data_8VA6
# 
_entry.id   8VA6 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.399 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8VA6         pdb_00008va6 10.2210/pdb8va6/pdb 
WWPDB D_1000279368 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2024-11-20 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8VA6 
_pdbx_database_status.recvd_initial_deposition_date   2023-12-11 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
loop_
_pdbx_contact_author.id 
_pdbx_contact_author.email 
_pdbx_contact_author.name_first 
_pdbx_contact_author.name_last 
_pdbx_contact_author.name_mi 
_pdbx_contact_author.role 
_pdbx_contact_author.identifier_ORCID 
4 tomaszc@umich.edu  Tomasz  Cierpicki ? 'principal investigator/group leader' 0000-0003-2058-0658 
5 jolantag@umich.edu Jolanta Grembecka ? 'principal investigator/group leader' 0000-0002-6180-9095 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Clegg, B.D.'    1 0000-0001-6651-3878 
'Linhares, B.M.' 2 0000-0002-0906-6191 
'Cierpicki, T.'  3 0000-0003-2058-0658 
'Grembecka, J.'  4 0000-0002-6180-9095 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'Menin in complex with Ziftomenib (KO-539)' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Clegg, B.D.'    1 0000-0001-6651-3878 
primary 'Linhares, B.M.' 2 0000-0002-0906-6191 
primary 'Cierpicki, T.'  3 0000-0003-2058-0658 
primary 'Grembecka, J.'  4 0000-0002-6180-9095 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man Menin                   54600.246 1   ? ? ? ? 
2 non-polymer syn Ziftomenib              717.871   1   ? ? ? ? 
3 non-polymer syn 'DI(HYDROXYETHYL)ETHER' 106.120   2   ? ? ? ? 
4 non-polymer syn 'SULFATE ION'           96.063    3   ? ? ? ? 
5 non-polymer syn 'DIMETHYL SULFOXIDE'    78.133    2   ? ? ? ? 
6 non-polymer syn 'TETRAETHYLENE GLYCOL'  194.226   2   ? ? ? ? 
7 non-polymer syn 1,2-ETHANEDIOL          62.068    1   ? ? ? ? 
8 water       nat water                   18.015    370 ? ? ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;GGSSSMGLKAAQKTLFPLRSIDDVVRLFAAELGREEPDLVLLSLVLGFVEHFLAVNRVGLTYFPVADLSIIAALYARFTA
QIRGAVDLSLYPREGGVSSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFITGTKLDSSGVAFAVVGACQALGLRDVHL
ALSEDHAWVVFGPNGEQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLKGSYMRCDRKMEVAFMVCAINPSIDLHTDSLE
LLQLQQKLLWLLYDLGHLERYPMALGNLADLEELEPTPGRPDPLTLYHKGIASAKTYYRDEHIYPYMYLAGYHCRNRNVR
EALQAWADTATVIQDYNYCREDEEIYKEFFEVANDVIPNLLKEAASLLEAGSQGSALQDPECFAHLLRFYDGICKWEEGS
PTPVLHVGWATFLVQSLGRFEGQVRQKVRIVSVPAPTASPPPEGPVLTFQSEKMKGMKELLVATKINSSAIKLQLTAQSQ
VQMKKQKVS
;
_entity_poly.pdbx_seq_one_letter_code_can   
;GGSSSMGLKAAQKTLFPLRSIDDVVRLFAAELGREEPDLVLLSLVLGFVEHFLAVNRVGLTYFPVADLSIIAALYARFTA
QIRGAVDLSLYPREGGVSSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFITGTKLDSSGVAFAVVGACQALGLRDVHL
ALSEDHAWVVFGPNGEQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLKGSYMRCDRKMEVAFMVCAINPSIDLHTDSLE
LLQLQQKLLWLLYDLGHLERYPMALGNLADLEELEPTPGRPDPLTLYHKGIASAKTYYRDEHIYPYMYLAGYHCRNRNVR
EALQAWADTATVIQDYNYCREDEEIYKEFFEVANDVIPNLLKEAASLLEAGSQGSALQDPECFAHLLRFYDGICKWEEGS
PTPVLHVGWATFLVQSLGRFEGQVRQKVRIVSVPAPTASPPPEGPVLTFQSEKMKGMKELLVATKINSSAIKLQLTAQSQ
VQMKKQKVS
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 Ziftomenib              K5O 
3 'DI(HYDROXYETHYL)ETHER' PEG 
4 'SULFATE ION'           SO4 
5 'DIMETHYL SULFOXIDE'    DMS 
6 'TETRAETHYLENE GLYCOL'  PG4 
7 1,2-ETHANEDIOL          EDO 
8 water                   HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   GLY n 
1 2   GLY n 
1 3   SER n 
1 4   SER n 
1 5   SER n 
1 6   MET n 
1 7   GLY n 
1 8   LEU n 
1 9   LYS n 
1 10  ALA n 
1 11  ALA n 
1 12  GLN n 
1 13  LYS n 
1 14  THR n 
1 15  LEU n 
1 16  PHE n 
1 17  PRO n 
1 18  LEU n 
1 19  ARG n 
1 20  SER n 
1 21  ILE n 
1 22  ASP n 
1 23  ASP n 
1 24  VAL n 
1 25  VAL n 
1 26  ARG n 
1 27  LEU n 
1 28  PHE n 
1 29  ALA n 
1 30  ALA n 
1 31  GLU n 
1 32  LEU n 
1 33  GLY n 
1 34  ARG n 
1 35  GLU n 
1 36  GLU n 
1 37  PRO n 
1 38  ASP n 
1 39  LEU n 
1 40  VAL n 
1 41  LEU n 
1 42  LEU n 
1 43  SER n 
1 44  LEU n 
1 45  VAL n 
1 46  LEU n 
1 47  GLY n 
1 48  PHE n 
1 49  VAL n 
1 50  GLU n 
1 51  HIS n 
1 52  PHE n 
1 53  LEU n 
1 54  ALA n 
1 55  VAL n 
1 56  ASN n 
1 57  ARG n 
1 58  VAL n 
1 59  GLY n 
1 60  LEU n 
1 61  THR n 
1 62  TYR n 
1 63  PHE n 
1 64  PRO n 
1 65  VAL n 
1 66  ALA n 
1 67  ASP n 
1 68  LEU n 
1 69  SER n 
1 70  ILE n 
1 71  ILE n 
1 72  ALA n 
1 73  ALA n 
1 74  LEU n 
1 75  TYR n 
1 76  ALA n 
1 77  ARG n 
1 78  PHE n 
1 79  THR n 
1 80  ALA n 
1 81  GLN n 
1 82  ILE n 
1 83  ARG n 
1 84  GLY n 
1 85  ALA n 
1 86  VAL n 
1 87  ASP n 
1 88  LEU n 
1 89  SER n 
1 90  LEU n 
1 91  TYR n 
1 92  PRO n 
1 93  ARG n 
1 94  GLU n 
1 95  GLY n 
1 96  GLY n 
1 97  VAL n 
1 98  SER n 
1 99  SER n 
1 100 ARG n 
1 101 GLU n 
1 102 LEU n 
1 103 VAL n 
1 104 LYS n 
1 105 LYS n 
1 106 VAL n 
1 107 SER n 
1 108 ASP n 
1 109 VAL n 
1 110 ILE n 
1 111 TRP n 
1 112 ASN n 
1 113 SER n 
1 114 LEU n 
1 115 SER n 
1 116 ARG n 
1 117 SER n 
1 118 TYR n 
1 119 PHE n 
1 120 LYS n 
1 121 ASP n 
1 122 ARG n 
1 123 ALA n 
1 124 HIS n 
1 125 ILE n 
1 126 GLN n 
1 127 SER n 
1 128 LEU n 
1 129 PHE n 
1 130 SER n 
1 131 PHE n 
1 132 ILE n 
1 133 THR n 
1 134 GLY n 
1 135 THR n 
1 136 LYS n 
1 137 LEU n 
1 138 ASP n 
1 139 SER n 
1 140 SER n 
1 141 GLY n 
1 142 VAL n 
1 143 ALA n 
1 144 PHE n 
1 145 ALA n 
1 146 VAL n 
1 147 VAL n 
1 148 GLY n 
1 149 ALA n 
1 150 CYS n 
1 151 GLN n 
1 152 ALA n 
1 153 LEU n 
1 154 GLY n 
1 155 LEU n 
1 156 ARG n 
1 157 ASP n 
1 158 VAL n 
1 159 HIS n 
1 160 LEU n 
1 161 ALA n 
1 162 LEU n 
1 163 SER n 
1 164 GLU n 
1 165 ASP n 
1 166 HIS n 
1 167 ALA n 
1 168 TRP n 
1 169 VAL n 
1 170 VAL n 
1 171 PHE n 
1 172 GLY n 
1 173 PRO n 
1 174 ASN n 
1 175 GLY n 
1 176 GLU n 
1 177 GLN n 
1 178 THR n 
1 179 ALA n 
1 180 GLU n 
1 181 VAL n 
1 182 THR n 
1 183 TRP n 
1 184 HIS n 
1 185 GLY n 
1 186 LYS n 
1 187 GLY n 
1 188 ASN n 
1 189 GLU n 
1 190 ASP n 
1 191 ARG n 
1 192 ARG n 
1 193 GLY n 
1 194 GLN n 
1 195 THR n 
1 196 VAL n 
1 197 ASN n 
1 198 ALA n 
1 199 GLY n 
1 200 VAL n 
1 201 ALA n 
1 202 GLU n 
1 203 ARG n 
1 204 SER n 
1 205 TRP n 
1 206 LEU n 
1 207 TYR n 
1 208 LEU n 
1 209 LYS n 
1 210 GLY n 
1 211 SER n 
1 212 TYR n 
1 213 MET n 
1 214 ARG n 
1 215 CYS n 
1 216 ASP n 
1 217 ARG n 
1 218 LYS n 
1 219 MET n 
1 220 GLU n 
1 221 VAL n 
1 222 ALA n 
1 223 PHE n 
1 224 MET n 
1 225 VAL n 
1 226 CYS n 
1 227 ALA n 
1 228 ILE n 
1 229 ASN n 
1 230 PRO n 
1 231 SER n 
1 232 ILE n 
1 233 ASP n 
1 234 LEU n 
1 235 HIS n 
1 236 THR n 
1 237 ASP n 
1 238 SER n 
1 239 LEU n 
1 240 GLU n 
1 241 LEU n 
1 242 LEU n 
1 243 GLN n 
1 244 LEU n 
1 245 GLN n 
1 246 GLN n 
1 247 LYS n 
1 248 LEU n 
1 249 LEU n 
1 250 TRP n 
1 251 LEU n 
1 252 LEU n 
1 253 TYR n 
1 254 ASP n 
1 255 LEU n 
1 256 GLY n 
1 257 HIS n 
1 258 LEU n 
1 259 GLU n 
1 260 ARG n 
1 261 TYR n 
1 262 PRO n 
1 263 MET n 
1 264 ALA n 
1 265 LEU n 
1 266 GLY n 
1 267 ASN n 
1 268 LEU n 
1 269 ALA n 
1 270 ASP n 
1 271 LEU n 
1 272 GLU n 
1 273 GLU n 
1 274 LEU n 
1 275 GLU n 
1 276 PRO n 
1 277 THR n 
1 278 PRO n 
1 279 GLY n 
1 280 ARG n 
1 281 PRO n 
1 282 ASP n 
1 283 PRO n 
1 284 LEU n 
1 285 THR n 
1 286 LEU n 
1 287 TYR n 
1 288 HIS n 
1 289 LYS n 
1 290 GLY n 
1 291 ILE n 
1 292 ALA n 
1 293 SER n 
1 294 ALA n 
1 295 LYS n 
1 296 THR n 
1 297 TYR n 
1 298 TYR n 
1 299 ARG n 
1 300 ASP n 
1 301 GLU n 
1 302 HIS n 
1 303 ILE n 
1 304 TYR n 
1 305 PRO n 
1 306 TYR n 
1 307 MET n 
1 308 TYR n 
1 309 LEU n 
1 310 ALA n 
1 311 GLY n 
1 312 TYR n 
1 313 HIS n 
1 314 CYS n 
1 315 ARG n 
1 316 ASN n 
1 317 ARG n 
1 318 ASN n 
1 319 VAL n 
1 320 ARG n 
1 321 GLU n 
1 322 ALA n 
1 323 LEU n 
1 324 GLN n 
1 325 ALA n 
1 326 TRP n 
1 327 ALA n 
1 328 ASP n 
1 329 THR n 
1 330 ALA n 
1 331 THR n 
1 332 VAL n 
1 333 ILE n 
1 334 GLN n 
1 335 ASP n 
1 336 TYR n 
1 337 ASN n 
1 338 TYR n 
1 339 CYS n 
1 340 ARG n 
1 341 GLU n 
1 342 ASP n 
1 343 GLU n 
1 344 GLU n 
1 345 ILE n 
1 346 TYR n 
1 347 LYS n 
1 348 GLU n 
1 349 PHE n 
1 350 PHE n 
1 351 GLU n 
1 352 VAL n 
1 353 ALA n 
1 354 ASN n 
1 355 ASP n 
1 356 VAL n 
1 357 ILE n 
1 358 PRO n 
1 359 ASN n 
1 360 LEU n 
1 361 LEU n 
1 362 LYS n 
1 363 GLU n 
1 364 ALA n 
1 365 ALA n 
1 366 SER n 
1 367 LEU n 
1 368 LEU n 
1 369 GLU n 
1 370 ALA n 
1 371 GLY n 
1 372 SER n 
1 373 GLN n 
1 374 GLY n 
1 375 SER n 
1 376 ALA n 
1 377 LEU n 
1 378 GLN n 
1 379 ASP n 
1 380 PRO n 
1 381 GLU n 
1 382 CYS n 
1 383 PHE n 
1 384 ALA n 
1 385 HIS n 
1 386 LEU n 
1 387 LEU n 
1 388 ARG n 
1 389 PHE n 
1 390 TYR n 
1 391 ASP n 
1 392 GLY n 
1 393 ILE n 
1 394 CYS n 
1 395 LYS n 
1 396 TRP n 
1 397 GLU n 
1 398 GLU n 
1 399 GLY n 
1 400 SER n 
1 401 PRO n 
1 402 THR n 
1 403 PRO n 
1 404 VAL n 
1 405 LEU n 
1 406 HIS n 
1 407 VAL n 
1 408 GLY n 
1 409 TRP n 
1 410 ALA n 
1 411 THR n 
1 412 PHE n 
1 413 LEU n 
1 414 VAL n 
1 415 GLN n 
1 416 SER n 
1 417 LEU n 
1 418 GLY n 
1 419 ARG n 
1 420 PHE n 
1 421 GLU n 
1 422 GLY n 
1 423 GLN n 
1 424 VAL n 
1 425 ARG n 
1 426 GLN n 
1 427 LYS n 
1 428 VAL n 
1 429 ARG n 
1 430 ILE n 
1 431 VAL n 
1 432 SER n 
1 433 VAL n 
1 434 PRO n 
1 435 ALA n 
1 436 PRO n 
1 437 THR n 
1 438 ALA n 
1 439 SER n 
1 440 PRO n 
1 441 PRO n 
1 442 PRO n 
1 443 GLU n 
1 444 GLY n 
1 445 PRO n 
1 446 VAL n 
1 447 LEU n 
1 448 THR n 
1 449 PHE n 
1 450 GLN n 
1 451 SER n 
1 452 GLU n 
1 453 LYS n 
1 454 MET n 
1 455 LYS n 
1 456 GLY n 
1 457 MET n 
1 458 LYS n 
1 459 GLU n 
1 460 LEU n 
1 461 LEU n 
1 462 VAL n 
1 463 ALA n 
1 464 THR n 
1 465 LYS n 
1 466 ILE n 
1 467 ASN n 
1 468 SER n 
1 469 SER n 
1 470 ALA n 
1 471 ILE n 
1 472 LYS n 
1 473 LEU n 
1 474 GLN n 
1 475 LEU n 
1 476 THR n 
1 477 ALA n 
1 478 GLN n 
1 479 SER n 
1 480 GLN n 
1 481 VAL n 
1 482 GLN n 
1 483 MET n 
1 484 LYS n 
1 485 LYS n 
1 486 GLN n 
1 487 LYS n 
1 488 VAL n 
1 489 SER n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1   432 human ? 'MEN1, SCG2' ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 'Escherichia coli' 
562 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
1 2 sample 'Biological sequence' 433 489 human ? 'MEN1, SCG2' ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 'Escherichia coli' 
562 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                 ?                 'C3 H7 N O2'          89.093  
ARG 'L-peptide linking' y ARGININE                ?                 'C6 H15 N4 O2 1'      175.209 
ASN 'L-peptide linking' y ASPARAGINE              ?                 'C4 H8 N2 O3'         132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'         ?                 'C4 H7 N O4'          133.103 
CYS 'L-peptide linking' y CYSTEINE                ?                 'C3 H7 N O2 S'        121.158 
DMS non-polymer         . 'DIMETHYL SULFOXIDE'    ?                 'C2 H6 O S'           78.133  
EDO non-polymer         . 1,2-ETHANEDIOL          'ETHYLENE GLYCOL' 'C2 H6 O2'            62.068  
GLN 'L-peptide linking' y GLUTAMINE               ?                 'C5 H10 N2 O3'        146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'         ?                 'C5 H9 N O4'          147.129 
GLY 'peptide linking'   y GLYCINE                 ?                 'C2 H5 N O2'          75.067  
HIS 'L-peptide linking' y HISTIDINE               ?                 'C6 H10 N3 O2 1'      156.162 
HOH non-polymer         . WATER                   ?                 'H2 O'                18.015  
ILE 'L-peptide linking' y ISOLEUCINE              ?                 'C6 H13 N O2'         131.173 
K5O non-polymer         . Ziftomenib              ?                 'C33 H42 F3 N9 O2 S2' 717.871 
LEU 'L-peptide linking' y LEUCINE                 ?                 'C6 H13 N O2'         131.173 
LYS 'L-peptide linking' y LYSINE                  ?                 'C6 H15 N2 O2 1'      147.195 
MET 'L-peptide linking' y METHIONINE              ?                 'C5 H11 N O2 S'       149.211 
PEG non-polymer         . 'DI(HYDROXYETHYL)ETHER' ?                 'C4 H10 O3'           106.120 
PG4 non-polymer         . 'TETRAETHYLENE GLYCOL'  ?                 'C8 H18 O5'           194.226 
PHE 'L-peptide linking' y PHENYLALANINE           ?                 'C9 H11 N O2'         165.189 
PRO 'L-peptide linking' y PROLINE                 ?                 'C5 H9 N O2'          115.130 
SER 'L-peptide linking' y SERINE                  ?                 'C3 H7 N O3'          105.093 
SO4 non-polymer         . 'SULFATE ION'           ?                 'O4 S -2'             96.063  
THR 'L-peptide linking' y THREONINE               ?                 'C4 H9 N O3'          119.119 
TRP 'L-peptide linking' y TRYPTOPHAN              ?                 'C11 H12 N2 O2'       204.225 
TYR 'L-peptide linking' y TYROSINE                ?                 'C9 H11 N O3'         181.189 
VAL 'L-peptide linking' y VALINE                  ?                 'C5 H11 N O2'         117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   GLY 1   -4  ?   ?   ?   A . n 
A 1 2   GLY 2   -3  ?   ?   ?   A . n 
A 1 3   SER 3   -2  ?   ?   ?   A . n 
A 1 4   SER 4   -1  ?   ?   ?   A . n 
A 1 5   SER 5   0   ?   ?   ?   A . n 
A 1 6   MET 6   1   ?   ?   ?   A . n 
A 1 7   GLY 7   2   2   GLY GLY A . n 
A 1 8   LEU 8   3   3   LEU LEU A . n 
A 1 9   LYS 9   4   4   LYS LYS A . n 
A 1 10  ALA 10  5   5   ALA ALA A . n 
A 1 11  ALA 11  6   6   ALA ALA A . n 
A 1 12  GLN 12  7   7   GLN GLN A . n 
A 1 13  LYS 13  8   8   LYS LYS A . n 
A 1 14  THR 14  9   9   THR THR A . n 
A 1 15  LEU 15  10  10  LEU LEU A . n 
A 1 16  PHE 16  11  11  PHE PHE A . n 
A 1 17  PRO 17  12  12  PRO PRO A . n 
A 1 18  LEU 18  13  13  LEU LEU A . n 
A 1 19  ARG 19  14  14  ARG ARG A . n 
A 1 20  SER 20  15  15  SER SER A . n 
A 1 21  ILE 21  16  16  ILE ILE A . n 
A 1 22  ASP 22  17  17  ASP ASP A . n 
A 1 23  ASP 23  18  18  ASP ASP A . n 
A 1 24  VAL 24  19  19  VAL VAL A . n 
A 1 25  VAL 25  20  20  VAL VAL A . n 
A 1 26  ARG 26  21  21  ARG ARG A . n 
A 1 27  LEU 27  22  22  LEU LEU A . n 
A 1 28  PHE 28  23  23  PHE PHE A . n 
A 1 29  ALA 29  24  24  ALA ALA A . n 
A 1 30  ALA 30  25  25  ALA ALA A . n 
A 1 31  GLU 31  26  26  GLU GLU A . n 
A 1 32  LEU 32  27  27  LEU LEU A . n 
A 1 33  GLY 33  28  28  GLY GLY A . n 
A 1 34  ARG 34  29  29  ARG ARG A . n 
A 1 35  GLU 35  30  30  GLU GLU A . n 
A 1 36  GLU 36  31  31  GLU GLU A . n 
A 1 37  PRO 37  32  32  PRO PRO A . n 
A 1 38  ASP 38  33  33  ASP ASP A . n 
A 1 39  LEU 39  34  34  LEU LEU A . n 
A 1 40  VAL 40  35  35  VAL VAL A . n 
A 1 41  LEU 41  36  36  LEU LEU A . n 
A 1 42  LEU 42  37  37  LEU LEU A . n 
A 1 43  SER 43  38  38  SER SER A . n 
A 1 44  LEU 44  39  39  LEU LEU A . n 
A 1 45  VAL 45  40  40  VAL VAL A . n 
A 1 46  LEU 46  41  41  LEU LEU A . n 
A 1 47  GLY 47  42  42  GLY GLY A . n 
A 1 48  PHE 48  43  43  PHE PHE A . n 
A 1 49  VAL 49  44  44  VAL VAL A . n 
A 1 50  GLU 50  45  45  GLU GLU A . n 
A 1 51  HIS 51  46  46  HIS HIS A . n 
A 1 52  PHE 52  47  47  PHE PHE A . n 
A 1 53  LEU 53  48  48  LEU LEU A . n 
A 1 54  ALA 54  49  49  ALA ALA A . n 
A 1 55  VAL 55  50  50  VAL VAL A . n 
A 1 56  ASN 56  51  51  ASN ASN A . n 
A 1 57  ARG 57  52  52  ARG ARG A . n 
A 1 58  VAL 58  53  53  VAL VAL A . n 
A 1 59  GLY 59  74  74  GLY GLY A . n 
A 1 60  LEU 60  75  75  LEU LEU A . n 
A 1 61  THR 61  76  76  THR THR A . n 
A 1 62  TYR 62  77  77  TYR TYR A . n 
A 1 63  PHE 63  78  78  PHE PHE A . n 
A 1 64  PRO 64  79  79  PRO PRO A . n 
A 1 65  VAL 65  80  80  VAL VAL A . n 
A 1 66  ALA 66  81  81  ALA ALA A . n 
A 1 67  ASP 67  82  82  ASP ASP A . n 
A 1 68  LEU 68  83  83  LEU LEU A . n 
A 1 69  SER 69  84  84  SER SER A . n 
A 1 70  ILE 70  85  85  ILE ILE A . n 
A 1 71  ILE 71  86  86  ILE ILE A . n 
A 1 72  ALA 72  87  87  ALA ALA A . n 
A 1 73  ALA 73  88  88  ALA ALA A . n 
A 1 74  LEU 74  89  89  LEU LEU A . n 
A 1 75  TYR 75  90  90  TYR TYR A . n 
A 1 76  ALA 76  91  91  ALA ALA A . n 
A 1 77  ARG 77  92  92  ARG ARG A . n 
A 1 78  PHE 78  93  93  PHE PHE A . n 
A 1 79  THR 79  94  94  THR THR A . n 
A 1 80  ALA 80  95  95  ALA ALA A . n 
A 1 81  GLN 81  96  96  GLN GLN A . n 
A 1 82  ILE 82  97  97  ILE ILE A . n 
A 1 83  ARG 83  98  98  ARG ARG A . n 
A 1 84  GLY 84  99  99  GLY GLY A . n 
A 1 85  ALA 85  100 100 ALA ALA A . n 
A 1 86  VAL 86  101 101 VAL VAL A . n 
A 1 87  ASP 87  102 102 ASP ASP A . n 
A 1 88  LEU 88  103 103 LEU LEU A . n 
A 1 89  SER 89  104 104 SER SER A . n 
A 1 90  LEU 90  105 105 LEU LEU A . n 
A 1 91  TYR 91  106 106 TYR TYR A . n 
A 1 92  PRO 92  107 107 PRO PRO A . n 
A 1 93  ARG 93  108 108 ARG ARG A . n 
A 1 94  GLU 94  109 109 GLU GLU A . n 
A 1 95  GLY 95  110 110 GLY GLY A . n 
A 1 96  GLY 96  111 111 GLY GLY A . n 
A 1 97  VAL 97  112 112 VAL VAL A . n 
A 1 98  SER 98  113 113 SER SER A . n 
A 1 99  SER 99  114 114 SER SER A . n 
A 1 100 ARG 100 115 115 ARG ARG A . n 
A 1 101 GLU 101 116 116 GLU GLU A . n 
A 1 102 LEU 102 117 117 LEU LEU A . n 
A 1 103 VAL 103 118 118 VAL VAL A . n 
A 1 104 LYS 104 119 119 LYS LYS A . n 
A 1 105 LYS 105 120 120 LYS LYS A . n 
A 1 106 VAL 106 121 121 VAL VAL A . n 
A 1 107 SER 107 122 122 SER SER A . n 
A 1 108 ASP 108 123 123 ASP ASP A . n 
A 1 109 VAL 109 124 124 VAL VAL A . n 
A 1 110 ILE 110 125 125 ILE ILE A . n 
A 1 111 TRP 111 126 126 TRP TRP A . n 
A 1 112 ASN 112 127 127 ASN ASN A . n 
A 1 113 SER 113 128 128 SER SER A . n 
A 1 114 LEU 114 129 129 LEU LEU A . n 
A 1 115 SER 115 130 130 SER SER A . n 
A 1 116 ARG 116 131 131 ARG ARG A . n 
A 1 117 SER 117 132 132 SER SER A . n 
A 1 118 TYR 118 133 133 TYR TYR A . n 
A 1 119 PHE 119 134 134 PHE PHE A . n 
A 1 120 LYS 120 135 135 LYS LYS A . n 
A 1 121 ASP 121 136 136 ASP ASP A . n 
A 1 122 ARG 122 137 137 ARG ARG A . n 
A 1 123 ALA 123 138 138 ALA ALA A . n 
A 1 124 HIS 124 139 139 HIS HIS A . n 
A 1 125 ILE 125 140 140 ILE ILE A . n 
A 1 126 GLN 126 141 141 GLN GLN A . n 
A 1 127 SER 127 142 142 SER SER A . n 
A 1 128 LEU 128 143 143 LEU LEU A . n 
A 1 129 PHE 129 144 144 PHE PHE A . n 
A 1 130 SER 130 145 145 SER SER A . n 
A 1 131 PHE 131 146 146 PHE PHE A . n 
A 1 132 ILE 132 147 147 ILE ILE A . n 
A 1 133 THR 133 148 148 THR THR A . n 
A 1 134 GLY 134 149 149 GLY GLY A . n 
A 1 135 THR 135 150 150 THR THR A . n 
A 1 136 LYS 136 151 151 LYS LYS A . n 
A 1 137 LEU 137 152 152 LEU LEU A . n 
A 1 138 ASP 138 153 153 ASP ASP A . n 
A 1 139 SER 139 154 154 SER SER A . n 
A 1 140 SER 140 155 155 SER SER A . n 
A 1 141 GLY 141 156 156 GLY GLY A . n 
A 1 142 VAL 142 157 157 VAL VAL A . n 
A 1 143 ALA 143 158 158 ALA ALA A . n 
A 1 144 PHE 144 159 159 PHE PHE A . n 
A 1 145 ALA 145 160 160 ALA ALA A . n 
A 1 146 VAL 146 161 161 VAL VAL A . n 
A 1 147 VAL 147 162 162 VAL VAL A . n 
A 1 148 GLY 148 163 163 GLY GLY A . n 
A 1 149 ALA 149 164 164 ALA ALA A . n 
A 1 150 CYS 150 165 165 CYS CYS A . n 
A 1 151 GLN 151 166 166 GLN GLN A . n 
A 1 152 ALA 152 167 167 ALA ALA A . n 
A 1 153 LEU 153 168 168 LEU LEU A . n 
A 1 154 GLY 154 169 169 GLY GLY A . n 
A 1 155 LEU 155 170 170 LEU LEU A . n 
A 1 156 ARG 156 171 171 ARG ARG A . n 
A 1 157 ASP 157 172 172 ASP ASP A . n 
A 1 158 VAL 158 173 173 VAL VAL A . n 
A 1 159 HIS 159 174 174 HIS HIS A . n 
A 1 160 LEU 160 175 175 LEU LEU A . n 
A 1 161 ALA 161 176 176 ALA ALA A . n 
A 1 162 LEU 162 177 177 LEU LEU A . n 
A 1 163 SER 163 178 178 SER SER A . n 
A 1 164 GLU 164 179 179 GLU GLU A . n 
A 1 165 ASP 165 180 180 ASP ASP A . n 
A 1 166 HIS 166 181 181 HIS HIS A . n 
A 1 167 ALA 167 182 182 ALA ALA A . n 
A 1 168 TRP 168 183 183 TRP TRP A . n 
A 1 169 VAL 169 184 184 VAL VAL A . n 
A 1 170 VAL 170 185 185 VAL VAL A . n 
A 1 171 PHE 171 186 186 PHE PHE A . n 
A 1 172 GLY 172 187 187 GLY GLY A . n 
A 1 173 PRO 173 188 188 PRO PRO A . n 
A 1 174 ASN 174 189 189 ASN ASN A . n 
A 1 175 GLY 175 190 190 GLY GLY A . n 
A 1 176 GLU 176 191 191 GLU GLU A . n 
A 1 177 GLN 177 192 192 GLN GLN A . n 
A 1 178 THR 178 193 193 THR THR A . n 
A 1 179 ALA 179 194 194 ALA ALA A . n 
A 1 180 GLU 180 195 195 GLU GLU A . n 
A 1 181 VAL 181 196 196 VAL VAL A . n 
A 1 182 THR 182 197 197 THR THR A . n 
A 1 183 TRP 183 198 198 TRP TRP A . n 
A 1 184 HIS 184 199 199 HIS HIS A . n 
A 1 185 GLY 185 200 200 GLY GLY A . n 
A 1 186 LYS 186 201 201 LYS LYS A . n 
A 1 187 GLY 187 202 202 GLY GLY A . n 
A 1 188 ASN 188 203 203 ASN ASN A . n 
A 1 189 GLU 189 204 204 GLU GLU A . n 
A 1 190 ASP 190 205 205 ASP ASP A . n 
A 1 191 ARG 191 206 206 ARG ARG A . n 
A 1 192 ARG 192 207 207 ARG ARG A . n 
A 1 193 GLY 193 208 208 GLY GLY A . n 
A 1 194 GLN 194 209 209 GLN GLN A . n 
A 1 195 THR 195 210 210 THR THR A . n 
A 1 196 VAL 196 211 211 VAL VAL A . n 
A 1 197 ASN 197 212 212 ASN ASN A . n 
A 1 198 ALA 198 213 213 ALA ALA A . n 
A 1 199 GLY 199 214 214 GLY GLY A . n 
A 1 200 VAL 200 215 215 VAL VAL A . n 
A 1 201 ALA 201 216 216 ALA ALA A . n 
A 1 202 GLU 202 217 217 GLU GLU A . n 
A 1 203 ARG 203 218 218 ARG ARG A . n 
A 1 204 SER 204 219 219 SER SER A . n 
A 1 205 TRP 205 220 220 TRP TRP A . n 
A 1 206 LEU 206 221 221 LEU LEU A . n 
A 1 207 TYR 207 222 222 TYR TYR A . n 
A 1 208 LEU 208 223 223 LEU LEU A . n 
A 1 209 LYS 209 224 224 LYS LYS A . n 
A 1 210 GLY 210 225 225 GLY GLY A . n 
A 1 211 SER 211 226 226 SER SER A . n 
A 1 212 TYR 212 227 227 TYR TYR A . n 
A 1 213 MET 213 228 228 MET MET A . n 
A 1 214 ARG 214 229 229 ARG ARG A . n 
A 1 215 CYS 215 230 230 CYS CYS A . n 
A 1 216 ASP 216 231 231 ASP ASP A . n 
A 1 217 ARG 217 232 232 ARG ARG A . n 
A 1 218 LYS 218 233 233 LYS LYS A . n 
A 1 219 MET 219 234 234 MET MET A . n 
A 1 220 GLU 220 235 235 GLU GLU A . n 
A 1 221 VAL 221 236 236 VAL VAL A . n 
A 1 222 ALA 222 237 237 ALA ALA A . n 
A 1 223 PHE 223 238 238 PHE PHE A . n 
A 1 224 MET 224 239 239 MET MET A . n 
A 1 225 VAL 225 240 240 VAL VAL A . n 
A 1 226 CYS 226 241 241 CYS CYS A . n 
A 1 227 ALA 227 242 242 ALA ALA A . n 
A 1 228 ILE 228 243 243 ILE ILE A . n 
A 1 229 ASN 229 244 244 ASN ASN A . n 
A 1 230 PRO 230 245 245 PRO PRO A . n 
A 1 231 SER 231 246 246 SER SER A . n 
A 1 232 ILE 232 247 247 ILE ILE A . n 
A 1 233 ASP 233 248 248 ASP ASP A . n 
A 1 234 LEU 234 249 249 LEU LEU A . n 
A 1 235 HIS 235 250 250 HIS HIS A . n 
A 1 236 THR 236 251 251 THR THR A . n 
A 1 237 ASP 237 252 252 ASP ASP A . n 
A 1 238 SER 238 253 253 SER SER A . n 
A 1 239 LEU 239 254 254 LEU LEU A . n 
A 1 240 GLU 240 255 255 GLU GLU A . n 
A 1 241 LEU 241 256 256 LEU LEU A . n 
A 1 242 LEU 242 257 257 LEU LEU A . n 
A 1 243 GLN 243 258 258 GLN GLN A . n 
A 1 244 LEU 244 259 259 LEU LEU A . n 
A 1 245 GLN 245 260 260 GLN GLN A . n 
A 1 246 GLN 246 261 261 GLN GLN A . n 
A 1 247 LYS 247 262 262 LYS LYS A . n 
A 1 248 LEU 248 263 263 LEU LEU A . n 
A 1 249 LEU 249 264 264 LEU LEU A . n 
A 1 250 TRP 250 265 265 TRP TRP A . n 
A 1 251 LEU 251 266 266 LEU LEU A . n 
A 1 252 LEU 252 267 267 LEU LEU A . n 
A 1 253 TYR 253 268 268 TYR TYR A . n 
A 1 254 ASP 254 269 269 ASP ASP A . n 
A 1 255 LEU 255 270 270 LEU LEU A . n 
A 1 256 GLY 256 271 271 GLY GLY A . n 
A 1 257 HIS 257 272 272 HIS HIS A . n 
A 1 258 LEU 258 273 273 LEU LEU A . n 
A 1 259 GLU 259 274 274 GLU GLU A . n 
A 1 260 ARG 260 275 275 ARG ARG A . n 
A 1 261 TYR 261 276 276 TYR TYR A . n 
A 1 262 PRO 262 277 277 PRO PRO A . n 
A 1 263 MET 263 278 278 MET MET A . n 
A 1 264 ALA 264 279 279 ALA ALA A . n 
A 1 265 LEU 265 280 280 LEU LEU A . n 
A 1 266 GLY 266 281 281 GLY GLY A . n 
A 1 267 ASN 267 282 282 ASN ASN A . n 
A 1 268 LEU 268 283 283 LEU LEU A . n 
A 1 269 ALA 269 284 284 ALA ALA A . n 
A 1 270 ASP 270 285 285 ASP ASP A . n 
A 1 271 LEU 271 286 286 LEU LEU A . n 
A 1 272 GLU 272 287 287 GLU GLU A . n 
A 1 273 GLU 273 288 288 GLU GLU A . n 
A 1 274 LEU 274 289 289 LEU LEU A . n 
A 1 275 GLU 275 290 290 GLU GLU A . n 
A 1 276 PRO 276 291 291 PRO PRO A . n 
A 1 277 THR 277 292 292 THR THR A . n 
A 1 278 PRO 278 293 293 PRO PRO A . n 
A 1 279 GLY 279 294 294 GLY GLY A . n 
A 1 280 ARG 280 295 295 ARG ARG A . n 
A 1 281 PRO 281 296 296 PRO PRO A . n 
A 1 282 ASP 282 297 297 ASP ASP A . n 
A 1 283 PRO 283 298 298 PRO PRO A . n 
A 1 284 LEU 284 299 299 LEU LEU A . n 
A 1 285 THR 285 300 300 THR THR A . n 
A 1 286 LEU 286 301 301 LEU LEU A . n 
A 1 287 TYR 287 302 302 TYR TYR A . n 
A 1 288 HIS 288 303 303 HIS HIS A . n 
A 1 289 LYS 289 304 304 LYS LYS A . n 
A 1 290 GLY 290 305 305 GLY GLY A . n 
A 1 291 ILE 291 306 306 ILE ILE A . n 
A 1 292 ALA 292 307 307 ALA ALA A . n 
A 1 293 SER 293 308 308 SER SER A . n 
A 1 294 ALA 294 309 309 ALA ALA A . n 
A 1 295 LYS 295 310 310 LYS LYS A . n 
A 1 296 THR 296 311 311 THR THR A . n 
A 1 297 TYR 297 312 312 TYR TYR A . n 
A 1 298 TYR 298 313 313 TYR TYR A . n 
A 1 299 ARG 299 314 314 ARG ARG A . n 
A 1 300 ASP 300 315 315 ASP ASP A . n 
A 1 301 GLU 301 316 316 GLU GLU A . n 
A 1 302 HIS 302 317 317 HIS HIS A . n 
A 1 303 ILE 303 318 318 ILE ILE A . n 
A 1 304 TYR 304 319 319 TYR TYR A . n 
A 1 305 PRO 305 320 320 PRO PRO A . n 
A 1 306 TYR 306 321 321 TYR TYR A . n 
A 1 307 MET 307 322 322 MET MET A . n 
A 1 308 TYR 308 323 323 TYR TYR A . n 
A 1 309 LEU 309 324 324 LEU LEU A . n 
A 1 310 ALA 310 325 325 ALA ALA A . n 
A 1 311 GLY 311 326 326 GLY GLY A . n 
A 1 312 TYR 312 327 327 TYR TYR A . n 
A 1 313 HIS 313 328 328 HIS HIS A . n 
A 1 314 CYS 314 329 329 CYS CYS A . n 
A 1 315 ARG 315 330 330 ARG ARG A . n 
A 1 316 ASN 316 331 331 ASN ASN A . n 
A 1 317 ARG 317 332 332 ARG ARG A . n 
A 1 318 ASN 318 333 333 ASN ASN A . n 
A 1 319 VAL 319 334 334 VAL VAL A . n 
A 1 320 ARG 320 335 335 ARG ARG A . n 
A 1 321 GLU 321 336 336 GLU GLU A . n 
A 1 322 ALA 322 337 337 ALA ALA A . n 
A 1 323 LEU 323 338 338 LEU LEU A . n 
A 1 324 GLN 324 339 339 GLN GLN A . n 
A 1 325 ALA 325 340 340 ALA ALA A . n 
A 1 326 TRP 326 341 341 TRP TRP A . n 
A 1 327 ALA 327 342 342 ALA ALA A . n 
A 1 328 ASP 328 343 343 ASP ASP A . n 
A 1 329 THR 329 344 344 THR THR A . n 
A 1 330 ALA 330 345 345 ALA ALA A . n 
A 1 331 THR 331 346 346 THR THR A . n 
A 1 332 VAL 332 347 347 VAL VAL A . n 
A 1 333 ILE 333 348 348 ILE ILE A . n 
A 1 334 GLN 334 349 349 GLN GLN A . n 
A 1 335 ASP 335 350 350 ASP ASP A . n 
A 1 336 TYR 336 351 351 TYR TYR A . n 
A 1 337 ASN 337 352 352 ASN ASN A . n 
A 1 338 TYR 338 353 353 TYR TYR A . n 
A 1 339 CYS 339 354 354 CYS CYS A . n 
A 1 340 ARG 340 355 355 ARG ARG A . n 
A 1 341 GLU 341 356 356 GLU GLU A . n 
A 1 342 ASP 342 357 357 ASP ASP A . n 
A 1 343 GLU 343 358 358 GLU GLU A . n 
A 1 344 GLU 344 359 359 GLU GLU A . n 
A 1 345 ILE 345 360 360 ILE ILE A . n 
A 1 346 TYR 346 361 361 TYR TYR A . n 
A 1 347 LYS 347 362 362 LYS LYS A . n 
A 1 348 GLU 348 363 363 GLU GLU A . n 
A 1 349 PHE 349 364 364 PHE PHE A . n 
A 1 350 PHE 350 365 365 PHE PHE A . n 
A 1 351 GLU 351 366 366 GLU GLU A . n 
A 1 352 VAL 352 367 367 VAL VAL A . n 
A 1 353 ALA 353 368 368 ALA ALA A . n 
A 1 354 ASN 354 369 369 ASN ASN A . n 
A 1 355 ASP 355 370 370 ASP ASP A . n 
A 1 356 VAL 356 371 371 VAL VAL A . n 
A 1 357 ILE 357 372 372 ILE ILE A . n 
A 1 358 PRO 358 373 373 PRO PRO A . n 
A 1 359 ASN 359 374 374 ASN ASN A . n 
A 1 360 LEU 360 375 375 LEU LEU A . n 
A 1 361 LEU 361 376 376 LEU LEU A . n 
A 1 362 LYS 362 377 377 LYS LYS A . n 
A 1 363 GLU 363 378 378 GLU GLU A . n 
A 1 364 ALA 364 379 379 ALA ALA A . n 
A 1 365 ALA 365 380 380 ALA ALA A . n 
A 1 366 SER 366 381 381 SER SER A . n 
A 1 367 LEU 367 382 382 LEU LEU A . n 
A 1 368 LEU 368 383 383 LEU LEU A . n 
A 1 369 GLU 369 384 384 GLU GLU A . n 
A 1 370 ALA 370 385 385 ALA ALA A . n 
A 1 371 GLY 371 386 386 GLY GLY A . n 
A 1 372 SER 372 399 399 SER SER A . n 
A 1 373 GLN 373 400 400 GLN GLN A . n 
A 1 374 GLY 374 401 401 GLY GLY A . n 
A 1 375 SER 375 402 402 SER SER A . n 
A 1 376 ALA 376 403 403 ALA ALA A . n 
A 1 377 LEU 377 404 404 LEU LEU A . n 
A 1 378 GLN 378 405 405 GLN GLN A . n 
A 1 379 ASP 379 406 406 ASP ASP A . n 
A 1 380 PRO 380 407 407 PRO PRO A . n 
A 1 381 GLU 381 408 408 GLU GLU A . n 
A 1 382 CYS 382 409 409 CYS CYS A . n 
A 1 383 PHE 383 410 410 PHE PHE A . n 
A 1 384 ALA 384 411 411 ALA ALA A . n 
A 1 385 HIS 385 412 412 HIS HIS A . n 
A 1 386 LEU 386 413 413 LEU LEU A . n 
A 1 387 LEU 387 414 414 LEU LEU A . n 
A 1 388 ARG 388 415 415 ARG ARG A . n 
A 1 389 PHE 389 416 416 PHE PHE A . n 
A 1 390 TYR 390 417 417 TYR TYR A . n 
A 1 391 ASP 391 418 418 ASP ASP A . n 
A 1 392 GLY 392 419 419 GLY GLY A . n 
A 1 393 ILE 393 420 420 ILE ILE A . n 
A 1 394 CYS 394 421 421 CYS CYS A . n 
A 1 395 LYS 395 422 422 LYS LYS A . n 
A 1 396 TRP 396 423 423 TRP TRP A . n 
A 1 397 GLU 397 424 424 GLU GLU A . n 
A 1 398 GLU 398 425 425 GLU GLU A . n 
A 1 399 GLY 399 426 426 GLY GLY A . n 
A 1 400 SER 400 427 427 SER SER A . n 
A 1 401 PRO 401 428 428 PRO PRO A . n 
A 1 402 THR 402 429 429 THR THR A . n 
A 1 403 PRO 403 430 430 PRO PRO A . n 
A 1 404 VAL 404 431 431 VAL VAL A . n 
A 1 405 LEU 405 432 432 LEU LEU A . n 
A 1 406 HIS 406 433 433 HIS HIS A . n 
A 1 407 VAL 407 434 434 VAL VAL A . n 
A 1 408 GLY 408 435 435 GLY GLY A . n 
A 1 409 TRP 409 436 436 TRP TRP A . n 
A 1 410 ALA 410 437 437 ALA ALA A . n 
A 1 411 THR 411 438 438 THR THR A . n 
A 1 412 PHE 412 439 439 PHE PHE A . n 
A 1 413 LEU 413 440 440 LEU LEU A . n 
A 1 414 VAL 414 441 441 VAL VAL A . n 
A 1 415 GLN 415 442 442 GLN GLN A . n 
A 1 416 SER 416 443 443 SER SER A . n 
A 1 417 LEU 417 444 444 LEU LEU A . n 
A 1 418 GLY 418 445 445 GLY GLY A . n 
A 1 419 ARG 419 446 446 ARG ARG A . n 
A 1 420 PHE 420 447 447 PHE PHE A . n 
A 1 421 GLU 421 448 448 GLU GLU A . n 
A 1 422 GLY 422 449 449 GLY GLY A . n 
A 1 423 GLN 423 450 450 GLN GLN A . n 
A 1 424 VAL 424 451 451 VAL VAL A . n 
A 1 425 ARG 425 452 452 ARG ARG A . n 
A 1 426 GLN 426 453 453 GLN GLN A . n 
A 1 427 LYS 427 454 454 LYS LYS A . n 
A 1 428 VAL 428 455 455 VAL VAL A . n 
A 1 429 ARG 429 456 456 ARG ARG A . n 
A 1 430 ILE 430 457 457 ILE ILE A . n 
A 1 431 VAL 431 458 458 VAL VAL A . n 
A 1 432 SER 432 459 459 SER SER A . n 
A 1 433 VAL 433 460 460 VAL VAL A . n 
A 1 434 PRO 434 461 461 PRO PRO A . n 
A 1 435 ALA 435 539 ?   ?   ?   A . n 
A 1 436 PRO 436 540 ?   ?   ?   A . n 
A 1 437 THR 437 541 ?   ?   ?   A . n 
A 1 438 ALA 438 542 ?   ?   ?   A . n 
A 1 439 SER 439 543 ?   ?   ?   A . n 
A 1 440 PRO 440 544 ?   ?   ?   A . n 
A 1 441 PRO 441 545 ?   ?   ?   A . n 
A 1 442 PRO 442 546 ?   ?   ?   A . n 
A 1 443 GLU 443 547 ?   ?   ?   A . n 
A 1 444 GLY 444 548 ?   ?   ?   A . n 
A 1 445 PRO 445 549 549 PRO PRO A . n 
A 1 446 VAL 446 550 550 VAL VAL A . n 
A 1 447 LEU 447 551 551 LEU LEU A . n 
A 1 448 THR 448 552 552 THR THR A . n 
A 1 449 PHE 449 553 553 PHE PHE A . n 
A 1 450 GLN 450 554 554 GLN GLN A . n 
A 1 451 SER 451 555 555 SER SER A . n 
A 1 452 GLU 452 556 556 GLU GLU A . n 
A 1 453 LYS 453 557 557 LYS LYS A . n 
A 1 454 MET 454 558 558 MET MET A . n 
A 1 455 LYS 455 559 559 LYS LYS A . n 
A 1 456 GLY 456 560 560 GLY GLY A . n 
A 1 457 MET 457 561 561 MET MET A . n 
A 1 458 LYS 458 562 562 LYS LYS A . n 
A 1 459 GLU 459 563 563 GLU GLU A . n 
A 1 460 LEU 460 564 564 LEU LEU A . n 
A 1 461 LEU 461 565 565 LEU LEU A . n 
A 1 462 VAL 462 566 566 VAL VAL A . n 
A 1 463 ALA 463 567 567 ALA ALA A . n 
A 1 464 THR 464 568 568 THR THR A . n 
A 1 465 LYS 465 569 569 LYS LYS A . n 
A 1 466 ILE 466 570 570 ILE ILE A . n 
A 1 467 ASN 467 571 571 ASN ASN A . n 
A 1 468 SER 468 572 572 SER SER A . n 
A 1 469 SER 469 573 573 SER SER A . n 
A 1 470 ALA 470 574 574 ALA ALA A . n 
A 1 471 ILE 471 575 575 ILE ILE A . n 
A 1 472 LYS 472 576 576 LYS LYS A . n 
A 1 473 LEU 473 577 577 LEU LEU A . n 
A 1 474 GLN 474 578 578 GLN GLN A . n 
A 1 475 LEU 475 579 579 LEU LEU A . n 
A 1 476 THR 476 580 580 THR THR A . n 
A 1 477 ALA 477 581 581 ALA ALA A . n 
A 1 478 GLN 478 582 582 GLN GLN A . n 
A 1 479 SER 479 583 583 SER SER A . n 
A 1 480 GLN 480 584 584 GLN GLN A . n 
A 1 481 VAL 481 585 585 VAL VAL A . n 
A 1 482 GLN 482 586 586 GLN GLN A . n 
A 1 483 MET 483 587 587 MET MET A . n 
A 1 484 LYS 484 588 588 LYS LYS A . n 
A 1 485 LYS 485 589 ?   ?   ?   A . n 
A 1 486 GLN 486 590 ?   ?   ?   A . n 
A 1 487 LYS 487 591 ?   ?   ?   A . n 
A 1 488 VAL 488 592 ?   ?   ?   A . n 
A 1 489 SER 489 593 ?   ?   ?   A . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        K5O 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   K5O 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
B 2 K5O 1   601  1   K5O LIG A . 
C 3 PEG 1   602  1   PEG PEG A . 
D 3 PEG 1   603  2   PEG PEG A . 
E 4 SO4 1   604  3   SO4 SO4 A . 
F 5 DMS 1   605  4   DMS DMS A . 
G 6 PG4 1   606  5   PG4 PG4 A . 
H 4 SO4 1   607  6   SO4 SO4 A . 
I 6 PG4 1   608  7   PG4 PG4 A . 
J 4 SO4 1   609  8   SO4 SO4 A . 
K 5 DMS 1   610  9   DMS DMS A . 
L 7 EDO 1   611  10  EDO EDO A . 
M 8 HOH 1   701  202 HOH HOH A . 
M 8 HOH 2   702  58  HOH HOH A . 
M 8 HOH 3   703  23  HOH HOH A . 
M 8 HOH 4   704  198 HOH HOH A . 
M 8 HOH 5   705  284 HOH HOH A . 
M 8 HOH 6   706  348 HOH HOH A . 
M 8 HOH 7   707  346 HOH HOH A . 
M 8 HOH 8   708  94  HOH HOH A . 
M 8 HOH 9   709  75  HOH HOH A . 
M 8 HOH 10  710  108 HOH HOH A . 
M 8 HOH 11  711  219 HOH HOH A . 
M 8 HOH 12  712  286 HOH HOH A . 
M 8 HOH 13  713  168 HOH HOH A . 
M 8 HOH 14  714  181 HOH HOH A . 
M 8 HOH 15  715  114 HOH HOH A . 
M 8 HOH 16  716  362 HOH HOH A . 
M 8 HOH 17  717  178 HOH HOH A . 
M 8 HOH 18  718  195 HOH HOH A . 
M 8 HOH 19  719  297 HOH HOH A . 
M 8 HOH 20  720  30  HOH HOH A . 
M 8 HOH 21  721  301 HOH HOH A . 
M 8 HOH 22  722  289 HOH HOH A . 
M 8 HOH 23  723  143 HOH HOH A . 
M 8 HOH 24  724  146 HOH HOH A . 
M 8 HOH 25  725  95  HOH HOH A . 
M 8 HOH 26  726  211 HOH HOH A . 
M 8 HOH 27  727  332 HOH HOH A . 
M 8 HOH 28  728  214 HOH HOH A . 
M 8 HOH 29  729  147 HOH HOH A . 
M 8 HOH 30  730  111 HOH HOH A . 
M 8 HOH 31  731  158 HOH HOH A . 
M 8 HOH 32  732  192 HOH HOH A . 
M 8 HOH 33  733  187 HOH HOH A . 
M 8 HOH 34  734  62  HOH HOH A . 
M 8 HOH 35  735  196 HOH HOH A . 
M 8 HOH 36  736  148 HOH HOH A . 
M 8 HOH 37  737  254 HOH HOH A . 
M 8 HOH 38  738  193 HOH HOH A . 
M 8 HOH 39  739  252 HOH HOH A . 
M 8 HOH 40  740  109 HOH HOH A . 
M 8 HOH 41  741  279 HOH HOH A . 
M 8 HOH 42  742  135 HOH HOH A . 
M 8 HOH 43  743  209 HOH HOH A . 
M 8 HOH 44  744  188 HOH HOH A . 
M 8 HOH 45  745  367 HOH HOH A . 
M 8 HOH 46  746  103 HOH HOH A . 
M 8 HOH 47  747  38  HOH HOH A . 
M 8 HOH 48  748  175 HOH HOH A . 
M 8 HOH 49  749  144 HOH HOH A . 
M 8 HOH 50  750  11  HOH HOH A . 
M 8 HOH 51  751  63  HOH HOH A . 
M 8 HOH 52  752  155 HOH HOH A . 
M 8 HOH 53  753  342 HOH HOH A . 
M 8 HOH 54  754  204 HOH HOH A . 
M 8 HOH 55  755  18  HOH HOH A . 
M 8 HOH 56  756  87  HOH HOH A . 
M 8 HOH 57  757  225 HOH HOH A . 
M 8 HOH 58  758  239 HOH HOH A . 
M 8 HOH 59  759  131 HOH HOH A . 
M 8 HOH 60  760  54  HOH HOH A . 
M 8 HOH 61  761  357 HOH HOH A . 
M 8 HOH 62  762  190 HOH HOH A . 
M 8 HOH 63  763  335 HOH HOH A . 
M 8 HOH 64  764  37  HOH HOH A . 
M 8 HOH 65  765  72  HOH HOH A . 
M 8 HOH 66  766  317 HOH HOH A . 
M 8 HOH 67  767  205 HOH HOH A . 
M 8 HOH 68  768  253 HOH HOH A . 
M 8 HOH 69  769  255 HOH HOH A . 
M 8 HOH 70  770  227 HOH HOH A . 
M 8 HOH 71  771  100 HOH HOH A . 
M 8 HOH 72  772  7   HOH HOH A . 
M 8 HOH 73  773  123 HOH HOH A . 
M 8 HOH 74  774  33  HOH HOH A . 
M 8 HOH 75  775  199 HOH HOH A . 
M 8 HOH 76  776  349 HOH HOH A . 
M 8 HOH 77  777  338 HOH HOH A . 
M 8 HOH 78  778  46  HOH HOH A . 
M 8 HOH 79  779  361 HOH HOH A . 
M 8 HOH 80  780  82  HOH HOH A . 
M 8 HOH 81  781  51  HOH HOH A . 
M 8 HOH 82  782  80  HOH HOH A . 
M 8 HOH 83  783  40  HOH HOH A . 
M 8 HOH 84  784  45  HOH HOH A . 
M 8 HOH 85  785  238 HOH HOH A . 
M 8 HOH 86  786  170 HOH HOH A . 
M 8 HOH 87  787  35  HOH HOH A . 
M 8 HOH 88  788  44  HOH HOH A . 
M 8 HOH 89  789  365 HOH HOH A . 
M 8 HOH 90  790  156 HOH HOH A . 
M 8 HOH 91  791  355 HOH HOH A . 
M 8 HOH 92  792  232 HOH HOH A . 
M 8 HOH 93  793  27  HOH HOH A . 
M 8 HOH 94  794  160 HOH HOH A . 
M 8 HOH 95  795  28  HOH HOH A . 
M 8 HOH 96  796  19  HOH HOH A . 
M 8 HOH 97  797  59  HOH HOH A . 
M 8 HOH 98  798  21  HOH HOH A . 
M 8 HOH 99  799  200 HOH HOH A . 
M 8 HOH 100 800  47  HOH HOH A . 
M 8 HOH 101 801  137 HOH HOH A . 
M 8 HOH 102 802  29  HOH HOH A . 
M 8 HOH 103 803  151 HOH HOH A . 
M 8 HOH 104 804  217 HOH HOH A . 
M 8 HOH 105 805  115 HOH HOH A . 
M 8 HOH 106 806  93  HOH HOH A . 
M 8 HOH 107 807  233 HOH HOH A . 
M 8 HOH 108 808  116 HOH HOH A . 
M 8 HOH 109 809  167 HOH HOH A . 
M 8 HOH 110 810  174 HOH HOH A . 
M 8 HOH 111 811  24  HOH HOH A . 
M 8 HOH 112 812  119 HOH HOH A . 
M 8 HOH 113 813  6   HOH HOH A . 
M 8 HOH 114 814  157 HOH HOH A . 
M 8 HOH 115 815  9   HOH HOH A . 
M 8 HOH 116 816  3   HOH HOH A . 
M 8 HOH 117 817  311 HOH HOH A . 
M 8 HOH 118 818  74  HOH HOH A . 
M 8 HOH 119 819  83  HOH HOH A . 
M 8 HOH 120 820  22  HOH HOH A . 
M 8 HOH 121 821  172 HOH HOH A . 
M 8 HOH 122 822  71  HOH HOH A . 
M 8 HOH 123 823  105 HOH HOH A . 
M 8 HOH 124 824  67  HOH HOH A . 
M 8 HOH 125 825  26  HOH HOH A . 
M 8 HOH 126 826  1   HOH HOH A . 
M 8 HOH 127 827  49  HOH HOH A . 
M 8 HOH 128 828  341 HOH HOH A . 
M 8 HOH 129 829  159 HOH HOH A . 
M 8 HOH 130 830  179 HOH HOH A . 
M 8 HOH 131 831  107 HOH HOH A . 
M 8 HOH 132 832  12  HOH HOH A . 
M 8 HOH 133 833  96  HOH HOH A . 
M 8 HOH 134 834  228 HOH HOH A . 
M 8 HOH 135 835  81  HOH HOH A . 
M 8 HOH 136 836  173 HOH HOH A . 
M 8 HOH 137 837  16  HOH HOH A . 
M 8 HOH 138 838  129 HOH HOH A . 
M 8 HOH 139 839  122 HOH HOH A . 
M 8 HOH 140 840  43  HOH HOH A . 
M 8 HOH 141 841  50  HOH HOH A . 
M 8 HOH 142 842  13  HOH HOH A . 
M 8 HOH 143 843  141 HOH HOH A . 
M 8 HOH 144 844  201 HOH HOH A . 
M 8 HOH 145 845  65  HOH HOH A . 
M 8 HOH 146 846  36  HOH HOH A . 
M 8 HOH 147 847  57  HOH HOH A . 
M 8 HOH 148 848  247 HOH HOH A . 
M 8 HOH 149 849  183 HOH HOH A . 
M 8 HOH 150 850  169 HOH HOH A . 
M 8 HOH 151 851  97  HOH HOH A . 
M 8 HOH 152 852  55  HOH HOH A . 
M 8 HOH 153 853  32  HOH HOH A . 
M 8 HOH 154 854  2   HOH HOH A . 
M 8 HOH 155 855  127 HOH HOH A . 
M 8 HOH 156 856  90  HOH HOH A . 
M 8 HOH 157 857  14  HOH HOH A . 
M 8 HOH 158 858  230 HOH HOH A . 
M 8 HOH 159 859  39  HOH HOH A . 
M 8 HOH 160 860  334 HOH HOH A . 
M 8 HOH 161 861  112 HOH HOH A . 
M 8 HOH 162 862  250 HOH HOH A . 
M 8 HOH 163 863  249 HOH HOH A . 
M 8 HOH 164 864  10  HOH HOH A . 
M 8 HOH 165 865  113 HOH HOH A . 
M 8 HOH 166 866  106 HOH HOH A . 
M 8 HOH 167 867  216 HOH HOH A . 
M 8 HOH 168 868  98  HOH HOH A . 
M 8 HOH 169 869  134 HOH HOH A . 
M 8 HOH 170 870  231 HOH HOH A . 
M 8 HOH 171 871  304 HOH HOH A . 
M 8 HOH 172 872  226 HOH HOH A . 
M 8 HOH 173 873  66  HOH HOH A . 
M 8 HOH 174 874  370 HOH HOH A . 
M 8 HOH 175 875  76  HOH HOH A . 
M 8 HOH 176 876  354 HOH HOH A . 
M 8 HOH 177 877  128 HOH HOH A . 
M 8 HOH 178 878  242 HOH HOH A . 
M 8 HOH 179 879  213 HOH HOH A . 
M 8 HOH 180 880  64  HOH HOH A . 
M 8 HOH 181 881  124 HOH HOH A . 
M 8 HOH 182 882  70  HOH HOH A . 
M 8 HOH 183 883  42  HOH HOH A . 
M 8 HOH 184 884  15  HOH HOH A . 
M 8 HOH 185 885  85  HOH HOH A . 
M 8 HOH 186 886  104 HOH HOH A . 
M 8 HOH 187 887  25  HOH HOH A . 
M 8 HOH 188 888  176 HOH HOH A . 
M 8 HOH 189 889  126 HOH HOH A . 
M 8 HOH 190 890  117 HOH HOH A . 
M 8 HOH 191 891  110 HOH HOH A . 
M 8 HOH 192 892  149 HOH HOH A . 
M 8 HOH 193 893  41  HOH HOH A . 
M 8 HOH 194 894  118 HOH HOH A . 
M 8 HOH 195 895  17  HOH HOH A . 
M 8 HOH 196 896  34  HOH HOH A . 
M 8 HOH 197 897  86  HOH HOH A . 
M 8 HOH 198 898  218 HOH HOH A . 
M 8 HOH 199 899  130 HOH HOH A . 
M 8 HOH 200 900  350 HOH HOH A . 
M 8 HOH 201 901  125 HOH HOH A . 
M 8 HOH 202 902  164 HOH HOH A . 
M 8 HOH 203 903  162 HOH HOH A . 
M 8 HOH 204 904  8   HOH HOH A . 
M 8 HOH 205 905  136 HOH HOH A . 
M 8 HOH 206 906  189 HOH HOH A . 
M 8 HOH 207 907  244 HOH HOH A . 
M 8 HOH 208 908  234 HOH HOH A . 
M 8 HOH 209 909  53  HOH HOH A . 
M 8 HOH 210 910  206 HOH HOH A . 
M 8 HOH 211 911  154 HOH HOH A . 
M 8 HOH 212 912  4   HOH HOH A . 
M 8 HOH 213 913  92  HOH HOH A . 
M 8 HOH 214 914  120 HOH HOH A . 
M 8 HOH 215 915  321 HOH HOH A . 
M 8 HOH 216 916  101 HOH HOH A . 
M 8 HOH 217 917  339 HOH HOH A . 
M 8 HOH 218 918  241 HOH HOH A . 
M 8 HOH 219 919  68  HOH HOH A . 
M 8 HOH 220 920  20  HOH HOH A . 
M 8 HOH 221 921  78  HOH HOH A . 
M 8 HOH 222 922  314 HOH HOH A . 
M 8 HOH 223 923  359 HOH HOH A . 
M 8 HOH 224 924  246 HOH HOH A . 
M 8 HOH 225 925  161 HOH HOH A . 
M 8 HOH 226 926  223 HOH HOH A . 
M 8 HOH 227 927  52  HOH HOH A . 
M 8 HOH 228 928  371 HOH HOH A . 
M 8 HOH 229 929  88  HOH HOH A . 
M 8 HOH 230 930  139 HOH HOH A . 
M 8 HOH 231 931  5   HOH HOH A . 
M 8 HOH 232 932  194 HOH HOH A . 
M 8 HOH 233 933  207 HOH HOH A . 
M 8 HOH 234 934  48  HOH HOH A . 
M 8 HOH 235 935  315 HOH HOH A . 
M 8 HOH 236 936  256 HOH HOH A . 
M 8 HOH 237 937  132 HOH HOH A . 
M 8 HOH 238 938  270 HOH HOH A . 
M 8 HOH 239 939  31  HOH HOH A . 
M 8 HOH 240 940  152 HOH HOH A . 
M 8 HOH 241 941  285 HOH HOH A . 
M 8 HOH 242 942  182 HOH HOH A . 
M 8 HOH 243 943  73  HOH HOH A . 
M 8 HOH 244 944  61  HOH HOH A . 
M 8 HOH 245 945  56  HOH HOH A . 
M 8 HOH 246 946  69  HOH HOH A . 
M 8 HOH 247 947  191 HOH HOH A . 
M 8 HOH 248 948  77  HOH HOH A . 
M 8 HOH 249 949  324 HOH HOH A . 
M 8 HOH 250 950  288 HOH HOH A . 
M 8 HOH 251 951  142 HOH HOH A . 
M 8 HOH 252 952  171 HOH HOH A . 
M 8 HOH 253 953  267 HOH HOH A . 
M 8 HOH 254 954  99  HOH HOH A . 
M 8 HOH 255 955  185 HOH HOH A . 
M 8 HOH 256 956  299 HOH HOH A . 
M 8 HOH 257 957  102 HOH HOH A . 
M 8 HOH 258 958  245 HOH HOH A . 
M 8 HOH 259 959  257 HOH HOH A . 
M 8 HOH 260 960  220 HOH HOH A . 
M 8 HOH 261 961  215 HOH HOH A . 
M 8 HOH 262 962  277 HOH HOH A . 
M 8 HOH 263 963  140 HOH HOH A . 
M 8 HOH 264 964  60  HOH HOH A . 
M 8 HOH 265 965  251 HOH HOH A . 
M 8 HOH 266 966  264 HOH HOH A . 
M 8 HOH 267 967  236 HOH HOH A . 
M 8 HOH 268 968  248 HOH HOH A . 
M 8 HOH 269 969  153 HOH HOH A . 
M 8 HOH 270 970  210 HOH HOH A . 
M 8 HOH 271 971  358 HOH HOH A . 
M 8 HOH 272 972  240 HOH HOH A . 
M 8 HOH 273 973  316 HOH HOH A . 
M 8 HOH 274 974  121 HOH HOH A . 
M 8 HOH 275 975  293 HOH HOH A . 
M 8 HOH 276 976  329 HOH HOH A . 
M 8 HOH 277 977  221 HOH HOH A . 
M 8 HOH 278 978  313 HOH HOH A . 
M 8 HOH 279 979  89  HOH HOH A . 
M 8 HOH 280 980  91  HOH HOH A . 
M 8 HOH 281 981  356 HOH HOH A . 
M 8 HOH 282 982  280 HOH HOH A . 
M 8 HOH 283 983  292 HOH HOH A . 
M 8 HOH 284 984  326 HOH HOH A . 
M 8 HOH 285 985  337 HOH HOH A . 
M 8 HOH 286 986  336 HOH HOH A . 
M 8 HOH 287 987  328 HOH HOH A . 
M 8 HOH 288 988  351 HOH HOH A . 
M 8 HOH 289 989  224 HOH HOH A . 
M 8 HOH 290 990  222 HOH HOH A . 
M 8 HOH 291 991  265 HOH HOH A . 
M 8 HOH 292 992  138 HOH HOH A . 
M 8 HOH 293 993  186 HOH HOH A . 
M 8 HOH 294 994  208 HOH HOH A . 
M 8 HOH 295 995  276 HOH HOH A . 
M 8 HOH 296 996  330 HOH HOH A . 
M 8 HOH 297 997  260 HOH HOH A . 
M 8 HOH 298 998  150 HOH HOH A . 
M 8 HOH 299 999  327 HOH HOH A . 
M 8 HOH 300 1000 319 HOH HOH A . 
M 8 HOH 301 1001 133 HOH HOH A . 
M 8 HOH 302 1002 302 HOH HOH A . 
M 8 HOH 303 1003 309 HOH HOH A . 
M 8 HOH 304 1004 283 HOH HOH A . 
M 8 HOH 305 1005 345 HOH HOH A . 
M 8 HOH 306 1006 184 HOH HOH A . 
M 8 HOH 307 1007 333 HOH HOH A . 
M 8 HOH 308 1008 352 HOH HOH A . 
M 8 HOH 309 1009 368 HOH HOH A . 
M 8 HOH 310 1010 177 HOH HOH A . 
M 8 HOH 311 1011 308 HOH HOH A . 
M 8 HOH 312 1012 291 HOH HOH A . 
M 8 HOH 313 1013 353 HOH HOH A . 
M 8 HOH 314 1014 320 HOH HOH A . 
M 8 HOH 315 1015 318 HOH HOH A . 
M 8 HOH 316 1016 331 HOH HOH A . 
M 8 HOH 317 1017 259 HOH HOH A . 
M 8 HOH 318 1018 275 HOH HOH A . 
M 8 HOH 319 1019 271 HOH HOH A . 
M 8 HOH 320 1020 165 HOH HOH A . 
M 8 HOH 321 1021 312 HOH HOH A . 
M 8 HOH 322 1022 269 HOH HOH A . 
M 8 HOH 323 1023 263 HOH HOH A . 
M 8 HOH 324 1024 272 HOH HOH A . 
M 8 HOH 325 1025 212 HOH HOH A . 
M 8 HOH 326 1026 281 HOH HOH A . 
M 8 HOH 327 1027 282 HOH HOH A . 
M 8 HOH 328 1028 166 HOH HOH A . 
M 8 HOH 329 1029 295 HOH HOH A . 
M 8 HOH 330 1030 307 HOH HOH A . 
M 8 HOH 331 1031 290 HOH HOH A . 
M 8 HOH 332 1032 305 HOH HOH A . 
M 8 HOH 333 1033 180 HOH HOH A . 
M 8 HOH 334 1034 322 HOH HOH A . 
M 8 HOH 335 1035 343 HOH HOH A . 
M 8 HOH 336 1036 203 HOH HOH A . 
M 8 HOH 337 1037 258 HOH HOH A . 
M 8 HOH 338 1038 310 HOH HOH A . 
M 8 HOH 339 1039 274 HOH HOH A . 
M 8 HOH 340 1040 266 HOH HOH A . 
M 8 HOH 341 1041 197 HOH HOH A . 
M 8 HOH 342 1042 303 HOH HOH A . 
M 8 HOH 343 1043 323 HOH HOH A . 
M 8 HOH 344 1044 369 HOH HOH A . 
M 8 HOH 345 1045 347 HOH HOH A . 
M 8 HOH 346 1046 340 HOH HOH A . 
M 8 HOH 347 1047 145 HOH HOH A . 
M 8 HOH 348 1048 278 HOH HOH A . 
M 8 HOH 349 1049 325 HOH HOH A . 
M 8 HOH 350 1050 273 HOH HOH A . 
M 8 HOH 351 1051 84  HOH HOH A . 
M 8 HOH 352 1052 298 HOH HOH A . 
M 8 HOH 353 1053 306 HOH HOH A . 
M 8 HOH 354 1054 243 HOH HOH A . 
M 8 HOH 355 1055 364 HOH HOH A . 
M 8 HOH 356 1056 237 HOH HOH A . 
M 8 HOH 357 1057 262 HOH HOH A . 
M 8 HOH 358 1058 300 HOH HOH A . 
M 8 HOH 359 1059 261 HOH HOH A . 
M 8 HOH 360 1060 163 HOH HOH A . 
M 8 HOH 361 1061 360 HOH HOH A . 
M 8 HOH 362 1062 294 HOH HOH A . 
M 8 HOH 363 1063 79  HOH HOH A . 
M 8 HOH 364 1064 268 HOH HOH A . 
M 8 HOH 365 1065 296 HOH HOH A . 
M 8 HOH 366 1066 235 HOH HOH A . 
M 8 HOH 367 1067 287 HOH HOH A . 
M 8 HOH 368 1068 344 HOH HOH A . 
M 8 HOH 369 1069 366 HOH HOH A . 
M 8 HOH 370 1070 363 HOH HOH A . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 A GLY 2   ? N   ? A GLY 7   N   
2  1 Y 1 A GLY 2   ? CA  ? A GLY 7   CA  
3  1 Y 1 A GLU 109 ? CG  ? A GLU 94  CG  
4  1 Y 1 A GLU 109 ? CD  ? A GLU 94  CD  
5  1 Y 1 A GLU 109 ? OE1 ? A GLU 94  OE1 
6  1 Y 1 A GLU 109 ? OE2 ? A GLU 94  OE2 
7  1 Y 1 A LYS 201 ? CG  ? A LYS 186 CG  
8  1 Y 1 A LYS 201 ? CD  ? A LYS 186 CD  
9  1 Y 1 A LYS 201 ? CE  ? A LYS 186 CE  
10 1 Y 1 A LYS 201 ? NZ  ? A LYS 186 NZ  
11 1 Y 1 A GLU 204 ? CG  ? A GLU 189 CG  
12 1 Y 1 A GLU 204 ? CD  ? A GLU 189 CD  
13 1 Y 1 A GLU 204 ? OE1 ? A GLU 189 OE1 
14 1 Y 1 A GLU 204 ? OE2 ? A GLU 189 OE2 
15 1 Y 1 A HIS 250 ? CG  ? A HIS 235 CG  
16 1 Y 1 A HIS 250 ? ND1 ? A HIS 235 ND1 
17 1 Y 1 A HIS 250 ? CD2 ? A HIS 235 CD2 
18 1 Y 1 A HIS 250 ? CE1 ? A HIS 235 CE1 
19 1 Y 1 A HIS 250 ? NE2 ? A HIS 235 NE2 
20 1 Y 1 A ARG 456 ? CG  ? A ARG 429 CG  
21 1 Y 1 A ARG 456 ? CD  ? A ARG 429 CD  
22 1 Y 1 A ARG 456 ? NE  ? A ARG 429 NE  
23 1 Y 1 A ARG 456 ? CZ  ? A ARG 429 CZ  
24 1 Y 1 A ARG 456 ? NH1 ? A ARG 429 NH1 
25 1 Y 1 A ARG 456 ? NH2 ? A ARG 429 NH2 
26 1 Y 1 A GLN 586 ? CG  ? A GLN 482 CG  
27 1 Y 1 A GLN 586 ? CD  ? A GLN 482 CD  
28 1 Y 1 A GLN 586 ? OE1 ? A GLN 482 OE1 
29 1 Y 1 A GLN 586 ? NE2 ? A GLN 482 NE2 
30 1 Y 1 A MET 587 ? CG  ? A MET 483 CG  
31 1 Y 1 A MET 587 ? SD  ? A MET 483 SD  
32 1 Y 1 A MET 587 ? CE  ? A MET 483 CE  
33 1 Y 1 A LYS 588 ? CG  ? A LYS 484 CG  
34 1 Y 1 A LYS 588 ? CD  ? A LYS 484 CD  
35 1 Y 1 A LYS 588 ? CE  ? A LYS 484 CE  
36 1 Y 1 A LYS 588 ? NZ  ? A LYS 484 NZ  
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? REFMAC   ? ? ? 5.8.0419            1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? HKL-2000 ? ? ? 722                 2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? HKL-2000 ? ? ? 722                 3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? MOLREP   ? ? ? '11.0 /22.07.2010/' 4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8VA6 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     48.395 
_cell.length_a_esd                 ? 
_cell.length_b                     80.181 
_cell.length_b_esd                 ? 
_cell.length_c                     124.924 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        4 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8VA6 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                19 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 21 21 21' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8VA6 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.22 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          44.61 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              7.5 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '0.2 M lithium sulfate, 0.1 M HEPES, pH 7.5, 25% (w/v) PEG-3,350' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            277 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     CCD 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'MARMOSAIC 300 mm CCD' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2016-06-07 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.97857 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'APS BEAMLINE 21-ID-G' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.97857 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   21-ID-G 
_diffrn_source.pdbx_synchrotron_site       APS 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       8VA6 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              1.57 
_reflns.d_resolution_low                               50 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     68768 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           100 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                6.9 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          33.4 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   ? 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.072 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    1.57 
_reflns_shell.d_res_low                                     1.60 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           2.13 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             0 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               6.3 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  ? 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          100 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  0.772 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            1.513 
_refine.aniso_B[1][2]                            -0.000 
_refine.aniso_B[1][3]                            0.000 
_refine.aniso_B[2][2]                            0.053 
_refine.aniso_B[2][3]                            -0.000 
_refine.aniso_B[3][3]                            -1.566 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               23.252 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               0.974 
_refine.correlation_coeff_Fo_to_Fc_free          0.963 
_refine.details                                  'Hydrogens have been added in their riding positions' 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8VA6 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            1.570 
_refine.ls_d_res_low                             41.467 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     68695 
_refine.ls_number_reflns_R_free                  3434 
_refine.ls_number_reflns_R_work                  65261 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.952 
_refine.ls_percent_reflns_R_free                 4.999 
_refine.ls_R_factor_all                          0.160 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       0.1933 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1581 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'MASK BULK SOLVENT' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               THROUGHOUT 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       0.075 
_refine.pdbx_overall_ESU_R_Free                  0.079 
_refine.pdbx_solvent_vdw_probe_radii             1.200 
_refine.pdbx_solvent_ion_probe_radii             0.800 
_refine.pdbx_solvent_shrinkage_radii             0.800 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             1.577 
_refine.overall_SU_ML                            0.055 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.pdbx_number_atoms_protein        3670 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         116 
_refine_hist.number_atoms_solvent             370 
_refine_hist.number_atoms_total               4156 
_refine_hist.d_res_high                       1.570 
_refine_hist.d_res_low                        41.467 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.010  0.012  3963 ? r_bond_refined_d               ? ? 
