data_8VPQ
# 
_entry.id   8VPQ 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.399 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8VPQ         pdb_00008vpq 10.2210/pdb8vpq/pdb 
WWPDB D_1000280695 ?            ?                   
EMDB  EMD-43413    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
1 'Structure model' 1 0 2024-11-27 
2 'Structure model' 1 1 2024-12-04 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 2 'Structure model' 'Data collection' 
2 2 'Structure model' 'Data processing' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 2 'Structure model' em_3d_reconstruction 
2 2 'Structure model' em_admin             
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1 2 'Structure model' '_em_3d_reconstruction.num_particles' 
2 2 'Structure model' '_em_admin.last_update'               
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8VPQ 
_pdbx_database_status.recvd_initial_deposition_date   2024-01-16 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'The structure of LSD1-CoREST-HDAC1 in complex with KBTBD4IPR310delinsTTYML' 
_pdbx_database_related.db_id          EMD-43413 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              nzheng@uw.edu 
_pdbx_contact_author.name_first         Ning 
_pdbx_contact_author.name_last          Zheng 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-1039-1581 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Xie, X.'   1 ? 
'Liau, B.'  2 ? 
'Zheng, N.' 3 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
'Molecular Mechanism Underlying KBTBD4 Cancer Mutation-Driven Degradation of HDAC Corepressor Complexes' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Xie, X.'   1 ? 
primary 'Liau, B.'  2 ? 
primary 'Zheng, N.' 3 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Isoform 2 of Kelch repeat and BTB domain-containing protein 4' 60213.977 2 ?                ? ? ? 
2 polymer     man 'Histone deacetylase 1'                                         55178.906 1 3.5.1.98,3.5.1.- ? ? ? 
3 polymer     man 'REST corepressor 1'                                            53401.352 1 ?                ? ? ? 
4 non-polymer syn 'ZINC ION'                                                      65.409    1 ?                ? ? ? 
5 non-polymer syn 'INOSITOL HEXAKISPHOSPHATE'                                     660.035   1 ?                ? ? ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
1 'BTB and kelch domain-containing protein 4'                 
2 'HD1,Protein deacetylase HDAC1,Protein decrotonylase HDAC1' 
3 'Protein CoREST'                                            
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;MKGGNADSWQREKLASMESPEEPGASMDENYFVNYTFKDRSHSGRVAQGIMKLCLEEELFADVTISVEGREFQLHRLVLS
AQSCFFRSMFTSNLKEAHNRVIVLQDVSESVFQLLVDYIYHGTVKLRAEELQEIYEVSDMYQLTSLFEECSRFLARTVQV
GNCLQVMWLADRHSDPELYTAAKHCAKTHLAQLQNTEEFLHLPHRLLTDIISDGVPCSQNPTEAIEAWINFNKEEREAFA
ESLRTSLKEIGENVHIYLIGKESSRTHSLAVSLHCAEDDSISVSGQNSLCHQITAACKHGGDLYVVGGSTTYMLRMWKCN
NATVDWEWCAPLPRDRLQHTLVSVPGKDAIYSLGGKTLQDTLSNAVIYYRVGDNVWTETTQLEVAVSGAAGANLNGIIYL
LGGEENDLDFFTKPSRLIQCFDTETDKCHVKPYVLPFAGRMHAAVHKDLVFIVAEGDSLVCYNPLLDSFTRLCLPEAWSS
APSLWKIASCNGSIYVFRDRYKKGDANTYKLDPATSAVTVTRGIKVLLTNLQFVLA
;
;MKGGNADSWQREKLASMESPEEPGASMDENYFVNYTFKDRSHSGRVAQGIMKLCLEEELFADVTISVEGREFQLHRLVLS
AQSCFFRSMFTSNLKEAHNRVIVLQDVSESVFQLLVDYIYHGTVKLRAEELQEIYEVSDMYQLTSLFEECSRFLARTVQV
GNCLQVMWLADRHSDPELYTAAKHCAKTHLAQLQNTEEFLHLPHRLLTDIISDGVPCSQNPTEAIEAWINFNKEEREAFA
ESLRTSLKEIGENVHIYLIGKESSRTHSLAVSLHCAEDDSISVSGQNSLCHQITAACKHGGDLYVVGGSTTYMLRMWKCN
NATVDWEWCAPLPRDRLQHTLVSVPGKDAIYSLGGKTLQDTLSNAVIYYRVGDNVWTETTQLEVAVSGAAGANLNGIIYL
LGGEENDLDFFTKPSRLIQCFDTETDKCHVKPYVLPFAGRMHAAVHKDLVFIVAEGDSLVCYNPLLDSFTRLCLPEAWSS
APSLWKIASCNGSIYVFRDRYKKGDANTYKLDPATSAVTVTRGIKVLLTNLQFVLA
;
A,B ? 
2 'polypeptide(L)' no no 
;MAQTQGTRRKVCYYYDGDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYHSDDYIKFLRSIR
PDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVASAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAI
LELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAI
FKPVMSKVMEMFQPSAVVLQCGSDSLSGDRLGCFNLTIKGHAKCVEFVKSFNLPMLMLGGGGYTIRNVARCWTYETAVAL
DTEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTNEYLEKIKQRLFENLRMLPHAPGVQMQAIPEDAIPEESGDEDEDD
PDKRISICSSDKRIACEEEFSDSEEEGEGGRKNSSNFKKAKRVKTEDEKEKDPEEKKEVTEEEKTKEEKPEAKGVKEEVK
LA
;
;MAQTQGTRRKVCYYYDGDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYHSDDYIKFLRSIR
PDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVASAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAI
LELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAI
FKPVMSKVMEMFQPSAVVLQCGSDSLSGDRLGCFNLTIKGHAKCVEFVKSFNLPMLMLGGGGYTIRNVARCWTYETAVAL
DTEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTNEYLEKIKQRLFENLRMLPHAPGVQMQAIPEDAIPEESGDEDEDD
PDKRISICSSDKRIACEEEFSDSEEEGEGGRKNSSNFKKAKRVKTEDEKEKDPEEKKEVTEEEKTKEEKPEAKGVKEEVK
LA
;
C   ? 
3 'polypeptide(L)' no no 
;MPAMVEKGPEVSGKRRGRNNAAASASAAAASAAASAACASPAATAASGAAASSASAAAASAAAAPNNGQNKSLAAAAPNG
NSSSNSWEEGSSGSSSDEEHGGGGMRVGPQYQAVVPDFDPAKLARRSQERDNLGMLVWSPNQNLSEAKLDEYIAIAKEKH
GYNMEQALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKTFHRIQQMLPDKSIASLVKFYYSWKKTR
TKTSVMDRHARKQKREREESEDELEEANGNNPIDIEVDQNKESKKEVPPTETVPQVKKEKHSTQAKNRAKRKPPKGMFLS
QEDVEAVSANATAATTVLRQLDMELVSVKRQIQNIKQTNSALKEKLDGGIEPYRLPEVIQKCNARWTTEEQLLAVQAIRK
YGRDFQAISDVIGNKSVVQVKNFFVNYRRRFNIDEVLQEWEAEHGKEETNGPSNQKPVKSPDNSIKMPEEEDEAPVLDVR
YASAS
;
;MPAMVEKGPEVSGKRRGRNNAAASASAAAASAAASAACASPAATAASGAAASSASAAAASAAAAPNNGQNKSLAAAAPNG
NSSSNSWEEGSSGSSSDEEHGGGGMRVGPQYQAVVPDFDPAKLARRSQERDNLGMLVWSPNQNLSEAKLDEYIAIAKEKH
GYNMEQALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKTFHRIQQMLPDKSIASLVKFYYSWKKTR
TKTSVMDRHARKQKREREESEDELEEANGNNPIDIEVDQNKESKKEVPPTETVPQVKKEKHSTQAKNRAKRKPPKGMFLS
QEDVEAVSANATAATTVLRQLDMELVSVKRQIQNIKQTNSALKEKLDGGIEPYRLPEVIQKCNARWTTEEQLLAVQAIRK
YGRDFQAISDVIGNKSVVQVKNFFVNYRRRFNIDEVLQEWEAEHGKEETNGPSNQKPVKSPDNSIKMPEEEDEAPVLDVR
YASAS
;
D   ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
4 'ZINC ION'                  ZN  
5 'INOSITOL HEXAKISPHOSPHATE' IHP 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   LYS n 
1 3   GLY n 
1 4   GLY n 
1 5   ASN n 
1 6   ALA n 
1 7   ASP n 
1 8   SER n 
1 9   TRP n 
1 10  GLN n 
1 11  ARG n 
1 12  GLU n 
1 13  LYS n 
1 14  LEU n 
1 15  ALA n 
1 16  SER n 
1 17  MET n 
1 18  GLU n 
1 19  SER n 
1 20  PRO n 
1 21  GLU n 
1 22  GLU n 
1 23  PRO n 
1 24  GLY n 
1 25  ALA n 
1 26  SER n 
1 27  MET n 
1 28  ASP n 
1 29  GLU n 
1 30  ASN n 
1 31  TYR n 
1 32  PHE n 
1 33  VAL n 
1 34  ASN n 
1 35  TYR n 
1 36  THR n 
1 37  PHE n 
1 38  LYS n 
1 39  ASP n 
1 40  ARG n 
1 41  SER n 
1 42  HIS n 
1 43  SER n 
1 44  GLY n 
1 45  ARG n 
1 46  VAL n 
1 47  ALA n 
1 48  GLN n 
1 49  GLY n 
1 50  ILE n 
1 51  MET n 
1 52  LYS n 
1 53  LEU n 
1 54  CYS n 
1 55  LEU n 
1 56  GLU n 
1 57  GLU n 
1 58  GLU n 
1 59  LEU n 
1 60  PHE n 
1 61  ALA n 
1 62  ASP n 
1 63  VAL n 
1 64  THR n 
1 65  ILE n 
1 66  SER n 
1 67  VAL n 
1 68  GLU n 
1 69  GLY n 
1 70  ARG n 
1 71  GLU n 
1 72  PHE n 
1 73  GLN n 
1 74  LEU n 
1 75  HIS n 
1 76  ARG n 
1 77  LEU n 
1 78  VAL n 
1 79  LEU n 
1 80  SER n 
1 81  ALA n 
1 82  GLN n 
1 83  SER n 
1 84  CYS n 
1 85  PHE n 
1 86  PHE n 
1 87  ARG n 
1 88  SER n 
1 89  MET n 
1 90  PHE n 
1 91  THR n 
1 92  SER n 
1 93  ASN n 
1 94  LEU n 
1 95  LYS n 
1 96  GLU n 
1 97  ALA n 
1 98  HIS n 
1 99  ASN n 
1 100 ARG n 
1 101 VAL n 
1 102 ILE n 
1 103 VAL n 
1 104 LEU n 
1 105 GLN n 
1 106 ASP n 
1 107 VAL n 
1 108 SER n 
1 109 GLU n 
1 110 SER n 
1 111 VAL n 
1 112 PHE n 
1 113 GLN n 
1 114 LEU n 
1 115 LEU n 
1 116 VAL n 
1 117 ASP n 
1 118 TYR n 
1 119 ILE n 
1 120 TYR n 
1 121 HIS n 
1 122 GLY n 
1 123 THR n 
1 124 VAL n 
1 125 LYS n 
1 126 LEU n 
1 127 ARG n 
1 128 ALA n 
1 129 GLU n 
1 130 GLU n 
1 131 LEU n 
1 132 GLN n 
1 133 GLU n 
1 134 ILE n 
1 135 TYR n 
1 136 GLU n 
1 137 VAL n 
1 138 SER n 
1 139 ASP n 
1 140 MET n 
1 141 TYR n 
1 142 GLN n 
1 143 LEU n 
1 144 THR n 
1 145 SER n 
1 146 LEU n 
1 147 PHE n 
1 148 GLU n 
1 149 GLU n 
1 150 CYS n 
1 151 SER n 
1 152 ARG n 
1 153 PHE n 
1 154 LEU n 
1 155 ALA n 
1 156 ARG n 
1 157 THR n 
1 158 VAL n 
1 159 GLN n 
1 160 VAL n 
1 161 GLY n 
1 162 ASN n 
1 163 CYS n 
1 164 LEU n 
1 165 GLN n 
1 166 VAL n 
1 167 MET n 
1 168 TRP n 
1 169 LEU n 
1 170 ALA n 
1 171 ASP n 
1 172 ARG n 
1 173 HIS n 
1 174 SER n 
1 175 ASP n 
1 176 PRO n 
1 177 GLU n 
1 178 LEU n 
1 179 TYR n 
1 180 THR n 
1 181 ALA n 
1 182 ALA n 
1 183 LYS n 
1 184 HIS n 
1 185 CYS n 
1 186 ALA n 
1 187 LYS n 
1 188 THR n 
1 189 HIS n 
1 190 LEU n 
1 191 ALA n 
1 192 GLN n 
1 193 LEU n 
1 194 GLN n 
1 195 ASN n 
1 196 THR n 
1 197 GLU n 
1 198 GLU n 
1 199 PHE n 
1 200 LEU n 
1 201 HIS n 
1 202 LEU n 
1 203 PRO n 
1 204 HIS n 
1 205 ARG n 
1 206 LEU n 
1 207 LEU n 
1 208 THR n 
1 209 ASP n 
1 210 ILE n 
1 211 ILE n 
1 212 SER n 
1 213 ASP n 
1 214 GLY n 
1 215 VAL n 
1 216 PRO n 
1 217 CYS n 
1 218 SER n 
1 219 GLN n 
1 220 ASN n 
1 221 PRO n 
1 222 THR n 
1 223 GLU n 
1 224 ALA n 
1 225 ILE n 
1 226 GLU n 
1 227 ALA n 
1 228 TRP n 
1 229 ILE n 
1 230 ASN n 
1 231 PHE n 
1 232 ASN n 
1 233 LYS n 
1 234 GLU n 
1 235 GLU n 
1 236 ARG n 
1 237 GLU n 
1 238 ALA n 
1 239 PHE n 
1 240 ALA n 
1 241 GLU n 
1 242 SER n 
1 243 LEU n 
1 244 ARG n 
1 245 THR n 
1 246 SER n 
1 247 LEU n 
1 248 LYS n 
1 249 GLU n 
1 250 ILE n 
1 251 GLY n 
1 252 GLU n 
1 253 ASN n 
1 254 VAL n 
1 255 HIS n 
1 256 ILE n 
1 257 TYR n 
1 258 LEU n 
1 259 ILE n 
1 260 GLY n 
1 261 LYS n 
1 262 GLU n 
1 263 SER n 
1 264 SER n 
1 265 ARG n 
1 266 THR n 
1 267 HIS n 
1 268 SER n 
1 269 LEU n 
1 270 ALA n 
1 271 VAL n 
1 272 SER n 
1 273 LEU n 
1 274 HIS n 
1 275 CYS n 
1 276 ALA n 
1 277 GLU n 
1 278 ASP n 
1 279 ASP n 
1 280 SER n 
1 281 ILE n 
1 282 SER n 
1 283 VAL n 
1 284 SER n 
1 285 GLY n 
1 286 GLN n 
1 287 ASN n 
1 288 SER n 
1 289 LEU n 
1 290 CYS n 
1 291 HIS n 
1 292 GLN n 
1 293 ILE n 
1 294 THR n 
1 295 ALA n 
1 296 ALA n 
1 297 CYS n 
1 298 LYS n 
1 299 HIS n 
1 300 GLY n 
1 301 GLY n 
1 302 ASP n 
1 303 LEU n 
1 304 TYR n 
1 305 VAL n 
1 306 VAL n 
1 307 GLY n 
1 308 GLY n 
1 309 SER n 
1 310 THR n 
1 311 THR n 
1 312 TYR n 
1 313 MET n 
1 314 LEU n 
1 315 ARG n 
1 316 MET n 
1 317 TRP n 
1 318 LYS n 
1 319 CYS n 
1 320 ASN n 
1 321 ASN n 
1 322 ALA n 
1 323 THR n 
1 324 VAL n 
1 325 ASP n 
1 326 TRP n 
1 327 GLU n 
1 328 TRP n 
1 329 CYS n 
1 330 ALA n 
1 331 PRO n 
1 332 LEU n 
1 333 PRO n 
1 334 ARG n 
1 335 ASP n 
1 336 ARG n 
1 337 LEU n 
1 338 GLN n 
1 339 HIS n 
1 340 THR n 
1 341 LEU n 
1 342 VAL n 
1 343 SER n 
1 344 VAL n 
1 345 PRO n 
1 346 GLY n 
1 347 LYS n 
1 348 ASP n 
1 349 ALA n 
1 350 ILE n 
1 351 TYR n 
1 352 SER n 
1 353 LEU n 
1 354 GLY n 
1 355 GLY n 
1 356 LYS n 
1 357 THR n 
1 358 LEU n 
1 359 GLN n 
1 360 ASP n 
1 361 THR n 
1 362 LEU n 
1 363 SER n 
1 364 ASN n 
1 365 ALA n 
1 366 VAL n 
1 367 ILE n 
1 368 TYR n 
1 369 TYR n 
1 370 ARG n 
1 371 VAL n 
1 372 GLY n 
1 373 ASP n 
1 374 ASN n 
1 375 VAL n 
1 376 TRP n 
1 377 THR n 
1 378 GLU n 
1 379 THR n 
1 380 THR n 
1 381 GLN n 
1 382 LEU n 
1 383 GLU n 
1 384 VAL n 
1 385 ALA n 
1 386 VAL n 
1 387 SER n 
1 388 GLY n 
1 389 ALA n 
1 390 ALA n 
1 391 GLY n 
1 392 ALA n 
1 393 ASN n 
1 394 LEU n 
1 395 ASN n 
1 396 GLY n 
1 397 ILE n 
1 398 ILE n 
1 399 TYR n 
1 400 LEU n 
1 401 LEU n 
1 402 GLY n 
1 403 GLY n 
1 404 GLU n 
1 405 GLU n 
1 406 ASN n 
1 407 ASP n 
1 408 LEU n 
1 409 ASP n 
1 410 PHE n 
1 411 PHE n 
1 412 THR n 
1 413 LYS n 
1 414 PRO n 
1 415 SER n 
1 416 ARG n 
1 417 LEU n 
1 418 ILE n 
1 419 GLN n 
1 420 CYS n 
1 421 PHE n 
1 422 ASP n 
1 423 THR n 
1 424 GLU n 
1 425 THR n 
1 426 ASP n 
1 427 LYS n 
1 428 CYS n 
1 429 HIS n 
1 430 VAL n 
1 431 LYS n 
1 432 PRO n 
1 433 TYR n 
1 434 VAL n 
1 435 LEU n 
1 436 PRO n 
1 437 PHE n 
1 438 ALA n 
1 439 GLY n 
1 440 ARG n 
1 441 MET n 
1 442 HIS n 
1 443 ALA n 
1 444 ALA n 
1 445 VAL n 
1 446 HIS n 
1 447 LYS n 
1 448 ASP n 
1 449 LEU n 
1 450 VAL n 
1 451 PHE n 
1 452 ILE n 
1 453 VAL n 
1 454 ALA n 
1 455 GLU n 
1 456 GLY n 
1 457 ASP n 
1 458 SER n 
1 459 LEU n 
1 460 VAL n 
1 461 CYS n 
1 462 TYR n 
1 463 ASN n 
1 464 PRO n 
1 465 LEU n 
1 466 LEU n 
1 467 ASP n 
1 468 SER n 
1 469 PHE n 
1 470 THR n 
1 471 ARG n 
1 472 LEU n 
1 473 CYS n 
1 474 LEU n 
1 475 PRO n 
1 476 GLU n 
1 477 ALA n 
1 478 TRP n 
1 479 SER n 
1 480 SER n 
1 481 ALA n 
1 482 PRO n 
1 483 SER n 
1 484 LEU n 
1 485 TRP n 
1 486 LYS n 
1 487 ILE n 
1 488 ALA n 
1 489 SER n 
1 490 CYS n 
1 491 ASN n 
1 492 GLY n 
1 493 SER n 
1 494 ILE n 
1 495 TYR n 
1 496 VAL n 
1 497 PHE n 
1 498 ARG n 
1 499 ASP n 
1 500 ARG n 
1 501 TYR n 
1 502 LYS n 
1 503 LYS n 
1 504 GLY n 
1 505 ASP n 
1 506 ALA n 
1 507 ASN n 
1 508 THR n 
1 509 TYR n 
1 510 LYS n 
1 511 LEU n 
1 512 ASP n 
1 513 PRO n 
1 514 ALA n 
1 515 THR n 
1 516 SER n 
1 517 ALA n 
1 518 VAL n 
1 519 THR n 
1 520 VAL n 
1 521 THR n 
1 522 ARG n 
1 523 GLY n 
1 524 ILE n 
1 525 LYS n 
1 526 VAL n 
1 527 LEU n 
1 528 LEU n 
1 529 THR n 
1 530 ASN n 
1 531 LEU n 
1 532 GLN n 
1 533 PHE n 
1 534 VAL n 
1 535 LEU n 
1 536 ALA n 
2 1   MET n 
2 2   ALA n 
2 3   GLN n 
2 4   THR n 
2 5   GLN n 
2 6   GLY n 
2 7   THR n 
2 8   ARG n 
2 9   ARG n 
2 10  LYS n 
2 11  VAL n 
2 12  CYS n 
2 13  TYR n 
2 14  TYR n 
2 15  TYR n 
2 16  ASP n 
2 17  GLY n 
2 18  ASP n 
2 19  VAL n 
2 20  GLY n 
2 21  ASN n 
2 22  TYR n 
2 23  TYR n 
2 24  TYR n 
2 25  GLY n 
2 26  GLN n 
2 27  GLY n 
2 28  HIS n 
2 29  PRO n 
2 30  MET n 
2 31  LYS n 
2 32  PRO n 
2 33  HIS n 
2 34  ARG n 
2 35  ILE n 
2 36  ARG n 
2 37  MET n 
2 38  THR n 
2 39  HIS n 
2 40  ASN n 
2 41  LEU n 
2 42  LEU n 
2 43  LEU n 
2 44  ASN n 
2 45  TYR n 
2 46  GLY n 
2 47  LEU n 
2 48  TYR n 
2 49  ARG n 
2 50  LYS n 
2 51  MET n 
2 52  GLU n 
2 53  ILE n 
2 54  TYR n 
2 55  ARG n 
2 56  PRO n 
2 57  HIS n 
2 58  LYS n 
2 59  ALA n 
2 60  ASN n 
2 61  ALA n 
2 62  GLU n 
2 63  GLU n 
2 64  MET n 
2 65  THR n 
2 66  LYS n 
2 67  TYR n 
2 68  HIS n 
2 69  SER n 
2 70  ASP n 
2 71  ASP n 
2 72  TYR n 
2 73  ILE n 
2 74  LYS n 
2 75  PHE n 
2 76  LEU n 
2 77  ARG n 
2 78  SER n 
2 79  ILE n 
2 80  ARG n 
2 81  PRO n 
2 82  ASP n 
2 83  ASN n 
2 84  MET n 
2 85  SER n 
2 86  GLU n 
2 87  TYR n 
2 88  SER n 
2 89  LYS n 
2 90  GLN n 
2 91  MET n 
2 92  GLN n 
2 93  ARG n 
2 94  PHE n 
2 95  ASN n 
2 96  VAL n 
2 97  GLY n 
2 98  GLU n 
2 99  ASP n 
2 100 CYS n 
2 101 PRO n 
2 102 VAL n 
2 103 PHE n 
2 104 ASP n 
2 105 GLY n 
2 106 LEU n 
2 107 PHE n 
2 108 GLU n 
2 109 PHE n 
2 110 CYS n 
2 111 GLN n 
2 112 LEU n 
2 113 SER n 
2 114 THR n 
2 115 GLY n 
2 116 GLY n 
2 117 SER n 
2 118 VAL n 
2 119 ALA n 
2 120 SER n 
2 121 ALA n 
2 122 VAL n 
2 123 LYS n 
2 124 LEU n 
2 125 ASN n 
2 126 LYS n 
2 127 GLN n 
2 128 GLN n 
2 129 THR n 
2 130 ASP n 
2 131 ILE n 
2 132 ALA n 
2 133 VAL n 
2 134 ASN n 
2 135 TRP n 
2 136 ALA n 
2 137 GLY n 
2 138 GLY n 
2 139 LEU n 
2 140 HIS n 
2 141 HIS n 
2 142 ALA n 
2 143 LYS n 
2 144 LYS n 
2 145 SER n 
2 146 GLU n 
2 147 ALA n 
2 148 SER n 
2 149 GLY n 
2 150 PHE n 
2 151 CYS n 
2 152 TYR n 
2 153 VAL n 
2 154 ASN n 
2 155 ASP n 
2 156 ILE n 
2 157 VAL n 
2 158 LEU n 
2 159 ALA n 
2 160 ILE n 
2 161 LEU n 
2 162 GLU n 
2 163 LEU n 
2 164 LEU n 
2 165 LYS n 
2 166 TYR n 
2 167 HIS n 
2 168 GLN n 
2 169 ARG n 
2 170 VAL n 
2 171 LEU n 
2 172 TYR n 
2 173 ILE n 
2 174 ASP n 
2 175 ILE n 
2 176 ASP n 
2 177 ILE n 
2 178 HIS n 
2 179 HIS n 
2 180 GLY n 
2 181 ASP n 
2 182 GLY n 
2 183 VAL n 
2 184 GLU n 
2 185 GLU n 
2 186 ALA n 
2 187 PHE n 
2 188 TYR n 
2 189 THR n 
2 190 THR n 
2 191 ASP n 
2 192 ARG n 
2 193 VAL n 
2 194 MET n 
2 195 THR n 
2 196 VAL n 
2 197 SER n 
2 198 PHE n 
2 199 HIS n 
2 200 LYS n 
2 201 TYR n 
2 202 GLY n 
2 203 GLU n 
2 204 TYR n 
2 205 PHE n 
2 206 PRO n 
2 207 GLY n 
2 208 THR n 
2 209 GLY n 
2 210 ASP n 
2 211 LEU n 
2 212 ARG n 
2 213 ASP n 
2 214 ILE n 
2 215 GLY n 
2 216 ALA n 
2 217 GLY n 
2 218 LYS n 
2 219 GLY n 
2 220 LYS n 
2 221 TYR n 
2 222 TYR n 
2 223 ALA n 
2 224 VAL n 
2 225 ASN n 
2 226 TYR n 
2 227 PRO n 
2 228 LEU n 
2 229 ARG n 
2 230 ASP n 
2 231 GLY n 
2 232 ILE n 
2 233 ASP n 
2 234 ASP n 
2 235 GLU n 
2 236 SER n 
2 237 TYR n 
2 238 GLU n 
2 239 ALA n 
2 240 ILE n 
2 241 PHE n 
2 242 LYS n 
2 243 PRO n 
2 244 VAL n 
2 245 MET n 
2 246 SER n 
2 247 LYS n 
2 248 VAL n 
2 249 MET n 
2 250 GLU n 
2 251 MET n 
2 252 PHE n 
2 253 GLN n 
2 254 PRO n 
2 255 SER n 
2 256 ALA n 
2 257 VAL n 
2 258 VAL n 
2 259 LEU n 
2 260 GLN n 
2 261 CYS n 
2 262 GLY n 
2 263 SER n 
2 264 ASP n 
2 265 SER n 
2 266 LEU n 
2 267 SER n 
2 268 GLY n 
2 269 ASP n 
2 270 ARG n 
2 271 LEU n 
2 272 GLY n 
2 273 CYS n 
2 274 PHE n 
2 275 ASN n 
2 276 LEU n 
2 277 THR n 
2 278 ILE n 
2 279 LYS n 
2 280 GLY n 
2 281 HIS n 
2 282 ALA n 
2 283 LYS n 
2 284 CYS n 
2 285 VAL n 
2 286 GLU n 
2 287 PHE n 
2 288 VAL n 
2 289 LYS n 
2 290 SER n 
2 291 PHE n 
2 292 ASN n 
2 293 LEU n 
2 294 PRO n 
2 295 MET n 
2 296 LEU n 
2 297 MET n 
2 298 LEU n 
2 299 GLY n 
2 300 GLY n 
2 301 GLY n 
2 302 GLY n 
2 303 TYR n 
2 304 THR n 
2 305 ILE n 
2 306 ARG n 
2 307 ASN n 
2 308 VAL n 
2 309 ALA n 
2 310 ARG n 
2 311 CYS n 
2 312 TRP n 
2 313 THR n 
2 314 TYR n 
2 315 GLU n 
2 316 THR n 
2 317 ALA n 
2 318 VAL n 
2 319 ALA n 
2 320 LEU n 
2 321 ASP n 
2 322 THR n 
2 323 GLU n 
2 324 ILE n 
2 325 PRO n 
2 326 ASN n 
2 327 GLU n 
2 328 LEU n 
2 329 PRO n 
2 330 TYR n 
2 331 ASN n 
2 332 ASP n 
2 333 TYR n 
2 334 PHE n 
2 335 GLU n 
2 336 TYR n 
2 337 PHE n 
2 338 GLY n 
2 339 PRO n 
2 340 ASP n 
2 341 PHE n 
2 342 LYS n 
2 343 LEU n 
2 344 HIS n 
2 345 ILE n 
2 346 SER n 
2 347 PRO n 
2 348 SER n 
2 349 ASN n 
2 350 MET n 
2 351 THR n 
2 352 ASN n 
2 353 GLN n 
2 354 ASN n 
2 355 THR n 
2 356 ASN n 
2 357 GLU n 
2 358 TYR n 
2 359 LEU n 
2 360 GLU n 
2 361 LYS n 
2 362 ILE n 
2 363 LYS n 
2 364 GLN n 
2 365 ARG n 
2 366 LEU n 
2 367 PHE n 
2 368 GLU n 
2 369 ASN n 
2 370 LEU n 
2 371 ARG n 
2 372 MET n 
2 373 LEU n 
2 374 PRO n 
2 375 HIS n 
2 376 ALA n 
2 377 PRO n 
2 378 GLY n 
2 379 VAL n 
2 380 GLN n 
2 381 MET n 
2 382 GLN n 
2 383 ALA n 
2 384 ILE n 
2 385 PRO n 
2 386 GLU n 
2 387 ASP n 
2 388 ALA n 
2 389 ILE n 
2 390 PRO n 
2 391 GLU n 
2 392 GLU n 
2 393 SER n 
2 394 GLY n 
2 395 ASP n 
2 396 GLU n 
2 397 ASP n 
2 398 GLU n 
2 399 ASP n 
2 400 ASP n 
2 401 PRO n 
2 402 ASP n 
2 403 LYS n 
2 404 ARG n 
2 405 ILE n 
2 406 SER n 
2 407 ILE n 
2 408 CYS n 
2 409 SER n 
2 410 SER n 
2 411 ASP n 
2 412 LYS n 
2 413 ARG n 
2 414 ILE n 
2 415 ALA n 
2 416 CYS n 
2 417 GLU n 
2 418 GLU n 
2 419 GLU n 
2 420 PHE n 
2 421 SER n 
2 422 ASP n 
2 423 SER n 
2 424 GLU n 
2 425 GLU n 
2 426 GLU n 
2 427 GLY n 
2 428 GLU n 
2 429 GLY n 
2 430 GLY n 
2 431 ARG n 
2 432 LYS n 
2 433 ASN n 
2 434 SER n 
2 435 SER n 
2 436 ASN n 
2 437 PHE n 
2 438 LYS n 
2 439 LYS n 
2 440 ALA n 
2 441 LYS n 
2 442 ARG n 
2 443 VAL n 
2 444 LYS n 
2 445 THR n 
2 446 GLU n 
2 447 ASP n 
2 448 GLU n 
2 449 LYS n 
2 450 GLU n 
2 451 LYS n 
2 452 ASP n 
2 453 PRO n 
2 454 GLU n 
2 455 GLU n 
2 456 LYS n 
2 457 LYS n 
2 458 GLU n 
2 459 VAL n 
2 460 THR n 
2 461 GLU n 
2 462 GLU n 
2 463 GLU n 
2 464 LYS n 
2 465 THR n 
2 466 LYS n 
2 467 GLU n 
2 468 GLU n 
2 469 LYS n 
2 470 PRO n 
2 471 GLU n 
2 472 ALA n 
2 473 LYS n 
2 474 GLY n 
2 475 VAL n 
2 476 LYS n 
2 477 GLU n 
2 478 GLU n 
2 479 VAL n 
2 480 LYS n 
2 481 LEU n 
2 482 ALA n 
3 1   MET n 
3 2   PRO n 
3 3   ALA n 
3 4   MET n 
3 5   VAL n 
3 6   GLU n 
3 7   LYS n 
3 8   GLY n 
3 9   PRO n 
3 10  GLU n 
3 11  VAL n 
3 12  SER n 
3 13  GLY n 
3 14  LYS n 
3 15  ARG n 
3 16  ARG n 
3 17  GLY n 
3 18  ARG n 
3 19  ASN n 
3 20  ASN n 
3 21  ALA n 
3 22  ALA n 
3 23  ALA n 
3 24  SER n 
3 25  ALA n 
3 26  SER n 
3 27  ALA n 
3 28  ALA n 
3 29  ALA n 
3 30  ALA n 
3 31  SER n 
3 32  ALA n 
3 33  ALA n 
3 34  ALA n 
3 35  SER n 
3 36  ALA n 
3 37  ALA n 
3 38  CYS n 
3 39  ALA n 
3 40  SER n 
3 41  PRO n 
3 42  ALA n 
3 43  ALA n 
3 44  THR n 
3 45  ALA n 
3 46  ALA n 
3 47  SER n 
3 48  GLY n 
3 49  ALA n 
3 50  ALA n 
3 51  ALA n 
3 52  SER n 
3 53  SER n 
3 54  ALA n 
3 55  SER n 
3 56  ALA n 
3 57  ALA n 
3 58  ALA n 
3 59  ALA n 
3 60  SER n 
3 61  ALA n 
3 62  ALA n 
3 63  ALA n 
3 64  ALA n 
3 65  PRO n 
3 66  ASN n 
3 67  ASN n 
3 68  GLY n 
3 69  GLN n 
3 70  ASN n 
3 71  LYS n 
3 72  SER n 
3 73  LEU n 
3 74  ALA n 
3 75  ALA n 
3 76  ALA n 
3 77  ALA n 
3 78  PRO n 
3 79  ASN n 
3 80  GLY n 
3 81  ASN n 
3 82  SER n 
3 83  SER n 
3 84  SER n 
3 85  ASN n 
3 86  SER n 
3 87  TRP n 
3 88  GLU n 
3 89  GLU n 
3 90  GLY n 
3 91  SER n 
3 92  SER n 
3 93  GLY n 
3 94  SER n 
3 95  SER n 
3 96  SER n 
3 97  ASP n 
3 98  GLU n 
3 99  GLU n 
3 100 HIS n 
3 101 GLY n 
3 102 GLY n 
3 103 GLY n 
3 104 GLY n 
3 105 MET n 
3 106 ARG n 
3 107 VAL n 
3 108 GLY n 
3 109 PRO n 
3 110 GLN n 
3 111 TYR n 
3 112 GLN n 
3 113 ALA n 
3 114 VAL n 
3 115 VAL n 
3 116 PRO n 
3 117 ASP n 
3 118 PHE n 
3 119 ASP n 
3 120 PRO n 
3 121 ALA n 
3 122 LYS n 
3 123 LEU n 
3 124 ALA n 
3 125 ARG n 
3 126 ARG n 
3 127 SER n 
3 128 GLN n 
3 129 GLU n 
3 130 ARG n 
3 131 ASP n 
3 132 ASN n 
3 133 LEU n 
3 134 GLY n 
3 135 MET n 
3 136 LEU n 
3 137 VAL n 
3 138 TRP n 
3 139 SER n 
3 140 PRO n 
3 141 ASN n 
3 142 GLN n 
3 143 ASN n 
3 144 LEU n 
3 145 SER n 
3 146 GLU n 
3 147 ALA n 
3 148 LYS n 
3 149 LEU n 
3 150 ASP n 
3 151 GLU n 
3 152 TYR n 
3 153 ILE n 
3 154 ALA n 
3 155 ILE n 
3 156 ALA n 
3 157 LYS n 
3 158 GLU n 
3 159 LYS n 
3 160 HIS n 
3 161 GLY n 
3 162 TYR n 
3 163 ASN n 
3 164 MET n 
3 165 GLU n 
3 166 GLN n 
3 167 ALA n 
3 168 LEU n 
3 169 GLY n 
3 170 MET n 
3 171 LEU n 
3 172 PHE n 
3 173 TRP n 
3 174 HIS n 
3 175 LYS n 
3 176 HIS n 
3 177 ASN n 
3 178 ILE n 
3 179 GLU n 
3 180 LYS n 
3 181 SER n 
3 182 LEU n 
3 183 ALA n 
3 184 ASP n 
3 185 LEU n 
3 186 PRO n 
3 187 ASN n 
3 188 PHE n 
3 189 THR n 
3 190 PRO n 
3 191 PHE n 
3 192 PRO n 
3 193 ASP n 
3 194 GLU n 
3 195 TRP n 
3 196 THR n 
3 197 VAL n 
3 198 GLU n 
3 199 ASP n 
3 200 LYS n 
3 201 VAL n 
3 202 LEU n 
3 203 PHE n 
3 204 GLU n 
3 205 GLN n 
3 206 ALA n 
3 207 PHE n 
3 208 SER n 
3 209 PHE n 
3 210 HIS n 
3 211 GLY n 
3 212 LYS n 
3 213 THR n 
3 214 PHE n 
3 215 HIS n 
3 216 ARG n 
3 217 ILE n 
3 218 GLN n 
3 219 GLN n 
3 220 MET n 
3 221 LEU n 
3 222 PRO n 
3 223 ASP n 
3 224 LYS n 
3 225 SER n 
3 226 ILE n 
3 227 ALA n 
3 228 SER n 
3 229 LEU n 
3 230 VAL n 
3 231 LYS n 
3 232 PHE n 
3 233 TYR n 
3 234 TYR n 
3 235 SER n 
3 236 TRP n 
3 237 LYS n 
3 238 LYS n 
3 239 THR n 
3 240 ARG n 
3 241 THR n 
3 242 LYS n 
3 243 THR n 
3 244 SER n 
3 245 VAL n 
3 246 MET n 
3 247 ASP n 
3 248 ARG n 
3 249 HIS n 
3 250 ALA n 
3 251 ARG n 
3 252 LYS n 
3 253 GLN n 
3 254 LYS n 
3 255 ARG n 
3 256 GLU n 
3 257 ARG n 
3 258 GLU n 
3 259 GLU n 
3 260 SER n 
3 261 GLU n 
3 262 ASP n 
3 263 GLU n 
3 264 LEU n 
3 265 GLU n 
3 266 GLU n 
3 267 ALA n 
3 268 ASN n 
3 269 GLY n 
3 270 ASN n 
3 271 ASN n 
3 272 PRO n 
3 273 ILE n 
3 274 ASP n 
3 275 ILE n 
3 276 GLU n 
3 277 VAL n 
3 278 ASP n 
3 279 GLN n 
3 280 ASN n 
3 281 LYS n 
3 282 GLU n 
3 283 SER n 
3 284 LYS n 
3 285 LYS n 
3 286 GLU n 
3 287 VAL n 
3 288 PRO n 
3 289 PRO n 
3 290 THR n 
3 291 GLU n 
3 292 THR n 
3 293 VAL n 
3 294 PRO n 
3 295 GLN n 
3 296 VAL n 
3 297 LYS n 
3 298 LYS n 
3 299 GLU n 
3 300 LYS n 
3 301 HIS n 
3 302 SER n 
3 303 THR n 
3 304 GLN n 
3 305 ALA n 
3 306 LYS n 
3 307 ASN n 
3 308 ARG n 
3 309 ALA n 
3 310 LYS n 
3 311 ARG n 
3 312 LYS n 
3 313 PRO n 
3 314 PRO n 
3 315 LYS n 
3 316 GLY n 
3 317 MET n 
3 318 PHE n 
3 319 LEU n 
3 320 SER n 
3 321 GLN n 
3 322 GLU n 
3 323 ASP n 
3 324 VAL n 
3 325 GLU n 
3 326 ALA n 
3 327 VAL n 
3 328 SER n 
3 329 ALA n 
3 330 ASN n 
3 331 ALA n 
3 332 THR n 
3 333 ALA n 
3 334 ALA n 
3 335 THR n 
3 336 THR n 
3 337 VAL n 
3 338 LEU n 
3 339 ARG n 
3 340 GLN n 
3 341 LEU n 
3 342 ASP n 
3 343 MET n 
3 344 GLU n 
3 345 LEU n 
3 346 VAL n 
3 347 SER n 
3 348 VAL n 
3 349 LYS n 
3 350 ARG n 
3 351 GLN n 
3 352 ILE n 
3 353 GLN n 
3 354 ASN n 
3 355 ILE n 
3 356 LYS n 
3 357 GLN n 
3 358 THR n 
3 359 ASN n 
3 360 SER n 
3 361 ALA n 
3 362 LEU n 
3 363 LYS n 
3 364 GLU n 
3 365 LYS n 
3 366 LEU n 
3 367 ASP n 
3 368 GLY n 
3 369 GLY n 
3 370 ILE n 
3 371 GLU n 
3 372 PRO n 
3 373 TYR n 
3 374 ARG n 
3 375 LEU n 
3 376 PRO n 
3 377 GLU n 
3 378 VAL n 
3 379 ILE n 
3 380 GLN n 
3 381 LYS n 
3 382 CYS n 
3 383 ASN n 
3 384 ALA n 
3 385 ARG n 
3 386 TRP n 
3 387 THR n 
3 388 THR n 
3 389 GLU n 
3 390 GLU n 
3 391 GLN n 
3 392 LEU n 
3 393 LEU n 
3 394 ALA n 
3 395 VAL n 
3 396 GLN n 
3 397 ALA n 
3 398 ILE n 
3 399 ARG n 
3 400 LYS n 
3 401 TYR n 
3 402 GLY n 
3 403 ARG n 
3 404 ASP n 
3 405 PHE n 
3 406 GLN n 
3 407 ALA n 
3 408 ILE n 
3 409 SER n 
3 410 ASP n 
3 411 VAL n 
3 412 ILE n 
3 413 GLY n 
3 414 ASN n 
3 415 LYS n 
3 416 SER n 
3 417 VAL n 
3 418 VAL n 
3 419 GLN n 
3 420 VAL n 
3 421 LYS n 
3 422 ASN n 
3 423 PHE n 
3 424 PHE n 
3 425 VAL n 
3 426 ASN n 
3 427 TYR n 
3 428 ARG n 
3 429 ARG n 
3 430 ARG n 
3 431 PHE n 
3 432 ASN n 
3 433 ILE n 
3 434 ASP n 
3 435 GLU n 
3 436 VAL n 
3 437 LEU n 
3 438 GLN n 
3 439 GLU n 
3 440 TRP n 
3 441 GLU n 
3 442 ALA n 
3 443 GLU n 
3 444 HIS n 
3 445 GLY n 
3 446 LYS n 
3 447 GLU n 
3 448 GLU n 
3 449 THR n 
3 450 ASN n 
3 451 GLY n 
3 452 PRO n 
3 453 SER n 
3 454 ASN n 
3 455 GLN n 
3 456 LYS n 
3 457 PRO n 
3 458 VAL n 
3 459 LYS n 
3 460 SER n 
3 461 PRO n 
3 462 ASP n 
3 463 ASN n 
3 464 SER n 
3 465 ILE n 
3 466 LYS n 
3 467 MET n 
3 468 PRO n 
3 469 GLU n 
3 470 GLU n 
3 471 GLU n 
3 472 ASP n 
3 473 GLU n 
3 474 ALA n 
3 475 PRO n 
3 476 VAL n 
3 477 LEU n 
3 478 ASP n 
3 479 VAL n 
3 480 ARG n 
3 481 TYR n 
3 482 ALA n 
3 483 SER n 
3 484 ALA n 
3 485 SER n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 536 human ? 'KBTBD4, BKLHD4'        ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Trichoplusia ni' 7111 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 482 human ? 'HDAC1, RPD3L1'         ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Homo sapiens'    9606 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
3 1 sample 'Biological sequence' 1 485 human ? 'RCOR1, KIAA0071, RCOR' ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Homo sapiens'    9606 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                     ?                                                                      
'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE                    ?                                                                      
'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE                  ?                                                                      
'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'             ?                                                                      
'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE                    ?                                                                      
'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE                   ?                                                                      
'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'             ?                                                                      
'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE                     ?                                                                      
'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE                   ?                                                                      
'C6 H10 N3 O2 1' 156.162 
IHP non-polymer         . 'INOSITOL HEXAKISPHOSPHATE' 'MYO-INOSITOL HEXAKISPHOSPHATE; INOSITOL 1,2,3,4,5,6-HEXAKISPHOSPHATE' 
'C6 H18 O24 P6'  660.035 
ILE 'L-peptide linking' y ISOLEUCINE                  ?                                                                      
'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE                     ?                                                                      
'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE                      ?                                                                      
'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE                  ?                                                                      
'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE               ?                                                                      
'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE                     ?                                                                      
'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE                      ?                                                                      
'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE                   ?                                                                      
'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                  ?                                                                      
'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE                    ?                                                                      
'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE                      ?                                                                      
'C5 H11 N O2'    117.146 
ZN  non-polymer         . 'ZINC ION'                  ?                                                                      
'Zn 2'           65.409  
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1    ?   ?   ?   A . n 
A 1 2   LYS 2   2    ?   ?   ?   A . n 
A 1 3   GLY 3   3    ?   ?   ?   A . n 
A 1 4   GLY 4   4    ?   ?   ?   A . n 
A 1 5   ASN 5   5    ?   ?   ?   A . n 
A 1 6   ALA 6   6    ?   ?   ?   A . n 
A 1 7   ASP 7   7    ?   ?   ?   A . n 
A 1 8   SER 8   8    ?   ?   ?   A . n 
A 1 9   TRP 9   9    ?   ?   ?   A . n 
A 1 10  GLN 10  10   ?   ?   ?   A . n 
A 1 11  ARG 11  11   ?   ?   ?   A . n 
A 1 12  GLU 12  12   ?   ?   ?   A . n 
A 1 13  LYS 13  13   ?   ?   ?   A . n 
A 1 14  LEU 14  14   ?   ?   ?   A . n 
A 1 15  ALA 15  15   ?   ?   ?   A . n 
A 1 16  SER 16  16   ?   ?   ?   A . n 
A 1 17  MET 17  17   ?   ?   ?   A . n 
A 1 18  GLU 18  18   ?   ?   ?   A . n 
A 1 19  SER 19  19   ?   ?   ?   A . n 
A 1 20  PRO 20  20   ?   ?   ?   A . n 
A 1 21  GLU 21  21   ?   ?   ?   A . n 
A 1 22  GLU 22  22   ?   ?   ?   A . n 
A 1 23  PRO 23  23   23  PRO PRO A . n 
A 1 24  GLY 24  24   24  GLY GLY A . n 
A 1 25  ALA 25  25   25  ALA ALA A . n 
A 1 26  SER 26  26   26  SER SER A . n 
A 1 27  MET 27  27   27  MET MET A . n 
A 1 28  ASP 28  28   28  ASP ASP A . n 
A 1 29  GLU 29  29   29  GLU GLU A . n 
A 1 30  ASN 30  30   30  ASN ASN A . n 
A 1 31  TYR 31  31   31  TYR TYR A . n 
A 1 32  PHE 32  32   32  PHE PHE A . n 
A 1 33  VAL 33  33   33  VAL VAL A . n 
A 1 34  ASN 34  34   34  ASN ASN A . n 
A 1 35  TYR 35  35   35  TYR TYR A . n 
A 1 36  THR 36  36   36  THR THR A . n 
A 1 37  PHE 37  37   37  PHE PHE A . n 
A 1 38  LYS 38  38   38  LYS LYS A . n 
A 1 39  ASP 39  39   39  ASP ASP A . n 
A 1 40  ARG 40  40   40  ARG ARG A . n 
A 1 41  SER 41  41   41  SER SER A . n 
A 1 42  HIS 42  42   42  HIS HIS A . n 
A 1 43  SER 43  43   43  SER SER A . n 
A 1 44  GLY 44  44   44  GLY GLY A . n 
A 1 45  ARG 45  45   45  ARG ARG A . n 
A 1 46  VAL 46  46   46  VAL VAL A . n 
A 1 47  ALA 47  47   47  ALA ALA A . n 
A 1 48  GLN 48  48   48  GLN GLN A . n 
A 1 49  GLY 49  49   49  GLY GLY A . n 
A 1 50  ILE 50  50   50  ILE ILE A . n 
A 1 51  MET 51  51   51  MET MET A . n 
A 1 52  LYS 52  52   52  LYS LYS A . n 
A 1 53  LEU 53  53   53  LEU LEU A . n 
A 1 54  CYS 54  54   54  CYS CYS A . n 
A 1 55  LEU 55  55   55  LEU LEU A . n 
A 1 56  GLU 56  56   56  GLU GLU A . n 
A 1 57  GLU 57  57   57  GLU GLU A . n 
A 1 58  GLU 58  58   58  GLU GLU A . n 
A 1 59  LEU 59  59   59  LEU LEU A . n 
A 1 60  PHE 60  60   60  PHE PHE A . n 
A 1 61  ALA 61  61   61  ALA ALA A . n 
A 1 62  ASP 62  62   62  ASP ASP A . n 
A 1 63  VAL 63  63   63  VAL VAL A . n 
A 1 64  THR 64  64   64  THR THR A . n 
A 1 65  ILE 65  65   65  ILE ILE A . n 
A 1 66  SER 66  66   66  SER SER A . n 
A 1 67  VAL 67  67   67  VAL VAL A . n 
A 1 68  GLU 68  68   68  GLU GLU A . n 
A 1 69  GLY 69  69   69  GLY GLY A . n 
A 1 70  ARG 70  70   70  ARG ARG A . n 
A 1 71  GLU 71  71   71  GLU GLU A . n 
A 1 72  PHE 72  72   72  PHE PHE A . n 
A 1 73  GLN 73  73   73  GLN GLN A . n 
A 1 74  LEU 74  74   74  LEU LEU A . n 
A 1 75  HIS 75  75   75  HIS HIS A . n 
A 1 76  ARG 76  76   76  ARG ARG A . n 
A 1 77  LEU 77  77   77  LEU LEU A . n 
A 1 78  VAL 78  78   78  VAL VAL A . n 
A 1 79  LEU 79  79   79  LEU LEU A . n 
A 1 80  SER 80  80   80  SER SER A . n 
A 1 81  ALA 81  81   81  ALA ALA A . n 
A 1 82  GLN 82  82   82  GLN GLN A . n 
A 1 83  SER 83  83   83  SER SER A . n 
A 1 84  CYS 84  84   84  CYS CYS A . n 
A 1 85  PHE 85  85   85  PHE PHE A . n 
A 1 86  PHE 86  86   86  PHE PHE A . n 
A 1 87  ARG 87  87   87  ARG ARG A . n 
A 1 88  SER 88  88   88  SER SER A . n 
A 1 89  MET 89  89   89  MET MET A . n 
A 1 90  PHE 90  90   90  PHE PHE A . n 
A 1 91  THR 91  91   91  THR THR A . n 
A 1 92  SER 92  92   92  SER SER A . n 
A 1 93  ASN 93  93   93  ASN ASN A . n 
A 1 94  LEU 94  94   ?   ?   ?   A . n 
A 1 95  LYS 95  95   ?   ?   ?   A . n 
A 1 96  GLU 96  96   ?   ?   ?   A . n 
A 1 97  ALA 97  97   ?   ?   ?   A . n 
A 1 98  HIS 98  98   ?   ?   ?   A . n 
A 1 99  ASN 99  99   99  ASN ASN A . n 
A 1 100 ARG 100 100  100 ARG ARG A . n 
A 1 101 VAL 101 101  101 VAL VAL A . n 
A 1 102 ILE 102 102  102 ILE ILE A . n 
A 1 103 VAL 103 103  103 VAL VAL A . n 
A 1 104 LEU 104 104  104 LEU LEU A . n 
A 1 105 GLN 105 105  105 GLN GLN A . n 
A 1 106 ASP 106 106  106 ASP ASP A . n 
A 1 107 VAL 107 107  107 VAL VAL A . n 
A 1 108 SER 108 108  108 SER SER A . n 
A 1 109 GLU 109 109  109 GLU GLU A . n 
A 1 110 SER 110 110  110 SER SER A . n 
A 1 111 VAL 111 111  111 VAL VAL A . n 
A 1 112 PHE 112 112  112 PHE PHE A . n 
A 1 113 GLN 113 113  113 GLN GLN A . n 
A 1 114 LEU 114 114  114 LEU LEU A . n 
A 1 115 LEU 115 115  115 LEU LEU A . n 
A 1 116 VAL 116 116  116 VAL VAL A . n 
A 1 117 ASP 117 117  117 ASP ASP A . n 
A 1 118 TYR 118 118  118 TYR TYR A . n 
A 1 119 ILE 119 119  119 ILE ILE A . n 
A 1 120 TYR 120 120  120 TYR TYR A . n 
A 1 121 HIS 121 121  121 HIS HIS A . n 
A 1 122 GLY 122 122  122 GLY GLY A . n 
A 1 123 THR 123 123  123 THR THR A . n 
A 1 124 VAL 124 124  124 VAL VAL A . n 
A 1 125 LYS 125 125  125 LYS LYS A . n 
A 1 126 LEU 126 126  126 LEU LEU A . n 
A 1 127 ARG 127 127  127 ARG ARG A . n 
A 1 128 ALA 128 128  128 ALA ALA A . n 
A 1 129 GLU 129 129  129 GLU GLU A . n 
A 1 130 GLU 130 130  130 GLU GLU A . n 
A 1 131 LEU 131 131  131 LEU LEU A . n 
A 1 132 GLN 132 132  132 GLN GLN A . n 
A 1 133 GLU 133 133  133 GLU GLU A . n 
A 1 134 ILE 134 134  134 ILE ILE A . n 
A 1 135 TYR 135 135  135 TYR TYR A . n 
A 1 136 GLU 136 136  136 GLU GLU A . n 
A 1 137 VAL 137 137  137 VAL VAL A . n 
A 1 138 SER 138 138  138 SER SER A . n 
A 1 139 ASP 139 139  139 ASP ASP A . n 
A 1 140 MET 140 140  140 MET MET A . n 
A 1 141 TYR 141 141  141 TYR TYR A . n 
A 1 142 GLN 142 142  142 GLN GLN A . n 
A 1 143 LEU 143 143  143 LEU LEU A . n 
A 1 144 THR 144 144  144 THR THR A . n 
A 1 145 SER 145 145  145 SER SER A . n 
A 1 146 LEU 146 146  146 LEU LEU A . n 
A 1 147 PHE 147 147  147 PHE PHE A . n 
A 1 148 GLU 148 148  148 GLU GLU A . n 
A 1 149 GLU 149 149  149 GLU GLU A . n 
A 1 150 CYS 150 150  150 CYS CYS A . n 
A 1 151 SER 151 151  151 SER SER A . n 
A 1 152 ARG 152 152  152 ARG ARG A . n 
A 1 153 PHE 153 153  153 PHE PHE A . n 
A 1 154 LEU 154 154  154 LEU LEU A . n 
A 1 155 ALA 155 155  155 ALA ALA A . n 
A 1 156 ARG 156 156  156 ARG ARG A . n 
A 1 157 THR 157 157  157 THR THR A . n 
A 1 158 VAL 158 158  158 VAL VAL A . n 
A 1 159 GLN 159 159  159 GLN GLN A . n 
A 1 160 VAL 160 160  160 VAL VAL A . n 
A 1 161 GLY 161 161  161 GLY GLY A . n 
A 1 162 ASN 162 162  162 ASN ASN A . n 
A 1 163 CYS 163 163  163 CYS CYS A . n 
A 1 164 LEU 164 164  164 LEU LEU A . n 
A 1 165 GLN 165 165  165 GLN GLN A . n 
A 1 166 VAL 166 166  166 VAL VAL A . n 
A 1 167 MET 167 167  167 MET MET A . n 
A 1 168 TRP 168 168  168 TRP TRP A . n 
A 1 169 LEU 169 169  169 LEU LEU A . n 
A 1 170 ALA 170 170  170 ALA ALA A . n 
A 1 171 ASP 171 171  171 ASP ASP A . n 
A 1 172 ARG 172 172  172 ARG ARG A . n 
A 1 173 HIS 173 173  173 HIS HIS A . n 
A 1 174 SER 174 174  174 SER SER A . n 
A 1 175 ASP 175 175  175 ASP ASP A . n 
A 1 176 PRO 176 176  176 PRO PRO A . n 
A 1 177 GLU 177 177  177 GLU GLU A . n 
A 1 178 LEU 178 178  178 LEU LEU A . n 
A 1 179 TYR 179 179  179 TYR TYR A . n 
A 1 180 THR 180 180  180 THR THR A . n 
A 1 181 ALA 181 181  181 ALA ALA A . n 
A 1 182 ALA 182 182  182 ALA ALA A . n 
A 1 183 LYS 183 183  183 LYS LYS A . n 
A 1 184 HIS 184 184  184 HIS HIS A . n 
A 1 185 CYS 185 185  185 CYS CYS A . n 
A 1 186 ALA 186 186  186 ALA ALA A . n 
A 1 187 LYS 187 187  187 LYS LYS A . n 
A 1 188 THR 188 188  188 THR THR A . n 
A 1 189 HIS 189 189  189 HIS HIS A . n 
A 1 190 LEU 190 190  190 LEU LEU A . n 
A 1 191 ALA 191 191  191 ALA ALA A . n 
A 1 192 GLN 192 192  192 GLN GLN A . n 
A 1 193 LEU 193 193  193 LEU LEU A . n 
A 1 194 GLN 194 194  194 GLN GLN A . n 
A 1 195 ASN 195 195  195 ASN ASN A . n 
A 1 196 THR 196 196  196 THR THR A . n 
A 1 197 GLU 197 197  197 GLU GLU A . n 
A 1 198 GLU 198 198  198 GLU GLU A . n 
A 1 199 PHE 199 199  199 PHE PHE A . n 
A 1 200 LEU 200 200  200 LEU LEU A . n 
A 1 201 HIS 201 201  201 HIS HIS A . n 
A 1 202 LEU 202 202  202 LEU LEU A . n 
A 1 203 PRO 203 203  203 PRO PRO A . n 
A 1 204 HIS 204 204  204 HIS HIS A . n 
A 1 205 ARG 205 205  205 ARG ARG A . n 
A 1 206 LEU 206 206  206 LEU LEU A . n 
A 1 207 LEU 207 207  207 LEU LEU A . n 
A 1 208 THR 208 208  208 THR THR A . n 
A 1 209 ASP 209 209  209 ASP ASP A . n 
A 1 210 ILE 210 210  210 ILE ILE A . n 
A 1 211 ILE 211 211  211 ILE ILE A . n 
A 1 212 SER 212 212  212 SER SER A . n 
A 1 213 ASP 213 213  213 ASP ASP A . n 
A 1 214 GLY 214 214  214 GLY GLY A . n 
A 1 215 VAL 215 215  215 VAL VAL A . n 
A 1 216 PRO 216 216  216 PRO PRO A . n 
A 1 217 CYS 217 217  217 CYS CYS A . n 
A 1 218 SER 218 218  218 SER SER A . n 
A 1 219 GLN 219 219  219 GLN GLN A . n 
A 1 220 ASN 220 220  220 ASN ASN A . n 
A 1 221 PRO 221 221  221 PRO PRO A . n 
A 1 222 THR 222 222  222 THR THR A . n 
A 1 223 GLU 223 223  223 GLU GLU A . n 
A 1 224 ALA 224 224  224 ALA ALA A . n 
A 1 225 ILE 225 225  225 ILE ILE A . n 
A 1 226 GLU 226 226  226 GLU GLU A . n 
A 1 227 ALA 227 227  227 ALA ALA A . n 
A 1 228 TRP 228 228  228 TRP TRP A . n 
A 1 229 ILE 229 229  229 ILE ILE A . n 
A 1 230 ASN 230 230  230 ASN ASN A . n 
A 1 231 PHE 231 231  231 PHE PHE A . n 
A 1 232 ASN 232 232  232 ASN ASN A . n 
A 1 233 LYS 233 233  233 LYS LYS A . n 
A 1 234 GLU 234 234  234 GLU GLU A . n 
A 1 235 GLU 235 235  235 GLU GLU A . n 
A 1 236 ARG 236 236  236 ARG ARG A . n 
A 1 237 GLU 237 237  237 GLU GLU A . n 
A 1 238 ALA 238 238  238 ALA ALA A . n 
A 1 239 PHE 239 239  239 PHE PHE A . n 
A 1 240 ALA 240 240  240 ALA ALA A . n 
A 1 241 GLU 241 241  241 GLU GLU A . n 
A 1 242 SER 242 242  242 SER SER A . n 
A 1 243 LEU 243 243  243 LEU LEU A . n 
A 1 244 ARG 244 244  244 ARG ARG A . n 
A 1 245 THR 245 245  245 THR THR A . n 
A 1 246 SER 246 246  246 SER SER A . n 
A 1 247 LEU 247 247  247 LEU LEU A . n 
A 1 248 LYS 248 248  248 LYS LYS A . n 
A 1 249 GLU 249 249  249 GLU GLU A . n 
A 1 250 ILE 250 250  250 ILE ILE A . n 
A 1 251 GLY 251 251  251 GLY GLY A . n 
A 1 252 GLU 252 252  252 GLU GLU A . n 
A 1 253 ASN 253 253  253 ASN ASN A . n 
A 1 254 VAL 254 254  254 VAL VAL A . n 
A 1 255 HIS 255 255  255 HIS HIS A . n 
A 1 256 ILE 256 256  256 ILE ILE A . n 
A 1 257 TYR 257 257  257 TYR TYR A . n 
A 1 258 LEU 258 258  258 LEU LEU A . n 
A 1 259 ILE 259 259  259 ILE ILE A . n 
A 1 260 GLY 260 260  260 GLY GLY A . n 
A 1 261 LYS 261 261  261 LYS LYS A . n 
A 1 262 GLU 262 262  262 GLU GLU A . n 
A 1 263 SER 263 263  263 SER SER A . n 
A 1 264 SER 264 264  264 SER SER A . n 
A 1 265 ARG 265 265  265 ARG ARG A . n 
A 1 266 THR 266 266  266 THR THR A . n 
A 1 267 HIS 267 267  267 HIS HIS A . n 
A 1 268 SER 268 268  268 SER SER A . n 
A 1 269 LEU 269 269  269 LEU LEU A . n 
A 1 270 ALA 270 270  270 ALA ALA A . n 
A 1 271 VAL 271 271  271 VAL VAL A . n 
A 1 272 SER 272 272  272 SER SER A . n 
A 1 273 LEU 273 273  273 LEU LEU A . n 
A 1 274 HIS 274 274  274 HIS HIS A . n 
A 1 275 CYS 275 275  275 CYS CYS A . n 
A 1 276 ALA 276 276  276 ALA ALA A . n 
A 1 277 GLU 277 277  277 GLU GLU A . n 
A 1 278 ASP 278 278  278 ASP ASP A . n 
A 1 279 ASP 279 279  279 ASP ASP A . n 
A 1 280 SER 280 280  280 SER SER A . n 
A 1 281 ILE 281 281  281 ILE ILE A . n 
A 1 282 SER 282 282  282 SER SER A . n 
A 1 283 VAL 283 283  283 VAL VAL A . n 
A 1 284 SER 284 284  284 SER SER A . n 
A 1 285 GLY 285 285  285 GLY GLY A . n 
A 1 286 GLN 286 286  286 GLN GLN A . n 
A 1 287 ASN 287 287  287 ASN ASN A . n 
A 1 288 SER 288 288  288 SER SER A . n 
A 1 289 LEU 289 289  289 LEU LEU A . n 
A 1 290 CYS 290 290  290 CYS CYS A . n 
A 1 291 HIS 291 291  291 HIS HIS A . n 
A 1 292 GLN 292 292  292 GLN GLN A . n 
A 1 293 ILE 293 293  293 ILE ILE A . n 
A 1 294 THR 294 294  294 THR THR A . n 
A 1 295 ALA 295 295  295 ALA ALA A . n 
A 1 296 ALA 296 296  296 ALA ALA A . n 
A 1 297 CYS 297 297  297 CYS CYS A . n 
A 1 298 LYS 298 298  298 LYS LYS A . n 
A 1 299 HIS 299 299  299 HIS HIS A . n 
A 1 300 GLY 300 300  300 GLY GLY A . n 
A 1 301 GLY 301 301  301 GLY GLY A . n 
A 1 302 ASP 302 302  302 ASP ASP A . n 
A 1 303 LEU 303 303  303 LEU LEU A . n 
A 1 304 TYR 304 304  304 TYR TYR A . n 
A 1 305 VAL 305 305  305 VAL VAL A . n 
A 1 306 VAL 306 306  306 VAL VAL A . n 
A 1 307 GLY 307 307  307 GLY GLY A . n 
A 1 308 GLY 308 308  ?   ?   ?   A . n 
A 1 309 SER 309 309  ?   ?   ?   A . n 
A 1 310 THR 310 310  ?   ?   ?   A . n 
A 1 311 THR 311 311  ?   ?   ?   A . n 
A 1 312 TYR 312 312  312 TYR TYR A . n 
A 1 313 MET 313 313  313 MET MET A . n 
A 1 314 LEU 314 314  314 LEU LEU A . n 
A 1 315 ARG 315 315  315 ARG ARG A . n 
A 1 316 MET 316 316  316 MET MET A . n 
A 1 317 TRP 317 317  317 TRP TRP A . n 
A 1 318 LYS 318 318  318 LYS LYS A . n 
A 1 319 CYS 319 319  319 CYS CYS A . n 
A 1 320 ASN 320 320  320 ASN ASN A . n 
A 1 321 ASN 321 321  321 ASN ASN A . n 
A 1 322 ALA 322 322  322 ALA ALA A . n 
A 1 323 THR 323 323  323 THR THR A . n 
A 1 324 VAL 324 324  324 VAL VAL A . n 
A 1 325 ASP 325 325  325 ASP ASP A . n 
A 1 326 TRP 326 326  326 TRP TRP A . n 
A 1 327 GLU 327 327  327 GLU GLU A . n 
A 1 328 TRP 328 328  328 TRP TRP A . n 
A 1 329 CYS 329 329  329 CYS CYS A . n 
A 1 330 ALA 330 330  330 ALA ALA A . n 
A 1 331 PRO 331 331  331 PRO PRO A . n 
A 1 332 LEU 332 332  332 LEU LEU A . n 
A 1 333 PRO 333 333  333 PRO PRO A . n 
A 1 334 ARG 334 334  334 ARG ARG A . n 
A 1 335 ASP 335 335  335 ASP ASP A . n 
A 1 336 ARG 336 336  336 ARG ARG A . n 
A 1 337 LEU 337 337  337 LEU LEU A . n 
A 1 338 GLN 338 338  338 GLN GLN A . n 
A 1 339 HIS 339 339  339 HIS HIS A . n 
A 1 340 THR 340 340  340 THR THR A . n 
A 1 341 LEU 341 341  341 LEU LEU A . n 
A 1 342 VAL 342 342  342 VAL VAL A . n 
A 1 343 SER 343 343  343 SER SER A . n 
A 1 344 VAL 344 344  344 VAL VAL A . n 
A 1 345 PRO 345 345  345 PRO PRO A . n 
A 1 346 GLY 346 346  346 GLY GLY A . n 
A 1 347 LYS 347 347  347 LYS LYS A . n 
A 1 348 ASP 348 348  348 ASP ASP A . n 
A 1 349 ALA 349 349  349 ALA ALA A . n 
A 1 350 ILE 350 350  350 ILE ILE A . n 
A 1 351 TYR 351 351  351 TYR TYR A . n 
A 1 352 SER 352 352  352 SER SER A . n 
A 1 353 LEU 353 353  353 LEU LEU A . n 
A 1 354 GLY 354 354  354 GLY GLY A . n 
A 1 355 GLY 355 355  355 GLY GLY A . n 
A 1 356 LYS 356 356  356 LYS LYS A . n 
A 1 357 THR 357 357  357 THR THR A . n 
A 1 358 LEU 358 358  358 LEU LEU A . n 
A 1 359 GLN 359 359  359 GLN GLN A . n 
A 1 360 ASP 360 360  360 ASP ASP A . n 
A 1 361 THR 361 361  361 THR THR A . n 
A 1 362 LEU 362 362  362 LEU LEU A . n 
A 1 363 SER 363 363  363 SER SER A . n 
A 1 364 ASN 364 364  364 ASN ASN A . n 
A 1 365 ALA 365 365  365 ALA ALA A . n 
A 1 366 VAL 366 366  366 VAL VAL A . n 
A 1 367 ILE 367 367  367 ILE ILE A . n 
A 1 368 TYR 368 368  368 TYR TYR A . n 
A 1 369 TYR 369 369  369 TYR TYR A . n 
A 1 370 ARG 370 370  370 ARG ARG A . n 
A 1 371 VAL 371 371  371 VAL VAL A . n 
A 1 372 GLY 372 372  372 GLY GLY A . n 
A 1 373 ASP 373 373  373 ASP ASP A . n 
A 1 374 ASN 374 374  374 ASN ASN A . n 
A 1 375 VAL 375 375  375 VAL VAL A . n 
A 1 376 TRP 376 376  376 TRP TRP A . n 
A 1 377 THR 377 377  377 THR THR A . n 
A 1 378 GLU 378 378  378 GLU GLU A . n 
A 1 379 THR 379 379  379 THR THR A . n 
A 1 380 THR 380 380  380 THR THR A . n 
A 1 381 GLN 381 381  381 GLN GLN A . n 
A 1 382 LEU 382 382  382 LEU LEU A . n 
A 1 383 GLU 383 383  383 GLU GLU A . n 
A 1 384 VAL 384 384  384 VAL VAL A . n 
A 1 385 ALA 385 385  385 ALA ALA A . n 
A 1 386 VAL 386 386  386 VAL VAL A . n 
A 1 387 SER 387 387  387 SER SER A . n 
A 1 388 GLY 388 388  388 GLY GLY A . n 
A 1 389 ALA 389 389  389 ALA ALA A . n 
A 1 390 ALA 390 390  390 ALA ALA A . n 
A 1 391 GLY 391 391  391 GLY GLY A . n 
A 1 392 ALA 392 392  392 ALA ALA A . n 
A 1 393 ASN 393 393  393 ASN ASN A . n 
A 1 394 LEU 394 394  394 LEU LEU A . n 
A 1 395 ASN 395 395  395 ASN ASN A . n 
A 1 396 GLY 396 396  396 GLY GLY A . n 
A 1 397 ILE 397 397  397 ILE ILE A . n 
A 1 398 ILE 398 398  398 ILE ILE A . n 
A 1 399 TYR 399 399  399 TYR TYR A . n 
A 1 400 LEU 400 400  400 LEU LEU A . n 
A 1 401 LEU 401 401  401 LEU LEU A . n 
A 1 402 GLY 402 402  402 GLY GLY A . n 
A 1 403 GLY 403 403  403 GLY GLY A . n 
A 1 404 GLU 404 404  404 GLU GLU A . n 
A 1 405 GLU 405 405  405 GLU GLU A . n 
A 1 406 ASN 406 406  406 ASN ASN A . n 
A 1 407 ASP 407 407  407 ASP ASP A . n 
A 1 408 LEU 408 408  408 LEU LEU A . n 
A 1 409 ASP 409 409  409 ASP ASP A . n 
A 1 410 PHE 410 410  410 PHE PHE A . n 
A 1 411 PHE 411 411  411 PHE PHE A . n 
A 1 412 THR 412 412  412 THR THR A . n 
A 1 413 LYS 413 413  413 LYS LYS A . n 
A 1 414 PRO 414 414  414 PRO PRO A . n 
A 1 415 SER 415 415  415 SER SER A . n 
A 1 416 ARG 416 416  416 ARG ARG A . n 
A 1 417 LEU 417 417  417 LEU LEU A . n 
A 1 418 ILE 418 418  418 ILE ILE A . n 
A 1 419 GLN 419 419  419 GLN GLN A . n 
A 1 420 CYS 420 420  420 CYS CYS A . n 
A 1 421 PHE 421 421  421 PHE PHE A . n 
A 1 422 ASP 422 422  422 ASP ASP A . n 
A 1 423 THR 423 423  423 THR THR A . n 
A 1 424 GLU 424 424  424 GLU GLU A . n 
A 1 425 THR 425 425  425 THR THR A . n 
A 1 426 ASP 426 426  426 ASP ASP A . n 
A 1 427 LYS 427 427  427 LYS LYS A . n 
A 1 428 CYS 428 428  428 CYS CYS A . n 
A 1 429 HIS 429 429  429 HIS HIS A . n 
A 1 430 VAL 430 430  430 VAL VAL A . n 
A 1 431 LYS 431 431  431 LYS LYS A . n 
A 1 432 PRO 432 432  432 PRO PRO A . n 
A 1 433 TYR 433 433  433 TYR TYR A . n 
A 1 434 VAL 434 434  434 VAL VAL A . n 
A 1 435 LEU 435 435  435 LEU LEU A . n 
A 1 436 PRO 436 436  436 PRO PRO A . n 
A 1 437 PHE 437 437  437 PHE PHE A . n 
A 1 438 ALA 438 438  438 ALA ALA A . n 
A 1 439 GLY 439 439  439 GLY GLY A . n 
A 1 440 ARG 440 440  440 ARG ARG A . n 
A 1 441 MET 441 441  441 MET MET A . n 
A 1 442 HIS 442 442  442 HIS HIS A . n 
A 1 443 ALA 443 443  443 ALA ALA A . n 
A 1 444 ALA 444 444  444 ALA ALA A . n 
A 1 445 VAL 445 445  445 VAL VAL A . n 
A 1 446 HIS 446 446  446 HIS HIS A . n 
A 1 447 LYS 447 447  447 LYS LYS A . n 
A 1 448 ASP 448 448  448 ASP ASP A . n 
A 1 449 LEU 449 449  449 LEU LEU A . n 
A 1 450 VAL 450 450  450 VAL VAL A . n 
A 1 451 PHE 451 451  451 PHE PHE A . n 
A 1 452 ILE 452 452  452 ILE ILE A . n 
A 1 453 VAL 453 453  453 VAL VAL A . n 
A 1 454 ALA 454 454  454 ALA ALA A . n 
A 1 455 GLU 455 455  455 GLU GLU A . n 
A 1 456 GLY 456 456  456 GLY GLY A . n 
A 1 457 ASP 457 457  457 ASP ASP A . n 
A 1 458 SER 458 458  458 SER SER A . n 
A 1 459 LEU 459 459  459 LEU LEU A . n 
A 1 460 VAL 460 460  460 VAL VAL A . n 
A 1 461 CYS 461 461  461 CYS CYS A . n 
A 1 462 TYR 462 462  462 TYR TYR A . n 
A 1 463 ASN 463 463  463 ASN ASN A . n 
A 1 464 PRO 464 464  464 PRO PRO A . n 
A 1 465 LEU 465 465  465 LEU LEU A . n 
A 1 466 LEU 466 466  466 LEU LEU A . n 
A 1 467 ASP 467 467  467 ASP ASP A . n 
A 1 468 SER 468 468  468 SER SER A . n 
A 1 469 PHE 469 469  469 PHE PHE A . n 
A 1 470 THR 470 470  470 THR THR A . n 
A 1 471 ARG 471 471  471 ARG ARG A . n 
A 1 472 LEU 472 472  472 LEU LEU A . n 
A 1 473 CYS 473 473  473 CYS CYS A . n 
A 1 474 LEU 474 474  474 LEU LEU A . n 
A 1 475 PRO 475 475  475 PRO PRO A . n 
A 1 476 GLU 476 476  476 GLU GLU A . n 
A 1 477 ALA 477 477  ?   ?   ?   A . n 
A 1 478 TRP 478 478  ?   ?   ?   A . n 
A 1 479 SER 479 479  ?   ?   ?   A . n 
A 1 480 SER 480 480  ?   ?   ?   A . n 
A 1 481 ALA 481 481  ?   ?   ?   A . n 
A 1 482 PRO 482 482  ?   ?   ?   A . n 
A 1 483 SER 483 483  483 SER SER A . n 
A 1 484 LEU 484 484  484 LEU LEU A . n 
A 1 485 TRP 485 485  485 TRP TRP A . n 
A 1 486 LYS 486 486  486 LYS LYS A . n 
A 1 487 ILE 487 487  487 ILE ILE A . n 
A 1 488 ALA 488 488  488 ALA ALA A . n 
A 1 489 SER 489 489  489 SER SER A . n 
A 1 490 CYS 490 490  490 CYS CYS A . n 
A 1 491 ASN 491 491  491 ASN ASN A . n 
A 1 492 GLY 492 492  492 GLY GLY A . n 
A 1 493 SER 493 493  493 SER SER A . n 
A 1 494 ILE 494 494  494 ILE ILE A . n 
A 1 495 TYR 495 495  495 TYR TYR A . n 
A 1 496 VAL 496 496  496 VAL VAL A . n 
A 1 497 PHE 497 497  497 PHE PHE A . n 
A 1 498 ARG 498 498  498 ARG ARG A . n 
A 1 499 ASP 499 499  499 ASP ASP A . n 
A 1 500 ARG 500 500  500 ARG ARG A . n 
A 1 501 TYR 501 501  501 TYR TYR A . n 
A 1 502 LYS 502 502  502 LYS LYS A . n 
A 1 503 LYS 503 503  503 LYS LYS A . n 
A 1 504 GLY 504 504  504 GLY GLY A . n 
A 1 505 ASP 505 505  505 ASP ASP A . n 
A 1 506 ALA 506 506  506 ALA ALA A . n 
A 1 507 ASN 507 507  507 ASN ASN A . n 
A 1 508 THR 508 508  508 THR THR A . n 
A 1 509 TYR 509 509  509 TYR TYR A . n 
A 1 510 LYS 510 510  510 LYS LYS A . n 
A 1 511 LEU 511 511  511 LEU LEU A . n 
A 1 512 ASP 512 512  512 ASP ASP A . n 
A 1 513 PRO 513 513  513 PRO PRO A . n 
A 1 514 ALA 514 514  514 ALA ALA A . n 
A 1 515 THR 515 515  515 THR THR A . n 
A 1 516 SER 516 516  516 SER SER A . n 
A 1 517 ALA 517 517  517 ALA ALA A . n 
A 1 518 VAL 518 518  518 VAL VAL A . n 
A 1 519 THR 519 519  519 THR THR A . n 
A 1 520 VAL 520 520  520 VAL VAL A . n 
A 1 521 THR 521 521  521 THR THR A . n 
A 1 522 ARG 522 522  522 ARG ARG A . n 
A 1 523 GLY 523 523  523 GLY GLY A . n 
A 1 524 ILE 524 524  524 ILE ILE A . n 
A 1 525 LYS 525 525  525 LYS LYS A . n 
A 1 526 VAL 526 526  526 VAL VAL A . n 
A 1 527 LEU 527 527  527 LEU LEU A . n 
A 1 528 LEU 528 528  528 LEU LEU A . n 
A 1 529 THR 529 529  529 THR THR A . n 
A 1 530 ASN 530 530  530 ASN ASN A . n 
A 1 531 LEU 531 531  531 LEU LEU A . n 
A 1 532 GLN 532 532  532 GLN GLN A . n 
A 1 533 PHE 533 533  533 PHE PHE A . n 
A 1 534 VAL 534 534  534 VAL VAL A . n 
A 1 535 LEU 535 535  535 LEU LEU A . n 
A 1 536 ALA 536 536  536 ALA ALA A . n 
B 1 1   MET 1   1    ?   ?   ?   B . n 
B 1 2   LYS 2   2    ?   ?   ?   B . n 
B 1 3   GLY 3   3    ?   ?   ?   B . n 
B 1 4   GLY 4   4    ?   ?   ?   B . n 
B 1 5   ASN 5   5    ?   ?   ?   B . n 
B 1 6   ALA 6   6    ?   ?   ?   B . n 
B 1 7   ASP 7   7    ?   ?   ?   B . n 
B 1 8   SER 8   8    ?   ?   ?   B . n 
B 1 9   TRP 9   9    ?   ?   ?   B . n 
B 1 10  GLN 10  10   ?   ?   ?   B . n 
B 1 11  ARG 11  11   ?   ?   ?   B . n 
B 1 12  GLU 12  12   ?   ?   ?   B . n 
B 1 13  LYS 13  13   ?   ?   ?   B . n 
B 1 14  LEU 14  14   ?   ?   ?   B . n 
B 1 15  ALA 15  15   ?   ?   ?   B . n 
B 1 16  SER 16  16   ?   ?   ?   B . n 
B 1 17  MET 17  17   ?   ?   ?   B . n 
B 1 18  GLU 18  18   ?   ?   ?   B . n 
B 1 19  SER 19  19   ?   ?   ?   B . n 
B 1 20  PRO 20  20   ?   ?   ?   B . n 
B 1 21  GLU 21  21   ?   ?   ?   B . n 
B 1 22  GLU 22  22   ?   ?   ?   B . n 
B 1 23  PRO 23  23   ?   ?   ?   B . n 
B 1 24  GLY 24  24   ?   ?   ?   B . n 
B 1 25  ALA 25  25   ?   ?   ?   B . n 
B 1 26  SER 26  26   26  SER SER B . n 
B 1 27  MET 27  27   27  MET MET B . n 
B 1 28  ASP 28  28   28  ASP ASP B . n 
B 1 29  GLU 29  29   29  GLU GLU B . n 
B 1 30  ASN 30  30   30  ASN ASN B . n 
B 1 31  TYR 31  31   31  TYR TYR B . n 
B 1 32  PHE 32  32   32  PHE PHE B . n 
B 1 33  VAL 33  33   33  VAL VAL B . n 
B 1 34  ASN 34  34   34  ASN ASN B . n 
B 1 35  TYR 35  35   35  TYR TYR B . n 
B 1 36  THR 36  36   36  THR THR B . n 
B 1 37  PHE 37  37   37  PHE PHE B . n 
B 1 38  LYS 38  38   38  LYS LYS B . n 
B 1 39  ASP 39  39   39  ASP ASP B . n 
B 1 40  ARG 40  40   40  ARG ARG B . n 
B 1 41  SER 41  41   41  SER SER B . n 
B 1 42  HIS 42  42   42  HIS HIS B . n 
B 1 43  SER 43  43   43  SER SER B . n 
B 1 44  GLY 44  44   44  GLY GLY B . n 
B 1 45  ARG 45  45   45  ARG ARG B . n 
B 1 46  VAL 46  46   46  VAL VAL B . n 
B 1 47  ALA 47  47   47  ALA ALA B . n 
B 1 48  GLN 48  48   48  GLN GLN B . n 
B 1 49  GLY 49  49   49  GLY GLY B . n 
B 1 50  ILE 50  50   50  ILE ILE B . n 
B 1 51  MET 51  51   51  MET MET B . n 
B 1 52  LYS 52  52   52  LYS LYS B . n 
B 1 53  LEU 53  53   53  LEU LEU B . n 
B 1 54  CYS 54  54   54  CYS CYS B . n 
B 1 55  LEU 55  55   55  LEU LEU B . n 
B 1 56  GLU 56  56   56  GLU GLU B . n 
B 1 57  GLU 57  57   57  GLU GLU B . n 
B 1 58  GLU 58  58   58  GLU GLU B . n 
B 1 59  LEU 59  59   59  LEU LEU B . n 
B 1 60  PHE 60  60   60  PHE PHE B . n 
B 1 61  ALA 61  61   61  ALA ALA B . n 
B 1 62  ASP 62  62   62  ASP ASP B . n 
B 1 63  VAL 63  63   63  VAL VAL B . n 
B 1 64  THR 64  64   64  THR THR B . n 
B 1 65  ILE 65  65   65  ILE ILE B . n 
B 1 66  SER 66  66   66  SER SER B . n 
B 1 67  VAL 67  67   67  VAL VAL B . n 
B 1 68  GLU 68  68   68  GLU GLU B . n 
B 1 69  GLY 69  69   69  GLY GLY B . n 
B 1 70  ARG 70  70   70  ARG ARG B . n 
B 1 71  GLU 71  71   71  GLU GLU B . n 
B 1 72  PHE 72  72   72  PHE PHE B . n 
B 1 73  GLN 73  73   73  GLN GLN B . n 
B 1 74  LEU 74  74   74  LEU LEU B . n 
B 1 75  HIS 75  75   75  HIS HIS B . n 
B 1 76  ARG 76  76   76  ARG ARG B . n 
B 1 77  LEU 77  77   77  LEU LEU B . n 
B 1 78  VAL 78  78   78  VAL VAL B . n 
B 1 79  LEU 79  79   79  LEU LEU B . n 
B 1 80  SER 80  80   80  SER SER B . n 
B 1 81  ALA 81  81   81  ALA ALA B . n 
B 1 82  GLN 82  82   82  GLN GLN B . n 
B 1 83  SER 83  83   83  SER SER B . n 
B 1 84  CYS 84  84   84  CYS CYS B . n 
B 1 85  PHE 85  85   85  PHE PHE B . n 
B 1 86  PHE 86  86   86  PHE PHE B . n 
B 1 87  ARG 87  87   87  ARG ARG B . n 
B 1 88  SER 88  88   88  SER SER B . n 
B 1 89  MET 89  89   89  MET MET B . n 
B 1 90  PHE 90  90   90  PHE PHE B . n 
B 1 91  THR 91  91   91  THR THR B . n 
B 1 92  SER 92  92   92  SER SER B . n 
B 1 93  ASN 93  93   93  ASN ASN B . n 
B 1 94  LEU 94  94   94  LEU LEU B . n 
B 1 95  LYS 95  95   95  LYS LYS B . n 
B 1 96  GLU 96  96   96  GLU GLU B . n 
B 1 97  ALA 97  97   97  ALA ALA B . n 
B 1 98  HIS 98  98   98  HIS HIS B . n 
B 1 99  ASN 99  99   99  ASN ASN B . n 
B 1 100 ARG 100 100  100 ARG ARG B . n 
B 1 101 VAL 101 101  101 VAL VAL B . n 
B 1 102 ILE 102 102  102 ILE ILE B . n 
B 1 103 VAL 103 103  103 VAL VAL B . n 
B 1 104 LEU 104 104  104 LEU LEU B . n 
B 1 105 GLN 105 105  105 GLN GLN B . n 
B 1 106 ASP 106 106  106 ASP ASP B . n 
B 1 107 VAL 107 107  107 VAL VAL B . n 
B 1 108 SER 108 108  108 SER SER B . n 
B 1 109 GLU 109 109  109 GLU GLU B . n 
B 1 110 SER 110 110  110 SER SER B . n 
B 1 111 VAL 111 111  111 VAL VAL B . n 
B 1 112 PHE 112 112  112 PHE PHE B . n 
B 1 113 GLN 113 113  113 GLN GLN B . n 
B 1 114 LEU 114 114  114 LEU LEU B . n 
B 1 115 LEU 115 115  115 LEU LEU B . n 
B 1 116 VAL 116 116  116 VAL VAL B . n 
B 1 117 ASP 117 117  117 ASP ASP B . n 
B 1 118 TYR 118 118  118 TYR TYR B . n 
B 1 119 ILE 119 119  119 ILE ILE B . n 
B 1 120 TYR 120 120  120 TYR TYR B . n 
B 1 121 HIS 121 121  121 HIS HIS B . n 
B 1 122 GLY 122 122  122 GLY GLY B . n 
B 1 123 THR 123 123  123 THR THR B . n 
B 1 124 VAL 124 124  124 VAL VAL B . n 
B 1 125 LYS 125 125  125 LYS LYS B . n 
B 1 126 LEU 126 126  126 LEU LEU B . n 
B 1 127 ARG 127 127  127 ARG ARG B . n 
B 1 128 ALA 128 128  128 ALA ALA B . n 
B 1 129 GLU 129 129  129 GLU GLU B . n 
B 1 130 GLU 130 130  130 GLU GLU B . n 
B 1 131 LEU 131 131  131 LEU LEU B . n 
B 1 132 GLN 132 132  132 GLN GLN B . n 
B 1 133 GLU 133 133  133 GLU GLU B . n 
B 1 134 ILE 134 134  134 ILE ILE B . n 
B 1 135 TYR 135 135  135 TYR TYR B . n 
B 1 136 GLU 136 136  136 GLU GLU B . n 
B 1 137 VAL 137 137  137 VAL VAL B . n 
B 1 138 SER 138 138  138 SER SER B . n 
B 1 139 ASP 139 139  139 ASP ASP B . n 
B 1 140 MET 140 140  140 MET MET B . n 
B 1 141 TYR 141 141  141 TYR TYR B . n 
B 1 142 GLN 142 142  142 GLN GLN B . n 
B 1 143 LEU 143 143  143 LEU LEU B . n 
B 1 144 THR 144 144  144 THR THR B . n 
B 1 145 SER 145 145  145 SER SER B . n 
B 1 146 LEU 146 146  146 LEU LEU B . n 
B 1 147 PHE 147 147  147 PHE PHE B . n 
B 1 148 GLU 148 148  148 GLU GLU B . n 
B 1 149 GLU 149 149  149 GLU GLU B . n 
B 1 150 CYS 150 150  150 CYS CYS B . n 
B 1 151 SER 151 151  151 SER SER B . n 
B 1 152 ARG 152 152  152 ARG ARG B . n 
B 1 153 PHE 153 153  153 PHE PHE B . n 
B 1 154 LEU 154 154  154 LEU LEU B . n 
B 1 155 ALA 155 155  155 ALA ALA B . n 
B 1 156 ARG 156 156  156 ARG ARG B . n 
B 1 157 THR 157 157  157 THR THR B . n 
B 1 158 VAL 158 158  158 VAL VAL B . n 
B 1 159 GLN 159 159  159 GLN GLN B . n 
B 1 160 VAL 160 160  160 VAL VAL B . n 
B 1 161 GLY 161 161  161 GLY GLY B . n 
B 1 162 ASN 162 162  162 ASN ASN B . n 
B 1 163 CYS 163 163  163 CYS CYS B . n 
B 1 164 LEU 164 164  164 LEU LEU B . n 
B 1 165 GLN 165 165  165 GLN GLN B . n 
B 1 166 VAL 166 166  166 VAL VAL B . n 
B 1 167 MET 167 167  167 MET MET B . n 
B 1 168 TRP 168 168  168 TRP TRP B . n 
B 1 169 LEU 169 169  169 LEU LEU B . n 
B 1 170 ALA 170 170  170 ALA ALA B . n 
B 1 171 ASP 171 171  171 ASP ASP B . n 
B 1 172 ARG 172 172  172 ARG ARG B . n 
B 1 173 HIS 173 173  173 HIS HIS B . n 
B 1 174 SER 174 174  174 SER SER B . n 
B 1 175 ASP 175 175  175 ASP ASP B . n 
B 1 176 PRO 176 176  176 PRO PRO B . n 
B 1 177 GLU 177 177  177 GLU GLU B . n 
B 1 178 LEU 178 178  178 LEU LEU B . n 
B 1 179 TYR 179 179  179 TYR TYR B . n 
B 1 180 THR 180 180  180 THR THR B . n 
B 1 181 ALA 181 181  181 ALA ALA B . n 
B 1 182 ALA 182 182  182 ALA ALA B . n 
B 1 183 LYS 183 183  183 LYS LYS B . n 
B 1 184 HIS 184 184  184 HIS HIS B . n 
B 1 185 CYS 185 185  185 CYS CYS B . n 
B 1 186 ALA 186 186  186 ALA ALA B . n 
B 1 187 LYS 187 187  187 LYS LYS B . n 
B 1 188 THR 188 188  188 THR THR B . n 
B 1 189 HIS 189 189  189 HIS HIS B . n 
B 1 190 LEU 190 190  190 LEU LEU B . n 
B 1 191 ALA 191 191  191 ALA ALA B . n 
B 1 192 GLN 192 192  192 GLN GLN B . n 
B 1 193 LEU 193 193  193 LEU LEU B . n 
B 1 194 GLN 194 194  194 GLN GLN B . n 
B 1 195 ASN 195 195  195 ASN ASN B . n 
B 1 196 THR 196 196  196 THR THR B . n 
B 1 197 GLU 197 197  197 GLU GLU B . n 
B 1 198 GLU 198 198  198 GLU GLU B . n 
B 1 199 PHE 199 199  199 PHE PHE B . n 
B 1 200 LEU 200 200  200 LEU LEU B . n 
B 1 201 HIS 201 201  201 HIS HIS B . n 
B 1 202 LEU 202 202  202 LEU LEU B . n 
B 1 203 PRO 203 203  203 PRO PRO B . n 
B 1 204 HIS 204 204  204 HIS HIS B . n 
B 1 205 ARG 205 205  205 ARG ARG B . n 
B 1 206 LEU 206 206  206 LEU LEU B . n 
B 1 207 LEU 207 207  207 LEU LEU B . n 
B 1 208 THR 208 208  208 THR THR B . n 
B 1 209 ASP 209 209  209 ASP ASP B . n 
B 1 210 ILE 210 210  210 ILE ILE B . n 
B 1 211 ILE 211 211  211 ILE ILE B . n 
B 1 212 SER 212 212  212 SER SER B . n 
B 1 213 ASP 213 213  213 ASP ASP B . n 
B 1 214 GLY 214 214  214 GLY GLY B . n 
B 1 215 VAL 215 215  215 VAL VAL B . n 
B 1 216 PRO 216 216  216 PRO PRO B . n 
B 1 217 CYS 217 217  217 CYS CYS B . n 
B 1 218 SER 218 218  218 SER SER B . n 
B 1 219 GLN 219 219  219 GLN GLN B . n 
B 1 220 ASN 220 220  220 ASN ASN B . n 
B 1 221 PRO 221 221  221 PRO PRO B . n 
B 1 222 THR 222 222  222 THR THR B . n 
B 1 223 GLU 223 223  223 GLU GLU B . n 
B 1 224 ALA 224 224  224 ALA ALA B . n 
B 1 225 ILE 225 225  225 ILE ILE B . n 
B 1 226 GLU 226 226  226 GLU GLU B . n 
B 1 227 ALA 227 227  227 ALA ALA B . n 
B 1 228 TRP 228 228  228 TRP TRP B . n 
B 1 229 ILE 229 229  229 ILE ILE B . n 
B 1 230 ASN 230 230  230 ASN ASN B . n 
B 1 231 PHE 231 231  231 PHE PHE B . n 
B 1 232 ASN 232 232  232 ASN ASN B . n 
B 1 233 LYS 233 233  233 LYS LYS B . n 
B 1 234 GLU 234 234  234 GLU GLU B . n 
B 1 235 GLU 235 235  235 GLU GLU B . n 
B 1 236 ARG 236 236  236 ARG ARG B . n 
B 1 237 GLU 237 237  237 GLU GLU B . n 
B 1 238 ALA 238 238  238 ALA ALA B . n 
B 1 239 PHE 239 239  239 PHE PHE B . n 
B 1 240 ALA 240 240  240 ALA ALA B . n 
B 1 241 GLU 241 241  241 GLU GLU B . n 
B 1 242 SER 242 242  242 SER SER B . n 
B 1 243 LEU 243 243  243 LEU LEU B . n 
B 1 244 ARG 244 244  244 ARG ARG B . n 
B 1 245 THR 245 245  245 THR THR B . n 
B 1 246 SER 246 246  246 SER SER B . n 
B 1 247 LEU 247 247  247 LEU LEU B . n 
B 1 248 LYS 248 248  248 LYS LYS B . n 
B 1 249 GLU 249 249  249 GLU GLU B . n 
B 1 250 ILE 250 250  250 ILE ILE B . n 
B 1 251 GLY 251 251  251 GLY GLY B . n 
B 1 252 GLU 252 252  252 GLU GLU B . n 
B 1 253 ASN 253 253  253 ASN ASN B . n 
B 1 254 VAL 254 254  254 VAL VAL B . n 
B 1 255 HIS 255 255  255 HIS HIS B . n 
B 1 256 ILE 256 256  256 ILE ILE B . n 
B 1 257 TYR 257 257  257 TYR TYR B . n 
B 1 258 LEU 258 258  258 LEU LEU B . n 
B 1 259 ILE 259 259  259 ILE ILE B . n 
B 1 260 GLY 260 260  260 GLY GLY B . n 
B 1 261 LYS 261 261  261 LYS LYS B . n 
B 1 262 GLU 262 262  262 GLU GLU B . n 
B 1 263 SER 263 263  263 SER SER B . n 
B 1 264 SER 264 264  264 SER SER B . n 
B 1 265 ARG 265 265  265 ARG ARG B . n 
B 1 266 THR 266 266  266 THR THR B . n 
B 1 267 HIS 267 267  267 HIS HIS B . n 
B 1 268 SER 268 268  268 SER SER B . n 
B 1 269 LEU 269 269  269 LEU LEU B . n 
B 1 270 ALA 270 270  270 ALA ALA B . n 
B 1 271 VAL 271 271  271 VAL VAL B . n 
B 1 272 SER 272 272  272 SER SER B . n 
B 1 273 LEU 273 273  273 LEU LEU B . n 
B 1 274 HIS 274 274  274 HIS HIS B . n 
B 1 275 CYS 275 275  275 CYS CYS B . n 
B 1 276 ALA 276 276  276 ALA ALA B . n 
B 1 277 GLU 277 277  277 GLU GLU B . n 
B 1 278 ASP 278 278  278 ASP ASP B . n 
B 1 279 ASP 279 279  279 ASP ASP B . n 
B 1 280 SER 280 280  280 SER SER B . n 
B 1 281 ILE 281 281  281 ILE ILE B . n 
B 1 282 SER 282 282  282 SER SER B . n 
B 1 283 VAL 283 283  283 VAL VAL B . n 
B 1 284 SER 284 284  284 SER SER B . n 
B 1 285 GLY 285 285  285 GLY GLY B . n 
B 1 286 GLN 286 286  286 GLN GLN B . n 
B 1 287 ASN 287 287  287 ASN ASN B . n 
B 1 288 SER 288 288  288 SER SER B . n 
B 1 289 LEU 289 289  289 LEU LEU B . n 
B 1 290 CYS 290 290  290 CYS CYS B . n 
B 1 291 HIS 291 291  291 HIS HIS B . n 
B 1 292 GLN 292 292  292 GLN GLN B . n 
B 1 293 ILE 293 293  293 ILE ILE B . n 
B 1 294 THR 294 294  294 THR THR B . n 
B 1 295 ALA 295 295  295 ALA ALA B . n 
B 1 296 ALA 296 296  296 ALA ALA B . n 
B 1 297 CYS 297 297  297 CYS CYS B . n 
B 1 298 LYS 298 298  298 LYS LYS B . n 
B 1 299 HIS 299 299  299 HIS HIS B . n 
B 1 300 GLY 300 300  300 GLY GLY B . n 
B 1 301 GLY 301 301  301 GLY GLY B . n 
B 1 302 ASP 302 302  302 ASP ASP B . n 
B 1 303 LEU 303 303  303 LEU LEU B . n 
B 1 304 TYR 304 304  304 TYR TYR B . n 
B 1 305 VAL 305 305  305 VAL VAL B . n 
B 1 306 VAL 306 306  306 VAL VAL B . n 
B 1 307 GLY 307 307  307 GLY GLY B . n 
B 1 308 GLY 308 308  308 GLY GLY B . n 
B 1 309 SER 309 309  309 SER SER B . n 
B 1 310 THR 310 310  310 THR THR B . n 
B 1 311 THR 311 311  311 THR THR B . n 
B 1 312 TYR 312 312  312 TYR TYR B . n 
B 1 313 MET 313 313  313 MET MET B . n 
B 1 314 LEU 314 314  314 LEU LEU B . n 
B 1 315 ARG 315 315  315 ARG ARG B . n 
B 1 316 MET 316 316  316 MET MET B . n 
B 1 317 TRP 317 317  317 TRP TRP B . n 
B 1 318 LYS 318 318  318 LYS LYS B . n 
B 1 319 CYS 319 319  319 CYS CYS B . n 
B 1 320 ASN 320 320  320 ASN ASN B . n 
B 1 321 ASN 321 321  321 ASN ASN B . n 
B 1 322 ALA 322 322  322 ALA ALA B . n 
B 1 323 THR 323 323  323 THR THR B . n 
B 1 324 VAL 324 324  324 VAL VAL B . n 
B 1 325 ASP 325 325  325 ASP ASP B . n 
B 1 326 TRP 326 326  326 TRP TRP B . n 
B 1 327 GLU 327 327  327 GLU GLU B . n 
B 1 328 TRP 328 328  328 TRP TRP B . n 
B 1 329 CYS 329 329  329 CYS CYS B . n 
B 1 330 ALA 330 330  330 ALA ALA B . n 
B 1 331 PRO 331 331  331 PRO PRO B . n 
B 1 332 LEU 332 332  332 LEU LEU B . n 
B 1 333 PRO 333 333  333 PRO PRO B . n 
B 1 334 ARG 334 334  334 ARG ARG B . n 
B 1 335 ASP 335 335  335 ASP ASP B . n 
B 1 336 ARG 336 336  336 ARG ARG B . n 
B 1 337 LEU 337 337  337 LEU LEU B . n 
B 1 338 GLN 338 338  338 GLN GLN B . n 
B 1 339 HIS 339 339  339 HIS HIS B . n 
B 1 340 THR 340 340  340 THR THR B . n 
B 1 341 LEU 341 341  341 LEU LEU B . n 
B 1 342 VAL 342 342  342 VAL VAL B . n 
B 1 343 SER 343 343  343 SER SER B . n 
B 1 344 VAL 344 344  344 VAL VAL B . n 
B 1 345 PRO 345 345  345 PRO PRO B . n 
B 1 346 GLY 346 346  346 GLY GLY B . n 
B 1 347 LYS 347 347  347 LYS LYS B . n 
B 1 348 ASP 348 348  348 ASP ASP B . n 
B 1 349 ALA 349 349  349 ALA ALA B . n 
B 1 350 ILE 350 350  350 ILE ILE B . n 
B 1 351 TYR 351 351  351 TYR TYR B . n 
B 1 352 SER 352 352  352 SER SER B . n 
B 1 353 LEU 353 353  353 LEU LEU B . n 
B 1 354 GLY 354 354  354 GLY GLY B . n 
B 1 355 GLY 355 355  355 GLY GLY B . n 
B 1 356 LYS 356 356  356 LYS LYS B . n 
B 1 357 THR 357 357  357 THR THR B . n 
B 1 358 LEU 358 358  358 LEU LEU B . n 
B 1 359 GLN 359 359  359 GLN GLN B . n 
B 1 360 ASP 360 360  360 ASP ASP B . n 
B 1 361 THR 361 361  361 THR THR B . n 
B 1 362 LEU 362 362  362 LEU LEU B . n 
B 1 363 SER 363 363  363 SER SER B . n 
B 1 364 ASN 364 364  364 ASN ASN B . n 
B 1 365 ALA 365 365  365 ALA ALA B . n 
B 1 366 VAL 366 366  366 VAL VAL B . n 
B 1 367 ILE 367 367  367 ILE ILE B . n 
B 1 368 TYR 368 368  368 TYR TYR B . n 
B 1 369 TYR 369 369  369 TYR TYR B . n 
B 1 370 ARG 370 370  370 ARG ARG B . n 
B 1 371 VAL 371 371  371 VAL VAL B . n 
B 1 372 GLY 372 372  372 GLY GLY B . n 
B 1 373 ASP 373 373  373 ASP ASP B . n 
B 1 374 ASN 374 374  374 ASN ASN B . n 
B 1 375 VAL 375 375  375 VAL VAL B . n 
B 1 376 TRP 376 376  376 TRP TRP B . n 
B 1 377 THR 377 377  377 THR THR B . n 
B 1 378 GLU 378 378  378 GLU GLU B . n 
B 1 379 THR 379 379  379 THR THR B . n 
B 1 380 THR 380 380  380 THR THR B . n 
B 1 381 GLN 381 381  381 GLN GLN B . n 
B 1 382 LEU 382 382  382 LEU LEU B . n 
B 1 383 GLU 383 383  383 GLU GLU B . n 
B 1 384 VAL 384 384  384 VAL VAL B . n 
B 1 385 ALA 385 385  385 ALA ALA B . n 
B 1 386 VAL 386 386  386 VAL VAL B . n 
B 1 387 SER 387 387  387 SER SER B . n 
B 1 388 GLY 388 388  388 GLY GLY B . n 
B 1 389 ALA 389 389  389 ALA ALA B . n 
B 1 390 ALA 390 390  390 ALA ALA B . n 
B 1 391 GLY 391 391  391 GLY GLY B . n 
B 1 392 ALA 392 392  392 ALA ALA B . n 
B 1 393 ASN 393 393  393 ASN ASN B . n 
B 1 394 LEU 394 394  394 LEU LEU B . n 
B 1 395 ASN 395 395  395 ASN ASN B . n 
B 1 396 GLY 396 396  396 GLY GLY B . n 
B 1 397 ILE 397 397  397 ILE ILE B . n 
B 1 398 ILE 398 398  398 ILE ILE B . n 
B 1 399 TYR 399 399  399 TYR TYR B . n 
B 1 400 LEU 400 400  400 LEU LEU B . n 
B 1 401 LEU 401 401  401 LEU LEU B . n 
B 1 402 GLY 402 402  402 GLY GLY B . n 
B 1 403 GLY 403 403  403 GLY GLY B . n 
B 1 404 GLU 404 404  404 GLU GLU B . n 
B 1 405 GLU 405 405  405 GLU GLU B . n 
B 1 406 ASN 406 406  406 ASN ASN B . n 
B 1 407 ASP 407 407  407 ASP ASP B . n 
B 1 408 LEU 408 408  408 LEU LEU B . n 
B 1 409 ASP 409 409  409 ASP ASP B . n 
B 1 410 PHE 410 410  410 PHE PHE B . n 
B 1 411 PHE 411 411  411 PHE PHE B . n 
B 1 412 THR 412 412  412 THR THR B . n 
B 1 413 LYS 413 413  413 LYS LYS B . n 
B 1 414 PRO 414 414  414 PRO PRO B . n 
B 1 415 SER 415 415  415 SER SER B . n 
B 1 416 ARG 416 416  416 ARG ARG B . n 
B 1 417 LEU 417 417  417 LEU LEU B . n 
B 1 418 ILE 418 418  418 ILE ILE B . n 
B 1 419 GLN 419 419  419 GLN GLN B . n 
B 1 420 CYS 420 420  420 CYS CYS B . n 
B 1 421 PHE 421 421  421 PHE PHE B . n 
B 1 422 ASP 422 422  422 ASP ASP B . n 
B 1 423 THR 423 423  423 THR THR B . n 
B 1 424 GLU 424 424  424 GLU GLU B . n 
B 1 425 THR 425 425  425 THR THR B . n 
B 1 426 ASP 426 426  426 ASP ASP B . n 
B 1 427 LYS 427 427  427 LYS LYS B . n 
B 1 428 CYS 428 428  428 CYS CYS B . n 
B 1 429 HIS 429 429  429 HIS HIS B . n 
B 1 430 VAL 430 430  430 VAL VAL B . n 
B 1 431 LYS 431 431  431 LYS LYS B . n 
B 1 432 PRO 432 432  432 PRO PRO B . n 
B 1 433 TYR 433 433  433 TYR TYR B . n 
B 1 434 VAL 434 434  434 VAL VAL B . n 
B 1 435 LEU 435 435  435 LEU LEU B . n 
B 1 436 PRO 436 436  436 PRO PRO B . n 
B 1 437 PHE 437 437  437 PHE PHE B . n 
B 1 438 ALA 438 438  438 ALA ALA B . n 
B 1 439 GLY 439 439  439 GLY GLY B . n 
B 1 440 ARG 440 440  440 ARG ARG B . n 
B 1 441 MET 441 441  441 MET MET B . n 
B 1 442 HIS 442 442  442 HIS HIS B . n 
B 1 443 ALA 443 443  443 ALA ALA B . n 
B 1 444 ALA 444 444  444 ALA ALA B . n 
B 1 445 VAL 445 445  445 VAL VAL B . n 
B 1 446 HIS 446 446  446 HIS HIS B . n 
B 1 447 LYS 447 447  447 LYS LYS B . n 
B 1 448 ASP 448 448  448 ASP ASP B . n 
B 1 449 LEU 449 449  449 LEU LEU B . n 
B 1 450 VAL 450 450  450 VAL VAL B . n 
B 1 451 PHE 451 451  451 PHE PHE B . n 
B 1 452 ILE 452 452  452 ILE ILE B . n 
B 1 453 VAL 453 453  453 VAL VAL B . n 
B 1 454 ALA 454 454  454 ALA ALA B . n 
B 1 455 GLU 455 455  455 GLU GLU B . n 
B 1 456 GLY 456 456  456 GLY GLY B . n 
B 1 457 ASP 457 457  457 ASP ASP B . n 
B 1 458 SER 458 458  458 SER SER B . n 
B 1 459 LEU 459 459  459 LEU LEU B . n 
B 1 460 VAL 460 460  460 VAL VAL B . n 
B 1 461 CYS 461 461  461 CYS CYS B . n 
B 1 462 TYR 462 462  462 TYR TYR B . n 
B 1 463 ASN 463 463  463 ASN ASN B . n 
B 1 464 PRO 464 464  464 PRO PRO B . n 
B 1 465 LEU 465 465  465 LEU LEU B . n 
B 1 466 LEU 466 466  466 LEU LEU B . n 
B 1 467 ASP 467 467  467 ASP ASP B . n 
B 1 468 SER 468 468  468 SER SER B . n 
B 1 469 PHE 469 469  469 PHE PHE B . n 
B 1 470 THR 470 470  470 THR THR B . n 
B 1 471 ARG 471 471  471 ARG ARG B . n 
B 1 472 LEU 472 472  472 LEU LEU B . n 
B 1 473 CYS 473 473  473 CYS CYS B . n 
B 1 474 LEU 474 474  474 LEU LEU B . n 
B 1 475 PRO 475 475  475 PRO PRO B . n 
B 1 476 GLU 476 476  476 GLU GLU B . n 
B 1 477 ALA 477 477  477 ALA ALA B . n 
B 1 478 TRP 478 478  ?   ?   ?   B . n 
B 1 479 SER 479 479  ?   ?   ?   B . n 
B 1 480 SER 480 480  ?   ?   ?   B . n 
B 1 481 ALA 481 481  ?   ?   ?   B . n 
B 1 482 PRO 482 482  ?   ?   ?   B . n 
B 1 483 SER 483 483  483 SER SER B . n 
B 1 484 LEU 484 484  484 LEU LEU B . n 
B 1 485 TRP 485 485  485 TRP TRP B . n 
B 1 486 LYS 486 486  486 LYS LYS B . n 
B 1 487 ILE 487 487  487 ILE ILE B . n 
B 1 488 ALA 488 488  488 ALA ALA B . n 
B 1 489 SER 489 489  489 SER SER B . n 
B 1 490 CYS 490 490  490 CYS CYS B . n 
B 1 491 ASN 491 491  491 ASN ASN B . n 
B 1 492 GLY 492 492  492 GLY GLY B . n 
B 1 493 SER 493 493  493 SER SER B . n 
B 1 494 ILE 494 494  494 ILE ILE B . n 
B 1 495 TYR 495 495  495 TYR TYR B . n 
B 1 496 VAL 496 496  496 VAL VAL B . n 
B 1 497 PHE 497 497  497 PHE PHE B . n 
B 1 498 ARG 498 498  498 ARG ARG B . n 
B 1 499 ASP 499 499  499 ASP ASP B . n 
B 1 500 ARG 500 500  500 ARG ARG B . n 
B 1 501 TYR 501 501  501 TYR TYR B . n 
B 1 502 LYS 502 502  502 LYS LYS B . n 
B 1 503 LYS 503 503  503 LYS LYS B . n 
B 1 504 GLY 504 504  504 GLY GLY B . n 
B 1 505 ASP 505 505  505 ASP ASP B . n 
B 1 506 ALA 506 506  506 ALA ALA B . n 
B 1 507 ASN 507 507  507 ASN ASN B . n 
B 1 508 THR 508 508  508 THR THR B . n 
B 1 509 TYR 509 509  509 TYR TYR B . n 
B 1 510 LYS 510 510  510 LYS LYS B . n 
B 1 511 LEU 511 511  511 LEU LEU B . n 
B 1 512 ASP 512 512  512 ASP ASP B . n 
B 1 513 PRO 513 513  513 PRO PRO B . n 
B 1 514 ALA 514 514  514 ALA ALA B . n 
B 1 515 THR 515 515  515 THR THR B . n 
B 1 516 SER 516 516  516 SER SER B . n 
B 1 517 ALA 517 517  517 ALA ALA B . n 
B 1 518 VAL 518 518  518 VAL VAL B . n 
B 1 519 THR 519 519  519 THR THR B . n 
B 1 520 VAL 520 520  520 VAL VAL B . n 
B 1 521 THR 521 521  521 THR THR B . n 
B 1 522 ARG 522 522  522 ARG ARG B . n 
B 1 523 GLY 523 523  523 GLY GLY B . n 
B 1 524 ILE 524 524  524 ILE ILE B . n 
B 1 525 LYS 525 525  525 LYS LYS B . n 
B 1 526 VAL 526 526  526 VAL VAL B . n 
B 1 527 LEU 527 527  527 LEU LEU B . n 
B 1 528 LEU 528 528  528 LEU LEU B . n 
B 1 529 THR 529 529  529 THR THR B . n 
B 1 530 ASN 530 530  530 ASN ASN B . n 
B 1 531 LEU 531 531  531 LEU LEU B . n 
B 1 532 GLN 532 532  532 GLN GLN B . n 
B 1 533 PHE 533 533  533 PHE PHE B . n 
B 1 534 VAL 534 534  534 VAL VAL B . n 
B 1 535 LEU 535 535  535 LEU LEU B . n 
B 1 536 ALA 536 536  536 ALA ALA B . n 
C 2 1   MET 1   1    ?   ?   ?   C . n 
C 2 2   ALA 2   2    ?   ?   ?   C . n 
C 2 3   GLN 3   3    ?   ?   ?   C . n 
C 2 4   THR 4   4    ?   ?   ?   C . n 
C 2 5   GLN 5   5    ?   ?   ?   C . n 
C 2 6   GLY 6   6    ?   ?   ?   C . n 
C 2 7   THR 7   7    ?   ?   ?   C . n 
C 2 8   ARG 8   8    8   ARG ARG C . n 
C 2 9   ARG 9   9    9   ARG ARG C . n 
C 2 10  LYS 10  10   10  LYS LYS C . n 
C 2 11  VAL 11  11   11  VAL VAL C . n 
C 2 12  CYS 12  12   12  CYS CYS C . n 
C 2 13  TYR 13  13   13  TYR TYR C . n 
C 2 14  TYR 14  14   14  TYR TYR C . n 
C 2 15  TYR 15  15   15  TYR TYR C . n 
C 2 16  ASP 16  16   16  ASP ASP C . n 
C 2 17  GLY 17  17   17  GLY GLY C . n 
C 2 18  ASP 18  18   18  ASP ASP C . n 
C 2 19  VAL 19  19   19  VAL VAL C . n 
C 2 20  GLY 20  20   20  GLY GLY C . n 
C 2 21  ASN 21  21   21  ASN ASN C . n 
C 2 22  TYR 22  22   22  TYR TYR C . n 
C 2 23  TYR 23  23   23  TYR TYR C . n 
C 2 24  TYR 24  24   24  TYR TYR C . n 
C 2 25  GLY 25  25   25  GLY GLY C . n 
C 2 26  GLN 26  26   26  GLN GLN C . n 
C 2 27  GLY 27  27   27  GLY GLY C . n 
C 2 28  HIS 28  28   28  HIS HIS C . n 
C 2 29  PRO 29  29   29  PRO PRO C . n 
C 2 30  MET 30  30   30  MET MET C . n 
C 2 31  LYS 31  31   31  LYS LYS C . n 
C 2 32  PRO 32  32   32  PRO PRO C . n 
C 2 33  HIS 33  33   33  HIS HIS C . n 
C 2 34  ARG 34  34   34  ARG ARG C . n 
C 2 35  ILE 35  35   35  ILE ILE C . n 
C 2 36  ARG 36  36   36  ARG ARG C . n 
C 2 37  MET 37  37   37  MET MET C . n 
C 2 38  THR 38  38   38  THR THR C . n 
C 2 39  HIS 39  39   39  HIS HIS C . n 
C 2 40  ASN 40  40   40  ASN ASN C . n 
C 2 41  LEU 41  41   41  LEU LEU C . n 
C 2 42  LEU 42  42   42  LEU LEU C . n 
C 2 43  LEU 43  43   43  LEU LEU C . n 
C 2 44  ASN 44  44   44  ASN ASN C . n 
C 2 45  TYR 45  45   45  TYR TYR C . n 
C 2 46  GLY 46  46   46  GLY GLY C . n 
C 2 47  LEU 47  47   47  LEU LEU C . n 
C 2 48  TYR 48  48   48  TYR TYR C . n 
C 2 49  ARG 49  49   49  ARG ARG C . n 
C 2 50  LYS 50  50   50  LYS LYS C . n 
C 2 51  MET 51  51   51  MET MET C . n 
C 2 52  GLU 52  52   52  GLU GLU C . n 
C 2 53  ILE 53  53   53  ILE ILE C . n 
C 2 54  TYR 54  54   54  TYR TYR C . n 
C 2 55  ARG 55  55   55  ARG ARG C . n 
C 2 56  PRO 56  56   56  PRO PRO C . n 
C 2 57  HIS 57  57   57  HIS HIS C . n 
C 2 58  LYS 58  58   58  LYS LYS C . n 
C 2 59  ALA 59  59   59  ALA ALA C . n 
C 2 60  ASN 60  60   60  ASN ASN C . n 
C 2 61  ALA 61  61   61  ALA ALA C . n 
C 2 62  GLU 62  62   62  GLU GLU C . n 
C 2 63  GLU 63  63   63  GLU GLU C . n 
C 2 64  MET 64  64   64  MET MET C . n 
C 2 65  THR 65  65   65  THR THR C . n 
C 2 66  LYS 66  66   66  LYS LYS C . n 
C 2 67  TYR 67  67   67  TYR TYR C . n 
C 2 68  HIS 68  68   68  HIS HIS C . n 
C 2 69  SER 69  69   69  SER SER C . n 
C 2 70  ASP 70  70   70  ASP ASP C . n 
C 2 71  ASP 71  71   71  ASP ASP C . n 
C 2 72  TYR 72  72   72  TYR TYR C . n 
C 2 73  ILE 73  73   73  ILE ILE C . n 
C 2 74  LYS 74  74   74  LYS LYS C . n 
C 2 75  PHE 75  75   75  PHE PHE C . n 
C 2 76  LEU 76  76   76  LEU LEU C . n 
C 2 77  ARG 77  77   77  ARG ARG C . n 
C 2 78  SER 78  78   78  SER SER C . n 
C 2 79  ILE 79  79   79  ILE ILE C . n 
C 2 80  ARG 80  80   80  ARG ARG C . n 
C 2 81  PRO 81  81   81  PRO PRO C . n 
C 2 82  ASP 82  82   82  ASP ASP C . n 
C 2 83  ASN 83  83   83  ASN ASN C . n 
C 2 84  MET 84  84   84  MET MET C . n 
C 2 85  SER 85  85   85  SER SER C . n 
C 2 86  GLU 86  86   86  GLU GLU C . n 
C 2 87  TYR 87  87   87  TYR TYR C . n 
C 2 88  SER 88  88   88  SER SER C . n 
C 2 89  LYS 89  89   89  LYS LYS C . n 
C 2 90  GLN 90  90   90  GLN GLN C . n 
C 2 91  MET 91  91   91  MET MET C . n 
C 2 92  GLN 92  92   92  GLN GLN C . n 
C 2 93  ARG 93  93   93  ARG ARG C . n 
C 2 94  PHE 94  94   94  PHE PHE C . n 
C 2 95  ASN 95  95   95  ASN ASN C . n 
C 2 96  VAL 96  96   96  VAL VAL C . n 
C 2 97  GLY 97  97   97  GLY GLY C . n 
C 2 98  GLU 98  98   98  GLU GLU C . n 
C 2 99  ASP 99  99   99  ASP ASP C . n 
C 2 100 CYS 100 100  100 CYS CYS C . n 
C 2 101 PRO 101 101  101 PRO PRO C . n 
C 2 102 VAL 102 102  102 VAL VAL C . n 
C 2 103 PHE 103 103  103 PHE PHE C . n 
C 2 104 ASP 104 104  104 ASP ASP C . n 
C 2 105 GLY 105 105  105 GLY GLY C . n 
C 2 106 LEU 106 106  106 LEU LEU C . n 
C 2 107 PHE 107 107  107 PHE PHE C . n 
C 2 108 GLU 108 108  108 GLU GLU C . n 
C 2 109 PHE 109 109  109 PHE PHE C . n 
C 2 110 CYS 110 110  110 CYS CYS C . n 
C 2 111 GLN 111 111  111 GLN GLN C . n 
C 2 112 LEU 112 112  112 LEU LEU C . n 
C 2 113 SER 113 113  113 SER SER C . n 
C 2 114 THR 114 114  114 THR THR C . n 
C 2 115 GLY 115 115  115 GLY GLY C . n 
C 2 116 GLY 116 116  116 GLY GLY C . n 
C 2 117 SER 117 117  117 SER SER C . n 
C 2 118 VAL 118 118  118 VAL VAL C . n 
C 2 119 ALA 119 119  119 ALA ALA C . n 
C 2 120 SER 120 120  120 SER SER C . n 
C 2 121 ALA 121 121  121 ALA ALA C . n 
C 2 122 VAL 122 122  122 VAL VAL C . n 
C 2 123 LYS 123 123  123 LYS LYS C . n 
C 2 124 LEU 124 124  124 LEU LEU C . n 
C 2 125 ASN 125 125  125 ASN ASN C . n 
C 2 126 LYS 126 126  126 LYS LYS C . n 
C 2 127 GLN 127 127  127 GLN GLN C . n 
C 2 128 GLN 128 128  128 GLN GLN C . n 
C 2 129 THR 129 129  129 THR THR C . n 
C 2 130 ASP 130 130  130 ASP ASP C . n 
C 2 131 ILE 131 131  131 ILE ILE C . n 
C 2 132 ALA 132 132  132 ALA ALA C . n 
C 2 133 VAL 133 133  133 VAL VAL C . n 
C 2 134 ASN 134 134  134 ASN ASN C . n 
C 2 135 TRP 135 135  135 TRP TRP C . n 
C 2 136 ALA 136 136  136 ALA ALA C . n 
C 2 137 GLY 137 137  137 GLY GLY C . n 
C 2 138 GLY 138 138  138 GLY GLY C . n 
C 2 139 LEU 139 139  139 LEU LEU C . n 
C 2 140 HIS 140 140  140 HIS HIS C . n 
C 2 141 HIS 141 141  141 HIS HIS C . n 
C 2 142 ALA 142 142  142 ALA ALA C . n 
C 2 143 LYS 143 143  143 LYS LYS C . n 
C 2 144 LYS 144 144  144 LYS LYS C . n 
C 2 145 SER 145 145  145 SER SER C . n 
C 2 146 GLU 146 146  146 GLU GLU C . n 
C 2 147 ALA 147 147  147 ALA ALA C . n 
C 2 148 SER 148 148  148 SER SER C . n 
C 2 149 GLY 149 149  149 GLY GLY C . n 
C 2 150 PHE 150 150  150 PHE PHE C . n 
C 2 151 CYS 151 151  151 CYS CYS C . n 
C 2 152 TYR 152 152  152 TYR TYR C . n 
C 2 153 VAL 153 153  153 VAL VAL C . n 
C 2 154 ASN 154 154  154 ASN ASN C . n 
C 2 155 ASP 155 155  155 ASP ASP C . n 
C 2 156 ILE 156 156  156 ILE ILE C . n 
C 2 157 VAL 157 157  157 VAL VAL C . n 
C 2 158 LEU 158 158  158 LEU LEU C . n 
C 2 159 ALA 159 159  159 ALA ALA C . n 
C 2 160 ILE 160 160  160 ILE ILE C . n 
C 2 161 LEU 161 161  161 LEU LEU C . n 
C 2 162 GLU 162 162  162 GLU GLU C . n 
C 2 163 LEU 163 163  163 LEU LEU C . n 
C 2 164 LEU 164 164  164 LEU LEU C . n 
C 2 165 LYS 165 165  165 LYS LYS C . n 
C 2 166 TYR 166 166  166 TYR TYR C . n 
C 2 167 HIS 167 167  167 HIS HIS C . n 
C 2 168 GLN 168 168  168 GLN GLN C . n 
C 2 169 ARG 169 169  169 ARG ARG C . n 
C 2 170 VAL 170 170  170 VAL VAL C . n 
C 2 171 LEU 171 171  171 LEU LEU C . n 
C 2 172 TYR 172 172  172 TYR TYR C . n 
C 2 173 ILE 173 173  173 ILE ILE C . n 
C 2 174 ASP 174 174  174 ASP ASP C . n 
C 2 175 ILE 175 175  175 ILE ILE C . n 
C 2 176 ASP 176 176  176 ASP ASP C . n 
C 2 177 ILE 177 177  177 ILE ILE C . n 
C 2 178 HIS 178 178  178 HIS HIS C . n 
C 2 179 HIS 179 179  179 HIS HIS C . n 
C 2 180 GLY 180 180  180 GLY GLY C . n 
C 2 181 ASP 181 181  181 ASP ASP C . n 
C 2 182 GLY 182 182  182 GLY GLY C . n 
C 2 183 VAL 183 183  183 VAL VAL C . n 
C 2 184 GLU 184 184  184 GLU GLU C . n 
C 2 185 GLU 185 185  185 GLU GLU C . n 
C 2 186 ALA 186 186  186 ALA ALA C . n 
C 2 187 PHE 187 187  187 PHE PHE C . n 
C 2 188 TYR 188 188  188 TYR TYR C . n 
C 2 189 THR 189 189  189 THR THR C . n 
C 2 190 THR 190 190  190 THR THR C . n 
C 2 191 ASP 191 191  191 ASP ASP C . n 
C 2 192 ARG 192 192  192 ARG ARG C . n 
C 2 193 VAL 193 193  193 VAL VAL C . n 
C 2 194 MET 194 194  194 MET MET C . n 
C 2 195 THR 195 195  195 THR THR C . n 
C 2 196 VAL 196 196  196 VAL VAL C . n 
C 2 197 SER 197 197  197 SER SER C . n 
C 2 198 PHE 198 198  198 PHE PHE C . n 
C 2 199 HIS 199 199  199 HIS HIS C . n 
C 2 200 LYS 200 200  200 LYS LYS C . n 
C 2 201 TYR 201 201  201 TYR TYR C . n 
C 2 202 GLY 202 202  202 GLY GLY C . n 
C 2 203 GLU 203 203  203 GLU GLU C . n 
C 2 204 TYR 204 204  204 TYR TYR C . n 
C 2 205 PHE 205 205  205 PHE PHE C . n 
C 2 206 PRO 206 206  206 PRO PRO C . n 
C 2 207 GLY 207 207  207 GLY GLY C . n 
C 2 208 THR 208 208  208 THR THR C . n 
C 2 209 GLY 209 209  209 GLY GLY C . n 
C 2 210 ASP 210 210  210 ASP ASP C . n 
C 2 211 LEU 211 211  211 LEU LEU C . n 
C 2 212 ARG 212 212  212 ARG ARG C . n 
C 2 213 ASP 213 213  213 ASP ASP C . n 
C 2 214 ILE 214 214  214 ILE ILE C . n 
C 2 215 GLY 215 215  215 GLY GLY C . n 
C 2 216 ALA 216 216  216 ALA ALA C . n 
C 2 217 GLY 217 217  217 GLY GLY C . n 
C 2 218 LYS 218 218  218 LYS LYS C . n 
C 2 219 GLY 219 219  219 GLY GLY C . n 
C 2 220 LYS 220 220  220 LYS LYS C . n 
C 2 221 TYR 221 221  221 TYR TYR C . n 
C 2 222 TYR 222 222  222 TYR TYR C . n 
C 2 223 ALA 223 223  223 ALA ALA C . n 
C 2 224 VAL 224 224  224 VAL VAL C . n 
C 2 225 ASN 225 225  225 ASN ASN C . n 
C 2 226 TYR 226 226  226 TYR TYR C . n 
C 2 227 PRO 227 227  227 PRO PRO C . n 
C 2 228 LEU 228 228  228 LEU LEU C . n 
C 2 229 ARG 229 229  229 ARG ARG C . n 
C 2 230 ASP 230 230  230 ASP ASP C . n 
C 2 231 GLY 231 231  231 GLY GLY C . n 
C 2 232 ILE 232 232  232 ILE ILE C . n 
C 2 233 ASP 233 233  233 ASP ASP C . n 
C 2 234 ASP 234 234  234 ASP ASP C . n 
C 2 235 GLU 235 235  235 GLU GLU C . n 
C 2 236 SER 236 236  236 SER SER C . n 
C 2 237 TYR 237 237  237 TYR TYR C . n 
C 2 238 GLU 238 238  238 GLU GLU C . n 
C 2 239 ALA 239 239  239 ALA ALA C . n 
C 2 240 ILE 240 240  240 ILE ILE C . n 
C 2 241 PHE 241 241  241 PHE PHE C . n 
C 2 242 LYS 242 242  242 LYS LYS C . n 
C 2 243 PRO 243 243  243 PRO PRO C . n 
C 2 244 VAL 244 244  244 VAL VAL C . n 
C 2 245 MET 245 245  245 MET MET C . n 
C 2 246 SER 246 246  246 SER SER C . n 
C 2 247 LYS 247 247  247 LYS LYS C . n 
C 2 248 VAL 248 248  248 VAL VAL C . n 
C 2 249 MET 249 249  249 MET MET C . n 
C 2 250 GLU 250 250  250 GLU GLU C . n 
C 2 251 MET 251 251  251 MET MET C . n 
C 2 252 PHE 252 252  252 PHE PHE C . n 
C 2 253 GLN 253 253  253 GLN GLN C . n 
C 2 254 PRO 254 254  254 PRO PRO C . n 
C 2 255 SER 255 255  255 SER SER C . n 
C 2 256 ALA 256 256  256 ALA ALA C . n 
C 2 257 VAL 257 257  257 VAL VAL C . n 
C 2 258 VAL 258 258  258 VAL VAL C . n 
C 2 259 LEU 259 259  259 LEU LEU C . n 
C 2 260 GLN 260 260  260 GLN GLN C . n 
C 2 261 CYS 261 261  261 CYS CYS C . n 
C 2 262 GLY 262 262  262 GLY GLY C . n 
C 2 263 SER 263 263  263 SER SER C . n 
C 2 264 ASP 264 264  264 ASP ASP C . n 
C 2 265 SER 265 265  265 SER SER C . n 
C 2 266 LEU 266 266  266 LEU LEU C . n 
C 2 267 SER 267 267  267 SER SER C . n 
C 2 268 GLY 268 268  268 GLY GLY C . n 
C 2 269 ASP 269 269  269 ASP ASP C . n 
C 2 270 ARG 270 270  270 ARG ARG C . n 
C 2 271 LEU 271 271  271 LEU LEU C . n 
C 2 272 GLY 272 272  272 GLY GLY C . n 
C 2 273 CYS 273 273  273 CYS CYS C . n 
C 2 274 PHE 274 274  274 PHE PHE C . n 
C 2 275 ASN 275 275  275 ASN ASN C . n 
C 2 276 LEU 276 276  276 LEU LEU C . n 
C 2 277 THR 277 277  277 THR THR C . n 
C 2 278 ILE 278 278  278 ILE ILE C . n 
C 2 279 LYS 279 279  279 LYS LYS C . n 
C 2 280 GLY 280 280  280 GLY GLY C . n 
C 2 281 HIS 281 281  281 HIS HIS C . n 
C 2 282 ALA 282 282  282 ALA ALA C . n 
C 2 283 LYS 283 283  283 LYS LYS C . n 
C 2 284 CYS 284 284  284 CYS CYS C . n 
C 2 285 VAL 285 285  285 VAL VAL C . n 
C 2 286 GLU 286 286  286 GLU GLU C . n 
C 2 287 PHE 287 287  287 PHE PHE C . n 
C 2 288 VAL 288 288  288 VAL VAL C . n 
C 2 289 LYS 289 289  289 LYS LYS C . n 
C 2 290 SER 290 290  290 SER SER C . n 
C 2 291 PHE 291 291  291 PHE PHE C . n 
C 2 292 ASN 292 292  292 ASN ASN C . n 
C 2 293 LEU 293 293  293 LEU LEU C . n 
C 2 294 PRO 294 294  294 PRO PRO C . n 
C 2 295 MET 295 295  295 MET MET C . n 
C 2 296 LEU 296 296  296 LEU LEU C . n 
C 2 297 MET 297 297  297 MET MET C . n 
C 2 298 LEU 298 298  298 LEU LEU C . n 
C 2 299 GLY 299 299  299 GLY GLY C . n 
C 2 300 GLY 300 300  300 GLY GLY C . n 
C 2 301 GLY 301 301  301 GLY GLY C . n 
C 2 302 GLY 302 302  302 GLY GLY C . n 
C 2 303 TYR 303 303  303 TYR TYR C . n 
C 2 304 THR 304 304  304 THR THR C . n 
C 2 305 ILE 305 305  305 ILE ILE C . n 
C 2 306 ARG 306 306  306 ARG ARG C . n 
C 2 307 ASN 307 307  307 ASN ASN C . n 
C 2 308 VAL 308 308  308 VAL VAL C . n 
C 2 309 ALA 309 309  309 ALA ALA C . n 
C 2 310 ARG 310 310  310 ARG ARG C . n 
C 2 311 CYS 311 311  311 CYS CYS C . n 
C 2 312 TRP 312 312  312 TRP TRP C . n 
C 2 313 THR 313 313  313 THR THR C . n 
C 2 314 TYR 314 314  314 TYR TYR C . n 
C 2 315 GLU 315 315  315 GLU GLU C . n 
C 2 316 THR 316 316  316 THR THR C . n 
C 2 317 ALA 317 317  317 ALA ALA C . n 
C 2 318 VAL 318 318  318 VAL VAL C . n 
C 2 319 ALA 319 319  319 ALA ALA C . n 
C 2 320 LEU 320 320  320 LEU LEU C . n 
C 2 321 ASP 321 321  321 ASP ASP C . n 
C 2 322 THR 322 322  322 THR THR C . n 
C 2 323 GLU 323 323  323 GLU GLU C . n 
C 2 324 ILE 324 324  324 ILE ILE C . n 
C 2 325 PRO 325 325  325 PRO PRO C . n 
C 2 326 ASN 326 326  326 ASN ASN C . n 
C 2 327 GLU 327 327  327 GLU GLU C . n 
C 2 328 LEU 328 328  328 LEU LEU C . n 
C 2 329 PRO 329 329  329 PRO PRO C . n 
C 2 330 TYR 330 330  330 TYR TYR C . n 
C 2 331 ASN 331 331  331 ASN ASN C . n 
C 2 332 ASP 332 332  332 ASP ASP C . n 
C 2 333 TYR 333 333  333 TYR TYR C . n 
C 2 334 PHE 334 334  334 PHE PHE C . n 
C 2 335 GLU 335 335  335 GLU GLU C . n 
C 2 336 TYR 336 336  336 TYR TYR C . n 
C 2 337 PHE 337 337  337 PHE PHE C . n 
C 2 338 GLY 338 338  338 GLY GLY C . n 
C 2 339 PRO 339 339  339 PRO PRO C . n 
C 2 340 ASP 340 340  340 ASP ASP C . n 
C 2 341 PHE 341 341  341 PHE PHE C . n 
C 2 342 LYS 342 342  342 LYS LYS C . n 
C 2 343 LEU 343 343  343 LEU LEU C . n 
C 2 344 HIS 344 344  344 HIS HIS C . n 
C 2 345 ILE 345 345  345 ILE ILE C . n 
C 2 346 SER 346 346  346 SER SER C . n 
C 2 347 PRO 347 347  347 PRO PRO C . n 
C 2 348 SER 348 348  348 SER SER C . n 
C 2 349 ASN 349 349  349 ASN ASN C . n 
C 2 350 MET 350 350  350 MET MET C . n 
C 2 351 THR 351 351  351 THR THR C . n 
C 2 352 ASN 352 352  352 ASN ASN C . n 
C 2 353 GLN 353 353  353 GLN GLN C . n 
C 2 354 ASN 354 354  354 ASN ASN C . n 
C 2 355 THR 355 355  355 THR THR C . n 
C 2 356 ASN 356 356  356 ASN ASN C . n 
C 2 357 GLU 357 357  357 GLU GLU C . n 
C 2 358 TYR 358 358  358 TYR TYR C . n 
C 2 359 LEU 359 359  359 LEU LEU C . n 
C 2 360 GLU 360 360  360 GLU GLU C . n 
C 2 361 LYS 361 361  361 LYS LYS C . n 
C 2 362 ILE 362 362  362 ILE ILE C . n 
C 2 363 LYS 363 363  363 LYS LYS C . n 
C 2 364 GLN 364 364  364 GLN GLN C . n 
C 2 365 ARG 365 365  365 ARG ARG C . n 
C 2 366 LEU 366 366  366 LEU LEU C . n 
C 2 367 PHE 367 367  367 PHE PHE C . n 
C 2 368 GLU 368 368  368 GLU GLU C . n 
C 2 369 ASN 369 369  369 ASN ASN C . n 
C 2 370 LEU 370 370  370 LEU LEU C . n 
C 2 371 ARG 371 371  371 ARG ARG C . n 
C 2 372 MET 372 372  372 MET MET C . n 
C 2 373 LEU 373 373  373 LEU LEU C . n 
C 2 374 PRO 374 374  374 PRO PRO C . n 
C 2 375 HIS 375 375  375 HIS HIS C . n 
C 2 376 ALA 376 376  376 ALA ALA C . n 
C 2 377 PRO 377 377  ?   ?   ?   C . n 
C 2 378 GLY 378 378  ?   ?   ?   C . n 
C 2 379 VAL 379 379  ?   ?   ?   C . n 
C 2 380 GLN 380 380  ?   ?   ?   C . n 
C 2 381 MET 381 381  ?   ?   ?   C . n 
C 2 382 GLN 382 382  ?   ?   ?   C . n 
C 2 383 ALA 383 383  ?   ?   ?   C . n 
C 2 384 ILE 384 384  ?   ?   ?   C . n 
C 2 385 PRO 385 385  ?   ?   ?   C . n 
C 2 386 GLU 386 386  ?   ?   ?   C . n 
C 2 387 ASP 387 387  ?   ?   ?   C . n 
C 2 388 ALA 388 388  ?   ?   ?   C . n 
C 2 389 ILE 389 389  ?   ?   ?   C . n 
C 2 390 PRO 390 390  ?   ?   ?   C . n 
C 2 391 GLU 391 391  ?   ?   ?   C . n 
C 2 392 GLU 392 392  ?   ?   ?   C . n 
C 2 393 SER 393 393  ?   ?   ?   C . n 
C 2 394 GLY 394 394  ?   ?   ?   C . n 
C 2 395 ASP 395 395  ?   ?   ?   C . n 
C 2 396 GLU 396 396  ?   ?   ?   C . n 
C 2 397 ASP 397 397  ?   ?   ?   C . n 
C 2 398 GLU 398 398  ?   ?   ?   C . n 
C 2 399 ASP 399 399  ?   ?   ?   C . n 
C 2 400 ASP 400 400  ?   ?   ?   C . n 
C 2 401 PRO 401 401  ?   ?   ?   C . n 
C 2 402 ASP 402 402  ?   ?   ?   C . n 
C 2 403 LYS 403 403  ?   ?   ?   C . n 
C 2 404 ARG 404 404  ?   ?   ?   C . n 
C 2 405 ILE 405 405  ?   ?   ?   C . n 
C 2 406 SER 406 406  ?   ?   ?   C . n 
C 2 407 ILE 407 407  ?   ?   ?   C . n 
C 2 408 CYS 408 408  ?   ?   ?   C . n 
C 2 409 SER 409 409  ?   ?   ?   C . n 
C 2 410 SER 410 410  ?   ?   ?   C . n 
C 2 411 ASP 411 411  ?   ?   ?   C . n 
C 2 412 LYS 412 412  ?   ?   ?   C . n 
C 2 413 ARG 413 413  ?   ?   ?   C . n 
C 2 414 ILE 414 414  ?   ?   ?   C . n 
C 2 415 ALA 415 415  ?   ?   ?   C . n 
C 2 416 CYS 416 416  ?   ?   ?   C . n 
C 2 417 GLU 417 417  ?   ?   ?   C . n 
C 2 418 GLU 418 418  ?   ?   ?   C . n 
C 2 419 GLU 419 419  ?   ?   ?   C . n 
C 2 420 PHE 420 420  ?   ?   ?   C . n 
C 2 421 SER 421 421  ?   ?   ?   C . n 
C 2 422 ASP 422 422  ?   ?   ?   C . n 
C 2 423 SER 423 423  ?   ?   ?   C . n 
C 2 424 GLU 424 424  ?   ?   ?   C . n 
C 2 425 GLU 425 425  ?   ?   ?   C . n 
C 2 426 GLU 426 426  ?   ?   ?   C . n 
C 2 427 GLY 427 427  ?   ?   ?   C . n 
C 2 428 GLU 428 428  ?   ?   ?   C . n 
C 2 429 GLY 429 429  ?   ?   ?   C . n 
C 2 430 GLY 430 430  ?   ?   ?   C . n 
C 2 431 ARG 431 431  ?   ?   ?   C . n 
C 2 432 LYS 432 432  ?   ?   ?   C . n 
C 2 433 ASN 433 433  ?   ?   ?   C . n 
C 2 434 SER 434 434  ?   ?   ?   C . n 
C 2 435 SER 435 435  ?   ?   ?   C . n 
C 2 436 ASN 436 436  ?   ?   ?   C . n 
C 2 437 PHE 437 437  ?   ?   ?   C . n 
C 2 438 LYS 438 438  ?   ?   ?   C . n 
C 2 439 LYS 439 439  ?   ?   ?   C . n 
C 2 440 ALA 440 440  ?   ?   ?   C . n 
C 2 441 LYS 441 441  ?   ?   ?   C . n 
C 2 442 ARG 442 442  ?   ?   ?   C . n 
C 2 443 VAL 443 443  ?   ?   ?   C . n 
C 2 444 LYS 444 444  ?   ?   ?   C . n 
C 2 445 THR 445 445  ?   ?   ?   C . n 
C 2 446 GLU 446 446  ?   ?   ?   C . n 
C 2 447 ASP 447 447  ?   ?   ?   C . n 
C 2 448 GLU 448 448  ?   ?   ?   C . n 
C 2 449 LYS 449 449  ?   ?   ?   C . n 
C 2 450 GLU 450 450  ?   ?   ?   C . n 
C 2 451 LYS 451 451  ?   ?   ?   C . n 
C 2 452 ASP 452 452  ?   ?   ?   C . n 
C 2 453 PRO 453 453  ?   ?   ?   C . n 
C 2 454 GLU 454 454  ?   ?   ?   C . n 
C 2 455 GLU 455 455  ?   ?   ?   C . n 
C 2 456 LYS 456 456  ?   ?   ?   C . n 
C 2 457 LYS 457 457  ?   ?   ?   C . n 
C 2 458 GLU 458 458  ?   ?   ?   C . n 
C 2 459 VAL 459 459  ?   ?   ?   C . n 
C 2 460 THR 460 460  ?   ?   ?   C . n 
C 2 461 GLU 461 461  ?   ?   ?   C . n 
C 2 462 GLU 462 462  ?   ?   ?   C . n 
C 2 463 GLU 463 463  ?   ?   ?   C . n 
C 2 464 LYS 464 464  ?   ?   ?   C . n 
C 2 465 THR 465 465  ?   ?   ?   C . n 
C 2 466 LYS 466 466  ?   ?   ?   C . n 
C 2 467 GLU 467 467  ?   ?   ?   C . n 
C 2 468 GLU 468 468  ?   ?   ?   C . n 
C 2 469 LYS 469 469  ?   ?   ?   C . n 
C 2 470 PRO 470 470  ?   ?   ?   C . n 
C 2 471 GLU 471 471  ?   ?   ?   C . n 
C 2 472 ALA 472 472  ?   ?   ?   C . n 
C 2 473 LYS 473 473  ?   ?   ?   C . n 
C 2 474 GLY 474 474  ?   ?   ?   C . n 
C 2 475 VAL 475 475  ?   ?   ?   C . n 
C 2 476 LYS 476 476  ?   ?   ?   C . n 
C 2 477 GLU 477 477  ?   ?   ?   C . n 
C 2 478 GLU 478 478  ?   ?   ?   C . n 
C 2 479 VAL 479 479  ?   ?   ?   C . n 
C 2 480 LYS 480 480  ?   ?   ?   C . n 
C 2 481 LEU 481 481  ?   ?   ?   C . n 
C 2 482 ALA 482 482  ?   ?   ?   C . n 
D 3 1   MET 1   -103 ?   ?   ?   D . n 
D 3 2   PRO 2   -102 ?   ?   ?   D . n 
D 3 3   ALA 3   -101 ?   ?   ?   D . n 
D 3 4   MET 4   -100 ?   ?   ?   D . n 
D 3 5   VAL 5   -99  ?   ?   ?   D . n 
D 3 6   GLU 6   -98  ?   ?   ?   D . n 
D 3 7   LYS 7   -97  ?   ?   ?   D . n 
D 3 8   GLY 8   -96  ?   ?   ?   D . n 
D 3 9   PRO 9   -95  ?   ?   ?   D . n 
D 3 10  GLU 10  -94  ?   ?   ?   D . n 
D 3 11  VAL 11  -93  ?   ?   ?   D . n 
D 3 12  SER 12  -92  ?   ?   ?   D . n 
D 3 13  GLY 13  -91  ?   ?   ?   D . n 
D 3 14  LYS 14  -90  ?   ?   ?   D . n 
D 3 15  ARG 15  -89  ?   ?   ?   D . n 
D 3 16  ARG 16  -88  ?   ?   ?   D . n 
D 3 17  GLY 17  -87  ?   ?   ?   D . n 
D 3 18  ARG 18  -86  ?   ?   ?   D . n 
D 3 19  ASN 19  -85  ?   ?   ?   D . n 
D 3 20  ASN 20  -84  ?   ?   ?   D . n 
D 3 21  ALA 21  -83  ?   ?   ?   D . n 
D 3 22  ALA 22  -82  ?   ?   ?   D . n 
D 3 23  ALA 23  -81  ?   ?   ?   D . n 
D 3 24  SER 24  -80  ?   ?   ?   D . n 
D 3 25  ALA 25  -79  ?   ?   ?   D . n 
D 3 26  SER 26  -78  ?   ?   ?   D . n 
D 3 27  ALA 27  -77  ?   ?   ?   D . n 
D 3 28  ALA 28  -76  ?   ?   ?   D . n 
D 3 29  ALA 29  -75  ?   ?   ?   D . n 
D 3 30  ALA 30  -74  ?   ?   ?   D . n 
D 3 31  SER 31  -73  ?   ?   ?   D . n 
D 3 32  ALA 32  -72  ?   ?   ?   D . n 
D 3 33  ALA 33  -71  ?   ?   ?   D . n 
D 3 34  ALA 34  -70  ?   ?   ?   D . n 
D 3 35  SER 35  -69  ?   ?   ?   D . n 
D 3 36  ALA 36  -68  ?   ?   ?   D . n 
D 3 37  ALA 37  -67  ?   ?   ?   D . n 
D 3 38  CYS 38  -66  ?   ?   ?   D . n 
D 3 39  ALA 39  -65  ?   ?   ?   D . n 
D 3 40  SER 40  -64  ?   ?   ?   D . n 
D 3 41  PRO 41  -63  ?   ?   ?   D . n 
D 3 42  ALA 42  -62  ?   ?   ?   D . n 
D 3 43  ALA 43  -61  ?   ?   ?   D . n 
D 3 44  THR 44  -60  ?   ?   ?   D . n 
D 3 45  ALA 45  -59  ?   ?   ?   D . n 
D 3 46  ALA 46  -58  ?   ?   ?   D . n 
D 3 47  SER 47  -57  ?   ?   ?   D . n 
D 3 48  GLY 48  -56  ?   ?   ?   D . n 
D 3 49  ALA 49  -55  ?   ?   ?   D . n 
D 3 50  ALA 50  -54  ?   ?   ?   D . n 
D 3 51  ALA 51  -53  ?   ?   ?   D . n 
D 3 52  SER 52  -52  ?   ?   ?   D . n 
D 3 53  SER 53  -51  ?   ?   ?   D . n 
D 3 54  ALA 54  -50  ?   ?   ?   D . n 
D 3 55  SER 55  -49  ?   ?   ?   D . n 
D 3 56  ALA 56  -48  ?   ?   ?   D . n 
D 3 57  ALA 57  -47  ?   ?   ?   D . n 
D 3 58  ALA 58  -46  ?   ?   ?   D . n 
D 3 59  ALA 59  -45  ?   ?   ?   D . n 
D 3 60  SER 60  -44  ?   ?   ?   D . n 
D 3 61  ALA 61  -43  ?   ?   ?   D . n 
D 3 62  ALA 62  -42  ?   ?   ?   D . n 
D 3 63  ALA 63  -41  ?   ?   ?   D . n 
D 3 64  ALA 64  -40  ?   ?   ?   D . n 
D 3 65  PRO 65  -39  ?   ?   ?   D . n 
D 3 66  ASN 66  -38  ?   ?   ?   D . n 
D 3 67  ASN 67  -37  ?   ?   ?   D . n 
D 3 68  GLY 68  -36  ?   ?   ?   D . n 
D 3 69  GLN 69  -35  ?   ?   ?   D . n 
D 3 70  ASN 70  -34  ?   ?   ?   D . n 
D 3 71  LYS 71  -33  ?   ?   ?   D . n 
D 3 72  SER 72  -32  ?   ?   ?   D . n 
D 3 73  LEU 73  -31  ?   ?   ?   D . n 
D 3 74  ALA 74  -30  ?   ?   ?   D . n 
D 3 75  ALA 75  -29  ?   ?   ?   D . n 
D 3 76  ALA 76  -28  ?   ?   ?   D . n 
D 3 77  ALA 77  -27  ?   ?   ?   D . n 
D 3 78  PRO 78  -26  ?   ?   ?   D . n 
D 3 79  ASN 79  -25  ?   ?   ?   D . n 
D 3 80  GLY 80  -24  ?   ?   ?   D . n 
D 3 81  ASN 81  -23  ?   ?   ?   D . n 
D 3 82  SER 82  -22  ?   ?   ?   D . n 
D 3 83  SER 83  -21  ?   ?   ?   D . n 
D 3 84  SER 84  -20  ?   ?   ?   D . n 
D 3 85  ASN 85  -19  ?   ?   ?   D . n 
D 3 86  SER 86  -18  ?   ?   ?   D . n 
D 3 87  TRP 87  -17  ?   ?   ?   D . n 
D 3 88  GLU 88  -16  ?   ?   ?   D . n 
D 3 89  GLU 89  -15  ?   ?   ?   D . n 
D 3 90  GLY 90  -14  ?   ?   ?   D . n 
D 3 91  SER 91  -13  ?   ?   ?   D . n 
D 3 92  SER 92  -12  ?   ?   ?   D . n 
D 3 93  GLY 93  -11  ?   ?   ?   D . n 
D 3 94  SER 94  -10  ?   ?   ?   D . n 
D 3 95  SER 95  -9   ?   ?   ?   D . n 
D 3 96  SER 96  -8   ?   ?   ?   D . n 
D 3 97  ASP 97  -7   ?   ?   ?   D . n 
D 3 98  GLU 98  -6   ?   ?   ?   D . n 
D 3 99  GLU 99  -5   ?   ?   ?   D . n 
D 3 100 HIS 100 -4   ?   ?   ?   D . n 
D 3 101 GLY 101 -3   ?   ?   ?   D . n 
D 3 102 GLY 102 -2   ?   ?   ?   D . n 
D 3 103 GLY 103 -1   ?   ?   ?   D . n 
D 3 104 GLY 104 0    ?   ?   ?   D . n 
D 3 105 MET 105 1    1   MET MET D . n 
D 3 106 ARG 106 2    2   ARG ARG D . n 
D 3 107 VAL 107 3    3   VAL VAL D . n 
D 3 108 GLY 108 4    4   GLY GLY D . n 
D 3 109 PRO 109 5    5   PRO PRO D . n 
D 3 110 GLN 110 6    6   GLN GLN D . n 
D 3 111 TYR 111 7    7   TYR TYR D . n 
D 3 112 GLN 112 8    8   GLN GLN D . n 
D 3 113 ALA 113 9    9   ALA ALA D . n 
D 3 114 VAL 114 10   10  VAL VAL D . n 
D 3 115 VAL 115 11   11  VAL VAL D . n 
D 3 116 PRO 116 12   12  PRO PRO D . n 
D 3 117 ASP 117 13   13  ASP ASP D . n 
D 3 118 PHE 118 14   14  PHE PHE D . n 
D 3 119 ASP 119 15   15  ASP ASP D . n 
D 3 120 PRO 120 16   16  PRO PRO D . n 
D 3 121 ALA 121 17   17  ALA ALA D . n 
D 3 122 LYS 122 18   18  LYS LYS D . n 
D 3 123 LEU 123 19   19  LEU LEU D . n 
D 3 124 ALA 124 20   20  ALA ALA D . n 
D 3 125 ARG 125 21   21  ARG ARG D . n 
D 3 126 ARG 126 22   22  ARG ARG D . n 
D 3 127 SER 127 23   23  SER SER D . n 
D 3 128 GLN 128 24   24  GLN GLN D . n 
D 3 129 GLU 129 25   25  GLU GLU D . n 
D 3 130 ARG 130 26   26  ARG ARG D . n 
D 3 131 ASP 131 27   27  ASP ASP D . n 
D 3 132 ASN 132 28   28  ASN ASN D . n 
D 3 133 LEU 133 29   29  LEU LEU D . n 
D 3 134 GLY 134 30   30  GLY GLY D . n 
D 3 135 MET 135 31   31  MET MET D . n 
D 3 136 LEU 136 32   32  LEU LEU D . n 
D 3 137 VAL 137 33   33  VAL VAL D . n 
D 3 138 TRP 138 34   34  TRP TRP D . n 
D 3 139 SER 139 35   35  SER SER D . n 
D 3 140 PRO 140 36   36  PRO PRO D . n 
D 3 141 ASN 141 37   37  ASN ASN D . n 
D 3 142 GLN 142 38   38  GLN GLN D . n 
D 3 143 ASN 143 39   39  ASN ASN D . n 
D 3 144 LEU 144 40   40  LEU LEU D . n 
D 3 145 SER 145 41   41  SER SER D . n 
D 3 146 GLU 146 42   42  GLU GLU D . n 
D 3 147 ALA 147 43   43  ALA ALA D . n 
D 3 148 LYS 148 44   44  LYS LYS D . n 
D 3 149 LEU 149 45   45  LEU LEU D . n 
D 3 150 ASP 150 46   46  ASP ASP D . n 
D 3 151 GLU 151 47   47  GLU GLU D . n 
D 3 152 TYR 152 48   48  TYR TYR D . n 
D 3 153 ILE 153 49   49  ILE ILE D . n 
D 3 154 ALA 154 50   50  ALA ALA D . n 
D 3 155 ILE 155 51   51  ILE ILE D . n 
D 3 156 ALA 156 52   52  ALA ALA D . n 
D 3 157 LYS 157 53   53  LYS LYS D . n 
D 3 158 GLU 158 54   54  GLU GLU D . n 
D 3 159 LYS 159 55   55  LYS LYS D . n 
D 3 160 HIS 160 56   56  HIS HIS D . n 
D 3 161 GLY 161 57   57  GLY GLY D . n 
D 3 162 TYR 162 58   58  TYR TYR D . n 
D 3 163 ASN 163 59   59  ASN ASN D . n 
D 3 164 MET 164 60   60  MET MET D . n 
D 3 165 GLU 165 61   61  GLU GLU D . n 
D 3 166 GLN 166 62   62  GLN GLN D . n 
D 3 167 ALA 167 63   63  ALA ALA D . n 
D 3 168 LEU 168 64   64  LEU LEU D . n 
D 3 169 GLY 169 65   65  GLY GLY D . n 
D 3 170 MET 170 66   66  MET MET D . n 
D 3 171 LEU 171 67   67  LEU LEU D . n 
D 3 172 PHE 172 68   68  PHE PHE D . n 
D 3 173 TRP 173 69   69  TRP TRP D . n 
D 3 174 HIS 174 70   70  HIS HIS D . n 
D 3 175 LYS 175 71   71  LYS LYS D . n 
D 3 176 HIS 176 72   72  HIS HIS D . n 
D 3 177 ASN 177 73   73  ASN ASN D . n 
D 3 178 ILE 178 74   74  ILE ILE D . n 
D 3 179 GLU 179 75   75  GLU GLU D . n 
D 3 180 LYS 180 76   76  LYS LYS D . n 
D 3 181 SER 181 77   77  SER SER D . n 
D 3 182 LEU 182 78   78  LEU LEU D . n 
D 3 183 ALA 183 79   79  ALA ALA D . n 
D 3 184 ASP 184 80   80  ASP ASP D . n 
D 3 185 LEU 185 81   81  LEU LEU D . n 
D 3 186 PRO 186 82   82  PRO PRO D . n 
D 3 187 ASN 187 83   83  ASN ASN D . n 
D 3 188 PHE 188 84   84  PHE PHE D . n 
D 3 189 THR 189 85   85  THR THR D . n 
D 3 190 PRO 190 86   86  PRO PRO D . n 
D 3 191 PHE 191 87   87  PHE PHE D . n 
D 3 192 PRO 192 88   88  PRO PRO D . n 
D 3 193 ASP 193 89   89  ASP ASP D . n 
D 3 194 GLU 194 90   90  GLU GLU D . n 
D 3 195 TRP 195 91   91  TRP TRP D . n 
D 3 196 THR 196 92   92  THR THR D . n 
D 3 197 VAL 197 93   93  VAL VAL D . n 
D 3 198 GLU 198 94   94  GLU GLU D . n 
D 3 199 ASP 199 95   95  ASP ASP D . n 
D 3 200 LYS 200 96   96  LYS LYS D . n 
D 3 201 VAL 201 97   97  VAL VAL D . n 
D 3 202 LEU 202 98   98  LEU LEU D . n 
D 3 203 PHE 203 99   99  PHE PHE D . n 
D 3 204 GLU 204 100  100 GLU GLU D . n 
D 3 205 GLN 205 101  101 GLN GLN D . n 
D 3 206 ALA 206 102  102 ALA ALA D . n 
D 3 207 PHE 207 103  103 PHE PHE D . n 
D 3 208 SER 208 104  104 SER SER D . n 
D 3 209 PHE 209 105  105 PHE PHE D . n 
D 3 210 HIS 210 106  106 HIS HIS D . n 
D 3 211 GLY 211 107  107 GLY GLY D . n 
D 3 212 LYS 212 108  108 LYS LYS D . n 
D 3 213 THR 213 109  109 THR THR D . n 
D 3 214 PHE 214 110  110 PHE PHE D . n 
D 3 215 HIS 215 111  111 HIS HIS D . n 
D 3 216 ARG 216 112  112 ARG ARG D . n 
D 3 217 ILE 217 113  113 ILE ILE D . n 
D 3 218 GLN 218 114  114 GLN GLN D . n 
D 3 219 GLN 219 115  115 GLN GLN D . n 
D 3 220 MET 220 116  116 MET MET D . n 
D 3 221 LEU 221 117  117 LEU LEU D . n 
D 3 222 PRO 222 118  118 PRO PRO D . n 
D 3 223 ASP 223 119  119 ASP ASP D . n 
D 3 224 LYS 224 120  120 LYS LYS D . n 
D 3 225 SER 225 121  121 SER SER D . n 
D 3 226 ILE 226 122  122 ILE ILE D . n 
D 3 227 ALA 227 123  123 ALA ALA D . n 
D 3 228 SER 228 124  124 SER SER D . n 
D 3 229 LEU 229 125  125 LEU LEU D . n 
D 3 230 VAL 230 126  126 VAL VAL D . n 
D 3 231 LYS 231 127  127 LYS LYS D . n 
D 3 232 PHE 232 128  128 PHE PHE D . n 
D 3 233 TYR 233 129  129 TYR TYR D . n 
D 3 234 TYR 234 130  130 TYR TYR D . n 
D 3 235 SER 235 131  131 SER SER D . n 
D 3 236 TRP 236 132  132 TRP TRP D . n 
D 3 237 LYS 237 133  133 LYS LYS D . n 
D 3 238 LYS 238 134  134 LYS LYS D . n 
D 3 239 THR 239 135  135 THR THR D . n 
D 3 240 ARG 240 136  ?   ?   ?   D . n 
D 3 241 THR 241 137  ?   ?   ?   D . n 
D 3 242 LYS 242 138  ?   ?   ?   D . n 
D 3 243 THR 243 139  ?   ?   ?   D . n 
D 3 244 SER 244 140  ?   ?   ?   D . n 
D 3 245 VAL 245 141  ?   ?   ?   D . n 
D 3 246 MET 246 142  ?   ?   ?   D . n 
D 3 247 ASP 247 143  ?   ?   ?   D . n 
D 3 248 ARG 248 144  ?   ?   ?   D . n 
D 3 249 HIS 249 145  ?   ?   ?   D . n 
D 3 250 ALA 250 146  ?   ?   ?   D . n 
D 3 251 ARG 251 147  ?   ?   ?   D . n 
D 3 252 LYS 252 148  ?   ?   ?   D . n 
D 3 253 GLN 253 149  ?   ?   ?   D . n 
D 3 254 LYS 254 150  ?   ?   ?   D . n 
D 3 255 ARG 255 151  ?   ?   ?   D . n 
D 3 256 GLU 256 152  ?   ?   ?   D . n 
D 3 257 ARG 257 153  ?   ?   ?   D . n 
D 3 258 GLU 258 154  ?   ?   ?   D . n 
D 3 259 GLU 259 155  ?   ?   ?   D . n 
D 3 260 SER 260 156  ?   ?   ?   D . n 
D 3 261 GLU 261 157  ?   ?   ?   D . n 
D 3 262 ASP 262 158  ?   ?   ?   D . n 
D 3 263 GLU 263 159  ?   ?   ?   D . n 
D 3 264 LEU 264 160  ?   ?   ?   D . n 
D 3 265 GLU 265 161  ?   ?   ?   D . n 
D 3 266 GLU 266 162  ?   ?   ?   D . n 
D 3 267 ALA 267 163  ?   ?   ?   D . n 
D 3 268 ASN 268 164  ?   ?   ?   D . n 
D 3 269 GLY 269 165  ?   ?   ?   D . n 
D 3 270 ASN 270 166  ?   ?   ?   D . n 
D 3 271 ASN 271 167  ?   ?   ?   D . n 
D 3 272 PRO 272 168  ?   ?   ?   D . n 
D 3 273 ILE 273 169  ?   ?   ?   D . n 
D 3 274 ASP 274 170  ?   ?   ?   D . n 
D 3 275 ILE 275 171  ?   ?   ?   D . n 
D 3 276 GLU 276 172  ?   ?   ?   D . n 
D 3 277 VAL 277 173  ?   ?   ?   D . n 
D 3 278 ASP 278 174  ?   ?   ?   D . n 
D 3 279 GLN 279 175  ?   ?   ?   D . n 
D 3 280 ASN 280 176  ?   ?   ?   D . n 
D 3 281 LYS 281 177  ?   ?   ?   D . n 
D 3 282 GLU 282 178  ?   ?   ?   D . n 
D 3 283 SER 283 179  ?   ?   ?   D . n 
D 3 284 LYS 284 180  ?   ?   ?   D . n 
D 3 285 LYS 285 181  ?   ?   ?   D . n 
D 3 286 GLU 286 182  ?   ?   ?   D . n 
D 3 287 VAL 287 183  ?   ?   ?   D . n 
D 3 288 PRO 288 184  ?   ?   ?   D . n 
D 3 289 PRO 289 185  ?   ?   ?   D . n 
D 3 290 THR 290 186  ?   ?   ?   D . n 
D 3 291 GLU 291 187  ?   ?   ?   D . n 
D 3 292 THR 292 188  ?   ?   ?   D . n 
D 3 293 VAL 293 189  ?   ?   ?   D . n 
D 3 294 PRO 294 190  ?   ?   ?   D . n 
D 3 295 GLN 295 191  ?   ?   ?   D . n 
D 3 296 VAL 296 192  ?   ?   ?   D . n 
D 3 297 LYS 297 193  ?   ?   ?   D . n 
D 3 298 LYS 298 194  ?   ?   ?   D . n 
D 3 299 GLU 299 195  ?   ?   ?   D . n 
D 3 300 LYS 300 196  ?   ?   ?   D . n 
D 3 301 HIS 301 197  ?   ?   ?   D . n 
D 3 302 SER 302 198  ?   ?   ?   D . n 
D 3 303 THR 303 199  ?   ?   ?   D . n 
D 3 304 GLN 304 200  ?   ?   ?   D . n 
D 3 305 ALA 305 201  ?   ?   ?   D . n 
D 3 306 LYS 306 202  ?   ?   ?   D . n 
D 3 307 ASN 307 203  ?   ?   ?   D . n 
D 3 308 ARG 308 204  ?   ?   ?   D . n 
D 3 309 ALA 309 205  ?   ?   ?   D . n 
D 3 310 LYS 310 206  ?   ?   ?   D . n 
D 3 311 ARG 311 207  ?   ?   ?   D . n 
D 3 312 LYS 312 208  ?   ?   ?   D . n 
D 3 313 PRO 313 209  ?   ?   ?   D . n 
D 3 314 PRO 314 210  ?   ?   ?   D . n 
D 3 315 LYS 315 211  ?   ?   ?   D . n 
D 3 316 GLY 316 212  ?   ?   ?   D . n 
D 3 317 MET 317 213  ?   ?   ?   D . n 
D 3 318 PHE 318 214  ?   ?   ?   D . n 
D 3 319 LEU 319 215  ?   ?   ?   D . n 
D 3 320 SER 320 216  ?   ?   ?   D . n 
D 3 321 GLN 321 217  ?   ?   ?   D . n 
D 3 322 GLU 322 218  ?   ?   ?   D . n 
D 3 323 ASP 323 219  ?   ?   ?   D . n 
D 3 324 VAL 324 220  ?   ?   ?   D . n 
D 3 325 GLU 325 221  ?   ?   ?   D . n 
D 3 326 ALA 326 222  ?   ?   ?   D . n 
D 3 327 VAL 327 223  ?   ?   ?   D . n 
D 3 328 SER 328 224  ?   ?   ?   D . n 
D 3 329 ALA 329 225  ?   ?   ?   D . n 
D 3 330 ASN 330 226  ?   ?   ?   D . n 
D 3 331 ALA 331 227  ?   ?   ?   D . n 
D 3 332 THR 332 228  ?   ?   ?   D . n 
D 3 333 ALA 333 229  ?   ?   ?   D . n 
D 3 334 ALA 334 230  ?   ?   ?   D . n 
D 3 335 THR 335 231  ?   ?   ?   D . n 
D 3 336 THR 336 232  ?   ?   ?   D . n 
D 3 337 VAL 337 233  ?   ?   ?   D . n 
D 3 338 LEU 338 234  ?   ?   ?   D . n 
D 3 339 ARG 339 235  ?   ?   ?   D . n 
D 3 340 GLN 340 236  ?   ?   ?   D . n 
D 3 341 LEU 341 237  ?   ?   ?   D . n 
D 3 342 ASP 342 238  ?   ?   ?   D . n 
D 3 343 MET 343 239  ?   ?   ?   D . n 
D 3 344 GLU 344 240  ?   ?   ?   D . n 
D 3 345 LEU 345 241  ?   ?   ?   D . n 
D 3 346 VAL 346 242  ?   ?   ?   D . n 
D 3 347 SER 347 243  ?   ?   ?   D . n 
D 3 348 VAL 348 244  ?   ?   ?   D . n 
D 3 349 LYS 349 245  ?   ?   ?   D . n 
D 3 350 ARG 350 246  ?   ?   ?   D . n 
D 3 351 GLN 351 247  ?   ?   ?   D . n 
D 3 352 ILE 352 248  ?   ?   ?   D . n 
D 3 353 GLN 353 249  ?   ?   ?   D . n 
D 3 354 ASN 354 250  ?   ?   ?   D . n 
D 3 355 ILE 355 251  ?   ?   ?   D . n 
D 3 356 LYS 356 252  ?   ?   ?   D . n 
D 3 357 GLN 357 253  ?   ?   ?   D . n 
D 3 358 THR 358 254  ?   ?   ?   D . n 
D 3 359 ASN 359 255  ?   ?   ?   D . n 
D 3 360 SER 360 256  ?   ?   ?   D . n 
D 3 361 ALA 361 257  ?   ?   ?   D . n 
D 3 362 LEU 362 258  ?   ?   ?   D . n 
D 3 363 LYS 363 259  ?   ?   ?   D . n 
D 3 364 GLU 364 260  ?   ?   ?   D . n 
D 3 365 LYS 365 261  ?   ?   ?   D . n 
D 3 366 LEU 366 262  ?   ?   ?   D . n 
D 3 367 ASP 367 263  ?   ?   ?   D . n 
D 3 368 GLY 368 264  ?   ?   ?   D . n 
D 3 369 GLY 369 265  ?   ?   ?   D . n 
D 3 370 ILE 370 266  ?   ?   ?   D . n 
D 3 371 GLU 371 267  ?   ?   ?   D . n 
D 3 372 PRO 372 268  ?   ?   ?   D . n 
D 3 373 TYR 373 269  ?   ?   ?   D . n 
D 3 374 ARG 374 270  ?   ?   ?   D . n 
D 3 375 LEU 375 271  ?   ?   ?   D . n 
D 3 376 PRO 376 272  ?   ?   ?   D . n 
D 3 377 GLU 377 273  ?   ?   ?   D . n 
D 3 378 VAL 378 274  ?   ?   ?   D . n 
D 3 379 ILE 379 275  ?   ?   ?   D . n 
D 3 380 GLN 380 276  ?   ?   ?   D . n 
D 3 381 LYS 381 277  ?   ?   ?   D . n 
D 3 382 CYS 382 278  ?   ?   ?   D . n 
D 3 383 ASN 383 279  ?   ?   ?   D . n 
D 3 384 ALA 384 280  ?   ?   ?   D . n 
D 3 385 ARG 385 281  ?   ?   ?   D . n 
D 3 386 TRP 386 282  ?   ?   ?   D . n 
D 3 387 THR 387 283  ?   ?   ?   D . n 
D 3 388 THR 388 284  ?   ?   ?   D . n 
D 3 389 GLU 389 285  ?   ?   ?   D . n 
D 3 390 GLU 390 286  ?   ?   ?   D . n 
D 3 391 GLN 391 287  ?   ?   ?   D . n 
D 3 392 LEU 392 288  ?   ?   ?   D . n 
D 3 393 LEU 393 289  ?   ?   ?   D . n 
D 3 394 ALA 394 290  ?   ?   ?   D . n 
D 3 395 VAL 395 291  ?   ?   ?   D . n 
D 3 396 GLN 396 292  ?   ?   ?   D . n 
D 3 397 ALA 397 293  ?   ?   ?   D . n 
D 3 398 ILE 398 294  ?   ?   ?   D . n 
D 3 399 ARG 399 295  ?   ?   ?   D . n 
D 3 400 LYS 400 296  ?   ?   ?   D . n 
D 3 401 TYR 401 297  ?   ?   ?   D . n 
D 3 402 GLY 402 298  ?   ?   ?   D . n 
D 3 403 ARG 403 299  ?   ?   ?   D . n 
D 3 404 ASP 404 300  ?   ?   ?   D . n 
D 3 405 PHE 405 301  ?   ?   ?   D . n 
D 3 406 GLN 406 302  ?   ?   ?   D . n 
D 3 407 ALA 407 303  ?   ?   ?   D . n 
D 3 408 ILE 408 304  ?   ?   ?   D . n 
D 3 409 SER 409 305  ?   ?   ?   D . n 
D 3 410 ASP 410 306  ?   ?   ?   D . n 
D 3 411 VAL 411 307  ?   ?   ?   D . n 
D 3 412 ILE 412 308  ?   ?   ?   D . n 
D 3 413 GLY 413 309  ?   ?   ?   D . n 
D 3 414 ASN 414 310  ?   ?   ?   D . n 
D 3 415 LYS 415 311  ?   ?   ?   D . n 
D 3 416 SER 416 312  ?   ?   ?   D . n 
D 3 417 VAL 417 313  ?   ?   ?   D . n 
D 3 418 VAL 418 314  ?   ?   ?   D . n 
D 3 419 GLN 419 315  ?   ?   ?   D . n 
D 3 420 VAL 420 316  ?   ?   ?   D . n 
D 3 421 LYS 421 317  ?   ?   ?   D . n 
D 3 422 ASN 422 318  ?   ?   ?   D . n 
D 3 423 PHE 423 319  ?   ?   ?   D . n 
D 3 424 PHE 424 320  ?   ?   ?   D . n 
D 3 425 VAL 425 321  ?   ?   ?   D . n 
D 3 426 ASN 426 322  ?   ?   ?   D . n 
D 3 427 TYR 427 323  ?   ?   ?   D . n 
D 3 428 ARG 428 324  ?   ?   ?   D . n 
D 3 429 ARG 429 325  ?   ?   ?   D . n 
D 3 430 ARG 430 326  ?   ?   ?   D . n 
D 3 431 PHE 431 327  ?   ?   ?   D . n 
D 3 432 ASN 432 328  ?   ?   ?   D . n 
D 3 433 ILE 433 329  ?   ?   ?   D . n 
D 3 434 ASP 434 330  ?   ?   ?   D . n 
D 3 435 GLU 435 331  ?   ?   ?   D . n 
D 3 436 VAL 436 332  ?   ?   ?   D . n 
D 3 437 LEU 437 333  ?   ?   ?   D . n 
D 3 438 GLN 438 334  ?   ?   ?   D . n 
D 3 439 GLU 439 335  ?   ?   ?   D . n 
D 3 440 TRP 440 336  ?   ?   ?   D . n 
D 3 441 GLU 441 337  ?   ?   ?   D . n 
D 3 442 ALA 442 338  ?   ?   ?   D . n 
D 3 443 GLU 443 339  ?   ?   ?   D . n 
D 3 444 HIS 444 340  ?   ?   ?   D . n 
D 3 445 GLY 445 341  ?   ?   ?   D . n 
D 3 446 LYS 446 342  ?   ?   ?   D . n 
D 3 447 GLU 447 343  ?   ?   ?   D . n 
D 3 448 GLU 448 344  ?   ?   ?   D . n 
D 3 449 THR 449 345  ?   ?   ?   D . n 
D 3 450 ASN 450 346  ?   ?   ?   D . n 
D 3 451 GLY 451 347  ?   ?   ?   D . n 
D 3 452 PRO 452 348  ?   ?   ?   D . n 
D 3 453 SER 453 349  ?   ?   ?   D . n 
D 3 454 ASN 454 350  ?   ?   ?   D . n 
D 3 455 GLN 455 351  ?   ?   ?   D . n 
D 3 456 LYS 456 352  ?   ?   ?   D . n 
D 3 457 PRO 457 353  ?   ?   ?   D . n 
D 3 458 VAL 458 354  ?   ?   ?   D . n 
D 3 459 LYS 459 355  ?   ?   ?   D . n 
D 3 460 SER 460 356  ?   ?   ?   D . n 
D 3 461 PRO 461 357  ?   ?   ?   D . n 
D 3 462 ASP 462 358  ?   ?   ?   D . n 
D 3 463 ASN 463 359  ?   ?   ?   D . n 
D 3 464 SER 464 360  ?   ?   ?   D . n 
D 3 465 ILE 465 361  ?   ?   ?   D . n 
D 3 466 LYS 466 362  ?   ?   ?   D . n 
D 3 467 MET 467 363  ?   ?   ?   D . n 
D 3 468 PRO 468 364  ?   ?   ?   D . n 
D 3 469 GLU 469 365  ?   ?   ?   D . n 
D 3 470 GLU 470 366  ?   ?   ?   D . n 
D 3 471 GLU 471 367  ?   ?   ?   D . n 
D 3 472 ASP 472 368  ?   ?   ?   D . n 
D 3 473 GLU 473 369  ?   ?   ?   D . n 
D 3 474 ALA 474 370  ?   ?   ?   D . n 
D 3 475 PRO 475 371  ?   ?   ?   D . n 
D 3 476 VAL 476 372  ?   ?   ?   D . n 
D 3 477 LEU 477 373  ?   ?   ?   D . n 
D 3 478 ASP 478 374  ?   ?   ?   D . n 
D 3 479 VAL 479 375  ?   ?   ?   D . n 
D 3 480 ARG 480 376  ?   ?   ?   D . n 
D 3 481 TYR 481 377  ?   ?   ?   D . n 
D 3 482 ALA 482 378  ?   ?   ?   D . n 
D 3 483 SER 483 379  ?   ?   ?   D . n 
D 3 484 ALA 484 380  ?   ?   ?   D . n 
D 3 485 SER 485 381  ?   ?   ?   D . n 
# 
loop_
_pdbx_entity_instance_feature.ordinal 
_pdbx_entity_instance_feature.comp_id 
_pdbx_entity_instance_feature.asym_id 
_pdbx_entity_instance_feature.seq_num 
_pdbx_entity_instance_feature.auth_comp_id 
_pdbx_entity_instance_feature.auth_asym_id 
_pdbx_entity_instance_feature.auth_seq_num 
_pdbx_entity_instance_feature.feature_type 
_pdbx_entity_instance_feature.details 
1 IHP ? ? IHP ? ? 'SUBJECT OF INVESTIGATION' ? 
2 ZN  ? ? ZN  ? ? 'SUBJECT OF INVESTIGATION' ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
E 4 ZN  1 600 600 ZN  ZN  C . 
F 5 IHP 1 701 701 IHP IHP D . 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8VPQ 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8VPQ 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8VPQ 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               ? 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8VPQ 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            . 
_refine.ls_d_res_low                             ? 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.003 ? 12365 ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.560 ? 16759 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 3.183 ? 7345  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.043 ? 1834  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.004 ? 2149  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     8VPQ 
_struct.title                        'The structure of LSD1-CoREST-HDAC1 in complex with KBTBD4IPR310delinsTTYML' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8VPQ 
_struct_keywords.text            'protein degradation, E3 ligase, Neo-substrate, cancer mutation, LIGASE' 
_struct_keywords.pdbx_keywords   LIGASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 2 ? 
D N N 3 ? 
E N N 4 ? 
F N N 5 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP KBTB4_HUMAN Q9NVX7 Q9NVX7-2 1 
;MKGGNADSWQREKLASMESPEEPGASMDENYFVNYTFKDRSHSGRVAQGIMKLCLEEELFADVTISVEGREFQLHRLVLS
AQSCFFRSMFTSNLKEAHNRVIVLQDVSESVFQLLVDYIYHGTVKLRAEELQEIYEVSDMYQLTSLFEECSRFLARTVQV
GNCLQVMWLADRHSDPELYTAAKHCAKTHLAQLQNTEEFLHLPHRLLTDIISDGVPCSQNPTEAIEAWINFNKEEREAFA
ESLRTSLKEIGENVHIYLIGKESSRTHSLAVSLHCAEDDSISVSGQNSLCHQITAACKHGGDLYVVGGSIPRRMWKCNNA
TVDWEWCAPLPRDRLQHTLVSVPGKDAIYSLGGKTLQDTLSNAVIYYRVGDNVWTETTQLEVAVSGAAGANLNGIIYLLG
GEENDLDFFTKPSRLIQCFDTETDKCHVKPYVLPFAGRMHAAVHKDLVFIVAEGDSLVCYNPLLDSFTRLCLPEAWSSAP
SLWKIASCNGSIYVFRDRYKKGDANTYKLDPATSAVTVTRGIKVLLTNLQFVLA
;
1 
2 UNP HDAC1_HUMAN Q13547 ?        2 
;MAQTQGTRRKVCYYYDGDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYHSDDYIKFLRSIR
PDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVASAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAI
LELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAI
FKPVMSKVMEMFQPSAVVLQCGSDSLSGDRLGCFNLTIKGHAKCVEFVKSFNLPMLMLGGGGYTIRNVARCWTYETAVAL
DTEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTNEYLEKIKQRLFENLRMLPHAPGVQMQAIPEDAIPEESGDEDEDD
PDKRISICSSDKRIACEEEFSDSEEEGEGGRKNSSNFKKAKRVKTEDEKEKDPEEKKEVTEEEKTKEEKPEAKGVKEEVK
LA
;
1 
3 UNP RCOR1_HUMAN Q9UKL0 ?        3 
;MPAMVEKGPEVSGKRRGRNNAAASASAAAASAAASAACASPAATAASGAAASSASAAAASAAAAPNNGQNKSLAAAAPNG
NSSSNSWEEGSSGSSSDEEHGGGGMRVGPQYQAVVPDFDPAKLARRSQERDNLGMLVWSPNQNLSEAKLDEYIAIAKEKH
GYNMEQALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKTFHRIQQMLPDKSIASLVKFYYSWKKTR
TKTSVMDRHARKQKREREESEDELEEANGNNPIDIEVDQNKESKKEVPPTETVPQVKKEKHSTQAKNRAKRKPPKGMFLS
QEDVEAVSANATAATTVLRQLDMELVSVKRQIQNIKQTNSALKEKLDGGIEPYRLPEVIQKCNARWTTEEQLLAVQAIRK
YGRDFQAISDVIGNKSVVQVKNFFVNYRRRFNIDEVLQEWEAEHGKEETNGPSNQKPVKSPDNSIKMPEEEDEAPVLDVR
YASAS
;
1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8VPQ A 1 ? 536 ? Q9NVX7 1 ? 534 ? 1    536 
2 1 8VPQ B 1 ? 536 ? Q9NVX7 1 ? 534 ? 1    536 
3 2 8VPQ C 1 ? 482 ? Q13547 1 ? 482 ? 1    482 
4 3 8VPQ D 1 ? 485 ? Q9UKL0 1 ? 485 ? -103 381 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8VPQ THR A 310 ? UNP Q9NVX7 ILE 310 conflict  310 1  
1 8VPQ THR A 311 ? UNP Q9NVX7 PRO 311 conflict  311 2  
1 8VPQ TYR A 312 ? UNP Q9NVX7 ARG 312 conflict  312 3  
1 8VPQ MET A 313 ? UNP Q9NVX7 ?   ?   insertion 313 4  
1 8VPQ LEU A 314 ? UNP Q9NVX7 ?   ?   insertion 314 5  
2 8VPQ THR B 310 ? UNP Q9NVX7 ILE 310 conflict  310 6  
2 8VPQ THR B 311 ? UNP Q9NVX7 PRO 311 conflict  311 7  
2 8VPQ TYR B 312 ? UNP Q9NVX7 ARG 312 conflict  312 8  
2 8VPQ MET B 313 ? UNP Q9NVX7 ?   ?   insertion 313 9  
2 8VPQ LEU B 314 ? UNP Q9NVX7 ?   ?   insertion 314 10 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   tetrameric 
_pdbx_struct_assembly.oligomeric_count     4 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 41  ? CYS A 54  ? SER A 41  CYS A 54  1 ? 14 
HELX_P HELX_P2  AA2 HIS A 75  ? SER A 83  ? HIS A 75  SER A 83  1 ? 9  
HELX_P HELX_P3  AA3 CYS A 84  ? PHE A 90  ? CYS A 84  PHE A 90  1 ? 7  
HELX_P HELX_P4  AA4 VAL A 111 ? TYR A 120 ? VAL A 111 TYR A 120 1 ? 10 
HELX_P HELX_P5  AA5 GLU A 130 ? TYR A 141 ? GLU A 130 TYR A 141 1 ? 12 
HELX_P HELX_P6  AA6 LEU A 143 ? ARG A 156 ? LEU A 143 ARG A 156 1 ? 14 
HELX_P HELX_P7  AA7 GLN A 159 ? ASN A 162 ? GLN A 159 ASN A 162 5 ? 4  
HELX_P HELX_P8  AA8 CYS A 163 ? HIS A 173 ? CYS A 163 HIS A 173 1 ? 11 
HELX_P HELX_P9  AA9 ASP A 175 ? HIS A 189 ? ASP A 175 HIS A 189 1 ? 15 
HELX_P HELX_P10 AB1 PRO A 203 ? SER A 212 ? PRO A 203 SER A 212 1 ? 10 
HELX_P HELX_P11 AB2 PRO A 216 ? GLN A 219 ? PRO A 216 GLN A 219 5 ? 4  
HELX_P HELX_P12 AB3 ASN A 220 ? ASN A 230 ? ASN A 220 ASN A 230 1 ? 11 
HELX_P HELX_P13 AB4 PHE A 239 ? ARG A 244 ? PHE A 239 ARG A 244 1 ? 6  
HELX_P HELX_P14 AB5 SER B 41  ? CYS B 54  ? SER B 41  CYS B 54  1 ? 14 
HELX_P HELX_P15 AB6 HIS B 75  ? ALA B 81  ? HIS B 75  ALA B 81  1 ? 7  
HELX_P HELX_P16 AB7 SER B 83  ? THR B 91  ? SER B 83  THR B 91  1 ? 9  
HELX_P HELX_P17 AB8 VAL B 111 ? TYR B 120 ? VAL B 111 TYR B 120 1 ? 10 
HELX_P HELX_P18 AB9 LEU B 131 ? GLN B 142 ? LEU B 131 GLN B 142 1 ? 12 
HELX_P HELX_P19 AC1 LEU B 143 ? THR B 157 ? LEU B 143 THR B 157 1 ? 15 
HELX_P HELX_P20 AC2 ASN B 162 ? ALA B 170 ? ASN B 162 ALA B 170 1 ? 9  
HELX_P HELX_P21 AC3 ASP B 175 ? THR B 188 ? ASP B 175 THR B 188 1 ? 14 
HELX_P HELX_P22 AC4 LEU B 190 ? GLN B 194 ? LEU B 190 GLN B 194 5 ? 5  
HELX_P HELX_P23 AC5 PRO B 203 ? SER B 212 ? PRO B 203 SER B 212 1 ? 10 
HELX_P HELX_P24 AC6 PRO B 216 ? ASN B 220 ? PRO B 216 ASN B 220 5 ? 5  
HELX_P HELX_P25 AC7 PRO B 221 ? ASN B 230 ? PRO B 221 ASN B 230 1 ? 10 
HELX_P HELX_P26 AC8 ASN B 232 ? GLU B 237 ? ASN B 232 GLU B 237 1 ? 6  
HELX_P HELX_P27 AC9 ALA B 238 ? ALA B 240 ? ALA B 238 ALA B 240 5 ? 3  
HELX_P HELX_P28 AD1 ASP C 18  ? TYR C 22  ? ASP C 18  TYR C 22  5 ? 5  
HELX_P HELX_P29 AD2 PRO C 32  ? LEU C 43  ? PRO C 32  LEU C 43  1 ? 12 
HELX_P HELX_P30 AD3 SER C 69  ? SER C 78  ? SER C 69  SER C 78  1 ? 10 
HELX_P HELX_P31 AD4 SER C 88  ? PHE C 94  ? SER C 88  PHE C 94  1 ? 7  
HELX_P HELX_P32 AD5 LEU C 106 ? ASN C 125 ? LEU C 106 ASN C 125 1 ? 20 
HELX_P HELX_P33 AD6 ASN C 154 ? LEU C 164 ? ASN C 154 LEU C 164 1 ? 11 
HELX_P HELX_P34 AD7 GLY C 180 ? PHE C 187 ? GLY C 180 PHE C 187 1 ? 8  
HELX_P HELX_P35 AD8 ASP C 233 ? GLN C 253 ? ASP C 233 GLN C 253 1 ? 21 
HELX_P HELX_P36 AD9 THR C 277 ? SER C 290 ? THR C 277 SER C 290 1 ? 14 
HELX_P HELX_P37 AE1 THR C 304 ? LEU C 320 ? THR C 304 LEU C 320 1 ? 17 
HELX_P HELX_P38 AE2 ASN C 356 ? ARG C 371 ? ASN C 356 ARG C 371 1 ? 16 
HELX_P HELX_P39 AE3 ASP D 119 ? LEU D 123 ? ASP D 15  LEU D 19  5 ? 5  
HELX_P HELX_P40 AE4 ALA D 124 ? GLU D 129 ? ALA D 20  GLU D 25  5 ? 6  
HELX_P HELX_P41 AE5 SER D 145 ? LYS D 159 ? SER D 41  LYS D 55  1 ? 15 
HELX_P HELX_P42 AE6 GLU D 165 ? TRP D 173 ? GLU D 61  TRP D 69  1 ? 9  
HELX_P HELX_P43 AE7 ASN D 177 ? ASP D 184 ? ASN D 73  ASP D 80  1 ? 8  
HELX_P HELX_P44 AE8 THR D 196 ? HIS D 210 ? THR D 92  HIS D 106 1 ? 15 
HELX_P HELX_P45 AE9 THR D 213 ? GLN D 218 ? THR D 109 GLN D 114 1 ? 6  
HELX_P HELX_P46 AF1 ILE D 226 ? SER D 235 ? ILE D 122 SER D 131 1 ? 10 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
metalc1 metalc ? ? C ASP 176 OD1 ? ? ? 1_555 E ZN . ZN ? ? C ASP 176 C ZN 600 1_555 ? ? ? ? ? ? ? 2.353 ? ? 
metalc2 metalc ? ? C ASP 176 OD2 ? ? ? 1_555 E ZN . ZN ? ? C ASP 176 C ZN 600 1_555 ? ? ? ? ? ? ? 2.036 ? ? 
metalc3 metalc ? ? C HIS 178 ND1 ? ? ? 1_555 E ZN . ZN ? ? C HIS 178 C ZN 600 1_555 ? ? ? ? ? ? ? 2.351 ? ? 
# 
_struct_conn_type.id          metalc 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1 OD1 ? C ASP 176 ? C ASP 176 ? 1_555 ZN ? E ZN . ? C ZN 600 ? 1_555 OD2 ? C ASP 176 ? C ASP 176 ? 1_555 59.2  ? 
2 OD1 ? C ASP 176 ? C ASP 176 ? 1_555 ZN ? E ZN . ? C ZN 600 ? 1_555 ND1 ? C HIS 178 ? C HIS 178 ? 1_555 113.6 ? 
3 OD2 ? C ASP 176 ? C ASP 176 ? 1_555 ZN ? E ZN . ? C ZN 600 ? 1_555 ND1 ? C HIS 178 ? C HIS 178 ? 1_555 130.6 ? 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 LEU 408 A . ? LEU 408 A ASP 409 A ? ASP 409 A 1 0.77  
2 PHE 205 C . ? PHE 205 C PRO 206 C ? PRO 206 C 1 -2.21 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 5 ? 
AA2 ? 2 ? 
AA3 ? 3 ? 
AA4 ? 2 ? 
AA5 ? 4 ? 
AA6 ? 4 ? 
AA7 ? 3 ? 
AA8 ? 2 ? 
AA9 ? 4 ? 
AB1 ? 2 ? 
AB2 ? 3 ? 
AB3 ? 4 ? 
AB4 ? 3 ? 
AB5 ? 3 ? 
AB6 ? 3 ? 
AB7 ? 4 ? 
AB8 ? 3 ? 
AB9 ? 2 ? 
AC1 ? 3 ? 
AC2 ? 9 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? parallel      
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA1 4 5 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? parallel      
AA4 1 2 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA6 3 4 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB2 1 2 ? anti-parallel 
AB2 2 3 ? anti-parallel 
AB3 1 2 ? anti-parallel 
AB3 2 3 ? anti-parallel 
AB3 3 4 ? anti-parallel 
AB4 1 2 ? anti-parallel 
AB4 2 3 ? parallel      
AB5 1 2 ? anti-parallel 
AB5 2 3 ? anti-parallel 
AB6 1 2 ? anti-parallel 
AB6 2 3 ? anti-parallel 
AB7 1 2 ? anti-parallel 
AB7 2 3 ? anti-parallel 
AB7 3 4 ? anti-parallel 
AB8 1 2 ? anti-parallel 
AB8 2 3 ? anti-parallel 
AB9 1 2 ? anti-parallel 
AC1 1 2 ? anti-parallel 
AC1 2 3 ? anti-parallel 
AC2 1 2 ? parallel      
AC2 2 3 ? parallel      
AC2 3 4 ? parallel      
AC2 4 5 ? parallel      
AC2 5 6 ? parallel      
AC2 6 7 ? parallel      
AC2 7 8 ? parallel      
AC2 8 9 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ALA A 25  ? SER A 26  ? ALA A 25  SER A 26  
AA1 2 SER B 468 ? THR B 470 ? SER B 468 THR B 470 
AA1 3 VAL B 460 ? ASN B 463 ? VAL B 460 ASN B 463 
AA1 4 LEU B 449 ? VAL B 453 ? LEU B 449 VAL B 453 
AA1 5 HIS B 442 ? HIS B 446 ? HIS B 442 HIS B 446 
AA2 1 ASN A 34  ? LYS A 38  ? ASN A 34  LYS A 38  
AA2 2 THR B 123 ? ARG B 127 ? THR B 123 ARG B 127 
AA3 1 ARG A 70  ? LEU A 74  ? ARG A 70  LEU A 74  
AA3 2 VAL A 63  ? VAL A 67  ? VAL A 63  VAL A 67  
AA3 3 VAL A 101 ? LEU A 104 ? VAL A 101 LEU A 104 
AA4 1 THR A 123 ? ARG A 127 ? THR A 123 ARG A 127 
AA4 2 ASN B 34  ? LYS B 38  ? ASN B 34  LYS B 38  
AA5 1 SER A 280 ? VAL A 283 ? SER A 280 VAL A 283 
AA5 2 VAL A 271 ? ALA A 276 ? VAL A 271 ALA A 276 
AA5 3 HIS A 255 ? LYS A 261 ? HIS A 255 LYS A 261 
AA5 4 ASN A 530 ? LEU A 535 ? ASN A 530 LEU A 535 
AA6 1 ALA A 295 ? HIS A 299 ? ALA A 295 HIS A 299 
AA6 2 ASP A 302 ? VAL A 306 ? ASP A 302 VAL A 306 
AA6 3 TRP A 317 ? CYS A 319 ? TRP A 317 CYS A 319 
AA6 4 TRP A 326 ? TRP A 328 ? TRP A 326 TRP A 328 
AA7 1 THR A 340 ? VAL A 344 ? THR A 340 VAL A 344 
AA7 2 ALA A 349 ? LEU A 353 ? ALA A 349 LEU A 353 
AA7 3 ILE A 367 ? ARG A 370 ? ILE A 367 ARG A 370 
AA8 1 GLY A 355 ? LYS A 356 ? GLY A 355 LYS A 356 
AA8 2 LEU A 362 ? SER A 363 ? LEU A 362 SER A 363 
AA9 1 ALA A 390 ? LEU A 394 ? ALA A 390 LEU A 394 
AA9 2 ILE A 397 ? LEU A 401 ? ILE A 397 LEU A 401 
AA9 3 ILE A 418 ? ASP A 422 ? ILE A 418 ASP A 422 
AA9 4 LYS A 427 ? VAL A 430 ? LYS A 427 VAL A 430 
AB1 1 GLU A 404 ? ASN A 406 ? GLU A 404 ASN A 406 
AB1 2 THR A 412 ? PRO A 414 ? THR A 412 PRO A 414 
AB2 1 HIS A 442 ? HIS A 446 ? HIS A 442 HIS A 446 
AB2 2 LEU A 449 ? VAL A 453 ? LEU A 449 VAL A 453 
AB2 3 VAL A 460 ? TYR A 462 ? VAL A 460 TYR A 462 
AB3 1 TRP A 485 ? SER A 489 ? TRP A 485 SER A 489 
AB3 2 ILE A 494 ? ARG A 498 ? ILE A 494 ARG A 498 
AB3 3 THR A 508 ? ASP A 512 ? THR A 508 ASP A 512 
AB3 4 ALA A 517 ? VAL A 520 ? ALA A 517 VAL A 520 
AB4 1 ARG B 70  ? LEU B 74  ? ARG B 70  LEU B 74  
AB4 2 VAL B 63  ? VAL B 67  ? VAL B 63  VAL B 67  
AB4 3 VAL B 101 ? LEU B 104 ? VAL B 101 LEU B 104 
AB5 1 SER B 268 ? VAL B 271 ? SER B 268 VAL B 271 
AB5 2 LEU B 258 ? LYS B 261 ? LEU B 258 LYS B 261 
AB5 3 LEU B 531 ? VAL B 534 ? LEU B 531 VAL B 534 
AB6 1 ALA B 295 ? HIS B 299 ? ALA B 295 HIS B 299 
AB6 2 ASP B 302 ? VAL B 306 ? ASP B 302 VAL B 306 
AB6 3 MET B 316 ? CYS B 319 ? MET B 316 CYS B 319 
AB7 1 THR B 340 ? VAL B 342 ? THR B 340 VAL B 342 
AB7 2 ILE B 350 ? LEU B 353 ? ILE B 350 LEU B 353 
AB7 3 ILE B 367 ? TYR B 369 ? ILE B 367 TYR B 369 
AB7 4 TRP B 376 ? GLU B 378 ? TRP B 376 GLU B 378 
AB8 1 ALA B 390 ? LEU B 394 ? ALA B 390 LEU B 394 
AB8 2 ILE B 397 ? LEU B 401 ? ILE B 397 LEU B 401 
AB8 3 ILE B 418 ? PHE B 421 ? ILE B 418 PHE B 421 
AB9 1 GLU B 405 ? ASN B 406 ? GLU B 405 ASN B 406 
AB9 2 THR B 412 ? LYS B 413 ? THR B 412 LYS B 413 
AC1 1 LYS B 486 ? ALA B 488 ? LYS B 486 ALA B 488 
AC1 2 ILE B 494 ? PHE B 497 ? ILE B 494 PHE B 497 
AC1 3 TYR B 509 ? LEU B 511 ? TYR B 509 LEU B 511 
AC2 1 ALA C 223 ? LEU C 228 ? ALA C 223 LEU C 228 
AC2 2 VAL C 193 ? LYS C 200 ? VAL C 193 LYS C 200 
AC2 3 VAL C 170 ? ASP C 174 ? VAL C 170 ASP C 174 
AC2 4 ALA C 256 ? GLN C 260 ? ALA C 256 GLN C 260 
AC2 5 MET C 295 ? LEU C 298 ? MET C 295 LEU C 298 
AC2 6 ILE C 131 ? ASN C 134 ? ILE C 131 ASN C 134 
AC2 7 VAL C 11  ? TYR C 14  ? VAL C 11  TYR C 14  
AC2 8 GLU C 52  ? ARG C 55  ? GLU C 52  ARG C 55  
AC2 9 MET D 135 ? LEU D 136 ? MET D 31  LEU D 32  
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O SER A 26  ? O SER A 26  N PHE B 469 ? N PHE B 469 
AA1 2 3 O SER B 468 ? O SER B 468 N ASN B 463 ? N ASN B 463 
AA1 3 4 O VAL B 460 ? O VAL B 460 N ILE B 452 ? N ILE B 452 
AA1 4 5 N LEU B 449 ? N LEU B 449 O HIS B 446 ? O HIS B 446 
AA2 1 2 N PHE A 37  ? N PHE A 37  O VAL B 124 ? O VAL B 124 
AA3 1 2 O ARG A 70  ? O ARG A 70  N VAL A 67  ? N VAL A 67  
AA3 2 3 N SER A 66  ? N SER A 66  O ILE A 102 ? O ILE A 102 
AA4 1 2 N VAL A 124 ? N VAL A 124 O PHE B 37  ? O PHE B 37  
AA5 1 2 O SER A 282 ? O SER A 282 N HIS A 274 ? N HIS A 274 
AA5 2 3 O VAL A 271 ? O VAL A 271 N LEU A 258 ? N LEU A 258 
AA5 3 4 N TYR A 257 ? N TYR A 257 O LEU A 535 ? O LEU A 535 
AA6 1 2 N ALA A 295 ? N ALA A 295 O VAL A 306 ? O VAL A 306 
AA6 2 3 N VAL A 305 ? N VAL A 305 O TRP A 317 ? O TRP A 317 
AA6 3 4 N LYS A 318 ? N LYS A 318 O GLU A 327 ? O GLU A 327 
AA7 1 2 N VAL A 342 ? N VAL A 342 O TYR A 351 ? O TYR A 351 
AA7 2 3 N SER A 352 ? N SER A 352 O ILE A 367 ? O ILE A 367 
AA8 1 2 N GLY A 355 ? N GLY A 355 O SER A 363 ? O SER A 363 
AA9 1 2 N LEU A 394 ? N LEU A 394 O ILE A 397 ? O ILE A 397 
AA9 2 3 N ILE A 398 ? N ILE A 398 O PHE A 421 ? O PHE A 421 
AA9 3 4 N ASP A 422 ? N ASP A 422 O LYS A 427 ? O LYS A 427 
AB1 1 2 N GLU A 405 ? N GLU A 405 O LYS A 413 ? O LYS A 413 
AB2 1 2 N HIS A 446 ? N HIS A 446 O LEU A 449 ? O LEU A 449 
AB2 2 3 N VAL A 450 ? N VAL A 450 O TYR A 462 ? O TYR A 462 
AB3 1 2 N LYS A 486 ? N LYS A 486 O PHE A 497 ? O PHE A 497 
AB3 2 3 N ILE A 494 ? N ILE A 494 O LEU A 511 ? O LEU A 511 
AB3 3 4 N LYS A 510 ? N LYS A 510 O THR A 519 ? O THR A 519 
AB4 1 2 O PHE B 72  ? O PHE B 72  N ILE B 65  ? N ILE B 65  
AB4 2 3 N SER B 66  ? N SER B 66  O ILE B 102 ? O ILE B 102 
AB5 1 2 O VAL B 271 ? O VAL B 271 N LEU B 258 ? N LEU B 258 
AB5 2 3 N ILE B 259 ? N ILE B 259 O PHE B 533 ? O PHE B 533 
AB6 1 2 N HIS B 299 ? N HIS B 299 O ASP B 302 ? O ASP B 302 
AB6 2 3 N LEU B 303 ? N LEU B 303 O CYS B 319 ? O CYS B 319 
AB7 1 2 N THR B 340 ? N THR B 340 O LEU B 353 ? O LEU B 353 
AB7 2 3 N SER B 352 ? N SER B 352 O ILE B 367 ? O ILE B 367 
AB7 3 4 N TYR B 368 ? N TYR B 368 O THR B 377 ? O THR B 377 
AB8 1 2 N LEU B 394 ? N LEU B 394 O ILE B 397 ? O ILE B 397 
AB8 2 3 N ILE B 398 ? N ILE B 398 O PHE B 421 ? O PHE B 421 
AB9 1 2 N GLU B 405 ? N GLU B 405 O LYS B 413 ? O LYS B 413 
AC1 1 2 N ALA B 488 ? N ALA B 488 O TYR B 495 ? O TYR B 495 
AC1 2 3 N VAL B 496 ? N VAL B 496 O TYR B 509 ? O TYR B 509 
AC2 1 2 O TYR C 226 ? O TYR C 226 N SER C 197 ? N SER C 197 
AC2 2 3 O VAL C 196 ? O VAL C 196 N TYR C 172 ? N TYR C 172 
AC2 3 4 N ILE C 173 ? N ILE C 173 O GLN C 260 ? O GLN C 260 
AC2 4 5 N LEU C 259 ? N LEU C 259 O LEU C 298 ? O LEU C 298 
AC2 5 6 O MET C 297 ? O MET C 297 N ALA C 132 ? N ALA C 132 
AC2 6 7 O ILE C 131 ? O ILE C 131 N CYS C 12  ? N CYS C 12  
AC2 7 8 N TYR C 13  ? N TYR C 13  O TYR C 54  ? O TYR C 54  
AC2 8 9 N ARG C 55  ? N ARG C 55  O MET D 135 ? O MET D 31  
# 
_pdbx_entry_details.entry_id                   8VPQ 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 OH  B TYR 351 ? ? OG1 B THR 423 ? ? 2.10 
2 1 OG  A SER 468 ? ? OH  B TYR 31  ? ? 2.11 
3 1 OE2 A GLU 149 ? ? OH  B TYR 35  ? ? 2.12 
4 1 O   C HIS 28  ? ? NZ  C LYS 31  ? ? 2.14 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1   1 VAL A 33  ? ? -137.60 -44.87  
2   1 SER A 41  ? ? -85.69  39.71   
3   1 CYS A 54  ? ? -109.12 -72.87  
4   1 LEU A 55  ? ? -79.69  32.85   
5   1 GLU A 56  ? ? -135.46 -60.13  
6   1 GLU A 58  ? ? 52.33   71.93   
7   1 ASP A 62  ? ? -107.35 -64.49  
8   1 GLU A 68  ? ? 54.49   -83.55  
9   1 SER A 92  ? ? -118.17 64.03   
10  1 ASP A 106 ? ? -149.79 37.42   
11  1 HIS A 189 ? ? -98.81  54.40   
12  1 THR A 196 ? ? -87.45  -118.61 
13  1 GLU A 197 ? ? -155.91 -28.56  
14  1 HIS A 201 ? ? -84.78  40.23   
15  1 SER A 212 ? ? -94.67  34.34   
16  1 ASN A 220 ? ? 54.26   77.34   
17  1 LYS A 233 ? ? 62.07   -71.64  
18  1 GLU A 235 ? ? -94.14  -61.05  
19  1 ARG A 236 ? ? -73.08  30.30   
20  1 ASN A 253 ? ? -80.91  -134.05 
21  1 ILE A 256 ? ? 57.00   92.25   
22  1 SER A 263 ? ? 64.29   175.37  
23  1 ARG A 265 ? ? 54.43   -116.69 
24  1 HIS A 267 ? ? 53.03   -122.31 
25  1 SER A 268 ? ? -135.24 -151.77 
26  1 ALA A 270 ? ? -158.75 52.06   
27  1 GLU A 277 ? ? -81.70  37.93   
28  1 ASN A 287 ? ? -167.15 67.94   
29  1 LEU A 289 ? ? -61.20  91.72   
30  1 HIS A 291 ? ? -120.88 -84.07  
31  1 MET A 313 ? ? -144.34 12.03   
32  1 LEU A 314 ? ? -147.65 22.60   
33  1 VAL A 324 ? ? 70.77   -40.25  
34  1 LEU A 358 ? ? 53.87   -80.63  
35  1 ASN A 364 ? ? -152.08 58.19   
36  1 THR A 377 ? ? -138.08 -125.92 
37  1 GLU A 378 ? ? -174.62 146.67  
38  1 ASN A 395 ? ? 19.51   58.61   
39  1 ASP A 407 ? ? -127.17 -133.50 
40  1 PHE A 411 ? ? -101.94 -158.79 
41  1 ASP A 422 ? ? -57.00  102.89  
42  1 GLU A 424 ? ? -94.09  -63.24  
43  1 PRO A 432 ? ? -73.88  38.96   
44  1 LYS A 447 ? ? 60.25   -122.30 
45  1 ALA A 454 ? ? -150.11 -123.91 
46  1 ASP A 467 ? ? 57.71   70.63   
47  1 LEU A 472 ? ? -106.63 -168.63 
48  1 CYS A 490 ? ? -75.48  -77.88  
49  1 ASN A 491 ? ? -132.89 -64.28  
50  1 LYS A 503 ? ? 64.74   98.00   
51  1 ASP A 505 ? ? -147.14 -24.18  
52  1 ARG A 522 ? ? -151.15 -144.37 
53  1 LEU A 527 ? ? -99.95  31.01   
54  1 THR A 529 ? ? -83.25  -93.76  
55  1 MET B 27  ? ? -146.49 -28.66  
56  1 VAL B 33  ? ? -123.43 -64.70  
57  1 CYS B 54  ? ? -91.57  -67.78  
58  1 GLU B 56  ? ? -127.49 -60.06  
59  1 ASP B 62  ? ? -149.76 13.22   
60  1 GLU B 68  ? ? 35.72   44.01   
61  1 ALA B 81  ? ? -81.94  37.55   
62  1 GLN B 82  ? ? -159.56 -25.26  
63  1 ASN B 99  ? ? -70.79  -104.37 
64  1 ARG B 100 ? ? -165.82 -79.98  
65  1 GLN B 105 ? ? -106.68 -104.73 
66  1 ASP B 106 ? ? -66.08  70.68   
67  1 HIS B 121 ? ? -90.24  -61.78  
68  1 ARG B 156 ? ? -64.10  -71.81  
69  1 GLN B 159 ? ? -78.68  -161.50 
70  1 ASN B 162 ? ? -93.09  37.13   
71  1 HIS B 189 ? ? -140.01 42.95   
72  1 PRO B 203 ? ? -69.38  -174.91 
73  1 SER B 212 ? ? -74.64  46.56   
74  1 ASP B 213 ? ? -135.85 -34.45  
75  1 ASN B 220 ? ? 17.38   82.32   
76  1 PHE B 231 ? ? -128.39 -78.07  
77  1 ASN B 232 ? ? -106.49 58.05   
78  1 ALA B 238 ? ? -78.60  36.37   
79  1 PHE B 239 ? ? -148.44 -9.18   
80  1 LYS B 248 ? ? -127.67 -169.05 
81  1 ASN B 253 ? ? -117.68 55.38   
82  1 ILE B 256 ? ? -132.16 -42.76  
83  1 TYR B 257 ? ? 57.88   83.00   
84  1 SER B 264 ? ? -86.64  -83.29  
85  1 ARG B 265 ? ? -80.90  -154.22 
86  1 ALA B 276 ? ? -78.17  -124.65 
87  1 SER B 282 ? ? -105.66 -165.03 
88  1 SER B 284 ? ? -80.39  -101.05 
89  1 ASN B 287 ? ? -142.56 -44.77  
90  1 SER B 288 ? ? 63.65   164.71  
91  1 THR B 310 ? ? -76.89  -152.19 
92  1 MET B 313 ? ? -96.58  42.03   
93  1 ALA B 322 ? ? -107.63 42.00   
94  1 THR B 323 ? ? -158.98 -22.19  
95  1 ASP B 325 ? ? -119.16 -165.03 
96  1 GLU B 327 ? ? -58.59  95.01   
97  1 ASP B 335 ? ? -106.78 79.06   
98  1 SER B 343 ? ? -134.00 -117.92 
99  1 VAL B 344 ? ? 63.30   114.71  
100 1 LYS B 347 ? ? -166.21 22.52   
101 1 ASP B 348 ? ? 58.96   88.02   
102 1 THR B 357 ? ? -75.18  -166.14 
103 1 GLN B 359 ? ? -96.82  31.18   
104 1 ASN B 364 ? ? -146.63 41.36   
105 1 THR B 379 ? ? -110.95 -164.30 
106 1 ASN B 395 ? ? 20.96   50.07   
107 1 ASP B 407 ? ? -72.04  -108.60 
108 1 LEU B 408 ? ? -155.02 -36.24  
109 1 ASP B 409 ? ? -86.44  32.36   
110 1 PHE B 411 ? ? -110.61 -161.22 
111 1 THR B 423 ? ? -74.40  32.66   
112 1 ASP B 426 ? ? 57.20   72.84   
113 1 LYS B 447 ? ? 61.08   -70.70  
114 1 ASP B 448 ? ? -153.29 -5.03   
115 1 ALA B 454 ? ? -153.46 -97.43  
116 1 GLU B 455 ? ? -64.27  78.79   
117 1 SER B 458 ? ? -169.36 101.02  
118 1 LEU B 472 ? ? -158.88 -32.23  
119 1 CYS B 473 ? ? 67.45   148.26  
120 1 ASN B 491 ? ? 50.88   -85.74  
121 1 ASP B 499 ? ? -61.00  -76.65  
122 1 ARG B 500 ? ? -56.79  91.61   
123 1 TYR B 501 ? ? -64.97  80.31   
124 1 LYS B 503 ? ? 63.52   -51.65  
125 1 ASN B 507 ? ? 25.42   30.18   
126 1 THR B 508 ? ? -172.24 128.72  
127 1 LYS B 510 ? ? -162.22 99.75   
128 1 LYS B 525 ? ? 60.81   -86.32  
129 1 LEU B 528 ? ? -99.74  -148.50 
130 1 THR B 529 ? ? -159.87 -15.87  
131 1 ASN B 530 ? ? -150.99 87.97   
132 1 TYR C 15  ? ? -160.44 116.22  
133 1 ASP C 18  ? ? -166.15 -0.37   
134 1 TYR C 24  ? ? -59.03  -71.68  
135 1 MET C 51  ? ? -162.51 117.51  
136 1 TYR C 67  ? ? -129.52 -60.45  
137 1 SER C 78  ? ? -116.35 59.98   
138 1 ASN C 83  ? ? -107.86 42.78   
139 1 SER C 88  ? ? -104.70 -67.07  
140 1 ASN C 95  ? ? 68.78   -18.70  
141 1 LEU C 106 ? ? 59.85   -79.67  
142 1 GLN C 128 ? ? -88.64  -72.44  
143 1 ASN C 134 ? ? -161.36 102.81  
144 1 PHE C 150 ? ? 69.72   -4.08   
145 1 ILE C 214 ? ? -111.65 -90.09  
146 1 TYR C 222 ? ? -110.30 52.83   
147 1 ALA C 223 ? ? -165.50 102.72  
148 1 GLN C 253 ? ? 55.06   76.29   
149 1 LEU C 266 ? ? -78.21  -161.56 
150 1 CYS C 273 ? ? -164.38 -19.05  
151 1 ASN C 275 ? ? -150.33 37.87   
152 1 PRO C 294 ? ? -55.80  108.69  
153 1 LEU C 320 ? ? -65.64  -97.18  
154 1 ASP C 321 ? ? -177.07 -20.30  
155 1 ASN C 331 ? ? -109.18 -137.83 
156 1 TYR C 333 ? ? -143.09 37.18   
157 1 PRO C 339 ? ? -68.76  59.80   
158 1 ASP C 340 ? ? -155.18 -29.38  
159 1 SER C 348 ? ? -100.78 -142.49 
160 1 ASN C 356 ? ? 54.17   -73.32  
161 1 HIS C 375 ? ? -57.12  104.80  
162 1 ALA D 20  ? ? -157.26 -50.94  
163 1 ASN D 59  ? ? -115.87 -142.28 
164 1 GLU D 61  ? ? -136.81 -50.35  
165 1 ASN D 83  ? ? -66.85  -80.25  
166 1 PHE D 87  ? ? -39.98  101.69  
167 1 ASP D 89  ? ? -66.95  71.10   
168 1 THR D 92  ? ? -72.80  -163.77 
169 1 HIS D 106 ? ? -139.23 -71.78  
170 1 SER D 121 ? ? -78.33  -125.85 
171 1 ILE D 122 ? ? -130.08 -34.73  
172 1 LYS D 133 ? ? -64.70  1.58    
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8VPQ 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    8VPQ 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.3 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               825583 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.5 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 LHC-K4TTYML 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       '1, 2, 3' 
# 
_em_imaging.entry_id                        8VPQ 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'TFS KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             800 
_em_imaging.nominal_defocus_max             1800 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              8VPQ 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                8VPQ 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A MET 1    ? A MET 1   
2   1 Y 1 A LYS 2    ? A LYS 2   
3   1 Y 1 A GLY 3    ? A GLY 3   
4   1 Y 1 A GLY 4    ? A GLY 4   
5   1 Y 1 A ASN 5    ? A ASN 5   
6   1 Y 1 A ALA 6    ? A ALA 6   
7   1 Y 1 A ASP 7    ? A ASP 7   
8   1 Y 1 A SER 8    ? A SER 8   
9   1 Y 1 A TRP 9    ? A TRP 9   
10  1 Y 1 A GLN 10   ? A GLN 10  
11  1 Y 1 A ARG 11   ? A ARG 11  
12  1 Y 1 A GLU 12   ? A GLU 12  
13  1 Y 1 A LYS 13   ? A LYS 13  
14  1 Y 1 A LEU 14   ? A LEU 14  
15  1 Y 1 A ALA 15   ? A ALA 15  
16  1 Y 1 A SER 16   ? A SER 16  
17  1 Y 1 A MET 17   ? A MET 17  
18  1 Y 1 A GLU 18   ? A GLU 18  
19  1 Y 1 A SER 19   ? A SER 19  
20  1 Y 1 A PRO 20   ? A PRO 20  
21  1 Y 1 A GLU 21   ? A GLU 21  
22  1 Y 1 A GLU 22   ? A GLU 22  
23  1 Y 1 A LEU 94   ? A LEU 94  
24  1 Y 1 A LYS 95   ? A LYS 95  
25  1 Y 1 A GLU 96   ? A GLU 96  
26  1 Y 1 A ALA 97   ? A ALA 97  
27  1 Y 1 A HIS 98   ? A HIS 98  
28  1 Y 1 A GLY 308  ? A GLY 308 
29  1 Y 1 A SER 309  ? A SER 309 
30  1 Y 1 A THR 310  ? A THR 310 
31  1 Y 1 A THR 311  ? A THR 311 
32  1 Y 1 A ALA 477  ? A ALA 477 
33  1 Y 1 A TRP 478  ? A TRP 478 
34  1 Y 1 A SER 479  ? A SER 479 
35  1 Y 1 A SER 480  ? A SER 480 
36  1 Y 1 A ALA 481  ? A ALA 481 
37  1 Y 1 A PRO 482  ? A PRO 482 
38  1 Y 1 B MET 1    ? B MET 1   
39  1 Y 1 B LYS 2    ? B LYS 2   
40  1 Y 1 B GLY 3    ? B GLY 3   
41  1 Y 1 B GLY 4    ? B GLY 4   
42  1 Y 1 B ASN 5    ? B ASN 5   
43  1 Y 1 B ALA 6    ? B ALA 6   
44  1 Y 1 B ASP 7    ? B ASP 7   
45  1 Y 1 B SER 8    ? B SER 8   
46  1 Y 1 B TRP 9    ? B TRP 9   
47  1 Y 1 B GLN 10   ? B GLN 10  
48  1 Y 1 B ARG 11   ? B ARG 11  
49  1 Y 1 B GLU 12   ? B GLU 12  
50  1 Y 1 B LYS 13   ? B LYS 13  
51  1 Y 1 B LEU 14   ? B LEU 14  
52  1 Y 1 B ALA 15   ? B ALA 15  
53  1 Y 1 B SER 16   ? B SER 16  
54  1 Y 1 B MET 17   ? B MET 17  
55  1 Y 1 B GLU 18   ? B GLU 18  
56  1 Y 1 B SER 19   ? B SER 19  
57  1 Y 1 B PRO 20   ? B PRO 20  
58  1 Y 1 B GLU 21   ? B GLU 21  
59  1 Y 1 B GLU 22   ? B GLU 22  
60  1 Y 1 B PRO 23   ? B PRO 23  
61  1 Y 1 B GLY 24   ? B GLY 24  
62  1 Y 1 B ALA 25   ? B ALA 25  
63  1 Y 1 B TRP 478  ? B TRP 478 
64  1 Y 1 B SER 479  ? B SER 479 
65  1 Y 1 B SER 480  ? B SER 480 
66  1 Y 1 B ALA 481  ? B ALA 481 
67  1 Y 1 B PRO 482  ? B PRO 482 
68  1 Y 1 C MET 1    ? C MET 1   
69  1 Y 1 C ALA 2    ? C ALA 2   
70  1 Y 1 C GLN 3    ? C GLN 3   
71  1 Y 1 C THR 4    ? C THR 4   
72  1 Y 1 C GLN 5    ? C GLN 5   
73  1 Y 1 C GLY 6    ? C GLY 6   
74  1 Y 1 C THR 7    ? C THR 7   
75  1 Y 1 C PRO 377  ? C PRO 377 
76  1 Y 1 C GLY 378  ? C GLY 378 
77  1 Y 1 C VAL 379  ? C VAL 379 
78  1 Y 1 C GLN 380  ? C GLN 380 
79  1 Y 1 C MET 381  ? C MET 381 
80  1 Y 1 C GLN 382  ? C GLN 382 
81  1 Y 1 C ALA 383  ? C ALA 383 
82  1 Y 1 C ILE 384  ? C ILE 384 
83  1 Y 1 C PRO 385  ? C PRO 385 
84  1 Y 1 C GLU 386  ? C GLU 386 
85  1 Y 1 C ASP 387  ? C ASP 387 
86  1 Y 1 C ALA 388  ? C ALA 388 
87  1 Y 1 C ILE 389  ? C ILE 389 
88  1 Y 1 C PRO 390  ? C PRO 390 
89  1 Y 1 C GLU 391  ? C GLU 391 
90  1 Y 1 C GLU 392  ? C GLU 392 
91  1 Y 1 C SER 393  ? C SER 393 
92  1 Y 1 C GLY 394  ? C GLY 394 
93  1 Y 1 C ASP 395  ? C ASP 395 
94  1 Y 1 C GLU 396  ? C GLU 396 
95  1 Y 1 C ASP 397  ? C ASP 397 
96  1 Y 1 C GLU 398  ? C GLU 398 
97  1 Y 1 C ASP 399  ? C ASP 399 
98  1 Y 1 C ASP 400  ? C ASP 400 
99  1 Y 1 C PRO 401  ? C PRO 401 
100 1 Y 1 C ASP 402  ? C ASP 402 
101 1 Y 1 C LYS 403  ? C LYS 403 
102 1 Y 1 C ARG 404  ? C ARG 404 
103 1 Y 1 C ILE 405  ? C ILE 405 
104 1 Y 1 C SER 406  ? C SER 406 
105 1 Y 1 C ILE 407  ? C ILE 407 
106 1 Y 1 C CYS 408  ? C CYS 408 
107 1 Y 1 C SER 409  ? C SER 409 
108 1 Y 1 C SER 410  ? C SER 410 
109 1 Y 1 C ASP 411  ? C ASP 411 
110 1 Y 1 C LYS 412  ? C LYS 412 
111 1 Y 1 C ARG 413  ? C ARG 413 
112 1 Y 1 C ILE 414  ? C ILE 414 
113 1 Y 1 C ALA 415  ? C ALA 415 
114 1 Y 1 C CYS 416  ? C CYS 416 
115 1 Y 1 C GLU 417  ? C GLU 417 
116 1 Y 1 C GLU 418  ? C GLU 418 
117 1 Y 1 C GLU 419  ? C GLU 419 
118 1 Y 1 C PHE 420  ? C PHE 420 
119 1 Y 1 C SER 421  ? C SER 421 
120 1 Y 1 C ASP 422  ? C ASP 422 
121 1 Y 1 C SER 423  ? C SER 423 
122 1 Y 1 C GLU 424  ? C GLU 424 
123 1 Y 1 C GLU 425  ? C GLU 425 
124 1 Y 1 C GLU 426  ? C GLU 426 
125 1 Y 1 C GLY 427  ? C GLY 427 
126 1 Y 1 C GLU 428  ? C GLU 428 
127 1 Y 1 C GLY 429  ? C GLY 429 
128 1 Y 1 C GLY 430  ? C GLY 430 
129 1 Y 1 C ARG 431  ? C ARG 431 
130 1 Y 1 C LYS 432  ? C LYS 432 
131 1 Y 1 C ASN 433  ? C ASN 433 
132 1 Y 1 C SER 434  ? C SER 434 
133 1 Y 1 C SER 435  ? C SER 435 
134 1 Y 1 C ASN 436  ? C ASN 436 
135 1 Y 1 C PHE 437  ? C PHE 437 
136 1 Y 1 C LYS 438  ? C LYS 438 
137 1 Y 1 C LYS 439  ? C LYS 439 
138 1 Y 1 C ALA 440  ? C ALA 440 
139 1 Y 1 C LYS 441  ? C LYS 441 
140 1 Y 1 C ARG 442  ? C ARG 442 
141 1 Y 1 C VAL 443  ? C VAL 443 
142 1 Y 1 C LYS 444  ? C LYS 444 
143 1 Y 1 C THR 445  ? C THR 445 
144 1 Y 1 C GLU 446  ? C GLU 446 
145 1 Y 1 C ASP 447  ? C ASP 447 
146 1 Y 1 C GLU 448  ? C GLU 448 
147 1 Y 1 C LYS 449  ? C LYS 449 
148 1 Y 1 C GLU 450  ? C GLU 450 
149 1 Y 1 C LYS 451  ? C LYS 451 
150 1 Y 1 C ASP 452  ? C ASP 452 
151 1 Y 1 C PRO 453  ? C PRO 453 
152 1 Y 1 C GLU 454  ? C GLU 454 
153 1 Y 1 C GLU 455  ? C GLU 455 
154 1 Y 1 C LYS 456  ? C LYS 456 
155 1 Y 1 C LYS 457  ? C LYS 457 
156 1 Y 1 C GLU 458  ? C GLU 458 
157 1 Y 1 C VAL 459  ? C VAL 459 
158 1 Y 1 C THR 460  ? C THR 460 
159 1 Y 1 C GLU 461  ? C GLU 461 
160 1 Y 1 C GLU 462  ? C GLU 462 
161 1 Y 1 C GLU 463  ? C GLU 463 
162 1 Y 1 C LYS 464  ? C LYS 464 
163 1 Y 1 C THR 465  ? C THR 465 
164 1 Y 1 C LYS 466  ? C LYS 466 
165 1 Y 1 C GLU 467  ? C GLU 467 
166 1 Y 1 C GLU 468  ? C GLU 468 
167 1 Y 1 C LYS 469  ? C LYS 469 
168 1 Y 1 C PRO 470  ? C PRO 470 
169 1 Y 1 C GLU 471  ? C GLU 471 
170 1 Y 1 C ALA 472  ? C ALA 472 
171 1 Y 1 C LYS 473  ? C LYS 473 
172 1 Y 1 C GLY 474  ? C GLY 474 
173 1 Y 1 C VAL 475  ? C VAL 475 
174 1 Y 1 C LYS 476  ? C LYS 476 
175 1 Y 1 C GLU 477  ? C GLU 477 
176 1 Y 1 C GLU 478  ? C GLU 478 
177 1 Y 1 C VAL 479  ? C VAL 479 
178 1 Y 1 C LYS 480  ? C LYS 480 
179 1 Y 1 C LEU 481  ? C LEU 481 
180 1 Y 1 C ALA 482  ? C ALA 482 
181 1 Y 1 D MET -103 ? D MET 1   
182 1 Y 1 D PRO -102 ? D PRO 2   
183 1 Y 1 D ALA -101 ? D ALA 3   
184 1 Y 1 D MET -100 ? D MET 4   
185 1 Y 1 D VAL -99  ? D VAL 5   
186 1 Y 1 D GLU -98  ? D GLU 6   
187 1 Y 1 D LYS -97  ? D LYS 7   
188 1 Y 1 D GLY -96  ? D GLY 8   
189 1 Y 1 D PRO -95  ? D PRO 9   
190 1 Y 1 D GLU -94  ? D GLU 10  
191 1 Y 1 D VAL -93  ? D VAL 11  
192 1 Y 1 D SER -92  ? D SER 12  
193 1 Y 1 D GLY -91  ? D GLY 13  
194 1 Y 1 D LYS -90  ? D LYS 14  
195 1 Y 1 D ARG -89  ? D ARG 15  
196 1 Y 1 D ARG -88  ? D ARG 16  
197 1 Y 1 D GLY -87  ? D GLY 17  
198 1 Y 1 D ARG -86  ? D ARG 18  
199 1 Y 1 D ASN -85  ? D ASN 19  
200 1 Y 1 D ASN -84  ? D ASN 20  
201 1 Y 1 D ALA -83  ? D ALA 21  
202 1 Y 1 D ALA -82  ? D ALA 22  
203 1 Y 1 D ALA -81  ? D ALA 23  
204 1 Y 1 D SER -80  ? D SER 24  
205 1 Y 1 D ALA -79  ? D ALA 25  
206 1 Y 1 D SER -78  ? D SER 26  
207 1 Y 1 D ALA -77  ? D ALA 27  
208 1 Y 1 D ALA -76  ? D ALA 28  
209 1 Y 1 D ALA -75  ? D ALA 29  
210 1 Y 1 D ALA -74  ? D ALA 30  
211 1 Y 1 D SER -73  ? D SER 31  
212 1 Y 1 D ALA -72  ? D ALA 32  
213 1 Y 1 D ALA -71  ? D ALA 33  
214 1 Y 1 D ALA -70  ? D ALA 34  
215 1 Y 1 D SER -69  ? D SER 35  
216 1 Y 1 D ALA -68  ? D ALA 36  
217 1 Y 1 D ALA -67  ? D ALA 37  
218 1 Y 1 D CYS -66  ? D CYS 38  
219 1 Y 1 D ALA -65  ? D ALA 39  
220 1 Y 1 D SER -64  ? D SER 40  
221 1 Y 1 D PRO -63  ? D PRO 41  
222 1 Y 1 D ALA -62  ? D ALA 42  
223 1 Y 1 D ALA -61  ? D ALA 43  
224 1 Y 1 D THR -60  ? D THR 44  
225 1 Y 1 D ALA -59  ? D ALA 45  
226 1 Y 1 D ALA -58  ? D ALA 46  
227 1 Y 1 D SER -57  ? D SER 47  
228 1 Y 1 D GLY -56  ? D GLY 48  
229 1 Y 1 D ALA -55  ? D ALA 49  
230 1 Y 1 D ALA -54  ? D ALA 50  
231 1 Y 1 D ALA -53  ? D ALA 51  
232 1 Y 1 D SER -52  ? D SER 52  
233 1 Y 1 D SER -51  ? D SER 53  
234 1 Y 1 D ALA -50  ? D ALA 54  
235 1 Y 1 D SER -49  ? D SER 55  
236 1 Y 1 D ALA -48  ? D ALA 56  
237 1 Y 1 D ALA -47  ? D ALA 57  
238 1 Y 1 D ALA -46  ? D ALA 58  
239 1 Y 1 D ALA -45  ? D ALA 59  
240 1 Y 1 D SER -44  ? D SER 60  
241 1 Y 1 D ALA -43  ? D ALA 61  
242 1 Y 1 D ALA -42  ? D ALA 62  
243 1 Y 1 D ALA -41  ? D ALA 63  
244 1 Y 1 D ALA -40  ? D ALA 64  
245 1 Y 1 D PRO -39  ? D PRO 65  
246 1 Y 1 D ASN -38  ? D ASN 66  
247 1 Y 1 D ASN -37  ? D ASN 67  
248 1 Y 1 D GLY -36  ? D GLY 68  
249 1 Y 1 D GLN -35  ? D GLN 69  
250 1 Y 1 D ASN -34  ? D ASN 70  
251 1 Y 1 D LYS -33  ? D LYS 71  
252 1 Y 1 D SER -32  ? D SER 72  
253 1 Y 1 D LEU -31  ? D LEU 73  
254 1 Y 1 D ALA -30  ? D ALA 74  
255 1 Y 1 D ALA -29  ? D ALA 75  
256 1 Y 1 D ALA -28  ? D ALA 76  
257 1 Y 1 D ALA -27  ? D ALA 77  
258 1 Y 1 D PRO -26  ? D PRO 78  
259 1 Y 1 D ASN -25  ? D ASN 79  
260 1 Y 1 D GLY -24  ? D GLY 80  
261 1 Y 1 D ASN -23  ? D ASN 81  
262 1 Y 1 D SER -22  ? D SER 82  
263 1 Y 1 D SER -21  ? D SER 83  
264 1 Y 1 D SER -20  ? D SER 84  
265 1 Y 1 D ASN -19  ? D ASN 85  
266 1 Y 1 D SER -18  ? D SER 86  
267 1 Y 1 D TRP -17  ? D TRP 87  
268 1 Y 1 D GLU -16  ? D GLU 88  
269 1 Y 1 D GLU -15  ? D GLU 89  
270 1 Y 1 D GLY -14  ? D GLY 90  
271 1 Y 1 D SER -13  ? D SER 91  
272 1 Y 1 D SER -12  ? D SER 92  
273 1 Y 1 D GLY -11  ? D GLY 93  
274 1 Y 1 D SER -10  ? D SER 94  
275 1 Y 1 D SER -9   ? D SER 95  
276 1 Y 1 D SER -8   ? D SER 96  
277 1 Y 1 D ASP -7   ? D ASP 97  
278 1 Y 1 D GLU -6   ? D GLU 98  
279 1 Y 1 D GLU -5   ? D GLU 99  
280 1 Y 1 D HIS -4   ? D HIS 100 
281 1 Y 1 D GLY -3   ? D GLY 101 
282 1 Y 1 D GLY -2   ? D GLY 102 
283 1 Y 1 D GLY -1   ? D GLY 103 
284 1 Y 1 D GLY 0    ? D GLY 104 
285 1 Y 1 D ARG 136  ? D ARG 240 
286 1 Y 1 D THR 137  ? D THR 241 
287 1 Y 1 D LYS 138  ? D LYS 242 
288 1 Y 1 D THR 139  ? D THR 243 
289 1 Y 1 D SER 140  ? D SER 244 
290 1 Y 1 D VAL 141  ? D VAL 245 
291 1 Y 1 D MET 142  ? D MET 246 
292 1 Y 1 D ASP 143  ? D ASP 247 
293 1 Y 1 D ARG 144  ? D ARG 248 
294 1 Y 1 D HIS 145  ? D HIS 249 
295 1 Y 1 D ALA 146  ? D ALA 250 
296 1 Y 1 D ARG 147  ? D ARG 251 
297 1 Y 1 D LYS 148  ? D LYS 252 
298 1 Y 1 D GLN 149  ? D GLN 253 
299 1 Y 1 D LYS 150  ? D LYS 254 
300 1 Y 1 D ARG 151  ? D ARG 255 
301 1 Y 1 D GLU 152  ? D GLU 256 
302 1 Y 1 D ARG 153  ? D ARG 257 
303 1 Y 1 D GLU 154  ? D GLU 258 
304 1 Y 1 D GLU 155  ? D GLU 259 
305 1 Y 1 D SER 156  ? D SER 260 
306 1 Y 1 D GLU 157  ? D GLU 261 
307 1 Y 1 D ASP 158  ? D ASP 262 
308 1 Y 1 D GLU 159  ? D GLU 263 
309 1 Y 1 D LEU 160  ? D LEU 264 
310 1 Y 1 D GLU 161  ? D GLU 265 
311 1 Y 1 D GLU 162  ? D GLU 266 
312 1 Y 1 D ALA 163  ? D ALA 267 
313 1 Y 1 D ASN 164  ? D ASN 268 
314 1 Y 1 D GLY 165  ? D GLY 269 
315 1 Y 1 D ASN 166  ? D ASN 270 
316 1 Y 1 D ASN 167  ? D ASN 271 
317 1 Y 1 D PRO 168  ? D PRO 272 
318 1 Y 1 D ILE 169  ? D ILE 273 
319 1 Y 1 D ASP 170  ? D ASP 274 
320 1 Y 1 D ILE 171  ? D ILE 275 
321 1 Y 1 D GLU 172  ? D GLU 276 
322 1 Y 1 D VAL 173  ? D VAL 277 
323 1 Y 1 D ASP 174  ? D ASP 278 
324 1 Y 1 D GLN 175  ? D GLN 279 
325 1 Y 1 D ASN 176  ? D ASN 280 
326 1 Y 1 D LYS 177  ? D LYS 281 
327 1 Y 1 D GLU 178  ? D GLU 282 
328 1 Y 1 D SER 179  ? D SER 283 
329 1 Y 1 D LYS 180  ? D LYS 284 
330 1 Y 1 D LYS 181  ? D LYS 285 
331 1 Y 1 D GLU 182  ? D GLU 286 
332 1 Y 1 D VAL 183  ? D VAL 287 
333 1 Y 1 D PRO 184  ? D PRO 288 
334 1 Y 1 D PRO 185  ? D PRO 289 
335 1 Y 1 D THR 186  ? D THR 290 
336 1 Y 1 D GLU 187  ? D GLU 291 
337 1 Y 1 D THR 188  ? D THR 292 
338 1 Y 1 D VAL 189  ? D VAL 293 
339 1 Y 1 D PRO 190  ? D PRO 294 
340 1 Y 1 D GLN 191  ? D GLN 295 
341 1 Y 1 D VAL 192  ? D VAL 296 
342 1 Y 1 D LYS 193  ? D LYS 297 
343 1 Y 1 D LYS 194  ? D LYS 298 
344 1 Y 1 D GLU 195  ? D GLU 299 
345 1 Y 1 D LYS 196  ? D LYS 300 
346 1 Y 1 D HIS 197  ? D HIS 301 
347 1 Y 1 D SER 198  ? D SER 302 
348 1 Y 1 D THR 199  ? D THR 303 
349 1 Y 1 D GLN 200  ? D GLN 304 
350 1 Y 1 D ALA 201  ? D ALA 305 
351 1 Y 1 D LYS 202  ? D LYS 306 
352 1 Y 1 D ASN 203  ? D ASN 307 
353 1 Y 1 D ARG 204  ? D ARG 308 
354 1 Y 1 D ALA 205  ? D ALA 309 
355 1 Y 1 D LYS 206  ? D LYS 310 
356 1 Y 1 D ARG 207  ? D ARG 311 
357 1 Y 1 D LYS 208  ? D LYS 312 
358 1 Y 1 D PRO 209  ? D PRO 313 
359 1 Y 1 D PRO 210  ? D PRO 314 
360 1 Y 1 D LYS 211  ? D LYS 315 
361 1 Y 1 D GLY 212  ? D GLY 316 
362 1 Y 1 D MET 213  ? D MET 317 
363 1 Y 1 D PHE 214  ? D PHE 318 
364 1 Y 1 D LEU 215  ? D LEU 319 
365 1 Y 1 D SER 216  ? D SER 320 
366 1 Y 1 D GLN 217  ? D GLN 321 
367 1 Y 1 D GLU 218  ? D GLU 322 
368 1 Y 1 D ASP 219  ? D ASP 323 
369 1 Y 1 D VAL 220  ? D VAL 324 
370 1 Y 1 D GLU 221  ? D GLU 325 
371 1 Y 1 D ALA 222  ? D ALA 326 
372 1 Y 1 D VAL 223  ? D VAL 327 
373 1 Y 1 D SER 224  ? D SER 328 
374 1 Y 1 D ALA 225  ? D ALA 329 
375 1 Y 1 D ASN 226  ? D ASN 330 
376 1 Y 1 D ALA 227  ? D ALA 331 
377 1 Y 1 D THR 228  ? D THR 332 
378 1 Y 1 D ALA 229  ? D ALA 333 
379 1 Y 1 D ALA 230  ? D ALA 334 
380 1 Y 1 D THR 231  ? D THR 335 
381 1 Y 1 D THR 232  ? D THR 336 
382 1 Y 1 D VAL 233  ? D VAL 337 
383 1 Y 1 D LEU 234  ? D LEU 338 
384 1 Y 1 D ARG 235  ? D ARG 339 
385 1 Y 1 D GLN 236  ? D GLN 340 
386 1 Y 1 D LEU 237  ? D LEU 341 
387 1 Y 1 D ASP 238  ? D ASP 342 
388 1 Y 1 D MET 239  ? D MET 343 
389 1 Y 1 D GLU 240  ? D GLU 344 
390 1 Y 1 D LEU 241  ? D LEU 345 
391 1 Y 1 D VAL 242  ? D VAL 346 
392 1 Y 1 D SER 243  ? D SER 347 
393 1 Y 1 D VAL 244  ? D VAL 348 
394 1 Y 1 D LYS 245  ? D LYS 349 
395 1 Y 1 D ARG 246  ? D ARG 350 
396 1 Y 1 D GLN 247  ? D GLN 351 
397 1 Y 1 D ILE 248  ? D ILE 352 
398 1 Y 1 D GLN 249  ? D GLN 353 
399 1 Y 1 D ASN 250  ? D ASN 354 
400 1 Y 1 D ILE 251  ? D ILE 355 
401 1 Y 1 D LYS 252  ? D LYS 356 
402 1 Y 1 D GLN 253  ? D GLN 357 
403 1 Y 1 D THR 254  ? D THR 358 
404 1 Y 1 D ASN 255  ? D ASN 359 
405 1 Y 1 D SER 256  ? D SER 360 
406 1 Y 1 D ALA 257  ? D ALA 361 
407 1 Y 1 D LEU 258  ? D LEU 362 
408 1 Y 1 D LYS 259  ? D LYS 363 
409 1 Y 1 D GLU 260  ? D GLU 364 
410 1 Y 1 D LYS 261  ? D LYS 365 
411 1 Y 1 D LEU 262  ? D LEU 366 
412 1 Y 1 D ASP 263  ? D ASP 367 
413 1 Y 1 D GLY 264  ? D GLY 368 
414 1 Y 1 D GLY 265  ? D GLY 369 
415 1 Y 1 D ILE 266  ? D ILE 370 
416 1 Y 1 D GLU 267  ? D GLU 371 
417 1 Y 1 D PRO 268  ? D PRO 372 
418 1 Y 1 D TYR 269  ? D TYR 373 
419 1 Y 1 D ARG 270  ? D ARG 374 
420 1 Y 1 D LEU 271  ? D LEU 375 
421 1 Y 1 D PRO 272  ? D PRO 376 
422 1 Y 1 D GLU 273  ? D GLU 377 
423 1 Y 1 D VAL 274  ? D VAL 378 
424 1 Y 1 D ILE 275  ? D ILE 379 
425 1 Y 1 D GLN 276  ? D GLN 380 
426 1 Y 1 D LYS 277  ? D LYS 381 
427 1 Y 1 D CYS 278  ? D CYS 382 
428 1 Y 1 D ASN 279  ? D ASN 383 
429 1 Y 1 D ALA 280  ? D ALA 384 
430 1 Y 1 D ARG 281  ? D ARG 385 
431 1 Y 1 D TRP 282  ? D TRP 386 
432 1 Y 1 D THR 283  ? D THR 387 
433 1 Y 1 D THR 284  ? D THR 388 
434 1 Y 1 D GLU 285  ? D GLU 389 
435 1 Y 1 D GLU 286  ? D GLU 390 
436 1 Y 1 D GLN 287  ? D GLN 391 
437 1 Y 1 D LEU 288  ? D LEU 392 
438 1 Y 1 D LEU 289  ? D LEU 393 
439 1 Y 1 D ALA 290  ? D ALA 394 
440 1 Y 1 D VAL 291  ? D VAL 395 
441 1 Y 1 D GLN 292  ? D GLN 396 
442 1 Y 1 D ALA 293  ? D ALA 397 
443 1 Y 1 D ILE 294  ? D ILE 398 
444 1 Y 1 D ARG 295  ? D ARG 399 
445 1 Y 1 D LYS 296  ? D LYS 400 
446 1 Y 1 D TYR 297  ? D TYR 401 
447 1 Y 1 D GLY 298  ? D GLY 402 
448 1 Y 1 D ARG 299  ? D ARG 403 
449 1 Y 1 D ASP 300  ? D ASP 404 
450 1 Y 1 D PHE 301  ? D PHE 405 
451 1 Y 1 D GLN 302  ? D GLN 406 
452 1 Y 1 D ALA 303  ? D ALA 407 
453 1 Y 1 D ILE 304  ? D ILE 408 
454 1 Y 1 D SER 305  ? D SER 409 
455 1 Y 1 D ASP 306  ? D ASP 410 
456 1 Y 1 D VAL 307  ? D VAL 411 
457 1 Y 1 D ILE 308  ? D ILE 412 
458 1 Y 1 D GLY 309  ? D GLY 413 
459 1 Y 1 D ASN 310  ? D ASN 414 
460 1 Y 1 D LYS 311  ? D LYS 415 
461 1 Y 1 D SER 312  ? D SER 416 
462 1 Y 1 D VAL 313  ? D VAL 417 
463 1 Y 1 D VAL 314  ? D VAL 418 
464 1 Y 1 D GLN 315  ? D GLN 419 
465 1 Y 1 D VAL 316  ? D VAL 420 
466 1 Y 1 D LYS 317  ? D LYS 421 
467 1 Y 1 D ASN 318  ? D ASN 422 
468 1 Y 1 D PHE 319  ? D PHE 423 
469 1 Y 1 D PHE 320  ? D PHE 424 
470 1 Y 1 D VAL 321  ? D VAL 425 
471 1 Y 1 D ASN 322  ? D ASN 426 
472 1 Y 1 D TYR 323  ? D TYR 427 
473 1 Y 1 D ARG 324  ? D ARG 428 
474 1 Y 1 D ARG 325  ? D ARG 429 
475 1 Y 1 D ARG 326  ? D ARG 430 
476 1 Y 1 D PHE 327  ? D PHE 431 
477 1 Y 1 D ASN 328  ? D ASN 432 
478 1 Y 1 D ILE 329  ? D ILE 433 
479 1 Y 1 D ASP 330  ? D ASP 434 
480 1 Y 1 D GLU 331  ? D GLU 435 
481 1 Y 1 D VAL 332  ? D VAL 436 
482 1 Y 1 D LEU 333  ? D LEU 437 
483 1 Y 1 D GLN 334  ? D GLN 438 
484 1 Y 1 D GLU 335  ? D GLU 439 
485 1 Y 1 D TRP 336  ? D TRP 440 
486 1 Y 1 D GLU 337  ? D GLU 441 
487 1 Y 1 D ALA 338  ? D ALA 442 
488 1 Y 1 D GLU 339  ? D GLU 443 
489 1 Y 1 D HIS 340  ? D HIS 444 
490 1 Y 1 D GLY 341  ? D GLY 445 
491 1 Y 1 D LYS 342  ? D LYS 446 
492 1 Y 1 D GLU 343  ? D GLU 447 
493 1 Y 1 D GLU 344  ? D GLU 448 
494 1 Y 1 D THR 345  ? D THR 449 
495 1 Y 1 D ASN 346  ? D ASN 450 
496 1 Y 1 D GLY 347  ? D GLY 451 
497 1 Y 1 D PRO 348  ? D PRO 452 
498 1 Y 1 D SER 349  ? D SER 453 
499 1 Y 1 D ASN 350  ? D ASN 454 
500 1 Y 1 D GLN 351  ? D GLN 455 
501 1 Y 1 D LYS 352  ? D LYS 456 
502 1 Y 1 D PRO 353  ? D PRO 457 
503 1 Y 1 D VAL 354  ? D VAL 458 
504 1 Y 1 D LYS 355  ? D LYS 459 
505 1 Y 1 D SER 356  ? D SER 460 
506 1 Y 1 D PRO 357  ? D PRO 461 
507 1 Y 1 D ASP 358  ? D ASP 462 
508 1 Y 1 D ASN 359  ? D ASN 463 
509 1 Y 1 D SER 360  ? D SER 464 
510 1 Y 1 D ILE 361  ? D ILE 465 
511 1 Y 1 D LYS 362  ? D LYS 466 
512 1 Y 1 D MET 363  ? D MET 467 
513 1 Y 1 D PRO 364  ? D PRO 468 
514 1 Y 1 D GLU 365  ? D GLU 469 
515 1 Y 1 D GLU 366  ? D GLU 470 
516 1 Y 1 D GLU 367  ? D GLU 471 
517 1 Y 1 D ASP 368  ? D ASP 472 
518 1 Y 1 D GLU 369  ? D GLU 473 
519 1 Y 1 D ALA 370  ? D ALA 474 
520 1 Y 1 D PRO 371  ? D PRO 475 
521 1 Y 1 D VAL 372  ? D VAL 476 
522 1 Y 1 D LEU 373  ? D LEU 477 
523 1 Y 1 D ASP 374  ? D ASP 478 
524 1 Y 1 D VAL 375  ? D VAL 479 
525 1 Y 1 D ARG 376  ? D ARG 480 
526 1 Y 1 D TYR 377  ? D TYR 481 
527 1 Y 1 D ALA 378  ? D ALA 482 
528 1 Y 1 D SER 379  ? D SER 483 
529 1 Y 1 D ALA 380  ? D ALA 484 
530 1 Y 1 D SER 381  ? D SER 485 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N  N N 1   
ALA CA   C  N S 2   
ALA C    C  N N 3   
ALA O    O  N N 4   
ALA CB   C  N N 5   
ALA OXT  O  N N 6   
ALA H    H  N N 7   
ALA H2   H  N N 8   
ALA HA   H  N N 9   
ALA HB1  H  N N 10  
ALA HB2  H  N N 11  
ALA HB3  H  N N 12  
ALA HXT  H  N N 13  
ARG N    N  N N 14  
ARG CA   C  N S 15  
ARG C    C  N N 16  
ARG O    O  N N 17  
ARG CB   C  N N 18  
ARG CG   C  N N 19  
ARG CD   C  N N 20  
ARG NE   N  N N 21  
ARG CZ   C  N N 22  
ARG NH1  N  N N 23  
ARG NH2  N  N N 24  
ARG OXT  O  N N 25  
ARG H    H  N N 26  
ARG H2   H  N N 27  
ARG HA   H  N N 28  
ARG HB2  H  N N 29  
ARG HB3  H  N N 30  
ARG HG2  H  N N 31  
ARG HG3  H  N N 32  
ARG HD2  H  N N 33  
ARG HD3  H  N N 34  
ARG HE   H  N N 35  
ARG HH11 H  N N 36  
ARG HH12 H  N N 37  
ARG HH21 H  N N 38  
ARG HH22 H  N N 39  
ARG HXT  H  N N 40  
ASN N    N  N N 41  
ASN CA   C  N S 42  
ASN C    C  N N 43  
ASN O    O  N N 44  
ASN CB   C  N N 45  
ASN CG   C  N N 46  
ASN OD1  O  N N 47  
ASN ND2  N  N N 48  
ASN OXT  O  N N 49  
ASN H    H  N N 50  
ASN H2   H  N N 51  
ASN HA   H  N N 52  
ASN HB2  H  N N 53  
ASN HB3  H  N N 54  
ASN HD21 H  N N 55  
ASN HD22 H  N N 56  
ASN HXT  H  N N 57  
ASP N    N  N N 58  
ASP CA   C  N S 59  
ASP C    C  N N 60  
ASP O    O  N N 61  
ASP CB   C  N N 62  
ASP CG   C  N N 63  
ASP OD1  O  N N 64  
ASP OD2  O  N N 65  
ASP OXT  O  N N 66  
ASP H    H  N N 67  
ASP H2   H  N N 68  
ASP HA   H  N N 69  
ASP HB2  H  N N 70  
ASP HB3  H  N N 71  
ASP HD2  H  N N 72  
ASP HXT  H  N N 73  
CYS N    N  N N 74  
CYS CA   C  N R 75  
CYS C    C  N N 76  
CYS O    O  N N 77  
CYS CB   C  N N 78  
CYS SG   S  N N 79  
CYS OXT  O  N N 80  
CYS H    H  N N 81  
CYS H2   H  N N 82  
CYS HA   H  N N 83  
CYS HB2  H  N N 84  
CYS HB3  H  N N 85  
CYS HG   H  N N 86  
CYS HXT  H  N N 87  
GLN N    N  N N 88  
GLN CA   C  N S 89  
GLN C    C  N N 90  
GLN O    O  N N 91  
GLN CB   C  N N 92  
GLN CG   C  N N 93  
GLN CD   C  N N 94  
GLN OE1  O  N N 95  
GLN NE2  N  N N 96  
GLN OXT  O  N N 97  
GLN H    H  N N 98  
GLN H2   H  N N 99  
GLN HA   H  N N 100 
GLN HB2  H  N N 101 
GLN HB3  H  N N 102 
GLN HG2  H  N N 103 
GLN HG3  H  N N 104 
GLN HE21 H  N N 105 
GLN HE22 H  N N 106 
GLN HXT  H  N N 107 
GLU N    N  N N 108 
GLU CA   C  N S 109 
GLU C    C  N N 110 
GLU O    O  N N 111 
GLU CB   C  N N 112 
GLU CG   C  N N 113 
GLU CD   C  N N 114 
GLU OE1  O  N N 115 
GLU OE2  O  N N 116 
GLU OXT  O  N N 117 
GLU H    H  N N 118 
GLU H2   H  N N 119 
GLU HA   H  N N 120 
GLU HB2  H  N N 121 
GLU HB3  H  N N 122 
GLU HG2  H  N N 123 
GLU HG3  H  N N 124 
GLU HE2  H  N N 125 
GLU HXT  H  N N 126 
GLY N    N  N N 127 
GLY CA   C  N N 128 
GLY C    C  N N 129 
GLY O    O  N N 130 
GLY OXT  O  N N 131 
GLY H    H  N N 132 
GLY H2   H  N N 133 
GLY HA2  H  N N 134 
GLY HA3  H  N N 135 
GLY HXT  H  N N 136 
HIS N    N  N N 137 
HIS CA   C  N S 138 
HIS C    C  N N 139 
HIS O    O  N N 140 
HIS CB   C  N N 141 
HIS CG   C  Y N 142 
HIS ND1  N  Y N 143 
HIS CD2  C  Y N 144 
HIS CE1  C  Y N 145 
HIS NE2  N  Y N 146 
HIS OXT  O  N N 147 
HIS H    H  N N 148 
HIS H2   H  N N 149 
HIS HA   H  N N 150 
HIS HB2  H  N N 151 
HIS HB3  H  N N 152 
HIS HD1  H  N N 153 
HIS HD2  H  N N 154 
HIS HE1  H  N N 155 
HIS HE2  H  N N 156 
HIS HXT  H  N N 157 
IHP C1   C  N N 158 
IHP C2   C  N N 159 
IHP C3   C  N N 160 
IHP C4   C  N N 161 
IHP C5   C  N N 162 
IHP C6   C  N N 163 
IHP O11  O  N N 164 
IHP P1   P  N N 165 
IHP O21  O  N N 166 
IHP O31  O  N N 167 
IHP O41  O  N N 168 
IHP O12  O  N N 169 
IHP P2   P  N N 170 
IHP O22  O  N N 171 
IHP O32  O  N N 172 
IHP O42  O  N N 173 
IHP O13  O  N N 174 
IHP P3   P  N N 175 
IHP O23  O  N N 176 
IHP O33  O  N N 177 
IHP O43  O  N N 178 
IHP O14  O  N N 179 
IHP P4   P  N N 180 
IHP O24  O  N N 181 
IHP O34  O  N N 182 
IHP O44  O  N N 183 
IHP O15  O  N N 184 
IHP P5   P  N N 185 
IHP O25  O  N N 186 
IHP O35  O  N N 187 
IHP O45  O  N N 188 
IHP O16  O  N N 189 
IHP P6   P  N N 190 
IHP O26  O  N N 191 
IHP O36  O  N N 192 
IHP O46  O  N N 193 
IHP H1   H  N N 194 
IHP H2   H  N N 195 
IHP H3   H  N N 196 
IHP H4   H  N N 197 
IHP H5   H  N N 198 
IHP H6   H  N N 199 
IHP H31  H  N N 200 
IHP H41  H  N N 201 
IHP H32  H  N N 202 
IHP H42  H  N N 203 
IHP H33  H  N N 204 
IHP H43  H  N N 205 
IHP H34  H  N N 206 
IHP H44  H  N N 207 
IHP H35  H  N N 208 
IHP H45  H  N N 209 
IHP H36  H  N N 210 
IHP H46  H  N N 211 
ILE N    N  N N 212 
ILE CA   C  N S 213 
ILE C    C  N N 214 
ILE O    O  N N 215 
ILE CB   C  N S 216 
ILE CG1  C  N N 217 
ILE CG2  C  N N 218 
ILE CD1  C  N N 219 
ILE OXT  O  N N 220 
ILE H    H  N N 221 
ILE H2   H  N N 222 
ILE HA   H  N N 223 
ILE HB   H  N N 224 
ILE HG12 H  N N 225 
ILE HG13 H  N N 226 
ILE HG21 H  N N 227 
ILE HG22 H  N N 228 
ILE HG23 H  N N 229 
ILE HD11 H  N N 230 
ILE HD12 H  N N 231 
ILE HD13 H  N N 232 
ILE HXT  H  N N 233 
LEU N    N  N N 234 
LEU CA   C  N S 235 
LEU C    C  N N 236 
LEU O    O  N N 237 
LEU CB   C  N N 238 
LEU CG   C  N N 239 
LEU CD1  C  N N 240 
LEU CD2  C  N N 241 
LEU OXT  O  N N 242 
LEU H    H  N N 243 
LEU H2   H  N N 244 
LEU HA   H  N N 245 
LEU HB2  H  N N 246 
LEU HB3  H  N N 247 
LEU HG   H  N N 248 
LEU HD11 H  N N 249 
LEU HD12 H  N N 250 
LEU HD13 H  N N 251 
LEU HD21 H  N N 252 
LEU HD22 H  N N 253 
LEU HD23 H  N N 254 
LEU HXT  H  N N 255 
LYS N    N  N N 256 
LYS CA   C  N S 257 
LYS C    C  N N 258 
LYS O    O  N N 259 
LYS CB   C  N N 260 
LYS CG   C  N N 261 
LYS CD   C  N N 262 
LYS CE   C  N N 263 
LYS NZ   N  N N 264 
LYS OXT  O  N N 265 
LYS H    H  N N 266 
LYS H2   H  N N 267 
LYS HA   H  N N 268 
LYS HB2  H  N N 269 
LYS HB3  H  N N 270 
LYS HG2  H  N N 271 
LYS HG3  H  N N 272 
LYS HD2  H  N N 273 
LYS HD3  H  N N 274 
LYS HE2  H  N N 275 
LYS HE3  H  N N 276 
LYS HZ1  H  N N 277 
LYS HZ2  H  N N 278 
LYS HZ3  H  N N 279 
LYS HXT  H  N N 280 
MET N    N  N N 281 
MET CA   C  N S 282 
MET C    C  N N 283 
MET O    O  N N 284 
MET CB   C  N N 285 
MET CG   C  N N 286 
MET SD   S  N N 287 
MET CE   C  N N 288 
MET OXT  O  N N 289 
MET H    H  N N 290 
MET H2   H  N N 291 
MET HA   H  N N 292 
MET HB2  H  N N 293 
MET HB3  H  N N 294 
MET HG2  H  N N 295 
MET HG3  H  N N 296 
MET HE1  H  N N 297 
MET HE2  H  N N 298 
MET HE3  H  N N 299 
MET HXT  H  N N 300 
PHE N    N  N N 301 
PHE CA   C  N S 302 
PHE C    C  N N 303 
PHE O    O  N N 304 
PHE CB   C  N N 305 
PHE CG   C  Y N 306 
PHE CD1  C  Y N 307 
PHE CD2  C  Y N 308 
PHE CE1  C  Y N 309 
PHE CE2  C  Y N 310 
PHE CZ   C  Y N 311 
PHE OXT  O  N N 312 
PHE H    H  N N 313 
PHE H2   H  N N 314 
PHE HA   H  N N 315 
PHE HB2  H  N N 316 
PHE HB3  H  N N 317 
PHE HD1  H  N N 318 
PHE HD2  H  N N 319 
PHE HE1  H  N N 320 
PHE HE2  H  N N 321 
PHE HZ   H  N N 322 
PHE HXT  H  N N 323 
PRO N    N  N N 324 
PRO CA   C  N S 325 
PRO C    C  N N 326 
PRO O    O  N N 327 
PRO CB   C  N N 328 
PRO CG   C  N N 329 
PRO CD   C  N N 330 
PRO OXT  O  N N 331 
PRO H    H  N N 332 
PRO HA   H  N N 333 
PRO HB2  H  N N 334 
PRO HB3  H  N N 335 
PRO HG2  H  N N 336 
PRO HG3  H  N N 337 
PRO HD2  H  N N 338 
PRO HD3  H  N N 339 
PRO HXT  H  N N 340 
SER N    N  N N 341 
SER CA   C  N S 342 
SER C    C  N N 343 
SER O    O  N N 344 
SER CB   C  N N 345 
SER OG   O  N N 346 
SER OXT  O  N N 347 
SER H    H  N N 348 
SER H2   H  N N 349 
SER HA   H  N N 350 
SER HB2  H  N N 351 
SER HB3  H  N N 352 
SER HG   H  N N 353 
SER HXT  H  N N 354 
THR N    N  N N 355 
THR CA   C  N S 356 
THR C    C  N N 357 
THR O    O  N N 358 
THR CB   C  N R 359 
THR OG1  O  N N 360 
THR CG2  C  N N 361 
THR OXT  O  N N 362 
THR H    H  N N 363 
THR H2   H  N N 364 
THR HA   H  N N 365 
THR HB   H  N N 366 
THR HG1  H  N N 367 
THR HG21 H  N N 368 
THR HG22 H  N N 369 
THR HG23 H  N N 370 
THR HXT  H  N N 371 
TRP N    N  N N 372 
TRP CA   C  N S 373 
TRP C    C  N N 374 
TRP O    O  N N 375 
TRP CB   C  N N 376 
TRP CG   C  Y N 377 
TRP CD1  C  Y N 378 
TRP CD2  C  Y N 379 
TRP NE1  N  Y N 380 
TRP CE2  C  Y N 381 
TRP CE3  C  Y N 382 
TRP CZ2  C  Y N 383 
TRP CZ3  C  Y N 384 
TRP CH2  C  Y N 385 
TRP OXT  O  N N 386 
TRP H    H  N N 387 
TRP H2   H  N N 388 
TRP HA   H  N N 389 
TRP HB2  H  N N 390 
TRP HB3  H  N N 391 
TRP HD1  H  N N 392 
TRP HE1  H  N N 393 
TRP HE3  H  N N 394 
TRP HZ2  H  N N 395 
TRP HZ3  H  N N 396 
TRP HH2  H  N N 397 
TRP HXT  H  N N 398 
TYR N    N  N N 399 
TYR CA   C  N S 400 
TYR C    C  N N 401 
TYR O    O  N N 402 
TYR CB   C  N N 403 
TYR CG   C  Y N 404 
TYR CD1  C  Y N 405 
TYR CD2  C  Y N 406 
TYR CE1  C  Y N 407 
TYR CE2  C  Y N 408 
TYR CZ   C  Y N 409 
TYR OH   O  N N 410 
TYR OXT  O  N N 411 
TYR H    H  N N 412 
TYR H2   H  N N 413 
TYR HA   H  N N 414 
TYR HB2  H  N N 415 
TYR HB3  H  N N 416 
TYR HD1  H  N N 417 
TYR HD2  H  N N 418 
TYR HE1  H  N N 419 
TYR HE2  H  N N 420 
TYR HH   H  N N 421 
TYR HXT  H  N N 422 
VAL N    N  N N 423 
VAL CA   C  N S 424 
VAL C    C  N N 425 
VAL O    O  N N 426 
VAL CB   C  N N 427 
VAL CG1  C  N N 428 
VAL CG2  C  N N 429 
VAL OXT  O  N N 430 
VAL H    H  N N 431 
VAL H2   H  N N 432 
VAL HA   H  N N 433 
VAL HB   H  N N 434 
VAL HG11 H  N N 435 
VAL HG12 H  N N 436 
VAL HG13 H  N N 437 
VAL HG21 H  N N 438 
VAL HG22 H  N N 439 
VAL HG23 H  N N 440 
VAL HXT  H  N N 441 
ZN  ZN   ZN N N 442 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
IHP C1  C2   sing N N 150 
IHP C1  C6   sing N N 151 
IHP C1  O11  sing N N 152 
IHP C1  H1   sing N N 153 
IHP C2  C3   sing N N 154 
IHP C2  O12  sing N N 155 
IHP C2  H2   sing N N 156 
IHP C3  C4   sing N N 157 
IHP C3  O13  sing N N 158 
IHP C3  H3   sing N N 159 
IHP C4  C5   sing N N 160 
IHP C4  O14  sing N N 161 
IHP C4  H4   sing N N 162 
IHP C5  C6   sing N N 163 
IHP C5  O15  sing N N 164 
IHP C5  H5   sing N N 165 
IHP C6  O16  sing N N 166 
IHP C6  H6   sing N N 167 
IHP O11 P1   sing N N 168 
IHP P1  O21  doub N N 169 
IHP P1  O31  sing N N 170 
IHP P1  O41  sing N N 171 
IHP O31 H31  sing N N 172 
IHP O41 H41  sing N N 173 
IHP O12 P2   sing N N 174 
IHP P2  O22  doub N N 175 
IHP P2  O32  sing N N 176 
IHP P2  O42  sing N N 177 
IHP O32 H32  sing N N 178 
IHP O42 H42  sing N N 179 
IHP O13 P3   sing N N 180 
IHP P3  O23  doub N N 181 
IHP P3  O33  sing N N 182 
IHP P3  O43  sing N N 183 
IHP O33 H33  sing N N 184 
IHP O43 H43  sing N N 185 
IHP O14 P4   sing N N 186 
IHP P4  O24  doub N N 187 
IHP P4  O34  sing N N 188 
IHP P4  O44  sing N N 189 
IHP O34 H34  sing N N 190 
IHP O44 H44  sing N N 191 
IHP O15 P5   sing N N 192 
IHP P5  O25  doub N N 193 
IHP P5  O35  sing N N 194 
IHP P5  O45  sing N N 195 
IHP O35 H35  sing N N 196 
IHP O45 H45  sing N N 197 
IHP O16 P6   sing N N 198 
IHP P6  O26  doub N N 199 
IHP P6  O36  sing N N 200 
IHP P6  O46  sing N N 201 
IHP O36 H36  sing N N 202 
IHP O46 H46  sing N N 203 
ILE N   CA   sing N N 204 
ILE N   H    sing N N 205 
ILE N   H2   sing N N 206 
ILE CA  C    sing N N 207 
ILE CA  CB   sing N N 208 
ILE CA  HA   sing N N 209 
ILE C   O    doub N N 210 
ILE C   OXT  sing N N 211 
ILE CB  CG1  sing N N 212 
ILE CB  CG2  sing N N 213 
ILE CB  HB   sing N N 214 
ILE CG1 CD1  sing N N 215 
ILE CG1 HG12 sing N N 216 
ILE CG1 HG13 sing N N 217 
ILE CG2 HG21 sing N N 218 
ILE CG2 HG22 sing N N 219 
ILE CG2 HG23 sing N N 220 
ILE CD1 HD11 sing N N 221 
ILE CD1 HD12 sing N N 222 
ILE CD1 HD13 sing N N 223 
ILE OXT HXT  sing N N 224 
LEU N   CA   sing N N 225 
LEU N   H    sing N N 226 
LEU N   H2   sing N N 227 
LEU CA  C    sing N N 228 
LEU CA  CB   sing N N 229 
LEU CA  HA   sing N N 230 
LEU C   O    doub N N 231 
LEU C   OXT  sing N N 232 
LEU CB  CG   sing N N 233 
LEU CB  HB2  sing N N 234 
LEU CB  HB3  sing N N 235 
LEU CG  CD1  sing N N 236 
LEU CG  CD2  sing N N 237 
LEU CG  HG   sing N N 238 
LEU CD1 HD11 sing N N 239 
LEU CD1 HD12 sing N N 240 
LEU CD1 HD13 sing N N 241 
LEU CD2 HD21 sing N N 242 
LEU CD2 HD22 sing N N 243 
LEU CD2 HD23 sing N N 244 
LEU OXT HXT  sing N N 245 
LYS N   CA   sing N N 246 
LYS N   H    sing N N 247 
LYS N   H2   sing N N 248 
LYS CA  C    sing N N 249 
LYS CA  CB   sing N N 250 
LYS CA  HA   sing N N 251 
LYS C   O    doub N N 252 
LYS C   OXT  sing N N 253 
LYS CB  CG   sing N N 254 
LYS CB  HB2  sing N N 255 
LYS CB  HB3  sing N N 256 
LYS CG  CD   sing N N 257 
LYS CG  HG2  sing N N 258 
LYS CG  HG3  sing N N 259 
LYS CD  CE   sing N N 260 
LYS CD  HD2  sing N N 261 
LYS CD  HD3  sing N N 262 
LYS CE  NZ   sing N N 263 
LYS CE  HE2  sing N N 264 
LYS CE  HE3  sing N N 265 
LYS NZ  HZ1  sing N N 266 
LYS NZ  HZ2  sing N N 267 
LYS NZ  HZ3  sing N N 268 
LYS OXT HXT  sing N N 269 
MET N   CA   sing N N 270 
MET N   H    sing N N 271 
MET N   H2   sing N N 272 
MET CA  C    sing N N 273 
MET CA  CB   sing N N 274 
MET CA  HA   sing N N 275 
MET C   O    doub N N 276 
MET C   OXT  sing N N 277 
MET CB  CG   sing N N 278 
MET CB  HB2  sing N N 279 
MET CB  HB3  sing N N 280 
MET CG  SD   sing N N 281 
MET CG  HG2  sing N N 282 
MET CG  HG3  sing N N 283 
MET SD  CE   sing N N 284 
MET CE  HE1  sing N N 285 
MET CE  HE2  sing N N 286 
MET CE  HE3  sing N N 287 
MET OXT HXT  sing N N 288 
PHE N   CA   sing N N 289 
PHE N   H    sing N N 290 
PHE N   H2   sing N N 291 
PHE CA  C    sing N N 292 
PHE CA  CB   sing N N 293 
PHE CA  HA   sing N N 294 
PHE C   O    doub N N 295 
PHE C   OXT  sing N N 296 
PHE CB  CG   sing N N 297 
PHE CB  HB2  sing N N 298 
PHE CB  HB3  sing N N 299 
PHE CG  CD1  doub Y N 300 
PHE CG  CD2  sing Y N 301 
PHE CD1 CE1  sing Y N 302 
PHE CD1 HD1  sing N N 303 
PHE CD2 CE2  doub Y N 304 
PHE CD2 HD2  sing N N 305 
PHE CE1 CZ   doub Y N 306 
PHE CE1 HE1  sing N N 307 
PHE CE2 CZ   sing Y N 308 
PHE CE2 HE2  sing N N 309 
PHE CZ  HZ   sing N N 310 
PHE OXT HXT  sing N N 311 
PRO N   CA   sing N N 312 
PRO N   CD   sing N N 313 
PRO N   H    sing N N 314 
PRO CA  C    sing N N 315 
PRO CA  CB   sing N N 316 
PRO CA  HA   sing N N 317 
PRO C   O    doub N N 318 
PRO C   OXT  sing N N 319 
PRO CB  CG   sing N N 320 
PRO CB  HB2  sing N N 321 
PRO CB  HB3  sing N N 322 
PRO CG  CD   sing N N 323 
PRO CG  HG2  sing N N 324 
PRO CG  HG3  sing N N 325 
PRO CD  HD2  sing N N 326 
PRO CD  HD3  sing N N 327 
PRO OXT HXT  sing N N 328 
SER N   CA   sing N N 329 
SER N   H    sing N N 330 
SER N   H2   sing N N 331 
SER CA  C    sing N N 332 
SER CA  CB   sing N N 333 
SER CA  HA   sing N N 334 
SER C   O    doub N N 335 
SER C   OXT  sing N N 336 
SER CB  OG   sing N N 337 
SER CB  HB2  sing N N 338 
SER CB  HB3  sing N N 339 
SER OG  HG   sing N N 340 
SER OXT HXT  sing N N 341 
THR N   CA   sing N N 342 
THR N   H    sing N N 343 
THR N   H2   sing N N 344 
THR CA  C    sing N N 345 
THR CA  CB   sing N N 346 
THR CA  HA   sing N N 347 
THR C   O    doub N N 348 
THR C   OXT  sing N N 349 
THR CB  OG1  sing N N 350 
THR CB  CG2  sing N N 351 
THR CB  HB   sing N N 352 
THR OG1 HG1  sing N N 353 
THR CG2 HG21 sing N N 354 
THR CG2 HG22 sing N N 355 
THR CG2 HG23 sing N N 356 
THR OXT HXT  sing N N 357 
TRP N   CA   sing N N 358 
TRP N   H    sing N N 359 
TRP N   H2   sing N N 360 
TRP CA  C    sing N N 361 
TRP CA  CB   sing N N 362 
TRP CA  HA   sing N N 363 
TRP C   O    doub N N 364 
TRP C   OXT  sing N N 365 
TRP CB  CG   sing N N 366 
TRP CB  HB2  sing N N 367 
TRP CB  HB3  sing N N 368 
TRP CG  CD1  doub Y N 369 
TRP CG  CD2  sing Y N 370 
TRP CD1 NE1  sing Y N 371 
TRP CD1 HD1  sing N N 372 
TRP CD2 CE2  doub Y N 373 
TRP CD2 CE3  sing Y N 374 
TRP NE1 CE2  sing Y N 375 
TRP NE1 HE1  sing N N 376 
TRP CE2 CZ2  sing Y N 377 
TRP CE3 CZ3  doub Y N 378 
TRP CE3 HE3  sing N N 379 
TRP CZ2 CH2  doub Y N 380 
TRP CZ2 HZ2  sing N N 381 
TRP CZ3 CH2  sing Y N 382 
TRP CZ3 HZ3  sing N N 383 
TRP CH2 HH2  sing N N 384 
TRP OXT HXT  sing N N 385 
TYR N   CA   sing N N 386 
TYR N   H    sing N N 387 
TYR N   H2   sing N N 388 
TYR CA  C    sing N N 389 
TYR CA  CB   sing N N 390 
TYR CA  HA   sing N N 391 
TYR C   O    doub N N 392 
TYR C   OXT  sing N N 393 
TYR CB  CG   sing N N 394 
TYR CB  HB2  sing N N 395 
TYR CB  HB3  sing N N 396 
TYR CG  CD1  doub Y N 397 
TYR CG  CD2  sing Y N 398 
TYR CD1 CE1  sing Y N 399 
TYR CD1 HD1  sing N N 400 
TYR CD2 CE2  doub Y N 401 
TYR CD2 HD2  sing N N 402 
TYR CE1 CZ   doub Y N 403 
TYR CE1 HE1  sing N N 404 
TYR CE2 CZ   sing Y N 405 
TYR CE2 HE2  sing N N 406 
TYR CZ  OH   sing N N 407 
TYR OH  HH   sing N N 408 
TYR OXT HXT  sing N N 409 
VAL N   CA   sing N N 410 
VAL N   H    sing N N 411 
VAL N   H2   sing N N 412 
VAL CA  C    sing N N 413 
VAL CA  CB   sing N N 414 
VAL CA  HA   sing N N 415 
VAL C   O    doub N N 416 
VAL C   OXT  sing N N 417 
VAL CB  CG1  sing N N 418 
VAL CB  CG2  sing N N 419 
VAL CB  HB   sing N N 420 
VAL CG1 HG11 sing N N 421 
VAL CG1 HG12 sing N N 422 
VAL CG1 HG13 sing N N 423 
VAL CG2 HG21 sing N N 424 
VAL CG2 HG22 sing N N 425 
VAL CG2 HG23 sing N N 426 
VAL OXT HXT  sing N N 427 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-01-16 
_em_admin.deposition_site    RCSB 
_em_admin.entry_id           8VPQ 
_em_admin.last_update        2024-12-04 
_em_admin.map_release_date   2024-11-27 
_em_admin.title              'The structure of LSD1-CoREST-HDAC1 in complex with KBTBD4IPR310delinsTTYML' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING ONLY' 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          9606 
_em_entity_assembly_recombinant.organism             'Homo sapiens' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         49 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? ?      ?            
