 25.01  ? 294 TYR C O   1 
ATOM   8714  C  CB  . TYR C 1 315 ? -59.681 -28.442 -8.367  1.00 20.85  ? 294 TYR C CB  1 
ATOM   8715  C  CG  . TYR C 1 315 ? -60.273 -27.667 -9.528  1.00 22.97  ? 294 TYR C CG  1 
ATOM   8716  C  CD1 . TYR C 1 315 ? -59.468 -26.789 -10.272 1.00 21.94  ? 294 TYR C CD1 1 
ATOM   8717  C  CD2 . TYR C 1 315 ? -61.581 -27.885 -9.951  1.00 22.81  ? 294 TYR C CD2 1 
ATOM   8718  C  CE1 . TYR C 1 315 ? -59.971 -26.095 -11.384 1.00 22.34  ? 294 TYR C CE1 1 
ATOM   8719  C  CE2 . TYR C 1 315 ? -62.111 -27.173 -11.056 1.00 21.82  ? 294 TYR C CE2 1 
ATOM   8720  C  CZ  . TYR C 1 315 ? -61.291 -26.292 -11.758 1.00 24.13  ? 294 TYR C CZ  1 
ATOM   8721  O  OH  . TYR C 1 315 ? -61.766 -25.620 -12.876 1.00 28.56  ? 294 TYR C OH  1 
ATOM   8722  N  N   . PRO C 1 316 ? -56.846 -29.820 -7.621  1.00 22.97  ? 295 PRO C N   1 
ATOM   8723  C  CA  . PRO C 1 316 ? -55.939 -30.422 -6.636  1.00 20.90  ? 295 PRO C CA  1 
ATOM   8724  C  C   . PRO C 1 316 ? -56.297 -29.935 -5.244  1.00 22.48  ? 295 PRO C C   1 
ATOM   8725  O  O   . PRO C 1 316 ? -56.534 -28.740 -5.032  1.00 28.09  ? 295 PRO C O   1 
ATOM   8726  C  CB  . PRO C 1 316 ? -54.558 -29.893 -7.060  1.00 26.01  ? 295 PRO C CB  1 
ATOM   8727  C  CG  . PRO C 1 316 ? -54.895 -28.500 -7.621  1.00 22.88  ? 295 PRO C CG  1 
ATOM   8728  C  CD  . PRO C 1 316 ? -56.220 -28.718 -8.381  1.00 24.94  ? 295 PRO C CD  1 
ATOM   8729  N  N   . PHE C 1 317 ? -56.326 -30.869 -4.285  1.00 24.51  ? 296 PHE C N   1 
ATOM   8730  C  CA  . PHE C 1 317 ? -56.500 -30.496 -2.882  1.00 20.58  ? 296 PHE C CA  1 
ATOM   8731  C  C   . PHE C 1 317 ? -55.591 -31.396 -2.049  1.00 24.37  ? 296 PHE C C   1 
ATOM   8732  O  O   . PHE C 1 317 ? -54.534 -30.957 -1.583  1.00 22.90  ? 296 PHE C O   1 
ATOM   8733  C  CB  . PHE C 1 317 ? -57.986 -30.622 -2.473  1.00 24.35  ? 296 PHE C CB  1 
ATOM   8734  C  CG  . PHE C 1 317 ? -58.343 -29.940 -1.161  1.00 24.88  ? 296 PHE C CG  1 
ATOM   8735  C  CD1 . PHE C 1 317 ? -57.594 -30.136 -0.007  1.00 25.69  ? 296 PHE C CD1 1 
ATOM   8736  C  CD2 . PHE C 1 317 ? -59.495 -29.151 -1.075  1.00 27.99  ? 296 PHE C CD2 1 
ATOM   8737  C  CE1 . PHE C 1 317 ? -57.957 -29.489 1.200   1.00 27.09  ? 296 PHE C CE1 1 
ATOM   8738  C  CE2 . PHE C 1 317 ? -59.842 -28.514 0.085   1.00 29.40  ? 296 PHE C CE2 1 
ATOM   8739  C  CZ  . PHE C 1 317 ? -59.068 -28.681 1.238   1.00 27.16  ? 296 PHE C CZ  1 
ATOM   8740  N  N   . VAL C 1 318 ? -55.944 -32.670 -1.902  1.00 25.53  ? 297 VAL C N   1 
ATOM   8741  C  CA  . VAL C 1 318 ? -55.030 -33.616 -1.255  1.00 22.09  ? 297 VAL C CA  1 
ATOM   8742  C  C   . VAL C 1 318 ? -54.009 -34.038 -2.307  1.00 23.33  ? 297 VAL C C   1 
ATOM   8743  O  O   . VAL C 1 318 ? -54.395 -34.596 -3.338  1.00 25.63  ? 297 VAL C O   1 
ATOM   8744  C  CB  . VAL C 1 318 ? -55.756 -34.865 -0.724  1.00 25.34  ? 297 VAL C CB  1 
ATOM   8745  C  CG1 . VAL C 1 318 ? -54.743 -35.872 -0.131  1.00 25.61  ? 297 VAL C CG1 1 
ATOM   8746  C  CG2 . VAL C 1 318 ? -56.842 -34.477 0.265   1.00 22.53  ? 297 VAL C CG2 1 
ATOM   8747  N  N   . PRO C 1 319 ? -52.733 -33.817 -2.117  1.00 23.69  ? 298 PRO C N   1 
ATOM   8748  C  CA  . PRO C 1 319 ? -51.771 -34.274 -3.138  1.00 27.59  ? 298 PRO C CA  1 
ATOM   8749  C  C   . PRO C 1 319 ? -51.576 -35.785 -3.117  1.00 31.74  ? 298 PRO C C   1 
ATOM   8750  O  O   . PRO C 1 319 ? -51.604 -36.493 -4.148  1.00 25.95  ? 298 PRO C O   1 
ATOM   8751  C  CB  . PRO C 1 319 ? -50.482 -33.523 -2.762  1.00 25.96  ? 298 PRO C CB  1 
ATOM   8752  C  CG  . PRO C 1 319 ? -50.595 -33.248 -1.311  1.00 28.60  ? 298 PRO C CG  1 
ATOM   8753  C  CD  . PRO C 1 319 ? -52.088 -33.087 -1.005  1.00 25.49  ? 298 PRO C CD  1 
ATOM   8754  N  N   . MET C 1 320 ? -51.413 -36.285 -1.900  1.00 23.22  ? 299 MET C N   1 
ATOM   8755  C  CA  . MET C 1 320 ? -51.000 -37.654 -1.634  1.00 28.73  ? 299 MET C CA  1 
ATOM   8756  C  C   . MET C 1 320 ? -51.187 -37.871 -0.137  1.00 25.42  ? 299 MET C C   1 
ATOM   8757  O  O   . MET C 1 320 ? -51.432 -36.917 0.608   1.00 27.72  ? 299 MET C O   1 
ATOM   8758  C  CB  . MET C 1 320 ? -49.545 -37.869 -2.042  1.00 25.80  ? 299 MET C CB  1 
ATOM   8759  C  CG  . MET C 1 320 ? -48.590 -37.133 -1.117  1.00 28.08  ? 299 MET C CG  1 
ATOM   8760  S  SD  . MET C 1 320 ? -46.961 -37.051 -1.890  1.00 39.65  ? 299 MET C SD  1 
ATOM   8761  C  CE  . MET C 1 320 ? -47.147 -35.525 -2.861  1.00 31.02  ? 299 MET C CE  1 
ATOM   8762  N  N   . PHE C 1 321 ? -51.110 -39.139 0.298   1.00 25.04  ? 300 PHE C N   1 
ATOM   8763  C  CA  . PHE C 1 321 ? -51.328 -39.398 1.728   1.00 21.14  ? 300 PHE C CA  1 
ATOM   8764  C  C   . PHE C 1 321 ? -50.495 -40.603 2.135   1.00 22.26  ? 300 PHE C C   1 
ATOM   8765  O  O   . PHE C 1 321 ? -50.315 -41.516 1.319   1.00 25.92  ? 300 PHE C O   1 
ATOM   8766  C  CB  . PHE C 1 321 ? -52.803 -39.646 2.066   1.00 26.52  ? 300 PHE C CB  1 
ATOM   8767  C  CG  . PHE C 1 321 ? -53.239 -39.045 3.389   1.00 29.06  ? 300 PHE C CG  1 
ATOM   8768  C  CD1 . PHE C 1 321 ? -53.441 -37.674 3.515   1.00 25.54  ? 300 PHE C CD1 1 
ATOM   8769  C  CD2 . PHE C 1 321 ? -53.464 -39.847 4.495   1.00 27.13  ? 300 PHE C CD2 1 
ATOM   8770  C  CE1 . PHE C 1 321 ? -53.851 -37.100 4.729   1.00 26.97  ? 300 PHE C CE1 1 
ATOM   8771  C  CE2 . PHE C 1 321 ? -53.874 -39.275 5.733   1.00 21.94  ? 300 PHE C CE2 1 
ATOM   8772  C  CZ  . PHE C 1 321 ? -54.079 -37.913 5.832   1.00 28.44  ? 300 PHE C CZ  1 
ATOM   8773  N  N   . PRO C 1 322 ? -49.947 -40.631 3.401   1.00 28.07  ? 301 PRO C N   1 
ATOM   8774  C  CA  . PRO C 1 322 ? -49.018 -41.702 3.764   1.00 25.59  ? 301 PRO C CA  1 
ATOM   8775  C  C   . PRO C 1 322 ? -49.587 -42.715 4.755   1.00 27.63  ? 301 PRO C C   1 
ATOM   8776  O  O   . PRO C 1 322 ? -50.471 -42.410 5.576   1.00 25.36  ? 301 PRO C O   1 
ATOM   8777  C  CB  . PRO C 1 322 ? -47.839 -40.918 4.381   1.00 25.24  ? 301 PRO C CB  1 
ATOM   8778  C  CG  . PRO C 1 322 ? -48.524 -39.883 5.167   1.00 24.86  ? 301 PRO C CG  1 
ATOM   8779  C  CD  . PRO C 1 322 ? -49.765 -39.474 4.306   1.00 31.46  ? 301 PRO C CD  1 
ATOM   8780  N  N   . ALA C 1 323 ? -49.068 -43.941 4.636   1.00 25.17  ? 302 ALA C N   1 
ATOM   8781  C  CA  . ALA C 1 323 ? -49.202 -45.014 5.606   1.00 26.65  ? 302 ALA C CA  1 
ATOM   8782  C  C   . ALA C 1 323 ? -47.839 -45.693 5.736   1.00 30.65  ? 302 ALA C C   1 
ATOM   8783  O  O   . ALA C 1 323 ? -46.904 -45.396 4.981   1.00 27.93  ? 302 ALA C O   1 
ATOM   8784  C  CB  . ALA C 1 323 ? -50.285 -46.016 5.202   1.00 24.54  ? 302 ALA C CB  1 
ATOM   8785  N  N   . LYS C 1 324 ? -47.717 -46.616 6.707   1.00 27.96  ? 303 LYS C N   1 
ATOM   8786  C  CA  . LYS C 1 324 ? -46.504 -47.406 6.878   1.00 27.72  ? 303 LYS C CA  1 
ATOM   8787  C  C   . LYS C 1 324 ? -46.821 -48.895 6.840   1.00 26.83  ? 303 LYS C C   1 
ATOM   8788  O  O   . LYS C 1 324 ? -47.814 -49.343 7.422   1.00 27.28  ? 303 LYS C O   1 
ATOM   8789  C  CB  . LYS C 1 324 ? -45.775 -47.075 8.193   1.00 35.05  ? 303 LYS C CB  1 
ATOM   8790  C  CG  . LYS C 1 324 ? -44.923 -45.831 8.111   1.00 35.31  ? 303 LYS C CG  1 
ATOM   8791  C  CD  . LYS C 1 324 ? -44.237 -45.495 9.439   1.00 47.35  ? 303 LYS C CD  1 
ATOM   8792  C  CE  . LYS C 1 324 ? -43.327 -44.287 9.233   1.00 46.24  ? 303 LYS C CE  1 
ATOM   8793  N  NZ  . LYS C 1 324 ? -42.349 -44.101 10.347  1.00 57.33  ? 303 LYS C NZ  1 
ATOM   8794  N  N   . ALA C 1 325 ? -45.953 -49.657 6.172   1.00 30.22  ? 304 ALA C N   1 
ATOM   8795  C  CA  . ALA C 1 325 ? -46.097 -51.106 6.098   1.00 27.33  ? 304 ALA C CA  1 
ATOM   8796  C  C   . ALA C 1 325 ? -45.847 -51.735 7.470   1.00 31.15  ? 304 ALA C C   1 
ATOM   8797  O  O   . ALA C 1 325 ? -44.832 -51.438 8.106   1.00 31.37  ? 304 ALA C O   1 
ATOM   8798  C  CB  . ALA C 1 325 ? -45.107 -51.686 5.086   1.00 26.87  ? 304 ALA C CB  1 
ATOM   8799  N  N   . THR C 1 326 ? -46.758 -52.607 7.914   1.00 31.22  ? 305 THR C N   1 
ATOM   8800  C  CA  . THR C 1 326 ? -46.581 -53.344 9.174   1.00 33.45  ? 305 THR C CA  1 
ATOM   8801  C  C   . THR C 1 326 ? -45.874 -54.684 9.005   1.00 43.24  ? 305 THR C C   1 
ATOM   8802  O  O   . THR C 1 326 ? -45.503 -55.299 10.007  1.00 41.01  ? 305 THR C O   1 
ATOM   8803  C  CB  . THR C 1 326 ? -47.929 -53.621 9.838   1.00 32.25  ? 305 THR C CB  1 
ATOM   8804  O  OG1 . THR C 1 326 ? -48.655 -54.508 9.000   1.00 33.94  ? 305 THR C OG1 1 
ATOM   8805  C  CG2 . THR C 1 326 ? -48.712 -52.345 10.015  1.00 34.59  ? 305 THR C CG2 1 
ATOM   8806  N  N   . LYS C 1 327 ? -45.734 -55.175 7.783   1.00 31.89  ? 306 LYS C N   1 
ATOM   8807  C  CA  . LYS C 1 327 ? -45.021 -56.413 7.495   1.00 32.07  ? 306 LYS C CA  1 
ATOM   8808  C  C   . LYS C 1 327 ? -44.497 -56.298 6.082   1.00 48.81  ? 306 LYS C C   1 
ATOM   8809  O  O   . LYS C 1 327 ? -44.949 -55.449 5.310   1.00 37.94  ? 306 LYS C O   1 
ATOM   8810  C  CB  . LYS C 1 327 ? -45.919 -57.663 7.622   1.00 35.95  ? 306 LYS C CB  1 
ATOM   8811  C  CG  . LYS C 1 327 ? -47.139 -57.650 6.713   1.00 43.14  ? 306 LYS C CG  1 
ATOM   8812  C  CD  . LYS C 1 327 ? -47.610 -59.050 6.303   1.00 46.36  ? 306 LYS C CD  1 
ATOM   8813  C  CE  . LYS C 1 327 ? -48.202 -59.812 7.462   1.00 51.61  ? 306 LYS C CE  1 
ATOM   8814  N  NZ  . LYS C 1 327 ? -49.572 -59.346 7.767   1.00 53.19  ? 306 LYS C NZ  1 
ATOM   8815  N  N   . ASP C 1 328 ? -43.522 -57.142 5.756   1.00 40.72  ? 307 ASP C N   1 
ATOM   8816  C  CA  . ASP C 1 328 ? -43.093 -57.255 4.378   1.00 35.56  ? 307 ASP C CA  1 
ATOM   8817  C  C   . ASP C 1 328 ? -44.265 -57.709 3.528   1.00 46.76  ? 307 ASP C C   1 
ATOM   8818  O  O   . ASP C 1 328 ? -45.025 -58.603 3.908   1.00 39.37  ? 307 ASP C O   1 
ATOM   8819  C  CB  . ASP C 1 328 ? -41.949 -58.260 4.235   1.00 38.28  ? 307 ASP C CB  1 
ATOM   8820  C  CG  . ASP C 1 328 ? -40.671 -57.808 4.903   1.00 41.60  ? 307 ASP C CG  1 
ATOM   8821  O  OD1 . ASP C 1 328 ? -40.597 -56.666 5.406   1.00 39.96  ? 307 ASP C OD1 1 
ATOM   8822  O  OD2 . ASP C 1 328 ? -39.711 -58.615 4.921   1.00 66.57  ? 307 ASP C OD2 1 
ATOM   8823  N  N   . THR C 1 329 ? -44.407 -57.101 2.365   1.00 33.85  ? 308 THR C N   1 
ATOM   8824  C  CA  . THR C 1 329 ? -45.489 -57.470 1.473   1.00 38.65  ? 308 THR C CA  1 
ATOM   8825  C  C   . THR C 1 329 ? -45.046 -57.148 0.050   1.00 45.60  ? 308 THR C C   1 
ATOM   8826  O  O   . THR C 1 329 ? -43.906 -56.736 -0.191  1.00 44.43  ? 308 THR C O   1 
ATOM   8827  C  CB  . THR C 1 329 ? -46.796 -56.763 1.879   1.00 41.05  ? 308 THR C CB  1 
ATOM   8828  O  OG1 . THR C 1 329 ? -47.866 -57.198 1.034   1.00 49.71  ? 308 THR C OG1 1 
ATOM   8829  C  CG2 . THR C 1 329 ? -46.662 -55.254 1.767   1.00 42.05  ? 308 THR C CG2 1 
ATOM   8830  N  N   . GLU C 1 330 ? -45.940 -57.378 -0.899  1.00 46.00  ? 309 GLU C N   1 
ATOM   8831  C  CA  . GLU C 1 330 ? -45.607 -57.205 -2.303  1.00 56.24  ? 309 GLU C CA  1 
ATOM   8832  C  C   . GLU C 1 330 ? -46.743 -56.473 -2.992  1.00 51.34  ? 309 GLU C C   1 
ATOM   8833  O  O   . GLU C 1 330 ? -47.916 -56.724 -2.703  1.00 63.18  ? 309 GLU C O   1 
ATOM   8834  C  CB  . GLU C 1 330 ? -45.345 -58.553 -2.987  1.00 52.50  ? 309 GLU C CB  1 
ATOM   8835  C  CG  . GLU C 1 330 ? -44.071 -58.569 -3.819  1.00 70.66  ? 309 GLU C CG  1 
ATOM   8836  C  CD  . GLU C 1 330 ? -43.718 -59.954 -4.334  1.00 87.43  ? 309 GLU C CD  1 
ATOM   8837  O  OE1 . GLU C 1 330 ? -44.639 -60.686 -4.753  1.00 91.65  ? 309 GLU C OE1 1 
ATOM   8838  O  OE2 . GLU C 1 330 ? -42.518 -60.313 -4.314  1.00 92.06  ? 309 GLU C OE2 1 
ATOM   8839  N  N   . PHE C 1 331 ? -46.394 -55.547 -3.879  1.00 42.09  ? 310 PHE C N   1 
ATOM   8840  C  CA  . PHE C 1 331 ? -47.377 -54.837 -4.690  1.00 40.88  ? 310 PHE C CA  1 
ATOM   8841  C  C   . PHE C 1 331 ? -46.915 -54.879 -6.143  1.00 38.02  ? 310 PHE C C   1 
ATOM   8842  O  O   . PHE C 1 331 ? -45.890 -54.282 -6.489  1.00 40.21  ? 310 PHE C O   1 
ATOM   8843  C  CB  . PHE C 1 331 ? -47.555 -53.396 -4.202  1.00 35.89  ? 310 PHE C CB  1 
ATOM   8844  C  CG  . PHE C 1 331 ? -48.541 -52.587 -5.018  1.00 36.10  ? 310 PHE C CG  1 
ATOM   8845  C  CD1 . PHE C 1 331 ? -49.895 -52.846 -4.938  1.00 44.77  ? 310 PHE C CD1 1 
ATOM   8846  C  CD2 . PHE C 1 331 ? -48.101 -51.590 -5.872  1.00 37.38  ? 310 PHE C CD2 1 
ATOM   8847  C  CE1 . PHE C 1 331 ? -50.798 -52.112 -5.682  1.00 38.63  ? 310 PHE C CE1 1 
ATOM   8848  C  CE2 . PHE C 1 331 ? -49.004 -50.834 -6.635  1.00 41.34  ? 310 PHE C CE2 1 
ATOM   8849  C  CZ  . PHE C 1 331 ? -50.349 -51.093 -6.537  1.00 45.76  ? 310 PHE C CZ  1 
ATOM   8850  N  N   . GLU C 1 332 ? -47.672 -55.573 -6.985  1.00 46.27  ? 311 GLU C N   1 
ATOM   8851  C  CA  . GLU C 1 332 ? -47.387 -55.666 -8.418  1.00 48.03  ? 311 GLU C CA  1 
ATOM   8852  C  C   . GLU C 1 332 ? -45.920 -56.007 -8.680  1.00 50.57  ? 311 GLU C C   1 
ATOM   8853  O  O   . GLU C 1 332 ? -45.231 -55.360 -9.475  1.00 51.72  ? 311 GLU C O   1 
ATOM   8854  C  CB  . GLU C 1 332 ? -47.793 -54.370 -9.107  1.00 46.25  ? 311 GLU C CB  1 
ATOM   8855  C  CG  . GLU C 1 332 ? -49.124 -53.870 -8.573  1.00 44.40  ? 311 GLU C CG  1 
ATOM   8856  C  CD  . GLU C 1 332 ? -49.924 -53.092 -9.596  1.00 66.38  ? 311 GLU C CD  1 
ATOM   8857  O  OE1 . GLU C 1 332 ? -49.397 -52.083 -10.110 1.00 60.01  ? 311 GLU C OE1 1 
ATOM   8858  O  OE2 . GLU C 1 332 ? -51.076 -53.496 -9.882  1.00 64.93  ? 311 GLU C OE2 1 
ATOM   8859  N  N   . GLY C 1 333 ? -45.433 -57.023 -7.964  1.00 61.03  ? 312 GLY C N   1 
ATOM   8860  C  CA  . GLY C 1 333 ? -44.062 -57.478 -8.083  1.00 57.97  ? 312 GLY C CA  1 
ATOM   8861  C  C   . GLY C 1 333 ? -43.025 -56.648 -7.358  1.00 59.72  ? 312 GLY C C   1 
ATOM   8862  O  O   . GLY C 1 333 ? -41.872 -57.080 -7.264  1.00 63.79  ? 312 GLY C O   1 
ATOM   8863  N  N   . CYS C 1 334 ? -43.379 -55.478 -6.857  1.00 54.33  ? 313 CYS C N   1 
ATOM   8864  C  CA  . CYS C 1 334 ? -42.436 -54.656 -6.110  1.00 47.92  ? 313 CYS C CA  1 
ATOM   8865  C  C   . CYS C 1 334 ? -42.395 -55.121 -4.658  1.00 55.59  ? 313 CYS C C   1 
ATOM   8866  O  O   . CYS C 1 334 ? -43.453 -55.334 -4.050  1.00 40.10  ? 313 CYS C O   1 
ATOM   8867  C  CB  . CYS C 1 334 ? -42.842 -53.175 -6.194  1.00 65.48  ? 313 CYS C CB  1 
ATOM   8868  S  SG  . CYS C 1 334 ? -42.048 -51.976 -5.051  1.00 63.91  ? 313 CYS C SG  1 
ATOM   8869  N  N   . PRO C 1 335 ? -41.209 -55.318 -4.078  1.00 59.86  ? 314 PRO C N   1 
ATOM   8870  C  CA  . PRO C 1 335 ? -41.142 -55.644 -2.646  1.00 49.46  ? 314 PRO C CA  1 
ATOM   8871  C  C   . PRO C 1 335 ? -41.448 -54.412 -1.805  1.00 42.11  ? 314 PRO C C   1 
ATOM   8872  O  O   . PRO C 1 335 ? -40.959 -53.318 -2.089  1.00 49.48  ? 314 PRO C O   1 
ATOM   8873  C  CB  . PRO C 1 335 ? -39.696 -56.113 -2.454  1.00 42.75  ? 314 PRO C CB  1 
ATOM   8874  C  CG  . PRO C 1 335 ? -38.925 -55.409 -3.544  1.00 54.61  ? 314 PRO C CG  1 
ATOM   8875  C  CD  . PRO C 1 335 ? -39.874 -55.275 -4.711  1.00 50.13  ? 314 PRO C CD  1 
ATOM   8876  N  N   . ILE C 1 336 ? -42.288 -54.589 -0.787  1.00 38.91  ? 315 ILE C N   1 
ATOM   8877  C  CA  . ILE C 1 336 ? -42.531 -53.562 0.222   1.00 35.33  ? 315 ILE C CA  1 
ATOM   8878  C  C   . ILE C 1 336 ? -42.014 -54.101 1.551   1.00 37.98  ? 315 ILE C C   1 
ATOM   8879  O  O   . ILE C 1 336 ? -42.470 -55.155 2.012   1.00 40.79  ? 315 ILE C O   1 
ATOM   8880  C  CB  . ILE C 1 336 ? -44.023 -53.212 0.337   1.00 38.11  ? 315 ILE C CB  1 
ATOM   8881  C  CG1 . ILE C 1 336 ? -44.613 -52.793 -1.011  1.00 39.54  ? 315 ILE C CG1 1 
ATOM   8882  C  CG2 . ILE C 1 336 ? -44.220 -52.151 1.430   1.00 38.47  ? 315 ILE C CG2 1 
ATOM   8883  C  CD1 . ILE C 1 336 ? -44.114 -51.480 -1.475  1.00 43.12  ? 315 ILE C CD1 1 
ATOM   8884  N  N   A HIS C 1 337 ? -41.099 -53.363 2.176   0.50 35.72  ? 316 HIS C N   1 
ATOM   8885  N  N   B HIS C 1 337 ? -41.068 -53.410 2.179   0.50 35.75  ? 316 HIS C N   1 
ATOM   8886  C  CA  A HIS C 1 337 ? -40.472 -53.793 3.417   0.50 38.93  ? 316 HIS C CA  1 
ATOM   8887  C  CA  B HIS C 1 337 ? -40.504 -53.951 3.409   0.50 38.85  ? 316 HIS C CA  1 
ATOM   8888  C  C   A HIS C 1 337 ? -41.250 -53.256 4.610   0.50 37.55  ? 316 HIS C C   1 
ATOM   8889  C  C   B HIS C 1 337 ? -41.095 -53.263 4.629   0.50 37.70  ? 316 HIS C C   1 
ATOM   8890  O  O   A HIS C 1 337 ? -41.752 -52.130 4.577   0.50 34.31  ? 316 HIS C O   1 
ATOM   8891  O  O   B HIS C 1 337 ? -41.325 -52.051 4.626   0.50 33.90  ? 316 HIS C O   1 
ATOM   8892  C  CB  A HIS C 1 337 ? -39.017 -53.310 3.487   0.50 33.78  ? 316 HIS C CB  1 
ATOM   8893  C  CB  B HIS C 1 337 ? -38.971 -53.871 3.443   0.50 38.66  ? 316 HIS C CB  1 
ATOM   8894  C  CG  A HIS C 1 337 ? -38.296 -53.374 2.172   0.50 39.64  ? 316 HIS C CG  1 
ATOM   8895  C  CG  B HIS C 1 337 ? -38.406 -52.486 3.397   0.50 33.71  ? 316 HIS C CG  1 
ATOM   8896  N  ND1 A HIS C 1 337 ? -38.081 -54.554 1.494   0.50 45.16  ? 316 HIS C ND1 1 
ATOM   8897  N  ND1 B HIS C 1 337 ? -38.079 -51.774 4.532   0.50 38.12  ? 316 HIS C ND1 1 
ATOM   8898  C  CD2 A HIS C 1 337 ? -37.754 -52.398 1.405   0.50 44.36  ? 316 HIS C CD2 1 
ATOM   8899  C  CD2 B HIS C 1 337 ? -38.046 -51.708 2.349   0.50 37.31  ? 316 HIS C CD2 1 
ATOM   8900  C  CE1 A HIS C 1 337 ? -37.431 -54.305 0.371   0.50 41.11  ? 316 HIS C CE1 1 
ATOM   8901  C  CE1 B HIS C 1 337 ? -37.571 -50.606 4.183   0.50 31.94  ? 316 HIS C CE1 1 
ATOM   8902  N  NE2 A HIS C 1 337 ? -37.219 -53.005 0.294   0.50 46.47  ? 316 HIS C NE2 1 
ATOM   8903  N  NE2 B HIS C 1 337 ? -37.533 -50.543 2.865   0.50 37.62  ? 316 HIS C NE2 1 
ATOM   8904  N  N   . GLN C 1 338 ? -41.349 -54.068 5.662   1.00 32.51  ? 317 GLN C N   1 
ATOM   8905  C  CA  . GLN C 1 338 ? -41.887 -53.583 6.934   1.00 41.39  ? 317 GLN C CA  1 
ATOM   8906  C  C   . GLN C 1 338 ? -41.200 -52.291 7.355   1.00 35.00  ? 317 GLN C C   1 
ATOM   8907  O  O   . GLN C 1 338 ? -39.984 -52.148 7.222   1.00 35.22  ? 317 GLN C O   1 
ATOM   8908  C  CB  . GLN C 1 338 ? -41.701 -54.660 8.018   1.00 39.77  ? 317 GLN C CB  1 
ATOM   8909  C  CG  . GLN C 1 338 ? -42.205 -54.292 9.411   1.00 35.56  ? 317 GLN C CG  1 
ATOM   8910  C  CD  . GLN C 1 338 ? -41.244 -53.380 10.150  1.00 52.29  ? 317 GLN C CD  1 
ATOM   8911  O  OE1 . GLN C 1 338 ? -40.029 -53.552 10.058  1.00 68.59  ? 317 GLN C OE1 1 
ATOM   8912  N  NE2 . GLN C 1 338 ? -41.776 -52.390 10.857  1.00 55.12  ? 317 GLN C NE2 1 
ATOM   8913  N  N   . GLY C 1 339 ? -41.993 -51.331 7.842   1.00 34.70  ? 318 GLY C N   1 
ATOM   8914  C  CA  . GLY C 1 339 ? -41.476 -50.053 8.268   1.00 36.08  ? 318 GLY C CA  1 
ATOM   8915  C  C   . GLY C 1 339 ? -41.399 -48.973 7.196   1.00 33.01  ? 318 GLY C C   1 
ATOM   8916  O  O   . GLY C 1 339 ? -41.302 -47.792 7.537   1.00 35.21  ? 318 GLY C O   1 
ATOM   8917  N  N   . GLN C 1 340 ? -41.435 -49.325 5.914   1.00 35.28  ? 319 GLN C N   1 
ATOM   8918  C  CA  . GLN C 1 340 ? -41.339 -48.236 4.945   1.00 38.09  ? 319 GLN C CA  1 
ATOM   8919  C  C   . GLN C 1 340 ? -42.696 -47.536 4.780   1.00 32.28  ? 319 GLN C C   1 
ATOM   8920  O  O   . GLN C 1 340 ? -43.741 -48.030 5.226   1.00 27.91  ? 319 GLN C O   1 
ATOM   8921  C  CB  . GLN C 1 340 ? -40.860 -48.738 3.594   1.00 28.49  ? 319 GLN C CB  1 
ATOM   8922  C  CG  . GLN C 1 340 ? -41.865 -49.585 2.870   1.00 27.24  ? 319 GLN C CG  1 
ATOM   8923  C  CD  . GLN C 1 340 ? -41.557 -49.726 1.388   1.00 40.66  ? 319 GLN C CD  1 
ATOM   8924  O  OE1 . GLN C 1 340 ? -40.947 -50.707 0.950   1.00 36.55  ? 319 GLN C OE1 1 
ATOM   8925  N  NE2 . GLN C 1 340 ? -41.997 -48.756 0.608   1.00 37.53  ? 319 GLN C NE2 1 
ATOM   8926  N  N   . ARG C 1 341 ? -42.657 -46.355 4.161   1.00 27.27  ? 320 ARG C N   1 
ATOM   8927  C  CA  . ARG C 1 341 ? -43.893 -45.673 3.789   1.00 26.59  ? 320 ARG C CA  1 
ATOM   8928  C  C   . ARG C 1 341 ? -44.463 -46.186 2.467   1.00 28.99  ? 320 ARG C C   1 
ATOM   8929  O  O   . ARG C 1 341 ? -43.733 -46.515 1.523   1.00 28.54  ? 320 ARG C O   1 
ATOM   8930  C  CB  . ARG C 1 341 ? -43.660 -44.172 3.692   1.00 28.77  ? 320 ARG C CB  1 
ATOM   8931  C  CG  . ARG C 1 341 ? -43.560 -43.498 5.030   1.00 37.28  ? 320 ARG C CG  1 
ATOM   8932  C  CD  . ARG C 1 341 ? -43.557 -41.976 4.903   1.00 27.40  ? 320 ARG C CD  1 
ATOM   8933  N  NE  . ARG C 1 341 ? -43.580 -41.373 6.226   1.00 32.71  ? 320 ARG C NE  1 
ATOM   8934  C  CZ  . ARG C 1 341 ? -42.502 -41.278 6.991   1.00 48.38  ? 320 ARG C CZ  1 
ATOM   8935  N  NH1 . ARG C 1 341 ? -41.316 -41.682 6.560   1.00 46.25  ? 320 ARG C NH1 1 
ATOM   8936  N  NH2 . ARG C 1 341 ? -42.617 -40.780 8.222   1.00 37.08  ? 320 ARG C NH2 1 
ATOM   8937  N  N   . VAL C 1 342 ? -45.789 -46.238 2.403   1.00 26.53  ? 321 VAL C N   1 
ATOM   8938  C  CA  . VAL C 1 342 ? -46.529 -46.404 1.158   1.00 26.68  ? 321 VAL C CA  1 
ATOM   8939  C  C   . VAL C 1 342 ? -47.357 -45.145 1.031   1.00 26.46  ? 321 VAL C C   1 
ATOM   8940  O  O   . VAL C 1 342 ? -47.987 -44.733 2.011   1.00 25.69  ? 321 VAL C O   1 
ATOM   8941  C  CB  . VAL C 1 342 ? -47.427 -47.654 1.164   1.00 27.80  ? 321 VAL C CB  1 
ATOM   8942  C  CG1 . VAL C 1 342 ? -48.301 -47.681 -0.142  1.00 27.40  ? 321 VAL C CG1 1 
ATOM   8943  C  CG2 . VAL C 1 342 ? -46.587 -48.915 1.296   1.00 28.06  ? 321 VAL C CG2 1 
ATOM   8944  N  N   . ILE C 1 343 ? -47.281 -44.484 -0.120  1.00 24.60  ? 322 ILE C N   1 
ATOM   8945  C  CA  . ILE C 1 343 ? -47.934 -43.192 -0.310  1.00 25.34  ? 322 ILE C CA  1 
ATOM   8946  C  C   . ILE C 1 343 ? -48.938 -43.343 -1.437  1.00 27.28  ? 322 ILE C C   1 
ATOM   8947  O  O   . ILE C 1 343 ? -48.558 -43.707 -2.558  1.00 25.06  ? 322 ILE C O   1 
ATOM   8948  C  CB  . ILE C 1 343 ? -46.914 -42.090 -0.641  1.00 25.11  ? 322 ILE C CB  1 
ATOM   8949  C  CG1 . ILE C 1 343 ? -45.995 -41.907 0.563   1.00 28.55  ? 322 ILE C CG1 1 
ATOM   8950  C  CG2 . ILE C 1 343 ? -47.617 -40.772 -1.050  1.00 23.45  ? 322 ILE C CG2 1 
ATOM   8951  C  CD1 . ILE C 1 343 ? -44.899 -40.898 0.328   1.00 34.15  ? 322 ILE C CD1 1 
ATOM   8952  N  N   . LEU C 1 344 ? -50.217 -43.100 -1.138  1.00 24.46  ? 323 LEU C N   1 
ATOM   8953  C  CA  . LEU C 1 344 ? -51.249 -43.115 -2.178  1.00 24.16  ? 323 LEU C CA  1 
ATOM   8954  C  C   . LEU C 1 344 ? -51.269 -41.751 -2.864  1.00 23.24  ? 323 LEU C C   1 
ATOM   8955  O  O   . LEU C 1 344 ? -51.486 -40.733 -2.202  1.00 23.65  ? 323 LEU C O   1 
ATOM   8956  C  CB  . LEU C 1 344 ? -52.612 -43.444 -1.551  1.00 28.15  ? 323 LEU C CB  1 
ATOM   8957  C  CG  . LEU C 1 344 ? -53.832 -43.444 -2.494  1.00 20.50  ? 323 LEU C CG  1 
ATOM   8958  C  CD1 . LEU C 1 344 ? -53.632 -44.454 -3.585  1.00 22.16  ? 323 LEU C CD1 1 
ATOM   8959  C  CD2 . LEU C 1 344 ? -55.163 -43.771 -1.707  1.00 21.02  ? 323 LEU C CD2 1 
ATOM   8960  N  N   . ASP C 1 345 ? -51.024 -41.731 -4.181  1.00 23.57  ? 324 ASP C N   1 
ATOM   8961  C  CA  . ASP C 1 345 ? -51.026 -40.515 -5.000  1.00 21.68  ? 324 ASP C CA  1 
ATOM   8962  C  C   . ASP C 1 345 ? -52.479 -40.177 -5.374  1.00 20.95  ? 324 ASP C C   1 
ATOM   8963  O  O   . ASP C 1 345 ? -53.126 -40.919 -6.121  1.00 26.04  ? 324 ASP C O   1 
ATOM   8964  C  CB  . ASP C 1 345 ? -50.135 -40.767 -6.217  1.00 23.47  ? 324 ASP C CB  1 
ATOM   8965  C  CG  . ASP C 1 345 ? -50.319 -39.747 -7.341  1.00 31.52  ? 324 ASP C CG  1 
ATOM   8966  O  OD1 . ASP C 1 345 ? -50.814 -38.629 -7.091  1.00 24.60  ? 324 ASP C OD1 1 
ATOM   8967  O  OD2 . ASP C 1 345 ? -49.951 -40.098 -8.493  1.00 27.76  ? 324 ASP C OD2 1 
ATOM   8968  N  N   . PHE C 1 346 ? -53.025 -39.104 -4.779  1.00 21.34  ? 325 PHE C N   1 
ATOM   8969  C  CA  . PHE C 1 346 ? -54.454 -38.809 -4.972  1.00 24.75  ? 325 PHE C CA  1 
ATOM   8970  C  C   . PHE C 1 346 ? -54.682 -38.180 -6.341  1.00 24.11  ? 325 PHE C C   1 
ATOM   8971  O  O   . PHE C 1 346 ? -55.612 -38.557 -7.065  1.00 23.13  ? 325 PHE C O   1 
ATOM   8972  C  CB  . PHE C 1 346 ? -54.977 -37.859 -3.882  1.00 22.42  ? 325 PHE C CB  1 
ATOM   8973  C  CG  . PHE C 1 346 ? -55.398 -38.530 -2.570  1.00 24.80  ? 325 PHE C CG  1 
ATOM   8974  C  CD1 . PHE C 1 346 ? -54.608 -39.480 -1.968  1.00 23.25  ? 325 PHE C CD1 1 
ATOM   8975  C  CD2 . PHE C 1 346 ? -56.583 -38.146 -1.934  1.00 23.26  ? 325 PHE C CD2 1 
ATOM   8976  C  CE1 . PHE C 1 346 ? -54.998 -40.093 -0.771  1.00 27.51  ? 325 PHE C CE1 1 
ATOM   8977  C  CE2 . PHE C 1 346 ? -56.997 -38.771 -0.721  1.00 27.16  ? 325 PHE C CE2 1 
ATOM   8978  C  CZ  . PHE C 1 346 ? -56.177 -39.732 -0.142  1.00 25.41  ? 325 PHE C CZ  1 
ATOM   8979  N  N   . VAL C 1 347 ? -53.843 -37.201 -6.699  1.00 20.54  ? 326 VAL C N   1 
ATOM   8980  C  CA  . VAL C 1 347 ? -53.962 -36.538 -8.002  1.00 24.77  ? 326 VAL C CA  1 
ATOM   8981  C  C   . VAL C 1 347 ? -53.886 -37.558 -9.126  1.00 24.65  ? 326 VAL C C   1 
ATOM   8982  O  O   . VAL C 1 347 ? -54.691 -37.533 -10.070 1.00 24.07  ? 326 VAL C O   1 
ATOM   8983  C  CB  . VAL C 1 347 ? -52.873 -35.467 -8.155  1.00 29.12  ? 326 VAL C CB  1 
ATOM   8984  C  CG1 . VAL C 1 347 ? -52.857 -34.915 -9.606  1.00 27.34  ? 326 VAL C CG1 1 
ATOM   8985  C  CG2 . VAL C 1 347 ? -53.136 -34.339 -7.146  1.00 26.19  ? 326 VAL C CG2 1 
ATOM   8986  N  N   . GLY C 1 348 ? -52.916 -38.475 -9.042  1.00 22.20  ? 327 GLY C N   1 
ATOM   8987  C  CA  . GLY C 1 348 ? -52.761 -39.454 -10.106 1.00 23.26  ? 327 GLY C CA  1 
ATOM   8988  C  C   . GLY C 1 348 ? -53.830 -40.525 -10.120 1.00 27.32  ? 327 GLY C C   1 
ATOM   8989  O  O   . GLY C 1 348 ? -53.971 -41.224 -11.127 1.00 27.83  ? 327 GLY C O   1 
ATOM   8990  N  N   . THR C 1 349 ? -54.555 -40.713 -9.015  1.00 21.99  ? 328 THR C N   1 
ATOM   8991  C  CA  . THR C 1 349 ? -55.718 -41.603 -9.078  1.00 22.60  ? 328 THR C CA  1 
ATOM   8992  C  C   . THR C 1 349 ? -56.923 -40.888 -9.685  1.00 25.27  ? 328 THR C C   1 
ATOM   8993  O  O   . THR C 1 349 ? -57.671 -41.469 -10.490 1.00 24.90  ? 328 THR C O   1 
ATOM   8994  C  CB  . THR C 1 349 ? -56.068 -42.116 -7.683  1.00 20.88  ? 328 THR C CB  1 
ATOM   8995  O  OG1 . THR C 1 349 ? -54.945 -42.806 -7.124  1.00 25.63  ? 328 THR C OG1 1 
ATOM   8996  C  CG2 . THR C 1 349 ? -57.287 -43.100 -7.728  1.00 19.96  ? 328 THR C CG2 1 
ATOM   8997  N  N   . LEU C 1 350 ? -57.141 -39.645 -9.256  1.00 18.36  ? 329 LEU C N   1 
ATOM   8998  C  CA  . LEU C 1 350 ? -58.245 -38.820 -9.742  1.00 20.94  ? 329 LEU C CA  1 
ATOM   8999  C  C   . LEU C 1 350 ? -58.089 -38.455 -11.212 1.00 25.97  ? 329 LEU C C   1 
ATOM   9000  O  O   . LEU C 1 350 ? -59.088 -38.130 -11.885 1.00 22.16  ? 329 LEU C O   1 
ATOM   9001  C  CB  . LEU C 1 350 ? -58.323 -37.541 -8.896  1.00 19.46  ? 329 LEU C CB  1 