'X-RAY DIFFRACTION' ? 0.001  0.016  3746 ? r_bond_other_d                 ? ? 
'X-RAY DIFFRACTION' ? 1.825  1.830  5382 ? r_angle_refined_deg            ? ? 
'X-RAY DIFFRACTION' ? 0.648  1.743  8602 ? r_angle_other_deg              ? ? 
'X-RAY DIFFRACTION' ? 6.130  5.000  485  ? r_dihedral_angle_1_deg         ? ? 
'X-RAY DIFFRACTION' ? 9.052  6.000  30   ? r_dihedral_angle_2_deg         ? ? 
'X-RAY DIFFRACTION' ? 4.733  20.000 2    ? r_dihedral_angle_other_2_deg   ? ? 
'X-RAY DIFFRACTION' ? 12.183 10.000 641  ? r_dihedral_angle_3_deg         ? ? 
'X-RAY DIFFRACTION' ? 15.077 10.000 176  ? r_dihedral_angle_6_deg         ? ? 
'X-RAY DIFFRACTION' ? 0.101  0.200  595  ? r_chiral_restr                 ? ? 
'X-RAY DIFFRACTION' ? 0.004  0.200  1    ? r_chiral_restr_other           ? ? 
'X-RAY DIFFRACTION' ? 0.009  0.020  4682 ? r_gen_planes_refined           ? ? 
'X-RAY DIFFRACTION' ? 0.001  0.020  928  ? r_gen_planes_other             ? ? 
'X-RAY DIFFRACTION' ? 0.222  0.200  805  ? r_nbd_refined                  ? ? 
'X-RAY DIFFRACTION' ? 0.183  0.200  3293 ? r_symmetry_nbd_other           ? ? 
'X-RAY DIFFRACTION' ? 0.183  0.200  1943 ? r_nbtor_refined                ? ? 
'X-RAY DIFFRACTION' ? 0.074  0.200  1970 ? r_symmetry_nbtor_other         ? ? 
'X-RAY DIFFRACTION' ? 0.135  0.200  227  ? r_xyhbond_nbd_refined          ? ? 
'X-RAY DIFFRACTION' ? 0.239  0.200  12   ? r_symmetry_nbd_refined         ? ? 
'X-RAY DIFFRACTION' ? 0.186  0.200  73   ? r_nbd_other                    ? ? 
'X-RAY DIFFRACTION' ? 0.279  0.200  16   ? r_symmetry_xyhbond_nbd_refined ? ? 
'X-RAY DIFFRACTION' ? 2.467  2.263  1918 ? r_mcbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 2.467  2.263  1918 ? r_mcbond_other                 ? ? 
'X-RAY DIFFRACTION' ? 3.662  4.055  2411 ? r_mcangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 3.663  4.057  2412 ? r_mcangle_other                ? ? 
'X-RAY DIFFRACTION' ? 3.729  2.625  2045 ? r_scbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 3.728  2.626  2046 ? r_scbond_other                 ? ? 
'X-RAY DIFFRACTION' ? 5.536  4.616  2971 ? r_scangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 5.535  4.617  2972 ? r_scangle_other                ? ? 
'X-RAY DIFFRACTION' ? 6.978  24.716 4546 ? r_lrange_it                    ? ? 
'X-RAY DIFFRACTION' ? 6.977  24.720 4547 ? r_lrange_other                 ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 1.570 1.611  5037 . 240 4780 99.6625  . 0.240 . . 0.240 . . . . . 0.215 . 20 . 0.955 0.957 0.240 
'X-RAY DIFFRACTION' 1.611 1.655  4852 . 260 4592 100.0000 . 0.217 . . 0.216 . . . . . 0.187 . 20 . 0.965 0.959 0.238 
'X-RAY DIFFRACTION' 1.655 1.703  4740 . 246 4494 100.0000 . 0.198 . . 0.196 . . . . . 0.168 . 20 . 0.972 0.958 0.242 
'X-RAY DIFFRACTION' 1.703 1.755  4621 . 244 4377 100.0000 . 0.195 . . 0.194 . . . . . 0.163 . 20 . 0.973 0.965 0.230 
'X-RAY DIFFRACTION' 1.755 1.812  4484 . 228 4256 100.0000 . 0.174 . . 0.172 . . . . . 0.143 . 20 . 0.980 0.967 0.217 
'X-RAY DIFFRACTION' 1.812 1.876  4350 . 209 4141 100.0000 . 0.165 . . 0.164 . . . . . 0.138 . 20 . 0.982 0.975 0.194 
'X-RAY DIFFRACTION' 1.876 1.947  4202 . 220 3982 100.0000 . 0.161 . . 0.158 . . . . . 0.133 . 20 . 0.983 0.972 0.211 
'X-RAY DIFFRACTION' 1.947 2.026  4053 . 212 3841 100.0000 . 0.151 . . 0.149 . . . . . 0.130 . 20 . 0.986 0.976 0.194 
'X-RAY DIFFRACTION' 2.026 2.116  3877 . 184 3693 100.0000 . 0.151 . . 0.148 . . . . . 0.131 . 20 . 0.986 0.972 0.211 
'X-RAY DIFFRACTION' 2.116 2.219  3706 . 170 3536 100.0000 . 0.146 . . 0.144 . . . . . 0.131 . 20 . 0.987 0.979 0.181 
'X-RAY DIFFRACTION' 2.219 2.338  3538 . 189 3349 100.0000 . 0.143 . . 0.140 . . . . . 0.130 . 20 . 0.988 0.977 0.184 
'X-RAY DIFFRACTION' 2.338 2.480  3362 . 171 3191 100.0000 . 0.142 . . 0.139 . . . . . 0.130 . 20 . 0.988 0.977 0.201 
'X-RAY DIFFRACTION' 2.480 2.650  3182 . 143 3039 100.0000 . 0.145 . . 0.144 . . . . . 0.138 . 20 . 0.987 0.981 0.174 
'X-RAY DIFFRACTION' 2.650 2.862  2973 . 153 2820 100.0000 . 0.148 . . 0.146 . . . . . 0.144 . 20 . 0.987 0.977 0.190 
'X-RAY DIFFRACTION' 2.862 3.133  2724 . 129 2595 100.0000 . 0.167 . . 0.165 . . . . . 0.168 . 20 . 0.984 0.973 0.211 
'X-RAY DIFFRACTION' 3.133 3.500  2489 . 130 2359 100.0000 . 0.162 . . 0.161 . . . . . 0.170 . 20 . 0.985 0.980 0.179 
'X-RAY DIFFRACTION' 3.500 4.037  2227 . 104 2123 100.0000 . 0.138 . . 0.138 . . . . . 0.151 . 20 . 0.989 0.989 0.151 
'X-RAY DIFFRACTION' 4.037 4.933  1896 . 97  1799 100.0000 . 0.141 . . 0.140 . . . . . 0.161 . 20 . 0.989 0.984 0.176 
'X-RAY DIFFRACTION' 4.933 6.927  1502 . 58  1444 100.0000 . 0.194 . . 0.193 . . . . . 0.219 . 20 . 0.983 0.979 0.207 
'X-RAY DIFFRACTION' 6.927 41.467 909  . 47  850  98.6799  . 0.184 . . 0.182 . . . . . 0.226 . 20 . 0.981 0.977 0.216 
# 
_struct.entry_id                     8VA6 
_struct.title                        'Menin in complex with Ziftomenib (KO-539)' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8VA6 
_struct_keywords.text            'PROTEIN BINDING' 
_struct_keywords.pdbx_keywords   'PROTEIN BINDING' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 3 ? 
E N N 4 ? 
F N N 5 ? 
G N N 6 ? 
H N N 4 ? 
I N N 6 ? 
J N N 4 ? 
K N N 5 ? 
L N N 7 ? 
M N N 8 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP MEN1_HUMAN O00255 ? 1 
;MGLKAAQKTLFPLRSIDDVVRLFAAELGREEPDLVLLSLVLGFVEHFLAVNRVIPTNVPELTFQPSPAPDPPGGLTYFPV
ADLSIIAALYARFTAQIRGAVDLSLYPREGGVSSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFITGTKLDSSGVAFA
VVGACQALGLRDVHLALSEDHAWVVFGPNGEQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLKGSYMRCDRKMEVAFMV
CAINPSIDLHTDSLELLQLQQKLLWLLYDLGHLERYPMALGNLADLEELEPTPGRPDPLTLYHKGIASAKTYYRDEHIYP
YMYLAGYHCRNRNVREALQAWADTATVIQDYNYCREDEEIYKEFFEVANDVIPNLLKEAASLLEAGEERPGEQSQGTQSQ
GSALQDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVRQKVRIVS
;
1   
2 UNP MEN1_HUMAN O00255 ? 1 VPAPTASPPPEGPVLTFQSEKMKGMKELLVATKINSSAIKLQLTAQSQVQMKKQKVS 537 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8VA6 A 6   ? 432 ? O00255 1   ? 459 ? 1   459 
2 2 8VA6 A 433 ? 489 ? O00255 537 ? 593 ? 460 593 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8VA6 GLY A 1 ? UNP O00255 ?   ?   'expression tag' -4 1  
1 8VA6 GLY A 2 ? UNP O00255 ?   ?   'expression tag' -3 2  
1 8VA6 SER A 3 ? UNP O00255 ?   ?   'expression tag' -2 3  
1 8VA6 SER A 4 ? UNP O00255 ?   ?   'expression tag' -1 4  
1 8VA6 SER A 5 ? UNP O00255 ?   ?   'expression tag' 0  5  
1 8VA6 ?   A ? ? UNP O00255 ILE 54  deletion         ?  6  
1 8VA6 ?   A ? ? UNP O00255 PRO 55  deletion         ?  7  
1 8VA6 ?   A ? ? UNP O00255 THR 56  deletion         ?  8  
1 8VA6 ?   A ? ? UNP O00255 ASN 57  deletion         ?  9  
1 8VA6 ?   A ? ? UNP O00255 VAL 58  deletion         ?  10 
1 8VA6 ?   A ? ? UNP O00255 PRO 59  deletion         ?  11 
1 8VA6 ?   A ? ? UNP O00255 GLU 60  deletion         ?  12 
1 8VA6 ?   A ? ? UNP O00255 LEU 61  deletion         ?  13 
1 8VA6 ?   A ? ? UNP O00255 THR 62  deletion         ?  14 
1 8VA6 ?   A ? ? UNP O00255 PHE 63  deletion         ?  15 
1 8VA6 ?   A ? ? UNP O00255 GLN 64  deletion         ?  16 
1 8VA6 ?   A ? ? UNP O00255 PRO 65  deletion         ?  17 
1 8VA6 ?   A ? ? UNP O00255 SER 66  deletion         ?  18 
1 8VA6 ?   A ? ? UNP O00255 PRO 67  deletion         ?  19 
1 8VA6 ?   A ? ? UNP O00255 ALA 68  deletion         ?  20 
1 8VA6 ?   A ? ? UNP O00255 PRO 69  deletion         ?  21 
1 8VA6 ?   A ? ? UNP O00255 ASP 70  deletion         ?  22 
1 8VA6 ?   A ? ? UNP O00255 PRO 71  deletion         ?  23 
1 8VA6 ?   A ? ? UNP O00255 PRO 72  deletion         ?  24 
1 8VA6 ?   A ? ? UNP O00255 GLY 73  deletion         ?  25 
1 8VA6 ?   A ? ? UNP O00255 GLU 387 deletion         ?  26 
1 8VA6 ?   A ? ? UNP O00255 GLU 388 deletion         ?  27 
1 8VA6 ?   A ? ? UNP O00255 ARG 389 deletion         ?  28 
1 8VA6 ?   A ? ? UNP O00255 PRO 390 deletion         ?  29 
1 8VA6 ?   A ? ? UNP O00255 GLY 391 deletion         ?  30 
1 8VA6 ?   A ? ? UNP O00255 GLU 392 deletion         ?  31 
1 8VA6 ?   A ? ? UNP O00255 GLN 393 deletion         ?  32 
1 8VA6 ?   A ? ? UNP O00255 SER 394 deletion         ?  33 
1 8VA6 ?   A ? ? UNP O00255 GLN 395 deletion         ?  34 
1 8VA6 ?   A ? ? UNP O00255 GLY 396 deletion         ?  35 
1 8VA6 ?   A ? ? UNP O00255 THR 397 deletion         ?  36 
1 8VA6 ?   A ? ? UNP O00255 GLN 398 deletion         ?  37 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   monomeric 
_pdbx_struct_assembly.oligomeric_count     1 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I,J,K,L,M 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 LYS A 9   ? THR A 14  ? LYS A 4   THR A 9   1 ? 6  
HELX_P HELX_P2  AA2 SER A 20  ? GLY A 33  ? SER A 15  GLY A 28  1 ? 14 
HELX_P HELX_P3  AA3 ASP A 38  ? VAL A 55  ? ASP A 33  VAL A 50  1 ? 18 
HELX_P HELX_P4  AA4 ASP A 67  ? VAL A 86  ? ASP A 82  VAL A 101 1 ? 20 
HELX_P HELX_P5  AA5 ASP A 87  ? TYR A 91  ? ASP A 102 TYR A 106 5 ? 5  
HELX_P HELX_P6  AA6 SER A 99  ? SER A 113 ? SER A 114 SER A 128 1 ? 15 
HELX_P HELX_P7  AA7 SER A 127 ? THR A 135 ? SER A 142 THR A 150 1 ? 9  
HELX_P HELX_P8  AA8 ASP A 138 ? LEU A 153 ? ASP A 153 LEU A 168 1 ? 16 
HELX_P HELX_P9  AA9 GLY A 172 ? GLU A 176 ? GLY A 187 GLU A 191 5 ? 5  
HELX_P HELX_P10 AB1 VAL A 196 ? GLU A 202 ? VAL A 211 GLU A 217 1 ? 7  
HELX_P HELX_P11 AB2 SER A 204 ? SER A 211 ? SER A 219 SER A 226 5 ? 8  
HELX_P HELX_P12 AB3 ASP A 216 ? ALA A 227 ? ASP A 231 ALA A 242 1 ? 12 
HELX_P HELX_P13 AB4 SER A 238 ? LEU A 255 ? SER A 253 LEU A 270 1 ? 18 
HELX_P HELX_P14 AB5 TYR A 261 ? GLU A 275 ? TYR A 276 GLU A 290 1 ? 15 
HELX_P HELX_P15 AB6 ASP A 282 ? TYR A 298 ? ASP A 297 TYR A 313 1 ? 17 
HELX_P HELX_P16 AB7 ILE A 303 ? ASN A 316 ? ILE A 318 ASN A 331 1 ? 14 
HELX_P HELX_P17 AB8 ASN A 318 ? GLN A 334 ? ASN A 333 GLN A 349 1 ? 17 
HELX_P HELX_P18 AB9 ASP A 342 ? ASP A 355 ? ASP A 357 ASP A 370 1 ? 14 
HELX_P HELX_P19 AC1 ASP A 355 ? ALA A 370 ? ASP A 370 ALA A 385 1 ? 16 
HELX_P HELX_P20 AC2 SER A 375 ? GLN A 378 ? SER A 402 GLN A 405 5 ? 4  
HELX_P HELX_P21 AC3 ASP A 379 ? GLU A 398 ? ASP A 406 GLU A 425 1 ? 20 
HELX_P HELX_P22 AC4 HIS A 406 ? ARG A 419 ? HIS A 433 ARG A 446 1 ? 14 
HELX_P HELX_P23 AC5 GLU A 421 ? GLN A 426 ? GLU A 448 GLN A 453 1 ? 6  
HELX_P HELX_P24 AC6 SER A 451 ? VAL A 462 ? SER A 555 VAL A 566 1 ? 12 
HELX_P HELX_P25 AC7 ASN A 467 ? ALA A 477 ? ASN A 571 ALA A 581 1 ? 11 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 PHE 16  A . ? PHE 11  A PRO 17  A ? PRO 12  A 1 -0.97 
2 VAL 433 A . ? VAL 460 A PRO 434 A ? PRO 461 A 1 7.70  
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 4 ? 
AA2 ? 2 ? 
AA3 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA3 1 2 ? parallel      
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 GLN A 177 ? ALA A 179 ? GLN A 192 ALA A 194 
AA1 2 ALA A 167 ? PHE A 171 ? ALA A 182 PHE A 186 
AA1 3 HIS A 159 ? LEU A 162 ? HIS A 174 LEU A 177 
AA1 4 MET A 213 ? ARG A 214 ? MET A 228 ARG A 229 
AA2 1 SER A 231 ? ASP A 233 ? SER A 246 ASP A 248 
AA2 2 THR A 236 ? ASP A 237 ? THR A 251 ASP A 252 
AA3 1 ARG A 429 ? VAL A 431 ? ARG A 456 VAL A 458 
AA3 2 VAL A 446 ? THR A 448 ? VAL A 550 THR A 552 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O ALA A 179 ? O ALA A 194 N VAL A 169 ? N VAL A 184 
AA1 2 3 O TRP A 168 ? O TRP A 183 N ALA A 161 ? N ALA A 176 
AA1 3 4 N LEU A 162 ? N LEU A 177 O MET A 213 ? O MET A 228 
AA2 1 2 N ILE A 232 ? N ILE A 247 O THR A 236 ? O THR A 251 
AA3 1 2 N ARG A 429 ? N ARG A 456 O LEU A 447 ? O LEU A 551 
# 
_pdbx_entry_details.entry_id                   8VA6 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 NH1 A ARG 137 ? ? O A HOH 701 ? ? 2.01 
2 1 O   A HOH 941 ? ? O A HOH 978 ? ? 2.17 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1 1 CD A ARG 21  ? ? NE A ARG 21  ? ? CZ  A ARG 21  ? ? 132.94 123.60 9.34  1.40 N 
2 1 NE A ARG 21  ? ? CZ A ARG 21  ? ? NH1 A ARG 21  ? ? 124.27 120.30 3.97  0.50 N 
3 1 NE A ARG 21  ? ? CZ A ARG 21  ? ? NH2 A ARG 21  ? ? 116.59 120.30 -3.71 0.50 N 
4 1 NE A ARG 314 ? A CZ A ARG 314 ? A NH2 A ARG 314 ? A 116.52 120.30 -3.78 0.50 N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 TYR A 77  ? ? -157.51 -56.59  
2 1 ASP A 180 ? ? -151.36 17.05   
3 1 GLU A 204 ? ? -92.42  -150.88 
4 1 ASP A 205 ? ? -157.22 -78.84  
5 1 SER A 226 ? ? -91.86  46.03   
6 1 GLU A 290 ? ? -151.45 89.95   
7 1 ASP A 370 ? ? -137.35 -53.25  
# 
loop_
_pdbx_validate_planes.id 
_pdbx_validate_planes.PDB_model_num 
_pdbx_validate_planes.auth_comp_id 
_pdbx_validate_planes.auth_asym_id 
_pdbx_validate_planes.auth_seq_id 
_pdbx_validate_planes.PDB_ins_code 
_pdbx_validate_planes.label_alt_id 
_pdbx_validate_planes.rmsd 
_pdbx_validate_planes.type 
1 1 ARG A 21  ? ? 0.121 'SIDE CHAIN' 
2 1 ARG A 137 ? ? 0.111 'SIDE CHAIN' 
3 1 ARG A 207 ? ? 0.085 'SIDE CHAIN' 
# 
loop_
_pdbx_distant_solvent_atoms.id 
_pdbx_distant_solvent_atoms.PDB_model_num 
_pdbx_distant_solvent_atoms.auth_atom_id 
_pdbx_distant_solvent_atoms.label_alt_id 
_pdbx_distant_solvent_atoms.auth_asym_id 
_pdbx_distant_solvent_atoms.auth_comp_id 
_pdbx_distant_solvent_atoms.auth_seq_id 
_pdbx_distant_solvent_atoms.PDB_ins_code 
_pdbx_distant_solvent_atoms.neighbor_macromolecule_distance 
_pdbx_distant_solvent_atoms.neighbor_ligand_distance 
1 1 O ? A HOH 1068 ? 5.90 . 
2 1 O ? A HOH 1069 ? 6.25 . 
3 1 O ? A HOH 1070 ? 7.41 . 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A GLY -4  ? A GLY 1   
2  1 Y 1 A GLY -3  ? A GLY 2   
3  1 Y 1 A SER -2  ? A SER 3   
4  1 Y 1 A SER -1  ? A SER 4   
5  1 Y 1 A SER 0   ? A SER 5   
6  1 Y 1 A MET 1   ? A MET 6   
7  1 Y 1 A ALA 539 ? A ALA 435 
8  1 Y 1 A PRO 540 ? A PRO 436 
9  1 Y 1 A THR 541 ? A THR 437 
10 1 Y 1 A ALA 542 ? A ALA 438 
11 1 Y 1 A SER 543 ? A SER 439 
12 1 Y 1 A PRO 544 ? A PRO 440 
13 1 Y 1 A PRO 545 ? A PRO 441 
14 1 Y 1 A PRO 546 ? A PRO 442 
15 1 Y 1 A GLU 547 ? A GLU 443 
16 1 Y 1 A GLY 548 ? A GLY 444 
17 1 Y 1 A LYS 589 ? A LYS 485 
18 1 Y 1 A GLN 590 ? A GLN 486 
19 1 Y 1 A LYS 591 ? A LYS 487 
20 1 Y 1 A VAL 592 ? A VAL 488 
21 1 Y 1 A SER 593 ? A SER 489 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
DMS S    S N N 88  
DMS O    O N N 89  
DMS C1   C N N 90  
DMS C2   C N N 91  
DMS H11  H N N 92  
DMS H12  H N N 93  
DMS H13  H N N 94  
DMS H21  H N N 95  
DMS H22  H N N 96  
DMS H23  H N N 97  
EDO C1   C N N 98  
EDO O1   O N N 99  
EDO C2   C N N 100 
EDO O2   O N N 101 
EDO H11  H N N 102 
EDO H12  H N N 103 
EDO HO1  H N N 104 
EDO H21  H N N 105 
EDO H22  H N N 106 
EDO HO2  H N N 107 
GLN N    N N N 108 
GLN CA   C N S 109 
GLN C    C N N 110 
GLN O    O N N 111 
GLN CB   C N N 112 
GLN CG   C N N 113 
GLN CD   C N N 114 
GLN OE1  O N N 115 
GLN NE2  N N N 116 
GLN OXT  O N N 117 
GLN H    H N N 118 
GLN H2   H N N 119 
GLN HA   H N N 120 
GLN HB2  H N N 121 
GLN HB3  H N N 122 
GLN HG2  H N N 123 
GLN HG3  H N N 124 
GLN HE21 H N N 125 
GLN HE22 H N N 126 
GLN HXT  H N N 127 
GLU N    N N N 128 
GLU CA   C N S 129 
GLU C    C N N 130 
GLU O    O N N 131 
GLU CB   C N N 132 
GLU CG   C N N 133 
GLU CD   C N N 134 
GLU OE1  O N N 135 
GLU OE2  O N N 136 
GLU OXT  O N N 137 
GLU H    H N N 138 
GLU H2   H N N 139 
GLU HA   H N N 140 
GLU HB2  H N N 141 
GLU HB3  H N N 142 
GLU HG2  H N N 143 
GLU HG3  H N N 144 
GLU HE2  H N N 145 
GLU HXT  H N N 146 
GLY N    N N N 147 
GLY CA   C N N 148 
GLY C    C N N 149 
GLY O    O N N 150 
GLY OXT  O N N 151 
GLY H    H N N 152 
GLY H2   H N N 153 
GLY HA2  H N N 154 
GLY HA3  H N N 155 
GLY HXT  H N N 156 
HIS N    N N N 157 
HIS CA   C N S 158 
HIS C    C N N 159 
HIS O    O N N 160 
HIS CB   C N N 161 
HIS CG   C Y N 162 
HIS ND1  N Y N 163 
HIS CD2  C Y N 164 
HIS CE1  C Y N 165 
HIS NE2  N Y N 166 
HIS OXT  O N N 167 
HIS H    H N N 168 
HIS H2   H N N 169 
HIS HA   H N N 170 
HIS HB2  H N N 171 
HIS HB3  H N N 172 
HIS HD1  H N N 173 
HIS HD2  H N N 174 
HIS HE1  H N N 175 
HIS HE2  H N N 176 
HIS HXT  H N N 177 
HOH O    O N N 178 
HOH H1   H N N 179 
HOH H2   H N N 180 
ILE N    N N N 181 
ILE CA   C N S 182 
ILE C    C N N 183 
ILE O    O N N 184 
ILE CB   C N S 185 
ILE CG1  C N N 186 
ILE CG2  C N N 187 
ILE CD1  C N N 188 
ILE OXT  O N N 189 
ILE H    H N N 190 
ILE H2   H N N 191 
ILE HA   H N N 192 
ILE HB   H N N 193 
ILE HG12 H N N 194 
ILE HG13 H N N 195 
ILE HG21 H N N 196 
ILE HG22 H N N 197 
ILE HG23 H N N 198 
ILE HD11 H N N 199 
ILE HD12 H N N 200 
ILE HD13 H N N 201 
ILE HXT  H N N 202 
K5O C1   C N N 203 
K5O N1   N N N 204 
K5O C2   C Y N 205 
K5O N2   N Y N 206 
K5O C3   C Y N 207 
K5O N3   N N N 208 
K5O C4   C N N 209 
K5O C5   C N N 210 
K5O C6   C N N 211 
K5O N4   N N N 212 
K5O C7   C N N 213 
K5O C8   C Y N 214 
K5O C9   C Y N 215 
K5O C10  C Y N 216 
K5O C11  C Y N 217 
K5O N5   N Y N 218 
K5O C12  C N N 219 
K5O C13  C N S 220 
K5O C14  C N N 221 
K5O N6   N N N 222 
K5O C15  C N N 223 
K5O C16  C N N 224 
K5O N7   N N N 225 
K5O C17  C N N 226 
K5O C18  C N N 227 
K5O S1   S N N 228 
K5O C19  C N N 229 
K5O O1   O N N 230 
K5O O2   O N N 231 
K5O C20  C Y N 232 
K5O C21  C Y N 233 
K5O C22  C Y N 234 
K5O C23  C Y N 235 
K5O C24  C N N 236 
K5O C25  C N N 237 
K5O N8   N N N 238 
K5O C26  C N N 239 
K5O C27  C N N 240 
K5O C28  C Y N 241 
K5O C29  C Y N 242 
K5O C30  C Y N 243 
K5O C31  C N N 244 
K5O C32  C N N 245 
K5O F1   F N N 246 
K5O F2   F N N 247 
K5O F3   F N N 248 
K5O S2   S Y N 249 
K5O C33  C Y N 250 
K5O N9   N Y N 251 
K5O H1   H N N 252 
K5O H2   H N N 253 
K5O H3   H N N 254 
K5O H4   H N N 255 
K5O H5   H N N 256 
K5O H6   H N N 257 
K5O H7   H N N 258 
K5O H8   H N N 259 
K5O H9   H N N 260 
K5O H10  H N N 261 
K5O H12  H N N 262 
K5O H13  H N N 263 
K5O H14  H N N 264 
K5O H15  H N N 265 
K5O H16  H N N 266 
K5O H17  H N N 267 
K5O H18  H N N 268 
K5O H19  H N N 269 
K5O H20  H N N 270 
K5O H21  H N N 271 
K5O H23  H N N 272 
K5O H24  H N N 273 
K5O H25  H N N 274 
K5O H26  H N N 275 
K5O H27  H N N 276 
K5O H28  H N N 277 
K5O H29  H N N 278 
K5O H30  H N N 279 
K5O H31  H N N 280 
K5O H32  H N N 281 
K5O H33  H N N 282 
K5O H34  H N N 283 
K5O H35  H N N 284 
K5O H36  H N N 285 
K5O H37  H N N 286 
K5O H38  H N N 287 
K5O H39  H N N 288 
K5O H40  H N N 289 
K5O H41  H N N 290 
K5O H42  H N N 291 
K5O H43  H N N 292 
K5O H44  H N N 293 
LEU N    N N N 294 
LEU CA   C N S 295 
LEU C    C N N 296 
LEU O    O N N 297 
LEU CB   C N N 298 
LEU CG   C N N 299 
LEU CD1  C N N 300 
LEU CD2  C N N 301 
LEU OXT  O N N 302 
LEU H    H N N 303 
LEU H2   H N N 304 
LEU HA   H N N 305 
LEU HB2  H N N 306 
LEU HB3  H N N 307 
LEU HG   H N N 308 
LEU HD11 H N N 309 
LEU HD12 H N N 310 
LEU HD13 H N N 311 
LEU HD21 H N N 312 
LEU HD22 H N N 313 
LEU HD23 H N N 314 
LEU HXT  H N N 315 
LYS N    N N N 316 
LYS CA   C N S 317 
LYS C    C N N 318 
LYS O    O N N 319 
LYS CB   C N N 320 
LYS CG   C N N 321 
LYS CD   C N N 322 
LYS CE   C N N 323 
LYS NZ   N N N 324 
LYS OXT  O N N 325 
LYS H    H N N 326 
LYS H2   H N N 327 
LYS HA   H N N 328 
LYS HB2  H N N 329 
LYS HB3  H N N 330 
LYS HG2  H N N 331 
LYS HG3  H N N 332 
LYS HD2  H N N 333 
LYS HD3  H N N 334 
LYS HE2  H N N 335 
LYS HE3  H N N 336 
LYS HZ1  H N N 337 
LYS HZ2  H N N 338 
LYS HZ3  H N N 339 
LYS HXT  H N N 340 
MET N    N N N 341 
MET CA   C N S 342 
MET C    C N N 343 
MET O    O N N 344 
MET CB   C N N 345 
MET CG   C N N 346 
MET SD   S N N 347 
MET CE   C N N 348 
MET OXT  O N N 349 
MET H    H N N 350 
MET H2   H N N 351 
MET HA   H N N 352 
MET HB2  H N N 353 
MET HB3  H N N 354 
MET HG2  H N N 355 
MET HG3  H N N 356 
MET HE1  H N N 357 
MET HE2  H N N 358 
MET HE3  H N N 359 
MET HXT  H N N 360 
PEG C1   C N N 361 
PEG O1   O N N 362 
PEG C2   C N N 363 
PEG O2   O N N 364 
PEG C3   C N N 365 
PEG C4   C N N 366 
PEG O4   O N N 367 
PEG H11  H N N 368 
PEG H12  H N N 369 
PEG HO1  H N N 370 
PEG H21  H N N 371 
PEG H22  H N N 372 
PEG H31  H N N 373 
PEG H32  H N N 374 
PEG H41  H N N 375 
PEG H42  H N N 376 
PEG HO4  H N N 377 
PG4 O1   O N N 378 
PG4 C1   C N N 379 
PG4 C2   C N N 380 
PG4 O2   O N N 381 
PG4 C3   C N N 382 
PG4 C4   C N N 383 
PG4 O3   O N N 384 
PG4 C5   C N N 385 
PG4 C6   C N N 386 
PG4 O4   O N N 387 
PG4 C7   C N N 388 
PG4 C8   C N N 389 
PG4 O5   O N N 390 
PG4 HO1  H N N 391 
PG4 H11  H N N 392 
PG4 H12  H N N 393 
PG4 H21  H N N 394 
PG4 H22  H N N 395 
PG4 H31  H N N 396 
PG4 H32  H N N 397 
PG4 H41  H N N 398 
PG4 H42  H N N 399 
PG4 H51  H N N 400 
PG4 H52  H N N 401 
PG4 H61  H N N 402 
PG4 H62  H N N 403 
PG4 H71  H N N 404 
PG4 H72  H N N 405 
PG4 H81  H N N 406 
PG4 H82  H N N 407 
PG4 HO5  H N N 408 
PHE N    N N N 409 
PHE CA   C N S 410 
PHE C    C N N 411 
PHE O    O N N 412 
PHE CB   C N N 413 
PHE CG   C Y N 414 
PHE CD1  C Y N 415 
PHE CD2  C Y N 416 
PHE CE1  C Y N 417 
PHE CE2  C Y N 418 
PHE CZ   C Y N 419 
PHE OXT  O N N 420 
PHE H    H N N 421 
PHE H2   H N N 422 
PHE HA   H N N 423 
PHE HB2  H N N 424 
PHE HB3  H N N 425 
PHE HD1  H N N 426 
PHE HD2  H N N 427 
PHE HE1  H N N 428 
PHE HE2  H N N 429 
PHE HZ   H N N 430 
PHE HXT  H N N 431 
PRO N    N N N 432 
PRO CA   C N S 433 
PRO C    C N N 434 
PRO O    O N N 435 
PRO CB   C N N 436 
PRO CG   C N N 437 
PRO CD   C N N 438 
PRO OXT  O N N 439 
PRO H    H N N 440 
PRO HA   H N N 441 
PRO HB2  H N N 442 
PRO HB3  H N N 443 
PRO HG2  H N N 444 
PRO HG3  H N N 445 
PRO HD2  H N N 446 
PRO HD3  H N N 447 
PRO HXT  H N N 448 
SER N    N N N 449 
SER CA   C N S 450 
SER C    C N N 451 
SER O    O N N 452 
SER CB   C N N 453 
SER OG   O N N 454 
SER OXT  O N N 455 
SER H    H N N 456 
SER H2   H N N 457 
SER HA   H N N 458 
SER HB2  H N N 459 
SER HB3  H N N 460 
SER HG   H N N 461 
SER HXT  H N N 462 
SO4 S    S N N 463 
SO4 O1   O N N 464 
SO4 O2   O N N 465 
SO4 O3   O N N 466 
SO4 O4   O N N 467 
THR N    N N N 468 
THR CA   C N S 469 
THR C    C N N 470 
THR O    O N N 471 
THR CB   C N R 472 
THR OG1  O N N 473 
THR CG2  C N N 474 
THR OXT  O N N 475 
THR H    H N N 476 
THR H2   H N N 477 
THR HA   H N N 478 
THR HB   H N N 479 
THR HG1  H N N 480 
THR HG21 H N N 481 
THR HG22 H N N 482 
THR HG23 H N N 483 
THR HXT  H N N 484 
TRP N    N N N 485 
TRP CA   C N S 486 
TRP C    C N N 487 
TRP O    O N N 488 
TRP CB   C N N 489 
TRP CG   C Y N 490 
TRP CD1  C Y N 491 
TRP CD2  C Y N 492 
TRP NE1  N Y N 493 
TRP CE2  C Y N 494 
TRP CE3  C Y N 495 
TRP CZ2  C Y N 496 
TRP CZ3  C Y N 497 
TRP CH2  C Y N 498 
TRP OXT  O N N 499 
TRP H    H N N 500 
TRP H2   H N N 501 
TRP HA   H N N 502 
TRP HB2  H N N 503 
TRP HB3  H N N 504 
TRP HD1  H N N 505 
TRP HE1  H N N 506 
TRP HE3  H N N 507 
TRP HZ2  H N N 508 
TRP HZ3  H N N 509 
TRP HH2  H N N 510 
TRP HXT  H N N 511 
TYR N    N N N 512 
TYR CA   C N S 513 
TYR C    C N N 514 
TYR O    O N N 515 
TYR CB   C N N 516 
TYR CG   C Y N 517 
TYR CD1  C Y N 518 
TYR CD2  C Y N 519 
TYR CE1  C Y N 520 
TYR CE2  C Y N 521 
TYR CZ   C Y N 522 
TYR OH   O N N 523 
TYR OXT  O N N 524 
TYR H    H N N 525 
TYR H2   H N N 526 
TYR HA   H N N 527 
TYR HB2  H N N 528 
TYR HB3  H N N 529 
TYR HD1  H N N 530 
TYR HD2  H N N 531 
TYR HE1  H N N 532 
TYR HE2  H N N 533 
TYR HH   H N N 534 
TYR HXT  H N N 535 
VAL N    N N N 536 
VAL CA   C N S 537 
VAL C    C N N 538 
VAL O    O N N 539 
VAL CB   C N N 540 
VAL CG1  C N N 541 
VAL CG2  C N N 542 
VAL OXT  O N N 543 
VAL H    H N N 544 
VAL H2   H N N 545 
VAL HA   H N N 546 
VAL HB   H N N 547 
VAL HG11 H N N 548 
VAL HG12 H N N 549 
VAL HG13 H N N 550 
VAL HG21 H N N 551 
VAL HG22 H N N 552 
VAL HG23 H N N 553 
VAL HXT  H N N 554 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
DMS S   O    doub N N 83  
DMS S   C1   sing N N 84  
DMS S   C2   sing N N 85  
DMS C1  H11  sing N N 86  
DMS C1  H12  sing N N 87  
DMS C1  H13  sing N N 88  
DMS C2  H21  sing N N 89  
DMS C2  H22  sing N N 90  
DMS C2  H23  sing N N 91  
EDO C1  O1   sing N N 92  
EDO C1  C2   sing N N 93  
EDO C1  H11  sing N N 94  
EDO C1  H12  sing N N 95  
EDO O1  HO1  sing N N 96  
EDO C2  O2   sing N N 97  
EDO C2  H21  sing N N 98  
EDO C2  H22  sing N N 99  
EDO O2  HO2  sing N N 100 
GLN N   CA   sing N N 101 
GLN N   H    sing N N 102 
GLN N   H2   sing N N 103 
GLN CA  C    sing N N 104 
GLN CA  CB   sing N N 105 
GLN CA  HA   sing N N 106 
GLN C   O    doub N N 107 
GLN C   OXT  sing N N 108 
GLN CB  CG   sing N N 109 
GLN CB  HB2  sing N N 110 
GLN CB  HB3  sing N N 111 
GLN CG  CD   sing N N 112 
GLN CG  HG2  sing N N 113 
GLN CG  HG3  sing N N 114 
GLN CD  OE1  doub N N 115 
GLN CD  NE2  sing N N 116 
GLN NE2 HE21 sing N N 117 
GLN NE2 HE22 sing N N 118 
GLN OXT HXT  sing N N 119 
GLU N   CA   sing N N 120 
GLU N   H    sing N N 121 
GLU N   H2   sing N N 122 
GLU CA  C    sing N N 123 
GLU CA  CB   sing N N 124 
GLU CA  HA   sing N N 125 
GLU C   O    doub N N 126 
GLU C   OXT  sing N N 127 
GLU CB  CG   sing N N 128 
GLU CB  HB2  sing N N 129 
GLU CB  HB3  sing N N 130 
GLU CG  CD   sing N N 131 
GLU CG  HG2  sing N N 132 
GLU CG  HG3  sing N N 133 
GLU CD  OE1  doub N N 134 
GLU CD  OE2  sing N N 135 
GLU OE2 HE2  sing N N 136 
GLU OXT HXT  sing N N 137 
GLY N   CA   sing N N 138 
GLY N   H    sing N N 139 
GLY N   H2   sing N N 140 
GLY CA  C    sing N N 141 
GLY CA  HA2  sing N N 142 
GLY CA  HA3  sing N N 143 
GLY C   O    doub N N 144 
GLY C   OXT  sing N N 145 
GLY OXT HXT  sing N N 146 
HIS N   CA   sing N N 147 
HIS N   H    sing N N 148 
HIS N   H2   sing N N 149 
HIS CA  C    sing N N 150 
HIS CA  CB   sing N N 151 
HIS CA  HA   sing N N 152 
HIS C   O    doub N N 153 
HIS C   OXT  sing N N 154 
HIS CB  CG   sing N N 155 
HIS CB  HB2  sing N N 156 
HIS CB  HB3  sing N N 157 
HIS CG  ND1  sing Y N 158 
HIS CG  CD2  doub Y N 159 
HIS ND1 CE1  doub Y N 160 
HIS ND1 HD1  sing N N 161 
HIS CD2 NE2  sing Y N 162 
HIS CD2 HD2  sing N N 163 
HIS CE1 NE2  sing Y N 164 
HIS CE1 HE1  sing N N 165 
HIS NE2 HE2  sing N N 166 
HIS OXT HXT  sing N N 167 
HOH O   H1   sing N N 168 
HOH O   H2   sing N N 169 
ILE N   CA   sing N N 170 
ILE N   H    sing N N 171 
ILE N   H2   sing N N 172 
ILE CA  C    sing N N 173 
ILE CA  CB   sing N N 174 
ILE CA  HA   sing N N 175 
ILE C   O    doub N N 176 
ILE C   OXT  sing N N 177 
ILE CB  CG1  sing N N 178 
ILE CB  CG2  sing N N 179 
ILE CB  HB   sing N N 180 
ILE CG1 CD1  sing N N 181 
ILE CG1 HG12 sing N N 182 
ILE CG1 HG13 sing N N 183 
ILE CG2 HG21 sing N N 184 
ILE CG2 HG22 sing N N 185 
ILE CG2 HG23 sing N N 186 
ILE CD1 HD11 sing N N 187 
ILE CD1 HD12 sing N N 188 
ILE CD1 HD13 sing N N 189 
ILE OXT HXT  sing N N 190 
K5O O2  S1   doub N N 191 
K5O O1  S1   doub N N 192 
K5O C19 S1   sing N N 193 
K5O S1  N7   sing N N 194 
K5O N7  C17  sing N N 195 
K5O N7  C16  sing N N 196 
K5O C17 C18  sing N N 197 
K5O C24 C23  sing N N 198 
K5O C1  N1   sing N N 199 
K5O C16 C15  sing N N 200 
K5O C18 N6   sing N N 201 
K5O C21 C22  sing Y N 202 
K5O C21 C20  doub Y N 203 
K5O C23 C22  doub Y N 204 
K5O C23 C8   sing Y N 205 
K5O N1  C2   sing N N 206 
K5O C7  C8   sing N N 207 
K5O C7  N4   sing N N 208 
K5O C22 C11  sing Y N 209 
K5O C15 N6   sing N N 210 
K5O C26 N4   sing N N 211 
K5O C26 C27  sing N N 212 
K5O N8  C25  trip N N 213 
K5O C8  C9   doub Y N 214 
K5O C25 C20  sing N N 215 
K5O C20 N5   sing Y N 216 
K5O N6  C13  sing N N 217 
K5O N4  C6   sing N N 218 
K5O C2  N2   doub Y N 219 
K5O C2  N9   sing Y N 220 
K5O C11 N5   sing Y N 221 
K5O C11 C10  doub Y N 222 
K5O C27 C4   sing N N 223 
K5O N2  C3   sing Y N 224 
K5O N5  C12  sing N N 225 
K5O C9  C10  sing Y N 226 
K5O C6  C5   sing N N 227 
K5O C4  C5   sing N N 228 
K5O C4  N3   sing N N 229 
K5O C13 C12  sing N N 230 
K5O C13 C14  sing N N 231 
K5O N9  C33  doub Y N 232 
K5O C3  N3   sing N N 233 
K5O C3  C28  doub Y N 234 
K5O C33 C28  sing Y N 235 
K5O C33 S2   sing Y N 236 
K5O C28 C29  sing Y N 237 
K5O S2  C30  sing Y N 238 
K5O C29 C30  doub Y N 239 
K5O C30 C31  sing N N 240 
K5O F1  C32  sing N N 241 
K5O F2  C32  sing N N 242 
K5O C31 C32  sing N N 243 
K5O C32 F3   sing N N 244 
K5O C1  H1   sing N N 245 
K5O C1  H2   sing N N 246 
K5O C1  H3   sing N N 247 
K5O N1  H4   sing N N 248 
K5O N3  H5   sing N N 249 
K5O C4  H6   sing N N 250 
K5O C5  H7   sing N N 251 
K5O C5  H8   sing N N 252 
K5O C6  H9   sing N N 253 
K5O C6  H10  sing N N 254 
K5O C7  H12  sing N N 255 
K5O C7  H13  sing N N 256 
K5O C9  H14  sing N N 257 
K5O C10 H15  sing N N 258 
K5O C12 H16  sing N N 259 
K5O C12 H17  sing N N 260 
K5O C13 H18  sing N N 261 
K5O C14 H19  sing N N 262 
K5O C14 H20  sing N N 263 
K5O C14 H21  sing N N 264 
K5O C15 H23  sing N N 265 
K5O C15 H24  sing N N 266 
K5O C16 H25  sing N N 267 
K5O C16 H26  sing N N 268 
K5O C17 H27  sing N N 269 
K5O C17 H28  sing N N 270 
K5O C18 H29  sing N N 271 
K5O C18 H30  sing N N 272 
K5O C19 H31  sing N N 273 
K5O C19 H32  sing N N 274 
K5O C19 H33  sing N N 275 
K5O C21 H34  sing N N 276 
K5O C24 H35  sing N N 277 
K5O C24 H36  sing N N 278 
K5O C24 H37  sing N N 279 
K5O C26 H38  sing N N 280 
K5O C26 H39  sing N N 281 
K5O C27 H40  sing N N 282 
K5O C27 H41  sing N N 283 
K5O C29 H42  sing N N 284 
K5O C31 H43  sing N N 285 
K5O C31 H44  sing N N 286 
LEU N   CA   sing N N 287 
LEU N   H    sing N N 288 
LEU N   H2   sing N N 289 
LEU CA  C    sing N N 290 
LEU CA  CB   sing N N 291 
LEU CA  HA   sing N N 292 
LEU C   O    doub N N 293 
LEU C   OXT  sing N N 294 
LEU CB  CG   sing N N 295 
LEU CB  HB2  sing N N 296 
LEU CB  HB3  sing N N 297 
LEU CG  CD1  sing N N 298 
LEU CG  CD2  sing N N 299 
LEU CG  HG   sing N N 300 
LEU CD1 HD11 sing N N 301 
LEU CD1 HD12 sing N N 302 
LEU CD1 HD13 sing N N 303 
LEU CD2 HD21 sing N N 304 
LEU CD2 HD22 sing N N 305 
LEU CD2 HD23 sing N N 306 
LEU OXT HXT  sing N N 307 
LYS N   CA   sing N N 308 
LYS N   H    sing N N 309 
LYS N   H2   sing N N 310 
LYS CA  C    sing N N 311 
LYS CA  CB   sing N N 312 
LYS CA  HA   sing N N 313 
LYS C   O    doub N N 314 
LYS C   OXT  sing N N 315 
LYS CB  CG   sing N N 316 
LYS CB  HB2  sing N N 317 
LYS CB  HB3  sing N N 318 
LYS CG  CD   sing N N 319 
LYS CG  HG2  sing N N 320 
LYS CG  HG3  sing N N 321 
LYS CD  CE   sing N N 322 
LYS CD  HD2  sing N N 323 
LYS CD  HD3  sing N N 324 
LYS CE  NZ   sing N N 325 
LYS CE  HE2  sing N N 326 
LYS CE  HE3  sing N N 327 
LYS NZ  HZ1  sing N N 328 
LYS NZ  HZ2  sing N N 329 
LYS NZ  HZ3  sing N N 330 
LYS OXT HXT  sing N N 331 
MET N   CA   sing N N 332 
MET N   H    sing N N 333 
MET N   H2   sing N N 334 
MET CA  C    sing N N 335 
MET CA  CB   sing N N 336 
MET CA  HA   sing N N 337 
MET C   O    doub N N 338 
MET C   OXT  sing N N 339 
MET CB  CG   sing N N 340 
MET CB  HB2  sing N N 341 
MET CB  HB3  sing N N 342 
MET CG  SD   sing N N 343 
MET CG  HG2  sing N N 344 
MET CG  HG3  sing N N 345 
MET SD  CE   sing N N 346 
MET CE  HE1  sing N N 347 
MET CE  HE2  sing N N 348 
MET CE  HE3  sing N N 349 
MET OXT HXT  sing N N 350 
PEG C1  O1   sing N N 351 
PEG C1  C2   sing N N 352 
PEG C1  H11  sing N N 353 
PEG C1  H12  sing N N 354 
PEG O1  HO1  sing N N 355 
PEG C2  O2   sing N N 356 
PEG C2  H21  sing N N 357 
PEG C2  H22  sing N N 358 
PEG O2  C3   sing N N 359 
PEG C3  C4   sing N N 360 
PEG C3  H31  sing N N 361 
PEG C3  H32  sing N N 362 
PEG C4  O4   sing N N 363 
PEG C4  H41  sing N N 364 
PEG C4  H42  sing N N 365 
PEG O4  HO4  sing N N 366 
PG4 O1  C1   sing N N 367 
PG4 O1  HO1  sing N N 368 
PG4 C1  C2   sing N N 369 
PG4 C1  H11  sing N N 370 
PG4 C1  H12  sing N N 371 
PG4 C2  O2   sing N N 372 
PG4 C2  H21  sing N N 373 
PG4 C2  H22  sing N N 374 
PG4 O2  C3   sing N N 375 
PG4 C3  C4   sing N N 376 
PG4 C3  H31  sing N N 377 
PG4 C3  H32  sing N N 378 
PG4 C4  O3   sing N N 379 
PG4 C4  H41  sing N N 380 
PG4 C4  H42  sing N N 381 
PG4 O3  C5   sing N N 382 
PG4 C5  C6   sing N N 383 
PG4 C5  H51  sing N N 384 
PG4 C5  H52  sing N N 385 
PG4 C6  O4   sing N N 386 
PG4 C6  H61  sing N N 387 
PG4 C6  H62  sing N N 388 
PG4 O4  C7   sing N N 389 
PG4 C7  C8   sing N N 390 
PG4 C7  H71  sing N N 391 
PG4 C7  H72  sing N N 392 
PG4 C8  O5   sing N N 393 
PG4 C8  H81  sing N N 394 
PG4 C8  H82  sing N N 395 
PG4 O5  HO5  sing N N 396 
PHE N   CA   sing N N 397 
PHE N   H    sing N N 398 
PHE N   H2   sing N N 399 
PHE CA  C    sing N N 400 
PHE CA  CB   sing N N 401 
PHE CA  HA   sing N N 402 
PHE C   O    doub N N 403 
PHE C   OXT  sing N N 404 
PHE CB  CG   sing N N 405 
PHE CB  HB2  sing N N 406 
PHE CB  HB3  sing N N 407 
PHE CG  CD1  doub Y N 408 
PHE CG  CD2  sing Y N 409 
PHE CD1 CE1  sing Y N 410 
PHE CD1 HD1  sing N N 411 
PHE CD2 CE2  doub Y N 412 
PHE CD2 HD2  sing N N 413 
PHE CE1 CZ   doub Y N 414 
PHE CE1 HE1  sing N N 415 
PHE CE2 CZ   sing Y N 416 
PHE CE2 HE2  sing N N 417 
PHE CZ  HZ   sing N N 418 
PHE OXT HXT  sing N N 419 
PRO N   CA   sing N N 420 
PRO N   CD   sing N N 421 
PRO N   H    sing N N 422 
PRO CA  C    sing N N 423 
PRO CA  CB   sing N N 424 
PRO CA  HA   sing N N 425 
PRO C   O    doub N N 426 
PRO C   OXT  sing N N 427 
PRO CB  CG   sing N N 428 
PRO CB  HB2  sing N N 429 
PRO CB  HB3  sing N N 430 
PRO CG  CD   sing N N 431 
PRO CG  HG2  sing N N 432 
PRO CG  HG3  sing N N 433 
PRO CD  HD2  sing N N 434 
PRO CD  HD3  sing N N 435 
PRO OXT HXT  sing N N 436 
SER N   CA   sing N N 437 
SER N   H    sing N N 438 
SER N   H2   sing N N 439 
SER CA  C    sing N N 440 
SER CA  CB   sing N N 441 
SER CA  HA   sing N N 442 
SER C   O    doub N N 443 
SER C   OXT  sing N N 444 
SER CB  OG   sing N N 445 
SER CB  HB2  sing N N 446 
SER CB  HB3  sing N N 447 
SER OG  HG   sing N N 448 
SER OXT HXT  sing N N 449 
SO4 S   O1   doub N N 450 
SO4 S   O2   doub N N 451 
SO4 S   O3   sing N N 452 
SO4 S   O4   sing N N 453 
THR N   CA   sing N N 454 
THR N   H    sing N N 455 
THR N   H2   sing N N 456 
THR CA  C    sing N N 457 
THR CA  CB   sing N N 458 
THR CA  HA   sing N N 459 
THR C   O    doub N N 460 
THR C   OXT  sing N N 461 
THR CB  OG1  sing N N 462 
THR CB  CG2  sing N N 463 
THR CB  HB   sing N N 464 
THR OG1 HG1  sing N N 465 
THR CG2 HG21 sing N N 466 
THR CG2 HG22 sing N N 467 
THR CG2 HG23 sing N N 468 
THR OXT HXT  sing N N 469 
TRP N   CA   sing N N 470 
TRP N   H    sing N N 471 
TRP N   H2   sing N N 472 
TRP CA  C    sing N N 473 
TRP CA  CB   sing N N 474 
TRP CA  HA   sing N N 475 
TRP C   O    doub N N 476 
TRP C   OXT  sing N N 477 
TRP CB  CG   sing N N 478 
TRP CB  HB2  sing N N 479 
TRP CB  HB3  sing N N 480 
TRP CG  CD1  doub Y N 481 
TRP CG  CD2  sing Y N 482 
TRP CD1 NE1  sing Y N 483 
TRP CD1 HD1  sing N N 484 
TRP CD2 CE2  doub Y N 485 
TRP CD2 CE3  sing Y N 486 
TRP NE1 CE2  sing Y N 487 
TRP NE1 HE1  sing N N 488 
TRP CE2 CZ2  sing Y N 489 
TRP CE3 CZ3  doub Y N 490 
TRP CE3 HE3  sing N N 491 
TRP CZ2 CH2  doub Y N 492 
TRP CZ2 HZ2  sing N N 493 
TRP CZ3 CH2  sing Y N 494 
TRP CZ3 HZ3  sing N N 495 
TRP CH2 HH2  sing N N 496 
TRP OXT HXT  sing N N 497 
TYR N   CA   sing N N 498 
TYR N   H    sing N N 499 
TYR N   H2   sing N N 500 
TYR CA  C    sing N N 501 
TYR CA  CB   sing N N 502 
TYR CA  HA   sing N N 503 
TYR C   O    doub N N 504 
TYR C   OXT  sing N N 505 
TYR CB  CG   sing N N 506 
TYR CB  HB2  sing N N 507 
TYR CB  HB3  sing N N 508 
TYR CG  CD1  doub Y N 509 
TYR CG  CD2  sing Y N 510 
TYR CD1 CE1  sing Y N 511 
TYR CD1 HD1  sing N N 512 
TYR CD2 CE2  doub Y N 513 
TYR CD2 HD2  sing N N 514 
TYR CE1 CZ   doub Y N 515 
TYR CE1 HE1  sing N N 516 
TYR CE2 CZ   sing Y N 517 
TYR CE2 HE2  sing N N 518 
TYR CZ  OH   sing N N 519 
TYR OH  HH   sing N N 520 
TYR OXT HXT  sing N N 521 
VAL N   CA   sing N N 522 
VAL N   H    sing N N 523 
VAL N   H2   sing N N 524 
VAL CA  C    sing N N 525 
VAL CA  CB   sing N N 526 
VAL CA  HA   sing N N 527 
VAL C   O    doub N N 528 
VAL C   OXT  sing N N 529 
VAL CB  CG1  sing N N 530 
VAL CB  CG2  sing N N 531 
VAL CB  HB   sing N N 532 
VAL CG1 HG11 sing N N 533 
VAL CG1 HG12 sing N N 534 
VAL CG1 HG13 sing N N 535 
VAL CG2 HG21 sing N N 536 
VAL CG2 HG22 sing N N 537 
VAL CG2 HG23 sing N N 538 
VAL OXT HXT  sing N N 539 
# 
_pdbx_audit_support.funding_organization   'Leukemia & Lymphoma Society' 
_pdbx_audit_support.country                'United States' 
_pdbx_audit_support.grant_number           6485-16 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   4GPQ 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    8VA6 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.020663 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.012472 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.008005 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.pdbx_scat_Z 
_atom_type.pdbx_N_electrons 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
C 6  6  2.3103  20.8439 1.0201 10.2075 1.5888 0.5687  0.8651 51.6512 0.2156   
F 9  9  3.5395  10.2825 2.6414 4.2944  1.5171 0.2615  1.0244 26.1476 0.2776   
H 1  1  0.4930  10.5109 0.3229 26.1257 0.1402 3.1424  0.0408 57.7997 0.0030   
N 7  7  12.2220 0.0057  3.1346 9.8933  2.0141 28.9975 1.1672 0.5826  -11.5379 
O 8  8  3.0487  13.2771 2.2870 5.7011  1.5464 0.3239  0.8671 32.9089 0.2508   
S 16 16 6.9054  1.4679  5.2035 22.2151 1.4379 0.2536  1.5863 56.1720 0.8669   
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
_atom_site.calc_flag 
ATOM   1    C C    . GLY A 1 7   ? 8.534   -17.505 1.321   1.000 41.285 0 2    GLY A C    1 ? 
ATOM   2    O O    . GLY A 1 7   ? 8.674   -17.886 0.155   1.000 45.784 0 2    GLY A O    1 ? 
ATOM   3    N N    . LEU A 1 8   ? 9.484   -16.876 2.031   1.000 45.000 0 3    LEU A N    1 ? 
ATOM   4    C CA   . LEU A 1 8   ? 10.858  -16.684 1.574   1.000 37.563 0 3    LEU A CA   1 ? 
ATOM   5    C C    . LEU A 1 8   ? 11.565  -18.029 1.507   1.000 37.923 0 3    LEU A C    1 ? 
ATOM   6    O O    . LEU A 1 8   ? 11.296  -18.887 2.339   1.000 38.157 0 3    LEU A O    1 ? 
ATOM   7    C CB   . LEU A 1 8   ? 11.612  -15.810 2.573   1.000 34.689 0 3    LEU A CB   1 ? 
ATOM   8    C CG   . LEU A 1 8   ? 11.241  -14.334 2.641   1.000 35.650 0 3    LEU A CG   1 ? 
ATOM   9    C CD1  . LEU A 1 8   ? 11.722  -13.727 3.945   1.000 35.508 0 3    LEU A CD1  1 ? 
ATOM   10   C CD2  . LEU A 1 8   ? 11.883  -13.684 1.424   1.000 33.092 0 3    LEU A CD2  1 ? 
ATOM   11   H H    . LEU A 1 8   ? 9.255   -16.547 2.852   1.000 42.206 0 3    LEU A H    1 c 
ATOM   12   H HA   . LEU A 1 8   ? 10.850  -16.257 0.680   1.000 38.338 0 3    LEU A HA   1 c 
ATOM   13   H HB2  . LEU A 1 8   ? 11.488  -16.199 3.469   1.000 35.649 0 3    LEU A HB2  1 c 
ATOM   14   H HB3  . LEU A 1 8   ? 12.574  -15.877 2.371   1.000 35.552 0 3    LEU A HB3  1 c 
ATOM   15   H HG   . LEU A 1 8   ? 10.255  -14.246 2.579   1.000 34.961 0 3    LEU A HG   1 c 
ATOM   16   H HD11 . LEU A 1 8   ? 11.290  -14.176 4.691   1.000 35.551 0 3    LEU A HD11 1 c 
ATOM   17   H HD12 . LEU A 1 8   ? 11.499  -12.782 3.965   1.000 35.550 0 3    LEU A HD12 1 c 
ATOM   18   H HD13 . LEU A 1 8   ? 12.685  -13.834 4.018   1.000 35.550 0 3    LEU A HD13 1 c 
ATOM   19   H HD21 . LEU A 1 8   ? 11.532  -14.090 0.614   1.000 33.879 0 3    LEU A HD21 1 c 
ATOM   20   H HD22 . LEU A 1 8   ? 12.846  -13.809 1.458   1.000 33.851 0 3    LEU A HD22 1 c 
ATOM   21   H HD23 . LEU A 1 8   ? 11.681  -12.733 1.421   1.000 33.842 0 3    LEU A HD23 1 c 
ATOM   22   N N    . LYS A 1 9   ? 12.525  -18.149 0.598   1.000 33.545 0 4    LYS A N    1 ? 
ATOM   23   C CA   . LYS A 1 9   ? 13.356  -19.326 0.477   1.000 39.455 0 4    LYS A CA   1 ? 
ATOM   24   C C    . LYS A 1 9   ? 14.534  -19.245 1.437   1.000 33.343 0 4    LYS A C    1 ? 
ATOM   25   O O    . LYS A 1 9   ? 14.966  -18.167 1.810   1.000 28.727 0 4    LYS A O    1 ? 
ATOM   26   C CB   . LYS A 1 9   ? 13.825  -19.485 -0.980  1.000 42.005 0 4    LYS A CB   1 ? 
ATOM   27   C CG   . LYS A 1 9   ? 12.786  -20.154 -1.876  1.000 51.317 0 4    LYS A CG   1 ? 
ATOM   28   C CD   . LYS A 1 9   ? 13.350  -20.664 -3.195  1.000 62.358 0 4    LYS A CD   1 ? 
ATOM   29   C CE   . LYS A 1 9   ? 12.286  -21.381 -3.979  1.000 71.095 0 4    LYS A CE   1 ? 
ATOM   30   N NZ   . LYS A 1 9   ? 12.666  -21.565 -5.382  1.000 76.013 0 4    LYS A NZ   1 ? 
ATOM   31   H H    . LYS A 1 9   ? 12.672  -17.454 0.024   1.000 35.935 0 4    LYS A H    1 c 
ATOM   32   H HA   . LYS A 1 9   ? 12.811  -20.118 0.717   1.000 37.583 0 4    LYS A HA   1 c 
ATOM   33   H HB2  . LYS A 1 9   ? 14.037  -18.601 -1.349  1.000 43.284 0 4    LYS A HB2  1 c 
ATOM   34   H HB3  . LYS A 1 9   ? 14.645  -20.023 -0.996  1.000 43.250 0 4    LYS A HB3  1 c 
ATOM   35   H HG2  . LYS A 1 9   ? 12.389  -20.907 -1.387  1.000 51.138 0 4    LYS A HG2  1 c 
ATOM   36   H HG3  . LYS A 1 9   ? 12.071  -19.506 -2.062  1.000 51.227 0 4    LYS A HG3  1 c 
ATOM   37   H HD2  . LYS A 1 9   ? 13.687  -19.907 -3.722  1.000 61.572 0 4    LYS A HD2  1 c 
ATOM   38   H HD3  . LYS A 1 9   ? 14.094  -21.279 -3.018  1.000 61.512 0 4    LYS A HD3  1 c 
ATOM   39   H HE2  . LYS A 1 9   ? 12.122  -22.253 -3.579  1.000 70.078 0 4    LYS A HE2  1 c 
ATOM   40   H HE3  . LYS A 1 9   ? 11.458  -20.871 -3.942  1.000 69.980 0 4    LYS A HE3  1 c 
ATOM   41   H HZ1  . LYS A 1 9   ? 13.427  -22.054 -5.432  1.000 74.442 0 4    LYS A HZ1  1 c 
ATOM   42   H HZ2  . LYS A 1 9   ? 12.805  -20.758 -5.770  1.000 74.369 0 4    LYS A HZ2  1 c 
ATOM   43   H HZ3  . LYS A 1 9   ? 12.004  -21.998 -5.824  1.000 74.442 0 4    LYS A HZ3  1 c 
ATOM   44   N N    . ALA A 1 10  ? 15.068  -20.406 1.850   1.000 31.730 0 5    ALA A N    1 ? 
ATOM   45   C CA   . ALA A 1 10  ? 16.165  -20.420 2.802   1.000 27.007 0 5    ALA A CA   1 ? 
ATOM   46   C C    . ALA A 1 10  ? 17.320  -19.524 2.373   1.000 28.027 0 5    ALA A C    1 ? 
ATOM   47   O O    . ALA A 1 10  ? 17.904  -18.848 3.201   1.000 27.336 0 5    ALA A O    1 ? 
ATOM   48   C CB   . ALA A 1 10  ? 16.667  -21.861 3.021   1.000 27.776 0 5    ALA A CB   1 ? 
ATOM   49   H H    . ALA A 1 10  ? 14.742  -21.199 1.532   1.000 31.035 0 5    ALA A H    1 c 
ATOM   50   H HA   . ALA A 1 10  ? 15.817  -20.070 3.669   1.000 28.201 0 5    ALA A HA   1 c 
ATOM   51   H HB1  . ALA A 1 10  ? 15.943  -22.410 3.367   1.000 27.550 0 5    ALA A HB1  1 c 
ATOM   52   H HB2  . ALA A 1 10  ? 16.975  -22.232 2.177   1.000 27.550 0 5    ALA A HB2  1 c 
ATOM   53   H HB3  . ALA A 1 10  ? 17.401  -21.859 3.657   1.000 27.550 0 5    ALA A HB3  1 c 
ATOM   54   N N    . ALA A 1 11  ? 17.689  -19.540 1.082   1.000 28.708 0 6    ALA A N    1 ? 
ATOM   55   C CA   . ALA A 1 11  ? 18.846  -18.817 0.567   1.000 31.845 0 6    ALA A CA   1 ? 
ATOM   56   C C    . ALA A 1 11  ? 18.661  -17.301 0.634   1.000 32.468 0 6    ALA A C    1 ? 
ATOM   57   O O    . ALA A 1 11  ? 19.648  -16.571 0.722   1.000 33.989 0 6    ALA A O    1 ? 
ATOM   58   C CB   . ALA A 1 11  ? 19.146  -19.235 -0.869  1.000 33.273 0 6    ALA A CB   1 ? 
ATOM   59   H H    . ALA A 1 11  ? 17.192  -20.032 0.493   1.000 29.267 0 6    ALA A H    1 c 
ATOM   60   H HA   . ALA A 1 11  ? 19.629  -19.053 1.138   1.000 31.546 0 6    ALA A HA   1 c 
ATOM   61   H HB1  . ALA A 1 11  ? 19.335  -20.188 -0.899  1.000 32.846 0 6    ALA A HB1  1 c 
ATOM   62   H HB2  . ALA A 1 11  ? 18.379  -19.042 -1.433  1.000 32.846 0 6    ALA A HB2  1 c 
ATOM   63   H HB3  . ALA A 1 11  ? 19.918  -18.745 -1.198  1.000 32.844 0 6    ALA A HB3  1 c 
ATOM   64   N N    . GLN A 1 12  ? 17.399  -16.851 0.605   1.000 28.239 0 7    GLN A N    1 ? 
ATOM   65   C CA   . GLN A 1 12  ? 17.103  -15.445 0.762   1.000 29.480 0 7    GLN A CA   1 ? 
ATOM   66   C C    . GLN A 1 12  ? 17.291  -14.977 2.197   1.000 29.504 0 7    GLN A C    1 ? 
ATOM   67   O O    . GLN A 1 12  ? 17.276  -13.773 2.423   1.000 32.289 0 7    GLN A O    1 ? 
ATOM   68   C CB   . GLN A 1 12  ? 15.668  -15.121 0.337   1.000 28.381 0 7    GLN A CB   1 ? 
ATOM   69   C CG   . GLN A 1 12  ? 15.305  -15.624 -1.058  1.000 28.764 0 7    GLN A CG   1 ? 
ATOM   70   C CD   . GLN A 1 12  ? 13.908  -15.247 -1.474  1.000 30.701 0 7    GLN A CD   1 ? 
ATOM   71   O OE1  . GLN A 1 12  ? 12.948  -16.006 -1.271  1.000 28.705 0 7    GLN A OE1  1 ? 
ATOM   72   N NE2  . GLN A 1 12  ? 13.786  -14.043 -2.035  1.000 25.633 0 7    GLN A NE2  1 ? 
ATOM   73   H H    . GLN A 1 12  ? 16.709  -17.439 0.487   1.000 29.466 0 7    GLN A H    1 c 
ATOM   74   H HA   . GLN A 1 12  ? 17.720  -14.932 0.182   1.000 29.124 0 7    GLN A HA   1 c 
ATOM   75   H HB2  . GLN A 1 12  ? 15.051  -15.518 0.987   1.000 28.722 0 7    GLN A HB2  1 c 
ATOM   76   H HB3  . GLN A 1 12  ? 15.545  -14.150 0.365   1.000 28.732 0 7    GLN A HB3  1 c 
ATOM   77   H HG2  . GLN A 1 12  ? 15.940  -15.259 -1.709  1.000 29.075 0 7    GLN A HG2  1 c 
ATOM   78   H HG3  . GLN A 1 12  ? 15.383  -16.601 -1.081  1.000 29.104 0 7    GLN A HG3  1 c 
ATOM   79   H HE21 . GLN A 1 12  ? 14.498  -13.528 -2.152  1.000 27.074 0 7    GLN A HE21 1 c 
ATOM   80   H HE22 . GLN A 1 12  ? 12.986  -13.758 -2.288  1.000 26.956 0 7    GLN A HE22 1 c 
ATOM   81   N N    . LYS A 1 13  ? 17.374  -15.882 3.191   1.000 27.902 0 8    LYS A N    1 ? 
ATOM   82   C CA   . LYS A 1 13  ? 17.311  -15.471 4.589   1.000 28.182 0 8    LYS A CA   1 ? 
ATOM   83   C C    . LYS A 1 13  ? 18.687  -15.439 5.273   1.000 27.212 0 8    LYS A C    1 ? 
ATOM   84   O O    . LYS A 1 13  ? 18.779  -14.915 6.384   1.000 27.233 0 8    LYS A O    1 ? 
ATOM   85   C CB   . LYS A 1 13  ? 16.444  -16.421 5.418   1.000 28.525 0 8    LYS A CB   1 ? 
ATOM   86   C CG   . LYS A 1 13  ? 15.025  -16.522 4.996   1.000 27.952 0 8    LYS A CG   1 ? 
ATOM   87   C CD   . LYS A 1 13  ? 14.396  -17.707 5.714   1.000 32.532 0 8    LYS A CD   1 ? 
ATOM   88   C CE   . LYS A 1 13  ? 12.974  -17.916 5.388   1.000 38.531 0 8    LYS A CE   1 ? 
ATOM   89   N NZ   . LYS A 1 13  ? 12.327  -18.846 6.319   1.000 42.128 0 8    LYS A NZ   1 ? 
ATOM   90   H H    . LYS A 1 13  ? 17.466  -16.770 2.996   1.000 28.360 0 8    LYS A H    1 c 
ATOM   91   H HA   . LYS A 1 13  ? 16.914  -14.564 4.635   1.000 28.044 0 8    LYS A HA   1 c 
ATOM   92   H HB2  . LYS A 1 13  ? 16.842  -17.316 5.380   1.000 28.367 0 8    LYS A HB2  1 c 
ATOM   93   H HB3  . LYS A 1 13  ? 16.465  -16.128 6.353   1.000 28.370 0 8    LYS A HB3  1 c 
ATOM   94   H HG2  . LYS A 1 13  ? 14.551  -15.696 5.232   1.000 29.057 0 8    LYS A HG2  1 c 
ATOM   95   H HG3  . LYS A 1 13  ? 14.979  -16.655 4.024   1.000 29.050 0 8    LYS A HG3  1 c 
ATOM   96   H HD2  . LYS A 1 13  ? 14.895  -18.520 5.480   1.000 32.695 0 8    LYS A HD2  1 c 
ATOM   97   H HD3  . LYS A 1 13  ? 14.484  -17.572 6.681   1.000 32.767 0 8    LYS A HD3  1 c 
ATOM   98   H HE2  . LYS A 1 13  ? 12.507  -17.062 5.421   1.000 37.812 0 8    LYS A HE2  1 c 
ATOM   99   H HE3  . LYS A 1 13  ? 12.897  -18.269 4.484   1.000 37.824 0 8    LYS A HE3  1 c 
ATOM   100  H HZ1  . LYS A 1 13  ? 12.551  -18.644 7.174   1.000 40.863 0 8    LYS A HZ1  1 c 
ATOM   101  H HZ2  . LYS A 1 13  ? 12.586  -19.693 6.135   1.000 40.957 0 8    LYS A HZ2  1 c 
ATOM   102  H HZ3  . LYS A 1 13  ? 11.427  -18.788 6.229   1.000 40.958 0 8    LYS A HZ3  1 c 
ATOM   103  N N    . THR A 1 14  ? 19.749  -15.910 4.594   1.000 27.110 0 9    THR A N    1 ? 
ATOM   104  C CA   . THR A 1 14  ? 21.057  -16.132 5.215   1.000 30.454 0 9    THR A CA   1 ? 
ATOM   105  C C    . THR A 1 14  ? 21.798  -14.831 5.553   1.000 29.158 0 9    THR A C    1 ? 
ATOM   106  O O    . THR A 1 14  ? 22.615  -14.808 6.469   1.000 34.218 0 9    THR A O    1 ? 
ATOM   107  C CB   . THR A 1 14  ? 21.926  -17.031 4.333   1.000 34.991 0 9    THR A CB   1 ? 
ATOM   108  O OG1  . THR A 1 14  ? 22.104  -16.394 3.063   1.000 36.740 0 9    THR A OG1  1 ? 
ATOM   109  C CG2  . THR A 1 14  ? 21.316  -18.401 4.123   1.000 35.303 0 9    THR A CG2  1 ? 
ATOM   110  H H    . THR A 1 14  ? 19.657  -16.095 3.704   1.000 27.981 0 9    THR A H    1 c 
ATOM   111  H HA   . THR A 1 14  ? 20.900  -16.611 6.058   1.000 30.288 0 9    THR A HA   1 c 
ATOM   112  H HB   . THR A 1 14  ? 22.808  -17.145 4.760   1.000 34.472 0 9    THR A HB   1 c 
ATOM   113  H HG1  . THR A 1 14  ? 21.337  -16.273 2.687   0.000 36.520 0 9    THR A HG1  1 c 
ATOM   114  H HG21 . THR A 1 14  ? 21.931  -18.956 3.614   1.000 35.173 0 9    THR A HG21 1 c 
ATOM   115  H HG22 . THR A 1 14  ? 20.480  -18.315 3.636   1.000 35.057 0 9    THR A HG22 1 c 
ATOM   116  H HG23 . THR A 1 14  ? 21.146  -18.816 4.986   1.000 35.173 0 9    THR A HG23 1 c 
ATOM   117  N N    . LEU A 1 15  ? 21.511  -13.711 4.871   1.000 28.980 0 10   LEU A N    1 ? 
ATOM   118  C CA   . LEU A 1 15  ? 22.191  -12.459 5.186   1.000 30.923 0 10   LEU A CA   1 ? 
ATOM   119  C C    . LEU A 1 15  ? 21.563  -11.724 6.365   1.000 30.390 0 10   LEU A C    1 ? 
ATOM   120  O O    . LEU A 1 15  ? 22.167  -10.780 6.892   1.000 32.141 0 10   LEU A O    1 ? 
ATOM   121  C CB   . LEU A 1 15  ? 22.267  -11.536 3.974   1.000 31.687 0 10   LEU A CB   1 ? 
ATOM   122  C CG   . LEU A 1 15  ? 23.168  -12.038 2.843   1.000 34.224 0 10   LEU A CG   1 ? 
ATOM   123  C CD1  . LEU A 1 15  ? 22.857  -11.236 1.572   1.000 30.672 0 10   LEU A CD1  1 ? 
ATOM   124  C CD2  . LEU A 1 15  ? 24.636  -11.861 3.201   1.000 38.630 0 10   LEU A CD2  1 ? 
ATOM   125  H H    . LEU A 1 15  ? 20.890  -13.725 4.201   1.000 29.444 0 10   LEU A H    1 c 
ATOM   126  H HA   . LEU A 1 15  ? 23.118  -12.688 5.451   1.000 30.658 0 10   LEU A HA   1 c 
ATOM   127  H HB2  . LEU A 1 15  ? 21.357  -11.409 3.621   1.000 32.066 0 10   LEU A HB2  1 c 
ATOM   128  H HB3  . LEU A 1 15  ? 22.601  -10.659 4.273   1.000 32.118 0 10   LEU A HB3  1 c 
ATOM   129  H HG   . LEU A 1 15  ? 22.982  -12.998 2.681   1.000 33.798 0 10   LEU A HG   1 c 
ATOM   130  H HD11 . LEU A 1 15  ? 21.929  -11.375 1.319   1.000 31.674 0 10   LEU A HD11 1 c 
ATOM   131  H HD12 . LEU A 1 15  ? 23.436  -11.533 0.850   1.000 31.672 0 10   LEU A HD12 1 c 
ATOM   132  H HD13 . LEU A 1 15  ? 23.008  -10.290 1.738   1.000 31.672 0 10   LEU A HD13 1 c 
ATOM   133  H HD21 . LEU A 1 15  ? 24.852  -12.412 3.972   1.000 37.210 0 10   LEU A HD21 1 c 
ATOM   134  H HD22 . LEU A 1 15  ? 24.810  -10.928 3.411   1.000 37.222 0 10   LEU A HD22 1 c 
ATOM   135  H HD23 . LEU A 1 15  ? 25.188  -12.130 2.448   1.000 37.251 0 10   LEU A HD23 1 c 
ATOM   136  N N    . PHE A 1 16  ? 20.375  -12.147 6.814   1.000 26.203 0 11   PHE A N    1 ? 