'MODEL REFINEMENT'         ? 2  ? ? ? PHENIX 1.11.1_2575: 
'IMAGE ACQUISITION'        ? 3  ? ? 1 ?      ?            
MASKING                    ? 4  ? ? ? ?      ?            
'CTF CORRECTION'           ? 5  1 ? ? ?      ?            
'LAYERLINE INDEXING'       ? 6  ? ? ? ?      ?            
'DIFFRACTION INDEXING'     ? 7  ? ? ? ?      ?            
'MODEL FITTING'            ? 8  ? ? ? ?      ?            
OTHER                      ? 9  ? ? ? ?      ?            
'INITIAL EULER ASSIGNMENT' ? 10 1 ? ? ?      ?            
'FINAL EULER ASSIGNMENT'   ? 11 1 ? ? ?      ?            
CLASSIFICATION             ? 12 1 ? ? ?      ?            
RECONSTRUCTION             ? 13 1 ? ? ?      ?            
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'Howard Hughes Medical Institute (HHMI)' 
_pdbx_audit_support.country                'United States' 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    8VPQ 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C  
N  
O  
P  
S  
ZN 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1     N  N   . PRO A 1 23  ? 150.451 177.481 161.456 1.00 73.40  ? 23  PRO A N   1 
ATOM   2     C  CA  . PRO A 1 23  ? 149.494 176.371 161.411 1.00 73.40  ? 23  PRO A CA  1 
ATOM   3     C  C   . PRO A 1 23  ? 148.078 176.833 161.081 1.00 73.40  ? 23  PRO A C   1 
ATOM   4     O  O   . PRO A 1 23  ? 147.306 176.081 160.486 1.00 73.40  ? 23  PRO A O   1 
ATOM   5     C  CB  . PRO A 1 23  ? 149.559 175.796 162.829 1.00 73.40  ? 23  PRO A CB  1 
ATOM   6     C  CG  . PRO A 1 23  ? 150.902 176.194 163.336 1.00 73.40  ? 23  PRO A CG  1 
ATOM   7     C  CD  . PRO A 1 23  ? 151.166 177.541 162.742 1.00 73.40  ? 23  PRO A CD  1 
ATOM   8     N  N   . GLY A 1 24  ? 147.747 178.061 161.471 1.00 73.79  ? 24  GLY A N   1 
ATOM   9     C  CA  . GLY A 1 24  ? 146.417 178.588 161.230 1.00 73.79  ? 24  GLY A CA  1 
ATOM   10    C  C   . GLY A 1 24  ? 146.340 179.267 159.878 1.00 73.79  ? 24  GLY A C   1 
ATOM   11    O  O   . GLY A 1 24  ? 147.201 180.099 159.544 1.00 73.79  ? 24  GLY A O   1 
ATOM   12    N  N   . ALA A 1 25  ? 145.321 178.931 159.089 1.00 74.62  ? 25  ALA A N   1 
ATOM   13    C  CA  . ALA A 1 25  ? 145.136 179.492 157.751 1.00 74.62  ? 25  ALA A CA  1 
ATOM   14    C  C   . ALA A 1 25  ? 144.407 180.824 157.893 1.00 74.62  ? 25  ALA A C   1 
ATOM   15    O  O   . ALA A 1 25  ? 143.198 180.920 157.678 1.00 74.62  ? 25  ALA A O   1 
ATOM   16    C  CB  . ALA A 1 25  ? 144.374 178.522 156.856 1.00 74.62  ? 25  ALA A CB  1 
ATOM   17    N  N   . SER A 1 26  ? 145.156 181.861 158.261 1.00 67.42  ? 26  SER A N   1 
ATOM   18    C  CA  . SER A 1 26  ? 144.577 183.189 158.409 1.00 67.42  ? 26  SER A CA  1 
ATOM   19    C  C   . SER A 1 26  ? 144.141 183.730 157.053 1.00 67.42  ? 26  SER A C   1 
ATOM   20    O  O   . SER A 1 26  ? 144.690 183.353 156.015 1.00 67.42  ? 26  SER A O   1 
ATOM   21    C  CB  . SER A 1 26  ? 145.587 184.130 159.060 1.00 67.42  ? 26  SER A CB  1 
ATOM   22    O  OG  . SER A 1 26  ? 146.724 184.301 158.234 1.00 67.42  ? 26  SER A OG  1 
ATOM   23    N  N   . MET A 1 27  ? 143.145 184.615 157.065 1.00 69.22  ? 27  MET A N   1 
ATOM   24    C  CA  . MET A 1 27  ? 142.573 185.147 155.836 1.00 69.22  ? 27  MET A CA  1 
ATOM   25    C  C   . MET A 1 27  ? 142.528 186.669 155.797 1.00 69.22  ? 27  MET A C   1 
ATOM   26    O  O   . MET A 1 27  ? 142.110 187.233 154.780 1.00 69.22  ? 27  MET A O   1 
ATOM   27    C  CB  . MET A 1 27  ? 141.156 184.595 155.632 1.00 69.22  ? 27  MET A CB  1 
ATOM   28    C  CG  . MET A 1 27  ? 141.107 183.094 155.400 1.00 69.22  ? 27  MET A CG  1 
ATOM   29    S  SD  . MET A 1 27  ? 139.428 182.465 155.227 1.00 69.22  ? 27  MET A SD  1 
ATOM   30    C  CE  . MET A 1 27  ? 138.990 183.125 153.622 1.00 69.22  ? 27  MET A CE  1 
ATOM   31    N  N   . ASP A 1 28  ? 142.940 187.343 156.868 1.00 59.85  ? 28  ASP A N   1 
ATOM   32    C  CA  . ASP A 1 28  ? 142.980 188.798 156.896 1.00 59.85  ? 28  ASP A CA  1 
ATOM   33    C  C   . ASP A 1 28  ? 144.310 189.367 156.419 1.00 59.85  ? 28  ASP A C   1 
ATOM   34    O  O   . ASP A 1 28  ? 144.368 190.548 156.060 1.00 59.85  ? 28  ASP A O   1 
ATOM   35    C  CB  . ASP A 1 28  ? 142.688 189.304 158.315 1.00 59.85  ? 28  ASP A CB  1 
ATOM   36    C  CG  . ASP A 1 28  ? 142.603 190.818 158.392 1.00 59.85  ? 28  ASP A CG  1 
ATOM   37    O  OD1 . ASP A 1 28  ? 141.589 191.384 157.935 1.00 59.85  ? 28  ASP A OD1 1 
ATOM   38    O  OD2 . ASP A 1 28  ? 143.554 191.442 158.909 1.00 59.85  ? 28  ASP A OD2 1 
ATOM   39    N  N   . GLU A 1 29  ? 145.368 188.562 156.388 1.00 42.11  ? 29  GLU A N   1 
ATOM   40    C  CA  . GLU A 1 29  ? 146.716 189.045 156.130 1.00 42.11  ? 29  GLU A CA  1 
ATOM   41    C  C   . GLU A 1 29  ? 147.249 188.434 154.842 1.00 42.11  ? 29  GLU A C   1 
ATOM   42    O  O   . GLU A 1 29  ? 146.867 187.320 154.473 1.00 42.11  ? 29  GLU A O   1 
ATOM   43    C  CB  . GLU A 1 29  ? 147.629 188.724 157.312 1.00 42.11  ? 29  GLU A CB  1 
ATOM   44    C  CG  . GLU A 1 29  ? 147.836 187.249 157.554 1.00 42.11  ? 29  GLU A CG  1 
ATOM   45    C  CD  . GLU A 1 29  ? 148.578 186.984 158.844 1.00 42.11  ? 29  GLU A CD  1 
ATOM   46    O  OE1 . GLU A 1 29  ? 148.861 187.956 159.575 1.00 42.11  ? 29  GLU A OE1 1 
ATOM   47    O  OE2 . GLU A 1 29  ? 148.880 185.806 159.127 1.00 42.11  ? 29  GLU A OE2 1 
ATOM   48    N  N   . ASN A 1 30  ? 148.133 189.167 154.168 1.00 33.36  ? 30  ASN A N   1 
ATOM   49    C  CA  . ASN A 1 30  ? 148.589 188.843 152.822 1.00 33.36  ? 30  ASN A CA  1 
ATOM   50    C  C   . ASN A 1 30  ? 150.091 189.076 152.745 1.00 33.36  ? 30  ASN A C   1 
ATOM   51    O  O   . ASN A 1 30  ? 150.557 190.196 152.970 1.00 33.36  ? 30  ASN A O   1 
ATOM   52    C  CB  . ASN A 1 30  ? 147.854 189.703 151.792 1.00 33.36  ? 30  ASN A CB  1 
ATOM   53    C  CG  . ASN A 1 30  ? 148.075 189.236 150.373 1.00 33.36  ? 30  ASN A CG  1 
ATOM   54    O  OD1 . ASN A 1 30  ? 148.793 188.269 150.127 1.00 33.36  ? 30  ASN A OD1 1 
ATOM   55    N  ND2 . ASN A 1 30  ? 147.455 189.925 149.426 1.00 33.36  ? 30  ASN A ND2 1 
ATOM   56    N  N   . TYR A 1 31  ? 150.844 188.026 152.408 1.00 37.45  ? 31  TYR A N   1 
ATOM   57    C  CA  . TYR A 1 31  ? 152.302 188.103 152.406 1.00 37.45  ? 31  TYR A CA  1 
ATOM   58    C  C   . TYR A 1 31  ? 152.862 189.070 151.375 1.00 37.45  ? 31  TYR A C   1 
ATOM   59    O  O   . TYR A 1 31  ? 154.073 189.315 151.382 1.00 37.45  ? 31  TYR A O   1 
ATOM   60    C  CB  . TYR A 1 31  ? 152.903 186.720 152.166 1.00 37.45  ? 31  TYR A CB  1 
ATOM   61    C  CG  . TYR A 1 31  ? 152.737 185.773 153.323 1.00 37.45  ? 31  TYR A CG  1 
ATOM   62    C  CD1 . TYR A 1 31  ? 153.601 185.810 154.402 1.00 37.45  ? 31  TYR A CD1 1 
ATOM   63    C  CD2 . TYR A 1 31  ? 151.716 184.845 153.340 1.00 37.45  ? 31  TYR A CD2 1 
ATOM   64    C  CE1 . TYR A 1 31  ? 153.452 184.948 155.460 1.00 37.45  ? 31  TYR A CE1 1 
ATOM   65    C  CE2 . TYR A 1 31  ? 151.564 183.977 154.393 1.00 37.45  ? 31  TYR A CE2 1 
ATOM   66    C  CZ  . TYR A 1 31  ? 152.431 184.036 155.451 1.00 37.45  ? 31  TYR A CZ  1 
ATOM   67    O  OH  . TYR A 1 31  ? 152.279 183.173 156.505 1.00 37.45  ? 31  TYR A OH  1 
ATOM   68    N  N   . PHE A 1 32  ? 152.032 189.614 150.490 1.00 48.92  ? 32  PHE A N   1 
ATOM   69    C  CA  . PHE A 1 32  ? 152.487 190.559 149.482 1.00 48.92  ? 32  PHE A CA  1 
ATOM   70    C  C   . PHE A 1 32  ? 151.979 191.973 149.720 1.00 48.92  ? 32  PHE A C   1 
ATOM   71    O  O   . PHE A 1 32  ? 152.320 192.870 148.945 1.00 48.92  ? 32  PHE A O   1 
ATOM   72    C  CB  . PHE A 1 32  ? 152.049 190.094 148.088 1.00 48.92  ? 32  PHE A CB  1 
ATOM   73    C  CG  . PHE A 1 32  ? 152.689 188.809 147.648 1.00 48.92  ? 32  PHE A CG  1 
ATOM   74    C  CD1 . PHE A 1 32  ? 153.942 188.805 147.070 1.00 48.92  ? 32  PHE A CD1 1 
ATOM   75    C  CD2 . PHE A 1 32  ? 152.040 187.602 147.828 1.00 48.92  ? 32  PHE A CD2 1 
ATOM   76    C  CE1 . PHE A 1 32  ? 154.530 187.624 146.671 1.00 48.92  ? 32  PHE A CE1 1 
ATOM   77    C  CE2 . PHE A 1 32  ? 152.627 186.419 147.430 1.00 48.92  ? 32  PHE A CE2 1 
ATOM   78    C  CZ  . PHE A 1 32  ? 153.872 186.431 146.853 1.00 48.92  ? 32  PHE A CZ  1 
ATOM   79    N  N   . VAL A 1 33  ? 151.169 192.191 150.758 1.00 37.43  ? 33  VAL A N   1 
ATOM   80    C  CA  . VAL A 1 33  ? 150.595 193.504 151.034 1.00 37.43  ? 33  VAL A CA  1 
ATOM   81    C  C   . VAL A 1 33  ? 150.650 193.810 152.527 1.00 37.43  ? 33  VAL A C   1 
ATOM   82    O  O   . VAL A 1 33  ? 151.024 194.918 152.927 1.00 37.43  ? 33  VAL A O   1 
ATOM   83    C  CB  . VAL A 1 33  ? 149.146 193.602 150.520 1.00 37.43  ? 33  VAL A CB  1 
ATOM   84    C  CG1 . VAL A 1 33  ? 148.513 194.904 150.977 1.00 37.43  ? 33  VAL A CG1 1 
ATOM   85    C  CG2 . VAL A 1 33  ? 149.097 193.500 149.004 1.00 37.43  ? 33  VAL A CG2 1 
ATOM   86    N  N   . ASN A 1 34  ? 150.283 192.837 153.359 1.00 31.17  ? 34  ASN A N   1 
ATOM   87    C  CA  . ASN A 1 34  ? 150.096 193.081 154.785 1.00 31.17  ? 34  ASN A CA  1 
ATOM   88    C  C   . ASN A 1 34  ? 150.080 191.760 155.538 1.00 31.17  ? 34  ASN A C   1 
ATOM   89    O  O   . ASN A 1 34  ? 149.225 190.914 155.271 1.00 31.17  ? 34  ASN A O   1 
ATOM   90    C  CB  . ASN A 1 34  ? 148.783 193.834 155.028 1.00 31.17  ? 34  ASN A CB  1 
ATOM   91    C  CG  . ASN A 1 34  ? 148.588 194.227 156.478 1.00 31.17  ? 34  ASN A CG  1 
ATOM   92    O  OD1 . ASN A 1 34  ? 149.430 193.952 157.328 1.00 31.17  ? 34  ASN A OD1 1 
ATOM   93    N  ND2 . ASN A 1 34  ? 147.462 194.865 156.768 1.00 31.17  ? 34  ASN A ND2 1 
ATOM   94    N  N   . TYR A 1 35  ? 150.996 191.593 156.490 1.00 20.19  ? 35  TYR A N   1 
ATOM   95    C  CA  . TYR A 1 35  ? 150.968 190.411 157.342 1.00 20.19  ? 35  TYR A CA  1 
ATOM   96    C  C   . TYR A 1 35  ? 151.623 190.744 158.675 1.00 20.19  ? 35  TYR A C   1 
ATOM   97    O  O   . TYR A 1 35  ? 152.081 191.864 158.903 1.00 20.19  ? 35  TYR A O   1 
ATOM   98    C  CB  . TYR A 1 35  ? 151.649 189.214 156.670 1.00 20.19  ? 35  TYR A CB  1 
ATOM   99    C  CG  . TYR A 1 35  ? 153.146 189.333 156.526 1.00 20.19  ? 35  TYR A CG  1 
ATOM   100   C  CD1 . TYR A 1 35  ? 153.711 189.990 155.449 1.00 20.19  ? 35  TYR A CD1 1 
ATOM   101   C  CD2 . TYR A 1 35  ? 153.995 188.753 157.451 1.00 20.19  ? 35  TYR A CD2 1 
ATOM   102   C  CE1 . TYR A 1 35  ? 155.078 190.088 155.317 1.00 20.19  ? 35  TYR A CE1 1 
ATOM   103   C  CE2 . TYR A 1 35  ? 155.360 188.845 157.322 1.00 20.19  ? 35  TYR A CE2 1 
ATOM   104   C  CZ  . TYR A 1 35  ? 155.896 189.514 156.256 1.00 20.19  ? 35  TYR A CZ  1 
ATOM   105   O  OH  . TYR A 1 35  ? 157.261 189.605 156.129 1.00 20.19  ? 35  TYR A OH  1 
ATOM   106   N  N   . THR A 1 36  ? 151.657 189.749 159.557 1.00 26.91  ? 36  THR A N   1 
ATOM   107   C  CA  . THR A 1 36  ? 152.167 189.904 160.913 1.00 26.91  ? 36  THR A CA  1 
ATOM   108   C  C   . THR A 1 36  ? 153.465 189.125 161.064 1.00 26.91  ? 36  THR A C   1 
ATOM   109   O  O   . THR A 1 36  ? 153.508 187.923 160.782 1.00 26.91  ? 36  THR A O   1 
ATOM   110   C  CB  . THR A 1 36  ? 151.148 189.416 161.944 1.00 26.91  ? 36  THR A CB  1 
ATOM   111   O  OG1 . THR A 1 36  ? 149.925 190.145 161.794 1.00 26.91  ? 36  THR A OG1 1 
ATOM   112   C  CG2 . THR A 1 36  ? 151.679 189.621 163.351 1.00 26.91  ? 36  THR A CG2 1 
ATOM   113   N  N   . PHE A 1 37  ? 154.514 189.805 161.510 1.00 23.77  ? 37  PHE A N   1 
ATOM   114   C  CA  . PHE A 1 37  ? 155.807 189.179 161.752 1.00 23.77  ? 37  PHE A CA  1 
ATOM   115   C  C   . PHE A 1 37  ? 155.833 188.639 163.175 1.00 23.77  ? 37  PHE A C   1 
ATOM   116   O  O   . PHE A 1 37  ? 155.242 189.235 164.082 1.00 23.77  ? 37  PHE A O   1 
ATOM   117   C  CB  . PHE A 1 37  ? 156.943 190.171 161.510 1.00 23.77  ? 37  PHE A CB  1 
ATOM   118   C  CG  . PHE A 1 37  ? 158.308 189.612 161.781 1.00 23.77  ? 37  PHE A CG  1 
ATOM   119   C  CD1 . PHE A 1 37  ? 158.827 188.608 160.990 1.00 23.77  ? 37  PHE A CD1 1 
ATOM   120   C  CD2 . PHE A 1 37  ? 159.091 190.125 162.797 1.00 23.77  ? 37  PHE A CD2 1 
ATOM   121   C  CE1 . PHE A 1 37  ? 160.085 188.099 161.228 1.00 23.77  ? 37  PHE A CE1 1 
ATOM   122   C  CE2 . PHE A 1 37  ? 160.352 189.623 163.035 1.00 23.77  ? 37  PHE A CE2 1 
ATOM   123   C  CZ  . PHE A 1 37  ? 160.849 188.609 162.248 1.00 23.77  ? 37  PHE A CZ  1 
ATOM   124   N  N   . LYS A 1 38  ? 156.505 187.509 163.364 1.00 27.06  ? 38  LYS A N   1 
ATOM   125   C  CA  . LYS A 1 38  ? 156.485 186.766 164.618 1.00 27.06  ? 38  LYS A CA  1 
ATOM   126   C  C   . LYS A 1 38  ? 157.870 186.173 164.833 1.00 27.06  ? 38  LYS A C   1 
ATOM   127   O  O   . LYS A 1 38  ? 158.128 185.032 164.439 1.00 27.06  ? 38  LYS A O   1 
ATOM   128   C  CB  . LYS A 1 38  ? 155.416 185.676 164.569 1.00 27.06  ? 38  LYS A CB  1 
ATOM   129   C  CG  . LYS A 1 38  ? 155.234 184.886 165.849 1.00 27.06  ? 38  LYS A CG  1 
ATOM   130   C  CD  . LYS A 1 38  ? 154.588 185.726 166.924 1.00 27.06  ? 38  LYS A CD  1 
ATOM   131   C  CE  . LYS A 1 38  ? 154.385 184.920 168.188 1.00 27.06  ? 38  LYS A CE  1 
ATOM   132   N  NZ  . LYS A 1 38  ? 153.403 183.824 167.970 1.00 27.06  ? 38  LYS A NZ  1 
ATOM   133   N  N   . ASP A 1 39  ? 158.757 186.946 165.453 1.00 31.80  ? 39  ASP A N   1 
ATOM   134   C  CA  . ASP A 1 39  ? 160.150 186.553 165.613 1.00 31.80  ? 39  ASP A CA  1 
ATOM   135   C  C   . ASP A 1 39  ? 160.232 185.408 166.615 1.00 31.80  ? 39  ASP A C   1 
ATOM   136   O  O   . ASP A 1 39  ? 159.578 185.445 167.662 1.00 31.80  ? 39  ASP A O   1 
ATOM   137   C  CB  . ASP A 1 39  ? 160.998 187.737 166.071 1.00 31.80  ? 39  ASP A CB  1 
ATOM   138   C  CG  . ASP A 1 39  ? 162.481 187.477 165.932 1.00 31.80  ? 39  ASP A CG  1 
ATOM   139   O  OD1 . ASP A 1 39  ? 162.851 186.372 165.487 1.00 31.80  ? 39  ASP A OD1 1 
ATOM   140   O  OD2 . ASP A 1 39  ? 163.279 188.376 166.265 1.00 31.80  ? 39  ASP A OD2 1 
ATOM   141   N  N   . ARG A 1 40  ? 161.036 184.393 166.293 1.00 36.78  ? 40  ARG A N   1 
ATOM   142   C  CA  . ARG A 1 40  ? 161.108 183.204 167.134 1.00 36.78  ? 40  ARG A CA  1 
ATOM   143   C  C   . ARG A 1 40  ? 162.244 183.285 168.141 1.00 36.78  ? 40  ARG A C   1 
ATOM   144   O  O   . ARG A 1 40  ? 162.079 182.863 169.290 1.00 36.78  ? 40  ARG A O   1 
ATOM   145   C  CB  . ARG A 1 40  ? 161.272 181.955 166.268 1.00 36.78  ? 40  ARG A CB  1 
ATOM   146   C  CG  . ARG A 1 40  ? 159.996 181.481 165.584 1.00 36.78  ? 40  ARG A CG  1 
ATOM   147   C  CD  . ARG A 1 40  ? 159.722 182.291 164.325 1.00 36.78  ? 40  ARG A CD  1 
ATOM   148   N  NE  . ARG A 1 40  ? 160.775 182.125 163.327 1.00 36.78  ? 40  ARG A NE  1 
ATOM   149   C  CZ  . ARG A 1 40  ? 160.973 182.951 162.305 1.00 36.78  ? 40  ARG A CZ  1 
ATOM   150   N  NH1 . ARG A 1 40  ? 160.198 184.014 162.148 1.00 36.78  ? 40  ARG A NH1 1 
ATOM   151   N  NH2 . ARG A 1 40  ? 161.956 182.721 161.447 1.00 36.78  ? 40  ARG A NH2 1 
ATOM   152   N  N   . SER A 1 41  ? 163.396 183.816 167.733 1.00 32.47  ? 41  SER A N   1 
ATOM   153   C  CA  . SER A 1 41  ? 164.552 183.956 168.606 1.00 32.47  ? 41  SER A CA  1 
ATOM   154   C  C   . SER A 1 41  ? 164.516 185.237 169.425 1.00 32.47  ? 41  SER A C   1 
ATOM   155   O  O   . SER A 1 41  ? 165.557 185.878 169.599 1.00 32.47  ? 41  SER A O   1 
ATOM   156   C  CB  . SER A 1 41  ? 165.841 183.902 167.786 1.00 32.47  ? 41  SER A CB  1 
ATOM   157   O  OG  . SER A 1 41  ? 166.974 184.084 168.618 1.00 32.47  ? 41  SER A OG  1 
ATOM   158   N  N   . HIS A 1 42  ? 163.344 185.628 169.924 1.00 31.38  ? 42  HIS A N   1 
ATOM   159   C  CA  . HIS A 1 42  ? 163.254 186.852 170.710 1.00 31.38  ? 42  HIS A CA  1 
ATOM   160   C  C   . HIS A 1 42  ? 163.478 186.579 172.190 1.00 31.38  ? 42  HIS A C   1 
ATOM   161   O  O   . HIS A 1 42  ? 164.334 187.212 172.821 1.00 31.38  ? 42  HIS A O   1 
ATOM   162   C  CB  . HIS A 1 42  ? 161.896 187.513 170.497 1.00 31.38  ? 42  HIS A CB  1 
ATOM   163   C  CG  . HIS A 1 42  ? 161.718 188.774 171.279 1.00 31.38  ? 42  HIS A CG  1 
ATOM   164   N  ND1 . HIS A 1 42  ? 162.323 189.960 170.924 1.00 31.38  ? 42  HIS A ND1 1 
ATOM   165   C  CD2 . HIS A 1 42  ? 161.017 189.032 172.408 1.00 31.38  ? 42  HIS A CD2 1 
ATOM   166   C  CE1 . HIS A 1 42  ? 161.995 190.896 171.796 1.00 31.38  ? 42  HIS A CE1 1 
ATOM   167   N  NE2 . HIS A 1 42  ? 161.203 190.359 172.706 1.00 31.38  ? 42  HIS A NE2 1 
ATOM   168   N  N   . SER A 1 43  ? 162.708 185.650 172.761 1.00 30.99  ? 43  SER A N   1 
ATOM   169   C  CA  . SER A 1 43  ? 162.849 185.325 174.176 1.00 30.99  ? 43  SER A CA  1 
ATOM   170   C  C   . SER A 1 43  ? 164.275 184.913 174.506 1.00 30.99  ? 43  SER A C   1 
ATOM   171   O  O   . SER A 1 43  ? 164.824 185.311 175.541 1.00 30.99  ? 43  SER A O   1 
ATOM   172   C  CB  . SER A 1 43  ? 161.870 184.217 174.553 1.00 30.99  ? 43  SER A CB  1 
ATOM   173   O  OG  . SER A 1 43  ? 162.184 183.017 173.869 1.00 30.99  ? 43  SER A OG  1 
ATOM   174   N  N   . GLY A 1 44  ? 164.892 184.117 173.636 1.00 31.56  ? 44  GLY A N   1 
ATOM   175   C  CA  . GLY A 1 44  ? 166.290 183.786 173.826 1.00 31.56  ? 44  GLY A CA  1 
ATOM   176   C  C   . GLY A 1 44  ? 167.179 185.013 173.808 1.00 31.56  ? 44  GLY A C   1 
ATOM   177   O  O   . GLY A 1 44  ? 167.952 185.241 174.736 1.00 31.56  ? 44  GLY A O   1 
ATOM   178   N  N   . ARG A 1 45  ? 167.054 185.839 172.768 1.00 31.22  ? 45  ARG A N   1 
ATOM   179   C  CA  . ARG A 1 45  ? 167.961 186.970 172.594 1.00 31.22  ? 45  ARG A CA  1 
ATOM   180   C  C   . ARG A 1 45  ? 167.873 187.946 173.761 1.00 31.22  ? 45  ARG A C   1 
ATOM   181   O  O   . ARG A 1 45  ? 168.886 188.512 174.186 1.00 31.22  ? 45  ARG A O   1 
ATOM   182   C  CB  . ARG A 1 45  ? 167.665 187.671 171.268 1.00 31.22  ? 45  ARG A CB  1 
ATOM   183   C  CG  . ARG A 1 45  ? 168.587 188.829 170.944 1.00 31.22  ? 45  ARG A CG  1 
ATOM   184   C  CD  . ARG A 1 45  ? 168.323 189.339 169.541 1.00 31.22  ? 45  ARG A CD  1 
ATOM   185   N  NE  . ARG A 1 45  ? 166.956 189.822 169.383 1.00 31.22  ? 45  ARG A NE  1 
ATOM   186   C  CZ  . ARG A 1 45  ? 166.053 189.245 168.599 1.00 31.22  ? 45  ARG A CZ  1 
ATOM   187   N  NH1 . ARG A 1 45  ? 166.374 188.166 167.901 1.00 31.22  ? 45  ARG A NH1 1 
ATOM   188   N  NH2 . ARG A 1 45  ? 164.831 189.748 168.509 1.00 31.22  ? 45  ARG A NH2 1 
ATOM   189   N  N   . VAL A 1 46  ? 166.671 188.155 174.302 1.00 28.41  ? 46  VAL A N   1 
ATOM   190   C  CA  . VAL A 1 46  ? 166.572 189.017 175.476 1.00 28.41  ? 46  VAL A CA  1 
ATOM   191   C  C   . VAL A 1 46  ? 167.060 188.282 176.721 1.00 28.41  ? 46  VAL A C   1 
ATOM   192   O  O   . VAL A 1 46  ? 167.589 188.904 177.653 1.00 28.41  ? 46  VAL A O   1 
ATOM   193   C  CB  . VAL A 1 46  ? 165.136 189.549 175.642 1.00 28.41  ? 46  VAL A CB  1 
ATOM   194   C  CG1 . VAL A 1 46  ? 164.176 188.425 175.968 1.00 28.41  ? 46  VAL A CG1 1 
ATOM   195   C  CG2 . VAL A 1 46  ? 165.089 190.625 176.710 1.00 28.41  ? 46  VAL A CG2 1 
ATOM   196   N  N   . ALA A 1 47  ? 166.925 186.952 176.748 1.00 31.21  ? 47  ALA A N   1 
ATOM   197   C  CA  . ALA A 1 47  ? 167.407 186.179 177.888 1.00 31.21  ? 47  ALA A CA  1 
ATOM   198   C  C   . ALA A 1 47  ? 168.924 186.270 178.011 1.00 31.21  ? 47  ALA A C   1 
ATOM   199   O  O   . ALA A 1 47  ? 169.451 186.565 179.089 1.00 31.21  ? 47  ALA A O   1 
ATOM   200   C  CB  . ALA A 1 47  ? 166.958 184.723 177.766 1.00 31.21  ? 47  ALA A CB  1 
ATOM   201   N  N   . GLN A 1 48  ? 169.647 186.022 176.914 1.00 31.38  ? 48  GLN A N   1 
ATOM   202   C  CA  . GLN A 1 48  ? 171.097 186.177 176.952 1.00 31.38  ? 48  GLN A CA  1 
ATOM   203   C  C   . GLN A 1 48  ? 171.504 187.642 176.945 1.00 31.38  ? 48  GLN A C   1 
ATOM   204   O  O   . GLN A 1 48  ? 172.648 187.965 177.282 1.00 31.38  ? 48  GLN A O   1 
ATOM   205   C  CB  . GLN A 1 48  ? 171.771 185.446 175.788 1.00 31.38  ? 48  GLN A CB  1 
ATOM   206   C  CG  . GLN A 1 48  ? 171.726 183.926 175.878 1.00 31.38  ? 48  GLN A CG  1 
ATOM   207   C  CD  . GLN A 1 48  ? 170.590 183.313 175.090 1.00 31.38  ? 48  GLN A CD  1 
ATOM   208   O  OE1 . GLN A 1 48  ? 170.106 183.899 174.121 1.00 31.38  ? 48  GLN A OE1 1 
ATOM   209   N  NE2 . GLN A 1 48  ? 170.154 182.129 175.502 1.00 31.38  ? 48  GLN A NE2 1 
ATOM   210   N  N   . GLY A 1 49  ? 170.595 188.539 176.560 1.00 29.90  ? 49  GLY A N   1 
ATOM   211   C  CA  . GLY A 1 49  ? 170.876 189.956 176.716 1.00 29.90  ? 49  GLY A CA  1 
ATOM   212   C  C   . GLY A 1 49  ? 171.001 190.350 178.175 1.00 29.90  ? 49  GLY A C   1 
ATOM   213   O  O   . GLY A 1 49  ? 172.022 190.899 178.602 1.00 29.90  ? 49  GLY A O   1 
ATOM   214   N  N   . ILE A 1 50  ? 169.967 190.054 178.965 1.00 31.86  ? 50  ILE A N   1 
ATOM   215   C  CA  . ILE A 1 50  ? 170.017 190.332 180.397 1.00 31.86  ? 50  ILE A CA  1 
ATOM   216   C  C   . ILE A 1 50  ? 171.083 189.479 181.075 1.00 31.86  ? 50  ILE A C   1 
ATOM   217   O  O   . ILE A 1 50  ? 171.790 189.944 181.975 1.00 31.86  ? 50  ILE A O   1 
ATOM   218   C  CB  . ILE A 1 50  ? 168.631 190.111 181.025 1.00 31.86  ? 50  ILE A CB  1 
ATOM   219   C  CG1 . ILE A 1 50  ? 167.637 191.144 180.495 1.00 31.86  ? 50  ILE A CG1 1 
ATOM   220   C  CG2 . ILE A 1 50  ? 168.717 190.152 182.536 1.00 31.86  ? 50  ILE A CG2 1 
ATOM   221   C  CD1 . ILE A 1 50  ? 166.207 190.844 180.855 1.00 31.86  ? 50  ILE A CD1 1 
ATOM   222   N  N   . MET A 1 51  ? 171.212 188.219 180.659 1.00 34.17  ? 51  MET A N   1 
ATOM   223   C  CA  . MET A 1 51  ? 172.256 187.355 181.198 1.00 34.17  ? 51  MET A CA  1 
ATOM   224   C  C   . MET A 1 51  ? 173.641 187.947 180.973 1.00 34.17  ? 51  MET A C   1 
ATOM   225   O  O   . MET A 1 51  ? 174.529 187.806 181.820 1.00 34.17  ? 51  MET A O   1 
ATOM   226   C  CB  . MET A 1 51  ? 172.166 185.975 180.550 1.00 34.17  ? 51  MET A CB  1 
ATOM   227   C  CG  . MET A 1 51  ? 173.159 184.963 181.076 1.00 34.17  ? 51  MET A CG  1 
ATOM   228   S  SD  . MET A 1 51  ? 173.064 183.413 180.163 1.00 34.17  ? 51  MET A SD  1 
ATOM   229   C  CE  . MET A 1 51  ? 171.471 182.797 180.698 1.00 34.17  ? 51  MET A CE  1 
ATOM   230   N  N   . LYS A 1 52  ? 173.837 188.625 179.843 1.00 36.47  ? 52  LYS A N   1 
ATOM   231   C  CA  . LYS A 1 52  ? 175.162 189.065 179.421 1.00 36.47  ? 52  LYS A CA  1 
ATOM   232   C  C   . LYS A 1 52  ? 175.513 190.453 179.950 1.00 36.47  ? 52  LYS A C   1 
ATOM   233   O  O   . LYS A 1 52  ? 176.479 190.607 180.702 1.00 36.47  ? 52  LYS A O   1 
ATOM   234   C  CB  . LYS A 1 52  ? 175.253 189.037 177.893 1.00 36.47  ? 52  LYS A CB  1 
ATOM   235   C  CG  . LYS A 1 52  ? 176.610 189.426 177.347 1.00 36.47  ? 52  LYS A CG  1 
ATOM   236   C  CD  . LYS A 1 52  ? 176.666 189.234 175.842 1.00 36.47  ? 52  LYS A CD  1 
ATOM   237   C  CE  . LYS A 1 52  ? 175.849 190.292 175.124 1.00 36.47  ? 52  LYS A CE  1 
ATOM   238   N  NZ  . LYS A 1 52  ? 176.465 191.641 175.258 1.00 36.47  ? 52  LYS A NZ  1 
ATOM   239   N  N   . LEU A 1 53  ? 174.749 191.475 179.563 1.00 38.37  ? 53  LEU A N   1 
ATOM   240   C  CA  . LEU A 1 53  ? 175.120 192.849 179.880 1.00 38.37  ? 53  LEU A CA  1 
ATOM   241   C  C   . LEU A 1 53  ? 174.684 193.279 181.277 1.00 38.37  ? 53  LEU A C   1 
ATOM   242   O  O   . LEU A 1 53  ? 174.791 194.464 181.611 1.00 38.37  ? 53  LEU A O   1 
ATOM   243   C  CB  . LEU A 1 53  ? 174.569 193.809 178.820 1.00 38.37  ? 53  LEU A CB  1 
ATOM   244   C  CG  . LEU A 1 53  ? 173.068 193.928 178.559 1.00 38.37  ? 53  LEU A CG  1 
ATOM   245   C  CD1 . LEU A 1 53  ? 172.414 194.940 179.480 1.00 38.37  ? 53  LEU A CD1 1 
ATOM   246   C  CD2 . LEU A 1 53  ? 172.839 194.302 177.112 1.00 38.37  ? 53  LEU A CD2 1 
ATOM   247   N  N   . CYS A 1 54  ? 174.204 192.352 182.099 1.00 40.24  ? 54  CYS A N   1 
ATOM   248   C  CA  . CYS A 1 54  ? 173.921 192.633 183.499 1.00 40.24  ? 54  CYS A CA  1 
ATOM   249   C  C   . CYS A 1 54  ? 174.886 191.971 184.465 1.00 40.24  ? 54  CYS A C   1 
ATOM   250   O  O   . CYS A 1 54  ? 175.725 192.664 185.041 1.00 40.24  ? 54  CYS A O   1 
ATOM   251   C  CB  . CYS A 1 54  ? 172.496 192.199 183.869 1.00 40.24  ? 54  CYS A CB  1 
ATOM   252   S  SG  . CYS A 1 54  ? 172.108 192.388 185.622 1.00 40.24  ? 54  CYS A SG  1 
ATOM   253   N  N   . LEU A 1 55  ? 174.801 190.655 184.654 1.00 40.35  ? 55  LEU A N   1 
ATOM   254   C  CA  . LEU A 1 55  ? 175.636 189.973 185.630 1.00 40.35  ? 55  LEU A CA  1 
ATOM   255   C  C   . LEU A 1 55  ? 177.050 189.713 185.121 1.00 40.35  ? 55  LEU A C   1 
ATOM   256   O  O   . LEU A 1 55  ? 177.648 188.694 185.480 1.00 40.35  ? 55  LEU A O   1 
ATOM   257   C  CB  . LEU A 1 55  ? 174.966 188.656 186.057 1.00 40.35  ? 55  LEU A CB  1 
ATOM   258   C  CG  . LEU A 1 55  ? 175.411 187.958 187.345 1.00 40.35  ? 55  LEU A CG  1 
ATOM   259   C  CD1 . LEU A 1 55  ? 175.175 188.866 188.538 1.00 40.35  ? 55  LEU A CD1 1 
ATOM   260   C  CD2 . LEU A 1 55  ? 174.658 186.659 187.524 1.00 40.35  ? 55  LEU A CD2 1 
ATOM   261   N  N   . GLU A 1 56  ? 177.588 190.603 184.286 1.00 49.33  ? 56  GLU A N   1 
ATOM   262   C  CA  . GLU A 1 56  ? 178.973 190.534 183.836 1.00 49.33  ? 56  GLU A CA  1 
ATOM   263   C  C   . GLU A 1 56  ? 179.659 191.891 183.880 1.00 49.33  ? 56  GLU A C   1 
ATOM   264   O  O   . GLU A 1 56  ? 180.662 192.050 184.585 1.00 49.33  ? 56  GLU A O   1 
ATOM   265   C  CB  . GLU A 1 56  ? 179.048 189.980 182.411 1.00 49.33  ? 56  GLU A CB  1 
ATOM   266   C  CG  . GLU A 1 56  ? 178.624 188.532 182.275 1.00 49.33  ? 56  GLU A CG  1 
ATOM   267   C  CD  . GLU A 1 56  ? 179.580 187.582 182.961 1.00 49.33  ? 56  GLU A CD  1 
ATOM   268   O  OE1 . GLU A 1 56  ? 180.788 187.891 183.017 1.00 49.33  ? 56  GLU A OE1 1 
ATOM   269   O  OE2 . GLU A 1 56  ? 179.123 186.524 183.441 1.00 49.33  ? 56  GLU A OE2 1 
ATOM   270   N  N   . GLU A 1 57  ? 179.141 192.871 183.141 1.00 52.34  ? 57  GLU A N   1 
ATOM   271   C  CA  . GLU A 1 57  ? 179.634 194.237 183.204 1.00 52.34  ? 57  GLU A CA  1 
ATOM   272   C  C   . GLU A 1 57  ? 179.016 195.040 184.337 1.00 52.34  ? 57  GLU A C   1 
ATOM   273   O  O   . GLU A 1 57  ? 179.561 196.090 184.697 1.00 52.34  ? 57  GLU A O   1 
ATOM   274   C  CB  . GLU A 1 57  ? 179.369 194.964 181.876 1.00 52.34  ? 57  GLU A CB  1 
ATOM   275   C  CG  . GLU A 1 57  ? 180.157 194.431 180.692 1.00 52.34  ? 57  GLU A CG  1 
ATOM   276   C  CD  . GLU A 1 57  ? 179.497 193.231 180.042 1.00 52.34  ? 57  GLU A CD  1 
ATOM   277   O  OE1 . GLU A 1 57  ? 178.399 192.841 180.491 1.00 52.34  ? 57  GLU A OE1 1 
ATOM   278   O  OE2 . GLU A 1 57  ? 180.072 192.682 179.080 1.00 52.34  ? 57  GLU A OE2 1 
ATOM   279   N  N   . GLU A 1 58  ? 177.906 194.569 184.908 1.00 56.12  ? 58  GLU A N   1 
ATOM   280   C  CA  . GLU A 1 58  ? 177.152 195.305 185.924 1.00 56.12  ? 58  GLU A CA  1 
ATOM   281   C  C   . GLU A 1 58  ? 176.823 196.715 185.443 1.00 56.12  ? 58  GLU A C   1 
ATOM   282   O  O   . GLU A 1 58  ? 177.400 197.705 185.899 1.00 56.12  ? 58  GLU A O   1 
ATOM   283   C  CB  . GLU A 1 58  ? 177.890 195.334 187.265 1.00 56.12  ? 58  GLU A CB  1 
ATOM   284   C  CG  . GLU A 1 58  ? 177.076 195.946 188.397 1.00 56.12  ? 58  GLU A CG  1 
ATOM   285   C  CD  . GLU A 1 58  ? 175.841 195.130 188.734 1.00 56.12  ? 58  GLU A CD  1 
ATOM   286   O  OE1 . GLU A 1 58  ? 175.862 193.898 188.533 1.00 56.12  ? 58  GLU A OE1 1 
ATOM   287   O  OE2 . GLU A 1 58  ? 174.841 195.726 189.184 1.00 56.12  ? 58  GLU A OE2 1 
ATOM   288   N  N   . LEU A 1 59  ? 175.900 196.803 184.494 1.00 45.79  ? 59  LEU A N   1 
ATOM   289   C  CA  . LEU A 1 59  ? 175.453 198.077 183.961 1.00 45.79  ? 59  LEU A CA  1 
ATOM   290   C  C   . LEU A 1 59  ? 173.985 198.293 184.297 1.00 45.79  ? 59  LEU A C   1 
ATOM   291   O  O   . LEU A 1 59  ? 173.230 197.341 184.508 1.00 45.79  ? 59  LEU A O   1 
ATOM   292   C  CB  . LEU A 1 59  ? 175.657 198.133 182.447 1.00 45.79  ? 59  LEU A CB  1 
ATOM   293   C  CG  . LEU A 1 59  ? 177.105 198.132 181.956 1.00 45.79  ? 59  LEU A CG  1 
ATOM   294   C  CD1 . LEU A 1 59  ? 177.157 197.996 180.446 1.00 45.79  ? 59  LEU A CD1 1 
ATOM   295   C  CD2 . LEU A 1 59  ? 177.814 199.400 182.402 1.00 45.79  ? 59  LEU A CD2 1 
ATOM   296   N  N   . PHE A 1 60  ? 173.594 199.565 184.360 1.00 39.31  ? 60  PHE A N   1 
ATOM   297   C  CA  . PHE A 1 60  ? 172.207 199.959 184.590 1.00 39.31  ? 60  PHE A CA  1 
ATOM   298   C  C   . PHE A 1 60  ? 171.700 199.460 185.939 1.00 39.31  ? 60  PHE A C   1 
ATOM   299   O  O   . PHE A 1 60  ? 170.527 199.109 186.081 1.00 39.31  ? 60  PHE A O   1 
ATOM   300   C  CB  . PHE A 1 60  ? 171.301 199.463 183.461 1.00 39.31  ? 60  PHE A CB  1 
ATOM   301   C  CG  . PHE A 1 60  ? 171.739 199.915 182.099 1.00 39.31  ? 60  PHE A CG  1 
ATOM   302   C  CD1 . PHE A 1 60  ? 171.510 201.208 181.672 1.00 39.31  ? 60  PHE A CD1 1 
ATOM   303   C  CD2 . PHE A 1 60  ? 172.384 199.038 181.243 1.00 39.31  ? 60  PHE A CD2 1 
ATOM   304   C  CE1 . PHE A 1 60  ? 171.922 201.619 180.423 1.00 39.31  ? 60  PHE A CE1 1 
ATOM   305   C  CE2 . PHE A 1 60  ? 172.794 199.443 179.991 1.00 39.31  ? 60  PHE A CE2 1 
ATOM   306   C  CZ  . PHE A 1 60  ? 172.560 200.733 179.580 1.00 39.31  ? 60  PHE A CZ  1 
ATOM   307   N  N   . ALA A 1 61  ? 172.587 199.419 186.933 1.00 34.38  ? 61  ALA A N   1 
ATOM   308   C  CA  . ALA A 1 61  ? 172.213 198.958 188.263 1.00 34.38  ? 61  ALA A CA  1 
ATOM   309   C  C   . ALA A 1 61  ? 171.137 199.860 188.847 1.00 34.38  ? 61  ALA A C   1 
ATOM   310   O  O   . ALA A 1 61  ? 171.281 201.085 188.865 1.00 34.38  ? 61  ALA A O   1 
ATOM   311   C  CB  . ALA A 1 61  ? 173.435 198.931 189.177 1.00 34.38  ? 61  ALA A CB  1 
ATOM   312   N  N   . ASP A 1 62  ? 170.057 199.253 189.326 1.00 30.04  ? 62  ASP A N   1 
ATOM   313   C  CA  . ASP A 1 62  ? 168.886 200.004 189.755 1.00 30.04  ? 62  ASP A CA  1 
ATOM   314   C  C   . ASP A 1 62  ? 168.724 200.030 191.266 1.00 30.04  ? 62  ASP A C   1 
ATOM   315   O  O   . ASP A 1 62  ? 168.806 201.103 191.874 1.00 30.04  ? 62  ASP A O   1 
ATOM   316   C  CB  . ASP A 1 62  ? 167.629 199.416 189.096 1.00 30.04  ? 62  ASP A CB  1 
ATOM   317   C  CG  . ASP A 1 62  ? 166.421 200.313 189.239 1.00 30.04  ? 62  ASP A CG  1 
ATOM   318   O  OD1 . ASP A 1 62  ? 166.540 201.390 189.858 1.00 30.04  ? 62  ASP A OD1 1 
ATOM   319   O  OD2 . ASP A 1 62  ? 165.344 199.941 188.728 1.00 30.04  ? 62  ASP A OD2 1 
ATOM   320   N  N   . VAL A 1 63  ? 168.492 198.879 191.892 1.00 29.82  ? 63  VAL A N   1 
ATOM   321   C  CA  . VAL A 1 63  ? 168.229 198.794 193.322 1.00 29.82  ? 63  VAL A CA  1 
ATOM   322   C  C   . VAL A 1 63  ? 169.397 198.079 193.985 1.00 29.82  ? 63  VAL A C   1 
ATOM   323   O  O   . VAL A 1 63  ? 170.136 197.337 193.330 1.00 29.82  ? 63  VAL A O   1 
ATOM   324   C  CB  . VAL A 1 63  ? 166.901 198.062 193.607 1.00 29.82  ? 63  VAL A CB  1 
ATOM   325   C  CG1 . VAL A 1 63  ? 167.032 196.577 193.304 1.00 29.82  ? 63  VAL A CG1 1 
ATOM   326   C  CG2 . VAL A 1 63  ? 166.431 198.304 195.034 1.00 29.82  ? 63  VAL A CG2 1 
ATOM   327   N  N   . THR A 1 64  ? 169.567 198.308 195.283 1.00 38.32  ? 64  THR A N   1 
ATOM   328   C  CA  . THR A 1 64  ? 170.622 197.670 196.056 1.00 38.32  ? 64  THR A CA  1 
ATOM   329   C  C   . THR A 1 64  ? 170.002 196.850 197.180 1.00 38.32  ? 64  THR A C   1 
ATOM   330   O  O   . THR A 1 64  ? 169.281 197.390 198.025 1.00 38.32  ? 64  THR A O   1 
ATOM   331   C  CB  . THR A 1 64  ? 171.586 198.711 196.626 1.00 38.32  ? 64  THR A CB  1 
ATOM   332   O  OG1 . THR A 1 64  ? 172.154 199.473 195.553 1.00 38.32  ? 64  THR A OG1 1 
ATOM   333   C  CG2 . THR A 1 64  ? 172.704 198.030 197.388 1.00 38.32  ? 64  THR A CG2 1 
ATOM   334   N  N   . ILE A 1 65  ? 170.277 195.548 197.179 1.00 39.49  ? 65  ILE A N   1 
ATOM   335   C  CA  . ILE A 1 65  ? 169.762 194.620 198.177 1.00 39.49  ? 65  ILE A CA  1 
ATOM   336   C  C   . ILE A 1 65  ? 170.923 194.167 199.047 1.00 39.49  ? 65  ILE A C   1 
ATOM   337   O  O   . ILE A 1 65  ? 171.949 193.711 198.531 1.00 39.49  ? 65  ILE A O   1 
ATOM   338   C  CB  . ILE A 1 65  ? 169.064 193.413 197.526 1.00 39.49  ? 65  ILE A CB  1 
ATOM   339   C  CG1 . ILE A 1 65  ? 167.818 193.868 196.768 1.00 39.49  ? 65  ILE A CG1 1 
ATOM   340   C  CG2 . ILE A 1 65  ? 168.705 192.375 198.568 1.00 39.49  ? 65  ILE A CG2 1 
ATOM   341   C  CD1 . ILE A 1 65  ? 167.205 192.796 195.912 1.00 39.49  ? 65  ILE A CD1 1 
ATOM   342   N  N   . SER A 1 66  ? 170.763 194.292 200.360 1.00 45.77  ? 66  SER A N   1 
ATOM   343   C  CA  . SER A 1 66  ? 171.805 193.954 201.320 1.00 45.77  ? 66  SER A CA  1 
ATOM   344   C  C   . SER A 1 66  ? 171.428 192.664 202.034 1.00 45.77  ? 66  SER A C   1 
ATOM   345   O  O   . SER A 1 66  ? 170.373 192.590 202.671 1.00 45.77  ? 66  SER A O   1 
ATOM   346   C  CB  . SER A 1 66  ? 172.008 195.084 202.327 1.00 45.77  ? 66  SER A CB  1 
ATOM   347   O  OG  . SER A 1 66  ? 173.000 194.746 203.278 1.00 45.77  ? 66  SER A OG  1 
ATOM   348   N  N   . VAL A 1 67  ? 172.289 191.656 201.924 1.00 49.76  ? 67  VAL A N   1 
ATOM   349   C  CA  . VAL A 1 67  ? 172.121 190.382 202.613 1.00 49.76  ? 67  VAL A CA  1 
ATOM   350   C  C   . VAL A 1 67  ? 173.200 190.287 203.679 1.00 49.76  ? 67  VAL A C   1 
ATOM   351   O  O   . VAL A 1 67  ? 174.394 190.347 203.360 1.00 49.76  ? 67  VAL A O   1 
ATOM   352   C  CB  . VAL A 1 67  ? 172.207 189.187 201.651 1.00 49.76  ? 67  VAL A CB  1 
ATOM   353   C  CG1 . VAL A 1 67  ? 172.181 187.888 202.426 1.00 49.76  ? 67  VAL A CG1 1 
ATOM   354   C  CG2 . VAL A 1 67  ? 171.070 189.234 200.653 1.00 49.76  ? 67  VAL A CG2 1 
ATOM   355   N  N   . GLU A 1 68  ? 172.784 190.137 204.937 1.00 54.29  ? 68  GLU A N   1 
ATOM   356   C  CA  . GLU A 1 68  ? 173.702 190.121 206.077 1.00 54.29  ? 68  GLU A CA  1 
ATOM   357   C  C   . GLU A 1 68  ? 174.580 191.370 206.093 1.00 54.29  ? 68  GLU A C   1 
ATOM   358   O  O   . GLU A 1 68  ? 174.293 192.351 206.780 1.00 54.29  ? 68  GLU A O   1 
ATOM   359   C  CB  . GLU A 1 68  ? 174.557 188.854 206.084 1.00 54.29  ? 68  GLU A CB  1 
ATOM   360   C  CG  . GLU A 1 68  ? 173.782 187.580 206.369 1.00 54.29  ? 68  GLU A CG  1 
ATOM   361   C  CD  . GLU A 1 68  ? 174.665 186.349 206.350 1.00 54.29  ? 68  GLU A CD  1 
ATOM   362   O  OE1 . GLU A 1 68  ? 175.854 186.478 205.989 1.00 54.29  ? 68  GLU A OE1 1 
ATOM   363   O  OE2 . GLU A 1 68  ? 174.172 185.254 206.694 1.00 54.29  ? 68  GLU A OE2 1 
ATOM   364   N  N   . GLY A 1 69  ? 175.666 191.328 205.326 1.00 51.77  ? 69  GLY A N   1 
ATOM   365   C  CA  . GLY A 1 69  ? 176.558 192.467 205.236 1.00 51.77  ? 69  GLY A CA  1 
ATOM   366   C  C   . GLY A 1 69  ? 177.192 192.656 203.878 1.00 51.77  ? 69  GLY A C   1 
ATOM   367   O  O   . GLY A 1 69  ? 178.230 193.317 203.774 1.00 51.77  ? 69  GLY A O   1 
ATOM   368   N  N   . ARG A 1 70  ? 176.594 192.097 202.830 1.00 50.95  ? 70  ARG A N   1 
ATOM   369   C  CA  . ARG A 1 70  ? 177.123 192.182 201.478 1.00 50.95  ? 70  ARG A CA  1 
ATOM   370   C  C   . ARG A 1 70  ? 176.175 193.004 200.618 1.00 50.95  ? 70  ARG A C   1 
ATOM   371   O  O   . ARG A 1 70  ? 174.954 192.927 200.777 1.00 50.95  ? 70  ARG A O   1 
ATOM   372   C  CB  . ARG A 1 70  ? 177.318 190.787 200.878 1.00 50.95  ? 70  ARG A CB  1 
ATOM   373   C  CG  . ARG A 1 70  ? 177.970 190.779 199.510 1.00 50.95  ? 70  ARG A CG  1 
ATOM   374   C  CD  . ARG A 1 70  ? 178.205 189.358 199.036 1.00 50.95  ? 70  ARG A CD  1 
ATOM   375   N  NE  . ARG A 1 70  ? 178.760 189.314 197.689 1.00 50.95  ? 70  ARG A NE  1 
ATOM   376   C  CZ  . ARG A 1 70  ? 179.046 188.192 197.037 1.00 50.95  ? 70  ARG A CZ  1 
ATOM   377   N  NH1 . ARG A 1 70  ? 178.826 187.016 197.608 1.00 50.95  ? 70  ARG A NH1 1 
ATOM   378   N  NH2 . ARG A 1 70  ? 179.548 188.247 195.811 1.00 50.95  ? 70  ARG A NH2 1 
ATOM   379   N  N   . GLU A 1 71  ? 176.742 193.792 199.707 1.00 49.65  ? 71  GLU A N   1 
ATOM   380   C  CA  . GLU A 1 71  ? 175.976 194.681 198.845 1.00 49.65  ? 71  GLU A CA  1 
ATOM   381   C  C   . GLU A 1 71  ? 175.702 193.981 197.518 1.00 49.65  ? 71  GLU A C   1 
ATOM   382   O  O   . GLU A 1 71  ? 176.621 193.439 196.894 1.00 49.65  ? 71  GLU A O   1 
ATOM   383   C  CB  . GLU A 1 71  ? 176.729 195.991 198.620 1.00 49.65  ? 71  GLU A CB  1 
ATOM   384   C  CG  . GLU A 1 71  ? 176.989 196.792 199.888 1.00 49.65  ? 71  GLU A CG  1 
ATOM   385   C  CD  . GLU A 1 71  ? 175.719 197.304 200.530 1.00 49.65  ? 71  GLU A CD  1 
ATOM   386   O  OE1 . GLU A 1 71  ? 174.746 197.578 199.799 1.00 49.65  ? 71  GLU A OE1 1 
ATOM   387   O  OE2 . GLU A 1 71  ? 175.692 197.434 201.770 1.00 49.65  ? 71  GLU A OE2 1 
ATOM   388   N  N   . PHE A 1 72  ? 174.444 194.001 197.088 1.00 39.54  ? 72  PHE A N   1 
ATOM   389   C  CA  . PHE A 1 72  ? 174.001 193.349 195.861 1.00 39.54  ? 72  PHE A CA  1 
ATOM   390   C  C   . PHE A 1 72  ? 173.339 194.371 194.948 1.00 39.54  ? 72  PHE A C   1 
ATOM   391   O  O   . PHE A 1 72  ? 172.171 194.719 195.147 1.00 39.54  ? 72  PHE A O   1 
ATOM   392   C  CB  . PHE A 1 72  ? 173.039 192.207 196.179 1.00 39.54  ? 72  PHE A CB  1 
ATOM   393   C  CG  . PHE A 1 72  ? 173.716 190.972 196.683 1.00 39.54  ? 72  PHE A CG  1 
ATOM   394   C  CD1 . PHE A 1 72  ? 175.033 190.720 196.375 1.00 39.54  ? 72  PHE A CD1 1 
ATOM   395   C  CD2 . PHE A 1 72  ? 173.050 190.084 197.496 1.00 39.54  ? 72  PHE A CD2 1 
ATOM   396   C  CE1 . PHE A 1 72  ? 175.656 189.580 196.836 1.00 39.54  ? 72  PHE A CE1 1 
ATOM   397   C  CE2 . PHE A 1 72  ? 173.679 188.952 197.966 1.00 39.54  ? 72  PHE A CE2 1 
ATOM   398   C  CZ  . PHE A 1 72  ? 174.981 188.702 197.635 1.00 39.54  ? 72  PHE A CZ  1 
ATOM   399   N  N   . GLN A 1 73  ? 174.082 194.843 193.952 1.00 38.53  ? 73  GLN A N   1 
ATOM   400   C  CA  . GLN A 1 73  ? 173.557 195.775 192.958 1.00 38.53  ? 73  GLN A CA  1 
ATOM   401   C  C   . GLN A 1 73  ? 172.724 194.971 191.969 1.00 38.53  ? 73  GLN A C   1 
ATOM   402   O  O   . GLN A 1 73  ? 173.264 194.318 191.074 1.00 38.53  ? 73  GLN A O   1 
ATOM   403   C  CB  . GLN A 1 73  ? 174.693 196.513 192.261 1.00 38.53  ? 73  GLN A CB  1 
ATOM   404   C  CG  . GLN A 1 73  ? 175.586 197.315 193.195 1.00 38.53  ? 73  GLN A CG  1 
ATOM   405   C  CD  . GLN A 1 73  ? 174.865 198.476 193.848 1.00 38.53  ? 73  GLN A CD  1 
ATOM   406   O  OE1 . GLN A 1 73  ? 174.042 199.142 193.221 1.00 38.53  ? 73  GLN A OE1 1 
ATOM   407   N  NE2 . GLN A 1 73  ? 175.175 198.730 195.114 1.00 38.53  ? 73  GLN A NE2 1 
ATOM   408   N  N   . LEU A 1 74  ? 171.405 195.014 192.126 1.00 30.40  ? 74  LEU A N   1 
ATOM   409   C  CA  . LEU A 1 74  ? 170.501 194.211 191.317 1.00 30.40  ? 74  LEU A CA  1 
ATOM   410   C  C   . LEU A 1 74  ? 169.519 195.105 190.572 1.00 30.40  ? 74  LEU A C   1 
ATOM   411   O  O   . LEU A 1 74  ? 169.272 196.251 190.948 1.00 30.40  ? 74  LEU A O   1 
ATOM   412   C  CB  . LEU A 1 74  ? 169.743 193.200 192.183 1.00 30.40  ? 74  LEU A CB  1 
ATOM   413   C  CG  . LEU A 1 74  ? 170.605 192.132 192.850 1.00 30.40  ? 74  LEU A CG  1 
ATOM   414   C  CD1 . LEU A 1 74  ? 169.756 191.257 193.749 1.00 30.40  ? 74  LEU A CD1 1 
ATOM   415   C  CD2 . LEU A 1 74  ? 171.323 191.302 191.806 1.00 30.40  ? 74  LEU A CD2 1 
ATOM   416   N  N   . HIS A 1 75  ? 168.951 194.557 189.502 1.00 33.00  ? 75  HIS A N   1 
ATOM   417   C  CA  . HIS A 1 75  ? 167.974 195.254 188.677 1.00 33.00  ? 75  HIS A CA  1 
ATOM   418   C  C   . HIS A 1 75  ? 166.579 194.933 189.186 1.00 33.00  ? 75  HIS A C   1 
ATOM   419   O  O   . HIS A 1 75  ? 166.349 193.849 189.726 1.00 33.00  ? 75  HIS A O   1 
ATOM   420   C  CB  . HIS A 1 75  ? 168.103 194.847 187.211 1.00 33.00  ? 75  HIS A CB  1 
ATOM   421   C  CG  . HIS A 1 75  ? 169.408 195.234 186.593 1.00 33.00  ? 75  HIS A CG  1 
ATOM   422   N  ND1 . HIS A 1 75  ? 169.759 194.875 185.311 1.00 33.00  ? 75  HIS A ND1 1 
ATOM   423   C  CD2 . HIS A 1 75  ? 170.458 195.927 187.091 1.00 33.00  ? 75  HIS A CD2 1 
ATOM   424   C  CE1 . HIS A 1 75  ? 170.961 195.349 185.037 1.00 33.00  ? 75  HIS A CE1 1 
ATOM   425   N  NE2 . HIS A 1 75  ? 171.410 195.986 186.103 1.00 33.00  ? 75  HIS A NE2 1 
ATOM   426   N  N   . ARG A 1 76  ? 165.648 195.872 189.009 1.00 27.44  ? 76  ARG A N   1 
ATOM   427   C  CA  . ARG A 1 76  ? 164.298 195.652 189.512 1.00 27.44  ? 76  ARG A CA  1 
ATOM   428   C  C   . ARG A 1 76  ? 163.421 194.939 188.493 1.00 27.44  ? 76  ARG A C   1 
ATOM   429   O  O   . ARG A 1 76  ? 162.469 194.249 188.873 1.00 27.44  ? 76  ARG A O   1 
ATOM   430   C  CB  . ARG A 1 76  ? 163.657 196.979 189.911 1.00 27.44  ? 76  ARG A CB  1 
ATOM   431   C  CG  . ARG A 1 76  ? 164.334 197.670 191.073 1.00 27.44  ? 76  ARG A CG  1 
ATOM   432   C  CD  . ARG A 1 76  ? 163.575 198.918 191.490 1.00 27.44  ? 76  ARG A CD  1 
ATOM   433   N  NE  . ARG A 1 76  ? 163.611 199.961 190.473 1.00 27.44  ? 76  ARG A NE  1 
ATOM   434   C  CZ  . ARG A 1 76  ? 162.903 201.084 190.532 1.00 27.44  ? 76  ARG A CZ  1 
ATOM   435   N  NH1 . ARG A 1 76  ? 162.097 201.307 191.559 1.00 27.44  ? 76  ARG A NH1 1 
ATOM   436   N  NH2 . ARG A 1 76  ? 162.997 201.981 189.561 1.00 27.44  ? 76  ARG A NH2 1 
ATOM   437   N  N   . LEU A 1 77  ? 163.723 195.086 187.203 1.00 25.12  ? 77  LEU A N   1 
ATOM   438   C  CA  . LEU A 1 77  ? 162.854 194.531 186.172 1.00 25.12  ? 77  LEU A CA  1 
ATOM   439   C  C   . LEU A 1 77  ? 162.982 193.014 186.099 1.00 25.12  ? 77  LEU A C   1 
ATOM   440   O  O   . LEU A 1 77  ? 162.009 192.312 185.801 1.00 25.12  ? 77  LEU A O   1 
ATOM   441   C  CB  . LEU A 1 77  ? 163.177 195.169 184.822 1.00 25.12  ? 77  LEU A CB  1 
ATOM   442   C  CG  . LEU A 1 77  ? 162.296 194.759 183.644 1.00 25.12  ? 77  LEU A CG  1 
ATOM   443   C  CD1 . LEU A 1 77  ? 160.854 195.166 183.892 1.00 25.12  ? 77  LEU A CD1 1 
ATOM   444   C  CD2 . LEU A 1 77  ? 162.818 195.376 182.360 1.00 25.12  ? 77  LEU A CD2 1 
ATOM   445   N  N   . VAL A 1 78  ? 164.175 192.487 186.376 1.00 28.68  ? 78  VAL A N   1 
ATOM   446   C  CA  . VAL A 1 78  ? 164.370 191.043 186.312 1.00 28.68  ? 78  VAL A CA  1 
ATOM   447   C  C   . VAL A 1 78  ? 163.814 190.376 187.563 1.00 28.68  ? 78  VAL A C   1 
ATOM   448   O  O   . VAL A 1 78  ? 163.125 189.349 187.485 1.00 28.68  ? 78  VAL A O   1 
ATOM   449   C  CB  . VAL A 1 78  ? 165.859 190.716 186.115 1.00 28.68  ? 78  VAL A CB  1 
ATOM   450   C  CG1 . VAL A 1 78  ? 166.049 189.217 185.991 1.00 28.68  ? 78  VAL A CG1 1 
ATOM   451   C  CG2 . VAL A 1 78  ? 166.398 191.444 184.903 1.00 28.68  ? 78  VAL A CG2 1 
ATOM   452   N  N   . LEU A 1 79  ? 164.107 190.945 188.734 1.00 24.38  ? 79  LEU A N   1 
ATOM   453   C  CA  . LEU A 1 79  ? 163.542 190.431 189.975 1.00 24.38  ? 79  LEU A CA  1 
ATOM   454   C  C   . LEU A 1 79  ? 162.022 190.489 189.944 1.00 24.38  ? 79  LEU A C   1 
ATOM   455   O  O   . LEU A 1 79  ? 161.347 189.564 190.411 1.00 24.38  ? 79  LEU A O   1 
ATOM   456   C  CB  . LEU A 1 79  ? 164.083 191.227 191.160 1.00 24.38  ? 79  LEU A CB  1 
ATOM   457   C  CG  . LEU A 1 79  ? 165.596 191.173 191.365 1.00 24.38  ? 79  LEU A CG  1 
ATOM   458   C  CD1 . LEU A 1 79  ? 166.008 192.078 192.507 1.00 24.38  ? 79  LEU A CD1 1 
ATOM   459   C  CD2 . LEU A 1 79  ? 166.066 189.753 191.596 1.00 24.38  ? 79  LEU A CD2 1 
ATOM   460   N  N   . SER A 1 80  ? 161.464 191.567 189.392 1.00 25.34  ? 80  SER A N   1 
ATOM   461   C  CA  . SER A 1 80  ? 160.016 191.658 189.261 1.00 25.34  ? 80  SER A CA  1 
ATOM   462   C  C   . SER A 1 80  ? 159.490 190.714 188.190 1.00 25.34  ? 80  SER A C   1 
ATOM   463   O  O   . SER A 1 80  ? 158.337 190.277 188.264 1.00 25.34  ? 80  SER A O   1 
ATOM   464   C  CB  . SER A 1 80  ? 159.608 193.094 188.946 1.00 25.34  ? 80  SER A CB  1 
ATOM   465   O  OG  . SER A 1 80  ? 159.940 193.964 190.012 1.00 25.34  ? 80  SER A OG  1 
ATOM   466   N  N   . ALA A 1 81  ? 160.312 190.389 187.191 1.00 22.16  ? 81  ALA A N   1 
ATOM   467   C  CA  . ALA A 1 81  ? 159.864 189.486 186.138 1.00 22.16  ? 81  ALA A CA  1 
ATOM   468   C  C   . ALA A 1 81  ? 159.788 188.045 186.622 1.00 22.16  ? 81  ALA A C   1 
ATOM   469   O  O   . ALA A 1 81  ? 158.853 187.322 186.263 1.00 22.16  ? 81  ALA A O   1 
ATOM   470   C  CB  . ALA A 1 81  ? 160.790 189.590 184.927 1.00 22.16  ? 81  ALA A CB  1 
ATOM   471   N  N   . GLN A 1 82  ? 160.750 187.611 187.437 1.00 28.65  ? 82  GLN A N   1 
ATOM   472   C  CA  . GLN A 1 82  ? 160.795 186.223 187.886 1.00 28.65  ? 82  GLN A CA  1 
ATOM   473   C  C   . GLN A 1 82  ? 159.814 185.932 189.017 1.00 28.65  ? 82  GLN A C   1 
ATOM   474   O  O   . GLN A 1 82  ? 159.021 184.990 188.926 1.00 28.65  ? 82  GLN A O   1 
ATOM   475   C  CB  . GLN A 1 82  ? 162.215 185.860 188.326 1.00 28.65  ? 82  GLN A CB  1 
ATOM   476   C  CG  . GLN A 1 82  ? 163.201 185.769 187.183 1.00 28.65  ? 82  GLN A CG  1 
ATOM   477   C  CD  . GLN A 1 82  ? 162.864 184.647 186.231 1.00 28.65  ? 82  GLN A CD  1 
ATOM   478   O  OE1 . GLN A 1 82  ? 162.398 184.882 185.120 1.00 28.65  ? 82  GLN A OE1 1 
ATOM   479   N  NE2 . GLN A 1 82  ? 163.100 183.417 186.660 1.00 28.65  ? 82  GLN A NE2 1 
ATOM   480   N  N   . SER A 1 83  ? 159.857 186.720 190.085 1.00 24.28  ? 83  SER A N   1 
ATOM   481   C  CA  . SER A 1 83  ? 159.129 186.426 191.310 1.00 24.28  ? 83  SER A CA  1 
ATOM   482   C  C   . SER A 1 83  ? 157.957 187.382 191.470 1.00 24.28  ? 83  SER A C   1 
ATOM   483   O  O   . SER A 1 83  ? 157.788 188.306 190.669 1.00 24.28  ? 83  SER A O   1 
ATOM   484   C  CB  . SER A 1 83  ? 160.054 186.527 192.520 1.00 24.28  ? 83  SER A CB  1 
ATOM   485   O  OG  . SER A 1 83  ? 160.485 187.860 192.710 1.00 24.28  ? 83  SER A OG  1 
ATOM   486   N  N   . CYS A 1 84  ? 157.149 187.151 192.506 1.00 23.23  ? 84  CYS A N   1 
ATOM   487   C  CA  . CYS A 1 84  ? 156.075 188.081 192.835 1.00 23.23  ? 84  CYS A CA  1 
ATOM   488   C  C   . CYS A 1 84  ? 156.338 188.776 194.162 1.00 23.23  ? 84  CYS A C   1 
ATOM   489   O  O   . CYS A 1 84  ? 155.818 189.872 194.405 1.00 23.23  ? 84  CYS A O   1 
ATOM   490   C  CB  . CYS A 1 84  ? 154.737 187.347 192.874 1.00 23.23  ? 84  CYS A CB  1 
ATOM   491   S  SG  . CYS A 1 84  ? 154.226 186.657 191.290 1.00 23.23  ? 84  CYS A SG  1 
ATOM   492   N  N   . PHE A 1 85  ? 157.133 188.147 195.028 1.00 30.78  ? 85  PHE A N   1 
ATOM   493   C  CA  . PHE A 1 85  ? 157.555 188.782 196.270 1.00 30.78  ? 85  PHE A CA  1 
ATOM   494   C  C   . PHE A 1 85  ? 158.276 190.094 195.991 1.00 30.78  ? 85  PHE A C   1 
ATOM   495   O  O   . PHE A 1 85  ? 158.004 191.119 196.630 1.00 30.78  ? 85  PHE A O   1 
ATOM   496   C  CB  . PHE A 1 85  ? 158.451 187.818 197.045 1.00 30.78  ? 85  PHE A CB  1 
ATOM   497   C  CG  . PHE A 1 85  ? 158.923 188.343 198.363 1.00 30.78  ? 85  PHE A CG  1 
ATOM   498   C  CD1 . PHE A 1 85  ? 158.062 188.423 199.441 1.00 30.78  ? 85  PHE A CD1 1 
ATOM   499   C  CD2 . PHE A 1 85  ? 160.239 188.728 198.534 1.00 30.78  ? 85  PHE A CD2 1 
ATOM   500   C  CE1 . PHE A 1 85  ? 158.502 188.900 200.659 1.00 30.78  ? 85  PHE A CE1 1 
ATOM   501   C  CE2 . PHE A 1 85  ? 160.686 189.197 199.749 1.00 30.78  ? 85  PHE A CE2 1 
ATOM   502   C  CZ  . PHE A 1 85  ? 159.817 189.285 200.813 1.00 30.78  ? 85  PHE A CZ  1 
ATOM   503   N  N   . PHE A 1 86  ? 159.188 190.087 195.018 1.00 28.28  ? 86  PHE A N   1 
ATOM   504   C  CA  . PHE A 1 86  ? 159.915 191.308 194.694 1.00 28.28  ? 86  PHE A CA  1 
ATOM   505   C  C   . PHE A 1 86  ? 159.058 192.294 193.911 1.00 28.28  ? 86  PHE A C   1 
ATOM   506   O  O   . PHE A 1 86  ? 159.115 193.496 194.182 1.00 28.28  ? 86  PHE A O   1 
ATOM   507   C  CB  . PHE A 1 86  ? 161.193 190.982 193.924 1.00 28.28  ? 86  PHE A CB  1 
ATOM   508   C  CG  . PHE A 1 86  ? 162.262 190.334 194.763 1.00 28.28  ? 86  PHE A CG  1 
ATOM   509   C  CD1 . PHE A 1 86  ? 163.007 191.083 195.656 1.00 28.28  ? 86  PHE A CD1 1 
ATOM   510   C  CD2 . PHE A 1 86  ? 162.546 188.987 194.632 1.00 28.28  ? 86  PHE A CD2 1 
ATOM   511   C  CE1 . PHE A 1 86  ? 163.995 190.497 196.422 1.00 28.28  ? 86  PHE A CE1 1 
ATOM   512   C  CE2 . PHE A 1 86  ? 163.535 188.397 195.392 1.00 28.28  ? 86  PHE A CE2 1 
ATOM   513   C  CZ  . PHE A 1 86  ? 164.259 189.154 196.287 1.00 28.28  ? 86  PHE A CZ  1 
ATOM   514   N  N   . ARG A 1 87  ? 158.254 191.829 192.950 1.00 29.62  ? 87  ARG A N   1 
ATOM   515   C  CA  . ARG A 1 87  ? 157.424 192.774 192.205 1.00 29.62  ? 87  ARG A CA  1 
ATOM   516   C  C   . ARG A 1 87  ? 156.363 193.388 193.107 1.00 29.62  ? 87  ARG A C   1 
ATOM   517   O  O   . ARG A 1 87  ? 155.754 194.406 192.760 1.00 29.62  ? 87  ARG A O   1 
ATOM   518   C  CB  . ARG A 1 87  ? 156.761 192.107 191.000 1.00 29.62  ? 87  ARG A CB  1 
ATOM   519   C  CG  . ARG A 1 87  ? 155.577 191.233 191.348 1.00 29.62  ? 87  ARG A CG  1 
ATOM   520   C  CD  . ARG A 1 87  ? 154.942 190.612 190.111 1.00 29.62  ? 87  ARG A CD  1 
ATOM   521   N  NE  . ARG A 1 87  ? 155.793 189.611 189.477 1.00 29.62  ? 87  ARG A NE  1 
ATOM   522   C  CZ  . ARG A 1 87  ? 155.507 189.015 188.324 1.00 29.62  ? 87  ARG A CZ  1 
ATOM   523   N  NH1 . ARG A 1 87  ? 154.389 189.319 187.680 1.00 29.62  ? 87  ARG A NH1 1 
ATOM   524   N  NH2 . ARG A 1 87  ? 156.335 188.115 187.816 1.00 29.62  ? 87  ARG A NH2 1 
ATOM   525   N  N   . SER A 1 88  ? 156.119 192.774 194.267 1.00 27.10  ? 88  SER A N   1 
ATOM   526   C  CA  . SER A 1 88  ? 155.247 193.393 195.257 1.00 27.10  ? 88  SER A CA  1 
ATOM   527   C  C   . SER A 1 88  ? 156.044 194.213 196.263 1.00 27.10  ? 88  SER A C   1 
ATOM   528   O  O   . SER A 1 88  ? 155.478 195.071 196.948 1.00 27.10  ? 88  SER A O   1 
ATOM   529   C  CB  . SER A 1 88  ? 154.420 192.324 195.969 1.00 27.10  ? 88  SER A CB  1 
ATOM   530   O  OG  . SER A 1 88  ? 153.563 191.660 195.057 1.00 27.10  ? 88  SER A OG  1 
ATOM   531   N  N   . MET A 1 89  ? 157.354 193.972 196.363 1.00 31.92  ? 89  MET A N   1 
ATOM   532   C  CA  . MET A 1 89  ? 158.177 194.761 197.274 1.00 31.92  ? 89  MET A CA  1 
ATOM   533   C  C   . MET A 1 89  ? 158.574 196.100 196.662 1.00 31.92  ? 89  MET A C   1 
ATOM   534   O  O   . MET A 1 89  ? 158.565 197.126 197.350 1.00 31.92  ? 89  MET A O   1 
ATOM   535   C  CB  . MET A 1 89  ? 159.422 193.975 197.677 1.00 31.92  ? 89  MET A CB  1 
ATOM   536   C  CG  . MET A 1 89  ? 160.330 194.734 198.627 1.00 31.92  ? 89  MET A CG  1 
ATOM   537   S  SD  . MET A 1 89  ? 161.801 193.812 199.098 1.00 31.92  ? 89  MET A SD  1 
ATOM   538   C  CE  . MET A 1 89  ? 161.105 192.633 200.248 1.00 31.92  ? 89  MET A CE  1 
ATOM   539   N  N   . PHE A 1 90  ? 158.932 196.112 195.374 1.00 33.21  ? 90  PHE A N   1 
ATOM   540   C  CA  . PHE A 1 90  ? 159.457 197.334 194.771 1.00 33.21  ? 90  PHE A CA  1 
ATOM   541   C  C   . PHE A 1 90  ? 158.346 198.331 194.467 1.00 33.21  ? 90  PHE A C   1 
ATOM   542   O  O   . PHE A 1 90  ? 158.581 199.545 194.464 1.00 33.21  ? 90  PHE A O   1 
ATOM   543   C  CB  . PHE A 1 90  ? 160.239 197.011 193.498 1.00 33.21  ? 90  PHE A CB  1 
ATOM   544   C  CG  . PHE A 1 90  ? 161.488 196.214 193.735 1.00 33.21  ? 90  PHE A CG  1 
ATOM   545   C  CD1 . PHE A 1 90  ? 162.596 196.799 194.316 1.00 33.21  ? 90  PHE A CD1 1 
ATOM   546   C  CD2 . PHE A 1 90  ? 161.574 194.898 193.328 1.00 33.21  ? 90  PHE A CD2 1 
ATOM   547   C  CE1 . PHE A 1 90  ? 163.750 196.073 194.527 1.00 33.21  ? 90  PHE A CE1 1 
ATOM   548   C  CE2 . PHE A 1 90  ? 162.727 194.168 193.534 1.00 33.21  ? 90  PHE A CE2 1 
ATOM   549   C  CZ  . PHE A 1 90  ? 163.817 194.758 194.132 1.00 33.21  ? 90  PHE A CZ  1 
ATOM   550   N  N   . THR A 1 91  ? 157.135 197.845 194.204 1.00 38.93  ? 91  THR A N   1 
ATOM   551   C  CA  . THR A 1 91  ? 156.005 198.718 193.883 1.00 38.93  ? 91  THR A CA  1 
ATOM   552   C  C   . THR A 1 91  ? 155.128 198.934 195.117 1.00 38.93  ? 91  THR A C   1 
ATOM   553   O  O   . THR A 1 91  ? 153.983 198.490 195.197 1.00 38.93  ? 91  THR A O   1 
ATOM   554   C  CB  . THR A 1 91  ? 155.199 198.137 192.727 1.00 38.93  ? 91  THR A CB  1 
ATOM   555   O  OG1 . THR A 1 91  ? 154.638 196.879 193.119 1.00 38.93  ? 91  THR A OG1 1 
ATOM   556   C  CG2 . THR A 1 91  ? 156.089 197.926 191.514 1.00 38.93  ? 91  THR A CG2 1 
ATOM   557   N  N   . SER A 1 92  ? 155.699 199.634 196.098 1.00 59.10  ? 92  SER A N   1 
ATOM   558   C  CA  . SER A 1 92  ? 154.956 199.923 197.320 1.00 59.10  ? 92  SER A CA  1 
ATOM   559   C  C   . SER A 1 92  ? 154.780 201.423 197.516 1.00 59.10  ? 92  SER A C   1 
ATOM   560   O  O   . SER A 1 92  ? 155.298 201.994 198.483 1.00 59.10  ? 92  SER A O   1 
ATOM   561   C  CB  . SER A 1 92  ? 155.664 199.304 198.524 1.00 59.10  ? 92  SER A CB  1 
ATOM   562   O  OG  . SER A 1 92  ? 156.914 199.930 198.756 1.00 59.10  ? 92  SER A OG  1 
ATOM   563   N  N   . ASN A 1 93  ? 154.059 202.077 196.612 1.00 79.63  ? 93  ASN A N   1 
ATOM   564   C  CA  . ASN A 1 93  ? 153.837 203.514 196.698 1.00 79.63  ? 93  ASN A CA  1 
ATOM   565   C  C   . ASN A 1 93  ? 152.506 203.808 197.382 1.00 79.63  ? 93  ASN A C   1 
ATOM   566   O  O   . ASN A 1 93  ? 152.451 204.006 198.596 1.00 79.63  ? 93  ASN A O   1 
ATOM   567   C  CB  . ASN A 1 93  ? 153.873 204.145 195.303 1.00 79.63  ? 93  ASN A CB  1 
ATOM   568   C  CG  . ASN A 1 93  ? 153.906 205.662 195.346 1.00 79.63  ? 93  ASN A CG  1 
ATOM   569   O  OD1 . ASN A 1 93  ? 153.885 206.269 196.416 1.00 79.63  ? 93  ASN A OD1 1 
ATOM   570   N  ND2 . ASN A 1 93  ? 153.961 206.283 194.173 1.00 79.63  ? 93  ASN A ND2 1 
ATOM   571   N  N   . ASN A 1 99  ? 163.490 203.679 198.417 1.00 85.74  ? 99  ASN A N   1 
ATOM   572   C  CA  . ASN A 1 99  ? 164.531 204.441 197.738 1.00 85.74  ? 99  ASN A CA  1 
ATOM   573   C  C   . ASN A 1 99  ? 165.864 204.278 198.458 1.00 85.74  ? 99  ASN A C   1 
ATOM   574   O  O   . ASN A 1 99  ? 166.759 205.112 198.327 1.00 85.74  ? 99  ASN A O   1 
ATOM   575   C  CB  . ASN A 1 99  ? 164.150 205.919 197.656 1.00 85.74  ? 99  ASN A CB  1 
ATOM   576   C  CG  . ASN A 1 99  ? 162.975 206.168 196.730 1.00 85.74  ? 99  ASN A CG  1 
ATOM   577   O  OD1 . ASN A 1 99  ? 162.884 205.581 195.652 1.00 85.74  ? 99  ASN A OD1 1 
ATOM   578   N  ND2 . ASN A 1 99  ? 162.067 207.042 197.149 1.00 85.74  ? 99  ASN A ND2 1 
ATOM   579   N  N   . ARG A 1 100 ? 165.986 203.194 199.217 1.00 73.20  ? 100 ARG A N   1 
ATOM   580   C  CA  . ARG A 1 100 ? 167.167 202.948 200.027 1.00 73.20  ? 100 ARG A CA  1 
ATOM   581   C  C   . ARG A 1 100 ? 167.776 201.591 199.681 1.00 73.20  ? 100 ARG A C   1 
ATOM   582   O  O   . ARG A 1 100 ? 167.361 200.911 198.738 1.00 73.20  ? 100 ARG A O   1 
ATOM   583   C  CB  . ARG A 1 100 ? 166.815 203.021 201.512 1.00 73.20  ? 100 ARG A CB  1 
ATOM   584   C  CG  . ARG A 1 100 ? 166.062 201.800 202.042 1.00 73.20  ? 100 ARG A CG  1 
ATOM   585   C  CD  . ARG A 1 100 ? 164.576 201.853 201.715 1.00 73.20  ? 100 ARG A CD  1 
ATOM   586   N  NE  . ARG A 1 100 ? 163.825 200.798 202.388 1.00 73.20  ? 100 ARG A NE  1 
ATOM   587   C  CZ  . ARG A 1 100 ? 162.556 200.501 202.124 1.00 73.20  ? 100 ARG A CZ  1 
ATOM   588   N  NH1 . ARG A 1 100 ? 161.892 201.182 201.201 1.00 73.20  ? 100 ARG A NH1 1 
ATOM   589   N  NH2 . ARG A 1 100 ? 161.950 199.523 202.784 1.00 73.20  ? 100 ARG A NH2 1 
ATOM   590   N  N   . VAL A 1 101 ? 168.785 201.194 200.456 1.00 57.40  ? 101 VAL A N   1 
ATOM   591   C  CA  . VAL A 1 101 ? 169.322 199.844 200.354 1.00 57.40  ? 101 VAL A CA  1 
ATOM   592   C  C   . VAL A 1 101 ? 168.495 198.906 201.226 1.00 57.40  ? 101 VAL A C   1 
ATOM   593   O  O   . VAL A 1 101 ? 168.680 198.828 202.448 1.00 57.40  ? 101 VAL A O   1 
ATOM   594   C  CB  . VAL A 1 101 ? 170.817 199.830 200.718 1.00 57.40  ? 101 VAL A CB  1 
ATOM   595   C  CG1 . VAL A 1 101 ? 171.078 200.489 202.069 1.00 57.40  ? 101 VAL A CG1 1 
ATOM   596   C  CG2 . VAL A 1 101 ? 171.348 198.407 200.719 1.00 57.40  ? 101 VAL A CG2 1 
ATOM   597   N  N   . ILE A 1 102 ? 167.552 198.205 200.602 1.00 51.61  ? 102 ILE A N   1 
ATOM   598   C  CA  . ILE A 1 102 ? 166.665 197.281 201.298 1.00 51.61  ? 102 ILE A CA  1 
ATOM   599   C  C   . ILE A 1 102 ? 167.488 196.099 201.784 1.00 51.61  ? 102 ILE A C   1 
ATOM   600   O  O   . ILE A 1 102 ? 168.307 195.547 201.041 1.00 51.61  ? 102 ILE A O   1 
ATOM   601   C  CB  . ILE A 1 102 ? 165.492 196.827 200.405 1.00 51.61  ? 102 ILE A CB  1 
ATOM   602   C  CG1 . ILE A 1 102 ? 165.995 196.146 199.133 1.00 51.61  ? 102 ILE A CG1 1 
ATOM   603   C  CG2 . ILE A 1 102 ? 164.601 198.009 200.058 1.00 51.61  ? 102 ILE A CG2 1 
ATOM   604   C  CD1 . ILE A 1 102 ? 164.897 195.501 198.321 1.00 51.61  ? 102 ILE A CD1 1 
ATOM   605   N  N   . VAL A 1 103 ? 167.287 195.728 203.045 1.00 52.65  ? 103 VAL A N   1 
ATOM   606   C  CA  . VAL A 1 103 ? 168.055 194.669 203.687 1.00 52.65  ? 103 VAL A CA  1 
ATOM   607   C  C   . VAL A 1 103 ? 167.130 193.498 203.988 1.00 52.65  ? 103 VAL A C   1 
ATOM   608   O  O   . VAL A 1 103 ? 166.018 193.679 204.499 1.00 52.65  ? 103 VAL A O   1 
ATOM   609   C  CB  . VAL A 1 103 ? 168.763 195.176 204.962 1.00 52.65  ? 103 VAL A CB  1 
ATOM   610   C  CG1 . VAL A 1 103 ? 167.760 195.661 206.000 1.00 52.65  ? 103 VAL A CG1 1 
ATOM   611   C  CG2 . VAL A 1 103 ? 169.657 194.091 205.543 1.00 52.65  ? 103 VAL A CG2 1 
ATOM   612   N  N   . LEU A 1 104 ? 167.583 192.299 203.639 1.00 49.27  ? 104 LEU A N   1 
ATOM   613   C  CA  . LEU A 1 104 ? 166.851 191.070 203.906 1.00 49.27  ? 104 LEU A CA  1 
ATOM   614   C  C   . LEU A 1 104 ? 167.417 190.436 205.169 1.00 49.27  ? 104 LEU A C   1 
ATOM   615   O  O   . LEU A 1 104 ? 168.638 190.328 205.321 1.00 49.27  ? 104 LEU A O   1 
ATOM   616   C  CB  . LEU A 1 104 ? 166.952 190.117 202.715 1.00 49.27  ? 104 LEU A CB  1 
ATOM   617   C  CG  . LEU A 1 104 ? 166.293 190.671 201.449 1.00 49.27  ? 104 LEU A CG  1 
ATOM   618   C  CD1 . LEU A 1 104 ? 166.566 189.781 200.258 1.00 49.27  ? 104 LEU A CD1 1 
ATOM   619   C  CD2 . LEU A 1 104 ? 164.798 190.848 201.649 1.00 49.27  ? 104 LEU A CD2 1 
ATOM   620   N  N   . GLN A 1 105 ? 166.529 190.021 206.074 1.00 61.57  ? 105 GLN A N   1 
ATOM   621   C  CA  . GLN A 1 105 ? 166.946 189.763 207.448 1.00 61.57  ? 105 GLN A CA  1 
ATOM   622   C  C   . GLN A 1 105 ? 166.861 188.281 207.796 1.00 61.57  ? 105 GLN A C   1 
ATOM   623   O  O   . GLN A 1 105 ? 166.994 187.898 208.964 1.00 61.57  ? 105 GLN A O   1 
ATOM   624   C  CB  . GLN A 1 105 ? 166.091 190.592 208.407 1.00 61.57  ? 105 GLN A CB  1 
ATOM   625   C  CG  . GLN A 1 105 ? 164.649 190.115 208.521 1.00 61.57  ? 105 GLN A CG  1 
ATOM   626   C  CD  . GLN A 1 105 ? 163.760 190.645 207.411 1.00 61.57  ? 105 GLN A CD  1 
ATOM   627   O  OE1 . GLN A 1 105 ? 164.244 191.119 206.383 1.00 61.57  ? 105 GLN A OE1 1 
ATOM   628   N  NE2 . GLN A 1 105 ? 162.450 190.561 207.611 1.00 61.57  ? 105 GLN A NE2 1 
ATOM   629   N  N   . ASP A 1 106 ? 166.646 187.427 206.798 1.00 56.89  ? 106 ASP A N   1 
ATOM   630   C  CA  . ASP A 1 106 ? 166.528 186.002 207.085 1.00 56.89  ? 106 ASP A CA  1 
ATOM   631   C  C   . ASP A 1 106 ? 167.009 185.131 205.932 1.00 56.89  ? 106 ASP A C   1 
ATOM   632   O  O   . ASP A 1 106 ? 166.424 184.078 205.658 1.00 56.89  ? 106 ASP A O   1 
ATOM   633   C  CB  . ASP A 1 106 ? 165.082 185.659 207.451 1.00 56.89  ? 106 ASP A CB  1 
ATOM   634   C  CG  . ASP A 1 106 ? 164.096 186.037 206.364 1.00 56.89  ? 106 ASP A CG  1 
ATOM   635   O  OD1 . ASP A 1 106 ? 164.519 186.616 205.342 1.00 56.89  ? 106 ASP A OD1 1 
ATOM   636   O  OD2 . ASP A 1 106 ? 162.891 185.760 206.539 1.00 56.89  ? 106 ASP A OD2 1 
ATOM   637   N  N   . VAL A 1 107 ? 168.072 185.558 205.253 1.00 44.50  ? 107 VAL A N   1 
ATOM   638   C  CA  . VAL A 1 107 ? 168.718 184.740 204.232 1.00 44.50  ? 107 VAL A CA  1 
ATOM   639   C  C   . VAL A 1 107 ? 170.223 184.786 204.449 1.00 44.50  ? 107 VAL A C   1 
ATOM   640   O  O   . VAL A 1 107 ? 170.745 185.724 205.059 1.00 44.50  ? 107 VAL A O   1 
ATOM   641   C  CB  . VAL A 1 107 ? 168.351 185.199 202.809 1.00 44.50  ? 107 VAL A CB  1 
ATOM   642   C  CG1 . VAL A 1 107 ? 166.873 184.985 202.544 1.00 44.50  ? 107 VAL A CG1 1 
ATOM   643   C  CG2 . VAL A 1 107 ? 168.722 186.654 202.612 1.00 44.50  ? 107 VAL A CG2 1 
ATOM   644   N  N   . SER A 1 108 ? 170.926 183.771 203.957 1.00 43.27  ? 108 SER A N   1 
ATOM   645   C  CA  . SER A 1 108 ? 172.366 183.670 204.130 1.00 43.27  ? 108 SER A CA  1 
ATOM   646   C  C   . SER A 1 108 ? 173.039 184.390 202.972 1.00 43.27  ? 108 SER A C   1 
ATOM   647   O  O   . SER A 1 108 ? 172.460 184.545 201.894 1.00 43.27  ? 108 SER A O   1 
ATOM   648   C  CB  . SER A 1 108 ? 172.832 182.213 204.193 1.00 43.27  ? 108 SER A CB  1 
ATOM   649   O  OG  . SER A 1 108 ? 172.291 181.554 205.324 1.00 43.27  ? 108 SER A OG  1 
ATOM   650   N  N   . GLU A 1 109 ? 174.273 184.829 203.211 1.00 46.49  ? 109 GLU A N   1 
ATOM   651   C  CA  . GLU A 1 109 ? 175.064 185.461 202.164 1.00 46.49  ? 109 GLU A CA  1 
ATOM   652   C  C   . GLU A 1 109 ? 175.405 184.497 201.035 1.00 46.49  ? 109 GLU A C   1 
ATOM   653   O  O   . GLU A 1 109 ? 175.659 184.943 199.911 1.00 46.49  ? 109 GLU A O   1 
ATOM   654   C  CB  . GLU A 1 109 ? 176.346 186.042 202.767 1.00 46.49  ? 109 GLU A CB  1 
ATOM   655   C  CG  . GLU A 1 109 ? 177.213 186.837 201.803 1.00 46.49  ? 109 GLU A CG  1 
ATOM   656   C  CD  . GLU A 1 109 ? 178.448 187.409 202.471 1.00 46.49  ? 109 GLU A CD  1 
ATOM   657   O  OE1 . GLU A 1 109 ? 178.635 187.165 203.682 1.00 46.49  ? 109 GLU A OE1 1 
ATOM   658   O  OE2 . GLU A 1 109 ? 179.233 188.100 201.788 1.00 46.49  ? 109 GLU A OE2 1 
ATOM   659   N  N   . SER A 1 110 ? 175.402 183.192 201.303 1.00 39.36  ? 110 SER A N   1 
ATOM   660   C  CA  . SER A 1 110 ? 175.765 182.191 200.310 1.00 39.36  ? 110 SER A CA  1 
ATOM   661   C  C   . SER A 1 110 ? 174.576 181.471 199.698 1.00 39.36  ? 110 SER A C   1 
ATOM   662   O  O   . SER A 1 110 ? 174.774 180.589 198.863 1.00 39.36  ? 110 SER A O   1 
ATOM   663   C  CB  . SER A 1 110 ? 176.706 181.150 200.925 1.00 39.36  ? 110 SER A CB  1 
ATOM   664   O  OG  . SER A 1 110 ? 176.046 180.394 201.925 1.00 39.36  ? 110 SER A OG  1 
ATOM   665   N  N   . VAL A 1 111 ? 173.351 181.808 200.103 1.00 36.60  ? 111 VAL A N   1 
ATOM   666   C  CA  . VAL A 1 111 ? 172.176 181.221 199.465 1.00 36.60  ? 111 VAL A CA  1 
ATOM   667   C  C   . VAL A 1 111 ? 171.514 182.234 198.542 1.00 36.60  ? 111 VAL A C   1 
ATOM   668   O  O   . VAL A 1 111 ? 171.092 181.900 197.426 1.00 36.60  ? 111 VAL A O   1 
ATOM   669   C  CB  . VAL A 1 111 ? 171.199 180.691 200.527 1.00 36.60  ? 111 VAL A CB  1 
ATOM   670   C  CG1 . VAL A 1 111 ? 169.913 180.228 199.881 1.00 36.60  ? 111 VAL A CG1 1 
ATOM   671   C  CG2 . VAL A 1 111 ? 171.840 179.554 201.301 1.00 36.60  ? 111 VAL A CG2 1 
ATOM   672   N  N   . PHE A 1 112 ? 171.428 183.492 198.979 1.00 33.11  ? 112 PHE A N   1 
ATOM   673   C  CA  . PHE A 1 112 ? 170.898 184.524 198.100 1.00 33.11  ? 112 PHE A CA  1 
ATOM   674   C  C   . PHE A 1 112 ? 171.767 184.677 196.859 1.00 33.11  ? 112 PHE A C   1 
ATOM   675   O  O   . PHE A 1 112 ? 171.295 185.166 195.828 1.00 33.11  ? 112 PHE A O   1 
ATOM   676   C  CB  . PHE A 1 112 ? 170.795 185.849 198.849 1.00 33.11  ? 112 PHE A CB  1 
ATOM   677   C  CG  . PHE A 1 112 ? 169.970 186.880 198.139 1.00 33.11  ? 112 PHE A CG  1 
ATOM   678   C  CD1 . PHE A 1 112 ? 168.594 186.846 198.197 1.00 33.11  ? 112 PHE A CD1 1 
ATOM   679   C  CD2 . PHE A 1 112 ? 170.565 187.872 197.394 1.00 33.11  ? 112 PHE A CD2 1 
ATOM   680   C  CE1 . PHE A 1 112 ? 167.832 187.794 197.535 1.00 33.11  ? 112 PHE A CE1 1 
ATOM   681   C  CE2 . PHE A 1 112 ? 169.801 188.817 196.734 1.00 33.11  ? 112 PHE A CE2 1 
ATOM   682   C  CZ  . PHE A 1 112 ? 168.439 188.777 196.808 1.00 33.11  ? 112 PHE A CZ  1 
ATOM   683   N  N   . GLN A 1 113 ? 173.033 184.264 196.941 1.00 33.61  ? 113 GLN A N   1 
ATOM   684   C  CA  . GLN A 1 113 ? 173.886 184.241 195.759 1.00 33.61  ? 113 GLN A CA  1 
ATOM   685   C  C   . GLN A 1 113 ? 173.411 183.196 194.760 1.00 33.61  ? 113 GLN A C   1 
ATOM   686   O  O   . GLN A 1 113 ? 173.419 183.438 193.547 1.00 33.61  ? 113 GLN A O   1 
ATOM   687   C  CB  . GLN A 1 113 ? 175.333 183.978 196.167 1.00 33.61  ? 113 GLN A CB  1 
ATOM   688   C  CG  . GLN A 1 113 ? 176.306 183.982 195.011 1.00 33.61  ? 113 GLN A CG  1 
ATOM   689   C  CD  . GLN A 1 113 ? 176.328 185.310 194.288 1.00 33.61  ? 113 GLN A CD  1 
ATOM   690   O  OE1 . GLN A 1 113 ? 175.772 185.442 193.199 1.00 33.61  ? 113 GLN A OE1 1 
ATOM   691   N  NE2 . GLN A 1 113 ? 176.963 186.307 194.895 1.00 33.61  ? 113 GLN A NE2 1 
ATOM   692   N  N   . LEU A 1 114 ? 173.004 182.020 195.248 1.00 33.01  ? 114 LEU A N   1 
ATOM   693   C  CA  . LEU A 1 114 ? 172.378 181.036 194.371 1.00 33.01  ? 114 LEU A CA  1 
ATOM   694   C  C   . LEU A 1 114 ? 171.061 181.557 193.819 1.00 33.01  ? 114 LEU A C   1 
ATOM   695   O  O   . LEU A 1 114 ? 170.689 181.247 192.681 1.00 33.01  ? 114 LEU A O   1 
ATOM   696   C  CB  . LEU A 1 114 ? 172.156 179.717 195.111 1.00 33.01  ? 114 LEU A CB  1 
ATOM   697   C  CG  . LEU A 1 114 ? 173.309 178.714 195.175 1.00 33.01  ? 114 LEU A CG  1 
ATOM   698   C  CD1 . LEU A 1 114 ? 174.432 179.203 196.068 1.00 33.01  ? 114 LEU A CD1 1 
ATOM   699   C  CD2 . LEU A 1 114 ? 172.799 177.367 195.657 1.00 33.01  ? 114 LEU A CD2 1 
ATOM   700   N  N   . LEU A 1 115 ? 170.341 182.357 194.608 1.00 34.13  ? 115 LEU A N   1 
ATOM   701   C  CA  . LEU A 1 115 ? 169.078 182.902 194.124 1.00 34.13  ? 115 LEU A CA  1 
ATOM   702   C  C   . LEU A 1 115 ? 169.302 183.927 193.021 1.00 34.13  ? 115 LEU A C   1 
ATOM   703   O  O   . LEU A 1 115 ? 168.522 184.000 192.066 1.00 34.13  ? 115 LEU A O   1 
ATOM   704   C  CB  . LEU A 1 115 ? 168.297 183.516 195.279 1.00 34.13  ? 115 LEU A CB  1 
ATOM   705   C  CG  . LEU A 1 115 ? 167.893 182.508 196.350 1.00 34.13  ? 115 LEU A CG  1 
ATOM   706   C  CD1 . LEU A 1 115 ? 167.244 183.230 197.494 1.00 34.13  ? 115 LEU A CD1 1 
ATOM   707   C  CD2 . LEU A 1 115 ? 166.967 181.458 195.777 1.00 34.13  ? 115 LEU A CD2 1 
ATOM   708   N  N   . VAL A 1 116 ? 170.361 184.730 193.130 1.00 32.40  ? 116 VAL A N   1 
ATOM   709   C  CA  . VAL A 1 116 ? 170.675 185.680 192.065 1.00 32.40  ? 116 VAL A CA  1 
ATOM   710   C  C   . VAL A 1 116 ? 171.176 184.946 190.830 1.00 32.40  ? 116 VAL A C   1 
ATOM   711   O  O   . VAL A 1 116 ? 170.763 185.240 189.701 1.00 32.40  ? 116 VAL A O   1 
ATOM   712   C  CB  . VAL A 1 116 ? 171.696 186.720 192.558 1.00 32.40  ? 116 VAL A CB  1 
ATOM   713   C  CG1 . VAL A 1 116 ? 172.160 187.588 191.407 1.00 32.40  ? 116 VAL A CG1 1 
ATOM   714   C  CG2 . VAL A 1 116 ? 171.080 187.574 193.641 1.00 32.40  ? 116 VAL A CG2 1 
ATOM   715   N  N   . ASP A 1 117 ? 172.060 183.966 191.025 1.00 37.23  ? 117 ASP A N   1 
ATOM   716   C  CA  . ASP A 1 117 ? 172.581 183.207 189.893 1.00 37.23  ? 117 ASP A CA  1 
ATOM   717   C  C   . ASP A 1 117 ? 171.494 182.356 189.253 1.00 37.23  ? 117 ASP A C   1 
ATOM   718   O  O   . ASP A 1 117 ? 171.678 181.827 188.152 1.00 37.23  ? 117 ASP A O   1 
ATOM   719   C  CB  . ASP A 1 117 ? 173.751 182.341 190.346 1.00 37.23  ? 117 ASP A CB  1 
ATOM   720   C  CG  . ASP A 1 117 ? 174.963 183.162 190.732 1.00 37.23  ? 117 ASP A CG  1 
ATOM   721   O  OD1 . ASP A 1 117 ? 175.145 184.259 190.166 1.00 37.23  ? 117 ASP A OD1 1 
ATOM   722   O  OD2 . ASP A 1 117 ? 175.733 182.711 191.605 1.00 37.23  ? 117 ASP A OD2 1 
ATOM   723   N  N   . TYR A 1 118 ? 170.358 182.200 189.933 1.00 48.92  ? 118 TYR A N   1 
ATOM   724   C  CA  . TYR A 1 118 ? 169.219 181.540 189.307 1.00 48.92  ? 118 TYR A CA  1 
ATOM   725   C  C   . TYR A 1 118 ? 168.312 182.540 188.603 1.00 48.92  ? 118 TYR A C   1 
ATOM   726   O  O   . TYR A 1 118 ? 167.817 182.270 187.505 1.00 48.92  ? 118 TYR A O   1 
ATOM   727   C  CB  . TYR A 1 118 ? 168.423 180.752 190.342 1.00 48.92  ? 118 TYR A CB  1 
ATOM   728   C  CG  . TYR A 1 118 ? 167.189 180.116 189.757 1.00 48.92  ? 118 TYR A CG  1 
ATOM   729   C  CD1 . TYR A 1 118 ? 167.279 178.994 188.952 1.00 48.92  ? 118 TYR A CD1 1 
ATOM   730   C  CD2 . TYR A 1 118 ? 165.935 180.650 189.994 1.00 48.92  ? 118 TYR A CD2 1 
ATOM   731   C  CE1 . TYR A 1 118 ? 166.154 178.416 188.409 1.00 48.92  ? 118 TYR A CE1 1 
ATOM   732   C  CE2 . TYR A 1 118 ? 164.806 180.078 189.456 1.00 48.92  ? 118 TYR A CE2 1 
ATOM   733   C  CZ  . TYR A 1 118 ? 164.921 178.963 188.666 1.00 48.92  ? 118 TYR A CZ  1 
ATOM   734   O  OH  . TYR A 1 118 ? 163.796 178.391 188.128 1.00 48.92  ? 118 TYR A OH  1 
ATOM   735   N  N   . ILE A 1 119 ? 168.072 183.696 189.223 1.00 48.92  ? 119 ILE A N   1 
ATOM   736   C  CA  . ILE A 1 119 ? 167.170 184.679 188.630 1.00 48.92  ? 119 ILE A CA  1 
ATOM   737   C  C   . ILE A 1 119 ? 167.764 185.251 187.350 1.00 48.92  ? 119 ILE A C   1 
ATOM   738   O  O   . ILE A 1 119 ? 167.042 185.531 186.385 1.00 48.92  ? 119 ILE A O   1 
ATOM   739   C  CB  . ILE A 1 119 ? 166.833 185.779 189.654 1.00 48.92  ? 119 ILE A CB  1 
ATOM   740   C  CG1 . ILE A 1 119 ? 165.977 185.205 190.782 1.00 48.92  ? 119 ILE A CG1 1 
ATOM   741   C  CG2 . ILE A 1 119 ? 166.115 186.932 188.993 1.00 48.92  ? 119 ILE A CG2 1 
ATOM   742   C  CD1 . ILE A 1 119 ? 165.826 186.126 191.966 1.00 48.92  ? 119 ILE A CD1 1 
ATOM   743   N  N   . TYR A 1 120 ? 169.086 185.413 187.305 1.00 39.73  ? 120 TYR A N   1 
ATOM   744   C  CA  . TYR A 1 120 ? 169.725 185.954 186.108 1.00 39.73  ? 120 TYR A CA  1 
ATOM   745   C  C   . TYR A 1 120 ? 170.096 184.862 185.108 1.00 39.73  ? 120 TYR A C   1 
ATOM   746   O  O   . TYR A 1 120 ? 169.685 184.912 183.946 1.00 39.73  ? 120 TYR A O   1 
ATOM   747   C  CB  . TYR A 1 120 ? 170.962 186.772 186.491 1.00 39.73  ? 120 TYR A CB  1 
ATOM   748   C  CG  . TYR A 1 120 ? 170.638 188.087 187.155 1.00 39.73  ? 120 TYR A CG  1 
ATOM   749   C  CD1 . TYR A 1 120 ? 169.354 188.597 187.132 1.00 39.73  ? 120 TYR A CD1 1 
ATOM   750   C  CD2 . TYR A 1 120 ? 171.618 188.827 187.791 1.00 39.73  ? 120 TYR A CD2 1 
ATOM   751   C  CE1 . TYR A 1 120 ? 169.050 189.798 187.733 1.00 39.73  ? 120 TYR A CE1 1 
ATOM   752   C  CE2 . TYR A 1 120 ? 171.320 190.033 188.395 1.00 39.73  ? 120 TYR A CE2 1 
ATOM   753   C  CZ  . TYR A 1 120 ? 170.034 190.512 188.360 1.00 39.73  ? 120 TYR A CZ  1 
ATOM   754   O  OH  . TYR A 1 120 ? 169.723 191.709 188.956 1.00 39.73  ? 120 TYR A OH  1 
ATOM   755   N  N   . HIS A 1 121 ? 170.871 183.868 185.547 1.00 32.91  ? 121 HIS A N   1 
ATOM   756   C  CA  . HIS A 1 121 ? 171.377 182.862 184.620 1.00 32.91  ? 121 HIS A CA  1 
ATOM   757   C  C   . HIS A 1 121 ? 170.407 181.705 184.422 1.00 32.91  ? 121 HIS A C   1 
ATOM   758   O  O   . HIS A 1 121 ? 170.352 181.135 183.328 1.00 32.91  ? 121 HIS A O   1 
ATOM   759   C  CB  . HIS A 1 121 ? 172.722 182.325 185.106 1.00 32.91  ? 121 HIS A CB  1 
ATOM   760   C  CG  . HIS A 1 121 ? 173.830 183.328 185.053 1.00 32.91  ? 121 HIS A CG  1 
ATOM   761   N  ND1 . HIS A 1 121 ? 175.069 183.096 185.609 1.00 32.91  ? 121 HIS A ND1 1 
ATOM   762   C  CD2 . HIS A 1 121 ? 173.887 184.569 184.515 1.00 32.91  ? 121 HIS A CD2 1 
ATOM   763   C  CE1 . HIS A 1 121 ? 175.843 184.149 185.412 1.00 32.91  ? 121 HIS A CE1 1 
ATOM   764   N  NE2 . HIS A 1 121 ? 175.149 185.056 184.749 1.00 32.91  ? 121 HIS A NE2 1 
ATOM   765   N  N   . GLY A 1 122 ? 169.647 181.337 185.448 1.00 31.51  ? 122 GLY A N   1 
ATOM   766   C  CA  . GLY A 1 122 ? 168.734 180.220 185.341 1.00 31.51  ? 122 GLY A CA  1 
ATOM   767   C  C   . GLY A 1 122 ? 169.375 178.857 185.425 1.00 31.51  ? 122 GLY A C   1 
ATOM   768   O  O   . GLY A 1 122 ? 168.806 177.892 184.903 1.00 31.51  ? 122 GLY A O   1 
ATOM   769   N  N   . THR A 1 123 ? 170.540 178.746 186.058 1.00 32.66  ? 123 THR A N   1 
ATOM   770   C  CA  . THR A 1 123 ? 171.263 177.487 186.192 1.00 32.66  ? 123 THR A CA  1 
ATOM   771   C  C   . THR A 1 123 ? 171.988 177.499 187.527 1.00 32.66  ? 123 THR A C   1 
ATOM   772   O  O   . THR A 1 123 ? 173.065 178.090 187.644 1.00 32.66  ? 123 THR A O   1 
ATOM   773   C  CB  . THR A 1 123 ? 172.255 177.290 185.042 1.00 32.66  ? 123 THR A CB  1 
ATOM   774   O  OG1 . THR A 1 123 ? 171.551 177.286 183.794 1.00 32.66  ? 123 THR A OG1 1 
ATOM   775   C  CG2 . THR A 1 123 ? 172.990 175.978 185.194 1.00 32.66  ? 123 THR A CG2 1 
ATOM   776   N  N   . VAL A 1 124 ? 171.398 176.850 188.528 1.00 31.82  ? 124 VAL A N   1 
ATOM   777   C  CA  . VAL A 1 124 ? 171.881 176.896 189.902 1.00 31.82  ? 124 VAL A CA  1 
ATOM   778   C  C   . VAL A 1 124 ? 172.558 175.573 190.236 1.00 31.82  ? 124 VAL A C   1 
ATOM   779   O  O   . VAL A 1 124 ? 172.176 174.519 189.717 1.00 31.82  ? 124 VAL A O   1 
ATOM   780   C  CB  . VAL A 1 124 ? 170.728 177.203 190.883 1.00 31.82  ? 124 VAL A CB  1 
ATOM   781   C  CG1 . VAL A 1 124 ? 169.694 176.099 190.860 1.00 31.82  ? 124 VAL A CG1 1 
ATOM   782   C  CG2 . VAL A 1 124 ? 171.253 177.418 192.291 1.00 31.82  ? 124 VAL A CG2 1 
ATOM   783   N  N   . LYS A 1 125 ? 173.579 175.637 191.091 1.00 36.29  ? 125 LYS A N   1 
ATOM   784   C  CA  . LYS A 1 125 ? 174.339 174.464 191.522 1.00 36.29  ? 125 LYS A CA  1 
ATOM   785   C  C   . LYS A 1 125 ? 173.778 173.990 192.856 1.00 36.29  ? 125 LYS A C   1 
ATOM   786   O  O   . LYS A 1 125 ? 174.127 174.520 193.913 1.00 36.29  ? 125 LYS A O   1 
ATOM   787   C  CB  . LYS A 1 125 ? 175.821 174.801 191.637 1.00 36.29  ? 125 LYS A CB  1 
ATOM   788   C  CG  . LYS A 1 125 ? 176.702 173.641 192.064 1.00 36.29  ? 125 LYS A CG  1 
ATOM   789   C  CD  . LYS A 1 125 ? 176.847 172.616 190.954 1.00 36.29  ? 125 LYS A CD  1 
ATOM   790   C  CE  . LYS A 1 125 ? 177.831 171.526 191.341 1.00 36.29  ? 125 LYS A CE  1 
ATOM   791   N  NZ  . LYS A 1 125 ? 177.931 170.465 190.301 1.00 36.29  ? 125 LYS A NZ  1 
ATOM   792   N  N   . LEU A 1 126 ? 172.907 172.986 192.811 1.00 48.92  ? 126 LEU A N   1 
ATOM   793   C  CA  . LEU A 1 126 ? 172.289 172.471 194.025 1.00 48.92  ? 126 LEU A CA  1 
ATOM   794   C  C   . LEU A 1 126 ? 173.304 171.717 194.873 1.00 48.92  ? 126 LEU A C   1 
ATOM   795   O  O   . LEU A 1 126 ? 174.392 171.364 194.414 1.00 48.92  ? 126 LEU A O   1 
ATOM   796   C  CB  . LEU A 1 126 ? 171.120 171.556 193.679 1.00 48.92  ? 126 LEU A CB  1 
ATOM   797   C  CG  . LEU A 1 126 ? 169.924 172.237 193.021 1.00 48.92  ? 126 LEU A CG  1 
ATOM   798   C  CD1 . LEU A 1 126 ? 168.949 171.192 192.570 1.00 48.92  ? 126 LEU A CD1 1 
ATOM   799   C  CD2 . LEU A 1 126 ? 169.263 173.209 193.983 1.00 48.92  ? 126 LEU A CD2 1 
ATOM   800   N  N   . ARG A 1 127 ? 172.932 171.465 196.126 1.00 38.96  ? 127 ARG A N   1 
ATOM   801   C  CA  . ARG A 1 127 ? 173.819 170.799 197.065 1.00 38.96  ? 127 ARG A CA  1 
ATOM   802   C  C   . ARG A 1 127 ? 173.006 170.361 198.273 1.00 38.96  ? 127 ARG A C   1 
ATOM   803   O  O   . ARG A 1 127 ? 172.079 171.054 198.699 1.00 38.96  ? 127 ARG A O   1 
ATOM   804   C  CB  . ARG A 1 127 ? 174.970 171.719 197.480 1.00 38.96  ? 127 ARG A CB  1 
ATOM   805   C  CG  . ARG A 1 127 ? 176.089 171.036 198.230 1.00 38.96  ? 127 ARG A CG  1 
ATOM   806   C  CD  . ARG A 1 127 ? 177.224 172.010 198.464 1.00 38.96  ? 127 ARG A CD  1 
ATOM   807   N  NE  . ARG A 1 127 ? 177.742 172.521 197.198 1.00 38.96  ? 127 ARG A NE  1 
ATOM   808   C  CZ  . ARG A 1 127 ? 178.624 171.884 196.435 1.00 38.96  ? 127 ARG A CZ  1 
ATOM   809   N  NH1 . ARG A 1 127 ? 179.094 170.701 196.806 1.00 38.96  ? 127 ARG A NH1 1 
ATOM   810   N  NH2 . ARG A 1 127 ? 179.034 172.430 195.298 1.00 38.96  ? 127 ARG A NH2 1 
ATOM   811   N  N   . ALA A 1 128 ? 173.366 169.201 198.825 1.00 28.08  ? 128 ALA A N   1 
ATOM   812   C  CA  . ALA A 1 128 ? 172.540 168.591 199.861 1.00 28.08  ? 128 ALA A CA  1 
ATOM   813   C  C   . ALA A 1 128 ? 172.666 169.305 201.199 1.00 28.08  ? 128 ALA A C   1 
ATOM   814   O  O   . ALA A 1 128 ? 171.781 169.172 202.051 1.00 28.08  ? 128 ALA A O   1 
ATOM   815   C  CB  . ALA A 1 128 ? 172.903 167.116 200.018 1.00 28.08  ? 128 ALA A CB  1 
ATOM   816   N  N   . GLU A 1 129 ? 173.747 170.055 201.414 1.00 37.20  ? 129 GLU A N   1 
ATOM   817   C  CA  . GLU A 1 129 ? 173.931 170.725 202.696 1.00 37.20  ? 129 GLU A CA  1 
ATOM   818   C  C   . GLU A 1 129 ? 173.121 172.009 202.814 1.00 37.20  ? 129 GLU A C   1 
ATOM   819   O  O   . GLU A 1 129 ? 172.591 172.293 203.893 1.00 37.20  ? 129 GLU A O   1 
ATOM   820   C  CB  . GLU A 1 129 ? 175.415 171.021 202.933 1.00 37.20  ? 129 GLU A CB  1 
ATOM   821   C  CG  . GLU A 1 129 ? 176.036 171.995 201.947 1.00 37.20  ? 129 GLU A CG  1 
ATOM   822   C  CD  . GLU A 1 129 ? 177.513 172.222 202.198 1.00 37.20  ? 129 GLU A CD  1 
ATOM   823   O  OE1 . GLU A 1 129 ? 178.065 171.596 203.127 1.00 37.20  ? 129 GLU A OE1 1 
ATOM   824   O  OE2 . GLU A 1 129 ? 178.123 173.031 201.468 1.00 37.20  ? 129 GLU A OE2 1 
ATOM   825   N  N   . GLU A 1 130 ? 173.008 172.782 201.742 1.00 32.44  ? 130 GLU A N   1 
ATOM   826   C  CA  . GLU A 1 130 ? 172.249 174.024 201.734 1.00 32.44  ? 130 GLU A CA  1 
ATOM   827   C  C   . GLU A 1 130 ? 171.009 173.877 200.865 1.00 32.44  ? 130 GLU A C   1 
ATOM   828   O  O   . GLU A 1 130 ? 170.592 174.801 200.166 1.00 32.44  ? 130 GLU A O   1 
ATOM   829   C  CB  . GLU A 1 130 ? 173.127 175.189 201.284 1.00 32.44  ? 130 GLU A CB  1 
ATOM   830   C  CG  . GLU A 1 130 ? 173.702 175.053 199.889 1.00 32.44  ? 130 GLU A CG  1 
ATOM   831   C  CD  . GLU A 1 130 ? 174.732 176.121 199.585 1.00 32.44  ? 130 GLU A CD  1 
ATOM   832   O  OE1 . GLU A 1 130 ? 175.016 176.943 200.481 1.00 32.44  ? 130 GLU A OE1 1 
ATOM   833   O  OE2 . GLU A 1 130 ? 175.264 176.135 198.456 1.00 32.44  ? 130 GLU A OE2 1 
ATOM   834   N  N   . LEU A 1 131 ? 170.405 172.693 200.919 1.00 25.79  ? 131 LEU A N   1 
ATOM   835   C  CA  . LEU A 1 131 ? 169.174 172.380 200.209 1.00 25.79  ? 131 LEU A CA  1 
ATOM   836   C  C   . LEU A 1 131 ? 167.925 172.806 200.960 1.00 25.79  ? 131 LEU A C   1 
ATOM   837   O  O   . LEU A 1 131 ? 167.139 173.601 200.439 1.00 25.79  ? 131 LEU A O   1 
ATOM   838   C  CB  . LEU A 1 131 ? 169.091 170.881 199.943 1.00 25.79  ? 131 LEU A CB  1 
ATOM   839   C  CG  . LEU A 1 131 ? 167.796 170.506 199.244 1.00 25.79  ? 131 LEU A CG  1 
ATOM   840   C  CD1 . LEU A 1 131 ? 167.768 171.124 197.864 1.00 25.79  ? 131 LEU A CD1 1 
ATOM   841   C  CD2 . LEU A 1 131 ? 167.652 169.006 199.199 1.00 25.79  ? 131 LEU A CD2 1 
ATOM   842   N  N   . GLN A 1 132 ? 167.723 172.276 202.168 1.00 26.45  ? 132 GLN A N   1 
ATOM   843   C  CA  . GLN A 1 132 ? 166.543 172.617 202.955 1.00 26.45  ? 132 GLN A CA  1 
ATOM   844   C  C   . GLN A 1 132 ? 166.386 174.123 203.101 1.00 26.45  ? 132 GLN A C   1 
ATOM   845   O  O   . GLN A 1 132 ? 165.273 174.647 202.973 1.00 26.45  ? 132 GLN A O   1 
ATOM   846   C  CB  . GLN A 1 132 ? 166.630 171.949 204.324 1.00 26.45  ? 132 GLN A CB  1 
ATOM   847   C  CG  . GLN A 1 132 ? 165.452 172.217 205.225 1.00 26.45  ? 132 GLN A CG  1 
ATOM   848   C  CD  . GLN A 1 132 ? 165.558 171.471 206.533 1.00 26.45  ? 132 GLN A CD  1 
ATOM   849   O  OE1 . GLN A 1 132 ? 166.513 170.731 206.763 1.00 26.45  ? 132 GLN A OE1 1 
ATOM   850   N  NE2 . GLN A 1 132 ? 164.586 171.676 207.410 1.00 26.45  ? 132 GLN A NE2 1 
ATOM   851   N  N   . GLU A 1 133 ? 167.489 174.833 203.359 1.00 21.99  ? 133 GLU A N   1 
ATOM   852   C  CA  . GLU A 1 133 ? 167.449 176.292 203.418 1.00 21.99  ? 133 GLU A CA  1 
ATOM   853   C  C   . GLU A 1 133 ? 166.767 176.876 202.190 1.00 21.99  ? 133 GLU A C   1 
ATOM   854   O  O   . GLU A 1 133 ? 165.831 177.675 202.312 1.00 21.99  ? 133 GLU A O   1 
ATOM   855   C  CB  . GLU A 1 133 ? 168.865 176.848 203.557 1.00 21.99  ? 133 GLU A CB  1 
ATOM   856   C  CG  . GLU A 1 133 ? 168.947 178.367 203.594 1.00 21.99  ? 133 GLU A CG  1 
ATOM   857   C  CD  . GLU A 1 133 ? 168.325 178.964 204.839 1.00 21.99  ? 133 GLU A CD  1 
ATOM   858   O  OE1 . GLU A 1 133 ? 168.286 178.271 205.875 1.00 21.99  ? 133 GLU A OE1 1 
ATOM   859   O  OE2 . GLU A 1 133 ? 167.878 180.129 204.782 1.00 21.99  ? 133 GLU A OE2 1 
ATOM   860   N  N   . ILE A 1 134 ? 167.204 176.467 200.997 1.00 23.03  ? 134 ILE A N   1 
ATOM   861   C  CA  . ILE A 1 134 ? 166.576 176.953 199.772 1.00 23.03  ? 134 ILE A CA  1 
ATOM   862   C  C   . ILE A 1 134 ? 165.092 176.621 199.767 1.00 23.03  ? 134 ILE A C   1 
ATOM   863   O  O   . ILE A 1 134 ? 164.258 177.464 199.415 1.00 23.03  ? 134 ILE A O   1 
ATOM   864   C  CB  . ILE A 1 134 ? 167.290 176.379 198.536 1.00 23.03  ? 134 ILE A CB  1 
ATOM   865   C  CG1 . ILE A 1 134 ? 168.705 176.937 198.431 1.00 23.03  ? 134 ILE A CG1 1 
ATOM   866   C  CG2 . ILE A 1 134 ? 166.510 176.686 197.281 1.00 23.03  ? 134 ILE A CG2 1 
ATOM   867   C  CD1 . ILE A 1 134 ? 169.542 176.260 197.375 1.00 23.03  ? 134 ILE A CD1 1 
ATOM   868   N  N   . TYR A 1 135 ? 164.734 175.406 200.192 1.00 22.85  ? 135 TYR A N   1 
ATOM   869   C  CA  . TYR A 1 135 ? 163.328 175.013 200.218 1.00 22.85  ? 135 TYR A CA  1 
ATOM   870   C  C   . TYR A 1 135 ? 162.501 176.019 201.004 1.00 22.85  ? 135 TYR A C   1 
ATOM   871   O  O   . TYR A 1 135 ? 161.333 176.271 200.686 1.00 22.85  ? 135 TYR A O   1 
ATOM   872   C  CB  . TYR A 1 135 ? 163.186 173.614 200.813 1.00 22.85  ? 135 TYR A CB  1 
ATOM   873   C  CG  . TYR A 1 135 ? 161.781 173.067 200.769 1.00 22.85  ? 135 TYR A CG  1 
ATOM   874   C  CD1 . TYR A 1 135 ? 161.251 172.563 199.595 1.00 22.85  ? 135 TYR A CD1 1 
ATOM   875   C  CD2 . TYR A 1 135 ? 160.984 173.055 201.899 1.00 22.85  ? 135 TYR A CD2 1 
ATOM   876   C  CE1 . TYR A 1 135 ? 159.968 172.061 199.549 1.00 22.85  ? 135 TYR A CE1 1 
ATOM   877   C  CE2 . TYR A 1 135 ? 159.699 172.555 201.859 1.00 22.85  ? 135 TYR A CE2 1 
ATOM   878   C  CZ  . TYR A 1 135 ? 159.198 172.061 200.682 1.00 22.85  ? 135 TYR A CZ  1 
ATOM   879   O  OH  . TYR A 1 135 ? 157.919 171.562 200.640 1.00 22.85  ? 135 TYR A OH  1 
ATOM   880   N  N   . GLU A 1 136 ? 163.100 176.616 202.035 1.00 22.83  ? 136 GLU A N   1 
ATOM   881   C  CA  . GLU A 1 136 ? 162.453 177.725 202.722 1.00 22.83  ? 136 GLU A CA  1 
ATOM   882   C  C   . GLU A 1 136 ? 162.388 178.949 201.820 1.00 22.83  ? 136 GLU A C   1 
ATOM   883   O  O   . GLU A 1 136 ? 161.302 179.403 201.440 1.00 22.83  ? 136 GLU A O   1 
ATOM   884   C  CB  . GLU A 1 136 ? 163.211 178.054 204.007 1.00 22.83  ? 136 GLU A CB  1 
ATOM   885   C  CG  . GLU A 1 136 ? 163.198 176.965 205.065 1.00 22.83  ? 136 GLU A CG  1 
ATOM   886   C  CD  . GLU A 1 136 ? 161.835 176.774 205.691 1.00 22.83  ? 136 GLU A CD  1 
ATOM   887   O  OE1 . GLU A 1 136 ? 161.063 177.752 205.756 1.00 22.83  ? 136 GLU A OE1 1 
ATOM   888   O  OE2 . GLU A 1 136 ? 161.540 175.650 206.139 1.00 22.83  ? 136 GLU A OE2 1 
ATOM   889   N  N   . VAL A 1 137 ? 163.554 179.472 201.434 1.00 21.36  ? 137 VAL A N   1 
ATOM   890   C  CA  . VAL A 1 137 ? 163.619 180.794 200.823 1.00 21.36  ? 137 VAL A CA  1 
ATOM   891   C  C   . VAL A 1 137 ? 163.014 180.779 199.426 1.00 21.36  ? 137 VAL A C   1 
ATOM   892   O  O   . VAL A 1 137 ? 162.338 181.731 199.020 1.00 21.36  ? 137 VAL A O   1 
ATOM   893   C  CB  . VAL A 1 137 ? 165.072 181.296 200.808 1.00 21.36  ? 137 VAL A CB  1 
ATOM   894   C  CG1 . VAL A 1 137 ? 165.142 182.650 200.170 1.00 21.36  ? 137 VAL A CG1 1 
ATOM   895   C  CG2 . VAL A 1 137 ? 165.621 181.353 202.217 1.00 21.36  ? 137 VAL A CG2 1 
ATOM   896   N  N   . SER A 1 138 ? 163.233 179.700 198.672 1.00 23.71  ? 138 SER A N   1 
ATOM   897   C  CA  . SER A 1 138 ? 162.638 179.599 197.344 1.00 23.71  ? 138 SER A CA  1 
ATOM   898   C  C   . SER A 1 138 ? 161.118 179.621 197.415 1.00 23.71  ? 138 SER A C   1 
ATOM   899   O  O   . SER A 1 138 ? 160.445 179.844 196.403 1.00 23.71  ? 138 SER A O   1 
ATOM   900   C  CB  . SER A 1 138 ? 163.118 178.330 196.648 1.00 23.71  ? 138 SER A CB  1 
ATOM   901   O  OG  . SER A 1 138 ? 162.494 178.179 195.390 1.00 23.71  ? 138 SER A OG  1 
ATOM   902   N  N   . ASP A 1 139 ? 160.556 179.377 198.601 1.00 24.21  ? 139 ASP A N   1 
ATOM   903   C  CA  . ASP A 1 139 ? 159.111 179.489 198.761 1.00 24.21  ? 139 ASP A CA  1 
ATOM   904   C  C   . ASP A 1 139 ? 158.732 180.886 199.229 1.00 24.21  ? 139 ASP A C   1 
ATOM   905   O  O   . ASP A 1 139 ? 157.658 181.397 198.890 1.00 24.21  ? 139 ASP A O   1 
ATOM   906   C  CB  . ASP A 1 139 ? 158.613 178.433 199.747 1.00 24.21  ? 139 ASP A CB  1 
ATOM   907   C  CG  . ASP A 1 139 ? 157.107 178.269 199.719 1.00 24.21  ? 139 ASP A CG  1 
ATOM   908   O  OD1 . ASP A 1 139 ? 156.438 178.973 198.935 1.00 24.21  ? 139 ASP A OD1 1 
ATOM   909   O  OD2 . ASP A 1 139 ? 156.589 177.430 200.484 1.00 24.21  ? 139 ASP A OD2 1 
ATOM   910   N  N   . MET A 1 140 ? 159.609 181.523 200.006 1.00 27.83  ? 140 MET A N   1 
ATOM   911   C  CA  . MET A 1 140 ? 159.347 182.882 200.463 1.00 27.83  ? 140 MET A CA  1 
ATOM   912   C  C   . MET A 1 140 ? 159.310 183.853 199.293 1.00 27.83  ? 140 MET A C   1 
ATOM   913   O  O   . MET A 1 140 ? 158.443 184.732 199.233 1.00 27.83  ? 140 MET A O   1 
ATOM   914   C  CB  . MET A 1 140 ? 160.409 183.297 201.477 1.00 27.83  ? 140 MET A CB  1 
ATOM   915   C  CG  . MET A 1 140 ? 160.161 184.631 202.137 1.00 27.83  ? 140 MET A CG  1 
ATOM   916   S  SD  . MET A 1 140 ? 161.461 185.014 203.317 1.00 27.83  ? 140 MET A SD  1 
ATOM   917   C  CE  . MET A 1 140 ? 161.102 183.810 204.592 1.00 27.83  ? 140 MET A CE  1 
ATOM   918   N  N   . TYR A 1 141 ? 160.229 183.700 198.345 1.00 26.01  ? 141 TYR A N   1 
ATOM   919   C  CA  . TYR A 1 141 ? 160.314 184.579 197.188 1.00 26.01  ? 141 TYR A CA  1 
ATOM   920   C  C   . TYR A 1 141 ? 159.414 184.133 196.045 1.00 26.01  ? 141 TYR A C   1 
ATOM   921   O  O   . TYR A 1 141 ? 159.379 184.802 195.009 1.00 26.01  ? 141 TYR A O   1 
ATOM   922   C  CB  . TYR A 1 141 ? 161.761 184.664 196.695 1.00 26.01  ? 141 TYR A CB  1 
ATOM   923   C  CG  . TYR A 1 141 ? 162.712 185.262 197.703 1.00 26.01  ? 141 TYR A CG  1 
ATOM   924   C  CD1 . TYR A 1 141 ? 162.239 185.926 198.823 1.00 26.01  ? 141 TYR A CD1 1 
ATOM   925   C  CD2 . TYR A 1 141 ? 164.082 185.158 197.537 1.00 26.01  ? 141 TYR A CD2 1 
ATOM   926   C  CE1 . TYR A 1 141 ? 163.100 186.466 199.748 1.00 26.01  ? 141 TYR A CE1 1 
ATOM   927   C  CE2 . TYR A 1 141 ? 164.952 185.701 198.457 1.00 26.01  ? 141 TYR A CE2 1 
ATOM   928   C  CZ  . TYR A 1 141 ? 164.454 186.351 199.561 1.00 26.01  ? 141 TYR A CZ  1 
ATOM   929   O  OH  . TYR A 1 141 ? 165.314 186.891 200.484 1.00 26.01  ? 141 TYR A OH  1 
ATOM   930   N  N   . GLN A 1 142 ? 158.697 183.023 196.210 1.00 28.77  ? 142 GLN A N   1 
ATOM   931   C  CA  . GLN A 1 142 ? 157.774 182.504 195.200 1.00 28.77  ? 142 GLN A CA  1 
ATOM   932   C  C   . GLN A 1 142 ? 158.487 182.238 193.875 1.00 28.77  ? 142 GLN A C   1 
ATOM   933   O  O   . GLN A 1 142 ? 158.024 182.627 192.802 1.00 28.77  ? 142 GLN A O   1 
ATOM   934   C  CB  . GLN A 1 142 ? 156.582 183.442 195.007 1.00 28.77  ? 142 GLN A CB  1 
ATOM   935   C  CG  . GLN A 1 142 ? 155.712 183.577 196.245 1.00 28.77  ? 142 GLN A CG  1 
ATOM   936   C  CD  . GLN A 1 142 ? 154.509 184.469 196.023 1.00 28.77  ? 142 GLN A CD  1 
ATOM   937   O  OE1 . GLN A 1 142 ? 154.317 185.013 194.938 1.00 28.77  ? 142 GLN A OE1 1 
ATOM   938   N  NE2 . GLN A 1 142 ? 153.696 184.631 197.057 1.00 28.77  ? 142 GLN A NE2 1 
ATOM   939   N  N   . LEU A 1 143 ? 159.636 181.569 193.960 1.00 24.68  ? 143 LEU A N   1 
ATOM   940   C  CA  . LEU A 1 143 ? 160.315 181.017 192.788 1.00 24.68  ? 143 LEU A CA  1 
ATOM   941   C  C   . LEU A 1 143 ? 159.746 179.622 192.574 1.00 24.68  ? 143 LEU A C   1 
ATOM   942   O  O   . LEU A 1 143 ? 160.133 178.662 193.239 1.00 24.68  ? 143 LEU A O   1 
ATOM   943   C  CB  . LEU A 1 143 ? 161.824 180.991 192.990 1.00 24.68  ? 143 LEU A CB  1 
ATOM   944   C  CG  . LEU A 1 143 ? 162.542 182.336 193.086 1.00 24.68  ? 143 LEU A CG  1 
ATOM   945   C  CD1 . LEU A 1 143 ? 163.998 182.138 193.445 1.00 24.68  ? 143 LEU A CD1 1 
ATOM   946   C  CD2 . LEU A 1 143 ? 162.417 183.087 191.779 1.00 24.68  ? 143 LEU A CD2 1 
ATOM   947   N  N   . THR A 1 144 ? 158.811 179.507 191.630 1.00 18.84  ? 144 THR A N   1 
ATOM   948   C  CA  . THR A 1 144 ? 158.016 178.288 191.517 1.00 18.84  ? 144 THR A CA  1 
ATOM   949   C  C   . THR A 1 144 ? 158.866 177.100 191.085 1.00 18.84  ? 144 THR A C   1 
ATOM   950   O  O   . THR A 1 144 ? 158.806 176.027 191.695 1.00 18.84  ? 144 THR A O   1 
ATOM   951   C  CB  . THR A 1 144 ? 156.862 178.506 190.541 1.00 18.84  ? 144 THR A CB  1 
ATOM   952   O  OG1 . THR A 1 144 ? 156.025 179.565 191.020 1.00 18.84  ? 144 THR A OG1 1 
ATOM   953   C  CG2 . THR A 1 144 ? 156.034 177.240 190.405 1.00 18.84  ? 144 THR A CG2 1 
ATOM   954   N  N   . SER A 1 145 ? 159.668 177.270 190.032 1.00 25.50  ? 145 SER A N   1 
ATOM   955   C  CA  . SER A 1 145 ? 160.419 176.141 189.490 1.00 25.50  ? 145 SER A CA  1 
ATOM   956   C  C   . SER A 1 145 ? 161.492 175.661 190.460 1.00 25.50  ? 145 SER A C   1 
ATOM   957   O  O   . SER A 1 145 ? 161.670 174.451 190.649 1.00 25.50  ? 145 SER A O   1 
ATOM   958   C  CB  . SER A 1 145 ? 161.039 176.521 188.149 1.00 25.50  ? 145 SER A CB  1 
ATOM   959   O  OG  . SER A 1 145 ? 160.034 176.792 187.189 1.00 25.50  ? 145 SER A OG  1 
ATOM   960   N  N   . LEU A 1 146 ? 162.216 176.591 191.084 1.00 26.88  ? 146 LEU A N   1 
ATOM   961   C  CA  . LEU A 1 146 ? 163.255 176.197 192.029 1.00 26.88  ? 146 LEU A CA  1 
ATOM   962   C  C   . LEU A 1 146 ? 162.651 175.555 193.271 1.00 26.88  ? 146 LEU A C   1 
ATOM   963   O  O   . LEU A 1 146 ? 163.273 174.689 193.897 1.00 26.88  ? 146 LEU A O   1 
ATOM   964   C  CB  . LEU A 1 146 ? 164.108 177.408 192.401 1.00 26.88  ? 146 LEU A CB  1 
ATOM   965   C  CG  . LEU A 1 146 ? 165.326 177.142 193.282 1.00 26.88  ? 146 LEU A CG  1 
ATOM   966   C  CD1 . LEU A 1 146 ? 166.288 176.218 192.567 1.00 26.88  ? 146 LEU A CD1 1 
ATOM   967   C  CD2 . LEU A 1 146 ? 166.012 178.440 193.657 1.00 26.88  ? 146 LEU A CD2 1 
ATOM   968   N  N   . PHE A 1 147 ? 161.434 175.960 193.641 1.00 24.73  ? 147 PHE A N   1 
ATOM   969   C  CA  . PHE A 1 147 ? 160.759 175.325 194.768 1.00 24.73  ? 147 PHE A CA  1 
ATOM   970   C  C   . PHE A 1 147 ? 160.303 173.917 194.417 1.00 24.73  ? 147 PHE A C   1 
ATOM   971   O  O   . PHE A 1 147 ? 160.442 172.992 195.225 1.00 24.73  ? 147 PHE A O   1 
ATOM   972   C  CB  . PHE A 1 147 ? 159.567 176.168 195.211 1.00 24.73  ? 147 PHE A CB  1 
ATOM   973   C  CG  . PHE A 1 147 ? 158.796 175.569 196.345 1.00 24.73  ? 147 PHE A CG  1 
ATOM   974   C  CD1 . PHE A 1 147 ? 159.286 175.623 197.632 1.00 24.73  ? 147 PHE A CD1 1 
ATOM   975   C  CD2 . PHE A 1 147 ? 157.586 174.944 196.121 1.00 24.73  ? 147 PHE A CD2 1 
ATOM   976   C  CE1 . PHE A 1 147 ? 158.582 175.073 198.674 1.00 24.73  ? 147 PHE A CE1 1 
ATOM   977   C  CE2 . PHE A 1 147 ? 156.878 174.392 197.163 1.00 24.73  ? 147 PHE A CE2 1 
ATOM   978   C  CZ  . PHE A 1 147 ? 157.377 174.457 198.440 1.00 24.73  ? 147 PHE A CZ  1 
ATOM   979   N  N   . GLU A 1 148 ? 159.743 173.738 193.219 1.00 19.38  ? 148 GLU A N   1 
ATOM   980   C  CA  . GLU A 1 148 ? 159.267 172.419 192.818 1.00 19.38  ? 148 GLU A CA  1 
ATOM   981   C  C   . GLU A 1 148 ? 160.420 171.439 192.667 1.00 19.38  ? 148 GLU A C   1 
ATOM   982   O  O   . GLU A 1 148 ? 160.351 170.305 193.157 1.00 19.38  ? 148 GLU A O   1 
ATOM   983   C  CB  . GLU A 1 148 ? 158.476 172.522 191.516 1.00 19.38  ? 148 GLU A CB  1 
ATOM   984   C  CG  . GLU A 1 148 ? 157.168 173.281 191.647 1.00 19.38  ? 148 GLU A CG  1 
ATOM   985   C  CD  . GLU A 1 148 ? 156.418 173.377 190.334 1.00 19.38  ? 148 GLU A CD  1 
ATOM   986   O  OE1 . GLU A 1 148 ? 156.975 172.958 189.299 1.00 19.38  ? 148 GLU A OE1 1 
ATOM   987   O  OE2 . GLU A 1 148 ? 155.272 173.872 190.337 1.00 19.38  ? 148 GLU A OE2 1 
ATOM   988   N  N   . GLU A 1 149 ? 161.499 171.860 192.008 1.00 19.69  ? 149 GLU A N   1 
ATOM   989   C  CA  . GLU A 1 149 ? 162.618 170.948 191.812 1.00 19.69  ? 149 GLU A CA  1 
ATOM   990   C  C   . GLU A 1 149 ? 163.412 170.764 193.100 1.00 19.69  ? 149 GLU A C   1 
ATOM   991   O  O   . GLU A 1 149 ? 163.978 169.691 193.338 1.00 19.69  ? 149 GLU A O   1 
ATOM   992   C  CB  . GLU A 1 149 ? 163.506 171.453 190.683 1.00 19.69  ? 149 GLU A CB  1 
ATOM   993   C  CG  . GLU A 1 149 ? 164.499 170.433 190.197 1.00 19.69  ? 149 GLU A CG  1 
ATOM   994   C  CD  . GLU A 1 149 ? 165.726 170.411 191.052 1.00 19.69  ? 149 GLU A CD  1 
ATOM   995   O  OE1 . GLU A 1 149 ? 166.016 171.456 191.668 1.00 19.69  ? 149 GLU A OE1 1 
ATOM   996   O  OE2 . GLU A 1 149 ? 166.393 169.361 191.114 1.00 19.69  ? 149 GLU A OE2 1 
ATOM   997   N  N   . CYS A 1 150 ? 163.470 171.797 193.941 1.00 25.17  ? 150 CYS A N   1 
ATOM   998   C  CA  . CYS A 1 150 ? 164.035 171.630 195.276 1.00 25.17  ? 150 CYS A CA  1 
ATOM   999   C  C   . CYS A 1 150 ? 163.223 170.633 196.090 1.00 25.17  ? 150 CYS A C   1 
ATOM   1000  O  O   . CYS A 1 150 ? 163.767 169.918 196.940 1.00 25.17  ? 150 CYS A O   1 
ATOM   1001  C  CB  . CYS A 1 150 ? 164.098 172.981 195.985 1.00 25.17  ? 150 CYS A CB  1 
ATOM   1002  S  SG  . CYS A 1 150 ? 164.782 172.924 197.643 1.00 25.17  ? 150 CYS A SG  1 
ATOM   1003  N  N   . SER A 1 151 ? 161.914 170.570 195.839 1.00 23.30  ? 151 SER A N   1 
ATOM   1004  C  CA  . SER A 1 151 ? 161.080 169.563 196.483 1.00 23.30  ? 151 SER A CA  1 
ATOM   1005  C  C   . SER A 1 151 ? 161.356 168.175 195.920 1.00 23.30  ? 151 SER A C   1 
ATOM   1006  O  O   . SER A 1 151 ? 161.363 167.187 196.665 1.00 23.30  ? 151 SER A O   1 
ATOM   1007  C  CB  . SER A 1 151 ? 159.606 169.923 196.319 1.00 23.30  ? 151 SER A CB  1 
ATOM   1008  O  OG  . SER A 1 151 ? 158.777 168.902 196.836 1.00 23.30  ? 151 SER A OG  1 
ATOM   1009  N  N   . ARG A 1 152 ? 161.583 168.075 194.608 1.00 23.90  ? 152 ARG A N   1 
ATOM   1010  C  CA  . ARG A 1 152 ? 161.903 166.776 194.024 1.00 23.90  ? 152 ARG A CA  1 
ATOM   1011  C  C   . ARG A 1 152 ? 163.237 166.254 194.542 1.00 23.90  ? 152 ARG A C   1 
ATOM   1012  O  O   . ARG A 1 152 ? 163.380 165.060 194.825 1.00 23.90  ? 152 ARG A O   1 
ATOM   1013  C  CB  . ARG A 1 152 ? 161.913 166.862 192.498 1.00 23.90  ? 152 ARG A CB  1 
ATOM   1014  C  CG  . ARG A 1 152 ? 160.537 167.033 191.885 1.00 23.90  ? 152 ARG A CG  1 
ATOM   1015  C  CD  . ARG A 1 152 ? 160.554 166.751 190.394 1.00 23.90  ? 152 ARG A CD  1 
ATOM   1016  N  NE  . ARG A 1 152 ? 161.314 167.734 189.629 1.00 23.90  ? 152 ARG A NE  1 
ATOM   1017  C  CZ  . ARG A 1 152 ? 160.785 168.827 189.093 1.00 23.90  ? 152 ARG A CZ  1 
ATOM   1018  N  NH1 . ARG A 1 152 ? 159.491 169.077 189.236 1.00 23.90  ? 152 ARG A NH1 1 
ATOM   1019  N  NH2 . ARG A 1 152 ? 161.546 169.668 188.407 1.00 23.90  ? 152 ARG A NH2 1 
ATOM   1020  N  N   . PHE A 1 153 ? 164.226 167.138 194.682 1.00 29.04  ? 153 PHE A N   1 
ATOM   1021  C  CA  . PHE A 1 153 ? 165.533 166.712 195.171 1.00 29.04  ? 153 PHE A CA  1 
ATOM   1022  C  C   . PHE A 1 153 ? 165.536 166.574 196.687 1.00 29.04  ? 153 PHE A C   1 
ATOM   1023  O  O   . PHE A 1 153 ? 166.443 165.962 197.261 1.00 29.04  ? 153 PHE A O   1 
ATOM   1024  C  CB  . PHE A 1 153 ? 166.606 167.691 194.690 1.00 29.04  ? 153 PHE A CB  1 
ATOM   1025  C  CG  . PHE A 1 153 ? 167.974 167.442 195.263 1.00 29.04  ? 153 PHE A CG  1 
ATOM   1026  C  CD1 . PHE A 1 153 ? 168.663 166.277 194.996 1.00 29.04  ? 153 PHE A CD1 1 
ATOM   1027  C  CD2 . PHE A 1 153 ? 168.602 168.411 196.011 1.00 29.04  ? 153 PHE A CD2 1 
ATOM   1028  C  CE1 . PHE A 1 153 ? 169.927 166.068 195.517 1.00 29.04  ? 153 PHE A CE1 1 
ATOM   1029  C  CE2 . PHE A 1 153 ? 169.861 168.204 196.527 1.00 29.04  ? 153 PHE A CE2 1 
ATOM   1030  C  CZ  . PHE A 1 153 ? 170.524 167.034 196.278 1.00 29.04  ? 153 PHE A CZ  1 
ATOM   1031  N  N   . LEU A 1 154 ? 164.522 167.124 197.354 1.00 48.92  ? 154 LEU A N   1 
ATOM   1032  C  CA  . LEU A 1 154 ? 164.432 166.968 198.801 1.00 48.92  ? 154 LEU A CA  1 
ATOM   1033  C  C   . LEU A 1 154 ? 163.721 165.674 199.172 1.00 48.92  ? 154 LEU A C   1 
ATOM   1034  O  O   . LEU A 1 154 ? 164.046 165.053 200.190 1.00 48.92  ? 154 LEU A O   1 
ATOM   1035  C  CB  . LEU A 1 154 ? 163.720 168.172 199.414 1.00 48.92  ? 154 LEU A CB  1 
ATOM   1036  C  CG  . LEU A 1 154 ? 163.588 168.209 200.934 1.00 48.92  ? 154 LEU A CG  1 
ATOM   1037  C  CD1 . LEU A 1 154 ? 164.947 168.251 201.594 1.00 48.92  ? 154 LEU A CD1 1 
ATOM   1038  C  CD2 . LEU A 1 154 ? 162.769 169.409 201.343 1.00 48.92  ? 154 LEU A CD2 1 
ATOM   1039  N  N   . ALA A 1 155 ? 162.746 165.251 198.365 1.00 27.54  ? 155 ALA A N   1 
ATOM   1040  C  CA  . ALA A 1 155 ? 162.052 163.994 198.615 1.00 27.54  ? 155 ALA A CA  1 
ATOM   1041  C  C   . ALA A 1 155 ? 162.741 162.799 197.973 1.00 27.54  ? 155 ALA A C   1 
ATOM   1042  O  O   . ALA A 1 155 ? 162.354 161.660 198.248 1.00 27.54  ? 155 ALA A O   1 
ATOM   1043  C  CB  . ALA A 1 155 ? 160.608 164.077 198.117 1.00 27.54  ? 155 ALA A CB  1 
ATOM   1044  N  N   . ARG A 1 156 ? 163.741 163.032 197.127 1.00 27.53  ? 156 ARG A N   1 
ATOM   1045  C  CA  . ARG A 1 156 ? 164.512 161.961 196.516 1.00 27.53  ? 156 ARG A CA  1 
ATOM   1046  C  C   . ARG A 1 156 ? 165.510 161.334 197.480 1.00 27.53  ? 156 ARG A C   1 
ATOM   1047  O  O   . ARG A 1 156 ? 165.950 160.204 197.248 1.00 27.53  ? 156 ARG A O   1 
ATOM   1048  C  CB  . ARG A 1 156 ? 165.256 162.500 195.289 1.00 27.53  ? 156 ARG A CB  1 
ATOM   1049  C  CG  . ARG A 1 156 ? 165.913 161.443 194.436 1.00 27.53  ? 156 ARG A CG  1 
ATOM   1050  C  CD  . ARG A 1 156 ? 166.737 162.035 193.305 1.00 27.53  ? 156 ARG A CD  1 
ATOM   1051  N  NE  . ARG A 1 156 ? 165.964 162.784 192.325 1.00 27.53  ? 156 ARG A NE  1 
ATOM   1052  C  CZ  . ARG A 1 156 ? 166.149 164.073 192.071 1.00 27.53  ? 156 ARG A CZ  1 
ATOM   1053  N  NH1 . ARG A 1 156 ? 167.085 164.741 192.724 1.00 27.53  ? 156 ARG A NH1 1 
ATOM   1054  N  NH2 . ARG A 1 156 ? 165.414 164.690 191.158 1.00 27.53  ? 156 ARG A NH2 1 
ATOM   1055  N  N   . THR A 1 157 ? 165.870 162.030 198.554 1.00 25.00  ? 157 THR A N   1 
ATOM   1056  C  CA  . THR A 1 157 ? 166.913 161.580 199.468 1.00 25.00  ? 157 THR A CA  1 
ATOM   1057  C  C   . THR A 1 157 ? 166.435 161.670 200.916 1.00 25.00  ? 157 THR A C   1 
ATOM   1058  O  O   . THR A 1 157 ? 167.138 162.158 201.801 1.00 25.00  ? 157 THR A O   1 
ATOM   1059  C  CB  . THR A 1 157 ? 168.192 162.385 199.249 1.00 25.00  ? 157 THR A CB  1 
ATOM   1060  O  OG1 . THR A 1 157 ? 169.201 161.950 200.169 1.00 25.00  ? 157 THR A OG1 1 
ATOM   1061  C  CG2 . THR A 1 157 ? 167.938 163.879 199.410 1.00 25.00  ? 157 THR A CG2 1 
ATOM   1062  N  N   . VAL A 1 158 ? 165.228 161.177 201.177 1.00 28.45  ? 158 VAL A N   1 
ATOM   1063  C  CA  . VAL A 1 158 ? 164.687 161.099 202.530 1.00 28.45  ? 158 VAL A CA  1 
ATOM   1064  C  C   . VAL A 1 158 ? 165.032 159.719 203.080 1.00 28.45  ? 158 VAL A C   1 
ATOM   1065  O  O   . VAL A 1 158 ? 164.735 158.692 202.465 1.00 28.45  ? 158 VAL A O   1 
ATOM   1066  C  CB  . VAL A 1 158 ? 163.179 161.376 202.569 1.00 28.45  ? 158 VAL A CB  1 
ATOM   1067  C  CG1 . VAL A 1 158 ? 162.899 162.828 202.239 1.00 28.45  ? 158 VAL A CG1 1 
ATOM   1068  C  CG2 . VAL A 1 158 ? 162.434 160.476 201.600 1.00 28.45  ? 158 VAL A CG2 1 
ATOM   1069  N  N   . GLN A 1 159 ? 165.688 159.694 204.238 1.00 36.74  ? 159 GLN A N   1 
ATOM   1070  C  CA  . GLN A 1 159 ? 165.967 158.433 204.935 1.00 36.74  ? 159 GLN A CA  1 
ATOM   1071  C  C   . GLN A 1 159 ? 165.294 158.444 206.304 1.00 36.74  ? 159 GLN A C   1 
ATOM   1072  O  O   . GLN A 1 159 ? 164.669 159.436 206.689 1.00 36.74  ? 159 GLN A O   1 
ATOM   1073  C  CB  . GLN A 1 159 ? 167.475 158.191 205.037 1.00 36.74  ? 159 GLN A CB  1 
ATOM   1074  C  CG  . GLN A 1 159 ? 168.235 159.192 205.893 1.00 36.74  ? 159 GLN A CG  1 
ATOM   1075  C  CD  . GLN A 1 159 ? 168.735 160.384 205.096 1.00 36.74  ? 159 GLN A CD  1 
ATOM   1076  O  OE1 . GLN A 1 159 ? 168.278 160.640 203.982 1.00 36.74  ? 159 GLN A OE1 1 
ATOM   1077  N  NE2 . GLN A 1 159 ? 169.690 161.114 205.663 1.00 36.74  ? 159 GLN A NE2 1 
ATOM   1078  N  N   . VAL A 1 160 ? 165.413 157.342 207.044 1.00 39.41  ? 160 VAL A N   1 
ATOM   1079  C  CA  . VAL A 1 160 ? 164.706 157.161 208.309 1.00 39.41  ? 160 VAL A CA  1 
ATOM   1080  C  C   . VAL A 1 160 ? 165.135 158.227 209.309 1.00 39.41  ? 160 VAL A C   1 
ATOM   1081  O  O   . VAL A 1 160 ? 164.344 158.650 210.159 1.00 39.41  ? 160 VAL A O   1 
ATOM   1082  C  CB  . VAL A 1 160 ? 164.944 155.746 208.869 1.00 39.41  ? 160 VAL A CB  1 
ATOM   1083  C  CG1 . VAL A 1 160 ? 164.244 155.566 210.206 1.00 39.41  ? 160 VAL A CG1 1 
ATOM   1084  C  CG2 . VAL A 1 160 ? 164.473 154.702 207.872 1.00 39.41  ? 160 VAL A CG2 1 
ATOM   1085  N  N   . GLY A 1 161 ? 166.383 158.676 209.208 1.00 37.13  ? 161 GLY A N   1 
ATOM   1086  C  CA  . GLY A 1 161 ? 166.891 159.691 210.108 1.00 37.13  ? 161 GLY A CA  1 
ATOM   1087  C  C   . GLY A 1 161 ? 166.104 160.984 210.060 1.00 37.13  ? 161 GLY A C   1 
ATOM   1088  O  O   . GLY A 1 161 ? 165.884 161.623 211.093 1.00 37.13  ? 161 GLY A O   1 
ATOM   1089  N  N   . ASN A 1 162 ? 165.666 161.377 208.866 1.00 31.78  ? 162 ASN A N   1 
ATOM   1090  C  CA  . ASN A 1 162 ? 164.928 162.620 208.696 1.00 31.78  ? 162 ASN A CA  1 
ATOM   1091  C  C   . ASN A 1 162 ? 163.628 162.452 207.919 1.00 31.78  ? 162 ASN A C   1 
ATOM   1092  O  O   . ASN A 1 162 ? 163.426 163.155 206.926 1.00 31.78  ? 162 ASN A O   1 
ATOM   1093  C  CB  . ASN A 1 162 ? 165.814 163.665 208.010 1.00 31.78  ? 162 ASN A CB  1 
ATOM   1094  C  CG  . ASN A 1 162 ? 166.308 163.215 206.646 1.00 31.78  ? 162 ASN A CG  1 
ATOM   1095  O  OD1 . ASN A 1 162 ? 165.937 162.151 206.154 1.00 31.78  ? 162 ASN A OD1 1 
ATOM   1096  N  ND2 . ASN A 1 162 ? 167.143 164.036 206.025 1.00 31.78  ? 162 ASN A ND2 1 
ATOM   1097  N  N   . CYS A 1 163 ? 162.742 161.546 208.332 1.00 32.52  ? 163 CYS A N   1 
ATOM   1098  C  CA  . CYS A 1 163 ? 161.432 161.476 207.695 1.00 32.52  ? 163 CYS A CA  1 
ATOM   1099  C  C   . CYS A 1 163 ? 160.397 162.240 208.505 1.00 32.52  ? 163 CYS A C   1 
ATOM   1100  O  O   . CYS A 1 163 ? 159.557 162.950 207.942 1.00 32.52  ? 163 CYS A O   1 
ATOM   1101  C  CB  . CYS A 1 163 ? 161.006 160.023 207.514 1.00 32.52  ? 163 CYS A CB  1 
ATOM   1102  S  SG  . CYS A 1 163 ? 160.725 159.152 209.060 1.00 32.52  ? 163 CYS A SG  1 
ATOM   1103  N  N   . LEU A 1 164 ? 160.448 162.118 209.831 1.00 35.18  ? 164 LEU A N   1 
ATOM   1104  C  CA  . LEU A 1 164 ? 159.547 162.856 210.706 1.00 35.18  ? 164 LEU A CA  1 
ATOM   1105  C  C   . LEU A 1 164 ? 159.854 164.346 210.755 1.00 35.18  ? 164 LEU A C   1 
ATOM   1106  O  O   . LEU A 1 164 ? 159.068 165.103 211.335 1.00 35.18  ? 164 LEU A O   1 
ATOM   1107  C  CB  . LEU A 1 164 ? 159.597 162.277 212.119 1.00 35.18  ? 164 LEU A CB  1 
ATOM   1108  C  CG  . LEU A 1 164 ? 159.041 160.863 212.265 1.00 35.18  ? 164 LEU A CG  1 
ATOM   1109  C  CD1 . LEU A 1 164 ? 159.323 160.335 213.652 1.00 35.18  ? 164 LEU A CD1 1 
ATOM   1110  C  CD2 . LEU A 1 164 ? 157.548 160.849 211.978 1.00 35.18  ? 164 LEU A CD2 1 
ATOM   1111  N  N   . GLN A 1 165 ? 160.973 164.781 210.182 1.00 29.33  ? 165 GLN A N   1 
ATOM   1112  C  CA  . GLN A 1 165 ? 161.263 166.201 210.043 1.00 29.33  ? 165 GLN A CA  1 
ATOM   1113  C  C   . GLN A 1 165 ? 160.931 166.725 208.657 1.00 29.33  ? 165 GLN A C   1 
ATOM   1114  O  O   . GLN A 1 165 ? 160.521 167.882 208.522 1.00 29.33  ? 165 GLN A O   1 
ATOM   1115  C  CB  . GLN A 1 165 ? 162.738 166.473 210.352 1.00 29.33  ? 165 GLN A CB  1 
ATOM   1116  C  CG  . GLN A 1 165 ? 163.074 167.939 210.551 1.00 29.33  ? 165 GLN A CG  1 
ATOM   1117  C  CD  . GLN A 1 165 ? 163.384 168.655 209.258 1.00 29.33  ? 165 GLN A CD  1 
ATOM   1118  O  OE1 . GLN A 1 165 ? 163.881 168.056 208.306 1.00 29.33  ? 165 GLN A OE1 1 
ATOM   1119  N  NE2 . GLN A 1 165 ? 163.087 169.948 209.215 1.00 29.33  ? 165 GLN A NE2 1 
ATOM   1120  N  N   . VAL A 1 166 ? 161.092 165.893 207.628 1.00 26.06  ? 166 VAL A N   1 
ATOM   1121  C  CA  . VAL A 1 166 ? 160.684 166.280 206.284 1.00 26.06  ? 166 VAL A CA  1 
ATOM   1122  C  C   . VAL A 1 166 ? 159.163 166.258 206.156 1.00 26.06  ? 166 VAL A C   1 
ATOM   1123  O  O   . VAL A 1 166 ? 158.595 166.967 205.317 1.00 26.06  ? 166 VAL A O   1 
ATOM   1124  C  CB  . VAL A 1 166 ? 161.389 165.373 205.257 1.00 26.06  ? 166 VAL A CB  1 
ATOM   1125  C  CG1 . VAL A 1 166 ? 160.844 165.574 203.883 1.00 26.06  ? 166 VAL A CG1 1 
ATOM   1126  C  CG2 . VAL A 1 166 ? 162.870 165.679 205.236 1.00 26.06  ? 166 VAL A CG2 1 
ATOM   1127  N  N   . MET A 1 167 ? 158.472 165.474 206.989 1.00 29.68  ? 167 MET A N   1 
ATOM   1128  C  CA  . MET A 1 167 ? 157.018 165.588 207.060 1.00 29.68  ? 167 MET A CA  1 
ATOM   1129  C  C   . MET A 1 167 ? 156.608 166.948 207.606 1.00 29.68  ? 167 MET A C   1 
ATOM   1130  O  O   . MET A 1 167 ? 155.750 167.628 207.034 1.00 29.68  ? 167 MET A O   1 
ATOM   1131  C  CB  . MET A 1 167 ? 156.425 164.477 207.926 1.00 29.68  ? 167 MET A CB  1 
ATOM   1132  C  CG  . MET A 1 167 ? 156.466 163.098 207.311 1.00 29.68  ? 167 MET A CG  1 
ATOM   1133  S  SD  . MET A 1 167 ? 155.717 161.871 208.394 1.00 29.68  ? 167 MET A SD  1 
ATOM   1134  C  CE  . MET A 1 167 ? 153.997 162.345 208.271 1.00 29.68  ? 167 MET A CE  1 
ATOM   1135  N  N   . TRP A 1 168 ? 157.202 167.350 208.732 1.00 30.85  ? 168 TRP A N   1 
ATOM   1136  C  CA  . TRP A 1 168 ? 156.949 168.673 209.290 1.00 30.85  ? 168 TRP A CA  1 
ATOM   1137  C  C   . TRP A 1 168 ? 157.258 169.770 208.283 1.00 30.85  ? 168 TRP A C   1 
ATOM   1138  O  O   . TRP A 1 168 ? 156.457 170.697 208.100 1.00 30.85  ? 168 TRP A O   1 
ATOM   1139  C  CB  . TRP A 1 168 ? 157.786 168.859 210.554 1.00 30.85  ? 168 TRP A CB  1 
ATOM   1140  C  CG  . TRP A 1 168 ? 157.583 170.160 211.244 1.00 30.85  ? 168 TRP A CG  1 
ATOM   1141  C  CD1 . TRP A 1 168 ? 158.403 171.248 211.198 1.00 30.85  ? 168 TRP A CD1 1 
ATOM   1142  C  CD2 . TRP A 1 168 ? 156.496 170.512 212.106 1.00 30.85  ? 168 TRP A CD2 1 
ATOM   1143  N  NE1 . TRP A 1 168 ? 157.890 172.260 211.972 1.00 30.85  ? 168 TRP A NE1 1 
ATOM   1144  C  CE2 . TRP A 1 168 ? 156.718 171.833 212.540 1.00 30.85  ? 168 TRP A CE2 1 
ATOM   1145  C  CE3 . TRP A 1 168 ? 155.354 169.839 212.549 1.00 30.85  ? 168 TRP A CE3 1 
ATOM   1146  C  CZ2 . TRP A 1 168 ? 155.842 172.494 213.395 1.00 30.85  ? 168 TRP A CZ2 1 
ATOM   1147  C  CZ3 . TRP A 1 168 ? 154.486 170.497 213.397 1.00 30.85  ? 168 TRP A CZ3 1 
ATOM   1148  C  CH2 . TRP A 1 168 ? 154.734 171.811 213.811 1.00 30.85  ? 168 TRP A CH2 1 
ATOM   1149  N  N   . LEU A 1 169 ? 158.408 169.675 207.616 1.00 28.02  ? 169 LEU A N   1 
ATOM   1150  C  CA  . LEU A 1 169 ? 158.785 170.649 206.600 1.00 28.02  ? 169 LEU A CA  1 
ATOM   1151  C  C   . LEU A 1 169 ? 157.800 170.680 205.439 1.00 28.02  ? 169 LEU A C   1 
ATOM   1152  O  O   . LEU A 1 169 ? 157.509 171.757 204.910 1.00 28.02  ? 169 LEU A O   1 
ATOM   1153  C  CB  . LEU A 1 169 ? 160.192 170.343 206.094 1.00 28.02  ? 169 LEU A CB  1 
ATOM   1154  C  CG  . LEU A 1 169 ? 160.796 171.298 205.076 1.00 28.02  ? 169 LEU A CG  1 
ATOM   1155  C  CD1 . LEU A 1 169 ? 160.897 172.666 205.683 1.00 28.02  ? 169 LEU A CD1 1 
ATOM   1156  C  CD2 . LEU A 1 169 ? 162.161 170.802 204.675 1.00 28.02  ? 169 LEU A CD2 1 
ATOM   1157  N  N   . ALA A 1 170 ? 157.278 169.523 205.031 1.00 25.88  ? 170 ALA A N   1 
ATOM   1158  C  CA  . ALA A 1 170 ? 156.291 169.491 203.959 1.00 25.88  ? 170 ALA A CA  1 
ATOM   1159  C  C   . ALA A 1 170 ? 154.940 170.006 204.429 1.00 25.88  ? 170 ALA A C   1 
ATOM   1160  O  O   . ALA A 1 170 ? 154.102 170.399 203.611 1.00 25.88  ? 170 ALA A O   1 
ATOM   1161  C  CB  . ALA A 1 170 ? 156.140 168.072 203.422 1.00 25.88  ? 170 ALA A CB  1 
ATOM   1162  N  N   . ASP A 1 171 ? 154.710 170.002 205.741 1.00 33.44  ? 171 ASP A N   1 
ATOM   1163  C  CA  . ASP A 1 171 ? 153.409 170.404 206.258 1.00 33.44  ? 171 ASP A CA  1 
ATOM   1164  C  C   . ASP A 1 171 ? 153.365 171.900 206.537 1.00 33.44  ? 171 ASP A C   1 
ATOM   1165  O  O   . ASP A 1 171 ? 152.290 172.510 206.501 1.00 33.44  ? 171 ASP A O   1 
ATOM   1166  C  CB  . ASP A 1 171 ? 153.082 169.605 207.517 1.00 33.44  ? 171 ASP A CB  1 
ATOM   1167  C  CG  . ASP A 1 171 ? 151.668 169.825 207.987 1.00 33.44  ? 171 ASP A CG  1 
ATOM   1168  O  OD1 . ASP A 1 171 ? 150.743 169.299 207.336 1.00 33.44  ? 171 ASP A OD1 1 
ATOM   1169  O  OD2 . ASP A 1 171 ? 151.479 170.524 209.004 1.00 33.44  ? 171 ASP A OD2 1 
ATOM   1170  N  N   . ARG A 1 172 ? 154.518 172.511 206.818 1.00 32.35  ? 172 ARG A N   1 
ATOM   1171  C  CA  . ARG A 1 172 ? 154.538 173.959 207.000 1.00 32.35  ? 172 ARG A CA  1 
ATOM   1172  C  C   . ARG A 1 172 ? 154.329 174.689 205.679 1.00 32.35  ? 172 ARG A C   1 
ATOM   1173  O  O   . ARG A 1 172 ? 153.734 175.771 205.652 1.00 32.35  ? 172 ARG A O   1 
ATOM   1174  C  CB  . ARG A 1 172 ? 155.851 174.405 207.637 1.00 32.35  ? 172 ARG A CB  1 
ATOM   1175  C  CG  . ARG A 1 172 ? 156.054 173.945 209.061 1.00 32.35  ? 172 ARG A CG  1 
ATOM   1176  C  CD  . ARG A 1 172 ? 157.363 174.490 209.608 1.00 32.35  ? 172 ARG A CD  1 
ATOM   1177  N  NE  . ARG A 1 172 ? 157.327 175.944 209.745 1.00 32.35  ? 172 ARG A NE  1 
ATOM   1178  C  CZ  . ARG A 1 172 ? 158.010 176.787 208.978 1.00 32.35  ? 172 ARG A CZ  1 
ATOM   1179  N  NH1 . ARG A 1 172 ? 158.788 176.324 208.010 1.00 32.35  ? 172 ARG A NH1 1 
ATOM   1180  N  NH2 . ARG A 1 172 ? 157.913 178.095 209.176 1.00 32.35  ? 172 ARG A NH2 1 
ATOM   1181  N  N   . HIS A 1 173 ? 154.811 174.118 204.578 1.00 23.47  ? 173 HIS A N   1 
ATOM   1182  C  CA  . HIS A 1 173 ? 154.775 174.788 203.286 1.00 23.47  ? 173 HIS A CA  1 
ATOM   1183  C  C   . HIS A 1 173 ? 153.684 174.265 202.361 1.00 23.47  ? 173 HIS A C   1 
ATOM   1184  O  O   . HIS A 1 173 ? 153.682 174.619 201.178 1.00 23.47  ? 173 HIS A O   1 
ATOM   1185  C  CB  . HIS A 1 173 ? 156.135 174.669 202.595 1.00 23.47  ? 173 HIS A CB  1 
ATOM   1186  C  CG  . HIS A 1 173 ? 157.233 175.392 203.307 1.00 23.47  ? 173 HIS A CG  1 
ATOM   1187  N  ND1 . HIS A 1 173 ? 157.363 176.763 203.275 1.00 23.47  ? 173 HIS A ND1 1 
ATOM   1188  C  CD2 . HIS A 1 173 ? 158.247 174.937 204.078 1.00 23.47  ? 173 HIS A CD2 1 
ATOM   1189  C  CE1 . HIS A 1 173 ? 158.412 177.121 203.992 1.00 23.47  ? 173 HIS A CE1 1 
ATOM   1190  N  NE2 . HIS A 1 173 ? 158.966 176.031 204.490 1.00 23.47  ? 173 HIS A NE2 1 
ATOM   1191  N  N   . SER A 1 174 ? 152.766 173.440 202.868 1.00 24.84  ? 174 SER A N   1 
ATOM   1192  C  CA  . SER A 1 174 ? 151.610 172.963 202.109 1.00 24.84  ? 174 SER A CA  1 
ATOM   1193  C  C   . SER A 1 174 ? 152.037 172.301 200.797 1.00 24.84  ? 174 SER A C   1 
ATOM   1194  O  O   . SER A 1 174 ? 151.633 172.700 199.703 1.00 24.84  ? 174 SER A O   1 
ATOM   1195  C  CB  . SER A 1 174 ? 150.622 174.106 201.854 1.00 24.84  ? 174 SER A CB  1 
ATOM   1196  O  OG  . SER A 1 174 ? 149.531 173.668 201.065 1.00 24.84  ? 174 SER A OG  1 
ATOM   1197  N  N   . ASP A 1 175 ? 152.873 171.270 200.927 1.00 24.54  ? 175 ASP A N   1 
ATOM   1198  C  CA  . ASP A 1 175 ? 153.374 170.500 199.790 1.00 24.54  ? 175 ASP A CA  1 
ATOM   1199  C  C   . ASP A 1 175 ? 152.842 169.078 199.909 1.00 24.54  ? 175 ASP A C   1 
ATOM   1200  O  O   . ASP A 1 175 ? 153.263 168.321 200.796 1.00 24.54  ? 175 ASP A O   1 
ATOM   1201  C  CB  . ASP A 1 175 ? 154.900 170.517 199.741 1.00 24.54  ? 175 ASP A CB  1 
ATOM   1202  C  CG  . ASP A 1 175 ? 155.448 169.945 198.450 1.00 24.54  ? 175 ASP A CG  1 
ATOM   1203  O  OD1 . ASP A 1 175 ? 154.646 169.520 197.594 1.00 24.54  ? 175 ASP A OD1 1 
ATOM   1204  O  OD2 . ASP A 1 175 ? 156.686 169.917 198.290 1.00 24.54  ? 175 ASP A OD2 1 
ATOM   1205  N  N   . PRO A 1 176 ? 151.913 168.673 199.044 1.00 25.65  ? 176 PRO A N   1 
ATOM   1206  C  CA  . PRO A 1 176 ? 151.353 167.318 199.147 1.00 25.65  ? 176 PRO A CA  1 
ATOM   1207  C  C   . PRO A 1 176 ? 152.294 166.243 198.623 1.00 25.65  ? 176 PRO A C   1 
ATOM   1208  O  O   . PRO A 1 176 ? 152.458 165.197 199.259 1.00 25.65  ? 176 PRO A O   1 
ATOM   1209  C  CB  . PRO A 1 176 ? 150.075 167.407 198.304 1.00 25.65  ? 176 PRO A CB  1 
ATOM   1210  C  CG  . PRO A 1 176 ? 150.361 168.480 197.312 1.00 25.65  ? 176 PRO A CG  1 
ATOM   1211  C  CD  . PRO A 1 176 ? 151.238 169.480 198.013 1.00 25.65  ? 176 PRO A CD  1 
ATOM   1212  N  N   . GLU A 1 177 ? 152.912 166.487 197.467 1.00 28.43  ? 177 GLU A N   1 
ATOM   1213  C  CA  . GLU A 1 177 ? 153.833 165.547 196.839 1.00 28.43  ? 177 GLU A CA  1 
ATOM   1214  C  C   . GLU A 1 177 ? 154.966 165.127 197.759 1.00 28.43  ? 177 GLU A C   1 
ATOM   1215  O  O   . GLU A 1 177 ? 155.283 163.935 197.838 1.00 28.43  ? 177 GLU A O   1 
ATOM   1216  C  CB  . GLU A 1 177 ? 154.418 166.158 195.557 1.00 28.43  ? 177 GLU A CB  1 
ATOM   1217  C  CG  . GLU A 1 177 ? 155.391 165.245 194.826 1.00 28.43  ? 177 GLU A CG  1 
ATOM   1218  C  CD  . GLU A 1 177 ? 155.974 165.884 193.579 1.00 28.43  ? 177 GLU A CD  1 
ATOM   1219  O  OE1 . GLU A 1 177 ? 155.638 167.052 193.293 1.00 28.43  ? 177 GLU A OE1 1 
ATOM   1220  O  OE2 . GLU A 1 177 ? 156.773 165.219 192.888 1.00 28.43  ? 177 GLU A OE2 1 
ATOM   1221  N  N   . LEU A 1 178 ? 155.593 166.076 198.454 1.00 25.76  ? 178 LEU A N   1 
ATOM   1222  C  CA  . LEU A 1 178 ? 156.709 165.736 199.327 1.00 25.76  ? 178 LEU A CA  1 
ATOM   1223  C  C   . LEU A 1 178 ? 156.225 165.254 200.688 1.00 25.76  ? 178 LEU A C   1 
ATOM   1224  O  O   . LEU A 1 178 ? 156.968 164.575 201.404 1.00 25.76  ? 178 LEU A O   1 
ATOM   1225  C  CB  . LEU A 1 178 ? 157.642 166.941 199.458 1.00 25.76  ? 178 LEU A CB  1 
ATOM   1226  C  CG  . LEU A 1 178 ? 158.995 166.770 200.141 1.00 25.76  ? 178 LEU A CG  1 
ATOM   1227  C  CD1 . LEU A 1 178 ? 160.013 167.679 199.508 1.00 25.76  ? 178 LEU A CD1 1 
ATOM   1228  C  CD2 . LEU A 1 178 ? 158.874 167.130 201.582 1.00 25.76  ? 178 LEU A CD2 1 
ATOM   1229  N  N   . TYR A 1 179 ? 154.986 165.582 201.058 1.00 29.21  ? 179 TYR A N   1 
ATOM   1230  C  CA  . TYR A 1 179 ? 154.419 165.044 202.289 1.00 29.21  ? 179 TYR A CA  1 
ATOM   1231  C  C   . TYR A 1 179 ? 154.144 163.555 202.151 1.00 29.21  ? 179 TYR A C   1 
ATOM   1232  O  O   . TYR A 1 179 ? 154.316 162.790 203.106 1.00 29.21  ? 179 TYR A O   1 
ATOM   1233  C  CB  . TYR A 1 179 ? 153.139 165.796 202.642 1.00 29.21  ? 179 TYR A CB  1 
ATOM   1234  C  CG  . TYR A 1 179 ? 152.520 165.407 203.961 1.00 29.21  ? 179 TYR A CG  1 
ATOM   1235  C  CD1 . TYR A 1 179 ? 153.062 165.846 205.157 1.00 29.21  ? 179 TYR A CD1 1 
ATOM   1236  C  CD2 . TYR A 1 179 ? 151.384 164.619 204.010 1.00 29.21  ? 179 TYR A CD2 1 
ATOM   1237  C  CE1 . TYR A 1 179 ? 152.496 165.502 206.365 1.00 29.21  ? 179 TYR A CE1 1 
ATOM   1238  C  CE2 . TYR A 1 179 ? 150.812 164.271 205.214 1.00 29.21  ? 179 TYR A CE2 1 
ATOM   1239  C  CZ  . TYR A 1 179 ? 151.372 164.715 206.387 1.00 29.21  ? 179 TYR A CZ  1 
ATOM   1240  O  OH  . TYR A 1 179 ? 150.805 164.369 207.588 1.00 29.21  ? 179 TYR A OH  1 
ATOM   1241  N  N   . THR A 1 180 ? 153.720 163.125 200.962 1.00 24.82  ? 180 THR A N   1 
ATOM   1242  C  CA  . THR A 1 180 ? 153.522 161.702 200.715 1.00 24.82  ? 180 THR A CA  1 
ATOM   1243  C  C   . THR A 1 180 ? 154.850 160.959 200.695 1.00 24.82  ? 180 THR A C   1 
ATOM   1244  O  O   . THR A 1 180 ? 154.990 159.904 201.325 1.00 24.82  ? 180 THR A O   1 
ATOM   1245  C  CB  . THR A 1 180 ? 152.779 161.497 199.398 1.00 24.82  ? 180 THR A CB  1 
ATOM   1246  O  OG1 . THR A 1 180 ? 151.488 162.113 199.475 1.00 24.82  ? 180 THR A OG1 1 
ATOM   1247  C  CG2 . THR A 1 180 ? 152.619 160.018 199.104 1.00 24.82  ? 180 THR A CG2 1 
ATOM   1248  N  N   . ALA A 1 181 ? 155.840 161.492 199.976 1.00 22.76  ? 181 ALA A N   1 
ATOM   1249  C  CA  . ALA A 1 181 ? 157.154 160.865 199.937 1.00 22.76  ? 181 ALA A CA  1 
ATOM   1250  C  C   . ALA A 1 181 ? 157.855 160.906 201.286 1.00 22.76  ? 181 ALA A C   1 
ATOM   1251  O  O   . ALA A 1 181 ? 158.765 160.105 201.520 1.00 22.76  ? 181 ALA A O   1 
ATOM   1252  C  CB  . ALA A 1 181 ? 158.025 161.536 198.878 1.00 22.76  ? 181 ALA A CB  1 
ATOM   1253  N  N   . ALA A 1 182 ? 157.462 161.818 202.169 1.00 25.42  ? 182 ALA A N   1 
ATOM   1254  C  CA  . ALA A 1 182 ? 157.992 161.874 203.522 1.00 25.42  ? 182 ALA A CA  1 
ATOM   1255  C  C   . ALA A 1 182 ? 157.205 161.011 204.492 1.00 25.42  ? 182 ALA A C   1 
ATOM   1256  O  O   . ALA A 1 182 ? 157.721 160.676 205.562 1.00 25.42  ? 182 ALA A O   1 
ATOM   1257  C  CB  . ALA A 1 182 ? 158.008 163.318 204.026 1.00 25.42  ? 182 ALA A CB  1 
ATOM   1258  N  N   . LYS A 1 183 ? 155.977 160.644 204.142 1.00 31.66  ? 183 LYS A N   1 
ATOM   1259  C  CA  . LYS A 1 183 ? 155.117 159.813 204.973 1.00 31.66  ? 183 LYS A CA  1 
ATOM   1260  C  C   . LYS A 1 183 ? 155.279 158.327 204.685 1.00 31.66  ? 183 LYS A C   1 
ATOM   1261  O  O   . LYS A 1 183 ? 155.188 157.508 205.606 1.00 31.66  ? 183 LYS A O   1 
ATOM   1262  C  CB  . LYS A 1 183 ? 153.657 160.227 204.769 1.00 31.66  ? 183 LYS A CB  1 
ATOM   1263  C  CG  . LYS A 1 183 ? 152.652 159.477 205.604 1.00 31.66  ? 183 LYS A CG  1 
ATOM   1264  C  CD  . LYS A 1 183 ? 151.271 160.070 205.406 1.00 31.66  ? 183 LYS A CD  1 
ATOM   1265  C  CE  . LYS A 1 183 ? 150.724 159.734 204.032 1.00 31.66  ? 183 LYS A CE  1 
ATOM   1266  N  NZ  . LYS A 1 183 ? 149.335 160.232 203.850 1.00 31.66  ? 183 LYS A NZ  1 
ATOM   1267  N  N   . HIS A 1 184 ? 155.524 157.965 203.423 1.00 36.41  ? 184 HIS A N   1 
ATOM   1268  C  CA  . HIS A 1 184 ? 155.770 156.568 203.078 1.00 36.41  ? 184 HIS A CA  1 
ATOM   1269  C  C   . HIS A 1 184 ? 156.961 156.009 203.846 1.00 36.41  ? 184 HIS A C   1 
ATOM   1270  O  O   . HIS A 1 184 ? 156.878 154.921 204.428 1.00 36.41  ? 184 HIS A O   1 
ATOM   1271  C  CB  . HIS A 1 184 ? 155.994 156.437 201.572 1.00 36.41  ? 184 HIS A CB  1 
ATOM   1272  C  CG  . HIS A 1 184 ? 156.271 155.038 201.121 1.00 36.41  ? 184 HIS A CG  1 
ATOM   1273  N  ND1 . HIS A 1 184 ? 155.291 154.073 201.041 1.00 36.41  ? 184 HIS A ND1 1 
ATOM   1274  C  CD2 . HIS A 1 184 ? 157.420 154.441 200.724 1.00 36.41  ? 184 HIS A CD2 1 
ATOM   1275  C  CE1 . HIS A 1 184 ? 155.824 152.942 200.615 1.00 36.41  ? 184 HIS A CE1 1 
ATOM   1276  N  NE2 . HIS A 1 184 ? 157.114 153.138 200.415 1.00 36.41  ? 184 HIS A NE2 1 
ATOM   1277  N  N   . CYS A 1 185 ? 158.077 156.740 203.864 1.00 37.97  ? 185 CYS A N   1 
ATOM   1278  C  CA  . CYS A 1 185 ? 159.252 156.270 204.589 1.00 37.97  ? 185 CYS A CA  1 
ATOM   1279  C  C   . CYS A 1 185 ? 159.003 156.251 206.092 1.00 37.97  ? 185 CYS A C   1 
ATOM   1280  O  O   . CYS A 1 185 ? 159.620 155.463 206.818 1.00 37.97  ? 185 CYS A O   1 
ATOM   1281  C  CB  . CYS A 1 185 ? 160.458 157.146 204.257 1.00 37.97  ? 185 CYS A CB  1 
ATOM   1282  S  SG  . CYS A 1 185 ? 161.995 156.638 205.056 1.00 37.97  ? 185 CYS A SG  1 
ATOM   1283  N  N   . ALA A 1 186 ? 158.101 157.106 206.578 1.00 37.61  ? 186 ALA A N   1 
ATOM   1284  C  CA  . ALA A 1 186 ? 157.841 157.157 208.012 1.00 37.61  ? 186 ALA A CA  1 
ATOM   1285  C  C   . ALA A 1 186 ? 156.990 155.979 208.462 1.00 37.61  ? 186 ALA A C   1 
ATOM   1286  O  O   . ALA A 1 186 ? 157.233 155.403 209.528 1.00 37.61  ? 186 ALA A O   1 
ATOM   1287  C  CB  . ALA A 1 186 ? 157.166 158.477 208.378 1.00 37.61  ? 186 ALA A CB  1 
ATOM   1288  N  N   . LYS A 1 187 ? 155.984 155.604 207.669 1.00 44.40  ? 187 LYS A N   1 
ATOM   1289  C  CA  . LYS A 1 187 ? 155.136 154.483 208.056 1.00 44.40  ? 187 LYS A CA  1 
ATOM   1290  C  C   . LYS A 1 187 ? 155.751 153.139 207.691 1.00 44.40  ? 187 LYS A C   1 
ATOM   1291  O  O   . LYS A 1 187 ? 155.413 152.129 208.315 1.00 44.40  ? 187 LYS A O   1 
ATOM   1292  C  CB  . LYS A 1 187 ? 153.754 154.606 207.415 1.00 44.40  ? 187 LYS A CB  1 
ATOM   1293  C  CG  . LYS A 1 187 ? 153.752 154.430 205.914 1.00 44.40  ? 187 LYS A CG  1 
ATOM   1294  C  CD  . LYS A 1 187 ? 152.355 154.568 205.347 1.00 44.40  ? 187 LYS A CD  1 
ATOM   1295  C  CE  . LYS A 1 187 ? 152.359 154.341 203.849 1.00 44.40  ? 187 LYS A CE  1 
ATOM   1296  N  NZ  . LYS A 1 187 ? 151.003 154.479 203.265 1.00 44.40  ? 187 LYS A NZ  1 
ATOM   1297  N  N   . THR A 1 188 ? 156.640 153.099 206.696 1.00 47.36  ? 188 THR A N   1 
ATOM   1298  C  CA  . THR A 1 188 ? 157.302 151.844 206.357 1.00 47.36  ? 188 THR A CA  1 
ATOM   1299  C  C   . THR A 1 188 ? 158.267 151.414 207.456 1.00 47.36  ? 188 THR A C   1 
ATOM   1300  O  O   . THR A 1 188 ? 158.263 150.250 207.872 1.00 47.36  ? 188 THR A O   1 
ATOM   1301  C  CB  . THR A 1 188 ? 158.036 151.977 205.023 1.00 47.36  ? 188 THR A CB  1 
ATOM   1302  O  OG1 . THR A 1 188 ? 157.090 152.249 203.981 1.00 47.36  ? 188 THR A OG1 1 
ATOM   1303  C  CG2 . THR A 1 188 ? 158.786 150.699 204.697 1.00 47.36  ? 188 THR A CG2 1 
ATOM   1304  N  N   . HIS A 1 189 ? 159.094 152.337 207.940 1.00 51.28  ? 189 HIS A N   1 
ATOM   1305  C  CA  . HIS A 1 189 ? 160.053 152.068 209.009 1.00 51.28  ? 189 HIS A CA  1 
ATOM   1306  C  C   . HIS A 1 189 ? 159.527 152.532 210.360 1.00 51.28  ? 189 HIS A C   1 
ATOM   1307  O  O   . HIS A 1 189 ? 160.191 153.297 211.065 1.00 51.28  ? 189 HIS A O   1 
ATOM   1308  C  CB  . HIS A 1 189 ? 161.386 152.736 208.694 1.00 51.28  ? 189 HIS A CB  1 
ATOM   1309  C  CG  . HIS A 1 189 ? 162.011 152.262 207.420 1.00 51.28  ? 189 HIS A CG  1 
ATOM   1310  N  ND1 . HIS A 1 189 ? 162.653 151.047 207.310 1.00 51.28  ? 189 HIS A ND1 1 
ATOM   1311  C  CD2 . HIS A 1 189 ? 162.082 152.837 206.196 1.00 51.28  ? 189 HIS A CD2 1 
ATOM   1312  C  CE1 . HIS A 1 189 ? 163.098 150.897 206.075 1.00 51.28  ? 189 HIS A CE1 1 
ATOM   1313  N  NE2 . HIS A 1 189 ? 162.766 151.970 205.379 1.00 51.28  ? 189 HIS A NE2 1 
ATOM   1314  N  N   . LEU A 1 190 ? 158.335 152.075 210.747 1.00 55.86  ? 190 LEU A N   1 
ATOM   1315  C  CA  . LEU A 1 190 ? 157.671 152.638 211.919 1.00 55.86  ? 190 LEU A CA  1 
ATOM   1316  C  C   . LEU A 1 190 ? 158.272 152.110 213.216 1.00 55.86  ? 190 LEU A C   1 
ATOM   1317  O  O   . LEU A 1 190 ? 158.378 152.848 214.203 1.00 55.86  ? 190 LEU A O   1 
ATOM   1318  C  CB  . LEU A 1 190 ? 156.172 152.340 211.862 1.00 55.86  ? 190 LEU A CB  1 
ATOM   1319  C  CG  . LEU A 1 190 ? 155.293 152.956 212.951 1.00 55.86  ? 190 LEU A CG  1 
ATOM   1320  C  CD1 . LEU A 1 190 ? 155.336 154.470 212.870 1.00 55.86  ? 190 LEU A CD1 1 
ATOM   1321  C  CD2 . LEU A 1 190 ? 153.864 152.457 212.834 1.00 55.86  ? 190 LEU A CD2 1 
ATOM   1322  N  N   . ALA A 1 191 ? 158.667 150.836 213.238 1.00 61.74  ? 191 ALA A N   1 
ATOM   1323  C  CA  . ALA A 1 191 ? 159.207 150.257 214.465 1.00 61.74  ? 191 ALA A CA  1 
ATOM   1324  C  C   . ALA A 1 191 ? 160.558 150.864 214.820 1.00 61.74  ? 191 ALA A C   1 
ATOM   1325  O  O   . ALA A 1 191 ? 160.932 150.915 215.998 1.00 61.74  ? 191 ALA A O   1 
ATOM   1326  C  CB  . ALA A 1 191 ? 159.324 148.740 214.325 1.00 61.74  ? 191 ALA A CB  1 
ATOM   1327  N  N   . GLN A 1 192 ? 161.304 151.331 213.818 1.00 58.50  ? 192 GLN A N   1 
ATOM   1328  C  CA  . GLN A 1 192 ? 162.624 151.894 214.077 1.00 58.50  ? 192 GLN A CA  1 
ATOM   1329  C  C   . GLN A 1 192 ? 162.527 153.302 214.655 1.00 58.50  ? 192 GLN A C   1 
ATOM   1330  O  O   . GLN A 1 192 ? 163.526 153.843 215.145 1.00 58.50  ? 192 GLN A O   1 
ATOM   1331  C  CB  . GLN A 1 192 ? 163.445 151.879 212.785 1.00 58.50  ? 192 GLN A CB  1 
ATOM   1332  C  CG  . GLN A 1 192 ? 164.911 152.253 212.936 1.00 58.50  ? 192 GLN A CG  1 
ATOM   1333  C  CD  . GLN A 1 192 ? 165.677 152.127 211.634 1.00 58.50  ? 192 GLN A CD  1 
ATOM   1334  O  OE1 . GLN A 1 192 ? 165.108 151.790 210.596 1.00 58.50  ? 192 GLN A OE1 1 
ATOM   1335  N  NE2 . GLN A 1 192 ? 166.977 152.395 211.683 1.00 58.50  ? 192 GLN A NE2 1 
ATOM   1336  N  N   . LEU A 1 193 ? 161.337 153.897 214.630 1.00 58.89  ? 193 LEU A N   1 
ATOM   1337  C  CA  . LEU A 1 193 ? 161.127 155.266 215.081 1.00 58.89  ? 193 LEU A CA  1 
ATOM   1338  C  C   . LEU A 1 193 ? 160.331 155.361 216.376 1.00 58.89  ? 193 LEU A C   1 
ATOM   1339  O  O   . LEU A 1 193 ? 160.215 156.457 216.931 1.00 58.89  ? 193 LEU A O   1 
ATOM   1340  C  CB  . LEU A 1 193 ? 160.402 156.068 213.997 1.00 58.89  ? 193 LEU A CB  1 
ATOM   1341  C  CG  . LEU A 1 193 ? 161.132 156.318 212.681 1.00 58.89  ? 193 LEU A CG  1 
ATOM   1342  C  CD1 . LEU A 1 193 ? 160.174 156.931 211.688 1.00 58.89  ? 193 LEU A CD1 1 
ATOM   1343  C  CD2 . LEU A 1 193 ? 162.328 157.225 212.896 1.00 58.89  ? 193 LEU A CD2 1 
ATOM   1344  N  N   . GLN A 1 194 ? 159.793 154.247 216.876 1.00 65.64  ? 194 GLN A N   1 
ATOM   1345  C  CA  . GLN A 1 194 ? 158.814 154.322 217.957 1.00 65.64  ? 194 GLN A CA  1 
ATOM   1346  C  C   . GLN A 1 194 ? 159.460 154.684 219.290 1.00 65.64  ? 194 GLN A C   1 
ATOM   1347  O  O   . GLN A 1 194 ? 158.770 154.784 220.310 1.00 65.64  ? 194 GLN A O   1 
ATOM   1348  C  CB  . GLN A 1 194 ? 158.056 152.999 218.067 1.00 65.64  ? 194 GLN A CB  1 
ATOM   1349  C  CG  . GLN A 1 194 ? 158.918 151.804 218.444 1.00 65.64  ? 194 GLN A CG  1 
ATOM   1350  C  CD  . GLN A 1 194 ? 159.060 151.632 219.944 1.00 65.64  ? 194 GLN A CD  1 
ATOM   1351  O  OE1 . GLN A 1 194 ? 158.160 151.978 220.708 1.00 65.64  ? 194 GLN A OE1 1 
ATOM   1352  N  NE2 . GLN A 1 194 ? 160.198 151.100 220.373 1.00 65.64  ? 194 GLN A NE2 1 
ATOM   1353  N  N   . ASN A 1 195 ? 160.775 154.885 219.309 1.00 68.99  ? 195 ASN A N   1 
ATOM   1354  C  CA  . ASN A 1 195 ? 161.475 155.226 220.539 1.00 68.99  ? 195 ASN A CA  1 
ATOM   1355  C  C   . ASN A 1 195 ? 162.518 156.320 220.355 1.00 68.99  ? 195 ASN A C   1 
ATOM   1356  O  O   . ASN A 1 195 ? 163.476 156.375 221.133 1.00 68.99  ? 195 ASN A O   1 
ATOM   1357  C  CB  . ASN A 1 195 ? 162.133 153.974 221.133 1.00 68.99  ? 195 ASN A CB  1 
ATOM   1358  C  CG  . ASN A 1 195 ? 163.149 153.338 220.197 1.00 68.99  ? 195 ASN A CG  1 
ATOM   1359  O  OD1 . ASN A 1 195 ? 163.456 153.869 219.130 1.00 68.99  ? 195 ASN A OD1 1 
ATOM   1360  N  ND2 . ASN A 1 195 ? 163.674 152.187 220.599 1.00 68.99  ? 195 ASN A ND2 1 
ATOM   1361  N  N   . THR A 1 196 ? 162.359 157.188 219.360 1.00 70.73  ? 196 THR A N   1 
ATOM   1362  C  CA  . THR A 1 196 ? 163.356 158.219 219.115 1.00 70.73  ? 196 THR A CA  1 
ATOM   1363  C  C   . THR A 1 196 ? 163.038 159.446 219.966 1.00 70.73  ? 196 THR A C   1 
ATOM   1364  O  O   . THR A 1 196 ? 163.010 159.377 221.197 1.00 70.73  ? 196 THR A O   1 
ATOM   1365  C  CB  . THR A 1 196 ? 163.393 158.577 217.626 1.00 70.73  ? 196 THR A CB  1 
ATOM   1366  O  OG1 . THR A 1 196 ? 163.397 157.370 216.856 1.00 70.73  ? 196 THR A OG1 1 
ATOM   1367  C  CG2 . THR A 1 196 ? 164.677 159.334 217.281 1.00 70.73  ? 196 THR A CG2 1 
ATOM   1368  N  N   . GLU A 1 197 ? 162.783 160.574 219.300 1.00 74.44  ? 197 GLU A N   1 
ATOM   1369  C  CA  . GLU A 1 197 ? 162.372 161.782 220.005 1.00 74.44  ? 197 GLU A CA  1 
ATOM   1370  C  C   . GLU A 1 197 ? 161.593 162.711 219.087 1.00 74.44  ? 197 GLU A C   1 
ATOM   1371  O  O   . GLU A 1 197 ? 160.745 163.478 219.556 1.00 74.44  ? 197 GLU A O   1 
ATOM   1372  C  CB  . GLU A 1 197 ? 163.587 162.501 220.592 1.00 74.44  ? 197 GLU A CB  1 
ATOM   1373  C  CG  . GLU A 1 197 ? 164.555 163.055 219.563 1.00 74.44  ? 197 GLU A CG  1 
ATOM   1374  C  CD  . GLU A 1 197 ? 165.752 163.733 220.198 1.00 74.44  ? 197 GLU A CD  1 
ATOM   1375  O  OE1 . GLU A 1 197 ? 165.836 163.750 221.444 1.00 74.44  ? 197 GLU A OE1 1 
ATOM   1376  O  OE2 . GLU A 1 197 ? 166.609 164.251 219.452 1.00 74.44  ? 197 GLU A OE2 1 
ATOM   1377  N  N   . GLU A 1 198 ? 161.870 162.661 217.782 1.00 65.57  ? 198 GLU A N   1 
ATOM   1378  C  CA  . GLU A 1 198 ? 161.002 163.325 216.818 1.00 65.57  ? 198 GLU A CA  1 
ATOM   1379  C  C   . GLU A 1 198 ? 159.623 162.681 216.809 1.00 65.57  ? 198 GLU A C   1 
ATOM   1380  O  O   . GLU A 1 198 ? 158.609 163.366 216.631 1.00 65.57  ? 198 GLU A O   1 
ATOM   1381  C  CB  . GLU A 1 198 ? 161.633 163.276 215.428 1.00 65.57  ? 198 GLU A CB  1 
ATOM   1382  C  CG  . GLU A 1 198 ? 162.909 164.089 215.295 1.00 65.57  ? 198 GLU A CG  1 
ATOM   1383  C  CD  . GLU A 1 198 ? 163.542 163.957 213.924 1.00 65.57  ? 198 GLU A CD  1 
ATOM   1384  O  OE1 . GLU A 1 198 ? 163.065 163.125 213.125 1.00 65.57  ? 198 GLU A OE1 1 
ATOM   1385  O  OE2 . GLU A 1 198 ? 164.518 164.685 213.645 1.00 65.57  ? 198 GLU A OE2 1 
ATOM   1386  N  N   . PHE A 1 199 ? 159.571 161.362 217.006 1.00 64.79  ? 199 PHE A N   1 
ATOM   1387  C  CA  . PHE A 1 199 ? 158.300 160.668 217.160 1.00 64.79  ? 199 PHE A CA  1 
ATOM   1388  C  C   . PHE A 1 199 ? 157.675 160.932 218.522 1.00 64.79  ? 199 PHE A C   1 
ATOM   1389  O  O   . PHE A 1 199 ? 156.489 160.644 218.717 1.00 64.79  ? 199 PHE A O   1 
ATOM   1390  C  CB  . PHE A 1 199 ? 158.509 159.167 216.953 1.00 64.79  ? 199 PHE A CB  1 
ATOM   1391  C  CG  . PHE A 1 199 ? 157.241 158.365 216.957 1.00 64.79  ? 199 PHE A CG  1 
ATOM   1392  C  CD1 . PHE A 1 199 ? 156.409 158.357 215.852 1.00 64.79  ? 199 PHE A CD1 1 
ATOM   1393  C  CD2 . PHE A 1 199 ? 156.886 157.610 218.060 1.00 64.79  ? 199 PHE A CD2 1 
ATOM   1394  C  CE1 . PHE A 1 199 ? 155.245 157.616 215.848 1.00 64.79  ? 199 PHE A CE1 1 
ATOM   1395  C  CE2 . PHE A 1 199 ? 155.721 156.868 218.061 1.00 64.79  ? 199 PHE A CE2 1 
ATOM   1396  C  CZ  . PHE A 1 199 ? 154.900 156.872 216.952 1.00 64.79  ? 199 PHE A CZ  1 
ATOM   1397  N  N   . LEU A 1 200 ? 158.443 161.485 219.464 1.00 76.09  ? 200 LEU A N   1 
ATOM   1398  C  CA  . LEU A 1 200 ? 157.914 161.716 220.804 1.00 76.09  ? 200 LEU A CA  1 
ATOM   1399  C  C   . LEU A 1 200 ? 157.005 162.939 220.831 1.00 76.09  ? 200 LEU A C   1 
ATOM   1400  O  O   . LEU A 1 200 ? 155.830 162.836 221.202 1.00 76.09  ? 200 LEU A O   1 
ATOM   1401  C  CB  . LEU A 1 200 ? 159.065 161.865 221.801 1.00 76.09  ? 200 LEU A CB  1 
ATOM   1402  C  CG  . LEU A 1 200 ? 158.755 161.795 223.301 1.00 76.09  ? 200 LEU A CG  1 
ATOM   1403  C  CD1 . LEU A 1 200 ? 159.963 161.266 224.060 1.00 76.09  ? 200 LEU A CD1 1 
ATOM   1404  C  CD2 . LEU A 1 200 ? 158.323 163.140 223.871 1.00 76.09  ? 200 LEU A CD2 1 
ATOM   1405  N  N   . HIS A 1 201 ? 157.527 164.103 220.442 1.00 71.57  ? 201 HIS A N   1 
ATOM   1406  C  CA  . HIS A 1 201 ? 156.755 165.339 220.404 1.00 71.57  ? 201 HIS A CA  1 
ATOM   1407  C  C   . HIS A 1 201 ? 155.971 165.490 219.105 1.00 71.57  ? 201 HIS A C   1 
ATOM   1408  O  O   . HIS A 1 201 ? 155.886 166.593 218.553 1.00 71.57  ? 201 HIS A O   1 
ATOM   1409  C  CB  . HIS A 1 201 ? 157.674 166.543 220.611 1.00 71.57  ? 201 HIS A CB  1 
ATOM   1410  C  CG  . HIS A 1 201 ? 158.334 166.577 221.953 1.00 71.57  ? 201 HIS A CG  1 
ATOM   1411  N  ND1 . HIS A 1 201 ? 159.554 165.986 222.197 1.00 71.57  ? 201 HIS A ND1 1 
ATOM   1412  C  CD2 . HIS A 1 201 ? 157.942 167.129 223.127 1.00 71.57  ? 201 HIS A CD2 1 
ATOM   1413  C  CE1 . HIS A 1 201 ? 159.889 166.175 223.461 1.00 71.57  ? 201 HIS A CE1 1 
ATOM   1414  N  NE2 . HIS A 1 201 ? 158.927 166.864 224.048 1.00 71.57  ? 201 HIS A NE2 1 
ATOM   1415  N  N   . LEU A 1 202 ? 155.390 164.405 218.610 1.00 63.13  ? 202 LEU A N   1 
ATOM   1416  C  CA  . LEU A 1 202 ? 154.719 164.430 217.317 1.00 63.13  ? 202 LEU A CA  1 
ATOM   1417  C  C   . LEU A 1 202 ? 153.258 164.832 217.491 1.00 63.13  ? 202 LEU A C   1 
ATOM   1418  O  O   . LEU A 1 202 ? 152.559 164.251 218.327 1.00 63.13  ? 202 LEU A O   1 
ATOM   1419  C  CB  . LEU A 1 202 ? 154.813 163.064 216.644 1.00 63.13  ? 202 LEU A CB  1 
ATOM   1420  C  CG  . LEU A 1 202 ? 154.266 162.936 215.223 1.00 63.13  ? 202 LEU A CG  1 
ATOM   1421  C  CD1 . LEU A 1 202 ? 155.039 163.834 214.285 1.00 63.13  ? 202 LEU A CD1 1 
ATOM   1422  C  CD2 . LEU A 1 202 ? 154.340 161.496 214.752 1.00 63.13  ? 202 LEU A CD2 1 
ATOM   1423  N  N   . PRO A 1 203 ? 152.767 165.823 216.735 1.00 60.20  ? 203 PRO A N   1 
ATOM   1424  C  CA  . PRO A 1 203 ? 151.342 166.177 216.806 1.00 60.20  ? 203 PRO A CA  1 
ATOM   1425  C  C   . PRO A 1 203 ? 150.431 165.024 216.416 1.00 60.20  ? 203 PRO A C   1 
ATOM   1426  O  O   . PRO A 1 203 ? 150.860 164.075 215.753 1.00 60.20  ? 203 PRO A O   1 
ATOM   1427  C  CB  . PRO A 1 203 ? 151.222 167.345 215.819 1.00 60.20  ? 203 PRO A CB  1 
ATOM   1428  C  CG  . PRO A 1 203 ? 152.592 167.927 215.763 1.00 60.20  ? 203 PRO A CG  1 
ATOM   1429  C  CD  . PRO A 1 203 ? 153.526 166.763 215.893 1.00 60.20  ? 203 PRO A CD  1 
ATOM   1430  N  N   . HIS A 1 204 ? 149.162 165.104 216.821 1.00 62.80  ? 204 HIS A N   1 
ATOM   1431  C  CA  . HIS A 1 204 ? 148.241 163.994 216.600 1.00 62.80  ? 204 HIS A CA  1 
ATOM   1432  C  C   . HIS A 1 204 ? 147.851 163.865 215.133 1.00 62.80  ? 204 HIS A C   1 
ATOM   1433  O  O   . HIS A 1 204 ? 147.623 162.752 214.644 1.00 62.80  ? 204 HIS A O   1 
ATOM   1434  C  CB  . HIS A 1 204 ? 146.998 164.169 217.470 1.00 62.80  ? 204 HIS A CB  1 
ATOM   1435  C  CG  . HIS A 1 204 ? 146.030 163.035 217.368 1.00 62.80  ? 204 HIS A CG  1 
ATOM   1436  N  ND1 . HIS A 1 204 ? 145.036 162.991 216.415 1.00 62.80  ? 204 HIS A ND1 1 
ATOM   1437  C  CD2 . HIS A 1 204 ? 145.910 161.897 218.092 1.00 62.80  ? 204 HIS A CD2 1 
ATOM   1438  C  CE1 . HIS A 1 204 ? 144.339 161.878 216.561 1.00 62.80  ? 204 HIS A CE1 1 
ATOM   1439  N  NE2 . HIS A 1 204 ? 144.851 161.196 217.569 1.00 62.80  ? 204 HIS A NE2 1 
ATOM   1440  N  N   . ARG A 1 205 ? 147.760 164.988 214.418 1.00 52.27  ? 205 ARG A N   1 
ATOM   1441  C  CA  . ARG A 1 205 ? 147.350 164.940 213.018 1.00 52.27  ? 205 ARG A CA  1 
ATOM   1442  C  C   . ARG A 1 205 ? 148.370 164.196 212.164 1.00 52.27  ? 205 ARG A C   1 
ATOM   1443  O  O   . ARG A 1 205 ? 148.000 163.378 211.311 1.00 52.27  ? 205 ARG A O   1 
ATOM   1444  C  CB  . ARG A 1 205 ? 147.131 166.360 212.496 1.00 52.27  ? 205 ARG A CB  1 
ATOM   1445  C  CG  . ARG A 1 205 ? 146.728 166.443 211.037 1.00 52.27  ? 205 ARG A CG  1 
ATOM   1446  C  CD  . ARG A 1 205 ? 146.434 167.882 210.644 1.00 52.27  ? 205 ARG A CD  1 
ATOM   1447  N  NE  . ARG A 1 205 ? 147.581 168.760 210.858 1.00 52.27  ? 205 ARG A NE  1 
ATOM   1448  C  CZ  . ARG A 1 205 ? 148.586 168.905 210.002 1.00 52.27  ? 205 ARG A CZ  1 
ATOM   1449  N  NH1 . ARG A 1 205 ? 148.596 168.228 208.862 1.00 52.27  ? 205 ARG A NH1 1 
ATOM   1450  N  NH2 . ARG A 1 205 ? 149.584 169.730 210.287 1.00 52.27  ? 205 ARG A NH2 1 
ATOM   1451  N  N   . LEU A 1 206 ? 149.660 164.456 212.387 1.00 50.29  ? 206 LEU A N   1 
ATOM   1452  C  CA  . LEU A 1 206 ? 150.693 163.758 211.630 1.00 50.29  ? 206 LEU A CA  1 
ATOM   1453  C  C   . LEU A 1 206 ? 150.666 162.262 211.913 1.00 50.29  ? 206 LEU A C   1 
ATOM   1454  O  O   . LEU A 1 206 ? 150.786 161.447 210.991 1.00 50.29  ? 206 LEU A O   1 
ATOM   1455  C  CB  . LEU A 1 206 ? 152.068 164.341 211.955 1.00 50.29  ? 206 LEU A CB  1 
ATOM   1456  C  CG  . LEU A 1 206 ? 152.280 165.801 211.553 1.00 50.29  ? 206 LEU A CG  1 
ATOM   1457  C  CD1 . LEU A 1 206 ? 153.642 166.298 212.007 1.00 50.29  ? 206 LEU A CD1 1 
ATOM   1458  C  CD2 . LEU A 1 206 ? 152.109 165.976 210.055 1.00 50.29  ? 206 LEU A CD2 1 
ATOM   1459  N  N   . LEU A 1 207 ? 150.499 161.882 213.182 1.00 53.11  ? 207 LEU A N   1 
ATOM   1460  C  CA  . LEU A 1 207 ? 150.455 160.465 213.526 1.00 53.11  ? 207 LEU A CA  1 
ATOM   1461  C  C   . LEU A 1 207 ? 149.243 159.785 212.905 1.00 53.11  ? 207 LEU A C   1 
ATOM   1462  O  O   . LEU A 1 207 ? 149.340 158.652 212.417 1.00 53.11  ? 207 LEU A O   1 
ATOM   1463  C  CB  . LEU A 1 207 ? 150.446 160.293 215.043 1.00 53.11  ? 207 LEU A CB  1 
ATOM   1464  C  CG  . LEU A 1 207 ? 150.482 158.844 215.525 1.00 53.11  ? 207 LEU A CG  1 
ATOM   1465  C  CD1 . LEU A 1 207 ? 151.774 158.175 215.101 1.00 53.11  ? 207 LEU A CD1 1 
ATOM   1466  C  CD2 . LEU A 1 207 ? 150.319 158.784 217.023 1.00 53.11  ? 207 LEU A CD2 1 
ATOM   1467  N  N   . THR A 1 208 ? 148.092 160.461 212.914 1.00 54.72  ? 208 THR A N   1 
ATOM   1468  C  CA  . THR A 1 208 ? 146.913 159.912 212.253 1.00 54.72  ? 208 THR A CA  1 
ATOM   1469  C  C   . THR A 1 208 ? 147.153 159.744 210.759 1.00 54.72  ? 208 THR A C   1 
ATOM   1470  O  O   . THR A 1 208 ? 146.705 158.763 210.155 1.00 54.72  ? 208 THR A O   1 
ATOM   1471  C  CB  . THR A 1 208 ? 145.701 160.808 212.507 1.00 54.72  ? 208 THR A CB  1 
ATOM   1472  O  OG1 . THR A 1 208 ? 145.441 160.870 213.914 1.00 54.72  ? 208 THR A OG1 1 
ATOM   1473  C  CG2 . THR A 1 208 ? 144.471 160.266 211.795 1.00 54.72  ? 208 THR A CG2 1 
ATOM   1474  N  N   . ASP A 1 209 ? 147.874 160.685 210.145 1.00 51.21  ? 209 ASP A N   1 
ATOM   1475  C  CA  . ASP A 1 209 ? 148.213 160.534 208.734 1.00 51.21  ? 209 ASP A CA  1 
ATOM   1476  C  C   . ASP A 1 209 ? 149.185 159.383 208.507 1.00 51.21  ? 209 ASP A C   1 
ATOM   1477  O  O   . ASP A 1 209 ? 149.168 158.763 207.438 1.00 51.21  ? 209 ASP A O   1 
ATOM   1478  C  CB  . ASP A 1 209 ? 148.796 161.838 208.194 1.00 51.21  ? 209 ASP A CB  1 
ATOM   1479  C  CG  . ASP A 1 209 ? 147.762 162.936 208.101 1.00 51.21  ? 209 ASP A CG  1 
ATOM   1480  O  OD1 . ASP A 1 209 ? 146.573 162.614 207.899 1.00 51.21  ? 209 ASP A OD1 1 
ATOM   1481  O  OD2 . ASP A 1 209 ? 148.135 164.120 208.233 1.00 51.21  ? 209 ASP A OD2 1 
ATOM   1482  N  N   . ILE A 1 210 ? 150.030 159.079 209.493 1.00 47.60  ? 210 ILE A N   1 
ATOM   1483  C  CA  . ILE A 1 210 ? 150.995 157.994 209.336 1.00 47.60  ? 210 ILE A CA  1 
ATOM   1484  C  C   . ILE A 1 210 ? 150.306 156.640 209.455 1.00 47.60  ? 210 ILE A C   1 
ATOM   1485  O  O   . ILE A 1 210 ? 150.471 155.766 208.597 1.00 47.60  ? 210 ILE A O   1 
ATOM   1486  C  CB  . ILE A 1 210 ? 152.135 158.130 210.361 1.00 47.60  ? 210 ILE A CB  1 
ATOM   1487  C  CG1 . ILE A 1 210 ? 152.986 159.362 210.061 1.00 47.60  ? 210 ILE A CG1 1 
ATOM   1488  C  CG2 . ILE A 1 210 ? 152.989 156.876 210.378 1.00 47.60  ? 210 ILE A CG2 1 
ATOM   1489  C  CD1 . ILE A 1 210 ? 153.989 159.685 211.146 1.00 47.60  ? 210 ILE A CD1 1 
ATOM   1490  N  N   . ILE A 1 211 ? 149.524 156.446 210.514 1.00 53.80  ? 211 ILE A N   1 
ATOM   1491  C  CA  . ILE A 1 211 ? 149.031 155.110 210.830 1.00 53.80  ? 211 ILE A CA  1 
ATOM   1492  C  C   . ILE A 1 211 ? 147.782 154.734 210.035 1.00 53.80  ? 211 ILE A C   1 
ATOM   1493  O  O   . ILE A 1 211 ? 147.535 153.546 209.807 1.00 53.80  ? 211 ILE A O   1 
ATOM   1494  C  CB  . ILE A 1 211 ? 148.768 154.984 212.338 1.00 53.80  ? 211 ILE A CB  1 
ATOM   1495  C  CG1 . ILE A 1 211 ? 147.634 155.916 212.760 1.00 53.80  ? 211 ILE A CG1 1 
ATOM   1496  C  CG2 . ILE A 1 211 ? 150.030 155.302 213.119 1.00 53.80  ? 211 ILE A CG2 1 
ATOM   1497  C  CD1 . ILE A 1 211 ? 147.120 155.655 214.152 1.00 53.80  ? 211 ILE A CD1 1 
ATOM   1498  N  N   . SER A 1 212 ? 146.989 155.710 209.604 1.00 58.16  ? 212 SER A N   1 
ATOM   1499  C  CA  . SER A 1 212 ? 145.694 155.428 208.984 1.00 58.16  ? 212 SER A CA  1 
ATOM   1500  C  C   . SER A 1 212 ? 145.782 155.373 207.463 1.00 58.16  ? 212 SER A C   1 
ATOM   1501  O  O   . SER A 1 212 ? 144.852 155.757 206.755 1.00 58.16  ? 212 SER A O   1 
ATOM   1502  C  CB  . SER A 1 212 ? 144.669 156.463 209.431 1.00 58.16  ? 212 SER A CB  1 
ATOM   1503  O  OG  . SER A 1 212 ? 143.415 156.233 208.815 1.00 58.16  ? 212 SER A OG  1 
ATOM   1504  N  N   . ASP A 1 213 ? 146.906 154.884 206.942 1.00 61.24  ? 213 ASP A N   1 
ATOM   1505  C  CA  . ASP A 1 213 ? 147.056 154.760 205.498 1.00 61.24  ? 213 ASP A CA  1 
ATOM   1506  C  C   . ASP A 1 213 ? 147.509 153.380 205.043 1.00 61.24  ? 213 ASP A C   1 
ATOM   1507  O  O   . ASP A 1 213 ? 147.371 153.077 203.854 1.00 61.24  ? 213 ASP A O   1 
ATOM   1508  C  CB  . ASP A 1 213 ? 148.042 155.814 204.971 1.00 61.24  ? 213 ASP A CB  1 
ATOM   1509  C  CG  . ASP A 1 213 ? 148.029 155.921 203.458 1.00 61.24  ? 213 ASP A CG  1 
ATOM   1510  O  OD1 . ASP A 1 213 ? 147.057 156.482 202.911 1.00 61.24  ? 213 ASP A OD1 1 
ATOM   1511  O  OD2 . ASP A 1 213 ? 148.988 155.446 202.816 1.00 61.24  ? 213 ASP A OD2 1 
ATOM   1512  N  N   . GLY A 1 214 ? 148.030 152.535 205.928 1.00 57.17  ? 214 GLY A N   1 
ATOM   1513  C  CA  . GLY A 1 214 ? 148.433 151.198 205.539 1.00 57.17  ? 214 GLY A CA  1 
ATOM   1514  C  C   . GLY A 1 214 ? 149.781 150.790 206.090 1.00 57.17  ? 214 GLY A C   1 
ATOM   1515  O  O   . GLY A 1 214 ? 150.719 150.534 205.329 1.00 57.17  ? 214 GLY A O   1 
ATOM   1516  N  N   . VAL A 1 215 ? 149.892 150.721 207.412 1.00 59.53  ? 215 VAL A N   1 
ATOM   1517  C  CA  . VAL A 1 215 ? 151.169 150.336 208.020 1.00 59.53  ? 215 VAL A CA  1 
ATOM   1518  C  C   . VAL A 1 215 ? 151.329 148.823 207.936 1.00 59.53  ? 215 VAL A C   1 
ATOM   1519  O  O   . VAL A 1 215 ? 150.425 148.081 208.366 1.00 59.53  ? 215 VAL A O   1 
ATOM   1520  C  CB  . VAL A 1 215 ? 151.238 150.812 209.480 1.00 59.53  ? 215 VAL A CB  1 
ATOM   1521  C  CG1 . VAL A 1 215 ? 152.530 150.343 210.126 1.00 59.53  ? 215 VAL A CG1 1 
ATOM   1522  C  CG2 . VAL A 1 215 ? 151.117 152.322 209.551 1.00 59.53  ? 215 VAL A CG2 1 
ATOM   1523  N  N   . PRO A 1 216 ? 152.430 148.310 207.392 1.00 68.93  ? 216 PRO A N   1 
ATOM   1524  C  CA  . PRO A 1 216 ? 152.644 146.860 207.395 1.00 68.93  ? 216 PRO A CA  1 
ATOM   1525  C  C   . PRO A 1 216 ? 152.765 146.323 208.811 1.00 68.93  ? 216 PRO A C   1 
ATOM   1526  O  O   . PRO A 1 216 ? 153.264 146.995 209.717 1.00 68.93  ? 216 PRO A O   1 
ATOM   1527  C  CB  . PRO A 1 216 ? 153.957 146.694 206.622 1.00 68.93  ? 216 PRO A CB  1 
ATOM   1528  C  CG  . PRO A 1 216 ? 154.056 147.925 205.782 1.00 68.93  ? 216 PRO A CG  1 
ATOM   1529  C  CD  . PRO A 1 216 ? 153.464 149.017 206.620 1.00 68.93  ? 216 PRO A CD  1 
ATOM   1530  N  N   . CYS A 1 217 ? 152.298 145.088 208.992 1.00 78.06  ? 217 CYS A N   1 
ATOM   1531  C  CA  . CYS A 1 217 ? 152.240 144.475 210.314 1.00 78.06  ? 217 CYS A CA  1 
ATOM   1532  C  C   . CYS A 1 217 ? 153.626 144.146 210.856 1.00 78.06  ? 217 CYS A C   1 
ATOM   1533  O  O   . CYS A 1 217 ? 153.782 143.896 212.055 1.00 78.06  ? 217 CYS A O   1 
ATOM   1534  C  CB  . CYS A 1 217 ? 151.380 143.211 210.273 1.00 78.06  ? 217 CYS A CB  1 
ATOM   1535  S  SG  . CYS A 1 217 ? 149.630 143.511 209.937 1.00 78.06  ? 217 CYS A SG  1 
ATOM   1536  N  N   . SER A 1 218 ? 154.636 144.144 209.987 1.00 78.31  ? 218 SER A N   1 
ATOM   1537  C  CA  . SER A 1 218 ? 155.996 143.798 210.383 1.00 78.31  ? 218 SER A CA  1 
ATOM   1538  C  C   . SER A 1 218 ? 156.627 144.759 211.381 1.00 78.31  ? 218 SER A C   1 
ATOM   1539  O  O   . SER A 1 218 ? 157.660 144.409 211.964 1.00 78.31  ? 218 SER A O   1 
ATOM   1540  C  CB  . SER A 1 218 ? 156.908 143.709 209.149 1.00 78.31  ? 218 SER A CB  1 
ATOM   1541  O  OG  . SER A 1 218 ? 156.504 142.658 208.289 1.00 78.31  ? 218 SER A OG  1 
ATOM   1542  N  N   . GLN A 1 219 ? 156.056 145.943 211.602 1.00 75.07  ? 219 GLN A N   1 
ATOM   1543  C  CA  . GLN A 1 219 ? 156.628 146.927 212.512 1.00 75.07  ? 219 GLN A CA  1 
ATOM   1544  C  C   . GLN A 1 219 ? 155.809 147.090 213.789 1.00 75.07  ? 219 GLN A C   1 
ATOM   1545  O  O   . GLN A 1 219 ? 156.122 147.956 214.613 1.00 75.07  ? 219 GLN A O   1 
ATOM   1546  C  CB  . GLN A 1 219 ? 156.783 148.275 211.806 1.00 75.07  ? 219 GLN A CB  1 
ATOM   1547  C  CG  . GLN A 1 219 ? 157.836 148.289 210.712 1.00 75.07  ? 219 GLN A CG  1 
ATOM   1548  C  CD  . GLN A 1 219 ? 157.316 147.751 209.398 1.00 75.07  ? 219 GLN A CD  1 
ATOM   1549  O  OE1 . GLN A 1 219 ? 156.107 147.657 209.190 1.00 75.07  ? 219 GLN A OE1 1 
ATOM   1550  N  NE2 . GLN A 1 219 ? 158.227 147.395 208.501 1.00 75.07  ? 219 GLN A NE2 1 
ATOM   1551  N  N   . ASN A 1 220 ? 154.772 146.268 213.970 1.00 79.78  ? 220 ASN A N   1 
ATOM   1552  C  CA  . ASN A 1 220 ? 153.896 146.314 215.137 1.00 79.78  ? 220 ASN A CA  1 
ATOM   1553  C  C   . ASN A 1 220 ? 153.325 147.713 215.331 1.00 79.78  ? 220 ASN A C   1 
ATOM   1554  O  O   . ASN A 1 220 ? 153.791 148.460 216.201 1.00 79.78  ? 220 ASN A O   1 
ATOM   1555  C  CB  . ASN A 1 220 ? 154.642 145.867 216.396 1.00 79.78  ? 220 ASN A CB  1 
ATOM   1556  C  CG  . ASN A 1 220 ? 154.926 144.379 216.409 1.00 79.78  ? 220 ASN A CG  1 
ATOM   1557  O  OD1 . ASN A 1 220 ? 154.076 143.570 216.037 1.00 79.78  ? 220 ASN A OD1 1 
ATOM   1558  N  ND2 . ASN A 1 220 ? 156.125 144.009 216.840 1.00 79.78  ? 220 ASN A ND2 1 
ATOM   1559  N  N   . PRO A 1 221 ? 152.320 148.106 214.544 1.00 78.36  ? 221 PRO A N   1 
ATOM   1560  C  CA  . PRO A 1 221 ? 151.740 149.445 214.718 1.00 78.36  ? 221 PRO A CA  1 
ATOM   1561  C  C   . PRO A 1 221 ? 150.942 149.596 215.999 1.00 78.36  ? 221 PRO A C   1 
ATOM   1562  O  O   . PRO A 1 221 ? 150.950 150.686 216.584 1.00 78.36  ? 221 PRO A O   1 
ATOM   1563  C  CB  . PRO A 1 221 ? 150.847 149.603 213.482 1.00 78.36  ? 221 PRO A CB  1 
ATOM   1564  C  CG  . PRO A 1 221 ? 150.477 148.207 213.116 1.00 78.36  ? 221 PRO A CG  1 
ATOM   1565  C  CD  . PRO A 1 221 ? 151.672 147.358 213.453 1.00 78.36  ? 221 PRO A CD  1 
ATOM   1566  N  N   . THR A 1 222 ? 150.261 148.542 216.455 1.00 80.82  ? 222 THR A N   1 
ATOM   1567  C  CA  . THR A 1 222 ? 149.442 148.617 217.659 1.00 80.82  ? 222 THR A CA  1 
ATOM   1568  C  C   . THR A 1 222 ? 150.240 149.012 218.894 1.00 80.82  ? 222 THR A C   1 
ATOM   1569  O  O   . THR A 1 222 ? 149.774 149.849 219.674 1.00 80.82  ? 222 THR A O   1 
ATOM   1570  C  CB  . THR A 1 222 ? 148.747 147.274 217.903 1.00 80.82  ? 222 THR A CB  1 
ATOM   1571  O  OG1 . THR A 1 222 ? 147.915 146.954 216.782 1.00 80.82  ? 222 THR A OG1 1 
ATOM   1572  C  CG2 . THR A 1 222 ? 147.891 147.333 219.159 1.00 80.82  ? 222 THR A CG2 1 
ATOM   1573  N  N   . GLU A 1 223 ? 151.426 148.439 219.084 1.00 83.63  ? 223 GLU A N   1 
ATOM   1574  C  CA  . GLU A 1 223 ? 152.276 148.773 220.220 1.00 83.63  ? 223 GLU A CA  1 
ATOM   1575  C  C   . GLU A 1 223 ? 152.882 150.166 220.123 1.00 83.63  ? 223 GLU A C   1 
ATOM   1576  O  O   . GLU A 1 223 ? 153.072 150.819 221.155 1.00 83.63  ? 223 GLU A O   1 
ATOM   1577  C  CB  . GLU A 1 223 ? 153.396 147.734 220.355 1.00 83.63  ? 223 GLU A CB  1 
ATOM   1578  C  CG  . GLU A 1 223 ? 154.198 147.813 221.647 1.00 83.63  ? 223 GLU A CG  1 
ATOM   1579  C  CD  . GLU A 1 223 ? 155.363 148.777 221.557 1.00 83.63  ? 223 GLU A CD  1 
ATOM   1580  O  OE1 . GLU A 1 223 ? 155.887 148.973 220.441 1.00 83.63  ? 223 GLU A OE1 1 
ATOM   1581  O  OE2 . GLU A 1 223 ? 155.756 149.337 222.602 1.00 83.63  ? 223 GLU A OE2 1 
ATOM   1582  N  N   . ALA A 1 224 ? 153.178 150.639 218.910 1.00 77.45  ? 224 ALA A N   1 
ATOM   1583  C  CA  . ALA A 1 224 ? 153.788 151.956 218.759 1.00 77.45  ? 224 ALA A CA  1 
ATOM   1584  C  C   . ALA A 1 224 ? 152.798 153.068 219.081 1.00 77.45  ? 224 ALA A C   1 
ATOM   1585  O  O   . ALA A 1 224 ? 153.199 154.183 219.434 1.00 77.45  ? 224 ALA A O   1 
ATOM   1586  C  CB  . ALA A 1 224 ? 154.340 152.122 217.344 1.00 77.45  ? 224 ALA A CB  1 
ATOM   1587  N  N   . ILE A 1 225 ? 151.499 152.787 218.958 1.00 77.61  ? 225 ILE A N   1 
ATOM   1588  C  CA  . ILE A 1 225 ? 150.490 153.783 219.310 1.00 77.61  ? 225 ILE A CA  1 
ATOM   1589  C  C   . ILE A 1 225 ? 150.508 154.042 220.809 1.00 77.61  ? 225 ILE A C   1 
ATOM   1590  O  O   . ILE A 1 225 ? 150.692 155.179 221.261 1.00 77.61  ? 225 ILE A O   1 
ATOM   1591  C  CB  . ILE A 1 225 ? 149.098 153.335 218.833 1.00 77.61  ? 225 ILE A CB  1 
ATOM   1592  C  CG1 . ILE A 1 225 ? 149.103 153.116 217.323 1.00 77.61  ? 225 ILE A CG1 1 
ATOM   1593  C  CG2 . ILE A 1 225 ? 148.049 154.363 219.220 1.00 77.61  ? 225 ILE A CG2 1 
ATOM   1594  C  CD1 . ILE A 1 225 ? 149.477 154.344 216.546 1.00 77.61  ? 225 ILE A CD1 1 
ATOM   1595  N  N   . GLU A 1 226 ? 150.321 152.986 221.604 1.00 85.29  ? 226 GLU A N   1 
ATOM   1596  C  CA  . GLU A 1 226 ? 150.353 153.133 223.055 1.00 85.29  ? 226 GLU A CA  1 
ATOM   1597  C  C   . GLU A 1 226 ? 151.726 153.595 223.527 1.00 85.29  ? 226 GLU A C   1 
ATOM   1598  O  O   . GLU A 1 226 ? 151.841 154.310 224.531 1.00 85.29  ? 226 GLU A O   1 
ATOM   1599  C  CB  . GLU A 1 226 ? 149.954 151.811 223.713 1.00 85.29  ? 226 GLU A CB  1 
ATOM   1600  C  CG  . GLU A 1 226 ? 149.639 151.895 225.197 1.00 85.29  ? 226 GLU A CG  1 
ATOM   1601  C  CD  . GLU A 1 226 ? 150.865 151.733 226.070 1.00 85.29  ? 226 GLU A CD  1 
ATOM   1602  O  OE1 . GLU A 1 226 ? 151.822 151.059 225.636 1.00 85.29  ? 226 GLU A OE1 1 
ATOM   1603  O  OE2 . GLU A 1 226 ? 150.867 152.272 227.195 1.00 85.29  ? 226 GLU A OE2 1 
ATOM   1604  N  N   . ALA A 1 227 ? 152.781 153.205 222.804 1.00 80.07  ? 227 ALA A N   1 
ATOM   1605  C  CA  . ALA A 1 227 ? 154.111 153.728 223.096 1.00 80.07  ? 227 ALA A CA  1 
ATOM   1606  C  C   . ALA A 1 227 ? 154.160 155.237 222.897 1.00 80.07  ? 227 ALA A C   1 
ATOM   1607  O  O   . ALA A 1 227 ? 154.809 155.954 223.668 1.00 80.07  ? 227 ALA A O   1 
ATOM   1608  C  CB  . ALA A 1 227 ? 155.153 153.035 222.220 1.00 80.07  ? 227 ALA A CB  1 
ATOM   1609  N  N   . TRP A 1 228 ? 153.481 155.738 221.864 1.00 79.97  ? 228 TRP A N   1 
ATOM   1610  C  CA  . TRP A 1 228 ? 153.352 157.181 221.696 1.00 79.97  ? 228 TRP A CA  1 
ATOM   1611  C  C   . TRP A 1 228 ? 152.520 157.790 222.816 1.00 79.97  ? 228 TRP A C   1 
ATOM   1612  O  O   . TRP A 1 228 ? 152.756 158.933 223.222 1.00 79.97  ? 228 TRP A O   1 
ATOM   1613  C  CB  . TRP A 1 228 ? 152.716 157.501 220.346 1.00 79.97  ? 228 TRP A CB  1 
ATOM   1614  C  CG  . TRP A 1 228 ? 152.541 158.964 220.113 1.00 79.97  ? 228 TRP A CG  1 
ATOM   1615  C  CD1 . TRP A 1 228 ? 153.520 159.874 219.855 1.00 79.97  ? 228 TRP A CD1 1 
ATOM   1616  C  CD2 . TRP A 1 228 ? 151.314 159.699 220.170 1.00 79.97  ? 228 TRP A CD2 1 
ATOM   1617  N  NE1 . TRP A 1 228 ? 152.977 161.127 219.714 1.00 79.97  ? 228 TRP A NE1 1 
ATOM   1618  C  CE2 . TRP A 1 228 ? 151.624 161.047 219.906 1.00 79.97  ? 228 TRP A CE2 1 
ATOM   1619  C  CE3 . TRP A 1 228 ? 149.982 159.347 220.404 1.00 79.97  ? 228 TRP A CE3 1 
ATOM   1620  C  CZ2 . TRP A 1 228 ? 150.652 162.043 219.874 1.00 79.97  ? 228 TRP A CZ2 1 
ATOM   1621  C  CZ3 . TRP A 1 228 ? 149.019 160.337 220.367 1.00 79.97  ? 228 TRP A CZ3 1 
ATOM   1622  C  CH2 . TRP A 1 228 ? 149.359 161.669 220.106 1.00 79.97  ? 228 TRP A CH2 1 
ATOM   1623  N  N   . ILE A 1 229 ? 151.539 157.041 223.320 1.00 84.58  ? 229 ILE A N   1 
ATOM   1624  C  CA  . ILE A 1 229 ? 150.631 157.578 224.328 1.00 84.58  ? 229 ILE A CA  1 
ATOM   1625  C  C   . ILE A 1 229 ? 151.350 157.763 225.656 1.00 84.58  ? 229 ILE A C   1 
ATOM   1626  O  O   . ILE A 1 229 ? 151.159 158.774 226.341 1.00 84.58  ? 229 ILE A O   1 
ATOM   1627  C  CB  . ILE A 1 229 ? 149.399 156.668 224.467 1.00 84.58  ? 229 ILE A CB  1 
ATOM   1628  C  CG1 . ILE A 1 229 ? 148.615 156.643 223.156 1.00 84.58  ? 229 ILE A CG1 1 
ATOM   1629  C  CG2 . ILE A 1 229 ? 148.513 157.139 225.608 1.00 84.58  ? 229 ILE A CG2 1 
ATOM   1630  C  CD1 . ILE A 1 229 ? 147.582 155.550 223.088 1.00 84.58  ? 229 ILE A CD1 1 
ATOM   1631  N  N   . ASN A 1 230 ? 152.202 156.806 226.037 1.00 86.13  ? 230 ASN A N   1 
ATOM   1632  C  CA  . ASN A 1 230 ? 152.904 156.912 227.313 1.00 86.13  ? 230 ASN A CA  1 
ATOM   1633  C  C   . ASN A 1 230 ? 153.851 158.105 227.369 1.00 86.13  ? 230 ASN A C   1 
ATOM   1634  O  O   . ASN A 1 230 ? 154.374 158.415 228.444 1.00 86.13  ? 230 ASN A O   1 
ATOM   1635  C  CB  . ASN A 1 230 ? 153.684 155.631 227.603 1.00 86.13  ? 230 ASN A CB  1 
ATOM   1636  C  CG  . ASN A 1 230 ? 152.782 154.469 227.955 1.00 86.13  ? 230 ASN A CG  1 
ATOM   1637  O  OD1 . ASN A 1 230 ? 151.793 154.630 228.669 1.00 86.13  ? 230 ASN A OD1 1 
ATOM   1638  N  ND2 . ASN A 1 230 ? 153.126 153.286 227.465 1.00 86.13  ? 230 ASN A ND2 1 
ATOM   1639  N  N   . PHE A 1 231 ? 154.084 158.779 226.241 1.00 84.48  ? 231 PHE A N   1 
ATOM   1640  C  CA  . PHE A 1 231 ? 154.966 159.941 226.243 1.00 84.48  ? 231 PHE A CA  1 
ATOM   1641  C  C   . PHE A 1 231 ? 154.347 161.105 227.010 1.00 84.48  ? 231 PHE A C   1 
ATOM   1642  O  O   . PHE A 1 231 ? 155.060 162.010 227.460 1.00 84.48  ? 231 PHE A O   1 
ATOM   1643  C  CB  . PHE A 1 231 ? 155.289 160.351 224.807 1.00 84.48  ? 231 PHE A CB  1 
ATOM   1644  C  CG  . PHE A 1 231 ? 156.175 159.376 224.081 1.00 84.48  ? 231 PHE A CG  1 
ATOM   1645  C  CD1 . PHE A 1 231 ? 156.929 158.447 224.779 1.00 84.48  ? 231 PHE A CD1 1 
ATOM   1646  C  CD2 . PHE A 1 231 ? 156.240 159.379 222.698 1.00 84.48  ? 231 PHE A CD2 1 
ATOM   1647  C  CE1 . PHE A 1 231 ? 157.743 157.550 224.110 1.00 84.48  ? 231 PHE A CE1 1 
ATOM   1648  C  CE2 . PHE A 1 231 ? 157.052 158.485 222.024 1.00 84.48  ? 231 PHE A CE2 1 
ATOM   1649  C  CZ  . PHE A 1 231 ? 157.803 157.570 222.731 1.00 84.48  ? 231 PHE A CZ  1 
ATOM   1650  N  N   . ASN A 1 232 ? 153.023 161.099 227.171 1.00 93.47  ? 232 ASN A N   1 
ATOM   1651  C  CA  . ASN A 1 232 ? 152.298 162.150 227.890 1.00 93.47  ? 232 ASN A CA  1 
ATOM   1652  C  C   . ASN A 1 232 ? 151.251 161.461 228.761 1.00 93.47  ? 232 ASN A C   1 
ATOM   1653  O  O   . ASN A 1 232 ? 150.866 161.986 229.811 1.00 93.47  ? 232 ASN A O   1 
ATOM   1654  C  CB  . ASN A 1 232 ? 151.673 163.145 226.918 1.00 93.47  ? 232 ASN A CB  1 
ATOM   1655  C  CG  . ASN A 1 232 ? 151.180 164.405 227.603 1.00 93.47  ? 232 ASN A CG  1 
ATOM   1656  O  OD1 . ASN A 1 232 ? 151.269 164.543 228.822 1.00 93.47  ? 232 ASN A OD1 1 
ATOM   1657  N  ND2 . ASN A 1 232 ? 150.667 165.341 226.813 1.00 93.47  ? 232 ASN A ND2 1 
ATOM   1658  N  N   . LYS A 1 233 ? 150.786 160.293 228.306 1.00 95.82  ? 233 LYS A N   1 
ATOM   1659  C  CA  . LYS A 1 233 ? 149.894 159.457 229.108 1.00 95.82  ? 233 LYS A CA  1 
ATOM   1660  C  C   . LYS A 1 233 ? 148.579 160.162 229.419 1.00 95.82  ? 233 LYS A C   1 
ATOM   1661  O  O   . LYS A 1 233 ? 147.530 159.801 228.874 1.00 95.82  ? 233 LYS A O   1 
ATOM   1662  C  CB  . LYS A 1 233 ? 150.591 159.022 230.399 1.00 95.82  ? 233 LYS A CB  1 
ATOM   1663  C  CG  . LYS A 1 233 ? 149.741 158.131 231.289 1.00 95.82  ? 233 LYS A CG  1 
ATOM   1664  C  CD  . LYS A 1 233 ? 149.500 156.776 230.644 1.00 95.82  ? 233 LYS A CD  1 
ATOM   1665  C  CE  . LYS A 1 233 ? 148.772 155.834 231.589 1.00 95.82  ? 233 LYS A CE  1 
ATOM   1666  N  NZ  . LYS A 1 233 ? 147.383 156.290 231.872 1.00 95.82  ? 233 LYS A NZ  1 
ATOM   1667  N  N   . GLU A 1 234 ? 148.612 161.166 230.292 1.00 99.93  ? 234 GLU A N   1 
ATOM   1668  C  CA  . GLU A 1 234 ? 147.388 161.755 230.821 1.00 99.93  ? 234 GLU A CA  1 
ATOM   1669  C  C   . GLU A 1 234 ? 146.622 162.595 229.806 1.00 99.93  ? 234 GLU A C   1 
ATOM   1670  O  O   . GLU A 1 234 ? 145.389 162.648 229.871 1.00 99.93  ? 234 GLU A O   1 
ATOM   1671  C  CB  . GLU A 1 234 ? 147.712 162.603 232.057 1.00 99.93  ? 234 GLU A CB  1 
ATOM   1672  C  CG  . GLU A 1 234 ? 148.706 163.733 231.818 1.00 99.93  ? 234 GLU A CG  1 
ATOM   1673  C  CD  . GLU A 1 234 ? 148.042 165.019 231.366 1.00 99.93  ? 234 GLU A CD  1 
ATOM   1674  O  OE1 . GLU A 1 234 ? 146.820 165.164 231.578 1.00 99.93  ? 234 GLU A OE1 1 
ATOM   1675  O  OE2 . GLU A 1 234 ? 148.742 165.884 230.802 1.00 99.93  ? 234 GLU A OE2 1 
ATOM   1676  N  N   . GLU A 1 235 ? 147.309 163.248 228.870 1.00 97.17  ? 235 GLU A N   1 
ATOM   1677  C  CA  . GLU A 1 235 ? 146.639 164.195 227.985 1.00 97.17  ? 235 GLU A CA  1 
ATOM   1678  C  C   . GLU A 1 235 ? 146.199 163.560 226.670 1.00 97.17  ? 235 GLU A C   1 
ATOM   1679  O  O   . GLU A 1 235 ? 145.004 163.529 226.364 1.00 97.17  ? 235 GLU A O   1 
ATOM   1680  C  CB  . GLU A 1 235 ? 147.552 165.393 227.712 1.00 97.17  ? 235 GLU A CB  1 
ATOM   1681  C  CG  . GLU A 1 235 ? 146.905 166.478 226.871 1.00 97.17  ? 235 GLU A CG  1 
ATOM   1682  C  CD  . GLU A 1 235 ? 147.810 167.676 226.672 1.00 97.17  ? 235 GLU A CD  1 
ATOM   1683  O  OE1 . GLU A 1 235 ? 148.955 167.647 227.170 1.00 97.17  ? 235 GLU A OE1 1 
ATOM   1684  O  OE2 . GLU A 1 235 ? 147.377 168.647 226.017 1.00 97.17  ? 235 GLU A OE2 1 
ATOM   1685  N  N   . ARG A 1 236 ? 147.146 163.050 225.886 1.00 89.72  ? 236 ARG A N   1 
ATOM   1686  C  CA  . ARG A 1 236 ? 146.860 162.468 224.581 1.00 89.72  ? 236 ARG A CA  1 
ATOM   1687  C  C   . ARG A 1 236 ? 146.173 161.108 224.665 1.00 89.72  ? 236 ARG A C   1 
ATOM   1688  O  O   . ARG A 1 236 ? 146.350 160.280 223.765 1.00 89.72  ? 236 ARG A O   1 
ATOM   1689  C  CB  . ARG A 1 236 ? 148.154 162.361 223.770 1.00 89.72  ? 236 ARG A CB  1 
ATOM   1690  C  CG  . ARG A 1 236 ? 149.203 161.450 224.389 1.00 89.72  ? 236 ARG A CG  1 
ATOM   1691  C  CD  . ARG A 1 236 ? 150.523 161.532 223.638 1.00 89.72  ? 236 ARG A CD  1 
ATOM   1692  N  NE  . ARG A 1 236 ? 151.127 162.855 223.763 1.00 89.72  ? 236 ARG A NE  1 
ATOM   1693  C  CZ  . ARG A 1 236 ? 152.245 163.231 223.152 1.00 89.72  ? 236 ARG A CZ  1 
ATOM   1694  N  NH1 . ARG A 1 236 ? 152.901 162.379 222.379 1.00 89.72  ? 236 ARG A NH1 1 
ATOM   1695  N  NH2 . ARG A 1 236 ? 152.718 164.457 223.325 1.00 89.72  ? 236 ARG A NH2 1 
ATOM   1696  N  N   . GLU A 1 237 ? 145.381 160.868 225.710 1.00 92.78  ? 237 GLU A N   1 
ATOM   1697  C  CA  . GLU A 1 237 ? 144.679 159.604 225.877 1.00 92.78  ? 237 GLU A CA  1 
ATOM   1698  C  C   . GLU A 1 237 ? 143.179 159.735 225.638 1.00 92.78  ? 237 GLU A C   1 
ATOM   1699  O  O   . GLU A 1 237 ? 142.490 158.713 225.539 1.00 92.78  ? 237 GLU A O   1 
ATOM   1700  C  CB  . GLU A 1 237 ? 144.953 159.053 227.281 1.00 92.78  ? 237 GLU A CB  1 
ATOM   1701  C  CG  . GLU A 1 237 ? 144.475 157.633 227.538 1.00 92.78  ? 237 GLU A CG  1 
ATOM   1702  C  CD  . GLU A 1 237 ? 144.868 157.132 228.913 1.00 92.78  ? 237 GLU A CD  1 
ATOM   1703  O  OE1 . GLU A 1 237 ? 145.488 157.906 229.672 1.00 92.78  ? 237 GLU A OE1 1 
ATOM   1704  O  OE2 . GLU A 1 237 ? 144.561 155.965 229.234 1.00 92.78  ? 237 GLU A OE2 1 
ATOM   1705  N  N   . ALA A 1 238 ? 142.663 160.962 225.527 1.00 90.44  ? 238 ALA A N   1 
ATOM   1706  C  CA  . ALA A 1 238 ? 141.235 161.151 225.290 1.00 90.44  ? 238 ALA A CA  1 
ATOM   1707  C  C   . ALA A 1 238 ? 140.802 160.528 223.969 1.00 90.44  ? 238 ALA A C   1 
ATOM   1708  O  O   . ALA A 1 238 ? 139.679 160.024 223.852 1.00 90.44  ? 238 ALA A O   1 
ATOM   1709  C  CB  . ALA A 1 238 ? 140.891 162.639 225.320 1.00 90.44  ? 238 ALA A CB  1 
ATOM   1710  N  N   . PHE A 1 239 ? 141.675 160.550 222.966 1.00 89.41  ? 239 PHE A N   1 
ATOM   1711  C  CA  . PHE A 1 239 ? 141.396 159.942 221.673 1.00 89.41  ? 239 PHE A CA  1 
ATOM   1712  C  C   . PHE A 1 239 ? 142.114 158.606 221.505 1.00 89.41  ? 239 PHE A C   1 
ATOM   1713  O  O   . PHE A 1 239 ? 141.971 157.963 220.460 1.00 89.41  ? 239 PHE A O   1 
ATOM   1714  C  CB  . PHE A 1 239 ? 141.792 160.912 220.553 1.00 89.41  ? 239 PHE A CB  1 
ATOM   1715  C  CG  . PHE A 1 239 ? 141.260 160.538 219.196 1.00 89.41  ? 239 PHE A CG  1 
ATOM   1716  C  CD1 . PHE A 1 239 ? 139.935 160.778 218.873 1.00 89.41  ? 239 PHE A CD1 1 
ATOM   1717  C  CD2 . PHE A 1 239 ? 142.082 159.964 218.242 1.00 89.41  ? 239 PHE A CD2 1 