ATOM   9002  C  CG  . LEU C 1 350 ? -58.758 -37.765 -7.447  1.00 23.91  ? 329 LEU C CG  1 
ATOM   9003  C  CD1 . LEU C 1 350 ? -58.627 -36.453 -6.653  1.00 20.43  ? 329 LEU C CD1 1 
ATOM   9004  C  CD2 . LEU C 1 350 ? -60.239 -38.256 -7.431  1.00 20.28  ? 329 LEU C CD2 1 
ATOM   9005  N  N   . HIS C 1 351 ? -56.861 -38.479 -11.722 1.00 20.60  ? 330 HIS C N   1 
ATOM   9006  C  CA  . HIS C 1 351 ? -56.597 -38.085 -13.108 1.00 21.90  ? 330 HIS C CA  1 
ATOM   9007  C  C   . HIS C 1 351 ? -56.053 -39.225 -13.960 1.00 28.01  ? 330 HIS C C   1 
ATOM   9008  O  O   . HIS C 1 351 ? -55.537 -38.979 -15.057 1.00 24.06  ? 330 HIS C O   1 
ATOM   9009  C  CB  . HIS C 1 351 ? -55.625 -36.912 -13.132 1.00 21.46  ? 330 HIS C CB  1 
ATOM   9010  C  CG  . HIS C 1 351 ? -56.273 -35.613 -12.772 1.00 27.39  ? 330 HIS C CG  1 
ATOM   9011  N  ND1 . HIS C 1 351 ? -56.667 -34.692 -13.720 1.00 25.02  ? 330 HIS C ND1 1 
ATOM   9012  C  CD2 . HIS C 1 351 ? -56.632 -35.100 -11.569 1.00 27.26  ? 330 HIS C CD2 1 
ATOM   9013  C  CE1 . HIS C 1 351 ? -57.239 -33.661 -13.113 1.00 28.85  ? 330 HIS C CE1 1 
ATOM   9014  N  NE2 . HIS C 1 351 ? -57.231 -33.886 -11.808 1.00 26.32  ? 330 HIS C NE2 1 
ATOM   9015  N  N   . SER C 1 352 ? -56.151 -40.458 -13.483 1.00 24.29  ? 331 SER C N   1 
ATOM   9016  C  CA  . SER C 1 352 ? -55.589 -41.583 -14.220 1.00 27.03  ? 331 SER C CA  1 
ATOM   9017  C  C   . SER C 1 352 ? -56.414 -41.872 -15.471 1.00 25.61  ? 331 SER C C   1 
ATOM   9018  O  O   . SER C 1 352 ? -57.650 -41.929 -15.422 1.00 26.34  ? 331 SER C O   1 
ATOM   9019  C  CB  . SER C 1 352 ? -55.539 -42.808 -13.311 1.00 29.01  ? 331 SER C CB  1 
ATOM   9020  O  OG  . SER C 1 352 ? -55.339 -43.990 -14.061 1.00 28.67  ? 331 SER C OG  1 
ATOM   9021  N  N   . ALA C 1 353 ? -55.730 -42.035 -16.606 1.00 24.22  ? 332 ALA C N   1 
ATOM   9022  C  CA  . ALA C 1 353 ? -56.431 -42.403 -17.832 1.00 28.26  ? 332 ALA C CA  1 
ATOM   9023  C  C   . ALA C 1 353 ? -56.882 -43.852 -17.806 1.00 31.68  ? 332 ALA C C   1 
ATOM   9024  O  O   . ALA C 1 353 ? -57.780 -44.222 -18.561 1.00 29.72  ? 332 ALA C O   1 
ATOM   9025  C  CB  . ALA C 1 353 ? -55.530 -42.155 -19.052 1.00 30.10  ? 332 ALA C CB  1 
ATOM   9026  N  N   . GLU C 1 354 ? -56.282 -44.685 -16.950 1.00 25.57  ? 333 GLU C N   1 
ATOM   9027  C  CA  . GLU C 1 354 ? -56.781 -46.045 -16.811 1.00 29.04  ? 333 GLU C CA  1 
ATOM   9028  C  C   . GLU C 1 354 ? -58.106 -46.077 -16.073 1.00 33.62  ? 333 GLU C C   1 
ATOM   9029  O  O   . GLU C 1 354 ? -58.893 -47.006 -16.264 1.00 36.44  ? 333 GLU C O   1 
ATOM   9030  C  CB  . GLU C 1 354 ? -55.769 -46.912 -16.063 1.00 33.84  ? 333 GLU C CB  1 
ATOM   9031  C  CG  . GLU C 1 354 ? -54.561 -47.283 -16.883 1.00 41.61  ? 333 GLU C CG  1 
ATOM   9032  C  CD  . GLU C 1 354 ? -54.931 -48.282 -17.952 1.00 64.42  ? 333 GLU C CD  1 
ATOM   9033  O  OE1 . GLU C 1 354 ? -55.809 -49.128 -17.670 1.00 62.10  ? 333 GLU C OE1 1 
ATOM   9034  O  OE2 . GLU C 1 354 ? -54.375 -48.205 -19.070 1.00 76.22  ? 333 GLU C OE2 1 
ATOM   9035  N  N   . GLU C 1 355 ? -58.368 -45.100 -15.214 1.00 23.56  ? 334 GLU C N   1 
ATOM   9036  C  CA  . GLU C 1 355 ? -59.548 -45.191 -14.348 1.00 28.09  ? 334 GLU C CA  1 
ATOM   9037  C  C   . GLU C 1 355 ? -60.686 -44.287 -14.784 1.00 26.30  ? 334 GLU C C   1 
ATOM   9038  O  O   . GLU C 1 355 ? -61.802 -44.470 -14.300 1.00 25.24  ? 334 GLU C O   1 
ATOM   9039  C  CB  . GLU C 1 355 ? -59.223 -44.831 -12.881 1.00 30.94  ? 334 GLU C CB  1 
ATOM   9040  C  CG  . GLU C 1 355 ? -57.971 -45.507 -12.268 1.00 35.99  ? 334 GLU C CG  1 
ATOM   9041  C  CD  . GLU C 1 355 ? -58.277 -46.825 -11.611 1.00 35.02  ? 334 GLU C CD  1 
ATOM   9042  O  OE1 . GLU C 1 355 ? -59.466 -47.117 -11.393 1.00 39.97  ? 334 GLU C OE1 1 
ATOM   9043  O  OE2 . GLU C 1 355 ? -57.313 -47.577 -11.320 1.00 38.78  ? 334 GLU C OE2 1 
ATOM   9044  N  N   . TRP C 1 356 ? -60.414 -43.276 -15.616 1.00 25.99  ? 335 TRP C N   1 
ATOM   9045  C  CA  . TRP C 1 356 ? -61.403 -42.295 -16.048 1.00 27.58  ? 335 TRP C CA  1 
ATOM   9046  C  C   . TRP C 1 356 ? -61.312 -42.095 -17.558 1.00 30.94  ? 335 TRP C C   1 
ATOM   9047  O  O   . TRP C 1 356 ? -60.225 -42.175 -18.127 1.00 29.67  ? 335 TRP C O   1 
ATOM   9048  C  CB  . TRP C 1 356 ? -61.166 -40.932 -15.394 1.00 23.46  ? 335 TRP C CB  1 
ATOM   9049  C  CG  . TRP C 1 356 ? -61.053 -40.961 -13.920 1.00 22.92  ? 335 TRP C CG  1 
ATOM   9050  C  CD1 . TRP C 1 356 ? -59.920 -41.180 -13.186 1.00 24.51  ? 335 TRP C CD1 1 
ATOM   9051  C  CD2 . TRP C 1 356 ? -62.117 -40.780 -12.977 1.00 22.21  ? 335 TRP C CD2 1 
ATOM   9052  N  NE1 . TRP C 1 356 ? -60.226 -41.145 -11.829 1.00 23.89  ? 335 TRP C NE1 1 
ATOM   9053  C  CE2 . TRP C 1 356 ? -61.560 -40.880 -11.685 1.00 23.76  ? 335 TRP C CE2 1 
ATOM   9054  C  CE3 . TRP C 1 356 ? -63.495 -40.516 -13.105 1.00 26.31  ? 335 TRP C CE3 1 
ATOM   9055  C  CZ2 . TRP C 1 356 ? -62.326 -40.742 -10.531 1.00 18.98  ? 335 TRP C CZ2 1 
ATOM   9056  C  CZ3 . TRP C 1 356 ? -64.248 -40.388 -11.974 1.00 24.79  ? 335 TRP C CZ3 1 
ATOM   9057  C  CH2 . TRP C 1 356 ? -63.660 -40.484 -10.684 1.00 19.64  ? 335 TRP C CH2 1 
ATOM   9058  N  N   . ASP C 1 357 ? -62.448 -41.788 -18.191 1.00 26.91  ? 336 ASP C N   1 
ATOM   9059  C  CA  . ASP C 1 357 ? -62.455 -41.329 -19.585 1.00 32.83  ? 336 ASP C CA  1 
ATOM   9060  C  C   . ASP C 1 357 ? -62.101 -39.849 -19.655 1.00 25.85  ? 336 ASP C C   1 
ATOM   9061  O  O   . ASP C 1 357 ? -62.687 -39.039 -18.934 1.00 29.34  ? 336 ASP C O   1 
ATOM   9062  C  CB  . ASP C 1 357 ? -63.827 -41.559 -20.220 1.00 32.05  ? 336 ASP C CB  1 
ATOM   9063  C  CG  . ASP C 1 357 ? -64.098 -43.031 -20.492 1.00 59.21  ? 336 ASP C CG  1 
ATOM   9064  O  OD1 . ASP C 1 357 ? -63.123 -43.765 -20.775 1.00 60.44  ? 336 ASP C OD1 1 
ATOM   9065  O  OD2 . ASP C 1 357 ? -65.273 -43.455 -20.418 1.00 64.61  ? 336 ASP C OD2 1 
ATOM   9066  N  N   . ASN C 1 358 ? -61.116 -39.503 -20.485 1.00 29.59  ? 337 ASN C N   1 
ATOM   9067  C  CA  . ASN C 1 358 ? -60.701 -38.119 -20.686 1.00 32.43  ? 337 ASN C CA  1 
ATOM   9068  C  C   . ASN C 1 358 ? -60.488 -37.399 -19.351 1.00 26.70  ? 337 ASN C C   1 
ATOM   9069  O  O   . ASN C 1 358 ? -61.150 -36.393 -19.074 1.00 24.77  ? 337 ASN C O   1 
ATOM   9070  C  CB  . ASN C 1 358 ? -61.722 -37.372 -21.535 1.00 30.62  ? 337 ASN C CB  1 
ATOM   9071  C  CG  . ASN C 1 358 ? -61.876 -37.981 -22.935 1.00 28.65  ? 337 ASN C CG  1 
ATOM   9072  O  OD1 . ASN C 1 358 ? -60.911 -38.084 -23.683 1.00 36.75  ? 337 ASN C OD1 1 
ATOM   9073  N  ND2 . ASN C 1 358 ? -63.093 -38.345 -23.288 1.00 30.01  ? 337 ASN C ND2 1 
ATOM   9074  N  N   . PRO C 1 359 ? -59.594 -37.909 -18.497 1.00 28.51  ? 338 PRO C N   1 
ATOM   9075  C  CA  . PRO C 1 359 ? -59.438 -37.323 -17.150 1.00 27.89  ? 338 PRO C CA  1 
ATOM   9076  C  C   . PRO C 1 359 ? -59.040 -35.868 -17.164 1.00 25.83  ? 338 PRO C C   1 
ATOM   9077  O  O   . PRO C 1 359 ? -59.290 -35.188 -16.166 1.00 22.88  ? 338 PRO C O   1 
ATOM   9078  C  CB  . PRO C 1 359 ? -58.338 -38.185 -16.502 1.00 25.77  ? 338 PRO C CB  1 
ATOM   9079  C  CG  . PRO C 1 359 ? -57.624 -38.819 -17.665 1.00 27.21  ? 338 PRO C CG  1 
ATOM   9080  C  CD  . PRO C 1 359 ? -58.666 -39.033 -18.725 1.00 28.58  ? 338 PRO C CD  1 
ATOM   9081  N  N   . ALA C 1 360 ? -58.410 -35.362 -18.235 1.00 24.22  ? 339 ALA C N   1 
ATOM   9082  C  CA  . ALA C 1 360 ? -58.022 -33.946 -18.244 1.00 25.57  ? 339 ALA C CA  1 
ATOM   9083  C  C   . ALA C 1 360 ? -59.198 -33.028 -18.527 1.00 21.05  ? 339 ALA C C   1 
ATOM   9084  O  O   . ALA C 1 360 ? -59.080 -31.787 -18.385 1.00 23.63  ? 339 ALA C O   1 
ATOM   9085  C  CB  . ALA C 1 360 ? -56.927 -33.680 -19.287 1.00 25.31  ? 339 ALA C CB  1 
ATOM   9086  N  N   . SER C 1 361 ? -60.326 -33.592 -18.911 1.00 20.99  ? 340 SER C N   1 
ATOM   9087  C  CA  . SER C 1 361 ? -61.515 -32.797 -19.228 1.00 19.65  ? 340 SER C CA  1 
ATOM   9088  C  C   . SER C 1 361 ? -62.336 -32.548 -17.959 1.00 22.16  ? 340 SER C C   1 
ATOM   9089  O  O   . SER C 1 361 ? -62.630 -33.484 -17.221 1.00 25.22  ? 340 SER C O   1 
ATOM   9090  C  CB  . SER C 1 361 ? -62.341 -33.543 -20.283 1.00 22.65  ? 340 SER C CB  1 
ATOM   9091  O  OG  . SER C 1 361 ? -63.564 -32.868 -20.546 1.00 27.94  ? 340 SER C OG  1 
ATOM   9092  N  N   . PHE C 1 362 ? -62.717 -31.289 -17.711 1.00 21.79  ? 341 PHE C N   1 
ATOM   9093  C  CA  . PHE C 1 362 ? -63.640 -30.972 -16.626 1.00 22.23  ? 341 PHE C CA  1 
ATOM   9094  C  C   . PHE C 1 362 ? -65.031 -31.233 -17.175 1.00 22.59  ? 341 PHE C C   1 
ATOM   9095  O  O   . PHE C 1 362 ? -65.474 -30.535 -18.089 1.00 22.86  ? 341 PHE C O   1 
ATOM   9096  C  CB  . PHE C 1 362 ? -63.504 -29.522 -16.158 1.00 22.87  ? 341 PHE C CB  1 
ATOM   9097  C  CG  . PHE C 1 362 ? -64.514 -29.129 -15.081 1.00 25.01  ? 341 PHE C CG  1 
ATOM   9098  C  CD1 . PHE C 1 362 ? -64.236 -29.349 -13.737 1.00 21.69  ? 341 PHE C CD1 1 
ATOM   9099  C  CD2 . PHE C 1 362 ? -65.743 -28.577 -15.412 1.00 23.66  ? 341 PHE C CD2 1 
ATOM   9100  C  CE1 . PHE C 1 362 ? -65.163 -29.008 -12.741 1.00 21.76  ? 341 PHE C CE1 1 
ATOM   9101  C  CE2 . PHE C 1 362 ? -66.674 -28.238 -14.426 1.00 22.05  ? 341 PHE C CE2 1 
ATOM   9102  C  CZ  . PHE C 1 362 ? -66.378 -28.452 -13.082 1.00 20.96  ? 341 PHE C CZ  1 
ATOM   9103  N  N   . ASP C 1 363 ? -65.717 -32.240 -16.656 1.00 21.20  ? 342 ASP C N   1 
ATOM   9104  C  CA  . ASP C 1 363 ? -66.968 -32.678 -17.276 1.00 25.59  ? 342 ASP C CA  1 
ATOM   9105  C  C   . ASP C 1 363 ? -67.931 -33.202 -16.217 1.00 23.02  ? 342 ASP C C   1 
ATOM   9106  O  O   . ASP C 1 363 ? -67.901 -34.386 -15.853 1.00 26.13  ? 342 ASP C O   1 
ATOM   9107  C  CB  . ASP C 1 363 ? -66.712 -33.731 -18.347 1.00 23.81  ? 342 ASP C CB  1 
ATOM   9108  C  CG  . ASP C 1 363 ? -67.980 -34.064 -19.145 1.00 37.84  ? 342 ASP C CG  1 
ATOM   9109  O  OD1 . ASP C 1 363 ? -69.054 -33.487 -18.846 1.00 30.94  ? 342 ASP C OD1 1 
ATOM   9110  O  OD2 . ASP C 1 363 ? -67.885 -34.886 -20.065 1.00 35.88  ? 342 ASP C OD2 1 
ATOM   9111  N  N   . PRO C 1 364 ? -68.835 -32.356 -15.737 1.00 20.51  ? 343 PRO C N   1 
ATOM   9112  C  CA  . PRO C 1 364 ? -69.812 -32.805 -14.742 1.00 22.70  ? 343 PRO C CA  1 
ATOM   9113  C  C   . PRO C 1 364 ? -70.747 -33.912 -15.222 1.00 21.59  ? 343 PRO C C   1 
ATOM   9114  O  O   . PRO C 1 364 ? -71.371 -34.556 -14.366 1.00 24.60  ? 343 PRO C O   1 
ATOM   9115  C  CB  . PRO C 1 364 ? -70.582 -31.524 -14.399 1.00 28.39  ? 343 PRO C CB  1 
ATOM   9116  C  CG  . PRO C 1 364 ? -69.506 -30.418 -14.557 1.00 21.53  ? 343 PRO C CG  1 
ATOM   9117  C  CD  . PRO C 1 364 ? -68.753 -30.894 -15.824 1.00 19.75  ? 343 PRO C CD  1 
ATOM   9118  N  N   . GLU C 1 365 ? -70.852 -34.175 -16.526 1.00 25.52  ? 344 GLU C N   1 
ATOM   9119  C  CA  . GLU C 1 365 ? -71.683 -35.306 -16.955 1.00 23.77  ? 344 GLU C CA  1 
ATOM   9120  C  C   . GLU C 1 365 ? -71.246 -36.605 -16.300 1.00 28.18  ? 344 GLU C C   1 
ATOM   9121  O  O   . GLU C 1 365 ? -72.069 -37.498 -16.103 1.00 25.21  ? 344 GLU C O   1 
ATOM   9122  C  CB  . GLU C 1 365 ? -71.629 -35.484 -18.475 1.00 29.59  ? 344 GLU C CB  1 
ATOM   9123  C  CG  . GLU C 1 365 ? -72.174 -34.327 -19.253 1.00 31.86  ? 344 GLU C CG  1 
ATOM   9124  C  CD  . GLU C 1 365 ? -73.693 -34.173 -19.149 1.00 45.03  ? 344 GLU C CD  1 
ATOM   9125  O  OE1 . GLU C 1 365 ? -74.369 -34.970 -18.434 1.00 35.16  ? 344 GLU C OE1 1 
ATOM   9126  O  OE2 . GLU C 1 365 ? -74.207 -33.230 -19.796 1.00 37.75  ? 344 GLU C OE2 1 
ATOM   9127  N  N   . ARG C 1 366 ? -69.952 -36.733 -15.967 1.00 26.15  ? 345 ARG C N   1 
ATOM   9128  C  CA  . ARG C 1 366 ? -69.444 -37.907 -15.255 1.00 25.65  ? 345 ARG C CA  1 
ATOM   9129  C  C   . ARG C 1 366 ? -70.282 -38.285 -14.050 1.00 25.95  ? 345 ARG C C   1 
ATOM   9130  O  O   . ARG C 1 366 ? -70.335 -39.468 -13.685 1.00 26.30  ? 345 ARG C O   1 
ATOM   9131  C  CB  . ARG C 1 366 ? -68.031 -37.678 -14.690 1.00 28.21  ? 345 ARG C CB  1 
ATOM   9132  C  CG  . ARG C 1 366 ? -66.980 -37.493 -15.620 1.00 38.10  ? 345 ARG C CG  1 
ATOM   9133  C  CD  . ARG C 1 366 ? -65.703 -37.228 -14.804 1.00 24.71  ? 345 ARG C CD  1 
ATOM   9134  N  NE  . ARG C 1 366 ? -64.802 -36.531 -15.684 1.00 22.95  ? 345 ARG C NE  1 
ATOM   9135  C  CZ  . ARG C 1 366 ? -64.143 -37.133 -16.653 1.00 24.77  ? 345 ARG C CZ  1 
ATOM   9136  N  NH1 . ARG C 1 366 ? -64.200 -38.456 -16.805 1.00 26.67  ? 345 ARG C NH1 1 
ATOM   9137  N  NH2 . ARG C 1 366 ? -63.423 -36.402 -17.496 1.00 30.13  ? 345 ARG C NH2 1 
ATOM   9138  N  N   . PHE C 1 367 ? -70.861 -37.301 -13.360 1.00 23.95  ? 346 PHE C N   1 
ATOM   9139  C  CA  . PHE C 1 367 ? -71.563 -37.564 -12.118 1.00 21.88  ? 346 PHE C CA  1 
ATOM   9140  C  C   . PHE C 1 367 ? -73.052 -37.331 -12.217 1.00 23.47  ? 346 PHE C C   1 
ATOM   9141  O  O   . PHE C 1 367 ? -73.740 -37.442 -11.196 1.00 26.17  ? 346 PHE C O   1 
ATOM   9142  C  CB  . PHE C 1 367 ? -70.978 -36.701 -10.977 1.00 21.90  ? 346 PHE C CB  1 
ATOM   9143  C  CG  . PHE C 1 367 ? -69.564 -37.044 -10.655 1.00 27.51  ? 346 PHE C CG  1 
ATOM   9144  C  CD1 . PHE C 1 367 ? -69.260 -38.194 -9.935  1.00 30.09  ? 346 PHE C CD1 1 
ATOM   9145  C  CD2 . PHE C 1 367 ? -68.525 -36.242 -11.128 1.00 22.21  ? 346 PHE C CD2 1 
ATOM   9146  C  CE1 . PHE C 1 367 ? -67.920 -38.513 -9.644  1.00 26.90  ? 346 PHE C CE1 1 
ATOM   9147  C  CE2 . PHE C 1 367 ? -67.203 -36.547 -10.840 1.00 24.97  ? 346 PHE C CE2 1 
ATOM   9148  C  CZ  . PHE C 1 367 ? -66.893 -37.681 -10.111 1.00 22.13  ? 346 PHE C CZ  1 
ATOM   9149  N  N   . MET C 1 368 ? -73.577 -37.017 -13.417 1.00 24.46  ? 347 MET C N   1 
ATOM   9150  C  CA  . MET C 1 368 ? -74.997 -36.685 -13.518 1.00 22.40  ? 347 MET C CA  1 
ATOM   9151  C  C   . MET C 1 368 ? -75.906 -37.870 -13.242 1.00 27.45  ? 347 MET C C   1 
ATOM   9152  O  O   . MET C 1 368 ? -77.051 -37.657 -12.816 1.00 26.83  ? 347 MET C O   1 
ATOM   9153  C  CB  . MET C 1 368 ? -75.308 -36.101 -14.890 1.00 25.40  ? 347 MET C CB  1 
ATOM   9154  C  CG  . MET C 1 368 ? -74.950 -34.640 -14.953 1.00 21.79  ? 347 MET C CG  1 
ATOM   9155  S  SD  . MET C 1 368 ? -76.015 -33.566 -13.975 1.00 29.63  ? 347 MET C SD  1 
ATOM   9156  C  CE  . MET C 1 368 ? -77.616 -33.805 -14.760 1.00 34.24  ? 347 MET C CE  1 
ATOM   9157  N  N   . ALA C 1 369 ? -75.415 -39.105 -13.411 1.00 22.57  ? 348 ALA C N   1 
ATOM   9158  C  CA  . ALA C 1 369 ? -76.254 -40.265 -13.123 1.00 24.27  ? 348 ALA C CA  1 
ATOM   9159  C  C   . ALA C 1 369 ? -76.310 -40.581 -11.641 1.00 30.37  ? 348 ALA C C   1 
ATOM   9160  O  O   . ALA C 1 369 ? -77.060 -41.479 -11.254 1.00 27.84  ? 348 ALA C O   1 
ATOM   9161  C  CB  . ALA C 1 369 ? -75.752 -41.515 -13.871 1.00 23.21  ? 348 ALA C CB  1 
ATOM   9162  N  N   . TYR C 1 370 ? -75.522 -39.886 -10.808 1.00 21.51  ? 349 TYR C N   1 
ATOM   9163  C  CA  . TYR C 1 370 ? -75.451 -40.172 -9.381  1.00 23.67  ? 349 TYR C CA  1 
ATOM   9164  C  C   . TYR C 1 370 ? -76.325 -39.203 -8.601  1.00 31.87  ? 349 TYR C C   1 
ATOM   9165  O  O   . TYR C 1 370 ? -76.429 -38.025 -8.949  1.00 30.91  ? 349 TYR C O   1 
ATOM   9166  C  CB  . TYR C 1 370 ? -73.985 -40.094 -8.913  1.00 23.15  ? 349 TYR C CB  1 
ATOM   9167  C  CG  . TYR C 1 370 ? -73.137 -41.212 -9.467  1.00 21.27  ? 349 TYR C CG  1 
ATOM   9168  C  CD1 . TYR C 1 370 ? -72.623 -41.174 -10.765 1.00 21.86  ? 349 TYR C CD1 1 
ATOM   9169  C  CD2 . TYR C 1 370 ? -72.860 -42.331 -8.687  1.00 22.58  ? 349 TYR C CD2 1 
ATOM   9170  C  CE1 . TYR C 1 370 ? -71.856 -42.221 -11.269 1.00 20.13  ? 349 TYR C CE1 1 
ATOM   9171  C  CE2 . TYR C 1 370 ? -72.096 -43.361 -9.164  1.00 19.43  ? 349 TYR C CE2 1 
ATOM   9172  C  CZ  . TYR C 1 370 ? -71.605 -43.318 -10.450 1.00 24.34  ? 349 TYR C CZ  1 
ATOM   9173  O  OH  . TYR C 1 370 ? -70.877 -44.395 -10.877 1.00 25.01  ? 349 TYR C OH  1 
ATOM   9174  N  N   . GLU C 1 371 ? -76.980 -39.707 -7.554  1.00 24.22  ? 350 GLU C N   1 
ATOM   9175  C  CA  . GLU C 1 371 ? -77.955 -38.913 -6.823  1.00 30.00  ? 350 GLU C CA  1 
ATOM   9176  C  C   . GLU C 1 371 ? -77.459 -38.411 -5.473  1.00 26.27  ? 350 GLU C C   1 
ATOM   9177  O  O   . GLU C 1 371 ? -77.930 -37.370 -5.007  1.00 30.25  ? 350 GLU C O   1 
ATOM   9178  C  CB  . GLU C 1 371 ? -79.238 -39.735 -6.618  1.00 27.45  ? 350 GLU C CB  1 
ATOM   9179  C  CG  . GLU C 1 371 ? -79.965 -40.032 -7.935  1.00 53.68  ? 350 GLU C CG  1 
ATOM   9180  C  CD  . GLU C 1 371 ? -81.274 -40.784 -7.728  1.00 67.79  ? 350 GLU C CD  1 
ATOM   9181  O  OE1 . GLU C 1 371 ? -81.482 -41.283 -6.599  1.00 61.17  ? 350 GLU C OE1 1 
ATOM   9182  O  OE2 . GLU C 1 371 ? -82.085 -40.869 -8.687  1.00 65.04  ? 350 GLU C OE2 1 
ATOM   9183  N  N   . THR C 1 372 ? -76.532 -39.117 -4.830  1.00 28.46  ? 351 THR C N   1 
ATOM   9184  C  CA  . THR C 1 372 ? -76.126 -38.820 -3.461  1.00 28.99  ? 351 THR C CA  1 
ATOM   9185  C  C   . THR C 1 372 ? -74.636 -39.068 -3.305  1.00 29.46  ? 351 THR C C   1 
ATOM   9186  O  O   . THR C 1 372 ? -74.022 -39.800 -4.088  1.00 23.02  ? 351 THR C O   1 
ATOM   9187  C  CB  . THR C 1 372 ? -76.840 -39.701 -2.428  1.00 27.54  ? 351 THR C CB  1 
ATOM   9188  O  OG1 . THR C 1 372 ? -76.499 -41.062 -2.687  1.00 29.16  ? 351 THR C OG1 1 
ATOM   9189  C  CG2 . THR C 1 372 ? -78.361 -39.550 -2.508  1.00 34.71  ? 351 THR C CG2 1 
ATOM   9190  N  N   . GLN C 1 373 ? -74.067 -38.527 -2.220  1.00 27.08  ? 352 GLN C N   1 
ATOM   9191  C  CA  . GLN C 1 373 ? -72.664 -38.830 -1.943  1.00 29.27  ? 352 GLN C CA  1 
ATOM   9192  C  C   . GLN C 1 373 ? -72.491 -40.305 -1.584  1.00 23.85  ? 352 GLN C C   1 
ATOM   9193  O  O   . GLN C 1 373 ? -71.481 -40.927 -1.936  1.00 25.80  ? 352 GLN C O   1 
ATOM   9194  C  CB  . GLN C 1 373 ? -72.143 -37.902 -0.840  1.00 29.32  ? 352 GLN C CB  1 
ATOM   9195  C  CG  . GLN C 1 373 ? -70.719 -38.236 -0.302  1.00 27.54  ? 352 GLN C CG  1 
ATOM   9196  C  CD  . GLN C 1 373 ? -69.653 -38.450 -1.352  1.00 27.35  ? 352 GLN C CD  1 
ATOM   9197  O  OE1 . GLN C 1 373 ? -69.687 -37.857 -2.426  1.00 34.57  ? 352 GLN C OE1 1 
ATOM   9198  N  NE2 . GLN C 1 373 ? -68.678 -39.303 -1.035  1.00 26.03  ? 352 GLN C NE2 1 
ATOM   9199  N  N   . SER C 1 374 ? -73.466 -40.881 -0.875  1.00 26.73  ? 353 SER C N   1 
ATOM   9200  C  CA  . SER C 1 374 ? -73.413 -42.314 -0.603  1.00 24.10  ? 353 SER C CA  1 
ATOM   9201  C  C   . SER C 1 374 ? -73.268 -43.129 -1.887  1.00 23.68  ? 353 SER C C   1 
ATOM   9202  O  O   . SER C 1 374 ? -72.468 -44.064 -1.948  1.00 26.76  ? 353 SER C O   1 
ATOM   9203  C  CB  . SER C 1 374 ? -74.670 -42.745 0.151   1.00 35.81  ? 353 SER C CB  1 
ATOM   9204  O  OG  . SER C 1 374 ? -74.649 -44.149 0.263   1.00 45.54  ? 353 SER C OG  1 
ATOM   9205  N  N   . GLU C 1 375 ? -74.008 -42.759 -2.942  1.00 24.98  ? 354 GLU C N   1 
ATOM   9206  C  CA  . GLU C 1 375 ? -73.877 -43.467 -4.210  1.00 28.62  ? 354 GLU C CA  1 
ATOM   9207  C  C   . GLU C 1 375 ? -72.531 -43.177 -4.890  1.00 27.02  ? 354 GLU C C   1 
ATOM   9208  O  O   . GLU C 1 375 ? -71.928 -44.073 -5.472  1.00 25.74  ? 354 GLU C O   1 
ATOM   9209  C  CB  . GLU C 1 375 ? -75.042 -43.108 -5.127  1.00 23.65  ? 354 GLU C CB  1 
ATOM   9210  C  CG  . GLU C 1 375 ? -75.199 -44.112 -6.281  1.00 31.30  ? 354 GLU C CG  1 
ATOM   9211  C  CD  . GLU C 1 375 ? -76.326 -43.707 -7.229  1.00 34.65  ? 354 GLU C CD  1 
ATOM   9212  O  OE1 . GLU C 1 375 ? -76.853 -42.599 -7.026  1.00 29.97  ? 354 GLU C OE1 1 
ATOM   9213  O  OE2 . GLU C 1 375 ? -76.684 -44.472 -8.174  1.00 27.80  ? 354 GLU C OE2 1 
ATOM   9214  N  N   . ALA C 1 376 ? -72.025 -41.944 -4.796  1.00 26.90  ? 355 ALA C N   1 
ATOM   9215  C  CA  . ALA C 1 376 ? -70.720 -41.639 -5.394  1.00 22.63  ? 355 ALA C CA  1 
ATOM   9216  C  C   . ALA C 1 376 ? -69.579 -42.420 -4.740  1.00 27.12  ? 355 ALA C C   1 
ATOM   9217  O  O   . ALA C 1 376 ? -68.552 -42.645 -5.393  1.00 26.26  ? 355 ALA C O   1 
ATOM   9218  C  CB  . ALA C 1 376 ? -70.452 -40.126 -5.297  1.00 23.05  ? 355 ALA C CB  1 
ATOM   9219  N  N   . GLU C 1 377 ? -69.738 -42.843 -3.472  1.00 24.28  ? 356 GLU C N   1 
ATOM   9220  C  CA  . GLU C 1 377 ? -68.727 -43.671 -2.811  1.00 29.05  ? 356 GLU C CA  1 
ATOM   9221  C  C   . GLU C 1 377 ? -68.454 -44.955 -3.561  1.00 36.10  ? 356 GLU C C   1 
ATOM   9222  O  O   . GLU C 1 377 ? -67.387 -45.551 -3.391  1.00 34.70  ? 356 GLU C O   1 
ATOM   9223  C  CB  . GLU C 1 377 ? -69.159 -44.072 -1.395  1.00 35.80  ? 356 GLU C CB  1 
ATOM   9224  C  CG  . GLU C 1 377 ? -69.211 -42.975 -0.397  1.00 36.30  ? 356 GLU C CG  1 
ATOM   9225  C  CD  . GLU C 1 377 ? -69.525 -43.477 1.013   1.00 45.07  ? 356 GLU C CD  1 
ATOM   9226  O  OE1 . GLU C 1 377 ? -69.726 -44.699 1.229   1.00 50.37  ? 356 GLU C OE1 1 
ATOM   9227  O  OE2 . GLU C 1 377 ? -69.613 -42.630 1.903   1.00 36.56  ? 356 GLU C OE2 1 
ATOM   9228  N  N   . THR C 1 378 ? -69.423 -45.448 -4.334  1.00 27.38  ? 357 THR C N   1 
ATOM   9229  C  CA  . THR C 1 378 ? -69.187 -46.681 -5.075  1.00 27.13  ? 357 THR C CA  1 
ATOM   9230  C  C   . THR C 1 378 ? -68.195 -46.522 -6.226  1.00 29.98  ? 357 THR C C   1 
ATOM   9231  O  O   . THR C 1 378 ? -67.807 -47.530 -6.811  1.00 25.90  ? 357 THR C O   1 
ATOM   9232  C  CB  . THR C 1 378 ? -70.518 -47.243 -5.612  1.00 26.39  ? 357 THR C CB  1 
ATOM   9233  O  OG1 . THR C 1 378 ? -71.022 -46.383 -6.641  1.00 26.56  ? 357 THR C OG1 1 
ATOM   9234  C  CG2 . THR C 1 378 ? -71.552 -47.339 -4.483  1.00 26.62  ? 357 THR C CG2 1 
ATOM   9235  N  N   . ILE C 1 379 ? -67.792 -45.306 -6.593  1.00 26.87  ? 358 ILE C N   1 
ATOM   9236  C  CA  . ILE C 1 379 ? -66.815 -45.137 -7.668  1.00 25.04  ? 358 ILE C CA  1 
ATOM   9237  C  C   . ILE C 1 379 ? -65.445 -45.323 -7.026  1.00 24.00  ? 358 ILE C C   1 
ATOM   9238  O  O   . ILE C 1 379 ? -65.012 -44.462 -6.260  1.00 25.08  ? 358 ILE C O   1 
ATOM   9239  C  CB  . ILE C 1 379 ? -66.914 -43.764 -8.338  1.00 23.95  ? 358 ILE C CB  1 
ATOM   9240  C  CG1 . ILE C 1 379 ? -68.335 -43.471 -8.856  1.00 26.58  ? 358 ILE C CG1 1 
ATOM   9241  C  CG2 . ILE C 1 379 ? -65.877 -43.677 -9.469  1.00 22.84  ? 358 ILE C CG2 1 
ATOM   9242  C  CD1 . ILE C 1 379 ? -68.589 -41.939 -9.066  1.00 26.18  ? 358 ILE C CD1 1 
ATOM   9243  N  N   . LYS C 1 380 ? -64.783 -46.444 -7.318  1.00 23.06  ? 359 LYS C N   1 
ATOM   9244  C  CA  . LYS C 1 380 ? -63.574 -46.806 -6.578  1.00 26.17  ? 359 LYS C CA  1 
ATOM   9245  C  C   . LYS C 1 380 ? -62.448 -45.782 -6.696  1.00 25.01  ? 359 LYS C C   1 
ATOM   9246  O  O   . LYS C 1 380 ? -61.871 -45.432 -5.659  1.00 25.00  ? 359 LYS C O   1 
ATOM   9247  C  CB  . LYS C 1 380 ? -63.091 -48.180 -7.011  1.00 23.97  ? 359 LYS C CB  1 
ATOM   9248  C  CG  . LYS C 1 380 ? -61.938 -48.690 -6.146  1.00 27.32  ? 359 LYS C CG  1 
ATOM   9249  C  CD  . LYS C 1 380 ? -61.681 -50.153 -6.453  1.00 37.67  ? 359 LYS C CD  1 
ATOM   9250  C  CE  . LYS C 1 380 ? -60.914 -50.794 -5.336  1.00 39.69  ? 359 LYS C CE  1 
ATOM   9251  N  NZ  . LYS C 1 380 ? -60.927 -52.276 -5.476  1.00 48.37  ? 359 LYS C NZ  1 
ATOM   9252  N  N   . PRO C 1 381 ? -62.102 -45.251 -7.872  1.00 23.69  ? 360 PRO C N   1 
ATOM   9253  C  CA  . PRO C 1 381 ? -61.019 -44.247 -7.937  1.00 20.62  ? 360 PRO C CA  1 
ATOM   9254  C  C   . PRO C 1 381 ? -61.437 -42.822 -7.580  1.00 20.98  ? 360 PRO C C   1 
ATOM   9255  O  O   . PRO C 1 381 ? -60.605 -41.904 -7.679  1.00 20.97  ? 360 PRO C O   1 
ATOM   9256  C  CB  . PRO C 1 381 ? -60.570 -44.322 -9.403  1.00 28.26  ? 360 PRO C CB  1 
ATOM   9257  C  CG  . PRO C 1 381 ? -61.846 -44.695 -10.150 1.00 27.84  ? 360 PRO C CG  1 
ATOM   9258  C  CD  . PRO C 1 381 ? -62.619 -45.598 -9.213  1.00 26.32  ? 360 PRO C CD  1 
ATOM   9259  N  N   . PHE C 1 382 ? -62.692 -42.579 -7.200  1.00 22.09  ? 361 PHE C N   1 
ATOM   9260  C  CA  . PHE C 1 382 ? -63.123 -41.227 -6.814  1.00 19.95  ? 361 PHE C CA  1 
ATOM   9261  C  C   . PHE C 1 382 ? -62.776 -41.037 -5.334  1.00 24.33  ? 361 PHE C C   1 
ATOM   9262  O  O   . PHE C 1 382 ? -63.599 -41.249 -4.436  1.00 23.43  ? 361 PHE C O   1 
ATOM   9263  C  CB  . PHE C 1 382 ? -64.619 -41.042 -7.086  1.00 20.74  ? 361 PHE C CB  1 
ATOM   9264  C  CG  . PHE C 1 382 ? -65.112 -39.637 -6.850  1.00 21.91  ? 361 PHE C CG  1 
ATOM   9265  C  CD1 . PHE C 1 382 ? -64.356 -38.543 -7.237  1.00 20.09  ? 361 PHE C CD1 1 
ATOM   9266  C  CD2 . PHE C 1 382 ? -66.336 -39.420 -6.254  1.00 20.60  ? 361 PHE C CD2 1 
ATOM   9267  C  CE1 . PHE C 1 382 ? -64.821 -37.251 -7.006  1.00 18.35  ? 361 PHE C CE1 1 
ATOM   9268  C  CE2 . PHE C 1 382 ? -66.820 -38.143 -6.040  1.00 25.26  ? 361 PHE C CE2 1 
ATOM   9269  C  CZ  . PHE C 1 382 ? -66.049 -37.050 -6.401  1.00 19.13  ? 361 PHE C CZ  1 
ATOM   9270  N  N   . ILE C 1 383 ? -61.521 -40.634 -5.079  1.00 22.90  ? 362 ILE C N   1 
ATOM   9271  C  CA  . ILE C 1 383 ? -61.011 -40.575 -3.705  1.00 23.05  ? 362 ILE C CA  1 
ATOM   9272  C  C   . ILE C 1 383 ? -60.498 -39.192 -3.297  1.00 23.00  ? 362 ILE C C   1 
ATOM   9273  O  O   . ILE C 1 383 ? -59.460 -39.112 -2.619  1.00 24.34  ? 362 ILE C O   1 
ATOM   9274  C  CB  . ILE C 1 383 ? -59.891 -41.612 -3.487  1.00 24.52  ? 362 ILE C CB  1 
ATOM   9275  C  CG1 . ILE C 1 383 ? -58.731 -41.348 -4.487  1.00 19.11  ? 362 ILE C CG1 1 
ATOM   9276  C  CG2 . ILE C 1 383 ? -60.469 -43.041 -3.625  1.00 20.08  ? 362 ILE C CG2 1 
ATOM   9277  C  CD1 . ILE C 1 383 ? -57.382 -42.046 -4.086  1.00 23.26  ? 362 ILE C CD1 1 
ATOM   9278  N  N   . PRO C 1 384 ? -61.188 -38.093 -3.617  1.00 18.87  ? 363 PRO C N   1 
ATOM   9279  C  CA  . PRO C 1 384 ? -60.670 -36.773 -3.201  1.00 21.34  ? 363 PRO C CA  1 
ATOM   9280  C  C   . PRO C 1 384 ? -60.486 -36.674 -1.692  1.00 24.22  ? 363 PRO C C   1 
ATOM   9281  O  O   . PRO C 1 384 ? -59.686 -35.862 -1.220  1.00 21.42  ? 363 PRO C O   1 
ATOM   9282  C  CB  . PRO C 1 384 ? -61.750 -35.791 -3.689  1.00 21.33  ? 363 PRO C CB  1 
ATOM   9283  C  CG  . PRO C 1 384 ? -63.039 -36.676 -3.711  1.00 23.13  ? 363 PRO C CG  1 
ATOM   9284  C  CD  . PRO C 1 384 ? -62.554 -38.007 -4.187  1.00 17.54  ? 363 PRO C CD  1 
ATOM   9285  N  N   . GLN C 1 385 ? -61.226 -37.466 -0.911  1.00 23.80  ? 364 GLN C N   1 
ATOM   9286  C  CA  . GLN C 1 385 ? -61.094 -37.434 0.539   1.00 23.12  ? 364 GLN C CA  1 
ATOM   9287  C  C   . GLN C 1 385 ? -60.840 -38.836 1.072   1.00 22.54  ? 364 GLN C C   1 
ATOM   9288  O  O   . GLN C 1 385 ? -61.249 -39.174 2.191   1.00 24.16  ? 364 GLN C O   1 
ATOM   9289  C  CB  . GLN C 1 385 ? -62.328 -36.770 1.176   1.00 22.56  ? 364 GLN C CB  1 
ATOM   9290  C  CG  . GLN C 1 385 ? -62.570 -35.410 0.474   1.00 20.71  ? 364 GLN C CG  1 