ATOM   137  C CA   . PHE A 1 16  ? 19.809  -11.432 7.951   1.000 25.684 0 11   PHE A CA   1 ? 
ATOM   138  C C    . PHE A 1 16  ? 20.553  -11.806 9.235   1.000 29.167 0 11   PHE A C    1 ? 
ATOM   139  O O    . PHE A 1 16  ? 21.057  -12.932 9.361   1.000 28.997 0 11   PHE A O    1 ? 
ATOM   140  C CB   . PHE A 1 16  ? 18.301  -11.729 8.021   1.000 23.611 0 11   PHE A CB   1 ? 
ATOM   141  C CG   . PHE A 1 16  ? 17.525  -11.029 6.920   1.000 23.736 0 11   PHE A CG   1 ? 
ATOM   142  C CD1  . PHE A 1 16  ? 17.399  -11.592 5.642   1.000 25.486 0 11   PHE A CD1  1 ? 
ATOM   143  C CD2  . PHE A 1 16  ? 16.953  -9.787  7.160   1.000 22.242 0 11   PHE A CD2  1 ? 
ATOM   144  C CE1  . PHE A 1 16  ? 16.734  -10.921 4.624   1.000 23.844 0 11   PHE A CE1  1 ? 
ATOM   145  C CE2  . PHE A 1 16  ? 16.287  -9.125  6.141   1.000 22.661 0 11   PHE A CE2  1 ? 
ATOM   146  C CZ   . PHE A 1 16  ? 16.141  -9.706  4.893   1.000 22.510 0 11   PHE A CZ   1 ? 
ATOM   147  H HA   . PHE A 1 16  ? 19.923  -10.460 7.789   1.000 26.033 0 11   PHE A HA   1 c 
ATOM   148  H HB2  . PHE A 1 16  ? 18.166  -12.700 7.946   1.000 24.121 0 11   PHE A HB2  1 c 
ATOM   149  H HB3  . PHE A 1 16  ? 17.961  -11.434 8.894   1.000 24.181 0 11   PHE A HB3  1 c 
ATOM   150  H HD1  . PHE A 1 16  ? 17.797  -12.430 5.465   1.000 24.633 0 11   PHE A HD1  1 c 
ATOM   151  H HD2  . PHE A 1 16  ? 17.037  -9.387  8.010   1.000 22.695 0 11   PHE A HD2  1 c 
ATOM   152  H HE1  . PHE A 1 16  ? 16.638  -11.321 3.775   1.000 23.871 0 11   PHE A HE1  1 c 
ATOM   153  H HE2  . PHE A 1 16  ? 15.885  -8.290  6.315   1.000 22.557 0 11   PHE A HE2  1 c 
ATOM   154  H HZ   . PHE A 1 16  ? 15.682  -9.244  4.210   1.000 22.870 0 11   PHE A HZ   1 c 
ATOM   155  N N    . PRO A 1 17  ? 20.617  -10.916 10.243  1.000 26.320 0 12   PRO A N    1 ? 
ATOM   156  C CA   . PRO A 1 17  ? 20.029  -9.570  10.197  1.000 26.187 0 12   PRO A CA   1 ? 
ATOM   157  C C    . PRO A 1 17  ? 20.854  -8.591  9.370   1.000 25.970 0 12   PRO A C    1 ? 
ATOM   158  O O    . PRO A 1 17  ? 22.077  -8.707  9.320   1.000 28.289 0 12   PRO A O    1 ? 
ATOM   159  C CB   . PRO A 1 17  ? 20.024  -9.140  11.661  1.000 27.350 0 12   PRO A CB   1 ? 
ATOM   160  C CG   . PRO A 1 17  ? 21.221  -9.864  12.235  1.000 26.794 0 12   PRO A CG   1 ? 
ATOM   161  C CD   . PRO A 1 17  ? 21.219  -11.198 11.561  1.000 27.764 0 12   PRO A CD   1 ? 
ATOM   162  H HA   . PRO A 1 17  ? 19.102  -9.618  9.856   1.000 26.308 0 12   PRO A HA   1 c 
ATOM   163  H HB2  . PRO A 1 17  ? 20.126  -8.163  11.745  1.000 26.954 0 12   PRO A HB2  1 c 
ATOM   164  H HB3  . PRO A 1 17  ? 19.192  -9.420  12.109  1.000 26.959 0 12   PRO A HB3  1 c 
ATOM   165  H HG2  . PRO A 1 17  ? 22.050  -9.378  12.040  1.000 27.138 0 12   PRO A HG2  1 c 
ATOM   166  H HG3  . PRO A 1 17  ? 21.135  -9.966  13.206  1.000 27.138 0 12   PRO A HG3  1 c 
ATOM   167  H HD2  . PRO A 1 17  ? 22.132  -11.545 11.465  1.000 27.397 0 12   PRO A HD2  1 c 
ATOM   168  H HD3  . PRO A 1 17  ? 20.679  -11.846 12.066  1.000 27.241 0 12   PRO A HD3  1 c 
ATOM   169  N N    . LEU A 1 18  ? 20.193  -7.557  8.823   1.000 22.420 0 13   LEU A N    1 ? 
ATOM   170  C CA   . LEU A 1 18  ? 20.901  -6.515  8.114   1.000 20.570 0 13   LEU A CA   1 ? 
ATOM   171  C C    . LEU A 1 18  ? 21.259  -5.406  9.088   1.000 21.236 0 13   LEU A C    1 ? 
ATOM   172  O O    . LEU A 1 18  ? 20.357  -4.793  9.692   1.000 22.326 0 13   LEU A O    1 ? 
ATOM   173  C CB   . LEU A 1 18  ? 20.058  -5.961  6.955   1.000 20.538 0 13   LEU A CB   1 ? 
ATOM   174  C CG   . LEU A 1 18  ? 19.415  -7.015  6.056   1.000 20.836 0 13   LEU A CG   1 ? 
ATOM   175  C CD1  . LEU A 1 18  ? 18.526  -6.367  5.006   1.000 21.923 0 13   LEU A CD1  1 ? 
ATOM   176  C CD2  . LEU A 1 18  ? 20.407  -7.922  5.394   1.000 23.357 0 13   LEU A CD2  1 ? 
ATOM   177  H H    . LEU A 1 18  ? 19.284  -7.504  8.902   1.000 22.798 0 13   LEU A H    1 c 
ATOM   178  H HA   . LEU A 1 18  ? 21.738  -6.898  7.747   1.000 21.117 0 13   LEU A HA   1 c 
ATOM   179  H HB2  . LEU A 1 18  ? 19.346  -5.396  7.333   1.000 20.644 0 13   LEU A HB2  1 c 
ATOM   180  H HB3  . LEU A 1 18  ? 20.637  -5.388  6.400   1.000 20.619 0 13   LEU A HB3  1 c 
ATOM   181  H HG   . LEU A 1 18  ? 18.831  -7.581  6.624   1.000 21.453 0 13   LEU A HG   1 c 
ATOM   182  H HD11 . LEU A 1 18  ? 17.871  -5.797  5.442   1.000 21.598 0 13   LEU A HD11 1 c 
ATOM   183  H HD12 . LEU A 1 18  ? 18.067  -7.057  4.499   1.000 21.604 0 13   LEU A HD12 1 c 
ATOM   184  H HD13 . LEU A 1 18  ? 19.070  -5.832  4.404   1.000 21.599 0 13   LEU A HD13 1 c 
ATOM   185  H HD21 . LEU A 1 18  ? 20.882  -8.434  6.070   1.000 22.561 0 13   LEU A HD21 1 c 
ATOM   186  H HD22 . LEU A 1 18  ? 21.042  -7.392  4.884   1.000 22.568 0 13   LEU A HD22 1 c 
ATOM   187  H HD23 . LEU A 1 18  ? 19.941  -8.531  4.797   1.000 22.566 0 13   LEU A HD23 1 c 
ATOM   188  N N    . ARG A 1 19  ? 22.567  -5.174  9.302   1.000 21.655 0 14   ARG A N    1 ? 
ATOM   189  C CA   . ARG A 1 19  ? 22.982  -4.269  10.364  1.000 22.755 0 14   ARG A CA   1 ? 
ATOM   190  C C    . ARG A 1 19  ? 23.615  -2.973  9.878   1.000 24.081 0 14   ARG A C    1 ? 
ATOM   191  O O    . ARG A 1 19  ? 24.022  -2.119  10.683  1.000 24.156 0 14   ARG A O    1 ? 
ATOM   192  C CB   . ARG A 1 19  ? 24.033  -4.979  11.240  1.000 22.888 0 14   ARG A CB   1 ? 
ATOM   193  C CG   . ARG A 1 19  ? 23.549  -6.276  11.862  1.000 27.402 0 14   ARG A CG   1 ? 
ATOM   194  C CD   . ARG A 1 19  ? 24.615  -6.776  12.868  1.000 30.111 0 14   ARG A CD   1 ? 
ATOM   195  N NE   . ARG A 1 19  ? 24.174  -7.937  13.657  1.000 34.598 0 14   ARG A NE   1 ? 
ATOM   196  C CZ   . ARG A 1 19  ? 23.360  -7.835  14.705  1.000 36.031 0 14   ARG A CZ   1 ? 
ATOM   197  N NH1  . ARG A 1 19  ? 23.052  -6.638  15.184  1.000 35.581 0 14   ARG A NH1  1 ? 
ATOM   198  N NH2  . ARG A 1 19  ? 22.856  -8.937  15.256  1.000 43.210 0 14   ARG A NH2  1 ? 
ATOM   199  H H    . ARG A 1 19  ? 23.201  -5.586  8.789   1.000 21.800 0 14   ARG A H    1 c 
ATOM   200  H HA   . ARG A 1 19  ? 22.195  -4.049  10.923  1.000 22.814 0 14   ARG A HA   1 c 
ATOM   201  H HB2  . ARG A 1 19  ? 24.824  -5.168  10.692  1.000 23.849 0 14   ARG A HB2  1 c 
ATOM   202  H HB3  . ARG A 1 19  ? 24.308  -4.370  11.959  1.000 23.942 0 14   ARG A HB3  1 c 
ATOM   203  H HG2  . ARG A 1 19  ? 22.699  -6.125  12.330  1.000 26.903 0 14   ARG A HG2  1 c 
ATOM   204  H HG3  . ARG A 1 19  ? 23.416  -6.952  11.162  1.000 26.837 0 14   ARG A HG3  1 c 
ATOM   205  H HD2  . ARG A 1 19  ? 25.422  -7.019  12.370  1.000 30.488 0 14   ARG A HD2  1 c 
ATOM   206  H HD3  . ARG A 1 19  ? 24.852  -6.047  13.475  1.000 30.547 0 14   ARG A HD3  1 c 
ATOM   207  H HE   . ARG A 1 19  ? 24.461  -8.727  13.428  1.000 33.948 0 14   ARG A HE   1 c 
ATOM   208  H HH11 . ARG A 1 19  ? 23.175  -6.473  16.054  1.000 35.667 0 14   ARG A HH11 1 c 
ATOM   209  H HH12 . ARG A 1 19  ? 22.724  -6.011  14.640  1.000 35.498 0 14   ARG A HH12 1 c 
ATOM   210  H HH21 . ARG A 1 19  ? 22.351  -8.873  15.978  1.000 40.788 0 14   ARG A HH21 1 c 
ATOM   211  H HH22 . ARG A 1 19  ? 23.026  -9.728  14.900  1.000 40.732 0 14   ARG A HH22 1 c 
ATOM   212  N N    . SER A 1 20  ? 23.690  -2.816  8.547   1.000 22.237 0 15   SER A N    1 ? 
ATOM   213  C CA   . SER A 1 20  ? 24.382  -1.682  7.965   1.000 19.990 0 15   SER A CA   1 ? 
ATOM   214  C C    . SER A 1 20  ? 23.900  -1.466  6.523   1.000 20.869 0 15   SER A C    1 ? 
ATOM   215  O O    . SER A 1 20  ? 23.260  -2.355  5.981   1.000 19.213 0 15   SER A O    1 ? 
ATOM   216  C CB   . SER A 1 20  ? 25.849  -1.890  7.912   1.000 19.924 0 15   SER A CB   1 ? 
ATOM   217  O OG   . SER A 1 20  ? 26.149  -2.987  7.052   1.000 21.445 0 15   SER A OG   1 ? 
ATOM   218  H H    . SER A 1 20  ? 23.292  -3.423  7.993   1.000 22.110 0 15   SER A H    1 c 
ATOM   219  H HA   . SER A 1 20  ? 24.183  -0.870  8.497   1.000 20.612 0 15   SER A HA   1 c 
ATOM   220  H HB2  . SER A 1 20  ? 26.282  -1.082  7.579   1.000 20.337 0 15   SER A HB2  1 c 
ATOM   221  H HB3  . SER A 1 20  ? 26.185  -2.075  8.809   1.000 20.313 0 15   SER A HB3  1 c 
ATOM   222  H HG   . SER A 1 20  ? 26.987  -3.092  7.031   0.000 21.470 0 15   SER A HG   1 c 
ATOM   223  N N    . ILE A 1 21  ? 24.267  -0.298  5.988   1.000 21.817 0 16   ILE A N    1 ? 
ATOM   224  C CA   . ILE A 1 21  ? 24.066  0.030   4.591   1.000 19.462 0 16   ILE A CA   1 ? 
ATOM   225  C C    . ILE A 1 21  ? 24.663  -1.061  3.730   1.000 20.532 0 16   ILE A C    1 ? 
ATOM   226  O O    . ILE A 1 21  ? 24.033  -1.562  2.811   1.000 18.952 0 16   ILE A O    1 ? 
ATOM   227  C CB   . ILE A 1 21  ? 24.673  1.410   4.297   1.000 20.953 0 16   ILE A CB   1 ? 
ATOM   228  C CG1  . ILE A 1 21  ? 23.837  2.520   4.933   1.000 22.630 0 16   ILE A CG1  1 ? 
ATOM   229  C CG2  . ILE A 1 21  ? 24.820  1.642   2.810   1.000 23.430 0 16   ILE A CG2  1 ? 
ATOM   230  C CD1  . ILE A 1 21  ? 24.594  3.821   4.979   1.000 25.523 0 16   ILE A CD1  1 ? 
ATOM   231  H H    . ILE A 1 21  ? 24.664  0.324   6.528   1.000 21.038 0 16   ILE A H    1 c 
ATOM   232  H HA   . ILE A 1 21  ? 23.106  0.072   4.419   1.000 20.370 0 16   ILE A HA   1 c 
ATOM   233  H HB   . ILE A 1 21  ? 25.565  1.438   4.697   1.000 21.450 0 16   ILE A HB   1 c 
ATOM   234  H HG12 . ILE A 1 21  ? 23.016  2.643   4.414   1.000 22.863 0 16   ILE A HG12 1 c 
ATOM   235  H HG13 . ILE A 1 21  ? 23.589  2.259   5.843   1.000 22.856 0 16   ILE A HG13 1 c 
ATOM   236  H HG21 . ILE A 1 21  ? 25.095  2.558   2.646   1.000 22.688 0 16   ILE A HG21 1 c 
ATOM   237  H HG22 . ILE A 1 21  ? 23.969  1.477   2.369   1.000 22.652 0 16   ILE A HG22 1 c 
ATOM   238  H HG23 . ILE A 1 21  ? 25.491  1.038   2.449   1.000 22.656 0 16   ILE A HG23 1 c 
ATOM   239  H HD11 . ILE A 1 21  ? 25.474  3.674   5.377   1.000 24.597 0 16   ILE A HD11 1 c 
ATOM   240  H HD12 . ILE A 1 21  ? 24.098  4.463   5.522   1.000 24.614 0 16   ILE A HD12 1 c 
ATOM   241  H HD13 . ILE A 1 21  ? 24.703  4.177   4.078   1.000 24.601 0 16   ILE A HD13 1 c 
ATOM   242  N N    . ASP A 1 22  ? 25.890  -1.479  4.050   1.000 21.233 0 17   ASP A N    1 ? 
ATOM   243  C CA   . ASP A 1 22  ? 26.549  -2.440  3.211   1.000 22.789 0 17   ASP A CA   1 ? 
ATOM   244  C C    . ASP A 1 22  ? 25.808  -3.773  3.261   1.000 20.157 0 17   ASP A C    1 ? 
ATOM   245  O O    . ASP A 1 22  ? 25.860  -4.539  2.286   1.000 21.870 0 17   ASP A O    1 ? 
ATOM   246  C CB   . ASP A 1 22  ? 28.037  -2.547  3.563   1.000 23.391 0 17   ASP A CB   1 ? 
ATOM   247  C CG   . ASP A 1 22  ? 28.910  -1.378  3.116   1.000 30.332 0 17   ASP A CG   1 ? 
ATOM   248  O OD1  . ASP A 1 22  ? 28.453  -0.522  2.305   1.000 27.103 0 17   ASP A OD1  1 ? 
ATOM   249  O OD2  . ASP A 1 22  ? 30.054  -1.303  3.619   1.000 28.636 0 17   ASP A OD2  1 ? 
ATOM   250  H H    . ASP A 1 22  ? 26.316  -1.158  4.792   1.000 21.430 0 17   ASP A H    1 c 
ATOM   251  H HA   . ASP A 1 22  ? 26.507  -2.110  2.285   1.000 22.117 0 17   ASP A HA   1 c 
ATOM   252  H HB2  . ASP A 1 22  ? 28.124  -2.637  4.535   1.000 24.662 0 17   ASP A HB2  1 c 
ATOM   253  H HB3  . ASP A 1 22  ? 28.396  -3.363  3.156   1.000 24.660 0 17   ASP A HB3  1 c 
ATOM   254  N N    . ASP A 1 23  ? 25.248  -4.157  4.421   1.000 20.413 0 18   ASP A N    1 ? 
ATOM   255  C CA   . ASP A 1 23  ? 24.466  -5.383  4.495   1.000 21.307 0 18   ASP A CA   1 ? 
ATOM   256  C C    . ASP A 1 23  ? 23.231  -5.320  3.569   1.000 20.529 0 18   ASP A C    1 ? 
ATOM   257  O O    . ASP A 1 23  ? 22.887  -6.335  2.953   1.000 20.109 0 18   ASP A O    1 ? 
ATOM   258  C CB   . ASP A 1 23  ? 24.003  -5.731  5.899   1.000 20.587 0 18   ASP A CB   1 ? 
ATOM   259  C CG   . ASP A 1 23  ? 25.091  -6.231  6.851   1.000 24.966 0 18   ASP A CG   1 ? 
ATOM   260  O OD1  . ASP A 1 23  ? 26.181  -6.596  6.336   1.000 27.614 0 18   ASP A OD1  1 ? 
ATOM   261  O OD2  . ASP A 1 23  ? 24.781  -6.287  8.081   1.000 26.449 0 18   ASP A OD2  1 ? 
ATOM   262  H H    . ASP A 1 23  ? 25.360  -3.654  5.175   1.000 20.567 0 18   ASP A H    1 c 
ATOM   263  H HA   . ASP A 1 23  ? 25.036  -6.124  4.188   1.000 20.889 0 18   ASP A HA   1 c 
ATOM   264  H HB2  . ASP A 1 23  ? 23.591  -4.938  6.298   1.000 21.673 0 18   ASP A HB2  1 c 
ATOM   265  H HB3  . ASP A 1 23  ? 23.316  -6.426  5.840   1.000 21.679 0 18   ASP A HB3  1 c 
ATOM   266  N N    . VAL A 1 24  ? 22.592  -4.137  3.461   1.000 21.589 0 19   VAL A N    1 ? 
ATOM   267  C CA   . VAL A 1 24  ? 21.479  -3.977  2.521   1.000 19.404 0 19   VAL A CA   1 ? 
ATOM   268  C C    . VAL A 1 24  ? 21.974  -4.145  1.078   1.000 17.198 0 19   VAL A C    1 ? 
ATOM   269  O O    . VAL A 1 24  ? 21.343  -4.873  0.296   1.000 19.065 0 19   VAL A O    1 ? 
ATOM   270  C CB   . VAL A 1 24  ? 20.714  -2.657  2.706   1.000 19.380 0 19   VAL A CB   1 ? 
ATOM   271  C CG1  . VAL A 1 24  ? 19.651  -2.436  1.644   1.000 20.719 0 19   VAL A CG1  1 ? 
ATOM   272  C CG2  . VAL A 1 24  ? 20.135  -2.508  4.097   1.000 22.211 0 19   VAL A CG2  1 ? 
ATOM   273  H H    . VAL A 1 24  ? 22.849  -3.427  3.975   1.000 20.840 0 19   VAL A H    1 c 
ATOM   274  H HA   . VAL A 1 24  ? 20.848  -4.702  2.698   1.000 19.376 0 19   VAL A HA   1 c 
ATOM   275  H HB   . VAL A 1 24  ? 21.375  -1.934  2.597   1.000 20.136 0 19   VAL A HB   1 c 
ATOM   276  H HG11 . VAL A 1 24  ? 19.102  -3.235  1.563   1.000 20.314 0 19   VAL A HG11 1 c 
ATOM   277  H HG12 . VAL A 1 24  ? 20.075  -2.247  0.790   1.000 20.300 0 19   VAL A HG12 1 c 
ATOM   278  H HG13 . VAL A 1 24  ? 19.090  -1.684  1.897   1.000 20.328 0 19   VAL A HG13 1 c 
ATOM   279  H HG21 . VAL A 1 24  ? 19.625  -1.682  4.150   1.000 21.353 0 19   VAL A HG21 1 c 
ATOM   280  H HG22 . VAL A 1 24  ? 20.855  -2.483  4.749   1.000 21.323 0 19   VAL A HG22 1 c 
ATOM   281  H HG23 . VAL A 1 24  ? 19.552  -3.261  4.289   1.000 21.334 0 19   VAL A HG23 1 c 
ATOM   282  N N    . VAL A 1 25  ? 23.140  -3.550  0.755   1.000 18.657 0 20   VAL A N    1 ? 
ATOM   283  C CA   . VAL A 1 25  ? 23.745  -3.703  -0.544  1.000 19.169 0 20   VAL A CA   1 ? 
ATOM   284  C C    . VAL A 1 25  ? 24.014  -5.179  -0.847  1.000 19.076 0 20   VAL A C    1 ? 
ATOM   285  O O    . VAL A 1 25  ? 23.732  -5.644  -1.945  1.000 19.282 0 20   VAL A O    1 ? 
ATOM   286  C CB   . VAL A 1 25  ? 24.979  -2.798  -0.716  1.000 18.048 0 20   VAL A CB   1 ? 
ATOM   287  C CG1  . VAL A 1 25  ? 25.630  -3.014  -2.066  1.000 20.793 0 20   VAL A CG1  1 ? 
ATOM   288  C CG2  . VAL A 1 25  ? 24.624  -1.331  -0.465  1.000 20.018 0 20   VAL A CG2  1 ? 
ATOM   289  H H    . VAL A 1 25  ? 23.567  -3.040  1.382   1.000 18.452 0 20   VAL A H    1 c 
ATOM   290  H HA   . VAL A 1 25  ? 23.083  -3.399  -1.196  1.000 18.835 0 20   VAL A HA   1 c 
ATOM   291  H HB   . VAL A 1 25  ? 25.631  -3.067  -0.027  1.000 19.108 0 20   VAL A HB   1 c 
ATOM   292  H HG11 . VAL A 1 25  ? 24.952  -2.982  -2.762  1.000 19.936 0 20   VAL A HG11 1 c 
ATOM   293  H HG12 . VAL A 1 25  ? 26.069  -3.881  -2.082  1.000 19.933 0 20   VAL A HG12 1 c 
ATOM   294  H HG13 . VAL A 1 25  ? 26.288  -2.317  -2.224  1.000 19.933 0 20   VAL A HG13 1 c 
ATOM   295  H HG21 . VAL A 1 25  ? 25.391  -0.772  -0.674  1.000 19.418 0 20   VAL A HG21 1 c 
ATOM   296  H HG22 . VAL A 1 25  ? 24.381  -1.207  0.465   1.000 19.404 0 20   VAL A HG22 1 c 
ATOM   297  H HG23 . VAL A 1 25  ? 23.876  -1.077  -1.031  1.000 19.415 0 20   VAL A HG23 1 c 
ATOM   298  N N    . ARG A 1 26  ? 24.529  -5.952  0.127   1.000 20.229 0 21   ARG A N    1 ? 
ATOM   299  C CA   . ARG A 1 26  ? 24.748  -7.370  -0.097  1.000 22.215 0 21   ARG A CA   1 ? 
ATOM   300  C C    . ARG A 1 26  ? 23.462  -8.127  -0.422  1.000 18.858 0 21   ARG A C    1 ? 
ATOM   301  O O    . ARG A 1 26  ? 23.456  -9.040  -1.266  1.000 20.559 0 21   ARG A O    1 ? 
ATOM   302  C CB   . ARG A 1 26  ? 25.436  -8.013  1.123   1.000 25.551 0 21   ARG A CB   1 ? 
ATOM   303  C CG   . ARG A 1 26  ? 26.912  -7.717  1.267   1.000 30.006 0 21   ARG A CG   1 ? 
ATOM   304  C CD   . ARG A 1 26  ? 27.337  -8.336  2.626   1.000 37.048 0 21   ARG A CD   1 ? 
ATOM   305  N NE   . ARG A 1 26  ? 28.598  -7.703  2.987   1.000 39.679 0 21   ARG A NE   1 ? 
ATOM   306  C CZ   . ARG A 1 26  ? 28.894  -6.590  3.640   1.000 41.037 0 21   ARG A CZ   1 ? 
ATOM   307  N NH1  . ARG A 1 26  ? 28.220  -6.137  4.678   1.000 38.247 0 21   ARG A NH1  1 ? 
ATOM   308  N NH2  . ARG A 1 26  ? 30.027  -6.004  3.321   1.000 49.703 0 21   ARG A NH2  1 ? 
ATOM   309  H H    . ARG A 1 26  ? 24.750  -5.587  0.935   1.000 20.421 0 21   ARG A H    1 c 
ATOM   310  H HA   . ARG A 1 26  ? 25.361  -7.463  -0.871  1.000 21.701 0 21   ARG A HA   1 c 
ATOM   311  H HB2  . ARG A 1 26  ? 24.975  -7.706  1.933   1.000 25.729 0 21   ARG A HB2  1 c 
ATOM   312  H HB3  . ARG A 1 26  ? 25.318  -8.986  1.069   1.000 25.657 0 21   ARG A HB3  1 c 
ATOM   313  H HG2  . ARG A 1 26  ? 27.418  -8.135  0.536   1.000 30.313 0 21   ARG A HG2  1 c 
ATOM   314  H HG3  . ARG A 1 26  ? 27.068  -6.748  1.277   1.000 30.312 0 21   ARG A HG3  1 c 
ATOM   315  H HD2  . ARG A 1 26  ? 26.668  -8.160  3.319   1.000 35.811 0 21   ARG A HD2  1 c 
ATOM   316  H HD3  . ARG A 1 26  ? 27.463  -9.303  2.542   1.000 35.936 0 21   ARG A HD3  1 c 
ATOM   317  H HE   . ARG A 1 26  ? 29.304  -8.145  2.729   1.000 39.485 0 21   ARG A HE   1 c 
ATOM   318  H HH11 . ARG A 1 26  ? 28.397  -5.335  5.008   1.000 39.218 0 21   ARG A HH11 1 c 
ATOM   319  H HH12 . ARG A 1 26  ? 27.589  -6.638  5.042   1.000 39.116 0 21   ARG A HH12 1 c 
ATOM   320  H HH21 . ARG A 1 26  ? 30.359  -5.371  3.844   1.000 46.677 0 21   ARG A HH21 1 c 
ATOM   321  H HH22 . ARG A 1 26  ? 30.457  -6.240  2.584   1.000 46.686 0 21   ARG A HH22 1 c 
ATOM   322  N N    . LEU A 1 27  ? 22.357  -7.759  0.237   1.000 19.356 0 22   LEU A N    1 ? 
ATOM   323  C CA   . LEU A 1 27  ? 21.072  -8.371  -0.011  1.000 20.161 0 22   LEU A CA   1 ? 
ATOM   324  C C    . LEU A 1 27  ? 20.634  -8.095  -1.454  1.000 19.028 0 22   LEU A C    1 ? 
ATOM   325  O O    . LEU A 1 27  ? 20.158  -8.997  -2.162  1.000 19.016 0 22   LEU A O    1 ? 
ATOM   326  C CB   . LEU A 1 27  ? 20.018  -7.892  0.986   1.000 20.301 0 22   LEU A CB   1 ? 
ATOM   327  C CG   . LEU A 1 27  ? 18.633  -8.497  0.721   1.000 21.680 0 22   LEU A CG   1 ? 
ATOM   328  C CD1  . LEU A 1 27  ? 18.614  -10.016 0.854   1.000 24.308 0 22   LEU A CD1  1 ? 
ATOM   329  C CD2  . LEU A 1 27  ? 17.539  -7.822  1.564   1.000 22.932 0 22   LEU A CD2  1 ? 
ATOM   330  H H    . LEU A 1 27  ? 22.414  -7.103  0.871   1.000 19.444 0 22   LEU A H    1 c 
ATOM   331  H HA   . LEU A 1 27  ? 21.183  -9.350  0.091   1.000 19.855 0 22   LEU A HA   1 c 
ATOM   332  H HB2  . LEU A 1 27  ? 20.306  -8.144  1.893   1.000 20.571 0 22   LEU A HB2  1 c 
ATOM   333  H HB3  . LEU A 1 27  ? 19.951  -6.912  0.927   1.000 20.564 0 22   LEU A HB3  1 c 
ATOM   334  H HG   . LEU A 1 27  ? 18.406  -8.300  -0.224  1.000 22.082 0 22   LEU A HG   1 c 
ATOM   335  H HD11 . LEU A 1 27  ? 19.121  -10.413 0.126   1.000 23.457 0 22   LEU A HD11 1 c 
ATOM   336  H HD12 . LEU A 1 27  ? 17.696  -10.333 0.818   1.000 23.492 0 22   LEU A HD12 1 c 
ATOM   337  H HD13 . LEU A 1 27  ? 19.011  -10.273 1.703   1.000 23.492 0 22   LEU A HD13 1 c 
ATOM   338  H HD21 . LEU A 1 27  ? 17.572  -6.860  1.430   1.000 22.557 0 22   LEU A HD21 1 c 
ATOM   339  H HD22 . LEU A 1 27  ? 17.683  -8.024  2.503   1.000 22.551 0 22   LEU A HD22 1 c 
ATOM   340  H HD23 . LEU A 1 27  ? 16.667  -8.157  1.293   1.000 22.557 0 22   LEU A HD23 1 c 
ATOM   341  N N    . PHE A 1 28  ? 20.779  -6.842  -1.894  1.000 17.868 0 23   PHE A N    1 ? 
ATOM   342  C CA   . PHE A 1 28  ? 20.415  -6.497  -3.257  1.000 17.372 0 23   PHE A CA   1 ? 
ATOM   343  C C    . PHE A 1 28  ? 21.304  -7.220  -4.269  1.000 16.764 0 23   PHE A C    1 ? 
ATOM   344  O O    . PHE A 1 28  ? 20.822  -7.738  -5.272  1.000 19.053 0 23   PHE A O    1 ? 
ATOM   345  C CB   . PHE A 1 28  ? 20.466  -4.969  -3.449  1.000 17.404 0 23   PHE A CB   1 ? 
ATOM   346  C CG   . PHE A 1 28  ? 19.171  -4.275  -3.062  1.000 17.598 0 23   PHE A CG   1 ? 
ATOM   347  C CD1  . PHE A 1 28  ? 18.822  -4.095  -1.738  1.000 17.539 0 23   PHE A CD1  1 ? 
ATOM   348  C CD2  . PHE A 1 28  ? 18.296  -3.822  -4.043  1.000 18.496 0 23   PHE A CD2  1 ? 
ATOM   349  C CE1  . PHE A 1 28  ? 17.633  -3.480  -1.367  1.000 16.635 0 23   PHE A CE1  1 ? 
ATOM   350  C CE2  . PHE A 1 28  ? 17.119  -3.155  -3.685  1.000 17.988 0 23   PHE A CE2  1 ? 
ATOM   351  C CZ   . PHE A 1 28  ? 16.743  -3.046  -2.371  1.000 17.450 0 23   PHE A CZ   1 ? 
ATOM   352  H H    . PHE A 1 28  ? 21.101  -6.193  -1.337  1.000 18.037 0 23   PHE A H    1 c 
ATOM   353  H HA   . PHE A 1 28  ? 19.477  -6.793  -3.407  1.000 17.377 0 23   PHE A HA   1 c 
ATOM   354  H HB2  . PHE A 1 28  ? 21.200  -4.606  -2.905  1.000 17.449 0 23   PHE A HB2  1 c 
ATOM   355  H HB3  . PHE A 1 28  ? 20.662  -4.776  -4.393  1.000 17.449 0 23   PHE A HB3  1 c 
ATOM   356  H HD1  . PHE A 1 28  ? 19.397  -4.422  -1.067  1.000 17.358 0 23   PHE A HD1  1 c 
ATOM   357  H HD2  . PHE A 1 28  ? 18.524  -3.917  -4.954  1.000 18.138 0 23   PHE A HD2  1 c 
ATOM   358  H HE1  . PHE A 1 28  ? 17.411  -3.382  -0.454  1.000 17.045 0 23   PHE A HE1  1 c 
ATOM   359  H HE2  . PHE A 1 28  ? 16.526  -2.870  -4.361  1.000 17.955 0 23   PHE A HE2  1 c 
ATOM   360  H HZ   . PHE A 1 28  ? 15.951  -2.593  -2.142  1.000 17.407 0 23   PHE A HZ   1 c 
ATOM   361  N N    . ALA A 1 29  ? 22.582  -7.349  -3.976  1.000 18.294 0 24   ALA A N    1 ? 
ATOM   362  C CA   . ALA A 1 29  ? 23.486  -8.078  -4.859  1.000 19.535 0 24   ALA A CA   1 ? 
ATOM   363  C C    . ALA A 1 29  ? 23.062  -9.538  -4.969  1.000 18.755 0 24   ALA A C    1 ? 
ATOM   364  O O    . ALA A 1 29  ? 23.055  -10.128 -6.061  1.000 21.048 0 24   ALA A O    1 ? 
ATOM   365  C CB   . ALA A 1 29  ? 24.883  -7.935  -4.377  1.000 20.634 0 24   ALA A CB   1 ? 
ATOM   366  H H    . ALA A 1 29  ? 22.915  -6.971  -3.213  1.000 18.191 0 24   ALA A H    1 c 
ATOM   367  H HA   . ALA A 1 29  ? 23.420  -7.672  -5.768  1.000 19.328 0 24   ALA A HA   1 c 
ATOM   368  H HB1  . ALA A 1 29  ? 25.131  -6.996  -4.369  1.000 20.297 0 24   ALA A HB1  1 c 
ATOM   369  H HB2  . ALA A 1 29  ? 24.956  -8.294  -3.476  1.000 20.297 0 24   ALA A HB2  1 c 
ATOM   370  H HB3  . ALA A 1 29  ? 25.484  -8.421  -4.966  1.000 20.297 0 24   ALA A HB3  1 c 
ATOM   371  N N    . ALA A 1 30  ? 22.698  -10.152 -3.841  1.000 19.939 0 25   ALA A N    1 ? 
ATOM   372  C CA   . ALA A 1 30  ? 22.278  -11.539 -3.849  1.000 20.773 0 25   ALA A CA   1 ? 
ATOM   373  C C    . ALA A 1 30  ? 20.996  -11.732 -4.664  1.000 21.331 0 25   ALA A C    1 ? 
ATOM   374  O O    . ALA A 1 30  ? 20.883  -12.639 -5.513  1.000 23.080 0 25   ALA A O    1 ? 
ATOM   375  C CB   . ALA A 1 30  ? 22.135  -12.042 -2.433  1.000 21.240 0 25   ALA A CB   1 ? 
ATOM   376  H H    . ALA A 1 30  ? 22.716  -9.698  -3.048  1.000 19.830 0 25   ALA A H    1 c 
ATOM   377  H HA   . ALA A 1 30  ? 22.998  -12.067 -4.295  1.000 20.784 0 25   ALA A HA   1 c 
ATOM   378  H HB1  . ALA A 1 30  ? 22.987  -11.970 -1.972  1.000 21.100 0 25   ALA A HB1  1 c 
ATOM   379  H HB2  . ALA A 1 30  ? 21.470  -11.512 -1.963  1.000 21.100 0 25   ALA A HB2  1 c 
ATOM   380  H HB3  . ALA A 1 30  ? 21.854  -12.973 -2.443  1.000 21.100 0 25   ALA A HB3  1 c 
ATOM   381  N N    . GLU A 1 31  ? 20.004  -10.871 -4.411  1.000 21.836 0 26   GLU A N    1 ? 
ATOM   382  C CA   . GLU A 1 31  ? 18.766  -10.949 -5.164  1.000 20.647 0 26   GLU A CA   1 ? 
ATOM   383  C C    . GLU A 1 31  ? 18.984  -10.741 -6.656  1.000 20.892 0 26   GLU A C    1 ? 
ATOM   384  O O    . GLU A 1 31  ? 18.297  -11.368 -7.475  1.000 22.212 0 26   GLU A O    1 ? 
ATOM   385  C CB   . GLU A 1 31  ? 17.713  -9.992  -4.608  1.000 20.527 0 26   GLU A CB   1 ? 
ATOM   386  C CG   . GLU A 1 31  ? 17.150  -10.491 -3.284  1.000 21.493 0 26   GLU A CG   1 ? 
ATOM   387  C CD   . GLU A 1 31  ? 16.346  -11.763 -3.417  1.000 23.940 0 26   GLU A CD   1 ? 
ATOM   388  O OE1  . GLU A 1 31  ? 15.569  -11.955 -4.367  1.000 22.936 0 26   GLU A OE1  1 ? 
ATOM   389  O OE2  . GLU A 1 31  ? 16.448  -12.613 -2.497  1.000 26.917 0 26   GLU A OE2  1 ? 
ATOM   390  H H    . GLU A 1 31  ? 20.096  -10.233 -3.762  1.000 21.417 0 26   GLU A H    1 c 
ATOM   391  H HA   . GLU A 1 31  ? 18.410  -11.866 -5.048  1.000 20.925 0 26   GLU A HA   1 c 
ATOM   392  H HB2  . GLU A 1 31  ? 18.118  -9.109  -4.481  1.000 20.776 0 26   GLU A HB2  1 c 
ATOM   393  H HB3  . GLU A 1 31  ? 16.987  -9.899  -5.261  1.000 20.782 0 26   GLU A HB3  1 c 
ATOM   394  H HG2  . GLU A 1 31  ? 17.890  -10.651 -2.660  1.000 21.827 0 26   GLU A HG2  1 c 
ATOM   395  H HG3  . GLU A 1 31  ? 16.576  -9.796  -2.896  1.000 21.778 0 26   GLU A HG3  1 c 
ATOM   396  N N    . LEU A 1 32  ? 19.887  -9.814  -7.027  1.000 20.955 0 27   LEU A N    1 ? 
ATOM   397  C CA   . LEU A 1 32  ? 20.060  -9.467  -8.427  1.000 24.742 0 27   LEU A CA   1 ? 
ATOM   398  C C    . LEU A 1 32  ? 20.826  -10.578 -9.141  1.000 27.120 0 27   LEU A C    1 ? 
ATOM   399  O O    . LEU A 1 32  ? 20.849  -10.629 -10.366 1.000 29.826 0 27   LEU A O    1 ? 
ATOM   400  C CB   . LEU A 1 32  ? 20.773  -8.125  -8.556  1.000 22.560 0 27   LEU A CB   1 ? 
ATOM   401  C CG   . LEU A 1 32  ? 19.911  -6.885  -8.297  1.000 22.342 0 27   LEU A CG   1 ? 
ATOM   402  C CD1  . LEU A 1 32  ? 20.777  -5.681  -8.028  1.000 20.190 0 27   LEU A CD1  1 ? 
ATOM   403  C CD2  . LEU A 1 32  ? 18.982  -6.663  -9.483  1.000 22.003 0 27   LEU A CD2  1 ? 
ATOM   404  H H    . LEU A 1 32  ? 20.397  -9.394  -6.396  1.000 21.747 0 27   LEU A H    1 c 
ATOM   405  H HA   . LEU A 1 32  ? 19.163  -9.395  -8.839  1.000 23.903 0 27   LEU A HA   1 c 
ATOM   406  H HB2  . LEU A 1 32  ? 21.529  -8.116  -7.925  1.000 22.953 0 27   LEU A HB2  1 c 
ATOM   407  H HB3  . LEU A 1 32  ? 21.144  -8.060  -9.466  1.000 22.994 0 27   LEU A HB3  1 c 
ATOM   408  H HG   . LEU A 1 32  ? 19.354  -7.055  -7.493  1.000 21.898 0 27   LEU A HG   1 c 
ATOM   409  H HD11 . LEU A 1 32  ? 21.323  -5.842  -7.240  1.000 20.822 0 27   LEU A HD11 1 c 
ATOM   410  H HD12 . LEU A 1 32  ? 20.214  -4.903  -7.876  1.000 20.811 0 27   LEU A HD12 1 c 
ATOM   411  H HD13 . LEU A 1 32  ? 21.353  -5.518  -8.793  1.000 20.811 0 27   LEU A HD13 1 c 
ATOM   412  H HD21 . LEU A 1 32  ? 18.384  -7.423  -9.578  1.000 22.149 0 27   LEU A HD21 1 c 
ATOM   413  H HD22 . LEU A 1 32  ? 19.509  -6.563  -10.294 1.000 22.202 0 27   LEU A HD22 1 c 
ATOM   414  H HD23 . LEU A 1 32  ? 18.458  -5.857  -9.339  1.000 22.131 0 27   LEU A HD23 1 c 
ATOM   415  N N    . GLY A 1 33  ? 21.426  -11.463 -8.364  1.000 25.824 0 28   GLY A N    1 ? 
ATOM   416  C CA   . GLY A 1 33  ? 22.126  -12.621 -8.910  1.000 30.147 0 28   GLY A CA   1 ? 
ATOM   417  C C    . GLY A 1 33  ? 21.200  -13.820 -9.069  1.000 35.778 0 28   GLY A C    1 ? 
ATOM   418  O O    . GLY A 1 33  ? 21.603  -14.842 -9.649  1.000 37.272 0 28   GLY A O    1 ? 
ATOM   419  H H    . GLY A 1 33  ? 21.430  -11.341 -7.459  1.000 26.902 0 28   GLY A H    1 c 
ATOM   420  H HA2  . GLY A 1 33  ? 22.513  -12.385 -9.786  1.000 30.176 0 28   GLY A HA2  1 c 
ATOM   421  H HA3  . GLY A 1 33  ? 22.869  -12.860 -8.306  1.000 30.190 0 28   GLY A HA3  1 c 
ATOM   422  N N    . ARG A 1 34  ? 19.979  -13.704 -8.535  1.000 31.763 0 29   ARG A N    1 ? 
ATOM   423  C CA   . ARG A 1 34  ? 19.024  -14.797 -8.600  1.000 35.976 0 29   ARG A CA   1 ? 
ATOM   424  C C    . ARG A 1 34  ? 18.327  -14.725 -9.948  1.000 36.232 0 29   ARG A C    1 ? 
ATOM   425  O O    . ARG A 1 34  ? 18.384  -13.734 -10.665 1.000 36.711 0 29   ARG A O    1 ? 
ATOM   426  C CB   . ARG A 1 34  ? 18.039  -14.824 -7.424  1.000 34.627 0 29   ARG A CB   1 ? 
ATOM   427  C CG   . ARG A 1 34  ? 18.733  -15.115 -6.104  1.000 39.207 0 29   ARG A CG   1 ? 
ATOM   428  C CD   . ARG A 1 34  ? 17.825  -14.948 -4.881  1.000 45.219 0 29   ARG A CD   1 ? 
ATOM   429  N NE   . ARG A 1 34  ? 16.796  -15.990 -4.839  1.000 51.672 0 29   ARG A NE   1 ? 
ATOM   430  C CZ   . ARG A 1 34  ? 17.030  -17.265 -4.502  1.000 57.529 0 29   ARG A CZ   1 ? 
ATOM   431  N NH1  . ARG A 1 34  ? 16.038  -18.143 -4.484  1.000 64.520 0 29   ARG A NH1  1 ? 
ATOM   432  N NH2  . ARG A 1 34  ? 18.249  -17.654 -4.164  1.000 54.289 0 29   ARG A NH2  1 ? 
ATOM   433  H H    . ARG A 1 34  ? 19.735  -12.932 -8.113  1.000 33.377 0 29   ARG A H    1 c 
ATOM   434  H HA   . ARG A 1 34  ? 19.534  -15.646 -8.567  1.000 34.981 0 29   ARG A HA   1 c 
ATOM   435  H HB2  . ARG A 1 34  ? 17.585  -13.957 -7.364  1.000 35.849 0 29   ARG A HB2  1 c 
ATOM   436  H HB3  . ARG A 1 34  ? 17.360  -15.512 -7.588  1.000 35.952 0 29   ARG A HB3  1 c 
ATOM   437  H HG2  . ARG A 1 34  ? 19.077  -16.034 -6.121  1.000 39.459 0 29   ARG A HG2  1 c 
ATOM   438  H HG3  . ARG A 1 34  ? 19.503  -14.516 -6.010  1.000 39.203 0 29   ARG A HG3  1 c 
ATOM   439  H HD2  . ARG A 1 34  ? 18.364  -14.992 -4.067  1.000 45.252 0 29   ARG A HD2  1 c 
ATOM   440  H HD3  . ARG A 1 34  ? 17.394  -14.070 -4.913  1.000 45.091 0 29   ARG A HD3  1 c 
ATOM   441  H HE   . ARG A 1 34  ? 15.980  -15.766 -5.046  1.000 51.557 0 29   ARG A HE   1 c 
ATOM   442  H HH11 . ARG A 1 34  ? 16.199  -18.982 -4.257  1.000 62.172 0 29   ARG A HH11 1 c 
ATOM   443  H HH12 . ARG A 1 34  ? 15.219  -17.889 -4.699  1.000 62.078 0 29   ARG A HH12 1 c 
ATOM   444  H HH21 . ARG A 1 34  ? 18.615  -18.348 -4.577  1.000 55.228 0 29   ARG A HH21 1 c 
ATOM   445  H HH22 . ARG A 1 34  ? 18.691  -17.226 -3.527  1.000 55.104 0 29   ARG A HH22 1 c 
ATOM   446  N N    . GLU A 1 35  ? 17.705  -15.845 -10.288 1.000 43.831 0 30   GLU A N    1 ? 
ATOM   447  C CA   . GLU A 1 35  ? 16.819  -15.959 -11.437 1.000 48.163 0 30   GLU A CA   1 ? 
ATOM   448  C C    . GLU A 1 35  ? 15.956  -14.698 -11.586 1.000 43.551 0 30   GLU A C    1 ? 
ATOM   449  O O    . GLU A 1 35  ? 15.967  -14.054 -12.625 1.000 39.379 0 30   GLU A O    1 ? 
ATOM   450  C CB   . GLU A 1 35  ? 16.077  -17.291 -11.247 1.000 49.809 0 30   GLU A CB   1 ? 
ATOM   451  C CG   . GLU A 1 35  ? 15.602  -17.602 -9.820  1.000 49.712 0 30   GLU A CG   1 ? 
ATOM   452  C CD   . GLU A 1 35  ? 16.494  -18.203 -8.719  1.000 53.787 0 30   GLU A CD   1 ? 
ATOM   453  O OE1  . GLU A 1 35  ? 15.835  -18.530 -7.712  1.000 56.606 0 30   GLU A OE1  1 ? 
ATOM   454  O OE2  . GLU A 1 35  ? 17.751  -18.351 -8.751  1.000 47.702 0 30   GLU A OE2  1 ? 
ATOM   455  H H    . GLU A 1 35  ? 17.875  -16.595 -9.797  1.000 42.828 0 30   GLU A H    1 c 
ATOM   456  H HA   . GLU A 1 35  ? 17.383  -16.040 -12.248 1.000 46.663 0 30   GLU A HA   1 c 
ATOM   457  H HB2  . GLU A 1 35  ? 15.294  -17.297 -11.836 1.000 49.409 0 30   GLU A HB2  1 c 
ATOM   458  H HB3  . GLU A 1 35  ? 16.668  -18.018 -11.535 1.000 49.409 0 30   GLU A HB3  1 c 
ATOM   459  H HG2  . GLU A 1 35  ? 15.233  -16.775 -9.453  1.000 50.437 0 30   GLU A HG2  1 c 
ATOM   460  H HG3  . GLU A 1 35  ? 14.830  -18.202 -9.905  1.000 50.638 0 30   GLU A HG3  1 c 
ATOM   461  N N    . GLU A 1 36  ? 15.158  -14.384 -10.560 1.000 36.336 0 31   GLU A N    1 ? 
ATOM   462  C CA   . GLU A 1 36  ? 14.287  -13.223 -10.520 1.000 38.536 0 31   GLU A CA   1 ? 
ATOM   463  C C    . GLU A 1 36  ? 14.445  -12.573 -9.145  1.000 31.694 0 31   GLU A C    1 ? 
ATOM   464  O O    . GLU A 1 36  ? 14.073  -13.188 -8.145  1.000 33.227 0 31   GLU A O    1 ? 
ATOM   465  C CB   . GLU A 1 36  ? 12.794  -13.537 -10.541 1.000 41.460 0 31   GLU A CB   1 ? 
ATOM   466  C CG   . GLU A 1 36  ? 12.253  -13.985 -11.899 1.000 45.752 0 31   GLU A CG   1 ? 
ATOM   467  C CD   . GLU A 1 36  ? 10.844  -13.485 -12.226 1.000 44.038 0 31   GLU A CD   1 ? 
ATOM   468  O OE1  . GLU A 1 36  ? 10.160  -12.936 -11.356 1.000 33.537 0 31   GLU A OE1  1 ? 
ATOM   469  O OE2  . GLU A 1 36  ? 10.446  -13.611 -13.394 1.000 39.552 0 31   GLU A OE2  1 ? 
ATOM   470  H H    . GLU A 1 36  ? 15.173  -14.926 -9.825  1.000 38.654 0 31   GLU A H    1 c 
ATOM   471  H HA   . GLU A 1 36  ? 14.537  -12.589 -11.236 1.000 37.093 0 31   GLU A HA   1 c 
ATOM   472  H HB2  . GLU A 1 36  ? 12.613  -14.251 -9.894  1.000 41.525 0 31   GLU A HB2  1 c 
ATOM   473  H HB3  . GLU A 1 36  ? 12.303  -12.741 -10.250 1.000 41.350 0 31   GLU A HB3  1 c 
ATOM   474  H HG2  . GLU A 1 36  ? 12.862  -13.673 -12.601 1.000 44.317 0 31   GLU A HG2  1 c 
ATOM   475  H HG3  . GLU A 1 36  ? 12.248  -14.966 -11.930 1.000 44.345 0 31   GLU A HG3  1 c 
ATOM   476  N N    . PRO A 1 37  ? 14.940  -11.324 -9.039  1.000 25.599 0 32   PRO A N    1 ? 
ATOM   477  C CA   . PRO A 1 37  ? 14.980  -10.659 -7.739  1.000 20.762 0 32   PRO A CA   1 ? 
ATOM   478  C C    . PRO A 1 37  ? 13.583  -10.525 -7.156  1.000 20.612 0 32   PRO A C    1 ? 
ATOM   479  O O    . PRO A 1 37  ? 12.604  -10.281 -7.864  1.000 20.082 0 32   PRO A O    1 ? 
ATOM   480  C CB   . PRO A 1 37  ? 15.634  -9.316  -8.032  1.000 22.407 0 32   PRO A CB   1 ? 
ATOM   481  C CG   . PRO A 1 37  ? 15.309  -9.076  -9.469  1.000 25.370 0 32   PRO A CG   1 ? 
ATOM   482  C CD   . PRO A 1 37  ? 15.388  -10.435 -10.127 1.000 24.164 0 32   PRO A CD   1 ? 
ATOM   483  H HA   . PRO A 1 37  ? 15.555  -11.181 -7.126  1.000 21.910 0 32   PRO A HA   1 c 
ATOM   484  H HB2  . PRO A 1 37  ? 15.257  -8.606  -7.461  1.000 22.652 0 32   PRO A HB2  1 c 
ATOM   485  H HB3  . PRO A 1 37  ? 16.608  -9.359  -7.893  1.000 22.660 0 32   PRO A HB3  1 c 
ATOM   486  H HG2  . PRO A 1 37  ? 14.410  -8.697  -9.564  1.000 24.388 0 32   PRO A HG2  1 c 
ATOM   487  H HG3  . PRO A 1 37  ? 15.954  -8.458  -9.873  1.000 24.388 0 32   PRO A HG3  1 c 
ATOM   488  H HD2  . PRO A 1 37  ? 14.789  -10.487 -10.904 1.000 24.892 0 32   PRO A HD2  1 c 
ATOM   489  H HD3  . PRO A 1 37  ? 16.307  -10.645 -10.406 1.000 24.783 0 32   PRO A HD3  1 c 
ATOM   490  N N    . ASP A 1 38  ? 13.510  -10.674 -5.824  1.000 19.299 0 33   ASP A N    1 ? 
ATOM   491  C CA   . ASP A 1 38  ? 12.235  -10.676 -5.137  1.000 18.917 0 33   ASP A CA   1 ? 
ATOM   492  C C    . ASP A 1 38  ? 11.834  -9.240  -4.819  1.000 19.465 0 33   ASP A C    1 ? 
ATOM   493  O O    . ASP A 1 38  ? 12.357  -8.650  -3.889  1.000 16.803 0 33   ASP A O    1 ? 
ATOM   494  C CB   . ASP A 1 38  ? 12.307  -11.595 -3.914  1.000 19.187 0 33   ASP A CB   1 ? 
ATOM   495  C CG   . ASP A 1 38  ? 11.009  -11.774 -3.161  1.000 21.756 0 33   ASP A CG   1 ? 
ATOM   496  O OD1  . ASP A 1 38  ? 10.170  -10.857 -3.200  1.000 19.968 0 33   ASP A OD1  1 ? 
ATOM   497  O OD2  . ASP A 1 38  ? 10.800  -12.886 -2.567  1.000 21.696 0 33   ASP A OD2  1 ? 
ATOM   498  H H    . ASP A 1 38  ? 14.276  -10.773 -5.335  1.000 19.541 0 33   ASP A H    1 c 
ATOM   499  H HA   . ASP A 1 38  ? 11.560  -11.061 -5.741  1.000 19.124 0 33   ASP A HA   1 c 
ATOM   500  H HB2  . ASP A 1 38  ? 12.612  -12.479 -4.208  1.000 19.733 0 33   ASP A HB2  1 c 
ATOM   501  H HB3  . ASP A 1 38  ? 12.974  -11.238 -3.292  1.000 19.699 0 33   ASP A HB3  1 c 
ATOM   502  N N    . LEU A 1 39  ? 10.884  -8.676  -5.590  1.000 16.724 0 34   LEU A N    1 ? 
ATOM   503  C CA   . LEU A 1 39  ? 10.520  -7.284  -5.464  1.000 16.019 0 34   LEU A CA   1 ? 
ATOM   504  C C    . LEU A 1 39  ? 9.909   -6.969  -4.102  1.000 15.614 0 34   LEU A C    1 ? 
ATOM   505  O O    . LEU A 1 39  ? 10.108  -5.878  -3.554  1.000 16.095 0 34   LEU A O    1 ? 
ATOM   506  C CB   . LEU A 1 39  ? 9.558   -6.870  -6.576  1.000 15.899 0 34   LEU A CB   1 ? 
ATOM   507  C CG   . LEU A 1 39  ? 10.116  -6.990  -8.008  1.000 17.025 0 34   LEU A CG   1 ? 
ATOM   508  C CD1  . LEU A 1 39  ? 9.047   -6.560  -8.981  1.000 18.764 0 34   LEU A CD1  1 ? 
ATOM   509  C CD2  . LEU A 1 39  ? 11.343  -6.176  -8.200  1.000 17.298 0 34   LEU A CD2  1 ? 
ATOM   510  H H    . LEU A 1 39  ? 10.450  -9.188  -6.210  1.000 17.188 0 34   LEU A H    1 c 
ATOM   511  H HA   . LEU A 1 39  ? 11.349  -6.750  -5.548  1.000 16.088 0 34   LEU A HA   1 c 
ATOM   512  H HB2  . LEU A 1 39  ? 8.749   -7.429  -6.508  1.000 16.173 0 34   LEU A HB2  1 c 
ATOM   513  H HB3  . LEU A 1 39  ? 9.293   -5.934  -6.422  1.000 16.171 0 34   LEU A HB3  1 c 
ATOM   514  H HG   . LEU A 1 39  ? 10.337  -7.941  -8.182  1.000 17.173 0 34   LEU A HG   1 c 
ATOM   515  H HD11 . LEU A 1 39  ? 8.249   -7.100  -8.847  1.000 18.225 0 34   LEU A HD11 1 c 
ATOM   516  H HD12 . LEU A 1 39  ? 9.368   -6.681  -9.889  1.000 18.211 0 34   LEU A HD12 1 c 
ATOM   517  H HD13 . LEU A 1 39  ? 8.832   -5.624  -8.835  1.000 18.225 0 34   LEU A HD13 1 c 
ATOM   518  H HD21 . LEU A 1 39  ? 12.082  -6.583  -7.718  1.000 17.204 0 34   LEU A HD21 1 c 
ATOM   519  H HD22 . LEU A 1 39  ? 11.192  -5.277  -7.864  1.000 17.215 0 34   LEU A HD22 1 c 
ATOM   520  H HD23 . LEU A 1 39  ? 11.560  -6.134  -9.147  1.000 17.227 0 34   LEU A HD23 1 c 
ATOM   521  N N    . VAL A 1 40  ? 9.124   -7.913  -3.588  1.000 16.239 0 35   VAL A N    1 ? 
ATOM   522  C CA   . VAL A 1 40  ? 8.407   -7.747  -2.321  1.000 17.186 0 35   VAL A CA   1 ? 
ATOM   523  C C    . VAL A 1 40  ? 9.408   -7.672  -1.163  1.000 17.346 0 35   VAL A C    1 ? 
ATOM   524  O O    . VAL A 1 40  ? 9.348   -6.728  -0.356  1.000 17.096 0 35   VAL A O    1 ? 
ATOM   525  C CB   . VAL A 1 40  ? 7.379   -8.857  -2.117  1.000 19.354 0 35   VAL A CB   1 ? 
ATOM   526  C CG1  . VAL A 1 40  ? 6.719   -8.765  -0.751  1.000 21.289 0 35   VAL A CG1  1 ? 
ATOM   527  C CG2  . VAL A 1 40  ? 6.317   -8.839  -3.221  1.000 20.044 0 35   VAL A CG2  1 ? 
ATOM   528  H H    . VAL A 1 40  ? 9.027   -8.701  -4.041  1.000 16.357 0 35   VAL A H    1 c 
ATOM   529  H HA   . VAL A 1 40  ? 7.929   -6.899  -2.361  1.000 17.413 0 35   VAL A HA   1 c 
ATOM   530  H HB   . VAL A 1 40  ? 7.860   -9.716  -2.169  1.000 19.392 0 35   VAL A HB   1 c 
ATOM   531  H HG11 . VAL A 1 40  ? 6.418   -7.853  -0.596  1.000 20.690 0 35   VAL A HG11 1 c 
ATOM   532  H HG12 . VAL A 1 40  ? 7.357   -9.016  -0.062  1.000 20.672 0 35   VAL A HG12 1 c 
ATOM   533  H HG13 . VAL A 1 40  ? 5.957   -9.367  -0.717  1.000 20.683 0 35   VAL A HG13 1 c 
ATOM   534  H HG21 . VAL A 1 40  ? 5.645   -9.517  -3.037  1.000 19.834 0 35   VAL A HG21 1 c 
ATOM   535  H HG22 . VAL A 1 40  ? 6.735   -9.024  -4.079  1.000 19.792 0 35   VAL A HG22 1 c 
ATOM   536  H HG23 . VAL A 1 40  ? 5.893   -7.965  -3.251  1.000 19.829 0 35   VAL A HG23 1 c 
ATOM   537  N N    . LEU A 1 41  ? 10.355  -8.623  -1.141  1.000 16.819 0 36   LEU A N    1 ? 
ATOM   538  C CA   . LEU A 1 41  ? 11.394  -8.617  -0.121  1.000 17.745 0 36   LEU A CA   1 ? 
ATOM   539  C C    . LEU A 1 41  ? 12.165  -7.300  -0.154  1.000 17.388 0 36   LEU A C    1 ? 
ATOM   540  O O    . LEU A 1 41  ? 12.354  -6.631  0.871   1.000 17.744 0 36   LEU A O    1 ? 
ATOM   541  C CB   . LEU A 1 41  ? 12.349  -9.779  -0.292  1.000 18.172 0 36   LEU A CB   1 ? 
ATOM   542  C CG   . LEU A 1 41  ? 13.577  -9.774  0.617   1.000 20.785 0 36   LEU A CG   1 ? 
ATOM   543  C CD1  . LEU A 1 41  ? 13.171  -9.864  2.051   1.000 22.514 0 36   LEU A CD1  1 ? 
ATOM   544  C CD2  . LEU A 1 41  ? 14.496  -10.943 0.233   1.000 21.642 0 36   LEU A CD2  1 ? 
ATOM   545  H H    . LEU A 1 41  ? 10.349  -9.289  -1.767  1.000 17.170 0 36   LEU A H    1 c 
ATOM   546  H HA   . LEU A 1 41  ? 10.952  -8.694  0.763   1.000 17.616 0 36   LEU A HA   1 c 
ATOM   547  H HB2  . LEU A 1 41  ? 11.850  -10.613 -0.135  1.000 18.633 0 36   LEU A HB2  1 c 
ATOM   548  H HB3  . LEU A 1 41  ? 12.656  -9.787  -1.228  1.000 18.633 0 36   LEU A HB3  1 c 
ATOM   549  H HG   . LEU A 1 41  ? 14.074  -8.928  0.479   1.000 20.720 0 36   LEU A HG   1 c 
ATOM   550  H HD11 . LEU A 1 41  ? 12.709  -9.049  2.311   1.000 21.924 0 36   LEU A HD11 1 c 
ATOM   551  H HD12 . LEU A 1 41  ? 13.962  -9.976  2.606   1.000 21.967 0 36   LEU A HD12 1 c 
ATOM   552  H HD13 . LEU A 1 41  ? 12.579  -10.625 2.175   1.000 21.967 0 36   LEU A HD13 1 c 
ATOM   553  H HD21 . LEU A 1 41  ? 14.775  -10.848 -0.693  1.000 21.388 0 36   LEU A HD21 1 c 
ATOM   554  H HD22 . LEU A 1 41  ? 14.017  -11.782 0.341   1.000 21.388 0 36   LEU A HD22 1 c 
ATOM   555  H HD23 . LEU A 1 41  ? 15.280  -10.943 0.808   1.000 21.388 0 36   LEU A HD23 1 c 
ATOM   556  N N    . LEU A 1 42  ? 12.576  -6.871  -1.352  1.000 17.158 0 37   LEU A N    1 ? 
ATOM   557  C CA   . LEU A 1 42  ? 13.479  -5.735  -1.449  1.000 15.906 0 37   LEU A CA   1 ? 
ATOM   558  C C    . LEU A 1 42  ? 12.777  -4.429  -1.077  1.000 15.931 0 37   LEU A C    1 ? 
ATOM   559  O O    . LEU A 1 42  ? 13.370  -3.561  -0.421  1.000 16.414 0 37   LEU A O    1 ? 
ATOM   560  C CB   . LEU A 1 42  ? 14.100  -5.694  -2.846  1.000 17.701 0 37   LEU A CB   1 ? 
ATOM   561  C CG   . LEU A 1 42  ? 15.033  -6.867  -3.184  1.000 16.209 0 37   LEU A CG   1 ? 
ATOM   562  C CD1  . LEU A 1 42  ? 15.331  -6.833  -4.644  1.000 16.566 0 37   LEU A CD1  1 ? 
ATOM   563  C CD2  . LEU A 1 42  ? 16.304  -6.783  -2.298  1.000 17.793 0 37   LEU A CD2  1 ? 
ATOM   564  H H    . LEU A 1 42  ? 12.296  -7.289  -2.114  1.000 16.932 0 37   LEU A H    1 c 
ATOM   565  H HA   . LEU A 1 42  ? 14.204  -5.875  -0.789  1.000 16.488 0 37   LEU A HA   1 c 
ATOM   566  H HB2  . LEU A 1 42  ? 13.370  -5.676  -3.507  1.000 16.929 0 37   LEU A HB2  1 c 
ATOM   567  H HB3  . LEU A 1 42  ? 14.608  -4.856  -2.934  1.000 16.930 0 37   LEU A HB3  1 c 
ATOM   568  H HG   . LEU A 1 42  ? 14.563  -7.714  -2.978  1.000 16.825 0 37   LEU A HG   1 c 
ATOM   569  H HD11 . LEU A 1 42  ? 14.507  -6.941  -5.147  1.000 16.461 0 37   LEU A HD11 1 c 
ATOM   570  H HD12 . LEU A 1 42  ? 15.943  -7.554  -4.868  1.000 16.458 0 37   LEU A HD12 1 c 
ATOM   571  H HD13 . LEU A 1 42  ? 15.739  -5.980  -4.873  1.000 16.458 0 37   LEU A HD13 1 c 
ATOM   572  H HD21 . LEU A 1 42  ? 16.067  -6.952  -1.371  1.000 17.311 0 37   LEU A HD21 1 c 
ATOM   573  H HD22 . LEU A 1 42  ? 16.696  -5.899  -2.376  1.000 17.320 0 37   LEU A HD22 1 c 
ATOM   574  H HD23 . LEU A 1 42  ? 16.948  -7.449  -2.593  1.000 17.342 0 37   LEU A HD23 1 c 
ATOM   575  N N    . SER A 1 43  ? 11.510  -4.262  -1.497  1.000 16.743 0 38   SER A N    1 ? 
ATOM   576  C CA   . SER A 1 43  ? 10.762  -3.054  -1.182  1.000 15.276 0 38   SER A CA   1 ? 
ATOM   577  C C    . SER A 1 43  ? 10.431  -2.979  0.318   1.000 16.558 0 38   SER A C    1 ? 
ATOM   578  O O    . SER A 1 43  ? 10.474  -1.892  0.906   1.000 16.554 0 38   SER A O    1 ? 
ATOM   579  C CB   . SER A 1 43  ? 9.493   -2.934  -2.019  1.000 16.090 0 38   SER A CB   1 ? 
ATOM   580  O OG   . SER A 1 43  ? 8.725   -1.780  -1.713  1.000 16.136 0 38   SER A OG   1 ? 
ATOM   581  H H    . SER A 1 43  ? 11.108  -4.914  -1.995  1.000 16.211 0 38   SER A H    1 c 
ATOM   582  H HA   . SER A 1 43  ? 11.340  -2.279  -1.400  1.000 15.936 0 38   SER A HA   1 c 
ATOM   583  H HB2  . SER A 1 43  ? 9.739   -2.911  -2.964  1.000 15.914 0 38   SER A HB2  1 c 
ATOM   584  H HB3  . SER A 1 43  ? 8.944   -3.728  -1.877  1.000 15.914 0 38   SER A HB3  1 c 
ATOM   585  H HG   . SER A 1 43  ? 8.039   -1.772  -2.209  0.000 16.120 0 38   SER A HG   1 c 
ATOM   586  N N    . LEU A 1 44  ? 10.149  -4.141  0.935   1.000 16.062 0 39   LEU A N    1 ? 
ATOM   587  C CA   . LEU A 1 44  ? 9.884   -4.162  2.356   1.000 17.240 0 39   LEU A CA   1 ? 
ATOM   588  C C    . LEU A 1 44  ? 11.139  -3.717  3.105   1.000 16.480 0 39   LEU A C    1 ? 
ATOM   589  O O    . LEU A 1 44  ? 11.019  -2.937  4.053   1.000 17.197 0 39   LEU A O    1 ? 
ATOM   590  C CB   . LEU A 1 44  ? 9.394   -5.508  2.859   1.000 17.024 0 39   LEU A CB   1 ? 
ATOM   591  C CG   . LEU A 1 44  ? 7.961   -5.871  2.438   1.000 17.432 0 39   LEU A CG   1 ? 
ATOM   592  C CD1  . LEU A 1 44  ? 7.684   -7.321  2.808   1.000 19.292 0 39   LEU A CD1  1 ? 
ATOM   593  C CD2  . LEU A 1 44  ? 6.975   -4.897  3.122   1.000 19.295 0 39   LEU A CD2  1 ? 
ATOM   594  H H    . LEU A 1 44  ? 10.115  -4.922  0.461   1.000 16.437 0 39   LEU A H    1 c 
ATOM   595  H HA   . LEU A 1 44  ? 9.182   -3.488  2.535   1.000 16.848 0 39   LEU A HA   1 c 
ATOM   596  H HB2  . LEU A 1 44  ? 10.004  -6.204  2.524   1.000 17.186 0 39   LEU A HB2  1 c 
ATOM   597  H HB3  . LEU A 1 44  ? 9.440   -5.507  3.843   1.000 17.174 0 39   LEU A HB3  1 c 
ATOM   598  H HG   . LEU A 1 44  ? 7.881   -5.768  1.455   1.000 18.012 0 39   LEU A HG   1 c 
ATOM   599  H HD11 . LEU A 1 44  ? 8.315   -7.900  2.349   1.000 18.714 0 39   LEU A HD11 1 c 
ATOM   600  H HD12 . LEU A 1 44  ? 6.779   -7.556  2.543   1.000 18.728 0 39   LEU A HD12 1 c 
ATOM   601  H HD13 . LEU A 1 44  ? 7.779   -7.436  3.768   1.000 18.722 0 39   LEU A HD13 1 c 
ATOM   602  H HD21 . LEU A 1 44  ? 7.077   -4.010  2.742   1.000 18.685 0 39   LEU A HD21 1 c 
ATOM   603  H HD22 . LEU A 1 44  ? 7.159   -4.864  4.076   1.000 18.712 0 39   LEU A HD22 1 c 
ATOM   604  H HD23 . LEU A 1 44  ? 6.064   -5.205  2.980   1.000 18.720 0 39   LEU A HD23 1 c 
ATOM   605  N N    . VAL A 1 45  ? 12.321  -4.230  2.717   1.000 16.601 0 40   VAL A N    1 ? 
ATOM   606  C CA   . VAL A 1 45  ? 13.566  -3.859  3.363   1.000 17.618 0 40   VAL A CA   1 ? 
ATOM   607  C C    . VAL A 1 45  ? 13.807  -2.353  3.196   1.000 17.136 0 40   VAL A C    1 ? 
ATOM   608  O O    . VAL A 1 45  ? 14.138  -1.642  4.152   1.000 17.299 0 40   VAL A O    1 ? 
ATOM   609  C CB   . VAL A 1 45  ? 14.742  -4.725  2.858   1.000 19.143 0 40   VAL A CB   1 ? 
ATOM   610  C CG1  . VAL A 1 45  ? 16.088  -4.121  3.227   1.000 18.924 0 40   VAL A CG1  1 ? 
ATOM   611  C CG2  . VAL A 1 45  ? 14.561  -6.167  3.347   1.000 21.262 0 40   VAL A CG2  1 ? 
ATOM   612  H H    . VAL A 1 45  ? 12.344  -4.834  2.030   1.000 16.851 0 40   VAL A H    1 c 
ATOM   613  H HA   . VAL A 1 45  ? 13.461  -4.035  4.318   1.000 17.602 0 40   VAL A HA   1 c 
ATOM   614  H HB   . VAL A 1 45  ? 14.686  -4.738  1.873   1.000 19.165 0 40   VAL A HB   1 c 
ATOM   615  H HG11 . VAL A 1 45  ? 16.077  -3.847  4.160   1.000 18.977 0 40   VAL A HG11 1 c 
ATOM   616  H HG12 . VAL A 1 45  ? 16.266  -3.349  2.664   1.000 18.975 0 40   VAL A HG12 1 c 
ATOM   617  H HG13 . VAL A 1 45  ? 16.787  -4.784  3.094   1.000 18.983 0 40   VAL A HG13 1 c 
ATOM   618  H HG21 . VAL A 1 45  ? 15.270  -6.725  2.984   1.000 20.611 0 40   VAL A HG21 1 c 
ATOM   619  H HG22 . VAL A 1 45  ? 13.700  -6.507  3.052   1.000 20.550 0 40   VAL A HG22 1 c 
ATOM   620  H HG23 . VAL A 1 45  ? 14.600  -6.188  4.318   1.000 20.603 0 40   VAL A HG23 1 c 
ATOM   621  N N    . LEU A 1 46  ? 13.675  -1.823  1.966   1.000 16.420 0 41   LEU A N    1 ? 
ATOM   622  C CA   . LEU A 1 46  ? 13.947  -0.402  1.769   1.000 16.784 0 41   LEU A CA   1 ? 
ATOM   623  C C    . LEU A 1 46  ? 12.980  0.459   2.571   1.000 16.952 0 41   LEU A C    1 ? 
ATOM   624  O O    . LEU A 1 46  ? 13.358  1.485   3.133   1.000 17.424 0 41   LEU A O    1 ? 
ATOM   625  C CB   . LEU A 1 46  ? 13.872  -0.048  0.280   1.000 17.406 0 41   LEU A CB   1 ? 
ATOM   626  C CG   . LEU A 1 46  ? 15.016  -0.511  -0.615  1.000 18.447 0 41   LEU A CG   1 ? 
ATOM   627  C CD1  . LEU A 1 46  ? 14.801  0.134   -2.008  1.000 18.139 0 41   LEU A CD1  1 ? 
ATOM   628  C CD2  . LEU A 1 46  ? 16.352  -0.110  -0.077  1.000 17.748 0 41   LEU A CD2  1 ? 
ATOM   629  H H    . LEU A 1 46  ? 13.422  -2.340  1.256   1.000 16.680 0 41   LEU A H    1 c 
ATOM   630  H HA   . LEU A 1 46  ? 14.863  -0.219  2.097   1.000 16.888 0 41   LEU A HA   1 c 
ATOM   631  H HB2  . LEU A 1 46  ? 13.033  -0.420  -0.078  1.000 17.488 0 41   LEU A HB2  1 c 
ATOM   632  H HB3  . LEU A 1 46  ? 13.801  0.931   0.205   1.000 17.497 0 41   LEU A HB3  1 c 
ATOM   633  H HG   . LEU A 1 46  ? 14.978  -1.497  -0.699  1.000 18.045 0 41   LEU A HG   1 c 
ATOM   634  H HD11 . LEU A 1 46  ? 13.937  -0.135  -2.361  1.000 18.226 0 41   LEU A HD11 1 c 
ATOM   635  H HD12 . LEU A 1 46  ? 15.503  -0.158  -2.613  1.000 18.225 0 41   LEU A HD12 1 c 
ATOM   636  H HD13 . LEU A 1 46  ? 14.829  1.103   -1.925  1.000 18.222 0 41   LEU A HD13 1 c 
ATOM   637  H HD21 . LEU A 1 46  ? 16.580  -0.671  0.683   1.000 17.941 0 41   LEU A HD21 1 c 
ATOM   638  H HD22 . LEU A 1 46  ? 16.323  0.820   0.205   1.000 17.952 0 41   LEU A HD22 1 c 
ATOM   639  H HD23 . LEU A 1 46  ? 17.027  -0.216  -0.769  1.000 17.954 0 41   LEU A HD23 1 c 
ATOM   640  N N    . GLY A 1 47  ? 11.693  0.085   2.584   1.000 16.135 0 42   GLY A N    1 ? 
ATOM   641  C CA   . GLY A 1 47  ? 10.710  0.852   3.329   1.000 17.456 0 42   GLY A CA   1 ? 
ATOM   642  C C    . GLY A 1 47  ? 10.960  0.840   4.840   1.000 16.361 0 42   GLY A C    1 ? 
ATOM   643  O O    . GLY A 1 47  ? 10.750  1.847   5.504   1.000 16.559 0 42   GLY A O    1 ? 
ATOM   644  H H    . GLY A 1 47  ? 11.424  -0.653  2.118   1.000 16.617 0 42   GLY A H    1 c 
ATOM   645  H HA2  . GLY A 1 47  ? 10.723  1.783   3.006   1.000 16.931 0 42   GLY A HA2  1 c 
ATOM   646  H HA3  . GLY A 1 47  ? 9.818   0.485   3.143   1.000 16.909 0 42   GLY A HA3  1 c 
ATOM   647  N N    . PHE A 1 48  ? 11.403  -0.321  5.341   1.000 16.529 0 43   PHE A N    1 ? 
ATOM   648  C CA   . PHE A 1 48  ? 11.756  -0.466  6.749   1.000 17.547 0 43   PHE A CA   1 ? 
ATOM   649  C C    . PHE A 1 48  ? 12.879  0.512   7.078   1.000 17.595 0 43   PHE A C    1 ? 
ATOM   650  O O    . PHE A 1 48  ? 12.793  1.297   8.031   1.000 17.535 0 43   PHE A O    1 ? 