ATOM   1718  C  CE1 . PHE A 1 239 ? 139.439 160.448 217.624 1.00 89.41  ? 239 PHE A CE1 1 
ATOM   1719  C  CE2 . PHE A 1 239 ? 141.590 159.627 216.992 1.00 89.41  ? 239 PHE A CE2 1 
ATOM   1720  C  CZ  . PHE A 1 239 ? 140.267 159.868 216.685 1.00 89.41  ? 239 PHE A CZ  1 
ATOM   1721  N  N   . ALA A 1 240 ? 142.860 158.174 222.529 1.00 91.37  ? 240 ALA A N   1 
ATOM   1722  C  CA  . ALA A 1 240 ? 143.695 156.979 222.429 1.00 91.37  ? 240 ALA A CA  1 
ATOM   1723  C  C   . ALA A 1 240 ? 142.924 155.774 221.912 1.00 91.37  ? 240 ALA A C   1 
ATOM   1724  O  O   . ALA A 1 240 ? 143.326 155.166 220.912 1.00 91.37  ? 240 ALA A O   1 
ATOM   1725  C  CB  . ALA A 1 240 ? 144.310 156.658 223.790 1.00 91.37  ? 240 ALA A CB  1 
ATOM   1726  N  N   . GLU A 1 241 ? 141.826 155.407 222.577 1.00 93.40  ? 241 GLU A N   1 
ATOM   1727  C  CA  . GLU A 1 241 ? 141.033 154.274 222.112 1.00 93.40  ? 241 GLU A CA  1 
ATOM   1728  C  C   . GLU A 1 241 ? 140.516 154.511 220.700 1.00 93.40  ? 241 GLU A C   1 
ATOM   1729  O  O   . GLU A 1 241 ? 140.503 153.592 219.873 1.00 93.40  ? 241 GLU A O   1 
ATOM   1730  C  CB  . GLU A 1 241 ? 139.874 154.011 223.075 1.00 93.40  ? 241 GLU A CB  1 
ATOM   1731  C  CG  . GLU A 1 241 ? 139.142 152.697 222.829 1.00 93.40  ? 241 GLU A CG  1 
ATOM   1732  C  CD  . GLU A 1 241 ? 138.073 152.811 221.759 1.00 93.40  ? 241 GLU A CD  1 
ATOM   1733  O  OE1 . GLU A 1 241 ? 137.509 153.913 221.597 1.00 93.40  ? 241 GLU A OE1 1 
ATOM   1734  O  OE2 . GLU A 1 241 ? 137.804 151.800 221.076 1.00 93.40  ? 241 GLU A OE2 1 
ATOM   1735  N  N   . SER A 1 242 ? 140.094 155.741 220.400 1.00 87.44  ? 242 SER A N   1 
ATOM   1736  C  CA  . SER A 1 242 ? 139.635 156.042 219.050 1.00 87.44  ? 242 SER A CA  1 
ATOM   1737  C  C   . SER A 1 242 ? 140.803 156.181 218.084 1.00 87.44  ? 242 SER A C   1 
ATOM   1738  O  O   . SER A 1 242 ? 140.605 156.142 216.864 1.00 87.44  ? 242 SER A O   1 
ATOM   1739  C  CB  . SER A 1 242 ? 138.787 157.311 219.049 1.00 87.44  ? 242 SER A CB  1 
ATOM   1740  O  OG  . SER A 1 242 ? 138.332 157.607 217.741 1.00 87.44  ? 242 SER A OG  1 
ATOM   1741  N  N   . LEU A 1 243 ? 142.020 156.348 218.604 1.00 83.07  ? 243 LEU A N   1 
ATOM   1742  C  CA  . LEU A 1 243 ? 143.197 156.336 217.743 1.00 83.07  ? 243 LEU A CA  1 
ATOM   1743  C  C   . LEU A 1 243 ? 143.579 154.910 217.370 1.00 83.07  ? 243 LEU A C   1 
ATOM   1744  O  O   . LEU A 1 243 ? 144.210 154.678 216.332 1.00 83.07  ? 243 LEU A O   1 
ATOM   1745  C  CB  . LEU A 1 243 ? 144.359 157.049 218.434 1.00 83.07  ? 243 LEU A CB  1 
ATOM   1746  C  CG  . LEU A 1 243 ? 145.655 157.214 217.640 1.00 83.07  ? 243 LEU A CG  1 
ATOM   1747  C  CD1 . LEU A 1 243 ? 145.413 158.057 216.401 1.00 83.07  ? 243 LEU A CD1 1 
ATOM   1748  C  CD2 . LEU A 1 243 ? 146.739 157.835 218.507 1.00 83.07  ? 243 LEU A CD2 1 
ATOM   1749  N  N   . ARG A 1 244 ? 143.196 153.940 218.204 1.00 86.25  ? 244 ARG A N   1 
ATOM   1750  C  CA  . ARG A 1 244 ? 143.467 152.541 217.891 1.00 86.25  ? 244 ARG A CA  1 
ATOM   1751  C  C   . ARG A 1 244 ? 142.404 151.977 216.955 1.00 86.25  ? 244 ARG A C   1 
ATOM   1752  O  O   . ARG A 1 244 ? 142.552 150.872 216.421 1.00 86.25  ? 244 ARG A O   1 
ATOM   1753  C  CB  . ARG A 1 244 ? 143.551 151.733 219.188 1.00 86.25  ? 244 ARG A CB  1 
ATOM   1754  C  CG  . ARG A 1 244 ? 144.002 150.291 219.026 1.00 86.25  ? 244 ARG A CG  1 
ATOM   1755  C  CD  . ARG A 1 244 ? 144.133 149.604 220.374 1.00 86.25  ? 244 ARG A CD  1 
ATOM   1756  N  NE  . ARG A 1 244 ? 145.204 150.189 221.175 1.00 86.25  ? 244 ARG A NE  1 
ATOM   1757  C  CZ  . ARG A 1 244 ? 145.012 150.880 222.293 1.00 86.25  ? 244 ARG A CZ  1 
ATOM   1758  N  NH1 . ARG A 1 244 ? 143.783 151.077 222.751 1.00 86.25  ? 244 ARG A NH1 1 
ATOM   1759  N  NH2 . ARG A 1 244 ? 146.049 151.375 222.954 1.00 86.25  ? 244 ARG A NH2 1 
ATOM   1760  N  N   . THR A 1 245 ? 141.328 152.727 216.735 1.00 83.11  ? 245 THR A N   1 
ATOM   1761  C  CA  . THR A 1 245 ? 140.285 152.337 215.786 1.00 83.11  ? 245 THR A CA  1 
ATOM   1762  C  C   . THR A 1 245 ? 140.447 153.070 214.458 1.00 83.11  ? 245 THR A C   1 
ATOM   1763  O  O   . THR A 1 245 ? 139.555 153.077 213.611 1.00 83.11  ? 245 THR A O   1 
ATOM   1764  C  CB  . THR A 1 245 ? 138.910 152.597 216.388 1.00 83.11  ? 245 THR A CB  1 
ATOM   1765  O  OG1 . THR A 1 245 ? 138.754 154.000 216.636 1.00 83.11  ? 245 THR A OG1 1 
ATOM   1766  C  CG2 . THR A 1 245 ? 138.748 151.836 217.695 1.00 83.11  ? 245 THR A CG2 1 
ATOM   1767  N  N   . SER A 1 246 ? 141.607 153.699 214.272 1.00 77.56  ? 246 SER A N   1 
ATOM   1768  C  CA  . SER A 1 246 ? 141.856 154.503 213.079 1.00 77.56  ? 246 SER A CA  1 
ATOM   1769  C  C   . SER A 1 246 ? 142.910 153.936 212.141 1.00 77.56  ? 246 SER A C   1 
ATOM   1770  O  O   . SER A 1 246 ? 142.856 154.242 210.945 1.00 77.56  ? 246 SER A O   1 
ATOM   1771  C  CB  . SER A 1 246 ? 142.268 155.926 213.474 1.00 77.56  ? 246 SER A CB  1 
ATOM   1772  O  OG  . SER A 1 246 ? 143.516 155.924 214.145 1.00 77.56  ? 246 SER A OG  1 
ATOM   1773  N  N   . LEU A 1 247 ? 143.858 153.131 212.613 1.00 70.43  ? 247 LEU A N   1 
ATOM   1774  C  CA  . LEU A 1 247 ? 144.916 152.626 211.749 1.00 70.43  ? 247 LEU A CA  1 
ATOM   1775  C  C   . LEU A 1 247 ? 144.361 151.604 210.769 1.00 70.43  ? 247 LEU A C   1 
ATOM   1776  O  O   . LEU A 1 247 ? 143.240 151.113 210.926 1.00 70.43  ? 247 LEU A O   1 
ATOM   1777  C  CB  . LEU A 1 247 ? 146.041 151.992 212.570 1.00 70.43  ? 247 LEU A CB  1 
ATOM   1778  C  CG  . LEU A 1 247 ? 145.832 150.579 213.121 1.00 70.43  ? 247 LEU A CG  1 
ATOM   1779  C  CD1 . LEU A 1 247 ? 147.165 149.971 213.515 1.00 70.43  ? 247 LEU A CD1 1 
ATOM   1780  C  CD2 . LEU A 1 247 ? 144.889 150.581 214.304 1.00 70.43  ? 247 LEU A CD2 1 
ATOM   1781  N  N   . LYS A 1 248 ? 145.158 151.286 209.750 1.00 67.96  ? 248 LYS A N   1 
ATOM   1782  C  CA  . LYS A 1 248 ? 144.792 150.276 208.761 1.00 67.96  ? 248 LYS A CA  1 
ATOM   1783  C  C   . LYS A 1 248 ? 145.949 149.287 208.657 1.00 67.96  ? 248 LYS A C   1 
ATOM   1784  O  O   . LYS A 1 248 ? 146.792 149.356 207.763 1.00 67.96  ? 248 LYS A O   1 
ATOM   1785  C  CB  . LYS A 1 248 ? 144.464 150.922 207.419 1.00 67.96  ? 248 LYS A CB  1 
ATOM   1786  C  CG  . LYS A 1 248 ? 143.988 149.939 206.360 1.00 67.96  ? 248 LYS A CG  1 
ATOM   1787  C  CD  . LYS A 1 248 ? 143.555 150.650 205.090 1.00 67.96  ? 248 LYS A CD  1 
ATOM   1788  C  CE  . LYS A 1 248 ? 144.753 151.169 204.315 1.00 67.96  ? 248 LYS A CE  1 
ATOM   1789  N  NZ  . LYS A 1 248 ? 144.358 151.762 203.008 1.00 67.96  ? 248 LYS A NZ  1 
ATOM   1790  N  N   . GLU A 1 249 ? 145.987 148.359 209.610 1.00 75.49  ? 249 GLU A N   1 
ATOM   1791  C  CA  . GLU A 1 249 ? 147.001 147.315 209.598 1.00 75.49  ? 249 GLU A CA  1 
ATOM   1792  C  C   . GLU A 1 249 ? 146.830 146.429 208.370 1.00 75.49  ? 249 GLU A C   1 
ATOM   1793  O  O   . GLU A 1 249 ? 145.721 145.995 208.045 1.00 75.49  ? 249 GLU A O   1 
ATOM   1794  C  CB  . GLU A 1 249 ? 146.922 146.494 210.887 1.00 75.49  ? 249 GLU A CB  1 
ATOM   1795  C  CG  . GLU A 1 249 ? 145.592 145.790 211.115 1.00 75.49  ? 249 GLU A CG  1 
ATOM   1796  C  CD  . GLU A 1 249 ? 145.526 145.094 212.460 1.00 75.49  ? 249 GLU A CD  1 
ATOM   1797  O  OE1 . GLU A 1 249 ? 146.516 145.169 213.218 1.00 75.49  ? 249 GLU A OE1 1 
ATOM   1798  O  OE2 . GLU A 1 249 ? 144.482 144.478 212.762 1.00 75.49  ? 249 GLU A OE2 1 
ATOM   1799  N  N   . ILE A 1 250 ? 147.939 146.176 207.675 1.00 75.05  ? 250 ILE A N   1 
ATOM   1800  C  CA  . ILE A 1 250 ? 147.927 145.455 206.410 1.00 75.05  ? 250 ILE A CA  1 
ATOM   1801  C  C   . ILE A 1 250 ? 149.052 144.428 206.416 1.00 75.05  ? 250 ILE A C   1 
ATOM   1802  O  O   . ILE A 1 250 ? 150.116 144.637 207.002 1.00 75.05  ? 250 ILE A O   1 
ATOM   1803  C  CB  . ILE A 1 250 ? 148.062 146.418 205.205 1.00 75.05  ? 250 ILE A CB  1 
ATOM   1804  C  CG1 . ILE A 1 250 ? 147.808 145.689 203.886 1.00 75.05  ? 250 ILE A CG1 1 
ATOM   1805  C  CG2 . ILE A 1 250 ? 149.424 147.098 205.202 1.00 75.05  ? 250 ILE A CG2 1 
ATOM   1806  C  CD1 . ILE A 1 250 ? 147.621 146.621 202.711 1.00 75.05  ? 250 ILE A CD1 1 
ATOM   1807  N  N   . GLY A 1 251 ? 148.794 143.295 205.766 1.00 82.04  ? 251 GLY A N   1 
ATOM   1808  C  CA  . GLY A 1 251 ? 149.792 142.253 205.683 1.00 82.04  ? 251 GLY A CA  1 
ATOM   1809  C  C   . GLY A 1 251 ? 150.974 142.649 204.819 1.00 82.04  ? 251 GLY A C   1 
ATOM   1810  O  O   . GLY A 1 251 ? 150.916 143.574 204.008 1.00 82.04  ? 251 GLY A O   1 
ATOM   1811  N  N   . GLU A 1 252 ? 152.073 141.923 205.003 1.00 80.82  ? 252 GLU A N   1 
ATOM   1812  C  CA  . GLU A 1 252 ? 153.286 142.208 204.253 1.00 80.82  ? 252 GLU A CA  1 
ATOM   1813  C  C   . GLU A 1 252 ? 153.216 141.591 202.861 1.00 80.82  ? 252 GLU A C   1 
ATOM   1814  O  O   . GLU A 1 252 ? 152.756 140.461 202.677 1.00 80.82  ? 252 GLU A O   1 
ATOM   1815  C  CB  . GLU A 1 252 ? 154.512 141.680 205.000 1.00 80.82  ? 252 GLU A CB  1 
ATOM   1816  C  CG  . GLU A 1 252 ? 155.838 141.977 204.313 1.00 80.82  ? 252 GLU A CG  1 
ATOM   1817  C  CD  . GLU A 1 252 ? 156.151 143.462 204.251 1.00 80.82  ? 252 GLU A CD  1 
ATOM   1818  O  OE1 . GLU A 1 252 ? 155.671 144.213 205.126 1.00 80.82  ? 252 GLU A OE1 1 
ATOM   1819  O  OE2 . GLU A 1 252 ? 156.875 143.878 203.322 1.00 80.82  ? 252 GLU A OE2 1 
ATOM   1820  N  N   . ASN A 1 253 ? 153.683 142.350 201.874 1.00 76.24  ? 253 ASN A N   1 
ATOM   1821  C  CA  . ASN A 1 253 ? 153.701 141.919 200.486 1.00 76.24  ? 253 ASN A CA  1 
ATOM   1822  C  C   . ASN A 1 253 ? 154.910 141.019 200.255 1.00 76.24  ? 253 ASN A C   1 
ATOM   1823  O  O   . ASN A 1 253 ? 155.195 140.119 201.051 1.00 76.24  ? 253 ASN A O   1 
ATOM   1824  C  CB  . ASN A 1 253 ? 153.734 143.130 199.543 1.00 76.24  ? 253 ASN A CB  1 
ATOM   1825  C  CG  . ASN A 1 253 ? 153.379 142.773 198.109 1.00 76.24  ? 253 ASN A CG  1 
ATOM   1826  O  OD1 . ASN A 1 253 ? 153.121 141.613 197.789 1.00 76.24  ? 253 ASN A OD1 1 
ATOM   1827  N  ND2 . ASN A 1 253 ? 153.369 143.775 197.236 1.00 76.24  ? 253 ASN A ND2 1 
ATOM   1828  N  N   . VAL A 1 254 ? 155.623 141.274 199.163 1.00 70.55  ? 254 VAL A N   1 
ATOM   1829  C  CA  . VAL A 1 254 ? 156.809 140.500 198.814 1.00 70.55  ? 254 VAL A CA  1 
ATOM   1830  C  C   . VAL A 1 254 ? 157.611 141.279 197.779 1.00 70.55  ? 254 VAL A C   1 
ATOM   1831  O  O   . VAL A 1 254 ? 157.043 141.974 196.928 1.00 70.55  ? 254 VAL A O   1 
ATOM   1832  C  CB  . VAL A 1 254 ? 156.415 139.106 198.299 1.00 70.55  ? 254 VAL A CB  1 
ATOM   1833  C  CG1 . VAL A 1 254 ? 155.611 139.215 197.021 1.00 70.55  ? 254 VAL A CG1 1 
ATOM   1834  C  CG2 . VAL A 1 254 ? 157.646 138.243 198.093 1.00 70.55  ? 254 VAL A CG2 1 
ATOM   1835  N  N   . HIS A 1 255 ? 158.935 141.181 197.860 1.00 66.05  ? 255 HIS A N   1 
ATOM   1836  C  CA  . HIS A 1 255 ? 159.831 141.976 197.035 1.00 66.05  ? 255 HIS A CA  1 
ATOM   1837  C  C   . HIS A 1 255 ? 160.776 141.072 196.258 1.00 66.05  ? 255 HIS A C   1 
ATOM   1838  O  O   . HIS A 1 255 ? 161.127 139.983 196.721 1.00 66.05  ? 255 HIS A O   1 
ATOM   1839  C  CB  . HIS A 1 255 ? 160.654 142.941 197.894 1.00 66.05  ? 255 HIS A CB  1 
ATOM   1840  C  CG  . HIS A 1 255 ? 159.830 143.924 198.664 1.00 66.05  ? 255 HIS A CG  1 
ATOM   1841  N  ND1 . HIS A 1 255 ? 159.348 143.659 199.927 1.00 66.05  ? 255 HIS A ND1 1 
ATOM   1842  C  CD2 . HIS A 1 255 ? 159.407 145.171 198.354 1.00 66.05  ? 255 HIS A CD2 1 
ATOM   1843  C  CE1 . HIS A 1 255 ? 158.660 144.700 200.361 1.00 66.05  ? 255 HIS A CE1 1 
ATOM   1844  N  NE2 . HIS A 1 255 ? 158.681 145.632 199.425 1.00 66.05  ? 255 HIS A NE2 1 
ATOM   1845  N  N   . ILE A 1 256 ? 161.171 141.532 195.071 1.00 52.03  ? 256 ILE A N   1 
ATOM   1846  C  CA  . ILE A 1 256 ? 162.297 140.984 194.319 1.00 52.03  ? 256 ILE A CA  1 
ATOM   1847  C  C   . ILE A 1 256 ? 162.121 139.493 194.051 1.00 52.03  ? 256 ILE A C   1 
ATOM   1848  O  O   . ILE A 1 256 ? 162.516 138.650 194.863 1.00 52.03  ? 256 ILE A O   1 
ATOM   1849  C  CB  . ILE A 1 256 ? 163.620 141.261 195.054 1.00 52.03  ? 256 ILE A CB  1 
ATOM   1850  C  CG1 . ILE A 1 256 ? 163.812 142.765 195.242 1.00 52.03  ? 256 ILE A CG1 1 
ATOM   1851  C  CG2 . ILE A 1 256 ? 164.794 140.712 194.274 1.00 52.03  ? 256 ILE A CG2 1 
ATOM   1852  C  CD1 . ILE A 1 256 ? 164.950 143.122 196.166 1.00 52.03  ? 256 ILE A CD1 1 
ATOM   1853  N  N   . TYR A 1 257 ? 161.534 139.161 192.905 1.00 52.03  ? 257 TYR A N   1 
ATOM   1854  C  CA  . TYR A 1 257 ? 161.394 137.786 192.446 1.00 52.03  ? 257 TYR A CA  1 
ATOM   1855  C  C   . TYR A 1 257 ? 162.638 137.385 191.668 1.00 52.03  ? 257 TYR A C   1 
ATOM   1856  O  O   . TYR A 1 257 ? 163.269 138.228 191.024 1.00 52.03  ? 257 TYR A O   1 
ATOM   1857  C  CB  . TYR A 1 257 ? 160.153 137.632 191.569 1.00 52.03  ? 257 TYR A CB  1 
ATOM   1858  C  CG  . TYR A 1 257 ? 158.851 137.617 192.330 1.00 52.03  ? 257 TYR A CG  1 
ATOM   1859  C  CD1 . TYR A 1 257 ? 158.811 137.295 193.677 1.00 52.03  ? 257 TYR A CD1 1 
ATOM   1860  C  CD2 . TYR A 1 257 ? 157.663 137.944 191.702 1.00 52.03  ? 257 TYR A CD2 1 
ATOM   1861  C  CE1 . TYR A 1 257 ? 157.615 137.280 194.368 1.00 52.03  ? 257 TYR A CE1 1 
ATOM   1862  C  CE2 . TYR A 1 257 ? 156.470 137.933 192.383 1.00 52.03  ? 257 TYR A CE2 1 
ATOM   1863  C  CZ  . TYR A 1 257 ? 156.449 137.602 193.713 1.00 52.03  ? 257 TYR A CZ  1 
ATOM   1864  O  OH  . TYR A 1 257 ? 155.249 137.596 194.382 1.00 52.03  ? 257 TYR A OH  1 
ATOM   1865  N  N   . LEU A 1 258 ? 162.990 136.104 191.731 1.00 50.06  ? 258 LEU A N   1 
ATOM   1866  C  CA  . LEU A 1 258 ? 164.154 135.566 191.036 1.00 50.06  ? 258 LEU A CA  1 
ATOM   1867  C  C   . LEU A 1 258 ? 163.752 134.306 190.282 1.00 50.06  ? 258 LEU A C   1 
ATOM   1868  O  O   . LEU A 1 258 ? 163.933 133.194 190.789 1.00 50.06  ? 258 LEU A O   1 
ATOM   1869  C  CB  . LEU A 1 258 ? 165.292 135.255 192.010 1.00 50.06  ? 258 LEU A CB  1 
ATOM   1870  C  CG  . LEU A 1 258 ? 166.232 136.375 192.460 1.00 50.06  ? 258 LEU A CG  1 
ATOM   1871  C  CD1 . LEU A 1 258 ? 165.522 137.326 193.381 1.00 50.06  ? 258 LEU A CD1 1 
ATOM   1872  C  CD2 . LEU A 1 258 ? 167.454 135.802 193.151 1.00 50.06  ? 258 LEU A CD2 1 
ATOM   1873  N  N   . ILE A 1 259 ? 163.212 134.478 189.078 1.00 53.24  ? 259 ILE A N   1 
ATOM   1874  C  CA  . ILE A 1 259 ? 162.937 133.339 188.212 1.00 53.24  ? 259 ILE A CA  1 
ATOM   1875  C  C   . ILE A 1 259 ? 164.268 132.846 187.663 1.00 53.24  ? 259 ILE A C   1 
ATOM   1876  O  O   . ILE A 1 259 ? 164.752 133.338 186.637 1.00 53.24  ? 259 ILE A O   1 
ATOM   1877  C  CB  . ILE A 1 259 ? 161.957 133.702 187.082 1.00 53.24  ? 259 ILE A CB  1 
ATOM   1878  C  CG1 . ILE A 1 259 ? 160.609 134.130 187.659 1.00 53.24  ? 259 ILE A CG1 1 
ATOM   1879  C  CG2 . ILE A 1 259 ? 161.752 132.523 186.152 1.00 53.24  ? 259 ILE A CG2 1 
ATOM   1880  C  CD1 . ILE A 1 259 ? 159.668 134.692 186.631 1.00 53.24  ? 259 ILE A CD1 1 
ATOM   1881  N  N   . GLY A 1 260 ? 164.878 131.884 188.352 1.00 68.02  ? 260 GLY A N   1 
ATOM   1882  C  CA  . GLY A 1 260 ? 166.200 131.432 187.969 1.00 68.02  ? 260 GLY A CA  1 
ATOM   1883  C  C   . GLY A 1 260 ? 166.259 129.941 187.694 1.00 68.02  ? 260 GLY A C   1 
ATOM   1884  O  O   . GLY A 1 260 ? 165.504 129.144 188.250 1.00 68.02  ? 260 GLY A O   1 
ATOM   1885  N  N   . LYS A 1 261 ? 167.183 129.569 186.815 1.00 84.23  ? 261 LYS A N   1 
ATOM   1886  C  CA  . LYS A 1 261 ? 167.401 128.170 186.449 1.00 84.23  ? 261 LYS A CA  1 
ATOM   1887  C  C   . LYS A 1 261 ? 168.546 127.584 187.274 1.00 84.23  ? 261 LYS A C   1 
ATOM   1888  O  O   . LYS A 1 261 ? 169.724 127.875 187.060 1.00 84.23  ? 261 LYS A O   1 
ATOM   1889  C  CB  . LYS A 1 261 ? 167.670 128.055 184.950 1.00 84.23  ? 261 LYS A CB  1 
ATOM   1890  C  CG  . LYS A 1 261 ? 167.675 126.632 184.405 1.00 84.23  ? 261 LYS A CG  1 
ATOM   1891  C  CD  . LYS A 1 261 ? 169.073 126.031 184.368 1.00 84.23  ? 261 LYS A CD  1 
ATOM   1892  C  CE  . LYS A 1 261 ? 169.055 124.641 183.749 1.00 84.23  ? 261 LYS A CE  1 
ATOM   1893  N  NZ  . LYS A 1 261 ? 170.405 124.012 183.741 1.00 84.23  ? 261 LYS A NZ  1 
ATOM   1894  N  N   . GLU A 1 262 ? 168.178 126.744 188.237 1.00 90.62  ? 262 GLU A N   1 
ATOM   1895  C  CA  . GLU A 1 262 ? 169.171 126.143 189.116 1.00 90.62  ? 262 GLU A CA  1 
ATOM   1896  C  C   . GLU A 1 262 ? 169.200 124.631 188.925 1.00 90.62  ? 262 GLU A C   1 
ATOM   1897  O  O   . GLU A 1 262 ? 168.192 124.015 188.567 1.00 90.62  ? 262 GLU A O   1 
ATOM   1898  C  CB  . GLU A 1 262 ? 168.865 126.495 190.574 1.00 90.62  ? 262 GLU A CB  1 
ATOM   1899  C  CG  . GLU A 1 262 ? 169.989 126.196 191.557 1.00 90.62  ? 262 GLU A CG  1 
ATOM   1900  C  CD  . GLU A 1 262 ? 169.957 124.775 192.082 1.00 90.62  ? 262 GLU A CD  1 
ATOM   1901  O  OE1 . GLU A 1 262 ? 168.855 124.195 192.161 1.00 90.62  ? 262 GLU A OE1 1 
ATOM   1902  O  OE2 . GLU A 1 262 ? 171.035 124.238 192.414 1.00 90.62  ? 262 GLU A OE2 1 
ATOM   1903  N  N   . SER A 1 263 ? 170.376 124.041 189.155 1.00 93.28  ? 263 SER A N   1 
ATOM   1904  C  CA  . SER A 1 263 ? 170.610 122.603 189.048 1.00 93.28  ? 263 SER A CA  1 
ATOM   1905  C  C   . SER A 1 263 ? 170.424 122.108 187.618 1.00 93.28  ? 263 SER A C   1 
ATOM   1906  O  O   . SER A 1 263 ? 170.043 122.876 186.729 1.00 93.28  ? 263 SER A O   1 
ATOM   1907  C  CB  . SER A 1 263 ? 169.699 121.822 190.004 1.00 93.28  ? 263 SER A CB  1 
ATOM   1908  O  OG  . SER A 1 263 ? 168.339 121.903 189.615 1.00 93.28  ? 263 SER A OG  1 
ATOM   1909  N  N   . SER A 1 264 ? 170.706 120.826 187.387 1.00 100.10 ? 264 SER A N   1 
ATOM   1910  C  CA  . SER A 1 264 ? 170.578 120.245 186.057 1.00 100.10 ? 264 SER A CA  1 
ATOM   1911  C  C   . SER A 1 264 ? 169.119 120.226 185.623 1.00 100.10 ? 264 SER A C   1 
ATOM   1912  O  O   . SER A 1 264 ? 168.312 119.474 186.180 1.00 100.10 ? 264 SER A O   1 
ATOM   1913  C  CB  . SER A 1 264 ? 171.164 118.832 186.028 1.00 100.10 ? 264 SER A CB  1 
ATOM   1914  O  OG  . SER A 1 264 ? 172.558 118.856 186.279 1.00 100.10 ? 264 SER A OG  1 
ATOM   1915  N  N   . ARG A 1 265 ? 168.780 121.050 184.630 1.00 101.41 ? 265 ARG A N   1 
ATOM   1916  C  CA  . ARG A 1 265 ? 167.407 121.200 184.158 1.00 101.41 ? 265 ARG A CA  1 
ATOM   1917  C  C   . ARG A 1 265 ? 166.472 121.554 185.308 1.00 101.41 ? 265 ARG A C   1 
ATOM   1918  O  O   . ARG A 1 265 ? 166.618 122.614 185.925 1.00 101.41 ? 265 ARG A O   1 
ATOM   1919  C  CB  . ARG A 1 265 ? 166.932 119.926 183.453 1.00 101.41 ? 265 ARG A CB  1 
ATOM   1920  C  CG  . ARG A 1 265 ? 167.706 119.593 182.190 1.00 101.41 ? 265 ARG A CG  1 
ATOM   1921  C  CD  . ARG A 1 265 ? 167.418 120.605 181.093 1.00 101.41 ? 265 ARG A CD  1 
ATOM   1922  N  NE  . ARG A 1 265 ? 168.085 120.264 179.840 1.00 101.41 ? 265 ARG A NE  1 
ATOM   1923  C  CZ  . ARG A 1 265 ? 168.050 121.019 178.747 1.00 101.41 ? 265 ARG A CZ  1 
ATOM   1924  N  NH1 . ARG A 1 265 ? 167.377 122.161 178.750 1.00 101.41 ? 265 ARG A NH1 1 
ATOM   1925  N  NH2 . ARG A 1 265 ? 168.685 120.632 177.650 1.00 101.41 ? 265 ARG A NH2 1 
ATOM   1926  N  N   . THR A 1 266 ? 165.518 120.670 185.597 1.00 98.65  ? 266 THR A N   1 
ATOM   1927  C  CA  . THR A 1 266 ? 164.517 120.875 186.643 1.00 98.65  ? 266 THR A CA  1 
ATOM   1928  C  C   . THR A 1 266 ? 163.785 122.201 186.411 1.00 98.65  ? 266 THR A C   1 
ATOM   1929  O  O   . THR A 1 266 ? 163.406 122.922 187.336 1.00 98.65  ? 266 THR A O   1 
ATOM   1930  C  CB  . THR A 1 266 ? 165.166 120.805 188.033 1.00 98.65  ? 266 THR A CB  1 
ATOM   1931  O  OG1 . THR A 1 266 ? 165.993 119.638 188.106 1.00 98.65  ? 266 THR A OG1 1 
ATOM   1932  C  CG2 . THR A 1 266 ? 164.109 120.681 189.130 1.00 98.65  ? 266 THR A CG2 1 
ATOM   1933  N  N   . HIS A 1 267 ? 163.602 122.512 185.128 1.00 95.14  ? 267 HIS A N   1 
ATOM   1934  C  CA  . HIS A 1 267 ? 162.988 123.763 184.689 1.00 95.14  ? 267 HIS A CA  1 
ATOM   1935  C  C   . HIS A 1 267 ? 163.682 124.972 185.310 1.00 95.14  ? 267 HIS A C   1 
ATOM   1936  O  O   . HIS A 1 267 ? 164.887 125.158 185.149 1.00 95.14  ? 267 HIS A O   1 
ATOM   1937  C  CB  . HIS A 1 267 ? 161.495 123.776 185.024 1.00 95.14  ? 267 HIS A CB  1 
ATOM   1938  C  CG  . HIS A 1 267 ? 160.708 122.728 184.303 1.00 95.14  ? 267 HIS A CG  1 
ATOM   1939  N  ND1 . HIS A 1 267 ? 160.381 122.830 182.968 1.00 95.14  ? 267 HIS A ND1 1 
ATOM   1940  C  CD2 . HIS A 1 267 ? 160.184 121.554 184.730 1.00 95.14  ? 267 HIS A CD2 1 
ATOM   1941  C  CE1 . HIS A 1 267 ? 159.688 121.765 182.604 1.00 95.14  ? 267 HIS A CE1 1 
ATOM   1942  N  NE2 . HIS A 1 267 ? 159.555 120.976 183.654 1.00 95.14  ? 267 HIS A NE2 1 
ATOM   1943  N  N   . SER A 1 268 ? 162.914 125.791 186.025 1.00 79.75  ? 268 SER A N   1 
ATOM   1944  C  CA  . SER A 1 268 ? 163.468 126.957 186.699 1.00 79.75  ? 268 SER A CA  1 
ATOM   1945  C  C   . SER A 1 268 ? 162.919 127.059 188.114 1.00 79.75  ? 268 SER A C   1 
ATOM   1946  O  O   . SER A 1 268 ? 162.566 126.044 188.723 1.00 79.75  ? 268 SER A O   1 
ATOM   1947  C  CB  . SER A 1 268 ? 163.158 128.232 185.912 1.00 79.75  ? 268 SER A CB  1 
ATOM   1948  O  OG  . SER A 1 268 ? 161.768 128.501 185.912 1.00 79.75  ? 268 SER A OG  1 
ATOM   1949  N  N   . LEU A 1 269 ? 162.838 128.275 188.642 1.00 67.06  ? 269 LEU A N   1 
ATOM   1950  C  CA  . LEU A 1 269 ? 162.305 128.495 189.979 1.00 67.06  ? 269 LEU A CA  1 
ATOM   1951  C  C   . LEU A 1 269 ? 161.458 129.765 189.957 1.00 67.06  ? 269 LEU A C   1 
ATOM   1952  O  O   . LEU A 1 269 ? 161.103 130.268 188.885 1.00 67.06  ? 269 LEU A O   1 
ATOM   1953  C  CB  . LEU A 1 269 ? 163.445 128.570 191.009 1.00 67.06  ? 269 LEU A CB  1 
ATOM   1954  C  CG  . LEU A 1 269 ? 164.224 127.288 191.300 1.00 67.06  ? 269 LEU A CG  1 
ATOM   1955  C  CD1 . LEU A 1 269 ? 165.405 127.580 192.208 1.00 67.06  ? 269 LEU A CD1 1 
ATOM   1956  C  CD2 . LEU A 1 269 ? 163.315 126.249 191.930 1.00 67.06  ? 269 LEU A CD2 1 
ATOM   1957  N  N   . ALA A 1 270 ? 161.131 130.272 191.142 1.00 55.48  ? 270 ALA A N   1 
ATOM   1958  C  CA  . ALA A 1 270 ? 160.432 131.539 191.299 1.00 55.48  ? 270 ALA A CA  1 
ATOM   1959  C  C   . ALA A 1 270 ? 160.686 132.057 192.706 1.00 55.48  ? 270 ALA A C   1 
ATOM   1960  O  O   . ALA A 1 270 ? 159.746 132.383 193.438 1.00 55.48  ? 270 ALA A O   1 
ATOM   1961  C  CB  . ALA A 1 270 ? 158.935 131.380 191.032 1.00 55.48  ? 270 ALA A CB  1 
ATOM   1962  N  N   . VAL A 1 271 ? 161.963 132.126 193.087 1.00 54.74  ? 271 VAL A N   1 
ATOM   1963  C  CA  . VAL A 1 271 ? 162.325 132.453 194.460 1.00 54.74  ? 271 VAL A CA  1 
ATOM   1964  C  C   . VAL A 1 271 ? 161.928 133.887 194.771 1.00 54.74  ? 271 VAL A C   1 
ATOM   1965  O  O   . VAL A 1 271 ? 162.279 134.821 194.040 1.00 54.74  ? 271 VAL A O   1 
ATOM   1966  C  CB  . VAL A 1 271 ? 163.828 132.231 194.679 1.00 54.74  ? 271 VAL A CB  1 
ATOM   1967  C  CG1 . VAL A 1 271 ? 164.223 132.633 196.088 1.00 54.74  ? 271 VAL A CG1 1 
ATOM   1968  C  CG2 . VAL A 1 271 ? 164.196 130.784 194.404 1.00 54.74  ? 271 VAL A CG2 1 
ATOM   1969  N  N   . SER A 1 272 ? 161.192 134.065 195.862 1.00 59.30  ? 272 SER A N   1 
ATOM   1970  C  CA  . SER A 1 272 ? 160.771 135.379 196.340 1.00 59.30  ? 272 SER A CA  1 
ATOM   1971  C  C   . SER A 1 272 ? 161.730 135.775 197.458 1.00 59.30  ? 272 SER A C   1 
ATOM   1972  O  O   . SER A 1 272 ? 162.384 134.924 198.062 1.00 59.30  ? 272 SER A O   1 
ATOM   1973  C  CB  . SER A 1 272 ? 159.324 135.352 196.815 1.00 59.30  ? 272 SER A CB  1 
ATOM   1974  O  OG  . SER A 1 272 ? 159.180 134.525 197.956 1.00 59.30  ? 272 SER A OG  1 
ATOM   1975  N  N   . LEU A 1 273 ? 161.811 137.074 197.733 1.00 68.17  ? 273 LEU A N   1 
ATOM   1976  C  CA  . LEU A 1 273 ? 162.715 137.566 198.762 1.00 68.17  ? 273 LEU A CA  1 
ATOM   1977  C  C   . LEU A 1 273 ? 162.016 138.579 199.658 1.00 68.17  ? 273 LEU A C   1 
ATOM   1978  O  O   . LEU A 1 273 ? 161.908 139.758 199.309 1.00 68.17  ? 273 LEU A O   1 
ATOM   1979  C  CB  . LEU A 1 273 ? 163.952 138.202 198.134 1.00 68.17  ? 273 LEU A CB  1 
ATOM   1980  C  CG  . LEU A 1 273 ? 164.901 137.286 197.364 1.00 68.17  ? 273 LEU A CG  1 
ATOM   1981  C  CD1 . LEU A 1 273 ? 166.055 138.089 196.792 1.00 68.17  ? 273 LEU A CD1 1 
ATOM   1982  C  CD2 . LEU A 1 273 ? 165.407 136.183 198.260 1.00 68.17  ? 273 LEU A CD2 1 
ATOM   1983  N  N   . HIS A 1 274 ? 161.551 138.121 200.816 1.00 84.71  ? 274 HIS A N   1 
ATOM   1984  C  CA  . HIS A 1 274 ? 161.030 139.002 201.850 1.00 84.71  ? 274 HIS A CA  1 
ATOM   1985  C  C   . HIS A 1 274 ? 162.150 139.915 202.321 1.00 84.71  ? 274 HIS A C   1 
ATOM   1986  O  O   . HIS A 1 274 ? 163.232 139.442 202.690 1.00 84.71  ? 274 HIS A O   1 
ATOM   1987  C  CB  . HIS A 1 274 ? 160.460 138.207 203.025 1.00 84.71  ? 274 HIS A CB  1 
ATOM   1988  C  CG  . HIS A 1 274 ? 159.827 139.062 204.078 1.00 84.71  ? 274 HIS A CG  1 
ATOM   1989  N  ND1 . HIS A 1 274 ? 160.547 139.621 205.111 1.00 84.71  ? 274 HIS A ND1 1 
ATOM   1990  C  CD2 . HIS A 1 274 ? 158.544 139.457 204.255 1.00 84.71  ? 274 HIS A CD2 1 
ATOM   1991  C  CE1 . HIS A 1 274 ? 159.735 140.323 205.881 1.00 84.71  ? 274 HIS A CE1 1 
ATOM   1992  N  NE2 . HIS A 1 274 ? 158.514 140.239 205.384 1.00 84.71  ? 274 HIS A NE2 1 
ATOM   1993  N  N   . CYS A 1 275 ? 161.892 141.220 202.301 1.00 87.01  ? 275 CYS A N   1 
ATOM   1994  C  CA  . CYS A 1 275 ? 162.917 142.189 202.641 1.00 87.01  ? 275 CYS A CA  1 
ATOM   1995  C  C   . CYS A 1 275 ? 162.904 142.481 204.141 1.00 87.01  ? 275 CYS A C   1 
ATOM   1996  O  O   . CYS A 1 275 ? 161.854 142.630 204.771 1.00 87.01  ? 275 CYS A O   1 
ATOM   1997  C  CB  . CYS A 1 275 ? 162.716 143.478 201.846 1.00 87.01  ? 275 CYS A CB  1 
ATOM   1998  S  SG  . CYS A 1 275 ? 163.980 144.736 202.135 1.00 87.01  ? 275 CYS A SG  1 
ATOM   1999  N  N   . ALA A 1 276 ? 164.104 142.558 204.712 1.00 93.23  ? 276 ALA A N   1 
ATOM   2000  C  CA  . ALA A 1 276 ? 164.263 142.907 206.117 1.00 93.23  ? 276 ALA A CA  1 
ATOM   2001  C  C   . ALA A 1 276 ? 164.989 144.240 206.244 1.00 93.23  ? 276 ALA A C   1 
ATOM   2002  O  O   . ALA A 1 276 ? 165.948 144.503 205.511 1.00 93.23  ? 276 ALA A O   1 
ATOM   2003  C  CB  . ALA A 1 276 ? 165.016 141.808 206.867 1.00 93.23  ? 276 ALA A CB  1 
ATOM   2004  N  N   . GLU A 1 277 ? 164.542 145.084 207.172 1.00 92.85  ? 277 GLU A N   1 
ATOM   2005  C  CA  . GLU A 1 277 ? 165.120 146.411 207.351 1.00 92.85  ? 277 GLU A CA  1 
ATOM   2006  C  C   . GLU A 1 277 ? 166.394 146.360 208.188 1.00 92.85  ? 277 GLU A C   1 
ATOM   2007  O  O   . GLU A 1 277 ? 166.655 147.260 208.992 1.00 92.85  ? 277 GLU A O   1 
ATOM   2008  C  CB  . GLU A 1 277 ? 164.088 147.348 207.986 1.00 92.85  ? 277 GLU A CB  1 
ATOM   2009  C  CG  . GLU A 1 277 ? 163.606 146.916 209.365 1.00 92.85  ? 277 GLU A CG  1 
ATOM   2010  C  CD  . GLU A 1 277 ? 162.528 147.828 209.917 1.00 92.85  ? 277 GLU A CD  1 
ATOM   2011  O  OE1 . GLU A 1 277 ? 162.141 148.784 209.214 1.00 92.85  ? 277 GLU A OE1 1 
ATOM   2012  O  OE2 . GLU A 1 277 ? 162.065 147.587 211.051 1.00 92.85  ? 277 GLU A OE2 1 
ATOM   2013  N  N   . ASP A 1 278 ? 167.203 145.320 207.991 1.00 93.47  ? 278 ASP A N   1 
ATOM   2014  C  CA  . ASP A 1 278 ? 168.430 145.151 208.758 1.00 93.47  ? 278 ASP A CA  1 
ATOM   2015  C  C   . ASP A 1 278 ? 169.620 144.950 207.831 1.00 93.47  ? 278 ASP A C   1 
ATOM   2016  O  O   . ASP A 1 278 ? 170.553 144.212 208.166 1.00 93.47  ? 278 ASP A O   1 
ATOM   2017  C  CB  . ASP A 1 278 ? 168.298 143.964 209.714 1.00 93.47  ? 278 ASP A CB  1 
ATOM   2018  C  CG  . ASP A 1 278 ? 167.264 144.199 210.797 1.00 93.47  ? 278 ASP A CG  1 
ATOM   2019  O  OD1 . ASP A 1 278 ? 167.053 145.369 211.177 1.00 93.47  ? 278 ASP A OD1 1 
ATOM   2020  O  OD2 . ASP A 1 278 ? 166.661 143.211 211.266 1.00 93.47  ? 278 ASP A OD2 1 
ATOM   2021  N  N   . ASP A 1 279 ? 169.596 145.609 206.669 1.00 92.77  ? 279 ASP A N   1 
ATOM   2022  C  CA  . ASP A 1 279 ? 170.587 145.400 205.618 1.00 92.77  ? 279 ASP A CA  1 
ATOM   2023  C  C   . ASP A 1 279 ? 170.683 143.921 205.272 1.00 92.77  ? 279 ASP A C   1 
ATOM   2024  O  O   . ASP A 1 279 ? 171.775 143.403 205.014 1.00 92.77  ? 279 ASP A O   1 
ATOM   2025  C  CB  . ASP A 1 279 ? 171.957 145.944 206.036 1.00 92.77  ? 279 ASP A CB  1 
ATOM   2026  C  CG  . ASP A 1 279 ? 171.984 147.456 206.118 1.00 92.77  ? 279 ASP A CG  1 
ATOM   2027  O  OD1 . ASP A 1 279 ? 171.208 148.107 205.389 1.00 92.77  ? 279 ASP A OD1 1 
ATOM   2028  O  OD2 . ASP A 1 279 ? 172.787 147.994 206.908 1.00 92.77  ? 279 ASP A OD2 1 
ATOM   2029  N  N   . SER A 1 280 ? 169.544 143.233 205.271 1.00 93.69  ? 280 SER A N   1 
ATOM   2030  C  CA  . SER A 1 280 ? 169.513 141.800 205.035 1.00 93.69  ? 280 SER A CA  1 
ATOM   2031  C  C   . SER A 1 280 ? 168.282 141.457 204.213 1.00 93.69  ? 280 SER A C   1 
ATOM   2032  O  O   . SER A 1 280 ? 167.192 141.987 204.448 1.00 93.69  ? 280 SER A O   1 
ATOM   2033  C  CB  . SER A 1 280 ? 169.508 141.012 206.350 1.00 93.69  ? 280 SER A CB  1 
ATOM   2034  O  OG  . SER A 1 280 ? 170.699 141.236 207.084 1.00 93.69  ? 280 SER A OG  1 
ATOM   2035  N  N   . ILE A 1 281 ? 168.470 140.567 203.243 1.00 86.47  ? 281 ILE A N   1 
ATOM   2036  C  CA  . ILE A 1 281 ? 167.389 140.055 202.412 1.00 86.47  ? 281 ILE A CA  1 
ATOM   2037  C  C   . ILE A 1 281 ? 167.126 138.617 202.836 1.00 86.47  ? 281 ILE A C   1 
ATOM   2038  O  O   . ILE A 1 281 ? 168.046 137.919 203.278 1.00 86.47  ? 281 ILE A O   1 
ATOM   2039  C  CB  . ILE A 1 281 ? 167.733 140.152 200.912 1.00 86.47  ? 281 ILE A CB  1 
ATOM   2040  C  CG1 . ILE A 1 281 ? 166.481 139.951 200.058 1.00 86.47  ? 281 ILE A CG1 1 
ATOM   2041  C  CG2 . ILE A 1 281 ? 168.823 139.159 200.532 1.00 86.47  ? 281 ILE A CG2 1 
ATOM   2042  C  CD1 . ILE A 1 281 ? 165.462 141.053 200.212 1.00 86.47  ? 281 ILE A CD1 1 
ATOM   2043  N  N   . SER A 1 282 ? 165.872 138.185 202.733 1.00 81.76  ? 282 SER A N   1 
ATOM   2044  C  CA  . SER A 1 282 ? 165.480 136.863 203.193 1.00 81.76  ? 282 SER A CA  1 
ATOM   2045  C  C   . SER A 1 282 ? 164.703 136.139 202.103 1.00 81.76  ? 282 SER A C   1 
ATOM   2046  O  O   . SER A 1 282 ? 164.059 136.756 201.252 1.00 81.76  ? 282 SER A O   1 
ATOM   2047  C  CB  . SER A 1 282 ? 164.638 136.942 204.474 1.00 81.76  ? 282 SER A CB  1 
ATOM   2048  O  OG  . SER A 1 282 ? 163.398 137.581 204.231 1.00 81.76  ? 282 SER A OG  1 
ATOM   2049  N  N   . VAL A 1 283 ? 164.777 134.810 202.140 1.00 74.55  ? 283 VAL A N   1 
ATOM   2050  C  CA  . VAL A 1 283 ? 164.030 133.965 201.217 1.00 74.55  ? 283 VAL A CA  1 
ATOM   2051  C  C   . VAL A 1 283 ? 162.686 133.641 201.855 1.00 74.55  ? 283 VAL A C   1 
ATOM   2052  O  O   . VAL A 1 283 ? 162.564 133.606 203.084 1.00 74.55  ? 283 VAL A O   1 
ATOM   2053  C  CB  . VAL A 1 283 ? 164.817 132.687 200.867 1.00 74.55  ? 283 VAL A CB  1 
ATOM   2054  C  CG1 . VAL A 1 283 ? 164.965 131.794 202.089 1.00 74.55  ? 283 VAL A CG1 1 
ATOM   2055  C  CG2 . VAL A 1 283 ? 164.157 131.938 199.720 1.00 74.55  ? 283 VAL A CG2 1 
ATOM   2056  N  N   . SER A 1 284 ? 161.663 133.423 201.031 1.00 69.16  ? 284 SER A N   1 
ATOM   2057  C  CA  . SER A 1 284 ? 160.339 133.121 201.557 1.00 69.16  ? 284 SER A CA  1 
ATOM   2058  C  C   . SER A 1 284 ? 159.599 132.140 200.658 1.00 69.16  ? 284 SER A C   1 
ATOM   2059  O  O   . SER A 1 284 ? 158.609 132.502 200.015 1.00 69.16  ? 284 SER A O   1 
ATOM   2060  C  CB  . SER A 1 284 ? 159.527 134.407 201.728 1.00 69.16  ? 284 SER A CB  1 
ATOM   2061  O  OG  . SER A 1 284 ? 159.258 135.011 200.476 1.00 69.16  ? 284 SER A OG  1 
ATOM   2062  N  N   . GLY A 1 285 ? 160.071 130.897 200.608 1.00 67.09  ? 285 GLY A N   1 
ATOM   2063  C  CA  . GLY A 1 285 ? 159.405 129.864 199.841 1.00 67.09  ? 285 GLY A CA  1 
ATOM   2064  C  C   . GLY A 1 285 ? 159.658 129.953 198.351 1.00 67.09  ? 285 GLY A C   1 
ATOM   2065  O  O   . GLY A 1 285 ? 159.569 131.033 197.761 1.00 67.09  ? 285 GLY A O   1 
ATOM   2066  N  N   . GLN A 1 286 ? 159.971 128.819 197.730 1.00 69.73  ? 286 GLN A N   1 
ATOM   2067  C  CA  . GLN A 1 286 ? 160.227 128.754 196.300 1.00 69.73  ? 286 GLN A CA  1 
ATOM   2068  C  C   . GLN A 1 286 ? 158.926 128.496 195.559 1.00 69.73  ? 286 GLN A C   1 
ATOM   2069  O  O   . GLN A 1 286 ? 157.838 128.630 196.127 1.00 69.73  ? 286 GLN A O   1 
ATOM   2070  C  CB  . GLN A 1 286 ? 161.235 127.652 195.960 1.00 69.73  ? 286 GLN A CB  1 
ATOM   2071  C  CG  . GLN A 1 286 ? 162.633 127.890 196.495 1.00 69.73  ? 286 GLN A CG  1 
ATOM   2072  C  CD  . GLN A 1 286 ? 163.592 126.782 196.111 1.00 69.73  ? 286 GLN A CD  1 
ATOM   2073  O  OE1 . GLN A 1 286 ? 163.199 125.794 195.491 1.00 69.73  ? 286 GLN A OE1 1 
ATOM   2074  N  NE2 . GLN A 1 286 ? 164.859 126.942 196.472 1.00 69.73  ? 286 GLN A NE2 1 
ATOM   2075  N  N   . ASN A 1 287 ? 159.051 128.124 194.288 1.00 75.48  ? 287 ASN A N   1 
ATOM   2076  C  CA  . ASN A 1 287 ? 157.939 127.733 193.430 1.00 75.48  ? 287 ASN A CA  1 
ATOM   2077  C  C   . ASN A 1 287 ? 158.468 127.074 192.162 1.00 75.48  ? 287 ASN A C   1 
ATOM   2078  O  O   . ASN A 1 287 ? 158.352 127.615 191.060 1.00 75.48  ? 287 ASN A O   1 
ATOM   2079  C  CB  . ASN A 1 287 ? 157.053 128.931 193.095 1.00 75.48  ? 287 ASN A CB  1 
ATOM   2080  C  CG  . ASN A 1 287 ? 155.744 128.528 192.442 1.00 75.48  ? 287 ASN A CG  1 
ATOM   2081  O  OD1 . ASN A 1 287 ? 155.489 127.347 192.210 1.00 75.48  ? 287 ASN A OD1 1 
ATOM   2082  N  ND2 . ASN A 1 287 ? 154.903 129.513 192.146 1.00 75.48  ? 287 ASN A ND2 1 
ATOM   2083  N  N   . SER A 1 288 ? 159.057 125.888 192.312 1.00 82.29  ? 288 SER A N   1 
ATOM   2084  C  CA  . SER A 1 288 ? 159.766 125.217 191.228 1.00 82.29  ? 288 SER A CA  1 
ATOM   2085  C  C   . SER A 1 288 ? 158.848 124.834 190.075 1.00 82.29  ? 288 SER A C   1 
ATOM   2086  O  O   . SER A 1 288 ? 159.323 124.518 188.980 1.00 82.29  ? 288 SER A O   1 
ATOM   2087  C  CB  . SER A 1 288 ? 160.478 123.971 191.760 1.00 82.29  ? 288 SER A CB  1 
ATOM   2088  O  OG  . SER A 1 288 ? 159.545 123.007 192.216 1.00 82.29  ? 288 SER A OG  1 
ATOM   2089  N  N   . LEU A 1 289 ? 157.537 124.847 190.312 1.00 85.46  ? 289 LEU A N   1 
ATOM   2090  C  CA  . LEU A 1 289 ? 156.576 124.490 189.275 1.00 85.46  ? 289 LEU A CA  1 
ATOM   2091  C  C   . LEU A 1 289 ? 156.684 125.443 188.091 1.00 85.46  ? 289 LEU A C   1 
ATOM   2092  O  O   . LEU A 1 289 ? 156.033 126.491 188.069 1.00 85.46  ? 289 LEU A O   1 
ATOM   2093  C  CB  . LEU A 1 289 ? 155.153 124.495 189.838 1.00 85.46  ? 289 LEU A CB  1 
ATOM   2094  C  CG  . LEU A 1 289 ? 154.836 123.430 190.889 1.00 85.46  ? 289 LEU A CG  1 
ATOM   2095  C  CD1 . LEU A 1 289 ? 153.437 123.631 191.450 1.00 85.46  ? 289 LEU A CD1 1 
ATOM   2096  C  CD2 . LEU A 1 289 ? 154.987 122.036 190.300 1.00 85.46  ? 289 LEU A CD2 1 
ATOM   2097  N  N   . CYS A 1 290 ? 157.506 125.088 187.106 1.00 93.95  ? 290 CYS A N   1 
ATOM   2098  C  CA  . CYS A 1 290 ? 157.746 125.903 185.931 1.00 93.95  ? 290 CYS A CA  1 
ATOM   2099  C  C   . CYS A 1 290 ? 157.785 125.009 184.688 1.00 93.95  ? 290 CYS A C   1 
ATOM   2100  O  O   . CYS A 1 290 ? 157.896 123.776 184.812 1.00 93.95  ? 290 CYS A O   1 
ATOM   2101  C  CB  . CYS A 1 290 ? 159.023 126.712 186.144 1.00 93.95  ? 290 CYS A CB  1 
ATOM   2102  S  SG  . CYS A 1 290 ? 158.915 127.950 187.450 1.00 93.95  ? 290 CYS A SG  1 
ATOM   2103  N  N   . HIS A 1 291 ? 157.687 125.617 183.508 1.00 99.91  ? 291 HIS A N   1 
ATOM   2104  C  CA  . HIS A 1 291 ? 157.823 124.905 182.244 1.00 99.91  ? 291 HIS A CA  1 
ATOM   2105  C  C   . HIS A 1 291 ? 158.976 125.505 181.451 1.00 99.91  ? 291 HIS A C   1 
ATOM   2106  O  O   . HIS A 1 291 ? 160.104 125.005 181.502 1.00 99.91  ? 291 HIS A O   1 
ATOM   2107  C  CB  . HIS A 1 291 ? 156.519 124.972 181.446 1.00 99.91  ? 291 HIS A CB  1 
ATOM   2108  C  CG  . HIS A 1 291 ? 156.537 124.165 180.185 1.00 99.91  ? 291 HIS A CG  1 
ATOM   2109  N  ND1 . HIS A 1 291 ? 157.003 124.665 178.988 1.00 99.91  ? 291 HIS A ND1 1 
ATOM   2110  C  CD2 . HIS A 1 291 ? 156.139 122.895 179.933 1.00 99.91  ? 291 HIS A CD2 1 
ATOM   2111  C  CE1 . HIS A 1 291 ? 156.894 123.737 178.054 1.00 99.91  ? 291 HIS A CE1 1 
ATOM   2112  N  NE2 . HIS A 1 291 ? 156.373 122.654 178.601 1.00 99.91  ? 291 HIS A NE2 1 
ATOM   2113  N  N   . GLN A 1 292 ? 158.698 126.584 180.721 1.00 91.60  ? 292 GLN A N   1 
ATOM   2114  C  CA  . GLN A 1 292 ? 159.733 127.339 180.028 1.00 91.60  ? 292 GLN A CA  1 
ATOM   2115  C  C   . GLN A 1 292 ? 159.303 128.795 179.915 1.00 91.60  ? 292 GLN A C   1 
ATOM   2116  O  O   . GLN A 1 292 ? 158.165 129.081 179.530 1.00 91.60  ? 292 GLN A O   1 
ATOM   2117  C  CB  . GLN A 1 292 ? 160.012 126.743 178.648 1.00 91.60  ? 292 GLN A CB  1 
ATOM   2118  C  CG  . GLN A 1 292 ? 161.168 127.403 177.919 1.00 91.60  ? 292 GLN A CG  1 
ATOM   2119  C  CD  . GLN A 1 292 ? 162.478 127.263 178.669 1.00 91.60  ? 292 GLN A CD  1 
ATOM   2120  O  OE1 . GLN A 1 292 ? 162.968 128.219 179.271 1.00 91.60  ? 292 GLN A OE1 1 
ATOM   2121  N  NE2 . GLN A 1 292 ? 163.049 126.065 178.643 1.00 91.60  ? 292 GLN A NE2 1 
ATOM   2122  N  N   . ILE A 1 293 ? 160.197 129.718 180.248 1.00 80.06  ? 293 ILE A N   1 
ATOM   2123  C  CA  . ILE A 1 293 ? 159.852 131.120 180.365 1.00 80.06  ? 293 ILE A CA  1 
ATOM   2124  C  C   . ILE A 1 293 ? 160.553 131.911 179.267 1.00 80.06  ? 293 ILE A C   1 
ATOM   2125  O  O   . ILE A 1 293 ? 161.729 131.709 178.975 1.00 80.06  ? 293 ILE A O   1 
ATOM   2126  C  CB  . ILE A 1 293 ? 160.202 131.680 181.767 1.00 80.06  ? 293 ILE A CB  1 
ATOM   2127  C  CG1 . ILE A 1 293 ? 159.407 130.957 182.857 1.00 80.06  ? 293 ILE A CG1 1 
ATOM   2128  C  CG2 . ILE A 1 293 ? 159.937 133.173 181.832 1.00 80.06  ? 293 ILE A CG2 1 
ATOM   2129  C  CD1 . ILE A 1 293 ? 160.114 129.760 183.451 1.00 80.06  ? 293 ILE A CD1 1 
ATOM   2130  N  N   . THR A 1 294 ? 159.814 132.828 178.641 1.00 73.74  ? 294 THR A N   1 
ATOM   2131  C  CA  . THR A 1 294 ? 160.388 133.749 177.669 1.00 73.74  ? 294 THR A CA  1 
ATOM   2132  C  C   . THR A 1 294 ? 160.470 135.146 178.269 1.00 73.74  ? 294 THR A C   1 
ATOM   2133  O  O   . THR A 1 294 ? 161.444 135.873 178.046 1.00 73.74  ? 294 THR A O   1 
ATOM   2134  C  CB  . THR A 1 294 ? 159.559 133.768 176.382 1.00 73.74  ? 294 THR A CB  1 
ATOM   2135  O  OG1 . THR A 1 294 ? 159.524 132.452 175.817 1.00 73.74  ? 294 THR A OG1 1 
ATOM   2136  C  CG2 . THR A 1 294 ? 160.159 134.735 175.369 1.00 73.74  ? 294 THR A CG2 1 
ATOM   2137  N  N   . ALA A 1 295 ? 159.451 135.527 179.036 1.00 59.05  ? 295 ALA A N   1 
ATOM   2138  C  CA  . ALA A 1 295 ? 159.442 136.811 179.719 1.00 59.05  ? 295 ALA A CA  1 
ATOM   2139  C  C   . ALA A 1 295 ? 158.532 136.708 180.932 1.00 59.05  ? 295 ALA A C   1 
ATOM   2140  O  O   . ALA A 1 295 ? 157.775 135.746 181.072 1.00 59.05  ? 295 ALA A O   1 
ATOM   2141  C  CB  . ALA A 1 295 ? 158.977 137.943 178.797 1.00 59.05  ? 295 ALA A CB  1 
ATOM   2142  N  N   . ALA A 1 296 ? 158.619 137.703 181.810 1.00 49.30  ? 296 ALA A N   1 
ATOM   2143  C  CA  . ALA A 1 296 ? 157.770 137.750 182.991 1.00 49.30  ? 296 ALA A CA  1 
ATOM   2144  C  C   . ALA A 1 296 ? 157.874 139.133 183.610 1.00 49.30  ? 296 ALA A C   1 
ATOM   2145  O  O   . ALA A 1 296 ? 158.822 139.878 183.353 1.00 49.30  ? 296 ALA A O   1 
ATOM   2146  C  CB  . ALA A 1 296 ? 158.150 136.675 184.013 1.00 49.30  ? 296 ALA A CB  1 
ATOM   2147  N  N   . CYS A 1 297 ? 156.880 139.465 184.430 1.00 48.91  ? 297 CYS A N   1 
ATOM   2148  C  CA  . CYS A 1 297 ? 156.864 140.749 185.111 1.00 48.91  ? 297 CYS A CA  1 
ATOM   2149  C  C   . CYS A 1 297 ? 156.057 140.625 186.393 1.00 48.91  ? 297 CYS A C   1 
ATOM   2150  O  O   . CYS A 1 297 ? 155.237 139.717 186.552 1.00 48.91  ? 297 CYS A O   1 
ATOM   2151  C  CB  . CYS A 1 297 ? 156.287 141.856 184.221 1.00 48.91  ? 297 CYS A CB  1 
ATOM   2152  S  SG  . CYS A 1 297 ? 154.546 141.649 183.812 1.00 48.91  ? 297 CYS A SG  1 
ATOM   2153  N  N   . LYS A 1 298 ? 156.304 141.556 187.305 1.00 48.10  ? 298 LYS A N   1 
ATOM   2154  C  CA  . LYS A 1 298 ? 155.638 141.595 188.595 1.00 48.10  ? 298 LYS A CA  1 
ATOM   2155  C  C   . LYS A 1 298 ? 154.619 142.728 188.635 1.00 48.10  ? 298 LYS A C   1 
ATOM   2156  O  O   . LYS A 1 298 ? 154.947 143.898 188.424 1.00 48.10  ? 298 LYS A O   1 
ATOM   2157  C  CB  . LYS A 1 298 ? 156.661 141.772 189.715 1.00 48.10  ? 298 LYS A CB  1 
ATOM   2158  C  CG  . LYS A 1 298 ? 156.069 141.785 191.107 1.00 48.10  ? 298 LYS A CG  1 
ATOM   2159  C  CD  . LYS A 1 298 ? 157.156 141.911 192.157 1.00 48.10  ? 298 LYS A CD  1 
ATOM   2160  C  CE  . LYS A 1 298 ? 156.581 141.849 193.559 1.00 48.10  ? 298 LYS A CE  1 
ATOM   2161  N  NZ  . LYS A 1 298 ? 155.749 143.042 193.867 1.00 48.10  ? 298 LYS A NZ  1 
ATOM   2162  N  N   . HIS A 1 299 ? 153.367 142.366 188.909 1.00 56.14  ? 299 HIS A N   1 
ATOM   2163  C  CA  . HIS A 1 299 ? 152.297 143.360 188.953 1.00 56.14  ? 299 HIS A CA  1 
ATOM   2164  C  C   . HIS A 1 299 ? 151.819 143.482 190.393 1.00 56.14  ? 299 HIS A C   1 
ATOM   2165  O  O   . HIS A 1 299 ? 151.429 142.481 191.001 1.00 56.14  ? 299 HIS A O   1 
ATOM   2166  C  CB  . HIS A 1 299 ? 151.154 142.974 188.026 1.00 56.14  ? 299 HIS A CB  1 
ATOM   2167  C  CG  . HIS A 1 299 ? 150.106 144.034 187.891 1.00 56.14  ? 299 HIS A CG  1 
ATOM   2168  N  ND1 . HIS A 1 299 ? 148.874 143.795 187.322 1.00 56.14  ? 299 HIS A ND1 1 
ATOM   2169  C  CD2 . HIS A 1 299 ? 150.108 145.339 188.249 1.00 56.14  ? 299 HIS A CD2 1 
ATOM   2170  C  CE1 . HIS A 1 299 ? 148.161 144.907 187.337 1.00 56.14  ? 299 HIS A CE1 1 
ATOM   2171  N  NE2 . HIS A 1 299 ? 148.887 145.859 187.894 1.00 56.14  ? 299 HIS A NE2 1 
ATOM   2172  N  N   . GLY A 1 300 ? 151.857 144.699 190.931 1.00 59.24  ? 300 GLY A N   1 
ATOM   2173  C  CA  . GLY A 1 300 ? 151.385 144.955 192.277 1.00 59.24  ? 300 GLY A CA  1 
ATOM   2174  C  C   . GLY A 1 300 ? 152.053 144.098 193.332 1.00 59.24  ? 300 GLY A C   1 
ATOM   2175  O  O   . GLY A 1 300 ? 152.906 144.577 194.084 1.00 59.24  ? 300 GLY A O   1 
ATOM   2176  N  N   . GLY A 1 301 ? 151.670 142.826 193.395 1.00 58.45  ? 301 GLY A N   1 
ATOM   2177  C  CA  . GLY A 1 301 ? 152.235 141.921 194.374 1.00 58.45  ? 301 GLY A CA  1 
ATOM   2178  C  C   . GLY A 1 301 ? 152.171 140.462 193.975 1.00 58.45  ? 301 GLY A C   1 
ATOM   2179  O  O   . GLY A 1 301 ? 152.226 139.580 194.837 1.00 58.45  ? 301 GLY A O   1 
ATOM   2180  N  N   . ASP A 1 302 ? 152.052 140.187 192.678 1.00 58.71  ? 302 ASP A N   1 
ATOM   2181  C  CA  . ASP A 1 302 ? 152.057 138.821 192.179 1.00 58.71  ? 302 ASP A CA  1 
ATOM   2182  C  C   . ASP A 1 302 ? 152.821 138.750 190.864 1.00 58.71  ? 302 ASP A C   1 
ATOM   2183  O  O   . ASP A 1 302 ? 153.051 139.767 190.203 1.00 58.71  ? 302 ASP A O   1 
ATOM   2184  C  CB  . ASP A 1 302 ? 150.627 138.273 192.010 1.00 58.71  ? 302 ASP A CB  1 
ATOM   2185  C  CG  . ASP A 1 302 ? 149.786 139.086 191.040 1.00 58.71  ? 302 ASP A CG  1 
ATOM   2186  O  OD1 . ASP A 1 302 ? 150.273 140.105 190.512 1.00 58.71  ? 302 ASP A OD1 1 
ATOM   2187  O  OD2 . ASP A 1 302 ? 148.619 138.704 190.812 1.00 58.71  ? 302 ASP A OD2 1 
ATOM   2188  N  N   . LEU A 1 303 ? 153.214 137.533 190.498 1.00 55.77  ? 303 LEU A N   1 
ATOM   2189  C  CA  . LEU A 1 303 ? 154.052 137.301 189.331 1.00 55.77  ? 303 LEU A CA  1 
ATOM   2190  C  C   . LEU A 1 303 ? 153.208 136.842 188.151 1.00 55.77  ? 303 LEU A C   1 
ATOM   2191  O  O   . LEU A 1 303 ? 152.421 135.897 188.265 1.00 55.77  ? 303 LEU A O   1 
ATOM   2192  C  CB  . LEU A 1 303 ? 155.123 136.253 189.649 1.00 55.77  ? 303 LEU A CB  1 
ATOM   2193  C  CG  . LEU A 1 303 ? 156.251 135.966 188.656 1.00 55.77  ? 303 LEU A CG  1 
ATOM   2194  C  CD1 . LEU A 1 303 ? 157.476 135.472 189.399 1.00 55.77  ? 303 LEU A CD1 1 
ATOM   2195  C  CD2 . LEU A 1 303 ? 155.835 134.939 187.619 1.00 55.77  ? 303 LEU A CD2 1 
ATOM   2196  N  N   . TYR A 1 304 ? 153.382 137.512 187.015 1.00 56.38  ? 304 TYR A N   1 
ATOM   2197  C  CA  . TYR A 1 304 ? 152.752 137.119 185.762 1.00 56.38  ? 304 TYR A CA  1 
ATOM   2198  C  C   . TYR A 1 304 ? 153.841 136.686 184.794 1.00 56.38  ? 304 TYR A C   1 
ATOM   2199  O  O   . TYR A 1 304 ? 154.768 137.454 184.514 1.00 56.38  ? 304 TYR A O   1 
ATOM   2200  C  CB  . TYR A 1 304 ? 151.928 138.263 185.164 1.00 56.38  ? 304 TYR A CB  1 
ATOM   2201  C  CG  . TYR A 1 304 ? 150.700 138.640 185.967 1.00 56.38  ? 304 TYR A CG  1 
ATOM   2202  C  CD1 . TYR A 1 304 ? 150.224 137.823 186.977 1.00 56.38  ? 304 TYR A CD1 1 
ATOM   2203  C  CD2 . TYR A 1 304 ? 150.011 139.812 185.704 1.00 56.38  ? 304 TYR A CD2 1 
ATOM   2204  C  CE1 . TYR A 1 304 ? 149.105 138.173 187.706 1.00 56.38  ? 304 TYR A CE1 1 
ATOM   2205  C  CE2 . TYR A 1 304 ? 148.892 140.166 186.425 1.00 56.38  ? 304 TYR A CE2 1 
ATOM   2206  C  CZ  . TYR A 1 304 ? 148.443 139.341 187.426 1.00 56.38  ? 304 TYR A CZ  1 
ATOM   2207  O  OH  . TYR A 1 304 ? 147.327 139.683 188.154 1.00 56.38  ? 304 TYR A OH  1 
ATOM   2208  N  N   . VAL A 1 305 ? 153.732 135.459 184.288 1.00 65.97  ? 305 VAL A N   1 
ATOM   2209  C  CA  . VAL A 1 305 ? 154.789 134.855 183.488 1.00 65.97  ? 305 VAL A CA  1 
ATOM   2210  C  C   . VAL A 1 305 ? 154.252 134.497 182.108 1.00 65.97  ? 305 VAL A C   1 
ATOM   2211  O  O   . VAL A 1 305 ? 153.092 134.102 181.949 1.00 65.97  ? 305 VAL A O   1 
ATOM   2212  C  CB  . VAL A 1 305 ? 155.390 133.615 184.192 1.00 65.97  ? 305 VAL A CB  1 
ATOM   2213  C  CG1 . VAL A 1 305 ? 154.363 132.505 184.306 1.00 65.97  ? 305 VAL A CG1 1 
ATOM   2214  C  CG2 . VAL A 1 305 ? 156.630 133.134 183.468 1.00 65.97  ? 305 VAL A CG2 1 
ATOM   2215  N  N   . VAL A 1 306 ? 155.112 134.654 181.103 1.00 71.95  ? 306 VAL A N   1 
ATOM   2216  C  CA  . VAL A 1 306 ? 154.802 134.348 179.711 1.00 71.95  ? 306 VAL A CA  1 
ATOM   2217  C  C   . VAL A 1 306 ? 155.902 133.453 179.159 1.00 71.95  ? 306 VAL A C   1 
ATOM   2218  O  O   . VAL A 1 306 ? 157.084 133.813 179.206 1.00 71.95  ? 306 VAL A O   1 
ATOM   2219  C  CB  . VAL A 1 306 ? 154.676 135.623 178.857 1.00 71.95  ? 306 VAL A CB  1 
ATOM   2220  C  CG1 . VAL A 1 306 ? 154.531 135.265 177.389 1.00 71.95  ? 306 VAL A CG1 1 
ATOM   2221  C  CG2 . VAL A 1 306 ? 153.500 136.452 179.319 1.00 71.95  ? 306 VAL A CG2 1 
ATOM   2222  N  N   . GLY A 1 307 ? 155.513 132.297 178.633 1.00 80.57  ? 307 GLY A N   1 
ATOM   2223  C  CA  . GLY A 1 307 ? 156.467 131.371 178.053 1.00 80.57  ? 307 GLY A CA  1 
ATOM   2224  C  C   . GLY A 1 307 ? 155.845 130.071 177.584 1.00 80.57  ? 307 GLY A C   1 
ATOM   2225  O  O   . GLY A 1 307 ? 154.714 129.747 177.943 1.00 80.57  ? 307 GLY A O   1 
ATOM   2226  N  N   . TYR A 1 312 ? 152.960 127.821 174.497 1.00 96.69  ? 312 TYR A N   1 
ATOM   2227  C  CA  . TYR A 1 312 ? 154.374 127.496 174.361 1.00 96.69  ? 312 TYR A CA  1 
ATOM   2228  C  C   . TYR A 1 312 ? 155.211 128.766 174.247 1.00 96.69  ? 312 TYR A C   1 
ATOM   2229  O  O   . TYR A 1 312 ? 156.329 128.831 174.759 1.00 96.69  ? 312 TYR A O   1 
ATOM   2230  C  CB  . TYR A 1 312 ? 154.599 126.585 173.149 1.00 96.69  ? 312 TYR A CB  1 
ATOM   2231  C  CG  . TYR A 1 312 ? 154.230 127.212 171.823 1.00 96.69  ? 312 TYR A CG  1 
ATOM   2232  C  CD1 . TYR A 1 312 ? 152.931 127.144 171.338 1.00 96.69  ? 312 TYR A CD1 1 
ATOM   2233  C  CD2 . TYR A 1 312 ? 155.186 127.852 171.045 1.00 96.69  ? 312 TYR A CD2 1 
ATOM   2234  C  CE1 . TYR A 1 312 ? 152.589 127.714 170.125 1.00 96.69  ? 312 TYR A CE1 1 
ATOM   2235  C  CE2 . TYR A 1 312 ? 154.854 128.425 169.833 1.00 96.69  ? 312 TYR A CE2 1 
ATOM   2236  C  CZ  . TYR A 1 312 ? 153.555 128.351 169.376 1.00 96.69  ? 312 TYR A CZ  1 
ATOM   2237  O  OH  . TYR A 1 312 ? 153.223 128.918 168.167 1.00 96.69  ? 312 TYR A OH  1 
ATOM   2238  N  N   . MET A 1 313 ? 154.660 129.778 173.578 1.00 93.77  ? 313 MET A N   1 
ATOM   2239  C  CA  . MET A 1 313 ? 155.316 131.068 173.406 1.00 93.77  ? 313 MET A CA  1 
ATOM   2240  C  C   . MET A 1 313 ? 154.337 132.235 173.432 1.00 93.77  ? 313 MET A C   1 
ATOM   2241  O  O   . MET A 1 313 ? 154.717 133.357 173.081 1.00 93.77  ? 313 MET A O   1 
ATOM   2242  C  CB  . MET A 1 313 ? 156.115 131.093 172.100 1.00 93.77  ? 313 MET A CB  1 
ATOM   2243  C  CG  . MET A 1 313 ? 157.389 130.271 172.122 1.00 93.77  ? 313 MET A CG  1 
ATOM   2244  S  SD  . MET A 1 313 ? 158.534 130.903 173.356 1.00 93.77  ? 313 MET A SD  1 
ATOM   2245  C  CE  . MET A 1 313 ? 158.931 132.484 172.620 1.00 93.77  ? 313 MET A CE  1 
ATOM   2246  N  N   . LEU A 1 314 ? 153.085 132.002 173.842 1.00 87.77  ? 314 LEU A N   1 
ATOM   2247  C  CA  . LEU A 1 314 ? 152.093 133.072 173.857 1.00 87.77  ? 314 LEU A CA  1 
ATOM   2248  C  C   . LEU A 1 314 ? 151.086 132.903 174.990 1.00 87.77  ? 314 LEU A C   1 
ATOM   2249  O  O   . LEU A 1 314 ? 149.984 133.458 174.925 1.00 87.77  ? 314 LEU A O   1 
ATOM   2250  C  CB  . LEU A 1 314 ? 151.383 133.161 172.494 1.00 87.77  ? 314 LEU A CB  1 
ATOM   2251  C  CG  . LEU A 1 314 ? 150.674 131.929 171.913 1.00 87.77  ? 314 LEU A CG  1 
ATOM   2252  C  CD1 . LEU A 1 314 ? 149.226 131.809 172.372 1.00 87.77  ? 314 LEU A CD1 1 
ATOM   2253  C  CD2 . LEU A 1 314 ? 150.756 131.935 170.392 1.00 87.77  ? 314 LEU A CD2 1 
ATOM   2254  N  N   . ARG A 1 315 ? 151.450 132.169 176.038 1.00 88.04  ? 315 ARG A N   1 
ATOM   2255  C  CA  . ARG A 1 315 ? 150.566 131.906 177.168 1.00 88.04  ? 315 ARG A CA  1 
ATOM   2256  C  C   . ARG A 1 315 ? 150.972 132.792 178.336 1.00 88.04  ? 315 ARG A C   1 
ATOM   2257  O  O   . ARG A 1 315 ? 151.892 133.607 178.210 1.00 88.04  ? 315 ARG A O   1 
ATOM   2258  C  CB  . ARG A 1 315 ? 150.616 130.432 177.574 1.00 88.04  ? 315 ARG A CB  1 
ATOM   2259  C  CG  . ARG A 1 315 ? 149.686 129.525 176.786 1.00 88.04  ? 315 ARG A CG  1 
ATOM   2260  C  CD  . ARG A 1 315 ? 150.162 129.317 175.360 1.00 88.04  ? 315 ARG A CD  1 
ATOM   2261  N  NE  . ARG A 1 315 ? 149.376 128.300 174.670 1.00 88.04  ? 315 ARG A NE  1 
ATOM   2262  C  CZ  . ARG A 1 315 ? 149.518 127.990 173.385 1.00 88.04  ? 315 ARG A CZ  1 
ATOM   2263  N  NH1 . ARG A 1 315 ? 150.418 128.620 172.645 1.00 88.04  ? 315 ARG A NH1 1 
ATOM   2264  N  NH2 . ARG A 1 315 ? 148.760 127.049 172.840 1.00 88.04  ? 315 ARG A NH2 1 
ATOM   2265  N  N   . MET A 1 316 ? 150.288 132.631 179.468 1.00 77.59  ? 316 MET A N   1 
ATOM   2266  C  CA  . MET A 1 316 ? 150.587 133.382 180.683 1.00 77.59  ? 316 MET A CA  1 
ATOM   2267  C  C   . MET A 1 316 ? 150.052 132.622 181.891 1.00 77.59  ? 316 MET A C   1 
ATOM   2268  O  O   . MET A 1 316 ? 148.883 132.226 181.917 1.00 77.59  ? 316 MET A O   1 
ATOM   2269  C  CB  . MET A 1 316 ? 149.987 134.785 180.621 1.00 77.59  ? 316 MET A CB  1 
ATOM   2270  C  CG  . MET A 1 316 ? 150.241 135.603 181.881 1.00 77.59  ? 316 MET A CG  1 
ATOM   2271  S  SD  . MET A 1 316 ? 149.545 137.265 181.859 1.00 77.59  ? 316 MET A SD  1 
ATOM   2272  C  CE  . MET A 1 316 ? 150.713 138.110 180.806 1.00 77.59  ? 316 MET A CE  1 
ATOM   2273  N  N   . TRP A 1 317 ? 150.905 132.423 182.892 1.00 76.51  ? 317 TRP A N   1 
ATOM   2274  C  CA  . TRP A 1 317 ? 150.497 131.860 184.171 1.00 76.51  ? 317 TRP A CA  1 
ATOM   2275  C  C   . TRP A 1 317 ? 150.677 132.903 185.265 1.00 76.51  ? 317 TRP A C   1 
ATOM   2276  O  O   . TRP A 1 317 ? 151.425 133.870 185.098 1.00 76.51  ? 317 TRP A O   1 
ATOM   2277  C  CB  . TRP A 1 317 ? 151.306 130.609 184.522 1.00 76.51  ? 317 TRP A CB  1 
ATOM   2278  C  CG  . TRP A 1 317 ? 151.034 129.425 183.648 1.00 76.51  ? 317 TRP A CG  1 
ATOM   2279  C  CD1 . TRP A 1 317 ? 150.043 128.503 183.806 1.00 76.51  ? 317 TRP A CD1 1 
ATOM   2280  C  CD2 . TRP A 1 317 ? 151.786 129.014 182.500 1.00 76.51  ? 317 TRP A CD2 1 
ATOM   2281  N  NE1 . TRP A 1 317 ? 150.117 127.553 182.817 1.00 76.51  ? 317 TRP A NE1 1 
ATOM   2282  C  CE2 . TRP A 1 317 ? 151.180 127.843 182.003 1.00 76.51  ? 317 TRP A CE2 1 
ATOM   2283  C  CE3 . TRP A 1 317 ? 152.906 129.526 181.840 1.00 76.51  ? 317 TRP A CE3 1 
ATOM   2284  C  CZ2 . TRP A 1 317 ? 151.657 127.177 180.877 1.00 76.51  ? 317 TRP A CZ2 1 
ATOM   2285  C  CZ3 . TRP A 1 317 ? 153.378 128.863 180.723 1.00 76.51  ? 317 TRP A CZ3 1 
ATOM   2286  C  CH2 . TRP A 1 317 ? 152.755 127.701 180.252 1.00 76.51  ? 317 TRP A CH2 1 
ATOM   2287  N  N   . LYS A 1 318 ? 149.990 132.701 186.385 1.00 72.19  ? 318 LYS A N   1 
ATOM   2288  C  CA  . LYS A 1 318 ? 150.136 133.566 187.547 1.00 72.19  ? 318 LYS A CA  1 
ATOM   2289  C  C   . LYS A 1 318 ? 150.718 132.765 188.702 1.00 72.19  ? 318 LYS A C   1 
ATOM   2290  O  O   . LYS A 1 318 ? 150.429 131.575 188.853 1.00 72.19  ? 318 LYS A O   1 
ATOM   2291  C  CB  . LYS A 1 318 ? 148.792 134.180 187.952 1.00 72.19  ? 318 LYS A CB  1 
ATOM   2292  C  CG  . LYS A 1 318 ? 148.890 135.192 189.086 1.00 72.19  ? 318 LYS A CG  1 
ATOM   2293  C  CD  . LYS A 1 318 ? 148.554 134.616 190.450 1.00 72.19  ? 318 LYS A CD  1 
ATOM   2294  C  CE  . LYS A 1 318 ? 147.059 134.421 190.603 1.00 72.19  ? 318 LYS A CE  1 
ATOM   2295  N  NZ  . LYS A 1 318 ? 146.705 133.887 191.946 1.00 72.19  ? 318 LYS A NZ  1 
ATOM   2296  N  N   . CYS A 1 319 ? 151.544 133.416 189.514 1.00 72.63  ? 319 CYS A N   1 
ATOM   2297  C  CA  . CYS A 1 319 ? 152.171 132.771 190.660 1.00 72.63  ? 319 CYS A CA  1 
ATOM   2298  C  C   . CYS A 1 319 ? 151.279 132.941 191.884 1.00 72.63  ? 319 CYS A C   1 
ATOM   2299  O  O   . CYS A 1 319 ? 151.349 133.966 192.570 1.00 72.63  ? 319 CYS A O   1 
ATOM   2300  C  CB  . CYS A 1 319 ? 153.560 133.346 190.926 1.00 72.63  ? 319 CYS A CB  1 
ATOM   2301  S  SG  . CYS A 1 319 ? 154.447 132.543 192.280 1.00 72.63  ? 319 CYS A SG  1 
ATOM   2302  N  N   . ASN A 1 320 ? 150.444 131.940 192.150 1.00 82.28  ? 320 ASN A N   1 
ATOM   2303  C  CA  . ASN A 1 320 ? 149.617 131.892 193.352 1.00 82.28  ? 320 ASN A CA  1 
ATOM   2304  C  C   . ASN A 1 320 ? 150.477 131.273 194.449 1.00 82.28  ? 320 ASN A C   1 
ATOM   2305  O  O   . ASN A 1 320 ? 150.424 130.061 194.688 1.00 82.28  ? 320 ASN A O   1 
ATOM   2306  C  CB  . ASN A 1 320 ? 148.335 131.101 193.109 1.00 82.28  ? 320 ASN A CB  1 
ATOM   2307  C  CG  . ASN A 1 320 ? 147.326 131.271 194.225 1.00 82.28  ? 320 ASN A CG  1 
ATOM   2308  O  OD1 . ASN A 1 320 ? 147.581 131.962 195.210 1.00 82.28  ? 320 ASN A OD1 1 
ATOM   2309  N  ND2 . ASN A 1 320 ? 146.167 130.641 194.073 1.00 82.28  ? 320 ASN A ND2 1 
ATOM   2310  N  N   . ASN A 1 321 ? 151.279 132.117 195.105 1.00 84.88  ? 321 ASN A N   1 
ATOM   2311  C  CA  . ASN A 1 321 ? 152.238 131.634 196.093 1.00 84.88  ? 321 ASN A CA  1 
ATOM   2312  C  C   . ASN A 1 321 ? 151.584 131.352 197.439 1.00 84.88  ? 321 ASN A C   1 
ATOM   2313  O  O   . ASN A 1 321 ? 152.079 130.510 198.199 1.00 84.88  ? 321 ASN A O   1 
ATOM   2314  C  CB  . ASN A 1 321 ? 153.375 132.646 196.248 1.00 84.88  ? 321 ASN A CB  1 
ATOM   2315  C  CG  . ASN A 1 321 ? 152.886 134.022 196.673 1.00 84.88  ? 321 ASN A CG  1 
ATOM   2316  O  OD1 . ASN A 1 321 ? 151.703 134.221 196.952 1.00 84.88  ? 321 ASN A OD1 1 
ATOM   2317  N  ND2 . ASN A 1 321 ? 153.801 134.982 196.721 1.00 84.88  ? 321 ASN A ND2 1 
ATOM   2318  N  N   . ALA A 1 322 ? 150.491 132.049 197.760 1.00 83.34  ? 322 ALA A N   1 
ATOM   2319  C  CA  . ALA A 1 322 ? 149.775 131.773 199.002 1.00 83.34  ? 322 ALA A CA  1 
ATOM   2320  C  C   . ALA A 1 322 ? 149.289 130.331 199.037 1.00 83.34  ? 322 ALA A C   1 
ATOM   2321  O  O   . ALA A 1 322 ? 149.355 129.666 200.078 1.00 83.34  ? 322 ALA A O   1 
ATOM   2322  C  CB  . ALA A 1 322 ? 148.606 132.744 199.163 1.00 83.34  ? 322 ALA A CB  1 
ATOM   2323  N  N   . THR A 1 323 ? 148.800 129.830 197.906 1.00 84.05  ? 323 THR A N   1 
ATOM   2324  C  CA  . THR A 1 323 ? 148.462 128.424 197.754 1.00 84.05  ? 323 THR A CA  1 
ATOM   2325  C  C   . THR A 1 323 ? 149.407 127.698 196.806 1.00 84.05  ? 323 THR A C   1 
ATOM   2326  O  O   . THR A 1 323 ? 149.021 126.675 196.233 1.00 84.05  ? 323 THR A O   1 
ATOM   2327  C  CB  . THR A 1 323 ? 147.018 128.270 197.264 1.00 84.05  ? 323 THR A CB  1 
ATOM   2328  O  OG1 . THR A 1 323 ? 146.883 128.869 195.970 1.00 84.05  ? 323 THR A OG1 1 
ATOM   2329  C  CG2 . THR A 1 323 ? 146.055 128.945 198.231 1.00 84.05  ? 323 THR A CG2 1 
ATOM   2330  N  N   . VAL A 1 324 ? 150.617 128.230 196.604 1.00 83.72  ? 324 VAL A N   1 
ATOM   2331  C  CA  . VAL A 1 324 ? 151.704 127.580 195.873 1.00 83.72  ? 324 VAL A CA  1 
ATOM   2332  C  C   . VAL A 1 324 ? 151.420 127.511 194.376 1.00 83.72  ? 324 VAL A C   1 
ATOM   2333  O  O   . VAL A 1 324 ? 152.318 127.733 193.555 1.00 83.72  ? 324 VAL A O   1 
ATOM   2334  C  CB  . VAL A 1 324 ? 151.987 126.173 196.439 1.00 83.72  ? 324 VAL A CB  1 
ATOM   2335  C  CG1 . VAL A 1 324 ? 153.044 125.460 195.609 1.00 83.72  ? 324 VAL A CG1 1 
ATOM   2336  C  CG2 . VAL A 1 324 ? 152.417 126.262 197.896 1.00 83.72  ? 324 VAL A CG2 1 
ATOM   2337  N  N   . ASP A 1 325 ? 150.175 127.222 194.008 1.00 84.47  ? 325 ASP A N   1 
ATOM   2338  C  CA  . ASP A 1 325 ? 149.839 126.832 192.646 1.00 84.47  ? 325 ASP A CA  1 
ATOM   2339  C  C   . ASP A 1 325 ? 149.827 128.044 191.725 1.00 84.47  ? 325 ASP A C   1 
ATOM   2340  O  O   . ASP A 1 325 ? 149.549 129.171 192.139 1.00 84.47  ? 325 ASP A O   1 
ATOM   2341  C  CB  . ASP A 1 325 ? 148.484 126.114 192.587 1.00 84.47  ? 325 ASP A CB  1 
ATOM   2342  C  CG  . ASP A 1 325 ? 148.527 124.740 193.223 1.00 84.47  ? 325 ASP A CG  1 
ATOM   2343  O  OD1 . ASP A 1 325 ? 149.607 124.113 193.208 1.00 84.47  ? 325 ASP A OD1 1 
ATOM   2344  O  OD2 . ASP A 1 325 ? 147.484 124.286 193.738 1.00 84.47  ? 325 ASP A OD2 1 
ATOM   2345  N  N   . TRP A 1 326 ? 150.139 127.785 190.458 1.00 81.81  ? 326 TRP A N   1 
ATOM   2346  C  CA  . TRP A 1 326 ? 150.043 128.765 189.388 1.00 81.81  ? 326 TRP A CA  1 
ATOM   2347  C  C   . TRP A 1 326 ? 148.594 128.841 188.923 1.00 81.81  ? 326 TRP A C   1 
ATOM   2348  O  O   . TRP A 1 326 ? 147.762 128.027 189.335 1.00 81.81  ? 326 TRP A O   1 
ATOM   2349  C  CB  . TRP A 1 326 ? 150.955 128.376 188.221 1.00 81.81  ? 326 TRP A CB  1 
ATOM   2350  C  CG  . TRP A 1 326 ? 152.417 128.382 188.570 1.00 81.81  ? 326 TRP A CG  1 
ATOM   2351  C  CD1 . TRP A 1 326 ? 153.137 127.343 189.082 1.00 81.81  ? 326 TRP A CD1 1 
ATOM   2352  C  CD2 . TRP A 1 326 ? 153.347 129.458 188.385 1.00 81.81  ? 326 TRP A CD2 1 
ATOM   2353  N  NE1 . TRP A 1 326 ? 154.447 127.713 189.256 1.00 81.81  ? 326 TRP A NE1 1 
ATOM   2354  C  CE2 . TRP A 1 326 ? 154.604 129.006 188.832 1.00 81.81  ? 326 TRP A CE2 1 
ATOM   2355  C  CE3 . TRP A 1 326 ? 153.238 130.761 187.892 1.00 81.81  ? 326 TRP A CE3 1 
ATOM   2356  C  CZ2 . TRP A 1 326 ? 155.740 129.810 188.802 1.00 81.81  ? 326 TRP A CZ2 1 
ATOM   2357  C  CZ3 . TRP A 1 326 ? 154.367 131.558 187.866 1.00 81.81  ? 326 TRP A CZ3 1 
ATOM   2358  C  CH2 . TRP A 1 326 ? 155.601 131.080 188.318 1.00 81.81  ? 326 TRP A CH2 1 
ATOM   2359  N  N   . GLU A 1 327 ? 148.289 129.815 188.070 1.00 81.01  ? 327 GLU A N   1 
ATOM   2360  C  CA  . GLU A 1 327 ? 146.953 129.964 187.510 1.00 81.01  ? 327 GLU A CA  1 
ATOM   2361  C  C   . GLU A 1 327 ? 147.027 130.303 186.029 1.00 81.01  ? 327 GLU A C   1 
ATOM   2362  O  O   . GLU A 1 327 ? 148.093 130.651 185.509 1.00 81.01  ? 327 GLU A O   1 
ATOM   2363  C  CB  . GLU A 1 327 ? 146.149 131.040 188.243 1.00 81.01  ? 327 GLU A CB  1 
ATOM   2364  C  CG  . GLU A 1 327 ? 145.797 130.689 189.675 1.00 81.01  ? 327 GLU A CG  1 
ATOM   2365  C  CD  . GLU A 1 327 ? 144.893 131.719 190.316 1.00 81.01  ? 327 GLU A CD  1 
ATOM   2366  O  OE1 . GLU A 1 327 ? 144.594 132.740 189.662 1.00 81.01  ? 327 GLU A OE1 1 
ATOM   2367  O  OE2 . GLU A 1 327 ? 144.483 131.512 191.477 1.00 81.01  ? 327 GLU A OE2 1 
ATOM   2368  N  N   . TRP A 1 328 ? 145.877 130.215 185.366 1.00 90.62  ? 328 TRP A N   1 
ATOM   2369  C  CA  . TRP A 1 328 ? 145.794 130.392 183.924 1.00 90.62  ? 328 TRP A CA  1 
ATOM   2370  C  C   . TRP A 1 328 ? 145.183 131.747 183.581 1.00 90.62  ? 328 TRP A C   1 
ATOM   2371  O  O   . TRP A 1 328 ? 144.357 132.288 184.321 1.00 90.62  ? 328 TRP A O   1 
ATOM   2372  C  CB  . TRP A 1 328 ? 144.954 129.270 183.316 1.00 90.62  ? 328 TRP A CB  1 
ATOM   2373  C  CG  . TRP A 1 328 ? 144.868 129.289 181.825 1.00 90.62  ? 328 TRP A CG  1 
ATOM   2374  C  CD1 . TRP A 1 328 ? 143.843 129.778 181.070 1.00 90.62  ? 328 TRP A CD1 1 
ATOM   2375  C  CD2 . TRP A 1 328 ? 145.830 128.763 180.904 1.00 90.62  ? 328 TRP A CD2 1 
ATOM   2376  N  NE1 . TRP A 1 328 ? 144.114 129.606 179.735 1.00 90.62  ? 328 TRP A NE1 1 
ATOM   2377  C  CE2 . TRP A 1 328 ? 145.328 128.984 179.606 1.00 90.62  ? 328 TRP A CE2 1 
ATOM   2378  C  CE3 . TRP A 1 328 ? 147.070 128.135 181.050 1.00 90.62  ? 328 TRP A CE3 1 
ATOM   2379  C  CZ2 . TRP A 1 328 ? 146.023 128.598 178.463 1.00 90.62  ? 328 TRP A CZ2 1 
ATOM   2380  C  CZ3 . TRP A 1 328 ? 147.758 127.754 179.914 1.00 90.62  ? 328 TRP A CZ3 1 
ATOM   2381  C  CH2 . TRP A 1 328 ? 147.231 127.984 178.638 1.00 90.62  ? 328 TRP A CH2 1 
ATOM   2382  N  N   . CYS A 1 329 ? 145.592 132.294 182.437 1.00 85.32  ? 329 CYS A N   1 
ATOM   2383  C  CA  . CYS A 1 329 ? 145.082 133.573 181.962 1.00 85.32  ? 329 CYS A CA  1 
ATOM   2384  C  C   . CYS A 1 329 ? 144.929 133.526 180.448 1.00 85.32  ? 329 CYS A C   1 
ATOM   2385  O  O   . CYS A 1 329 ? 145.113 132.485 179.812 1.00 85.32  ? 329 CYS A O   1 
ATOM   2386  C  CB  . CYS A 1 329 ? 145.993 134.736 182.375 1.00 85.32  ? 329 CYS A CB  1 
ATOM   2387  S  SG  . CYS A 1 329 ? 146.034 135.064 184.152 1.00 85.32  ? 329 CYS A SG  1 
ATOM   2388  N  N   . ALA A 1 330 ? 144.594 134.676 179.873 1.00 78.70  ? 330 ALA A N   1 
ATOM   2389  C  CA  . ALA A 1 330 ? 144.329 134.744 178.444 1.00 78.70  ? 330 ALA A CA  1 
ATOM   2390  C  C   . ALA A 1 330 ? 145.639 134.737 177.658 1.00 78.70  ? 330 ALA A C   1 
ATOM   2391  O  O   . ALA A 1 330 ? 146.654 135.253 178.135 1.00 78.70  ? 330 ALA A O   1 
ATOM   2392  C  CB  . ALA A 1 330 ? 143.525 135.999 178.110 1.00 78.70  ? 330 ALA A CB  1 
ATOM   2393  N  N   . PRO A 1 331 ? 145.651 134.160 176.461 1.00 79.81  ? 331 PRO A N   1 
ATOM   2394  C  CA  . PRO A 1 331 ? 146.868 134.164 175.646 1.00 79.81  ? 331 PRO A CA  1 
ATOM   2395  C  C   . PRO A 1 331 ? 147.074 135.497 174.941 1.00 79.81  ? 331 PRO A C   1 
ATOM   2396  O  O   . PRO A 1 331 ? 146.217 136.382 174.949 1.00 79.81  ? 331 PRO A O   1 
ATOM   2397  C  CB  . PRO A 1 331 ? 146.615 133.042 174.633 1.00 79.81  ? 331 PRO A CB  1 
ATOM   2398  C  CG  . PRO A 1 331 ? 145.132 133.002 174.502 1.00 79.81  ? 331 PRO A CG  1 
ATOM   2399  C  CD  . PRO A 1 331 ? 144.584 133.341 175.861 1.00 79.81  ? 331 PRO A CD  1 
ATOM   2400  N  N   . LEU A 1 332 ? 148.243 135.621 174.318 1.00 75.14  ? 332 LEU A N   1 
ATOM   2401  C  CA  . LEU A 1 332 ? 148.575 136.834 173.592 1.00 75.14  ? 332 LEU A CA  1 
ATOM   2402  C  C   . LEU A 1 332 ? 147.853 136.863 172.245 1.00 75.14  ? 332 LEU A C   1 
ATOM   2403  O  O   . LEU A 1 332 ? 147.650 135.820 171.618 1.00 75.14  ? 332 LEU A O   1 
ATOM   2404  C  CB  . LEU A 1 332 ? 150.081 136.928 173.362 1.00 75.14  ? 332 LEU A CB  1 
ATOM   2405  C  CG  . LEU A 1 332 ? 151.009 137.055 174.570 1.00 75.14  ? 332 LEU A CG  1 
ATOM   2406  C  CD1 . LEU A 1 332 ? 152.455 137.007 174.119 1.00 75.14  ? 332 LEU A CD1 1 
ATOM   2407  C  CD2 . LEU A 1 332 ? 150.734 138.332 175.330 1.00 75.14  ? 332 LEU A CD2 1 
ATOM   2408  N  N   . PRO A 1 333 ? 147.458 138.050 171.775 1.00 74.70  ? 333 PRO A N   1 
ATOM   2409  C  CA  . PRO A 1 333 ? 146.835 138.128 170.443 1.00 74.70  ? 333 PRO A CA  1 
ATOM   2410  C  C   . PRO A 1 333 ? 147.781 137.758 169.316 1.00 74.70  ? 333 PRO A C   1 
ATOM   2411  O  O   . PRO A 1 333 ? 147.341 137.597 168.171 1.00 74.70  ? 333 PRO A O   1 
ATOM   2412  C  CB  . PRO A 1 333 ? 146.391 139.595 170.349 1.00 74.70  ? 333 PRO A CB  1 
ATOM   2413  C  CG  . PRO A 1 333 ? 146.285 140.052 171.759 1.00 74.70  ? 333 PRO A CG  1 
ATOM   2414  C  CD  . PRO A 1 333 ? 147.374 139.330 172.495 1.00 74.70  ? 333 PRO A CD  1 
ATOM   2415  N  N   . ARG A 1 334 ? 149.073 137.626 169.605 1.00 78.34  ? 334 ARG A N   1 
ATOM   2416  C  CA  . ARG A 1 334 ? 150.059 137.251 168.605 1.00 78.34  ? 334 ARG A CA  1 
ATOM   2417  C  C   . ARG A 1 334 ? 151.203 136.511 169.281 1.00 78.34  ? 334 ARG A C   1 
ATOM   2418  O  O   . ARG A 1 334 ? 151.127 136.169 170.463 1.00 78.34  ? 334 ARG A O   1 
ATOM   2419  C  CB  . ARG A 1 334 ? 150.578 138.476 167.843 1.00 78.34  ? 334 ARG A CB  1 
ATOM   2420  C  CG  . ARG A 1 334 ? 151.343 139.476 168.693 1.00 78.34  ? 334 ARG A CG  1 
ATOM   2421  C  CD  . ARG A 1 334 ? 151.694 140.697 167.863 1.00 78.34  ? 334 ARG A CD  1 
ATOM   2422  N  NE  . ARG A 1 334 ? 150.504 141.463 167.508 1.00 78.34  ? 334 ARG A NE  1 
ATOM   2423  C  CZ  . ARG A 1 334 ? 150.483 142.434 166.601 1.00 78.34  ? 334 ARG A CZ  1 
ATOM   2424  N  NH1 . ARG A 1 334 ? 151.588 142.751 165.941 1.00 78.34  ? 334 ARG A NH1 1 
ATOM   2425  N  NH2 . ARG A 1 334 ? 149.353 143.078 166.343 1.00 78.34  ? 334 ARG A NH2 1 
ATOM   2426  N  N   . ASP A 1 335 ? 152.262 136.259 168.517 1.00 82.88  ? 335 ASP A N   1 
ATOM   2427  C  CA  . ASP A 1 335 ? 153.392 135.498 169.027 1.00 82.88  ? 335 ASP A CA  1 
ATOM   2428  C  C   . ASP A 1 335 ? 154.701 136.202 168.703 1.00 82.88  ? 335 ASP A C   1 
ATOM   2429  O  O   . ASP A 1 335 ? 155.026 136.434 167.535 1.00 82.88  ? 335 ASP A O   1 
ATOM   2430  C  CB  . ASP A 1 335 ? 153.393 134.090 168.434 1.00 82.88  ? 335 ASP A CB  1 
ATOM   2431  C  CG  . ASP A 1 335 ? 154.436 133.195 169.065 1.00 82.88  ? 335 ASP A CG  1 
ATOM   2432  O  OD1 . ASP A 1 335 ? 154.221 132.754 170.212 1.00 82.88  ? 335 ASP A OD1 1 
ATOM   2433  O  OD2 . ASP A 1 335 ? 155.470 132.933 168.416 1.00 82.88  ? 335 ASP A OD2 1 
ATOM   2434  N  N   . ARG A 1 336 ? 155.455 136.543 169.746 1.00 68.39  ? 336 ARG A N   1 
ATOM   2435  C  CA  . ARG A 1 336 ? 156.725 137.233 169.583 1.00 68.39  ? 336 ARG A CA  1 
ATOM   2436  C  C   . ARG A 1 336 ? 157.771 136.612 170.497 1.00 68.39  ? 336 ARG A C   1 
ATOM   2437  O  O   . ARG A 1 336 ? 157.474 135.743 171.319 1.00 68.39  ? 336 ARG A O   1 
ATOM   2438  C  CB  . ARG A 1 336 ? 156.594 138.736 169.864 1.00 68.39  ? 336 ARG A CB  1 
ATOM   2439  C  CG  . ARG A 1 336 ? 155.770 139.482 168.827 1.00 68.39  ? 336 ARG A CG  1 
ATOM   2440  C  CD  . ARG A 1 336 ? 155.654 140.959 169.154 1.00 68.39  ? 336 ARG A CD  1 
ATOM   2441  N  NE  . ARG A 1 336 ? 154.849 141.197 170.347 1.00 68.39  ? 336 ARG A NE  1 
ATOM   2442  C  CZ  . ARG A 1 336 ? 154.694 142.387 170.915 1.00 68.39  ? 336 ARG A CZ  1 
ATOM   2443  N  NH1 . ARG A 1 336 ? 155.289 143.453 170.399 1.00 68.39  ? 336 ARG A NH1 1 
ATOM   2444  N  NH2 . ARG A 1 336 ? 153.943 142.512 172.000 1.00 68.39  ? 336 ARG A NH2 1 
ATOM   2445  N  N   . LEU A 1 337 ? 159.009 137.071 170.336 1.00 70.45  ? 337 LEU A N   1 
ATOM   2446  C  CA  . LEU A 1 337 ? 160.156 136.557 171.069 1.00 70.45  ? 337 LEU A CA  1 
ATOM   2447  C  C   . LEU A 1 337 ? 160.938 137.710 171.680 1.00 70.45  ? 337 LEU A C   1 
ATOM   2448  O  O   . LEU A 1 337 ? 161.152 138.739 171.031 1.00 70.45  ? 337 LEU A O   1 
ATOM   2449  C  CB  . LEU A 1 337 ? 161.069 135.733 170.152 1.00 70.45  ? 337 LEU A CB  1 
ATOM   2450  C  CG  . LEU A 1 337 ? 162.338 135.126 170.756 1.00 70.45  ? 337 LEU A CG  1 
ATOM   2451  C  CD1 . LEU A 1 337 ? 162.011 134.127 171.850 1.00 70.45  ? 337 LEU A CD1 1 
ATOM   2452  C  CD2 . LEU A 1 337 ? 163.185 134.477 169.672 1.00 70.45  ? 337 LEU A CD2 1 
ATOM   2453  N  N   . GLN A 1 338 ? 161.362 137.529 172.933 1.00 64.32  ? 338 GLN A N   1 
ATOM   2454  C  CA  . GLN A 1 338 ? 162.151 138.522 173.665 1.00 64.32  ? 338 GLN A CA  1 
ATOM   2455  C  C   . GLN A 1 338 ? 161.419 139.856 173.789 1.00 64.32  ? 338 GLN A C   1 
ATOM   2456  O  O   . GLN A 1 338 ? 162.044 140.918 173.820 1.00 64.32  ? 338 GLN A O   1 
ATOM   2457  C  CB  . GLN A 1 338 ? 163.526 138.726 173.025 1.00 64.32  ? 338 GLN A CB  1 
ATOM   2458  C  CG  . GLN A 1 338 ? 164.432 137.512 173.114 1.00 64.32  ? 338 GLN A CG  1 
ATOM   2459  C  CD  . GLN A 1 338 ? 165.783 137.743 172.471 1.00 64.32  ? 338 GLN A CD  1 
ATOM   2460  O  OE1 . GLN A 1 338 ? 166.038 138.802 171.899 1.00 64.32  ? 338 GLN A OE1 1 
ATOM   2461  N  NE2 . GLN A 1 338 ? 166.658 136.749 172.562 1.00 64.32  ? 338 GLN A NE2 1 
ATOM   2462  N  N   . HIS A 1 339 ? 160.093 139.811 173.861 1.00 58.61  ? 339 HIS A N   1 
ATOM   2463  C  CA  . HIS A 1 339 ? 159.305 141.012 174.075 1.00 58.61  ? 339 HIS A CA  1 
ATOM   2464  C  C   . HIS A 1 339 ? 159.491 141.521 175.502 1.00 58.61  ? 339 HIS A C   1 
ATOM   2465  O  O   . HIS A 1 339 ? 159.974 140.810 176.386 1.00 58.61  ? 339 HIS A O   1 
ATOM   2466  C  CB  . HIS A 1 339 ? 157.828 140.739 173.791 1.00 58.61  ? 339 HIS A CB  1 
ATOM   2467  C  CG  . HIS A 1 339 ? 157.221 139.706 174.688 1.00 58.61  ? 339 HIS A CG  1 
ATOM   2468  N  ND1 . HIS A 1 339 ? 157.396 138.354 174.489 1.00 58.61  ? 339 HIS A ND1 1 
ATOM   2469  C  CD2 . HIS A 1 339 ? 156.432 139.825 175.781 1.00 58.61  ? 339 HIS A CD2 1 
ATOM   2470  C  CE1 . HIS A 1 339 ? 156.748 137.685 175.425 1.00 58.61  ? 339 HIS A CE1 1 
ATOM   2471  N  NE2 . HIS A 1 339 ? 156.153 138.554 176.221 1.00 58.61  ? 339 HIS A NE2 1 
ATOM   2472  N  N   . THR A 1 340 ? 159.099 142.773 175.718 1.00 48.75  ? 340 THR A N   1 
ATOM   2473  C  CA  . THR A 1 340 ? 159.285 143.440 177.001 1.00 48.75  ? 340 THR A CA  1 
ATOM   2474  C  C   . THR A 1 340 ? 157.936 143.623 177.684 1.00 48.75  ? 340 THR A C   1 
ATOM   2475  O  O   . THR A 1 340 ? 157.052 144.301 177.149 1.00 48.75  ? 340 THR A O   1 
ATOM   2476  C  CB  . THR A 1 340 ? 159.973 144.791 176.812 1.00 48.75  ? 340 THR A CB  1 
ATOM   2477  O  OG1 . THR A 1 340 ? 161.255 144.594 176.205 1.00 48.75  ? 340 THR A OG1 1 
ATOM   2478  C  CG2 . THR A 1 340 ? 160.156 145.483 178.149 1.00 48.75  ? 340 THR A CG2 1 
ATOM   2479  N  N   . LEU A 1 341 ? 157.780 143.019 178.859 1.00 44.77  ? 341 LEU A N   1 
ATOM   2480  C  CA  . LEU A 1 341 ? 156.592 143.199 179.685 1.00 44.77  ? 341 LEU A CA  1 
ATOM   2481  C  C   . LEU A 1 341 ? 156.865 144.288 180.713 1.00 44.77  ? 341 LEU A C   1 
ATOM   2482  O  O   . LEU A 1 341 ? 157.802 144.173 181.510 1.00 44.77  ? 341 LEU A O   1 
ATOM   2483  C  CB  . LEU A 1 341 ? 156.193 141.900 180.384 1.00 44.77  ? 341 LEU A CB  1 
ATOM   2484  C  CG  . LEU A 1 341 ? 155.627 140.768 179.529 1.00 44.77  ? 341 LEU A CG  1 
ATOM   2485  C  CD1 . LEU A 1 341 ? 155.425 139.526 180.374 1.00 44.77  ? 341 LEU A CD1 1 
ATOM   2486  C  CD2 . LEU A 1 341 ? 154.320 141.190 178.880 1.00 44.77  ? 341 LEU A CD2 1 
ATOM   2487  N  N   . VAL A 1 342 ? 156.048 145.337 180.694 1.00 39.73  ? 342 VAL A N   1 
ATOM   2488  C  CA  . VAL A 1 342 ? 156.131 146.434 181.648 1.00 39.73  ? 342 VAL A CA  1 
ATOM   2489  C  C   . VAL A 1 342 ? 154.806 146.517 182.391 1.00 39.73  ? 342 VAL A C   1 
ATOM   2490  O  O   . VAL A 1 342 ? 153.748 146.683 181.771 1.00 39.73  ? 342 VAL A O   1 
ATOM   2491  C  CB  . VAL A 1 342 ? 156.452 147.770 180.956 1.00 39.73  ? 342 VAL A CB  1 
ATOM   2492  C  CG1 . VAL A 1 342 ? 156.444 148.896 181.965 1.00 39.73  ? 342 VAL A CG1 1 
ATOM   2493  C  CG2 . VAL A 1 342 ? 157.793 147.694 180.251 1.00 39.73  ? 342 VAL A CG2 1 
ATOM   2494  N  N   . SER A 1 343 ? 154.864 146.395 183.713 1.00 44.00  ? 343 SER A N   1 
ATOM   2495  C  CA  . SER A 1 343 ? 153.677 146.455 184.552 1.00 44.00  ? 343 SER A CA  1 
ATOM   2496  C  C   . SER A 1 343 ? 153.289 147.901 184.820 1.00 44.00  ? 343 SER A C   1 
ATOM   2497  O  O   . SER A 1 343 ? 154.139 148.736 185.139 1.00 44.00  ? 343 SER A O   1 
ATOM   2498  C  CB  . SER A 1 343 ? 153.917 145.728 185.875 1.00 44.00  ? 343 SER A CB  1 
ATOM   2499  O  OG  . SER A 1 343 ? 152.788 145.829 186.722 1.00 44.00  ? 343 SER A OG  1 
ATOM   2500  N  N   . VAL A 1 344 ? 151.999 148.191 184.690 1.00 49.92  ? 344 VAL A N   1 
ATOM   2501  C  CA  . VAL A 1 344 ? 151.479 149.531 184.951 1.00 49.92  ? 344 VAL A CA  1 
ATOM   2502  C  C   . VAL A 1 344 ? 150.393 149.436 186.016 1.00 49.92  ? 344 VAL A C   1 
ATOM   2503  O  O   . VAL A 1 344 ? 149.235 149.123 185.698 1.00 49.92  ? 344 VAL A O   1 
ATOM   2504  C  CB  . VAL A 1 344 ? 150.948 150.187 183.668 1.00 49.92  ? 344 VAL A CB  1 
ATOM   2505  C  CG1 . VAL A 1 344 ? 150.344 151.545 183.978 1.00 49.92  ? 344 VAL A CG1 1 
ATOM   2506  C  CG2 . VAL A 1 344 ? 152.056 150.322 182.646 1.00 49.92  ? 344 VAL A CG2 1 
ATOM   2507  N  N   . PRO A 1 345 ? 150.723 149.666 187.288 1.00 56.44  ? 345 PRO A N   1 
ATOM   2508  C  CA  . PRO A 1 345 ? 149.681 149.672 188.325 1.00 56.44  ? 345 PRO A CA  1 
ATOM   2509  C  C   . PRO A 1 345 ? 148.774 150.884 188.261 1.00 56.44  ? 345 PRO A C   1 
ATOM   2510  O  O   . PRO A 1 345 ? 147.722 150.884 188.912 1.00 56.44  ? 345 PRO A O   1 
ATOM   2511  C  CB  . PRO A 1 345 ? 150.485 149.650 189.632 1.00 56.44  ? 345 PRO A CB  1 
ATOM   2512  C  CG  . PRO A 1 345 ? 151.830 149.119 189.247 1.00 56.44  ? 345 PRO A CG  1 
ATOM   2513  C  CD  . PRO A 1 345 ? 152.073 149.651 187.869 1.00 56.44  ? 345 PRO A CD  1 
ATOM   2514  N  N   . GLY A 1 346 ? 149.149 151.923 187.511 1.00 58.60  ? 346 GLY A N   1 
ATOM   2515  C  CA  . GLY A 1 346 ? 148.280 153.082 187.389 1.00 58.60  ? 346 GLY A CA  1 
ATOM   2516  C  C   . GLY A 1 346 ? 146.963 152.744 186.719 1.00 58.60  ? 346 GLY A C   1 
ATOM   2517  O  O   . GLY A 1 346 ? 145.893 152.873 187.319 1.00 58.60  ? 346 GLY A O   1 
ATOM   2518  N  N   . LYS A 1 347 ? 147.025 152.297 185.468 1.00 58.28  ? 347 LYS A N   1 
ATOM   2519  C  CA  . LYS A 1 347 ? 145.845 151.864 184.736 1.00 58.28  ? 347 LYS A CA  1 
ATOM   2520  C  C   . LYS A 1 347 ? 145.464 150.422 185.037 1.00 58.28  ? 347 LYS A C   1 
ATOM   2521  O  O   . LYS A 1 347 ? 144.511 149.912 184.439 1.00 58.28  ? 347 LYS A O   1 
ATOM   2522  C  CB  . LYS A 1 347 ? 146.066 152.034 183.230 1.00 58.28  ? 347 LYS A CB  1 
ATOM   2523  C  CG  . LYS A 1 347 ? 146.099 153.481 182.767 1.00 58.28  ? 347 LYS A CG  1 
ATOM   2524  C  CD  . LYS A 1 347 ? 146.452 153.591 181.291 1.00 58.28  ? 347 LYS A CD  1 
ATOM   2525  C  CE  . LYS A 1 347 ? 145.209 153.600 180.412 1.00 58.28  ? 347 LYS A CE  1 
ATOM   2526  N  NZ  . LYS A 1 347 ? 144.534 152.274 180.357 1.00 58.28  ? 347 LYS A NZ  1 
ATOM   2527  N  N   . ASP A 1 348 ? 146.176 149.762 185.951 1.00 58.38  ? 348 ASP A N   1 
ATOM   2528  C  CA  . ASP A 1 348 ? 145.969 148.347 186.258 1.00 58.38  ? 348 ASP A CA  1 
ATOM   2529  C  C   . ASP A 1 348 ? 146.035 147.502 184.989 1.00 58.38  ? 348 ASP A C   1 
ATOM   2530  O  O   . ASP A 1 348 ? 145.084 146.813 184.616 1.00 58.38  ? 348 ASP A O   1 
ATOM   2531  C  CB  . ASP A 1 348 ? 144.648 148.127 186.997 1.00 58.38  ? 348 ASP A CB  1 
ATOM   2532  C  CG  . ASP A 1 348 ? 144.672 148.674 188.411 1.00 58.38  ? 348 ASP A CG  1 
ATOM   2533  O  OD1 . ASP A 1 348 ? 145.764 148.709 189.015 1.00 58.38  ? 348 ASP A OD1 1 
ATOM   2534  O  OD2 . ASP A 1 348 ? 143.602 149.067 188.921 1.00 58.38  ? 348 ASP A OD2 1 
ATOM   2535  N  N   . ALA A 1 349 ? 147.183 147.562 184.316 1.00 53.25  ? 349 ALA A N   1 
ATOM   2536  C  CA  . ALA A 1 349 ? 147.380 146.846 183.067 1.00 53.25  ? 349 ALA A CA  1 
ATOM   2537  C  C   . ALA A 1 349 ? 148.839 146.438 182.939 1.00 53.25  ? 349 ALA A C   1 
ATOM   2538  O  O   . ALA A 1 349 ? 149.657 146.725 183.816 1.00 53.25  ? 349 ALA A O   1 
ATOM   2539  C  CB  . ALA A 1 349 ? 146.965 147.695 181.860 1.00 53.25  ? 349 ALA A CB  1 
ATOM   2540  N  N   . ILE A 1 350 ? 149.153 145.756 181.840 1.00 47.32  ? 350 ILE A N   1 
ATOM   2541  C  CA  . ILE A 1 350 ? 150.521 145.371 181.503 1.00 47.32  ? 350 ILE A CA  1 
ATOM   2542  C  C   . ILE A 1 350 ? 150.721 145.590 180.014 1.00 47.32  ? 350 ILE A C   1 
ATOM   2543  O  O   . ILE A 1 350 ? 149.952 145.067 179.198 1.00 47.32  ? 350 ILE A O   1 
ATOM   2544  C  CB  . ILE A 1 350 ? 150.820 143.911 181.871 1.00 47.32  ? 350 ILE A CB  1 
ATOM   2545  C  CG1 . ILE A 1 350 ? 150.831 143.725 183.382 1.00 47.32  ? 350 ILE A CG1 1 
ATOM   2546  C  CG2 . ILE A 1 350 ? 152.138 143.466 181.270 1.00 47.32  ? 350 ILE A CG2 1 
ATOM   2547  C  CD1 . ILE A 1 350 ? 150.975 142.303 183.782 1.00 47.32  ? 350 ILE A CD1 1 
ATOM   2548  N  N   . TYR A 1 351 ? 151.755 146.344 179.654 1.00 49.55  ? 351 TYR A N   1 
ATOM   2549  C  CA  . TYR A 1 351 ? 152.069 146.580 178.252 1.00 49.55  ? 351 TYR A CA  1 
ATOM   2550  C  C   . TYR A 1 351 ? 153.162 145.618 177.812 1.00 49.55  ? 351 TYR A C   1 
ATOM   2551  O  O   . TYR A 1 351 ? 154.107 145.362 178.562 1.00 49.55  ? 351 TYR A O   1 
ATOM   2552  C  CB  . TYR A 1 351 ? 152.515 148.022 177.993 1.00 49.55  ? 351 TYR A CB  1 
ATOM   2553  C  CG  . TYR A 1 351 ? 151.454 149.083 178.210 1.00 49.55  ? 351 TYR A CG  1 
ATOM   2554  C  CD1 . TYR A 1 351 ? 150.182 148.750 178.640 1.00 49.55  ? 351 TYR A CD1 1 
ATOM   2555  C  CD2 . TYR A 1 351 ? 151.708 150.412 177.905 1.00 49.55  ? 351 TYR A CD2 1 
ATOM   2556  C  CE1 . TYR A 1 351 ? 149.210 149.712 178.817 1.00 49.55  ? 351 TYR A CE1 1 
ATOM   2557  C  CE2 . TYR A 1 351 ? 150.743 151.381 178.077 1.00 49.55  ? 351 TYR A CE2 1 
ATOM   2558  C  CZ  . TYR A 1 351 ? 149.494 151.025 178.531 1.00 49.55  ? 351 TYR A CZ  1 
ATOM   2559  O  OH  . TYR A 1 351 ? 148.526 151.986 178.700 1.00 49.55  ? 351 TYR A OH  1 
ATOM   2560  N  N   . SER A 1 352 ? 153.028 145.086 176.603 1.00 50.45  ? 352 SER A N   1 
ATOM   2561  C  CA  . SER A 1 352 ? 154.065 144.278 175.977 1.00 50.45  ? 352 SER A CA  1 
ATOM   2562  C  C   . SER A 1 352 ? 154.557 144.999 174.732 1.00 50.45  ? 352 SER A C   1 
ATOM   2563  O  O   . SER A 1 352 ? 153.752 145.381 173.872 1.00 50.45  ? 352 SER A O   1 
ATOM   2564  C  CB  . SER A 1 352 ? 153.549 142.885 175.620 1.00 50.45  ? 352 SER A CB  1 
ATOM   2565  O  OG  . SER A 1 352 ? 154.558 142.123 174.984 1.00 50.45  ? 352 SER A OG  1 
ATOM   2566  N  N   . LEU A 1 353 ? 155.874 145.183 174.644 1.00 50.25  ? 353 LEU A N   1 
ATOM   2567  C  CA  . LEU A 1 353 ? 156.494 146.033 173.640 1.00 50.25  ? 353 LEU A CA  1 
ATOM   2568  C  C   . LEU A 1 353 ? 157.566 145.261 172.886 1.00 50.25  ? 353 LEU A C   1 
ATOM   2569  O  O   . LEU A 1 353 ? 158.299 144.461 173.477 1.00 50.25  ? 353 LEU A O   1 
ATOM   2570  C  CB  . LEU A 1 353 ? 157.130 147.276 174.281 1.00 50.25  ? 353 LEU A CB  1 
ATOM   2571  C  CG  . LEU A 1 353 ? 156.253 148.423 174.786 1.00 50.25  ? 353 LEU A CG  1 
ATOM   2572  C  CD1 . LEU A 1 353 ? 155.567 148.054 176.086 1.00 50.25  ? 353 LEU A CD1 1 
ATOM   2573  C  CD2 . LEU A 1 353 ? 157.081 149.683 174.962 1.00 50.25  ? 353 LEU A CD2 1 
ATOM   2574  N  N   . GLY A 1 354 ? 157.653 145.513 171.580 1.00 55.72  ? 354 GLY A N   1 
ATOM   2575  C  CA  . GLY A 1 354 ? 158.731 145.028 170.739 1.00 55.72  ? 354 GLY A CA  1 
ATOM   2576  C  C   . GLY A 1 354 ? 158.912 143.517 170.743 1.00 55.72  ? 354 GLY A C   1 
ATOM   2577  O  O   . GLY A 1 354 ? 158.083 142.752 171.241 1.00 55.72  ? 354 GLY A O   1 
ATOM   2578  N  N   . GLY A 1 355 ? 160.026 143.095 170.162 1.00 59.38  ? 355 GLY A N   1 
ATOM   2579  C  CA  . GLY A 1 355 ? 160.407 141.700 170.111 1.00 59.38  ? 355 GLY A CA  1 
ATOM   2580  C  C   . GLY A 1 355 ? 160.447 141.170 168.691 1.00 59.38  ? 355 GLY A C   1 
ATOM   2581  O  O   . GLY A 1 355 ? 159.883 141.745 167.762 1.00 59.38  ? 355 GLY A O   1 
ATOM   2582  N  N   . LYS A 1 356 ? 161.142 140.045 168.542 1.00 69.03  ? 356 LYS A N   1 
ATOM   2583  C  CA  . LYS A 1 356 ? 161.226 139.321 167.282 1.00 69.03  ? 356 LYS A CA  1 
ATOM   2584  C  C   . LYS A 1 356 ? 159.927 138.562 167.055 1.00 69.03  ? 356 LYS A C   1 
ATOM   2585  O  O   . LYS A 1 356 ? 159.216 138.238 168.010 1.00 69.03  ? 356 LYS A O   1 
ATOM   2586  C  CB  . LYS A 1 356 ? 162.402 138.342 167.284 1.00 69.03  ? 356 LYS A CB  1 
ATOM   2587  C  CG  . LYS A 1 356 ? 163.764 139.004 167.332 1.00 69.03  ? 356 LYS A CG  1 
ATOM   2588  C  CD  . LYS A 1 356 ? 164.875 137.969 167.334 1.00 69.03  ? 356 LYS A CD  1 
ATOM   2589  C  CE  . LYS A 1 356 ? 166.239 138.628 167.420 1.00 69.03  ? 356 LYS A CE  1 
ATOM   2590  N  NZ  . LYS A 1 356 ? 167.335 137.623 167.456 1.00 69.03  ? 356 LYS A NZ  1 
ATOM   2591  N  N   . THR A 1 357 ? 159.620 138.274 165.793 1.00 76.94  ? 357 THR A N   1 
ATOM   2592  C  CA  . THR A 1 357 ? 158.416 137.531 165.422 1.00 76.94  ? 357 THR A CA  1 
ATOM   2593  C  C   . THR A 1 357 ? 158.839 136.251 164.709 1.00 76.94  ? 357 THR A C   1 
ATOM   2594  O  O   . THR A 1 357 ? 158.856 136.198 163.476 1.00 76.94  ? 357 THR A O   1 
ATOM   2595  C  CB  . THR A 1 357 ? 157.497 138.370 164.539 1.00 76.94  ? 357 THR A CB  1 
ATOM   2596  O  OG1 . THR A 1 357 ? 158.196 138.758 163.351 1.00 76.94  ? 357 THR A OG1 1 
ATOM   2597  C  CG2 . THR A 1 357 ? 157.025 139.608 165.277 1.00 76.94  ? 357 THR A CG2 1 
ATOM   2598  N  N   . LEU A 1 358 ? 159.169 135.222 165.491 1.00 83.79  ? 358 LEU A N   1 
ATOM   2599  C  CA  . LEU A 1 358 ? 159.597 133.931 164.962 1.00 83.79  ? 358 LEU A CA  1 
ATOM   2600  C  C   . LEU A 1 358 ? 160.760 134.097 163.993 1.00 83.79  ? 358 LEU A C   1 
ATOM   2601  O  O   . LEU A 1 358 ? 161.919 133.890 164.367 1.00 83.79  ? 358 LEU A O   1 
ATOM   2602  C  CB  . LEU A 1 358 ? 158.425 133.213 164.291 1.00 83.79  ? 358 LEU A CB  1 
ATOM   2603  C  CG  . LEU A 1 358 ? 157.298 132.825 165.251 1.00 83.79  ? 358 LEU A CG  1 
ATOM   2604  C  CD1 . LEU A 1 358 ? 156.123 132.217 164.503 1.00 83.79  ? 358 LEU A CD1 1 
ATOM   2605  C  CD2 . LEU A 1 358 ? 157.812 131.875 166.323 1.00 83.79  ? 358 LEU A CD2 1 
ATOM   2606  N  N   . GLN A 1 359 ? 160.468 134.467 162.748 1.00 81.44  ? 359 GLN A N   1 
ATOM   2607  C  CA  . GLN A 1 359 ? 161.533 134.826 161.828 1.00 81.44  ? 359 GLN A CA  1 
ATOM   2608  C  C   . GLN A 1 359 ? 162.181 136.139 162.267 1.00 81.44  ? 359 GLN A C   1 
ATOM   2609  O  O   . GLN A 1 359 ? 161.530 137.044 162.798 1.00 81.44  ? 359 GLN A O   1 
ATOM   2610  C  CB  . GLN A 1 359 ? 161.003 134.923 160.397 1.00 81.44  ? 359 GLN A CB  1 
ATOM   2611  C  CG  . GLN A 1 359 ? 160.006 136.042 160.159 1.00 81.44  ? 359 GLN A CG  1 
ATOM   2612  C  CD  . GLN A 1 359 ? 158.581 135.621 160.457 1.00 81.44  ? 359 GLN A CD  1 
ATOM   2613  O  OE1 . GLN A 1 359 ? 158.346 134.606 161.112 1.00 81.44  ? 359 GLN A OE1 1 
ATOM   2614  N  NE2 . GLN A 1 359 ? 157.621 136.400 159.976 1.00 81.44  ? 359 GLN A NE2 1 
ATOM   2615  N  N   . ASP A 1 360 ? 163.492 136.235 162.043 1.00 81.92  ? 360 ASP A N   1 
ATOM   2616  C  CA  . ASP A 1 360 ? 164.293 137.335 162.579 1.00 81.92  ? 360 ASP A CA  1 
ATOM   2617  C  C   . ASP A 1 360 ? 163.958 138.655 161.876 1.00 81.92  ? 360 ASP A C   1 
ATOM   2618  O  O   . ASP A 1 360 ? 164.752 139.223 161.127 1.00 81.92  ? 360 ASP A O   1 
ATOM   2619  C  CB  . ASP A 1 360 ? 165.776 137.006 162.465 1.00 81.92  ? 360 ASP A CB  1 
ATOM   2620  C  CG  . ASP A 1 360 ? 166.654 137.971 163.246 1.00 81.92  ? 360 ASP A CG  1 
ATOM   2621  O  OD1 . ASP A 1 360 ? 166.113 138.908 163.871 1.00 81.92  ? 360 ASP A OD1 1 
ATOM   2622  O  OD2 . ASP A 1 360 ? 167.890 137.790 163.234 1.00 81.92  ? 360 ASP A OD2 1 
ATOM   2623  N  N   . THR A 1 361 ? 162.748 139.141 162.139 1.00 72.53  ? 361 THR A N   1 
ATOM   2624  C  CA  . THR A 1 361 ? 162.339 140.483 161.749 1.00 72.53  ? 361 THR A CA  1 
ATOM   2625  C  C   . THR A 1 361 ? 161.762 141.176 162.975 1.00 72.53  ? 361 THR A C   1 
ATOM   2626  O  O   . THR A 1 361 ? 160.890 140.626 163.656 1.00 72.53  ? 361 THR A O   1 
ATOM   2627  C  CB  . THR A 1 361 ? 161.336 140.460 160.580 1.00 72.53  ? 361 THR A CB  1 
ATOM   2628  O  OG1 . THR A 1 361 ? 161.009 141.802 160.194 1.00 72.53  ? 361 THR A OG1 1 
ATOM   2629  C  CG2 . THR A 1 361 ? 160.066 139.693 160.929 1.00 72.53  ? 361 THR A CG2 1 
ATOM   2630  N  N   . LEU A 1 362 ? 162.276 142.364 163.276 1.00 58.71  ? 362 LEU A N   1 
ATOM   2631  C  CA  . LEU A 1 362 ? 161.946 143.052 164.515 1.00 58.71  ? 362 LEU A CA  1 
ATOM   2632  C  C   . LEU A 1 362 ? 160.587 143.725 164.390 1.00 58.71  ? 362 LEU A C   1 
ATOM   2633  O  O   . LEU A 1 362 ? 160.297 144.375 163.381 1.00 58.71  ? 362 LEU A O   1 
ATOM   2634  C  CB  . LEU A 1 362 ? 163.023 144.080 164.861 1.00 58.71  ? 362 LEU A CB  1 
ATOM   2635  C  CG  . LEU A 1 362 ? 164.412 143.491 165.120 1.00 58.71  ? 362 LEU A CG  1 
ATOM   2636  C  CD1 . LEU A 1 362 ? 165.420 144.585 165.394 1.00 58.71  ? 362 LEU A CD1 1 
ATOM   2637  C  CD2 . LEU A 1 362 ? 164.376 142.496 166.257 1.00 58.71  ? 362 LEU A CD2 1 
ATOM   2638  N  N   . SER A 1 363 ? 159.758 143.565 165.415 1.00 58.77  ? 363 SER A N   1 
ATOM   2639  C  CA  . SER A 1 363 ? 158.419 144.128 165.415 1.00 58.77  ? 363 SER A CA  1 
ATOM   2640  C  C   . SER A 1 363 ? 158.351 145.366 166.300 1.00 58.77  ? 363 SER A C   1 
ATOM   2641  O  O   . SER A 1 363 ? 159.292 145.699 167.024 1.00 58.77  ? 363 SER A O   1 
ATOM   2642  C  CB  . SER A 1 363 ? 157.399 143.095 165.890 1.00 58.77  ? 363 SER A CB  1 
ATOM   2643  O  OG  . SER A 1 363 ? 157.618 142.753 167.246 1.00 58.77  ? 363 SER A OG  1 
ATOM   2644  N  N   . ASN A 1 364 ? 157.210 146.044 166.238 1.00 56.28  ? 364 ASN A N   1 
ATOM   2645  C  CA  . ASN A 1 364 ? 156.979 147.268 166.997 1.00 56.28  ? 364 ASN A CA  1 
ATOM   2646  C  C   . ASN A 1 364 ? 155.490 147.430 167.286 1.00 56.28  ? 364 ASN A C   1 
ATOM   2647  O  O   . ASN A 1 364 ? 154.861 148.424 166.923 1.00 56.28  ? 364 ASN A O   1 
ATOM   2648  C  CB  . ASN A 1 364 ? 157.553 148.475 166.255 1.00 56.28  ? 364 ASN A CB  1 
ATOM   2649  C  CG  . ASN A 1 364 ? 156.992 148.628 164.854 1.00 56.28  ? 364 ASN A CG  1 
ATOM   2650  O  OD1 . ASN A 1 364 ? 156.099 147.889 164.442 1.00 56.28  ? 364 ASN A OD1 1 
ATOM   2651  N  ND2 . ASN A 1 364 ? 157.518 149.593 164.113 1.00 56.28  ? 364 ASN A ND2 1 
ATOM   2652  N  N   . ALA A 1 365 ? 154.910 146.442 167.957 1.00 56.01  ? 365 ALA A N   1 
ATOM   2653  C  CA  . ALA A 1 365 ? 153.497 146.456 168.299 1.00 56.01  ? 365 ALA A CA  1 
ATOM   2654  C  C   . ALA A 1 365 ? 153.320 146.356 169.807 1.00 56.01  ? 365 ALA A C   1 
ATOM   2655  O  O   . ALA A 1 365 ? 153.716 145.364 170.424 1.00 56.01  ? 365 ALA A O   1 
ATOM   2656  C  CB  . ALA A 1 365 ? 152.757 145.309 167.613 1.00 56.01  ? 365 ALA A CB  1 
ATOM   2657  N  N   . VAL A 1 366 ? 152.715 147.385 170.392 1.00 51.85  ? 366 VAL A N   1 
ATOM   2658  C  CA  . VAL A 1 366 ? 152.485 147.462 171.829 1.00 51.85  ? 366 VAL A CA  1 
ATOM   2659  C  C   . VAL A 1 366 ? 151.081 146.955 172.119 1.00 51.85  ? 366 VAL A C   1 
ATOM   2660  O  O   . VAL A 1 366 ? 150.099 147.526 171.632 1.00 51.85  ? 366 VAL A O   1 
ATOM   2661  C  CB  . VAL A 1 366 ? 152.656 148.898 172.355 1.00 51.85  ? 366 VAL A CB  1 
ATOM   2662  C  CG1 . VAL A 1 366 ? 152.339 148.957 173.840 1.00 51.85  ? 366 VAL A CG1 1 
ATOM   2663  C  CG2 . VAL A 1 366 ? 154.057 149.406 172.073 1.00 51.85  ? 366 VAL A CG2 1 
ATOM   2664  N  N   . ILE A 1 367 ? 150.985 145.887 172.911 1.00 54.73  ? 367 ILE A N   1 
ATOM   2665  C  CA  . ILE A 1 367 ? 149.695 145.372 173.348 1.00 54.73  ? 367 ILE A CA  1 
ATOM   2666  C  C   . ILE A 1 367 ? 149.594 145.580 174.851 1.00 54.73  ? 367 ILE A C   1 
ATOM   2667  O  O   . ILE A 1 367 ? 150.533 146.049 175.497 1.00 54.73  ? 367 ILE A O   1 
ATOM   2668  C  CB  . ILE A 1 367 ? 149.496 143.886 172.988 1.00 54.73  ? 367 ILE A CB  1 
ATOM   2669  C  CG1 . ILE A 1 367 ? 150.541 143.023 173.688 1.00 54.73  ? 367 ILE A CG1 1 
ATOM   2670  C  CG2 . ILE A 1 367 ? 149.569 143.688 171.484 1.00 54.73  ? 367 ILE A CG2 1 
ATOM   2671  C  CD1 . ILE A 1 367 ? 150.303 141.544 173.533 1.00 54.73  ? 367 ILE A CD1 1 
ATOM   2672  N  N   . TYR A 1 368 ? 148.435 145.238 175.413 1.00 60.58  ? 368 TYR A N   1 
ATOM   2673  C  CA  . TYR A 1 368 ? 148.265 145.367 176.852 1.00 60.58  ? 368 TYR A CA  1 
ATOM   2674  C  C   . TYR A 1 368 ? 147.171 144.448 177.371 1.00 60.58  ? 368 TYR A C   1 
ATOM   2675  O  O   . TYR A 1 368 ? 146.312 143.974 176.622 1.00 60.58  ? 368 TYR A O   1 
ATOM   2676  C  CB  . TYR A 1 368 ? 147.971 146.813 177.269 1.00 60.58  ? 368 TYR A CB  1 
ATOM   2677  C  CG  . TYR A 1 368 ? 146.679 147.418 176.784 1.00 60.58  ? 368 TYR A CG  1 
ATOM   2678  C  CD1 . TYR A 1 368 ? 146.615 148.077 175.567 1.00 60.58  ? 368 TYR A CD1 1 
ATOM   2679  C  CD2 . TYR A 1 368 ? 145.536 147.383 177.571 1.00 60.58  ? 368 TYR A CD2 1 
ATOM   2680  C  CE1 . TYR A 1 368 ? 145.441 148.654 175.129 1.00 60.58  ? 368 TYR A CE1 1 
ATOM   2681  C  CE2 . TYR A 1 368 ? 144.357 147.957 177.142 1.00 60.58  ? 368 TYR A CE2 1 
ATOM   2682  C  CZ  . TYR A 1 368 ? 144.317 148.594 175.921 1.00 60.58  ? 368 TYR A CZ  1 
ATOM   2683  O  OH  . TYR A 1 368 ? 143.146 149.166 175.482 1.00 60.58  ? 368 TYR A OH  1 
ATOM   2684  N  N   . TYR A 1 369 ? 147.223 144.222 178.683 1.00 63.63  ? 369 TYR A N   1 
ATOM   2685  C  CA  . TYR A 1 369 ? 146.389 143.266 179.402 1.00 63.63  ? 369 TYR A CA  1 
ATOM   2686  C  C   . TYR A 1 369 ? 145.805 143.974 180.614 1.00 63.63  ? 369 TYR A C   1 
ATOM   2687  O  O   . TYR A 1 369 ? 146.551 144.445 181.480 1.00 63.63  ? 369 TYR A O   1 
ATOM   2688  C  CB  . TYR A 1 369 ? 147.215 142.051 179.823 1.00 63.63  ? 369 TYR A CB  1 
ATOM   2689  C  CG  . TYR A 1 369 ? 146.480 141.016 180.644 1.00 63.63  ? 369 TYR A CG  1 
ATOM   2690  C  CD1 . TYR A 1 369 ? 145.609 140.117 180.050 1.00 63.63  ? 369 TYR A CD1 1 
ATOM   2691  C  CD2 . TYR A 1 369 ? 146.676 140.926 182.016 1.00 63.63  ? 369 TYR A CD2 1 
ATOM   2692  C  CE1 . TYR A 1 369 ? 144.946 139.165 180.799 1.00 63.63  ? 369 TYR A CE1 1 
ATOM   2693  C  CE2 . TYR A 1 369 ? 146.018 139.979 182.772 1.00 63.63  ? 369 TYR A CE2 1 
ATOM   2694  C  CZ  . TYR A 1 369 ? 145.153 139.102 182.159 1.00 63.63  ? 369 TYR A CZ  1 
ATOM   2695  O  OH  . TYR A 1 369 ? 144.493 138.155 182.908 1.00 63.63  ? 369 TYR A OH  1 
ATOM   2696  N  N   . ARG A 1 370 ? 144.479 144.056 180.672 1.00 67.19  ? 370 ARG A N   1 
ATOM   2697  C  CA  . ARG A 1 370 ? 143.787 144.670 181.797 1.00 67.19  ? 370 ARG A CA  1 
ATOM   2698  C  C   . ARG A 1 370 ? 143.432 143.595 182.814 1.00 67.19  ? 370 ARG A C   1 
ATOM   2699  O  O   . ARG A 1 370 ? 142.667 142.674 182.509 1.00 67.19  ? 370 ARG A O   1 
ATOM   2700  C  CB  . ARG A 1 370 ? 142.527 145.399 181.334 1.00 67.19  ? 370 ARG A CB  1 
ATOM   2701  C  CG  . ARG A 1 370 ? 142.782 146.659 180.530 1.00 67.19  ? 370 ARG A CG  1 
ATOM   2702  C  CD  . ARG A 1 370 ? 141.470 147.320 180.142 1.00 67.19  ? 370 ARG A CD  1 
ATOM   2703  N  NE  . ARG A 1 370 ? 141.677 148.508 179.320 1.00 67.19  ? 370 ARG A NE  1 
ATOM   2704  C  CZ  . ARG A 1 370 ? 141.833 149.733 179.810 1.00 67.19  ? 370 ARG A CZ  1 
ATOM   2705  N  NH1 . ARG A 1 370 ? 141.800 149.933 181.120 1.00 67.19  ? 370 ARG A NH1 1 
ATOM   2706  N  NH2 . ARG A 1 370 ? 142.017 150.759 178.990 1.00 67.19  ? 370 ARG A NH2 1 
ATOM   2707  N  N   . VAL A 1 371 ? 143.988 143.711 184.020 1.00 66.31  ? 371 VAL A N   1 
ATOM   2708  C  CA  . VAL A 1 371 ? 143.651 142.768 185.082 1.00 66.31  ? 371 VAL A CA  1 
ATOM   2709  C  C   . VAL A 1 371 ? 142.208 142.970 185.524 1.00 66.31  ? 371 VAL A C   1 
ATOM   2710  O  O   . VAL A 1 371 ? 141.776 144.095 185.804 1.00 66.31  ? 371 VAL A O   1 
ATOM   2711  C  CB  . VAL A 1 371 ? 144.631 142.911 186.259 1.00 66.31  ? 371 VAL A CB  1 
ATOM   2712  C  CG1 . VAL A 1 371 ? 144.224 141.994 187.400 1.00 66.31  ? 371 VAL A CG1 1 
ATOM   2713  C  CG2 . VAL A 1 371 ? 146.046 142.605 185.801 1.00 66.31  ? 371 VAL A CG2 1 
ATOM   2714  N  N   . GLY A 1 372 ? 141.438 141.884 185.590 1.00 72.09  ? 372 GLY A N   1 
ATOM   2715  C  CA  . GLY A 1 372 ? 140.017 142.018 185.860 1.00 72.09  ? 372 GLY A CA  1 
ATOM   2716  C  C   . GLY A 1 372 ? 139.178 141.856 184.607 1.00 72.09  ? 372 GLY A C   1 
ATOM   2717  O  O   . GLY A 1 372 ? 138.378 140.923 184.502 1.00 72.09  ? 372 GLY A O   1 
ATOM   2718  N  N   . ASP A 1 373 ? 139.346 142.763 183.641 1.00 72.08  ? 373 ASP A N   1 
ATOM   2719  C  CA  . ASP A 1 373 ? 138.720 142.578 182.339 1.00 72.08  ? 373 ASP A CA  1 
ATOM   2720  C  C   . ASP A 1 373 ? 139.286 141.362 181.619 1.00 72.08  ? 373 ASP A C   1 
ATOM   2721  O  O   . ASP A 1 373 ? 138.555 140.685 180.887 1.00 72.08  ? 373 ASP A O   1 
ATOM   2722  C  CB  . ASP A 1 373 ? 138.900 143.831 181.481 1.00 72.08  ? 373 ASP A CB  1 
ATOM   2723  C  CG  . ASP A 1 373 ? 138.122 145.019 182.012 1.00 72.08  ? 373 ASP A CG  1 
ATOM   2724  O  OD1 . ASP A 1 373 ? 137.072 144.806 182.654 1.00 72.08  ? 373 ASP A OD1 1 
ATOM   2725  O  OD2 . ASP A 1 373 ? 138.560 146.166 181.786 1.00 72.08  ? 373 ASP A OD2 1 
ATOM   2726  N  N   . ASN A 1 374 ? 140.577 141.083 181.813 1.00 71.58  ? 374 ASN A N   1 
ATOM   2727  C  CA  . ASN A 1 374 ? 141.209 139.848 181.347 1.00 71.58  ? 374 ASN A CA  1 
ATOM   2728  C  C   . ASN A 1 374 ? 141.126 139.720 179.826 1.00 71.58  ? 374 ASN A C   1 
ATOM   2729  O  O   . ASN A 1 374 ? 140.884 138.640 179.285 1.00 71.58  ? 374 ASN A O   1 
ATOM   2730  C  CB  . ASN A 1 374 ? 140.591 138.630 182.042 1.00 71.58  ? 374 ASN A CB  1 
ATOM   2731  C  CG  . ASN A 1 374 ? 141.419 137.374 181.876 1.00 71.58  ? 374 ASN A CG  1 
ATOM   2732  O  OD1 . ASN A 1 374 ? 142.457 137.380 181.218 1.00 71.58  ? 374 ASN A OD1 1 
ATOM   2733  N  ND2 . ASN A 1 374 ? 140.964 136.285 182.484 1.00 71.58  ? 374 ASN A ND2 1 
ATOM   2734  N  N   . VAL A 1 375 ? 141.323 140.837 179.128 1.00 70.45  ? 375 VAL A N   1 
ATOM   2735  C  CA  . VAL A 1 375 ? 141.264 140.878 177.671 1.00 70.45  ? 375 VAL A CA  1 
ATOM   2736  C  C   . VAL A 1 375 ? 142.399 141.755 177.160 1.00 70.45  ? 375 VAL A C   1 
ATOM   2737  O  O   . VAL A 1 375 ? 142.447 142.953 177.458 1.00 70.45  ? 375 VAL A O   1 
ATOM   2738  C  CB  . VAL A 1 375 ? 139.907 141.406 177.163 1.00 70.45  ? 375 VAL A CB  1 
ATOM   2739  C  CG1 . VAL A 1 375 ? 139.937 141.567 175.654 1.00 70.45  ? 375 VAL A CG1 1 
ATOM   2740  C  CG2 . VAL A 1 375 ? 138.775 140.472 177.569 1.00 70.45  ? 375 VAL A CG2 1 
ATOM   2741  N  N   . TRP A 1 376 ? 143.307 141.157 176.390 1.00 67.29  ? 376 TRP A N   1 
ATOM   2742  C  CA  . TRP A 1 376 ? 144.391 141.881 175.726 1.00 67.29  ? 376 TRP A CA  1 
ATOM   2743  C  C   . TRP A 1 376 ? 143.769 142.815 174.699 1.00 67.29  ? 376 TRP A C   1 
ATOM   2744  O  O   . TRP A 1 376 ? 142.651 142.586 174.235 1.00 67.29  ? 376 TRP A O   1 
ATOM   2745  C  CB  . TRP A 1 376 ? 145.359 140.903 175.074 1.00 67.29  ? 376 TRP A CB  1 
ATOM   2746  C  CG  . TRP A 1 376 ? 146.141 140.095 176.051 1.00 67.29  ? 376 TRP A CG  1 
ATOM   2747  C  CD1 . TRP A 1 376 ? 145.790 138.891 176.582 1.00 67.29  ? 376 TRP A CD1 1 
ATOM   2748  C  CD2 . TRP A 1 376 ? 147.429 140.411 176.589 1.00 67.29  ? 376 TRP A CD2 1 
ATOM   2749  N  NE1 . TRP A 1 376 ? 146.768 138.448 177.437 1.00 67.29  ? 376 TRP A NE1 1 
ATOM   2750  C  CE2 . TRP A 1 376 ? 147.788 139.362 177.455 1.00 67.29  ? 376 TRP A CE2 1 
ATOM   2751  C  CE3 . TRP A 1 376 ? 148.311 141.483 176.428 1.00 67.29  ? 376 TRP A CE3 1 
ATOM   2752  C  CZ2 . TRP A 1 376 ? 148.987 139.355 178.158 1.00 67.29  ? 376 TRP A CZ2 1 
ATOM   2753  C  CZ3 . TRP A 1 376 ? 149.501 141.473 177.126 1.00 67.29  ? 376 TRP A CZ3 1 
ATOM   2754  C  CH2 . TRP A 1 376 ? 149.828 140.417 177.981 1.00 67.29  ? 376 TRP A CH2 1 
ATOM   2755  N  N   . THR A 1 377 ? 144.487 143.872 174.330 1.00 60.60  ? 377 THR A N   1 
ATOM   2756  C  CA  . THR A 1 377 ? 143.950 144.803 173.349 1.00 60.60  ? 377 THR A CA  1 
ATOM   2757  C  C   . THR A 1 377 ? 145.059 145.199 172.368 1.00 60.60  ? 377 THR A C   1 
ATOM   2758  O  O   . THR A 1 377 ? 145.716 144.344 171.768 1.00 60.60  ? 377 THR A O   1 
ATOM   2759  C  CB  . THR A 1 377 ? 143.312 145.995 174.064 1.00 60.60  ? 377 THR A CB  1 
ATOM   2760  O  OG1 . THR A 1 377 ? 142.470 145.515 175.119 1.00 60.60  ? 377 THR A OG1 1 
ATOM   2761  C  CG2 . THR A 1 377 ? 142.422 146.793 173.109 1.00 60.60  ? 377 THR A CG2 1 
ATOM   2762  N  N   . GLU A 1 378 ? 145.291 146.501 172.205 1.00 60.89  ? 378 GLU A N   1 
ATOM   2763  C  CA  . GLU A 1 378 ? 146.192 147.036 171.197 1.00 60.89  ? 378 GLU A CA  1 
ATOM   2764  C  C   . GLU A 1 378 ? 146.323 148.543 171.376 1.00 60.89  ? 378 GLU A C   1 
ATOM   2765  O  O   . GLU A 1 378 ? 145.378 149.225 171.782 1.00 60.89  ? 378 GLU A O   1 
ATOM   2766  C  CB  . GLU A 1 378 ? 145.688 146.719 169.780 1.00 60.89  ? 378 GLU A CB  1 
ATOM   2767  C  CG  . GLU A 1 378 ? 146.599 147.176 168.652 1.00 60.89  ? 378 GLU A CG  1 
ATOM   2768  C  CD  . GLU A 1 378 ? 147.909 146.417 168.611 1.00 60.89  ? 378 GLU A CD  1 
ATOM   2769  O  OE1 . GLU A 1 378 ? 147.946 145.263 169.088 1.00 60.89  ? 378 GLU A OE1 1 
ATOM   2770  O  OE2 . GLU A 1 378 ? 148.901 146.972 168.092 1.00 60.89  ? 378 GLU A OE2 1 
ATOM   2771  N  N   . THR A 1 379 ? 147.512 149.061 171.071 1.00 55.77  ? 379 THR A N   1 
ATOM   2772  C  CA  . THR A 1 379 ? 147.791 150.487 171.164 1.00 55.77  ? 379 THR A CA  1 
ATOM   2773  C  C   . THR A 1 379 ? 148.646 150.865 169.957 1.00 55.77  ? 379 THR A C   1 
ATOM   2774  O  O   . THR A 1 379 ? 148.927 150.032 169.090 1.00 55.77  ? 379 THR A O   1 
ATOM   2775  C  CB  . THR A 1 379 ? 148.464 150.814 172.506 1.00 55.77  ? 379 THR A CB  1 
ATOM   2776  O  OG1 . THR A 1 379 ? 147.754 150.151 173.557 1.00 55.77  ? 379 THR A OG1 1 
ATOM   2777  C  CG2 . THR A 1 379 ? 148.399 152.306 172.808 1.00 55.77  ? 379 THR A CG2 1 
ATOM   2778  N  N   . THR A 1 380 ? 149.056 152.130 169.888 1.00 55.68  ? 380 THR A N   1 
ATOM   2779  C  CA  . THR A 1 380 ? 149.865 152.605 168.777 1.00 55.68  ? 380 THR A CA  1 
ATOM   2780  C  C   . THR A 1 380 ? 151.195 151.859 168.712 1.00 55.68  ? 380 THR A C   1 
ATOM   2781  O  O   . THR A 1 380 ? 151.599 151.159 169.644 1.00 55.68  ? 380 THR A O   1 
ATOM   2782  C  CB  . THR A 1 380 ? 150.120 154.107 168.899 1.00 55.68  ? 380 THR A CB  1 
ATOM   2783  O  OG1 . THR A 1 380 ? 150.767 154.581 167.711 1.00 55.68  ? 380 THR A OG1 1 
ATOM   2784  C  CG2 . THR A 1 380 ? 151.006 154.397 170.095 1.00 55.68  ? 380 THR A CG2 1 
ATOM   2785  N  N   . GLN A 1 381 ? 151.881 152.022 167.585 1.00 59.18  ? 381 GLN A N   1 
ATOM   2786  C  CA  . GLN A 1 381 ? 153.123 151.309 167.348 1.00 59.18  ? 381 GLN A CA  1 
ATOM   2787  C  C   . GLN A 1 381 ? 154.324 152.140 167.790 1.00 59.18  ? 381 GLN A C   1 
ATOM   2788  O  O   . GLN A 1 381 ? 154.242 153.356 167.978 1.00 59.18  ? 381 GLN A O   1 
ATOM   2789  C  CB  . GLN A 1 381 ? 153.258 150.946 165.869 1.00 59.18  ? 381 GLN A CB  1 
ATOM   2790  C  CG  . GLN A 1 381 ? 152.247 149.919 165.391 1.00 59.18  ? 381 GLN A CG  1 
ATOM   2791  C  CD  . GLN A 1 381 ? 152.418 149.575 163.926 1.00 59.18  ? 381 GLN A CD  1 
ATOM   2792  O  OE1 . GLN A 1 381 ? 153.253 150.155 163.233 1.00 59.18  ? 381 GLN A OE1 1 
ATOM   2793  N  NE2 . GLN A 1 381 ? 151.626 148.623 163.446 1.00 59.18  ? 381 GLN A NE2 1 
ATOM   2794  N  N   . LEU A 1 382 ? 155.452 151.457 167.956 1.00 55.51  ? 382 LEU A N   1 
ATOM   2795  C  CA  . LEU A 1 382 ? 156.693 152.128 168.307 1.00 55.51  ? 382 LEU A CA  1 
ATOM   2796  C  C   . LEU A 1 382 ? 157.238 152.891 167.104 1.00 55.51  ? 382 LEU A C   1 
ATOM   2797  O  O   . LEU A 1 382 ? 156.925 152.583 165.952 1.00 55.51  ? 382 LEU A O   1 
ATOM   2798  C  CB  . LEU A 1 382 ? 157.727 151.113 168.794 1.00 55.51  ? 382 LEU A CB  1 
ATOM   2799  C  CG  . LEU A 1 382 ? 157.388 150.307 170.051 1.00 55.51  ? 382 LEU A CG  1 
ATOM   2800  C  CD1 . LEU A 1 382 ? 158.456 149.262 170.317 1.00 55.51  ? 382 LEU A CD1 1 
ATOM   2801  C  CD2 . LEU A 1 382 ? 157.211 151.209 171.259 1.00 55.51  ? 382 LEU A CD2 1 
ATOM   2802  N  N   . GLU A 1 383 ? 158.061 153.905 167.383 1.00 58.59  ? 383 GLU A N   1 
ATOM   2803  C  CA  . GLU A 1 383 ? 158.691 154.654 166.301 1.00 58.59  ? 383 GLU A CA  1 
ATOM   2804  C  C   . GLU A 1 383 ? 159.649 153.775 165.509 1.00 58.59  ? 383 GLU A C   1 
ATOM   2805  O  O   . GLU A 1 383 ? 159.455 153.558 164.307 1.00 58.59  ? 383 GLU A O   1 
ATOM   2806  C  CB  . GLU A 1 383 ? 159.417 155.878 166.856 1.00 58.59  ? 383 GLU A CB  1 
ATOM   2807  C  CG  . GLU A 1 383 ? 158.489 156.964 167.368 1.00 58.59  ? 383 GLU A CG  1 
ATOM   2808  C  CD  . GLU A 1 383 ? 157.707 157.638 166.254 1.00 58.59  ? 383 GLU A CD  1 
ATOM   2809  O  OE1 . GLU A 1 383 ? 158.248 157.757 165.134 1.00 58.59  ? 383 GLU A OE1 1 
ATOM   2810  O  OE2 . GLU A 1 383 ? 156.553 158.048 166.496 1.00 58.59  ? 383 GLU A OE2 1 
ATOM   2811  N  N   . VAL A 1 384 ? 160.689 153.260 166.161 1.00 53.82  ? 384 VAL A N   1 
ATOM   2812  C  CA  . VAL A 1 384 ? 161.602 152.312 165.537 1.00 53.82  ? 384 VAL A CA  1 
ATOM   2813  C  C   . VAL A 1 384 ? 161.520 150.996 166.298 1.00 53.82  ? 384 VAL A C   1 
ATOM   2814  O  O   . VAL A 1 384 ? 161.440 150.970 167.530 1.00 53.82  ? 384 VAL A O   1 
ATOM   2815  C  CB  . VAL A 1 384 ? 163.053 152.851 165.479 1.00 53.82  ? 384 VAL A CB  1 
ATOM   2816  C  CG1 . VAL A 1 384 ? 163.632 153.036 166.869 1.00 53.82  ? 384 VAL A CG1 1 
ATOM   2817  C  CG2 . VAL A 1 384 ? 163.931 151.929 164.650 1.00 53.82  ? 384 VAL A CG2 1 
ATOM   2818  N  N   . ALA A 1 385 ? 161.507 149.897 165.549 1.00 56.10  ? 385 ALA A N   1 
ATOM   2819  C  CA  . ALA A 1 385 ? 161.371 148.579 166.151 1.00 56.10  ? 385 ALA A CA  1 
ATOM   2820  C  C   . ALA A 1 385 ? 162.623 148.214 166.935 1.00 56.10  ? 385 ALA A C   1 
ATOM   2821  O  O   . ALA A 1 385 ? 163.736 148.613 166.583 1.00 56.10  ? 385 ALA A O   1 
ATOM   2822  C  CB  . ALA A 1 385 ? 161.102 147.530 165.074 1.00 56.10  ? 385 ALA A CB  1 
ATOM   2823  N  N   . VAL A 1 386 ? 162.435 147.443 168.006 1.00 52.73  ? 386 VAL A N   1 
ATOM   2824  C  CA  . VAL A 1 386 ? 163.538 147.045 168.870 1.00 52.73  ? 386 VAL A CA  1 
ATOM   2825  C  C   . VAL A 1 386 ? 163.098 145.818 169.653 1.00 52.73  ? 386 VAL A C   1 
ATOM   2826  O  O   . VAL A 1 386 ? 161.924 145.676 170.004 1.00 52.73  ? 386 VAL A O   1 
ATOM   2827  C  CB  . VAL A 1 386 ? 163.965 148.209 169.800 1.00 52.73  ? 386 VAL A CB  1 
ATOM   2828  C  CG1 . VAL A 1 386 ? 162.857 148.555 170.776 1.00 52.73  ? 386 VAL A CG1 1 
ATOM   2829  C  CG2 . VAL A 1 386 ? 165.244 147.869 170.535 1.00 52.73  ? 386 VAL A CG2 1 
ATOM   2830  N  N   . SER A 1 387 ? 164.044 144.917 169.909 1.00 51.74  ? 387 SER A N   1 
ATOM   2831  C  CA  . SER A 1 387 ? 163.775 143.701 170.660 1.00 51.74  ? 387 SER A CA  1 
ATOM   2832  C  C   . SER A 1 387 ? 164.744 143.605 171.826 1.00 51.74  ? 387 SER A C   1 
ATOM   2833  O  O   . SER A 1 387 ? 165.801 144.240 171.829 1.00 51.74  ? 387 SER A O   1 
ATOM   2834  C  CB  . SER A 1 387 ? 163.904 142.450 169.789 1.00 51.74  ? 387 SER A CB  1 
ATOM   2835  O  OG  . SER A 1 387 ? 165.252 142.236 169.408 1.00 51.74  ? 387 SER A OG  1 
ATOM   2836  N  N   . GLY A 1 388 ? 164.376 142.791 172.813 1.00 46.24  ? 388 GLY A N   1 
ATOM   2837  C  CA  . GLY A 1 388 ? 165.208 142.590 173.981 1.00 46.24  ? 388 GLY A CA  1 
ATOM   2838  C  C   . GLY A 1 388 ? 165.546 143.841 174.753 1.00 46.24  ? 388 GLY A C   1 
ATOM   2839  O  O   . GLY A 1 388 ? 166.606 143.895 175.381 1.00 46.24  ? 388 GLY A O   1 
ATOM   2840  N  N   . ALA A 1 389 ? 164.685 144.854 174.722 1.00 41.10  ? 389 ALA A N   1 
ATOM   2841  C  CA  . ALA A 1 389 ? 164.967 146.090 175.428 1.00 41.10  ? 389 ALA A CA  1 
ATOM   2842  C  C   . ALA A 1 389 ? 164.644 145.938 176.912 1.00 41.10  ? 389 ALA A C   1 
ATOM   2843  O  O   . ALA A 1 389 ? 164.175 144.894 177.375 1.00 41.10  ? 389 ALA A O   1 
ATOM   2844  C  CB  . ALA A 1 389 ? 164.177 147.245 174.819 1.00 41.10  ? 389 ALA A CB  1 
ATOM   2845  N  N   . ALA A 1 390 ? 164.907 147.000 177.665 1.00 33.03  ? 390 ALA A N   1 
ATOM   2846  C  CA  . ALA A 1 390 ? 164.672 147.031 179.101 1.00 33.03  ? 390 ALA A CA  1 
ATOM   2847  C  C   . ALA A 1 390 ? 163.702 148.160 179.411 1.00 33.03  ? 390 ALA A C   1 
ATOM   2848  O  O   . ALA A 1 390 ? 164.094 149.331 179.422 1.00 33.03  ? 390 ALA A O   1 
ATOM   2849  C  CB  . ALA A 1 390 ? 165.980 147.218 179.868 1.00 33.03  ? 390 ALA A CB  1 
ATOM   2850  N  N   . GLY A 1 391 ? 162.444 147.809 179.654 1.00 31.28  ? 391 GLY A N   1 
ATOM   2851  C  CA  . GLY A 1 391 ? 161.427 148.798 179.937 1.00 31.28  ? 391 GLY A CA  1 
ATOM   2852  C  C   . GLY A 1 391 ? 161.344 149.134 181.414 1.00 31.28  ? 391 GLY A C   1 
ATOM   2853  O  O   . GLY A 1 391 ? 161.576 148.293 182.277 1.00 31.28  ? 391 GLY A O   1 
ATOM   2854  N  N   . ALA A 1 392 ? 161.006 150.390 181.697 1.00 31.40  ? 392 ALA A N   1 
ATOM   2855  C  CA  . ALA A 1 392 ? 160.861 150.843 183.078 1.00 31.40  ? 392 ALA A CA  1 
ATOM   2856  C  C   . ALA A 1 392 ? 159.913 152.034 183.084 1.00 31.40  ? 392 ALA A C   1 
ATOM   2857  O  O   . ALA A 1 392 ? 160.172 153.027 182.397 1.00 31.40  ? 392 ALA A O   1 
ATOM   2858  C  CB  . ALA A 1 392 ? 162.213 151.210 183.672 1.00 31.40  ? 392 ALA A CB  1 
ATOM   2859  N  N   . ASN A 1 393 ? 158.830 151.940 183.853 1.00 37.66  ? 393 ASN A N   1 
ATOM   2860  C  CA  . ASN A 1 393 ? 157.809 152.980 183.872 1.00 37.66  ? 393 ASN A CA  1 
ATOM   2861  C  C   . ASN A 1 393 ? 158.019 153.944 185.034 1.00 37.66  ? 393 ASN A C   1 
ATOM   2862  O  O   . ASN A 1 393 ? 158.343 153.529 186.150 1.00 37.66  ? 393 ASN A O   1 
ATOM   2863  C  CB  . ASN A 1 393 ? 156.407 152.367 183.937 1.00 37.66  ? 393 ASN A CB  1 
ATOM   2864  C  CG  . ASN A 1 393 ? 156.212 151.440 185.126 1.00 37.66  ? 393 ASN A CG  1 
ATOM   2865  O  OD1 . ASN A 1 393 ? 157.117 151.229 185.929 1.00 37.66  ? 393 ASN A OD1 1 
ATOM   2866  N  ND2 . ASN A 1 393 ? 155.010 150.893 185.248 1.00 37.66  ? 393 ASN A ND2 1 
ATOM   2867  N  N   . LEU A 1 394 ? 157.835 155.231 184.764 1.00 40.66  ? 394 LEU A N   1 
ATOM   2868  C  CA  . LEU A 1 394 ? 157.899 156.283 185.775 1.00 40.66  ? 394 LEU A CA  1 
ATOM   2869  C  C   . LEU A 1 394 ? 156.510 156.903 185.885 1.00 40.66  ? 394 LEU A C   1 
ATOM   2870  O  O   . LEU A 1 394 ? 156.100 157.679 185.021 1.00 40.66  ? 394 LEU A O   1 
ATOM   2871  C  CB  . LEU A 1 394 ? 158.948 157.321 185.419 1.00 40.66  ? 394 LEU A CB  1 
ATOM   2872  C  CG  . LEU A 1 394 ? 160.391 156.859 185.572 1.00 40.66  ? 394 LEU A CG  1 
ATOM   2873  C  CD1 . LEU A 1 394 ? 161.321 157.871 184.972 1.00 40.66  ? 394 LEU A CD1 1 
ATOM   2874  C  CD2 . LEU A 1 394 ? 160.701 156.692 187.036 1.00 40.66  ? 394 LEU A CD2 1 
ATOM   2875  N  N   . ASN A 1 395 ? 155.815 156.563 186.971 1.00 44.81  ? 395 ASN A N   1 
ATOM   2876  C  CA  . ASN A 1 395 ? 154.426 156.942 187.263 1.00 44.81  ? 395 ASN A CA  1 
ATOM   2877  C  C   . ASN A 1 395 ? 153.660 157.375 186.010 1.00 44.81  ? 395 ASN A C   1 
ATOM   2878  O  O   . ASN A 1 395 ? 153.144 158.487 185.902 1.00 44.81  ? 395 ASN A O   1 
ATOM   2879  C  CB  . ASN A 1 395 ? 154.368 158.010 188.362 1.00 44.81  ? 395 ASN A CB  1 
ATOM   2880  C  CG  . ASN A 1 395 ? 155.090 159.300 187.996 1.00 44.81  ? 395 ASN A CG  1 
ATOM   2881  O  OD1 . ASN A 1 395 ? 155.531 159.493 186.867 1.00 44.81  ? 395 ASN A OD1 1 
ATOM   2882  N  ND2 . ASN A 1 395 ? 155.211 160.194 188.970 1.00 44.81  ? 395 ASN A ND2 1 
ATOM   2883  N  N   . GLY A 1 396 ? 153.598 156.453 185.052 1.00 40.82  ? 396 GLY A N   1 
ATOM   2884  C  CA  . GLY A 1 396 ? 152.907 156.701 183.804 1.00 40.82  ? 396 GLY A CA  1 
ATOM   2885  C  C   . GLY A 1 396 ? 153.719 156.336 182.579 1.00 40.82  ? 396 GLY A C   1 
ATOM   2886  O  O   . GLY A 1 396 ? 153.542 155.258 182.007 1.00 40.82  ? 396 GLY A O   1 
ATOM   2887  N  N   . ILE A 1 397 ? 154.622 157.231 182.173 1.00 38.97  ? 397 ILE A N   1 
ATOM   2888  C  CA  . ILE A 1 397 ? 155.383 157.033 180.946 1.00 38.97  ? 397 ILE A CA  1 
ATOM   2889  C  C   . ILE A 1 397 ? 156.271 155.809 181.085 1.00 38.97  ? 397 ILE A C   1 
ATOM   2890  O  O   . ILE A 1 397 ? 156.958 155.633 182.096 1.00 38.97  ? 397 ILE A O   1 
ATOM   2891  C  CB  . ILE A 1 397 ? 156.208 158.290 180.620 1.00 38.97  ? 397 ILE A CB  1 
ATOM   2892  C  CG1 . ILE A 1 397 ? 155.295 159.483 180.330 1.00 38.97  ? 397 ILE A CG1 1 
ATOM   2893  C  CG2 . ILE A 1 397 ? 157.124 158.036 179.443 1.00 38.97  ? 397 ILE A CG2 1 
ATOM   2894  C  CD1 . ILE A 1 397 ? 154.981 160.335 181.541 1.00 38.97  ? 397 ILE A CD1 1 
ATOM   2895  N  N   . ILE A 1 398 ? 156.259 154.955 180.066 1.00 37.89  ? 398 ILE A N   1 
ATOM   2896  C  CA  . ILE A 1 398 ? 157.100 153.765 180.019 1.00 37.89  ? 398 ILE A CA  1 
ATOM   2897  C  C   . ILE A 1 398 ? 158.308 154.056 179.144 1.00 37.89  ? 398 ILE A C   1 
ATOM   2898  O  O   . ILE A 1 398 ? 158.162 154.404 177.966 1.00 37.89  ? 398 ILE A O   1 
ATOM   2899  C  CB  . ILE A 1 398 ? 156.324 152.550 179.490 1.00 37.89  ? 398 ILE A CB  1 
ATOM   2900  C  CG1 . ILE A 1 398 ? 155.236 152.141 180.479 1.00 37.89  ? 398 ILE A CG1 1 
ATOM   2901  C  CG2 . ILE A 1 398 ? 157.267 151.398 179.207 1.00 37.89  ? 398 ILE A CG2 1 
ATOM   2902  C  CD1 . ILE A 1 398 ? 154.314 151.095 179.942 1.00 37.89  ? 398 ILE A CD1 1 
ATOM   2903  N  N   . TYR A 1 399 ? 159.498 153.911 179.715 1.00 33.30  ? 399 TYR A N   1 
ATOM   2904  C  CA  . TYR A 1 399 ? 160.743 154.138 178.999 1.00 33.30  ? 399 TYR A CA  1 
ATOM   2905  C  C   . TYR A 1 399 ? 161.318 152.815 178.519 1.00 33.30  ? 399 TYR A C   1 
ATOM   2906  O  O   . TYR A 1 399 ? 161.630 151.930 179.321 1.00 33.30  ? 399 TYR A O   1 
ATOM   2907  C  CB  . TYR A 1 399 ? 161.756 154.867 179.882 1.00 33.30  ? 399 TYR A CB  1 
ATOM   2908  C  CG  . TYR A 1 399 ? 161.377 156.302 180.151 1.00 33.30  ? 399 TYR A CG  1 
ATOM   2909  C  CD1 . TYR A 1 399 ? 161.674 157.297 179.234 1.00 33.30  ? 399 TYR A CD1 1 
ATOM   2910  C  CD2 . TYR A 1 399 ? 160.698 156.658 181.306 1.00 33.30  ? 399 TYR A CD2 1 
ATOM   2911  C  CE1 . TYR A 1 399 ? 161.324 158.607 179.466 1.00 33.30  ? 399 TYR A CE1 1 
ATOM   2912  C  CE2 . TYR A 1 399 ? 160.342 157.969 181.546 1.00 33.30  ? 399 TYR A CE2 1 
ATOM   2913  C  CZ  . TYR A 1 399 ? 160.658 158.938 180.621 1.00 33.30  ? 399 TYR A CZ  1 
ATOM   2914  O  OH  . TYR A 1 399 ? 160.310 160.248 180.847 1.00 33.30  ? 399 TYR A OH  1 
ATOM   2915  N  N   . LEU A 1 400 ? 161.450 152.687 177.202 1.00 33.02  ? 400 LEU A N   1 
ATOM   2916  C  CA  . LEU A 1 400 ? 161.954 151.464 176.595 1.00 33.02  ? 400 LEU A CA  1 
ATOM   2917  C  C   . LEU A 1 400 ? 163.431 151.640 176.271 1.00 33.02  ? 400 LEU A C   1 
ATOM   2918  O  O   . LEU A 1 400 ? 163.784 152.281 175.278 1.00 33.02  ? 400 LEU A O   1 
ATOM   2919  C  CB  . LEU A 1 400 ? 161.146 151.127 175.343 1.00 33.02  ? 400 LEU A CB  1 
ATOM   2920  C  CG  . LEU A 1 400 ? 161.380 149.760 174.713 1.00 33.02  ? 400 LEU A CG  1 
ATOM   2921  C  CD1 . LEU A 1 400 ? 160.959 148.677 175.684 1.00 33.02  ? 400 LEU A CD1 1 
ATOM   2922  C  CD2 . LEU A 1 400 ? 160.603 149.647 173.419 1.00 33.02  ? 400 LEU A CD2 1 
ATOM   2923  N  N   . LEU A 1 401 ? 164.298 151.071 177.104 1.00 33.28  ? 401 LEU A N   1 
ATOM   2924  C  CA  . LEU A 1 401 ? 165.714 151.409 177.061 1.00 33.28  ? 401 LEU A CA  1 
ATOM   2925  C  C   . LEU A 1 401 ? 166.503 150.388 176.253 1.00 33.28  ? 401 LEU A C   1 
ATOM   2926  O  O   . LEU A 1 401 ? 166.326 149.178 176.406 1.00 33.28  ? 401 LEU A O   1 
ATOM   2927  C  CB  . LEU A 1 401 ? 166.264 151.481 178.485 1.00 33.28  ? 401 LEU A CB  1 
ATOM   2928  C  CG  . LEU A 1 401 ? 165.660 152.562 179.379 1.00 33.28  ? 401 LEU A CG  1 
ATOM   2929  C  CD1 . LEU A 1 401 ? 166.077 152.361 180.822 1.00 33.28  ? 401 LEU A CD1 1 
ATOM   2930  C  CD2 . LEU A 1 401 ? 166.090 153.927 178.898 1.00 33.28  ? 401 LEU A CD2 1 
ATOM   2931  N  N   . GLY A 1 402 ? 167.386 150.885 175.392 1.00 39.46  ? 402 GLY A N   1 
ATOM   2932  C  CA  . GLY A 1 402 ? 168.341 150.033 174.710 1.00 39.46  ? 402 GLY A CA  1 
ATOM   2933  C  C   . GLY A 1 402 ? 167.704 148.997 173.799 1.00 39.46  ? 402 GLY A C   1 
ATOM   2934  O  O   . GLY A 1 402 ? 166.783 149.274 173.024 1.00 39.46  ? 402 GLY A O   1 
ATOM   2935  N  N   . GLY A 1 403 ? 168.219 147.780 173.901 1.00 45.49  ? 403 GLY A N   1 
ATOM   2936  C  CA  . GLY A 1 403 ? 167.784 146.672 173.082 1.00 45.49  ? 403 GLY A CA  1 
ATOM   2937  C  C   . GLY A 1 403 ? 168.725 146.413 171.923 1.00 45.49  ? 403 GLY A C   1 
ATOM   2938  O  O   . GLY A 1 403 ? 169.952 146.420 172.056 1.00 45.49  ? 403 GLY A O   1 
ATOM   2939  N  N   . GLU A 1 404 ? 168.127 146.174 170.758 1.00 52.74  ? 404 GLU A N   1 
ATOM   2940  C  CA  . GLU A 1 404 ? 168.888 146.021 169.524 1.00 52.74  ? 404 GLU A CA  1 
ATOM   2941  C  C   . GLU A 1 404 ? 167.962 146.274 168.344 1.00 52.74  ? 404 GLU A C   1 
ATOM   2942  O  O   . GLU A 1 404 ? 166.871 145.702 168.273 1.00 52.74  ? 404 GLU A O   1 
ATOM   2943  C  CB  . GLU A 1 404 ? 169.537 144.633 169.441 1.00 52.74  ? 404 GLU A CB  1 
ATOM   2944  C  CG  . GLU A 1 404 ? 168.574 143.464 169.445 1.00 52.74  ? 404 GLU A CG  1 
ATOM   2945  C  CD  . GLU A 1 404 ? 169.293 142.133 169.435 1.00 52.74  ? 404 GLU A CD  1 
ATOM   2946  O  OE1 . GLU A 1 404 ? 170.541 142.135 169.444 1.00 52.74  ? 404 GLU A OE1 1 
ATOM   2947  O  OE2 . GLU A 1 404 ? 168.613 141.086 169.419 1.00 52.74  ? 404 GLU A OE2 1 
ATOM   2948  N  N   . GLU A 1 405 ? 168.388 147.148 167.440 1.00 56.49  ? 405 GLU A N   1 
ATOM   2949  C  CA  . GLU A 1 405 ? 167.599 147.533 166.283 1.00 56.49  ? 405 GLU A CA  1 
ATOM   2950  C  C   . GLU A 1 405 ? 168.238 146.996 165.011 1.00 56.49  ? 405 GLU A C   1 
ATOM   2951  O  O   . GLU A 1 405 ? 169.457 146.830 164.923 1.00 56.49  ? 405 GLU A O   1 
ATOM   2952  C  CB  . GLU A 1 405 ? 167.461 149.056 166.195 1.00 56.49  ? 405 GLU A CB  1 
ATOM   2953  C  CG  . GLU A 1 405 ? 168.777 149.776 165.954 1.00 56.49  ? 405 GLU A CG  1 
ATOM   2954  C  CD  . GLU A 1 405 ? 168.621 151.281 165.903 1.00 56.49  ? 405 GLU A CD  1 
ATOM   2955  O  OE1 . GLU A 1 405 ? 167.482 151.767 166.056 1.00 56.49  ? 405 GLU A OE1 1 
ATOM   2956  O  OE2 . GLU A 1 405 ? 169.639 151.978 165.711 1.00 56.49  ? 405 GLU A OE2 1 
ATOM   2957  N  N   . ASN A 1 406 ? 167.396 146.727 164.018 1.00 59.30  ? 406 ASN A N   1 
ATOM   2958  C  CA  . ASN A 1 406 ? 167.840 146.183 162.743 1.00 59.30  ? 406 ASN A CA  1 
ATOM   2959  C  C   . ASN A 1 406 ? 168.718 147.200 162.027 1.00 59.30  ? 406 ASN A C   1 
ATOM   2960  O  O   . ASN A 1 406 ? 168.521 148.410 162.172 1.00 59.30  ? 406 ASN A O   1 
ATOM   2961  C  CB  . ASN A 1 406 ? 166.645 145.772 161.879 1.00 59.30  ? 406 ASN A CB  1 
ATOM   2962  C  CG  . ASN A 1 406 ? 165.644 146.893 161.680 1.00 59.30  ? 406 ASN A CG  1 
ATOM   2963  O  OD1 . ASN A 1 406 ? 165.861 148.027 162.102 1.00 59.30  ? 406 ASN A OD1 1 
ATOM   2964  N  ND2 . ASN A 1 406 ? 164.526 146.572 161.039 1.00 59.30  ? 406 ASN A ND2 1 
ATOM   2965  N  N   . ASP A 1 407 ? 169.696 146.708 161.271 1.00 62.05  ? 407 ASP A N   1 
ATOM   2966  C  CA  . ASP A 1 407 ? 170.711 147.579 160.698 1.00 62.05  ? 407 ASP A CA  1 
ATOM   2967  C  C   . ASP A 1 407 ? 170.809 147.351 159.197 1.00 62.05  ? 407 ASP A C   1 
ATOM   2968  O  O   . ASP A 1 407 ? 169.796 147.303 158.495 1.00 62.05  ? 407 ASP A O   1 
ATOM   2969  C  CB  . ASP A 1 407 ? 172.072 147.358 161.373 1.00 62.05  ? 407 ASP A CB  1 
ATOM   2970  C  CG  . ASP A 1 407 ? 172.550 145.919 161.282 1.00 62.05  ? 407 ASP A CG  1 
ATOM   2971  O  OD1 . ASP A 1 407 ? 171.809 145.073 160.741 1.00 62.05  ? 407 ASP A OD1 1 
ATOM   2972  O  OD2 . ASP A 1 407 ? 173.672 145.635 161.748 1.00 62.05  ? 407 ASP A OD2 1 
ATOM   2973  N  N   . LEU A 1 408 ? 172.048 147.223 158.721 1.00 62.84  ? 408 LEU A N   1 
ATOM   2974  C  CA  . LEU A 1 408 ? 172.369 147.102 157.301 1.00 62.84  ? 408 LEU A CA  1 
ATOM   2975  C  C   . LEU A 1 408 ? 172.773 145.663 156.961 1.00 62.84  ? 408 LEU A C   1 
ATOM   2976  O  O   . LEU A 1 408 ? 173.888 145.212 157.231 1.00 62.84  ? 408 LEU A O   1 
ATOM   2977  C  CB  . LEU A 1 408 ? 173.468 148.109 156.933 1.00 62.84  ? 408 LEU A CB  1 
ATOM   2978  C  CG  . LEU A 1 408 ? 173.884 148.326 155.479 1.00 62.84  ? 408 LEU A CG  1 
ATOM   2979  C  CD1 . LEU A 1 408 ? 174.329 149.764 155.282 1.00 62.84  ? 408 LEU A CD1 1 
ATOM   2980  C  CD2 . LEU A 1 408 ? 175.003 147.379 155.085 1.00 62.84  ? 408 LEU A CD2 1 
ATOM   2981  N  N   . ASP A 1 409 ? 171.825 144.948 156.359 1.00 61.73  ? 409 ASP A N   1 
ATOM   2982  C  CA  . ASP A 1 409 ? 170.512 145.493 156.032 1.00 61.73  ? 409 ASP A CA  1 
ATOM   2983  C  C   . ASP A 1 409 ? 169.419 144.544 156.516 1.00 61.73  ? 409 ASP A C   1 
ATOM   2984  O  O   . ASP A 1 409 ? 168.274 144.943 156.725 1.00 61.73  ? 409 ASP A O   1 
ATOM   2985  C  CB  . ASP A 1 409 ? 170.392 145.725 154.525 1.00 61.73  ? 409 ASP A CB  1 
ATOM   2986  C  CG  . ASP A 1 409 ? 169.218 146.613 154.157 1.00 61.73  ? 409 ASP A CG  1 
ATOM   2987  O  OD1 . ASP A 1 409 ? 168.491 147.061 155.065 1.00 61.73  ? 409 ASP A OD1 1 
ATOM   2988  O  OD2 . ASP A 1 409 ? 169.026 146.867 152.949 1.00 61.73  ? 409 ASP A OD2 1 
ATOM   2989  N  N   . PHE A 1 410 ? 169.789 143.277 156.700 1.00 59.66  ? 410 PHE A N   1 
ATOM   2990  C  CA  . PHE A 1 410 ? 168.863 142.244 157.136 1.00 59.66  ? 410 PHE A CA  1 
ATOM   2991  C  C   . PHE A 1 410 ? 169.008 141.890 158.608 1.00 59.66  ? 410 PHE A C   1 
ATOM   2992  O  O   . PHE A 1 410 ? 168.128 141.218 159.155 1.00 59.66  ? 410 PHE A O   1 
ATOM   2993  C  CB  . PHE A 1 410 ? 169.066 140.967 156.306 1.00 59.66  ? 410 PHE A CB  1 
ATOM   2994  C  CG  . PHE A 1 410 ? 168.830 141.152 154.838 1.00 59.66  ? 410 PHE A CG  1 
ATOM   2995  C  CD1 . PHE A 1 410 ? 167.551 141.140 154.317 1.00 59.66  ? 410 PHE A CD1 1 
ATOM   2996  C  CD2 . PHE A 1 410 ? 169.895 141.338 153.975 1.00 59.66  ? 410 PHE A CD2 1 
ATOM   2997  C  CE1 . PHE A 1 410 ? 167.338 141.312 152.965 1.00 59.66  ? 410 PHE A CE1 1 
ATOM   2998  C  CE2 . PHE A 1 410 ? 169.687 141.509 152.624 1.00 59.66  ? 410 PHE A CE2 1 
ATOM   2999  C  CZ  . PHE A 1 410 ? 168.407 141.495 152.119 1.00 59.66  ? 410 PHE A CZ  1 
ATOM   3000  N  N   . PHE A 1 411 ? 170.080 142.325 159.258 1.00 57.89  ? 411 PHE A N   1 
ATOM   3001  C  CA  . PHE A 1 411 ? 170.481 141.804 160.553 1.00 57.89  ? 411 PHE A CA  1 
ATOM   3002  C  C   . PHE A 1 411 ? 170.085 142.764 161.670 1.00 57.89  ? 411 PHE A C   1 
ATOM   3003  O  O   . PHE A 1 411 ? 169.195 143.602 161.520 1.00 57.89  ? 411 PHE A O   1 
ATOM   3004  C  CB  . PHE A 1 411 ? 171.988 141.552 160.556 1.00 57.89  ? 411 PHE A CB  1 
ATOM   3005  C  CG  . PHE A 1 411 ? 172.436 140.615 159.474 1.00 57.89  ? 411 PHE A CG  1 
ATOM   3006  C  CD1 . PHE A 1 411 ? 172.318 139.246 159.624 1.00 57.89  ? 411 PHE A CD1 1 
ATOM   3007  C  CD2 . PHE A 1 411 ? 172.958 141.109 158.292 1.00 57.89  ? 411 PHE A CD2 1 
ATOM   3008  C  CE1 . PHE A 1 411 ? 172.728 138.388 158.621 1.00 57.89  ? 411 PHE A CE1 1 
ATOM   3009  C  CE2 . PHE A 1 411 ? 173.367 140.258 157.288 1.00 57.89  ? 411 PHE A CE2 1 
ATOM   3010  C  CZ  . PHE A 1 411 ? 173.252 138.896 157.452 1.00 57.89  ? 411 PHE A CZ  1 
ATOM   3011  N  N   . THR A 1 412 ? 170.762 142.627 162.808 1.00 55.97  ? 412 THR A N   1 
ATOM   3012  C  CA  . THR A 1 412 ? 170.506 143.442 163.986 1.00 55.97  ? 412 THR A CA  1 
ATOM   3013  C  C   . THR A 1 412 ? 171.815 143.957 164.575 1.00 55.97  ? 412 THR A C   1 
ATOM   3014  O  O   . THR A 1 412 ? 172.876 143.352 164.400 1.00 55.97  ? 412 THR A O   1 
ATOM   3015  C  CB  . THR A 1 412 ? 169.747 142.651 165.057 1.00 55.97  ? 412 THR A CB  1 
ATOM   3016  O  OG1 . THR A 1 412 ? 170.538 141.533 165.476 1.00 55.97  ? 412 THR A OG1 1 
ATOM   3017  C  CG2 . THR A 1 412 ? 168.413 142.152 164.523 1.00 55.97  ? 412 THR A CG2 1 
ATOM   3018  N  N   . LYS A 1 413 ? 171.724 145.080 165.281 1.00 57.55  ? 413 LYS A N   1 
ATOM   3019  C  CA  . LYS A 1 413 ? 172.846 145.700 165.965 1.00 57.55  ? 413 LYS A CA  1 
ATOM   3020  C  C   . LYS A 1 413 ? 172.397 146.219 167.322 1.00 57.55  ? 413 LYS A C   1 
ATOM   3021  O  O   . LYS A 1 413 ? 171.232 146.591 167.493 1.00 57.55  ? 413 LYS A O   1 
ATOM   3022  C  CB  . LYS A 1 413 ? 173.435 146.857 165.144 1.00 57.55  ? 413 LYS A CB  1 
ATOM   3023  C  CG  . LYS A 1 413 ? 172.529 148.073 165.033 1.00 57.55  ? 413 LYS A CG  1 
ATOM   3024  C  CD  . LYS A 1 413 ? 173.194 149.190 164.245 1.00 57.55  ? 413 LYS A CD  1 
ATOM   3025  C  CE  . LYS A 1 413 ? 172.265 150.381 164.087 1.00 57.55  ? 413 LYS A CE  1 
ATOM   3026  N  NZ  . LYS A 1 413 ? 171.978 151.034 165.393 1.00 57.55  ? 413 LYS A NZ  1 
ATOM   3027  N  N   . PRO A 1 414 ? 173.295 146.251 168.306 1.00 54.25  ? 414 PRO A N   1 
ATOM   3028  C  CA  . PRO A 1 414 ? 172.921 146.786 169.619 1.00 54.25  ? 414 PRO A CA  1 
ATOM   3029  C  C   . PRO A 1 414 ? 172.673 148.285 169.560 1.00 54.25  ? 414 PRO A C   1 
ATOM   3030  O  O   . PRO A 1 414 ? 173.561 149.075 169.233 1.00 54.25  ? 414 PRO A O   1 
ATOM   3031  C  CB  . PRO A 1 414 ? 174.131 146.450 170.496 1.00 54.25  ? 414 PRO A CB  1 
ATOM   3032  C  CG  . PRO A 1 414 ? 175.266 146.341 169.543 1.00 54.25  ? 414 PRO A CG  1 
ATOM   3033  C  CD  . PRO A 1 414 ? 174.688 145.773 168.281 1.00 54.25  ? 414 PRO A CD  1 
ATOM   3034  N  N   . SER A 1 415 ? 171.443 148.672 169.889 1.00 47.60  ? 415 SER A N   1 
ATOM   3035  C  CA  . SER A 1 415 ? 170.997 150.053 169.789 1.00 47.60  ? 415 SER A CA  1 
ATOM   3036  C  C   . SER A 1 415 ? 171.315 150.801 171.076 1.00 47.60  ? 415 SER A C   1 
ATOM   3037  O  O   . SER A 1 415 ? 171.796 150.231 172.057 1.00 47.60  ? 415 SER A O   1 
ATOM   3038  C  CB  . SER A 1 415 ? 169.494 150.137 169.498 1.00 47.60  ? 415 SER A CB  1 
ATOM   3039  O  OG  . SER A 1 415 ? 168.737 149.660 170.595 1.00 47.60  ? 415 SER A OG  1 
ATOM   3040  N  N   . ARG A 1 416 ? 171.031 152.101 171.053 1.00 40.46  ? 416 ARG A N   1 
ATOM   3041  C  CA  . ARG A 1 416 ? 171.219 153.004 172.180 1.00 40.46  ? 416 ARG A CA  1 
ATOM   3042  C  C   . ARG A 1 416 ? 170.006 153.906 172.336 1.00 40.46  ? 416 ARG A C   1 
ATOM   3043  O  O   . ARG A 1 416 ? 170.025 154.884 173.088 1.00 40.46  ? 416 ARG A O   1 
ATOM   3044  C  CB  . ARG A 1 416 ? 172.477 153.848 172.002 1.00 40.46  ? 416 ARG A CB  1 
ATOM   3045  C  CG  . ARG A 1 416 ? 173.769 153.070 172.008 1.00 40.46  ? 416 ARG A CG  1 
ATOM   3046  C  CD  . ARG A 1 416 ? 174.952 153.998 171.821 1.00 40.46  ? 416 ARG A CD  1 
ATOM   3047  N  NE  . ARG A 1 416 ? 176.216 153.272 171.784 1.00 40.46  ? 416 ARG A NE  1 
ATOM   3048  C  CZ  . ARG A 1 416 ? 177.397 153.846 171.588 1.00 40.46  ? 416 ARG A CZ  1 
ATOM   3049  N  NH1 . ARG A 1 416 ? 177.478 155.157 171.413 1.00 40.46  ? 416 ARG A NH1 1 
ATOM   3050  N  NH2 . ARG A 1 416 ? 178.498 153.108 171.568 1.00 40.46  ? 416 ARG A NH2 1 
ATOM   3051  N  N   . LEU A 1 417 ? 168.931 153.586 171.622 1.00 38.31  ? 417 LEU A N   1 
ATOM   3052  C  CA  . LEU A 1 417 ? 167.804 154.497 171.505 1.00 38.31  ? 417 LEU A CA  1 
ATOM   3053  C  C   . LEU A 1 417 ? 167.045 154.608 172.822 1.00 38.31  ? 417 LEU A C   1 
ATOM   3054  O  O   . LEU A 1 417 ? 167.041 153.689 173.645 1.00 38.31  ? 417 LEU A O   1 
ATOM   3055  C  CB  . LEU A 1 417 ? 166.852 154.032 170.402 1.00 38.31  ? 417 LEU A CB  1 
ATOM   3056  C  CG  . LEU A 1 417 ? 167.183 154.393 168.950 1.00 38.31  ? 417 LEU A CG  1 
ATOM   3057  C  CD1 . LEU A 1 417 ? 167.249 155.900 168.771 1.00 38.31  ? 417 LEU A CD1 1 
ATOM   3058  C  CD2 . LEU A 1 417 ? 168.467 153.730 168.467 1.00 38.31  ? 417 LEU A CD2 1 
ATOM   3059  N  N   . ILE A 1 418 ? 166.401 155.758 173.012 1.00 37.83  ? 418 ILE A N   1 
ATOM   3060  C  CA  . ILE A 1 418 ? 165.514 155.982 174.147 1.00 37.83  ? 418 ILE A CA  1 
ATOM   3061  C  C   . ILE A 1 418 ? 164.110 156.203 173.607 1.00 37.83  ? 418 ILE A C   1 
ATOM   3062  O  O   . ILE A 1 418 ? 163.907 157.011 172.694 1.00 37.83  ? 418 ILE A O   1 
ATOM   3063  C  CB  . ILE A 1 418 ? 165.964 157.182 174.997 1.00 37.83  ? 418 ILE A CB  1 
ATOM   3064  C  CG1 . ILE A 1 418 ? 167.423 157.039 175.414 1.00 37.83  ? 418 ILE A CG1 1 
ATOM   3065  C  CG2 . ILE A 1 418 ? 165.104 157.286 176.239 1.00 37.83  ? 418 ILE A CG2 1 
ATOM   3066  C  CD1 . ILE A 1 418 ? 167.676 155.856 176.279 1.00 37.83  ? 418 ILE A CD1 1 
ATOM   3067  N  N   . GLN A 1 419 ? 163.132 155.489 174.155 1.00 41.62  ? 419 GLN A N   1 
ATOM   3068  C  CA  . GLN A 1 419 ? 161.752 155.688 173.737 1.00 41.62  ? 419 GLN A CA  1 
ATOM   3069  C  C   . GLN A 1 419 ? 160.853 155.859 174.951 1.00 41.62  ? 419 GLN A C   1 
ATOM   3070  O  O   . GLN A 1 419 ? 160.963 155.116 175.930 1.00 41.62  ? 419 GLN A O   1 
ATOM   3071  C  CB  . GLN A 1 419 ? 161.272 154.508 172.896 1.00 41.62  ? 419 GLN A CB  1 
ATOM   3072  C  CG  . GLN A 1 419 ? 161.945 154.373 171.549 1.00 41.62  ? 419 GLN A CG  1 
ATOM   3073  C  CD  . GLN A 1 419 ? 161.424 153.184 170.774 1.00 41.62  ? 419 GLN A CD  1 
ATOM   3074  O  OE1 . GLN A 1 419 ? 160.595 152.423 171.269 1.00 41.62  ? 419 GLN A OE1 1 
ATOM   3075  N  NE2 . GLN A 1 419 ? 161.906 153.017 169.553 1.00 41.62  ? 419 GLN A NE2 1 
ATOM   3076  N  N   . CYS A 1 420 ? 159.960 156.842 174.888 1.00 47.02  ? 420 CYS A N   1 
ATOM   3077  C  CA  . CYS A 1 420 ? 158.980 157.073 175.946 1.00 47.02  ? 420 CYS A CA  1 
ATOM   3078  C  C   . CYS A 1 420 ? 157.604 156.756 175.371 1.00 47.02  ? 420 CYS A C   1 
ATOM   3079  O  O   . CYS A 1 420 ? 157.206 157.312 174.343 1.00 47.02  ? 420 CYS A O   1 
ATOM   3080  C  CB  . CYS A 1 420 ? 159.060 158.500 176.480 1.00 47.02  ? 420 CYS A CB  1 
ATOM   3081  S  SG  . CYS A 1 420 ? 158.617 159.801 175.317 1.00 47.02  ? 420 CYS A SG  1 
ATOM   3082  N  N   . PHE A 1 421 ? 156.884 155.847 176.019 1.00 50.72  ? 421 PHE A N   1 
ATOM   3083  C  CA  . PHE A 1 421 ? 155.557 155.475 175.557 1.00 50.72  ? 421 PHE A CA  1 
ATOM   3084  C  C   . PHE A 1 421 ? 154.512 156.015 176.522 1.00 50.72  ? 421 PHE A C   1 
ATOM   3085  O  O   . PHE A 1 421 ? 154.133 155.339 177.483 1.00 50.72  ? 421 PHE A O   1 
ATOM   3086  C  CB  . PHE A 1 421 ? 155.434 153.957 175.438 1.00 50.72  ? 421 PHE A CB  1 
ATOM   3087  C  CG  . PHE A 1 421 ? 154.138 153.504 174.834 1.00 50.72  ? 421 PHE A CG  1 
ATOM   3088  C  CD1 . PHE A 1 421 ? 153.935 153.585 173.470 1.00 50.72  ? 421 PHE A CD1 1 
ATOM   3089  C  CD2 . PHE A 1 421 ? 153.121 153.006 175.628 1.00 50.72  ? 421 PHE A CD2 1 
ATOM   3090  C  CE1 . PHE A 1 421 ? 152.750 153.173 172.909 1.00 50.72  ? 421 PHE A CE1 1 
ATOM   3091  C  CE2 . PHE A 1 421 ? 151.932 152.594 175.069 1.00 50.72  ? 421 PHE A CE2 1 
ATOM   3092  C  CZ  . PHE A 1 421 ? 151.747 152.678 173.709 1.00 50.72  ? 421 PHE A CZ  1 
ATOM   3093  N  N   . ASP A 1 422 ? 154.059 157.239 176.269 1.00 57.78  ? 422 ASP A N   1 
ATOM   3094  C  CA  . ASP A 1 422 ? 153.089 157.918 177.115 1.00 57.78  ? 422 ASP A CA  1 
ATOM   3095  C  C   . ASP A 1 422 ? 151.836 157.060 177.225 1.00 57.78  ? 422 ASP A C   1 
ATOM   3096  O  O   . ASP A 1 422 ? 151.027 157.012 176.294 1.00 57.78  ? 422 ASP A O   1 
ATOM   3097  C  CB  . ASP A 1 422 ? 152.754 159.298 176.547 1.00 57.78  ? 422 ASP A CB  1 
ATOM   3098  C  CG  . ASP A 1 422 ? 151.986 160.163 177.525 1.00 57.78  ? 422 ASP A CG  1 
ATOM   3099  O  OD1 . ASP A 1 422 ? 151.678 159.685 178.636 1.00 57.78  ? 422 ASP A OD1 1 
ATOM   3100  O  OD2 . ASP A 1 422 ? 151.695 161.327 177.182 1.00 57.78  ? 422 ASP A OD2 1 
ATOM   3101  N  N   . THR A 1 423 ? 151.687 156.383 178.361 1.00 58.56  ? 423 THR A N   1 
ATOM   3102  C  CA  . THR A 1 423 ? 150.634 155.397 178.570 1.00 58.56  ? 423 THR A CA  1 
ATOM   3103  C  C   . THR A 1 423 ? 149.228 155.968 178.448 1.00 58.56  ? 423 THR A C   1 
ATOM   3104  O  O   . THR A 1 423 ? 148.291 155.209 178.182 1.00 58.56  ? 423 THR A O   1 
ATOM   3105  C  CB  . THR A 1 423 ? 150.794 154.737 179.944 1.00 58.56  ? 423 THR A CB  1 
ATOM   3106  O  OG1 . THR A 1 423 ? 149.851 153.666 180.072 1.00 58.56  ? 423 THR A OG1 1 
ATOM   3107  C  CG2 . THR A 1 423 ? 150.551 155.745 181.054 1.00 58.56  ? 423 THR A CG2 1 
ATOM   3108  N  N   . GLU A 1 424 ? 149.050 157.274 178.633 1.00 64.81  ? 424 GLU A N   1 
ATOM   3109  C  CA  . GLU A 1 424 ? 147.731 157.891 178.592 1.00 64.81  ? 424 GLU A CA  1 
ATOM   3110  C  C   . GLU A 1 424 ? 147.382 158.444 177.219 1.00 64.81  ? 424 GLU A C   1 
ATOM   3111  O  O   . GLU A 1 424 ? 146.430 157.978 176.586 1.00 64.81  ? 424 GLU A O   1 
ATOM   3112  C  CB  . GLU A 1 424 ? 147.641 159.009 179.640 1.00 64.81  ? 424 GLU A CB  1 
ATOM   3113  C  CG  . GLU A 1 424 ? 147.760 158.515 181.069 1.00 64.81  ? 424 GLU A CG  1 
ATOM   3114  C  CD  . GLU A 1 424 ? 146.601 157.629 181.477 1.00 64.81  ? 424 GLU A CD  1 
ATOM   3115  O  OE1 . GLU A 1 424 ? 145.477 157.852 180.980 1.00 64.81  ? 424 GLU A OE1 1 
ATOM   3116  O  OE2 . GLU A 1 424 ? 146.815 156.707 182.291 1.00 64.81  ? 424 GLU A OE2 1 
ATOM   3117  N  N   . THR A 1 425 ? 148.135 159.431 176.742 1.00 65.44  ? 425 THR A N   1 
ATOM   3118  C  CA  . THR A 1 425 ? 147.906 160.026 175.434 1.00 65.44  ? 425 THR A CA  1 
ATOM   3119  C  C   . THR A 1 425 ? 148.216 159.060 174.294 1.00 65.44  ? 425 THR A C   1 
ATOM   3120  O  O   . THR A 1 425 ? 147.792 159.305 173.158 1.00 65.44  ? 425 THR A O   1 
ATOM   3121  C  CB  . THR A 1 425 ? 148.753 161.301 175.298 1.00 65.44  ? 425 THR A CB  1 
ATOM   3122  O  OG1 . THR A 1 425 ? 148.546 162.127 176.449 1.00 65.44  ? 425 THR A OG1 1 
ATOM   3123  C  CG2 . THR A 1 425 ? 148.342 162.106 174.075 1.00 65.44  ? 425 THR A CG2 1 
ATOM   3124  N  N   . ASP A 1 426 ? 148.924 157.964 174.579 1.00 65.13  ? 426 ASP A N   1 
ATOM   3125  C  CA  . ASP A 1 426 ? 149.277 156.947 173.585 1.00 65.13  ? 426 ASP A CA  1 
ATOM   3126  C  C   . ASP A 1 426 ? 150.199 157.519 172.512 1.00 65.13  ? 426 ASP A C   1 
ATOM   3127  O  O   . ASP A 1 426 ? 149.981 157.330 171.314 1.00 65.13  ? 426 ASP A O   1 
ATOM   3128  C  CB  . ASP A 1 426 ? 148.031 156.318 172.956 1.00 65.13  ? 426 ASP A CB  1 
ATOM   3129  C  CG  . ASP A 1 426 ? 147.247 155.470 173.937 1.00 65.13  ? 426 ASP A CG  1 
ATOM   3130  O  OD1 . ASP A 1 426 ? 147.862 154.927 174.878 1.00 65.13  ? 426 ASP A OD1 1 
ATOM   3131  O  OD2 . ASP A 1 426 ? 146.018 155.341 173.765 1.00 65.13  ? 426 ASP A OD2 1 
ATOM   3132  N  N   . LYS A 1 427 ? 151.244 158.220 172.945 1.00 63.45  ? 427 LYS A N   1 
ATOM   3133  C  CA  . LYS A 1 427 ? 152.222 158.827 172.047 1.00 63.45  ? 427 LYS A CA  1 
ATOM   3134  C  C   . LYS A 1 427 ? 153.586 158.209 172.323 1.00 63.45  ? 427 LYS A C   1 
ATOM   3135  O  O   . LYS A 1 427 ? 154.091 158.285 173.447 1.00 63.45  ? 427 LYS A O   1 
ATOM   3136  C  CB  . LYS A 1 427 ? 152.270 160.343 172.225 1.00 63.45  ? 427 LYS A CB  1 
ATOM   3137  C  CG  . LYS A 1 427 ? 150.975 161.057 171.894 1.00 63.45  ? 427 LYS A CG  1 
ATOM   3138  C  CD  . LYS A 1 427 ? 150.654 160.966 170.413 1.00 63.45  ? 427 LYS A CD  1 
ATOM   3139  C  CE  . LYS A 1 427 ? 149.459 161.835 170.056 1.00 63.45  ? 427 LYS A CE  1 
ATOM   3140  N  NZ  . LYS A 1 427 ? 148.192 161.304 170.626 1.00 63.45  ? 427 LYS A NZ  1 
ATOM   3141  N  N   . CYS A 1 428 ? 154.179 157.604 171.299 1.00 57.55  ? 428 CYS A N   1 
ATOM   3142  C  CA  . CYS A 1 428 ? 155.527 157.055 171.393 1.00 57.55  ? 428 CYS A CA  1 
ATOM   3143  C  C   . CYS A 1 428 ? 156.437 157.866 170.480 1.00 57.55  ? 428 CYS A C   1 
ATOM   3144  O  O   . CYS A 1 428 ? 156.141 158.038 169.294 1.00 57.55  ? 428 CYS A O   1 
ATOM   3145  C  CB  . CYS A 1 428 ? 155.539 155.578 171.010 1.00 57.55  ? 428 CYS A CB  1 
ATOM   3146  S  SG  . CYS A 1 428 ? 157.164 154.800 171.116 1.00 57.55  ? 428 CYS A SG  1 
ATOM   3147  N  N   . HIS A 1 429 ? 157.535 158.374 171.031 1.00 50.71  ? 429 HIS A N   1 
ATOM   3148  C  CA  . HIS A 1 429 ? 158.503 159.141 170.266 1.00 50.71  ? 429 HIS A CA  1 
ATOM   3149  C  C   . HIS A 1 429 ? 159.893 159.000 170.869 1.00 50.71  ? 429 HIS A C   1 
ATOM   3150  O  O   . HIS A 1 429 ? 160.053 158.853 172.084 1.00 50.71  ? 429 HIS A O   1 
ATOM   3151  C  CB  . HIS A 1 429 ? 158.099 160.620 170.178 1.00 50.71  ? 429 HIS A CB  1 
ATOM   3152  C  CG  . HIS A 1 429 ? 157.933 161.288 171.506 1.00 50.71  ? 429 HIS A CG  1 
ATOM   3153  N  ND1 . HIS A 1 429 ? 156.778 161.178 172.251 1.00 50.71  ? 429 HIS A ND1 1 
ATOM   3154  C  CD2 . HIS A 1 429 ? 158.764 162.086 172.216 1.00 50.71  ? 429 HIS A CD2 1 
ATOM   3155  C  CE1 . HIS A 1 429 ? 156.908 161.876 173.365 1.00 50.71  ? 429 HIS A CE1 1 
ATOM   3156  N  NE2 . HIS A 1 429 ? 158.105 162.435 173.370 1.00 50.71  ? 429 HIS A NE2 1 
ATOM   3157  N  N   . VAL A 1 430 ? 160.895 159.043 169.997 1.00 46.20  ? 430 VAL A N   1 
ATOM   3158  C  CA  . VAL A 1 430 ? 162.282 158.790 170.365 1.00 46.20  ? 430 VAL A CA  1 
ATOM   3159  C  C   . VAL A 1 430 ? 162.877 160.054 170.971 1.00 46.20  ? 430 VAL A C   1 
ATOM   3160  O  O   . VAL A 1 430 ? 162.568 161.169 170.535 1.00 46.20  ? 430 VAL A O   1 
ATOM   3161  C  CB  . VAL A 1 430 ? 163.091 158.331 169.139 1.00 46.20  ? 430 VAL A CB  1 
ATOM   3162  C  CG1 . VAL A 1 430 ? 164.550 158.119 169.499 1.00 46.20  ? 430 VAL A CG1 1 
ATOM   3163  C  CG2 . VAL A 1 430 ? 162.490 157.065 168.552 1.00 46.20  ? 430 VAL A CG2 1 
ATOM   3164  N  N   . LYS A 1 431 ? 163.730 159.883 171.977 1.00 39.68  ? 431 LYS A N   1 
ATOM   3165  C  CA  . LYS A 1 431 ? 164.393 161.025 172.584 1.00 39.68  ? 431 LYS A CA  1 
ATOM   3166  C  C   . LYS A 1 431 ? 165.602 161.437 171.744 1.00 39.68  ? 431 LYS A C   1 
ATOM   3167  O  O   . LYS A 1 431 ? 166.305 160.579 171.202 1.00 39.68  ? 431 LYS A O   1 
ATOM   3168  C  CB  . LYS A 1 431 ? 164.831 160.696 174.009 1.00 39.68  ? 431 LYS A CB  1 
ATOM   3169  C  CG  . LYS A 1 431 ? 163.688 160.341 174.938 1.00 39.68  ? 431 LYS A CG  1 
ATOM   3170  C  CD  . LYS A 1 431 ? 162.767 161.522 175.152 1.00 39.68  ? 431 LYS A CD  1 
ATOM   3171  C  CE  . LYS A 1 431 ? 161.677 161.194 176.151 1.00 39.68  ? 431 LYS A CE  1 
ATOM   3172  N  NZ  . LYS A 1 431 ? 160.709 162.316 176.315 1.00 39.68  ? 431 LYS A NZ  1 
ATOM   3173  N  N   . PRO A 1 432 ? 165.872 162.741 171.623 1.00 38.10  ? 432 PRO A N   1 
ATOM   3174  C  CA  . PRO A 1 432 ? 166.964 163.180 170.736 1.00 38.10  ? 432 PRO A CA  1 
ATOM   3175  C  C   . PRO A 1 432 ? 168.357 162.916 171.283 1.00 38.10  ? 432 PRO A C   1 
ATOM   3176  O  O   . PRO A 1 432 ? 169.248 163.757 171.105 1.00 38.10  ? 432 PRO A O   1 
ATOM   3177  C  CB  . PRO A 1 432 ? 166.702 164.686 170.589 1.00 38.10  ? 432 PRO A CB  1 
ATOM   3178  C  CG  . PRO A 1 432 ? 165.269 164.874 170.963 1.00 38.10  ? 432 PRO A CG  1 
ATOM   3179  C  CD  . PRO A 1 432 ? 165.013 163.863 172.032 1.00 38.10  ? 432 PRO A CD  1 
ATOM   3180  N  N   . TYR A 1 433 ? 168.580 161.779 171.935 1.00 34.81  ? 433 TYR A N   1 
ATOM   3181  C  CA  . TYR A 1 433 ? 169.895 161.445 172.457 1.00 34.81  ? 433 TYR A CA  1 
ATOM   3182  C  C   . TYR A 1 433 ? 169.986 159.953 172.771 1.00 34.81  ? 433 TYR A C   1 
ATOM   3183  O  O   . TYR A 1 433 ? 168.985 159.233 172.814 1.00 34.81  ? 433 TYR A O   1 
ATOM   3184  C  CB  . TYR A 1 433 ? 170.210 162.292 173.691 1.00 34.81  ? 433 TYR A CB  1 
ATOM   3185  C  CG  . TYR A 1 433 ? 169.177 162.199 174.791 1.00 34.81  ? 433 TYR A CG  1 
ATOM   3186  C  CD1 . TYR A 1 433 ? 168.097 163.068 174.824 1.00 34.81  ? 433 TYR A CD1 1 
ATOM   3187  C  CD2 . TYR A 1 433 ? 169.282 161.250 175.795 1.00 34.81  ? 433 TYR A CD2 1 
ATOM   3188  C  CE1 . TYR A 1 433 ? 167.152 162.992 175.822 1.00 34.81  ? 433 TYR A CE1 1 
ATOM   3189  C  CE2 . TYR A 1 433 ? 168.338 161.169 176.797 1.00 34.81  ? 433 TYR A CE2 1 
ATOM   3190  C  CZ  . TYR A 1 433 ? 167.277 162.043 176.805 1.00 34.81  ? 433 TYR A CZ  1 
ATOM   3191  O  OH  . TYR A 1 433 ? 166.338 161.964 177.802 1.00 34.81  ? 433 TYR A OH  1 
ATOM   3192  N  N   . VAL A 1 434 ? 171.217 159.485 172.982 1.00 30.78  ? 434 VAL A N   1 
ATOM   3193  C  CA  . VAL A 1 434 ? 171.491 158.063 173.126 1.00 30.78  ? 434 VAL A CA  1 
ATOM   3194  C  C   . VAL A 1 434 ? 172.204 157.802 174.445 1.00 30.78  ? 434 VAL A C   1 
ATOM   3195  O  O   . VAL A 1 434 ? 172.669 158.718 175.126 1.00 30.78  ? 434 VAL A O   1 
ATOM   3196  C  CB  . VAL A 1 434 ? 172.329 157.514 171.953 1.00 30.78  ? 434 VAL A CB  1 
ATOM   3197  C  CG1 . VAL A 1 434 ? 171.581 157.682 170.642 1.00 30.78  ? 434 VAL A CG1 1 
ATOM   3198  C  CG2 . VAL A 1 434 ? 173.682 158.204 171.900 1.00 30.78  ? 434 VAL A CG2 1 
ATOM   3199  N  N   . LEU A 1 435 ? 172.292 156.521 174.787 1.00 33.95  ? 435 LEU A N   1 
ATOM   3200  C  CA  . LEU A 1 435 ? 172.926 156.090 176.017 1.00 33.95  ? 435 LEU A CA  1 
ATOM   3201  C  C   . LEU A 1 435 ? 174.445 156.093 175.869 1.00 33.95  ? 435 LEU A C   1 
ATOM   3202  O  O   . LEU A 1 435 ? 174.969 156.094 174.753 1.00 33.95  ? 435 LEU A O   1 
ATOM   3203  C  CB  . LEU A 1 435 ? 172.442 154.691 176.384 1.00 33.95  ? 435 LEU A CB  1 
ATOM   3204  C  CG  . LEU A 1 435 ? 170.975 154.549 176.777 1.00 33.95  ? 435 LEU A CG  1 
ATOM   3205  C  CD1 . LEU A 1 435 ? 170.598 153.092 176.856 1.00 33.95  ? 435 LEU A CD1 1 
ATOM   3206  C  CD2 . LEU A 1 435 ? 170.730 155.219 178.109 1.00 33.95  ? 435 LEU A CD2 1 
ATOM   3207  N  N   . PRO A 1 436 ? 175.178 156.095 176.985 1.00 36.50  ? 436 PRO A N   1 
ATOM   3208  C  CA  . PRO A 1 436 ? 176.634 155.922 176.917 1.00 36.50  ? 436 PRO A CA  1 
ATOM   3209  C  C   . PRO A 1 436 ? 177.080 154.496 176.627 1.00 36.50  ? 436 PRO A C   1 
ATOM   3210  O  O   . PRO A 1 436 ? 178.288 154.231 176.641 1.00 36.50  ? 436 PRO A O   1 
ATOM   3211  C  CB  . PRO A 1 436 ? 177.095 156.369 178.311 1.00 36.50  ? 436 PRO A CB  1 
ATOM   3212  C  CG  . PRO A 1 436 ? 175.929 156.129 179.183 1.00 36.50  ? 436 PRO A CG  1 
ATOM   3213  C  CD  . PRO A 1 436 ? 174.719 156.397 178.351 1.00 36.50  ? 436 PRO A CD  1 
ATOM   3214  N  N   . PHE A 1 437 ? 176.151 153.578 176.366 1.00 39.83  ? 437 PHE A N   1 
ATOM   3215  C  CA  . PHE A 1 437 ? 176.486 152.205 176.017 1.00 39.83  ? 437 PHE A CA  1 
ATOM   3216  C  C   . PHE A 1 437 ? 175.335 151.591 175.232 1.00 39.83  ? 437 PHE A C   1 
ATOM   3217  O  O   . PHE A 1 437 ? 174.265 152.188 175.092 1.00 39.83  ? 437 PHE A O   1 
ATOM   3218  C  CB  . PHE A 1 437 ? 176.808 151.366 177.260 1.00 39.83  ? 437 PHE A CB  1 
ATOM   3219  C  CG  . PHE A 1 437 ? 175.734 151.398 178.307 1.00 39.83  ? 437 PHE A CG  1 
ATOM   3220  C  CD1 . PHE A 1 437 ? 175.817 152.279 179.367 1.00 39.83  ? 437 PHE A CD1 1 
ATOM   3221  C  CD2 . PHE A 1 437 ? 174.630 150.572 178.219 1.00 39.83  ? 437 PHE A CD2 1 
ATOM   3222  C  CE1 . PHE A 1 437 ? 174.835 152.319 180.325 1.00 39.83  ? 437 PHE A CE1 1 
ATOM   3223  C  CE2 . PHE A 1 437 ? 173.641 150.619 179.176 1.00 39.83  ? 437 PHE A CE2 1 
ATOM   3224  C  CZ  . PHE A 1 437 ? 173.749 151.491 180.230 1.00 39.83  ? 437 PHE A CZ  1 
ATOM   3225  N  N   . ALA A 1 438 ? 175.566 150.381 174.727 1.00 48.03  ? 438 ALA A N   1 
ATOM   3226  C  CA  . ALA A 1 438 ? 174.614 149.689 173.872 1.00 48.03  ? 438 ALA A CA  1 
ATOM   3227  C  C   . ALA A 1 438 ? 174.502 148.230 174.287 1.00 48.03  ? 438 ALA A C   1 
ATOM   3228  O  O   . ALA A 1 438 ? 175.335 147.702 175.029 1.00 48.03  ? 438 ALA A O   1 
ATOM   3229  C  CB  . ALA A 1 438 ? 175.022 149.778 172.398 1.00 48.03  ? 438 ALA A CB  1 
ATOM   3230  N  N   . GLY A 1 439 ? 173.455 147.576 173.791 1.00 48.28  ? 439 GLY A N   1 
ATOM   3231  C  CA  . GLY A 1 439 ? 173.302 146.148 173.978 1.00 48.28  ? 439 GLY A CA  1 
ATOM   3232  C  C   . GLY A 1 439 ? 172.148 145.742 174.867 1.00 48.28  ? 439 GLY A C   1 
ATOM   3233  O  O   . GLY A 1 439 ? 171.134 146.440 174.952 1.00 48.28  ? 439 GLY A O   1 
ATOM   3234  N  N   . ARG A 1 440 ? 172.293 144.597 175.525 1.00 52.92  ? 440 ARG A N   1 
ATOM   3235  C  CA  . ARG A 1 440 ? 171.301 144.087 176.459 1.00 52.92  ? 440 ARG A CA  1 
ATOM   3236  C  C   . ARG A 1 440 ? 171.586 144.663 177.837 1.00 52.92  ? 440 ARG A C   1 
ATOM   3237  O  O   . ARG A 1 440 ? 172.718 144.583 178.325 1.00 52.92  ? 440 ARG A O   1 
ATOM   3238  C  CB  . ARG A 1 440 ? 171.333 142.559 176.500 1.00 52.92  ? 440 ARG A CB  1 
ATOM   3239  C  CG  . ARG A 1 440 ? 170.262 141.926 177.369 1.00 52.92  ? 440 ARG A CG  1 
ATOM   3240  C  CD  . ARG A 1 440 ? 168.874 142.217 176.823 1.00 52.92  ? 440 ARG A CD  1 
ATOM   3241  N  NE  . ARG A 1 440 ? 168.730 141.790 175.433 1.00 52.92  ? 440 ARG A NE  1 
ATOM   3242  C  CZ  . ARG A 1 440 ? 168.428 140.553 175.052 1.00 52.92  ? 440 ARG A CZ  1 
ATOM   3243  N  NH1 . ARG A 1 440 ? 168.236 139.604 175.957 1.00 52.92  ? 440 ARG A NH1 1 
ATOM   3244  N  NH2 . ARG A 1 440 ? 168.320 140.265 173.763 1.00 52.92  ? 440 ARG A NH2 1 
ATOM   3245  N  N   . MET A 1 441 ? 170.563 145.243 178.461 1.00 40.65  ? 441 MET A N   1 
ATOM   3246  C  CA  . MET A 1 441 ? 170.740 145.962 179.712 1.00 40.65  ? 441 MET A CA  1 
ATOM   3247  C  C   . MET A 1 441 ? 169.545 145.715 180.618 1.00 40.65  ? 441 MET A C   1 
ATOM   3248  O  O   . MET A 1 441 ? 168.527 145.159 180.202 1.00 40.65  ? 441 MET A O   1 
ATOM   3249  C  CB  . MET A 1 441 ? 170.929 147.461 179.461 1.00 40.65  ? 441 MET A CB  1 
ATOM   3250  C  CG  . MET A 1 441 ? 169.730 148.133 178.829 1.00 40.65  ? 441 MET A CG  1 
ATOM   3251  S  SD  . MET A 1 441 ? 170.086 149.830 178.357 1.00 40.65  ? 441 MET A SD  1 
ATOM   3252  C  CE  . MET A 1 441 ? 171.137 149.555 176.935 1.00 40.65  ? 441 MET A CE  1 
ATOM   3253  N  N   . HIS A 1 442 ? 169.688 146.135 181.873 1.00 31.55  ? 442 HIS A N   1 
ATOM   3254  C  CA  . HIS A 1 442 ? 168.668 145.949 182.895 1.00 31.55  ? 442 HIS A CA  1 
ATOM   3255  C  C   . HIS A 1 442 ? 168.539 147.243 183.686 1.00 31.55  ? 442 HIS A C   1 
ATOM   3256  O  O   . HIS A 1 442 ? 169.549 147.820 184.106 1.00 31.55  ? 442 HIS A O   1 
ATOM   3257  C  CB  . HIS A 1 442 ? 169.031 144.778 183.814 1.00 31.55  ? 442 HIS A CB  1 
ATOM   3258  C  CG  . HIS A 1 442 ? 167.879 144.243 184.605 1.00 31.55  ? 442 HIS A CG  1 
ATOM   3259  N  ND1 . HIS A 1 442 ? 167.501 144.762 185.825 1.00 31.55  ? 442 HIS A ND1 1 
ATOM   3260  C  CD2 . HIS A 1 442 ? 167.026 143.223 184.352 1.00 31.55  ? 442 HIS A CD2 1 
ATOM   3261  C  CE1 . HIS A 1 442 ? 166.461 144.090 186.284 1.00 31.55  ? 442 HIS A CE1 1 
ATOM   3262  N  NE2 . HIS A 1 442 ? 166.153 143.149 185.410 1.00 31.55  ? 442 HIS A NE2 1 
ATOM   3263  N  N   . ALA A 1 443 ? 167.303 147.700 183.878 1.00 23.87  ? 443 ALA A N   1 
ATOM   3264  C  CA  . ALA A 1 443 ? 167.022 148.986 184.499 1.00 23.87  ? 443 ALA A CA  1 
ATOM   3265  C  C   . ALA A 1 443 ? 166.152 148.803 185.733 1.00 23.87  ? 443 ALA A C   1 
ATOM   3266  O  O   . ALA A 1 443 ? 165.402 147.828 185.837 1.00 23.87  ? 443 ALA A O   1 
ATOM   3267  C  CB  . ALA A 1 443 ? 166.327 149.929 183.516 1.00 23.87  ? 443 ALA A CB  1 
ATOM   3268  N  N   . ALA A 1 444 ? 166.248 149.752 186.662 1.00 22.85  ? 444 ALA A N   1 
ATOM   3269  C  CA  . ALA A 1 444 ? 165.475 149.721 187.897 1.00 22.85  ? 444 ALA A CA  1 
ATOM   3270  C  C   . ALA A 1 444 ? 165.000 151.127 188.219 1.00 22.85  ? 444 ALA A C   1 
ATOM   3271  O  O   . ALA A 1 444 ? 165.819 152.029 188.422 1.00 22.85  ? 444 ALA A O   1 
ATOM   3272  C  CB  . ALA A 1 444 ? 166.300 149.164 189.058 1.00 22.85  ? 444 ALA A CB  1 
ATOM   3273  N  N   . VAL A 1 445 ? 163.682 151.311 188.263 1.00 23.60  ? 445 VAL A N   1 
ATOM   3274  C  CA  . VAL A 1 445 ? 163.113 152.585 188.677 1.00 23.60  ? 445 VAL A CA  1 
ATOM   3275  C  C   . VAL A 1 445 ? 163.344 152.789 190.166 1.00 23.60  ? 445 VAL A C   1 
ATOM   3276  O  O   . VAL A 1 445 ? 163.045 151.914 190.989 1.00 23.60  ? 445 VAL A O   1 
ATOM   3277  C  CB  . VAL A 1 445 ? 161.616 152.640 188.338 1.00 23.60  ? 445 VAL A CB  1 
ATOM   3278  C  CG1 . VAL A 1 445 ? 160.975 153.836 188.996 1.00 23.60  ? 445 VAL A CG1 1 
ATOM   3279  C  CG2 . VAL A 1 445 ? 161.427 152.706 186.841 1.00 23.60  ? 445 VAL A CG2 1 
ATOM   3280  N  N   . HIS A 1 446 ? 163.874 153.954 190.520 1.00 27.23  ? 446 HIS A N   1 
ATOM   3281  C  CA  . HIS A 1 446 ? 164.158 154.267 191.915 1.00 27.23  ? 446 HIS A CA  1 
ATOM   3282  C  C   . HIS A 1 446 ? 163.965 155.760 192.112 1.00 27.23  ? 446 HIS A C   1 
ATOM   3283  O  O   . HIS A 1 446 ? 164.688 156.557 191.509 1.00 27.23  ? 446 HIS A O   1 
ATOM   3284  C  CB  . HIS A 1 446 ? 165.576 153.843 192.288 1.00 27.23  ? 446 HIS A CB  1 
ATOM   3285  C  CG  . HIS A 1 446 ? 165.876 153.951 193.748 1.00 27.23  ? 446 HIS A CG  1 
ATOM   3286  N  ND1 . HIS A 1 446 ? 166.350 155.108 194.326 1.00 27.23  ? 446 HIS A ND1 1 
ATOM   3287  C  CD2 . HIS A 1 446 ? 165.768 153.047 194.748 1.00 27.23  ? 446 HIS A CD2 1 
ATOM   3288  C  CE1 . HIS A 1 446 ? 166.522 154.911 195.620 1.00 27.23  ? 446 HIS A CE1 1 
ATOM   3289  N  NE2 . HIS A 1 446 ? 166.176 153.668 195.902 1.00 27.23  ? 446 HIS A NE2 1 
ATOM   3290  N  N   . LYS A 1 447 ? 162.993 156.127 192.949 1.00 25.57  ? 447 LYS A N   1 
ATOM   3291  C  CA  . LYS A 1 447 ? 162.626 157.518 193.189 1.00 25.57  ? 447 LYS A CA  1 
ATOM   3292  C  C   . LYS A 1 447 ? 162.173 158.175 191.890 1.00 25.57  ? 447 LYS A C   1 
ATOM   3293  O  O   . LYS A 1 447 ? 161.229 157.707 191.248 1.00 25.57  ? 447 LYS A O   1 
ATOM   3294  C  CB  . LYS A 1 447 ? 163.793 158.289 193.808 1.00 25.57  ? 447 LYS A CB  1 
ATOM   3295  C  CG  . LYS A 1 447 ? 164.315 157.687 195.099 1.00 25.57  ? 447 LYS A CG  1 
ATOM   3296  C  CD  . LYS A 1 447 ? 163.289 157.759 196.213 1.00 25.57  ? 447 LYS A CD  1 
ATOM   3297  C  CE  . LYS A 1 447 ? 163.855 157.204 197.512 1.00 25.57  ? 447 LYS A CE  1 
ATOM   3298  N  NZ  . LYS A 1 447 ? 162.846 157.223 198.607 1.00 25.57  ? 447 LYS A NZ  1 
ATOM   3299  N  N   . ASP A 1 448 ? 162.838 159.261 191.499 1.00 26.15  ? 448 ASP A N   1 
ATOM   3300  C  CA  . ASP A 1 448 ? 162.579 159.920 190.228 1.00 26.15  ? 448 ASP A CA  1 
ATOM   3301  C  C   . ASP A 1 448 ? 163.511 159.454 189.119 1.00 26.15  ? 448 ASP A C   1 
ATOM   3302  O  O   . ASP A 1 448 ? 163.394 159.934 187.988 1.00 26.15  ? 448 ASP A O   1 
ATOM   3303  C  CB  . ASP A 1 448 ? 162.707 161.444 190.396 1.00 26.15  ? 448 ASP A CB  1 
ATOM   3304  C  CG  . ASP A 1 448 ? 162.210 162.219 189.188 1.00 26.15  ? 448 ASP A CG  1 
ATOM   3305  O  OD1 . ASP A 1 448 ? 160.979 162.311 189.002 1.00 26.15  ? 448 ASP A OD1 1 
ATOM   3306  O  OD2 . ASP A 1 448 ? 163.050 162.739 188.426 1.00 26.15  ? 448 ASP A OD2 1 
ATOM   3307  N  N   . LEU A 1 449 ? 164.401 158.512 189.406 1.00 22.57  ? 449 LEU A N   1 
ATOM   3308  C  CA  . LEU A 1 449 ? 165.529 158.175 188.554 1.00 22.57  ? 449 LEU A CA  1 
ATOM   3309  C  C   . LEU A 1 449 ? 165.385 156.761 188.006 1.00 22.57  ? 449 LEU A C   1 
ATOM   3310  O  O   . LEU A 1 449 ? 164.630 155.940 188.532 1.00 22.57  ? 449 LEU A O   1 
ATOM   3311  C  CB  . LEU A 1 449 ? 166.827 158.298 189.351 1.00 22.57  ? 449 LEU A CB  1 
ATOM   3312  C  CG  . LEU A 1 449 ? 167.045 159.690 189.942 1.00 22.57  ? 449 LEU A CG  1 
ATOM   3313  C  CD1 . LEU A 1 449 ? 168.197 159.697 190.917 1.00 22.57  ? 449 LEU A CD1 1 
ATOM   3314  C  CD2 . LEU A 1 449 ? 167.273 160.696 188.843 1.00 22.57  ? 449 LEU A CD2 1 
ATOM   3315  N  N   . VAL A 1 450 ? 166.128 156.483 186.940 1.00 24.22  ? 450 VAL A N   1 
ATOM   3316  C  CA  . VAL A 1 450 ? 166.156 155.162 186.321 1.00 24.22  ? 450 VAL A CA  1 
ATOM   3317  C  C   . VAL A 1 450 ? 167.597 154.676 186.339 1.00 24.22  ? 450 VAL A C   1 
ATOM   3318  O  O   . VAL A 1 450 ? 168.445 155.197 185.605 1.00 24.22  ? 450 VAL A O   1 
ATOM   3319  C  CB  . VAL A 1 450 ? 165.597 155.186 184.892 1.00 24.22  ? 450 VAL A CB  1 
ATOM   3320  C  CG1 . VAL A 1 450 ? 165.745 153.823 184.248 1.00 24.22  ? 450 VAL A CG1 1 
ATOM   3321  C  CG2 . VAL A 1 450 ? 164.143 155.605 184.902 1.00 24.22  ? 450 VAL A CG2 1 
ATOM   3322  N  N   . PHE A 1 451 ? 167.881 153.676 187.169 1.00 23.43  ? 451 PHE A N   1 
ATOM   3323  C  CA  . PHE A 1 451 ? 169.226 153.125 187.284 1.00 23.43  ? 451 PHE A CA  1 
ATOM   3324  C  C   . PHE A 1 451 ? 169.423 152.025 186.248 1.00 23.43  ? 451 PHE A C   1 
ATOM   3325  O  O   . PHE A 1 451 ? 168.888 150.921 186.393 1.00 23.43  ? 451 PHE A O   1 
ATOM   3326  C  CB  . PHE A 1 451 ? 169.472 152.600 188.695 1.00 23.43  ? 451 PHE A CB  1 
ATOM   3327  C  CG  . PHE A 1 451 ? 169.645 153.680 189.721 1.00 23.43  ? 451 PHE A CG  1 
ATOM   3328  C  CD1 . PHE A 1 451 ? 170.884 154.250 189.937 1.00 23.43  ? 451 PHE A CD1 1 
ATOM   3329  C  CD2 . PHE A 1 451 ? 168.570 154.141 190.452 1.00 23.43  ? 451 PHE A CD2 1 
ATOM   3330  C  CE1 . PHE A 1 451 ? 171.053 155.241 190.877 1.00 23.43  ? 451 PHE A CE1 1 
ATOM   3331  C  CE2 . PHE A 1 451 ? 168.732 155.139 191.392 1.00 23.43  ? 451 PHE A CE2 1 
ATOM   3332  C  CZ  . PHE A 1 451 ? 169.975 155.688 191.604 1.00 23.43  ? 451 PHE A CZ  1 
ATOM   3333  N  N   . ILE A 1 452 ? 170.195 152.331 185.210 1.00 30.91  ? 452 ILE A N   1 
ATOM   3334  C  CA  . ILE A 1 452 ? 170.455 151.433 184.093 1.00 30.91  ? 452 ILE A CA  1 
ATOM   3335  C  C   . ILE A 1 452 ? 171.810 150.780 184.321 1.00 30.91  ? 452 ILE A C   1 
ATOM   3336  O  O   . ILE A 1 452 ? 172.730 151.425 184.836 1.00 30.91  ? 452 ILE A O   1 
ATOM   3337  C  CB  . ILE A 1 452 ? 170.454 152.192 182.754 1.00 30.91  ? 452 ILE A CB  1 
ATOM   3338  C  CG1 . ILE A 1 452 ? 169.166 152.985 182.580 1.00 30.91  ? 452 ILE A CG1 1 
ATOM   3339  C  CG2 . ILE A 1 452 ? 170.583 151.229 181.595 1.00 30.91  ? 452 ILE A CG2 1 
ATOM   3340  C  CD1 . ILE A 1 452 ? 169.236 153.994 181.454 1.00 30.91  ? 452 ILE A CD1 1 
ATOM   3341  N  N   . VAL A 1 453 ? 171.945 149.518 183.915 1.00 34.07  ? 453 VAL A N   1 
ATOM   3342  C  CA  . VAL A 1 453 ? 173.213 148.806 184.009 1.00 34.07  ? 453 VAL A CA  1 
ATOM   3343  C  C   . VAL A 1 453 ? 173.300 147.817 182.852 1.00 34.07  ? 453 VAL A C   1 
ATOM   3344  O  O   . VAL A 1 453 ? 172.269 147.359 182.349 1.00 34.07  ? 453 VAL A O   1 
ATOM   3345  C  CB  . VAL A 1 453 ? 173.361 148.091 185.365 1.00 34.07  ? 453 VAL A CB  1 
ATOM   3346  C  CG1 . VAL A 1 453 ? 172.407 146.917 185.471 1.00 34.07  ? 453 VAL A CG1 1 
ATOM   3347  C  CG2 . VAL A 1 453 ? 174.785 147.660 185.563 1.00 34.07  ? 453 VAL A CG2 1 
ATOM   3348  N  N   . ALA A 1 454 ? 174.518 147.500 182.419 1.00 49.68  ? 454 ALA A N   1 
ATOM   3349  C  CA  . ALA A 1 454 ? 174.713 146.637 181.261 1.00 49.68  ? 454 ALA A CA  1 
ATOM   3350  C  C   . ALA A 1 454 ? 176.017 145.840 181.374 1.00 49.68  ? 454 ALA A C   1 
ATOM   3351  O  O   . ALA A 1 454 ? 176.256 145.126 182.355 1.00 49.68  ? 454 ALA A O   1 
ATOM   3352  C  CB  . ALA A 1 454 ? 174.673 147.463 179.975 1.00 49.68  ? 454 ALA A CB  1 
ATOM   3353  N  N   . GLU A 1 455 ? 176.874 145.982 180.361 1.00 60.79  ? 455 GLU A N   1 
ATOM   3354  C  CA  . GLU A 1 455 ? 177.888 144.973 180.066 1.00 60.79  ? 455 GLU A CA  1 
ATOM   3355  C  C   . GLU A 1 455 ? 179.142 145.140 180.920 1.00 60.79  ? 455 GLU A C   1 
ATOM   3356  O  O   . GLU A 1 455 ? 180.214 144.646 180.549 1.00 60.79  ? 455 GLU A O   1 
ATOM   3357  C  CB  . GLU A 1 455 ? 178.259 145.004 178.582 1.00 60.79  ? 455 GLU A CB  1 
ATOM   3358  C  CG  . GLU A 1 455 ? 178.999 146.258 178.122 1.00 60.79  ? 455 GLU A CG  1 
ATOM   3359  C  CD  . GLU A 1 455 ? 178.065 147.315 177.576 1.00 60.79  ? 455 GLU A CD  1 
ATOM   3360  O  OE1 . GLU A 1 455 ? 176.840 147.161 177.738 1.00 60.79  ? 455 GLU A OE1 1 
ATOM   3361  O  OE2 . GLU A 1 455 ? 178.552 148.308 177.001 1.00 60.79  ? 455 GLU A OE2 1 
ATOM   3362  N  N   . GLY A 1 456 ? 179.025 145.823 182.056 1.00 59.96  ? 456 GLY A N   1 
ATOM   3363  C  CA  . GLY A 1 456 ? 180.121 145.791 183.006 1.00 59.96  ? 456 GLY A CA  1 
ATOM   3364  C  C   . GLY A 1 456 ? 180.820 147.102 183.301 1.00 59.96  ? 456 GLY A C   1 
ATOM   3365  O  O   . GLY A 1 456 ? 180.975 147.952 182.419 1.00 59.96  ? 456 GLY A O   1 
ATOM   3366  N  N   . ASP A 1 457 ? 181.268 147.251 184.546 1.00 67.08  ? 457 ASP A N   1 
ATOM   3367  C  CA  . ASP A 1 457 ? 181.980 148.433 185.036 1.00 67.08  ? 457 ASP A CA  1 
ATOM   3368  C  C   . ASP A 1 457 ? 181.247 149.710 184.633 1.00 67.08  ? 457 ASP A C   1 
ATOM   3369  O  O   . ASP A 1 457 ? 181.824 150.671 184.123 1.00 67.08  ? 457 ASP A O   1 
ATOM   3370  C  CB  . ASP A 1 457 ? 183.430 148.438 184.552 1.00 67.08  ? 457 ASP A CB  1 
ATOM   3371  C  CG  . ASP A 1 457 ? 184.272 149.499 185.240 1.00 67.08  ? 457 ASP A CG  1 
ATOM   3372  O  OD1 . ASP A 1 457 ? 184.607 149.311 186.430 1.00 67.08  ? 457 ASP A OD1 1 
ATOM   3373  O  OD2 . ASP A 1 457 ? 184.603 150.514 184.591 1.00 67.08  ? 457 ASP A OD2 1 
ATOM   3374  N  N   . SER A 1 458 ? 179.942 149.704 184.887 1.00 53.27  ? 458 SER A N   1 
ATOM   3375  C  CA  . SER A 1 458 ? 179.079 150.803 184.475 1.00 53.27  ? 458 SER A CA  1 
ATOM   3376  C  C   . SER A 1 458 ? 177.795 150.750 185.282 1.00 53.27  ? 458 SER A C   1 
ATOM   3377  O  O   . SER A 1 458 ? 177.285 149.662 185.563 1.00 53.27  ? 458 SER A O   1 
ATOM   3378  C  CB  . SER A 1 458 ? 178.774 150.718 182.979 1.00 53.27  ? 458 SER A CB  1 
ATOM   3379  O  OG  . SER A 1 458 ? 178.018 149.557 182.684 1.00 53.27  ? 458 SER A OG  1 
ATOM   3380  N  N   . LEU A 1 459 ? 177.277 151.920 185.650 1.00 36.11  ? 459 LEU A N   1 
ATOM   3381  C  CA  . LEU A 1 459 ? 175.975 152.036 186.307 1.00 36.11  ? 459 LEU A CA  1 
ATOM   3382  C  C   . LEU A 1 459 ? 175.491 153.466 186.097 1.00 36.11  ? 459 LEU A C   1 
ATOM   3383  O  O   . LEU A 1 459 ? 175.917 154.381 186.806 1.00 36.11  ? 459 LEU A O   1 
ATOM   3384  C  CB  . LEU A 1 459 ? 176.052 151.694 187.787 1.00 36.11  ? 459 LEU A CB  1 
ATOM   3385  C  CG  . LEU A 1 459 ? 174.697 151.798 188.487 1.00 36.11  ? 459 LEU A CG  1 
ATOM   3386  C  CD1 . LEU A 1 459 ? 173.725 150.780 187.935 1.00 36.11  ? 459 LEU A CD1 1 
ATOM   3387  C  CD2 . LEU A 1 459 ? 174.839 151.627 189.973 1.00 36.11  ? 459 LEU A CD2 1 
ATOM   3388  N  N   . VAL A 1 460 ? 174.602 153.653 185.131 1.00 24.34  ? 460 VAL A N   1 
ATOM   3389  C  CA  . VAL A 1 460 ? 174.134 154.977 184.744 1.00 24.34  ? 460 VAL A CA  1 
ATOM   3390  C  C   . VAL A 1 460 ? 172.872 155.299 185.530 1.00 24.34  ? 460 VAL A C   1 
ATOM   3391  O  O   . VAL A 1 460 ? 172.074 154.405 185.827 1.00 24.34  ? 460 VAL A O   1 
ATOM   3392  C  CB  . VAL A 1 460 ? 173.894 155.048 183.228 1.00 24.34  ? 460 VAL A CB  1 
ATOM   3393  C  CG1 . VAL A 1 460 ? 173.259 156.357 182.848 1.00 24.34  ? 460 VAL A CG1 1 
ATOM   3394  C  CG2 . VAL A 1 460 ? 175.212 154.889 182.505 1.00 24.34  ? 460 VAL A CG2 1 
ATOM   3395  N  N   . CYS A 1 461 ? 172.704 156.565 185.891 1.00 26.39  ? 461 CYS A N   1 
ATOM   3396  C  CA  . CYS A 1 461 ? 171.540 157.033 186.638 1.00 26.39  ? 461 CYS A CA  1 
ATOM   3397  C  C   . CYS A 1 461 ? 170.812 158.063 185.780 1.00 26.39  ? 461 CYS A C   1 
ATOM   3398  O  O   . CYS A 1 461 ? 171.035 159.267 185.905 1.00 26.39  ? 461 CYS A O   1 
ATOM   3399  C  CB  . CYS A 1 461 ? 171.958 157.612 187.974 1.00 26.39  ? 461 CYS A CB  1 
ATOM   3400  S  SG  . CYS A 1 461 ? 170.583 158.174 188.969 1.00 26.39  ? 461 CYS A SG  1 
ATOM   3401  N  N   . TYR A 1 462 ? 169.929 157.580 184.913 1.00 25.14  ? 462 TYR A N   1 
ATOM   3402  C  CA  . TYR A 1 462 ? 169.221 158.440 183.976 1.00 25.14  ? 462 TYR A CA  1 
ATOM   3403  C  C   . TYR A 1 462 ? 168.118 159.232 184.665 1.00 25.14  ? 462 TYR A C   1 
ATOM   3404  O  O   . TYR A 1 462 ? 167.286 158.675 185.388 1.00 25.14  ? 462 TYR A O   1 
ATOM   3405  C  CB  . TYR A 1 462 ? 168.650 157.600 182.833 1.00 25.14  ? 462 TYR A CB  1 
ATOM   3406  C  CG  . TYR A 1 462 ? 167.724 158.340 181.895 1.00 25.14  ? 462 TYR A CG  1 
ATOM   3407  C  CD1 . TYR A 1 462 ? 168.182 159.387 181.114 1.00 25.14  ? 462 TYR A CD1 1 
ATOM   3408  C  CD2 . TYR A 1 462 ? 166.401 157.950 181.749 1.00 25.14  ? 462 TYR A CD2 1 
ATOM   3409  C  CE1 . TYR A 1 462 ? 167.345 160.050 180.244 1.00 25.14  ? 462 TYR A CE1 1 
ATOM   3410  C  CE2 . TYR A 1 462 ? 165.559 158.606 180.880 1.00 25.14  ? 462 TYR A CE2 1 
ATOM   3411  C  CZ  . TYR A 1 462 ? 166.038 159.656 180.132 1.00 25.14  ? 462 TYR A CZ  1 
ATOM   3412  O  OH  . TYR A 1 462 ? 165.205 160.315 179.263 1.00 25.14  ? 462 TYR A OH  1 
ATOM   3413  N  N   . ASN A 1 463 ? 168.128 160.545 184.442 1.00 24.62  ? 463 ASN A N   1 
ATOM   3414  C  CA  . ASN A 1 463 ? 167.083 161.440 184.942 1.00 24.62  ? 463 ASN A CA  1 
ATOM   3415  C  C   . ASN A 1 463 ? 166.313 161.997 183.755 1.00 24.62  ? 463 ASN A C   1 
ATOM   3416  O  O   . ASN A 1 463 ? 166.840 162.847 183.015 1.00 24.62  ? 463 ASN A O   1 
ATOM   3417  C  CB  . ASN A 1 463 ? 167.682 162.571 185.773 1.00 24.62  ? 463 ASN A CB  1 
ATOM   3418  C  CG  . ASN A 1 463 ? 166.630 163.367 186.521 1.00 24.62  ? 463 ASN A CG  1 
ATOM   3419  O  OD1 . ASN A 1 463 ? 165.437 163.102 186.404 1.00 24.62  ? 463 ASN A OD1 1 
ATOM   3420  N  ND2 . ASN A 1 463 ? 167.071 164.346 187.299 1.00 24.62  ? 463 ASN A ND2 1 
ATOM   3421  N  N   . PRO A 1 464 ? 165.071 161.561 183.527 1.00 25.76  ? 464 PRO A N   1 
ATOM   3422  C  CA  . PRO A 1 464 ? 164.366 161.970 182.303 1.00 25.76  ? 464 PRO A CA  1 
ATOM   3423  C  C   . PRO A 1 464 ? 163.820 163.384 182.340 1.00 25.76  ? 464 PRO A C   1 
ATOM   3424  O  O   . PRO A 1 464 ? 163.625 163.972 181.270 1.00 25.76  ? 464 PRO A O   1 
ATOM   3425  C  CB  . PRO A 1 464 ? 163.231 160.948 182.202 1.00 25.76  ? 464 PRO A CB  1 
ATOM   3426  C  CG  . PRO A 1 464 ? 162.978 160.561 183.605 1.00 25.76  ? 464 PRO A CG  1 
ATOM   3427  C  CD  . PRO A 1 464 ? 164.299 160.578 184.304 1.00 25.76  ? 464 PRO A CD  1 
ATOM   3428  N  N   . LEU A 1 465 ? 163.552 163.945 183.521 1.00 30.40  ? 465 LEU A N   1 
ATOM   3429  C  CA  . LEU A 1 465 ? 162.974 165.284 183.584 1.00 30.40  ? 465 LEU A CA  1 
ATOM   3430  C  C   . LEU A 1 465 ? 163.926 166.338 183.039 1.00 30.40  ? 465 LEU A C   1 
ATOM   3431  O  O   . LEU A 1 465 ? 163.520 167.173 182.224 1.00 30.40  ? 465 LEU A O   1 
ATOM   3432  C  CB  . LEU A 1 465 ? 162.577 165.629 185.019 1.00 30.40  ? 465 LEU A CB  1 
ATOM   3433  C  CG  . LEU A 1 465 ? 161.182 165.209 185.493 1.00 30.40  ? 465 LEU A CG  1 
ATOM   3434  C  CD1 . LEU A 1 465 ? 160.113 165.909 184.668 1.00 30.40  ? 465 LEU A CD1 1 
ATOM   3435  C  CD2 . LEU A 1 465 ? 160.994 163.700 185.454 1.00 30.40  ? 465 LEU A CD2 1 
ATOM   3436  N  N   . LEU A 1 466 ? 165.188 166.320 183.468 1.00 32.54  ? 466 LEU A N   1 
ATOM   3437  C  CA  . LEU A 1 466 ? 166.165 167.278 182.973 1.00 32.54  ? 466 LEU A CA  1 
ATOM   3438  C  C   . LEU A 1 466 ? 167.163 166.652 182.005 1.00 32.54  ? 466 LEU A C   1 
ATOM   3439  O  O   . LEU A 1 466 ? 168.170 167.289 181.678 1.00 32.54  ? 466 LEU A O   1 
ATOM   3440  C  CB  . LEU A 1 466 ? 166.885 167.966 184.143 1.00 32.54  ? 466 LEU A CB  1 
ATOM   3441  C  CG  . LEU A 1 466 ? 167.656 167.185 185.205 1.00 32.54  ? 466 LEU A CG  1 
ATOM   3442  C  CD1 . LEU A 1 466 ? 169.081 166.957 184.773 1.00 32.54  ? 466 LEU A CD1 1 
ATOM   3443  C  CD2 . LEU A 1 466 ? 167.618 167.936 186.524 1.00 32.54  ? 466 LEU A CD2 1 
ATOM   3444  N  N   . ASP A 1 467 ? 166.906 165.427 181.540 1.00 35.19  ? 467 ASP A N   1 
ATOM   3445  C  CA  . ASP A 1 467 ? 167.577 164.833 180.381 1.00 35.19  ? 467 ASP A CA  1 
ATOM   3446  C  C   . ASP A 1 467 ? 169.096 164.786 180.573 1.00 35.19  ? 467 ASP A C   1 