ATOM   9291  C  CD  . GLN C 1 385 ? -63.705 -34.542 0.986   1.00 26.89  ? 364 GLN C CD  1 
ATOM   9292  O  OE1 . GLN C 1 385 ? -64.159 -33.671 0.248   1.00 25.43  ? 364 GLN C OE1 1 
ATOM   9293  N  NE2 . GLN C 1 385 ? -64.129 -34.723 2.242   1.00 20.33  ? 364 GLN C NE2 1 
ATOM   9294  N  N   . GLY C 1 386 ? -60.209 -39.681 0.269   1.00 20.04  ? 365 GLY C N   1 
ATOM   9295  C  CA  . GLY C 1 386 ? -59.850 -41.023 0.683   1.00 20.26  ? 365 GLY C CA  1 
ATOM   9296  C  C   . GLY C 1 386 ? -60.735 -42.094 0.052   1.00 21.86  ? 365 GLY C C   1 
ATOM   9297  O  O   . GLY C 1 386 ? -61.790 -41.829 -0.534  1.00 23.01  ? 365 GLY C O   1 
ATOM   9298  N  N   . GLY C 1 387 ? -60.278 -43.335 0.202   1.00 23.52  ? 366 GLY C N   1 
ATOM   9299  C  CA  . GLY C 1 387 ? -60.963 -44.463 -0.411  1.00 20.97  ? 366 GLY C CA  1 
ATOM   9300  C  C   . GLY C 1 387 ? -61.377 -45.544 0.574   1.00 26.37  ? 366 GLY C C   1 
ATOM   9301  O  O   . GLY C 1 387 ? -61.232 -45.370 1.798   1.00 23.51  ? 366 GLY C O   1 
ATOM   9302  N  N   . ALA C 1 388 ? -61.908 -46.651 0.049   1.00 25.42  ? 367 ALA C N   1 
ATOM   9303  C  CA  . ALA C 1 388 ? -62.376 -47.782 0.873   1.00 25.85  ? 367 ALA C CA  1 
ATOM   9304  C  C   . ALA C 1 388 ? -63.508 -47.289 1.780   1.00 28.81  ? 367 ALA C C   1 
ATOM   9305  O  O   . ALA C 1 388 ? -64.304 -46.435 1.370   1.00 27.27  ? 367 ALA C O   1 
ATOM   9306  C  CB  . ALA C 1 388 ? -61.195 -48.425 1.605   1.00 24.68  ? 367 ALA C CB  1 
ATOM   9307  N  N   . ASP C 1 389 ? -63.619 -47.815 3.008   1.00 26.50  ? 368 ASP C N   1 
ATOM   9308  C  CA  . ASP C 1 389 ? -64.826 -47.671 3.818   1.00 27.21  ? 368 ASP C CA  1 
ATOM   9309  C  C   . ASP C 1 389 ? -64.661 -46.660 4.959   1.00 26.83  ? 368 ASP C C   1 
ATOM   9310  O  O   . ASP C 1 389 ? -63.644 -46.649 5.671   1.00 26.71  ? 368 ASP C O   1 
ATOM   9311  C  CB  . ASP C 1 389 ? -65.239 -49.033 4.380   1.00 31.73  ? 368 ASP C CB  1 
ATOM   9312  C  CG  . ASP C 1 389 ? -66.587 -48.989 5.080   1.00 43.17  ? 368 ASP C CG  1 
ATOM   9313  O  OD1 . ASP C 1 389 ? -67.626 -48.956 4.380   1.00 52.42  ? 368 ASP C OD1 1 
ATOM   9314  O  OD2 . ASP C 1 389 ? -66.595 -48.966 6.331   1.00 43.62  ? 368 ASP C OD2 1 
ATOM   9315  N  N   . VAL C 1 390 ? -65.686 -45.823 5.143   1.00 25.57  ? 369 VAL C N   1 
ATOM   9316  C  CA  . VAL C 1 390 ? -65.622 -44.757 6.149   1.00 31.03  ? 369 VAL C CA  1 
ATOM   9317  C  C   . VAL C 1 390 ? -65.522 -45.328 7.562   1.00 34.59  ? 369 VAL C C   1 
ATOM   9318  O  O   . VAL C 1 390 ? -64.735 -44.855 8.385   1.00 30.05  ? 369 VAL C O   1 
ATOM   9319  C  CB  . VAL C 1 390 ? -66.834 -43.820 6.022   1.00 28.24  ? 369 VAL C CB  1 
ATOM   9320  C  CG1 . VAL C 1 390 ? -66.903 -42.890 7.212   1.00 26.99  ? 369 VAL C CG1 1 
ATOM   9321  C  CG2 . VAL C 1 390 ? -66.761 -43.027 4.699   1.00 28.38  ? 369 VAL C CG2 1 
ATOM   9322  N  N   . ARG C 1 391 ? -66.368 -46.298 7.896   1.00 31.65  ? 370 ARG C N   1 
ATOM   9323  C  CA  . ARG C 1 391 ? -66.428 -46.707 9.295   1.00 31.44  ? 370 ARG C CA  1 
ATOM   9324  C  C   . ARG C 1 391 ? -65.310 -47.681 9.659   1.00 34.05  ? 370 ARG C C   1 
ATOM   9325  O  O   . ARG C 1 391 ? -64.799 -47.639 10.784  1.00 36.35  ? 370 ARG C O   1 
ATOM   9326  C  CB  . ARG C 1 391 ? -67.798 -47.327 9.604   1.00 36.88  ? 370 ARG C CB  1 
ATOM   9327  C  CG  . ARG C 1 391 ? -68.972 -46.481 9.097   1.00 44.06  ? 370 ARG C CG  1 
ATOM   9328  C  CD  . ARG C 1 391 ? -70.274 -47.276 9.107   1.00 56.60  ? 370 ARG C CD  1 
ATOM   9329  N  NE  . ARG C 1 391 ? -71.429 -46.493 8.673   1.00 46.71  ? 370 ARG C NE  1 
ATOM   9330  C  CZ  . ARG C 1 391 ? -72.025 -45.574 9.420   1.00 51.64  ? 370 ARG C CZ  1 
ATOM   9331  N  NH1 . ARG C 1 391 ? -71.561 -45.251 10.619  1.00 59.99  ? 370 ARG C NH1 1 
ATOM   9332  N  NH2 . ARG C 1 391 ? -73.117 -44.969 8.956   1.00 63.34  ? 370 ARG C NH2 1 
ATOM   9333  N  N   . THR C 1 392 ? -64.917 -48.568 8.741   1.00 30.44  ? 371 THR C N   1 
ATOM   9334  C  CA  . THR C 1 392 ? -63.906 -49.569 9.075   1.00 34.36  ? 371 THR C CA  1 
ATOM   9335  C  C   . THR C 1 392 ? -62.490 -49.128 8.746   1.00 39.20  ? 371 THR C C   1 
ATOM   9336  O  O   . THR C 1 392 ? -61.543 -49.845 9.095   1.00 36.76  ? 371 THR C O   1 
ATOM   9337  C  CB  . THR C 1 392 ? -64.172 -50.888 8.349   1.00 39.88  ? 371 THR C CB  1 
ATOM   9338  O  OG1 . THR C 1 392 ? -64.118 -50.668 6.935   1.00 43.36  ? 371 THR C OG1 1 
ATOM   9339  C  CG2 . THR C 1 392 ? -65.534 -51.430 8.718   1.00 38.84  ? 371 THR C CG2 1 
ATOM   9340  N  N   . GLY C 1 393 ? -62.312 -47.990 8.069   1.00 31.17  ? 372 GLY C N   1 
ATOM   9341  C  CA  . GLY C 1 393 ? -60.957 -47.558 7.749   1.00 25.85  ? 372 GLY C CA  1 
ATOM   9342  C  C   . GLY C 1 393 ? -60.761 -46.088 8.029   1.00 29.89  ? 372 GLY C C   1 
ATOM   9343  O  O   . GLY C 1 393 ? -61.498 -45.522 8.839   1.00 26.88  ? 372 GLY C O   1 
ATOM   9344  N  N   . HIS C 1 394 ? -59.778 -45.451 7.388   1.00 25.92  ? 373 HIS C N   1 
ATOM   9345  C  CA  . HIS C 1 394 ? -59.433 -44.074 7.710   1.00 25.03  ? 373 HIS C CA  1 
ATOM   9346  C  C   . HIS C 1 394 ? -60.067 -43.047 6.770   1.00 24.45  ? 373 HIS C C   1 
ATOM   9347  O  O   . HIS C 1 394 ? -59.789 -41.853 6.908   1.00 24.05  ? 373 HIS C O   1 
ATOM   9348  C  CB  . HIS C 1 394 ? -57.887 -43.894 7.719   1.00 23.03  ? 373 HIS C CB  1 
ATOM   9349  C  CG  . HIS C 1 394 ? -57.221 -44.301 9.006   1.00 28.99  ? 373 HIS C CG  1 
ATOM   9350  N  ND1 . HIS C 1 394 ? -57.044 -43.433 10.068  1.00 26.63  ? 373 HIS C ND1 1 
ATOM   9351  C  CD2 . HIS C 1 394 ? -56.638 -45.471 9.376   1.00 27.35  ? 373 HIS C CD2 1 
ATOM   9352  C  CE1 . HIS C 1 394 ? -56.401 -44.057 11.042  1.00 24.45  ? 373 HIS C CE1 1 
ATOM   9353  N  NE2 . HIS C 1 394 ? -56.151 -45.293 10.651  1.00 29.41  ? 373 HIS C NE2 1 
ATOM   9354  N  N   . ARG C 1 395 ? -60.880 -43.475 5.805   1.00 22.19  ? 374 ARG C N   1 
ATOM   9355  C  CA  . ARG C 1 395 ? -61.505 -42.527 4.884   1.00 23.22  ? 374 ARG C CA  1 
ATOM   9356  C  C   . ARG C 1 395 ? -62.247 -41.420 5.621   1.00 23.43  ? 374 ARG C C   1 
ATOM   9357  O  O   . ARG C 1 395 ? -62.868 -41.659 6.660   1.00 25.28  ? 374 ARG C O   1 
ATOM   9358  C  CB  . ARG C 1 395 ? -62.490 -43.269 3.976   1.00 23.14  ? 374 ARG C CB  1 
ATOM   9359  C  CG  . ARG C 1 395 ? -63.230 -42.364 3.001   1.00 23.00  ? 374 ARG C CG  1 
ATOM   9360  C  CD  . ARG C 1 395 ? -64.018 -43.278 2.047   1.00 26.37  ? 374 ARG C CD  1 
ATOM   9361  N  NE  . ARG C 1 395 ? -64.720 -42.509 1.035   1.00 22.48  ? 374 ARG C NE  1 
ATOM   9362  C  CZ  . ARG C 1 395 ? -64.920 -42.932 -0.199  1.00 27.47  ? 374 ARG C CZ  1 
ATOM   9363  N  NH1 . ARG C 1 395 ? -64.612 -44.177 -0.560  1.00 23.80  ? 374 ARG C NH1 1 
ATOM   9364  N  NH2 . ARG C 1 395 ? -65.427 -42.086 -1.093  1.00 23.83  ? 374 ARG C NH2 1 
ATOM   9365  N  N   . CYS C 1 396 ? -62.216 -40.221 5.019   1.00 20.53  ? 375 CYS C N   1 
ATOM   9366  C  CA  . CYS C 1 396 ? -62.935 -39.056 5.503   1.00 20.58  ? 375 CYS C CA  1 
ATOM   9367  C  C   . CYS C 1 396 ? -64.383 -39.397 5.853   1.00 22.67  ? 375 CYS C C   1 
ATOM   9368  O  O   . CYS C 1 396 ? -65.116 -39.939 4.998   1.00 24.69  ? 375 CYS C O   1 
ATOM   9369  C  CB  . CYS C 1 396 ? -62.934 -37.945 4.435   1.00 22.86  ? 375 CYS C CB  1 
ATOM   9370  S  SG  . CYS C 1 396 ? -63.639 -36.402 5.022   1.00 23.79  ? 375 CYS C SG  1 
ATOM   9371  N  N   . PRO C 1 397 ? -64.845 -39.077 7.065   1.00 22.07  ? 376 PRO C N   1 
ATOM   9372  C  CA  . PRO C 1 397 ? -66.280 -39.186 7.369   1.00 23.87  ? 376 PRO C CA  1 
ATOM   9373  C  C   . PRO C 1 397 ? -67.054 -37.923 7.037   1.00 24.39  ? 376 PRO C C   1 
ATOM   9374  O  O   . PRO C 1 397 ? -68.267 -37.878 7.284   1.00 26.57  ? 376 PRO C O   1 
ATOM   9375  C  CB  . PRO C 1 397 ? -66.283 -39.428 8.885   1.00 25.93  ? 376 PRO C CB  1 
ATOM   9376  C  CG  . PRO C 1 397 ? -65.157 -38.558 9.368   1.00 24.49  ? 376 PRO C CG  1 
ATOM   9377  C  CD  . PRO C 1 397 ? -64.076 -38.639 8.245   1.00 26.54  ? 376 PRO C CD  1 
ATOM   9378  N  N   . GLY C 1 398 ? -66.391 -36.914 6.463   1.00 22.58  ? 377 GLY C N   1 
ATOM   9379  C  CA  . GLY C 1 398 ? -67.043 -35.632 6.294   1.00 22.42  ? 377 GLY C CA  1 
ATOM   9380  C  C   . GLY C 1 398 ? -67.433 -35.344 4.858   1.00 23.26  ? 377 GLY C C   1 
ATOM   9381  O  O   . GLY C 1 398 ? -67.710 -34.190 4.512   1.00 23.43  ? 377 GLY C O   1 
ATOM   9382  N  N   . GLU C 1 399 ? -67.450 -36.367 4.002   1.00 24.17  ? 378 GLU C N   1 
ATOM   9383  C  CA  . GLU C 1 399 ? -67.724 -36.099 2.587   1.00 21.58  ? 378 GLU C CA  1 
ATOM   9384  C  C   . GLU C 1 399 ? -69.161 -35.633 2.360   1.00 22.55  ? 378 GLU C C   1 
ATOM   9385  O  O   . GLU C 1 399 ? -69.419 -34.824 1.460   1.00 22.37  ? 378 GLU C O   1 
ATOM   9386  C  CB  . GLU C 1 399 ? -67.432 -37.335 1.728   1.00 26.39  ? 378 GLU C CB  1 
ATOM   9387  C  CG  . GLU C 1 399 ? -65.935 -37.710 1.665   1.00 25.21  ? 378 GLU C CG  1 
ATOM   9388  C  CD  . GLU C 1 399 ? -65.640 -38.639 0.497   1.00 26.38  ? 378 GLU C CD  1 
ATOM   9389  O  OE1 . GLU C 1 399 ? -65.770 -39.855 0.674   1.00 30.25  ? 378 GLU C OE1 1 
ATOM   9390  O  OE2 . GLU C 1 399 ? -65.293 -38.136 -0.603  1.00 27.63  ? 378 GLU C OE2 1 
ATOM   9391  N  N   . LYS C 1 400 ? -70.129 -36.155 3.113   1.00 21.59  ? 379 LYS C N   1 
ATOM   9392  C  CA  . LYS C 1 400 ? -71.496 -35.651 2.933   1.00 20.84  ? 379 LYS C CA  1 
ATOM   9393  C  C   . LYS C 1 400 ? -71.599 -34.183 3.333   1.00 26.16  ? 379 LYS C C   1 
ATOM   9394  O  O   . LYS C 1 400 ? -72.253 -33.376 2.650   1.00 24.49  ? 379 LYS C O   1 
ATOM   9395  C  CB  . LYS C 1 400 ? -72.485 -36.496 3.736   1.00 22.80  ? 379 LYS C CB  1 
ATOM   9396  C  CG  . LYS C 1 400 ? -72.582 -37.944 3.236   1.00 22.52  ? 379 LYS C CG  1 
ATOM   9397  C  CD  . LYS C 1 400 ? -73.451 -38.733 4.240   1.00 27.56  ? 379 LYS C CD  1 
ATOM   9398  C  CE  . LYS C 1 400 ? -73.453 -40.217 3.914   1.00 25.65  ? 379 LYS C CE  1 
ATOM   9399  N  NZ  . LYS C 1 400 ? -74.148 -40.971 5.014   1.00 28.18  ? 379 LYS C NZ  1 
ATOM   9400  N  N   . ILE C 1 401 ? -70.923 -33.810 4.416   1.00 26.18  ? 380 ILE C N   1 
ATOM   9401  C  CA  . ILE C 1 401 ? -70.891 -32.414 4.835   1.00 24.53  ? 380 ILE C CA  1 
ATOM   9402  C  C   . ILE C 1 401 ? -70.206 -31.564 3.775   1.00 24.46  ? 380 ILE C C   1 
ATOM   9403  O  O   . ILE C 1 401 ? -70.718 -30.512 3.391   1.00 21.07  ? 380 ILE C O   1 
ATOM   9404  C  CB  . ILE C 1 401 ? -70.177 -32.263 6.188   1.00 28.06  ? 380 ILE C CB  1 
ATOM   9405  C  CG1 . ILE C 1 401 ? -70.950 -32.944 7.339   1.00 28.33  ? 380 ILE C CG1 1 
ATOM   9406  C  CG2 . ILE C 1 401 ? -69.850 -30.747 6.447   1.00 23.10  ? 380 ILE C CG2 1 
ATOM   9407  C  CD1 . ILE C 1 401 ? -72.156 -32.160 7.779   1.00 43.60  ? 380 ILE C CD1 1 
ATOM   9408  N  N   . ALA C 1 402 ? -69.020 -31.999 3.313   1.00 22.21  ? 381 ALA C N   1 
ATOM   9409  C  CA  . ALA C 1 402 ? -68.269 -31.237 2.310   1.00 21.85  ? 381 ALA C CA  1 
ATOM   9410  C  C   . ALA C 1 402 ? -69.087 -31.021 1.038   1.00 23.68  ? 381 ALA C C   1 
ATOM   9411  O  O   . ALA C 1 402 ? -69.109 -29.916 0.476   1.00 22.80  ? 381 ALA C O   1 
ATOM   9412  C  CB  . ALA C 1 402 ? -66.961 -31.957 1.980   1.00 22.13  ? 381 ALA C CB  1 
ATOM   9413  N  N   . VAL C 1 403 ? -69.754 -32.076 0.552   1.00 25.88  ? 382 VAL C N   1 
ATOM   9414  C  CA  . VAL C 1 403 ? -70.512 -31.933 -0.688  1.00 21.93  ? 382 VAL C CA  1 
ATOM   9415  C  C   . VAL C 1 403 ? -71.739 -31.073 -0.452  1.00 23.46  ? 382 VAL C C   1 
ATOM   9416  O  O   . VAL C 1 403 ? -72.163 -30.333 -1.335  1.00 24.26  ? 382 VAL C O   1 
ATOM   9417  C  CB  . VAL C 1 403 ? -70.865 -33.318 -1.264  1.00 23.44  ? 382 VAL C CB  1 
ATOM   9418  C  CG1 . VAL C 1 403 ? -71.870 -33.198 -2.399  1.00 25.90  ? 382 VAL C CG1 1 
ATOM   9419  C  CG2 . VAL C 1 403 ? -69.602 -33.951 -1.836  1.00 24.60  ? 382 VAL C CG2 1 
ATOM   9420  N  N   . THR C 1 404 ? -72.319 -31.132 0.748   1.00 23.69  ? 383 THR C N   1 
ATOM   9421  C  CA  . THR C 1 404 ? -73.427 -30.238 1.043   1.00 24.57  ? 383 THR C CA  1 
ATOM   9422  C  C   . THR C 1 404 ? -72.984 -28.786 1.019   1.00 26.75  ? 383 THR C C   1 
ATOM   9423  O  O   . THR C 1 404 ? -73.647 -27.925 0.426   1.00 24.17  ? 383 THR C O   1 
ATOM   9424  C  CB  . THR C 1 404 ? -74.034 -30.596 2.397   1.00 26.79  ? 383 THR C CB  1 
ATOM   9425  O  OG1 . THR C 1 404 ? -74.555 -31.941 2.316   1.00 27.79  ? 383 THR C OG1 1 
ATOM   9426  C  CG2 . THR C 1 404 ? -75.150 -29.598 2.713   1.00 22.84  ? 383 THR C CG2 1 
ATOM   9427  N  N   . ALA C 1 405 ? -71.851 -28.498 1.661   1.00 23.96  ? 384 ALA C N   1 
ATOM   9428  C  CA  . ALA C 1 405 ? -71.350 -27.131 1.679   1.00 26.42  ? 384 ALA C CA  1 
ATOM   9429  C  C   . ALA C 1 405 ? -70.963 -26.680 0.280   1.00 28.23  ? 384 ALA C C   1 
ATOM   9430  O  O   . ALA C 1 405 ? -71.277 -25.560 -0.113  1.00 20.64  ? 384 ALA C O   1 
ATOM   9431  C  CB  . ALA C 1 405 ? -70.142 -27.016 2.609   1.00 21.98  ? 384 ALA C CB  1 
ATOM   9432  N  N   . LEU C 1 406 ? -70.285 -27.542 -0.491  1.00 24.38  ? 385 LEU C N   1 
ATOM   9433  C  CA  . LEU C 1 406 ? -69.798 -27.110 -1.802  1.00 21.27  ? 385 LEU C CA  1 
ATOM   9434  C  C   . LEU C 1 406 ? -70.954 -26.924 -2.782  1.00 24.48  ? 385 LEU C C   1 
ATOM   9435  O  O   . LEU C 1 406 ? -70.955 -25.978 -3.588  1.00 22.52  ? 385 LEU C O   1 
ATOM   9436  C  CB  . LEU C 1 406 ? -68.764 -28.132 -2.330  1.00 19.04  ? 385 LEU C CB  1 
ATOM   9437  C  CG  . LEU C 1 406 ? -68.121 -27.805 -3.677  1.00 17.73  ? 385 LEU C CG  1 
ATOM   9438  C  CD1 . LEU C 1 406 ? -67.347 -26.485 -3.600  1.00 21.58  ? 385 LEU C CD1 1 
ATOM   9439  C  CD2 . LEU C 1 406 ? -67.140 -28.943 -4.034  1.00 20.50  ? 385 LEU C CD2 1 
ATOM   9440  N  N   . SER C 1 407 ? -71.963 -27.800 -2.704  1.00 23.14  ? 386 SER C N   1 
ATOM   9441  C  CA  . SER C 1 407 ? -73.170 -27.641 -3.518  1.00 21.84  ? 386 SER C CA  1 
ATOM   9442  C  C   . SER C 1 407 ? -73.869 -26.320 -3.238  1.00 24.65  ? 386 SER C C   1 
ATOM   9443  O  O   . SER C 1 407 ? -74.330 -25.634 -4.168  1.00 24.83  ? 386 SER C O   1 
ATOM   9444  C  CB  . SER C 1 407 ? -74.143 -28.807 -3.252  1.00 21.69  ? 386 SER C CB  1 
ATOM   9445  O  OG  . SER C 1 407 ? -73.623 -29.992 -3.813  1.00 34.25  ? 386 SER C OG  1 
ATOM   9446  N  N   . ALA C 1 408 ? -73.975 -25.948 -1.962  1.00 22.36  ? 387 ALA C N   1 
ATOM   9447  C  CA  . ALA C 1 408 ? -74.594 -24.663 -1.637  1.00 26.10  ? 387 ALA C CA  1 
ATOM   9448  C  C   . ALA C 1 408 ? -73.783 -23.499 -2.208  1.00 24.17  ? 387 ALA C C   1 
ATOM   9449  O  O   . ALA C 1 408 ? -74.354 -22.496 -2.649  1.00 26.43  ? 387 ALA C O   1 
ATOM   9450  C  CB  . ALA C 1 408 ? -74.747 -24.518 -0.130  1.00 26.64  ? 387 ALA C CB  1 
ATOM   9451  N  N   . ALA C 1 409 ? -72.446 -23.601 -2.190  1.00 25.72  ? 388 ALA C N   1 
ATOM   9452  C  CA  . ALA C 1 409 ? -71.643 -22.538 -2.791  1.00 25.53  ? 388 ALA C CA  1 
ATOM   9453  C  C   . ALA C 1 409 ? -71.823 -22.500 -4.301  1.00 21.73  ? 388 ALA C C   1 
ATOM   9454  O  O   . ALA C 1 409 ? -71.951 -21.413 -4.894  1.00 22.62  ? 388 ALA C O   1 
ATOM   9455  C  CB  . ALA C 1 409 ? -70.166 -22.716 -2.426  1.00 25.54  ? 388 ALA C CB  1 
ATOM   9456  N  N   . VAL C 1 410 ? -71.849 -23.676 -4.946  1.00 23.49  ? 389 VAL C N   1 
ATOM   9457  C  CA  . VAL C 1 410 ? -72.026 -23.722 -6.400  1.00 21.93  ? 389 VAL C CA  1 
ATOM   9458  C  C   . VAL C 1 410 ? -73.350 -23.072 -6.799  1.00 26.62  ? 389 VAL C C   1 
ATOM   9459  O  O   . VAL C 1 410 ? -73.419 -22.285 -7.756  1.00 25.70  ? 389 VAL C O   1 
ATOM   9460  C  CB  . VAL C 1 410 ? -71.956 -25.176 -6.904  1.00 26.11  ? 389 VAL C CB  1 
ATOM   9461  C  CG1 . VAL C 1 410 ? -72.518 -25.281 -8.343  1.00 23.22  ? 389 VAL C CG1 1 
ATOM   9462  C  CG2 . VAL C 1 410 ? -70.503 -25.728 -6.865  1.00 25.88  ? 389 VAL C CG2 1 
ATOM   9463  N  N   . GLU C 1 411 ? -74.429 -23.403 -6.082  1.00 23.44  ? 390 GLU C N   1 
ATOM   9464  C  CA  . GLU C 1 411 ? -75.725 -22.812 -6.437  1.00 25.76  ? 390 GLU C CA  1 
ATOM   9465  C  C   . GLU C 1 411 ? -75.700 -21.296 -6.327  1.00 26.22  ? 390 GLU C C   1 
ATOM   9466  O  O   . GLU C 1 411 ? -76.269 -20.592 -7.175  1.00 27.40  ? 390 GLU C O   1 
ATOM   9467  C  CB  . GLU C 1 411 ? -76.844 -23.423 -5.578  1.00 29.23  ? 390 GLU C CB  1 
ATOM   9468  C  CG  . GLU C 1 411 ? -77.495 -24.575 -6.334  1.00 44.08  ? 390 GLU C CG  1 
ATOM   9469  C  CD  . GLU C 1 411 ? -78.389 -25.443 -5.475  1.00 57.55  ? 390 GLU C CD  1 
ATOM   9470  O  OE1 . GLU C 1 411 ? -78.733 -25.037 -4.342  1.00 58.05  ? 390 GLU C OE1 1 
ATOM   9471  O  OE2 . GLU C 1 411 ? -78.746 -26.539 -5.943  1.00 47.39  ? 390 GLU C OE2 1 
ATOM   9472  N  N   . ALA C 1 412 ? -75.020 -20.767 -5.311  1.00 27.79  ? 391 ALA C N   1 
ATOM   9473  C  CA  . ALA C 1 412 ? -75.021 -19.325 -5.104  1.00 28.49  ? 391 ALA C CA  1 
ATOM   9474  C  C   . ALA C 1 412 ? -74.074 -18.621 -6.070  1.00 21.98  ? 391 ALA C C   1 
ATOM   9475  O  O   . ALA C 1 412 ? -74.406 -17.558 -6.610  1.00 29.42  ? 391 ALA C O   1 
ATOM   9476  C  CB  . ALA C 1 412 ? -74.648 -19.027 -3.656  1.00 25.13  ? 391 ALA C CB  1 
ATOM   9477  N  N   . LEU C 1 413 ? -72.906 -19.216 -6.324  1.00 22.26  ? 392 LEU C N   1 
ATOM   9478  C  CA  . LEU C 1 413 ? -71.945 -18.604 -7.245  1.00 23.87  ? 392 LEU C CA  1 
ATOM   9479  C  C   . LEU C 1 413 ? -72.486 -18.586 -8.665  1.00 27.38  ? 392 LEU C C   1 
ATOM   9480  O  O   . LEU C 1 413 ? -72.124 -17.709 -9.462  1.00 26.57  ? 392 LEU C O   1 
ATOM   9481  C  CB  . LEU C 1 413 ? -70.605 -19.374 -7.186  1.00 22.77  ? 392 LEU C CB  1 
ATOM   9482  C  CG  . LEU C 1 413 ? -69.860 -19.270 -5.845  1.00 26.18  ? 392 LEU C CG  1 
ATOM   9483  C  CD1 . LEU C 1 413 ? -68.799 -20.394 -5.658  1.00 24.07  ? 392 LEU C CD1 1 
ATOM   9484  C  CD2 . LEU C 1 413 ? -69.169 -17.905 -5.756  1.00 24.49  ? 392 LEU C CD2 1 
ATOM   9485  N  N   . ALA C 1 414 ? -73.354 -19.543 -9.007  1.00 26.26  ? 393 ALA C N   1 
ATOM   9486  C  CA  . ALA C 1 414 ? -73.792 -19.644 -10.391 1.00 24.49  ? 393 ALA C CA  1 
ATOM   9487  C  C   . ALA C 1 414 ? -74.752 -18.532 -10.773 1.00 25.47  ? 393 ALA C C   1 
ATOM   9488  O  O   . ALA C 1 414 ? -74.904 -18.246 -11.963 1.00 27.66  ? 393 ALA C O   1 
ATOM   9489  C  CB  . ALA C 1 414 ? -74.467 -20.995 -10.637 1.00 26.23  ? 393 ALA C CB  1 
ATOM   9490  N  N   . ARG C 1 415 ? -75.409 -17.912 -9.810  1.00 27.40  ? 394 ARG C N   1 
ATOM   9491  C  CA  . ARG C 1 415 ? -76.433 -16.925 -10.143 1.00 31.07  ? 394 ARG C CA  1 
ATOM   9492  C  C   . ARG C 1 415 ? -75.836 -15.804 -10.994 1.00 30.73  ? 394 ARG C C   1 
ATOM   9493  O  O   . ARG C 1 415 ? -74.705 -15.370 -10.737 1.00 29.09  ? 394 ARG C O   1 
ATOM   9494  C  CB  . ARG C 1 415 ? -77.049 -16.361 -8.866  1.00 31.09  ? 394 ARG C CB  1 
ATOM   9495  C  CG  . ARG C 1 415 ? -77.799 -17.470 -8.109  1.00 30.96  ? 394 ARG C CG  1 
ATOM   9496  C  CD  . ARG C 1 415 ? -78.922 -16.930 -7.262  1.00 55.00  ? 394 ARG C CD  1 
ATOM   9497  N  NE  . ARG C 1 415 ? -78.444 -16.590 -5.930  1.00 57.20  ? 394 ARG C NE  1 
ATOM   9498  C  CZ  . ARG C 1 415 ? -78.493 -17.413 -4.893  1.00 51.36  ? 394 ARG C CZ  1 
ATOM   9499  N  NH1 . ARG C 1 415 ? -79.023 -18.625 -4.998  1.00 54.52  ? 394 ARG C NH1 1 
ATOM   9500  N  NH2 . ARG C 1 415 ? -78.006 -17.007 -3.723  1.00 54.34  ? 394 ARG C NH2 1 
ATOM   9501  N  N   . PRO C 1 416 ? -76.555 -15.328 -12.019 1.00 30.02  ? 395 PRO C N   1 
ATOM   9502  C  CA  . PRO C 1 416 ? -75.934 -14.410 -12.998 1.00 32.46  ? 395 PRO C CA  1 
ATOM   9503  C  C   . PRO C 1 416 ? -75.508 -13.066 -12.420 1.00 35.97  ? 395 PRO C C   1 
ATOM   9504  O  O   . PRO C 1 416 ? -74.644 -12.405 -13.014 1.00 33.96  ? 395 PRO C O   1 
ATOM   9505  C  CB  . PRO C 1 416 ? -77.022 -14.250 -14.075 1.00 34.60  ? 395 PRO C CB  1 
ATOM   9506  C  CG  . PRO C 1 416 ? -78.295 -14.604 -13.398 1.00 34.39  ? 395 PRO C CG  1 
ATOM   9507  C  CD  . PRO C 1 416 ? -77.947 -15.658 -12.377 1.00 32.39  ? 395 PRO C CD  1 
ATOM   9508  N  N   . GLU C 1 417 ? -76.026 -12.668 -11.258 1.00 26.84  ? 396 GLU C N   1 
ATOM   9509  C  CA  . GLU C 1 417 ? -75.612 -11.407 -10.653 1.00 30.97  ? 396 GLU C CA  1 
ATOM   9510  C  C   . GLU C 1 417 ? -74.225 -11.488 -10.014 1.00 37.82  ? 396 GLU C C   1 
ATOM   9511  O  O   . GLU C 1 417 ? -73.622 -10.453 -9.724  1.00 31.48  ? 396 GLU C O   1 
ATOM   9512  C  CB  . GLU C 1 417 ? -76.660 -10.979 -9.627  1.00 29.97  ? 396 GLU C CB  1 
ATOM   9513  C  CG  . GLU C 1 417 ? -77.055 -12.090 -8.663  1.00 49.20  ? 396 GLU C CG  1 
ATOM   9514  C  CD  . GLU C 1 417 ? -78.353 -12.840 -9.048  1.00 53.90  ? 396 GLU C CD  1 
ATOM   9515  O  OE1 . GLU C 1 417 ? -78.629 -13.087 -10.249 1.00 45.83  ? 396 GLU C OE1 1 
ATOM   9516  O  OE2 . GLU C 1 417 ? -79.109 -13.196 -8.118  1.00 75.54  ? 396 GLU C OE2 1 
ATOM   9517  N  N   . VAL C 1 418 ? -73.701 -12.687 -9.806  1.00 30.24  ? 397 VAL C N   1 
ATOM   9518  C  CA  . VAL C 1 418 ? -72.329 -12.869 -9.342  1.00 27.59  ? 397 VAL C CA  1 
ATOM   9519  C  C   . VAL C 1 418 ? -71.375 -12.670 -10.516 1.00 30.41  ? 397 VAL C C   1 
ATOM   9520  O  O   . VAL C 1 418 ? -71.422 -13.403 -11.509 1.00 31.19  ? 397 VAL C O   1 
ATOM   9521  C  CB  . VAL C 1 418 ? -72.160 -14.258 -8.710  1.00 27.65  ? 397 VAL C CB  1 
ATOM   9522  C  CG1 . VAL C 1 418 ? -70.719 -14.466 -8.219  1.00 30.06  ? 397 VAL C CG1 1 
ATOM   9523  C  CG2 . VAL C 1 418 ? -73.149 -14.413 -7.541  1.00 28.33  ? 397 VAL C CG2 1 
ATOM   9524  N  N   . ARG C 1 419 ? -70.518 -11.668 -10.416 1.00 27.90  ? 398 ARG C N   1 
ATOM   9525  C  CA  . ARG C 1 419 ? -69.550 -11.362 -11.465 1.00 30.66  ? 398 ARG C CA  1 
ATOM   9526  C  C   . ARG C 1 419 ? -68.201 -11.886 -11.003 1.00 27.45  ? 398 ARG C C   1 
ATOM   9527  O  O   . ARG C 1 419 ? -67.626 -11.359 -10.052 1.00 27.94  ? 398 ARG C O   1 
ATOM   9528  C  CB  . ARG C 1 419 ? -69.484 -9.855  -11.727 1.00 30.84  ? 398 ARG C CB  1 
ATOM   9529  C  CG  . ARG C 1 419 ? -70.868 -9.259  -12.072 1.00 39.08  ? 398 ARG C CG  1 
ATOM   9530  C  CD  . ARG C 1 419 ? -71.340 -9.774  -13.415 1.00 48.37  ? 398 ARG C CD  1 
ATOM   9531  N  NE  . ARG C 1 419 ? -72.795 -9.891  -13.495 1.00 58.59  ? 398 ARG C NE  1 
ATOM   9532  C  CZ  . ARG C 1 419 ? -73.606 -8.935  -13.930 1.00 65.71  ? 398 ARG C CZ  1 
ATOM   9533  N  NH1 . ARG C 1 419 ? -73.145 -7.746  -14.291 1.00 58.21  ? 398 ARG C NH1 1 
ATOM   9534  N  NH2 . ARG C 1 419 ? -74.912 -9.180  -14.009 1.00 66.75  ? 398 ARG C NH2 1 
ATOM   9535  N  N   . ILE C 1 420 ? -67.707 -12.926 -11.664 1.00 28.16  ? 399 ILE C N   1 
ATOM   9536  C  CA  . ILE C 1 420 ? -66.454 -13.557 -11.271 1.00 25.94  ? 399 ILE C CA  1 
ATOM   9537  C  C   . ILE C 1 420 ? -65.322 -12.940 -12.086 1.00 25.92  ? 399 ILE C C   1 
ATOM   9538  O  O   . ILE C 1 420 ? -65.356 -12.962 -13.319 1.00 26.99  ? 399 ILE C O   1 
ATOM   9539  C  CB  . ILE C 1 420 ? -66.526 -15.081 -11.461 1.00 26.49  ? 399 ILE C CB  1 
ATOM   9540  C  CG1 . ILE C 1 420 ? -67.724 -15.627 -10.694 1.00 26.81  ? 399 ILE C CG1 1 
ATOM   9541  C  CG2 . ILE C 1 420 ? -65.243 -15.783 -10.950 1.00 26.56  ? 399 ILE C CG2 1 
ATOM   9542  C  CD1 . ILE C 1 420 ? -68.087 -17.091 -11.055 1.00 28.97  ? 399 ILE C CD1 1 
ATOM   9543  N  N   . SER C 1 421 ? -64.301 -12.434 -11.394 1.00 24.23  ? 400 SER C N   1 
ATOM   9544  C  CA  . SER C 1 421 ? -63.148 -11.814 -12.052 1.00 25.57  ? 400 SER C CA  1 
ATOM   9545  C  C   . SER C 1 421 ? -62.420 -12.825 -12.931 1.00 29.67  ? 400 SER C C   1 
ATOM   9546  O  O   . SER C 1 421 ? -62.192 -13.956 -12.518 1.00 26.17  ? 400 SER C O   1 
ATOM   9547  C  CB  . SER C 1 421 ? -62.168 -11.259 -11.001 1.00 25.60  ? 400 SER C CB  1 
ATOM   9548  O  OG  . SER C 1 421 ? -60.938 -10.868 -11.631 1.00 30.19  ? 400 SER C OG  1 
ATOM   9549  N  N   . ALA C 1 422 ? -62.017 -12.397 -14.137 1.00 27.66  ? 401 ALA C N   1 
ATOM   9550  C  CA  . ALA C 1 422 ? -61.330 -13.268 -15.091 1.00 28.21  ? 401 ALA C CA  1 
ATOM   9551  C  C   . ALA C 1 422 ? -59.837 -12.962 -15.181 1.00 24.43  ? 401 ALA C C   1 
ATOM   9552  O  O   . ALA C 1 422 ? -59.143 -13.483 -16.077 1.00 26.79  ? 401 ALA C O   1 
ATOM   9553  C  CB  . ALA C 1 422 ? -61.970 -13.158 -16.477 1.00 31.07  ? 401 ALA C CB  1 
ATOM   9554  N  N   . GLU C 1 423 ? -59.321 -12.134 -14.279 1.00 23.87  ? 402 GLU C N   1 
ATOM   9555  C  CA  . GLU C 1 423 ? -57.917 -11.760 -14.370 1.00 22.25  ? 402 GLU C CA  1 
ATOM   9556  C  C   . GLU C 1 423 ? -57.040 -12.934 -13.957 1.00 27.67  ? 402 GLU C C   1 
ATOM   9557  O  O   . GLU C 1 423 ? -57.475 -13.866 -13.279 1.00 24.62  ? 402 GLU C O   1 
ATOM   9558  C  CB  . GLU C 1 423 ? -57.629 -10.520 -13.499 1.00 28.44  ? 402 GLU C CB  1 
ATOM   9559  C  CG  . GLU C 1 423 ? -58.585 -9.380  -13.821 1.00 25.10  ? 402 GLU C CG  1 
ATOM   9560  C  CD  . GLU C 1 423 ? -57.923 -8.013  -13.855 1.00 42.22  ? 402 GLU C CD  1 
ATOM   9561  O  OE1 . GLU C 1 423 ? -56.669 -7.936  -13.787 1.00 32.39  ? 402 GLU C OE1 1 
ATOM   9562  O  OE2 . GLU C 1 423 ? -58.679 -7.010  -13.954 1.00 37.09  ? 402 GLU C OE2 1 
ATOM   9563  N  N   . ALA C 1 424 ? -55.773 -12.879 -14.369 1.00 25.66  ? 403 ALA C N   1 
ATOM   9564  C  CA  . ALA C 1 424 ? -54.929 -14.059 -14.242 1.00 25.54  ? 403 ALA C CA  1 
ATOM   9565  C  C   . ALA C 1 424 ? -54.746 -14.487 -12.788 1.00 23.38  ? 403 ALA C C   1 
ATOM   9566  O  O   . ALA C 1 424 ? -54.722 -15.687 -12.491 1.00 24.30  ? 403 ALA C O   1 
ATOM   9567  C  CB  . ALA C 1 424 ? -53.573 -13.802 -14.916 1.00 27.34  ? 403 ALA C CB  1 
ATOM   9568  N  N   . ILE C 1 425 ? -54.620 -13.537 -11.855 1.00 20.78  ? 404 ILE C N   1 
ATOM   9569  C  CA  . ILE C 1 425 ? -54.440 -13.964 -10.463 1.00 24.60  ? 404 ILE C CA  1 
ATOM   9570  C  C   . ILE C 1 425 ? -55.695 -14.579 -9.868  1.00 25.89  ? 404 ILE C C   1 
ATOM   9571  O  O   . ILE C 1 425 ? -55.617 -15.277 -8.842  1.00 23.70  ? 404 ILE C O   1 
ATOM   9572  C  CB  . ILE C 1 425 ? -53.953 -12.796 -9.596  1.00 32.73  ? 404 ILE C CB  1 
ATOM   9573  C  CG1 . ILE C 1 425 ? -54.867 -11.593 -9.747  1.00 27.49  ? 404 ILE C CG1 1 
ATOM   9574  C  CG2 . ILE C 1 425 ? -52.527 -12.426 -10.026 1.00 29.37  ? 404 ILE C CG2 1 
ATOM   9575  C  CD1 . ILE C 1 425 ? -54.488 -10.484 -8.764  1.00 29.57  ? 404 ILE C CD1 1 
ATOM   9576  N  N   . ASP C 1 426 ? -56.846 -14.357 -10.497 1.00 24.66  ? 405 ASP C N   1 
ATOM   9577  C  CA  . ASP C 1 426 ? -58.111 -14.918 -10.022 1.00 23.38  ? 405 ASP C CA  1 
ATOM   9578  C  C   . ASP C 1 426 ? -58.393 -16.305 -10.575 1.00 27.07  ? 405 ASP C C   1 
ATOM   9579  O  O   . ASP C 1 426 ? -59.132 -17.083 -9.959  1.00 31.19  ? 405 ASP C O   1 