ATOM   651  C CB   . PHE A 1 48  ? 12.110  -1.926  7.014   1.000 18.615 0 43   PHE A CB   1 ? 
ATOM   652  C CG   . PHE A 1 48  ? 12.685  -2.161  8.412   1.000 18.949 0 43   PHE A CG   1 ? 
ATOM   653  C CD1  . PHE A 1 48  ? 11.843  -2.500  9.477   1.000 20.643 0 43   PHE A CD1  1 ? 
ATOM   654  C CD2  . PHE A 1 48  ? 14.056  -2.109  8.618   1.000 18.736 0 43   PHE A CD2  1 ? 
ATOM   655  C CE1  . PHE A 1 48  ? 12.385  -2.693  10.746  1.000 21.015 0 43   PHE A CE1  1 ? 
ATOM   656  C CE2  . PHE A 1 48  ? 14.586  -2.327  9.884   1.000 19.284 0 43   PHE A CE2  1 ? 
ATOM   657  C CZ   . PHE A 1 48  ? 13.742  -2.560  10.940  1.000 19.952 0 43   PHE A CZ   1 ? 
ATOM   658  H H    . PHE A 1 48  ? 11.479  -1.048  4.791   1.000 16.738 0 43   PHE A H    1 c 
ATOM   659  H HA   . PHE A 1 48  ? 10.961  -0.230  7.297   1.000 17.542 0 43   PHE A HA   1 c 
ATOM   660  H HB2  . PHE A 1 48  ? 11.300  -2.471  6.904   1.000 18.436 0 43   PHE A HB2  1 c 
ATOM   661  H HB3  . PHE A 1 48  ? 12.768  -2.217  6.345   1.000 18.422 0 43   PHE A HB3  1 c 
ATOM   662  H HD1  . PHE A 1 48  ? 10.908  -2.531  9.350   1.000 20.298 0 43   PHE A HD1  1 c 
ATOM   663  H HD2  . PHE A 1 48  ? 14.629  -1.893  7.899   1.000 18.939 0 43   PHE A HD2  1 c 
ATOM   664  H HE1  . PHE A 1 48  ? 11.822  -2.886  11.476  1.000 20.638 0 43   PHE A HE1  1 c 
ATOM   665  H HE2  . PHE A 1 48  ? 15.515  -2.251  10.027  1.000 19.349 0 43   PHE A HE2  1 c 
ATOM   666  H HZ   . PHE A 1 48  ? 14.107  -2.741  11.791  1.000 20.035 0 43   PHE A HZ   1 c 
ATOM   667  N N    A VAL A 1 49  ? 13.971  0.481   6.301   0.500 18.435 0 44   VAL A N    1 ? 
ATOM   668  N N    B VAL A 1 49  ? 13.978  0.385   6.333   0.500 17.858 0 44   VAL A N    1 ? 
ATOM   669  C CA   A VAL A 1 49  ? 15.137  1.280   6.659   0.500 18.631 0 44   VAL A CA   1 ? 
ATOM   670  C CA   B VAL A 1 49  ? 15.142  1.217   6.565   0.500 18.187 0 44   VAL A CA   1 ? 
ATOM   671  C C    A VAL A 1 49  ? 14.869  2.764   6.425   0.500 17.829 0 44   VAL A C    1 ? 
ATOM   672  C C    B VAL A 1 49  ? 14.778  2.701   6.478   0.500 17.741 0 44   VAL A C    1 ? 
ATOM   673  O O    A VAL A 1 49  ? 15.373  3.614   7.165   0.500 18.983 0 44   VAL A O    1 ? 
ATOM   674  O O    B VAL A 1 49  ? 15.069  3.474   7.394   0.500 19.480 0 44   VAL A O    1 ? 
ATOM   675  C CB   A VAL A 1 49  ? 16.458  0.851   5.999   0.500 18.846 0 44   VAL A CB   1 ? 
ATOM   676  C CB   B VAL A 1 49  ? 16.225  0.776   5.571   0.500 18.458 0 44   VAL A CB   1 ? 
ATOM   677  C CG1  A VAL A 1 49  ? 16.771  -0.603  6.325   0.500 19.074 0 44   VAL A CG1  1 ? 
ATOM   678  C CG1  B VAL A 1 49  ? 17.371  1.768   5.516   0.500 18.767 0 44   VAL A CG1  1 ? 
ATOM   679  C CG2  A VAL A 1 49  ? 16.471  1.137   4.500   0.500 20.642 0 44   VAL A CG2  1 ? 
ATOM   680  C CG2  B VAL A 1 49  ? 16.715  -0.633  5.878   0.500 18.439 0 44   VAL A CG2  1 ? 
ATOM   681  H H    A VAL A 1 49  ? 13.994  -0.039  5.549   0.500 18.257 0 44   VAL A H    1 c 
ATOM   682  H H    B VAL A 1 49  ? 14.004  -0.238  5.664   0.500 17.861 0 44   VAL A H    1 c 
ATOM   683  H HA   A VAL A 1 49  ? 15.264  1.168   7.622   0.500 18.470 0 44   VAL A HA   1 c 
ATOM   684  H HA   B VAL A 1 49  ? 15.467  1.036   7.468   0.500 18.089 0 44   VAL A HA   1 c 
ATOM   685  H HB   A VAL A 1 49  ? 17.170  1.399   6.404   0.500 19.172 0 44   VAL A HB   1 c 
ATOM   686  H HB   B VAL A 1 49  ? 15.806  0.757   4.678   0.500 18.461 0 44   VAL A HB   1 c 
ATOM   687  H HG11 A VAL A 1 49  ? 16.026  -1.164  6.053   0.500 19.008 0 44   VAL A HG11 1 c 
ATOM   688  H HG11 B VAL A 1 49  ? 17.735  1.893   6.409   0.500 18.700 0 44   VAL A HG11 1 c 
ATOM   689  H HG12 A VAL A 1 49  ? 16.914  -0.697  7.282   0.500 19.015 0 44   VAL A HG12 1 c 
ATOM   690  H HG12 B VAL A 1 49  ? 17.048  2.618   5.175   0.500 18.701 0 44   VAL A HG12 1 c 
ATOM   691  H HG13 A VAL A 1 49  ? 17.573  -0.877  5.850   0.500 19.050 0 44   VAL A HG13 1 c 
ATOM   692  H HG13 B VAL A 1 49  ? 18.067  1.428   4.928   0.500 18.685 0 44   VAL A HG13 1 c 
ATOM   693  H HG21 A VAL A 1 49  ? 17.320  0.853   4.122   0.500 20.082 0 44   VAL A HG21 1 c 
ATOM   694  H HG21 B VAL A 1 49  ? 17.320  -0.927  5.176   0.500 18.443 0 44   VAL A HG21 1 c 
ATOM   695  H HG22 A VAL A 1 49  ? 16.353  2.090   4.350   0.500 20.068 0 44   VAL A HG22 1 c 
ATOM   696  H HG22 B VAL A 1 49  ? 15.957  -1.238  5.926   0.500 18.438 0 44   VAL A HG22 1 c 
ATOM   697  H HG23 A VAL A 1 49  ? 15.748  0.650   4.071   0.500 20.052 0 44   VAL A HG23 1 c 
ATOM   698  H HG23 B VAL A 1 49  ? 17.183  -0.635  6.730   0.500 18.443 0 44   VAL A HG23 1 c 
ATOM   699  N N    . GLU A 1 50  ? 14.035  3.095   5.431   1.000 16.835 0 45   GLU A N    1 ? 
ATOM   700  C CA   . GLU A 1 50  ? 13.612  4.467   5.220   1.000 17.135 0 45   GLU A CA   1 ? 
ATOM   701  C C    . GLU A 1 50  ? 12.757  4.955   6.377   1.000 17.652 0 45   GLU A C    1 ? 
ATOM   702  O O    . GLU A 1 50  ? 12.884  6.094   6.804   1.000 18.325 0 45   GLU A O    1 ? 
ATOM   703  C CB   . GLU A 1 50  ? 12.930  4.650   3.856   1.000 18.205 0 45   GLU A CB   1 ? 
ATOM   704  C CG   . GLU A 1 50  ? 12.457  6.072   3.579   1.000 20.285 0 45   GLU A CG   1 ? 
ATOM   705  C CD   . GLU A 1 50  ? 12.125  6.395   2.122   1.000 19.497 0 45   GLU A CD   1 ? 
ATOM   706  O OE1  . GLU A 1 50  ? 12.893  5.861   1.293   1.000 18.623 0 45   GLU A OE1  1 ? 
ATOM   707  O OE2  . GLU A 1 50  ? 11.171  7.153   1.845   1.000 19.238 0 45   GLU A OE2  1 ? 
ATOM   708  H H    . GLU A 1 50  ? 13.756  2.460   4.837   1.000 17.276 0 45   GLU A H    1 c 
ATOM   709  H HA   . GLU A 1 50  ? 14.428  5.028   5.201   1.000 17.398 0 45   GLU A HA   1 c 
ATOM   710  H HB2  . GLU A 1 50  ? 13.559  4.379   3.156   1.000 18.406 0 45   GLU A HB2  1 c 
ATOM   711  H HB3  . GLU A 1 50  ? 12.157  4.049   3.810   1.000 18.407 0 45   GLU A HB3  1 c 
ATOM   712  H HG2  . GLU A 1 50  ? 11.657  6.248   4.119   1.000 19.603 0 45   GLU A HG2  1 c 
ATOM   713  H HG3  . GLU A 1 50  ? 13.150  6.698   3.880   1.000 19.611 0 45   GLU A HG3  1 c 
ATOM   714  N N    . HIS A 1 51  ? 11.848  4.116   6.865   1.000 18.072 0 46   HIS A N    1 ? 
ATOM   715  C CA   . HIS A 1 51  ? 10.985  4.520   7.962   1.000 18.469 0 46   HIS A CA   1 ? 
ATOM   716  C C    . HIS A 1 51  ? 11.840  4.931   9.180   1.000 19.927 0 46   HIS A C    1 ? 
ATOM   717  O O    . HIS A 1 51  ? 11.598  5.980   9.772   1.000 19.409 0 46   HIS A O    1 ? 
ATOM   718  C CB   . HIS A 1 51  ? 10.003  3.412   8.340   1.000 17.434 0 46   HIS A CB   1 ? 
ATOM   719  C CG   . HIS A 1 51  ? 9.110   3.850   9.452   1.000 18.687 0 46   HIS A CG   1 ? 
ATOM   720  N ND1  . HIS A 1 51  ? 7.955   4.591   9.258   1.000 21.577 0 46   HIS A ND1  1 ? 
ATOM   721  C CD2  . HIS A 1 51  ? 9.270   3.695   10.776  1.000 21.831 0 46   HIS A CD2  1 ? 
ATOM   722  C CE1  . HIS A 1 51  ? 7.425   4.830   10.476  1.000 22.010 0 46   HIS A CE1  1 ? 
ATOM   723  N NE2  . HIS A 1 51  ? 8.214   4.346   11.411  1.000 21.744 0 46   HIS A NE2  1 ? 
ATOM   724  H H    . HIS A 1 51  ? 11.755  3.280   6.509   1.000 18.040 0 46   HIS A H    1 c 
ATOM   725  H HA   . HIS A 1 51  ? 10.469  5.310   7.665   1.000 18.446 0 46   HIS A HA   1 c 
ATOM   726  H HB2  . HIS A 1 51  ? 9.457   3.185   7.556   1.000 17.949 0 46   HIS A HB2  1 c 
ATOM   727  H HB3  . HIS A 1 51  ? 10.507  2.618   8.622   1.000 17.947 0 46   HIS A HB3  1 c 
ATOM   728  H HD1  . HIS A 1 51  ? 7.647   4.862   8.478   0.000 21.580 0 46   HIS A HD1  1 c 
ATOM   729  H HD2  . HIS A 1 51  ? 9.981   3.260   11.203  1.000 21.053 0 46   HIS A HD2  1 c 
ATOM   730  H HE1  . HIS A 1 51  ? 6.631   5.314   10.627  1.000 21.819 0 46   HIS A HE1  1 c 
ATOM   731  H HE2  . HIS A 1 51  ? 8.065   4.386   12.274  0.000 21.630 0 46   HIS A HE2  1 c 
ATOM   732  N N    . PHE A 1 52  ? 12.837  4.106   9.509   1.000 19.649 0 47   PHE A N    1 ? 
ATOM   733  C CA   . PHE A 1 52  ? 13.632  4.301   10.728  1.000 20.235 0 47   PHE A CA   1 ? 
ATOM   734  C C    . PHE A 1 52  ? 14.834  5.218   10.517  1.000 22.813 0 47   PHE A C    1 ? 
ATOM   735  O O    . PHE A 1 52  ? 15.495  5.546   11.496  1.000 23.266 0 47   PHE A O    1 ? 
ATOM   736  C CB   . PHE A 1 52  ? 13.948  2.911   11.299  1.000 22.346 0 47   PHE A CB   1 ? 
ATOM   737  C CG   . PHE A 1 52  ? 12.732  2.199   11.860  1.000 21.233 0 47   PHE A CG   1 ? 
ATOM   738  C CD1  . PHE A 1 52  ? 12.075  2.716   12.977  1.000 22.299 0 47   PHE A CD1  1 ? 
ATOM   739  C CD2  . PHE A 1 52  ? 12.257  1.012   11.320  1.000 21.121 0 47   PHE A CD2  1 ? 
ATOM   740  C CE1  . PHE A 1 52  ? 10.941  2.082   13.482  1.000 25.098 0 47   PHE A CE1  1 ? 
ATOM   741  C CE2  . PHE A 1 52  ? 11.105  0.399   11.784  1.000 22.055 0 47   PHE A CE2  1 ? 
ATOM   742  C CZ   . PHE A 1 52  ? 10.470  0.906   12.921  1.000 24.558 0 47   PHE A CZ   1 ? 
ATOM   743  H H    . PHE A 1 52  ? 13.032  3.398   8.965   1.000 19.852 0 47   PHE A H    1 c 
ATOM   744  H HA   . PHE A 1 52  ? 13.043  4.752   11.386  1.000 20.968 0 47   PHE A HA   1 c 
ATOM   745  H HB2  . PHE A 1 52  ? 14.343  2.360   10.587  1.000 21.582 0 47   PHE A HB2  1 c 
ATOM   746  H HB3  . PHE A 1 52  ? 14.615  3.011   12.013  1.000 21.601 0 47   PHE A HB3  1 c 
ATOM   747  H HD1  . PHE A 1 52  ? 12.383  3.515   13.374  1.000 22.752 0 47   PHE A HD1  1 c 
ATOM   748  H HD2  . PHE A 1 52  ? 12.680  0.663   10.552  1.000 21.391 0 47   PHE A HD2  1 c 
ATOM   749  H HE1  . PHE A 1 52  ? 10.505  2.445   14.236  1.000 24.234 0 47   PHE A HE1  1 c 
ATOM   750  H HE2  . PHE A 1 52  ? 10.812  -0.412  11.399  1.000 22.388 0 47   PHE A HE2  1 c 
ATOM   751  H HZ   . PHE A 1 52  ? 9.701   0.483   13.269  1.000 24.026 0 47   PHE A HZ   1 c 
ATOM   752  N N    . LEU A 1 53  ? 15.060  5.736   9.307   1.000 18.010 0 48   LEU A N    1 ? 
ATOM   753  C CA   . LEU A 1 53  ? 16.109  6.718   9.050   1.000 19.005 0 48   LEU A CA   1 ? 
ATOM   754  C C    . LEU A 1 53  ? 15.518  8.062   8.683   1.000 21.481 0 48   LEU A C    1 ? 
ATOM   755  O O    . LEU A 1 53  ? 16.225  9.037   8.813   1.000 25.835 0 48   LEU A O    1 ? 
ATOM   756  C CB   . LEU A 1 53  ? 17.076  6.264   7.972   1.000 19.312 0 48   LEU A CB   1 ? 
ATOM   757  C CG   . LEU A 1 53  ? 18.049  5.149   8.322   1.000 20.453 0 48   LEU A CG   1 ? 
ATOM   758  C CD1  . LEU A 1 53  ? 18.696  4.561   7.108   1.000 22.573 0 48   LEU A CD1  1 ? 
ATOM   759  C CD2  . LEU A 1 53  ? 19.094  5.650   9.296   1.000 22.233 0 48   LEU A CD2  1 ? 
ATOM   760  H H    . LEU A 1 53  ? 14.553  5.450   8.603   1.000 19.305 0 48   LEU A H    1 c 
ATOM   761  H HA   . LEU A 1 53  ? 16.617  6.842   9.890   1.000 19.368 0 48   LEU A HA   1 c 
ATOM   762  H HB2  . LEU A 1 53  ? 16.546  5.977   7.192   1.000 19.532 0 48   LEU A HB2  1 c 
ATOM   763  H HB3  . LEU A 1 53  ? 17.600  7.047   7.683   1.000 19.553 0 48   LEU A HB3  1 c 
ATOM   764  H HG   . LEU A 1 53  ? 17.537  4.427   8.772   1.000 20.941 0 48   LEU A HG   1 c 
ATOM   765  H HD11 . LEU A 1 53  ? 18.011  4.265   6.487   1.000 21.830 0 48   LEU A HD11 1 c 
ATOM   766  H HD12 . LEU A 1 53  ? 19.248  3.803   7.367   1.000 21.892 0 48   LEU A HD12 1 c 
ATOM   767  H HD13 . LEU A 1 53  ? 19.252  5.232   6.678   1.000 21.879 0 48   LEU A HD13 1 c 
ATOM   768  H HD21 . LEU A 1 53  ? 18.670  5.883   10.139  1.000 21.669 0 48   LEU A HD21 1 c 
ATOM   769  H HD22 . LEU A 1 53  ? 19.532  6.435   8.927   1.000 21.676 0 48   LEU A HD22 1 c 
ATOM   770  H HD23 . LEU A 1 53  ? 19.755  4.954   9.450   1.000 21.683 0 48   LEU A HD23 1 c 
ATOM   771  N N    . ALA A 1 54  ? 14.274  8.162   8.164   1.000 20.522 0 49   ALA A N    1 ? 
ATOM   772  C CA   . ALA A 1 54  ? 13.705  9.434   7.732   1.000 20.040 0 49   ALA A CA   1 ? 
ATOM   773  C C    . ALA A 1 54  ? 12.377  9.753   8.418   1.000 21.967 0 49   ALA A C    1 ? 
ATOM   774  O O    . ALA A 1 54  ? 12.019  10.923  8.539   1.000 26.705 0 49   ALA A O    1 ? 
ATOM   775  C CB   . ALA A 1 54  ? 13.517  9.417   6.238   1.000 19.929 0 49   ALA A CB   1 ? 
ATOM   776  H H    . ALA A 1 54  ? 13.776  7.404   8.058   1.000 20.644 0 49   ALA A H    1 c 
ATOM   777  H HA   . ALA A 1 54  ? 14.348  10.156  7.965   1.000 20.533 0 49   ALA A HA   1 c 
ATOM   778  H HB1  . ALA A 1 54  ? 14.374  9.276   5.801   1.000 19.962 0 49   ALA A HB1  1 c 
ATOM   779  H HB2  . ALA A 1 54  ? 12.910  8.698   5.993   1.000 19.964 0 49   ALA A HB2  1 c 
ATOM   780  H HB3  . ALA A 1 54  ? 13.143  10.265  5.945   1.000 19.972 0 49   ALA A HB3  1 c 
ATOM   781  N N    . VAL A 1 55  ? 11.575  8.740   8.772   1.000 23.703 0 50   VAL A N    1 ? 
ATOM   782  C CA   . VAL A 1 55  ? 10.245  9.027   9.294   1.000 23.313 0 50   VAL A CA   1 ? 
ATOM   783  C C    . VAL A 1 55  ? 10.323  9.148   10.805  1.000 24.870 0 50   VAL A C    1 ? 
ATOM   784  O O    . VAL A 1 55  ? 9.726   10.073  11.371  1.000 30.197 0 50   VAL A O    1 ? 
ATOM   785  C CB   . VAL A 1 55  ? 9.146   8.037   8.863   1.000 26.426 0 50   VAL A CB   1 ? 
ATOM   786  C CG1  . VAL A 1 55  ? 7.809   8.382   9.501   1.000 26.387 0 50   VAL A CG1  1 ? 
ATOM   787  C CG2  . VAL A 1 55  ? 9.013   7.990   7.350   1.000 26.311 0 50   VAL A CG2  1 ? 
ATOM   788  H H    . VAL A 1 55  ? 11.846  7.873   8.681   1.000 23.168 0 50   VAL A H    1 c 
ATOM   789  H HA   . VAL A 1 55  ? 9.984   9.903   8.950   1.000 24.260 0 50   VAL A HA   1 c 
ATOM   790  H HB   . VAL A 1 55  ? 9.415   7.142   9.177   1.000 25.751 0 50   VAL A HB   1 c 
ATOM   791  H HG11 . VAL A 1 55  ? 7.635   9.333   9.398   1.000 26.396 0 50   VAL A HG11 1 c 
ATOM   792  H HG12 . VAL A 1 55  ? 7.831   8.158   10.447  1.000 26.390 0 50   VAL A HG12 1 c 
ATOM   793  H HG13 . VAL A 1 55  ? 7.101   7.876   9.067   1.000 26.396 0 50   VAL A HG13 1 c 
ATOM   794  H HG21 . VAL A 1 55  ? 8.315   7.359   7.105   1.000 26.336 0 50   VAL A HG21 1 c 
ATOM   795  H HG22 . VAL A 1 55  ? 9.856   7.707   6.958   1.000 26.324 0 50   VAL A HG22 1 c 
ATOM   796  H HG23 . VAL A 1 55  ? 8.782   8.873   7.017   1.000 26.316 0 50   VAL A HG23 1 c 
ATOM   797  N N    . ASN A 1 56  ? 11.022  8.226   11.455  1.000 25.701 0 51   ASN A N    1 ? 
ATOM   798  C CA   . ASN A 1 56  ? 11.118  8.159   12.908  1.000 31.026 0 51   ASN A CA   1 ? 
ATOM   799  C C    . ASN A 1 56  ? 12.507  7.661   13.320  1.000 27.196 0 51   ASN A C    1 ? 
ATOM   800  O O    . ASN A 1 56  ? 12.788  6.467   13.290  1.000 25.807 0 51   ASN A O    1 ? 
ATOM   801  C CB   . ASN A 1 56  ? 10.029  7.263   13.475  1.000 33.437 0 51   ASN A CB   1 ? 
ATOM   802  C CG   . ASN A 1 56  ? 10.117  7.190   14.976  1.000 42.255 0 51   ASN A CG   1 ? 
ATOM   803  O OD1  . ASN A 1 56  ? 10.814  8.006   15.589  1.000 42.468 0 51   ASN A OD1  1 ? 
ATOM   804  N ND2  . ASN A 1 56  ? 9.440   6.221   15.566  1.000 42.934 0 51   ASN A ND2  1 ? 
ATOM   805  H H    . ASN A 1 56  ? 11.463  7.591   10.967  1.000 26.544 0 51   ASN A H    1 c 
ATOM   806  H HA   . ASN A 1 56  ? 10.983  9.063   13.271  1.000 29.621 0 51   ASN A HA   1 c 
ATOM   807  H HB2  . ASN A 1 56  ? 9.154   7.615   13.219  1.000 34.699 0 51   ASN A HB2  1 c 
ATOM   808  H HB3  . ASN A 1 56  ? 10.120  6.364   13.101  1.000 34.693 0 51   ASN A HB3  1 c 
ATOM   809  H HD21 . ASN A 1 56  ? 8.965   5.650   15.080  1.000 42.578 0 51   ASN A HD21 1 c 
ATOM   810  H HD22 . ASN A 1 56  ? 9.460   6.142   16.449  1.000 42.688 0 51   ASN A HD22 1 c 
ATOM   811  N N    . ARG A 1 57  ? 13.384  8.625   13.690  1.000 27.705 0 52   ARG A N    1 ? 
ATOM   812  C CA   . ARG A 1 57  ? 14.768  8.369   14.068  1.000 29.424 0 52   ARG A CA   1 ? 
ATOM   813  C C    . ARG A 1 57  ? 14.953  8.200   15.581  1.000 31.178 0 52   ARG A C    1 ? 
ATOM   814  O O    . ARG A 1 57  ? 16.079  8.054   16.055  1.000 31.250 0 52   ARG A O    1 ? 
ATOM   815  C CB   . ARG A 1 57  ? 15.624  9.533   13.547  1.000 27.847 0 52   ARG A CB   1 ? 
ATOM   816  C CG   . ARG A 1 57  ? 15.728  9.618   12.031  1.000 26.896 0 52   ARG A CG   1 ? 
ATOM   817  C CD   . ARG A 1 57  ? 16.552  10.775  11.531  1.000 28.906 0 52   ARG A CD   1 ? 
ATOM   818  N NE   . ARG A 1 57  ? 17.965  10.696  11.919  1.000 28.905 0 52   ARG A NE   1 ? 
ATOM   819  C CZ   . ARG A 1 57  ? 18.932  10.219  11.157  1.000 28.534 0 52   ARG A CZ   1 ? 
ATOM   820  N NH1  . ARG A 1 57  ? 18.616  9.592   10.020  1.000 24.470 0 52   ARG A NH1  1 ? 
ATOM   821  N NH2  . ARG A 1 57  ? 20.203  10.318  11.559  1.000 26.687 0 52   ARG A NH2  1 ? 
ATOM   822  H H    . ARG A 1 57  ? 13.091  9.491   13.706  1.000 27.995 0 52   ARG A H    1 c 
ATOM   823  H HA   . ARG A 1 57  ? 15.065  7.536   13.620  1.000 29.066 0 52   ARG A HA   1 c 
ATOM   824  H HB2  . ARG A 1 57  ? 15.245  10.374  13.882  1.000 27.979 0 52   ARG A HB2  1 c 
ATOM   825  H HB3  . ARG A 1 57  ? 16.528  9.448   13.916  1.000 28.006 0 52   ARG A HB3  1 c 
ATOM   826  H HG2  . ARG A 1 57  ? 16.119  8.784   11.693  1.000 27.564 0 52   ARG A HG2  1 c 
ATOM   827  H HG3  . ARG A 1 57  ? 14.824  9.690   11.655  1.000 27.565 0 52   ARG A HG3  1 c 
ATOM   828  H HD2  . ARG A 1 57  ? 16.486  10.818  10.556  1.000 28.395 0 52   ARG A HD2  1 c 
ATOM   829  H HD3  . ARG A 1 57  ? 16.171  11.603  11.888  1.000 28.425 0 52   ARG A HD3  1 c 
ATOM   830  H HE   . ARG A 1 57  ? 18.181  10.983  12.713  1.000 28.788 0 52   ARG A HE   1 c 
ATOM   831  H HH11 . ARG A 1 57  ? 18.990  9.848   9.260   1.000 25.660 0 52   ARG A HH11 1 c 
ATOM   832  H HH12 . ARG A 1 57  ? 18.037  8.923   10.032  1.000 25.674 0 52   ARG A HH12 1 c 
ATOM   833  H HH21 . ARG A 1 57  ? 20.846  9.965   11.066  1.000 27.227 0 52   ARG A HH21 1 c 
ATOM   834  H HH22 . ARG A 1 57  ? 20.399  10.735  12.314  1.000 27.263 0 52   ARG A HH22 1 c 
ATOM   835  N N    . VAL A 1 58  ? 13.850  8.115   16.343  1.000 34.044 0 53   VAL A N    1 ? 
ATOM   836  C CA   . VAL A 1 58  ? 13.942  7.864   17.771  1.000 31.610 0 53   VAL A CA   1 ? 
ATOM   837  C C    . VAL A 1 58  ? 14.710  6.574   18.043  1.000 32.576 0 53   VAL A C    1 ? 
ATOM   838  O O    . VAL A 1 58  ? 14.334  5.494   17.604  1.000 37.302 0 53   VAL A O    1 ? 
ATOM   839  C CB   . VAL A 1 58  ? 12.541  7.841   18.418  1.000 32.307 0 53   VAL A CB   1 ? 
ATOM   840  C CG1  . VAL A 1 58  ? 12.583  7.352   19.861  1.000 38.570 0 53   VAL A CG1  1 ? 
ATOM   841  C CG2  . VAL A 1 58  ? 11.901  9.213   18.342  1.000 33.261 0 53   VAL A CG2  1 ? 
ATOM   842  H H    . VAL A 1 58  ? 13.024  8.210   15.963  1.000 32.687 0 53   VAL A H    1 c 
ATOM   843  H HA   . VAL A 1 58  ? 14.442  8.603   18.169  1.000 32.387 0 53   VAL A HA   1 c 
ATOM   844  H HB   . VAL A 1 58  ? 11.988  7.213   17.897  1.000 33.479 0 53   VAL A HB   1 c 
ATOM   845  H HG11 . VAL A 1 58  ? 13.300  7.804   20.337  1.000 36.590 0 53   VAL A HG11 1 c 
ATOM   846  H HG12 . VAL A 1 58  ? 12.738  6.392   19.877  1.000 36.573 0 53   VAL A HG12 1 c 
ATOM   847  H HG13 . VAL A 1 58  ? 11.734  7.547   20.294  1.000 36.554 0 53   VAL A HG13 1 c 
ATOM   848  H HG21 . VAL A 1 58  ? 11.004  9.175   18.717  1.000 33.012 0 53   VAL A HG21 1 c 
ATOM   849  H HG22 . VAL A 1 58  ? 11.850  9.501   17.416  1.000 33.034 0 53   VAL A HG22 1 c 
ATOM   850  H HG23 . VAL A 1 58  ? 12.434  9.849   18.848  1.000 32.994 0 53   VAL A HG23 1 c 
ATOM   851  N N    . GLY A 1 59  ? 15.806  6.680   18.808  1.000 33.208 0 74   GLY A N    1 ? 
ATOM   852  C CA   . GLY A 1 59  ? 16.519  5.500   19.254  1.000 33.262 0 74   GLY A CA   1 ? 
ATOM   853  C C    . GLY A 1 59  ? 17.618  5.078   18.276  1.000 30.951 0 74   GLY A C    1 ? 
ATOM   854  O O    . GLY A 1 59  ? 18.345  4.125   18.544  1.000 33.971 0 74   GLY A O    1 ? 
ATOM   855  H H    . GLY A 1 59  ? 16.114  7.504   19.054  1.000 33.052 0 74   GLY A H    1 c 
ATOM   856  H HA2  . GLY A 1 59  ? 16.922  5.686   20.134  1.000 32.726 0 74   GLY A HA2  1 c 
ATOM   857  H HA3  . GLY A 1 59  ? 15.880  4.758   19.368  1.000 32.746 0 74   GLY A HA3  1 c 
ATOM   858  N N    . LEU A 1 60  ? 17.704  5.759   17.123  1.000 31.665 0 75   LEU A N    1 ? 
ATOM   859  C CA   . LEU A 1 60  ? 18.733  5.450   16.131  1.000 30.862 0 75   LEU A CA   1 ? 
ATOM   860  C C    . LEU A 1 60  ? 20.140  5.640   16.710  1.000 29.152 0 75   LEU A C    1 ? 
ATOM   861  O O    . LEU A 1 60  ? 20.441  6.701   17.252  1.000 27.226 0 75   LEU A O    1 ? 
ATOM   862  C CB   . LEU A 1 60  ? 18.540  6.348   14.907  1.000 28.421 0 75   LEU A CB   1 ? 
ATOM   863  C CG   . LEU A 1 60  ? 19.567  6.156   13.785  1.000 28.204 0 75   LEU A CG   1 ? 
ATOM   864  C CD1  . LEU A 1 60  ? 19.525  4.794   13.116  1.000 29.236 0 75   LEU A CD1  1 ? 
ATOM   865  C CD2  . LEU A 1 60  ? 19.370  7.292   12.787  1.000 26.693 0 75   LEU A CD2  1 ? 
ATOM   866  H H    . LEU A 1 60  ? 17.115  6.435   16.948  1.000 31.326 0 75   LEU A H    1 c 
ATOM   867  H HA   . LEU A 1 60  ? 18.627  4.505   15.859  1.000 30.238 0 75   LEU A HA   1 c 
ATOM   868  H HB2  . LEU A 1 60  ? 17.641  6.179   14.540  1.000 28.905 0 75   LEU A HB2  1 c 
ATOM   869  H HB3  . LEU A 1 60  ? 18.574  7.286   15.206  1.000 28.885 0 75   LEU A HB3  1 c 
ATOM   870  H HG   . LEU A 1 60  ? 20.471  6.264   14.178  1.000 28.149 0 75   LEU A HG   1 c 
ATOM   871  H HD11 . LEU A 1 60  ? 19.708  4.104   13.773  1.000 28.968 0 75   LEU A HD11 1 c 
ATOM   872  H HD12 . LEU A 1 60  ? 20.195  4.757   12.413  1.000 28.937 0 75   LEU A HD12 1 c 
ATOM   873  H HD13 . LEU A 1 60  ? 18.644  4.648   12.731  1.000 28.937 0 75   LEU A HD13 1 c 
ATOM   874  H HD21 . LEU A 1 60  ? 19.537  8.143   13.226  1.000 27.141 0 75   LEU A HD21 1 c 
ATOM   875  H HD22 . LEU A 1 60  ? 18.458  7.275   12.451  1.000 27.132 0 75   LEU A HD22 1 c 
ATOM   876  H HD23 . LEU A 1 60  ? 19.989  7.184   12.046  1.000 27.132 0 75   LEU A HD23 1 c 
ATOM   877  N N    . THR A 1 61  ? 21.013  4.638   16.569  1.000 26.615 0 76   THR A N    1 ? 
ATOM   878  C CA   . THR A 1 61  ? 22.387  4.810   17.029  1.000 28.659 0 76   THR A CA   1 ? 
ATOM   879  C C    . THR A 1 61  ? 23.373  4.646   15.885  1.000 29.055 0 76   THR A C    1 ? 
ATOM   880  O O    . THR A 1 61  ? 24.499  5.171   15.963  1.000 28.432 0 76   THR A O    1 ? 
ATOM   881  C CB   . THR A 1 61  ? 22.708  3.846   18.175  1.000 34.904 0 76   THR A CB   1 ? 
ATOM   882  O OG1  . THR A 1 61  ? 22.545  2.509   17.685  1.000 33.817 0 76   THR A OG1  1 ? 
ATOM   883  C CG2  . THR A 1 61  ? 21.882  4.153   19.411  1.000 35.865 0 76   THR A CG2  1 ? 
ATOM   884  H H    . THR A 1 61  ? 20.749  3.838   16.215  1.000 27.679 0 76   THR A H    1 c 
ATOM   885  H HA   . THR A 1 61  ? 22.478  5.723   17.375  1.000 29.356 0 76   THR A HA   1 c 
ATOM   886  H HB   . THR A 1 61  ? 23.656  3.971   18.421  1.000 33.605 0 76   THR A HB   1 c 
ATOM   887  H HG1  . THR A 1 61  ? 21.733  2.401   17.424  0.000 33.790 0 76   THR A HG1  1 c 
ATOM   888  H HG21 . THR A 1 61  ? 22.081  3.506   20.106  1.000 35.563 0 76   THR A HG21 1 c 
ATOM   889  H HG22 . THR A 1 61  ? 20.937  4.107   19.190  1.000 35.513 0 76   THR A HG22 1 c 
ATOM   890  H HG23 . THR A 1 61  ? 22.095  5.046   19.731  1.000 35.563 0 76   THR A HG23 1 c 
ATOM   891  N N    . TYR A 1 62  ? 22.971  3.923   14.826  1.000 26.557 0 77   TYR A N    1 ? 
ATOM   892  C CA   . TYR A 1 62  ? 23.822  3.811   13.648  1.000 25.882 0 77   TYR A CA   1 ? 
ATOM   893  C C    . TYR A 1 62  ? 22.987  3.450   12.418  1.000 24.640 0 77   TYR A C    1 ? 
ATOM   894  O O    . TYR A 1 62  ? 22.971  4.167   11.417  1.000 25.677 0 77   TYR A O    1 ? 
ATOM   895  C CB   . TYR A 1 62  ? 24.918  2.784   13.938  1.000 27.182 0 77   TYR A CB   1 ? 
ATOM   896  C CG   . TYR A 1 62  ? 25.736  2.442   12.707  1.000 27.558 0 77   TYR A CG   1 ? 
ATOM   897  C CD1  . TYR A 1 62  ? 26.545  3.393   12.083  1.000 30.578 0 77   TYR A CD1  1 ? 
ATOM   898  C CD2  . TYR A 1 62  ? 25.696  1.158   12.175  1.000 28.984 0 77   TYR A CD2  1 ? 
ATOM   899  C CE1  . TYR A 1 62  ? 27.277  3.084   10.947  1.000 33.359 0 77   TYR A CE1  1 ? 
ATOM   900  C CE2  . TYR A 1 62  ? 26.385  0.856   11.012  1.000 29.824 0 77   TYR A CE2  1 ? 
ATOM   901  C CZ   . TYR A 1 62  ? 27.195  1.806   10.418  1.000 34.132 0 77   TYR A CZ   1 ? 
ATOM   902  O OH   . TYR A 1 62  ? 27.850  1.387   9.306   1.000 32.587 0 77   TYR A OH   1 ? 
ATOM   903  H H    . TYR A 1 62  ? 22.168  3.487   14.841  1.000 26.981 0 77   TYR A H    1 c 
ATOM   904  H HA   . TYR A 1 62  ? 24.253  4.692   13.486  1.000 26.039 0 77   TYR A HA   1 c 
ATOM   905  H HB2  . TYR A 1 62  ? 25.515  3.144   14.630  1.000 26.993 0 77   TYR A HB2  1 c 
ATOM   906  H HB3  . TYR A 1 62  ? 24.500  1.965   14.285  1.000 27.021 0 77   TYR A HB3  1 c 
ATOM   907  H HD1  . TYR A 1 62  ? 26.593  4.265   12.440  1.000 30.467 0 77   TYR A HD1  1 c 
ATOM   908  H HD2  . TYR A 1 62  ? 25.132  0.509   12.563  1.000 28.886 0 77   TYR A HD2  1 c 
ATOM   909  H HE1  . TYR A 1 62  ? 27.813  3.738   10.531  1.000 32.772 0 77   TYR A HE1  1 c 
ATOM   910  H HE2  . TYR A 1 62  ? 26.350  -0.016  10.659  1.000 30.569 0 77   TYR A HE2  1 c 
ATOM   911  H HH   . TYR A 1 62  ? 28.616  1.071   9.517   0.000 32.580 0 77   TYR A HH   1 c 
ATOM   912  N N    . PHE A 1 63  ? 22.273  2.335   12.540  1.000 27.539 0 78   PHE A N    1 ? 
ATOM   913  C CA   . PHE A 1 63  ? 21.509  1.818   11.413  1.000 28.637 0 78   PHE A CA   1 ? 
ATOM   914  C C    . PHE A 1 63  ? 20.386  0.995   12.007  1.000 25.152 0 78   PHE A C    1 ? 
ATOM   915  O O    . PHE A 1 63  ? 20.630  0.215   12.933  1.000 25.247 0 78   PHE A O    1 ? 
ATOM   916  C CB   . PHE A 1 63  ? 22.424  1.007   10.477  1.000 26.165 0 78   PHE A CB   1 ? 
ATOM   917  C CG   . PHE A 1 63  ? 21.710  0.534   9.226   1.000 26.291 0 78   PHE A CG   1 ? 
ATOM   918  C CD1  . PHE A 1 63  ? 21.644  1.360   8.113   1.000 28.402 0 78   PHE A CD1  1 ? 
ATOM   919  C CD2  . PHE A 1 63  ? 21.059  -0.691  9.200   1.000 29.828 0 78   PHE A CD2  1 ? 
ATOM   920  C CE1  . PHE A 1 63  ? 20.930  0.959   6.990   1.000 27.826 0 78   PHE A CE1  1 ? 
ATOM   921  C CE2  . PHE A 1 63  ? 20.380  -1.096  8.054   1.000 29.206 0 78   PHE A CE2  1 ? 
ATOM   922  C CZ   . PHE A 1 63  ? 20.314  -0.266  6.977   1.000 24.902 0 78   PHE A CZ   1 ? 
ATOM   923  H H    . PHE A 1 63  ? 22.268  1.876   13.331  1.000 27.028 0 78   PHE A H    1 c 
ATOM   924  H HA   . PHE A 1 63  ? 21.124  2.581   10.909  1.000 27.180 0 78   PHE A HA   1 c 
ATOM   925  H HB2  . PHE A 1 63  ? 23.189  1.568   10.217  1.000 26.720 0 78   PHE A HB2  1 c 
ATOM   926  H HB3  . PHE A 1 63  ? 22.766  0.226   10.967  1.000 26.716 0 78   PHE A HB3  1 c 
ATOM   927  H HD1  . PHE A 1 63  ? 22.055  2.210   8.133   1.000 27.753 0 78   PHE A HD1  1 c 
ATOM   928  H HD2  . PHE A 1 63  ? 21.097  -1.259  9.953   1.000 28.770 0 78   PHE A HD2  1 c 
ATOM   929  H HE1  . PHE A 1 63  ? 20.898  1.514   6.227   1.000 27.253 0 78   PHE A HE1  1 c 
ATOM   930  H HE2  . PHE A 1 63  ? 19.944  -1.933  8.034   1.000 28.234 0 78   PHE A HE2  1 c 
ATOM   931  H HZ   . PHE A 1 63  ? 19.858  -0.548  6.201   1.000 26.445 0 78   PHE A HZ   1 c 
ATOM   932  N N    . PRO A 1 64  ? 19.147  1.086   11.476  1.000 21.453 0 79   PRO A N    1 ? 
ATOM   933  C CA   . PRO A 1 64  ? 18.038  0.303   12.008  1.000 21.674 0 79   PRO A CA   1 ? 
ATOM   934  C C    . PRO A 1 64  ? 18.206  -1.149  11.605  1.000 23.695 0 79   PRO A C    1 ? 
ATOM   935  O O    . PRO A 1 64  ? 18.030  -1.493  10.450  1.000 23.613 0 79   PRO A O    1 ? 
ATOM   936  C CB   . PRO A 1 64  ? 16.798  0.912   11.383  1.000 23.274 0 79   PRO A CB   1 ? 
ATOM   937  C CG   . PRO A 1 64  ? 17.318  1.526   10.088  1.000 22.883 0 79   PRO A CG   1 ? 
ATOM   938  C CD   . PRO A 1 64  ? 18.718  2.018   10.416  1.000 22.814 0 79   PRO A CD   1 ? 
ATOM   939  H HA   . PRO A 1 64  ? 18.002  0.391   12.993  1.000 22.303 0 79   PRO A HA   1 c 
ATOM   940  H HB2  . PRO A 1 64  ? 16.116  0.223   11.200  1.000 22.824 0 79   PRO A HB2  1 c 
ATOM   941  H HB3  . PRO A 1 64  ? 16.411  1.602   11.970  1.000 22.807 0 79   PRO A HB3  1 c 
ATOM   942  H HG2  . PRO A 1 64  ? 17.344  0.858   9.372   1.000 22.958 0 79   PRO A HG2  1 c 
ATOM   943  H HG3  . PRO A 1 64  ? 16.748  2.270   9.803   1.000 22.955 0 79   PRO A HG3  1 c 
ATOM   944  H HD2  . PRO A 1 64  ? 19.304  1.961   9.630   1.000 22.601 0 79   PRO A HD2  1 c 
ATOM   945  H HD3  . PRO A 1 64  ? 18.700  2.945   10.742  1.000 22.525 0 79   PRO A HD3  1 c 
ATOM   946  N N    . VAL A 1 65  ? 18.475  -2.019  12.571  1.000 22.233 0 80   VAL A N    1 ? 
ATOM   947  C CA   . VAL A 1 65  ? 18.738  -3.412  12.278  1.000 22.437 0 80   VAL A CA   1 ? 
ATOM   948  C C    . VAL A 1 65  ? 17.455  -4.076  11.795  1.000 22.201 0 80   VAL A C    1 ? 
ATOM   949  O O    . VAL A 1 65  ? 16.415  -3.998  12.458  1.000 22.272 0 80   VAL A O    1 ? 
ATOM   950  C CB   . VAL A 1 65  ? 19.369  -4.111  13.505  1.000 26.426 0 80   VAL A CB   1 ? 
ATOM   951  C CG1  . VAL A 1 65  ? 19.432  -5.619  13.341  1.000 25.528 0 80   VAL A CG1  1 ? 
ATOM   952  C CG2  . VAL A 1 65  ? 20.749  -3.499  13.795  1.000 28.407 0 80   VAL A CG2  1 ? 
ATOM   953  H H    . VAL A 1 65  ? 18.494  -1.738  13.441  1.000 22.717 0 80   VAL A H    1 c 
ATOM   954  H HA   . VAL A 1 65  ? 19.389  -3.443  11.552  1.000 23.028 0 80   VAL A HA   1 c 
ATOM   955  H HB   . VAL A 1 65  ? 18.788  -3.919  14.278  1.000 25.793 0 80   VAL A HB   1 c 
ATOM   956  H HG11 . VAL A 1 65  ? 19.810  -5.836  12.472  1.000 25.785 0 80   VAL A HG11 1 c 
ATOM   957  H HG12 . VAL A 1 65  ? 18.537  -5.993  13.407  1.000 25.770 0 80   VAL A HG12 1 c 
ATOM   958  H HG13 . VAL A 1 65  ? 19.991  -5.998  14.040  1.000 25.785 0 80   VAL A HG13 1 c 
ATOM   959  H HG21 . VAL A 1 65  ? 21.165  -3.972  14.536  1.000 27.787 0 80   VAL A HG21 1 c 
ATOM   960  H HG22 . VAL A 1 65  ? 20.648  -2.561  14.028  1.000 27.732 0 80   VAL A HG22 1 c 
ATOM   961  H HG23 . VAL A 1 65  ? 21.312  -3.577  13.007  1.000 27.756 0 80   VAL A HG23 1 c 
ATOM   962  N N    . ALA A 1 66  ? 17.546  -4.687  10.602  1.000 22.594 0 81   ALA A N    1 ? 
ATOM   963  C CA   . ALA A 1 66  ? 16.448  -5.448  10.029  1.000 22.161 0 81   ALA A CA   1 ? 
ATOM   964  C C    . ALA A 1 66  ? 16.619  -6.928  10.338  1.000 21.994 0 81   ALA A C    1 ? 
ATOM   965  O O    . ALA A 1 66  ? 17.420  -7.644  9.716   1.000 21.578 0 81   ALA A O    1 ? 
ATOM   966  C CB   . ALA A 1 66  ? 16.378  -5.205  8.525   1.000 24.142 0 81   ALA A CB   1 ? 
ATOM   967  H H    . ALA A 1 66  ? 18.326  -4.626  10.129  1.000 22.418 0 81   ALA A H    1 c 
ATOM   968  H HA   . ALA A 1 66  ? 15.597  -5.135  10.445  1.000 22.554 0 81   ALA A HA   1 c 
ATOM   969  H HB1  . ALA A 1 66  ? 16.264  -4.255  8.352   1.000 23.534 0 81   ALA A HB1  1 c 
ATOM   970  H HB2  . ALA A 1 66  ? 17.199  -5.511  8.106   1.000 23.508 0 81   ALA A HB2  1 c 
ATOM   971  H HB3  . ALA A 1 66  ? 15.625  -5.692  8.150   1.000 23.534 0 81   ALA A HB3  1 c 
ATOM   972  N N    . ASP A 1 67  ? 15.864  -7.336  11.359  1.000 21.790 0 82   ASP A N    1 ? 
ATOM   973  C CA   . ASP A 1 67  ? 15.804  -8.717  11.788  1.000 24.679 0 82   ASP A CA   1 ? 
ATOM   974  C C    . ASP A 1 67  ? 14.923  -9.502  10.837  1.000 25.162 0 82   ASP A C    1 ? 
ATOM   975  O O    . ASP A 1 67  ? 13.886  -9.020  10.382  1.000 22.528 0 82   ASP A O    1 ? 
ATOM   976  C CB   . ASP A 1 67  ? 15.265  -8.829  13.205  1.000 26.764 0 82   ASP A CB   1 ? 
ATOM   977  C CG   . ASP A 1 67  ? 16.175  -8.199  14.247  1.000 34.965 0 82   ASP A CG   1 ? 
ATOM   978  O OD1  . ASP A 1 67  ? 17.356  -8.633  14.296  1.000 34.558 0 82   ASP A OD1  1 ? 
ATOM   979  O OD2  . ASP A 1 67  ? 15.733  -7.266  14.950  1.000 37.605 0 82   ASP A OD2  1 ? 
ATOM   980  H H    . ASP A 1 67  ? 15.364  -6.720  11.813  1.000 22.491 0 82   ASP A H    1 c 
ATOM   981  H HA   . ASP A 1 67  ? 16.715  -9.090  11.767  1.000 24.547 0 82   ASP A HA   1 c 
ATOM   982  H HB2  . ASP A 1 67  ? 14.389  -8.392  13.251  1.000 27.993 0 82   ASP A HB2  1 c 
ATOM   983  H HB3  . ASP A 1 67  ? 15.146  -9.776  13.430  1.000 27.940 0 82   ASP A HB3  1 c 
ATOM   984  N N    . LEU A 1 68  ? 15.348  -10.722 10.563  1.000 24.286 0 83   LEU A N    1 ? 
ATOM   985  C CA   . LEU A 1 68  ? 14.560  -11.636 9.762   1.000 24.306 0 83   LEU A CA   1 ? 
ATOM   986  C C    . LEU A 1 68  ? 13.145  -11.782 10.295  1.000 25.676 0 83   LEU A C    1 ? 
ATOM   987  O O    . LEU A 1 68  ? 12.193  -11.826 9.513   1.000 25.030 0 83   LEU A O    1 ? 
ATOM   988  C CB   . LEU A 1 68  ? 15.252  -12.990 9.660   1.000 25.825 0 83   LEU A CB   1 ? 
ATOM   989  C CG   . LEU A 1 68  ? 14.506  -14.014 8.805   1.000 32.235 0 83   LEU A CG   1 ? 
ATOM   990  C CD1  . LEU A 1 68  ? 14.256  -13.516 7.382   1.000 27.873 0 83   LEU A CD1  1 ? 
ATOM   991  C CD2  . LEU A 1 68  ? 15.271  -15.308 8.817   1.000 34.790 0 83   LEU A CD2  1 ? 
ATOM   992  H H    . LEU A 1 68  ? 16.157  -11.003 10.885  1.000 24.507 0 83   LEU A H    1 c 
ATOM   993  H HA   . LEU A 1 68  ? 14.497  -11.246 8.854   1.000 24.865 0 83   LEU A HA   1 c 
ATOM   994  H HB2  . LEU A 1 68  ? 16.148  -12.854 9.276   1.000 26.763 0 83   LEU A HB2  1 c 
ATOM   995  H HB3  . LEU A 1 68  ? 15.355  -13.356 10.569  1.000 26.824 0 83   LEU A HB3  1 c 
ATOM   996  H HG   . LEU A 1 68  ? 13.624  -14.184 9.225   1.000 30.534 0 83   LEU A HG   1 c 
ATOM   997  H HD11 . LEU A 1 68  ? 13.623  -12.778 7.401   1.000 29.031 0 83   LEU A HD11 1 c 
ATOM   998  H HD12 . LEU A 1 68  ? 13.892  -14.238 6.845   1.000 29.077 0 83   LEU A HD12 1 c 
ATOM   999  H HD13 . LEU A 1 68  ? 15.094  -13.213 6.992   1.000 29.077 0 83   LEU A HD13 1 c 
ATOM   1000 H HD21 . LEU A 1 68  ? 15.410  -15.592 9.736   1.000 33.939 0 83   LEU A HD21 1 c 
ATOM   1001 H HD22 . LEU A 1 68  ? 16.132  -15.181 8.386   1.000 33.946 0 83   LEU A HD22 1 c 
ATOM   1002 H HD23 . LEU A 1 68  ? 14.768  -15.989 8.341   1.000 33.974 0 83   LEU A HD23 1 c 
ATOM   1003 N N    . SER A 1 69  ? 12.960  -11.891 11.621  1.000 26.631 0 84   SER A N    1 ? 
ATOM   1004 C CA   . SER A 1 69  ? 11.619  -12.127 12.136  1.000 27.093 0 84   SER A CA   1 ? 
ATOM   1005 C C    . SER A 1 69  ? 10.655  -11.011 11.728  1.000 28.808 0 84   SER A C    1 ? 
ATOM   1006 O O    . SER A 1 69  ? 9.519   -11.315 11.416  1.000 26.670 0 84   SER A O    1 ? 
ATOM   1007 C CB   . SER A 1 69  ? 11.616  -12.345 13.656  1.000 27.289 0 84   SER A CB   1 ? 
ATOM   1008 O OG   . SER A 1 69  ? 12.068  -11.175 14.320  1.000 33.436 0 84   SER A OG   1 ? 
ATOM   1009 H H    . SER A 1 69  ? 13.664  -11.822 12.200  1.000 26.491 0 84   SER A H    1 c 
ATOM   1010 H HA   . SER A 1 69  ? 11.290  -12.964 11.718  1.000 27.321 0 84   SER A HA   1 c 
ATOM   1011 H HB2  . SER A 1 69  ? 10.712  -12.560 13.952  1.000 28.607 0 84   SER A HB2  1 c 
ATOM   1012 H HB3  . SER A 1 69  ? 12.201  -13.094 13.878  1.000 28.607 0 84   SER A HB3  1 c 
ATOM   1013 H HG   . SER A 1 69  ? 12.054  -11.314 15.151  0.000 33.180 0 84   SER A HG   1 c 
ATOM   1014 N N    . ILE A 1 70  ? 11.133  -9.757  11.703  1.000 25.239 0 85   ILE A N    1 ? 
ATOM   1015 C CA   . ILE A 1 70  ? 10.348  -8.569  11.398  1.000 24.078 0 85   ILE A CA   1 ? 
ATOM   1016 C C    . ILE A 1 70  ? 10.031  -8.546  9.894   1.000 22.832 0 85   ILE A C    1 ? 
ATOM   1017 O O    . ILE A 1 70  ? 8.869   -8.394  9.493   1.000 22.607 0 85   ILE A O    1 ? 
ATOM   1018 C CB   . ILE A 1 70  ? 11.166  -7.333  11.831  1.000 28.635 0 85   ILE A CB   1 ? 
ATOM   1019 C CG1  . ILE A 1 70  ? 11.366  -7.259  13.358  1.000 35.537 0 85   ILE A CG1  1 ? 
ATOM   1020 C CG2  . ILE A 1 70  ? 10.603  -6.028  11.295  1.000 29.785 0 85   ILE A CG2  1 ? 
ATOM   1021 C CD1  . ILE A 1 70  ? 10.079  -7.292  14.156  1.000 38.202 0 85   ILE A CD1  1 ? 
ATOM   1022 H H    . ILE A 1 70  ? 12.019  -9.640  11.899  1.000 25.925 0 85   ILE A H    1 c 
ATOM   1023 H HA   . ILE A 1 70  ? 9.513   -8.598  11.902  1.000 24.961 0 85   ILE A HA   1 c 
ATOM   1024 H HB   . ILE A 1 70  ? 12.055  -7.435  11.439  1.000 29.023 0 85   ILE A HB   1 c 
ATOM   1025 H HG12 . ILE A 1 70  ? 11.926  -8.012  13.637  1.000 34.289 0 85   ILE A HG12 1 c 
ATOM   1026 H HG13 . ILE A 1 70  ? 11.848  -6.435  13.573  1.000 34.355 0 85   ILE A HG13 1 c 
ATOM   1027 H HG21 . ILE A 1 70  ? 11.003  -5.280  11.770  1.000 29.496 0 85   ILE A HG21 1 c 
ATOM   1028 H HG22 . ILE A 1 70  ? 9.640   -6.013  11.422  1.000 29.446 0 85   ILE A HG22 1 c 
ATOM   1029 H HG23 . ILE A 1 70  ? 10.804  -5.950  10.347  1.000 29.417 0 85   ILE A HG23 1 c 
ATOM   1030 H HD11 . ILE A 1 70  ? 9.447   -6.649  13.782  1.000 37.305 0 85   ILE A HD11 1 c 
ATOM   1031 H HD12 . ILE A 1 70  ? 10.267  -7.056  15.085  1.000 37.336 0 85   ILE A HD12 1 c 
ATOM   1032 H HD13 . ILE A 1 70  ? 9.689   -8.186  14.124  1.000 37.187 0 85   ILE A HD13 1 c 
ATOM   1033 N N    . ILE A 1 71  ? 11.070  -8.755  9.065   1.000 22.533 0 86   ILE A N    1 ? 
ATOM   1034 C CA   . ILE A 1 71  ? 10.891  -8.675  7.620   1.000 19.712 0 86   ILE A CA   1 ? 
ATOM   1035 C C    . ILE A 1 71  ? 10.039  -9.847  7.129   1.000 22.527 0 86   ILE A C    1 ? 
ATOM   1036 O O    . ILE A 1 71  ? 9.148   -9.670  6.279   1.000 21.042 0 86   ILE A O    1 ? 
ATOM   1037 C CB   . ILE A 1 71  ? 12.239  -8.594  6.886   1.000 21.078 0 86   ILE A CB   1 ? 
ATOM   1038 C CG1  . ILE A 1 71  ? 13.037  -7.350  7.273   1.000 22.489 0 86   ILE A CG1  1 ? 
ATOM   1039 C CG2  . ILE A 1 71  ? 12.055  -8.689  5.368   1.000 21.915 0 86   ILE A CG2  1 ? 
ATOM   1040 C CD1  . ILE A 1 71  ? 12.360  -6.018  6.959   1.000 22.757 0 86   ILE A CD1  1 ? 
ATOM   1041 H H    . ILE A 1 71  ? 11.897  -8.947  9.403   1.000 21.969 0 86   ILE A H    1 c 
ATOM   1042 H HA   . ILE A 1 71  ? 10.400  -7.853  7.428   1.000 21.030 0 86   ILE A HA   1 c 
ATOM   1043 H HB   . ILE A 1 71  ? 12.765  -9.370  7.165   1.000 21.225 0 86   ILE A HB   1 c 
ATOM   1044 H HG12 . ILE A 1 71  ? 13.222  -7.385  8.233   1.000 22.219 0 86   ILE A HG12 1 c 
ATOM   1045 H HG13 . ILE A 1 71  ? 13.897  -7.377  6.806   1.000 22.218 0 86   ILE A HG13 1 c 
ATOM   1046 H HG21 . ILE A 1 71  ? 12.878  -8.422  4.924   1.000 21.676 0 86   ILE A HG21 1 c 
ATOM   1047 H HG22 . ILE A 1 71  ? 11.333  -8.101  5.090   1.000 21.670 0 86   ILE A HG22 1 c 
ATOM   1048 H HG23 . ILE A 1 71  ? 11.840  -9.605  5.121   1.000 21.673 0 86   ILE A HG23 1 c 
ATOM   1049 H HD11 . ILE A 1 71  ? 12.106  -5.991  6.017   1.000 22.667 0 86   ILE A HD11 1 c 
ATOM   1050 H HD12 . ILE A 1 71  ? 12.981  -5.289  7.146   1.000 22.670 0 86   ILE A HD12 1 c 
ATOM   1051 H HD13 . ILE A 1 71  ? 11.563  -5.913  7.512   1.000 22.649 0 86   ILE A HD13 1 c 
ATOM   1052 N N    . ALA A 1 72  ? 10.283  -11.054 7.661   1.000 20.914 0 87   ALA A N    1 ? 
ATOM   1053 C CA   . ALA A 1 72  ? 9.484   -12.210 7.269   1.000 21.452 0 87   ALA A CA   1 ? 
ATOM   1054 C C    . ALA A 1 72  ? 8.024   -12.017 7.671   1.000 20.670 0 87   ALA A C    1 ? 
ATOM   1055 O O    . ALA A 1 72  ? 7.131   -12.482 6.943   1.000 21.819 0 87   ALA A O    1 ? 
ATOM   1056 C CB   . ALA A 1 72  ? 10.083  -13.491 7.846   1.000 24.015 0 87   ALA A CB   1 ? 
ATOM   1057 H H    . ALA A 1 72  ? 10.957  -11.162 8.270   1.000 21.422 0 87   ALA A H    1 c 
ATOM   1058 H HA   . ALA A 1 72  ? 9.514   -12.272 6.274   1.000 21.643 0 87   ALA A HA   1 c 
ATOM   1059 H HB1  . ALA A 1 72  ? 10.989  -13.607 7.514   1.000 23.232 0 87   ALA A HB1  1 c 
ATOM   1060 H HB2  . ALA A 1 72  ? 10.101  -13.435 8.816   1.000 23.232 0 87   ALA A HB2  1 c 
ATOM   1061 H HB3  . ALA A 1 72  ? 9.543   -14.254 7.578   1.000 23.232 0 87   ALA A HB3  1 c 
ATOM   1062 N N    . ALA A 1 73  ? 7.744   -11.374 8.803   1.000 21.113 0 88   ALA A N    1 ? 
ATOM   1063 C CA   . ALA A 1 73  ? 6.351   -11.169 9.180   1.000 23.163 0 88   ALA A CA   1 ? 
ATOM   1064 C C    . ALA A 1 73  ? 5.668   -10.197 8.210   1.000 23.641 0 88   ALA A C    1 ? 
ATOM   1065 O O    . ALA A 1 73  ? 4.529   -10.432 7.817   1.000 23.692 0 88   ALA A O    1 ? 
ATOM   1066 C CB   . ALA A 1 73  ? 6.231   -10.685 10.608  1.000 24.536 0 88   ALA A CB   1 ? 
ATOM   1067 H H    . ALA A 1 73  ? 8.411   -11.067 9.347   1.000 21.462 0 88   ALA A H    1 c 
ATOM   1068 H HA   . ALA A 1 73  ? 5.884   -12.047 9.107   1.000 23.057 0 88   ALA A HA   1 c 
ATOM   1069 H HB1  . ALA A 1 73  ? 6.616   -11.343 11.210  1.000 24.121 0 88   ALA A HB1  1 c 
ATOM   1070 H HB2  . ALA A 1 73  ? 6.705   -9.842  10.709  1.000 24.121 0 88   ALA A HB2  1 c 
ATOM   1071 H HB3  . ALA A 1 73  ? 5.294   -10.554 10.832  1.000 24.121 0 88   ALA A HB3  1 c 
ATOM   1072 N N    . LEU A 1 74  ? 6.351   -9.098  7.847   1.000 22.343 0 89   LEU A N    1 ? 
ATOM   1073 C CA   . LEU A 1 74  ? 5.806   -8.143  6.884   1.000 22.147 0 89   LEU A CA   1 ? 
ATOM   1074 C C    . LEU A 1 74  ? 5.554   -8.857  5.550   1.000 20.137 0 89   LEU A C    1 ? 
ATOM   1075 O O    . LEU A 1 74  ? 4.550   -8.604  4.890   1.000 21.669 0 89   LEU A O    1 ? 
ATOM   1076 C CB   . LEU A 1 74  ? 6.782   -6.987  6.680   1.000 21.852 0 89   LEU A CB   1 ? 
ATOM   1077 C CG   . LEU A 1 74  ? 6.915   -6.023  7.858   1.000 23.673 0 89   LEU A CG   1 ? 
ATOM   1078 C CD1  . LEU A 1 74  ? 8.150   -5.231  7.714   1.000 23.403 0 89   LEU A CD1  1 ? 
ATOM   1079 C CD2  . LEU A 1 74  ? 5.713   -5.099  7.918   1.000 27.228 0 89   LEU A CD2  1 ? 
ATOM   1080 H H    . LEU A 1 74  ? 7.174   -8.936  8.212   1.000 22.588 0 89   LEU A H    1 c 
ATOM   1081 H HA   . LEU A 1 74  ? 4.946   -7.795  7.233   1.000 21.799 0 89   LEU A HA   1 c 
ATOM   1082 H HB2  . LEU A 1 74  ? 7.670   -7.366  6.484   1.000 22.343 0 89   LEU A HB2  1 c 
ATOM   1083 H HB3  . LEU A 1 74  ? 6.493   -6.475  5.890   1.000 22.359 0 89   LEU A HB3  1 c 
ATOM   1084 H HG   . LEU A 1 74  ? 6.963   -6.548  8.698   1.000 23.905 0 89   LEU A HG   1 c 
ATOM   1085 H HD11 . LEU A 1 74  ? 8.921   -5.822  7.737   1.000 23.477 0 89   LEU A HD11 1 c 
ATOM   1086 H HD12 . LEU A 1 74  ? 8.212   -4.591  8.443   1.000 23.483 0 89   LEU A HD12 1 c 
ATOM   1087 H HD13 . LEU A 1 74  ? 8.133   -4.754  6.867   1.000 23.483 0 89   LEU A HD13 1 c 
ATOM   1088 H HD21 . LEU A 1 74  ? 4.906   -5.623  8.056   1.000 26.083 0 89   LEU A HD21 1 c 
ATOM   1089 H HD22 . LEU A 1 74  ? 5.640   -4.606  7.084   1.000 26.087 0 89   LEU A HD22 1 c 
ATOM   1090 H HD23 . LEU A 1 74  ? 5.821   -4.474  8.655   1.000 26.108 0 89   LEU A HD23 1 c 
ATOM   1091 N N    . TYR A 1 75  ? 6.498   -9.699  5.133   1.000 20.003 0 90   TYR A N    1 ? 
ATOM   1092 C CA   . TYR A 1 75  ? 6.419   -10.420 3.867   1.000 19.302 0 90   TYR A CA   1 ? 
ATOM   1093 C C    . TYR A 1 75  ? 5.218   -11.353 3.858   1.000 21.156 0 90   TYR A C    1 ? 
ATOM   1094 O O    . TYR A 1 75  ? 4.473   -11.439 2.872   1.000 21.772 0 90   TYR A O    1 ? 
ATOM   1095 C CB   . TYR A 1 75  ? 7.753   -11.138 3.616   1.000 19.233 0 90   TYR A CB   1 ? 
ATOM   1096 C CG   . TYR A 1 75  ? 7.951   -11.812 2.273   1.000 20.537 0 90   TYR A CG   1 ? 
ATOM   1097 C CD1  . TYR A 1 75  ? 7.449   -13.072 1.987   1.000 21.730 0 90   TYR A CD1  1 ? 
ATOM   1098 C CD2  . TYR A 1 75  ? 8.639   -11.187 1.252   1.000 19.807 0 90   TYR A CD2  1 ? 
ATOM   1099 C CE1  . TYR A 1 75  ? 7.723   -13.707 0.792   1.000 21.985 0 90   TYR A CE1  1 ? 
ATOM   1100 C CE2  . TYR A 1 75  ? 8.879   -11.787 0.041   1.000 19.556 0 90   TYR A CE2  1 ? 
ATOM   1101 C CZ   . TYR A 1 75  ? 8.367   -13.036 -0.229  1.000 21.156 0 90   TYR A CZ   1 ? 
ATOM   1102 O OH   . TYR A 1 75  ? 8.604   -13.668 -1.417  1.000 23.877 0 90   TYR A OH   1 ? 
ATOM   1103 H H    . TYR A 1 75  ? 7.233   -9.829  5.660   1.000 19.898 0 90   TYR A H    1 c 
ATOM   1104 H HA   . TYR A 1 75  ? 6.291   -9.751  3.143   1.000 19.747 0 90   TYR A HA   1 c 
ATOM   1105 H HB2  . TYR A 1 75  ? 8.475   -10.483 3.740   1.000 19.548 0 90   TYR A HB2  1 c 
ATOM   1106 H HB3  . TYR A 1 75  ? 7.865   -11.816 4.319   1.000 19.543 0 90   TYR A HB3  1 c 
ATOM   1107 H HD1  . TYR A 1 75  ? 7.000   -13.550 2.666   1.000 21.475 0 90   TYR A HD1  1 c 
ATOM   1108 H HD2  . TYR A 1 75  ? 8.988   -10.324 1.404   1.000 19.942 0 90   TYR A HD2  1 c 
ATOM   1109 H HE1  . TYR A 1 75  ? 7.359   -14.560 0.626   1.000 21.707 0 90   TYR A HE1  1 c 
ATOM   1110 H HE2  . TYR A 1 75  ? 9.349   -11.321 -0.629  1.000 20.020 0 90   TYR A HE2  1 c 
ATOM   1111 H HH   . TYR A 1 75  ? 7.943   -13.543 -1.951  0.000 23.790 0 90   TYR A HH   1 c 
ATOM   1112 N N    . ALA A 1 76  ? 5.046   -12.081 4.983   1.000 21.272 0 91   ALA A N    1 ? 
ATOM   1113 C CA   . ALA A 1 76  ? 3.883   -12.933 5.142   1.000 22.671 0 91   ALA A CA   1 ? 
ATOM   1114 C C    . ALA A 1 76  ? 2.574   -12.160 5.128   1.000 20.770 0 91   ALA A C    1 ? 
ATOM   1115 O O    . ALA A 1 76  ? 1.614   -12.691 4.556   1.000 25.078 0 91   ALA A O    1 ? 
ATOM   1116 C CB   . ALA A 1 76  ? 3.989   -13.716 6.431   1.000 25.465 0 91   ALA A CB   1 ? 
ATOM   1117 H H    . ALA A 1 76  ? 5.668   -12.046 5.652   1.000 21.550 0 91   ALA A H    1 c 
ATOM   1118 H HA   . ALA A 1 76  ? 3.868   -13.574 4.378   1.000 22.520 0 91   ALA A HA   1 c 
ATOM   1119 H HB1  . ALA A 1 76  ? 4.794   -14.261 6.418   1.000 24.597 0 91   ALA A HB1  1 c 
ATOM   1120 H HB2  . ALA A 1 76  ? 4.028   -13.103 7.184   1.000 24.597 0 91   ALA A HB2  1 c 
ATOM   1121 H HB3  . ALA A 1 76  ? 3.213   -14.294 6.528   1.000 24.579 0 91   ALA A HB3  1 c 
ATOM   1122 N N    . ARG A 1 77  ? 2.500   -10.960 5.715   1.000 20.245 0 92   ARG A N    1 ? 
ATOM   1123 C CA   . ARG A 1 77  ? 1.287   -10.165 5.640   1.000 23.510 0 92   ARG A CA   1 ? 
ATOM   1124 C C    . ARG A 1 77  ? 0.957   -9.849  4.173   1.000 23.888 0 92   ARG A C    1 ? 
ATOM   1125 O O    . ARG A 1 77  ? -0.205  -9.926  3.746   1.000 24.428 0 92   ARG A O    1 ? 
ATOM   1126 C CB   . ARG A 1 77  ? 1.323   -8.876  6.445   1.000 27.333 0 92   ARG A CB   1 ? 
ATOM   1127 C CG   . ARG A 1 77  ? 1.113   -9.072  7.943   1.000 31.785 0 92   ARG A CG   1 ? 
ATOM   1128 C CD   . ARG A 1 77  ? 0.996   -7.737  8.644   1.000 35.622 0 92   ARG A CD   1 ? 
ATOM   1129 N NE   . ARG A 1 77  ? 0.884   -8.027  10.078  1.000 50.440 0 92   ARG A NE   1 ? 
ATOM   1130 C CZ   . ARG A 1 77  ? -0.177  -8.576  10.683  1.000 54.177 0 92   ARG A CZ   1 ? 
ATOM   1131 N NH1  . ARG A 1 77  ? -1.319  -8.733  10.034  1.000 61.262 0 92   ARG A NH1  1 ? 
ATOM   1132 N NH2  . ARG A 1 77  ? -0.093  -8.960  11.945  1.000 50.934 0 92   ARG A NH2  1 ? 
ATOM   1133 H H    . ARG A 1 77  ? 3.219   -10.632 6.175   1.000 21.104 0 92   ARG A H    1 c 
ATOM   1134 H HA   . ARG A 1 77  ? 0.547   -10.715 6.004   1.000 23.590 0 92   ARG A HA   1 c 
ATOM   1135 H HB2  . ARG A 1 77  ? 2.191   -8.440  6.303   1.000 27.326 0 92   ARG A HB2  1 c 
ATOM   1136 H HB3  . ARG A 1 77  ? 0.628   -8.272  6.107   1.000 27.310 0 92   ARG A HB3  1 c 
ATOM   1137 H HG2  . ARG A 1 77  ? 0.293   -9.592  8.092   1.000 31.667 0 92   ARG A HG2  1 c 
ATOM   1138 H HG3  . ARG A 1 77  ? 1.871   -9.570  8.318   1.000 31.557 0 92   ARG A HG3  1 c 
ATOM   1139 H HD2  . ARG A 1 77  ? 1.791   -7.190  8.478   1.000 37.757 0 92   ARG A HD2  1 c 
ATOM   1140 H HD3  . ARG A 1 77  ? 0.205   -7.249  8.339   1.000 37.935 0 92   ARG A HD3  1 c 
ATOM   1141 H HE   . ARG A 1 77  ? 1.565   -7.825  10.581  1.000 47.318 0 92   ARG A HE   1 c 
ATOM   1142 H HH11 . ARG A 1 77  ? -1.878  -9.375  10.287  1.000 58.818 0 92   ARG A HH11 1 c 
ATOM   1143 H HH12 . ARG A 1 77  ? -1.528  -8.201  9.357   1.000 58.526 0 92   ARG A HH12 1 c 
ATOM   1144 H HH21 . ARG A 1 77  ? -0.708  -8.701  12.525  1.000 51.911 0 92   ARG A HH21 1 c 
ATOM   1145 H HH22 . ARG A 1 77  ? 0.578   -9.476  12.203  1.000 51.911 0 92   ARG A HH22 1 c 
ATOM   1146 N N    . PHE A 1 78  ? 1.945   -9.388  3.412   1.000 22.989 0 93   PHE A N    1 ? 
ATOM   1147 C CA   . PHE A 1 78  ? 1.695   -9.082  2.020   1.000 21.684 0 93   PHE A CA   1 ? 
ATOM   1148 C C    . PHE A 1 78  ? 1.239   -10.319 1.251   1.000 22.248 0 93   PHE A C    1 ? 
ATOM   1149 O O    . PHE A 1 78  ? 0.274   -10.249 0.495   1.000 22.775 0 93   PHE A O    1 ? 
ATOM   1150 C CB   . PHE A 1 78  ? 2.914   -8.408  1.393   1.000 20.140 0 93   PHE A CB   1 ? 
ATOM   1151 C CG   . PHE A 1 78  ? 2.659   -7.888  -0.021  1.000 19.606 0 93   PHE A CG   1 ? 
ATOM   1152 C CD1  . PHE A 1 78  ? 2.012   -6.682  -0.220  1.000 20.977 0 93   PHE A CD1  1 ? 
ATOM   1153 C CD2  . PHE A 1 78  ? 3.025   -8.646  -1.137  1.000 21.859 0 93   PHE A CD2  1 ? 
ATOM   1154 C CE1  . PHE A 1 78  ? 1.809   -6.184  -1.494  1.000 21.554 0 93   PHE A CE1  1 ? 
ATOM   1155 C CE2  . PHE A 1 78  ? 2.786   -8.146  -2.412  1.000 20.110 0 93   PHE A CE2  1 ? 
ATOM   1156 C CZ   . PHE A 1 78  ? 2.155   -6.951  -2.585  1.000 18.955 0 93   PHE A CZ   1 ? 
ATOM   1157 H H    . PHE A 1 78  ? 2.780   -9.258  3.760   1.000 22.863 0 93   PHE A H    1 c 
ATOM   1158 H HA   . PHE A 1 78  ? 0.950   -8.425  1.992   1.000 21.774 0 93   PHE A HA   1 c 
ATOM   1159 H HB2  . PHE A 1 78  ? 3.186   -7.657  1.966   1.000 20.358 0 93   PHE A HB2  1 c 
ATOM   1160 H HB3  . PHE A 1 78  ? 3.653   -9.056  1.367   1.000 20.358 0 93   PHE A HB3  1 c 
ATOM   1161 H HD1  . PHE A 1 78  ? 1.770   -6.158  0.528   1.000 20.767 0 93   PHE A HD1  1 c 
ATOM   1162 H HD2  . PHE A 1 78  ? 3.455   -9.479  -1.025  1.000 20.893 0 93   PHE A HD2  1 c 
ATOM   1163 H HE1  . PHE A 1 78  ? 1.364   -5.360  -1.615  1.000 20.773 0 93   PHE A HE1  1 c 
ATOM   1164 H HE2  . PHE A 1 78  ? 3.036   -8.655  -3.167  1.000 20.226 0 93   PHE A HE2  1 c 
ATOM   1165 H HZ   . PHE A 1 78  ? 2.004   -6.622  -3.456  1.000 19.831 0 93   PHE A HZ   1 c 
ATOM   1166 N N    . THR A 1 79  ? 2.004   -11.390 1.281   1.000 21.207 0 94   THR A N    1 ? 
ATOM   1167 C CA   . THR A 1 79  ? 1.705   -12.508 0.401   1.000 24.007 0 94   THR A CA   1 ? 
ATOM   1168 C C    . THR A 1 79  ? 0.365   -13.127 0.787   1.000 26.170 0 94   THR A C    1 ? 
ATOM   1169 O O    . THR A 1 79  ? -0.384  -13.564 -0.109  1.000 26.985 0 94   THR A O    1 ? 
ATOM   1170 C CB   . THR A 1 79  ? 2.866   -13.503 0.331   1.000 26.379 0 94   THR A CB   1 ? 
ATOM   1171 O OG1  . THR A 1 79  ? 2.976   -14.011 1.653   1.000 29.235 0 94   THR A OG1  1 ? 