ATOM   3447  O  O   . ASP A 1 467 ? 169.856 165.502 179.919 1.00 35.19  ? 467 ASP A O   1 
ATOM   3448  C  CB  . ASP A 1 467 ? 167.223 165.603 179.103 1.00 35.19  ? 467 ASP A CB  1 
ATOM   3449  C  CG  . ASP A 1 467 ? 165.770 165.450 178.710 1.00 35.19  ? 467 ASP A CG  1 
ATOM   3450  O  OD1 . ASP A 1 467 ? 165.185 164.384 178.990 1.00 35.19  ? 467 ASP A OD1 1 
ATOM   3451  O  OD2 . ASP A 1 467 ? 165.208 166.400 178.125 1.00 35.19  ? 467 ASP A OD2 1 
ATOM   3452  N  N   . SER A 1 468 ? 169.526 163.909 181.478 1.00 30.11  ? 468 SER A N   1 
ATOM   3453  C  CA  . SER A 1 468 ? 170.956 163.745 181.691 1.00 30.11  ? 468 SER A CA  1 
ATOM   3454  C  C   . SER A 1 468 ? 171.243 162.418 182.375 1.00 30.11  ? 468 SER A C   1 
ATOM   3455  O  O   . SER A 1 468 ? 170.354 161.765 182.933 1.00 30.11  ? 468 SER A O   1 
ATOM   3456  C  CB  . SER A 1 468 ? 171.546 164.890 182.517 1.00 30.11  ? 468 SER A CB  1 
ATOM   3457  O  OG  . SER A 1 468 ? 171.089 164.830 183.851 1.00 30.11  ? 468 SER A OG  1 
ATOM   3458  N  N   . PHE A 1 469 ? 172.522 162.052 182.337 1.00 30.59  ? 469 PHE A N   1 
ATOM   3459  C  CA  . PHE A 1 469 ? 173.036 160.785 182.828 1.00 30.59  ? 469 PHE A CA  1 
ATOM   3460  C  C   . PHE A 1 469 ? 174.151 161.060 183.827 1.00 30.59  ? 469 PHE A C   1 
ATOM   3461  O  O   . PHE A 1 469 ? 174.897 162.032 183.679 1.00 30.59  ? 469 PHE A O   1 
ATOM   3462  C  CB  . PHE A 1 469 ? 173.587 159.947 181.673 1.00 30.59  ? 469 PHE A CB  1 
ATOM   3463  C  CG  . PHE A 1 469 ? 172.574 159.622 180.614 1.00 30.59  ? 469 PHE A CG  1 
ATOM   3464  C  CD1 . PHE A 1 469 ? 171.748 158.528 180.738 1.00 30.59  ? 469 PHE A CD1 1 
ATOM   3465  C  CD2 . PHE A 1 469 ? 172.448 160.421 179.493 1.00 30.59  ? 469 PHE A CD2 1 
ATOM   3466  C  CE1 . PHE A 1 469 ? 170.829 158.228 179.763 1.00 30.59  ? 469 PHE A CE1 1 
ATOM   3467  C  CE2 . PHE A 1 469 ? 171.520 160.130 178.519 1.00 30.59  ? 469 PHE A CE2 1 
ATOM   3468  C  CZ  . PHE A 1 469 ? 170.710 159.031 178.655 1.00 30.59  ? 469 PHE A CZ  1 
ATOM   3469  N  N   . THR A 1 470 ? 174.267 160.206 184.841 1.00 29.95  ? 470 THR A N   1 
ATOM   3470  C  CA  . THR A 1 470 ? 175.364 160.269 185.796 1.00 29.95  ? 470 THR A CA  1 
ATOM   3471  C  C   . THR A 1 470 ? 175.852 158.859 186.091 1.00 29.95  ? 470 THR A C   1 
ATOM   3472  O  O   . THR A 1 470 ? 175.107 158.022 186.605 1.00 29.95  ? 470 THR A O   1 
ATOM   3473  C  CB  . THR A 1 470 ? 174.962 160.954 187.113 1.00 29.95  ? 470 THR A CB  1 
ATOM   3474  O  OG1 . THR A 1 470 ? 173.883 160.236 187.721 1.00 29.95  ? 470 THR A OG1 1 
ATOM   3475  C  CG2 . THR A 1 470 ? 174.545 162.396 186.875 1.00 29.95  ? 470 THR A CG2 1 
ATOM   3476  N  N   . ARG A 1 471 ? 177.115 158.606 185.765 1.00 43.71  ? 471 ARG A N   1 
ATOM   3477  C  CA  . ARG A 1 471 ? 177.707 157.281 185.873 1.00 43.71  ? 471 ARG A CA  1 
ATOM   3478  C  C   . ARG A 1 471 ? 178.324 157.084 187.249 1.00 43.71  ? 471 ARG A C   1 
ATOM   3479  O  O   . ARG A 1 471 ? 178.887 158.017 187.829 1.00 43.71  ? 471 ARG A O   1 
ATOM   3480  C  CB  . ARG A 1 471 ? 178.771 157.071 184.795 1.00 43.71  ? 471 ARG A CB  1 
ATOM   3481  C  CG  . ARG A 1 471 ? 178.220 157.010 183.382 1.00 43.71  ? 471 ARG A CG  1 
ATOM   3482  C  CD  . ARG A 1 471 ? 179.342 156.904 182.367 1.00 43.71  ? 471 ARG A CD  1 
ATOM   3483  N  NE  . ARG A 1 471 ? 180.103 155.670 182.525 1.00 43.71  ? 471 ARG A NE  1 
ATOM   3484  C  CZ  . ARG A 1 471 ? 179.792 154.520 181.938 1.00 43.71  ? 471 ARG A CZ  1 
ATOM   3485  N  NH1 . ARG A 1 471 ? 178.731 154.443 181.148 1.00 43.71  ? 471 ARG A NH1 1 
ATOM   3486  N  NH2 . ARG A 1 471 ? 180.543 153.448 182.140 1.00 43.71  ? 471 ARG A NH2 1 
ATOM   3487  N  N   . LEU A 1 472 ? 178.220 155.861 187.761 1.00 48.29  ? 472 LEU A N   1 
ATOM   3488  C  CA  . LEU A 1 472 ? 178.850 155.463 189.011 1.00 48.29  ? 472 LEU A CA  1 
ATOM   3489  C  C   . LEU A 1 472 ? 180.040 154.562 188.714 1.00 48.29  ? 472 LEU A C   1 
ATOM   3490  O  O   . LEU A 1 472 ? 180.469 154.443 187.562 1.00 48.29  ? 472 LEU A O   1 
ATOM   3491  C  CB  . LEU A 1 472 ? 177.867 154.728 189.933 1.00 48.29  ? 472 LEU A CB  1 
ATOM   3492  C  CG  . LEU A 1 472 ? 176.856 155.537 190.749 1.00 48.29  ? 472 LEU A CG  1 
ATOM   3493  C  CD1 . LEU A 1 472 ? 175.739 156.085 189.874 1.00 48.29  ? 472 LEU A CD1 1 
ATOM   3494  C  CD2 . LEU A 1 472 ? 176.293 154.684 191.872 1.00 48.29  ? 472 LEU A CD2 1 
ATOM   3495  N  N   . CYS A 1 473 ? 180.570 153.933 189.759 1.00 64.42  ? 473 CYS A N   1 
ATOM   3496  C  CA  . CYS A 1 473 ? 181.650 152.970 189.597 1.00 64.42  ? 473 CYS A CA  1 
ATOM   3497  C  C   . CYS A 1 473 ? 181.409 151.752 190.484 1.00 64.42  ? 473 CYS A C   1 
ATOM   3498  O  O   . CYS A 1 473 ? 181.101 151.869 191.673 1.00 64.42  ? 473 CYS A O   1 
ATOM   3499  C  CB  . CYS A 1 473 ? 182.999 153.615 189.924 1.00 64.42  ? 473 CYS A CB  1 
ATOM   3500  S  SG  . CYS A 1 473 ? 183.197 154.191 191.629 1.00 64.42  ? 473 CYS A SG  1 
ATOM   3501  N  N   . LEU A 1 474 ? 181.549 150.572 189.893 1.00 65.26  ? 474 LEU A N   1 
ATOM   3502  C  CA  . LEU A 1 474 ? 181.174 149.348 190.577 1.00 65.26  ? 474 LEU A CA  1 
ATOM   3503  C  C   . LEU A 1 474 ? 182.373 148.429 190.750 1.00 65.26  ? 474 LEU A C   1 
ATOM   3504  O  O   . LEU A 1 474 ? 183.348 148.523 189.998 1.00 65.26  ? 474 LEU A O   1 
ATOM   3505  C  CB  . LEU A 1 474 ? 180.069 148.613 189.808 1.00 65.26  ? 474 LEU A CB  1 
ATOM   3506  C  CG  . LEU A 1 474 ? 178.751 149.381 189.817 1.00 65.26  ? 474 LEU A CG  1 
ATOM   3507  C  CD1 . LEU A 1 474 ? 177.705 148.638 189.027 1.00 65.26  ? 474 LEU A CD1 1 
ATOM   3508  C  CD2 . LEU A 1 474 ? 178.300 149.623 191.248 1.00 65.26  ? 474 LEU A CD2 1 
ATOM   3509  N  N   . PRO A 1 475 ? 182.331 147.535 191.743 1.00 69.98  ? 475 PRO A N   1 
ATOM   3510  C  CA  . PRO A 1 475 ? 183.432 146.579 191.911 1.00 69.98  ? 475 PRO A CA  1 
ATOM   3511  C  C   . PRO A 1 475 ? 183.404 145.490 190.854 1.00 69.98  ? 475 PRO A C   1 
ATOM   3512  O  O   . PRO A 1 475 ? 182.367 145.245 190.229 1.00 69.98  ? 475 PRO A O   1 
ATOM   3513  C  CB  . PRO A 1 475 ? 183.189 146.009 193.313 1.00 69.98  ? 475 PRO A CB  1 
ATOM   3514  C  CG  . PRO A 1 475 ? 181.724 146.133 193.510 1.00 69.98  ? 475 PRO A CG  1 
ATOM   3515  C  CD  . PRO A 1 475 ? 181.320 147.401 192.808 1.00 69.98  ? 475 PRO A CD  1 
ATOM   3516  N  N   . GLU A 1 476 ? 184.540 144.832 190.650 1.00 79.71  ? 476 GLU A N   1 
ATOM   3517  C  CA  . GLU A 1 476 ? 184.645 143.756 189.675 1.00 79.71  ? 476 GLU A CA  1 
ATOM   3518  C  C   . GLU A 1 476 ? 185.857 142.885 189.981 1.00 79.71  ? 476 GLU A C   1 
ATOM   3519  O  O   . GLU A 1 476 ? 186.754 143.292 190.720 1.00 79.71  ? 476 GLU A O   1 
ATOM   3520  C  CB  . GLU A 1 476 ? 184.736 144.324 188.256 1.00 79.71  ? 476 GLU A CB  1 
ATOM   3521  C  CG  . GLU A 1 476 ? 184.600 143.289 187.153 1.00 79.71  ? 476 GLU A CG  1 
ATOM   3522  C  CD  . GLU A 1 476 ? 185.917 142.627 186.812 1.00 79.71  ? 476 GLU A CD  1 
ATOM   3523  O  OE1 . GLU A 1 476 ? 186.969 143.276 186.991 1.00 79.71  ? 476 GLU A OE1 1 
ATOM   3524  O  OE2 . GLU A 1 476 ? 185.901 141.462 186.364 1.00 79.71  ? 476 GLU A OE2 1 
ATOM   3525  N  N   . SER A 1 483 ? 180.629 140.200 182.117 1.00 76.18  ? 483 SER A N   1 
ATOM   3526  C  CA  . SER A 1 483 ? 179.827 139.554 183.151 1.00 76.18  ? 483 SER A CA  1 
ATOM   3527  C  C   . SER A 1 483 ? 178.599 140.389 183.485 1.00 76.18  ? 483 SER A C   1 
ATOM   3528  O  O   . SER A 1 483 ? 178.638 141.233 184.374 1.00 76.18  ? 483 SER A O   1 
ATOM   3529  C  CB  . SER A 1 483 ? 180.660 139.318 184.413 1.00 76.18  ? 483 SER A CB  1 
ATOM   3530  O  OG  . SER A 1 483 ? 181.023 140.544 185.020 1.00 76.18  ? 483 SER A OG  1 
ATOM   3531  N  N   . LEU A 1 484 ? 177.512 140.144 182.759 1.00 69.19  ? 484 LEU A N   1 
ATOM   3532  C  CA  . LEU A 1 484 ? 176.268 140.871 182.977 1.00 69.19  ? 484 LEU A CA  1 
ATOM   3533  C  C   . LEU A 1 484 ? 175.786 140.695 184.411 1.00 69.19  ? 484 LEU A C   1 
ATOM   3534  O  O   . LEU A 1 484 ? 176.014 139.657 185.031 1.00 69.19  ? 484 LEU A O   1 
ATOM   3535  C  CB  . LEU A 1 484 ? 175.201 140.369 182.005 1.00 69.19  ? 484 LEU A CB  1 
ATOM   3536  C  CG  . LEU A 1 484 ? 173.796 140.980 182.004 1.00 69.19  ? 484 LEU A CG  1 
ATOM   3537  C  CD1 . LEU A 1 484 ? 173.823 142.455 181.624 1.00 69.19  ? 484 LEU A CD1 1 
ATOM   3538  C  CD2 . LEU A 1 484 ? 172.890 140.194 181.061 1.00 69.19  ? 484 LEU A CD2 1 
ATOM   3539  N  N   . TRP A 1 485 ? 175.114 141.712 184.945 1.00 62.77  ? 485 TRP A N   1 
ATOM   3540  C  CA  . TRP A 1 485 ? 174.489 141.602 186.255 1.00 62.77  ? 485 TRP A CA  1 
ATOM   3541  C  C   . TRP A 1 485 ? 173.215 142.432 186.294 1.00 62.77  ? 485 TRP A C   1 
ATOM   3542  O  O   . TRP A 1 485 ? 173.116 143.469 185.633 1.00 62.77  ? 485 TRP A O   1 
ATOM   3543  C  CB  . TRP A 1 485 ? 175.433 142.030 187.387 1.00 62.77  ? 485 TRP A CB  1 
ATOM   3544  C  CG  . TRP A 1 485 ? 175.934 143.422 187.322 1.00 62.77  ? 485 TRP A CG  1 
ATOM   3545  C  CD1 . TRP A 1 485 ? 175.257 144.538 187.668 1.00 62.77  ? 485 TRP A CD1 1 
ATOM   3546  C  CD2 . TRP A 1 485 ? 177.253 143.847 186.969 1.00 62.77  ? 485 TRP A CD2 1 
ATOM   3547  N  NE1 . TRP A 1 485 ? 176.050 145.643 187.522 1.00 62.77  ? 485 TRP A NE1 1 
ATOM   3548  C  CE2 . TRP A 1 485 ? 177.283 145.246 187.085 1.00 62.77  ? 485 TRP A CE2 1 
ATOM   3549  C  CE3 . TRP A 1 485 ? 178.404 143.183 186.549 1.00 62.77  ? 485 TRP A CE3 1 
ATOM   3550  C  CZ2 . TRP A 1 485 ? 178.415 145.994 186.798 1.00 62.77  ? 485 TRP A CZ2 1 
ATOM   3551  C  CZ3 . TRP A 1 485 ? 179.530 143.924 186.262 1.00 62.77  ? 485 TRP A CZ3 1 
ATOM   3552  C  CH2 . TRP A 1 485 ? 179.530 145.316 186.393 1.00 62.77  ? 485 TRP A CH2 1 
ATOM   3553  N  N   . LYS A 1 486 ? 172.245 141.966 187.074 1.00 44.96  ? 486 LYS A N   1 
ATOM   3554  C  CA  . LYS A 1 486 ? 170.926 142.571 187.164 1.00 44.96  ? 486 LYS A CA  1 
ATOM   3555  C  C   . LYS A 1 486 ? 170.868 143.572 188.311 1.00 44.96  ? 486 LYS A C   1 
ATOM   3556  O  O   . LYS A 1 486 ? 171.770 143.661 189.146 1.00 44.96  ? 486 LYS A O   1 
ATOM   3557  C  CB  . LYS A 1 486 ? 169.849 141.497 187.348 1.00 44.96  ? 486 LYS A CB  1 
ATOM   3558  C  CG  . LYS A 1 486 ? 169.406 140.807 186.069 1.00 44.96  ? 486 LYS A CG  1 
ATOM   3559  C  CD  . LYS A 1 486 ? 170.416 139.789 185.581 1.00 44.96  ? 486 LYS A CD  1 
ATOM   3560  C  CE  . LYS A 1 486 ? 169.888 139.083 184.348 1.00 44.96  ? 486 LYS A CE  1 
ATOM   3561  N  NZ  . LYS A 1 486 ? 170.862 138.128 183.761 1.00 44.96  ? 486 LYS A NZ  1 
ATOM   3562  N  N   . ILE A 1 487 ? 169.769 144.321 188.350 1.00 34.88  ? 487 ILE A N   1 
ATOM   3563  C  CA  . ILE A 1 487 ? 169.568 145.392 189.316 1.00 34.88  ? 487 ILE A CA  1 
ATOM   3564  C  C   . ILE A 1 487 ? 168.131 145.328 189.817 1.00 34.88  ? 487 ILE A C   1 
ATOM   3565  O  O   . ILE A 1 487 ? 167.224 144.931 189.077 1.00 34.88  ? 487 ILE A O   1 
ATOM   3566  C  CB  . ILE A 1 487 ? 169.890 146.770 188.696 1.00 34.88  ? 487 ILE A CB  1 
ATOM   3567  C  CG1 . ILE A 1 487 ? 169.923 147.862 189.759 1.00 34.88  ? 487 ILE A CG1 1 
ATOM   3568  C  CG2 . ILE A 1 487 ? 168.903 147.125 187.602 1.00 34.88  ? 487 ILE A CG2 1 
ATOM   3569  C  CD1 . ILE A 1 487 ? 170.540 149.144 189.269 1.00 34.88  ? 487 ILE A CD1 1 
ATOM   3570  N  N   . ALA A 1 488 ? 167.926 145.700 191.079 1.00 35.45  ? 488 ALA A N   1 
ATOM   3571  C  CA  . ALA A 1 488 ? 166.613 145.634 191.703 1.00 35.45  ? 488 ALA A CA  1 
ATOM   3572  C  C   . ALA A 1 488 ? 166.512 146.679 192.804 1.00 35.45  ? 488 ALA A C   1 
ATOM   3573  O  O   . ALA A 1 488 ? 167.498 147.018 193.465 1.00 35.45  ? 488 ALA A O   1 
ATOM   3574  C  CB  . ALA A 1 488 ? 166.330 144.243 192.277 1.00 35.45  ? 488 ALA A CB  1 
ATOM   3575  N  N   . SER A 1 489 ? 165.292 147.176 193.005 1.00 44.49  ? 489 SER A N   1 
ATOM   3576  C  CA  . SER A 1 489 ? 165.019 148.221 193.985 1.00 44.49  ? 489 SER A CA  1 
ATOM   3577  C  C   . SER A 1 489 ? 163.979 147.720 194.974 1.00 44.49  ? 489 SER A C   1 
ATOM   3578  O  O   . SER A 1 489 ? 162.799 147.612 194.631 1.00 44.49  ? 489 SER A O   1 
ATOM   3579  C  CB  . SER A 1 489 ? 164.529 149.498 193.299 1.00 44.49  ? 489 SER A CB  1 
ATOM   3580  O  OG  . SER A 1 489 ? 164.193 150.487 194.253 1.00 44.49  ? 489 SER A OG  1 
ATOM   3581  N  N   . CYS A 1 490 ? 164.412 147.428 196.199 1.00 58.75  ? 490 CYS A N   1 
ATOM   3582  C  CA  . CYS A 1 490 ? 163.516 146.918 197.226 1.00 58.75  ? 490 CYS A CA  1 
ATOM   3583  C  C   . CYS A 1 490 ? 162.659 148.058 197.754 1.00 58.75  ? 490 CYS A C   1 
ATOM   3584  O  O   . CYS A 1 490 ? 161.486 148.182 197.392 1.00 58.75  ? 490 CYS A O   1 
ATOM   3585  C  CB  . CYS A 1 490 ? 164.290 146.272 198.380 1.00 58.75  ? 490 CYS A CB  1 
ATOM   3586  S  SG  . CYS A 1 490 ? 165.294 147.435 199.331 1.00 58.75  ? 490 CYS A SG  1 
ATOM   3587  N  N   . ASN A 1 491 ? 163.254 148.881 198.616 1.00 64.37  ? 491 ASN A N   1 
ATOM   3588  C  CA  . ASN A 1 491 ? 162.570 150.023 199.218 1.00 64.37  ? 491 ASN A CA  1 
ATOM   3589  C  C   . ASN A 1 491 ? 163.435 151.279 199.139 1.00 64.37  ? 491 ASN A C   1 
ATOM   3590  O  O   . ASN A 1 491 ? 163.096 152.262 198.477 1.00 64.37  ? 491 ASN A O   1 
ATOM   3591  C  CB  . ASN A 1 491 ? 162.174 149.723 200.665 1.00 64.37  ? 491 ASN A CB  1 
ATOM   3592  C  CG  . ASN A 1 491 ? 161.183 148.584 200.775 1.00 64.37  ? 491 ASN A CG  1 
ATOM   3593  O  OD1 . ASN A 1 491 ? 161.489 147.533 201.336 1.00 64.37  ? 491 ASN A OD1 1 
ATOM   3594  N  ND2 . ASN A 1 491 ? 159.987 148.785 200.233 1.00 64.37  ? 491 ASN A ND2 1 
ATOM   3595  N  N   . GLY A 1 492 ? 164.573 151.236 199.828 1.00 57.31  ? 492 GLY A N   1 
ATOM   3596  C  CA  . GLY A 1 492 ? 165.455 152.384 199.887 1.00 57.31  ? 492 GLY A CA  1 
ATOM   3597  C  C   . GLY A 1 492 ? 166.899 152.069 199.557 1.00 57.31  ? 492 GLY A C   1 
ATOM   3598  O  O   . GLY A 1 492 ? 167.796 152.867 199.844 1.00 57.31  ? 492 GLY A O   1 
ATOM   3599  N  N   . SER A 1 493 ? 167.138 150.905 198.960 1.00 48.96  ? 493 SER A N   1 
ATOM   3600  C  CA  . SER A 1 493 ? 168.481 150.533 198.549 1.00 48.96  ? 493 SER A CA  1 
ATOM   3601  C  C   . SER A 1 493 ? 168.434 149.818 197.201 1.00 48.96  ? 493 SER A C   1 
ATOM   3602  O  O   . SER A 1 493 ? 167.409 149.269 196.793 1.00 48.96  ? 493 SER A O   1 
ATOM   3603  C  CB  . SER A 1 493 ? 169.137 149.647 199.606 1.00 48.96  ? 493 SER A CB  1 
ATOM   3604  O  OG  . SER A 1 493 ? 169.315 150.354 200.821 1.00 48.96  ? 493 SER A OG  1 
ATOM   3605  N  N   . ILE A 1 494 ? 169.564 149.831 196.499 1.00 36.62  ? 494 ILE A N   1 
ATOM   3606  C  CA  . ILE A 1 494 ? 169.648 149.269 195.157 1.00 36.62  ? 494 ILE A CA  1 
ATOM   3607  C  C   . ILE A 1 494 ? 170.432 147.967 195.221 1.00 36.62  ? 494 ILE A C   1 
ATOM   3608  O  O   . ILE A 1 494 ? 171.666 147.976 195.148 1.00 36.62  ? 494 ILE A O   1 
ATOM   3609  C  CB  . ILE A 1 494 ? 170.304 150.250 194.173 1.00 36.62  ? 494 ILE A CB  1 
ATOM   3610  C  CG1 . ILE A 1 494 ? 169.493 151.534 194.078 1.00 36.62  ? 494 ILE A CG1 1 
ATOM   3611  C  CG2 . ILE A 1 494 ? 170.396 149.638 192.799 1.00 36.62  ? 494 ILE A CG2 1 
ATOM   3612  C  CD1 . ILE A 1 494 ? 170.212 152.612 193.324 1.00 36.62  ? 494 ILE A CD1 1 
ATOM   3613  N  N   . TYR A 1 495 ? 169.723 146.850 195.347 1.00 44.39  ? 495 TYR A N   1 
ATOM   3614  C  CA  . TYR A 1 495 ? 170.353 145.536 195.375 1.00 44.39  ? 495 TYR A CA  1 
ATOM   3615  C  C   . TYR A 1 495 ? 170.754 145.151 193.960 1.00 44.39  ? 495 TYR A C   1 
ATOM   3616  O  O   . TYR A 1 495 ? 169.897 145.020 193.081 1.00 44.39  ? 495 TYR A O   1 
ATOM   3617  C  CB  . TYR A 1 495 ? 169.427 144.481 195.977 1.00 44.39  ? 495 TYR A CB  1 
ATOM   3618  C  CG  . TYR A 1 495 ? 169.233 144.626 197.464 1.00 44.39  ? 495 TYR A CG  1 
ATOM   3619  C  CD1 . TYR A 1 495 ? 170.200 144.186 198.353 1.00 44.39  ? 495 TYR A CD1 1 
ATOM   3620  C  CD2 . TYR A 1 495 ? 168.083 145.196 197.980 1.00 44.39  ? 495 TYR A CD2 1 
ATOM   3621  C  CE1 . TYR A 1 495 ? 170.028 144.317 199.715 1.00 44.39  ? 495 TYR A CE1 1 
ATOM   3622  C  CE2 . TYR A 1 495 ? 167.904 145.329 199.339 1.00 44.39  ? 495 TYR A CE2 1 
ATOM   3623  C  CZ  . TYR A 1 495 ? 168.877 144.889 200.203 1.00 44.39  ? 495 TYR A CZ  1 
ATOM   3624  O  OH  . TYR A 1 495 ? 168.698 145.022 201.560 1.00 44.39  ? 495 TYR A OH  1 
ATOM   3625  N  N   . VAL A 1 496 ? 172.052 144.972 193.744 1.00 46.81  ? 496 VAL A N   1 
ATOM   3626  C  CA  . VAL A 1 496 ? 172.594 144.573 192.453 1.00 46.81  ? 496 VAL A CA  1 
ATOM   3627  C  C   . VAL A 1 496 ? 173.041 143.118 192.552 1.00 46.81  ? 496 VAL A C   1 
ATOM   3628  O  O   . VAL A 1 496 ? 173.725 142.727 193.509 1.00 46.81  ? 496 VAL A O   1 
ATOM   3629  C  CB  . VAL A 1 496 ? 173.734 145.509 192.017 1.00 46.81  ? 496 VAL A CB  1 
ATOM   3630  C  CG1 . VAL A 1 496 ? 174.830 145.545 193.046 1.00 46.81  ? 496 VAL A CG1 1 
ATOM   3631  C  CG2 . VAL A 1 496 ? 174.291 145.077 190.699 1.00 46.81  ? 496 VAL A CG2 1 
ATOM   3632  N  N   . PHE A 1 497 ? 172.632 142.310 191.569 1.00 48.80  ? 497 PHE A N   1 
ATOM   3633  C  CA  . PHE A 1 497 ? 172.753 140.852 191.607 1.00 48.80  ? 497 PHE A CA  1 
ATOM   3634  C  C   . PHE A 1 497 ? 173.704 140.391 190.508 1.00 48.80  ? 497 PHE A C   1 
ATOM   3635  O  O   . PHE A 1 497 ? 173.519 140.729 189.339 1.00 48.80  ? 497 PHE A O   1 
ATOM   3636  C  CB  . PHE A 1 497 ? 171.388 140.192 191.424 1.00 48.80  ? 497 PHE A CB  1 
ATOM   3637  C  CG  . PHE A 1 497 ? 170.432 140.427 192.557 1.00 48.80  ? 497 PHE A CG  1 
ATOM   3638  C  CD1 . PHE A 1 497 ? 170.479 139.647 193.698 1.00 48.80  ? 497 PHE A CD1 1 
ATOM   3639  C  CD2 . PHE A 1 497 ? 169.475 141.421 192.474 1.00 48.80  ? 497 PHE A CD2 1 
ATOM   3640  C  CE1 . PHE A 1 497 ? 169.592 139.860 194.734 1.00 48.80  ? 497 PHE A CE1 1 
ATOM   3641  C  CE2 . PHE A 1 497 ? 168.589 141.638 193.509 1.00 48.80  ? 497 PHE A CE2 1 
ATOM   3642  C  CZ  . PHE A 1 497 ? 168.649 140.857 194.640 1.00 48.80  ? 497 PHE A CZ  1 
ATOM   3643  N  N   . ARG A 1 498 ? 174.698 139.589 190.880 1.00 69.58  ? 498 ARG A N   1 
ATOM   3644  C  CA  . ARG A 1 498 ? 175.563 138.952 189.895 1.00 69.58  ? 498 ARG A CA  1 
ATOM   3645  C  C   . ARG A 1 498 ? 174.937 137.641 189.435 1.00 69.58  ? 498 ARG A C   1 
ATOM   3646  O  O   . ARG A 1 498 ? 174.724 136.729 190.239 1.00 69.58  ? 498 ARG A O   1 
ATOM   3647  C  CB  . ARG A 1 498 ? 176.946 138.716 190.500 1.00 69.58  ? 498 ARG A CB  1 
ATOM   3648  C  CG  . ARG A 1 498 ? 177.991 138.043 189.614 1.00 69.58  ? 498 ARG A CG  1 
ATOM   3649  C  CD  . ARG A 1 498 ? 178.560 138.990 188.569 1.00 69.58  ? 498 ARG A CD  1 
ATOM   3650  N  NE  . ARG A 1 498 ? 177.865 138.875 187.290 1.00 69.58  ? 498 ARG A NE  1 
ATOM   3651  C  CZ  . ARG A 1 498 ? 178.164 137.956 186.376 1.00 69.58  ? 498 ARG A CZ  1 
ATOM   3652  N  NH1 . ARG A 1 498 ? 179.149 137.098 186.602 1.00 69.58  ? 498 ARG A NH1 1 
ATOM   3653  N  NH2 . ARG A 1 498 ? 177.493 137.901 185.234 1.00 69.58  ? 498 ARG A NH2 1 
ATOM   3654  N  N   . ASP A 1 499 ? 174.635 137.546 188.137 1.00 75.10  ? 499 ASP A N   1 
ATOM   3655  C  CA  . ASP A 1 499 ? 173.843 136.447 187.598 1.00 75.10  ? 499 ASP A CA  1 
ATOM   3656  C  C   . ASP A 1 499 ? 174.689 135.227 187.245 1.00 75.10  ? 499 ASP A C   1 
ATOM   3657  O  O   . ASP A 1 499 ? 174.279 134.403 186.421 1.00 75.10  ? 499 ASP A O   1 
ATOM   3658  C  CB  . ASP A 1 499 ? 173.038 136.914 186.382 1.00 75.10  ? 499 ASP A CB  1 
ATOM   3659  C  CG  . ASP A 1 499 ? 173.911 137.293 185.195 1.00 75.10  ? 499 ASP A CG  1 
ATOM   3660  O  OD1 . ASP A 1 499 ? 175.152 137.182 185.285 1.00 75.10  ? 499 ASP A OD1 1 
ATOM   3661  O  OD2 . ASP A 1 499 ? 173.345 137.714 184.162 1.00 75.10  ? 499 ASP A OD2 1 
ATOM   3662  N  N   . ARG A 1 500 ? 175.871 135.100 187.849 1.00 84.32  ? 500 ARG A N   1 
ATOM   3663  C  CA  . ARG A 1 500 ? 176.786 134.007 187.552 1.00 84.32  ? 500 ARG A CA  1 
ATOM   3664  C  C   . ARG A 1 500 ? 177.682 133.807 188.777 1.00 84.32  ? 500 ARG A C   1 
ATOM   3665  O  O   . ARG A 1 500 ? 178.271 134.737 189.326 1.00 84.32  ? 500 ARG A O   1 
ATOM   3666  C  CB  . ARG A 1 500 ? 177.603 134.288 186.289 1.00 84.32  ? 500 ARG A CB  1 
ATOM   3667  C  CG  . ARG A 1 500 ? 178.603 133.207 185.933 1.00 84.32  ? 500 ARG A CG  1 
ATOM   3668  C  CD  . ARG A 1 500 ? 177.908 131.931 185.494 1.00 84.32  ? 500 ARG A CD  1 
ATOM   3669  N  NE  . ARG A 1 500 ? 178.870 130.891 185.142 1.00 84.32  ? 500 ARG A NE  1 
ATOM   3670  C  CZ  . ARG A 1 500 ? 179.388 130.734 183.928 1.00 84.32  ? 500 ARG A CZ  1 
ATOM   3671  N  NH1 . ARG A 1 500 ? 179.037 131.551 182.945 1.00 84.32  ? 500 ARG A NH1 1 
ATOM   3672  N  NH2 . ARG A 1 500 ? 180.259 129.761 183.696 1.00 84.32  ? 500 ARG A NH2 1 
ATOM   3673  N  N   . TYR A 1 501 ? 177.787 132.560 189.220 1.00 90.58  ? 501 TYR A N   1 
ATOM   3674  C  CA  . TYR A 1 501 ? 178.548 132.249 190.418 1.00 90.58  ? 501 TYR A CA  1 
ATOM   3675  C  C   . TYR A 1 501 ? 179.621 131.211 190.123 1.00 90.58  ? 501 TYR A C   1 
ATOM   3676  O  O   . TYR A 1 501 ? 179.446 130.323 189.283 1.00 90.58  ? 501 TYR A O   1 
ATOM   3677  C  CB  . TYR A 1 501 ? 177.623 131.729 191.519 1.00 90.58  ? 501 TYR A CB  1 
ATOM   3678  C  CG  . TYR A 1 501 ? 176.611 132.740 192.008 1.00 90.58  ? 501 TYR A CG  1 
ATOM   3679  C  CD1 . TYR A 1 501 ? 176.960 133.709 192.940 1.00 90.58  ? 501 TYR A CD1 1 
ATOM   3680  C  CD2 . TYR A 1 501 ? 175.306 132.725 191.536 1.00 90.58  ? 501 TYR A CD2 1 
ATOM   3681  C  CE1 . TYR A 1 501 ? 176.036 134.634 193.389 1.00 90.58  ? 501 TYR A CE1 1 
ATOM   3682  C  CE2 . TYR A 1 501 ? 174.375 133.645 191.978 1.00 90.58  ? 501 TYR A CE2 1 
ATOM   3683  C  CZ  . TYR A 1 501 ? 174.745 134.597 192.904 1.00 90.58  ? 501 TYR A CZ  1 
ATOM   3684  O  OH  . TYR A 1 501 ? 173.818 135.512 193.345 1.00 90.58  ? 501 TYR A OH  1 
ATOM   3685  N  N   . LYS A 1 502 ? 180.744 131.334 190.822 1.00 93.99  ? 502 LYS A N   1 
ATOM   3686  C  CA  . LYS A 1 502 ? 181.772 130.294 190.827 1.00 93.99  ? 502 LYS A CA  1 
ATOM   3687  C  C   . LYS A 1 502 ? 181.594 129.395 192.051 1.00 93.99  ? 502 LYS A C   1 
ATOM   3688  O  O   . LYS A 1 502 ? 182.498 128.674 192.479 1.00 93.99  ? 502 LYS A O   1 
ATOM   3689  C  CB  . LYS A 1 502 ? 183.167 130.916 190.773 1.00 93.99  ? 502 LYS A CB  1 
ATOM   3690  C  CG  . LYS A 1 502 ? 183.669 131.527 192.077 1.00 93.99  ? 502 LYS A CG  1 
ATOM   3691  C  CD  . LYS A 1 502 ? 183.081 132.905 192.326 1.00 93.99  ? 502 LYS A CD  1 
ATOM   3692  C  CE  . LYS A 1 502 ? 183.683 133.936 191.385 1.00 93.99  ? 502 LYS A CE  1 
ATOM   3693  N  NZ  . LYS A 1 502 ? 183.113 135.294 191.605 1.00 93.99  ? 502 LYS A NZ  1 
ATOM   3694  N  N   . LYS A 1 503 ? 180.382 129.459 192.602 1.00 91.78  ? 503 LYS A N   1 
ATOM   3695  C  CA  . LYS A 1 503 ? 179.953 128.646 193.740 1.00 91.78  ? 503 LYS A CA  1 
ATOM   3696  C  C   . LYS A 1 503 ? 180.755 128.988 194.996 1.00 91.78  ? 503 LYS A C   1 
ATOM   3697  O  O   . LYS A 1 503 ? 181.870 128.512 195.214 1.00 91.78  ? 503 LYS A O   1 
ATOM   3698  C  CB  . LYS A 1 503 ? 180.043 127.153 193.410 1.00 91.78  ? 503 LYS A CB  1 
ATOM   3699  C  CG  . LYS A 1 503 ? 179.056 126.696 192.347 1.00 91.78  ? 503 LYS A CG  1 
ATOM   3700  C  CD  . LYS A 1 503 ? 179.145 125.196 192.116 1.00 91.78  ? 503 LYS A CD  1 
ATOM   3701  C  CE  . LYS A 1 503 ? 180.029 124.872 190.922 1.00 91.78  ? 503 LYS A CE  1 
ATOM   3702  N  NZ  . LYS A 1 503 ? 181.473 125.074 191.218 1.00 91.78  ? 503 LYS A NZ  1 
ATOM   3703  N  N   . GLY A 1 504 ? 180.152 129.831 195.832 1.00 87.07  ? 504 GLY A N   1 
ATOM   3704  C  CA  . GLY A 1 504 ? 180.757 130.214 197.093 1.00 87.07  ? 504 GLY A CA  1 
ATOM   3705  C  C   . GLY A 1 504 ? 181.484 131.542 197.045 1.00 87.07  ? 504 GLY A C   1 
ATOM   3706  O  O   . GLY A 1 504 ? 182.709 131.591 197.186 1.00 87.07  ? 504 GLY A O   1 
ATOM   3707  N  N   . ASP A 1 505 ? 180.737 132.632 196.850 1.00 83.88  ? 505 ASP A N   1 
ATOM   3708  C  CA  . ASP A 1 505 ? 181.328 133.962 196.768 1.00 83.88  ? 505 ASP A CA  1 
ATOM   3709  C  C   . ASP A 1 505 ? 180.383 135.015 197.338 1.00 83.88  ? 505 ASP A C   1 
ATOM   3710  O  O   . ASP A 1 505 ? 180.829 136.082 197.776 1.00 83.88  ? 505 ASP A O   1 
ATOM   3711  C  CB  . ASP A 1 505 ? 181.693 134.305 195.320 1.00 83.88  ? 505 ASP A CB  1 
ATOM   3712  C  CG  . ASP A 1 505 ? 182.639 135.491 195.213 1.00 83.88  ? 505 ASP A CG  1 
ATOM   3713  O  OD1 . ASP A 1 505 ? 183.042 136.043 196.257 1.00 83.88  ? 505 ASP A OD1 1 
ATOM   3714  O  OD2 . ASP A 1 505 ? 182.983 135.869 194.074 1.00 83.88  ? 505 ASP A OD2 1 
ATOM   3715  N  N   . ALA A 1 506 ? 179.080 134.725 197.346 1.00 78.62  ? 506 ALA A N   1 
ATOM   3716  C  CA  . ALA A 1 506 ? 178.058 135.652 197.819 1.00 78.62  ? 506 ALA A CA  1 
ATOM   3717  C  C   . ALA A 1 506 ? 178.138 136.975 197.069 1.00 78.62  ? 506 ALA A C   1 
ATOM   3718  O  O   . ALA A 1 506 ? 178.467 138.011 197.656 1.00 78.62  ? 506 ALA A O   1 
ATOM   3719  C  CB  . ALA A 1 506 ? 178.183 135.880 199.328 1.00 78.62  ? 506 ALA A CB  1 
ATOM   3720  N  N   . ASN A 1 507 ? 177.845 136.947 195.771 1.00 73.83  ? 507 ASN A N   1 
ATOM   3721  C  CA  . ASN A 1 507 ? 177.878 138.138 194.925 1.00 73.83  ? 507 ASN A CA  1 
ATOM   3722  C  C   . ASN A 1 507 ? 176.506 138.787 194.804 1.00 73.83  ? 507 ASN A C   1 
ATOM   3723  O  O   . ASN A 1 507 ? 175.936 138.872 193.713 1.00 73.83  ? 507 ASN A O   1 
ATOM   3724  C  CB  . ASN A 1 507 ? 178.435 137.794 193.548 1.00 73.83  ? 507 ASN A CB  1 
ATOM   3725  C  CG  . ASN A 1 507 ? 179.923 137.506 193.576 1.00 73.83  ? 507 ASN A CG  1 
ATOM   3726  O  OD1 . ASN A 1 507 ? 180.688 138.190 194.256 1.00 73.83  ? 507 ASN A OD1 1 
ATOM   3727  N  ND2 . ASN A 1 507 ? 180.342 136.492 192.830 1.00 73.83  ? 507 ASN A ND2 1 
ATOM   3728  N  N   . THR A 1 508 ? 175.956 139.247 195.923 1.00 61.86  ? 508 THR A N   1 
ATOM   3729  C  CA  . THR A 1 508 ? 174.686 139.965 195.970 1.00 61.86  ? 508 THR A CA  1 
ATOM   3730  C  C   . THR A 1 508 ? 174.963 141.287 196.678 1.00 61.86  ? 508 THR A C   1 
ATOM   3731  O  O   . THR A 1 508 ? 174.824 141.395 197.898 1.00 61.86  ? 508 THR A O   1 
ATOM   3732  C  CB  . THR A 1 508 ? 173.615 139.148 196.687 1.00 61.86  ? 508 THR A CB  1 
ATOM   3733  O  OG1 . THR A 1 508 ? 173.393 137.923 195.976 1.00 61.86  ? 508 THR A OG1 1 
ATOM   3734  C  CG2 . THR A 1 508 ? 172.315 139.923 196.765 1.00 61.86  ? 508 THR A CG2 1 
ATOM   3735  N  N   . TYR A 1 509 ? 175.371 142.290 195.911 1.00 57.32  ? 509 TYR A N   1 
ATOM   3736  C  CA  . TYR A 1 509 ? 175.809 143.542 196.503 1.00 57.32  ? 509 TYR A CA  1 
ATOM   3737  C  C   . TYR A 1 509 ? 174.615 144.427 196.840 1.00 57.32  ? 509 TYR A C   1 
ATOM   3738  O  O   . TYR A 1 509 ? 173.606 144.451 196.134 1.00 57.32  ? 509 TYR A O   1 
ATOM   3739  C  CB  . TYR A 1 509 ? 176.753 144.289 195.561 1.00 57.32  ? 509 TYR A CB  1 
ATOM   3740  C  CG  . TYR A 1 509 ? 178.067 143.598 195.290 1.00 57.32  ? 509 TYR A CG  1 
ATOM   3741  C  CD1 . TYR A 1 509 ? 179.127 143.704 196.177 1.00 57.32  ? 509 TYR A CD1 1 
ATOM   3742  C  CD2 . TYR A 1 509 ? 178.251 142.847 194.138 1.00 57.32  ? 509 TYR A CD2 1 
ATOM   3743  C  CE1 . TYR A 1 509 ? 180.333 143.080 195.926 1.00 57.32  ? 509 TYR A CE1 1 
ATOM   3744  C  CE2 . TYR A 1 509 ? 179.452 142.218 193.880 1.00 57.32  ? 509 TYR A CE2 1 
ATOM   3745  C  CZ  . TYR A 1 509 ? 180.490 142.336 194.778 1.00 57.32  ? 509 TYR A CZ  1 
ATOM   3746  O  OH  . TYR A 1 509 ? 181.688 141.710 194.525 1.00 57.32  ? 509 TYR A OH  1 
ATOM   3747  N  N   . LYS A 1 510 ? 174.743 145.155 197.944 1.00 49.69  ? 510 LYS A N   1 
ATOM   3748  C  CA  . LYS A 1 510 ? 173.778 146.173 198.337 1.00 49.69  ? 510 LYS A CA  1 
ATOM   3749  C  C   . LYS A 1 510 ? 174.370 147.537 198.032 1.00 49.69  ? 510 LYS A C   1 
ATOM   3750  O  O   . LYS A 1 510 ? 175.393 147.916 198.611 1.00 49.69  ? 510 LYS A O   1 
ATOM   3751  C  CB  . LYS A 1 510 ? 173.429 146.076 199.817 1.00 49.69  ? 510 LYS A CB  1 
ATOM   3752  C  CG  . LYS A 1 510 ? 172.419 147.114 200.263 1.00 49.69  ? 510 LYS A CG  1 
ATOM   3753  C  CD  . LYS A 1 510 ? 172.108 146.982 201.739 1.00 49.69  ? 510 LYS A CD  1 
ATOM   3754  C  CE  . LYS A 1 510 ? 171.043 147.971 202.159 1.00 49.69  ? 510 LYS A CE  1 
ATOM   3755  N  NZ  . LYS A 1 510 ? 171.534 149.370 202.062 1.00 49.69  ? 510 LYS A NZ  1 
ATOM   3756  N  N   . LEU A 1 511 ? 173.722 148.274 197.144 1.00 38.04  ? 511 LEU A N   1 
ATOM   3757  C  CA  . LEU A 1 511 ? 174.248 149.533 196.647 1.00 38.04  ? 511 LEU A CA  1 
ATOM   3758  C  C   . LEU A 1 511 ? 173.516 150.692 197.302 1.00 38.04  ? 511 LEU A C   1 
ATOM   3759  O  O   . LEU A 1 511 ? 172.284 150.784 197.222 1.00 38.04  ? 511 LEU A O   1 
ATOM   3760  C  CB  . LEU A 1 511 ? 174.124 149.608 195.126 1.00 38.04  ? 511 LEU A CB  1 
ATOM   3761  C  CG  . LEU A 1 511 ? 174.853 150.756 194.435 1.00 38.04  ? 511 LEU A CG  1 
ATOM   3762  C  CD1 . LEU A 1 511 ? 175.349 150.262 193.113 1.00 38.04  ? 511 LEU A CD1 1 
ATOM   3763  C  CD2 . LEU A 1 511 ? 173.938 151.944 194.222 1.00 38.04  ? 511 LEU A CD2 1 
ATOM   3764  N  N   . ASP A 1 512 ? 174.284 151.558 197.965 1.00 38.28  ? 512 ASP A N   1 
ATOM   3765  C  CA  . ASP A 1 512 ? 173.821 152.852 198.450 1.00 38.28  ? 512 ASP A CA  1 
ATOM   3766  C  C   . ASP A 1 512 ? 174.362 153.916 197.507 1.00 38.28  ? 512 ASP A C   1 
ATOM   3767  O  O   . ASP A 1 512 ? 175.571 154.197 197.518 1.00 38.28  ? 512 ASP A O   1 
ATOM   3768  C  CB  . ASP A 1 512 ? 174.297 153.105 199.883 1.00 38.28  ? 512 ASP A CB  1 
ATOM   3769  C  CG  . ASP A 1 512 ? 173.641 154.318 200.510 1.00 38.28  ? 512 ASP A CG  1 
ATOM   3770  O  OD1 . ASP A 1 512 ? 172.827 154.975 199.832 1.00 38.28  ? 512 ASP A OD1 1 
ATOM   3771  O  OD2 . ASP A 1 512 ? 173.939 154.617 201.685 1.00 38.28  ? 512 ASP A OD2 1 
ATOM   3772  N  N   . PRO A 1 513 ? 173.521 154.527 196.670 1.00 34.98  ? 513 PRO A N   1 
ATOM   3773  C  CA  . PRO A 1 513 ? 174.045 155.421 195.627 1.00 34.98  ? 513 PRO A CA  1 
ATOM   3774  C  C   . PRO A 1 513 ? 174.365 156.819 196.115 1.00 34.98  ? 513 PRO A C   1 
ATOM   3775  O  O   . PRO A 1 513 ? 174.951 157.596 195.352 1.00 34.98  ? 513 PRO A O   1 
ATOM   3776  C  CB  . PRO A 1 513 ? 172.917 155.438 194.591 1.00 34.98  ? 513 PRO A CB  1 
ATOM   3777  C  CG  . PRO A 1 513 ? 171.697 155.187 195.393 1.00 34.98  ? 513 PRO A CG  1 
ATOM   3778  C  CD  . PRO A 1 513 ? 172.080 154.277 196.513 1.00 34.98  ? 513 PRO A CD  1 
ATOM   3779  N  N   . ALA A 1 514 ? 174.000 157.173 197.348 1.00 36.84  ? 514 ALA A N   1 
ATOM   3780  C  CA  . ALA A 1 514 ? 174.352 158.492 197.863 1.00 36.84  ? 514 ALA A CA  1 
ATOM   3781  C  C   . ALA A 1 514 ? 175.862 158.644 197.993 1.00 36.84  ? 514 ALA A C   1 
ATOM   3782  O  O   . ALA A 1 514 ? 176.429 159.657 197.570 1.00 36.84  ? 514 ALA A O   1 
ATOM   3783  C  CB  . ALA A 1 514 ? 173.669 158.733 199.208 1.00 36.84  ? 514 ALA A CB  1 
ATOM   3784  N  N   . THR A 1 515 ? 176.529 157.642 198.564 1.00 42.11  ? 515 THR A N   1 
ATOM   3785  C  CA  . THR A 1 515 ? 177.979 157.645 198.708 1.00 42.11  ? 515 THR A CA  1 
ATOM   3786  C  C   . THR A 1 515 ? 178.652 156.598 197.830 1.00 42.11  ? 515 THR A C   1 
ATOM   3787  O  O   . THR A 1 515 ? 179.850 156.341 198.001 1.00 42.11  ? 515 THR A O   1 
ATOM   3788  C  CB  . THR A 1 515 ? 178.370 157.418 200.171 1.00 42.11  ? 515 THR A CB  1 
ATOM   3789  O  OG1 . THR A 1 515 ? 177.898 156.135 200.599 1.00 42.11  ? 515 THR A OG1 1 
ATOM   3790  C  CG2 . THR A 1 515 ? 177.763 158.492 201.056 1.00 42.11  ? 515 THR A CG2 1 
ATOM   3791  N  N   . SER A 1 516 ? 177.914 155.990 196.899 1.00 42.54  ? 516 SER A N   1 
ATOM   3792  C  CA  . SER A 1 516 ? 178.434 154.931 196.032 1.00 42.54  ? 516 SER A CA  1 
ATOM   3793  C  C   . SER A 1 516 ? 178.998 153.774 196.852 1.00 42.54  ? 516 SER A C   1 
ATOM   3794  O  O   . SER A 1 516 ? 179.975 153.131 196.464 1.00 42.54  ? 516 SER A O   1 
ATOM   3795  C  CB  . SER A 1 516 ? 179.484 155.473 195.060 1.00 42.54  ? 516 SER A CB  1 
ATOM   3796  O  OG  . SER A 1 516 ? 178.915 156.415 194.168 1.00 42.54  ? 516 SER A OG  1 
ATOM   3797  N  N   . ALA A 1 517 ? 178.371 153.501 197.996 1.00 48.91  ? 517 ALA A N   1 
ATOM   3798  C  CA  . ALA A 1 517 ? 178.835 152.475 198.924 1.00 48.91  ? 517 ALA A CA  1 
ATOM   3799  C  C   . ALA A 1 517 ? 178.238 151.134 198.511 1.00 48.91  ? 517 ALA A C   1 
ATOM   3800  O  O   . ALA A 1 517 ? 177.030 150.915 198.650 1.00 48.91  ? 517 ALA A O   1 
ATOM   3801  C  CB  . ALA A 1 517 ? 178.456 152.828 200.361 1.00 48.91  ? 517 ALA A CB  1 
ATOM   3802  N  N   . VAL A 1 518 ? 179.085 150.241 198.010 1.00 52.16  ? 518 VAL A N   1 
ATOM   3803  C  CA  . VAL A 1 518 ? 178.663 148.933 197.525 1.00 52.16  ? 518 VAL A CA  1 
ATOM   3804  C  C   . VAL A 1 518 ? 179.096 147.884 198.541 1.00 52.16  ? 518 VAL A C   1 
ATOM   3805  O  O   . VAL A 1 518 ? 180.277 147.524 198.608 1.00 52.16  ? 518 VAL A O   1 
ATOM   3806  C  CB  . VAL A 1 518 ? 179.250 148.636 196.137 1.00 52.16  ? 518 VAL A CB  1 
ATOM   3807  C  CG1 . VAL A 1 518 ? 178.870 147.238 195.687 1.00 52.16  ? 518 VAL A CG1 1 
ATOM   3808  C  CG2 . VAL A 1 518 ? 178.778 149.671 195.131 1.00 52.16  ? 518 VAL A CG2 1 
ATOM   3809  N  N   . THR A 1 519 ? 178.143 147.393 199.330 1.00 56.96  ? 519 THR A N   1 
ATOM   3810  C  CA  . THR A 1 519 ? 178.410 146.400 200.359 1.00 56.96  ? 519 THR A CA  1 
ATOM   3811  C  C   . THR A 1 519 ? 178.022 145.018 199.853 1.00 56.96  ? 519 THR A C   1 
ATOM   3812  O  O   . THR A 1 519 ? 177.531 144.857 198.732 1.00 56.96  ? 519 THR A O   1 
ATOM   3813  C  CB  . THR A 1 519 ? 177.652 146.707 201.658 1.00 56.96  ? 519 THR A CB  1 
ATOM   3814  O  OG1 . THR A 1 519 ? 176.241 146.654 201.413 1.00 56.96  ? 519 THR A OG1 1 
ATOM   3815  C  CG2 . THR A 1 519 ? 178.015 148.089 202.172 1.00 56.96  ? 519 THR A CG2 1 
ATOM   3816  N  N   . VAL A 1 520 ? 178.243 144.020 200.702 1.00 65.13  ? 520 VAL A N   1 
ATOM   3817  C  CA  . VAL A 1 520 ? 177.957 142.625 200.386 1.00 65.13  ? 520 VAL A CA  1 
ATOM   3818  C  C   . VAL A 1 520 ? 176.993 142.115 201.449 1.00 65.13  ? 520 VAL A C   1 
ATOM   3819  O  O   . VAL A 1 520 ? 177.404 141.780 202.566 1.00 65.13  ? 520 VAL A O   1 
ATOM   3820  C  CB  . VAL A 1 520 ? 179.230 141.775 200.339 1.00 65.13  ? 520 VAL A CB  1 
ATOM   3821  C  CG1 . VAL A 1 520 ? 178.887 140.321 200.051 1.00 65.13  ? 520 VAL A CG1 1 
ATOM   3822  C  CG2 . VAL A 1 520 ? 180.200 142.321 199.310 1.00 65.13  ? 520 VAL A CG2 1 
ATOM   3823  N  N   . THR A 1 521 ? 175.710 142.051 201.114 1.00 71.27  ? 521 THR A N   1 
ATOM   3824  C  CA  . THR A 1 521 ? 174.723 141.522 202.040 1.00 71.27  ? 521 THR A CA  1 
ATOM   3825  C  C   . THR A 1 521 ? 174.481 140.040 201.785 1.00 71.27  ? 521 THR A C   1 
ATOM   3826  O  O   . THR A 1 521 ? 174.856 139.488 200.748 1.00 71.27  ? 521 THR A O   1 
ATOM   3827  C  CB  . THR A 1 521 ? 173.403 142.285 201.940 1.00 71.27  ? 521 THR A CB  1 
ATOM   3828  O  OG1 . THR A 1 521 ? 172.909 142.225 200.596 1.00 71.27  ? 521 THR A OG1 1 
ATOM   3829  C  CG2 . THR A 1 521 ? 173.596 143.727 202.360 1.00 71.27  ? 521 THR A CG2 1 
ATOM   3830  N  N   . ARG A 1 522 ? 173.839 139.402 202.753 1.00 87.39  ? 522 ARG A N   1 
ATOM   3831  C  CA  . ARG A 1 522 ? 173.623 137.965 202.718 1.00 87.39  ? 522 ARG A CA  1 
ATOM   3832  C  C   . ARG A 1 522 ? 172.339 137.659 203.484 1.00 87.39  ? 522 ARG A C   1 
ATOM   3833  O  O   . ARG A 1 522 ? 171.378 138.435 203.443 1.00 87.39  ? 522 ARG A O   1 
ATOM   3834  C  CB  . ARG A 1 522 ? 174.871 137.241 203.254 1.00 87.39  ? 522 ARG A CB  1 
ATOM   3835  C  CG  . ARG A 1 522 ? 175.231 137.567 204.697 1.00 87.39  ? 522 ARG A CG  1 
ATOM   3836  C  CD  . ARG A 1 522 ? 176.523 136.878 205.094 1.00 87.39  ? 522 ARG A CD  1 
ATOM   3837  N  NE  . ARG A 1 522 ? 177.658 137.393 204.334 1.00 87.39  ? 522 ARG A NE  1 
ATOM   3838  C  CZ  . ARG A 1 522 ? 178.279 136.723 203.368 1.00 87.39  ? 522 ARG A CZ  1 
ATOM   3839  N  NH1 . ARG A 1 522 ? 177.875 135.504 203.038 1.00 87.39  ? 522 ARG A NH1 1 
ATOM   3840  N  NH2 . ARG A 1 522 ? 179.303 137.273 202.730 1.00 87.39  ? 522 ARG A NH2 1 
ATOM   3841  N  N   . GLY A 1 523 ? 172.318 136.529 204.184 1.00 92.69  ? 523 GLY A N   1 
ATOM   3842  C  CA  . GLY A 1 523 ? 171.115 136.013 204.786 1.00 92.69  ? 523 GLY A CA  1 
ATOM   3843  C  C   . GLY A 1 523 ? 170.302 135.132 203.863 1.00 92.69  ? 523 GLY A C   1 
ATOM   3844  O  O   . GLY A 1 523 ? 169.435 134.389 204.337 1.00 92.69  ? 523 GLY A O   1 
ATOM   3845  N  N   . ILE A 1 524 ? 170.560 135.204 202.559 1.00 92.72  ? 524 ILE A N   1 
ATOM   3846  C  CA  . ILE A 1 524 ? 169.940 134.315 201.586 1.00 92.72  ? 524 ILE A CA  1 
ATOM   3847  C  C   . ILE A 1 524 ? 170.457 132.899 201.804 1.00 92.72  ? 524 ILE A C   1 
ATOM   3848  O  O   . ILE A 1 524 ? 171.649 132.690 202.058 1.00 92.72  ? 524 ILE A O   1 
ATOM   3849  C  CB  . ILE A 1 524 ? 170.199 134.804 200.148 1.00 92.72  ? 524 ILE A CB  1 
ATOM   3850  C  CG1 . ILE A 1 524 ? 169.442 133.935 199.145 1.00 92.72  ? 524 ILE A CG1 1 
ATOM   3851  C  CG2 . ILE A 1 524 ? 171.694 134.848 199.843 1.00 92.72  ? 524 ILE A CG2 1 
ATOM   3852  C  CD1 . ILE A 1 524 ? 167.949 133.984 199.304 1.00 92.72  ? 524 ILE A CD1 1 
ATOM   3853  N  N   . LYS A 1 525 ? 169.560 131.920 201.727 1.00 93.99  ? 525 LYS A N   1 
ATOM   3854  C  CA  . LYS A 1 525 ? 169.921 130.526 201.968 1.00 93.99  ? 525 LYS A CA  1 
ATOM   3855  C  C   . LYS A 1 525 ? 169.386 129.694 200.808 1.00 93.99  ? 525 LYS A C   1 
ATOM   3856  O  O   . LYS A 1 525 ? 168.527 128.828 200.985 1.00 93.99  ? 525 LYS A O   1 
ATOM   3857  C  CB  . LYS A 1 525 ? 169.365 130.057 203.309 1.00 93.99  ? 525 LYS A CB  1 
ATOM   3858  C  CG  . LYS A 1 525 ? 169.847 128.684 203.758 1.00 93.99  ? 525 LYS A CG  1 
ATOM   3859  C  CD  . LYS A 1 525 ? 171.315 128.725 204.154 1.00 93.99  ? 525 LYS A CD  1 
ATOM   3860  C  CE  . LYS A 1 525 ? 171.773 127.393 204.725 1.00 93.99  ? 525 LYS A CE  1 
ATOM   3861  N  NZ  . LYS A 1 525 ? 173.226 127.400 205.056 1.00 93.99  ? 525 LYS A NZ  1 
ATOM   3862  N  N   . VAL A 1 526 ? 169.887 129.972 199.604 1.00 88.58  ? 526 VAL A N   1 
ATOM   3863  C  CA  . VAL A 1 526 ? 169.521 129.232 198.403 1.00 88.58  ? 526 VAL A CA  1 
ATOM   3864  C  C   . VAL A 1 526 ? 170.761 129.114 197.526 1.00 88.58  ? 526 VAL A C   1 
ATOM   3865  O  O   . VAL A 1 526 ? 171.664 129.953 197.566 1.00 88.58  ? 526 VAL A O   1 
ATOM   3866  C  CB  . VAL A 1 526 ? 168.363 129.901 197.628 1.00 88.58  ? 526 VAL A CB  1 
ATOM   3867  C  CG1 . VAL A 1 526 ? 168.825 131.194 196.978 1.00 88.58  ? 526 VAL A CG1 1 
ATOM   3868  C  CG2 . VAL A 1 526 ? 167.770 128.946 196.597 1.00 88.58  ? 526 VAL A CG2 1 
ATOM   3869  N  N   . LEU A 1 527 ? 170.805 128.042 196.738 1.00 86.58  ? 527 LEU A N   1 
ATOM   3870  C  CA  . LEU A 1 527 ? 171.910 127.792 195.825 1.00 86.58  ? 527 LEU A CA  1 
ATOM   3871  C  C   . LEU A 1 527 ? 171.595 128.186 194.389 1.00 86.58  ? 527 LEU A C   1 
ATOM   3872  O  O   . LEU A 1 527 ? 172.123 127.559 193.465 1.00 86.58  ? 527 LEU A O   1 
ATOM   3873  C  CB  . LEU A 1 527 ? 172.312 126.310 195.868 1.00 86.58  ? 527 LEU A CB  1 
ATOM   3874  C  CG  . LEU A 1 527 ? 173.174 125.831 197.041 1.00 86.58  ? 527 LEU A CG  1 
ATOM   3875  C  CD1 . LEU A 1 527 ? 172.377 125.754 198.338 1.00 86.58  ? 527 LEU A CD1 1 
ATOM   3876  C  CD2 . LEU A 1 527 ? 173.809 124.485 196.721 1.00 86.58  ? 527 LEU A CD2 1 
ATOM   3877  N  N   . LEU A 1 528 ? 170.759 129.204 194.184 1.00 82.15  ? 528 LEU A N   1 
ATOM   3878  C  CA  . LEU A 1 528 ? 170.348 129.591 192.841 1.00 82.15  ? 528 LEU A CA  1 
ATOM   3879  C  C   . LEU A 1 528 ? 171.550 130.025 192.012 1.00 82.15  ? 528 LEU A C   1 
ATOM   3880  O  O   . LEU A 1 528 ? 172.179 131.050 192.285 1.00 82.15  ? 528 LEU A O   1 
ATOM   3881  C  CB  . LEU A 1 528 ? 169.318 130.720 192.909 1.00 82.15  ? 528 LEU A CB  1 
ATOM   3882  C  CG  . LEU A 1 528 ? 168.726 131.174 191.574 1.00 82.15  ? 528 LEU A CG  1 
ATOM   3883  C  CD1 . LEU A 1 528 ? 167.951 130.043 190.926 1.00 82.15  ? 528 LEU A CD1 1 
ATOM   3884  C  CD2 . LEU A 1 528 ? 167.837 132.387 191.767 1.00 82.15  ? 528 LEU A CD2 1 
ATOM   3885  N  N   . THR A 1 529 ? 171.864 129.228 190.990 1.00 83.72  ? 529 THR A N   1 
ATOM   3886  C  CA  . THR A 1 529 ? 173.015 129.498 190.133 1.00 83.72  ? 529 THR A CA  1 
ATOM   3887  C  C   . THR A 1 529 ? 172.749 130.499 189.021 1.00 83.72  ? 529 THR A C   1 
ATOM   3888  O  O   . THR A 1 529 ? 172.879 131.703 189.268 1.00 83.72  ? 529 THR A O   1 
ATOM   3889  C  CB  . THR A 1 529 ? 173.529 128.198 189.505 1.00 83.72  ? 529 THR A CB  1 
ATOM   3890  O  OG1 . THR A 1 529 ? 172.498 127.615 188.699 1.00 83.72  ? 529 THR A OG1 1 
ATOM   3891  C  CG2 . THR A 1 529 ? 173.939 127.213 190.586 1.00 83.72  ? 529 THR A CG2 1 
ATOM   3892  N  N   . ASN A 1 530 ? 172.387 130.068 187.816 1.00 77.30  ? 530 ASN A N   1 
ATOM   3893  C  CA  . ASN A 1 530 ? 172.128 130.957 186.689 1.00 77.30  ? 530 ASN A CA  1 
ATOM   3894  C  C   . ASN A 1 530 ? 170.695 131.469 186.741 1.00 77.30  ? 530 ASN A C   1 
ATOM   3895  O  O   . ASN A 1 530 ? 169.749 130.801 186.318 1.00 77.30  ? 530 ASN A O   1 
ATOM   3896  C  CB  . ASN A 1 530 ? 172.404 130.241 185.369 1.00 77.30  ? 530 ASN A CB  1 
ATOM   3897  C  CG  . ASN A 1 530 ? 172.665 131.200 184.223 1.00 77.30  ? 530 ASN A CG  1 
ATOM   3898  O  OD1 . ASN A 1 530 ? 173.177 130.804 183.176 1.00 77.30  ? 530 ASN A OD1 1 
ATOM   3899  N  ND2 . ASN A 1 530 ? 172.323 132.469 184.416 1.00 77.30  ? 530 ASN A ND2 1 
ATOM   3900  N  N   . LEU A 1 531 ? 170.518 132.677 187.270 1.00 65.47  ? 531 LEU A N   1 
ATOM   3901  C  CA  . LEU A 1 531 ? 169.191 133.273 187.329 1.00 65.47  ? 531 LEU A CA  1 
ATOM   3902  C  C   . LEU A 1 531 ? 168.929 134.121 186.091 1.00 65.47  ? 531 LEU A C   1 
ATOM   3903  O  O   . LEU A 1 531 ? 169.799 134.869 185.636 1.00 65.47  ? 531 LEU A O   1 
ATOM   3904  C  CB  . LEU A 1 531 ? 169.027 134.102 188.605 1.00 65.47  ? 531 LEU A CB  1 
ATOM   3905  C  CG  . LEU A 1 531 ? 169.860 135.358 188.851 1.00 65.47  ? 531 LEU A CG  1 
ATOM   3906  C  CD1 . LEU A 1 531 ? 169.160 136.248 189.849 1.00 65.47  ? 531 LEU A CD1 1 
ATOM   3907  C  CD2 . LEU A 1 531 ? 171.207 134.964 189.407 1.00 65.47  ? 531 LEU A CD2 1 
ATOM   3908  N  N   . GLN A 1 532 ? 167.716 133.996 185.548 1.00 62.63  ? 532 GLN A N   1 
ATOM   3909  C  CA  . GLN A 1 532 ? 167.408 134.606 184.260 1.00 62.63  ? 532 GLN A CA  1 
ATOM   3910  C  C   . GLN A 1 532 ? 167.192 136.106 184.395 1.00 62.63  ? 532 GLN A C   1 
ATOM   3911  O  O   . GLN A 1 532 ? 167.732 136.894 183.610 1.00 62.63  ? 532 GLN A O   1 
ATOM   3912  C  CB  . GLN A 1 532 ? 166.176 133.942 183.648 1.00 62.63  ? 532 GLN A CB  1 
ATOM   3913  C  CG  . GLN A 1 532 ? 166.369 132.483 183.274 1.00 62.63  ? 532 GLN A CG  1 
ATOM   3914  C  CD  . GLN A 1 532 ? 165.118 131.867 182.675 1.00 62.63  ? 532 GLN A CD  1 
ATOM   3915  O  OE1 . GLN A 1 532 ? 164.079 132.518 182.576 1.00 62.63  ? 532 GLN A OE1 1 
ATOM   3916  N  NE2 . GLN A 1 532 ? 165.212 130.603 182.278 1.00 62.63  ? 532 GLN A NE2 1 
ATOM   3917  N  N   . PHE A 1 533 ? 166.396 136.521 185.378 1.00 48.46  ? 533 PHE A N   1 
ATOM   3918  C  CA  . PHE A 1 533 ? 166.097 137.933 185.562 1.00 48.46  ? 533 PHE A CA  1 
ATOM   3919  C  C   . PHE A 1 533 ? 165.527 138.160 186.953 1.00 48.46  ? 533 PHE A C   1 
ATOM   3920  O  O   . PHE A 1 533 ? 165.002 137.244 187.592 1.00 48.46  ? 533 PHE A O   1 
ATOM   3921  C  CB  . PHE A 1 533 ? 165.146 138.448 184.475 1.00 48.46  ? 533 PHE A CB  1 
ATOM   3922  C  CG  . PHE A 1 533 ? 163.913 137.613 184.299 1.00 48.46  ? 533 PHE A CG  1 
ATOM   3923  C  CD1 . PHE A 1 533 ? 163.884 136.601 183.354 1.00 48.46  ? 533 PHE A CD1 1 
ATOM   3924  C  CD2 . PHE A 1 533 ? 162.791 137.833 185.074 1.00 48.46  ? 533 PHE A CD2 1 
ATOM   3925  C  CE1 . PHE A 1 533 ? 162.763 135.828 183.181 1.00 48.46  ? 533 PHE A CE1 1 
ATOM   3926  C  CE2 . PHE A 1 533 ? 161.664 137.064 184.907 1.00 48.46  ? 533 PHE A CE2 1 
ATOM   3927  C  CZ  . PHE A 1 533 ? 161.647 136.061 183.956 1.00 48.46  ? 533 PHE A CZ  1 
ATOM   3928  N  N   . VAL A 1 534 ? 165.655 139.402 187.413 1.00 43.67  ? 534 VAL A N   1 
ATOM   3929  C  CA  . VAL A 1 534 ? 165.258 139.815 188.753 1.00 43.67  ? 534 VAL A CA  1 
ATOM   3930  C  C   . VAL A 1 534 ? 164.103 140.795 188.620 1.00 43.67  ? 534 VAL A C   1 
ATOM   3931  O  O   . VAL A 1 534 ? 164.281 141.909 188.114 1.00 43.67  ? 534 VAL A O   1 
ATOM   3932  C  CB  . VAL A 1 534 ? 166.428 140.451 189.515 1.00 43.67  ? 534 VAL A CB  1 
ATOM   3933  C  CG1 . VAL A 1 534 ? 165.966 140.956 190.864 1.00 43.67  ? 534 VAL A CG1 1 
ATOM   3934  C  CG2 . VAL A 1 534 ? 167.556 139.455 189.673 1.00 43.67  ? 534 VAL A CG2 1 
ATOM   3935  N  N   . LEU A 1 535 ? 162.924 140.384 189.075 1.00 44.71  ? 535 LEU A N   1 
ATOM   3936  C  CA  . LEU A 1 535 ? 161.722 141.203 188.995 1.00 44.71  ? 535 LEU A CA  1 
ATOM   3937  C  C   . LEU A 1 535 ? 161.571 141.987 190.291 1.00 44.71  ? 535 LEU A C   1 
ATOM   3938  O  O   . LEU A 1 535 ? 161.186 141.422 191.320 1.00 44.71  ? 535 LEU A O   1 
ATOM   3939  C  CB  . LEU A 1 535 ? 160.489 140.337 188.745 1.00 44.71  ? 535 LEU A CB  1 
ATOM   3940  C  CG  . LEU A 1 535 ? 160.477 139.581 187.419 1.00 44.71  ? 535 LEU A CG  1 
ATOM   3941  C  CD1 . LEU A 1 535 ? 159.257 138.682 187.331 1.00 44.71  ? 535 LEU A CD1 1 
ATOM   3942  C  CD2 . LEU A 1 535 ? 160.529 140.545 186.248 1.00 44.71  ? 535 LEU A CD2 1 
ATOM   3943  N  N   . ALA A 1 536 ? 161.869 143.281 190.238 1.00 44.68  ? 536 ALA A N   1 
ATOM   3944  C  CA  . ALA A 1 536 ? 161.817 144.135 191.420 1.00 44.68  ? 536 ALA A CA  1 
ATOM   3945  C  C   . ALA A 1 536 ? 160.391 144.291 191.933 1.00 44.68  ? 536 ALA A C   1 
ATOM   3946  O  O   . ALA A 1 536 ? 160.154 144.962 192.937 1.00 44.68  ? 536 ALA A O   1 
ATOM   3947  C  CB  . ALA A 1 536 ? 162.419 145.498 191.113 1.00 44.68  ? 536 ALA A CB  1 
ATOM   3948  N  N   . SER B 1 26  ? 178.784 162.545 182.924 1.00 84.05  ? 26  SER B N   1 
ATOM   3949  C  CA  . SER B 1 26  ? 179.094 163.218 184.180 1.00 84.05  ? 26  SER B CA  1 
ATOM   3950  C  C   . SER B 1 26  ? 179.827 162.276 185.127 1.00 84.05  ? 26  SER B C   1 
ATOM   3951  O  O   . SER B 1 26  ? 179.813 161.061 184.937 1.00 84.05  ? 26  SER B O   1 
ATOM   3952  C  CB  . SER B 1 26  ? 177.818 163.745 184.837 1.00 84.05  ? 26  SER B CB  1 
ATOM   3953  O  OG  . SER B 1 26  ? 177.199 164.729 184.028 1.00 84.05  ? 26  SER B OG  1 
ATOM   3954  N  N   . MET B 1 27  ? 180.470 162.840 186.147 1.00 87.78  ? 27  MET B N   1 
ATOM   3955  C  CA  . MET B 1 27  ? 181.248 162.048 187.091 1.00 87.78  ? 27  MET B CA  1 
ATOM   3956  C  C   . MET B 1 27  ? 181.223 162.601 188.508 1.00 87.78  ? 27  MET B C   1 
ATOM   3957  O  O   . MET B 1 27  ? 181.353 161.828 189.463 1.00 87.78  ? 27  MET B O   1 
ATOM   3958  C  CB  . MET B 1 27  ? 182.702 161.938 186.617 1.00 87.78  ? 27  MET B CB  1 
ATOM   3959  C  CG  . MET B 1 27  ? 183.513 163.216 186.759 1.00 87.78  ? 27  MET B CG  1 
ATOM   3960  S  SD  . MET B 1 27  ? 182.977 164.520 185.637 1.00 87.78  ? 27  MET B SD  1 
ATOM   3961  C  CE  . MET B 1 27  ? 183.499 163.843 184.063 1.00 87.78  ? 27  MET B CE  1 
ATOM   3962  N  N   . ASP B 1 28  ? 181.061 163.914 188.668 1.00 78.19  ? 28  ASP B N   1 
ATOM   3963  C  CA  . ASP B 1 28  ? 180.979 164.526 189.986 1.00 78.19  ? 28  ASP B CA  1 
ATOM   3964  C  C   . ASP B 1 28  ? 179.546 164.822 190.403 1.00 78.19  ? 28  ASP B C   1 
ATOM   3965  O  O   . ASP B 1 28  ? 179.245 164.797 191.601 1.00 78.19  ? 28  ASP B O   1 
ATOM   3966  C  CB  . ASP B 1 28  ? 181.802 165.823 190.012 1.00 78.19  ? 28  ASP B CB  1 
ATOM   3967  C  CG  . ASP B 1 28  ? 182.097 166.312 191.422 1.00 78.19  ? 28  ASP B CG  1 
ATOM   3968  O  OD1 . ASP B 1 28  ? 181.677 165.650 192.393 1.00 78.19  ? 28  ASP B OD1 1 
ATOM   3969  O  OD2 . ASP B 1 28  ? 182.759 167.363 191.557 1.00 78.19  ? 28  ASP B OD2 1 
ATOM   3970  N  N   . GLU B 1 29  ? 178.660 165.084 189.445 1.00 63.65  ? 29  GLU B N   1 
ATOM   3971  C  CA  . GLU B 1 29  ? 177.257 165.355 189.736 1.00 63.65  ? 29  GLU B CA  1 
ATOM   3972  C  C   . GLU B 1 29  ? 176.601 164.082 190.254 1.00 63.65  ? 29  GLU B C   1 
ATOM   3973  O  O   . GLU B 1 29  ? 176.456 163.103 189.515 1.00 63.65  ? 29  GLU B O   1 
ATOM   3974  C  CB  . GLU B 1 29  ? 176.547 165.868 188.488 1.00 63.65  ? 29  GLU B CB  1 
ATOM   3975  C  CG  . GLU B 1 29  ? 177.058 167.206 187.997 1.00 63.65  ? 29  GLU B CG  1 
ATOM   3976  C  CD  . GLU B 1 29  ? 176.336 167.676 186.753 1.00 63.65  ? 29  GLU B CD  1 
ATOM   3977  O  OE1 . GLU B 1 29  ? 175.501 166.911 186.228 1.00 63.65  ? 29  GLU B OE1 1 
ATOM   3978  O  OE2 . GLU B 1 29  ? 176.609 168.805 186.295 1.00 63.65  ? 29  GLU B OE2 1 
ATOM   3979  N  N   . ASN B 1 30  ? 176.209 164.091 191.524 1.00 49.06  ? 30  ASN B N   1 
ATOM   3980  C  CA  . ASN B 1 30  ? 175.520 162.974 192.154 1.00 49.06  ? 30  ASN B CA  1 
ATOM   3981  C  C   . ASN B 1 30  ? 174.132 163.447 192.560 1.00 49.06  ? 30  ASN B C   1 
ATOM   3982  O  O   . ASN B 1 30  ? 174.000 164.319 193.423 1.00 49.06  ? 30  ASN B O   1 
ATOM   3983  C  CB  . ASN B 1 30  ? 176.299 162.465 193.367 1.00 49.06  ? 30  ASN B CB  1 
ATOM   3984  C  CG  . ASN B 1 30  ? 175.798 161.125 193.861 1.00 49.06  ? 30  ASN B CG  1 
ATOM   3985  O  OD1 . ASN B 1 30  ? 174.871 160.550 193.296 1.00 49.06  ? 30  ASN B OD1 1 
ATOM   3986  N  ND2 . ASN B 1 30  ? 176.411 160.620 194.922 1.00 49.06  ? 30  ASN B ND2 1 
ATOM   3987  N  N   . TYR B 1 31  ? 173.101 162.865 191.945 1.00 41.12  ? 31  TYR B N   1 
ATOM   3988  C  CA  . TYR B 1 31  ? 171.727 163.304 192.162 1.00 41.12  ? 31  TYR B CA  1 
ATOM   3989  C  C   . TYR B 1 31  ? 171.253 163.132 193.597 1.00 41.12  ? 31  TYR B C   1 
ATOM   3990  O  O   . TYR B 1 31  ? 170.142 163.567 193.911 1.00 41.12  ? 31  TYR B O   1 
ATOM   3991  C  CB  . TYR B 1 31  ? 170.790 162.558 191.218 1.00 41.12  ? 31  TYR B CB  1 
ATOM   3992  C  CG  . TYR B 1 31  ? 170.922 163.010 189.790 1.00 41.12  ? 31  TYR B CG  1 
ATOM   3993  C  CD1 . TYR B 1 31  ? 171.481 164.237 189.487 1.00 41.12  ? 31  TYR B CD1 1 
ATOM   3994  C  CD2 . TYR B 1 31  ? 170.516 162.205 188.745 1.00 41.12  ? 31  TYR B CD2 1 
ATOM   3995  C  CE1 . TYR B 1 31  ? 171.611 164.659 188.186 1.00 41.12  ? 31  TYR B CE1 1 
ATOM   3996  C  CE2 . TYR B 1 31  ? 170.649 162.619 187.441 1.00 41.12  ? 31  TYR B CE2 1 
ATOM   3997  C  CZ  . TYR B 1 31  ? 171.195 163.846 187.168 1.00 41.12  ? 31  TYR B CZ  1 
ATOM   3998  O  OH  . TYR B 1 31  ? 171.331 164.266 185.871 1.00 41.12  ? 31  TYR B OH  1 
ATOM   3999  N  N   . PHE B 1 32  ? 172.043 162.503 194.465 1.00 41.02  ? 32  PHE B N   1 
ATOM   4000  C  CA  . PHE B 1 32  ? 171.716 162.445 195.882 1.00 41.02  ? 32  PHE B CA  1 
ATOM   4001  C  C   . PHE B 1 32  ? 172.622 163.326 196.728 1.00 41.02  ? 32  PHE B C   1 
ATOM   4002  O  O   . PHE B 1 32  ? 172.428 163.395 197.946 1.00 41.02  ? 32  PHE B O   1 
ATOM   4003  C  CB  . PHE B 1 32  ? 171.792 161.004 196.408 1.00 41.02  ? 32  PHE B CB  1 
ATOM   4004  C  CG  . PHE B 1 32  ? 170.766 160.075 195.818 1.00 41.02  ? 32  PHE B CG  1 
ATOM   4005  C  CD1 . PHE B 1 32  ? 169.783 160.536 194.974 1.00 41.02  ? 32  PHE B CD1 1 
ATOM   4006  C  CD2 . PHE B 1 32  ? 170.759 158.742 196.155 1.00 41.02  ? 32  PHE B CD2 1 
ATOM   4007  C  CE1 . PHE B 1 32  ? 168.849 159.675 194.443 1.00 41.02  ? 32  PHE B CE1 1 
ATOM   4008  C  CE2 . PHE B 1 32  ? 169.810 157.890 195.635 1.00 41.02  ? 32  PHE B CE2 1 
ATOM   4009  C  CZ  . PHE B 1 32  ? 168.859 158.359 194.779 1.00 41.02  ? 32  PHE B CZ  1 
ATOM   4010  N  N   . VAL B 1 33  ? 173.603 163.990 196.119 1.00 45.59  ? 33  VAL B N   1 
ATOM   4011  C  CA  . VAL B 1 33  ? 174.529 164.850 196.847 1.00 45.59  ? 33  VAL B CA  1 
ATOM   4012  C  C   . VAL B 1 33  ? 174.491 166.254 196.259 1.00 45.59  ? 33  VAL B C   1 
ATOM   4013  O  O   . VAL B 1 33  ? 174.080 167.205 196.931 1.00 45.59  ? 33  VAL B O   1 
ATOM   4014  C  CB  . VAL B 1 33  ? 175.957 164.279 196.821 1.00 45.59  ? 33  VAL B CB  1 
ATOM   4015  C  CG1 . VAL B 1 33  ? 176.925 165.257 197.462 1.00 45.59  ? 33  VAL B CG1 1 
ATOM   4016  C  CG2 . VAL B 1 33  ? 176.004 162.940 197.536 1.00 45.59  ? 33  VAL B CG2 1 
ATOM   4017  N  N   . ASN B 1 34  ? 174.913 166.397 195.003 1.00 46.21  ? 34  ASN B N   1 
ATOM   4018  C  CA  . ASN B 1 34  ? 174.893 167.701 194.355 1.00 46.21  ? 34  ASN B CA  1 
ATOM   4019  C  C   . ASN B 1 34  ? 174.868 167.529 192.844 1.00 46.21  ? 34  ASN B C   1 
ATOM   4020  O  O   . ASN B 1 34  ? 175.329 166.512 192.323 1.00 46.21  ? 34  ASN B O   1 
ATOM   4021  C  CB  . ASN B 1 34  ? 176.095 168.555 194.776 1.00 46.21  ? 34  ASN B CB  1 
ATOM   4022  C  CG  . ASN B 1 34  ? 177.430 167.902 194.464 1.00 46.21  ? 34  ASN B CG  1 
ATOM   4023  O  OD1 . ASN B 1 34  ? 177.494 166.826 193.877 1.00 46.21  ? 34  ASN B OD1 1 
ATOM   4024  N  ND2 . ASN B 1 34  ? 178.510 168.563 194.858 1.00 46.21  ? 34  ASN B ND2 1 
ATOM   4025  N  N   . TYR B 1 35  ? 174.331 168.531 192.152 1.00 42.21  ? 35  TYR B N   1 
ATOM   4026  C  CA  . TYR B 1 35  ? 174.287 168.531 190.696 1.00 42.21  ? 35  TYR B CA  1 
ATOM   4027  C  C   . TYR B 1 35  ? 173.863 169.914 190.227 1.00 42.21  ? 35  TYR B C   1 
ATOM   4028  O  O   . TYR B 1 35  ? 173.496 170.778 191.026 1.00 42.21  ? 35  TYR B O   1 
ATOM   4029  C  CB  . TYR B 1 35  ? 173.355 167.438 190.165 1.00 42.21  ? 35  TYR B CB  1 
ATOM   4030  C  CG  . TYR B 1 35  ? 171.907 167.600 190.552 1.00 42.21  ? 35  TYR B CG  1 
ATOM   4031  C  CD1 . TYR B 1 35  ? 171.451 167.180 191.788 1.00 42.21  ? 35  TYR B CD1 1 
ATOM   4032  C  CD2 . TYR B 1 35  ? 170.984 168.119 189.662 1.00 42.21  ? 35  TYR B CD2 1 
ATOM   4033  C  CE1 . TYR B 1 35  ? 170.130 167.312 192.141 1.00 42.21  ? 35  TYR B CE1 1 
ATOM   4034  C  CE2 . TYR B 1 35  ? 169.657 168.250 190.008 1.00 42.21  ? 35  TYR B CE2 1 
ATOM   4035  C  CZ  . TYR B 1 35  ? 169.238 167.846 191.249 1.00 42.21  ? 35  TYR B CZ  1 
ATOM   4036  O  OH  . TYR B 1 35  ? 167.920 167.969 191.606 1.00 42.21  ? 35  TYR B OH  1 
ATOM   4037  N  N   . THR B 1 36  ? 173.924 170.116 188.915 1.00 45.47  ? 36  THR B N   1 
ATOM   4038  C  CA  . THR B 1 36  ? 173.677 171.417 188.308 1.00 45.47  ? 36  THR B CA  1 
ATOM   4039  C  C   . THR B 1 36  ? 172.299 171.422 187.660 1.00 45.47  ? 36  THR B C   1 
ATOM   4040  O  O   . THR B 1 36  ? 172.121 170.870 186.570 1.00 45.47  ? 36  THR B O   1 
ATOM   4041  C  CB  . THR B 1 36  ? 174.755 171.746 187.277 1.00 45.47  ? 36  THR B CB  1 
ATOM   4042  O  OG1 . THR B 1 36  ? 176.035 171.760 187.917 1.00 45.47  ? 36  THR B OG1 1 
ATOM   4043  C  CG2 . THR B 1 36  ? 174.506 173.104 186.657 1.00 45.47  ? 36  THR B CG2 1 
ATOM   4044  N  N   . PHE B 1 37  ? 171.332 172.043 188.329 1.00 45.39  ? 37  PHE B N   1 
ATOM   4045  C  CA  . PHE B 1 37  ? 169.975 172.167 187.807 1.00 45.39  ? 37  PHE B CA  1 
ATOM   4046  C  C   . PHE B 1 37  ? 169.923 173.309 186.801 1.00 45.39  ? 37  PHE B C   1 
ATOM   4047  O  O   . PHE B 1 37  ? 170.086 174.477 187.166 1.00 45.39  ? 37  PHE B O   1 
ATOM   4048  C  CB  . PHE B 1 37  ? 168.976 172.387 188.939 1.00 45.39  ? 37  PHE B CB  1 
ATOM   4049  C  CG  . PHE B 1 37  ? 167.591 172.719 188.462 1.00 45.39  ? 37  PHE B CG  1 
ATOM   4050  C  CD1 . PHE B 1 37  ? 166.828 171.779 187.799 1.00 45.39  ? 37  PHE B CD1 1 
ATOM   4051  C  CD2 . PHE B 1 37  ? 167.043 173.966 188.700 1.00 45.39  ? 37  PHE B CD2 1 
ATOM   4052  C  CE1 . PHE B 1 37  ? 165.557 172.082 187.358 1.00 45.39  ? 37  PHE B CE1 1 
ATOM   4053  C  CE2 . PHE B 1 37  ? 165.769 174.270 188.268 1.00 45.39  ? 37  PHE B CE2 1 
ATOM   4054  C  CZ  . PHE B 1 37  ? 165.026 173.326 187.598 1.00 45.39  ? 37  PHE B CZ  1 
ATOM   4055  N  N   . LYS B 1 38  ? 169.694 172.972 185.536 1.00 51.40  ? 38  LYS B N   1 
ATOM   4056  C  CA  . LYS B 1 38  ? 169.536 173.954 184.471 1.00 51.40  ? 38  LYS B CA  1 
ATOM   4057  C  C   . LYS B 1 38  ? 168.063 174.013 184.090 1.00 51.40  ? 38  LYS B C   1 
ATOM   4058  O  O   . LYS B 1 38  ? 167.485 173.008 183.665 1.00 51.40  ? 38  LYS B O   1 
ATOM   4059  C  CB  . LYS B 1 38  ? 170.396 173.597 183.263 1.00 51.40  ? 38  LYS B CB  1 
ATOM   4060  C  CG  . LYS B 1 38  ? 170.297 174.604 182.133 1.00 51.40  ? 38  LYS B CG  1 
ATOM   4061  C  CD  . LYS B 1 38  ? 171.189 174.230 180.966 1.00 51.40  ? 38  LYS B CD  1 
ATOM   4062  C  CE  . LYS B 1 38  ? 171.109 175.276 179.873 1.00 51.40  ? 38  LYS B CE  1 
ATOM   4063  N  NZ  . LYS B 1 38  ? 169.763 175.295 179.247 1.00 51.40  ? 38  LYS B NZ  1 
ATOM   4064  N  N   . ASP B 1 39  ? 167.459 175.189 184.240 1.00 58.09  ? 39  ASP B N   1 
ATOM   4065  C  CA  . ASP B 1 39  ? 166.046 175.390 183.926 1.00 58.09  ? 39  ASP B CA  1 
ATOM   4066  C  C   . ASP B 1 39  ? 165.954 175.841 182.475 1.00 58.09  ? 39  ASP B C   1 
ATOM   4067  O  O   . ASP B 1 39  ? 166.509 176.869 182.084 1.00 58.09  ? 39  ASP B O   1 
ATOM   4068  C  CB  . ASP B 1 39  ? 165.426 176.402 184.880 1.00 58.09  ? 39  ASP B CB  1 
ATOM   4069  C  CG  . ASP B 1 39  ? 163.919 176.455 184.776 1.00 58.09  ? 39  ASP B CG  1 
ATOM   4070  O  OD1 . ASP B 1 39  ? 163.351 175.718 183.947 1.00 58.09  ? 39  ASP B OD1 1 
ATOM   4071  O  OD2 . ASP B 1 39  ? 163.300 177.236 185.525 1.00 58.09  ? 39  ASP B OD2 1 
ATOM   4072  N  N   . ARG B 1 40  ? 165.249 175.056 181.658 1.00 68.71  ? 40  ARG B N   1 
ATOM   4073  C  CA  . ARG B 1 40  ? 165.104 175.406 180.250 1.00 68.71  ? 40  ARG B CA  1 
ATOM   4074  C  C   . ARG B 1 40  ? 163.804 176.139 179.953 1.00 68.71  ? 40  ARG B C   1 
ATOM   4075  O  O   . ARG B 1 40  ? 163.612 176.581 178.815 1.00 68.71  ? 40  ARG B O   1 
ATOM   4076  C  CB  . ARG B 1 40  ? 165.213 174.156 179.376 1.00 68.71  ? 40  ARG B CB  1 
ATOM   4077  C  CG  . ARG B 1 40  ? 164.128 173.122 179.596 1.00 68.71  ? 40  ARG B CG  1 
ATOM   4078  C  CD  . ARG B 1 40  ? 164.385 171.894 178.731 1.00 68.71  ? 40  ARG B CD  1 
ATOM   4079  N  NE  . ARG B 1 40  ? 163.358 170.871 178.899 1.00 68.71  ? 40  ARG B NE  1 
ATOM   4080  C  CZ  . ARG B 1 40  ? 163.411 169.909 179.814 1.00 68.71  ? 40  ARG B CZ  1 
ATOM   4081  N  NH1 . ARG B 1 40  ? 164.445 169.836 180.640 1.00 68.71  ? 40  ARG B NH1 1 
ATOM   4082  N  NH2 . ARG B 1 40  ? 162.433 169.017 179.900 1.00 68.71  ? 40  ARG B NH2 1 
ATOM   4083  N  N   . SER B 1 41  ? 162.914 176.281 180.934 1.00 65.89  ? 41  SER B N   1 
ATOM   4084  C  CA  . SER B 1 41  ? 161.744 177.138 180.814 1.00 65.89  ? 41  SER B CA  1 
ATOM   4085  C  C   . SER B 1 41  ? 162.005 178.539 181.352 1.00 65.89  ? 41  SER B C   1 
ATOM   4086  O  O   . SER B 1 41  ? 161.066 179.226 181.766 1.00 65.89  ? 41  SER B O   1 
ATOM   4087  C  CB  . SER B 1 41  ? 160.550 176.513 181.535 1.00 65.89  ? 41  SER B CB  1 
ATOM   4088  O  OG  . SER B 1 41  ? 159.424 177.370 181.478 1.00 65.89  ? 41  SER B OG  1 
ATOM   4089  N  N   . HIS B 1 42  ? 163.262 178.972 181.354 1.00 61.46  ? 42  HIS B N   1 
ATOM   4090  C  CA  . HIS B 1 42  ? 163.665 180.252 181.934 1.00 61.46  ? 42  HIS B CA  1 
ATOM   4091  C  C   . HIS B 1 42  ? 163.544 181.392 180.930 1.00 61.46  ? 42  HIS B C   1 
ATOM   4092  O  O   . HIS B 1 42  ? 163.016 182.460 181.235 1.00 61.46  ? 42  HIS B O   1 
ATOM   4093  C  CB  . HIS B 1 42  ? 165.087 180.144 182.466 1.00 61.46  ? 42  HIS B CB  1 
ATOM   4094  C  CG  . HIS B 1 42  ? 165.561 181.371 183.178 1.00 61.46  ? 42  HIS B CG  1 
ATOM   4095  N  ND1 . HIS B 1 42  ? 166.148 182.429 182.521 1.00 61.46  ? 42  HIS B ND1 1 
ATOM   4096  C  CD2 . HIS B 1 42  ? 165.540 181.705 184.489 1.00 61.46  ? 42  HIS B CD2 1 
ATOM   4097  C  CE1 . HIS B 1 42  ? 166.468 183.365 183.396 1.00 61.46  ? 42  HIS B CE1 1 
ATOM   4098  N  NE2 . HIS B 1 42  ? 166.109 182.950 184.598 1.00 61.46  ? 42  HIS B NE2 1 
ATOM   4099  N  N   . SER B 1 43  ? 164.047 181.167 179.716 1.00 62.94  ? 43  SER B N   1 
ATOM   4100  C  CA  . SER B 1 43  ? 164.009 182.185 178.669 1.00 62.94  ? 43  SER B CA  1 
ATOM   4101  C  C   . SER B 1 43  ? 162.619 182.705 178.352 1.00 62.94  ? 43  SER B C   1 
ATOM   4102  O  O   . SER B 1 43  ? 162.498 183.876 177.977 1.00 62.94  ? 43  SER B O   1 
ATOM   4103  C  CB  . SER B 1 43  ? 164.640 181.650 177.380 1.00 62.94  ? 43  SER B CB  1 
ATOM   4104  O  OG  . SER B 1 43  ? 166.019 181.380 177.562 1.00 62.94  ? 43  SER B OG  1 
ATOM   4105  N  N   . GLY B 1 44  ? 161.564 181.901 178.489 1.00 62.83  ? 44  GLY B N   1 
ATOM   4106  C  CA  . GLY B 1 44  ? 160.226 182.397 178.229 1.00 62.83  ? 44  GLY B CA  1 
ATOM   4107  C  C   . GLY B 1 44  ? 159.606 183.114 179.406 1.00 62.83  ? 44  GLY B C   1 
ATOM   4108  O  O   . GLY B 1 44  ? 158.735 183.970 179.221 1.00 62.83  ? 44  GLY B O   1 
ATOM   4109  N  N   . ARG B 1 45  ? 160.040 182.788 180.624 1.00 63.89  ? 45  ARG B N   1 
ATOM   4110  C  CA  . ARG B 1 45  ? 159.485 183.429 181.810 1.00 63.89  ? 45  ARG B CA  1 
ATOM   4111  C  C   . ARG B 1 45  ? 160.050 184.826 182.025 1.00 63.89  ? 45  ARG B C   1 
ATOM   4112  O  O   . ARG B 1 45  ? 159.403 185.652 182.679 1.00 63.89  ? 45  ARG B O   1 
ATOM   4113  C  CB  . ARG B 1 45  ? 159.733 182.547 183.035 1.00 63.89  ? 45  ARG B CB  1 
ATOM   4114  C  CG  . ARG B 1 45  ? 159.089 183.040 184.317 1.00 63.89  ? 45  ARG B CG  1 
ATOM   4115  C  CD  . ARG B 1 45  ? 159.214 182.004 185.422 1.00 63.89  ? 45  ARG B CD  1 
ATOM   4116  N  NE  . ARG B 1 45  ? 160.605 181.721 185.751 1.00 63.89  ? 45  ARG B NE  1 
ATOM   4117  C  CZ  . ARG B 1 45  ? 161.200 180.558 185.518 1.00 63.89  ? 45  ARG B CZ  1 
ATOM   4118  N  NH1 . ARG B 1 45  ? 160.523 179.569 184.952 1.00 63.89  ? 45  ARG B NH1 1 
ATOM   4119  N  NH2 . ARG B 1 45  ? 162.472 180.383 185.847 1.00 63.89  ? 45  ARG B NH2 1 
ATOM   4120  N  N   . VAL B 1 46  ? 161.231 185.114 181.489 1.00 63.13  ? 46  VAL B N   1 
ATOM   4121  C  CA  . VAL B 1 46  ? 161.772 186.465 181.483 1.00 63.13  ? 46  VAL B CA  1 
ATOM   4122  C  C   . VAL B 1 46  ? 161.143 187.310 180.383 1.00 63.13  ? 46  VAL B C   1 
ATOM   4123  O  O   . VAL B 1 46  ? 160.779 188.464 180.612 1.00 63.13  ? 46  VAL B O   1 
ATOM   4124  C  CB  . VAL B 1 46  ? 163.308 186.427 181.339 1.00 63.13  ? 46  VAL B CB  1 
ATOM   4125  C  CG1 . VAL B 1 46  ? 163.867 187.834 181.285 1.00 63.13  ? 46  VAL B CG1 1 
ATOM   4126  C  CG2 . VAL B 1 46  ? 163.933 185.650 182.477 1.00 63.13  ? 46  VAL B CG2 1 
ATOM   4127  N  N   . ALA B 1 47  ? 160.998 186.739 179.186 1.00 63.05  ? 47  ALA B N   1 
ATOM   4128  C  CA  . ALA B 1 47  ? 160.410 187.479 178.075 1.00 63.05  ? 47  ALA B CA  1 
ATOM   4129  C  C   . ALA B 1 47  ? 158.941 187.786 178.334 1.00 63.05  ? 47  ALA B C   1 
ATOM   4130  O  O   . ALA B 1 47  ? 158.511 188.940 178.228 1.00 63.05  ? 47  ALA B O   1 
ATOM   4131  C  CB  . ALA B 1 47  ? 160.577 186.694 176.777 1.00 63.05  ? 47  ALA B CB  1 
ATOM   4132  N  N   . GLN B 1 48  ? 158.153 186.768 178.684 1.00 64.73  ? 48  GLN B N   1 
ATOM   4133  C  CA  . GLN B 1 48  ? 156.749 187.003 179.003 1.00 64.73  ? 48  GLN B CA  1 
ATOM   4134  C  C   . GLN B 1 48  ? 156.591 187.768 180.311 1.00 64.73  ? 48  GLN B C   1 
ATOM   4135  O  O   . GLN B 1 48  ? 155.479 188.165 180.670 1.00 64.73  ? 48  GLN B O   1 
ATOM   4136  C  CB  . GLN B 1 48  ? 155.965 185.689 179.072 1.00 64.73  ? 48  GLN B CB  1 
ATOM   4137  C  CG  . GLN B 1 48  ? 155.508 185.153 177.724 1.00 64.73  ? 48  GLN B CG  1 
ATOM   4138  C  CD  . GLN B 1 48  ? 156.638 184.591 176.893 1.00 64.73  ? 48  GLN B CD  1 
ATOM   4139  O  OE1 . GLN B 1 48  ? 156.929 185.086 175.805 1.00 64.73  ? 48  GLN B OE1 1 
ATOM   4140  N  NE2 . GLN B 1 48  ? 157.272 183.539 177.394 1.00 64.73  ? 48  GLN B NE2 1 
ATOM   4141  N  N   . GLY B 1 49  ? 157.689 187.979 181.030 1.00 60.44  ? 49  GLY B N   1 
ATOM   4142  C  CA  . GLY B 1 49  ? 157.717 188.782 182.232 1.00 60.44  ? 49  GLY B CA  1 
ATOM   4143  C  C   . GLY B 1 49  ? 157.895 190.245 181.873 1.00 60.44  ? 49  GLY B C   1 
ATOM   4144  O  O   . GLY B 1 49  ? 157.288 191.137 182.492 1.00 60.44  ? 49  GLY B O   1 
ATOM   4145  N  N   . ILE B 1 50  ? 158.713 190.520 180.858 1.00 62.51  ? 50  ILE B N   1 
ATOM   4146  C  CA  . ILE B 1 50  ? 158.992 191.889 180.440 1.00 62.51  ? 50  ILE B CA  1 
ATOM   4147  C  C   . ILE B 1 50  ? 157.877 192.418 179.548 1.00 62.51  ? 50  ILE B C   1 
ATOM   4148  O  O   . ILE B 1 50  ? 157.471 193.578 179.674 1.00 62.51  ? 50  ILE B O   1 
ATOM   4149  C  CB  . ILE B 1 50  ? 160.352 191.984 179.726 1.00 62.51  ? 50  ILE B CB  1 
ATOM   4150  C  CG1 . ILE B 1 50  ? 161.485 191.656 180.695 1.00 62.51  ? 50  ILE B CG1 1 
ATOM   4151  C  CG2 . ILE B 1 50  ? 160.552 193.365 179.131 1.00 62.51  ? 50  ILE B CG2 1 
ATOM   4152  C  CD1 . ILE B 1 50  ? 162.815 191.497 180.019 1.00 62.51  ? 50  ILE B CD1 1 
ATOM   4153  N  N   . MET B 1 51  ? 157.370 191.585 178.636 1.00 64.46  ? 51  MET B N   1 
ATOM   4154  C  CA  . MET B 1 51  ? 156.329 192.069 177.736 1.00 64.46  ? 51  MET B CA  1 
ATOM   4155  C  C   . MET B 1 51  ? 154.983 192.211 178.430 1.00 64.46  ? 51  MET B C   1 
ATOM   4156  O  O   . MET B 1 51  ? 154.051 192.759 177.834 1.00 64.46  ? 51  MET B O   1 
ATOM   4157  C  CB  . MET B 1 51  ? 156.183 191.149 176.525 1.00 64.46  ? 51  MET B CB  1 
ATOM   4158  C  CG  . MET B 1 51  ? 155.639 189.774 176.842 1.00 64.46  ? 51  MET B CG  1 
ATOM   4159  S  SD  . MET B 1 51  ? 155.518 188.742 175.370 1.00 64.46  ? 51  MET B SD  1 
ATOM   4160  C  CE  . MET B 1 51  ? 157.245 188.390 175.059 1.00 64.46  ? 51  MET B CE  1 
ATOM   4161  N  N   . LYS B 1 52  ? 154.860 191.733 179.664 1.00 67.88  ? 52  LYS B N   1 
ATOM   4162  C  CA  . LYS B 1 52  ? 153.626 191.829 180.434 1.00 67.88  ? 52  LYS B CA  1 
ATOM   4163  C  C   . LYS B 1 52  ? 153.739 192.758 181.630 1.00 67.88  ? 52  LYS B C   1 
ATOM   4164  O  O   . LYS B 1 52  ? 152.774 193.446 181.964 1.00 67.88  ? 52  LYS B O   1 
ATOM   4165  C  CB  . LYS B 1 52  ? 153.191 190.434 180.904 1.00 67.88  ? 52  LYS B CB  1 
ATOM   4166  C  CG  . LYS B 1 52  ? 151.890 190.390 181.693 1.00 67.88  ? 52  LYS B CG  1 
ATOM   4167  C  CD  . LYS B 1 52  ? 152.141 190.331 183.194 1.00 67.88  ? 52  LYS B CD  1 
ATOM   4168  C  CE  . LYS B 1 52  ? 152.703 188.978 183.597 1.00 67.88  ? 52  LYS B CE  1 
ATOM   4169  N  NZ  . LYS B 1 52  ? 152.946 188.885 185.061 1.00 67.88  ? 52  LYS B NZ  1 
ATOM   4170  N  N   . LEU B 1 53  ? 154.894 192.796 182.288 1.00 67.85  ? 53  LEU B N   1 
ATOM   4171  C  CA  . LEU B 1 53  ? 155.100 193.706 183.407 1.00 67.85  ? 53  LEU B CA  1 
ATOM   4172  C  C   . LEU B 1 53  ? 155.624 195.060 182.946 1.00 67.85  ? 53  LEU B C   1 
ATOM   4173  O  O   . LEU B 1 53  ? 155.498 196.054 183.667 1.00 67.85  ? 53  LEU B O   1 
ATOM   4174  C  CB  . LEU B 1 53  ? 156.060 193.070 184.419 1.00 67.85  ? 53  LEU B CB  1 
ATOM   4175  C  CG  . LEU B 1 53  ? 156.319 193.736 185.772 1.00 67.85  ? 53  LEU B CG  1 
ATOM   4176  C  CD1 . LEU B 1 53  ? 156.566 192.673 186.821 1.00 67.85  ? 53  LEU B CD1 1 
ATOM   4177  C  CD2 . LEU B 1 53  ? 157.516 194.668 185.698 1.00 67.85  ? 53  LEU B CD2 1 
ATOM   4178  N  N   . CYS B 1 54  ? 156.188 195.115 181.744 1.00 70.69  ? 54  CYS B N   1 
ATOM   4179  C  CA  . CYS B 1 54  ? 156.829 196.308 181.209 1.00 70.69  ? 54  CYS B CA  1 
ATOM   4180  C  C   . CYS B 1 54  ? 155.889 197.192 180.402 1.00 70.69  ? 54  CYS B C   1 
ATOM   4181  O  O   . CYS B 1 54  ? 155.578 198.303 180.840 1.00 70.69  ? 54  CYS B O   1 
ATOM   4182  C  CB  . CYS B 1 54  ? 158.022 195.908 180.336 1.00 70.69  ? 54  CYS B CB  1 
ATOM   4183  S  SG  . CYS B 1 54  ? 158.890 197.283 179.562 1.00 70.69  ? 54  CYS B SG  1 
ATOM   4184  N  N   . LEU B 1 55  ? 155.428 196.730 179.240 1.00 68.10  ? 55  LEU B N   1 
ATOM   4185  C  CA  . LEU B 1 55  ? 154.662 197.581 178.338 1.00 68.10  ? 55  LEU B CA  1 
ATOM   4186  C  C   . LEU B 1 55  ? 153.184 197.543 178.714 1.00 68.10  ? 55  LEU B C   1 
ATOM   4187  O  O   . LEU B 1 55  ? 152.306 197.703 177.860 1.00 68.10  ? 55  LEU B O   1 
ATOM   4188  C  CB  . LEU B 1 55  ? 154.895 197.144 176.886 1.00 68.10  ? 55  LEU B CB  1 
ATOM   4189  C  CG  . LEU B 1 55  ? 154.442 198.042 175.729 1.00 68.10  ? 55  LEU B CG  1 
ATOM   4190  C  CD1 . LEU B 1 55  ? 155.159 199.381 175.775 1.00 68.10  ? 55  LEU B CD1 1 
ATOM   4191  C  CD2 . LEU B 1 55  ? 154.687 197.359 174.398 1.00 68.10  ? 55  LEU B CD2 1 
ATOM   4192  N  N   . GLU B 1 56  ? 152.899 197.333 180.000 1.00 76.51  ? 56  GLU B N   1 
ATOM   4193  C  CA  . GLU B 1 56  ? 151.516 197.355 180.465 1.00 76.51  ? 56  GLU B CA  1 
ATOM   4194  C  C   . GLU B 1 56  ? 151.350 198.304 181.644 1.00 76.51  ? 56  GLU B C   1 
ATOM   4195  O  O   . GLU B 1 56  ? 150.580 199.268 181.570 1.00 76.51  ? 56  GLU B O   1 
ATOM   4196  C  CB  . GLU B 1 56  ? 151.065 195.947 180.849 1.00 76.51  ? 56  GLU B CB  1 
ATOM   4197  C  CG  . GLU B 1 56  ? 151.009 194.972 179.689 1.00 76.51  ? 56  GLU B CG  1 
ATOM   4198  C  CD  . GLU B 1 56  ? 149.936 195.326 178.685 1.00 76.51  ? 56  GLU B CD  1 
ATOM   4199  O  OE1 . GLU B 1 56  ? 148.896 195.881 179.095 1.00 76.51  ? 56  GLU B OE1 1 
ATOM   4200  O  OE2 . GLU B 1 56  ? 150.134 195.046 177.484 1.00 76.51  ? 56  GLU B OE2 1 
ATOM   4201  N  N   . GLU B 1 57  ? 152.064 198.048 182.738 1.00 79.51  ? 57  GLU B N   1 
ATOM   4202  C  CA  . GLU B 1 57  ? 152.026 198.909 183.908 1.00 79.51  ? 57  GLU B CA  1 
ATOM   4203  C  C   . GLU B 1 57  ? 153.109 199.978 183.904 1.00 79.51  ? 57  GLU B C   1 
ATOM   4204  O  O   . GLU B 1 57  ? 153.302 200.636 184.932 1.00 79.51  ? 57  GLU B O   1 
ATOM   4205  C  CB  . GLU B 1 57  ? 152.149 198.070 185.189 1.00 79.51  ? 57  GLU B CB  1 
ATOM   4206  C  CG  . GLU B 1 57  ? 150.975 197.142 185.455 1.00 79.51  ? 57  GLU B CG  1 
ATOM   4207  C  CD  . GLU B 1 57  ? 151.093 195.824 184.718 1.00 79.51  ? 57  GLU B CD  1 
ATOM   4208  O  OE1 . GLU B 1 57  ? 152.117 195.614 184.036 1.00 79.51  ? 57  GLU B OE1 1 
ATOM   4209  O  OE2 . GLU B 1 57  ? 150.166 194.995 184.826 1.00 79.51  ? 57  GLU B OE2 1 
ATOM   4210  N  N   . GLU B 1 58  ? 153.816 200.160 182.781 1.00 78.20  ? 58  GLU B N   1 
ATOM   4211  C  CA  . GLU B 1 58  ? 154.894 201.133 182.594 1.00 78.20  ? 58  GLU B CA  1 
ATOM   4212  C  C   . GLU B 1 58  ? 155.809 201.256 183.809 1.00 78.20  ? 58  GLU B C   1 
ATOM   4213  O  O   . GLU B 1 58  ? 156.361 202.326 184.076 1.00 78.20  ? 58  GLU B O   1 
ATOM   4214  C  CB  . GLU B 1 58  ? 154.314 202.504 182.197 1.00 78.20  ? 58  GLU B CB  1 
ATOM   4215  C  CG  . GLU B 1 58  ? 153.376 203.180 183.202 1.00 78.20  ? 58  GLU B CG  1 
ATOM   4216  C  CD  . GLU B 1 58  ? 154.076 204.172 184.115 1.00 78.20  ? 58  GLU B CD  1 
ATOM   4217  O  OE1 . GLU B 1 58  ? 155.147 204.690 183.734 1.00 78.20  ? 58  GLU B OE1 1 
ATOM   4218  O  OE2 . GLU B 1 58  ? 153.552 204.436 185.218 1.00 78.20  ? 58  GLU B OE2 1 
ATOM   4219  N  N   . LEU B 1 59  ? 156.011 200.155 184.525 1.00 70.33  ? 59  LEU B N   1 
ATOM   4220  C  CA  . LEU B 1 59  ? 156.765 200.156 185.767 1.00 70.33  ? 59  LEU B CA  1 
ATOM   4221  C  C   . LEU B 1 59  ? 158.264 200.173 185.490 1.00 70.33  ? 59  LEU B C   1 
ATOM   4222  O  O   . LEU B 1 59  ? 158.745 199.605 184.507 1.00 70.33  ? 59  LEU B O   1 
ATOM   4223  C  CB  . LEU B 1 59  ? 156.410 198.937 186.628 1.00 70.33  ? 59  LEU B CB  1 
ATOM   4224  C  CG  . LEU B 1 59  ? 154.996 198.875 187.203 1.00 70.33  ? 59  LEU B CG  1 
ATOM   4225  C  CD1 . LEU B 1 59  ? 154.755 197.537 187.877 1.00 70.33  ? 59  LEU B CD1 1 
ATOM   4226  C  CD2 . LEU B 1 59  ? 154.765 200.017 188.179 1.00 70.33  ? 59  LEU B CD2 1 
ATOM   4227  N  N   . PHE B 1 60  ? 158.989 200.859 186.372 1.00 61.64  ? 60  PHE B N   1 
ATOM   4228  C  CA  . PHE B 1 60  ? 160.448 200.811 186.464 1.00 61.64  ? 60  PHE B CA  1 
ATOM   4229  C  C   . PHE B 1 60  ? 161.142 201.471 185.276 1.00 61.64  ? 60  PHE B C   1 
ATOM   4230  O  O   . PHE B 1 60  ? 162.306 201.168 184.997 1.00 61.64  ? 60  PHE B O   1 
ATOM   4231  C  CB  . PHE B 1 60  ? 160.948 199.370 186.621 1.00 61.64  ? 60  PHE B CB  1 
ATOM   4232  C  CG  . PHE B 1 60  ? 160.370 198.657 187.809 1.00 61.64  ? 60  PHE B CG  1 
ATOM   4233  C  CD1 . PHE B 1 60  ? 160.785 198.964 189.089 1.00 61.64  ? 60  PHE B CD1 1 
ATOM   4234  C  CD2 . PHE B 1 60  ? 159.428 197.660 187.639 1.00 61.64  ? 60  PHE B CD2 1 
ATOM   4235  C  CE1 . PHE B 1 60  ? 160.252 198.307 190.175 1.00 61.64  ? 60  PHE B CE1 1 
ATOM   4236  C  CE2 . PHE B 1 60  ? 158.894 197.000 188.724 1.00 61.64  ? 60  PHE B CE2 1 
ATOM   4237  C  CZ  . PHE B 1 60  ? 159.308 197.322 189.992 1.00 61.64  ? 60  PHE B CZ  1 
ATOM   4238  N  N   . ALA B 1 61  ? 160.462 202.377 184.577 1.00 60.23  ? 61  ALA B N   1 
ATOM   4239  C  CA  . ALA B 1 61  ? 161.069 203.061 183.441 1.00 60.23  ? 61  ALA B CA  1 
ATOM   4240  C  C   . ALA B 1 61  ? 162.240 203.923 183.893 1.00 60.23  ? 61  ALA B C   1 
ATOM   4241  O  O   . ALA B 1 61  ? 162.269 204.415 185.024 1.00 60.23  ? 61  ALA B O   1 
ATOM   4242  C  CB  . ALA B 1 61  ? 160.031 203.923 182.726 1.00 60.23  ? 61  ALA B CB  1 
ATOM   4243  N  N   . ASP B 1 62  ? 163.216 204.109 183.000 1.00 56.43  ? 62  ASP B N   1 
ATOM   4244  C  CA  . ASP B 1 62  ? 164.398 204.890 183.332 1.00 56.43  ? 62  ASP B CA  1 
ATOM   4245  C  C   . ASP B 1 62  ? 165.036 205.619 182.156 1.00 56.43  ? 62  ASP B C   1 
ATOM   4246  O  O   . ASP B 1 62  ? 166.169 206.092 182.292 1.00 56.43  ? 62  ASP B O   1 
ATOM   4247  C  CB  . ASP B 1 62  ? 165.455 204.000 184.005 1.00 56.43  ? 62  ASP B CB  1 
ATOM   4248  C  CG  . ASP B 1 62  ? 165.910 202.858 183.123 1.00 56.43  ? 62  ASP B CG  1 
ATOM   4249  O  OD1 . ASP B 1 62  ? 165.374 202.711 182.006 1.00 56.43  ? 62  ASP B OD1 1 
ATOM   4250  O  OD2 . ASP B 1 62  ? 166.807 202.101 183.548 1.00 56.43  ? 62  ASP B OD2 1 
ATOM   4251  N  N   . VAL B 1 63  ? 164.361 205.723 181.013 1.00 59.18  ? 63  VAL B N   1 
ATOM   4252  C  CA  . VAL B 1 63  ? 164.816 206.583 179.925 1.00 59.18  ? 63  VAL B CA  1 
ATOM   4253  C  C   . VAL B 1 63  ? 163.590 207.086 179.179 1.00 59.18  ? 63  VAL B C   1 
ATOM   4254  O  O   . VAL B 1 63  ? 162.582 206.381 179.077 1.00 59.18  ? 63  VAL B O   1 
ATOM   4255  C  CB  . VAL B 1 63  ? 165.796 205.855 178.979 1.00 59.18  ? 63  VAL B CB  1 
ATOM   4256  C  CG1 . VAL B 1 63  ? 165.093 204.774 178.184 1.00 59.18  ? 63  VAL B CG1 1 
ATOM   4257  C  CG2 . VAL B 1 63  ? 166.486 206.842 178.056 1.00 59.18  ? 63  VAL B CG2 1 
ATOM   4258  N  N   . THR B 1 64  ? 163.659 208.319 178.684 1.00 69.01  ? 64  THR B N   1 
ATOM   4259  C  CA  . THR B 1 64  ? 162.554 208.929 177.954 1.00 69.01  ? 64  THR B CA  1 
ATOM   4260  C  C   . THR B 1 64  ? 163.008 209.231 176.535 1.00 69.01  ? 64  THR B C   1 
ATOM   4261  O  O   . THR B 1 64  ? 163.817 210.140 176.315 1.00 69.01  ? 64  THR B O   1 
ATOM   4262  C  CB  . THR B 1 64  ? 162.060 210.198 178.648 1.00 69.01  ? 64  THR B CB  1 
ATOM   4263  O  OG1 . THR B 1 64  ? 163.129 211.145 178.733 1.00 69.01  ? 64  THR B OG1 1 
ATOM   4264  C  CG2 . THR B 1 64  ? 161.559 209.878 180.046 1.00 69.01  ? 64  THR B CG2 1 
ATOM   4265  N  N   . ILE B 1 65  ? 162.491 208.462 175.580 1.00 65.16  ? 65  ILE B N   1 
ATOM   4266  C  CA  . ILE B 1 65  ? 162.802 208.630 174.167 1.00 65.16  ? 65  ILE B CA  1 
ATOM   4267  C  C   . ILE B 1 65  ? 161.687 209.446 173.533 1.00 65.16  ? 65  ILE B C   1 
ATOM   4268  O  O   . ILE B 1 65  ? 160.571 208.948 173.345 1.00 65.16  ? 65  ILE B O   1 
ATOM   4269  C  CB  . ILE B 1 65  ? 162.959 207.275 173.461 1.00 65.16  ? 65  ILE B CB  1 
ATOM   4270  C  CG1 . ILE B 1 65  ? 164.095 206.470 174.091 1.00 65.16  ? 65  ILE B CG1 1 
ATOM   4271  C  CG2 . ILE B 1 65  ? 163.218 207.475 171.986 1.00 65.16  ? 65  ILE B CG2 1 
ATOM   4272  C  CD1 . ILE B 1 65  ? 165.442 207.130 173.974 1.00 65.16  ? 65  ILE B CD1 1 
ATOM   4273  N  N   . SER B 1 66  ? 161.984 210.700 173.212 1.00 68.01  ? 66  SER B N   1 
ATOM   4274  C  CA  . SER B 1 66  ? 161.036 211.603 172.573 1.00 68.01  ? 66  SER B CA  1 
ATOM   4275  C  C   . SER B 1 66  ? 161.360 211.673 171.090 1.00 68.01  ? 66  SER B C   1 
ATOM   4276  O  O   . SER B 1 66  ? 162.511 211.922 170.715 1.00 68.01  ? 66  SER B O   1 
ATOM   4277  C  CB  . SER B 1 66  ? 161.090 212.994 173.202 1.00 68.01  ? 66  SER B CB  1 
ATOM   4278  O  OG  . SER B 1 66  ? 160.188 213.874 172.555 1.00 68.01  ? 66  SER B OG  1 
ATOM   4279  N  N   . VAL B 1 67  ? 160.350 211.453 170.252 1.00 68.29  ? 67  VAL B N   1 
ATOM   4280  C  CA  . VAL B 1 67  ? 160.509 211.461 168.803 1.00 68.29  ? 67  VAL B CA  1 
ATOM   4281  C  C   . VAL B 1 67  ? 159.376 212.276 168.192 1.00 68.29  ? 67  VAL B C   1 
ATOM   4282  O  O   . VAL B 1 67  ? 158.200 212.035 168.495 1.00 68.29  ? 67  VAL B O   1 
ATOM   4283  C  CB  . VAL B 1 67  ? 160.552 210.037 168.219 1.00 68.29  ? 67  VAL B CB  1 
ATOM   4284  C  CG1 . VAL B 1 67  ? 159.305 209.249 168.587 1.00 68.29  ? 67  VAL B CG1 1 
ATOM   4285  C  CG2 . VAL B 1 67  ? 160.713 210.095 166.716 1.00 68.29  ? 67  VAL B CG2 1 
ATOM   4286  N  N   . GLU B 1 68  ? 159.739 213.257 167.359 1.00 70.32  ? 68  GLU B N   1 
ATOM   4287  C  CA  . GLU B 1 68  ? 158.802 214.137 166.647 1.00 70.32  ? 68  GLU B CA  1 
ATOM   4288  C  C   . GLU B 1 68  ? 157.562 214.472 167.475 1.00 70.32  ? 68  GLU B C   1 
ATOM   4289  O  O   . GLU B 1 68  ? 156.433 214.445 166.982 1.00 70.32  ? 68  GLU B O   1 
ATOM   4290  C  CB  . GLU B 1 68  ? 158.407 213.540 165.296 1.00 70.32  ? 68  GLU B CB  1 
ATOM   4291  C  CG  . GLU B 1 68  ? 159.537 213.529 164.277 1.00 70.32  ? 68  GLU B CG  1 
ATOM   4292  C  CD  . GLU B 1 68  ? 159.106 212.986 162.929 1.00 70.32  ? 68  GLU B CD  1 
ATOM   4293  O  OE1 . GLU B 1 68  ? 157.958 212.507 162.816 1.00 70.32  ? 68  GLU B OE1 1 
ATOM   4294  O  OE2 . GLU B 1 68  ? 159.914 213.042 161.980 1.00 70.32  ? 68  GLU B OE2 1 
ATOM   4295  N  N   . GLY B 1 69  ? 157.775 214.786 168.749 1.00 70.87  ? 69  GLY B N   1 
ATOM   4296  C  CA  . GLY B 1 69  ? 156.695 215.262 169.590 1.00 70.87  ? 69  GLY B CA  1 
ATOM   4297  C  C   . GLY B 1 69  ? 156.023 214.220 170.462 1.00 70.87  ? 69  GLY B C   1 
ATOM   4298  O  O   . GLY B 1 69  ? 154.872 214.407 170.867 1.00 70.87  ? 69  GLY B O   1 
ATOM   4299  N  N   . ARG B 1 70  ? 156.710 213.122 170.760 1.00 71.36  ? 70  ARG B N   1 
ATOM   4300  C  CA  . ARG B 1 70  ? 156.163 212.174 171.720 1.00 71.36  ? 70  ARG B CA  1 
ATOM   4301  C  C   . ARG B 1 70  ? 157.222 211.742 172.731 1.00 71.36  ? 70  ARG B C   1 
ATOM   4302  O  O   . ARG B 1 70  ? 158.385 211.503 172.397 1.00 71.36  ? 70  ARG B O   1 
ATOM   4303  C  CB  . ARG B 1 70  ? 155.589 210.946 171.016 1.00 71.36  ? 70  ARG B CB  1 
ATOM   4304  C  CG  . ARG B 1 70  ? 154.338 211.223 170.205 1.00 71.36  ? 70  ARG B CG  1 
ATOM   4305  C  CD  . ARG B 1 70  ? 153.750 209.937 169.656 1.00 71.36  ? 70  ARG B CD  1 
ATOM   4306  N  NE  . ARG B 1 70  ? 153.234 209.092 170.729 1.00 71.36  ? 70  ARG B NE  1 
ATOM   4307  C  CZ  . ARG B 1 70  ? 152.819 207.842 170.564 1.00 71.36  ? 70  ARG B CZ  1 
ATOM   4308  N  NH1 . ARG B 1 70  ? 152.859 207.281 169.364 1.00 71.36  ? 70  ARG B NH1 1 
ATOM   4309  N  NH2 . ARG B 1 70  ? 152.366 207.151 171.601 1.00 71.36  ? 70  ARG B NH2 1 
ATOM   4310  N  N   . GLU B 1 71  ? 156.793 211.643 173.988 1.00 71.84  ? 71  GLU B N   1 
ATOM   4311  C  CA  . GLU B 1 71  ? 157.619 211.150 175.085 1.00 71.84  ? 71  GLU B CA  1 
ATOM   4312  C  C   . GLU B 1 71  ? 157.322 209.669 175.270 1.00 71.84  ? 71  GLU B C   1 
ATOM   4313  O  O   . GLU B 1 71  ? 156.161 209.281 175.435 1.00 71.84  ? 71  GLU B O   1 
ATOM   4314  C  CB  . GLU B 1 71  ? 157.341 211.925 176.374 1.00 71.84  ? 71  GLU B CB  1 
ATOM   4315  C  CG  . GLU B 1 71  ? 157.762 213.386 176.350 1.00 71.84  ? 71  GLU B CG  1 
ATOM   4316  C  CD  . GLU B 1 71  ? 159.266 213.560 176.350 1.00 71.84  ? 71  GLU B CD  1 
ATOM   4317  O  OE1 . GLU B 1 71  ? 159.966 212.705 176.931 1.00 71.84  ? 71  GLU B OE1 1 
ATOM   4318  O  OE2 . GLU B 1 71  ? 159.750 214.556 175.777 1.00 71.84  ? 71  GLU B OE2 1 
ATOM   4319  N  N   . PHE B 1 72  ? 158.363 208.845 175.240 1.00 64.95  ? 72  PHE B N   1 
ATOM   4320  C  CA  . PHE B 1 72  ? 158.235 207.410 175.446 1.00 64.95  ? 72  PHE B CA  1 
ATOM   4321  C  C   . PHE B 1 72  ? 158.962 207.007 176.720 1.00 64.95  ? 72  PHE B C   1 
ATOM   4322  O  O   . PHE B 1 72  ? 160.174 207.210 176.841 1.00 64.95  ? 72  PHE B O   1 
ATOM   4323  C  CB  . PHE B 1 72  ? 158.787 206.640 174.247 1.00 64.95  ? 72  PHE B CB  1 
ATOM   4324  C  CG  . PHE B 1 72  ? 157.906 206.704 173.034 1.00 64.95  ? 72  PHE B CG  1 
ATOM   4325  C  CD1 . PHE B 1 72  ? 156.577 207.052 173.149 1.00 64.95  ? 72  PHE B CD1 1 
ATOM   4326  C  CD2 . PHE B 1 72  ? 158.408 206.434 171.778 1.00 64.95  ? 72  PHE B CD2 1 
ATOM   4327  C  CE1 . PHE B 1 72  ? 155.763 207.109 172.031 1.00 64.95  ? 72  PHE B CE1 1 
ATOM   4328  C  CE2 . PHE B 1 72  ? 157.597 206.498 170.667 1.00 64.95  ? 72  PHE B CE2 1 
ATOM   4329  C  CZ  . PHE B 1 72  ? 156.275 206.834 170.796 1.00 64.95  ? 72  PHE B CZ  1 
ATOM   4330  N  N   . GLN B 1 73  ? 158.214 206.449 177.671 1.00 63.43  ? 73  GLN B N   1 
ATOM   4331  C  CA  . GLN B 1 73  ? 158.763 206.023 178.956 1.00 63.43  ? 73  GLN B CA  1 
ATOM   4332  C  C   . GLN B 1 73  ? 159.305 204.610 178.778 1.00 63.43  ? 73  GLN B C   1 
ATOM   4333  O  O   . GLN B 1 73  ? 158.628 203.621 179.061 1.00 63.43  ? 73  GLN B O   1 
ATOM   4334  C  CB  . GLN B 1 73  ? 157.698 206.085 180.042 1.00 63.43  ? 73  GLN B CB  1 
ATOM   4335  C  CG  . GLN B 1 73  ? 157.073 207.462 180.233 1.00 63.43  ? 73  GLN B CG  1 
ATOM   4336  C  CD  . GLN B 1 73  ? 158.059 208.498 180.733 1.00 63.43  ? 73  GLN B CD  1 
ATOM   4337  O  OE1 . GLN B 1 73  ? 158.921 208.205 181.559 1.00 63.43  ? 73  GLN B OE1 1 
ATOM   4338  N  NE2 . GLN B 1 73  ? 157.930 209.723 180.237 1.00 63.43  ? 73  GLN B NE2 1 
ATOM   4339  N  N   . LEU B 1 74  ? 160.541 204.515 178.305 1.00 56.03  ? 74  LEU B N   1 
ATOM   4340  C  CA  . LEU B 1 74  ? 161.160 203.249 177.948 1.00 56.03  ? 74  LEU B CA  1 
ATOM   4341  C  C   . LEU B 1 74  ? 162.225 202.864 178.972 1.00 56.03  ? 74  LEU B C   1 
ATOM   4342  O  O   . LEU B 1 74  ? 162.624 203.656 179.834 1.00 56.03  ? 74  LEU B O   1 
ATOM   4343  C  CB  . LEU B 1 74  ? 161.758 203.329 176.543 1.00 56.03  ? 74  LEU B CB  1 
ATOM   4344  C  CG  . LEU B 1 74  ? 160.777 203.581 175.396 1.00 56.03  ? 74  LEU B CG  1 
ATOM   4345  C  CD1 . LEU B 1 74  ? 161.528 203.722 174.084 1.00 56.03  ? 74  LEU B CD1 1 
ATOM   4346  C  CD2 . LEU B 1 74  ? 159.728 202.488 175.307 1.00 56.03  ? 74  LEU B CD2 1 
ATOM   4347  N  N   . HIS B 1 75  ? 162.692 201.622 178.853 1.00 54.30  ? 75  HIS B N   1 
ATOM   4348  C  CA  . HIS B 1 75  ? 163.673 201.033 179.752 1.00 54.30  ? 75  HIS B CA  1 
ATOM   4349  C  C   . HIS B 1 75  ? 165.006 200.894 179.033 1.00 54.30  ? 75  HIS B C   1 
ATOM   4350  O  O   . HIS B 1 75  ? 165.044 200.654 177.824 1.00 54.30  ? 75  HIS B O   1 
ATOM   4351  C  CB  . HIS B 1 75  ? 163.206 199.665 180.244 1.00 54.30  ? 75  HIS B CB  1 
ATOM   4352  C  CG  . HIS B 1 75  ? 161.970 199.718 181.084 1.00 54.30  ? 75  HIS B CG  1 
ATOM   4353  N  ND1 . HIS B 1 75  ? 160.703 199.707 180.543 1.00 54.30  ? 75  HIS B ND1 1 
ATOM   4354  C  CD2 . HIS B 1 75  ? 161.806 199.773 182.425 1.00 54.30  ? 75  HIS B CD2 1 
ATOM   4355  C  CE1 . HIS B 1 75  ? 159.812 199.764 181.515 1.00 54.30  ? 75  HIS B CE1 1 
ATOM   4356  N  NE2 . HIS B 1 75  ? 160.455 199.802 182.668 1.00 54.30  ? 75  HIS B NE2 1 
ATOM   4357  N  N   . ARG B 1 76  ? 166.100 201.036 179.781 1.00 51.69  ? 76  ARG B N   1 
ATOM   4358  C  CA  . ARG B 1 76  ? 167.418 200.946 179.162 1.00 51.69  ? 76  ARG B CA  1 
ATOM   4359  C  C   . ARG B 1 76  ? 167.885 199.501 179.054 1.00 51.69  ? 76  ARG B C   1 
ATOM   4360  O  O   . ARG B 1 76  ? 168.728 199.177 178.211 1.00 51.69  ? 76  ARG B O   1 
ATOM   4361  C  CB  . ARG B 1 76  ? 168.433 201.768 179.952 1.00 51.69  ? 76  ARG B CB  1 
ATOM   4362  C  CG  . ARG B 1 76  ? 168.208 203.263 179.903 1.00 51.69  ? 76  ARG B CG  1 
ATOM   4363  C  CD  . ARG B 1 76  ? 169.286 204.004 180.678 1.00 51.69  ? 76  ARG B CD  1 
ATOM   4364  N  NE  . ARG B 1 76  ? 169.201 203.759 182.114 1.00 51.69  ? 76  ARG B NE  1 
ATOM   4365  C  CZ  . ARG B 1 76  ? 170.109 204.165 182.994 1.00 51.69  ? 76  ARG B CZ  1 
ATOM   4366  N  NH1 . ARG B 1 76  ? 171.177 204.835 182.585 1.00 51.69  ? 76  ARG B NH1 1 
ATOM   4367  N  NH2 . ARG B 1 76  ? 169.949 203.900 184.283 1.00 51.69  ? 76  ARG B NH2 1 
ATOM   4368  N  N   . LEU B 1 77  ? 167.353 198.620 179.902 1.00 49.12  ? 77  LEU B N   1 
ATOM   4369  C  CA  . LEU B 1 77  ? 167.827 197.244 179.942 1.00 49.12  ? 77  LEU B CA  1 
ATOM   4370  C  C   . LEU B 1 77  ? 167.282 196.410 178.791 1.00 49.12  ? 77  LEU B C   1 
ATOM   4371  O  O   . LEU B 1 77  ? 167.946 195.462 178.362 1.00 49.12  ? 77  LEU B O   1 
ATOM   4372  C  CB  . LEU B 1 77  ? 167.453 196.606 181.280 1.00 49.12  ? 77  LEU B CB  1 
ATOM   4373  C  CG  . LEU B 1 77  ? 167.981 195.200 181.560 1.00 49.12  ? 77  LEU B CG  1 
ATOM   4374  C  CD1 . LEU B 1 77  ? 169.497 195.210 181.600 1.00 49.12  ? 77  LEU B CD1 1 
ATOM   4375  C  CD2 . LEU B 1 77  ? 167.411 194.666 182.864 1.00 49.12  ? 77  LEU B CD2 1 
ATOM   4376  N  N   . VAL B 1 78  ? 166.101 196.741 178.279 1.00 45.95  ? 78  VAL B N   1 
ATOM   4377  C  CA  . VAL B 1 78  ? 165.518 195.984 177.177 1.00 45.95  ? 78  VAL B CA  1 
ATOM   4378  C  C   . VAL B 1 78  ? 165.934 196.562 175.830 1.00 45.95  ? 78  VAL B C   1 
ATOM   4379  O  O   . VAL B 1 78  ? 166.061 195.829 174.847 1.00 45.95  ? 78  VAL B O   1 
ATOM   4380  C  CB  . VAL B 1 78  ? 163.986 195.944 177.323 1.00 45.95  ? 78  VAL B CB  1 
ATOM   4381  C  CG1 . VAL B 1 78  ? 163.373 195.093 176.227 1.00 45.95  ? 78  VAL B CG1 1 
ATOM   4382  C  CG2 . VAL B 1 78  ? 163.597 195.433 178.697 1.00 45.95  ? 78  VAL B CG2 1 
ATOM   4383  N  N   . LEU B 1 79  ? 166.150 197.877 175.761 1.00 44.88  ? 79  LEU B N   1 
ATOM   4384  C  CA  . LEU B 1 79  ? 166.610 198.483 174.517 1.00 44.88  ? 79  LEU B CA  1 
ATOM   4385  C  C   . LEU B 1 79  ? 168.058 198.116 174.232 1.00 44.88  ? 79  LEU B C   1 
ATOM   4386  O  O   . LEU B 1 79  ? 168.447 197.941 173.072 1.00 44.88  ? 79  LEU B O   1 
ATOM   4387  C  CB  . LEU B 1 79  ? 166.450 200.001 174.577 1.00 44.88  ? 79  LEU B CB  1 
ATOM   4388  C  CG  . LEU B 1 79  ? 165.029 200.553 174.628 1.00 44.88  ? 79  LEU B CG  1 
ATOM   4389  C  CD1 . LEU B 1 79  ? 165.050 202.058 174.802 1.00 44.88  ? 79  LEU B CD1 1 
ATOM   4390  C  CD2 . LEU B 1 79  ? 164.267 200.167 173.380 1.00 44.88  ? 79  LEU B CD2 1 
ATOM   4391  N  N   . SER B 1 80  ? 168.874 197.995 175.281 1.00 50.10  ? 80  SER B N   1 
ATOM   4392  C  CA  . SER B 1 80  ? 170.281 197.659 175.101 1.00 50.10  ? 80  SER B CA  1 
ATOM   4393  C  C   . SER B 1 80  ? 170.497 196.169 174.879 1.00 50.10  ? 80  SER B C   1 
ATOM   4394  O  O   . SER B 1 80  ? 171.411 195.794 174.138 1.00 50.10  ? 80  SER B O   1 
ATOM   4395  C  CB  . SER B 1 80  ? 171.090 198.128 176.308 1.00 50.10  ? 80  SER B CB  1 
ATOM   4396  O  OG  . SER B 1 80  ? 172.451 197.770 176.170 1.00 50.10  ? 80  SER B OG  1 
ATOM   4397  N  N   . ALA B 1 81  ? 169.687 195.317 175.502 1.00 48.09  ? 81  ALA B N   1 
ATOM   4398  C  CA  . ALA B 1 81  ? 169.741 193.879 175.286 1.00 48.09  ? 81  ALA B CA  1 
ATOM   4399  C  C   . ALA B 1 81  ? 168.989 193.447 174.039 1.00 48.09  ? 81  ALA B C   1 
ATOM   4400  O  O   . ALA B 1 81  ? 168.351 192.391 174.052 1.00 48.09  ? 81  ALA B O   1 
ATOM   4401  C  CB  . ALA B 1 81  ? 169.178 193.140 176.501 1.00 48.09  ? 81  ALA B CB  1 
ATOM   4402  N  N   . GLN B 1 82  ? 169.047 194.237 172.970 1.00 49.78  ? 82  GLN B N   1 
ATOM   4403  C  CA  . GLN B 1 82  ? 168.275 193.989 171.766 1.00 49.78  ? 82  GLN B CA  1 
ATOM   4404  C  C   . GLN B 1 82  ? 168.842 194.688 170.542 1.00 49.78  ? 82  GLN B C   1 
ATOM   4405  O  O   . GLN B 1 82  ? 168.623 194.210 169.424 1.00 49.78  ? 82  GLN B O   1 
ATOM   4406  C  CB  . GLN B 1 82  ? 166.818 194.437 171.975 1.00 49.78  ? 82  GLN B CB  1 
ATOM   4407  C  CG  . GLN B 1 82  ? 165.865 194.090 170.851 1.00 49.78  ? 82  GLN B CG  1 
ATOM   4408  C  CD  . GLN B 1 82  ? 165.711 192.601 170.666 1.00 49.78  ? 82  GLN B CD  1 
ATOM   4409  O  OE1 . GLN B 1 82  ? 166.248 192.024 169.723 1.00 49.78  ? 82  GLN B OE1 1 
ATOM   4410  N  NE2 . GLN B 1 82  ? 164.975 191.967 171.567 1.00 49.78  ? 82  GLN B NE2 1 
ATOM   4411  N  N   . SER B 1 83  ? 169.576 195.783 170.720 1.00 50.79  ? 83  SER B N   1 
ATOM   4412  C  CA  . SER B 1 83  ? 170.172 196.527 169.624 1.00 50.79  ? 83  SER B CA  1 
ATOM   4413  C  C   . SER B 1 83  ? 171.411 197.249 170.128 1.00 50.79  ? 83  SER B C   1 
ATOM   4414  O  O   . SER B 1 83  ? 171.335 198.033 171.077 1.00 50.79  ? 83  SER B O   1 
ATOM   4415  C  CB  . SER B 1 83  ? 169.180 197.530 169.036 1.00 50.79  ? 83  SER B CB  1 
ATOM   4416  O  OG  . SER B 1 83  ? 168.867 198.533 169.981 1.00 50.79  ? 83  SER B OG  1 
ATOM   4417  N  N   . CYS B 1 84  ? 172.550 196.986 169.484 1.00 57.43  ? 84  CYS B N   1 
ATOM   4418  C  CA  . CYS B 1 84  ? 173.819 197.540 169.942 1.00 57.43  ? 84  CYS B CA  1 
ATOM   4419  C  C   . CYS B 1 84  ? 173.878 199.057 169.805 1.00 57.43  ? 84  CYS B C   1 
ATOM   4420  O  O   . CYS B 1 84  ? 174.691 199.703 170.478 1.00 57.43  ? 84  CYS B O   1 
ATOM   4421  C  CB  . CYS B 1 84  ? 174.976 196.895 169.177 1.00 57.43  ? 84  CYS B CB  1 
ATOM   4422  S  SG  . CYS B 1 84  ? 176.627 197.418 169.702 1.00 57.43  ? 84  CYS B SG  1 
ATOM   4423  N  N   . PHE B 1 85  ? 173.033 199.642 168.952 1.00 52.79  ? 85  PHE B N   1 
ATOM   4424  C  CA  . PHE B 1 85  ? 173.006 201.094 168.808 1.00 52.79  ? 85  PHE B CA  1 
ATOM   4425  C  C   . PHE B 1 85  ? 172.644 201.768 170.125 1.00 52.79  ? 85  PHE B C   1 
ATOM   4426  O  O   . PHE B 1 85  ? 173.331 202.693 170.574 1.00 52.79  ? 85  PHE B O   1 
ATOM   4427  C  CB  . PHE B 1 85  ? 172.021 201.490 167.709 1.00 52.79  ? 85  PHE B CB  1 
ATOM   4428  C  CG  . PHE B 1 85  ? 171.920 202.972 167.486 1.00 52.79  ? 85  PHE B CG  1 
ATOM   4429  C  CD1 . PHE B 1 85  ? 172.912 203.656 166.807 1.00 52.79  ? 85  PHE B CD1 1 
ATOM   4430  C  CD2 . PHE B 1 85  ? 170.826 203.680 167.950 1.00 52.79  ? 85  PHE B CD2 1 
ATOM   4431  C  CE1 . PHE B 1 85  ? 172.814 205.020 166.600 1.00 52.79  ? 85  PHE B CE1 1 
ATOM   4432  C  CE2 . PHE B 1 85  ? 170.722 205.042 167.746 1.00 52.79  ? 85  PHE B CE2 1 
ATOM   4433  C  CZ  . PHE B 1 85  ? 171.716 205.713 167.071 1.00 52.79  ? 85  PHE B CZ  1 
ATOM   4434  N  N   . PHE B 1 86  ? 171.567 201.310 170.767 1.00 53.23  ? 86  PHE B N   1 
ATOM   4435  C  CA  . PHE B 1 86  ? 171.189 201.871 172.060 1.00 53.23  ? 86  PHE B CA  1 
ATOM   4436  C  C   . PHE B 1 86  ? 172.172 201.461 173.150 1.00 53.23  ? 86  PHE B C   1 
ATOM   4437  O  O   . PHE B 1 86  ? 172.333 202.173 174.148 1.00 53.23  ? 86  PHE B O   1 
ATOM   4438  C  CB  . PHE B 1 86  ? 169.769 201.447 172.427 1.00 53.23  ? 86  PHE B CB  1 
ATOM   4439  C  CG  . PHE B 1 86  ? 168.703 202.083 171.578 1.00 53.23  ? 86  PHE B CG  1 
ATOM   4440  C  CD1 . PHE B 1 86  ? 168.302 203.384 171.812 1.00 53.23  ? 86  PHE B CD1 1 
ATOM   4441  C  CD2 . PHE B 1 86  ? 168.087 201.373 170.565 1.00 53.23  ? 86  PHE B CD2 1 
ATOM   4442  C  CE1 . PHE B 1 86  ? 167.320 203.970 171.042 1.00 53.23  ? 86  PHE B CE1 1 
ATOM   4443  C  CE2 . PHE B 1 86  ? 167.104 201.953 169.794 1.00 53.23  ? 86  PHE B CE2 1 
ATOM   4444  C  CZ  . PHE B 1 86  ? 166.720 203.253 170.033 1.00 53.23  ? 86  PHE B CZ  1 
ATOM   4445  N  N   . ARG B 1 87  ? 172.835 200.314 172.982 1.00 58.57  ? 87  ARG B N   1 
ATOM   4446  C  CA  . ARG B 1 87  ? 173.866 199.922 173.937 1.00 58.57  ? 87  ARG B CA  1 
ATOM   4447  C  C   . ARG B 1 87  ? 175.032 200.898 173.909 1.00 58.57  ? 87  ARG B C   1 
ATOM   4448  O  O   . ARG B 1 87  ? 175.645 201.178 174.945 1.00 58.57  ? 87  ARG B O   1 
ATOM   4449  C  CB  . ARG B 1 87  ? 174.358 198.504 173.648 1.00 58.57  ? 87  ARG B CB  1 
ATOM   4450  C  CG  . ARG B 1 87  ? 175.374 197.998 174.664 1.00 58.57  ? 87  ARG B CG  1 
ATOM   4451  C  CD  . ARG B 1 87  ? 175.888 196.601 174.341 1.00 58.57  ? 87  ARG B CD  1 
ATOM   4452  N  NE  . ARG B 1 87  ? 174.848 195.579 174.418 1.00 58.57  ? 87  ARG B NE  1 
ATOM   4453  C  CZ  . ARG B 1 87  ? 174.432 194.857 173.383 1.00 58.57  ? 87  ARG B CZ  1 
ATOM   4454  N  NH1 . ARG B 1 87  ? 174.974 195.034 172.187 1.00 58.57  ? 87  ARG B NH1 1 
ATOM   4455  N  NH2 . ARG B 1 87  ? 173.481 193.948 173.545 1.00 58.57  ? 87  ARG B NH2 1 
ATOM   4456  N  N   . SER B 1 88  ? 175.355 201.429 172.728 1.00 61.25  ? 88  SER B N   1 
ATOM   4457  C  CA  . SER B 1 88  ? 176.453 202.384 172.627 1.00 61.25  ? 88  SER B CA  1 
ATOM   4458  C  C   . SER B 1 88  ? 175.977 203.804 172.901 1.00 61.25  ? 88  SER B C   1 
ATOM   4459  O  O   . SER B 1 88  ? 176.783 204.685 173.219 1.00 61.25  ? 88  SER B O   1 
ATOM   4460  C  CB  . SER B 1 88  ? 177.105 202.291 171.249 1.00 61.25  ? 88  SER B CB  1 
ATOM   4461  O  OG  . SER B 1 88  ? 177.704 201.022 171.060 1.00 61.25  ? 88  SER B OG  1 
ATOM   4462  N  N   . MET B 1 89  ? 174.672 204.048 172.781 1.00 60.89  ? 89  MET B N   1 
ATOM   4463  C  CA  . MET B 1 89  ? 174.161 205.388 173.049 1.00 60.89  ? 89  MET B CA  1 
ATOM   4464  C  C   . MET B 1 89  ? 173.933 205.597 174.540 1.00 60.89  ? 89  MET B C   1 
ATOM   4465  O  O   . MET B 1 89  ? 174.045 206.722 175.041 1.00 60.89  ? 89  MET B O   1 
ATOM   4466  C  CB  . MET B 1 89  ? 172.871 205.626 172.267 1.00 60.89  ? 89  MET B CB  1 
ATOM   4467  C  CG  . MET B 1 89  ? 172.345 207.044 172.367 1.00 60.89  ? 89  MET B CG  1 
ATOM   4468  S  SD  . MET B 1 89  ? 170.821 207.313 171.446 1.00 60.89  ? 89  MET B SD  1 
ATOM   4469  C  CE  . MET B 1 89  ? 169.635 206.509 172.514 1.00 60.89  ? 89  MET B CE  1 
ATOM   4470  N  N   . PHE B 1 90  ? 173.618 204.522 175.264 1.00 59.81  ? 90  PHE B N   1 
ATOM   4471  C  CA  . PHE B 1 90  ? 173.360 204.636 176.696 1.00 59.81  ? 90  PHE B CA  1 
ATOM   4472  C  C   . PHE B 1 90  ? 174.657 204.649 177.493 1.00 59.81  ? 90  PHE B C   1 
ATOM   4473  O  O   . PHE B 1 90  ? 174.994 205.658 178.123 1.00 59.81  ? 90  PHE B O   1 
ATOM   4474  C  CB  . PHE B 1 90  ? 172.461 203.488 177.151 1.00 59.81  ? 90  PHE B CB  1 
ATOM   4475  C  CG  . PHE B 1 90  ? 171.054 203.584 176.641 1.00 59.81  ? 90  PHE B CG  1 
ATOM   4476  C  CD1 . PHE B 1 90  ? 170.537 204.797 176.228 1.00 59.81  ? 90  PHE B CD1 1 
ATOM   4477  C  CD2 . PHE B 1 90  ? 170.261 202.457 176.543 1.00 59.81  ? 90  PHE B CD2 1 
ATOM   4478  C  CE1 . PHE B 1 90  ? 169.246 204.887 175.751 1.00 59.81  ? 90  PHE B CE1 1 
ATOM   4479  C  CE2 . PHE B 1 90  ? 168.972 202.542 176.065 1.00 59.81  ? 90  PHE B CE2 1 
ATOM   4480  C  CZ  . PHE B 1 90  ? 168.465 203.759 175.667 1.00 59.81  ? 90  PHE B CZ  1 
ATOM   4481  N  N   . THR B 1 91  ? 175.394 203.542 177.482 1.00 70.40  ? 91  THR B N   1 
ATOM   4482  C  CA  . THR B 1 91  ? 176.673 203.443 178.171 1.00 70.40  ? 91  THR B CA  1 
ATOM   4483  C  C   . THR B 1 91  ? 177.763 204.275 177.508 1.00 70.40  ? 91  THR B C   1 
ATOM   4484  O  O   . THR B 1 91  ? 178.704 203.704 176.946 1.00 70.40  ? 91  THR B O   1 
ATOM   4485  C  CB  . THR B 1 91  ? 177.121 201.983 178.244 1.00 70.40  ? 91  THR B CB  1 
ATOM   4486  O  OG1 . THR B 1 91  ? 177.332 201.480 176.920 1.00 70.40  ? 91  THR B OG1 1 
ATOM   4487  C  CG2 . THR B 1 91  ? 176.060 201.144 178.927 1.00 70.40  ? 91  THR B CG2 1 
ATOM   4488  N  N   . SER B 1 92  ? 177.665 205.599 177.566 1.00 87.90  ? 92  SER B N   1 
ATOM   4489  C  CA  . SER B 1 92  ? 178.609 206.445 176.857 1.00 87.90  ? 92  SER B CA  1 
ATOM   4490  C  C   . SER B 1 92  ? 179.268 207.443 177.804 1.00 87.90  ? 92  SER B C   1 
ATOM   4491  O  O   . SER B 1 92  ? 178.837 207.646 178.943 1.00 87.90  ? 92  SER B O   1 
ATOM   4492  C  CB  . SER B 1 92  ? 177.907 207.194 175.726 1.00 87.90  ? 92  SER B CB  1 
ATOM   4493  O  OG  . SER B 1 92  ? 176.960 208.114 176.242 1.00 87.90  ? 92  SER B OG  1 
ATOM   4494  N  N   . ASN B 1 93  ? 180.336 208.068 177.313 1.00 98.51  ? 93  ASN B N   1 
ATOM   4495  C  CA  . ASN B 1 93  ? 181.001 209.150 178.026 1.00 98.51  ? 93  ASN B CA  1 
ATOM   4496  C  C   . ASN B 1 93  ? 180.402 210.512 177.709 1.00 98.51  ? 93  ASN B C   1 
ATOM   4497  O  O   . ASN B 1 93  ? 180.996 211.533 178.072 1.00 98.51  ? 93  ASN B O   1 
ATOM   4498  C  CB  . ASN B 1 93  ? 182.496 209.156 177.695 1.00 98.51  ? 93  ASN B CB  1 
ATOM   4499  C  CG  . ASN B 1 93  ? 183.229 207.971 178.288 1.00 98.51  ? 93  ASN B CG  1 
ATOM   4500  O  OD1 . ASN B 1 93  ? 182.990 207.588 179.432 1.00 98.51  ? 93  ASN B OD1 1 
ATOM   4501  N  ND2 . ASN B 1 93  ? 184.129 207.382 177.509 1.00 98.51  ? 93  ASN B ND2 1 
ATOM   4502  N  N   . LEU B 1 94  ? 179.248 210.551 177.047 1.00 107.83 ? 94  LEU B N   1 
ATOM   4503  C  CA  . LEU B 1 94  ? 178.636 211.815 176.668 1.00 107.83 ? 94  LEU B CA  1 
ATOM   4504  C  C   . LEU B 1 94  ? 177.974 212.475 177.870 1.00 107.83 ? 94  LEU B C   1 
ATOM   4505  O  O   . LEU B 1 94  ? 178.044 211.973 178.996 1.00 107.83 ? 94  LEU B O   1 
ATOM   4506  C  CB  . LEU B 1 94  ? 177.604 211.589 175.564 1.00 107.83 ? 94  LEU B CB  1 
ATOM   4507  C  CG  . LEU B 1 94  ? 178.132 211.074 174.223 1.00 107.83 ? 94  LEU B CG  1 
ATOM   4508  C  CD1 . LEU B 1 94  ? 176.981 210.746 173.285 1.00 107.83 ? 94  LEU B CD1 1 
ATOM   4509  C  CD2 . LEU B 1 94  ? 179.070 212.088 173.591 1.00 107.83 ? 94  LEU B CD2 1 
ATOM   4510  N  N   . LYS B 1 95  ? 177.325 213.615 177.624 1.00 117.34 ? 95  LYS B N   1 
ATOM   4511  C  CA  . LYS B 1 95  ? 176.581 214.292 178.679 1.00 117.34 ? 95  LYS B CA  1 
ATOM   4512  C  C   . LYS B 1 95  ? 175.167 213.748 178.826 1.00 117.34 ? 95  LYS B C   1 
ATOM   4513  O  O   . LYS B 1 95  ? 174.590 213.844 179.914 1.00 117.34 ? 95  LYS B O   1 
ATOM   4514  C  CB  . LYS B 1 95  ? 176.528 215.796 178.409 1.00 117.34 ? 95  LYS B CB  1 
ATOM   4515  C  CG  . LYS B 1 95  ? 177.865 216.506 178.531 1.00 117.34 ? 95  LYS B CG  1 
ATOM   4516  C  CD  . LYS B 1 95  ? 177.710 217.999 178.290 1.00 117.34 ? 95  LYS B CD  1 
ATOM   4517  C  CE  . LYS B 1 95  ? 179.042 218.722 178.392 1.00 117.34 ? 95  LYS B CE  1 
ATOM   4518  N  NZ  . LYS B 1 95  ? 178.897 220.184 178.148 1.00 117.34 ? 95  LYS B NZ  1 
ATOM   4519  N  N   . GLU B 1 96  ? 174.601 213.178 177.760 1.00 118.80 ? 96  GLU B N   1 
ATOM   4520  C  CA  . GLU B 1 96  ? 173.233 212.675 177.827 1.00 118.80 ? 96  GLU B CA  1 
ATOM   4521  C  C   . GLU B 1 96  ? 173.188 211.216 178.262 1.00 118.80 ? 96  GLU B C   1 
ATOM   4522  O  O   . GLU B 1 96  ? 172.262 210.488 177.886 1.00 118.80 ? 96  GLU B O   1 
ATOM   4523  C  CB  . GLU B 1 96  ? 172.543 212.849 176.474 1.00 118.80 ? 96  GLU B CB  1 
ATOM   4524  C  CG  . GLU B 1 96  ? 172.306 214.299 176.075 1.00 118.80 ? 96  GLU B CG  1 
ATOM   4525  C  CD  . GLU B 1 96  ? 173.525 214.942 175.439 1.00 118.80 ? 96  GLU B CD  1 
ATOM   4526  O  OE1 . GLU B 1 96  ? 174.540 214.240 175.249 1.00 118.80 ? 96  GLU B OE1 1 
ATOM   4527  O  OE2 . GLU B 1 96  ? 173.468 216.151 175.130 1.00 118.80 ? 96  GLU B OE2 1 
ATOM   4528  N  N   . ALA B 1 97  ? 174.171 210.771 179.047 1.00 113.99 ? 97  ALA B N   1 
ATOM   4529  C  CA  . ALA B 1 97  ? 174.165 209.401 179.543 1.00 113.99 ? 97  ALA B CA  1 
ATOM   4530  C  C   . ALA B 1 97  ? 173.253 209.230 180.750 1.00 113.99 ? 97  ALA B C   1 
ATOM   4531  O  O   . ALA B 1 97  ? 172.393 208.342 180.740 1.00 113.99 ? 97  ALA B O   1 
ATOM   4532  C  CB  . ALA B 1 97  ? 175.586 208.962 179.899 1.00 113.99 ? 97  ALA B CB  1 
ATOM   4533  N  N   . HIS B 1 98  ? 173.418 210.054 181.783 1.00 114.51 ? 98  HIS B N   1 
ATOM   4534  C  CA  . HIS B 1 98  ? 172.581 209.972 182.972 1.00 114.51 ? 98  HIS B CA  1 
ATOM   4535  C  C   . HIS B 1 98  ? 171.702 211.199 183.173 1.00 114.51 ? 98  HIS B C   1 
ATOM   4536  O  O   . HIS B 1 98  ? 171.213 211.411 184.288 1.00 114.51 ? 98  HIS B O   1 
ATOM   4537  C  CB  . HIS B 1 98  ? 173.448 209.744 184.212 1.00 114.51 ? 98  HIS B CB  1 
ATOM   4538  C  CG  . HIS B 1 98  ? 174.078 208.387 184.265 1.00 114.51 ? 98  HIS B CG  1 
ATOM   4539  N  ND1 . HIS B 1 98  ? 175.297 208.107 183.686 1.00 114.51 ? 98  HIS B ND1 1 
ATOM   4540  C  CD2 . HIS B 1 98  ? 173.655 207.230 184.827 1.00 114.51 ? 98  HIS B CD2 1 
ATOM   4541  C  CE1 . HIS B 1 98  ? 175.598 206.837 183.889 1.00 114.51 ? 98  HIS B CE1 1 
ATOM   4542  N  NE2 . HIS B 1 98  ? 174.618 206.282 184.580 1.00 114.51 ? 98  HIS B NE2 1 
ATOM   4543  N  N   . ASN B 1 99  ? 171.495 212.010 182.139 1.00 112.26 ? 99  ASN B N   1 
ATOM   4544  C  CA  . ASN B 1 99  ? 170.502 213.068 182.221 1.00 112.26 ? 99  ASN B CA  1 
ATOM   4545  C  C   . ASN B 1 99  ? 169.100 212.465 182.215 1.00 112.26 ? 99  ASN B C   1 
ATOM   4546  O  O   . ASN B 1 99  ? 168.633 211.903 183.210 1.00 112.26 ? 99  ASN B O   1 
ATOM   4547  C  CB  . ASN B 1 99  ? 170.664 214.055 181.065 1.00 112.26 ? 99  ASN B CB  1 
ATOM   4548  C  CG  . ASN B 1 99  ? 171.918 214.897 181.189 1.00 112.26 ? 99  ASN B CG  1 
ATOM   4549  O  OD1 . ASN B 1 99  ? 172.271 215.349 182.279 1.00 112.26 ? 99  ASN B OD1 1 
ATOM   4550  N  ND2 . ASN B 1 99  ? 172.596 215.117 180.070 1.00 112.26 ? 99  ASN B ND2 1 
ATOM   4551  N  N   . ARG B 1 100 ? 168.429 212.580 181.064 1.00 94.95  ? 100 ARG B N   1 
ATOM   4552  C  CA  . ARG B 1 100 ? 167.161 211.881 180.877 1.00 94.95  ? 100 ARG B CA  1 
ATOM   4553  C  C   . ARG B 1 100 ? 166.730 211.851 179.416 1.00 94.95  ? 100 ARG B C   1 
ATOM   4554  O  O   . ARG B 1 100 ? 166.924 210.838 178.736 1.00 94.95  ? 100 ARG B O   1 
ATOM   4555  C  CB  . ARG B 1 100 ? 166.055 212.517 181.721 1.00 94.95  ? 100 ARG B CB  1 
ATOM   4556  C  CG  . ARG B 1 100 ? 164.721 211.793 181.598 1.00 94.95  ? 100 ARG B CG  1 
ATOM   4557  C  CD  . ARG B 1 100 ? 163.656 212.385 182.505 1.00 94.95  ? 100 ARG B CD  1 
ATOM   4558  N  NE  . ARG B 1 100 ? 163.922 212.119 183.915 1.00 94.95  ? 100 ARG B NE  1 
ATOM   4559  C  CZ  . ARG B 1 100 ? 163.223 212.644 184.916 1.00 94.95  ? 100 ARG B CZ  1 
ATOM   4560  N  NH1 . ARG B 1 100 ? 162.213 213.465 184.663 1.00 94.95  ? 100 ARG B NH1 1 
ATOM   4561  N  NH2 . ARG B 1 100 ? 163.532 212.346 186.171 1.00 94.95  ? 100 ARG B NH2 1 
ATOM   4562  N  N   . VAL B 1 101 ? 166.151 212.944 178.921 1.00 81.78  ? 101 VAL B N   1 
ATOM   4563  C  CA  . VAL B 1 101 ? 165.423 212.963 177.657 1.00 81.78  ? 101 VAL B CA  1 
ATOM   4564  C  C   . VAL B 1 101 ? 166.399 212.751 176.508 1.00 81.78  ? 101 VAL B C   1 
ATOM   4565  O  O   . VAL B 1 101 ? 167.518 213.278 176.527 1.00 81.78  ? 101 VAL B O   1 
ATOM   4566  C  CB  . VAL B 1 101 ? 164.627 214.272 177.484 1.00 81.78  ? 101 VAL B CB  1 
ATOM   4567  C  CG1 . VAL B 1 101 ? 165.556 215.475 177.405 1.00 81.78  ? 101 VAL B CG1 1 
ATOM   4568  C  CG2 . VAL B 1 101 ? 163.725 214.197 176.260 1.00 81.78  ? 101 VAL B CG2 1 
ATOM   4569  N  N   . ILE B 1 102 ? 165.982 211.955 175.528 1.00 75.35  ? 102 ILE B N   1 
ATOM   4570  C  CA  . ILE B 1 102 ? 166.722 211.754 174.290 1.00 75.35  ? 102 ILE B CA  1 
ATOM   4571  C  C   . ILE B 1 102 ? 165.815 212.151 173.135 1.00 75.35  ? 102 ILE B C   1 
ATOM   4572  O  O   . ILE B 1 102 ? 164.612 211.871 173.160 1.00 75.35  ? 102 ILE B O   1 
ATOM   4573  C  CB  . ILE B 1 102 ? 167.199 210.295 174.138 1.00 75.35  ? 102 ILE B CB  1 
ATOM   4574  C  CG1 . ILE B 1 102 ? 168.086 209.899 175.315 1.00 75.35  ? 102 ILE B CG1 1 
ATOM   4575  C  CG2 . ILE B 1 102 ? 167.961 210.107 172.838 1.00 75.35  ? 102 ILE B CG2 1 
ATOM   4576  C  CD1 . ILE B 1 102 ? 169.350 210.713 175.416 1.00 75.35  ? 102 ILE B CD1 1 
ATOM   4577  N  N   . VAL B 1 103 ? 166.383 212.812 172.132 1.00 72.37  ? 103 VAL B N   1 
ATOM   4578  C  CA  . VAL B 1 103 ? 165.634 213.274 170.969 1.00 72.37  ? 103 VAL B CA  1 
ATOM   4579  C  C   . VAL B 1 103 ? 166.213 212.626 169.717 1.00 72.37  ? 103 VAL B C   1 
ATOM   4580  O  O   . VAL B 1 103 ? 167.261 213.047 169.211 1.00 72.37  ? 103 VAL B O   1 
ATOM   4581  C  CB  . VAL B 1 103 ? 165.629 214.811 170.878 1.00 72.37  ? 103 VAL B CB  1 
ATOM   4582  C  CG1 . VAL B 1 103 ? 164.742 215.386 171.968 1.00 72.37  ? 103 VAL B CG1 1 
ATOM   4583  C  CG2 . VAL B 1 103 ? 167.035 215.373 171.047 1.00 72.37  ? 103 VAL B CG2 1 
ATOM   4584  N  N   . LEU B 1 104 ? 165.538 211.591 169.227 1.00 64.82  ? 104 LEU B N   1 
ATOM   4585  C  CA  . LEU B 1 104 ? 165.920 210.921 167.993 1.00 64.82  ? 104 LEU B CA  1 
ATOM   4586  C  C   . LEU B 1 104 ? 165.487 211.779 166.813 1.00 64.82  ? 104 LEU B C   1 
ATOM   4587  O  O   . LEU B 1 104 ? 164.569 212.595 166.939 1.00 64.82  ? 104 LEU B O   1 
ATOM   4588  C  CB  . LEU B 1 104 ? 165.295 209.529 167.906 1.00 64.82  ? 104 LEU B CB  1 
ATOM   4589  C  CG  . LEU B 1 104 ? 165.785 208.523 168.948 1.00 64.82  ? 104 LEU B CG  1 
ATOM   4590  C  CD1 . LEU B 1 104 ? 165.038 207.212 168.817 1.00 64.82  ? 104 LEU B CD1 1 
ATOM   4591  C  CD2 . LEU B 1 104 ? 167.282 208.307 168.823 1.00 64.82  ? 104 LEU B CD2 1 
ATOM   4592  N  N   . GLN B 1 105 ? 166.147 211.595 165.670 1.00 67.23  ? 105 GLN B N   1 
ATOM   4593  C  CA  . GLN B 1 105 ? 165.932 212.497 164.543 1.00 67.23  ? 105 GLN B CA  1 
ATOM   4594  C  C   . GLN B 1 105 ? 165.117 211.842 163.433 1.00 67.23  ? 105 GLN B C   1 
ATOM   4595  O  O   . GLN B 1 105 ? 163.898 211.685 163.551 1.00 67.23  ? 105 GLN B O   1 
ATOM   4596  C  CB  . GLN B 1 105 ? 167.279 212.986 164.004 1.00 67.23  ? 105 GLN B CB  1 
ATOM   4597  C  CG  . GLN B 1 105 ? 168.059 213.844 164.982 1.00 67.23  ? 105 GLN B CG  1 
ATOM   4598  C  CD  . GLN B 1 105 ? 167.367 215.161 165.278 1.00 67.23  ? 105 GLN B CD  1 
ATOM   4599  O  OE1 . GLN B 1 105 ? 166.778 215.779 164.392 1.00 67.23  ? 105 GLN B OE1 1 
ATOM   4600  N  NE2 . GLN B 1 105 ? 167.435 215.597 166.530 1.00 67.23  ? 105 GLN B NE2 1 
ATOM   4601  N  N   . ASP B 1 106 ? 165.781 211.459 162.345 1.00 66.98  ? 106 ASP B N   1 
ATOM   4602  C  CA  . ASP B 1 106 ? 165.135 211.042 161.101 1.00 66.98  ? 106 ASP B CA  1 
ATOM   4603  C  C   . ASP B 1 106 ? 164.361 209.742 161.315 1.00 66.98  ? 106 ASP B C   1 
ATOM   4604  O  O   . ASP B 1 106 ? 164.728 208.680 160.813 1.00 66.98  ? 106 ASP B O   1 
ATOM   4605  C  CB  . ASP B 1 106 ? 166.191 210.917 159.981 1.00 66.98  ? 106 ASP B CB  1 
ATOM   4606  C  CG  . ASP B 1 106 ? 167.331 209.984 160.350 1.00 66.98  ? 106 ASP B CG  1 
ATOM   4607  O  OD1 . ASP B 1 106 ? 167.344 209.475 161.490 1.00 66.98  ? 106 ASP B OD1 1 
ATOM   4608  O  OD2 . ASP B 1 106 ? 168.220 209.765 159.500 1.00 66.98  ? 106 ASP B OD2 1 
ATOM   4609  N  N   . VAL B 1 107 ? 163.258 209.843 162.057 1.00 61.43  ? 107 VAL B N   1 
ATOM   4610  C  CA  . VAL B 1 107 ? 162.324 208.736 162.224 1.00 61.43  ? 107 VAL B CA  1 
ATOM   4611  C  C   . VAL B 1 107 ? 161.018 209.317 162.743 1.00 61.43  ? 107 VAL B C   1 
ATOM   4612  O  O   . VAL B 1 107 ? 161.015 210.275 163.519 1.00 61.43  ? 107 VAL B O   1 
ATOM   4613  C  CB  . VAL B 1 107 ? 162.896 207.642 163.164 1.00 61.43  ? 107 VAL B CB  1 
ATOM   4614  C  CG1 . VAL B 1 107 ? 163.071 208.170 164.576 1.00 61.43  ? 107 VAL B CG1 1 
ATOM   4615  C  CG2 . VAL B 1 107 ? 162.014 206.408 163.153 1.00 61.43  ? 107 VAL B CG2 1 
ATOM   4616  N  N   . SER B 1 108 ? 159.904 208.753 162.290 1.00 60.14  ? 108 SER B N   1 
ATOM   4617  C  CA  . SER B 1 108 ? 158.590 209.262 162.650 1.00 60.14  ? 108 SER B CA  1 
ATOM   4618  C  C   . SER B 1 108 ? 158.100 208.621 163.941 1.00 60.14  ? 108 SER B C   1 
ATOM   4619  O  O   . SER B 1 108 ? 158.672 207.645 164.430 1.00 60.14  ? 108 SER B O   1 
ATOM   4620  C  CB  . SER B 1 108 ? 157.585 209.003 161.529 1.00 60.14  ? 108 SER B CB  1 
ATOM   4621  O  OG  . SER B 1 108 ? 157.352 207.616 161.366 1.00 60.14  ? 108 SER B OG  1 
ATOM   4622  N  N   . GLU B 1 109 ? 157.026 209.187 164.496 1.00 62.70  ? 109 GLU B N   1 
ATOM   4623  C  CA  . GLU B 1 109 ? 156.429 208.612 165.694 1.00 62.70  ? 109 GLU B CA  1 
ATOM   4624  C  C   . GLU B 1 109 ? 155.437 207.506 165.366 1.00 62.70  ? 109 GLU B C   1 
ATOM   4625  O  O   . GLU B 1 109 ? 154.759 207.010 166.272 1.00 62.70  ? 109 GLU B O   1 
ATOM   4626  C  CB  . GLU B 1 109 ? 155.745 209.700 166.525 1.00 62.70  ? 109 GLU B CB  1 
ATOM   4627  C  CG  . GLU B 1 109 ? 154.484 210.282 165.906 1.00 62.70  ? 109 GLU B CG  1 
ATOM   4628  C  CD  . GLU B 1 109 ? 154.769 211.438 164.968 1.00 62.70  ? 109 GLU B CD  1 
ATOM   4629  O  OE1 . GLU B 1 109 ? 155.934 211.597 164.553 1.00 62.70  ? 109 GLU B OE1 1 
ATOM   4630  O  OE2 . GLU B 1 109 ? 153.828 212.193 164.650 1.00 62.70  ? 109 GLU B OE2 1 
ATOM   4631  N  N   . SER B 1 110 ? 155.333 207.116 164.095 1.00 56.30  ? 110 SER B N   1 
ATOM   4632  C  CA  . SER B 1 110 ? 154.471 206.002 163.721 1.00 56.30  ? 110 SER B CA  1 
ATOM   4633  C  C   . SER B 1 110 ? 155.276 204.783 163.302 1.00 56.30  ? 110 SER B C   1 
ATOM   4634  O  O   . SER B 1 110 ? 154.700 203.717 163.062 1.00 56.30  ? 110 SER B O   1 
ATOM   4635  C  CB  . SER B 1 110 ? 153.527 206.420 162.594 1.00 56.30  ? 110 SER B CB  1 
ATOM   4636  O  OG  . SER B 1 110 ? 152.647 207.443 163.024 1.00 56.30  ? 110 SER B OG  1 
ATOM   4637  N  N   . VAL B 1 111 ? 156.596 204.925 163.194 1.00 52.83  ? 111 VAL B N   1 
ATOM   4638  C  CA  . VAL B 1 111 ? 157.462 203.777 162.950 1.00 52.83  ? 111 VAL B CA  1 
ATOM   4639  C  C   . VAL B 1 111 ? 158.149 203.346 164.237 1.00 52.83  ? 111 VAL B C   1 
ATOM   4640  O  O   . VAL B 1 111 ? 158.283 202.147 164.515 1.00 52.83  ? 111 VAL B O   1 
ATOM   4641  C  CB  . VAL B 1 111 ? 158.480 204.109 161.847 1.00 52.83  ? 111 VAL B CB  1 
ATOM   4642  C  CG1 . VAL B 1 111 ? 159.517 203.013 161.738 1.00 52.83  ? 111 VAL B CG1 1 
ATOM   4643  C  CG2 . VAL B 1 111 ? 157.770 204.295 160.521 1.00 52.83  ? 111 VAL B CG2 1 
ATOM   4644  N  N   . PHE B 1 112 ? 158.577 204.311 165.052 1.00 50.94  ? 112 PHE B N   1 
ATOM   4645  C  CA  . PHE B 1 112 ? 159.239 203.967 166.303 1.00 50.94  ? 112 PHE B CA  1 
ATOM   4646  C  C   . PHE B 1 112 ? 158.280 203.263 167.252 1.00 50.94  ? 112 PHE B C   1 
ATOM   4647  O  O   . PHE B 1 112 ? 158.717 202.539 168.152 1.00 50.94  ? 112 PHE B O   1 
ATOM   4648  C  CB  . PHE B 1 112 ? 159.816 205.224 166.950 1.00 50.94  ? 112 PHE B CB  1 
ATOM   4649  C  CG  . PHE B 1 112 ? 160.779 204.942 168.065 1.00 50.94  ? 112 PHE B CG  1 
ATOM   4650  C  CD1 . PHE B 1 112 ? 162.066 204.525 167.798 1.00 50.94  ? 112 PHE B CD1 1 
ATOM   4651  C  CD2 . PHE B 1 112 ? 160.401 205.092 169.379 1.00 50.94  ? 112 PHE B CD2 1 
ATOM   4652  C  CE1 . PHE B 1 112 ? 162.955 204.260 168.825 1.00 50.94  ? 112 PHE B CE1 1 
ATOM   4653  C  CE2 . PHE B 1 112 ? 161.289 204.826 170.404 1.00 50.94  ? 112 PHE B CE2 1 
ATOM   4654  C  CZ  . PHE B 1 112 ? 162.564 204.414 170.125 1.00 50.94  ? 112 PHE B CZ  1 
ATOM   4655  N  N   . GLN B 1 113 ? 156.974 203.466 167.073 1.00 50.08  ? 113 GLN B N   1 
ATOM   4656  C  CA  . GLN B 1 113 ? 155.994 202.697 167.829 1.00 50.08  ? 113 GLN B CA  1 
ATOM   4657  C  C   . GLN B 1 113 ? 155.989 201.234 167.409 1.00 50.08  ? 113 GLN B C   1 
ATOM   4658  O  O   . GLN B 1 113 ? 155.815 200.350 168.254 1.00 50.08  ? 113 GLN B O   1 
ATOM   4659  C  CB  . GLN B 1 113 ? 154.605 203.308 167.657 1.00 50.08  ? 113 GLN B CB  1 
ATOM   4660  C  CG  . GLN B 1 113 ? 153.504 202.578 168.404 1.00 50.08  ? 113 GLN B CG  1 
ATOM   4661  C  CD  . GLN B 1 113 ? 153.718 202.568 169.903 1.00 50.08  ? 113 GLN B CD  1 
ATOM   4662  O  OE1 . GLN B 1 113 ? 154.120 201.556 170.477 1.00 50.08  ? 113 GLN B OE1 1 
ATOM   4663  N  NE2 . GLN B 1 113 ? 153.446 203.695 170.548 1.00 50.08  ? 113 GLN B NE2 1 
ATOM   4664  N  N   . LEU B 1 114 ? 156.166 200.956 166.114 1.00 47.09  ? 114 LEU B N   1 
ATOM   4665  C  CA  . LEU B 1 114 ? 156.360 199.577 165.680 1.00 47.09  ? 114 LEU B CA  1 
ATOM   4666  C  C   . LEU B 1 114 ? 157.683 199.018 166.181 1.00 47.09  ? 114 LEU B C   1 
ATOM   4667  O  O   . LEU B 1 114 ? 157.786 197.814 166.445 1.00 47.09  ? 114 LEU B O   1 
ATOM   4668  C  CB  . LEU B 1 114 ? 156.289 199.473 164.156 1.00 47.09  ? 114 LEU B CB  1 
ATOM   4669  C  CG  . LEU B 1 114 ? 154.909 199.342 163.509 1.00 47.09  ? 114 LEU B CG  1 
ATOM   4670  C  CD1 . LEU B 1 114 ? 154.121 200.632 163.601 1.00 47.09  ? 114 LEU B CD1 1 
ATOM   4671  C  CD2 . LEU B 1 114 ? 155.048 198.905 162.061 1.00 47.09  ? 114 LEU B CD2 1 
ATOM   4672  N  N   . LEU B 1 115 ? 158.701 199.868 166.324 1.00 46.45  ? 115 LEU B N   1 
ATOM   4673  C  CA  . LEU B 1 115 ? 159.969 199.391 166.864 1.00 46.45  ? 115 LEU B CA  1 
ATOM   4674  C  C   . LEU B 1 115 ? 159.851 199.062 168.346 1.00 46.45  ? 115 LEU B C   1 
ATOM   4675  O  O   . LEU B 1 115 ? 160.505 198.135 168.832 1.00 46.45  ? 115 LEU B O   1 
ATOM   4676  C  CB  . LEU B 1 115 ? 161.065 200.425 166.631 1.00 46.45  ? 115 LEU B CB  1 
ATOM   4677  C  CG  . LEU B 1 115 ? 161.431 200.694 165.175 1.00 46.45  ? 115 LEU B CG  1 
ATOM   4678  C  CD1 . LEU B 1 115 ? 162.441 201.807 165.117 1.00 46.45  ? 115 LEU B CD1 1 
ATOM   4679  C  CD2 . LEU B 1 115 ? 161.972 199.447 164.511 1.00 46.45  ? 115 LEU B CD2 1 
ATOM   4680  N  N   . VAL B 1 116 ? 159.034 199.815 169.084 1.00 46.59  ? 116 VAL B N   1 
ATOM   4681  C  CA  . VAL B 1 116 ? 158.783 199.475 170.481 1.00 46.59  ? 116 VAL B CA  1 
ATOM   4682  C  C   . VAL B 1 116 ? 157.945 198.207 170.574 1.00 46.59  ? 116 VAL B C   1 
ATOM   4683  O  O   . VAL B 1 116 ? 158.226 197.315 171.386 1.00 46.59  ? 116 VAL B O   1 
ATOM   4684  C  CB  . VAL B 1 116 ? 158.115 200.655 171.209 1.00 46.59  ? 116 VAL B CB  1 
ATOM   4685  C  CG1 . VAL B 1 116 ? 157.663 200.240 172.593 1.00 46.59  ? 116 VAL B CG1 1 
ATOM   4686  C  CG2 . VAL B 1 116 ? 159.080 201.817 171.307 1.00 46.59  ? 116 VAL B CG2 1 
ATOM   4687  N  N   . ASP B 1 117 ? 156.917 198.096 169.730 1.00 49.19  ? 117 ASP B N   1 
ATOM   4688  C  CA  . ASP B 1 117 ? 156.095 196.891 169.720 1.00 49.19  ? 117 ASP B CA  1 
ATOM   4689  C  C   . ASP B 1 117 ? 156.905 195.674 169.295 1.00 49.19  ? 117 ASP B C   1 
ATOM   4690  O  O   . ASP B 1 117 ? 156.505 194.534 169.550 1.00 49.19  ? 117 ASP B O   1 
ATOM   4691  C  CB  . ASP B 1 117 ? 154.891 197.079 168.799 1.00 49.19  ? 117 ASP B CB  1 
ATOM   4692  C  CG  . ASP B 1 117 ? 153.882 198.070 169.347 1.00 49.19  ? 117 ASP B CG  1 
ATOM   4693  O  OD1 . ASP B 1 117 ? 153.780 198.199 170.584 1.00 49.19  ? 117 ASP B OD1 1 
ATOM   4694  O  OD2 . ASP B 1 117 ? 153.187 198.720 168.538 1.00 49.19  ? 117 ASP B OD2 1 
ATOM   4695  N  N   . TYR B 1 118 ? 158.043 195.895 168.637 1.00 43.90  ? 118 TYR B N   1 
ATOM   4696  C  CA  . TYR B 1 118 ? 158.902 194.774 168.273 1.00 43.90  ? 118 TYR B CA  1 
ATOM   4697  C  C   . TYR B 1 118 ? 159.904 194.456 169.373 1.00 43.90  ? 118 TYR B C   1 
ATOM   4698  O  O   . TYR B 1 118 ? 160.153 193.283 169.672 1.00 43.90  ? 118 TYR B O   1 
ATOM   4699  C  CB  . TYR B 1 118 ? 159.637 195.067 166.969 1.00 43.90  ? 118 TYR B CB  1 
ATOM   4700  C  CG  . TYR B 1 118 ? 160.571 193.955 166.577 1.00 43.90  ? 118 TYR B CG  1 
ATOM   4701  C  CD1 . TYR B 1 118 ? 160.085 192.773 166.048 1.00 43.90  ? 118 TYR B CD1 1 
ATOM   4702  C  CD2 . TYR B 1 118 ? 161.937 194.078 166.755 1.00 43.90  ? 118 TYR B CD2 1 
ATOM   4703  C  CE1 . TYR B 1 118 ? 160.934 191.750 165.696 1.00 43.90  ? 118 TYR B CE1 1 
ATOM   4704  C  CE2 . TYR B 1 118 ? 162.792 193.061 166.407 1.00 43.90  ? 118 TYR B CE2 1 
ATOM   4705  C  CZ  . TYR B 1 118 ? 162.285 191.900 165.879 1.00 43.90  ? 118 TYR B CZ  1 
ATOM   4706  O  OH  . TYR B 1 118 ? 163.137 190.883 165.530 1.00 43.90  ? 118 TYR B OH  1 
ATOM   4707  N  N   . ILE B 1 119 ? 160.502 195.481 169.978 1.00 45.25  ? 119 ILE B N   1 
ATOM   4708  C  CA  . ILE B 1 119 ? 161.533 195.245 170.983 1.00 45.25  ? 119 ILE B CA  1 
ATOM   4709  C  C   . ILE B 1 119 ? 160.924 194.656 172.248 1.00 45.25  ? 119 ILE B C   1 
ATOM   4710  O  O   . ILE B 1 119 ? 161.454 193.697 172.819 1.00 45.25  ? 119 ILE B O   1 
ATOM   4711  C  CB  . ILE B 1 119 ? 162.313 196.538 171.278 1.00 45.25  ? 119 ILE B CB  1 
ATOM   4712  C  CG1 . ILE B 1 119 ? 163.125 196.964 170.059 1.00 45.25  ? 119 ILE B CG1 1 
ATOM   4713  C  CG2 . ILE B 1 119 ? 163.233 196.342 172.460 1.00 45.25  ? 119 ILE B CG2 1 
ATOM   4714  C  CD1 . ILE B 1 119 ? 163.719 198.340 170.184 1.00 45.25  ? 119 ILE B CD1 1 
ATOM   4715  N  N   . TYR B 1 120 ? 159.801 195.210 172.705 1.00 49.86  ? 120 TYR B N   1 
ATOM   4716  C  CA  . TYR B 1 120 ? 159.243 194.730 173.965 1.00 49.86  ? 120 TYR B CA  1 
ATOM   4717  C  C   . TYR B 1 120 ? 158.472 193.428 173.785 1.00 49.86  ? 120 TYR B C   1 
ATOM   4718  O  O   . TYR B 1 120 ? 158.627 192.496 174.580 1.00 49.86  ? 120 TYR B O   1 
ATOM   4719  C  CB  . TYR B 1 120 ? 158.356 195.800 174.600 1.00 49.86  ? 120 TYR B CB  1 
ATOM   4720  C  CG  . TYR B 1 120 ? 159.133 196.953 175.188 1.00 49.86  ? 120 TYR B CG  1 
ATOM   4721  C  CD1 . TYR B 1 120 ? 160.509 196.892 175.311 1.00 49.86  ? 120 TYR B CD1 1 
ATOM   4722  C  CD2 . TYR B 1 120 ? 158.489 198.084 175.655 1.00 49.86  ? 120 TYR B CD2 1 
ATOM   4723  C  CE1 . TYR B 1 120 ? 161.225 197.934 175.854 1.00 49.86  ? 120 TYR B CE1 1 
ATOM   4724  C  CE2 . TYR B 1 120 ? 159.201 199.131 176.206 1.00 49.86  ? 120 TYR B CE2 1 
ATOM   4725  C  CZ  . TYR B 1 120 ? 160.569 199.048 176.301 1.00 49.86  ? 120 TYR B CZ  1 
ATOM   4726  O  OH  . TYR B 1 120 ? 161.289 200.082 176.845 1.00 49.86  ? 120 TYR B OH  1 
ATOM   4727  N  N   . HIS B 1 121 ? 157.637 193.344 172.751 1.00 53.21  ? 121 HIS B N   1 
ATOM   4728  C  CA  . HIS B 1 121 ? 156.824 192.154 172.520 1.00 53.21  ? 121 HIS B CA  1 
ATOM   4729  C  C   . HIS B 1 121 ? 157.530 191.133 171.636 1.00 53.21  ? 121 HIS B C   1 
ATOM   4730  O  O   . HIS B 1 121 ? 157.788 190.006 172.068 1.00 53.21  ? 121 HIS B O   1 
ATOM   4731  C  CB  . HIS B 1 121 ? 155.485 192.541 171.889 1.00 53.21  ? 121 HIS B CB  1 
ATOM   4732  C  CG  . HIS B 1 121 ? 154.578 193.302 172.803 1.00 53.21  ? 121 HIS B CG  1 
ATOM   4733  N  ND1 . HIS B 1 121 ? 153.414 193.897 172.366 1.00 53.21  ? 121 HIS B ND1 1 
ATOM   4734  C  CD2 . HIS B 1 121 ? 154.659 193.564 174.129 1.00 53.21  ? 121 HIS B CD2 1 
ATOM   4735  C  CE1 . HIS B 1 121 ? 152.818 194.493 173.383 1.00 53.21  ? 121 HIS B CE1 1 
ATOM   4736  N  NE2 . HIS B 1 121 ? 153.552 194.305 174.465 1.00 53.21  ? 121 HIS B NE2 1 
ATOM   4737  N  N   . GLY B 1 122 ? 157.843 191.507 170.400 1.00 43.64  ? 122 GLY B N   1 
ATOM   4738  C  CA  . GLY B 1 122 ? 158.395 190.595 169.419 1.00 43.64  ? 122 GLY B CA  1 
ATOM   4739  C  C   . GLY B 1 122 ? 157.513 190.388 168.210 1.00 43.64  ? 122 GLY B C   1 
ATOM   4740  O  O   . GLY B 1 122 ? 157.906 189.655 167.294 1.00 43.64  ? 122 GLY B O   1 
ATOM   4741  N  N   . THR B 1 123 ? 156.338 191.011 168.175 1.00 44.72  ? 123 THR B N   1 
ATOM   4742  C  CA  . THR B 1 123 ? 155.394 190.879 167.076 1.00 44.72  ? 123 THR B CA  1 
ATOM   4743  C  C   . THR B 1 123 ? 155.123 192.253 166.487 1.00 44.72  ? 123 THR B C   1 
ATOM   4744  O  O   . THR B 1 123 ? 154.549 193.117 167.158 1.00 44.72  ? 123 THR B O   1 
ATOM   4745  C  CB  . THR B 1 123 ? 154.080 190.261 167.548 1.00 44.72  ? 123 THR B CB  1 
ATOM   4746  O  OG1 . THR B 1 123 ? 153.437 191.161 168.456 1.00 44.72  ? 123 THR B OG1 1 
ATOM   4747  C  CG2 . THR B 1 123 ? 154.343 188.957 168.270 1.00 44.72  ? 123 THR B CG2 1 
ATOM   4748  N  N   . VAL B 1 124 ? 155.526 192.450 165.237 1.00 41.46  ? 124 VAL B N   1 
ATOM   4749  C  CA  . VAL B 1 124 ? 155.303 193.697 164.519 1.00 41.46  ? 124 VAL B CA  1 
ATOM   4750  C  C   . VAL B 1 124 ? 154.380 193.407 163.345 1.00 41.46  ? 124 VAL B C   1 
ATOM   4751  O  O   . VAL B 1 124 ? 154.379 192.295 162.805 1.00 41.46  ? 124 VAL B O   1 
ATOM   4752  C  CB  . VAL B 1 124 ? 156.632 194.328 164.050 1.00 41.46  ? 124 VAL B CB  1 
ATOM   4753  C  CG1 . VAL B 1 124 ? 157.314 193.448 163.024 1.00 41.46  ? 124 VAL B CG1 1 
ATOM   4754  C  CG2 . VAL B 1 124 ? 156.411 195.729 163.507 1.00 41.46  ? 124 VAL B CG2 1 
ATOM   4755  N  N   . LYS B 1 125 ? 153.576 194.398 162.968 1.00 42.07  ? 125 LYS B N   1 
ATOM   4756  C  CA  . LYS B 1 125 ? 152.599 194.267 161.893 1.00 42.07  ? 125 LYS B CA  1 
ATOM   4757  C  C   . LYS B 1 125 ? 153.174 194.918 160.640 1.00 42.07  ? 125 LYS B C   1 
ATOM   4758  O  O   . LYS B 1 125 ? 153.039 196.129 160.445 1.00 42.07  ? 125 LYS B O   1 
ATOM   4759  C  CB  . LYS B 1 125 ? 151.276 194.914 162.292 1.00 42.07  ? 125 LYS B CB  1 
ATOM   4760  C  CG  . LYS B 1 125 ? 150.152 194.720 161.294 1.00 42.07  ? 125 LYS B CG  1 
ATOM   4761  C  CD  . LYS B 1 125 ? 149.684 193.277 161.279 1.00 42.07  ? 125 LYS B CD  1 
ATOM   4762  C  CE  . LYS B 1 125 ? 148.567 193.060 160.275 1.00 42.07  ? 125 LYS B CE  1 
ATOM   4763  N  NZ  . LYS B 1 125 ? 147.326 193.787 160.641 1.00 42.07  ? 125 LYS B NZ  1 
ATOM   4764  N  N   . LEU B 1 126 ? 153.816 194.115 159.796 1.00 39.34  ? 126 LEU B N   1 
ATOM   4765  C  CA  . LEU B 1 126 ? 154.481 194.615 158.601 1.00 39.34  ? 126 LEU B CA  1 
ATOM   4766  C  C   . LEU B 1 126 ? 153.456 194.943 157.524 1.00 39.34  ? 126 LEU B C   1 
ATOM   4767  O  O   . LEU B 1 126 ? 152.550 194.148 157.259 1.00 39.34  ? 126 LEU B O   1 
ATOM   4768  C  CB  . LEU B 1 126 ? 155.482 193.586 158.078 1.00 39.34  ? 126 LEU B CB  1 
ATOM   4769  C  CG  . LEU B 1 126 ? 156.699 193.327 158.961 1.00 39.34  ? 126 LEU B CG  1 
ATOM   4770  C  CD1 . LEU B 1 126 ? 157.482 192.154 158.433 1.00 39.34  ? 126 LEU B CD1 1 
ATOM   4771  C  CD2 . LEU B 1 126 ? 157.570 194.563 159.018 1.00 39.34  ? 126 LEU B CD2 1 
ATOM   4772  N  N   . ARG B 1 127 ? 153.602 196.111 156.906 1.00 46.72  ? 127 ARG B N   1 
ATOM   4773  C  CA  . ARG B 1 127 ? 152.729 196.546 155.826 1.00 46.72  ? 127 ARG B CA  1 
ATOM   4774  C  C   . ARG B 1 127 ? 153.559 197.123 154.691 1.00 46.72  ? 127 ARG B C   1 
ATOM   4775  O  O   . ARG B 1 127 ? 154.589 197.760 154.925 1.00 46.72  ? 127 ARG B O   1 
ATOM   4776  C  CB  . ARG B 1 127 ? 151.718 197.584 156.311 1.00 46.72  ? 127 ARG B CB  1 
ATOM   4777  C  CG  . ARG B 1 127 ? 150.663 197.025 157.240 1.00 46.72  ? 127 ARG B CG  1 
ATOM   4778  C  CD  . ARG B 1 127 ? 149.625 198.072 157.588 1.00 46.72  ? 127 ARG B CD  1 
ATOM   4779  N  NE  . ARG B 1 127 ? 150.169 199.123 158.441 1.00 46.72  ? 127 ARG B NE  1 
ATOM   4780  C  CZ  . ARG B 1 127 ? 150.321 200.386 158.061 1.00 46.72  ? 127 ARG B CZ  1 
ATOM   4781  N  NH1 . ARG B 1 127 ? 149.970 200.758 156.838 1.00 46.72  ? 127 ARG B NH1 1 
ATOM   4782  N  NH2 . ARG B 1 127 ? 150.821 201.278 158.903 1.00 46.72  ? 127 ARG B NH2 1 
ATOM   4783  N  N   . ALA B 1 128 ? 153.099 196.904 153.457 1.00 46.55  ? 128 ALA B N   1 
ATOM   4784  C  CA  . ALA B 1 128 ? 153.841 197.374 152.295 1.00 46.55  ? 128 ALA B CA  1 
ATOM   4785  C  C   . ALA B 1 128 ? 153.798 198.887 152.148 1.00 46.55  ? 128 ALA B C   1 
ATOM   4786  O  O   . ALA B 1 128 ? 154.614 199.445 151.409 1.00 46.55  ? 128 ALA B O   1 
ATOM   4787  C  CB  . ALA B 1 128 ? 153.306 196.716 151.024 1.00 46.55  ? 128 ALA B CB  1 
ATOM   4788  N  N   . GLU B 1 129 ? 152.868 199.563 152.825 1.00 53.75  ? 129 GLU B N   1 
ATOM   4789  C  CA  . GLU B 1 129 ? 152.818 201.020 152.751 1.00 53.75  ? 129 GLU B CA  1 
ATOM   4790  C  C   . GLU B 1 129 ? 154.040 201.647 153.409 1.00 53.75  ? 129 GLU B C   1 
ATOM   4791  O  O   . GLU B 1 129 ? 154.869 202.263 152.731 1.00 53.75  ? 129 GLU B O   1 
ATOM   4792  C  CB  . GLU B 1 129 ? 151.530 201.534 153.395 1.00 53.75  ? 129 GLU B CB  1 
ATOM   4793  C  CG  . GLU B 1 129 ? 150.261 201.178 152.628 1.00 53.75  ? 129 GLU B CG  1 
ATOM   4794  C  CD  . GLU B 1 129 ? 149.737 199.790 152.954 1.00 53.75  ? 129 GLU B CD  1 
ATOM   4795  O  OE1 . GLU B 1 129 ? 150.309 199.128 153.844 1.00 53.75  ? 129 GLU B OE1 1 
ATOM   4796  O  OE2 . GLU B 1 129 ? 148.754 199.357 152.315 1.00 53.75  ? 129 GLU B OE2 1 
ATOM   4797  N  N   . GLU B 1 130 ? 154.172 201.498 154.723 1.00 50.48  ? 130 GLU B N   1 
ATOM   4798  C  CA  . GLU B 1 130 ? 155.338 201.960 155.465 1.00 50.48  ? 130 GLU B CA  1 
ATOM   4799  C  C   . GLU B 1 130 ? 156.332 200.823 155.670 1.00 50.48  ? 130 GLU B C   1 
ATOM   4800  O  O   . GLU B 1 130 ? 156.410 200.211 156.736 1.00 50.48  ? 130 GLU B O   1 
ATOM   4801  C  CB  . GLU B 1 130 ? 154.921 202.599 156.791 1.00 50.48  ? 130 GLU B CB  1 
ATOM   4802  C  CG  . GLU B 1 130 ? 154.085 201.723 157.715 1.00 50.48  ? 130 GLU B CG  1 
ATOM   4803  C  CD  . GLU B 1 130 ? 153.672 202.443 158.983 1.00 50.48  ? 130 GLU B CD  1 
ATOM   4804  O  OE1 . GLU B 1 130 ? 154.011 203.636 159.129 1.00 50.48  ? 130 GLU B OE1 1 
ATOM   4805  O  OE2 . GLU B 1 130 ? 153.009 201.815 159.834 1.00 50.48  ? 130 GLU B OE2 1 
ATOM   4806  N  N   . LEU B 1 131 ? 157.107 200.523 154.633 1.00 42.92  ? 131 LEU B N   1 
ATOM   4807  C  CA  . LEU B 1 131 ? 158.050 199.416 154.693 1.00 42.92  ? 131 LEU B CA  1 
ATOM   4808  C  C   . LEU B 1 131 ? 159.496 199.869 154.599 1.00 42.92  ? 131 LEU B C   1 
ATOM   4809  O  O   . LEU B 1 131 ? 160.257 199.694 155.557 1.00 42.92  ? 131 LEU B O   1 
ATOM   4810  C  CB  . LEU B 1 131 ? 157.765 198.420 153.575 1.00 42.92  ? 131 LEU B CB  1 
ATOM   4811  C  CG  . LEU B 1 131 ? 158.738 197.254 153.512 1.00 42.92  ? 131 LEU B CG  1 
ATOM   4812  C  CD1 . LEU B 1 131 ? 158.675 196.439 154.782 1.00 42.92  ? 131 LEU B CD1 1 
ATOM   4813  C  CD2 . LEU B 1 131 ? 158.391 196.421 152.315 1.00 42.92  ? 131 LEU B CD2 1 
ATOM   4814  N  N   . GLN B 1 132 ? 159.884 200.435 153.453 1.00 44.89  ? 132 GLN B N   1 
ATOM   4815  C  CA  . GLN B 1 132 ? 161.266 200.854 153.255 1.00 44.89  ? 132 GLN B CA  1 
ATOM   4816  C  C   . GLN B 1 132 ? 161.765 201.669 154.435 1.00 44.89  ? 132 GLN B C   1 
ATOM   4817  O  O   . GLN B 1 132 ? 162.855 201.405 154.957 1.00 44.89  ? 132 GLN B O   1 
ATOM   4818  C  CB  . GLN B 1 132 ? 161.393 201.651 151.959 1.00 44.89  ? 132 GLN B CB  1 
ATOM   4819  C  CG  . GLN B 1 132 ? 161.135 200.830 150.709 1.00 44.89  ? 132 GLN B CG  1 
ATOM   4820  C  CD  . GLN B 1 132 ? 161.282 201.639 149.440 1.00 44.89  ? 132 GLN B CD  1 
ATOM   4821  O  OE1 . GLN B 1 132 ? 161.532 202.844 149.483 1.00 44.89  ? 132 GLN B OE1 1 
ATOM   4822  N  NE2 . GLN B 1 132 ? 161.123 200.981 148.298 1.00 44.89  ? 132 GLN B NE2 1 
ATOM   4823  N  N   . GLU B 1 133 ? 160.959 202.631 154.894 1.00 48.22  ? 133 GLU B N   1 
ATOM   4824  C  CA  . GLU B 1 133 ? 161.320 203.415 156.070 1.00 48.22  ? 133 GLU B CA  1 
ATOM   4825  C  C   . GLU B 1 133 ? 161.744 202.517 157.222 1.00 48.22  ? 133 GLU B C   1 
ATOM   4826  O  O   . GLU B 1 133 ? 162.891 202.597 157.682 1.00 48.22  ? 133 GLU B O   1 
ATOM   4827  C  CB  . GLU B 1 133 ? 160.154 204.309 156.484 1.00 48.22  ? 133 GLU B CB  1 
ATOM   4828  C  CG  . GLU B 1 133 ? 160.472 205.233 157.645 1.00 48.22  ? 133 GLU B CG  1 
ATOM   4829  C  CD  . GLU B 1 133 ? 159.332 206.178 157.970 1.00 48.22  ? 133 GLU B CD  1 
ATOM   4830  O  OE1 . GLU B 1 133 ? 158.282 206.097 157.299 1.00 48.22  ? 133 GLU B OE1 1 
ATOM   4831  O  OE2 . GLU B 1 133 ? 159.486 207.003 158.895 1.00 48.22  ? 133 GLU B OE2 1 
ATOM   4832  N  N   . ILE B 1 134 ? 160.848 201.632 157.676 1.00 42.96  ? 134 ILE B N   1 
ATOM   4833  C  CA  . ILE B 1 134 ? 161.218 200.662 158.705 1.00 42.96  ? 134 ILE B CA  1 
ATOM   4834  C  C   . ILE B 1 134 ? 162.544 200.011 158.358 1.00 42.96  ? 134 ILE B C   1 
ATOM   4835  O  O   . ILE B 1 134 ? 163.497 200.056 159.147 1.00 42.96  ? 134 ILE B O   1 
ATOM   4836  C  CB  . ILE B 1 134 ? 160.113 199.607 158.890 1.00 42.96  ? 134 ILE B CB  1 
ATOM   4837  C  CG1 . ILE B 1 134 ? 158.852 200.233 159.476 1.00 42.96  ? 134 ILE B CG1 1 
ATOM   4838  C  CG2 . ILE B 1 134 ? 160.597 198.488 159.783 1.00 42.96  ? 134 ILE B CG2 1 
ATOM   4839  C  CD1 . ILE B 1 134 ? 157.680 199.285 159.508 1.00 42.96  ? 134 ILE B CD1 1 
ATOM   4840  N  N   . TYR B 1 135 ? 162.634 199.436 157.154 1.00 44.29  ? 135 TYR B N   1 
ATOM   4841  C  CA  . TYR B 1 135 ? 163.891 198.885 156.656 1.00 44.29  ? 135 TYR B CA  1 
ATOM   4842  C  C   . TYR B 1 135 ? 165.057 199.794 157.010 1.00 44.29  ? 135 TYR B C   1 
ATOM   4843  O  O   . TYR B 1 135 ? 165.900 199.446 157.846 1.00 44.29  ? 135 TYR B O   1 
ATOM   4844  C  CB  . TYR B 1 135 ? 163.792 198.693 155.143 1.00 44.29  ? 135 TYR B CB  1 
ATOM   4845  C  CG  . TYR B 1 135 ? 164.993 198.059 154.489 1.00 44.29  ? 135 TYR B CG  1 
ATOM   4846  C  CD1 . TYR B 1 135 ? 165.183 196.690 154.522 1.00 44.29  ? 135 TYR B CD1 1 
ATOM   4847  C  CD2 . TYR B 1 135 ? 165.934 198.829 153.830 1.00 44.29  ? 135 TYR B CD2 1 
ATOM   4848  C  CE1 . TYR B 1 135 ? 166.278 196.107 153.915 1.00 44.29  ? 135 TYR B CE1 1 
ATOM   4849  C  CE2 . TYR B 1 135 ? 167.034 198.254 153.228 1.00 44.29  ? 135 TYR B CE2 1 
ATOM   4850  C  CZ  . TYR B 1 135 ? 167.198 196.895 153.271 1.00 44.29  ? 135 TYR B CZ  1 
ATOM   4851  O  OH  . TYR B 1 135 ? 168.291 196.319 152.672 1.00 44.29  ? 135 TYR B OH  1 
ATOM   4852  N  N   . GLU B 1 136 ? 165.069 201.001 156.439 1.00 45.28  ? 136 GLU B N   1 
ATOM   4853  C  CA  . GLU B 1 136 ? 166.148 201.943 156.705 1.00 45.28  ? 136 GLU B CA  1 
ATOM   4854  C  C   . GLU B 1 136 ? 166.359 202.112 158.200 1.00 45.28  ? 136 GLU B C   1 
ATOM   4855  O  O   . GLU B 1 136 ? 167.466 201.898 158.711 1.00 45.28  ? 136 GLU B O   1 
ATOM   4856  C  CB  . GLU B 1 136 ? 165.832 203.284 156.048 1.00 45.28  ? 136 GLU B CB  1 
ATOM   4857  C  CG  . GLU B 1 136 ? 165.759 203.225 154.535 1.00 45.28  ? 136 GLU B CG  1 
ATOM   4858  C  CD  . GLU B 1 136 ? 165.387 204.556 153.920 1.00 45.28  ? 136 GLU B CD  1 
ATOM   4859  O  OE1 . GLU B 1 136 ? 165.075 205.495 154.681 1.00 45.28  ? 136 GLU B OE1 1 
ATOM   4860  O  OE2 . GLU B 1 136 ? 165.402 204.665 152.677 1.00 45.28  ? 136 GLU B OE2 1 
ATOM   4861  N  N   . VAL B 1 137 ? 165.286 202.430 158.928 1.00 43.61  ? 137 VAL B N   1 
ATOM   4862  C  CA  . VAL B 1 137 ? 165.412 202.699 160.354 1.00 43.61  ? 137 VAL B CA  1 
ATOM   4863  C  C   . VAL B 1 137 ? 165.971 201.483 161.073 1.00 43.61  ? 137 VAL B C   1 
ATOM   4864  O  O   . VAL B 1 137 ? 166.850 201.606 161.935 1.00 43.61  ? 137 VAL B O   1 
ATOM   4865  C  CB  . VAL B 1 137 ? 164.059 203.139 160.938 1.00 43.61  ? 137 VAL B CB  1 
ATOM   4866  C  CG1 . VAL B 1 137 ? 164.167 203.308 162.426 1.00 43.61  ? 137 VAL B CG1 1 
ATOM   4867  C  CG2 . VAL B 1 137 ? 163.611 204.438 160.300 1.00 43.61  ? 137 VAL B CG2 1 
ATOM   4868  N  N   . SER B 1 138 ? 165.510 200.287 160.697 1.00 41.28  ? 138 SER B N   1 
ATOM   4869  C  CA  . SER B 1 138 ? 166.035 199.081 161.325 1.00 41.28  ? 138 SER B CA  1 
ATOM   4870  C  C   . SER B 1 138 ? 167.543 199.002 161.158 1.00 41.28  ? 138 SER B C   1 
ATOM   4871  O  O   . SER B 1 138 ? 168.274 198.776 162.130 1.00 41.28  ? 138 SER B O   1 
ATOM   4872  C  CB  . SER B 1 138 ? 165.362 197.849 160.732 1.00 41.28  ? 138 SER B CB  1 
ATOM   4873  O  OG  . SER B 1 138 ? 165.891 196.665 161.292 1.00 41.28  ? 138 SER B OG  1 
ATOM   4874  N  N   . ASP B 1 139 ? 168.031 199.253 159.941 1.00 49.93  ? 139 ASP B N   1 
ATOM   4875  C  CA  . ASP B 1 139 ? 169.460 199.146 159.678 1.00 49.93  ? 139 ASP B CA  1 
ATOM   4876  C  C   . ASP B 1 139 ? 170.237 200.185 160.475 1.00 49.93  ? 139 ASP B C   1 
ATOM   4877  O  O   . ASP B 1 139 ? 171.426 200.002 160.757 1.00 49.93  ? 139 ASP B O   1 
ATOM   4878  C  CB  . ASP B 1 139 ? 169.720 199.303 158.181 1.00 49.93  ? 139 ASP B CB  1 
ATOM   4879  C  CG  . ASP B 1 139 ? 171.112 198.866 157.775 1.00 49.93  ? 139 ASP B CG  1 
ATOM   4880  O  OD1 . ASP B 1 139 ? 171.885 198.416 158.644 1.00 49.93  ? 139 ASP B OD1 1 
ATOM   4881  O  OD2 . ASP B 1 139 ? 171.438 198.975 156.575 1.00 49.93  ? 139 ASP B OD2 1 
ATOM   4882  N  N   . MET B 1 140 ? 169.577 201.278 160.863 1.00 48.72  ? 140 MET B N   1 
ATOM   4883  C  CA  . MET B 1 140 ? 170.269 202.293 161.647 1.00 48.72  ? 140 MET B CA  1 
ATOM   4884  C  C   . MET B 1 140 ? 170.303 201.922 163.122 1.00 48.72  ? 140 MET B C   1 
ATOM   4885  O  O   . MET B 1 140 ? 171.204 202.357 163.848 1.00 48.72  ? 140 MET B O   1 
ATOM   4886  C  CB  . MET B 1 140 ? 169.608 203.656 161.442 1.00 48.72  ? 140 MET B CB  1 
ATOM   4887  C  CG  . MET B 1 140 ? 170.322 204.805 162.127 1.00 48.72  ? 140 MET B CG  1 
ATOM   4888  S  SD  . MET B 1 140 ? 169.586 206.409 161.759 1.00 48.72  ? 140 MET B SD  1 
ATOM   4889  C  CE  . MET B 1 140 ? 168.066 206.325 162.700 1.00 48.72  ? 140 MET B CE  1 
ATOM   4890  N  N   . TYR B 1 141 ? 169.353 201.108 163.577 1.00 46.66  ? 141 TYR B N   1 
ATOM   4891  C  CA  . TYR B 1 141 ? 169.305 200.683 164.969 1.00 46.66  ? 141 TYR B CA  1 
ATOM   4892  C  C   . TYR B 1 141 ? 169.905 199.303 165.179 1.00 46.66  ? 141 TYR B C   1 
ATOM   4893  O  O   . TYR B 1 141 ? 169.909 198.813 166.311 1.00 46.66  ? 141 TYR B O   1 
ATOM   4894  C  CB  . TYR B 1 141 ? 167.864 200.698 165.479 1.00 46.66  ? 141 TYR B CB  1 
ATOM   4895  C  CG  . TYR B 1 141 ? 167.275 202.081 165.584 1.00 46.66  ? 141 TYR B CG  1 
ATOM   4896  C  CD1 . TYR B 1 141 ? 168.083 203.203 165.546 1.00 46.66  ? 141 TYR B CD1 1 
ATOM   4897  C  CD2 . TYR B 1 141 ? 165.913 202.266 165.716 1.00 46.66  ? 141 TYR B CD2 1 
ATOM   4898  C  CE1 . TYR B 1 141 ? 167.549 204.468 165.638 1.00 46.66  ? 141 TYR B CE1 1 
ATOM   4899  C  CE2 . TYR B 1 141 ? 165.372 203.528 165.809 1.00 46.66  ? 141 TYR B CE2 1 
ATOM   4900  C  CZ  . TYR B 1 141 ? 166.195 204.626 165.768 1.00 46.66  ? 141 TYR B CZ  1 
ATOM   4901  O  OH  . TYR B 1 141 ? 165.656 205.887 165.860 1.00 46.66  ? 141 TYR B OH  1 
ATOM   4902  N  N   . GLN B 1 142 ? 170.397 198.671 164.115 1.00 47.96  ? 142 GLN B N   1 
ATOM   4903  C  CA  . GLN B 1 142 ? 171.074 197.378 164.190 1.00 47.96  ? 142 GLN B CA  1 
ATOM   4904  C  C   . GLN B 1 142 ? 170.161 196.295 164.763 1.00 47.96  ? 142 GLN B C   1 
ATOM   4905  O  O   . GLN B 1 142 ? 170.610 195.379 165.452 1.00 47.96  ? 142 GLN B O   1 
ATOM   4906  C  CB  . GLN B 1 142 ? 172.374 197.483 164.987 1.00 47.96  ? 142 GLN B CB  1 
ATOM   4907  C  CG  . GLN B 1 142 ? 173.413 198.364 164.316 1.00 47.96  ? 142 GLN B CG  1 
ATOM   4908  C  CD  . GLN B 1 142 ? 174.698 198.463 165.109 1.00 47.96  ? 142 GLN B CD  1 
ATOM   4909  O  OE1 . GLN B 1 142 ? 174.813 197.902 166.195 1.00 47.96  ? 142 GLN B OE1 1 
ATOM   4910  N  NE2 . GLN B 1 142 ? 175.671 199.186 164.570 1.00 47.96  ? 142 GLN B NE2 1 
ATOM   4911  N  N   . LEU B 1 143 ? 168.866 196.401 164.475 1.00 42.85  ? 143 LEU B N   1 
ATOM   4912  C  CA  . LEU B 1 143 ? 167.915 195.320 164.727 1.00 42.85  ? 143 LEU B CA  1 
ATOM   4913  C  C   . LEU B 1 143 ? 168.032 194.348 163.560 1.00 42.85  ? 143 LEU B C   1 
ATOM   4914  O  O   . LEU B 1 143 ? 167.500 194.595 162.477 1.00 42.85  ? 143 LEU B O   1 
ATOM   4915  C  CB  . LEU B 1 143 ? 166.496 195.861 164.873 1.00 42.85  ? 143 LEU B CB  1 
ATOM   4916  C  CG  . LEU B 1 143 ? 166.198 196.729 166.097 1.00 42.85  ? 143 LEU B CG  1 
ATOM   4917  C  CD1 . LEU B 1 143 ? 164.815 197.340 166.007 1.00 42.85  ? 143 LEU B CD1 1 
ATOM   4918  C  CD2 . LEU B 1 143 ? 166.327 195.909 167.362 1.00 42.85  ? 143 LEU B CD2 1 
ATOM   4919  N  N   . THR B 1 144 ? 168.732 193.236 163.780 1.00 47.82  ? 144 THR B N   1 
ATOM   4920  C  CA  . THR B 1 144 ? 169.119 192.375 162.667 1.00 47.82  ? 144 THR B CA  1 
ATOM   4921  C  C   . THR B 1 144 ? 167.929 191.603 162.109 1.00 47.82  ? 144 THR B C   1 
ATOM   4922  O  O   . THR B 1 144 ? 167.745 191.525 160.889 1.00 47.82  ? 144 THR B O   1 
ATOM   4923  C  CB  . THR B 1 144 ? 170.224 191.415 163.107 1.00 47.82  ? 144 THR B CB  1 
ATOM   4924  O  OG1 . THR B 1 144 ? 171.365 192.167 163.537 1.00 47.82  ? 144 THR B OG1 1 
ATOM   4925  C  CG2 . THR B 1 144 ? 170.629 190.508 161.960 1.00 47.82  ? 144 THR B CG2 1 
ATOM   4926  N  N   . SER B 1 145 ? 167.107 191.023 162.985 1.00 44.46  ? 145 SER B N   1 
ATOM   4927  C  CA  . SER B 1 145 ? 166.017 190.171 162.518 1.00 44.46  ? 145 SER B CA  1 
ATOM   4928  C  C   . SER B 1 145 ? 164.980 190.970 161.736 1.00 44.46  ? 145 SER B C   1 
ATOM   4929  O  O   . SER B 1 145 ? 164.527 190.542 160.666 1.00 44.46  ? 145 SER B O   1 
ATOM   4930  C  CB  . SER B 1 145 ? 165.373 189.459 163.704 1.00 44.46  ? 145 SER B CB  1 
ATOM   4931  O  OG  . SER B 1 145 ? 166.295 188.581 164.326 1.00 44.46  ? 145 SER B OG  1 
ATOM   4932  N  N   . LEU B 1 146 ? 164.597 192.139 162.249 1.00 40.08  ? 146 LEU B N   1 
ATOM   4933  C  CA  . LEU B 1 146 ? 163.615 192.958 161.547 1.00 40.08  ? 146 LEU B CA  1 
ATOM   4934  C  C   . LEU B 1 146 ? 164.181 193.496 160.239 1.00 40.08  ? 146 LEU B C   1 
ATOM   4935  O  O   . LEU B 1 146 ? 163.447 193.654 159.257 1.00 40.08  ? 146 LEU B O   1 
ATOM   4936  C  CB  . LEU B 1 146 ? 163.148 194.097 162.448 1.00 40.08  ? 146 LEU B CB  1 
ATOM   4937  C  CG  . LEU B 1 146 ? 162.041 194.987 161.892 1.00 40.08  ? 146 LEU B CG  1 
ATOM   4938  C  CD1 . LEU B 1 146 ? 160.796 194.166 161.622 1.00 40.08  ? 146 LEU B CD1 1 
ATOM   4939  C  CD2 . LEU B 1 146 ? 161.737 196.113 162.856 1.00 40.08  ? 146 LEU B CD2 1 
ATOM   4940  N  N   . PHE B 1 147 ? 165.484 193.780 160.203 1.00 44.29  ? 147 PHE B N   1 
ATOM   4941  C  CA  . PHE B 1 147 ? 166.116 194.193 158.955 1.00 44.29  ? 147 PHE B CA  1 
ATOM   4942  C  C   . PHE B 1 147 ? 166.096 193.071 157.927 1.00 44.29  ? 147 PHE B C   1 
ATOM   4943  O  O   . PHE B 1 147 ? 165.864 193.313 156.737 1.00 44.29  ? 147 PHE B O   1 
ATOM   4944  C  CB  . PHE B 1 147 ? 167.548 194.645 159.220 1.00 44.29  ? 147 PHE B CB  1 
ATOM   4945  C  CG  . PHE B 1 147 ? 168.299 195.023 157.983 1.00 44.29  ? 147 PHE B CG  1 
ATOM   4946  C  CD1 . PHE B 1 147 ? 168.055 196.224 157.350 1.00 44.29  ? 147 PHE B CD1 1 
ATOM   4947  C  CD2 . PHE B 1 147 ? 169.250 194.173 157.451 1.00 44.29  ? 147 PHE B CD2 1 
ATOM   4948  C  CE1 . PHE B 1 147 ? 168.745 196.572 156.213 1.00 44.29  ? 147 PHE B CE1 1 
ATOM   4949  C  CE2 . PHE B 1 147 ? 169.942 194.517 156.312 1.00 44.29  ? 147 PHE B CE2 1 
ATOM   4950  C  CZ  . PHE B 1 147 ? 169.689 195.718 155.693 1.00 44.29  ? 147 PHE B CZ  1 
ATOM   4951  N  N   . GLU B 1 148 ? 166.340 191.834 158.363 1.00 47.32  ? 148 GLU B N   1 
ATOM   4952  C  CA  . GLU B 1 148 ? 166.342 190.720 157.422 1.00 47.32  ? 148 GLU B CA  1 
ATOM   4953  C  C   . GLU B 1 148 ? 164.935 190.412 156.930 1.00 47.32  ? 148 GLU B C   1 
ATOM   4954  O  O   . GLU B 1 148 ? 164.749 190.015 155.773 1.00 47.32  ? 148 GLU B O   1 
ATOM   4955  C  CB  . GLU B 1 148 ? 166.975 189.488 158.064 1.00 47.32  ? 148 GLU B CB  1 
ATOM   4956  C  CG  . GLU B 1 148 ? 168.465 189.635 158.324 1.00 47.32  ? 148 GLU B CG  1 
ATOM   4957  C  CD  . GLU B 1 148 ? 169.076 188.399 158.950 1.00 47.32  ? 148 GLU B CD  1 
ATOM   4958  O  OE1 . GLU B 1 148 ? 168.317 187.473 159.305 1.00 47.32  ? 148 GLU B OE1 1 
ATOM   4959  O  OE2 . GLU B 1 148 ? 170.316 188.350 159.084 1.00 47.32  ? 148 GLU B OE2 1 
ATOM   4960  N  N   . GLU B 1 149 ? 163.925 190.604 157.782 1.00 44.78  ? 149 GLU B N   1 
ATOM   4961  C  CA  . GLU B 1 149 ? 162.563 190.327 157.339 1.00 44.78  ? 149 GLU B CA  1 
ATOM   4962  C  C   . GLU B 1 149 ? 162.018 191.446 156.459 1.00 44.78  ? 149 GLU B C   1 
ATOM   4963  O  O   . GLU B 1 149 ? 161.228 191.189 155.543 1.00 44.78  ? 149 GLU B O   1 
ATOM   4964  C  CB  . GLU B 1 149 ? 161.645 190.092 158.532 1.00 44.78  ? 149 GLU B CB  1 
ATOM   4965  C  CG  . GLU B 1 149 ? 160.219 189.785 158.117 1.00 44.78  ? 149 GLU B CG  1 
ATOM   4966  C  CD  . GLU B 1 149 ? 160.103 188.505 157.308 1.00 44.78  ? 149 GLU B CD  1 
ATOM   4967  O  OE1 . GLU B 1 149 ? 160.950 187.605 157.483 1.00 44.78  ? 149 GLU B OE1 1 
ATOM   4968  O  OE2 . GLU B 1 149 ? 159.163 188.401 156.492 1.00 44.78  ? 149 GLU B OE2 1 
ATOM   4969  N  N   . CYS B 1 150 ? 162.413 192.692 156.718 1.00 40.70  ? 150 CYS B N   1 
ATOM   4970  C  CA  . CYS B 1 150 ? 162.050 193.764 155.798 1.00 40.70  ? 150 CYS B CA  1 
ATOM   4971  C  C   . CYS B 1 150 ? 162.814 193.635 154.487 1.00 40.70  ? 150 CYS B C   1 
ATOM   4972  O  O   . CYS B 1 150 ? 162.345 194.094 153.440 1.00 40.70  ? 150 CYS B O   1 
ATOM   4973  C  CB  . CYS B 1 150 ? 162.302 195.124 156.442 1.00 40.70  ? 150 CYS B CB  1 
ATOM   4974  S  SG  . CYS B 1 150 ? 161.231 195.491 157.840 1.00 40.70  ? 150 CYS B SG  1 
ATOM   4975  N  N   . SER B 1 151 ? 163.986 193.000 154.522 1.00 42.30  ? 151 SER B N   1 
ATOM   4976  C  CA  . SER B 1 151 ? 164.729 192.762 153.289 1.00 42.30  ? 151 SER B CA  1 
ATOM   4977  C  C   . SER B 1 151 ? 164.086 191.655 152.462 1.00 42.30  ? 151 SER B C   1 
ATOM   4978  O  O   . SER B 1 151 ? 163.994 191.762 151.232 1.00 42.30  ? 151 SER B O   1 
ATOM   4979  C  CB  . SER B 1 151 ? 166.180 192.420 153.612 1.00 42.30  ? 151 SER B CB  1 
ATOM   4980  O  OG  . SER B 1 151 ? 166.901 192.139 152.429 1.00 42.30  ? 151 SER B OG  1 
ATOM   4981  N  N   . ARG B 1 152 ? 163.631 190.583 153.115 1.00 41.22  ? 152 ARG B N   1 
ATOM   4982  C  CA  . ARG B 1 152 ? 162.918 189.537 152.388 1.00 41.22  ? 152 ARG B CA  1 
ATOM   4983  C  C   . ARG B 1 152 ? 161.569 190.037 151.886 1.00 41.22  ? 152 ARG B C   1 
ATOM   4984  O  O   . ARG B 1 152 ? 161.141 189.695 150.777 1.00 41.22  ? 152 ARG B O   1 
ATOM   4985  C  CB  . ARG B 1 152 ? 162.734 188.305 153.272 1.00 41.22  ? 152 ARG B CB  1 
ATOM   4986  C  CG  . ARG B 1 152 ? 164.020 187.567 153.579 1.00 41.22  ? 152 ARG B CG  1 
ATOM   4987  C  CD  . ARG B 1 152 ? 163.747 186.200 154.183 1.00 41.22  ? 152 ARG B CD  1 
ATOM   4988  N  NE  . ARG B 1 152 ? 163.104 186.278 155.490 1.00 41.22  ? 152 ARG B NE  1 
ATOM   4989  C  CZ  . ARG B 1 152 ? 163.762 186.329 156.643 1.00 41.22  ? 152 ARG B CZ  1 
ATOM   4990  N  NH1 . ARG B 1 152 ? 165.088 186.311 156.654 1.00 41.22  ? 152 ARG B NH1 1 
ATOM   4991  N  NH2 . ARG B 1 152 ? 163.094 186.395 157.785 1.00 41.22  ? 152 ARG B NH2 1 
ATOM   4992  N  N   . PHE B 1 153 ? 160.892 190.863 152.685 1.00 39.42  ? 153 PHE B N   1 
ATOM   4993  C  CA  . PHE B 1 153 ? 159.577 191.355 152.294 1.00 39.42  ? 153 PHE B CA  1 
ATOM   4994  C  C   . PHE B 1 153 ? 159.687 192.463 151.255 1.00 39.42  ? 153 PHE B C   1 
ATOM   4995  O  O   . PHE B 1 153 ? 158.716 192.763 150.554 1.00 39.42  ? 153 PHE B O   1 
ATOM   4996  C  CB  . PHE B 1 153 ? 158.812 191.810 153.537 1.00 39.42  ? 153 PHE B CB  1 
ATOM   4997  C  CG  . PHE B 1 153 ? 157.438 192.338 153.253 1.00 39.42  ? 153 PHE B CG  1 
ATOM   4998  C  CD1 . PHE B 1 153 ? 156.471 191.529 152.693 1.00 39.42  ? 153 PHE B CD1 1 
ATOM   4999  C  CD2 . PHE B 1 153 ? 157.087 193.615 153.621 1.00 39.42  ? 153 PHE B CD2 1 
ATOM   5000  C  CE1 . PHE B 1 153 ? 155.198 192.010 152.449 1.00 39.42  ? 153 PHE B CE1 1 
ATOM   5001  C  CE2 . PHE B 1 153 ? 155.816 194.098 153.381 1.00 39.42  ? 153 PHE B CE2 1 
ATOM   5002  C  CZ  . PHE B 1 153 ? 154.871 193.292 152.798 1.00 39.42  ? 153 PHE B CZ  1 
ATOM   5003  N  N   . LEU B 1 154 ? 160.865 193.082 151.136 1.00 39.77  ? 154 LEU B N   1 
ATOM   5004  C  CA  . LEU B 1 154 ? 161.141 193.905 149.961 1.00 39.77  ? 154 LEU B CA  1 
ATOM   5005  C  C   . LEU B 1 154 ? 161.499 193.041 148.761 1.00 39.77  ? 154 LEU B C   1 
ATOM   5006  O  O   . LEU B 1 154 ? 161.275 193.439 147.613 1.00 39.77  ? 154 LEU B O   1 
ATOM   5007  C  CB  . LEU B 1 154 ? 162.263 194.902 150.251 1.00 39.77  ? 154 LEU B CB  1 
ATOM   5008  C  CG  . LEU B 1 154 ? 161.930 196.161 151.044 1.00 39.77  ? 154 LEU B CG  1 
ATOM   5009  C  CD1 . LEU B 1 154 ? 163.196 196.871 151.455 1.00 39.77  ? 154 LEU B CD1 1 
ATOM   5010  C  CD2 . LEU B 1 154 ? 161.101 197.076 150.177 1.00 39.77  ? 154 LEU B CD2 1 
ATOM   5011  N  N   . ALA B 1 155 ? 162.063 191.855 149.002 1.00 44.24  ? 155 ALA B N   1 
ATOM   5012  C  CA  . ALA B 1 155 ? 162.367 190.957 147.893 1.00 44.24  ? 155 ALA B CA  1 
ATOM   5013  C  C   . ALA B 1 155 ? 161.104 190.363 147.281 1.00 44.24  ? 155 ALA B C   1 
ATOM   5014  O  O   . ALA B 1 155 ? 161.081 190.074 146.080 1.00 44.24  ? 155 ALA B O   1 
ATOM   5015  C  CB  . ALA B 1 155 ? 163.309 189.847 148.352 1.00 44.24  ? 155 ALA B CB  1 
ATOM   5016  N  N   . ARG B 1 156 ? 160.051 190.165 148.079 1.00 45.28  ? 156 ARG B N   1 
ATOM   5017  C  CA  . ARG B 1 156 ? 158.782 189.707 147.515 1.00 45.28  ? 156 ARG B CA  1 
ATOM   5018  C  C   . ARG B 1 156 ? 158.202 190.745 146.563 1.00 45.28  ? 156 ARG B C   1 
ATOM   5019  O  O   . ARG B 1 156 ? 158.194 190.555 145.342 1.00 45.28  ? 156 ARG B O   1 
ATOM   5020  C  CB  . ARG B 1 156 ? 157.771 189.412 148.622 1.00 45.28  ? 156 ARG B CB  1 
ATOM   5021  C  CG  . ARG B 1 156 ? 158.090 188.244 149.523 1.00 45.28  ? 156 ARG B CG  1 
ATOM   5022  C  CD  . ARG B 1 156 ? 156.975 188.063 150.537 1.00 45.28  ? 156 ARG B CD  1 
ATOM   5023  N  NE  . ARG B 1 156 ? 157.254 186.989 151.481 1.00 45.28  ? 156 ARG B NE  1 
ATOM   5024  C  CZ  . ARG B 1 156 ? 157.812 187.171 152.673 1.00 45.28  ? 156 ARG B CZ  1 
ATOM   5025  N  NH1 . ARG B 1 156 ? 158.136 188.389 153.072 1.00 45.28  ? 156 ARG B NH1 1 
ATOM   5026  N  NH2 . ARG B 1 156 ? 158.033 186.138 153.473 1.00 45.28  ? 156 ARG B NH2 1 
ATOM   5027  N  N   . THR B 1 157 ? 157.711 191.851 147.113 1.00 52.52  ? 157 THR B N   1 
ATOM   5028  C  CA  . THR B 1 157 ? 156.994 192.880 146.369 1.00 52.52  ? 157 THR B CA  1 
ATOM   5029  C  C   . THR B 1 157 ? 157.933 193.799 145.589 1.00 52.52  ? 157 THR B C   1 
ATOM   5030  O  O   . THR B 1 157 ? 157.911 195.021 145.746 1.00 52.52  ? 157 THR B O   1 
ATOM   5031  C  CB  . THR B 1 157 ? 156.095 193.680 147.313 1.00 52.52  ? 157 THR B CB  1 
ATOM   5032  O  OG1 . THR B 1 157 ? 155.411 194.707 146.584 1.00 52.52  ? 157 THR B OG1 1 
ATOM   5033  C  CG2 . THR B 1 157 ? 156.885 194.280 148.473 1.00 52.52  ? 157 THR B CG2 1 
ATOM   5034  N  N   . VAL B 1 158 ? 158.756 193.223 144.719 1.00 59.58  ? 158 VAL B N   1 
ATOM   5035  C  CA  . VAL B 1 158 ? 159.598 194.019 143.833 1.00 59.58  ? 158 VAL B CA  1 
ATOM   5036  C  C   . VAL B 1 158 ? 158.929 194.120 142.466 1.00 59.58  ? 158 VAL B C   1 
ATOM   5037  O  O   . VAL B 1 158 ? 158.877 193.150 141.700 1.00 59.58  ? 158 VAL B O   1 
ATOM   5038  C  CB  . VAL B 1 158 ? 161.021 193.433 143.754 1.00 59.58  ? 158 VAL B CB  1 
ATOM   5039  C  CG1 . VAL B 1 158 ? 161.022 191.978 143.294 1.00 59.58  ? 158 VAL B CG1 1 
ATOM   5040  C  CG2 . VAL B 1 158 ? 161.889 194.279 142.848 1.00 59.58  ? 158 VAL B CG2 1 
ATOM   5041  N  N   . GLN B 1 159 ? 158.386 195.295 142.167 1.00 68.99  ? 159 GLN B N   1 
ATOM   5042  C  CA  . GLN B 1 159 ? 157.610 195.514 140.960 1.00 68.99  ? 159 GLN B CA  1 
ATOM   5043  C  C   . GLN B 1 159 ? 158.549 195.690 139.770 1.00 68.99  ? 159 GLN B C   1 
ATOM   5044  O  O   . GLN B 1 159 ? 159.724 195.316 139.811 1.00 68.99  ? 159 GLN B O   1 
ATOM   5045  C  CB  . GLN B 1 159 ? 156.701 196.733 141.134 1.00 68.99  ? 159 GLN B CB  1 
ATOM   5046  C  CG  . GLN B 1 159 ? 155.707 196.636 142.281 1.00 68.99  ? 159 GLN B CG  1 
ATOM   5047  C  CD  . GLN B 1 159 ? 154.664 195.564 142.067 1.00 68.99  ? 159 GLN B CD  1 
ATOM   5048  O  OE1 . GLN B 1 159 ? 154.201 195.346 140.948 1.00 68.99  ? 159 GLN B OE1 1 
ATOM   5049  N  NE2 . GLN B 1 159 ? 154.278 194.893 143.145 1.00 68.99  ? 159 GLN B NE2 1 
ATOM   5050  N  N   . VAL B 1 160 ? 158.025 196.266 138.692 1.00 70.65  ? 160 VAL B N   1 
ATOM   5051  C  CA  . VAL B 1 160 ? 158.871 196.665 137.575 1.00 70.65  ? 160 VAL B CA  1 
ATOM   5052  C  C   . VAL B 1 160 ? 159.138 198.168 137.608 1.00 70.65  ? 160 VAL B C   1 
ATOM   5053  O  O   . VAL B 1 160 ? 160.108 198.638 137.004 1.00 70.65  ? 160 VAL B O   1 
ATOM   5054  C  CB  . VAL B 1 160 ? 158.235 196.235 136.241 1.00 70.65  ? 160 VAL B CB  1 
ATOM   5055  C  CG1 . VAL B 1 160 ? 156.959 197.019 135.977 1.00 70.65  ? 160 VAL B CG1 1 
ATOM   5056  C  CG2 . VAL B 1 160 ? 159.222 196.388 135.091 1.00 70.65  ? 160 VAL B CG2 1 
ATOM   5057  N  N   . GLY B 1 161 ? 158.304 198.933 138.318 1.00 67.56  ? 161 GLY B N   1 
ATOM   5058  C  CA  . GLY B 1 161 ? 158.531 200.359 138.453 1.00 67.56  ? 161 GLY B CA  1 
ATOM   5059  C  C   . GLY B 1 161 ? 159.505 200.737 139.546 1.00 67.56  ? 161 GLY B C   1 
ATOM   5060  O  O   . GLY B 1 161 ? 160.373 201.586 139.318 1.00 67.56  ? 161 GLY B O   1 
ATOM   5061  N  N   . ASN B 1 162 ? 159.383 200.127 140.727 1.00 65.89  ? 162 ASN B N   1 
ATOM   5062  C  CA  . ASN B 1 162 ? 160.317 200.355 141.823 1.00 65.89  ? 162 ASN B CA  1 
ATOM   5063  C  C   . ASN B 1 162 ? 161.447 199.332 141.827 1.00 65.89  ? 162 ASN B C   1 
ATOM   5064  O  O   . ASN B 1 162 ? 161.883 198.898 142.896 1.00 65.89  ? 162 ASN B O   1 
ATOM   5065  C  CB  . ASN B 1 162 ? 159.584 200.352 143.168 1.00 65.89  ? 162 ASN B CB  1 
ATOM   5066  C  CG  . ASN B 1 162 ? 158.925 199.018 143.484 1.00 65.89  ? 162 ASN B CG  1 
ATOM   5067  O  OD1 . ASN B 1 162 ? 159.092 198.036 142.763 1.00 65.89  ? 162 ASN B OD1 1 
ATOM   5068  N  ND2 . ASN B 1 162 ? 158.173 198.980 144.576 1.00 65.89  ? 162 ASN B ND2 1 
ATOM   5069  N  N   . CYS B 1 163 ? 161.925 198.930 140.649 1.00 63.99  ? 163 CYS B N   1 
ATOM   5070  C  CA  . CYS B 1 163 ? 162.979 197.925 140.593 1.00 63.99  ? 163 CYS B CA  1 
ATOM   5071  C  C   . CYS B 1 163 ? 164.356 198.566 140.487 1.00 63.99  ? 163 CYS B C   1 
ATOM   5072  O  O   . CYS B 1 163 ? 165.363 197.922 140.794 1.00 63.99  ? 163 CYS B O   1 
ATOM   5073  C  CB  . CYS B 1 163 ? 162.734 196.978 139.422 1.00 63.99  ? 163 CYS B CB  1 
ATOM   5074  S  SG  . CYS B 1 163 ? 163.856 195.577 139.365 1.00 63.99  ? 163 CYS B SG  1 
ATOM   5075  N  N   . LEU B 1 164 ? 164.421 199.822 140.051 1.00 68.62  ? 164 LEU B N   1 
ATOM   5076  C  CA  . LEU B 1 164 ? 165.658 200.587 140.078 1.00 68.62  ? 164 LEU B CA  1 
ATOM   5077  C  C   . LEU B 1 164 ? 165.789 201.446 141.325 1.00 68.62  ? 164 LEU B C   1 
ATOM   5078  O  O   . LEU B 1 164 ? 166.846 202.049 141.536 1.00 68.62  ? 164 LEU B O   1 
ATOM   5079  C  CB  . LEU B 1 164 ? 165.766 201.477 138.837 1.00 68.62  ? 164 LEU B CB  1 
ATOM   5080  C  CG  . LEU B 1 164 ? 165.942 200.765 137.498 1.00 68.62  ? 164 LEU B CG  1 
ATOM   5081  C  CD1 . LEU B 1 164 ? 165.891 201.770 136.366 1.00 68.62  ? 164 LEU B CD1 1 
ATOM   5082  C  CD2 . LEU B 1 164 ? 167.249 199.993 137.469 1.00 68.62  ? 164 LEU B CD2 1 
ATOM   5083  N  N   . GLN B 1 165 ? 164.743 201.527 142.145 1.00 58.03  ? 165 GLN B N   1 
ATOM   5084  C  CA  . GLN B 1 165 ? 164.833 202.215 143.424 1.00 58.03  ? 165 GLN B CA  1 
ATOM   5085  C  C   . GLN B 1 165 ? 165.098 201.252 144.571 1.00 58.03  ? 165 GLN B C   1 
ATOM   5086  O  O   . GLN B 1 165 ? 165.776 201.620 145.535 1.00 58.03  ? 165 GLN B O   1 
ATOM   5087  C  CB  . GLN B 1 165 ? 163.551 203.010 143.686 1.00 58.03  ? 165 GLN B CB  1 
ATOM   5088  C  CG  . GLN B 1 165 ? 163.627 203.972 144.860 1.00 58.03  ? 165 GLN B CG  1 
ATOM   5089  C  CD  . GLN B 1 165 ? 163.246 203.326 146.175 1.00 58.03  ? 165 GLN B CD  1 
ATOM   5090  O  OE1 . GLN B 1 165 ? 162.458 202.382 146.209 1.00 58.03  ? 165 GLN B OE1 1 
ATOM   5091  N  NE2 . GLN B 1 165 ? 163.800 203.836 147.269 1.00 58.03  ? 165 GLN B NE2 1 
ATOM   5092  N  N   . VAL B 1 166 ? 164.582 200.023 144.488 1.00 54.58  ? 166 VAL B N   1 
ATOM   5093  C  CA  . VAL B 1 166 ? 164.959 199.002 145.458 1.00 54.58  ? 166 VAL B CA  1 
ATOM   5094  C  C   . VAL B 1 166 ? 166.380 198.523 145.195 1.00 54.58  ? 166 VAL B C   1 
ATOM   5095  O  O   . VAL B 1 166 ? 167.101 198.153 146.128 1.00 54.58  ? 166 VAL B O   1 
ATOM   5096  C  CB  . VAL B 1 166 ? 163.950 197.839 145.435 1.00 54.58  ? 166 VAL B CB  1 
ATOM   5097  C  CG1 . VAL B 1 166 ? 164.430 196.693 146.302 1.00 54.58  ? 166 VAL B CG1 1 
ATOM   5098  C  CG2 . VAL B 1 166 ? 162.602 198.316 145.924 1.00 54.58  ? 166 VAL B CG2 1 
ATOM   5099  N  N   . MET B 1 167 ? 166.810 198.522 143.934 1.00 61.95  ? 167 MET B N   1 
ATOM   5100  C  CA  . MET B 1 167 ? 168.208 198.245 143.625 1.00 61.95  ? 167 MET B CA  1 
ATOM   5101  C  C   . MET B 1 167 ? 169.114 199.311 144.223 1.00 61.95  ? 167 MET B C   1 
ATOM   5102  O  O   . MET B 1 167 ? 170.138 199.002 144.841 1.00 61.95  ? 167 MET B O   1 
ATOM   5103  C  CB  . MET B 1 167 ? 168.403 198.177 142.114 1.00 61.95  ? 167 MET B CB  1 
ATOM   5104  C  CG  . MET B 1 167 ? 169.795 197.788 141.683 1.00 61.95  ? 167 MET B CG  1 
ATOM   5105  S  SD  . MET B 1 167 ? 169.966 197.907 139.901 1.00 61.95  ? 167 MET B SD  1 
ATOM   5106  C  CE  . MET B 1 167 ? 168.863 196.599 139.412 1.00 61.95  ? 167 MET B CE  1 
ATOM   5107  N  N   . TRP B 1 168 ? 168.753 200.580 144.037 1.00 65.68  ? 168 TRP B N   1 
ATOM   5108  C  CA  . TRP B 1 168 ? 169.529 201.682 144.587 1.00 65.68  ? 168 TRP B CA  1 
ATOM   5109  C  C   . TRP B 1 168 ? 169.400 201.777 146.100 1.00 65.68  ? 168 TRP B C   1 
ATOM   5110  O  O   . TRP B 1 168 ? 170.211 202.452 146.741 1.00 65.68  ? 168 TRP B O   1 
ATOM   5111  C  CB  . TRP B 1 168 ? 169.083 202.993 143.945 1.00 65.68  ? 168 TRP B CB  1 
ATOM   5112  C  CG  . TRP B 1 168 ? 169.872 204.176 144.372 1.00 65.68  ? 168 TRP B CG  1 
ATOM   5113  C  CD1 . TRP B 1 168 ? 169.502 205.122 145.280 1.00 65.68  ? 168 TRP B CD1 1 
ATOM   5114  C  CD2 . TRP B 1 168 ? 171.170 204.551 143.905 1.00 65.68  ? 168 TRP B CD2 1 
ATOM   5115  N  NE1 . TRP B 1 168 ? 170.492 206.064 145.410 1.00 65.68  ? 168 TRP B NE1 1 
ATOM   5116  C  CE2 . TRP B 1 168 ? 171.528 205.736 144.576 1.00 65.68  ? 168 TRP B CE2 1 
ATOM   5117  C  CE3 . TRP B 1 168 ? 172.065 203.999 142.985 1.00 65.68  ? 168 TRP B CE3 1 
ATOM   5118  C  CZ2 . TRP B 1 168 ? 172.742 206.378 144.357 1.00 65.68  ? 168 TRP B CZ2 1 
ATOM   5119  C  CZ3 . TRP B 1 168 ? 173.269 204.637 142.769 1.00 65.68  ? 168 TRP B CZ3 1 
ATOM   5120  C  CH2 . TRP B 1 168 ? 173.597 205.814 143.451 1.00 65.68  ? 168 TRP B CH2 1 
ATOM   5121  N  N   . LEU B 1 169 ? 168.397 201.124 146.679 1.00 56.81  ? 169 LEU B N   1 
ATOM   5122  C  CA  . LEU B 1 169 ? 168.196 201.136 148.119 1.00 56.81  ? 169 LEU B CA  1 
ATOM   5123  C  C   . LEU B 1 169 ? 168.909 199.992 148.822 1.00 56.81  ? 169 LEU B C   1 
ATOM   5124  O  O   . LEU B 1 169 ? 169.411 200.184 149.933 1.00 56.81  ? 169 LEU B O   1 
ATOM   5125  C  CB  . LEU B 1 169 ? 166.696 201.100 148.426 1.00 56.81  ? 169 LEU B CB  1 
ATOM   5126  C  CG  . LEU B 1 169 ? 166.195 201.217 149.860 1.00 56.81  ? 169 LEU B CG  1 
ATOM   5127  C  CD1 . LEU B 1 169 ? 164.888 201.975 149.879 1.00 56.81  ? 169 LEU B CD1 1 
ATOM   5128  C  CD2 . LEU B 1 169 ? 165.971 199.839 150.412 1.00 56.81  ? 169 LEU B CD2 1 
ATOM   5129  N  N   . ALA B 1 170 ? 168.975 198.815 148.203 1.00 55.98  ? 170 ALA B N   1 
ATOM   5130  C  CA  . ALA B 1 170 ? 169.734 197.696 148.739 1.00 55.98  ? 170 ALA B CA  1 
ATOM   5131  C  C   . ALA B 1 170 ? 171.222 197.800 148.459 1.00 55.98  ? 170 ALA B C   1 
ATOM   5132  O  O   . ALA B 1 170 ? 171.936 196.799 148.578 1.00 55.98  ? 170 ALA B O   1 
ATOM   5133  C  CB  . ALA B 1 170 ? 169.213 196.378 148.165 1.00 55.98  ? 170 ALA B CB  1 
ATOM   5134  N  N   . ASP B 1 171 ? 171.702 198.984 148.077 1.00 63.04  ? 171 ASP B N   1 
ATOM   5135  C  CA  . ASP B 1 171 ? 173.116 199.146 147.764 1.00 63.04  ? 171 ASP B CA  1 
ATOM   5136  C  C   . ASP B 1 171 ? 173.801 200.040 148.788 1.00 63.04  ? 171 ASP B C   1 
ATOM   5137  O  O   . ASP B 1 171 ? 174.935 199.769 149.198 1.00 63.04  ? 171 ASP B O   1 
ATOM   5138  C  CB  . ASP B 1 171 ? 173.272 199.716 146.356 1.00 63.04  ? 171 ASP B CB  1 
ATOM   5139  C  CG  . ASP B 1 171 ? 174.691 199.626 145.840 1.00 63.04  ? 171 ASP B CG  1 
ATOM   5140  O  OD1 . ASP B 1 171 ? 175.571 199.129 146.572 1.00 63.04  ? 171 ASP B OD1 1 
ATOM   5141  O  OD2 . ASP B 1 171 ? 174.927 200.049 144.691 1.00 63.04  ? 171 ASP B OD2 1 
ATOM   5142  N  N   . ARG B 1 172 ? 173.129 201.107 149.217 1.00 61.20  ? 172 ARG B N   1 
ATOM   5143  C  CA  . ARG B 1 172 ? 173.671 201.967 150.258 1.00 61.20  ? 172 ARG B CA  1 
ATOM   5144  C  C   . ARG B 1 172 ? 173.544 201.357 151.647 1.00 61.20  ? 172 ARG B C   1 
ATOM   5145  O  O   . ARG B 1 172 ? 174.026 201.955 152.615 1.00 61.20  ? 172 ARG B O   1 
ATOM   5146  C  CB  . ARG B 1 172 ? 172.987 203.334 150.218 1.00 61.20  ? 172 ARG B CB  1 
ATOM   5147  C  CG  . ARG B 1 172 ? 171.505 203.304 150.529 1.00 61.20  ? 172 ARG B CG  1 
ATOM   5148  C  CD  . ARG B 1 172 ? 170.889 204.686 150.380 1.00 61.20  ? 172 ARG B CD  1 
ATOM   5149  N  NE  . ARG B 1 172 ? 171.399 205.633 151.367 1.00 61.20  ? 172 ARG B NE  1 
ATOM   5150  C  CZ  . ARG B 1 172 ? 170.902 205.780 152.590 1.00 61.20  ? 172 ARG B CZ  1 
ATOM   5151  N  NH1 . ARG B 1 172 ? 169.873 205.041 152.984 1.00 61.20  ? 172 ARG B NH1 1 
ATOM   5152  N  NH2 . ARG B 1 172 ? 171.432 206.668 153.420 1.00 61.20  ? 172 ARG B NH2 1 
ATOM   5153  N  N   . HIS B 1 173 ? 172.914 200.189 151.765 1.00 55.49  ? 173 HIS B N   1 
ATOM   5154  C  CA  . HIS B 1 173 ? 172.838 199.455 153.020 1.00 55.49  ? 173 HIS B CA  1 
ATOM   5155  C  C   . HIS B 1 173 ? 173.703 198.204 153.026 1.00 55.49  ? 173 HIS B C   1 
ATOM   5156  O  O   . HIS B 1 173 ? 173.687 197.465 154.016 1.00 55.49  ? 173 HIS B O   1 
ATOM   5157  C  CB  . HIS B 1 173 ? 171.386 199.075 153.329 1.00 55.49  ? 173 HIS B CB  1 
ATOM   5158  C  CG  . HIS B 1 173 ? 170.501 200.247 153.610 1.00 55.49  ? 173 HIS B CG  1 
ATOM   5159  N  ND1 . HIS B 1 173 ? 170.559 200.956 154.789 1.00 55.49  ? 173 HIS B ND1 1 
ATOM   5160  C  CD2 . HIS B 1 173 ? 169.535 200.833 152.866 1.00 55.49  ? 173 HIS B CD2 1 
ATOM   5161  C  CE1 . HIS B 1 173 ? 169.669 201.932 154.758 1.00 55.49  ? 173 HIS B CE1 1 
ATOM   5162  N  NE2 . HIS B 1 173 ? 169.034 201.878 153.602 1.00 55.49  ? 173 HIS B NE2 1 
ATOM   5163  N  N   . SER B 1 174 ? 174.455 197.951 151.954 1.00 62.55  ? 174 SER B N   1 
ATOM   5164  C  CA  . SER B 1 174 ? 175.320 196.778 151.836 1.00 62.55  ? 174 SER B CA  1 
ATOM   5165  C  C   . SER B 1 174 ? 174.529 195.491 152.078 1.00 62.55  ? 174 SER B C   1 
ATOM   5166  O  O   . SER B 1 174 ? 174.691 194.803 153.087 1.00 62.55  ? 174 SER B O   1 
ATOM   5167  C  CB  . SER B 1 174 ? 176.518 196.884 152.787 1.00 62.55  ? 174 SER B CB  1 
ATOM   5168  O  OG  . SER B 1 174 ? 177.346 197.979 152.439 1.00 62.55  ? 174 SER B OG  1 
ATOM   5169  N  N   . ASP B 1 175 ? 173.657 195.180 151.120 1.00 60.04  ? 175 ASP B N   1 
ATOM   5170  C  CA  . ASP B 1 175 ? 172.779 194.014 151.188 1.00 60.04  ? 175 ASP B CA  1 
ATOM   5171  C  C   . ASP B 1 175 ? 172.858 193.291 149.851 1.00 60.04  ? 175 ASP B C   1 
ATOM   5172  O  O   . ASP B 1 175 ? 172.333 193.774 148.840 1.00 60.04  ? 175 ASP B O   1 
ATOM   5173  C  CB  . ASP B 1 175 ? 171.346 194.423 151.521 1.00 60.04  ? 175 ASP B CB  1 
ATOM   5174  C  CG  . ASP B 1 175 ? 170.461 193.241 151.845 1.00 60.04  ? 175 ASP B CG  1 
ATOM   5175  O  OD1 . ASP B 1 175 ? 170.944 192.093 151.786 1.00 60.04  ? 175 ASP B OD1 1 