ATOM   9580  C  CB  . ASP C 1 426 ? -59.267 -14.000 -10.426 1.00 23.78  ? 405 ASP C CB  1 
ATOM   9581  C  CG  . ASP C 1 426 ? -59.166 -12.632 -9.801  1.00 34.79  ? 405 ASP C CG  1 
ATOM   9582  O  OD1 . ASP C 1 426 ? -59.246 -12.543 -8.554  1.00 25.93  ? 405 ASP C OD1 1 
ATOM   9583  O  OD2 . ASP C 1 426 ? -58.982 -11.656 -10.573 1.00 28.26  ? 405 ASP C OD2 1 
ATOM   9584  N  N   . ILE C 1 427 ? -57.857 -16.615 -11.745 1.00 29.21  ? 406 ILE C N   1 
ATOM   9585  C  CA  . ILE C 1 427 ? -58.222 -17.828 -12.453 1.00 24.40  ? 406 ILE C CA  1 
ATOM   9586  C  C   . ILE C 1 427 ? -57.129 -18.888 -12.390 1.00 36.28  ? 406 ILE C C   1 
ATOM   9587  O  O   . ILE C 1 427 ? -57.446 -20.083 -12.375 1.00 38.50  ? 406 ILE C O   1 
ATOM   9588  C  CB  . ILE C 1 427 ? -58.589 -17.515 -13.914 1.00 33.31  ? 406 ILE C CB  1 
ATOM   9589  C  CG1 . ILE C 1 427 ? -59.846 -16.654 -13.973 1.00 25.97  ? 406 ILE C CG1 1 
ATOM   9590  C  CG2 . ILE C 1 427 ? -58.759 -18.815 -14.720 1.00 42.89  ? 406 ILE C CG2 1 
ATOM   9591  C  CD1 . ILE C 1 427 ? -61.058 -17.297 -13.314 1.00 32.12  ? 406 ILE C CD1 1 
ATOM   9592  N  N   . ASN C 1 428 ? -55.856 -18.501 -12.322 1.00 26.40  ? 407 ASN C N   1 
ATOM   9593  C  CA  . ASN C 1 428 ? -54.836 -19.530 -12.407 1.00 23.48  ? 407 ASN C CA  1 
ATOM   9594  C  C   . ASN C 1 428 ? -54.402 -19.935 -11.010 1.00 29.60  ? 407 ASN C C   1 
ATOM   9595  O  O   . ASN C 1 428 ? -54.613 -19.207 -10.043 1.00 28.65  ? 407 ASN C O   1 
ATOM   9596  C  CB  . ASN C 1 428 ? -53.658 -19.026 -13.248 1.00 29.69  ? 407 ASN C CB  1 
ATOM   9597  C  CG  . ASN C 1 428 ? -54.049 -18.840 -14.722 1.00 33.44  ? 407 ASN C CG  1 
ATOM   9598  O  OD1 . ASN C 1 428 ? -54.042 -19.791 -15.483 1.00 31.99  ? 407 ASN C OD1 1 
ATOM   9599  N  ND2 . ASN C 1 428 ? -54.394 -17.620 -15.112 1.00 30.28  ? 407 ASN C ND2 1 
ATOM   9600  N  N   . TYR C 1 429 ? -53.836 -21.135 -10.904 1.00 30.05  ? 408 TYR C N   1 
ATOM   9601  C  CA  . TYR C 1 429 ? -53.344 -21.628 -9.626  1.00 28.07  ? 408 TYR C CA  1 
ATOM   9602  C  C   . TYR C 1 429 ? -52.051 -22.403 -9.860  1.00 29.21  ? 408 TYR C C   1 
ATOM   9603  O  O   . TYR C 1 429 ? -51.866 -23.026 -10.908 1.00 26.10  ? 408 TYR C O   1 
ATOM   9604  C  CB  . TYR C 1 429 ? -54.384 -22.532 -8.921  1.00 25.95  ? 408 TYR C CB  1 
ATOM   9605  C  CG  . TYR C 1 429 ? -54.939 -23.637 -9.774  1.00 22.40  ? 408 TYR C CG  1 
ATOM   9606  C  CD1 . TYR C 1 429 ? -56.009 -23.418 -10.648 1.00 25.39  ? 408 TYR C CD1 1 
ATOM   9607  C  CD2 . TYR C 1 429 ? -54.401 -24.913 -9.721  1.00 21.47  ? 408 TYR C CD2 1 
ATOM   9608  C  CE1 . TYR C 1 429 ? -56.512 -24.447 -11.440 1.00 25.32  ? 408 TYR C CE1 1 
ATOM   9609  C  CE2 . TYR C 1 429 ? -54.923 -25.950 -10.482 1.00 23.56  ? 408 TYR C CE2 1 
ATOM   9610  C  CZ  . TYR C 1 429 ? -55.964 -25.710 -11.353 1.00 29.03  ? 408 TYR C CZ  1 
ATOM   9611  O  OH  . TYR C 1 429 ? -56.449 -26.766 -12.118 1.00 30.93  ? 408 TYR C OH  1 
ATOM   9612  N  N   . SER C 1 430 ? -51.176 -22.368 -8.866  1.00 25.56  ? 409 SER C N   1 
ATOM   9613  C  CA  . SER C 1 430 ? -49.933 -23.128 -8.915  1.00 30.72  ? 409 SER C CA  1 
ATOM   9614  C  C   . SER C 1 430 ? -50.142 -24.574 -8.457  1.00 29.47  ? 409 SER C C   1 
ATOM   9615  O  O   . SER C 1 430 ? -50.942 -24.862 -7.559  1.00 28.94  ? 409 SER C O   1 
ATOM   9616  C  CB  . SER C 1 430 ? -48.881 -22.470 -8.016  1.00 30.23  ? 409 SER C CB  1 
ATOM   9617  O  OG  . SER C 1 430 ? -47.715 -23.273 -7.952  1.00 27.30  ? 409 SER C OG  1 
ATOM   9618  N  N   . MET C 1 431 ? -49.396 -25.487 -9.069  1.00 20.92  ? 410 MET C N   1 
ATOM   9619  C  CA  . MET C 1 431 ? -49.376 -26.879 -8.637  1.00 20.47  ? 410 MET C CA  1 
ATOM   9620  C  C   . MET C 1 431 ? -48.198 -27.187 -7.718  1.00 27.09  ? 410 MET C C   1 
ATOM   9621  O  O   . MET C 1 431 ? -48.049 -28.329 -7.282  1.00 22.71  ? 410 MET C O   1 
ATOM   9622  C  CB  . MET C 1 431 ? -49.347 -27.819 -9.867  1.00 28.43  ? 410 MET C CB  1 
ATOM   9623  C  CG  . MET C 1 431 ? -50.599 -27.762 -10.743 1.00 28.25  ? 410 MET C CG  1 
ATOM   9624  S  SD  . MET C 1 431 ? -51.974 -28.528 -9.900  1.00 36.17  ? 410 MET C SD  1 
ATOM   9625  C  CE  . MET C 1 431 ? -51.733 -30.286 -10.260 1.00 31.33  ? 410 MET C CE  1 
ATOM   9626  N  N   . THR C 1 432 ? -47.331 -26.225 -7.437  1.00 24.27  ? 411 THR C N   1 
ATOM   9627  C  CA  . THR C 1 432 ? -46.121 -26.554 -6.700  1.00 25.68  ? 411 THR C CA  1 
ATOM   9628  C  C   . THR C 1 432 ? -46.179 -26.146 -5.232  1.00 32.16  ? 411 THR C C   1 
ATOM   9629  O  O   . THR C 1 432 ? -45.204 -26.372 -4.516  1.00 33.57  ? 411 THR C O   1 
ATOM   9630  C  CB  . THR C 1 432 ? -44.898 -25.916 -7.378  1.00 29.29  ? 411 THR C CB  1 
ATOM   9631  O  OG1 . THR C 1 432 ? -45.150 -24.531 -7.600  1.00 28.67  ? 411 THR C OG1 1 
ATOM   9632  C  CG2 . THR C 1 432 ? -44.679 -26.565 -8.725  1.00 26.64  ? 411 THR C CG2 1 
ATOM   9633  N  N   . GLU C 1 433 ? -47.289 -25.561 -4.776  1.00 28.16  ? 412 GLU C N   1 
ATOM   9634  C  CA  . GLU C 1 433 ? -47.497 -25.189 -3.379  1.00 28.91  ? 412 GLU C CA  1 
ATOM   9635  C  C   . GLU C 1 433 ? -48.746 -25.880 -2.842  1.00 27.99  ? 412 GLU C C   1 
ATOM   9636  O  O   . GLU C 1 433 ? -49.771 -25.952 -3.528  1.00 26.60  ? 412 GLU C O   1 
ATOM   9637  C  CB  . GLU C 1 433 ? -47.653 -23.659 -3.222  1.00 38.71  ? 412 GLU C CB  1 
ATOM   9638  C  CG  . GLU C 1 433 ? -46.344 -22.848 -3.430  1.00 46.20  ? 412 GLU C CG  1 
ATOM   9639  C  CD  . GLU C 1 433 ? -45.926 -22.645 -4.901  1.00 66.66  ? 412 GLU C CD  1 
ATOM   9640  O  OE1 . GLU C 1 433 ? -46.681 -22.000 -5.684  1.00 44.03  ? 412 GLU C OE1 1 
ATOM   9641  O  OE2 . GLU C 1 433 ? -44.809 -23.110 -5.264  1.00 60.46  ? 412 GLU C OE2 1 
ATOM   9642  N  N   . ILE C 1 434 ? -48.668 -26.344 -1.596  1.00 23.77  ? 413 ILE C N   1 
ATOM   9643  C  CA  . ILE C 1 434 ? -49.761 -27.032 -0.915  1.00 22.64  ? 413 ILE C CA  1 
ATOM   9644  C  C   . ILE C 1 434 ? -50.242 -26.122 0.210   1.00 31.12  ? 413 ILE C C   1 
ATOM   9645  O  O   . ILE C 1 434 ? -49.411 -25.525 0.909   1.00 28.44  ? 413 ILE C O   1 
ATOM   9646  C  CB  . ILE C 1 434 ? -49.260 -28.385 -0.370  1.00 28.32  ? 413 ILE C CB  1 
ATOM   9647  C  CG1 . ILE C 1 434 ? -48.908 -29.305 -1.554  1.00 30.74  ? 413 ILE C CG1 1 
ATOM   9648  C  CG2 . ILE C 1 434 ? -50.277 -28.990 0.578   1.00 37.21  ? 413 ILE C CG2 1 
ATOM   9649  C  CD1 . ILE C 1 434 ? -47.929 -30.410 -1.242  1.00 42.13  ? 413 ILE C CD1 1 
ATOM   9650  N  N   . LEU C 1 435 ? -51.566 -25.960 0.360   1.00 24.70  ? 414 LEU C N   1 
ATOM   9651  C  CA  . LEU C 1 435 ? -52.685 -26.337 -0.488  1.00 22.38  ? 414 LEU C CA  1 
ATOM   9652  C  C   . LEU C 1 435 ? -52.750 -25.379 -1.662  1.00 31.71  ? 414 LEU C C   1 
ATOM   9653  O  O   . LEU C 1 435 ? -52.263 -24.254 -1.574  1.00 32.63  ? 414 LEU C O   1 
ATOM   9654  C  CB  . LEU C 1 435 ? -54.012 -26.270 0.308   1.00 23.63  ? 414 LEU C CB  1 
ATOM   9655  C  CG  . LEU C 1 435 ? -54.091 -27.238 1.482   1.00 26.23  ? 414 LEU C CG  1 
ATOM   9656  C  CD1 . LEU C 1 435 ? -55.336 -26.987 2.357   1.00 23.46  ? 414 LEU C CD1 1 
ATOM   9657  C  CD2 . LEU C 1 435 ? -54.063 -28.713 0.995   1.00 24.65  ? 414 LEU C CD2 1 
ATOM   9658  N  N   . ALA C 1 436 ? -53.365 -25.816 -2.752  1.00 23.00  ? 415 ALA C N   1 
ATOM   9659  C  CA  . ALA C 1 436 ? -53.497 -24.998 -3.961  1.00 23.74  ? 415 ALA C CA  1 
ATOM   9660  C  C   . ALA C 1 436 ? -54.773 -24.147 -3.915  1.00 26.03  ? 415 ALA C C   1 
ATOM   9661  O  O   . ALA C 1 436 ? -55.814 -24.604 -3.442  1.00 25.65  ? 415 ALA C O   1 
ATOM   9662  C  CB  . ALA C 1 436 ? -53.556 -25.913 -5.184  1.00 23.49  ? 415 ALA C CB  1 
ATOM   9663  N  N   . ARG C 1 437 ? -54.681 -22.925 -4.425  1.00 25.54  ? 416 ARG C N   1 
ATOM   9664  C  CA  . ARG C 1 437 ? -55.852 -22.104 -4.722  1.00 27.83  ? 416 ARG C CA  1 
ATOM   9665  C  C   . ARG C 1 437 ? -55.397 -20.941 -5.595  1.00 27.47  ? 416 ARG C C   1 
ATOM   9666  O  O   . ARG C 1 437 ? -54.203 -20.594 -5.602  1.00 26.54  ? 416 ARG C O   1 
ATOM   9667  C  CB  . ARG C 1 437 ? -56.526 -21.579 -3.426  1.00 28.96  ? 416 ARG C CB  1 
ATOM   9668  C  CG  . ARG C 1 437 ? -55.586 -20.729 -2.538  1.00 27.59  ? 416 ARG C CG  1 
ATOM   9669  C  CD  . ARG C 1 437 ? -56.363 -20.075 -1.372  1.00 29.73  ? 416 ARG C CD  1 
ATOM   9670  N  NE  . ARG C 1 437 ? -55.555 -19.208 -0.522  1.00 30.15  ? 416 ARG C NE  1 
ATOM   9671  C  CZ  . ARG C 1 437 ? -55.290 -17.938 -0.795  1.00 40.13  ? 416 ARG C CZ  1 
ATOM   9672  N  NH1 . ARG C 1 437 ? -55.666 -17.381 -1.941  1.00 30.32  ? 416 ARG C NH1 1 
ATOM   9673  N  NH2 . ARG C 1 437 ? -54.652 -17.203 0.109   1.00 32.73  ? 416 ARG C NH2 1 
ATOM   9674  N  N   . PRO C 1 438 ? -56.320 -20.323 -6.324  1.00 28.71  ? 417 PRO C N   1 
ATOM   9675  C  CA  . PRO C 1 438 ? -55.986 -19.079 -7.028  1.00 31.21  ? 417 PRO C CA  1 
ATOM   9676  C  C   . PRO C 1 438 ? -55.432 -18.077 -6.034  1.00 27.74  ? 417 PRO C C   1 
ATOM   9677  O  O   . PRO C 1 438 ? -55.907 -17.979 -4.890  1.00 28.41  ? 417 PRO C O   1 
ATOM   9678  C  CB  . PRO C 1 438 ? -57.328 -18.629 -7.609  1.00 32.90  ? 417 PRO C CB  1 
ATOM   9679  C  CG  . PRO C 1 438 ? -58.120 -19.841 -7.702  1.00 32.08  ? 417 PRO C CG  1 
ATOM   9680  C  CD  . PRO C 1 438 ? -57.714 -20.742 -6.553  1.00 26.76  ? 417 PRO C CD  1 
ATOM   9681  N  N   . LYS C 1 439 ? -54.374 -17.367 -6.451  1.00 28.36  ? 418 LYS C N   1 
ATOM   9682  C  CA  . LYS C 1 439 ? -53.608 -16.579 -5.493  1.00 29.98  ? 418 LYS C CA  1 
ATOM   9683  C  C   . LYS C 1 439 ? -54.452 -15.482 -4.874  1.00 27.14  ? 418 LYS C C   1 
ATOM   9684  O  O   . LYS C 1 439 ? -54.273 -15.145 -3.699  1.00 33.49  ? 418 LYS C O   1 
ATOM   9685  C  CB  . LYS C 1 439 ? -52.350 -16.003 -6.170  1.00 43.57  ? 418 LYS C CB  1 
ATOM   9686  C  CG  . LYS C 1 439 ? -51.346 -17.102 -6.534  1.00 53.81  ? 418 LYS C CG  1 
ATOM   9687  C  CD  . LYS C 1 439 ? -50.256 -16.679 -7.533  1.00 60.38  ? 418 LYS C CD  1 
ATOM   9688  C  CE  . LYS C 1 439 ? -49.566 -17.913 -8.172  1.00 59.62  ? 418 LYS C CE  1 
ATOM   9689  N  NZ  . LYS C 1 439 ? -50.431 -18.654 -9.198  1.00 44.56  ? 418 LYS C NZ  1 
ATOM   9690  N  N   . SER C 1 440 ? -55.394 -14.929 -5.628  1.00 30.56  ? 419 SER C N   1 
ATOM   9691  C  CA  . SER C 1 440 ? -56.207 -13.863 -5.070  1.00 27.24  ? 419 SER C CA  1 
ATOM   9692  C  C   . SER C 1 440 ? -57.314 -14.378 -4.175  1.00 27.69  ? 419 SER C C   1 
ATOM   9693  O  O   . SER C 1 440 ? -57.960 -13.566 -3.498  1.00 30.38  ? 419 SER C O   1 
ATOM   9694  C  CB  . SER C 1 440 ? -56.858 -13.034 -6.181  1.00 22.51  ? 419 SER C CB  1 
ATOM   9695  O  OG  . SER C 1 440 ? -57.913 -13.834 -6.748  1.00 26.94  ? 419 SER C OG  1 
ATOM   9696  N  N   . GLY C 1 441 ? -57.591 -15.683 -4.194  1.00 25.41  ? 420 GLY C N   1 
ATOM   9697  C  CA  . GLY C 1 441 ? -58.805 -16.200 -3.570  1.00 24.32  ? 420 GLY C CA  1 
ATOM   9698  C  C   . GLY C 1 441 ? -60.053 -16.122 -4.433  1.00 25.54  ? 420 GLY C C   1 
ATOM   9699  O  O   . GLY C 1 441 ? -61.101 -16.636 -4.016  1.00 25.45  ? 420 GLY C O   1 
ATOM   9700  N  N   . VAL C 1 442 ? -59.953 -15.530 -5.637  1.00 23.86  ? 421 VAL C N   1 
ATOM   9701  C  CA  . VAL C 1 442 ? -61.026 -15.328 -6.617  1.00 22.86  ? 421 VAL C CA  1 
ATOM   9702  C  C   . VAL C 1 442 ? -61.915 -14.162 -6.207  1.00 27.55  ? 421 VAL C C   1 
ATOM   9703  O  O   . VAL C 1 442 ? -62.775 -14.285 -5.321  1.00 24.63  ? 421 VAL C O   1 
ATOM   9704  C  CB  . VAL C 1 442 ? -61.895 -16.577 -6.865  1.00 27.14  ? 421 VAL C CB  1 
ATOM   9705  C  CG1 . VAL C 1 442 ? -62.754 -16.310 -8.090  1.00 24.69  ? 421 VAL C CG1 1 
ATOM   9706  C  CG2 . VAL C 1 442 ? -61.023 -17.850 -7.069  1.00 26.64  ? 421 VAL C CG2 1 
ATOM   9707  N  N   . ARG C 1 443 ? -61.718 -13.031 -6.860  1.00 24.62  ? 422 ARG C N   1 
ATOM   9708  C  CA  . ARG C 1 443 ? -62.430 -11.810 -6.528  1.00 25.59  ? 422 ARG C CA  1 
ATOM   9709  C  C   . ARG C 1 443 ? -63.753 -11.826 -7.259  1.00 24.42  ? 422 ARG C C   1 
ATOM   9710  O  O   . ARG C 1 443 ? -63.836 -12.313 -8.388  1.00 26.43  ? 422 ARG C O   1 
ATOM   9711  C  CB  . ARG C 1 443 ? -61.585 -10.581 -6.896  1.00 22.68  ? 422 ARG C CB  1 
ATOM   9712  C  CG  . ARG C 1 443 ? -60.388 -10.474 -5.980  1.00 23.44  ? 422 ARG C CG  1 
ATOM   9713  C  CD  . ARG C 1 443 ? -59.417 -9.369  -6.483  1.00 24.40  ? 422 ARG C CD  1 
ATOM   9714  N  NE  . ARG C 1 443 ? -58.871 -9.681  -7.797  1.00 29.86  ? 422 ARG C NE  1 
ATOM   9715  C  CZ  . ARG C 1 443 ? -58.197 -8.789  -8.513  1.00 32.06  ? 422 ARG C CZ  1 
ATOM   9716  N  NH1 . ARG C 1 443 ? -57.942 -7.577  -8.032  1.00 31.23  ? 422 ARG C NH1 1 
ATOM   9717  N  NH2 . ARG C 1 443 ? -57.795 -9.111  -9.744  1.00 25.66  ? 422 ARG C NH2 1 
ATOM   9718  N  N   . VAL C 1 444 ? -64.800 -11.349 -6.572  1.00 24.29  ? 423 VAL C N   1 
ATOM   9719  C  CA  . VAL C 1 444 ? -66.169 -11.380 -7.068  1.00 24.14  ? 423 VAL C CA  1 
ATOM   9720  C  C   . VAL C 1 444 ? -66.878 -10.109 -6.621  1.00 26.36  ? 423 VAL C C   1 
ATOM   9721  O  O   . VAL C 1 444 ? -66.528 -9.484  -5.619  1.00 31.93  ? 423 VAL C O   1 
ATOM   9722  C  CB  . VAL C 1 444 ? -66.980 -12.599 -6.552  1.00 31.44  ? 423 VAL C CB  1 
ATOM   9723  C  CG1 . VAL C 1 444 ? -66.484 -13.873 -7.176  1.00 34.06  ? 423 VAL C CG1 1 
ATOM   9724  C  CG2 . VAL C 1 444 ? -66.922 -12.672 -4.990  1.00 26.80  ? 423 VAL C CG2 1 
ATOM   9725  N  N   . THR C 1 445 ? -67.941 -9.777  -7.334  1.00 27.89  ? 424 THR C N   1 
ATOM   9726  C  CA  . THR C 1 445 ? -68.843 -8.768  -6.816  1.00 34.15  ? 424 THR C CA  1 
ATOM   9727  C  C   . THR C 1 445 ? -70.250 -9.113  -7.276  1.00 42.96  ? 424 THR C C   1 
ATOM   9728  O  O   . THR C 1 445 ? -70.436 -9.926  -8.184  1.00 34.33  ? 424 THR C O   1 
ATOM   9729  C  CB  . THR C 1 445 ? -68.427 -7.373  -7.285  1.00 40.01  ? 424 THR C CB  1 
ATOM   9730  O  OG1 . THR C 1 445 ? -69.224 -6.388  -6.604  1.00 41.72  ? 424 THR C OG1 1 
ATOM   9731  C  CG2 . THR C 1 445 ? -68.611 -7.259  -8.784  1.00 33.18  ? 424 THR C CG2 1 
ATOM   9732  N  N   . VAL C 1 446 ? -71.243 -8.494  -6.637  1.00 32.52  ? 425 VAL C N   1 
ATOM   9733  C  CA  . VAL C 1 446 ? -72.640 -8.691  -7.054  1.00 38.33  ? 425 VAL C CA  1 
ATOM   9734  C  C   . VAL C 1 446 ? -73.252 -7.374  -7.549  1.00 43.14  ? 425 VAL C C   1 
ATOM   9735  O  O   . VAL C 1 446 ? -73.004 -6.322  -6.954  1.00 34.43  ? 425 VAL C O   1 
ATOM   9736  C  CB  . VAL C 1 446 ? -73.498 -9.274  -5.910  1.00 43.39  ? 425 VAL C CB  1 
ATOM   9737  C  CG1 . VAL C 1 446 ? -74.984 -9.038  -6.193  1.00 38.35  ? 425 VAL C CG1 1 
ATOM   9738  C  CG2 . VAL C 1 446 ? -73.210 -10.771 -5.722  1.00 36.92  ? 425 VAL C CG2 1 
HETATM 9739  C  CHA . HEM D 2 .   ? -23.750 -20.331 19.014  1.00 19.34  ? 501 HEM A CHA 1 
HETATM 9740  C  CHB . HEM D 2 .   ? -19.209 -21.570 20.193  1.00 18.79  ? 501 HEM A CHB 1 
HETATM 9741  C  CHC . HEM D 2 .   ? -18.516 -23.306 15.720  1.00 19.47  ? 501 HEM A CHC 1 
HETATM 9742  C  CHD . HEM D 2 .   ? -22.820 -21.609 14.414  1.00 20.84  ? 501 HEM A CHD 1 
HETATM 9743  C  C1A . HEM D 2 .   ? -22.618 -20.590 19.733  1.00 20.87  ? 501 HEM A C1A 1 
HETATM 9744  C  C2A . HEM D 2 .   ? -22.443 -20.305 21.141  1.00 21.89  ? 501 HEM A C2A 1 
HETATM 9745  C  C3A . HEM D 2 .   ? -21.197 -20.640 21.451  1.00 26.35  ? 501 HEM A C3A 1 
HETATM 9746  C  C4A . HEM D 2 .   ? -20.534 -21.156 20.285  1.00 20.03  ? 501 HEM A C4A 1 
HETATM 9747  C  CMA . HEM D 2 .   ? -20.549 -20.512 22.846  1.00 22.37  ? 501 HEM A CMA 1 
HETATM 9748  C  CAA . HEM D 2 .   ? -23.511 -19.684 22.098  1.00 20.29  ? 501 HEM A CAA 1 
HETATM 9749  C  CBA . HEM D 2 .   ? -24.367 -20.785 22.763  1.00 19.38  ? 501 HEM A CBA 1 
HETATM 9750  C  CGA . HEM D 2 .   ? -25.484 -20.108 23.557  1.00 21.79  ? 501 HEM A CGA 1 
HETATM 9751  O  O1A . HEM D 2 .   ? -25.932 -20.675 24.562  1.00 23.04  ? 501 HEM A O1A 1 
HETATM 9752  O  O2A . HEM D 2 .   ? -25.937 -18.996 23.181  1.00 20.41  ? 501 HEM A O2A 1 
HETATM 9753  C  C1B . HEM D 2 .   ? -18.605 -22.084 19.047  1.00 16.21  ? 501 HEM A C1B 1 
HETATM 9754  C  C2B . HEM D 2 .   ? -17.204 -22.446 18.907  1.00 17.99  ? 501 HEM A C2B 1 
HETATM 9755  C  C3B . HEM D 2 .   ? -17.010 -22.917 17.680  1.00 23.37  ? 501 HEM A C3B 1 
HETATM 9756  C  C4B . HEM D 2 .   ? -18.279 -22.846 16.985  1.00 20.52  ? 501 HEM A C4B 1 
HETATM 9757  C  CMB . HEM D 2 .   ? -16.184 -22.280 20.069  1.00 21.19  ? 501 HEM A CMB 1 
HETATM 9758  C  CAB . HEM D 2 .   ? -15.752 -23.438 16.971  1.00 23.14  ? 501 HEM A CAB 1 
HETATM 9759  C  CBB . HEM D 2 .   ? -14.556 -22.911 17.096  1.00 39.67  ? 501 HEM A CBB 1 
HETATM 9760  C  C1C . HEM D 2 .   ? -19.665 -23.115 15.004  1.00 18.43  ? 501 HEM A C1C 1 
HETATM 9761  C  C2C . HEM D 2 .   ? -19.925 -23.590 13.670  1.00 23.29  ? 501 HEM A C2C 1 
HETATM 9762  C  C3C . HEM D 2 .   ? -21.120 -23.098 13.305  1.00 19.62  ? 501 HEM A C3C 1 
HETATM 9763  C  C4C . HEM D 2 .   ? -21.623 -22.294 14.399  1.00 21.44  ? 501 HEM A C4C 1 
HETATM 9764  C  CMC . HEM D 2 .   ? -18.947 -24.511 12.885  1.00 20.12  ? 501 HEM A CMC 1 
HETATM 9765  C  CAC . HEM D 2 .   ? -21.906 -23.285 11.988  1.00 20.69  ? 501 HEM A CAC 1 
HETATM 9766  C  CBC . HEM D 2 .   ? -21.416 -23.832 10.865  1.00 24.69  ? 501 HEM A CBC 1 
HETATM 9767  C  C1D . HEM D 2 .   ? -23.424 -21.058 15.525  1.00 19.42  ? 501 HEM A C1D 1 
HETATM 9768  C  C2D . HEM D 2 .   ? -24.683 -20.344 15.527  1.00 17.88  ? 501 HEM A C2D 1 
HETATM 9769  C  C3D . HEM D 2 .   ? -24.942 -19.990 16.809  1.00 17.60  ? 501 HEM A C3D 1 
HETATM 9770  C  C4D . HEM D 2 .   ? -23.846 -20.459 17.647  1.00 18.38  ? 501 HEM A C4D 1 
HETATM 9771  C  CMD . HEM D 2 .   ? -25.570 -20.072 14.272  1.00 18.04  ? 501 HEM A CMD 1 
HETATM 9772  C  CAD . HEM D 2 .   ? -26.146 -19.202 17.383  1.00 16.35  ? 501 HEM A CAD 1 
HETATM 9773  C  CBD . HEM D 2 .   ? -27.194 -20.193 17.895  1.00 17.41  ? 501 HEM A CBD 1 
HETATM 9774  C  CGD . HEM D 2 .   ? -28.333 -19.493 18.637  1.00 20.11  ? 501 HEM A CGD 1 
HETATM 9775  O  O1D . HEM D 2 .   ? -28.155 -18.408 19.251  1.00 19.80  ? 501 HEM A O1D 1 
HETATM 9776  O  O2D . HEM D 2 .   ? -29.445 -20.050 18.635  1.00 20.71  ? 501 HEM A O2D 1 
HETATM 9777  N  NA  . HEM D 2 .   ? -21.426 -21.112 19.226  1.00 18.40  ? 501 HEM A NA  1 
HETATM 9778  N  NB  . HEM D 2 .   ? -19.209 -22.324 17.846  1.00 20.26  ? 501 HEM A NB  1 
HETATM 9779  N  NC  . HEM D 2 .   ? -20.725 -22.332 15.417  1.00 20.95  ? 501 HEM A NC  1 
HETATM 9780  N  ND  . HEM D 2 .   ? -22.950 -21.071 16.835  1.00 18.90  ? 501 HEM A ND  1 
HETATM 9781  FE FE  . HEM D 2 .   ? -21.180 -21.934 17.402  1.00 20.43  ? 501 HEM A FE  1 
HETATM 9782  C  C1  . OLA E 3 .   ? -17.910 -17.720 16.045  1.00 25.71  ? 502 OLA A C1  1 
HETATM 9783  O  O1  . OLA E 3 .   ? -17.091 -17.308 15.188  1.00 28.51  ? 502 OLA A O1  1 
HETATM 9784  O  O2  . OLA E 3 .   ? -18.979 -17.078 16.181  1.00 29.59  ? 502 OLA A O2  1 
HETATM 9785  C  C2  . OLA E 3 .   ? -17.626 -18.983 16.875  1.00 28.80  ? 502 OLA A C2  1 
HETATM 9786  C  C3  . OLA E 3 .   ? -16.440 -18.690 17.775  1.00 35.83  ? 502 OLA A C3  1 
HETATM 9787  C  C4  . OLA E 3 .   ? -16.803 -17.647 18.829  1.00 38.99  ? 502 OLA A C4  1 
HETATM 9788  C  C5  . OLA E 3 .   ? -17.404 -18.208 20.116  1.00 47.18  ? 502 OLA A C5  1 
HETATM 9789  C  C6  . OLA E 3 .   ? -17.922 -17.114 21.068  1.00 42.11  ? 502 OLA A C6  1 
HETATM 9790  C  C7  . OLA E 3 .   ? -16.799 -16.456 21.868  1.00 32.20  ? 502 OLA A C7  1 
HETATM 9791  C  C8  . OLA E 3 .   ? -17.365 -15.409 22.817  1.00 33.30  ? 502 OLA A C8  1 
HETATM 9792  C  C9  . OLA E 3 .   ? -16.218 -14.543 23.272  1.00 42.09  ? 502 OLA A C9  1 
HETATM 9793  C  C10 . OLA E 3 .   ? -16.343 -13.708 24.466  1.00 34.35  ? 502 OLA A C10 1 
HETATM 9794  C  C11 . OLA E 3 .   ? -17.648 -13.676 25.227  1.00 36.15  ? 502 OLA A C11 1 
HETATM 9795  C  C12 . OLA E 3 .   ? -17.560 -12.615 26.298  1.00 37.08  ? 502 OLA A C12 1 
HETATM 9796  C  C13 . OLA E 3 .   ? -18.829 -12.634 27.140  1.00 35.47  ? 502 OLA A C13 1 
HETATM 9797  C  C14 . OLA E 3 .   ? -18.965 -11.381 27.973  1.00 44.53  ? 502 OLA A C14 1 
HETATM 9798  C  C15 . OLA E 3 .   ? -20.133 -11.563 28.920  1.00 38.85  ? 502 OLA A C15 1 
HETATM 9799  C  C16 . OLA E 3 .   ? -20.143 -10.427 29.925  1.00 37.55  ? 502 OLA A C16 1 
HETATM 9800  C  C17 . OLA E 3 .   ? -21.184 -9.367  29.605  1.00 46.69  ? 502 OLA A C17 1 
HETATM 9801  C  C18 . OLA E 3 .   ? -21.130 -8.277  30.673  1.00 58.28  ? 502 OLA A C18 1 
HETATM 9802  C  C1  . PEG F 4 .   ? -12.671 -3.733  24.135  1.00 56.86  ? 503 PEG A C1  1 
HETATM 9803  O  O1  . PEG F 4 .   ? -13.038 -2.661  24.994  1.00 66.45  ? 503 PEG A O1  1 
HETATM 9804  C  C2  . PEG F 4 .   ? -13.793 -4.707  23.955  1.00 53.90  ? 503 PEG A C2  1 
HETATM 9805  O  O2  . PEG F 4 .   ? -14.045 -5.381  25.184  1.00 65.30  ? 503 PEG A O2  1 
HETATM 9806  C  C3  . PEG F 4 .   ? -15.092 -4.798  25.953  1.00 60.98  ? 503 PEG A C3  1 
HETATM 9807  C  C4  . PEG F 4 .   ? -15.626 -5.812  26.921  1.00 64.72  ? 503 PEG A C4  1 
HETATM 9808  O  O4  . PEG F 4 .   ? -16.382 -5.213  27.960  1.00 59.43  ? 503 PEG A O4  1 
HETATM 9809  C  C1  . GOL G 5 .   ? -34.390 -15.616 -7.313  1.00 51.81  ? 504 GOL A C1  1 
HETATM 9810  O  O1  . GOL G 5 .   ? -35.392 -15.766 -8.301  1.00 61.42  ? 504 GOL A O1  1 
HETATM 9811  C  C2  . GOL G 5 .   ? -34.457 -16.844 -6.330  1.00 58.17  ? 504 GOL A C2  1 
HETATM 9812  O  O2  . GOL G 5 .   ? -33.280 -17.571 -6.312  1.00 74.73  ? 504 GOL A O2  1 
HETATM 9813  C  C3  . GOL G 5 .   ? -34.731 -16.267 -4.926  1.00 65.53  ? 504 GOL A C3  1 
HETATM 9814  O  O3  . GOL G 5 .   ? -33.891 -16.985 -4.053  1.00 58.50  ? 504 GOL A O3  1 
HETATM 9815  C  C1  . GOL H 5 .   ? -4.460  -11.897 20.202  1.00 65.98  ? 505 GOL A C1  1 
HETATM 9816  O  O1  . GOL H 5 .   ? -5.597  -11.051 20.010  1.00 43.04  ? 505 GOL A O1  1 
HETATM 9817  C  C2  . GOL H 5 .   ? -3.374  -11.565 19.135  1.00 66.99  ? 505 GOL A C2  1 
HETATM 9818  O  O2  . GOL H 5 .   ? -3.559  -12.297 17.991  1.00 59.21  ? 505 GOL A O2  1 
HETATM 9819  C  C3  . GOL H 5 .   ? -3.493  -10.032 18.850  1.00 68.68  ? 505 GOL A C3  1 
HETATM 9820  O  O3  . GOL H 5 .   ? -2.692  -9.774  17.744  1.00 51.73  ? 505 GOL A O3  1 
HETATM 9821  C  C1  . GOL I 5 .   ? -9.528  1.196   9.054   1.00 67.49  ? 506 GOL A C1  1 
HETATM 9822  O  O1  . GOL I 5 .   ? -8.981  0.941   10.320  1.00 70.28  ? 506 GOL A O1  1 
HETATM 9823  C  C2  . GOL I 5 .   ? -8.417  0.836   8.041   1.00 66.57  ? 506 GOL A C2  1 
HETATM 9824  O  O2  . GOL I 5 .   ? -7.409  1.796   8.040   1.00 86.64  ? 506 GOL A O2  1 
HETATM 9825  C  C3  . GOL I 5 .   ? -7.901  -0.567  8.517   1.00 71.51  ? 506 GOL A C3  1 
HETATM 9826  O  O3  . GOL I 5 .   ? -7.039  -1.060  7.532   1.00 74.61  ? 506 GOL A O3  1 
HETATM 9827  CL CL  . CL  J 6 .   ? -14.722 -37.503 33.761  1.00 38.24  ? 507 CL  A CL  1 
HETATM 9828  C  C1  . PGE K 7 .   ? -15.859 0.118   11.170  1.00 40.04  ? 508 PGE A C1  1 
HETATM 9829  O  O1  . PGE K 7 .   ? -14.863 0.867   10.499  1.00 56.10  ? 508 PGE A O1  1 
HETATM 9830  C  C2  . PGE K 7 .   ? -17.238 0.688   10.875  1.00 52.64  ? 508 PGE A C2  1 
HETATM 9831  O  O2  . PGE K 7 .   ? -18.197 0.083   11.733  1.00 53.82  ? 508 PGE A O2  1 
HETATM 9832  C  C3  . PGE K 7 .   ? -17.944 -1.287  11.982  1.00 51.91  ? 508 PGE A C3  1 
HETATM 9833  C  C4  . PGE K 7 .   ? -19.026 -2.202  11.449  1.00 44.99  ? 508 PGE A C4  1 
HETATM 9834  O  O4  . PGE K 7 .   ? -21.973 -4.883  13.162  1.00 31.54  ? 508 PGE A O4  1 
HETATM 9835  C  C6  . PGE K 7 .   ? -21.307 -3.667  13.451  1.00 50.69  ? 508 PGE A C6  1 
HETATM 9836  C  C5  . PGE K 7 .   ? -21.095 -2.992  12.118  1.00 48.52  ? 508 PGE A C5  1 
HETATM 9837  O  O3  . PGE K 7 .   ? -20.173 -1.952  12.233  1.00 70.97  ? 508 PGE A O3  1 
HETATM 9838  C  CHA . HEM L 2 .   ? -43.217 9.272   34.087  1.00 20.89  ? 501 HEM B CHA 1 
HETATM 9839  C  CHB . HEM L 2 .   ? -45.370 12.728  31.474  1.00 23.78  ? 501 HEM B CHB 1 
HETATM 9840  C  CHC . HEM L 2 .   ? -44.467 15.931  35.005  1.00 21.82  ? 501 HEM B CHC 1 
HETATM 9841  C  CHD . HEM L 2 .   ? -41.928 12.605  37.401  1.00 21.18  ? 501 HEM B CHD 1 
HETATM 9842  C  C1A . HEM L 2 .   ? -43.919 9.900   33.109  1.00 22.51  ? 501 HEM B C1A 1 
HETATM 9843  C  C2A . HEM L 2 .   ? -44.418 9.276   31.899  1.00 21.97  ? 501 HEM B C2A 1 
HETATM 9844  C  C3A . HEM L 2 .   ? -45.006 10.243  31.163  1.00 23.00  ? 501 HEM B C3A 1 
HETATM 9845  C  C4A . HEM L 2 .   ? -44.903 11.505  31.901  1.00 22.79  ? 501 HEM B C4A 1 
HETATM 9846  C  CMA . HEM L 2 .   ? -45.693 10.075  29.797  1.00 21.81  ? 501 HEM B CMA 1 
HETATM 9847  C  CAA . HEM L 2 .   ? -44.246 7.770   31.558  1.00 22.53  ? 501 HEM B CAA 1 
HETATM 9848  C  CBA . HEM L 2 .   ? -45.499 6.965   31.957  1.00 21.46  ? 501 HEM B CBA 1 
HETATM 9849  C  CGA . HEM L 2 .   ? -45.240 5.487   31.691  1.00 19.78  ? 501 HEM B CGA 1 
HETATM 9850  O  O1A . HEM L 2 .   ? -46.233 4.711   31.532  1.00 21.69  ? 501 HEM B O1A 1 
HETATM 9851  O  O2A . HEM L 2 .   ? -44.031 5.094   31.625  1.00 23.65  ? 501 HEM B O2A 1 
HETATM 9852  C  C1B . HEM L 2 .   ? -45.237 13.920  32.155  1.00 22.43  ? 501 HEM B C1B 1 
HETATM 9853  C  C2B . HEM L 2 .   ? -45.602 15.244  31.681  1.00 23.51  ? 501 HEM B C2B 1 
HETATM 9854  C  C3B . HEM L 2 .   ? -45.339 16.127  32.660  1.00 19.47  ? 501 HEM B C3B 1 
HETATM 9855  C  C4B . HEM L 2 .   ? -44.799 15.384  33.779  1.00 22.53  ? 501 HEM B C4B 1 
HETATM 9856  C  CMB . HEM L 2 .   ? -46.165 15.498  30.274  1.00 22.39  ? 501 HEM B CMB 1 
HETATM 9857  C  CAB . HEM L 2 .   ? -45.509 17.666  32.733  1.00 23.17  ? 501 HEM B CAB 1 
HETATM 9858  C  CBB . HEM L 2 .   ? -45.969 18.452  31.774  1.00 29.82  ? 501 HEM B CBB 1 
HETATM 9859  C  C1C . HEM L 2 .   ? -43.826 15.289  36.027  1.00 25.78  ? 501 HEM B C1C 1 
HETATM 9860  C  C2C . HEM L 2 .   ? -43.509 15.843  37.316  1.00 25.64  ? 501 HEM B C2C 1 
HETATM 9861  C  C3C . HEM L 2 .   ? -42.794 14.920  37.986  1.00 23.12  ? 501 HEM B C3C 1 
HETATM 9862  C  C4C . HEM L 2 .   ? -42.637 13.758  37.119  1.00 23.37  ? 501 HEM B C4C 1 
HETATM 9863  C  CMC . HEM L 2 .   ? -43.970 17.255  37.790  1.00 21.60  ? 501 HEM B CMC 1 
HETATM 9864  C  CAC . HEM L 2 .   ? -42.221 14.974  39.412  1.00 25.50  ? 501 HEM B CAC 1 
HETATM 9865  C  CBC . HEM L 2 .   ? -42.054 16.107  40.137  1.00 26.51  ? 501 HEM B CBC 1 
HETATM 9866  C  C1D . HEM L 2 .   ? -41.970 11.432  36.673  1.00 23.93  ? 501 HEM B C1D 1 
HETATM 9867  C  C2D . HEM L 2 .   ? -41.274 10.193  36.972  1.00 21.29  ? 501 HEM B C2D 1 