ATOM   1172 C CG2  . THR A 1 79  ? 4.160   -12.859 -0.136  1.000 27.405 0 94   THR A CG2  1 ? 
ATOM   1173 H H    . THR A 1 79  ? 2.715   -11.441 1.854   1.000 22.145 0 94   THR A H    1 c 
ATOM   1174 H HA   . THR A 1 79  ? 1.600   -12.137 -0.502  1.000 24.217 0 94   THR A HA   1 c 
ATOM   1175 H HB   . THR A 1 79  ? 2.632   -14.240 -0.282  1.000 26.751 0 94   THR A HB   1 c 
ATOM   1176 H HG1  . THR A 1 79  ? 3.138   -13.369 2.201   0.000 29.180 0 94   THR A HG1  1 c 
ATOM   1177 H HG21 . THR A 1 79  ? 4.863   -13.530 -0.167  1.000 27.071 0 94   THR A HG21 1 c 
ATOM   1178 H HG22 . THR A 1 79  ? 4.415   -12.153 0.478   1.000 26.986 0 94   THR A HG22 1 c 
ATOM   1179 H HG23 . THR A 1 79  ? 4.033   -12.484 -1.024  1.000 27.071 0 94   THR A HG23 1 c 
ATOM   1180 N N    . ALA A 1 80  ? 0.020   -13.090 2.098   1.000 29.358 0 95   ALA A N    1 ? 
ATOM   1181 C CA   . ALA A 1 80  ? -1.273  -13.592 2.552   1.000 31.775 0 95   ALA A CA   1 ? 
ATOM   1182 C C    . ALA A 1 80  ? -2.409  -12.730 2.014   1.000 30.229 0 95   ALA A C    1 ? 
ATOM   1183 O O    . ALA A 1 80  ? -3.440  -13.280 1.605   1.000 32.059 0 95   ALA A O    1 ? 
ATOM   1184 C CB   . ALA A 1 80  ? -1.331  -13.703 4.058   1.000 33.654 0 95   ALA A CB   1 ? 
ATOM   1185 H H    . ALA A 1 80  ? 0.606   -12.755 2.714   1.000 28.959 0 95   ALA A H    1 c 
ATOM   1186 H HA   . ALA A 1 80  ? -1.387  -14.506 2.170   1.000 31.286 0 95   ALA A HA   1 c 
ATOM   1187 H HB1  . ALA A 1 80  ? -0.643  -14.316 4.368   1.000 33.085 0 95   ALA A HB1  1 c 
ATOM   1188 H HB2  . ALA A 1 80  ? -1.185  -12.829 4.456   1.000 33.085 0 95   ALA A HB2  1 c 
ATOM   1189 H HB3  . ALA A 1 80  ? -2.203  -14.038 4.328   1.000 33.085 0 95   ALA A HB3  1 c 
ATOM   1190 N N    . GLN A 1 81  ? -2.248  -11.406 2.058   1.000 25.407 0 96   GLN A N    1 ? 
ATOM   1191 C CA   . GLN A 1 81  ? -3.284  -10.489 1.611   1.000 27.796 0 96   GLN A CA   1 ? 
ATOM   1192 C C    . GLN A 1 81  ? -3.554  -10.722 0.112   1.000 26.682 0 96   GLN A C    1 ? 
ATOM   1193 O O    . GLN A 1 81  ? -4.707  -10.709 -0.321  1.000 31.513 0 96   GLN A O    1 ? 
ATOM   1194 C CB   . GLN A 1 81  ? -2.833  -9.050  1.866   1.000 27.765 0 96   GLN A CB   1 ? 
ATOM   1195 C CG   . GLN A 1 81  ? -2.985  -8.549  3.307   1.000 32.496 0 96   GLN A CG   1 ? 
ATOM   1196 C CD   . GLN A 1 81  ? -2.523  -7.122  3.521   1.000 34.348 0 96   GLN A CD   1 ? 
ATOM   1197 O OE1  . GLN A 1 81  ? -2.713  -6.236  2.663   1.000 32.836 0 96   GLN A OE1  1 ? 
ATOM   1198 N NE2  . GLN A 1 81  ? -1.961  -6.869  4.703   1.000 34.317 0 96   GLN A NE2  1 ? 
ATOM   1199 H H    . GLN A 1 81  ? -1.467  -11.062 2.385   1.000 27.087 0 96   GLN A H    1 c 
ATOM   1200 H HA   . GLN A 1 81  ? -4.112  -10.674 2.122   1.000 27.104 0 96   GLN A HA   1 c 
ATOM   1201 H HB2  . GLN A 1 81  ? -1.891  -8.972  1.607   1.000 28.788 0 96   GLN A HB2  1 c 
ATOM   1202 H HB3  . GLN A 1 81  ? -3.345  -8.462  1.276   1.000 28.866 0 96   GLN A HB3  1 c 
ATOM   1203 H HG2  . GLN A 1 81  ? -3.929  -8.608  3.567   1.000 31.761 0 96   GLN A HG2  1 c 
ATOM   1204 H HG3  . GLN A 1 81  ? -2.479  -9.136  3.906   1.000 31.743 0 96   GLN A HG3  1 c 
ATOM   1205 H HE21 . GLN A 1 81  ? -2.071  -7.432  5.380   1.000 34.290 0 96   GLN A HE21 1 c 
ATOM   1206 H HE22 . GLN A 1 81  ? -1.478  -6.132  4.811   1.000 34.318 0 96   GLN A HE22 1 c 
ATOM   1207 N N    . ILE A 1 82  ? -2.503  -10.940 -0.684  1.000 23.970 0 97   ILE A N    1 ? 
ATOM   1208 C CA   . ILE A 1 82  ? -2.657  -11.030 -2.144  1.000 23.053 0 97   ILE A CA   1 ? 
ATOM   1209 C C    . ILE A 1 82  ? -3.222  -12.403 -2.493  1.000 23.707 0 97   ILE A C    1 ? 
ATOM   1210 O O    . ILE A 1 82  ? -4.195  -12.499 -3.246  1.000 25.333 0 97   ILE A O    1 ? 
ATOM   1211 C CB   . ILE A 1 82  ? -1.316  -10.764 -2.885  1.000 23.120 0 97   ILE A CB   1 ? 
ATOM   1212 C CG1  . ILE A 1 82  ? -0.774  -9.374  -2.594  1.000 23.641 0 97   ILE A CG1  1 ? 
ATOM   1213 C CG2  . ILE A 1 82  ? -1.375  -11.010 -4.396  1.000 25.165 0 97   ILE A CG2  1 ? 
ATOM   1214 C CD1  . ILE A 1 82  ? -1.754  -8.215  -2.730  1.000 22.381 0 97   ILE A CD1  1 ? 
ATOM   1215 H H    . ILE A 1 82  ? -1.669  -11.032 -0.321  1.000 24.408 0 97   ILE A H    1 c 
ATOM   1216 H HA   . ILE A 1 82  ? -3.302  -10.354 -2.427  1.000 23.418 0 97   ILE A HA   1 c 
ATOM   1217 H HB   . ILE A 1 82  ? -0.667  -11.398 -2.521  1.000 23.577 0 97   ILE A HB   1 c 
ATOM   1218 H HG12 . ILE A 1 82  ? -0.423  -9.369  -1.682  1.000 23.228 0 97   ILE A HG12 1 c 
ATOM   1219 H HG13 . ILE A 1 82  ? -0.020  -9.208  -3.196  1.000 23.246 0 97   ILE A HG13 1 c 
ATOM   1220 H HG21 . ILE A 1 82  ? -0.534  -10.743 -4.803  1.000 24.490 0 97   ILE A HG21 1 c 
ATOM   1221 H HG22 . ILE A 1 82  ? -2.100  -10.491 -4.783  1.000 24.533 0 97   ILE A HG22 1 c 
ATOM   1222 H HG23 . ILE A 1 82  ? -1.528  -11.954 -4.568  1.000 24.527 0 97   ILE A HG23 1 c 
ATOM   1223 H HD11 . ILE A 1 82  ? -2.232  -8.290  -3.578  1.000 22.746 0 97   ILE A HD11 1 c 
ATOM   1224 H HD12 . ILE A 1 82  ? -1.264  -7.371  -2.708  1.000 22.746 0 97   ILE A HD12 1 c 
ATOM   1225 H HD13 . ILE A 1 82  ? -2.395  -8.235  -1.994  1.000 22.750 0 97   ILE A HD13 1 c 
ATOM   1226 N N    . ARG A 1 83  ? -2.648  -13.470 -1.927  1.000 26.468 0 98   ARG A N    1 ? 
ATOM   1227 C CA   . ARG A 1 83  ? -3.006  -14.830 -2.324  1.000 30.662 0 98   ARG A CA   1 ? 
ATOM   1228 C C    . ARG A 1 83  ? -4.430  -15.134 -1.880  1.000 30.806 0 98   ARG A C    1 ? 
ATOM   1229 O O    . ARG A 1 83  ? -5.165  -15.816 -2.601  1.000 33.332 0 98   ARG A O    1 ? 
ATOM   1230 C CB   . ARG A 1 83  ? -2.019  -15.897 -1.836  1.000 35.013 0 98   ARG A CB   1 ? 
ATOM   1231 C CG   . ARG A 1 83  ? -0.664  -15.777 -2.533  1.000 40.045 0 98   ARG A CG   1 ? 
ATOM   1232 C CD   . ARG A 1 83  ? 0.417   -16.840 -2.213  1.000 42.135 0 98   ARG A CD   1 ? 
ATOM   1233 N NE   . ARG A 1 83  ? 1.710   -16.370 -2.711  1.000 48.306 0 98   ARG A NE   1 ? 
ATOM   1234 C CZ   . ARG A 1 83  ? 2.940   -16.462 -2.149  1.000 61.641 0 98   ARG A CZ   1 ? 
ATOM   1235 N NH1  . ARG A 1 83  ? 3.180   -17.215 -1.081  1.000 61.904 0 98   ARG A NH1  1 ? 
ATOM   1236 N NH2  . ARG A 1 83  ? 3.967   -15.813 -2.693  1.000 57.565 0 98   ARG A NH2  1 ? 
ATOM   1237 H H    . ARG A 1 83  ? -2.013  -13.352 -1.281  1.000 26.603 0 98   ARG A H    1 c 
ATOM   1238 H HA   . ARG A 1 83  ? -2.991  -14.863 -3.314  1.000 30.544 0 98   ARG A HA   1 c 
ATOM   1239 H HB2  . ARG A 1 83  ? -1.893  -15.804 -0.868  1.000 35.027 0 98   ARG A HB2  1 c 
ATOM   1240 H HB3  . ARG A 1 83  ? -2.392  -16.788 -2.010  1.000 35.008 0 98   ARG A HB3  1 c 
ATOM   1241 H HG2  . ARG A 1 83  ? -0.819  -15.785 -3.502  1.000 39.196 0 98   ARG A HG2  1 c 
ATOM   1242 H HG3  . ARG A 1 83  ? -0.291  -14.893 -2.325  1.000 39.182 0 98   ARG A HG3  1 c 
ATOM   1243 H HD2  . ARG A 1 83  ? 0.471   -16.984 -1.247  1.000 43.225 0 98   ARG A HD2  1 c 
ATOM   1244 H HD3  . ARG A 1 83  ? 0.190   -17.689 -2.643  1.000 43.080 0 98   ARG A HD3  1 c 
ATOM   1245 H HE   . ARG A 1 83  ? 1.692   -15.973 -3.486  1.000 49.605 0 98   ARG A HE   1 c 
ATOM   1246 H HH11 . ARG A 1 83  ? 3.856   -17.018 -0.545  1.000 61.690 0 98   ARG A HH11 1 c 
ATOM   1247 H HH12 . ARG A 1 83  ? 2.663   -17.912 -0.909  1.000 61.491 0 98   ARG A HH12 1 c 
ATOM   1248 H HH21 . ARG A 1 83  ? 4.785   -15.942 -2.382  1.000 58.797 0 98   ARG A HH21 1 c 
ATOM   1249 H HH22 . ARG A 1 83  ? 3.831   -15.254 -3.365  1.000 58.628 0 98   ARG A HH22 1 c 
ATOM   1250 N N    . GLY A 1 84  ? -4.818  -14.577 -0.740  1.000 27.599 0 99   GLY A N    1 ? 
ATOM   1251 C CA   . GLY A 1 84  ? -6.171  -14.706 -0.223  1.000 30.187 0 99   GLY A CA   1 ? 
ATOM   1252 C C    . GLY A 1 84  ? -7.236  -13.996 -1.063  1.000 35.227 0 99   GLY A C    1 ? 
ATOM   1253 O O    . GLY A 1 84  ? -8.349  -14.507 -1.167  1.000 31.896 0 99   GLY A O    1 ? 
ATOM   1254 H H    . GLY A 1 84  ? -4.211  -14.100 -0.251  1.000 28.904 0 99   GLY A H    1 c 
ATOM   1255 H HA2  . GLY A 1 84  ? -6.394  -15.664 -0.166  1.000 30.582 0 99   GLY A HA2  1 c 
ATOM   1256 H HA3  . GLY A 1 84  ? -6.191  -14.342 0.693   1.000 30.582 0 99   GLY A HA3  1 c 
ATOM   1257 N N    . ALA A 1 85  ? -6.916  -12.828 -1.652  1.000 26.308 0 100  ALA A N    1 ? 
ATOM   1258 C CA   . ALA A 1 85  ? -7.911  -12.000 -2.322  1.000 26.074 0 100  ALA A CA   1 ? 
ATOM   1259 C C    . ALA A 1 85  ? -7.988  -12.279 -3.826  1.000 25.885 0 100  ALA A C    1 ? 
ATOM   1260 O O    . ALA A 1 85  ? -8.988  -11.905 -4.433  1.000 26.872 0 100  ALA A O    1 ? 
ATOM   1261 C CB   . ALA A 1 85  ? -7.627  -10.526 -2.064  1.000 27.892 0 100  ALA A CB   1 ? 
ATOM   1262 H H    . ALA A 1 85  ? -6.050  -12.536 -1.625  1.000 28.158 0 100  ALA A H    1 c 
ATOM   1263 H HA   . ALA A 1 85  ? -8.801  -12.218 -1.931  1.000 26.481 0 100  ALA A HA   1 c 
ATOM   1264 H HB1  . ALA A 1 85  ? -7.660  -10.349 -1.109  1.000 27.344 0 100  ALA A HB1  1 c 
ATOM   1265 H HB2  . ALA A 1 85  ? -6.745  -10.299 -2.403  1.000 27.344 0 100  ALA A HB2  1 c 
ATOM   1266 H HB3  . ALA A 1 85  ? -8.294  -9.981  -2.514  1.000 27.344 0 100  ALA A HB3  1 c 
ATOM   1267 N N    . VAL A 1 86  ? -6.916  -12.833 -4.401  1.000 27.548 0 101  VAL A N    1 ? 
ATOM   1268 C CA   . VAL A 1 86  ? -6.813  -13.140 -5.816  1.000 27.775 0 101  VAL A CA   1 ? 
ATOM   1269 C C    . VAL A 1 86  ? -6.792  -14.666 -5.977  1.000 32.341 0 101  VAL A C    1 ? 
ATOM   1270 O O    . VAL A 1 86  ? -5.762  -15.335 -5.851  1.000 37.525 0 101  VAL A O    1 ? 
ATOM   1271 C CB   . VAL A 1 86  ? -5.558  -12.538 -6.480  1.000 25.923 0 101  VAL A CB   1 ? 
ATOM   1272 C CG1  . VAL A 1 86  ? -5.554  -12.819 -7.984  1.000 27.172 0 101  VAL A CG1  1 ? 
ATOM   1273 C CG2  . VAL A 1 86  ? -5.373  -11.050 -6.219  1.000 24.303 0 101  VAL A CG2  1 ? 
ATOM   1274 H H    . VAL A 1 86  ? -6.197  -13.029 -3.873  1.000 27.187 0 101  VAL A H    1 c 
ATOM   1275 H HA   . VAL A 1 86  ? -7.602  -12.786 -6.271  1.000 28.195 0 101  VAL A HA   1 c 
ATOM   1276 H HB   . VAL A 1 86  ? -4.778  -13.000 -6.092  1.000 26.249 0 101  VAL A HB   1 c 
ATOM   1277 H HG11 . VAL A 1 86  ? -6.404  -12.547 -8.368  1.000 26.799 0 101  VAL A HG11 1 c 
ATOM   1278 H HG12 . VAL A 1 86  ? -5.419  -13.770 -8.139  1.000 26.819 0 101  VAL A HG12 1 c 
ATOM   1279 H HG13 . VAL A 1 86  ? -4.834  -12.320 -8.406  1.000 26.776 0 101  VAL A HG13 1 c 
ATOM   1280 H HG21 . VAL A 1 86  ? -4.579  -10.735 -6.682  1.000 24.752 0 101  VAL A HG21 1 c 
ATOM   1281 H HG22 . VAL A 1 86  ? -5.272  -10.897 -5.264  1.000 24.779 0 101  VAL A HG22 1 c 
ATOM   1282 H HG23 . VAL A 1 86  ? -6.150  -10.565 -6.543  1.000 24.768 0 101  VAL A HG23 1 c 
ATOM   1283 N N    . ASP A 1 87  ? -7.907  -15.206 -6.425  1.000 32.818 0 102  ASP A N    1 ? 
ATOM   1284 C CA   . ASP A 1 87  ? -7.994  -16.610 -6.751  1.000 34.127 0 102  ASP A CA   1 ? 
ATOM   1285 C C    . ASP A 1 87  ? -7.615  -16.872 -8.209  1.000 28.633 0 102  ASP A C    1 ? 
ATOM   1286 O O    . ASP A 1 87  ? -8.432  -16.743 -9.107  1.000 29.923 0 102  ASP A O    1 ? 
ATOM   1287 C CB   . ASP A 1 87  ? -9.399  -17.078 -6.427  1.000 37.158 0 102  ASP A CB   1 ? 
ATOM   1288 C CG   . ASP A 1 87  ? -9.642  -18.559 -6.631  1.000 39.843 0 102  ASP A CG   1 ? 
ATOM   1289 O OD1  . ASP A 1 87  ? -8.695  -19.256 -7.062  1.000 35.765 0 102  ASP A OD1  1 ? 
ATOM   1290 O OD2  . ASP A 1 87  ? -10.783 -18.979 -6.364  1.000 40.634 0 102  ASP A OD2  1 ? 
ATOM   1291 H H    . ASP A 1 87  ? -8.649  -14.683 -6.532  1.000 32.965 0 102  ASP A H    1 c 
ATOM   1292 H HA   . ASP A 1 87  ? -7.376  -17.106 -6.168  1.000 33.327 0 102  ASP A HA   1 c 
ATOM   1293 H HB2  . ASP A 1 87  ? -9.592  -16.863 -5.491  1.000 37.019 0 102  ASP A HB2  1 c 
ATOM   1294 H HB3  . ASP A 1 87  ? -10.034 -16.583 -6.986  1.000 36.964 0 102  ASP A HB3  1 c 
ATOM   1295 N N    . LEU A 1 88  ? -6.397  -17.363 -8.435  1.000 31.479 0 103  LEU A N    1 ? 
ATOM   1296 C CA   . LEU A 1 88  ? -5.896  -17.612 -9.780  1.000 29.676 0 103  LEU A CA   1 ? 
ATOM   1297 C C    . LEU A 1 88  ? -6.739  -18.596 -10.583 1.000 33.867 0 103  LEU A C    1 ? 
ATOM   1298 O O    . LEU A 1 88  ? -6.756  -18.510 -11.814 1.000 33.574 0 103  LEU A O    1 ? 
ATOM   1299 C CB   . LEU A 1 88  ? -4.455  -18.094 -9.680  1.000 31.387 0 103  LEU A CB   1 ? 
ATOM   1300 C CG   . LEU A 1 88  ? -3.429  -17.048 -9.255  1.000 34.265 0 103  LEU A CG   1 ? 
ATOM   1301 C CD1  . LEU A 1 88  ? -2.024  -17.634 -9.173  1.000 38.345 0 103  LEU A CD1  1 ? 
ATOM   1302 C CD2  . LEU A 1 88  ? -3.435  -15.894 -10.255 1.000 34.072 0 103  LEU A CD2  1 ? 
ATOM   1303 H H    . LEU A 1 88  ? -5.853  -17.548 -7.724  1.000 30.434 0 103  LEU A H    1 c 
ATOM   1304 H HA   . LEU A 1 88  ? -5.910  -16.750 -10.265 1.000 31.116 0 103  LEU A HA   1 c 
ATOM   1305 H HB2  . LEU A 1 88  ? -4.423  -18.840 -9.038  1.000 31.607 0 103  LEU A HB2  1 c 
ATOM   1306 H HB3  . LEU A 1 88  ? -4.188  -18.449 -10.560 1.000 31.624 0 103  LEU A HB3  1 c 
ATOM   1307 H HG   . LEU A 1 88  ? -3.683  -16.699 -8.362  1.000 34.386 0 103  LEU A HG   1 c 
ATOM   1308 H HD11 . LEU A 1 88  ? -2.013  -18.365 -8.533  1.000 37.090 0 103  LEU A HD11 1 c 
ATOM   1309 H HD12 . LEU A 1 88  ? -1.400  -16.945 -8.888  1.000 37.074 0 103  LEU A HD12 1 c 
ATOM   1310 H HD13 . LEU A 1 88  ? -1.759  -17.966 -10.047 1.000 37.090 0 103  LEU A HD13 1 c 
ATOM   1311 H HD21 . LEU A 1 88  ? -4.218  -15.337 -10.106 1.000 34.087 0 103  LEU A HD21 1 c 
ATOM   1312 H HD22 . LEU A 1 88  ? -3.457  -16.248 -11.160 1.000 34.111 0 103  LEU A HD22 1 c 
ATOM   1313 H HD23 . LEU A 1 88  ? -2.632  -15.358 -10.137 1.000 34.156 0 103  LEU A HD23 1 c 
ATOM   1314 N N    . SER A 1 89  ? -7.415  -19.550 -9.910  1.000 31.883 0 104  SER A N    1 ? 
ATOM   1315 C CA   . SER A 1 89  ? -8.175  -20.559 -10.628 1.000 31.599 0 104  SER A CA   1 ? 
ATOM   1316 C C    . SER A 1 89  ? -9.287  -19.923 -11.437 1.000 32.413 0 104  SER A C    1 ? 
ATOM   1317 O O    . SER A 1 89  ? -9.757  -20.530 -12.387 1.000 36.608 0 104  SER A O    1 ? 
ATOM   1318 C CB   . SER A 1 89  ? -8.762  -21.605 -9.685  1.000 34.310 0 104  SER A CB   1 ? 
ATOM   1319 O OG   . SER A 1 89  ? -9.860  -21.078 -8.950  1.000 33.361 0 104  SER A OG   1 ? 
ATOM   1320 H H    . SER A 1 89  ? -7.392  -19.574 -8.997  1.000 32.250 0 104  SER A H    1 c 
ATOM   1321 H HA   . SER A 1 89  ? -7.560  -21.016 -11.256 1.000 32.300 0 104  SER A HA   1 c 
ATOM   1322 H HB2  . SER A 1 89  ? -9.062  -22.371 -10.207 1.000 33.457 0 104  SER A HB2  1 c 
ATOM   1323 H HB3  . SER A 1 89  ? -8.071  -21.907 -9.066  1.000 33.458 0 104  SER A HB3  1 c 
ATOM   1324 H HG   . SER A 1 89  ? -10.151 -21.682 -8.434  0.000 33.440 0 104  SER A HG   1 c 
ATOM   1325 N N    . LEU A 1 90  ? -9.723  -18.715 -11.058 1.000 35.626 0 105  LEU A N    1 ? 
ATOM   1326 C CA   . LEU A 1 90  ? -10.834 -18.081 -11.749 1.000 34.452 0 105  LEU A CA   1 ? 
ATOM   1327 C C    . LEU A 1 90  ? -10.349 -17.443 -13.054 1.000 34.463 0 105  LEU A C    1 ? 
ATOM   1328 O O    . LEU A 1 90  ? -11.183 -17.001 -13.842 1.000 39.391 0 105  LEU A O    1 ? 
ATOM   1329 C CB   . LEU A 1 90  ? -11.512 -17.034 -10.870 1.000 36.812 0 105  LEU A CB   1 ? 
ATOM   1330 C CG   . LEU A 1 90  ? -11.942 -17.491 -9.477  1.000 44.247 0 105  LEU A CG   1 ? 
ATOM   1331 C CD1  . LEU A 1 90  ? -12.477 -16.311 -8.677  1.000 47.568 0 105  LEU A CD1  1 ? 
ATOM   1332 C CD2  . LEU A 1 90  ? -12.972 -18.598 -9.615  1.000 43.051 0 105  LEU A CD2  1 ? 
ATOM   1333 H H    . LEU A 1 90  ? -9.334  -18.283 -10.353 1.000 34.643 0 105  LEU A H    1 c 
ATOM   1334 H HA   . LEU A 1 90  ? -11.496 -18.782 -11.978 1.000 35.175 0 105  LEU A HA   1 c 
ATOM   1335 H HB2  . LEU A 1 90  ? -10.895 -16.273 -10.768 1.000 37.796 0 105  LEU A HB2  1 c 
ATOM   1336 H HB3  . LEU A 1 90  ? -12.309 -16.704 -11.346 1.000 37.811 0 105  LEU A HB3  1 c 
ATOM   1337 H HG   . LEU A 1 90  ? -11.150 -17.855 -9.006  1.000 43.004 0 105  LEU A HG   1 c 
ATOM   1338 H HD11 . LEU A 1 90  ? -11.784 -15.635 -8.591  1.000 46.564 0 105  LEU A HD11 1 c 
ATOM   1339 H HD12 . LEU A 1 90  ? -12.745 -16.613 -7.793  1.000 46.564 0 105  LEU A HD12 1 c 
ATOM   1340 H HD13 . LEU A 1 90  ? -13.246 -15.930 -9.134  1.000 46.564 0 105  LEU A HD13 1 c 
ATOM   1341 H HD21 . LEU A 1 90  ? -12.548 -19.397 -9.970  1.000 43.287 0 105  LEU A HD21 1 c 
ATOM   1342 H HD22 . LEU A 1 90  ? -13.679 -18.312 -10.218 1.000 43.374 0 105  LEU A HD22 1 c 
ATOM   1343 H HD23 . LEU A 1 90  ? -13.353 -18.797 -8.742  1.000 43.374 0 105  LEU A HD23 1 c 
ATOM   1344 N N    . TYR A 1 91  ? -9.019  -17.321 -13.226 1.000 32.086 0 106  TYR A N    1 ? 
ATOM   1345 C CA   . TYR A 1 91  ? -8.397  -16.610 -14.346 1.000 34.492 0 106  TYR A CA   1 ? 
ATOM   1346 C C    . TYR A 1 91  ? -7.382  -17.510 -15.045 1.000 39.199 0 106  TYR A C    1 ? 
ATOM   1347 O O    . TYR A 1 91  ? -6.168  -17.322 -14.908 1.000 44.088 0 106  TYR A O    1 ? 
ATOM   1348 C CB   . TYR A 1 91  ? -7.652  -15.351 -13.864 1.000 28.844 0 106  TYR A CB   1 ? 
ATOM   1349 C CG   . TYR A 1 91  ? -8.503  -14.431 -13.008 1.000 26.731 0 106  TYR A CG   1 ? 
ATOM   1350 C CD1  . TYR A 1 91  ? -9.337  -13.484 -13.591 1.000 26.855 0 106  TYR A CD1  1 ? 
ATOM   1351 C CD2  . TYR A 1 91  ? -8.509  -14.530 -11.624 1.000 24.703 0 106  TYR A CD2  1 ? 
ATOM   1352 C CE1  . TYR A 1 91  ? -10.131 -12.656 -12.817 1.000 28.896 0 106  TYR A CE1  1 ? 
ATOM   1353 C CE2  . TYR A 1 91  ? -9.311  -13.721 -10.851 1.000 26.418 0 106  TYR A CE2  1 ? 
ATOM   1354 C CZ   . TYR A 1 91  ? -10.113 -12.773 -11.444 1.000 25.160 0 106  TYR A CZ   1 ? 
ATOM   1355 O OH   . TYR A 1 91  ? -10.945 -12.019 -10.710 1.000 29.402 0 106  TYR A OH   1 ? 
ATOM   1356 H H    . TYR A 1 91  ? -8.465  -17.696 -12.605 1.000 33.202 0 106  TYR A H    1 c 
ATOM   1357 H HA   . TYR A 1 91  ? -9.098  -16.340 -14.994 1.000 33.938 0 106  TYR A HA   1 c 
ATOM   1358 H HB2  . TYR A 1 91  ? -6.867  -15.630 -13.342 1.000 29.619 0 106  TYR A HB2  1 c 
ATOM   1359 H HB3  . TYR A 1 91  ? -7.335  -14.854 -14.650 1.000 29.449 0 106  TYR A HB3  1 c 
ATOM   1360 H HD1  . TYR A 1 91  ? -9.354  -13.395 -14.530 1.000 27.273 0 106  TYR A HD1  1 c 
ATOM   1361 H HD2  . TYR A 1 91  ? -7.963  -15.176 -11.204 1.000 25.630 0 106  TYR A HD2  1 c 
ATOM   1362 H HE1  . TYR A 1 91  ? -10.699 -12.027 -13.228 1.000 27.567 0 106  TYR A HE1  1 c 
ATOM   1363 H HE2  . TYR A 1 91  ? -9.306  -13.810 -9.914  1.000 25.769 0 106  TYR A HE2  1 c 
ATOM   1364 H HH   . TYR A 1 91  ? -11.686 -12.433 -10.596 0.000 29.310 0 106  TYR A HH   1 c 
ATOM   1365 N N    . PRO A 1 92  ? -7.824  -18.505 -15.842 1.000 49.894 0 107  PRO A N    1 ? 
ATOM   1366 C CA   . PRO A 1 92  ? -6.888  -19.474 -16.423 1.000 51.017 0 107  PRO A CA   1 ? 
ATOM   1367 C C    . PRO A 1 92  ? -5.825  -18.764 -17.258 1.000 47.929 0 107  PRO A C    1 ? 
ATOM   1368 O O    . PRO A 1 92  ? -6.165  -17.847 -18.008 1.000 44.192 0 107  PRO A O    1 ? 
ATOM   1369 C CB   . PRO A 1 92  ? -7.789  -20.391 -17.267 1.000 55.211 0 107  PRO A CB   1 ? 
ATOM   1370 C CG   . PRO A 1 92  ? -9.041  -19.574 -17.505 1.000 59.289 0 107  PRO A CG   1 ? 
ATOM   1371 C CD   . PRO A 1 92  ? -9.221  -18.724 -16.251 1.000 53.613 0 107  PRO A CD   1 ? 
ATOM   1372 H HA   . PRO A 1 92  ? -6.463  -19.996 -15.698 1.000 50.930 0 107  PRO A HA   1 c 
ATOM   1373 H HB2  . PRO A 1 92  ? -7.354  -20.624 -18.120 1.000 55.091 0 107  PRO A HB2  1 c 
ATOM   1374 H HB3  . PRO A 1 92  ? -8.000  -21.222 -16.779 1.000 55.126 0 107  PRO A HB3  1 c 
ATOM   1375 H HG2  . PRO A 1 92  ? -8.939  -19.005 -18.296 1.000 56.957 0 107  PRO A HG2  1 c 
ATOM   1376 H HG3  . PRO A 1 92  ? -9.816  -20.159 -17.639 1.000 57.019 0 107  PRO A HG3  1 c 
ATOM   1377 H HD2  . PRO A 1 92  ? -9.673  -17.877 -16.460 1.000 53.606 0 107  PRO A HD2  1 c 
ATOM   1378 H HD3  . PRO A 1 92  ? -9.726  -19.208 -15.561 1.000 53.856 0 107  PRO A HD3  1 c 
ATOM   1379 N N    . ARG A 1 93  ? -4.556  -19.200 -17.126 1.000 47.542 0 108  ARG A N    1 ? 
ATOM   1380 C CA   . ARG A 1 93  ? -3.461  -18.630 -17.898 1.000 50.727 0 108  ARG A CA   1 ? 
ATOM   1381 C C    . ARG A 1 93  ? -3.148  -19.537 -19.091 1.000 53.964 0 108  ARG A C    1 ? 
ATOM   1382 O O    . ARG A 1 93  ? -2.594  -20.614 -18.919 1.000 58.826 0 108  ARG A O    1 ? 
ATOM   1383 C CB   . ARG A 1 93  ? -2.231  -18.385 -17.011 1.000 51.186 0 108  ARG A CB   1 ? 
ATOM   1384 C CG   . ARG A 1 93  ? -2.476  -17.345 -15.925 1.000 49.598 0 108  ARG A CG   1 ? 
ATOM   1385 C CD   . ARG A 1 93  ? -1.233  -16.969 -15.157 1.000 46.645 0 108  ARG A CD   1 ? 
ATOM   1386 N NE   . ARG A 1 93  ? -0.237  -16.098 -15.814 1.000 43.187 0 108  ARG A NE   1 ? 
ATOM   1387 C CZ   . ARG A 1 93  ? 1.044   -16.459 -15.964 1.000 41.481 0 108  ARG A CZ   1 ? 
ATOM   1388 N NH1  . ARG A 1 93  ? 1.964   -15.602 -16.330 1.000 34.296 0 108  ARG A NH1  1 ? 
ATOM   1389 N NH2  . ARG A 1 93  ? 1.441   -17.698 -15.665 1.000 45.440 0 108  ARG A NH2  1 ? 
ATOM   1390 H H    . ARG A 1 93  ? -4.373  -19.874 -16.537 1.000 48.374 0 108  ARG A H    1 c 
ATOM   1391 H HA   . ARG A 1 93  ? -3.754  -17.752 -18.245 1.000 50.690 0 108  ARG A HA   1 c 
ATOM   1392 H HB2  . ARG A 1 93  ? -1.969  -19.231 -16.588 1.000 50.716 0 108  ARG A HB2  1 c 
ATOM   1393 H HB3  . ARG A 1 93  ? -1.485  -18.088 -17.574 1.000 50.716 0 108  ARG A HB3  1 c 
ATOM   1394 H HG2  . ARG A 1 93  ? -2.849  -16.536 -16.337 1.000 49.139 0 108  ARG A HG2  1 c 
ATOM   1395 H HG3  . ARG A 1 93  ? -3.144  -17.691 -15.295 1.000 49.230 0 108  ARG A HG3  1 c 
ATOM   1396 H HD2  . ARG A 1 93  ? -1.533  -16.532 -14.336 1.000 46.009 0 108  ARG A HD2  1 c 
ATOM   1397 H HD3  . ARG A 1 93  ? -0.796  -17.802 -14.889 1.000 46.332 0 108  ARG A HD3  1 c 
ATOM   1398 H HE   . ARG A 1 93  ? -0.493  -15.322 -16.116 1.000 43.399 0 108  ARG A HE   1 c 
ATOM   1399 H HH11 . ARG A 1 93  ? 2.764   -15.892 -16.575 1.000 36.453 0 108  ARG A HH11 1 c 
ATOM   1400 H HH12 . ARG A 1 93  ? 1.783   -14.737 -16.330 1.000 36.480 0 108  ARG A HH12 1 c 
ATOM   1401 H HH21 . ARG A 1 93  ? 2.024   -17.826 -15.013 1.000 44.190 0 108  ARG A HH21 1 c 
ATOM   1402 H HH22 . ARG A 1 93  ? 1.120   -18.384 -16.122 1.000 44.213 0 108  ARG A HH22 1 c 
ATOM   1403 N N    . GLU A 1 94  ? -3.524  -19.102 -20.300 1.000 61.087 0 109  GLU A N    1 ? 
ATOM   1404 C CA   . GLU A 1 94  ? -3.136  -19.789 -21.523 1.000 65.483 0 109  GLU A CA   1 ? 
ATOM   1405 C C    . GLU A 1 94  ? -1.865  -19.140 -22.065 1.000 66.704 0 109  GLU A C    1 ? 
ATOM   1406 O O    . GLU A 1 94  ? -1.916  -17.998 -22.519 1.000 67.558 0 109  GLU A O    1 ? 
ATOM   1407 C CB   . GLU A 1 94  ? -4.252  -19.721 -22.566 1.000 72.233 0 109  GLU A CB   1 ? 
ATOM   1408 H H    . GLU A 1 94  ? -4.044  -18.352 -20.364 1.000 60.082 0 109  GLU A H    1 c 
ATOM   1409 H HA   . GLU A 1 94  ? -2.951  -20.739 -21.311 1.000 65.771 0 109  GLU A HA   1 c 
ATOM   1410 H HB2  . GLU A 1 94  ? -4.514  -18.784 -22.685 1.000 70.155 0 109  GLU A HB2  1 c 
ATOM   1411 H HB3  . GLU A 1 94  ? -3.969  -20.169 -23.371 0.000 72.590 0 109  GLU A HB3  1 c 
ATOM   1412 N N    . GLY A 1 95  ? -0.733  -19.853 -21.952 1.000 57.209 0 110  GLY A N    1 ? 
ATOM   1413 C CA   . GLY A 1 95  ? 0.487   -19.527 -22.682 1.000 57.727 0 110  GLY A CA   1 ? 
ATOM   1414 C C    . GLY A 1 95  ? 1.621   -19.024 -21.783 1.000 55.084 0 110  GLY A C    1 ? 
ATOM   1415 O O    . GLY A 1 95  ? 2.575   -18.418 -22.265 1.000 45.662 0 110  GLY A O    1 ? 
ATOM   1416 H H    . GLY A 1 95  ? -0.727  -20.582 -21.400 1.000 59.505 0 110  GLY A H    1 c 
ATOM   1417 H HA2  . GLY A 1 95  ? 0.790   -20.334 -23.162 1.000 57.026 0 110  GLY A HA2  1 c 
ATOM   1418 H HA3  . GLY A 1 95  ? 0.282   -18.840 -23.358 1.000 57.114 0 110  GLY A HA3  1 c 
ATOM   1419 N N    . GLY A 1 96  ? 1.527   -19.282 -20.472 1.000 53.615 0 111  GLY A N    1 ? 
ATOM   1420 C CA   . GLY A 1 96  ? 2.403   -18.636 -19.507 1.000 54.609 0 111  GLY A CA   1 ? 
ATOM   1421 C C    . GLY A 1 96  ? 2.185   -17.121 -19.442 1.000 44.238 0 111  GLY A C    1 ? 
ATOM   1422 O O    . GLY A 1 96  ? 3.092   -16.389 -19.015 1.000 48.850 0 111  GLY A O    1 ? 
ATOM   1423 H H    . GLY A 1 96  ? 0.910   -19.884 -20.170 1.000 54.275 0 111  GLY A H    1 c 
ATOM   1424 H HA2  . GLY A 1 96  ? 2.241   -19.027 -18.616 1.000 51.873 0 111  GLY A HA2  1 c 
ATOM   1425 H HA3  . GLY A 1 96  ? 3.341   -18.821 -19.751 1.000 51.845 0 111  GLY A HA3  1 c 
ATOM   1426 N N    . VAL A 1 97  ? 0.978   -16.658 -19.839 1.000 37.120 0 112  VAL A N    1 ? 
ATOM   1427 C CA   . VAL A 1 97  ? 0.701   -15.227 -19.826 1.000 30.735 0 112  VAL A CA   1 ? 
ATOM   1428 C C    . VAL A 1 97  ? -0.661  -14.911 -19.217 1.000 27.558 0 112  VAL A C    1 ? 
ATOM   1429 O O    . VAL A 1 97  ? -1.625  -15.666 -19.246 1.000 28.332 0 112  VAL A O    1 ? 
ATOM   1430 C CB   . VAL A 1 97  ? 0.865   -14.541 -21.194 1.000 34.697 0 112  VAL A CB   1 ? 
ATOM   1431 C CG1  . VAL A 1 97  ? 2.289   -14.692 -21.725 1.000 39.530 0 112  VAL A CG1  1 ? 
ATOM   1432 C CG2  . VAL A 1 97  ? -0.184  -15.001 -22.191 1.000 33.816 0 112  VAL A CG2  1 ? 
ATOM   1433 H H    . VAL A 1 97  ? 0.323   -17.238 -20.103 1.000 37.385 0 112  VAL A H    1 c 
ATOM   1434 H HA   . VAL A 1 97  ? 1.366   -14.823 -19.235 1.000 31.869 0 112  VAL A HA   1 c 
ATOM   1435 H HB   . VAL A 1 97  ? 0.717   -13.579 -21.045 1.000 34.435 0 112  VAL A HB   1 c 
ATOM   1436 H HG11 . VAL A 1 97  ? 2.472   -15.630 -21.902 1.000 38.064 0 112  VAL A HG11 1 c 
ATOM   1437 H HG12 . VAL A 1 97  ? 2.920   -14.359 -21.064 1.000 38.048 0 112  VAL A HG12 1 c 
ATOM   1438 H HG13 . VAL A 1 97  ? 2.385   -14.183 -22.547 1.000 38.047 0 112  VAL A HG13 1 c 
ATOM   1439 H HG21 . VAL A 1 97  ? 0.034   -14.656 -23.074 1.000 34.098 0 112  VAL A HG21 1 c 
ATOM   1440 H HG22 . VAL A 1 97  ? -1.058  -14.669 -21.923 1.000 34.069 0 112  VAL A HG22 1 c 
ATOM   1441 H HG23 . VAL A 1 97  ? -0.202  -15.972 -22.220 1.000 34.202 0 112  VAL A HG23 1 c 
ATOM   1442 N N    . SER A 1 98  ? -0.722  -13.699 -18.647 1.000 20.446 0 113  SER A N    1 ? 
ATOM   1443 C CA   . SER A 1 98  ? -1.797  -13.237 -17.823 1.000 19.770 0 113  SER A CA   1 ? 
ATOM   1444 C C    . SER A 1 98  ? -2.863  -12.604 -18.703 1.000 20.046 0 113  SER A C    1 ? 
ATOM   1445 O O    . SER A 1 98  ? -2.570  -12.160 -19.795 1.000 23.390 0 113  SER A O    1 ? 
ATOM   1446 C CB   . SER A 1 98  ? -1.279  -12.191 -16.845 1.000 20.602 0 113  SER A CB   1 ? 
ATOM   1447 O OG   . SER A 1 98  ? -0.251  -12.733 -16.030 1.000 21.159 0 113  SER A OG   1 ? 
ATOM   1448 H H    . SER A 1 98  ? -0.036  -13.119 -18.810 1.000 21.896 0 113  SER A H    1 c 
ATOM   1449 H HA   . SER A 1 98  ? -2.186  -14.000 -17.323 1.000 20.169 0 113  SER A HA   1 c 
ATOM   1450 H HB2  . SER A 1 98  ? -0.931  -11.426 -17.343 1.000 20.540 0 113  SER A HB2  1 c 
ATOM   1451 H HB3  . SER A 1 98  ? -2.013  -11.882 -16.281 1.000 20.542 0 113  SER A HB3  1 c 
ATOM   1452 H HG   . SER A 1 98  ? 0.014   -12.129 -15.499 0.000 21.150 0 113  SER A HG   1 c 
ATOM   1453 N N    . SER A 1 99  ? -4.056  -12.480 -18.159 1.000 20.247 0 114  SER A N    1 ? 
ATOM   1454 C CA   . SER A 1 99  ? -5.179  -11.862 -18.824 1.000 18.275 0 114  SER A CA   1 ? 
ATOM   1455 C C    . SER A 1 99  ? -5.415  -10.458 -18.291 1.000 17.643 0 114  SER A C    1 ? 
ATOM   1456 O O    . SER A 1 99  ? -5.043  -10.129 -17.152 1.000 19.470 0 114  SER A O    1 ? 
ATOM   1457 C CB   . SER A 1 99  ? -6.438  -12.690 -18.643 1.000 21.608 0 114  SER A CB   1 ? 
ATOM   1458 O OG   . SER A 1 99  ? -6.857  -12.750 -17.283 1.000 21.974 0 114  SER A OG   1 ? 
ATOM   1459 H H    . SER A 1 99  ? -4.183  -12.803 -17.313 1.000 19.736 0 114  SER A H    1 c 
ATOM   1460 H HA   . SER A 1 99  ? -4.977  -11.800 -19.789 1.000 19.121 0 114  SER A HA   1 c 
ATOM   1461 H HB2  . SER A 1 99  ? -7.153  -12.304 -19.183 1.000 20.894 0 114  SER A HB2  1 c 
ATOM   1462 H HB3  . SER A 1 99  ? -6.274  -13.595 -18.968 1.000 20.890 0 114  SER A HB3  1 c 
ATOM   1463 H HG   . SER A 1 99  ? -7.561  -13.220 -17.238 0.000 21.950 0 114  SER A HG   1 c 
ATOM   1464 N N    . ARG A 1 100 ? -6.136  -9.635  -19.066 1.000 17.447 0 115  ARG A N    1 ? 
ATOM   1465 C CA   . ARG A 1 100 ? -6.485  -8.310  -18.595 1.000 17.856 0 115  ARG A CA   1 ? 
ATOM   1466 C C    . ARG A 1 100 ? -7.353  -8.383  -17.343 1.000 17.772 0 115  ARG A C    1 ? 
ATOM   1467 O O    . ARG A 1 100 ? -7.185  -7.549  -16.454 1.000 18.938 0 115  ARG A O    1 ? 
ATOM   1468 C CB   . ARG A 1 100 ? -7.133  -7.519  -19.738 1.000 17.805 0 115  ARG A CB   1 ? 
ATOM   1469 C CG   . ARG A 1 100 ? -7.514  -6.087  -19.396 1.000 18.426 0 115  ARG A CG   1 ? 
ATOM   1470 C CD   . ARG A 1 100 ? -7.981  -5.323  -20.649 1.000 17.512 0 115  ARG A CD   1 ? 
ATOM   1471 N NE   . ARG A 1 100 ? -6.886  -5.215  -21.609 1.000 17.259 0 115  ARG A NE   1 ? 
ATOM   1472 C CZ   . ARG A 1 100 ? -5.933  -4.320  -21.605 1.000 17.769 0 115  ARG A CZ   1 ? 
ATOM   1473 N NH1  . ARG A 1 100 ? -6.031  -3.283  -20.761 1.000 17.126 0 115  ARG A NH1  1 ? 
ATOM   1474 N NH2  . ARG A 1 100 ? -4.925  -4.448  -22.440 1.000 18.084 0 115  ARG A NH2  1 ? 
ATOM   1475 H H    . ARG A 1 100 ? -6.414  -9.906  -19.894 1.000 17.602 0 115  ARG A H    1 c 
ATOM   1476 H HA   . ARG A 1 100 ? -5.643  -7.845  -18.354 1.000 17.765 0 115  ARG A HA   1 c 
ATOM   1477 H HB2  . ARG A 1 100 ? -6.511  -7.506  -20.495 1.000 17.953 0 115  ARG A HB2  1 c 
ATOM   1478 H HB3  . ARG A 1 100 ? -7.940  -7.996  -20.027 1.000 17.956 0 115  ARG A HB3  1 c 
ATOM   1479 H HG2  . ARG A 1 100 ? -8.238  -6.090  -18.733 1.000 18.073 0 115  ARG A HG2  1 c 
ATOM   1480 H HG3  . ARG A 1 100 ? -6.739  -5.627  -19.007 1.000 18.074 0 115  ARG A HG3  1 c 
ATOM   1481 H HD2  . ARG A 1 100 ? -8.728  -5.802  -21.063 1.000 17.656 0 115  ARG A HD2  1 c 
ATOM   1482 H HD3  . ARG A 1 100 ? -8.294  -4.429  -20.402 1.000 17.682 0 115  ARG A HD3  1 c 
ATOM   1483 H HE   . ARG A 1 100 ? -6.867  -5.805  -22.250 1.000 17.447 0 115  ARG A HE   1 c 
ATOM   1484 H HH11 . ARG A 1 100 ? -5.640  -2.512  -20.979 1.000 17.327 0 115  ARG A HH11 1 c 
ATOM   1485 H HH12 . ARG A 1 100 ? -6.470  -3.365  -19.991 1.000 17.327 0 115  ARG A HH12 1 c 
ATOM   1486 H HH21 . ARG A 1 100 ? -4.247  -3.883  -22.393 1.000 17.973 0 115  ARG A HH21 1 c 
ATOM   1487 H HH22 . ARG A 1 100 ? -4.925  -5.093  -23.044 1.000 17.974 0 115  ARG A HH22 1 c 
ATOM   1488 N N    . GLU A 1 101 ? -8.272  -9.362  -17.251 1.000 17.600 0 116  GLU A N    1 ? 
ATOM   1489 C CA   . GLU A 1 101 ? -9.112  -9.494  -16.076 1.000 20.165 0 116  GLU A CA   1 ? 
ATOM   1490 C C    . GLU A 1 101 ? -8.283  -9.786  -14.829 1.000 17.866 0 116  GLU A C    1 ? 
ATOM   1491 O O    . GLU A 1 101 ? -8.625  -9.255  -13.767 1.000 19.606 0 116  GLU A O    1 ? 
ATOM   1492 C CB   . GLU A 1 101 ? -10.168 -10.577 -16.206 1.000 21.344 0 116  GLU A CB   1 ? 
ATOM   1493 C CG   . GLU A 1 101 ? -11.137 -10.352 -17.353 1.000 24.627 0 116  GLU A CG   1 ? 
ATOM   1494 C CD   . GLU A 1 101 ? -10.676 -10.806 -18.738 1.000 27.381 0 116  GLU A CD   1 ? 
ATOM   1495 O OE1  . GLU A 1 101 ? -9.544  -11.285 -18.920 1.000 21.915 0 116  GLU A OE1  1 ? 
ATOM   1496 O OE2  . GLU A 1 101 ? -11.529 -10.686 -19.657 1.000 29.794 0 116  GLU A OE2  1 ? 
ATOM   1497 H H    . GLU A 1 101 ? -8.365  -9.962  -17.934 1.000 18.280 0 116  GLU A H    1 c 
ATOM   1498 H HA   . GLU A 1 101 ? -9.580  -8.631  -15.939 1.000 19.401 0 116  GLU A HA   1 c 
ATOM   1499 H HB2  . GLU A 1 101 ? -9.721  -11.440 -16.328 1.000 21.764 0 116  GLU A HB2  1 c 
ATOM   1500 H HB3  . GLU A 1 101 ? -10.678 -10.621 -15.370 1.000 21.747 0 116  GLU A HB3  1 c 
ATOM   1501 H HG2  . GLU A 1 101 ? -11.973 -10.819 -17.146 1.000 24.416 0 116  GLU A HG2  1 c 
ATOM   1502 H HG3  . GLU A 1 101 ? -11.348 -9.395  -17.401 1.000 24.417 0 116  GLU A HG3  1 c 
ATOM   1503 N N    . LEU A 1 102 ? -7.250  -10.606 -14.949 1.000 19.773 0 117  LEU A N    1 ? 
ATOM   1504 C CA   . LEU A 1 102 ? -6.411  -10.945 -13.811 1.000 19.375 0 117  LEU A CA   1 ? 
ATOM   1505 C C    . LEU A 1 102 ? -5.649  -9.715  -13.329 1.000 18.525 0 117  LEU A C    1 ? 
ATOM   1506 O O    . LEU A 1 102 ? -5.593  -9.405  -12.113 1.000 18.982 0 117  LEU A O    1 ? 
ATOM   1507 C CB   . LEU A 1 102 ? -5.487  -12.097 -14.173 1.000 18.373 0 117  LEU A CB   1 ? 
ATOM   1508 C CG   . LEU A 1 102 ? -4.473  -12.474 -13.095 1.000 18.932 0 117  LEU A CG   1 ? 
ATOM   1509 C CD1  . LEU A 1 102 ? -5.160  -12.760 -11.737 1.000 20.675 0 117  LEU A CD1  1 ? 
ATOM   1510 C CD2  . LEU A 1 102 ? -3.734  -13.690 -13.563 1.000 20.219 0 117  LEU A CD2  1 ? 
ATOM   1511 H H    . LEU A 1 102 ? -7.059  -10.974 -15.763 1.000 19.198 0 117  LEU A H    1 c 
ATOM   1512 H HA   . LEU A 1 102 ? -7.008  -11.238 -13.076 1.000 19.115 0 117  LEU A HA   1 c 
ATOM   1513 H HB2  . LEU A 1 102 ? -6.042  -12.886 -14.372 1.000 18.798 0 117  LEU A HB2  1 c 
ATOM   1514 H HB3  . LEU A 1 102 ? -4.997  -11.854 -14.992 1.000 18.742 0 117  LEU A HB3  1 c 
ATOM   1515 H HG   . LEU A 1 102 ? -3.828  -11.729 -12.983 1.000 19.365 0 117  LEU A HG   1 c 
ATOM   1516 H HD11 . LEU A 1 102 ? -5.519  -11.935 -11.372 1.000 20.140 0 117  LEU A HD11 1 c 
ATOM   1517 H HD12 . LEU A 1 102 ? -4.510  -13.131 -11.117 1.000 20.154 0 117  LEU A HD12 1 c 
ATOM   1518 H HD13 . LEU A 1 102 ? -5.882  -13.397 -11.866 1.000 20.168 0 117  LEU A HD13 1 c 
ATOM   1519 H HD21 . LEU A 1 102 ? -3.244  -13.479 -14.376 1.000 19.831 0 117  LEU A HD21 1 c 
ATOM   1520 H HD22 . LEU A 1 102 ? -4.366  -14.406 -13.744 1.000 19.825 0 117  LEU A HD22 1 c 
ATOM   1521 H HD23 . LEU A 1 102 ? -3.110  -13.976 -12.875 1.000 19.856 0 117  LEU A HD23 1 c 
ATOM   1522 N N    . VAL A 1 103 ? -5.068  -8.975  -14.289 1.000 17.580 0 118  VAL A N    1 ? 
ATOM   1523 C CA   . VAL A 1 103 ? -4.329  -7.759  -13.953 1.000 18.618 0 118  VAL A CA   1 ? 
ATOM   1524 C C    . VAL A 1 103 ? -5.251  -6.762  -13.263 1.000 15.995 0 118  VAL A C    1 ? 
ATOM   1525 O O    . VAL A 1 103 ? -4.862  -6.156  -12.246 1.000 17.537 0 118  VAL A O    1 ? 
ATOM   1526 C CB   . VAL A 1 103 ? -3.622  -7.127  -15.176 1.000 17.562 0 118  VAL A CB   1 ? 
ATOM   1527 C CG1  . VAL A 1 103 ? -3.015  -5.770  -14.840 1.000 18.334 0 118  VAL A CG1  1 ? 
ATOM   1528 C CG2  . VAL A 1 103 ? -2.557  -8.083  -15.700 1.000 17.817 0 118  VAL A CG2  1 ? 
ATOM   1529 H H    . VAL A 1 103 ? -5.130  -9.230  -15.165 1.000 18.044 0 118  VAL A H    1 c 
ATOM   1530 H HA   . VAL A 1 103 ? -3.636  -8.010  -13.312 1.000 17.717 0 118  VAL A HA   1 c 
ATOM   1531 H HB   . VAL A 1 103 ? -4.302  -7.000  -15.879 1.000 17.943 0 118  VAL A HB   1 c 
ATOM   1532 H HG11 . VAL A 1 103 ? -2.478  -5.844  -14.034 1.000 18.106 0 118  VAL A HG11 1 c 
ATOM   1533 H HG12 . VAL A 1 103 ? -3.723  -5.120  -14.699 1.000 18.096 0 118  VAL A HG12 1 c 
ATOM   1534 H HG13 . VAL A 1 103 ? -2.452  -5.478  -15.577 1.000 18.124 0 118  VAL A HG13 1 c 
ATOM   1535 H HG21 . VAL A 1 103 ? -2.093  -7.673  -16.450 1.000 17.746 0 118  VAL A HG21 1 c 
ATOM   1536 H HG22 . VAL A 1 103 ? -2.976  -8.909  -15.994 1.000 17.752 0 118  VAL A HG22 1 c 
ATOM   1537 H HG23 . VAL A 1 103 ? -1.919  -8.278  -14.994 1.000 17.744 0 118  VAL A HG23 1 c 
ATOM   1538 N N    . LYS A 1 104 ? -6.486  -6.592  -13.790 1.000 17.921 0 119  LYS A N    1 ? 
ATOM   1539 C CA   . LYS A 1 104 ? -7.472  -5.702  -13.165 1.000 18.775 0 119  LYS A CA   1 ? 
ATOM   1540 C C    . LYS A 1 104 ? -7.827  -6.120  -11.743 1.000 18.721 0 119  LYS A C    1 ? 
ATOM   1541 O O    . LYS A 1 104 ? -8.010  -5.240  -10.894 1.000 19.785 0 119  LYS A O    1 ? 
ATOM   1542 C CB   . LYS A 1 104 ? -8.739  -5.507  -14.018 1.000 21.655 0 119  LYS A CB   1 ? 
ATOM   1543 C CG   . LYS A 1 104 ? -9.742  -4.494  -13.497 1.000 28.097 0 119  LYS A CG   1 ? 
ATOM   1544 C CD   . LYS A 1 104 ? -9.240  -3.077  -13.192 1.000 36.282 0 119  LYS A CD   1 ? 
ATOM   1545 C CE   . LYS A 1 104 ? -10.333 -2.026  -13.221 1.000 42.384 0 119  LYS A CE   1 ? 
ATOM   1546 N NZ   . LYS A 1 104 ? -11.472 -2.351  -12.346 1.000 43.003 0 119  LYS A NZ   1 ? 
ATOM   1547 H H    . LYS A 1 104 ? -6.715  -7.036  -14.555 1.000 17.651 0 119  LYS A H    1 c 
ATOM   1548 H HA   . LYS A 1 104 ? -7.050  -4.810  -13.101 1.000 19.224 0 119  LYS A HA   1 c 
ATOM   1549 H HB2  . LYS A 1 104 ? -8.467  -5.232  -14.919 1.000 22.273 0 119  LYS A HB2  1 c 
ATOM   1550 H HB3  . LYS A 1 104 ? -9.193  -6.373  -14.099 1.000 22.273 0 119  LYS A HB3  1 c 
ATOM   1551 H HG2  . LYS A 1 104 ? -10.466 -4.426  -14.157 1.000 28.088 0 119  LYS A HG2  1 c 
ATOM   1552 H HG3  . LYS A 1 104 ? -10.141 -4.860  -12.678 1.000 27.992 0 119  LYS A HG3  1 c 
ATOM   1553 H HD2  . LYS A 1 104 ? -8.819  -3.073  -12.305 1.000 35.370 0 119  LYS A HD2  1 c 
ATOM   1554 H HD3  . LYS A 1 104 ? -8.553  -2.837  -13.851 1.000 35.457 0 119  LYS A HD3  1 c 
ATOM   1555 H HE2  . LYS A 1 104 ? -9.959  -1.172  -12.941 1.000 41.063 0 119  LYS A HE2  1 c 
ATOM   1556 H HE3  . LYS A 1 104 ? -10.657 -1.923  -14.133 1.000 41.102 0 119  LYS A HE3  1 c 
ATOM   1557 H HZ1  . LYS A 1 104 ? -11.173 -2.542  -11.514 1.000 42.658 0 119  LYS A HZ1  1 c 
ATOM   1558 H HZ2  . LYS A 1 104 ? -11.923 -3.065  -12.673 1.000 42.685 0 119  LYS A HZ2  1 c 
ATOM   1559 H HZ3  . LYS A 1 104 ? -12.034 -1.642  -12.302 1.000 42.758 0 119  LYS A HZ3  1 c 
ATOM   1560 N N    . LYS A 1 105 ? -7.953  -7.427  -11.497 1.000 18.115 0 120  LYS A N    1 ? 
ATOM   1561 C CA   . LYS A 1 105 ? -8.304  -7.943  -10.190 1.000 20.008 0 120  LYS A CA   1 ? 
ATOM   1562 C C    . LYS A 1 105 ? -7.195  -7.594  -9.211  1.000 18.428 0 120  LYS A C    1 ? 
ATOM   1563 O O    . LYS A 1 105 ? -7.462  -7.131  -8.110  1.000 19.302 0 120  LYS A O    1 ? 
ATOM   1564 C CB   . LYS A 1 105 ? -8.537  -9.450  -10.234 1.000 21.344 0 120  LYS A CB   1 ? 
ATOM   1565 C CG   . LYS A 1 105 ? -8.851  -10.041 -8.843  1.000 22.115 0 120  LYS A CG   1 ? 
ATOM   1566 C CD   . LYS A 1 105 ? -10.171 -9.545  -8.270  1.000 24.928 0 120  LYS A CD   1 ? 
ATOM   1567 C CE   . LYS A 1 105 ? -10.399 -10.192 -6.933  1.000 29.518 0 120  LYS A CE   1 ? 
ATOM   1568 N NZ   . LYS A 1 105 ? -11.502 -9.527  -6.226  1.000 36.291 0 120  LYS A NZ   1 ? 
ATOM   1569 H H    . LYS A 1 105 ? -7.817  -8.022  -12.178 1.000 18.686 0 120  LYS A H    1 c 
ATOM   1570 H HA   . LYS A 1 105 ? -9.138  -7.496  -9.896  1.000 19.615 0 120  LYS A HA   1 c 
ATOM   1571 H HB2  . LYS A 1 105 ? -9.286  -9.644  -10.837 1.000 21.199 0 120  LYS A HB2  1 c 
ATOM   1572 H HB3  . LYS A 1 105 ? -7.737  -9.890  -10.592 1.000 21.189 0 120  LYS A HB3  1 c 
ATOM   1573 H HG2  . LYS A 1 105 ? -8.882  -11.020 -8.918  1.000 22.551 0 120  LYS A HG2  1 c 
ATOM   1574 H HG3  . LYS A 1 105 ? -8.124  -9.809  -8.226  1.000 22.564 0 120  LYS A HG3  1 c 
ATOM   1575 H HD2  . LYS A 1 105 ? -10.143 -8.570  -8.160  1.000 25.206 0 120  LYS A HD2  1 c 
ATOM   1576 H HD3  . LYS A 1 105 ? -10.906 -9.779  -8.878  1.000 25.223 0 120  LYS A HD3  1 c 
ATOM   1577 H HE2  . LYS A 1 105 ? -10.619 -11.133 -7.056  1.000 29.845 0 120  LYS A HE2  1 c 
ATOM   1578 H HE3  . LYS A 1 105 ? -9.591  -10.133 -6.393  1.000 29.717 0 120  LYS A HE3  1 c 
ATOM   1579 H HZ1  . LYS A 1 105 ? -12.255 -9.563  -6.730  1.000 33.975 0 120  LYS A HZ1  1 c 
ATOM   1580 H HZ2  . LYS A 1 105 ? -11.289 -8.661  -6.071  1.000 33.968 0 120  LYS A HZ2  1 c 
ATOM   1581 H HZ3  . LYS A 1 105 ? -11.653 -9.943  -5.435  1.000 34.022 0 120  LYS A HZ3  1 c 
ATOM   1582 N N    . VAL A 1 106 ? -5.929  -7.753  -9.636  1.000 19.951 0 121  VAL A N    1 ? 
ATOM   1583 C CA   . VAL A 1 106 ? -4.810  -7.470  -8.742  1.000 20.077 0 121  VAL A CA   1 ? 
ATOM   1584 C C    . VAL A 1 106 ? -4.815  -5.974  -8.436  1.000 20.159 0 121  VAL A C    1 ? 
ATOM   1585 O O    . VAL A 1 106 ? -4.636  -5.556  -7.284  1.000 17.123 0 121  VAL A O    1 ? 
ATOM   1586 C CB   . VAL A 1 106 ? -3.449  -7.947  -9.283  1.000 18.780 0 121  VAL A CB   1 ? 
ATOM   1587 C CG1  . VAL A 1 106 ? -2.299  -7.514  -8.372  1.000 19.772 0 121  VAL A CG1  1 ? 
ATOM   1588 C CG2  . VAL A 1 106 ? -3.408  -9.462  -9.515  1.000 20.777 0 121  VAL A CG2  1 ? 
ATOM   1589 H H    . VAL A 1 106 ? -5.760  -8.045  -10.485 1.000 19.600 0 121  VAL A H    1 c 
ATOM   1590 H HA   . VAL A 1 106 ? -4.975  -7.946  -7.904  1.000 19.813 0 121  VAL A HA   1 c 
ATOM   1591 H HB   . VAL A 1 106 ? -3.317  -7.508  -10.157 1.000 19.562 0 121  VAL A HB   1 c 
ATOM   1592 H HG11 . VAL A 1 106 ? -2.519  -7.725  -7.449  1.000 19.479 0 121  VAL A HG11 1 c 
ATOM   1593 H HG12 . VAL A 1 106 ? -2.154  -6.557  -8.459  1.000 19.482 0 121  VAL A HG12 1 c 
ATOM   1594 H HG13 . VAL A 1 106 ? -1.488  -7.986  -8.627  1.000 19.488 0 121  VAL A HG13 1 c 
ATOM   1595 H HG21 . VAL A 1 106 ? -2.548  -9.709  -9.896  1.000 20.170 0 121  VAL A HG21 1 c 
ATOM   1596 H HG22 . VAL A 1 106 ? -4.117  -9.717  -10.127 1.000 20.164 0 121  VAL A HG22 1 c 
ATOM   1597 H HG23 . VAL A 1 106 ? -3.530  -9.923  -8.668  1.000 20.195 0 121  VAL A HG23 1 c 
ATOM   1598 N N    . SER A 1 107 ? -5.014  -5.122  -9.455  1.000 19.063 0 122  SER A N    1 ? 
ATOM   1599 C CA   . SER A 1 107 ? -5.100  -3.702  -9.228  1.000 19.427 0 122  SER A CA   1 ? 
ATOM   1600 C C    . SER A 1 107 ? -6.220  -3.339  -8.238  1.000 19.433 0 122  SER A C    1 ? 
ATOM   1601 O O    . SER A 1 107 ? -6.031  -2.482  -7.377  1.000 17.799 0 122  SER A O    1 ? 
ATOM   1602 C CB   . SER A 1 107 ? -5.290  -2.981  -10.580 1.000 21.751 0 122  SER A CB   1 ? 
ATOM   1603 O OG   . SER A 1 107 ? -5.463  -1.596  -10.340 1.000 24.804 0 122  SER A OG   1 ? 
ATOM   1604 H H    . SER A 1 107 ? -5.090  -5.442  -10.307 1.000 19.425 0 122  SER A H    1 c 
ATOM   1605 H HA   . SER A 1 107 ? -4.241  -3.404  -8.838  1.000 19.700 0 122  SER A HA   1 c 
ATOM   1606 H HB2  . SER A 1 107 ? -4.505  -3.123  -11.142 1.000 21.893 0 122  SER A HB2  1 c 
ATOM   1607 H HB3  . SER A 1 107 ? -6.074  -3.338  -11.037 1.000 21.884 0 122  SER A HB3  1 c 
ATOM   1608 H HG   . SER A 1 107 ? -5.563  -1.207  -11.082 0.000 24.910 0 122  SER A HG   1 c 
ATOM   1609 N N    . ASP A 1 108 ? -7.417  -3.956  -8.412  1.000 18.573 0 123  ASP A N    1 ? 
ATOM   1610 C CA   . ASP A 1 108 ? -8.540  -3.734  -7.507  1.000 17.842 0 123  ASP A CA   1 ? 
ATOM   1611 C C    . ASP A 1 108 ? -8.174  -4.109  -6.068  1.000 18.364 0 123  ASP A C    1 ? 
ATOM   1612 O O    . ASP A 1 108 ? -8.579  -3.387  -5.143  1.000 20.072 0 123  ASP A O    1 ? 
ATOM   1613 C CB   . ASP A 1 108 ? -9.757  -4.488  -7.999  1.000 21.604 0 123  ASP A CB   1 ? 
ATOM   1614 C CG   . ASP A 1 108 ? -10.402 -3.918  -9.247  1.000 23.911 0 123  ASP A CG   1 ? 
ATOM   1615 O OD1  . ASP A 1 108 ? -10.011 -2.789  -9.697  1.000 23.907 0 123  ASP A OD1  1 ? 
ATOM   1616 O OD2  . ASP A 1 108 ? -11.276 -4.646  -9.780  1.000 25.853 0 123  ASP A OD2  1 ? 
ATOM   1617 H H    . ASP A 1 108 ? -7.527  -4.525  -9.118  1.000 18.674 0 123  ASP A H    1 c 
ATOM   1618 H HA   . ASP A 1 108 ? -8.758  -2.775  -7.525  1.000 18.792 0 123  ASP A HA   1 c 
ATOM   1619 H HB2  . ASP A 1 108 ? -9.503  -5.416  -8.183  1.000 21.135 0 123  ASP A HB2  1 c 
ATOM   1620 H HB3  . ASP A 1 108 ? -10.431 -4.497  -7.287  1.000 21.144 0 123  ASP A HB3  1 c 
ATOM   1621 N N    . VAL A 1 109 ? -7.474  -5.230  -5.883  1.000 19.582 0 124  VAL A N    1 ? 
ATOM   1622 C CA   . VAL A 1 109 ? -7.086  -5.679  -4.548  1.000 18.505 0 124  VAL A CA   1 ? 
ATOM   1623 C C    . VAL A 1 109 ? -6.172  -4.657  -3.876  1.000 18.590 0 124  VAL A C    1 ? 
ATOM   1624 O O    . VAL A 1 109 ? -6.389  -4.300  -2.722  1.000 20.211 0 124  VAL A O    1 ? 
ATOM   1625 C CB   . VAL A 1 109 ? -6.461  -7.082  -4.582  1.000 20.299 0 124  VAL A CB   1 ? 
ATOM   1626 C CG1  . VAL A 1 109 ? -5.756  -7.433  -3.267  1.000 20.645 0 124  VAL A CG1  1 ? 
ATOM   1627 C CG2  . VAL A 1 109 ? -7.546  -8.106  -4.933  1.000 22.120 0 124  VAL A CG2  1 ? 
ATOM   1628 H H    . VAL A 1 109 ? -7.235  -5.735  -6.606  1.000 19.065 0 124  VAL A H    1 c 
ATOM   1629 H HA   . VAL A 1 109 ? -7.902  -5.737  -4.014  1.000 19.070 0 124  VAL A HA   1 c 
ATOM   1630 H HB   . VAL A 1 109 ? -5.788  -7.087  -5.303  1.000 20.326 0 124  VAL A HB   1 c 
ATOM   1631 H HG11 . VAL A 1 109 ? -6.328  -7.196  -2.517  1.000 20.531 0 124  VAL A HG11 1 c 
ATOM   1632 H HG12 . VAL A 1 109 ? -4.918  -6.943  -3.204  1.000 20.529 0 124  VAL A HG12 1 c 
ATOM   1633 H HG13 . VAL A 1 109 ? -5.572  -8.388  -3.243  1.000 20.538 0 124  VAL A HG13 1 c 
ATOM   1634 H HG21 . VAL A 1 109 ? -7.143  -8.985  -5.030  1.000 21.559 0 124  VAL A HG21 1 c 
ATOM   1635 H HG22 . VAL A 1 109 ? -7.975  -7.854  -5.766  1.000 21.526 0 124  VAL A HG22 1 c 
ATOM   1636 H HG23 . VAL A 1 109 ? -8.210  -8.131  -4.223  1.000 21.559 0 124  VAL A HG23 1 c 
ATOM   1637 N N    . ILE A 1 110 ? -5.178  -4.132  -4.601  1.000 19.413 0 125  ILE A N    1 ? 
ATOM   1638 C CA   . ILE A 1 110 ? -4.302  -3.111  -4.044  1.000 18.678 0 125  ILE A CA   1 ? 
ATOM   1639 C C    . ILE A 1 110 ? -5.105  -1.861  -3.691  1.000 20.029 0 125  ILE A C    1 ? 
ATOM   1640 O O    . ILE A 1 110 ? -5.033  -1.347  -2.570  1.000 20.496 0 125  ILE A O    1 ? 
ATOM   1641 C CB   . ILE A 1 110 ? -3.130  -2.821  -5.005  1.000 19.205 0 125  ILE A CB   1 ? 
ATOM   1642 C CG1  . ILE A 1 110 ? -2.229  -4.060  -5.242  1.000 21.163 0 125  ILE A CG1  1 ? 
ATOM   1643 C CG2  . ILE A 1 110 ? -2.337  -1.622  -4.497  1.000 19.784 0 125  ILE A CG2  1 ? 
ATOM   1644 C CD1  . ILE A 1 110 ? -1.558  -4.617  -4.000  1.000 21.429 0 125  ILE A CD1  1 ? 
ATOM   1645 H H    . ILE A 1 110 ? -5.044  -4.413  -5.461  1.000 19.072 0 125  ILE A H    1 c 
ATOM   1646 H HA   . ILE A 1 110 ? -3.926  -3.464  -3.215  1.000 19.188 0 125  ILE A HA   1 c 
ATOM   1647 H HB   . ILE A 1 110 ? -3.516  -2.574  -5.868  1.000 19.561 0 125  ILE A HB   1 c 
ATOM   1648 H HG12 . ILE A 1 110 ? -2.772  -4.767  -5.644  1.000 20.726 0 125  ILE A HG12 1 c 
ATOM   1649 H HG13 . ILE A 1 110 ? -1.534  -3.818  -5.887  1.000 20.759 0 125  ILE A HG13 1 c 
ATOM   1650 H HG21 . ILE A 1 110 ? -1.479  -1.583  -4.953  1.000 19.612 0 125  ILE A HG21 1 c 
ATOM   1651 H HG22 . ILE A 1 110 ? -2.190  -1.709  -3.540  1.000 19.609 0 125  ILE A HG22 1 c 
ATOM   1652 H HG23 . ILE A 1 110 ? -2.832  -0.803  -4.674  1.000 19.614 0 125  ILE A HG23 1 c 
ATOM   1653 H HD11 . ILE A 1 110 ? -1.051  -3.912  -3.555  1.000 21.335 0 125  ILE A HD11 1 c 
ATOM   1654 H HD12 . ILE A 1 110 ? -0.953  -5.338  -4.257  1.000 21.341 0 125  ILE A HD12 1 c 
ATOM   1655 H HD13 . ILE A 1 110 ? -2.233  -4.966  -3.387  1.000 21.318 0 125  ILE A HD13 1 c 
ATOM   1656 N N    A TRP A 1 111 ? -5.912  -1.392  -4.648  0.500 19.710 0 126  TRP A N    1 ? 
ATOM   1657 N N    B TRP A 1 111 ? -5.891  -1.343  -4.642  0.500 20.514 0 126  TRP A N    1 ? 
ATOM   1658 C CA   A TRP A 1 111 ? -6.709  -0.184  -4.492  0.500 19.400 0 126  TRP A CA   1 ? 
ATOM   1659 C CA   B TRP A 1 111 ? -6.674  -0.136  -4.404  0.500 20.613 0 126  TRP A CA   1 ? 
ATOM   1660 C C    A TRP A 1 111 ? -7.611  -0.260  -3.264  0.500 20.689 0 126  TRP A C    1 ? 
ATOM   1661 C C    B TRP A 1 111 ? -7.574  -0.280  -3.183  0.500 21.359 0 126  TRP A C    1 ? 
ATOM   1662 O O    A TRP A 1 111 ? -7.685  0.700   -2.490  0.500 21.316 0 126  TRP A O    1 ? 
ATOM   1663 O O    B TRP A 1 111 ? -7.634  0.628   -2.347  0.500 21.869 0 126  TRP A O    1 ? 
ATOM   1664 C CB   A TRP A 1 111 ? -7.566  0.006   -5.753  0.500 19.744 0 126  TRP A CB   1 ? 
ATOM   1665 C CB   B TRP A 1 111 ? -7.569  0.176   -5.609  0.500 22.263 0 126  TRP A CB   1 ? 
ATOM   1666 C CG   A TRP A 1 111 ? -8.263  1.332   -5.842  0.500 20.129 0 126  TRP A CG   1 ? 
ATOM   1667 C CG   B TRP A 1 111 ? -6.950  1.055   -6.654  0.500 25.227 0 126  TRP A CG   1 ? 
ATOM   1668 C CD1  A TRP A 1 111 ? -9.486  1.694   -5.360  0.500 24.327 0 126  TRP A CD1  1 ? 
ATOM   1669 C CD1  B TRP A 1 111 ? -5.963  0.751   -7.548  0.500 25.494 0 126  TRP A CD1  1 ? 
ATOM   1670 C CD2  A TRP A 1 111 ? -7.730  2.497   -6.503  0.500 22.657 0 126  TRP A CD2  1 ? 
ATOM   1671 C CD2  B TRP A 1 111 ? -7.408  2.380   -6.986  0.500 23.513 0 126  TRP A CD2  1 ? 
ATOM   1672 N NE1  A TRP A 1 111 ? -9.763  2.999   -5.692  0.500 26.916 0 126  TRP A NE1  1 ? 
ATOM   1673 N NE1  B TRP A 1 111 ? -5.743  1.824   -8.373  0.500 25.348 0 126  TRP A NE1  1 ? 
ATOM   1674 C CE2  A TRP A 1 111 ? -8.700  3.517   -6.390  0.500 27.934 0 126  TRP A CE2  1 ? 
ATOM   1675 C CE2  B TRP A 1 111 ? -6.626  2.824   -8.070  0.500 23.948 0 126  TRP A CE2  1 ? 
ATOM   1676 C CE3  A TRP A 1 111 ? -6.548  2.763   -7.194  0.500 25.956 0 126  TRP A CE3  1 ? 