ATOM   5176  O  OD2 . ASP B 1 175 ? 169.275 193.457 152.162 1.00 60.04  ? 175 ASP B OD2 1 
ATOM   5177  N  N   . PRO B 1 176 ? 173.515 192.131 149.805 1.00 64.75  ? 176 PRO B N   1 
ATOM   5178  C  CA  . PRO B 1 176 ? 173.635 191.416 148.525 1.00 64.75  ? 176 PRO B CA  1 
ATOM   5179  C  C   . PRO B 1 176 ? 172.378 190.665 148.124 1.00 64.75  ? 176 PRO B C   1 
ATOM   5180  O  O   . PRO B 1 176 ? 172.123 190.504 146.924 1.00 64.75  ? 176 PRO B O   1 
ATOM   5181  C  CB  . PRO B 1 176 ? 174.806 190.460 148.776 1.00 64.75  ? 176 PRO B CB  1 
ATOM   5182  C  CG  . PRO B 1 176 ? 174.764 190.212 150.245 1.00 64.75  ? 176 PRO B CG  1 
ATOM   5183  C  CD  . PRO B 1 176 ? 174.299 191.494 150.876 1.00 64.75  ? 176 PRO B CD  1 
ATOM   5184  N  N   . GLU B 1 177 ? 171.582 190.199 149.088 1.00 66.27  ? 177 GLU B N   1 
ATOM   5185  C  CA  . GLU B 1 177 ? 170.388 189.425 148.760 1.00 66.27  ? 177 GLU B CA  1 
ATOM   5186  C  C   . GLU B 1 177 ? 169.356 190.280 148.036 1.00 66.27  ? 177 GLU B C   1 
ATOM   5187  O  O   . GLU B 1 177 ? 168.937 189.955 146.917 1.00 66.27  ? 177 GLU B O   1 
ATOM   5188  C  CB  . GLU B 1 177 ? 169.786 188.831 150.034 1.00 66.27  ? 177 GLU B CB  1 
ATOM   5189  C  CG  . GLU B 1 177 ? 170.676 187.824 150.742 1.00 66.27  ? 177 GLU B CG  1 
ATOM   5190  C  CD  . GLU B 1 177 ? 170.870 186.551 149.945 1.00 66.27  ? 177 GLU B CD  1 
ATOM   5191  O  OE1 . GLU B 1 177 ? 169.942 186.165 149.203 1.00 66.27  ? 177 GLU B OE1 1 
ATOM   5192  O  OE2 . GLU B 1 177 ? 171.949 185.934 150.062 1.00 66.27  ? 177 GLU B OE2 1 
ATOM   5193  N  N   . LEU B 1 178 ? 168.928 191.377 148.663 1.00 56.93  ? 178 LEU B N   1 
ATOM   5194  C  CA  . LEU B 1 178 ? 167.932 192.242 148.041 1.00 56.93  ? 178 LEU B CA  1 
ATOM   5195  C  C   . LEU B 1 178 ? 168.490 192.924 146.799 1.00 56.93  ? 178 LEU B C   1 
ATOM   5196  O  O   . LEU B 1 178 ? 167.728 193.365 145.933 1.00 56.93  ? 178 LEU B O   1 
ATOM   5197  C  CB  . LEU B 1 178 ? 167.435 193.279 149.047 1.00 56.93  ? 178 LEU B CB  1 
ATOM   5198  C  CG  . LEU B 1 178 ? 166.325 194.214 148.570 1.00 56.93  ? 178 LEU B CG  1 
ATOM   5199  C  CD1 . LEU B 1 178 ? 165.083 193.422 148.230 1.00 56.93  ? 178 LEU B CD1 1 
ATOM   5200  C  CD2 . LEU B 1 178 ? 166.022 195.261 149.616 1.00 56.93  ? 178 LEU B CD2 1 
ATOM   5201  N  N   . TYR B 1 179 ? 169.814 193.023 146.692 1.00 62.71  ? 179 TYR B N   1 
ATOM   5202  C  CA  . TYR B 1 179 ? 170.404 193.578 145.480 1.00 62.71  ? 179 TYR B CA  1 
ATOM   5203  C  C   . TYR B 1 179 ? 170.308 192.589 144.328 1.00 62.71  ? 179 TYR B C   1 
ATOM   5204  O  O   . TYR B 1 179 ? 170.020 192.975 143.190 1.00 62.71  ? 179 TYR B O   1 
ATOM   5205  C  CB  . TYR B 1 179 ? 171.856 193.965 145.731 1.00 62.71  ? 179 TYR B CB  1 
ATOM   5206  C  CG  . TYR B 1 179 ? 172.514 194.652 144.565 1.00 62.71  ? 179 TYR B CG  1 
ATOM   5207  C  CD1 . TYR B 1 179 ? 172.279 195.990 144.306 1.00 62.71  ? 179 TYR B CD1 1 
ATOM   5208  C  CD2 . TYR B 1 179 ? 173.368 193.963 143.722 1.00 62.71  ? 179 TYR B CD2 1 
ATOM   5209  C  CE1 . TYR B 1 179 ? 172.881 196.624 143.246 1.00 62.71  ? 179 TYR B CE1 1 
ATOM   5210  C  CE2 . TYR B 1 179 ? 173.973 194.590 142.656 1.00 62.71  ? 179 TYR B CE2 1 
ATOM   5211  C  CZ  . TYR B 1 179 ? 173.726 195.921 142.423 1.00 62.71  ? 179 TYR B CZ  1 
ATOM   5212  O  OH  . TYR B 1 179 ? 174.326 196.553 141.361 1.00 62.71  ? 179 TYR B OH  1 
ATOM   5213  N  N   . THR B 1 180 ? 170.545 191.305 144.603 1.00 65.51  ? 180 THR B N   1 
ATOM   5214  C  CA  . THR B 1 180 ? 170.394 190.292 143.566 1.00 65.51  ? 180 THR B CA  1 
ATOM   5215  C  C   . THR B 1 180 ? 168.934 190.135 143.160 1.00 65.51  ? 180 THR B C   1 
ATOM   5216  O  O   . THR B 1 180 ? 168.619 190.042 141.967 1.00 65.51  ? 180 THR B O   1 
ATOM   5217  C  CB  . THR B 1 180 ? 170.958 188.957 144.046 1.00 65.51  ? 180 THR B CB  1 
ATOM   5218  O  OG1 . THR B 1 180 ? 172.351 189.107 144.347 1.00 65.51  ? 180 THR B OG1 1 
ATOM   5219  C  CG2 . THR B 1 180 ? 170.786 187.898 142.974 1.00 65.51  ? 180 THR B CG2 1 
ATOM   5220  N  N   . ALA B 1 181 ? 168.027 190.106 144.140 1.00 59.78  ? 181 ALA B N   1 
ATOM   5221  C  CA  . ALA B 1 181 ? 166.607 189.990 143.823 1.00 59.78  ? 181 ALA B CA  1 
ATOM   5222  C  C   . ALA B 1 181 ? 166.090 191.223 143.098 1.00 59.78  ? 181 ALA B C   1 
ATOM   5223  O  O   . ALA B 1 181 ? 165.277 191.102 142.175 1.00 59.78  ? 181 ALA B O   1 
ATOM   5224  C  CB  . ALA B 1 181 ? 165.801 189.750 145.096 1.00 59.78  ? 181 ALA B CB  1 
ATOM   5225  N  N   . ALA B 1 182 ? 166.537 192.409 143.499 1.00 59.61  ? 182 ALA B N   1 
ATOM   5226  C  CA  . ALA B 1 182 ? 166.147 193.653 142.853 1.00 59.61  ? 182 ALA B CA  1 
ATOM   5227  C  C   . ALA B 1 182 ? 166.885 193.891 141.548 1.00 59.61  ? 182 ALA B C   1 
ATOM   5228  O  O   . ALA B 1 182 ? 166.558 194.843 140.834 1.00 59.61  ? 182 ALA B O   1 
ATOM   5229  C  CB  . ALA B 1 182 ? 166.382 194.838 143.793 1.00 59.61  ? 182 ALA B CB  1 
ATOM   5230  N  N   . LYS B 1 183 ? 167.872 193.059 141.227 1.00 67.18  ? 183 LYS B N   1 
ATOM   5231  C  CA  . LYS B 1 183 ? 168.582 193.138 139.959 1.00 67.18  ? 183 LYS B CA  1 
ATOM   5232  C  C   . LYS B 1 183 ? 168.070 192.140 138.936 1.00 67.18  ? 183 LYS B C   1 
ATOM   5233  O  O   . LYS B 1 183 ? 168.075 192.437 137.737 1.00 67.18  ? 183 LYS B O   1 
ATOM   5234  C  CB  . LYS B 1 183 ? 170.081 192.917 140.188 1.00 67.18  ? 183 LYS B CB  1 
ATOM   5235  C  CG  . LYS B 1 183 ? 170.941 192.994 138.946 1.00 67.18  ? 183 LYS B CG  1 
ATOM   5236  C  CD  . LYS B 1 183 ? 172.409 192.939 139.324 1.00 67.18  ? 183 LYS B CD  1 
ATOM   5237  C  CE  . LYS B 1 183 ? 172.802 191.553 139.802 1.00 67.18  ? 183 LYS B CE  1 
ATOM   5238  N  NZ  . LYS B 1 183 ? 174.252 191.456 140.125 1.00 67.18  ? 183 LYS B NZ  1 
ATOM   5239  N  N   . HIS B 1 184 ? 167.613 190.971 139.390 1.00 72.16  ? 184 HIS B N   1 
ATOM   5240  C  CA  . HIS B 1 184 ? 167.036 189.989 138.479 1.00 72.16  ? 184 HIS B CA  1 
ATOM   5241  C  C   . HIS B 1 184 ? 165.824 190.556 137.751 1.00 72.16  ? 184 HIS B C   1 
ATOM   5242  O  O   . HIS B 1 184 ? 165.669 190.358 136.540 1.00 72.16  ? 184 HIS B O   1 
ATOM   5243  C  CB  . HIS B 1 184 ? 166.661 188.726 139.254 1.00 72.16  ? 184 HIS B CB  1 
ATOM   5244  C  CG  . HIS B 1 184 ? 166.175 187.606 138.390 1.00 72.16  ? 184 HIS B CG  1 
ATOM   5245  N  ND1 . HIS B 1 184 ? 164.855 187.474 138.017 1.00 72.16  ? 184 HIS B ND1 1 
ATOM   5246  C  CD2 . HIS B 1 184 ? 166.829 186.559 137.835 1.00 72.16  ? 184 HIS B CD2 1 
ATOM   5247  C  CE1 . HIS B 1 184 ? 164.718 186.397 137.264 1.00 72.16  ? 184 HIS B CE1 1 
ATOM   5248  N  NE2 . HIS B 1 184 ? 165.901 185.824 137.138 1.00 72.16  ? 184 HIS B NE2 1 
ATOM   5249  N  N   . CYS B 1 185 ? 164.961 191.281 138.466 1.00 70.00  ? 185 CYS B N   1 
ATOM   5250  C  CA  . CYS B 1 185 ? 163.754 191.813 137.842 1.00 70.00  ? 185 CYS B CA  1 
ATOM   5251  C  C   . CYS B 1 185 ? 164.075 192.933 136.861 1.00 70.00  ? 185 CYS B C   1 
ATOM   5252  O  O   . CYS B 1 185 ? 163.449 193.028 135.800 1.00 70.00  ? 185 CYS B O   1 
ATOM   5253  C  CB  . CYS B 1 185 ? 162.777 192.301 138.908 1.00 70.00  ? 185 CYS B CB  1 
ATOM   5254  S  SG  . CYS B 1 185 ? 161.236 192.954 138.233 1.00 70.00  ? 185 CYS B SG  1 
ATOM   5255  N  N   . ALA B 1 186 ? 165.040 193.794 137.194 1.00 69.71  ? 186 ALA B N   1 
ATOM   5256  C  CA  . ALA B 1 186 ? 165.453 194.827 136.248 1.00 69.71  ? 186 ALA B CA  1 
ATOM   5257  C  C   . ALA B 1 186 ? 166.155 194.226 135.043 1.00 69.71  ? 186 ALA B C   1 
ATOM   5258  O  O   . ALA B 1 186 ? 166.158 194.826 133.964 1.00 69.71  ? 186 ALA B O   1 
ATOM   5259  C  CB  . ALA B 1 186 ? 166.365 195.845 136.928 1.00 69.71  ? 186 ALA B CB  1 
ATOM   5260  N  N   . LYS B 1 187 ? 166.758 193.049 135.208 1.00 76.95  ? 187 LYS B N   1 
ATOM   5261  C  CA  . LYS B 1 187 ? 167.379 192.372 134.076 1.00 76.95  ? 187 LYS B CA  1 
ATOM   5262  C  C   . LYS B 1 187 ? 166.333 191.765 133.152 1.00 76.95  ? 187 LYS B C   1 
ATOM   5263  O  O   . LYS B 1 187 ? 166.367 191.988 131.937 1.00 76.95  ? 187 LYS B O   1 
ATOM   5264  C  CB  . LYS B 1 187 ? 168.337 191.296 134.578 1.00 76.95  ? 187 LYS B CB  1 
ATOM   5265  C  CG  . LYS B 1 187 ? 169.059 190.557 133.483 1.00 76.95  ? 187 LYS B CG  1 
ATOM   5266  C  CD  . LYS B 1 187 ? 170.053 189.574 134.061 1.00 76.95  ? 187 LYS B CD  1 
ATOM   5267  C  CE  . LYS B 1 187 ? 169.402 188.236 134.357 1.00 76.95  ? 187 LYS B CE  1 
ATOM   5268  N  NZ  . LYS B 1 187 ? 168.748 188.213 135.692 1.00 76.95  ? 187 LYS B NZ  1 
ATOM   5269  N  N   . THR B 1 188 ? 165.394 190.999 133.703 1.00 79.61  ? 188 THR B N   1 
ATOM   5270  C  CA  . THR B 1 188 ? 164.376 190.334 132.899 1.00 79.61  ? 188 THR B CA  1 
ATOM   5271  C  C   . THR B 1 188 ? 163.224 191.252 132.507 1.00 79.61  ? 188 THR B C   1 
ATOM   5272  O  O   . THR B 1 188 ? 162.207 190.762 132.007 1.00 79.61  ? 188 THR B O   1 
ATOM   5273  C  CB  . THR B 1 188 ? 163.826 189.112 133.640 1.00 79.61  ? 188 THR B CB  1 
ATOM   5274  O  OG1 . THR B 1 188 ? 162.952 188.381 132.771 1.00 79.61  ? 188 THR B OG1 1 
ATOM   5275  C  CG2 . THR B 1 188 ? 163.056 189.538 134.876 1.00 79.61  ? 188 THR B CG2 1 
ATOM   5276  N  N   . HIS B 1 189 ? 163.352 192.562 132.721 1.00 81.73  ? 189 HIS B N   1 
ATOM   5277  C  CA  . HIS B 1 189 ? 162.376 193.539 132.250 1.00 81.73  ? 189 HIS B CA  1 
ATOM   5278  C  C   . HIS B 1 189 ? 163.069 194.789 131.725 1.00 81.73  ? 189 HIS B C   1 
ATOM   5279  O  O   . HIS B 1 189 ? 162.634 195.909 132.003 1.00 81.73  ? 189 HIS B O   1 
ATOM   5280  C  CB  . HIS B 1 189 ? 161.381 193.912 133.350 1.00 81.73  ? 189 HIS B CB  1 
ATOM   5281  C  CG  . HIS B 1 189 ? 160.458 192.800 133.740 1.00 81.73  ? 189 HIS B CG  1 
ATOM   5282  N  ND1 . HIS B 1 189 ? 160.755 191.902 134.742 1.00 81.73  ? 189 HIS B ND1 1 
ATOM   5283  C  CD2 . HIS B 1 189 ? 159.240 192.446 133.266 1.00 81.73  ? 189 HIS B CD2 1 
ATOM   5284  C  CE1 . HIS B 1 189 ? 159.761 191.041 134.867 1.00 81.73  ? 189 HIS B CE1 1 
ATOM   5285  N  NE2 . HIS B 1 189 ? 158.830 191.348 133.983 1.00 81.73  ? 189 HIS B NE2 1 
ATOM   5286  N  N   . LEU B 1 190 ? 164.148 194.615 130.962 1.00 90.18  ? 190 LEU B N   1 
ATOM   5287  C  CA  . LEU B 1 190 ? 164.932 195.751 130.494 1.00 90.18  ? 190 LEU B CA  1 
ATOM   5288  C  C   . LEU B 1 190 ? 164.321 196.426 129.272 1.00 90.18  ? 190 LEU B C   1 
ATOM   5289  O  O   . LEU B 1 190 ? 164.670 197.575 128.978 1.00 90.18  ? 190 LEU B O   1 
ATOM   5290  C  CB  . LEU B 1 190 ? 166.364 195.301 130.188 1.00 90.18  ? 190 LEU B CB  1 
ATOM   5291  C  CG  . LEU B 1 190 ? 167.401 196.368 129.834 1.00 90.18  ? 190 LEU B CG  1 
ATOM   5292  C  CD1 . LEU B 1 190 ? 167.579 197.330 130.992 1.00 90.18  ? 190 LEU B CD1 1 
ATOM   5293  C  CD2 . LEU B 1 190 ? 168.725 195.725 129.469 1.00 90.18  ? 190 LEU B CD2 1 
ATOM   5294  N  N   . ALA B 1 191 ? 163.413 195.751 128.563 1.00 94.01  ? 191 ALA B N   1 
ATOM   5295  C  CA  . ALA B 1 191 ? 162.807 196.355 127.381 1.00 94.01  ? 191 ALA B CA  1 
ATOM   5296  C  C   . ALA B 1 191 ? 161.965 197.569 127.748 1.00 94.01  ? 191 ALA B C   1 
ATOM   5297  O  O   . ALA B 1 191 ? 162.238 198.684 127.289 1.00 94.01  ? 191 ALA B O   1 
ATOM   5298  C  CB  . ALA B 1 191 ? 161.962 195.323 126.635 1.00 94.01  ? 191 ALA B CB  1 
ATOM   5299  N  N   . GLN B 1 192 ? 160.939 197.376 128.575 1.00 96.02  ? 192 GLN B N   1 
ATOM   5300  C  CA  . GLN B 1 192 ? 160.064 198.462 128.996 1.00 96.02  ? 192 GLN B CA  1 
ATOM   5301  C  C   . GLN B 1 192 ? 160.660 199.301 130.117 1.00 96.02  ? 192 GLN B C   1 
ATOM   5302  O  O   . GLN B 1 192 ? 159.914 199.968 130.840 1.00 96.02  ? 192 GLN B O   1 
ATOM   5303  C  CB  . GLN B 1 192 ? 158.700 197.908 129.426 1.00 96.02  ? 192 GLN B CB  1 
ATOM   5304  C  CG  . GLN B 1 192 ? 158.739 196.983 130.630 1.00 96.02  ? 192 GLN B CG  1 
ATOM   5305  C  CD  . GLN B 1 192 ? 157.372 196.422 130.970 1.00 96.02  ? 192 GLN B CD  1 
ATOM   5306  O  OE1 . GLN B 1 192 ? 156.373 196.772 130.344 1.00 96.02  ? 192 GLN B OE1 1 
ATOM   5307  N  NE2 . GLN B 1 192 ? 157.323 195.544 131.964 1.00 96.02  ? 192 GLN B NE2 1 
ATOM   5308  N  N   . LEU B 1 193 ? 161.980 199.288 130.273 1.00 93.40  ? 193 LEU B N   1 
ATOM   5309  C  CA  . LEU B 1 193 ? 162.670 200.093 131.268 1.00 93.40  ? 193 LEU B CA  1 
ATOM   5310  C  C   . LEU B 1 193 ? 163.603 201.116 130.634 1.00 93.40  ? 193 LEU B C   1 
ATOM   5311  O  O   . LEU B 1 193 ? 164.073 202.024 131.327 1.00 93.40  ? 193 LEU B O   1 
ATOM   5312  C  CB  . LEU B 1 193 ? 163.453 199.175 132.216 1.00 93.40  ? 193 LEU B CB  1 
ATOM   5313  C  CG  . LEU B 1 193 ? 164.130 199.755 133.457 1.00 93.40  ? 193 LEU B CG  1 
ATOM   5314  C  CD1 . LEU B 1 193 ? 163.093 200.332 134.403 1.00 93.40  ? 193 LEU B CD1 1 
ATOM   5315  C  CD2 . LEU B 1 193 ? 164.949 198.686 134.151 1.00 93.40  ? 193 LEU B CD2 1 
ATOM   5316  N  N   . GLN B 1 194 ? 163.854 201.002 129.326 1.00 101.68 ? 194 GLN B N   1 
ATOM   5317  C  CA  . GLN B 1 194 ? 164.815 201.868 128.650 1.00 101.68 ? 194 GLN B CA  1 
ATOM   5318  C  C   . GLN B 1 194 ? 164.407 203.333 128.706 1.00 101.68 ? 194 GLN B C   1 
ATOM   5319  O  O   . GLN B 1 194 ? 165.267 204.209 128.853 1.00 101.68 ? 194 GLN B O   1 
ATOM   5320  C  CB  . GLN B 1 194 ? 164.961 201.441 127.191 1.00 101.68 ? 194 GLN B CB  1 
ATOM   5321  C  CG  . GLN B 1 194 ? 165.486 200.034 126.986 1.00 101.68 ? 194 GLN B CG  1 
ATOM   5322  C  CD  . GLN B 1 194 ? 165.526 199.649 125.522 1.00 101.68 ? 194 GLN B CD  1 
ATOM   5323  O  OE1 . GLN B 1 194 ? 165.151 200.435 124.653 1.00 101.68 ? 194 GLN B OE1 1 
ATOM   5324  N  NE2 . GLN B 1 194 ? 165.955 198.426 125.243 1.00 101.68 ? 194 GLN B NE2 1 
ATOM   5325  N  N   . ASN B 1 195 ? 163.113 203.620 128.582 1.00 103.40 ? 195 ASN B N   1 
ATOM   5326  C  CA  . ASN B 1 195 ? 162.630 204.986 128.451 1.00 103.40 ? 195 ASN B CA  1 
ATOM   5327  C  C   . ASN B 1 195 ? 162.308 205.647 129.784 1.00 103.40 ? 195 ASN B C   1 
ATOM   5328  O  O   . ASN B 1 195 ? 162.046 206.854 129.808 1.00 103.40 ? 195 ASN B O   1 
ATOM   5329  C  CB  . ASN B 1 195 ? 161.389 205.016 127.553 1.00 103.40 ? 195 ASN B CB  1 
ATOM   5330  C  CG  . ASN B 1 195 ? 161.714 204.716 126.103 1.00 103.40 ? 195 ASN B CG  1 
ATOM   5331  O  OD1 . ASN B 1 195 ? 162.709 205.202 125.566 1.00 103.40 ? 195 ASN B OD1 1 
ATOM   5332  N  ND2 . ASN B 1 195 ? 160.877 203.909 125.462 1.00 103.40 ? 195 ASN B ND2 1 
ATOM   5333  N  N   . THR B 1 196 ? 162.316 204.897 130.883 1.00 100.63 ? 196 THR B N   1 
ATOM   5334  C  CA  . THR B 1 196 ? 162.081 205.500 132.187 1.00 100.63 ? 196 THR B CA  1 
ATOM   5335  C  C   . THR B 1 196 ? 163.223 206.444 132.542 1.00 100.63 ? 196 THR B C   1 
ATOM   5336  O  O   . THR B 1 196 ? 164.392 206.163 132.267 1.00 100.63 ? 196 THR B O   1 
ATOM   5337  C  CB  . THR B 1 196 ? 161.936 204.418 133.258 1.00 100.63 ? 196 THR B CB  1 
ATOM   5338  O  OG1 . THR B 1 196 ? 163.133 203.632 133.310 1.00 100.63 ? 196 THR B OG1 1 
ATOM   5339  C  CG2 . THR B 1 196 ? 160.756 203.516 132.944 1.00 100.63 ? 196 THR B CG2 1 
ATOM   5340  N  N   . GLU B 1 197 ? 162.877 207.575 133.162 1.00 102.43 ? 197 GLU B N   1 
ATOM   5341  C  CA  . GLU B 1 197 ? 163.881 208.596 133.443 1.00 102.43 ? 197 GLU B CA  1 
ATOM   5342  C  C   . GLU B 1 197 ? 164.846 208.166 134.540 1.00 102.43 ? 197 GLU B C   1 
ATOM   5343  O  O   . GLU B 1 197 ? 165.809 208.885 134.829 1.00 102.43 ? 197 GLU B O   1 
ATOM   5344  C  CB  . GLU B 1 197 ? 163.203 209.913 133.822 1.00 102.43 ? 197 GLU B CB  1 
ATOM   5345  C  CG  . GLU B 1 197 ? 162.472 210.583 132.672 1.00 102.43 ? 197 GLU B CG  1 
ATOM   5346  C  CD  . GLU B 1 197 ? 163.417 211.076 131.591 1.00 102.43 ? 197 GLU B CD  1 
ATOM   5347  O  OE1 . GLU B 1 197 ? 164.559 211.459 131.924 1.00 102.43 ? 197 GLU B OE1 1 
ATOM   5348  O  OE2 . GLU B 1 197 ? 163.017 211.083 130.408 1.00 102.43 ? 197 GLU B OE2 1 
ATOM   5349  N  N   . GLU B 1 198 ? 164.611 207.009 135.161 1.00 97.16  ? 198 GLU B N   1 
ATOM   5350  C  CA  . GLU B 1 198 ? 165.560 206.503 136.147 1.00 97.16  ? 198 GLU B CA  1 
ATOM   5351  C  C   . GLU B 1 198 ? 166.658 205.685 135.480 1.00 97.16  ? 198 GLU B C   1 
ATOM   5352  O  O   . GLU B 1 198 ? 167.800 205.662 135.953 1.00 97.16  ? 198 GLU B O   1 
ATOM   5353  C  CB  . GLU B 1 198 ? 164.831 205.670 137.200 1.00 97.16  ? 198 GLU B CB  1 
ATOM   5354  C  CG  . GLU B 1 198 ? 165.735 205.107 138.285 1.00 97.16  ? 198 GLU B CG  1 
ATOM   5355  C  CD  . GLU B 1 198 ? 166.372 206.185 139.140 1.00 97.16  ? 198 GLU B CD  1 
ATOM   5356  O  OE1 . GLU B 1 198 ? 165.786 207.282 139.253 1.00 97.16  ? 198 GLU B OE1 1 
ATOM   5357  O  OE2 . GLU B 1 198 ? 167.459 205.935 139.702 1.00 97.16  ? 198 GLU B OE2 1 
ATOM   5358  N  N   . PHE B 1 199 ? 166.336 205.017 134.371 1.00 97.74  ? 199 PHE B N   1 
ATOM   5359  C  CA  . PHE B 1 199 ? 167.341 204.220 133.676 1.00 97.74  ? 199 PHE B CA  1 
ATOM   5360  C  C   . PHE B 1 199 ? 168.331 205.106 132.930 1.00 97.74  ? 199 PHE B C   1 
ATOM   5361  O  O   . PHE B 1 199 ? 169.395 204.641 132.507 1.00 97.74  ? 199 PHE B O   1 
ATOM   5362  C  CB  . PHE B 1 199 ? 166.665 203.244 132.716 1.00 97.74  ? 199 PHE B CB  1 
ATOM   5363  C  CG  . PHE B 1 199 ? 167.622 202.333 132.006 1.00 97.74  ? 199 PHE B CG  1 
ATOM   5364  C  CD1 . PHE B 1 199 ? 168.205 201.273 132.673 1.00 97.74  ? 199 PHE B CD1 1 
ATOM   5365  C  CD2 . PHE B 1 199 ? 167.938 202.536 130.675 1.00 97.74  ? 199 PHE B CD2 1 
ATOM   5366  C  CE1 . PHE B 1 199 ? 169.085 200.431 132.028 1.00 97.74  ? 199 PHE B CE1 1 
ATOM   5367  C  CE2 . PHE B 1 199 ? 168.820 201.696 130.025 1.00 97.74  ? 199 PHE B CE2 1 
ATOM   5368  C  CZ  . PHE B 1 199 ? 169.394 200.642 130.703 1.00 97.74  ? 199 PHE B CZ  1 
ATOM   5369  N  N   . LEU B 1 200 ? 168.002 206.387 132.762 1.00 102.63 ? 200 LEU B N   1 
ATOM   5370  C  CA  . LEU B 1 200 ? 168.919 207.290 132.076 1.00 102.63 ? 200 LEU B CA  1 
ATOM   5371  C  C   . LEU B 1 200 ? 169.885 207.956 133.047 1.00 102.63 ? 200 LEU B C   1 
ATOM   5372  O  O   . LEU B 1 200 ? 170.963 208.399 132.638 1.00 102.63 ? 200 LEU B O   1 
ATOM   5373  C  CB  . LEU B 1 200 ? 168.132 208.338 131.292 1.00 102.63 ? 200 LEU B CB  1 
ATOM   5374  C  CG  . LEU B 1 200 ? 167.305 207.784 130.129 1.00 102.63 ? 200 LEU B CG  1 
ATOM   5375  C  CD1 . LEU B 1 200 ? 166.465 208.878 129.494 1.00 102.63 ? 200 LEU B CD1 1 
ATOM   5376  C  CD2 . LEU B 1 200 ? 168.203 207.124 129.096 1.00 102.63 ? 200 LEU B CD2 1 
ATOM   5377  N  N   . HIS B 1 201 ? 169.524 208.033 134.326 1.00 99.16  ? 201 HIS B N   1 
ATOM   5378  C  CA  . HIS B 1 201 ? 170.397 208.578 135.357 1.00 99.16  ? 201 HIS B CA  1 
ATOM   5379  C  C   . HIS B 1 201 ? 171.171 207.502 136.104 1.00 99.16  ? 201 HIS B C   1 
ATOM   5380  O  O   . HIS B 1 201 ? 171.932 207.829 137.021 1.00 99.16  ? 201 HIS B O   1 
ATOM   5381  C  CB  . HIS B 1 201 ? 169.584 209.398 136.364 1.00 99.16  ? 201 HIS B CB  1 
ATOM   5382  C  CG  . HIS B 1 201 ? 168.970 210.634 135.787 1.00 99.16  ? 201 HIS B CG  1 
ATOM   5383  N  ND1 . HIS B 1 201 ? 167.728 210.639 135.192 1.00 99.16  ? 201 HIS B ND1 1 
ATOM   5384  C  CD2 . HIS B 1 201 ? 169.424 211.908 135.723 1.00 99.16  ? 201 HIS B CD2 1 
ATOM   5385  C  CE1 . HIS B 1 201 ? 167.444 211.862 134.781 1.00 99.16  ? 201 HIS B CE1 1 
ATOM   5386  N  NE2 . HIS B 1 201 ? 168.456 212.651 135.091 1.00 99.16  ? 201 HIS B NE2 1 
ATOM   5387  N  N   . LEU B 1 202 ? 170.997 206.243 135.737 1.00 91.57  ? 202 LEU B N   1 
ATOM   5388  C  CA  . LEU B 1 202 ? 171.595 205.150 136.489 1.00 91.57  ? 202 LEU B CA  1 
ATOM   5389  C  C   . LEU B 1 202 ? 173.110 205.166 136.311 1.00 91.57  ? 202 LEU B C   1 
ATOM   5390  O  O   . LEU B 1 202 ? 173.593 205.238 135.175 1.00 91.57  ? 202 LEU B O   1 
ATOM   5391  C  CB  . LEU B 1 202 ? 171.005 203.825 136.016 1.00 91.57  ? 202 LEU B CB  1 
ATOM   5392  C  CG  . LEU B 1 202 ? 171.302 202.560 136.811 1.00 91.57  ? 202 LEU B CG  1 
ATOM   5393  C  CD1 . LEU B 1 202 ? 170.703 202.677 138.198 1.00 91.57  ? 202 LEU B CD1 1 
ATOM   5394  C  CD2 . LEU B 1 202 ? 170.739 201.353 136.090 1.00 91.57  ? 202 LEU B CD2 1 
ATOM   5395  N  N   . PRO B 1 203 ? 173.893 205.107 137.397 1.00 93.04  ? 203 PRO B N   1 
ATOM   5396  C  CA  . PRO B 1 203 ? 175.353 205.215 137.265 1.00 93.04  ? 203 PRO B CA  1 
ATOM   5397  C  C   . PRO B 1 203 ? 175.992 204.010 136.593 1.00 93.04  ? 203 PRO B C   1 
ATOM   5398  O  O   . PRO B 1 203 ? 175.296 203.095 136.142 1.00 93.04  ? 203 PRO B O   1 
ATOM   5399  C  CB  . PRO B 1 203 ? 175.823 205.363 138.717 1.00 93.04  ? 203 PRO B CB  1 
ATOM   5400  C  CG  . PRO B 1 203 ? 174.764 204.716 139.520 1.00 93.04  ? 203 PRO B CG  1 
ATOM   5401  C  CD  . PRO B 1 203 ? 173.474 204.986 138.804 1.00 93.04  ? 203 PRO B CD  1 
ATOM   5402  N  N   . HIS B 1 204 ? 177.325 203.996 136.536 1.00 98.48  ? 204 HIS B N   1 
ATOM   5403  C  CA  . HIS B 1 204 ? 178.025 203.007 135.720 1.00 98.48  ? 204 HIS B CA  1 
ATOM   5404  C  C   . HIS B 1 204 ? 178.015 201.629 136.373 1.00 98.48  ? 204 HIS B C   1 
ATOM   5405  O  O   . HIS B 1 204 ? 177.842 200.613 135.690 1.00 98.48  ? 204 HIS B O   1 
ATOM   5406  C  CB  . HIS B 1 204 ? 179.460 203.463 135.458 1.00 98.48  ? 204 HIS B CB  1 
ATOM   5407  C  CG  . HIS B 1 204 ? 180.191 202.611 134.467 1.00 98.48  ? 204 HIS B CG  1 
ATOM   5408  N  ND1 . HIS B 1 204 ? 181.560 202.658 134.313 1.00 98.48  ? 204 HIS B ND1 1 
ATOM   5409  C  CD2 . HIS B 1 204 ? 179.743 201.699 133.573 1.00 98.48  ? 204 HIS B CD2 1 
ATOM   5410  C  CE1 . HIS B 1 204 ? 181.925 201.805 133.372 1.00 98.48  ? 204 HIS B CE1 1 
ATOM   5411  N  NE2 . HIS B 1 204 ? 180.841 201.211 132.907 1.00 98.48  ? 204 HIS B NE2 1 
ATOM   5412  N  N   . ARG B 1 205 ? 178.215 201.570 137.691 1.00 87.95  ? 205 ARG B N   1 
ATOM   5413  C  CA  . ARG B 1 205 ? 178.305 200.274 138.359 1.00 87.95  ? 205 ARG B CA  1 
ATOM   5414  C  C   . ARG B 1 205 ? 176.990 199.511 138.277 1.00 87.95  ? 205 ARG B C   1 
ATOM   5415  O  O   . ARG B 1 205 ? 176.981 198.304 138.002 1.00 87.95  ? 205 ARG B O   1 
ATOM   5416  C  CB  . ARG B 1 205 ? 178.719 200.459 139.817 1.00 87.95  ? 205 ARG B CB  1 
ATOM   5417  C  CG  . ARG B 1 205 ? 178.939 199.151 140.557 1.00 87.95  ? 205 ARG B CG  1 
ATOM   5418  C  CD  . ARG B 1 205 ? 179.381 199.396 141.987 1.00 87.95  ? 205 ARG B CD  1 
ATOM   5419  N  NE  . ARG B 1 205 ? 178.341 200.057 142.768 1.00 87.95  ? 205 ARG B NE  1 
ATOM   5420  C  CZ  . ARG B 1 205 ? 178.433 201.300 143.228 1.00 87.95  ? 205 ARG B CZ  1 
ATOM   5421  N  NH1 . ARG B 1 205 ? 179.518 202.019 142.980 1.00 87.95  ? 205 ARG B NH1 1 
ATOM   5422  N  NH2 . ARG B 1 205 ? 177.440 201.825 143.931 1.00 87.95  ? 205 ARG B NH2 1 
ATOM   5423  N  N   . LEU B 1 206 ? 175.870 200.197 138.510 1.00 83.15  ? 206 LEU B N   1 
ATOM   5424  C  CA  . LEU B 1 206 ? 174.573 199.530 138.503 1.00 83.15  ? 206 LEU B CA  1 
ATOM   5425  C  C   . LEU B 1 206 ? 174.256 198.969 137.122 1.00 83.15  ? 206 LEU B C   1 
ATOM   5426  O  O   . LEU B 1 206 ? 173.888 197.795 136.981 1.00 83.15  ? 206 LEU B O   1 
ATOM   5427  C  CB  . LEU B 1 206 ? 173.480 200.501 138.955 1.00 83.15  ? 206 LEU B CB  1 
ATOM   5428  C  CG  . LEU B 1 206 ? 173.274 200.753 140.454 1.00 83.15  ? 206 LEU B CG  1 
ATOM   5429  C  CD1 . LEU B 1 206 ? 172.944 199.462 141.173 1.00 83.15  ? 206 LEU B CD1 1 
ATOM   5430  C  CD2 . LEU B 1 206 ? 174.467 201.436 141.100 1.00 83.15  ? 206 LEU B CD2 1 
ATOM   5431  N  N   . LEU B 1 207 ? 174.399 199.798 136.084 1.00 87.44  ? 207 LEU B N   1 
ATOM   5432  C  CA  . LEU B 1 207 ? 174.164 199.326 134.724 1.00 87.44  ? 207 LEU B CA  1 
ATOM   5433  C  C   . LEU B 1 207 ? 175.123 198.201 134.360 1.00 87.44  ? 207 LEU B C   1 
ATOM   5434  O  O   . LEU B 1 207 ? 174.747 197.261 133.652 1.00 87.44  ? 207 LEU B O   1 
ATOM   5435  C  CB  . LEU B 1 207 ? 174.295 200.479 133.733 1.00 87.44  ? 207 LEU B CB  1 
ATOM   5436  C  CG  . LEU B 1 207 ? 174.031 200.100 132.277 1.00 87.44  ? 207 LEU B CG  1 
ATOM   5437  C  CD1 . LEU B 1 207 ? 172.607 199.623 132.101 1.00 87.44  ? 207 LEU B CD1 1 
ATOM   5438  C  CD2 . LEU B 1 207 ? 174.307 201.273 131.373 1.00 87.44  ? 207 LEU B CD2 1 
ATOM   5439  N  N   . THR B 1 208 ? 176.366 198.279 134.837 1.00 87.03  ? 208 THR B N   1 
ATOM   5440  C  CA  . THR B 1 208 ? 177.314 197.196 134.602 1.00 87.03  ? 208 THR B CA  1 
ATOM   5441  C  C   . THR B 1 208 ? 176.830 195.903 135.245 1.00 87.03  ? 208 THR B C   1 
ATOM   5442  O  O   . THR B 1 208 ? 177.056 194.811 134.710 1.00 87.03  ? 208 THR B O   1 
ATOM   5443  C  CB  . THR B 1 208 ? 178.693 197.580 135.141 1.00 87.03  ? 208 THR B CB  1 
ATOM   5444  O  OG1 . THR B 1 208 ? 179.129 198.793 134.517 1.00 87.03  ? 208 THR B OG1 1 
ATOM   5445  C  CG2 . THR B 1 208 ? 179.707 196.486 134.851 1.00 87.03  ? 208 THR B CG2 1 
ATOM   5446  N  N   . ASP B 1 209 ? 176.145 196.008 136.386 1.00 83.56  ? 209 ASP B N   1 
ATOM   5447  C  CA  . ASP B 1 209 ? 175.659 194.809 137.061 1.00 83.56  ? 209 ASP B CA  1 
ATOM   5448  C  C   . ASP B 1 209 ? 174.422 194.240 136.375 1.00 83.56  ? 209 ASP B C   1 
ATOM   5449  O  O   . ASP B 1 209 ? 174.256 193.017 136.306 1.00 83.56  ? 209 ASP B O   1 
ATOM   5450  C  CB  . ASP B 1 209 ? 175.365 195.112 138.528 1.00 83.56  ? 209 ASP B CB  1 
ATOM   5451  C  CG  . ASP B 1 209 ? 176.623 195.346 139.335 1.00 83.56  ? 209 ASP B CG  1 
ATOM   5452  O  OD1 . ASP B 1 209 ? 177.675 194.779 138.972 1.00 83.56  ? 209 ASP B OD1 1 
ATOM   5453  O  OD2 . ASP B 1 209 ? 176.560 196.090 140.335 1.00 83.56  ? 209 ASP B OD2 1 
ATOM   5454  N  N   . ILE B 1 210 ? 173.540 195.101 135.863 1.00 82.63  ? 210 ILE B N   1 
ATOM   5455  C  CA  . ILE B 1 210 ? 172.327 194.579 135.239 1.00 82.63  ? 210 ILE B CA  1 
ATOM   5456  C  C   . ILE B 1 210 ? 172.603 194.116 133.815 1.00 82.63  ? 210 ILE B C   1 
ATOM   5457  O  O   . ILE B 1 210 ? 171.844 193.314 133.259 1.00 82.63  ? 210 ILE B O   1 
ATOM   5458  C  CB  . ILE B 1 210 ? 171.198 195.623 135.283 1.00 82.63  ? 210 ILE B CB  1 
ATOM   5459  C  CG1 . ILE B 1 210 ? 171.522 196.823 134.403 1.00 82.63  ? 210 ILE B CG1 1 
ATOM   5460  C  CG2 . ILE B 1 210 ? 170.995 196.107 136.692 1.00 82.63  ? 210 ILE B CG2 1 
ATOM   5461  C  CD1 . ILE B 1 210 ? 170.363 197.778 134.268 1.00 82.63  ? 210 ILE B CD1 1 
ATOM   5462  N  N   . ILE B 1 211 ? 173.682 194.602 133.202 1.00 89.87  ? 211 ILE B N   1 
ATOM   5463  C  CA  . ILE B 1 211 ? 174.042 194.167 131.857 1.00 89.87  ? 211 ILE B CA  1 
ATOM   5464  C  C   . ILE B 1 211 ? 174.937 192.938 131.906 1.00 89.87  ? 211 ILE B C   1 
ATOM   5465  O  O   . ILE B 1 211 ? 174.699 191.950 131.202 1.00 89.87  ? 211 ILE B O   1 
ATOM   5466  C  CB  . ILE B 1 211 ? 174.707 195.320 131.084 1.00 89.87  ? 211 ILE B CB  1 
ATOM   5467  C  CG1 . ILE B 1 211 ? 173.701 196.441 130.828 1.00 89.87  ? 211 ILE B CG1 1 
ATOM   5468  C  CG2 . ILE B 1 211 ? 175.307 194.821 129.791 1.00 89.87  ? 211 ILE B CG2 1 
ATOM   5469  C  CD1 . ILE B 1 211 ? 172.521 196.015 129.991 1.00 89.87  ? 211 ILE B CD1 1 
ATOM   5470  N  N   . SER B 1 212 ? 175.975 192.972 132.743 1.00 90.96  ? 212 SER B N   1 
ATOM   5471  C  CA  . SER B 1 212 ? 176.888 191.839 132.841 1.00 90.96  ? 212 SER B CA  1 
ATOM   5472  C  C   . SER B 1 212 ? 176.285 190.666 133.601 1.00 90.96  ? 212 SER B C   1 
ATOM   5473  O  O   . SER B 1 212 ? 176.956 190.095 134.467 1.00 90.96  ? 212 SER B O   1 
ATOM   5474  C  CB  . SER B 1 212 ? 178.192 192.269 133.513 1.00 90.96  ? 212 SER B CB  1 
ATOM   5475  O  OG  . SER B 1 212 ? 179.069 191.168 133.659 1.00 90.96  ? 212 SER B OG  1 
ATOM   5476  N  N   . ASP B 1 213 ? 175.043 190.289 133.293 1.00 92.60  ? 213 ASP B N   1 
ATOM   5477  C  CA  . ASP B 1 213 ? 174.394 189.195 134.001 1.00 92.60  ? 213 ASP B CA  1 
ATOM   5478  C  C   . ASP B 1 213 ? 173.667 188.252 133.049 1.00 92.60  ? 213 ASP B C   1 
ATOM   5479  O  O   . ASP B 1 213 ? 173.636 187.043 133.298 1.00 92.60  ? 213 ASP B O   1 
ATOM   5480  C  CB  . ASP B 1 213 ? 173.425 189.761 135.043 1.00 92.60  ? 213 ASP B CB  1 
ATOM   5481  C  CG  . ASP B 1 213 ? 172.948 188.717 136.039 1.00 92.60  ? 213 ASP B CG  1 
ATOM   5482  O  OD1 . ASP B 1 213 ? 173.368 187.546 135.941 1.00 92.60  ? 213 ASP B OD1 1 
ATOM   5483  O  OD2 . ASP B 1 213 ? 172.147 189.074 136.928 1.00 92.60  ? 213 ASP B OD2 1 
ATOM   5484  N  N   . GLY B 1 214 ? 173.096 188.771 131.966 1.00 93.99  ? 214 GLY B N   1 
ATOM   5485  C  CA  . GLY B 1 214 ? 172.447 187.926 130.985 1.00 93.99  ? 214 GLY B CA  1 
ATOM   5486  C  C   . GLY B 1 214 ? 171.074 188.413 130.574 1.00 93.99  ? 214 GLY B C   1 
ATOM   5487  O  O   . GLY B 1 214 ? 170.066 187.764 130.865 1.00 93.99  ? 214 GLY B O   1 
ATOM   5488  N  N   . VAL B 1 215 ? 171.020 189.554 129.894 1.00 95.28  ? 215 VAL B N   1 
ATOM   5489  C  CA  . VAL B 1 215 ? 169.752 190.115 129.437 1.00 95.28  ? 215 VAL B CA  1 
ATOM   5490  C  C   . VAL B 1 215 ? 169.240 189.277 128.271 1.00 95.28  ? 215 VAL B C   1 
ATOM   5491  O  O   . VAL B 1 215 ? 170.010 188.964 127.352 1.00 95.28  ? 215 VAL B O   1 
ATOM   5492  C  CB  . VAL B 1 215 ? 169.907 191.590 129.039 1.00 95.28  ? 215 VAL B CB  1 
ATOM   5493  C  CG1 . VAL B 1 215 ? 168.599 192.132 128.499 1.00 95.28  ? 215 VAL B CG1 1 
ATOM   5494  C  CG2 . VAL B 1 215 ? 170.380 192.411 130.222 1.00 95.28  ? 215 VAL B CG2 1 
ATOM   5495  N  N   . PRO B 1 216 ? 167.966 188.881 128.268 1.00 100.21 ? 216 PRO B N   1 
ATOM   5496  C  CA  . PRO B 1 216 ? 167.444 188.085 127.151 1.00 100.21 ? 216 PRO B CA  1 
ATOM   5497  C  C   . PRO B 1 216 ? 167.426 188.880 125.853 1.00 100.21 ? 216 PRO B C   1 
ATOM   5498  O  O   . PRO B 1 216 ? 167.473 190.112 125.851 1.00 100.21 ? 216 PRO B O   1 
ATOM   5499  C  CB  . PRO B 1 216 ? 166.024 187.727 127.604 1.00 100.21 ? 216 PRO B CB  1 
ATOM   5500  C  CG  . PRO B 1 216 ? 166.061 187.849 129.095 1.00 100.21 ? 216 PRO B CG  1 
ATOM   5501  C  CD  . PRO B 1 216 ? 166.999 188.982 129.372 1.00 100.21 ? 216 PRO B CD  1 
ATOM   5502  N  N   . CYS B 1 217 ? 167.351 188.153 124.735 1.00 103.35 ? 217 CYS B N   1 
ATOM   5503  C  CA  . CYS B 1 217 ? 167.327 188.810 123.431 1.00 103.35 ? 217 CYS B CA  1 
ATOM   5504  C  C   . CYS B 1 217 ? 166.019 189.559 123.215 1.00 103.35 ? 217 CYS B C   1 
ATOM   5505  O  O   . CYS B 1 217 ? 166.002 190.625 122.588 1.00 103.35 ? 217 CYS B O   1 
ATOM   5506  C  CB  . CYS B 1 217 ? 167.542 187.784 122.319 1.00 103.35 ? 217 CYS B CB  1 
ATOM   5507  S  SG  . CYS B 1 217 ? 166.226 186.554 122.174 1.00 103.35 ? 217 CYS B SG  1 
ATOM   5508  N  N   . SER B 1 218 ? 164.911 189.014 123.723 1.00 101.62 ? 218 SER B N   1 
ATOM   5509  C  CA  . SER B 1 218 ? 163.628 189.697 123.617 1.00 101.62 ? 218 SER B CA  1 
ATOM   5510  C  C   . SER B 1 218 ? 163.625 191.030 124.351 1.00 101.62 ? 218 SER B C   1 
ATOM   5511  O  O   . SER B 1 218 ? 162.819 191.905 124.019 1.00 101.62 ? 218 SER B O   1 
ATOM   5512  C  CB  . SER B 1 218 ? 162.509 188.803 124.155 1.00 101.62 ? 218 SER B CB  1 
ATOM   5513  O  OG  . SER B 1 218 ? 162.369 187.633 123.369 1.00 101.62 ? 218 SER B OG  1 
ATOM   5514  N  N   . GLN B 1 219 ? 164.506 191.203 125.331 1.00 97.44  ? 219 GLN B N   1 
ATOM   5515  C  CA  . GLN B 1 219 ? 164.631 192.453 126.065 1.00 97.44  ? 219 GLN B CA  1 
ATOM   5516  C  C   . GLN B 1 219 ? 165.601 193.426 125.409 1.00 97.44  ? 219 GLN B C   1 
ATOM   5517  O  O   . GLN B 1 219 ? 166.032 194.376 126.070 1.00 97.44  ? 219 GLN B O   1 
ATOM   5518  C  CB  . GLN B 1 219 ? 165.073 192.171 127.503 1.00 97.44  ? 219 GLN B CB  1 
ATOM   5519  C  CG  . GLN B 1 219 ? 164.079 191.347 128.299 1.00 97.44  ? 219 GLN B CG  1 
ATOM   5520  C  CD  . GLN B 1 219 ? 162.797 192.098 128.579 1.00 97.44  ? 219 GLN B CD  1 
ATOM   5521  O  OE1 . GLN B 1 219 ? 162.820 193.286 128.896 1.00 97.44  ? 219 GLN B OE1 1 
ATOM   5522  N  NE2 . GLN B 1 219 ? 161.668 191.411 128.459 1.00 97.44  ? 219 GLN B NE2 1 
ATOM   5523  N  N   . ASN B 1 220 ? 165.933 193.213 124.125 1.00 101.98 ? 220 ASN B N   1 
ATOM   5524  C  CA  . ASN B 1 220 ? 166.856 193.970 123.275 1.00 101.98 ? 220 ASN B CA  1 
ATOM   5525  C  C   . ASN B 1 220 ? 167.814 194.871 124.052 1.00 101.98 ? 220 ASN B C   1 
ATOM   5526  O  O   . ASN B 1 220 ? 167.582 196.079 124.183 1.00 101.98 ? 220 ASN B O   1 
ATOM   5527  C  CB  . ASN B 1 220 ? 166.064 194.768 122.227 1.00 101.98 ? 220 ASN B CB  1 
ATOM   5528  C  CG  . ASN B 1 220 ? 165.002 195.680 122.830 1.00 101.98 ? 220 ASN B CG  1 
ATOM   5529  O  OD1 . ASN B 1 220 ? 164.922 195.866 124.042 1.00 101.98 ? 220 ASN B OD1 1 
ATOM   5530  N  ND2 . ASN B 1 220 ? 164.165 196.243 121.968 1.00 101.98 ? 220 ASN B ND2 1 
ATOM   5531  N  N   . PRO B 1 221 ? 168.915 194.315 124.566 1.00 104.18 ? 221 PRO B N   1 
ATOM   5532  C  CA  . PRO B 1 221 ? 169.808 195.110 125.423 1.00 104.18 ? 221 PRO B CA  1 
ATOM   5533  C  C   . PRO B 1 221 ? 170.752 196.027 124.663 1.00 104.18 ? 221 PRO B C   1 
ATOM   5534  O  O   . PRO B 1 221 ? 171.239 197.001 125.252 1.00 104.18 ? 221 PRO B O   1 
ATOM   5535  C  CB  . PRO B 1 221 ? 170.588 194.040 126.194 1.00 104.18 ? 221 PRO B CB  1 
ATOM   5536  C  CG  . PRO B 1 221 ? 170.618 192.876 125.262 1.00 104.18 ? 221 PRO B CG  1 
ATOM   5537  C  CD  . PRO B 1 221 ? 169.309 192.897 124.517 1.00 104.18 ? 221 PRO B CD  1 
ATOM   5538  N  N   . THR B 1 222 ? 171.042 195.747 123.390 1.00 109.91 ? 222 THR B N   1 
ATOM   5539  C  CA  . THR B 1 222 ? 171.998 196.570 122.653 1.00 109.91 ? 222 THR B CA  1 
ATOM   5540  C  C   . THR B 1 222 ? 171.495 198.002 122.511 1.00 109.91 ? 222 THR B C   1 
ATOM   5541  O  O   . THR B 1 222 ? 172.214 198.962 122.817 1.00 109.91 ? 222 THR B O   1 
ATOM   5542  C  CB  . THR B 1 222 ? 172.275 195.957 121.280 1.00 109.91 ? 222 THR B CB  1 
ATOM   5543  O  OG1 . THR B 1 222 ? 172.824 194.643 121.443 1.00 109.91 ? 222 THR B OG1 1 
ATOM   5544  C  CG2 . THR B 1 222 ? 173.260 196.819 120.503 1.00 109.91 ? 222 THR B CG2 1 
ATOM   5545  N  N   . GLU B 1 223 ? 170.250 198.167 122.058 1.00 110.65 ? 223 GLU B N   1 
ATOM   5546  C  CA  . GLU B 1 223 ? 169.685 199.507 121.956 1.00 110.65 ? 223 GLU B CA  1 
ATOM   5547  C  C   . GLU B 1 223 ? 169.322 200.067 123.326 1.00 110.65 ? 223 GLU B C   1 
ATOM   5548  O  O   . GLU B 1 223 ? 168.997 201.254 123.441 1.00 110.65 ? 223 GLU B O   1 
ATOM   5549  C  CB  . GLU B 1 223 ? 168.470 199.496 121.030 1.00 110.65 ? 223 GLU B CB  1 
ATOM   5550  C  CG  . GLU B 1 223 ? 167.300 198.669 121.525 1.00 110.65 ? 223 GLU B CG  1 
ATOM   5551  C  CD  . GLU B 1 223 ? 166.159 198.638 120.527 1.00 110.65 ? 223 GLU B CD  1 
ATOM   5552  O  OE1 . GLU B 1 223 ? 166.300 199.243 119.445 1.00 110.65 ? 223 GLU B OE1 1 
ATOM   5553  O  OE2 . GLU B 1 223 ? 165.121 198.013 120.822 1.00 110.65 ? 223 GLU B OE2 1 
ATOM   5554  N  N   . ALA B 1 224 ? 169.368 199.234 124.369 1.00 108.09 ? 224 ALA B N   1 
ATOM   5555  C  CA  . ALA B 1 224 ? 169.222 199.740 125.730 1.00 108.09 ? 224 ALA B CA  1 
ATOM   5556  C  C   . ALA B 1 224 ? 170.497 200.435 126.185 1.00 108.09 ? 224 ALA B C   1 
ATOM   5557  O  O   . ALA B 1 224 ? 170.456 201.546 126.728 1.00 108.09 ? 224 ALA B O   1 
ATOM   5558  C  CB  . ALA B 1 224 ? 168.866 198.599 126.683 1.00 108.09 ? 224 ALA B CB  1 
ATOM   5559  N  N   . ILE B 1 225 ? 171.645 199.787 125.978 1.00 110.33 ? 225 ILE B N   1 
ATOM   5560  C  CA  . ILE B 1 225 ? 172.918 200.414 126.313 1.00 110.33 ? 225 ILE B CA  1 
ATOM   5561  C  C   . ILE B 1 225 ? 173.156 201.630 125.429 1.00 110.33 ? 225 ILE B C   1 
ATOM   5562  O  O   . ILE B 1 225 ? 173.577 202.690 125.908 1.00 110.33 ? 225 ILE B O   1 
ATOM   5563  C  CB  . ILE B 1 225 ? 174.061 199.391 126.195 1.00 110.33 ? 225 ILE B CB  1 
ATOM   5564  C  CG1 . ILE B 1 225 ? 173.839 198.230 127.163 1.00 110.33 ? 225 ILE B CG1 1 
ATOM   5565  C  CG2 . ILE B 1 225 ? 175.395 200.051 126.471 1.00 110.33 ? 225 ILE B CG2 1 
ATOM   5566  C  CD1 . ILE B 1 225 ? 174.782 197.076 126.941 1.00 110.33 ? 225 ILE B CD1 1 
ATOM   5567  N  N   . GLU B 1 226 ? 172.883 201.503 124.127 1.00 115.77 ? 226 GLU B N   1 
ATOM   5568  C  CA  . GLU B 1 226 ? 173.017 202.651 123.236 1.00 115.77 ? 226 GLU B CA  1 
ATOM   5569  C  C   . GLU B 1 226 ? 172.038 203.755 123.613 1.00 115.77 ? 226 GLU B C   1 
ATOM   5570  O  O   . GLU B 1 226 ? 172.345 204.944 123.471 1.00 115.77 ? 226 GLU B O   1 
ATOM   5571  C  CB  . GLU B 1 226 ? 172.811 202.219 121.785 1.00 115.77 ? 226 GLU B CB  1 
ATOM   5572  C  CG  . GLU B 1 226 ? 172.952 203.348 120.773 1.00 115.77 ? 226 GLU B CG  1 
ATOM   5573  C  CD  . GLU B 1 226 ? 174.356 203.919 120.718 1.00 115.77 ? 226 GLU B CD  1 
ATOM   5574  O  OE1 . GLU B 1 226 ? 175.315 203.188 121.043 1.00 115.77 ? 226 GLU B OE1 1 
ATOM   5575  O  OE2 . GLU B 1 226 ? 174.501 205.104 120.349 1.00 115.77 ? 226 GLU B OE2 1 
ATOM   5576  N  N   . ALA B 1 227 ? 170.852 203.380 124.098 1.00 112.88 ? 227 ALA B N   1 
ATOM   5577  C  CA  . ALA B 1 227 ? 169.891 204.381 124.545 1.00 112.88 ? 227 ALA B CA  1 
ATOM   5578  C  C   . ALA B 1 227 ? 170.358 205.052 125.829 1.00 112.88 ? 227 ALA B C   1 
ATOM   5579  O  O   . ALA B 1 227 ? 169.980 206.194 126.117 1.00 112.88 ? 227 ALA B O   1 
ATOM   5580  C  CB  . ALA B 1 227 ? 168.517 203.740 124.740 1.00 112.88 ? 227 ALA B CB  1 
ATOM   5581  N  N   . TRP B 1 228 ? 171.180 204.356 126.616 1.00 111.94 ? 228 TRP B N   1 
ATOM   5582  C  CA  . TRP B 1 228 ? 171.734 204.960 127.821 1.00 111.94 ? 228 TRP B CA  1 
ATOM   5583  C  C   . TRP B 1 228 ? 172.868 205.918 127.486 1.00 111.94 ? 228 TRP B C   1 
ATOM   5584  O  O   . TRP B 1 228 ? 172.954 207.014 128.053 1.00 111.94 ? 228 TRP B O   1 
ATOM   5585  C  CB  . TRP B 1 228 ? 172.233 203.876 128.772 1.00 111.94 ? 228 TRP B CB  1 
ATOM   5586  C  CG  . TRP B 1 228 ? 172.798 204.422 130.044 1.00 111.94 ? 228 TRP B CG  1 
ATOM   5587  C  CD1 . TRP B 1 228 ? 172.105 204.987 131.070 1.00 111.94 ? 228 TRP B CD1 1 
ATOM   5588  C  CD2 . TRP B 1 228 ? 174.181 204.499 130.404 1.00 111.94 ? 228 TRP B CD2 1 
ATOM   5589  N  NE1 . TRP B 1 228 ? 172.966 205.385 132.062 1.00 111.94 ? 228 TRP B NE1 1 
ATOM   5590  C  CE2 . TRP B 1 228 ? 174.248 205.098 131.676 1.00 111.94 ? 228 TRP B CE2 1 
ATOM   5591  C  CE3 . TRP B 1 228 ? 175.368 204.107 129.780 1.00 111.94 ? 228 TRP B CE3 1 
ATOM   5592  C  CZ2 . TRP B 1 228 ? 175.453 205.317 132.335 1.00 111.94 ? 228 TRP B CZ2 1 
ATOM   5593  C  CZ3 . TRP B 1 228 ? 176.563 204.322 130.437 1.00 111.94 ? 228 TRP B CZ3 1 
ATOM   5594  C  CH2 . TRP B 1 228 ? 176.598 204.922 131.700 1.00 111.94 ? 228 TRP B CH2 1 
ATOM   5595  N  N   . ILE B 1 229 ? 173.755 205.518 126.571 1.00 117.97 ? 229 ILE B N   1 
ATOM   5596  C  CA  . ILE B 1 229 ? 174.930 206.331 126.263 1.00 117.97 ? 229 ILE B CA  1 
ATOM   5597  C  C   . ILE B 1 229 ? 174.514 207.661 125.652 1.00 117.97 ? 229 ILE B C   1 
ATOM   5598  O  O   . ILE B 1 229 ? 175.098 208.710 125.952 1.00 117.97 ? 229 ILE B O   1 
ATOM   5599  C  CB  . ILE B 1 229 ? 175.889 205.556 125.340 1.00 117.97 ? 229 ILE B CB  1 
ATOM   5600  C  CG1 . ILE B 1 229 ? 176.372 204.280 126.027 1.00 117.97 ? 229 ILE B CG1 1 
ATOM   5601  C  CG2 . ILE B 1 229 ? 177.079 206.420 124.955 1.00 117.97 ? 229 ILE B CG2 1 
ATOM   5602  C  CD1 . ILE B 1 229 ? 177.096 203.326 125.105 1.00 117.97 ? 229 ILE B CD1 1 
ATOM   5603  N  N   . ASN B 1 230 ? 173.491 207.645 124.797 1.00 120.69 ? 230 ASN B N   1 
ATOM   5604  C  CA  . ASN B 1 230 ? 173.017 208.875 124.177 1.00 120.69 ? 230 ASN B CA  1 
ATOM   5605  C  C   . ASN B 1 230 ? 172.251 209.767 125.145 1.00 120.69 ? 230 ASN B C   1 
ATOM   5606  O  O   . ASN B 1 230 ? 171.086 210.081 124.881 1.00 120.69 ? 230 ASN B O   1 
ATOM   5607  C  CB  . ASN B 1 230 ? 172.138 208.545 122.970 1.00 120.69 ? 230 ASN B CB  1 
ATOM   5608  C  CG  . ASN B 1 230 ? 172.930 207.958 121.821 1.00 120.69 ? 230 ASN B CG  1 
ATOM   5609  O  OD1 . ASN B 1 230 ? 174.037 208.405 121.523 1.00 120.69 ? 230 ASN B OD1 1 
ATOM   5610  N  ND2 . ASN B 1 230 ? 172.364 206.952 121.166 1.00 120.69 ? 230 ASN B ND2 1 
ATOM   5611  N  N   . PHE B 1 231 ? 172.869 210.178 126.251 1.00 118.12 ? 231 PHE B N   1 
ATOM   5612  C  CA  . PHE B 1 231 ? 172.224 211.069 127.205 1.00 118.12 ? 231 PHE B CA  1 
ATOM   5613  C  C   . PHE B 1 231 ? 173.138 212.254 127.488 1.00 118.12 ? 231 PHE B C   1 
ATOM   5614  O  O   . PHE B 1 231 ? 172.931 213.348 126.954 1.00 118.12 ? 231 PHE B O   1 
ATOM   5615  C  CB  . PHE B 1 231 ? 171.879 210.320 128.494 1.00 118.12 ? 231 PHE B CB  1 
ATOM   5616  C  CG  . PHE B 1 231 ? 171.113 211.143 129.489 1.00 118.12 ? 231 PHE B CG  1 
ATOM   5617  C  CD1 . PHE B 1 231 ? 169.765 211.397 129.304 1.00 118.12 ? 231 PHE B CD1 1 
ATOM   5618  C  CD2 . PHE B 1 231 ? 171.738 211.661 130.610 1.00 118.12 ? 231 PHE B CD2 1 
ATOM   5619  C  CE1 . PHE B 1 231 ? 169.057 212.152 130.218 1.00 118.12 ? 231 PHE B CE1 1 
ATOM   5620  C  CE2 . PHE B 1 231 ? 171.034 212.417 131.527 1.00 118.12 ? 231 PHE B CE2 1 
ATOM   5621  C  CZ  . PHE B 1 231 ? 169.693 212.662 131.330 1.00 118.12 ? 231 PHE B CZ  1 
ATOM   5622  N  N   . ASN B 1 232 ? 174.157 212.043 128.325 1.00 124.71 ? 232 ASN B N   1 
ATOM   5623  C  CA  . ASN B 1 232 ? 175.220 213.024 128.554 1.00 124.71 ? 232 ASN B CA  1 
ATOM   5624  C  C   . ASN B 1 232 ? 176.471 212.503 127.845 1.00 124.71 ? 232 ASN B C   1 
ATOM   5625  O  O   . ASN B 1 232 ? 177.526 212.315 128.455 1.00 124.71 ? 232 ASN B O   1 
ATOM   5626  C  CB  . ASN B 1 232 ? 175.445 213.276 130.057 1.00 124.71 ? 232 ASN B CB  1 
ATOM   5627  C  CG  . ASN B 1 232 ? 175.789 212.013 130.828 1.00 124.71 ? 232 ASN B CG  1 
ATOM   5628  O  OD1 . ASN B 1 232 ? 175.978 210.944 130.250 1.00 124.71 ? 232 ASN B OD1 1 
ATOM   5629  N  ND2 . ASN B 1 232 ? 175.868 212.135 132.149 1.00 124.71 ? 232 ASN B ND2 1 
ATOM   5630  N  N   . LYS B 1 233 ? 176.342 212.290 126.531 1.00 126.22 ? 233 LYS B N   1 
ATOM   5631  C  CA  . LYS B 1 233 ? 177.431 211.709 125.751 1.00 126.22 ? 233 LYS B CA  1 
ATOM   5632  C  C   . LYS B 1 233 ? 178.654 212.617 125.728 1.00 126.22 ? 233 LYS B C   1 
ATOM   5633  O  O   . LYS B 1 233 ? 179.731 212.210 125.276 1.00 126.22 ? 233 LYS B O   1 
ATOM   5634  C  CB  . LYS B 1 233 ? 176.952 211.418 124.329 1.00 126.22 ? 233 LYS B CB  1 
ATOM   5635  C  CG  . LYS B 1 233 ? 176.582 212.661 123.538 1.00 126.22 ? 233 LYS B CG  1 
ATOM   5636  C  CD  . LYS B 1 233 ? 176.137 212.308 122.131 1.00 126.22 ? 233 LYS B CD  1 
ATOM   5637  C  CE  . LYS B 1 233 ? 174.766 211.653 122.137 1.00 126.22 ? 233 LYS B CE  1 
ATOM   5638  N  NZ  . LYS B 1 233 ? 173.705 212.594 122.586 1.00 126.22 ? 233 LYS B NZ  1 
ATOM   5639  N  N   . GLU B 1 234 ? 178.506 213.856 126.202 1.00 129.27 ? 234 GLU B N   1 
ATOM   5640  C  CA  . GLU B 1 234 ? 179.661 214.735 126.348 1.00 129.27 ? 234 GLU B CA  1 
ATOM   5641  C  C   . GLU B 1 234 ? 180.664 214.172 127.346 1.00 129.27 ? 234 GLU B C   1 
ATOM   5642  O  O   . GLU B 1 234 ? 181.854 214.499 127.284 1.00 129.27 ? 234 GLU B O   1 
ATOM   5643  C  CB  . GLU B 1 234 ? 179.200 216.126 126.782 1.00 129.27 ? 234 GLU B CB  1 
ATOM   5644  C  CG  . GLU B 1 234 ? 178.344 216.845 125.752 1.00 129.27 ? 234 GLU B CG  1 
ATOM   5645  C  CD  . GLU B 1 234 ? 177.855 218.194 126.241 1.00 129.27 ? 234 GLU B CD  1 
ATOM   5646  O  OE1 . GLU B 1 234 ? 178.081 218.516 127.426 1.00 129.27 ? 234 GLU B OE1 1 
ATOM   5647  O  OE2 . GLU B 1 234 ? 177.241 218.931 125.441 1.00 129.27 ? 234 GLU B OE2 1 
ATOM   5648  N  N   . GLU B 1 235 ? 180.205 213.321 128.265 1.00 128.23 ? 235 GLU B N   1 
ATOM   5649  C  CA  . GLU B 1 235 ? 181.058 212.714 129.275 1.00 128.23 ? 235 GLU B CA  1 
ATOM   5650  C  C   . GLU B 1 235 ? 180.850 211.212 129.408 1.00 128.23 ? 235 GLU B C   1 
ATOM   5651  O  O   . GLU B 1 235 ? 181.409 210.605 130.330 1.00 128.23 ? 235 GLU B O   1 
ATOM   5652  C  CB  . GLU B 1 235 ? 180.819 213.379 130.637 1.00 128.23 ? 235 GLU B CB  1 
ATOM   5653  C  CG  . GLU B 1 235 ? 179.420 213.153 131.190 1.00 128.23 ? 235 GLU B CG  1 
ATOM   5654  C  CD  . GLU B 1 235 ? 179.181 213.879 132.499 1.00 128.23 ? 235 GLU B CD  1 
ATOM   5655  O  OE1 . GLU B 1 235 ? 180.099 214.584 132.967 1.00 128.23 ? 235 GLU B OE1 1 
ATOM   5656  O  OE2 . GLU B 1 235 ? 178.073 213.744 133.061 1.00 128.23 ? 235 GLU B OE2 1 
ATOM   5657  N  N   . ARG B 1 236 ? 180.073 210.595 128.519 1.00 121.01 ? 236 ARG B N   1 
ATOM   5658  C  CA  . ARG B 1 236 ? 179.720 209.189 128.637 1.00 121.01 ? 236 ARG B CA  1 
ATOM   5659  C  C   . ARG B 1 236 ? 180.193 208.351 127.454 1.00 121.01 ? 236 ARG B C   1 
ATOM   5660  O  O   . ARG B 1 236 ? 180.285 207.124 127.582 1.00 121.01 ? 236 ARG B O   1 
ATOM   5661  C  CB  . ARG B 1 236 ? 178.199 209.051 128.817 1.00 121.01 ? 236 ARG B CB  1 
ATOM   5662  C  CG  . ARG B 1 236 ? 177.697 207.645 129.102 1.00 121.01 ? 236 ARG B CG  1 
ATOM   5663  C  CD  . ARG B 1 236 ? 176.206 207.634 129.422 1.00 121.01 ? 236 ARG B CD  1 
ATOM   5664  N  NE  . ARG B 1 236 ? 175.911 208.232 130.722 1.00 121.01 ? 236 ARG B NE  1 
ATOM   5665  C  CZ  . ARG B 1 236 ? 174.683 208.457 131.181 1.00 121.01 ? 236 ARG B CZ  1 
ATOM   5666  N  NH1 . ARG B 1 236 ? 173.628 208.135 130.447 1.00 121.01 ? 236 ARG B NH1 1 
ATOM   5667  N  NH2 . ARG B 1 236 ? 174.511 209.006 132.375 1.00 121.01 ? 236 ARG B NH2 1 
ATOM   5668  N  N   . GLU B 1 237 ? 180.512 208.974 126.316 1.00 126.41 ? 237 GLU B N   1 
ATOM   5669  C  CA  . GLU B 1 237 ? 181.031 208.220 125.177 1.00 126.41 ? 237 GLU B CA  1 
ATOM   5670  C  C   . GLU B 1 237 ? 182.348 207.536 125.523 1.00 126.41 ? 237 GLU B C   1 
ATOM   5671  O  O   . GLU B 1 237 ? 182.477 206.313 125.393 1.00 126.41 ? 237 GLU B O   1 
ATOM   5672  C  CB  . GLU B 1 237 ? 181.208 209.140 123.969 1.00 126.41 ? 237 GLU B CB  1 
ATOM   5673  C  CG  . GLU B 1 237 ? 179.910 209.614 123.341 1.00 126.41 ? 237 GLU B CG  1 
ATOM   5674  C  CD  . GLU B 1 237 ? 179.141 208.489 122.673 1.00 126.41 ? 237 GLU B CD  1 
ATOM   5675  O  OE1 . GLU B 1 237 ? 179.782 207.535 122.183 1.00 126.41 ? 237 GLU B OE1 1 
ATOM   5676  O  OE2 . GLU B 1 237 ? 177.895 208.564 122.630 1.00 126.41 ? 237 GLU B OE2 1 
ATOM   5677  N  N   . ALA B 1 238 ? 183.340 208.310 125.971 1.00 125.63 ? 238 ALA B N   1 
ATOM   5678  C  CA  . ALA B 1 238 ? 184.614 207.718 126.366 1.00 125.63 ? 238 ALA B CA  1 
ATOM   5679  C  C   . ALA B 1 238 ? 184.535 207.089 127.750 1.00 125.63 ? 238 ALA B C   1 
ATOM   5680  O  O   . ALA B 1 238 ? 185.507 207.141 128.512 1.00 125.63 ? 238 ALA B O   1 
ATOM   5681  C  CB  . ALA B 1 238 ? 185.720 208.772 126.325 1.00 125.63 ? 238 ALA B CB  1 
ATOM   5682  N  N   . PHE B 1 239 ? 183.395 206.485 128.087 1.00 120.99 ? 239 PHE B N   1 
ATOM   5683  C  CA  . PHE B 1 239 ? 183.175 205.939 129.418 1.00 120.99 ? 239 PHE B CA  1 
ATOM   5684  C  C   . PHE B 1 239 ? 182.268 204.716 129.393 1.00 120.99 ? 239 PHE B C   1 
ATOM   5685  O  O   . PHE B 1 239 ? 182.142 204.029 130.413 1.00 120.99 ? 239 PHE B O   1 
ATOM   5686  C  CB  . PHE B 1 239 ? 182.588 207.031 130.322 1.00 120.99 ? 239 PHE B CB  1 
ATOM   5687  C  CG  . PHE B 1 239 ? 182.378 206.606 131.747 1.00 120.99 ? 239 PHE B CG  1 
ATOM   5688  C  CD1 . PHE B 1 239 ? 183.454 206.446 132.604 1.00 120.99 ? 239 PHE B CD1 1 
ATOM   5689  C  CD2 . PHE B 1 239 ? 181.101 206.393 132.238 1.00 120.99 ? 239 PHE B CD2 1 
ATOM   5690  C  CE1 . PHE B 1 239 ? 183.262 206.063 133.918 1.00 120.99 ? 239 PHE B CE1 1 
ATOM   5691  C  CE2 . PHE B 1 239 ? 180.902 206.012 133.549 1.00 120.99 ? 239 PHE B CE2 1 
ATOM   5692  C  CZ  . PHE B 1 239 ? 181.984 205.847 134.391 1.00 120.99 ? 239 PHE B CZ  1 
ATOM   5693  N  N   . ALA B 1 240 ? 181.655 204.417 128.250 1.00 122.96 ? 240 ALA B N   1 
ATOM   5694  C  CA  . ALA B 1 240 ? 180.714 203.315 128.135 1.00 122.96 ? 240 ALA B CA  1 
ATOM   5695  C  C   . ALA B 1 240 ? 180.953 202.437 126.913 1.00 122.96 ? 240 ALA B C   1 
ATOM   5696  O  O   . ALA B 1 240 ? 180.053 202.302 126.080 1.00 122.96 ? 240 ALA B O   1 
ATOM   5697  C  CB  . ALA B 1 240 ? 179.281 203.851 128.109 1.00 122.96 ? 240 ALA B CB  1 
ATOM   5698  N  N   . GLU B 1 241 ? 182.142 201.846 126.781 1.00 121.02 ? 241 GLU B N   1 
ATOM   5699  C  CA  . GLU B 1 241 ? 182.346 200.823 125.761 1.00 121.02 ? 241 GLU B CA  1 
ATOM   5700  C  C   . GLU B 1 241 ? 182.675 199.486 126.411 1.00 121.02 ? 241 GLU B C   1 
ATOM   5701  O  O   . GLU B 1 241 ? 182.363 198.418 125.865 1.00 121.02 ? 241 GLU B O   1 
ATOM   5702  C  CB  . GLU B 1 241 ? 183.450 201.254 124.796 1.00 121.02 ? 241 GLU B CB  1 
ATOM   5703  C  CG  . GLU B 1 241 ? 183.495 200.470 123.490 1.00 121.02 ? 241 GLU B CG  1 
ATOM   5704  C  CD  . GLU B 1 241 ? 184.274 199.176 123.599 1.00 121.02 ? 241 GLU B CD  1 
ATOM   5705  O  OE1 . GLU B 1 241 ? 185.198 199.104 124.437 1.00 121.02 ? 241 GLU B OE1 1 
ATOM   5706  O  OE2 . GLU B 1 241 ? 183.965 198.233 122.842 1.00 121.02 ? 241 GLU B OE2 1 
ATOM   5707  N  N   . SER B 1 242 ? 183.296 199.530 127.595 1.00 117.92 ? 242 SER B N   1 
ATOM   5708  C  CA  . SER B 1 242 ? 183.468 198.322 128.391 1.00 117.92 ? 242 SER B CA  1 
ATOM   5709  C  C   . SER B 1 242 ? 182.126 197.687 128.727 1.00 117.92 ? 242 SER B C   1 
ATOM   5710  O  O   . SER B 1 242 ? 182.056 196.481 128.990 1.00 117.92 ? 242 SER B O   1 
ATOM   5711  C  CB  . SER B 1 242 ? 184.244 198.638 129.670 1.00 117.92 ? 242 SER B CB  1 
ATOM   5712  O  OG  . SER B 1 242 ? 185.562 199.066 129.373 1.00 117.92 ? 242 SER B OG  1 
ATOM   5713  N  N   . LEU B 1 243 ? 181.053 198.483 128.728 1.00 114.57 ? 243 LEU B N   1 
ATOM   5714  C  CA  . LEU B 1 243 ? 179.715 197.922 128.861 1.00 114.57 ? 243 LEU B CA  1 
ATOM   5715  C  C   . LEU B 1 243 ? 179.395 196.995 127.698 1.00 114.57 ? 243 LEU B C   1 
ATOM   5716  O  O   . LEU B 1 243 ? 178.932 195.866 127.901 1.00 114.57 ? 243 LEU B O   1 
ATOM   5717  C  CB  . LEU B 1 243 ? 178.683 199.044 128.943 1.00 114.57 ? 243 LEU B CB  1 
ATOM   5718  C  CG  . LEU B 1 243 ? 178.762 199.929 130.182 1.00 114.57 ? 243 LEU B CG  1 
ATOM   5719  C  CD1 . LEU B 1 243 ? 177.797 201.087 130.058 1.00 114.57 ? 243 LEU B CD1 1 
ATOM   5720  C  CD2 . LEU B 1 243 ? 178.463 199.111 131.421 1.00 114.57 ? 243 LEU B CD2 1 
ATOM   5721  N  N   . ARG B 1 244 ? 179.641 197.453 126.468 1.00 116.18 ? 244 ARG B N   1 
ATOM   5722  C  CA  . ARG B 1 244 ? 179.345 196.625 125.305 1.00 116.18 ? 244 ARG B CA  1 
ATOM   5723  C  C   . ARG B 1 244 ? 180.311 195.452 125.206 1.00 116.18 ? 244 ARG B C   1 
ATOM   5724  O  O   . ARG B 1 244 ? 179.981 194.414 124.621 1.00 116.18 ? 244 ARG B O   1 
ATOM   5725  C  CB  . ARG B 1 244 ? 179.375 197.476 124.034 1.00 116.18 ? 244 ARG B CB  1 
ATOM   5726  C  CG  . ARG B 1 244 ? 178.958 196.733 122.776 1.00 116.18 ? 244 ARG B CG  1 
ATOM   5727  C  CD  . ARG B 1 244 ? 178.837 197.675 121.592 1.00 116.18 ? 244 ARG B CD  1 
ATOM   5728  N  NE  . ARG B 1 244 ? 177.708 198.588 121.747 1.00 116.18 ? 244 ARG B NE  1 
ATOM   5729  C  CZ  . ARG B 1 244 ? 177.456 199.614 120.940 1.00 116.18 ? 244 ARG B CZ  1 
ATOM   5730  N  NH1 . ARG B 1 244 ? 178.254 199.862 119.910 1.00 116.18 ? 244 ARG B NH1 1 
ATOM   5731  N  NH2 . ARG B 1 244 ? 176.405 200.391 121.161 1.00 116.18 ? 244 ARG B NH2 1 
ATOM   5732  N  N   . THR B 1 245 ? 181.508 195.587 125.784 1.00 115.14 ? 245 THR B N   1 
ATOM   5733  C  CA  . THR B 1 245 ? 182.391 194.430 125.870 1.00 115.14 ? 245 THR B CA  1 
ATOM   5734  C  C   . THR B 1 245 ? 182.008 193.492 127.007 1.00 115.14 ? 245 THR B C   1 
ATOM   5735  O  O   . THR B 1 245 ? 182.654 192.453 127.180 1.00 115.14 ? 245 THR B O   1 
ATOM   5736  C  CB  . THR B 1 245 ? 183.848 194.860 126.052 1.00 115.14 ? 245 THR B CB  1 
ATOM   5737  O  OG1 . THR B 1 245 ? 184.005 195.498 127.324 1.00 115.14 ? 245 THR B OG1 1 
ATOM   5738  C  CG2 . THR B 1 245 ? 184.261 195.825 124.955 1.00 115.14 ? 245 THR B CG2 1 
ATOM   5739  N  N   . SER B 1 246 ? 180.982 193.836 127.785 1.00 110.35 ? 246 SER B N   1 
ATOM   5740  C  CA  . SER B 1 246 ? 180.530 193.021 128.904 1.00 110.35 ? 246 SER B CA  1 
ATOM   5741  C  C   . SER B 1 246 ? 179.092 192.545 128.743 1.00 110.35 ? 246 SER B C   1 
ATOM   5742  O  O   . SER B 1 246 ? 178.592 191.815 129.603 1.00 110.35 ? 246 SER B O   1 
ATOM   5743  C  CB  . SER B 1 246 ? 180.679 193.797 130.214 1.00 110.35 ? 246 SER B CB  1 
ATOM   5744  O  OG  . SER B 1 246 ? 179.821 194.924 130.237 1.00 110.35 ? 246 SER B OG  1 
ATOM   5745  N  N   . LEU B 1 247 ? 178.417 192.945 127.667 1.00 107.81 ? 247 LEU B N   1 
ATOM   5746  C  CA  . LEU B 1 247 ? 177.055 192.499 127.408 1.00 107.81 ? 247 LEU B CA  1 
ATOM   5747  C  C   . LEU B 1 247 ? 177.034 191.000 127.139 1.00 107.81 ? 247 LEU B C   1 
ATOM   5748  O  O   . LEU B 1 247 ? 177.968 190.453 126.546 1.00 107.81 ? 247 LEU B O   1 
ATOM   5749  C  CB  . LEU B 1 247 ? 176.467 193.264 126.223 1.00 107.81 ? 247 LEU B CB  1 
ATOM   5750  C  CG  . LEU B 1 247 ? 175.046 192.914 125.779 1.00 107.81 ? 247 LEU B CG  1 
ATOM   5751  C  CD1 . LEU B 1 247 ? 174.049 193.150 126.893 1.00 107.81 ? 247 LEU B CD1 1 
ATOM   5752  C  CD2 . LEU B 1 247 ? 174.671 193.721 124.548 1.00 107.81 ? 247 LEU B CD2 1 
ATOM   5753  N  N   . LYS B 1 248 ? 175.968 190.337 127.578 1.00 107.41 ? 248 LYS B N   1 
ATOM   5754  C  CA  . LYS B 1 248 ? 175.823 188.901 127.414 1.00 107.41 ? 248 LYS B CA  1 
ATOM   5755  C  C   . LYS B 1 248 ? 174.482 188.567 126.762 1.00 107.41 ? 248 LYS B C   1 
ATOM   5756  O  O   . LYS B 1 248 ? 173.763 189.435 126.261 1.00 107.41 ? 248 LYS B O   1 
ATOM   5757  C  CB  . LYS B 1 248 ? 175.961 188.193 128.762 1.00 107.41 ? 248 LYS B CB  1 
ATOM   5758  C  CG  . LYS B 1 248 ? 177.371 188.185 129.322 1.00 107.41 ? 248 LYS B CG  1 
ATOM   5759  C  CD  . LYS B 1 248 ? 177.410 187.559 130.707 1.00 107.41 ? 248 LYS B CD  1 
ATOM   5760  C  CE  . LYS B 1 248 ? 177.675 186.061 130.640 1.00 107.41 ? 248 LYS B CE  1 
ATOM   5761  N  NZ  . LYS B 1 248 ? 176.514 185.291 130.109 1.00 107.41 ? 248 LYS B NZ  1 
ATOM   5762  N  N   . GLU B 1 249 ? 174.150 187.278 126.773 1.00 106.76 ? 249 GLU B N   1 
ATOM   5763  C  CA  . GLU B 1 249 ? 172.893 186.782 126.233 1.00 106.76 ? 249 GLU B CA  1 
ATOM   5764  C  C   . GLU B 1 249 ? 172.660 185.372 126.755 1.00 106.76 ? 249 GLU B C   1 
ATOM   5765  O  O   . GLU B 1 249 ? 173.602 184.583 126.866 1.00 106.76 ? 249 GLU B O   1 
ATOM   5766  C  CB  . GLU B 1 249 ? 172.892 186.793 124.700 1.00 106.76 ? 249 GLU B CB  1 
ATOM   5767  C  CG  . GLU B 1 249 ? 171.627 186.220 124.080 1.00 106.76 ? 249 GLU B CG  1 
ATOM   5768  C  CD  . GLU B 1 249 ? 170.388 187.026 124.416 1.00 106.76 ? 249 GLU B CD  1 
ATOM   5769  O  OE1 . GLU B 1 249 ? 170.505 188.254 124.614 1.00 106.76 ? 249 GLU B OE1 1 
ATOM   5770  O  OE2 . GLU B 1 249 ? 169.298 186.423 124.502 1.00 106.76 ? 249 GLU B OE2 1 
ATOM   5771  N  N   . ILE B 1 250 ? 171.405 185.064 127.072 1.00 107.68 ? 250 ILE B N   1 
ATOM   5772  C  CA  . ILE B 1 250 ? 171.023 183.770 127.618 1.00 107.68 ? 250 ILE B CA  1 
ATOM   5773  C  C   . ILE B 1 250 ? 169.840 183.246 126.816 1.00 107.68 ? 250 ILE B C   1 
ATOM   5774  O  O   . ILE B 1 250 ? 169.196 183.991 126.070 1.00 107.68 ? 250 ILE B O   1 
ATOM   5775  C  CB  . ILE B 1 250 ? 170.681 183.873 129.124 1.00 107.68 ? 250 ILE B CB  1 
ATOM   5776  C  CG1 . ILE B 1 250 ? 170.662 182.493 129.788 1.00 107.68 ? 250 ILE B CG1 1 
ATOM   5777  C  CG2 . ILE B 1 250 ? 169.351 184.585 129.320 1.00 107.68 ? 250 ILE B CG2 1 
ATOM   5778  C  CD1 . ILE B 1 250 ? 170.663 182.541 131.298 1.00 107.68 ? 250 ILE B CD1 1 
ATOM   5779  N  N   . GLY B 1 251 ? 169.559 181.944 126.962 1.00 108.71 ? 251 GLY B N   1 
ATOM   5780  C  CA  . GLY B 1 251 ? 168.455 181.324 126.261 1.00 108.71 ? 251 GLY B CA  1 
ATOM   5781  C  C   . GLY B 1 251 ? 167.093 181.749 126.791 1.00 108.71 ? 251 GLY B C   1 
ATOM   5782  O  O   . GLY B 1 251 ? 166.875 182.889 127.196 1.00 108.71 ? 251 GLY B O   1 
ATOM   5783  N  N   . GLU B 1 252 ? 166.163 180.798 126.782 1.00 104.35 ? 252 GLU B N   1 
ATOM   5784  C  CA  . GLU B 1 252 ? 164.798 181.075 127.210 1.00 104.35 ? 252 GLU B CA  1 
ATOM   5785  C  C   . GLU B 1 252 ? 164.342 180.057 128.247 1.00 104.35 ? 252 GLU B C   1 
ATOM   5786  O  O   . GLU B 1 252 ? 164.122 178.884 127.928 1.00 104.35 ? 252 GLU B O   1 
ATOM   5787  C  CB  . GLU B 1 252 ? 163.850 181.066 126.011 1.00 104.35 ? 252 GLU B CB  1 
ATOM   5788  C  CG  . GLU B 1 252 ? 164.068 182.213 125.039 1.00 104.35 ? 252 GLU B CG  1 
ATOM   5789  C  CD  . GLU B 1 252 ? 165.167 181.929 124.036 1.00 104.35 ? 252 GLU B CD  1 
ATOM   5790  O  OE1 . GLU B 1 252 ? 165.705 180.802 124.044 1.00 104.35 ? 252 GLU B OE1 1 
ATOM   5791  O  OE2 . GLU B 1 252 ? 165.496 182.834 123.243 1.00 104.35 ? 252 GLU B OE2 1 
ATOM   5792  N  N   . ASN B 1 253 ? 164.196 180.514 129.494 1.00 99.87  ? 253 ASN B N   1 
ATOM   5793  C  CA  . ASN B 1 253 ? 163.667 179.683 130.568 1.00 99.87  ? 253 ASN B CA  1 
ATOM   5794  C  C   . ASN B 1 253 ? 162.366 180.255 131.120 1.00 99.87  ? 253 ASN B C   1 
ATOM   5795  O  O   . ASN B 1 253 ? 162.252 180.503 132.326 1.00 99.87  ? 253 ASN B O   1 
ATOM   5796  C  CB  . ASN B 1 253 ? 164.689 179.514 131.693 1.00 99.87  ? 253 ASN B CB  1 
ATOM   5797  C  CG  . ASN B 1 253 ? 165.906 178.725 131.256 1.00 99.87  ? 253 ASN B CG  1 
ATOM   5798  O  OD1 . ASN B 1 253 ? 167.018 179.248 131.207 1.00 99.87  ? 253 ASN B OD1 1 
ATOM   5799  N  ND2 . ASN B 1 253 ? 165.698 177.455 130.933 1.00 99.87  ? 253 ASN B ND2 1 
ATOM   5800  N  N   . VAL B 1 254 ? 161.381 180.473 130.253 1.00 95.51  ? 254 VAL B N   1 
ATOM   5801  C  CA  . VAL B 1 254 ? 160.062 180.958 130.640 1.00 95.51  ? 254 VAL B CA  1 
ATOM   5802  C  C   . VAL B 1 254 ? 159.070 179.917 130.135 1.00 95.51  ? 254 VAL B C   1 
ATOM   5803  O  O   . VAL B 1 254 ? 158.294 180.181 129.207 1.00 95.51  ? 254 VAL B O   1 
ATOM   5804  C  CB  . VAL B 1 254 ? 159.771 182.351 130.060 1.00 95.51  ? 254 VAL B CB  1 
ATOM   5805  C  CG1 . VAL B 1 254 ? 158.445 182.892 130.571 1.00 95.51  ? 254 VAL B CG1 1 
ATOM   5806  C  CG2 . VAL B 1 254 ? 160.903 183.311 130.386 1.00 95.51  ? 254 VAL B CG2 1 
ATOM   5807  N  N   . HIS B 1 255 ? 159.110 178.726 130.730 1.00 83.06  ? 255 HIS B N   1 
ATOM   5808  C  CA  . HIS B 1 255 ? 158.416 177.564 130.195 1.00 83.06  ? 255 HIS B CA  1 
ATOM   5809  C  C   . HIS B 1 255 ? 157.352 177.098 131.176 1.00 83.06  ? 255 HIS B C   1 
ATOM   5810  O  O   . HIS B 1 255 ? 157.257 177.584 132.305 1.00 83.06  ? 255 HIS B O   1 
ATOM   5811  C  CB  . HIS B 1 255 ? 159.391 176.417 129.907 1.00 83.06  ? 255 HIS B CB  1 
ATOM   5812  C  CG  . HIS B 1 255 ? 160.421 176.738 128.872 1.00 83.06  ? 255 HIS B CG  1 
ATOM   5813  N  ND1 . HIS B 1 255 ? 160.149 176.729 127.521 1.00 83.06  ? 255 HIS B ND1 1 
ATOM   5814  C  CD2 . HIS B 1 255 ? 161.724 177.085 128.991 1.00 83.06  ? 255 HIS B CD2 1 
ATOM   5815  C  CE1 . HIS B 1 255 ? 161.241 177.051 126.853 1.00 83.06  ? 255 HIS B CE1 1 
ATOM   5816  N  NE2 . HIS B 1 255 ? 162.211 177.273 127.721 1.00 83.06  ? 255 HIS B NE2 1 
ATOM   5817  N  N   . ILE B 1 256 ? 156.549 176.134 130.727 1.00 76.86  ? 256 ILE B N   1 
ATOM   5818  C  CA  . ILE B 1 256 ? 155.551 175.488 131.571 1.00 76.86  ? 256 ILE B CA  1 
ATOM   5819  C  C   . ILE B 1 256 ? 155.657 173.977 131.408 1.00 76.86  ? 256 ILE B C   1 
ATOM   5820  O  O   . ILE B 1 256 ? 155.595 173.234 132.394 1.00 76.86  ? 256 ILE B O   1 
ATOM   5821  C  CB  . ILE B 1 256 ? 154.127 175.975 131.243 1.00 76.86  ? 256 ILE B CB  1 
ATOM   5822  C  CG1 . ILE B 1 256 ? 153.982 177.471 131.515 1.00 76.86  ? 256 ILE B CG1 1 
ATOM   5823  C  CG2 . ILE B 1 256 ? 153.106 175.209 132.062 1.00 76.86  ? 256 ILE B CG2 1 
ATOM   5824  C  CD1 . ILE B 1 256 ? 154.135 177.838 132.968 1.00 76.86  ? 256 ILE B CD1 1 
ATOM   5825  N  N   . TYR B 1 257 ? 155.822 173.517 130.164 1.00 72.62  ? 257 TYR B N   1 
ATOM   5826  C  CA  . TYR B 1 257 ? 155.860 172.091 129.848 1.00 72.62  ? 257 TYR B CA  1 
ATOM   5827  C  C   . TYR B 1 257 ? 154.594 171.368 130.290 1.00 72.62  ? 257 TYR B C   1 
ATOM   5828  O  O   . TYR B 1 257 ? 154.569 170.754 131.359 1.00 72.62  ? 257 TYR B O   1 
ATOM   5829  C  CB  . TYR B 1 257 ? 157.080 171.416 130.483 1.00 72.62  ? 257 TYR B CB  1 
ATOM   5830  C  CG  . TYR B 1 257 ? 158.381 171.632 129.749 1.00 72.62  ? 257 TYR B CG  1 
ATOM   5831  C  CD1 . TYR B 1 257 ? 158.397 172.044 128.426 1.00 72.62  ? 257 TYR B CD1 1 
ATOM   5832  C  CD2 . TYR B 1 257 ? 159.595 171.422 130.382 1.00 72.62  ? 257 TYR B CD2 1 
ATOM   5833  C  CE1 . TYR B 1 257 ? 159.587 172.235 127.755 1.00 72.62  ? 257 TYR B CE1 1 
ATOM   5834  C  CE2 . TYR B 1 257 ? 160.786 171.609 129.720 1.00 72.62  ? 257 TYR B CE2 1 
ATOM   5835  C  CZ  . TYR B 1 257 ? 160.778 172.020 128.410 1.00 72.62  ? 257 TYR B CZ  1 
ATOM   5836  O  OH  . TYR B 1 257 ? 161.968 172.210 127.749 1.00 72.62  ? 257 TYR B OH  1 
ATOM   5837  N  N   . LEU B 1 258 ? 153.546 171.421 129.474 1.00 72.59  ? 258 LEU B N   1 
ATOM   5838  C  CA  . LEU B 1 258 ? 152.316 170.690 129.736 1.00 72.59  ? 258 LEU B CA  1 
ATOM   5839  C  C   . LEU B 1 258 ? 152.448 169.278 129.189 1.00 72.59  ? 258 LEU B C   1 
ATOM   5840  O  O   . LEU B 1 258 ? 152.848 169.086 128.037 1.00 72.59  ? 258 LEU B O   1 
ATOM   5841  C  CB  . LEU B 1 258 ? 151.105 171.373 129.100 1.00 72.59  ? 258 LEU B CB  1 
ATOM   5842  C  CG  . LEU B 1 258 ? 150.720 172.777 129.564 1.00 72.59  ? 258 LEU B CG  1 
ATOM   5843  C  CD1 . LEU B 1 258 ? 149.512 173.269 128.784 1.00 72.59  ? 258 LEU B CD1 1 
ATOM   5844  C  CD2 . LEU B 1 258 ? 150.453 172.818 131.049 1.00 72.59  ? 258 LEU B CD2 1 
ATOM   5845  N  N   . ILE B 1 259 ? 152.114 168.289 130.015 1.00 71.34  ? 259 ILE B N   1 
ATOM   5846  C  CA  . ILE B 1 259 ? 152.161 166.895 129.591 1.00 71.34  ? 259 ILE B CA  1 
ATOM   5847  C  C   . ILE B 1 259 ? 150.793 166.266 129.807 1.00 71.34  ? 259 ILE B C   1 
ATOM   5848  O  O   . ILE B 1 259 ? 150.431 165.910 130.934 1.00 71.34  ? 259 ILE B O   1 
ATOM   5849  C  CB  . ILE B 1 259 ? 153.253 166.114 130.342 1.00 71.34  ? 259 ILE B CB  1 
ATOM   5850  C  CG1 . ILE B 1 259 ? 154.635 166.684 130.024 1.00 71.34  ? 259 ILE B CG1 1 
ATOM   5851  C  CG2 . ILE B 1 259 ? 153.198 164.645 129.979 1.00 71.34  ? 259 ILE B CG2 1 
ATOM   5852  C  CD1 . ILE B 1 259 ? 155.733 166.144 130.907 1.00 71.34  ? 259 ILE B CD1 1 
ATOM   5853  N  N   . GLY B 1 260 ? 150.023 166.130 128.734 1.00 87.93  ? 260 GLY B N   1 
ATOM   5854  C  CA  . GLY B 1 260 ? 148.705 165.548 128.849 1.00 87.93  ? 260 GLY B CA  1 
ATOM   5855  C  C   . GLY B 1 260 ? 148.329 164.723 127.636 1.00 87.93  ? 260 GLY B C   1 
ATOM   5856  O  O   . GLY B 1 260 ? 148.839 164.907 126.531 1.00 87.93  ? 260 GLY B O   1 
ATOM   5857  N  N   . LYS B 1 261 ? 147.409 163.792 127.856 1.00 101.84 ? 261 LYS B N   1 
ATOM   5858  C  CA  . LYS B 1 261 ? 146.963 162.871 126.823 1.00 101.84 ? 261 LYS B CA  1 
ATOM   5859  C  C   . LYS B 1 261 ? 145.869 163.509 125.977 1.00 101.84 ? 261 LYS B C   1 
ATOM   5860  O  O   . LYS B 1 261 ? 144.790 163.843 126.472 1.00 101.84 ? 261 LYS B O   1 
ATOM   5861  C  CB  . LYS B 1 261 ? 146.454 161.569 127.441 1.00 101.84 ? 261 LYS B CB  1 
ATOM   5862  C  CG  . LYS B 1 261 ? 146.142 160.482 126.431 1.00 101.84 ? 261 LYS B CG  1 
ATOM   5863  C  CD  . LYS B 1 261 ? 145.674 159.214 127.124 1.00 101.84 ? 261 LYS B CD  1 
ATOM   5864  C  CE  . LYS B 1 261 ? 146.813 158.558 127.886 1.00 101.84 ? 261 LYS B CE  1 
ATOM   5865  N  NZ  . LYS B 1 261 ? 147.876 158.049 126.977 1.00 101.84 ? 261 LYS B NZ  1 
ATOM   5866  N  N   . GLU B 1 262 ? 146.162 163.672 124.686 1.00 113.39 ? 262 GLU B N   1 
ATOM   5867  C  CA  . GLU B 1 262 ? 145.249 164.287 123.731 1.00 113.39 ? 262 GLU B CA  1 
ATOM   5868  C  C   . GLU B 1 262 ? 143.976 163.467 123.539 1.00 113.39 ? 262 GLU B C   1 
ATOM   5869  O  O   . GLU B 1 262 ? 143.994 162.243 123.713 1.00 113.39 ? 262 GLU B O   1 
ATOM   5870  C  CB  . GLU B 1 262 ? 145.962 164.499 122.394 1.00 113.39 ? 262 GLU B CB  1 
ATOM   5871  C  CG  . GLU B 1 262 ? 145.156 165.242 121.340 1.00 113.39 ? 262 GLU B CG  1 
ATOM   5872  C  CD  . GLU B 1 262 ? 144.876 166.682 121.724 1.00 113.39 ? 262 GLU B CD  1 
ATOM   5873  O  OE1 . GLU B 1 262 ? 145.665 167.256 122.504 1.00 113.39 ? 262 GLU B OE1 1 
ATOM   5874  O  OE2 . GLU B 1 262 ? 143.869 167.241 121.244 1.00 113.39 ? 262 GLU B OE2 1 
ATOM   5875  N  N   . SER B 1 263 ? 142.867 164.117 123.185 1.00 115.17 ? 263 SER B N   1 
ATOM   5876  C  CA  . SER B 1 263 ? 141.587 163.435 123.027 1.00 115.17 ? 263 SER B CA  1 
ATOM   5877  C  C   . SER B 1 263 ? 141.565 162.551 121.786 1.00 115.17 ? 263 SER B C   1 
ATOM   5878  O  O   . SER B 1 263 ? 140.647 161.743 121.611 1.00 115.17 ? 263 SER B O   1 
ATOM   5879  C  CB  . SER B 1 263 ? 140.448 164.455 122.962 1.00 115.17 ? 263 SER B CB  1 
ATOM   5880  O  OG  . SER B 1 263 ? 140.549 165.259 121.800 1.00 115.17 ? 263 SER B OG  1 
ATOM   5881  N  N   . SER B 1 264 ? 142.569 162.694 120.919 1.00 115.84 ? 264 SER B N   1 
ATOM   5882  C  CA  . SER B 1 264 ? 142.575 161.933 119.674 1.00 115.84 ? 264 SER B CA  1 
ATOM   5883  C  C   . SER B 1 264 ? 143.209 160.560 119.860 1.00 115.84 ? 264 SER B C   1 
ATOM   5884  O  O   . SER B 1 264 ? 142.503 159.565 120.063 1.00 115.84 ? 264 SER B O   1 
ATOM   5885  C  CB  . SER B 1 264 ? 143.305 162.720 118.585 1.00 115.84 ? 264 SER B CB  1 
ATOM   5886  O  OG  . SER B 1 264 ? 144.675 162.881 118.906 1.00 115.84 ? 264 SER B OG  1 
ATOM   5887  N  N   . ARG B 1 265 ? 144.536 160.485 119.799 1.00 113.74 ? 265 ARG B N   1 
ATOM   5888  C  CA  . ARG B 1 265 ? 145.217 159.196 119.818 1.00 113.74 ? 265 ARG B CA  1 
ATOM   5889  C  C   . ARG B 1 265 ? 145.338 158.670 121.243 1.00 113.74 ? 265 ARG B C   1 
ATOM   5890  O  O   . ARG B 1 265 ? 144.536 159.011 122.117 1.00 113.74 ? 265 ARG B O   1 
ATOM   5891  C  CB  . ARG B 1 265 ? 146.603 159.315 119.186 1.00 113.74 ? 265 ARG B CB  1 
ATOM   5892  C  CG  . ARG B 1 265 ? 146.608 159.351 117.664 1.00 113.74 ? 265 ARG B CG  1 
ATOM   5893  C  CD  . ARG B 1 265 ? 146.372 160.761 117.144 1.00 113.74 ? 265 ARG B CD  1 
ATOM   5894  N  NE  . ARG B 1 265 ? 147.458 161.662 117.517 1.00 113.74 ? 265 ARG B NE  1 
ATOM   5895  C  CZ  . ARG B 1 265 ? 147.393 162.987 117.439 1.00 113.74 ? 265 ARG B CZ  1 
ATOM   5896  N  NH1 . ARG B 1 265 ? 146.287 163.573 117.002 1.00 113.74 ? 265 ARG B NH1 1 
ATOM   5897  N  NH2 . ARG B 1 265 ? 148.432 163.726 117.802 1.00 113.74 ? 265 ARG B NH2 1 
ATOM   5898  N  N   . THR B 1 266 ? 146.351 157.831 121.472 1.00 109.72 ? 266 THR B N   1 
ATOM   5899  C  CA  . THR B 1 266 ? 146.566 157.259 122.796 1.00 109.72 ? 266 THR B CA  1 
ATOM   5900  C  C   . THR B 1 266 ? 147.875 157.727 123.418 1.00 109.72 ? 266 THR B C   1 
ATOM   5901  O  O   . THR B 1 266 ? 148.099 157.508 124.613 1.00 109.72 ? 266 THR B O   1 
ATOM   5902  C  CB  . THR B 1 266 ? 146.541 155.731 122.722 1.00 109.72 ? 266 THR B CB  1 
ATOM   5903  O  OG1 . THR B 1 266 ? 146.588 155.185 124.046 1.00 109.72 ? 266 THR B OG1 1 
ATOM   5904  C  CG2 . THR B 1 266 ? 147.730 155.218 121.924 1.00 109.72 ? 266 THR B CG2 1 
ATOM   5905  N  N   . HIS B 1 267 ? 148.745 158.361 122.635 1.00 103.06 ? 267 HIS B N   1 
ATOM   5906  C  CA  . HIS B 1 267 ? 150.005 158.870 123.157 1.00 103.06 ? 267 HIS B CA  1 
ATOM   5907  C  C   . HIS B 1 267 ? 149.781 160.218 123.833 1.00 103.06 ? 267 HIS B C   1 
ATOM   5908  O  O   . HIS B 1 267 ? 148.755 160.869 123.615 1.00 103.06 ? 267 HIS B O   1 
ATOM   5909  C  CB  . HIS B 1 267 ? 151.035 159.000 122.037 1.00 103.06 ? 267 HIS B CB  1 
ATOM   5910  C  CG  . HIS B 1 267 ? 150.642 159.966 120.964 1.00 103.06 ? 267 HIS B CG  1 
ATOM   5911  N  ND1 . HIS B 1 267 ? 150.902 161.316 121.046 1.00 103.06 ? 267 HIS B ND1 1 
ATOM   5912  C  CD2 . HIS B 1 267 ? 150.011 159.776 119.781 1.00 103.06 ? 267 HIS B CD2 1 
ATOM   5913  C  CE1 . HIS B 1 267 ? 150.445 161.918 119.962 1.00 103.06 ? 267 HIS B CE1 1 
ATOM   5914  N  NE2 . HIS B 1 267 ? 149.900 161.005 119.178 1.00 103.06 ? 267 HIS B NE2 1 
ATOM   5915  N  N   . SER B 1 268 ? 150.745 160.634 124.650 1.00 94.87  ? 268 SER B N   1 
ATOM   5916  C  CA  . SER B 1 268 ? 150.630 161.858 125.435 1.00 94.87  ? 268 SER B CA  1 
ATOM   5917  C  C   . SER B 1 268 ? 151.613 162.890 124.894 1.00 94.87  ? 268 SER B C   1 
ATOM   5918  O  O   . SER B 1 268 ? 152.806 162.605 124.748 1.00 94.87  ? 268 SER B O   1 
ATOM   5919  C  CB  . SER B 1 268 ? 150.890 161.568 126.911 1.00 94.87  ? 268 SER B CB  1 
ATOM   5920  O  OG  . SER B 1 268 ? 149.906 160.696 127.438 1.00 94.87  ? 268 SER B OG  1 
ATOM   5921  N  N   . LEU B 1 269 ? 151.114 164.086 124.600 1.00 88.73  ? 269 LEU B N   1 
ATOM   5922  C  CA  . LEU B 1 269 ? 151.957 165.159 124.097 1.00 88.73  ? 269 LEU B CA  1 
ATOM   5923  C  C   . LEU B 1 269 ? 152.790 165.760 125.222 1.00 88.73  ? 269 LEU B C   1 
ATOM   5924  O  O   . LEU B 1 269 ? 152.555 165.502 126.405 1.00 88.73  ? 269 LEU B O   1 
ATOM   5925  C  CB  . LEU B 1 269 ? 151.112 166.251 123.440 1.00 88.73  ? 269 LEU B CB  1 
ATOM   5926  C  CG  . LEU B 1 269 ? 150.621 166.036 122.007 1.00 88.73  ? 269 LEU B CG  1 
ATOM   5927  C  CD1 . LEU B 1 269 ? 149.523 164.988 121.942 1.00 88.73  ? 269 LEU B CD1 1 
ATOM   5928  C  CD2 . LEU B 1 269 ? 150.135 167.349 121.423 1.00 88.73  ? 269 LEU B CD2 1 
ATOM   5929  N  N   . ALA B 1 270 ? 153.773 166.570 124.838 1.00 76.92  ? 270 ALA B N   1 
ATOM   5930  C  CA  . ALA B 1 270 ? 154.646 167.279 125.773 1.00 76.92  ? 270 ALA B CA  1 
ATOM   5931  C  C   . ALA B 1 270 ? 154.751 168.723 125.293 1.00 76.92  ? 270 ALA B C   1 
ATOM   5932  O  O   . ALA B 1 270 ? 155.800 169.154 124.810 1.00 76.92  ? 270 ALA B O   1 
ATOM   5933  C  CB  . ALA B 1 270 ? 156.014 166.614 125.867 1.00 76.92  ? 270 ALA B CB  1 
ATOM   5934  N  N   . VAL B 1 271 ? 153.657 169.470 125.440 1.00 78.49  ? 271 VAL B N   1 
ATOM   5935  C  CA  . VAL B 1 271 ? 153.598 170.834 124.933 1.00 78.49  ? 271 VAL B CA  1 
ATOM   5936  C  C   . VAL B 1 271 ? 154.456 171.754 125.794 1.00 78.49  ? 271 VAL B C   1 
ATOM   5937  O  O   . VAL B 1 271 ? 154.452 171.675 127.029 1.00 78.49  ? 271 VAL B O   1 
ATOM   5938  C  CB  . VAL B 1 271 ? 152.137 171.317 124.889 1.00 78.49  ? 271 VAL B CB  1 
ATOM   5939  C  CG1 . VAL B 1 271 ? 152.061 172.750 124.407 1.00 78.49  ? 271 VAL B CG1 1 
ATOM   5940  C  CG2 . VAL B 1 271 ? 151.311 170.409 124.001 1.00 78.49  ? 271 VAL B CG2 1 
ATOM   5941  N  N   . SER B 1 272 ? 155.202 172.637 125.134 1.00 82.39  ? 272 SER B N   1 
ATOM   5942  C  CA  . SER B 1 272 ? 156.042 173.638 125.787 1.00 82.39  ? 272 SER B CA  1 
ATOM   5943  C  C   . SER B 1 272 ? 155.427 175.021 125.634 1.00 82.39  ? 272 SER B C   1 
ATOM   5944  O  O   . SER B 1 272 ? 155.129 175.479 124.530 1.00 82.39  ? 272 SER B O   1 
ATOM   5945  C  CB  . SER B 1 272 ? 157.457 173.616 125.221 1.00 82.39  ? 272 SER B CB  1 
ATOM   5946  O  OG  . SER B 1 272 ? 158.264 174.610 125.827 1.00 82.39  ? 272 SER B OG  1 
ATOM   5947  N  N   . LEU B 1 273 ? 155.236 175.714 126.753 1.00 86.40  ? 273 LEU B N   1 
ATOM   5948  C  CA  . LEU B 1 273 ? 154.605 177.027 126.721 1.00 86.40  ? 273 LEU B CA  1 
ATOM   5949  C  C   . LEU B 1 273 ? 155.621 178.129 126.978 1.00 86.40  ? 273 LEU B C   1 
ATOM   5950  O  O   . LEU B 1 273 ? 155.984 178.405 128.123 1.00 86.40  ? 273 LEU B O   1 
ATOM   5951  C  CB  . LEU B 1 273 ? 153.480 177.099 127.754 1.00 86.40  ? 273 LEU B CB  1 
ATOM   5952  C  CG  . LEU B 1 273 ? 152.112 176.555 127.344 1.00 86.40  ? 273 LEU B CG  1 
ATOM   5953  C  CD1 . LEU B 1 273 ? 152.149 175.055 127.190 1.00 86.40  ? 273 LEU B CD1 1 
ATOM   5954  C  CD2 . LEU B 1 273 ? 151.070 176.950 128.369 1.00 86.40  ? 273 LEU B CD2 1 
ATOM   5955  N  N   . HIS B 1 274 ? 156.076 178.759 125.901 1.00 101.12 ? 274 HIS B N   1 
ATOM   5956  C  CA  . HIS B 1 274 ? 156.966 179.912 125.971 1.00 101.12 ? 274 HIS B CA  1 
ATOM   5957  C  C   . HIS B 1 274 ? 156.111 181.155 126.173 1.00 101.12 ? 274 HIS B C   1 
ATOM   5958  O  O   . HIS B 1 274 ? 155.478 181.640 125.228 1.00 101.12 ? 274 HIS B O   1 
ATOM   5959  C  CB  . HIS B 1 274 ? 157.814 180.028 124.708 1.00 101.12 ? 274 HIS B CB  1 
ATOM   5960  C  CG  . HIS B 1 274 ? 158.736 181.206 124.707 1.00 101.12 ? 274 HIS B CG  1 
ATOM   5961  N  ND1 . HIS B 1 274 ? 159.881 181.256 125.473 1.00 101.12 ? 274 HIS B ND1 1 
ATOM   5962  C  CD2 . HIS B 1 274 ? 158.679 182.382 124.039 1.00 101.12 ? 274 HIS B CD2 1 
ATOM   5963  C  CE1 . HIS B 1 274 ? 160.492 182.410 125.273 1.00 101.12 ? 274 HIS B CE1 1 
ATOM   5964  N  NE2 . HIS B 1 274 ? 159.783 183.112 124.407 1.00 101.12 ? 274 HIS B NE2 1 
ATOM   5965  N  N   . CYS B 1 275 ? 156.085 181.663 127.403 1.00 106.87 ? 275 CYS B N   1 
ATOM   5966  C  CA  . CYS B 1 275 ? 155.315 182.862 127.703 1.00 106.87 ? 275 CYS B CA  1 
ATOM   5967  C  C   . CYS B 1 275 ? 155.977 184.088 127.093 1.00 106.87 ? 275 CYS B C   1 
ATOM   5968  O  O   . CYS B 1 275 ? 157.206 184.175 127.016 1.00 106.87 ? 275 CYS B O   1 
ATOM   5969  C  CB  . CYS B 1 275 ? 155.177 183.031 129.217 1.00 106.87 ? 275 CYS B CB  1 
ATOM   5970  S  SG  . CYS B 1 275 ? 154.223 184.476 129.728 1.00 106.87 ? 275 CYS B SG  1 
ATOM   5971  N  N   . ALA B 1 276 ? 155.152 185.039 126.656 1.00 113.56 ? 276 ALA B N   1 
ATOM   5972  C  CA  . ALA B 1 276 ? 155.657 186.262 126.047 1.00 113.56 ? 276 ALA B CA  1 
ATOM   5973  C  C   . ALA B 1 276 ? 156.155 187.228 127.114 1.00 113.56 ? 276 ALA B C   1 
ATOM   5974  O  O   . ALA B 1 276 ? 157.007 186.871 127.933 1.00 113.56 ? 276 ALA B O   1 
ATOM   5975  C  CB  . ALA B 1 276 ? 154.575 186.922 125.190 1.00 113.56 ? 276 ALA B CB  1 
ATOM   5976  N  N   . GLU B 1 277 ? 155.629 188.452 127.115 1.00 122.05 ? 277 GLU B N   1 
ATOM   5977  C  CA  . GLU B 1 277 ? 156.039 189.441 128.103 1.00 122.05 ? 277 GLU B CA  1 
ATOM   5978  C  C   . GLU B 1 277 ? 155.066 189.477 129.274 1.00 122.05 ? 277 GLU B C   1 
ATOM   5979  O  O   . GLU B 1 277 ? 155.487 189.416 130.434 1.00 122.05 ? 277 GLU B O   1 
ATOM   5980  C  CB  . GLU B 1 277 ? 156.161 190.826 127.464 1.00 122.05 ? 277 GLU B CB  1 
ATOM   5981  C  CG  . GLU B 1 277 ? 157.319 190.950 126.485 1.00 122.05 ? 277 GLU B CG  1 
ATOM   5982  C  CD  . GLU B 1 277 ? 157.429 192.336 125.881 1.00 122.05 ? 277 GLU B CD  1 
ATOM   5983  O  OE1 . GLU B 1 277 ? 156.528 193.166 126.124 1.00 122.05 ? 277 GLU B OE1 1 
ATOM   5984  O  OE2 . GLU B 1 277 ? 158.418 192.598 125.164 1.00 122.05 ? 277 GLU B OE2 1 
ATOM   5985  N  N   . ASP B 1 278 ? 153.764 189.568 128.988 1.00 122.95 ? 278 ASP B N   1 
ATOM   5986  C  CA  . ASP B 1 278 ? 152.760 189.643 130.053 1.00 122.95 ? 278 ASP B CA  1 
ATOM   5987  C  C   . ASP B 1 278 ? 151.380 189.345 129.459 1.00 122.95 ? 278 ASP B C   1 
ATOM   5988  O  O   . ASP B 1 278 ? 151.094 189.689 128.310 1.00 122.95 ? 278 ASP B O   1 
ATOM   5989  C  CB  . ASP B 1 278 ? 152.796 190.998 130.749 1.00 122.95 ? 278 ASP B CB  1 
ATOM   5990  C  CG  . ASP B 1 278 ? 152.613 192.165 129.791 1.00 122.95 ? 278 ASP B CG  1 
ATOM   5991  O  OD1 . ASP B 1 278 ? 152.550 191.943 128.563 1.00 122.95 ? 278 ASP B OD1 1 
ATOM   5992  O  OD2 . ASP B 1 278 ? 152.533 193.315 130.271 1.00 122.95 ? 278 ASP B OD2 1 
ATOM   5993  N  N   . ASP B 1 279 ? 150.545 188.680 130.259 1.00 117.65 ? 279 ASP B N   1 
ATOM   5994  C  CA  . ASP B 1 279 ? 149.125 188.481 129.962 1.00 117.65 ? 279 ASP B CA  1 
ATOM   5995  C  C   . ASP B 1 279 ? 148.928 187.716 128.652 1.00 117.65 ? 279 ASP B C   1 
ATOM   5996  O  O   . ASP B 1 279 ? 147.954 187.914 127.922 1.00 117.65 ? 279 ASP B O   1 
ATOM   5997  C  CB  . ASP B 1 279 ? 148.390 189.825 129.943 1.00 117.65 ? 279 ASP B CB  1 
ATOM   5998  C  CG  . ASP B 1 279 ? 146.880 189.673 129.938 1.00 117.65 ? 279 ASP B CG  1 
ATOM   5999  O  OD1 . ASP B 1 279 ? 146.316 189.316 130.993 1.00 117.65 ? 279 ASP B OD1 1 
ATOM   6000  O  OD2 . ASP B 1 279 ? 146.256 189.918 128.884 1.00 117.65 ? 279 ASP B OD2 1 
ATOM   6001  N  N   . SER B 1 280 ? 149.869 186.820 128.357 1.00 112.47 ? 280 SER B N   1 
ATOM   6002  C  CA  . SER B 1 280 ? 149.790 186.003 127.153 1.00 112.47 ? 280 SER B CA  1 
ATOM   6003  C  C   . SER B 1 280 ? 150.810 184.880 127.245 1.00 112.47 ? 280 SER B C   1 
ATOM   6004  O  O   . SER B 1 280 ? 151.981 185.125 127.542 1.00 112.47 ? 280 SER B O   1 
ATOM   6005  C  CB  . SER B 1 280 ? 150.041 186.839 125.890 1.00 112.47 ? 280 SER B CB  1 
ATOM   6006  O  OG  . SER B 1 280 ? 151.372 187.322 125.853 1.00 112.47 ? 280 SER B OG  1 
ATOM   6007  N  N   . ILE B 1 281 ? 150.358 183.654 126.988 1.00 104.41 ? 281 ILE B N   1 
ATOM   6008  C  CA  . ILE B 1 281 ? 151.223 182.482 126.932 1.00 104.41 ? 281 ILE B CA  1 
ATOM   6009  C  C   . ILE B 1 281 ? 151.028 181.805 125.583 1.00 104.41 ? 281 ILE B C   1 
ATOM   6010  O  O   . ILE B 1 281 ? 149.892 181.571 125.154 1.00 104.41 ? 281 ILE B O   1 
ATOM   6011  C  CB  . ILE B 1 281 ? 150.948 181.509 128.096 1.00 104.41 ? 281 ILE B CB  1 
ATOM   6012  C  CG1 . ILE B 1 281 ? 149.478 181.086 128.124 1.00 104.41 ? 281 ILE B CG1 1 
ATOM   6013  C  CG2 . ILE B 1 281 ? 151.365 182.129 129.420 1.00 104.41 ? 281 ILE B CG2 1 
ATOM   6014  C  CD1 . ILE B 1 281 ? 149.184 179.978 129.104 1.00 104.41 ? 281 ILE B CD1 1 
ATOM   6015  N  N   . SER B 1 282 ? 152.135 181.508 124.911 1.00 100.30 ? 282 SER B N   1 
ATOM   6016  C  CA  . SER B 1 282 ? 152.102 180.935 123.574 1.00 100.30 ? 282 SER B CA  1 
ATOM   6017  C  C   . SER B 1 282 ? 152.470 179.453 123.653 1.00 100.30 ? 282 SER B C   1 
ATOM   6018  O  O   . SER B 1 282 ? 152.465 178.855 124.732 1.00 100.30 ? 282 SER B O   1 
ATOM   6019  C  CB  . SER B 1 282 ? 153.033 181.724 122.650 1.00 100.30 ? 282 SER B CB  1 
ATOM   6020  O  OG  . SER B 1 282 ? 154.382 181.576 123.054 1.00 100.30 ? 282 SER B OG  1 
ATOM   6021  N  N   . VAL B 1 283 ? 152.788 178.843 122.515 1.00 96.33  ? 283 VAL B N   1 
ATOM   6022  C  CA  . VAL B 1 283 ? 153.161 177.434 122.460 1.00 96.33  ? 283 VAL B CA  1 
ATOM   6023  C  C   . VAL B 1 283 ? 154.371 177.288 121.552 1.00 96.33  ? 283 VAL B C   1 
ATOM   6024  O  O   . VAL B 1 283 ? 154.360 177.754 120.409 1.00 96.33  ? 283 VAL B O   1 
ATOM   6025  C  CB  . VAL B 1 283 ? 152.004 176.547 121.961 1.00 96.33  ? 283 VAL B CB  1 
ATOM   6026  C  CG1 . VAL B 1 283 ? 152.491 175.129 121.738 1.00 96.33  ? 283 VAL B CG1 1 
ATOM   6027  C  CG2 . VAL B 1 283 ? 150.861 176.560 122.955 1.00 96.33  ? 283 VAL B CG2 1 
ATOM   6028  N  N   . SER B 1 284 ? 155.415 176.636 122.059 1.00 92.96  ? 284 SER B N   1 
ATOM   6029  C  CA  . SER B 1 284 ? 156.599 176.369 121.255 1.00 92.96  ? 284 SER B CA  1 
ATOM   6030  C  C   . SER B 1 284 ? 156.367 175.161 120.360 1.00 92.96  ? 284 SER B C   1 
ATOM   6031  O  O   . SER B 1 284 ? 155.708 175.269 119.320 1.00 92.96  ? 284 SER B O   1 
ATOM   6032  C  CB  . SER B 1 284 ? 157.818 176.145 122.149 1.00 92.96  ? 284 SER B CB  1 
ATOM   6033  O  OG  . SER B 1 284 ? 158.131 177.316 122.881 1.00 92.96  ? 284 SER B OG  1 
ATOM   6034  N  N   . GLY B 1 285 ? 156.894 174.009 120.756 1.00 90.78  ? 285 GLY B N   1 
ATOM   6035  C  CA  . GLY B 1 285 ? 156.780 172.818 119.948 1.00 90.78  ? 285 GLY B CA  1 
ATOM   6036  C  C   . GLY B 1 285 ? 156.161 171.658 120.709 1.00 90.78  ? 285 GLY B C   1 
ATOM   6037  O  O   . GLY B 1 285 ? 155.771 171.753 121.873 1.00 90.78  ? 285 GLY B O   1 
ATOM   6038  N  N   . GLN B 1 286 ? 156.075 170.529 120.009 1.00 88.57  ? 286 GLN B N   1 
ATOM   6039  C  CA  . GLN B 1 286 ? 155.518 169.306 120.572 1.00 88.57  ? 286 GLN B CA  1 
ATOM   6040  C  C   . GLN B 1 286 ? 156.507 168.161 120.405 1.00 88.57  ? 286 GLN B C   1 
ATOM   6041  O  O   . GLN B 1 286 ? 157.474 168.280 119.647 1.00 88.57  ? 286 GLN B O   1 
ATOM   6042  C  CB  . GLN B 1 286 ? 154.187 168.967 119.903 1.00 88.57  ? 286 GLN B CB  1 
ATOM   6043  C  CG  . GLN B 1 286 ? 153.090 169.977 120.167 1.00 88.57  ? 286 GLN B CG  1 
ATOM   6044  C  CD  . GLN B 1 286 ? 151.809 169.644 119.433 1.00 88.57  ? 286 GLN B CD  1 
ATOM   6045  O  OE1 . GLN B 1 286 ? 151.753 168.686 118.664 1.00 88.57  ? 286 GLN B OE1 1 
ATOM   6046  N  NE2 . GLN B 1 286 ? 150.771 170.435 119.667 1.00 88.57  ? 286 GLN B NE2 1 
ATOM   6047  N  N   . ASN B 1 287 ? 156.274 167.047 121.098 1.00 85.43  ? 287 ASN B N   1 
ATOM   6048  C  CA  . ASN B 1 287 ? 157.205 165.926 121.051 1.00 85.43  ? 287 ASN B CA  1 
ATOM   6049  C  C   . ASN B 1 287 ? 156.513 164.572 121.064 1.00 85.43  ? 287 ASN B C   1 
ATOM   6050  O  O   . ASN B 1 287 ? 156.897 163.686 120.291 1.00 85.43  ? 287 ASN B O   1 
ATOM   6051  C  CB  . ASN B 1 287 ? 158.180 166.004 122.228 1.00 85.43  ? 287 ASN B CB  1 
ATOM   6052  C  CG  . ASN B 1 287 ? 159.180 167.132 122.083 1.00 85.43  ? 287 ASN B CG  1 
ATOM   6053  O  OD1 . ASN B 1 287 ? 159.740 167.346 121.010 1.00 85.43  ? 287 ASN B OD1 1 
ATOM   6054  N  ND2 . ASN B 1 287 ? 159.405 167.866 123.167 1.00 85.43  ? 287 ASN B ND2 1 
ATOM   6055  N  N   . SER B 1 288 ? 155.515 164.390 121.933 1.00 86.65  ? 288 SER B N   1 
ATOM   6056  C  CA  . SER B 1 288 ? 154.806 163.122 122.119 1.00 86.65  ? 288 SER B CA  1 
ATOM   6057  C  C   . SER B 1 288 ? 155.756 162.039 122.645 1.00 86.65  ? 288 SER B C   1 
ATOM   6058  O  O   . SER B 1 288 ? 156.982 162.161 122.619 1.00 86.65  ? 288 SER B O   1 
ATOM   6059  C  CB  . SER B 1 288 ? 154.115 162.679 120.823 1.00 86.65  ? 288 SER B CB  1 
ATOM   6060  O  OG  . SER B 1 288 ? 153.461 161.434 120.993 1.00 86.65  ? 288 SER B OG  1 
ATOM   6061  N  N   . LEU B 1 289 ? 155.141 160.968 123.139 1.00 85.13  ? 289 LEU B N   1 
ATOM   6062  C  CA  . LEU B 1 289 ? 155.913 159.861 123.685 1.00 85.13  ? 289 LEU B CA  1 
ATOM   6063  C  C   . LEU B 1 289 ? 155.111 158.568 123.619 1.00 85.13  ? 289 LEU B C   1 
ATOM   6064  O  O   . LEU B 1 289 ? 153.921 158.536 123.944 1.00 85.13  ? 289 LEU B O   1 
ATOM   6065  C  CB  . LEU B 1 289 ? 156.320 160.160 125.129 1.00 85.13  ? 289 LEU B CB  1 
ATOM   6066  C  CG  . LEU B 1 289 ? 157.214 159.129 125.823 1.00 85.13  ? 289 LEU B CG  1 
ATOM   6067  C  CD1 . LEU B 1 289 ? 158.551 158.998 125.109 1.00 85.13  ? 289 LEU B CD1 1 
ATOM   6068  C  CD2 . LEU B 1 289 ? 157.419 159.497 127.282 1.00 85.13  ? 289 LEU B CD2 1 
ATOM   6069  N  N   . CYS B 1 290 ? 155.776 157.494 123.194 1.00 85.03  ? 290 CYS B N   1 
ATOM   6070  C  CA  . CYS B 1 290 ? 155.114 156.200 123.072 1.00 85.03  ? 290 CYS B CA  1 
ATOM   6071  C  C   . CYS B 1 290 ? 154.808 155.591 124.435 1.00 85.03  ? 290 CYS B C   1 
ATOM   6072  O  O   . CYS B 1 290 ? 153.900 154.761 124.558 1.00 85.03  ? 290 CYS B O   1 
ATOM   6073  C  CB  . CYS B 1 290 ? 155.981 155.246 122.251 1.00 85.03  ? 290 CYS B CB  1 
ATOM   6074  S  SG  . CYS B 1 290 ? 155.252 153.617 121.989 1.00 85.03  ? 290 CYS B SG  1 
ATOM   6075  N  N   . HIS B 1 291 ? 155.544 155.995 125.465 1.00 75.98  ? 291 HIS B N   1 
ATOM   6076  C  CA  . HIS B 1 291 ? 155.427 155.364 126.769 1.00 75.98  ? 291 HIS B CA  1 
ATOM   6077  C  C   . HIS B 1 291 ? 154.412 156.111 127.629 1.00 75.98  ? 291 HIS B C   1 
ATOM   6078  O  O   . HIS B 1 291 ? 153.950 157.205 127.296 1.00 75.98  ? 291 HIS B O   1 
ATOM   6079  C  CB  . HIS B 1 291 ? 156.788 155.331 127.458 1.00 75.98  ? 291 HIS B CB  1 
ATOM   6080  C  CG  . HIS B 1 291 ? 157.838 154.600 126.684 1.00 75.98  ? 291 HIS B CG  1 
ATOM   6081  N  ND1 . HIS B 1 291 ? 158.636 155.222 125.749 1.00 75.98  ? 291 HIS B ND1 1 
ATOM   6082  C  CD2 . HIS B 1 291 ? 158.222 153.303 126.703 1.00 75.98  ? 291 HIS B CD2 1 
ATOM   6083  C  CE1 . HIS B 1 291 ? 159.466 154.340 125.224 1.00 75.98  ? 291 HIS B CE1 1 
ATOM   6084  N  NE2 . HIS B 1 291 ? 159.236 153.167 125.787 1.00 75.98  ? 291 HIS B NE2 1 
ATOM   6085  N  N   . GLN B 1 292 ? 154.057 155.502 128.753 1.00 78.22  ? 292 GLN B N   1 
ATOM   6086  C  CA  . GLN B 1 292 ? 153.330 156.202 129.796 1.00 78.22  ? 292 GLN B CA  1 
ATOM   6087  C  C   . GLN B 1 292 ? 154.311 156.978 130.669 1.00 78.22  ? 292 GLN B C   1 
ATOM   6088  O  O   . GLN B 1 292 ? 155.527 156.928 130.477 1.00 78.22  ? 292 GLN B O   1 
ATOM   6089  C  CB  . GLN B 1 292 ? 152.512 155.224 130.638 1.00 78.22  ? 292 GLN B CB  1 
ATOM   6090  C  CG  . GLN B 1 292 ? 151.366 154.569 129.889 1.00 78.22  ? 292 GLN B CG  1 
ATOM   6091  C  CD  . GLN B 1 292 ? 150.325 155.571 129.428 1.00 78.22  ? 292 GLN B CD  1 
ATOM   6092  O  OE1 . GLN B 1 292 ? 150.201 155.852 128.235 1.00 78.22  ? 292 GLN B OE1 1 
ATOM   6093  N  NE2 . GLN B 1 292 ? 149.570 156.115 130.374 1.00 78.22  ? 292 GLN B NE2 1 
ATOM   6094  N  N   . ILE B 1 293 ? 153.769 157.710 131.637 1.00 66.65  ? 293 ILE B N   1 
ATOM   6095  C  CA  . ILE B 1 293 ? 154.566 158.527 132.542 1.00 66.65  ? 293 ILE B CA  1 
ATOM   6096  C  C   . ILE B 1 293 ? 154.006 158.384 133.947 1.00 66.65  ? 293 ILE B C   1 
ATOM   6097  O  O   . ILE B 1 293 ? 152.809 158.600 134.167 1.00 66.65  ? 293 ILE B O   1 
ATOM   6098  C  CB  . ILE B 1 293 ? 154.582 160.007 132.117 1.00 66.65  ? 293 ILE B CB  1 
ATOM   6099  C  CG1 . ILE B 1 293 ? 155.303 160.176 130.780 1.00 66.65  ? 293 ILE B CG1 1 
ATOM   6100  C  CG2 . ILE B 1 293 ? 155.243 160.857 133.179 1.00 66.65  ? 293 ILE B CG2 1 
ATOM   6101  C  CD1 . ILE B 1 293 ? 155.140 161.543 130.174 1.00 66.65  ? 293 ILE B CD1 1 
ATOM   6102  N  N   . THR B 1 294 ? 154.868 158.013 134.894 1.00 61.36  ? 294 THR B N   1 
ATOM   6103  C  CA  . THR B 1 294 ? 154.497 157.948 136.298 1.00 61.36  ? 294 THR B CA  1 
ATOM   6104  C  C   . THR B 1 294 ? 154.995 159.141 137.101 1.00 61.36  ? 294 THR B C   1 
ATOM   6105  O  O   . THR B 1 294 ? 154.554 159.324 138.240 1.00 61.36  ? 294 THR B O   1 
ATOM   6106  C  CB  . THR B 1 294 ? 155.026 156.653 136.933 1.00 61.36  ? 294 THR B CB  1 
ATOM   6107  O  OG1 . THR B 1 294 ? 156.456 156.646 136.893 1.00 61.36  ? 294 THR B OG1 1 
ATOM   6108  C  CG2 . THR B 1 294 ? 154.510 155.444 136.174 1.00 61.36  ? 294 THR B CG2 1 
ATOM   6109  N  N   . ALA B 1 295 ? 155.888 159.951 136.537 1.00 54.02  ? 295 ALA B N   1 
ATOM   6110  C  CA  . ALA B 1 295 ? 156.403 161.159 137.168 1.00 54.02  ? 295 ALA B CA  1 
ATOM   6111  C  C   . ALA B 1 295 ? 157.211 161.921 136.129 1.00 54.02  ? 295 ALA B C   1 
ATOM   6112  O  O   . ALA B 1 295 ? 157.719 161.335 135.171 1.00 54.02  ? 295 ALA B O   1 
ATOM   6113  C  CB  . ALA B 1 295 ? 157.264 160.841 138.393 1.00 54.02  ? 295 ALA B CB  1 
ATOM   6114  N  N   . ALA B 1 296 ? 157.325 163.232 136.328 1.00 55.21  ? 296 ALA B N   1 
ATOM   6115  C  CA  . ALA B 1 296 ? 158.067 164.073 135.401 1.00 55.21  ? 296 ALA B CA  1 
ATOM   6116  C  C   . ALA B 1 296 ? 158.471 165.356 136.109 1.00 55.21  ? 296 ALA B C   1 
ATOM   6117  O  O   . ALA B 1 296 ? 157.738 165.851 136.968 1.00 55.21  ? 296 ALA B O   1 
ATOM   6118  C  CB  . ALA B 1 296 ? 157.241 164.392 134.151 1.00 55.21  ? 296 ALA B CB  1 
ATOM   6119  N  N   . CYS B 1 297 ? 159.638 165.886 135.748 1.00 58.20  ? 297 CYS B N   1 
ATOM   6120  C  CA  . CYS B 1 297 ? 160.145 167.124 136.323 1.00 58.20  ? 297 CYS B CA  1 
ATOM   6121  C  C   . CYS B 1 297 ? 160.820 167.956 135.240 1.00 58.20  ? 297 CYS B C   1 
ATOM   6122  O  O   . CYS B 1 297 ? 161.128 167.472 134.146 1.00 58.20  ? 297 CYS B O   1 
ATOM   6123  C  CB  . CYS B 1 297 ? 161.121 166.851 137.473 1.00 58.20  ? 297 CYS B CB  1 
ATOM   6124  S  SG  . CYS B 1 297 ? 162.680 166.104 136.974 1.00 58.20  ? 297 CYS B SG  1 
ATOM   6125  N  N   . LYS B 1 298 ? 161.058 169.223 135.568 1.00 64.32  ? 298 LYS B N   1 
ATOM   6126  C  CA  . LYS B 1 298 ? 161.719 170.179 134.686 1.00 64.32  ? 298 LYS B CA  1 
ATOM   6127  C  C   . LYS B 1 298 ? 162.979 170.678 135.375 1.00 64.32  ? 298 LYS B C   1 
ATOM   6128  O  O   . LYS B 1 298 ? 162.899 171.334 136.419 1.00 64.32  ? 298 LYS B O   1 
ATOM   6129  C  CB  . LYS B 1 298 ? 160.794 171.345 134.351 1.00 64.32  ? 298 LYS B CB  1 
ATOM   6130  C  CG  . LYS B 1 298 ? 161.447 172.415 133.511 1.00 64.32  ? 298 LYS B CG  1 
ATOM   6131  C  CD  . LYS B 1 298 ? 160.485 173.540 133.194 1.00 64.32  ? 298 LYS B CD  1 
ATOM   6132  C  CE  . LYS B 1 298 ? 161.170 174.610 132.368 1.00 64.32  ? 298 LYS B CE  1 
ATOM   6133  N  NZ  . LYS B 1 298 ? 162.209 175.323 133.157 1.00 64.32  ? 298 LYS B NZ  1 
ATOM   6134  N  N   . HIS B 1 299 ? 164.136 170.380 134.793 1.00 64.25  ? 299 HIS B N   1 
ATOM   6135  C  CA  . HIS B 1 299 ? 165.423 170.770 135.356 1.00 64.25  ? 299 HIS B CA  1 
ATOM   6136  C  C   . HIS B 1 299 ? 166.136 171.697 134.381 1.00 64.25  ? 299 HIS B C   1 
ATOM   6137  O  O   . HIS B 1 299 ? 166.553 171.268 133.300 1.00 64.25  ? 299 HIS B O   1 
ATOM   6138  C  CB  . HIS B 1 299 ? 166.278 169.543 135.658 1.00 64.25  ? 299 HIS B CB  1 
ATOM   6139  C  CG  . HIS B 1 299 ? 167.595 169.869 136.289 1.00 64.25  ? 299 HIS B CG  1 
ATOM   6140  N  ND1 . HIS B 1 299 ? 167.711 170.277 137.600 1.00 64.25  ? 299 HIS B ND1 1 
ATOM   6141  C  CD2 . HIS B 1 299 ? 168.853 169.847 135.790 1.00 64.25  ? 299 HIS B CD2 1 
ATOM   6142  C  CE1 . HIS B 1 299 ? 168.983 170.494 137.881 1.00 64.25  ? 299 HIS B CE1 1 
ATOM   6143  N  NE2 . HIS B 1 299 ? 169.697 170.240 136.800 1.00 64.25  ? 299 HIS B NE2 1 
ATOM   6144  N  N   . GLY B 1 300 ? 166.278 172.963 134.768 1.00 71.93  ? 300 GLY B N   1 
ATOM   6145  C  CA  . GLY B 1 300 ? 167.049 173.927 134.008 1.00 71.93  ? 300 GLY B CA  1 
ATOM   6146  C  C   . GLY B 1 300 ? 166.641 174.068 132.558 1.00 71.93  ? 300 GLY B C   1 
ATOM   6147  O  O   . GLY B 1 300 ? 167.487 174.300 131.690 1.00 71.93  ? 300 GLY B O   1 
ATOM   6148  N  N   . GLY B 1 301 ? 165.350 173.924 132.278 1.00 70.14  ? 301 GLY B N   1 
ATOM   6149  C  CA  . GLY B 1 301 ? 164.861 174.081 130.924 1.00 70.14  ? 301 GLY B CA  1 
ATOM   6150  C  C   . GLY B 1 301 ? 164.774 172.784 130.147 1.00 70.14  ? 301 GLY B C   1 
ATOM   6151  O  O   . GLY B 1 301 ? 164.277 172.769 129.017 1.00 70.14  ? 301 GLY B O   1 
ATOM   6152  N  N   . ASP B 1 302 ? 165.253 171.692 130.735 1.00 70.11  ? 302 ASP B N   1 
ATOM   6153  C  CA  . ASP B 1 302 ? 165.192 170.372 130.123 1.00 70.11  ? 302 ASP B CA  1 
ATOM   6154  C  C   . ASP B 1 302 ? 164.125 169.531 130.809 1.00 70.11  ? 302 ASP B C   1 
ATOM   6155  O  O   . ASP B 1 302 ? 163.922 169.638 132.020 1.00 70.11  ? 302 ASP B O   1 
ATOM   6156  C  CB  . ASP B 1 302 ? 166.546 169.663 130.204 1.00 70.11  ? 302 ASP B CB  1 
ATOM   6157  C  CG  . ASP B 1 302 ? 167.580 170.277 129.284 1.00 70.11  ? 302 ASP B CG  1 
ATOM   6158  O  OD1 . ASP B 1 302 ? 167.193 170.809 128.223 1.00 70.11  ? 302 ASP B OD1 1 
ATOM   6159  O  OD2 . ASP B 1 302 ? 168.782 170.230 129.623 1.00 70.11  ? 302 ASP B OD2 1 
ATOM   6160  N  N   . LEU B 1 303 ? 163.445 168.695 130.031 1.00 62.33  ? 303 LEU B N   1 
ATOM   6161  C  CA  . LEU B 1 303 ? 162.361 167.862 130.535 1.00 62.33  ? 303 LEU B CA  1 
ATOM   6162  C  C   . LEU B 1 303 ? 162.905 166.492 130.914 1.00 62.33  ? 303 LEU B C   1 
ATOM   6163  O  O   . LEU B 1 303 ? 163.772 165.952 130.221 1.00 62.33  ? 303 LEU B O   1 
ATOM   6164  C  CB  . LEU B 1 303 ? 161.255 167.727 129.489 1.00 62.33  ? 303 LEU B CB  1 
ATOM   6165  C  CG  . LEU B 1 303 ? 160.005 166.952 129.898 1.00 62.33  ? 303 LEU B CG  1 
ATOM   6166  C  CD1 . LEU B 1 303 ? 159.343 167.621 131.077 1.00 62.33  ? 303 LEU B CD1 1 
ATOM   6167  C  CD2 . LEU B 1 303 ? 159.037 166.859 128.735 1.00 62.33  ? 303 LEU B CD2 1 
ATOM   6168  N  N   . TYR B 1 304 ? 162.399 165.935 132.010 1.00 56.06  ? 304 TYR B N   1 
ATOM   6169  C  CA  . TYR B 1 304 ? 162.826 164.634 132.511 1.00 56.06  ? 304 TYR B CA  1 
ATOM   6170  C  C   . TYR B 1 304 ? 161.608 163.813 132.906 1.00 56.06  ? 304 TYR B C   1 
ATOM   6171  O  O   . TYR B 1 304 ? 161.012 164.057 133.960 1.00 56.06  ? 304 TYR B O   1 
ATOM   6172  C  CB  . TYR B 1 304 ? 163.759 164.790 133.713 1.00 56.06  ? 304 TYR B CB  1 
ATOM   6173  C  CG  . TYR B 1 304 ? 165.130 165.323 133.380 1.00 56.06  ? 304 TYR B CG  1 
ATOM   6174  C  CD1 . TYR B 1 304 ? 166.146 164.474 132.985 1.00 56.06  ? 304 TYR B CD1 1 
ATOM   6175  C  CD2 . TYR B 1 304 ? 165.402 166.676 133.447 1.00 56.06  ? 304 TYR B CD2 1 
ATOM   6176  C  CE1 . TYR B 1 304 ? 167.398 164.955 132.683 1.00 56.06  ? 304 TYR B CE1 1 
ATOM   6177  C  CE2 . TYR B 1 304 ? 166.649 167.167 133.137 1.00 56.06  ? 304 TYR B CE2 1 
ATOM   6178  C  CZ  . TYR B 1 304 ? 167.645 166.301 132.758 1.00 56.06  ? 304 TYR B CZ  1 
ATOM   6179  O  OH  . TYR B 1 304 ? 168.893 166.786 132.449 1.00 56.06  ? 304 TYR B OH  1 
ATOM   6180  N  N   . VAL B 1 305 ? 161.246 162.840 132.073 1.00 54.78  ? 305 VAL B N   1 
ATOM   6181  C  CA  . VAL B 1 305 ? 160.085 161.992 132.323 1.00 54.78  ? 305 VAL B CA  1 
ATOM   6182  C  C   . VAL B 1 305 ? 160.573 160.644 132.832 1.00 54.78  ? 305 VAL B C   1 
ATOM   6183  O  O   . VAL B 1 305 ? 161.693 160.227 132.520 1.00 54.78  ? 305 VAL B O   1 
ATOM   6184  C  CB  . VAL B 1 305 ? 159.211 161.817 131.067 1.00 54.78  ? 305 VAL B CB  1 
ATOM   6185  C  CG1 . VAL B 1 305 ? 158.671 163.157 130.607 1.00 54.78  ? 305 VAL B CG1 1 
ATOM   6186  C  CG2 . VAL B 1 305 ? 159.994 161.148 129.960 1.00 54.78  ? 305 VAL B CG2 1 
ATOM   6187  N  N   . VAL B 1 306 ? 159.739 159.970 133.620 1.00 54.86  ? 306 VAL B N   1 
ATOM   6188  C  CA  . VAL B 1 306 ? 160.078 158.702 134.254 1.00 54.86  ? 306 VAL B CA  1 
ATOM   6189  C  C   . VAL B 1 306 ? 158.884 157.767 134.149 1.00 54.86  ? 306 VAL B C   1 
ATOM   6190  O  O   . VAL B 1 306 ? 157.740 158.179 134.369 1.00 54.86  ? 306 VAL B O   1 
ATOM   6191  C  CB  . VAL B 1 306 ? 160.480 158.896 135.730 1.00 54.86  ? 306 VAL B CB  1 
ATOM   6192  C  CG1 . VAL B 1 306 ? 160.660 157.556 136.411 1.00 54.86  ? 306 VAL B CG1 1 
ATOM   6193  C  CG2 . VAL B 1 306 ? 161.752 159.709 135.836 1.00 54.86  ? 306 VAL B CG2 1 
ATOM   6194  N  N   . GLY B 1 307 ? 159.148 156.512 133.808 1.00 64.26  ? 307 GLY B N   1 
ATOM   6195  C  CA  . GLY B 1 307 ? 158.121 155.486 133.850 1.00 64.26  ? 307 GLY B CA  1 
ATOM   6196  C  C   . GLY B 1 307 ? 157.882 154.792 132.526 1.00 64.26  ? 307 GLY B C   1 
ATOM   6197  O  O   . GLY B 1 307 ? 158.246 155.291 131.459 1.00 64.26  ? 307 GLY B O   1 
ATOM   6198  N  N   . GLY B 1 308 ? 157.258 153.617 132.597 1.00 74.83  ? 308 GLY B N   1 
ATOM   6199  C  CA  . GLY B 1 308 ? 156.907 152.873 131.411 1.00 74.83  ? 308 GLY B CA  1 
ATOM   6200  C  C   . GLY B 1 308 ? 155.575 152.173 131.593 1.00 74.83  ? 308 GLY B C   1 
ATOM   6201  O  O   . GLY B 1 308 ? 155.173 151.825 132.704 1.00 74.83  ? 308 GLY B O   1 
ATOM   6202  N  N   . SER B 1 309 ? 154.885 151.974 130.467 1.00 81.25  ? 309 SER B N   1 
ATOM   6203  C  CA  . SER B 1 309 ? 153.585 151.314 130.489 1.00 81.25  ? 309 SER B CA  1 
ATOM   6204  C  C   . SER B 1 309 ? 153.669 149.866 130.954 1.00 81.25  ? 309 SER B C   1 
ATOM   6205  O  O   . SER B 1 309 ? 152.654 149.310 131.386 1.00 81.25  ? 309 SER B O   1 
ATOM   6206  C  CB  . SER B 1 309 ? 152.937 151.373 129.103 1.00 81.25  ? 309 SER B CB  1 
ATOM   6207  O  OG  . SER B 1 309 ? 153.669 150.617 128.155 1.00 81.25  ? 309 SER B OG  1 
ATOM   6208  N  N   . THR B 1 310 ? 154.847 149.250 130.881 1.00 80.76  ? 310 THR B N   1 
ATOM   6209  C  CA  . THR B 1 310 ? 155.028 147.881 131.345 1.00 80.76  ? 310 THR B CA  1 
ATOM   6210  C  C   . THR B 1 310 ? 155.107 147.844 132.865 1.00 80.76  ? 310 THR B C   1 
ATOM   6211  O  O   . THR B 1 310 ? 154.540 148.706 133.544 1.00 80.76  ? 310 THR B O   1 
ATOM   6212  C  CB  . THR B 1 310 ? 156.286 147.264 130.729 1.00 80.76  ? 310 THR B CB  1 
ATOM   6213  O  OG1 . THR B 1 310 ? 157.440 148.003 131.148 1.00 80.76  ? 310 THR B OG1 1 
ATOM   6214  C  CG2 . THR B 1 310 ? 156.200 147.290 129.210 1.00 80.76  ? 310 THR B CG2 1 
ATOM   6215  N  N   . THR B 1 311 ? 155.807 146.850 133.412 1.00 80.48  ? 311 THR B N   1 
ATOM   6216  C  CA  . THR B 1 311 ? 155.961 146.716 134.855 1.00 80.48  ? 311 THR B CA  1 
ATOM   6217  C  C   . THR B 1 311 ? 157.400 147.000 135.283 1.00 80.48  ? 311 THR B C   1 
ATOM   6218  O  O   . THR B 1 311 ? 157.732 146.915 136.469 1.00 80.48  ? 311 THR B O   1 
ATOM   6219  C  CB  . THR B 1 311 ? 155.504 145.324 135.302 1.00 80.48  ? 311 THR B CB  1 
ATOM   6220  O  OG1 . THR B 1 311 ? 154.217 145.057 134.738 1.00 80.48  ? 311 THR B OG1 1 
ATOM   6221  C  CG2 . THR B 1 311 ? 155.350 145.247 136.816 1.00 80.48  ? 311 THR B CG2 1 
ATOM   6222  N  N   . TYR B 1 312 ? 158.265 147.358 134.339 1.00 78.23  ? 312 TYR B N   1 
ATOM   6223  C  CA  . TYR B 1 312 ? 159.611 147.828 134.658 1.00 78.23  ? 312 TYR B CA  1 
ATOM   6224  C  C   . TYR B 1 312 ? 159.598 149.341 134.478 1.00 78.23  ? 312 TYR B C   1 
ATOM   6225  O  O   . TYR B 1 312 ? 159.843 149.841 133.376 1.00 78.23  ? 312 TYR B O   1 
ATOM   6226  C  CB  . TYR B 1 312 ? 160.675 147.177 133.780 1.00 78.23  ? 312 TYR B CB  1 
ATOM   6227  C  CG  . TYR B 1 312 ? 160.840 145.687 133.974 1.00 78.23  ? 312 TYR B CG  1 
ATOM   6228  C  CD1 . TYR B 1 312 ? 160.181 145.016 134.992 1.00 78.23  ? 312 TYR B CD1 1 
ATOM   6229  C  CD2 . TYR B 1 312 ? 161.686 144.956 133.151 1.00 78.23  ? 312 TYR B CD2 1 
ATOM   6230  C  CE1 . TYR B 1 312 ? 160.335 143.656 135.159 1.00 78.23  ? 312 TYR B CE1 1 
ATOM   6231  C  CE2 . TYR B 1 312 ? 161.856 143.607 133.321 1.00 78.23  ? 312 TYR B CE2 1 
ATOM   6232  C  CZ  . TYR B 1 312 ? 161.182 142.960 134.326 1.00 78.23  ? 312 TYR B CZ  1 
ATOM   6233  O  OH  . TYR B 1 312 ? 161.358 141.606 134.480 1.00 78.23  ? 312 TYR B OH  1 
ATOM   6234  N  N   . MET B 1 313 ? 159.298 150.066 135.550 1.00 69.61  ? 313 MET B N   1 
ATOM   6235  C  CA  . MET B 1 313 ? 159.277 151.522 135.532 1.00 69.61  ? 313 MET B CA  1 
ATOM   6236  C  C   . MET B 1 313 ? 160.608 152.057 136.055 1.00 69.61  ? 313 MET B C   1 
ATOM   6237  O  O   . MET B 1 313 ? 160.674 153.020 136.821 1.00 69.61  ? 313 MET B O   1 
ATOM   6238  C  CB  . MET B 1 313 ? 158.076 152.045 136.331 1.00 69.61  ? 313 MET B CB  1 
ATOM   6239  C  CG  . MET B 1 313 ? 158.086 151.683 137.801 1.00 69.61  ? 313 MET B CG  1 
ATOM   6240  S  SD  . MET B 1 313 ? 157.712 149.939 138.037 1.00 69.61  ? 313 MET B SD  1 
ATOM   6241  C  CE  . MET B 1 313 ? 155.990 149.919 137.545 1.00 69.61  ? 313 MET B CE  1 
ATOM   6242  N  N   . LEU B 1 314 ? 161.689 151.412 135.619 1.00 60.51  ? 314 LEU B N   1 
ATOM   6243  C  CA  . LEU B 1 314 ? 163.038 151.925 135.809 1.00 60.51  ? 314 LEU B CA  1 
ATOM   6244  C  C   . LEU B 1 314 ? 163.341 153.099 134.892 1.00 60.51  ? 314 LEU B C   1 
ATOM   6245  O  O   . LEU B 1 314 ? 164.119 153.985 135.255 1.00 60.51  ? 314 LEU B O   1 
ATOM   6246  C  CB  . LEU B 1 314 ? 164.079 150.833 135.534 1.00 60.51  ? 314 LEU B CB  1 
ATOM   6247  C  CG  . LEU B 1 314 ? 164.340 149.627 136.436 1.00 60.51  ? 314 LEU B CG  1 
ATOM   6248  C  CD1 . LEU B 1 314 ? 164.376 150.045 137.887 1.00 60.51  ? 314 LEU B CD1 1 
ATOM   6249  C  CD2 . LEU B 1 314 ? 163.294 148.551 136.215 1.00 60.51  ? 314 LEU B CD2 1 
ATOM   6250  N  N   . ARG B 1 315 ? 162.724 153.120 133.714 1.00 57.40  ? 315 ARG B N   1 
ATOM   6251  C  CA  . ARG B 1 315 ? 163.209 153.895 132.581 1.00 57.40  ? 315 ARG B CA  1 
ATOM   6252  C  C   . ARG B 1 315 ? 163.010 155.389 132.796 1.00 57.40  ? 315 ARG B C   1 
ATOM   6253  O  O   . ARG B 1 315 ? 162.196 155.808 133.622 1.00 57.40  ? 315 ARG B O   1 
ATOM   6254  C  CB  . ARG B 1 315 ? 162.484 153.427 131.318 1.00 57.40  ? 315 ARG B CB  1 
ATOM   6255  C  CG  . ARG B 1 315 ? 162.674 151.936 131.087 1.00 57.40  ? 315 ARG B CG  1 
ATOM   6256  C  CD  . ARG B 1 315 ? 161.930 151.387 129.884 1.00 57.40  ? 315 ARG B CD  1 
ATOM   6257  N  NE  . ARG B 1 315 ? 162.543 151.765 128.617 1.00 57.40  ? 315 ARG B NE  1 
ATOM   6258  C  CZ  . ARG B 1 315 ? 162.016 151.491 127.429 1.00 57.40  ? 315 ARG B CZ  1 
ATOM   6259  N  NH1 . ARG B 1 315 ? 160.865 150.841 127.350 1.00 57.40  ? 315 ARG B NH1 1 
ATOM   6260  N  NH2 . ARG B 1 315 ? 162.639 151.867 126.321 1.00 57.40  ? 315 ARG B NH2 1 
ATOM   6261  N  N   . MET B 1 316 ? 163.768 156.191 132.049 1.00 57.31  ? 316 MET B N   1 
ATOM   6262  C  CA  . MET B 1 316 ? 163.772 157.638 132.200 1.00 57.31  ? 316 MET B CA  1 
ATOM   6263  C  C   . MET B 1 316 ? 164.253 158.282 130.910 1.00 57.31  ? 316 MET B C   1 
ATOM   6264  O  O   . MET B 1 316 ? 165.190 157.788 130.278 1.00 57.31  ? 316 MET B O   1 
ATOM   6265  C  CB  . MET B 1 316 ? 164.670 158.061 133.366 1.00 57.31  ? 316 MET B CB  1 
ATOM   6266  C  CG  . MET B 1 316 ? 164.674 159.548 133.646 1.00 57.31  ? 316 MET B CG  1 
ATOM   6267  S  SD  . MET B 1 316 ? 165.647 159.954 135.101 1.00 57.31  ? 316 MET B SD  1 
ATOM   6268  C  CE  . MET B 1 316 ? 165.507 161.733 135.106 1.00 57.31  ? 316 MET B CE  1 
ATOM   6269  N  N   . TRP B 1 317 ? 163.616 159.387 130.523 1.00 60.15  ? 317 TRP B N   1 
ATOM   6270  C  CA  . TRP B 1 317 ? 163.952 160.085 129.291 1.00 60.15  ? 317 TRP B CA  1 
ATOM   6271  C  C   . TRP B 1 317 ? 164.105 161.576 129.556 1.00 60.15  ? 317 TRP B C   1 
ATOM   6272  O  O   . TRP B 1 317 ? 163.656 162.105 130.577 1.00 60.15  ? 317 TRP B O   1 
ATOM   6273  C  CB  . TRP B 1 317 ? 162.896 159.849 128.205 1.00 60.15  ? 317 TRP B CB  1 
ATOM   6274  C  CG  . TRP B 1 317 ? 162.834 158.437 127.731 1.00 60.15  ? 317 TRP B CG  1 
ATOM   6275  C  CD1 . TRP B 1 317 ? 163.572 157.873 126.736 1.00 60.15  ? 317 TRP B CD1 1 
ATOM   6276  C  CD2 . TRP B 1 317 ? 161.976 157.407 128.227 1.00 60.15  ? 317 TRP B CD2 1 
ATOM   6277  N  NE1 . TRP B 1 317 ? 163.232 156.552 126.584 1.00 60.15  ? 317 TRP B NE1 1 
ATOM   6278  C  CE2 . TRP B 1 317 ? 162.252 156.242 127.489 1.00 60.15  ? 317 TRP B CE2 1 
ATOM   6279  C  CE3 . TRP B 1 317 ? 161.001 157.356 129.225 1.00 60.15  ? 317 TRP B CE3 1 
ATOM   6280  C  CZ2 . TRP B 1 317 ? 161.591 155.042 127.717 1.00 60.15  ? 317 TRP B CZ2 1 
ATOM   6281  C  CZ3 . TRP B 1 317 ? 160.348 156.166 129.449 1.00 60.15  ? 317 TRP B CZ3 1 
ATOM   6282  C  CH2 . TRP B 1 317 ? 160.643 155.025 128.699 1.00 60.15  ? 317 TRP B CH2 1 
ATOM   6283  N  N   . LYS B 1 318 ? 164.738 162.259 128.592 1.00 64.29  ? 318 LYS B N   1 
ATOM   6284  C  CA  . LYS B 1 318 ? 165.139 163.663 128.703 1.00 64.29  ? 318 LYS B CA  1 
ATOM   6285  C  C   . LYS B 1 318 ? 164.857 164.340 127.358 1.00 64.29  ? 318 LYS B C   1 
ATOM   6286  O  O   . LYS B 1 318 ? 165.374 163.953 126.308 1.00 64.29  ? 318 LYS B O   1 
ATOM   6287  C  CB  . LYS B 1 318 ? 166.608 163.785 129.108 1.00 64.29  ? 318 LYS B CB  1 
ATOM   6288  C  CG  . LYS B 1 318 ? 167.130 165.198 129.265 1.00 64.29  ? 318 LYS B CG  1 
ATOM   6289  C  CD  . LYS B 1 318 ? 167.867 165.645 128.018 1.00 64.29  ? 318 LYS B CD  1 
ATOM   6290  C  CE  . LYS B 1 318 ? 168.503 167.006 128.209 1.00 64.29  ? 318 LYS B CE  1 
ATOM   6291  N  NZ  . LYS B 1 318 ? 169.220 167.452 126.985 1.00 64.29  ? 318 LYS B NZ  1 
ATOM   6292  N  N   . CYS B 1 319 ? 164.027 165.378 127.398 1.00 74.20  ? 319 CYS B N   1 
ATOM   6293  C  CA  . CYS B 1 319 ? 163.625 166.076 126.188 1.00 74.20  ? 319 CYS B CA  1 
ATOM   6294  C  C   . CYS B 1 319 ? 163.989 167.556 126.255 1.00 74.20  ? 319 CYS B C   1 
ATOM   6295  O  O   . CYS B 1 319 ? 164.313 168.102 127.313 1.00 74.20  ? 319 CYS B O   1 
ATOM   6296  C  CB  . CYS B 1 319 ? 162.123 165.936 125.958 1.00 74.20  ? 319 CYS B CB  1 
ATOM   6297  S  SG  . CYS B 1 319 ? 161.528 166.769 124.474 1.00 74.20  ? 319 CYS B SG  1 
ATOM   6298  N  N   . ASN B 1 320 ? 163.912 168.207 125.097 1.00 88.67  ? 320 ASN B N   1 
ATOM   6299  C  CA  . ASN B 1 320 ? 164.198 169.628 124.978 1.00 88.67  ? 320 ASN B CA  1 
ATOM   6300  C  C   . ASN B 1 320 ? 163.598 170.130 123.672 1.00 88.67  ? 320 ASN B C   1 
ATOM   6301  O  O   . ASN B 1 320 ? 163.424 169.356 122.727 1.00 88.67  ? 320 ASN B O   1 
ATOM   6302  C  CB  . ASN B 1 320 ? 165.707 169.897 125.022 1.00 88.67  ? 320 ASN B CB  1 
ATOM   6303  C  CG  . ASN B 1 320 ? 166.036 171.370 125.149 1.00 88.67  ? 320 ASN B CG  1 
ATOM   6304  O  OD1 . ASN B 1 320 ? 165.146 172.220 125.173 1.00 88.67  ? 320 ASN B OD1 1 
ATOM   6305  N  ND2 . ASN B 1 320 ? 167.323 171.679 125.236 1.00 88.67  ? 320 ASN B ND2 1 
ATOM   6306  N  N   . ASN B 1 321 ? 163.281 171.426 123.626 1.00 95.51  ? 321 ASN B N   1 
ATOM   6307  C  CA  . ASN B 1 321 ? 162.632 171.985 122.443 1.00 95.51  ? 321 ASN B CA  1 
ATOM   6308  C  C   . ASN B 1 321 ? 163.579 172.038 121.251 1.00 95.51  ? 321 ASN B C   1 
ATOM   6309  O  O   . ASN B 1 321 ? 163.138 172.159 120.102 1.00 95.51  ? 321 ASN B O   1 
ATOM   6310  C  CB  . ASN B 1 321 ? 162.086 173.382 122.749 1.00 95.51  ? 321 ASN B CB  1 
ATOM   6311  C  CG  . ASN B 1 321 ? 160.866 173.347 123.648 1.00 95.51  ? 321 ASN B CG  1 
ATOM   6312  O  OD1 . ASN B 1 321 ? 159.983 172.505 123.482 1.00 95.51  ? 321 ASN B OD1 1 
ATOM   6313  N  ND2 . ASN B 1 321 ? 160.809 174.265 124.606 1.00 95.51  ? 321 ASN B ND2 1 
ATOM   6314  N  N   . ALA B 1 322 ? 164.883 171.947 121.500 1.00 94.16  ? 322 ALA B N   1 
ATOM   6315  C  CA  . ALA B 1 322 ? 165.885 172.068 120.441 1.00 94.16  ? 322 ALA B CA  1 
ATOM   6316  C  C   . ALA B 1 322 ? 166.543 170.740 120.100 1.00 94.16  ? 322 ALA B C   1 
ATOM   6317  O  O   . ALA B 1 322 ? 167.759 170.681 119.899 1.00 94.16  ? 322 ALA B O   1 
ATOM   6318  C  CB  . ALA B 1 322 ? 166.931 173.101 120.844 1.00 94.16  ? 322 ALA B CB  1 
ATOM   6319  N  N   . THR B 1 323 ? 165.770 169.657 120.022 1.00 91.09  ? 323 THR B N   1 
ATOM   6320  C  CA  . THR B 1 323 ? 166.330 168.359 119.664 1.00 91.09  ? 323 THR B CA  1 
ATOM   6321  C  C   . THR B 1 323 ? 165.255 167.415 119.141 1.00 91.09  ? 323 THR B C   1 
ATOM   6322  O  O   . THR B 1 323 ? 165.568 166.455 118.430 1.00 91.09  ? 323 THR B O   1 
ATOM   6323  C  CB  . THR B 1 323 ? 167.047 167.731 120.864 1.00 91.09  ? 323 THR B CB  1 
ATOM   6324  O  OG1 . THR B 1 323 ? 167.731 166.543 120.448 1.00 91.09  ? 323 THR B OG1 1 
ATOM   6325  C  CG2 . THR B 1 323 ? 166.057 167.382 121.965 1.00 91.09  ? 323 THR B CG2 1 
ATOM   6326  N  N   . VAL B 1 324 ? 163.993 167.683 119.497 1.00 90.33  ? 324 VAL B N   1 
ATOM   6327  C  CA  . VAL B 1 324 ? 162.809 166.888 119.155 1.00 90.33  ? 324 VAL B CA  1 
ATOM   6328  C  C   . VAL B 1 324 ? 163.092 165.392 119.298 1.00 90.33  ? 324 VAL B C   1 
ATOM   6329  O  O   . VAL B 1 324 ? 162.489 164.556 118.614 1.00 90.33  ? 324 VAL B O   1 
ATOM   6330  C  CB  . VAL B 1 324 ? 162.278 167.254 117.747 1.00 90.33  ? 324 VAL B CB  1 
ATOM   6331  C  CG1 . VAL B 1 324 ? 163.176 166.737 116.615 1.00 90.33  ? 324 VAL B CG1 1 
ATOM   6332  C  CG2 . VAL B 1 324 ? 160.819 166.817 117.565 1.00 90.33  ? 324 VAL B CG2 1 
ATOM   6333  N  N   . ASP B 1 325 ? 163.984 165.041 120.217 1.00 85.02  ? 325 ASP B N   1 
ATOM   6334  C  CA  . ASP B 1 325 ? 164.351 163.660 120.475 1.00 85.02  ? 325 ASP B CA  1 
ATOM   6335  C  C   . ASP B 1 325 ? 164.011 163.301 121.922 1.00 85.02  ? 325 ASP B C   1 
ATOM   6336  O  O   . ASP B 1 325 ? 163.266 164.019 122.598 1.00 85.02  ? 325 ASP B O   1 
ATOM   6337  C  CB  . ASP B 1 325 ? 165.838 163.455 120.165 1.00 85.02  ? 325 ASP B CB  1 
ATOM   6338  C  CG  . ASP B 1 325 ? 166.135 163.499 118.685 1.00 85.02  ? 325 ASP B CG  1 
ATOM   6339  O  OD1 . ASP B 1 325 ? 165.243 163.136 117.891 1.00 85.02  ? 325 ASP B OD1 1 
ATOM   6340  O  OD2 . ASP B 1 325 ? 167.261 163.894 118.316 1.00 85.02  ? 325 ASP B OD2 1 
ATOM   6341  N  N   . TRP B 1 326 ? 164.558 162.188 122.403 1.00 72.80  ? 326 TRP B N   1 
ATOM   6342  C  CA  . TRP B 1 326 ? 164.393 161.775 123.789 1.00 72.80  ? 326 TRP B CA  1 
ATOM   6343  C  C   . TRP B 1 326 ? 165.655 161.082 124.278 1.00 72.80  ? 326 TRP B C   1 
ATOM   6344  O  O   . TRP B 1 326 ? 165.694 159.851 124.374 1.00 72.80  ? 326 TRP B O   1 
ATOM   6345  C  CB  . TRP B 1 326 ? 163.181 160.854 123.938 1.00 72.80  ? 326 TRP B CB  1 
ATOM   6346  C  CG  . TRP B 1 326 ? 161.868 161.557 123.813 1.00 72.80  ? 326 TRP B CG  1 
ATOM   6347  C  CD1 . TRP B 1 326 ? 161.113 161.687 122.688 1.00 72.80  ? 326 TRP B CD1 1 
ATOM   6348  C  CD2 . TRP B 1 326 ? 161.144 162.214 124.861 1.00 72.80  ? 326 TRP B CD2 1 
ATOM   6349  N  NE1 . TRP B 1 326 ? 159.967 162.391 122.966 1.00 72.80  ? 326 TRP B NE1 1 
ATOM   6350  C  CE2 . TRP B 1 326 ? 159.962 162.725 124.294 1.00 72.80  ? 326 TRP B CE2 1 
ATOM   6351  C  CE3 . TRP B 1 326 ? 161.382 162.420 126.223 1.00 72.80  ? 326 TRP B CE3 1 
ATOM   6352  C  CZ2 . TRP B 1 326 ? 159.021 163.431 125.040 1.00 72.80  ? 326 TRP B CZ2 1 
ATOM   6353  C  CZ3 . TRP B 1 326 ? 160.447 163.118 126.961 1.00 72.80  ? 326 TRP B CZ3 1 
ATOM   6354  C  CH2 . TRP B 1 326 ? 159.283 163.618 126.368 1.00 72.80  ? 326 TRP B CH2 1 
ATOM   6355  N  N   . GLU B 1 327 ? 166.692 161.860 124.578 1.00 69.82  ? 327 GLU B N   1 
ATOM   6356  C  CA  . GLU B 1 327 ? 167.946 161.298 125.064 1.00 69.82  ? 327 GLU B CA  1 
ATOM   6357  C  C   . GLU B 1 327 ? 167.720 160.503 126.340 1.00 69.82  ? 327 GLU B C   1 
ATOM   6358  O  O   . GLU B 1 327 ? 167.689 161.066 127.437 1.00 69.82  ? 327 GLU B O   1 
ATOM   6359  C  CB  . GLU B 1 327 ? 168.967 162.412 125.306 1.00 69.82  ? 327 GLU B CB  1 
ATOM   6360  C  CG  . GLU B 1 327 ? 169.494 163.076 124.043 1.00 69.82  ? 327 GLU B CG  1 
ATOM   6361  C  CD  . GLU B 1 327 ? 168.584 164.172 123.525 1.00 69.82  ? 327 GLU B CD  1 
ATOM   6362  O  OE1 . GLU B 1 327 ? 167.556 164.455 124.176 1.00 69.82  ? 327 GLU B OE1 1 
ATOM   6363  O  OE2 . GLU B 1 327 ? 168.900 164.757 122.468 1.00 69.82  ? 327 GLU B OE2 1 
ATOM   6364  N  N   . TRP B 1 328 ? 167.546 159.194 126.180 1.00 65.27  ? 328 TRP B N   1 
ATOM   6365  C  CA  . TRP B 1 328 ? 167.431 158.274 127.303 1.00 65.27  ? 328 TRP B CA  1 
ATOM   6366  C  C   . TRP B 1 328 ? 168.517 158.518 128.347 1.00 65.27  ? 328 TRP B C   1 
ATOM   6367  O  O   . TRP B 1 328 ? 169.684 158.749 128.022 1.00 65.27  ? 328 TRP B O   1 
ATOM   6368  C  CB  . TRP B 1 328 ? 167.512 156.836 126.797 1.00 65.27  ? 328 TRP B CB  1 
ATOM   6369  C  CG  . TRP B 1 328 ? 167.665 155.830 127.876 1.00 65.27  ? 328 TRP B CG  1 
ATOM   6370  C  CD1 . TRP B 1 328 ? 166.751 155.498 128.831 1.00 65.27  ? 328 TRP B CD1 1 
ATOM   6371  C  CD2 . TRP B 1 328 ? 168.824 155.033 128.132 1.00 65.27  ? 328 TRP B CD2 1 
ATOM   6372  N  NE1 . TRP B 1 328 ? 167.268 154.532 129.661 1.00 65.27  ? 328 TRP B NE1 1 
ATOM   6373  C  CE2 . TRP B 1 328 ? 168.541 154.231 129.251 1.00 65.27  ? 328 TRP B CE2 1 
ATOM   6374  C  CE3 . TRP B 1 328 ? 170.075 154.916 127.517 1.00 65.27  ? 328 TRP B CE3 1 
ATOM   6375  C  CZ2 . TRP B 1 328 ? 169.464 153.328 129.772 1.00 65.27  ? 328 TRP B CZ2 1 
ATOM   6376  C  CZ3 . TRP B 1 328 ? 170.985 154.018 128.034 1.00 65.27  ? 328 TRP B CZ3 1 
ATOM   6377  C  CH2 . TRP B 1 328 ? 170.676 153.236 129.149 1.00 65.27  ? 328 TRP B CH2 1 
ATOM   6378  N  N   . CYS B 1 329 ? 168.119 158.462 129.614 1.00 58.85  ? 329 CYS B N   1 
ATOM   6379  C  CA  . CYS B 1 329 ? 169.020 158.629 130.748 1.00 58.85  ? 329 CYS B CA  1 
ATOM   6380  C  C   . CYS B 1 329 ? 169.065 157.344 131.570 1.00 58.85  ? 329 CYS B C   1 
ATOM   6381  O  O   . CYS B 1 329 ? 168.328 156.390 131.315 1.00 58.85  ? 329 CYS B O   1 
ATOM   6382  C  CB  . CYS B 1 329 ? 168.597 159.818 131.616 1.00 58.85  ? 329 CYS B CB  1 
ATOM   6383  S  SG  . CYS B 1 329 ? 168.790 161.424 130.825 1.00 58.85  ? 329 CYS B SG  1 
ATOM   6384  N  N   . ALA B 1 330 ? 169.936 157.337 132.575 1.00 57.18  ? 330 ALA B N   1 
ATOM   6385  C  CA  . ALA B 1 330 ? 170.167 156.133 133.359 1.00 57.18  ? 330 ALA B CA  1 
ATOM   6386  C  C   . ALA B 1 330 ? 168.908 155.747 134.132 1.00 57.18  ? 330 ALA B C   1 
ATOM   6387  O  O   . ALA B 1 330 ? 168.188 156.620 134.624 1.00 57.18  ? 330 ALA B O   1 
ATOM   6388  C  CB  . ALA B 1 330 ? 171.330 156.342 134.325 1.00 57.18  ? 330 ALA B CB  1 
ATOM   6389  N  N   . PRO B 1 331 ? 168.617 154.454 134.257 1.00 52.79  ? 331 PRO B N   1 
ATOM   6390  C  CA  . PRO B 1 331 ? 167.385 154.038 134.933 1.00 52.79  ? 331 PRO B CA  1 
ATOM   6391  C  C   . PRO B 1 331 ? 167.518 154.098 136.445 1.00 52.79  ? 331 PRO B C   1 
ATOM   6392  O  O   . PRO B 1 331 ? 168.615 154.022 137.003 1.00 52.79  ? 331 PRO B O   1 
ATOM   6393  C  CB  . PRO B 1 331 ? 167.195 152.597 134.453 1.00 52.79  ? 331 PRO B CB  1 
ATOM   6394  C  CG  . PRO B 1 331 ? 168.578 152.124 134.194 1.00 52.79  ? 331 PRO B CG  1 
ATOM   6395  C  CD  . PRO B 1 331 ? 169.341 153.311 133.677 1.00 52.79  ? 331 PRO B CD  1 
ATOM   6396  N  N   . LEU B 1 332 ? 166.372 154.229 137.107 1.00 48.89  ? 332 LEU B N   1 
ATOM   6397  C  CA  . LEU B 1 332 ? 166.348 154.282 138.557 1.00 48.89  ? 332 LEU B CA  1 
ATOM   6398  C  C   . LEU B 1 332 ? 166.783 152.940 139.145 1.00 48.89  ? 332 LEU B C   1 
ATOM   6399  O  O   . LEU B 1 332 ? 166.762 151.917 138.459 1.00 48.89  ? 332 LEU B O   1 
ATOM   6400  C  CB  . LEU B 1 332 ? 164.949 154.631 139.056 1.00 48.89  ? 332 LEU B CB  1 
ATOM   6401  C  CG  . LEU B 1 332 ? 164.476 156.086 138.997 1.00 48.89  ? 332 LEU B CG  1 
ATOM   6402  C  CD1 . LEU B 1 332 ? 164.162 156.524 137.576 1.00 48.89  ? 332 LEU B CD1 1 
ATOM   6403  C  CD2 . LEU B 1 332 ? 163.264 156.274 139.890 1.00 48.89  ? 332 LEU B CD2 1 
ATOM   6404  N  N   . PRO B 1 333 ? 167.214 152.923 140.405 1.00 48.00  ? 333 PRO B N   1 
ATOM   6405  C  CA  . PRO B 1 333 ? 167.457 151.651 141.095 1.00 48.00  ? 333 PRO B CA  1 
ATOM   6406  C  C   . PRO B 1 333 ? 166.262 151.091 141.854 1.00 48.00  ? 333 PRO B C   1 
ATOM   6407  O  O   . PRO B 1 333 ? 166.449 150.172 142.659 1.00 48.00  ? 333 PRO B O   1 
ATOM   6408  C  CB  . PRO B 1 333 ? 168.586 152.016 142.069 1.00 48.00  ? 333 PRO B CB  1 
ATOM   6409  C  CG  . PRO B 1 333 ? 168.379 153.444 142.355 1.00 48.00  ? 333 PRO B CG  1 
ATOM   6410  C  CD  . PRO B 1 333 ? 167.853 154.056 141.095 1.00 48.00  ? 333 PRO B CD  1 
ATOM   6411  N  N   . ARG B 1 334 ? 165.051 151.601 141.624 1.00 54.80  ? 334 ARG B N   1 
ATOM   6412  C  CA  . ARG B 1 334 ? 163.868 151.165 142.352 1.00 54.80  ? 334 ARG B CA  1 
ATOM   6413  C  C   . ARG B 1 334 ? 162.656 151.194 141.431 1.00 54.80  ? 334 ARG B C   1 
ATOM   6414  O  O   . ARG B 1 334 ? 162.582 152.005 140.506 1.00 54.80  ? 334 ARG B O   1 
ATOM   6415  C  CB  . ARG B 1 334 ? 163.612 152.048 143.580 1.00 54.80  ? 334 ARG B CB  1 
ATOM   6416  C  CG  . ARG B 1 334 ? 164.666 151.932 144.667 1.00 54.80  ? 334 ARG B CG  1 
ATOM   6417  C  CD  . ARG B 1 334 ? 164.358 152.842 145.837 1.00 54.80  ? 334 ARG B CD  1 
ATOM   6418  N  NE  . ARG B 1 334 ? 165.418 152.817 146.838 1.00 54.80  ? 334 ARG B NE  1 
ATOM   6419  C  CZ  . ARG B 1 334 ? 165.460 151.967 147.857 1.00 54.80  ? 334 ARG B CZ  1 
ATOM   6420  N  NH1 . ARG B 1 334 ? 164.497 151.071 148.013 1.00 54.80  ? 334 ARG B NH1 1 
ATOM   6421  N  NH2 . ARG B 1 334 ? 166.462 152.017 148.722 1.00 54.80  ? 334 ARG B NH2 1 
ATOM   6422  N  N   . ASP B 1 335 ? 161.699 150.303 141.699 1.00 62.72  ? 335 ASP B N   1 
ATOM   6423  C  CA  . ASP B 1 335 ? 160.471 150.198 140.906 1.00 62.72  ? 335 ASP B CA  1 
ATOM   6424  C  C   . ASP B 1 335 ? 159.296 150.760 141.700 1.00 62.72  ? 335 ASP B C   1 
ATOM   6425  O  O   . ASP B 1 335 ? 158.484 150.032 142.268 1.00 62.72  ? 335 ASP B O   1 
ATOM   6426  C  CB  . ASP B 1 335 ? 160.217 148.754 140.492 1.00 62.72  ? 335 ASP B CB  1 
ATOM   6427  C  CG  . ASP B 1 335 ? 161.088 148.324 139.348 1.00 62.72  ? 335 ASP B CG  1 
ATOM   6428  O  OD1 . ASP B 1 335 ? 161.438 149.200 138.538 1.00 62.72  ? 335 ASP B OD1 1 
ATOM   6429  O  OD2 . ASP B 1 335 ? 161.412 147.123 139.249 1.00 62.72  ? 335 ASP B OD2 1 
ATOM   6430  N  N   . ARG B 1 336 ? 159.199 152.084 141.715 1.00 57.65  ? 336 ARG B N   1 
ATOM   6431  C  CA  . ARG B 1 336 ? 158.140 152.781 142.421 1.00 57.65  ? 336 ARG B CA  1 
ATOM   6432  C  C   . ARG B 1 336 ? 157.347 153.635 141.445 1.00 57.65  ? 336 ARG B C   1 
ATOM   6433  O  O   . ARG B 1 336 ? 157.899 154.188 140.490 1.00 57.65  ? 336 ARG B O   1 
ATOM   6434  C  CB  . ARG B 1 336 ? 158.705 153.667 143.530 1.00 57.65  ? 336 ARG B CB  1 
ATOM   6435  C  CG  . ARG B 1 336 ? 159.399 152.907 144.635 1.00 57.65  ? 336 ARG B CG  1 
ATOM   6436  C  CD  . ARG B 1 336 ? 159.994 153.868 145.634 1.00 57.65  ? 336 ARG B CD  1 
ATOM   6437  N  NE  . ARG B 1 336 ? 161.046 154.671 145.023 1.00 57.65  ? 336 ARG B NE  1 
ATOM   6438  C  CZ  . ARG B 1 336 ? 161.655 155.686 145.621 1.00 57.65  ? 336 ARG B CZ  1 
ATOM   6439  N  NH1 . ARG B 1 336 ? 161.322 156.025 146.857 1.00 57.65  ? 336 ARG B NH1 1 
ATOM   6440  N  NH2 . ARG B 1 336 ? 162.602 156.359 144.986 1.00 57.65  ? 336 ARG B NH2 1 
ATOM   6441  N  N   . LEU B 1 337 ? 156.046 153.737 141.691 1.00 60.06  ? 337 LEU B N   1 
ATOM   6442  C  CA  . LEU B 1 337 ? 155.184 154.627 140.932 1.00 60.06  ? 337 LEU B CA  1 
ATOM   6443  C  C   . LEU B 1 337 ? 154.480 155.576 141.890 1.00 60.06  ? 337 LEU B C   1 
ATOM   6444  O  O   . LEU B 1 337 ? 154.343 155.297 143.084 1.00 60.06  ? 337 LEU B O   1 
ATOM   6445  C  CB  . LEU B 1 337 ? 154.171 153.852 140.072 1.00 60.06  ? 337 LEU B CB  1 
ATOM   6446  C  CG  . LEU B 1 337 ? 153.003 153.093 140.697 1.00 60.06  ? 337 LEU B CG  1 
ATOM   6447  C  CD1 . LEU B 1 337 ? 151.955 152.830 139.632 1.00 60.06  ? 337 LEU B CD1 1 
ATOM   6448  C  CD2 . LEU B 1 337 ? 153.470 151.783 141.300 1.00 60.06  ? 337 LEU B CD2 1 
ATOM   6449  N  N   . GLN B 1 338 ? 154.047 156.714 141.346 1.00 62.39  ? 338 GLN B N   1 
ATOM   6450  C  CA  . GLN B 1 338 ? 153.526 157.831 142.137 1.00 62.39  ? 338 GLN B CA  1 
ATOM   6451  C  C   . GLN B 1 338 ? 154.563 158.337 143.136 1.00 62.39  ? 338 GLN B C   1 
ATOM   6452  O  O   . GLN B 1 338 ? 154.231 158.742 144.251 1.00 62.39  ? 338 GLN B O   1 
ATOM   6453  C  CB  . GLN B 1 338 ? 152.223 157.465 142.849 1.00 62.39  ? 338 GLN B CB  1 
ATOM   6454  C  CG  . GLN B 1 338 ? 151.039 157.293 141.923 1.00 62.39  ? 338 GLN B CG  1 
ATOM   6455  C  CD  . GLN B 1 338 ? 149.766 156.966 142.672 1.00 62.39  ? 338 GLN B CD  1 
ATOM   6456  O  OE1 . GLN B 1 338 ? 149.779 156.775 143.887 1.00 62.39  ? 338 GLN B OE1 1 
ATOM   6457  N  NE2 . GLN B 1 338 ? 148.653 156.913 141.951 1.00 62.39  ? 338 GLN B NE2 1 
ATOM   6458  N  N   . HIS B 1 339 ? 155.830 158.317 142.737 1.00 54.24  ? 339 HIS B N   1 
ATOM   6459  C  CA  . HIS B 1 339 ? 156.893 158.904 143.536 1.00 54.24  ? 339 HIS B CA  1 
ATOM   6460  C  C   . HIS B 1 339 ? 156.953 160.405 143.253 1.00 54.24  ? 339 HIS B C   1 
ATOM   6461  O  O   . HIS B 1 339 ? 156.102 160.958 142.553 1.00 54.24  ? 339 HIS B O   1 
ATOM   6462  C  CB  . HIS B 1 339 ? 158.212 158.183 143.267 1.00 54.24  ? 339 HIS B CB  1 
ATOM   6463  C  CG  . HIS B 1 339 ? 158.667 158.258 141.844 1.00 54.24  ? 339 HIS B CG  1 
ATOM   6464  N  ND1 . HIS B 1 339 ? 158.147 157.451 140.856 1.00 54.24  ? 339 HIS B ND1 1 
ATOM   6465  C  CD2 . HIS B 1 339 ? 159.603 159.030 141.245 1.00 54.24  ? 339 HIS B CD2 1 
ATOM   6466  C  CE1 . HIS B 1 339 ? 158.735 157.732 139.707 1.00 54.24  ? 339 HIS B CE1 1 
ATOM   6467  N  NE2 . HIS B 1 339 ? 159.624 158.685 139.916 1.00 54.24  ? 339 HIS B NE2 1 
ATOM   6468  N  N   . THR B 1 340 ? 157.956 161.089 143.799 1.00 54.42  ? 340 THR B N   1 
ATOM   6469  C  CA  . THR B 1 340 ? 158.026 162.548 143.743 1.00 54.42  ? 340 THR B CA  1 
ATOM   6470  C  C   . THR B 1 340 ? 159.363 163.008 143.174 1.00 54.42  ? 340 THR B C   1 
ATOM   6471  O  O   . THR B 1 340 ? 160.413 162.883 143.805 1.00 54.42  ? 340 THR B O   1 
ATOM   6472  C  CB  . THR B 1 340 ? 157.800 163.143 145.129 1.00 54.42  ? 340 THR B CB  1 
ATOM   6473  O  OG1 . THR B 1 340 ? 156.509 162.754 145.614 1.00 54.42  ? 340 THR B OG1 1 
ATOM   6474  C  CG2 . THR B 1 340 ? 157.883 164.659 145.081 1.00 54.42  ? 340 THR B CG2 1 
ATOM   6475  N  N   . LEU B 1 341 ? 159.336 163.570 141.967 1.00 52.83  ? 341 LEU B N   1 
ATOM   6476  C  CA  . LEU B 1 341 ? 160.545 164.127 141.371 1.00 52.83  ? 341 LEU B CA  1 
ATOM   6477  C  C   . LEU B 1 341 ? 160.667 165.613 141.678 1.00 52.83  ? 341 LEU B C   1 
ATOM   6478  O  O   . LEU B 1 341 ? 159.749 166.392 141.405 1.00 52.83  ? 341 LEU B O   1 
ATOM   6479  C  CB  . LEU B 1 341 ? 160.545 163.898 139.859 1.00 52.83  ? 341 LEU B CB  1 
ATOM   6480  C  CG  . LEU B 1 341 ? 160.735 162.475 139.339 1.00 52.83  ? 341 LEU B CG  1 
ATOM   6481  C  CD1 . LEU B 1 341 ? 160.550 162.453 137.841 1.00 52.83  ? 341 LEU B CD1 1 
ATOM   6482  C  CD2 . LEU B 1 341 ? 162.110 161.956 139.703 1.00 52.83  ? 341 LEU B CD2 1 
ATOM   6483  N  N   . VAL B 1 342 ? 161.806 166.001 142.246 1.00 53.95  ? 342 VAL B N   1 
ATOM   6484  C  CA  . VAL B 1 342 ? 162.105 167.390 142.577 1.00 53.95  ? 342 VAL B CA  1 
ATOM   6485  C  C   . VAL B 1 342 ? 163.403 167.742 141.860 1.00 53.95  ? 342 VAL B C   1 
ATOM   6486  O  O   . VAL B 1 342 ? 164.190 166.847 141.534 1.00 53.95  ? 342 VAL B O   1 
ATOM   6487  C  CB  . VAL B 1 342 ? 162.225 167.602 144.097 1.00 53.95  ? 342 VAL B CB  1 
ATOM   6488  C  CG1 . VAL B 1 342 ? 162.488 169.056 144.439 1.00 53.95  ? 342 VAL B CG1 1 
ATOM   6489  C  CG2 . VAL B 1 342 ? 160.968 167.116 144.797 1.00 53.95  ? 342 VAL B CG2 1 
ATOM   6490  N  N   . SER B 1 343 ? 163.620 169.026 141.585 1.00 59.46  ? 343 SER B N   1 
ATOM   6491  C  CA  . SER B 1 343 ? 164.767 169.455 140.794 1.00 59.46  ? 343 SER B CA  1 
ATOM   6492  C  C   . SER B 1 343 ? 165.462 170.642 141.440 1.00 59.46  ? 343 SER B C   1 
ATOM   6493  O  O   . SER B 1 343 ? 165.984 170.531 142.554 1.00 59.46  ? 343 SER B O   1 
ATOM   6494  C  CB  . SER B 1 343 ? 164.340 169.822 139.374 1.00 59.46  ? 343 SER B CB  1 
ATOM   6495  O  OG  . SER B 1 343 ? 165.438 170.325 138.638 1.00 59.46  ? 343 SER B OG  1 
ATOM   6496  N  N   . VAL B 1 344 ? 165.477 171.763 140.721 1.00 71.32  ? 344 VAL B N   1 
ATOM   6497  C  CA  . VAL B 1 344 ? 166.167 173.003 141.085 1.00 71.32  ? 344 VAL B CA  1 
ATOM   6498  C  C   . VAL B 1 344 ? 167.672 172.765 141.148 1.00 71.32  ? 344 VAL B C   1 
ATOM   6499  O  O   . VAL B 1 344 ? 168.154 172.014 142.009 1.00 71.32  ? 344 VAL B O   1 
ATOM   6500  C  CB  . VAL B 1 344 ? 165.636 173.586 142.404 1.00 71.32  ? 344 VAL B CB  1 
ATOM   6501  C  CG1 . VAL B 1 344 ? 166.457 174.799 142.813 1.00 71.32  ? 344 VAL B CG1 1 
ATOM   6502  C  CG2 . VAL B 1 344 ? 164.169 173.958 142.259 1.00 71.32  ? 344 VAL B CG2 1 
ATOM   6503  N  N   . PRO B 1 345 ? 168.448 173.391 140.267 1.00 72.98  ? 345 PRO B N   1 
ATOM   6504  C  CA  . PRO B 1 345 ? 169.887 173.109 140.213 1.00 72.98  ? 345 PRO B CA  1 
ATOM   6505  C  C   . PRO B 1 345 ? 170.674 173.787 141.320 1.00 72.98  ? 345 PRO B C   1 
ATOM   6506  O  O   . PRO B 1 345 ? 171.531 174.633 141.048 1.00 72.98  ? 345 PRO B O   1 
ATOM   6507  C  CB  . PRO B 1 345 ? 170.291 173.647 138.836 1.00 72.98  ? 345 PRO B CB  1 
ATOM   6508  C  CG  . PRO B 1 345 ? 169.319 174.744 138.578 1.00 72.98  ? 345 PRO B CG  1 
ATOM   6509  C  CD  . PRO B 1 345 ? 168.021 174.318 139.206 1.00 72.98  ? 345 PRO B CD  1 
ATOM   6510  N  N   . GLY B 1 346 ? 170.396 173.428 142.569 1.00 75.58  ? 346 GLY B N   1 
ATOM   6511  C  CA  . GLY B 1 346 ? 171.196 173.920 143.673 1.00 75.58  ? 346 GLY B CA  1 
ATOM   6512  C  C   . GLY B 1 346 ? 172.573 173.293 143.674 1.00 75.58  ? 346 GLY B C   1 
ATOM   6513  O  O   . GLY B 1 346 ? 173.523 173.847 144.236 1.00 75.58  ? 346 GLY B O   1 
ATOM   6514  N  N   . LYS B 1 347 ? 172.687 172.129 143.033 1.00 72.28  ? 347 LYS B N   1 
ATOM   6515  C  CA  . LYS B 1 347 ? 173.938 171.389 142.934 1.00 72.28  ? 347 LYS B CA  1 
ATOM   6516  C  C   . LYS B 1 347 ? 173.797 170.303 141.863 1.00 72.28  ? 347 LYS B C   1 
ATOM   6517  O  O   . LYS B 1 347 ? 174.518 169.310 141.842 1.00 72.28  ? 347 LYS B O   1 
ATOM   6518  C  CB  . LYS B 1 347 ? 174.331 170.828 144.301 1.00 72.28  ? 347 LYS B CB  1 
ATOM   6519  C  CG  . LYS B 1 347 ? 173.275 169.958 144.969 1.00 72.28  ? 347 LYS B CG  1 
ATOM   6520  C  CD  . LYS B 1 347 ? 173.483 168.482 144.700 1.00 72.28  ? 347 LYS B CD  1 
ATOM   6521  C  CE  . LYS B 1 347 ? 172.498 167.645 145.492 1.00 72.28  ? 347 LYS B CE  1 
ATOM   6522  N  NZ  . LYS B 1 347 ? 172.678 166.191 145.242 1.00 72.28  ? 347 LYS B NZ  1 
ATOM   6523  N  N   . ASP B 1 348 ? 172.851 170.512 140.952 1.00 72.58  ? 348 ASP B N   1 
ATOM   6524  C  CA  . ASP B 1 348 ? 172.595 169.625 139.816 1.00 72.58  ? 348 ASP B CA  1 
ATOM   6525  C  C   . ASP B 1 348 ? 172.251 168.213 140.284 1.00 72.58  ? 348 ASP B C   1 
ATOM   6526  O  O   . ASP B 1 348 ? 173.107 167.339 140.412 1.00 72.58  ? 348 ASP B O   1 
ATOM   6527  C  CB  . ASP B 1 348 ? 173.782 169.609 138.854 1.00 72.58  ? 348 ASP B CB  1 
ATOM   6528  C  CG  . ASP B 1 348 ? 173.956 170.923 138.126 1.00 72.58  ? 348 ASP B CG  1 
ATOM   6529  O  OD1 . ASP B 1 348 ? 172.946 171.629 137.926 1.00 72.58  ? 348 ASP B OD1 1 
ATOM   6530  O  OD2 . ASP B 1 348 ? 175.101 171.249 137.750 1.00 72.58  ? 348 ASP B OD2 1 
ATOM   6531  N  N   . ALA B 1 349 ? 170.959 168.000 140.529 1.00 58.66  ? 349 ALA B N   1 
ATOM   6532  C  CA  . ALA B 1 349 ? 170.456 166.707 140.962 1.00 58.66  ? 349 ALA B CA  1 
ATOM   6533  C  C   . ALA B 1 349 ? 168.942 166.661 140.832 1.00 58.66  ? 349 ALA B C   1 
ATOM   6534  O  O   . ALA B 1 349 ? 168.248 167.648 141.086 1.00 58.66  ? 349 ALA B O   1 
ATOM   6535  C  CB  . ALA B 1 349 ? 170.854 166.402 142.410 1.00 58.66  ? 349 ALA B CB  1 
ATOM   6536  N  N   . ILE B 1 350 ? 168.439 165.496 140.433 1.00 52.84  ? 350 ILE B N   1 
ATOM   6537  C  CA  . ILE B 1 350 ? 167.009 165.218 140.364 1.00 52.84  ? 350 ILE B CA  1 
ATOM   6538  C  C   . ILE B 1 350 ? 166.697 164.246 141.492 1.00 52.84  ? 350 ILE B C   1 
ATOM   6539  O  O   . ILE B 1 350 ? 167.264 163.149 141.540 1.00 52.84  ? 350 ILE B O   1 
ATOM   6540  C  CB  . ILE B 1 350 ? 166.598 164.624 139.010 1.00 52.84  ? 350 ILE B CB  1 
ATOM   6541  C  CG1 . ILE B 1 350 ? 166.927 165.587 137.877 1.00 52.84  ? 350 ILE B CG1 1 
ATOM   6542  C  CG2 . ILE B 1 350 ? 165.124 164.285 139.000 1.00 52.84  ? 350 ILE B CG2 1 
ATOM   6543  C  CD1 . ILE B 1 350 ? 166.186 166.881 137.974 1.00 52.84  ? 350 ILE B CD1 1 
ATOM   6544  N  N   . TYR B 1 351 ? 165.803 164.634 142.394 1.00 54.97  ? 351 TYR B N   1 
ATOM   6545  C  CA  . TYR B 1 351 ? 165.450 163.778 143.515 1.00 54.97  ? 351 TYR B CA  1 
ATOM   6546  C  C   . TYR B 1 351 ? 164.164 163.012 143.241 1.00 54.97  ? 351 TYR B C   1 
ATOM   6547  O  O   . TYR B 1 351 ? 163.269 163.489 142.540 1.00 54.97  ? 351 TYR B O   1 
ATOM   6548  C  CB  . TYR B 1 351 ? 165.283 164.566 144.815 1.00 54.97  ? 351 TYR B CB  1 
ATOM   6549  C  CG  . TYR B 1 351 ? 166.558 165.103 145.407 1.00 54.97  ? 351 TYR B CG  1 
ATOM   6550  C  CD1 . TYR B 1 351 ? 167.756 164.996 144.734 1.00 54.97  ? 351 TYR B CD1 1 
ATOM   6551  C  CD2 . TYR B 1 351 ? 166.579 165.611 146.692 1.00 54.97  ? 351 TYR B CD2 1 
ATOM   6552  C  CE1 . TYR B 1 351 ? 168.925 165.461 145.284 1.00 54.97  ? 351 TYR B CE1 1 
ATOM   6553  C  CE2 . TYR B 1 351 ? 167.748 166.064 147.257 1.00 54.97  ? 351 TYR B CE2 1 
ATOM   6554  C  CZ  . TYR B 1 351 ? 168.920 165.981 146.545 1.00 54.97  ? 351 TYR B CZ  1 
ATOM   6555  O  OH  . TYR B 1 351 ? 170.098 166.426 147.088 1.00 54.97  ? 351 TYR B OH  1 
ATOM   6556  N  N   . SER B 1 352 ? 164.082 161.819 143.824 1.00 51.12  ? 352 SER B N   1 
ATOM   6557  C  CA  . SER B 1 352 ? 162.904 160.961 143.775 1.00 51.12  ? 352 SER B CA  1 
ATOM   6558  C  C   . SER B 1 352 ? 162.518 160.518 145.180 1.00 51.12  ? 352 SER B C   1 
ATOM   6559  O  O   . SER B 1 352 ? 163.005 159.513 145.700 1.00 51.12  ? 352 SER B O   1 
ATOM   6560  C  CB  . SER B 1 352 ? 163.148 159.756 142.874 1.00 51.12  ? 352 SER B CB  1 
ATOM   6561  O  OG  . SER B 1 352 ? 162.038 158.878 142.879 1.00 51.12  ? 352 SER B OG  1 
ATOM   6562  N  N   . LEU B 1 353 ? 161.621 161.270 145.814 1.00 52.39  ? 353 LEU B N   1 
ATOM   6563  C  CA  . LEU B 1 353 ? 161.252 160.979 147.193 1.00 52.39  ? 353 LEU B CA  1 
ATOM   6564  C  C   . LEU B 1 353 ? 159.943 160.203 147.250 1.00 52.39  ? 353 LEU B C   1 
ATOM   6565  O  O   . LEU B 1 353 ? 159.054 160.386 146.414 1.00 52.39  ? 353 LEU B O   1 
ATOM   6566  C  CB  . LEU B 1 353 ? 161.120 162.273 148.000 1.00 52.39  ? 353 LEU B CB  1 
ATOM   6567  C  CG  . LEU B 1 353 ? 162.392 162.998 148.445 1.00 52.39  ? 353 LEU B CG  1 
ATOM   6568  C  CD1 . LEU B 1 353 ? 162.988 163.770 147.298 1.00 52.39  ? 353 LEU B CD1 1 
ATOM   6569  C  CD2 . LEU B 1 353 ? 162.138 163.919 149.621 1.00 52.39  ? 353 LEU B CD2 1 
ATOM   6570  N  N   . GLY B 1 354 ? 159.829 159.335 148.254 1.00 52.77  ? 354 GLY B N   1 
ATOM   6571  C  CA  . GLY B 1 354 ? 158.623 158.569 148.484 1.00 52.77  ? 354 GLY B CA  1 
ATOM   6572  C  C   . GLY B 1 354 ? 158.266 157.659 147.321 1.00 52.77  ? 354 GLY B C   1 
ATOM   6573  O  O   . GLY B 1 354 ? 159.065 157.383 146.428 1.00 52.77  ? 354 GLY B O   1 
ATOM   6574  N  N   . GLY B 1 355 ? 157.028 157.186 147.355 1.00 56.92  ? 355 GLY B N   1 
ATOM   6575  C  CA  . GLY B 1 355 ? 156.477 156.378 146.286 1.00 56.92  ? 355 GLY B CA  1 
ATOM   6576  C  C   . GLY B 1 355 ? 155.750 155.157 146.811 1.00 56.92  ? 355 GLY B C   1 
ATOM   6577  O  O   . GLY B 1 355 ? 155.907 154.739 147.955 1.00 56.92  ? 355 GLY B O   1 
ATOM   6578  N  N   . LYS B 1 356 ? 154.944 154.582 145.924 1.00 64.28  ? 356 LYS B N   1 
ATOM   6579  C  CA  . LYS B 1 356 ? 154.162 153.387 146.205 1.00 64.28  ? 356 LYS B CA  1 
ATOM   6580  C  C   . LYS B 1 356 ? 154.731 152.232 145.395 1.00 64.28  ? 356 LYS B C   1 
ATOM   6581  O  O   . LYS B 1 356 ? 154.855 152.332 144.170 1.00 64.28  ? 356 LYS B O   1 
ATOM   6582  C  CB  . LYS B 1 356 ? 152.687 153.617 145.872 1.00 64.28  ? 356 LYS B CB  1 
ATOM   6583  C  CG  . LYS B 1 356 ? 151.775 152.447 146.173 1.00 64.28  ? 356 LYS B CG  1 
ATOM   6584  C  CD  . LYS B 1 356 ? 150.322 152.837 145.968 1.00 64.28  ? 356 LYS B CD  1 
ATOM   6585  C  CE  . LYS B 1 356 ? 150.000 152.990 144.491 1.00 64.28  ? 356 LYS B CE  1 
ATOM   6586  N  NZ  . LYS B 1 356 ? 148.554 153.258 144.257 1.00 64.28  ? 356 LYS B NZ  1 
ATOM   6587  N  N   . THR B 1 357 ? 155.070 151.140 146.076 1.00 68.23  ? 357 THR B N   1 
ATOM   6588  C  CA  . THR B 1 357 ? 155.845 150.065 145.475 1.00 68.23  ? 357 THR B CA  1 
ATOM   6589  C  C   . THR B 1 357 ? 154.989 149.226 144.528 1.00 68.23  ? 357 THR B C   1 
ATOM   6590  O  O   . THR B 1 357 ? 153.879 149.601 144.139 1.00 68.23  ? 357 THR B O   1 
ATOM   6591  C  CB  . THR B 1 357 ? 156.457 149.184 146.560 1.00 68.23  ? 357 THR B CB  1 
ATOM   6592  O  OG1 . THR B 1 357 ? 155.412 148.541 147.295 1.00 68.23  ? 357 THR B OG1 1 
ATOM   6593  C  CG2 . THR B 1 357 ? 157.280 150.023 147.515 1.00 68.23  ? 357 THR B CG2 1 
ATOM   6594  N  N   . LEU B 1 358 ? 155.522 148.059 144.156 1.00 71.83  ? 358 LEU B N   1 
ATOM   6595  C  CA  . LEU B 1 358 ? 154.839 147.196 143.197 1.00 71.83  ? 358 LEU B CA  1 
ATOM   6596  C  C   . LEU B 1 358 ? 153.726 146.394 143.860 1.00 71.83  ? 358 LEU B C   1 
ATOM   6597  O  O   . LEU B 1 358 ? 152.696 146.120 143.234 1.00 71.83  ? 358 LEU B O   1 
ATOM   6598  C  CB  . LEU B 1 358 ? 155.842 146.260 142.527 1.00 71.83  ? 358 LEU B CB  1 
ATOM   6599  C  CG  . LEU B 1 358 ? 156.880 146.908 141.613 1.00 71.83  ? 358 LEU B CG  1 
ATOM   6600  C  CD1 . LEU B 1 358 ? 157.879 145.870 141.134 1.00 71.83  ? 358 LEU B CD1 1 
ATOM   6601  C  CD2 . LEU B 1 358 ? 156.201 147.588 140.437 1.00 71.83  ? 358 LEU B CD2 1 
ATOM   6602  N  N   . GLN B 1 359 ? 153.919 145.996 145.117 1.00 74.59  ? 359 GLN B N   1 
ATOM   6603  C  CA  . GLN B 1 359 ? 152.892 145.304 145.886 1.00 74.59  ? 359 GLN B CA  1 
ATOM   6604  C  C   . GLN B 1 359 ? 152.104 146.251 146.788 1.00 74.59  ? 359 GLN B C   1 
ATOM   6605  O  O   . GLN B 1 359 ? 151.645 145.850 147.863 1.00 74.59  ? 359 GLN B O   1 
ATOM   6606  C  CB  . GLN B 1 359 ? 153.509 144.162 146.695 1.00 74.59  ? 359 GLN B CB  1 
ATOM   6607  C  CG  . GLN B 1 359 ? 154.570 144.586 147.691 1.00 74.59  ? 359 GLN B CG  1 
ATOM   6608  C  CD  . GLN B 1 359 ? 155.954 144.598 147.075 1.00 74.59  ? 359 GLN B CD  1 
ATOM   6609  O  OE1 . GLN B 1 359 ? 156.101 144.567 145.853 1.00 74.59  ? 359 GLN B OE1 1 
ATOM   6610  N  NE2 . GLN B 1 359 ? 156.980 144.642 147.918 1.00 74.59  ? 359 GLN B NE2 1 
ATOM   6611  N  N   . ASP B 1 360 ? 151.944 147.505 146.362 1.00 73.80  ? 360 ASP B N   1 
ATOM   6612  C  CA  . ASP B 1 360 ? 151.051 148.473 146.999 1.00 73.80  ? 360 ASP B CA  1 
ATOM   6613  C  C   . ASP B 1 360 ? 151.456 148.744 148.450 1.00 73.80  ? 360 ASP B C   1 
ATOM   6614  O  O   . ASP B 1 360 ? 150.623 148.869 149.348 1.00 73.80  ? 360 ASP B O   1 
ATOM   6615  C  CB  . ASP B 1 360 ? 149.596 148.005 146.904 1.00 73.80  ? 360 ASP B CB  1 
ATOM   6616  C  CG  . ASP B 1 360 ? 149.074 148.020 145.481 1.00 73.80  ? 360 ASP B CG  1 
ATOM   6617  O  OD1 . ASP B 1 360 ? 149.550 148.853 144.681 1.00 73.80  ? 360 ASP B OD1 1 
ATOM   6618  O  OD2 . ASP B 1 360 ? 148.190 147.197 145.162 1.00 73.80  ? 360 ASP B OD2 1 
ATOM   6619  N  N   . THR B 1 361 ? 152.766 148.833 148.660 1.00 68.66  ? 361 THR B N   1 
ATOM   6620  C  CA  . THR B 1 361 ? 153.333 149.241 149.937 1.00 68.66  ? 361 THR B CA  1 
ATOM   6621  C  C   . THR B 1 361 ? 153.912 150.636 149.758 1.00 68.66  ? 361 THR B C   1 
ATOM   6622  O  O   . THR B 1 361 ? 154.298 151.012 148.648 1.00 68.66  ? 361 THR B O   1 
ATOM   6623  C  CB  . THR B 1 361 ? 154.412 148.251 150.411 1.00 68.66  ? 361 THR B CB  1 
ATOM   6624  O  OG1 . THR B 1 361 ? 153.859 146.930 150.458 1.00 68.66  ? 361 THR B OG1 1 
ATOM   6625  C  CG2 . THR B 1 361 ? 154.920 148.610 151.801 1.00 68.66  ? 361 THR B CG2 1 
ATOM   6626  N  N   . LEU B 1 362 ? 153.952 151.411 150.838 1.00 64.15  ? 362 LEU B N   1 
ATOM   6627  C  CA  . LEU B 1 362 ? 154.464 152.773 150.772 1.00 64.15  ? 362 LEU B CA  1 
ATOM   6628  C  C   . LEU B 1 362 ? 155.943 152.786 151.138 1.00 64.15  ? 362 LEU B C   1 
ATOM   6629  O  O   . LEU B 1 362 ? 156.320 152.391 152.247 1.00 64.15  ? 362 LEU B O   1 
ATOM   6630  C  CB  . LEU B 1 362 ? 153.665 153.685 151.698 1.00 64.15  ? 362 LEU B CB  1 
ATOM   6631  C  CG  . LEU B 1 362 ? 152.196 153.848 151.310 1.00 64.15  ? 362 LEU B CG  1 
ATOM   6632  C  CD1 . LEU B 1 362 ? 151.467 154.667 152.343 1.00 64.15  ? 362 LEU B CD1 1 
ATOM   6633  C  CD2 . LEU B 1 362 ? 152.067 154.480 149.945 1.00 64.15  ? 362 LEU B CD2 1 
ATOM   6634  N  N   . SER B 1 363 ? 156.778 153.233 150.208 1.00 62.90  ? 363 SER B N   1 
ATOM   6635  C  CA  . SER B 1 363 ? 158.213 153.339 150.421 1.00 62.90  ? 363 SER B CA  1 
ATOM   6636  C  C   . SER B 1 363 ? 158.571 154.732 150.923 1.00 62.90  ? 363 SER B C   1 
ATOM   6637  O  O   . SER B 1 363 ? 157.776 155.670 150.839 1.00 62.90  ? 363 SER B O   1 
ATOM   6638  C  CB  . SER B 1 363 ? 158.976 153.030 149.131 1.00 62.90  ? 363 SER B CB  1 
ATOM   6639  O  OG  . SER B 1 363 ? 160.372 153.175 149.316 1.00 62.90  ? 363 SER B OG  1 
ATOM   6640  N  N   . ASN B 1 364 ? 159.789 154.860 151.448 1.00 62.62  ? 364 ASN B N   1 
ATOM   6641  C  CA  . ASN B 1 364 ? 160.264 156.111 152.041 1.00 62.62  ? 364 ASN B CA  1 
ATOM   6642  C  C   . ASN B 1 364 ? 161.763 156.259 151.796 1.00 62.62  ? 364 ASN B C   1 
ATOM   6643  O  O   . ASN B 1 364 ? 162.501 156.691 152.683 1.00 62.62  ? 364 ASN B O   1 
ATOM   6644  C  CB  . ASN B 1 364 ? 159.928 156.162 153.533 1.00 62.62  ? 364 ASN B CB  1 
ATOM   6645  C  CG  . ASN B 1 364 ? 160.576 155.039 154.328 1.00 62.62  ? 364 ASN B CG  1 
ATOM   6646  O  OD1 . ASN B 1 364 ? 161.358 154.249 153.801 1.00 62.62  ? 364 ASN B OD1 1 
ATOM   6647  N  ND2 . ASN B 1 364 ? 160.252 154.971 155.613 1.00 62.62  ? 364 ASN B ND2 1 
ATOM   6648  N  N   . ALA B 1 365 ? 162.209 155.914 150.592 1.00 58.44  ? 365 ALA B N   1 
ATOM   6649  C  CA  . ALA B 1 365 ? 163.623 155.990 150.263 1.00 58.44  ? 365 ALA B CA  1 
ATOM   6650  C  C   . ALA B 1 365 ? 163.854 157.155 149.316 1.00 58.44  ? 365 ALA B C   1 
ATOM   6651  O  O   . ALA B 1 365 ? 163.036 157.429 148.435 1.00 58.44  ? 365 ALA B O   1 
ATOM   6652  C  CB  . ALA B 1 365 ? 164.127 154.687 149.636 1.00 58.44  ? 365 ALA B CB  1 
ATOM   6653  N  N   . VAL B 1 366 ? 164.980 157.837 149.507 1.00 57.11  ? 366 VAL B N   1 
ATOM   6654  C  CA  . VAL B 1 366 ? 165.376 158.971 148.679 1.00 57.11  ? 366 VAL B CA  1 
ATOM   6655  C  C   . VAL B 1 366 ? 166.529 158.528 147.792 1.00 57.11  ? 366 VAL B C   1 
ATOM   6656  O  O   . VAL B 1 366 ? 167.553 158.048 148.292 1.00 57.11  ? 366 VAL B O   1 
ATOM   6657  C  CB  . VAL B 1 366 ? 165.784 160.188 149.522 1.00 57.11  ? 366 VAL B CB  1 
ATOM   6658  C  CG1 . VAL B 1 366 ? 166.289 161.302 148.622 1.00 57.11  ? 366 VAL B CG1 1 
ATOM   6659  C  CG2 . VAL B 1 366 ? 164.625 160.668 150.357 1.00 57.11  ? 366 VAL B CG2 1 
ATOM   6660  N  N   . ILE B 1 367 ? 166.361 158.686 146.483 1.00 51.02  ? 367 ILE B N   1 
ATOM   6661  C  CA  . ILE B 1 367 ? 167.425 158.467 145.513 1.00 51.02  ? 367 ILE B CA  1 
ATOM   6662  C  C   . ILE B 1 367 ? 167.558 159.738 144.688 1.00 51.02  ? 367 ILE B C   1 
ATOM   6663  O  O   . ILE B 1 367 ? 166.557 160.408 144.414 1.00 51.02  ? 367 ILE B O   1 
ATOM   6664  C  CB  . ILE B 1 367 ? 167.142 157.246 144.614 1.00 51.02  ? 367 ILE B CB  1 
ATOM   6665  C  CG1 . ILE B 1 367 ? 165.858 157.443 143.813 1.00 51.02  ? 367 ILE B CG1 1 
ATOM   6666  C  CG2 . ILE B 1 367 ? 167.021 155.988 145.446 1.00 51.02  ? 367 ILE B CG2 1 
ATOM   6667  C  CD1 . ILE B 1 367 ? 165.624 156.370 142.783 1.00 51.02  ? 367 ILE B CD1 1 
ATOM   6668  N  N   . TYR B 1 368 ? 168.786 160.090 144.320 1.00 51.05  ? 368 TYR B N   1 
ATOM   6669  C  CA  . TYR B 1 368 ? 169.025 161.308 143.564 1.00 51.05  ? 368 TYR B CA  1 
ATOM   6670  C  C   . TYR B 1 368 ? 169.874 161.023 142.336 1.00 51.05  ? 368 TYR B C   1 
ATOM   6671  O  O   . TYR B 1 368 ? 170.491 159.960 142.223 1.00 51.05  ? 368 TYR B O   1 
ATOM   6672  C  CB  . TYR B 1 368 ? 169.688 162.388 144.421 1.00 51.05  ? 368 TYR B CB  1 
ATOM   6673  C  CG  . TYR B 1 368 ? 171.151 162.236 144.757 1.00 51.05  ? 368 TYR B CG  1 
ATOM   6674  C  CD1 . TYR B 1 368 ? 171.559 161.580 145.907 1.00 51.05  ? 368 TYR B CD1 1 
ATOM   6675  C  CD2 . TYR B 1 368 ? 172.125 162.814 143.951 1.00 51.05  ? 368 TYR B CD2 1 
ATOM   6676  C  CE1 . TYR B 1 368 ? 172.898 161.468 146.224 1.00 51.05  ? 368 TYR B CE1 1 
ATOM   6677  C  CE2 . TYR B 1 368 ? 173.462 162.706 144.258 1.00 51.05  ? 368 TYR B CE2 1 
ATOM   6678  C  CZ  . TYR B 1 368 ? 173.843 162.034 145.395 1.00 51.05  ? 368 TYR B CZ  1 
ATOM   6679  O  OH  . TYR B 1 368 ? 175.178 161.925 145.702 1.00 51.05  ? 368 TYR B OH  1 
ATOM   6680  N  N   . TYR B 1 369 ? 169.907 161.993 141.430 1.00 53.21  ? 369 TYR B N   1 
ATOM   6681  C  CA  . TYR B 1 369 ? 170.428 161.822 140.082 1.00 53.21  ? 369 TYR B CA  1 
ATOM   6682  C  C   . TYR B 1 369 ? 171.346 162.987 139.747 1.00 53.21  ? 369 TYR B C   1 
ATOM   6683  O  O   . TYR B 1 369 ? 170.882 164.124 139.609 1.00 53.21  ? 369 TYR B O   1 
ATOM   6684  C  CB  . TYR B 1 369 ? 169.274 161.737 139.085 1.00 53.21  ? 369 TYR B CB  1 
ATOM   6685  C  CG  . TYR B 1 369 ? 169.682 161.637 137.636 1.00 53.21  ? 369 TYR B CG  1 
ATOM   6686  C  CD1 . TYR B 1 369 ? 170.185 160.460 137.114 1.00 53.21  ? 369 TYR B CD1 1 
ATOM   6687  C  CD2 . TYR B 1 369 ? 169.537 162.716 136.785 1.00 53.21  ? 369 TYR B CD2 1 
ATOM   6688  C  CE1 . TYR B 1 369 ? 170.546 160.368 135.792 1.00 53.21  ? 369 TYR B CE1 1 
ATOM   6689  C  CE2 . TYR B 1 369 ? 169.896 162.630 135.462 1.00 53.21  ? 369 TYR B CE2 1 
ATOM   6690  C  CZ  . TYR B 1 369 ? 170.401 161.456 134.972 1.00 53.21  ? 369 TYR B CZ  1 
ATOM   6691  O  OH  . TYR B 1 369 ? 170.758 161.377 133.649 1.00 53.21  ? 369 TYR B OH  1 
ATOM   6692  N  N   . ARG B 1 370 ? 172.641 162.707 139.621 1.00 61.74  ? 370 ARG B N   1 
ATOM   6693  C  CA  . ARG B 1 370 ? 173.600 163.733 139.227 1.00 61.74  ? 370 ARG B CA  1 
ATOM   6694  C  C   . ARG B 1 370 ? 173.499 163.935 137.722 1.00 61.74  ? 370 ARG B C   1 
ATOM   6695  O  O   . ARG B 1 370 ? 173.954 163.091 136.943 1.00 61.74  ? 370 ARG B O   1 
ATOM   6696  C  CB  . ARG B 1 370 ? 175.016 163.343 139.636 1.00 61.74  ? 370 ARG B CB  1 
ATOM   6697  C  CG  . ARG B 1 370 ? 175.241 163.319 141.133 1.00 61.74  ? 370 ARG B CG  1 
ATOM   6698  C  CD  . ARG B 1 370 ? 176.680 162.966 141.458 1.00 61.74  ? 370 ARG B CD  1 
ATOM   6699  N  NE  . ARG B 1 370 ? 177.000 161.589 141.101 1.00 61.74  ? 370 ARG B NE  1 
ATOM   6700  C  CZ  . ARG B 1 370 ? 178.222 161.072 141.140 1.00 61.74  ? 370 ARG B CZ  1 
ATOM   6701  N  NH1 . ARG B 1 370 ? 179.250 161.822 141.516 1.00 61.74  ? 370 ARG B NH1 1 
ATOM   6702  N  NH2 . ARG B 1 370 ? 178.419 159.806 140.799 1.00 61.74  ? 370 ARG B NH2 1 
ATOM   6703  N  N   . VAL B 1 371 ? 172.905 165.058 137.313 1.00 59.03  ? 371 VAL B N   1 
ATOM   6704  C  CA  . VAL B 1 371 ? 172.646 165.303 135.896 1.00 59.03  ? 371 VAL B CA  1 
ATOM   6705  C  C   . VAL B 1 371 ? 173.952 165.377 135.115 1.00 59.03  ? 371 VAL B C   1 
ATOM   6706  O  O   . VAL B 1 371 ? 174.009 165.016 133.933 1.00 59.03  ? 371 VAL B O   1 
ATOM   6707  C  CB  . VAL B 1 371 ? 171.804 166.582 135.731 1.00 59.03  ? 371 VAL B CB  1 
ATOM   6708  C  CG1 . VAL B 1 371 ? 171.598 166.911 134.264 1.00 59.03  ? 371 VAL B CG1 1 
ATOM   6709  C  CG2 . VAL B 1 371 ? 170.469 166.421 136.433 1.00 59.03  ? 371 VAL B CG2 1 
ATOM   6710  N  N   . GLY B 1 372 ? 175.027 165.827 135.764 1.00 66.23  ? 372 GLY B N   1 
ATOM   6711  C  CA  . GLY B 1 372 ? 176.315 165.894 135.098 1.00 66.23  ? 372 GLY B CA  1 
ATOM   6712  C  C   . GLY B 1 372 ? 177.053 164.574 135.041 1.00 66.23  ? 372 GLY B C   1 
ATOM   6713  O  O   . GLY B 1 372 ? 178.151 164.516 134.481 1.00 66.23  ? 372 GLY B O   1 
ATOM   6714  N  N   . ASP B 1 373 ? 176.473 163.511 135.602 1.00 65.87  ? 373 ASP B N   1 
ATOM   6715  C  CA  . ASP B 1 373 ? 177.106 162.201 135.615 1.00 65.87  ? 373 ASP B CA  1 
ATOM   6716  C  C   . ASP B 1 373 ? 176.193 161.062 135.193 1.00 65.87  ? 373 ASP B C   1 
ATOM   6717  O  O   . ASP B 1 373 ? 176.699 159.967 134.923 1.00 65.87  ? 373 ASP B O   1 
ATOM   6718  C  CB  . ASP B 1 373 ? 177.655 161.881 137.016 1.00 65.87  ? 373 ASP B CB  1 
ATOM   6719  C  CG  . ASP B 1 373 ? 178.843 162.741 137.389 1.00 65.87  ? 373 ASP B CG  1 
ATOM   6720  O  OD1 . ASP B 1 373 ? 179.592 163.151 136.479 1.00 65.87  ? 373 ASP B OD1 1 
ATOM   6721  O  OD2 . ASP B 1 373 ? 179.029 163.005 138.595 1.00 65.87  ? 373 ASP B OD2 1 
ATOM   6722  N  N   . ASN B 1 374 ? 174.878 161.281 135.127 1.00 61.14  ? 374 ASN B N   1 
ATOM   6723  C  CA  . ASN B 1 374 ? 173.908 160.222 134.841 1.00 61.14  ? 374 ASN B CA  1 
ATOM   6724  C  C   . ASN B 1 374 ? 174.020 159.087 135.855 1.00 61.14  ? 374 ASN B C   1 
ATOM   6725  O  O   . ASN B 1 374 ? 174.029 157.908 135.497 1.00 61.14  ? 374 ASN B O   1 
ATOM   6726  C  CB  . ASN B 1 374 ? 174.061 159.687 133.415 1.00 61.14  ? 374 ASN B CB  1 
ATOM   6727  C  CG  . ASN B 1 374 ? 173.646 160.693 132.366 1.00 61.14  ? 374 ASN B CG  1 
ATOM   6728  O  OD1 . ASN B 1 374 ? 172.659 161.407 132.531 1.00 61.14  ? 374 ASN B OD1 1 
ATOM   6729  N  ND2 . ASN B 1 374 ? 174.395 160.749 131.272 1.00 61.14  ? 374 ASN B ND2 1 
ATOM   6730  N  N   . VAL B 1 375 ? 174.105 159.440 137.135 1.00 54.21  ? 375 VAL B N   1 
ATOM   6731  C  CA  . VAL B 1 375 ? 174.343 158.475 138.200 1.00 54.21  ? 375 VAL B CA  1 
ATOM   6732  C  C   . VAL B 1 375 ? 173.315 158.690 139.302 1.00 54.21  ? 375 VAL B C   1 
ATOM   6733  O  O   . VAL B 1 375 ? 173.109 159.821 139.758 1.00 54.21  ? 375 VAL B O   1 
ATOM   6734  C  CB  . VAL B 1 375 ? 175.775 158.584 138.755 1.00 54.21  ? 375 VAL B CB  1 
ATOM   6735  C  CG1 . VAL B 1 375 ? 175.959 157.656 139.941 1.00 54.21  ? 375 VAL B CG1 1 
ATOM   6736  C  CG2 . VAL B 1 375 ? 176.786 158.252 137.674 1.00 54.21  ? 375 VAL B CG2 1 
ATOM   6737  N  N   . TRP B 1 376 ? 172.673 157.602 139.717 1.00 48.12  ? 376 TRP B N   1 
ATOM   6738  C  CA  . TRP B 1 376 ? 171.737 157.607 140.832 1.00 48.12  ? 376 TRP B CA  1 
ATOM   6739  C  C   . TRP B 1 376 ? 172.451 157.161 142.099 1.00 48.12  ? 376 TRP B C   1 
ATOM   6740  O  O   . TRP B 1 376 ? 173.347 156.313 142.047 1.00 48.12  ? 376 TRP B O   1 
ATOM   6741  C  CB  . TRP B 1 376 ? 170.558 156.681 140.538 1.00 48.12  ? 376 TRP B CB  1 
ATOM   6742  C  CG  . TRP B 1 376 ? 169.640 157.202 139.491 1.00 48.12  ? 376 TRP B CG  1 
ATOM   6743  C  CD1 . TRP B 1 376 ? 169.703 156.963 138.154 1.00 48.12  ? 376 TRP B CD1 1 
ATOM   6744  C  CD2 . TRP B 1 376 ? 168.495 158.032 139.696 1.00 48.12  ? 376 TRP B CD2 1 
ATOM   6745  N  NE1 . TRP B 1 376 ? 168.679 157.606 137.509 1.00 48.12  ? 376 TRP B NE1 1 
ATOM   6746  C  CE2 . TRP B 1 376 ? 167.920 158.268 138.436 1.00 48.12  ? 376 TRP B CE2 1 
ATOM   6747  C  CE3 . TRP B 1 376 ? 167.903 158.604 140.824 1.00 48.12  ? 376 TRP B CE3 1 
ATOM   6748  C  CZ2 . TRP B 1 376 ? 166.783 159.051 138.272 1.00 48.12  ? 376 TRP B CZ2 1 
ATOM   6749  C  CZ3 . TRP B 1 376 ? 166.776 159.380 140.658 1.00 48.12  ? 376 TRP B CZ3 1 
ATOM   6750  C  CH2 . TRP B 1 376 ? 166.228 159.597 139.393 1.00 48.12  ? 376 TRP B CH2 1 
ATOM   6751  N  N   . THR B 1 377 ? 172.050 157.726 143.234 1.00 52.77  ? 377 THR B N   1 
ATOM   6752  C  CA  . THR B 1 377 ? 172.654 157.407 144.519 1.00 52.77  ? 377 THR B CA  1 
ATOM   6753  C  C   . THR B 1 377 ? 171.572 157.434 145.590 1.00 52.77  ? 377 THR B C   1 
ATOM   6754  O  O   . THR B 1 377 ? 170.571 158.139 145.449 1.00 52.77  ? 377 THR B O   1 
ATOM   6755  C  CB  . THR B 1 377 ? 173.782 158.397 144.850 1.00 52.77  ? 377 THR B CB  1 
ATOM   6756  O  OG1 . THR B 1 377 ? 174.736 158.403 143.782 1.00 52.77  ? 377 THR B OG1 1 
ATOM   6757  C  CG2 . THR B 1 377 ? 174.502 158.006 146.128 1.00 52.77  ? 377 THR B CG2 1 
ATOM   6758  N  N   . GLU B 1 378 ? 171.763 156.657 146.649 1.00 59.61  ? 378 GLU B N   1 
ATOM   6759  C  CA  . GLU B 1 378 ? 170.773 156.553 147.709 1.00 59.61  ? 378 GLU B CA  1 
ATOM   6760  C  C   . GLU B 1 378 ? 171.253 157.261 148.969 1.00 59.61  ? 378 GLU B C   1 
ATOM   6761  O  O   . GLU B 1 378 ? 172.341 156.987 149.483 1.00 59.61  ? 378 GLU B O   1 
ATOM   6762  C  CB  . GLU B 1 378 ? 170.479 155.085 148.012 1.00 59.61  ? 378 GLU B CB  1 
ATOM   6763  C  CG  . GLU B 1 378 ? 169.858 154.345 146.844 1.00 59.61  ? 378 GLU B CG  1 
ATOM   6764  C  CD  . GLU B 1 378 ? 169.618 152.881 147.138 1.00 59.61  ? 378 GLU B CD  1 
ATOM   6765  O  OE1 . GLU B 1 378 ? 170.058 152.409 148.208 1.00 59.61  ? 378 GLU B OE1 1 
ATOM   6766  O  OE2 . GLU B 1 378 ? 168.991 152.202 146.299 1.00 59.61  ? 378 GLU B OE2 1 
ATOM   6767  N  N   . THR B 1 379 ? 170.425 158.178 149.467 1.00 64.63  ? 379 THR B N   1 
ATOM   6768  C  CA  . THR B 1 379 ? 170.747 158.960 150.656 1.00 64.63  ? 379 THR B CA  1 
ATOM   6769  C  C   . THR B 1 379 ? 169.827 158.527 151.791 1.00 64.63  ? 379 THR B C   1 
ATOM   6770  O  O   . THR B 1 379 ? 169.190 157.471 151.734 1.00 64.63  ? 379 THR B O   1 
ATOM   6771  C  CB  . THR B 1 379 ? 170.635 160.465 150.381 1.00 64.63  ? 379 THR B CB  1 
ATOM   6772  O  OG1 . THR B 1 379 ? 169.314 160.779 149.927 1.00 64.63  ? 379 THR B OG1 1 
ATOM   6773  C  CG2 . THR B 1 379 ? 171.641 160.889 149.342 1.00 64.63  ? 379 THR B CG2 1 
ATOM   6774  N  N   . THR B 1 380 ? 169.769 159.354 152.833 1.00 70.24  ? 380 THR B N   1 
ATOM   6775  C  CA  . THR B 1 380 ? 168.979 159.025 154.011 1.00 70.24  ? 380 THR B CA  1 
ATOM   6776  C  C   . THR B 1 380 ? 167.500 158.945 153.660 1.00 70.24  ? 380 THR B C   1 
ATOM   6777  O  O   . THR B 1 380 ? 166.998 159.696 152.820 1.00 70.24  ? 380 THR B O   1 
ATOM   6778  C  CB  . THR B 1 380 ? 169.204 160.064 155.107 1.00 70.24  ? 380 THR B CB  1 
ATOM   6779  O  OG1 . THR B 1 380 ? 168.776 161.349 154.643 1.00 70.24  ? 380 THR B OG1 1 
ATOM   6780  C  CG2 . THR B 1 380 ? 170.676 160.136 155.466 1.00 70.24  ? 380 THR B CG2 1 
ATOM   6781  N  N   . GLN B 1 381 ? 166.802 158.028 154.316 1.00 66.65  ? 381 GLN B N   1 
ATOM   6782  C  CA  . GLN B 1 381 ? 165.410 157.756 154.010 1.00 66.65  ? 381 GLN B CA  1 
ATOM   6783  C  C   . GLN B 1 381 ? 164.485 158.693 154.781 1.00 66.65  ? 381 GLN B C   1 
ATOM   6784  O  O   . GLN B 1 381 ? 164.898 159.398 155.704 1.00 66.65  ? 381 GLN B O   1 
ATOM   6785  C  CB  . GLN B 1 381 ? 165.078 156.297 154.324 1.00 66.65  ? 381 GLN B CB  1 
ATOM   6786  C  CG  . GLN B 1 381 ? 165.189 155.927 155.786 1.00 66.65  ? 381 GLN B CG  1 
ATOM   6787  C  CD  . GLN B 1 381 ? 164.914 154.458 156.025 1.00 66.65  ? 381 GLN B CD  1 
ATOM   6788  O  OE1 . GLN B 1 381 ? 164.600 153.716 155.096 1.00 66.65  ? 381 GLN B OE1 1 
ATOM   6789  N  NE2 . GLN B 1 381 ? 165.028 154.030 157.276 1.00 66.65  ? 381 GLN B NE2 1 
ATOM   6790  N  N   . LEU B 1 382 ? 163.216 158.694 154.379 1.00 65.58  ? 382 LEU B N   1 
ATOM   6791  C  CA  . LEU B 1 382 ? 162.214 159.542 155.002 1.00 65.58  ? 382 LEU B CA  1 
ATOM   6792  C  C   . LEU B 1 382 ? 161.919 159.070 156.425 1.00 65.58  ? 382 LEU B C   1 
ATOM   6793  O  O   . LEU B 1 382 ? 162.433 158.053 156.898 1.00 65.58  ? 382 LEU B O   1 
ATOM   6794  C  CB  . LEU B 1 382 ? 160.918 159.538 154.191 1.00 65.58  ? 382 LEU B CB  1 
ATOM   6795  C  CG  . LEU B 1 382 ? 160.763 160.367 152.916 1.00 65.58  ? 382 LEU B CG  1 
ATOM   6796  C  CD1 . LEU B 1 382 ? 161.586 159.779 151.805 1.00 65.58  ? 382 LEU B CD1 1 
ATOM   6797  C  CD2 . LEU B 1 382 ? 159.308 160.401 152.506 1.00 65.58  ? 382 LEU B CD2 1 
ATOM   6798  N  N   . GLU B 1 383 ? 161.062 159.828 157.108 1.00 77.21  ? 383 GLU B N   1 
ATOM   6799  C  CA  . GLU B 1 383 ? 160.560 159.414 158.411 1.00 77.21  ? 383 GLU B CA  1 
ATOM   6800  C  C   . GLU B 1 383 ? 159.131 158.898 158.344 1.00 77.21  ? 383 GLU B C   1 
ATOM   6801  O  O   . GLU B 1 383 ? 158.707 158.151 159.233 1.00 77.21  ? 383 GLU B O   1 
ATOM   6802  C  CB  . GLU B 1 383 ? 160.648 160.572 159.407 1.00 77.21  ? 383 GLU B CB  1 
ATOM   6803  C  CG  . GLU B 1 383 ? 162.072 160.955 159.772 1.00 77.21  ? 383 GLU B CG  1 
ATOM   6804  C  CD  . GLU B 1 383 ? 162.131 162.082 160.782 1.00 77.21  ? 383 GLU B CD  1 
ATOM   6805  O  OE1 . GLU B 1 383 ? 161.066 162.649 161.101 1.00 77.21  ? 383 GLU B OE1 1 
ATOM   6806  O  OE2 . GLU B 1 383 ? 163.240 162.399 161.260 1.00 77.21  ? 383 GLU B OE2 1 
ATOM   6807  N  N   . VAL B 1 384 ? 158.379 159.280 157.314 1.00 69.04  ? 384 VAL B N   1 
ATOM   6808  C  CA  . VAL B 1 384 ? 157.045 158.750 157.061 1.00 69.04  ? 384 VAL B CA  1 
ATOM   6809  C  C   . VAL B 1 384 ? 156.940 158.437 155.576 1.00 69.04  ? 384 VAL B C   1 
ATOM   6810  O  O   . VAL B 1 384 ? 157.280 159.277 154.736 1.00 69.04  ? 384 VAL B O   1 
ATOM   6811  C  CB  . VAL B 1 384 ? 155.939 159.736 157.487 1.00 69.04  ? 384 VAL B CB  1 
ATOM   6812  C  CG1 . VAL B 1 384 ? 154.569 159.204 157.096 1.00 69.04  ? 384 VAL B CG1 1 
ATOM   6813  C  CG2 . VAL B 1 384 ? 156.001 160.000 158.981 1.00 69.04  ? 384 VAL B CG2 1 
ATOM   6814  N  N   . ALA B 1 385 ? 156.477 157.232 155.253 1.00 65.79  ? 385 ALA B N   1 
ATOM   6815  C  CA  . ALA B 1 385 ? 156.355 156.809 153.865 1.00 65.79  ? 385 ALA B CA  1 
ATOM   6816  C  C   . ALA B 1 385 ? 155.092 157.390 153.244 1.00 65.79  ? 385 ALA B C   1 
ATOM   6817  O  O   . ALA B 1 385 ? 153.990 157.200 153.766 1.00 65.79  ? 385 ALA B O   1 
ATOM   6818  C  CB  . ALA B 1 385 ? 156.338 155.285 153.775 1.00 65.79  ? 385 ALA B CB  1 
ATOM   6819  N  N   . VAL B 1 386 ? 155.255 158.098 152.125 1.00 63.47  ? 386 VAL B N   1 
ATOM   6820  C  CA  . VAL B 1 386 ? 154.148 158.743 151.433 1.00 63.47  ? 386 VAL B CA  1 
ATOM   6821  C  C   . VAL B 1 386 ? 154.216 158.398 149.952 1.00 63.47  ? 386 VAL B C   1 
ATOM   6822  O  O   . VAL B 1 386 ? 155.221 157.889 149.452 1.00 63.47  ? 386 VAL B O   1 
ATOM   6823  C  CB  . VAL B 1 386 ? 154.153 160.274 151.623 1.00 63.47  ? 386 VAL B CB  1 
ATOM   6824  C  CG1 . VAL B 1 386 ? 153.962 160.633 153.088 1.00 63.47  ? 386 VAL B CG1 1 
ATOM   6825  C  CG2 . VAL B 1 386 ? 155.445 160.865 151.089 1.00 63.47  ? 386 VAL B CG2 1 
ATOM   6826  N  N   . SER B 1 387 ? 153.125 158.691 149.248 1.00 64.99  ? 387 SER B N   1 
ATOM   6827  C  CA  . SER B 1 387 ? 153.036 158.445 147.817 1.00 64.99  ? 387 SER B CA  1 
ATOM   6828  C  C   . SER B 1 387 ? 152.111 159.469 147.183 1.00 64.99  ? 387 SER B C   1 
ATOM   6829  O  O   . SER B 1 387 ? 150.935 159.560 147.541 1.00 64.99  ? 387 SER B O   1 
ATOM   6830  C  CB  . SER B 1 387 ? 152.523 157.036 147.520 1.00 64.99  ? 387 SER B CB  1 
ATOM   6831  O  OG  . SER B 1 387 ? 151.171 156.897 147.919 1.00 64.99  ? 387 SER B OG  1 
ATOM   6832  N  N   . GLY B 1 388 ? 152.644 160.226 146.229 1.00 59.38  ? 388 GLY B N   1 
ATOM   6833  C  CA  . GLY B 1 388 ? 151.867 161.276 145.603 1.00 59.38  ? 388 GLY B CA  1 
ATOM   6834  C  C   . GLY B 1 388 ? 151.965 162.606 146.310 1.00 59.38  ? 388 GLY B C   1 
ATOM   6835  O  O   . GLY B 1 388 ? 151.109 163.473 146.110 1.00 59.38  ? 388 GLY B O   1 
ATOM   6836  N  N   . ALA B 1 389 ? 152.984 162.788 147.142 1.00 57.47  ? 389 ALA B N   1 
ATOM   6837  C  CA  . ALA B 1 389 ? 153.184 164.042 147.844 1.00 57.47  ? 389 ALA B CA  1 
ATOM   6838  C  C   . ALA B 1 389 ? 153.640 165.128 146.876 1.00 57.47  ? 389 ALA B C   1 
ATOM   6839  O  O   . ALA B 1 389 ? 154.381 164.876 145.923 1.00 57.47  ? 389 ALA B O   1 
ATOM   6840  C  CB  . ALA B 1 389 ? 154.211 163.875 148.963 1.00 57.47  ? 389 ALA B CB  1 
ATOM   6841  N  N   . ALA B 1 390 ? 153.181 166.349 147.129 1.00 55.62  ? 390 ALA B N   1 
ATOM   6842  C  CA  . ALA B 1 390 ? 153.558 167.504 146.325 1.00 55.62  ? 390 ALA B CA  1 
ATOM   6843  C  C   . ALA B 1 390 ? 154.853 168.083 146.876 1.00 55.62  ? 390 ALA B C   1 
ATOM   6844  O  O   . ALA B 1 390 ? 154.864 168.662 147.966 1.00 55.62  ? 390 ALA B O   1 
ATOM   6845  C  CB  . ALA B 1 390 ? 152.454 168.558 146.325 1.00 55.62  ? 390 ALA B CB  1 
ATOM   6846  N  N   . GLY B 1 391 ? 155.942 167.926 146.124 1.00 54.46  ? 391 GLY B N   1 
ATOM   6847  C  CA  . GLY B 1 391 ? 157.246 168.396 146.549 1.00 54.46  ? 391 GLY B CA  1 
ATOM   6848  C  C   . GLY B 1 391 ? 157.531 169.781 145.993 1.00 54.46  ? 391 GLY B C   1 
ATOM   6849  O  O   . GLY B 1 391 ? 157.113 170.114 144.883 1.00 54.46  ? 391 GLY B O   1 
ATOM   6850  N  N   . ALA B 1 392 ? 158.251 170.577 146.779 1.00 56.52  ? 392 ALA B N   1 
ATOM   6851  C  CA  . ALA B 1 392 ? 158.595 171.941 146.396 1.00 56.52  ? 392 ALA B CA  1 
ATOM   6852  C  C   . ALA B 1 392 ? 159.951 172.284 146.987 1.00 56.52  ? 392 ALA B C   1 
ATOM   6853  O  O   . ALA B 1 392 ? 160.134 172.207 148.205 1.00 56.52  ? 392 ALA B O   1 
ATOM   6854  C  CB  . ALA B 1 392 ? 157.530 172.933 146.873 1.00 56.52  ? 392 ALA B CB  1 
ATOM   6855  N  N   . ASN B 1 393 ? 160.893 172.667 146.134 1.00 62.40  ? 393 ASN B N   1 
ATOM   6856  C  CA  . ASN B 1 393 ? 162.258 172.927 146.560 1.00 62.40  ? 393 ASN B CA  1 
ATOM   6857  C  C   . ASN B 1 393 ? 162.477 174.409 146.829 1.00 62.40  ? 393 ASN B C   1 
ATOM   6858  O  O   . ASN B 1 393 ? 162.437 175.239 145.918 1.00 62.40  ? 393 ASN B O   1 
ATOM   6859  C  CB  . ASN B 1 393 ? 163.252 172.441 145.504 1.00 62.40  ? 393 ASN B CB  1 
ATOM   6860  C  CG  . ASN B 1 393 ? 164.687 172.470 145.993 1.00 62.40  ? 393 ASN B CG  1 
ATOM   6861  O  OD1 . ASN B 1 393 ? 164.969 172.905 147.106 1.00 62.40  ? 393 ASN B OD1 1 
ATOM   6862  N  ND2 . ASN B 1 393 ? 165.601 171.986 145.164 1.00 62.40  ? 393 ASN B ND2 1 
ATOM   6863  N  N   . LEU B 1 394 ? 162.723 174.732 148.098 1.00 64.11  ? 394 LEU B N   1 
ATOM   6864  C  CA  . LEU B 1 394 ? 163.079 176.090 148.489 1.00 64.11  ? 394 LEU B CA  1 
ATOM   6865  C  C   . LEU B 1 394 ? 164.585 176.212 148.669 1.00 64.11  ? 394 LEU B C   1 
ATOM   6866  O  O   . LEU B 1 394 ? 165.147 175.607 149.587 1.00 64.11  ? 394 LEU B O   1 
ATOM   6867  C  CB  . LEU B 1 394 ? 162.363 176.498 149.776 1.00 64.11  ? 394 LEU B CB  1 
ATOM   6868  C  CG  . LEU B 1 394 ? 160.986 177.143 149.637 1.00 64.11  ? 394 LEU B CG  1 
ATOM   6869  C  CD1 . LEU B 1 394 ? 161.103 178.459 148.889 1.00 64.11  ? 394 LEU B CD1 1 
ATOM   6870  C  CD2 . LEU B 1 394 ? 160.018 176.215 148.940 1.00 64.11  ? 394 LEU B CD2 1 
ATOM   6871  N  N   . ASN B 1 395 ? 165.222 176.997 147.791 1.00 71.67  ? 395 ASN B N   1 
ATOM   6872  C  CA  . ASN B 1 395 ? 166.670 177.260 147.760 1.00 71.67  ? 395 ASN B CA  1 
ATOM   6873  C  C   . ASN B 1 395 ? 167.504 176.201 148.481 1.00 71.67  ? 395 ASN B C   1 
ATOM   6874  O  O   . ASN B 1 395 ? 168.361 176.525 149.307 1.00 71.67  ? 395 ASN B O   1 
ATOM   6875  C  CB  . ASN B 1 395 ? 166.990 178.663 148.298 1.00 71.67  ? 395 ASN B CB  1 
ATOM   6876  C  CG  . ASN B 1 395 ? 166.600 178.855 149.755 1.00 71.67  ? 395 ASN B CG  1 
ATOM   6877  O  OD1 . ASN B 1 395 ? 166.223 177.914 150.448 1.00 71.67  ? 395 ASN B OD1 1 
ATOM   6878  N  ND2 . ASN B 1 395 ? 166.691 180.093 150.224 1.00 71.67  ? 395 ASN B ND2 1 
ATOM   6879  N  N   . GLY B 1 396 ? 167.270 174.929 148.170 1.00 67.77  ? 396 GLY B N   1 
ATOM   6880  C  CA  . GLY B 1 396 ? 168.071 173.861 148.731 1.00 67.77  ? 396 GLY B CA  1 
ATOM   6881  C  C   . GLY B 1 396 ? 167.415 173.102 149.866 1.00 67.77  ? 396 GLY B C   1 
ATOM   6882  O  O   . GLY B 1 396 ? 168.108 172.549 150.724 1.00 67.77  ? 396 GLY B O   1 
ATOM   6883  N  N   . ILE B 1 397 ? 166.084 173.071 149.888 1.00 62.47  ? 397 ILE B N   1 
ATOM   6884  C  CA  . ILE B 1 397 ? 165.320 172.295 150.861 1.00 62.47  ? 397 ILE B CA  1 
ATOM   6885  C  C   . ILE B 1 397 ? 164.075 171.770 150.163 1.00 62.47  ? 397 ILE B C   1 
ATOM   6886  O  O   . ILE B 1 397 ? 163.273 172.556 149.647 1.00 62.47  ? 397 ILE B O   1 
ATOM   6887  C  CB  . ILE B 1 397 ? 164.918 173.116 152.100 1.00 62.47  ? 397 ILE B CB  1 
ATOM   6888  C  CG1 . ILE B 1 397 ? 166.139 173.497 152.938 1.00 62.47  ? 397 ILE B CG1 1 
ATOM   6889  C  CG2 . ILE B 1 397 ? 163.927 172.345 152.937 1.00 62.47  ? 397 ILE B CG2 1 
ATOM   6890  C  CD1 . ILE B 1 397 ? 165.835 174.494 154.024 1.00 62.47  ? 397 ILE B CD1 1 
ATOM   6891  N  N   . ILE B 1 398 ? 163.904 170.452 150.148 1.00 58.66  ? 398 ILE B N   1 
ATOM   6892  C  CA  . ILE B 1 398 ? 162.764 169.814 149.501 1.00 58.66  ? 398 ILE B CA  1 
ATOM   6893  C  C   . ILE B 1 398 ? 161.656 169.634 150.526 1.00 58.66  ? 398 ILE B C   1 
ATOM   6894  O  O   . ILE B 1 398 ? 161.873 169.045 151.591 1.00 58.66  ? 398 ILE B O   1 
ATOM   6895  C  CB  . ILE B 1 398 ? 163.156 168.466 148.873 1.00 58.66  ? 398 ILE B CB  1 
ATOM   6896  C  CG1 . ILE B 1 398 ? 164.094 168.676 147.683 1.00 58.66  ? 398 ILE B CG1 1 
ATOM   6897  C  CG2 . ILE B 1 398 ? 161.919 167.696 148.451 1.00 58.66  ? 398 ILE B CG2 1 
ATOM   6898  C  CD1 . ILE B 1 398 ? 165.557 168.688 148.039 1.00 58.66  ? 398 ILE B CD1 1 
ATOM   6899  N  N   . TYR B 1 399 ? 160.469 170.139 150.208 1.00 56.76  ? 399 TYR B N   1 
ATOM   6900  C  CA  . TYR B 1 399 ? 159.295 170.008 151.058 1.00 56.76  ? 399 TYR B CA  1 
ATOM   6901  C  C   . TYR B 1 399 ? 158.339 168.994 150.450 1.00 56.76  ? 399 TYR B C   1 
ATOM   6902  O  O   . TYR B 1 399 ? 157.944 169.127 149.287 1.00 56.76  ? 399 TYR B O   1 
ATOM   6903  C  CB  . TYR B 1 399 ? 158.591 171.354 151.235 1.00 56.76  ? 399 TYR B CB  1 
ATOM   6904  C  CG  . TYR B 1 399 ? 159.338 172.322 152.119 1.00 56.76  ? 399 TYR B CG  1 