HETATM 9868  C  C3D . HEM L 2 .   ? -41.615 9.282   36.050  1.00 22.38  ? 501 HEM B C3D 1 
HETATM 9869  C  C4D . HEM L 2 .   ? -42.575 9.907   35.145  1.00 23.16  ? 501 HEM B C4D 1 
HETATM 9870  C  CMD . HEM L 2 .   ? -40.269 10.024  38.118  1.00 23.24  ? 501 HEM B CMD 1 
HETATM 9871  C  CAD . HEM L 2 .   ? -41.139 7.808   35.946  1.00 19.35  ? 501 HEM B CAD 1 
HETATM 9872  C  CBD . HEM L 2 .   ? -42.191 6.911   36.620  1.00 24.15  ? 501 HEM B CBD 1 
HETATM 9873  C  CGD . HEM L 2 .   ? -41.863 5.426   36.417  1.00 22.74  ? 501 HEM B CGD 1 
HETATM 9874  O  O1D . HEM L 2 .   ? -41.256 5.100   35.374  1.00 23.67  ? 501 HEM B O1D 1 
HETATM 9875  O  O2D . HEM L 2 .   ? -42.236 4.552   37.261  1.00 22.79  ? 501 HEM B O2D 1 
HETATM 9876  N  NA  . HEM L 2 .   ? -44.228 11.263  33.078  1.00 21.31  ? 501 HEM B NA  1 
HETATM 9877  N  NB  . HEM L 2 .   ? -44.736 14.047  33.427  1.00 22.52  ? 501 HEM B NB  1 
HETATM 9878  N  NC  . HEM L 2 .   ? -43.283 14.023  35.944  1.00 22.69  ? 501 HEM B NC  1 
HETATM 9879  N  ND  . HEM L 2 .   ? -42.742 11.210  35.551  1.00 20.74  ? 501 HEM B ND  1 
HETATM 9880  FE FE  . HEM L 2 .   ? -43.971 12.596  34.620  1.00 22.32  ? 501 HEM B FE  1 
HETATM 9881  C  C1  . OLA M 3 .   ? -40.034 15.001  31.759  1.00 34.16  ? 502 OLA B C1  1 
HETATM 9882  O  O1  . OLA M 3 .   ? -39.267 15.969  31.722  1.00 29.15  ? 502 OLA B O1  1 
HETATM 9883  O  O2  . OLA M 3 .   ? -39.536 13.863  31.951  1.00 30.13  ? 502 OLA B O2  1 
HETATM 9884  C  C2  . OLA M 3 .   ? -41.537 15.226  31.591  1.00 27.96  ? 502 OLA B C2  1 
HETATM 9885  C  C3  . OLA M 3 .   ? -41.728 15.813  30.195  1.00 34.48  ? 502 OLA B C3  1 
HETATM 9886  C  C4  . OLA M 3 .   ? -41.398 14.760  29.124  1.00 45.07  ? 502 OLA B C4  1 
HETATM 9887  C  C5  . OLA M 3 .   ? -42.578 13.822  28.878  1.00 39.30  ? 502 OLA B C5  1 
HETATM 9888  C  C6  . OLA M 3 .   ? -42.188 12.593  28.060  1.00 41.72  ? 502 OLA B C6  1 
HETATM 9889  C  C7  . OLA M 3 .   ? -42.140 12.974  26.584  1.00 34.04  ? 502 OLA B C7  1 
HETATM 9890  C  C8  . OLA M 3 .   ? -41.862 11.767  25.692  1.00 33.85  ? 502 OLA B C8  1 
HETATM 9891  C  C9  . OLA M 3 .   ? -41.288 12.278  24.398  1.00 39.03  ? 502 OLA B C9  1 
HETATM 9892  C  C10 . OLA M 3 .   ? -41.245 11.428  23.187  1.00 39.44  ? 502 OLA B C10 1 
HETATM 9893  C  C11 . OLA M 3 .   ? -41.416 9.934   23.291  1.00 38.97  ? 502 OLA B C11 1 
HETATM 9894  C  C12 . OLA M 3 .   ? -41.122 9.287   21.945  1.00 44.95  ? 502 OLA B C12 1 
HETATM 9895  C  C13 . OLA M 3 .   ? -41.659 7.864   21.910  1.00 36.71  ? 502 OLA B C13 1 
HETATM 9896  C  C14 . OLA M 3 .   ? -40.700 6.976   21.148  1.00 38.92  ? 502 OLA B C14 1 
HETATM 9897  C  C15 . OLA M 3 .   ? -41.352 5.640   20.844  1.00 44.76  ? 502 OLA B C15 1 
HETATM 9898  C  C16 . OLA M 3 .   ? -40.800 5.110   19.524  1.00 45.20  ? 502 OLA B C16 1 
HETATM 9899  C  C17 . OLA M 3 .   ? -40.006 3.829   19.716  1.00 49.40  ? 502 OLA B C17 1 
HETATM 9900  C  C18 . OLA M 3 .   ? -39.646 3.189   18.372  1.00 50.66  ? 502 OLA B C18 1 
HETATM 9901  C  C1  . PEG N 4 .   ? -26.354 35.968  42.206  1.00 69.51  ? 503 PEG B C1  1 
HETATM 9902  O  O1  . PEG N 4 .   ? -27.712 35.607  42.474  1.00 47.96  ? 503 PEG B O1  1 
HETATM 9903  C  C2  . PEG N 4 .   ? -25.429 34.785  42.293  1.00 67.29  ? 503 PEG B C2  1 
HETATM 9904  O  O2  . PEG N 4 .   ? -24.214 35.043  41.578  1.00 61.87  ? 503 PEG B O2  1 
HETATM 9905  C  C3  . PEG N 4 .   ? -23.716 33.923  40.842  1.00 38.37  ? 503 PEG B C3  1 
HETATM 9906  C  C4  . PEG N 4 .   ? -24.196 32.615  41.403  1.00 26.33  ? 503 PEG B C4  1 
HETATM 9907  O  O4  . PEG N 4 .   ? -23.167 31.961  42.115  1.00 37.19  ? 503 PEG B O4  1 
HETATM 9908  C  C1  . GOL O 5 .   ? -68.353 12.149  39.710  1.00 63.45  ? 504 GOL B C1  1 
HETATM 9909  O  O1  . GOL O 5 .   ? -68.413 11.861  38.343  1.00 60.48  ? 504 GOL B O1  1 
HETATM 9910  C  C2  . GOL O 5 .   ? -66.991 11.627  40.198  1.00 62.27  ? 504 GOL B C2  1 
HETATM 9911  O  O2  . GOL O 5 .   ? -65.996 12.578  40.046  1.00 64.11  ? 504 GOL B O2  1 
HETATM 9912  C  C3  . GOL O 5 .   ? -67.188 11.221  41.686  1.00 77.13  ? 504 GOL B C3  1 
HETATM 9913  O  O3  . GOL O 5 .   ? -66.153 10.325  41.990  1.00 70.53  ? 504 GOL B O3  1 
HETATM 9914  C  C1  . GOL P 5 .   ? -36.169 26.114  19.710  1.00 63.38  ? 505 GOL B C1  1 
HETATM 9915  O  O1  . GOL P 5 .   ? -34.880 25.816  20.218  1.00 63.41  ? 505 GOL B O1  1 
HETATM 9916  C  C2  . GOL P 5 .   ? -36.608 24.934  18.783  1.00 69.36  ? 505 GOL B C2  1 
HETATM 9917  O  O2  . GOL P 5 .   ? -35.774 24.795  17.670  1.00 68.21  ? 505 GOL B O2  1 
HETATM 9918  C  C3  . GOL P 5 .   ? -38.087 25.233  18.383  1.00 56.87  ? 505 GOL B C3  1 
HETATM 9919  O  O3  . GOL P 5 .   ? -38.894 24.550  19.292  1.00 61.60  ? 505 GOL B O3  1 
HETATM 9920  C  C1  . PGE Q 7 .   ? -31.376 11.772  14.729  1.00 51.37  ? 506 PGE B C1  1 
HETATM 9921  O  O1  . PGE Q 7 .   ? -31.045 10.697  13.862  1.00 60.22  ? 506 PGE B O1  1 
HETATM 9922  C  C2  . PGE Q 7 .   ? -32.370 11.231  15.733  1.00 40.89  ? 506 PGE B C2  1 
HETATM 9923  O  O2  . PGE Q 7 .   ? -32.991 12.314  16.402  1.00 58.63  ? 506 PGE B O2  1 
HETATM 9924  C  C3  . PGE Q 7 .   ? -33.798 11.983  17.525  1.00 44.46  ? 506 PGE B C3  1 
HETATM 9925  C  C4  . PGE Q 7 .   ? -35.062 11.285  17.075  1.00 47.24  ? 506 PGE B C4  1 
HETATM 9926  O  O4  . PGE Q 7 .   ? -34.540 7.691   16.171  1.00 65.44  ? 506 PGE B O4  1 
HETATM 9927  C  C6  . PGE Q 7 .   ? -35.903 7.819   16.564  1.00 50.04  ? 506 PGE B C6  1 
HETATM 9928  C  C5  . PGE Q 7 .   ? -36.031 9.146   17.272  1.00 63.54  ? 506 PGE B C5  1 
HETATM 9929  O  O3  . PGE Q 7 .   ? -34.842 9.887   17.057  1.00 60.49  ? 506 PGE B O3  1 
HETATM 9930  C  CHA . HEM R 2 .   ? -59.813 -37.755 7.021   1.00 25.64  ? 501 HEM C CHA 1 
HETATM 9931  C  CHB . HEM R 2 .   ? -59.859 -34.841 3.126   1.00 22.63  ? 501 HEM C CHB 1 
HETATM 9932  C  CHC . HEM R 2 .   ? -63.643 -32.423 4.933   1.00 21.79  ? 501 HEM C CHC 1 
HETATM 9933  C  CHD . HEM R 2 .   ? -63.307 -35.020 8.986   1.00 23.51  ? 501 HEM C CHD 1 
HETATM 9934  C  C1A . HEM R 2 .   ? -59.554 -37.200 5.781   1.00 26.20  ? 501 HEM C C1A 1 
HETATM 9935  C  C2A . HEM R 2 .   ? -58.546 -37.687 4.868   1.00 25.77  ? 501 HEM C C2A 1 
HETATM 9936  C  C3A . HEM R 2 .   ? -58.549 -36.892 3.802   1.00 23.59  ? 501 HEM C C3A 1 
HETATM 9937  C  C4A . HEM R 2 .   ? -59.555 -35.875 4.003   1.00 22.32  ? 501 HEM C C4A 1 
HETATM 9938  C  CMA . HEM R 2 .   ? -57.646 -36.994 2.556   1.00 24.11  ? 501 HEM C CMA 1 
HETATM 9939  C  CAA . HEM R 2 .   ? -57.630 -38.909 5.134   1.00 23.65  ? 501 HEM C CAA 1 
HETATM 9940  C  CBA . HEM R 2 .   ? -58.155 -40.219 4.527   1.00 22.69  ? 501 HEM C CBA 1 
HETATM 9941  C  CGA . HEM R 2 .   ? -57.234 -41.363 4.897   1.00 25.05  ? 501 HEM C CGA 1 
HETATM 9942  O  O1A . HEM R 2 .   ? -57.157 -42.333 4.092   1.00 25.95  ? 501 HEM C O1A 1 
HETATM 9943  O  O2A . HEM R 2 .   ? -56.573 -41.319 5.964   1.00 27.26  ? 501 HEM C O2A 1 
HETATM 9944  C  C1B . HEM R 2 .   ? -60.822 -33.869 3.321   1.00 21.01  ? 501 HEM C C1B 1 
HETATM 9945  C  C2B . HEM R 2 .   ? -61.061 -32.709 2.495   1.00 22.83  ? 501 HEM C C2B 1 
HETATM 9946  C  C3B . HEM R 2 .   ? -62.103 -32.030 3.005   1.00 20.63  ? 501 HEM C C3B 1 
HETATM 9947  C  C4B . HEM R 2 .   ? -62.558 -32.750 4.166   1.00 24.52  ? 501 HEM C C4B 1 
HETATM 9948  C  CMB . HEM R 2 .   ? -60.177 -32.381 1.277   1.00 24.51  ? 501 HEM C CMB 1 
HETATM 9949  C  CAB . HEM R 2 .   ? -62.774 -30.711 2.551   1.00 27.17  ? 501 HEM C CAB 1 
HETATM 9950  C  CBB . HEM R 2 .   ? -62.441 -30.052 1.452   1.00 34.02  ? 501 HEM C CBB 1 
HETATM 9951  C  C1C . HEM R 2 .   ? -63.978 -32.989 6.127   1.00 25.86  ? 501 HEM C C1C 1 
HETATM 9952  C  C2C . HEM R 2 .   ? -65.132 -32.647 6.949   1.00 24.58  ? 501 HEM C C2C 1 
HETATM 9953  C  C3C . HEM R 2 .   ? -65.017 -33.380 8.076   1.00 25.90  ? 501 HEM C C3C 1 
HETATM 9954  C  C4C . HEM R 2 .   ? -63.794 -34.167 8.004   1.00 22.19  ? 501 HEM C C4C 1 
HETATM 9955  C  CMC . HEM R 2 .   ? -66.271 -31.667 6.508   1.00 23.62  ? 501 HEM C CMC 1 
HETATM 9956  C  CAC . HEM R 2 .   ? -65.968 -33.445 9.292   1.00 25.48  ? 501 HEM C CAC 1 
HETATM 9957  C  CBC . HEM R 2 .   ? -66.952 -32.550 9.497   1.00 29.62  ? 501 HEM C CBC 1 
HETATM 9958  C  C1D . HEM R 2 .   ? -62.271 -35.933 8.865   1.00 23.30  ? 501 HEM C C1D 1 
HETATM 9959  C  C2D . HEM R 2 .   ? -61.755 -36.812 9.890   1.00 23.48  ? 501 HEM C C2D 1 
HETATM 9960  C  C3D . HEM R 2 .   ? -60.788 -37.586 9.358   1.00 25.89  ? 501 HEM C C3D 1 
HETATM 9961  C  C4D . HEM R 2 .   ? -60.651 -37.196 7.974   1.00 25.74  ? 501 HEM C C4D 1 
HETATM 9962  C  CMD . HEM R 2 .   ? -62.277 -36.818 11.339  1.00 22.47  ? 501 HEM C CMD 1 
HETATM 9963  C  CAD . HEM R 2 .   ? -59.915 -38.685 10.032  1.00 24.69  ? 501 HEM C CAD 1 
HETATM 9964  C  CBD . HEM R 2 .   ? -60.558 -40.043 9.763   1.00 25.53  ? 501 HEM C CBD 1 
HETATM 9965  C  CGD . HEM R 2 .   ? -59.686 -41.211 10.163  1.00 24.32  ? 501 HEM C CGD 1 
HETATM 9966  O  O1D . HEM R 2 .   ? -58.424 -41.069 10.197  1.00 29.26  ? 501 HEM C O1D 1 
HETATM 9967  O  O2D . HEM R 2 .   ? -60.252 -42.317 10.386  1.00 25.98  ? 501 HEM C O2D 1 
HETATM 9968  N  NA  . HEM R 2 .   ? -60.158 -36.095 5.219   1.00 27.06  ? 501 HEM C NA  1 
HETATM 9969  N  NB  . HEM R 2 .   ? -61.767 -33.861 4.318   1.00 24.81  ? 501 HEM C NB  1 
HETATM 9970  N  NC  . HEM R 2 .   ? -63.178 -33.904 6.792   1.00 25.28  ? 501 HEM C NC  1 
HETATM 9971  N  ND  . HEM R 2 .   ? -61.557 -36.201 7.716   1.00 21.90  ? 501 HEM C ND  1 
HETATM 9972  FE FE  . HEM R 2 .   ? -61.865 -35.145 5.936   1.00 24.50  ? 501 HEM C FE  1 
HETATM 9973  C  C1  . OLA S 3 .   ? -58.761 -30.891 7.096   1.00 34.87  ? 502 OLA C C1  1 
HETATM 9974  O  O1  . OLA S 3 .   ? -58.778 -29.713 7.529   1.00 28.78  ? 502 OLA C O1  1 
HETATM 9975  O  O2  . OLA S 3 .   ? -58.283 -31.764 7.839   1.00 33.29  ? 502 OLA C O2  1 
HETATM 9976  C  C2  . OLA S 3 .   ? -59.311 -31.250 5.716   1.00 25.63  ? 502 OLA C C2  1 
HETATM 9977  C  C3  . OLA S 3 .   ? -58.438 -30.497 4.725   1.00 32.65  ? 502 OLA C C3  1 
HETATM 9978  C  C4  . OLA S 3 .   ? -57.037 -31.121 4.772   1.00 40.53  ? 502 OLA C C4  1 
HETATM 9979  C  C5  . OLA S 3 .   ? -56.810 -32.146 3.666   1.00 32.89  ? 502 OLA C C5  1 
HETATM 9980  C  C6  . OLA S 3 .   ? -55.567 -32.996 3.923   1.00 33.54  ? 502 OLA C C6  1 
HETATM 9981  C  C7  . OLA S 3 .   ? -54.407 -32.332 3.214   1.00 32.98  ? 502 OLA C C7  1 
HETATM 9982  C  C8  . OLA S 3 .   ? -53.162 -33.194 3.300   1.00 36.46  ? 502 OLA C C8  1 
HETATM 9983  C  C9  . OLA S 3 .   ? -52.081 -32.311 2.768   1.00 37.07  ? 502 OLA C C9  1 
HETATM 9984  C  C10 . OLA S 3 .   ? -50.723 -32.821 2.598   1.00 34.10  ? 502 OLA C C10 1 
HETATM 9985  C  C11 . OLA S 3 .   ? -50.310 -34.135 3.182   1.00 41.18  ? 502 OLA C C11 1 
HETATM 9986  C  C12 . OLA S 3 .   ? -48.976 -34.448 2.527   1.00 42.48  ? 502 OLA C C12 1 
HETATM 9987  C  C13 . OLA S 3 .   ? -48.385 -35.775 2.986   1.00 37.38  ? 502 OLA C C13 1 
HETATM 9988  C  C14 . OLA S 3 .   ? -47.023 -35.910 2.326   1.00 42.45  ? 502 OLA C C14 1 
HETATM 9989  C  C15 . OLA S 3 .   ? -46.514 -37.339 2.332   1.00 47.25  ? 502 OLA C C15 1 
HETATM 9990  C  C16 . OLA S 3 .   ? -45.952 -37.632 3.708   1.00 48.73  ? 502 OLA C C16 1 
HETATM 9991  C  C17 . OLA S 3 .   ? -44.796 -38.614 3.652   1.00 48.48  ? 502 OLA C C17 1 
HETATM 9992  C  C18 . OLA S 3 .   ? -43.532 -37.954 3.110   1.00 61.72  ? 502 OLA C C18 1 
HETATM 9993  C  C1  . PEG T 4 .   ? -41.781 -27.326 5.754   1.00 51.80  ? 503 PEG C C1  1 
HETATM 9994  O  O1  . PEG T 4 .   ? -40.608 -27.843 6.368   1.00 65.09  ? 503 PEG C O1  1 
HETATM 9995  C  C2  . PEG T 4 .   ? -42.938 -28.271 5.848   1.00 52.37  ? 503 PEG C C2  1 
HETATM 9996  O  O2  . PEG T 4 .   ? -42.794 -29.299 4.876   1.00 63.52  ? 503 PEG C O2  1 
HETATM 9997  C  C3  . PEG T 4 .   ? -41.967 -30.370 5.316   1.00 57.74  ? 503 PEG C C3  1 
HETATM 9998  C  C4  . PEG T 4 .   ? -41.741 -31.342 4.197   1.00 59.73  ? 503 PEG C C4  1 
HETATM 9999  O  O4  . PEG T 4 .   ? -40.817 -32.347 4.585   1.00 61.84  ? 503 PEG C O4  1 
HETATM 10000 C  C1  . GOL U 5 .   ? -71.835 -32.640 31.152  1.00 79.87  ? 504 GOL C C1  1 
HETATM 10001 O  O1  . GOL U 5 .   ? -71.625 -33.427 32.290  1.00 74.77  ? 504 GOL C O1  1 
HETATM 10002 C  C2  . GOL U 5 .   ? -72.491 -33.542 30.058  1.00 77.95  ? 504 GOL C C2  1 
HETATM 10003 O  O2  . GOL U 5 .   ? -73.675 -34.125 30.502  1.00 83.02  ? 504 GOL C O2  1 
HETATM 10004 C  C3  . GOL U 5 .   ? -71.415 -34.602 29.696  1.00 76.43  ? 504 GOL C C3  1 
HETATM 10005 O  O3  . GOL U 5 .   ? -70.182 -33.926 29.588  1.00 67.55  ? 504 GOL C O3  1 
HETATM 10006 CL CL  . CL  V 6 .   ? -65.495 -41.443 -16.387 1.00 40.82  ? 505 CL  C CL  1 
HETATM 10007 O  O   . HOH W 8 .   ? -25.020 -28.591 -1.028  1.00 43.20  ? 601 HOH A O   1 
HETATM 10008 O  O   . HOH W 8 .   ? -19.778 -20.979 41.645  1.00 34.81  ? 602 HOH A O   1 
HETATM 10009 O  O   . HOH W 8 .   ? -37.168 -10.832 26.447  1.00 45.56  ? 603 HOH A O   1 
HETATM 10010 O  O   . HOH W 8 .   ? -35.931 -12.666 -5.113  1.00 45.01  ? 604 HOH A O   1 
HETATM 10011 O  O   . HOH W 8 .   ? -3.225  -36.275 32.028  1.00 40.91  ? 605 HOH A O   1 
HETATM 10012 O  O   . HOH W 8 .   ? -1.265  -27.604 27.100  1.00 33.06  ? 606 HOH A O   1 
HETATM 10013 O  O   . HOH W 8 .   ? -10.154 -24.658 -2.229  1.00 37.83  ? 607 HOH A O   1 
HETATM 10014 O  O   . HOH W 8 .   ? -18.702 -49.732 20.130  1.00 55.47  ? 608 HOH A O   1 
HETATM 10015 O  O   . HOH W 8 .   ? -7.452  -47.300 21.474  1.00 36.33  ? 609 HOH A O   1 
HETATM 10016 O  O   . HOH W 8 .   ? -11.167 -45.500 28.073  1.00 38.94  ? 610 HOH A O   1 
HETATM 10017 O  O   . HOH W 8 .   ? -5.820  -8.333  29.132  1.00 42.70  ? 611 HOH A O   1 
HETATM 10018 O  O   . HOH W 8 .   ? -33.827 -16.786 24.112  1.00 26.16  ? 612 HOH A O   1 
HETATM 10019 O  O   . HOH W 8 .   ? -30.741 -22.086 -7.160  1.00 51.71  ? 613 HOH A O   1 
HETATM 10020 O  O   . HOH W 8 .   ? -22.118 -10.732 -5.232  1.00 43.62  ? 614 HOH A O   1 
HETATM 10021 O  O   . HOH W 8 .   ? -5.986  -0.472  17.212  1.00 49.34  ? 615 HOH A O   1 
HETATM 10022 O  O   . HOH W 8 .   ? -23.599 -5.951  11.560  1.00 27.48  ? 616 HOH A O   1 
HETATM 10023 O  O   . HOH W 8 .   ? -4.694  -40.606 28.963  1.00 33.46  ? 617 HOH A O   1 
HETATM 10024 O  O   . HOH W 8 .   ? -4.949  -14.626 43.116  1.00 39.84  ? 618 HOH A O   1 
HETATM 10025 O  O   . HOH W 8 .   ? -42.292 -12.076 11.934  1.00 34.79  ? 619 HOH A O   1 
HETATM 10026 O  O   . HOH W 8 .   ? -38.677 -21.632 35.220  1.00 38.25  ? 620 HOH A O   1 
HETATM 10027 O  O   . HOH W 8 .   ? -22.013 -1.479  17.457  1.00 41.06  ? 621 HOH A O   1 
HETATM 10028 O  O   . HOH W 8 .   ? -41.822 -8.379  36.342  1.00 45.25  ? 622 HOH A O   1 
HETATM 10029 O  O   . HOH W 8 .   ? -14.841 -0.996  19.094  1.00 35.48  ? 623 HOH A O   1 
HETATM 10030 O  O   . HOH W 8 .   ? 4.847   -24.017 0.912   1.00 50.08  ? 624 HOH A O   1 
HETATM 10031 O  O   . HOH W 8 .   ? -26.146 -17.465 21.112  1.00 22.28  ? 625 HOH A O   1 
HETATM 10032 O  O   . HOH W 8 .   ? -31.545 -31.441 1.699   1.00 54.24  ? 626 HOH A O   1 
HETATM 10033 O  O   . HOH W 8 .   ? -15.466 -19.873 -3.213  1.00 41.85  ? 627 HOH A O   1 
HETATM 10034 O  O   . HOH W 8 .   ? -23.988 -30.645 19.316  1.00 26.61  ? 628 HOH A O   1 
HETATM 10035 O  O   . HOH W 8 .   ? -37.405 -15.213 12.992  1.00 27.28  ? 629 HOH A O   1 
HETATM 10036 O  O   . HOH W 8 .   ? 4.279   -28.084 27.149  1.00 40.93  ? 630 HOH A O   1 
HETATM 10037 O  O   . HOH W 8 .   ? -36.432 -11.063 -1.603  1.00 49.59  ? 631 HOH A O   1 
HETATM 10038 O  O   . HOH W 8 .   ? -41.331 -8.949  41.186  1.00 47.63  ? 632 HOH A O   1 
HETATM 10039 O  O   . HOH W 8 .   ? -30.879 -29.787 5.883   1.00 44.63  ? 633 HOH A O   1 
HETATM 10040 O  O   . HOH W 8 .   ? -4.052  -8.447  31.703  1.00 47.18  ? 634 HOH A O   1 
HETATM 10041 O  O   . HOH W 8 .   ? -4.760  -9.660  10.201  1.00 46.68  ? 635 HOH A O   1 
HETATM 10042 O  O   . HOH W 8 .   ? -23.726 -22.268 -5.305  1.00 35.62  ? 636 HOH A O   1 
HETATM 10043 O  O   . HOH W 8 .   ? -19.126 -37.906 4.135   1.00 32.31  ? 637 HOH A O   1 
HETATM 10044 O  O   . HOH W 8 .   ? -36.071 -6.208  39.710  1.00 35.06  ? 638 HOH A O   1 
HETATM 10045 O  O   . HOH W 8 .   ? -36.251 -10.327 23.116  1.00 29.44  ? 639 HOH A O   1 
HETATM 10046 O  O   . HOH W 8 .   ? -13.067 0.294   12.765  1.00 34.93  ? 640 HOH A O   1 
HETATM 10047 O  O   . HOH W 8 .   ? 14.584  -21.045 16.979  1.00 31.71  ? 641 HOH A O   1 
HETATM 10048 O  O   . HOH W 8 .   ? -9.246  -13.041 19.400  1.00 24.18  ? 642 HOH A O   1 
HETATM 10049 O  O   . HOH W 8 .   ? -41.534 -15.118 1.938   1.00 47.13  ? 643 HOH A O   1 
HETATM 10050 O  O   . HOH W 8 .   ? -24.854 -33.251 35.723  1.00 43.25  ? 644 HOH A O   1 
HETATM 10051 O  O   . HOH W 8 .   ? -24.357 -25.485 39.463  1.00 43.39  ? 645 HOH A O   1 
HETATM 10052 O  O   . HOH W 8 .   ? -6.618  -11.964 22.254  1.00 40.77  ? 646 HOH A O   1 
HETATM 10053 O  O   . HOH W 8 .   ? -27.082 -15.375 22.564  1.00 23.53  ? 647 HOH A O   1 
HETATM 10054 O  O   . HOH W 8 .   ? -17.034 -2.828  1.492   1.00 36.59  ? 648 HOH A O   1 
HETATM 10055 O  O   . HOH W 8 .   ? -30.526 -16.706 -8.040  1.00 30.44  ? 649 HOH A O   1 
HETATM 10056 O  O   . HOH W 8 .   ? -4.042  -17.322 -0.252  1.00 43.73  ? 650 HOH A O   1 
HETATM 10057 O  O   . HOH W 8 .   ? 11.715  -19.404 18.333  1.00 27.45  ? 651 HOH A O   1 
HETATM 10058 O  O   . HOH W 8 .   ? -28.981 -5.141  -0.781  1.00 43.25  ? 652 HOH A O   1 
HETATM 10059 O  O   . HOH W 8 .   ? -21.764 -3.838  9.262   1.00 35.89  ? 653 HOH A O   1 
HETATM 10060 O  O   . HOH W 8 .   ? -9.267  -19.459 22.413  1.00 28.03  ? 654 HOH A O   1 
HETATM 10061 O  O   . HOH W 8 .   ? 2.297   -34.212 -0.693  1.00 53.94  ? 655 HOH A O   1 
HETATM 10062 O  O   . HOH W 8 .   ? -33.302 -25.328 31.691  1.00 35.70  ? 656 HOH A O   1 
HETATM 10063 O  O   . HOH W 8 .   ? -35.044 -22.422 3.145   1.00 36.39  ? 657 HOH A O   1 
HETATM 10064 O  O   . HOH W 8 .   ? -0.042  -24.563 3.866   1.00 32.00  ? 658 HOH A O   1 
HETATM 10065 O  O   . HOH W 8 .   ? 9.801   -29.779 18.061  1.00 36.60  ? 659 HOH A O   1 
HETATM 10066 O  O   . HOH W 8 .   ? -28.926 -6.960  10.693  1.00 36.98  ? 660 HOH A O   1 
HETATM 10067 O  O   . HOH W 8 .   ? -19.292 -23.863 7.542   1.00 26.02  ? 661 HOH A O   1 
HETATM 10068 O  O   . HOH W 8 .   ? -9.265  -20.488 -2.204  1.00 39.75  ? 662 HOH A O   1 
HETATM 10069 O  O   . HOH W 8 .   ? -34.021 -27.274 11.922  1.00 30.79  ? 663 HOH A O   1 
HETATM 10070 O  O   . HOH W 8 .   ? -9.264  -10.565 20.436  1.00 25.82  ? 664 HOH A O   1 
HETATM 10071 O  O   . HOH W 8 .   ? -28.473 -35.198 15.819  1.00 36.80  ? 665 HOH A O   1 
HETATM 10072 O  O   . HOH W 8 .   ? -4.152  -17.755 6.830   1.00 37.74  ? 666 HOH A O   1 
HETATM 10073 O  O   . HOH W 8 .   ? -32.913 -7.980  10.777  1.00 36.12  ? 667 HOH A O   1 
HETATM 10074 O  O   . HOH W 8 .   ? -4.165  -13.308 12.347  1.00 47.20  ? 668 HOH A O   1 
HETATM 10075 O  O   . HOH W 8 .   ? -24.426 -13.771 44.664  1.00 38.62  ? 669 HOH A O   1 
HETATM 10076 O  O   . HOH W 8 .   ? 1.570   -19.427 7.102   1.00 33.63  ? 670 HOH A O   1 
HETATM 10077 O  O   . HOH W 8 .   ? -27.011 -34.763 30.521  1.00 45.53  ? 671 HOH A O   1 
HETATM 10078 O  O   . HOH W 8 .   ? -40.958 -18.526 7.935   1.00 28.64  ? 672 HOH A O   1 
HETATM 10079 O  O   . HOH W 8 .   ? -1.956  -31.399 26.869  1.00 32.70  ? 673 HOH A O   1 
HETATM 10080 O  O   . HOH W 8 .   ? -2.196  -25.864 29.763  1.00 39.85  ? 674 HOH A O   1 
HETATM 10081 O  O   . HOH W 8 .   ? -27.000 -11.129 23.514  1.00 27.06  ? 675 HOH A O   1 
HETATM 10082 O  O   . HOH W 8 .   ? -4.210  -47.130 18.051  1.00 29.54  ? 676 HOH A O   1 
HETATM 10083 O  O   . HOH W 8 .   ? 8.818   -25.075 11.700  1.00 38.45  ? 677 HOH A O   1 
HETATM 10084 O  O   . HOH W 8 .   ? -24.726 -9.849  19.839  1.00 37.89  ? 678 HOH A O   1 
HETATM 10085 O  O   . HOH W 8 .   ? -6.568  -38.363 33.863  1.00 36.49  ? 679 HOH A O   1 
HETATM 10086 O  O   . HOH W 8 .   ? -33.853 -9.401  19.816  1.00 39.39  ? 680 HOH A O   1 
HETATM 10087 O  O   . HOH W 8 .   ? -14.316 -37.446 14.463  1.00 43.54  ? 681 HOH A O   1 
HETATM 10088 O  O   . HOH W 8 .   ? -24.815 -24.674 41.558  1.00 48.24  ? 682 HOH A O   1 
HETATM 10089 O  O   . HOH W 8 .   ? -12.397 -39.431 14.036  1.00 30.62  ? 683 HOH A O   1 
HETATM 10090 O  O   . HOH W 8 .   ? 4.653   -17.339 14.043  1.00 39.42  ? 684 HOH A O   1 
HETATM 10091 O  O   . HOH W 8 .   ? 1.666   -35.331 6.070   1.00 34.75  ? 685 HOH A O   1 
HETATM 10092 O  O   . HOH W 8 .   ? -18.939 -39.862 30.635  1.00 51.37  ? 686 HOH A O   1 
HETATM 10093 O  O   . HOH W 8 .   ? -11.048 -9.963  41.897  1.00 39.08  ? 687 HOH A O   1 
HETATM 10094 O  O   . HOH W 8 .   ? -1.269  -34.514 29.408  1.00 44.94  ? 688 HOH A O   1 
HETATM 10095 O  O   . HOH W 8 .   ? -9.799  -19.183 -8.888  1.00 46.20  ? 689 HOH A O   1 
HETATM 10096 O  O   . HOH W 8 .   ? -20.537 -30.944 23.006  1.00 25.44  ? 690 HOH A O   1 
HETATM 10097 O  O   . HOH W 8 .   ? -12.992 -24.136 38.735  1.00 47.57  ? 691 HOH A O   1 
HETATM 10098 O  O   . HOH W 8 .   ? -19.039 -32.638 -0.308  1.00 31.23  ? 692 HOH A O   1 
HETATM 10099 O  O   . HOH W 8 .   ? -18.231 -36.080 10.403  1.00 31.21  ? 693 HOH A O   1 
HETATM 10100 O  O   . HOH W 8 .   ? -35.357 -8.543  8.630   1.00 49.28  ? 694 HOH A O   1 
HETATM 10101 O  O   . HOH W 8 .   ? -23.119 -19.857 -7.360  1.00 41.35  ? 695 HOH A O   1 
HETATM 10102 O  O   . HOH W 8 .   ? -23.112 -35.971 11.784  1.00 32.08  ? 696 HOH A O   1 
HETATM 10103 O  O   . HOH W 8 .   ? -4.715  -41.821 11.977  1.00 45.35  ? 697 HOH A O   1 
HETATM 10104 O  O   . HOH W 8 .   ? -14.850 -5.931  19.029  1.00 28.73  ? 698 HOH A O   1 
HETATM 10105 O  O   . HOH W 8 .   ? -6.142  -32.027 -0.951  1.00 38.82  ? 699 HOH A O   1 
HETATM 10106 O  O   . HOH W 8 .   ? -18.169 -12.641 9.944   1.00 25.32  ? 700 HOH A O   1 
HETATM 10107 O  O   . HOH W 8 .   ? -21.078 -27.527 23.778  1.00 19.07  ? 701 HOH A O   1 
HETATM 10108 O  O   . HOH W 8 .   ? -32.898 -23.410 26.244  1.00 25.05  ? 702 HOH A O   1 
HETATM 10109 O  O   . HOH W 8 .   ? -16.399 -27.307 41.087  1.00 34.05  ? 703 HOH A O   1 
HETATM 10110 O  O   . HOH W 8 .   ? -9.990  -47.723 18.134  1.00 36.74  ? 704 HOH A O   1 
HETATM 10111 O  O   . HOH W 8 .   ? -20.614 -45.695 22.506  1.00 32.88  ? 705 HOH A O   1 
HETATM 10112 O  O   . HOH W 8 .   ? -3.955  -44.276 11.247  1.00 44.86  ? 706 HOH A O   1 
HETATM 10113 O  O   . HOH W 8 .   ? 1.890   -22.632 4.740   1.00 37.51  ? 707 HOH A O   1 
HETATM 10114 O  O   . HOH W 8 .   ? -30.896 -19.119 27.408  1.00 25.98  ? 708 HOH A O   1 
HETATM 10115 O  O   . HOH W 8 .   ? -33.923 -20.687 5.108   1.00 24.46  ? 709 HOH A O   1 
HETATM 10116 O  O   . HOH W 8 .   ? 4.356   -39.813 19.252  1.00 33.95  ? 710 HOH A O   1 
HETATM 10117 O  O   . HOH W 8 .   ? -24.505 -31.245 26.781  1.00 31.65  ? 711 HOH A O   1 
HETATM 10118 O  O   . HOH W 8 .   ? -13.282 -34.629 40.807  1.00 41.74  ? 712 HOH A O   1 
HETATM 10119 O  O   . HOH W 8 .   ? -0.607  -27.532 -1.064  1.00 41.83  ? 713 HOH A O   1 
HETATM 10120 O  O   . HOH W 8 .   ? -45.812 -17.214 13.405  1.00 34.17  ? 714 HOH A O   1 
HETATM 10121 O  O   . HOH W 8 .   ? -13.233 -24.803 25.264  1.00 21.88  ? 715 HOH A O   1 
HETATM 10122 O  O   . HOH W 8 .   ? -24.661 -26.290 0.955   1.00 25.81  ? 716 HOH A O   1 
HETATM 10123 O  O   . HOH W 8 .   ? -35.789 -15.667 10.802  1.00 26.43  ? 717 HOH A O   1 
HETATM 10124 O  O   . HOH W 8 .   ? -28.699 -6.827  16.951  1.00 56.15  ? 718 HOH A O   1 
HETATM 10125 O  O   . HOH W 8 .   ? -31.112 -27.548 38.195  1.00 47.41  ? 719 HOH A O   1 
HETATM 10126 O  O   . HOH W 8 .   ? -8.718  -46.658 25.533  1.00 31.79  ? 720 HOH A O   1 
HETATM 10127 O  O   . HOH W 8 .   ? -35.422 -24.176 16.142  1.00 33.11  ? 721 HOH A O   1 
HETATM 10128 O  O   . HOH W 8 .   ? -24.762 -36.296 2.548   1.00 38.14  ? 722 HOH A O   1 
HETATM 10129 O  O   . HOH W 8 .   ? -14.029 -42.472 20.558  1.00 41.86  ? 723 HOH A O   1 
HETATM 10130 O  O   . HOH W 8 .   ? -13.294 -35.417 10.092  1.00 24.55  ? 724 HOH A O   1 
HETATM 10131 O  O   . HOH W 8 .   ? -40.244 -16.507 28.389  1.00 42.31  ? 725 HOH A O   1 
HETATM 10132 O  O   . HOH W 8 .   ? -37.781 -19.739 4.356   1.00 37.36  ? 726 HOH A O   1 
HETATM 10133 O  O   . HOH W 8 .   ? -0.933  -16.230 24.117  1.00 31.78  ? 727 HOH A O   1 
HETATM 10134 O  O   . HOH W 8 .   ? -11.630 -35.773 1.010   1.00 32.76  ? 728 HOH A O   1 
HETATM 10135 O  O   . HOH W 8 .   ? -22.950 -29.148 13.436  1.00 24.89  ? 729 HOH A O   1 
HETATM 10136 O  O   . HOH W 8 .   ? -36.348 -12.440 12.428  1.00 36.19  ? 730 HOH A O   1 
HETATM 10137 O  O   . HOH W 8 .   ? -2.761  -39.774 11.889  1.00 23.34  ? 731 HOH A O   1 
HETATM 10138 O  O   . HOH W 8 .   ? -11.967 -17.117 48.640  1.00 31.03  ? 732 HOH A O   1 
HETATM 10139 O  O   . HOH W 8 .   ? 4.785   -43.487 21.679  1.00 48.23  ? 733 HOH A O   1 
HETATM 10140 O  O   . HOH W 8 .   ? -36.562 -17.319 24.152  1.00 25.59  ? 734 HOH A O   1 
HETATM 10141 O  O   . HOH W 8 .   ? -8.143  -22.331 -3.471  1.00 44.90  ? 735 HOH A O   1 
HETATM 10142 O  O   . HOH W 8 .   ? -36.875 -16.050 26.848  1.00 31.57  ? 736 HOH A O   1 
HETATM 10143 O  O   . HOH W 8 .   ? -23.498 -4.415  -0.063  1.00 37.39  ? 737 HOH A O   1 
HETATM 10144 O  O   . HOH W 8 .   ? -21.985 -32.001 25.006  1.00 27.08  ? 738 HOH A O   1 
HETATM 10145 O  O   . HOH W 8 .   ? -30.200 -27.551 30.834  1.00 38.25  ? 739 HOH A O   1 
HETATM 10146 O  O   . HOH W 8 .   ? -22.111 -29.011 0.277   1.00 37.62  ? 740 HOH A O   1 
HETATM 10147 O  O   . HOH W 8 .   ? -24.199 -28.603 17.429  1.00 21.20  ? 741 HOH A O   1 
HETATM 10148 O  O   . HOH W 8 .   ? -37.748 -14.936 -4.842  1.00 51.30  ? 742 HOH A O   1 
HETATM 10149 O  O   . HOH W 8 .   ? -35.882 -11.959 42.952  1.00 45.53  ? 743 HOH A O   1 
HETATM 10150 O  O   . HOH W 8 .   ? -32.909 -10.059 12.948  1.00 33.02  ? 744 HOH A O   1 
HETATM 10151 O  O   . HOH W 8 .   ? -22.188 -12.584 11.132  1.00 22.30  ? 745 HOH A O   1 
HETATM 10152 O  O   . HOH W 8 .   ? -28.283 -35.190 18.882  1.00 48.34  ? 746 HOH A O   1 
HETATM 10153 O  O   . HOH W 8 .   ? -35.479 -29.246 24.698  1.00 50.92  ? 747 HOH A O   1 
HETATM 10154 O  O   . HOH W 8 .   ? -29.650 -24.529 24.195  1.00 19.34  ? 748 HOH A O   1 
HETATM 10155 O  O   . HOH W 8 .   ? -8.956  -9.617  25.848  1.00 27.29  ? 749 HOH A O   1 
HETATM 10156 O  O   . HOH W 8 .   ? -36.218 -20.026 21.380  1.00 35.56  ? 750 HOH A O   1 