ATOM   1677 C CE3  B TRP A 1 111 ? -8.395  3.223   -6.477  0.500 27.556 0 126  TRP A CE3  1 ? 
ATOM   1678 C CZ2  A TRP A 1 111 ? -8.499  4.785   -6.930  0.500 28.725 0 126  TRP A CZ2  1 ? 
ATOM   1679 C CZ2  B TRP A 1 111 ? -6.799  4.083   -8.639  0.500 24.111 0 126  TRP A CZ2  1 ? 
ATOM   1680 C CZ3  A TRP A 1 111 ? -6.360  4.010   -7.739  0.500 27.481 0 126  TRP A CZ3  1 ? 
ATOM   1681 C CZ3  B TRP A 1 111 ? -8.582  4.455   -7.061  0.500 26.495 0 126  TRP A CZ3  1 ? 
ATOM   1682 C CH2  A TRP A 1 111 ? -7.329  5.008   -7.618  0.500 28.724 0 126  TRP A CH2  1 ? 
ATOM   1683 C CH2  B TRP A 1 111 ? -7.801  4.873   -8.133  0.500 24.985 0 126  TRP A CH2  1 ? 
ATOM   1684 H H    A TRP A 1 111 ? -5.966  -1.846  -5.440  0.500 19.706 0 126  TRP A H    1 c 
ATOM   1685 H H    B TRP A 1 111 ? -5.939  -1.747  -5.461  0.500 20.401 0 126  TRP A H    1 c 
ATOM   1686 H HA   A TRP A 1 111 ? -6.096  0.594   -4.399  0.500 19.752 0 126  TRP A HA   1 c 
ATOM   1687 H HA   B TRP A 1 111 ? -6.052  0.626   -4.261  0.500 21.020 0 126  TRP A HA   1 c 
ATOM   1688 H HB2  A TRP A 1 111 ? -6.989  -0.101  -6.539  0.500 19.746 0 126  TRP A HB2  1 c 
ATOM   1689 H HB2  B TRP A 1 111 ? -7.833  -0.672  -6.026  0.500 22.523 0 126  TRP A HB2  1 c 
ATOM   1690 H HB3  A TRP A 1 111 ? -8.240  -0.707  -5.781  0.500 19.762 0 126  TRP A HB3  1 c 
ATOM   1691 H HB3  B TRP A 1 111 ? -8.388  0.606   -5.282  0.500 22.523 0 126  TRP A HB3  1 c 
ATOM   1692 H HD1  A TRP A 1 111 ? -10.074 1.129   -4.883  0.500 23.858 0 126  TRP A HD1  1 c 
ATOM   1693 H HD1  B TRP A 1 111 ? -5.469  -0.051  -7.574  0.500 25.303 0 126  TRP A HD1  1 c 
ATOM   1694 H HE1  A TRP A 1 111 ? -10.488 3.433   -5.473  0.500 26.437 0 126  TRP A HE1  1 c 
ATOM   1695 H HE1  B TRP A 1 111 ? -5.145  1.852   -9.007  0.500 25.067 0 126  TRP A HE1  1 c 
ATOM   1696 H HE3  A TRP A 1 111 ? -5.891  2.094   -7.289  0.500 25.524 0 126  TRP A HE3  1 c 
ATOM   1697 H HE3  B TRP A 1 111 ? -8.938  2.944   -5.759  0.500 26.290 0 126  TRP A HE3  1 c 
ATOM   1698 H HZ2  A TRP A 1 111 ? -9.155  5.455   -6.853  0.500 28.460 0 126  TRP A HZ2  1 c 
ATOM   1699 H HZ2  B TRP A 1 111 ? -6.277  4.362   -9.371  0.500 24.312 0 126  TRP A HZ2  1 c 
ATOM   1700 H HZ3  A TRP A 1 111 ? -5.561  4.196   -8.202  0.500 27.316 0 126  TRP A HZ3  1 c 
ATOM   1701 H HZ3  B TRP A 1 111 ? -9.246  5.032   -6.722  0.500 26.329 0 126  TRP A HZ3  1 c 
ATOM   1702 H HH2  A TRP A 1 111 ? -7.166  5.857   -7.988  0.500 28.364 0 126  TRP A HH2  1 c 
ATOM   1703 H HH2  B TRP A 1 111 ? -7.939  5.730   -8.497  0.500 25.121 0 126  TRP A HH2  1 c 
ATOM   1704 N N    . ASN A 1 112 ? -8.320  -1.389  -3.137  1.000 21.905 0 127  ASN A N    1 ? 
ATOM   1705 C CA   . ASN A 1 112 ? -9.334  -1.594  -2.107  1.000 24.266 0 127  ASN A CA   1 ? 
ATOM   1706 C C    . ASN A 1 112 ? -8.697  -1.744  -0.722  1.000 23.778 0 127  ASN A C    1 ? 
ATOM   1707 O O    . ASN A 1 112 ? -9.401  -1.683  0.289   1.000 25.992 0 127  ASN A O    1 ? 
ATOM   1708 C CB   . ASN A 1 112 ? -10.238 -2.770  -2.447  1.000 29.090 0 127  ASN A CB   1 ? 
ATOM   1709 C CG   . ASN A 1 112 ? -11.199 -2.433  -3.572  1.000 37.581 0 127  ASN A CG   1 ? 
ATOM   1710 O OD1  . ASN A 1 112 ? -11.426 -1.257  -3.866  1.000 37.915 0 127  ASN A OD1  1 ? 
ATOM   1711 N ND2  . ASN A 1 112 ? -11.756 -3.440  -4.232  1.000 40.933 0 127  ASN A ND2  1 ? 
ATOM   1712 H H    . ASN A 1 112 ? -8.183  -2.056  -3.747  1.000 21.998 0 127  ASN A H    1 c 
ATOM   1713 H HA   . ASN A 1 112 ? -9.901  -0.790  -2.084  1.000 24.572 0 127  ASN A HA   1 c 
ATOM   1714 H HB2  . ASN A 1 112 ? -9.688  -3.534  -2.711  1.000 29.530 0 127  ASN A HB2  1 c 
ATOM   1715 H HB3  . ASN A 1 112 ? -10.749 -3.023  -1.653  1.000 29.537 0 127  ASN A HB3  1 c 
ATOM   1716 H HD21 . ASN A 1 112 ? -11.560 -4.277  -4.013  1.000 39.684 0 127  ASN A HD21 1 c 
ATOM   1717 H HD22 . ASN A 1 112 ? -12.324 -3.275  -4.894  1.000 39.812 0 127  ASN A HD22 1 c 
ATOM   1718 N N    . SER A 1 113 ? -7.389  -1.981  -0.663  1.000 21.007 0 128  SER A N    1 ? 
ATOM   1719 C CA   . SER A 1 113 ? -6.655  -2.074  0.596   1.000 21.224 0 128  SER A CA   1 ? 
ATOM   1720 C C    . SER A 1 113 ? -6.275  -0.707  1.181   1.000 22.784 0 128  SER A C    1 ? 
ATOM   1721 O O    . SER A 1 113 ? -5.838  -0.652  2.333   1.000 24.689 0 128  SER A O    1 ? 
ATOM   1722 C CB   . SER A 1 113 ? -5.425  -2.868  0.392   1.000 22.215 0 128  SER A CB   1 ? 
ATOM   1723 O OG   . SER A 1 113 ? -5.677  -4.196  -0.057  1.000 25.366 0 128  SER A OG   1 ? 
ATOM   1724 H H    . SER A 1 113 ? -6.929  -2.126  -1.438  1.000 21.698 0 128  SER A H    1 c 
ATOM   1725 H HA   . SER A 1 113 ? -7.226  -2.546  1.254   1.000 21.675 0 128  SER A HA   1 c 
ATOM   1726 H HB2  . SER A 1 113 ? -4.860  -2.415  -0.259  1.000 22.644 0 128  SER A HB2  1 c 
ATOM   1727 H HB3  . SER A 1 113 ? -4.932  -2.908  1.233   1.000 22.685 0 128  SER A HB3  1 c 
ATOM   1728 H HG   . SER A 1 113 ? -4.936  -4.595  -0.150  0.000 25.360 0 128  SER A HG   1 c 
ATOM   1729 N N    . LEU A 1 114 ? -6.323  0.362   0.389   1.000 18.818 0 129  LEU A N    1 ? 
ATOM   1730 C CA   . LEU A 1 114 ? -5.775  1.645   0.778   1.000 19.773 0 129  LEU A CA   1 ? 
ATOM   1731 C C    . LEU A 1 114 ? -6.764  2.367   1.692   1.000 22.768 0 129  LEU A C    1 ? 
ATOM   1732 O O    . LEU A 1 114 ? -7.960  2.213   1.525   1.000 25.147 0 129  LEU A O    1 ? 
ATOM   1733 C CB   . LEU A 1 114 ? -5.431  2.484   -0.434  1.000 20.189 0 129  LEU A CB   1 ? 
ATOM   1734 C CG   . LEU A 1 114 ? -4.431  1.862   -1.413  1.000 21.539 0 129  LEU A CG   1 ? 
ATOM   1735 C CD1  . LEU A 1 114 ? -4.361  2.742   -2.664  1.000 24.585 0 129  LEU A CD1  1 ? 
ATOM   1736 C CD2  . LEU A 1 114 ? -3.078  1.706   -0.763  1.000 23.208 0 129  LEU A CD2  1 ? 
ATOM   1737 H H    . LEU A 1 114 ? -6.716  0.289   -0.433  1.000 19.961 0 129  LEU A H    1 c 
ATOM   1738 H HA   . LEU A 1 114 ? -4.947  1.478   1.293   1.000 20.271 0 129  LEU A HA   1 c 
ATOM   1739 H HB2  . LEU A 1 114 ? -6.266  2.676   -0.921  1.000 20.430 0 129  LEU A HB2  1 c 
ATOM   1740 H HB3  . LEU A 1 114 ? -5.065  3.343   -0.120  1.000 20.397 0 129  LEU A HB3  1 c 
ATOM   1741 H HG   . LEU A 1 114 ? -4.763  0.966   -1.675  1.000 22.088 0 129  LEU A HG   1 c 
ATOM   1742 H HD11 . LEU A 1 114 ? -5.239  2.785   -3.080  1.000 23.625 0 129  LEU A HD11 1 c 
ATOM   1743 H HD12 . LEU A 1 114 ? -3.724  2.363   -3.293  1.000 23.643 0 129  LEU A HD12 1 c 
ATOM   1744 H HD13 . LEU A 1 114 ? -4.077  3.638   -2.416  1.000 23.642 0 129  LEU A HD13 1 c 
ATOM   1745 H HD21 . LEU A 1 114 ? -3.127  1.033   -0.064  1.000 22.665 0 129  LEU A HD21 1 c 
ATOM   1746 H HD22 . LEU A 1 114 ? -2.803  2.555   -0.377  1.000 22.691 0 129  LEU A HD22 1 c 
ATOM   1747 H HD23 . LEU A 1 114 ? -2.428  1.429   -1.431  1.000 22.691 0 129  LEU A HD23 1 c 
ATOM   1748 N N    . SER A 1 115 ? -6.234  3.169   2.613   1.000 23.811 0 130  SER A N    1 ? 
ATOM   1749 C CA   . SER A 1 115 ? -7.030  4.093   3.404   1.000 28.408 0 130  SER A CA   1 ? 
ATOM   1750 C C    . SER A 1 115 ? -7.874  4.946   2.474   1.000 33.043 0 130  SER A C    1 ? 
ATOM   1751 O O    . SER A 1 115 ? -7.366  5.408   1.452   1.000 34.496 0 130  SER A O    1 ? 
ATOM   1752 C CB   . SER A 1 115 ? -6.150  4.973   4.232   1.000 27.840 0 130  SER A CB   1 ? 
ATOM   1753 O OG   . SER A 1 115 ? -5.473  4.179   5.188   1.000 31.135 0 130  SER A OG   1 ? 
ATOM   1754 H H    . SER A 1 115 ? -5.332  3.140   2.756   1.000 24.466 0 130  SER A H    1 c 
ATOM   1755 H HA   . SER A 1 115 ? -7.627  3.573   4.000   1.000 28.261 0 130  SER A HA   1 c 
ATOM   1756 H HB2  . SER A 1 115 ? -5.501  5.422   3.658   1.000 28.726 0 130  SER A HB2  1 c 
ATOM   1757 H HB3  . SER A 1 115 ? -6.691  5.648   4.685   1.000 28.744 0 130  SER A HB3  1 c 
ATOM   1758 H HG   . SER A 1 115 ? -4.975  4.680   5.652   0.000 31.060 0 130  SER A HG   1 c 
ATOM   1759 N N    . ARG A 1 116 ? -9.112  5.231   2.914   1.000 42.026 0 131  ARG A N    1 ? 
ATOM   1760 C CA   . ARG A 1 116 ? -10.097 5.940   2.112   1.000 51.732 0 131  ARG A CA   1 ? 
ATOM   1761 C C    . ARG A 1 116 ? -9.633  7.374   1.877   1.000 49.321 0 131  ARG A C    1 ? 
ATOM   1762 O O    . ARG A 1 116 ? -9.778  7.918   0.781   1.000 54.680 0 131  ARG A O    1 ? 
ATOM   1763 C CB   . ARG A 1 116 ? -11.475 5.959   2.790   1.000 57.427 0 131  ARG A CB   1 ? 
ATOM   1764 C CG   . ARG A 1 116 ? -12.624 6.101   1.798   1.000 68.401 0 131  ARG A CG   1 ? 
ATOM   1765 C CD   . ARG A 1 116 ? -13.893 6.701   2.411   1.000 81.840 0 131  ARG A CD   1 ? 
ATOM   1766 N NE   . ARG A 1 116 ? -15.124 6.169   1.810   1.000 93.346 0 131  ARG A NE   1 ? 
ATOM   1767 C CZ   . ARG A 1 116 ? -16.372 6.492   2.152   1.000 95.725 0 131  ARG A CZ   1 ? 
ATOM   1768 N NH1  . ARG A 1 116 ? -17.386 5.793   1.663   1.000 91.123 0 131  ARG A NH1  1 ? 
ATOM   1769 N NH2  . ARG A 1 116 ? -16.603 7.477   3.006   1.000 94.037 0 131  ARG A NH2  1 ? 
ATOM   1770 H H    . ARG A 1 116 ? -9.347  4.973   3.759   1.000 41.548 0 131  ARG A H    1 c 
ATOM   1771 H HA   . ARG A 1 116 ? -10.174 5.482   1.236   1.000 50.257 0 131  ARG A HA   1 c 
ATOM   1772 H HB2  . ARG A 1 116 ? -11.595 5.127   3.294   1.000 58.222 0 131  ARG A HB2  1 c 
ATOM   1773 H HB3  . ARG A 1 116 ? -11.510 6.705   3.427   1.000 58.519 0 131  ARG A HB3  1 c 
ATOM   1774 H HG2  . ARG A 1 116 ? -12.334 6.669   1.052   1.000 68.282 0 131  ARG A HG2  1 c 
ATOM   1775 H HG3  . ARG A 1 116 ? -12.836 5.216   1.431   1.000 68.557 0 131  ARG A HG3  1 c 
ATOM   1776 H HD2  . ARG A 1 116 ? -13.901 6.520   3.373   1.000 80.780 0 131  ARG A HD2  1 c 
ATOM   1777 H HD3  . ARG A 1 116 ? -13.871 7.673   2.289   1.000 81.105 0 131  ARG A HD3  1 c 
ATOM   1778 H HE   . ARG A 1 116 ? -15.035 5.589   1.166   1.000 90.708 0 131  ARG A HE   1 c 
ATOM   1779 H HH11 . ARG A 1 116 ? -18.215 6.083   1.775   1.000 92.540 0 131  ARG A HH11 1 c 
ATOM   1780 H HH12 . ARG A 1 116 ? -17.234 5.039   1.226   1.000 92.511 0 131  ARG A HH12 1 c 
ATOM   1781 H HH21 . ARG A 1 116 ? -17.396 7.537   3.400   1.000 94.459 0 131  ARG A HH21 1 c 
ATOM   1782 H HH22 . ARG A 1 116 ? -15.973 8.074   3.180   1.000 94.322 0 131  ARG A HH22 1 c 
ATOM   1783 N N    . SER A 1 117 ? -9.059  7.980   2.918   1.000 42.620 0 132  SER A N    1 ? 
ATOM   1784 C CA   . SER A 1 117 ? -8.622  9.353   2.814   1.000 45.318 0 132  SER A CA   1 ? 
ATOM   1785 C C    . SER A 1 117 ? -7.216  9.459   3.386   1.000 38.915 0 132  SER A C    1 ? 
ATOM   1786 O O    . SER A 1 117 ? -6.973  9.015   4.499   1.000 40.397 0 132  SER A O    1 ? 
ATOM   1787 C CB   . SER A 1 117 ? -9.575  10.291  3.529   1.000 48.081 0 132  SER A CB   1 ? 
ATOM   1788 O OG   . SER A 1 117 ? -9.324  11.628  3.121   1.000 54.356 0 132  SER A OG   1 ? 
ATOM   1789 H H    . SER A 1 117 ? -8.947  7.534   3.707   1.000 44.730 0 132  SER A H    1 c 
ATOM   1790 H HA   . SER A 1 117 ? -8.591  9.604   1.857   1.000 43.998 0 132  SER A HA   1 c 
ATOM   1791 H HB2  . SER A 1 117 ? -10.495 10.049  3.314   1.000 48.844 0 132  SER A HB2  1 c 
ATOM   1792 H HB3  . SER A 1 117 ? -9.450  10.213  4.494   1.000 48.796 0 132  SER A HB3  1 c 
ATOM   1793 H HG   . SER A 1 117 ? -9.892  12.124  3.524   0.000 54.990 0 132  SER A HG   1 c 
ATOM   1794 N N    . TYR A 1 118 ? -6.306  10.043  2.592   1.000 36.401 0 133  TYR A N    1 ? 
ATOM   1795 C CA   . TYR A 1 118 ? -4.999  10.455  3.092   1.000 31.819 0 133  TYR A CA   1 ? 
ATOM   1796 C C    . TYR A 1 118 ? -4.385  11.458  2.116   1.000 34.235 0 133  TYR A C    1 ? 
ATOM   1797 O O    . TYR A 1 118 ? -4.909  11.630  1.017   1.000 33.246 0 133  TYR A O    1 ? 
ATOM   1798 C CB   . TYR A 1 118 ? -4.067  9.258   3.290   1.000 32.835 0 133  TYR A CB   1 ? 
ATOM   1799 C CG   . TYR A 1 118 ? -3.787  8.400   2.057   1.000 28.766 0 133  TYR A CG   1 ? 
ATOM   1800 C CD1  . TYR A 1 118 ? -4.666  7.381   1.712   1.000 29.009 0 133  TYR A CD1  1 ? 
ATOM   1801 C CD2  . TYR A 1 118 ? -2.650  8.579   1.264   1.000 29.570 0 133  TYR A CD2  1 ? 
ATOM   1802 C CE1  . TYR A 1 118 ? -4.410  6.546   0.638   1.000 27.263 0 133  TYR A CE1  1 ? 
ATOM   1803 C CE2  . TYR A 1 118 ? -2.395  7.765   0.157   1.000 27.693 0 133  TYR A CE2  1 ? 
ATOM   1804 C CZ   . TYR A 1 118 ? -3.253  6.708   -0.120  1.000 27.041 0 133  TYR A CZ   1 ? 
ATOM   1805 O OH   . TYR A 1 118 ? -3.104  5.833   -1.179  1.000 23.421 0 133  TYR A OH   1 ? 
ATOM   1806 H H    . TYR A 1 118 ? -6.504  10.185  1.711   1.000 35.994 0 133  TYR A H    1 c 
ATOM   1807 H HA   . TYR A 1 118 ? -5.127  10.904  3.967   1.000 33.426 0 133  TYR A HA   1 c 
ATOM   1808 H HB2  . TYR A 1 118 ? -3.211  9.593   3.635   1.000 31.763 0 133  TYR A HB2  1 c 
ATOM   1809 H HB3  . TYR A 1 118 ? -4.452  8.683   3.988   1.000 31.726 0 133  TYR A HB3  1 c 
ATOM   1810 H HD1  . TYR A 1 118 ? -5.426  7.224   2.248   1.000 28.537 0 133  TYR A HD1  1 c 
ATOM   1811 H HD2  . TYR A 1 118 ? -2.040  9.266   1.480   1.000 28.923 0 133  TYR A HD2  1 c 
ATOM   1812 H HE1  . TYR A 1 118 ? -5.005  5.846   0.436   1.000 27.646 0 133  TYR A HE1  1 c 
ATOM   1813 H HE2  . TYR A 1 118 ? -1.609  7.883   -0.348  1.000 27.949 0 133  TYR A HE2  1 c 
ATOM   1814 H HH   . TYR A 1 118 ? -3.463  6.163   -1.885  0.000 23.430 0 133  TYR A HH   1 c 
ATOM   1815 N N    . PHE A 1 119 ? -3.271  12.099  2.514   1.000 34.244 0 134  PHE A N    1 ? 
ATOM   1816 C CA   . PHE A 1 119 ? -2.545  13.031  1.644   1.000 37.827 0 134  PHE A CA   1 ? 
ATOM   1817 C C    . PHE A 1 119 ? -1.670  12.226  0.688   1.000 37.779 0 134  PHE A C    1 ? 
ATOM   1818 O O    . PHE A 1 119 ? -0.652  11.651  1.107   1.000 37.706 0 134  PHE A O    1 ? 
ATOM   1819 C CB   . PHE A 1 119 ? -1.637  14.019  2.385   1.000 42.714 0 134  PHE A CB   1 ? 
ATOM   1820 C CG   . PHE A 1 119 ? -2.369  14.854  3.420   1.000 45.021 0 134  PHE A CG   1 ? 
ATOM   1821 C CD1  . PHE A 1 119 ? -2.960  16.063  3.061   1.000 50.717 0 134  PHE A CD1  1 ? 
ATOM   1822 C CD2  . PHE A 1 119 ? -2.503  14.397  4.731   1.000 44.842 0 134  PHE A CD2  1 ? 
ATOM   1823 C CE1  . PHE A 1 119 ? -3.651  16.820  3.999   1.000 48.670 0 134  PHE A CE1  1 ? 
ATOM   1824 C CE2  . PHE A 1 119 ? -3.188  15.163  5.668   1.000 52.137 0 134  PHE A CE2  1 ? 
ATOM   1825 C CZ   . PHE A 1 119 ? -3.764  16.368  5.295   1.000 46.808 0 134  PHE A CZ   1 ? 
ATOM   1826 H H    . PHE A 1 119 ? -2.950  11.948  3.356   1.000 35.012 0 134  PHE A H    1 c 
ATOM   1827 H HA   . PHE A 1 119 ? -3.208  13.550  1.115   1.000 37.882 0 134  PHE A HA   1 c 
ATOM   1828 H HB2  . PHE A 1 119 ? -0.927  13.514  2.834   1.000 42.035 0 134  PHE A HB2  1 c 
ATOM   1829 H HB3  . PHE A 1 119 ? -1.219  14.617  1.726   1.000 42.029 0 134  PHE A HB3  1 c 
ATOM   1830 H HD1  . PHE A 1 119 ? -2.886  16.372  2.172   1.000 48.807 0 134  PHE A HD1  1 c 
ATOM   1831 H HD2  . PHE A 1 119 ? -2.107  13.582  4.985   1.000 46.772 0 134  PHE A HD2  1 c 
ATOM   1832 H HE1  . PHE A 1 119 ? -4.040  17.642  3.748   1.000 48.659 0 134  PHE A HE1  1 c 
ATOM   1833 H HE2  . PHE A 1 119 ? -3.267  14.858  6.558   1.000 49.056 0 134  PHE A HE2  1 c 
ATOM   1834 H HZ   . PHE A 1 119 ? -4.228  16.884  5.934   1.000 48.407 0 134  PHE A HZ   1 c 
ATOM   1835 N N    . LYS A 1 120 ? -2.085  12.186  -0.595  1.000 37.075 0 135  LYS A N    1 ? 
ATOM   1836 C CA   . LYS A 1 120 ? -1.589  11.215  -1.564  1.000 41.188 0 135  LYS A CA   1 ? 
ATOM   1837 C C    . LYS A 1 120 ? -0.219  11.623  -2.119  1.000 40.534 0 135  LYS A C    1 ? 
ATOM   1838 O O    . LYS A 1 120 ? 0.392   10.836  -2.857  1.000 38.709 0 135  LYS A O    1 ? 
ATOM   1839 C CB   . LYS A 1 120 ? -2.693  10.973  -2.608  1.000 43.044 0 135  LYS A CB   1 ? 
ATOM   1840 C CG   . LYS A 1 120 ? -3.724  9.954   -2.102  1.000 56.079 0 135  LYS A CG   1 ? 
ATOM   1841 C CD   . LYS A 1 120 ? -5.201  10.133  -2.446  1.000 62.447 0 135  LYS A CD   1 ? 
ATOM   1842 C CE   . LYS A 1 120 ? -6.028  9.233   -1.551  1.000 69.194 0 135  LYS A CE   1 ? 
ATOM   1843 N NZ   . LYS A 1 120 ? -7.486  9.372   -1.675  1.000 75.345 0 135  LYS A NZ   1 ? 
ATOM   1844 H H    . LYS A 1 120 ? -2.702  12.800  -0.874  1.000 38.218 0 135  LYS A H    1 c 
ATOM   1845 H HA   . LYS A 1 120 ? -1.461  10.357  -1.084  1.000 40.689 0 135  LYS A HA   1 c 
ATOM   1846 H HB2  . LYS A 1 120 ? -3.150  11.818  -2.810  1.000 45.152 0 135  LYS A HB2  1 c 
ATOM   1847 H HB3  . LYS A 1 120 ? -2.291  10.636  -3.437  1.000 45.220 0 135  LYS A HB3  1 c 
ATOM   1848 H HG2  . LYS A 1 120 ? -3.446  9.070   -2.427  1.000 54.049 0 135  LYS A HG2  1 c 
ATOM   1849 H HG3  . LYS A 1 120 ? -3.648  9.923   -1.124  1.000 53.883 0 135  LYS A HG3  1 c 
ATOM   1850 H HD2  . LYS A 1 120 ? -5.464  11.068  -2.303  1.000 62.320 0 135  LYS A HD2  1 c 
ATOM   1851 H HD3  . LYS A 1 120 ? -5.353  9.899   -3.384  1.000 62.004 0 135  LYS A HD3  1 c 
ATOM   1852 H HE2  . LYS A 1 120 ? -5.788  8.306   -1.728  1.000 68.653 0 135  LYS A HE2  1 c 
ATOM   1853 H HE3  . LYS A 1 120 ? -5.789  9.418   -0.625  1.000 68.723 0 135  LYS A HE3  1 c 
ATOM   1854 H HZ1  . LYS A 1 120 ? -7.714  9.629   -2.516  1.000 72.847 0 135  LYS A HZ1  1 c 
ATOM   1855 H HZ2  . LYS A 1 120 ? -7.772  10.011  -1.090  1.000 73.229 0 135  LYS A HZ2  1 c 
ATOM   1856 H HZ3  . LYS A 1 120 ? -7.892  8.583   -1.471  1.000 73.070 0 135  LYS A HZ3  1 c 
ATOM   1857 N N    . ASP A 1 121 ? 0.245   12.821  -1.714  1.000 39.205 0 136  ASP A N    1 ? 
ATOM   1858 C CA   . ASP A 1 121 ? 1.500   13.443  -2.129  1.000 44.304 0 136  ASP A CA   1 ? 
ATOM   1859 C C    . ASP A 1 121 ? 2.515   13.494  -0.988  1.000 39.218 0 136  ASP A C    1 ? 
ATOM   1860 O O    . ASP A 1 121 ? 3.490   14.241  -1.046  1.000 42.784 0 136  ASP A O    1 ? 
ATOM   1861 C CB   . ASP A 1 121 ? 1.337   14.921  -2.445  1.000 48.809 0 136  ASP A CB   1 ? 
ATOM   1862 C CG   . ASP A 1 121 ? 0.294   15.258  -3.496  1.000 63.883 0 136  ASP A CG   1 ? 
ATOM   1863 O OD1  . ASP A 1 121 ? 0.321   14.602  -4.567  1.000 62.138 0 136  ASP A OD1  1 ? 
ATOM   1864 O OD2  . ASP A 1 121 ? -0.523  16.178  -3.230  1.000 78.208 0 136  ASP A OD2  1 ? 
ATOM   1865 H H    . ASP A 1 121 ? -0.278  13.299  -1.138  1.000 40.587 0 136  ASP A H    1 c 
ATOM   1866 H HA   . ASP A 1 121 ? 1.876   12.953  -2.895  1.000 43.027 0 136  ASP A HA   1 c 
ATOM   1867 H HB2  . ASP A 1 121 ? 1.102   15.400  -1.622  1.000 50.819 0 136  ASP A HB2  1 c 
ATOM   1868 H HB3  . ASP A 1 121 ? 2.192   15.277  -2.766  1.000 50.721 0 136  ASP A HB3  1 c 
ATOM   1869 N N    . ARG A 1 122 ? 2.271   12.748  0.077   1.000 37.622 0 137  ARG A N    1 ? 
ATOM   1870 C CA   . ARG A 1 122 ? 3.228   12.679  1.160   1.000 32.083 0 137  ARG A CA   1 ? 
ATOM   1871 C C    . ARG A 1 122 ? 4.505   11.992  0.680   1.000 29.612 0 137  ARG A C    1 ? 
ATOM   1872 O O    . ARG A 1 122 ? 4.501   11.220  -0.275  1.000 26.457 0 137  ARG A O    1 ? 
ATOM   1873 C CB   . ARG A 1 122 ? 2.717   11.806  2.312   1.000 36.762 0 137  ARG A CB   1 ? 
ATOM   1874 C CG   . ARG A 1 122 ? 1.619   12.370  3.184   1.000 44.985 0 137  ARG A CG   1 ? 
ATOM   1875 C CD   . ARG A 1 122 ? 0.927   11.230  3.947   1.000 51.993 0 137  ARG A CD   1 ? 
ATOM   1876 N NE   . ARG A 1 122 ? 1.591   10.991  5.225   1.000 53.317 0 137  ARG A NE   1 ? 
ATOM   1877 C CZ   . ARG A 1 122 ? 1.567   11.847  6.249   1.000 65.177 0 137  ARG A CZ   1 ? 
ATOM   1878 N NH1  . ARG A 1 122 ? 2.530   11.793  7.146   1.000 67.837 0 137  ARG A NH1  1 ? 
ATOM   1879 N NH2  . ARG A 1 122 ? 0.672   12.826  6.328   1.000 70.216 0 137  ARG A NH2  1 ? 
ATOM   1880 H H    . ARG A 1 122 ? 1.496   12.268  0.137   1.000 36.741 0 137  ARG A H    1 c 
ATOM   1881 H HA   . ARG A 1 122 ? 3.433   13.596  1.476   1.000 33.435 0 137  ARG A HA   1 c 
ATOM   1882 H HB2  . ARG A 1 122 ? 2.399   10.962  1.925   1.000 37.474 0 137  ARG A HB2  1 c 
ATOM   1883 H HB3  . ARG A 1 122 ? 3.480   11.589  2.889   1.000 37.248 0 137  ARG A HB3  1 c 
ATOM   1884 H HG2  . ARG A 1 122 ? 2.001   13.009  3.824   1.000 44.488 0 137  ARG A HG2  1 c 
ATOM   1885 H HG3  . ARG A 1 122 ? 0.964   12.837  2.626   1.000 44.319 0 137  ARG A HG3  1 c 
ATOM   1886 H HD2  . ARG A 1 122 ? -0.007  11.466  4.102   1.000 50.803 0 137  ARG A HD2  1 c 
ATOM   1887 H HD3  . ARG A 1 122 ? 0.946   10.409  3.414   1.000 50.475 0 137  ARG A HD3  1 c 
ATOM   1888 H HE   . ARG A 1 122 ? 2.027   10.244  5.327   1.000 55.756 0 137  ARG A HE   1 c 
ATOM   1889 H HH11 . ARG A 1 122 ? 2.448   12.231  7.910   1.000 66.992 0 137  ARG A HH11 1 c 
ATOM   1890 H HH12 . ARG A 1 122 ? 3.259   11.318  6.982   1.000 66.796 0 137  ARG A HH12 1 c 
ATOM   1891 H HH21 . ARG A 1 122 ? 0.773   13.463  6.935   1.000 68.479 0 137  ARG A HH21 1 c 
ATOM   1892 H HH22 . ARG A 1 122 ? -0.024  12.842  5.784   1.000 68.082 0 137  ARG A HH22 1 c 
ATOM   1893 N N    . ALA A 1 123 ? 5.573   12.233  1.429   1.000 24.928 0 138  ALA A N    1 ? 
ATOM   1894 C CA   . ALA A 1 123 ? 6.803   11.473  1.320   1.000 22.692 0 138  ALA A CA   1 ? 
ATOM   1895 C C    . ALA A 1 123 ? 6.662   10.152  2.069   1.000 19.647 0 138  ALA A C    1 ? 
ATOM   1896 O O    . ALA A 1 123 ? 5.855   9.990   3.006   1.000 21.413 0 138  ALA A O    1 ? 
ATOM   1897 C CB   . ALA A 1 123 ? 7.924   12.314  1.893   1.000 23.260 0 138  ALA A CB   1 ? 
ATOM   1898 H H    . ALA A 1 123 ? 5.534   12.908  2.044   1.000 25.488 0 138  ALA A H    1 c 
ATOM   1899 H HA   . ALA A 1 123 ? 6.982   11.283  0.357   1.000 22.637 0 138  ALA A HA   1 c 
ATOM   1900 H HB1  . ALA A 1 123 ? 7.990   13.150  1.402   1.000 23.094 0 138  ALA A HB1  1 c 
ATOM   1901 H HB2  . ALA A 1 123 ? 7.745   12.504  2.829   1.000 23.106 0 138  ALA A HB2  1 c 
ATOM   1902 H HB3  . ALA A 1 123 ? 8.765   11.832  1.819   1.000 23.095 0 138  ALA A HB3  1 c 
ATOM   1903 N N    . HIS A 1 124 ? 7.450   9.161   1.642   1.000 19.162 0 139  HIS A N    1 ? 
ATOM   1904 C CA   . HIS A 1 124 ? 7.648   7.913   2.347   1.000 17.712 0 139  HIS A CA   1 ? 
ATOM   1905 C C    . HIS A 1 124 ? 6.414   7.024   2.264   1.000 17.548 0 139  HIS A C    1 ? 
ATOM   1906 O O    . HIS A 1 124 ? 6.233   6.181   3.122   1.000 19.385 0 139  HIS A O    1 ? 
ATOM   1907 C CB   . HIS A 1 124 ? 8.143   8.129   3.791   1.000 18.192 0 139  HIS A CB   1 ? 
ATOM   1908 C CG   . HIS A 1 124 ? 9.192   9.171   3.920   1.000 18.482 0 139  HIS A CG   1 ? 
ATOM   1909 N ND1  . HIS A 1 124 ? 10.455  9.058   3.368   1.000 18.033 0 139  HIS A ND1  1 ? 
ATOM   1910 C CD2  . HIS A 1 124 ? 9.173   10.337  4.610   1.000 21.620 0 139  HIS A CD2  1 ? 
ATOM   1911 C CE1  . HIS A 1 124 ? 11.154  10.162  3.681   1.000 19.706 0 139  HIS A CE1  1 ? 
ATOM   1912 N NE2  . HIS A 1 124 ? 10.396  10.945  4.449   1.000 21.301 0 139  HIS A NE2  1 ? 
ATOM   1913 H H    . HIS A 1 124 ? 7.894   9.278   0.852   1.000 18.985 0 139  HIS A H    1 c 
ATOM   1914 H HA   . HIS A 1 124 ? 8.378   7.449   1.870   1.000 18.043 0 139  HIS A HA   1 c 
ATOM   1915 H HB2  . HIS A 1 124 ? 7.377   8.377   4.353   1.000 18.168 0 139  HIS A HB2  1 c 
ATOM   1916 H HB3  . HIS A 1 124 ? 8.497   7.279   4.131   1.000 18.160 0 139  HIS A HB3  1 c 
ATOM   1917 H HD1  . HIS A 1 124 ? 10.747  8.371   2.898   0.000 17.980 0 139  HIS A HD1  1 c 
ATOM   1918 H HD2  . HIS A 1 124 ? 8.452   10.684  5.098   1.000 20.750 0 139  HIS A HD2  1 c 
ATOM   1919 H HE1  . HIS A 1 124 ? 12.040  10.338  3.424   1.000 19.699 0 139  HIS A HE1  1 c 
ATOM   1920 H HE2  . HIS A 1 124 ? 10.631  11.721  4.778   0.000 21.240 0 139  HIS A HE2  1 c 
ATOM   1921 N N    . ILE A 1 125 ? 5.579   7.205   1.211   1.000 16.543 0 140  ILE A N    1 ? 
ATOM   1922 C CA   . ILE A 1 125 ? 4.469   6.280   0.992   1.000 17.134 0 140  ILE A CA   1 ? 
ATOM   1923 C C    . ILE A 1 125 ? 4.606   5.529   -0.328  1.000 16.749 0 140  ILE A C    1 ? 
ATOM   1924 O O    . ILE A 1 125 ? 3.593   5.272   -1.003  1.000 17.304 0 140  ILE A O    1 ? 
ATOM   1925 C CB   . ILE A 1 125 ? 3.118   6.990   1.178   1.000 17.793 0 140  ILE A CB   1 ? 
ATOM   1926 C CG1  . ILE A 1 125 ? 2.867   8.095   0.149   1.000 17.231 0 140  ILE A CG1  1 ? 
ATOM   1927 C CG2  . ILE A 1 125 ? 3.009   7.477   2.637   1.000 20.792 0 140  ILE A CG2  1 ? 
ATOM   1928 C CD1  . ILE A 1 125 ? 1.438   8.617   0.095   1.000 19.715 0 140  ILE A CD1  1 ? 
ATOM   1929 H H    . ILE A 1 125 ? 5.706   7.897   0.628   1.000 16.946 0 140  ILE A H    1 c 
ATOM   1930 H HA   . ILE A 1 125 ? 4.523   5.609   1.695   1.000 17.134 0 140  ILE A HA   1 c 
ATOM   1931 H HB   . ILE A 1 125 ? 2.421   6.317   1.048   1.000 18.074 0 140  ILE A HB   1 c 
ATOM   1932 H HG12 . ILE A 1 125 ? 3.463   8.845   0.349   1.000 17.935 0 140  ILE A HG12 1 c 
ATOM   1933 H HG13 . ILE A 1 125 ? 3.106   7.758   -0.738  1.000 17.891 0 140  ILE A HG13 1 c 
ATOM   1934 H HG21 . ILE A 1 125 ? 2.126   7.852   2.791   1.000 19.853 0 140  ILE A HG21 1 c 
ATOM   1935 H HG22 . ILE A 1 125 ? 3.682   8.158   2.806   1.000 19.843 0 140  ILE A HG22 1 c 
ATOM   1936 H HG23 . ILE A 1 125 ? 3.150   6.729   3.242   1.000 19.843 0 140  ILE A HG23 1 c 
ATOM   1937 H HD11 . ILE A 1 125 ? 0.828   7.880   -0.099  1.000 18.950 0 140  ILE A HD11 1 c 
ATOM   1938 H HD12 . ILE A 1 125 ? 1.363   9.292   -0.605  1.000 18.949 0 140  ILE A HD12 1 c 
ATOM   1939 H HD13 . ILE A 1 125 ? 1.202   9.015   0.954   1.000 18.954 0 140  ILE A HD13 1 c 
ATOM   1940 N N    . GLN A 1 126 ? 5.861   5.265   -0.737  1.000 16.882 0 141  GLN A N    1 ? 
ATOM   1941 C CA   . GLN A 1 126 ? 6.129   4.646   -2.029  1.000 16.230 0 141  GLN A CA   1 ? 
ATOM   1942 C C    . GLN A 1 126 ? 6.297   3.129   -1.957  1.000 17.230 0 141  GLN A C    1 ? 
ATOM   1943 O O    . GLN A 1 126 ? 6.172   2.447   -2.991  1.000 16.676 0 141  GLN A O    1 ? 
ATOM   1944 C CB   . GLN A 1 126 ? 7.394   5.247   -2.643  1.000 16.659 0 141  GLN A CB   1 ? 
ATOM   1945 C CG   . GLN A 1 126 ? 8.716   4.855   -2.024  1.000 17.560 0 141  GLN A CG   1 ? 
ATOM   1946 C CD   . GLN A 1 126 ? 9.041   5.542   -0.710  1.000 18.120 0 141  GLN A CD   1 ? 
ATOM   1947 O OE1  . GLN A 1 126 ? 8.290   5.480   0.286   1.000 18.200 0 141  GLN A OE1  1 ? 
ATOM   1948 N NE2  . GLN A 1 126 ? 10.224  6.136   -0.698  1.000 18.809 0 141  GLN A NE2  1 ? 
ATOM   1949 H H    . GLN A 1 126 ? 6.563   5.463   -0.188  1.000 16.721 0 141  GLN A H    1 c 
ATOM   1950 H HA   . GLN A 1 126 ? 5.371   4.846   -2.635  1.000 16.619 0 141  GLN A HA   1 c 
ATOM   1951 H HB2  . GLN A 1 126 ? 7.414   4.999   -3.590  1.000 16.770 0 141  GLN A HB2  1 c 
ATOM   1952 H HB3  . GLN A 1 126 ? 7.313   6.223   -2.601  1.000 16.764 0 141  GLN A HB3  1 c 
ATOM   1953 H HG2  . GLN A 1 126 ? 8.726   3.887   -1.872  1.000 17.466 0 141  GLN A HG2  1 c 
ATOM   1954 H HG3  . GLN A 1 126 ? 9.433   5.056   -2.662  1.000 17.473 0 141  GLN A HG3  1 c 
ATOM   1955 H HE21 . GLN A 1 126 ? 10.920  5.755   -1.098  1.000 18.577 0 141  GLN A HE21 1 c 
ATOM   1956 H HE22 . GLN A 1 126 ? 10.321  6.917   -0.285  1.000 18.590 0 141  GLN A HE22 1 c 
ATOM   1957 N N    . SER A 1 127 ? 6.593   2.561   -0.761  1.000 15.877 0 142  SER A N    1 ? 
ATOM   1958 C CA   . SER A 1 127 ? 7.076   1.189   -0.619  1.000 16.125 0 142  SER A CA   1 ? 
ATOM   1959 C C    . SER A 1 127 ? 6.007   0.247   -0.102  1.000 15.877 0 142  SER A C    1 ? 
ATOM   1960 O O    . SER A 1 127 ? 5.005   0.683   0.443   1.000 15.354 0 142  SER A O    1 ? 
ATOM   1961 C CB   . SER A 1 127 ? 8.273   1.121   0.299   1.000 16.780 0 142  SER A CB   1 ? 
ATOM   1962 O OG   . SER A 1 127 ? 7.833   1.425   1.627   1.000 18.309 0 142  SER A OG   1 ? 
ATOM   1963 H H    . SER A 1 127 ? 6.485   3.059   -0.002  1.000 16.251 0 142  SER A H    1 c 
ATOM   1964 H HA   . SER A 1 127 ? 7.357   0.869   -1.513  1.000 16.163 0 142  SER A HA   1 c 
ATOM   1965 H HB2  . SER A 1 127 ? 8.660   0.225   0.274   1.000 16.973 0 142  SER A HB2  1 c 
ATOM   1966 H HB3  . SER A 1 127 ? 8.947   1.767   0.015   1.000 16.978 0 142  SER A HB3  1 c 
ATOM   1967 H HG   . SER A 1 127 ? 8.500   1.388   2.147   0.000 18.310 0 142  SER A HG   1 c 
ATOM   1968 N N    . LEU A 1 128 ? 6.274   -1.056  -0.193  1.000 15.606 0 143  LEU A N    1 ? 
ATOM   1969 C CA   . LEU A 1 128 ? 5.378   -2.059  0.364   1.000 16.336 0 143  LEU A CA   1 ? 
ATOM   1970 C C    . LEU A 1 128 ? 5.352   -1.984  1.899   1.000 16.493 0 143  LEU A C    1 ? 
ATOM   1971 O O    . LEU A 1 128 ? 4.350   -2.387  2.478   1.000 17.241 0 143  LEU A O    1 ? 
ATOM   1972 C CB   . LEU A 1 128 ? 5.690   -3.456  -0.130  1.000 17.258 0 143  LEU A CB   1 ? 
ATOM   1973 C CG   . LEU A 1 128 ? 5.482   -3.673  -1.628  1.000 19.021 0 143  LEU A CG   1 ? 
ATOM   1974 C CD1  . LEU A 1 128 ? 5.748   -5.102  -2.015  1.000 19.704 0 143  LEU A CD1  1 ? 
ATOM   1975 C CD2  . LEU A 1 128 ? 4.086   -3.211  -2.071  1.000 19.747 0 143  LEU A CD2  1 ? 
ATOM   1976 H H    . LEU A 1 128 ? 7.037   -1.331  -0.615  1.000 15.850 0 143  LEU A H    1 c 
ATOM   1977 H HA   . LEU A 1 128 ? 4.465   -1.827  0.060   1.000 16.414 0 143  LEU A HA   1 c 
ATOM   1978 H HB2  . LEU A 1 128 ? 6.630   -3.658  0.088   1.000 17.421 0 143  LEU A HB2  1 c 
ATOM   1979 H HB3  . LEU A 1 128 ? 5.120   -4.092  0.360   1.000 17.417 0 143  LEU A HB3  1 c 
ATOM   1980 H HG   . LEU A 1 128 ? 6.143   -3.110  -2.108  1.000 18.937 0 143  LEU A HG   1 c 
ATOM   1981 H HD11 . LEU A 1 128 ? 6.638   -5.354  -1.723  1.000 19.478 0 143  LEU A HD11 1 c 
ATOM   1982 H HD12 . LEU A 1 128 ? 5.685   -5.194  -2.981  1.000 19.493 0 143  LEU A HD12 1 c 
ATOM   1983 H HD13 . LEU A 1 128 ? 5.092   -5.681  -1.592  1.000 19.493 0 143  LEU A HD13 1 c 
ATOM   1984 H HD21 . LEU A 1 128 ? 4.071   -2.242  -2.146  1.000 19.489 0 143  LEU A HD21 1 c 
ATOM   1985 H HD22 . LEU A 1 128 ? 3.426   -3.495  -1.415  1.000 19.522 0 143  LEU A HD22 1 c 
ATOM   1986 H HD23 . LEU A 1 128 ? 3.872   -3.605  -2.934  1.000 19.523 0 143  LEU A HD23 1 c 
ATOM   1987 N N    . PHE A 1 129 ? 6.388   -1.406  2.535   1.000 16.707 0 144  PHE A N    1 ? 
ATOM   1988 C CA   . PHE A 1 129 ? 6.353   -1.139  3.969   1.000 17.105 0 144  PHE A CA   1 ? 
ATOM   1989 C C    . PHE A 1 129 ? 5.210   -0.182  4.274   1.000 17.812 0 144  PHE A C    1 ? 
ATOM   1990 O O    . PHE A 1 129 ? 4.439   -0.415  5.211   1.000 18.159 0 144  PHE A O    1 ? 
ATOM   1991 C CB   . PHE A 1 129 ? 7.717   -0.669  4.465   1.000 17.813 0 144  PHE A CB   1 ? 
ATOM   1992 C CG   . PHE A 1 129 ? 7.758   -0.413  5.973   1.000 16.872 0 144  PHE A CG   1 ? 
ATOM   1993 C CD1  . PHE A 1 129 ? 7.390   0.815   6.493   1.000 18.293 0 144  PHE A CD1  1 ? 
ATOM   1994 C CD2  . PHE A 1 129 ? 8.172   -1.427  6.791   1.000 18.247 0 144  PHE A CD2  1 ? 
ATOM   1995 C CE1  . PHE A 1 129 ? 7.413   1.014   7.872   1.000 19.919 0 144  PHE A CE1  1 ? 
ATOM   1996 C CE2  . PHE A 1 129 ? 8.211   -1.226  8.166   1.000 18.833 0 144  PHE A CE2  1 ? 
ATOM   1997 C CZ   . PHE A 1 129 ? 7.858   -0.003  8.688   1.000 19.298 0 144  PHE A CZ   1 ? 
ATOM   1998 H H    . PHE A 1 129 ? 7.140   -1.185  2.066   1.000 16.738 0 144  PHE A H    1 c 
ATOM   1999 H HA   . PHE A 1 129 ? 6.152   -1.998  4.426   1.000 17.288 0 144  PHE A HA   1 c 
ATOM   2000 H HB2  . PHE A 1 129 ? 8.388   -1.349  4.234   1.000 17.442 0 144  PHE A HB2  1 c 
ATOM   2001 H HB3  . PHE A 1 129 ? 7.948   0.162   3.996   1.000 17.434 0 144  PHE A HB3  1 c 
ATOM   2002 H HD1  . PHE A 1 129 ? 7.098   1.504   5.918   1.000 18.321 0 144  PHE A HD1  1 c 
ATOM   2003 H HD2  . PHE A 1 129 ? 8.425   -2.259  6.424   1.000 18.062 0 144  PHE A HD2  1 c 
ATOM   2004 H HE1  . PHE A 1 129 ? 7.174   1.851   8.237   1.000 19.356 0 144  PHE A HE1  1 c 
ATOM   2005 H HE2  . PHE A 1 129 ? 8.502   -1.919  8.737   1.000 18.794 0 144  PHE A HE2  1 c 
ATOM   2006 H HZ   . PHE A 1 129 ? 7.879   0.127   9.622   1.000 19.301 0 144  PHE A HZ   1 c 
ATOM   2007 N N    . SER A 1 130 ? 5.056   0.897   3.480   1.000 15.845 0 145  SER A N    1 ? 
ATOM   2008 C CA   . SER A 1 130 ? 3.989   1.859   3.678   1.000 16.520 0 145  SER A CA   1 ? 
ATOM   2009 C C    . SER A 1 130 ? 2.629   1.190   3.414   1.000 18.124 0 145  SER A C    1 ? 
ATOM   2010 O O    . SER A 1 130 ? 1.657   1.421   4.142   1.000 17.652 0 145  SER A O    1 ? 
ATOM   2011 C CB   . SER A 1 130 ? 4.163   3.077   2.800   1.000 18.803 0 145  SER A CB   1 ? 
ATOM   2012 O OG   . SER A 1 130 ? 3.078   3.998   2.905   1.000 19.223 0 145  SER A OG   1 ? 
ATOM   2013 H H    . SER A 1 130 ? 5.645   1.032   2.795   1.000 16.468 0 145  SER A H    1 c 
ATOM   2014 H HA   . SER A 1 130 ? 4.011   2.152   4.625   1.000 17.077 0 145  SER A HA   1 c 
ATOM   2015 H HB2  . SER A 1 130 ? 4.992   3.530   3.047   1.000 18.351 0 145  SER A HB2  1 c 
ATOM   2016 H HB3  . SER A 1 130 ? 4.248   2.789   1.871   1.000 18.338 0 145  SER A HB3  1 c 
ATOM   2017 H HG   . SER A 1 130 ? 3.229   4.655   2.391   0.000 19.200 0 145  SER A HG   1 c 
ATOM   2018 N N    . PHE A 1 131 ? 2.549   0.352   2.380   1.000 16.696 0 146  PHE A N    1 ? 
ATOM   2019 C CA   . PHE A 1 131 ? 1.295   -0.326  2.082   1.000 16.763 0 146  PHE A CA   1 ? 
ATOM   2020 C C    . PHE A 1 131 ? 0.824   -1.179  3.250   1.000 17.304 0 146  PHE A C    1 ? 
ATOM   2021 O O    . PHE A 1 131 ? -0.366  -1.145  3.586   1.000 20.120 0 146  PHE A O    1 ? 
ATOM   2022 C CB   . PHE A 1 131 ? 1.476   -1.184  0.828   1.000 17.030 0 146  PHE A CB   1 ? 
ATOM   2023 C CG   . PHE A 1 131 ? 0.258   -1.987  0.419   1.000 17.398 0 146  PHE A CG   1 ? 
ATOM   2024 C CD1  . PHE A 1 131 ? -0.848  -1.350  -0.117  1.000 18.712 0 146  PHE A CD1  1 ? 
ATOM   2025 C CD2  . PHE A 1 131 ? 0.226   -3.360  0.599   1.000 19.285 0 146  PHE A CD2  1 ? 
ATOM   2026 C CE1  . PHE A 1 131 ? -1.969  -2.093  -0.512  1.000 19.614 0 146  PHE A CE1  1 ? 
ATOM   2027 C CE2  . PHE A 1 131 ? -0.875  -4.107  0.176   1.000 20.785 0 146  PHE A CE2  1 ? 
ATOM   2028 C CZ   . PHE A 1 131 ? -1.996  -3.453  -0.345  1.000 20.366 0 146  PHE A CZ   1 ? 
ATOM   2029 H H    . PHE A 1 131 ? 3.277   0.203   1.848   1.000 17.030 0 146  PHE A H    1 c 
ATOM   2030 H HA   . PHE A 1 131 ? 0.604   0.364   1.894   1.000 16.917 0 146  PHE A HA   1 c 
ATOM   2031 H HB2  . PHE A 1 131 ? 1.729   -0.594  0.083   1.000 17.055 0 146  PHE A HB2  1 c 
ATOM   2032 H HB3  . PHE A 1 131 ? 2.225   -1.802  0.982   1.000 17.078 0 146  PHE A HB3  1 c 
ATOM   2033 H HD1  . PHE A 1 131 ? -0.838  -0.413  -0.233  1.000 18.618 0 146  PHE A HD1  1 c 
ATOM   2034 H HD2  . PHE A 1 131 ? 0.984   -3.801  0.948   1.000 19.140 0 146  PHE A HD2  1 c 
ATOM   2035 H HE1  . PHE A 1 131 ? -2.718  -1.650  -0.878  1.000 19.585 0 146  PHE A HE1  1 c 
ATOM   2036 H HE2  . PHE A 1 131 ? -0.890  -5.042  0.307   1.000 20.289 0 146  PHE A HE2  1 c 
ATOM   2037 H HZ   . PHE A 1 131 ? -2.753  -3.949  -0.613  1.000 20.242 0 146  PHE A HZ   1 c 
ATOM   2038 N N    . ILE A 1 132 ? 1.753   -1.942  3.841   1.000 16.346 0 147  ILE A N    1 ? 
ATOM   2039 C CA   . ILE A 1 132 ? 1.400   -2.886  4.891   1.000 18.295 0 147  ILE A CA   1 ? 
ATOM   2040 C C    . ILE A 1 132 ? 1.163   -2.169  6.228   1.000 20.013 0 147  ILE A C    1 ? 
ATOM   2041 O O    . ILE A 1 132 ? 0.166   -2.467  6.894   1.000 22.311 0 147  ILE A O    1 ? 
ATOM   2042 C CB   . ILE A 1 132 ? 2.450   -3.984  5.043   1.000 20.680 0 147  ILE A CB   1 ? 
ATOM   2043 C CG1  . ILE A 1 132 ? 2.444   -4.935  3.849   1.000 19.766 0 147  ILE A CG1  1 ? 
ATOM   2044 C CG2  . ILE A 1 132 ? 2.200   -4.753  6.345   1.000 23.995 0 147  ILE A CG2  1 ? 
ATOM   2045 C CD1  . ILE A 1 132 ? 1.138   -5.685  3.672   1.000 24.142 0 147  ILE A CD1  1 ? 
ATOM   2046 H H    . ILE A 1 132 ? 2.627   -1.876  3.582   1.000 17.037 0 147  ILE A H    1 c 
ATOM   2047 H HA   . ILE A 1 132 ? 0.561   -3.312  4.634   1.000 18.689 0 147  ILE A HA   1 c 
ATOM   2048 H HB   . ILE A 1 132 ? 3.331   -3.562  5.096   1.000 20.579 0 147  ILE A HB   1 c 
ATOM   2049 H HG12 . ILE A 1 132 ? 2.625   -4.420  3.036   1.000 20.884 0 147  ILE A HG12 1 c 
ATOM   2050 H HG13 . ILE A 1 132 ? 3.168   -5.585  3.960   1.000 20.904 0 147  ILE A HG13 1 c 
ATOM   2051 H HG21 . ILE A 1 132 ? 2.665   -5.606  6.312   1.000 22.936 0 147  ILE A HG21 1 c 
ATOM   2052 H HG22 . ILE A 1 132 ? 1.247   -4.910  6.456   1.000 22.918 0 147  ILE A HG22 1 c 
ATOM   2053 H HG23 . ILE A 1 132 ? 2.533   -4.238  7.100   1.000 22.939 0 147  ILE A HG23 1 c 
ATOM   2054 H HD11 . ILE A 1 132 ? 0.918   -6.172  4.488   1.000 22.749 0 147  ILE A HD11 1 c 
ATOM   2055 H HD12 . ILE A 1 132 ? 1.236   -6.318  2.937   1.000 22.731 0 147  ILE A HD12 1 c 
ATOM   2056 H HD13 . ILE A 1 132 ? 0.417   -5.061  3.464   1.000 22.695 0 147  ILE A HD13 1 c 
ATOM   2057 N N    . THR A 1 133 ? 2.039   -1.240  6.609   1.000 18.448 0 148  THR A N    1 ? 
ATOM   2058 C CA   . THR A 1 133 ? 1.950   -0.659  7.952   1.000 19.756 0 148  THR A CA   1 ? 
ATOM   2059 C C    . THR A 1 133 ? 1.004   0.534   7.998   1.000 23.098 0 148  THR A C    1 ? 
ATOM   2060 O O    . THR A 1 133 ? 0.446   0.862   9.059   1.000 21.254 0 148  THR A O    1 ? 
ATOM   2061 C CB   . THR A 1 133 ? 3.338   -0.305  8.484   1.000 18.800 0 148  THR A CB   1 ? 
ATOM   2062 O OG1  . THR A 1 133 ? 3.839   0.769   7.687   1.000 19.838 0 148  THR A OG1  1 ? 
ATOM   2063 C CG2  . THR A 1 133 ? 4.266   -1.497  8.535   1.000 18.764 0 148  THR A CG2  1 ? 
ATOM   2064 H H    . THR A 1 133 ? 2.699   -0.962  6.042   1.000 19.075 0 148  THR A H    1 c 
ATOM   2065 H HA   . THR A 1 133 ? 1.582   -1.349  8.544   1.000 19.901 0 148  THR A HA   1 c 
ATOM   2066 H HB   . THR A 1 133 ? 3.234   0.019   9.411   1.000 19.163 0 148  THR A HB   1 c 
ATOM   2067 H HG1  . THR A 1 133 ? 3.885   0.520   6.864   0.000 19.830 0 148  THR A HG1  1 c 
ATOM   2068 H HG21 . THR A 1 133 ? 5.112   -1.232  8.934   1.000 18.775 0 148  THR A HG21 1 c 
ATOM   2069 H HG22 . THR A 1 133 ? 4.423   -1.827  7.635   1.000 18.773 0 148  THR A HG22 1 c 
ATOM   2070 H HG23 . THR A 1 133 ? 3.862   -2.200  9.071   1.000 18.775 0 148  THR A HG23 1 c 
ATOM   2071 N N    . GLY A 1 134 ? 0.814   1.215   6.868   1.000 20.093 0 149  GLY A N    1 ? 
ATOM   2072 C CA   . GLY A 1 134 ? 0.096   2.484   6.826   1.000 20.184 0 149  GLY A CA   1 ? 
ATOM   2073 C C    . GLY A 1 134 ? -1.119  2.450   5.907   1.000 19.644 0 149  GLY A C    1 ? 
ATOM   2074 O O    . GLY A 1 134 ? -1.844  3.417   5.865   1.000 22.113 0 149  GLY A O    1 ? 
ATOM   2075 H H    . GLY A 1 134 ? 1.164   0.889   6.090   1.000 20.770 0 149  GLY A H    1 c 
ATOM   2076 H HA2  . GLY A 1 134 ? -0.195  2.722   7.737   1.000 20.064 0 149  GLY A HA2  1 c 
ATOM   2077 H HA3  . GLY A 1 134 ? 0.714   3.187   6.518   1.000 20.045 0 149  GLY A HA3  1 c 
ATOM   2078 N N    . THR A 1 135 ? -1.320  1.363   5.156   1.000 21.141 0 150  THR A N    1 ? 
ATOM   2079 C CA   . THR A 1 135 ? -2.354  1.273   4.113   1.000 21.116 0 150  THR A CA   1 ? 
ATOM   2080 C C    . THR A 1 135 ? -2.385  2.524   3.219   1.000 20.886 0 150  THR A C    1 ? 
ATOM   2081 O O    . THR A 1 135 ? -3.430  2.981   2.778   1.000 21.629 0 150  THR A O    1 ? 
ATOM   2082 C CB   . THR A 1 135 ? -3.707  0.829   4.703   1.000 21.753 0 150  THR A CB   1 ? 
ATOM   2083 O OG1  . THR A 1 135 ? -4.238  1.846   5.543   1.000 25.680 0 150  THR A OG1  1 ? 
ATOM   2084 C CG2  . THR A 1 135 ? -3.560  -0.506  5.405   1.000 24.825 0 150  THR A CG2  1 ? 
ATOM   2085 H H    . THR A 1 135 ? -0.795  0.629   5.299   1.000 20.759 0 150  THR A H    1 c 
ATOM   2086 H HA   . THR A 1 135 ? -2.073  0.539   3.528   1.000 21.204 0 150  THR A HA   1 c 
ATOM   2087 H HB   . THR A 1 135 ? -4.332  0.693   3.952   1.000 22.914 0 150  THR A HB   1 c 
ATOM   2088 H HG1  . THR A 1 135 ? -3.693  2.001   6.191   0.000 25.580 0 150  THR A HG1  1 c 
ATOM   2089 H HG21 . THR A 1 135 ? -4.433  -0.813  5.703   1.000 23.864 0 150  THR A HG21 1 c 
ATOM   2090 H HG22 . THR A 1 135 ? -2.973  -0.408  6.173   1.000 23.852 0 150  THR A HG22 1 c 
ATOM   2091 H HG23 . THR A 1 135 ? -3.182  -1.157  4.790   1.000 23.849 0 150  THR A HG23 1 c 
ATOM   2092 N N    . LYS A 1 136 ? -1.196  3.025   2.845   1.000 18.837 0 151  LYS A N    1 ? 
ATOM   2093 C CA   . LYS A 1 136 ? -1.033  4.219   2.035   1.000 21.806 0 151  LYS A CA   1 ? 
ATOM   2094 C C    . LYS A 1 136 ? 0.023   3.976   0.952   1.000 19.014 0 151  LYS A C    1 ? 
ATOM   2095 O O    . LYS A 1 136 ? 1.100   3.463   1.237   1.000 17.850 0 151  LYS A O    1 ? 
ATOM   2096 C CB   . LYS A 1 136 ? -0.568  5.407   2.894   1.000 24.947 0 151  LYS A CB   1 ? 
ATOM   2097 C CG   . LYS A 1 136 ? -1.681  5.964   3.767   1.000 28.656 0 151  LYS A CG   1 ? 
ATOM   2098 C CD   . LYS A 1 136 ? -1.202  6.975   4.812   1.000 33.622 0 151  LYS A CD   1 ? 
ATOM   2099 C CE   . LYS A 1 136 ? -1.159  6.410   6.230   1.000 37.494 0 151  LYS A CE   1 ? 
ATOM   2100 N NZ   . LYS A 1 136 ? 0.107   6.708   6.923   1.000 44.479 0 151  LYS A NZ   1 ? 
ATOM   2101 H H    . LYS A 1 136 ? -0.441  2.584   3.109   1.000 19.966 0 151  LYS A H    1 c 
ATOM   2102 H HA   . LYS A 1 136 ? -1.898  4.437   1.605   1.000 21.122 0 151  LYS A HA   1 c 
ATOM   2103 H HB2  . LYS A 1 136 ? 0.173   5.119   3.469   1.000 24.978 0 151  LYS A HB2  1 c 
ATOM   2104 H HB3  . LYS A 1 136 ? -0.238  6.121   2.308   1.000 24.947 0 151  LYS A HB3  1 c 
ATOM   2105 H HG2  . LYS A 1 136 ? -2.342  6.397   3.187   1.000 28.785 0 151  LYS A HG2  1 c 
ATOM   2106 H HG3  . LYS A 1 136 ? -2.128  5.218   4.220   1.000 28.798 0 151  LYS A HG3  1 c 
ATOM   2107 H HD2  . LYS A 1 136 ? -0.304  7.286   4.565   1.000 33.292 0 151  LYS A HD2  1 c 
ATOM   2108 H HD3  . LYS A 1 136 ? -1.802  7.752   4.798   1.000 33.247 0 151  LYS A HD3  1 c 
ATOM   2109 H HE2  . LYS A 1 136 ? -1.894  6.785   6.746   1.000 38.042 0 151  LYS A HE2  1 c 
ATOM   2110 H HE3  . LYS A 1 136 ? -1.274  5.446   6.206   1.000 37.800 0 151  LYS A HE3  1 c 
ATOM   2111 H HZ1  . LYS A 1 136 ? 0.305   7.588   6.835   1.000 42.076 0 151  LYS A HZ1  1 c 
ATOM   2112 H HZ2  . LYS A 1 136 ? 0.776   6.214   6.564   1.000 42.170 0 151  LYS A HZ2  1 c 
ATOM   2113 H HZ3  . LYS A 1 136 ? 0.026   6.508   7.802   1.000 42.170 0 151  LYS A HZ3  1 c 
ATOM   2114 N N    . LEU A 1 137 ? -0.302  4.377   -0.283  1.000 16.979 0 152  LEU A N    1 ? 
ATOM   2115 C CA   . LEU A 1 137 ? 0.633   4.386   -1.395  1.000 17.167 0 152  LEU A CA   1 ? 
ATOM   2116 C C    . LEU A 1 137 ? 0.428   5.648   -2.229  1.000 16.663 0 152  LEU A C    1 ? 
ATOM   2117 O O    . LEU A 1 137 ? -0.709  6.127   -2.413  1.000 17.902 0 152  LEU A O    1 ? 
ATOM   2118 C CB   . LEU A 1 137 ? 0.493   3.151   -2.300  1.000 16.765 0 152  LEU A CB   1 ? 
ATOM   2119 C CG   . LEU A 1 137 ? 0.999   1.805   -1.737  1.000 16.475 0 152  LEU A CG   1 ? 
ATOM   2120 C CD1  . LEU A 1 137 ? 0.680   0.658   -2.677  1.000 18.179 0 152  LEU A CD1  1 ? 
ATOM   2121 C CD2  . LEU A 1 137 ? 2.508   1.866   -1.561  1.000 16.616 0 152  LEU A CD2  1 ? 
ATOM   2122 H H    . LEU A 1 137 ? -1.158  4.657   -0.439  1.000 17.537 0 152  LEU A H    1 c 
ATOM   2123 H HA   . LEU A 1 137 ? 1.545   4.408   -1.024  1.000 16.959 0 152  LEU A HA   1 c 
ATOM   2124 H HB2  . LEU A 1 137 ? -0.459  3.049   -2.532  1.000 16.789 0 152  LEU A HB2  1 c 
ATOM   2125 H HB3  . LEU A 1 137 ? 0.975   3.332   -3.140  1.000 16.787 0 152  LEU A HB3  1 c 
ATOM   2126 H HG   . LEU A 1 137 ? 0.571   1.640   -0.857  1.000 16.859 0 152  LEU A HG   1 c 
ATOM   2127 H HD11 . LEU A 1 137 ? -0.282  0.601   -2.805  1.000 17.649 0 152  LEU A HD11 1 c 
ATOM   2128 H HD12 . LEU A 1 137 ? 1.004   -0.175  -2.295  1.000 17.643 0 152  LEU A HD12 1 c 
ATOM   2129 H HD13 . LEU A 1 137 ? 1.112   0.811   -3.534  1.000 17.627 0 152  LEU A HD13 1 c 
ATOM   2130 H HD21 . LEU A 1 137 ? 2.728   2.487   -0.847  1.000 16.585 0 152  LEU A HD21 1 c 
ATOM   2131 H HD22 . LEU A 1 137 ? 2.920   2.164   -2.389  1.000 16.582 0 152  LEU A HD22 1 c 
ATOM   2132 H HD23 . LEU A 1 137 ? 2.844   0.982   -1.333  1.000 16.595 0 152  LEU A HD23 1 c 
ATOM   2133 N N    . ASP A 1 138 ? 1.511   6.152   -2.810  1.000 15.332 0 153  ASP A N    1 ? 
ATOM   2134 C CA   . ASP A 1 138 ? 1.468   7.188   -3.828  1.000 16.267 0 153  ASP A CA   1 ? 
ATOM   2135 C C    . ASP A 1 138 ? 1.124   6.573   -5.183  1.000 16.702 0 153  ASP A C    1 ? 
ATOM   2136 O O    . ASP A 1 138 ? 1.001   5.341   -5.299  1.000 17.629 0 153  ASP A O    1 ? 
ATOM   2137 C CB   . ASP A 1 138 ? 2.713   8.068   -3.792  1.000 16.230 0 153  ASP A CB   1 ? 
ATOM   2138 C CG   . ASP A 1 138 ? 4.033   7.382   -4.102  1.000 18.236 0 153  ASP A CG   1 ? 
ATOM   2139 O OD1  . ASP A 1 138 ? 4.022   6.303   -4.719  1.000 18.224 0 153  ASP A OD1  1 ? 
ATOM   2140 O OD2  . ASP A 1 138 ? 5.102   7.905   -3.657  1.000 19.564 0 153  ASP A OD2  1 ? 
ATOM   2141 H H    . ASP A 1 138 ? 2.328   5.830   -2.558  1.000 15.883 0 153  ASP A H    1 c 
ATOM   2142 H HA   . ASP A 1 138 ? 0.734   7.799   -3.593  1.000 16.166 0 153  ASP A HA   1 c 
ATOM   2143 H HB2  . ASP A 1 138 ? 2.601   8.801   -4.431  1.000 16.738 0 153  ASP A HB2  1 c 
ATOM   2144 H HB3  . ASP A 1 138 ? 2.784   8.464   -2.899  1.000 16.700 0 153  ASP A HB3  1 c 
ATOM   2145 N N    A SER A 1 139 ? 0.916   7.421   -6.206  0.500 18.958 0 154  SER A N    1 ? 
ATOM   2146 N N    B SER A 1 139 ? 0.870   7.435   -6.180  0.500 16.882 0 154  SER A N    1 ? 
ATOM   2147 C CA   A SER A 1 139 ? 0.372   6.967   -7.483  0.500 18.894 0 154  SER A CA   1 ? 
ATOM   2148 C CA   B SER A 1 139 ? 0.396   6.982   -7.482  0.500 15.570 0 154  SER A CA   1 ? 
ATOM   2149 C C    A SER A 1 139 ? 1.219   5.869   -8.134  0.500 17.156 0 154  SER A C    1 ? 
ATOM   2150 C C    B SER A 1 139 ? 1.235   5.835   -8.047  0.500 15.526 0 154  SER A C    1 ? 
ATOM   2151 O O    A SER A 1 139 ? 0.707   4.832   -8.568  0.500 16.428 0 154  SER A O    1 ? 
ATOM   2152 O O    B SER A 1 139 ? 0.737   4.736   -8.325  0.500 15.718 0 154  SER A O    1 ? 
ATOM   2153 C CB   A SER A 1 139 ? 0.162   8.145   -8.428  0.500 21.474 0 154  SER A CB   1 ? 
ATOM   2154 C CB   B SER A 1 139 ? 0.364   8.142   -8.448  0.500 15.286 0 154  SER A CB   1 ? 
ATOM   2155 O OG   A SER A 1 139 ? 1.346   8.899   -8.646  0.500 23.307 0 154  SER A OG   1 ? 
ATOM   2156 O OG   B SER A 1 139 ? 0.007   7.675   -9.742  0.500 14.010 0 154  SER A OG   1 ? 
ATOM   2157 H H    A SER A 1 139 ? 1.116   8.307   -6.104  0.500 18.338 0 154  SER A H    1 c 
ATOM   2158 H H    B SER A 1 139 ? 0.993   8.330   -6.043  0.500 16.533 0 154  SER A H    1 c 
ATOM   2159 H HA   A SER A 1 139 ? -0.519  6.575   -7.296  0.500 19.018 0 154  SER A HA   1 c 
ATOM   2160 H HA   B SER A 1 139 ? -0.531  6.651   -7.367  0.500 15.755 0 154  SER A HA   1 c 
ATOM   2161 H HB2  A SER A 1 139 ? -0.166  7.811   -9.285  0.500 21.282 0 154  SER A HB2  1 c 
ATOM   2162 H HB2  B SER A 1 139 ? -0.288  8.802   -8.145  0.500 15.035 0 154  SER A HB2  1 c 
ATOM   2163 H HB3  A SER A 1 139 ? -0.523  8.731   -8.058  0.500 21.307 0 154  SER A HB3  1 c 
ATOM   2164 H HB3  B SER A 1 139 ? 1.243   8.565   -8.481  0.500 15.040 0 154  SER A HB3  1 c 
ATOM   2165 H HG   A SER A 1 139 ? 1.168   9.537   -9.173  0.000 23.220 0 154  SER A HG   1 c 
ATOM   2166 H HG   B SER A 1 139 ? -0.009  8.329   -10.272 0.000 14.000 0 154  SER A HG   1 c 
ATOM   2167 N N    . SER A 1 140 ? 2.528   6.119   -8.268  1.000 15.862 0 155  SER A N    1 ? 
ATOM   2168 C CA   . SER A 1 140 ? 3.392   5.126   -8.876  1.000 15.637 0 155  SER A CA   1 ? 
ATOM   2169 C C    . SER A 1 140 ? 3.671   3.959   -7.926  1.000 15.160 0 155  SER A C    1 ? 
ATOM   2170 O O    . SER A 1 140 ? 3.921   2.834   -8.376  1.000 15.418 0 155  SER A O    1 ? 
ATOM   2171 C CB   . SER A 1 140 ? 4.630   5.728   -9.455  1.000 17.228 0 155  SER A CB   1 ? 
ATOM   2172 O OG   . SER A 1 140 ? 5.432   6.368   -8.461  1.000 17.693 0 155  SER A OG   1 ? 
ATOM   2173 H H    . SER A 1 140 ? 2.872   6.924   -8.006  1.000 16.018 0 155  SER A H    1 c 
ATOM   2174 H HA   . SER A 1 140 ? 2.889   4.745   -9.641  1.000 15.889 0 155  SER A HA   1 c 
ATOM   2175 H HB2  . SER A 1 140 ? 5.154   5.027   -9.888  1.000 16.956 0 155  SER A HB2  1 c 
ATOM   2176 H HB3  . SER A 1 140 ? 4.380   6.381   -10.136 1.000 16.956 0 155  SER A HB3  1 c 
ATOM   2177 H HG   . SER A 1 140 ? 6.116   6.691   -8.835  0.000 17.700 0 155  SER A HG   1 c 
ATOM   2178 N N    . GLY A 1 141 ? 3.531   4.197   -6.614  1.000 14.834 0 156  GLY A N    1 ? 
ATOM   2179 C CA   . GLY A 1 141 ? 3.627   3.136   -5.623  1.000 16.061 0 156  GLY A CA   1 ? 
ATOM   2180 C C    . GLY A 1 141 ? 2.552   2.054   -5.818  1.000 15.114 0 156  GLY A C    1 ? 
ATOM   2181 O O    . GLY A 1 141 ? 2.817   0.867   -5.639  1.000 15.007 0 156  GLY A O    1 ? 
ATOM   2182 H H    . GLY A 1 141 ? 3.385   5.052   -6.326  1.000 15.200 0 156  GLY A H    1 c 
ATOM   2183 H HA2  . GLY A 1 141 ? 4.519   2.724   -5.682  1.000 15.558 0 156  GLY A HA2  1 c 
ATOM   2184 H HA3  . GLY A 1 141 ? 3.535   3.530   -4.724  1.000 15.550 0 156  GLY A HA3  1 c 
ATOM   2185 N N    . VAL A 1 142 ? 1.354   2.456   -6.216  1.000 15.365 0 157  VAL A N    1 ? 
ATOM   2186 C CA   . VAL A 1 142 ? 0.316   1.475   -6.531  1.000 15.275 0 157  VAL A CA   1 ? 
ATOM   2187 C C    . VAL A 1 142 ? 0.711   0.600   -7.726  1.000 16.623 0 157  VAL A C    1 ? 
ATOM   2188 O O    . VAL A 1 142 ? 0.572   -0.614  -7.710  1.000 17.066 0 157  VAL A O    1 ? 
ATOM   2189 C CB   . VAL A 1 142 ? -1.038  2.178   -6.794  1.000 16.473 0 157  VAL A CB   1 ? 
ATOM   2190 C CG1  . VAL A 1 142 ? -2.084  1.237   -7.371  1.000 17.249 0 157  VAL A CG1  1 ? 
ATOM   2191 C CG2  . VAL A 1 142 ? -1.565  2.869   -5.544  1.000 17.954 0 157  VAL A CG2  1 ? 