ATOM   6905  C  CD1 . TYR B 1 399 ? 159.212 172.265 153.498 1.00 56.76  ? 399 TYR B CD1 1 
ATOM   6906  C  CD2 . TYR B 1 399 ? 160.177 173.283 151.580 1.00 56.76  ? 399 TYR B CD2 1 
ATOM   6907  C  CE1 . TYR B 1 399 ? 159.890 173.140 154.313 1.00 56.76  ? 399 TYR B CE1 1 
ATOM   6908  C  CE2 . TYR B 1 399 ? 160.861 174.163 152.391 1.00 56.76  ? 399 TYR B CE2 1 
ATOM   6909  C  CZ  . TYR B 1 399 ? 160.713 174.085 153.756 1.00 56.76  ? 399 TYR B CZ  1 
ATOM   6910  O  OH  . TYR B 1 399 ? 161.392 174.959 154.571 1.00 56.76  ? 399 TYR B OH  1 
ATOM   6911  N  N   . LEU B 1 400 ? 157.975 167.985 151.237 1.00 56.61  ? 400 LEU B N   1 
ATOM   6912  C  CA  . LEU B 1 400 ? 156.969 167.001 150.852 1.00 56.61  ? 400 LEU B CA  1 
ATOM   6913  C  C   . LEU B 1 400 ? 155.655 167.405 151.503 1.00 56.61  ? 400 LEU B C   1 
ATOM   6914  O  O   . LEU B 1 400 ? 155.564 167.486 152.734 1.00 56.61  ? 400 LEU B O   1 
ATOM   6915  C  CB  . LEU B 1 400 ? 157.379 165.593 151.267 1.00 56.61  ? 400 LEU B CB  1 
ATOM   6916  C  CG  . LEU B 1 400 ? 158.565 165.011 150.507 1.00 56.61  ? 400 LEU B CG  1 
ATOM   6917  C  CD1 . LEU B 1 400 ? 158.936 163.676 151.098 1.00 56.61  ? 400 LEU B CD1 1 
ATOM   6918  C  CD2 . LEU B 1 400 ? 158.220 164.872 149.038 1.00 56.61  ? 400 LEU B CD2 1 
ATOM   6919  N  N   . LEU B 1 401 ? 154.646 167.652 150.674 1.00 55.95  ? 401 LEU B N   1 
ATOM   6920  C  CA  . LEU B 1 401 ? 153.385 168.241 151.097 1.00 55.95  ? 401 LEU B CA  1 
ATOM   6921  C  C   . LEU B 1 401 ? 152.269 167.231 150.873 1.00 55.95  ? 401 LEU B C   1 
ATOM   6922  O  O   . LEU B 1 401 ? 151.935 166.920 149.724 1.00 55.95  ? 401 LEU B O   1 
ATOM   6923  C  CB  . LEU B 1 401 ? 153.104 169.523 150.313 1.00 55.95  ? 401 LEU B CB  1 
ATOM   6924  C  CG  . LEU B 1 401 ? 154.121 170.663 150.406 1.00 55.95  ? 401 LEU B CG  1 
ATOM   6925  C  CD1 . LEU B 1 401 ? 153.780 171.747 149.407 1.00 55.95  ? 401 LEU B CD1 1 
ATOM   6926  C  CD2 . LEU B 1 401 ? 154.193 171.243 151.798 1.00 55.95  ? 401 LEU B CD2 1 
ATOM   6927  N  N   . GLY B 1 402 ? 151.704 166.720 151.963 1.00 60.23  ? 402 GLY B N   1 
ATOM   6928  C  CA  . GLY B 1 402 ? 150.543 165.852 151.912 1.00 60.23  ? 402 GLY B CA  1 
ATOM   6929  C  C   . GLY B 1 402 ? 150.788 164.579 151.123 1.00 60.23  ? 402 GLY B C   1 
ATOM   6930  O  O   . GLY B 1 402 ? 151.836 163.933 151.227 1.00 60.23  ? 402 GLY B O   1 
ATOM   6931  N  N   . GLY B 1 403 ? 149.792 164.207 150.325 1.00 69.14  ? 403 GLY B N   1 
ATOM   6932  C  CA  . GLY B 1 403 ? 149.900 163.041 149.472 1.00 69.14  ? 403 GLY B CA  1 
ATOM   6933  C  C   . GLY B 1 403 ? 148.999 161.893 149.878 1.00 69.14  ? 403 GLY B C   1 
ATOM   6934  O  O   . GLY B 1 403 ? 147.778 161.962 149.718 1.00 69.14  ? 403 GLY B O   1 
ATOM   6935  N  N   . GLU B 1 404 ? 149.598 160.828 150.400 1.00 75.67  ? 404 GLU B N   1 
ATOM   6936  C  CA  . GLU B 1 404 ? 148.878 159.633 150.812 1.00 75.67  ? 404 GLU B CA  1 
ATOM   6937  C  C   . GLU B 1 404 ? 149.733 158.885 151.822 1.00 75.67  ? 404 GLU B C   1 
ATOM   6938  O  O   . GLU B 1 404 ? 150.923 158.660 151.590 1.00 75.67  ? 404 GLU B O   1 
ATOM   6939  C  CB  . GLU B 1 404 ? 148.556 158.746 149.611 1.00 75.67  ? 404 GLU B CB  1 
ATOM   6940  C  CG  . GLU B 1 404 ? 147.682 157.550 149.917 1.00 75.67  ? 404 GLU B CG  1 
ATOM   6941  C  CD  . GLU B 1 404 ? 147.352 156.754 148.669 1.00 75.67  ? 404 GLU B CD  1 
ATOM   6942  O  OE1 . GLU B 1 404 ? 147.851 157.118 147.585 1.00 75.67  ? 404 GLU B OE1 1 
ATOM   6943  O  OE2 . GLU B 1 404 ? 146.588 155.773 148.767 1.00 75.67  ? 404 GLU B OE2 1 
ATOM   6944  N  N   . GLU B 1 405 ? 149.126 158.508 152.942 1.00 85.03  ? 405 GLU B N   1 
ATOM   6945  C  CA  . GLU B 1 405 ? 149.859 158.040 154.108 1.00 85.03  ? 405 GLU B CA  1 
ATOM   6946  C  C   . GLU B 1 405 ? 149.397 156.642 154.490 1.00 85.03  ? 405 GLU B C   1 
ATOM   6947  O  O   . GLU B 1 405 ? 148.272 156.238 154.188 1.00 85.03  ? 405 GLU B O   1 
ATOM   6948  C  CB  . GLU B 1 405 ? 149.662 159.003 155.290 1.00 85.03  ? 405 GLU B CB  1 
ATOM   6949  C  CG  . GLU B 1 405 ? 150.473 158.688 156.532 1.00 85.03  ? 405 GLU B CG  1 
ATOM   6950  C  CD  . GLU B 1 405 ? 150.230 159.685 157.648 1.00 85.03  ? 405 GLU B CD  1 
ATOM   6951  O  OE1 . GLU B 1 405 ? 149.414 160.608 157.452 1.00 85.03  ? 405 GLU B OE1 1 
ATOM   6952  O  OE2 . GLU B 1 405 ? 150.851 159.544 158.722 1.00 85.03  ? 405 GLU B OE2 1 
ATOM   6953  N  N   . ASN B 1 406 ? 150.284 155.904 155.154 1.00 91.96  ? 406 ASN B N   1 
ATOM   6954  C  CA  . ASN B 1 406 ? 149.923 154.594 155.674 1.00 91.96  ? 406 ASN B CA  1 
ATOM   6955  C  C   . ASN B 1 406 ? 148.993 154.752 156.870 1.00 91.96  ? 406 ASN B C   1 
ATOM   6956  O  O   . ASN B 1 406 ? 149.332 155.404 157.860 1.00 91.96  ? 406 ASN B O   1 
ATOM   6957  C  CB  . ASN B 1 406 ? 151.180 153.820 156.073 1.00 91.96  ? 406 ASN B CB  1 
ATOM   6958  C  CG  . ASN B 1 406 ? 150.900 152.360 156.360 1.00 91.96  ? 406 ASN B CG  1 
ATOM   6959  O  OD1 . ASN B 1 406 ? 149.759 151.907 156.285 1.00 91.96  ? 406 ASN B OD1 1 
ATOM   6960  N  ND2 . ASN B 1 406 ? 151.948 151.611 156.686 1.00 91.96  ? 406 ASN B ND2 1 
ATOM   6961  N  N   . ASP B 1 407 ? 147.812 154.153 156.769 1.00 99.00  ? 407 ASP B N   1 
ATOM   6962  C  CA  . ASP B 1 407 ? 146.757 154.312 157.758 1.00 99.00  ? 407 ASP B CA  1 
ATOM   6963  C  C   . ASP B 1 407 ? 147.104 153.573 159.046 1.00 99.00  ? 407 ASP B C   1 
ATOM   6964  O  O   . ASP B 1 407 ? 147.986 153.975 159.808 1.00 99.00  ? 407 ASP B O   1 
ATOM   6965  C  CB  . ASP B 1 407 ? 145.422 153.808 157.202 1.00 99.00  ? 407 ASP B CB  1 
ATOM   6966  C  CG  . ASP B 1 407 ? 144.247 154.142 158.103 1.00 99.00  ? 407 ASP B CG  1 
ATOM   6967  O  OD1 . ASP B 1 407 ? 143.823 155.316 158.126 1.00 99.00  ? 407 ASP B OD1 1 
ATOM   6968  O  OD2 . ASP B 1 407 ? 143.750 153.227 158.791 1.00 99.00  ? 407 ASP B OD2 1 
ATOM   6969  N  N   . LEU B 1 408 ? 146.384 152.474 159.282 1.00 106.39 ? 408 LEU B N   1 
ATOM   6970  C  CA  . LEU B 1 408 ? 146.593 151.697 160.498 1.00 106.39 ? 408 LEU B CA  1 
ATOM   6971  C  C   . LEU B 1 408 ? 146.167 150.250 160.296 1.00 106.39 ? 408 LEU B C   1 
ATOM   6972  O  O   . LEU B 1 408 ? 146.794 149.327 160.830 1.00 106.39 ? 408 LEU B O   1 
ATOM   6973  C  CB  . LEU B 1 408 ? 145.828 152.327 161.662 1.00 106.39 ? 408 LEU B CB  1 
ATOM   6974  C  CG  . LEU B 1 408 ? 145.999 151.672 163.033 1.00 106.39 ? 408 LEU B CG  1 
ATOM   6975  C  CD1 . LEU B 1 408 ? 147.448 151.751 163.489 1.00 106.39 ? 408 LEU B CD1 1 
ATOM   6976  C  CD2 . LEU B 1 408 ? 145.078 152.326 164.050 1.00 106.39 ? 408 LEU B CD2 1 
ATOM   6977  N  N   . ASP B 1 409 ? 145.101 150.034 159.528 1.00 110.08 ? 409 ASP B N   1 
ATOM   6978  C  CA  . ASP B 1 409 ? 144.670 148.698 159.122 1.00 110.08 ? 409 ASP B CA  1 
ATOM   6979  C  C   . ASP B 1 409 ? 145.390 148.247 157.857 1.00 110.08 ? 409 ASP B C   1 
ATOM   6980  O  O   . ASP B 1 409 ? 144.833 147.521 157.028 1.00 110.08 ? 409 ASP B O   1 
ATOM   6981  C  CB  . ASP B 1 409 ? 143.156 148.690 158.930 1.00 110.08 ? 409 ASP B CB  1 
ATOM   6982  C  CG  . ASP B 1 409 ? 142.572 147.288 158.885 1.00 110.08 ? 409 ASP B CG  1 
ATOM   6983  O  OD1 . ASP B 1 409 ? 143.342 146.311 158.999 1.00 110.08 ? 409 ASP B OD1 1 
ATOM   6984  O  OD2 . ASP B 1 409 ? 141.338 147.165 158.736 1.00 110.08 ? 409 ASP B OD2 1 
ATOM   6985  N  N   . PHE B 1 410 ? 146.641 148.685 157.691 1.00 111.56 ? 410 PHE B N   1 
ATOM   6986  C  CA  . PHE B 1 410 ? 147.439 148.416 156.493 1.00 111.56 ? 410 PHE B CA  1 
ATOM   6987  C  C   . PHE B 1 410 ? 146.754 148.943 155.234 1.00 111.56 ? 410 PHE B C   1 
ATOM   6988  O  O   . PHE B 1 410 ? 146.888 148.374 154.148 1.00 111.56 ? 410 PHE B O   1 
ATOM   6989  C  CB  . PHE B 1 410 ? 147.765 146.926 156.360 1.00 111.56 ? 410 PHE B CB  1 
ATOM   6990  C  CG  . PHE B 1 410 ? 148.726 146.424 157.401 1.00 111.56 ? 410 PHE B CG  1 
ATOM   6991  C  CD1 . PHE B 1 410 ? 149.466 147.313 158.165 1.00 111.56 ? 410 PHE B CD1 1 
ATOM   6992  C  CD2 . PHE B 1 410 ? 148.890 145.066 157.615 1.00 111.56 ? 410 PHE B CD2 1 
ATOM   6993  C  CE1 . PHE B 1 410 ? 150.350 146.857 159.125 1.00 111.56 ? 410 PHE B CE1 1 
ATOM   6994  C  CE2 . PHE B 1 410 ? 149.774 144.603 158.574 1.00 111.56 ? 410 PHE B CE2 1 
ATOM   6995  C  CZ  . PHE B 1 410 ? 150.504 145.500 159.329 1.00 111.56 ? 410 PHE B CZ  1 
ATOM   6996  N  N   . PHE B 1 411 ? 146.015 150.037 155.377 1.00 104.31 ? 411 PHE B N   1 
ATOM   6997  C  CA  . PHE B 1 411 ? 145.437 150.767 154.259 1.00 104.31 ? 411 PHE B CA  1 
ATOM   6998  C  C   . PHE B 1 411 ? 146.148 152.112 154.124 1.00 104.31 ? 411 PHE B C   1 
ATOM   6999  O  O   . PHE B 1 411 ? 147.253 152.311 154.638 1.00 104.31 ? 411 PHE B O   1 
ATOM   7000  C  CB  . PHE B 1 411 ? 143.927 150.943 154.438 1.00 104.31 ? 411 PHE B CB  1 
ATOM   7001  C  CG  . PHE B 1 411 ? 143.146 149.670 154.289 1.00 104.31 ? 411 PHE B CG  1 
ATOM   7002  C  CD1 . PHE B 1 411 ? 142.859 149.163 153.032 1.00 104.31 ? 411 PHE B CD1 1 
ATOM   7003  C  CD2 . PHE B 1 411 ? 142.688 148.988 155.402 1.00 104.31 ? 411 PHE B CD2 1 
ATOM   7004  C  CE1 . PHE B 1 411 ? 142.138 147.994 152.889 1.00 104.31 ? 411 PHE B CE1 1 
ATOM   7005  C  CE2 . PHE B 1 411 ? 141.967 147.818 155.266 1.00 104.31 ? 411 PHE B CE2 1 
ATOM   7006  C  CZ  . PHE B 1 411 ? 141.691 147.321 154.008 1.00 104.31 ? 411 PHE B CZ  1 
ATOM   7007  N  N   . THR B 1 412 ? 145.503 153.041 153.424 1.00 94.17  ? 412 THR B N   1 
ATOM   7008  C  CA  . THR B 1 412 ? 146.054 154.371 153.183 1.00 94.17  ? 412 THR B CA  1 
ATOM   7009  C  C   . THR B 1 412 ? 145.005 155.407 153.563 1.00 94.17  ? 412 THR B C   1 
ATOM   7010  O  O   . THR B 1 412 ? 143.820 155.081 153.680 1.00 94.17  ? 412 THR B O   1 
ATOM   7011  C  CB  . THR B 1 412 ? 146.475 154.538 151.723 1.00 94.17  ? 412 THR B CB  1 
ATOM   7012  O  OG1 . THR B 1 412 ? 145.333 154.366 150.874 1.00 94.17  ? 412 THR B OG1 1 
ATOM   7013  C  CG2 . THR B 1 412 ? 147.540 153.516 151.348 1.00 94.17  ? 412 THR B CG2 1 
ATOM   7014  N  N   . LYS B 1 413 ? 145.437 156.642 153.752 1.00 88.07  ? 413 LYS B N   1 
ATOM   7015  C  CA  . LYS B 1 413 ? 144.559 157.746 154.091 1.00 88.07  ? 413 LYS B CA  1 
ATOM   7016  C  C   . LYS B 1 413 ? 145.163 159.064 153.635 1.00 88.07  ? 413 LYS B C   1 
ATOM   7017  O  O   . LYS B 1 413 ? 146.385 159.200 153.535 1.00 88.07  ? 413 LYS B O   1 
ATOM   7018  C  CB  . LYS B 1 413 ? 144.310 157.785 155.602 1.00 88.07  ? 413 LYS B CB  1 
ATOM   7019  C  CG  . LYS B 1 413 ? 145.535 158.143 156.424 1.00 88.07  ? 413 LYS B CG  1 
ATOM   7020  C  CD  . LYS B 1 413 ? 145.214 158.185 157.906 1.00 88.07  ? 413 LYS B CD  1 
ATOM   7021  C  CE  . LYS B 1 413 ? 146.450 158.494 158.727 1.00 88.07  ? 413 LYS B CE  1 
ATOM   7022  N  NZ  . LYS B 1 413 ? 146.958 159.865 158.461 1.00 88.07  ? 413 LYS B NZ  1 
ATOM   7023  N  N   . PRO B 1 414 ? 144.332 160.059 153.327 1.00 80.47  ? 414 PRO B N   1 
ATOM   7024  C  CA  . PRO B 1 414 ? 144.869 161.370 152.949 1.00 80.47  ? 414 PRO B CA  1 
ATOM   7025  C  C   . PRO B 1 414 ? 145.726 161.955 154.060 1.00 80.47  ? 414 PRO B C   1 
ATOM   7026  O  O   . PRO B 1 414 ? 145.322 162.018 155.222 1.00 80.47  ? 414 PRO B O   1 
ATOM   7027  C  CB  . PRO B 1 414 ? 143.611 162.210 152.709 1.00 80.47  ? 414 PRO B CB  1 
ATOM   7028  C  CG  . PRO B 1 414 ? 142.559 161.213 152.373 1.00 80.47  ? 414 PRO B CG  1 
ATOM   7029  C  CD  . PRO B 1 414 ? 142.866 160.010 153.209 1.00 80.47  ? 414 PRO B CD  1 
ATOM   7030  N  N   . SER B 1 415 ? 146.927 162.383 153.689 1.00 73.04  ? 415 SER B N   1 
ATOM   7031  C  CA  . SER B 1 415 ? 147.912 162.870 154.640 1.00 73.04  ? 415 SER B CA  1 
ATOM   7032  C  C   . SER B 1 415 ? 147.870 164.389 154.736 1.00 73.04  ? 415 SER B C   1 
ATOM   7033  O  O   . SER B 1 415 ? 147.524 165.090 153.781 1.00 73.04  ? 415 SER B O   1 
ATOM   7034  C  CB  . SER B 1 415 ? 149.321 162.417 154.246 1.00 73.04  ? 415 SER B CB  1 
ATOM   7035  O  OG  . SER B 1 415 ? 150.288 162.911 155.154 1.00 73.04  ? 415 SER B OG  1 
ATOM   7036  N  N   . ARG B 1 416 ? 148.227 164.888 155.920 1.00 66.81  ? 416 ARG B N   1 
ATOM   7037  C  CA  . ARG B 1 416 ? 148.370 166.315 156.166 1.00 66.81  ? 416 ARG B CA  1 
ATOM   7038  C  C   . ARG B 1 416 ? 149.800 166.730 156.461 1.00 66.81  ? 416 ARG B C   1 
ATOM   7039  O  O   . ARG B 1 416 ? 150.041 167.921 156.683 1.00 66.81  ? 416 ARG B O   1 
ATOM   7040  C  CB  . ARG B 1 416 ? 147.496 166.753 157.351 1.00 66.81  ? 416 ARG B CB  1 
ATOM   7041  C  CG  . ARG B 1 416 ? 146.004 166.615 157.145 1.00 66.81  ? 416 ARG B CG  1 
ATOM   7042  C  CD  . ARG B 1 416 ? 145.248 167.077 158.380 1.00 66.81  ? 416 ARG B CD  1 
ATOM   7043  N  NE  . ARG B 1 416 ? 143.812 166.846 158.264 1.00 66.81  ? 416 ARG B NE  1 
ATOM   7044  C  CZ  . ARG B 1 416 ? 142.956 167.719 157.745 1.00 66.81  ? 416 ARG B CZ  1 
ATOM   7045  N  NH1 . ARG B 1 416 ? 143.392 168.885 157.294 1.00 66.81  ? 416 ARG B NH1 1 
ATOM   7046  N  NH2 . ARG B 1 416 ? 141.665 167.427 157.677 1.00 66.81  ? 416 ARG B NH2 1 
ATOM   7047  N  N   . LEU B 1 417 ? 150.747 165.799 156.473 1.00 66.20  ? 417 LEU B N   1 
ATOM   7048  C  CA  . LEU B 1 417 ? 152.065 166.067 157.026 1.00 66.20  ? 417 LEU B CA  1 
ATOM   7049  C  C   . LEU B 1 417 ? 152.864 167.021 156.147 1.00 66.20  ? 417 LEU B C   1 
ATOM   7050  O  O   . LEU B 1 417 ? 152.607 167.173 154.951 1.00 66.20  ? 417 LEU B O   1 
ATOM   7051  C  CB  . LEU B 1 417 ? 152.842 164.764 157.199 1.00 66.20  ? 417 LEU B CB  1 
ATOM   7052  C  CG  . LEU B 1 417 ? 152.312 163.764 158.224 1.00 66.20  ? 417 LEU B CG  1 
ATOM   7053  C  CD1 . LEU B 1 417 ? 153.121 162.481 158.167 1.00 66.20  ? 417 LEU B CD1 1 
ATOM   7054  C  CD2 . LEU B 1 417 ? 152.345 164.361 159.620 1.00 66.20  ? 417 LEU B CD2 1 
ATOM   7055  N  N   . ILE B 1 418 ? 153.844 167.671 156.769 1.00 63.34  ? 418 ILE B N   1 
ATOM   7056  C  CA  . ILE B 1 418 ? 154.857 168.459 156.080 1.00 63.34  ? 418 ILE B CA  1 
ATOM   7057  C  C   . ILE B 1 418 ? 156.198 167.803 156.353 1.00 63.34  ? 418 ILE B C   1 
ATOM   7058  O  O   . ILE B 1 418 ? 156.503 167.471 157.504 1.00 63.34  ? 418 ILE B O   1 
ATOM   7059  C  CB  . ILE B 1 418 ? 154.868 169.920 156.558 1.00 63.34  ? 418 ILE B CB  1 
ATOM   7060  C  CG1 . ILE B 1 418 ? 153.484 170.539 156.417 1.00 63.34  ? 418 ILE B CG1 1 
ATOM   7061  C  CG2 . ILE B 1 418 ? 155.885 170.724 155.767 1.00 63.34  ? 418 ILE B CG2 1 
ATOM   7062  C  CD1 . ILE B 1 418 ? 152.998 170.553 155.017 1.00 63.34  ? 418 ILE B CD1 1 
ATOM   7063  N  N   . GLN B 1 419 ? 156.997 167.604 155.311 1.00 63.23  ? 419 GLN B N   1 
ATOM   7064  C  CA  . GLN B 1 419 ? 158.329 167.041 155.485 1.00 63.23  ? 419 GLN B CA  1 
ATOM   7065  C  C   . GLN B 1 419 ? 159.363 167.957 154.854 1.00 63.23  ? 419 GLN B C   1 
ATOM   7066  O  O   . GLN B 1 419 ? 159.079 168.633 153.860 1.00 63.23  ? 419 GLN B O   1 
ATOM   7067  C  CB  . GLN B 1 419 ? 158.421 165.631 154.908 1.00 63.23  ? 419 GLN B CB  1 
ATOM   7068  C  CG  . GLN B 1 419 ? 157.608 164.626 155.700 1.00 63.23  ? 419 GLN B CG  1 
ATOM   7069  C  CD  . GLN B 1 419 ? 157.750 163.220 155.179 1.00 63.23  ? 419 GLN B CD  1 
ATOM   7070  O  OE1 . GLN B 1 419 ? 158.429 162.982 154.187 1.00 63.23  ? 419 GLN B OE1 1 
ATOM   7071  N  NE2 . GLN B 1 419 ? 157.106 162.275 155.847 1.00 63.23  ? 419 GLN B NE2 1 
ATOM   7072  N  N   . CYS B 1 420 ? 160.558 167.968 155.434 1.00 68.47  ? 420 CYS B N   1 
ATOM   7073  C  CA  . CYS B 1 420 ? 161.591 168.956 155.141 1.00 68.47  ? 420 CYS B CA  1 
ATOM   7074  C  C   . CYS B 1 420 ? 162.922 168.238 154.959 1.00 68.47  ? 420 CYS B C   1 
ATOM   7075  O  O   . CYS B 1 420 ? 163.751 168.215 155.873 1.00 68.47  ? 420 CYS B O   1 
ATOM   7076  C  CB  . CYS B 1 420 ? 161.667 169.983 156.265 1.00 68.47  ? 420 CYS B CB  1 
ATOM   7077  S  SG  . CYS B 1 420 ? 162.903 171.276 156.063 1.00 68.47  ? 420 CYS B SG  1 
ATOM   7078  N  N   . PHE B 1 421 ? 163.129 167.652 153.785 1.00 70.06  ? 421 PHE B N   1 
ATOM   7079  C  CA  . PHE B 1 421 ? 164.399 167.019 153.443 1.00 70.06  ? 421 PHE B CA  1 
ATOM   7080  C  C   . PHE B 1 421 ? 165.391 168.138 153.153 1.00 70.06  ? 421 PHE B C   1 
ATOM   7081  O  O   . PHE B 1 421 ? 165.086 169.075 152.412 1.00 70.06  ? 421 PHE B O   1 
ATOM   7082  C  CB  . PHE B 1 421 ? 164.250 166.078 152.254 1.00 70.06  ? 421 PHE B CB  1 
ATOM   7083  C  CG  . PHE B 1 421 ? 165.497 165.307 151.942 1.00 70.06  ? 421 PHE B CG  1 
ATOM   7084  C  CD1 . PHE B 1 421 ? 165.844 164.196 152.690 1.00 70.06  ? 421 PHE B CD1 1 
ATOM   7085  C  CD2 . PHE B 1 421 ? 166.336 165.705 150.920 1.00 70.06  ? 421 PHE B CD2 1 
ATOM   7086  C  CE1 . PHE B 1 421 ? 166.994 163.488 152.412 1.00 70.06  ? 421 PHE B CE1 1 
ATOM   7087  C  CE2 . PHE B 1 421 ? 167.490 165.000 150.639 1.00 70.06  ? 421 PHE B CE2 1 
ATOM   7088  C  CZ  . PHE B 1 421 ? 167.819 163.891 151.386 1.00 70.06  ? 421 PHE B CZ  1 
ATOM   7089  N  N   . ASP B 1 422 ? 166.576 168.046 153.746 1.00 77.22  ? 422 ASP B N   1 
ATOM   7090  C  CA  . ASP B 1 422 ? 167.575 169.093 153.585 1.00 77.22  ? 422 ASP B CA  1 
ATOM   7091  C  C   . ASP B 1 422 ? 168.710 168.602 152.698 1.00 77.22  ? 422 ASP B C   1 
ATOM   7092  O  O   . ASP B 1 422 ? 169.608 167.892 153.157 1.00 77.22  ? 422 ASP B O   1 
ATOM   7093  C  CB  . ASP B 1 422 ? 168.110 169.523 154.949 1.00 77.22  ? 422 ASP B CB  1 
ATOM   7094  C  CG  . ASP B 1 422 ? 168.984 170.759 154.872 1.00 77.22  ? 422 ASP B CG  1 
ATOM   7095  O  OD1 . ASP B 1 422 ? 169.200 171.278 153.757 1.00 77.22  ? 422 ASP B OD1 1 
ATOM   7096  O  OD2 . ASP B 1 422 ? 169.458 171.215 155.932 1.00 77.22  ? 422 ASP B OD2 1 
ATOM   7097  N  N   . THR B 1 423 ? 168.680 168.997 151.427 1.00 74.73  ? 423 THR B N   1 
ATOM   7098  C  CA  . THR B 1 423 ? 169.634 168.523 150.433 1.00 74.73  ? 423 THR B CA  1 
ATOM   7099  C  C   . THR B 1 423 ? 171.023 169.138 150.577 1.00 74.73  ? 423 THR B C   1 
ATOM   7100  O  O   . THR B 1 423 ? 171.714 169.323 149.570 1.00 74.73  ? 423 THR B O   1 
ATOM   7101  C  CB  . THR B 1 423 ? 169.098 168.777 149.025 1.00 74.73  ? 423 THR B CB  1 
ATOM   7102  O  OG1 . THR B 1 423 ? 170.042 168.286 148.068 1.00 74.73  ? 423 THR B OG1 1 
ATOM   7103  C  CG2 . THR B 1 423 ? 168.865 170.249 148.783 1.00 74.73  ? 423 THR B CG2 1 
ATOM   7104  N  N   . GLU B 1 424 ? 171.453 169.445 151.799 1.00 82.96  ? 424 GLU B N   1 
ATOM   7105  C  CA  . GLU B 1 424 ? 172.819 169.879 152.061 1.00 82.96  ? 424 GLU B CA  1 
ATOM   7106  C  C   . GLU B 1 424 ? 173.483 169.036 153.142 1.00 82.96  ? 424 GLU B C   1 
ATOM   7107  O  O   . GLU B 1 424 ? 174.648 168.650 153.004 1.00 82.96  ? 424 GLU B O   1 
ATOM   7108  C  CB  . GLU B 1 424 ? 172.839 171.359 152.460 1.00 82.96  ? 424 GLU B CB  1 
ATOM   7109  C  CG  . GLU B 1 424 ? 174.234 171.932 152.657 1.00 82.96  ? 424 GLU B CG  1 
ATOM   7110  C  CD  . GLU B 1 424 ? 175.033 171.981 151.368 1.00 82.96  ? 424 GLU B CD  1 
ATOM   7111  O  OE1 . GLU B 1 424 ? 174.417 172.060 150.285 1.00 82.96  ? 424 GLU B OE1 1 
ATOM   7112  O  OE2 . GLU B 1 424 ? 176.280 171.940 151.438 1.00 82.96  ? 424 GLU B OE2 1 
ATOM   7113  N  N   . THR B 1 425 ? 172.758 168.739 154.217 1.00 83.76  ? 425 THR B N   1 
ATOM   7114  C  CA  . THR B 1 425 ? 173.221 167.832 155.256 1.00 83.76  ? 425 THR B CA  1 
ATOM   7115  C  C   . THR B 1 425 ? 172.489 166.498 155.237 1.00 83.76  ? 425 THR B C   1 
ATOM   7116  O  O   . THR B 1 425 ? 172.837 165.605 156.017 1.00 83.76  ? 425 THR B O   1 
ATOM   7117  C  CB  . THR B 1 425 ? 173.069 168.479 156.636 1.00 83.76  ? 425 THR B CB  1 
ATOM   7118  O  OG1 . THR B 1 425 ? 171.686 168.752 156.889 1.00 83.76  ? 425 THR B OG1 1 
ATOM   7119  C  CG2 . THR B 1 425 ? 173.855 169.778 156.703 1.00 83.76  ? 425 THR B CG2 1 
ATOM   7120  N  N   . ASP B 1 426 ? 171.487 166.346 154.369 1.00 82.76  ? 426 ASP B N   1 
ATOM   7121  C  CA  . ASP B 1 426 ? 170.733 165.103 154.213 1.00 82.76  ? 426 ASP B CA  1 
ATOM   7122  C  C   . ASP B 1 426 ? 170.103 164.673 155.538 1.00 82.76  ? 426 ASP B C   1 
ATOM   7123  O  O   . ASP B 1 426 ? 170.531 163.716 156.185 1.00 82.76  ? 426 ASP B O   1 
ATOM   7124  C  CB  . ASP B 1 426 ? 171.622 163.997 153.634 1.00 82.76  ? 426 ASP B CB  1 
ATOM   7125  C  CG  . ASP B 1 426 ? 172.008 164.258 152.192 1.00 82.76  ? 426 ASP B CG  1 
ATOM   7126  O  OD1 . ASP B 1 426 ? 171.213 164.893 151.467 1.00 82.76  ? 426 ASP B OD1 1 
ATOM   7127  O  OD2 . ASP B 1 426 ? 173.107 163.831 151.783 1.00 82.76  ? 426 ASP B OD2 1 
ATOM   7128  N  N   . LYS B 1 427 ? 169.065 165.405 155.933 1.00 82.18  ? 427 LYS B N   1 
ATOM   7129  C  CA  . LYS B 1 427 ? 168.373 165.127 157.182 1.00 82.18  ? 427 LYS B CA  1 
ATOM   7130  C  C   . LYS B 1 427 ? 166.947 165.643 157.084 1.00 82.18  ? 427 LYS B C   1 
ATOM   7131  O  O   . LYS B 1 427 ? 166.718 166.855 157.080 1.00 82.18  ? 427 LYS B O   1 
ATOM   7132  C  CB  . LYS B 1 427 ? 169.095 165.772 158.370 1.00 82.18  ? 427 LYS B CB  1 
ATOM   7133  C  CG  . LYS B 1 427 ? 168.545 165.374 159.728 1.00 82.18  ? 427 LYS B CG  1 
ATOM   7134  C  CD  . LYS B 1 427 ? 169.328 166.041 160.847 1.00 82.18  ? 427 LYS B CD  1 
ATOM   7135  C  CE  . LYS B 1 427 ? 170.736 165.477 160.944 1.00 82.18  ? 427 LYS B CE  1 
ATOM   7136  N  NZ  . LYS B 1 427 ? 170.741 164.050 161.368 1.00 82.18  ? 427 LYS B NZ  1 
ATOM   7137  N  N   . CYS B 1 428 ? 165.996 164.717 157.007 1.00 75.87  ? 428 CYS B N   1 
ATOM   7138  C  CA  . CYS B 1 428 ? 164.586 165.051 156.894 1.00 75.87  ? 428 CYS B CA  1 
ATOM   7139  C  C   . CYS B 1 428 ? 163.904 164.849 158.237 1.00 75.87  ? 428 CYS B C   1 
ATOM   7140  O  O   . CYS B 1 428 ? 164.302 163.994 159.031 1.00 75.87  ? 428 CYS B O   1 
ATOM   7141  C  CB  . CYS B 1 428 ? 163.891 164.201 155.828 1.00 75.87  ? 428 CYS B CB  1 
ATOM   7142  S  SG  . CYS B 1 428 ? 163.851 162.444 156.205 1.00 75.87  ? 428 CYS B SG  1 
ATOM   7143  N  N   . HIS B 1 429 ? 162.866 165.646 158.481 1.00 72.49  ? 429 HIS B N   1 
ATOM   7144  C  CA  . HIS B 1 429 ? 162.121 165.572 159.728 1.00 72.49  ? 429 HIS B CA  1 
ATOM   7145  C  C   . HIS B 1 429 ? 160.780 166.266 159.556 1.00 72.49  ? 429 HIS B C   1 
ATOM   7146  O  O   . HIS B 1 429 ? 160.686 167.352 158.979 1.00 72.49  ? 429 HIS B O   1 
ATOM   7147  C  CB  . HIS B 1 429 ? 162.915 166.180 160.890 1.00 72.49  ? 429 HIS B CB  1 
ATOM   7148  C  CG  . HIS B 1 429 ? 163.307 167.607 160.676 1.00 72.49  ? 429 HIS B CG  1 
ATOM   7149  N  ND1 . HIS B 1 429 ? 164.399 167.970 159.918 1.00 72.49  ? 429 HIS B ND1 1 
ATOM   7150  C  CD2 . HIS B 1 429 ? 162.765 168.761 161.131 1.00 72.49  ? 429 HIS B CD2 1 
ATOM   7151  C  CE1 . HIS B 1 429 ? 164.510 169.286 159.910 1.00 72.49  ? 429 HIS B CE1 1 
ATOM   7152  N  NE2 . HIS B 1 429 ? 163.530 169.790 160.639 1.00 72.49  ? 429 HIS B NE2 1 
ATOM   7153  N  N   . VAL B 1 430 ? 159.739 165.615 160.068 1.00 69.31  ? 430 VAL B N   1 
ATOM   7154  C  CA  . VAL B 1 430 ? 158.359 166.064 159.925 1.00 69.31  ? 430 VAL B CA  1 
ATOM   7155  C  C   . VAL B 1 430 ? 158.173 167.358 160.702 1.00 69.31  ? 430 VAL B C   1 
ATOM   7156  O  O   . VAL B 1 430 ? 158.614 167.470 161.852 1.00 69.31  ? 430 VAL B O   1 
ATOM   7157  C  CB  . VAL B 1 430 ? 157.375 164.988 160.417 1.00 69.31  ? 430 VAL B CB  1 
ATOM   7158  C  CG1 . VAL B 1 430 ? 155.948 165.501 160.349 1.00 69.31  ? 430 VAL B CG1 1 
ATOM   7159  C  CG2 . VAL B 1 430 ? 157.529 163.718 159.603 1.00 69.31  ? 430 VAL B CG2 1 
ATOM   7160  N  N   . LYS B 1 431 ? 157.518 168.333 160.080 1.00 67.70  ? 431 LYS B N   1 
ATOM   7161  C  CA  . LYS B 1 431 ? 157.187 169.562 160.782 1.00 67.70  ? 431 LYS B CA  1 
ATOM   7162  C  C   . LYS B 1 431 ? 156.011 169.319 161.726 1.00 67.70  ? 431 LYS B C   1 
ATOM   7163  O  O   . LYS B 1 431 ? 155.100 168.551 161.399 1.00 67.70  ? 431 LYS B O   1 
ATOM   7164  C  CB  . LYS B 1 431 ? 156.851 170.675 159.790 1.00 67.70  ? 431 LYS B CB  1 
ATOM   7165  C  CG  . LYS B 1 431 ? 157.998 171.043 158.863 1.00 67.70  ? 431 LYS B CG  1 
ATOM   7166  C  CD  . LYS B 1 431 ? 159.156 171.631 159.647 1.00 67.70  ? 431 LYS B CD  1 
ATOM   7167  C  CE  . LYS B 1 431 ? 160.284 172.074 158.734 1.00 67.70  ? 431 LYS B CE  1 
ATOM   7168  N  NZ  . LYS B 1 431 ? 161.452 172.600 159.495 1.00 67.70  ? 431 LYS B NZ  1 
ATOM   7169  N  N   . PRO B 1 432 ? 156.001 169.955 162.902 1.00 69.16  ? 432 PRO B N   1 
ATOM   7170  C  CA  . PRO B 1 432 ? 154.957 169.650 163.897 1.00 69.16  ? 432 PRO B CA  1 
ATOM   7171  C  C   . PRO B 1 432 ? 153.539 169.937 163.427 1.00 69.16  ? 432 PRO B C   1 
ATOM   7172  O  O   . PRO B 1 432 ? 152.635 169.134 163.693 1.00 69.16  ? 432 PRO B O   1 
ATOM   7173  C  CB  . PRO B 1 432 ? 155.345 170.543 165.084 1.00 69.16  ? 432 PRO B CB  1 
ATOM   7174  C  CG  . PRO B 1 432 ? 156.806 170.799 164.907 1.00 69.16  ? 432 PRO B CG  1 
ATOM   7175  C  CD  . PRO B 1 432 ? 157.014 170.884 163.429 1.00 69.16  ? 432 PRO B CD  1 
ATOM   7176  N  N   . TYR B 1 433 ? 153.312 171.054 162.746 1.00 65.24  ? 433 TYR B N   1 
ATOM   7177  C  CA  . TYR B 1 433 ? 151.980 171.448 162.316 1.00 65.24  ? 433 TYR B CA  1 
ATOM   7178  C  C   . TYR B 1 433 ? 151.558 170.681 161.061 1.00 65.24  ? 433 TYR B C   1 
ATOM   7179  O  O   . TYR B 1 433 ? 152.311 169.880 160.503 1.00 65.24  ? 433 TYR B O   1 
ATOM   7180  C  CB  . TYR B 1 433 ? 151.936 172.955 162.080 1.00 65.24  ? 433 TYR B CB  1 
ATOM   7181  C  CG  . TYR B 1 433 ? 152.986 173.439 161.107 1.00 65.24  ? 433 TYR B CG  1 
ATOM   7182  C  CD1 . TYR B 1 433 ? 154.248 173.813 161.551 1.00 65.24  ? 433 TYR B CD1 1 
ATOM   7183  C  CD2 . TYR B 1 433 ? 152.722 173.517 159.750 1.00 65.24  ? 433 TYR B CD2 1 
ATOM   7184  C  CE1 . TYR B 1 433 ? 155.214 174.249 160.674 1.00 65.24  ? 433 TYR B CE1 1 
ATOM   7185  C  CE2 . TYR B 1 433 ? 153.687 173.955 158.862 1.00 65.24  ? 433 TYR B CE2 1 
ATOM   7186  C  CZ  . TYR B 1 433 ? 154.930 174.321 159.331 1.00 65.24  ? 433 TYR B CZ  1 
ATOM   7187  O  OH  . TYR B 1 433 ? 155.899 174.759 158.459 1.00 65.24  ? 433 TYR B OH  1 
ATOM   7188  N  N   . VAL B 1 434 ? 150.322 170.934 160.620 1.00 64.78  ? 434 VAL B N   1 
ATOM   7189  C  CA  . VAL B 1 434 ? 149.735 170.247 159.477 1.00 64.78  ? 434 VAL B CA  1 
ATOM   7190  C  C   . VAL B 1 434 ? 149.060 171.260 158.562 1.00 64.78  ? 434 VAL B C   1 
ATOM   7191  O  O   . VAL B 1 434 ? 148.917 172.437 158.893 1.00 64.78  ? 434 VAL B O   1 
ATOM   7192  C  CB  . VAL B 1 434 ? 148.718 169.164 159.901 1.00 64.78  ? 434 VAL B CB  1 
ATOM   7193  C  CG1 . VAL B 1 434 ? 149.394 168.071 160.718 1.00 64.78  ? 434 VAL B CG1 1 
ATOM   7194  C  CG2 . VAL B 1 434 ? 147.563 169.790 160.672 1.00 64.78  ? 434 VAL B CG2 1 
ATOM   7195  N  N   . LEU B 1 435 ? 148.628 170.771 157.400 1.00 64.79  ? 435 LEU B N   1 
ATOM   7196  C  CA  . LEU B 1 435 ? 147.976 171.607 156.407 1.00 64.79  ? 435 LEU B CA  1 
ATOM   7197  C  C   . LEU B 1 435 ? 146.487 171.749 156.709 1.00 64.79  ? 435 LEU B C   1 
ATOM   7198  O  O   . LEU B 1 435 ? 145.925 170.979 157.490 1.00 64.79  ? 435 LEU B O   1 
ATOM   7199  C  CB  . LEU B 1 435 ? 148.164 171.015 155.014 1.00 64.79  ? 435 LEU B CB  1 
ATOM   7200  C  CG  . LEU B 1 435 ? 149.577 171.037 154.444 1.00 64.79  ? 435 LEU B CG  1 
ATOM   7201  C  CD1 . LEU B 1 435 ? 149.623 170.260 153.149 1.00 64.79  ? 435 LEU B CD1 1 
ATOM   7202  C  CD2 . LEU B 1 435 ? 150.038 172.468 154.227 1.00 64.79  ? 435 LEU B CD2 1 
ATOM   7203  N  N   . PRO B 1 436 ? 145.824 172.739 156.105 1.00 65.54  ? 436 PRO B N   1 
ATOM   7204  C  CA  . PRO B 1 436 ? 144.363 172.817 156.248 1.00 65.54  ? 436 PRO B CA  1 
ATOM   7205  C  C   . PRO B 1 436 ? 143.646 171.638 155.620 1.00 65.54  ? 436 PRO B C   1 
ATOM   7206  O  O   . PRO B 1 436 ? 142.989 170.867 156.330 1.00 65.54  ? 436 PRO B O   1 
ATOM   7207  C  CB  . PRO B 1 436 ? 144.015 174.133 155.538 1.00 65.54  ? 436 PRO B CB  1 
ATOM   7208  C  CG  . PRO B 1 436 ? 145.278 174.922 155.549 1.00 65.54  ? 436 PRO B CG  1 
ATOM   7209  C  CD  . PRO B 1 436 ? 146.364 173.910 155.395 1.00 65.54  ? 436 PRO B CD  1 
ATOM   7210  N  N   . PHE B 1 437 ? 143.750 171.478 154.308 1.00 69.95  ? 437 PHE B N   1 
ATOM   7211  C  CA  . PHE B 1 437 ? 143.206 170.346 153.573 1.00 69.95  ? 437 PHE B CA  1 
ATOM   7212  C  C   . PHE B 1 437 ? 144.193 169.183 153.605 1.00 69.95  ? 437 PHE B C   1 
ATOM   7213  O  O   . PHE B 1 437 ? 145.213 169.219 154.297 1.00 69.95  ? 437 PHE B O   1 
ATOM   7214  C  CB  . PHE B 1 437 ? 142.871 170.753 152.137 1.00 69.95  ? 437 PHE B CB  1 
ATOM   7215  C  CG  . PHE B 1 437 ? 143.985 171.481 151.447 1.00 69.95  ? 437 PHE B CG  1 
ATOM   7216  C  CD1 . PHE B 1 437 ? 143.998 172.863 151.416 1.00 69.95  ? 437 PHE B CD1 1 
ATOM   7217  C  CD2 . PHE B 1 437 ? 145.035 170.795 150.870 1.00 69.95  ? 437 PHE B CD2 1 
ATOM   7218  C  CE1 . PHE B 1 437 ? 145.019 173.545 150.798 1.00 69.95  ? 437 PHE B CE1 1 
ATOM   7219  C  CE2 . PHE B 1 437 ? 146.063 171.477 150.252 1.00 69.95  ? 437 PHE B CE2 1 
ATOM   7220  C  CZ  . PHE B 1 437 ? 146.050 172.853 150.216 1.00 69.95  ? 437 PHE B CZ  1 
ATOM   7221  N  N   . ALA B 1 438 ? 143.877 168.142 152.838 1.00 73.43  ? 438 ALA B N   1 
ATOM   7222  C  CA  . ALA B 1 438 ? 144.671 166.924 152.817 1.00 73.43  ? 438 ALA B CA  1 
ATOM   7223  C  C   . ALA B 1 438 ? 144.345 166.124 151.567 1.00 73.43  ? 438 ALA B C   1 
ATOM   7224  O  O   . ALA B 1 438 ? 143.242 166.203 151.023 1.00 73.43  ? 438 ALA B O   1 
ATOM   7225  C  CB  . ALA B 1 438 ? 144.419 166.066 154.061 1.00 73.43  ? 438 ALA B CB  1 
ATOM   7226  N  N   . GLY B 1 439 ? 145.320 165.347 151.120 1.00 70.41  ? 439 GLY B N   1 
ATOM   7227  C  CA  . GLY B 1 439 ? 145.138 164.438 150.012 1.00 70.41  ? 439 GLY B CA  1 
ATOM   7228  C  C   . GLY B 1 439 ? 146.001 164.783 148.816 1.00 70.41  ? 439 GLY B C   1 
ATOM   7229  O  O   . GLY B 1 439 ? 147.191 165.090 148.928 1.00 70.41  ? 439 GLY B O   1 
ATOM   7230  N  N   . ARG B 1 440 ? 145.379 164.718 147.643 1.00 73.29  ? 440 ARG B N   1 
ATOM   7231  C  CA  . ARG B 1 440 ? 146.073 165.011 146.399 1.00 73.29  ? 440 ARG B CA  1 
ATOM   7232  C  C   . ARG B 1 440 ? 146.138 166.515 146.167 1.00 73.29  ? 440 ARG B C   1 
ATOM   7233  O  O   . ARG B 1 440 ? 145.114 167.191 146.039 1.00 73.29  ? 440 ARG B O   1 
ATOM   7234  C  CB  . ARG B 1 440 ? 145.370 164.318 145.231 1.00 73.29  ? 440 ARG B CB  1 
ATOM   7235  C  CG  . ARG B 1 440 ? 146.005 164.534 143.865 1.00 73.29  ? 440 ARG B CG  1 
ATOM   7236  C  CD  . ARG B 1 440 ? 145.289 165.623 143.078 1.00 73.29  ? 440 ARG B CD  1 
ATOM   7237  N  NE  . ARG B 1 440 ? 145.830 165.774 141.731 1.00 73.29  ? 440 ARG B NE  1 
ATOM   7238  C  CZ  . ARG B 1 440 ? 145.436 165.053 140.687 1.00 73.29  ? 440 ARG B CZ  1 
ATOM   7239  N  NH1 . ARG B 1 440 ? 144.499 164.126 140.835 1.00 73.29  ? 440 ARG B NH1 1 
ATOM   7240  N  NH2 . ARG B 1 440 ? 145.979 165.255 139.495 1.00 73.29  ? 440 ARG B NH2 1 
ATOM   7241  N  N   . MET B 1 441 ? 147.360 167.039 146.105 1.00 66.38  ? 441 MET B N   1 
ATOM   7242  C  CA  . MET B 1 441 ? 147.560 168.473 145.966 1.00 66.38  ? 441 MET B CA  1 
ATOM   7243  C  C   . MET B 1 441 ? 148.718 168.741 145.017 1.00 66.38  ? 441 MET B C   1 
ATOM   7244  O  O   . MET B 1 441 ? 149.588 167.890 144.816 1.00 66.38  ? 441 MET B O   1 
ATOM   7245  C  CB  . MET B 1 441 ? 147.820 169.133 147.323 1.00 66.38  ? 441 MET B CB  1 
ATOM   7246  C  CG  . MET B 1 441 ? 149.081 168.670 148.014 1.00 66.38  ? 441 MET B CG  1 
ATOM   7247  S  SD  . MET B 1 441 ? 149.216 169.361 149.669 1.00 66.38  ? 441 MET B SD  1 
ATOM   7248  C  CE  . MET B 1 441 ? 147.952 168.423 150.518 1.00 66.38  ? 441 MET B CE  1 
ATOM   7249  N  N   . HIS B 1 442 ? 148.712 169.936 144.436 1.00 63.38  ? 442 HIS B N   1 
ATOM   7250  C  CA  . HIS B 1 442 ? 149.750 170.395 143.525 1.00 63.38  ? 442 HIS B CA  1 
ATOM   7251  C  C   . HIS B 1 442 ? 150.218 171.761 144.000 1.00 63.38  ? 442 HIS B C   1 
ATOM   7252  O  O   . HIS B 1 442 ? 149.393 172.638 144.281 1.00 63.38  ? 442 HIS B O   1 
ATOM   7253  C  CB  . HIS B 1 442 ? 149.219 170.461 142.089 1.00 63.38  ? 442 HIS B CB  1 
ATOM   7254  C  CG  . HIS B 1 442 ? 150.283 170.643 141.051 1.00 63.38  ? 442 HIS B CG  1 
ATOM   7255  N  ND1 . HIS B 1 442 ? 150.734 171.882 140.652 1.00 63.38  ? 442 HIS B ND1 1 
ATOM   7256  C  CD2 . HIS B 1 442 ? 150.976 169.737 140.320 1.00 63.38  ? 442 HIS B CD2 1 
ATOM   7257  C  CE1 . HIS B 1 442 ? 151.664 171.732 139.726 1.00 63.38  ? 442 HIS B CE1 1 
ATOM   7258  N  NE2 . HIS B 1 442 ? 151.830 170.440 139.507 1.00 63.38  ? 442 HIS B NE2 1 
ATOM   7259  N  N   . ALA B 1 443 ? 151.534 171.938 144.105 1.00 54.74  ? 443 ALA B N   1 
ATOM   7260  C  CA  . ALA B 1 443 ? 152.117 173.143 144.677 1.00 54.74  ? 443 ALA B CA  1 
ATOM   7261  C  C   . ALA B 1 443 ? 153.247 173.653 143.798 1.00 54.74  ? 443 ALA B C   1 
ATOM   7262  O  O   . ALA B 1 443 ? 153.921 172.870 143.123 1.00 54.74  ? 443 ALA B O   1 
ATOM   7263  C  CB  . ALA B 1 443 ? 152.646 172.885 146.089 1.00 54.74  ? 443 ALA B CB  1 
ATOM   7264  N  N   . ALA B 1 444 ? 153.455 174.967 143.821 1.00 52.17  ? 444 ALA B N   1 
ATOM   7265  C  CA  . ALA B 1 444 ? 154.527 175.601 143.067 1.00 52.17  ? 444 ALA B CA  1 
ATOM   7266  C  C   . ALA B 1 444 ? 155.175 176.678 143.920 1.00 52.17  ? 444 ALA B C   1 
ATOM   7267  O  O   . ALA B 1 444 ? 154.491 177.369 144.681 1.00 52.17  ? 444 ALA B O   1 
ATOM   7268  C  CB  . ALA B 1 444 ? 154.009 176.206 141.761 1.00 52.17  ? 444 ALA B CB  1 
ATOM   7269  N  N   . VAL B 1 445 ? 156.489 176.812 143.789 1.00 54.68  ? 445 VAL B N   1 
ATOM   7270  C  CA  . VAL B 1 445 ? 157.244 177.806 144.541 1.00 54.68  ? 445 VAL B CA  1 
ATOM   7271  C  C   . VAL B 1 445 ? 157.183 179.132 143.799 1.00 54.68  ? 445 VAL B C   1 
ATOM   7272  O  O   . VAL B 1 445 ? 157.297 179.175 142.569 1.00 54.68  ? 445 VAL B O   1 
ATOM   7273  C  CB  . VAL B 1 445 ? 158.696 177.344 144.739 1.00 54.68  ? 445 VAL B CB  1 
ATOM   7274  C  CG1 . VAL B 1 445 ? 159.503 178.397 145.478 1.00 54.68  ? 445 VAL B CG1 1 
ATOM   7275  C  CG2 . VAL B 1 445 ? 158.732 176.028 145.478 1.00 54.68  ? 445 VAL B CG2 1 
ATOM   7276  N  N   . HIS B 1 446 ? 157.002 180.220 144.542 1.00 56.16  ? 446 HIS B N   1 
ATOM   7277  C  CA  . HIS B 1 446 ? 156.917 181.549 143.955 1.00 56.16  ? 446 HIS B CA  1 
ATOM   7278  C  C   . HIS B 1 446 ? 157.564 182.556 144.890 1.00 56.16  ? 446 HIS B C   1 
ATOM   7279  O  O   . HIS B 1 446 ? 157.108 182.731 146.023 1.00 56.16  ? 446 HIS B O   1 
ATOM   7280  C  CB  . HIS B 1 446 ? 155.464 181.935 143.680 1.00 56.16  ? 446 HIS B CB  1 
ATOM   7281  C  CG  . HIS B 1 446 ? 155.313 183.218 142.927 1.00 56.16  ? 446 HIS B CG  1 
ATOM   7282  N  ND1 . HIS B 1 446 ? 155.221 184.441 143.553 1.00 56.16  ? 446 HIS B ND1 1 
ATOM   7283  C  CD2 . HIS B 1 446 ? 155.250 183.469 141.599 1.00 56.16  ? 446 HIS B CD2 1 
ATOM   7284  C  CE1 . HIS B 1 446 ? 155.097 185.390 142.643 1.00 56.16  ? 446 HIS B CE1 1 
ATOM   7285  N  NE2 . HIS B 1 446 ? 155.113 184.827 141.449 1.00 56.16  ? 446 HIS B NE2 1 
ATOM   7286  N  N   . LYS B 1 447 ? 158.618 183.217 144.406 1.00 52.58  ? 447 LYS B N   1 
ATOM   7287  C  CA  . LYS B 1 447 ? 159.386 184.187 145.181 1.00 52.58  ? 447 LYS B CA  1 
ATOM   7288  C  C   . LYS B 1 447 ? 160.015 183.538 146.406 1.00 52.58  ? 447 LYS B C   1 
ATOM   7289  O  O   . LYS B 1 447 ? 161.233 183.349 146.461 1.00 52.58  ? 447 LYS B O   1 
ATOM   7290  C  CB  . LYS B 1 447 ? 158.511 185.370 145.603 1.00 52.58  ? 447 LYS B CB  1 
ATOM   7291  C  CG  . LYS B 1 447 ? 157.943 186.184 144.454 1.00 52.58  ? 447 LYS B CG  1 
ATOM   7292  C  CD  . LYS B 1 447 ? 159.025 186.955 143.725 1.00 52.58  ? 447 LYS B CD  1 
ATOM   7293  C  CE  . LYS B 1 447 ? 158.430 187.850 142.655 1.00 52.58  ? 447 LYS B CE  1 
ATOM   7294  N  NZ  . LYS B 1 447 ? 159.484 188.580 141.899 1.00 52.58  ? 447 LYS B NZ  1 
ATOM   7295  N  N   . ASP B 1 448 ? 159.190 183.183 147.387 1.00 55.74  ? 448 ASP B N   1 
ATOM   7296  C  CA  . ASP B 1 448 ? 159.689 182.688 148.662 1.00 55.74  ? 448 ASP B CA  1 
ATOM   7297  C  C   . ASP B 1 448 ? 158.649 181.777 149.303 1.00 55.74  ? 448 ASP B C   1 
ATOM   7298  O  O   . ASP B 1 448 ? 158.900 181.157 150.340 1.00 55.74  ? 448 ASP B O   1 
ATOM   7299  C  CB  . ASP B 1 448 ? 160.023 183.873 149.572 1.00 55.74  ? 448 ASP B CB  1 
ATOM   7300  C  CG  . ASP B 1 448 ? 160.859 183.483 150.771 1.00 55.74  ? 448 ASP B CG  1 
ATOM   7301  O  OD1 . ASP B 1 448 ? 161.225 182.298 150.896 1.00 55.74  ? 448 ASP B OD1 1 
ATOM   7302  O  OD2 . ASP B 1 448 ? 161.147 184.372 151.599 1.00 55.74  ? 448 ASP B OD2 1 
ATOM   7303  N  N   . LEU B 1 449 ? 157.481 181.679 148.677 1.00 50.88  ? 449 LEU B N   1 
ATOM   7304  C  CA  . LEU B 1 449 ? 156.331 181.017 149.265 1.00 50.88  ? 449 LEU B CA  1 
ATOM   7305  C  C   . LEU B 1 449 ? 155.973 179.771 148.461 1.00 50.88  ? 449 LEU B C   1 
ATOM   7306  O  O   . LEU B 1 449 ? 156.462 179.556 147.348 1.00 50.88  ? 449 LEU B O   1 
ATOM   7307  C  CB  . LEU B 1 449 ? 155.155 181.986 149.324 1.00 50.88  ? 449 LEU B CB  1 
ATOM   7308  C  CG  . LEU B 1 449 ? 155.398 183.288 150.084 1.00 50.88  ? 449 LEU B CG  1 
ATOM   7309  C  CD1 . LEU B 1 449 ? 154.189 184.187 149.973 1.00 50.88  ? 449 LEU B CD1 1 
ATOM   7310  C  CD2 . LEU B 1 449 ? 155.738 183.019 151.527 1.00 50.88  ? 449 LEU B CD2 1 
ATOM   7311  N  N   . VAL B 1 450 ? 155.088 178.946 149.020 1.00 50.51  ? 450 VAL B N   1 
ATOM   7312  C  CA  . VAL B 1 450 ? 154.659 177.703 148.388 1.00 50.51  ? 450 VAL B CA  1 
ATOM   7313  C  C   . VAL B 1 450 ? 153.152 177.757 148.186 1.00 50.51  ? 450 VAL B C   1 
ATOM   7314  O  O   . VAL B 1 450 ? 152.389 177.589 149.144 1.00 50.51  ? 450 VAL B O   1 
ATOM   7315  C  CB  . VAL B 1 450 ? 155.038 176.473 149.227 1.00 50.51  ? 450 VAL B CB  1 
ATOM   7316  C  CG1 . VAL B 1 450 ? 154.531 175.208 148.565 1.00 50.51  ? 450 VAL B CG1 1 
ATOM   7317  C  CG2 . VAL B 1 450 ? 156.532 176.412 149.424 1.00 50.51  ? 450 VAL B CG2 1 
ATOM   7318  N  N   . PHE B 1 451 ? 152.721 177.970 146.947 1.00 52.81  ? 451 PHE B N   1 
ATOM   7319  C  CA  . PHE B 1 451 ? 151.303 178.026 146.611 1.00 52.81  ? 451 PHE B CA  1 
ATOM   7320  C  C   . PHE B 1 451 ? 150.787 176.612 146.382 1.00 52.81  ? 451 PHE B C   1 
ATOM   7321  O  O   . PHE B 1 451 ? 151.319 175.883 145.539 1.00 52.81  ? 451 PHE B O   1 
ATOM   7322  C  CB  . PHE B 1 451 ? 151.079 178.902 145.382 1.00 52.81  ? 451 PHE B CB  1 
ATOM   7323  C  CG  . PHE B 1 451 ? 151.268 180.364 145.647 1.00 52.81  ? 451 PHE B CG  1 
ATOM   7324  C  CD1 . PHE B 1 451 ? 150.216 181.135 146.101 1.00 52.81  ? 451 PHE B CD1 1 
ATOM   7325  C  CD2 . PHE B 1 451 ? 152.505 180.958 145.487 1.00 52.81  ? 451 PHE B CD2 1 
ATOM   7326  C  CE1 . PHE B 1 451 ? 150.381 182.475 146.353 1.00 52.81  ? 451 PHE B CE1 1 
ATOM   7327  C  CE2 . PHE B 1 451 ? 152.679 182.300 145.749 1.00 52.81  ? 451 PHE B CE2 1 
ATOM   7328  C  CZ  . PHE B 1 451 ? 151.614 183.058 146.181 1.00 52.81  ? 451 PHE B CZ  1 
ATOM   7329  N  N   . ILE B 1 452 ? 149.753 176.229 147.129 1.00 57.42  ? 452 ILE B N   1 
ATOM   7330  C  CA  . ILE B 1 452 ? 149.250 174.860 147.151 1.00 57.42  ? 452 ILE B CA  1 
ATOM   7331  C  C   . ILE B 1 452 ? 147.775 174.877 146.775 1.00 57.42  ? 452 ILE B C   1 
ATOM   7332  O  O   . ILE B 1 452 ? 147.024 175.748 147.232 1.00 57.42  ? 452 ILE B O   1 
ATOM   7333  C  CB  . ILE B 1 452 ? 149.442 174.211 148.533 1.00 57.42  ? 452 ILE B CB  1 
ATOM   7334  C  CG1 . ILE B 1 452 ? 150.900 174.279 148.972 1.00 57.42  ? 452 ILE B CG1 1 
ATOM   7335  C  CG2 . ILE B 1 452 ? 149.034 172.760 148.496 1.00 57.42  ? 452 ILE B CG2 1 
ATOM   7336  C  CD1 . ILE B 1 452 ? 151.097 173.924 150.424 1.00 57.42  ? 452 ILE B CD1 1 
ATOM   7337  N  N   . VAL B 1 453 ? 147.361 173.910 145.955 1.00 66.63  ? 453 VAL B N   1 
ATOM   7338  C  CA  . VAL B 1 453 ? 145.967 173.727 145.566 1.00 66.63  ? 453 VAL B CA  1 
ATOM   7339  C  C   . VAL B 1 453 ? 145.613 172.256 145.720 1.00 66.63  ? 453 VAL B C   1 
ATOM   7340  O  O   . VAL B 1 453 ? 146.438 171.383 145.435 1.00 66.63  ? 453 VAL B O   1 
ATOM   7341  C  CB  . VAL B 1 453 ? 145.713 174.189 144.116 1.00 66.63  ? 453 VAL B CB  1 
ATOM   7342  C  CG1 . VAL B 1 453 ? 144.295 173.882 143.696 1.00 66.63  ? 453 VAL B CG1 1 
ATOM   7343  C  CG2 . VAL B 1 453 ? 145.960 175.657 143.995 1.00 66.63  ? 453 VAL B CG2 1 
ATOM   7344  N  N   . ALA B 1 454 ? 144.388 171.974 146.165 1.00 76.22  ? 454 ALA B N   1 
ATOM   7345  C  CA  . ALA B 1 454 ? 143.948 170.587 146.260 1.00 76.22  ? 454 ALA B CA  1 
ATOM   7346  C  C   . ALA B 1 454 ? 142.437 170.443 146.148 1.00 76.22  ? 454 ALA B C   1 
ATOM   7347  O  O   . ALA B 1 454 ? 141.883 170.415 145.044 1.00 76.22  ? 454 ALA B O   1 
ATOM   7348  C  CB  . ALA B 1 454 ? 144.419 169.964 147.573 1.00 76.22  ? 454 ALA B CB  1 
ATOM   7349  N  N   . GLU B 1 455 ? 141.771 170.346 147.295 1.00 86.56  ? 455 GLU B N   1 
ATOM   7350  C  CA  . GLU B 1 455 ? 140.352 170.035 147.347 1.00 86.56  ? 455 GLU B CA  1 
ATOM   7351  C  C   . GLU B 1 455 ? 139.522 171.136 146.696 1.00 86.56  ? 455 GLU B C   1 
ATOM   7352  O  O   . GLU B 1 455 ? 138.921 171.982 147.364 1.00 86.56  ? 455 GLU B O   1 
ATOM   7353  C  CB  . GLU B 1 455 ? 139.907 169.837 148.795 1.00 86.56  ? 455 GLU B CB  1 
ATOM   7354  C  CG  . GLU B 1 455 ? 140.527 168.627 149.470 1.00 86.56  ? 455 GLU B CG  1 
ATOM   7355  C  CD  . GLU B 1 455 ? 140.129 168.509 150.929 1.00 86.56  ? 455 GLU B CD  1 
ATOM   7356  O  OE1 . GLU B 1 455 ? 139.466 169.434 151.444 1.00 86.56  ? 455 GLU B OE1 1 
ATOM   7357  O  OE2 . GLU B 1 455 ? 140.486 167.494 151.564 1.00 86.56  ? 455 GLU B OE2 1 
ATOM   7358  N  N   . GLY B 1 456 ? 139.492 171.112 145.368 1.00 85.51  ? 456 GLY B N   1 
ATOM   7359  C  CA  . GLY B 1 456 ? 138.669 172.041 144.623 1.00 85.51  ? 456 GLY B CA  1 
ATOM   7360  C  C   . GLY B 1 456 ? 139.260 173.428 144.494 1.00 85.51  ? 456 GLY B C   1 
ATOM   7361  O  O   . GLY B 1 456 ? 140.290 173.612 143.840 1.00 85.51  ? 456 GLY B O   1 
ATOM   7362  N  N   . ASP B 1 457 ? 138.622 174.411 145.127 1.00 90.54  ? 457 ASP B N   1 
ATOM   7363  C  CA  . ASP B 1 457 ? 138.957 175.810 144.894 1.00 90.54  ? 457 ASP B CA  1 
ATOM   7364  C  C   . ASP B 1 457 ? 139.390 176.544 146.160 1.00 90.54  ? 457 ASP B C   1 
ATOM   7365  O  O   . ASP B 1 457 ? 138.596 177.270 146.768 1.00 90.54  ? 457 ASP B O   1 
ATOM   7366  C  CB  . ASP B 1 457 ? 137.765 176.514 144.239 1.00 90.54  ? 457 ASP B CB  1 
ATOM   7367  C  CG  . ASP B 1 457 ? 136.478 176.341 145.026 1.00 90.54  ? 457 ASP B CG  1 
ATOM   7368  O  OD1 . ASP B 1 457 ? 136.492 175.621 146.046 1.00 90.54  ? 457 ASP B OD1 1 
ATOM   7369  O  OD2 . ASP B 1 457 ? 135.450 176.923 144.623 1.00 90.54  ? 457 ASP B OD2 1 
ATOM   7370  N  N   . SER B 1 458 ? 140.656 176.376 146.554 1.00 82.85  ? 458 SER B N   1 
ATOM   7371  C  CA  . SER B 1 458 ? 141.208 177.108 147.695 1.00 82.85  ? 458 SER B CA  1 
ATOM   7372  C  C   . SER B 1 458 ? 142.718 176.883 147.696 1.00 82.85  ? 458 SER B C   1 
ATOM   7373  O  O   . SER B 1 458 ? 143.183 175.828 148.135 1.00 82.85  ? 458 SER B O   1 
ATOM   7374  C  CB  . SER B 1 458 ? 140.583 176.654 149.003 1.00 82.85  ? 458 SER B CB  1 
ATOM   7375  O  OG  . SER B 1 458 ? 140.942 175.315 149.295 1.00 82.85  ? 458 SER B OG  1 
ATOM   7376  N  N   . LEU B 1 459 ? 143.466 177.868 147.209 1.00 70.02  ? 459 LEU B N   1 
ATOM   7377  C  CA  . LEU B 1 459 ? 144.918 177.796 147.239 1.00 70.02  ? 459 LEU B CA  1 
ATOM   7378  C  C   . LEU B 1 459 ? 145.433 178.486 148.492 1.00 70.02  ? 459 LEU B C   1 
ATOM   7379  O  O   . LEU B 1 459 ? 145.004 179.597 148.818 1.00 70.02  ? 459 LEU B O   1 
ATOM   7380  C  CB  . LEU B 1 459 ? 145.540 178.424 145.989 1.00 70.02  ? 459 LEU B CB  1 
ATOM   7381  C  CG  . LEU B 1 459 ? 145.438 179.900 145.614 1.00 70.02  ? 459 LEU B CG  1 
ATOM   7382  C  CD1 . LEU B 1 459 ? 146.534 180.712 146.275 1.00 70.02  ? 459 LEU B CD1 1 
ATOM   7383  C  CD2 . LEU B 1 459 ? 145.542 180.031 144.112 1.00 70.02  ? 459 LEU B CD2 1 
ATOM   7384  N  N   . VAL B 1 460 ? 146.339 177.822 149.196 1.00 63.52  ? 460 VAL B N   1 
ATOM   7385  C  CA  . VAL B 1 460 ? 146.968 178.403 150.366 1.00 63.52  ? 460 VAL B CA  1 
ATOM   7386  C  C   . VAL B 1 460 ? 148.421 178.697 150.027 1.00 63.52  ? 460 VAL B C   1 
ATOM   7387  O  O   . VAL B 1 460 ? 149.125 177.884 149.426 1.00 63.52  ? 460 VAL B O   1 
ATOM   7388  C  CB  . VAL B 1 460 ? 146.854 177.488 151.610 1.00 63.52  ? 460 VAL B CB  1 
ATOM   7389  C  CG1 . VAL B 1 460 ? 145.399 177.297 151.994 1.00 63.52  ? 460 VAL B CG1 1 
ATOM   7390  C  CG2 . VAL B 1 460 ? 147.518 176.148 151.364 1.00 63.52  ? 460 VAL B CG2 1 
ATOM   7391  N  N   . CYS B 1 461 ? 148.877 179.893 150.381 1.00 59.85  ? 461 CYS B N   1 
ATOM   7392  C  CA  . CYS B 1 461 ? 150.287 180.236 150.248 1.00 59.85  ? 461 CYS B CA  1 
ATOM   7393  C  C   . CYS B 1 461 ? 150.936 179.951 151.595 1.00 59.85  ? 461 CYS B C   1 
ATOM   7394  O  O   . CYS B 1 461 ? 150.468 180.432 152.636 1.00 59.85  ? 461 CYS B O   1 
ATOM   7395  C  CB  . CYS B 1 461 ? 150.497 181.680 149.790 1.00 59.85  ? 461 CYS B CB  1 
ATOM   7396  S  SG  . CYS B 1 461 ? 149.999 182.965 150.925 1.00 59.85  ? 461 CYS B SG  1 
ATOM   7397  N  N   . TYR B 1 462 ? 151.974 179.123 151.557 1.00 55.67  ? 462 TYR B N   1 
ATOM   7398  C  CA  . TYR B 1 462 ? 152.667 178.612 152.728 1.00 55.67  ? 462 TYR B CA  1 
ATOM   7399  C  C   . TYR B 1 462 ? 154.024 179.279 152.866 1.00 55.67  ? 462 TYR B C   1 
ATOM   7400  O  O   . TYR B 1 462 ? 154.821 179.302 151.921 1.00 55.67  ? 462 TYR B O   1 
ATOM   7401  C  CB  . TYR B 1 462 ? 152.816 177.093 152.605 1.00 55.67  ? 462 TYR B CB  1 
ATOM   7402  C  CG  . TYR B 1 462 ? 153.788 176.438 153.567 1.00 55.67  ? 462 TYR B CG  1 
ATOM   7403  C  CD1 . TYR B 1 462 ? 153.545 176.425 154.937 1.00 55.67  ? 462 TYR B CD1 1 
ATOM   7404  C  CD2 . TYR B 1 462 ? 154.926 175.791 153.100 1.00 55.67  ? 462 TYR B CD2 1 
ATOM   7405  C  CE1 . TYR B 1 462 ? 154.406 175.818 155.814 1.00 55.67  ? 462 TYR B CE1 1 
ATOM   7406  C  CE2 . TYR B 1 462 ? 155.797 175.171 153.981 1.00 55.67  ? 462 TYR B CE2 1 
ATOM   7407  C  CZ  . TYR B 1 462 ? 155.528 175.192 155.330 1.00 55.67  ? 462 TYR B CZ  1 
ATOM   7408  O  OH  . TYR B 1 462 ? 156.388 174.582 156.202 1.00 55.67  ? 462 TYR B OH  1 
ATOM   7409  N  N   . ASN B 1 463 ? 154.261 179.873 154.031 1.00 56.33  ? 463 ASN B N   1 
ATOM   7410  C  CA  . ASN B 1 463 ? 155.541 180.518 154.314 1.00 56.33  ? 463 ASN B CA  1 
ATOM   7411  C  C   . ASN B 1 463 ? 156.336 179.615 155.245 1.00 56.33  ? 463 ASN B C   1 
ATOM   7412  O  O   . ASN B 1 463 ? 156.050 179.559 156.454 1.00 56.33  ? 463 ASN B O   1 
ATOM   7413  C  CB  . ASN B 1 463 ? 155.343 181.902 154.927 1.00 56.33  ? 463 ASN B CB  1 
ATOM   7414  C  CG  . ASN B 1 463 ? 156.600 182.741 154.878 1.00 56.33  ? 463 ASN B CG  1 
ATOM   7415  O  OD1 . ASN B 1 463 ? 157.646 182.284 154.425 1.00 56.33  ? 463 ASN B OD1 1 
ATOM   7416  N  ND2 . ASN B 1 463 ? 156.500 183.979 155.328 1.00 56.33  ? 463 ASN B ND2 1 
ATOM   7417  N  N   . PRO B 1 464 ? 157.325 178.876 154.737 1.00 57.91  ? 464 PRO B N   1 
ATOM   7418  C  CA  . PRO B 1 464 ? 158.030 177.915 155.599 1.00 57.91  ? 464 PRO B CA  1 
ATOM   7419  C  C   . PRO B 1 464 ? 158.911 178.563 156.650 1.00 57.91  ? 464 PRO B C   1 
ATOM   7420  O  O   . PRO B 1 464 ? 159.264 177.905 157.636 1.00 57.91  ? 464 PRO B O   1 
ATOM   7421  C  CB  . PRO B 1 464 ? 158.853 177.094 154.598 1.00 57.91  ? 464 PRO B CB  1 
ATOM   7422  C  CG  . PRO B 1 464 ? 159.049 178.007 153.442 1.00 57.91  ? 464 PRO B CG  1 
ATOM   7423  C  CD  . PRO B 1 464 ? 157.803 178.830 153.345 1.00 57.91  ? 464 PRO B CD  1 
ATOM   7424  N  N   . LEU B 1 465 ? 159.279 179.833 156.477 1.00 61.63  ? 465 LEU B N   1 
ATOM   7425  C  CA  . LEU B 1 465 ? 160.126 180.486 157.470 1.00 61.63  ? 465 LEU B CA  1 
ATOM   7426  C  C   . LEU B 1 465 ? 159.316 180.919 158.684 1.00 61.63  ? 465 LEU B C   1 
ATOM   7427  O  O   . LEU B 1 465 ? 159.749 180.732 159.826 1.00 61.63  ? 465 LEU B O   1 
ATOM   7428  C  CB  . LEU B 1 465 ? 160.844 181.684 156.849 1.00 61.63  ? 465 LEU B CB  1 
ATOM   7429  C  CG  . LEU B 1 465 ? 162.155 181.431 156.097 1.00 61.63  ? 465 LEU B CG  1 
ATOM   7430  C  CD1 . LEU B 1 465 ? 163.202 180.857 157.039 1.00 61.63  ? 465 LEU B CD1 1 
ATOM   7431  C  CD2 . LEU B 1 465 ? 161.975 180.535 154.874 1.00 61.63  ? 465 LEU B CD2 1 
ATOM   7432  N  N   . LEU B 1 466 ? 158.141 181.501 158.458 1.00 60.96  ? 466 LEU B N   1 
ATOM   7433  C  CA  . LEU B 1 466 ? 157.256 181.902 159.538 1.00 60.96  ? 466 LEU B CA  1 
ATOM   7434  C  C   . LEU B 1 466 ? 156.340 180.777 160.000 1.00 60.96  ? 466 LEU B C   1 
ATOM   7435  O  O   . LEU B 1 466 ? 155.686 180.925 161.037 1.00 60.96  ? 466 LEU B O   1 
ATOM   7436  C  CB  . LEU B 1 466 ? 156.406 183.105 159.107 1.00 60.96  ? 466 LEU B CB  1 
ATOM   7437  C  CG  . LEU B 1 466 ? 157.127 184.421 158.804 1.00 60.96  ? 466 LEU B CG  1 
ATOM   7438  C  CD1 . LEU B 1 466 ? 156.146 185.448 158.273 1.00 60.96  ? 466 LEU B CD1 1 
ATOM   7439  C  CD2 . LEU B 1 466 ? 157.837 184.955 160.032 1.00 60.96  ? 466 LEU B CD2 1 
ATOM   7440  N  N   . ASP B 1 467 ? 156.285 179.665 159.264 1.00 63.87  ? 467 ASP B N   1 
ATOM   7441  C  CA  . ASP B 1 467 ? 155.418 178.530 159.580 1.00 63.87  ? 467 ASP B CA  1 
ATOM   7442  C  C   . ASP B 1 467 ? 153.956 178.969 159.676 1.00 63.87  ? 467 ASP B C   1 
ATOM   7443  O  O   . ASP B 1 467 ? 153.303 178.833 160.710 1.00 63.87  ? 467 ASP B O   1 
ATOM   7444  C  CB  . ASP B 1 467 ? 155.873 177.831 160.866 1.00 63.87  ? 467 ASP B CB  1 
ATOM   7445  C  CG  . ASP B 1 467 ? 157.169 177.067 160.687 1.00 63.87  ? 467 ASP B CG  1 
ATOM   7446  O  OD1 . ASP B 1 467 ? 157.435 176.600 159.560 1.00 63.87  ? 467 ASP B OD1 1 
ATOM   7447  O  OD2 . ASP B 1 467 ? 157.920 176.930 161.675 1.00 63.87  ? 467 ASP B OD2 1 
ATOM   7448  N  N   . SER B 1 468 ? 153.446 179.506 158.569 1.00 61.64  ? 468 SER B N   1 
ATOM   7449  C  CA  . SER B 1 468 ? 152.082 180.013 158.557 1.00 61.64  ? 468 SER B CA  1 
ATOM   7450  C  C   . SER B 1 468 ? 151.496 179.910 157.154 1.00 61.64  ? 468 SER B C   1 
ATOM   7451  O  O   . SER B 1 468 ? 152.219 179.779 156.160 1.00 61.64  ? 468 SER B O   1 
ATOM   7452  C  CB  . SER B 1 468 ? 152.021 181.459 159.059 1.00 61.64  ? 468 SER B CB  1 
ATOM   7453  O  OG  . SER B 1 468 ? 152.412 181.545 160.417 1.00 61.64  ? 468 SER B OG  1 
ATOM   7454  N  N   . PHE B 1 469 ? 150.161 179.986 157.097 1.00 62.42  ? 469 PHE B N   1 
ATOM   7455  C  CA  . PHE B 1 469 ? 149.374 179.782 155.888 1.00 62.42  ? 469 PHE B CA  1 
ATOM   7456  C  C   . PHE B 1 469 ? 148.559 181.039 155.626 1.00 62.42  ? 469 PHE B C   1 
ATOM   7457  O  O   . PHE B 1 469 ? 148.261 181.791 156.557 1.00 62.42  ? 469 PHE B O   1 
ATOM   7458  C  CB  . PHE B 1 469 ? 148.380 178.620 156.041 1.00 62.42  ? 469 PHE B CB  1 
ATOM   7459  C  CG  . PHE B 1 469 ? 149.001 177.314 156.434 1.00 62.42  ? 469 PHE B CG  1 
ATOM   7460  C  CD1 . PHE B 1 469 ? 150.337 177.050 156.212 1.00 62.42  ? 469 PHE B CD1 1 
ATOM   7461  C  CD2 . PHE B 1 469 ? 148.240 176.361 157.082 1.00 62.42  ? 469 PHE B CD2 1 
ATOM   7462  C  CE1 . PHE B 1 469 ? 150.884 175.846 156.605 1.00 62.42  ? 469 PHE B CE1 1 
ATOM   7463  C  CE2 . PHE B 1 469 ? 148.797 175.169 157.474 1.00 62.42  ? 469 PHE B CE2 1 
ATOM   7464  C  CZ  . PHE B 1 469 ? 150.120 174.903 157.237 1.00 62.42  ? 469 PHE B CZ  1 
ATOM   7465  N  N   . THR B 1 470 ? 148.173 181.258 154.366 1.00 64.64  ? 470 THR B N   1 
ATOM   7466  C  CA  . THR B 1 470 ? 147.073 182.174 154.057 1.00 64.64  ? 470 THR B CA  1 
ATOM   7467  C  C   . THR B 1 470 ? 146.246 181.622 152.906 1.00 64.64  ? 470 THR B C   1 
ATOM   7468  O  O   . THR B 1 470 ? 146.800 181.221 151.879 1.00 64.64  ? 470 THR B O   1 
ATOM   7469  C  CB  . THR B 1 470 ? 147.552 183.592 153.697 1.00 64.64  ? 470 THR B CB  1 
ATOM   7470  O  OG1 . THR B 1 470 ? 148.480 183.532 152.613 1.00 64.64  ? 470 THR B OG1 1 
ATOM   7471  C  CG2 . THR B 1 470 ? 148.178 184.312 154.881 1.00 64.64  ? 470 THR B CG2 1 
ATOM   7472  N  N   . ARG B 1 471 ? 144.923 181.619 153.067 1.00 74.00  ? 471 ARG B N   1 
ATOM   7473  C  CA  . ARG B 1 471 ? 144.036 181.209 151.987 1.00 74.00  ? 471 ARG B CA  1 
ATOM   7474  C  C   . ARG B 1 471 ? 143.880 182.334 150.972 1.00 74.00  ? 471 ARG B C   1 
ATOM   7475  O  O   . ARG B 1 471 ? 144.499 183.393 151.092 1.00 74.00  ? 471 ARG B O   1 
ATOM   7476  C  CB  . ARG B 1 471 ? 142.668 180.804 152.530 1.00 74.00  ? 471 ARG B CB  1 
ATOM   7477  C  CG  . ARG B 1 471 ? 142.676 179.528 153.344 1.00 74.00  ? 471 ARG B CG  1 
ATOM   7478  C  CD  . ARG B 1 471 ? 141.276 179.169 153.804 1.00 74.00  ? 471 ARG B CD  1 
ATOM   7479  N  NE  . ARG B 1 471 ? 141.269 177.990 154.663 1.00 74.00  ? 471 ARG B NE  1 
ATOM   7480  C  CZ  . ARG B 1 471 ? 141.184 176.744 154.212 1.00 74.00  ? 471 ARG B CZ  1 
ATOM   7481  N  NH1 . ARG B 1 471 ? 141.104 176.513 152.909 1.00 74.00  ? 471 ARG B NH1 1 
ATOM   7482  N  NH2 . ARG B 1 471 ? 141.181 175.728 155.064 1.00 74.00  ? 471 ARG B NH2 1 
ATOM   7483  N  N   . LEU B 1 472 ? 143.037 182.097 149.958 1.00 79.26  ? 472 LEU B N   1 
ATOM   7484  C  CA  . LEU B 1 472 ? 142.874 183.076 148.889 1.00 79.26  ? 472 LEU B CA  1 
ATOM   7485  C  C   . LEU B 1 472 ? 141.556 182.892 148.140 1.00 79.26  ? 472 LEU B C   1 
ATOM   7486  O  O   . LEU B 1 472 ? 140.978 183.870 147.651 1.00 79.26  ? 472 LEU B O   1 
ATOM   7487  C  CB  . LEU B 1 472 ? 144.052 183.010 147.912 1.00 79.26  ? 472 LEU B CB  1 
ATOM   7488  C  CG  . LEU B 1 472 ? 144.251 184.146 146.904 1.00 79.26  ? 472 LEU B CG  1 
ATOM   7489  C  CD1 . LEU B 1 472 ? 145.729 184.296 146.594 1.00 79.26  ? 472 LEU B CD1 1 
ATOM   7490  C  CD2 . LEU B 1 472 ? 143.470 183.920 145.620 1.00 79.26  ? 472 LEU B CD2 1 
ATOM   7491  N  N   . CYS B 1 473 ? 141.082 181.647 148.029 1.00 89.32  ? 473 CYS B N   1 
ATOM   7492  C  CA  . CYS B 1 473 ? 139.840 181.292 147.341 1.00 89.32  ? 473 CYS B CA  1 
ATOM   7493  C  C   . CYS B 1 473 ? 139.927 181.521 145.834 1.00 89.32  ? 473 CYS B C   1 
ATOM   7494  O  O   . CYS B 1 473 ? 140.620 182.430 145.368 1.00 89.32  ? 473 CYS B O   1 
ATOM   7495  C  CB  . CYS B 1 473 ? 138.650 182.058 147.927 1.00 89.32  ? 473 CYS B CB  1 
ATOM   7496  S  SG  . CYS B 1 473 ? 138.250 181.616 149.634 1.00 89.32  ? 473 CYS B SG  1 
ATOM   7497  N  N   . LEU B 1 474 ? 139.218 180.697 145.066 1.00 91.49  ? 474 LEU B N   1 
ATOM   7498  C  CA  . LEU B 1 474 ? 139.298 180.694 143.610 1.00 91.49  ? 474 LEU B CA  1 
ATOM   7499  C  C   . LEU B 1 474 ? 137.895 180.692 143.010 1.00 91.49  ? 474 LEU B C   1 
ATOM   7500  O  O   . LEU B 1 474 ? 136.913 180.607 143.758 1.00 91.49  ? 474 LEU B O   1 
ATOM   7501  C  CB  . LEU B 1 474 ? 140.105 179.480 143.142 1.00 91.49  ? 474 LEU B CB  1 
ATOM   7502  C  CG  . LEU B 1 474 ? 141.590 179.517 143.496 1.00 91.49  ? 474 LEU B CG  1 
ATOM   7503  C  CD1 . LEU B 1 474 ? 142.268 178.222 143.093 1.00 91.49  ? 474 LEU B CD1 1 
ATOM   7504  C  CD2 . LEU B 1 474 ? 142.245 180.707 142.824 1.00 91.49  ? 474 LEU B CD2 1 
ATOM   7505  N  N   . PRO B 1 475 ? 137.746 180.812 141.672 1.00 100.14 ? 475 PRO B N   1 
ATOM   7506  C  CA  . PRO B 1 475 ? 136.412 180.656 141.072 1.00 100.14 ? 475 PRO B CA  1 
ATOM   7507  C  C   . PRO B 1 475 ? 135.748 179.340 141.446 1.00 100.14 ? 475 PRO B C   1 
ATOM   7508  O  O   . PRO B 1 475 ? 136.424 178.329 141.660 1.00 100.14 ? 475 PRO B O   1 
ATOM   7509  C  CB  . PRO B 1 475 ? 136.695 180.741 139.567 1.00 100.14 ? 475 PRO B CB  1 
ATOM   7510  C  CG  . PRO B 1 475 ? 137.904 181.590 139.477 1.00 100.14 ? 475 PRO B CG  1 
ATOM   7511  C  CD  . PRO B 1 475 ? 138.742 181.235 140.669 1.00 100.14 ? 475 PRO B CD  1 
ATOM   7512  N  N   . GLU B 1 476 ? 134.418 179.347 141.527 1.00 106.77 ? 476 GLU B N   1 
ATOM   7513  C  CA  . GLU B 1 476 ? 133.669 178.205 142.036 1.00 106.77 ? 476 GLU B CA  1 
ATOM   7514  C  C   . GLU B 1 476 ? 133.580 177.075 141.018 1.00 106.77 ? 476 GLU B C   1 
ATOM   7515  O  O   . GLU B 1 476 ? 133.131 175.972 141.347 1.00 106.77 ? 476 GLU B O   1 
ATOM   7516  C  CB  . GLU B 1 476 ? 132.265 178.645 142.458 1.00 106.77 ? 476 GLU B CB  1 
ATOM   7517  C  CG  . GLU B 1 476 ? 131.362 179.046 141.302 1.00 106.77 ? 476 GLU B CG  1 
ATOM   7518  C  CD  . GLU B 1 476 ? 131.544 180.495 140.885 1.00 106.77 ? 476 GLU B CD  1 
ATOM   7519  O  OE1 . GLU B 1 476 ? 132.563 181.107 141.269 1.00 106.77 ? 476 GLU B OE1 1 
ATOM   7520  O  OE2 . GLU B 1 476 ? 130.664 181.023 140.173 1.00 106.77 ? 476 GLU B OE2 1 
ATOM   7521  N  N   . ALA B 1 477 ? 134.002 177.333 139.785 1.00 107.43 ? 477 ALA B N   1 
ATOM   7522  C  CA  . ALA B 1 477 ? 133.951 176.317 138.739 1.00 107.43 ? 477 ALA B CA  1 
ATOM   7523  C  C   . ALA B 1 477 ? 135.281 176.219 138.000 1.00 107.43 ? 477 ALA B C   1 
ATOM   7524  O  O   . ALA B 1 477 ? 135.737 177.186 137.391 1.00 107.43 ? 477 ALA B O   1 
ATOM   7525  C  CB  . ALA B 1 477 ? 132.822 176.617 137.765 1.00 107.43 ? 477 ALA B CB  1 
ATOM   7526  N  N   . SER B 1 483 ? 136.572 168.309 139.249 1.00 94.70  ? 483 SER B N   1 
ATOM   7527  C  CA  . SER B 1 483 ? 137.179 169.619 139.051 1.00 94.70  ? 483 SER B CA  1 
ATOM   7528  C  C   . SER B 1 483 ? 138.499 169.731 139.804 1.00 94.70  ? 483 SER B C   1 
ATOM   7529  O  O   . SER B 1 483 ? 138.520 169.770 141.034 1.00 94.70  ? 483 SER B O   1 
ATOM   7530  C  CB  . SER B 1 483 ? 136.223 170.727 139.500 1.00 94.70  ? 483 SER B CB  1 
ATOM   7531  O  OG  . SER B 1 483 ? 136.014 170.683 140.900 1.00 94.70  ? 483 SER B OG  1 
ATOM   7532  N  N   . LEU B 1 484 ? 139.600 169.780 139.061 1.00 89.07  ? 484 LEU B N   1 
ATOM   7533  C  CA  . LEU B 1 484 ? 140.909 169.912 139.680 1.00 89.07  ? 484 LEU B CA  1 
ATOM   7534  C  C   . LEU B 1 484 ? 141.613 171.168 139.181 1.00 89.07  ? 484 LEU B C   1 
ATOM   7535  O  O   . LEU B 1 484 ? 141.100 171.901 138.332 1.00 89.07  ? 484 LEU B O   1 
ATOM   7536  C  CB  . LEU B 1 484 ? 141.763 168.680 139.390 1.00 89.07  ? 484 LEU B CB  1 
ATOM   7537  C  CG  . LEU B 1 484 ? 141.265 167.374 140.007 1.00 89.07  ? 484 LEU B CG  1 
ATOM   7538  C  CD1 . LEU B 1 484 ? 142.123 166.208 139.550 1.00 89.07  ? 484 LEU B CD1 1 
ATOM   7539  C  CD2 . LEU B 1 484 ? 141.248 167.473 141.523 1.00 89.07  ? 484 LEU B CD2 1 
ATOM   7540  N  N   . TRP B 1 485 ? 142.805 171.414 139.721 1.00 83.30  ? 485 TRP B N   1 
ATOM   7541  C  CA  . TRP B 1 485 ? 143.586 172.592 139.379 1.00 83.30  ? 485 TRP B CA  1 
ATOM   7542  C  C   . TRP B 1 485 ? 145.069 172.269 139.484 1.00 83.30  ? 485 TRP B C   1 
ATOM   7543  O  O   . TRP B 1 485 ? 145.473 171.338 140.185 1.00 83.30  ? 485 TRP B O   1 
ATOM   7544  C  CB  . TRP B 1 485 ? 143.244 173.775 140.293 1.00 83.30  ? 485 TRP B CB  1 
ATOM   7545  C  CG  . TRP B 1 485 ? 141.827 174.264 140.175 1.00 83.30  ? 485 TRP B CG  1 
ATOM   7546  C  CD1 . TRP B 1 485 ? 140.770 173.883 140.944 1.00 83.30  ? 485 TRP B CD1 1 
ATOM   7547  C  CD2 . TRP B 1 485 ? 141.322 175.242 139.258 1.00 83.30  ? 485 TRP B CD2 1 
ATOM   7548  N  NE1 . TRP B 1 485 ? 139.634 174.549 140.555 1.00 83.30  ? 485 TRP B NE1 1 
ATOM   7549  C  CE2 . TRP B 1 485 ? 139.947 175.391 139.522 1.00 83.30  ? 485 TRP B CE2 1 
ATOM   7550  C  CE3 . TRP B 1 485 ? 141.896 175.998 138.234 1.00 83.30  ? 485 TRP B CE3 1 
ATOM   7551  C  CZ2 . TRP B 1 485 ? 139.139 176.266 138.801 1.00 83.30  ? 485 TRP B CZ2 1 
ATOM   7552  C  CZ3 . TRP B 1 485 ? 141.093 176.870 137.523 1.00 83.30  ? 485 TRP B CZ3 1 
ATOM   7553  C  CH2 . TRP B 1 485 ? 139.730 176.995 137.807 1.00 83.30  ? 485 TRP B CH2 1 
ATOM   7554  N  N   . LYS B 1 486 ? 145.875 173.058 138.778 1.00 73.41  ? 486 LYS B N   1 
ATOM   7555  C  CA  . LYS B 1 486 ? 147.317 172.893 138.700 1.00 73.41  ? 486 LYS B CA  1 
ATOM   7556  C  C   . LYS B 1 486 ? 147.965 174.268 138.688 1.00 73.41  ? 486 LYS B C   1 
ATOM   7557  O  O   . LYS B 1 486 ? 147.473 175.195 138.038 1.00 73.41  ? 486 LYS B O   1 
ATOM   7558  C  CB  . LYS B 1 486 ? 147.736 172.120 137.439 1.00 73.41  ? 486 LYS B CB  1 
ATOM   7559  C  CG  . LYS B 1 486 ? 147.151 170.722 137.313 1.00 73.41  ? 486 LYS B CG  1 
ATOM   7560  C  CD  . LYS B 1 486 ? 147.747 169.766 138.328 1.00 73.41  ? 486 LYS B CD  1 
ATOM   7561  C  CE  . LYS B 1 486 ? 147.125 168.388 138.208 1.00 73.41  ? 486 LYS B CE  1 
ATOM   7562  N  NZ  . LYS B 1 486 ? 147.481 167.730 136.928 1.00 73.41  ? 486 LYS B NZ  1 
ATOM   7563  N  N   . ILE B 1 487 ? 149.080 174.395 139.402 1.00 64.91  ? 487 ILE B N   1 
ATOM   7564  C  CA  . ILE B 1 487 ? 149.756 175.672 139.589 1.00 64.91  ? 487 ILE B CA  1 
ATOM   7565  C  C   . ILE B 1 487 ? 151.063 175.657 138.813 1.00 64.91  ? 487 ILE B C   1 
ATOM   7566  O  O   . ILE B 1 487 ? 151.755 174.634 138.769 1.00 64.91  ? 487 ILE B O   1 
ATOM   7567  C  CB  . ILE B 1 487 ? 150.012 175.963 141.078 1.00 64.91  ? 487 ILE B CB  1 
ATOM   7568  C  CG1 . ILE B 1 487 ? 148.696 175.963 141.834 1.00 64.91  ? 487 ILE B CG1 1 
ATOM   7569  C  CG2 . ILE B 1 487 ? 150.655 177.319 141.257 1.00 64.91  ? 487 ILE B CG2 1 
ATOM   7570  C  CD1 . ILE B 1 487 ? 147.752 177.022 141.346 1.00 64.91  ? 487 ILE B CD1 1 
ATOM   7571  N  N   . ALA B 1 488 ? 151.398 176.792 138.204 1.00 65.51  ? 488 ALA B N   1 
ATOM   7572  C  CA  . ALA B 1 488 ? 152.689 176.964 137.548 1.00 65.51  ? 488 ALA B CA  1 
ATOM   7573  C  C   . ALA B 1 488 ? 153.063 178.433 137.622 1.00 65.51  ? 488 ALA B C   1 
ATOM   7574  O  O   . ALA B 1 488 ? 152.483 179.256 136.908 1.00 65.51  ? 488 ALA B O   1 
ATOM   7575  C  CB  . ALA B 1 488 ? 152.643 176.490 136.097 1.00 65.51  ? 488 ALA B CB  1 
ATOM   7576  N  N   . SER B 1 489 ? 154.018 178.761 138.487 1.00 67.55  ? 489 SER B N   1 
ATOM   7577  C  CA  . SER B 1 489 ? 154.475 180.134 138.649 1.00 67.55  ? 489 SER B CA  1 
ATOM   7578  C  C   . SER B 1 489 ? 155.468 180.474 137.548 1.00 67.55  ? 489 SER B C   1 
ATOM   7579  O  O   . SER B 1 489 ? 156.676 180.278 137.710 1.00 67.55  ? 489 SER B O   1 
ATOM   7580  C  CB  . SER B 1 489 ? 155.125 180.333 140.015 1.00 67.55  ? 489 SER B CB  1 
ATOM   7581  O  OG  . SER B 1 489 ? 156.335 179.604 140.101 1.00 67.55  ? 489 SER B OG  1 
ATOM   7582  N  N   . CYS B 1 490 ? 154.955 180.988 136.434 1.00 79.73  ? 490 CYS B N   1 
ATOM   7583  C  CA  . CYS B 1 490 ? 155.771 181.291 135.268 1.00 79.73  ? 490 CYS B CA  1 
ATOM   7584  C  C   . CYS B 1 490 ? 156.405 182.662 135.430 1.00 79.73  ? 490 CYS B C   1 
ATOM   7585  O  O   . CYS B 1 490 ? 155.694 183.668 135.536 1.00 79.73  ? 490 CYS B O   1 
ATOM   7586  C  CB  . CYS B 1 490 ? 154.936 181.248 133.986 1.00 79.73  ? 490 CYS B CB  1 
ATOM   7587  S  SG  . CYS B 1 490 ? 155.876 181.525 132.479 1.00 79.73  ? 490 CYS B SG  1 
ATOM   7588  N  N   . ASN B 1 491 ? 157.740 182.688 135.457 1.00 84.28  ? 491 ASN B N   1 
ATOM   7589  C  CA  . ASN B 1 491 ? 158.520 183.926 135.490 1.00 84.28  ? 491 ASN B CA  1 
ATOM   7590  C  C   . ASN B 1 491 ? 158.040 184.863 136.595 1.00 84.28  ? 491 ASN B C   1 
ATOM   7591  O  O   . ASN B 1 491 ? 158.562 184.869 137.712 1.00 84.28  ? 491 ASN B O   1 
ATOM   7592  C  CB  . ASN B 1 491 ? 158.487 184.627 134.129 1.00 84.28  ? 491 ASN B CB  1 
ATOM   7593  C  CG  . ASN B 1 491 ? 159.493 185.760 134.027 1.00 84.28  ? 491 ASN B CG  1 
ATOM   7594  O  OD1 . ASN B 1 491 ? 160.225 186.048 134.974 1.00 84.28  ? 491 ASN B OD1 1 
ATOM   7595  N  ND2 . ASN B 1 491 ? 159.535 186.410 132.869 1.00 84.28  ? 491 ASN B ND2 1 
ATOM   7596  N  N   . GLY B 1 492 ? 157.027 185.665 136.278 1.00 79.68  ? 492 GLY B N   1 
ATOM   7597  C  CA  . GLY B 1 492 ? 156.570 186.671 137.211 1.00 79.68  ? 492 GLY B CA  1 
ATOM   7598  C  C   . GLY B 1 492 ? 155.241 186.394 137.871 1.00 79.68  ? 492 GLY B C   1 
ATOM   7599  O  O   . GLY B 1 492 ? 155.017 186.856 138.991 1.00 79.68  ? 492 GLY B O   1 
ATOM   7600  N  N   . SER B 1 493 ? 154.347 185.654 137.219 1.00 72.52  ? 493 SER B N   1 
ATOM   7601  C  CA  . SER B 1 493 ? 153.002 185.466 137.742 1.00 72.52  ? 493 SER B CA  1 
ATOM   7602  C  C   . SER B 1 493 ? 152.726 183.995 138.008 1.00 72.52  ? 493 SER B C   1 
ATOM   7603  O  O   . SER B 1 493 ? 153.582 183.134 137.795 1.00 72.52  ? 493 SER B O   1 
ATOM   7604  C  CB  . SER B 1 493 ? 151.943 186.013 136.789 1.00 72.52  ? 493 SER B CB  1 
ATOM   7605  O  OG  . SER B 1 493 ? 150.647 185.800 137.320 1.00 72.52  ? 493 SER B OG  1 
ATOM   7606  N  N   . ILE B 1 494 ? 151.510 183.721 138.469 1.00 67.73  ? 494 ILE B N   1 
ATOM   7607  C  CA  . ILE B 1 494 ? 151.094 182.386 138.880 1.00 67.73  ? 494 ILE B CA  1 
ATOM   7608  C  C   . ILE B 1 494 ? 149.931 181.957 137.999 1.00 67.73  ? 494 ILE B C   1 
ATOM   7609  O  O   . ILE B 1 494 ? 148.804 182.435 138.173 1.00 67.73  ? 494 ILE B O   1 
ATOM   7610  C  CB  . ILE B 1 494 ? 150.690 182.362 140.360 1.00 67.73  ? 494 ILE B CB  1 
ATOM   7611  C  CG1 . ILE B 1 494 ? 151.853 182.811 141.235 1.00 67.73  ? 494 ILE B CG1 1 
ATOM   7612  C  CG2 . ILE B 1 494 ? 150.245 180.973 140.770 1.00 67.73  ? 494 ILE B CG2 1 
ATOM   7613  C  CD1 . ILE B 1 494 ? 151.440 183.121 142.646 1.00 67.73  ? 494 ILE B CD1 1 
ATOM   7614  N  N   . TYR B 1 495 ? 150.192 181.054 137.061 1.00 71.08  ? 495 TYR B N   1 
ATOM   7615  C  CA  . TYR B 1 495 ? 149.161 180.546 136.170 1.00 71.08  ? 495 TYR B CA  1 
ATOM   7616  C  C   . TYR B 1 495 ? 148.504 179.319 136.783 1.00 71.08  ? 495 TYR B C   1 
ATOM   7617  O  O   . TYR B 1 495 ? 149.176 178.481 137.391 1.00 71.08  ? 495 TYR B O   1 
ATOM   7618  C  CB  . TYR B 1 495 ? 149.742 180.209 134.800 1.00 71.08  ? 495 TYR B CB  1 
ATOM   7619  C  CG  . TYR B 1 495 ? 150.183 181.427 134.033 1.00 71.08  ? 495 TYR B CG  1 
ATOM   7620  C  CD1 . TYR B 1 495 ? 149.275 182.179 133.309 1.00 71.08  ? 495 TYR B CD1 1 
ATOM   7621  C  CD2 . TYR B 1 495 ? 151.502 181.840 134.053 1.00 71.08  ? 495 TYR B CD2 1 
ATOM   7622  C  CE1 . TYR B 1 495 ? 149.673 183.299 132.610 1.00 71.08  ? 495 TYR B CE1 1 
ATOM   7623  C  CE2 . TYR B 1 495 ? 151.910 182.961 133.359 1.00 71.08  ? 495 TYR B CE2 1 
ATOM   7624  C  CZ  . TYR B 1 495 ? 150.992 183.687 132.639 1.00 71.08  ? 495 TYR B CZ  1 
ATOM   7625  O  OH  . TYR B 1 495 ? 151.391 184.805 131.945 1.00 71.08  ? 495 TYR B OH  1 
ATOM   7626  N  N   . VAL B 1 496 ? 147.188 179.220 136.619 1.00 74.50  ? 496 VAL B N   1 
ATOM   7627  C  CA  . VAL B 1 496 ? 146.384 178.181 137.249 1.00 74.50  ? 496 VAL B CA  1 
ATOM   7628  C  C   . VAL B 1 496 ? 145.576 177.486 136.160 1.00 74.50  ? 496 VAL B C   1 
ATOM   7629  O  O   . VAL B 1 496 ? 144.569 178.027 135.688 1.00 74.50  ? 496 VAL B O   1 
ATOM   7630  C  CB  . VAL B 1 496 ? 145.461 178.762 138.332 1.00 74.50  ? 496 VAL B CB  1 
ATOM   7631  C  CG1 . VAL B 1 496 ? 144.684 177.664 139.008 1.00 74.50  ? 496 VAL B CG1 1 
ATOM   7632  C  CG2 . VAL B 1 496 ? 146.259 179.548 139.349 1.00 74.50  ? 496 VAL B CG2 1 
ATOM   7633  N  N   . PHE B 1 497 ? 146.015 176.293 135.764 1.00 79.57  ? 497 PHE B N   1 
ATOM   7634  C  CA  . PHE B 1 497 ? 145.373 175.513 134.714 1.00 79.57  ? 497 PHE B CA  1 
ATOM   7635  C  C   . PHE B 1 497 ? 144.410 174.514 135.338 1.00 79.57  ? 497 PHE B C   1 
ATOM   7636  O  O   . PHE B 1 497 ? 144.767 173.822 136.291 1.00 79.57  ? 497 PHE B O   1 
ATOM   7637  C  CB  . PHE B 1 497 ? 146.410 174.751 133.883 1.00 79.57  ? 497 PHE B CB  1 
ATOM   7638  C  CG  . PHE B 1 497 ? 147.392 175.630 133.168 1.00 79.57  ? 497 PHE B CG  1 
ATOM   7639  C  CD1 . PHE B 1 497 ? 147.062 176.234 131.970 1.00 79.57  ? 497 PHE B CD1 1 
ATOM   7640  C  CD2 . PHE B 1 497 ? 148.652 175.841 133.690 1.00 79.57  ? 497 PHE B CD2 1 
ATOM   7641  C  CE1 . PHE B 1 497 ? 147.968 177.035 131.313 1.00 79.57  ? 497 PHE B CE1 1 
ATOM   7642  C  CE2 . PHE B 1 497 ? 149.560 176.640 133.036 1.00 79.57  ? 497 PHE B CE2 1 
ATOM   7643  C  CZ  . PHE B 1 497 ? 149.217 177.239 131.847 1.00 79.57  ? 497 PHE B CZ  1 
ATOM   7644  N  N   . ARG B 1 498 ? 143.199 174.416 134.800 1.00 99.70  ? 498 ARG B N   1 
ATOM   7645  C  CA  . ARG B 1 498 ? 142.223 173.447 135.293 1.00 99.70  ? 498 ARG B CA  1 
ATOM   7646  C  C   . ARG B 1 498 ? 142.178 172.282 134.312 1.00 99.70  ? 498 ARG B C   1 
ATOM   7647  O  O   . ARG B 1 498 ? 142.155 172.488 133.094 1.00 99.70  ? 498 ARG B O   1 
ATOM   7648  C  CB  . ARG B 1 498 ? 140.852 174.092 135.494 1.00 99.70  ? 498 ARG B CB  1 
ATOM   7649  C  CG  . ARG B 1 498 ? 140.201 174.662 134.257 1.00 99.70  ? 498 ARG B CG  1 
ATOM   7650  C  CD  . ARG B 1 498 ? 139.107 173.748 133.738 1.00 99.70  ? 498 ARG B CD  1 
ATOM   7651  N  NE  . ARG B 1 498 ? 138.013 173.650 134.701 1.00 99.70  ? 498 ARG B NE  1 
ATOM   7652  C  CZ  . ARG B 1 498 ? 137.301 172.550 134.923 1.00 99.70  ? 498 ARG B CZ  1 
ATOM   7653  N  NH1 . ARG B 1 498 ? 137.559 171.441 134.247 1.00 99.70  ? 498 ARG B NH1 1 
ATOM   7654  N  NH2 . ARG B 1 498 ? 136.327 172.561 135.822 1.00 99.70  ? 498 ARG B NH2 1 
ATOM   7655  N  N   . ASP B 1 499 ? 142.177 171.059 134.846 1.00 96.71  ? 499 ASP B N   1 
ATOM   7656  C  CA  . ASP B 1 499 ? 142.398 169.857 134.049 1.00 96.71  ? 499 ASP B CA  1 
ATOM   7657  C  C   . ASP B 1 499 ? 141.349 169.660 132.963 1.00 96.71  ? 499 ASP B C   1 
ATOM   7658  O  O   . ASP B 1 499 ? 141.623 169.900 131.783 1.00 96.71  ? 499 ASP B O   1 
ATOM   7659  C  CB  . ASP B 1 499 ? 142.438 168.621 134.950 1.00 96.71  ? 499 ASP B CB  1 
ATOM   7660  C  CG  . ASP B 1 499 ? 143.684 168.567 135.808 1.00 96.71  ? 499 ASP B CG  1 
ATOM   7661  O  OD1 . ASP B 1 499 ? 144.720 169.123 135.389 1.00 96.71  ? 499 ASP B OD1 1 
ATOM   7662  O  OD2 . ASP B 1 499 ? 143.632 167.958 136.895 1.00 96.71  ? 499 ASP B OD2 1 
ATOM   7663  N  N   . ARG B 1 500 ? 140.158 169.204 133.349 1.00 109.81 ? 500 ARG B N   1 
ATOM   7664  C  CA  . ARG B 1 500 ? 139.109 168.870 132.393 1.00 109.81 ? 500 ARG B CA  1 
ATOM   7665  C  C   . ARG B 1 500 ? 138.771 170.059 131.501 1.00 109.81 ? 500 ARG B C   1 
ATOM   7666  O  O   . ARG B 1 500 ? 137.924 170.889 131.850 1.00 109.81 ? 500 ARG B O   1 
ATOM   7667  C  CB  . ARG B 1 500 ? 137.861 168.377 133.133 1.00 109.81 ? 500 ARG B CB  1 
ATOM   7668  C  CG  . ARG B 1 500 ? 136.680 168.013 132.240 1.00 109.81 ? 500 ARG B CG  1 
ATOM   7669  C  CD  . ARG B 1 500 ? 136.978 166.805 131.366 1.00 109.81 ? 500 ARG B CD  1 
ATOM   7670  N  NE  . ARG B 1 500 ? 135.816 166.405 130.575 1.00 109.81 ? 500 ARG B NE  1 
ATOM   7671  C  CZ  . ARG B 1 500 ? 135.499 166.920 129.391 1.00 109.81 ? 500 ARG B CZ  1 
ATOM   7672  N  NH1 . ARG B 1 500 ? 136.258 167.862 128.849 1.00 109.81 ? 500 ARG B NH1 1 
ATOM   7673  N  NH2 . ARG B 1 500 ? 134.421 166.492 128.748 1.00 109.81 ? 500 ARG B NH2 1 
ATOM   7674  N  N   . TYR B 1 501 ? 139.441 170.155 130.352 1.00 111.88 ? 501 TYR B N   1 
ATOM   7675  C  CA  . TYR B 1 501 ? 139.134 171.193 129.377 1.00 111.88 ? 501 TYR B CA  1 
ATOM   7676  C  C   . TYR B 1 501 ? 137.731 170.998 128.819 1.00 111.88 ? 501 TYR B C   1 
ATOM   7677  O  O   . TYR B 1 501 ? 137.564 170.457 127.721 1.00 111.88 ? 501 TYR B O   1 
ATOM   7678  C  CB  . TYR B 1 501 ? 140.154 171.196 128.236 1.00 111.88 ? 501 TYR B CB  1 
ATOM   7679  C  CG  . TYR B 1 501 ? 141.523 171.721 128.605 1.00 111.88 ? 501 TYR B CG  1 
ATOM   7680  C  CD1 . TYR B 1 501 ? 141.742 172.366 129.812 1.00 111.88 ? 501 TYR B CD1 1 
ATOM   7681  C  CD2 . TYR B 1 501 ? 142.591 171.602 127.726 1.00 111.88 ? 501 TYR B CD2 1 
ATOM   7682  C  CE1 . TYR B 1 501 ? 142.989 172.858 130.145 1.00 111.88 ? 501 TYR B CE1 1 
ATOM   7683  C  CE2 . TYR B 1 501 ? 143.840 172.090 128.050 1.00 111.88 ? 501 TYR B CE2 1 
ATOM   7684  C  CZ  . TYR B 1 501 ? 144.032 172.721 129.258 1.00 111.88 ? 501 TYR B CZ  1 
ATOM   7685  O  OH  . TYR B 1 501 ? 145.276 173.208 129.584 1.00 111.88 ? 501 TYR B OH  1 
ATOM   7686  N  N   . LYS B 1 502 ? 136.719 171.432 129.565 1.00 117.87 ? 502 LYS B N   1 
ATOM   7687  C  CA  . LYS B 1 502 ? 135.331 171.298 129.147 1.00 117.87 ? 502 LYS B CA  1 
ATOM   7688  C  C   . LYS B 1 502 ? 134.900 172.385 128.170 1.00 117.87 ? 502 LYS B C   1 
ATOM   7689  O  O   . LYS B 1 502 ? 133.697 172.623 128.017 1.00 117.87 ? 502 LYS B O   1 
ATOM   7690  C  CB  . LYS B 1 502 ? 134.415 171.289 130.374 1.00 117.87 ? 502 LYS B CB  1 
ATOM   7691  C  CG  . LYS B 1 502 ? 134.416 172.582 131.168 1.00 117.87 ? 502 LYS B CG  1 
ATOM   7692  C  CD  . LYS B 1 502 ? 133.553 172.458 132.413 1.00 117.87 ? 502 LYS B CD  1 
ATOM   7693  C  CE  . LYS B 1 502 ? 132.078 172.373 132.059 1.00 117.87 ? 502 LYS B CE  1 
ATOM   7694  N  NZ  . LYS B 1 502 ? 131.583 173.641 131.457 1.00 117.87 ? 502 LYS B NZ  1 
ATOM   7695  N  N   . LYS B 1 503 ? 135.855 173.049 127.514 1.00 120.22 ? 503 LYS B N   1 
ATOM   7696  C  CA  . LYS B 1 503 ? 135.627 174.038 126.462 1.00 120.22 ? 503 LYS B CA  1 
ATOM   7697  C  C   . LYS B 1 503 ? 134.878 175.272 126.948 1.00 120.22 ? 503 LYS B C   1 
ATOM   7698  O  O   . LYS B 1 503 ? 135.332 176.397 126.709 1.00 120.22 ? 503 LYS B O   1 
ATOM   7699  C  CB  . LYS B 1 503 ? 134.887 173.429 125.266 1.00 120.22 ? 503 LYS B CB  1 
ATOM   7700  C  CG  . LYS B 1 503 ? 134.714 174.380 124.094 1.00 120.22 ? 503 LYS B CG  1 
ATOM   7701  C  CD  . LYS B 1 503 ? 136.050 174.656 123.420 1.00 120.22 ? 503 LYS B CD  1 
ATOM   7702  C  CE  . LYS B 1 503 ? 135.882 175.514 122.177 1.00 120.22 ? 503 LYS B CE  1 
ATOM   7703  N  NZ  . LYS B 1 503 ? 137.191 175.840 121.548 1.00 120.22 ? 503 LYS B NZ  1 
ATOM   7704  N  N   . GLY B 1 504 ? 133.737 175.098 127.613 1.00 120.31 ? 504 GLY B N   1 
ATOM   7705  C  CA  . GLY B 1 504 ? 132.951 176.216 128.101 1.00 120.31 ? 504 GLY B CA  1 
ATOM   7706  C  C   . GLY B 1 504 ? 133.720 177.145 129.017 1.00 120.31 ? 504 GLY B C   1 
ATOM   7707  O  O   . GLY B 1 504 ? 133.724 178.363 128.816 1.00 120.31 ? 504 GLY B O   1 
ATOM   7708  N  N   . ASP B 1 505 ? 134.373 176.582 130.029 1.00 117.86 ? 505 ASP B N   1 
ATOM   7709  C  CA  . ASP B 1 505 ? 135.208 177.380 130.909 1.00 117.86 ? 505 ASP B CA  1 
ATOM   7710  C  C   . ASP B 1 505 ? 136.460 177.846 130.173 1.00 117.86 ? 505 ASP B C   1 
ATOM   7711  O  O   . ASP B 1 505 ? 136.906 177.236 129.197 1.00 117.86 ? 505 ASP B O   1 
ATOM   7712  C  CB  . ASP B 1 505 ? 135.595 176.585 132.156 1.00 117.86 ? 505 ASP B CB  1 
ATOM   7713  C  CG  . ASP B 1 505 ? 134.416 176.328 133.074 1.00 117.86 ? 505 ASP B CG  1 
ATOM   7714  O  OD1 . ASP B 1 505 ? 133.474 177.148 133.076 1.00 117.86 ? 505 ASP B OD1 1 
ATOM   7715  O  OD2 . ASP B 1 505 ? 134.433 175.311 133.798 1.00 117.86 ? 505 ASP B OD2 1 
ATOM   7716  N  N   . ALA B 1 506 ? 137.034 178.947 130.661 1.00 109.05 ? 506 ALA B N   1 
ATOM   7717  C  CA  . ALA B 1 506 ? 138.244 179.494 130.062 1.00 109.05 ? 506 ALA B CA  1 
ATOM   7718  C  C   . ALA B 1 506 ? 139.480 178.661 130.370 1.00 109.05 ? 506 ALA B C   1 
ATOM   7719  O  O   . ALA B 1 506 ? 140.592 179.092 130.046 1.00 109.05 ? 506 ALA B O   1 
ATOM   7720  C  CB  . ALA B 1 506 ? 138.460 180.929 130.536 1.00 109.05 ? 506 ALA B CB  1 
ATOM   7721  N  N   . ASN B 1 507 ? 139.298 177.499 131.004 1.00 107.44 ? 507 ASN B N   1 
ATOM   7722  C  CA  . ASN B 1 507 ? 140.302 176.486 131.328 1.00 107.44 ? 507 ASN B CA  1 
ATOM   7723  C  C   . ASN B 1 507 ? 141.744 176.971 131.464 1.00 107.44 ? 507 ASN B C   1 
ATOM   7724  O  O   . ASN B 1 507 ? 142.680 176.209 131.199 1.00 107.44 ? 507 ASN B O   1 
ATOM   7725  C  CB  . ASN B 1 507 ? 140.234 175.348 130.299 1.00 107.44 ? 507 ASN B CB  1 
ATOM   7726  C  CG  . ASN B 1 507 ? 140.626 175.775 128.889 1.00 107.44 ? 507 ASN B CG  1 
ATOM   7727  O  OD1 . ASN B 1 507 ? 141.113 176.879 128.657 1.00 107.44 ? 507 ASN B OD1 1 
ATOM   7728  N  ND2 . ASN B 1 507 ? 140.410 174.880 127.933 1.00 107.44 ? 507 ASN B ND2 1 
ATOM   7729  N  N   . THR B 1 508 ? 141.933 178.220 131.891 1.00 95.74  ? 508 THR B N   1 
ATOM   7730  C  CA  . THR B 1 508 ? 143.255 178.769 132.174 1.00 95.74  ? 508 THR B CA  1 
ATOM   7731  C  C   . THR B 1 508 ? 143.065 180.133 132.816 1.00 95.74  ? 508 THR B C   1 
ATOM   7732  O  O   . THR B 1 508 ? 142.341 180.973 132.276 1.00 95.74  ? 508 THR B O   1 
ATOM   7733  C  CB  . THR B 1 508 ? 144.113 178.907 130.910 1.00 95.74  ? 508 THR B CB  1 
ATOM   7734  O  OG1 . THR B 1 508 ? 144.312 177.620 130.311 1.00 95.74  ? 508 THR B OG1 1 
ATOM   7735  C  CG2 . THR B 1 508 ? 145.464 179.496 131.259 1.00 95.74  ? 508 THR B CG2 1 
ATOM   7736  N  N   . TYR B 1 509 ? 143.711 180.352 133.954 1.00 85.34  ? 509 TYR B N   1 
ATOM   7737  C  CA  . TYR B 1 509 ? 143.590 181.602 134.686 1.00 85.34  ? 509 TYR B CA  1 
ATOM   7738  C  C   . TYR B 1 509 ? 144.971 182.135 135.047 1.00 85.34  ? 509 TYR B C   1 
ATOM   7739  O  O   . TYR B 1 509 ? 146.002 181.537 134.727 1.00 85.34  ? 509 TYR B O   1 
ATOM   7740  C  CB  . TYR B 1 509 ? 142.724 181.408 135.930 1.00 85.34  ? 509 TYR B CB  1 
ATOM   7741  C  CG  . TYR B 1 509 ? 141.285 181.093 135.603 1.00 85.34  ? 509 TYR B CG  1 
ATOM   7742  C  CD1 . TYR B 1 509 ? 140.397 182.099 135.255 1.00 85.34  ? 509 TYR B CD1 1 
ATOM   7743  C  CD2 . TYR B 1 509 ? 140.817 179.789 135.635 1.00 85.34  ? 509 TYR B CD2 1 
ATOM   7744  C  CE1 . TYR B 1 509 ? 139.082 181.815 134.953 1.00 85.34  ? 509 TYR B CE1 1 
ATOM   7745  C  CE2 . TYR B 1 509 ? 139.503 179.496 135.333 1.00 85.34  ? 509 TYR B CE2 1 
ATOM   7746  C  CZ  . TYR B 1 509 ? 138.640 180.513 134.993 1.00 85.34  ? 509 TYR B CZ  1 
ATOM   7747  O  OH  . TYR B 1 509 ? 137.329 180.226 134.691 1.00 85.34  ? 509 TYR B OH  1 
ATOM   7748  N  N   . LYS B 1 510 ? 144.978 183.277 135.722 1.00 75.00  ? 510 LYS B N   1 
ATOM   7749  C  CA  . LYS B 1 510 ? 146.212 183.970 136.070 1.00 75.00  ? 510 LYS B CA  1 
ATOM   7750  C  C   . LYS B 1 510 ? 145.923 184.968 137.187 1.00 75.00  ? 510 LYS B C   1 
ATOM   7751  O  O   . LYS B 1 510 ? 145.409 186.063 136.959 1.00 75.00  ? 510 LYS B O   1 
ATOM   7752  C  CB  . LYS B 1 510 ? 146.811 184.648 134.837 1.00 75.00  ? 510 LYS B CB  1 
ATOM   7753  C  CG  . LYS B 1 510 ? 148.097 185.415 135.077 1.00 75.00  ? 510 LYS B CG  1 
ATOM   7754  C  CD  . LYS B 1 510 ? 147.837 186.910 135.120 1.00 75.00  ? 510 LYS B CD  1 
ATOM   7755  C  CE  . LYS B 1 510 ? 149.118 187.698 135.315 1.00 75.00  ? 510 LYS B CE  1 
ATOM   7756  N  NZ  . LYS B 1 510 ? 150.051 187.538 134.169 1.00 75.00  ? 510 LYS B NZ  1 
ATOM   7757  N  N   . LEU B 1 511 ? 146.240 184.593 138.423 1.00 71.50  ? 511 LEU B N   1 
ATOM   7758  C  CA  . LEU B 1 511 ? 145.919 185.459 139.546 1.00 71.50  ? 511 LEU B CA  1 
ATOM   7759  C  C   . LEU B 1 511 ? 147.119 186.316 139.927 1.00 71.50  ? 511 LEU B C   1 
ATOM   7760  O  O   . LEU B 1 511 ? 148.276 185.917 139.772 1.00 71.50  ? 511 LEU B O   1 
ATOM   7761  C  CB  . LEU B 1 511 ? 145.463 184.641 140.756 1.00 71.50  ? 511 LEU B CB  1 
ATOM   7762  C  CG  . LEU B 1 511 ? 146.524 183.934 141.601 1.00 71.50  ? 511 LEU B CG  1 
ATOM   7763  C  CD1 . LEU B 1 511 ? 145.957 183.569 142.957 1.00 71.50  ? 511 LEU B CD1 1 
ATOM   7764  C  CD2 . LEU B 1 511 ? 147.041 182.700 140.903 1.00 71.50  ? 511 LEU B CD2 1 
ATOM   7765  N  N   . ASP B 1 512 ? 146.827 187.517 140.420 1.00 69.58  ? 512 ASP B N   1 
ATOM   7766  C  CA  . ASP B 1 512 ? 147.842 188.392 140.975 1.00 69.58  ? 512 ASP B CA  1 
ATOM   7767  C  C   . ASP B 1 512 ? 147.849 188.208 142.481 1.00 69.58  ? 512 ASP B C   1 
ATOM   7768  O  O   . ASP B 1 512 ? 146.880 188.611 143.143 1.00 69.58  ? 512 ASP B O   1 
ATOM   7769  C  CB  . ASP B 1 512 ? 147.553 189.844 140.613 1.00 69.58  ? 512 ASP B CB  1 
ATOM   7770  C  CG  . ASP B 1 512 ? 148.722 190.765 140.899 1.00 69.58  ? 512 ASP B CG  1 
ATOM   7771  O  OD1 . ASP B 1 512 ? 149.761 190.287 141.399 1.00 69.58  ? 512 ASP B OD1 1 
ATOM   7772  O  OD2 . ASP B 1 512 ? 148.602 191.975 140.617 1.00 69.58  ? 512 ASP B OD2 1 
ATOM   7773  N  N   . PRO B 1 513 ? 148.892 187.614 143.065 1.00 62.51  ? 513 PRO B N   1 
ATOM   7774  C  CA  . PRO B 1 513 ? 148.813 187.220 144.480 1.00 62.51  ? 513 PRO B CA  1 
ATOM   7775  C  C   . PRO B 1 513 ? 148.745 188.386 145.448 1.00 62.51  ? 513 PRO B C   1 
ATOM   7776  O  O   . PRO B 1 513 ? 148.538 188.160 146.646 1.00 62.51  ? 513 PRO B O   1 
ATOM   7777  C  CB  . PRO B 1 513 ? 150.091 186.398 144.682 1.00 62.51  ? 513 PRO B CB  1 
ATOM   7778  C  CG  . PRO B 1 513 ? 151.035 186.924 143.662 1.00 62.51  ? 513 PRO B CG  1 
ATOM   7779  C  CD  . PRO B 1 513 ? 150.200 187.292 142.472 1.00 62.51  ? 513 PRO B CD  1 
ATOM   7780  N  N   . ALA B 1 514 ? 148.910 189.621 144.977 1.00 65.61  ? 514 ALA B N   1 
ATOM   7781  C  CA  . ALA B 1 514 ? 148.821 190.774 145.866 1.00 65.61  ? 514 ALA B CA  1 
ATOM   7782  C  C   . ALA B 1 514 ? 147.398 191.317 145.921 1.00 65.61  ? 514 ALA B C   1 
ATOM   7783  O  O   . ALA B 1 514 ? 146.982 191.902 146.926 1.00 65.61  ? 514 ALA B O   1 
ATOM   7784  C  CB  . ALA B 1 514 ? 149.798 191.861 145.414 1.00 65.61  ? 514 ALA B CB  1 
ATOM   7785  N  N   . THR B 1 515 ? 146.636 191.127 144.846 1.00 69.43  ? 515 THR B N   1 
ATOM   7786  C  CA  . THR B 1 515 ? 145.271 191.627 144.754 1.00 69.43  ? 515 THR B CA  1 
ATOM   7787  C  C   . THR B 1 515 ? 144.242 190.518 144.585 1.00 69.43  ? 515 THR B C   1 
ATOM   7788  O  O   . THR B 1 515 ? 143.041 190.803 144.608 1.00 69.43  ? 515 THR B O   1 
ATOM   7789  C  CB  . THR B 1 515 ? 145.148 192.615 143.590 1.00 69.43  ? 515 THR B CB  1 
ATOM   7790  O  OG1 . THR B 1 515 ? 145.447 191.946 142.359 1.00 69.43  ? 515 THR B OG1 1 
ATOM   7791  C  CG2 . THR B 1 515 ? 146.113 193.774 143.771 1.00 69.43  ? 515 THR B CG2 1 
ATOM   7792  N  N   . SER B 1 516 ? 144.683 189.270 144.412 1.00 72.26  ? 516 SER B N   1 
ATOM   7793  C  CA  . SER B 1 516 ? 143.788 188.126 144.221 1.00 72.26  ? 516 SER B CA  1 
ATOM   7794  C  C   . SER B 1 516 ? 142.874 188.329 143.015 1.00 72.26  ? 516 SER B C   1 
ATOM   7795  O  O   . SER B 1 516 ? 141.730 187.872 142.995 1.00 72.26  ? 516 SER B O   1 
ATOM   7796  C  CB  . SER B 1 516 ? 142.971 187.844 145.483 1.00 72.26  ? 516 SER B CB  1 
ATOM   7797  O  OG  . SER B 1 516 ? 143.811 187.477 146.562 1.00 72.26  ? 516 SER B OG  1 
ATOM   7798  N  N   . ALA B 1 517 ? 143.385 189.017 141.997 1.00 74.94  ? 517 ALA B N   1 
ATOM   7799  C  CA  . ALA B 1 517 ? 142.624 189.331 140.790 1.00 74.94  ? 517 ALA B CA  1 
ATOM   7800  C  C   . ALA B 1 517 ? 142.825 188.201 139.789 1.00 74.94  ? 517 ALA B C   1 
ATOM   7801  O  O   . ALA B 1 517 ? 143.793 188.198 139.025 1.00 74.94  ? 517 ALA B O   1 
ATOM   7802  C  CB  . ALA B 1 517 ? 143.056 190.674 140.210 1.00 74.94  ? 517 ALA B CB  1 
ATOM   7803  N  N   . VAL B 1 518 ? 141.905 187.242 139.792 1.00 77.73  ? 518 VAL B N   1 
ATOM   7804  C  CA  . VAL B 1 518 ? 141.972 186.113 138.872 1.00 77.73  ? 518 VAL B CA  1 
ATOM   7805  C  C   . VAL B 1 518 ? 141.431 186.547 137.517 1.00 77.73  ? 518 VAL B C   1 
ATOM   7806  O  O   . VAL B 1 518 ? 140.219 186.724 137.345 1.00 77.73  ? 518 VAL B O   1 
ATOM   7807  C  CB  . VAL B 1 518 ? 141.189 184.913 139.427 1.00 77.73  ? 518 VAL B CB  1 
ATOM   7808  C  CG1 . VAL B 1 518 ? 141.189 183.772 138.429 1.00 77.73  ? 518 VAL B CG1 1 
ATOM   7809  C  CG2 . VAL B 1 518 ? 141.776 184.465 140.756 1.00 77.73  ? 518 VAL B CG2 1 
ATOM   7810  N  N   . THR B 1 519 ? 142.329 186.723 136.550 1.00 82.32  ? 519 THR B N   1 
ATOM   7811  C  CA  . THR B 1 519 ? 141.962 187.138 135.201 1.00 82.32  ? 519 THR B CA  1 
ATOM   7812  C  C   . THR B 1 519 ? 141.977 185.916 134.298 1.00 82.32  ? 519 THR B C   1 
ATOM   7813  O  O   . THR B 1 519 ? 142.152 184.791 134.776 1.00 82.32  ? 519 THR B O   1 
ATOM   7814  C  CB  . THR B 1 519 ? 142.913 188.214 134.666 1.00 82.32  ? 519 THR B CB  1 
ATOM   7815  O  OG1 . THR B 1 519 ? 142.408 188.727 133.428 1.00 82.32  ? 519 THR B OG1 1 
ATOM   7816  C  CG2 . THR B 1 519 ? 144.299 187.640 134.432 1.00 82.32  ? 519 THR B CG2 1 
ATOM   7817  N  N   . VAL B 1 520 ? 141.788 186.135 133.000 1.00 93.37  ? 520 VAL B N   1 
ATOM   7818  C  CA  . VAL B 1 520 ? 141.763 185.048 132.029 1.00 93.37  ? 520 VAL B CA  1 
ATOM   7819  C  C   . VAL B 1 520 ? 142.769 185.323 130.923 1.00 93.37  ? 520 VAL B C   1 
ATOM   7820  O  O   . VAL B 1 520 ? 142.698 186.354 130.247 1.00 93.37  ? 520 VAL B O   1 
ATOM   7821  C  CB  . VAL B 1 520 ? 140.353 184.858 131.444 1.00 93.37  ? 520 VAL B CB  1 
ATOM   7822  C  CG1 . VAL B 1 520 ? 140.398 183.868 130.301 1.00 93.37  ? 520 VAL B CG1 1 
ATOM   7823  C  CG2 . VAL B 1 520 ? 139.390 184.392 132.521 1.00 93.37  ? 520 VAL B CG2 1 
ATOM   7824  N  N   . THR B 1 521 ? 143.710 184.404 130.730 1.00 101.53 ? 521 THR B N   1 
ATOM   7825  C  CA  . THR B 1 521 ? 144.659 184.520 129.633 1.00 101.53 ? 521 THR B CA  1 
ATOM   7826  C  C   . THR B 1 521 ? 144.299 183.529 128.533 1.00 101.53 ? 521 THR B C   1 
ATOM   7827  O  O   . THR B 1 521 ? 143.787 182.439 128.806 1.00 101.53 ? 521 THR B O   1 
ATOM   7828  C  CB  . THR B 1 521 ? 146.089 184.295 130.128 1.00 101.53 ? 521 THR B CB  1 
ATOM   7829  O  OG1 . THR B 1 521 ? 147.010 184.514 129.052 1.00 101.53 ? 521 THR B OG1 1 
ATOM   7830  C  CG2 . THR B 1 521 ? 146.265 182.892 130.670 1.00 101.53 ? 521 THR B CG2 1 
ATOM   7831  N  N   . ARG B 1 522 ? 144.549 183.922 127.285 1.00 110.65 ? 522 ARG B N   1 
ATOM   7832  C  CA  . ARG B 1 522 ? 144.162 183.121 126.131 1.00 110.65 ? 522 ARG B CA  1 
ATOM   7833  C  C   . ARG B 1 522 ? 145.375 182.791 125.271 1.00 110.65 ? 522 ARG B C   1 
ATOM   7834  O  O   . ARG B 1 522 ? 146.457 183.350 125.475 1.00 110.65 ? 522 ARG B O   1 
ATOM   7835  C  CB  . ARG B 1 522 ? 143.115 183.862 125.295 1.00 110.65 ? 522 ARG B CB  1 
ATOM   7836  C  CG  . ARG B 1 522 ? 141.812 184.171 126.019 1.00 110.65 ? 522 ARG B CG  1 
ATOM   7837  C  CD  . ARG B 1 522 ? 140.985 182.918 126.251 1.00 110.65 ? 522 ARG B CD  1 
ATOM   7838  N  NE  . ARG B 1 522 ? 139.681 183.227 126.831 1.00 110.65 ? 522 ARG B NE  1 
ATOM   7839  C  CZ  . ARG B 1 522 ? 138.784 182.313 127.185 1.00 110.65 ? 522 ARG B CZ  1 
ATOM   7840  N  NH1 . ARG B 1 522 ? 139.048 181.024 127.021 1.00 110.65 ? 522 ARG B NH1 1 
ATOM   7841  N  NH2 . ARG B 1 522 ? 137.623 182.687 127.705 1.00 110.65 ? 522 ARG B NH2 1 
ATOM   7842  N  N   . GLY B 1 523 ? 145.204 181.890 124.309 1.00 113.64 ? 523 GLY B N   1 
ATOM   7843  C  CA  . GLY B 1 523 ? 146.262 181.580 123.364 1.00 113.64 ? 523 GLY B CA  1 
ATOM   7844  C  C   . GLY B 1 523 ? 146.927 180.233 123.562 1.00 113.64 ? 523 GLY B C   1 
ATOM   7845  O  O   . GLY B 1 523 ? 148.136 180.098 123.380 1.00 113.64 ? 523 GLY B O   1 
ATOM   7846  N  N   . ILE B 1 524 ? 146.133 179.226 123.936 1.00 115.48 ? 524 ILE B N   1 
ATOM   7847  C  CA  . ILE B 1 524 ? 146.674 177.884 124.108 1.00 115.48 ? 524 ILE B CA  1 
ATOM   7848  C  C   . ILE B 1 524 ? 146.912 177.212 122.761 1.00 115.48 ? 524 ILE B C   1 
ATOM   7849  O  O   . ILE B 1 524 ? 147.710 176.270 122.673 1.00 115.48 ? 524 ILE B O   1 
ATOM   7850  C  CB  . ILE B 1 524 ? 145.734 177.052 125.001 1.00 115.48 ? 524 ILE B CB  1 
ATOM   7851  C  CG1 . ILE B 1 524 ? 145.475 177.786 126.316 1.00 115.48 ? 524 ILE B CG1 1 
ATOM   7852  C  CG2 . ILE B 1 524 ? 146.337 175.689 125.311 1.00 115.48 ? 524 ILE B CG2 1 
ATOM   7853  C  CD1 . ILE B 1 524 ? 146.725 178.034 127.134 1.00 115.48 ? 524 ILE B CD1 1 
ATOM   7854  N  N   . LYS B 1 525 ? 146.244 177.682 121.706 1.00 114.42 ? 525 LYS B N   1 
ATOM   7855  C  CA  . LYS B 1 525 ? 146.461 177.194 120.342 1.00 114.42 ? 525 LYS B CA  1 
ATOM   7856  C  C   . LYS B 1 525 ? 146.149 175.703 120.226 1.00 114.42 ? 525 LYS B C   1 
ATOM   7857  O  O   . LYS B 1 525 ? 145.037 175.308 119.871 1.00 114.42 ? 525 LYS B O   1 
ATOM   7858  C  CB  . LYS B 1 525 ? 147.886 177.495 119.870 1.00 114.42 ? 525 LYS B CB  1 
ATOM   7859  C  CG  . LYS B 1 525 ? 148.185 178.981 119.724 1.00 114.42 ? 525 LYS B CG  1 
ATOM   7860  C  CD  . LYS B 1 525 ? 149.612 179.222 119.259 1.00 114.42 ? 525 LYS B CD  1 
ATOM   7861  C  CE  . LYS B 1 525 ? 149.917 180.709 119.154 1.00 114.42 ? 525 LYS B CE  1 
ATOM   7862  N  NZ  . LYS B 1 525 ? 151.319 180.959 118.720 1.00 114.42 ? 525 LYS B NZ  1 
ATOM   7863  N  N   . VAL B 1 526 ? 147.142 174.866 120.528 1.00 113.68 ? 526 VAL B N   1 
ATOM   7864  C  CA  . VAL B 1 526 ? 147.003 173.416 120.464 1.00 113.68 ? 526 VAL B CA  1 
ATOM   7865  C  C   . VAL B 1 526 ? 146.444 172.910 121.790 1.00 113.68 ? 526 VAL B C   1 
ATOM   7866  O  O   . VAL B 1 526 ? 147.157 172.358 122.631 1.00 113.68 ? 526 VAL B O   1 
ATOM   7867  C  CB  . VAL B 1 526 ? 148.336 172.719 120.106 1.00 113.68 ? 526 VAL B CB  1 
ATOM   7868  C  CG1 . VAL B 1 526 ? 148.673 172.972 118.648 1.00 113.68 ? 526 VAL B CG1 1 
ATOM   7869  C  CG2 . VAL B 1 526 ? 149.470 173.248 120.971 1.00 113.68 ? 526 VAL B CG2 1 
ATOM   7870  N  N   . LEU B 1 527 ? 145.138 173.099 121.960 1.00 116.72 ? 527 LEU B N   1 
ATOM   7871  C  CA  . LEU B 1 527 ? 144.418 172.718 123.171 1.00 116.72 ? 527 LEU B CA  1 
ATOM   7872  C  C   . LEU B 1 527 ? 144.525 171.221 123.447 1.00 116.72 ? 527 LEU B C   1 
ATOM   7873  O  O   . LEU B 1 527 ? 144.515 170.398 122.530 1.00 116.72 ? 527 LEU B O   1 
ATOM   7874  C  CB  . LEU B 1 527 ? 142.950 173.132 123.081 1.00 116.72 ? 527 LEU B CB  1 
ATOM   7875  C  CG  . LEU B 1 527 ? 142.550 174.548 123.508 1.00 116.72 ? 527 LEU B CG  1 
ATOM   7876  C  CD1 . LEU B 1 527 ? 142.820 174.758 124.990 1.00 116.72 ? 527 LEU B CD1 1 
ATOM   7877  C  CD2 . LEU B 1 527 ? 143.243 175.615 122.670 1.00 116.72 ? 527 LEU B CD2 1 
ATOM   7878  N  N   . LEU B 1 528 ? 144.632 170.860 124.722 1.00 110.36 ? 528 LEU B N   1 
ATOM   7879  C  CA  . LEU B 1 528 ? 144.640 169.463 125.121 1.00 110.36 ? 528 LEU B CA  1 
ATOM   7880  C  C   . LEU B 1 528 ? 143.258 169.061 125.621 1.00 110.36 ? 528 LEU B C   1 
ATOM   7881  O  O   . LEU B 1 528 ? 142.235 169.583 125.169 1.00 110.36 ? 528 LEU B O   1 
ATOM   7882  C  CB  . LEU B 1 528 ? 145.691 169.215 126.207 1.00 110.36 ? 528 LEU B CB  1 
ATOM   7883  C  CG  . LEU B 1 528 ? 147.163 169.125 125.787 1.00 110.36 ? 528 LEU B CG  1 
ATOM   7884  C  CD1 . LEU B 1 528 ? 147.728 170.487 125.412 1.00 110.36 ? 528 LEU B CD1 1 
ATOM   7885  C  CD2 . LEU B 1 528 ? 147.992 168.501 126.891 1.00 110.36 ? 528 LEU B CD2 1 
ATOM   7886  N  N   . THR B 1 529 ? 143.235 168.128 126.570 1.00 110.82 ? 529 THR B N   1 
ATOM   7887  C  CA  . THR B 1 529 ? 141.971 167.692 127.150 1.00 110.82 ? 529 THR B CA  1 
ATOM   7888  C  C   . THR B 1 529 ? 142.119 167.016 128.504 1.00 110.82 ? 529 THR B C   1 
ATOM   7889  O  O   . THR B 1 529 ? 141.114 166.872 129.204 1.00 110.82 ? 529 THR B O   1 
ATOM   7890  C  CB  . THR B 1 529 ? 141.244 166.737 126.191 1.00 110.82 ? 529 THR B CB  1 
ATOM   7891  O  OG1 . THR B 1 529 ? 139.927 166.473 126.689 1.00 110.82 ? 529 THR B OG1 1 
ATOM   7892  C  CG2 . THR B 1 529 ? 142.001 165.430 126.086 1.00 110.82 ? 529 THR B CG2 1 
ATOM   7893  N  N   . ASN B 1 530 ? 143.316 166.590 128.897 1.00 102.83 ? 530 ASN B N   1 
ATOM   7894  C  CA  . ASN B 1 530 ? 143.519 165.904 130.166 1.00 102.83 ? 530 ASN B CA  1 
ATOM   7895  C  C   . ASN B 1 530 ? 144.912 166.133 130.724 1.00 102.83 ? 530 ASN B C   1 
ATOM   7896  O  O   . ASN B 1 530 ? 145.820 165.340 130.454 1.00 102.83 ? 530 ASN B O   1 
ATOM   7897  C  CB  . ASN B 1 530 ? 143.259 164.399 129.997 1.00 102.83 ? 530 ASN B CB  1 
ATOM   7898  C  CG  . ASN B 1 530 ? 143.205 163.660 131.320 1.00 102.83 ? 530 ASN B CG  1 
ATOM   7899  O  OD1 . ASN B 1 530 ? 143.365 164.253 132.388 1.00 102.83 ? 530 ASN B OD1 1 
ATOM   7900  N  ND2 . ASN B 1 530 ? 142.979 162.354 131.255 1.00 102.83 ? 530 ASN B ND2 1 
ATOM   7901  N  N   . LEU B 1 531 ? 145.110 167.200 131.496 1.00 89.10  ? 531 LEU B N   1 
ATOM   7902  C  CA  . LEU B 1 531 ? 146.417 167.549 132.048 1.00 89.10  ? 531 LEU B CA  1 
ATOM   7903  C  C   . LEU B 1 531 ? 146.822 166.562 133.147 1.00 89.10  ? 531 LEU B C   1 
ATOM   7904  O  O   . LEU B 1 531 ? 146.159 166.408 134.173 1.00 89.10  ? 531 LEU B O   1 
ATOM   7905  C  CB  . LEU B 1 531 ? 146.424 168.987 132.580 1.00 89.10  ? 531 LEU B CB  1 
ATOM   7906  C  CG  . LEU B 1 531 ? 146.752 170.106 131.592 1.00 89.10  ? 531 LEU B CG  1 
ATOM   7907  C  CD1 . LEU B 1 531 ? 148.170 169.966 131.071 1.00 89.10  ? 531 LEU B CD1 1 
ATOM   7908  C  CD2 . LEU B 1 531 ? 145.769 170.110 130.447 1.00 89.10  ? 531 LEU B CD2 1 
ATOM   7909  N  N   . GLN B 1 532 ? 147.947 165.895 132.894 1.00 77.64  ? 532 GLN B N   1 
ATOM   7910  C  CA  . GLN B 1 532 ? 148.543 165.047 133.920 1.00 77.64  ? 532 GLN B CA  1 
ATOM   7911  C  C   . GLN B 1 532 ? 149.544 165.836 134.750 1.00 77.64  ? 532 GLN B C   1 
ATOM   7912  O  O   . GLN B 1 532 ? 149.517 165.797 135.985 1.00 77.64  ? 532 GLN B O   1 
ATOM   7913  C  CB  . GLN B 1 532 ? 149.219 163.836 133.277 1.00 77.64  ? 532 GLN B CB  1 
ATOM   7914  C  CG  . GLN B 1 532 ? 148.266 162.872 132.602 1.00 77.64  ? 532 GLN B CG  1 
ATOM   7915  C  CD  . GLN B 1 532 ? 148.986 161.714 131.943 1.00 77.64  ? 532 GLN B CD  1 
ATOM   7916  O  OE1 . GLN B 1 532 ? 150.215 161.657 131.935 1.00 77.64  ? 532 GLN B OE1 1 
ATOM   7917  N  NE2 . GLN B 1 532 ? 148.223 160.784 131.381 1.00 77.64  ? 532 GLN B NE2 1 
ATOM   7918  N  N   . PHE B 1 533 ? 150.427 166.574 134.083 1.00 66.09  ? 533 PHE B N   1 
ATOM   7919  C  CA  . PHE B 1 533 ? 151.491 167.302 134.748 1.00 66.09  ? 533 PHE B CA  1 
ATOM   7920  C  C   . PHE B 1 533 ? 151.589 168.701 134.160 1.00 66.09  ? 533 PHE B C   1 
ATOM   7921  O  O   . PHE B 1 533 ? 151.647 168.876 132.941 1.00 66.09  ? 533 PHE B O   1 
ATOM   7922  C  CB  . PHE B 1 533 ? 152.836 166.578 134.605 1.00 66.09  ? 533 PHE B CB  1 
ATOM   7923  C  CG  . PHE B 1 533 ? 152.858 165.214 135.232 1.00 66.09  ? 533 PHE B CG  1 
ATOM   7924  C  CD1 . PHE B 1 533 ? 153.012 165.064 136.597 1.00 66.09  ? 533 PHE B CD1 1 
ATOM   7925  C  CD2 . PHE B 1 533 ? 152.726 164.081 134.452 1.00 66.09  ? 533 PHE B CD2 1 
ATOM   7926  C  CE1 . PHE B 1 533 ? 153.028 163.810 137.171 1.00 66.09  ? 533 PHE B CE1 1 
ATOM   7927  C  CE2 . PHE B 1 533 ? 152.744 162.827 135.022 1.00 66.09  ? 533 PHE B CE2 1 
ATOM   7928  C  CZ  . PHE B 1 533 ? 152.894 162.691 136.381 1.00 66.09  ? 533 PHE B CZ  1 
ATOM   7929  N  N   . VAL B 1 534 ? 151.594 169.695 135.043 1.00 69.10  ? 534 VAL B N   1 
ATOM   7930  C  CA  . VAL B 1 534 ? 151.841 171.084 134.676 1.00 69.10  ? 534 VAL B CA  1 
ATOM   7931  C  C   . VAL B 1 534 ? 153.077 171.530 135.439 1.00 69.10  ? 534 VAL B C   1 
ATOM   7932  O  O   . VAL B 1 534 ? 152.983 171.903 136.614 1.00 69.10  ? 534 VAL B O   1 
ATOM   7933  C  CB  . VAL B 1 534 ? 150.648 171.997 134.995 1.00 69.10  ? 534 VAL B CB  1 
ATOM   7934  C  CG1 . VAL B 1 534 ? 150.984 173.437 134.643 1.00 69.10  ? 534 VAL B CG1 1 
ATOM   7935  C  CG2 . VAL B 1 534 ? 149.411 171.532 134.250 1.00 69.10  ? 534 VAL B CG2 1 
ATOM   7936  N  N   . LEU B 1 535 ? 154.227 171.487 134.779 1.00 68.02  ? 535 LEU B N   1 
ATOM   7937  C  CA  . LEU B 1 535 ? 155.517 171.642 135.435 1.00 68.02  ? 535 LEU B CA  1 
ATOM   7938  C  C   . LEU B 1 535 ? 155.880 173.117 135.527 1.00 68.02  ? 535 LEU B C   1 
ATOM   7939  O  O   . LEU B 1 535 ? 155.126 173.976 135.061 1.00 68.02  ? 535 LEU B O   1 
ATOM   7940  C  CB  . LEU B 1 535 ? 156.595 170.865 134.683 1.00 68.02  ? 535 LEU B CB  1 
ATOM   7941  C  CG  . LEU B 1 535 ? 156.321 169.362 134.679 1.00 68.02  ? 535 LEU B CG  1 
ATOM   7942  C  CD1 . LEU B 1 535 ? 157.347 168.633 133.848 1.00 68.02  ? 535 LEU B CD1 1 
ATOM   7943  C  CD2 . LEU B 1 535 ? 156.287 168.825 136.098 1.00 68.02  ? 535 LEU B CD2 1 
ATOM   7944  N  N   . ALA B 1 536 ? 157.025 173.401 136.137 1.00 70.30  ? 536 ALA B N   1 
ATOM   7945  C  CA  . ALA B 1 536 ? 157.455 174.773 136.375 1.00 70.30  ? 536 ALA B CA  1 
ATOM   7946  C  C   . ALA B 1 536 ? 157.738 175.504 135.071 1.00 70.30  ? 536 ALA B C   1 
ATOM   7947  O  O   . ALA B 1 536 ? 157.848 176.729 135.052 1.00 70.30  ? 536 ALA B O   1 
ATOM   7948  C  CB  . ALA B 1 536 ? 158.687 174.790 137.268 1.00 70.30  ? 536 ALA B CB  1 
ATOM   7949  N  N   . ARG C 2 8   ? 189.728 121.197 125.033 1.00 89.35  ? 8   ARG C N   1 
ATOM   7950  C  CA  . ARG C 2 8   ? 189.352 120.024 124.253 1.00 89.35  ? 8   ARG C CA  1 
ATOM   7951  C  C   . ARG C 2 8   ? 188.031 119.456 124.756 1.00 89.35  ? 8   ARG C C   1 
ATOM   7952  O  O   . ARG C 2 8   ? 187.984 118.367 125.327 1.00 89.35  ? 8   ARG C O   1 
ATOM   7953  C  CB  . ARG C 2 8   ? 190.454 118.965 124.315 1.00 89.35  ? 8   ARG C CB  1 
ATOM   7954  C  CG  . ARG C 2 8   ? 191.744 119.397 123.638 1.00 89.35  ? 8   ARG C CG  1 
ATOM   7955  C  CD  . ARG C 2 8   ? 192.825 118.334 123.737 1.00 89.35  ? 8   ARG C CD  1 
ATOM   7956  N  NE  . ARG C 2 8   ? 194.071 118.779 123.119 1.00 89.35  ? 8   ARG C NE  1 
ATOM   7957  C  CZ  . ARG C 2 8   ? 195.200 118.078 123.115 1.00 89.35  ? 8   ARG C CZ  1 
ATOM   7958  N  NH1 . ARG C 2 8   ? 195.247 116.888 123.698 1.00 89.35  ? 8   ARG C NH1 1 
ATOM   7959  N  NH2 . ARG C 2 8   ? 196.283 118.568 122.527 1.00 89.35  ? 8   ARG C NH2 1 
ATOM   7960  N  N   . ARG C 2 9   ? 186.958 120.209 124.535 1.00 75.72  ? 9   ARG C N   1 
ATOM   7961  C  CA  . ARG C 2 9   ? 185.641 119.832 125.017 1.00 75.72  ? 9   ARG C CA  1 
ATOM   7962  C  C   . ARG C 2 9   ? 184.571 120.192 123.990 1.00 75.72  ? 9   ARG C C   1 
ATOM   7963  O  O   . ARG C 2 9   ? 184.492 121.322 123.502 1.00 75.72  ? 9   ARG C O   1 
ATOM   7964  C  CB  . ARG C 2 9   ? 185.353 120.514 126.354 1.00 75.72  ? 9   ARG C CB  1 
ATOM   7965  C  CG  . ARG C 2 9   ? 184.035 120.124 126.989 1.00 75.72  ? 9   ARG C CG  1 
ATOM   7966  C  CD  . ARG C 2 9   ? 183.889 120.768 128.354 1.00 75.72  ? 9   ARG C CD  1 
ATOM   7967  N  NE  . ARG C 2 9   ? 184.863 120.243 129.305 1.00 75.72  ? 9   ARG C NE  1 
ATOM   7968  C  CZ  . ARG C 2 9   ? 185.873 120.944 129.807 1.00 75.72  ? 9   ARG C CZ  1 
ATOM   7969  N  NH1 . ARG C 2 9   ? 186.051 122.207 129.446 1.00 75.72  ? 9   ARG C NH1 1 
ATOM   7970  N  NH2 . ARG C 2 9   ? 186.709 120.381 130.669 1.00 75.72  ? 9   ARG C NH2 1 
ATOM   7971  N  N   . LYS C 2 10  ? 183.742 119.205 123.664 1.00 68.00  ? 10  LYS C N   1 
ATOM   7972  C  CA  . LYS C 2 10  ? 182.729 119.333 122.625 1.00 68.00  ? 10  LYS C CA  1 
ATOM   7973  C  C   . LYS C 2 10  ? 181.670 120.338 123.055 1.00 68.00  ? 10  LYS C C   1 
ATOM   7974  O  O   . LYS C 2 10  ? 181.220 120.320 124.205 1.00 68.00  ? 10  LYS C O   1 
ATOM   7975  C  CB  . LYS C 2 10  ? 182.090 117.975 122.330 1.00 68.00  ? 10  LYS C CB  1 
ATOM   7976  C  CG  . LYS C 2 10  ? 181.145 117.969 121.144 1.00 68.00  ? 10  LYS C CG  1 
ATOM   7977  C  CD  . LYS C 2 10  ? 180.537 116.591 120.943 1.00 68.00  ? 10  LYS C CD  1 
ATOM   7978  C  CE  . LYS C 2 10  ? 181.550 115.618 120.368 1.00 68.00  ? 10  LYS C CE  1 
ATOM   7979  N  NZ  . LYS C 2 10  ? 180.937 114.295 120.067 1.00 68.00  ? 10  LYS C NZ  1 
ATOM   7980  N  N   . VAL C 2 11  ? 181.281 121.216 122.132 1.00 59.08  ? 11  VAL C N   1 
ATOM   7981  C  CA  . VAL C 2 11  ? 180.310 122.272 122.395 1.00 59.08  ? 11  VAL C CA  1 
ATOM   7982  C  C   . VAL C 2 11  ? 179.273 122.264 121.280 1.00 59.08  ? 11  VAL C C   1 
ATOM   7983  O  O   . VAL C 2 11  ? 179.626 122.258 120.094 1.00 59.08  ? 11  VAL C O   1 
ATOM   7984  C  CB  . VAL C 2 11  ? 180.985 123.652 122.500 1.00 59.08  ? 11  VAL C CB  1 
ATOM   7985  C  CG1 . VAL C 2 11  ? 179.944 124.741 122.693 1.00 59.08  ? 11  VAL C CG1 1 
ATOM   7986  C  CG2 . VAL C 2 11  ? 181.995 123.669 123.633 1.00 59.08  ? 11  VAL C CG2 1 
ATOM   7987  N  N   . CYS C 2 12  ? 177.998 122.258 121.661 1.00 55.77  ? 12  CYS C N   1 
ATOM   7988  C  CA  . CYS C 2 12  ? 176.897 122.373 120.720 1.00 55.77  ? 12  CYS C CA  1 
ATOM   7989  C  C   . CYS C 2 12  ? 176.244 123.738 120.878 1.00 55.77  ? 12  CYS C C   1 
ATOM   7990  O  O   . CYS C 2 12  ? 176.470 124.438 121.867 1.00 55.77  ? 12  CYS C O   1 
ATOM   7991  C  CB  . CYS C 2 12  ? 175.858 121.275 120.929 1.00 55.77  ? 12  CYS C CB  1 
ATOM   7992  S  SG  . CYS C 2 12  ? 174.988 121.384 122.489 1.00 55.77  ? 12  CYS C SG  1 
ATOM   7993  N  N   . TYR C 2 13  ? 175.422 124.107 119.900 1.00 51.70  ? 13  TYR C N   1 
ATOM   7994  C  CA  . TYR C 2 13  ? 174.855 125.444 119.813 1.00 51.70  ? 13  TYR C CA  1 
ATOM   7995  C  C   . TYR C 2 13  ? 173.507 125.399 119.110 1.00 51.70  ? 13  TYR C C   1 
ATOM   7996  O  O   . TYR C 2 13  ? 173.411 124.954 117.966 1.00 51.70  ? 13  TYR C O   1 
ATOM   7997  C  CB  . TYR C 2 13  ? 175.808 126.375 119.068 1.00 51.70  ? 13  TYR C CB  1 
ATOM   7998  C  CG  . TYR C 2 13  ? 175.314 127.789 118.919 1.00 51.70  ? 13  TYR C CG  1 
ATOM   7999  C  CD1 . TYR C 2 13  ? 175.300 128.655 119.996 1.00 51.70  ? 13  TYR C CD1 1 
ATOM   8000  C  CD2 . TYR C 2 13  ? 174.880 128.265 117.693 1.00 51.70  ? 13  TYR C CD2 1 
ATOM   8001  C  CE1 . TYR C 2 13  ? 174.852 129.950 119.862 1.00 51.70  ? 13  TYR C CE1 1 
ATOM   8002  C  CE2 . TYR C 2 13  ? 174.436 129.558 117.549 1.00 51.70  ? 13  TYR C CE2 1 
ATOM   8003  C  CZ  . TYR C 2 13  ? 174.423 130.395 118.637 1.00 51.70  ? 13  TYR C CZ  1 
ATOM   8004  O  OH  . TYR C 2 13  ? 173.978 131.687 118.504 1.00 51.70  ? 13  TYR C OH  1 
ATOM   8005  N  N   . TYR C 2 14  ? 172.472 125.873 119.797 1.00 52.14  ? 14  TYR C N   1 
ATOM   8006  C  CA  . TYR C 2 14  ? 171.098 125.844 119.298 1.00 52.14  ? 14  TYR C CA  1 
ATOM   8007  C  C   . TYR C 2 14  ? 170.692 127.238 118.833 1.00 52.14  ? 14  TYR C C   1 
ATOM   8008  O  O   . TYR C 2 14  ? 170.720 128.195 119.614 1.00 52.14  ? 14  TYR C O   1 
ATOM   8009  C  CB  . TYR C 2 14  ? 170.151 125.324 120.370 1.00 52.14  ? 14  TYR C CB  1 
ATOM   8010  C  CG  . TYR C 2 14  ? 170.233 123.833 120.567 1.00 52.14  ? 14  TYR C CG  1 
ATOM   8011  C  CD1 . TYR C 2 14  ? 169.494 122.975 119.769 1.00 52.14  ? 14  TYR C CD1 1 
ATOM   8012  C  CD2 . TYR C 2 14  ? 171.066 123.280 121.525 1.00 52.14  ? 14  TYR C CD2 1 
ATOM   8013  C  CE1 . TYR C 2 14  ? 169.562 121.614 119.932 1.00 52.14  ? 14  TYR C CE1 1 
ATOM   8014  C  CE2 . TYR C 2 14  ? 171.145 121.915 121.692 1.00 52.14  ? 14  TYR C CE2 1 
ATOM   8015  C  CZ  . TYR C 2 14  ? 170.389 121.088 120.891 1.00 52.14  ? 14  TYR C CZ  1 
ATOM   8016  O  OH  . TYR C 2 14  ? 170.452 119.727 121.047 1.00 52.14  ? 14  TYR C OH  1 
ATOM   8017  N  N   . TYR C 2 15  ? 170.300 127.344 117.565 1.00 58.65  ? 15  TYR C N   1 
ATOM   8018  C  CA  . TYR C 2 15  ? 169.884 128.607 116.976 1.00 58.65  ? 15  TYR C CA  1 
ATOM   8019  C  C   . TYR C 2 15  ? 169.060 128.358 115.725 1.00 58.65  ? 15  TYR C C   1 
ATOM   8020  O  O   . TYR C 2 15  ? 169.567 127.821 114.738 1.00 58.65  ? 15  TYR C O   1 
ATOM   8021  C  CB  . TYR C 2 15  ? 171.085 129.484 116.619 1.00 58.65  ? 15  TYR C CB  1 
ATOM   8022  C  CG  . TYR C 2 15  ? 170.701 130.746 115.886 1.00 58.65  ? 15  TYR C CG  1 
ATOM   8023  C  CD1 . TYR C 2 15  ? 170.090 131.801 116.548 1.00 58.65  ? 15  TYR C CD1 1 
ATOM   8024  C  CD2 . TYR C 2 15  ? 170.950 130.883 114.529 1.00 58.65  ? 15  TYR C CD2 1 
ATOM   8025  C  CE1 . TYR C 2 15  ? 169.735 132.953 115.878 1.00 58.65  ? 15  TYR C CE1 1 
ATOM   8026  C  CE2 . TYR C 2 15  ? 170.600 132.031 113.853 1.00 58.65  ? 15  TYR C CE2 1 
ATOM   8027  C  CZ  . TYR C 2 15  ? 169.993 133.062 114.532 1.00 58.65  ? 15  TYR C CZ  1 
ATOM   8028  O  OH  . TYR C 2 15  ? 169.642 134.208 113.860 1.00 58.65  ? 15  TYR C OH  1 
ATOM   8029  N  N   . ASP C 2 16  ? 167.794 128.765 115.769 1.00 63.36  ? 16  ASP C N   1 
ATOM   8030  C  CA  . ASP C 2 16  ? 166.912 128.741 114.612 1.00 63.36  ? 16  ASP C CA  1 
ATOM   8031  C  C   . ASP C 2 16  ? 166.897 130.123 113.980 1.00 63.36  ? 16  ASP C C   1 
ATOM   8032  O  O   . ASP C 2 16  ? 166.480 131.095 114.618 1.00 63.36  ? 16  ASP C O   1 
ATOM   8033  C  CB  . ASP C 2 16  ? 165.492 128.329 115.002 1.00 63.36  ? 16  ASP C CB  1 
ATOM   8034  C  CG  . ASP C 2 16  ? 164.605 128.072 113.798 1.00 63.36  ? 16  ASP C CG  1 
ATOM   8035  O  OD1 . ASP C 2 16  ? 165.091 128.211 112.656 1.00 63.36  ? 16  ASP C OD1 1 
ATOM   8036  O  OD2 . ASP C 2 16  ? 163.417 127.736 113.989 1.00 63.36  ? 16  ASP C OD2 1 
ATOM   8037  N  N   . GLY C 2 17  ? 167.344 130.210 112.728 1.00 64.71  ? 17  GLY C N   1 
ATOM   8038  C  CA  . GLY C 2 17  ? 167.342 131.481 112.025 1.00 64.71  ? 17  GLY C CA  1 
ATOM   8039  C  C   . GLY C 2 17  ? 165.966 132.060 111.778 1.00 64.71  ? 17  GLY C C   1 
ATOM   8040  O  O   . GLY C 2 17  ? 165.587 132.233 110.615 1.00 64.71  ? 17  GLY C O   1 
ATOM   8041  N  N   . ASP C 2 18  ? 165.219 132.369 112.835 1.00 64.51  ? 18  ASP C N   1 
ATOM   8042  C  CA  . ASP C 2 18  ? 163.837 132.808 112.723 1.00 64.51  ? 18  ASP C CA  1 
ATOM   8043  C  C   . ASP C 2 18  ? 163.319 133.414 114.021 1.00 64.51  ? 18  ASP C C   1 
ATOM   8044  O  O   . ASP C 2 18  ? 162.163 133.842 114.078 1.00 64.51  ? 18  ASP C O   1 
ATOM   8045  C  CB  . ASP C 2 18  ? 162.954 131.623 112.307 1.00 64.51  ? 18  ASP C CB  1 
ATOM   8046  C  CG  . ASP C 2 18  ? 161.613 132.051 111.740 1.00 64.51  ? 18  ASP C CG  1 
ATOM   8047  O  OD1 . ASP C 2 18  ? 161.370 133.269 111.614 1.00 64.51  ? 18  ASP C OD1 1 
ATOM   8048  O  OD2 . ASP C 2 18  ? 160.795 131.161 111.423 1.00 64.51  ? 18  ASP C OD2 1 
ATOM   8049  N  N   . VAL C 2 19  ? 164.149 133.464 115.066 1.00 61.73  ? 19  VAL C N   1 
ATOM   8050  C  CA  . VAL C 2 19  ? 163.696 133.979 116.351 1.00 61.73  ? 19  VAL C CA  1 
ATOM   8051  C  C   . VAL C 2 19  ? 163.763 135.498 116.406 1.00 61.73  ? 19  VAL C C   1 
ATOM   8052  O  O   . VAL C 2 19  ? 162.943 136.125 117.084 1.00 61.73  ? 19  VAL C O   1 
ATOM   8053  C  CB  . VAL C 2 19  ? 164.510 133.342 117.495 1.00 61.73  ? 19  VAL C CB  1 
ATOM   8054  C  CG1 . VAL C 2 19  ? 165.975 133.744 117.411 1.00 61.73  ? 19  VAL C CG1 1 
ATOM   8055  C  CG2 . VAL C 2 19  ? 163.920 133.711 118.847 1.00 61.73  ? 19  VAL C CG2 1 
ATOM   8056  N  N   . GLY C 2 20  ? 164.703 136.114 115.698 1.00 60.64  ? 20  GLY C N   1 
ATOM   8057  C  CA  . GLY C 2 20  ? 164.818 137.555 115.715 1.00 60.64  ? 20  GLY C CA  1 
ATOM   8058  C  C   . GLY C 2 20  ? 163.851 138.302 114.828 1.00 60.64  ? 20  GLY C C   1 
ATOM   8059  O  O   . GLY C 2 20  ? 164.131 139.441 114.447 1.00 60.64  ? 20  GLY C O   1 
ATOM   8060  N  N   . ASN C 2 21  ? 162.720 137.694 114.481 1.00 63.09  ? 21  ASN C N   1 
ATOM   8061  C  CA  . ASN C 2 21  ? 161.689 138.351 113.693 1.00 63.09  ? 21  ASN C CA  1 
ATOM   8062  C  C   . ASN C 2 21  ? 160.422 138.599 114.493 1.00 63.09  ? 21  ASN C C   1 
ATOM   8063  O  O   . ASN C 2 21  ? 159.542 139.332 114.032 1.00 63.09  ? 21  ASN C O   1 
ATOM   8064  C  CB  . ASN C 2 21  ? 161.366 137.523 112.450 1.00 63.09  ? 21  ASN C CB  1 
ATOM   8065  C  CG  . ASN C 2 21  ? 162.514 137.480 111.472 1.00 63.09  ? 21  ASN C CG  1 
ATOM   8066  O  OD1 . ASN C 2 21  ? 163.203 138.476 111.266 1.00 63.09  ? 21  ASN C OD1 1 
ATOM   8067  N  ND2 . ASN C 2 21  ? 162.722 136.325 110.854 1.00 63.09  ? 21  ASN C ND2 1 
ATOM   8068  N  N   . TYR C 2 22  ? 160.307 138.004 115.675 1.00 60.89  ? 22  TYR C N   1 
ATOM   8069  C  CA  . TYR C 2 22  ? 159.144 138.179 116.531 1.00 60.89  ? 22  TYR C CA  1 
ATOM   8070  C  C   . TYR C 2 22  ? 159.315 139.458 117.335 1.00 60.89  ? 22  TYR C C   1 
ATOM   8071  O  O   . TYR C 2 22  ? 160.220 139.559 118.169 1.00 60.89  ? 22  TYR C O   1 
ATOM   8072  C  CB  . TYR C 2 22  ? 158.961 136.974 117.450 1.00 60.89  ? 22  TYR C CB  1 
ATOM   8073  C  CG  . TYR C 2 22  ? 158.687 135.705 116.681 1.00 60.89  ? 22  TYR C CG  1 
ATOM   8074  C  CD1 . TYR C 2 22  ? 157.422 135.431 116.186 1.00 60.89  ? 22  TYR C CD1 1 
ATOM   8075  C  CD2 . TYR C 2 22  ? 159.698 134.793 116.430 1.00 60.89  ? 22  TYR C CD2 1 
ATOM   8076  C  CE1 . TYR C 2 22  ? 157.170 134.278 115.473 1.00 60.89  ? 22  TYR C CE1 1 
ATOM   8077  C  CE2 . TYR C 2 22  ? 159.455 133.636 115.719 1.00 60.89  ? 22  TYR C CE2 1 
ATOM   8078  C  CZ  . TYR C 2 22  ? 158.191 133.384 115.243 1.00 60.89  ? 22  TYR C CZ  1 
ATOM   8079  O  OH  . TYR C 2 22  ? 157.949 132.231 114.534 1.00 60.89  ? 22  TYR C OH  1 
ATOM   8080  N  N   . TYR C 2 23  ? 158.447 140.429 117.075 1.00 60.83  ? 23  TYR C N   1 
ATOM   8081  C  CA  . TYR C 2 23  ? 158.560 141.776 117.611 1.00 60.83  ? 23  TYR C CA  1 
ATOM   8082  C  C   . TYR C 2 23  ? 157.422 142.014 118.590 1.00 60.83  ? 23  TYR C C   1 
ATOM   8083  O  O   . TYR C 2 23  ? 156.252 142.016 118.192 1.00 60.83  ? 23  TYR C O   1 
ATOM   8084  C  CB  . TYR C 2 23  ? 158.523 142.794 116.470 1.00 60.83  ? 23  TYR C CB  1 
ATOM   8085  C  CG  . TYR C 2 23  ? 158.707 144.233 116.879 1.00 60.83  ? 23  TYR C CG  1 
ATOM   8086  C  CD1 . TYR C 2 23  ? 159.954 144.713 117.253 1.00 60.83  ? 23  TYR C CD1 1 
ATOM   8087  C  CD2 . TYR C 2 23  ? 157.640 145.122 116.860 1.00 60.83  ? 23  TYR C CD2 1 
ATOM   8088  C  CE1 . TYR C 2 23  ? 160.133 146.028 117.615 1.00 60.83  ? 23  TYR C CE1 1 
ATOM   8089  C  CE2 . TYR C 2 23  ? 157.810 146.444 117.222 1.00 60.83  ? 23  TYR C CE2 1 
ATOM   8090  C  CZ  . TYR C 2 23  ? 159.060 146.888 117.598 1.00 60.83  ? 23  TYR C CZ  1 
ATOM   8091  O  OH  . TYR C 2 23  ? 159.244 148.198 117.960 1.00 60.83  ? 23  TYR C OH  1 
ATOM   8092  N  N   . TYR C 2 24  ? 157.762 142.201 119.866 1.00 60.37  ? 24  TYR C N   1 
ATOM   8093  C  CA  . TYR C 2 24  ? 156.748 142.370 120.900 1.00 60.37  ? 24  TYR C CA  1 
ATOM   8094  C  C   . TYR C 2 24  ? 155.830 143.558 120.651 1.00 60.37  ? 24  TYR C C   1 
ATOM   8095  O  O   . TYR C 2 24  ? 154.660 143.353 120.315 1.00 60.37  ? 24  TYR C O   1 
ATOM   8096  C  CB  . TYR C 2 24  ? 157.398 142.528 122.276 1.00 60.37  ? 24  TYR C CB  1 
ATOM   8097  C  CG  . TYR C 2 24  ? 158.021 141.266 122.832 1.00 60.37  ? 24  TYR C CG  1 
ATOM   8098  C  CD1 . TYR C 2 24  ? 157.865 140.045 122.197 1.00 60.37  ? 24  TYR C CD1 1 
ATOM   8099  C  CD2 . TYR C 2 24  ? 158.722 141.293 124.025 1.00 60.37  ? 24  TYR C CD2 1 
ATOM   8100  C  CE1 . TYR C 2 24  ? 158.428 138.895 122.722 1.00 60.37  ? 24  TYR C CE1 1 
ATOM   8101  C  CE2 . TYR C 2 24  ? 159.277 140.155 124.557 1.00 60.37  ? 24  TYR C CE2 1 
ATOM   8102  C  CZ  . TYR C 2 24  ? 159.129 138.960 123.903 1.00 60.37  ? 24  TYR C CZ  1 
ATOM   8103  O  OH  . TYR C 2 24  ? 159.689 137.825 124.438 1.00 60.37  ? 24  TYR C OH  1 
ATOM   8104  N  N   . GLY C 2 25  ? 156.319 144.775 120.808 1.00 62.12  ? 25  GLY C N   1 
ATOM   8105  C  CA  . GLY C 2 25  ? 155.521 145.955 120.565 1.00 62.12  ? 25  GLY C CA  1 
ATOM   8106  C  C   . GLY C 2 25  ? 156.383 147.191 120.369 1.00 62.12  ? 25  GLY C C   1 
ATOM   8107  O  O   . GLY C 2 25  ? 157.611 147.128 120.279 1.00 62.12  ? 25  GLY C O   1 
ATOM   8108  N  N   . GLN C 2 26  ? 155.713 148.336 120.301 1.00 66.48  ? 26  GLN C N   1 
ATOM   8109  C  CA  . GLN C 2 26  ? 156.424 149.598 120.181 1.00 66.48  ? 26  GLN C CA  1 
ATOM   8110  C  C   . GLN C 2 26  ? 156.738 150.158 121.561 1.00 66.48  ? 26  GLN C C   1 
ATOM   8111  O  O   . GLN C 2 26  ? 155.839 150.412 122.367 1.00 66.48  ? 26  GLN C O   1 
ATOM   8112  C  CB  . GLN C 2 26  ? 155.601 150.602 119.379 1.00 66.48  ? 26  GLN C CB  1 
ATOM   8113  C  CG  . GLN C 2 26  ? 156.333 151.899 119.094 1.00 66.48  ? 26  GLN C CG  1 
ATOM   8114  C  CD  . GLN C 2 26  ? 155.509 152.863 118.271 1.00 66.48  ? 26  GLN C CD  1 
ATOM   8115  O  OE1 . GLN C 2 26  ? 154.355 152.590 117.945 1.00 66.48  ? 26  GLN C OE1 1 
ATOM   8116  N  NE2 . GLN C 2 26  ? 156.100 153.999 117.928 1.00 66.48  ? 26  GLN C NE2 1 
ATOM   8117  N  N   . GLY C 2 27  ? 158.027 150.347 121.832 1.00 64.34  ? 27  GLY C N   1 
ATOM   8118  C  CA  . GLY C 2 27  ? 158.475 150.811 123.126 1.00 64.34  ? 27  GLY C CA  1 
ATOM   8119  C  C   . GLY C 2 27  ? 158.572 149.743 124.191 1.00 64.34  ? 27  GLY C C   1 
ATOM   8120  O  O   . GLY C 2 27  ? 158.338 150.044 125.368 1.00 64.34  ? 27  GLY C O   1 
ATOM   8121  N  N   . HIS C 2 28  ? 158.909 148.510 123.822 1.00 57.71  ? 28  HIS C N   1 
ATOM   8122  C  CA  . HIS C 2 28  ? 159.007 147.426 124.786 1.00 57.71  ? 28  HIS C CA  1 
ATOM   8123  C  C   . HIS C 2 28  ? 160.477 147.075 125.010 1.00 57.71  ? 28  HIS C C   1 
ATOM   8124  O  O   . HIS C 2 28  ? 161.258 147.055 124.057 1.00 57.71  ? 28  HIS C O   1 
ATOM   8125  C  CB  . HIS C 2 28  ? 158.251 146.201 124.285 1.00 57.71  ? 28  HIS C CB  1 
ATOM   8126  C  CG  . HIS C 2 28  ? 158.020 145.162 125.335 1.00 57.71  ? 28  HIS C CG  1 
ATOM   8127  N  ND1 . HIS C 2 28  ? 156.989 145.245 126.244 1.00 57.71  ? 28  HIS C ND1 1 
ATOM   8128  C  CD2 . HIS C 2 28  ? 158.704 144.036 125.643 1.00 57.71  ? 28  HIS C CD2 1 
ATOM   8129  C  CE1 . HIS C 2 28  ? 157.032 144.201 127.052 1.00 57.71  ? 28  HIS C CE1 1 
ATOM   8130  N  NE2 . HIS C 2 28  ? 158.065 143.453 126.710 1.00 57.71  ? 28  HIS C NE2 1 
ATOM   8131  N  N   . PRO C 2 29  ? 160.885 146.800 126.252 1.00 55.52  ? 29  PRO C N   1 
ATOM   8132  C  CA  . PRO C 2 29  ? 162.320 146.619 126.519 1.00 55.52  ? 29  PRO C CA  1 
ATOM   8133  C  C   . PRO C 2 29  ? 162.952 145.434 125.808 1.00 55.52  ? 29  PRO C C   1 
ATOM   8134  O  O   . PRO C 2 29  ? 164.106 145.543 125.376 1.00 55.52  ? 29  PRO C O   1 
ATOM   8135  C  CB  . PRO C 2 29  ? 162.370 146.445 128.041 1.00 55.52  ? 29  PRO C CB  1 
ATOM   8136  C  CG  . PRO C 2 29  ? 161.152 147.123 128.532 1.00 55.52  ? 29  PRO C CG  1 
ATOM   8137  C  CD  . PRO C 2 29  ? 160.103 146.872 127.496 1.00 55.52  ? 29  PRO C CD  1 
ATOM   8138  N  N   . MET C 2 30  ? 162.257 144.308 125.675 1.00 56.30  ? 30  MET C N   1 
ATOM   8139  C  CA  . MET C 2 30  ? 162.868 143.099 125.134 1.00 56.30  ? 30  MET C CA  1 
ATOM   8140  C  C   . MET C 2 30  ? 162.696 143.051 123.621 1.00 56.30  ? 30  MET C C   1 
ATOM   8141  O  O   . MET C 2 30  ? 161.568 143.041 123.117 1.00 56.30  ? 30  MET C O   1 
ATOM   8142  C  CB  . MET C 2 30  ? 162.279 141.847 125.777 1.00 56.30  ? 30  MET C CB  1 
ATOM   8143  C  CG  . MET C 2 30  ? 162.975 140.573 125.326 1.00 56.30  ? 30  MET C CG  1 
ATOM   8144  S  SD  . MET C 2 30  ? 162.373 139.088 126.139 1.00 56.30  ? 30  MET C SD  1 
ATOM   8145  C  CE  . MET C 2 30  ? 163.093 139.292 127.764 1.00 56.30  ? 30  MET C CE  1 
ATOM   8146  N  N   . LYS C 2 31  ? 163.813 143.014 122.905 1.00 56.18  ? 31  LYS C N   1 
ATOM   8147  C  CA  . LYS C 2 31  ? 163.822 142.899 121.448 1.00 56.18  ? 31  LYS C CA  1 
ATOM   8148  C  C   . LYS C 2 31  ? 164.575 141.637 121.060 1.00 56.18  ? 31  LYS C C   1 
ATOM   8149  O  O   . LYS C 2 31  ? 165.820 141.653 121.040 1.00 56.18  ? 31  LYS C O   1 
ATOM   8150  C  CB  . LYS C 2 31  ? 164.484 144.118 120.805 1.00 56.18  ? 31  LYS C CB  1 
ATOM   8151  C  CG  . LYS C 2 31  ? 163.837 145.454 121.117 1.00 56.18  ? 31  LYS C CG  1 
ATOM   8152  C  CD  . LYS C 2 31  ? 162.430 145.526 120.561 1.00 56.18  ? 31  LYS C CD  1 
ATOM   8153  C  CE  . LYS C 2 31  ? 161.886 146.942 120.614 1.00 56.18  ? 31  LYS C CE  1 
ATOM   8154  N  NZ  . LYS C 2 31  ? 161.660 147.432 121.992 1.00 56.18  ? 31  LYS C NZ  1 
ATOM   8155  N  N   . PRO C 2 32  ? 163.893 140.536 120.724 1.00 55.17  ? 32  PRO C N   1 
ATOM   8156  C  CA  . PRO C 2 32  ? 164.597 139.276 120.430 1.00 55.17  ? 32  PRO C CA  1 
ATOM   8157  C  C   . PRO C 2 32  ? 165.685 139.385 119.370 1.00 55.17  ? 32  PRO C C   1 
ATOM   8158  O  O   . PRO C 2 32  ? 166.541 138.491 119.297 1.00 55.17  ? 32  PRO C O   1 
ATOM   8159  C  CB  . PRO C 2 32  ? 163.464 138.353 119.960 1.00 55.17  ? 32  PRO C CB  1 
ATOM   8160  C  CG  . PRO C 2 32  ? 162.247 138.899 120.615 1.00 55.17  ? 32  PRO C CG  1 
ATOM   8161  C  CD  . PRO C 2 32  ? 162.432 140.386 120.627 1.00 55.17  ? 32  PRO C CD  1 
ATOM   8162  N  N   . HIS C 2 33  ? 165.694 140.453 118.570 1.00 55.64  ? 33  HIS C N   1 
ATOM   8163  C  CA  . HIS C 2 33  ? 166.717 140.639 117.549 1.00 55.64  ? 33  HIS C CA  1 
ATOM   8164  C  C   . HIS C 2 33  ? 168.129 140.473 118.090 1.00 55.64  ? 33  HIS C C   1 
ATOM   8165  O  O   . HIS C 2 33  ? 169.014 140.063 117.332 1.00 55.64  ? 33  HIS C O   1 
ATOM   8166  C  CB  . HIS C 2 33  ? 166.576 142.019 116.908 1.00 55.64  ? 33  HIS C CB  1 
ATOM   8167  C  CG  . HIS C 2 33  ? 167.592 142.302 115.846 1.00 55.64  ? 33  HIS C CG  1 
ATOM   8168  N  ND1 . HIS C 2 33  ? 167.530 141.746 114.587 1.00 55.64  ? 33  HIS C ND1 1 
ATOM   8169  C  CD2 . HIS C 2 33  ? 168.699 143.080 115.858 1.00 55.64  ? 33  HIS C CD2 1 
ATOM   8170  C  CE1 . HIS C 2 33  ? 168.553 142.171 113.868 1.00 55.64  ? 33  HIS C CE1 1 
ATOM   8171  N  NE2 . HIS C 2 33  ? 169.278 142.982 114.617 1.00 55.64  ? 33  HIS C NE2 1 
ATOM   8172  N  N   . ARG C 2 34  ? 168.357 140.764 119.378 1.00 52.68  ? 34  ARG C N   1 
ATOM   8173  C  CA  . ARG C 2 34  ? 169.706 140.656 119.927 1.00 52.68  ? 34  ARG C CA  1 
ATOM   8174  C  C   . ARG C 2 34  ? 170.292 139.282 119.652 1.00 52.68  ? 34  ARG C C   1 
ATOM   8175  O  O   . ARG C 2 34  ? 171.474 139.164 119.300 1.00 52.68  ? 34  ARG C O   1 
ATOM   8176  C  CB  . ARG C 2 34  ? 169.717 140.958 121.430 1.00 52.68  ? 34  ARG C CB  1 
ATOM   8177  C  CG  . ARG C 2 34  ? 169.229 139.849 122.354 1.00 52.68  ? 34  ARG C CG  1 
ATOM   8178  C  CD  . ARG C 2 34  ? 167.757 139.966 122.673 1.00 52.68  ? 34  ARG C CD  1 
ATOM   8179  N  NE  . ARG C 2 34  ? 167.332 138.995 123.676 1.00 52.68  ? 34  ARG C NE  1 
ATOM   8180  C  CZ  . ARG C 2 34  ? 167.183 139.274 124.966 1.00 52.68  ? 34  ARG C CZ  1 
ATOM   8181  N  NH1 . ARG C 2 34  ? 167.420 140.498 125.411 1.00 52.68  ? 34  ARG C NH1 1 
ATOM   8182  N  NH2 . ARG C 2 34  ? 166.793 138.330 125.808 1.00 52.68  ? 34  ARG C NH2 1 
ATOM   8183  N  N   . ILE C 2 35  ? 169.461 138.237 119.745 1.00 53.48  ? 35  ILE C N   1 
ATOM   8184  C  CA  . ILE C 2 35  ? 169.928 136.885 119.458 1.00 53.48  ? 35  ILE C CA  1 
ATOM   8185  C  C   . ILE C 2 35  ? 170.621 136.845 118.106 1.00 53.48  ? 35  ILE C C   1 
ATOM   8186  O  O   . ILE C 2 35  ? 171.796 136.465 118.006 1.00 53.48  ? 35  ILE C O   1 
ATOM   8187  C  CB  . ILE C 2 35  ? 168.756 135.891 119.525 1.00 53.48  ? 35  ILE C CB  1 
ATOM   8188  C  CG1 . ILE C 2 35  ? 168.150 135.885 120.926 1.00 53.48  ? 35  ILE C CG1 1 
ATOM   8189  C  CG2 . ILE C 2 35  ? 169.227 134.503 119.152 1.00 53.48  ? 35  ILE C CG2 1 
ATOM   8190  C  CD1 . ILE C 2 35  ? 166.834 135.167 121.012 1.00 53.48  ? 35  ILE C CD1 1 
ATOM   8191  N  N   . ARG C 2 36  ? 169.926 137.292 117.054 1.00 57.22  ? 36  ARG C N   1 
ATOM   8192  C  CA  . ARG C 2 36  ? 170.528 137.300 115.726 1.00 57.22  ? 36  ARG C CA  1 
ATOM   8193  C  C   . ARG C 2 36  ? 171.858 138.036 115.727 1.00 57.22  ? 36  ARG C C   1 
ATOM   8194  O  O   . ARG C 2 36  ? 172.855 137.515 115.209 1.00 57.22  ? 36  ARG C O   1 
ATOM   8195  C  CB  . ARG C 2 36  ? 169.575 137.920 114.709 1.00 57.22  ? 36  ARG C CB  1 
ATOM   8196  C  CG  . ARG C 2 36  ? 168.342 137.084 114.440 1.00 57.22  ? 36  ARG C CG  1 
ATOM   8197  C  CD  . ARG C 2 36  ? 167.447 137.746 113.411 1.00 57.22  ? 36  ARG C CD  1 
ATOM   8198  N  NE  . ARG C 2 36  ? 168.055 137.774 112.086 1.00 57.22  ? 36  ARG C NE  1 
ATOM   8199  C  CZ  . ARG C 2 36  ? 167.557 138.450 111.057 1.00 57.22  ? 36  ARG C CZ  1 
ATOM   8200  N  NH1 . ARG C 2 36  ? 166.447 139.158 111.207 1.00 57.22  ? 36  ARG C NH1 1 
ATOM   8201  N  NH2 . ARG C 2 36  ? 168.169 138.422 109.882 1.00 57.22  ? 36  ARG C NH2 1 
ATOM   8202  N  N   . MET C 2 37  ? 171.910 139.224 116.341 1.00 57.56  ? 37  MET C N   1 
ATOM   8203  C  CA  . MET C 2 37  ? 173.176 139.944 116.384 1.00 57.56  ? 37  MET C CA  1 
ATOM   8204  C  C   . MET C 2 37  ? 174.266 139.090 117.007 1.00 57.56  ? 37  MET C C   1 
ATOM   8205  O  O   . MET C 2 37  ? 175.345 138.944 116.416 1.00 57.56  ? 37  MET C O   1 
ATOM   8206  C  CB  . MET C 2 37  ? 173.028 141.263 117.138 1.00 57.56  ? 37  MET C CB  1 
ATOM   8207  C  CG  . MET C 2 37  ? 172.220 142.302 116.388 1.00 57.56  ? 37  MET C CG  1 
ATOM   8208  S  SD  . MET C 2 37  ? 172.101 143.868 117.257 1.00 57.56  ? 37  MET C SD  1 
ATOM   8209  C  CE  . MET C 2 37  ? 173.791 144.441 117.150 1.00 57.56  ? 37  MET C CE  1 
ATOM   8210  N  N   . THR C 2 38  ? 173.982 138.475 118.160 1.00 53.89  ? 38  THR C N   1 
ATOM   8211  C  CA  . THR C 2 38  ? 174.939 137.550 118.752 1.00 53.89  ? 38  THR C CA  1 
ATOM   8212  C  C   . THR C 2 38  ? 175.383 136.519 117.729 1.00 53.89  ? 38  THR C C   1 
ATOM   8213  O  O   . THR C 2 38  ? 176.584 136.373 117.464 1.00 53.89  ? 38  THR C O   1 
ATOM   8214  C  CB  . THR C 2 38  ? 174.329 136.859 119.969 1.00 53.89  ? 38  THR C CB  1 
ATOM   8215  O  OG1 . THR C 2 38  ? 173.940 137.841 120.936 1.00 53.89  ? 38  THR C OG1 1 
ATOM   8216  C  CG2 . THR C 2 38  ? 175.338 135.920 120.594 1.00 53.89  ? 38  THR C CG2 1 
ATOM   8217  N  N   . HIS C 2 39  ? 174.416 135.846 117.096 1.00 57.77  ? 39  HIS C N   1 
ATOM   8218  C  CA  . HIS C 2 39  ? 174.733 134.852 116.080 1.00 57.77  ? 39  HIS C CA  1 
ATOM   8219  C  C   . HIS C 2 39  ? 175.708 135.409 115.058 1.00 57.77  ? 39  HIS C C   1 
ATOM   8220  O  O   . HIS C 2 39  ? 176.732 134.782 114.760 1.00 57.77  ? 39  HIS C O   1 
ATOM   8221  C  CB  . HIS C 2 39  ? 173.453 134.380 115.395 1.00 57.77  ? 39  HIS C CB  1 
ATOM   8222  C  CG  . HIS C 2 39  ? 173.678 133.354 114.330 1.00 57.77  ? 39  HIS C CG  1 
ATOM   8223  N  ND1 . HIS C 2 39  ? 174.009 132.047 114.613 1.00 57.77  ? 39  HIS C ND1 1 
ATOM   8224  C  CD2 . HIS C 2 39  ? 173.611 133.441 112.980 1.00 57.77  ? 39  HIS C CD2 1 
ATOM   8225  C  CE1 . HIS C 2 39  ? 174.141 131.374 113.484 1.00 57.77  ? 39  HIS C CE1 1 
ATOM   8226  N  NE2 . HIS C 2 39  ? 173.905 132.197 112.479 1.00 57.77  ? 39  HIS C NE2 1 
ATOM   8227  N  N   . ASN C 2 40  ? 175.441 136.617 114.558 1.00 61.10  ? 40  ASN C N   1 
ATOM   8228  C  CA  . ASN C 2 40  ? 176.260 137.138 113.474 1.00 61.10  ? 40  ASN C CA  1 
ATOM   8229  C  C   . ASN C 2 40  ? 177.695 137.353 113.933 1.00 61.10  ? 40  ASN C C   1 
ATOM   8230  O  O   . ASN C 2 40  ? 178.636 137.100 113.173 1.00 61.10  ? 40  ASN C O   1 
ATOM   8231  C  CB  . ASN C 2 40  ? 175.660 138.430 112.930 1.00 61.10  ? 40  ASN C CB  1 
ATOM   8232  C  CG  . ASN C 2 40  ? 176.239 138.816 111.588 1.00 61.10  ? 40  ASN C CG  1 
ATOM   8233  O  OD1 . ASN C 2 40  ? 177.116 138.136 111.059 1.00 61.10  ? 40  ASN C OD1 1 
ATOM   8234  N  ND2 . ASN C 2 40  ? 175.742 139.906 111.023 1.00 61.10  ? 40  ASN C ND2 1 
ATOM   8235  N  N   . LEU C 2 41  ? 177.888 137.784 115.182 1.00 58.61  ? 41  LEU C N   1 
ATOM   8236  C  CA  . LEU C 2 41  ? 179.249 137.908 115.689 1.00 58.61  ? 41  LEU C CA  1 
ATOM   8237  C  C   . LEU C 2 41  ? 179.926 136.548 115.744 1.00 58.61  ? 41  LEU C C   1 
ATOM   8238  O  O   . LEU C 2 41  ? 181.086 136.405 115.337 1.00 58.61  ? 41  LEU C O   1 
ATOM   8239  C  CB  . LEU C 2 41  ? 179.254 138.574 117.062 1.00 58.61  ? 41  LEU C CB  1 
ATOM   8240  C  CG  . LEU C 2 41  ? 178.905 140.060 117.063 1.00 58.61  ? 41  LEU C CG  1 
ATOM   8241  C  CD1 . LEU C 2 41  ? 178.824 140.587 118.482 1.00 58.61  ? 41  LEU C CD1 1 
ATOM   8242  C  CD2 . LEU C 2 41  ? 179.928 140.839 116.258 1.00 58.61  ? 41  LEU C CD2 1 
ATOM   8243  N  N   . LEU C 2 42  ? 179.201 135.525 116.202 1.00 59.66  ? 42  LEU C N   1 
ATOM   8244  C  CA  . LEU C 2 42  ? 179.761 134.179 116.208 1.00 59.66  ? 42  LEU C CA  1 
ATOM   8245  C  C   . LEU C 2 42  ? 180.029 133.697 114.791 1.00 59.66  ? 42  LEU C C   1 
ATOM   8246  O  O   . LEU C 2 42  ? 180.778 132.737 114.584 1.00 59.66  ? 42  LEU C O   1 
ATOM   8247  C  CB  . LEU C 2 42  ? 178.817 133.222 116.933 1.00 59.66  ? 42  LEU C CB  1 
ATOM   8248  C  CG  . LEU C 2 42  ? 178.662 133.476 118.429 1.00 59.66  ? 42  LEU C CG  1 
ATOM   8249  C  CD1 . LEU C 2 42  ? 177.580 132.594 119.016 1.00 59.66  ? 42  LEU C CD1 1 
ATOM   8250  C  CD2 . LEU C 2 42  ? 179.983 133.243 119.131 1.00 59.66  ? 42  LEU C CD2 1 
ATOM   8251  N  N   . LEU C 2 43  ? 179.435 134.361 113.800 1.00 64.21  ? 43  LEU C N   1 
ATOM   8252  C  CA  . LEU C 2 43  ? 179.620 133.941 112.419 1.00 64.21  ? 43  LEU C CA  1 
ATOM   8253  C  C   . LEU C 2 43  ? 180.803 134.668 111.788 1.00 64.21  ? 43  LEU C C   1 
ATOM   8254  O  O   . LEU C 2 43  ? 181.144 134.433 110.624 1.00 64.21  ? 43  LEU C O   1 
ATOM   8255  C  CB  . LEU C 2 43  ? 178.332 134.188 111.632 1.00 64.21  ? 43  LEU C CB  1 
ATOM   8256  C  CG  . LEU C 2 43  ? 178.195 133.617 110.222 1.00 64.21  ? 43  LEU C CG  1 
ATOM   8257  C  CD1 . LEU C 2 43  ? 178.197 132.102 110.268 1.00 64.21  ? 43  LEU C CD1 1 
ATOM   8258  C  CD2 . LEU C 2 43  ? 176.935 134.135 109.555 1.00 64.21  ? 43  LEU C CD2 1 
ATOM   8259  N  N   . ASN C 2 44  ? 181.452 135.552 112.547 1.00 64.60  ? 44  ASN C N   1 
ATOM   8260  C  CA  . ASN C 2 44  ? 182.578 136.298 111.999 1.00 64.60  ? 44  ASN C CA  1 
ATOM   8261  C  C   . ASN C 2 44  ? 183.844 136.184 112.838 1.00 64.60  ? 44  ASN C C   1 
ATOM   8262  O  O   . ASN C 2 44  ? 184.943 136.243 112.275 1.00 64.60  ? 44  ASN C O   1 
ATOM   8263  C  CB  . ASN C 2 44  ? 182.198 137.768 111.824 1.00 64.60  ? 44  ASN C CB  1 
ATOM   8264  C  CG  . ASN C 2 44  ? 181.140 137.968 110.762 1.00 64.60  ? 44  ASN C CG  1 
ATOM   8265  O  OD1 . ASN C 2 44  ? 180.022 138.386 111.052 1.00 64.60  ? 44  ASN C OD1 1 
ATOM   8266  N  ND2 . ASN C 2 44  ? 181.489 137.667 109.519 1.00 64.60  ? 44  ASN C ND2 1 
ATOM   8267  N  N   . TYR C 2 45  ? 183.726 136.029 114.156 1.00 66.62  ? 45  TYR C N   1 
ATOM   8268  C  CA  . TYR C 2 45  ? 184.880 135.712 114.987 1.00 66.62  ? 45  TYR C CA  1 
ATOM   8269  C  C   . TYR C 2 45  ? 185.556 134.408 114.595 1.00 66.62  ? 45  TYR C C   1 
ATOM   8270  O  O   . TYR C 2 45  ? 186.729 134.214 114.930 1.00 66.62  ? 45  TYR C O   1 
ATOM   8271  C  CB  . TYR C 2 45  ? 184.469 135.631 116.456 1.00 66.62  ? 45  TYR C CB  1 
ATOM   8272  C  CG  . TYR C 2 45  ? 184.348 136.958 117.160 1.00 66.62  ? 45  TYR C CG  1 
ATOM   8273  C  CD1 . TYR C 2 45  ? 185.006 138.084 116.687 1.00 66.62  ? 45  TYR C CD1 1 
ATOM   8274  C  CD2 . TYR C 2 45  ? 183.570 137.084 118.302 1.00 66.62  ? 45  TYR C CD2 1 
ATOM   8275  C  CE1 . TYR C 2 45  ? 184.901 139.291 117.340 1.00 66.62  ? 45  TYR C CE1 1 
ATOM   8276  C  CE2 . TYR C 2 45  ? 183.451 138.288 118.953 1.00 66.62  ? 45  TYR C CE2 1 
ATOM   8277  C  CZ  . TYR C 2 45  ? 184.119 139.387 118.467 1.00 66.62  ? 45  TYR C CZ  1 
ATOM   8278  O  OH  . TYR C 2 45  ? 184.008 140.591 119.114 1.00 66.62  ? 45  TYR C OH  1 
ATOM   8279  N  N   . GLY C 2 46  ? 184.855 133.521 113.895 1.00 66.35  ? 46  GLY C N   1 
ATOM   8280  C  CA  . GLY C 2 46  ? 185.380 132.202 113.624 1.00 66.35  ? 46  GLY C CA  1 
ATOM   8281  C  C   . GLY C 2 46  ? 185.028 131.185 114.677 1.00 66.35  ? 46  GLY C C   1 
ATOM   8282  O  O   . GLY C 2 46  ? 185.760 130.206 114.848 1.00 66.35  ? 46  GLY C O   1 
ATOM   8283  N  N   . LEU C 2 47  ? 183.931 131.396 115.402 1.00 62.79  ? 47  LEU C N   1 
ATOM   8284  C  CA  . LEU C 2 47  ? 183.533 130.507 116.483 1.00 62.79  ? 47  LEU C CA  1 
ATOM   8285  C  C   . LEU C 2 47  ? 182.408 129.565 116.090 1.00 62.79  ? 47  LEU C C   1 
ATOM   8286  O  O   . LEU C 2 47  ? 181.647 129.135 116.963 1.00 62.79  ? 47  LEU C O   1 
ATOM   8287  C  CB  . LEU C 2 47  ? 183.099 131.318 117.709 1.00 62.79  ? 47  LEU C CB  1 
ATOM   8288  C  CG  . LEU C 2 47  ? 184.176 132.169 118.382 1.00 62.79  ? 47  LEU C CG  1 
ATOM   8289  C  CD1 . LEU C 2 47  ? 183.595 132.974 119.522 1.00 62.79  ? 47  LEU C CD1 1 
ATOM   8290  C  CD2 . LEU C 2 47  ? 185.332 131.312 118.865 1.00 62.79  ? 47  LEU C CD2 1 
ATOM   8291  N  N   . TYR C 2 48  ? 182.268 129.251 114.809 1.00 68.89  ? 48  TYR C N   1 
ATOM   8292  C  CA  . TYR C 2 48  ? 181.276 128.286 114.367 1.00 68.89  ? 48  TYR C CA  1 
ATOM   8293  C  C   . TYR C 2 48  ? 181.886 127.181 113.516 1.00 68.89  ? 48  TYR C C   1 
ATOM   8294  O  O   . TYR C 2 48  ? 181.194 126.209 113.200 1.00 68.89  ? 48  TYR C O   1 
ATOM   8295  C  CB  . TYR C 2 48  ? 180.158 128.997 113.603 1.00 68.89  ? 48  TYR C CB  1 
ATOM   8296  C  CG  . TYR C 2 48  ? 180.592 129.569 112.275 1.00 68.89  ? 48  TYR C CG  1 
ATOM   8297  C  CD1 . TYR C 2 48  ? 181.213 130.816 112.193 1.00 68.89  ? 48  TYR C CD1 1 
ATOM   8298  C  CD2 . TYR C 2 48  ? 180.367 128.874 111.100 1.00 68.89  ? 48  TYR C CD2 1 
ATOM   8299  C  CE1 . TYR C 2 48  ? 181.610 131.340 110.974 1.00 68.89  ? 48  TYR C CE1 1 
ATOM   8300  C  CE2 . TYR C 2 48  ? 180.749 129.395 109.886 1.00 68.89  ? 48  TYR C CE2 1 
ATOM   8301  C  CZ  . TYR C 2 48  ? 181.367 130.620 109.826 1.00 68.89  ? 48  TYR C CZ  1 
ATOM   8302  O  OH  . TYR C 2 48  ? 181.743 131.112 108.604 1.00 68.89  ? 48  TYR C OH  1 
ATOM   8303  N  N   . ARG C 2 49  ? 183.163 127.305 113.141 1.00 73.54  ? 49  ARG C N   1 
ATOM   8304  C  CA  . ARG C 2 49  ? 183.879 126.163 112.584 1.00 73.54  ? 49  ARG C CA  1 
ATOM   8305  C  C   . ARG C 2 49  ? 183.983 125.035 113.598 1.00 73.54  ? 49  ARG C C   1 
ATOM   8306  O  O   . ARG C 2 49  ? 184.035 123.859 113.221 1.00 73.54  ? 49  ARG C O   1 
ATOM   8307  C  CB  . ARG C 2 49  ? 185.291 126.561 112.151 1.00 73.54  ? 49  ARG C CB  1 
ATOM   8308  C  CG  . ARG C 2 49  ? 185.433 127.341 110.856 1.00 73.54  ? 49  ARG C CG  1 
ATOM   8309  C  CD  . ARG C 2 49  ? 185.345 128.829 111.101 1.00 73.54  ? 49  ARG C CD  1 
ATOM   8310  N  NE  . ARG C 2 49  ? 185.989 129.575 110.026 1.00 73.54  ? 49  ARG C NE  1 
ATOM   8311  C  CZ  . ARG C 2 49  ? 185.367 130.013 108.940 1.00 73.54  ? 49  ARG C CZ  1 
ATOM   8312  N  NH1 . ARG C 2 49  ? 184.074 129.780 108.778 1.00 73.54  ? 49  ARG C NH1 1 
ATOM   8313  N  NH2 . ARG C 2 49  ? 186.041 130.682 108.015 1.00 73.54  ? 49  ARG C NH2 1 
ATOM   8314  N  N   . LYS C 2 50  ? 184.012 125.378 114.887 1.00 68.03  ? 50  LYS C N   1 
ATOM   8315  C  CA  . LYS C 2 50  ? 184.385 124.467 115.960 1.00 68.03  ? 50  LYS C CA  1 
ATOM   8316  C  C   . LYS C 2 50  ? 183.277 124.337 117.000 1.00 68.03  ? 50  LYS C C   1 
ATOM   8317  O  O   . LYS C 2 50  ? 183.544 124.325 118.204 1.00 68.03  ? 50  LYS C O   1 
ATOM   8318  C  CB  . LYS C 2 50  ? 185.690 124.931 116.607 1.00 68.03  ? 50  LYS C CB  1 
ATOM   8319  C  CG  . LYS C 2 50  ? 185.624 126.339 117.182 1.00 68.03  ? 50  LYS C CG  1 
ATOM   8320  C  CD  . LYS C 2 50  ? 186.959 126.768 117.760 1.00 68.03  ? 50  LYS C CD  1 
ATOM   8321  C  CE  . LYS C 2 50  ? 187.954 127.073 116.658 1.00 68.03  ? 50  LYS C CE  1 
ATOM   8322  N  NZ  . LYS C 2 50  ? 187.527 128.249 115.857 1.00 68.03  ? 50  LYS C NZ  1 
ATOM   8323  N  N   . MET C 2 51  ? 182.031 124.207 116.551 1.00 60.43  ? 51  MET C N   1 
ATOM   8324  C  CA  . MET C 2 51  ? 180.891 124.181 117.464 1.00 60.43  ? 51  MET C CA  1 
ATOM   8325  C  C   . MET C 2 51  ? 179.701 123.599 116.722 1.00 60.43  ? 51  MET C C   1 
ATOM   8326  O  O   . MET C 2 51  ? 179.257 124.177 115.726 1.00 60.43  ? 51  MET C O   1 
ATOM   8327  C  CB  . MET C 2 51  ? 180.593 125.589 117.979 1.00 60.43  ? 51  MET C CB  1 
ATOM   8328  C  CG  . MET C 2 51  ? 179.450 125.688 118.960 1.00 60.43  ? 51  MET C CG  1 
ATOM   8329  S  SD  . MET C 2 51  ? 179.309 127.360 119.611 1.00 60.43  ? 51  MET C SD  1 
ATOM   8330  C  CE  . MET C 2 51  ? 178.746 128.239 118.162 1.00 60.43  ? 51  MET C CE  1 
ATOM   8331  N  N   . GLU C 2 52  ? 179.193 122.461 117.191 1.00 61.49  ? 52  GLU C N   1 
ATOM   8332  C  CA  . GLU C 2 52  ? 178.130 121.777 116.466 1.00 61.49  ? 52  GLU C CA  1 
ATOM   8333  C  C   . GLU C 2 52  ? 176.838 122.582 116.509 1.00 61.49  ? 52  GLU C C   1 
ATOM   8334  O  O   . GLU C 2 52  ? 176.155 122.633 117.533 1.00 61.49  ? 52  GLU C O   1 
ATOM   8335  C  CB  . GLU C 2 52  ? 177.890 120.385 117.048 1.00 61.49  ? 52  GLU C CB  1 
ATOM   8336  C  CG  . GLU C 2 52  ? 179.020 119.404 116.825 1.00 61.49  ? 52  GLU C CG  1 
ATOM   8337  C  CD  . GLU C 2 52  ? 178.714 118.034 117.393 1.00 61.49  ? 52  GLU C CD  1 
ATOM   8338  O  OE1 . GLU C 2 52  ? 177.671 117.889 118.065 1.00 61.49  ? 52  GLU C OE1 1 
ATOM   8339  O  OE2 . GLU C 2 52  ? 179.511 117.100 117.168 1.00 61.49  ? 52  GLU C OE2 1 
ATOM   8340  N  N   . ILE C 2 53  ? 176.496 123.200 115.382 1.00 57.75  ? 53  ILE C N   1 
ATOM   8341  C  CA  . ILE C 2 53  ? 175.309 124.038 115.269 1.00 57.75  ? 53  ILE C CA  1 
ATOM   8342  C  C   . ILE C 2 53  ? 174.129 123.151 114.906 1.00 57.75  ? 53  ILE C C   1 
ATOM   8343  O  O   . ILE C 2 53  ? 174.210 122.361 113.959 1.00 57.75  ? 53  ILE C O   1 
ATOM   8344  C  CB  . ILE C 2 53  ? 175.496 125.152 114.223 1.00 57.75  ? 53  ILE C CB  1 
ATOM   8345  C  CG1 . ILE C 2 53  ? 176.638 126.080 114.630 1.00 57.75  ? 53  ILE C CG1 1 
ATOM   8346  C  CG2 . ILE C 2 53  ? 174.218 125.948 114.061 1.00 57.75  ? 53  ILE C CG2 1 
ATOM   8347  C  CD1 . ILE C 2 53  ? 177.049 127.048 113.543 1.00 57.75  ? 53  ILE C CD1 1 
ATOM   8348  N  N   . TYR C 2 54  ? 173.040 123.278 115.660 1.00 57.03  ? 54  TYR C N   1 
ATOM   8349  C  CA  . TYR C 2 54  ? 171.811 122.539 115.416 1.00 57.03  ? 54  TYR C CA  1 
ATOM   8350  C  C   . TYR C 2 54  ? 170.678 123.501 115.092 1.00 57.03  ? 54  TYR C C   1 
ATOM   8351  O  O   . TYR C 2 54  ? 170.881 124.712 114.975 1.00 57.03  ? 54  TYR C O   1 
ATOM   8352  C  CB  . TYR C 2 54  ? 171.400 121.692 116.624 1.00 57.03  ? 54  TYR C CB  1 
ATOM   8353  C  CG  . TYR C 2 54  ? 172.316 120.536 116.935 1.00 57.03  ? 54  TYR C CG  1 
ATOM   8354  C  CD1 . TYR C 2 54  ? 173.306 120.151 116.052 1.00 57.03  ? 54  TYR C CD1 1 
ATOM   8355  C  CD2 . TYR C 2 54  ? 172.171 119.812 118.103 1.00 57.03  ? 54  TYR C CD2 1 
ATOM   8356  C  CE1 . TYR C 2 54  ? 174.140 119.092 116.337 1.00 57.03  ? 54  TYR C CE1 1 
ATOM   8357  C  CE2 . TYR C 2 54  ? 172.995 118.750 118.388 1.00 57.03  ? 54  TYR C CE2 1 
ATOM   8358  C  CZ  . TYR C 2 54  ? 173.978 118.393 117.505 1.00 57.03  ? 54  TYR C CZ  1 
ATOM   8359  O  OH  . TYR C 2 54  ? 174.805 117.332 117.789 1.00 57.03  ? 54  TYR C OH  1 
ATOM   8360  N  N   . ARG C 2 55  ? 169.475 122.944 114.955 1.00 63.01  ? 55  ARG C N   1 
ATOM   8361  C  CA  . ARG C 2 55  ? 168.271 123.738 114.772 1.00 63.01  ? 55  ARG C CA  1 
ATOM   8362  C  C   . ARG C 2 55  ? 167.198 123.194 115.698 1.00 63.01  ? 55  ARG C C   1 
ATOM   8363  O  O   . ARG C 2 55  ? 166.863 122.006 115.603 1.00 63.01  ? 55  ARG C O   1 
ATOM   8364  C  CB  . ARG C 2 55  ? 167.798 123.686 113.322 1.00 63.01  ? 55  ARG C CB  1 
ATOM   8365  C  CG  . ARG C 2 55  ? 168.811 124.194 112.315 1.00 63.01  ? 55  ARG C CG  1 
ATOM   8366  C  CD  . ARG C 2 55  ? 169.042 125.688 112.451 1.00 63.01  ? 55  ARG C CD  1 
ATOM   8367  N  NE  . ARG C 2 55  ? 169.974 126.184 111.443 1.00 63.01  ? 55  ARG C NE  1 
ATOM   8368  C  CZ  . ARG C 2 55  ? 170.416 127.435 111.382 1.00 63.01  ? 55  ARG C CZ  1 
ATOM   8369  N  NH1 . ARG C 2 55  ? 170.014 128.328 112.275 1.00 63.01  ? 55  ARG C NH1 1 
ATOM   8370  N  NH2 . ARG C 2 55  ? 171.262 127.793 110.425 1.00 63.01  ? 55  ARG C NH2 1 
ATOM   8371  N  N   . PRO C 2 56  ? 166.632 123.998 116.592 1.00 59.54  ? 56  PRO C N   1 
ATOM   8372  C  CA  . PRO C 2 56  ? 165.663 123.461 117.551 1.00 59.54  ? 56  PRO C CA  1 
ATOM   8373  C  C   . PRO C 2 56  ? 164.396 122.968 116.874 1.00 59.54  ? 56  PRO C C   1 
ATOM   8374  O  O   . PRO C 2 56  ? 164.087 123.322 115.734 1.00 59.54  ? 56  PRO C O   1 
ATOM   8375  C  CB  . PRO C 2 56  ? 165.372 124.656 118.463 1.00 59.54  ? 56  PRO C CB  1 
ATOM   8376  C  CG  . PRO C 2 56  ? 165.664 125.839 117.629 1.00 59.54  ? 56  PRO C CG  1 
ATOM   8377  C  CD  . PRO C 2 56  ? 166.812 125.450 116.746 1.00 59.54  ? 56  PRO C CD  1 
ATOM   8378  N  N   . HIS C 2 57  ? 163.663 122.131 117.599 1.00 62.10  ? 57  HIS C N   1 
ATOM   8379  C  CA  . HIS C 2 57  ? 162.376 121.648 117.132 1.00 62.10  ? 57  HIS C CA  1 
ATOM   8380  C  C   . HIS C 2 57  ? 161.254 122.485 117.732 1.00 62.10  ? 57  HIS C C   1 
ATOM   8381  O  O   . HIS C 2 57  ? 161.327 122.929 118.881 1.00 62.10  ? 57  HIS C O   1 
ATOM   8382  C  CB  . HIS C 2 57  ? 162.184 120.177 117.502 1.00 62.10  ? 57  HIS C CB  1 
ATOM   8383  C  CG  . HIS C 2 57  ? 162.127 119.926 118.977 1.00 62.10  ? 57  HIS C CG  1 
ATOM   8384  N  ND1 . HIS C 2 57  ? 160.954 119.991 119.698 1.00 62.10  ? 57  HIS C ND1 1 
ATOM   8385  C  CD2 . HIS C 2 57  ? 163.097 119.611 119.866 1.00 62.10  ? 57  HIS C CD2 1 
ATOM   8386  C  CE1 . HIS C 2 57  ? 161.204 119.724 120.967 1.00 62.10  ? 57  HIS C CE1 1 
ATOM   8387  N  NE2 . HIS C 2 57  ? 162.497 119.490 121.096 1.00 62.10  ? 57  HIS C NE2 1 
ATOM   8388  N  N   . LYS C 2 58  ? 160.212 122.705 116.938 1.00 63.32  ? 58  LYS C N   1 
ATOM   8389  C  CA  . LYS C 2 58  ? 159.061 123.471 117.395 1.00 63.32  ? 58  LYS C CA  1 
ATOM   8390  C  C   . LYS C 2 58  ? 158.358 122.695 118.502 1.00 63.32  ? 58  LYS C C   1 
ATOM   8391  O  O   . LYS C 2 58  ? 157.662 121.710 118.232 1.00 63.32  ? 58  LYS C O   1 
ATOM   8392  C  CB  . LYS C 2 58  ? 158.114 123.749 116.230 1.00 63.32  ? 58  LYS C CB  1 
ATOM   8393  C  CG  . LYS C 2 58  ? 158.769 124.488 115.073 1.00 63.32  ? 58  LYS C CG  1 
ATOM   8394  C  CD  . LYS C 2 58  ? 159.293 125.846 115.503 1.00 63.32  ? 58  LYS C CD  1 
ATOM   8395  C  CE  . LYS C 2 58  ? 158.157 126.798 115.822 1.00 63.32  ? 58  LYS C CE  1 
ATOM   8396  N  NZ  . LYS C 2 58  ? 157.357 127.107 114.608 1.00 63.32  ? 58  LYS C NZ  1 
ATOM   8397  N  N   . ALA C 2 59  ? 158.545 123.135 119.745 1.00 64.31  ? 59  ALA C N   1 
ATOM   8398  C  CA  . ALA C 2 59  ? 158.043 122.393 120.893 1.00 64.31  ? 59  ALA C CA  1 
ATOM   8399  C  C   . ALA C 2 59  ? 156.521 122.320 120.882 1.00 64.31  ? 59  ALA C C   1 
ATOM   8400  O  O   . ALA C 2 59  ? 155.826 123.296 121.171 1.00 64.31  ? 59  ALA C O   1 
ATOM   8401  C  CB  . ALA C 2 59  ? 158.522 123.037 122.194 1.00 64.31  ? 59  ALA C CB  1 
ATOM   8402  N  N   . ASN C 2 60  ? 156.007 121.139 120.549 1.00 69.64  ? 60  ASN C N   1 
ATOM   8403  C  CA  . ASN C 2 60  ? 154.582 120.850 120.588 1.00 69.64  ? 60  ASN C CA  1 
ATOM   8404  C  C   . ASN C 2 60  ? 154.030 121.061 121.993 1.00 69.64  ? 60  ASN C C   1 
ATOM   8405  O  O   . ASN C 2 60  ? 154.754 120.959 122.986 1.00 69.64  ? 60  ASN C O   1 
ATOM   8406  C  CB  . ASN C 2 60  ? 154.310 119.420 120.110 1.00 69.64  ? 60  ASN C CB  1 
ATOM   8407  C  CG  . ASN C 2 60  ? 155.092 118.374 120.892 1.00 69.64  ? 60  ASN C CG  1 
ATOM   8408  O  OD1 . ASN C 2 60  ? 155.779 118.684 121.864 1.00 69.64  ? 60  ASN C OD1 1 
ATOM   8409  N  ND2 . ASN C 2 60  ? 154.992 117.122 120.460 1.00 69.64  ? 60  ASN C ND2 1 
ATOM   8410  N  N   . ALA C 2 61  ? 152.732 121.361 122.069 1.00 69.68  ? 61  ALA C N   1 
ATOM   8411  C  CA  . ALA C 2 61  ? 152.137 121.733 123.348 1.00 69.68  ? 61  ALA C CA  1 
ATOM   8412  C  C   . ALA C 2 61  ? 151.853 120.532 124.242 1.00 69.68  ? 61  ALA C C   1 
ATOM   8413  O  O   . ALA C 2 61  ? 151.072 120.657 125.191 1.00 69.68  ? 61  ALA C O   1 
ATOM   8414  C  CB  . ALA C 2 61  ? 150.846 122.519 123.117 1.00 69.68  ? 61  ALA C CB  1 
ATOM   8415  N  N   . GLU C 2 62  ? 152.460 119.375 123.968 1.00 72.13  ? 62  GLU C N   1 
ATOM   8416  C  CA  . GLU C 2 62  ? 152.252 118.219 124.835 1.00 72.13  ? 62  GLU C CA  1 
ATOM   8417  C  C   . GLU C 2 62  ? 153.431 118.013 125.776 1.00 72.13  ? 62  GLU C C   1 
ATOM   8418  O  O   . GLU C 2 62  ? 153.325 117.271 126.761 1.00 72.13  ? 62  GLU C O   1 
ATOM   8419  C  CB  . GLU C 2 62  ? 151.995 116.965 123.999 1.00 72.13  ? 62  GLU C CB  1 
ATOM   8420  C  CG  . GLU C 2 62  ? 150.617 116.920 123.348 1.00 72.13  ? 62  GLU C CG  1 
ATOM   8421  C  CD  . GLU C 2 62  ? 150.544 117.697 122.050 1.00 72.13  ? 62  GLU C CD  1 
ATOM   8422  O  OE1 . GLU C 2 62  ? 151.586 118.222 121.605 1.00 72.13  ? 62  GLU C OE1 1 
ATOM   8423  O  OE2 . GLU C 2 62  ? 149.441 117.785 121.473 1.00 72.13  ? 62  GLU C OE2 1 
ATOM   8424  N  N   . GLU C 2 63  ? 154.567 118.649 125.488 1.00 69.49  ? 63  GLU C N   1 
ATOM   8425  C  CA  . GLU C 2 63  ? 155.648 118.712 126.463 1.00 69.49  ? 63  GLU C CA  1 
ATOM   8426  C  C   . GLU C 2 63  ? 155.686 120.045 127.194 1.00 69.49  ? 63  GLU C C   1 
ATOM   8427  O  O   . GLU C 2 63  ? 156.324 120.138 128.246 1.00 69.49  ? 63  GLU C O   1 
ATOM   8428  C  CB  . GLU C 2 63  ? 157.002 118.459 125.799 1.00 69.49  ? 63  GLU C CB  1 
ATOM   8429  C  CG  . GLU C 2 63  ? 157.464 119.558 124.868 1.00 69.49  ? 63  GLU C CG  1 
ATOM   8430  C  CD  . GLU C 2 63  ? 158.792 119.232 124.216 1.00 69.49  ? 63  GLU C CD  1 
ATOM   8431  O  OE1 . GLU C 2 63  ? 159.331 118.138 124.483 1.00 69.49  ? 63  GLU C OE1 1 
ATOM   8432  O  OE2 . GLU C 2 63  ? 159.299 120.066 123.436 1.00 69.49  ? 63  GLU C OE2 1 
ATOM   8433  N  N   . MET C 2 64  ? 155.029 121.071 126.661 1.00 67.38  ? 64  MET C N   1 
ATOM   8434  C  CA  . MET C 2 64  ? 154.829 122.323 127.373 1.00 67.38  ? 64  MET C CA  1 
ATOM   8435  C  C   . MET C 2 64  ? 153.800 122.199 128.485 1.00 67.38  ? 64  MET C C   1 
ATOM   8436  O  O   . MET C 2 64  ? 153.588 123.164 129.226 1.00 67.38  ? 64  MET C O   1 
ATOM   8437  C  CB  . MET C 2 64  ? 154.394 123.416 126.392 1.00 67.38  ? 64  MET C CB  1 
ATOM   8438  C  CG  . MET C 2 64  ? 155.454 123.793 125.372 1.00 67.38  ? 64  MET C CG  1 
ATOM   8439  S  SD  . MET C 2 64  ? 154.833 124.928 124.122 1.00 67.38  ? 64  MET C SD  1 
ATOM   8440  C  CE  . MET C 2 64  ? 154.580 126.395 125.106 1.00 67.38  ? 64  MET C CE  1 
ATOM   8441  N  N   . THR C 2 65  ? 153.160 121.038 128.614 1.00 68.41  ? 65  THR C N   1 
ATOM   8442  C  CA  . THR C 2 65  ? 152.128 120.805 129.613 1.00 68.41  ? 65  THR C CA  1 
ATOM   8443  C  C   . THR C 2 65  ? 152.640 120.015 130.812 1.00 68.41  ? 65  THR C C   1 
ATOM   8444  O  O   . THR C 2 65  ? 152.034 120.087 131.887 1.00 68.41  ? 65  THR C O   1 
ATOM   8445  C  CB  . THR C 2 65  ? 150.942 120.074 128.966 1.00 68.41  ? 65  THR C CB  1 
ATOM   8446  O  OG1 . THR C 2 65  ? 150.497 120.816 127.825 1.00 68.41  ? 65  THR C OG1 1 
ATOM   8447  C  CG2 . THR C 2 65  ? 149.776 119.949 129.932 1.00 68.41  ? 65  THR C CG2 1 
ATOM   8448  N  N   . LYS C 2 66  ? 153.759 119.297 130.675 1.00 64.42  ? 66  LYS C N   1 
ATOM   8449  C  CA  . LYS C 2 66  ? 154.298 118.546 131.806 1.00 64.42  ? 66  LYS C CA  1 
ATOM   8450  C  C   . LYS C 2 66  ? 154.741 119.453 132.948 1.00 64.42  ? 66  LYS C C   1 
ATOM   8451  O  O   . LYS C 2 66  ? 155.198 118.951 133.980 1.00 64.42  ? 66  LYS C O   1 
ATOM   8452  C  CB  . LYS C 2 66  ? 155.460 117.660 131.354 1.00 64.42  ? 66  LYS C CB  1 
ATOM   8453  C  CG  . LYS C 2 66  ? 156.695 118.414 130.898 1.00 64.42  ? 66  LYS C CG  1 
ATOM   8454  C  CD  . LYS C 2 66  ? 157.769 117.455 130.405 1.00 64.42  ? 66  LYS C CD  1 
ATOM   8455  C  CE  . LYS C 2 66  ? 159.021 118.194 129.961 1.00 64.42  ? 66  LYS C CE  1 
ATOM   8456  N  NZ  . LYS C 2 66  ? 160.068 117.266 129.457 1.00 64.42  ? 66  LYS C NZ  1 
ATOM   8457  N  N   . TYR C 2 67  ? 154.628 120.769 132.782 1.00 62.25  ? 67  TYR C N   1 
ATOM   8458  C  CA  . TYR C 2 67  ? 154.775 121.728 133.869 1.00 62.25  ? 67  TYR C CA  1 
ATOM   8459  C  C   . TYR C 2 67  ? 153.622 122.715 133.933 1.00 62.25  ? 67  TYR C C   1 
ATOM   8460  O  O   . TYR C 2 67  ? 152.918 122.772 134.948 1.00 62.25  ? 67  TYR C O   1 
ATOM   8461  C  CB  . TYR C 2 67  ? 156.103 122.489 133.747 1.00 62.25  ? 67  TYR C CB  1 
ATOM   8462  C  CG  . TYR C 2 67  ? 156.221 123.619 134.741 1.00 62.25  ? 67  TYR C CG  1 
ATOM   8463  C  CD1 . TYR C 2 67  ? 156.378 123.368 136.093 1.00 62.25  ? 67  TYR C CD1 1 
ATOM   8464  C  CD2 . TYR C 2 67  ? 156.174 124.940 134.325 1.00 62.25  ? 67  TYR C CD2 1 
ATOM   8465  C  CE1 . TYR C 2 67  ? 156.479 124.400 137.002 1.00 62.25  ? 67  TYR C CE1 1 
ATOM   8466  C  CE2 . TYR C 2 67  ? 156.278 125.977 135.227 1.00 62.25  ? 67  TYR C CE2 1 
ATOM   8467  C  CZ  . TYR C 2 67  ? 156.430 125.702 136.563 1.00 62.25  ? 67  TYR C CZ  1 
ATOM   8468  O  OH  . TYR C 2 67  ? 156.535 126.733 137.467 1.00 62.25  ? 67  TYR C OH  1 
ATOM   8469  N  N   . HIS C 2 68  ? 153.403 123.497 132.881 1.00 66.63  ? 68  HIS C N   1 
ATOM   8470  C  CA  . HIS C 2 68  ? 152.345 124.493 132.910 1.00 66.63  ? 68  HIS C CA  1 
ATOM   8471  C  C   . HIS C 2 68  ? 150.976 123.826 132.872 1.00 66.63  ? 68  HIS C C   1 
ATOM   8472  O  O   . HIS C 2 68  ? 150.823 122.695 132.404 1.00 66.63  ? 68  HIS C O   1 
ATOM   8473  C  CB  . HIS C 2 68  ? 152.494 125.463 131.740 1.00 66.63  ? 68  HIS C CB  1 
ATOM   8474  C  CG  . HIS C 2 68  ? 153.736 126.295 131.805 1.00 66.63  ? 68  HIS C CG  1 
ATOM   8475  N  ND1 . HIS C 2 68  ? 153.865 127.378 132.647 1.00 66.63  ? 68  HIS C ND1 1 
ATOM   8476  C  CD2 . HIS C 2 68  ? 154.913 126.191 131.143 1.00 66.63  ? 68  HIS C CD2 1 
ATOM   8477  C  CE1 . HIS C 2 68  ? 155.065 127.909 132.496 1.00 66.63  ? 68  HIS C CE1 1 
ATOM   8478  N  NE2 . HIS C 2 68  ? 155.720 127.208 131.590 1.00 66.63  ? 68  HIS C NE2 1 
ATOM   8479  N  N   . SER C 2 69  ? 149.976 124.537 133.382 1.00 75.89  ? 69  SER C N   1 
ATOM   8480  C  CA  . SER C 2 69  ? 148.615 124.024 133.371 1.00 75.89  ? 69  SER C CA  1 
ATOM   8481  C  C   . SER C 2 69  ? 148.090 123.942 131.943 1.00 75.89  ? 69  SER C C   1 
ATOM   8482  O  O   . SER C 2 69  ? 148.703 124.448 131.001 1.00 75.89  ? 69  SER C O   1 
ATOM   8483  C  CB  . SER C 2 69  ? 147.703 124.904 134.223 1.00 75.89  ? 69  SER C CB  1 
ATOM   8484  O  OG  . SER C 2 69  ? 147.576 126.199 133.667 1.00 75.89  ? 69  SER C OG  1 
ATOM   8485  N  N   . ASP C 2 70  ? 146.935 123.296 131.788 1.00 79.56  ? 70  ASP C N   1 
ATOM   8486  C  CA  . ASP C 2 70  ? 146.426 123.026 130.447 1.00 79.56  ? 70  ASP C CA  1 
ATOM   8487  C  C   . ASP C 2 70  ? 145.686 124.231 129.879 1.00 79.56  ? 70  ASP C C   1 
ATOM   8488  O  O   . ASP C 2 70  ? 145.878 124.589 128.710 1.00 79.56  ? 70  ASP C O   1 
ATOM   8489  C  CB  . ASP C 2 70  ? 145.521 121.795 130.474 1.00 79.56  ? 70  ASP C CB  1 
ATOM   8490  C  CG  . ASP C 2 70  ? 145.229 121.252 129.087 1.00 79.56  ? 70  ASP C CG  1 
ATOM   8491  O  OD1 . ASP C 2 70  ? 145.719 121.837 128.098 1.00 79.56  ? 70  ASP C OD1 1 
ATOM   8492  O  OD2 . ASP C 2 70  ? 144.513 120.234 128.988 1.00 79.56  ? 70  ASP C OD2 1 
ATOM   8493  N  N   . ASP C 2 71  ? 144.838 124.871 130.687 1.00 79.76  ? 71  ASP C N   1 
ATOM   8494  C  CA  . ASP C 2 71  ? 144.080 126.019 130.196 1.00 79.76  ? 71  ASP C CA  1 
ATOM   8495  C  C   . ASP C 2 71  ? 144.998 127.185 129.847 1.00 79.76  ? 71  ASP C C   1 
ATOM   8496  O  O   . ASP C 2 71  ? 144.687 127.984 128.956 1.00 79.76  ? 71  ASP C O   1 
ATOM   8497  C  CB  . ASP C 2 71  ? 143.033 126.437 131.229 1.00 79.76  ? 71  ASP C CB  1 
ATOM   8498  C  CG  . ASP C 2 71  ? 143.640 126.789 132.575 1.00 79.76  ? 71  ASP C CG  1 
ATOM   8499  O  OD1 . ASP C 2 71  ? 144.870 126.646 132.741 1.00 79.76  ? 71  ASP C OD1 1 
ATOM   8500  O  OD2 . ASP C 2 71  ? 142.882 127.207 133.474 1.00 79.76  ? 71  ASP C OD2 1 
ATOM   8501  N  N   . TYR C 2 72  ? 146.135 127.298 130.537 1.00 74.79  ? 72  TYR C N   1 
ATOM   8502  C  CA  . TYR C 2 72  ? 147.109 128.333 130.203 1.00 74.79  ? 72  TYR C CA  1 
ATOM   8503  C  C   . TYR C 2 72  ? 147.698 128.110 128.817 1.00 74.79  ? 72  TYR C C   1 
ATOM   8504  O  O   . TYR C 2 72  ? 147.734 129.033 127.993 1.00 74.79  ? 72  TYR C O   1 
ATOM   8505  C  CB  . TYR C 2 72  ? 148.211 128.367 131.260 1.00 74.79  ? 72  TYR C CB  1 
ATOM   8506  C  CG  . TYR C 2 72  ? 149.335 129.334 130.971 1.00 74.79  ? 72  TYR C CG  1 
ATOM   8507  C  CD1 . TYR C 2 72  ? 149.150 130.702 131.086 1.00 74.79  ? 72  TYR C CD1 1 
ATOM   8508  C  CD2 . TYR C 2 72  ? 150.589 128.875 130.610 1.00 74.79  ? 72  TYR C CD2 1 
ATOM   8509  C  CE1 . TYR C 2 72  ? 150.178 131.585 130.832 1.00 74.79  ? 72  TYR C CE1 1 
ATOM   8510  C  CE2 . TYR C 2 72  ? 151.622 129.750 130.357 1.00 74.79  ? 72  TYR C CE2 1 
ATOM   8511  C  CZ  . TYR C 2 72  ? 151.411 131.104 130.467 1.00 74.79  ? 72  TYR C CZ  1 
ATOM   8512  O  OH  . TYR C 2 72  ? 152.440 131.979 130.213 1.00 74.79  ? 72  TYR C OH  1 
ATOM   8513  N  N   . ILE C 2 73  ? 148.159 126.890 128.538 1.00 75.21  ? 73  ILE C N   1 
ATOM   8514  C  CA  . ILE C 2 73  ? 148.741 126.599 127.232 1.00 75.21  ? 73  ILE C CA  1 
ATOM   8515  C  C   . ILE C 2 73  ? 147.689 126.727 126.139 1.00 75.21  ? 73  ILE C C   1 
ATOM   8516  O  O   . ILE C 2 73  ? 147.979 127.200 125.033 1.00 75.21  ? 73  ILE C O   1 
ATOM   8517  C  CB  . ILE C 2 73  ? 149.393 125.206 127.236 1.00 75.21  ? 73  ILE C CB  1 
ATOM   8518  C  CG1 . ILE C 2 73  ? 150.461 125.128 128.325 1.00 75.21  ? 73  ILE C CG1 1 
ATOM   8519  C  CG2 . ILE C 2 73  ? 149.998 124.903 125.881 1.00 75.21  ? 73  ILE C CG2 1 
ATOM   8520  C  CD1 . ILE C 2 73  ? 151.578 126.126 128.154 1.00 75.21  ? 73  ILE C CD1 1 
ATOM   8521  N  N   . LYS C 2 74  ? 146.452 126.313 126.426 1.00 80.51  ? 74  LYS C N   1 
ATOM   8522  C  CA  . LYS C 2 74  ? 145.377 126.502 125.457 1.00 80.51  ? 74  LYS C CA  1 
ATOM   8523  C  C   . LYS C 2 74  ? 145.120 127.982 125.207 1.00 80.51  ? 74  LYS C C   1 
ATOM   8524  O  O   . LYS C 2 74  ? 144.785 128.382 124.085 1.00 80.51  ? 74  LYS C O   1 
ATOM   8525  C  CB  . LYS C 2 74  ? 144.106 125.808 125.941 1.00 80.51  ? 74  LYS C CB  1 
ATOM   8526  C  CG  . LYS C 2 74  ? 144.188 124.293 125.922 1.00 80.51  ? 74  LYS C CG  1 
ATOM   8527  C  CD  . LYS C 2 74  ? 142.922 123.670 126.481 1.00 80.51  ? 74  LYS C CD  1 
ATOM   8528  C  CE  . LYS C 2 74  ? 141.749 123.877 125.538 1.00 80.51  ? 74  LYS C CE  1 
ATOM   8529  N  NZ  . LYS C 2 74  ? 141.924 123.119 124.269 1.00 80.51  ? 74  LYS C NZ  1 
ATOM   8530  N  N   . PHE C 2 75  ? 145.279 128.812 126.240 1.00 81.59  ? 75  PHE C N   1 
ATOM   8531  C  CA  . PHE C 2 75  ? 145.130 130.251 126.055 1.00 81.59  ? 75  PHE C CA  1 
ATOM   8532  C  C   . PHE C 2 75  ? 146.234 130.817 125.173 1.00 81.59  ? 75  PHE C C   1 
ATOM   8533  O  O   . PHE C 2 75  ? 145.958 131.572 124.234 1.00 81.59  ? 75  PHE C O   1 
ATOM   8534  C  CB  . PHE C 2 75  ? 145.112 130.965 127.404 1.00 81.59  ? 75  PHE C CB  1 
ATOM   8535  C  CG  . PHE C 2 75  ? 145.100 132.459 127.286 1.00 81.59  ? 75  PHE C CG  1 
ATOM   8536  C  CD1 . PHE C 2 75  ? 143.964 133.126 126.867 1.00 81.59  ? 75  PHE C CD1 1 
ATOM   8537  C  CD2 . PHE C 2 75  ? 146.232 133.197 127.585 1.00 81.59  ? 75  PHE C CD2 1 
ATOM   8538  C  CE1 . PHE C 2 75  ? 143.957 134.501 126.749 1.00 81.59  ? 75  PHE C CE1 1 
ATOM   8539  C  CE2 . PHE C 2 75  ? 146.230 134.571 127.471 1.00 81.59  ? 75  PHE C CE2 1 
ATOM   8540  C  CZ  . PHE C 2 75  ? 145.091 135.224 127.052 1.00 81.59  ? 75  PHE C CZ  1 
ATOM   8541  N  N   . LEU C 2 76  ? 147.494 130.475 125.464 1.00 76.30  ? 76  LEU C N   1 
ATOM   8542  C  CA  . LEU C 2 76  ? 148.590 130.981 124.643 1.00 76.30  ? 76  LEU C CA  1 
ATOM   8543  C  C   . LEU C 2 76  ? 148.460 130.511 123.202 1.00 76.30  ? 76  LEU C C   1 
ATOM   8544  O  O   . LEU C 2 76  ? 148.763 131.260 122.266 1.00 76.30  ? 76  LEU C O   1 
ATOM   8545  C  CB  . LEU C 2 76  ? 149.937 130.547 125.216 1.00 76.30  ? 76  LEU C CB  1 
ATOM   8546  C  CG  . LEU C 2 76  ? 150.359 131.134 126.560 1.00 76.30  ? 76  LEU C CG  1 
ATOM   8547  C  CD1 . LEU C 2 76  ? 151.683 130.534 126.984 1.00 76.30  ? 76  LEU C CD1 1 
ATOM   8548  C  CD2 . LEU C 2 76  ? 150.451 132.646 126.482 1.00 76.30  ? 76  LEU C CD2 1 
ATOM   8549  N  N   . ARG C 2 77  ? 148.006 129.274 123.004 1.00 78.96  ? 77  ARG C N   1 
ATOM   8550  C  CA  . ARG C 2 77  ? 147.861 128.756 121.649 1.00 78.96  ? 77  ARG C CA  1 
ATOM   8551  C  C   . ARG C 2 77  ? 146.645 129.363 120.961 1.00 78.96  ? 77  ARG C C   1 
ATOM   8552  O  O   . ARG C 2 77  ? 146.575 129.395 119.727 1.00 78.96  ? 77  ARG C O   1 
ATOM   8553  C  CB  . ARG C 2 77  ? 147.770 127.229 121.683 1.00 78.96  ? 77  ARG C CB  1 
ATOM   8554  C  CG  . ARG C 2 77  ? 147.820 126.565 120.319 1.00 78.96  ? 77  ARG C CG  1 
ATOM   8555  C  CD  . ARG C 2 77  ? 147.771 125.052 120.438 1.00 78.96  ? 77  ARG C CD  1 
ATOM   8556  N  NE  . ARG C 2 77  ? 146.482 124.582 120.938 1.00 78.96  ? 77  ARG C NE  1 
ATOM   8557  C  CZ  . ARG C 2 77  ? 146.233 123.326 121.293 1.00 78.96  ? 77  ARG C CZ  1 
ATOM   8558  N  NH1 . ARG C 2 77  ? 147.185 122.409 121.204 1.00 78.96  ? 77  ARG C NH1 1 
ATOM   8559  N  NH2 . ARG C 2 77  ? 145.031 122.986 121.738 1.00 78.96  ? 77  ARG C NH2 1 
ATOM   8560  N  N   . SER C 2 78  ? 145.687 129.869 121.740 1.00 85.84  ? 78  SER C N   1 
ATOM   8561  C  CA  . SER C 2 78  ? 144.482 130.461 121.172 1.00 85.84  ? 78  SER C CA  1 
ATOM   8562  C  C   . SER C 2 78  ? 144.339 131.948 121.477 1.00 85.84  ? 78  SER C C   1 
ATOM   8563  O  O   . SER C 2 78  ? 143.346 132.339 122.100 1.00 85.84  ? 78  SER C O   1 
ATOM   8564  C  CB  . SER C 2 78  ? 143.245 129.716 121.678 1.00 85.84  ? 78  SER C CB  1 
ATOM   8565  O  OG  . SER C 2 78  ? 143.245 128.370 121.233 1.00 85.84  ? 78  SER C OG  1 
ATOM   8566  N  N   . ILE C 2 79  ? 145.289 132.777 121.057 1.00 88.44  ? 79  ILE C N   1 
ATOM   8567  C  CA  . ILE C 2 79  ? 145.195 134.219 121.251 1.00 88.44  ? 79  ILE C CA  1 
ATOM   8568  C  C   . ILE C 2 79  ? 145.925 134.923 120.114 1.00 88.44  ? 79  ILE C C   1 
ATOM   8569  O  O   . ILE C 2 79  ? 146.878 134.392 119.534 1.00 88.44  ? 79  ILE C O   1 
ATOM   8570  C  CB  . ILE C 2 79  ? 145.753 134.622 122.632 1.00 88.44  ? 79  ILE C CB  1 
ATOM   8571  C  CG1 . ILE C 2 79  ? 145.377 136.065 122.970 1.00 88.44  ? 79  ILE C CG1 1 
ATOM   8572  C  CG2 . ILE C 2 79  ? 147.254 134.434 122.682 1.00 88.44  ? 79  ILE C CG2 1 
ATOM   8573  C  CD1 . ILE C 2 79  ? 143.898 136.276 123.158 1.00 88.44  ? 79  ILE C CD1 1 
ATOM   8574  N  N   . ARG C 2 80  ? 145.468 136.129 119.782 1.00 95.87  ? 80  ARG C N   1 
ATOM   8575  C  CA  . ARG C 2 80  ? 145.939 136.825 118.593 1.00 95.87  ? 80  ARG C CA  1 
ATOM   8576  C  C   . ARG C 2 80  ? 145.532 138.285 118.709 1.00 95.87  ? 80  ARG C C   1 
ATOM   8577  O  O   . ARG C 2 80  ? 144.434 138.575 119.197 1.00 95.87  ? 80  ARG C O   1 
ATOM   8578  C  CB  . ARG C 2 80  ? 145.345 136.182 117.330 1.00 95.87  ? 80  ARG C CB  1 
ATOM   8579  C  CG  . ARG C 2 80  ? 145.914 136.644 116.002 1.00 95.87  ? 80  ARG C CG  1 
ATOM   8580  C  CD  . ARG C 2 80  ? 145.315 135.828 114.869 1.00 95.87  ? 80  ARG C CD  1 
ATOM   8581  N  NE  . ARG C 2 80  ? 145.679 134.418 114.983 1.00 95.87  ? 80  ARG C NE  1 
ATOM   8582  C  CZ  . ARG C 2 80  ? 144.824 133.444 115.279 1.00 95.87  ? 80  ARG C CZ  1 
ATOM   8583  N  NH1 . ARG C 2 80  ? 143.546 133.724 115.496 1.00 95.87  ? 80  ARG C NH1 1 
ATOM   8584  N  NH2 . ARG C 2 80  ? 145.247 132.190 115.364 1.00 95.87  ? 80  ARG C NH2 1 
ATOM   8585  N  N   . PRO C 2 81  ? 146.386 139.225 118.289 1.00 94.03  ? 81  PRO C N   1 
ATOM   8586  C  CA  . PRO C 2 81  ? 146.061 140.646 118.495 1.00 94.03  ? 81  PRO C CA  1 
ATOM   8587  C  C   . PRO C 2 81  ? 144.862 141.137 117.701 1.00 94.03  ? 81  PRO C C   1 
ATOM   8588  O  O   . PRO C 2 81  ? 144.485 142.305 117.855 1.00 94.03  ? 81  PRO C O   1 
ATOM   8589  C  CB  . PRO C 2 81  ? 147.346 141.366 118.066 1.00 94.03  ? 81  PRO C CB  1 
ATOM   8590  C  CG  . PRO C 2 81  ? 148.006 140.427 117.133 1.00 94.03  ? 81  PRO C CG  1 
ATOM   8591  C  CD  . PRO C 2 81  ? 147.703 139.053 117.654 1.00 94.03  ? 81  PRO C CD  1 
ATOM   8592  N  N   . ASP C 2 82  ? 144.249 140.301 116.862 1.00 100.07 ? 82  ASP C N   1 
ATOM   8593  C  CA  . ASP C 2 82  ? 143.043 140.735 116.163 1.00 100.07 ? 82  ASP C CA  1 
ATOM   8594  C  C   . ASP C 2 82  ? 141.794 140.432 116.980 1.00 100.07 ? 82  ASP C C   1 
ATOM   8595  O  O   . ASP C 2 82  ? 140.838 141.217 116.979 1.00 100.07 ? 82  ASP C O   1 
ATOM   8596  C  CB  . ASP C 2 82  ? 142.966 140.080 114.783 1.00 100.07 ? 82  ASP C CB  1 
ATOM   8597  C  CG  . ASP C 2 82  ? 142.892 138.565 114.853 1.00 100.07 ? 82  ASP C CG  1 
ATOM   8598  O  OD1 . ASP C 2 82  ? 142.961 138.005 115.967 1.00 100.07 ? 82  ASP C OD1 1 
ATOM   8599  O  OD2 . ASP C 2 82  ? 142.762 137.930 113.785 1.00 100.07 ? 82  ASP C OD2 1 
ATOM   8600  N  N   . ASN C 2 83  ? 141.784 139.303 117.686 1.00 101.08 ? 83  ASN C N   1 
ATOM   8601  C  CA  . ASN C 2 83  ? 140.657 138.894 118.517 1.00 101.08 ? 83  ASN C CA  1 
ATOM   8602  C  C   . ASN C 2 83  ? 140.977 139.029 120.004 1.00 101.08 ? 83  ASN C C   1 
ATOM   8603  O  O   . ASN C 2 83  ? 140.655 138.152 120.808 1.00 101.08 ? 83  ASN C O   1 
ATOM   8604  C  CB  . ASN C 2 83  ? 140.223 137.469 118.178 1.00 101.08 ? 83  ASN C CB  1 
ATOM   8605  C  CG  . ASN C 2 83  ? 141.324 136.443 118.392 1.00 101.08 ? 83  ASN C CG  1 
ATOM   8606  O  OD1 . ASN C 2 83  ? 142.401 136.758 118.895 1.00 101.08 ? 83  ASN C OD1 1 
ATOM   8607  N  ND2 . ASN C 2 83  ? 141.053 135.202 118.009 1.00 101.08 ? 83  ASN C ND2 1 
ATOM   8608  N  N   . MET C 2 84  ? 141.621 140.136 120.382 1.00 101.78 ? 84  MET C N   1 
ATOM   8609  C  CA  . MET C 2 84  ? 141.854 140.410 121.795 1.00 101.78 ? 84  MET C CA  1 
ATOM   8610  C  C   . MET C 2 84  ? 140.556 140.643 122.552 1.00 101.78 ? 84  MET C C   1 
ATOM   8611  O  O   . MET C 2 84  ? 140.432 140.204 123.700 1.00 101.78 ? 84  MET C O   1 
ATOM   8612  C  CB  . MET C 2 84  ? 142.760 141.629 121.963 1.00 101.78 ? 84  MET C CB  1 
ATOM   8613  C  CG  . MET C 2 84  ? 144.178 141.442 121.471 1.00 101.78 ? 84  MET C CG  1 
ATOM   8614  S  SD  . MET C 2 84  ? 145.187 142.900 121.794 1.00 101.78 ? 84  MET C SD  1 
ATOM   8615  C  CE  . MET C 2 84  ? 144.543 144.039 120.573 1.00 101.78 ? 84  MET C CE  1 
ATOM   8616  N  N   . SER C 2 85  ? 139.591 141.325 121.936 1.00 104.06 ? 85  SER C N   1 
ATOM   8617  C  CA  . SER C 2 85  ? 138.317 141.641 122.564 1.00 104.06 ? 85  SER C CA  1 
ATOM   8618  C  C   . SER C 2 85  ? 137.526 140.398 122.953 1.00 104.06 ? 85  SER C C   1 
ATOM   8619  O  O   . SER C 2 85  ? 136.761 140.440 123.923 1.00 104.06 ? 85  SER C O   1 
ATOM   8620  C  CB  . SER C 2 85  ? 137.481 142.526 121.638 1.00 104.06 ? 85  SER C CB  1 
ATOM   8621  O  OG  . SER C 2 85  ? 137.115 141.827 120.461 1.00 104.06 ? 85  SER C OG  1 
ATOM   8622  N  N   . GLU C 2 86  ? 137.690 139.297 122.222 1.00 105.28 ? 86  GLU C N   1 
ATOM   8623  C  CA  . GLU C 2 86  ? 136.998 138.054 122.532 1.00 105.28 ? 86  GLU C CA  1 
ATOM   8624  C  C   . GLU C 2 86  ? 137.471 137.402 123.820 1.00 105.28 ? 86  GLU C C   1 
ATOM   8625  O  O   . GLU C 2 86  ? 136.638 136.961 124.614 1.00 105.28 ? 86  GLU C O   1 
ATOM   8626  C  CB  . GLU C 2 86  ? 137.154 137.055 121.377 1.00 105.28 ? 86  GLU C CB  1 
ATOM   8627  C  CG  . GLU C 2 86  ? 136.384 135.760 121.566 1.00 105.28 ? 86  GLU C CG  1 
ATOM   8628  C  CD  . GLU C 2 86  ? 136.492 134.839 120.367 1.00 105.28 ? 86  GLU C CD  1 
ATOM   8629  O  OE1 . GLU C 2 86  ? 137.182 135.206 119.393 1.00 105.28 ? 86  GLU C OE1 1 
ATOM   8630  O  OE2 . GLU C 2 86  ? 135.885 133.748 120.397 1.00 105.28 ? 86  GLU C OE2 1 
ATOM   8631  N  N   . TYR C 2 87  ? 138.779 137.334 124.049 1.00 99.88  ? 87  TYR C N   1 
ATOM   8632  C  CA  . TYR C 2 87  ? 139.350 136.838 125.294 1.00 99.88  ? 87  TYR C CA  1 
ATOM   8633  C  C   . TYR C 2 87  ? 139.644 137.992 126.245 1.00 99.88  ? 87  TYR C C   1 