HETATM 10157 O  O   . HOH W 8 .   ? -7.322  -5.057  25.644  1.00 34.44  ? 751 HOH A O   1 
HETATM 10158 O  O   . HOH W 8 .   ? -6.732  -34.535 5.480   1.00 31.43  ? 752 HOH A O   1 
HETATM 10159 O  O   . HOH W 8 .   ? -9.024  -12.679 43.598  1.00 43.43  ? 753 HOH A O   1 
HETATM 10160 O  O   . HOH W 8 .   ? -6.467  -25.422 2.294   1.00 26.43  ? 754 HOH A O   1 
HETATM 10161 O  O   . HOH W 8 .   ? -29.108 -8.587  21.490  1.00 46.64  ? 755 HOH A O   1 
HETATM 10162 O  O   . HOH W 8 .   ? -22.739 -36.942 9.262   1.00 27.25  ? 756 HOH A O   1 
HETATM 10163 O  O   . HOH W 8 .   ? -32.713 -17.247 26.658  1.00 23.52  ? 757 HOH A O   1 
HETATM 10164 O  O   . HOH W 8 .   ? -11.658 -18.275 35.806  1.00 23.22  ? 758 HOH A O   1 
HETATM 10165 O  O   . HOH W 8 .   ? -26.086 -13.667 24.704  1.00 32.20  ? 759 HOH A O   1 
HETATM 10166 O  O   . HOH W 8 .   ? -24.429 -6.781  33.953  1.00 28.82  ? 760 HOH A O   1 
HETATM 10167 O  O   . HOH W 8 .   ? -8.796  -38.828 35.594  1.00 47.59  ? 761 HOH A O   1 
HETATM 10168 O  O   . HOH W 8 .   ? -15.241 -42.538 27.702  1.00 28.20  ? 762 HOH A O   1 
HETATM 10169 O  O   . HOH W 8 .   ? 8.325   -27.429 25.087  1.00 30.94  ? 763 HOH A O   1 
HETATM 10170 O  O   . HOH W 8 .   ? -45.333 -18.002 8.973   1.00 36.04  ? 764 HOH A O   1 
HETATM 10171 O  O   . HOH W 8 .   ? -41.583 -10.813 32.576  1.00 40.30  ? 765 HOH A O   1 
HETATM 10172 O  O   . HOH W 8 .   ? 0.647   -25.203 26.831  1.00 41.03  ? 766 HOH A O   1 
HETATM 10173 O  O   . HOH W 8 .   ? -25.810 -7.035  -5.150  1.00 43.90  ? 767 HOH A O   1 
HETATM 10174 O  O   . HOH W 8 .   ? -25.000 -8.457  17.722  1.00 34.79  ? 768 HOH A O   1 
HETATM 10175 O  O   . HOH W 8 .   ? -2.944  -37.542 28.201  1.00 38.26  ? 769 HOH A O   1 
HETATM 10176 O  O   . HOH W 8 .   ? -1.757  -41.708 10.018  1.00 43.12  ? 770 HOH A O   1 
HETATM 10177 O  O   . HOH W 8 .   ? -7.268  -35.382 7.974   1.00 27.98  ? 771 HOH A O   1 
HETATM 10178 O  O   . HOH W 8 .   ? -40.628 -9.959  38.197  1.00 37.91  ? 772 HOH A O   1 
HETATM 10179 O  O   . HOH W 8 .   ? -2.826  -23.690 0.154   1.00 50.79  ? 773 HOH A O   1 
HETATM 10180 O  O   . HOH W 8 .   ? -33.861 -8.436  -0.345  1.00 35.63  ? 774 HOH A O   1 
HETATM 10181 O  O   . HOH W 8 .   ? 8.676   -20.626 10.914  1.00 46.54  ? 775 HOH A O   1 
HETATM 10182 O  O   . HOH W 8 .   ? -30.964 -24.796 38.247  1.00 41.80  ? 776 HOH A O   1 
HETATM 10183 O  O   . HOH W 8 .   ? -9.507  -18.760 13.128  1.00 26.03  ? 777 HOH A O   1 
HETATM 10184 O  O   . HOH W 8 .   ? 9.338   -36.433 1.261   1.00 47.57  ? 778 HOH A O   1 
HETATM 10185 O  O   . HOH W 8 .   ? 11.064  -29.648 6.987   1.00 44.87  ? 779 HOH A O   1 
HETATM 10186 O  O   . HOH W 8 .   ? -5.658  -4.243  23.830  1.00 39.15  ? 780 HOH A O   1 
HETATM 10187 O  O   . HOH W 8 .   ? -13.488 -17.561 31.808  1.00 30.41  ? 781 HOH A O   1 
HETATM 10188 O  O   . HOH W 8 .   ? -6.678  -14.078 19.426  1.00 30.79  ? 782 HOH A O   1 
HETATM 10189 O  O   . HOH W 8 .   ? 8.592   -27.003 13.552  1.00 30.79  ? 783 HOH A O   1 
HETATM 10190 O  O   . HOH W 8 .   ? -4.440  -23.569 4.018   1.00 31.63  ? 784 HOH A O   1 
HETATM 10191 O  O   . HOH W 8 .   ? -21.389 -18.139 17.277  1.00 36.10  ? 785 HOH A O   1 
HETATM 10192 O  O   . HOH W 8 .   ? 9.552   -18.417 12.541  1.00 32.99  ? 786 HOH A O   1 
HETATM 10193 O  O   . HOH W 8 .   ? -5.950  -14.976 3.380   1.00 33.96  ? 787 HOH A O   1 
HETATM 10194 O  O   . HOH W 8 .   ? -7.829  -10.625 4.025   1.00 36.50  ? 788 HOH A O   1 
HETATM 10195 O  O   . HOH W 8 .   ? -25.740 -29.527 28.605  1.00 23.93  ? 789 HOH A O   1 
HETATM 10196 O  O   . HOH W 8 .   ? 7.045   -34.774 2.718   1.00 43.83  ? 790 HOH A O   1 
HETATM 10197 O  O   . HOH W 8 .   ? -25.102 -4.232  9.837   1.00 34.22  ? 791 HOH A O   1 
HETATM 10198 O  O   . HOH W 8 .   ? -15.177 -23.060 24.674  1.00 22.78  ? 792 HOH A O   1 
HETATM 10199 O  O   . HOH W 8 .   ? -20.731 -25.494 46.541  1.00 36.97  ? 793 HOH A O   1 
HETATM 10200 O  O   . HOH W 8 .   ? -13.451 -22.522 27.234  1.00 21.84  ? 794 HOH A O   1 
HETATM 10201 O  O   . HOH W 8 .   ? 4.466   -35.443 19.782  1.00 25.46  ? 795 HOH A O   1 
HETATM 10202 O  O   . HOH W 8 .   ? -8.023  -42.324 15.718  1.00 21.93  ? 796 HOH A O   1 
HETATM 10203 O  O   . HOH W 8 .   ? 6.682   -31.614 19.090  1.00 43.79  ? 797 HOH A O   1 
HETATM 10204 O  O   . HOH W 8 .   ? -16.674 -38.647 30.319  1.00 45.47  ? 798 HOH A O   1 
HETATM 10205 O  O   . HOH W 8 .   ? -31.570 -20.942 25.405  1.00 17.31  ? 799 HOH A O   1 
HETATM 10206 O  O   . HOH W 8 .   ? -32.719 -23.182 5.991   1.00 26.29  ? 800 HOH A O   1 
HETATM 10207 O  O   . HOH W 8 .   ? -19.663 -19.048 39.760  1.00 31.88  ? 801 HOH A O   1 
HETATM 10208 O  O   . HOH W 8 .   ? -37.699 -22.553 21.774  1.00 44.65  ? 802 HOH A O   1 
HETATM 10209 O  O   . HOH W 8 .   ? -1.141  -13.527 31.193  1.00 34.55  ? 803 HOH A O   1 
HETATM 10210 O  O   . HOH W 8 .   ? 2.036   -33.987 3.855   1.00 44.97  ? 804 HOH A O   1 
HETATM 10211 O  O   . HOH W 8 .   ? -29.611 -30.896 20.928  1.00 33.45  ? 805 HOH A O   1 
HETATM 10212 O  O   . HOH W 8 .   ? -24.332 -9.133  5.380   1.00 26.77  ? 806 HOH A O   1 
HETATM 10213 O  O   . HOH W 8 .   ? -22.398 -21.514 40.280  1.00 31.73  ? 807 HOH A O   1 
HETATM 10214 O  O   . HOH W 8 .   ? -15.765 -26.586 -4.905  1.00 47.68  ? 808 HOH A O   1 
HETATM 10215 O  O   . HOH W 8 .   ? -23.123 -30.543 39.985  1.00 47.95  ? 809 HOH A O   1 
HETATM 10216 O  O   . HOH W 8 .   ? -41.363 -12.868 39.179  1.00 48.28  ? 810 HOH A O   1 
HETATM 10217 O  O   . HOH W 8 .   ? -13.026 -35.279 7.381   1.00 28.81  ? 811 HOH A O   1 
HETATM 10218 O  O   . HOH W 8 .   ? -4.600  -43.327 28.663  1.00 39.07  ? 812 HOH A O   1 
HETATM 10219 O  O   . HOH W 8 .   ? -24.316 -17.775 -11.384 1.00 41.64  ? 813 HOH A O   1 
HETATM 10220 O  O   . HOH W 8 .   ? 12.738  -19.408 15.539  1.00 30.99  ? 814 HOH A O   1 
HETATM 10221 O  O   . HOH W 8 .   ? -4.968  -47.261 20.896  1.00 45.53  ? 815 HOH A O   1 
HETATM 10222 O  O   . HOH W 8 .   ? -24.906 -28.427 2.841   1.00 37.79  ? 816 HOH A O   1 
HETATM 10223 O  O   . HOH W 8 .   ? -20.588 -16.144 -6.751  1.00 52.11  ? 817 HOH A O   1 
HETATM 10224 O  O   . HOH W 8 .   ? -18.572 -35.373 33.276  1.00 40.37  ? 818 HOH A O   1 
HETATM 10225 O  O   . HOH W 8 .   ? -15.507 -6.983  47.107  1.00 48.74  ? 819 HOH A O   1 
HETATM 10226 O  O   . HOH W 8 .   ? 0.169   -13.178 18.394  1.00 48.66  ? 820 HOH A O   1 
HETATM 10227 O  O   . HOH W 8 .   ? -41.369 -9.918  15.471  1.00 39.90  ? 821 HOH A O   1 
HETATM 10228 O  O   . HOH W 8 .   ? -7.434  -32.070 38.436  1.00 29.12  ? 822 HOH A O   1 
HETATM 10229 O  O   . HOH W 8 .   ? -19.676 -37.031 15.263  1.00 37.56  ? 823 HOH A O   1 
HETATM 10230 O  O   . HOH W 8 .   ? -20.953 -34.476 35.878  1.00 40.53  ? 824 HOH A O   1 
HETATM 10231 O  O   . HOH W 8 .   ? -30.159 -19.128 -6.987  1.00 36.87  ? 825 HOH A O   1 
HETATM 10232 O  O   . HOH W 8 .   ? -12.884 -8.426  0.412   1.00 49.55  ? 826 HOH A O   1 
HETATM 10233 O  O   . HOH W 8 .   ? -17.711 -21.640 49.465  1.00 38.22  ? 827 HOH A O   1 
HETATM 10234 O  O   . HOH W 8 .   ? -41.277 -11.385 1.733   1.00 46.43  ? 828 HOH A O   1 
HETATM 10235 O  O   . HOH W 8 .   ? -33.412 -6.541  1.776   1.00 37.90  ? 829 HOH A O   1 
HETATM 10236 O  O   . HOH W 8 .   ? -8.420  -4.597  10.142  1.00 42.86  ? 830 HOH A O   1 
HETATM 10237 O  O   . HOH W 8 .   ? -16.697 -5.673  0.794   1.00 39.98  ? 831 HOH A O   1 
HETATM 10238 O  O   . HOH W 8 .   ? -9.368  -10.316 28.355  1.00 33.46  ? 832 HOH A O   1 
HETATM 10239 O  O   . HOH W 8 .   ? -13.558 -20.101 35.528  1.00 30.97  ? 833 HOH A O   1 
HETATM 10240 O  O   . HOH W 8 .   ? -38.331 -17.419 0.745   1.00 42.22  ? 834 HOH A O   1 
HETATM 10241 O  O   . HOH W 8 .   ? -19.006 -12.010 -3.958  1.00 33.09  ? 835 HOH A O   1 
HETATM 10242 O  O   . HOH W 8 .   ? -36.292 -11.328 19.872  1.00 38.03  ? 836 HOH A O   1 
HETATM 10243 O  O   . HOH W 8 .   ? -29.383 -35.072 11.663  1.00 36.96  ? 837 HOH A O   1 
HETATM 10244 O  O   . HOH W 8 .   ? -14.813 -1.175  35.923  1.00 41.30  ? 838 HOH A O   1 
HETATM 10245 O  O   . HOH W 8 .   ? 12.288  -31.360 5.376   1.00 42.40  ? 839 HOH A O   1 
HETATM 10246 O  O   . HOH W 8 .   ? 9.730   -24.116 25.371  1.00 30.83  ? 840 HOH A O   1 
HETATM 10247 O  O   . HOH W 8 .   ? -5.843  -12.915 7.809   1.00 32.46  ? 841 HOH A O   1 
HETATM 10248 O  O   . HOH W 8 .   ? -4.290  -13.269 9.932   1.00 45.02  ? 842 HOH A O   1 
HETATM 10249 O  O   . HOH W 8 .   ? -27.022 -4.214  25.679  1.00 52.56  ? 843 HOH A O   1 
HETATM 10250 O  O   . HOH W 8 .   ? -2.448  -21.445 -1.109  1.00 56.21  ? 844 HOH A O   1 
HETATM 10251 O  O   . HOH W 8 .   ? 9.139   -21.628 4.242   1.00 43.17  ? 845 HOH A O   1 
HETATM 10252 O  O   . HOH W 8 .   ? -30.451 -5.216  3.503   1.00 39.00  ? 846 HOH A O   1 
HETATM 10253 O  O   . HOH W 8 .   ? -20.721 -9.909  -3.063  1.00 32.86  ? 847 HOH A O   1 
HETATM 10254 O  O   . HOH W 8 .   ? -8.057  -43.856 11.986  1.00 42.15  ? 848 HOH A O   1 
HETATM 10255 O  O   . HOH W 8 .   ? -28.191 -36.468 22.027  1.00 48.31  ? 849 HOH A O   1 
HETATM 10256 O  O   . HOH W 8 .   ? -28.040 -30.551 -0.527  1.00 56.49  ? 850 HOH A O   1 
HETATM 10257 O  O   . HOH W 8 .   ? -7.485  -9.513  6.550   1.00 32.69  ? 851 HOH A O   1 
HETATM 10258 O  O   . HOH W 8 .   ? -35.673 -23.823 25.561  1.00 34.83  ? 852 HOH A O   1 
HETATM 10259 O  O   . HOH W 8 .   ? 6.583   -33.012 16.499  1.00 25.78  ? 853 HOH A O   1 
HETATM 10260 O  O   . HOH W 8 .   ? -36.470 -23.330 28.165  1.00 30.06  ? 854 HOH A O   1 
HETATM 10261 O  O   . HOH W 8 .   ? 0.686   -12.207 27.581  1.00 45.55  ? 855 HOH A O   1 
HETATM 10262 O  O   . HOH W 8 .   ? -39.079 -19.245 24.726  1.00 44.22  ? 856 HOH A O   1 
HETATM 10263 O  O   . HOH W 8 .   ? -10.454 -41.963 10.410  1.00 57.74  ? 857 HOH A O   1 
HETATM 10264 O  O   . HOH W 8 .   ? -6.581  -24.724 29.922  1.00 40.04  ? 858 HOH A O   1 
HETATM 10265 O  O   . HOH W 8 .   ? -2.445  -43.387 26.182  1.00 42.39  ? 859 HOH A O   1 
HETATM 10266 O  O   . HOH W 8 .   ? -16.547 -28.970 -4.421  1.00 54.37  ? 860 HOH A O   1 
HETATM 10267 O  O   . HOH W 8 .   ? -35.882 -7.196  25.470  1.00 37.36  ? 861 HOH A O   1 
HETATM 10268 O  O   . HOH W 8 .   ? -22.023 -18.340 -5.218  1.00 38.35  ? 862 HOH A O   1 
HETATM 10269 O  O   . HOH W 8 .   ? -8.493  -35.265 42.196  1.00 46.50  ? 863 HOH A O   1 
HETATM 10270 O  O   . HOH W 8 .   ? -10.821 -34.521 40.884  1.00 41.74  ? 864 HOH A O   1 
HETATM 10271 O  O   . HOH W 8 .   ? -6.891  -42.177 13.538  1.00 35.74  ? 865 HOH A O   1 
HETATM 10272 O  O   . HOH W 8 .   ? 0.172   -21.873 28.752  1.00 32.45  ? 866 HOH A O   1 
HETATM 10273 O  O   . HOH W 8 .   ? -30.666 -34.718 15.096  1.00 54.68  ? 867 HOH A O   1 
HETATM 10274 O  O   . HOH W 8 .   ? -4.270  -8.927  13.190  1.00 40.75  ? 868 HOH A O   1 
HETATM 10275 O  O   . HOH W 8 .   ? -35.018 -25.296 29.440  1.00 39.57  ? 869 HOH A O   1 
HETATM 10276 O  O   . HOH W 8 .   ? -17.472 -39.697 14.789  1.00 55.06  ? 870 HOH A O   1 
HETATM 10277 O  O   . HOH W 8 .   ? -32.738 -26.062 25.305  1.00 25.32  ? 871 HOH A O   1 
HETATM 10278 O  O   . HOH W 8 .   ? -24.538 -7.821  20.963  1.00 42.73  ? 872 HOH A O   1 
HETATM 10279 O  O   . HOH W 8 .   ? 4.306   -23.196 4.279   1.00 42.88  ? 873 HOH A O   1 
HETATM 10280 O  O   . HOH W 8 .   ? -24.553 -28.017 39.933  1.00 34.86  ? 874 HOH A O   1 
HETATM 10281 O  O   . HOH W 8 .   ? -28.212 -29.572 29.578  1.00 35.67  ? 875 HOH A O   1 
HETATM 10282 O  O   . HOH W 8 .   ? -7.689  -40.075 40.526  1.00 50.06  ? 876 HOH A O   1 
HETATM 10283 O  O   . HOH W 8 .   ? -9.907  -3.301  3.649   1.00 42.52  ? 877 HOH A O   1 
HETATM 10284 O  O   . HOH W 8 .   ? -8.652  -35.714 1.349   1.00 40.45  ? 878 HOH A O   1 
HETATM 10285 O  O   . HOH W 8 .   ? -1.176  -51.127 16.585  1.00 49.56  ? 879 HOH A O   1 
HETATM 10286 O  O   . HOH W 8 .   ? -1.743  -16.255 31.736  1.00 31.07  ? 880 HOH A O   1 
HETATM 10287 O  O   . HOH W 8 .   ? -42.541 -23.355 13.615  1.00 44.04  ? 881 HOH A O   1 
HETATM 10288 O  O   . HOH W 8 .   ? -5.799  -37.551 41.799  1.00 35.82  ? 882 HOH A O   1 
HETATM 10289 O  O   . HOH W 8 .   ? -23.918 -35.957 32.460  1.00 29.42  ? 883 HOH A O   1 
HETATM 10290 O  O   . HOH W 8 .   ? -23.297 -36.835 15.532  1.00 25.83  ? 884 HOH A O   1 
HETATM 10291 O  O   . HOH W 8 .   ? -7.509  -49.393 15.626  1.00 38.93  ? 885 HOH A O   1 
HETATM 10292 O  O   . HOH W 8 .   ? -10.600 -13.570 49.738  1.00 55.04  ? 886 HOH A O   1 
HETATM 10293 O  O   . HOH W 8 .   ? -22.504 -18.026 14.736  1.00 35.48  ? 887 HOH A O   1 
HETATM 10294 O  O   . HOH W 8 .   ? -38.435 -22.116 10.502  1.00 37.95  ? 888 HOH A O   1 
HETATM 10295 O  O   . HOH W 8 .   ? 3.902   -41.044 16.347  1.00 24.00  ? 889 HOH A O   1 
HETATM 10296 O  O   . HOH W 8 .   ? -2.283  -14.903 20.981  1.00 51.53  ? 890 HOH A O   1 
HETATM 10297 O  O   . HOH W 8 .   ? -10.513 -40.800 32.161  1.00 49.16  ? 891 HOH A O   1 
HETATM 10298 O  O   . HOH W 8 .   ? -24.382 -3.664  27.196  1.00 50.58  ? 892 HOH A O   1 
HETATM 10299 O  O   . HOH W 8 .   ? -30.435 -3.696  5.748   1.00 52.51  ? 893 HOH A O   1 
HETATM 10300 O  O   . HOH W 8 .   ? -6.767  -26.608 33.816  1.00 47.31  ? 894 HOH A O   1 
HETATM 10301 O  O   . HOH W 8 .   ? 9.481   -37.358 -2.138  1.00 54.44  ? 895 HOH A O   1 
HETATM 10302 O  O   . HOH W 8 .   ? -11.856 -24.921 29.047  1.00 34.85  ? 896 HOH A O   1 
HETATM 10303 O  O   . HOH W 8 .   ? 8.131   -23.691 27.596  1.00 35.87  ? 897 HOH A O   1 
HETATM 10304 O  O   . HOH W 8 .   ? -9.065  -23.603 30.258  1.00 38.22  ? 898 HOH A O   1 
HETATM 10305 O  O   . HOH W 8 .   ? -16.165 -35.682 40.370  1.00 49.40  ? 899 HOH A O   1 
HETATM 10306 O  O   . HOH W 8 .   ? 0.557   -39.160 26.015  1.00 18.62  ? 900 HOH A O   1 
HETATM 10307 O  O   . HOH W 8 .   ? -19.615 0.776   4.573   1.00 44.27  ? 901 HOH A O   1 
HETATM 10308 O  O   . HOH W 8 .   ? 12.052  -22.295 24.232  1.00 20.21  ? 902 HOH A O   1 
HETATM 10309 O  O   . HOH W 8 .   ? -20.802 -2.191  24.365  1.00 33.96  ? 903 HOH A O   1 
HETATM 10310 O  O   . HOH W 8 .   ? -12.753 -6.517  46.913  1.00 54.87  ? 904 HOH A O   1 
HETATM 10311 O  O   . HOH W 8 .   ? -3.930  -14.955 23.231  1.00 47.20  ? 905 HOH A O   1 
HETATM 10312 O  O   . HOH W 8 .   ? -1.312  -41.179 27.658  1.00 38.68  ? 906 HOH A O   1 
HETATM 10313 O  O   . HOH W 8 .   ? -14.464 -37.591 4.173   1.00 47.26  ? 907 HOH A O   1 
HETATM 10314 O  O   . HOH W 8 .   ? 4.844   -18.683 10.958  1.00 28.60  ? 908 HOH A O   1 
HETATM 10315 O  O   . HOH W 8 .   ? -11.170 -37.069 10.445  1.00 32.23  ? 909 HOH A O   1 
HETATM 10316 O  O   . HOH W 8 .   ? -37.947 -21.784 6.151   1.00 43.71  ? 910 HOH A O   1 
HETATM 10317 O  O   . HOH W 8 .   ? -29.590 -5.141  38.064  1.00 47.08  ? 911 HOH A O   1 
HETATM 10318 O  O   . HOH W 8 .   ? 0.275   -15.726 14.151  1.00 43.48  ? 912 HOH A O   1 
HETATM 10319 O  O   . HOH W 8 .   ? -23.440 -1.732  10.529  1.00 52.85  ? 913 HOH A O   1 
HETATM 10320 O  O   . HOH W 8 .   ? -25.502 -38.576 6.645   1.00 42.01  ? 914 HOH A O   1 
HETATM 10321 O  O   . HOH W 8 .   ? -35.933 -25.086 8.579   1.00 42.48  ? 915 HOH A O   1 
HETATM 10322 O  O   . HOH W 8 .   ? -26.400 -40.779 19.964  1.00 48.24  ? 916 HOH A O   1 
HETATM 10323 O  O   . HOH W 8 .   ? -38.511 -20.125 1.959   1.00 50.20  ? 917 HOH A O   1 
HETATM 10324 O  O   . HOH W 8 .   ? -31.547 -17.643 -10.562 1.00 48.88  ? 918 HOH A O   1 
HETATM 10325 O  O   . HOH W 8 .   ? -13.635 0.486   17.151  1.00 48.58  ? 919 HOH A O   1 
HETATM 10326 O  O   . HOH W 8 .   ? -7.821  -8.053  2.825   1.00 50.56  ? 920 HOH A O   1 
HETATM 10327 O  O   . HOH W 8 .   ? 5.590   -38.362 16.398  1.00 41.38  ? 921 HOH A O   1 
HETATM 10328 O  O   . HOH W 8 .   ? -20.000 -1.146  19.577  1.00 39.67  ? 922 HOH A O   1 
HETATM 10329 O  O   . HOH W 8 .   ? -2.202  -19.299 0.631   1.00 53.87  ? 923 HOH A O   1 
HETATM 10330 O  O   . HOH W 8 .   ? -22.122 -36.737 1.349   1.00 56.27  ? 924 HOH A O   1 
HETATM 10331 O  O   . HOH W 8 .   ? 4.572   -36.340 3.449   1.00 53.32  ? 925 HOH A O   1 
HETATM 10332 O  O   . HOH W 8 .   ? -19.045 -5.402  -1.282  1.00 50.10  ? 926 HOH A O   1 
HETATM 10333 O  O   . HOH W 8 .   ? -20.034 -36.911 8.639   1.00 30.76  ? 927 HOH A O   1 
HETATM 10334 O  O   . HOH W 8 .   ? -7.082  -7.838  26.338  1.00 35.37  ? 928 HOH A O   1 
HETATM 10335 O  O   . HOH W 8 .   ? -30.197 -32.319 5.205   1.00 51.11  ? 929 HOH A O   1 
HETATM 10336 O  O   . HOH W 8 .   ? -12.556 -35.648 -1.421  1.00 48.48  ? 930 HOH A O   1 
HETATM 10337 O  O   . HOH W 8 .   ? -2.554  -39.514 29.620  1.00 43.47  ? 931 HOH A O   1 
HETATM 10338 O  O   . HOH W 8 .   ? -33.836 -27.777 -4.270  1.00 44.61  ? 932 HOH A O   1 
HETATM 10339 O  O   . HOH W 8 .   ? -41.646 -20.635 20.612  1.00 48.08  ? 933 HOH A O   1 
HETATM 10340 O  O   . HOH W 8 .   ? -20.825 -17.106 19.591  1.00 49.30  ? 934 HOH A O   1 
HETATM 10341 O  O   . HOH W 8 .   ? 1.169   -20.246 3.443   1.00 43.46  ? 935 HOH A O   1 
HETATM 10342 O  O   . HOH W 8 .   ? -34.464 -25.007 5.971   1.00 39.75  ? 936 HOH A O   1 
HETATM 10343 O  O   . HOH W 8 .   ? -1.724  -20.640 3.095   1.00 48.75  ? 937 HOH A O   1 
HETATM 10344 O  O   . HOH W 8 .   ? -23.606 -39.247 8.240   1.00 39.59  ? 938 HOH A O   1 
HETATM 10345 O  O   . HOH W 8 .   ? -36.520 -27.133 9.979   1.00 48.58  ? 939 HOH A O   1 
HETATM 10346 O  O   . HOH W 8 .   ? -30.701 -5.429  12.385  1.00 43.66  ? 940 HOH A O   1 
HETATM 10347 O  O   . HOH W 8 .   ? 13.290  -30.367 2.773   1.00 52.21  ? 941 HOH A O   1 
HETATM 10348 O  O   . HOH W 8 .   ? -22.751 -31.552 -2.568  1.00 56.60  ? 942 HOH A O   1 
HETATM 10349 O  O   . HOH W 8 .   ? -7.776  -36.912 3.594   1.00 47.22  ? 943 HOH A O   1 
HETATM 10350 O  O   . HOH W 8 .   ? -36.889 -10.927 14.605  1.00 43.42  ? 944 HOH A O   1 
HETATM 10351 O  O   . HOH W 8 .   ? -2.231  -23.146 2.913   1.00 39.51  ? 945 HOH A O   1 
HETATM 10352 O  O   . HOH W 8 .   ? -12.663 -24.842 -5.758  1.00 63.16  ? 946 HOH A O   1 
HETATM 10353 O  O   . HOH W 8 .   ? -36.748 -26.193 15.383  1.00 42.25  ? 947 HOH A O   1 
HETATM 10354 O  O   . HOH W 8 .   ? -15.377 -41.657 14.184  1.00 57.48  ? 948 HOH A O   1 
HETATM 10355 O  O   . HOH W 8 .   ? 9.485   -31.944 19.742  1.00 43.47  ? 949 HOH A O   1 
HETATM 10356 O  O   . HOH W 8 .   ? -20.527 -30.414 -1.466  1.00 40.17  ? 950 HOH A O   1 
HETATM 10357 O  O   . HOH W 8 .   ? -20.622 -35.687 13.423  1.00 37.49  ? 951 HOH A O   1 
HETATM 10358 O  O   . HOH W 8 .   ? -5.748  -12.133 3.217   1.00 47.74  ? 952 HOH A O   1 
HETATM 10359 O  O   . HOH W 8 .   ? -5.276  -15.068 6.123   1.00 38.57  ? 953 HOH A O   1 
HETATM 10360 O  O   . HOH W 8 .   ? -27.829 -4.825  9.801   1.00 42.32  ? 954 HOH A O   1 
HETATM 10361 O  O   . HOH W 8 .   ? -4.490  -35.347 5.083   1.00 44.37  ? 955 HOH A O   1 
HETATM 10362 O  O   . HOH W 8 .   ? -20.705 -34.985 -0.395  1.00 50.02  ? 956 HOH A O   1 
HETATM 10363 O  O   . HOH W 8 .   ? -14.876 -7.127  -0.121  1.00 54.90  ? 957 HOH A O   1 
HETATM 10364 O  O   . HOH W 8 .   ? -16.387 -38.848 3.337   1.00 41.35  ? 958 HOH A O   1 
HETATM 10365 O  O   . HOH W 8 .   ? -17.574 -37.173 13.902  1.00 54.69  ? 959 HOH A O   1 
HETATM 10366 O  O   . HOH W 8 .   ? -34.086 -27.548 4.849   1.00 51.66  ? 960 HOH A O   1 
HETATM 10367 O  O   . HOH W 8 .   ? -39.589 -23.414 12.413  1.00 43.94  ? 961 HOH A O   1 
HETATM 10368 O  O   . HOH W 8 .   ? 2.245   -18.346 4.659   1.00 61.58  ? 962 HOH A O   1 
HETATM 10369 O  O   . HOH W 8 .   ? -12.247 -37.747 2.298   1.00 47.15  ? 963 HOH A O   1 
HETATM 10370 O  O   . HOH W 8 .   ? -37.114 -25.534 3.187   1.00 50.57  ? 964 HOH A O   1 
HETATM 10371 O  O   . HOH W 8 .   ? -14.465 0.399   21.490  1.00 50.08  ? 965 HOH A O   1 
HETATM 10372 O  O   . HOH W 8 .   ? -33.771 -27.380 27.552  1.00 38.58  ? 966 HOH A O   1 
HETATM 10373 O  O   . HOH W 8 .   ? -19.363 -38.827 6.804   1.00 37.14  ? 967 HOH A O   1 
HETATM 10374 O  O   . HOH W 8 .   ? -43.707 -26.662 16.774  1.00 51.49  ? 968 HOH A O   1 
HETATM 10375 O  O   . HOH W 8 .   ? -25.081 -38.826 4.104   1.00 42.51  ? 969 HOH A O   1 
HETATM 10376 O  O   . HOH W 8 .   ? -19.013 -13.690 -8.194  1.00 51.27  ? 970 HOH A O   1 
HETATM 10377 O  O   . HOH W 8 .   ? -36.759 -24.006 5.243   1.00 44.17  ? 971 HOH A O   1 
HETATM 10378 O  O   . HOH W 8 .   ? -6.853  -3.348  27.610  1.00 47.55  ? 972 HOH A O   1 
HETATM 10379 O  O   . HOH W 8 .   ? -17.170 -43.707 29.678  1.00 42.79  ? 973 HOH A O   1 
HETATM 10380 O  O   . HOH W 8 .   ? -16.851 -33.410 -1.871  1.00 40.73  ? 974 HOH A O   1 
HETATM 10381 O  O   . HOH W 8 .   ? -30.269 -0.567  37.751  1.00 48.48  ? 975 HOH A O   1 
HETATM 10382 O  O   . HOH W 8 .   ? -20.198 -13.037 -6.117  1.00 48.59  ? 976 HOH A O   1 
HETATM 10383 O  O   . HOH W 8 .   ? -17.655 -0.022  18.561  1.00 40.38  ? 977 HOH A O   1 
HETATM 10384 O  O   . HOH W 8 .   ? -9.427  -51.743 15.601  1.00 47.53  ? 978 HOH A O   1 
HETATM 10385 O  O   . HOH W 8 .   ? -42.628 -27.675 14.260  1.00 53.07  ? 979 HOH A O   1 
HETATM 10386 O  O   . HOH W 8 .   ? -21.798 -40.442 6.958   1.00 46.13  ? 980 HOH A O   1 
HETATM 10387 O  O   . HOH W 8 .   ? -22.781 -40.382 4.161   1.00 47.72  ? 981 HOH A O   1 
HETATM 10388 O  O   . HOH X 8 .   ? -70.149 24.442  34.530  1.00 42.92  ? 601 HOH B O   1 
HETATM 10389 O  O   . HOH X 8 .   ? -24.054 24.667  35.188  1.00 53.32  ? 602 HOH B O   1 
HETATM 10390 O  O   . HOH X 8 .   ? -42.850 -18.489 22.424  1.00 44.98  ? 603 HOH B O   1 
HETATM 10391 O  O   . HOH X 8 .   ? -44.479 20.642  16.853  1.00 37.95  ? 604 HOH B O   1 
HETATM 10392 O  O   . HOH X 8 .   ? -56.097 1.450   16.831  1.00 32.99  ? 605 HOH B O   1 
HETATM 10393 O  O   . HOH X 8 .   ? -70.147 10.326  22.122  1.00 48.59  ? 606 HOH B O   1 
HETATM 10394 O  O   . HOH X 8 .   ? -25.209 16.806  54.330  1.00 47.77  ? 607 HOH B O   1 
HETATM 10395 O  O   . HOH X 8 .   ? -55.230 -11.038 7.536   1.00 65.19  ? 608 HOH B O   1 
HETATM 10396 O  O   . HOH X 8 .   ? -40.269 16.962  11.935  1.00 46.71  ? 609 HOH B O   1 
HETATM 10397 O  O   . HOH X 8 .   ? -67.785 10.020  20.748  1.00 39.10  ? 610 HOH B O   1 
HETATM 10398 O  O   . HOH X 8 .   ? -67.353 24.718  27.190  1.00 36.63  ? 611 HOH B O   1 
HETATM 10399 O  O   . HOH X 8 .   ? -51.786 37.728  36.776  1.00 36.50  ? 612 HOH B O   1 
HETATM 10400 O  O   . HOH X 8 .   ? -57.471 10.709  3.457   1.00 42.76  ? 613 HOH B O   1 
HETATM 10401 O  O   . HOH X 8 .   ? -55.871 25.682  20.036  1.00 40.91  ? 614 HOH B O   1 
HETATM 10402 O  O   . HOH X 8 .   ? -33.637 32.097  40.793  1.00 40.51  ? 615 HOH B O   1 
HETATM 10403 O  O   . HOH X 8 .   ? -66.985 27.753  40.887  1.00 44.82  ? 616 HOH B O   1 
HETATM 10404 O  O   . HOH X 8 .   ? -51.179 -8.709  34.619  1.00 53.58  ? 617 HOH B O   1 
HETATM 10405 O  O   . HOH X 8 .   ? -32.769 34.863  35.192  1.00 47.82  ? 618 HOH B O   1 
HETATM 10406 O  O   . HOH X 8 .   ? -51.037 -11.042 31.637  1.00 40.24  ? 619 HOH B O   1 
HETATM 10407 O  O   . HOH X 8 .   ? -62.538 1.447   24.152  1.00 46.32  ? 620 HOH B O   1 
HETATM 10408 O  O   . HOH X 8 .   ? -58.319 -0.247  22.689  1.00 37.77  ? 621 HOH B O   1 
HETATM 10409 O  O   . HOH X 8 .   ? -38.340 36.023  28.348  1.00 35.98  ? 622 HOH B O   1 
HETATM 10410 O  O   . HOH X 8 .   ? -35.346 -5.188  33.052  1.00 33.37  ? 623 HOH B O   1 
HETATM 10411 O  O   . HOH X 8 .   ? -28.395 15.114  14.335  1.00 42.07  ? 624 HOH B O   1 
HETATM 10412 O  O   . HOH X 8 .   ? -68.750 27.604  36.863  1.00 47.26  ? 625 HOH B O   1 
HETATM 10413 O  O   . HOH X 8 .   ? -50.060 -14.189 26.946  1.00 50.63  ? 626 HOH B O   1 
HETATM 10414 O  O   . HOH X 8 .   ? -47.741 31.738  47.577  1.00 39.40  ? 627 HOH B O   1 
HETATM 10415 O  O   . HOH X 8 .   ? -26.142 2.371   41.565  1.00 49.49  ? 628 HOH B O   1 
HETATM 10416 O  O   . HOH X 8 .   ? -34.079 -0.219  42.923  1.00 33.42  ? 629 HOH B O   1 
HETATM 10417 O  O   . HOH X 8 .   ? -54.462 12.296  34.860  1.00 28.16  ? 630 HOH B O   1 
HETATM 10418 O  O   . HOH X 8 .   ? -37.457 2.502   28.232  1.00 30.64  ? 631 HOH B O   1 
HETATM 10419 O  O   . HOH X 8 .   ? -52.890 -4.056  32.840  1.00 38.07  ? 632 HOH B O   1 
HETATM 10420 O  O   . HOH X 8 .   ? -40.885 34.633  20.484  1.00 43.71  ? 633 HOH B O   1 
HETATM 10421 O  O   . HOH X 8 .   ? -70.275 21.741  27.059  1.00 45.86  ? 634 HOH B O   1 
HETATM 10422 O  O   . HOH X 8 .   ? -38.659 18.809  49.778  1.00 32.36  ? 635 HOH B O   1 
HETATM 10423 O  O   . HOH X 8 .   ? -52.044 11.030  39.047  1.00 29.80  ? 636 HOH B O   1 
HETATM 10424 O  O   . HOH X 8 .   ? -40.171 -14.209 29.305  1.00 41.98  ? 637 HOH B O   1 
HETATM 10425 O  O   . HOH X 8 .   ? -38.685 19.675  22.522  1.00 30.28  ? 638 HOH B O   1 
HETATM 10426 O  O   . HOH X 8 .   ? -41.014 37.551  33.858  1.00 35.08  ? 639 HOH B O   1 
HETATM 10427 O  O   . HOH X 8 .   ? -51.073 -5.573  13.754  1.00 38.38  ? 640 HOH B O   1 
HETATM 10428 O  O   . HOH X 8 .   ? -51.081 1.628   44.394  1.00 45.30  ? 641 HOH B O   1 
HETATM 10429 O  O   . HOH X 8 .   ? -42.202 -6.637  42.485  1.00 44.97  ? 642 HOH B O   1 
HETATM 10430 O  O   . HOH X 8 .   ? -65.438 23.705  22.169  1.00 49.12  ? 643 HOH B O   1 
HETATM 10431 O  O   . HOH X 8 .   ? -19.947 20.265  34.016  1.00 43.25  ? 644 HOH B O   1 
HETATM 10432 O  O   . HOH X 8 .   ? -64.580 8.868   36.510  1.00 37.24  ? 645 HOH B O   1 
HETATM 10433 O  O   . HOH X 8 .   ? -41.663 5.638   32.581  1.00 24.46  ? 646 HOH B O   1 
HETATM 10434 O  O   . HOH X 8 .   ? -30.652 -4.705  44.957  1.00 47.20  ? 647 HOH B O   1 
HETATM 10435 O  O   . HOH X 8 .   ? -41.018 -14.124 18.996  1.00 35.88  ? 648 HOH B O   1 
HETATM 10436 O  O   . HOH X 8 .   ? -36.902 32.111  43.695  1.00 43.21  ? 649 HOH B O   1 
HETATM 10437 O  O   . HOH X 8 .   ? -26.932 6.363   35.945  1.00 42.39  ? 650 HOH B O   1 
HETATM 10438 O  O   . HOH X 8 .   ? -39.731 22.100  21.631  1.00 31.24  ? 651 HOH B O   1 
HETATM 10439 O  O   . HOH X 8 .   ? -40.613 11.789  33.150  1.00 35.84  ? 652 HOH B O   1 
HETATM 10440 O  O   . HOH X 8 .   ? -24.184 12.279  31.618  1.00 37.75  ? 653 HOH B O   1 
HETATM 10441 O  O   . HOH X 8 .   ? -32.301 27.434  44.770  1.00 44.09  ? 654 HOH B O   1 
HETATM 10442 O  O   . HOH X 8 .   ? -58.506 -5.331  28.675  1.00 43.59  ? 655 HOH B O   1 
HETATM 10443 O  O   . HOH X 8 .   ? -67.534 16.968  34.628  1.00 39.05  ? 656 HOH B O   1 
HETATM 10444 O  O   . HOH X 8 .   ? -40.527 3.639   30.915  1.00 26.01  ? 657 HOH B O   1 
HETATM 10445 O  O   . HOH X 8 .   ? -51.308 40.337  36.750  1.00 38.22  ? 658 HOH B O   1 