ATOM   2192 H H    . VAL A 1 142 ? 1.167   3.348   -6.293  1.000 15.332 0 157  VAL A H    1 c 
ATOM   2193 H HA   . VAL A 1 142 ? 0.207   0.894   -5.754  1.000 15.752 0 157  VAL A HA   1 c 
ATOM   2194 H HB   . VAL A 1 142 ? -0.871  2.876   -7.466  1.000 16.642 0 157  VAL A HB   1 c 
ATOM   2195 H HG11 . VAL A 1 142 ? -2.095  0.411   -6.859  1.000 17.018 0 157  VAL A HG11 1 c 
ATOM   2196 H HG12 . VAL A 1 142 ? -1.871  1.041   -8.299  1.000 17.017 0 157  VAL A HG12 1 c 
ATOM   2197 H HG13 . VAL A 1 142 ? -2.960  1.657   -7.325  1.000 17.025 0 157  VAL A HG13 1 c 
ATOM   2198 H HG21 . VAL A 1 142 ? -2.451  3.227   -5.719  1.000 17.540 0 157  VAL A HG21 1 c 
ATOM   2199 H HG22 . VAL A 1 142 ? -0.967  3.594   -5.296  1.000 17.487 0 157  VAL A HG22 1 c 
ATOM   2200 H HG23 . VAL A 1 142 ? -1.615  2.229   -4.814  1.000 17.508 0 157  VAL A HG23 1 c 
ATOM   2201 N N    . ALA A 1 143 ? 1.198   1.217   -8.793  1.000 15.637 0 158  ALA A N    1 ? 
ATOM   2202 C CA   . ALA A 1 143 ? 1.650   0.428   -9.933  1.000 14.854 0 158  ALA A CA   1 ? 
ATOM   2203 C C    . ALA A 1 143 ? 2.761   -0.549  -9.557  1.000 15.349 0 158  ALA A C    1 ? 
ATOM   2204 O O    . ALA A 1 143 ? 2.737   -1.701  -9.981  1.000 15.862 0 158  ALA A O    1 ? 
ATOM   2205 C CB   . ALA A 1 143 ? 2.111   1.326   -11.057 1.000 14.810 0 158  ALA A CB   1 ? 
ATOM   2206 H H    . ALA A 1 143 ? 1.249   2.129   -8.823  1.000 15.676 0 158  ALA A H    1 c 
ATOM   2207 H HA   . ALA A 1 143 ? 0.874   -0.108  -10.257 1.000 15.107 0 158  ALA A HA   1 c 
ATOM   2208 H HB1  . ALA A 1 143 ? 1.378   1.898   -11.341 1.000 14.824 0 158  ALA A HB1  1 c 
ATOM   2209 H HB2  . ALA A 1 143 ? 2.850   1.879   -10.752 1.000 14.824 0 158  ALA A HB2  1 c 
ATOM   2210 H HB3  . ALA A 1 143 ? 2.405   0.785   -11.809 1.000 14.826 0 158  ALA A HB3  1 c 
ATOM   2211 N N    . PHE A 1 144 ? 3.736   -0.100  -8.757  1.000 14.913 0 159  PHE A N    1 ? 
ATOM   2212 C CA   . PHE A 1 144 ? 4.781   -1.008  -8.306  1.000 14.672 0 159  PHE A CA   1 ? 
ATOM   2213 C C    . PHE A 1 144 ? 4.203   -2.168  -7.494  1.000 14.684 0 159  PHE A C    1 ? 
ATOM   2214 O O    . PHE A 1 144 ? 4.613   -3.307  -7.670  1.000 15.539 0 159  PHE A O    1 ? 
ATOM   2215 C CB   . PHE A 1 144 ? 5.800   -0.188  -7.507  1.000 14.876 0 159  PHE A CB   1 ? 
ATOM   2216 C CG   . PHE A 1 144 ? 6.893   -1.094  -6.971  1.000 16.049 0 159  PHE A CG   1 ? 
ATOM   2217 C CD1  . PHE A 1 144 ? 7.986   -1.432  -7.739  1.000 16.567 0 159  PHE A CD1  1 ? 
ATOM   2218 C CD2  . PHE A 1 144 ? 6.778   -1.658  -5.705  1.000 18.231 0 159  PHE A CD2  1 ? 
ATOM   2219 C CE1  . PHE A 1 144 ? 8.965   -2.296  -7.238  1.000 17.523 0 159  PHE A CE1  1 ? 
ATOM   2220 C CE2  . PHE A 1 144 ? 7.736   -2.507  -5.211  1.000 18.416 0 159  PHE A CE2  1 ? 
ATOM   2221 C CZ   . PHE A 1 144 ? 8.817   -2.853  -5.985  1.000 19.416 0 159  PHE A CZ   1 ? 
ATOM   2222 H H    . PHE A 1 144 ? 3.754   0.775   -8.495  1.000 14.964 0 159  PHE A H    1 c 
ATOM   2223 H HA   . PHE A 1 144 ? 5.238   -1.381  -9.107  1.000 14.763 0 159  PHE A HA   1 c 
ATOM   2224 H HB2  . PHE A 1 144 ? 6.197   0.494   -8.093  1.000 15.088 0 159  PHE A HB2  1 c 
ATOM   2225 H HB3  . PHE A 1 144 ? 5.343   0.254   -6.758  1.000 15.088 0 159  PHE A HB3  1 c 
ATOM   2226 H HD1  . PHE A 1 144 ? 8.077   -1.071  -8.606  1.000 16.687 0 159  PHE A HD1  1 c 
ATOM   2227 H HD2  . PHE A 1 144 ? 6.026   -1.449  -5.174  1.000 17.749 0 159  PHE A HD2  1 c 
ATOM   2228 H HE1  . PHE A 1 144 ? 9.713   -2.519  -7.769  1.000 17.711 0 159  PHE A HE1  1 c 
ATOM   2229 H HE2  . PHE A 1 144 ? 7.638   -2.876  -4.348  1.000 18.557 0 159  PHE A HE2  1 c 
ATOM   2230 H HZ   . PHE A 1 144 ? 9.488   -3.419  -5.636  1.000 18.671 0 159  PHE A HZ   1 c 
ATOM   2231 N N    . ALA A 1 145 ? 3.257   -1.841  -6.635  1.000 15.266 0 160  ALA A N    1 ? 
ATOM   2232 C CA   . ALA A 1 145 ? 2.671   -2.858  -5.756  1.000 14.970 0 160  ALA A CA   1 ? 
ATOM   2233 C C    . ALA A 1 145 ? 1.899   -3.894  -6.575  1.000 15.905 0 160  ALA A C    1 ? 
ATOM   2234 O O    . ALA A 1 145 ? 1.899   -5.086  -6.227  1.000 16.443 0 160  ALA A O    1 ? 
ATOM   2235 C CB   . ALA A 1 145 ? 1.803   -2.204  -4.732  1.000 15.444 0 160  ALA A CB   1 ? 
ATOM   2236 H H    . ALA A 1 145 ? 2.963   -0.977  -6.578  1.000 15.058 0 160  ALA A H    1 c 
ATOM   2237 H HA   . ALA A 1 145 ? 3.417   -3.329  -5.291  1.000 15.280 0 160  ALA A HA   1 c 
ATOM   2238 H HB1  . ALA A 1 145 ? 2.333   -1.588  -4.199  1.000 15.300 0 160  ALA A HB1  1 c 
ATOM   2239 H HB2  . ALA A 1 145 ? 1.089   -1.714  -5.173  1.000 15.300 0 160  ALA A HB2  1 c 
ATOM   2240 H HB3  . ALA A 1 145 ? 1.416   -2.880  -4.151  1.000 15.300 0 160  ALA A HB3  1 c 
ATOM   2241 N N    . VAL A 1 146 ? 1.254   -3.443  -7.652  1.000 15.491 0 161  VAL A N    1 ? 
ATOM   2242 C CA   . VAL A 1 146 ? 0.570   -4.386  -8.537  1.000 15.359 0 161  VAL A CA   1 ? 
ATOM   2243 C C    . VAL A 1 146 ? 1.611   -5.344  -9.127  1.000 16.041 0 161  VAL A C    1 ? 
ATOM   2244 O O    . VAL A 1 146 ? 1.386   -6.565  -9.202  1.000 16.729 0 161  VAL A O    1 ? 
ATOM   2245 C CB   . VAL A 1 146 ? -0.278  -3.666  -9.610  1.000 15.542 0 161  VAL A CB   1 ? 
ATOM   2246 C CG1  . VAL A 1 146 ? -0.749  -4.635  -10.709 1.000 16.660 0 161  VAL A CG1  1 ? 
ATOM   2247 C CG2  . VAL A 1 146 ? -1.426  -2.921  -8.978  1.000 16.279 0 161  VAL A CG2  1 ? 
ATOM   2248 H H    . VAL A 1 146 ? 1.227   -2.549  -7.840  1.000 15.557 0 161  VAL A H    1 c 
ATOM   2249 H HA   . VAL A 1 146 ? -0.040  -4.914  -7.987  1.000 15.549 0 161  VAL A HA   1 c 
ATOM   2250 H HB   . VAL A 1 146 ? 0.307   -2.997  -10.037 1.000 15.847 0 161  VAL A HB   1 c 
ATOM   2251 H HG11 . VAL A 1 146 ? -1.123  -5.434  -10.299 1.000 16.325 0 161  VAL A HG11 1 c 
ATOM   2252 H HG12 . VAL A 1 146 ? 0.004   -4.882  -11.272 1.000 16.324 0 161  VAL A HG12 1 c 
ATOM   2253 H HG13 . VAL A 1 146 ? -1.429  -4.203  -11.253 1.000 16.324 0 161  VAL A HG13 1 c 
ATOM   2254 H HG21 . VAL A 1 146 ? -1.952  -2.487  -9.671  1.000 16.064 0 161  VAL A HG21 1 c 
ATOM   2255 H HG22 . VAL A 1 146 ? -1.083  -2.250  -8.367  1.000 16.063 0 161  VAL A HG22 1 c 
ATOM   2256 H HG23 . VAL A 1 146 ? -1.987  -3.545  -8.489  1.000 16.081 0 161  VAL A HG23 1 c 
ATOM   2257 N N    . VAL A 1 147 ? 2.766   -4.838  -9.607  1.000 14.408 0 162  VAL A N    1 ? 
ATOM   2258 C CA   . VAL A 1 147 ? 3.796   -5.683  -10.176 1.000 14.505 0 162  VAL A CA   1 ? 
ATOM   2259 C C    . VAL A 1 147 ? 4.373   -6.640  -9.121  1.000 16.367 0 162  VAL A C    1 ? 
ATOM   2260 O O    . VAL A 1 147 ? 4.543   -7.822  -9.407  1.000 18.300 0 162  VAL A O    1 ? 
ATOM   2261 C CB   . VAL A 1 147 ? 4.896   -4.873  -10.903 1.000 15.647 0 162  VAL A CB   1 ? 
ATOM   2262 C CG1  . VAL A 1 147 ? 6.034   -5.716  -11.448 1.000 16.876 0 162  VAL A CG1  1 ? 
ATOM   2263 C CG2  . VAL A 1 147 ? 4.304   -4.005  -12.011 1.000 15.927 0 162  VAL A CG2  1 ? 
ATOM   2264 H H    . VAL A 1 147 ? 2.909   -3.936  -9.567  1.000 14.831 0 162  VAL A H    1 c 
ATOM   2265 H HA   . VAL A 1 147 ? 3.362   -6.237  -10.854 1.000 15.053 0 162  VAL A HA   1 c 
ATOM   2266 H HB   . VAL A 1 147 ? 5.285   -4.261  -10.235 1.000 15.703 0 162  VAL A HB   1 c 
ATOM   2267 H HG11 . VAL A 1 147 ? 5.674   -6.436  -11.992 1.000 16.502 0 162  VAL A HG11 1 c 
ATOM   2268 H HG12 . VAL A 1 147 ? 6.544   -6.093  -10.710 1.000 16.502 0 162  VAL A HG12 1 c 
ATOM   2269 H HG13 . VAL A 1 147 ? 6.618   -5.161  -11.991 1.000 16.500 0 162  VAL A HG13 1 c 
ATOM   2270 H HG21 . VAL A 1 147 ? 5.019   -3.535  -12.472 1.000 15.834 0 162  VAL A HG21 1 c 
ATOM   2271 H HG22 . VAL A 1 147 ? 3.689   -3.360  -11.628 1.000 15.827 0 162  VAL A HG22 1 c 
ATOM   2272 H HG23 . VAL A 1 147 ? 3.829   -4.568  -12.645 1.000 15.839 0 162  VAL A HG23 1 c 
ATOM   2273 N N    . GLY A 1 148 ? 4.618   -6.161  -7.887  1.000 16.382 0 163  GLY A N    1 ? 
ATOM   2274 C CA   . GLY A 1 148 ? 5.130   -7.042  -6.849  1.000 16.702 0 163  GLY A CA   1 ? 
ATOM   2275 C C    . GLY A 1 148 ? 4.125   -8.124  -6.462  1.000 18.110 0 163  GLY A C    1 ? 
ATOM   2276 O O    . GLY A 1 148 ? 4.550   -9.266  -6.277  1.000 19.083 0 163  GLY A O    1 ? 
ATOM   2277 H H    . GLY A 1 148 ? 4.470   -5.279  -7.695  1.000 16.436 0 163  GLY A H    1 c 
ATOM   2278 H HA2  . GLY A 1 148 ? 5.961   -7.465  -7.169  1.000 16.944 0 163  GLY A HA2  1 c 
ATOM   2279 H HA3  . GLY A 1 148 ? 5.353   -6.503  -6.054  1.000 16.931 0 163  GLY A HA3  1 c 
ATOM   2280 N N    . ALA A 1 149 ? 2.845   -7.769  -6.428  1.000 15.708 0 164  ALA A N    1 ? 
ATOM   2281 C CA   . ALA A 1 149 ? 1.772   -8.731  -6.160  1.000 17.571 0 164  ALA A CA   1 ? 
ATOM   2282 C C    . ALA A 1 149 ? 1.733   -9.789  -7.267  1.000 19.989 0 164  ALA A C    1 ? 
ATOM   2283 O O    . ALA A 1 149 ? 1.596   -10.977 -6.974  1.000 20.051 0 164  ALA A O    1 ? 
ATOM   2284 C CB   . ALA A 1 149 ? 0.466   -8.013  -6.031  1.000 19.158 0 164  ALA A CB   1 ? 
ATOM   2285 H H    . ALA A 1 149 ? 2.622   -6.894  -6.570  1.000 16.678 0 164  ALA A H    1 c 
ATOM   2286 H HA   . ALA A 1 149 ? 1.976   -9.191  -5.299  1.000 17.888 0 164  ALA A HA   1 c 
ATOM   2287 H HB1  . ALA A 1 149 ? 0.512   -7.380  -5.296  1.000 18.677 0 164  ALA A HB1  1 c 
ATOM   2288 H HB2  . ALA A 1 149 ? 0.273   -7.535  -6.855  1.000 18.677 0 164  ALA A HB2  1 c 
ATOM   2289 H HB3  . ALA A 1 149 ? -0.245  -8.654  -5.859  1.000 18.704 0 164  ALA A HB3  1 c 
ATOM   2290 N N    . CYS A 1 150 ? 1.789   -9.345  -8.534  1.000 16.972 0 165  CYS A N    1 ? 
ATOM   2291 C CA   . CYS A 1 150 ? 1.809   -10.269 -9.665  1.000 19.159 0 165  CYS A CA   1 ? 
ATOM   2292 C C    . CYS A 1 150 ? 3.017   -11.209 -9.554  1.000 20.846 0 165  CYS A C    1 ? 
ATOM   2293 O O    . CYS A 1 150 ? 2.869   -12.425 -9.742  1.000 19.141 0 165  CYS A O    1 ? 
ATOM   2294 C CB   . CYS A 1 150 ? 1.734   -9.502  -10.998 1.000 19.587 0 165  CYS A CB   1 ? 
ATOM   2295 S SG   . CYS A 1 150 ? 0.099   -8.808  -11.304 1.000 18.703 0 165  CYS A SG   1 ? 
ATOM   2296 H H    . CYS A 1 150 ? 1.811   -8.446  -8.698  1.000 18.132 0 165  CYS A H    1 c 
ATOM   2297 H HA   . CYS A 1 150 ? 0.989   -10.824 -9.607  1.000 19.084 0 165  CYS A HA   1 c 
ATOM   2298 H HB2  . CYS A 1 150 ? 2.390   -8.770  -10.989 1.000 19.308 0 165  CYS A HB2  1 c 
ATOM   2299 H HB3  . CYS A 1 150 ? 1.963   -10.109 -11.737 1.000 19.322 0 165  CYS A HB3  1 c 
ATOM   2300 H HG   . CYS A 1 150 ? 0.346   -8.293  -12.373 0.000 18.700 0 165  CYS A HG   1 c 
ATOM   2301 N N    . GLN A 1 151 ? 4.215   -10.696 -9.268  1.000 20.526 0 166  GLN A N    1 ? 
ATOM   2302 C CA   . GLN A 1 151 ? 5.369   -11.575 -9.085  1.000 20.798 0 166  GLN A CA   1 ? 
ATOM   2303 C C    . GLN A 1 151 ? 5.082   -12.618 -7.990  1.000 20.892 0 166  GLN A C    1 ? 
ATOM   2304 O O    . GLN A 1 151 ? 5.394   -13.812 -8.168  1.000 23.243 0 166  GLN A O    1 ? 
ATOM   2305 C CB   . GLN A 1 151 ? 6.672   -10.812 -8.807  1.000 19.657 0 166  GLN A CB   1 ? 
ATOM   2306 C CG   . GLN A 1 151 ? 7.891   -11.716 -8.680  1.000 21.174 0 166  GLN A CG   1 ? 
ATOM   2307 C CD   . GLN A 1 151 ? 9.141   -11.011 -8.214  1.000 18.871 0 166  GLN A CD   1 ? 
ATOM   2308 O OE1  . GLN A 1 151 ? 9.088   -10.220 -7.272  1.000 20.751 0 166  GLN A OE1  1 ? 
ATOM   2309 N NE2  . GLN A 1 151 ? 10.261  -11.312 -8.847  1.000 21.559 0 166  GLN A NE2  1 ? 
ATOM   2310 H H    . GLN A 1 151 ? 4.322   -9.792  -9.188  1.000 20.631 0 166  GLN A H    1 c 
ATOM   2311 H HA   . GLN A 1 151 ? 5.504   -12.066 -9.935  1.000 20.539 0 166  GLN A HA   1 c 
ATOM   2312 H HB2  . GLN A 1 151 ? 6.824   -10.173 -9.535  1.000 20.251 0 166  GLN A HB2  1 c 
ATOM   2313 H HB3  . GLN A 1 151 ? 6.566   -10.300 -7.978  1.000 20.253 0 166  GLN A HB3  1 c 
ATOM   2314 H HG2  . GLN A 1 151 ? 7.693   -12.436 -8.045  1.000 20.305 0 166  GLN A HG2  1 c 
ATOM   2315 H HG3  . GLN A 1 151 ? 8.071   -12.131 -9.548  1.000 20.357 0 166  GLN A HG3  1 c 
ATOM   2316 H HE21 . GLN A 1 151 ? 10.267  -11.940 -9.473  1.000 20.821 0 166  GLN A HE21 1 c 
ATOM   2317 H HE22 . GLN A 1 151 ? 11.010  -10.884 -8.642  1.000 20.723 0 166  GLN A HE22 1 c 
ATOM   2318 N N    . ALA A 1 152 ? 4.502   -12.186 -6.880  1.000 22.553 0 167  ALA A N    1 ? 
ATOM   2319 C CA   . ALA A 1 152 ? 4.273   -13.061 -5.740  1.000 24.004 0 167  ALA A CA   1 ? 
ATOM   2320 C C    . ALA A 1 152 ? 3.324   -14.186 -6.141  1.000 24.983 0 167  ALA A C    1 ? 
ATOM   2321 O O    . ALA A 1 152 ? 3.458   -15.310 -5.641  1.000 26.960 0 167  ALA A O    1 ? 
ATOM   2322 C CB   . ALA A 1 152 ? 3.748   -12.266 -4.578  1.000 25.400 0 167  ALA A CB   1 ? 
ATOM   2323 H H    . ALA A 1 152 ? 4.241   -11.312 -6.823  1.000 22.453 0 167  ALA A H    1 c 
ATOM   2324 H HA   . ALA A 1 152 ? 5.146   -13.469 -5.484  1.000 24.117 0 167  ALA A HA   1 c 
ATOM   2325 H HB1  . ALA A 1 152 ? 4.386   -11.572 -4.342  1.000 24.968 0 167  ALA A HB1  1 c 
ATOM   2326 H HB2  . ALA A 1 152 ? 2.901   -11.854 -4.819  1.000 24.945 0 167  ALA A HB2  1 c 
ATOM   2327 H HB3  . ALA A 1 152 ? 3.614   -12.852 -3.815  1.000 24.968 0 167  ALA A HB3  1 c 
ATOM   2328 N N    . LEU A 1 153 ? 2.376   -13.881 -7.033  1.000 22.488 0 168  LEU A N    1 ? 
ATOM   2329 C CA   . LEU A 1 153 ? 1.429   -14.840 -7.599  1.000 22.797 0 168  LEU A CA   1 ? 
ATOM   2330 C C    . LEU A 1 153 ? 2.034   -15.722 -8.703  1.000 22.938 0 168  LEU A C    1 ? 
ATOM   2331 O O    . LEU A 1 153 ? 1.312   -16.582 -9.204  1.000 27.689 0 168  LEU A O    1 ? 
ATOM   2332 C CB   . LEU A 1 153 ? 0.205   -14.089 -8.133  1.000 20.371 0 168  LEU A CB   1 ? 
ATOM   2333 C CG   . LEU A 1 153 ? -0.686  -13.409 -7.089  1.000 21.429 0 168  LEU A CG   1 ? 
ATOM   2334 C CD1  . LEU A 1 153 ? -1.556  -12.359 -7.676  1.000 21.502 0 168  LEU A CD1  1 ? 
ATOM   2335 C CD2  . LEU A 1 153 ? -1.556  -14.425 -6.324  1.000 25.238 0 168  LEU A CD2  1 ? 
ATOM   2336 H H    . LEU A 1 153 ? 2.306   -13.010 -7.300  1.000 23.084 0 168  LEU A H    1 c 
ATOM   2337 H HA   . LEU A 1 153 ? 1.134   -15.437 -6.866  1.000 22.345 0 168  LEU A HA   1 c 
ATOM   2338 H HB2  . LEU A 1 153 ? 0.519   -13.402 -8.766  1.000 21.164 0 168  LEU A HB2  1 c 
ATOM   2339 H HB3  . LEU A 1 153 ? -0.348  -14.725 -8.642  1.000 21.186 0 168  LEU A HB3  1 c 
ATOM   2340 H HG   . LEU A 1 153 ? -0.094  -12.969 -6.427  1.000 21.886 0 168  LEU A HG   1 c 
ATOM   2341 H HD11 . LEU A 1 153 ? -1.003  -11.664 -8.071  1.000 21.488 0 168  LEU A HD11 1 c 
ATOM   2342 H HD12 . LEU A 1 153 ? -2.114  -11.972 -6.981  1.000 21.513 0 168  LEU A HD12 1 c 
ATOM   2343 H HD13 . LEU A 1 153 ? -2.121  -12.752 -8.363  1.000 21.488 0 168  LEU A HD13 1 c 
ATOM   2344 H HD21 . LEU A 1 153 ? -0.984  -15.054 -5.853  1.000 24.046 0 168  LEU A HD21 1 c 
ATOM   2345 H HD22 . LEU A 1 153 ? -2.119  -14.909 -6.952  1.000 24.055 0 168  LEU A HD22 1 c 
ATOM   2346 H HD23 . LEU A 1 153 ? -2.117  -13.957 -5.683  1.000 24.043 0 168  LEU A HD23 1 c 
ATOM   2347 N N    . GLY A 1 154 ? 3.274   -15.513 -9.169  1.000 21.836 0 169  GLY A N    1 ? 
ATOM   2348 C CA   . GLY A 1 154 ? 3.894   -16.325 -10.207 1.000 23.903 0 169  GLY A CA   1 ? 
ATOM   2349 C C    . GLY A 1 154 ? 3.622   -15.851 -11.636 1.000 24.998 0 169  GLY A C    1 ? 
ATOM   2350 O O    . GLY A 1 154 ? 3.867   -16.585 -12.607 1.000 27.330 0 169  GLY A O    1 ? 
ATOM   2351 H H    . GLY A 1 154 ? 3.759   -14.821 -8.823  1.000 22.553 0 169  GLY A H    1 c 
ATOM   2352 H HA2  . GLY A 1 154 ? 4.866   -16.336 -10.055 1.000 23.700 0 169  GLY A HA2  1 c 
ATOM   2353 H HA3  . GLY A 1 154 ? 3.573   -17.253 -10.113 1.000 23.658 0 169  GLY A HA3  1 c 
ATOM   2354 N N    . LEU A 1 155 ? 3.182   -14.597 -11.778 1.000 22.914 0 170  LEU A N    1 ? 
ATOM   2355 C CA   . LEU A 1 155 ? 2.808   -13.983 -13.056 1.000 20.183 0 170  LEU A CA   1 ? 
ATOM   2356 C C    . LEU A 1 155 ? 4.000   -13.246 -13.652 1.000 23.649 0 170  LEU A C    1 ? 
ATOM   2357 O O    . LEU A 1 155 ? 4.154   -12.008 -13.539 1.000 25.593 0 170  LEU A O    1 ? 
ATOM   2358 C CB   . LEU A 1 155 ? 1.582   -13.085 -12.874 1.000 20.531 0 170  LEU A CB   1 ? 
ATOM   2359 C CG   . LEU A 1 155 ? 0.392   -13.652 -12.122 1.000 20.935 0 170  LEU A CG   1 ? 
ATOM   2360 C CD1  . LEU A 1 155 ? -0.732  -12.612 -12.044 1.000 23.314 0 170  LEU A CD1  1 ? 
ATOM   2361 C CD2  . LEU A 1 155 ? -0.125  -14.946 -12.715 1.000 22.825 0 170  LEU A CD2  1 ? 
ATOM   2362 H H    . LEU A 1 155 ? 3.113   -14.081 -11.027 1.000 22.718 0 170  LEU A H    1 c 
ATOM   2363 H HA   . LEU A 1 155 ? 2.565   -14.714 -13.679 1.000 21.447 0 170  LEU A HA   1 c 
ATOM   2364 H HB2  . LEU A 1 155 ? 1.873   -12.267 -12.410 1.000 20.559 0 170  LEU A HB2  1 c 
ATOM   2365 H HB3  . LEU A 1 155 ? 1.275   -12.808 -13.768 1.000 20.546 0 170  LEU A HB3  1 c 
ATOM   2366 H HG   . LEU A 1 155 ? 0.683   -13.845 -11.194 1.000 21.632 0 170  LEU A HG   1 c 
ATOM   2367 H HD11 . LEU A 1 155 ? -0.395  -11.798 -11.634 1.000 22.585 0 170  LEU A HD11 1 c 
ATOM   2368 H HD12 . LEU A 1 155 ? -1.464  -12.964 -11.510 1.000 22.570 0 170  LEU A HD12 1 c 
ATOM   2369 H HD13 . LEU A 1 155 ? -1.053  -12.413 -12.940 1.000 22.585 0 170  LEU A HD13 1 c 
ATOM   2370 H HD21 . LEU A 1 155 ? 0.576   -15.618 -12.693 1.000 22.307 0 170  LEU A HD21 1 c 
ATOM   2371 H HD22 . LEU A 1 155 ? -0.397  -14.790 -13.633 1.000 22.564 0 170  LEU A HD22 1 c 
ATOM   2372 H HD23 . LEU A 1 155 ? -0.888  -15.258 -12.200 1.000 22.320 0 170  LEU A HD23 1 c 
ATOM   2373 N N    . ARG A 1 156 ? 4.852   -14.030 -14.313 1.000 22.779 0 171  ARG A N    1 ? 
ATOM   2374 C CA   . ARG A 1 156 ? 6.184   -13.615 -14.705 1.000 23.821 0 171  ARG A CA   1 ? 
ATOM   2375 C C    . ARG A 1 156 ? 6.104   -12.570 -15.822 1.000 22.523 0 171  ARG A C    1 ? 
ATOM   2376 O O    . ARG A 1 156 ? 7.096   -11.905 -16.091 1.000 24.887 0 171  ARG A O    1 ? 
ATOM   2377 C CB   . ARG A 1 156 ? 7.054   -14.799 -15.139 1.000 30.629 0 171  ARG A CB   1 ? 
ATOM   2378 C CG   . ARG A 1 156 ? 7.359   -15.731 -13.967 1.000 40.939 0 171  ARG A CG   1 ? 
ATOM   2379 C CD   . ARG A 1 156 ? 8.463   -16.764 -14.280 1.000 49.959 0 171  ARG A CD   1 ? 
ATOM   2380 N NE   . ARG A 1 156 ? 8.427   -17.214 -15.682 1.000 58.405 0 171  ARG A NE   1 ? 
ATOM   2381 C CZ   . ARG A 1 156 ? 8.146   -18.431 -16.169 1.000 76.389 0 171  ARG A CZ   1 ? 
ATOM   2382 N NH1  . ARG A 1 156 ? 8.035   -18.593 -17.482 1.000 77.184 0 171  ARG A NH1  1 ? 
ATOM   2383 N NH2  . ARG A 1 156 ? 7.945   -19.466 -15.366 1.000 80.075 0 171  ARG A NH2  1 ? 
ATOM   2384 H H    . ARG A 1 156 ? 4.584   -14.875 -14.534 1.000 23.222 0 171  ARG A H    1 c 
ATOM   2385 H HA   . ARG A 1 156 ? 6.613   -13.191 -13.922 1.000 24.607 0 171  ARG A HA   1 c 
ATOM   2386 H HB2  . ARG A 1 156 ? 6.588   -15.303 -15.840 1.000 31.036 0 171  ARG A HB2  1 c 
ATOM   2387 H HB3  . ARG A 1 156 ? 7.897   -14.464 -15.513 1.000 31.019 0 171  ARG A HB3  1 c 
ATOM   2388 H HG2  . ARG A 1 156 ? 7.638   -15.196 -13.194 1.000 39.905 0 171  ARG A HG2  1 c 
ATOM   2389 H HG3  . ARG A 1 156 ? 6.538   -16.210 -13.717 1.000 40.036 0 171  ARG A HG3  1 c 
ATOM   2390 H HD2  . ARG A 1 156 ? 9.336   -16.364 -14.094 1.000 49.667 0 171  ARG A HD2  1 c 
ATOM   2391 H HD3  . ARG A 1 156 ? 8.354   -17.536 -13.689 1.000 49.998 0 171  ARG A HD3  1 c 
ATOM   2392 H HE   . ARG A 1 156 ? 8.627   -16.615 -16.282 1.000 59.686 0 171  ARG A HE   1 c 
ATOM   2393 H HH11 . ARG A 1 156 ? 8.241   -19.373 -17.846 1.000 76.886 0 171  ARG A HH11 1 c 
ATOM   2394 H HH12 . ARG A 1 156 ? 7.754   -17.923 -17.987 1.000 76.622 0 171  ARG A HH12 1 c 
ATOM   2395 H HH21 . ARG A 1 156 ? 7.279   -20.026 -15.531 1.000 78.795 0 171  ARG A HH21 1 c 
ATOM   2396 H HH22 . ARG A 1 156 ? 8.478   -19.597 -14.671 1.000 78.384 0 171  ARG A HH22 1 c 
ATOM   2397 N N    . ASP A 1 157 ? 4.938   -12.459 -16.497 1.000 20.444 0 172  ASP A N    1 ? 
ATOM   2398 C CA   . ASP A 1 157 ? 4.840   -11.618 -17.675 1.000 19.437 0 172  ASP A CA   1 ? 
ATOM   2399 C C    . ASP A 1 157 ? 4.408   -10.187 -17.319 1.000 19.073 0 172  ASP A C    1 ? 
ATOM   2400 O O    . ASP A 1 157 ? 4.478   -9.328  -18.206 1.000 19.785 0 172  ASP A O    1 ? 
ATOM   2401 C CB   . ASP A 1 157 ? 3.831   -12.174 -18.672 1.000 20.337 0 172  ASP A CB   1 ? 
ATOM   2402 C CG   . ASP A 1 157 ? 2.417   -12.302 -18.141 1.000 21.530 0 172  ASP A CG   1 ? 
ATOM   2403 O OD1  . ASP A 1 157 ? 2.274   -12.832 -17.003 1.000 20.464 0 172  ASP A OD1  1 ? 
ATOM   2404 O OD2  . ASP A 1 157 ? 1.469   -11.809 -18.818 1.000 20.016 0 172  ASP A OD2  1 ? 
ATOM   2405 H H    . ASP A 1 157 ? 4.202   -12.926 -16.222 1.000 20.739 0 172  ASP A H    1 c 
ATOM   2406 H HA   . ASP A 1 157 ? 5.720   -11.585 -18.114 1.000 19.768 0 172  ASP A HA   1 c 
ATOM   2407 H HB2  . ASP A 1 157 ? 3.812   -11.595 -19.462 1.000 20.383 0 172  ASP A HB2  1 c 
ATOM   2408 H HB3  . ASP A 1 157 ? 4.130   -13.063 -18.958 1.000 20.393 0 172  ASP A HB3  1 c 
ATOM   2409 N N    . VAL A 1 158 ? 4.023   -9.925  -16.067 1.000 17.593 0 173  VAL A N    1 ? 
ATOM   2410 C CA   . VAL A 1 158 ? 3.495   -8.613  -15.690 1.000 17.331 0 173  VAL A CA   1 ? 
ATOM   2411 C C    . VAL A 1 158 ? 4.679   -7.748  -15.260 1.000 18.258 0 173  VAL A C    1 ? 
ATOM   2412 O O    . VAL A 1 158 ? 5.409   -8.135  -14.345 1.000 19.390 0 173  VAL A O    1 ? 
ATOM   2413 C CB   . VAL A 1 158 ? 2.436   -8.657  -14.589 1.000 17.787 0 173  VAL A CB   1 ? 
ATOM   2414 C CG1  . VAL A 1 158 ? 1.882   -7.287  -14.277 1.000 18.347 0 173  VAL A CG1  1 ? 
ATOM   2415 C CG2  . VAL A 1 158 ? 1.246   -9.529  -14.952 1.000 18.450 0 173  VAL A CG2  1 ? 
ATOM   2416 H H    . VAL A 1 158 ? 4.085   -10.574 -15.427 1.000 17.926 0 173  VAL A H    1 c 
ATOM   2417 H HA   . VAL A 1 158 ? 3.090   -8.211  -16.481 1.000 17.634 0 173  VAL A HA   1 c 
ATOM   2418 H HB   . VAL A 1 158 ? 2.861   -9.020  -13.777 1.000 17.925 0 173  VAL A HB   1 c 
ATOM   2419 H HG11 . VAL A 1 158 ? 1.558   -6.874  -15.095 1.000 18.180 0 173  VAL A HG11 1 c 
ATOM   2420 H HG12 . VAL A 1 158 ? 2.580   -6.733  -13.889 1.000 18.180 0 173  VAL A HG12 1 c 
ATOM   2421 H HG13 . VAL A 1 158 ? 1.149   -7.368  -13.644 1.000 18.183 0 173  VAL A HG13 1 c 
ATOM   2422 H HG21 . VAL A 1 158 ? 0.615   -9.544  -14.213 1.000 18.251 0 173  VAL A HG21 1 c 
ATOM   2423 H HG22 . VAL A 1 158 ? 1.551   -10.434 -15.135 1.000 18.248 0 173  VAL A HG22 1 c 
ATOM   2424 H HG23 . VAL A 1 158 ? 0.810   -9.170  -15.743 1.000 18.251 0 173  VAL A HG23 1 c 
ATOM   2425 N N    . HIS A 1 159 ? 4.859   -6.612  -15.940 1.000 15.343 0 174  HIS A N    1 ? 
ATOM   2426 C CA   . HIS A 1 159 ? 5.986   -5.735  -15.661 1.000 15.671 0 174  HIS A CA   1 ? 
ATOM   2427 C C    . HIS A 1 159 ? 5.548   -4.262  -15.597 1.000 15.676 0 174  HIS A C    1 ? 
ATOM   2428 O O    . HIS A 1 159 ? 4.494   -3.851  -16.062 1.000 15.575 0 174  HIS A O    1 ? 
ATOM   2429 C CB   . HIS A 1 159 ? 7.034   -5.851  -16.768 1.000 17.341 0 174  HIS A CB   1 ? 
ATOM   2430 C CG   . HIS A 1 159 ? 7.811   -7.119  -16.698 1.000 17.717 0 174  HIS A CG   1 ? 
ATOM   2431 N ND1  . HIS A 1 159 ? 8.716   -7.316  -15.682 1.000 20.460 0 174  HIS A ND1  1 ? 
ATOM   2432 C CD2  . HIS A 1 159 ? 7.807   -8.283  -17.421 1.000 20.932 0 174  HIS A CD2  1 ? 
ATOM   2433 C CE1  . HIS A 1 159 ? 9.232   -8.545  -15.802 1.000 22.676 0 174  HIS A CE1  1 ? 
ATOM   2434 N NE2  . HIS A 1 159 ? 8.728   -9.139  -16.873 1.000 22.524 0 174  HIS A NE2  1 ? 
ATOM   2435 H H    . HIS A 1 159 ? 4.265   -6.375  -16.593 1.000 16.092 0 174  HIS A H    1 c 
ATOM   2436 H HA   . HIS A 1 159 ? 6.386   -5.983  -14.793 1.000 15.938 0 174  HIS A HA   1 c 
ATOM   2437 H HB2  . HIS A 1 159 ? 6.583   -5.799  -17.638 1.000 17.061 0 174  HIS A HB2  1 c 
ATOM   2438 H HB3  . HIS A 1 159 ? 7.652   -5.092  -16.698 1.000 17.026 0 174  HIS A HB3  1 c 
ATOM   2439 H HD1  . HIS A 1 159 ? 8.890   -6.741  -15.038 0.000 20.400 0 174  HIS A HD1  1 c 
ATOM   2440 H HD2  . HIS A 1 159 ? 7.297   -8.456  -18.187 1.000 20.524 0 174  HIS A HD2  1 c 
ATOM   2441 H HE1  . HIS A 1 159 ? 9.895   -8.902  -15.243 1.000 22.107 0 174  HIS A HE1  1 c 
ATOM   2442 H HE2  . HIS A 1 159 ? 8.925   -9.948  -17.147 0.000 22.530 0 174  HIS A HE2  1 c 
ATOM   2443 N N    . LEU A 1 160 ? 6.372   -3.465  -14.924 1.000 14.348 0 175  LEU A N    1 ? 
ATOM   2444 C CA   . LEU A 1 160 ? 6.142   -2.036  -14.755 1.000 14.232 0 175  LEU A CA   1 ? 
ATOM   2445 C C    . LEU A 1 160 ? 6.500   -1.290  -16.036 1.000 14.585 0 175  LEU A C    1 ? 
ATOM   2446 O O    . LEU A 1 160 ? 7.552   -1.526  -16.598 1.000 15.062 0 175  LEU A O    1 ? 
ATOM   2447 C CB   . LEU A 1 160 ? 7.043   -1.591  -13.599 1.000 14.193 0 175  LEU A CB   1 ? 
ATOM   2448 C CG   . LEU A 1 160 ? 6.837   -0.181  -13.057 1.000 14.577 0 175  LEU A CG   1 ? 
ATOM   2449 C CD1  . LEU A 1 160 ? 5.468   0.017   -12.511 1.000 16.103 0 175  LEU A CD1  1 ? 
ATOM   2450 C CD2  . LEU A 1 160 ? 7.891   0.103   -11.983 1.000 14.881 0 175  LEU A CD2  1 ? 
ATOM   2451 H H    . LEU A 1 160 ? 7.124   -3.829  -14.553 1.000 14.639 0 175  LEU A H    1 c 
ATOM   2452 H HA   . LEU A 1 160 ? 5.191   -1.885  -14.523 1.000 14.334 0 175  LEU A HA   1 c 
ATOM   2453 H HB2  . LEU A 1 160 ? 6.921   -2.226  -12.856 1.000 14.301 0 175  LEU A HB2  1 c 
ATOM   2454 H HB3  . LEU A 1 160 ? 7.979   -1.673  -13.894 1.000 14.293 0 175  LEU A HB3  1 c 
ATOM   2455 H HG   . LEU A 1 160 ? 6.970   0.462   -13.801 1.000 14.838 0 175  LEU A HG   1 c 
ATOM   2456 H HD11 . LEU A 1 160 ? 4.821   -0.009  -13.235 1.000 15.603 0 175  LEU A HD11 1 c 
ATOM   2457 H HD12 . LEU A 1 160 ? 5.418   0.879   -12.064 1.000 15.612 0 175  LEU A HD12 1 c 
ATOM   2458 H HD13 . LEU A 1 160 ? 5.268   -0.689  -11.873 1.000 15.619 0 175  LEU A HD13 1 c 
ATOM   2459 H HD21 . LEU A 1 160 ? 8.778   0.037   -12.374 1.000 14.793 0 175  LEU A HD21 1 c 
ATOM   2460 H HD22 . LEU A 1 160 ? 7.805   -0.545  -11.264 1.000 14.793 0 175  LEU A HD22 1 c 
ATOM   2461 H HD23 . LEU A 1 160 ? 7.760   0.999   -11.629 1.000 14.802 0 175  LEU A HD23 1 c 
ATOM   2462 N N    . ALA A 1 161 ? 5.609   -0.389  -16.420 1.000 13.771 0 176  ALA A N    1 ? 
ATOM   2463 C CA   . ALA A 1 161 ? 5.846   0.548   -17.504 1.000 14.057 0 176  ALA A CA   1 ? 
ATOM   2464 C C    . ALA A 1 161 ? 5.898   1.967   -16.898 1.000 14.143 0 176  ALA A C    1 ? 
ATOM   2465 O O    . ALA A 1 161 ? 5.093   2.307   -16.050 1.000 14.638 0 176  ALA A O    1 ? 
ATOM   2466 C CB   . ALA A 1 161 ? 4.759   0.441   -18.520 1.000 17.139 0 176  ALA A CB   1 ? 
ATOM   2467 H H    . ALA A 1 161 ? 4.805   -0.353  -15.987 1.000 14.030 0 176  ALA A H    1 c 
ATOM   2468 H HA   . ALA A 1 161 ? 6.723   0.343   -17.924 1.000 14.551 0 176  ALA A HA   1 c 
ATOM   2469 H HB1  . ALA A 1 161 ? 4.741   -0.460  -18.885 1.000 16.178 0 176  ALA A HB1  1 c 
ATOM   2470 H HB2  . ALA A 1 161 ? 3.902   0.636   -18.104 1.000 16.145 0 176  ALA A HB2  1 c 
ATOM   2471 H HB3  . ALA A 1 161 ? 4.918   1.075   -19.238 1.000 16.153 0 176  ALA A HB3  1 c 
ATOM   2472 N N    . LEU A 1 162 ? 6.844   2.792   -17.376 1.000 13.635 0 177  LEU A N    1 ? 
ATOM   2473 C CA   . LEU A 1 162 ? 7.103   4.101   -16.792 1.000 14.363 0 177  LEU A CA   1 ? 
ATOM   2474 C C    . LEU A 1 162 ? 7.270   5.148   -17.893 1.000 13.152 0 177  LEU A C    1 ? 
ATOM   2475 O O    . LEU A 1 162 ? 8.072   4.972   -18.797 1.000 14.428 0 177  LEU A O    1 ? 
ATOM   2476 C CB   . LEU A 1 162 ? 8.386   4.071   -15.979 1.000 14.705 0 177  LEU A CB   1 ? 
ATOM   2477 C CG   . LEU A 1 162 ? 8.394   3.144   -14.754 1.000 15.828 0 177  LEU A CG   1 ? 
ATOM   2478 C CD1  . LEU A 1 162 ? 9.804   2.988   -14.248 1.000 16.056 0 177  LEU A CD1  1 ? 
ATOM   2479 C CD2  . LEU A 1 162 ? 7.441   3.603   -13.663 1.000 15.556 0 177  LEU A CD2  1 ? 
ATOM   2480 H H    . LEU A 1 162 ? 7.343   2.528   -18.094 1.000 13.918 0 177  LEU A H    1 c 
ATOM   2481 H HA   . LEU A 1 162 ? 6.344   4.355   -16.208 1.000 14.071 0 177  LEU A HA   1 c 
ATOM   2482 H HB2  . LEU A 1 162 ? 9.121   3.802   -16.576 1.000 14.885 0 177  LEU A HB2  1 c 
ATOM   2483 H HB3  . LEU A 1 162 ? 8.577   4.988   -15.673 1.000 14.864 0 177  LEU A HB3  1 c 
ATOM   2484 H HG   . LEU A 1 162 ? 8.089   2.248   -15.052 1.000 15.591 0 177  LEU A HG   1 c 
ATOM   2485 H HD11 . LEU A 1 162 ? 10.356  2.589   -14.942 1.000 15.980 0 177  LEU A HD11 1 c 
ATOM   2486 H HD12 . LEU A 1 162 ? 9.806   2.413   -13.464 1.000 15.986 0 177  LEU A HD12 1 c 
ATOM   2487 H HD13 . LEU A 1 162 ? 10.162  3.859   -14.011 1.000 15.986 0 177  LEU A HD13 1 c 
ATOM   2488 H HD21 . LEU A 1 162 ? 6.528   3.580   -13.997 1.000 15.617 0 177  LEU A HD21 1 c 
ATOM   2489 H HD22 . LEU A 1 162 ? 7.664   4.511   -13.397 1.000 15.630 0 177  LEU A HD22 1 c 
ATOM   2490 H HD23 . LEU A 1 162 ? 7.517   3.013   -12.895 1.000 15.626 0 177  LEU A HD23 1 c 
ATOM   2491 N N    . SER A 1 163 ? 6.516   6.237   -17.801 1.000 14.183 0 178  SER A N    1 ? 
ATOM   2492 C CA   . SER A 1 163 ? 6.846   7.447   -18.537 1.000 13.325 0 178  SER A CA   1 ? 
ATOM   2493 C C    . SER A 1 163 ? 7.601   8.390   -17.612 1.000 12.936 0 178  SER A C    1 ? 
ATOM   2494 O O    . SER A 1 163 ? 8.052   7.968   -16.549 1.000 14.753 0 178  SER A O    1 ? 
ATOM   2495 C CB   . SER A 1 163 ? 5.644   8.120   -19.161 1.000 13.614 0 178  SER A CB   1 ? 
ATOM   2496 O OG   . SER A 1 163 ? 4.766   8.742   -18.228 1.000 14.547 0 178  SER A OG   1 ? 
ATOM   2497 H H    . SER A 1 163 ? 5.772   6.231   -17.270 1.000 13.743 0 178  SER A H    1 c 
ATOM   2498 H HA   . SER A 1 163 ? 7.461   7.196   -19.270 1.000 13.484 0 178  SER A HA   1 c 
ATOM   2499 H HB2  . SER A 1 163 ? 5.951   8.788   -19.801 1.000 13.764 0 178  SER A HB2  1 c 
ATOM   2500 H HB3  . SER A 1 163 ? 5.141   7.452   -19.665 1.000 13.763 0 178  SER A HB3  1 c 
ATOM   2501 H HG   . SER A 1 163 ? 4.123   9.092   -18.656 0.000 14.560 0 178  SER A HG   1 c 
ATOM   2502 N N    . GLU A 1 164 ? 7.720   9.664   -17.993 1.000 14.004 0 179  GLU A N    1 ? 
ATOM   2503 C CA   . GLU A 1 164 ? 8.378   10.653  -17.162 1.000 13.917 0 179  GLU A CA   1 ? 
ATOM   2504 C C    . GLU A 1 164 ? 7.438   11.216  -16.081 1.000 15.323 0 179  GLU A C    1 ? 
ATOM   2505 O O    . GLU A 1 164 ? 7.913   11.934  -15.201 1.000 15.169 0 179  GLU A O    1 ? 
ATOM   2506 C CB   . GLU A 1 164 ? 9.096   11.708  -17.987 1.000 14.875 0 179  GLU A CB   1 ? 
ATOM   2507 C CG   . GLU A 1 164 ? 10.267  11.157  -18.785 1.000 14.697 0 179  GLU A CG   1 ? 
ATOM   2508 C CD   . GLU A 1 164 ? 11.071  12.219  -19.509 1.000 14.285 0 179  GLU A CD   1 ? 
ATOM   2509 O OE1  . GLU A 1 164 ? 10.460  13.053  -20.251 1.000 14.447 0 179  GLU A OE1  1 ? 
ATOM   2510 O OE2  . GLU A 1 164 ? 12.302  12.223  -19.349 1.000 15.230 0 179  GLU A OE2  1 ? 
ATOM   2511 H H    . GLU A 1 164 ? 7.396   9.924   -18.806 1.000 13.727 0 179  GLU A H    1 c 
ATOM   2512 H HA   . GLU A 1 164 ? 9.104   10.182  -16.678 1.000 14.385 0 179  GLU A HA   1 c 
ATOM   2513 H HB2  . GLU A 1 164 ? 8.454   12.113  -18.608 1.000 14.615 0 179  GLU A HB2  1 c 
ATOM   2514 H HB3  . GLU A 1 164 ? 9.415   12.413  -17.388 1.000 14.627 0 179  GLU A HB3  1 c 
ATOM   2515 H HG2  . GLU A 1 164 ? 10.866  10.671  -18.180 1.000 14.643 0 179  GLU A HG2  1 c 
ATOM   2516 H HG3  . GLU A 1 164 ? 9.930   10.517  -19.447 1.000 14.642 0 179  GLU A HG3  1 c 
ATOM   2517 N N    . ASP A 1 165 ? 6.139   10.865  -16.088 1.000 14.247 0 180  ASP A N    1 ? 
ATOM   2518 C CA   . ASP A 1 165 ? 5.230   11.332  -15.060 1.000 15.019 0 180  ASP A CA   1 ? 
ATOM   2519 C C    . ASP A 1 165 ? 4.056   10.378  -14.776 1.000 14.680 0 180  ASP A C    1 ? 
ATOM   2520 O O    . ASP A 1 165 ? 3.075   10.790  -14.157 1.000 16.484 0 180  ASP A O    1 ? 
ATOM   2521 C CB   . ASP A 1 165 ? 4.624   12.677  -15.449 1.000 16.072 0 180  ASP A CB   1 ? 
ATOM   2522 C CG   . ASP A 1 165 ? 3.948   13.452  -14.324 1.000 17.941 0 180  ASP A CG   1 ? 
ATOM   2523 O OD1  . ASP A 1 165 ? 4.565   13.529  -13.230 1.000 19.600 0 180  ASP A OD1  1 ? 
ATOM   2524 O OD2  . ASP A 1 165 ? 2.771   13.902  -14.531 1.000 19.943 0 180  ASP A OD2  1 ? 
ATOM   2525 H H    . ASP A 1 165 ? 5.810   10.355  -16.772 1.000 14.652 0 180  ASP A H    1 c 
ATOM   2526 H HA   . ASP A 1 165 ? 5.738   11.452  -14.228 1.000 15.087 0 180  ASP A HA   1 c 
ATOM   2527 H HB2  . ASP A 1 165 ? 5.341   13.236  -15.805 1.000 16.217 0 180  ASP A HB2  1 c 
ATOM   2528 H HB3  . ASP A 1 165 ? 3.969   12.538  -16.164 1.000 16.254 0 180  ASP A HB3  1 c 
ATOM   2529 N N    . HIS A 1 166 ? 4.181   9.127   -15.212 1.000 14.361 0 181  HIS A N    1 ? 
ATOM   2530 C CA   . HIS A 1 166 ? 3.128   8.135   -14.970 1.000 15.048 0 181  HIS A CA   1 ? 
ATOM   2531 C C    . HIS A 1 166 ? 3.682   6.716   -15.016 1.000 14.912 0 181  HIS A C    1 ? 
ATOM   2532 O O    . HIS A 1 166 ? 4.759   6.467   -15.520 1.000 14.020 0 181  HIS A O    1 ? 
ATOM   2533 C CB   . HIS A 1 166 ? 1.990   8.398   -15.948 1.000 15.674 0 181  HIS A CB   1 ? 
ATOM   2534 C CG   . HIS A 1 166 ? 0.750   7.620   -15.745 1.000 15.369 0 181  HIS A CG   1 ? 
ATOM   2535 N ND1  . HIS A 1 166 ? 0.229   7.417   -14.481 1.000 17.753 0 181  HIS A ND1  1 ? 
ATOM   2536 C CD2  . HIS A 1 166 ? -0.062  6.977   -16.616 1.000 16.820 0 181  HIS A CD2  1 ? 
ATOM   2537 C CE1  . HIS A 1 166 ? -0.916  6.736   -14.621 1.000 18.477 0 181  HIS A CE1  1 ? 
ATOM   2538 N NE2  . HIS A 1 166 ? -1.078  6.417   -15.886 1.000 16.462 0 181  HIS A NE2  1 ? 
ATOM   2539 H H    . HIS A 1 166 ? 4.936   8.869   -15.656 1.000 14.591 0 181  HIS A H    1 c 
ATOM   2540 H HA   . HIS A 1 166 ? 2.783   8.291   -14.057 1.000 15.070 0 181  HIS A HA   1 c 
ATOM   2541 H HB2  . HIS A 1 166 ? 1.766   9.353   -15.912 1.000 15.482 0 181  HIS A HB2  1 c 
ATOM   2542 H HB3  . HIS A 1 166 ? 2.321   8.225   -16.856 1.000 15.463 0 181  HIS A HB3  1 c 
ATOM   2543 H HD1  . HIS A 1 166 ? 0.577   7.722   -13.730 0.000 17.740 0 181  HIS A HD1  1 c 
ATOM   2544 H HD2  . HIS A 1 166 ? 0.041   6.923   -17.545 1.000 16.411 0 181  HIS A HD2  1 c 
ATOM   2545 H HE1  . HIS A 1 166 ? -1.460  6.447   -13.908 1.000 17.793 0 181  HIS A HE1  1 c 
ATOM   2546 H HE2  . HIS A 1 166 ? -1.755  5.972   -16.217 0.000 16.490 0 181  HIS A HE2  1 c 
ATOM   2547 N N    . ALA A 1 167 ? 2.883   5.761   -14.500 1.000 13.848 0 182  ALA A N    1 ? 
ATOM   2548 C CA   . ALA A 1 167 ? 3.251   4.371   -14.390 1.000 14.946 0 182  ALA A CA   1 ? 
ATOM   2549 C C    . ALA A 1 167 ? 2.004   3.532   -14.646 1.000 14.335 0 182  ALA A C    1 ? 
ATOM   2550 O O    . ALA A 1 167 ? 0.917   3.935   -14.251 1.000 15.543 0 182  ALA A O    1 ? 
ATOM   2551 C CB   . ALA A 1 167 ? 3.794   4.060   -12.992 1.000 15.980 0 182  ALA A CB   1 ? 
ATOM   2552 H H    . ALA A 1 167 ? 2.067   6.011   -14.176 1.000 14.382 0 182  ALA A H    1 c 
ATOM   2553 H HA   . ALA A 1 167 ? 3.936   4.160   -15.079 1.000 14.778 0 182  ALA A HA   1 c 
ATOM   2554 H HB1  . ALA A 1 167 ? 4.579   4.606   -12.817 1.000 15.670 0 182  ALA A HB1  1 c 
ATOM   2555 H HB2  . ALA A 1 167 ? 3.113   4.255   -12.326 1.000 15.670 0 182  ALA A HB2  1 c 
ATOM   2556 H HB3  . ALA A 1 167 ? 4.037   3.121   -12.937 1.000 15.670 0 182  ALA A HB3  1 c 
ATOM   2557 N N    . TRP A 1 168 ? 2.246   2.390   -15.281 1.000 14.303 0 183  TRP A N    1 ? 
ATOM   2558 C CA   . TRP A 1 168 ? 1.198   1.418   -15.566 1.000 14.571 0 183  TRP A CA   1 ? 
ATOM   2559 C C    . TRP A 1 168 ? 1.888   0.047   -15.684 1.000 16.192 0 183  TRP A C    1 ? 
ATOM   2560 O O    . TRP A 1 168 ? 3.044   -0.128  -15.261 1.000 14.689 0 183  TRP A O    1 ? 
ATOM   2561 C CB   . TRP A 1 168 ? 0.383   1.902   -16.777 1.000 14.377 0 183  TRP A CB   1 ? 
ATOM   2562 C CG   . TRP A 1 168 ? 1.134   1.989   -18.078 1.000 15.266 0 183  TRP A CG   1 ? 
ATOM   2563 C CD1  . TRP A 1 168 ? 1.228   1.054   -19.062 1.000 14.063 0 183  TRP A CD1  1 ? 
ATOM   2564 C CD2  . TRP A 1 168 ? 1.873   3.143   -18.565 1.000 14.376 0 183  TRP A CD2  1 ? 
ATOM   2565 N NE1  . TRP A 1 168 ? 2.002   1.512   -20.112 1.000 15.261 0 183  TRP A NE1  1 ? 
ATOM   2566 C CE2  . TRP A 1 168 ? 2.357   2.810   -19.851 1.000 14.836 0 183  TRP A CE2  1 ? 
ATOM   2567 C CE3  . TRP A 1 168 ? 2.093   4.435   -18.062 1.000 14.880 0 183  TRP A CE3  1 ? 
ATOM   2568 C CZ2  . TRP A 1 168 ? 3.107   3.698   -20.621 1.000 14.410 0 183  TRP A CZ2  1 ? 
ATOM   2569 C CZ3  . TRP A 1 168 ? 2.854   5.306   -18.823 1.000 15.603 0 183  TRP A CZ3  1 ? 
ATOM   2570 C CH2  . TRP A 1 168 ? 3.327   4.945   -20.070 1.000 15.153 0 183  TRP A CH2  1 ? 
ATOM   2571 H H    . TRP A 1 168 ? 3.100   2.204   -15.552 1.000 14.390 0 183  TRP A H    1 c 
ATOM   2572 H HA   . TRP A 1 168 ? 0.587   1.388   -14.781 1.000 14.765 0 183  TRP A HA   1 c 
ATOM   2573 H HB2  . TRP A 1 168 ? -0.382  1.301   -16.895 1.000 14.648 0 183  TRP A HB2  1 c 
ATOM   2574 H HB3  . TRP A 1 168 ? 0.017   2.788   -16.567 1.000 14.626 0 183  TRP A HB3  1 c 
ATOM   2575 H HD1  . TRP A 1 168 ? 0.868   0.184   -19.010 1.000 14.613 0 183  TRP A HD1  1 c 
ATOM   2576 H HE1  . TRP A 1 168 ? 2.181   1.071   -20.844 1.000 14.869 0 183  TRP A HE1  1 c 
ATOM   2577 H HE3  . TRP A 1 168 ? 1.774   4.684   -17.212 1.000 14.928 0 183  TRP A HE3  1 c 
ATOM   2578 H HZ2  . TRP A 1 168 ? 3.442   3.459   -21.462 1.000 14.747 0 183  TRP A HZ2  1 c 
ATOM   2579 H HZ3  . TRP A 1 168 ? 3.021   6.177   -18.500 1.000 15.311 0 183  TRP A HZ3  1 c 
ATOM   2580 H HH2  . TRP A 1 168 ? 3.827   5.572   -20.562 1.000 15.074 0 183  TRP A HH2  1 c 
ATOM   2581 N N    . VAL A 1 169 ? 1.170   -0.955  -16.241 1.000 15.813 0 184  VAL A N    1 ? 
ATOM   2582 C CA   . VAL A 1 169 ? 1.757   -2.263  -16.442 1.000 16.291 0 184  VAL A CA   1 ? 
ATOM   2583 C C    . VAL A 1 169 ? 1.653   -2.751  -17.883 1.000 16.382 0 184  VAL A C    1 ? 
ATOM   2584 O O    . VAL A 1 169 ? 0.771   -2.329  -18.657 1.000 16.615 0 184  VAL A O    1 ? 
ATOM   2585 C CB   . VAL A 1 169 ? 1.220   -3.327  -15.469 1.000 19.357 0 184  VAL A CB   1 ? 
ATOM   2586 C CG1  . VAL A 1 169 ? 1.327   -2.904  -14.015 1.000 20.839 0 184  VAL A CG1  1 ? 
ATOM   2587 C CG2  . VAL A 1 169 ? -0.179  -3.773  -15.813 1.000 20.735 0 184  VAL A CG2  1 ? 
ATOM   2588 H H    . VAL A 1 169 ? 0.301   -0.815  -16.488 1.000 15.978 0 184  VAL A H    1 c 
ATOM   2589 H HA   . VAL A 1 169 ? 2.708   -2.169  -16.250 1.000 16.716 0 184  VAL A HA   1 c 
ATOM   2590 H HB   . VAL A 1 169 ? 1.799   -4.118  -15.574 1.000 19.259 0 184  VAL A HB   1 c 
ATOM   2591 H HG11 . VAL A 1 169 ? 0.768   -2.125  -13.861 1.000 20.349 0 184  VAL A HG11 1 c 
ATOM   2592 H HG12 . VAL A 1 169 ? 2.251   -2.684  -13.808 1.000 20.379 0 184  VAL A HG12 1 c 
ATOM   2593 H HG13 . VAL A 1 169 ? 1.033   -3.632  -13.442 1.000 20.379 0 184  VAL A HG13 1 c 
ATOM   2594 H HG21 . VAL A 1 169 ? -0.539  -4.303  -15.082 1.000 20.283 0 184  VAL A HG21 1 c 
ATOM   2595 H HG22 . VAL A 1 169 ? -0.162  -4.310  -16.623 1.000 20.283 0 184  VAL A HG22 1 c 
ATOM   2596 H HG23 . VAL A 1 169 ? -0.743  -2.993  -15.954 1.000 20.288 0 184  VAL A HG23 1 c 
ATOM   2597 N N    . VAL A 1 170 ? 2.646   -3.553  -18.253 1.000 16.354 0 185  VAL A N    1 ? 
ATOM   2598 C CA   . VAL A 1 170 ? 2.615   -4.335  -19.486 1.000 17.923 0 185  VAL A CA   1 ? 
ATOM   2599 C C    . VAL A 1 170 ? 2.488   -5.811  -19.108 1.000 17.878 0 185  VAL A C    1 ? 
ATOM   2600 O O    . VAL A 1 170 ? 2.858   -6.263  -18.024 1.000 19.138 0 185  VAL A O    1 ? 
ATOM   2601 C CB   . VAL A 1 170 ? 3.817   -4.089  -20.418 1.000 20.976 0 185  VAL A CB   1 ? 
ATOM   2602 C CG1  . VAL A 1 170 ? 3.798   -2.672  -20.970 1.000 21.810 0 185  VAL A CG1  1 ? 
ATOM   2603 C CG2  . VAL A 1 170 ? 5.147   -4.396  -19.745 1.000 22.852 0 185  VAL A CG2  1 ? 
ATOM   2604 H H    . VAL A 1 170 ? 3.378   -3.627  -17.711 1.000 16.768 0 185  VAL A H    1 c 
ATOM   2605 H HA   . VAL A 1 170 ? 1.810   -4.084  -19.973 1.000 18.092 0 185  VAL A HA   1 c 
ATOM   2606 H HB   . VAL A 1 170 ? 3.720   -4.706  -21.181 1.000 20.853 0 185  VAL A HB   1 c 
ATOM   2607 H HG11 . VAL A 1 170 ? 3.710   -2.039  -20.238 1.000 21.486 0 185  VAL A HG11 1 c 
ATOM   2608 H HG12 . VAL A 1 170 ? 3.046   -2.571  -21.576 1.000 21.547 0 185  VAL A HG12 1 c 
ATOM   2609 H HG13 . VAL A 1 170 ? 4.626   -2.499  -21.450 1.000 21.548 0 185  VAL A HG13 1 c 
ATOM   2610 H HG21 . VAL A 1 170 ? 5.873   -4.222  -20.368 1.000 22.241 0 185  VAL A HG21 1 c 
ATOM   2611 H HG22 . VAL A 1 170 ? 5.170   -5.330  -19.478 1.000 22.195 0 185  VAL A HG22 1 c 
ATOM   2612 H HG23 . VAL A 1 170 ? 5.255   -3.832  -18.961 1.000 22.181 0 185  VAL A HG23 1 c 
ATOM   2613 N N    . PHE A 1 171 ? 1.919   -6.605  -20.018 1.000 16.554 0 186  PHE A N    1 ? 
ATOM   2614 C CA   . PHE A 1 171 ? 1.683   -8.018  -19.725 1.000 17.206 0 186  PHE A CA   1 ? 
ATOM   2615 C C    . PHE A 1 171 ? 1.238   -8.703  -21.018 1.000 19.392 0 186  PHE A C    1 ? 
ATOM   2616 O O    . PHE A 1 171 ? 1.077   -8.072  -22.072 1.000 18.394 0 186  PHE A O    1 ? 
ATOM   2617 C CB   . PHE A 1 171 ? 0.543   -8.189  -18.718 1.000 18.164 0 186  PHE A CB   1 ? 
ATOM   2618 C CG   . PHE A 1 171 ? -0.837  -7.780  -19.203 1.000 18.859 0 186  PHE A CG   1 ? 
ATOM   2619 C CD1  . PHE A 1 171 ? -1.223  -6.442  -19.259 1.000 20.528 0 186  PHE A CD1  1 ? 
ATOM   2620 C CD2  . PHE A 1 171 ? -1.742  -8.736  -19.689 1.000 20.039 0 186  PHE A CD2  1 ? 
ATOM   2621 C CE1  . PHE A 1 171 ? -2.479  -6.085  -19.717 1.000 19.370 0 186  PHE A CE1  1 ? 
ATOM   2622 C CE2  . PHE A 1 171 ? -2.991  -8.363  -20.164 1.000 19.981 0 186  PHE A CE2  1 ? 
ATOM   2623 C CZ   . PHE A 1 171 ? -3.357  -7.039  -20.174 1.000 18.989 0 186  PHE A CZ   1 ? 
ATOM   2624 H H    . PHE A 1 171 ? 1.674   -6.268  -20.831 1.000 17.037 0 186  PHE A H    1 c 
ATOM   2625 H HA   . PHE A 1 171 ? 2.512   -8.441  -19.382 1.000 17.647 0 186  PHE A HA   1 c 
ATOM   2626 H HB2  . PHE A 1 171 ? 0.511   -9.133  -18.446 1.000 18.119 0 186  PHE A HB2  1 c 
ATOM   2627 H HB3  . PHE A 1 171 ? 0.758   -7.667  -17.915 1.000 18.106 0 186  PHE A HB3  1 c 
ATOM   2628 H HD1  . PHE A 1 171 ? -0.634  -5.775  -18.943 1.000 19.842 0 186  PHE A HD1  1 c 
ATOM   2629 H HD2  . PHE A 1 171 ? -1.499  -9.648  -19.682 1.000 19.736 0 186  PHE A HD2  1 c 
ATOM   2630 H HE1  . PHE A 1 171 ? -2.728  -5.175  -19.731 1.000 19.526 0 186  PHE A HE1  1 c 
ATOM   2631 H HE2  . PHE A 1 171 ? -3.594  -9.022  -20.468 1.000 19.747 0 186  PHE A HE2  1 c 
ATOM   2632 H HZ   . PHE A 1 171 ? -4.208  -6.786  -20.493 1.000 19.317 0 186  PHE A HZ   1 c 
ATOM   2633 N N    . GLY A 1 172 ? 1.005   -10.009 -20.893 1.000 19.792 0 187  GLY A N    1 ? 
ATOM   2634 C CA   . GLY A 1 172 ? 0.272   -10.764 -21.901 1.000 21.766 0 187  GLY A CA   1 ? 
ATOM   2635 C C    . GLY A 1 172 ? 1.202   -11.241 -23.001 1.000 21.173 0 187  GLY A C    1 ? 
ATOM   2636 O O    . GLY A 1 172 ? 2.439   -11.233 -22.879 1.000 21.964 0 187  GLY A O    1 ? 
ATOM   2637 H H    . GLY A 1 172 ? 1.321   -10.452 -20.159 1.000 20.080 0 187  GLY A H    1 c 
ATOM   2638 H HA2  . GLY A 1 172 ? -0.162  -11.539 -21.474 1.000 21.224 0 187  GLY A HA2  1 c 
ATOM   2639 H HA3  . GLY A 1 172 ? -0.433  -10.192 -22.284 1.000 21.152 0 187  GLY A HA3  1 c 
ATOM   2640 N N    . PRO A 1 173 ? 0.611   -11.696 -24.141 1.000 22.246 0 188  PRO A N    1 ? 
ATOM   2641 C CA   . PRO A 1 173 ? 1.382   -12.261 -25.247 1.000 25.895 0 188  PRO A CA   1 ? 
ATOM   2642 C C    . PRO A 1 173 ? 2.445   -11.286 -25.717 1.000 25.126 0 188  PRO A C    1 ? 
ATOM   2643 O O    . PRO A 1 173 ? 2.151   -10.128 -26.081 1.000 24.927 0 188  PRO A O    1 ? 
ATOM   2644 C CB   . PRO A 1 173 ? 0.318   -12.531 -26.340 1.000 24.071 0 188  PRO A CB   1 ? 
ATOM   2645 C CG   . PRO A 1 173 ? -0.955  -12.676 -25.577 1.000 25.184 0 188  PRO A CG   1 ? 
ATOM   2646 C CD   . PRO A 1 173 ? -0.840  -11.727 -24.393 1.000 24.067 0 188  PRO A CD   1 ? 
ATOM   2647 H HA   . PRO A 1 173 ? 1.796   -13.114 -24.961 1.000 24.700 0 188  PRO A HA   1 c 
ATOM   2648 H HB2  . PRO A 1 173 ? 0.264   -11.778 -26.974 1.000 24.719 0 188  PRO A HB2  1 c 
ATOM   2649 H HB3  . PRO A 1 173 ? 0.526   -13.356 -26.838 1.000 24.717 0 188  PRO A HB3  1 c 
ATOM   2650 H HG2  . PRO A 1 173 ? -1.723  -12.437 -26.137 1.000 24.671 0 188  PRO A HG2  1 c 
ATOM   2651 H HG3  . PRO A 1 173 ? -1.069  -13.599 -25.268 1.000 24.671 0 188  PRO A HG3  1 c 
ATOM   2652 H HD2  . PRO A 1 173 ? -1.181  -10.833 -24.621 1.000 23.869 0 188  PRO A HD2  1 c 
ATOM   2653 H HD3  . PRO A 1 173 ? -1.331  -12.074 -23.615 1.000 23.861 0 188  PRO A HD3  1 c 
ATOM   2654 N N    . ASN A 1 174 ? 3.699   -11.747 -25.675 1.000 25.795 0 189  ASN A N    1 ? 
ATOM   2655 C CA   . ASN A 1 174 ? 4.857   -10.948 -26.054 1.000 29.273 0 189  ASN A CA   1 ? 
ATOM   2656 C C    . ASN A 1 174 ? 5.037   -9.713  -25.180 1.000 27.018 0 189  ASN A C    1 ? 
ATOM   2657 O O    . ASN A 1 174 ? 5.746   -8.785  -25.580 1.000 28.711 0 189  ASN A O    1 ? 
ATOM   2658 C CB   . ASN A 1 174 ? 4.807   -10.433 -27.493 1.000 34.766 0 189  ASN A CB   1 ? 
ATOM   2659 C CG   . ASN A 1 174 ? 4.617   -11.543 -28.494 1.000 42.723 0 189  ASN A CG   1 ? 
ATOM   2660 O OD1  . ASN A 1 174 ? 5.447   -12.460 -28.541 1.000 47.605 0 189  ASN A OD1  1 ? 
ATOM   2661 N ND2  . ASN A 1 174 ? 3.531   -11.499 -29.266 1.000 43.046 0 189  ASN A ND2  1 ? 
ATOM   2662 H H    . ASN A 1 174 ? 3.842   -12.606 -25.396 1.000 26.360 0 189  ASN A H    1 c 
ATOM   2663 H HA   . ASN A 1 174 ? 5.659   -11.511 -25.968 1.000 29.056 0 189  ASN A HA   1 c 
ATOM   2664 H HB2  . ASN A 1 174 ? 4.076   -9.790  -27.582 1.000 34.976 0 189  ASN A HB2  1 c 
ATOM   2665 H HB3  . ASN A 1 174 ? 5.643   -9.967  -27.695 1.000 34.968 0 189  ASN A HB3  1 c 
ATOM   2666 H HD21 . ASN A 1 174 ? 2.941   -10.844 -29.175 1.000 42.810 0 189  ASN A HD21 1 c 
ATOM   2667 H HD22 . ASN A 1 174 ? 3.399   -12.131 -29.875 1.000 42.946 0 189  ASN A HD22 1 c 
ATOM   2668 N N    . GLY A 1 175 ? 4.355   -9.650  -24.037 1.000 26.379 0 190  GLY A N    1 ? 
ATOM   2669 C CA   . GLY A 1 175 ? 4.385   -8.446  -23.228 1.000 25.509 0 190  GLY A CA   1 ? 
ATOM   2670 C C    . GLY A 1 175 ? 3.824   -7.246  -23.991 1.000 24.743 0 190  GLY A C    1 ? 
ATOM   2671 O O    . GLY A 1 175 ? 4.150   -6.120  -23.685 1.000 24.715 0 190  GLY A O    1 ? 
ATOM   2672 H H    . GLY A 1 175 ? 3.884   -10.374 -23.738 1.000 26.307 0 190  GLY A H    1 c 
ATOM   2673 H HA2  . GLY A 1 175 ? 3.856   -8.593  -22.410 1.000 25.543 0 190  GLY A HA2  1 c 
ATOM   2674 H HA3  . GLY A 1 175 ? 5.316   -8.260  -22.960 1.000 25.555 0 190  GLY A HA3  1 c 
ATOM   2675 N N    . GLU A 1 176 ? 2.883   -7.471  -24.915 1.000 22.769 0 191  GLU A N    1 ? 
ATOM   2676 C CA   . GLU A 1 176 ? 2.417   -6.398  -25.783 1.000 21.355 0 191  GLU A CA   1 ? 
ATOM   2677 C C    . GLU A 1 176 ? 1.207   -5.622  -25.262 1.000 20.104 0 191  GLU A C    1 ? 
ATOM   2678 O O    . GLU A 1 176 ? 0.904   -4.552  -25.797 1.000 22.448 0 191  GLU A O    1 ? 
ATOM   2679 C CB   . GLU A 1 176 ? 2.157   -6.907  -27.198 1.000 25.051 0 191  GLU A CB   1 ? 
ATOM   2680 C CG   . GLU A 1 176 ? 0.906   -7.763  -27.366 1.000 32.012 0 191  GLU A CG   1 ? 
ATOM   2681 C CD   . GLU A 1 176 ? 0.960   -8.668  -28.611 1.000 35.206 0 191  GLU A CD   1 ? 
ATOM   2682 O OE1  . GLU A 1 176 ? 1.961   -8.499  -29.376 1.000 34.150 0 191  GLU A OE1  1 ? 
ATOM   2683 O OE2  . GLU A 1 176 ? 0.036   -9.535  -28.793 1.000 29.684 0 191  GLU A OE2  1 ? 
ATOM   2684 H H    . GLU A 1 176 ? 2.515   -8.304  -25.001 1.000 23.006 0 191  GLU A H    1 c 
ATOM   2685 H HA   . GLU A 1 176 ? 3.160   -5.747  -25.869 1.000 22.063 0 191  GLU A HA   1 c 
ATOM   2686 H HB2  . GLU A 1 176 ? 2.087   -6.136  -27.796 1.000 25.568 0 191  GLU A HB2  1 c 
ATOM   2687 H HB3  . GLU A 1 176 ? 2.936   -7.430  -27.482 1.000 25.639 0 191  GLU A HB3  1 c 
ATOM   2688 H HG2  . GLU A 1 176 ? 0.785   -8.323  -26.572 1.000 30.807 0 191  GLU A HG2  1 c 
ATOM   2689 H HG3  . GLU A 1 176 ? 0.123   -7.177  -27.441 1.000 30.844 0 191  GLU A HG3  1 c 
ATOM   2690 N N    . GLN A 1 177 ? 0.465   -6.122  -24.268 1.000 17.544 0 192  GLN A N    1 ? 
ATOM   2691 C CA   . GLN A 1 177 ? -0.690  -5.436  -23.747 1.000 17.316 0 192  GLN A CA   1 ? 
ATOM   2692 C C    . GLN A 1 177 ? -0.266  -4.412  -22.701 1.000 17.287 0 192  GLN A C    1 ? 
ATOM   2693 O O    . GLN A 1 177 ? 0.694   -4.648  -21.959 1.000 18.398 0 192  GLN A O    1 ? 
ATOM   2694 C CB   . GLN A 1 177 ? -1.695  -6.367  -23.066 1.000 17.239 0 192  GLN A CB   1 ? 
ATOM   2695 C CG   . GLN A 1 177 ? -2.374  -7.309  -24.050 1.000 17.446 0 192  GLN A CG   1 ? 
ATOM   2696 C CD   . GLN A 1 177 ? -3.040  -6.547  -25.170 1.000 18.109 0 192  GLN A CD   1 ? 
ATOM   2697 O OE1  . GLN A 1 177 ? -3.784  -5.593  -24.908 1.000 20.221 0 192  GLN A OE1  1 ? 
ATOM   2698 N NE2  . GLN A 1 177 ? -2.730  -6.956  -26.388 1.000 18.976 0 192  GLN A NE2  1 ? 