ATOM   8634  O  O   . TYR C 2 87  ? 140.676 138.653 126.145 1.00 99.88  ? 87  TYR C O   1 
ATOM   8635  C  CB  . TYR C 2 87  ? 140.616 136.027 125.031 1.00 99.88  ? 87  TYR C CB  1 
ATOM   8636  C  CG  . TYR C 2 87  ? 140.379 134.720 124.310 1.00 99.88  ? 87  TYR C CG  1 
ATOM   8637  C  CD1 . TYR C 2 87  ? 139.959 133.592 124.999 1.00 99.88  ? 87  TYR C CD1 1 
ATOM   8638  C  CD2 . TYR C 2 87  ? 140.579 134.614 122.940 1.00 99.88  ? 87  TYR C CD2 1 
ATOM   8639  C  CE1 . TYR C 2 87  ? 139.743 132.394 124.346 1.00 99.88  ? 87  TYR C CE1 1 
ATOM   8640  C  CE2 . TYR C 2 87  ? 140.364 133.421 122.278 1.00 99.88  ? 87  TYR C CE2 1 
ATOM   8641  C  CZ  . TYR C 2 87  ? 139.947 132.315 122.985 1.00 99.88  ? 87  TYR C CZ  1 
ATOM   8642  O  OH  . TYR C 2 87  ? 139.732 131.126 122.330 1.00 99.88  ? 87  TYR C OH  1 
ATOM   8643  N  N   . SER C 2 88  ? 138.731 138.253 127.181 1.00 94.73  ? 88  SER C N   1 
ATOM   8644  C  CA  . SER C 2 88  ? 138.930 139.358 128.113 1.00 94.73  ? 88  SER C CA  1 
ATOM   8645  C  C   . SER C 2 88  ? 139.337 138.847 129.489 1.00 94.73  ? 88  SER C C   1 
ATOM   8646  O  O   . SER C 2 88  ? 140.467 139.072 129.943 1.00 94.73  ? 88  SER C O   1 
ATOM   8647  C  CB  . SER C 2 88  ? 137.658 140.202 128.199 1.00 94.73  ? 88  SER C CB  1 
ATOM   8648  O  OG  . SER C 2 88  ? 136.591 139.458 128.760 1.00 94.73  ? 88  SER C OG  1 
ATOM   8649  N  N   . LYS C 2 89  ? 138.422 138.152 130.170 1.00 91.33  ? 89  LYS C N   1 
ATOM   8650  C  CA  . LYS C 2 89  ? 138.737 137.604 131.484 1.00 91.33  ? 89  LYS C CA  1 
ATOM   8651  C  C   . LYS C 2 89  ? 139.880 136.601 131.403 1.00 91.33  ? 89  LYS C C   1 
ATOM   8652  O  O   . LYS C 2 89  ? 140.627 136.420 132.374 1.00 91.33  ? 89  LYS C O   1 
ATOM   8653  C  CB  . LYS C 2 89  ? 137.492 136.966 132.099 1.00 91.33  ? 89  LYS C CB  1 
ATOM   8654  C  CG  . LYS C 2 89  ? 136.984 135.742 131.362 1.00 91.33  ? 89  LYS C CG  1 
ATOM   8655  C  CD  . LYS C 2 89  ? 135.683 135.249 131.967 1.00 91.33  ? 89  LYS C CD  1 
ATOM   8656  C  CE  . LYS C 2 89  ? 135.914 134.639 133.338 1.00 91.33  ? 89  LYS C CE  1 
ATOM   8657  N  NZ  . LYS C 2 89  ? 134.662 134.077 133.914 1.00 91.33  ? 89  LYS C NZ  1 
ATOM   8658  N  N   . GLN C 2 90  ? 140.042 135.954 130.246 1.00 89.40  ? 90  GLN C N   1 
ATOM   8659  C  CA  . GLN C 2 90  ? 141.157 135.033 130.063 1.00 89.40  ? 90  GLN C CA  1 
ATOM   8660  C  C   . GLN C 2 90  ? 142.492 135.758 130.172 1.00 89.40  ? 90  GLN C C   1 
ATOM   8661  O  O   . GLN C 2 90  ? 143.368 135.344 130.939 1.00 89.40  ? 90  GLN C O   1 
ATOM   8662  C  CB  . GLN C 2 90  ? 141.036 134.323 128.715 1.00 89.40  ? 90  GLN C CB  1 
ATOM   8663  C  CG  . GLN C 2 90  ? 139.832 133.401 128.600 1.00 89.40  ? 90  GLN C CG  1 
ATOM   8664  C  CD  . GLN C 2 90  ? 139.885 132.244 129.575 1.00 89.40  ? 90  GLN C CD  1 
ATOM   8665  O  OE1 . GLN C 2 90  ? 139.125 132.194 130.541 1.00 89.40  ? 90  GLN C OE1 1 
ATOM   8666  N  NE2 . GLN C 2 90  ? 140.785 131.301 129.324 1.00 89.40  ? 90  GLN C NE2 1 
ATOM   8667  N  N   . MET C 2 91  ? 142.665 136.855 129.428 1.00 85.87  ? 91  MET C N   1 
ATOM   8668  C  CA  . MET C 2 91  ? 143.948 137.546 129.475 1.00 85.87  ? 91  MET C CA  1 
ATOM   8669  C  C   . MET C 2 91  ? 144.111 138.366 130.747 1.00 85.87  ? 91  MET C C   1 
ATOM   8670  O  O   . MET C 2 91  ? 145.244 138.640 131.155 1.00 85.87  ? 91  MET C O   1 
ATOM   8671  C  CB  . MET C 2 91  ? 144.149 138.435 128.246 1.00 85.87  ? 91  MET C CB  1 
ATOM   8672  C  CG  . MET C 2 91  ? 143.157 139.562 128.074 1.00 85.87  ? 91  MET C CG  1 
ATOM   8673  S  SD  . MET C 2 91  ? 143.663 140.643 126.721 1.00 85.87  ? 91  MET C SD  1 
ATOM   8674  C  CE  . MET C 2 91  ? 143.507 139.551 125.313 1.00 85.87  ? 91  MET C CE  1 
ATOM   8675  N  N   . GLN C 2 92  ? 143.015 138.769 131.394 1.00 89.21  ? 92  GLN C N   1 
ATOM   8676  C  CA  . GLN C 2 92  ? 143.192 139.419 132.687 1.00 89.21  ? 92  GLN C CA  1 
ATOM   8677  C  C   . GLN C 2 92  ? 143.459 138.414 133.796 1.00 89.21  ? 92  GLN C C   1 
ATOM   8678  O  O   . GLN C 2 92  ? 143.873 138.813 134.890 1.00 89.21  ? 92  GLN C O   1 
ATOM   8679  C  CB  . GLN C 2 92  ? 141.974 140.266 133.062 1.00 89.21  ? 92  GLN C CB  1 
ATOM   8680  C  CG  . GLN C 2 92  ? 140.778 139.465 133.526 1.00 89.21  ? 92  GLN C CG  1 
ATOM   8681  C  CD  . GLN C 2 92  ? 139.584 140.337 133.862 1.00 89.21  ? 92  GLN C CD  1 
ATOM   8682  O  OE1 . GLN C 2 92  ? 139.658 141.564 133.796 1.00 89.21  ? 92  GLN C OE1 1 
ATOM   8683  N  NE2 . GLN C 2 92  ? 138.474 139.704 134.227 1.00 89.21  ? 92  GLN C NE2 1 
ATOM   8684  N  N   . ARG C 2 93  ? 143.230 137.123 133.542 1.00 85.80  ? 93  ARG C N   1 
ATOM   8685  C  CA  . ARG C 2 93  ? 143.496 136.112 134.559 1.00 85.80  ? 93  ARG C CA  1 
ATOM   8686  C  C   . ARG C 2 93  ? 144.890 135.511 134.423 1.00 85.80  ? 93  ARG C C   1 
ATOM   8687  O  O   . ARG C 2 93  ? 145.472 135.082 135.426 1.00 85.80  ? 93  ARG C O   1 
ATOM   8688  C  CB  . ARG C 2 93  ? 142.425 135.019 134.503 1.00 85.80  ? 93  ARG C CB  1 
ATOM   8689  C  CG  . ARG C 2 93  ? 142.566 133.946 135.572 1.00 85.80  ? 93  ARG C CG  1 
ATOM   8690  C  CD  . ARG C 2 93  ? 141.350 133.031 135.619 1.00 85.80  ? 93  ARG C CD  1 
ATOM   8691  N  NE  . ARG C 2 93  ? 141.143 132.257 134.399 1.00 85.80  ? 93  ARG C NE  1 
ATOM   8692  C  CZ  . ARG C 2 93  ? 141.720 131.088 134.146 1.00 85.80  ? 93  ARG C CZ  1 
ATOM   8693  N  NH1 . ARG C 2 93  ? 142.548 130.547 135.029 1.00 85.80  ? 93  ARG C NH1 1 
ATOM   8694  N  NH2 . ARG C 2 93  ? 141.462 130.455 133.009 1.00 85.80  ? 93  ARG C NH2 1 
ATOM   8695  N  N   . PHE C 2 94  ? 145.451 135.486 133.215 1.00 79.15  ? 94  PHE C N   1 
ATOM   8696  C  CA  . PHE C 2 94  ? 146.786 134.947 132.993 1.00 79.15  ? 94  PHE C CA  1 
ATOM   8697  C  C   . PHE C 2 94  ? 147.854 136.027 132.866 1.00 79.15  ? 94  PHE C C   1 
ATOM   8698  O  O   . PHE C 2 94  ? 148.925 135.755 132.315 1.00 79.15  ? 94  PHE C O   1 
ATOM   8699  C  CB  . PHE C 2 94  ? 146.807 134.064 131.746 1.00 79.15  ? 94  PHE C CB  1 
ATOM   8700  C  CG  . PHE C 2 94  ? 145.986 132.817 131.869 1.00 79.15  ? 94  PHE C CG  1 
ATOM   8701  C  CD1 . PHE C 2 94  ? 146.419 131.764 132.651 1.00 79.15  ? 94  PHE C CD1 1 
ATOM   8702  C  CD2 . PHE C 2 94  ? 144.802 132.680 131.171 1.00 79.15  ? 94  PHE C CD2 1 
ATOM   8703  C  CE1 . PHE C 2 94  ? 145.671 130.611 132.757 1.00 79.15  ? 94  PHE C CE1 1 
ATOM   8704  C  CE2 . PHE C 2 94  ? 144.053 131.527 131.269 1.00 79.15  ? 94  PHE C CE2 1 
ATOM   8705  C  CZ  . PHE C 2 94  ? 144.489 130.492 132.063 1.00 79.15  ? 94  PHE C CZ  1 
ATOM   8706  N  N   . ASN C 2 95  ? 147.573 137.251 133.323 1.00 76.23  ? 95  ASN C N   1 
ATOM   8707  C  CA  . ASN C 2 95  ? 148.555 138.341 133.386 1.00 76.23  ? 95  ASN C CA  1 
ATOM   8708  C  C   . ASN C 2 95  ? 148.954 138.831 131.990 1.00 76.23  ? 95  ASN C C   1 
ATOM   8709  O  O   . ASN C 2 95  ? 149.478 139.933 131.818 1.00 76.23  ? 95  ASN C O   1 
ATOM   8710  C  CB  . ASN C 2 95  ? 149.786 137.922 134.198 1.00 76.23  ? 95  ASN C CB  1 
ATOM   8711  C  CG  . ASN C 2 95  ? 150.668 139.095 134.590 1.00 76.23  ? 95  ASN C CG  1 
ATOM   8712  O  OD1 . ASN C 2 95  ? 150.371 140.248 134.284 1.00 76.23  ? 95  ASN C OD1 1 
ATOM   8713  N  ND2 . ASN C 2 95  ? 151.764 138.800 135.276 1.00 76.23  ? 95  ASN C ND2 1 
ATOM   8714  N  N   . VAL C 2 96  ? 148.695 138.004 130.980 1.00 76.39  ? 96  VAL C N   1 
ATOM   8715  C  CA  . VAL C 2 96  ? 149.050 138.329 129.603 1.00 76.39  ? 96  VAL C CA  1 
ATOM   8716  C  C   . VAL C 2 96  ? 148.218 139.508 129.118 1.00 76.39  ? 96  VAL C C   1 
ATOM   8717  O  O   . VAL C 2 96  ? 146.984 139.451 129.124 1.00 76.39  ? 96  VAL C O   1 
ATOM   8718  C  CB  . VAL C 2 96  ? 148.859 137.112 128.682 1.00 76.39  ? 96  VAL C CB  1 
ATOM   8719  C  CG1 . VAL C 2 96  ? 149.120 137.495 127.241 1.00 76.39  ? 96  VAL C CG1 1 
ATOM   8720  C  CG2 . VAL C 2 96  ? 149.770 135.976 129.110 1.00 76.39  ? 96  VAL C CG2 1 
ATOM   8721  N  N   . GLY C 2 97  ? 148.880 140.581 128.695 1.00 73.54  ? 97  GLY C N   1 
ATOM   8722  C  CA  . GLY C 2 97  ? 148.163 141.726 128.171 1.00 73.54  ? 97  GLY C CA  1 
ATOM   8723  C  C   . GLY C 2 97  ? 148.847 143.063 128.374 1.00 73.54  ? 97  GLY C C   1 
ATOM   8724  O  O   . GLY C 2 97  ? 148.886 143.886 127.455 1.00 73.54  ? 97  GLY C O   1 
ATOM   8725  N  N   . GLU C 2 98  ? 149.390 143.299 129.570 1.00 75.29  ? 98  GLU C N   1 
ATOM   8726  C  CA  . GLU C 2 98  ? 149.963 144.608 129.864 1.00 75.29  ? 98  GLU C CA  1 
ATOM   8727  C  C   . GLU C 2 98  ? 151.483 144.570 129.977 1.00 75.29  ? 98  GLU C C   1 
ATOM   8728  O  O   . GLU C 2 98  ? 152.161 145.422 129.391 1.00 75.29  ? 98  GLU C O   1 
ATOM   8729  C  CB  . GLU C 2 98  ? 149.331 145.181 131.138 1.00 75.29  ? 98  GLU C CB  1 
ATOM   8730  C  CG  . GLU C 2 98  ? 149.619 144.415 132.423 1.00 75.29  ? 98  GLU C CG  1 
ATOM   8731  C  CD  . GLU C 2 98  ? 148.649 143.272 132.657 1.00 75.29  ? 98  GLU C CD  1 
ATOM   8732  O  OE1 . GLU C 2 98  ? 147.945 142.877 131.704 1.00 75.29  ? 98  GLU C OE1 1 
ATOM   8733  O  OE2 . GLU C 2 98  ? 148.587 142.769 133.798 1.00 75.29  ? 98  GLU C OE2 1 
ATOM   8734  N  N   . ASP C 2 99  ? 152.038 143.603 130.709 1.00 68.24  ? 99  ASP C N   1 
ATOM   8735  C  CA  . ASP C 2 99  ? 153.487 143.473 130.794 1.00 68.24  ? 99  ASP C CA  1 
ATOM   8736  C  C   . ASP C 2 99  ? 154.012 142.485 129.765 1.00 68.24  ? 99  ASP C C   1 
ATOM   8737  O  O   . ASP C 2 99  ? 155.067 142.717 129.166 1.00 68.24  ? 99  ASP C O   1 
ATOM   8738  C  CB  . ASP C 2 99  ? 153.897 143.028 132.198 1.00 68.24  ? 99  ASP C CB  1 
ATOM   8739  C  CG  . ASP C 2 99  ? 155.388 143.152 132.440 1.00 68.24  ? 99  ASP C CG  1 
ATOM   8740  O  OD1 . ASP C 2 99  ? 156.100 143.649 131.543 1.00 68.24  ? 99  ASP C OD1 1 
ATOM   8741  O  OD2 . ASP C 2 99  ? 155.852 142.732 133.520 1.00 68.24  ? 99  ASP C OD2 1 
ATOM   8742  N  N   . CYS C 2 100 ? 153.290 141.389 129.552 1.00 65.74  ? 100 CYS C N   1 
ATOM   8743  C  CA  . CYS C 2 100 ? 153.619 140.384 128.546 1.00 65.74  ? 100 CYS C CA  1 
ATOM   8744  C  C   . CYS C 2 100 ? 152.612 140.543 127.415 1.00 65.74  ? 100 CYS C C   1 
ATOM   8745  O  O   . CYS C 2 100 ? 151.550 139.908 127.420 1.00 65.74  ? 100 CYS C O   1 
ATOM   8746  C  CB  . CYS C 2 100 ? 153.587 138.980 129.146 1.00 65.74  ? 100 CYS C CB  1 
ATOM   8747  S  SG  . CYS C 2 100 ? 154.805 138.716 130.447 1.00 65.74  ? 100 CYS C SG  1 
ATOM   8748  N  N   . PRO C 2 101 ? 152.910 141.389 126.433 1.00 65.16  ? 101 PRO C N   1 
ATOM   8749  C  CA  . PRO C 2 101 ? 151.892 141.748 125.443 1.00 65.16  ? 101 PRO C CA  1 
ATOM   8750  C  C   . PRO C 2 101 ? 151.684 140.653 124.413 1.00 65.16  ? 101 PRO C C   1 
ATOM   8751  O  O   . PRO C 2 101 ? 152.607 139.919 124.053 1.00 65.16  ? 101 PRO C O   1 
ATOM   8752  C  CB  . PRO C 2 101 ? 152.467 143.008 124.792 1.00 65.16  ? 101 PRO C CB  1 
ATOM   8753  C  CG  . PRO C 2 101 ? 153.936 142.822 124.899 1.00 65.16  ? 101 PRO C CG  1 
ATOM   8754  C  CD  . PRO C 2 101 ? 154.177 142.101 126.201 1.00 65.16  ? 101 PRO C CD  1 
ATOM   8755  N  N   . VAL C 2 102 ? 150.448 140.555 123.936 1.00 69.94  ? 102 VAL C N   1 
ATOM   8756  C  CA  . VAL C 2 102 ? 150.131 139.674 122.821 1.00 69.94  ? 102 VAL C CA  1 
ATOM   8757  C  C   . VAL C 2 102 ? 150.663 140.293 121.537 1.00 69.94  ? 102 VAL C C   1 
ATOM   8758  O  O   . VAL C 2 102 ? 150.596 141.509 121.328 1.00 69.94  ? 102 VAL C O   1 
ATOM   8759  C  CB  . VAL C 2 102 ? 148.615 139.409 122.738 1.00 69.94  ? 102 VAL C CB  1 
ATOM   8760  C  CG1 . VAL C 2 102 ? 148.140 138.672 123.970 1.00 69.94  ? 102 VAL C CG1 1 
ATOM   8761  C  CG2 . VAL C 2 102 ? 147.857 140.707 122.588 1.00 69.94  ? 102 VAL C CG2 1 
ATOM   8762  N  N   . PHE C 2 103 ? 151.214 139.450 120.669 1.00 63.47  ? 103 PHE C N   1 
ATOM   8763  C  CA  . PHE C 2 103 ? 151.823 139.938 119.443 1.00 63.47  ? 103 PHE C CA  1 
ATOM   8764  C  C   . PHE C 2 103 ? 151.797 138.827 118.406 1.00 63.47  ? 103 PHE C C   1 
ATOM   8765  O  O   . PHE C 2 103 ? 151.625 137.649 118.733 1.00 63.47  ? 103 PHE C O   1 
ATOM   8766  C  CB  . PHE C 2 103 ? 153.252 140.439 119.691 1.00 63.47  ? 103 PHE C CB  1 
ATOM   8767  C  CG  . PHE C 2 103 ? 154.211 139.370 120.142 1.00 63.47  ? 103 PHE C CG  1 
ATOM   8768  C  CD1 . PHE C 2 103 ? 154.303 139.016 121.475 1.00 63.47  ? 103 PHE C CD1 1 
ATOM   8769  C  CD2 . PHE C 2 103 ? 155.052 138.748 119.237 1.00 63.47  ? 103 PHE C CD2 1 
ATOM   8770  C  CE1 . PHE C 2 103 ? 155.187 138.039 121.886 1.00 63.47  ? 103 PHE C CE1 1 
ATOM   8771  C  CE2 . PHE C 2 103 ? 155.941 137.776 119.649 1.00 63.47  ? 103 PHE C CE2 1 
ATOM   8772  C  CZ  . PHE C 2 103 ? 156.008 137.424 120.971 1.00 63.47  ? 103 PHE C CZ  1 
ATOM   8773  N  N   . ASP C 2 104 ? 151.952 139.224 117.148 1.00 69.19  ? 104 ASP C N   1 
ATOM   8774  C  CA  . ASP C 2 104 ? 151.947 138.267 116.052 1.00 69.19  ? 104 ASP C CA  1 
ATOM   8775  C  C   . ASP C 2 104 ? 153.122 137.308 116.178 1.00 69.19  ? 104 ASP C C   1 
ATOM   8776  O  O   . ASP C 2 104 ? 154.282 137.687 115.998 1.00 69.19  ? 104 ASP C O   1 
ATOM   8777  C  CB  . ASP C 2 104 ? 151.984 139.003 114.717 1.00 69.19  ? 104 ASP C CB  1 
ATOM   8778  C  CG  . ASP C 2 104 ? 150.664 139.670 114.394 1.00 69.19  ? 104 ASP C CG  1 
ATOM   8779  O  OD1 . ASP C 2 104 ? 149.615 139.085 114.732 1.00 69.19  ? 104 ASP C OD1 1 
ATOM   8780  O  OD2 . ASP C 2 104 ? 150.670 140.788 113.842 1.00 69.19  ? 104 ASP C OD2 1 
ATOM   8781  N  N   . GLY C 2 105 ? 152.806 136.055 116.488 1.00 65.08  ? 105 GLY C N   1 
ATOM   8782  C  CA  . GLY C 2 105 ? 153.811 135.077 116.845 1.00 65.08  ? 105 GLY C CA  1 
ATOM   8783  C  C   . GLY C 2 105 ? 153.606 134.472 118.211 1.00 65.08  ? 105 GLY C C   1 
ATOM   8784  O  O   . GLY C 2 105 ? 152.814 133.533 118.342 1.00 65.08  ? 105 GLY C O   1 
ATOM   8785  N  N   . LEU C 2 106 ? 154.293 134.986 119.235 1.00 63.61  ? 106 LEU C N   1 
ATOM   8786  C  CA  . LEU C 2 106 ? 154.027 134.590 120.616 1.00 63.61  ? 106 LEU C CA  1 
ATOM   8787  C  C   . LEU C 2 106 ? 154.238 133.095 120.820 1.00 63.61  ? 106 LEU C C   1 
ATOM   8788  O  O   . LEU C 2 106 ? 155.278 132.662 121.331 1.00 63.61  ? 106 LEU C O   1 
ATOM   8789  C  CB  . LEU C 2 106 ? 152.609 135.003 121.017 1.00 63.61  ? 106 LEU C CB  1 
ATOM   8790  C  CG  . LEU C 2 106 ? 152.190 134.681 122.450 1.00 63.61  ? 106 LEU C CG  1 
ATOM   8791  C  CD1 . LEU C 2 106 ? 153.118 135.362 123.415 1.00 63.61  ? 106 LEU C CD1 1 
ATOM   8792  C  CD2 . LEU C 2 106 ? 150.772 135.138 122.691 1.00 63.61  ? 106 LEU C CD2 1 
ATOM   8793  N  N   . PHE C 2 107 ? 153.255 132.286 120.424 1.00 64.78  ? 107 PHE C N   1 
ATOM   8794  C  CA  . PHE C 2 107 ? 153.311 130.868 120.751 1.00 64.78  ? 107 PHE C CA  1 
ATOM   8795  C  C   . PHE C 2 107 ? 154.355 130.139 119.918 1.00 64.78  ? 107 PHE C C   1 
ATOM   8796  O  O   . PHE C 2 107 ? 154.842 129.081 120.329 1.00 64.78  ? 107 PHE C O   1 
ATOM   8797  C  CB  . PHE C 2 107 ? 151.936 130.233 120.574 1.00 64.78  ? 107 PHE C CB  1 
ATOM   8798  C  CG  . PHE C 2 107 ? 151.858 128.826 121.072 1.00 64.78  ? 107 PHE C CG  1 
ATOM   8799  C  CD1 . PHE C 2 107 ? 151.879 128.561 122.427 1.00 64.78  ? 107 PHE C CD1 1 
ATOM   8800  C  CD2 . PHE C 2 107 ? 151.757 127.770 120.192 1.00 64.78  ? 107 PHE C CD2 1 
ATOM   8801  C  CE1 . PHE C 2 107 ? 151.808 127.266 122.892 1.00 64.78  ? 107 PHE C CE1 1 
ATOM   8802  C  CE2 . PHE C 2 107 ? 151.675 126.476 120.654 1.00 64.78  ? 107 PHE C CE2 1 
ATOM   8803  C  CZ  . PHE C 2 107 ? 151.709 126.223 122.002 1.00 64.78  ? 107 PHE C CZ  1 
ATOM   8804  N  N   . GLU C 2 108 ? 154.724 130.688 118.760 1.00 62.91  ? 108 GLU C N   1 
ATOM   8805  C  CA  . GLU C 2 108 ? 155.826 130.111 117.998 1.00 62.91  ? 108 GLU C CA  1 
ATOM   8806  C  C   . GLU C 2 108 ? 157.167 130.495 118.608 1.00 62.91  ? 108 GLU C C   1 
ATOM   8807  O  O   . GLU C 2 108 ? 158.124 129.713 118.573 1.00 62.91  ? 108 GLU C O   1 
ATOM   8808  C  CB  . GLU C 2 108 ? 155.744 130.556 116.540 1.00 62.91  ? 108 GLU C CB  1 
ATOM   8809  C  CG  . GLU C 2 108 ? 154.536 130.005 115.809 1.00 62.91  ? 108 GLU C CG  1 
ATOM   8810  C  CD  . GLU C 2 108 ? 154.468 130.462 114.368 1.00 62.91  ? 108 GLU C CD  1 
ATOM   8811  O  OE1 . GLU C 2 108 ? 155.298 131.307 113.972 1.00 62.91  ? 108 GLU C OE1 1 
ATOM   8812  O  OE2 . GLU C 2 108 ? 153.585 129.976 113.632 1.00 62.91  ? 108 GLU C OE2 1 
ATOM   8813  N  N   . PHE C 2 109 ? 157.251 131.702 119.172 1.00 58.40  ? 109 PHE C N   1 
ATOM   8814  C  CA  . PHE C 2 109 ? 158.424 132.089 119.949 1.00 58.40  ? 109 PHE C CA  1 
ATOM   8815  C  C   . PHE C 2 109 ? 158.614 131.164 121.147 1.00 58.40  ? 109 PHE C C   1 
ATOM   8816  O  O   . PHE C 2 109 ? 159.731 130.698 121.417 1.00 58.40  ? 109 PHE C O   1 
ATOM   8817  C  CB  . PHE C 2 109 ? 158.273 133.547 120.389 1.00 58.40  ? 109 PHE C CB  1 
ATOM   8818  C  CG  . PHE C 2 109 ? 159.410 134.063 121.216 1.00 58.40  ? 109 PHE C CG  1 
ATOM   8819  C  CD1 . PHE C 2 109 ? 160.638 134.327 120.642 1.00 58.40  ? 109 PHE C CD1 1 
ATOM   8820  C  CD2 . PHE C 2 109 ? 159.240 134.318 122.565 1.00 58.40  ? 109 PHE C CD2 1 
ATOM   8821  C  CE1 . PHE C 2 109 ? 161.683 134.809 121.401 1.00 58.40  ? 109 PHE C CE1 1 
ATOM   8822  C  CE2 . PHE C 2 109 ? 160.281 134.802 123.328 1.00 58.40  ? 109 PHE C CE2 1 
ATOM   8823  C  CZ  . PHE C 2 109 ? 161.503 135.048 122.745 1.00 58.40  ? 109 PHE C CZ  1 
ATOM   8824  N  N   . CYS C 2 110 ? 157.525 130.868 121.862 1.00 57.33  ? 110 CYS C N   1 
ATOM   8825  C  CA  . CYS C 2 110 ? 157.605 129.955 122.997 1.00 57.33  ? 110 CYS C CA  1 
ATOM   8826  C  C   . CYS C 2 110 ? 157.953 128.542 122.547 1.00 57.33  ? 110 CYS C C   1 
ATOM   8827  O  O   . CYS C 2 110 ? 158.786 127.872 123.172 1.00 57.33  ? 110 CYS C O   1 
ATOM   8828  C  CB  . CYS C 2 110 ? 156.285 129.966 123.762 1.00 57.33  ? 110 CYS C CB  1 
ATOM   8829  S  SG  . CYS C 2 110 ? 155.875 131.567 124.475 1.00 57.33  ? 110 CYS C SG  1 
ATOM   8830  N  N   . GLN C 2 111 ? 157.320 128.068 121.468 1.00 59.03  ? 111 GLN C N   1 
ATOM   8831  C  CA  . GLN C 2 111 ? 157.698 126.780 120.894 1.00 59.03  ? 111 GLN C CA  1 
ATOM   8832  C  C   . GLN C 2 111 ? 159.185 126.729 120.580 1.00 59.03  ? 111 GLN C C   1 
ATOM   8833  O  O   . GLN C 2 111 ? 159.834 125.694 120.767 1.00 59.03  ? 111 GLN C O   1 
ATOM   8834  C  CB  . GLN C 2 111 ? 156.901 126.497 119.620 1.00 59.03  ? 111 GLN C CB  1 
ATOM   8835  C  CG  . GLN C 2 111 ? 155.445 126.110 119.798 1.00 59.03  ? 111 GLN C CG  1 
ATOM   8836  C  CD  . GLN C 2 111 ? 154.779 125.826 118.465 1.00 59.03  ? 111 GLN C CD  1 
ATOM   8837  O  OE1 . GLN C 2 111 ? 155.373 126.041 117.410 1.00 59.03  ? 111 GLN C OE1 1 
ATOM   8838  N  NE2 . GLN C 2 111 ? 153.558 125.314 118.505 1.00 59.03  ? 111 GLN C NE2 1 
ATOM   8839  N  N   . LEU C 2 112 ? 159.744 127.839 120.104 1.00 56.94  ? 112 LEU C N   1 
ATOM   8840  C  CA  . LEU C 2 112 ? 161.120 127.819 119.628 1.00 56.94  ? 112 LEU C CA  1 
ATOM   8841  C  C   . LEU C 2 112 ? 162.103 127.810 120.792 1.00 56.94  ? 112 LEU C C   1 
ATOM   8842  O  O   . LEU C 2 112 ? 163.016 126.975 120.843 1.00 56.94  ? 112 LEU C O   1 
ATOM   8843  C  CB  . LEU C 2 112 ? 161.359 129.015 118.711 1.00 56.94  ? 112 LEU C CB  1 
ATOM   8844  C  CG  . LEU C 2 112 ? 162.667 128.979 117.937 1.00 56.94  ? 112 LEU C CG  1 
ATOM   8845  C  CD1 . LEU C 2 112 ? 162.668 127.735 117.084 1.00 56.94  ? 112 LEU C CD1 1 
ATOM   8846  C  CD2 . LEU C 2 112 ? 162.781 130.207 117.069 1.00 56.94  ? 112 LEU C CD2 1 
ATOM   8847  N  N   . SER C 2 113 ? 161.922 128.725 121.748 1.00 49.82  ? 113 SER C N   1 
ATOM   8848  C  CA  . SER C 2 113 ? 162.805 128.756 122.910 1.00 49.82  ? 113 SER C CA  1 
ATOM   8849  C  C   . SER C 2 113 ? 162.699 127.468 123.719 1.00 49.82  ? 113 SER C C   1 
ATOM   8850  O  O   . SER C 2 113 ? 163.714 126.841 124.055 1.00 49.82  ? 113 SER C O   1 
ATOM   8851  C  CB  . SER C 2 113 ? 162.475 129.968 123.779 1.00 49.82  ? 113 SER C CB  1 
ATOM   8852  O  OG  . SER C 2 113 ? 162.719 131.172 123.079 1.00 49.82  ? 113 SER C OG  1 
ATOM   8853  N  N   . THR C 2 114 ? 161.470 127.051 124.036 1.00 51.44  ? 114 THR C N   1 
ATOM   8854  C  CA  . THR C 2 114 ? 161.287 125.836 124.822 1.00 51.44  ? 114 THR C CA  1 
ATOM   8855  C  C   . THR C 2 114 ? 161.815 124.614 124.082 1.00 51.44  ? 114 THR C C   1 
ATOM   8856  O  O   . THR C 2 114 ? 162.423 123.729 124.693 1.00 51.44  ? 114 THR C O   1 
ATOM   8857  C  CB  . THR C 2 114 ? 159.813 125.654 125.176 1.00 51.44  ? 114 THR C CB  1 
ATOM   8858  O  OG1 . THR C 2 114 ? 159.369 126.775 125.947 1.00 51.44  ? 114 THR C OG1 1 
ATOM   8859  C  CG2 . THR C 2 114 ? 159.618 124.390 125.989 1.00 51.44  ? 114 THR C CG2 1 
ATOM   8860  N  N   . GLY C 2 115 ? 161.604 124.551 122.767 1.00 51.10  ? 115 GLY C N   1 
ATOM   8861  C  CA  . GLY C 2 115 ? 162.131 123.433 122.002 1.00 51.10  ? 115 GLY C CA  1 
ATOM   8862  C  C   . GLY C 2 115 ? 163.645 123.374 122.026 1.00 51.10  ? 115 GLY C C   1 
ATOM   8863  O  O   . GLY C 2 115 ? 164.234 122.299 122.175 1.00 51.10  ? 115 GLY C O   1 
ATOM   8864  N  N   . GLY C 2 116 ? 164.295 124.530 121.895 1.00 48.53  ? 116 GLY C N   1 
ATOM   8865  C  CA  . GLY C 2 116 ? 165.747 124.553 121.957 1.00 48.53  ? 116 GLY C CA  1 
ATOM   8866  C  C   . GLY C 2 116 ? 166.281 124.126 123.309 1.00 48.53  ? 116 GLY C C   1 
ATOM   8867  O  O   . GLY C 2 116 ? 167.222 123.333 123.398 1.00 48.53  ? 116 GLY C O   1 
ATOM   8868  N  N   . SER C 2 117 ? 165.683 124.642 124.386 1.00 47.79  ? 117 SER C N   1 
ATOM   8869  C  CA  . SER C 2 117 ? 166.179 124.315 125.720 1.00 47.79  ? 117 SER C CA  1 
ATOM   8870  C  C   . SER C 2 117 ? 165.939 122.848 126.058 1.00 47.79  ? 117 SER C C   1 
ATOM   8871  O  O   . SER C 2 117 ? 166.849 122.150 126.527 1.00 47.79  ? 117 SER C O   1 
ATOM   8872  C  CB  . SER C 2 117 ? 165.521 125.222 126.757 1.00 47.79  ? 117 SER C CB  1 
ATOM   8873  O  OG  . SER C 2 117 ? 165.989 124.929 128.058 1.00 47.79  ? 117 SER C OG  1 
ATOM   8874  N  N   . VAL C 2 118 ? 164.720 122.360 125.817 1.00 48.19  ? 118 VAL C N   1 
ATOM   8875  C  CA  . VAL C 2 118 ? 164.389 120.975 126.135 1.00 48.19  ? 118 VAL C CA  1 
ATOM   8876  C  C   . VAL C 2 118 ? 165.224 120.010 125.303 1.00 48.19  ? 118 VAL C C   1 
ATOM   8877  O  O   . VAL C 2 118 ? 165.782 119.043 125.833 1.00 48.19  ? 118 VAL C O   1 
ATOM   8878  C  CB  . VAL C 2 118 ? 162.882 120.731 125.948 1.00 48.19  ? 118 VAL C CB  1 
ATOM   8879  C  CG1 . VAL C 2 118 ? 162.564 119.260 126.114 1.00 48.19  ? 118 VAL C CG1 1 
ATOM   8880  C  CG2 . VAL C 2 118 ? 162.092 121.554 126.946 1.00 48.19  ? 118 VAL C CG2 1 
ATOM   8881  N  N   . ALA C 2 119 ? 165.326 120.249 123.992 1.00 47.66  ? 119 ALA C N   1 
ATOM   8882  C  CA  . ALA C 2 119 ? 166.172 119.395 123.162 1.00 47.66  ? 119 ALA C CA  1 
ATOM   8883  C  C   . ALA C 2 119 ? 167.619 119.442 123.631 1.00 47.66  ? 119 ALA C C   1 
ATOM   8884  O  O   . ALA C 2 119 ? 168.327 118.425 123.611 1.00 47.66  ? 119 ALA C O   1 
ATOM   8885  C  CB  . ALA C 2 119 ? 166.071 119.818 121.698 1.00 47.66  ? 119 ALA C CB  1 
ATOM   8886  N  N   . SER C 2 120 ? 168.065 120.618 124.074 1.00 48.19  ? 120 SER C N   1 
ATOM   8887  C  CA  . SER C 2 120 ? 169.427 120.772 124.567 1.00 48.19  ? 120 SER C CA  1 
ATOM   8888  C  C   . SER C 2 120 ? 169.670 119.893 125.787 1.00 48.19  ? 120 SER C C   1 
ATOM   8889  O  O   . SER C 2 120 ? 170.720 119.250 125.904 1.00 48.19  ? 120 SER C O   1 
ATOM   8890  C  CB  . SER C 2 120 ? 169.689 122.239 124.893 1.00 48.19  ? 120 SER C CB  1 
ATOM   8891  O  OG  . SER C 2 120 ? 171.006 122.421 125.357 1.00 48.19  ? 120 SER C OG  1 
ATOM   8892  N  N   . ALA C 2 121 ? 168.703 119.846 126.706 1.00 47.70  ? 121 ALA C N   1 
ATOM   8893  C  CA  . ALA C 2 121 ? 168.843 118.967 127.864 1.00 47.70  ? 121 ALA C CA  1 
ATOM   8894  C  C   . ALA C 2 121 ? 168.783 117.499 127.457 1.00 47.70  ? 121 ALA C C   1 
ATOM   8895  O  O   . ALA C 2 121 ? 169.550 116.674 127.972 1.00 47.70  ? 121 ALA C O   1 
ATOM   8896  C  CB  . ALA C 2 121 ? 167.764 119.280 128.896 1.00 47.70  ? 121 ALA C CB  1 
ATOM   8897  N  N   . VAL C 2 122 ? 167.878 117.156 126.533 1.00 51.72  ? 122 VAL C N   1 
ATOM   8898  C  CA  . VAL C 2 122 ? 167.747 115.772 126.075 1.00 51.72  ? 122 VAL C CA  1 
ATOM   8899  C  C   . VAL C 2 122 ? 169.075 115.259 125.539 1.00 51.72  ? 122 VAL C C   1 
ATOM   8900  O  O   . VAL C 2 122 ? 169.514 114.152 125.872 1.00 51.72  ? 122 VAL C O   1 
ATOM   8901  C  CB  . VAL C 2 122 ? 166.640 115.651 125.014 1.00 51.72  ? 122 VAL C CB  1 
ATOM   8902  C  CG1 . VAL C 2 122 ? 166.644 114.258 124.411 1.00 51.72  ? 122 VAL C CG1 1 
ATOM   8903  C  CG2 . VAL C 2 122 ? 165.287 115.948 125.617 1.00 51.72  ? 122 VAL C CG2 1 
ATOM   8904  N  N   . LYS C 2 123 ? 169.732 116.048 124.691 1.00 54.87  ? 123 LYS C N   1 
ATOM   8905  C  CA  . LYS C 2 123 ? 171.056 115.646 124.233 1.00 54.87  ? 123 LYS C CA  1 
ATOM   8906  C  C   . LYS C 2 123 ? 172.083 115.711 125.355 1.00 54.87  ? 123 LYS C C   1 
ATOM   8907  O  O   . LYS C 2 123 ? 173.046 114.935 125.360 1.00 54.87  ? 123 LYS C O   1 
ATOM   8908  C  CB  . LYS C 2 123 ? 171.495 116.520 123.063 1.00 54.87  ? 123 LYS C CB  1 
ATOM   8909  C  CG  . LYS C 2 123 ? 172.881 116.199 122.554 1.00 54.87  ? 123 LYS C CG  1 
ATOM   8910  C  CD  . LYS C 2 123 ? 173.208 117.038 121.354 1.00 54.87  ? 123 LYS C CD  1 
ATOM   8911  C  CE  . LYS C 2 123 ? 173.270 118.495 121.765 1.00 54.87  ? 123 LYS C CE  1 
ATOM   8912  N  NZ  . LYS C 2 123 ? 174.384 118.771 122.711 1.00 54.87  ? 123 LYS C NZ  1 
ATOM   8913  N  N   . LEU C 2 124 ? 171.887 116.609 126.320 1.00 51.04  ? 124 LEU C N   1 
ATOM   8914  C  CA  . LEU C 2 124 ? 172.910 116.831 127.334 1.00 51.04  ? 124 LEU C CA  1 
ATOM   8915  C  C   . LEU C 2 124 ? 173.017 115.653 128.295 1.00 51.04  ? 124 LEU C C   1 
ATOM   8916  O  O   . LEU C 2 124 ? 174.121 115.303 128.729 1.00 51.04  ? 124 LEU C O   1 
ATOM   8917  C  CB  . LEU C 2 124 ? 172.616 118.124 128.092 1.00 51.04  ? 124 LEU C CB  1 
ATOM   8918  C  CG  . LEU C 2 124 ? 173.660 118.597 129.097 1.00 51.04  ? 124 LEU C CG  1 
ATOM   8919  C  CD1 . LEU C 2 124 ? 174.964 118.881 128.388 1.00 51.04  ? 124 LEU C CD1 1 
ATOM   8920  C  CD2 . LEU C 2 124 ? 173.159 119.838 129.801 1.00 51.04  ? 124 LEU C CD2 1 
ATOM   8921  N  N   . ASN C 2 125 ? 171.893 115.022 128.639 1.00 53.97  ? 125 ASN C N   1 
ATOM   8922  C  CA  . ASN C 2 125 ? 171.950 113.938 129.615 1.00 53.97  ? 125 ASN C CA  1 
ATOM   8923  C  C   . ASN C 2 125 ? 172.257 112.578 128.995 1.00 53.97  ? 125 ASN C C   1 
ATOM   8924  O  O   . ASN C 2 125 ? 172.320 111.586 129.728 1.00 53.97  ? 125 ASN C O   1 
ATOM   8925  C  CB  . ASN C 2 125 ? 170.647 113.868 130.425 1.00 53.97  ? 125 ASN C CB  1 
ATOM   8926  C  CG  . ASN C 2 125 ? 169.438 113.509 129.585 1.00 53.97  ? 125 ASN C CG  1 
ATOM   8927  O  OD1 . ASN C 2 125 ? 169.552 113.191 128.406 1.00 53.97  ? 125 ASN C OD1 1 
ATOM   8928  N  ND2 . ASN C 2 125 ? 168.264 113.556 130.199 1.00 53.97  ? 125 ASN C ND2 1 
ATOM   8929  N  N   . LYS C 2 126 ? 172.454 112.502 127.680 1.00 63.71  ? 126 LYS C N   1 
ATOM   8930  C  CA  . LYS C 2 126 ? 172.826 111.258 127.019 1.00 63.71  ? 126 LYS C CA  1 
ATOM   8931  C  C   . LYS C 2 126 ? 174.331 111.119 126.823 1.00 63.71  ? 126 LYS C C   1 
ATOM   8932  O  O   . LYS C 2 126 ? 174.769 110.200 126.123 1.00 63.71  ? 126 LYS C O   1 
ATOM   8933  C  CB  . LYS C 2 126 ? 172.121 111.140 125.667 1.00 63.71  ? 126 LYS C CB  1 
ATOM   8934  C  CG  . LYS C 2 126 ? 170.619 110.973 125.759 1.00 63.71  ? 126 LYS C CG  1 
ATOM   8935  C  CD  . LYS C 2 126 ? 170.010 110.773 124.383 1.00 63.71  ? 126 LYS C CD  1 
ATOM   8936  C  CE  . LYS C 2 126 ? 168.495 110.706 124.458 1.00 63.71  ? 126 LYS C CE  1 
ATOM   8937  N  NZ  . LYS C 2 126 ? 168.027 109.490 125.177 1.00 63.71  ? 126 LYS C NZ  1 
ATOM   8938  N  N   . GLN C 2 127 ? 175.122 112.015 127.415 1.00 71.20  ? 127 GLN C N   1 
ATOM   8939  C  CA  . GLN C 2 127 ? 176.584 111.956 127.361 1.00 71.20  ? 127 GLN C CA  1 
ATOM   8940  C  C   . GLN C 2 127 ? 177.107 112.007 125.927 1.00 71.20  ? 127 GLN C C   1 
ATOM   8941  O  O   . GLN C 2 127 ? 178.080 111.336 125.580 1.00 71.20  ? 127 GLN C O   1 
ATOM   8942  C  CB  . GLN C 2 127 ? 177.119 110.721 128.087 1.00 71.20  ? 127 GLN C CB  1 
ATOM   8943  C  CG  . GLN C 2 127 ? 176.922 110.752 129.589 1.00 71.20  ? 127 GLN C CG  1 
ATOM   8944  C  CD  . GLN C 2 127 ? 177.486 109.525 130.269 1.00 71.20  ? 127 GLN C CD  1 
ATOM   8945  O  OE1 . GLN C 2 127 ? 177.974 108.606 129.612 1.00 71.20  ? 127 GLN C OE1 1 
ATOM   8946  N  NE2 . GLN C 2 127 ? 177.426 109.503 131.595 1.00 71.20  ? 127 GLN C NE2 1 
ATOM   8947  N  N   . GLN C 2 128 ? 176.459 112.809 125.084 1.00 69.89  ? 128 GLN C N   1 
ATOM   8948  C  CA  . GLN C 2 128 ? 177.011 113.120 123.772 1.00 69.89  ? 128 GLN C CA  1 
ATOM   8949  C  C   . GLN C 2 128 ? 177.925 114.334 123.793 1.00 69.89  ? 128 GLN C C   1 
ATOM   8950  O  O   . GLN C 2 128 ? 179.145 114.179 123.681 1.00 69.89  ? 128 GLN C O   1 
ATOM   8951  C  CB  . GLN C 2 128 ? 175.893 113.357 122.750 1.00 69.89  ? 128 GLN C CB  1 
ATOM   8952  C  CG  . GLN C 2 128 ? 175.099 112.117 122.384 1.00 69.89  ? 128 GLN C CG  1 
ATOM   8953  C  CD  . GLN C 2 128 ? 174.044 112.398 121.331 1.00 69.89  ? 128 GLN C CD  1 
ATOM   8954  O  OE1 . GLN C 2 128 ? 173.870 113.539 120.901 1.00 69.89  ? 128 GLN C OE1 1 
ATOM   8955  N  NE2 . GLN C 2 128 ? 173.335 111.359 120.910 1.00 69.89  ? 128 GLN C NE2 1 
ATOM   8956  N  N   . THR C 2 129 ? 177.369 115.534 123.938 1.00 64.19  ? 129 THR C N   1 
ATOM   8957  C  CA  . THR C 2 129 ? 178.166 116.738 124.102 1.00 64.19  ? 129 THR C CA  1 
ATOM   8958  C  C   . THR C 2 129 ? 178.362 116.994 125.587 1.00 64.19  ? 129 THR C C   1 
ATOM   8959  O  O   . THR C 2 129 ? 177.808 116.287 126.432 1.00 64.19  ? 129 THR C O   1 
ATOM   8960  C  CB  . THR C 2 129 ? 177.511 117.953 123.437 1.00 64.19  ? 129 THR C CB  1 
ATOM   8961  O  OG1 . THR C 2 129 ? 176.234 118.199 124.038 1.00 64.19  ? 129 THR C OG1 1 
ATOM   8962  C  CG2 . THR C 2 129 ? 177.328 117.705 121.949 1.00 64.19  ? 129 THR C CG2 1 
ATOM   8963  N  N   . ASP C 2 130 ? 179.160 118.012 125.899 1.00 60.05  ? 130 ASP C N   1 
ATOM   8964  C  CA  . ASP C 2 130 ? 179.461 118.325 127.289 1.00 60.05  ? 130 ASP C CA  1 
ATOM   8965  C  C   . ASP C 2 130 ? 178.964 119.712 127.678 1.00 60.05  ? 130 ASP C C   1 
ATOM   8966  O  O   . ASP C 2 130 ? 178.506 119.911 128.808 1.00 60.05  ? 130 ASP C O   1 
ATOM   8967  C  CB  . ASP C 2 130 ? 180.968 118.209 127.532 1.00 60.05  ? 130 ASP C CB  1 
ATOM   8968  C  CG  . ASP C 2 130 ? 181.324 118.157 129.003 1.00 60.05  ? 130 ASP C CG  1 
ATOM   8969  O  OD1 . ASP C 2 130 ? 180.410 118.251 129.847 1.00 60.05  ? 130 ASP C OD1 1 
ATOM   8970  O  OD2 . ASP C 2 130 ? 182.523 118.006 129.318 1.00 60.05  ? 130 ASP C OD2 1 
ATOM   8971  N  N   . ILE C 2 131 ? 179.037 120.673 126.763 1.00 53.18  ? 131 ILE C N   1 
ATOM   8972  C  CA  . ILE C 2 131 ? 178.506 122.013 126.975 1.00 53.18  ? 131 ILE C CA  1 
ATOM   8973  C  C   . ILE C 2 131 ? 177.406 122.245 125.953 1.00 53.18  ? 131 ILE C C   1 
ATOM   8974  O  O   . ILE C 2 131 ? 177.577 121.930 124.770 1.00 53.18  ? 131 ILE C O   1 
ATOM   8975  C  CB  . ILE C 2 131 ? 179.602 123.086 126.861 1.00 53.18  ? 131 ILE C CB  1 
ATOM   8976  C  CG1 . ILE C 2 131 ? 180.657 122.877 127.943 1.00 53.18  ? 131 ILE C CG1 1 
ATOM   8977  C  CG2 . ILE C 2 131 ? 179.006 124.471 126.985 1.00 53.18  ? 131 ILE C CG2 1 
ATOM   8978  C  CD1 . ILE C 2 131 ? 181.878 123.730 127.765 1.00 53.18  ? 131 ILE C CD1 1 
ATOM   8979  N  N   . ALA C 2 132 ? 176.282 122.786 126.408 1.00 45.61  ? 132 ALA C N   1 
ATOM   8980  C  CA  . ALA C 2 132 ? 175.111 122.997 125.572 1.00 45.61  ? 132 ALA C CA  1 
ATOM   8981  C  C   . ALA C 2 132 ? 174.711 124.462 125.628 1.00 45.61  ? 132 ALA C C   1 
ATOM   8982  O  O   . ALA C 2 132 ? 174.321 124.961 126.688 1.00 45.61  ? 132 ALA C O   1 
ATOM   8983  C  CB  . ALA C 2 132 ? 173.957 122.106 126.020 1.00 45.61  ? 132 ALA C CB  1 
ATOM   8984  N  N   . VAL C 2 133 ? 174.799 125.140 124.488 1.00 44.09  ? 133 VAL C N   1 
ATOM   8985  C  CA  . VAL C 2 133 ? 174.617 126.583 124.401 1.00 44.09  ? 133 VAL C CA  1 
ATOM   8986  C  C   . VAL C 2 133 ? 173.249 126.865 123.797 1.00 44.09  ? 133 VAL C C   1 
ATOM   8987  O  O   . VAL C 2 133 ? 172.847 126.211 122.828 1.00 44.09  ? 133 VAL C O   1 
ATOM   8988  C  CB  . VAL C 2 133 ? 175.729 127.239 123.565 1.00 44.09  ? 133 VAL C CB  1 
ATOM   8989  C  CG1 . VAL C 2 133 ? 175.526 128.731 123.494 1.00 44.09  ? 133 VAL C CG1 1 
ATOM   8990  C  CG2 . VAL C 2 133 ? 177.092 126.910 124.137 1.00 44.09  ? 133 VAL C CG2 1 
ATOM   8991  N  N   . ASN C 2 134 ? 172.542 127.841 124.364 1.00 43.04  ? 134 ASN C N   1 
ATOM   8992  C  CA  . ASN C 2 134 ? 171.218 128.227 123.879 1.00 43.04  ? 134 ASN C CA  1 
ATOM   8993  C  C   . ASN C 2 134 ? 170.925 129.620 124.423 1.00 43.04  ? 134 ASN C C   1 
ATOM   8994  O  O   . ASN C 2 134 ? 170.572 129.761 125.596 1.00 43.04  ? 134 ASN C O   1 
ATOM   8995  C  CB  . ASN C 2 134 ? 170.156 127.230 124.317 1.00 43.04  ? 134 ASN C CB  1 
ATOM   8996  C  CG  . ASN C 2 134 ? 168.792 127.537 123.733 1.00 43.04  ? 134 ASN C CG  1 
ATOM   8997  O  OD1 . ASN C 2 134 ? 168.620 128.505 122.999 1.00 43.04  ? 134 ASN C OD1 1 
ATOM   8998  N  ND2 . ASN C 2 134 ? 167.811 126.715 124.067 1.00 43.04  ? 134 ASN C ND2 1 
ATOM   8999  N  N   . TRP C 2 135 ? 171.058 130.637 123.573 1.00 40.41  ? 135 TRP C N   1 
ATOM   9000  C  CA  . TRP C 2 135 ? 170.853 131.998 124.045 1.00 40.41  ? 135 TRP C CA  1 
ATOM   9001  C  C   . TRP C 2 135 ? 169.427 132.483 123.833 1.00 40.41  ? 135 TRP C C   1 
ATOM   9002  O  O   . TRP C 2 135 ? 169.122 133.629 124.175 1.00 40.41  ? 135 TRP C O   1 
ATOM   9003  C  CB  . TRP C 2 135 ? 171.821 132.959 123.357 1.00 40.41  ? 135 TRP C CB  1 
ATOM   9004  C  CG  . TRP C 2 135 ? 173.260 132.603 123.556 1.00 40.41  ? 135 TRP C CG  1 
ATOM   9005  C  CD1 . TRP C 2 135 ? 174.123 132.131 122.611 1.00 40.41  ? 135 TRP C CD1 1 
ATOM   9006  C  CD2 . TRP C 2 135 ? 173.986 132.612 124.791 1.00 40.41  ? 135 TRP C CD2 1 
ATOM   9007  N  NE1 . TRP C 2 135 ? 175.353 131.895 123.170 1.00 40.41  ? 135 TRP C NE1 1 
ATOM   9008  C  CE2 . TRP C 2 135 ? 175.293 132.172 124.510 1.00 40.41  ? 135 TRP C CE2 1 
ATOM   9009  C  CE3 . TRP C 2 135 ? 173.663 132.965 126.101 1.00 40.41  ? 135 TRP C CE3 1 
ATOM   9010  C  CZ2 . TRP C 2 135 ? 176.273 132.077 125.490 1.00 40.41  ? 135 TRP C CZ2 1 
ATOM   9011  C  CZ3 . TRP C 2 135 ? 174.636 132.870 127.070 1.00 40.41  ? 135 TRP C CZ3 1 
ATOM   9012  C  CH2 . TRP C 2 135 ? 175.925 132.432 126.761 1.00 40.41  ? 135 TRP C CH2 1 
ATOM   9013  N  N   . ALA C 2 136 ? 168.552 131.644 123.275 1.00 43.11  ? 136 ALA C N   1 
ATOM   9014  C  CA  . ALA C 2 136 ? 167.162 132.048 123.092 1.00 43.11  ? 136 ALA C CA  1 
ATOM   9015  C  C   . ALA C 2 136 ? 166.344 131.785 124.348 1.00 43.11  ? 136 ALA C C   1 
ATOM   9016  O  O   . ALA C 2 136 ? 165.599 132.659 124.805 1.00 43.11  ? 136 ALA C O   1 
ATOM   9017  C  CB  . ALA C 2 136 ? 166.553 131.325 121.892 1.00 43.11  ? 136 ALA C CB  1 
ATOM   9018  N  N   . GLY C 2 137 ? 166.472 130.593 124.923 1.00 44.14  ? 137 GLY C N   1 
ATOM   9019  C  CA  . GLY C 2 137 ? 165.746 130.233 126.122 1.00 44.14  ? 137 GLY C CA  1 
ATOM   9020  C  C   . GLY C 2 137 ? 166.287 130.932 127.351 1.00 44.14  ? 137 GLY C C   1 
ATOM   9021  O  O   . GLY C 2 137 ? 167.087 131.867 127.273 1.00 44.14  ? 137 GLY C O   1 
ATOM   9022  N  N   . GLY C 2 138 ? 165.839 130.460 128.508 1.00 44.60  ? 138 GLY C N   1 
ATOM   9023  C  CA  . GLY C 2 138 ? 166.214 131.051 129.773 1.00 44.60  ? 138 GLY C CA  1 
ATOM   9024  C  C   . GLY C 2 138 ? 165.210 132.017 130.356 1.00 44.60  ? 138 GLY C C   1 
ATOM   9025  O  O   . GLY C 2 138 ? 165.605 132.904 131.119 1.00 44.60  ? 138 GLY C O   1 
ATOM   9026  N  N   . LEU C 2 139 ? 163.932 131.872 130.027 1.00 50.55  ? 139 LEU C N   1 
ATOM   9027  C  CA  . LEU C 2 139 ? 162.885 132.771 130.503 1.00 50.55  ? 139 LEU C CA  1 
ATOM   9028  C  C   . LEU C 2 139 ? 162.460 132.320 131.894 1.00 50.55  ? 139 LEU C C   1 
ATOM   9029  O  O   . LEU C 2 139 ? 161.638 131.414 132.040 1.00 50.55  ? 139 LEU C O   1 
ATOM   9030  C  CB  . LEU C 2 139 ? 161.714 132.756 129.529 1.00 50.55  ? 139 LEU C CB  1 
ATOM   9031  C  CG  . LEU C 2 139 ? 162.043 133.210 128.103 1.00 50.55  ? 139 LEU C CG  1 
ATOM   9032  C  CD1 . LEU C 2 139 ? 160.846 133.018 127.183 1.00 50.55  ? 139 LEU C CD1 1 
ATOM   9033  C  CD2 . LEU C 2 139 ? 162.523 134.653 128.076 1.00 50.55  ? 139 LEU C CD2 1 
ATOM   9034  N  N   . HIS C 2 140 ? 163.009 132.958 132.927 1.00 46.76  ? 140 HIS C N   1 
ATOM   9035  C  CA  . HIS C 2 140 ? 162.924 132.452 134.290 1.00 46.76  ? 140 HIS C CA  1 
ATOM   9036  C  C   . HIS C 2 140 ? 161.876 133.141 135.153 1.00 46.76  ? 140 HIS C C   1 
ATOM   9037  O  O   . HIS C 2 140 ? 161.789 132.833 136.345 1.00 46.76  ? 140 HIS C O   1 
ATOM   9038  C  CB  . HIS C 2 140 ? 164.297 132.549 134.964 1.00 46.76  ? 140 HIS C CB  1 
ATOM   9039  C  CG  . HIS C 2 140 ? 164.874 133.930 134.977 1.00 46.76  ? 140 HIS C CG  1 
ATOM   9040  N  ND1 . HIS C 2 140 ? 164.670 134.818 136.010 1.00 46.76  ? 140 HIS C ND1 1 
ATOM   9041  C  CD2 . HIS C 2 140 ? 165.651 134.577 134.076 1.00 46.76  ? 140 HIS C CD2 1 
ATOM   9042  C  CE1 . HIS C 2 140 ? 165.304 135.947 135.751 1.00 46.76  ? 140 HIS C CE1 1 
ATOM   9043  N  NE2 . HIS C 2 140 ? 165.902 135.829 134.580 1.00 46.76  ? 140 HIS C NE2 1 
ATOM   9044  N  N   . HIS C 2 141 ? 161.073 134.048 134.599 1.00 49.04  ? 141 HIS C N   1 
ATOM   9045  C  CA  . HIS C 2 141 ? 160.008 134.665 135.381 1.00 49.04  ? 141 HIS C CA  1 
ATOM   9046  C  C   . HIS C 2 141 ? 158.640 134.041 135.156 1.00 49.04  ? 141 HIS C C   1 
ATOM   9047  O  O   . HIS C 2 141 ? 157.750 134.236 135.989 1.00 49.04  ? 141 HIS C O   1 
ATOM   9048  C  CB  . HIS C 2 141 ? 159.907 136.166 135.088 1.00 49.04  ? 141 HIS C CB  1 
ATOM   9049  C  CG  . HIS C 2 141 ? 161.016 136.981 135.675 1.00 49.04  ? 141 HIS C CG  1 
ATOM   9050  N  ND1 . HIS C 2 141 ? 162.152 137.314 134.971 1.00 49.04  ? 141 HIS C ND1 1 
ATOM   9051  C  CD2 . HIS C 2 141 ? 161.160 137.530 136.903 1.00 49.04  ? 141 HIS C CD2 1 
ATOM   9052  C  CE1 . HIS C 2 141 ? 162.944 138.040 135.738 1.00 49.04  ? 141 HIS C CE1 1 
ATOM   9053  N  NE2 . HIS C 2 141 ? 162.367 138.183 136.917 1.00 49.04  ? 141 HIS C NE2 1 
ATOM   9054  N  N   . ALA C 2 142 ? 158.444 133.310 134.063 1.00 54.05  ? 142 ALA C N   1 
ATOM   9055  C  CA  . ALA C 2 142 ? 157.143 132.716 133.790 1.00 54.05  ? 142 ALA C CA  1 
ATOM   9056  C  C   . ALA C 2 142 ? 156.798 131.682 134.850 1.00 54.05  ? 142 ALA C C   1 
ATOM   9057  O  O   . ALA C 2 142 ? 157.672 130.979 135.362 1.00 54.05  ? 142 ALA C O   1 
ATOM   9058  C  CB  . ALA C 2 142 ? 157.131 132.073 132.408 1.00 54.05  ? 142 ALA C CB  1 
ATOM   9059  N  N   . LYS C 2 143 ? 155.517 131.589 135.176 1.00 59.97  ? 143 LYS C N   1 
ATOM   9060  C  CA  . LYS C 2 143 ? 155.047 130.746 136.262 1.00 59.97  ? 143 LYS C CA  1 
ATOM   9061  C  C   . LYS C 2 143 ? 154.101 129.675 135.725 1.00 59.97  ? 143 LYS C C   1 
ATOM   9062  O  O   . LYS C 2 143 ? 153.776 129.637 134.536 1.00 59.97  ? 143 LYS C O   1 
ATOM   9063  C  CB  . LYS C 2 143 ? 154.390 131.606 137.340 1.00 59.97  ? 143 LYS C CB  1 
ATOM   9064  C  CG  . LYS C 2 143 ? 155.378 132.553 137.995 1.00 59.97  ? 143 LYS C CG  1 
ATOM   9065  C  CD  . LYS C 2 143 ? 154.736 133.435 139.035 1.00 59.97  ? 143 LYS C CD  1 
ATOM   9066  C  CE  . LYS C 2 143 ? 155.788 134.287 139.713 1.00 59.97  ? 143 LYS C CE  1 
ATOM   9067  N  NZ  . LYS C 2 143 ? 156.410 135.241 138.758 1.00 59.97  ? 143 LYS C NZ  1 
ATOM   9068  N  N   . LYS C 2 144 ? 153.653 128.802 136.631 1.00 64.64  ? 144 LYS C N   1 
ATOM   9069  C  CA  . LYS C 2 144 ? 152.984 127.573 136.215 1.00 64.64  ? 144 LYS C CA  1 
ATOM   9070  C  C   . LYS C 2 144 ? 151.671 127.855 135.497 1.00 64.64  ? 144 LYS C C   1 
ATOM   9071  O  O   . LYS C 2 144 ? 151.275 127.103 134.599 1.00 64.64  ? 144 LYS C O   1 
ATOM   9072  C  CB  . LYS C 2 144 ? 152.751 126.673 137.429 1.00 64.64  ? 144 LYS C CB  1 
ATOM   9073  C  CG  . LYS C 2 144 ? 152.154 125.314 137.096 1.00 64.64  ? 144 LYS C CG  1 
ATOM   9074  C  CD  . LYS C 2 144 ? 152.076 124.432 138.328 1.00 64.64  ? 144 LYS C CD  1 
ATOM   9075  C  CE  . LYS C 2 144 ? 151.365 123.124 138.037 1.00 64.64  ? 144 LYS C CE  1 
ATOM   9076  N  NZ  . LYS C 2 144 ? 152.144 122.257 137.116 1.00 64.64  ? 144 LYS C NZ  1 
ATOM   9077  N  N   . SER C 2 145 ? 150.980 128.934 135.870 1.00 70.52  ? 145 SER C N   1 
ATOM   9078  C  CA  . SER C 2 145 ? 149.681 129.233 135.280 1.00 70.52  ? 145 SER C CA  1 
ATOM   9079  C  C   . SER C 2 145 ? 149.498 130.719 134.994 1.00 70.52  ? 145 SER C C   1 
ATOM   9080  O  O   . SER C 2 145 ? 148.364 131.207 135.017 1.00 70.52  ? 145 SER C O   1 
ATOM   9081  C  CB  . SER C 2 145 ? 148.552 128.730 136.182 1.00 70.52  ? 145 SER C CB  1 
ATOM   9082  O  OG  . SER C 2 145 ? 147.285 129.037 135.628 1.00 70.52  ? 145 SER C OG  1 
ATOM   9083  N  N   . GLU C 2 146 ? 150.581 131.443 134.717 1.00 68.95  ? 146 GLU C N   1 
ATOM   9084  C  CA  . GLU C 2 146 ? 150.498 132.853 134.362 1.00 68.95  ? 146 GLU C CA  1 
ATOM   9085  C  C   . GLU C 2 146 ? 151.860 133.323 133.874 1.00 68.95  ? 146 GLU C C   1 
ATOM   9086  O  O   . GLU C 2 146 ? 152.894 132.772 134.257 1.00 68.95  ? 146 GLU C O   1 
ATOM   9087  C  CB  . GLU C 2 146 ? 150.037 133.713 135.544 1.00 68.95  ? 146 GLU C CB  1 
ATOM   9088  C  CG  . GLU C 2 146 ? 151.002 133.746 136.710 1.00 68.95  ? 146 GLU C CG  1 
ATOM   9089  C  CD  . GLU C 2 146 ? 150.476 134.565 137.872 1.00 68.95  ? 146 GLU C CD  1 
ATOM   9090  O  OE1 . GLU C 2 146 ? 149.346 135.086 137.773 1.00 68.95  ? 146 GLU C OE1 1 
ATOM   9091  O  OE2 . GLU C 2 146 ? 151.194 134.690 138.885 1.00 68.95  ? 146 GLU C OE2 1 
ATOM   9092  N  N   . ALA C 2 147 ? 151.846 134.342 133.022 1.00 63.89  ? 147 ALA C N   1 
ATOM   9093  C  CA  . ALA C 2 147 ? 153.070 134.962 132.544 1.00 63.89  ? 147 ALA C CA  1 
ATOM   9094  C  C   . ALA C 2 147 ? 153.530 136.037 133.521 1.00 63.89  ? 147 ALA C C   1 
ATOM   9095  O  O   . ALA C 2 147 ? 152.758 136.536 134.342 1.00 63.89  ? 147 ALA C O   1 
ATOM   9096  C  CB  . ALA C 2 147 ? 152.866 135.566 131.156 1.00 63.89  ? 147 ALA C CB  1 
ATOM   9097  N  N   . SER C 2 148 ? 154.808 136.393 133.421 1.00 55.62  ? 148 SER C N   1 
ATOM   9098  C  CA  . SER C 2 148 ? 155.377 137.392 134.313 1.00 55.62  ? 148 SER C CA  1 
ATOM   9099  C  C   . SER C 2 148 ? 156.698 137.876 133.743 1.00 55.62  ? 148 SER C C   1 
ATOM   9100  O  O   . SER C 2 148 ? 157.493 137.074 133.251 1.00 55.62  ? 148 SER C O   1 
ATOM   9101  C  CB  . SER C 2 148 ? 155.589 136.824 135.721 1.00 55.62  ? 148 SER C CB  1 
ATOM   9102  O  OG  . SER C 2 148 ? 156.183 137.785 136.576 1.00 55.62  ? 148 SER C OG  1 
ATOM   9103  N  N   . GLY C 2 149 ? 156.917 139.188 133.811 1.00 51.93  ? 149 GLY C N   1 
ATOM   9104  C  CA  . GLY C 2 149 ? 158.186 139.787 133.449 1.00 51.93  ? 149 GLY C CA  1 
ATOM   9105  C  C   . GLY C 2 149 ? 158.731 139.383 132.097 1.00 51.93  ? 149 GLY C C   1 
ATOM   9106  O  O   . GLY C 2 149 ? 159.790 138.753 132.018 1.00 51.93  ? 149 GLY C O   1 
ATOM   9107  N  N   . PHE C 2 150 ? 158.005 139.718 131.032 1.00 53.29  ? 150 PHE C N   1 
ATOM   9108  C  CA  . PHE C 2 150 ? 158.412 139.529 129.641 1.00 53.29  ? 150 PHE C CA  1 
ATOM   9109  C  C   . PHE C 2 150 ? 158.444 138.063 129.230 1.00 53.29  ? 150 PHE C C   1 
ATOM   9110  O  O   . PHE C 2 150 ? 158.699 137.760 128.059 1.00 53.29  ? 150 PHE C O   1 
ATOM   9111  C  CB  . PHE C 2 150 ? 159.784 140.160 129.365 1.00 53.29  ? 150 PHE C CB  1 
ATOM   9112  C  CG  . PHE C 2 150 ? 159.844 141.636 129.632 1.00 53.29  ? 150 PHE C CG  1 
ATOM   9113  C  CD1 . PHE C 2 150 ? 158.691 142.391 129.747 1.00 53.29  ? 150 PHE C CD1 1 
ATOM   9114  C  CD2 . PHE C 2 150 ? 161.062 142.264 129.794 1.00 53.29  ? 150 PHE C CD2 1 
ATOM   9115  C  CE1 . PHE C 2 150 ? 158.756 143.744 130.006 1.00 53.29  ? 150 PHE C CE1 1 
ATOM   9116  C  CE2 . PHE C 2 150 ? 161.131 143.614 130.050 1.00 53.29  ? 150 PHE C CE2 1 
ATOM   9117  C  CZ  . PHE C 2 150 ? 159.977 144.353 130.158 1.00 53.29  ? 150 PHE C CZ  1 
ATOM   9118  N  N   . CYS C 2 151 ? 158.194 137.145 130.159 1.00 54.04  ? 151 CYS C N   1 
ATOM   9119  C  CA  . CYS C 2 151 ? 158.349 135.716 129.931 1.00 54.04  ? 151 CYS C CA  1 
ATOM   9120  C  C   . CYS C 2 151 ? 156.981 135.051 129.928 1.00 54.04  ? 151 CYS C C   1 
ATOM   9121  O  O   . CYS C 2 151 ? 156.156 135.317 130.808 1.00 54.04  ? 151 CYS C O   1 
ATOM   9122  C  CB  . CYS C 2 151 ? 159.232 135.092 131.011 1.00 54.04  ? 151 CYS C CB  1 
ATOM   9123  S  SG  . CYS C 2 151 ? 160.898 135.781 131.096 1.00 54.04  ? 151 CYS C SG  1 
ATOM   9124  N  N   . TYR C 2 152 ? 156.746 134.181 128.949 1.00 60.14  ? 152 TYR C N   1 
ATOM   9125  C  CA  . TYR C 2 152 ? 155.467 133.493 128.819 1.00 60.14  ? 152 TYR C CA  1 
ATOM   9126  C  C   . TYR C 2 152 ? 155.507 132.067 129.347 1.00 60.14  ? 152 TYR C C   1 
ATOM   9127  O  O   . TYR C 2 152 ? 154.696 131.707 130.203 1.00 60.14  ? 152 TYR C O   1 
ATOM   9128  C  CB  . TYR C 2 152 ? 155.022 133.488 127.355 1.00 60.14  ? 152 TYR C CB  1 
ATOM   9129  C  CG  . TYR C 2 152 ? 154.755 134.871 126.817 1.00 60.14  ? 152 TYR C CG  1 
ATOM   9130  C  CD1 . TYR C 2 152 ? 153.549 135.511 127.055 1.00 60.14  ? 152 TYR C CD1 1 
ATOM   9131  C  CD2 . TYR C 2 152 ? 155.719 135.547 126.089 1.00 60.14  ? 152 TYR C CD2 1 
ATOM   9132  C  CE1 . TYR C 2 152 ? 153.309 136.779 126.572 1.00 60.14  ? 152 TYR C CE1 1 
ATOM   9133  C  CE2 . TYR C 2 152 ? 155.488 136.816 125.606 1.00 60.14  ? 152 TYR C CE2 1 
ATOM   9134  C  CZ  . TYR C 2 152 ? 154.284 137.428 125.850 1.00 60.14  ? 152 TYR C CZ  1 
ATOM   9135  O  OH  . TYR C 2 152 ? 154.058 138.692 125.361 1.00 60.14  ? 152 TYR C OH  1 
ATOM   9136  N  N   . VAL C 2 153 ? 156.431 131.247 128.856 1.00 55.78  ? 153 VAL C N   1 
ATOM   9137  C  CA  . VAL C 2 153 ? 156.654 129.905 129.375 1.00 55.78  ? 153 VAL C CA  1 
ATOM   9138  C  C   . VAL C 2 153 ? 158.028 129.873 130.025 1.00 55.78  ? 153 VAL C C   1 
ATOM   9139  O  O   . VAL C 2 153 ? 158.889 130.704 129.718 1.00 55.78  ? 153 VAL C O   1 
ATOM   9140  C  CB  . VAL C 2 153 ? 156.548 128.833 128.274 1.00 55.78  ? 153 VAL C CB  1 
ATOM   9141  C  CG1 . VAL C 2 153 ? 155.165 128.847 127.666 1.00 55.78  ? 153 VAL C CG1 1 
ATOM   9142  C  CG2 . VAL C 2 153 ? 157.601 129.068 127.219 1.00 55.78  ? 153 VAL C CG2 1 
ATOM   9143  N  N   . ASN C 2 154 ? 158.231 128.916 130.925 1.00 51.21  ? 154 ASN C N   1 
ATOM   9144  C  CA  . ASN C 2 154 ? 159.453 128.851 131.724 1.00 51.21  ? 154 ASN C CA  1 
ATOM   9145  C  C   . ASN C 2 154 ? 160.319 127.733 131.161 1.00 51.21  ? 154 ASN C C   1 
ATOM   9146  O  O   . ASN C 2 154 ? 160.198 126.571 131.544 1.00 51.21  ? 154 ASN C O   1 
ATOM   9147  C  CB  . ASN C 2 154 ? 159.110 128.637 133.191 1.00 51.21  ? 154 ASN C CB  1 
ATOM   9148  C  CG  . ASN C 2 154 ? 160.277 128.897 134.106 1.00 51.21  ? 154 ASN C CG  1 
ATOM   9149  O  OD1 . ASN C 2 154 ? 161.390 129.151 133.656 1.00 51.21  ? 154 ASN C OD1 1 
ATOM   9150  N  ND2 . ASN C 2 154 ? 160.021 128.870 135.406 1.00 51.21  ? 154 ASN C ND2 1 
ATOM   9151  N  N   . ASP C 2 155 ? 161.207 128.097 130.232 1.00 50.57  ? 155 ASP C N   1 
ATOM   9152  C  CA  . ASP C 2 155 ? 162.028 127.105 129.545 1.00 50.57  ? 155 ASP C CA  1 
ATOM   9153  C  C   . ASP C 2 155 ? 162.930 126.354 130.509 1.00 50.57  ? 155 ASP C C   1 
ATOM   9154  O  O   . ASP C 2 155 ? 163.206 125.165 130.308 1.00 50.57  ? 155 ASP C O   1 
ATOM   9155  C  CB  . ASP C 2 155 ? 162.876 127.790 128.478 1.00 50.57  ? 155 ASP C CB  1 
ATOM   9156  C  CG  . ASP C 2 155 ? 162.039 128.485 127.431 1.00 50.57  ? 155 ASP C CG  1 
ATOM   9157  O  OD1 . ASP C 2 155 ? 160.907 128.027 127.172 1.00 50.57  ? 155 ASP C OD1 1 
ATOM   9158  O  OD2 . ASP C 2 155 ? 162.506 129.503 126.879 1.00 50.57  ? 155 ASP C OD2 1 
ATOM   9159  N  N   . ILE C 2 156 ? 163.393 127.027 131.563 1.00 45.05  ? 156 ILE C N   1 
ATOM   9160  C  CA  . ILE C 2 156 ? 164.374 126.430 132.461 1.00 45.05  ? 156 ILE C CA  1 
ATOM   9161  C  C   . ILE C 2 156 ? 163.768 125.263 133.223 1.00 45.05  ? 156 ILE C C   1 
ATOM   9162  O  O   . ILE C 2 156 ? 164.404 124.218 133.392 1.00 45.05  ? 156 ILE C O   1 
ATOM   9163  C  CB  . ILE C 2 156 ? 164.930 127.494 133.417 1.00 45.05  ? 156 ILE C CB  1 
ATOM   9164  C  CG1 . ILE C 2 156 ? 165.578 128.612 132.613 1.00 45.05  ? 156 ILE C CG1 1 
ATOM   9165  C  CG2 . ILE C 2 156 ? 165.931 126.872 134.360 1.00 45.05  ? 156 ILE C CG2 1 
ATOM   9166  C  CD1 . ILE C 2 156 ? 165.966 129.789 133.433 1.00 45.05  ? 156 ILE C CD1 1 
ATOM   9167  N  N   . VAL C 2 157 ? 162.533 125.420 133.700 1.00 47.14  ? 157 VAL C N   1 
ATOM   9168  C  CA  . VAL C 2 157 ? 161.904 124.357 134.476 1.00 47.14  ? 157 VAL C CA  1 
ATOM   9169  C  C   . VAL C 2 157 ? 161.584 123.164 133.586 1.00 47.14  ? 157 VAL C C   1 
ATOM   9170  O  O   . VAL C 2 157 ? 161.604 122.015 134.035 1.00 47.14  ? 157 VAL C O   1 
ATOM   9171  C  CB  . VAL C 2 157 ? 160.655 124.895 135.195 1.00 47.14  ? 157 VAL C CB  1 
ATOM   9172  C  CG1 . VAL C 2 157 ? 159.931 123.784 135.910 1.00 47.14  ? 157 VAL C CG1 1 
ATOM   9173  C  CG2 . VAL C 2 157 ? 161.061 125.957 136.182 1.00 47.14  ? 157 VAL C CG2 1 
ATOM   9174  N  N   . LEU C 2 158 ? 161.308 123.408 132.306 1.00 48.61  ? 158 LEU C N   1 
ATOM   9175  C  CA  . LEU C 2 158 ? 161.128 122.292 131.383 1.00 48.61  ? 158 LEU C CA  1 
ATOM   9176  C  C   . LEU C 2 158 ? 162.450 121.571 131.139 1.00 48.61  ? 158 LEU C C   1 
ATOM   9177  O  O   . LEU C 2 158 ? 162.497 120.334 131.099 1.00 48.61  ? 158 LEU C O   1 
ATOM   9178  C  CB  . LEU C 2 158 ? 160.526 122.783 130.066 1.00 48.61  ? 158 LEU C CB  1 
ATOM   9179  C  CG  . LEU C 2 158 ? 159.006 122.967 129.969 1.00 48.61  ? 158 LEU C CG  1 
ATOM   9180  C  CD1 . LEU C 2 158 ? 158.299 121.653 130.199 1.00 48.61  ? 158 LEU C CD1 1 
ATOM   9181  C  CD2 . LEU C 2 158 ? 158.479 124.019 130.926 1.00 48.61  ? 158 LEU C CD2 1 
ATOM   9182  N  N   . ALA C 2 159 ? 163.540 122.330 130.992 1.00 45.11  ? 159 ALA C N   1 
ATOM   9183  C  CA  . ALA C 2 159 ? 164.848 121.716 130.786 1.00 45.11  ? 159 ALA C CA  1 
ATOM   9184  C  C   . ALA C 2 159 ? 165.286 120.914 132.004 1.00 45.11  ? 159 ALA C C   1 
ATOM   9185  O  O   . ALA C 2 159 ? 165.875 119.837 131.865 1.00 45.11  ? 159 ALA C O   1 
ATOM   9186  C  CB  . ALA C 2 159 ? 165.885 122.786 130.456 1.00 45.11  ? 159 ALA C CB  1 
ATOM   9187  N  N   . ILE C 2 160 ? 165.012 121.421 133.206 1.00 42.80  ? 160 ILE C N   1 
ATOM   9188  C  CA  . ILE C 2 160 ? 165.420 120.717 134.417 1.00 42.80  ? 160 ILE C CA  1 
ATOM   9189  C  C   . ILE C 2 160 ? 164.524 119.510 134.659 1.00 42.80  ? 160 ILE C C   1 
ATOM   9190  O  O   . ILE C 2 160 ? 165.001 118.437 135.046 1.00 42.80  ? 160 ILE C O   1 
ATOM   9191  C  CB  . ILE C 2 160 ? 165.426 121.674 135.620 1.00 42.80  ? 160 ILE C CB  1 
ATOM   9192  C  CG1 . ILE C 2 160 ? 166.465 122.775 135.419 1.00 42.80  ? 160 ILE C CG1 1 
ATOM   9193  C  CG2 . ILE C 2 160 ? 165.744 120.923 136.880 1.00 42.80  ? 160 ILE C CG2 1 
ATOM   9194  C  CD1 . ILE C 2 160 ? 166.397 123.876 136.451 1.00 42.80  ? 160 ILE C CD1 1 
ATOM   9195  N  N   . LEU C 2 161 ? 163.217 119.660 134.437 1.00 45.46  ? 161 LEU C N   1 
ATOM   9196  C  CA  . LEU C 2 161 ? 162.327 118.503 134.441 1.00 45.46  ? 161 LEU C CA  1 
ATOM   9197  C  C   . LEU C 2 161 ? 162.804 117.447 133.453 1.00 45.46  ? 161 LEU C C   1 
ATOM   9198  O  O   . LEU C 2 161 ? 162.540 116.253 133.628 1.00 45.46  ? 161 LEU C O   1 
ATOM   9199  C  CB  . LEU C 2 161 ? 160.893 118.932 134.122 1.00 45.46  ? 161 LEU C CB  1 
ATOM   9200  C  CG  . LEU C 2 161 ? 159.903 119.193 135.262 1.00 45.46  ? 161 LEU C CG  1 
ATOM   9201  C  CD1 . LEU C 2 161 ? 159.569 117.897 135.965 1.00 45.46  ? 161 LEU C CD1 1 
ATOM   9202  C  CD2 . LEU C 2 161 ? 160.433 120.177 136.268 1.00 45.46  ? 161 LEU C CD2 1 
ATOM   9203  N  N   . GLU C 2 162 ? 163.514 117.871 132.406 1.00 48.87  ? 162 GLU C N   1 
ATOM   9204  C  CA  . GLU C 2 162 ? 164.082 116.902 131.476 1.00 48.87  ? 162 GLU C CA  1 
ATOM   9205  C  C   . GLU C 2 162 ? 165.383 116.308 132.011 1.00 48.87  ? 162 GLU C C   1 
ATOM   9206  O  O   . GLU C 2 162 ? 165.687 115.137 131.759 1.00 48.87  ? 162 GLU C O   1 
ATOM   9207  C  CB  . GLU C 2 162 ? 164.308 117.556 130.115 1.00 48.87  ? 162 GLU C CB  1 
ATOM   9208  C  CG  . GLU C 2 162 ? 164.823 116.600 129.068 1.00 48.87  ? 162 GLU C CG  1 
ATOM   9209  C  CD  . GLU C 2 162 ? 163.814 115.526 128.717 1.00 48.87  ? 162 GLU C CD  1 
ATOM   9210  O  OE1 . GLU C 2 162 ? 162.598 115.784 128.838 1.00 48.87  ? 162 GLU C OE1 1 
ATOM   9211  O  OE2 . GLU C 2 162 ? 164.236 114.418 128.327 1.00 48.87  ? 162 GLU C OE2 1 
ATOM   9212  N  N   . LEU C 2 163 ? 166.165 117.097 132.755 1.00 44.90  ? 163 LEU C N   1 
ATOM   9213  C  CA  . LEU C 2 163 ? 167.452 116.607 133.245 1.00 44.90  ? 163 LEU C CA  1 
ATOM   9214  C  C   . LEU C 2 163 ? 167.279 115.648 134.414 1.00 44.90  ? 163 LEU C C   1 
ATOM   9215  O  O   . LEU C 2 163 ? 168.114 114.762 134.626 1.00 44.90  ? 163 LEU C O   1 
ATOM   9216  C  CB  . LEU C 2 163 ? 168.347 117.775 133.660 1.00 44.90  ? 163 LEU C CB  1 
ATOM   9217  C  CG  . LEU C 2 163 ? 168.918 118.698 132.587 1.00 44.90  ? 163 LEU C CG  1 
ATOM   9218  C  CD1 . LEU C 2 163 ? 169.632 119.862 133.241 1.00 44.90  ? 163 LEU C CD1 1 
ATOM   9219  C  CD2 . LEU C 2 163 ? 169.865 117.937 131.682 1.00 44.90  ? 163 LEU C CD2 1 
ATOM   9220  N  N   . LEU C 2 164 ? 166.206 115.809 135.189 1.00 45.51  ? 164 LEU C N   1 
ATOM   9221  C  CA  . LEU C 2 164 ? 166.021 114.988 136.379 1.00 45.51  ? 164 LEU C CA  1 
ATOM   9222  C  C   . LEU C 2 164 ? 165.662 113.546 136.047 1.00 45.51  ? 164 LEU C C   1 
ATOM   9223  O  O   . LEU C 2 164 ? 165.354 112.773 136.959 1.00 45.51  ? 164 LEU C O   1 
ATOM   9224  C  CB  . LEU C 2 164 ? 164.941 115.594 137.274 1.00 45.51  ? 164 LEU C CB  1 
ATOM   9225  C  CG  . LEU C 2 164 ? 165.262 116.945 137.908 1.00 45.51  ? 164 LEU C CG  1 
ATOM   9226  C  CD1 . LEU C 2 164 ? 164.055 117.473 138.655 1.00 45.51  ? 164 LEU C CD1 1 
ATOM   9227  C  CD2 . LEU C 2 164 ? 166.456 116.827 138.829 1.00 45.51  ? 164 LEU C CD2 1 
ATOM   9228  N  N   . LYS C 2 165 ? 165.688 113.169 134.768 1.00 48.11  ? 165 LYS C N   1 
ATOM   9229  C  CA  . LYS C 2 165 ? 165.386 111.791 134.404 1.00 48.11  ? 165 LYS C CA  1 
ATOM   9230  C  C   . LYS C 2 165 ? 166.624 110.909 134.484 1.00 48.11  ? 165 LYS C C   1 
ATOM   9231  O  O   . LYS C 2 165 ? 166.508 109.695 134.685 1.00 48.11  ? 165 LYS C O   1 
ATOM   9232  C  CB  . LYS C 2 165 ? 164.784 111.744 133.002 1.00 48.11  ? 165 LYS C CB  1 
ATOM   9233  C  CG  . LYS C 2 165 ? 163.389 112.340 132.911 1.00 48.11  ? 165 LYS C CG  1 
ATOM   9234  C  CD  . LYS C 2 165 ? 162.935 112.459 131.467 1.00 48.11  ? 165 LYS C CD  1 
ATOM   9235  C  CE  . LYS C 2 165 ? 162.679 111.095 130.855 1.00 48.11  ? 165 LYS C CE  1 
ATOM   9236  N  NZ  . LYS C 2 165 ? 162.122 111.196 129.479 1.00 48.11  ? 165 LYS C NZ  1 
ATOM   9237  N  N   . TYR C 2 166 ? 167.810 111.492 134.336 1.00 50.16  ? 166 TYR C N   1 
ATOM   9238  C  CA  . TYR C 2 166 ? 169.065 110.753 134.398 1.00 50.16  ? 166 TYR C CA  1 
ATOM   9239  C  C   . TYR C 2 166 ? 169.997 111.223 135.500 1.00 50.16  ? 166 TYR C C   1 
ATOM   9240  O  O   . TYR C 2 166 ? 170.957 110.520 135.821 1.00 50.16  ? 166 TYR C O   1 
ATOM   9241  C  CB  . TYR C 2 166 ? 169.811 110.842 133.061 1.00 50.16  ? 166 TYR C CB  1 
ATOM   9242  C  CG  . TYR C 2 166 ? 169.230 110.001 131.951 1.00 50.16  ? 166 TYR C CG  1 
ATOM   9243  C  CD1 . TYR C 2 166 ? 168.322 108.986 132.216 1.00 50.16  ? 166 TYR C CD1 1 
ATOM   9244  C  CD2 . TYR C 2 166 ? 169.602 110.216 130.633 1.00 50.16  ? 166 TYR C CD2 1 
ATOM   9245  C  CE1 . TYR C 2 166 ? 167.799 108.214 131.197 1.00 50.16  ? 166 TYR C CE1 1 
ATOM   9246  C  CE2 . TYR C 2 166 ? 169.084 109.452 129.611 1.00 50.16  ? 166 TYR C CE2 1 
ATOM   9247  C  CZ  . TYR C 2 166 ? 168.184 108.454 129.897 1.00 50.16  ? 166 TYR C CZ  1 
ATOM   9248  O  OH  . TYR C 2 166 ? 167.674 107.697 128.872 1.00 50.16  ? 166 TYR C OH  1 
ATOM   9249  N  N   . HIS C 2 167 ? 169.756 112.392 136.085 1.00 47.33  ? 167 HIS C N   1 
ATOM   9250  C  CA  . HIS C 2 167 ? 170.665 112.943 137.080 1.00 47.33  ? 167 HIS C CA  1 
ATOM   9251  C  C   . HIS C 2 167 ? 170.018 112.966 138.458 1.00 47.33  ? 167 HIS C C   1 
ATOM   9252  O  O   . HIS C 2 167 ? 168.835 113.287 138.601 1.00 47.33  ? 167 HIS C O   1 
ATOM   9253  C  CB  . HIS C 2 167 ? 171.106 114.353 136.684 1.00 47.33  ? 167 HIS C CB  1 
ATOM   9254  C  CG  . HIS C 2 167 ? 171.944 114.397 135.444 1.00 47.33  ? 167 HIS C CG  1 
ATOM   9255  N  ND1 . HIS C 2 167 ? 173.266 114.008 135.425 1.00 47.33  ? 167 HIS C ND1 1 
ATOM   9256  C  CD2 . HIS C 2 167 ? 171.650 114.786 134.181 1.00 47.33  ? 167 HIS C CD2 1 
ATOM   9257  C  CE1 . HIS C 2 167 ? 173.749 114.153 134.204 1.00 47.33  ? 167 HIS C CE1 1 
ATOM   9258  N  NE2 . HIS C 2 167 ? 172.788 114.624 133.431 1.00 47.33  ? 167 HIS C NE2 1 
ATOM   9259  N  N   . GLN C 2 168 ? 170.810 112.615 139.474 1.00 51.03  ? 168 GLN C N   1 
ATOM   9260  C  CA  . GLN C 2 168 ? 170.326 112.661 140.850 1.00 51.03  ? 168 GLN C CA  1 
ATOM   9261  C  C   . GLN C 2 168 ? 170.058 114.090 141.299 1.00 51.03  ? 168 GLN C C   1 
ATOM   9262  O  O   . GLN C 2 168 ? 168.955 114.406 141.758 1.00 51.03  ? 168 GLN C O   1 
ATOM   9263  C  CB  . GLN C 2 168 ? 171.336 111.994 141.784 1.00 51.03  ? 168 GLN C CB  1 
ATOM   9264  C  CG  . GLN C 2 168 ? 170.970 112.059 143.264 1.00 51.03  ? 168 GLN C CG  1 
ATOM   9265  C  CD  . GLN C 2 168 ? 169.765 111.214 143.618 1.00 51.03  ? 168 GLN C CD  1 
ATOM   9266  O  OE1 . GLN C 2 168 ? 169.633 110.082 143.159 1.00 51.03  ? 168 GLN C OE1 1 
ATOM   9267  N  NE2 . GLN C 2 168 ? 168.877 111.763 144.439 1.00 51.03  ? 168 GLN C NE2 1 
ATOM   9268  N  N   . ARG C 2 169 ? 171.051 114.965 141.180 1.00 50.04  ? 169 ARG C N   1 
ATOM   9269  C  CA  . ARG C 2 169 ? 170.965 116.322 141.694 1.00 50.04  ? 169 ARG C CA  1 
ATOM   9270  C  C   . ARG C 2 169 ? 171.376 117.305 140.611 1.00 50.04  ? 169 ARG C C   1 
ATOM   9271  O  O   . ARG C 2 169 ? 172.377 117.097 139.921 1.00 50.04  ? 169 ARG C O   1 
ATOM   9272  C  CB  . ARG C 2 169 ? 171.855 116.490 142.923 1.00 50.04  ? 169 ARG C CB  1 
ATOM   9273  C  CG  . ARG C 2 169 ? 171.395 115.688 144.123 1.00 50.04  ? 169 ARG C CG  1 
ATOM   9274  C  CD  . ARG C 2 169 ? 172.282 115.948 145.317 1.00 50.04  ? 169 ARG C CD  1 
ATOM   9275  N  NE  . ARG C 2 169 ? 173.654 115.527 145.052 1.00 50.04  ? 169 ARG C NE  1 
ATOM   9276  C  CZ  . ARG C 2 169 ? 174.101 114.290 145.231 1.00 50.04  ? 169 ARG C CZ  1 
ATOM   9277  N  NH1 . ARG C 2 169 ? 173.285 113.345 145.673 1.00 50.04  ? 169 ARG C NH1 1 
ATOM   9278  N  NH2 . ARG C 2 169 ? 175.365 113.996 144.965 1.00 50.04  ? 169 ARG C NH2 1 
ATOM   9279  N  N   . VAL C 2 170 ? 170.605 118.380 140.471 1.00 44.46  ? 170 VAL C N   1 
ATOM   9280  C  CA  . VAL C 2 170 ? 170.842 119.399 139.456 1.00 44.46  ? 170 VAL C CA  1 
ATOM   9281  C  C   . VAL C 2 170 ? 171.003 120.747 140.143 1.00 44.46  ? 170 VAL C C   1 
ATOM   9282  O  O   . VAL C 2 170 ? 170.207 121.101 141.022 1.00 44.46  ? 170 VAL C O   1 
ATOM   9283  C  CB  . VAL C 2 170 ? 169.701 119.449 138.423 1.00 44.46  ? 170 VAL C CB  1 
ATOM   9284  C  CG1 . VAL C 2 170 ? 169.901 120.600 137.462 1.00 44.46  ? 170 VAL C CG1 1 
ATOM   9285  C  CG2 . VAL C 2 170 ? 169.624 118.143 137.664 1.00 44.46  ? 170 VAL C CG2 1 
ATOM   9286  N  N   . LEU C 2 171 ? 172.026 121.494 139.743 1.00 39.74  ? 171 LEU C N   1 
ATOM   9287  C  CA  . LEU C 2 171 ? 172.268 122.831 140.260 1.00 39.74  ? 171 LEU C CA  1 
ATOM   9288  C  C   . LEU C 2 171 ? 171.829 123.859 139.228 1.00 39.74  ? 171 LEU C C   1 
ATOM   9289  O  O   . LEU C 2 171 ? 171.918 123.618 138.021 1.00 39.74  ? 171 LEU C O   1 
ATOM   9290  C  CB  . LEU C 2 171 ? 173.746 123.027 140.608 1.00 39.74  ? 171 LEU C CB  1 
ATOM   9291  C  CG  . LEU C 2 171 ? 174.159 124.343 141.274 1.00 39.74  ? 171 LEU C CG  1 
ATOM   9292  C  CD1 . LEU C 2 171 ? 173.492 124.492 142.623 1.00 39.74  ? 171 LEU C CD1 1 
ATOM   9293  C  CD2 . LEU C 2 171 ? 175.663 124.423 141.425 1.00 39.74  ? 171 LEU C CD2 1 
ATOM   9294  N  N   . TYR C 2 172 ? 171.341 124.996 139.708 1.00 40.13  ? 172 TYR C N   1 
ATOM   9295  C  CA  . TYR C 2 172 ? 170.919 126.107 138.868 1.00 40.13  ? 172 TYR C CA  1 
ATOM   9296  C  C   . TYR C 2 172 ? 171.570 127.383 139.377 1.00 40.13  ? 172 TYR C C   1 
ATOM   9297  O  O   . TYR C 2 172 ? 171.574 127.637 140.584 1.00 40.13  ? 172 TYR C O   1 
ATOM   9298  C  CB  . TYR C 2 172 ? 169.398 126.251 138.872 1.00 40.13  ? 172 TYR C CB  1 
ATOM   9299  C  CG  . TYR C 2 172 ? 168.897 127.465 138.127 1.00 40.13  ? 172 TYR C CG  1 
ATOM   9300  C  CD1 . TYR C 2 172 ? 168.886 127.504 136.743 1.00 40.13  ? 172 TYR C CD1 1 
ATOM   9301  C  CD2 . TYR C 2 172 ? 168.431 128.572 138.814 1.00 40.13  ? 172 TYR C CD2 1 
ATOM   9302  C  CE1 . TYR C 2 172 ? 168.430 128.613 136.069 1.00 40.13  ? 172 TYR C CE1 1 
ATOM   9303  C  CE2 . TYR C 2 172 ? 167.976 129.681 138.148 1.00 40.13  ? 172 TYR C CE2 1 
ATOM   9304  C  CZ  . TYR C 2 172 ? 167.972 129.695 136.777 1.00 40.13  ? 172 TYR C CZ  1 
ATOM   9305  O  OH  . TYR C 2 172 ? 167.515 130.805 136.111 1.00 40.13  ? 172 TYR C OH  1 
ATOM   9306  N  N   . ILE C 2 173 ? 172.114 128.183 138.465 1.00 41.74  ? 173 ILE C N   1 
ATOM   9307  C  CA  . ILE C 2 173 ? 172.850 129.390 138.824 1.00 41.74  ? 173 ILE C CA  1 
ATOM   9308  C  C   . ILE C 2 173 ? 172.225 130.578 138.106 1.00 41.74  ? 173 ILE C C   1 
ATOM   9309  O  O   . ILE C 2 173 ? 172.040 130.544 136.885 1.00 41.74  ? 173 ILE C O   1 
ATOM   9310  C  CB  . ILE C 2 173 ? 174.341 129.268 138.470 1.00 41.74  ? 173 ILE C CB  1 
ATOM   9311  C  CG1 . ILE C 2 173 ? 174.957 128.058 139.163 1.00 41.74  ? 173 ILE C CG1 1 
ATOM   9312  C  CG2 . ILE C 2 173 ? 175.076 130.525 138.886 1.00 41.74  ? 173 ILE C CG2 1 
ATOM   9313  C  CD1 . ILE C 2 173 ? 176.298 127.681 138.604 1.00 41.74  ? 173 ILE C CD1 1 
ATOM   9314  N  N   . ASP C 2 174 ? 171.918 131.629 138.862 1.00 46.47  ? 174 ASP C N   1 
ATOM   9315  C  CA  . ASP C 2 174 ? 171.283 132.832 138.342 1.00 46.47  ? 174 ASP C CA  1 
ATOM   9316  C  C   . ASP C 2 174 ? 172.233 134.011 138.481 1.00 46.47  ? 174 ASP C C   1 
ATOM   9317  O  O   . ASP C 2 174 ? 172.535 134.444 139.600 1.00 46.47  ? 174 ASP C O   1 
ATOM   9318  C  CB  . ASP C 2 174 ? 169.976 133.127 139.080 1.00 46.47  ? 174 ASP C CB  1 
ATOM   9319  C  CG  . ASP C 2 174 ? 169.211 134.289 138.479 1.00 46.47  ? 174 ASP C CG  1 
ATOM   9320  O  OD1 . ASP C 2 174 ? 169.660 134.840 137.454 1.00 46.47  ? 174 ASP C OD1 1 
ATOM   9321  O  OD2 . ASP C 2 174 ? 168.168 134.672 139.048 1.00 46.47  ? 174 ASP C OD2 1 
ATOM   9322  N  N   . ILE C 2 175 ? 172.686 134.534 137.343 1.00 45.35  ? 175 ILE C N   1 
ATOM   9323  C  CA  . ILE C 2 175 ? 173.553 135.703 137.289 1.00 45.35  ? 175 ILE C CA  1 
ATOM   9324  C  C   . ILE C 2 175 ? 172.784 136.979 136.980 1.00 45.35  ? 175 ILE C C   1 
ATOM   9325  O  O   . ILE C 2 175 ? 173.252 138.071 137.320 1.00 45.35  ? 175 ILE C O   1 
ATOM   9326  C  CB  . ILE C 2 175 ? 174.689 135.499 136.266 1.00 45.35  ? 175 ILE C CB  1 
ATOM   9327  C  CG1 . ILE C 2 175 ? 175.500 134.256 136.605 1.00 45.35  ? 175 ILE C CG1 1 
ATOM   9328  C  CG2 . ILE C 2 175 ? 175.646 136.657 136.270 1.00 45.35  ? 175 ILE C CG2 1 
ATOM   9329  C  CD1 . ILE C 2 175 ? 176.515 133.915 135.541 1.00 45.35  ? 175 ILE C CD1 1 
ATOM   9330  N  N   . ASP C 2 176 ? 171.602 136.869 136.375 1.00 44.72  ? 176 ASP C N   1 
ATOM   9331  C  CA  . ASP C 2 176 ? 170.802 138.027 135.992 1.00 44.72  ? 176 ASP C CA  1 
ATOM   9332  C  C   . ASP C 2 176 ? 170.553 138.957 137.179 1.00 44.72  ? 176 ASP C C   1 
ATOM   9333  O  O   . ASP C 2 176 ? 170.539 138.537 138.339 1.00 44.72  ? 176 ASP C O   1 
ATOM   9334  C  CB  . ASP C 2 176 ? 169.470 137.557 135.403 1.00 44.72  ? 176 ASP C CB  1 
ATOM   9335  C  CG  . ASP C 2 176 ? 168.679 138.679 134.762 1.00 44.72  ? 176 ASP C CG  1 
ATOM   9336  O  OD1 . ASP C 2 176 ? 169.145 139.835 134.763 1.00 44.72  ? 176 ASP C OD1 1 
ATOM   9337  O  OD2 . ASP C 2 176 ? 167.574 138.403 134.258 1.00 44.72  ? 176 ASP C OD2 1 
ATOM   9338  N  N   . ILE C 2 177 ? 170.361 140.244 136.869 1.00 42.00  ? 177 ILE C N   1 
ATOM   9339  C  CA  . ILE C 2 177 ? 170.083 141.255 137.889 1.00 42.00  ? 177 ILE C CA  1 
ATOM   9340  C  C   . ILE C 2 177 ? 168.841 140.905 138.694 1.00 42.00  ? 177 ILE C C   1 
ATOM   9341  O  O   . ILE C 2 177 ? 168.743 141.254 139.876 1.00 42.00  ? 177 ILE C O   1 
ATOM   9342  C  CB  . ILE C 2 177 ? 169.947 142.641 137.225 1.00 42.00  ? 177 ILE C CB  1 
ATOM   9343  C  CG1 . ILE C 2 177 ? 169.807 143.762 138.248 1.00 42.00  ? 177 ILE C CG1 1 
ATOM   9344  C  CG2 . ILE C 2 177 ? 168.762 142.689 136.330 1.00 42.00  ? 177 ILE C CG2 1 
ATOM   9345  C  CD1 . ILE C 2 177 ? 171.035 144.062 138.968 1.00 42.00  ? 177 ILE C CD1 1 
ATOM   9346  N  N   . HIS C 2 178 ? 167.884 140.211 138.088 1.00 42.18  ? 178 HIS C N   1 
ATOM   9347  C  CA  . HIS C 2 178 ? 166.611 139.956 138.739 1.00 42.18  ? 178 HIS C CA  1 
ATOM   9348  C  C   . HIS C 2 178 ? 166.628 138.618 139.472 1.00 42.18  ? 178 HIS C C   1 
ATOM   9349  O  O   . HIS C 2 178 ? 167.542 137.805 139.331 1.00 42.18  ? 178 HIS C O   1 
ATOM   9350  C  CB  . HIS C 2 178 ? 165.466 139.979 137.726 1.00 42.18  ? 178 HIS C CB  1 
ATOM   9351  C  CG  . HIS C 2 178 ? 165.268 141.305 137.064 1.00 42.18  ? 178 HIS C CG  1 
ATOM   9352  N  ND1 . HIS C 2 178 ? 165.795 141.608 135.828 1.00 42.18  ? 178 HIS C ND1 1 
ATOM   9353  C  CD2 . HIS C 2 178 ? 164.619 142.418 137.479 1.00 42.18  ? 178 HIS C CD2 1 
ATOM   9354  C  CE1 . HIS C 2 178 ? 165.466 142.846 135.503 1.00 42.18  ? 178 HIS C CE1 1 
ATOM   9355  N  NE2 . HIS C 2 178 ? 164.755 143.360 136.489 1.00 42.18  ? 178 HIS C NE2 1 
ATOM   9356  N  N   . HIS C 2 179 ? 165.584 138.398 140.263 1.00 46.81  ? 179 HIS C N   1 
ATOM   9357  C  CA  . HIS C 2 179 ? 165.428 137.155 141.001 1.00 46.81  ? 179 HIS C CA  1 
ATOM   9358  C  C   . HIS C 2 179 ? 164.612 136.155 140.195 1.00 46.81  ? 179 HIS C C   1 
ATOM   9359  O  O   . HIS C 2 179 ? 163.418 136.361 139.956 1.00 46.81  ? 179 HIS C O   1 
ATOM   9360  C  CB  . HIS C 2 179 ? 164.762 137.429 142.348 1.00 46.81  ? 179 HIS C CB  1 
ATOM   9361  C  CG  . HIS C 2 179 ? 164.466 136.196 143.141 1.00 46.81  ? 179 HIS C CG  1 
ATOM   9362  N  ND1 . HIS C 2 179 ? 163.255 135.543 143.067 1.00 46.81  ? 179 HIS C ND1 1 
ATOM   9363  C  CD2 . HIS C 2 179 ? 165.223 135.485 144.009 1.00 46.81  ? 179 HIS C CD2 1 
ATOM   9364  C  CE1 . HIS C 2 179 ? 163.272 134.494 143.867 1.00 46.81  ? 179 HIS C CE1 1 
ATOM   9365  N  NE2 . HIS C 2 179 ? 164.456 134.434 144.448 1.00 46.81  ? 179 HIS C NE2 1 
ATOM   9366  N  N   . GLY C 2 180 ? 165.260 135.072 139.775 1.00 46.53  ? 180 GLY C N   1 
ATOM   9367  C  CA  . GLY C 2 180 ? 164.571 134.003 139.084 1.00 46.53  ? 180 GLY C CA  1 
ATOM   9368  C  C   . GLY C 2 180 ? 163.522 133.348 139.952 1.00 46.53  ? 180 GLY C C   1 
ATOM   9369  O  O   . GLY C 2 180 ? 163.756 132.278 140.519 1.00 46.53  ? 180 GLY C O   1 
ATOM   9370  N  N   . ASP C 2 181 ? 162.351 133.979 140.054 1.00 50.59  ? 181 ASP C N   1 
ATOM   9371  C  CA  . ASP C 2 181 ? 161.343 133.520 141.001 1.00 50.59  ? 181 ASP C CA  1 
ATOM   9372  C  C   . ASP C 2 181 ? 160.500 132.381 140.444 1.00 50.59  ? 181 ASP C C   1 
ATOM   9373  O  O   . ASP C 2 181 ? 159.867 131.651 141.215 1.00 50.59  ? 181 ASP C O   1 
ATOM   9374  C  CB  . ASP C 2 181 ? 160.453 134.690 141.417 1.00 50.59  ? 181 ASP C CB  1 
ATOM   9375  C  CG  . ASP C 2 181 ? 159.757 135.344 140.239 1.00 50.59  ? 181 ASP C CG  1 
ATOM   9376  O  OD1 . ASP C 2 181 ? 160.020 134.942 139.087 1.00 50.59  ? 181 ASP C OD1 1 
ATOM   9377  O  OD2 . ASP C 2 181 ? 158.942 136.262 140.466 1.00 50.59  ? 181 ASP C OD2 1 
ATOM   9378  N  N   . GLY C 2 182 ? 160.470 132.211 139.122 1.00 49.99  ? 182 GLY C N   1 
ATOM   9379  C  CA  . GLY C 2 182 ? 159.674 131.138 138.550 1.00 49.99  ? 182 GLY C CA  1 
ATOM   9380  C  C   . GLY C 2 182 ? 160.344 129.786 138.690 1.00 49.99  ? 182 GLY C C   1 
ATOM   9381  O  O   . GLY C 2 182 ? 159.694 128.780 138.989 1.00 49.99  ? 182 GLY C O   1 
ATOM   9382  N  N   . VAL C 2 183 ? 161.661 129.746 138.483 1.00 48.26  ? 183 VAL C N   1 
ATOM   9383  C  CA  . VAL C 2 183 ? 162.392 128.489 138.585 1.00 48.26  ? 183 VAL C CA  1 
ATOM   9384  C  C   . VAL C 2 183 ? 162.735 128.185 140.038 1.00 48.26  ? 183 VAL C C   1 
ATOM   9385  O  O   . VAL C 2 183 ? 162.928 127.022 140.411 1.00 48.26  ? 183 VAL C O   1 
ATOM   9386  C  CB  . VAL C 2 183 ? 163.646 128.533 137.695 1.00 48.26  ? 183 VAL C CB  1 
ATOM   9387  C  CG1 . VAL C 2 183 ? 164.580 129.614 138.175 1.00 48.26  ? 183 VAL C CG1 1 
ATOM   9388  C  CG2 . VAL C 2 183 ? 164.345 127.185 137.678 1.00 48.26  ? 183 VAL C CG2 1 
ATOM   9389  N  N   . GLU C 2 184 ? 162.817 129.213 140.885 1.00 49.27  ? 184 GLU C N   1 
ATOM   9390  C  CA  . GLU C 2 184 ? 162.979 128.955 142.312 1.00 49.27  ? 184 GLU C CA  1 
ATOM   9391  C  C   . GLU C 2 184 ? 161.656 128.548 142.940 1.00 49.27  ? 184 GLU C C   1 
ATOM   9392  O  O   . GLU C 2 184 ? 161.622 127.721 143.858 1.00 49.27  ? 184 GLU C O   1 
ATOM   9393  C  CB  . GLU C 2 184 ? 163.558 130.176 143.022 1.00 49.27  ? 184 GLU C CB  1 
ATOM   9394  C  CG  . GLU C 2 184 ? 163.746 129.965 144.518 1.00 49.27  ? 184 GLU C CG  1 
ATOM   9395  C  CD  . GLU C 2 184 ? 164.463 131.116 145.188 1.00 49.27  ? 184 GLU C CD  1 
ATOM   9396  O  OE1 . GLU C 2 184 ? 164.846 132.067 144.480 1.00 49.27  ? 184 GLU C OE1 1 
ATOM   9397  O  OE2 . GLU C 2 184 ? 164.640 131.070 146.423 1.00 49.27  ? 184 GLU C OE2 1 
ATOM   9398  N  N   . GLU C 2 185 ? 160.553 129.116 142.456 1.00 51.64  ? 185 GLU C N   1 
ATOM   9399  C  CA  . GLU C 2 185 ? 159.244 128.690 142.934 1.00 51.64  ? 185 GLU C CA  1 
ATOM   9400  C  C   . GLU C 2 185 ? 158.932 127.272 142.482 1.00 51.64  ? 185 GLU C C   1 
ATOM   9401  O  O   . GLU C 2 185 ? 158.423 126.464 143.263 1.00 51.64  ? 185 GLU C O   1 
ATOM   9402  C  CB  . GLU C 2 185 ? 158.169 129.659 142.450 1.00 51.64  ? 185 GLU C CB  1 
ATOM   9403  C  CG  . GLU C 2 185 ? 156.776 129.343 142.947 1.00 51.64  ? 185 GLU C CG  1 
ATOM   9404  C  CD  . GLU C 2 185 ? 155.767 130.375 142.501 1.00 51.64  ? 185 GLU C CD  1 
ATOM   9405  O  OE1 . GLU C 2 185 ? 156.168 131.322 141.793 1.00 51.64  ? 185 GLU C OE1 1 
ATOM   9406  O  OE2 . GLU C 2 185 ? 154.577 130.245 142.856 1.00 51.64  ? 185 GLU C OE2 1 
ATOM   9407  N  N   . ALA C 2 186 ? 159.247 126.944 141.227 1.00 48.35  ? 186 ALA C N   1 
ATOM   9408  C  CA  . ALA C 2 186 ? 158.886 125.632 140.700 1.00 48.35  ? 186 ALA C CA  1 
ATOM   9409  C  C   . ALA C 2 186 ? 159.630 124.503 141.404 1.00 48.35  ? 186 ALA C C   1 
ATOM   9410  O  O   . ALA C 2 186 ? 159.162 123.360 141.398 1.00 48.35  ? 186 ALA C O   1 
ATOM   9411  C  CB  . ALA C 2 186 ? 159.146 125.581 139.196 1.00 48.35  ? 186 ALA C CB  1 
ATOM   9412  N  N   . PHE C 2 187 ? 160.777 124.793 142.007 1.00 47.70  ? 187 PHE C N   1 
ATOM   9413  C  CA  . PHE C 2 187 ? 161.560 123.807 142.741 1.00 47.70  ? 187 PHE C CA  1 
ATOM   9414  C  C   . PHE C 2 187 ? 161.745 124.245 144.186 1.00 47.70  ? 187 PHE C C   1 
ATOM   9415  O  O   . PHE C 2 187 ? 162.851 124.214 144.731 1.00 47.70  ? 187 PHE C O   1 
ATOM   9416  C  CB  . PHE C 2 187 ? 162.914 123.579 142.076 1.00 47.70  ? 187 PHE C CB  1 
ATOM   9417  C  CG  . PHE C 2 187 ? 162.820 123.015 140.692 1.00 47.70  ? 187 PHE C CG  1 
ATOM   9418  C  CD1 . PHE C 2 187 ? 162.604 121.667 140.489 1.00 47.70  ? 187 PHE C CD1 1 
ATOM   9419  C  CD2 . PHE C 2 187 ? 162.947 123.838 139.591 1.00 47.70  ? 187 PHE C CD2 1 
ATOM   9420  C  CE1 . PHE C 2 187 ? 162.515 121.154 139.216 1.00 47.70  ? 187 PHE C CE1 1 
ATOM   9421  C  CE2 . PHE C 2 187 ? 162.859 123.329 138.320 1.00 47.70  ? 187 PHE C CE2 1 
ATOM   9422  C  CZ  . PHE C 2 187 ? 162.645 121.988 138.132 1.00 47.70  ? 187 PHE C CZ  1 
ATOM   9423  N  N   . TYR C 2 188 ? 160.653 124.660 144.825 1.00 54.12  ? 188 TYR C N   1 
ATOM   9424  C  CA  . TYR C 2 188 ? 160.751 125.262 146.147 1.00 54.12  ? 188 TYR C CA  1 
ATOM   9425  C  C   . TYR C 2 188 ? 160.500 124.245 147.251 1.00 54.12  ? 188 TYR C C   1 
ATOM   9426  O  O   . TYR C 2 188 ? 160.744 124.536 148.426 1.00 54.12  ? 188 TYR C O   1 
ATOM   9427  C  CB  . TYR C 2 188 ? 159.769 126.431 146.245 1.00 54.12  ? 188 TYR C CB  1 
ATOM   9428  C  CG  . TYR C 2 188 ? 159.930 127.311 147.461 1.00 54.12  ? 188 TYR C CG  1 
ATOM   9429  C  CD1 . TYR C 2 188 ? 160.988 128.202 147.556 1.00 54.12  ? 188 TYR C CD1 1 
ATOM   9430  C  CD2 . TYR C 2 188 ? 159.010 127.275 148.498 1.00 54.12  ? 188 TYR C CD2 1 
ATOM   9431  C  CE1 . TYR C 2 188 ? 161.136 129.020 148.654 1.00 54.12  ? 188 TYR C CE1 1 
ATOM   9432  C  CE2 . TYR C 2 188 ? 159.149 128.094 149.601 1.00 54.12  ? 188 TYR C CE2 1 
ATOM   9433  C  CZ  . TYR C 2 188 ? 160.219 128.960 149.675 1.00 54.12  ? 188 TYR C CZ  1 
ATOM   9434  O  OH  . TYR C 2 188 ? 160.364 129.774 150.773 1.00 54.12  ? 188 TYR C OH  1 
ATOM   9435  N  N   . THR C 2 189 ? 160.031 123.051 146.895 1.00 56.68  ? 189 THR C N   1 
ATOM   9436  C  CA  . THR C 2 189 ? 159.766 121.983 147.850 1.00 56.68  ? 189 THR C CA  1 
ATOM   9437  C  C   . THR C 2 189 ? 160.699 120.792 147.676 1.00 56.68  ? 189 THR C C   1 
ATOM   9438  O  O   . THR C 2 189 ? 161.090 120.167 148.665 1.00 56.68  ? 189 THR C O   1 
ATOM   9439  C  CB  . THR C 2 189 ? 158.311 121.521 147.721 1.00 56.68  ? 189 THR C CB  1 
ATOM   9440  O  OG1 . THR C 2 189 ? 157.437 122.627 147.972 1.00 56.68  ? 189 THR C OG1 1 
ATOM   9441  C  CG2 . THR C 2 189 ? 158.002 120.413 148.710 1.00 56.68  ? 189 THR C CG2 1 
ATOM   9442  N  N   . THR C 2 190 ? 161.075 120.472 146.443 1.00 54.97  ? 190 THR C N   1 
ATOM   9443  C  CA  . THR C 2 190 ? 161.962 119.347 146.197 1.00 54.97  ? 190 THR C CA  1 
ATOM   9444  C  C   . THR C 2 190 ? 163.401 119.696 146.563 1.00 54.97  ? 190 THR C C   1 
ATOM   9445  O  O   . THR C 2 190 ? 163.806 120.862 146.575 1.00 54.97  ? 190 THR C O   1 
ATOM   9446  C  CB  . THR C 2 190 ? 161.890 118.919 144.733 1.00 54.97  ? 190 THR C CB  1 
ATOM   9447  O  OG1 . THR C 2 190 ? 162.678 117.739 144.537 1.00 54.97  ? 190 THR C OG1 1 
ATOM   9448  C  CG2 . THR C 2 190 ? 162.402 120.022 143.829 1.00 54.97  ? 190 THR C CG2 1 
ATOM   9449  N  N   . ASP C 2 191 ? 164.181 118.658 146.864 1.00 54.83  ? 191 ASP C N   1 
ATOM   9450  C  CA  . ASP C 2 191 ? 165.584 118.815 147.219 1.00 54.83  ? 191 ASP C CA  1 
ATOM   9451  C  C   . ASP C 2 191 ? 166.534 118.212 146.195 1.00 54.83  ? 191 ASP C C   1 
ATOM   9452  O  O   . ASP C 2 191 ? 167.715 118.024 146.504 1.00 54.83  ? 191 ASP C O   1 
ATOM   9453  C  CB  . ASP C 2 191 ? 165.860 118.205 148.599 1.00 54.83  ? 191 ASP C CB  1 
ATOM   9454  C  CG  . ASP C 2 191 ? 165.581 116.714 148.653 1.00 54.83  ? 191 ASP C CG  1 
ATOM   9455  O  OD1 . ASP C 2 191 ? 165.100 116.147 147.651 1.00 54.83  ? 191 ASP C OD1 1 
ATOM   9456  O  OD2 . ASP C 2 191 ? 165.848 116.102 149.708 1.00 54.83  ? 191 ASP C OD2 1 
ATOM   9457  N  N   . ARG C 2 192 ? 166.054 117.892 144.993 1.00 48.38  ? 192 ARG C N   1 
ATOM   9458  C  CA  . ARG C 2 192 ? 166.949 117.418 143.947 1.00 48.38  ? 192 ARG C CA  1 
ATOM   9459  C  C   . ARG C 2 192 ? 167.597 118.566 143.193 1.00 48.38  ? 192 ARG C C   1 
ATOM   9460  O  O   . ARG C 2 192 ? 168.736 118.428 142.737 1.00 48.38  ? 192 ARG C O   1 
ATOM   9461  C  CB  . ARG C 2 192 ? 166.193 116.519 142.970 1.00 48.38  ? 192 ARG C CB  1 
ATOM   9462  C  CG  . ARG C 2 192 ? 165.677 115.237 143.591 1.00 48.38  ? 192 ARG C CG  1 
ATOM   9463  C  CD  . ARG C 2 192 ? 164.965 114.379 142.567 1.00 48.38  ? 192 ARG C CD  1 
ATOM   9464  N  NE  . ARG C 2 192 ? 165.894 113.865 141.567 1.00 48.38  ? 192 ARG C NE  1 
ATOM   9465  C  CZ  . ARG C 2 192 ? 165.524 113.233 140.459 1.00 48.38  ? 192 ARG C CZ  1 
ATOM   9466  N  NH1 . ARG C 2 192 ? 164.240 113.037 140.203 1.00 48.38  ? 192 ARG C NH1 1 
ATOM   9467  N  NH2 . ARG C 2 192 ? 166.440 112.799 139.605 1.00 48.38  ? 192 ARG C NH2 1 
ATOM   9468  N  N   . VAL C 2 193 ? 166.907 119.694 143.067 1.00 45.90  ? 193 VAL C N   1 
ATOM   9469  C  CA  . VAL C 2 193 ? 167.400 120.856 142.341 1.00 45.90  ? 193 VAL C CA  1 
ATOM   9470  C  C   . VAL C 2 193 ? 167.714 121.946 143.352 1.00 45.90  ? 193 VAL C C   1 
ATOM   9471  O  O   . VAL C 2 193 ? 166.893 122.239 144.228 1.00 45.90  ? 193 VAL C O   1 
ATOM   9472  C  CB  . VAL C 2 193 ? 166.372 121.349 141.310 1.00 45.90  ? 193 VAL C CB  1 
ATOM   9473  C  CG1 . VAL C 2 193 ? 166.906 122.559 140.571 1.00 45.90  ? 193 VAL C CG1 1 
ATOM   9474  C  CG2 . VAL C 2 193 ? 166.013 120.232 140.357 1.00 45.90  ? 193 VAL C CG2 1 
ATOM   9475  N  N   . MET C 2 194 ? 168.894 122.544 143.233 1.00 49.01  ? 194 MET C N   1 
ATOM   9476  C  CA  . MET C 2 194 ? 169.314 123.611 144.130 1.00 49.01  ? 194 MET C CA  1 
ATOM   9477  C  C   . MET C 2 194 ? 169.499 124.896 143.341 1.00 49.01  ? 194 MET C C   1 
ATOM   9478  O  O   . MET C 2 194 ? 170.313 124.947 142.415 1.00 49.01  ? 194 MET C O   1 
ATOM   9479  C  CB  . MET C 2 194 ? 170.607 123.245 144.851 1.00 49.01  ? 194 MET C CB  1 
ATOM   9480  C  CG  . MET C 2 194 ? 171.017 124.250 145.901 1.00 49.01  ? 194 MET C CG  1 
ATOM   9481  S  SD  . MET C 2 194 ? 172.443 123.698 146.838 1.00 49.01  ? 194 MET C SD  1 
ATOM   9482  C  CE  . MET C 2 194 ? 172.659 125.092 147.923 1.00 49.01  ? 194 MET C CE  1 
ATOM   9483  N  N   . THR C 2 195 ? 168.757 125.932 143.715 1.00 46.10  ? 195 THR C N   1 
ATOM   9484  C  CA  . THR C 2 195 ? 168.716 127.180 142.967 1.00 46.10  ? 195 THR C CA  1 
ATOM   9485  C  C   . THR C 2 195 ? 169.526 128.241 143.699 1.00 46.10  ? 195 THR C C   1 
ATOM   9486  O  O   . THR C 2 195 ? 169.060 128.808 144.693 1.00 46.10  ? 195 THR C O   1 
ATOM   9487  C  CB  . THR C 2 195 ? 167.275 127.645 142.770 1.00 46.10  ? 195 THR C CB  1 
ATOM   9488  O  OG1 . THR C 2 195 ? 166.679 127.896 144.046 1.00 46.10  ? 195 THR C OG1 1 
ATOM   9489  C  CG2 . THR C 2 195 ? 166.474 126.576 142.054 1.00 46.10  ? 195 THR C CG2 1 
ATOM   9490  N  N   . VAL C 2 196 ? 170.734 128.502 143.207 1.00 44.40  ? 196 VAL C N   1 
ATOM   9491  C  CA  . VAL C 2 196 ? 171.582 129.584 143.692 1.00 44.40  ? 196 VAL C CA  1 
ATOM   9492  C  C   . VAL C 2 196 ? 171.343 130.792 142.797 1.00 44.40  ? 196 VAL C C   1 
ATOM   9493  O  O   . VAL C 2 196 ? 171.478 130.701 141.572 1.00 44.40  ? 196 VAL C O   1 
ATOM   9494  C  CB  . VAL C 2 196 ? 173.063 129.180 143.690 1.00 44.40  ? 196 VAL C CB  1 
ATOM   9495  C  CG1 . VAL C 2 196 ? 173.932 130.349 144.108 1.00 44.40  ? 196 VAL C CG1 1 
ATOM   9496  C  CG2 . VAL C 2 196 ? 173.288 127.989 144.602 1.00 44.40  ? 196 VAL C CG2 1 
ATOM   9497  N  N   . SER C 2 197 ? 170.992 131.925 143.399 1.00 44.23  ? 197 SER C N   1 
ATOM   9498  C  CA  . SER C 2 197 ? 170.586 133.105 142.649 1.00 44.23  ? 197 SER C CA  1 
ATOM   9499  C  C   . SER C 2 197 ? 171.227 134.345 143.246 1.00 44.23  ? 197 SER C C   1 
ATOM   9500  O  O   . SER C 2 197 ? 170.925 134.710 144.385 1.00 44.23  ? 197 SER C O   1 
ATOM   9501  C  CB  . SER C 2 197 ? 169.063 133.252 142.655 1.00 44.23  ? 197 SER C CB  1 
ATOM   9502  O  OG  . SER C 2 197 ? 168.662 134.421 141.967 1.00 44.23  ? 197 SER C OG  1 
ATOM   9503  N  N   . PHE C 2 198 ? 172.096 135.001 142.479 1.00 49.72  ? 198 PHE C N   1 
ATOM   9504  C  CA  . PHE C 2 198 ? 172.681 136.272 142.887 1.00 49.72  ? 198 PHE C CA  1 
ATOM   9505  C  C   . PHE C 2 198 ? 171.882 137.396 142.247 1.00 49.72  ? 198 PHE C C   1 
ATOM   9506  O  O   . PHE C 2 198 ? 171.775 137.455 141.018 1.00 49.72  ? 198 PHE C O   1 
ATOM   9507  C  CB  . PHE C 2 198 ? 174.151 136.390 142.473 1.00 49.72  ? 198 PHE C CB  1 
ATOM   9508  C  CG  . PHE C 2 198 ? 175.070 135.419 143.162 1.00 49.72  ? 198 PHE C CG  1 
ATOM   9509  C  CD1 . PHE C 2 198 ? 174.600 134.544 144.120 1.00 49.72  ? 198 PHE C CD1 1 
ATOM   9510  C  CD2 . PHE C 2 198 ? 176.423 135.431 142.895 1.00 49.72  ? 198 PHE C CD2 1 
ATOM   9511  C  CE1 . PHE C 2 198 ? 175.450 133.667 144.763 1.00 49.72  ? 198 PHE C CE1 1 
ATOM   9512  C  CE2 . PHE C 2 198 ? 177.276 134.562 143.543 1.00 49.72  ? 198 PHE C CE2 1 
ATOM   9513  C  CZ  . PHE C 2 198 ? 176.786 133.678 144.474 1.00 49.72  ? 198 PHE C CZ  1 
ATOM   9514  N  N   . HIS C 2 199 ? 171.323 138.287 143.064 1.00 47.30  ? 199 HIS C N   1 
ATOM   9515  C  CA  . HIS C 2 199 ? 170.452 139.298 142.480 1.00 47.30  ? 199 HIS C CA  1 
ATOM   9516  C  C   . HIS C 2 199 ? 170.589 140.623 143.212 1.00 47.30  ? 199 HIS C C   1 
ATOM   9517  O  O   . HIS C 2 199 ? 171.569 140.871 143.917 1.00 47.30  ? 199 HIS C O   1 
ATOM   9518  C  CB  . HIS C 2 199 ? 168.991 138.838 142.468 1.00 47.30  ? 199 HIS C CB  1 
ATOM   9519  C  CG  . HIS C 2 199 ? 168.436 138.532 143.822 1.00 47.30  ? 199 HIS C CG  1 
ATOM   9520  N  ND1 . HIS C 2 199 ? 168.638 137.325 144.452 1.00 47.30  ? 199 HIS C ND1 1 
ATOM   9521  C  CD2 . HIS C 2 199 ? 167.670 139.270 144.658 1.00 47.30  ? 199 HIS C CD2 1 
ATOM   9522  C  CE1 . HIS C 2 199 ? 168.025 137.334 145.622 1.00 47.30  ? 199 HIS C CE1 1 
ATOM   9523  N  NE2 . HIS C 2 199 ? 167.431 138.503 145.771 1.00 47.30  ? 199 HIS C NE2 1 
ATOM   9524  N  N   . LYS C 2 200 ? 169.602 141.487 142.996 1.00 47.83  ? 200 LYS C N   1 
ATOM   9525  C  CA  . LYS C 2 200 ? 169.567 142.816 143.594 1.00 47.83  ? 200 LYS C CA  1 
ATOM   9526  C  C   . LYS C 2 200 ? 168.260 142.967 144.360 1.00 47.83  ? 200 LYS C C   1 
ATOM   9527  O  O   . LYS C 2 200 ? 167.185 143.029 143.756 1.00 47.83  ? 200 LYS C O   1 
ATOM   9528  C  CB  . LYS C 2 200 ? 169.699 143.891 142.515 1.00 47.83  ? 200 LYS C CB  1 
ATOM   9529  C  CG  . LYS C 2 200 ? 169.828 145.321 143.023 1.00 47.83  ? 200 LYS C CG  1 
ATOM   9530  C  CD  . LYS C 2 200 ? 168.482 146.028 143.040 1.00 47.83  ? 200 LYS C CD  1 
ATOM   9531  C  CE  . LYS C 2 200 ? 168.612 147.515 143.339 1.00 47.83  ? 200 LYS C CE  1 
ATOM   9532  N  NZ  . LYS C 2 200 ? 169.077 147.783 144.722 1.00 47.83  ? 200 LYS C NZ  1 
ATOM   9533  N  N   . TYR C 2 201 ? 168.352 143.027 145.687 1.00 50.76  ? 201 TYR C N   1 
ATOM   9534  C  CA  . TYR C 2 201 ? 167.157 143.050 146.526 1.00 50.76  ? 201 TYR C CA  1 
ATOM   9535  C  C   . TYR C 2 201 ? 167.121 144.381 147.270 1.00 50.76  ? 201 TYR C C   1 
ATOM   9536  O  O   . TYR C 2 201 ? 167.902 144.601 148.199 1.00 50.76  ? 201 TYR C O   1 
ATOM   9537  C  CB  . TYR C 2 201 ? 167.143 141.876 147.493 1.00 50.76  ? 201 TYR C CB  1 
ATOM   9538  C  CG  . TYR C 2 201 ? 165.914 141.816 148.363 1.00 50.76  ? 201 TYR C CG  1 
ATOM   9539  C  CD1 . TYR C 2 201 ? 164.713 141.344 147.864 1.00 50.76  ? 201 TYR C CD1 1 
ATOM   9540  C  CD2 . TYR C 2 201 ? 165.953 142.240 149.681 1.00 50.76  ? 201 TYR C CD2 1 
ATOM   9541  C  CE1 . TYR C 2 201 ? 163.585 141.288 148.656 1.00 50.76  ? 201 TYR C CE1 1 
ATOM   9542  C  CE2 . TYR C 2 201 ? 164.829 142.190 150.478 1.00 50.76  ? 201 TYR C CE2 1 
ATOM   9543  C  CZ  . TYR C 2 201 ? 163.648 141.713 149.959 1.00 50.76  ? 201 TYR C CZ  1 
ATOM   9544  O  OH  . TYR C 2 201 ? 162.522 141.657 150.744 1.00 50.76  ? 201 TYR C OH  1 
ATOM   9545  N  N   . GLY C 2 202 ? 166.221 145.257 146.844 1.00 53.37  ? 202 GLY C N   1 
ATOM   9546  C  CA  . GLY C 2 202 ? 165.858 146.440 147.596 1.00 53.37  ? 202 GLY C CA  1 
ATOM   9547  C  C   . GLY C 2 202 ? 164.367 146.626 147.450 1.00 53.37  ? 202 GLY C C   1 
ATOM   9548  O  O   . GLY C 2 202 ? 163.581 145.855 148.007 1.00 53.37  ? 202 GLY C O   1 
ATOM   9549  N  N   . GLU C 2 203 ? 163.962 147.640 146.694 1.00 54.91  ? 203 GLU C N   1 
ATOM   9550  C  CA  . GLU C 2 203 ? 162.627 147.622 146.118 1.00 54.91  ? 203 GLU C CA  1 
ATOM   9551  C  C   . GLU C 2 203 ? 162.670 147.436 144.612 1.00 54.91  ? 203 GLU C C   1 
ATOM   9552  O  O   . GLU C 2 203 ? 162.895 148.419 143.902 1.00 54.91  ? 203 GLU C O   1 
ATOM   9553  C  CB  . GLU C 2 203 ? 161.856 148.903 146.456 1.00 54.91  ? 203 GLU C CB  1 
ATOM   9554  C  CG  . GLU C 2 203 ? 160.359 148.753 146.280 1.00 54.91  ? 203 GLU C CG  1 
ATOM   9555  C  CD  . GLU C 2 203 ? 159.916 148.942 144.852 1.00 54.91  ? 203 GLU C CD  1 
ATOM   9556  O  OE1 . GLU C 2 203 ? 160.564 149.727 144.134 1.00 54.91  ? 203 GLU C OE1 1 
ATOM   9557  O  OE2 . GLU C 2 203 ? 158.932 148.293 144.443 1.00 54.91  ? 203 GLU C OE2 1 
ATOM   9558  N  N   . TYR C 2 204 ? 162.486 146.226 144.097 1.00 48.43  ? 204 TYR C N   1 
ATOM   9559  C  CA  . TYR C 2 204 ? 162.923 145.937 142.744 1.00 48.43  ? 204 TYR C CA  1 
ATOM   9560  C  C   . TYR C 2 204 ? 162.213 144.687 142.232 1.00 48.43  ? 204 TYR C C   1 
ATOM   9561  O  O   . TYR C 2 204 ? 161.733 143.856 143.004 1.00 48.43  ? 204 TYR C O   1 
ATOM   9562  C  CB  . TYR C 2 204 ? 164.442 145.760 142.745 1.00 48.43  ? 204 TYR C CB  1 
ATOM   9563  C  CG  . TYR C 2 204 ? 165.121 145.751 141.401 1.00 48.43  ? 204 TYR C CG  1 
ATOM   9564  C  CD1 . TYR C 2 204 ? 165.340 146.930 140.708 1.00 48.43  ? 204 TYR C CD1 1 
ATOM   9565  C  CD2 . TYR C 2 204 ? 165.581 144.571 140.844 1.00 48.43  ? 204 TYR C CD2 1 
ATOM   9566  C  CE1 . TYR C 2 204 ? 165.975 146.932 139.489 1.00 48.43  ? 204 TYR C CE1 1 
ATOM   9567  C  CE2 . TYR C 2 204 ? 166.216 144.565 139.626 1.00 48.43  ? 204 TYR C CE2 1 
ATOM   9568  C  CZ  . TYR C 2 204 ? 166.409 145.747 138.953 1.00 48.43  ? 204 TYR C CZ  1 
ATOM   9569  O  OH  . TYR C 2 204 ? 167.042 145.744 137.736 1.00 48.43  ? 204 TYR C OH  1 
ATOM   9570  N  N   . PHE C 2 205 ? 162.135 144.562 140.914 1.00 47.37  ? 205 PHE C N   1 
ATOM   9571  C  CA  . PHE C 2 205 ? 161.413 143.439 140.335 1.00 47.37  ? 205 PHE C CA  1 
ATOM   9572  C  C   . PHE C 2 205 ? 162.162 142.138 140.618 1.00 47.37  ? 205 PHE C C   1 
ATOM   9573  O  O   . PHE C 2 205 ? 163.396 142.107 140.555 1.00 47.37  ? 205 PHE C O   1 
ATOM   9574  C  CB  . PHE C 2 205 ? 161.254 143.629 138.829 1.00 47.37  ? 205 PHE C CB  1 
ATOM   9575  C  CG  . PHE C 2 205 ? 160.319 142.646 138.192 1.00 47.37  ? 205 PHE C CG  1 
ATOM   9576  C  CD1 . PHE C 2 205 ? 158.952 142.861 138.212 1.00 47.37  ? 205 PHE C CD1 1 
ATOM   9577  C  CD2 . PHE C 2 205 ? 160.799 141.497 137.597 1.00 47.37  ? 205 PHE C CD2 1 
ATOM   9578  C  CE1 . PHE C 2 205 ? 158.087 141.959 137.630 1.00 47.37  ? 205 PHE C CE1 1 
ATOM   9579  C  CE2 . PHE C 2 205 ? 159.936 140.595 137.016 1.00 47.37  ? 205 PHE C CE2 1 
ATOM   9580  C  CZ  . PHE C 2 205 ? 158.579 140.826 137.033 1.00 47.37  ? 205 PHE C CZ  1 
ATOM   9581  N  N   . PRO C 2 206 ? 161.455 141.037 140.929 1.00 47.58  ? 206 PRO C N   1 
ATOM   9582  C  CA  . PRO C 2 206 ? 160.002 140.919 141.082 1.00 47.58  ? 206 PRO C CA  1 
ATOM   9583  C  C   . PRO C 2 206 ? 159.520 141.211 142.502 1.00 47.58  ? 206 PRO C C   1 
ATOM   9584  O  O   . PRO C 2 206 ? 158.323 141.136 142.775 1.00 47.58  ? 206 PRO C O   1 
ATOM   9585  C  CB  . PRO C 2 206 ? 159.741 139.459 140.722 1.00 47.58  ? 206 PRO C CB  1 
ATOM   9586  C  CG  . PRO C 2 206 ? 160.970 138.766 141.153 1.00 47.58  ? 206 PRO C CG  1 
ATOM   9587  C  CD  . PRO C 2 206 ? 162.108 139.717 140.929 1.00 47.58  ? 206 PRO C CD  1 
ATOM   9588  N  N   . GLY C 2 207 ? 160.453 141.539 143.392 1.00 50.69  ? 207 GLY C N   1 
ATOM   9589  C  CA  . GLY C 2 207 ? 160.117 141.764 144.782 1.00 50.69  ? 207 GLY C CA  1 
ATOM   9590  C  C   . GLY C 2 207 ? 160.469 140.622 145.701 1.00 50.69  ? 207 GLY C C   1 
ATOM   9591  O  O   . GLY C 2 207 ? 161.002 140.857 146.789 1.00 50.69  ? 207 GLY C O   1 
ATOM   9592  N  N   . THR C 2 208 ? 160.196 139.384 145.295 1.00 52.57  ? 208 THR C N   1 
ATOM   9593  C  CA  . THR C 2 208 ? 160.550 138.224 146.100 1.00 52.57  ? 208 THR C CA  1 
ATOM   9594  C  C   . THR C 2 208 ? 162.054 137.991 146.063 1.00 52.57  ? 208 THR C C   1 
ATOM   9595  O  O   . THR C 2 208 ? 162.770 138.642 145.296 1.00 52.57  ? 208 THR C O   1 
ATOM   9596  C  CB  . THR C 2 208 ? 159.809 136.981 145.609 1.00 52.57  ? 208 THR C CB  1 
ATOM   9597  O  OG1 . THR C 2 208 ? 160.163 136.723 144.246 1.00 52.57  ? 208 THR C OG1 1 
ATOM   9598  C  CG2 . THR C 2 208 ? 158.310 137.185 145.704 1.00 52.57  ? 208 THR C CG2 1 
ATOM   9599  N  N   . GLY C 2 209 ? 162.542 137.074 146.889 1.00 53.33  ? 209 GLY C N   1 
ATOM   9600  C  CA  . GLY C 2 209 ? 163.959 136.772 146.900 1.00 53.33  ? 209 GLY C CA  1 
ATOM   9601  C  C   . GLY C 2 209 ? 164.703 137.290 148.108 1.00 53.33  ? 209 GLY C C   1 
ATOM   9602  O  O   . GLY C 2 209 ? 165.812 137.820 147.969 1.00 53.33  ? 209 GLY C O   1 
ATOM   9603  N  N   . ASP C 2 210 ? 164.127 137.148 149.295 1.00 57.39  ? 210 ASP C N   1 
ATOM   9604  C  CA  . ASP C 2 210 ? 164.767 137.635 150.504 1.00 57.39  ? 210 ASP C CA  1 
ATOM   9605  C  C   . ASP C 2 210 ? 165.896 136.689 150.909 1.00 57.39  ? 210 ASP C C   1 
ATOM   9606  O  O   . ASP C 2 210 ? 166.200 135.713 150.221 1.00 57.39  ? 210 ASP C O   1 
ATOM   9607  C  CB  . ASP C 2 210 ? 163.728 137.774 151.621 1.00 57.39  ? 210 ASP C CB  1 
ATOM   9608  C  CG  . ASP C 2 210 ? 164.226 138.593 152.793 1.00 57.39  ? 210 ASP C CG  1 
ATOM   9609  O  OD1 . ASP C 2 210 ? 165.402 139.006 152.769 1.00 57.39  ? 210 ASP C OD1 1 
ATOM   9610  O  OD2 . ASP C 2 210 ? 163.440 138.826 153.734 1.00 57.39  ? 210 ASP C OD2 1 
ATOM   9611  N  N   . LEU C 2 211 ? 166.534 136.996 152.038 1.00 58.12  ? 211 LEU C N   1 
ATOM   9612  C  CA  . LEU C 2 211 ? 167.571 136.113 152.556 1.00 58.12  ? 211 LEU C CA  1 
ATOM   9613  C  C   . LEU C 2 211 ? 166.982 135.031 153.453 1.00 58.12  ? 211 LEU C C   1 
ATOM   9614  O  O   . LEU C 2 211 ? 167.666 134.057 153.783 1.00 58.12  ? 211 LEU C O   1 
ATOM   9615  C  CB  . LEU C 2 211 ? 168.613 136.930 153.320 1.00 58.12  ? 211 LEU C CB  1 
ATOM   9616  C  CG  . LEU C 2 211 ? 169.862 136.213 153.829 1.00 58.12  ? 211 LEU C CG  1 
ATOM   9617  C  CD1 . LEU C 2 211 ? 170.687 135.717 152.664 1.00 58.12  ? 211 LEU C CD1 1 
ATOM   9618  C  CD2 . LEU C 2 211 ? 170.685 137.113 154.726 1.00 58.12  ? 211 LEU C CD2 1 
ATOM   9619  N  N   . ARG C 2 212 ? 165.712 135.172 153.837 1.00 63.23  ? 212 ARG C N   1 
ATOM   9620  C  CA  . ARG C 2 212 ? 165.148 134.294 154.855 1.00 63.23  ? 212 ARG C CA  1 
ATOM   9621  C  C   . ARG C 2 212 ? 164.282 133.201 154.241 1.00 63.23  ? 212 ARG C C   1 
ATOM   9622  O  O   . ARG C 2 212 ? 164.162 132.109 154.807 1.00 63.23  ? 212 ARG C O   1 
ATOM   9623  C  CB  . ARG C 2 212 ? 164.347 135.120 155.858 1.00 63.23  ? 212 ARG C CB  1 
ATOM   9624  C  CG  . ARG C 2 212 ? 165.211 136.054 156.679 1.00 63.23  ? 212 ARG C CG  1 
ATOM   9625  C  CD  . ARG C 2 212 ? 164.387 136.910 157.616 1.00 63.23  ? 212 ARG C CD  1 
ATOM   9626  N  NE  . ARG C 2 212 ? 165.244 137.770 158.423 1.00 63.23  ? 212 ARG C NE  1 
ATOM   9627  C  CZ  . ARG C 2 212 ? 165.634 138.986 158.058 1.00 63.23  ? 212 ARG C CZ  1 
ATOM   9628  N  NH1 . ARG C 2 212 ? 165.243 139.490 156.897 1.00 63.23  ? 212 ARG C NH1 1 
ATOM   9629  N  NH2 . ARG C 2 212 ? 166.418 139.698 158.855 1.00 63.23  ? 212 ARG C NH2 1 
ATOM   9630  N  N   . ASP C 2 213 ? 163.664 133.471 153.095 1.00 60.79  ? 213 ASP C N   1 
ATOM   9631  C  CA  . ASP C 2 213 ? 162.868 132.453 152.424 1.00 60.79  ? 213 ASP C CA  1 
ATOM   9632  C  C   . ASP C 2 213 ? 163.780 131.438 151.742 1.00 60.79  ? 213 ASP C C   1 
ATOM   9633  O  O   . ASP C 2 213 ? 164.428 131.739 150.735 1.00 60.79  ? 213 ASP C O   1 
ATOM   9634  C  CB  . ASP C 2 213 ? 161.897 133.094 151.430 1.00 60.79  ? 213 ASP C CB  1 
ATOM   9635  C  CG  . ASP C 2 213 ? 162.578 134.037 150.461 1.00 60.79  ? 213 ASP C CG  1 
ATOM   9636  O  OD1 . ASP C 2 213 ? 163.789 134.289 150.622 1.00 60.79  ? 213 ASP C OD1 1 
ATOM   9637  O  OD2 . ASP C 2 213 ? 161.899 134.528 149.534 1.00 60.79  ? 213 ASP C OD2 1 
ATOM   9638  N  N   . ILE C 2 214 ? 163.835 130.232 152.305 1.00 60.38  ? 214 ILE C N   1 
ATOM   9639  C  CA  . ILE C 2 214 ? 164.748 129.198 151.832 1.00 60.38  ? 214 ILE C CA  1 
ATOM   9640  C  C   . ILE C 2 214 ? 163.954 128.068 151.192 1.00 60.38  ? 214 ILE C C   1 
ATOM   9641  O  O   . ILE C 2 214 ? 163.689 128.086 149.986 1.00 60.38  ? 214 ILE C O   1 
ATOM   9642  C  CB  . ILE C 2 214 ? 165.629 128.675 152.980 1.00 60.38  ? 214 ILE C CB  1 
ATOM   9643  C  CG1 . ILE C 2 214 ? 166.359 129.833 153.647 1.00 60.38  ? 214 ILE C CG1 1 
ATOM   9644  C  CG2 . ILE C 2 214 ? 166.663 127.730 152.448 1.00 60.38  ? 214 ILE C CG2 1 
ATOM   9645  C  CD1 . ILE C 2 214 ? 167.275 130.583 152.705 1.00 60.38  ? 214 ILE C CD1 1 
ATOM   9646  N  N   . GLY C 2 215 ? 163.572 127.081 151.988 1.00 61.36  ? 215 GLY C N   1 
ATOM   9647  C  CA  . GLY C 2 215 ? 162.807 125.967 151.469 1.00 61.36  ? 215 GLY C CA  1 
ATOM   9648  C  C   . GLY C 2 215 ? 161.625 125.679 152.362 1.00 61.36  ? 215 GLY C C   1 
ATOM   9649  O  O   . GLY C 2 215 ? 161.661 125.890 153.577 1.00 61.36  ? 215 GLY C O   1 
ATOM   9650  N  N   . ALA C 2 216 ? 160.562 125.188 151.731 1.00 61.06  ? 216 ALA C N   1 
ATOM   9651  C  CA  . ALA C 2 216 ? 159.338 124.847 152.436 1.00 61.06  ? 216 ALA C CA  1 
ATOM   9652  C  C   . ALA C 2 216 ? 159.001 123.389 152.179 1.00 61.06  ? 216 ALA C C   1 
ATOM   9653  O  O   . ALA C 2 216 ? 158.453 123.047 151.128 1.00 61.06  ? 216 ALA C O   1 
ATOM   9654  C  CB  . ALA C 2 216 ? 158.169 125.735 152.002 1.00 61.06  ? 216 ALA C CB  1 
ATOM   9655  N  N   . GLY C 2 217 ? 159.333 122.535 153.143 1.00 63.17  ? 217 GLY C N   1 
ATOM   9656  C  CA  . GLY C 2 217 ? 159.024 121.124 153.004 1.00 63.17  ? 217 GLY C CA  1 
ATOM   9657  C  C   . GLY C 2 217 ? 160.279 120.275 153.037 1.00 63.17  ? 217 GLY C C   1 
ATOM   9658  O  O   . GLY C 2 217 ? 161.156 120.441 153.892 1.00 63.17  ? 217 GLY C O   1 
ATOM   9659  N  N   . LYS C 2 218 ? 160.366 119.346 152.085 1.00 63.14  ? 218 LYS C N   1 
ATOM   9660  C  CA  . LYS C 2 218 ? 161.525 118.465 152.017 1.00 63.14  ? 218 LYS C CA  1 
ATOM   9661  C  C   . LYS C 2 218 ? 162.773 119.226 151.594 1.00 63.14  ? 218 LYS C C   1 
ATOM   9662  O  O   . LYS C 2 218 ? 163.880 118.926 152.056 1.00 63.14  ? 218 LYS C O   1 
ATOM   9663  C  CB  . LYS C 2 218 ? 161.249 117.316 151.050 1.00 63.14  ? 218 LYS C CB  1 
ATOM   9664  C  CG  . LYS C 2 218 ? 162.386 116.320 150.932 1.00 63.14  ? 218 LYS C CG  1 
ATOM   9665  C  CD  . LYS C 2 218 ? 162.018 115.168 150.015 1.00 63.14  ? 218 LYS C CD  1 
ATOM   9666  C  CE  . LYS C 2 218 ? 162.012 115.611 148.562 1.00 63.14  ? 218 LYS C CE  1 
ATOM   9667  N  NZ  . LYS C 2 218 ? 161.784 114.479 147.623 1.00 63.14  ? 218 LYS C NZ  1 
ATOM   9668  N  N   . GLY C 2 219 ? 162.615 120.217 150.721 1.00 60.39  ? 219 GLY C N   1 
ATOM   9669  C  CA  . GLY C 2 219 ? 163.751 120.912 150.153 1.00 60.39  ? 219 GLY C CA  1 
ATOM   9670  C  C   . GLY C 2 219 ? 164.168 122.154 150.908 1.00 60.39  ? 219 GLY C C   1 
ATOM   9671  O  O   . GLY C 2 219 ? 164.560 123.152 150.297 1.00 60.39  ? 219 GLY C O   1 
ATOM   9672  N  N   . LYS C 2 220 ? 164.087 122.113 152.232 1.00 63.14  ? 220 LYS C N   1 
ATOM   9673  C  CA  . LYS C 2 220 ? 164.600 123.212 153.031 1.00 63.14  ? 220 LYS C CA  1 
ATOM   9674  C  C   . LYS C 2 220 ? 166.123 123.219 152.974 1.00 63.14  ? 220 LYS C C   1 
ATOM   9675  O  O   . LYS C 2 220 ? 166.763 122.174 152.837 1.00 63.14  ? 220 LYS C O   1 
ATOM   9676  C  CB  . LYS C 2 220 ? 164.115 123.098 154.476 1.00 63.14  ? 220 LYS C CB  1 
ATOM   9677  C  CG  . LYS C 2 220 ? 164.463 124.292 155.343 1.00 63.14  ? 220 LYS C CG  1 
ATOM   9678  C  CD  . LYS C 2 220 ? 163.872 124.164 156.732 1.00 63.14  ? 220 LYS C CD  1 
ATOM   9679  C  CE  . LYS C 2 220 ? 164.224 125.370 157.585 1.00 63.14  ? 220 LYS C CE  1 
ATOM   9680  N  NZ  . LYS C 2 220 ? 163.655 125.269 158.956 1.00 63.14  ? 220 LYS C NZ  1 
ATOM   9681  N  N   . TYR C 2 221 ? 166.697 124.421 153.053 1.00 63.25  ? 221 TYR C N   1 
ATOM   9682  C  CA  . TYR C 2 221 ? 168.136 124.662 152.945 1.00 63.25  ? 221 TYR C CA  1 
ATOM   9683  C  C   . TYR C 2 221 ? 168.660 124.412 151.535 1.00 63.25  ? 221 TYR C C   1 
ATOM   9684  O  O   . TYR C 2 221 ? 169.867 124.501 151.296 1.00 63.25  ? 221 TYR C O   1 
ATOM   9685  C  CB  . TYR C 2 221 ? 168.928 123.835 153.965 1.00 63.25  ? 221 TYR C CB  1 
ATOM   9686  C  CG  . TYR C 2 221 ? 168.696 124.250 155.400 1.00 63.25  ? 221 TYR C CG  1 
ATOM   9687  C  CD1 . TYR C 2 221 ? 168.115 125.473 155.705 1.00 63.25  ? 221 TYR C CD1 1 
ATOM   9688  C  CD2 . TYR C 2 221 ? 169.050 123.417 156.448 1.00 63.25  ? 221 TYR C CD2 1 
ATOM   9689  C  CE1 . TYR C 2 221 ? 167.899 125.854 157.012 1.00 63.25  ? 221 TYR C CE1 1 
ATOM   9690  C  CE2 . TYR C 2 221 ? 168.837 123.790 157.757 1.00 63.25  ? 221 TYR C CE2 1 
ATOM   9691  C  CZ  . TYR C 2 221 ? 168.262 125.009 158.034 1.00 63.25  ? 221 TYR C CZ  1 
ATOM   9692  O  OH  . TYR C 2 221 ? 168.048 125.385 159.339 1.00 63.25  ? 221 TYR C OH  1 
ATOM   9693  N  N   . TYR C 2 222 ? 167.769 124.121 150.588 1.00 60.50  ? 222 TYR C N   1 
ATOM   9694  C  CA  . TYR C 2 222 ? 168.112 123.898 149.188 1.00 60.50  ? 222 TYR C CA  1 
ATOM   9695  C  C   . TYR C 2 222 ? 167.606 125.032 148.304 1.00 60.50  ? 222 TYR C C   1 
ATOM   9696  O  O   . TYR C 2 222 ? 166.915 124.804 147.309 1.00 60.50  ? 222 TYR C O   1 
ATOM   9697  C  CB  . TYR C 2 222 ? 167.560 122.563 148.690 1.00 60.50  ? 222 TYR C CB  1 
ATOM   9698  C  CG  . TYR C 2 222 ? 168.289 121.341 149.198 1.00 60.50  ? 222 TYR C CG  1 
ATOM   9699  C  CD1 . TYR C 2 222 ? 169.457 120.909 148.591 1.00 60.50  ? 222 TYR C CD1 1 
ATOM   9700  C  CD2 . TYR C 2 222 ? 167.807 120.615 150.275 1.00 60.50  ? 222 TYR C CD2 1 
ATOM   9701  C  CE1 . TYR C 2 222 ? 170.126 119.793 149.044 1.00 60.50  ? 222 TYR C CE1 1 
ATOM   9702  C  CE2 . TYR C 2 222 ? 168.470 119.495 150.735 1.00 60.50  ? 222 TYR C CE2 1 
ATOM   9703  C  CZ  . TYR C 2 222 ? 169.630 119.089 150.116 1.00 60.50  ? 222 TYR C CZ  1 
ATOM   9704  O  OH  . TYR C 2 222 ? 170.299 117.975 150.567 1.00 60.50  ? 222 TYR C OH  1 
ATOM   9705  N  N   . ALA C 2 223 ? 167.947 126.270 148.657 1.00 51.66  ? 223 ALA C N   1 
ATOM   9706  C  CA  . ALA C 2 223 ? 167.595 127.427 147.836 1.00 51.66  ? 223 ALA C CA  1 
ATOM   9707  C  C   . ALA C 2 223 ? 168.427 128.605 148.319 1.00 51.66  ? 223 ALA C C   1 
ATOM   9708  O  O   . ALA C 2 223 ? 168.113 129.198 149.354 1.00 51.66  ? 223 ALA C O   1 
ATOM   9709  C  CB  . ALA C 2 223 ? 166.106 127.732 147.923 1.00 51.66  ? 223 ALA C CB  1 
ATOM   9710  N  N   . VAL C 2 224 ? 169.476 128.940 147.576 1.00 45.85  ? 224 VAL C N   1 
ATOM   9711  C  CA  . VAL C 2 224 ? 170.382 130.025 147.932 1.00 45.85  ? 224 VAL C CA  1 
ATOM   9712  C  C   . VAL C 2 224 ? 169.936 131.300 147.234 1.00 45.85  ? 224 VAL C C   1 
ATOM   9713  O  O   . VAL C 2 224 ? 169.834 131.344 146.001 1.00 45.85  ? 224 VAL C O   1 
ATOM   9714  C  CB  . VAL C 2 224 ? 171.834 129.677 147.569 1.00 45.85  ? 224 VAL C CB  1 
ATOM   9715  C  CG1 . VAL C 2 224 ? 172.709 130.905 147.651 1.00 45.85  ? 224 VAL C CG1 1 
ATOM   9716  C  CG2 . VAL C 2 224 ? 172.352 128.610 148.505 1.00 45.85  ? 224 VAL C CG2 1 
ATOM   9717  N  N   . ASN C 2 225 ? 169.661 132.335 148.025 1.00 47.19  ? 225 ASN C N   1 
ATOM   9718  C  CA  . ASN C 2 225 ? 169.375 133.673 147.530 1.00 47.19  ? 225 ASN C CA  1 
ATOM   9719  C  C   . ASN C 2 225 ? 170.424 134.619 148.090 1.00 47.19  ? 225 ASN C C   1 
ATOM   9720  O  O   . ASN C 2 225 ? 170.548 134.754 149.311 1.00 47.19  ? 225 ASN C O   1 
ATOM   9721  C  CB  . ASN C 2 225 ? 167.982 134.141 147.951 1.00 47.19  ? 225 ASN C CB  1 
ATOM   9722  C  CG  . ASN C 2 225 ? 166.886 133.242 147.438 1.00 47.19  ? 225 ASN C CG  1 
ATOM   9723  O  OD1 . ASN C 2 225 ? 166.179 132.608 148.217 1.00 47.19  ? 225 ASN C OD1 1 
ATOM   9724  N  ND2 . ASN C 2 225 ? 166.737 133.177 146.123 1.00 47.19  ? 225 ASN C ND2 1 
ATOM   9725  N  N   . TYR C 2 226 ? 171.183 135.266 147.205 1.00 50.15  ? 226 TYR C N   1 
ATOM   9726  C  CA  . TYR C 2 226 ? 172.223 136.210 147.604 1.00 50.15  ? 226 TYR C CA  1 
ATOM   9727  C  C   . TYR C 2 226 ? 171.761 137.599 147.178 1.00 50.15  ? 226 TYR C C   1 
ATOM   9728  O  O   . TYR C 2 226 ? 171.882 137.979 145.999 1.00 50.15  ? 226 TYR C O   1 
ATOM   9729  C  CB  . TYR C 2 226 ? 173.573 135.859 146.990 1.00 50.15  ? 226 TYR C CB  1 
ATOM   9730  C  CG  . TYR C 2 226 ? 174.741 136.530 147.665 1.00 50.15  ? 226 TYR C CG  1 
ATOM   9731  C  CD1 . TYR C 2 226 ? 175.309 135.985 148.806 1.00 50.15  ? 226 TYR C CD1 1 
ATOM   9732  C  CD2 . TYR C 2 226 ? 175.256 137.721 147.187 1.00 50.15  ? 226 TYR C CD2 1 
ATOM   9733  C  CE1 . TYR C 2 226 ? 176.372 136.589 149.431 1.00 50.15  ? 226 TYR C CE1 1 
ATOM   9734  C  CE2 . TYR C 2 226 ? 176.317 138.336 147.813 1.00 50.15  ? 226 TYR C CE2 1 
ATOM   9735  C  CZ  . TYR C 2 226 ? 176.870 137.767 148.934 1.00 50.15  ? 226 TYR C CZ  1 
ATOM   9736  O  OH  . TYR C 2 226 ? 177.928 138.383 149.556 1.00 50.15  ? 226 TYR C OH  1 
ATOM   9737  N  N   . PRO C 2 227 ? 171.195 138.370 148.105 1.00 49.59  ? 227 PRO C N   1 
ATOM   9738  C  CA  . PRO C 2 227 ? 170.705 139.709 147.761 1.00 49.59  ? 227 PRO C CA  1 
ATOM   9739  C  C   . PRO C 2 227 ? 171.836 140.726 147.764 1.00 49.59  ? 227 PRO C C   1 
ATOM   9740  O  O   . PRO C 2 227 ? 172.627 140.796 148.706 1.00 49.59  ? 227 PRO C O   1 
ATOM   9741  C  CB  . PRO C 2 227 ? 169.682 139.999 148.862 1.00 49.59  ? 227 PRO C CB  1 
ATOM   9742  C  CG  . PRO C 2 227 ? 170.156 139.202 150.016 1.00 49.59  ? 227 PRO C CG  1 
ATOM   9743  C  CD  . PRO C 2 227 ? 170.768 137.957 149.452 1.00 49.59  ? 227 PRO C CD  1 
ATOM   9744  N  N   . LEU C 2 228 ? 171.897 141.522 146.707 1.00 49.55  ? 228 LEU C N   1 
ATOM   9745  C  CA  . LEU C 2 228 ? 172.936 142.519 146.512 1.00 49.55  ? 228 LEU C CA  1 
ATOM   9746  C  C   . LEU C 2 228 ? 172.334 143.919 146.537 1.00 49.55  ? 228 LEU C C   1 
ATOM   9747  O  O   . LEU C 2 228 ? 171.153 144.116 146.831 1.00 49.55  ? 228 LEU C O   1 
ATOM   9748  C  CB  . LEU C 2 228 ? 173.679 142.268 145.200 1.00 49.55  ? 228 LEU C CB  1 
ATOM   9749  C  CG  . LEU C 2 228 ? 174.575 141.036 145.141 1.00 49.55  ? 228 LEU C CG  1 
ATOM   9750  C  CD1 . LEU C 2 228 ? 175.078 140.821 143.734 1.00 49.55  ? 228 LEU C CD1 1 
ATOM   9751  C  CD2 . LEU C 2 228 ? 175.732 141.234 146.083 1.00 49.55  ? 228 LEU C CD2 1 
ATOM   9752  N  N   . ARG C 2 229 ? 173.176 144.899 146.230 1.00 55.19  ? 229 ARG C N   1 
ATOM   9753  C  CA  . ARG C 2 229 ? 172.765 146.286 146.089 1.00 55.19  ? 229 ARG C CA  1 
ATOM   9754  C  C   . ARG C 2 229 ? 173.303 146.843 144.781 1.00 55.19  ? 229 ARG C C   1 
ATOM   9755  O  O   . ARG C 2 229 ? 173.969 146.150 144.008 1.00 55.19  ? 229 ARG C O   1 
ATOM   9756  C  CB  . ARG C 2 229 ? 173.243 147.145 147.263 1.00 55.19  ? 229 ARG C CB  1 
ATOM   9757  C  CG  . ARG C 2 229 ? 172.471 146.940 148.543 1.00 55.19  ? 229 ARG C CG  1 
ATOM   9758  C  CD  . ARG C 2 229 ? 173.022 147.831 149.633 1.00 55.19  ? 229 ARG C CD  1 
ATOM   9759  N  NE  . ARG C 2 229 ? 172.235 147.748 150.856 1.00 55.19  ? 229 ARG C NE  1 
ATOM   9760  C  CZ  . ARG C 2 229 ? 172.547 148.373 151.984 1.00 55.19  ? 229 ARG C CZ  1 
ATOM   9761  N  NH1 . ARG C 2 229 ? 173.640 149.121 152.049 1.00 55.19  ? 229 ARG C NH1 1 
ATOM   9762  N  NH2 . ARG C 2 229 ? 171.767 148.248 153.045 1.00 55.19  ? 229 ARG C NH2 1 
ATOM   9763  N  N   . ASP C 2 230 ? 173.020 148.119 144.549 1.00 56.19  ? 230 ASP C N   1 
ATOM   9764  C  CA  . ASP C 2 230 ? 173.332 148.737 143.271 1.00 56.19  ? 230 ASP C CA  1 
ATOM   9765  C  C   . ASP C 2 230 ? 174.835 148.885 143.063 1.00 56.19  ? 230 ASP C C   1 
ATOM   9766  O  O   . ASP C 2 230 ? 175.630 148.805 144.001 1.00 56.19  ? 230 ASP C O   1 
ATOM   9767  C  CB  . ASP C 2 230 ? 172.654 150.104 143.170 1.00 56.19  ? 230 ASP C CB  1 
ATOM   9768  C  CG  . ASP C 2 230 ? 173.050 151.037 144.294 1.00 56.19  ? 230 ASP C CG  1 
ATOM   9769  O  OD1 . ASP C 2 230 ? 173.781 150.596 145.201 1.00 56.19  ? 230 ASP C OD1 1 
ATOM   9770  O  OD2 . ASP C 2 230 ? 172.630 152.213 144.273 1.00 56.19  ? 230 ASP C OD2 1 
ATOM   9771  N  N   . GLY C 2 231 ? 175.216 149.087 141.805 1.00 52.82  ? 231 GLY C N   1 
ATOM   9772  C  CA  . GLY C 2 231 ? 176.559 149.490 141.444 1.00 52.82  ? 231 GLY C CA  1 
ATOM   9773  C  C   . GLY C 2 231 ? 177.670 148.522 141.773 1.00 52.82  ? 231 GLY C C   1 
ATOM   9774  O  O   . GLY C 2 231 ? 178.836 148.931 141.762 1.00 52.82  ? 231 GLY C O   1 
ATOM   9775  N  N   . ILE C 2 232 ? 177.362 147.253 142.056 1.00 52.06  ? 232 ILE C N   1 
ATOM   9776  C  CA  . ILE C 2 232 ? 178.419 146.302 142.379 1.00 52.06  ? 232 ILE C CA  1 
ATOM   9777  C  C   . ILE C 2 232 ? 179.355 146.162 141.187 1.00 52.06  ? 232 ILE C C   1 
ATOM   9778  O  O   . ILE C 2 232 ? 178.929 145.881 140.060 1.00 52.06  ? 232 ILE C O   1 
ATOM   9779  C  CB  . ILE C 2 232 ? 177.827 144.952 142.820 1.00 52.06  ? 232 ILE C CB  1 
ATOM   9780  C  CG1 . ILE C 2 232 ? 178.931 144.023 143.322 1.00 52.06  ? 232 ILE C CG1 1 
ATOM   9781  C  CG2 . ILE C 2 232 ? 177.042 144.283 141.713 1.00 52.06  ? 232 ILE C CG2 1 
ATOM   9782  C  CD1 . ILE C 2 232 ? 178.418 142.801 144.035 1.00 52.06  ? 232 ILE C CD1 1 
ATOM   9783  N  N   . ASP C 2 233 ? 180.638 146.404 141.423 1.00 55.27  ? 233 ASP C N   1 
ATOM   9784  C  CA  . ASP C 2 233 ? 181.635 146.345 140.369 1.00 55.27  ? 233 ASP C CA  1 
ATOM   9785  C  C   . ASP C 2 233 ? 182.033 144.892 140.127 1.00 55.27  ? 233 ASP C C   1 
ATOM   9786  O  O   . ASP C 2 233 ? 181.322 143.960 140.506 1.00 55.27  ? 233 ASP C O   1 
ATOM   9787  C  CB  . ASP C 2 233 ? 182.823 147.238 140.719 1.00 55.27  ? 233 ASP C CB  1 
ATOM   9788  C  CG  . ASP C 2 233 ? 183.464 146.869 142.041 1.00 55.27  ? 233 ASP C CG  1 
ATOM   9789  O  OD1 . ASP C 2 233 ? 182.954 145.953 142.717 1.00 55.27  ? 233 ASP C OD1 1 
ATOM   9790  O  OD2 . ASP C 2 233 ? 184.478 147.499 142.409 1.00 55.27  ? 233 ASP C OD2 1 
ATOM   9791  N  N   . ASP C 2 234 ? 183.184 144.681 139.494 1.00 59.29  ? 234 ASP C N   1 
ATOM   9792  C  CA  . ASP C 2 234 ? 183.536 143.338 139.047 1.00 59.29  ? 234 ASP C CA  1 
ATOM   9793  C  C   . ASP C 2 234 ? 184.277 142.566 140.133 1.00 59.29  ? 234 ASP C C   1 
ATOM   9794  O  O   . ASP C 2 234 ? 183.957 141.402 140.408 1.00 59.29  ? 234 ASP C O   1 
ATOM   9795  C  CB  . ASP C 2 234 ? 184.369 143.427 137.770 1.00 59.29  ? 234 ASP C CB  1 
ATOM   9796  C  CG  . ASP C 2 234 ? 184.508 142.094 137.070 1.00 59.29  ? 234 ASP C CG  1 
ATOM   9797  O  OD1 . ASP C 2 234 ? 183.976 141.086 137.581 1.00 59.29  ? 234 ASP C OD1 1 
ATOM   9798  O  OD2 . ASP C 2 234 ? 185.149 142.055 136.000 1.00 59.29  ? 234 ASP C OD2 1 
ATOM   9799  N  N   . GLU C 2 235 ? 185.269 143.198 140.765 1.00 62.36  ? 235 GLU C N   1 
ATOM   9800  C  CA  . GLU C 2 235 ? 186.091 142.498 141.750 1.00 62.36  ? 235 GLU C CA  1 
ATOM   9801  C  C   . GLU C 2 235 ? 185.254 142.020 142.930 1.00 62.36  ? 235 GLU C C   1 
ATOM   9802  O  O   . GLU C 2 235 ? 185.476 140.925 143.461 1.00 62.36  ? 235 GLU C O   1 
ATOM   9803  C  CB  . GLU C 2 235 ? 187.225 143.404 142.226 1.00 62.36  ? 235 GLU C CB  1 
ATOM   9804  C  CG  . GLU C 2 235 ? 188.239 143.743 141.148 1.00 62.36  ? 235 GLU C CG  1 
ATOM   9805  C  CD  . GLU C 2 235 ? 187.816 144.929 140.305 1.00 62.36  ? 235 GLU C CD  1 
ATOM   9806  O  OE1 . GLU C 2 235 ? 186.769 145.536 140.613 1.00 62.36  ? 235 GLU C OE1 1 
ATOM   9807  O  OE2 . GLU C 2 235 ? 188.531 145.256 139.335 1.00 62.36  ? 235 GLU C OE2 1 
ATOM   9808  N  N   . SER C 2 236 ? 184.283 142.831 143.355 1.00 57.84  ? 236 SER C N   1 
ATOM   9809  C  CA  . SER C 2 236 ? 183.391 142.405 144.427 1.00 57.84  ? 236 SER C CA  1 
ATOM   9810  C  C   . SER C 2 236 ? 182.558 141.204 144.001 1.00 57.84  ? 236 SER C C   1 
ATOM   9811  O  O   . SER C 2 236 ? 182.399 140.244 144.765 1.00 57.84  ? 236 SER C O   1 
ATOM   9812  C  CB  . SER C 2 236 ? 182.486 143.561 144.848 1.00 57.84  ? 236 SER C CB  1 
ATOM   9813  O  OG  . SER C 2 236 ? 183.242 144.623 145.399 1.00 57.84  ? 236 SER C OG  1 
ATOM   9814  N  N   . TYR C 2 237 ? 182.033 141.232 142.773 1.00 56.07  ? 237 TYR C N   1 
ATOM   9815  C  CA  . TYR C 2 237 ? 181.170 140.149 142.318 1.00 56.07  ? 237 TYR C CA  1 
ATOM   9816  C  C   . TYR C 2 237 ? 181.955 138.853 142.175 1.00 56.07  ? 237 TYR C C   1 
ATOM   9817  O  O   . TYR C 2 237 ? 181.403 137.761 142.356 1.00 56.07  ? 237 TYR C O   1 
ATOM   9818  C  CB  . TYR C 2 237 ? 180.509 140.529 140.995 1.00 56.07  ? 237 TYR C CB  1 
ATOM   9819  C  CG  . TYR C 2 237 ? 179.387 139.612 140.574 1.00 56.07  ? 237 TYR C CG  1 
ATOM   9820  C  CD1 . TYR C 2 237 ? 178.129 139.731 141.143 1.00 56.07  ? 237 TYR C CD1 1 
ATOM   9821  C  CD2 . TYR C 2 237 ? 179.581 138.629 139.616 1.00 56.07  ? 237 TYR C CD2 1 
ATOM   9822  C  CE1 . TYR C 2 237 ? 177.095 138.908 140.770 1.00 56.07  ? 237 TYR C CE1 1 
ATOM   9823  C  CE2 . TYR C 2 237 ? 178.546 137.794 139.235 1.00 56.07  ? 237 TYR C CE2 1 
ATOM   9824  C  CZ  . TYR C 2 237 ? 177.306 137.940 139.821 1.00 56.07  ? 237 TYR C CZ  1 
ATOM   9825  O  OH  . TYR C 2 237 ? 176.280 137.109 139.442 1.00 56.07  ? 237 TYR C OH  1 
ATOM   9826  N  N   . GLU C 2 238 ? 183.247 138.951 141.852 1.00 58.31  ? 238 GLU C N   1 
ATOM   9827  C  CA  . GLU C 2 238 ? 184.086 137.757 141.831 1.00 58.31  ? 238 GLU C CA  1 
ATOM   9828  C  C   . GLU C 2 238 ? 184.365 137.260 143.242 1.00 58.31  ? 238 GLU C C   1 
ATOM   9829  O  O   . GLU C 2 238 ? 184.202 136.067 143.532 1.00 58.31  ? 238 GLU C O   1 
ATOM   9830  C  CB  . GLU C 2 238 ? 185.394 138.042 141.096 1.00 58.31  ? 238 GLU C CB  1 
ATOM   9831  C  CG  . GLU C 2 238 ? 185.211 138.355 139.627 1.00 58.31  ? 238 GLU C CG  1 
ATOM   9832  C  CD  . GLU C 2 238 ? 184.659 137.177 138.852 1.00 58.31  ? 238 GLU C CD  1 
ATOM   9833  O  OE1 . GLU C 2 238 ? 184.968 136.023 139.219 1.00 58.31  ? 238 GLU C OE1 1 
ATOM   9834  O  OE2 . GLU C 2 238 ? 183.909 137.405 137.881 1.00 58.31  ? 238 GLU C OE2 1 
ATOM   9835  N  N   . ALA C 2 239 ? 184.772 138.167 144.136 1.00 56.58  ? 239 ALA C N   1 
ATOM   9836  C  CA  . ALA C 2 239 ? 185.088 137.789 145.508 1.00 56.58  ? 239 ALA C CA  1 
ATOM   9837  C  C   . ALA C 2 239 ? 183.886 137.226 146.253 1.00 56.58  ? 239 ALA C C   1 
ATOM   9838  O  O   . ALA C 2 239 ? 184.070 136.522 147.250 1.00 56.58  ? 239 ALA C O   1 
ATOM   9839  C  CB  . ALA C 2 239 ? 185.653 138.988 146.270 1.00 56.58  ? 239 ALA C CB  1 
ATOM   9840  N  N   . ILE C 2 240 ? 182.665 137.520 145.805 1.00 54.72  ? 240 ILE C N   1 
ATOM   9841  C  CA  . ILE C 2 240 ? 181.494 136.887 146.401 1.00 54.72  ? 240 ILE C CA  1 
ATOM   9842  C  C   . ILE C 2 240 ? 181.001 135.693 145.593 1.00 54.72  ? 240 ILE C C   1 
ATOM   9843  O  O   . ILE C 2 240 ? 180.298 134.834 146.142 1.00 54.72  ? 240 ILE C O   1 
ATOM   9844  C  CB  . ILE C 2 240 ? 180.342 137.890 146.577 1.00 54.72  ? 240 ILE C CB  1 
ATOM   9845  C  CG1 . ILE C 2 240 ? 179.852 138.380 145.218 1.00 54.72  ? 240 ILE C CG1 1 
ATOM   9846  C  CG2 . ILE C 2 240 ? 180.787 139.060 147.430 1.00 54.72  ? 240 ILE C CG2 1 
ATOM   9847  C  CD1 . ILE C 2 240 ? 178.584 139.174 145.283 1.00 54.72  ? 240 ILE C CD1 1 
ATOM   9848  N  N   . PHE C 2 241 ? 181.351 135.607 144.310 1.00 53.96  ? 241 PHE C N   1 
ATOM   9849  C  CA  . PHE C 2 241 ? 180.902 134.493 143.487 1.00 53.96  ? 241 PHE C CA  1 
ATOM   9850  C  C   . PHE C 2 241 ? 181.730 133.236 143.709 1.00 53.96  ? 241 PHE C C   1 
ATOM   9851  O  O   . PHE C 2 241 ? 181.173 132.136 143.769 1.00 53.96  ? 241 PHE C O   1 
ATOM   9852  C  CB  . PHE C 2 241 ? 180.944 134.874 142.006 1.00 53.96  ? 241 PHE C CB  1 
ATOM   9853  C  CG  . PHE C 2 241 ? 180.395 133.814 141.092 1.00 53.96  ? 241 PHE C CG  1 
ATOM   9854  C  CD1 . PHE C 2 241 ? 179.032 133.655 140.938 1.00 53.96  ? 241 PHE C CD1 1 
ATOM   9855  C  CD2 . PHE C 2 241 ? 181.240 132.968 140.398 1.00 53.96  ? 241 PHE C CD2 1 
ATOM   9856  C  CE1 . PHE C 2 241 ? 178.520 132.683 140.107 1.00 53.96  ? 241 PHE C CE1 1 
ATOM   9857  C  CE2 . PHE C 2 241 ? 180.731 131.992 139.564 1.00 53.96  ? 241 PHE C CE2 1 
ATOM   9858  C  CZ  . PHE C 2 241 ? 179.370 131.852 139.420 1.00 53.96  ? 241 PHE C CZ  1 
ATOM   9859  N  N   . LYS C 2 242 ? 183.051 133.367 143.830 1.00 56.44  ? 242 LYS C N   1 
ATOM   9860  C  CA  . LYS C 2 242 ? 183.895 132.176 143.921 1.00 56.44  ? 242 LYS C CA  1 
ATOM   9861  C  C   . LYS C 2 242 ? 183.694 131.393 145.215 1.00 56.44  ? 242 LYS C C   1 
ATOM   9862  O  O   . LYS C 2 242 ? 183.435 130.178 145.138 1.00 56.44  ? 242 LYS C O   1 
ATOM   9863  C  CB  . LYS C 2 242 ? 185.361 132.572 143.720 1.00 56.44  ? 242 LYS C CB  1 
ATOM   9864  C  CG  . LYS C 2 242 ? 185.685 133.029 142.309 1.00 56.44  ? 242 LYS C CG  1 
ATOM   9865  C  CD  . LYS C 2 242 ? 187.121 133.514 142.202 1.00 56.44  ? 242 LYS C CD  1 
ATOM   9866  C  CE  . LYS C 2 242 ? 188.114 132.368 142.284 1.00 56.44  ? 242 LYS C CE  1 
ATOM   9867  N  NZ  . LYS C 2 242 ? 188.060 131.498 141.080 1.00 56.44  ? 242 LYS C NZ  1 
ATOM   9868  N  N   . PRO C 2 243 ? 183.786 131.989 146.413 1.00 56.93  ? 243 PRO C N   1 
ATOM   9869  C  CA  . PRO C 2 243 ? 183.684 131.162 147.627 1.00 56.93  ? 243 PRO C CA  1 
ATOM   9870  C  C   . PRO C 2 243 ? 182.332 130.498 147.796 1.00 56.93  ? 243 PRO C C   1 
ATOM   9871  O  O   . PRO C 2 243 ? 182.271 129.313 148.150 1.00 56.93  ? 243 PRO C O   1 
ATOM   9872  C  CB  . PRO C 2 243 ? 183.960 132.163 148.756 1.00 56.93  ? 243 PRO C CB  1 
ATOM   9873  C  CG  . PRO C 2 243 ? 184.691 133.280 148.112 1.00 56.93  ? 243 PRO C CG  1 
ATOM   9874  C  CD  . PRO C 2 243 ? 184.095 133.389 146.749 1.00 56.93  ? 243 PRO C CD  1 
ATOM   9875  N  N   . VAL C 2 244 ? 181.243 131.231 147.559 1.00 57.56  ? 244 VAL C N   1 
ATOM   9876  C  CA  . VAL C 2 244 ? 179.910 130.670 147.754 1.00 57.56  ? 244 VAL C CA  1 
ATOM   9877  C  C   . VAL C 2 244 ? 179.685 129.490 146.820 1.00 57.56  ? 244 VAL C C   1 
ATOM   9878  O  O   . VAL C 2 244 ? 179.104 128.472 147.214 1.00 57.56  ? 244 VAL C O   1 
ATOM   9879  C  CB  . VAL C 2 244 ? 178.837 131.757 147.560 1.00 57.56  ? 244 VAL C CB  1 
ATOM   9880  C  CG1 . VAL C 2 244 ? 177.451 131.155 147.679 1.00 57.56  ? 244 VAL C CG1 1 
ATOM   9881  C  CG2 . VAL C 2 244 ? 179.025 132.873 148.572 1.00 57.56  ? 244 VAL C CG2 1 
ATOM   9882  N  N   . MET C 2 245 ? 180.150 129.595 145.573 1.00 55.61  ? 245 MET C N   1 
ATOM   9883  C  CA  . MET C 2 245 ? 179.929 128.507 144.627 1.00 55.61  ? 245 MET C CA  1 
ATOM   9884  C  C   . MET C 2 245 ? 180.853 127.329 144.904 1.00 55.61  ? 245 MET C C   1 
ATOM   9885  O  O   . MET C 2 245 ? 180.479 126.176 144.662 1.00 55.61  ? 245 MET C O   1 
ATOM   9886  C  CB  . MET C 2 245 ? 180.095 129.001 143.193 1.00 55.61  ? 245 MET C CB  1 
ATOM   9887  C  CG  . MET C 2 245 ? 179.024 129.983 142.773 1.00 55.61  ? 245 MET C CG  1 
ATOM   9888  S  SD  . MET C 2 245 ? 177.379 129.312 143.046 1.00 55.61  ? 245 MET C SD  1 
ATOM   9889  C  CE  . MET C 2 245 ? 177.409 127.920 141.932 1.00 55.61  ? 245 MET C CE  1 
ATOM   9890  N  N   . SER C 2 246 ? 182.060 127.588 145.412 1.00 57.20  ? 246 SER C N   1 
ATOM   9891  C  CA  . SER C 2 246 ? 182.894 126.479 145.865 1.00 57.20  ? 246 SER C CA  1 
ATOM   9892  C  C   . SER C 2 246 ? 182.235 125.744 147.026 1.00 57.20  ? 246 SER C C   1 
ATOM   9893  O  O   . SER C 2 246 ? 182.304 124.511 147.113 1.00 57.20  ? 246 SER C O   1 
ATOM   9894  C  CB  . SER C 2 246 ? 184.278 126.985 146.262 1.00 57.20  ? 246 SER C CB  1 
ATOM   9895  O  OG  . SER C 2 246 ? 184.970 127.508 145.143 1.00 57.20  ? 246 SER C OG  1 
ATOM   9896  N  N   . LYS C 2 247 ? 181.573 126.485 147.917 1.00 59.85  ? 247 LYS C N   1 
ATOM   9897  C  CA  . LYS C 2 247 ? 180.891 125.854 149.042 1.00 59.85  ? 247 LYS C CA  1 
ATOM   9898  C  C   . LYS C 2 247 ? 179.658 125.086 148.584 1.00 59.85  ? 247 LYS C C   1 
ATOM   9899  O  O   . LYS C 2 247 ? 179.336 124.029 149.140 1.00 59.85  ? 247 LYS C O   1 
ATOM   9900  C  CB  . LYS C 2 247 ? 180.515 126.908 150.082 1.00 59.85  ? 247 LYS C CB  1 
ATOM   9901  C  CG  . LYS C 2 247 ? 179.821 126.349 151.309 1.00 59.85  ? 247 LYS C CG  1 
ATOM   9902  C  CD  . LYS C 2 247 ? 180.718 125.368 152.036 1.00 59.85  ? 247 LYS C CD  1 
ATOM   9903  C  CE  . LYS C 2 247 ? 181.901 126.070 152.672 1.00 59.85  ? 247 LYS C CE  1 
ATOM   9904  N  NZ  . LYS C 2 247 ? 182.763 125.108 153.406 1.00 59.85  ? 247 LYS C NZ  1 
ATOM   9905  N  N   . VAL C 2 248 ? 178.952 125.599 147.575 1.00 55.04  ? 248 VAL C N   1 
ATOM   9906  C  CA  . VAL C 2 248 ? 177.781 124.893 147.058 1.00 55.04  ? 248 VAL C CA  1 
ATOM   9907  C  C   . VAL C 2 248 ? 178.204 123.610 146.355 1.00 55.04  ? 248 VAL C C   1 
ATOM   9908  O  O   . VAL C 2 248 ? 177.571 122.559 146.510 1.00 55.04  ? 248 VAL C O   1 
ATOM   9909  C  CB  . VAL C 2 248 ? 176.965 125.807 146.129 1.00 55.04  ? 248 VAL C CB  1 
ATOM   9910  C  CG1 . VAL C 2 248 ? 175.881 125.012 145.436 1.00 55.04  ? 248 VAL C CG1 1 
ATOM   9911  C  CG2 . VAL C 2 248 ? 176.344 126.939 146.922 1.00 55.04  ? 248 VAL C CG2 1 
ATOM   9912  N  N   . MET C 2 249 ? 179.285 123.674 145.573 1.00 58.28  ? 249 MET C N   1 
ATOM   9913  C  CA  . MET C 2 249 ? 179.810 122.461 144.955 1.00 58.28  ? 249 MET C CA  1 
ATOM   9914  C  C   . MET C 2 249 ? 180.286 121.459 145.998 1.00 58.28  ? 249 MET C C   1 
ATOM   9915  O  O   . MET C 2 249 ? 180.122 120.249 145.812 1.00 58.28  ? 249 MET C O   1 
ATOM   9916  C  CB  . MET C 2 249 ? 180.958 122.797 144.006 1.00 58.28  ? 249 MET C CB  1 
ATOM   9917  C  CG  . MET C 2 249 ? 180.565 123.589 142.776 1.00 58.28  ? 249 MET C CG  1 
ATOM   9918  S  SD  . MET C 2 249 ? 179.490 122.678 141.657 1.00 58.28  ? 249 MET C SD  1 
ATOM   9919  C  CE  . MET C 2 249 ? 179.121 123.954 140.456 1.00 58.28  ? 249 MET C CE  1 
ATOM   9920  N  N   . GLU C 2 250 ? 180.876 121.938 147.095 1.00 59.83  ? 250 GLU C N   1 
ATOM   9921  C  CA  . GLU C 2 250 ? 181.422 121.019 148.088 1.00 59.83  ? 250 GLU C CA  1 
ATOM   9922  C  C   . GLU C 2 250 ? 180.320 120.360 148.910 1.00 59.83  ? 250 GLU C C   1 
ATOM   9923  O  O   . GLU C 2 250 ? 180.345 119.144 149.127 1.00 59.83  ? 250 GLU C O   1 
ATOM   9924  C  CB  . GLU C 2 250 ? 182.405 121.756 148.995 1.00 59.83  ? 250 GLU C CB  1 
ATOM   9925  C  CG  . GLU C 2 250 ? 183.098 120.867 150.008 1.00 59.83  ? 250 GLU C CG  1 
ATOM   9926  C  CD  . GLU C 2 250 ? 184.095 121.626 150.858 1.00 59.83  ? 250 GLU C CD  1 
ATOM   9927  O  OE1 . GLU C 2 250 ? 184.228 122.853 150.668 1.00 59.83  ? 250 GLU C OE1 1 
ATOM   9928  O  OE2 . GLU C 2 250 ? 184.747 120.995 151.717 1.00 59.83  ? 250 GLU C OE2 1 
ATOM   9929  N  N   . MET C 2 251 ? 179.346 121.143 149.373 1.00 60.44  ? 251 MET C N   1 
ATOM   9930  C  CA  . MET C 2 251 ? 178.278 120.635 150.226 1.00 60.44  ? 251 MET C CA  1 
ATOM   9931  C  C   . MET C 2 251 ? 177.177 119.916 149.460 1.00 60.44  ? 251 MET C C   1 
ATOM   9932  O  O   . MET C 2 251 ? 176.740 118.845 149.895 1.00 60.44  ? 251 MET C O   1 
ATOM   9933  C  CB  . MET C 2 251 ? 177.655 121.778 151.035 1.00 60.44  ? 251 MET C CB  1 
ATOM   9934  C  CG  . MET C 2 251 ? 178.572 122.393 152.080 1.00 60.44  ? 251 MET C CG  1 
ATOM   9935  S  SD  . MET C 2 251 ? 179.062 121.234 153.371 1.00 60.44  ? 251 MET C SD  1 
ATOM   9936  C  CE  . MET C 2 251 ? 180.753 120.881 152.900 1.00 60.44  ? 251 MET C CE  1 
ATOM   9937  N  N   . PHE C 2 252 ? 176.716 120.471 148.343 1.00 53.51  ? 252 PHE C N   1 
ATOM   9938  C  CA  . PHE C 2 252 ? 175.598 119.918 147.588 1.00 53.51  ? 252 PHE C CA  1 
ATOM   9939  C  C   . PHE C 2 252 ? 175.984 118.754 146.692 1.00 53.51  ? 252 PHE C C   1 
ATOM   9940  O  O   . PHE C 2 252 ? 175.217 117.796 146.581 1.00 53.51  ? 252 PHE C O   1 
ATOM   9941  C  CB  . PHE C 2 252 ? 174.949 121.019 146.743 1.00 53.51  ? 252 PHE C CB  1 
ATOM   9942  C  CG  . PHE C 2 252 ? 173.773 120.557 145.939 1.00 53.51  ? 252 PHE C CG  1 
ATOM   9943  C  CD1 . PHE C 2 252 ? 172.579 120.236 146.555 1.00 53.51  ? 252 PHE C CD1 1 
ATOM   9944  C  CD2 . PHE C 2 252 ? 173.849 120.476 144.563 1.00 53.51  ? 252 PHE C CD2 1 
ATOM   9945  C  CE1 . PHE C 2 252 ? 171.491 119.821 145.818 1.00 53.51  ? 252 PHE C CE1 1 
ATOM   9946  C  CE2 . PHE C 2 252 ? 172.763 120.064 143.822 1.00 53.51  ? 252 PHE C CE2 1 
ATOM   9947  C  CZ  . PHE C 2 252 ? 171.582 119.736 144.451 1.00 53.51  ? 252 PHE C CZ  1 
ATOM   9948  N  N   . GLN C 2 253 ? 177.158 118.808 146.058 1.00 56.66  ? 253 GLN C N   1 
ATOM   9949  C  CA  . GLN C 2 253 ? 177.631 117.777 145.141 1.00 56.66  ? 253 GLN C CA  1 
ATOM   9950  C  C   . GLN C 2 253 ? 176.613 117.531 144.034 1.00 56.66  ? 253 GLN C C   1 
ATOM   9951  O  O   . GLN C 2 253 ? 175.889 116.528 144.072 1.00 56.66  ? 253 GLN C O   1 
ATOM   9952  C  CB  . GLN C 2 253 ? 177.920 116.476 145.892 1.00 56.66  ? 253 GLN C CB  1 
ATOM   9953  C  CG  . GLN C 2 253 ? 179.077 116.558 146.865 1.00 56.66  ? 253 GLN C CG  1 
ATOM   9954  C  CD  . GLN C 2 253 ? 180.407 116.728 146.164 1.00 56.66  ? 253 GLN C CD  1 
ATOM   9955  O  OE1 . GLN C 2 253 ? 180.647 116.135 145.113 1.00 56.66  ? 253 GLN C OE1 1 
ATOM   9956  N  NE2 . GLN C 2 253 ? 181.282 117.539 146.744 1.00 56.66  ? 253 GLN C NE2 1 
ATOM   9957  N  N   . PRO C 2 254 ? 176.518 118.413 143.043 1.00 51.77  ? 254 PRO C N   1 
ATOM   9958  C  CA  . PRO C 2 254 ? 175.557 118.207 141.959 1.00 51.77  ? 254 PRO C CA  1 
ATOM   9959  C  C   . PRO C 2 254 ? 176.076 117.213 140.933 1.00 51.77  ? 254 PRO C C   1 
ATOM   9960  O  O   . PRO C 2 254 ? 177.177 116.672 141.042 1.00 51.77  ? 254 PRO C O   1 
ATOM   9961  C  CB  . PRO C 2 254 ? 175.420 119.602 141.345 1.00 51.77  ? 254 PRO C CB  1 
ATOM   9962  C  CG  . PRO C 2 254 ? 176.737 120.231 141.594 1.00 51.77  ? 254 PRO C CG  1 
ATOM   9963  C  CD  . PRO C 2 254 ? 177.209 119.708 142.925 1.00 51.77  ? 254 PRO C CD  1 
ATOM   9964  N  N   . SER C 2 255 ? 175.248 116.981 139.917 1.00 49.08  ? 255 SER C N   1 
ATOM   9965  C  CA  . SER C 2 255 ? 175.624 116.146 138.785 1.00 49.08  ? 255 SER C CA  1 
ATOM   9966  C  C   . SER C 2 255 ? 175.553 116.880 137.455 1.00 49.08  ? 255 SER C C   1 
ATOM   9967  O  O   . SER C 2 255 ? 176.256 116.500 136.514 1.00 49.08  ? 255 SER C O   1 
ATOM   9968  C  CB  . SER C 2 255 ? 174.734 114.902 138.724 1.00 49.08  ? 255 SER C CB  1 
ATOM   9969  O  OG  . SER C 2 255 ? 174.930 114.083 139.863 1.00 49.08  ? 255 SER C OG  1 
ATOM   9970  N  N   . ALA C 2 256 ? 174.724 117.916 137.357 1.00 43.95  ? 256 ALA C N   1 
ATOM   9971  C  CA  . ALA C 2 256 ? 174.644 118.753 136.171 1.00 43.95  ? 256 ALA C CA  1 
ATOM   9972  C  C   . ALA C 2 256 ? 174.385 120.188 136.601 1.00 43.95  ? 256 ALA C C   1 
ATOM   9973  O  O   . ALA C 2 256 ? 173.798 120.445 137.655 1.00 43.95  ? 256 ALA C O   1 
ATOM   9974  C  CB  . ALA C 2 256 ? 173.550 118.281 135.210 1.00 43.95  ? 256 ALA C CB  1 
ATOM   9975  N  N   . VAL C 2 257 ? 174.826 121.127 135.768 1.00 38.46  ? 257 VAL C N   1 
ATOM   9976  C  CA  . VAL C 2 257 ? 174.748 122.548 136.080 1.00 38.46  ? 257 VAL C CA  1 
ATOM   9977  C  C   . VAL C 2 257 ? 173.954 123.249 134.990 1.00 38.46  ? 257 VAL C C   1 
ATOM   9978  O  O   . VAL C 2 257 ? 174.179 123.009 133.799 1.00 38.46  ? 257 VAL C O   1 
ATOM   9979  C  CB  . VAL C 2 257 ? 176.147 123.178 136.221 1.00 38.46  ? 257 VAL C CB  1 
ATOM   9980  C  CG1 . VAL C 2 257 ? 176.038 124.667 136.473 1.00 38.46  ? 257 VAL C CG1 1 
ATOM   9981  C  CG2 . VAL C 2 257 ? 176.914 122.507 137.341 1.00 38.46  ? 257 VAL C CG2 1 
ATOM   9982  N  N   . VAL C 2 258 ? 173.025 124.110 135.397 1.00 36.50  ? 258 VAL C N   1 
ATOM   9983  C  CA  . VAL C 2 258 ? 172.253 124.945 134.487 1.00 36.50  ? 258 VAL C CA  1 
ATOM   9984  C  C   . VAL C 2 258 ? 172.557 126.396 134.826 1.00 36.50  ? 258 VAL C C   1 
ATOM   9985  O  O   . VAL C 2 258 ? 172.062 126.923 135.831 1.00 36.50  ? 258 VAL C O   1 
ATOM   9986  C  CB  . VAL C 2 258 ? 170.746 124.660 134.580 1.00 36.50  ? 258 VAL C CB  1 
ATOM   9987  C  CG1 . VAL C 2 258 ? 169.973 125.591 133.662 1.00 36.50  ? 258 VAL C CG1 1 
ATOM   9988  C  CG2 . VAL C 2 258 ? 170.462 123.215 134.232 1.00 36.50  ? 258 VAL C CG2 1 
ATOM   9989  N  N   . LEU C 2 259 ? 173.379 127.033 134.001 1.00 39.40  ? 259 LEU C N   1 
ATOM   9990  C  CA  . LEU C 2 259 ? 173.759 128.427 134.170 1.00 39.40  ? 259 LEU C CA  1 
ATOM   9991  C  C   . LEU C 2 259 ? 172.835 129.310 133.346 1.00 39.40  ? 259 LEU C C   1 
ATOM   9992  O  O   . LEU C 2 259 ? 172.740 129.144 132.126 1.00 39.40  ? 259 LEU C O   1 
ATOM   9993  C  CB  . LEU C 2 259 ? 175.208 128.653 133.742 1.00 39.40  ? 259 LEU C CB  1 
ATOM   9994  C  CG  . LEU C 2 259 ? 175.710 130.088 133.898 1.00 39.40  ? 259 LEU C CG  1 
ATOM   9995  C  CD1 . LEU C 2 259 ? 175.717 130.478 135.351 1.00 39.40  ? 259 LEU C CD1 1 
ATOM   9996  C  CD2 . LEU C 2 259 ? 177.086 130.266 133.302 1.00 39.40  ? 259 LEU C CD2 1 
ATOM   9997  N  N   . GLN C 2 260 ? 172.164 130.249 134.005 1.00 40.36  ? 260 GLN C N   1 
ATOM   9998  C  CA  . GLN C 2 260 ? 171.304 131.214 133.321 1.00 40.36  ? 260 GLN C CA  1 
ATOM   9999  C  C   . GLN C 2 260 ? 172.109 132.502 133.197 1.00 40.36  ? 260 GLN C C   1 
ATOM   10000 O  O   . GLN C 2 260 ? 171.934 133.446 133.964 1.00 40.36  ? 260 GLN C O   1 
ATOM   10001 C  CB  . GLN C 2 260 ? 169.995 131.413 134.073 1.00 40.36  ? 260 GLN C CB  1 
ATOM   10002 C  CG  . GLN C 2 260 ? 168.918 132.138 133.284 1.00 40.36  ? 260 GLN C CG  1 
ATOM   10003 C  CD  . GLN C 2 260 ? 168.957 133.635 133.469 1.00 40.36  ? 260 GLN C CD  1 
ATOM   10004 O  OE1 . GLN C 2 260 ? 169.336 134.128 134.526 1.00 40.36  ? 260 GLN C OE1 1 
ATOM   10005 N  NE2 . GLN C 2 260 ? 168.559 134.370 132.439 1.00 40.36  ? 260 GLN C NE2 1 
ATOM   10006 N  N   . CYS C 2 261 ? 173.012 132.528 132.216 1.00 44.51  ? 261 CYS C N   1 
ATOM   10007 C  CA  . CYS C 2 261 ? 173.958 133.628 132.040 1.00 44.51  ? 261 CYS C CA  1 
ATOM   10008 C  C   . CYS C 2 261 ? 173.253 134.873 131.498 1.00 44.51  ? 261 CYS C C   1 
ATOM   10009 O  O   . CYS C 2 261 ? 173.372 135.243 130.331 1.00 44.51  ? 261 CYS C O   1 
ATOM   10010 C  CB  . CYS C 2 261 ? 175.092 133.191 131.124 1.00 44.51  ? 261 CYS C CB  1 
ATOM   10011 S  SG  . CYS C 2 261 ? 176.378 134.428 130.889 1.00 44.51  ? 261 CYS C SG  1 
ATOM   10012 N  N   . GLY C 2 262 ? 172.508 135.527 132.382 1.00 42.97  ? 262 GLY C N   1 
ATOM   10013 C  CA  . GLY C 2 262 ? 171.787 136.725 132.007 1.00 42.97  ? 262 GLY C CA  1 
ATOM   10014 C  C   . GLY C 2 262 ? 172.685 137.932 131.845 1.00 42.97  ? 262 GLY C C   1 
ATOM   10015 O  O   . GLY C 2 262 ? 173.312 138.380 132.807 1.00 42.97  ? 262 GLY C O   1 
ATOM   10016 N  N   . SER C 2 263 ? 172.747 138.472 130.629 1.00 43.61  ? 263 SER C N   1 
ATOM   10017 C  CA  . SER C 2 263 ? 173.559 139.642 130.327 1.00 43.61  ? 263 SER C CA  1 
ATOM   10018 C  C   . SER C 2 263 ? 172.885 140.944 130.728 1.00 43.61  ? 263 SER C C   1 
ATOM   10019 O  O   . SER C 2 263 ? 173.135 141.980 130.102 1.00 43.61  ? 263 SER C O   1 
ATOM   10020 C  CB  . SER C 2 263 ? 173.899 139.678 128.838 1.00 43.61  ? 263 SER C CB  1 
ATOM   10021 O  OG  . SER C 2 263 ? 174.641 140.841 128.523 1.00 43.61  ? 263 SER C OG  1 
ATOM   10022 N  N   . ASP C 2 264 ? 172.045 140.919 131.755 1.00 46.45  ? 264 ASP C N   1 
ATOM   10023 C  CA  . ASP C 2 264 ? 171.275 142.091 132.130 1.00 46.45  ? 264 ASP C CA  1 
ATOM   10024 C  C   . ASP C 2 264 ? 171.806 142.764 133.385 1.00 46.45  ? 264 ASP C C   1 
ATOM   10025 O  O   . ASP C 2 264 ? 171.121 143.617 133.956 1.00 46.45  ? 264 ASP C O   1 
ATOM   10026 C  CB  . ASP C 2 264 ? 169.807 141.705 132.317 1.00 46.45  ? 264 ASP C CB  1 
ATOM   10027 C  CG  . ASP C 2 264 ? 168.903 142.901 132.378 1.00 46.45  ? 264 ASP C CG  1 
ATOM   10028 O  OD1 . ASP C 2 264 ? 168.808 143.608 131.360 1.00 46.45  ? 264 ASP C OD1 1 
ATOM   10029 O  OD2 . ASP C 2 264 ? 168.272 143.130 133.423 1.00 46.45  ? 264 ASP C OD2 1 
ATOM   10030 N  N   . SER C 2 265 ? 173.007 142.405 133.821 1.00 47.15  ? 265 SER C N   1 
ATOM   10031 C  CA  . SER C 2 265 ? 173.653 143.045 134.955 1.00 47.15  ? 265 SER C CA  1 
ATOM   10032 C  C   . SER C 2 265 ? 174.941 143.757 134.571 1.00 47.15  ? 265 SER C C   1 
ATOM   10033 O  O   . SER C 2 265 ? 175.786 143.982 135.440 1.00 47.15  ? 265 SER C O   1 
ATOM   10034 C  CB  . SER C 2 265 ? 173.940 142.009 136.045 1.00 47.15  ? 265 SER C CB  1 
ATOM   10035 O  OG  . SER C 2 265 ? 174.875 141.048 135.594 1.00 47.15  ? 265 SER C OG  1 
ATOM   10036 N  N   . LEU C 2 266 ? 175.111 144.112 133.301 1.00 48.07  ? 266 LEU C N   1 
ATOM   10037 C  CA  . LEU C 2 266 ? 176.331 144.758 132.835 1.00 48.07  ? 266 LEU C CA  1 
ATOM   10038 C  C   . LEU C 2 266 ? 176.322 146.237 133.214 1.00 48.07  ? 266 LEU C C   1 
ATOM   10039 O  O   . LEU C 2 266 ? 175.566 146.686 134.079 1.00 48.07  ? 266 LEU C O   1 
ATOM   10040 C  CB  . LEU C 2 266 ? 176.492 144.567 131.330 1.00 48.07  ? 266 LEU C CB  1 
ATOM   10041 C  CG  . LEU C 2 266 ? 176.841 143.170 130.827 1.00 48.07  ? 266 LEU C CG  1 
ATOM   10042 C  CD1 . LEU C 2 266 ? 176.786 143.129 129.321 1.00 48.07  ? 266 LEU C CD1 1 
ATOM   10043 C  CD2 . LEU C 2 266 ? 178.222 142.791 131.301 1.00 48.07  ? 266 LEU C CD2 1 
ATOM   10044 N  N   . SER C 2 267 ? 177.164 147.014 132.540 1.00 52.58  ? 267 SER C N   1 
ATOM   10045 C  CA  . SER C 2 267 ? 177.401 148.411 132.872 1.00 52.58  ? 267 SER C CA  1 
ATOM   10046 C  C   . SER C 2 267 ? 176.138 149.225 132.631 1.00 52.58  ? 267 SER C C   1 
ATOM   10047 O  O   . SER C 2 267 ? 175.545 149.749 133.580 1.00 52.58  ? 267 SER C O   1 
ATOM   10048 C  CB  . SER C 2 267 ? 178.561 148.968 132.049 1.00 52.58  ? 267 SER C CB  1 
ATOM   10049 O  OG  . SER C 2 267 ? 178.775 150.334 132.344 1.00 52.58  ? 267 SER C OG  1 
ATOM   10050 N  N   . GLY C 2 268 ? 175.734 149.336 131.375 1.00 51.32  ? 268 GLY C N   1 
ATOM   10051 C  CA  . GLY C 2 268 ? 174.626 150.179 130.996 1.00 51.32  ? 268 GLY C CA  1 
ATOM   10052 C  C   . GLY C 2 268 ? 173.479 149.516 130.258 1.00 51.32  ? 268 GLY C C   1 
ATOM   10053 O  O   . GLY C 2 268 ? 173.531 149.436 129.025 1.00 51.32  ? 268 GLY C O   1 
ATOM   10054 N  N   . ASP C 2 269 ? 172.455 149.043 130.961 1.00 49.65  ? 269 ASP C N   1 
ATOM   10055 C  CA  . ASP C 2 269 ? 171.262 148.554 130.293 1.00 49.65  ? 269 ASP C CA  1 
ATOM   10056 C  C   . ASP C 2 269 ? 170.180 149.626 130.279 1.00 49.65  ? 269 ASP C C   1 
ATOM   10057 O  O   . ASP C 2 269 ? 170.244 150.622 131.003 1.00 49.65  ? 269 ASP C O   1 
ATOM   10058 C  CB  . ASP C 2 269 ? 170.716 147.302 130.977 1.00 49.65  ? 269 ASP C CB  1 
ATOM   10059 C  CG  . ASP C 2 269 ? 171.592 146.094 130.768 1.00 49.65  ? 269 ASP C CG  1 
ATOM   10060 O  OD1 . ASP C 2 269 ? 172.307 146.036 129.746 1.00 49.65  ? 269 ASP C OD1 1 
ATOM   10061 O  OD2 . ASP C 2 269 ? 171.549 145.189 131.620 1.00 49.65  ? 269 ASP C OD2 1 
ATOM   10062 N  N   . ARG C 2 270 ? 169.171 149.407 129.433 1.00 51.48  ? 270 ARG C N   1 
ATOM   10063 C  CA  . ARG C 2 270 ? 167.943 150.182 129.540 1.00 51.48  ? 270 ARG C CA  1 
ATOM   10064 C  C   . ARG C 2 270 ? 167.304 150.010 130.910 1.00 51.48  ? 270 ARG C C   1 
ATOM   10065 O  O   . ARG C 2 270 ? 166.586 150.900 131.378 1.00 51.48  ? 270 ARG C O   1 
ATOM   10066 C  CB  . ARG C 2 270 ? 166.954 149.755 128.456 1.00 51.48  ? 270 ARG C CB  1 
ATOM   10067 C  CG  . ARG C 2 270 ? 167.393 150.013 127.029 1.00 51.48  ? 270 ARG C CG  1 
ATOM   10068 C  CD  . ARG C 2 270 ? 167.359 151.488 126.687 1.00 51.48  ? 270 ARG C CD  1 
ATOM   10069 N  NE  . ARG C 2 270 ? 167.586 151.713 125.263 1.00 51.48  ? 270 ARG C NE  1 
ATOM   10070 C  CZ  . ARG C 2 270 ? 168.781 151.907 124.718 1.00 51.48  ? 270 ARG C CZ  1 
ATOM   10071 N  NH1 . ARG C 2 270 ? 169.866 151.907 125.478 1.00 51.48  ? 270 ARG C NH1 1 
ATOM   10072 N  NH2 . ARG C 2 270 ? 168.891 152.102 123.412 1.00 51.48  ? 270 ARG C NH2 1 
ATOM   10073 N  N   . LEU C 2 271 ? 167.562 148.876 131.564 1.00 50.13  ? 271 LEU C N   1 
ATOM   10074 C  CA  . LEU C 2 271 ? 166.910 148.499 132.806 1.00 50.13  ? 271 LEU C CA  1 
ATOM   10075 C  C   . LEU C 2 271 ? 167.860 147.925 133.843 1.00 50.13  ? 271 LEU C C   1 
ATOM   10076 O  O   . LEU C 2 271 ? 167.410 147.182 134.722 1.00 50.13  ? 271 LEU C O   1 
ATOM   10077 C  CB  . LEU C 2 271 ? 165.808 147.467 132.526 1.00 50.13  ? 271 LEU C CB  1 
ATOM   10078 C  CG  . LEU C 2 271 ? 164.631 147.958 131.692 1.00 50.13  ? 271 LEU C CG  1 
ATOM   10079 C  CD1 . LEU C 2 271 ? 163.790 146.795 131.261 1.00 50.13  ? 271 LEU C CD1 1 
ATOM   10080 C  CD2 . LEU C 2 271 ? 163.806 148.914 132.507 1.00 50.13  ? 271 LEU C CD2 1 
ATOM   10081 N  N   . GLY C 2 272 ? 169.150 148.235 133.770 1.00 51.28  ? 272 GLY C N   1 
ATOM   10082 C  CA  . GLY C 2 272 ? 170.098 147.655 134.692 1.00 51.28  ? 272 GLY C CA  1 
ATOM   10083 C  C   . GLY C 2 272 ? 170.262 148.476 135.954 1.00 51.28  ? 272 GLY C C   1 
ATOM   10084 O  O   . GLY C 2 272 ? 169.541 149.441 136.212 1.00 51.28  ? 272 GLY C O   1 
ATOM   10085 N  N   . CYS C 2 273 ? 171.247 148.076 136.755 1.00 48.81  ? 273 CYS C N   1 
ATOM   10086 C  CA  . CYS C 2 273 ? 171.528 148.731 138.022 1.00 48.81  ? 273 CYS C CA  1 
ATOM   10087 C  C   . CYS C 2 273 ? 172.894 148.379 138.593 1.00 48.81  ? 273 CYS C C   1 
ATOM   10088 O  O   . CYS C 2 273 ? 173.390 149.121 139.446 1.00 48.81  ? 273 CYS C O   1 
ATOM   10089 C  CB  . CYS C 2 273 ? 170.442 148.383 139.053 1.00 48.81  ? 273 CYS C CB  1 
ATOM   10090 S  SG  . CYS C 2 273 ? 170.549 149.262 140.616 1.00 48.81  ? 273 CYS C SG  1 
ATOM   10091 N  N   . PHE C 2 274 ? 173.515 147.286 138.155 1.00 46.59  ? 274 PHE C N   1 
ATOM   10092 C  CA  . PHE C 2 274 ? 174.868 146.956 138.569 1.00 46.59  ? 274 PHE C CA  1 
ATOM   10093 C  C   . PHE C 2 274 ? 175.882 147.743 137.744 1.00 46.59  ? 274 PHE C C   1 
ATOM   10094 O  O   . PHE C 2 274 ? 175.558 148.729 137.078 1.00 46.59  ? 274 PHE C O   1 
ATOM   10095 C  CB  . PHE C 2 274 ? 175.124 145.457 138.443 1.00 46.59  ? 274 PHE C CB  1 
ATOM   10096 C  CG  . PHE C 2 274 ? 174.448 144.629 139.499 1.00 46.59  ? 274 PHE C CG  1 
ATOM   10097 C  CD1 . PHE C 2 274 ? 173.864 145.223 140.605 1.00 46.59  ? 274 PHE C CD1 1 
ATOM   10098 C  CD2 . PHE C 2 274 ? 174.434 143.250 139.403 1.00 46.59  ? 274 PHE C CD2 1 
ATOM   10099 C  CE1 . PHE C 2 274 ? 173.255 144.458 141.581 1.00 46.59  ? 274 PHE C CE1 1 
ATOM   10100 C  CE2 . PHE C 2 274 ? 173.830 142.481 140.376 1.00 46.59  ? 274 PHE C CE2 1 
ATOM   10101 C  CZ  . PHE C 2 274 ? 173.240 143.087 141.467 1.00 46.59  ? 274 PHE C CZ  1 
ATOM   10102 N  N   . ASN C 2 275 ? 177.134 147.291 137.784 1.00 52.67  ? 275 ASN C N   1 
ATOM   10103 C  CA  . ASN C 2 275 ? 178.243 147.979 137.132 1.00 52.67  ? 275 ASN C CA  1 
ATOM   10104 C  C   . ASN C 2 275 ? 179.305 146.975 136.710 1.00 52.67  ? 275 ASN C C   1 
ATOM   10105 O  O   . ASN C 2 275 ? 180.508 147.237 136.796 1.00 52.67  ? 275 ASN C O   1 
ATOM   10106 C  CB  . ASN C 2 275 ? 178.838 149.047 138.050 1.00 52.67  ? 275 ASN C CB  1 
ATOM   10107 C  CG  . ASN C 2 275 ? 179.790 149.981 137.330 1.00 52.67  ? 275 ASN C CG  1 
ATOM   10108 O  OD1 . ASN C 2 275 ? 180.005 149.863 136.126 1.00 52.67  ? 275 ASN C OD1 1 
ATOM   10109 N  ND2 . ASN C 2 275 ? 180.381 150.906 138.074 1.00 52.67  ? 275 ASN C ND2 1 
ATOM   10110 N  N   . LEU C 2 276 ? 178.874 145.807 136.251 1.00 48.01  ? 276 LEU C N   1 
ATOM   10111 C  CA  . LEU C 2 276 ? 179.814 144.782 135.836 1.00 48.01  ? 276 LEU C CA  1 
ATOM   10112 C  C   . LEU C 2 276 ? 180.409 145.113 134.472 1.00 48.01  ? 276 LEU C C   1 
ATOM   10113 O  O   . LEU C 2 276 ? 180.163 146.173 133.891 1.00 48.01  ? 276 LEU C O   1 
ATOM   10114 C  CB  . LEU C 2 276 ? 179.136 143.413 135.789 1.00 48.01  ? 276 LEU C CB  1 
ATOM   10115 C  CG  . LEU C 2 276 ? 178.725 142.805 137.126 1.00 48.01  ? 276 LEU C CG  1 
ATOM   10116 C  CD1 . LEU C 2 276 ? 177.921 141.547 136.906 1.00 48.01  ? 276 LEU C CD1 1 
ATOM   10117 C  CD2 . LEU C 2 276 ? 179.953 142.501 137.943 1.00 48.01  ? 276 LEU C CD2 1 
ATOM   10118 N  N   . THR C 2 277 ? 181.209 144.183 133.972 1.00 54.00  ? 277 THR C N   1 
ATOM   10119 C  CA  . THR C 2 277 ? 181.765 144.231 132.630 1.00 54.00  ? 277 THR C CA  1 
ATOM   10120 C  C   . THR C 2 277 ? 181.673 142.846 132.000 1.00 54.00  ? 277 THR C C   1 
ATOM   10121 O  O   . THR C 2 277 ? 181.231 141.881 132.627 1.00 54.00  ? 277 THR C O   1 
ATOM   10122 C  CB  . THR C 2 277 ? 183.213 144.729 132.658 1.00 54.00  ? 277 THR C CB  1 
ATOM   10123 O  OG1 . THR C 2 277 ? 183.691 144.893 131.318 1.00 54.00  ? 277 THR C OG1 1 
ATOM   10124 C  CG2 . THR C 2 277 ? 184.104 143.748 133.400 1.00 54.00  ? 277 THR C CG2 1 
ATOM   10125 N  N   . ILE C 2 278 ? 182.093 142.754 130.738 1.00 55.00  ? 278 ILE C N   1 
ATOM   10126 C  CA  . ILE C 2 278 ? 181.979 141.490 130.016 1.00 55.00  ? 278 ILE C CA  1 
ATOM   10127 C  C   . ILE C 2 278 ? 182.940 140.452 130.587 1.00 55.00  ? 278 ILE C C   1 
ATOM   10128 O  O   . ILE C 2 278 ? 182.595 139.268 130.718 1.00 55.00  ? 278 ILE C O   1 
ATOM   10129 C  CB  . ILE C 2 278 ? 182.208 141.718 128.512 1.00 55.00  ? 278 ILE C CB  1 
ATOM   10130 C  CG1 . ILE C 2 278 ? 181.093 142.592 127.938 1.00 55.00  ? 278 ILE C CG1 1 
ATOM   10131 C  CG2 . ILE C 2 278 ? 182.287 140.397 127.773 1.00 55.00  ? 278 ILE C CG2 1 
ATOM   10132 C  CD1 . ILE C 2 278 ? 181.344 143.053 126.529 1.00 55.00  ? 278 ILE C CD1 1 
ATOM   10133 N  N   . LYS C 2 279 ? 184.150 140.877 130.957 1.00 56.65  ? 279 LYS C N   1 
ATOM   10134 C  CA  . LYS C 2 279 ? 185.139 139.934 131.466 1.00 56.65  ? 279 LYS C CA  1 
ATOM   10135 C  C   . LYS C 2 279 ? 184.741 139.388 132.833 1.00 56.65  ? 279 LYS C C   1 
ATOM   10136 O  O   . LYS C 2 279 ? 185.214 138.318 133.233 1.00 56.65  ? 279 LYS C O   1 
ATOM   10137 C  CB  . LYS C 2 279 ? 186.513 140.604 131.516 1.00 56.65  ? 279 LYS C CB  1 
ATOM   10138 C  CG  . LYS C 2 279 ? 187.662 139.686 131.895 1.00 56.65  ? 279 LYS C CG  1 
ATOM   10139 C  CD  . LYS C 2 279 ? 189.004 140.384 131.720 1.00 56.65  ? 279 LYS C CD  1 
ATOM   10140 C  CE  . LYS C 2 279 ? 189.219 141.454 132.777 1.00 56.65  ? 279 LYS C CE  1 
ATOM   10141 N  NZ  . LYS C 2 279 ? 189.410 140.863 134.130 1.00 56.65  ? 279 LYS C NZ  1 
ATOM   10142 N  N   . GLY C 2 280 ? 183.865 140.091 133.553 1.00 53.92  ? 280 GLY C N   1 
ATOM   10143 C  CA  . GLY C 2 280 ? 183.344 139.548 134.798 1.00 53.92  ? 280 GLY C CA  1 
ATOM   10144 C  C   . GLY C 2 280 ? 182.441 138.348 134.579 1.00 53.92  ? 280 GLY C C   1 
ATOM   10145 O  O   . GLY C 2 280 ? 182.647 137.288 135.178 1.00 53.92  ? 280 GLY C O   1 
ATOM   10146 N  N   . HIS C 2 281 ? 181.428 138.496 133.720 1.00 52.22  ? 281 HIS C N   1 
ATOM   10147 C  CA  . HIS C 2 281 ? 180.608 137.348 133.343 1.00 52.22  ? 281 HIS C CA  1 
ATOM   10148 C  C   . HIS C 2 281 ? 181.456 136.242 132.734 1.00 52.22  ? 281 HIS C C   1 
ATOM   10149 O  O   . HIS C 2 281 ? 181.163 135.054 132.913 1.00 52.22  ? 281 HIS C O   1 
ATOM   10150 C  CB  . HIS C 2 281 ? 179.517 137.774 132.364 1.00 52.22  ? 281 HIS C CB  1 
ATOM   10151 C  CG  . HIS C 2 281 ? 178.433 138.594 132.982 1.00 52.22  ? 281 HIS C CG  1 
ATOM   10152 N  ND1 . HIS C 2 281 ? 177.388 138.039 133.687 1.00 52.22  ? 281 HIS C ND1 1 
ATOM   10153 C  CD2 . HIS C 2 281 ? 178.242 139.933 133.017 1.00 52.22  ? 281 HIS C CD2 1 
ATOM   10154 C  CE1 . HIS C 2 281 ? 176.590 139.001 134.116 1.00 52.22  ? 281 HIS C CE1 1 
ATOM   10155 N  NE2 . HIS C 2 281 ? 177.087 140.159 133.724 1.00 52.22  ? 281 HIS C NE2 1 
ATOM   10156 N  N   . ALA C 2 282 ? 182.512 136.612 132.006 1.00 51.06  ? 282 ALA C N   1 
ATOM   10157 C  CA  . ALA C 2 282 ? 183.412 135.602 131.463 1.00 51.06  ? 282 ALA C CA  1 
ATOM   10158 C  C   . ALA C 2 282 ? 184.107 134.824 132.571 1.00 51.06  ? 282 ALA C C   1 
ATOM   10159 O  O   . ALA C 2 282 ? 184.277 133.603 132.470 1.00 51.06  ? 282 ALA C O   1 
ATOM   10160 C  CB  . ALA C 2 282 ? 184.441 136.255 130.553 1.00 51.06  ? 282 ALA C CB  1 
ATOM   10161 N  N   . LYS C 2 283 ? 184.540 135.513 133.628 1.00 53.77  ? 283 LYS C N   1 
ATOM   10162 C  CA  . LYS C 2 283 ? 185.169 134.810 134.741 1.00 53.77  ? 283 LYS C CA  1 
ATOM   10163 C  C   . LYS C 2 283 ? 184.158 133.950 135.486 1.00 53.77  ? 283 LYS C C   1 
ATOM   10164 O  O   . LYS C 2 283 ? 184.509 132.894 136.025 1.00 53.77  ? 283 LYS C O   1 
ATOM   10165 C  CB  . LYS C 2 283 ? 185.837 135.805 135.690 1.00 53.77  ? 283 LYS C CB  1 
ATOM   10166 C  CG  . LYS C 2 283 ? 187.046 136.503 135.096 1.00 53.77  ? 283 LYS C CG  1 
ATOM   10167 C  CD  . LYS C 2 283 ? 187.748 137.368 136.124 1.00 53.77  ? 283 LYS C CD  1 
ATOM   10168 C  CE  . LYS C 2 283 ? 186.966 138.640 136.402 1.00 53.77  ? 283 LYS C CE  1 
ATOM   10169 N  NZ  . LYS C 2 283 ? 187.693 139.552 137.328 1.00 53.77  ? 283 LYS C NZ  1 
ATOM   10170 N  N   . CYS C 2 284 ? 182.896 134.380 135.520 1.00 50.88  ? 284 CYS C N   1 
ATOM   10171 C  CA  . CYS C 2 284 ? 181.859 133.575 136.159 1.00 50.88  ? 284 CYS C CA  1 
ATOM   10172 C  C   . CYS C 2 284 ? 181.619 132.280 135.392 1.00 50.88  ? 284 CYS C C   1 
ATOM   10173 O  O   . CYS C 2 284 ? 181.641 131.185 135.970 1.00 50.88  ? 284 CYS C O   1 
ATOM   10174 C  CB  . CYS C 2 284 ? 180.567 134.381 136.264 1.00 50.88  ? 284 CYS C CB  1 
ATOM   10175 S  SG  . CYS C 2 284 ? 180.655 135.805 137.350 1.00 50.88  ? 284 CYS C SG  1 
ATOM   10176 N  N   . VAL C 2 285 ? 181.406 132.385 134.079 1.00 49.16  ? 285 VAL C N   1 
ATOM   10177 C  CA  . VAL C 2 285 ? 181.150 131.194 133.276 1.00 49.16  ? 285 VAL C CA  1 
ATOM   10178 C  C   . VAL C 2 285 ? 182.393 130.319 133.181 1.00 49.16  ? 285 VAL C C   1 
ATOM   10179 O  O   . VAL C 2 285 ? 182.290 129.106 132.967 1.00 49.16  ? 285 VAL C O   1 
ATOM   10180 C  CB  . VAL C 2 285 ? 180.635 131.593 131.882 1.00 49.16  ? 285 VAL C CB  1 
ATOM   10181 C  CG1 . VAL C 2 285 ? 181.727 132.282 131.098 1.00 49.16  ? 285 VAL C CG1 1 
ATOM   10182 C  CG2 . VAL C 2 285 ? 180.125 130.382 131.133 1.00 49.16  ? 285 VAL C CG2 1 
ATOM   10183 N  N   . GLU C 2 286 ? 183.583 130.901 133.337 1.00 53.56  ? 286 GLU C N   1 
ATOM   10184 C  CA  . GLU C 2 286 ? 184.787 130.080 133.330 1.00 53.56  ? 286 GLU C CA  1 
ATOM   10185 C  C   . GLU C 2 286 ? 184.937 129.325 134.644 1.00 53.56  ? 286 GLU C C   1 
ATOM   10186 O  O   . GLU C 2 286 ? 185.314 128.146 134.652 1.00 53.56  ? 286 GLU C O   1 
ATOM   10187 C  CB  . GLU C 2 286 ? 186.014 130.946 133.053 1.00 53.56  ? 286 GLU C CB  1 
ATOM   10188 C  CG  . GLU C 2 286 ? 187.259 130.162 132.669 1.00 53.56  ? 286 GLU C CG  1 
ATOM   10189 C  CD  . GLU C 2 286 ? 188.027 129.653 133.866 1.00 53.56  ? 286 GLU C CD  1 
ATOM   10190 O  OE1 . GLU C 2 286 ? 187.969 130.307 134.928 1.00 53.56  ? 286 GLU C OE1 1 
ATOM   10191 O  OE2 . GLU C 2 286 ? 188.683 128.596 133.746 1.00 53.56  ? 286 GLU C OE2 1 
ATOM   10192 N  N   . PHE C 2 287 ? 184.641 129.983 135.767 1.00 51.68  ? 287 PHE C N   1 
ATOM   10193 C  CA  . PHE C 2 287 ? 184.678 129.290 137.050 1.00 51.68  ? 287 PHE C CA  1 
ATOM   10194 C  C   . PHE C 2 287 ? 183.652 128.166 137.101 1.00 51.68  ? 287 PHE C C   1 
ATOM   10195 O  O   . PHE C 2 287 ? 183.972 127.044 137.508 1.00 51.68  ? 287 PHE C O   1 
ATOM   10196 C  CB  . PHE C 2 287 ? 184.444 130.276 138.191 1.00 51.68  ? 287 PHE C CB  1 
ATOM   10197 C  CG  . PHE C 2 287 ? 184.472 129.643 139.545 1.00 51.68  ? 287 PHE C CG  1 
ATOM   10198 C  CD1 . PHE C 2 287 ? 185.669 129.241 140.109 1.00 51.68  ? 287 PHE C CD1 1 
ATOM   10199 C  CD2 . PHE C 2 287 ? 183.306 129.454 140.258 1.00 51.68  ? 287 PHE C CD2 1 
ATOM   10200 C  CE1 . PHE C 2 287 ? 185.702 128.655 141.357 1.00 51.68  ? 287 PHE C CE1 1 
ATOM   10201 C  CE2 . PHE C 2 287 ? 183.333 128.871 141.508 1.00 51.68  ? 287 PHE C CE2 1 
ATOM   10202 C  CZ  . PHE C 2 287 ? 184.534 128.471 142.058 1.00 51.68  ? 287 PHE C CZ  1 
ATOM   10203 N  N   . VAL C 2 288 ? 182.411 128.446 136.696 1.00 48.87  ? 288 VAL C N   1 
ATOM   10204 C  CA  . VAL C 2 288 ? 181.399 127.395 136.665 1.00 48.87  ? 288 VAL C CA  1 
ATOM   10205 C  C   . VAL C 2 288 ? 181.787 126.314 135.664 1.00 48.87  ? 288 VAL C C   1 
ATOM   10206 O  O   . VAL C 2 288 ? 181.517 125.126 135.875 1.00 48.87  ? 288 VAL C O   1 
ATOM   10207 C  CB  . VAL C 2 288 ? 180.016 127.994 136.353 1.00 48.87  ? 288 VAL C CB  1 
ATOM   10208 C  CG1 . VAL C 2 288 ? 178.977 126.900 136.210 1.00 48.87  ? 288 VAL C CG1 1 
ATOM   10209 C  CG2 . VAL C 2 288 ? 179.611 128.958 137.445 1.00 48.87  ? 288 VAL C CG2 1 
ATOM   10210 N  N   . LYS C 2 289 ? 182.448 126.703 134.573 1.00 52.54  ? 289 LYS C N   1 
ATOM   10211 C  CA  . LYS C 2 289 ? 182.837 125.733 133.556 1.00 52.54  ? 289 LYS C CA  1 
ATOM   10212 C  C   . LYS C 2 289 ? 183.988 124.856 134.032 1.00 52.54  ? 289 LYS C C   1 
ATOM   10213 O  O   . LYS C 2 289 ? 184.197 123.763 133.493 1.00 52.54  ? 289 LYS C O   1 
ATOM   10214 C  CB  . LYS C 2 289 ? 183.199 126.465 132.260 1.00 52.54  ? 289 LYS C CB  1 
ATOM   10215 C  CG  . LYS C 2 289 ? 183.505 125.573 131.065 1.00 52.54  ? 289 LYS C CG  1 
ATOM   10216 C  CD  . LYS C 2 289 ? 184.998 125.371 130.868 1.00 52.54  ? 289 LYS C CD  1 
ATOM   10217 C  CE  . LYS C 2 289 ? 185.662 126.634 130.356 1.00 52.54  ? 289 LYS C CE  1 
ATOM   10218 N  NZ  . LYS C 2 289 ? 187.120 126.433 130.148 1.00 52.54  ? 289 LYS C NZ  1 
ATOM   10219 N  N   . SER C 2 290 ? 184.726 125.297 135.053 1.00 54.12  ? 290 SER C N   1 
ATOM   10220 C  CA  . SER C 2 290 ? 185.919 124.573 135.477 1.00 54.12  ? 290 SER C CA  1 
ATOM   10221 C  C   . SER C 2 290 ? 185.633 123.454 136.472 1.00 54.12  ? 290 SER C C   1 
ATOM   10222 O  O   . SER C 2 290 ? 186.557 123.041 137.180 1.00 54.12  ? 290 SER C O   1 
ATOM   10223 C  CB  . SER C 2 290 ? 186.932 125.542 136.086 1.00 54.12  ? 290 SER C CB  1 
ATOM   10224 O  OG  . SER C 2 290 ? 186.451 126.088 137.301 1.00 54.12  ? 290 SER C OG  1 
ATOM   10225 N  N   . PHE C 2 291 ? 184.403 122.950 136.549 1.00 55.71  ? 291 PHE C N   1 
ATOM   10226 C  CA  . PHE C 2 291 ? 184.113 121.841 137.451 1.00 55.71  ? 291 PHE C CA  1 
ATOM   10227 C  C   . PHE C 2 291 ? 183.920 120.513 136.732 1.00 55.71  ? 291 PHE C C   1 
ATOM   10228 O  O   . PHE C 2 291 ? 183.718 119.495 137.403 1.00 55.71  ? 291 PHE C O   1 
ATOM   10229 C  CB  . PHE C 2 291 ? 182.875 122.142 138.300 1.00 55.71  ? 291 PHE C CB  1 
ATOM   10230 C  CG  . PHE C 2 291 ? 183.095 123.203 139.337 1.00 55.71  ? 291 PHE C CG  1 
ATOM   10231 C  CD1 . PHE C 2 291 ? 183.786 122.915 140.501 1.00 55.71  ? 291 PHE C CD1 1 
ATOM   10232 C  CD2 . PHE C 2 291 ? 182.594 124.479 139.163 1.00 55.71  ? 291 PHE C CD2 1 
ATOM   10233 C  CE1 . PHE C 2 291 ? 183.988 123.883 141.461 1.00 55.71  ? 291 PHE C CE1 1 
ATOM   10234 C  CE2 . PHE C 2 291 ? 182.792 125.450 140.122 1.00 55.71  ? 291 PHE C CE2 1 
ATOM   10235 C  CZ  . PHE C 2 291 ? 183.490 125.151 141.270 1.00 55.71  ? 291 PHE C CZ  1 
ATOM   10236 N  N   . ASN C 2 292 ? 183.972 120.499 135.400 1.00 57.86  ? 292 ASN C N   1 
ATOM   10237 C  CA  . ASN C 2 292 ? 183.852 119.279 134.600 1.00 57.86  ? 292 ASN C CA  1 
ATOM   10238 C  C   . ASN C 2 292 ? 182.514 118.580 134.854 1.00 57.86  ? 292 ASN C C   1 
ATOM   10239 O  O   . ASN C 2 292 ? 182.451 117.402 135.211 1.00 57.86  ? 292 ASN C O   1 
ATOM   10240 C  CB  . ASN C 2 292 ? 185.029 118.334 134.864 1.00 57.86  ? 292 ASN C CB  1 
ATOM   10241 C  CG  . ASN C 2 292 ? 186.340 118.870 134.327 1.00 57.86  ? 292 ASN C CG  1 
ATOM   10242 O  OD1 . ASN C 2 292 ? 186.396 119.420 133.227 1.00 57.86  ? 292 ASN C OD1 1 
ATOM   10243 N  ND2 . ASN C 2 292 ? 187.408 118.710 135.101 1.00 57.86  ? 292 ASN C ND2 1 
ATOM   10244 N  N   . LEU C 2 293 ? 181.437 119.333 134.656 1.00 50.22  ? 293 LEU C N   1 
ATOM   10245 C  CA  . LEU C 2 293 ? 180.080 118.834 134.803 1.00 50.22  ? 293 LEU C CA  1 
ATOM   10246 C  C   . LEU C 2 293 ? 179.273 119.162 133.557 1.00 50.22  ? 293 LEU C C   1 
ATOM   10247 O  O   . LEU C 2 293 ? 179.552 120.156 132.879 1.00 50.22  ? 293 LEU C O   1 
ATOM   10248 C  CB  . LEU C 2 293 ? 179.387 119.447 136.029 1.00 50.22  ? 293 LEU C CB  1 
ATOM   10249 C  CG  . LEU C 2 293 ? 179.910 119.062 137.411 1.00 50.22  ? 293 LEU C CG  1 
ATOM   10250 C  CD1 . LEU C 2 293 ? 179.216 119.877 138.482 1.00 50.22  ? 293 LEU C CD1 1 
ATOM   10251 C  CD2 . LEU C 2 293 ? 179.711 117.581 137.660 1.00 50.22  ? 293 LEU C CD2 1 
ATOM   10252 N  N   . PRO C 2 294 ? 178.277 118.334 133.221 1.00 47.16  ? 294 PRO C N   1 
ATOM   10253 C  CA  . PRO C 2 294 ? 177.374 118.680 132.115 1.00 47.16  ? 294 PRO C CA  1 
ATOM   10254 C  C   . PRO C 2 294 ? 176.722 120.036 132.329 1.00 47.16  ? 294 PRO C C   1 
ATOM   10255 O  O   . PRO C 2 294 ? 175.860 120.199 133.199 1.00 47.16  ? 294 PRO C O   1 
ATOM   10256 C  CB  . PRO C 2 294 ? 176.348 117.542 132.132 1.00 47.16  ? 294 PRO C CB  1 
ATOM   10257 C  CG  . PRO C 2 294 ? 177.078 116.401 132.734 1.00 47.16  ? 294 PRO C CG  1 
ATOM   10258 C  CD  . PRO C 2 294 ? 177.985 117.000 133.769 1.00 47.16  ? 294 PRO C CD  1 
ATOM   10259 N  N   . MET C 2 295 ? 177.140 121.017 131.537 1.00 41.64  ? 295 MET C N   1 
ATOM   10260 C  CA  . MET C 2 295 ? 176.774 122.411 131.733 1.00 41.64  ? 295 MET C CA  1 
ATOM   10261 C  C   . MET C 2 295 ? 175.787 122.837 130.657 1.00 41.64  ? 295 MET C C   1 
ATOM   10262 O  O   . MET C 2 295 ? 175.904 122.418 129.503 1.00 41.64  ? 295 MET C O   1 
ATOM   10263 C  CB  . MET C 2 295 ? 178.022 123.291 131.691 1.00 41.64  ? 295 MET C CB  1 
ATOM   10264 C  CG  . MET C 2 295 ? 177.791 124.740 132.023 1.00 41.64  ? 295 MET C CG  1 
ATOM   10265 S  SD  . MET C 2 295 ? 179.337 125.652 132.022 1.00 41.64  ? 295 MET C SD  1 
ATOM   10266 C  CE  . MET C 2 295 ? 178.735 127.285 132.402 1.00 41.64  ? 295 MET C CE  1 
ATOM   10267 N  N   . LEU C 2 296 ? 174.821 123.669 131.037 1.00 37.36  ? 296 LEU C N   1 
ATOM   10268 C  CA  . LEU C 2 296 ? 173.786 124.159 130.134 1.00 37.36  ? 296 LEU C CA  1 
ATOM   10269 C  C   . LEU C 2 296 ? 173.664 125.667 130.285 1.00 37.36  ? 296 LEU C C   1 
ATOM   10270 O  O   . LEU C 2 296 ? 173.091 126.148 131.267 1.00 37.36  ? 296 LEU C O   1 
ATOM   10271 C  CB  . LEU C 2 296 ? 172.445 123.482 130.427 1.00 37.36  ? 296 LEU C CB  1 
ATOM   10272 C  CG  . LEU C 2 296 ? 171.231 123.962 129.632 1.00 37.36  ? 296 LEU C CG  1 
ATOM   10273 C  CD1 . LEU C 2 296 ? 171.423 123.714 128.162 1.00 37.36  ? 296 LEU C CD1 1 
ATOM   10274 C  CD2 . LEU C 2 296 ? 169.965 123.287 130.129 1.00 37.36  ? 296 LEU C CD2 1 
ATOM   10275 N  N   . MET C 2 297 ? 174.194 126.408 129.318 1.00 39.42  ? 297 MET C N   1 
ATOM   10276 C  CA  . MET C 2 297 ? 174.119 127.861 129.326 1.00 39.42  ? 297 MET C CA  1 
ATOM   10277 C  C   . MET C 2 297 ? 172.856 128.338 128.626 1.00 39.42  ? 297 MET C C   1 
ATOM   10278 O  O   . MET C 2 297 ? 172.542 127.900 127.517 1.00 39.42  ? 297 MET C O   1 
ATOM   10279 C  CB  . MET C 2 297 ? 175.333 128.491 128.651 1.00 39.42  ? 297 MET C CB  1 
ATOM   10280 C  CG  . MET C 2 297 ? 176.616 128.351 129.424 1.00 39.42  ? 297 MET C CG  1 
ATOM   10281 S  SD  . MET C 2 297 ? 177.928 129.282 128.629 1.00 39.42  ? 297 MET C SD  1 
ATOM   10282 C  CE  . MET C 2 297 ? 178.211 128.243 127.215 1.00 39.42  ? 297 MET C CE  1 
ATOM   10283 N  N   . LEU C 2 298 ? 172.149 129.255 129.276 1.00 38.37  ? 298 LEU C N   1 
ATOM   10284 C  CA  . LEU C 2 298 ? 170.925 129.820 128.742 1.00 38.37  ? 298 LEU C CA  1 
ATOM   10285 C  C   . LEU C 2 298 ? 171.090 131.328 128.612 1.00 38.37  ? 298 LEU C C   1 
ATOM   10286 O  O   . LEU C 2 298 ? 172.182 131.870 128.795 1.00 38.37  ? 298 LEU C O   1 
ATOM   10287 C  CB  . LEU C 2 298 ? 169.731 129.469 129.633 1.00 38.37  ? 298 LEU C CB  1 
ATOM   10288 C  CG  . LEU C 2 298 ? 169.441 127.968 129.683 1.00 38.37  ? 298 LEU C CG  1 
ATOM   10289 C  CD1 . LEU C 2 298 ? 168.408 127.648 130.735 1.00 38.37  ? 298 LEU C CD1 1 
ATOM   10290 C  CD2 . LEU C 2 298 ? 168.986 127.469 128.322 1.00 38.37  ? 298 LEU C CD2 1 
ATOM   10291 N  N   . GLY C 2 299 ? 169.995 132.004 128.288 1.00 39.05  ? 299 GLY C N   1 
ATOM   10292 C  CA  . GLY C 2 299 ? 170.044 133.439 128.097 1.00 39.05  ? 299 GLY C CA  1 
ATOM   10293 C  C   . GLY C 2 299 ? 169.124 134.188 129.035 1.00 39.05  ? 299 GLY C C   1 
ATOM   10294 O  O   . GLY C 2 299 ? 169.235 134.059 130.256 1.00 39.05  ? 299 GLY C O   1 
ATOM   10295 N  N   . GLY C 2 300 ? 168.210 134.976 128.477 1.00 42.33  ? 300 GLY C N   1 
ATOM   10296 C  CA  . GLY C 2 300 ? 167.253 135.703 129.287 1.00 42.33  ? 300 GLY C CA  1 
ATOM   10297 C  C   . GLY C 2 300 ? 167.851 136.909 129.975 1.00 42.33  ? 300 GLY C C   1 
ATOM   10298 O  O   . GLY C 2 300 ? 168.841 136.791 130.701 1.00 42.33  ? 300 GLY C O   1 
ATOM   10299 N  N   . GLY C 2 301 ? 167.257 138.076 129.757 1.00 44.82  ? 301 GLY C N   1 
ATOM   10300 C  CA  . GLY C 2 301 ? 167.770 139.305 130.317 1.00 44.82  ? 301 GLY C CA  1 
ATOM   10301 C  C   . GLY C 2 301 ? 168.792 139.966 129.413 1.00 44.82  ? 301 GLY C C   1 
ATOM   10302 O  O   . GLY C 2 301 ? 169.623 139.324 128.773 1.00 44.82  ? 301 GLY C O   1 
ATOM   10303 N  N   . GLY C 2 302 ? 168.716 141.290 129.362 1.00 47.86  ? 302 GLY C N   1 
ATOM   10304 C  CA  . GLY C 2 302 ? 169.634 142.073 128.563 1.00 47.86  ? 302 GLY C CA  1 
ATOM   10305 C  C   . GLY C 2 302 ? 168.905 142.970 127.589 1.00 47.86  ? 302 GLY C C   1 
ATOM   10306 O  O   . GLY C 2 302 ? 168.351 142.488 126.596 1.00 47.86  ? 302 GLY C O   1 
ATOM   10307 N  N   . TYR C 2 303 ? 168.897 144.279 127.847 1.00 50.25  ? 303 TYR C N   1 
ATOM   10308 C  CA  . TYR C 2 303 ? 168.033 145.174 127.098 1.00 50.25  ? 303 TYR C CA  1 
ATOM   10309 C  C   . TYR C 2 303 ? 168.761 146.290 126.362 1.00 50.25  ? 303 TYR C C   1 
ATOM   10310 O  O   . TYR C 2 303 ? 168.103 147.055 125.650 1.00 50.25  ? 303 TYR C O   1 
ATOM   10311 C  CB  . TYR C 2 303 ? 166.971 145.778 128.027 1.00 50.25  ? 303 TYR C CB  1 
ATOM   10312 C  CG  . TYR C 2 303 ? 166.174 144.707 128.739 1.00 50.25  ? 303 TYR C CG  1 
ATOM   10313 C  CD1 . TYR C 2 303 ? 165.267 143.916 128.052 1.00 50.25  ? 303 TYR C CD1 1 
ATOM   10314 C  CD2 . TYR C 2 303 ? 166.323 144.496 130.098 1.00 50.25  ? 303 TYR C CD2 1 
ATOM   10315 C  CE1 . TYR C 2 303 ? 164.547 142.932 128.698 1.00 50.25  ? 303 TYR C CE1 1 
ATOM   10316 C  CE2 . TYR C 2 303 ? 165.605 143.518 130.751 1.00 50.25  ? 303 TYR C CE2 1 
ATOM   10317 C  CZ  . TYR C 2 303 ? 164.718 142.741 130.046 1.00 50.25  ? 303 TYR C CZ  1 
ATOM   10318 O  OH  . TYR C 2 303 ? 163.998 141.766 130.689 1.00 50.25  ? 303 TYR C OH  1 
ATOM   10319 N  N   . THR C 2 304 ? 170.079 146.414 126.508 1.00 50.36  ? 304 THR C N   1 
ATOM   10320 C  CA  . THR C 2 304 ? 170.902 147.195 125.589 1.00 50.36  ? 304 THR C CA  1 
ATOM   10321 C  C   . THR C 2 304 ? 171.521 146.207 124.610 1.00 50.36  ? 304 THR C C   1 
ATOM   10322 O  O   . THR C 2 304 ? 172.408 145.432 124.978 1.00 50.36  ? 304 THR C O   1 
ATOM   10323 C  CB  . THR C 2 304 ? 171.975 147.997 126.321 1.00 50.36  ? 304 THR C CB  1 
ATOM   10324 O  OG1 . THR C 2 304 ? 171.351 148.955 127.182 1.00 50.36  ? 304 THR C OG1 1 
ATOM   10325 C  CG2 . THR C 2 304 ? 172.851 148.729 125.329 1.00 50.36  ? 304 THR C CG2 1 
ATOM   10326 N  N   . ILE C 2 305 ? 171.059 146.250 123.360 1.00 51.47  ? 305 ILE C N   1 
ATOM   10327 C  CA  . ILE C 2 305 ? 171.235 145.121 122.452 1.00 51.47  ? 305 ILE C CA  1 
ATOM   10328 C  C   . ILE C 2 305 ? 172.708 144.875 122.140 1.00 51.47  ? 305 ILE C C   1 
ATOM   10329 O  O   . ILE C 2 305 ? 173.175 143.728 122.164 1.00 51.47  ? 305 ILE C O   1 
ATOM   10330 C  CB  . ILE C 2 305 ? 170.408 145.350 121.177 1.00 51.47  ? 305 ILE C CB  1 
ATOM   10331 C  CG1 . ILE C 2 305 ? 168.934 145.501 121.536 1.00 51.47  ? 305 ILE C CG1 1 
ATOM   10332 C  CG2 . ILE C 2 305 ? 170.572 144.200 120.240 1.00 51.47  ? 305 ILE C CG2 1 
ATOM   10333 C  CD1 . ILE C 2 305 ? 168.360 144.292 122.221 1.00 51.47  ? 305 ILE C CD1 1 
ATOM   10334 N  N   . ARG C 2 306 ? 173.465 145.933 121.847 1.00 55.45  ? 306 ARG C N   1 
ATOM   10335 C  CA  . ARG C 2 306 ? 174.857 145.748 121.446 1.00 55.45  ? 306 ARG C CA  1 
ATOM   10336 C  C   . ARG C 2 306 ? 175.681 145.123 122.568 1.00 55.45  ? 306 ARG C C   1 
ATOM   10337 O  O   . ARG C 2 306 ? 176.520 144.245 122.324 1.00 55.45  ? 306 ARG C O   1 
ATOM   10338 C  CB  . ARG C 2 306 ? 175.451 147.084 120.994 1.00 55.45  ? 306 ARG C CB  1 
ATOM   10339 C  CG  . ARG C 2 306 ? 175.522 148.145 122.075 1.00 55.45  ? 306 ARG C CG  1 
ATOM   10340 C  CD  . ARG C 2 306 ? 175.990 149.478 121.524 1.00 55.45  ? 306 ARG C CD  1 
ATOM   10341 N  NE  . ARG C 2 306 ? 176.140 150.471 122.582 1.00 55.45  ? 306 ARG C NE  1 
ATOM   10342 C  CZ  . ARG C 2 306 ? 175.156 151.248 123.022 1.00 55.45  ? 306 ARG C CZ  1 
ATOM   10343 N  NH1 . ARG C 2 306 ? 173.945 151.149 122.495 1.00 55.45  ? 306 ARG C NH1 1 
ATOM   10344 N  NH2 . ARG C 2 306 ? 175.383 152.123 123.991 1.00 55.45  ? 306 ARG C NH2 1 
ATOM   10345 N  N   . ASN C 2 307 ? 175.431 145.538 123.814 1.00 51.30  ? 307 ASN C N   1 
ATOM   10346 C  CA  . ASN C 2 307 ? 176.162 144.970 124.942 1.00 51.30  ? 307 ASN C CA  1 
ATOM   10347 C  C   . ASN C 2 307 ? 175.770 143.522 125.194 1.00 51.30  ? 307 ASN C C   1 
ATOM   10348 O  O   . ASN C 2 307 ? 176.586 142.736 125.688 1.00 51.30  ? 307 ASN C O   1 
ATOM   10349 C  CB  . ASN C 2 307 ? 175.928 145.805 126.198 1.00 51.30  ? 307 ASN C CB  1 
ATOM   10350 C  CG  . ASN C 2 307 ? 176.573 147.169 126.116 1.00 51.30  ? 307 ASN C CG  1 
ATOM   10351 O  OD1 . ASN C 2 307 ? 177.673 147.316 125.590 1.00 51.30  ? 307 ASN C OD1 1 
ATOM   10352 N  ND2 . ASN C 2 307 ? 175.899 148.176 126.652 1.00 51.30  ? 307 ASN C ND2 1 
ATOM   10353 N  N   . VAL C 2 308 ? 174.530 143.153 124.868 1.00 47.07  ? 308 VAL C N   1 
ATOM   10354 C  CA  . VAL C 2 308 ? 174.109 141.763 125.005 1.00 47.07  ? 308 VAL C CA  1 
ATOM   10355 C  C   . VAL C 2 308 ? 174.797 140.899 123.959 1.00 47.07  ? 308 VAL C C   1 
ATOM   10356 O  O   . VAL C 2 308 ? 175.274 139.798 124.254 1.00 47.07  ? 308 VAL C O   1 
ATOM   10357 C  CB  . VAL C 2 308 ? 172.579 141.653 124.905 1.00 47.07  ? 308 VAL C CB  1 
ATOM   10358 C  CG1 . VAL C 2 308 ? 172.148 140.205 124.980 1.00 47.07  ? 308 VAL C CG1 1 
ATOM   10359 C  CG2 . VAL C 2 308 ? 171.934 142.456 126.000 1.00 47.07  ? 308 VAL C CG2 1 
ATOM   10360 N  N   . ALA C 2 309 ? 174.854 141.383 122.715 1.00 49.38  ? 309 ALA C N   1 
ATOM   10361 C  CA  . ALA C 2 309 ? 175.545 140.634 121.671 1.00 49.38  ? 309 ALA C CA  1 
ATOM   10362 C  C   . ALA C 2 309 ? 177.020 140.453 122.006 1.00 49.38  ? 309 ALA C C   1 