HETATM 10446 O  O   . HOH X 8 .   ? -37.703 21.724  19.257  1.00 40.67  ? 659 HOH B O   1 
HETATM 10447 O  O   . HOH X 8 .   ? -53.852 -9.567  25.306  1.00 45.43  ? 660 HOH B O   1 
HETATM 10448 O  O   . HOH X 8 .   ? -55.118 -0.603  32.909  1.00 43.04  ? 661 HOH B O   1 
HETATM 10449 O  O   . HOH X 8 .   ? -44.224 5.526   47.971  1.00 43.15  ? 662 HOH B O   1 
HETATM 10450 O  O   . HOH X 8 .   ? -52.713 16.653  46.490  1.00 37.08  ? 663 HOH B O   1 
HETATM 10451 O  O   . HOH X 8 .   ? -27.502 3.154   38.630  1.00 42.99  ? 664 HOH B O   1 
HETATM 10452 O  O   . HOH X 8 .   ? -42.301 17.127  8.724   1.00 49.81  ? 665 HOH B O   1 
HETATM 10453 O  O   . HOH X 8 .   ? -49.298 11.360  39.533  1.00 23.95  ? 666 HOH B O   1 
HETATM 10454 O  O   . HOH X 8 .   ? -35.066 -1.818  18.238  1.00 37.30  ? 667 HOH B O   1 
HETATM 10455 O  O   . HOH X 8 .   ? -43.096 -9.969  34.476  1.00 38.00  ? 668 HOH B O   1 
HETATM 10456 O  O   . HOH X 8 .   ? -32.409 16.923  33.508  1.00 27.86  ? 669 HOH B O   1 
HETATM 10457 O  O   . HOH X 8 .   ? -47.431 46.532  27.994  1.00 45.71  ? 670 HOH B O   1 
HETATM 10458 O  O   . HOH X 8 .   ? -38.188 -7.953  25.890  1.00 39.10  ? 671 HOH B O   1 
HETATM 10459 O  O   . HOH X 8 .   ? -40.016 38.355  31.157  1.00 36.30  ? 672 HOH B O   1 
HETATM 10460 O  O   . HOH X 8 .   ? -45.472 -8.508  15.553  1.00 42.87  ? 673 HOH B O   1 
HETATM 10461 O  O   . HOH X 8 .   ? -56.363 10.134  34.686  1.00 35.05  ? 674 HOH B O   1 
HETATM 10462 O  O   . HOH X 8 .   ? -57.536 3.808   5.997   1.00 35.11  ? 675 HOH B O   1 
HETATM 10463 O  O   . HOH X 8 .   ? -45.353 -16.928 25.491  1.00 43.25  ? 676 HOH B O   1 
HETATM 10464 O  O   . HOH X 8 .   ? -27.810 12.441  19.845  1.00 38.43  ? 677 HOH B O   1 
HETATM 10465 O  O   . HOH X 8 .   ? -41.886 -2.469  34.246  1.00 28.80  ? 678 HOH B O   1 
HETATM 10466 O  O   . HOH X 8 .   ? -42.108 -6.570  33.379  1.00 31.16  ? 679 HOH B O   1 
HETATM 10467 O  O   . HOH X 8 .   ? -47.932 20.040  53.699  1.00 39.10  ? 680 HOH B O   1 
HETATM 10468 O  O   . HOH X 8 .   ? -57.846 34.768  37.218  1.00 26.12  ? 681 HOH B O   1 
HETATM 10469 O  O   . HOH X 8 .   ? -35.770 27.434  24.461  1.00 42.03  ? 682 HOH B O   1 
HETATM 10470 O  O   . HOH X 8 .   ? -52.531 21.643  44.715  1.00 34.87  ? 683 HOH B O   1 
HETATM 10471 O  O   . HOH X 8 .   ? -55.791 23.299  18.248  1.00 37.18  ? 684 HOH B O   1 
HETATM 10472 O  O   . HOH X 8 .   ? -31.931 13.626  22.177  1.00 28.60  ? 685 HOH B O   1 
HETATM 10473 O  O   . HOH X 8 .   ? -43.895 41.223  16.452  1.00 29.41  ? 686 HOH B O   1 
HETATM 10474 O  O   . HOH X 8 .   ? -26.692 7.606   24.570  1.00 47.85  ? 687 HOH B O   1 
HETATM 10475 O  O   . HOH X 8 .   ? -29.190 26.658  28.438  1.00 40.68  ? 688 HOH B O   1 
HETATM 10476 O  O   . HOH X 8 .   ? -59.384 33.689  39.237  1.00 45.46  ? 689 HOH B O   1 
HETATM 10477 O  O   . HOH X 8 .   ? -22.011 21.035  35.529  1.00 40.52  ? 690 HOH B O   1 
HETATM 10478 O  O   . HOH X 8 .   ? -33.529 2.346   43.729  1.00 33.86  ? 691 HOH B O   1 
HETATM 10479 O  O   . HOH X 8 .   ? -46.231 42.535  15.340  1.00 38.86  ? 692 HOH B O   1 
HETATM 10480 O  O   . HOH X 8 .   ? -30.468 3.469   31.475  1.00 53.98  ? 693 HOH B O   1 
HETATM 10481 O  O   . HOH X 8 .   ? -27.182 10.093  32.151  1.00 31.37  ? 694 HOH B O   1 
HETATM 10482 O  O   . HOH X 8 .   ? -68.549 30.041  35.986  1.00 42.49  ? 695 HOH B O   1 
HETATM 10483 O  O   . HOH X 8 .   ? -51.588 10.658  15.157  1.00 23.57  ? 696 HOH B O   1 
HETATM 10484 O  O   . HOH X 8 .   ? -46.153 28.957  15.752  1.00 36.45  ? 697 HOH B O   1 
HETATM 10485 O  O   . HOH X 8 .   ? -51.397 16.006  26.376  1.00 21.80  ? 698 HOH B O   1 
HETATM 10486 O  O   . HOH X 8 .   ? -48.588 -1.497  35.585  1.00 27.98  ? 699 HOH B O   1 
HETATM 10487 O  O   . HOH X 8 .   ? -68.469 28.572  29.453  1.00 41.03  ? 700 HOH B O   1 
HETATM 10488 O  O   . HOH X 8 .   ? -34.400 0.040   49.687  1.00 43.61  ? 701 HOH B O   1 
HETATM 10489 O  O   . HOH X 8 .   ? -40.713 19.528  41.376  1.00 25.40  ? 702 HOH B O   1 
HETATM 10490 O  O   . HOH X 8 .   ? -34.153 1.175   29.293  1.00 45.10  ? 703 HOH B O   1 
HETATM 10491 O  O   . HOH X 8 .   ? -43.334 23.795  11.274  1.00 42.25  ? 704 HOH B O   1 
HETATM 10492 O  O   . HOH X 8 .   ? -58.362 7.797   42.446  1.00 45.10  ? 705 HOH B O   1 
HETATM 10493 O  O   . HOH X 8 .   ? -55.440 37.274  23.066  1.00 40.56  ? 706 HOH B O   1 
HETATM 10494 O  O   . HOH X 8 .   ? -45.395 39.181  15.055  1.00 29.15  ? 707 HOH B O   1 
HETATM 10495 O  O   . HOH X 8 .   ? -57.638 25.558  40.771  1.00 41.81  ? 708 HOH B O   1 
HETATM 10496 O  O   . HOH X 8 .   ? -39.548 -1.512  17.402  1.00 27.03  ? 709 HOH B O   1 
HETATM 10497 O  O   . HOH X 8 .   ? -47.849 14.526  41.912  1.00 25.98  ? 710 HOH B O   1 
HETATM 10498 O  O   . HOH X 8 .   ? -30.179 2.656   38.055  1.00 35.34  ? 711 HOH B O   1 
HETATM 10499 O  O   . HOH X 8 .   ? -53.116 -14.531 15.887  1.00 48.52  ? 712 HOH B O   1 
HETATM 10500 O  O   . HOH X 8 .   ? -45.844 -1.205  31.578  1.00 27.07  ? 713 HOH B O   1 
HETATM 10501 O  O   . HOH X 8 .   ? -35.033 21.421  18.319  1.00 45.00  ? 714 HOH B O   1 
HETATM 10502 O  O   . HOH X 8 .   ? -44.121 36.551  44.091  1.00 44.37  ? 715 HOH B O   1 
HETATM 10503 O  O   . HOH X 8 .   ? -52.096 10.657  32.881  1.00 21.78  ? 716 HOH B O   1 
HETATM 10504 O  O   . HOH X 8 .   ? -43.705 1.419   44.172  1.00 37.41  ? 717 HOH B O   1 
HETATM 10505 O  O   . HOH X 8 .   ? -28.644 28.103  31.205  1.00 29.64  ? 718 HOH B O   1 
HETATM 10506 O  O   . HOH X 8 .   ? -57.407 5.378   9.586   1.00 30.98  ? 719 HOH B O   1 
HETATM 10507 O  O   . HOH X 8 .   ? -62.097 29.136  19.811  1.00 33.83  ? 720 HOH B O   1 
HETATM 10508 O  O   . HOH X 8 .   ? -56.177 45.723  31.915  1.00 26.56  ? 721 HOH B O   1 
HETATM 10509 O  O   . HOH X 8 .   ? -62.880 2.015   29.472  1.00 49.72  ? 722 HOH B O   1 
HETATM 10510 O  O   . HOH X 8 .   ? -49.499 46.503  35.701  1.00 38.21  ? 723 HOH B O   1 
HETATM 10511 O  O   . HOH X 8 .   ? -53.979 26.888  18.197  1.00 38.90  ? 724 HOH B O   1 
HETATM 10512 O  O   . HOH X 8 .   ? -59.510 15.533  17.974  1.00 30.56  ? 725 HOH B O   1 
HETATM 10513 O  O   . HOH X 8 .   ? -29.367 22.880  48.673  1.00 41.82  ? 726 HOH B O   1 
HETATM 10514 O  O   . HOH X 8 .   ? -37.166 18.780  20.634  1.00 30.59  ? 727 HOH B O   1 
HETATM 10515 O  O   . HOH X 8 .   ? -23.558 16.813  22.487  1.00 42.52  ? 728 HOH B O   1 
HETATM 10516 O  O   . HOH X 8 .   ? -53.749 10.048  46.142  1.00 35.45  ? 729 HOH B O   1 
HETATM 10517 O  O   . HOH X 8 .   ? -48.976 40.595  23.795  1.00 30.85  ? 730 HOH B O   1 
HETATM 10518 O  O   . HOH X 8 .   ? -46.203 26.577  13.733  1.00 40.89  ? 731 HOH B O   1 
HETATM 10519 O  O   . HOH X 8 .   ? -41.218 22.748  19.263  1.00 43.84  ? 732 HOH B O   1 
HETATM 10520 O  O   . HOH X 8 .   ? -61.522 6.036   18.419  1.00 33.27  ? 733 HOH B O   1 
HETATM 10521 O  O   . HOH X 8 .   ? -41.521 44.871  33.884  1.00 44.09  ? 734 HOH B O   1 
HETATM 10522 O  O   . HOH X 8 .   ? -68.033 20.504  23.574  1.00 43.10  ? 735 HOH B O   1 
HETATM 10523 O  O   . HOH X 8 .   ? -50.858 24.477  50.244  1.00 41.52  ? 736 HOH B O   1 
HETATM 10524 O  O   . HOH X 8 .   ? -52.204 25.784  42.042  1.00 26.49  ? 737 HOH B O   1 
HETATM 10525 O  O   . HOH X 8 .   ? -56.673 -9.267  23.369  1.00 40.56  ? 738 HOH B O   1 
HETATM 10526 O  O   . HOH X 8 .   ? -49.094 -5.498  35.768  1.00 31.49  ? 739 HOH B O   1 
HETATM 10527 O  O   . HOH X 8 .   ? -67.203 31.929  37.479  1.00 35.67  ? 740 HOH B O   1 
HETATM 10528 O  O   . HOH X 8 .   ? -53.763 40.138  21.402  1.00 38.02  ? 741 HOH B O   1 
HETATM 10529 O  O   . HOH X 8 .   ? -47.593 -8.771  14.749  1.00 41.75  ? 742 HOH B O   1 
HETATM 10530 O  O   . HOH X 8 .   ? -64.580 25.856  25.312  1.00 38.40  ? 743 HOH B O   1 
HETATM 10531 O  O   . HOH X 8 .   ? -44.772 24.980  16.335  1.00 31.69  ? 744 HOH B O   1 
HETATM 10532 O  O   . HOH X 8 .   ? -63.086 25.907  22.068  1.00 46.91  ? 745 HOH B O   1 
HETATM 10533 O  O   . HOH X 8 .   ? -47.989 6.371   6.836   1.00 37.87  ? 746 HOH B O   1 
HETATM 10534 O  O   . HOH X 8 .   ? -32.192 30.908  32.657  1.00 35.68  ? 747 HOH B O   1 
HETATM 10535 O  O   . HOH X 8 .   ? -39.314 16.031  16.355  1.00 28.04  ? 748 HOH B O   1 
HETATM 10536 O  O   . HOH X 8 .   ? -40.622 40.169  38.851  1.00 44.37  ? 749 HOH B O   1 
HETATM 10537 O  O   . HOH X 8 .   ? -33.593 4.767   51.228  1.00 40.57  ? 750 HOH B O   1 
HETATM 10538 O  O   . HOH X 8 .   ? -40.236 3.212   28.013  1.00 33.26  ? 751 HOH B O   1 
HETATM 10539 O  O   . HOH X 8 .   ? -55.891 -12.125 21.024  1.00 35.53  ? 752 HOH B O   1 
HETATM 10540 O  O   . HOH X 8 .   ? -50.994 4.219   43.408  1.00 49.70  ? 753 HOH B O   1 
HETATM 10541 O  O   . HOH X 8 .   ? -51.673 31.740  40.323  1.00 29.88  ? 754 HOH B O   1 
HETATM 10542 O  O   . HOH X 8 .   ? -26.445 13.282  38.102  1.00 34.24  ? 755 HOH B O   1 
HETATM 10543 O  O   . HOH X 8 .   ? -23.991 25.088  41.740  1.00 47.01  ? 756 HOH B O   1 
HETATM 10544 O  O   . HOH X 8 .   ? -33.075 -1.619  33.608  1.00 41.08  ? 757 HOH B O   1 
HETATM 10545 O  O   . HOH X 8 .   ? -32.043 6.248   29.730  1.00 36.27  ? 758 HOH B O   1 
HETATM 10546 O  O   . HOH X 8 .   ? -35.661 16.470  13.346  1.00 33.77  ? 759 HOH B O   1 
HETATM 10547 O  O   . HOH X 8 .   ? -42.600 -2.523  38.790  1.00 38.19  ? 760 HOH B O   1 
HETATM 10548 O  O   . HOH X 8 .   ? -48.823 2.595   35.756  1.00 23.22  ? 761 HOH B O   1 
HETATM 10549 O  O   . HOH X 8 .   ? -32.624 12.967  34.869  1.00 25.98  ? 762 HOH B O   1 
HETATM 10550 O  O   . HOH X 8 .   ? -41.439 18.097  49.916  1.00 44.58  ? 763 HOH B O   1 
HETATM 10551 O  O   . HOH X 8 .   ? -45.763 19.527  23.813  1.00 29.82  ? 764 HOH B O   1 
HETATM 10552 O  O   . HOH X 8 .   ? -53.653 33.785  40.840  1.00 52.63  ? 765 HOH B O   1 
HETATM 10553 O  O   . HOH X 8 .   ? -68.041 12.243  19.671  1.00 40.89  ? 766 HOH B O   1 
HETATM 10554 O  O   . HOH X 8 .   ? -37.883 8.757   49.151  1.00 34.16  ? 767 HOH B O   1 
HETATM 10555 O  O   . HOH X 8 .   ? -49.431 14.181  26.979  1.00 23.38  ? 768 HOH B O   1 
HETATM 10556 O  O   . HOH X 8 .   ? -46.117 -0.399  34.155  1.00 17.64  ? 769 HOH B O   1 
HETATM 10557 O  O   . HOH X 8 .   ? -35.264 7.800   49.172  1.00 33.21  ? 770 HOH B O   1 
HETATM 10558 O  O   . HOH X 8 .   ? -52.180 18.408  48.325  1.00 30.59  ? 771 HOH B O   1 
HETATM 10559 O  O   . HOH X 8 .   ? -35.545 8.054   52.029  1.00 45.50  ? 772 HOH B O   1 
HETATM 10560 O  O   . HOH X 8 .   ? -39.823 33.538  35.607  1.00 42.42  ? 773 HOH B O   1 
HETATM 10561 O  O   . HOH X 8 .   ? -26.791 23.579  24.284  1.00 38.89  ? 774 HOH B O   1 
HETATM 10562 O  O   . HOH X 8 .   ? -27.205 10.379  29.570  1.00 38.59  ? 775 HOH B O   1 
HETATM 10563 O  O   . HOH X 8 .   ? -36.366 31.097  30.575  1.00 37.18  ? 776 HOH B O   1 
HETATM 10564 O  O   . HOH X 8 .   ? -40.324 33.236  38.831  1.00 29.69  ? 777 HOH B O   1 
HETATM 10565 O  O   . HOH X 8 .   ? -27.881 16.952  54.767  1.00 40.07  ? 778 HOH B O   1 
HETATM 10566 O  O   . HOH X 8 .   ? -40.753 21.777  50.254  1.00 43.20  ? 779 HOH B O   1 
HETATM 10567 O  O   . HOH X 8 .   ? -41.845 -4.752  35.683  1.00 30.44  ? 780 HOH B O   1 
HETATM 10568 O  O   . HOH X 8 .   ? -50.449 14.277  23.936  1.00 23.24  ? 781 HOH B O   1 
HETATM 10569 O  O   . HOH X 8 .   ? -62.859 21.524  38.927  1.00 40.03  ? 782 HOH B O   1 
HETATM 10570 O  O   . HOH X 8 .   ? -42.250 -16.421 24.503  1.00 37.56  ? 783 HOH B O   1 
HETATM 10571 O  O   . HOH X 8 .   ? -48.833 41.568  37.062  1.00 49.42  ? 784 HOH B O   1 
HETATM 10572 O  O   . HOH X 8 .   ? -56.587 6.981   34.555  1.00 36.97  ? 785 HOH B O   1 
HETATM 10573 O  O   . HOH X 8 .   ? -21.894 8.212   47.064  1.00 43.47  ? 786 HOH B O   1 
HETATM 10574 O  O   . HOH X 8 .   ? -63.148 5.641   32.758  1.00 28.27  ? 787 HOH B O   1 
HETATM 10575 O  O   . HOH X 8 .   ? -43.557 -2.763  32.074  1.00 28.07  ? 788 HOH B O   1 
HETATM 10576 O  O   . HOH X 8 .   ? -51.226 11.437  49.317  1.00 43.53  ? 789 HOH B O   1 
HETATM 10577 O  O   . HOH X 8 .   ? -69.163 17.255  24.109  1.00 51.77  ? 790 HOH B O   1 
HETATM 10578 O  O   . HOH X 8 .   ? -56.340 -5.501  26.865  1.00 35.11  ? 791 HOH B O   1 
HETATM 10579 O  O   . HOH X 8 .   ? -23.156 20.758  42.370  1.00 31.03  ? 792 HOH B O   1 
HETATM 10580 O  O   . HOH X 8 .   ? -39.508 37.975  26.337  1.00 43.87  ? 793 HOH B O   1 
HETATM 10581 O  O   . HOH X 8 .   ? -49.806 33.258  41.354  1.00 34.83  ? 794 HOH B O   1 
HETATM 10582 O  O   . HOH X 8 .   ? -63.887 9.612   29.000  1.00 46.54  ? 795 HOH B O   1 
HETATM 10583 O  O   . HOH X 8 .   ? -62.373 -0.887  16.199  1.00 42.34  ? 796 HOH B O   1 
HETATM 10584 O  O   . HOH X 8 .   ? -53.292 11.852  4.981   1.00 42.31  ? 797 HOH B O   1 
HETATM 10585 O  O   . HOH X 8 .   ? -36.812 4.596   8.253   1.00 46.33  ? 798 HOH B O   1 
HETATM 10586 O  O   . HOH X 8 .   ? -55.874 4.696   33.017  1.00 31.88  ? 799 HOH B O   1 
HETATM 10587 O  O   . HOH X 8 .   ? -70.292 13.766  17.824  1.00 51.77  ? 800 HOH B O   1 
HETATM 10588 O  O   . HOH X 8 .   ? -52.555 5.714   40.884  1.00 39.12  ? 801 HOH B O   1 
HETATM 10589 O  O   . HOH X 8 .   ? -40.212 23.810  29.601  1.00 32.19  ? 802 HOH B O   1 
HETATM 10590 O  O   . HOH X 8 .   ? -32.160 22.256  51.943  1.00 53.83  ? 803 HOH B O   1 
HETATM 10591 O  O   . HOH X 8 .   ? -32.811 28.277  28.493  1.00 31.07  ? 804 HOH B O   1 
HETATM 10592 O  O   . HOH X 8 .   ? -52.561 25.406  13.121  1.00 45.57  ? 805 HOH B O   1 
HETATM 10593 O  O   . HOH X 8 .   ? -48.593 10.830  18.511  1.00 33.85  ? 806 HOH B O   1 
HETATM 10594 O  O   . HOH X 8 .   ? -58.825 26.050  22.496  1.00 32.94  ? 807 HOH B O   1 
HETATM 10595 O  O   . HOH X 8 .   ? -62.450 37.162  28.577  1.00 34.06  ? 808 HOH B O   1 
HETATM 10596 O  O   . HOH X 8 .   ? -55.350 -0.022  19.263  1.00 33.95  ? 809 HOH B O   1 
HETATM 10597 O  O   . HOH X 8 .   ? -60.079 13.153  46.105  1.00 47.81  ? 810 HOH B O   1 
HETATM 10598 O  O   . HOH X 8 .   ? -34.156 19.034  13.257  1.00 42.89  ? 811 HOH B O   1 
HETATM 10599 O  O   . HOH X 8 .   ? -48.155 -3.217  37.546  1.00 39.50  ? 812 HOH B O   1 
HETATM 10600 O  O   . HOH X 8 .   ? -43.858 49.850  27.996  1.00 50.62  ? 813 HOH B O   1 
HETATM 10601 O  O   . HOH X 8 .   ? -59.085 35.894  25.929  1.00 26.74  ? 814 HOH B O   1 
HETATM 10602 O  O   . HOH X 8 .   ? -21.342 7.289   44.360  1.00 46.01  ? 815 HOH B O   1 
HETATM 10603 O  O   . HOH X 8 .   ? -41.302 10.179  5.896   1.00 49.95  ? 816 HOH B O   1 
HETATM 10604 O  O   . HOH X 8 .   ? -39.008 28.272  18.069  1.00 54.91  ? 817 HOH B O   1 
HETATM 10605 O  O   . HOH X 8 .   ? -43.883 25.473  51.192  1.00 35.92  ? 818 HOH B O   1 
HETATM 10606 O  O   . HOH X 8 .   ? -51.495 7.857   5.750   1.00 43.41  ? 819 HOH B O   1 
HETATM 10607 O  O   . HOH X 8 .   ? -53.406 2.148   17.060  1.00 29.53  ? 820 HOH B O   1 
HETATM 10608 O  O   . HOH X 8 .   ? -61.572 28.981  38.788  1.00 30.56  ? 821 HOH B O   1 
HETATM 10609 O  O   . HOH X 8 .   ? -50.775 27.378  43.625  1.00 32.72  ? 822 HOH B O   1 
HETATM 10610 O  O   . HOH X 8 .   ? -46.341 20.672  10.457  1.00 39.02  ? 823 HOH B O   1 
HETATM 10611 O  O   . HOH X 8 .   ? -72.506 16.199  20.120  1.00 45.66  ? 824 HOH B O   1 
HETATM 10612 O  O   . HOH X 8 .   ? -39.399 44.348  27.131  1.00 43.67  ? 825 HOH B O   1 
HETATM 10613 O  O   . HOH X 8 .   ? -54.401 19.350  19.405  1.00 53.19  ? 826 HOH B O   1 
HETATM 10614 O  O   . HOH X 8 .   ? -64.108 6.095   28.033  1.00 42.15  ? 827 HOH B O   1 
HETATM 10615 O  O   . HOH X 8 .   ? -45.094 -3.459  40.715  1.00 44.98  ? 828 HOH B O   1 
HETATM 10616 O  O   . HOH X 8 .   ? -24.558 22.856  43.359  1.00 39.39  ? 829 HOH B O   1 
HETATM 10617 O  O   . HOH X 8 .   ? -57.868 29.020  43.539  1.00 56.06  ? 830 HOH B O   1 
HETATM 10618 O  O   . HOH X 8 .   ? -65.148 15.712  17.950  1.00 35.26  ? 831 HOH B O   1 
HETATM 10619 O  O   . HOH X 8 .   ? -22.256 25.092  28.657  1.00 48.54  ? 832 HOH B O   1 
HETATM 10620 O  O   . HOH X 8 .   ? -40.463 40.757  30.560  1.00 48.12  ? 833 HOH B O   1 
HETATM 10621 O  O   . HOH X 8 .   ? -29.475 34.453  45.763  1.00 51.60  ? 834 HOH B O   1 
HETATM 10622 O  O   . HOH X 8 .   ? -34.656 -3.484  35.792  1.00 31.14  ? 835 HOH B O   1 
HETATM 10623 O  O   . HOH X 8 .   ? -55.430 38.676  25.738  1.00 24.74  ? 836 HOH B O   1 
HETATM 10624 O  O   . HOH X 8 .   ? -53.045 34.992  13.620  1.00 31.76  ? 837 HOH B O   1 
HETATM 10625 O  O   . HOH X 8 .   ? -52.880 9.528   17.157  1.00 37.19  ? 838 HOH B O   1 
HETATM 10626 O  O   . HOH X 8 .   ? -48.734 20.504  11.715  1.00 32.45  ? 839 HOH B O   1 
HETATM 10627 O  O   . HOH X 8 .   ? -54.537 41.335  39.519  1.00 49.75  ? 840 HOH B O   1 
HETATM 10628 O  O   . HOH X 8 .   ? -19.657 15.509  39.095  1.00 50.35  ? 841 HOH B O   1 
HETATM 10629 O  O   . HOH X 8 .   ? -52.116 24.932  15.480  1.00 36.53  ? 842 HOH B O   1 
HETATM 10630 O  O   . HOH X 8 .   ? -53.745 32.256  12.982  1.00 33.56  ? 843 HOH B O   1 
HETATM 10631 O  O   . HOH X 8 .   ? -49.925 49.534  36.432  1.00 49.13  ? 844 HOH B O   1 
HETATM 10632 O  O   . HOH X 8 .   ? -31.554 0.123   41.463  1.00 46.17  ? 845 HOH B O   1 
HETATM 10633 O  O   . HOH X 8 .   ? -32.580 26.270  22.133  1.00 39.26  ? 846 HOH B O   1 
HETATM 10634 O  O   . HOH X 8 .   ? -47.709 -0.732  3.565   1.00 44.29  ? 847 HOH B O   1 
HETATM 10635 O  O   . HOH X 8 .   ? -60.261 31.023  39.536  1.00 35.62  ? 848 HOH B O   1 
HETATM 10636 O  O   . HOH X 8 .   ? -24.645 9.257   33.262  1.00 36.92  ? 849 HOH B O   1 
HETATM 10637 O  O   . HOH X 8 .   ? -41.116 14.527  15.132  1.00 32.37  ? 850 HOH B O   1 
HETATM 10638 O  O   . HOH X 8 .   ? -55.495 14.839  44.297  1.00 30.78  ? 851 HOH B O   1 
HETATM 10639 O  O   . HOH X 8 .   ? -48.308 34.193  45.560  1.00 52.38  ? 852 HOH B O   1 
HETATM 10640 O  O   . HOH X 8 .   ? -41.700 25.062  18.188  1.00 45.45  ? 853 HOH B O   1 
HETATM 10641 O  O   . HOH X 8 .   ? -48.430 48.784  29.233  1.00 42.64  ? 854 HOH B O   1 
HETATM 10642 O  O   . HOH X 8 .   ? -21.521 8.068   41.008  1.00 41.74  ? 855 HOH B O   1 
HETATM 10643 O  O   . HOH X 8 .   ? -23.850 25.016  38.617  1.00 51.89  ? 856 HOH B O   1 
HETATM 10644 O  O   . HOH X 8 .   ? -43.266 -6.607  37.803  1.00 40.11  ? 857 HOH B O   1 
HETATM 10645 O  O   . HOH X 8 .   ? -51.698 -4.480  35.299  1.00 49.35  ? 858 HOH B O   1 
HETATM 10646 O  O   . HOH X 8 .   ? -50.410 -0.285  37.369  1.00 28.25  ? 859 HOH B O   1 
HETATM 10647 O  O   . HOH X 8 .   ? -30.922 5.383   19.941  1.00 34.61  ? 860 HOH B O   1 
HETATM 10648 O  O   . HOH X 8 .   ? -66.297 13.283  27.711  1.00 26.00  ? 861 HOH B O   1 
HETATM 10649 O  O   . HOH X 8 .   ? -40.451 36.761  23.438  1.00 29.67  ? 862 HOH B O   1 
HETATM 10650 O  O   . HOH X 8 .   ? -17.923 15.975  31.429  1.00 39.90  ? 863 HOH B O   1 
HETATM 10651 O  O   . HOH X 8 .   ? -60.530 -0.205  23.869  1.00 41.13  ? 864 HOH B O   1 
HETATM 10652 O  O   . HOH X 8 .   ? -34.237 28.383  26.439  1.00 49.38  ? 865 HOH B O   1 
HETATM 10653 O  O   . HOH X 8 .   ? -61.116 -0.573  10.862  1.00 37.90  ? 866 HOH B O   1 
HETATM 10654 O  O   . HOH X 8 .   ? -27.132 23.571  47.861  1.00 56.83  ? 867 HOH B O   1 
HETATM 10655 O  O   . HOH X 8 .   ? -65.123 30.329  25.633  1.00 21.96  ? 868 HOH B O   1 
HETATM 10656 O  O   . HOH X 8 .   ? -61.726 38.452  31.167  1.00 28.91  ? 869 HOH B O   1 
HETATM 10657 O  O   . HOH X 8 .   ? -21.562 30.553  35.423  1.00 60.57  ? 870 HOH B O   1 
HETATM 10658 O  O   . HOH X 8 .   ? -53.517 15.322  23.063  1.00 34.87  ? 871 HOH B O   1 
HETATM 10659 O  O   . HOH X 8 .   ? -38.883 12.083  35.250  1.00 39.46  ? 872 HOH B O   1 
HETATM 10660 O  O   . HOH X 8 .   ? -42.917 -4.882  40.229  1.00 47.30  ? 873 HOH B O   1 
HETATM 10661 O  O   . HOH X 8 .   ? -34.669 24.130  51.877  1.00 38.91  ? 874 HOH B O   1 
HETATM 10662 O  O   . HOH X 8 .   ? -51.074 37.078  12.271  1.00 21.59  ? 875 HOH B O   1 
HETATM 10663 O  O   . HOH X 8 .   ? -69.480 25.811  28.773  1.00 51.25  ? 876 HOH B O   1 
HETATM 10664 O  O   . HOH X 8 .   ? -53.411 16.639  20.083  1.00 34.88  ? 877 HOH B O   1 
HETATM 10665 O  O   . HOH X 8 .   ? -56.100 2.137   33.701  1.00 38.00  ? 878 HOH B O   1 
HETATM 10666 O  O   . HOH X 8 .   ? -29.289 37.858  40.701  1.00 57.20  ? 879 HOH B O   1 
HETATM 10667 O  O   . HOH X 8 .   ? -33.903 -6.412  29.713  1.00 45.79  ? 880 HOH B O   1 
HETATM 10668 O  O   . HOH X 8 .   ? -68.131 8.090   24.505  1.00 54.49  ? 881 HOH B O   1 
HETATM 10669 O  O   . HOH X 8 .   ? -59.460 4.225   35.609  1.00 52.51  ? 882 HOH B O   1 
HETATM 10670 O  O   . HOH X 8 .   ? -67.621 30.847  41.797  1.00 38.47  ? 883 HOH B O   1 
HETATM 10671 O  O   . HOH X 8 .   ? -71.747 16.859  17.443  1.00 41.61  ? 884 HOH B O   1 
HETATM 10672 O  O   . HOH X 8 .   ? -33.171 1.161   20.273  1.00 44.48  ? 885 HOH B O   1 
HETATM 10673 O  O   . HOH X 8 .   ? -43.275 22.733  17.691  1.00 43.49  ? 886 HOH B O   1 
HETATM 10674 O  O   . HOH X 8 .   ? -46.494 41.319  23.974  1.00 42.51  ? 887 HOH B O   1 
HETATM 10675 O  O   . HOH X 8 .   ? -40.239 5.072   49.912  1.00 45.93  ? 888 HOH B O   1 
HETATM 10676 O  O   . HOH X 8 .   ? -68.798 33.931  35.212  1.00 46.29  ? 889 HOH B O   1 
HETATM 10677 O  O   . HOH X 8 .   ? -59.929 24.027  43.185  1.00 52.08  ? 890 HOH B O   1 
HETATM 10678 O  O   . HOH X 8 .   ? -49.214 -8.025  12.787  1.00 43.51  ? 891 HOH B O   1 
HETATM 10679 O  O   . HOH X 8 .   ? -39.205 30.833  22.774  1.00 43.66  ? 892 HOH B O   1 
HETATM 10680 O  O   . HOH X 8 .   ? -64.774 7.473   34.144  1.00 43.22  ? 893 HOH B O   1 
HETATM 10681 O  O   . HOH X 8 .   ? -54.228 27.768  41.271  1.00 37.21  ? 894 HOH B O   1 
HETATM 10682 O  O   . HOH X 8 .   ? -58.079 17.856  17.864  1.00 42.08  ? 895 HOH B O   1 
HETATM 10683 O  O   . HOH X 8 .   ? -69.912 36.342  38.981  1.00 49.83  ? 896 HOH B O   1 
HETATM 10684 O  O   . HOH X 8 .   ? -38.307 16.909  13.915  1.00 32.93  ? 897 HOH B O   1 
HETATM 10685 O  O   . HOH X 8 .   ? -52.809 30.252  41.901  1.00 43.40  ? 898 HOH B O   1 
HETATM 10686 O  O   . HOH X 8 .   ? -52.105 21.059  47.486  1.00 35.22  ? 899 HOH B O   1 
HETATM 10687 O  O   . HOH X 8 .   ? -52.093 17.631  52.502  1.00 45.84  ? 900 HOH B O   1 
HETATM 10688 O  O   . HOH X 8 .   ? -58.348 26.483  16.952  1.00 55.80  ? 901 HOH B O   1 
HETATM 10689 O  O   . HOH X 8 .   ? -27.748 8.118   22.352  1.00 43.43  ? 902 HOH B O   1 
HETATM 10690 O  O   . HOH X 8 .   ? -26.964 11.523  53.594  1.00 54.43  ? 903 HOH B O   1 
HETATM 10691 O  O   . HOH X 8 .   ? -24.771 11.799  28.476  1.00 47.38  ? 904 HOH B O   1 
HETATM 10692 O  O   . HOH X 8 .   ? -45.675 53.550  34.785  1.00 50.04  ? 905 HOH B O   1 
HETATM 10693 O  O   . HOH X 8 .   ? -67.401 28.344  26.001  1.00 42.77  ? 906 HOH B O   1 
HETATM 10694 O  O   . HOH X 8 .   ? -32.287 5.015   53.574  1.00 55.53  ? 907 HOH B O   1 
HETATM 10695 O  O   . HOH X 8 .   ? -40.679 35.928  44.507  1.00 55.39  ? 908 HOH B O   1 
HETATM 10696 O  O   . HOH X 8 .   ? -30.150 12.109  58.297  1.00 61.17  ? 909 HOH B O   1 
HETATM 10697 O  O   . HOH X 8 .   ? -40.978 10.561  30.640  1.00 42.91  ? 910 HOH B O   1 
HETATM 10698 O  O   . HOH X 8 .   ? -25.600 13.024  55.681  1.00 55.95  ? 911 HOH B O   1 
HETATM 10699 O  O   . HOH X 8 .   ? -40.558 42.796  38.027  1.00 48.85  ? 912 HOH B O   1 
HETATM 10700 O  O   . HOH X 8 .   ? -67.012 26.271  25.179  1.00 44.76  ? 913 HOH B O   1 
HETATM 10701 O  O   . HOH X 8 .   ? -58.801 47.368  28.132  1.00 60.57  ? 914 HOH B O   1 
HETATM 10702 O  O   . HOH X 8 .   ? -39.045 7.711   51.125  1.00 41.70  ? 915 HOH B O   1 
HETATM 10703 O  O   . HOH X 8 .   ? -22.066 15.936  25.228  1.00 43.10  ? 916 HOH B O   1 
HETATM 10704 O  O   . HOH X 8 .   ? -28.054 6.080   20.595  1.00 44.26  ? 917 HOH B O   1 
HETATM 10705 O  O   . HOH X 8 .   ? -44.292 15.165  54.265  1.00 43.75  ? 918 HOH B O   1 
HETATM 10706 O  O   . HOH X 8 .   ? -53.603 18.383  50.733  1.00 40.70  ? 919 HOH B O   1 
HETATM 10707 O  O   . HOH X 8 .   ? -36.439 3.981   51.762  1.00 53.38  ? 920 HOH B O   1 
HETATM 10708 O  O   . HOH X 8 .   ? -51.730 -15.683 24.760  1.00 64.51  ? 921 HOH B O   1 
HETATM 10709 O  O   . HOH X 8 .   ? -39.169 35.696  34.857  1.00 47.51  ? 922 HOH B O   1 
HETATM 10710 O  O   . HOH X 8 .   ? -70.773 23.041  37.065  1.00 46.54  ? 923 HOH B O   1 
HETATM 10711 O  O   . HOH X 8 .   ? -37.347 38.019  31.520  1.00 43.98  ? 924 HOH B O   1 
HETATM 10712 O  O   . HOH X 8 .   ? -32.589 -8.108  17.243  1.00 51.90  ? 925 HOH B O   1 
HETATM 10713 O  O   . HOH X 8 .   ? -53.464 24.028  43.796  1.00 46.54  ? 926 HOH B O   1 
HETATM 10714 O  O   . HOH X 8 .   ? -46.111 50.356  29.469  1.00 45.30  ? 927 HOH B O   1 
HETATM 10715 O  O   . HOH X 8 .   ? -27.971 33.116  47.905  1.00 40.53  ? 928 HOH B O   1 
HETATM 10716 O  O   . HOH X 8 .   ? -50.843 33.824  43.943  1.00 43.89  ? 929 HOH B O   1 
HETATM 10717 O  O   . HOH X 8 .   ? -51.225 27.204  49.844  1.00 47.92  ? 930 HOH B O   1 
HETATM 10718 O  O   . HOH X 8 .   ? -44.717 0.633   46.376  1.00 45.77  ? 931 HOH B O   1 
HETATM 10719 O  O   . HOH X 8 .   ? -41.206 24.291  51.241  1.00 48.39  ? 932 HOH B O   1 
HETATM 10720 O  O   . HOH X 8 .   ? -56.511 39.391  21.448  1.00 44.40  ? 933 HOH B O   1 
HETATM 10721 O  O   . HOH X 8 .   ? -29.807 30.404  31.033  1.00 55.08  ? 934 HOH B O   1 
HETATM 10722 O  O   . HOH X 8 .   ? -34.593 -8.806  14.715  1.00 45.60  ? 935 HOH B O   1 
HETATM 10723 O  O   . HOH X 8 .   ? -33.766 30.061  30.520  1.00 39.97  ? 936 HOH B O   1 
HETATM 10724 O  O   . HOH X 8 .   ? -53.921 -2.364  34.444  1.00 49.32  ? 937 HOH B O   1 
HETATM 10725 O  O   . HOH X 8 .   ? -24.793 7.170   34.917  1.00 41.72  ? 938 HOH B O   1 
HETATM 10726 O  O   . HOH X 8 .   ? -52.719 23.023  49.254  1.00 43.90  ? 939 HOH B O   1 
HETATM 10727 O  O   . HOH X 8 .   ? -40.766 8.770   52.676  1.00 51.49  ? 940 HOH B O   1 
HETATM 10728 O  O   . HOH X 8 .   ? -34.774 30.959  42.911  1.00 43.35  ? 941 HOH B O   1 
HETATM 10729 O  O   . HOH X 8 .   ? -52.470 -1.927  36.917  1.00 47.84  ? 942 HOH B O   1 
HETATM 10730 O  O   . HOH X 8 .   ? -37.488 7.163   28.716  1.00 43.48  ? 943 HOH B O   1 
HETATM 10731 O  O   . HOH X 8 .   ? -23.698 14.326  21.926  1.00 47.26  ? 944 HOH B O   1 
HETATM 10732 O  O   . HOH X 8 .   ? -51.081 19.262  53.955  1.00 52.36  ? 945 HOH B O   1 
HETATM 10733 O  O   . HOH X 8 .   ? -68.417 33.241  47.163  1.00 46.40  ? 946 HOH B O   1 