ATOM   10363 O  O   . ALA C 2 309 ? 177.560 139.345 121.891 1.00 49.38  ? 309 ALA C O   1 
ATOM   10364 C  CB  . ALA C 2 309 ? 175.383 141.335 120.325 1.00 49.38  ? 309 ALA C CB  1 
ATOM   10365 N  N   . ARG C 2 310 ? 177.685 141.528 122.434 1.00 54.47  ? 310 ARG C N   1 
ATOM   10366 C  CA  . ARG C 2 310 ? 179.086 141.429 122.836 1.00 54.47  ? 310 ARG C CA  1 
ATOM   10367 C  C   . ARG C 2 310 ? 179.260 140.438 123.982 1.00 54.47  ? 310 ARG C C   1 
ATOM   10368 O  O   . ARG C 2 310 ? 180.101 139.529 123.920 1.00 54.47  ? 310 ARG C O   1 
ATOM   10369 C  CB  . ARG C 2 310 ? 179.601 142.808 123.244 1.00 54.47  ? 310 ARG C CB  1 
ATOM   10370 C  CG  . ARG C 2 310 ? 179.663 143.817 122.113 1.00 54.47  ? 310 ARG C CG  1 
ATOM   10371 C  CD  . ARG C 2 310 ? 180.058 145.188 122.632 1.00 54.47  ? 310 ARG C CD  1 
ATOM   10372 N  NE  . ARG C 2 310 ? 180.106 146.184 121.568 1.00 54.47  ? 310 ARG C NE  1 
ATOM   10373 C  CZ  . ARG C 2 310 ? 180.368 147.471 121.763 1.00 54.47  ? 310 ARG C CZ  1 
ATOM   10374 N  NH1 . ARG C 2 310 ? 180.605 147.922 122.985 1.00 54.47  ? 310 ARG C NH1 1 
ATOM   10375 N  NH2 . ARG C 2 310 ? 180.391 148.307 120.735 1.00 54.47  ? 310 ARG C NH2 1 
ATOM   10376 N  N   . CYS C 2 311 ? 178.467 140.605 125.044 1.00 47.92  ? 311 CYS C N   1 
ATOM   10377 C  CA  . CYS C 2 311 ? 178.582 139.736 126.209 1.00 47.92  ? 311 CYS C CA  1 
ATOM   10378 C  C   . CYS C 2 311 ? 178.414 138.276 125.823 1.00 47.92  ? 311 CYS C C   1 
ATOM   10379 O  O   . CYS C 2 311 ? 179.263 137.439 126.141 1.00 47.92  ? 311 CYS C O   1 
ATOM   10380 C  CB  . CYS C 2 311 ? 177.552 140.134 127.266 1.00 47.92  ? 311 CYS C CB  1 
ATOM   10381 S  SG  . CYS C 2 311 ? 177.636 139.166 128.785 1.00 47.92  ? 311 CYS C SG  1 
ATOM   10382 N  N   . TRP C 2 312 ? 177.337 137.957 125.105 1.00 43.00  ? 312 TRP C N   1 
ATOM   10383 C  CA  . TRP C 2 312 ? 177.047 136.563 124.787 1.00 43.00  ? 312 TRP C CA  1 
ATOM   10384 C  C   . TRP C 2 312 ? 178.078 135.970 123.833 1.00 43.00  ? 312 TRP C C   1 
ATOM   10385 O  O   . TRP C 2 312 ? 178.453 134.799 123.975 1.00 43.00  ? 312 TRP C O   1 
ATOM   10386 C  CB  . TRP C 2 312 ? 175.640 136.443 124.209 1.00 43.00  ? 312 TRP C CB  1 
ATOM   10387 C  CG  . TRP C 2 312 ? 174.567 136.632 125.233 1.00 43.00  ? 312 TRP C CG  1 
ATOM   10388 C  CD1 . TRP C 2 312 ? 174.733 136.733 126.580 1.00 43.00  ? 312 TRP C CD1 1 
ATOM   10389 C  CD2 . TRP C 2 312 ? 173.159 136.729 124.994 1.00 43.00  ? 312 TRP C CD2 1 
ATOM   10390 N  NE1 . TRP C 2 312 ? 173.519 136.890 127.197 1.00 43.00  ? 312 TRP C NE1 1 
ATOM   10391 C  CE2 . TRP C 2 312 ? 172.535 136.893 126.245 1.00 43.00  ? 312 TRP C CE2 1 
ATOM   10392 C  CE3 . TRP C 2 312 ? 172.366 136.696 123.846 1.00 43.00  ? 312 TRP C CE3 1 
ATOM   10393 C  CZ2 . TRP C 2 312 ? 171.159 137.023 126.379 1.00 43.00  ? 312 TRP C CZ2 1 
ATOM   10394 C  CZ3 . TRP C 2 312 ? 171.000 136.825 123.982 1.00 43.00  ? 312 TRP C CZ3 1 
ATOM   10395 C  CH2 . TRP C 2 312 ? 170.410 136.987 125.239 1.00 43.00  ? 312 TRP C CH2 1 
ATOM   10396 N  N   . THR C 2 313 ? 178.554 136.749 122.857 1.00 49.68  ? 313 THR C N   1 
ATOM   10397 C  CA  . THR C 2 313 ? 179.555 136.189 121.953 1.00 49.68  ? 313 THR C CA  1 
ATOM   10398 C  C   . THR C 2 313 ? 180.879 135.948 122.669 1.00 49.68  ? 313 THR C C   1 
ATOM   10399 O  O   . THR C 2 313 ? 181.598 134.999 122.330 1.00 49.68  ? 313 THR C O   1 
ATOM   10400 C  CB  . THR C 2 313 ? 179.756 137.081 120.725 1.00 49.68  ? 313 THR C CB  1 
ATOM   10401 O  OG1 . THR C 2 313 ? 180.565 136.389 119.769 1.00 49.68  ? 313 THR C OG1 1 
ATOM   10402 C  CG2 . THR C 2 313 ? 180.448 138.375 121.081 1.00 49.68  ? 313 THR C CG2 1 
ATOM   10403 N  N   . TYR C 2 314 ? 181.207 136.756 123.681 1.00 51.65  ? 314 TYR C N   1 
ATOM   10404 C  CA  . TYR C 2 314 ? 182.415 136.457 124.442 1.00 51.65  ? 314 TYR C CA  1 
ATOM   10405 C  C   . TYR C 2 314 ? 182.176 135.302 125.410 1.00 51.65  ? 314 TYR C C   1 
ATOM   10406 O  O   . TYR C 2 314 ? 183.112 134.573 125.759 1.00 51.65  ? 314 TYR C O   1 
ATOM   10407 C  CB  . TYR C 2 314 ? 182.908 137.703 125.172 1.00 51.65  ? 314 TYR C CB  1 
ATOM   10408 C  CG  . TYR C 2 314 ? 184.271 137.525 125.795 1.00 51.65  ? 314 TYR C CG  1 
ATOM   10409 C  CD1 . TYR C 2 314 ? 185.399 137.381 124.998 1.00 51.65  ? 314 TYR C CD1 1 
ATOM   10410 C  CD2 . TYR C 2 314 ? 184.440 137.534 127.169 1.00 51.65  ? 314 TYR C CD2 1 
ATOM   10411 C  CE1 . TYR C 2 314 ? 186.652 137.223 125.554 1.00 51.65  ? 314 TYR C CE1 1 
ATOM   10412 C  CE2 . TYR C 2 314 ? 185.690 137.387 127.730 1.00 51.65  ? 314 TYR C CE2 1 
ATOM   10413 C  CZ  . TYR C 2 314 ? 186.789 137.228 126.923 1.00 51.65  ? 314 TYR C CZ  1 
ATOM   10414 O  OH  . TYR C 2 314 ? 188.028 137.077 127.499 1.00 51.65  ? 314 TYR C OH  1 
ATOM   10415 N  N   . GLU C 2 315 ? 180.924 135.108 125.835 1.00 49.54  ? 315 GLU C N   1 
ATOM   10416 C  CA  . GLU C 2 315 ? 180.575 133.923 126.612 1.00 49.54  ? 315 GLU C CA  1 
ATOM   10417 C  C   . GLU C 2 315 ? 180.826 132.658 125.811 1.00 49.54  ? 315 GLU C C   1 
ATOM   10418 O  O   . GLU C 2 315 ? 181.484 131.729 126.293 1.00 49.54  ? 315 GLU C O   1 
ATOM   10419 C  CB  . GLU C 2 315 ? 179.111 133.988 127.040 1.00 49.54  ? 315 GLU C CB  1 
ATOM   10420 C  CG  . GLU C 2 315 ? 178.805 135.101 128.006 1.00 49.54  ? 315 GLU C CG  1 
ATOM   10421 C  CD  . GLU C 2 315 ? 179.380 134.844 129.362 1.00 49.54  ? 315 GLU C CD  1 
ATOM   10422 O  OE1 . GLU C 2 315 ? 179.373 133.671 129.777 1.00 49.54  ? 315 GLU C OE1 1 
ATOM   10423 O  OE2 . GLU C 2 315 ? 179.850 135.804 130.003 1.00 49.54  ? 315 GLU C OE2 1 
ATOM   10424 N  N   . THR C 2 316 ? 180.309 132.604 124.581 1.00 48.39  ? 316 THR C N   1 
ATOM   10425 C  CA  . THR C 2 316 ? 180.590 131.462 123.718 1.00 48.39  ? 316 THR C CA  1 
ATOM   10426 C  C   . THR C 2 316 ? 182.078 131.373 123.403 1.00 48.39  ? 316 THR C C   1 
ATOM   10427 O  O   . THR C 2 316 ? 182.606 130.282 123.155 1.00 48.39  ? 316 THR C O   1 
ATOM   10428 C  CB  . THR C 2 316 ? 179.768 131.560 122.434 1.00 48.39  ? 316 THR C CB  1 
ATOM   10429 O  OG1 . THR C 2 316 ? 178.379 131.659 122.765 1.00 48.39  ? 316 THR C OG1 1 
ATOM   10430 C  CG2 . THR C 2 316 ? 179.971 130.329 121.579 1.00 48.39  ? 316 THR C CG2 1 
ATOM   10431 N  N   . ALA C 2 317 ? 182.779 132.510 123.424 1.00 52.28  ? 317 ALA C N   1 
ATOM   10432 C  CA  . ALA C 2 317 ? 184.229 132.472 123.262 1.00 52.28  ? 317 ALA C CA  1 
ATOM   10433 C  C   . ALA C 2 317 ? 184.910 131.872 124.486 1.00 52.28  ? 317 ALA C C   1 
ATOM   10434 O  O   . ALA C 2 317 ? 186.053 131.411 124.399 1.00 52.28  ? 317 ALA C O   1 
ATOM   10435 C  CB  . ALA C 2 317 ? 184.767 133.872 122.986 1.00 52.28  ? 317 ALA C CB  1 
ATOM   10436 N  N   . VAL C 2 318 ? 184.231 131.875 125.636 1.00 52.15  ? 318 VAL C N   1 
ATOM   10437 C  CA  . VAL C 2 318 ? 184.800 131.253 126.831 1.00 52.15  ? 318 VAL C CA  1 
ATOM   10438 C  C   . VAL C 2 318 ? 184.445 129.772 126.887 1.00 52.15  ? 318 VAL C C   1 
ATOM   10439 O  O   . VAL C 2 318 ? 185.254 128.944 127.323 1.00 52.15  ? 318 VAL C O   1 
ATOM   10440 C  CB  . VAL C 2 318 ? 184.335 131.995 128.097 1.00 52.15  ? 318 VAL C CB  1 
ATOM   10441 C  CG1 . VAL C 2 318 ? 184.781 131.255 129.343 1.00 52.15  ? 318 VAL C CG1 1 
ATOM   10442 C  CG2 . VAL C 2 318 ? 184.889 133.401 128.112 1.00 52.15  ? 318 VAL C CG2 1 
ATOM   10443 N  N   . ALA C 2 319 ? 183.235 129.414 126.447 1.00 55.35  ? 319 ALA C N   1 
ATOM   10444 C  CA  . ALA C 2 319 ? 182.809 128.019 126.488 1.00 55.35  ? 319 ALA C CA  1 
ATOM   10445 C  C   . ALA C 2 319 ? 183.755 127.118 125.712 1.00 55.35  ? 319 ALA C C   1 
ATOM   10446 O  O   . ALA C 2 319 ? 184.125 126.043 126.197 1.00 55.35  ? 319 ALA C O   1 
ATOM   10447 C  CB  . ALA C 2 319 ? 181.396 127.885 125.932 1.00 55.35  ? 319 ALA C CB  1 
ATOM   10448 N  N   . LEU C 2 320 ? 184.147 127.531 124.510 1.00 59.82  ? 320 LEU C N   1 
ATOM   10449 C  CA  . LEU C 2 320 ? 185.132 126.794 123.734 1.00 59.82  ? 320 LEU C CA  1 
ATOM   10450 C  C   . LEU C 2 320 ? 186.506 126.789 124.387 1.00 59.82  ? 320 LEU C C   1 
ATOM   10451 O  O   . LEU C 2 320 ? 186.742 125.970 125.282 1.00 59.82  ? 320 LEU C O   1 
ATOM   10452 C  CB  . LEU C 2 320 ? 185.237 127.389 122.328 1.00 59.82  ? 320 LEU C CB  1 
ATOM   10453 C  CG  . LEU C 2 320 ? 183.992 127.275 121.455 1.00 59.82  ? 320 LEU C CG  1 
ATOM   10454 C  CD1 . LEU C 2 320 ? 184.182 128.048 120.174 1.00 59.82  ? 320 LEU C CD1 1 
ATOM   10455 C  CD2 . LEU C 2 320 ? 183.691 125.822 121.154 1.00 59.82  ? 320 LEU C CD2 1 
ATOM   10456 N  N   . ASP C 2 321 ? 187.401 127.685 123.967 1.00 69.83  ? 321 ASP C N   1 
ATOM   10457 C  CA  . ASP C 2 321 ? 188.733 127.852 124.545 1.00 69.83  ? 321 ASP C CA  1 
ATOM   10458 C  C   . ASP C 2 321 ? 189.450 129.019 123.859 1.00 69.83  ? 321 ASP C C   1 
ATOM   10459 O  O   . ASP C 2 321 ? 190.393 129.621 124.374 1.00 69.83  ? 321 ASP C O   1 
ATOM   10460 C  CB  . ASP C 2 321 ? 189.551 126.559 124.427 1.00 69.83  ? 321 ASP C CB  1 
ATOM   10461 C  CG  . ASP C 2 321 ? 190.789 126.563 125.304 1.00 69.83  ? 321 ASP C CG  1 
ATOM   10462 O  OD1 . ASP C 2 321 ? 191.016 127.557 126.025 1.00 69.83  ? 321 ASP C OD1 1 
ATOM   10463 O  OD2 . ASP C 2 321 ? 191.540 125.566 125.269 1.00 69.83  ? 321 ASP C OD2 1 
ATOM   10464 N  N   . THR C 2 322 ? 188.939 129.328 122.669 1.00 69.98  ? 322 THR C N   1 
ATOM   10465 C  CA  . THR C 2 322 ? 189.561 130.269 121.748 1.00 69.98  ? 322 THR C CA  1 
ATOM   10466 C  C   . THR C 2 322 ? 189.518 131.676 122.321 1.00 69.98  ? 322 THR C C   1 
ATOM   10467 O  O   . THR C 2 322 ? 188.494 132.093 122.870 1.00 69.98  ? 322 THR C O   1 
ATOM   10468 C  CB  . THR C 2 322 ? 188.854 130.234 120.388 1.00 69.98  ? 322 THR C CB  1 
ATOM   10469 O  OG1 . THR C 2 322 ? 188.920 128.909 119.848 1.00 69.98  ? 322 THR C OG1 1 
ATOM   10470 C  CG2 . THR C 2 322 ? 189.502 131.203 119.414 1.00 69.98  ? 322 THR C CG2 1 
ATOM   10471 N  N   . GLU C 2 323 ? 190.630 132.396 122.193 1.00 74.19  ? 323 GLU C N   1 
ATOM   10472 C  CA  . GLU C 2 323 ? 190.662 133.817 122.499 1.00 74.19  ? 323 GLU C CA  1 
ATOM   10473 C  C   . GLU C 2 323 ? 190.284 134.622 121.263 1.00 74.19  ? 323 GLU C C   1 
ATOM   10474 O  O   . GLU C 2 323 ? 190.588 134.241 120.130 1.00 74.19  ? 323 GLU C O   1 
ATOM   10475 C  CB  . GLU C 2 323 ? 192.049 134.244 122.983 1.00 74.19  ? 323 GLU C CB  1 
ATOM   10476 C  CG  . GLU C 2 323 ? 192.474 133.634 124.306 1.00 74.19  ? 323 GLU C CG  1 
ATOM   10477 C  CD  . GLU C 2 323 ? 193.093 132.260 124.141 1.00 74.19  ? 323 GLU C CD  1 
ATOM   10478 O  OE1 . GLU C 2 323 ? 193.239 131.805 122.986 1.00 74.19  ? 323 GLU C OE1 1 
ATOM   10479 O  OE2 . GLU C 2 323 ? 193.441 131.637 125.165 1.00 74.19  ? 323 GLU C OE2 1 
ATOM   10480 N  N   . ILE C 2 324 ? 189.616 135.747 121.491 1.00 71.86  ? 324 ILE C N   1 
ATOM   10481 C  CA  . ILE C 2 324 ? 189.143 136.589 120.396 1.00 71.86  ? 324 ILE C CA  1 
ATOM   10482 C  C   . ILE C 2 324 ? 189.612 138.024 120.615 1.00 71.86  ? 324 ILE C C   1 
ATOM   10483 O  O   . ILE C 2 324 ? 189.648 138.499 121.760 1.00 71.86  ? 324 ILE C O   1 
ATOM   10484 C  CB  . ILE C 2 324 ? 187.616 136.502 120.258 1.00 71.86  ? 324 ILE C CB  1 
ATOM   10485 C  CG1 . ILE C 2 324 ? 186.938 136.905 121.565 1.00 71.86  ? 324 ILE C CG1 1 
ATOM   10486 C  CG2 . ILE C 2 324 ? 187.193 135.102 119.851 1.00 71.86  ? 324 ILE C CG2 1 
ATOM   10487 C  CD1 . ILE C 2 324 ? 185.450 137.008 121.456 1.00 71.86  ? 324 ILE C CD1 1 
ATOM   10488 N  N   . PRO C 2 325 ? 189.984 138.743 119.560 1.00 75.04  ? 325 PRO C N   1 
ATOM   10489 C  CA  . PRO C 2 325 ? 190.518 140.096 119.739 1.00 75.04  ? 325 PRO C CA  1 
ATOM   10490 C  C   . PRO C 2 325 ? 189.419 141.111 120.019 1.00 75.04  ? 325 PRO C C   1 
ATOM   10491 O  O   . PRO C 2 325 ? 188.226 140.801 120.026 1.00 75.04  ? 325 PRO C O   1 
ATOM   10492 C  CB  . PRO C 2 325 ? 191.204 140.381 118.401 1.00 75.04  ? 325 PRO C CB  1 
ATOM   10493 C  CG  . PRO C 2 325 ? 190.444 139.552 117.421 1.00 75.04  ? 325 PRO C CG  1 
ATOM   10494 C  CD  . PRO C 2 325 ? 190.031 138.307 118.154 1.00 75.04  ? 325 PRO C CD  1 
ATOM   10495 N  N   . ASN C 2 326 ? 189.850 142.353 120.252 1.00 75.78  ? 326 ASN C N   1 
ATOM   10496 C  CA  . ASN C 2 326 ? 188.904 143.426 120.539 1.00 75.78  ? 326 ASN C CA  1 
ATOM   10497 C  C   . ASN C 2 326 ? 188.211 143.912 119.274 1.00 75.78  ? 326 ASN C C   1 
ATOM   10498 O  O   . ASN C 2 326 ? 187.035 144.292 119.311 1.00 75.78  ? 326 ASN C O   1 
ATOM   10499 C  CB  . ASN C 2 326 ? 189.619 144.588 121.224 1.00 75.78  ? 326 ASN C CB  1 
ATOM   10500 C  CG  . ASN C 2 326 ? 190.171 144.214 122.577 1.00 75.78  ? 326 ASN C CG  1 
ATOM   10501 O  OD1 . ASN C 2 326 ? 191.384 144.183 122.780 1.00 75.78  ? 326 ASN C OD1 1 
ATOM   10502 N  ND2 . ASN C 2 326 ? 189.281 143.933 123.518 1.00 75.78  ? 326 ASN C ND2 1 
ATOM   10503 N  N   . GLU C 2 327 ? 188.921 143.913 118.150 1.00 79.32  ? 327 GLU C N   1 
ATOM   10504 C  CA  . GLU C 2 327 ? 188.388 144.485 116.921 1.00 79.32  ? 327 GLU C CA  1 
ATOM   10505 C  C   . GLU C 2 327 ? 187.250 143.629 116.381 1.00 79.32  ? 327 GLU C C   1 
ATOM   10506 O  O   . GLU C 2 327 ? 187.374 142.406 116.277 1.00 79.32  ? 327 GLU C O   1 
ATOM   10507 C  CB  . GLU C 2 327 ? 189.498 144.611 115.878 1.00 79.32  ? 327 GLU C CB  1 
ATOM   10508 C  CG  . GLU C 2 327 ? 190.601 145.588 116.260 1.00 79.32  ? 327 GLU C CG  1 
ATOM   10509 C  CD  . GLU C 2 327 ? 191.647 144.964 117.164 1.00 79.32  ? 327 GLU C CD  1 
ATOM   10510 O  OE1 . GLU C 2 327 ? 191.551 143.749 117.434 1.00 79.32  ? 327 GLU C OE1 1 
ATOM   10511 O  OE2 . GLU C 2 327 ? 192.563 145.689 117.606 1.00 79.32  ? 327 GLU C OE2 1 
ATOM   10512 N  N   . LEU C 2 328 ? 186.142 144.277 116.035 1.00 75.59  ? 328 LEU C N   1 
ATOM   10513 C  CA  . LEU C 2 328 ? 185.003 143.558 115.486 1.00 75.59  ? 328 LEU C CA  1 
ATOM   10514 C  C   . LEU C 2 328 ? 185.205 143.304 113.993 1.00 75.59  ? 328 LEU C C   1 
ATOM   10515 O  O   . LEU C 2 328 ? 185.361 144.250 113.214 1.00 75.59  ? 328 LEU C O   1 
ATOM   10516 C  CB  . LEU C 2 328 ? 183.711 144.344 115.700 1.00 75.59  ? 328 LEU C CB  1 
ATOM   10517 C  CG  . LEU C 2 328 ? 183.203 144.546 117.126 1.00 75.59  ? 328 LEU C CG  1 
ATOM   10518 C  CD1 . LEU C 2 328 ? 182.003 145.475 117.130 1.00 75.59  ? 328 LEU C CD1 1 
ATOM   10519 C  CD2 . LEU C 2 328 ? 182.839 143.220 117.748 1.00 75.59  ? 328 LEU C CD2 1 
ATOM   10520 N  N   . PRO C 2 329 ? 185.198 142.047 113.563 1.00 75.76  ? 329 PRO C N   1 
ATOM   10521 C  CA  . PRO C 2 329 ? 185.264 141.749 112.131 1.00 75.76  ? 329 PRO C CA  1 
ATOM   10522 C  C   . PRO C 2 329 ? 183.995 142.189 111.419 1.00 75.76  ? 329 PRO C C   1 
ATOM   10523 O  O   . PRO C 2 329 ? 182.988 142.540 112.036 1.00 75.76  ? 329 PRO C O   1 
ATOM   10524 C  CB  . PRO C 2 329 ? 185.413 140.225 112.094 1.00 75.76  ? 329 PRO C CB  1 
ATOM   10525 C  CG  . PRO C 2 329 ? 184.780 139.772 113.364 1.00 75.76  ? 329 PRO C CG  1 
ATOM   10526 C  CD  . PRO C 2 329 ? 185.086 140.829 114.377 1.00 75.76  ? 329 PRO C CD  1 
ATOM   10527 N  N   . TYR C 2 330 ? 184.059 142.155 110.092 1.00 80.67  ? 330 TYR C N   1 
ATOM   10528 C  CA  . TYR C 2 330 ? 182.960 142.684 109.297 1.00 80.67  ? 330 TYR C CA  1 
ATOM   10529 C  C   . TYR C 2 330 ? 181.741 141.776 109.391 1.00 80.67  ? 330 TYR C C   1 
ATOM   10530 O  O   . TYR C 2 330 ? 181.743 140.652 108.879 1.00 80.67  ? 330 TYR C O   1 
ATOM   10531 C  CB  . TYR C 2 330 ? 183.382 142.856 107.840 1.00 80.67  ? 330 TYR C CB  1 
ATOM   10532 C  CG  . TYR C 2 330 ? 182.318 143.532 107.007 1.00 80.67  ? 330 TYR C CG  1 
ATOM   10533 C  CD1 . TYR C 2 330 ? 182.108 144.903 107.103 1.00 80.67  ? 330 TYR C CD1 1 
ATOM   10534 C  CD2 . TYR C 2 330 ? 181.509 142.802 106.146 1.00 80.67  ? 330 TYR C CD2 1 
ATOM   10535 C  CE1 . TYR C 2 330 ? 181.129 145.529 106.358 1.00 80.67  ? 330 TYR C CE1 1 
ATOM   10536 C  CE2 . TYR C 2 330 ? 180.529 143.420 105.395 1.00 80.67  ? 330 TYR C CE2 1 
ATOM   10537 C  CZ  . TYR C 2 330 ? 180.344 144.783 105.505 1.00 80.67  ? 330 TYR C CZ  1 
ATOM   10538 O  OH  . TYR C 2 330 ? 179.370 145.403 104.760 1.00 80.67  ? 330 TYR C OH  1 
ATOM   10539 N  N   . ASN C 2 331 ? 180.699 142.271 110.053 1.00 73.83  ? 331 ASN C N   1 
ATOM   10540 C  CA  . ASN C 2 331 ? 179.440 141.553 110.180 1.00 73.83  ? 331 ASN C CA  1 
ATOM   10541 C  C   . ASN C 2 331 ? 178.399 142.268 109.325 1.00 73.83  ? 331 ASN C C   1 
ATOM   10542 O  O   . ASN C 2 331 ? 178.673 142.685 108.196 1.00 73.83  ? 331 ASN C O   1 
ATOM   10543 C  CB  . ASN C 2 331 ? 179.035 141.429 111.657 1.00 73.83  ? 331 ASN C CB  1 
ATOM   10544 C  CG  . ASN C 2 331 ? 178.904 142.773 112.351 1.00 73.83  ? 331 ASN C CG  1 
ATOM   10545 O  OD1 . ASN C 2 331 ? 179.011 143.826 111.726 1.00 73.83  ? 331 ASN C OD1 1 
ATOM   10546 N  ND2 . ASN C 2 331 ? 178.670 142.740 113.658 1.00 73.83  ? 331 ASN C ND2 1 
ATOM   10547 N  N   . ASP C 2 332 ? 177.192 142.408 109.864 1.00 73.69  ? 332 ASP C N   1 
ATOM   10548 C  CA  . ASP C 2 332 ? 176.122 143.130 109.191 1.00 73.69  ? 332 ASP C CA  1 
ATOM   10549 C  C   . ASP C 2 332 ? 175.504 144.218 110.055 1.00 73.69  ? 332 ASP C C   1 
ATOM   10550 O  O   . ASP C 2 332 ? 174.434 144.727 109.705 1.00 73.69  ? 332 ASP C O   1 
ATOM   10551 C  CB  . ASP C 2 332 ? 175.019 142.164 108.749 1.00 73.69  ? 332 ASP C CB  1 
ATOM   10552 C  CG  . ASP C 2 332 ? 175.471 141.221 107.662 1.00 73.69  ? 332 ASP C CG  1 
ATOM   10553 O  OD1 . ASP C 2 332 ? 176.372 141.599 106.886 1.00 73.69  ? 332 ASP C OD1 1 
ATOM   10554 O  OD2 . ASP C 2 332 ? 174.919 140.103 107.579 1.00 73.69  ? 332 ASP C OD2 1 
ATOM   10555 N  N   . TYR C 2 333 ? 176.135 144.589 111.165 1.00 71.10  ? 333 TYR C N   1 
ATOM   10556 C  CA  . TYR C 2 333 ? 175.489 145.453 112.143 1.00 71.10  ? 333 TYR C CA  1 
ATOM   10557 C  C   . TYR C 2 333 ? 176.474 146.436 112.765 1.00 71.10  ? 333 TYR C C   1 
ATOM   10558 O  O   . TYR C 2 333 ? 176.387 146.747 113.956 1.00 71.10  ? 333 TYR C O   1 
ATOM   10559 C  CB  . TYR C 2 333 ? 174.811 144.622 113.230 1.00 71.10  ? 333 TYR C CB  1 
ATOM   10560 C  CG  . TYR C 2 333 ? 173.709 143.714 112.724 1.00 71.10  ? 333 TYR C CG  1 
ATOM   10561 C  CD1 . TYR C 2 333 ? 172.447 144.210 112.440 1.00 71.10  ? 333 TYR C CD1 1 
ATOM   10562 C  CD2 . TYR C 2 333 ? 173.932 142.358 112.543 1.00 71.10  ? 333 TYR C CD2 1 
ATOM   10563 C  CE1 . TYR C 2 333 ? 171.441 143.383 111.981 1.00 71.10  ? 333 TYR C CE1 1 
ATOM   10564 C  CE2 . TYR C 2 333 ? 172.932 141.525 112.085 1.00 71.10  ? 333 TYR C CE2 1 
ATOM   10565 C  CZ  . TYR C 2 333 ? 171.689 142.043 111.806 1.00 71.10  ? 333 TYR C CZ  1 
ATOM   10566 O  OH  . TYR C 2 333 ? 170.689 141.216 111.349 1.00 71.10  ? 333 TYR C OH  1 
ATOM   10567 N  N   . PHE C 2 334 ? 177.424 146.953 111.977 1.00 76.71  ? 334 PHE C N   1 
ATOM   10568 C  CA  . PHE C 2 334 ? 178.290 148.015 112.489 1.00 76.71  ? 334 PHE C CA  1 
ATOM   10569 C  C   . PHE C 2 334 ? 177.499 149.274 112.814 1.00 76.71  ? 334 PHE C C   1 
ATOM   10570 O  O   . PHE C 2 334 ? 177.903 150.057 113.681 1.00 76.71  ? 334 PHE C O   1 
ATOM   10571 C  CB  . PHE C 2 334 ? 179.405 148.348 111.499 1.00 76.71  ? 334 PHE C CB  1 
ATOM   10572 C  CG  . PHE C 2 334 ? 180.575 147.421 111.563 1.00 76.71  ? 334 PHE C CG  1 
ATOM   10573 C  CD1 . PHE C 2 334 ? 181.518 147.555 112.564 1.00 76.71  ? 334 PHE C CD1 1 
ATOM   10574 C  CD2 . PHE C 2 334 ? 180.757 146.448 110.610 1.00 76.71  ? 334 PHE C CD2 1 
ATOM   10575 C  CE1 . PHE C 2 334 ? 182.605 146.718 112.622 1.00 76.71  ? 334 PHE C CE1 1 
ATOM   10576 C  CE2 . PHE C 2 334 ? 181.844 145.610 110.665 1.00 76.71  ? 334 PHE C CE2 1 
ATOM   10577 C  CZ  . PHE C 2 334 ? 182.769 145.747 111.670 1.00 76.71  ? 334 PHE C CZ  1 
ATOM   10578 N  N   . GLU C 2 335 ? 176.366 149.482 112.140 1.00 79.47  ? 335 GLU C N   1 
ATOM   10579 C  CA  . GLU C 2 335 ? 175.534 150.645 112.427 1.00 79.47  ? 335 GLU C CA  1 
ATOM   10580 C  C   . GLU C 2 335 ? 174.883 150.566 113.802 1.00 79.47  ? 335 GLU C C   1 
ATOM   10581 O  O   . GLU C 2 335 ? 174.214 151.519 114.215 1.00 79.47  ? 335 GLU C O   1 
ATOM   10582 C  CB  . GLU C 2 335 ? 174.459 150.802 111.349 1.00 79.47  ? 335 GLU C CB  1 
ATOM   10583 C  CG  . GLU C 2 335 ? 175.010 151.149 109.976 1.00 79.47  ? 335 GLU C CG  1 
ATOM   10584 C  CD  . GLU C 2 335 ? 175.463 149.927 109.201 1.00 79.47  ? 335 GLU C CD  1 
ATOM   10585 O  OE1 . GLU C 2 335 ? 175.253 148.797 109.689 1.00 79.47  ? 335 GLU C OE1 1 
ATOM   10586 O  OE2 . GLU C 2 335 ? 176.039 150.099 108.107 1.00 79.47  ? 335 GLU C OE2 1 
ATOM   10587 N  N   . TYR C 2 336 ? 175.060 149.454 114.516 1.00 74.92  ? 336 TYR C N   1 
ATOM   10588 C  CA  . TYR C 2 336 ? 174.516 149.306 115.860 1.00 74.92  ? 336 TYR C CA  1 
ATOM   10589 C  C   . TYR C 2 336 ? 175.591 149.413 116.932 1.00 74.92  ? 336 TYR C C   1 
ATOM   10590 O  O   . TYR C 2 336 ? 175.324 149.924 118.024 1.00 74.92  ? 336 TYR C O   1 
ATOM   10591 C  CB  . TYR C 2 336 ? 173.786 147.967 115.994 1.00 74.92  ? 336 TYR C CB  1 
ATOM   10592 C  CG  . TYR C 2 336 ? 172.507 147.877 115.192 1.00 74.92  ? 336 TYR C CG  1 
ATOM   10593 C  CD1 . TYR C 2 336 ? 171.919 149.013 114.657 1.00 74.92  ? 336 TYR C CD1 1 
ATOM   10594 C  CD2 . TYR C 2 336 ? 171.885 146.658 114.976 1.00 74.92  ? 336 TYR C CD2 1 
ATOM   10595 C  CE1 . TYR C 2 336 ? 170.752 148.935 113.925 1.00 74.92  ? 336 TYR C CE1 1 
ATOM   10596 C  CE2 . TYR C 2 336 ? 170.715 146.572 114.244 1.00 74.92  ? 336 TYR C CE2 1 
ATOM   10597 C  CZ  . TYR C 2 336 ? 170.155 147.714 113.722 1.00 74.92  ? 336 TYR C CZ  1 
ATOM   10598 O  OH  . TYR C 2 336 ? 168.991 147.635 112.993 1.00 74.92  ? 336 TYR C OH  1 
ATOM   10599 N  N   . PHE C 2 337 ? 176.804 148.933 116.648 1.00 70.26  ? 337 PHE C N   1 
ATOM   10600 C  CA  . PHE C 2 337 ? 177.918 149.029 117.583 1.00 70.26  ? 337 PHE C CA  1 
ATOM   10601 C  C   . PHE C 2 337 ? 178.540 150.420 117.604 1.00 70.26  ? 337 PHE C C   1 
ATOM   10602 O  O   . PHE C 2 337 ? 178.666 151.053 116.547 1.00 70.26  ? 337 PHE C O   1 
ATOM   10603 C  CB  . PHE C 2 337 ? 178.967 147.965 117.257 1.00 70.26  ? 337 PHE C CB  1 
ATOM   10604 C  CG  . PHE C 2 337 ? 178.480 146.559 117.469 1.00 70.26  ? 337 PHE C CG  1 
ATOM   10605 C  CD1 . PHE C 2 337 ? 178.459 146.002 118.733 1.00 70.26  ? 337 PHE C CD1 1 
ATOM   10606 C  CD2 . PHE C 2 337 ? 178.026 145.802 116.406 1.00 70.26  ? 337 PHE C CD2 1 
ATOM   10607 C  CE1 . PHE C 2 337 ? 178.002 144.713 118.929 1.00 70.26  ? 337 PHE C CE1 1 
ATOM   10608 C  CE2 . PHE C 2 337 ? 177.568 144.514 116.598 1.00 70.26  ? 337 PHE C CE2 1 
ATOM   10609 C  CZ  . PHE C 2 337 ? 177.557 143.970 117.859 1.00 70.26  ? 337 PHE C CZ  1 
ATOM   10610 N  N   . GLY C 2 338 ? 178.924 150.915 118.779 1.00 80.14  ? 338 GLY C N   1 
ATOM   10611 C  CA  . GLY C 2 338 ? 179.350 152.286 118.941 1.00 80.14  ? 338 GLY C CA  1 
ATOM   10612 C  C   . GLY C 2 338 ? 180.589 152.650 118.149 1.00 80.14  ? 338 GLY C C   1 
ATOM   10613 O  O   . GLY C 2 338 ? 181.282 151.790 117.597 1.00 80.14  ? 338 GLY C O   1 
ATOM   10614 N  N   . PRO C 2 339 ? 180.896 153.956 118.082 1.00 83.25  ? 339 PRO C N   1 
ATOM   10615 C  CA  . PRO C 2 339 ? 182.040 154.505 117.345 1.00 83.25  ? 339 PRO C CA  1 
ATOM   10616 C  C   . PRO C 2 339 ? 183.388 154.143 117.962 1.00 83.25  ? 339 PRO C C   1 
ATOM   10617 O  O   . PRO C 2 339 ? 184.156 155.025 118.345 1.00 83.25  ? 339 PRO C O   1 
ATOM   10618 C  CB  . PRO C 2 339 ? 181.806 156.015 117.411 1.00 83.25  ? 339 PRO C CB  1 
ATOM   10619 C  CG  . PRO C 2 339 ? 181.006 156.214 118.647 1.00 83.25  ? 339 PRO C CG  1 
ATOM   10620 C  CD  . PRO C 2 339 ? 180.117 155.012 118.753 1.00 83.25  ? 339 PRO C CD  1 
ATOM   10621 N  N   . ASP C 2 340 ? 183.661 152.844 118.053 1.00 80.09  ? 340 ASP C N   1 
ATOM   10622 C  CA  . ASP C 2 340 ? 184.939 152.344 118.542 1.00 80.09  ? 340 ASP C CA  1 
ATOM   10623 C  C   . ASP C 2 340 ? 185.187 150.953 117.976 1.00 80.09  ? 340 ASP C C   1 
ATOM   10624 O  O   . ASP C 2 340 ? 186.338 150.548 117.781 1.00 80.09  ? 340 ASP C O   1 
ATOM   10625 C  CB  . ASP C 2 340 ? 184.971 152.331 120.072 1.00 80.09  ? 340 ASP C CB  1 
ATOM   10626 C  CG  . ASP C 2 340 ? 183.867 151.481 120.677 1.00 80.09  ? 340 ASP C CG  1 
ATOM   10627 O  OD1 . ASP C 2 340 ? 183.019 150.965 119.920 1.00 80.09  ? 340 ASP C OD1 1 
ATOM   10628 O  OD2 . ASP C 2 340 ? 183.849 151.328 121.916 1.00 80.09  ? 340 ASP C OD2 1 
ATOM   10629 N  N   . PHE C 2 341 ? 184.104 150.225 117.715 1.00 77.38  ? 341 PHE C N   1 
ATOM   10630 C  CA  . PHE C 2 341 ? 184.144 148.917 117.068 1.00 77.38  ? 341 PHE C CA  1 
ATOM   10631 C  C   . PHE C 2 341 ? 185.017 147.945 117.860 1.00 77.38  ? 341 PHE C C   1 
ATOM   10632 O  O   . PHE C 2 341 ? 185.849 147.217 117.317 1.00 77.38  ? 341 PHE C O   1 
ATOM   10633 C  CB  . PHE C 2 341 ? 184.623 149.047 115.620 1.00 77.38  ? 341 PHE C CB  1 
ATOM   10634 C  CG  . PHE C 2 341 ? 183.680 149.817 114.739 1.00 77.38  ? 341 PHE C CG  1 
ATOM   10635 C  CD1 . PHE C 2 341 ? 182.372 150.047 115.132 1.00 77.38  ? 341 PHE C CD1 1 
ATOM   10636 C  CD2 . PHE C 2 341 ? 184.105 150.324 113.524 1.00 77.38  ? 341 PHE C CD2 1 
ATOM   10637 C  CE1 . PHE C 2 341 ? 181.505 150.759 114.328 1.00 77.38  ? 341 PHE C CE1 1 
ATOM   10638 C  CE2 . PHE C 2 341 ? 183.242 151.038 112.716 1.00 77.38  ? 341 PHE C CE2 1 
ATOM   10639 C  CZ  . PHE C 2 341 ? 181.941 151.255 113.119 1.00 77.38  ? 341 PHE C CZ  1 
ATOM   10640 N  N   . LYS C 2 342 ? 184.811 147.954 119.174 1.00 74.19  ? 342 LYS C N   1 
ATOM   10641 C  CA  . LYS C 2 342 ? 185.539 147.088 120.087 1.00 74.19  ? 342 LYS C CA  1 
ATOM   10642 C  C   . LYS C 2 342 ? 184.555 146.203 120.836 1.00 74.19  ? 342 LYS C C   1 
ATOM   10643 O  O   . LYS C 2 342 ? 183.385 146.548 121.014 1.00 74.19  ? 342 LYS C O   1 
ATOM   10644 C  CB  . LYS C 2 342 ? 186.383 147.896 121.080 1.00 74.19  ? 342 LYS C CB  1 
ATOM   10645 C  CG  . LYS C 2 342 ? 187.431 148.777 120.425 1.00 74.19  ? 342 LYS C CG  1 
ATOM   10646 C  CD  . LYS C 2 342 ? 188.489 147.947 119.721 1.00 74.19  ? 342 LYS C CD  1 
ATOM   10647 C  CE  . LYS C 2 342 ? 189.613 148.821 119.192 1.00 74.19  ? 342 LYS C CE  1 
ATOM   10648 N  NZ  . LYS C 2 342 ? 189.155 149.678 118.063 1.00 74.19  ? 342 LYS C NZ  1 
ATOM   10649 N  N   . LEU C 2 343 ? 185.048 145.047 121.273 1.00 65.48  ? 343 LEU C N   1 
ATOM   10650 C  CA  . LEU C 2 343 ? 184.222 144.081 121.984 1.00 65.48  ? 343 LEU C CA  1 
ATOM   10651 C  C   . LEU C 2 343 ? 184.005 144.457 123.444 1.00 65.48  ? 343 LEU C C   1 
ATOM   10652 O  O   . LEU C 2 343 ? 182.860 144.623 123.875 1.00 65.48  ? 343 LEU C O   1 
ATOM   10653 C  CB  . LEU C 2 343 ? 184.853 142.690 121.904 1.00 65.48  ? 343 LEU C CB  1 
ATOM   10654 C  CG  . LEU C 2 343 ? 184.078 141.568 122.594 1.00 65.48  ? 343 LEU C CG  1 
ATOM   10655 C  CD1 . LEU C 2 343 ? 182.742 141.335 121.917 1.00 65.48  ? 343 LEU C CD1 1 
ATOM   10656 C  CD2 . LEU C 2 343 ? 184.898 140.300 122.622 1.00 65.48  ? 343 LEU C CD2 1 
ATOM   10657 N  N   . HIS C 2 344 ? 185.077 144.593 124.214 1.00 65.53  ? 344 HIS C N   1 
ATOM   10658 C  CA  . HIS C 2 344 ? 184.969 144.830 125.645 1.00 65.53  ? 344 HIS C CA  1 
ATOM   10659 C  C   . HIS C 2 344 ? 184.496 146.247 125.934 1.00 65.53  ? 344 HIS C C   1 
ATOM   10660 O  O   . HIS C 2 344 ? 184.955 147.217 125.326 1.00 65.53  ? 344 HIS C O   1 
ATOM   10661 C  CB  . HIS C 2 344 ? 186.308 144.579 126.336 1.00 65.53  ? 344 HIS C CB  1 
ATOM   10662 C  CG  . HIS C 2 344 ? 186.724 143.143 126.335 1.00 65.53  ? 344 HIS C CG  1 
ATOM   10663 N  ND1 . HIS C 2 344 ? 187.445 142.578 125.306 1.00 65.53  ? 344 HIS C ND1 1 
ATOM   10664 C  CD2 . HIS C 2 344 ? 186.522 142.156 127.238 1.00 65.53  ? 344 HIS C CD2 1 
ATOM   10665 C  CE1 . HIS C 2 344 ? 187.670 141.305 125.575 1.00 65.53  ? 344 HIS C CE1 1 
ATOM   10666 N  NE2 . HIS C 2 344 ? 187.120 141.023 126.742 1.00 65.53  ? 344 HIS C NE2 1 
ATOM   10667 N  N   . ILE C 2 345 ? 183.568 146.354 126.878 1.00 63.27  ? 345 ILE C N   1 
ATOM   10668 C  CA  . ILE C 2 345 ? 183.034 147.632 127.320 1.00 63.27  ? 345 ILE C CA  1 
ATOM   10669 C  C   . ILE C 2 345 ? 183.751 148.041 128.596 1.00 63.27  ? 345 ILE C C   1 
ATOM   10670 O  O   . ILE C 2 345 ? 184.512 147.264 129.181 1.00 63.27  ? 345 ILE C O   1 
ATOM   10671 C  CB  . ILE C 2 345 ? 181.510 147.570 127.549 1.00 63.27  ? 345 ILE C CB  1 
ATOM   10672 C  CG1 . ILE C 2 345 ? 181.181 146.582 128.668 1.00 63.27  ? 345 ILE C CG1 1 
ATOM   10673 C  CG2 . ILE C 2 345 ? 180.804 147.173 126.269 1.00 63.27  ? 345 ILE C CG2 1 
ATOM   10674 C  CD1 . ILE C 2 345 ? 179.739 146.622 129.113 1.00 63.27  ? 345 ILE C CD1 1 
ATOM   10675 N  N   . SER C 2 346 ? 183.502 149.259 129.024 1.00 66.14  ? 346 SER C N   1 
ATOM   10676 C  CA  . SER C 2 346 ? 184.137 149.773 130.226 1.00 66.14  ? 346 SER C CA  1 
ATOM   10677 C  C   . SER C 2 346 ? 183.088 150.142 131.269 1.00 66.14  ? 346 SER C C   1 
ATOM   10678 O  O   . SER C 2 346 ? 181.967 150.527 130.922 1.00 66.14  ? 346 SER C O   1 
ATOM   10679 C  CB  . SER C 2 346 ? 184.983 150.999 129.895 1.00 66.14  ? 346 SER C CB  1 
ATOM   10680 O  OG  . SER C 2 346 ? 184.171 152.076 129.460 1.00 66.14  ? 346 SER C OG  1 
ATOM   10681 N  N   . PRO C 2 347 ? 183.418 150.027 132.553 1.00 62.64  ? 347 PRO C N   1 
ATOM   10682 C  CA  . PRO C 2 347 ? 182.455 150.392 133.595 1.00 62.64  ? 347 PRO C CA  1 
ATOM   10683 C  C   . PRO C 2 347 ? 182.171 151.885 133.593 1.00 62.64  ? 347 PRO C C   1 
ATOM   10684 O  O   . PRO C 2 347 ? 182.828 152.677 132.914 1.00 62.64  ? 347 PRO C O   1 
ATOM   10685 C  CB  . PRO C 2 347 ? 183.149 149.958 134.890 1.00 62.64  ? 347 PRO C CB  1 
ATOM   10686 C  CG  . PRO C 2 347 ? 184.598 149.974 134.560 1.00 62.64  ? 347 PRO C CG  1 
ATOM   10687 C  CD  . PRO C 2 347 ? 184.696 149.565 133.120 1.00 62.64  ? 347 PRO C CD  1 
ATOM   10688 N  N   . SER C 2 348 ? 181.164 152.264 134.372 1.00 63.86  ? 348 SER C N   1 
ATOM   10689 C  CA  . SER C 2 348 ? 180.718 153.649 134.421 1.00 63.86  ? 348 SER C CA  1 
ATOM   10690 C  C   . SER C 2 348 ? 181.279 154.331 135.668 1.00 63.86  ? 348 SER C C   1 
ATOM   10691 O  O   . SER C 2 348 ? 182.416 154.093 136.083 1.00 63.86  ? 348 SER C O   1 
ATOM   10692 C  CB  . SER C 2 348 ? 179.195 153.711 134.370 1.00 63.86  ? 348 SER C CB  1 
ATOM   10693 O  OG  . SER C 2 348 ? 178.622 153.130 135.527 1.00 63.86  ? 348 SER C OG  1 
ATOM   10694 N  N   . ASN C 2 349 ? 180.475 155.196 136.280 1.00 67.28  ? 349 ASN C N   1 
ATOM   10695 C  CA  . ASN C 2 349 ? 180.881 155.962 137.449 1.00 67.28  ? 349 ASN C CA  1 
ATOM   10696 C  C   . ASN C 2 349 ? 180.108 155.574 138.702 1.00 67.28  ? 349 ASN C C   1 
ATOM   10697 O  O   . ASN C 2 349 ? 180.343 156.155 139.766 1.00 67.28  ? 349 ASN C O   1 
ATOM   10698 C  CB  . ASN C 2 349 ? 180.703 157.458 137.178 1.00 67.28  ? 349 ASN C CB  1 
ATOM   10699 C  CG  . ASN C 2 349 ? 181.652 157.975 136.119 1.00 67.28  ? 349 ASN C CG  1 
ATOM   10700 O  OD1 . ASN C 2 349 ? 182.833 157.630 136.106 1.00 67.28  ? 349 ASN C OD1 1 
ATOM   10701 N  ND2 . ASN C 2 349 ? 181.137 158.799 135.216 1.00 67.28  ? 349 ASN C ND2 1 
ATOM   10702 N  N   . MET C 2 350 ? 179.201 154.607 138.600 1.00 64.72  ? 350 MET C N   1 
ATOM   10703 C  CA  . MET C 2 350 ? 178.332 154.267 139.717 1.00 64.72  ? 350 MET C CA  1 
ATOM   10704 C  C   . MET C 2 350 ? 179.122 153.603 140.840 1.00 64.72  ? 350 MET C C   1 
ATOM   10705 O  O   . MET C 2 350 ? 179.961 152.730 140.601 1.00 64.72  ? 350 MET C O   1 
ATOM   10706 C  CB  . MET C 2 350 ? 177.209 153.349 139.234 1.00 64.72  ? 350 MET C CB  1 
ATOM   10707 C  CG  . MET C 2 350 ? 176.158 153.034 140.277 1.00 64.72  ? 350 MET C CG  1 
ATOM   10708 S  SD  . MET C 2 350 ? 174.836 152.011 139.611 1.00 64.72  ? 350 MET C SD  1 
ATOM   10709 C  CE  . MET C 2 350 ? 173.970 153.199 138.590 1.00 64.72  ? 350 MET C CE  1 
ATOM   10710 N  N   . THR C 2 351 ? 178.849 154.027 142.071 1.00 63.52  ? 351 THR C N   1 
ATOM   10711 C  CA  . THR C 2 351 ? 179.503 153.497 143.261 1.00 63.52  ? 351 THR C CA  1 
ATOM   10712 C  C   . THR C 2 351 ? 178.628 152.415 143.879 1.00 63.52  ? 351 THR C C   1 
ATOM   10713 O  O   . THR C 2 351 ? 177.397 152.502 143.827 1.00 63.52  ? 351 THR C O   1 
ATOM   10714 C  CB  . THR C 2 351 ? 179.783 154.610 144.278 1.00 63.52  ? 351 THR C CB  1 
ATOM   10715 O  OG1 . THR C 2 351 ? 180.538 154.083 145.376 1.00 63.52  ? 351 THR C OG1 1 
ATOM   10716 C  CG2 . THR C 2 351 ? 178.488 155.215 144.802 1.00 63.52  ? 351 THR C CG2 1 
ATOM   10717 N  N   . ASN C 2 352 ? 179.263 151.396 144.454 1.00 60.68  ? 352 ASN C N   1 
ATOM   10718 C  CA  . ASN C 2 352 ? 178.516 150.286 145.031 1.00 60.68  ? 352 ASN C CA  1 
ATOM   10719 C  C   . ASN C 2 352 ? 178.176 150.554 146.492 1.00 60.68  ? 352 ASN C C   1 
ATOM   10720 O  O   . ASN C 2 352 ? 179.042 150.913 147.293 1.00 60.68  ? 352 ASN C O   1 
ATOM   10721 C  CB  . ASN C 2 352 ? 179.295 148.976 144.878 1.00 60.68  ? 352 ASN C CB  1 
ATOM   10722 C  CG  . ASN C 2 352 ? 180.712 149.056 145.412 1.00 60.68  ? 352 ASN C CG  1 
ATOM   10723 O  OD1 . ASN C 2 352 ? 181.139 150.076 145.948 1.00 60.68  ? 352 ASN C OD1 1 
ATOM   10724 N  ND2 . ASN C 2 352 ? 181.454 147.964 145.264 1.00 60.68  ? 352 ASN C ND2 1 
ATOM   10725 N  N   . GLN C 2 353 ? 176.902 150.387 146.834 1.00 63.19  ? 353 GLN C N   1 
ATOM   10726 C  CA  . GLN C 2 353 ? 176.418 150.657 148.179 1.00 63.19  ? 353 GLN C CA  1 
ATOM   10727 C  C   . GLN C 2 353 ? 176.479 149.438 149.089 1.00 63.19  ? 353 GLN C C   1 
ATOM   10728 O  O   . GLN C 2 353 ? 175.990 149.505 150.221 1.00 63.19  ? 353 GLN C O   1 
ATOM   10729 C  CB  . GLN C 2 353 ? 174.984 151.192 148.125 1.00 63.19  ? 353 GLN C CB  1 
ATOM   10730 C  CG  . GLN C 2 353 ? 174.838 152.532 147.413 1.00 63.19  ? 353 GLN C CG  1 
ATOM   10731 C  CD  . GLN C 2 353 ? 175.525 153.667 148.144 1.00 63.19  ? 353 GLN C CD  1 
ATOM   10732 O  OE1 . GLN C 2 353 ? 175.511 153.728 149.373 1.00 63.19  ? 353 GLN C OE1 1 
ATOM   10733 N  NE2 . GLN C 2 353 ? 176.127 154.578 147.389 1.00 63.19  ? 353 GLN C NE2 1 
ATOM   10734 N  N   . ASN C 2 354 ? 177.059 148.333 148.627 1.00 62.77  ? 354 ASN C N   1 
ATOM   10735 C  CA  . ASN C 2 354 ? 177.270 147.143 149.450 1.00 62.77  ? 354 ASN C CA  1 
ATOM   10736 C  C   . ASN C 2 354 ? 178.694 147.192 150.003 1.00 62.77  ? 354 ASN C C   1 
ATOM   10737 O  O   . ASN C 2 354 ? 179.657 146.830 149.324 1.00 62.77  ? 354 ASN C O   1 
ATOM   10738 C  CB  . ASN C 2 354 ? 176.973 145.879 148.647 1.00 62.77  ? 354 ASN C CB  1 
ATOM   10739 C  CG  . ASN C 2 354 ? 177.647 145.864 147.288 1.00 62.77  ? 354 ASN C CG  1 
ATOM   10740 O  OD1 . ASN C 2 354 ? 178.442 146.741 146.960 1.00 62.77  ? 354 ASN C OD1 1 
ATOM   10741 N  ND2 . ASN C 2 354 ? 177.308 144.869 146.477 1.00 62.77  ? 354 ASN C ND2 1 
ATOM   10742 N  N   . THR C 2 355 ? 178.817 147.638 151.251 1.00 67.12  ? 355 THR C N   1 
ATOM   10743 C  CA  . THR C 2 355 ? 180.107 148.035 151.790 1.00 67.12  ? 355 THR C CA  1 
ATOM   10744 C  C   . THR C 2 355 ? 180.812 146.850 152.451 1.00 67.12  ? 355 THR C C   1 
ATOM   10745 O  O   . THR C 2 355 ? 180.863 146.723 153.678 1.00 67.12  ? 355 THR C O   1 
ATOM   10746 C  CB  . THR C 2 355 ? 179.932 149.179 152.791 1.00 67.12  ? 355 THR C CB  1 
ATOM   10747 O  OG1 . THR C 2 355 ? 179.203 150.246 152.171 1.00 67.12  ? 355 THR C OG1 1 
ATOM   10748 C  CG2 . THR C 2 355 ? 181.287 149.721 153.236 1.00 67.12  ? 355 THR C CG2 1 
ATOM   10749 N  N   . ASN C 2 356 ? 181.347 145.964 151.605 1.00 68.10  ? 356 ASN C N   1 
ATOM   10750 C  CA  . ASN C 2 356 ? 182.275 144.930 152.064 1.00 68.10  ? 356 ASN C CA  1 
ATOM   10751 C  C   . ASN C 2 356 ? 181.690 144.100 153.204 1.00 68.10  ? 356 ASN C C   1 
ATOM   10752 O  O   . ASN C 2 356 ? 181.320 142.937 153.006 1.00 68.10  ? 356 ASN C O   1 
ATOM   10753 C  CB  . ASN C 2 356 ? 183.599 145.573 152.481 1.00 68.10  ? 356 ASN C CB  1 
ATOM   10754 C  CG  . ASN C 2 356 ? 184.710 144.559 152.665 1.00 68.10  ? 356 ASN C CG  1 
ATOM   10755 O  OD1 . ASN C 2 356 ? 184.503 143.355 152.514 1.00 68.10  ? 356 ASN C OD1 1 
ATOM   10756 N  ND2 . ASN C 2 356 ? 185.902 145.045 152.984 1.00 68.10  ? 356 ASN C ND2 1 
ATOM   10757 N  N   . GLU C 2 357 ? 181.605 144.676 154.408 1.00 67.65  ? 357 GLU C N   1 
ATOM   10758 C  CA  . GLU C 2 357 ? 181.120 143.921 155.560 1.00 67.65  ? 357 GLU C CA  1 
ATOM   10759 C  C   . GLU C 2 357 ? 179.675 143.475 155.370 1.00 67.65  ? 357 GLU C C   1 
ATOM   10760 O  O   . GLU C 2 357 ? 179.234 142.501 155.990 1.00 67.65  ? 357 GLU C O   1 
ATOM   10761 C  CB  . GLU C 2 357 ? 181.272 144.751 156.835 1.00 67.65  ? 357 GLU C CB  1 
ATOM   10762 C  CG  . GLU C 2 357 ? 180.508 146.065 156.836 1.00 67.65  ? 357 GLU C CG  1 
ATOM   10763 C  CD  . GLU C 2 357 ? 179.086 145.914 157.333 1.00 67.65  ? 357 GLU C CD  1 
ATOM   10764 O  OE1 . GLU C 2 357 ? 178.793 144.902 158.003 1.00 67.65  ? 357 GLU C OE1 1 
ATOM   10765 O  OE2 . GLU C 2 357 ? 178.261 146.810 157.055 1.00 67.65  ? 357 GLU C OE2 1 
ATOM   10766 N  N   . TYR C 2 358 ? 178.918 144.183 154.530 1.00 62.72  ? 358 TYR C N   1 
ATOM   10767 C  CA  . TYR C 2 358 ? 177.619 143.679 154.100 1.00 62.72  ? 358 TYR C CA  1 
ATOM   10768 C  C   . TYR C 2 358 ? 177.771 142.333 153.404 1.00 62.72  ? 358 TYR C C   1 
ATOM   10769 O  O   . TYR C 2 358 ? 177.133 141.342 153.785 1.00 62.72  ? 358 TYR C O   1 
ATOM   10770 C  CB  . TYR C 2 358 ? 176.957 144.701 153.176 1.00 62.72  ? 358 TYR C CB  1 
ATOM   10771 C  CG  . TYR C 2 358 ? 175.625 144.276 152.608 1.00 62.72  ? 358 TYR C CG  1 
ATOM   10772 C  CD1 . TYR C 2 358 ? 174.482 144.277 153.390 1.00 62.72  ? 358 TYR C CD1 1 
ATOM   10773 C  CD2 . TYR C 2 358 ? 175.510 143.889 151.282 1.00 62.72  ? 358 TYR C CD2 1 
ATOM   10774 C  CE1 . TYR C 2 358 ? 173.262 143.893 152.868 1.00 62.72  ? 358 TYR C CE1 1 
ATOM   10775 C  CE2 . TYR C 2 358 ? 174.297 143.505 150.752 1.00 62.72  ? 358 TYR C CE2 1 
ATOM   10776 C  CZ  . TYR C 2 358 ? 173.176 143.510 151.550 1.00 62.72  ? 358 TYR C CZ  1 
ATOM   10777 O  OH  . TYR C 2 358 ? 171.962 143.129 151.032 1.00 62.72  ? 358 TYR C OH  1 
ATOM   10778 N  N   . LEU C 2 359 ? 178.640 142.279 152.392 1.00 60.87  ? 359 LEU C N   1 
ATOM   10779 C  CA  . LEU C 2 359 ? 178.886 141.035 151.673 1.00 60.87  ? 359 LEU C CA  1 
ATOM   10780 C  C   . LEU C 2 359 ? 179.420 139.955 152.605 1.00 60.87  ? 359 LEU C C   1 
ATOM   10781 O  O   . LEU C 2 359 ? 179.162 138.764 152.400 1.00 60.87  ? 359 LEU C O   1 
ATOM   10782 C  CB  . LEU C 2 359 ? 179.868 141.290 150.531 1.00 60.87  ? 359 LEU C CB  1 
ATOM   10783 C  CG  . LEU C 2 359 ? 179.402 142.276 149.459 1.00 60.87  ? 359 LEU C CG  1 
ATOM   10784 C  CD1 . LEU C 2 359 ? 180.524 142.581 148.483 1.00 60.87  ? 359 LEU C CD1 1 
ATOM   10785 C  CD2 . LEU C 2 359 ? 178.183 141.744 148.731 1.00 60.87  ? 359 LEU C CD2 1 
ATOM   10786 N  N   . GLU C 2 360 ? 180.165 140.354 153.639 1.00 65.41  ? 360 GLU C N   1 
ATOM   10787 C  CA  . GLU C 2 360 ? 180.725 139.377 154.565 1.00 65.41  ? 360 GLU C CA  1 
ATOM   10788 C  C   . GLU C 2 360 ? 179.652 138.786 155.468 1.00 65.41  ? 360 GLU C C   1 
ATOM   10789 O  O   . GLU C 2 360 ? 179.610 137.569 155.677 1.00 65.41  ? 360 GLU C O   1 
ATOM   10790 C  CB  . GLU C 2 360 ? 181.833 140.015 155.399 1.00 65.41  ? 360 GLU C CB  1 
ATOM   10791 C  CG  . GLU C 2 360 ? 182.467 139.063 156.396 1.00 65.41  ? 360 GLU C CG  1 
ATOM   10792 C  CD  . GLU C 2 360 ? 183.204 137.921 155.727 1.00 65.41  ? 360 GLU C CD  1 
ATOM   10793 O  OE1 . GLU C 2 360 ? 183.673 138.101 154.584 1.00 65.41  ? 360 GLU C OE1 1 
ATOM   10794 O  OE2 . GLU C 2 360 ? 183.310 136.840 156.344 1.00 65.41  ? 360 GLU C OE2 1 
ATOM   10795 N  N   . LYS C 2 361 ? 178.778 139.630 156.020 1.00 63.62  ? 361 LYS C N   1 
ATOM   10796 C  CA  . LYS C 2 361 ? 177.708 139.120 156.871 1.00 63.62  ? 361 LYS C CA  1 
ATOM   10797 C  C   . LYS C 2 361 ? 176.741 138.252 156.075 1.00 63.62  ? 361 LYS C C   1 
ATOM   10798 O  O   . LYS C 2 361 ? 176.346 137.168 156.530 1.00 63.62  ? 361 LYS C O   1 
ATOM   10799 C  CB  . LYS C 2 361 ? 176.973 140.279 157.541 1.00 63.62  ? 361 LYS C CB  1 
ATOM   10800 C  CG  . LYS C 2 361 ? 177.812 141.028 158.563 1.00 63.62  ? 361 LYS C CG  1 
ATOM   10801 C  CD  . LYS C 2 361 ? 177.057 142.209 159.147 1.00 63.62  ? 361 LYS C CD  1 
ATOM   10802 C  CE  . LYS C 2 361 ? 175.944 141.750 160.071 1.00 63.62  ? 361 LYS C CE  1 
ATOM   10803 N  NZ  . LYS C 2 361 ? 176.478 141.108 161.301 1.00 63.62  ? 361 LYS C NZ  1 
ATOM   10804 N  N   . ILE C 2 362 ? 176.359 138.701 154.875 1.00 62.09  ? 362 ILE C N   1 
ATOM   10805 C  CA  . ILE C 2 362 ? 175.503 137.875 154.028 1.00 62.09  ? 362 ILE C CA  1 
ATOM   10806 C  C   . ILE C 2 362 ? 176.190 136.553 153.713 1.00 62.09  ? 362 ILE C C   1 
ATOM   10807 O  O   . ILE C 2 362 ? 175.584 135.481 153.818 1.00 62.09  ? 362 ILE C O   1 
ATOM   10808 C  CB  . ILE C 2 362 ? 175.114 138.628 152.742 1.00 62.09  ? 362 ILE C CB  1 
ATOM   10809 C  CG1 . ILE C 2 362 ? 174.401 139.935 153.074 1.00 62.09  ? 362 ILE C CG1 1 
ATOM   10810 C  CG2 . ILE C 2 362 ? 174.201 137.772 151.892 1.00 62.09  ? 362 ILE C CG2 1 
ATOM   10811 C  CD1 . ILE C 2 362 ? 173.104 139.749 153.801 1.00 62.09  ? 362 ILE C CD1 1 
ATOM   10812 N  N   . LYS C 2 363 ? 177.474 136.606 153.348 1.00 63.89  ? 363 LYS C N   1 
ATOM   10813 C  CA  . LYS C 2 363 ? 178.188 135.390 152.972 1.00 63.89  ? 363 LYS C CA  1 
ATOM   10814 C  C   . LYS C 2 363 ? 178.278 134.414 154.138 1.00 63.89  ? 363 LYS C C   1 
ATOM   10815 O  O   . LYS C 2 363 ? 178.166 133.197 153.947 1.00 63.89  ? 363 LYS C O   1 
ATOM   10816 C  CB  . LYS C 2 363 ? 179.584 135.739 152.456 1.00 63.89  ? 363 LYS C CB  1 
ATOM   10817 C  CG  . LYS C 2 363 ? 180.372 134.543 151.951 1.00 63.89  ? 363 LYS C CG  1 
ATOM   10818 C  CD  . LYS C 2 363 ? 181.694 134.964 151.336 1.00 63.89  ? 363 LYS C CD  1 
ATOM   10819 C  CE  . LYS C 2 363 ? 182.687 135.379 152.404 1.00 63.89  ? 363 LYS C CE  1 
ATOM   10820 N  NZ  . LYS C 2 363 ? 184.026 135.671 151.828 1.00 63.89  ? 363 LYS C NZ  1 
ATOM   10821 N  N   . GLN C 2 364 ? 178.475 134.925 155.355 1.00 65.67  ? 364 GLN C N   1 
ATOM   10822 C  CA  . GLN C 2 364 ? 178.532 134.040 156.514 1.00 65.67  ? 364 GLN C CA  1 
ATOM   10823 C  C   . GLN C 2 364 ? 177.166 133.440 156.814 1.00 65.67  ? 364 GLN C C   1 
ATOM   10824 O  O   . GLN C 2 364 ? 177.071 132.286 157.250 1.00 65.67  ? 364 GLN C O   1 
ATOM   10825 C  CB  . GLN C 2 364 ? 179.073 134.786 157.731 1.00 65.67  ? 364 GLN C CB  1 
ATOM   10826 C  CG  . GLN C 2 364 ? 180.518 135.213 157.580 1.00 65.67  ? 364 GLN C CG  1 
ATOM   10827 C  CD  . GLN C 2 364 ? 181.457 134.032 157.456 1.00 65.67  ? 364 GLN C CD  1 
ATOM   10828 O  OE1 . GLN C 2 364 ? 181.277 133.010 158.118 1.00 65.67  ? 364 GLN C OE1 1 
ATOM   10829 N  NE2 . GLN C 2 364 ? 182.466 134.164 156.603 1.00 65.67  ? 364 GLN C NE2 1 
ATOM   10830 N  N   . ARG C 2 365 ? 176.094 134.205 156.588 1.00 63.13  ? 365 ARG C N   1 
ATOM   10831 C  CA  . ARG C 2 365 ? 174.765 133.610 156.679 1.00 63.13  ? 365 ARG C CA  1 
ATOM   10832 C  C   . ARG C 2 365 ? 174.603 132.476 155.674 1.00 63.13  ? 365 ARG C C   1 
ATOM   10833 O  O   . ARG C 2 365 ? 174.057 131.415 156.004 1.00 63.13  ? 365 ARG C O   1 
ATOM   10834 C  CB  . ARG C 2 365 ? 173.688 134.670 156.468 1.00 63.13  ? 365 ARG C CB  1 
ATOM   10835 C  CG  . ARG C 2 365 ? 172.279 134.109 156.509 1.00 63.13  ? 365 ARG C CG  1 
ATOM   10836 C  CD  . ARG C 2 365 ? 171.951 133.519 157.868 1.00 63.13  ? 365 ARG C CD  1 
ATOM   10837 N  NE  . ARG C 2 365 ? 171.988 134.517 158.931 1.00 63.13  ? 365 ARG C NE  1 
ATOM   10838 C  CZ  . ARG C 2 365 ? 170.964 135.301 159.251 1.00 63.13  ? 365 ARG C CZ  1 
ATOM   10839 N  NH1 . ARG C 2 365 ? 169.820 135.203 158.589 1.00 63.13  ? 365 ARG C NH1 1 
ATOM   10840 N  NH2 . ARG C 2 365 ? 171.083 136.181 160.235 1.00 63.13  ? 365 ARG C NH2 1 
ATOM   10841 N  N   . LEU C 2 366 ? 175.087 132.675 154.444 1.00 62.08  ? 366 LEU C N   1 
ATOM   10842 C  CA  . LEU C 2 366 ? 174.969 131.629 153.433 1.00 62.08  ? 366 LEU C CA  1 
ATOM   10843 C  C   . LEU C 2 366 ? 175.755 130.385 153.823 1.00 62.08  ? 366 LEU C C   1 
ATOM   10844 O  O   . LEU C 2 366 ? 175.236 129.269 153.730 1.00 62.08  ? 366 LEU C O   1 
ATOM   10845 C  CB  . LEU C 2 366 ? 175.422 132.142 152.067 1.00 62.08  ? 366 LEU C CB  1 
ATOM   10846 C  CG  . LEU C 2 366 ? 174.327 132.771 151.204 1.00 62.08  ? 366 LEU C CG  1 
ATOM   10847 C  CD1 . LEU C 2 366 ? 173.232 131.750 151.000 1.00 62.08  ? 366 LEU C CD1 1 
ATOM   10848 C  CD2 . LEU C 2 366 ? 173.761 134.037 151.795 1.00 62.08  ? 366 LEU C CD2 1 
ATOM   10849 N  N   . PHE C 2 367 ? 177.008 130.551 154.256 1.00 65.32  ? 367 PHE C N   1 
ATOM   10850 C  CA  . PHE C 2 367 ? 177.772 129.398 154.723 1.00 65.32  ? 367 PHE C CA  1 
ATOM   10851 C  C   . PHE C 2 367 ? 177.051 128.687 155.859 1.00 65.32  ? 367 PHE C C   1 
ATOM   10852 O  O   . PHE C 2 367 ? 177.011 127.450 155.906 1.00 65.32  ? 367 PHE C O   1 
ATOM   10853 C  CB  . PHE C 2 367 ? 179.168 129.826 155.170 1.00 65.32  ? 367 PHE C CB  1 
ATOM   10854 C  CG  . PHE C 2 367 ? 180.077 130.215 154.043 1.00 65.32  ? 367 PHE C CG  1 
ATOM   10855 C  CD1 . PHE C 2 367 ? 179.742 129.931 152.734 1.00 65.32  ? 367 PHE C CD1 1 
ATOM   10856 C  CD2 . PHE C 2 367 ? 181.282 130.843 154.297 1.00 65.32  ? 367 PHE C CD2 1 
ATOM   10857 C  CE1 . PHE C 2 367 ? 180.583 130.282 151.701 1.00 65.32  ? 367 PHE C CE1 1 
ATOM   10858 C  CE2 . PHE C 2 367 ? 182.126 131.194 153.267 1.00 65.32  ? 367 PHE C CE2 1 
ATOM   10859 C  CZ  . PHE C 2 367 ? 181.776 130.914 151.969 1.00 65.32  ? 367 PHE C CZ  1 
ATOM   10860 N  N   . GLU C 2 368 ? 176.465 129.456 156.780 1.00 68.48  ? 368 GLU C N   1 
ATOM   10861 C  CA  . GLU C 2 368 ? 175.743 128.856 157.897 1.00 68.48  ? 368 GLU C CA  1 
ATOM   10862 C  C   . GLU C 2 368 ? 174.537 128.058 157.415 1.00 68.48  ? 368 GLU C C   1 
ATOM   10863 O  O   . GLU C 2 368 ? 174.171 127.046 158.024 1.00 68.48  ? 368 GLU C O   1 
ATOM   10864 C  CB  . GLU C 2 368 ? 175.317 129.945 158.880 1.00 68.48  ? 368 GLU C CB  1 
ATOM   10865 C  CG  . GLU C 2 368 ? 174.618 129.427 160.119 1.00 68.48  ? 368 GLU C CG  1 
ATOM   10866 C  CD  . GLU C 2 368 ? 174.268 130.533 161.092 1.00 68.48  ? 368 GLU C CD  1 
ATOM   10867 O  OE1 . GLU C 2 368 ? 174.567 131.708 160.792 1.00 68.48  ? 368 GLU C OE1 1 
ATOM   10868 O  OE2 . GLU C 2 368 ? 173.694 130.228 162.158 1.00 68.48  ? 368 GLU C OE2 1 
ATOM   10869 N  N   . ASN C 2 369 ? 173.907 128.493 156.321 1.00 66.23  ? 369 ASN C N   1 
ATOM   10870 C  CA  . ASN C 2 369 ? 172.795 127.721 155.771 1.00 66.23  ? 369 ASN C CA  1 
ATOM   10871 C  C   . ASN C 2 369 ? 173.289 126.531 154.958 1.00 66.23  ? 369 ASN C C   1 
ATOM   10872 O  O   . ASN C 2 369 ? 172.542 125.571 154.740 1.00 66.23  ? 369 ASN C O   1 
ATOM   10873 C  CB  . ASN C 2 369 ? 171.899 128.611 154.911 1.00 66.23  ? 369 ASN C CB  1 
ATOM   10874 C  CG  . ASN C 2 369 ? 171.169 129.657 155.719 1.00 66.23  ? 369 ASN C CG  1 
ATOM   10875 O  OD1 . ASN C 2 369 ? 171.382 130.855 155.546 1.00 66.23  ? 369 ASN C OD1 1 
ATOM   10876 N  ND2 . ASN C 2 369 ? 170.298 129.207 156.612 1.00 66.23  ? 369 ASN C ND2 1 
ATOM   10877 N  N   . LEU C 2 370 ? 174.540 126.572 154.498 1.00 64.54  ? 370 LEU C N   1 
ATOM   10878 C  CA  . LEU C 2 370 ? 175.043 125.512 153.631 1.00 64.54  ? 370 LEU C CA  1 
ATOM   10879 C  C   . LEU C 2 370 ? 175.709 124.391 154.415 1.00 64.54  ? 370 LEU C C   1 
ATOM   10880 O  O   . LEU C 2 370 ? 175.846 123.279 153.894 1.00 64.54  ? 370 LEU C O   1 
ATOM   10881 C  CB  . LEU C 2 370 ? 176.023 126.085 152.606 1.00 64.54  ? 370 LEU C CB  1 
ATOM   10882 C  CG  . LEU C 2 370 ? 175.418 127.032 151.569 1.00 64.54  ? 370 LEU C CG  1 
ATOM   10883 C  CD1 . LEU C 2 370 ? 176.490 127.655 150.695 1.00 64.54  ? 370 LEU C CD1 1 
ATOM   10884 C  CD2 . LEU C 2 370 ? 174.397 126.306 150.730 1.00 64.54  ? 370 LEU C CD2 1 
ATOM   10885 N  N   . ARG C 2 371 ? 176.131 124.652 155.654 1.00 68.65  ? 371 ARG C N   1 
ATOM   10886 C  CA  . ARG C 2 371 ? 176.731 123.589 156.451 1.00 68.65  ? 371 ARG C CA  1 
ATOM   10887 C  C   . ARG C 2 371 ? 175.691 122.650 157.048 1.00 68.65  ? 371 ARG C C   1 
ATOM   10888 O  O   . ARG C 2 371 ? 176.064 121.692 157.733 1.00 68.65  ? 371 ARG C O   1 
ATOM   10889 C  CB  . ARG C 2 371 ? 177.588 124.179 157.571 1.00 68.65  ? 371 ARG C CB  1 
ATOM   10890 C  CG  . ARG C 2 371 ? 178.743 125.038 157.091 1.00 68.65  ? 371 ARG C CG  1 
ATOM   10891 C  CD  . ARG C 2 371 ? 179.795 124.211 156.373 1.00 68.65  ? 371 ARG C CD  1 
ATOM   10892 N  NE  . ARG C 2 371 ? 180.913 125.034 155.924 1.00 68.65  ? 371 ARG C NE  1 
ATOM   10893 C  CZ  . ARG C 2 371 ? 181.996 125.277 156.653 1.00 68.65  ? 371 ARG C CZ  1 
ATOM   10894 N  NH1 . ARG C 2 371 ? 182.107 124.757 157.867 1.00 68.65  ? 371 ARG C NH1 1 
ATOM   10895 N  NH2 . ARG C 2 371 ? 182.968 126.038 156.171 1.00 68.65  ? 371 ARG C NH2 1 
ATOM   10896 N  N   . MET C 2 372 ? 174.406 122.894 156.807 1.00 71.55  ? 372 MET C N   1 
ATOM   10897 C  CA  . MET C 2 372 ? 173.345 122.076 157.377 1.00 71.55  ? 372 MET C CA  1 
ATOM   10898 C  C   . MET C 2 372 ? 172.710 121.130 156.368 1.00 71.55  ? 372 MET C C   1 
ATOM   10899 O  O   . MET C 2 372 ? 171.726 120.462 156.703 1.00 71.55  ? 372 MET C O   1 
ATOM   10900 C  CB  . MET C 2 372 ? 172.265 122.968 157.993 1.00 71.55  ? 372 MET C CB  1 
ATOM   10901 C  CG  . MET C 2 372 ? 172.730 123.730 159.218 1.00 71.55  ? 372 MET C CG  1 
ATOM   10902 S  SD  . MET C 2 372 ? 171.445 124.774 159.923 1.00 71.55  ? 372 MET C SD  1 
ATOM   10903 C  CE  . MET C 2 372 ? 172.360 125.578 161.234 1.00 71.55  ? 372 MET C CE  1 
ATOM   10904 N  N   . LEU C 2 373 ? 173.233 121.059 155.155 1.00 69.09  ? 373 LEU C N   1 
ATOM   10905 C  CA  . LEU C 2 373 ? 172.736 120.084 154.194 1.00 69.09  ? 373 LEU C CA  1 
ATOM   10906 C  C   . LEU C 2 373 ? 173.277 118.705 154.546 1.00 69.09  ? 373 LEU C C   1 
ATOM   10907 O  O   . LEU C 2 373 ? 174.459 118.578 154.888 1.00 69.09  ? 373 LEU C O   1 
ATOM   10908 C  CB  . LEU C 2 373 ? 173.150 120.462 152.774 1.00 69.09  ? 373 LEU C CB  1 
ATOM   10909 C  CG  . LEU C 2 373 ? 172.533 121.729 152.187 1.00 69.09  ? 373 LEU C CG  1 
ATOM   10910 C  CD1 . LEU C 2 373 ? 173.131 122.034 150.827 1.00 69.09  ? 373 LEU C CD1 1 
ATOM   10911 C  CD2 . LEU C 2 373 ? 171.035 121.571 152.088 1.00 69.09  ? 373 LEU C CD2 1 
ATOM   10912 N  N   . PRO C 2 374 ? 172.459 117.656 154.482 1.00 75.01  ? 374 PRO C N   1 
ATOM   10913 C  CA  . PRO C 2 374 ? 172.993 116.305 154.681 1.00 75.01  ? 374 PRO C CA  1 
ATOM   10914 C  C   . PRO C 2 374 ? 173.992 115.960 153.588 1.00 75.01  ? 374 PRO C C   1 
ATOM   10915 O  O   . PRO C 2 374 ? 174.065 116.626 152.553 1.00 75.01  ? 374 PRO C O   1 
ATOM   10916 C  CB  . PRO C 2 374 ? 171.746 115.416 154.613 1.00 75.01  ? 374 PRO C CB  1 
ATOM   10917 C  CG  . PRO C 2 374 ? 170.764 116.204 153.812 1.00 75.01  ? 374 PRO C CG  1 
ATOM   10918 C  CD  . PRO C 2 374 ? 171.023 117.644 154.156 1.00 75.01  ? 374 PRO C CD  1 
ATOM   10919 N  N   . HIS C 2 375 ? 174.779 114.917 153.839 1.00 79.41  ? 375 HIS C N   1 
ATOM   10920 C  CA  . HIS C 2 375 ? 175.804 114.509 152.888 1.00 79.41  ? 375 HIS C CA  1 
ATOM   10921 C  C   . HIS C 2 375 ? 175.187 114.212 151.527 1.00 79.41  ? 375 HIS C C   1 
ATOM   10922 O  O   . HIS C 2 375 ? 174.543 113.177 151.330 1.00 79.41  ? 375 HIS C O   1 
ATOM   10923 C  CB  . HIS C 2 375 ? 176.556 113.285 153.405 1.00 79.41  ? 375 HIS C CB  1 
ATOM   10924 C  CG  . HIS C 2 375 ? 177.365 113.550 154.635 1.00 79.41  ? 375 HIS C CG  1 
ATOM   10925 N  ND1 . HIS C 2 375 ? 178.560 114.236 154.606 1.00 79.41  ? 375 HIS C ND1 1 
ATOM   10926 C  CD2 . HIS C 2 375 ? 177.151 113.222 155.931 1.00 79.41  ? 375 HIS C CD2 1 
ATOM   10927 C  CE1 . HIS C 2 375 ? 179.047 114.319 155.831 1.00 79.41  ? 375 HIS C CE1 1 
ATOM   10928 N  NE2 . HIS C 2 375 ? 178.212 113.711 156.654 1.00 79.41  ? 375 HIS C NE2 1 
ATOM   10929 N  N   . ALA C 2 376 ? 175.385 115.140 150.592 1.00 69.31  ? 376 ALA C N   1 
ATOM   10930 C  CA  . ALA C 2 376 ? 174.807 115.067 149.253 1.00 69.31  ? 376 ALA C CA  1 
ATOM   10931 C  C   . ALA C 2 376 ? 173.285 114.966 149.312 1.00 69.31  ? 376 ALA C C   1 
ATOM   10932 O  O   . ALA C 2 376 ? 172.596 115.964 149.530 1.00 69.31  ? 376 ALA C O   1 
ATOM   10933 C  CB  . ALA C 2 376 ? 175.392 113.891 148.479 1.00 69.31  ? 376 ALA C CB  1 
ATOM   10934 N  N   . MET D 3 105 ? 157.292 133.848 147.824 1.00 40.88  ? 1   MET D N   1 
ATOM   10935 C  CA  . MET D 3 105 ? 157.220 132.490 147.297 1.00 40.88  ? 1   MET D CA  1 
ATOM   10936 C  C   . MET D 3 105 ? 155.973 131.767 147.783 1.00 40.88  ? 1   MET D C   1 
ATOM   10937 O  O   . MET D 3 105 ? 155.649 131.787 148.970 1.00 40.88  ? 1   MET D O   1 
ATOM   10938 C  CB  . MET D 3 105 ? 158.473 131.702 147.680 1.00 40.88  ? 1   MET D CB  1 
ATOM   10939 C  CG  . MET D 3 105 ? 159.735 132.155 146.962 1.00 40.88  ? 1   MET D CG  1 
ATOM   10940 S  SD  . MET D 3 105 ? 159.655 131.855 145.187 1.00 40.88  ? 1   MET D SD  1 
ATOM   10941 C  CE  . MET D 3 105 ? 159.287 133.492 144.570 1.00 40.88  ? 1   MET D CE  1 
ATOM   10942 N  N   . ARG D 3 106 ? 155.284 131.121 146.847 1.00 26.56  ? 2   ARG D N   1 
ATOM   10943 C  CA  . ARG D 3 106 ? 154.019 130.464 147.138 1.00 26.56  ? 2   ARG D CA  1 
ATOM   10944 C  C   . ARG D 3 106 ? 154.191 128.952 147.141 1.00 26.56  ? 2   ARG D C   1 
ATOM   10945 O  O   . ARG D 3 106 ? 154.985 128.400 146.375 1.00 26.56  ? 2   ARG D O   1 
ATOM   10946 C  CB  . ARG D 3 106 ? 152.969 130.878 146.108 1.00 26.56  ? 2   ARG D CB  1 
ATOM   10947 C  CG  . ARG D 3 106 ? 152.598 132.350 146.184 1.00 26.56  ? 2   ARG D CG  1 
ATOM   10948 C  CD  . ARG D 3 106 ? 151.676 132.761 145.050 1.00 26.56  ? 2   ARG D CD  1 
ATOM   10949 N  NE  . ARG D 3 106 ? 152.363 132.720 143.763 1.00 26.56  ? 2   ARG D NE  1 
ATOM   10950 C  CZ  . ARG D 3 106 ? 151.774 132.938 142.593 1.00 26.56  ? 2   ARG D CZ  1 
ATOM   10951 N  NH1 . ARG D 3 106 ? 150.480 133.222 142.543 1.00 26.56  ? 2   ARG D NH1 1 
ATOM   10952 N  NH2 . ARG D 3 106 ? 152.479 132.878 141.472 1.00 26.56  ? 2   ARG D NH2 1 
ATOM   10953 N  N   . VAL D 3 107 ? 153.441 128.283 148.014 1.00 17.14  ? 3   VAL D N   1 
ATOM   10954 C  CA  . VAL D 3 107 ? 153.514 126.836 148.182 1.00 17.14  ? 3   VAL D CA  1 
ATOM   10955 C  C   . VAL D 3 107 ? 152.119 126.260 147.993 1.00 17.14  ? 3   VAL D C   1 
ATOM   10956 O  O   . VAL D 3 107 ? 151.143 126.794 148.532 1.00 17.14  ? 3   VAL D O   1 
ATOM   10957 C  CB  . VAL D 3 107 ? 154.088 126.453 149.559 1.00 17.14  ? 3   VAL D CB  1 
ATOM   10958 C  CG1 . VAL D 3 107 ? 154.051 124.946 149.757 1.00 17.14  ? 3   VAL D CG1 1 
ATOM   10959 C  CG2 . VAL D 3 107 ? 155.508 126.972 149.702 1.00 17.14  ? 3   VAL D CG2 1 
ATOM   10960 N  N   . GLY D 3 108 ? 152.027 125.178 147.226 1.00 16.39  ? 4   GLY D N   1 
ATOM   10961 C  CA  . GLY D 3 108 ? 150.768 124.520 146.985 1.00 16.39  ? 4   GLY D CA  1 
ATOM   10962 C  C   . GLY D 3 108 ? 150.877 123.462 145.909 1.00 16.39  ? 4   GLY D C   1 
ATOM   10963 O  O   . GLY D 3 108 ? 151.972 123.098 145.470 1.00 16.39  ? 4   GLY D O   1 
ATOM   10964 N  N   . PRO D 3 109 ? 149.735 122.932 145.468 1.00 17.01  ? 5   PRO D N   1 
ATOM   10965 C  CA  . PRO D 3 109 ? 149.766 121.943 144.381 1.00 17.01  ? 5   PRO D CA  1 
ATOM   10966 C  C   . PRO D 3 109 ? 149.908 122.557 143.000 1.00 17.01  ? 5   PRO D C   1 
ATOM   10967 O  O   . PRO D 3 109 ? 150.601 121.978 142.155 1.00 17.01  ? 5   PRO D O   1 
ATOM   10968 C  CB  . PRO D 3 109 ? 148.428 121.209 144.538 1.00 17.01  ? 5   PRO D CB  1 
ATOM   10969 C  CG  . PRO D 3 109 ? 147.532 122.209 145.179 1.00 17.01  ? 5   PRO D CG  1 
ATOM   10970 C  CD  . PRO D 3 109 ? 148.401 123.044 146.083 1.00 17.01  ? 5   PRO D CD  1 
ATOM   10971 N  N   . GLN D 3 110 ? 149.287 123.707 142.738 1.00 19.58  ? 6   GLN D N   1 
ATOM   10972 C  CA  . GLN D 3 110 ? 149.362 124.320 141.416 1.00 19.58  ? 6   GLN D CA  1 
ATOM   10973 C  C   . GLN D 3 110 ? 150.479 125.349 141.295 1.00 19.58  ? 6   GLN D C   1 
ATOM   10974 O  O   . GLN D 3 110 ? 150.424 126.194 140.395 1.00 19.58  ? 6   GLN D O   1 
ATOM   10975 C  CB  . GLN D 3 110 ? 148.021 124.971 141.051 1.00 19.58  ? 6   GLN D CB  1 
ATOM   10976 C  CG  . GLN D 3 110 ? 147.691 126.240 141.828 1.00 19.58  ? 6   GLN D CG  1 
ATOM   10977 C  CD  . GLN D 3 110 ? 146.987 125.965 143.138 1.00 19.58  ? 6   GLN D CD  1 
ATOM   10978 O  OE1 . GLN D 3 110 ? 146.982 124.839 143.628 1.00 19.58  ? 6   GLN D OE1 1 
ATOM   10979 N  NE2 . GLN D 3 110 ? 146.386 126.998 143.715 1.00 19.58  ? 6   GLN D NE2 1 
ATOM   10980 N  N   . TYR D 3 111 ? 151.489 125.299 142.158 1.00 16.56  ? 7   TYR D N   1 
ATOM   10981 C  CA  . TYR D 3 111 ? 152.579 126.266 142.123 1.00 16.56  ? 7   TYR D CA  1 
ATOM   10982 C  C   . TYR D 3 111 ? 153.931 125.645 141.813 1.00 16.56  ? 7   TYR D C   1 
ATOM   10983 O  O   . TYR D 3 111 ? 154.681 126.194 141.004 1.00 16.56  ? 7   TYR D O   1 
ATOM   10984 C  CB  . TYR D 3 111 ? 152.655 127.022 143.456 1.00 16.56  ? 7   TYR D CB  1 
ATOM   10985 C  CG  . TYR D 3 111 ? 151.458 127.906 143.716 1.00 16.56  ? 7   TYR D CG  1 
ATOM   10986 C  CD1 . TYR D 3 111 ? 151.346 129.148 143.112 1.00 16.56  ? 7   TYR D CD1 1 
ATOM   10987 C  CD2 . TYR D 3 111 ? 150.440 127.499 144.565 1.00 16.56  ? 7   TYR D CD2 1 
ATOM   10988 C  CE1 . TYR D 3 111 ? 150.254 129.960 143.345 1.00 16.56  ? 7   TYR D CE1 1 
ATOM   10989 C  CE2 . TYR D 3 111 ? 149.344 128.305 144.806 1.00 16.56  ? 7   TYR D CE2 1 
ATOM   10990 C  CZ  . TYR D 3 111 ? 149.256 129.534 144.194 1.00 16.56  ? 7   TYR D CZ  1 
ATOM   10991 O  OH  . TYR D 3 111 ? 148.166 130.340 144.430 1.00 16.56  ? 7   TYR D OH  1 
ATOM   10992 N  N   . GLN D 3 112 ? 154.266 124.519 142.430 1.00 10.27  ? 8   GLN D N   1 
ATOM   10993 C  CA  . GLN D 3 112 ? 155.533 123.855 142.173 1.00 10.27  ? 8   GLN D CA  1 
ATOM   10994 C  C   . GLN D 3 112 ? 155.394 122.803 141.078 1.00 10.27  ? 8   GLN D C   1 
ATOM   10995 O  O   . GLN D 3 112 ? 154.292 122.411 140.687 1.00 10.27  ? 8   GLN D O   1 
ATOM   10996 C  CB  . GLN D 3 112 ? 156.078 123.211 143.449 1.00 10.27  ? 8   GLN D CB  1 
ATOM   10997 C  CG  . GLN D 3 112 ? 156.641 124.200 144.451 1.00 10.27  ? 8   GLN D CG  1 
ATOM   10998 C  CD  . GLN D 3 112 ? 155.574 124.880 145.269 1.00 10.27  ? 8   GLN D CD  1 
ATOM   10999 O  OE1 . GLN D 3 112 ? 154.443 124.408 145.347 1.00 10.27  ? 8   GLN D OE1 1 
ATOM   11000 N  NE2 . GLN D 3 112 ? 155.925 126.004 145.883 1.00 10.27  ? 8   GLN D NE2 1 
ATOM   11001 N  N   . ALA D 3 113 ? 156.542 122.353 140.582 1.00 10.92  ? 9   ALA D N   1 
ATOM   11002 C  CA  . ALA D 3 113 ? 156.606 121.316 139.566 1.00 10.92  ? 9   ALA D CA  1 
ATOM   11003 C  C   . ALA D 3 113 ? 156.646 119.940 140.216 1.00 10.92  ? 9   ALA D C   1 
ATOM   11004 O  O   . ALA D 3 113 ? 157.232 119.752 141.286 1.00 10.92  ? 9   ALA D O   1 
ATOM   11005 C  CB  . ALA D 3 113 ? 157.835 121.503 138.678 1.00 10.92  ? 9   ALA D CB  1 
ATOM   11006 N  N   . VAL D 3 114 ? 156.014 118.974 139.555 1.00 6.64   ? 10  VAL D N   1 
ATOM   11007 C  CA  . VAL D 3 114 ? 155.948 117.603 140.049 1.00 6.64   ? 10  VAL D CA  1 
ATOM   11008 C  C   . VAL D 3 114 ? 157.215 116.897 139.577 1.00 6.64   ? 10  VAL D C   1 
ATOM   11009 O  O   . VAL D 3 114 ? 157.284 116.399 138.453 1.00 6.64   ? 10  VAL D O   1 
ATOM   11010 C  CB  . VAL D 3 114 ? 154.684 116.889 139.568 1.00 6.64   ? 10  VAL D CB  1 
ATOM   11011 C  CG1 . VAL D 3 114 ? 154.664 115.447 140.056 1.00 6.64   ? 10  VAL D CG1 1 
ATOM   11012 C  CG2 . VAL D 3 114 ? 153.445 117.635 140.036 1.00 6.64   ? 10  VAL D CG2 1 
ATOM   11013 N  N   . VAL D 3 115 ? 158.227 116.863 140.438 1.00 13.44  ? 11  VAL D N   1 
ATOM   11014 C  CA  . VAL D 3 115 ? 159.499 116.231 140.097 1.00 13.44  ? 11  VAL D CA  1 
ATOM   11015 C  C   . VAL D 3 115 ? 159.356 114.718 140.215 1.00 13.44  ? 11  VAL D C   1 
ATOM   11016 O  O   . VAL D 3 115 ? 158.806 114.218 141.208 1.00 13.44  ? 11  VAL D O   1 
ATOM   11017 C  CB  . VAL D 3 115 ? 160.643 116.760 140.978 1.00 13.44  ? 11  VAL D CB  1 
ATOM   11018 C  CG1 . VAL D 3 115 ? 160.884 118.233 140.700 1.00 13.44  ? 11  VAL D CG1 1 
ATOM   11019 C  CG2 . VAL D 3 115 ? 160.332 116.552 142.451 1.00 13.44  ? 11  VAL D CG2 1 
ATOM   11020 N  N   . PRO D 3 116 ? 159.802 113.956 139.222 1.00 16.99  ? 12  PRO D N   1 
ATOM   11021 C  CA  . PRO D 3 116 ? 159.774 112.498 139.352 1.00 16.99  ? 12  PRO D CA  1 
ATOM   11022 C  C   . PRO D 3 116 ? 160.930 111.999 140.204 1.00 16.99  ? 12  PRO D C   1 
ATOM   11023 O  O   . PRO D 3 116 ? 162.095 112.334 139.973 1.00 16.99  ? 12  PRO D O   1 
ATOM   11024 C  CB  . PRO D 3 116 ? 159.896 112.012 137.904 1.00 16.99  ? 12  PRO D CB  1 
ATOM   11025 C  CG  . PRO D 3 116 ? 160.635 113.112 137.209 1.00 16.99  ? 12  PRO D CG  1 
ATOM   11026 C  CD  . PRO D 3 116 ? 160.195 114.390 137.869 1.00 16.99  ? 12  PRO D CD  1 
ATOM   11027 N  N   . ASP D 3 117 ? 160.592 111.193 141.206 1.00 27.23  ? 13  ASP D N   1 
ATOM   11028 C  CA  . ASP D 3 117 ? 161.598 110.628 142.094 1.00 27.23  ? 13  ASP D CA  1 
ATOM   11029 C  C   . ASP D 3 117 ? 162.527 109.694 141.328 1.00 27.23  ? 13  ASP D C   1 
ATOM   11030 O  O   . ASP D 3 117 ? 162.208 109.220 140.234 1.00 27.23  ? 13  ASP D O   1 
ATOM   11031 C  CB  . ASP D 3 117 ? 160.939 109.888 143.257 1.00 27.23  ? 13  ASP D CB  1 
ATOM   11032 C  CG  . ASP D 3 117 ? 160.290 110.832 144.252 1.00 27.23  ? 13  ASP D CG  1 
ATOM   11033 O  OD1 . ASP D 3 117 ? 160.775 111.975 144.390 1.00 27.23  ? 13  ASP D OD1 1 
ATOM   11034 O  OD2 . ASP D 3 117 ? 159.297 110.433 144.897 1.00 27.23  ? 13  ASP D OD2 1 
ATOM   11035 N  N   . PHE D 3 118 ? 163.687 109.426 141.921 1.00 33.36  ? 14  PHE D N   1 
ATOM   11036 C  CA  . PHE D 3 118 ? 164.804 108.817 141.213 1.00 33.36  ? 14  PHE D CA  1 
ATOM   11037 C  C   . PHE D 3 118 ? 164.829 107.313 141.455 1.00 33.36  ? 14  PHE D C   1 
ATOM   11038 O  O   . PHE D 3 118 ? 164.954 106.865 142.600 1.00 33.36  ? 14  PHE D O   1 
ATOM   11039 C  CB  . PHE D 3 118 ? 166.123 109.449 141.652 1.00 33.36  ? 14  PHE D CB  1 
ATOM   11040 C  CG  . PHE D 3 118 ? 167.306 108.998 140.848 1.00 33.36  ? 14  PHE D CG  1 
ATOM   11041 C  CD1 . PHE D 3 118 ? 167.525 109.501 139.579 1.00 33.36  ? 14  PHE D CD1 1 
ATOM   11042 C  CD2 . PHE D 3 118 ? 168.195 108.071 141.357 1.00 33.36  ? 14  PHE D CD2 1 
ATOM   11043 C  CE1 . PHE D 3 118 ? 168.611 109.092 138.834 1.00 33.36  ? 14  PHE D CE1 1 
ATOM   11044 C  CE2 . PHE D 3 118 ? 169.286 107.660 140.615 1.00 33.36  ? 14  PHE D CE2 1 
ATOM   11045 C  CZ  . PHE D 3 118 ? 169.491 108.172 139.353 1.00 33.36  ? 14  PHE D CZ  1 
ATOM   11046 N  N   . ASP D 3 119 ? 164.719 106.543 140.376 1.00 44.08  ? 15  ASP D N   1 
ATOM   11047 C  CA  . ASP D 3 119 ? 164.910 105.093 140.404 1.00 44.08  ? 15  ASP D CA  1 
ATOM   11048 C  C   . ASP D 3 119 ? 165.953 104.749 139.350 1.00 44.08  ? 15  ASP D C   1 
ATOM   11049 O  O   . ASP D 3 119 ? 165.706 104.939 138.146 1.00 44.08  ? 15  ASP D O   1 
ATOM   11050 C  CB  . ASP D 3 119 ? 163.601 104.354 140.136 1.00 44.08  ? 15  ASP D CB  1 
ATOM   11051 C  CG  . ASP D 3 119 ? 163.704 102.862 140.402 1.00 44.08  ? 15  ASP D CG  1 
ATOM   11052 O  OD1 . ASP D 3 119 ? 164.797 102.391 140.780 1.00 44.08  ? 15  ASP D OD1 1 
ATOM   11053 O  OD2 . ASP D 3 119 ? 162.688 102.157 140.231 1.00 44.08  ? 15  ASP D OD2 1 
ATOM   11054 N  N   . PRO D 3 120 ? 167.128 104.250 139.745 1.00 46.32  ? 16  PRO D N   1 
ATOM   11055 C  CA  . PRO D 3 120 ? 168.203 104.036 138.760 1.00 46.32  ? 16  PRO D CA  1 
ATOM   11056 C  C   . PRO D 3 120 ? 167.845 103.058 137.654 1.00 46.32  ? 16  PRO D C   1 
ATOM   11057 O  O   . PRO D 3 120 ? 168.498 103.068 136.601 1.00 46.32  ? 16  PRO D O   1 
ATOM   11058 C  CB  . PRO D 3 120 ? 169.361 103.512 139.621 1.00 46.32  ? 16  PRO D CB  1 
ATOM   11059 C  CG  . PRO D 3 120 ? 169.069 104.024 140.997 1.00 46.32  ? 16  PRO D CG  1 
ATOM   11060 C  CD  . PRO D 3 120 ? 167.578 103.989 141.122 1.00 46.32  ? 16  PRO D CD  1 
ATOM   11061 N  N   . ALA D 3 121 ? 166.814 102.229 137.850 1.00 50.19  ? 17  ALA D N   1 
ATOM   11062 C  CA  . ALA D 3 121 ? 166.454 101.203 136.877 1.00 50.19  ? 17  ALA D CA  1 
ATOM   11063 C  C   . ALA D 3 121 ? 166.180 101.767 135.488 1.00 50.19  ? 17  ALA D C   1 
ATOM   11064 O  O   . ALA D 3 121 ? 166.239 101.016 134.508 1.00 50.19  ? 17  ALA D O   1 
ATOM   11065 C  CB  . ALA D 3 121 ? 165.231 100.425 137.365 1.00 50.19  ? 17  ALA D CB  1 
ATOM   11066 N  N   . LYS D 3 122 ? 165.885 103.059 135.376 1.00 58.66  ? 18  LYS D N   1 
ATOM   11067 C  CA  . LYS D 3 122 ? 165.647 103.690 134.086 1.00 58.66  ? 18  LYS D CA  1 
ATOM   11068 C  C   . LYS D 3 122 ? 166.772 104.624 133.662 1.00 58.66  ? 18  LYS D C   1 
ATOM   11069 O  O   . LYS D 3 122 ? 166.499 105.659 133.046 1.00 58.66  ? 18  LYS D O   1 
ATOM   11070 C  CB  . LYS D 3 122 ? 164.317 104.448 134.108 1.00 58.66  ? 18  LYS D CB  1 
ATOM   11071 C  CG  . LYS D 3 122 ? 163.105 103.533 134.180 1.00 58.66  ? 18  LYS D CG  1 
ATOM   11072 C  CD  . LYS D 3 122 ? 161.813 104.325 134.170 1.00 58.66  ? 18  LYS D CD  1 
ATOM   11073 C  CE  . LYS D 3 122 ? 160.602 103.414 134.238 1.00 58.66  ? 18  LYS D CE  1 
ATOM   11074 N  NZ  . LYS D 3 122 ? 159.332 104.190 134.227 1.00 58.66  ? 18  LYS D NZ  1 
ATOM   11075 N  N   . LEU D 3 123 ? 168.025 104.290 133.979 1.00 62.90  ? 19  LEU D N   1 
ATOM   11076 C  CA  . LEU D 3 123 ? 169.146 105.070 133.464 1.00 62.90  ? 19  LEU D CA  1 
ATOM   11077 C  C   . LEU D 3 123 ? 169.957 104.283 132.442 1.00 62.90  ? 19  LEU D C   1 
ATOM   11078 O  O   . LEU D 3 123 ? 171.191 104.267 132.516 1.00 62.90  ? 19  LEU D O   1 
ATOM   11079 C  CB  . LEU D 3 123 ? 170.048 105.529 134.610 1.00 62.90  ? 19  LEU D CB  1 
ATOM   11080 C  CG  . LEU D 3 123 ? 169.668 106.804 135.369 1.00 62.90  ? 19  LEU D CG  1 
ATOM   11081 C  CD1 . LEU D 3 123 ? 168.427 106.609 136.218 1.00 62.90  ? 19  LEU D CD1 1 
ATOM   11082 C  CD2 . LEU D 3 123 ? 170.836 107.265 136.228 1.00 62.90  ? 19  LEU D CD2 1 
ATOM   11083 N  N   . ALA D 3 124 ? 169.291 103.634 131.482 1.00 85.87  ? 20  ALA D N   1 
ATOM   11084 C  CA  . ALA D 3 124 ? 170.009 102.822 130.506 1.00 85.87  ? 20  ALA D CA  1 
ATOM   11085 C  C   . ALA D 3 124 ? 169.228 102.617 129.214 1.00 85.87  ? 20  ALA D C   1 
ATOM   11086 O  O   . ALA D 3 124 ? 169.776 102.853 128.132 1.00 85.87  ? 20  ALA D O   1 
ATOM   11087 C  CB  . ALA D 3 124 ? 170.362 101.464 131.113 1.00 85.87  ? 20  ALA D CB  1 
ATOM   11088 N  N   . ARG D 3 125 ? 167.969 102.184 129.296 1.00 105.99 ? 21  ARG D N   1 
ATOM   11089 C  CA  . ARG D 3 125 ? 167.200 101.800 128.118 1.00 105.99 ? 21  ARG D CA  1 
ATOM   11090 C  C   . ARG D 3 125 ? 166.543 102.968 127.397 1.00 105.99 ? 21  ARG D C   1 
ATOM   11091 O  O   . ARG D 3 125 ? 166.375 102.904 126.177 1.00 105.99 ? 21  ARG D O   1 
ATOM   11092 C  CB  . ARG D 3 125 ? 166.123 100.775 128.500 1.00 105.99 ? 21  ARG D CB  1 
ATOM   11093 C  CG  . ARG D 3 125 ? 165.326 100.230 127.323 1.00 105.99 ? 21  ARG D CG  1 
ATOM   11094 C  CD  . ARG D 3 125 ? 164.378 99.122  127.751 1.00 105.99 ? 21  ARG D CD  1 
ATOM   11095 N  NE  . ARG D 3 125 ? 165.098 97.916  128.150 1.00 105.99 ? 21  ARG D NE  1 
ATOM   11096 C  CZ  . ARG D 3 125 ? 164.528 96.855  128.710 1.00 105.99 ? 21  ARG D CZ  1 
ATOM   11097 N  NH1 . ARG D 3 125 ? 163.222 96.845  128.938 1.00 105.99 ? 21  ARG D NH1 1 
ATOM   11098 N  NH2 . ARG D 3 125 ? 165.263 95.802  129.041 1.00 105.99 ? 21  ARG D NH2 1 
ATOM   11099 N  N   . ARG D 3 126 ? 166.184 104.041 128.107 1.00 96.23  ? 22  ARG D N   1 
ATOM   11100 C  CA  . ARG D 3 126 ? 165.545 105.180 127.453 1.00 96.23  ? 22  ARG D CA  1 
ATOM   11101 C  C   . ARG D 3 126 ? 166.514 105.906 126.525 1.00 96.23  ? 22  ARG D C   1 
ATOM   11102 O  O   . ARG D 3 126 ? 166.106 106.780 125.750 1.00 96.23  ? 22  ARG D O   1 
ATOM   11103 C  CB  . ARG D 3 126 ? 164.985 106.148 128.497 1.00 96.23  ? 22  ARG D CB  1 
ATOM   11104 C  CG  . ARG D 3 126 ? 163.753 105.666 129.243 1.00 96.23  ? 22  ARG D CG  1 
ATOM   11105 C  CD  . ARG D 3 126 ? 163.303 106.721 130.243 1.00 96.23  ? 22  ARG D CD  1 
ATOM   11106 N  NE  . ARG D 3 126 ? 162.068 106.356 130.929 1.00 96.23  ? 22  ARG D NE  1 
ATOM   11107 C  CZ  . ARG D 3 126 ? 161.505 107.084 131.889 1.00 96.23  ? 22  ARG D CZ  1 
ATOM   11108 N  NH1 . ARG D 3 126 ? 162.072 108.214 132.287 1.00 96.23  ? 22  ARG D NH1 1 
ATOM   11109 N  NH2 . ARG D 3 126 ? 160.375 106.681 132.456 1.00 96.23  ? 22  ARG D NH2 1 
ATOM   11110 N  N   . SER D 3 127 ? 167.800 105.541 126.572 1.00 107.45 ? 23  SER D N   1 
ATOM   11111 C  CA  . SER D 3 127 ? 168.823 106.275 125.830 1.00 107.45 ? 23  SER D CA  1 
ATOM   11112 C  C   . SER D 3 127 ? 168.575 106.238 124.326 1.00 107.45 ? 23  SER D C   1 
ATOM   11113 O  O   . SER D 3 127 ? 169.195 106.998 123.573 1.00 107.45 ? 23  SER D O   1 
ATOM   11114 C  CB  . SER D 3 127 ? 170.207 105.714 126.156 1.00 107.45 ? 23  SER D CB  1 
ATOM   11115 O  OG  . SER D 3 127 ? 170.347 104.389 125.673 1.00 107.45 ? 23  SER D OG  1 
ATOM   11116 N  N   . GLN D 3 128 ? 167.681 105.362 123.866 1.00 106.88 ? 24  GLN D N   1 
ATOM   11117 C  CA  . GLN D 3 128 ? 167.329 105.335 122.453 1.00 106.88 ? 24  GLN D CA  1 
ATOM   11118 C  C   . GLN D 3 128 ? 165.842 105.553 122.209 1.00 106.88 ? 24  GLN D C   1 
ATOM   11119 O  O   . GLN D 3 128 ? 165.427 105.613 121.046 1.00 106.88 ? 24  GLN D O   1 
ATOM   11120 C  CB  . GLN D 3 128 ? 167.767 104.011 121.825 1.00 106.88 ? 24  GLN D CB  1 
ATOM   11121 C  CG  . GLN D 3 128 ? 169.273 103.834 121.752 1.00 106.88 ? 24  GLN D CG  1 
ATOM   11122 C  CD  . GLN D 3 128 ? 169.674 102.511 121.131 1.00 106.88 ? 24  GLN D CD  1 
ATOM   11123 O  OE1 . GLN D 3 128 ? 168.824 101.682 120.806 1.00 106.88 ? 24  GLN D OE1 1 
ATOM   11124 N  NE2 . GLN D 3 128 ? 170.975 102.307 120.964 1.00 106.88 ? 24  GLN D NE2 1 
ATOM   11125 N  N   . GLU D 3 129 ? 165.033 105.674 123.264 1.00 101.67 ? 25  GLU D N   1 
ATOM   11126 C  CA  . GLU D 3 129 ? 163.603 105.897 123.107 1.00 101.67 ? 25  GLU D CA  1 
ATOM   11127 C  C   . GLU D 3 129 ? 163.259 107.312 122.669 1.00 101.67 ? 25  GLU D C   1 
ATOM   11128 O  O   . GLU D 3 129 ? 162.138 107.540 122.201 1.00 101.67 ? 25  GLU D O   1 
ATOM   11129 C  CB  . GLU D 3 129 ? 162.863 105.578 124.415 1.00 101.67 ? 25  GLU D CB  1 
ATOM   11130 C  CG  . GLU D 3 129 ? 162.869 104.103 124.783 1.00 101.67 ? 25  GLU D CG  1 
ATOM   11131 C  CD  . GLU D 3 129 ? 162.108 103.816 126.061 1.00 101.67 ? 25  GLU D CD  1 
ATOM   11132 O  OE1 . GLU D 3 129 ? 161.678 104.779 126.730 1.00 101.67 ? 25  GLU D OE1 1 
ATOM   11133 O  OE2 . GLU D 3 129 ? 161.937 102.625 126.396 1.00 101.67 ? 25  GLU D OE2 1 
ATOM   11134 N  N   . ARG D 3 130 ? 164.181 108.259 122.802 1.00 94.20  ? 26  ARG D N   1 
ATOM   11135 C  CA  . ARG D 3 130 ? 163.967 109.633 122.374 1.00 94.20  ? 26  ARG D CA  1 
ATOM   11136 C  C   . ARG D 3 130 ? 165.186 110.095 121.587 1.00 94.20  ? 26  ARG D C   1 
ATOM   11137 O  O   . ARG D 3 130 ? 166.240 110.373 122.169 1.00 94.20  ? 26  ARG D O   1 
ATOM   11138 C  CB  . ARG D 3 130 ? 163.712 110.540 123.579 1.00 94.20  ? 26  ARG D CB  1 
ATOM   11139 C  CG  . ARG D 3 130 ? 163.276 111.951 123.231 1.00 94.20  ? 26  ARG D CG  1 
ATOM   11140 C  CD  . ARG D 3 130 ? 162.872 112.713 124.484 1.00 94.20  ? 26  ARG D CD  1 
ATOM   11141 N  NE  . ARG D 3 130 ? 162.436 114.074 124.184 1.00 94.20  ? 26  ARG D NE  1 
ATOM   11142 C  CZ  . ARG D 3 130 ? 161.992 114.935 125.094 1.00 94.20  ? 26  ARG D CZ  1 
ATOM   11143 N  NH1 . ARG D 3 130 ? 161.920 114.578 126.369 1.00 94.20  ? 26  ARG D NH1 1 
ATOM   11144 N  NH2 . ARG D 3 130 ? 161.617 116.152 124.729 1.00 94.20  ? 26  ARG D NH2 1 
ATOM   11145 N  N   . ASP D 3 131 ? 165.039 110.170 120.267 1.00 92.74  ? 27  ASP D N   1 
ATOM   11146 C  CA  . ASP D 3 131 ? 166.169 110.377 119.373 1.00 92.74  ? 27  ASP D CA  1 
ATOM   11147 C  C   . ASP D 3 131 ? 166.698 111.803 119.461 1.00 92.74  ? 27  ASP D C   1 
ATOM   11148 O  O   . ASP D 3 131 ? 166.300 112.590 120.325 1.00 92.74  ? 27  ASP D O   1 
ATOM   11149 C  CB  . ASP D 3 131 ? 165.767 110.070 117.930 1.00 92.74  ? 27  ASP D CB  1 
ATOM   11150 C  CG  . ASP D 3 131 ? 165.462 108.602 117.709 1.00 92.74  ? 27  ASP D CG  1 
ATOM   11151 O  OD1 . ASP D 3 131 ? 166.049 107.756 118.416 1.00 92.74  ? 27  ASP D OD1 1 
ATOM   11152 O  OD2 . ASP D 3 131 ? 164.631 108.294 116.829 1.00 92.74  ? 27  ASP D OD2 1 
ATOM   11153 N  N   . ASN D 3 132 ? 167.613 112.127 118.548 1.00 84.88  ? 28  ASN D N   1 
ATOM   11154 C  CA  . ASN D 3 132 ? 168.146 113.481 118.456 1.00 84.88  ? 28  ASN D CA  1 
ATOM   11155 C  C   . ASN D 3 132 ? 167.030 114.442 118.068 1.00 84.88  ? 28  ASN D C   1 
ATOM   11156 O  O   . ASN D 3 132 ? 166.325 114.222 117.078 1.00 84.88  ? 28  ASN D O   1 
ATOM   11157 C  CB  . ASN D 3 132 ? 169.282 113.539 117.437 1.00 84.88  ? 28  ASN D CB  1 
ATOM   11158 C  CG  . ASN D 3 132 ? 170.537 112.842 117.921 1.00 84.88  ? 28  ASN D CG  1 
ATOM   11159 O  OD1 . ASN D 3 132 ? 170.923 112.969 119.083 1.00 84.88  ? 28  ASN D OD1 1 
ATOM   11160 N  ND2 . ASN D 3 132 ? 171.185 112.103 117.028 1.00 84.88  ? 28  ASN D ND2 1 
ATOM   11161 N  N   . LEU D 3 133 ? 166.868 115.504 118.850 1.00 50.11  ? 29  LEU D N   1 
ATOM   11162 C  CA  . LEU D 3 133 ? 165.821 116.495 118.607 1.00 50.11  ? 29  LEU D CA  1 
ATOM   11163 C  C   . LEU D 3 133 ? 166.380 117.740 117.926 1.00 50.11  ? 29  LEU D C   1 
ATOM   11164 O  O   . LEU D 3 133 ? 166.874 118.663 118.571 1.00 50.11  ? 29  LEU D O   1 
ATOM   11165 C  CB  . LEU D 3 133 ? 165.132 116.846 119.920 1.00 50.11  ? 29  LEU D CB  1 
ATOM   11166 C  CG  . LEU D 3 133 ? 164.359 115.712 120.596 1.00 50.11  ? 29  LEU D CG  1 
ATOM   11167 C  CD1 . LEU D 3 133 ? 163.847 116.148 121.957 1.00 50.11  ? 29  LEU D CD1 1 
ATOM   11168 C  CD2 . LEU D 3 133 ? 163.212 115.243 119.717 1.00 50.11  ? 29  LEU D CD2 1 
ATOM   11169 N  N   . GLY D 3 134 ? 166.308 117.766 116.600 1.00 33.34  ? 30  GLY D N   1 
ATOM   11170 C  CA  . GLY D 3 134 ? 166.804 118.899 115.847 1.00 33.34  ? 30  GLY D CA  1 
ATOM   11171 C  C   . GLY D 3 134 ? 167.782 118.457 114.785 1.00 33.34  ? 30  GLY D C   1 
ATOM   11172 O  O   . GLY D 3 134 ? 168.521 117.482 114.959 1.00 33.34  ? 30  GLY D O   1 
ATOM   11173 N  N   . MET D 3 135 ? 167.779 119.194 113.678 1.00 33.38  ? 31  MET D N   1 
ATOM   11174 C  CA  . MET D 3 135 ? 168.634 118.908 112.534 1.00 33.38  ? 31  MET D CA  1 
ATOM   11175 C  C   . MET D 3 135 ? 170.073 119.244 112.897 1.00 33.38  ? 31  MET D C   1 
ATOM   11176 O  O   . MET D 3 135 ? 170.317 120.113 113.741 1.00 33.38  ? 31  MET D O   1 
ATOM   11177 C  CB  . MET D 3 135 ? 168.195 119.701 111.303 1.00 33.38  ? 31  MET D CB  1 
ATOM   11178 C  CG  . MET D 3 135 ? 166.942 119.170 110.633 1.00 33.38  ? 31  MET D CG  1 
ATOM   11179 S  SD  . MET D 3 135 ? 165.447 119.593 111.545 1.00 33.38  ? 31  MET D SD  1 
ATOM   11180 C  CE  . MET D 3 135 ? 165.295 121.331 111.139 1.00 33.38  ? 31  MET D CE  1 
ATOM   11181 N  N   . LEU D 3 136 ? 171.018 118.556 112.263 1.00 26.61  ? 32  LEU D N   1 
ATOM   11182 C  CA  . LEU D 3 136 ? 172.430 118.858 112.443 1.00 26.61  ? 32  LEU D CA  1 
ATOM   11183 C  C   . LEU D 3 136 ? 172.951 119.546 111.189 1.00 26.61  ? 32  LEU D C   1 
ATOM   11184 O  O   . LEU D 3 136 ? 173.311 118.883 110.212 1.00 26.61  ? 32  LEU D O   1 
ATOM   11185 C  CB  . LEU D 3 136 ? 173.218 117.578 112.726 1.00 26.61  ? 32  LEU D CB  1 
ATOM   11186 C  CG  . LEU D 3 136 ? 174.650 117.677 113.265 1.00 26.61  ? 32  LEU D CG  1 
ATOM   11187 C  CD1 . LEU D 3 136 ? 174.983 116.432 114.068 1.00 26.61  ? 32  LEU D CD1 1 
ATOM   11188 C  CD2 . LEU D 3 136 ? 175.685 117.887 112.174 1.00 26.61  ? 32  LEU D CD2 1 
ATOM   11189 N  N   . VAL D 3 137 ? 172.981 120.876 111.210 1.00 40.88  ? 33  VAL D N   1 
ATOM   11190 C  CA  . VAL D 3 137 ? 173.355 121.649 110.033 1.00 40.88  ? 33  VAL D CA  1 
ATOM   11191 C  C   . VAL D 3 137 ? 174.860 121.808 109.870 1.00 40.88  ? 33  VAL D C   1 
ATOM   11192 O  O   . VAL D 3 137 ? 175.315 122.098 108.752 1.00 40.88  ? 33  VAL D O   1 
ATOM   11193 C  CB  . VAL D 3 137 ? 172.675 123.033 110.036 1.00 40.88  ? 33  VAL D CB  1 
ATOM   11194 C  CG1 . VAL D 3 137 ? 171.169 122.876 109.979 1.00 40.88  ? 33  VAL D CG1 1 
ATOM   11195 C  CG2 . VAL D 3 137 ? 173.084 123.821 111.261 1.00 40.88  ? 33  VAL D CG2 1 
ATOM   11196 N  N   . TRP D 3 138 ? 175.655 121.633 110.922 1.00 33.26  ? 34  TRP D N   1 
ATOM   11197 C  CA  . TRP D 3 138 ? 177.102 121.726 110.797 1.00 33.26  ? 34  TRP D CA  1 
ATOM   11198 C  C   . TRP D 3 138 ? 177.761 120.985 111.950 1.00 33.26  ? 34  TRP D C   1 
ATOM   11199 O  O   . TRP D 3 138 ? 177.208 120.920 113.050 1.00 33.26  ? 34  TRP D O   1 
ATOM   11200 C  CB  . TRP D 3 138 ? 177.579 123.182 110.764 1.00 33.26  ? 34  TRP D CB  1 
ATOM   11201 C  CG  . TRP D 3 138 ? 179.068 123.294 110.708 1.00 33.26  ? 34  TRP D CG  1 
ATOM   11202 C  CD1 . TRP D 3 138 ? 179.894 123.684 111.717 1.00 33.26  ? 34  TRP D CD1 1 
ATOM   11203 C  CD2 . TRP D 3 138 ? 179.915 122.958 109.602 1.00 33.26  ? 34  TRP D CD2 1 
ATOM   11204 N  NE1 . TRP D 3 138 ? 181.202 123.642 111.301 1.00 33.26  ? 34  TRP D NE1 1 
ATOM   11205 C  CE2 . TRP D 3 138 ? 181.243 123.198 110.006 1.00 33.26  ? 34  TRP D CE2 1 
ATOM   11206 C  CE3 . TRP D 3 138 ? 179.679 122.492 108.307 1.00 33.26  ? 34  TRP D CE3 1 
ATOM   11207 C  CZ2 . TRP D 3 138 ? 182.330 122.982 109.163 1.00 33.26  ? 34  TRP D CZ2 1 
ATOM   11208 C  CZ3 . TRP D 3 138 ? 180.758 122.284 107.470 1.00 33.26  ? 34  TRP D CZ3 1 
ATOM   11209 C  CH2 . TRP D 3 138 ? 182.067 122.527 107.901 1.00 33.26  ? 34  TRP D CH2 1 
ATOM   11210 N  N   . SER D 3 139 ? 178.939 120.430 111.684 1.00 34.49  ? 35  SER D N   1 
ATOM   11211 C  CA  . SER D 3 139 ? 179.739 119.718 112.666 1.00 34.49  ? 35  SER D CA  1 
ATOM   11212 C  C   . SER D 3 139 ? 181.211 119.894 112.329 1.00 34.49  ? 35  SER D C   1 
ATOM   11213 O  O   . SER D 3 139 ? 181.595 119.813 111.157 1.00 34.49  ? 35  SER D O   1 
ATOM   11214 C  CB  . SER D 3 139 ? 179.397 118.221 112.703 1.00 34.49  ? 35  SER D CB  1 
ATOM   11215 O  OG  . SER D 3 139 ? 180.221 117.534 113.628 1.00 34.49  ? 35  SER D OG  1 
ATOM   11216 N  N   . PRO D 3 140 ? 182.053 120.145 113.329 1.00 36.84  ? 36  PRO D N   1 
ATOM   11217 C  CA  . PRO D 3 140 ? 183.488 120.279 113.063 1.00 36.84  ? 36  PRO D CA  1 
ATOM   11218 C  C   . PRO D 3 140 ? 184.074 118.992 112.512 1.00 36.84  ? 36  PRO D C   1 
ATOM   11219 O  O   . PRO D 3 140 ? 183.499 117.909 112.647 1.00 36.84  ? 36  PRO D O   1 
ATOM   11220 C  CB  . PRO D 3 140 ? 184.076 120.607 114.440 1.00 36.84  ? 36  PRO D CB  1 
ATOM   11221 C  CG  . PRO D 3 140 ? 182.937 121.172 115.210 1.00 36.84  ? 36  PRO D CG  1 
ATOM   11222 C  CD  . PRO D 3 140 ? 181.727 120.433 114.734 1.00 36.84  ? 36  PRO D CD  1 
ATOM   11223 N  N   . ASN D 3 141 ? 185.242 119.121 111.887 1.00 64.66  ? 37  ASN D N   1 
ATOM   11224 C  CA  . ASN D 3 141 ? 185.933 117.990 111.281 1.00 64.66  ? 37  ASN D CA  1 
ATOM   11225 C  C   . ASN D 3 141 ? 187.427 118.155 111.507 1.00 64.66  ? 37  ASN D C   1 
ATOM   11226 O  O   . ASN D 3 141 ? 187.952 119.270 111.415 1.00 64.66  ? 37  ASN D O   1 
ATOM   11227 C  CB  . ASN D 3 141 ? 185.620 117.890 109.785 1.00 64.66  ? 37  ASN D CB  1 
ATOM   11228 C  CG  . ASN D 3 141 ? 186.099 116.587 109.174 1.00 64.66  ? 37  ASN D CG  1 
ATOM   11229 O  OD1 . ASN D 3 141 ? 186.690 115.748 109.854 1.00 64.66  ? 37  ASN D OD1 1 
ATOM   11230 N  ND2 . ASN D 3 141 ? 185.841 116.411 107.884 1.00 64.66  ? 37  ASN D ND2 1 
ATOM   11231 N  N   . GLN D 3 142 ? 188.106 117.049 111.806 1.00 81.80  ? 38  GLN D N   1 
ATOM   11232 C  CA  . GLN D 3 142 ? 189.548 117.063 112.009 1.00 81.80  ? 38  GLN D CA  1 
ATOM   11233 C  C   . GLN D 3 142 ? 190.330 116.914 110.712 1.00 81.80  ? 38  GLN D C   1 
ATOM   11234 O  O   . GLN D 3 142 ? 191.472 117.381 110.640 1.00 81.80  ? 38  GLN D O   1 
ATOM   11235 C  CB  . GLN D 3 142 ? 189.954 115.947 112.973 1.00 81.80  ? 38  GLN D CB  1 
ATOM   11236 C  CG  . GLN D 3 142 ? 189.441 116.124 114.391 1.00 81.80  ? 38  GLN D CG  1 
ATOM   11237 C  CD  . GLN D 3 142 ? 189.845 114.979 115.298 1.00 81.80  ? 38  GLN D CD  1 
ATOM   11238 O  OE1 . GLN D 3 142 ? 190.459 114.008 114.854 1.00 81.80  ? 38  GLN D OE1 1 
ATOM   11239 N  NE2 . GLN D 3 142 ? 189.502 115.086 116.576 1.00 81.80  ? 38  GLN D NE2 1 
ATOM   11240 N  N   . ASN D 3 143 ? 189.749 116.281 109.696 1.00 80.74  ? 39  ASN D N   1 
ATOM   11241 C  CA  . ASN D 3 143 ? 190.429 116.025 108.435 1.00 80.74  ? 39  ASN D CA  1 
ATOM   11242 C  C   . ASN D 3 143 ? 190.699 117.290 107.632 1.00 80.74  ? 39  ASN D C   1 
ATOM   11243 O  O   . ASN D 3 143 ? 191.859 117.566 107.310 1.00 80.74  ? 39  ASN D O   1 
ATOM   11244 C  CB  . ASN D 3 143 ? 189.606 115.050 107.585 1.00 80.74  ? 39  ASN D CB  1 
ATOM   11245 C  CG  . ASN D 3 143 ? 189.564 113.655 108.175 1.00 80.74  ? 39  ASN D CG  1 
ATOM   11246 O  OD1 . ASN D 3 143 ? 190.571 113.144 108.667 1.00 80.74  ? 39  ASN D OD1 1 
ATOM   11247 N  ND2 . ASN D 3 143 ? 188.394 113.028 108.127 1.00 80.74  ? 39  ASN D ND2 1 
ATOM   11248 N  N   . LEU D 3 144 ? 189.666 118.061 107.306 1.00 76.94  ? 40  LEU D N   1 
ATOM   11249 C  CA  . LEU D 3 144 ? 189.795 119.233 106.452 1.00 76.94  ? 40  LEU D CA  1 
ATOM   11250 C  C   . LEU D 3 144 ? 190.454 120.369 107.223 1.00 76.94  ? 40  LEU D C   1 
ATOM   11251 O  O   . LEU D 3 144 ? 189.925 120.823 108.243 1.00 76.94  ? 40  LEU D O   1 
ATOM   11252 C  CB  . LEU D 3 144 ? 188.431 119.682 105.926 1.00 76.94  ? 40  LEU D CB  1 
ATOM   11253 C  CG  . LEU D 3 144 ? 187.874 118.999 104.671 1.00 76.94  ? 40  LEU D CG  1 
ATOM   11254 C  CD1 . LEU D 3 144 ? 188.793 119.230 103.478 1.00 76.94  ? 40  LEU D CD1 1 
ATOM   11255 C  CD2 . LEU D 3 144 ? 187.627 117.511 104.891 1.00 76.94  ? 40  LEU D CD2 1 
ATOM   11256 N  N   . SER D 3 145 ? 191.606 120.821 106.733 1.00 83.62  ? 41  SER D N   1 
ATOM   11257 C  CA  . SER D 3 145 ? 192.262 121.979 107.322 1.00 83.62  ? 41  SER D CA  1 
ATOM   11258 C  C   . SER D 3 145 ? 191.458 123.238 107.029 1.00 83.62  ? 41  SER D C   1 
ATOM   11259 O  O   . SER D 3 145 ? 190.946 123.423 105.922 1.00 83.62  ? 41  SER D O   1 
ATOM   11260 C  CB  . SER D 3 145 ? 193.684 122.119 106.780 1.00 83.62  ? 41  SER D CB  1 
ATOM   11261 O  OG  . SER D 3 145 ? 193.675 122.411 105.393 1.00 83.62  ? 41  SER D OG  1 
ATOM   11262 N  N   . GLU D 3 146 ? 191.354 124.115 108.031 1.00 82.24  ? 42  GLU D N   1 
ATOM   11263 C  CA  . GLU D 3 146 ? 190.493 125.285 107.893 1.00 82.24  ? 42  GLU D CA  1 
ATOM   11264 C  C   . GLU D 3 146 ? 191.092 126.330 106.961 1.00 82.24  ? 42  GLU D C   1 
ATOM   11265 O  O   . GLU D 3 146 ? 190.483 127.382 106.739 1.00 82.24  ? 42  GLU D O   1 
ATOM   11266 C  CB  . GLU D 3 146 ? 190.201 125.892 109.266 1.00 82.24  ? 42  GLU D CB  1 
ATOM   11267 C  CG  . GLU D 3 146 ? 189.326 125.010 110.144 1.00 82.24  ? 42  GLU D CG  1 
ATOM   11268 C  CD  . GLU D 3 146 ? 189.016 125.640 111.486 1.00 82.24  ? 42  GLU D CD  1 
ATOM   11269 O  OE1 . GLU D 3 146 ? 189.576 126.716 111.782 1.00 82.24  ? 42  GLU D OE1 1 
ATOM   11270 O  OE2 . GLU D 3 146 ? 188.211 125.059 112.244 1.00 82.24  ? 42  GLU D OE2 1 
ATOM   11271 N  N   . ALA D 3 147 ? 192.280 126.069 106.410 1.00 81.57  ? 43  ALA D N   1 
ATOM   11272 C  CA  . ALA D 3 147 ? 192.794 126.926 105.348 1.00 81.57  ? 43  ALA D CA  1 
ATOM   11273 C  C   . ALA D 3 147 ? 192.018 126.706 104.055 1.00 81.57  ? 43  ALA D C   1 
ATOM   11274 O  O   . ALA D 3 147 ? 191.665 127.667 103.360 1.00 81.57  ? 43  ALA D O   1 
ATOM   11275 C  CB  . ALA D 3 147 ? 194.285 126.666 105.135 1.00 81.57  ? 43  ALA D CB  1 
ATOM   11276 N  N   . LYS D 3 148 ? 191.734 125.444 103.724 1.00 79.45  ? 44  LYS D N   1 
ATOM   11277 C  CA  . LYS D 3 148 ? 190.893 125.154 102.568 1.00 79.45  ? 44  LYS D CA  1 
ATOM   11278 C  C   . LYS D 3 148 ? 189.447 125.553 102.830 1.00 79.45  ? 44  LYS D C   1 
ATOM   11279 O  O   . LYS D 3 148 ? 188.655 125.698 101.891 1.00 79.45  ? 44  LYS D O   1 
ATOM   11280 C  CB  . LYS D 3 148 ? 190.987 123.672 102.206 1.00 79.45  ? 44  LYS D CB  1 
ATOM   11281 C  CG  . LYS D 3 148 ? 192.342 123.250 101.666 1.00 79.45  ? 44  LYS D CG  1 
ATOM   11282 C  CD  . LYS D 3 148 ? 192.358 121.775 101.298 1.00 79.45  ? 44  LYS D CD  1 
ATOM   11283 C  CE  . LYS D 3 148 ? 193.722 121.353 100.776 1.00 79.45  ? 44  LYS D CE  1 
ATOM   11284 N  NZ  . LYS D 3 148 ? 193.764 119.907 100.424 1.00 79.45  ? 44  LYS D NZ  1 
ATOM   11285 N  N   . LEU D 3 149 ? 189.080 125.727 104.102 1.00 75.30  ? 45  LEU D N   1 
ATOM   11286 C  CA  . LEU D 3 149 ? 187.760 126.264 104.415 1.00 75.30  ? 45  LEU D CA  1 
ATOM   11287 C  C   . LEU D 3 149 ? 187.734 127.778 104.256 1.00 75.30  ? 45  LEU D C   1 
ATOM   11288 O  O   . LEU D 3 149 ? 186.733 128.343 103.800 1.00 75.30  ? 45  LEU D O   1 
ATOM   11289 C  CB  . LEU D 3 149 ? 187.336 125.863 105.828 1.00 75.30  ? 45  LEU D CB  1 
ATOM   11290 C  CG  . LEU D 3 149 ? 186.699 124.481 106.012 1.00 75.30  ? 45  LEU D CG  1 
ATOM   11291 C  CD1 . LEU D 3 149 ? 187.721 123.365 105.884 1.00 75.30  ? 45  LEU D CD1 1 
ATOM   11292 C  CD2 . LEU D 3 149 ? 185.976 124.399 107.348 1.00 75.30  ? 45  LEU D CD2 1 
ATOM   11293 N  N   . ASP D 3 150 ? 188.822 128.457 104.627 1.00 78.94  ? 46  ASP D N   1 
ATOM   11294 C  CA  . ASP D 3 150 ? 188.904 129.891 104.373 1.00 78.94  ? 46  ASP D CA  1 
ATOM   11295 C  C   . ASP D 3 150 ? 188.908 130.176 102.878 1.00 78.94  ? 46  ASP D C   1 
ATOM   11296 O  O   . ASP D 3 150 ? 188.233 131.101 102.410 1.00 78.94  ? 46  ASP D O   1 
ATOM   11297 C  CB  . ASP D 3 150 ? 190.149 130.478 105.038 1.00 78.94  ? 46  ASP D CB  1 
ATOM   11298 C  CG  . ASP D 3 150 ? 190.050 130.493 106.549 1.00 78.94  ? 46  ASP D CG  1 
ATOM   11299 O  OD1 . ASP D 3 150 ? 188.918 130.579 107.070 1.00 78.94  ? 46  ASP D OD1 1 
ATOM   11300 O  OD2 . ASP D 3 150 ? 191.104 130.422 107.216 1.00 78.94  ? 46  ASP D OD2 1 
ATOM   11301 N  N   . GLU D 3 151 ? 189.662 129.385 102.111 1.00 81.50  ? 47  GLU D N   1 
ATOM   11302 C  CA  . GLU D 3 151 ? 189.620 129.505 100.657 1.00 81.50  ? 47  GLU D CA  1 
ATOM   11303 C  C   . GLU D 3 151 ? 188.238 129.157 100.118 1.00 81.50  ? 47  GLU D C   1 
ATOM   11304 O  O   . GLU D 3 151 ? 187.730 129.830 99.214  1.00 81.50  ? 47  GLU D O   1 
ATOM   11305 C  CB  . GLU D 3 151 ? 190.684 128.604 100.032 1.00 81.50  ? 47  GLU D CB  1 
ATOM   11306 C  CG  . GLU D 3 151 ? 190.775 128.694 98.520  1.00 81.50  ? 47  GLU D CG  1 
ATOM   11307 C  CD  . GLU D 3 151 ? 191.860 127.799 97.953  1.00 81.50  ? 47  GLU D CD  1 
ATOM   11308 O  OE1 . GLU D 3 151 ? 192.528 127.100 98.743  1.00 81.50  ? 47  GLU D OE1 1 
ATOM   11309 O  OE2 . GLU D 3 151 ? 192.042 127.792 96.717  1.00 81.50  ? 47  GLU D OE2 1 
ATOM   11310 N  N   . TYR D 3 152 ? 187.617 128.110 100.666 1.00 72.34  ? 48  TYR D N   1 
ATOM   11311 C  CA  . TYR D 3 152 ? 186.290 127.696 100.221 1.00 72.34  ? 48  TYR D CA  1 
ATOM   11312 C  C   . TYR D 3 152 ? 185.260 128.803 100.415 1.00 72.34  ? 48  TYR D C   1 
ATOM   11313 O  O   . TYR D 3 152 ? 184.433 129.053 99.529  1.00 72.34  ? 48  TYR D O   1 
ATOM   11314 C  CB  . TYR D 3 152 ? 185.874 126.433 100.972 1.00 72.34  ? 48  TYR D CB  1 
ATOM   11315 C  CG  . TYR D 3 152 ? 184.460 125.979 100.703 1.00 72.34  ? 48  TYR D CG  1 
ATOM   11316 C  CD1 . TYR D 3 152 ? 184.120 125.357 99.511  1.00 72.34  ? 48  TYR D CD1 1 
ATOM   11317 C  CD2 . TYR D 3 152 ? 183.465 126.168 101.650 1.00 72.34  ? 48  TYR D CD2 1 
ATOM   11318 C  CE1 . TYR D 3 152 ? 182.825 124.940 99.270  1.00 72.34  ? 48  TYR D CE1 1 
ATOM   11319 C  CE2 . TYR D 3 152 ? 182.172 125.756 101.420 1.00 72.34  ? 48  TYR D CE2 1 
ATOM   11320 C  CZ  . TYR D 3 152 ? 181.855 125.143 100.230 1.00 72.34  ? 48  TYR D CZ  1 
ATOM   11321 O  OH  . TYR D 3 152 ? 180.563 124.731 99.999  1.00 72.34  ? 48  TYR D OH  1 
ATOM   11322 N  N   . ILE D 3 153 ? 185.296 129.476 101.565 1.00 73.95  ? 49  ILE D N   1 
ATOM   11323 C  CA  . ILE D 3 153 ? 184.312 130.515 101.854 1.00 73.95  ? 49  ILE D CA  1 
ATOM   11324 C  C   . ILE D 3 153 ? 184.640 131.786 101.083 1.00 73.95  ? 49  ILE D C   1 
ATOM   11325 O  O   . ILE D 3 153 ? 183.741 132.497 100.616 1.00 73.95  ? 49  ILE D O   1 
ATOM   11326 C  CB  . ILE D 3 153 ? 184.245 130.765 103.370 1.00 73.95  ? 49  ILE D CB  1 
ATOM   11327 C  CG1 . ILE D 3 153 ? 183.841 129.481 104.091 1.00 73.95  ? 49  ILE D CG1 1 
ATOM   11328 C  CG2 . ILE D 3 153 ? 183.254 131.868 103.690 1.00 73.95  ? 49  ILE D CG2 1 
ATOM   11329 C  CD1 . ILE D 3 153 ? 184.108 129.524 105.563 1.00 73.95  ? 49  ILE D CD1 1 
ATOM   11330 N  N   . ALA D 3 154 ? 185.932 132.093 100.935 1.00 81.38  ? 50  ALA D N   1 
ATOM   11331 C  CA  . ALA D 3 154 ? 186.326 133.244 100.128 1.00 81.38  ? 50  ALA D CA  1 
ATOM   11332 C  C   . ALA D 3 154 ? 185.860 133.085 98.688  1.00 81.38  ? 50  ALA D C   1 
ATOM   11333 O  O   . ALA D 3 154 ? 185.413 134.052 98.060  1.00 81.38  ? 50  ALA D O   1 
ATOM   11334 C  CB  . ALA D 3 154 ? 187.841 133.435 100.185 1.00 81.38  ? 50  ALA D CB  1 
ATOM   11335 N  N   . ILE D 3 155 ? 185.951 131.867 98.149  1.00 86.65  ? 51  ILE D N   1 
ATOM   11336 C  CA  . ILE D 3 155 ? 185.430 131.606 96.811  1.00 86.65  ? 51  ILE D CA  1 
ATOM   11337 C  C   . ILE D 3 155 ? 183.907 131.643 96.819  1.00 86.65  ? 51  ILE D C   1 
ATOM   11338 O  O   . ILE D 3 155 ? 183.276 132.098 95.857  1.00 86.65  ? 51  ILE D O   1 
ATOM   11339 C  CB  . ILE D 3 155 ? 185.967 130.262 96.284  1.00 86.65  ? 51  ILE D CB  1 
ATOM   11340 C  CG1 . ILE D 3 155 ? 187.486 130.327 96.113  1.00 86.65  ? 51  ILE D CG1 1 
ATOM   11341 C  CG2 . ILE D 3 155 ? 185.302 129.890 94.969  1.00 86.65  ? 51  ILE D CG2 1 
ATOM   11342 C  CD1 . ILE D 3 155 ? 188.130 128.982 95.857  1.00 86.65  ? 51  ILE D CD1 1 
ATOM   11343 N  N   . ALA D 3 156 ? 183.292 131.182 97.911  1.00 82.78  ? 52  ALA D N   1 
ATOM   11344 C  CA  . ALA D 3 156 ? 181.834 131.167 97.986  1.00 82.78  ? 52  ALA D CA  1 
ATOM   11345 C  C   . ALA D 3 156 ? 181.266 132.578 98.068  1.00 82.78  ? 52  ALA D C   1 
ATOM   11346 O  O   . ALA D 3 156 ? 180.085 132.797 97.775  1.00 82.78  ? 52  ALA D O   1 
ATOM   11347 C  CB  . ALA D 3 156 ? 181.377 130.333 99.182  1.00 82.78  ? 52  ALA D CB  1 
ATOM   11348 N  N   . LYS D 3 157 ? 182.088 133.551 98.468  1.00 89.60  ? 53  LYS D N   1 
ATOM   11349 C  CA  . LYS D 3 157 ? 181.626 134.935 98.513  1.00 89.60  ? 53  LYS D CA  1 
ATOM   11350 C  C   . LYS D 3 157 ? 182.019 135.690 97.249  1.00 89.60  ? 53  LYS D C   1 
ATOM   11351 O  O   . LYS D 3 157 ? 181.223 136.462 96.702  1.00 89.60  ? 53  LYS D O   1 
ATOM   11352 C  CB  . LYS D 3 157 ? 182.183 135.643 99.747  1.00 89.60  ? 53  LYS D CB  1 
ATOM   11353 C  CG  . LYS D 3 157 ? 181.581 135.195 101.063 1.00 89.60  ? 53  LYS D CG  1 
ATOM   11354 C  CD  . LYS D 3 157 ? 182.151 136.010 102.210 1.00 89.60  ? 53  LYS D CD  1 
ATOM   11355 C  CE  . LYS D 3 157 ? 181.556 135.591 103.540 1.00 89.60  ? 53  LYS D CE  1 
ATOM   11356 N  NZ  . LYS D 3 157 ? 182.121 136.384 104.670 1.00 89.60  ? 53  LYS D NZ  1 
ATOM   11357 N  N   . GLU D 3 158 ? 183.247 135.485 96.774  1.00 98.25  ? 54  GLU D N   1 
ATOM   11358 C  CA  . GLU D 3 158 ? 183.740 136.242 95.628  1.00 98.25  ? 54  GLU D CA  1 
ATOM   11359 C  C   . GLU D 3 158 ? 183.171 135.711 94.317  1.00 98.25  ? 54  GLU D C   1 
ATOM   11360 O  O   . GLU D 3 158 ? 182.644 136.479 93.505  1.00 98.25  ? 54  GLU D O   1 
ATOM   11361 C  CB  . GLU D 3 158 ? 185.269 136.208 95.602  1.00 98.25  ? 54  GLU D CB  1 
ATOM   11362 C  CG  . GLU D 3 158 ? 185.925 136.951 96.755  1.00 98.25  ? 54  GLU D CG  1 
ATOM   11363 C  CD  . GLU D 3 158 ? 187.437 136.850 96.727  1.00 98.25  ? 54  GLU D CD  1 
ATOM   11364 O  OE1 . GLU D 3 158 ? 187.969 136.097 95.884  1.00 98.25  ? 54  GLU D OE1 1 
ATOM   11365 O  OE2 . GLU D 3 158 ? 188.095 137.523 97.549  1.00 98.25  ? 54  GLU D OE2 1 
ATOM   11366 N  N   . LYS D 3 159 ? 183.267 134.399 94.095  1.00 98.22  ? 55  LYS D N   1 
ATOM   11367 C  CA  . LYS D 3 159 ? 182.838 133.828 92.824  1.00 98.22  ? 55  LYS D CA  1 
ATOM   11368 C  C   . LYS D 3 159 ? 181.362 133.451 92.826  1.00 98.22  ? 55  LYS D C   1 
ATOM   11369 O  O   . LYS D 3 159 ? 180.816 133.106 91.772  1.00 98.22  ? 55  LYS D O   1 
ATOM   11370 C  CB  . LYS D 3 159 ? 183.691 132.604 92.487  1.00 98.22  ? 55  LYS D CB  1 
ATOM   11371 C  CG  . LYS D 3 159 ? 185.146 132.931 92.192  1.00 98.22  ? 55  LYS D CG  1 
ATOM   11372 C  CD  . LYS D 3 159 ? 185.935 131.681 91.844  1.00 98.22  ? 55  LYS D CD  1 
ATOM   11373 C  CE  . LYS D 3 159 ? 187.396 132.004 91.583  1.00 98.22  ? 55  LYS D CE  1 
ATOM   11374 N  NZ  . LYS D 3 159 ? 188.182 130.780 91.265  1.00 98.22  ? 55  LYS D NZ  1 
ATOM   11375 N  N   . HIS D 3 160 ? 180.702 133.508 93.982  1.00 94.38  ? 56  HIS D N   1 
ATOM   11376 C  CA  . HIS D 3 160 ? 179.294 133.155 94.081  1.00 94.38  ? 56  HIS D CA  1 
ATOM   11377 C  C   . HIS D 3 160 ? 178.512 134.007 95.068  1.00 94.38  ? 56  HIS D C   1 
ATOM   11378 O  O   . HIS D 3 160 ? 179.130 134.757 95.832  1.00 94.38  ? 56  HIS D O   1 
ATOM   11379 C  CB  . HIS D 3 160 ? 179.141 131.674 94.465  1.00 94.38  ? 56  HIS D CB  1 
ATOM   11380 C  CG  . HIS D 3 160 ? 179.611 130.726 93.407  1.00 94.38  ? 56  HIS D CG  1 
ATOM   11381 N  ND1 . HIS D 3 160 ? 180.918 130.297 93.317  1.00 94.38  ? 56  HIS D ND1 1 
ATOM   11382 C  CD2 . HIS D 3 160 ? 178.947 130.124 92.391  1.00 94.38  ? 56  HIS D CD2 1 
ATOM   11383 C  CE1 . HIS D 3 160 ? 181.039 129.473 92.292  1.00 94.38  ? 56  HIS D CE1 1 
ATOM   11384 N  NE2 . HIS D 3 160 ? 179.858 129.350 91.714  1.00 94.38  ? 56  HIS D NE2 1 
ATOM   11385 N  N   . GLY D 3 161 ? 177.184 133.919 95.078  1.00 90.69  ? 57  GLY D N   1 
ATOM   11386 C  CA  . GLY D 3 161 ? 176.375 134.750 95.945  1.00 90.69  ? 57  GLY D CA  1 
ATOM   11387 C  C   . GLY D 3 161 ? 176.212 134.252 97.362  1.00 90.69  ? 57  GLY D C   1 
ATOM   11388 O  O   . GLY D 3 161 ? 175.467 134.867 98.133  1.00 90.69  ? 57  GLY D O   1 
ATOM   11389 N  N   . TYR D 3 162 ? 176.878 133.163 97.735  1.00 82.98  ? 58  TYR D N   1 
ATOM   11390 C  CA  . TYR D 3 162 ? 176.752 132.646 99.089  1.00 82.98  ? 58  TYR D CA  1 
ATOM   11391 C  C   . TYR D 3 162 ? 177.519 133.521 100.074 1.00 82.98  ? 58  TYR D C   1 
ATOM   11392 O  O   . TYR D 3 162 ? 178.324 134.373 99.690  1.00 82.98  ? 58  TYR D O   1 
ATOM   11393 C  CB  . TYR D 3 162 ? 177.243 131.201 99.157  1.00 82.98  ? 58  TYR D CB  1 
ATOM   11394 C  CG  . TYR D 3 162 ? 176.315 130.224 98.473  1.00 82.98  ? 58  TYR D CG  1 
ATOM   11395 C  CD1 . TYR D 3 162 ? 175.015 130.587 98.146  1.00 82.98  ? 58  TYR D CD1 1 
ATOM   11396 C  CD2 . TYR D 3 162 ? 176.736 128.941 98.156  1.00 82.98  ? 58  TYR D CD2 1 
ATOM   11397 C  CE1 . TYR D 3 162 ? 174.160 129.700 97.523  1.00 82.98  ? 58  TYR D CE1 1 
ATOM   11398 C  CE2 . TYR D 3 162 ? 175.887 128.046 97.532  1.00 82.98  ? 58  TYR D CE2 1 
ATOM   11399 C  CZ  . TYR D 3 162 ? 174.603 128.431 97.218  1.00 82.98  ? 58  TYR D CZ  1 
ATOM   11400 O  OH  . TYR D 3 162 ? 173.758 127.542 96.596  1.00 82.98  ? 58  TYR D OH  1 
ATOM   11401 N  N   . ASN D 3 163 ? 177.261 133.299 101.361 1.00 77.36  ? 59  ASN D N   1 
ATOM   11402 C  CA  . ASN D 3 163 ? 177.779 134.173 102.401 1.00 77.36  ? 59  ASN D CA  1 
ATOM   11403 C  C   . ASN D 3 163 ? 178.752 133.425 103.313 1.00 77.36  ? 59  ASN D C   1 
ATOM   11404 O  O   . ASN D 3 163 ? 179.542 132.583 102.878 1.00 77.36  ? 59  ASN D O   1 
ATOM   11405 C  CB  . ASN D 3 163 ? 176.621 134.784 103.189 1.00 77.36  ? 59  ASN D CB  1 
ATOM   11406 C  CG  . ASN D 3 163 ? 175.719 133.735 103.819 1.00 77.36  ? 59  ASN D CG  1 
ATOM   11407 O  OD1 . ASN D 3 163 ? 176.006 132.538 103.774 1.00 77.36  ? 59  ASN D OD1 1 
ATOM   11408 N  ND2 . ASN D 3 163 ? 174.615 134.184 104.404 1.00 77.36  ? 59  ASN D ND2 1 
ATOM   11409 N  N   . MET D 3 164 ? 178.689 133.745 104.607 1.00 79.59  ? 60  MET D N   1 
ATOM   11410 C  CA  . MET D 3 164 ? 179.632 133.184 105.569 1.00 79.59  ? 60  MET D CA  1 
ATOM   11411 C  C   . MET D 3 164 ? 179.040 131.960 106.266 1.00 79.59  ? 60  MET D C   1 
ATOM   11412 O  O   . MET D 3 164 ? 179.623 131.435 107.222 1.00 79.59  ? 60  MET D O   1 
ATOM   11413 C  CB  . MET D 3 164 ? 180.012 134.267 106.583 1.00 79.59  ? 60  MET D CB  1 
ATOM   11414 C  CG  . MET D 3 164 ? 181.256 134.013 107.433 1.00 79.59  ? 60  MET D CG  1 
ATOM   11415 S  SD  . MET D 3 164 ? 182.802 134.129 106.519 1.00 79.59  ? 60  MET D SD  1 
ATOM   11416 C  CE  . MET D 3 164 ? 183.910 133.228 107.592 1.00 79.59  ? 60  MET D CE  1 
ATOM   11417 N  N   . GLU D 3 165 ? 177.885 131.484 105.793 1.00 66.46  ? 61  GLU D N   1 
ATOM   11418 C  CA  . GLU D 3 165 ? 177.173 130.423 106.501 1.00 66.46  ? 61  GLU D CA  1 
ATOM   11419 C  C   . GLU D 3 165 ? 176.644 129.365 105.539 1.00 66.46  ? 61  GLU D C   1 
ATOM   11420 O  O   . GLU D 3 165 ? 176.853 128.162 105.749 1.00 66.46  ? 61  GLU D O   1 
ATOM   11421 C  CB  . GLU D 3 165 ? 176.027 131.025 107.311 1.00 66.46  ? 61  GLU D CB  1 
ATOM   11422 C  CG  . GLU D 3 165 ? 175.214 130.020 108.109 1.00 66.46  ? 61  GLU D CG  1 
ATOM   11423 C  CD  . GLU D 3 165 ? 174.092 130.680 108.889 1.00 66.46  ? 61  GLU D CD  1 
ATOM   11424 O  OE1 . GLU D 3 165 ? 173.940 131.916 108.781 1.00 66.46  ? 61  GLU D OE1 1 
ATOM   11425 O  OE2 . GLU D 3 165 ? 173.363 129.966 109.608 1.00 66.46  ? 61  GLU D OE2 1 
ATOM   11426 N  N   . GLN D 3 166 ? 175.944 129.793 104.485 1.00 63.89  ? 62  GLN D N   1 
ATOM   11427 C  CA  . GLN D 3 166 ? 175.376 128.843 103.534 1.00 63.89  ? 62  GLN D CA  1 
ATOM   11428 C  C   . GLN D 3 166 ? 176.465 128.037 102.841 1.00 63.89  ? 62  GLN D C   1 
ATOM   11429 O  O   . GLN D 3 166 ? 176.209 126.931 102.350 1.00 63.89  ? 62  GLN D O   1 
ATOM   11430 C  CB  . GLN D 3 166 ? 174.511 129.579 102.514 1.00 63.89  ? 62  GLN D CB  1 
ATOM   11431 C  CG  . GLN D 3 166 ? 173.260 130.189 103.116 1.00 63.89  ? 62  GLN D CG  1 
ATOM   11432 C  CD  . GLN D 3 166 ? 172.421 130.932 102.098 1.00 63.89  ? 62  GLN D CD  1 
ATOM   11433 O  OE1 . GLN D 3 166 ? 172.801 131.054 100.934 1.00 63.89  ? 62  GLN D OE1 1 
ATOM   11434 N  NE2 . GLN D 3 166 ? 171.272 131.435 102.533 1.00 63.89  ? 62  GLN D NE2 1 
ATOM   11435 N  N   . ALA D 3 167 ? 177.685 128.573 102.791 1.00 54.78  ? 63  ALA D N   1 
ATOM   11436 C  CA  . ALA D 3 167 ? 178.814 127.779 102.325 1.00 54.78  ? 63  ALA D CA  1 
ATOM   11437 C  C   . ALA D 3 167 ? 179.111 126.641 103.291 1.00 54.78  ? 63  ALA D C   1 
ATOM   11438 O  O   . ALA D 3 167 ? 179.506 125.547 102.874 1.00 54.78  ? 63  ALA D O   1 
ATOM   11439 C  CB  . ALA D 3 167 ? 180.044 128.667 102.145 1.00 54.78  ? 63  ALA D CB  1 
ATOM   11440 N  N   . LEU D 3 168 ? 178.915 126.877 104.590 1.00 45.81  ? 64  LEU D N   1 
ATOM   11441 C  CA  . LEU D 3 168 ? 179.165 125.832 105.576 1.00 45.81  ? 64  LEU D CA  1 
ATOM   11442 C  C   . LEU D 3 168 ? 178.060 124.787 105.556 1.00 45.81  ? 64  LEU D C   1 
ATOM   11443 O  O   . LEU D 3 168 ? 178.337 123.582 105.574 1.00 45.81  ? 64  LEU D O   1 
ATOM   11444 C  CB  . LEU D 3 168 ? 179.297 126.437 106.972 1.00 45.81  ? 64  LEU D CB  1 
ATOM   11445 C  CG  . LEU D 3 168 ? 180.644 127.040 107.380 1.00 45.81  ? 64  LEU D CG  1 
ATOM   11446 C  CD1 . LEU D 3 168 ? 181.752 126.003 107.333 1.00 45.81  ? 64  LEU D CD1 1 
ATOM   11447 C  CD2 . LEU D 3 168 ? 180.994 128.264 106.552 1.00 45.81  ? 64  LEU D CD2 1 
ATOM   11448 N  N   . GLY D 3 169 ? 176.800 125.228 105.520 1.00 48.37  ? 65  GLY D N   1 
ATOM   11449 C  CA  . GLY D 3 169 ? 175.705 124.277 105.424 1.00 48.37  ? 65  GLY D CA  1 
ATOM   11450 C  C   . GLY D 3 169 ? 175.760 123.455 104.150 1.00 48.37  ? 65  GLY D C   1 
ATOM   11451 O  O   . GLY D 3 169 ? 175.573 122.234 104.175 1.00 48.37  ? 65  GLY D O   1 
ATOM   11452 N  N   . MET D 3 170 ? 176.032 124.111 103.020 1.00 56.27  ? 66  MET D N   1 
ATOM   11453 C  CA  . MET D 3 170 ? 176.137 123.394 101.755 1.00 56.27  ? 66  MET D CA  1 
ATOM   11454 C  C   . MET D 3 170 ? 177.376 122.507 101.733 1.00 56.27  ? 66  MET D C   1 
ATOM   11455 O  O   . MET D 3 170 ? 177.401 121.477 101.049 1.00 56.27  ? 66  MET D O   1 
ATOM   11456 C  CB  . MET D 3 170 ? 176.165 124.390 100.596 1.00 56.27  ? 66  MET D CB  1 
ATOM   11457 C  CG  . MET D 3 170 ? 175.913 123.777 99.232  1.00 56.27  ? 66  MET D CG  1 
ATOM   11458 S  SD  . MET D 3 170 ? 174.204 123.224 99.081  1.00 56.27  ? 66  MET D SD  1 
ATOM   11459 C  CE  . MET D 3 170 ? 174.345 122.014 97.774  1.00 56.27  ? 66  MET D CE  1 
ATOM   11460 N  N   . LEU D 3 171 ? 178.417 122.893 102.476 1.00 47.65  ? 67  LEU D N   1 
ATOM   11461 C  CA  . LEU D 3 171 ? 179.603 122.050 102.582 1.00 47.65  ? 67  LEU D CA  1 
ATOM   11462 C  C   . LEU D 3 171 ? 179.311 120.798 103.396 1.00 47.65  ? 67  LEU D C   1 
ATOM   11463 O  O   . LEU D 3 171 ? 179.837 119.718 103.101 1.00 47.65  ? 67  LEU D O   1 
ATOM   11464 C  CB  . LEU D 3 171 ? 180.757 122.839 103.201 1.00 47.65  ? 67  LEU D CB  1 
ATOM   11465 C  CG  . LEU D 3 171 ? 182.092 122.104 103.341 1.00 47.65  ? 67  LEU D CG  1 
ATOM   11466 C  CD1 . LEU D 3 171 ? 182.629 121.701 101.981 1.00 47.65  ? 67  LEU D CD1 1 
ATOM   11467 C  CD2 . LEU D 3 171 ? 183.099 122.968 104.079 1.00 47.65  ? 67  LEU D CD2 1 
ATOM   11468 N  N   . PHE D 3 172 ? 178.472 120.920 104.428 1.00 40.69  ? 68  PHE D N   1 
ATOM   11469 C  CA  . PHE D 3 172 ? 178.078 119.739 105.186 1.00 40.69  ? 68  PHE D CA  1 
ATOM   11470 C  C   . PHE D 3 172 ? 177.060 118.901 104.423 1.00 40.69  ? 68  PHE D C   1 
ATOM   11471 O  O   . PHE D 3 172 ? 176.915 117.705 104.698 1.00 40.69  ? 68  PHE D O   1 
ATOM   11472 C  CB  . PHE D 3 172 ? 177.520 120.140 106.551 1.00 40.69  ? 68  PHE D CB  1 
ATOM   11473 C  CG  . PHE D 3 172 ? 177.118 118.971 107.406 1.00 40.69  ? 68  PHE D CG  1 
ATOM   11474 C  CD1 . PHE D 3 172 ? 178.075 118.199 108.044 1.00 40.69  ? 68  PHE D CD1 1 
ATOM   11475 C  CD2 . PHE D 3 172 ? 175.784 118.635 107.559 1.00 40.69  ? 68  PHE D CD2 1 
ATOM   11476 C  CE1 . PHE D 3 172 ? 177.708 117.120 108.825 1.00 40.69  ? 68  PHE D CE1 1 
ATOM   11477 C  CE2 . PHE D 3 172 ? 175.412 117.556 108.338 1.00 40.69  ? 68  PHE D CE2 1 
ATOM   11478 C  CZ  . PHE D 3 172 ? 176.375 116.798 108.970 1.00 40.69  ? 68  PHE D CZ  1 
ATOM   11479 N  N   . TRP D 3 173 ? 176.357 119.503 103.459 1.00 54.75  ? 69  TRP D N   1 
ATOM   11480 C  CA  . TRP D 3 173 ? 175.369 118.751 102.692 1.00 54.75  ? 69  TRP D CA  1 
ATOM   11481 C  C   . TRP D 3 173 ? 176.013 117.634 101.878 1.00 54.75  ? 69  TRP D C   1 
ATOM   11482 O  O   . TRP D 3 173 ? 175.332 116.676 101.497 1.00 54.75  ? 69  TRP D O   1 
ATOM   11483 C  CB  . TRP D 3 173 ? 174.586 119.695 101.778 1.00 54.75  ? 69  TRP D CB  1 
ATOM   11484 C  CG  . TRP D 3 173 ? 173.496 119.022 100.996 1.00 54.75  ? 69  TRP D CG  1 
ATOM   11485 C  CD1 . TRP D 3 173 ? 173.521 118.692 99.672  1.00 54.75  ? 69  TRP D CD1 1 
ATOM   11486 C  CD2 . TRP D 3 173 ? 172.222 118.591 101.491 1.00 54.75  ? 69  TRP D CD2 1 
ATOM   11487 N  NE1 . TRP D 3 173 ? 172.341 118.086 99.312  1.00 54.75  ? 69  TRP D NE1 1 
ATOM   11488 C  CE2 . TRP D 3 173 ? 171.527 118.012 100.411 1.00 54.75  ? 69  TRP D CE2 1 
ATOM   11489 C  CE3 . TRP D 3 173 ? 171.601 118.641 102.743 1.00 54.75  ? 69  TRP D CE3 1 
ATOM   11490 C  CZ2 . TRP D 3 173 ? 170.244 117.486 100.544 1.00 54.75  ? 69  TRP D CZ2 1 
ATOM   11491 C  CZ3 . TRP D 3 173 ? 170.326 118.118 102.874 1.00 54.75  ? 69  TRP D CZ3 1 
ATOM   11492 C  CH2 . TRP D 3 173 ? 169.662 117.548 101.781 1.00 54.75  ? 69  TRP D CH2 1 
ATOM   11493 N  N   . HIS D 3 174 ? 177.315 117.730 101.609 1.00 60.00  ? 70  HIS D N   1 
ATOM   11494 C  CA  . HIS D 3 174 ? 178.026 116.722 100.834 1.00 60.00  ? 70  HIS D CA  1 
ATOM   11495 C  C   . HIS D 3 174 ? 179.102 116.000 101.639 1.00 60.00  ? 70  HIS D C   1 
ATOM   11496 O  O   . HIS D 3 174 ? 180.047 115.465 101.046 1.00 60.00  ? 70  HIS D O   1 
ATOM   11497 C  CB  . HIS D 3 174 ? 178.641 117.351 99.583  1.00 60.00  ? 70  HIS D CB  1 
ATOM   11498 C  CG  . HIS D 3 174 ? 177.630 117.816 98.583  1.00 60.00  ? 70  HIS D CG  1 
ATOM   11499 N  ND1 . HIS D 3 174 ? 177.091 119.084 98.604  1.00 60.00  ? 70  HIS D ND1 1 
ATOM   11500 C  CD2 . HIS D 3 174 ? 177.051 117.178 97.539  1.00 60.00  ? 70  HIS D CD2 1 
ATOM   11501 C  CE1 . HIS D 3 174 ? 176.228 119.209 97.612  1.00 60.00  ? 70  HIS D CE1 1 
ATOM   11502 N  NE2 . HIS D 3 174 ? 176.184 118.066 96.951  1.00 60.00  ? 70  HIS D NE2 1 
ATOM   11503 N  N   . LYS D 3 175 ? 178.984 115.984 102.967 1.00 57.14  ? 71  LYS D N   1 
ATOM   11504 C  CA  . LYS D 3 175 ? 179.861 115.200 103.839 1.00 57.14  ? 71  LYS D CA  1 
ATOM   11505 C  C   . LYS D 3 175 ? 181.326 115.608 103.681 1.00 57.14  ? 71  LYS D C   1 
ATOM   11506 O  O   . LYS D 3 175 ? 182.200 114.782 103.409 1.00 57.14  ? 71  LYS D O   1 
ATOM   11507 C  CB  . LYS D 3 175 ? 179.678 113.700 103.590 1.00 57.14  ? 71  LYS D CB  1 
ATOM   11508 C  CG  . LYS D 3 175 ? 178.314 113.171 103.999 1.00 57.14  ? 71  LYS D CG  1 
ATOM   11509 C  CD  . LYS D 3 175 ? 178.201 111.675 103.759 1.00 57.14  ? 71  LYS D CD  1 
ATOM   11510 C  CE  . LYS D 3 175 ? 176.816 111.164 104.121 1.00 57.14  ? 71  LYS D CE  1 
ATOM   11511 N  NZ  . LYS D 3 175 ? 176.681 109.702 103.879 1.00 57.14  ? 71  LYS D NZ  1 
ATOM   11512 N  N   . HIS D 3 176 ? 181.586 116.904 103.858 1.00 60.36  ? 72  HIS D N   1 
ATOM   11513 C  CA  . HIS D 3 176 ? 182.942 117.455 103.888 1.00 60.36  ? 72  HIS D CA  1 
ATOM   11514 C  C   . HIS D 3 176 ? 183.737 117.120 102.630 1.00 60.36  ? 72  HIS D C   1 
ATOM   11515 O  O   . HIS D 3 176 ? 184.863 116.622 102.709 1.00 60.36  ? 72  HIS D O   1 
ATOM   11516 C  CB  . HIS D 3 176 ? 183.702 116.990 105.134 1.00 60.36  ? 72  HIS D CB  1 
ATOM   11517 C  CG  . HIS D 3 176 ? 183.159 117.543 106.414 1.00 60.36  ? 72  HIS D CG  1 
ATOM   11518 N  ND1 . HIS D 3 176 ? 182.161 116.919 107.130 1.00 60.36  ? 72  HIS D ND1 1 
ATOM   11519 C  CD2 . HIS D 3 176 ? 183.474 118.663 107.106 1.00 60.36  ? 72  HIS D CD2 1 
ATOM   11520 C  CE1 . HIS D 3 176 ? 181.885 117.630 108.209 1.00 60.36  ? 72  HIS D CE1 1 
ATOM   11521 N  NE2 . HIS D 3 176 ? 182.668 118.693 108.217 1.00 60.36  ? 72  HIS D NE2 1 
ATOM   11522 N  N   . ASN D 3 177 ? 183.162 117.385 101.460 1.00 68.92  ? 73  ASN D N   1 
ATOM   11523 C  CA  . ASN D 3 177 ? 183.893 117.298 100.201 1.00 68.92  ? 73  ASN D CA  1 
ATOM   11524 C  C   . ASN D 3 177 ? 183.777 118.648 99.503  1.00 68.92  ? 73  ASN D C   1 
ATOM   11525 O  O   . ASN D 3 177 ? 182.690 119.039 99.065  1.00 68.92  ? 73  ASN D O   1 
ATOM   11526 C  CB  . ASN D 3 177 ? 183.358 116.167 99.327  1.00 68.92  ? 73  ASN D CB  1 
ATOM   11527 C  CG  . ASN D 3 177 ? 184.262 115.870 98.143  1.00 68.92  ? 73  ASN D CG  1 
ATOM   11528 O  OD1 . ASN D 3 177 ? 185.282 116.531 97.943  1.00 68.92  ? 73  ASN D OD1 1 
ATOM   11529 N  ND2 . ASN D 3 177 ? 183.898 114.863 97.359  1.00 68.92  ? 73  ASN D ND2 1 
ATOM   11530 N  N   . ILE D 3 178 ? 184.900 119.360 99.408  1.00 73.98  ? 74  ILE D N   1 
ATOM   11531 C  CA  . ILE D 3 178 ? 184.880 120.720 98.882  1.00 73.98  ? 74  ILE D CA  1 
ATOM   11532 C  C   . ILE D 3 178 ? 184.500 120.725 97.406  1.00 73.98  ? 74  ILE D C   1 
ATOM   11533 O  O   . ILE D 3 178 ? 183.693 121.551 96.964  1.00 73.98  ? 74  ILE D O   1 
ATOM   11534 C  CB  . ILE D 3 178 ? 186.241 121.398 99.121  1.00 73.98  ? 74  ILE D CB  1 
ATOM   11535 C  CG1 . ILE D 3 178 ? 186.513 121.532 100.620 1.00 73.98  ? 74  ILE D CG1 1 
ATOM   11536 C  CG2 . ILE D 3 178 ? 186.294 122.756 98.443  1.00 73.98  ? 74  ILE D CG2 1 
ATOM   11537 C  CD1 . ILE D 3 178 ? 187.930 121.945 100.946 1.00 73.98  ? 74  ILE D CD1 1 
ATOM   11538 N  N   . GLU D 3 179 ? 185.055 119.794 96.627  1.00 85.45  ? 75  GLU D N   1 
ATOM   11539 C  CA  . GLU D 3 179 ? 184.893 119.850 95.177  1.00 85.45  ? 75  GLU D CA  1 
ATOM   11540 C  C   . GLU D 3 179 ? 183.449 119.597 94.758  1.00 85.45  ? 75  GLU D C   1 
ATOM   11541 O  O   . GLU D 3 179 ? 182.966 120.195 93.789  1.00 85.45  ? 75  GLU D O   1 
ATOM   11542 C  CB  . GLU D 3 179 ? 185.837 118.849 94.512  1.00 85.45  ? 75  GLU D CB  1 
ATOM   11543 C  CG  . GLU D 3 179 ? 187.308 119.205 94.675  1.00 85.45  ? 75  GLU D CG  1 
ATOM   11544 C  CD  . GLU D 3 179 ? 188.234 118.194 94.031  1.00 85.45  ? 75  GLU D CD  1 
ATOM   11545 O  OE1 . GLU D 3 179 ? 187.741 117.148 93.561  1.00 85.45  ? 75  GLU D OE1 1 
ATOM   11546 O  OE2 . GLU D 3 179 ? 189.458 118.445 93.996  1.00 85.45  ? 75  GLU D OE2 1 
ATOM   11547 N  N   . LYS D 3 180 ? 182.741 118.718 95.472  1.00 78.50  ? 76  LYS D N   1 
ATOM   11548 C  CA  . LYS D 3 180 ? 181.349 118.450 95.122  1.00 78.50  ? 76  LYS D CA  1 
ATOM   11549 C  C   . LYS D 3 180 ? 180.461 119.652 95.419  1.00 78.50  ? 76  LYS D C   1 
ATOM   11550 O  O   . LYS D 3 180 ? 179.589 120.002 94.613  1.00 78.50  ? 76  LYS D O   1 
ATOM   11551 C  CB  . LYS D 3 180 ? 180.843 117.210 95.860  1.00 78.50  ? 76  LYS D CB  1 
ATOM   11552 C  CG  . LYS D 3 180 ? 181.451 115.906 95.369  1.00 78.50  ? 76  LYS D CG  1 
ATOM   11553 C  CD  . LYS D 3 180 ? 180.850 114.707 96.088  1.00 78.50  ? 76  LYS D CD  1 
ATOM   11554 C  CE  . LYS D 3 180 ? 181.463 113.402 95.600  1.00 78.50  ? 76  LYS D CE  1 
ATOM   11555 N  NZ  . LYS D 3 180 ? 180.889 112.217 96.299  1.00 78.50  ? 76  LYS D NZ  1 
ATOM   11556 N  N   . SER D 3 181 ? 180.664 120.298 96.571  1.00 82.16  ? 77  SER D N   1 
ATOM   11557 C  CA  . SER D 3 181 ? 179.912 121.511 96.874  1.00 82.16  ? 77  SER D CA  1 
ATOM   11558 C  C   . SER D 3 181 ? 180.231 122.613 95.872  1.00 82.16  ? 77  SER D C   1 
ATOM   11559 O  O   . SER D 3 181 ? 179.336 123.350 95.442  1.00 82.16  ? 77  SER D O   1 
ATOM   11560 C  CB  . SER D 3 181 ? 180.209 121.973 98.299  1.00 82.16  ? 77  SER D CB  1 
ATOM   11561 O  OG  . SER D 3 181 ? 179.501 123.162 98.604  1.00 82.16  ? 77  SER D OG  1 
ATOM   11562 N  N   . LEU D 3 182 ? 181.504 122.734 95.485  1.00 86.66  ? 78  LEU D N   1 
ATOM   11563 C  CA  . LEU D 3 182 ? 181.872 123.665 94.422  1.00 86.66  ? 78  LEU D CA  1 
ATOM   11564 C  C   . LEU D 3 182 ? 181.149 123.326 93.126  1.00 86.66  ? 78  LEU D C   1 
ATOM   11565 O  O   . LEU D 3 182 ? 180.799 124.221 92.347  1.00 86.66  ? 78  LEU D O   1 
ATOM   11566 C  CB  . LEU D 3 182 ? 183.386 123.648 94.206  1.00 86.66  ? 78  LEU D CB  1 
ATOM   11567 C  CG  . LEU D 3 182 ? 184.293 124.176 95.320  1.00 86.66  ? 78  LEU D CG  1 
ATOM   11568 C  CD1 . LEU D 3 182 ? 185.752 123.915 94.978  1.00 86.66  ? 78  LEU D CD1 1 
ATOM   11569 C  CD2 . LEU D 3 182 ? 184.062 125.656 95.564  1.00 86.66  ? 78  LEU D CD2 1 
ATOM   11570 N  N   . ALA D 3 183 ? 180.915 122.035 92.877  1.00 89.72  ? 79  ALA D N   1 
ATOM   11571 C  CA  . ALA D 3 183 ? 180.193 121.635 91.675  1.00 89.72  ? 79  ALA D CA  1 
ATOM   11572 C  C   . ALA D 3 183 ? 178.710 121.964 91.787  1.00 89.72  ? 79  ALA D C   1 
ATOM   11573 O  O   . ALA D 3 183 ? 178.040 122.197 90.774  1.00 89.72  ? 79  ALA D O   1 
ATOM   11574 C  CB  . ALA D 3 183 ? 180.396 120.143 91.413  1.00 89.72  ? 79  ALA D CB  1 
ATOM   11575 N  N   . ASP D 3 184 ? 178.178 121.990 93.008  1.00 91.48  ? 80  ASP D N   1 
ATOM   11576 C  CA  . ASP D 3 184 ? 176.776 122.318 93.226  1.00 91.48  ? 80  ASP D CA  1 
ATOM   11577 C  C   . ASP D 3 184 ? 176.551 123.770 93.629  1.00 91.48  ? 80  ASP D C   1 
ATOM   11578 O  O   . ASP D 3 184 ? 175.442 124.112 94.052  1.00 91.48  ? 80  ASP D O   1 
ATOM   11579 C  CB  . ASP D 3 184 ? 176.171 121.393 94.287  1.00 91.48  ? 80  ASP D CB  1 
ATOM   11580 C  CG  . ASP D 3 184 ? 175.971 119.980 93.779  1.00 91.48  ? 80  ASP D CG  1 
ATOM   11581 O  OD1 . ASP D 3 184 ? 175.766 119.810 92.559  1.00 91.48  ? 80  ASP D OD1 1 
ATOM   11582 O  OD2 . ASP D 3 184 ? 176.014 119.039 94.597  1.00 91.48  ? 80  ASP D OD2 1 
ATOM   11583 N  N   . LEU D 3 185 ? 177.564 124.629 93.515  1.00 95.50  ? 81  LEU D N   1 
ATOM   11584 C  CA  . LEU D 3 185 ? 177.342 126.053 93.762  1.00 95.50  ? 81  LEU D CA  1 
ATOM   11585 C  C   . LEU D 3 185 ? 176.435 126.696 92.719  1.00 95.50  ? 81  LEU D C   1 
ATOM   11586 O  O   . LEU D 3 185 ? 175.504 127.421 93.112  1.00 95.50  ? 81  LEU D O   1 
ATOM   11587 C  CB  . LEU D 3 185 ? 178.684 126.788 93.858  1.00 95.50  ? 81  LEU D CB  1 
ATOM   11588 C  CG  . LEU D 3 185 ? 179.606 126.469 95.036  1.00 95.50  ? 81  LEU D CG  1 
ATOM   11589 C  CD1 . LEU D 3 185 ? 180.913 127.232 94.906  1.00 95.50  ? 81  LEU D CD1 1 
ATOM   11590 C  CD2 . LEU D 3 185 ? 178.935 126.772 96.364  1.00 95.50  ? 81  LEU D CD2 1 
ATOM   11591 N  N   . PRO D 3 186 ? 176.630 126.498 91.407  1.00 100.43 ? 82  PRO D N   1 
ATOM   11592 C  CA  . PRO D 3 186 ? 175.737 127.156 90.437  1.00 100.43 ? 82  PRO D CA  1 
ATOM   11593 C  C   . PRO D 3 186 ? 174.294 126.688 90.507  1.00 100.43 ? 82  PRO D C   1 
ATOM   11594 O  O   . PRO D 3 186 ? 173.409 127.407 90.025  1.00 100.43 ? 82  PRO D O   1 
ATOM   11595 C  CB  . PRO D 3 186 ? 176.365 126.803 89.081  1.00 100.43 ? 82  PRO D CB  1 
ATOM   11596 C  CG  . PRO D 3 186 ? 177.781 126.487 89.388  1.00 100.43 ? 82  PRO D CG  1 
ATOM   11597 C  CD  . PRO D 3 186 ? 177.747 125.818 90.724  1.00 100.43 ? 82  PRO D CD  1 
ATOM   11598 N  N   . ASN D 3 187 ? 174.024 125.513 91.081  1.00 105.06 ? 83  ASN D N   1 
ATOM   11599 C  CA  . ASN D 3 187 ? 172.655 125.012 91.139  1.00 105.06 ? 83  ASN D CA  1 
ATOM   11600 C  C   . ASN D 3 187 ? 171.761 125.858 92.035  1.00 105.06 ? 83  ASN D C   1 
ATOM   11601 O  O   . ASN D 3 187 ? 171.004 126.690 91.523  1.00 105.06 ? 83  ASN D O   1 
ATOM   11602 C  CB  . ASN D 3 187 ? 172.646 123.560 91.618  1.00 105.06 ? 83  ASN D CB  1 
ATOM   11603 C  CG  . ASN D 3 187 ? 173.337 122.624 90.648  1.00 105.06 ? 83  ASN D CG  1 
ATOM   11604 O  OD1 . ASN D 3 187 ? 174.369 122.034 90.965  1.00 105.06 ? 83  ASN D OD1 1 
ATOM   11605 N  ND2 . ASN D 3 187 ? 172.768 122.483 89.456  1.00 105.06 ? 83  ASN D ND2 1 
ATOM   11606 N  N   . PHE D 3 188 ? 171.825 125.666 93.350  1.00 94.61  ? 84  PHE D N   1 
ATOM   11607 C  CA  . PHE D 3 188 ? 171.024 126.424 94.300  1.00 94.61  ? 84  PHE D CA  1 
ATOM   11608 C  C   . PHE D 3 188 ? 171.493 127.871 94.301  1.00 94.61  ? 84  PHE D C   1 
ATOM   11609 O  O   . PHE D 3 188 ? 172.678 128.143 94.084  1.00 94.61  ? 84  PHE D O   1 
ATOM   11610 C  CB  . PHE D 3 188 ? 171.125 125.828 95.706  1.00 94.61  ? 84  PHE D CB  1 
ATOM   11611 C  CG  . PHE D 3 188 ? 170.517 124.460 95.830  1.00 94.61  ? 84  PHE D CG  1 
ATOM   11612 C  CD1 . PHE D 3 188 ? 169.149 124.307 95.978  1.00 94.61  ? 84  PHE D CD1 1 
ATOM   11613 C  CD2 . PHE D 3 188 ? 171.314 123.328 95.797  1.00 94.61  ? 84  PHE D CD2 1 
ATOM   11614 C  CE1 . PHE D 3 188 ? 168.586 123.049 96.091  1.00 94.61  ? 84  PHE D CE1 1 
ATOM   11615 C  CE2 . PHE D 3 188 ? 170.757 122.068 95.910  1.00 94.61  ? 84  PHE D CE2 1 
ATOM   11616 C  CZ  . PHE D 3 188 ? 169.392 121.928 96.058  1.00 94.61  ? 84  PHE D CZ  1 
ATOM   11617 N  N   . THR D 3 189 ? 170.566 128.790 94.543  1.00 92.12  ? 85  THR D N   1 
ATOM   11618 C  CA  . THR D 3 189 ? 170.902 130.209 94.523  1.00 92.12  ? 85  THR D CA  1 
ATOM   11619 C  C   . THR D 3 189 ? 170.538 130.854 95.856  1.00 92.12  ? 85  THR D C   1 
ATOM   11620 O  O   . THR D 3 189 ? 169.568 130.430 96.497  1.00 92.12  ? 85  THR D O   1 
ATOM   11621 C  CB  . THR D 3 189 ? 170.179 130.920 93.381  1.00 92.12  ? 85  THR D CB  1 
ATOM   11622 O  OG1 . THR D 3 189 ? 170.618 132.282 93.301  1.00 92.12  ? 85  THR D OG1 1 
ATOM   11623 C  CG2 . THR D 3 189 ? 168.667 130.883 93.578  1.00 92.12  ? 85  THR D CG2 1 
ATOM   11624 N  N   . PRO D 3 190 ? 171.297 131.850 96.320  1.00 87.45  ? 86  PRO D N   1 
ATOM   11625 C  CA  . PRO D 3 190 ? 170.900 132.592 97.536  1.00 87.45  ? 86  PRO D CA  1 
ATOM   11626 C  C   . PRO D 3 190 ? 169.703 133.495 97.250  1.00 87.45  ? 86  PRO D C   1 
ATOM   11627 O  O   . PRO D 3 190 ? 169.826 134.632 96.796  1.00 87.45  ? 86  PRO D O   1 
ATOM   11628 C  CB  . PRO D 3 190 ? 172.165 133.385 97.875  1.00 87.45  ? 86  PRO D CB  1 
ATOM   11629 C  CG  . PRO D 3 190 ? 172.857 133.564 96.567  1.00 87.45  ? 86  PRO D CG  1 
ATOM   11630 C  CD  . PRO D 3 190 ? 172.587 132.316 95.780  1.00 87.45  ? 86  PRO D CD  1 
ATOM   11631 N  N   . PHE D 3 191 ? 168.510 132.952 97.533  1.00 91.36  ? 87  PHE D N   1 
ATOM   11632 C  CA  . PHE D 3 191 ? 167.200 133.507 97.196  1.00 91.36  ? 87  PHE D CA  1 
ATOM   11633 C  C   . PHE D 3 191 ? 167.139 135.019 97.382  1.00 91.36  ? 87  PHE D C   1 
ATOM   11634 O  O   . PHE D 3 191 ? 167.010 135.506 98.513  1.00 91.36  ? 87  PHE D O   1 
ATOM   11635 C  CB  . PHE D 3 191 ? 166.114 132.835 98.037  1.00 91.36  ? 87  PHE D CB  1 
ATOM   11636 C  CG  . PHE D 3 191 ? 165.923 131.378 97.727  1.00 91.36  ? 87  PHE D CG  1 
ATOM   11637 C  CD1 . PHE D 3 191 ? 165.178 130.981 96.629  1.00 91.36  ? 87  PHE D CD1 1 
ATOM   11638 C  CD2 . PHE D 3 191 ? 166.488 130.404 98.534  1.00 91.36  ? 87  PHE D CD2 1 
ATOM   11639 C  CE1 . PHE D 3 191 ? 165.000 129.640 96.342  1.00 91.36  ? 87  PHE D CE1 1 
ATOM   11640 C  CE2 . PHE D 3 191 ? 166.314 129.062 98.252  1.00 91.36  ? 87  PHE D CE2 1 
ATOM   11641 C  CZ  . PHE D 3 191 ? 165.569 128.680 97.154  1.00 91.36  ? 87  PHE D CZ  1 
ATOM   11642 N  N   . PRO D 3 192 ? 167.229 135.789 96.302  1.00 88.99  ? 88  PRO D N   1 
ATOM   11643 C  CA  . PRO D 3 192 ? 167.226 137.248 96.418  1.00 88.99  ? 88  PRO D CA  1 
ATOM   11644 C  C   . PRO D 3 192 ? 165.823 137.811 96.607  1.00 88.99  ? 88  PRO D C   1 
ATOM   11645 O  O   . PRO D 3 192 ? 165.145 138.212 95.658  1.00 88.99  ? 88  PRO D O   1 
ATOM   11646 C  CB  . PRO D 3 192 ? 167.818 137.703 95.076  1.00 88.99  ? 88  PRO D CB  1 
ATOM   11647 C  CG  . PRO D 3 192 ? 167.430 136.622 94.125  1.00 88.99  ? 88  PRO D CG  1 
ATOM   11648 C  CD  . PRO D 3 192 ? 167.449 135.340 94.915  1.00 88.99  ? 88  PRO D CD  1 
ATOM   11649 N  N   . ASP D 3 193 ? 165.398 137.836 97.869  1.00 91.30  ? 89  ASP D N   1 
ATOM   11650 C  CA  . ASP D 3 193 ? 164.112 138.424 98.222  1.00 91.30  ? 89  ASP D CA  1 
ATOM   11651 C  C   . ASP D 3 193 ? 164.150 139.927 97.980  1.00 91.30  ? 89  ASP D C   1 
ATOM   11652 O  O   . ASP D 3 193 ? 164.161 140.717 98.929  1.00 91.30  ? 89  ASP D O   1 
ATOM   11653 C  CB  . ASP D 3 193 ? 163.759 138.118 99.680  1.00 91.30  ? 89  ASP D CB  1 
ATOM   11654 C  CG  . ASP D 3 193 ? 163.476 136.648 99.913  1.00 91.30  ? 89  ASP D CG  1 
ATOM   11655 O  OD1 . ASP D 3 193 ? 163.018 135.973 98.968  1.00 91.30  ? 89  ASP D OD1 1 
ATOM   11656 O  OD2 . ASP D 3 193 ? 163.714 136.167 101.040 1.00 91.30  ? 89  ASP D OD2 1 
ATOM   11657 N  N   . GLU D 3 194 ? 164.167 140.327 96.708  1.00 85.77  ? 90  GLU D N   1 
ATOM   11658 C  CA  . GLU D 3 194 ? 164.391 141.721 96.325  1.00 85.77  ? 90  GLU D CA  1 
ATOM   11659 C  C   . GLU D 3 194 ? 163.134 142.540 96.602  1.00 85.77  ? 90  GLU D C   1 
ATOM   11660 O  O   . GLU D 3 194 ? 162.089 142.384 95.966  1.00 85.77  ? 90  GLU D O   1 
ATOM   11661 C  CB  . GLU D 3 194 ? 164.802 141.816 94.860  1.00 85.77  ? 90  GLU D CB  1 
ATOM   11662 C  CG  . GLU D 3 194 ? 166.177 141.244 94.564  1.00 85.77  ? 90  GLU D CG  1 
ATOM   11663 C  CD  . GLU D 3 194 ? 166.554 141.367 93.103  1.00 85.77  ? 90  GLU D CD  1 
ATOM   11664 O  OE1 . GLU D 3 194 ? 165.692 141.785 92.302  1.00 85.77  ? 90  GLU D OE1 1 
ATOM   11665 O  OE2 . GLU D 3 194 ? 167.710 141.048 92.754  1.00 85.77  ? 90  GLU D OE2 1 
ATOM   11666 N  N   . TRP D 3 195 ? 163.246 143.428 97.585  1.00 58.50  ? 91  TRP D N   1 
ATOM   11667 C  CA  . TRP D 3 195 ? 162.250 144.469 97.819  1.00 58.50  ? 91  TRP D CA  1 
ATOM   11668 C  C   . TRP D 3 195 ? 162.458 145.539 96.757  1.00 58.50  ? 91  TRP D C   1 
ATOM   11669 O  O   . TRP D 3 195 ? 163.358 146.374 96.866  1.00 58.50  ? 91  TRP D O   1 
ATOM   11670 C  CB  . TRP D 3 195 ? 162.393 145.035 99.227  1.00 58.50  ? 91  TRP D CB  1 
ATOM   11671 C  CG  . TRP D 3 195 ? 162.000 144.073 100.314 1.00 58.50  ? 91  TRP D CG  1 
ATOM   11672 C  CD1 . TRP D 3 195 ? 162.805 143.164 100.930 1.00 58.50  ? 91  TRP D CD1 1 
ATOM   11673 C  CD2 . TRP D 3 195 ? 160.719 143.966 100.947 1.00 58.50  ? 91  TRP D CD2 1 
ATOM   11674 N  NE1 . TRP D 3 195 ? 162.100 142.476 101.887 1.00 58.50  ? 91  TRP D NE1 1 
ATOM   11675 C  CE2 . TRP D 3 195 ? 160.816 142.953 101.919 1.00 58.50  ? 91  TRP D CE2 1 
ATOM   11676 C  CE3 . TRP D 3 195 ? 159.498 144.621 100.779 1.00 58.50  ? 91  TRP D CE3 1 
ATOM   11677 C  CZ2 . TRP D 3 195 ? 159.738 142.580 102.717 1.00 58.50  ? 91  TRP D CZ2 1 
ATOM   11678 C  CZ3 . TRP D 3 195 ? 158.429 144.250 101.572 1.00 58.50  ? 91  TRP D CZ3 1 
ATOM   11679 C  CH2 . TRP D 3 195 ? 158.558 143.244 102.533 1.00 58.50  ? 91  TRP D CH2 1 
ATOM   11680 N  N   . THR D 3 196 ? 161.630 145.512 95.715  1.00 70.03  ? 92  THR D N   1 
ATOM   11681 C  CA  . THR D 3 196 ? 161.825 146.398 94.578  1.00 70.03  ? 92  THR D CA  1 
ATOM   11682 C  C   . THR D 3 196 ? 161.454 147.836 94.939  1.00 70.03  ? 92  THR D C   1 
ATOM   11683 O  O   . THR D 3 196 ? 161.331 148.206 96.111  1.00 70.03  ? 92  THR D O   1 
ATOM   11684 C  CB  . THR D 3 196 ? 161.002 145.926 93.380  1.00 70.03  ? 92  THR D CB  1 
ATOM   11685 O  OG1 . THR D 3 196 ? 159.610 145.945 93.716  1.00 70.03  ? 92  THR D OG1 1 
ATOM   11686 C  CG2 . THR D 3 196 ? 161.403 144.513 92.980  1.00 70.03  ? 92  THR D CG2 1 
ATOM   11687 N  N   . VAL D 3 197 ? 161.272 148.654 93.899  1.00 73.80  ? 93  VAL D N   1 
ATOM   11688 C  CA  . VAL D 3 197 ? 160.989 150.073 94.105  1.00 73.80  ? 93  VAL D CA  1 
ATOM   11689 C  C   . VAL D 3 197 ? 159.671 150.257 94.844  1.00 73.80  ? 93  VAL D C   1 
ATOM   11690 O  O   . VAL D 3 197 ? 159.617 150.917 95.889  1.00 73.80  ? 93  VAL D O   1 
ATOM   11691 C  CB  . VAL D 3 197 ? 160.991 150.820 92.758  1.00 73.80  ? 93  VAL D CB  1 
ATOM   11692 C  CG1 . VAL D 3 197 ? 160.582 152.272 92.958  1.00 73.80  ? 93  VAL D CG1 1 
ATOM   11693 C  CG2 . VAL D 3 197 ? 162.360 150.732 92.105  1.00 73.80  ? 93  VAL D CG2 1 
ATOM   11694 N  N   . GLU D 3 198 ? 158.590 149.673 94.321  1.00 77.86  ? 94  GLU D N   1 
ATOM   11695 C  CA  . GLU D 3 198 ? 157.287 149.821 94.961  1.00 77.86  ? 94  GLU D CA  1 
ATOM   11696 C  C   . GLU D 3 198 ? 157.298 149.255 96.376  1.00 77.86  ? 94  GLU D C   1 
ATOM   11697 O  O   . GLU D 3 198 ? 156.666 149.812 97.280  1.00 77.86  ? 94  GLU D O   1 
ATOM   11698 C  CB  . GLU D 3 198 ? 156.206 149.142 94.120  1.00 77.86  ? 94  GLU D CB  1 
ATOM   11699 C  CG  . GLU D 3 198 ? 155.939 149.816 92.781  1.00 77.86  ? 94  GLU D CG  1 
ATOM   11700 C  CD  . GLU D 3 198 ? 156.908 149.378 91.699  1.00 77.86  ? 94  GLU D CD  1 
ATOM   11701 O  OE1 . GLU D 3 198 ? 157.746 148.492 91.972  1.00 77.86  ? 94  GLU D OE1 1 
ATOM   11702 O  OE2 . GLU D 3 198 ? 156.832 149.922 90.577  1.00 77.86  ? 94  GLU D OE2 1 
ATOM   11703 N  N   . ASP D 3 199 ? 158.023 148.157 96.590  1.00 66.90  ? 95  ASP D N   1 
ATOM   11704 C  CA  . ASP D 3 199 ? 158.053 147.541 97.912  1.00 66.90  ? 95  ASP D CA  1 
ATOM   11705 C  C   . ASP D 3 199 ? 158.709 148.457 98.940  1.00 66.90  ? 95  ASP D C   1 
ATOM   11706 O  O   . ASP D 3 199 ? 158.104 148.783 99.969  1.00 66.90  ? 95  ASP D O   1 
ATOM   11707 C  CB  . ASP D 3 199 ? 158.779 146.199 97.839  1.00 66.90  ? 95  ASP D CB  1 
ATOM   11708 C  CG  . ASP D 3 199 ? 157.999 145.158 97.060  1.00 66.90  ? 95  ASP D CG  1 
ATOM   11709 O  OD1 . ASP D 3 199 ? 156.752 145.235 97.049  1.00 66.90  ? 95  ASP D OD1 1 
ATOM   11710 O  OD2 . ASP D 3 199 ? 158.631 144.263 96.460  1.00 66.90  ? 95  ASP D OD2 1 
ATOM   11711 N  N   . LYS D 3 200 ? 159.943 148.892 98.673  1.00 60.54  ? 96  LYS D N   1 
ATOM   11712 C  CA  . LYS D 3 200 ? 160.657 149.725 99.636  1.00 60.54  ? 96  LYS D CA  1 
ATOM   11713 C  C   . LYS D 3 200 ? 159.999 151.091 99.793  1.00 60.54  ? 96  LYS D C   1 
ATOM   11714 O  O   . LYS D 3 200 ? 159.926 151.626 100.905 1.00 60.54  ? 96  LYS D O   1 
ATOM   11715 C  CB  . LYS D 3 200 ? 162.118 149.884 99.218  1.00 60.54  ? 96  LYS D CB  1 
ATOM   11716 C  CG  . LYS D 3 200 ? 162.950 148.625 99.354  1.00 60.54  ? 96  LYS D CG  1 
ATOM   11717 C  CD  . LYS D 3 200 ? 164.400 148.893 98.991  1.00 60.54  ? 96  LYS D CD  1 
ATOM   11718 C  CE  . LYS D 3 200 ? 165.251 147.644 99.137  1.00 60.54  ? 96  LYS D CE  1 
ATOM   11719 N  NZ  . LYS D 3 200 ? 166.671 147.901 98.774  1.00 60.54  ? 96  LYS D NZ  1 
ATOM   11720 N  N   . VAL D 3 201 ? 159.519 151.675 98.692  1.00 67.05  ? 97  VAL D N   1 
ATOM   11721 C  CA  . VAL D 3 201 ? 158.925 153.008 98.768  1.00 67.05  ? 97  VAL D CA  1 
ATOM   11722 C  C   . VAL D 3 201 ? 157.600 152.964 99.519  1.00 67.05  ? 97  VAL D C   1 
ATOM   11723 O  O   . VAL D 3 201 ? 157.322 153.824 100.364 1.00 67.05  ? 97  VAL D O   1 
ATOM   11724 C  CB  . VAL D 3 201 ? 158.767 153.610 97.359  1.00 67.05  ? 97  VAL D CB  1 
ATOM   11725 C  CG1 . VAL D 3 201 ? 157.973 154.903 97.422  1.00 67.05  ? 97  VAL D CG1 1 
ATOM   11726 C  CG2 . VAL D 3 201 ? 160.136 153.873 96.748  1.00 67.05  ? 97  VAL D CG2 1 
ATOM   11727 N  N   . LEU D 3 202 ? 156.761 151.964 99.231  1.00 66.41  ? 98  LEU D N   1 
ATOM   11728 C  CA  . LEU D 3 202 ? 155.522 151.818 99.989  1.00 66.41  ? 98  LEU D CA  1 
ATOM   11729 C  C   . LEU D 3 202 ? 155.806 151.501 101.452 1.00 66.41  ? 98  LEU D C   1 
ATOM   11730 O  O   . LEU D 3 202 ? 155.044 151.903 102.340 1.00 66.41  ? 98  LEU D O   1 
ATOM   11731 C  CB  . LEU D 3 202 ? 154.633 150.742 99.367  1.00 66.41  ? 98  LEU D CB  1 
ATOM   11732 C  CG  . LEU D 3 202 ? 153.966 151.081 98.031  1.00 66.41  ? 98  LEU D CG  1 
ATOM   11733 C  CD1 . LEU D 3 202 ? 153.239 149.866 97.475  1.00 66.41  ? 98  LEU D CD1 1 
ATOM   11734 C  CD2 . LEU D 3 202 ? 153.014 152.255 98.185  1.00 66.41  ? 98  LEU D CD2 1 
ATOM   11735 N  N   . PHE D 3 203 ? 156.900 150.784 101.727 1.00 49.08  ? 99  PHE D N   1 
ATOM   11736 C  CA  . PHE D 3 203 ? 157.287 150.558 103.115 1.00 49.08  ? 99  PHE D CA  1 
ATOM   11737 C  C   . PHE D 3 203 ? 157.682 151.865 103.791 1.00 49.08  ? 99  PHE D C   1 
ATOM   11738 O  O   . PHE D 3 203 ? 157.391 152.074 104.974 1.00 49.08  ? 99  PHE D O   1 
ATOM   11739 C  CB  . PHE D 3 203 ? 158.430 149.546 103.195 1.00 49.08  ? 99  PHE D CB  1 
ATOM   11740 C  CG  . PHE D 3 203 ? 158.845 149.214 104.601 1.00 49.08  ? 99  PHE D CG  1 
ATOM   11741 C  CD1 . PHE D 3 203 ? 158.068 148.380 105.387 1.00 49.08  ? 99  PHE D CD1 1 
ATOM   11742 C  CD2 . PHE D 3 203 ? 160.007 149.740 105.139 1.00 49.08  ? 99  PHE D CD2 1 
ATOM   11743 C  CE1 . PHE D 3 203 ? 158.444 148.075 106.681 1.00 49.08  ? 99  PHE D CE1 1 
ATOM   11744 C  CE2 . PHE D 3 203 ? 160.388 149.438 106.433 1.00 49.08  ? 99  PHE D CE2 1 
ATOM   11745 C  CZ  . PHE D 3 203 ? 159.605 148.605 107.204 1.00 49.08  ? 99  PHE D CZ  1 
ATOM   11746 N  N   . GLU D 3 204 ? 158.345 152.760 103.054 1.00 61.17  ? 100 GLU D N   1 
ATOM   11747 C  CA  . GLU D 3 204 ? 158.684 154.064 103.613 1.00 61.17  ? 100 GLU D CA  1 
ATOM   11748 C  C   . GLU D 3 204 ? 157.436 154.911 103.823 1.00 61.17  ? 100 GLU D C   1 
ATOM   11749 O  O   . GLU D 3 204 ? 157.383 155.735 104.744 1.00 61.17  ? 100 GLU D O   1 
ATOM   11750 C  CB  . GLU D 3 204 ? 159.679 154.787 102.706 1.00 61.17  ? 100 GLU D CB  1 
ATOM   11751 C  CG  . GLU D 3 204 ? 161.053 154.143 102.654 1.00 61.17  ? 100 GLU D CG  1 
ATOM   11752 C  CD  . GLU D 3 204 ? 162.016 154.898 101.760 1.00 61.17  ? 100 GLU D CD  1 
ATOM   11753 O  OE1 . GLU D 3 204 ? 161.577 155.852 101.083 1.00 61.17  ? 100 GLU D OE1 1 
ATOM   11754 O  OE2 . GLU D 3 204 ? 163.212 154.539 101.735 1.00 61.17  ? 100 GLU D OE2 1 
ATOM   11755 N  N   . GLN D 3 205 ? 156.420 154.727 102.975 1.00 65.90  ? 101 GLN D N   1 
ATOM   11756 C  CA  . GLN D 3 205 ? 155.161 155.436 103.175 1.00 65.90  ? 101 GLN D CA  1 
ATOM   11757 C  C   . GLN D 3 205 ? 154.433 154.918 104.408 1.00 65.90  ? 101 GLN D C   1 
ATOM   11758 O  O   . GLN D 3 205 ? 153.843 155.697 105.165 1.00 65.90  ? 101 GLN D O   1 
ATOM   11759 C  CB  . GLN D 3 205 ? 154.275 155.306 101.937 1.00 65.90  ? 101 GLN D CB  1 
ATOM   11760 C  CG  . GLN D 3 205 ? 154.818 156.005 100.701 1.00 65.90  ? 101 GLN D CG  1 
ATOM   11761 C  CD  . GLN D 3 205 ? 153.896 155.869 99.505  1.00 65.90  ? 101 GLN D CD  1 
ATOM   11762 O  OE1 . GLN D 3 205 ? 152.859 155.210 99.577  1.00 65.90  ? 101 GLN D OE1 1 
ATOM   11763 N  NE2 . GLN D 3 205 ? 154.272 156.494 98.394  1.00 65.90  ? 101 GLN D NE2 1 
ATOM   11764 N  N   . ALA D 3 206 ? 154.464 153.602 104.629 1.00 52.27  ? 102 ALA D N   1 
ATOM   11765 C  CA  . ALA D 3 206 ? 153.839 153.043 105.822 1.00 52.27  ? 102 ALA D CA  1 
ATOM   11766 C  C   . ALA D 3 206 ? 154.591 153.454 107.080 1.00 52.27  ? 102 ALA D C   1 
ATOM   11767 O  O   . ALA D 3 206 ? 153.980 153.693 108.129 1.00 52.27  ? 102 ALA D O   1 
ATOM   11768 C  CB  . ALA D 3 206 ? 153.768 151.521 105.714 1.00 52.27  ? 102 ALA D CB  1 
ATOM   11769 N  N   . PHE D 3 207 ? 155.919 153.548 106.995 1.00 46.48  ? 103 PHE D N   1 
ATOM   11770 C  CA  . PHE D 3 207 ? 156.710 153.893 108.171 1.00 46.48  ? 103 PHE D CA  1 
ATOM   11771 C  C   . PHE D 3 207 ? 156.697 155.395 108.425 1.00 46.48  ? 103 PHE D C   1 
ATOM   11772 O  O   . PHE D 3 207 ? 157.008 155.848 109.532 1.00 46.48  ? 103 PHE D O   1 
ATOM   11773 C  CB  . PHE D 3 207 ? 158.141 153.382 108.005 1.00 46.48  ? 103 PHE D CB  1 
ATOM   11774 C  CG  . PHE D 3 207 ? 159.018 153.646 109.193 1.00 46.48  ? 103 PHE D CG  1 
ATOM   11775 C  CD1 . PHE D 3 207 ? 158.871 152.909 110.355 1.00 46.48  ? 103 PHE D CD1 1 
ATOM   11776 C  CD2 . PHE D 3 207 ? 159.992 154.629 109.147 1.00 46.48  ? 103 PHE D CD2 1 
ATOM   11777 C  CE1 . PHE D 3 207 ? 159.675 153.151 111.451 1.00 46.48  ? 103 PHE D CE1 1 
ATOM   11778 C  CE2 . PHE D 3 207 ? 160.801 154.874 110.239 1.00 46.48  ? 103 PHE D CE2 1 
ATOM   11779 C  CZ  . PHE D 3 207 ? 160.643 154.132 111.392 1.00 46.48  ? 103 PHE D CZ  1 
ATOM   11780 N  N   . SER D 3 208 ? 156.334 156.186 107.413 1.00 58.61  ? 104 SER D N   1 
ATOM   11781 C  CA  . SER D 3 208 ? 156.287 157.632 107.598 1.00 58.61  ? 104 SER D CA  1 
ATOM   11782 C  C   . SER D 3 208 ? 154.871 158.106 107.904 1.00 58.61  ? 104 SER D C   1 
ATOM   11783 O  O   . SER D 3 208 ? 154.680 159.215 108.417 1.00 58.61  ? 104 SER D O   1 
ATOM   11784 C  CB  . SER D 3 208 ? 156.836 158.338 106.359 1.00 58.61  ? 104 SER D CB  1 
ATOM   11785 O  OG  . SER D 3 208 ? 156.774 159.746 106.504 1.00 58.61  ? 104 SER D OG  1 
ATOM   11786 N  N   . PHE D 3 209 ? 153.867 157.283 107.597 1.00 66.05  ? 105 PHE D N   1 
ATOM   11787 C  CA  . PHE D 3 209 ? 152.485 157.656 107.881 1.00 66.05  ? 105 PHE D CA  1 
ATOM   11788 C  C   . PHE D 3 209 ? 151.857 156.732 108.919 1.00 66.05  ? 105 PHE D C   1 
ATOM   11789 O  O   . PHE D 3 209 ? 150.649 156.801 109.170 1.00 66.05  ? 105 PHE D O   1 
ATOM   11790 C  CB  . PHE D 3 209 ? 151.661 157.652 106.592 1.00 66.05  ? 105 PHE D CB  1 
ATOM   11791 C  CG  . PHE D 3 209 ? 152.008 158.765 105.647 1.00 66.05  ? 105 PHE D CG  1 
ATOM   11792 C  CD1 . PHE D 3 209 ? 151.496 160.037 105.841 1.00 66.05  ? 105 PHE D CD1 1 
ATOM   11793 C  CD2 . PHE D 3 209 ? 152.843 158.542 104.566 1.00 66.05  ? 105 PHE D CD2 1 
ATOM   11794 C  CE1 . PHE D 3 209 ? 151.812 161.065 104.975 1.00 66.05  ? 105 PHE D CE1 1 
ATOM   11795 C  CE2 . PHE D 3 209 ? 153.163 159.566 103.696 1.00 66.05  ? 105 PHE D CE2 1 
ATOM   11796 C  CZ  . PHE D 3 209 ? 152.646 160.830 103.901 1.00 66.05  ? 105 PHE D CZ  1 
ATOM   11797 N  N   . HIS D 3 210 ? 152.658 155.863 109.531 1.00 51.37  ? 106 HIS D N   1 
ATOM   11798 C  CA  . HIS D 3 210 ? 152.175 154.952 110.560 1.00 51.37  ? 106 HIS D CA  1 
ATOM   11799 C  C   . HIS D 3 210 ? 153.138 154.800 111.728 1.00 51.37  ? 106 HIS D C   1 
ATOM   11800 O  O   . HIS D 3 210 ? 152.849 155.304 112.819 1.00 51.37  ? 106 HIS D O   1 
ATOM   11801 C  CB  . HIS D 3 210 ? 151.877 153.577 109.953 1.00 51.37  ? 106 HIS D CB  1 
ATOM   11802 C  CG  . HIS D 3 210 ? 150.711 153.575 109.015 1.00 51.37  ? 106 HIS D CG  1 
ATOM   11803 N  ND1 . HIS D 3 210 ? 149.405 153.618 109.455 1.00 51.37  ? 106 HIS D ND1 1 
ATOM   11804 C  CD2 . HIS D 3 210 ? 150.652 153.544 107.663 1.00 51.37  ? 106 HIS D CD2 1 
ATOM   11805 C  CE1 . HIS D 3 210 ? 148.592 153.607 108.413 1.00 51.37  ? 106 HIS D CE1 1 
ATOM   11806 N  NE2 . HIS D 3 210 ? 149.323 153.566 107.314 1.00 51.37  ? 106 HIS D NE2 1 
ATOM   11807 N  N   . GLY D 3 211 ? 154.266 154.122 111.537 1.00 39.36  ? 107 GLY D N   1 
ATOM   11808 C  CA  . GLY D 3 211 ? 155.211 153.966 112.630 1.00 39.36  ? 107 GLY D CA  1 
ATOM   11809 C  C   . GLY D 3 211 ? 155.699 152.534 112.745 1.00 39.36  ? 107 GLY D C   1 
ATOM   11810 O  O   . GLY D 3 211 ? 156.147 151.922 111.769 1.00 39.36  ? 107 GLY D O   1 
ATOM   11811 N  N   . LYS D 3 212 ? 155.615 151.990 113.958 1.00 26.83  ? 108 LYS D N   1 
ATOM   11812 C  CA  . LYS D 3 212 ? 156.045 150.627 114.234 1.00 26.83  ? 108 LYS D CA  1 
ATOM   11813 C  C   . LYS D 3 212 ? 154.881 149.676 114.470 1.00 26.83  ? 108 LYS D C   1 
ATOM   11814 O  O   . LYS D 3 212 ? 155.062 148.637 115.116 1.00 26.83  ? 108 LYS D O   1 
ATOM   11815 C  CB  . LYS D 3 212 ? 156.992 150.599 115.434 1.00 26.83  ? 108 LYS D CB  1 
ATOM   11816 C  CG  . LYS D 3 212 ? 158.347 151.222 115.172 1.00 26.83  ? 108 LYS D CG  1 
ATOM   11817 C  CD  . LYS D 3 212 ? 159.237 151.098 116.393 1.00 26.83  ? 108 LYS D CD  1 
ATOM   11818 C  CE  . LYS D 3 212 ? 160.588 151.742 116.163 1.00 26.83  ? 108 LYS D CE  1 
ATOM   11819 N  NZ  . LYS D 3 212 ? 161.465 151.614 117.355 1.00 26.83  ? 108 LYS D NZ  1 
ATOM   11820 N  N   . THR D 3 213 ? 153.692 150.006 113.975 1.00 29.23  ? 109 THR D N   1 
ATOM   11821 C  CA  . THR D 3 213 ? 152.572 149.070 114.000 1.00 29.23  ? 109 THR D CA  1 
ATOM   11822 C  C   . THR D 3 213 ? 152.609 148.303 112.685 1.00 29.23  ? 109 THR D C   1 
ATOM   11823 O  O   . THR D 3 213 ? 151.966 148.674 111.702 1.00 29.23  ? 109 THR D O   1 
ATOM   11824 C  CB  . THR D 3 213 ? 151.248 149.798 114.196 1.00 29.23  ? 109 THR D CB  1 
ATOM   11825 O  OG1 . THR D 3 213 ? 151.296 150.558 115.409 1.00 29.23  ? 109 THR D OG1 1 
ATOM   11826 C  CG2 . THR D 3 213 ? 150.105 148.797 114.288 1.00 29.23  ? 109 THR D CG2 1 
ATOM   11827 N  N   . PHE D 3 214 ? 153.392 147.222 112.665 1.00 22.67  ? 110 PHE D N   1 
ATOM   11828 C  CA  . PHE D 3 214 ? 153.558 146.441 111.445 1.00 22.67  ? 110 PHE D CA  1 
ATOM   11829 C  C   . PHE D 3 214 ? 152.248 145.831 110.967 1.00 22.67  ? 110 PHE D C   1 
ATOM   11830 O  O   . PHE D 3 214 ? 152.139 145.468 109.790 1.00 22.67  ? 110 PHE D O   1 
ATOM   11831 C  CB  . PHE D 3 214 ? 154.606 145.350 111.663 1.00 22.67  ? 110 PHE D CB  1 
ATOM   11832 C  CG  . PHE D 3 214 ? 155.995 145.883 111.878 1.00 22.67  ? 110 PHE D CG  1 
ATOM   11833 C  CD1 . PHE D 3 214 ? 156.773 146.281 110.806 1.00 22.67  ? 110 PHE D CD1 1 
ATOM   11834 C  CD2 . PHE D 3 214 ? 156.522 145.987 113.152 1.00 22.67  ? 110 PHE D CD2 1 
ATOM   11835 C  CE1 . PHE D 3 214 ? 158.050 146.773 111.002 1.00 22.67  ? 110 PHE D CE1 1 
ATOM   11836 C  CE2 . PHE D 3 214 ? 157.799 146.478 113.352 1.00 22.67  ? 110 PHE D CE2 1 
ATOM   11837 C  CZ  . PHE D 3 214 ? 158.562 146.871 112.276 1.00 22.67  ? 110 PHE D CZ  1 
ATOM   11838 N  N   . HIS D 3 215 ? 151.252 145.717 111.849 1.00 34.66  ? 111 HIS D N   1 
ATOM   11839 C  CA  . HIS D 3 215 ? 149.924 145.306 111.411 1.00 34.66  ? 111 HIS D CA  1 
ATOM   11840 C  C   . HIS D 3 215 ? 149.308 146.345 110.480 1.00 34.66  ? 111 HIS D C   1 
ATOM   11841 O  O   . HIS D 3 215 ? 148.587 145.993 109.540 1.00 34.66  ? 111 HIS D O   1 
ATOM   11842 C  CB  . HIS D 3 215 ? 149.023 145.067 112.620 1.00 34.66  ? 111 HIS D CB  1 
ATOM   11843 C  CG  . HIS D 3 215 ? 147.642 144.618 112.262 1.00 34.66  ? 111 HIS D CG  1 
ATOM   11844 N  ND1 . HIS D 3 215 ? 147.366 143.343 111.819 1.00 34.66  ? 111 HIS D ND1 1 
ATOM   11845 C  CD2 . HIS D 3 215 ? 146.459 145.277 112.275 1.00 34.66  ? 111 HIS D CD2 1 
ATOM   11846 C  CE1 . HIS D 3 215 ? 146.071 143.234 111.578 1.00 34.66  ? 111 HIS D CE1 1 
ATOM   11847 N  NE2 . HIS D 3 215 ? 145.498 144.393 111.847 1.00 34.66  ? 111 HIS D NE2 1 
ATOM   11848 N  N   . ARG D 3 216 ? 149.578 147.630 110.728 1.00 37.34  ? 112 ARG D N   1 
ATOM   11849 C  CA  . ARG D 3 216 ? 149.118 148.668 109.812 1.00 37.34  ? 112 ARG D CA  1 
ATOM   11850 C  C   . ARG D 3 216 ? 149.952 148.700 108.540 1.00 37.34  ? 112 ARG D C   1 
ATOM   11851 O  O   . ARG D 3 216 ? 149.412 148.937 107.454 1.00 37.34  ? 112 ARG D O   1 
ATOM   11852 C  CB  . ARG D 3 216 ? 149.149 150.036 110.492 1.00 37.34  ? 112 ARG D CB  1 
ATOM   11853 C  CG  . ARG D 3 216 ? 148.106 150.225 111.577 1.00 37.34  ? 112 ARG D CG  1 
ATOM   11854 C  CD  . ARG D 3 216 ? 148.202 151.617 112.174 1.00 37.34  ? 112 ARG D CD  1 
ATOM   11855 N  NE  . ARG D 3 216 ? 147.222 151.833 113.234 1.00 37.34  ? 112 ARG D NE  1 
ATOM   11856 C  CZ  . ARG D 3 216 ? 147.134 152.950 113.948 1.00 37.34  ? 112 ARG D CZ  1 
ATOM   11857 N  NH1 . ARG D 3 216 ? 147.967 153.954 113.716 1.00 37.34  ? 112 ARG D NH1 1 
ATOM   11858 N  NH2 . ARG D 3 216 ? 146.212 153.063 114.894 1.00 37.34  ? 112 ARG D NH2 1 
ATOM   11859 N  N   . ILE D 3 217 ? 151.263 148.472 108.653 1.00 35.64  ? 113 ILE D N   1 
ATOM   11860 C  CA  . ILE D 3 217 ? 152.105 148.364 107.465 1.00 35.64  ? 113 ILE D CA  1 
ATOM   11861 C  C   . ILE D 3 217 ? 151.620 147.222 106.581 1.00 35.64  ? 113 ILE D C   1 
ATOM   11862 O  O   . ILE D 3 217 ? 151.754 147.264 105.351 1.00 35.64  ? 113 ILE D O   1 
ATOM   11863 C  CB  . ILE D 3 217 ? 153.581 148.188 107.873 1.00 35.64  ? 113 ILE D CB  1 
ATOM   11864 C  CG1 . ILE D 3 217 ? 154.063 149.409 108.657 1.00 35.64  ? 113 ILE D CG1 1 
ATOM   11865 C  CG2 . ILE D 3 217 ? 154.464 147.968 106.654 1.00 35.64  ? 113 ILE D CG2 1 
ATOM   11866 C  CD1 . ILE D 3 217 ? 155.417 149.224 109.307 1.00 35.64  ? 113 ILE D CD1 1 
ATOM   11867 N  N   . GLN D 3 218 ? 151.029 146.193 107.192 1.00 41.02  ? 114 GLN D N   1 
ATOM   11868 C  CA  . GLN D 3 218 ? 150.434 145.110 106.422 1.00 41.02  ? 114 GLN D CA  1 
ATOM   11869 C  C   . GLN D 3 218 ? 149.197 145.561 105.651 1.00 41.02  ? 114 GLN D C   1 
ATOM   11870 O  O   . GLN D 3 218 ? 148.851 144.939 104.641 1.00 41.02  ? 114 GLN D O   1 
ATOM   11871 C  CB  . GLN D 3 218 ? 150.084 143.946 107.353 1.00 41.02  ? 114 GLN D CB  1 
ATOM   11872 C  CG  . GLN D 3 218 ? 149.587 142.695 106.648 1.00 41.02  ? 114 GLN D CG  1 
ATOM   11873 C  CD  . GLN D 3 218 ? 149.313 141.555 107.607 1.00 41.02  ? 114 GLN D CD  1 
ATOM   11874 O  OE1 . GLN D 3 218 ? 149.450 141.702 108.821 1.00 41.02  ? 114 GLN D OE1 1 
ATOM   11875 N  NE2 . GLN D 3 218 ? 148.927 140.406 107.065 1.00 41.02  ? 114 GLN D NE2 1 
ATOM   11876 N  N   . GLN D 3 219 ? 148.537 146.637 106.086 1.00 43.38  ? 115 GLN D N   1 
ATOM   11877 C  CA  . GLN D 3 219 ? 147.310 147.067 105.421 1.00 43.38  ? 115 GLN D CA  1 
ATOM   11878 C  C   . GLN D 3 219 ? 147.608 147.935 104.203 1.00 43.38  ? 115 GLN D C   1 
ATOM   11879 O  O   . GLN D 3 219 ? 146.696 148.505 103.594 1.00 43.38  ? 115 GLN D O   1 
ATOM   11880 C  CB  . GLN D 3 219 ? 146.400 147.800 106.408 1.00 43.38  ? 115 GLN D CB  1 
ATOM   11881 C  CG  . GLN D 3 219 ? 145.802 146.886 107.466 1.00 43.38  ? 115 GLN D CG  1 
ATOM   11882 C  CD  . GLN D 3 219 ? 144.861 147.608 108.409 1.00 43.38  ? 115 GLN D CD  1 
ATOM   11883 O  OE1 . GLN D 3 219 ? 144.695 148.824 108.331 1.00 43.38  ? 115 GLN D OE1 1 
ATOM   11884 N  NE2 . GLN D 3 219 ? 144.234 146.856 109.307 1.00 43.38  ? 115 GLN D NE2 1 
ATOM   11885 N  N   . MET D 3 220 ? 148.884 148.056 103.836 1.00 50.19  ? 116 MET D N   1 
ATOM   11886 C  CA  . MET D 3 220 ? 149.236 148.547 102.510 1.00 50.19  ? 116 MET D CA  1 
ATOM   11887 C  C   . MET D 3 220 ? 150.329 147.717 101.853 1.00 50.19  ? 116 MET D C   1 
ATOM   11888 O  O   . MET D 3 220 ? 150.709 148.010 100.714 1.00 50.19  ? 116 MET D O   1 
ATOM   11889 C  CB  . MET D 3 220 ? 149.658 150.019 102.555 1.00 50.19  ? 116 MET D CB  1 
ATOM   11890 C  CG  . MET D 3 220 ? 150.915 150.316 103.342 1.00 50.19  ? 116 MET D CG  1 
ATOM   11891 S  SD  . MET D 3 220 ? 151.307 152.074 103.258 1.00 50.19  ? 116 MET D SD  1 
ATOM   11892 C  CE  . MET D 3 220 ? 149.984 152.763 104.246 1.00 50.19  ? 116 MET D CE  1 
ATOM   11893 N  N   . LEU D 3 221 ? 150.840 146.699 102.541 1.00 49.80  ? 117 LEU D N   1 
ATOM   11894 C  CA  . LEU D 3 221 ? 151.684 145.667 101.942 1.00 49.80  ? 117 LEU D CA  1 
ATOM   11895 C  C   . LEU D 3 221 ? 151.025 144.318 102.204 1.00 49.80  ? 117 LEU D C   1 
ATOM   11896 O  O   . LEU D 3 221 ? 151.570 143.473 102.925 1.00 49.80  ? 117 LEU D O   1 
ATOM   11897 C  CB  . LEU D 3 221 ? 153.105 145.707 102.508 1.00 49.80  ? 117 LEU D CB  1 
ATOM   11898 C  CG  . LEU D 3 221 ? 154.130 146.678 101.910 1.00 49.80  ? 117 LEU D CG  1 
ATOM   11899 C  CD1 . LEU D 3 221 ? 154.377 146.364 100.443 1.00 49.80  ? 117 LEU D CD1 1 
ATOM   11900 C  CD2 . LEU D 3 221 ? 153.725 148.134 102.096 1.00 49.80  ? 117 LEU D CD2 1 
ATOM   11901 N  N   . PRO D 3 222 ? 149.841 144.081 101.628 1.00 49.87  ? 118 PRO D N   1 
ATOM   11902 C  CA  . PRO D 3 222 ? 149.060 142.897 102.023 1.00 49.87  ? 118 PRO D CA  1 
ATOM   11903 C  C   . PRO D 3 222 ? 149.654 141.583 101.554 1.00 49.87  ? 118 PRO D C   1 
ATOM   11904 O  O   . PRO D 3 222 ? 149.307 140.535 102.112 1.00 49.87  ? 118 PRO D O   1 
ATOM   11905 C  CB  . PRO D 3 222 ? 147.693 143.150 101.376 1.00 49.87  ? 118 PRO D CB  1 
ATOM   11906 C  CG  . PRO D 3 222 ? 148.007 143.976 100.179 1.00 49.87  ? 118 PRO D CG  1 
ATOM   11907 C  CD  . PRO D 3 222 ? 149.168 144.853 100.567 1.00 49.87  ? 118 PRO D CD  1 
ATOM   11908 N  N   . ASP D 3 223 ? 150.531 141.601 100.553 1.00 49.01  ? 119 ASP D N   1 
ATOM   11909 C  CA  . ASP D 3 223 ? 151.123 140.372 100.042 1.00 49.01  ? 119 ASP D CA  1 
ATOM   11910 C  C   . ASP D 3 223 ? 152.153 139.766 100.986 1.00 49.01  ? 119 ASP D C   1 
ATOM   11911 O  O   . ASP D 3 223 ? 152.172 138.541 101.148 1.00 49.01  ? 119 ASP D O   1 
ATOM   11912 C  CB  . ASP D 3 223 ? 151.752 140.632 98.668  1.00 49.01  ? 119 ASP D CB  1 
ATOM   11913 C  CG  . ASP D 3 223 ? 152.816 141.720 98.702  1.00 49.01  ? 119 ASP D CG  1 
ATOM   11914 O  OD1 . ASP D 3 223 ? 153.031 142.325 99.774  1.00 49.01  ? 119 ASP D OD1 1 
ATOM   11915 O  OD2 . ASP D 3 223 ? 153.438 141.973 97.647  1.00 49.01  ? 119 ASP D OD2 1 
ATOM   11916 N  N   . LYS D 3 224 ? 152.995 140.582 101.614 1.00 39.58  ? 120 LYS D N   1 
ATOM   11917 C  CA  . LYS D 3 224 ? 154.027 140.109 102.528 1.00 39.58  ? 120 LYS D CA  1 
ATOM   11918 C  C   . LYS D 3 224 ? 153.426 139.892 103.909 1.00 39.58  ? 120 LYS D C   1 
ATOM   11919 O  O   . LYS D 3 224 ? 152.455 140.560 104.282 1.00 39.58  ? 120 LYS D O   1 
ATOM   11920 C  CB  . LYS D 3 224 ? 155.188 141.102 102.604 1.00 39.58  ? 120 LYS D CB  1 
ATOM   11921 C  CG  . LYS D 3 224 ? 155.896 141.309 101.279 1.00 39.58  ? 120 LYS D CG  1 
ATOM   11922 C  CD  . LYS D 3 224 ? 156.595 140.036 100.826 1.00 39.58  ? 120 LYS D CD  1 
ATOM   11923 C  CE  . LYS D 3 224 ? 157.382 140.260 99.544  1.00 39.58  ? 120 LYS D CE  1 
ATOM   11924 N  NZ  . LYS D 3 224 ? 158.013 139.003 99.057  1.00 39.58  ? 120 LYS D NZ  1 
ATOM   11925 N  N   . SER D 3 225 ? 154.000 138.957 104.660 1.00 27.19  ? 121 SER D N   1 
ATOM   11926 C  CA  . SER D 3 225 ? 153.500 138.664 105.992 1.00 27.19  ? 121 SER D CA  1 
ATOM   11927 C  C   . SER D 3 225 ? 153.976 139.719 106.986 1.00 27.19  ? 121 SER D C   1 
ATOM   11928 O  O   . SER D 3 225 ? 153.785 140.923 106.799 1.00 27.19  ? 121 SER D O   1 
ATOM   11929 C  CB  . SER D 3 225 ? 153.951 137.275 106.444 1.00 27.19  ? 121 SER D CB  1 
ATOM   11930 O  OG  . SER D 3 225 ? 155.356 137.228 106.615 1.00 27.19  ? 121 SER D OG  1 
ATOM   11931 N  N   . ILE D 3 226 ? 154.611 139.246 108.060 1.00 18.05  ? 122 ILE D N   1 
ATOM   11932 C  CA  . ILE D 3 226 ? 155.082 140.157 109.100 1.00 18.05  ? 122 ILE D CA  1 
ATOM   11933 C  C   . ILE D 3 226 ? 156.541 139.878 109.434 1.00 18.05  ? 122 ILE D C   1 
ATOM   11934 O  O   . ILE D 3 226 ? 157.313 140.798 109.730 1.00 18.05  ? 122 ILE D O   1 
ATOM   11935 C  CB  . ILE D 3 226 ? 154.179 140.054 110.344 1.00 18.05  ? 122 ILE D CB  1 
ATOM   11936 C  CG1 . ILE D 3 226 ? 152.756 140.484 109.996 1.00 18.05  ? 122 ILE D CG1 1 
ATOM   11937 C  CG2 . ILE D 3 226 ? 154.711 140.918 111.473 1.00 18.05  ? 122 ILE D CG2 1 
ATOM   11938 C  CD1 . ILE D 3 226 ? 151.748 140.145 111.046 1.00 18.05  ? 122 ILE D CD1 1 
ATOM   11939 N  N   . ALA D 3 227 ? 156.946 138.606 109.380 1.00 19.45  ? 123 ALA D N   1 
ATOM   11940 C  CA  . ALA D 3 227 ? 158.327 138.257 109.697 1.00 19.45  ? 123 ALA D CA  1 
ATOM   11941 C  C   . ALA D 3 227 ? 159.297 138.883 108.705 1.00 19.45  ? 123 ALA D C   1 
ATOM   11942 O  O   . ALA D 3 227 ? 160.435 139.212 109.061 1.00 19.45  ? 123 ALA D O   1 
ATOM   11943 C  CB  . ALA D 3 227 ? 158.491 136.738 109.726 1.00 19.45  ? 123 ALA D CB  1 
ATOM   11944 N  N   . SER D 3 228 ? 158.867 139.062 107.455 1.00 16.17  ? 124 SER D N   1 
ATOM   11945 C  CA  . SER D 3 228 ? 159.740 139.692 106.471 1.00 16.17  ? 124 SER D CA  1 
ATOM   11946 C  C   . SER D 3 228 ? 159.735 141.208 106.625 1.00 16.17  ? 124 SER D C   1 
ATOM   11947 O  O   . SER D 3 228 ? 160.726 141.873 106.301 1.00 16.17  ? 124 SER D O   1 
ATOM   11948 C  CB  . SER D 3 228 ? 159.321 139.287 105.060 1.00 16.17  ? 124 SER D CB  1 
ATOM   11949 O  OG  . SER D 3 228 ? 160.175 139.875 104.095 1.00 16.17  ? 124 SER D OG  1 
ATOM   11950 N  N   . LEU D 3 229 ? 158.629 141.774 107.116 1.00 14.71  ? 125 LEU D N   1 
ATOM   11951 C  CA  . LEU D 3 229 ? 158.612 143.199 107.430 1.00 14.71  ? 125 LEU D CA  1 
ATOM   11952 C  C   . LEU D 3 229 ? 159.551 143.512 108.586 1.00 14.71  ? 125 LEU D C   1 
ATOM   11953 O  O   . LEU D 3 229 ? 160.331 144.470 108.523 1.00 14.71  ? 125 LEU D O   1 
ATOM   11954 C  CB  . LEU D 3 229 ? 157.191 143.654 107.765 1.00 14.71  ? 125 LEU D CB  1 
ATOM   11955 C  CG  . LEU D 3 229 ? 156.141 143.643 106.653 1.00 14.71  ? 125 LEU D CG  1 
ATOM   11956 C  CD1 . LEU D 3 229 ? 154.773 143.996 107.215 1.00 14.71  ? 125 LEU D CD1 1 
ATOM   11957 C  CD2 . LEU D 3 229 ? 156.525 144.600 105.538 1.00 14.71  ? 125 LEU D CD2 1 
ATOM   11958 N  N   . VAL D 3 230 ? 159.489 142.713 109.653 1.00 10.85  ? 126 VAL D N   1 
ATOM   11959 C  CA  . VAL D 3 230 ? 160.361 142.930 110.803 1.00 10.85  ? 126 VAL D CA  1 
ATOM   11960 C  C   . VAL D 3 230 ? 161.808 142.622 110.439 1.00 10.85  ? 126 VAL D C   1 
ATOM   11961 O  O   . VAL D 3 230 ? 162.734 143.314 110.878 1.00 10.85  ? 126 VAL D O   1 
ATOM   11962 C  CB  . VAL D 3 230 ? 159.881 142.088 112.000 1.00 10.85  ? 126 VAL D CB  1 
ATOM   11963 C  CG1 . VAL D 3 230 ? 160.838 142.221 113.165 1.00 10.85  ? 126 VAL D CG1 1 
ATOM   11964 C  CG2 . VAL D 3 230 ? 158.482 142.509 112.414 1.00 10.85  ? 126 VAL D CG2 1 
ATOM   11965 N  N   . LYS D 3 231 ? 162.027 141.587 109.625 1.00 11.86  ? 127 LYS D N   1 
ATOM   11966 C  CA  . LYS D 3 231 ? 163.386 141.266 109.202 1.00 11.86  ? 127 LYS D CA  1 
ATOM   11967 C  C   . LYS D 3 231 ? 163.961 142.365 108.319 1.00 11.86  ? 127 LYS D C   1 
ATOM   11968 O  O   . LYS D 3 231 ? 165.166 142.641 108.361 1.00 11.86  ? 127 LYS D O   1 
ATOM   11969 C  CB  . LYS D 3 231 ? 163.412 139.926 108.469 1.00 11.86  ? 127 LYS D CB  1 
ATOM   11970 C  CG  . LYS D 3 231 ? 164.811 139.458 108.115 1.00 11.86  ? 127 LYS D CG  1 
ATOM   11971 C  CD  . LYS D 3 231 ? 164.795 138.085 107.474 1.00 11.86  ? 127 LYS D CD  1 
ATOM   11972 C  CE  . LYS D 3 231 ? 166.202 137.630 107.129 1.00 11.86  ? 127 LYS D CE  1 
ATOM   11973 N  NZ  . LYS D 3 231 ? 166.205 136.279 106.505 1.00 11.86  ? 127 LYS D NZ  1 
ATOM   11974 N  N   . PHE D 3 232 ? 163.113 143.006 107.512 1.00 20.86  ? 128 PHE D N   1 
ATOM   11975 C  CA  . PHE D 3 232 ? 163.581 144.097 106.664 1.00 20.86  ? 128 PHE D CA  1 
ATOM   11976 C  C   . PHE D 3 232 ? 163.784 145.377 107.464 1.00 20.86  ? 128 PHE D C   1 
ATOM   11977 O  O   . PHE D 3 232 ? 164.633 146.205 107.114 1.00 20.86  ? 128 PHE D O   1 
ATOM   11978 C  CB  . PHE D 3 232 ? 162.594 144.330 105.521 1.00 20.86  ? 128 PHE D CB  1 
ATOM   11979 C  CG  . PHE D 3 232 ? 162.974 145.463 104.614 1.00 20.86  ? 128 PHE D CG  1 
ATOM   11980 C  CD1 . PHE D 3 232 ? 163.998 145.319 103.695 1.00 20.86  ? 128 PHE D CD1 1 
ATOM   11981 C  CD2 . PHE D 3 232 ? 162.305 146.674 104.682 1.00 20.86  ? 128 PHE D CD2 1 
ATOM   11982 C  CE1 . PHE D 3 232 ? 164.349 146.362 102.862 1.00 20.86  ? 128 PHE D CE1 1 
ATOM   11983 C  CE2 . PHE D 3 232 ? 162.652 147.720 103.851 1.00 20.86  ? 128 PHE D CE2 1 
ATOM   11984 C  CZ  . PHE D 3 232 ? 163.674 147.564 102.941 1.00 20.86  ? 128 PHE D CZ  1 
ATOM   11985 N  N   . TYR D 3 233 ? 163.015 145.559 108.541 1.00 16.67  ? 129 TYR D N   1 
ATOM   11986 C  CA  . TYR D 3 233 ? 163.109 146.796 109.309 1.00 16.67  ? 129 TYR D CA  1 
ATOM   11987 C  C   . TYR D 3 233 ? 164.434 146.892 110.056 1.00 16.67  ? 129 TYR D C   1 
ATOM   11988 O  O   . TYR D 3 233 ? 165.138 147.903 109.951 1.00 16.67  ? 129 TYR D O   1 
ATOM   11989 C  CB  . TYR D 3 233 ? 161.936 146.908 110.279 1.00 16.67  ? 129 TYR D CB  1 
ATOM   11990 C  CG  . TYR D 3 233 ? 161.991 148.156 111.123 1.00 16.67  ? 129 TYR D CG  1 
ATOM   11991 C  CD1 . TYR D 3 233 ? 161.737 149.401 110.568 1.00 16.67  ? 129 TYR D CD1 1 
ATOM   11992 C  CD2 . TYR D 3 233 ? 162.295 148.092 112.475 1.00 16.67  ? 129 TYR D CD2 1 
ATOM   11993 C  CE1 . TYR D 3 233 ? 161.790 150.546 111.333 1.00 16.67  ? 129 TYR D CE1 1 
ATOM   11994 C  CE2 . TYR D 3 233 ? 162.347 149.232 113.249 1.00 16.67  ? 129 TYR D CE2 1 
ATOM   11995 C  CZ  . TYR D 3 233 ? 162.094 150.456 112.673 1.00 16.67  ? 129 TYR D CZ  1 
ATOM   11996 O  OH  . TYR D 3 233 ? 162.146 151.596 113.438 1.00 16.67  ? 129 TYR D OH  1 
ATOM   11997 N  N   . TYR D 3 234 ? 164.786 145.855 110.822 1.00 12.16  ? 130 TYR D N   1 
ATOM   11998 C  CA  . TYR D 3 234 ? 166.076 145.852 111.506 1.00 12.16  ? 130 TYR D CA  1 
ATOM   11999 C  C   . TYR D 3 234 ? 167.235 145.940 110.524 1.00 12.16  ? 130 TYR D C   1 
ATOM   12000 O  O   . TYR D 3 234 ? 168.278 146.518 110.851 1.00 12.16  ? 130 TYR D O   1 
ATOM   12001 C  CB  . TYR D 3 234 ? 166.217 144.606 112.378 1.00 12.16  ? 130 TYR D CB  1 
ATOM   12002 C  CG  . TYR D 3 234 ? 165.372 144.633 113.631 1.00 12.16  ? 130 TYR D CG  1 
ATOM   12003 C  CD1 . TYR D 3 234 ? 165.794 145.327 114.760 1.00 12.16  ? 130 TYR D CD1 1 
ATOM   12004 C  CD2 . TYR D 3 234 ? 164.156 143.966 113.688 1.00 12.16  ? 130 TYR D CD2 1 
ATOM   12005 C  CE1 . TYR D 3 234 ? 165.031 145.353 115.907 1.00 12.16  ? 130 TYR D CE1 1 
ATOM   12006 C  CE2 . TYR D 3 234 ? 163.387 143.990 114.833 1.00 12.16  ? 130 TYR D CE2 1 
ATOM   12007 C  CZ  . TYR D 3 234 ? 163.830 144.683 115.936 1.00 12.16  ? 130 TYR D CZ  1 
ATOM   12008 O  OH  . TYR D 3 234 ? 163.064 144.702 117.071 1.00 12.16  ? 130 TYR D OH  1 
ATOM   12009 N  N   . SER D 3 235 ? 167.076 145.382 109.324 1.00 15.40  ? 131 SER D N   1 
ATOM   12010 C  CA  . SER D 3 235 ? 168.077 145.572 108.282 1.00 15.40  ? 131 SER D CA  1 
ATOM   12011 C  C   . SER D 3 235 ? 167.783 146.806 107.440 1.00 15.40  ? 131 SER D C   1 
ATOM   12012 O  O   . SER D 3 235 ? 168.307 146.933 106.328 1.00 15.40  ? 131 SER D O   1 
ATOM   12013 C  CB  . SER D 3 235 ? 168.155 144.331 107.392 1.00 15.40  ? 131 SER D CB  1 
ATOM   12014 O  OG  . SER D 3 235 ? 169.116 144.498 106.363 1.00 15.40  ? 131 SER D OG  1 
ATOM   12015 N  N   . TRP D 3 236 ? 166.953 147.719 107.949 1.00 24.26  ? 132 TRP D N   1 
ATOM   12016 C  CA  . TRP D 3 236 ? 166.608 148.916 107.191 1.00 24.26  ? 132 TRP D CA  1 
ATOM   12017 C  C   . TRP D 3 236 ? 166.878 150.186 107.988 1.00 24.26  ? 132 TRP D C   1 
ATOM   12018 O  O   . TRP D 3 236 ? 167.016 151.265 107.402 1.00 24.26  ? 132 TRP D O   1 
ATOM   12019 C  CB  . TRP D 3 236 ? 165.141 148.867 106.767 1.00 24.26  ? 132 TRP D CB  1 
ATOM   12020 C  CG  . TRP D 3 236 ? 164.716 150.059 105.977 1.00 24.26  ? 132 TRP D CG  1 
ATOM   12021 C  CD1 . TRP D 3 236 ? 165.112 150.392 104.717 1.00 24.26  ? 132 TRP D CD1 1 
ATOM   12022 C  CD2 . TRP D 3 236 ? 163.834 151.102 106.409 1.00 24.26  ? 132 TRP D CD2 1 
ATOM   12023 N  NE1 . TRP D 3 236 ? 164.518 151.568 104.329 1.00 24.26  ? 132 TRP D NE1 1 
ATOM   12024 C  CE2 . TRP D 3 236 ? 163.730 152.025 105.352 1.00 24.26  ? 132 TRP D CE2 1 
ATOM   12025 C  CE3 . TRP D 3 236 ? 163.118 151.340 107.586 1.00 24.26  ? 132 TRP D CE3 1 
ATOM   12026 C  CZ2 . TRP D 3 236 ? 162.939 153.168 105.435 1.00 24.26  ? 132 TRP D CZ2 1 
ATOM   12027 C  CZ3 . TRP D 3 236 ? 162.333 152.473 107.666 1.00 24.26  ? 132 TRP D CZ3 1 
ATOM   12028 C  CH2 . TRP D 3 236 ? 162.249 153.373 106.597 1.00 24.26  ? 132 TRP D CH2 1 
ATOM   12029 N  N   . LYS D 3 237 ? 166.964 150.080 109.317 1.00 16.42  ? 133 LYS D N   1 
ATOM   12030 C  CA  . LYS D 3 237 ? 167.221 151.236 110.170 1.00 16.42  ? 133 LYS D CA  1 
ATOM   12031 C  C   . LYS D 3 237 ? 168.591 151.859 109.942 1.00 16.42  ? 133 LYS D C   1 
ATOM   12032 O  O   . LYS D 3 237 ? 168.932 152.826 110.632 1.00 16.42  ? 133 LYS D O   1 
ATOM   12033 C  CB  . LYS D 3 237 ? 167.101 150.839 111.640 1.00 16.42  ? 133 LYS D CB  1 
ATOM   12034 C  CG  . LYS D 3 237 ? 165.697 150.529 112.109 1.00 16.42  ? 133 LYS D CG  1 
ATOM   12035 C  CD  . LYS D 3 237 ? 165.739 149.998 113.527 1.00 16.42  ? 133 LYS D CD  1 
ATOM   12036 C  CE  . LYS D 3 237 ? 166.176 151.082 114.493 1.00 16.42  ? 133 LYS D CE  1 
ATOM   12037 N  NZ  . LYS D 3 237 ? 166.146 150.609 115.902 1.00 16.42  ? 133 LYS D NZ  1 
ATOM   12038 N  N   . LYS D 3 238 ? 169.379 151.334 109.003 1.00 25.58  ? 134 LYS D N   1 
ATOM   12039 C  CA  . LYS D 3 238 ? 170.752 151.798 108.836 1.00 25.58  ? 134 LYS D CA  1 
ATOM   12040 C  C   . LYS D 3 238 ? 170.800 153.200 108.242 1.00 25.58  ? 134 LYS D C   1 
ATOM   12041 O  O   . LYS D 3 238 ? 171.784 153.926 108.428 1.00 25.58  ? 134 LYS D O   1 
ATOM   12042 C  CB  . LYS D 3 238 ? 171.521 150.812 107.959 1.00 25.58  ? 134 LYS D CB  1 
ATOM   12043 C  CG  . LYS D 3 238 ? 171.680 149.440 108.589 1.00 25.58  ? 134 LYS D CG  1 
ATOM   12044 C  CD  . LYS D 3 238 ? 172.440 148.493 107.679 1.00 25.58  ? 134 LYS D CD  1 
ATOM   12045 C  CE  . LYS D 3 238 ? 172.561 147.113 108.304 1.00 25.58  ? 134 LYS D CE  1 
ATOM   12046 N  NZ  . LYS D 3 238 ? 173.298 146.163 107.426 1.00 25.58  ? 134 LYS D NZ  1 
ATOM   12047 N  N   . THR D 3 239 ? 169.753 153.599 107.526 1.00 28.69  ? 135 THR D N   1 
ATOM   12048 C  CA  . THR D 3 239 ? 169.704 154.922 106.911 1.00 28.69  ? 135 THR D CA  1 
ATOM   12049 C  C   . THR D 3 239 ? 169.602 156.017 107.967 1.00 28.69  ? 135 THR D C   1 
ATOM   12050 O  O   . THR D 3 239 ? 168.509 156.489 108.280 1.00 28.69  ? 135 THR D O   1 
ATOM   12051 C  CB  . THR D 3 239 ? 168.517 155.053 105.939 1.00 28.69  ? 135 THR D CB  1 
ATOM   12052 O  OG1 . THR D 3 239 ? 167.287 154.895 106.658 1.00 28.69  ? 135 THR D OG1 1 
ATOM   12053 C  CG2 . THR D 3 239 ? 168.600 153.995 104.851 1.00 28.69  ? 135 THR D CG2 1 
HETATM 12054 ZN ZN  . ZN  E 4 .   ? 166.913 140.328 134.203 1.00 29.04  ? 600 ZN  C ZN  1 
HETATM 12055 C  C1  . IHP F 5 .   ? 165.925 153.630 120.940 1.00 14.37  ? 701 IHP D C1  1 
HETATM 12056 C  C2  . IHP F 5 .   ? 166.835 152.806 120.044 1.00 14.37  ? 701 IHP D C2  1 
HETATM 12057 C  C3  . IHP F 5 .   ? 166.336 151.375 119.931 1.00 14.37  ? 701 IHP D C3  1 
HETATM 12058 C  C4  . IHP F 5 .   ? 164.909 151.370 119.410 1.00 14.37  ? 701 IHP D C4  1 
HETATM 12059 C  C5  . IHP F 5 .   ? 164.020 152.124 120.382 1.00 14.37  ? 701 IHP D C5  1 
HETATM 12060 C  C6  . IHP F 5 .   ? 164.486 153.567 120.455 1.00 14.37  ? 701 IHP D C6  1 
HETATM 12061 O  O11 . IHP F 5 .   ? 166.363 155.004 120.900 1.00 14.37  ? 701 IHP D O11 1 
HETATM 12062 P  P1  . IHP F 5 .   ? 167.102 155.851 122.074 1.00 14.37  ? 701 IHP D P1  1 
HETATM 12063 O  O21 . IHP F 5 .   ? 167.062 157.297 121.632 1.00 14.37  ? 701 IHP D O21 1 
HETATM 12064 O  O31 . IHP F 5 .   ? 166.298 155.594 123.331 1.00 14.37  ? 701 IHP D O31 1 
HETATM 12065 O  O41 . IHP F 5 .   ? 168.508 155.294 122.154 1.00 14.37  ? 701 IHP D O41 1 
HETATM 12066 O  O12 . IHP F 5 .   ? 166.860 153.399 118.728 1.00 14.37  ? 701 IHP D O12 1 
HETATM 12067 P  P2  . IHP F 5 .   ? 168.121 153.858 117.809 1.00 14.37  ? 701 IHP D P2  1 
HETATM 12068 O  O22 . IHP F 5 .   ? 167.828 155.284 117.400 1.00 14.37  ? 701 IHP D O22 1 
HETATM 12069 O  O32 . IHP F 5 .   ? 169.345 153.737 118.694 1.00 14.37  ? 701 IHP D O32 1 
HETATM 12070 O  O42 . IHP F 5 .   ? 168.151 152.901 116.635 1.00 14.37  ? 701 IHP D O42 1 
HETATM 12071 O  O13 . IHP F 5 .   ? 167.177 150.660 119.002 1.00 14.37  ? 701 IHP D O13 1 
HETATM 12072 P  P3  . IHP F 5 .   ? 168.112 149.364 119.298 1.00 14.37  ? 701 IHP D P3  1 
HETATM 12073 O  O23 . IHP F 5 .   ? 167.156 148.204 119.452 1.00 14.37  ? 701 IHP D O23 1 
HETATM 12074 O  O33 . IHP F 5 .   ? 168.869 149.678 120.572 1.00 14.37  ? 701 IHP D O33 1 
HETATM 12075 O  O43 . IHP F 5 .   ? 169.024 149.222 118.098 1.00 14.37  ? 701 IHP D O43 1 
HETATM 12076 O  O14 . IHP F 5 .   ? 164.446 150.010 119.285 1.00 14.37  ? 701 IHP D O14 1 
HETATM 12077 P  P4  . IHP F 5 .   ? 163.922 149.268 117.936 1.00 14.37  ? 701 IHP D P4  1 
HETATM 12078 O  O24 . IHP F 5 .   ? 162.489 148.871 118.206 1.00 14.37  ? 701 IHP D O24 1 
HETATM 12079 O  O34 . IHP F 5 .   ? 164.050 150.298 116.834 1.00 14.37  ? 701 IHP D O34 1 
HETATM 12080 O  O44 . IHP F 5 .   ? 164.838 148.080 117.733 1.00 14.37  ? 701 IHP D O44 1 
HETATM 12081 O  O15 . IHP F 5 .   ? 162.658 152.090 119.906 1.00 14.37  ? 701 IHP D O15 1 
HETATM 12082 P  P5  . IHP F 5 .   ? 161.321 151.731 120.759 1.00 14.37  ? 701 IHP D P5  1 
HETATM 12083 O  O25 . IHP F 5 .   ? 161.286 152.719 121.903 1.00 14.37  ? 701 IHP D O25 1 
HETATM 12084 O  O35 . IHP F 5 .   ? 161.497 150.299 121.220 1.00 14.37  ? 701 IHP D O35 1 
HETATM 12085 O  O45 . IHP F 5 .   ? 160.161 151.897 119.799 1.00 14.37  ? 701 IHP D O45 1 
HETATM 12086 O  O16 . IHP F 5 .   ? 163.646 154.284 121.384 1.00 14.37  ? 701 IHP D O16 1 
HETATM 12087 P  P6  . IHP F 5 .   ? 162.877 155.702 121.176 1.00 14.37  ? 701 IHP D P6  1 
HETATM 12088 O  O26 . IHP F 5 .   ? 162.841 156.353 122.540 1.00 14.37  ? 701 IHP D O26 1 
HETATM 12089 O  O36 . IHP F 5 .   ? 161.500 155.353 120.651 1.00 14.37  ? 701 IHP D O36 1 
HETATM 12090 O  O46 . IHP F 5 .   ? 163.706 156.478 120.173 1.00 14.37  ? 701 IHP D O46 1 
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