HETATM 10734 O  O   . HOH X 8 .   ? -59.002 46.807  25.048  1.00 55.32  ? 947 HOH B O   1 
HETATM 10735 O  O   . HOH X 8 .   ? -31.890 2.604   18.997  1.00 50.48  ? 948 HOH B O   1 
HETATM 10736 O  O   . HOH X 8 .   ? -43.817 28.170  51.436  1.00 49.31  ? 949 HOH B O   1 
HETATM 10737 O  O   . HOH X 8 .   ? -24.435 23.291  46.008  1.00 50.31  ? 950 HOH B O   1 
HETATM 10738 O  O   . HOH X 8 .   ? -26.439 10.396  21.291  1.00 40.32  ? 951 HOH B O   1 
HETATM 10739 O  O   . HOH X 8 .   ? -52.231 21.750  53.726  1.00 54.93  ? 952 HOH B O   1 
HETATM 10740 O  O   . HOH Y 8 .   ? -58.372 -12.867 20.996  1.00 49.82  ? 601 HOH C O   1 
HETATM 10741 O  O   . HOH Y 8 .   ? -74.931 -37.346 -18.431 1.00 37.68  ? 602 HOH C O   1 
HETATM 10742 O  O   . HOH Y 8 .   ? -47.987 -45.756 -10.916 1.00 35.86  ? 603 HOH C O   1 
HETATM 10743 O  O   . HOH Y 8 .   ? -79.738 -31.259 -16.684 1.00 46.15  ? 604 HOH C O   1 
HETATM 10744 O  O   . HOH Y 8 .   ? -42.872 -24.655 -3.781  1.00 44.35  ? 605 HOH C O   1 
HETATM 10745 O  O   . HOH Y 8 .   ? -64.438 -30.585 -20.923 1.00 40.48  ? 606 HOH C O   1 
HETATM 10746 O  O   . HOH Y 8 .   ? -61.624 -49.972 -10.230 1.00 43.56  ? 607 HOH C O   1 
HETATM 10747 O  O   . HOH Y 8 .   ? -58.480 -28.561 30.905  1.00 49.87  ? 608 HOH C O   1 
HETATM 10748 O  O   . HOH Y 8 .   ? -49.979 -40.713 10.408  1.00 33.00  ? 609 HOH C O   1 
HETATM 10749 O  O   . HOH Y 8 .   ? -68.335 -40.474 1.714   1.00 31.52  ? 610 HOH C O   1 
HETATM 10750 O  O   . HOH Y 8 .   ? -59.561 -24.511 -14.355 1.00 36.78  ? 611 HOH C O   1 
HETATM 10751 O  O   . HOH Y 8 .   ? -82.069 -32.177 -13.129 1.00 37.42  ? 612 HOH C O   1 
HETATM 10752 O  O   . HOH Y 8 .   ? -59.990 -44.970 21.215  1.00 38.37  ? 613 HOH C O   1 
HETATM 10753 O  O   . HOH Y 8 .   ? -46.876 -27.085 8.953   1.00 36.22  ? 614 HOH C O   1 
HETATM 10754 O  O   . HOH Y 8 .   ? -74.633 -26.043 22.475  1.00 41.06  ? 615 HOH C O   1 
HETATM 10755 O  O   . HOH Y 8 .   ? -71.981 -29.055 30.967  1.00 47.06  ? 616 HOH C O   1 
HETATM 10756 O  O   . HOH Y 8 .   ? -68.635 -39.298 21.759  1.00 38.31  ? 617 HOH C O   1 
HETATM 10757 O  O   . HOH Y 8 .   ? -51.922 -30.497 19.168  1.00 34.50  ? 618 HOH C O   1 
HETATM 10758 O  O   . HOH Y 8 .   ? -69.683 -35.134 -21.899 1.00 50.01  ? 619 HOH C O   1 
HETATM 10759 O  O   . HOH Y 8 .   ? -76.903 -34.489 -18.532 1.00 44.73  ? 620 HOH C O   1 
HETATM 10760 O  O   . HOH Y 8 .   ? -50.542 -36.560 12.109  1.00 43.84  ? 621 HOH C O   1 
HETATM 10761 O  O   . HOH Y 8 .   ? -80.200 -27.159 11.378  1.00 35.65  ? 622 HOH C O   1 
HETATM 10762 O  O   . HOH Y 8 .   ? -50.340 -23.960 -5.211  1.00 40.87  ? 623 HOH C O   1 
HETATM 10763 O  O   . HOH Y 8 .   ? -53.305 -17.215 -9.037  1.00 42.57  ? 624 HOH C O   1 
HETATM 10764 O  O   . HOH Y 8 .   ? -62.070 -24.119 31.136  1.00 47.51  ? 625 HOH C O   1 
HETATM 10765 O  O   . HOH Y 8 .   ? -45.536 -34.982 17.740  1.00 50.54  ? 626 HOH C O   1 
HETATM 10766 O  O   . HOH Y 8 .   ? -78.038 -21.132 -9.009  1.00 28.86  ? 627 HOH C O   1 
HETATM 10767 O  O   . HOH Y 8 .   ? -56.074 -7.590  -10.986 1.00 28.44  ? 628 HOH C O   1 
HETATM 10768 O  O   . HOH Y 8 .   ? -69.919 -31.310 -20.005 1.00 38.54  ? 629 HOH C O   1 
HETATM 10769 O  O   . HOH Y 8 .   ? -81.161 -26.918 -15.957 1.00 35.99  ? 630 HOH C O   1 
HETATM 10770 O  O   . HOH Y 8 .   ? -58.988 -34.278 8.036   1.00 41.59  ? 631 HOH C O   1 
HETATM 10771 O  O   . HOH Y 8 .   ? -62.421 -13.978 10.732  1.00 42.09  ? 632 HOH C O   1 
HETATM 10772 O  O   . HOH Y 8 .   ? -70.163 -15.332 13.420  1.00 38.88  ? 633 HOH C O   1 
HETATM 10773 O  O   . HOH Y 8 .   ? -50.792 -35.500 14.542  1.00 45.10  ? 634 HOH C O   1 
HETATM 10774 O  O   . HOH Y 8 .   ? -50.251 -37.412 17.358  1.00 50.78  ? 635 HOH C O   1 
HETATM 10775 O  O   . HOH Y 8 .   ? -57.958 -53.045 0.991   1.00 42.30  ? 636 HOH C O   1 
HETATM 10776 O  O   . HOH Y 8 .   ? -55.062 -47.900 10.719  1.00 32.17  ? 637 HOH C O   1 
HETATM 10777 O  O   . HOH Y 8 .   ? -59.719 -16.257 19.418  1.00 51.37  ? 638 HOH C O   1 
HETATM 10778 O  O   . HOH Y 8 .   ? -63.098 -39.445 -1.316  1.00 23.86  ? 639 HOH C O   1 
HETATM 10779 O  O   . HOH Y 8 .   ? -70.131 -36.421 6.078   1.00 28.46  ? 640 HOH C O   1 
HETATM 10780 O  O   . HOH Y 8 .   ? -35.334 -36.671 -13.892 1.00 55.56  ? 641 HOH C O   1 
HETATM 10781 O  O   . HOH Y 8 .   ? -78.786 -42.686 -9.626  1.00 32.56  ? 642 HOH C O   1 
HETATM 10782 O  O   . HOH Y 8 .   ? -51.615 -21.808 -2.401  1.00 49.34  ? 643 HOH C O   1 
HETATM 10783 O  O   . HOH Y 8 .   ? -66.067 -41.989 -3.766  1.00 35.81  ? 644 HOH C O   1 
HETATM 10784 O  O   . HOH Y 8 .   ? -53.200 -44.048 -15.649 1.00 39.07  ? 645 HOH C O   1 
HETATM 10785 O  O   . HOH Y 8 .   ? -38.383 -31.141 -9.665  1.00 52.31  ? 646 HOH C O   1 
HETATM 10786 O  O   . HOH Y 8 .   ? -55.567 -34.701 -16.153 1.00 31.72  ? 647 HOH C O   1 
HETATM 10787 O  O   . HOH Y 8 .   ? -70.430 -46.688 -9.583  1.00 26.20  ? 648 HOH C O   1 
HETATM 10788 O  O   . HOH Y 8 .   ? -39.066 -50.793 -0.949  1.00 53.05  ? 649 HOH C O   1 
HETATM 10789 O  O   . HOH Y 8 .   ? -65.494 -35.071 -21.249 1.00 36.47  ? 650 HOH C O   1 
HETATM 10790 O  O   . HOH Y 8 .   ? -77.109 -32.636 1.906   1.00 34.81  ? 651 HOH C O   1 
HETATM 10791 O  O   . HOH Y 8 .   ? -78.825 -35.954 4.943   1.00 33.37  ? 652 HOH C O   1 
HETATM 10792 O  O   . HOH Y 8 .   ? -68.519 -41.928 24.721  1.00 51.67  ? 653 HOH C O   1 
HETATM 10793 O  O   . HOH Y 8 .   ? -68.676 -29.245 10.529  1.00 29.27  ? 654 HOH C O   1 
HETATM 10794 O  O   . HOH Y 8 .   ? -50.160 -48.187 15.854  1.00 38.19  ? 655 HOH C O   1 
HETATM 10795 O  O   . HOH Y 8 .   ? -51.072 -27.376 20.782  1.00 36.60  ? 656 HOH C O   1 
HETATM 10796 O  O   . HOH Y 8 .   ? -74.529 -10.117 4.545   1.00 41.51  ? 657 HOH C O   1 
HETATM 10797 O  O   . HOH Y 8 .   ? -66.302 -39.492 -2.694  1.00 31.17  ? 658 HOH C O   1 
HETATM 10798 O  O   . HOH Y 8 .   ? -40.859 -49.324 -6.952  1.00 40.50  ? 659 HOH C O   1 
HETATM 10799 O  O   . HOH Y 8 .   ? -65.297 -11.101 -15.261 1.00 36.67  ? 660 HOH C O   1 
HETATM 10800 O  O   . HOH Y 8 .   ? -72.563 -31.727 -21.308 1.00 43.65  ? 661 HOH C O   1 
HETATM 10801 O  O   . HOH Y 8 .   ? -77.418 -20.397 -0.020  1.00 52.17  ? 662 HOH C O   1 
HETATM 10802 O  O   . HOH Y 8 .   ? -53.769 -54.068 -4.270  1.00 36.54  ? 663 HOH C O   1 
HETATM 10803 O  O   . HOH Y 8 .   ? -44.889 -30.819 16.394  1.00 44.52  ? 664 HOH C O   1 
HETATM 10804 O  O   . HOH Y 8 .   ? -58.606 -14.803 13.459  1.00 39.70  ? 665 HOH C O   1 
HETATM 10805 O  O   . HOH Y 8 .   ? -67.622 -39.279 4.250   1.00 24.28  ? 666 HOH C O   1 
HETATM 10806 O  O   . HOH Y 8 .   ? -49.716 -23.986 3.103   1.00 33.74  ? 667 HOH C O   1 
HETATM 10807 O  O   . HOH Y 8 .   ? -74.673 -30.928 16.797  1.00 33.66  ? 668 HOH C O   1 
HETATM 10808 O  O   . HOH Y 8 .   ? -76.892 -21.956 -1.898  1.00 36.10  ? 669 HOH C O   1 
HETATM 10809 O  O   . HOH Y 8 .   ? -65.110 -22.130 27.157  1.00 48.10  ? 670 HOH C O   1 
HETATM 10810 O  O   . HOH Y 8 .   ? -56.507 -40.044 8.355   1.00 25.37  ? 671 HOH C O   1 
HETATM 10811 O  O   . HOH Y 8 .   ? -61.254 -34.025 31.436  1.00 43.12  ? 672 HOH C O   1 
HETATM 10812 O  O   . HOH Y 8 .   ? -48.005 -35.443 -9.903  1.00 21.94  ? 673 HOH C O   1 
HETATM 10813 O  O   . HOH Y 8 .   ? -60.008 -50.853 -1.072  1.00 41.18  ? 674 HOH C O   1 
HETATM 10814 O  O   . HOH Y 8 .   ? -54.018 -41.007 8.751   1.00 27.55  ? 675 HOH C O   1 
HETATM 10815 O  O   . HOH Y 8 .   ? -53.616 -34.839 22.090  1.00 38.30  ? 676 HOH C O   1 
HETATM 10816 O  O   . HOH Y 8 .   ? -57.851 -4.843  -12.528 1.00 32.74  ? 677 HOH C O   1 
HETATM 10817 O  O   . HOH Y 8 .   ? -56.171 -27.159 -2.568  1.00 30.39  ? 678 HOH C O   1 
HETATM 10818 O  O   . HOH Y 8 .   ? -82.091 -33.952 10.769  1.00 34.15  ? 679 HOH C O   1 
HETATM 10819 O  O   . HOH Y 8 .   ? -67.472 -28.954 -19.056 1.00 39.87  ? 680 HOH C O   1 
HETATM 10820 O  O   . HOH Y 8 .   ? -73.613 -16.833 12.140  1.00 38.40  ? 681 HOH C O   1 
HETATM 10821 O  O   . HOH Y 8 .   ? -75.841 -31.540 -3.472  1.00 40.11  ? 682 HOH C O   1 
HETATM 10822 O  O   . HOH Y 8 .   ? -59.307 -33.072 -5.242  1.00 22.80  ? 683 HOH C O   1 
HETATM 10823 O  O   . HOH Y 8 .   ? -82.090 -30.482 5.720   1.00 36.95  ? 684 HOH C O   1 
HETATM 10824 O  O   . HOH Y 8 .   ? -54.764 -38.512 23.727  1.00 48.45  ? 685 HOH C O   1 
HETATM 10825 O  O   . HOH Y 8 .   ? -51.276 -40.767 7.603   1.00 32.13  ? 686 HOH C O   1 
HETATM 10826 O  O   . HOH Y 8 .   ? -54.833 -47.655 5.756   1.00 27.20  ? 687 HOH C O   1 
HETATM 10827 O  O   . HOH Y 8 .   ? -55.433 -39.925 21.265  1.00 33.47  ? 688 HOH C O   1 
HETATM 10828 O  O   . HOH Y 8 .   ? -67.214 -9.683  1.627   1.00 42.79  ? 689 HOH C O   1 
HETATM 10829 O  O   . HOH Y 8 .   ? -59.523 -49.233 12.165  1.00 46.59  ? 690 HOH C O   1 
HETATM 10830 O  O   . HOH Y 8 .   ? -56.827 -24.258 27.698  1.00 43.85  ? 691 HOH C O   1 
HETATM 10831 O  O   . HOH Y 8 .   ? -82.404 -33.706 13.302  1.00 48.46  ? 692 HOH C O   1 
HETATM 10832 O  O   . HOH Y 8 .   ? -65.392 -47.047 13.398  1.00 36.03  ? 693 HOH C O   1 
HETATM 10833 O  O   . HOH Y 8 .   ? -61.345 -42.571 21.459  1.00 38.34  ? 694 HOH C O   1 
HETATM 10834 O  O   . HOH Y 8 .   ? -77.534 -30.140 -5.018  1.00 35.55  ? 695 HOH C O   1 
HETATM 10835 O  O   . HOH Y 8 .   ? -41.350 -24.732 -6.624  1.00 50.73  ? 696 HOH C O   1 
HETATM 10836 O  O   . HOH Y 8 .   ? -37.977 -36.321 -10.181 1.00 34.33  ? 697 HOH C O   1 
HETATM 10837 O  O   . HOH Y 8 .   ? -52.196 -24.104 2.467   1.00 32.83  ? 698 HOH C O   1 
HETATM 10838 O  O   . HOH Y 8 .   ? -69.838 -39.629 19.234  1.00 34.66  ? 699 HOH C O   1 
HETATM 10839 O  O   . HOH Y 8 .   ? -62.821 -25.947 -15.629 1.00 39.30  ? 700 HOH C O   1 
HETATM 10840 O  O   . HOH Y 8 .   ? -56.236 -33.723 -5.203  1.00 26.13  ? 701 HOH C O   1 
HETATM 10841 O  O   . HOH Y 8 .   ? -57.857 -26.912 13.862  1.00 30.30  ? 702 HOH C O   1 
HETATM 10842 O  O   . HOH Y 8 .   ? -65.923 -11.846 4.882   1.00 47.37  ? 703 HOH C O   1 
HETATM 10843 O  O   . HOH Y 8 .   ? -64.803 -44.562 -3.377  1.00 32.89  ? 704 HOH C O   1 
HETATM 10844 O  O   . HOH Y 8 .   ? -78.876 -15.690 5.185   1.00 43.02  ? 705 HOH C O   1 
HETATM 10845 O  O   . HOH Y 8 .   ? -39.908 -21.089 8.405   1.00 33.89  ? 706 HOH C O   1 
HETATM 10846 O  O   . HOH Y 8 .   ? -72.934 -44.728 2.594   1.00 43.67  ? 707 HOH C O   1 
HETATM 10847 O  O   . HOH Y 8 .   ? -58.370 -53.499 5.994   1.00 39.16  ? 708 HOH C O   1 
HETATM 10848 O  O   . HOH Y 8 .   ? -57.584 -22.309 -14.027 1.00 35.77  ? 709 HOH C O   1 
HETATM 10849 O  O   . HOH Y 8 .   ? -71.000 -39.830 22.795  1.00 50.12  ? 710 HOH C O   1 
HETATM 10850 O  O   . HOH Y 8 .   ? -59.329 -49.688 5.587   1.00 32.67  ? 711 HOH C O   1 
HETATM 10851 O  O   . HOH Y 8 .   ? -63.367 -23.736 -20.463 1.00 38.63  ? 712 HOH C O   1 
HETATM 10852 O  O   . HOH Y 8 .   ? -68.971 -14.865 5.065   1.00 39.36  ? 713 HOH C O   1 
HETATM 10853 O  O   . HOH Y 8 .   ? -72.906 -40.183 -14.492 1.00 28.62  ? 714 HOH C O   1 
HETATM 10854 O  O   . HOH Y 8 .   ? -40.110 -41.908 -18.057 1.00 29.49  ? 715 HOH C O   1 
HETATM 10855 O  O   . HOH Y 8 .   ? -73.450 -39.428 -17.569 1.00 46.35  ? 716 HOH C O   1 
HETATM 10856 O  O   . HOH Y 8 .   ? -60.508 -22.519 3.992   1.00 32.73  ? 717 HOH C O   1 
HETATM 10857 O  O   . HOH Y 8 .   ? -56.937 -19.735 22.969  1.00 42.61  ? 718 HOH C O   1 
HETATM 10858 O  O   . HOH Y 8 .   ? -64.046 -43.706 -12.819 1.00 42.28  ? 719 HOH C O   1 
HETATM 10859 O  O   . HOH Y 8 .   ? -53.884 -48.365 8.196   1.00 30.24  ? 720 HOH C O   1 
HETATM 10860 O  O   . HOH Y 8 .   ? -77.717 -26.509 1.741   1.00 35.62  ? 721 HOH C O   1 
HETATM 10861 O  O   . HOH Y 8 .   ? -81.404 -22.199 4.862   1.00 36.62  ? 722 HOH C O   1 
HETATM 10862 O  O   . HOH Y 8 .   ? -53.152 -51.521 10.931  1.00 36.37  ? 723 HOH C O   1 
HETATM 10863 O  O   . HOH Y 8 .   ? -73.794 -18.645 -18.035 1.00 41.33  ? 724 HOH C O   1 
HETATM 10864 O  O   . HOH Y 8 .   ? -35.948 -29.847 -5.435  1.00 46.24  ? 725 HOH C O   1 
HETATM 10865 O  O   . HOH Y 8 .   ? -74.377 -43.590 4.024   1.00 39.70  ? 726 HOH C O   1 
HETATM 10866 O  O   . HOH Y 8 .   ? -76.400 -28.028 -0.128  1.00 28.35  ? 727 HOH C O   1 
HETATM 10867 O  O   . HOH Y 8 .   ? -70.554 -44.640 14.076  1.00 44.99  ? 728 HOH C O   1 
HETATM 10868 O  O   . HOH Y 8 .   ? -62.340 -14.650 5.870   1.00 44.29  ? 729 HOH C O   1 
HETATM 10869 O  O   . HOH Y 8 .   ? -51.691 -20.396 -6.859  1.00 33.56  ? 730 HOH C O   1 
HETATM 10870 O  O   . HOH Y 8 .   ? -71.057 -23.840 23.242  1.00 49.60  ? 731 HOH C O   1 
HETATM 10871 O  O   . HOH Y 8 .   ? -76.739 -37.226 3.766   1.00 35.07  ? 732 HOH C O   1 
HETATM 10872 O  O   . HOH Y 8 .   ? -57.568 -30.742 15.401  1.00 29.26  ? 733 HOH C O   1 
HETATM 10873 O  O   . HOH Y 8 .   ? -75.417 -32.683 14.649  1.00 40.95  ? 734 HOH C O   1 
HETATM 10874 O  O   . HOH Y 8 .   ? -40.527 -42.642 3.837   1.00 37.17  ? 735 HOH C O   1 
HETATM 10875 O  O   . HOH Y 8 .   ? -58.281 -34.104 -2.924  1.00 26.35  ? 736 HOH C O   1 
HETATM 10876 O  O   . HOH Y 8 .   ? -49.830 -29.892 17.626  1.00 34.72  ? 737 HOH C O   1 
HETATM 10877 O  O   . HOH Y 8 .   ? -63.239 -10.335 1.693   1.00 44.04  ? 738 HOH C O   1 
HETATM 10878 O  O   . HOH Y 8 .   ? -47.225 -44.295 -8.662  1.00 28.76  ? 739 HOH C O   1 
HETATM 10879 O  O   . HOH Y 8 .   ? -62.511 -46.350 -3.056  1.00 29.22  ? 740 HOH C O   1 
HETATM 10880 O  O   . HOH Y 8 .   ? -79.838 -29.141 -17.530 1.00 39.92  ? 741 HOH C O   1 
HETATM 10881 O  O   . HOH Y 8 .   ? -56.412 -29.757 -11.937 1.00 42.81  ? 742 HOH C O   1 
HETATM 10882 O  O   . HOH Y 8 .   ? -71.683 -16.173 6.470   1.00 30.88  ? 743 HOH C O   1 
HETATM 10883 O  O   . HOH Y 8 .   ? -51.467 -59.880 5.723   1.00 50.08  ? 744 HOH C O   1 
HETATM 10884 O  O   . HOH Y 8 .   ? -55.633 -50.418 12.080  1.00 34.66  ? 745 HOH C O   1 
HETATM 10885 O  O   . HOH Y 8 .   ? -57.608 -47.561 6.549   1.00 23.73  ? 746 HOH C O   1 
HETATM 10886 O  O   . HOH Y 8 .   ? -68.495 -41.631 -13.609 1.00 46.36  ? 747 HOH C O   1 
HETATM 10887 O  O   . HOH Y 8 .   ? -81.892 -22.915 -9.692  1.00 48.09  ? 748 HOH C O   1 
HETATM 10888 O  O   . HOH Y 8 .   ? -48.076 -36.539 12.316  1.00 48.23  ? 749 HOH C O   1 
HETATM 10889 O  O   . HOH Y 8 .   ? -69.425 -11.232 2.277   1.00 38.44  ? 750 HOH C O   1 
HETATM 10890 O  O   . HOH Y 8 .   ? -52.697 -22.318 0.657   1.00 34.46  ? 751 HOH C O   1 
HETATM 10891 O  O   . HOH Y 8 .   ? -77.547 -25.132 26.028  1.00 52.42  ? 752 HOH C O   1 
HETATM 10892 O  O   . HOH Y 8 .   ? -52.934 -46.236 17.711  1.00 38.51  ? 753 HOH C O   1 
HETATM 10893 O  O   . HOH Y 8 .   ? -57.810 -36.344 -20.852 1.00 32.19  ? 754 HOH C O   1 
HETATM 10894 O  O   . HOH Y 8 .   ? -45.175 -28.164 -1.970  1.00 31.94  ? 755 HOH C O   1 
HETATM 10895 O  O   . HOH Y 8 .   ? -75.453 -20.665 -21.493 1.00 49.55  ? 756 HOH C O   1 
HETATM 10896 O  O   . HOH Y 8 .   ? -61.007 -46.309 4.601   1.00 23.46  ? 757 HOH C O   1 
HETATM 10897 O  O   . HOH Y 8 .   ? -54.072 -19.403 24.235  1.00 47.63  ? 758 HOH C O   1 
HETATM 10898 O  O   . HOH Y 8 .   ? -57.911 -15.433 8.657   1.00 40.42  ? 759 HOH C O   1 
HETATM 10899 O  O   . HOH Y 8 .   ? -69.577 -17.979 -16.379 1.00 31.67  ? 760 HOH C O   1 
HETATM 10900 O  O   . HOH Y 8 .   ? -59.140 -41.188 -21.710 1.00 44.21  ? 761 HOH C O   1 
HETATM 10901 O  O   . HOH Y 8 .   ? -45.687 -23.385 -10.179 1.00 33.61  ? 762 HOH C O   1 
HETATM 10902 O  O   . HOH Y 8 .   ? -57.904 -28.937 22.087  1.00 33.48  ? 763 HOH C O   1 
HETATM 10903 O  O   . HOH Y 8 .   ? -51.305 -44.176 17.449  1.00 39.59  ? 764 HOH C O   1 
HETATM 10904 O  O   . HOH Y 8 .   ? -63.749 -11.297 14.934  1.00 55.02  ? 765 HOH C O   1 
HETATM 10905 O  O   . HOH Y 8 .   ? -49.738 -34.942 -5.911  1.00 33.88  ? 766 HOH C O   1 
HETATM 10906 O  O   . HOH Y 8 .   ? -49.536 -21.399 1.408   1.00 53.29  ? 767 HOH C O   1 
HETATM 10907 O  O   . HOH Y 8 .   ? -36.119 -47.195 -12.062 1.00 48.63  ? 768 HOH C O   1 
HETATM 10908 O  O   . HOH Y 8 .   ? -45.994 -26.432 -0.313  1.00 26.88  ? 769 HOH C O   1 
HETATM 10909 O  O   . HOH Y 8 .   ? -57.874 -43.299 22.234  1.00 46.32  ? 770 HOH C O   1 
HETATM 10910 O  O   . HOH Y 8 .   ? -67.922 -46.022 3.328   1.00 41.04  ? 771 HOH C O   1 
HETATM 10911 O  O   . HOH Y 8 .   ? -78.735 -28.142 -10.043 1.00 26.16  ? 772 HOH C O   1 
HETATM 10912 O  O   . HOH Y 8 .   ? -62.784 -21.907 25.513  1.00 35.43  ? 773 HOH C O   1 
HETATM 10913 O  O   . HOH Y 8 .   ? -33.893 -44.261 -3.434  1.00 45.04  ? 774 HOH C O   1 
HETATM 10914 O  O   . HOH Y 8 .   ? -77.388 -13.035 -5.797  1.00 51.23  ? 775 HOH C O   1 
HETATM 10915 O  O   . HOH Y 8 .   ? -49.214 -47.418 -8.687  1.00 34.15  ? 776 HOH C O   1 
HETATM 10916 O  O   . HOH Y 8 .   ? -49.224 -50.023 -16.072 1.00 40.11  ? 777 HOH C O   1 
HETATM 10917 O  O   . HOH Y 8 .   ? -57.194 -25.969 -14.802 1.00 45.48  ? 778 HOH C O   1 
HETATM 10918 O  O   . HOH Y 8 .   ? -73.607 -30.047 28.647  1.00 47.83  ? 779 HOH C O   1 
HETATM 10919 O  O   . HOH Y 8 .   ? -56.513 -13.742 -17.288 1.00 27.05  ? 780 HOH C O   1 
HETATM 10920 O  O   . HOH Y 8 .   ? -55.513 -16.448 4.715   1.00 50.65  ? 781 HOH C O   1 
HETATM 10921 O  O   . HOH Y 8 .   ? -72.322 -13.184 -14.590 1.00 51.20  ? 782 HOH C O   1 
HETATM 10922 O  O   . HOH Y 8 .   ? -58.620 -34.189 30.794  1.00 40.63  ? 783 HOH C O   1 
HETATM 10923 O  O   . HOH Y 8 .   ? -78.374 -24.025 -1.622  1.00 47.66  ? 784 HOH C O   1 
HETATM 10924 O  O   . HOH Y 8 .   ? -42.456 -59.040 7.711   1.00 44.82  ? 785 HOH C O   1 
HETATM 10925 O  O   . HOH Y 8 .   ? -60.251 -51.643 7.182   1.00 48.59  ? 786 HOH C O   1 
HETATM 10926 O  O   . HOH Y 8 .   ? -69.179 -13.956 -14.101 1.00 27.73  ? 787 HOH C O   1 
HETATM 10927 O  O   . HOH Y 8 .   ? -33.988 -34.159 -0.015  1.00 48.37  ? 788 HOH C O   1 
HETATM 10928 O  O   . HOH Y 8 .   ? -65.008 -20.544 24.204  1.00 43.28  ? 789 HOH C O   1 
HETATM 10929 O  O   . HOH Y 8 .   ? -53.024 -55.838 -0.006  1.00 51.20  ? 790 HOH C O   1 
HETATM 10930 O  O   . HOH Y 8 .   ? -49.859 -22.313 25.123  1.00 47.64  ? 791 HOH C O   1 
HETATM 10931 O  O   . HOH Y 8 .   ? -49.864 -37.445 -9.778  1.00 36.70  ? 792 HOH C O   1 
HETATM 10932 O  O   . HOH Y 8 .   ? -56.110 -32.230 28.630  1.00 42.60  ? 793 HOH C O   1 
HETATM 10933 O  O   . HOH Y 8 .   ? -39.202 -35.697 -13.885 1.00 45.81  ? 794 HOH C O   1 
HETATM 10934 O  O   . HOH Y 8 .   ? -58.687 -6.166  -5.530  1.00 36.49  ? 795 HOH C O   1 
HETATM 10935 O  O   . HOH Y 8 .   ? -76.729 -42.306 7.799   1.00 44.52  ? 796 HOH C O   1 
HETATM 10936 O  O   . HOH Y 8 .   ? -30.352 -44.243 -3.211  1.00 60.65  ? 797 HOH C O   1 
HETATM 10937 O  O   . HOH Y 8 .   ? -43.889 -48.035 -17.567 1.00 42.91  ? 798 HOH C O   1 
HETATM 10938 O  O   . HOH Y 8 .   ? -50.701 -15.921 12.661  1.00 48.96  ? 799 HOH C O   1 
HETATM 10939 O  O   . HOH Y 8 .   ? -51.463 -30.635 22.020  1.00 38.99  ? 800 HOH C O   1 
HETATM 10940 O  O   . HOH Y 8 .   ? -77.682 -10.088 -13.347 1.00 55.01  ? 801 HOH C O   1 
HETATM 10941 O  O   . HOH Y 8 .   ? -32.807 -42.010 -10.301 1.00 40.96  ? 802 HOH C O   1 
HETATM 10942 O  O   . HOH Y 8 .   ? -41.757 -33.579 10.854  1.00 33.34  ? 803 HOH C O   1 
HETATM 10943 O  O   . HOH Y 8 .   ? -62.745 -8.860  -0.080  1.00 48.25  ? 804 HOH C O   1 
HETATM 10944 O  O   . HOH Y 8 .   ? -69.956 -10.276 18.883  1.00 44.72  ? 805 HOH C O   1 
HETATM 10945 O  O   . HOH Y 8 .   ? -65.684 -48.135 -9.636  1.00 31.72  ? 806 HOH C O   1 
HETATM 10946 O  O   . HOH Y 8 .   ? -60.627 -45.152 -18.852 1.00 44.48  ? 807 HOH C O   1 
HETATM 10947 O  O   . HOH Y 8 .   ? -79.480 -25.906 -8.965  1.00 41.06  ? 808 HOH C O   1 
HETATM 10948 O  O   . HOH Y 8 .   ? -67.097 -46.177 19.678  1.00 43.24  ? 809 HOH C O   1 
HETATM 10949 O  O   . HOH Y 8 .   ? -77.022 -40.092 20.062  1.00 58.15  ? 810 HOH C O   1 
HETATM 10950 O  O   . HOH Y 8 .   ? -67.086 -41.176 -21.304 1.00 51.93  ? 811 HOH C O   1 
HETATM 10951 O  O   . HOH Y 8 .   ? -37.323 -47.903 4.843   1.00 48.29  ? 812 HOH C O   1 
HETATM 10952 O  O   . HOH Y 8 .   ? -59.593 -53.246 3.362   1.00 49.67  ? 813 HOH C O   1 
HETATM 10953 O  O   . HOH Y 8 .   ? -65.395 -9.287  -10.306 1.00 31.37  ? 814 HOH C O   1 
HETATM 10954 O  O   . HOH Y 8 .   ? -47.700 -24.741 -11.500 1.00 31.00  ? 815 HOH C O   1 
HETATM 10955 O  O   . HOH Y 8 .   ? -60.616 -37.939 -26.740 1.00 36.16  ? 816 HOH C O   1 
HETATM 10956 O  O   . HOH Y 8 .   ? -61.902 -49.711 4.716   1.00 35.60  ? 817 HOH C O   1 
HETATM 10957 O  O   . HOH Y 8 .   ? -55.901 -15.506 12.276  1.00 41.80  ? 818 HOH C O   1 
HETATM 10958 O  O   . HOH Y 8 .   ? -77.317 -26.957 -2.340  1.00 40.22  ? 819 HOH C O   1 
HETATM 10959 O  O   . HOH Y 8 .   ? -52.410 -19.390 -3.338  1.00 47.37  ? 820 HOH C O   1 
HETATM 10960 O  O   . HOH Y 8 .   ? -53.948 -22.967 -13.452 1.00 33.73  ? 821 HOH C O   1 
HETATM 10961 O  O   . HOH Y 8 .   ? -55.224 -16.182 -17.789 1.00 30.06  ? 822 HOH C O   1 
HETATM 10962 O  O   . HOH Y 8 .   ? -60.212 -9.621  -2.173  1.00 33.86  ? 823 HOH C O   1 
HETATM 10963 O  O   . HOH Y 8 .   ? -51.801 -15.796 5.852   1.00 38.76  ? 824 HOH C O   1 
HETATM 10964 O  O   . HOH Y 8 .   ? -78.176 -18.024 -16.356 1.00 39.58  ? 825 HOH C O   1 
HETATM 10965 O  O   . HOH Y 8 .   ? -75.290 -17.604 -15.712 1.00 45.75  ? 826 HOH C O   1 
HETATM 10966 O  O   . HOH Y 8 .   ? -60.165 -34.008 10.582  1.00 38.66  ? 827 HOH C O   1 
HETATM 10967 O  O   . HOH Y 8 .   ? -58.950 -40.350 -24.802 1.00 46.30  ? 828 HOH C O   1 
HETATM 10968 O  O   . HOH Y 8 .   ? -57.037 -33.767 -8.339  1.00 34.13  ? 829 HOH C O   1 
HETATM 10969 O  O   . HOH Y 8 .   ? -65.852 -3.234  -0.862  1.00 47.46  ? 830 HOH C O   1 
HETATM 10970 O  O   . HOH Y 8 .   ? -54.348 -25.198 27.753  1.00 53.54  ? 831 HOH C O   1 
HETATM 10971 O  O   . HOH Y 8 .   ? -66.883 -14.892 -15.408 1.00 47.46  ? 832 HOH C O   1 
HETATM 10972 O  O   . HOH Y 8 .   ? -65.342 -37.768 -21.040 1.00 47.81  ? 833 HOH C O   1 
HETATM 10973 O  O   . HOH Y 8 .   ? -55.338 -10.787 -16.805 1.00 21.32  ? 834 HOH C O   1 
HETATM 10974 O  O   . HOH Y 8 .   ? -37.799 -45.255 -20.374 1.00 55.43  ? 835 HOH C O   1 
HETATM 10975 O  O   . HOH Y 8 .   ? -48.849 -27.324 18.886  1.00 43.12  ? 836 HOH C O   1 
HETATM 10976 O  O   . HOH Y 8 .   ? -69.829 -25.087 -20.305 1.00 27.40  ? 837 HOH C O   1 
HETATM 10977 O  O   . HOH Y 8 .   ? -81.500 -26.849 3.464   1.00 42.94  ? 838 HOH C O   1 
HETATM 10978 O  O   . HOH Y 8 .   ? -42.425 -53.348 -9.195  1.00 50.82  ? 839 HOH C O   1 
HETATM 10979 O  O   . HOH Y 8 .   ? -76.594 -45.494 -2.068  1.00 52.04  ? 840 HOH C O   1 
HETATM 10980 O  O   . HOH Y 8 .   ? -49.119 -17.335 23.134  1.00 57.18  ? 841 HOH C O   1 
HETATM 10981 O  O   . HOH Y 8 .   ? -55.084 -31.873 -10.240 1.00 37.57  ? 842 HOH C O   1 
HETATM 10982 O  O   . HOH Y 8 .   ? -53.312 -13.767 13.090  1.00 51.67  ? 843 HOH C O   1 
HETATM 10983 O  O   . HOH Y 8 .   ? -52.825 -33.993 26.014  1.00 57.00  ? 844 HOH C O   1 
HETATM 10984 O  O   . HOH Y 8 .   ? -78.927 -33.361 3.997   1.00 34.64  ? 845 HOH C O   1 
HETATM 10985 O  O   . HOH Y 8 .   ? -81.911 -37.782 7.374   1.00 46.48  ? 846 HOH C O   1 
HETATM 10986 O  O   . HOH Y 8 .   ? -80.124 -22.788 -8.284  1.00 51.56  ? 847 HOH C O   1 
HETATM 10987 O  O   . HOH Y 8 .   ? -70.617 -27.778 -21.365 1.00 48.98  ? 848 HOH C O   1 
HETATM 10988 O  O   . HOH Y 8 .   ? -62.504 -16.277 20.560  1.00 50.30  ? 849 HOH C O   1 
HETATM 10989 O  O   . HOH Y 8 .   ? -81.118 -20.062 3.324   1.00 46.27  ? 850 HOH C O   1 
HETATM 10990 O  O   . HOH Y 8 .   ? -44.112 -24.571 -1.019  1.00 43.84  ? 851 HOH C O   1 
HETATM 10991 O  O   . HOH Y 8 .   ? -73.440 -15.374 -15.917 1.00 49.03  ? 852 HOH C O   1 
HETATM 10992 O  O   . HOH Y 8 .   ? -43.273 -30.356 14.314  1.00 45.97  ? 853 HOH C O   1 
HETATM 10993 O  O   . HOH Y 8 .   ? -71.838 -41.522 19.441  1.00 49.28  ? 854 HOH C O   1 
HETATM 10994 O  O   . HOH Y 8 .   ? -80.659 -20.707 0.091   1.00 58.86  ? 855 HOH C O   1 
HETATM 10995 O  O   . HOH Y 8 .   ? -66.780 -49.466 27.205  1.00 57.79  ? 856 HOH C O   1 
HETATM 10996 O  O   . HOH Y 8 .   ? -68.484 -29.506 -21.152 1.00 44.81  ? 857 HOH C O   1 
HETATM 10997 O  O   . HOH Y 8 .   ? -77.353 -30.805 -0.296  1.00 52.94  ? 858 HOH C O   1 
HETATM 10998 O  O   . HOH Y 8 .   ? -60.704 -14.570 8.180   1.00 48.20  ? 859 HOH C O   1 
HETATM 10999 O  O   . HOH Y 8 .   ? -59.631 -25.925 34.566  1.00 61.85  ? 860 HOH C O   1 
HETATM 11000 O  O   . HOH Y 8 .   ? -39.732 -57.788 9.215   1.00 56.74  ? 861 HOH C O   1 
HETATM 11001 O  O   . HOH Y 8 .   ? -78.993 -26.962 14.076  1.00 48.48  ? 862 HOH C O   1 
HETATM 11002 O  O   . HOH Y 8 .   ? -48.481 -15.918 14.222  1.00 44.75  ? 863 HOH C O   1 
HETATM 11003 O  O   . HOH Y 8 .   ? -83.182 -28.375 4.860   1.00 48.70  ? 864 HOH C O   1 
HETATM 11004 O  O   . HOH Y 8 .   ? -34.435 -44.867 -16.921 1.00 63.01  ? 865 HOH C O   1 
HETATM 11005 O  O   . HOH Y 8 .   ? -83.373 -35.677 9.117   1.00 49.80  ? 866 HOH C O   1 
HETATM 11006 O  O   . HOH Y 8 .   ? -51.873 -32.986 23.195  1.00 52.28  ? 867 HOH C O   1 
HETATM 11007 O  O   . HOH Y 8 .   ? -61.946 -11.393 12.581  1.00 62.76  ? 868 HOH C O   1 
HETATM 11008 O  O   . HOH Y 8 .   ? -68.883 -12.463 4.489   1.00 46.28  ? 869 HOH C O   1 
HETATM 11009 O  O   . HOH Y 8 .   ? -71.698 -42.497 21.817  1.00 55.41  ? 870 HOH C O   1 
HETATM 11010 O  O   . HOH Y 8 .   ? -74.405 -41.223 18.483  1.00 52.97  ? 871 HOH C O   1 
HETATM 11011 O  O   . HOH Y 8 .   ? -59.803 -12.779 12.019  1.00 58.89  ? 872 HOH C O   1 
HETATM 11012 O  O   . HOH Y 8 .   ? -61.742 -51.957 3.132   1.00 45.61  ? 873 HOH C O   1 
HETATM 11013 O  O   . HOH Y 8 .   ? -81.261 -24.738 10.794  1.00 46.36  ? 874 HOH C O   1 
HETATM 11014 O  O   . HOH Y 8 .   ? -47.259 -18.593 21.254  1.00 59.34  ? 875 HOH C O   1 
HETATM 11015 O  O   . HOH Y 8 .   ? -81.642 -32.248 3.837   1.00 39.58  ? 876 HOH C O   1 
HETATM 11016 O  O   . HOH Y 8 .   ? -82.414 -23.933 3.267   1.00 46.72  ? 877 HOH C O   1 
HETATM 11017 O  O   . HOH Y 8 .   ? -48.133 -20.901 -1.481  1.00 54.49  ? 878 HOH C O   1 
HETATM 11018 O  O   . HOH Y 8 .   ? -40.371 -36.178 10.244  1.00 51.18  ? 879 HOH C O   1 
HETATM 11019 O  O   . HOH Y 8 .   ? -66.955 -20.567 25.894  1.00 47.05  ? 880 HOH C O   1 
HETATM 11020 O  O   . HOH Y 8 .   ? -40.279 -25.796 10.785  1.00 51.29  ? 881 HOH C O   1 
HETATM 11021 O  O   . HOH Y 8 .   ? -49.671 -35.038 23.336  1.00 51.70  ? 882 HOH C O   1 
HETATM 11022 O  O   . HOH Y 8 .   ? -74.470 -43.711 16.639  1.00 51.13  ? 883 HOH C O   1 
# 