ATOM   2699 H H    . GLN A 1 177 ? 0.693   -6.928  -23.905 1.000 18.092 0 192  GLN A H    1 c 
ATOM   2700 H HA   . GLN A 1 177 ? -1.137  -4.963  -24.492 1.000 17.390 0 192  GLN A HA   1 c 
ATOM   2701 H HB2  . GLN A 1 177 ? -1.232  -6.894  -22.383 1.000 17.313 0 192  GLN A HB2  1 c 
ATOM   2702 H HB3  . GLN A 1 177 ? -2.378  -5.826  -22.616 1.000 17.325 0 192  GLN A HB3  1 c 
ATOM   2703 H HG2  . GLN A 1 177 ? -1.709  -7.926  -24.423 1.000 17.566 0 192  GLN A HG2  1 c 
ATOM   2704 H HG3  . GLN A 1 177 ? -3.048  -7.841  -23.578 1.000 17.552 0 192  GLN A HG3  1 c 
ATOM   2705 H HE21 . GLN A 1 177 ? -2.264  -7.701  -26.509 1.000 18.684 0 192  GLN A HE21 1 c 
ATOM   2706 H HE22 . GLN A 1 177 ? -2.993  -6.481  -27.089 1.000 18.700 0 192  GLN A HE22 1 c 
ATOM   2707 N N    . THR A 1 178 ? -1.062  -3.337  -22.615 1.000 17.923 0 193  THR A N    1 ? 
ATOM   2708 C CA   . THR A 1 178 ? -0.907  -2.338  -21.569 1.000 17.167 0 193  THR A CA   1 ? 
ATOM   2709 C C    . THR A 1 178 ? -2.175  -2.254  -20.749 1.000 17.644 0 193  THR A C    1 ? 
ATOM   2710 O O    . THR A 1 178 ? -3.315  -2.383  -21.269 1.000 18.158 0 193  THR A O    1 ? 
ATOM   2711 C CB   . THR A 1 178 ? -0.529  -0.961  -22.129 1.000 20.042 0 193  THR A CB   1 ? 
ATOM   2712 O OG1  . THR A 1 178 ? -1.513  -0.517  -23.049 1.000 18.249 0 193  THR A OG1  1 ? 
ATOM   2713 C CG2  . THR A 1 178 ? 0.843   -0.981  -22.770 1.000 22.917 0 193  THR A CG2  1 ? 
ATOM   2714 H H    . THR A 1 178 ? -1.727  -3.223  -23.232 1.000 17.594 0 193  THR A H    1 c 
ATOM   2715 H HA   . THR A 1 178 ? -0.180  -2.631  -20.980 1.000 17.878 0 193  THR A HA   1 c 
ATOM   2716 H HB   . THR A 1 178 ? -0.495  -0.323  -21.377 1.000 19.608 0 193  THR A HB   1 c 
ATOM   2717 H HG1  . THR A 1 178 ? -1.575  -1.079  -23.702 0.000 18.240 0 193  THR A HG1  1 c 
ATOM   2718 H HG21 . THR A 1 178 ? 0.984   -0.154  -23.262 1.000 22.107 0 193  THR A HG21 1 c 
ATOM   2719 H HG22 . THR A 1 178 ? 0.910   -1.735  -23.379 1.000 22.088 0 193  THR A HG22 1 c 
ATOM   2720 H HG23 . THR A 1 178 ? 1.521   -1.063  -22.079 1.000 22.048 0 193  THR A HG23 1 c 
ATOM   2721 N N    . ALA A 1 179 ? -1.997  -2.003  -19.445 1.000 16.566 0 194  ALA A N    1 ? 
ATOM   2722 C CA   . ALA A 1 179 ? -3.127  -1.696  -18.606 1.000 16.648 0 194  ALA A CA   1 ? 
ATOM   2723 C C    . ALA A 1 179 ? -2.814  -0.586  -17.611 1.000 17.326 0 194  ALA A C    1 ? 
ATOM   2724 O O    . ALA A 1 179 ? -1.832  -0.694  -16.889 1.000 17.559 0 194  ALA A O    1 ? 
ATOM   2725 C CB   . ALA A 1 179 ? -3.611  -2.904  -17.829 1.000 18.120 0 194  ALA A CB   1 ? 
ATOM   2726 H H    . ALA A 1 179 ? -1.159  -2.026  -19.080 1.000 16.849 0 194  ALA A H    1 c 
ATOM   2727 H HA   . ALA A 1 179 ? -3.866  -1.381  -19.191 1.000 17.049 0 194  ALA A HA   1 c 
ATOM   2728 H HB1  . ALA A 1 179 ? -3.900  -3.596  -18.447 1.000 17.684 0 194  ALA A HB1  1 c 
ATOM   2729 H HB2  . ALA A 1 179 ? -2.889  -3.248  -17.277 1.000 17.674 0 194  ALA A HB2  1 c 
ATOM   2730 H HB3  . ALA A 1 179 ? -4.357  -2.650  -17.261 1.000 17.673 0 194  ALA A HB3  1 c 
ATOM   2731 N N    . GLU A 1 180 ? -3.745  0.354   -17.496 1.000 17.347 0 195  GLU A N    1 ? 
ATOM   2732 C CA   . GLU A 1 180 ? -3.783  1.352   -16.434 1.000 16.772 0 195  GLU A CA   1 ? 
ATOM   2733 C C    . GLU A 1 180 ? -4.119  0.621   -15.137 1.000 18.210 0 195  GLU A C    1 ? 
ATOM   2734 O O    . GLU A 1 180 ? -5.097  -0.128  -15.075 1.000 20.930 0 195  GLU A O    1 ? 
ATOM   2735 C CB   . GLU A 1 180 ? -4.797  2.457   -16.730 1.000 17.915 0 195  GLU A CB   1 ? 
ATOM   2736 C CG   . GLU A 1 180 ? -4.436  3.314   -17.935 1.000 17.231 0 195  GLU A CG   1 ? 
ATOM   2737 C CD   . GLU A 1 180 ? -3.440  4.415   -17.699 1.000 18.445 0 195  GLU A CD   1 ? 
ATOM   2738 O OE1  . GLU A 1 180 ? -2.922  4.508   -16.577 1.000 19.066 0 195  GLU A OE1  1 ? 
ATOM   2739 O OE2  . GLU A 1 180 ? -3.247  5.228   -18.629 1.000 18.156 0 195  GLU A OE2  1 ? 
ATOM   2740 H H    . GLU A 1 180 ? -4.406  0.380   -18.126 1.000 17.209 0 195  GLU A H    1 c 
ATOM   2741 H HA   . GLU A 1 180 ? -2.882  1.754   -16.354 1.000 17.340 0 195  GLU A HA   1 c 
ATOM   2742 H HB2  . GLU A 1 180 ? -5.668  2.042   -16.890 1.000 17.540 0 195  GLU A HB2  1 c 
ATOM   2743 H HB3  . GLU A 1 180 ? -4.882  3.029   -15.938 1.000 17.510 0 195  GLU A HB3  1 c 
ATOM   2744 H HG2  . GLU A 1 180 ? -4.081  2.730   -18.639 1.000 17.660 0 195  GLU A HG2  1 c 
ATOM   2745 H HG3  . GLU A 1 180 ? -5.257  3.718   -18.287 1.000 17.661 0 195  GLU A HG3  1 c 
ATOM   2746 N N    . VAL A 1 181 ? -3.392  0.944   -14.063 1.000 17.503 0 196  VAL A N    1 ? 
ATOM   2747 C CA   . VAL A 1 181 ? -3.638  0.327   -12.754 1.000 17.211 0 196  VAL A CA   1 ? 
ATOM   2748 C C    . VAL A 1 181 ? -3.643  1.350   -11.618 1.000 17.392 0 196  VAL A C    1 ? 
ATOM   2749 O O    . VAL A 1 181 ? -3.926  0.968   -10.453 1.000 19.828 0 196  VAL A O    1 ? 
ATOM   2750 C CB   . VAL A 1 181 ? -2.595  -0.757  -12.464 1.000 18.326 0 196  VAL A CB   1 ? 
ATOM   2751 C CG1  . VAL A 1 181 ? -2.591  -1.906  -13.479 1.000 19.247 0 196  VAL A CG1  1 ? 
ATOM   2752 C CG2  . VAL A 1 181 ? -1.156  -0.201  -12.377 1.000 18.712 0 196  VAL A CG2  1 ? 
ATOM   2753 H H    . VAL A 1 181 ? -2.706  1.541   -14.149 1.000 17.585 0 196  VAL A H    1 c 
ATOM   2754 H HA   . VAL A 1 181 ? -4.517  -0.099  -12.778 1.000 17.525 0 196  VAL A HA   1 c 
ATOM   2755 H HB   . VAL A 1 181 ? -2.817  -1.142  -11.584 1.000 18.350 0 196  VAL A HB   1 c 
ATOM   2756 H HG11 . VAL A 1 181 ? -2.338  -1.566  -14.354 1.000 18.976 0 196  VAL A HG11 1 c 
ATOM   2757 H HG12 . VAL A 1 181 ? -3.479  -2.298  -13.529 1.000 19.035 0 196  VAL A HG12 1 c 
ATOM   2758 H HG13 . VAL A 1 181 ? -1.954  -2.584  -13.200 1.000 18.983 0 196  VAL A HG13 1 c 
ATOM   2759 H HG21 . VAL A 1 181 ? -0.532  -0.936  -12.257 1.000 18.612 0 196  VAL A HG21 1 c 
ATOM   2760 H HG22 . VAL A 1 181 ? -1.086  0.408   -11.624 1.000 18.593 0 196  VAL A HG22 1 c 
ATOM   2761 H HG23 . VAL A 1 181 ? -0.941  0.273   -13.198 1.000 18.588 0 196  VAL A HG23 1 c 
ATOM   2762 N N    . THR A 1 182 ? -3.254  2.607   -11.866 1.000 16.386 0 197  THR A N    1 ? 
ATOM   2763 C CA   . THR A 1 182 ? -3.248  3.632   -10.845 1.000 16.829 0 197  THR A CA   1 ? 
ATOM   2764 C C    . THR A 1 182 ? -3.829  4.927   -11.416 1.000 18.606 0 197  THR A C    1 ? 
ATOM   2765 O O    . THR A 1 182 ? -4.208  5.019   -12.603 1.000 20.185 0 197  THR A O    1 ? 
ATOM   2766 C CB   . THR A 1 182 ? -1.832  3.771   -10.282 1.000 17.519 0 197  THR A CB   1 ? 
ATOM   2767 O OG1  . THR A 1 182 ? -1.897  4.578   -9.102  1.000 17.152 0 197  THR A OG1  1 ? 
ATOM   2768 C CG2  . THR A 1 182 ? -0.891  4.389   -11.302 1.000 19.300 0 197  THR A CG2  1 ? 
ATOM   2769 H H    . THR A 1 182 ? -2.984  2.835   -12.708 1.000 16.764 0 197  THR A H    1 c 
ATOM   2770 H HA   . THR A 1 182 ? -3.833  3.336   -10.116 1.000 17.243 0 197  THR A HA   1 c 
ATOM   2771 H HB   . THR A 1 182 ? -1.491  2.877   -10.042 1.000 17.632 0 197  THR A HB   1 c 
ATOM   2772 H HG1  . THR A 1 182 ? -2.214  5.356   -9.300  0.000 17.180 0 197  THR A HG1  1 c 
ATOM   2773 H HG21 . THR A 1 182 ? 0.024   4.318   -10.984 1.000 18.729 0 197  THR A HG21 1 c 
ATOM   2774 H HG22 . THR A 1 182 ? -1.116  5.325   -11.429 1.000 18.742 0 197  THR A HG22 1 c 
ATOM   2775 H HG23 . THR A 1 182 ? -0.974  3.919   -12.148 1.000 18.705 0 197  THR A HG23 1 c 
ATOM   2776 N N    . TRP A 1 183 ? -3.913  5.949   -10.571 1.000 18.141 0 198  TRP A N    1 ? 
ATOM   2777 C CA   . TRP A 1 183 ? -4.376  7.270   -10.934 1.000 18.309 0 198  TRP A CA   1 ? 
ATOM   2778 C C    . TRP A 1 183 ? -3.221  8.130   -11.450 1.000 20.048 0 198  TRP A C    1 ? 
ATOM   2779 O O    . TRP A 1 183 ? -2.065  7.808   -11.232 1.000 19.068 0 198  TRP A O    1 ? 
ATOM   2780 C CB   . TRP A 1 183 ? -5.093  7.971   -9.783  1.000 20.497 0 198  TRP A CB   1 ? 
ATOM   2781 C CG   . TRP A 1 183 ? -4.196  8.478   -8.688  1.000 21.365 0 198  TRP A CG   1 ? 
ATOM   2782 C CD1  . TRP A 1 183 ? -3.692  9.730   -8.598  1.000 26.463 0 198  TRP A CD1  1 ? 
ATOM   2783 C CD2  . TRP A 1 183 ? -3.749  7.755   -7.523  1.000 22.095 0 198  TRP A CD2  1 ? 
ATOM   2784 N NE1  . TRP A 1 183 ? -2.939  9.850   -7.464  1.000 26.166 0 198  TRP A NE1  1 ? 
ATOM   2785 C CE2  . TRP A 1 183 ? -2.958  8.668   -6.788  1.000 23.231 0 198  TRP A CE2  1 ? 
ATOM   2786 C CE3  . TRP A 1 183 ? -3.938  6.463   -7.041  1.000 22.956 0 198  TRP A CE3  1 ? 
ATOM   2787 C CZ2  . TRP A 1 183 ? -2.351  8.282   -5.600  1.000 24.533 0 198  TRP A CZ2  1 ? 
ATOM   2788 C CZ3  . TRP A 1 183 ? -3.339  6.089   -5.853  1.000 26.702 0 198  TRP A CZ3  1 ? 
ATOM   2789 C CH2  . TRP A 1 183 ? -2.572  7.007   -5.158  1.000 21.388 0 198  TRP A CH2  1 ? 
ATOM   2790 H H    . TRP A 1 183 ? -3.659  5.810   -9.705  1.000 18.378 0 198  TRP A H    1 c 
ATOM   2791 H HA   . TRP A 1 183 ? -5.033  7.167   -11.674 1.000 18.983 0 198  TRP A HA   1 c 
ATOM   2792 H HB2  . TRP A 1 183 ? -5.600  8.726   -10.150 1.000 20.169 0 198  TRP A HB2  1 c 
ATOM   2793 H HB3  . TRP A 1 183 ? -5.740  7.344   -9.395  1.000 20.169 0 198  TRP A HB3  1 c 
ATOM   2794 H HD1  . TRP A 1 183 ? -3.825  10.421  -9.227  1.000 25.161 0 198  TRP A HD1  1 c 
ATOM   2795 H HE1  . TRP A 1 183 ? -2.512  10.570  -7.216  1.000 25.448 0 198  TRP A HE1  1 c 
ATOM   2796 H HE3  . TRP A 1 183 ? -4.460  5.852   -7.522  1.000 23.571 0 198  TRP A HE3  1 c 
ATOM   2797 H HZ2  . TRP A 1 183 ? -1.830  8.887   -5.102  1.000 23.479 0 198  TRP A HZ2  1 c 
ATOM   2798 H HZ3  . TRP A 1 183 ? -3.458  5.218   -5.515  1.000 24.381 0 198  TRP A HZ3  1 c 
ATOM   2799 H HH2  . TRP A 1 183 ? -2.171  6.737   -4.353  1.000 23.236 0 198  TRP A HH2  1 c 
ATOM   2800 N N    . HIS A 1 184 ? -3.579  9.215   -12.136 1.000 19.777 0 199  HIS A N    1 ? 
ATOM   2801 C CA   . HIS A 1 184 ? -2.601  10.211  -12.525 1.000 19.994 0 199  HIS A CA   1 ? 
ATOM   2802 C C    . HIS A 1 184 ? -3.061  11.590  -12.106 1.000 23.176 0 199  HIS A C    1 ? 
ATOM   2803 O O    . HIS A 1 184 ? -4.164  11.971  -12.429 1.000 25.501 0 199  HIS A O    1 ? 
ATOM   2804 C CB   . HIS A 1 184 ? -2.305  10.138  -14.025 1.000 18.563 0 199  HIS A CB   1 ? 
ATOM   2805 C CG   . HIS A 1 184 ? -1.376  11.242  -14.364 1.000 19.756 0 199  HIS A CG   1 ? 
ATOM   2806 N ND1  . HIS A 1 184 ? -1.739  12.398  -15.022 1.000 20.986 0 199  HIS A ND1  1 ? 
ATOM   2807 C CD2  . HIS A 1 184 ? -0.044  11.292  -14.184 1.000 19.734 0 199  HIS A CD2  1 ? 
ATOM   2808 C CE1  . HIS A 1 184 ? -0.626  13.152  -15.178 1.000 20.784 0 199  HIS A CE1  1 ? 
ATOM   2809 N NE2  . HIS A 1 184 ? 0.400   12.530  -14.631 1.000 19.249 0 199  HIS A NE2  1 ? 
ATOM   2810 H H    . HIS A 1 184 ? -4.454  9.339   -12.369 1.000 19.872 0 199  HIS A H    1 c 
ATOM   2811 H HA   . HIS A 1 184 ? -1.760  10.012  -12.044 1.000 20.293 0 199  HIS A HA   1 c 
ATOM   2812 H HB2  . HIS A 1 184 ? -1.886  9.276   -14.234 1.000 19.147 0 199  HIS A HB2  1 c 
ATOM   2813 H HB3  . HIS A 1 184 ? -3.142  10.242  -14.529 1.000 19.150 0 199  HIS A HB3  1 c 
ATOM   2814 H HD1  . HIS A 1 184 ? -2.553  12.594  -15.298 0.000 20.940 0 199  HIS A HD1  1 c 
ATOM   2815 H HD2  . HIS A 1 184 ? 0.479   10.655  -13.739 1.000 19.615 0 199  HIS A HD2  1 c 
ATOM   2816 H HE1  . HIS A 1 184 ? -0.604  14.006  -15.572 1.000 20.433 0 199  HIS A HE1  1 c 
ATOM   2817 H HE2  . HIS A 1 184 ? 1.222   12.827  -14.613 0.000 19.280 0 199  HIS A HE2  1 c 
ATOM   2818 N N    . GLY A 1 185 ? -2.168  12.339  -11.470 1.000 26.190 0 200  GLY A N    1 ? 
ATOM   2819 C CA   . GLY A 1 185 ? -2.442  13.727  -11.155 1.000 31.500 0 200  GLY A CA   1 ? 
ATOM   2820 C C    . GLY A 1 185 ? -3.506  13.785  -10.071 1.000 38.506 0 200  GLY A C    1 ? 
ATOM   2821 O O    . GLY A 1 185 ? -3.400  13.041  -9.091  1.000 43.490 0 200  GLY A O    1 ? 
ATOM   2822 H H    . GLY A 1 185 ? -1.364  11.980  -11.224 1.000 26.408 0 200  GLY A H    1 c 
ATOM   2823 H HA2  . GLY A 1 185 ? -1.616  14.164  -10.842 1.000 31.529 0 200  GLY A HA2  1 c 
ATOM   2824 H HA3  . GLY A 1 185 ? -2.755  14.195  -11.965 1.000 31.538 0 200  GLY A HA3  1 c 
ATOM   2825 N N    . LYS A 1 186 ? -4.534  14.618  -10.289 1.000 39.019 0 201  LYS A N    1 ? 
ATOM   2826 C CA   . LYS A 1 186 ? -5.593  14.814  -9.309  1.000 48.415 0 201  LYS A CA   1 ? 
ATOM   2827 C C    . LYS A 1 186 ? -6.517  13.593  -9.215  1.000 61.919 0 201  LYS A C    1 ? 
ATOM   2828 O O    . LYS A 1 186 ? -7.386  13.557  -8.343  1.000 72.947 0 201  LYS A O    1 ? 
ATOM   2829 C CB   . LYS A 1 186 ? -6.412  16.057  -9.682  1.000 46.920 0 201  LYS A CB   1 ? 
ATOM   2830 H H    . LYS A 1 186 ? -4.576  15.078  -11.077 1.000 40.716 0 201  LYS A H    1 c 
ATOM   2831 H HA   . LYS A 1 186 ? -5.173  14.962  -8.424  1.000 48.191 0 201  LYS A HA   1 c 
ATOM   2832 H HB2  . LYS A 1 186 ? -7.029  15.823  -10.407 1.000 47.624 0 201  LYS A HB2  1 c 
ATOM   2833 H HB3  . LYS A 1 186 ? -7.144  16.159  -9.020  0.000 46.320 0 201  LYS A HB3  1 c 
ATOM   2834 N N    . GLY A 1 187 ? -6.332  12.589  -10.091 1.000 61.504 0 202  GLY A N    1 ? 
ATOM   2835 C CA   . GLY A 1 187 ? -7.289  11.500  -10.232 1.000 62.385 0 202  GLY A CA   1 ? 
ATOM   2836 C C    . GLY A 1 187 ? -8.460  11.944  -11.102 1.000 68.282 0 202  GLY A C    1 ? 
ATOM   2837 O O    . GLY A 1 187 ? -9.541  11.360  -11.032 1.000 66.642 0 202  GLY A O    1 ? 
ATOM   2838 H H    . GLY A 1 187 ? -5.587  12.581  -10.618 1.000 61.361 0 202  GLY A H    1 c 
ATOM   2839 H HA2  . GLY A 1 187 ? -6.842  10.724  -10.645 1.000 63.446 0 202  GLY A HA2  1 c 
ATOM   2840 H HA3  . GLY A 1 187 ? -7.615  11.230  -9.342  1.000 63.480 0 202  GLY A HA3  1 c 
ATOM   2841 N N    . ASN A 1 188 ? -8.176  12.956  -11.939 1.000 77.256 0 203  ASN A N    1 ? 
ATOM   2842 C CA   . ASN A 1 188 ? -9.152  13.687  -12.729 1.000 80.193 0 203  ASN A CA   1 ? 
ATOM   2843 C C    . ASN A 1 188 ? -9.882  12.723  -13.665 1.000 84.597 0 203  ASN A C    1 ? 
ATOM   2844 O O    . ASN A 1 188 ? -11.110 12.662  -13.636 1.000 86.949 0 203  ASN A O    1 ? 
ATOM   2845 C CB   . ASN A 1 188 ? -8.518  14.901  -13.417 1.000 80.010 0 203  ASN A CB   1 ? 
ATOM   2846 C CG   . ASN A 1 188 ? -7.022  14.790  -13.636 1.000 79.973 0 203  ASN A CG   1 ? 
ATOM   2847 O OD1  . ASN A 1 188 ? -6.240  15.409  -12.905 1.000 71.226 0 203  ASN A OD1  1 ? 
ATOM   2848 N ND2  . ASN A 1 188 ? -6.589  14.023  -14.626 1.000 78.637 0 203  ASN A ND2  1 ? 
ATOM   2849 H H    . ASN A 1 188 ? -7.299  13.193  -12.027 1.000 75.293 0 203  ASN A H    1 c 
ATOM   2850 H HA   . ASN A 1 188 ? -9.822  14.041  -12.102 1.000 80.411 0 203  ASN A HA   1 c 
ATOM   2851 H HB2  . ASN A 1 188 ? -8.952  15.032  -14.284 1.000 80.068 0 203  ASN A HB2  1 c 
ATOM   2852 H HB3  . ASN A 1 188 ? -8.697  15.695  -12.875 1.000 80.048 0 203  ASN A HB3  1 c 
ATOM   2853 H HD21 . ASN A 1 188 ? -7.051  13.974  -15.381 1.000 79.035 0 203  ASN A HD21 1 c 
ATOM   2854 H HD22 . ASN A 1 188 ? -5.838  13.561  -14.532 1.000 79.043 0 203  ASN A HD22 1 c 
ATOM   2855 N N    . GLU A 1 189 ? -9.128  11.972  -14.481 1.000 77.579 0 204  GLU A N    1 ? 
ATOM   2856 C CA   . GLU A 1 189 ? -9.697  10.950  -15.348 1.000 71.522 0 204  GLU A CA   1 ? 
ATOM   2857 C C    . GLU A 1 189 ? -9.665  9.622   -14.597 1.000 77.878 0 204  GLU A C    1 ? 
ATOM   2858 O O    . GLU A 1 189 ? -9.747  9.605   -13.374 1.000 90.039 0 204  GLU A O    1 ? 
ATOM   2859 C CB   . GLU A 1 189 ? -8.923  10.904  -16.666 1.000 66.077 0 204  GLU A CB   1 ? 
ATOM   2860 H H    . GLU A 1 189 ? -8.223  12.098  -14.491 1.000 77.705 0 204  GLU A H    1 c 
ATOM   2861 H HA   . GLU A 1 189 ? -10.640 11.185  -15.540 1.000 72.879 0 204  GLU A HA   1 c 
ATOM   2862 H HB2  . GLU A 1 189 ? -8.004  10.621  -16.480 1.000 67.420 0 204  GLU A HB2  1 c 
ATOM   2863 H HB3  . GLU A 1 189 ? -9.332  10.137  -17.198 0.000 65.810 0 204  GLU A HB3  1 c 
ATOM   2864 N N    . ASP A 1 190 ? -9.561  8.508   -15.324 1.000 85.422 0 205  ASP A N    1 ? 
ATOM   2865 C CA   . ASP A 1 190 ? -9.089  7.265   -14.727 1.000 85.579 0 205  ASP A CA   1 ? 
ATOM   2866 C C    . ASP A 1 190 ? -8.542  6.369   -15.837 1.000 73.304 0 205  ASP A C    1 ? 
ATOM   2867 O O    . ASP A 1 190 ? -7.323  6.327   -16.067 1.000 68.435 0 205  ASP A O    1 ? 
ATOM   2868 C CB   . ASP A 1 190 ? -10.152 6.609   -13.851 1.000 85.891 0 205  ASP A CB   1 ? 
ATOM   2869 C CG   . ASP A 1 190 ? -11.538 6.512   -14.472 1.000 89.161 0 205  ASP A CG   1 ? 
ATOM   2870 O OD1  . ASP A 1 190 ? -11.932 7.490   -15.145 1.000 99.816 0 205  ASP A OD1  1 ? 
ATOM   2871 O OD2  . ASP A 1 190 ? -12.208 5.468   -14.277 1.000 72.561 0 205  ASP A OD2  1 ? 
ATOM   2872 H H    . ASP A 1 190 ? -9.805  8.513   -16.204 1.000 83.306 0 205  ASP A H    1 c 
ATOM   2873 H HA   . ASP A 1 190 ? -8.340  7.486   -14.127 1.000 83.205 0 205  ASP A HA   1 c 
ATOM   2874 H HB2  . ASP A 1 190 ? -9.855  5.701   -13.633 1.000 86.470 0 205  ASP A HB2  1 c 
ATOM   2875 H HB3  . ASP A 1 190 ? -10.227 7.107   -13.011 1.000 86.561 0 205  ASP A HB3  1 c 
ATOM   2876 N N    . ARG A 1 191 ? -9.490  5.728   -16.544 1.000 58.043 0 206  ARG A N    1 ? 
ATOM   2877 C CA   . ARG A 1 191 ? -9.223  4.699   -17.535 1.000 40.505 0 206  ARG A CA   1 ? 
ATOM   2878 C C    . ARG A 1 191 ? -8.598  3.466   -16.878 1.000 35.734 0 206  ARG A C    1 ? 
ATOM   2879 O O    . ARG A 1 191 ? -7.853  2.740   -17.531 1.000 26.087 0 206  ARG A O    1 ? 
ATOM   2880 C CB   . ARG A 1 191 ? -8.342  5.247   -18.662 1.000 42.652 0 206  ARG A CB   1 ? 
ATOM   2881 C CG   . ARG A 1 191 ? -8.874  6.561   -19.216 1.000 46.046 0 206  ARG A CG   1 ? 
ATOM   2882 C CD   . ARG A 1 191 ? -8.145  7.006   -20.471 1.000 47.937 0 206  ARG A CD   1 ? 
ATOM   2883 N NE   . ARG A 1 191 ? -6.768  7.422   -20.186 1.000 38.433 0 206  ARG A NE   1 ? 
ATOM   2884 C CZ   . ARG A 1 191 ? -6.389  8.573   -19.644 1.000 45.183 0 206  ARG A CZ   1 ? 
ATOM   2885 N NH1  . ARG A 1 191 ? -7.268  9.450   -19.165 1.000 51.235 0 206  ARG A NH1  1 ? 
ATOM   2886 N NH2  . ARG A 1 191 ? -5.106  8.852   -19.567 1.000 39.951 0 206  ARG A NH2  1 ? 
ATOM   2887 H H    . ARG A 1 191 ? -10.360 5.972   -16.416 1.000 56.994 0 206  ARG A H    1 c 
ATOM   2888 H HA   . ARG A 1 191 ? -10.090 4.428   -17.932 1.000 42.898 0 206  ARG A HA   1 c 
ATOM   2889 H HB2  . ARG A 1 191 ? -7.430  5.384   -18.327 1.000 43.083 0 206  ARG A HB2  1 c 
ATOM   2890 H HB3  . ARG A 1 191 ? -8.301  4.588   -19.387 1.000 42.683 0 206  ARG A HB3  1 c 
ATOM   2891 H HG2  . ARG A 1 191 ? -9.829  6.461   -19.422 1.000 45.706 0 206  ARG A HG2  1 c 
ATOM   2892 H HG3  . ARG A 1 191 ? -8.785  7.261   -18.533 1.000 45.857 0 206  ARG A HG3  1 c 
ATOM   2893 H HD2  . ARG A 1 191 ? -8.131  6.267   -21.113 1.000 45.087 0 206  ARG A HD2  1 c 
ATOM   2894 H HD3  . ARG A 1 191 ? -8.629  7.751   -20.881 1.000 45.111 0 206  ARG A HD3  1 c 
ATOM   2895 H HE   . ARG A 1 191 ? -6.136  6.858   -20.391 1.000 42.016 0 206  ARG A HE   1 c 
ATOM   2896 H HH11 . ARG A 1 191 ? -7.011  10.033  -18.551 1.000 49.334 0 206  ARG A HH11 1 c 
ATOM   2897 H HH12 . ARG A 1 191 ? -8.101  9.457   -19.460 1.000 49.256 0 206  ARG A HH12 1 c 
ATOM   2898 H HH21 . ARG A 1 191 ? -4.841  9.604   -19.184 1.000 41.618 0 206  ARG A HH21 1 c 
ATOM   2899 H HH22 . ARG A 1 191 ? -4.509  8.290   -19.898 1.000 41.504 0 206  ARG A HH22 1 c 
ATOM   2900 N N    . ARG A 1 192 ? -8.892  3.206   -15.589 1.000 33.485 0 207  ARG A N    1 ? 
ATOM   2901 C CA   . ARG A 1 192 ? -8.289  2.065   -14.928 1.000 31.787 0 207  ARG A CA   1 ? 
ATOM   2902 C C    . ARG A 1 192 ? -8.740  0.816   -15.687 1.000 26.705 0 207  ARG A C    1 ? 
ATOM   2903 O O    . ARG A 1 192 ? -9.918  0.714   -16.038 1.000 30.667 0 207  ARG A O    1 ? 
ATOM   2904 C CB   . ARG A 1 192 ? -8.613  1.989   -13.420 1.000 40.490 0 207  ARG A CB   1 ? 
ATOM   2905 C CG   . ARG A 1 192 ? -7.470  1.368   -12.624 1.000 40.581 0 207  ARG A CG   1 ? 
ATOM   2906 C CD   . ARG A 1 192 ? -7.360  1.807   -11.151 1.000 44.135 0 207  ARG A CD   1 ? 
ATOM   2907 N NE   . ARG A 1 192 ? -8.598  1.473   -10.440 1.000 42.402 0 207  ARG A NE   1 ? 
ATOM   2908 C CZ   . ARG A 1 192 ? -9.000  0.285   -10.051 1.000 45.391 0 207  ARG A CZ   1 ? 
ATOM   2909 N NH1  . ARG A 1 192 ? -8.161  -0.717  -9.825  1.000 37.901 0 207  ARG A NH1  1 ? 
ATOM   2910 N NH2  . ARG A 1 192 ? -10.274 0.136   -9.731  1.000 56.887 0 207  ARG A NH2  1 ? 
ATOM   2911 H H    . ARG A 1 192 ? -9.478  3.735   -15.129 1.000 33.975 0 207  ARG A H    1 c 
ATOM   2912 H HA   . ARG A 1 192 ? -7.307  2.147   -15.025 1.000 32.480 0 207  ARG A HA   1 c 
ATOM   2913 H HB2  . ARG A 1 192 ? -8.787  2.892   -13.080 1.000 38.318 0 207  ARG A HB2  1 c 
ATOM   2914 H HB3  . ARG A 1 192 ? -9.425  1.453   -13.288 1.000 38.281 0 207  ARG A HB3  1 c 
ATOM   2915 H HG2  . ARG A 1 192 ? -7.568  0.391   -12.649 1.000 41.309 0 207  ARG A HG2  1 c 
ATOM   2916 H HG3  . ARG A 1 192 ? -6.623  1.579   -13.073 1.000 41.195 0 207  ARG A HG3  1 c 
ATOM   2917 H HD2  . ARG A 1 192 ? -6.606  1.350   -10.729 1.000 42.552 0 207  ARG A HD2  1 c 
ATOM   2918 H HD3  . ARG A 1 192 ? -7.205  2.773   -11.102 1.000 42.728 0 207  ARG A HD3  1 c 
ATOM   2919 H HE   . ARG A 1 192 ? -9.127  2.138   -10.249 1.000 43.656 0 207  ARG A HE   1 c 
ATOM   2920 H HH11 . ARG A 1 192 ? -8.438  -1.550  -9.925  1.000 40.140 0 207  ARG A HH11 1 c 
ATOM   2921 H HH12 . ARG A 1 192 ? -7.330  -0.551  -9.575  1.000 40.020 0 207  ARG A HH12 1 c 
ATOM   2922 H HH21 . ARG A 1 192 ? -10.530 -0.578  -9.274  1.000 52.764 0 207  ARG A HH21 1 c 
ATOM   2923 H HH22 . ARG A 1 192 ? -10.868 0.745   -9.975  1.000 52.819 0 207  ARG A HH22 1 c 
ATOM   2924 N N    . GLY A 1 193 ? -7.780  -0.066  -15.999 1.000 25.706 0 208  GLY A N    1 ? 
ATOM   2925 C CA   . GLY A 1 193 ? -8.037  -1.287  -16.719 1.000 24.287 0 208  GLY A CA   1 ? 
ATOM   2926 C C    . GLY A 1 193 ? -7.891  -1.186  -18.231 1.000 24.983 0 208  GLY A C    1 ? 
ATOM   2927 O O    . GLY A 1 193 ? -7.825  -2.248  -18.879 1.000 27.037 0 208  GLY A O    1 ? 
ATOM   2928 H H    . GLY A 1 193 ? -6.920  0.111   -15.744 1.000 25.652 0 208  GLY A H    1 c 
ATOM   2929 H HA2  . GLY A 1 193 ? -7.418  -1.978  -16.386 1.000 24.783 0 208  GLY A HA2  1 c 
ATOM   2930 H HA3  . GLY A 1 193 ? -8.952  -1.589  -16.507 1.000 24.816 0 208  GLY A HA3  1 c 
ATOM   2931 N N    . GLN A 1 194 ? -7.873  0.038   -18.780 1.000 23.717 0 209  GLN A N    1 ? 
ATOM   2932 C CA   . GLN A 1 194 ? -7.775  0.260   -20.220 1.000 21.255 0 209  GLN A CA   1 ? 
ATOM   2933 C C    . GLN A 1 194 ? -6.319  0.289   -20.666 1.000 19.879 0 209  GLN A C    1 ? 
ATOM   2934 O O    . GLN A 1 194 ? -5.385  0.363   -19.854 1.000 20.388 0 209  GLN A O    1 ? 
ATOM   2935 C CB   . GLN A 1 194 ? -8.423  1.607   -20.517 1.000 25.897 0 209  GLN A CB   1 ? 
ATOM   2936 C CG   . GLN A 1 194 ? -9.906  1.624   -20.164 1.000 30.492 0 209  GLN A CG   1 ? 
ATOM   2937 C CD   . GLN A 1 194 ? -10.586 2.903   -20.581 1.000 37.892 0 209  GLN A CD   1 ? 
ATOM   2938 O OE1  . GLN A 1 194 ? -10.078 3.687   -21.403 1.000 42.336 0 209  GLN A OE1  1 ? 
ATOM   2939 N NE2  . GLN A 1 194 ? -11.761 3.107   -20.013 1.000 43.873 0 209  GLN A NE2  1 ? 
ATOM   2940 H H    . GLN A 1 194 ? -7.919  0.768   -18.233 1.000 23.499 0 209  GLN A H    1 c 
ATOM   2941 H HA   . GLN A 1 194 ? -8.256  -0.465  -20.695 1.000 22.267 0 209  GLN A HA   1 c 
ATOM   2942 H HB2  . GLN A 1 194 ? -7.961  2.306   -20.010 1.000 25.766 0 209  GLN A HB2  1 c 
ATOM   2943 H HB3  . GLN A 1 194 ? -8.317  1.806   -21.470 1.000 25.707 0 209  GLN A HB3  1 c 
ATOM   2944 H HG2  . GLN A 1 194 ? -10.352 0.870   -20.603 1.000 30.903 0 209  GLN A HG2  1 c 
ATOM   2945 H HG3  . GLN A 1 194 ? -10.010 1.512   -19.195 1.000 30.920 0 209  GLN A HG3  1 c 
ATOM   2946 H HE21 . GLN A 1 194 ? -12.131 2.475   -19.511 1.000 41.732 0 209  GLN A HE21 1 c 
ATOM   2947 H HE22 . GLN A 1 194 ? -12.181 3.879   -20.134 1.000 41.891 0 209  GLN A HE22 1 c 
ATOM   2948 N N    . THR A 1 195 ? -6.125  0.294   -21.990 1.000 19.447 0 210  THR A N    1 ? 
ATOM   2949 C CA   . THR A 1 195 ? -4.801  0.431   -22.596 1.000 17.474 0 210  THR A CA   1 ? 
ATOM   2950 C C    . THR A 1 195 ? -4.381  1.892   -22.509 1.000 15.699 0 210  THR A C    1 ? 
ATOM   2951 O O    . THR A 1 195 ? -5.152  2.801   -22.189 1.000 18.066 0 210  THR A O    1 ? 
ATOM   2952 C CB   . THR A 1 195 ? -4.757  -0.025  -24.052 1.000 19.851 0 210  THR A CB   1 ? 
ATOM   2953 O OG1  . THR A 1 195 ? -5.400  0.993   -24.832 1.000 23.845 0 210  THR A OG1  1 ? 
ATOM   2954 C CG2  . THR A 1 195 ? -5.501  -1.338  -24.179 1.000 23.275 0 210  THR A CG2  1 ? 
ATOM   2955 H H    . THR A 1 195 ? -6.853  0.233   -22.538 1.000 19.154 0 210  THR A H    1 c 
ATOM   2956 H HA   . THR A 1 195 ? -4.166  -0.110  -22.081 1.000 17.920 0 210  THR A HA   1 c 
ATOM   2957 H HB   . THR A 1 195 ? -3.823  -0.134  -24.351 1.000 20.660 0 210  THR A HB   1 c 
ATOM   2958 H HG1  . THR A 1 195 ? -6.222  1.087   -24.568 0.000 23.840 0 210  THR A HG1  1 c 
ATOM   2959 H HG21 . THR A 1 195 ? -5.316  -1.732  -25.048 1.000 22.178 0 210  THR A HG21 1 c 
ATOM   2960 H HG22 . THR A 1 195 ? -6.455  -1.182  -24.094 1.000 22.144 0 210  THR A HG22 1 c 
ATOM   2961 H HG23 . THR A 1 195 ? -5.208  -1.946  -23.480 1.000 22.137 0 210  THR A HG23 1 c 
ATOM   2962 N N    . VAL A 1 196 ? -3.124  2.111   -22.851 1.000 16.680 0 211  VAL A N    1 ? 
ATOM   2963 C CA   . VAL A 1 196 ? -2.583  3.450   -23.007 1.000 15.755 0 211  VAL A CA   1 ? 
ATOM   2964 C C    . VAL A 1 196 ? -2.593  3.900   -24.472 1.000 16.511 0 211  VAL A C    1 ? 
ATOM   2965 O O    . VAL A 1 196 ? -2.001  4.910   -24.813 1.000 17.539 0 211  VAL A O    1 ? 
ATOM   2966 C CB   . VAL A 1 196 ? -1.168  3.557   -22.401 1.000 15.277 0 211  VAL A CB   1 ? 
ATOM   2967 C CG1  . VAL A 1 196 ? -1.131  3.217   -20.913 1.000 16.335 0 211  VAL A CG1  1 ? 
ATOM   2968 C CG2  . VAL A 1 196 ? -0.142  2.797   -23.211 1.000 17.065 0 211  VAL A CG2  1 ? 
ATOM   2969 H H    . VAL A 1 196 ? -2.572  1.397   -22.993 1.000 16.304 0 211  VAL A H    1 c 
ATOM   2970 H HA   . VAL A 1 196 ? -3.160  4.062   -22.509 1.000 15.989 0 211  VAL A HA   1 c 
ATOM   2971 H HB   . VAL A 1 196 ? -0.914  4.507   -22.466 1.000 15.894 0 211  VAL A HB   1 c 
ATOM   2972 H HG11 . VAL A 1 196 ? -1.347  2.278   -20.788 1.000 16.016 0 211  VAL A HG11 1 c 
ATOM   2973 H HG12 . VAL A 1 196 ? -1.779  3.764   -20.438 1.000 16.014 0 211  VAL A HG12 1 c 
ATOM   2974 H HG13 . VAL A 1 196 ? -0.242  3.393   -20.562 1.000 16.003 0 211  VAL A HG13 1 c 
ATOM   2975 H HG21 . VAL A 1 196 ? 0.701   2.778   -22.728 1.000 16.516 0 211  VAL A HG21 1 c 
ATOM   2976 H HG22 . VAL A 1 196 ? -0.012  3.236   -24.068 1.000 16.521 0 211  VAL A HG22 1 c 
ATOM   2977 H HG23 . VAL A 1 196 ? -0.450  1.888   -23.357 1.000 16.523 0 211  VAL A HG23 1 c 
ATOM   2978 N N    . ASN A 1 197 ? -3.203  3.131   -25.396 1.000 17.946 0 212  ASN A N    1 ? 
ATOM   2979 C CA   . ASN A 1 197 ? -3.061  3.448   -26.815 1.000 17.744 0 212  ASN A CA   1 ? 
ATOM   2980 C C    . ASN A 1 197 ? -3.665  4.794   -27.233 1.000 16.600 0 212  ASN A C    1 ? 
ATOM   2981 O O    . ASN A 1 197 ? -3.108  5.424   -28.122 1.000 19.100 0 212  ASN A O    1 ? 
ATOM   2982 C CB   . ASN A 1 197 ? -3.635  2.326   -27.675 1.000 18.437 0 212  ASN A CB   1 ? 
ATOM   2983 C CG   . ASN A 1 197 ? -2.733  1.122   -27.628 1.000 24.208 0 212  ASN A CG   1 ? 
ATOM   2984 O OD1  . ASN A 1 197 ? -1.511  1.257   -27.665 1.000 28.196 0 212  ASN A OD1  1 ? 
ATOM   2985 N ND2  . ASN A 1 197 ? -3.314  -0.063  -27.646 1.000 35.334 0 212  ASN A ND2  1 ? 
ATOM   2986 H H    . ASN A 1 197 ? -3.711  2.415   -25.145 1.000 17.562 0 212  ASN A H    1 c 
ATOM   2987 H HA   . ASN A 1 197 ? -2.098  3.493   -27.009 1.000 17.774 0 212  ASN A HA   1 c 
ATOM   2988 H HB2  . ASN A 1 197 ? -4.524  2.083   -27.346 1.000 19.589 0 212  ASN A HB2  1 c 
ATOM   2989 H HB3  . ASN A 1 197 ? -3.721  2.632   -28.599 1.000 19.475 0 212  ASN A HB3  1 c 
ATOM   2990 H HD21 . ASN A 1 197 ? -4.120  -0.170  -27.291 1.000 31.176 0 212  ASN A HD21 1 c 
ATOM   2991 H HD22 . ASN A 1 197 ? -2.895  -0.753  -28.013 1.000 31.347 0 212  ASN A HD22 1 c 
ATOM   2992 N N    . ALA A 1 198 ? -4.736  5.304   -26.617 1.000 17.638 0 213  ALA A N    1 ? 
ATOM   2993 C CA   . ALA A 1 198 ? -5.249  6.638   -26.929 1.000 19.598 0 213  ALA A CA   1 ? 
ATOM   2994 C C    . ALA A 1 198 ? -4.266  7.744   -26.586 1.000 18.535 0 213  ALA A C    1 ? 
ATOM   2995 O O    . ALA A 1 198 ? -4.039  8.669   -27.370 1.000 20.100 0 213  ALA A O    1 ? 
ATOM   2996 C CB   . ALA A 1 198 ? -6.534  6.920   -26.218 1.000 22.452 0 213  ALA A CB   1 ? 
ATOM   2997 H H    . ALA A 1 198 ? -5.164  4.806   -25.982 1.000 17.829 0 213  ALA A H    1 c 
ATOM   2998 H HA   . ALA A 1 198 ? -5.417  6.675   -27.911 1.000 19.493 0 213  ALA A HA   1 c 
ATOM   2999 H HB1  . ALA A 1 198 ? -7.195  6.250   -26.460 1.000 21.547 0 213  ALA A HB1  1 c 
ATOM   3000 H HB2  . ALA A 1 198 ? -6.388  6.895   -25.257 1.000 21.533 0 213  ALA A HB2  1 c 
ATOM   3001 H HB3  . ALA A 1 198 ? -6.861  7.800   -26.470 1.000 21.533 0 213  ALA A HB3  1 c 
ATOM   3002 N N    . GLY A 1 199 ? -3.574  7.553   -25.440 1.000 19.389 0 214  GLY A N    1 ? 
ATOM   3003 C CA   . GLY A 1 199 ? -2.567  8.551   -25.072 1.000 19.680 0 214  GLY A CA   1 ? 
ATOM   3004 C C    . GLY A 1 199 ? -1.338  8.532   -25.964 1.000 17.193 0 214  GLY A C    1 ? 
ATOM   3005 O O    . GLY A 1 199 ? -0.763  9.577   -26.285 1.000 18.338 0 214  GLY A O    1 ? 
ATOM   3006 H H    . GLY A 1 199 ? -3.727  6.832   -24.900 1.000 19.234 0 214  GLY A H    1 c 
ATOM   3007 H HA2  . GLY A 1 199 ? -2.979  9.445   -25.105 1.000 19.090 0 214  GLY A HA2  1 c 
ATOM   3008 H HA3  . GLY A 1 199 ? -2.291  8.388   -24.141 1.000 19.023 0 214  GLY A HA3  1 c 
ATOM   3009 N N    . VAL A 1 200 ? -0.910  7.340   -26.402 1.000 14.959 0 215  VAL A N    1 ? 
ATOM   3010 C CA   . VAL A 1 200 ? 0.138   7.215   -27.386 1.000 17.243 0 215  VAL A CA   1 ? 
ATOM   3011 C C    . VAL A 1 200 ? -0.293  7.894   -28.691 1.000 17.407 0 215  VAL A C    1 ? 
ATOM   3012 O O    . VAL A 1 200 ? 0.431   8.711   -29.246 1.000 17.630 0 215  VAL A O    1 ? 
ATOM   3013 C CB   . VAL A 1 200 ? 0.547   5.740   -27.590 1.000 17.271 0 215  VAL A CB   1 ? 
ATOM   3014 C CG1  . VAL A 1 200 ? 1.533   5.542   -28.734 1.000 16.930 0 215  VAL A CG1  1 ? 
ATOM   3015 C CG2  . VAL A 1 200 ? 1.128   5.149   -26.305 1.000 16.683 0 215  VAL A CG2  1 ? 
ATOM   3016 H H    . VAL A 1 200 ? -1.294  6.580   -26.071 1.000 16.031 0 215  VAL A H    1 c 
ATOM   3017 H HA   . VAL A 1 200 ? 0.919   7.693   -27.046 1.000 16.813 0 215  VAL A HA   1 c 
ATOM   3018 H HB   . VAL A 1 200 ? -0.274  5.238   -27.808 1.000 17.091 0 215  VAL A HB   1 c 
ATOM   3019 H HG11 . VAL A 1 200 ? 2.273   6.165   -28.636 1.000 17.030 0 215  VAL A HG11 1 c 
ATOM   3020 H HG12 . VAL A 1 200 ? 1.086   5.703   -29.582 1.000 17.031 0 215  VAL A HG12 1 c 
ATOM   3021 H HG13 . VAL A 1 200 ? 1.872   4.631   -28.717 1.000 17.027 0 215  VAL A HG13 1 c 
ATOM   3022 H HG21 . VAL A 1 200 ? 1.384   4.224   -26.460 1.000 16.851 0 215  VAL A HG21 1 c 
ATOM   3023 H HG22 . VAL A 1 200 ? 0.464   5.185   -25.598 1.000 16.841 0 215  VAL A HG22 1 c 
ATOM   3024 H HG23 . VAL A 1 200 ? 1.911   5.660   -26.038 1.000 16.851 0 215  VAL A HG23 1 c 
ATOM   3025 N N    . ALA A 1 201 ? -1.491  7.547   -29.189 1.000 18.734 0 216  ALA A N    1 ? 
ATOM   3026 C CA   . ALA A 1 201 ? -1.974  8.114   -30.448 1.000 17.579 0 216  ALA A CA   1 ? 
ATOM   3027 C C    . ALA A 1 201 ? -2.113  9.639   -30.424 1.000 19.443 0 216  ALA A C    1 ? 
ATOM   3028 O O    . ALA A 1 201 ? -1.999  10.249  -31.495 1.000 23.034 0 216  ALA A O    1 ? 
ATOM   3029 C CB   . ALA A 1 201 ? -3.327  7.514   -30.725 1.000 18.526 0 216  ALA A CB   1 ? 
ATOM   3030 H H    . ALA A 1 201 ? -2.013  6.946   -28.740 1.000 18.124 0 216  ALA A H    1 c 
ATOM   3031 H HA   . ALA A 1 201 ? -1.341  7.862   -31.176 1.000 18.301 0 216  ALA A HA   1 c 
ATOM   3032 H HB1  . ALA A 1 201 ? -3.236  6.560   -30.886 1.000 18.241 0 216  ALA A HB1  1 c 
ATOM   3033 H HB2  . ALA A 1 201 ? -3.911  7.656   -29.961 1.000 18.240 0 216  ALA A HB2  1 c 
ATOM   3034 H HB3  . ALA A 1 201 ? -3.718  7.936   -31.508 1.000 18.246 0 216  ALA A HB3  1 c 
ATOM   3035 N N    . GLU A 1 202 ? -2.355  10.237  -29.261 1.000 19.977 0 217  GLU A N    1 ? 
ATOM   3036 C CA   . GLU A 1 202 ? -2.484  11.688  -29.209 1.000 21.089 0 217  GLU A CA   1 ? 
ATOM   3037 C C    . GLU A 1 202 ? -1.142  12.412  -29.158 1.000 19.995 0 217  GLU A C    1 ? 
ATOM   3038 O O    . GLU A 1 202 ? -1.119  13.646  -29.184 1.000 19.172 0 217  GLU A O    1 ? 
ATOM   3039 C CB   . GLU A 1 202 ? -3.443  12.142  -28.133 1.000 26.237 0 217  GLU A CB   1 ? 
ATOM   3040 C CG   . GLU A 1 202 ? -2.960  12.016  -26.714 1.000 29.124 0 217  GLU A CG   1 ? 
ATOM   3041 C CD   . GLU A 1 202 ? -4.099  12.507  -25.794 1.000 35.116 0 217  GLU A CD   1 ? 
ATOM   3042 O OE1  . GLU A 1 202 ? -5.049  13.065  -26.305 1.000 42.713 0 217  GLU A OE1  1 ? 
ATOM   3043 O OE2  . GLU A 1 202 ? -4.034  12.320  -24.597 1.000 43.895 0 217  GLU A OE2  1 ? 
ATOM   3044 H H    . GLU A 1 202 ? -2.452  9.748   -28.495 1.000 20.048 0 217  GLU A H    1 c 
ATOM   3045 H HA   . GLU A 1 202 ? -2.916  11.966  -30.056 1.000 21.550 0 217  GLU A HA   1 c 
ATOM   3046 H HB2  . GLU A 1 202 ? -3.665  13.082  -28.300 1.000 25.708 0 217  GLU A HB2  1 c 
ATOM   3047 H HB3  . GLU A 1 202 ? -4.271  11.623  -28.222 1.000 25.705 0 217  GLU A HB3  1 c 
ATOM   3048 H HG2  . GLU A 1 202 ? -2.751  11.082  -26.511 1.000 29.428 0 217  GLU A HG2  1 c 
ATOM   3049 H HG3  . GLU A 1 202 ? -2.163  12.571  -26.576 1.000 29.456 0 217  GLU A HG3  1 c 
ATOM   3050 N N    . ARG A 1 203 ? -0.038  11.675  -29.043 1.000 18.551 0 218  ARG A N    1 ? 
ATOM   3051 C CA   . ARG A 1 203 ? 1.288   12.261  -29.035 1.000 17.218 0 218  ARG A CA   1 ? 
ATOM   3052 C C    . ARG A 1 203 ? 1.470   13.206  -27.848 1.000 16.237 0 218  ARG A C    1 ? 
ATOM   3053 O O    . ARG A 1 203 ? 2.231   14.170  -27.962 1.000 18.931 0 218  ARG A O    1 ? 
ATOM   3054 C CB   . ARG A 1 203 ? 1.580   12.917  -30.403 1.000 19.081 0 218  ARG A CB   1 ? 
ATOM   3055 C CG   . ARG A 1 203 ? 1.609   11.951  -31.581 1.000 26.505 0 218  ARG A CG   1 ? 
ATOM   3056 C CD   . ARG A 1 203 ? 1.697   12.770  -32.889 1.000 36.661 0 218  ARG A CD   1 ? 
ATOM   3057 N NE   . ARG A 1 203 ? 2.979   13.483  -33.010 1.000 40.813 0 218  ARG A NE   1 ? 
ATOM   3058 C CZ   . ARG A 1 203 ? 4.013   13.218  -33.825 1.000 55.394 0 218  ARG A CZ   1 ? 
ATOM   3059 N NH1  . ARG A 1 203 ? 4.048   12.137  -34.595 1.000 53.910 0 218  ARG A NH1  1 ? 
ATOM   3060 N NH2  . ARG A 1 203 ? 5.040   14.057  -33.845 1.000 54.274 0 218  ARG A NH2  1 ? 
ATOM   3061 H H    . ARG A 1 203 ? -0.112  10.769  -28.955 1.000 18.593 0 218  ARG A H    1 c 
ATOM   3062 H HA   . ARG A 1 203 ? 1.938   11.521  -28.927 1.000 17.612 0 218  ARG A HA   1 c 
ATOM   3063 H HB2  . ARG A 1 203 ? 0.903   13.604  -30.577 1.000 20.292 0 218  ARG A HB2  1 c 
ATOM   3064 H HB3  . ARG A 1 203 ? 2.449   13.367  -30.352 1.000 20.321 0 218  ARG A HB3  1 c 
ATOM   3065 H HG2  . ARG A 1 203 ? 2.390   11.361  -31.510 1.000 26.440 0 218  ARG A HG2  1 c 
ATOM   3066 H HG3  . ARG A 1 203 ? 0.792   11.407  -31.588 1.000 26.402 0 218  ARG A HG3  1 c 
ATOM   3067 H HD2  . ARG A 1 203 ? 1.587   12.168  -33.653 1.000 35.132 0 218  ARG A HD2  1 c 
ATOM   3068 H HD3  . ARG A 1 203 ? 0.965   13.420  -32.911 1.000 34.873 0 218  ARG A HD3  1 c 
ATOM   3069 H HE   . ARG A 1 203 ? 3.087   14.171  -32.487 1.000 42.426 0 218  ARG A HE   1 c 
ATOM   3070 H HH11 . ARG A 1 203 ? 4.437   12.179  -35.389 1.000 54.284 0 218  ARG A HH11 1 c 
ATOM   3071 H HH12 . ARG A 1 203 ? 3.687   11.380  -34.311 1.000 54.029 0 218  ARG A HH12 1 c 
ATOM   3072 H HH21 . ARG A 1 203 ? 5.818   13.803  -33.510 1.000 54.616 0 218  ARG A HH21 1 c 
ATOM   3073 H HH22 . ARG A 1 203 ? 4.934   14.871  -34.174 1.000 54.616 0 218  ARG A HH22 1 c 
ATOM   3074 N N    . SER A 1 204 ? 0.870   12.879  -26.698 1.000 16.597 0 219  SER A N    1 ? 
ATOM   3075 C CA   . SER A 1 204 ? 1.101   13.578  -25.448 1.000 15.549 0 219  SER A CA   1 ? 
ATOM   3076 C C    . SER A 1 204 ? 2.468   13.242  -24.872 1.000 14.876 0 219  SER A C    1 ? 
ATOM   3077 O O    . SER A 1 204 ? 2.987   12.155  -25.065 1.000 16.088 0 219  SER A O    1 ? 
ATOM   3078 C CB   . SER A 1 204 ? 0.050   13.245  -24.449 1.000 18.086 0 219  SER A CB   1 ? 
ATOM   3079 O OG   . SER A 1 204 ? 0.097   11.856  -24.119 1.000 19.693 0 219  SER A OG   1 ? 
ATOM   3080 H H    . SER A 1 204 ? 0.289   12.173  -26.694 1.000 16.319 0 219  SER A H    1 c 
ATOM   3081 H HA   . SER A 1 204 ? 1.067   14.552  -25.627 1.000 16.106 0 219  SER A HA   1 c 
ATOM   3082 H HB2  . SER A 1 204 ? 0.189   13.777  -23.642 1.000 17.819 0 219  SER A HB2  1 c 
ATOM   3083 H HB3  . SER A 1 204 ? -0.828  13.464  -24.815 1.000 17.881 0 219  SER A HB3  1 c 
ATOM   3084 H HG   . SER A 1 204 ? -0.506  11.693  -23.550 0.000 19.700 0 219  SER A HG   1 c 
ATOM   3085 N N    . TRP A 1 205 ? 3.024   14.154  -24.099 1.000 14.561 0 220  TRP A N    1 ? 
ATOM   3086 C CA   . TRP A 1 205 ? 4.241   13.832  -23.376 1.000 14.195 0 220  TRP A CA   1 ? 
ATOM   3087 C C    . TRP A 1 205 ? 4.021   12.722  -22.366 1.000 13.305 0 220  TRP A C    1 ? 
ATOM   3088 O O    . TRP A 1 205 ? 4.918   11.922  -22.102 1.000 14.414 0 220  TRP A O    1 ? 
ATOM   3089 C CB   . TRP A 1 205 ? 4.800   15.083  -22.672 1.000 14.664 0 220  TRP A CB   1 ? 
ATOM   3090 C CG   . TRP A 1 205 ? 5.917   14.838  -21.712 1.000 14.866 0 220  TRP A CG   1 ? 
ATOM   3091 C CD1  . TRP A 1 205 ? 7.237   14.546  -21.969 1.000 17.368 0 220  TRP A CD1  1 ? 
ATOM   3092 C CD2  . TRP A 1 205 ? 5.786   14.936  -20.306 1.000 14.212 0 220  TRP A CD2  1 ? 
ATOM   3093 N NE1  . TRP A 1 205 ? 7.922   14.446  -20.790 1.000 15.886 0 220  TRP A NE1  1 ? 
ATOM   3094 C CE2  . TRP A 1 205 ? 7.059   14.689  -19.757 1.000 15.460 0 220  TRP A CE2  1 ? 
ATOM   3095 C CE3  . TRP A 1 205 ? 4.710   15.187  -19.435 1.000 14.848 0 220  TRP A CE3  1 ? 
ATOM   3096 C CZ2  . TRP A 1 205 ? 7.277   14.719  -18.390 1.000 15.107 0 220  TRP A CZ2  1 ? 
ATOM   3097 C CZ3  . TRP A 1 205 ? 4.943   15.221  -18.074 1.000 14.975 0 220  TRP A CZ3  1 ? 
ATOM   3098 C CH2  . TRP A 1 205 ? 6.222   14.994  -17.564 1.000 15.250 0 220  TRP A CH2  1 ? 
ATOM   3099 H H    . TRP A 1 205 ? 2.656   14.987  -24.021 1.000 14.598 0 220  TRP A H    1 c 
ATOM   3100 H HA   . TRP A 1 205 ? 4.918   13.524  -24.033 1.000 14.208 0 220  TRP A HA   1 c 
ATOM   3101 H HB2  . TRP A 1 205 ? 5.110   15.710  -23.360 1.000 14.608 0 220  TRP A HB2  1 c 
ATOM   3102 H HB3  . TRP A 1 205 ? 4.065   15.522  -22.193 1.000 14.623 0 220  TRP A HB3  1 c 
ATOM   3103 H HD1  . TRP A 1 205 ? 7.623   14.436  -22.823 1.000 16.397 0 220  TRP A HD1  1 c 
ATOM   3104 H HE1  . TRP A 1 205 ? 8.775   14.274  -20.711 1.000 16.095 0 220  TRP A HE1  1 c 
ATOM   3105 H HE3  . TRP A 1 205 ? 3.851   15.362  -19.778 1.000 14.743 0 220  TRP A HE3  1 c 
ATOM   3106 H HZ2  . TRP A 1 205 ? 8.136   14.558  -18.037 1.000 15.216 0 220  TRP A HZ2  1 c 
ATOM   3107 H HZ3  . TRP A 1 205 ? 4.232   15.405  -17.483 1.000 15.007 0 220  TRP A HZ3  1 c 
ATOM   3108 H HH2  . TRP A 1 205 ? 6.358   15.007  -16.634 1.000 15.158 0 220  TRP A HH2  1 c 
ATOM   3109 N N    . LEU A 1 206 ? 2.835   12.653  -21.757 1.000 14.029 0 221  LEU A N    1 ? 
ATOM   3110 C CA   . LEU A 1 206 ? 2.602   11.699  -20.677 1.000 14.188 0 221  LEU A CA   1 ? 
ATOM   3111 C C    . LEU A 1 206 ? 2.873   10.264  -21.137 1.000 15.129 0 221  LEU A C    1 ? 
ATOM   3112 O O    . LEU A 1 206 ? 3.287   9.438   -20.323 1.000 14.989 0 221  LEU A O    1 ? 
ATOM   3113 C CB   . LEU A 1 206 ? 1.169   11.766  -20.172 1.000 16.485 0 221  LEU A CB   1 ? 
ATOM   3114 C CG   . LEU A 1 206 ? 0.926   11.107  -18.808 1.000 18.039 0 221  LEU A CG   1 ? 
ATOM   3115 C CD1  . LEU A 1 206 ? 1.849   11.693  -17.772 1.000 19.748 0 221  LEU A CD1  1 ? 
ATOM   3116 C CD2  . LEU A 1 206 ? -0.497  11.227  -18.341 1.000 21.853 0 221  LEU A CD2  1 ? 
ATOM   3117 H H    . LEU A 1 206 ? 2.157   13.212  -22.009 1.000 13.932 0 221  LEU A H    1 c 
ATOM   3118 H HA   . LEU A 1 206 ? 3.222   11.915  -19.937 1.000 14.773 0 221  LEU A HA   1 c 
ATOM   3119 H HB2  . LEU A 1 206 ? 0.908   12.713  -20.110 1.000 16.252 0 221  LEU A HB2  1 c 
ATOM   3120 H HB3  . LEU A 1 206 ? 0.586   11.333  -20.837 1.000 16.248 0 221  LEU A HB3  1 c 
ATOM   3121 H HG   . LEU A 1 206 ? 1.136   10.141  -18.890 1.000 18.677 0 221  LEU A HG   1 c 
ATOM   3122 H HD11 . LEU A 1 206 ? 2.730   11.293  -17.858 1.000 19.150 0 221  LEU A HD11 1 c 
ATOM   3123 H HD12 . LEU A 1 206 ? 1.499   11.511  -16.884 1.000 19.199 0 221  LEU A HD12 1 c 
ATOM   3124 H HD13 . LEU A 1 206 ? 1.915   12.654  -17.902 1.000 19.188 0 221  LEU A HD13 1 c 
ATOM   3125 H HD21 . LEU A 1 206 ? -1.091  10.838  -19.005 1.000 20.642 0 221  LEU A HD21 1 c 
ATOM   3126 H HD22 . LEU A 1 206 ? -0.721  12.165  -18.219 1.000 20.670 0 221  LEU A HD22 1 c 
ATOM   3127 H HD23 . LEU A 1 206 ? -0.604  10.757  -17.497 1.000 20.634 0 221  LEU A HD23 1 c 
ATOM   3128 N N    . TYR A 1 207 ? 2.589   9.930   -22.415 1.000 16.132 0 222  TYR A N    1 ? 
ATOM   3129 C CA   . TYR A 1 207 ? 2.818   8.578   -22.890 1.000 15.795 0 222  TYR A CA   1 ? 
ATOM   3130 C C    . TYR A 1 207 ? 3.988   8.449   -23.872 1.000 14.999 0 222  TYR A C    1 ? 
ATOM   3131 O O    . TYR A 1 207 ? 4.236   7.380   -24.414 1.000 15.482 0 222  TYR A O    1 ? 
ATOM   3132 C CB   . TYR A 1 207 ? 1.504   8.017   -23.446 1.000 16.316 0 222  TYR A CB   1 ? 
ATOM   3133 C CG   . TYR A 1 207 ? 0.434   7.859   -22.390 1.000 14.963 0 222  TYR A CG   1 ? 
ATOM   3134 C CD1  . TYR A 1 207 ? 0.447   6.748   -21.533 1.000 14.904 0 222  TYR A CD1  1 ? 
ATOM   3135 C CD2  . TYR A 1 207 ? -0.510  8.848   -22.162 1.000 16.559 0 222  TYR A CD2  1 ? 
ATOM   3136 C CE1  . TYR A 1 207 ? -0.491  6.620   -20.524 1.000 15.141 0 222  TYR A CE1  1 ? 
ATOM   3137 C CE2  . TYR A 1 207 ? -1.468  8.711   -21.173 1.000 17.238 0 222  TYR A CE2  1 ? 
ATOM   3138 C CZ   . TYR A 1 207 ? -1.467  7.587   -20.352 1.000 15.774 0 222  TYR A CZ   1 ? 
ATOM   3139 O OH   . TYR A 1 207 ? -2.412  7.520   -19.349 1.000 18.236 0 222  TYR A OH   1 ? 
ATOM   3140 H H    . TYR A 1 207 ? 2.238   10.551  -22.987 1.000 15.768 0 222  TYR A H    1 c 
ATOM   3141 H HA   . TYR A 1 207 ? 3.050   8.026   -22.097 1.000 15.790 0 222  TYR A HA   1 c 
ATOM   3142 H HB2  . TYR A 1 207 ? 1.176   8.621   -24.148 1.000 15.878 0 222  TYR A HB2  1 c 
ATOM   3143 H HB3  . TYR A 1 207 ? 1.683   7.140   -23.854 1.000 15.876 0 222  TYR A HB3  1 c 
ATOM   3144 H HD1  . TYR A 1 207 ? 1.100   6.077   -21.649 1.000 15.011 0 222  TYR A HD1  1 c 
ATOM   3145 H HD2  . TYR A 1 207 ? -0.531  9.606   -22.724 1.000 16.315 0 222  TYR A HD2  1 c 
ATOM   3146 H HE1  . TYR A 1 207 ? -0.486  5.857   -19.972 1.000 15.269 0 222  TYR A HE1  1 c 
ATOM   3147 H HE2  . TYR A 1 207 ? -2.115  9.384   -21.047 1.000 16.709 0 222  TYR A HE2  1 c 
ATOM   3148 H HH   . TYR A 1 207 ? -2.121  7.910   -18.643 0.000 18.250 0 222  TYR A HH   1 c 
ATOM   3149 N N    . LEU A 1 208 ? 4.776   9.536   -24.047 1.000 13.243 0 223  LEU A N    1 ? 
ATOM   3150 C CA   . LEU A 1 208 ? 6.062   9.550   -24.711 1.000 14.017 0 223  LEU A CA   1 ? 
ATOM   3151 C C    . LEU A 1 208 ? 5.984   9.010   -26.153 1.000 13.284 0 223  LEU A C    1 ? 
ATOM   3152 O O    . LEU A 1 208 ? 6.965   8.508   -26.664 1.000 14.124 0 223  LEU A O    1 ? 
ATOM   3153 C CB   . LEU A 1 208 ? 7.109   8.812   -23.848 1.000 14.243 0 223  LEU A CB   1 ? 
ATOM   3154 C CG   . LEU A 1 208 ? 7.422   9.463   -22.491 1.000 15.368 0 223  LEU A CG   1 ? 
ATOM   3155 C CD1  . LEU A 1 208 ? 8.296   8.541   -21.688 1.000 14.652 0 223  LEU A CD1  1 ? 
ATOM   3156 C CD2  . LEU A 1 208 ? 8.062   10.834  -22.631 1.000 15.588 0 223  LEU A CD2  1 ? 
ATOM   3157 H H    . LEU A 1 208 ? 4.467   10.333  -23.724 1.000 13.859 0 223  LEU A H    1 c 
ATOM   3158 H HA   . LEU A 1 208 ? 6.337   10.497  -24.778 1.000 13.812 0 223  LEU A HA   1 c 
ATOM   3159 H HB2  . LEU A 1 208 ? 6.788   7.895   -23.688 1.000 14.450 0 223  LEU A HB2  1 c 
ATOM   3160 H HB3  . LEU A 1 208 ? 7.947   8.753   -24.362 1.000 14.440 0 223  LEU A HB3  1 c 
ATOM   3161 H HG   . LEU A 1 208 ? 6.567   9.576   -22.000 1.000 15.050 0 223  LEU A HG   1 c 
ATOM   3162 H HD11 . LEU A 1 208 ? 7.836   7.697   -21.549 1.000 14.854 0 223  LEU A HD11 1 c 
ATOM   3163 H HD12 . LEU A 1 208 ? 8.494   8.947   -20.828 1.000 14.860 0 223  LEU A HD12 1 c 
ATOM   3164 H HD13 . LEU A 1 208 ? 9.127   8.381   -22.168 1.000 14.860 0 223  LEU A HD13 1 c 
ATOM   3165 H HD21 . LEU A 1 208 ? 7.422   11.456  -23.015 1.000 15.496 0 223  LEU A HD21 1 c 
ATOM   3166 H HD22 . LEU A 1 208 ? 8.840   10.772  -23.212 1.000 15.516 0 223  LEU A HD22 1 c 
ATOM   3167 H HD23 . LEU A 1 208 ? 8.338   11.155  -21.756 1.000 15.516 0 223  LEU A HD23 1 c 
ATOM   3168 N N    . LYS A 1 209 ? 4.854   9.186   -26.845 1.000 14.685 0 224  LYS A N    1 ? 
ATOM   3169 C CA   . LYS A 1 209 ? 4.715   8.657   -28.203 1.000 15.333 0 224  LYS A CA   1 ? 
ATOM   3170 C C    . LYS A 1 209 ? 5.023   7.154   -28.269 1.000 17.208 0 224  LYS A C    1 ? 
ATOM   3171 O O    . LYS A 1 209 ? 5.367   6.609   -29.335 1.000 17.099 0 224  LYS A O    1 ? 
ATOM   3172 C CB   . LYS A 1 209 ? 5.548   9.486   -29.203 1.000 16.840 0 224  LYS A CB   1 ? 
ATOM   3173 C CG   . LYS A 1 209 ? 5.003   10.883  -29.369 1.000 18.107 0 224  LYS A CG   1 ? 
ATOM   3174 C CD   . LYS A 1 209 ? 5.813   11.686  -30.366 1.000 18.511 0 224  LYS A CD   1 ? 
ATOM   3175 C CE   . LYS A 1 209 ? 7.071   12.121  -29.823 1.000 21.671 0 224  LYS A CE   1 ? 
ATOM   3176 N NZ   . LYS A 1 209 ? 7.914   12.801  -30.836 1.000 22.673 0 224  LYS A NZ   1 ? 
ATOM   3177 H H    . LYS A 1 209 ? 4.159   9.650   -26.476 1.000 14.467 0 224  LYS A H    1 c 
ATOM   3178 H HA   . LYS A 1 209 ? 3.767   8.773   -28.466 1.000 15.801 0 224  LYS A HA   1 c 
ATOM   3179 H HB2  . LYS A 1 209 ? 6.475   9.539   -28.892 1.000 16.788 0 224  LYS A HB2  1 c 
ATOM   3180 H HB3  . LYS A 1 209 ? 5.544   9.041   -30.077 1.000 16.789 0 224  LYS A HB3  1 c 
ATOM   3181 H HG2  . LYS A 1 209 ? 4.072   10.828  -29.676 1.000 17.893 0 224  LYS A HG2  1 c 
ATOM   3182 H HG3  . LYS A 1 209 ? 5.015   11.336  -28.498 1.000 17.887 0 224  LYS A HG3  1 c 
ATOM   3183 H HD2  . LYS A 1 209 ? 5.981   11.135  -31.162 1.000 19.100 0 224  LYS A HD2  1 c 
ATOM   3184 H HD3  . LYS A 1 209 ? 5.294   12.472  -30.643 1.000 19.139 0 224  LYS A HD3  1 c 
ATOM   3185 H HE2  . LYS A 1 209 ? 6.906   12.738  -29.089 1.000 21.041 0 224  LYS A HE2  1 c 
ATOM   3186 H HE3  . LYS A 1 209 ? 7.560   11.357  -29.470 1.000 21.111 0 224  LYS A HE3  1 c 
ATOM   3187 H HZ1  . LYS A 1 209 ? 7.406   13.367  -31.328 1.000 22.331 0 224  LYS A HZ1  1 c 
ATOM   3188 H HZ2  . LYS A 1 209 ? 8.289   12.187  -31.385 1.000 22.401 0 224  LYS A HZ2  1 c 
ATOM   3189 H HZ3  . LYS A 1 209 ? 8.567   13.275  -30.424 1.000 22.401 0 224  LYS A HZ3  1 c 
ATOM   3190 N N    . GLY A 1 210 ? 4.843   6.457   -27.129 1.000 15.184 0 225  GLY A N    1 ? 
ATOM   3191 C CA   . GLY A 1 210 ? 5.108   5.031   -27.055 1.000 16.336 0 225  GLY A CA   1 ? 
ATOM   3192 C C    . GLY A 1 210 ? 6.553   4.665   -26.691 1.000 15.931 0 225  GLY A C    1 ? 
ATOM   3193 O O    . GLY A 1 210 ? 6.840   3.475   -26.459 1.000 17.577 0 225  GLY A O    1 ? 
ATOM   3194 H H    . GLY A 1 210 ? 4.521   6.880   -26.386 1.000 15.872 0 225  GLY A H    1 c 
ATOM   3195 H HA2  . GLY A 1 210 ? 4.503   4.638   -26.384 1.000 15.980 0 225  GLY A HA2  1 c 
ATOM   3196 H HA3  . GLY A 1 210 ? 4.885   4.624   -27.923 1.000 15.979 0 225  GLY A HA3  1 c 
ATOM   3197 N N    . SER A 1 211 ? 7.445   5.660   -26.569 1.000 16.162 0 226  SER A N    1 ? 
ATOM   3198 C CA   . SER A 1 211 ? 8.858   5.444   -26.216 1.000 16.225 0 226  SER A CA   1 ? 
ATOM   3199 C C    . SER A 1 211 ? 9.048   5.536   -24.696 1.000 16.189 0 226  SER A C    1 ? 
ATOM   3200 O O    . SER A 1 211 ? 9.935   6.190   -24.196 1.000 16.357 0 226  SER A O    1 ? 
ATOM   3201 C CB   . SER A 1 211 ? 9.754   6.422   -26.934 1.000 19.288 0 226  SER A CB   1 ? 
ATOM   3202 O OG   . SER A 1 211 ? 9.646   6.212   -28.335 1.000 19.452 0 226  SER A OG   1 ? 
ATOM   3203 H H    . SER A 1 211 ? 7.166   6.518   -26.709 1.000 16.122 0 226  SER A H    1 c 
ATOM   3204 H HA   . SER A 1 211 ? 9.110   4.529   -26.501 1.000 16.739 0 226  SER A HA   1 c 
ATOM   3205 H HB2  . SER A 1 211 ? 9.486   7.335   -26.715 1.000 18.583 0 226  SER A HB2  1 c 
ATOM   3206 H HB3  . SER A 1 211 ? 10.679  6.290   -26.652 1.000 18.573 0 226  SER A HB3  1 c 
ATOM   3207 H HG   . SER A 1 211 ? 10.153  6.765   -28.728 0.000 19.530 0 226  SER A HG   1 c 
ATOM   3208 N N    . TYR A 1 212 ? 8.154   4.869   -23.981 1.000 15.719 0 227  TYR A N    1 ? 
ATOM   3209 C CA   . TYR A 1 212 ? 8.183   4.743   -22.520 1.000 15.408 0 227  TYR A CA   1 ? 
ATOM   3210 C C    . TYR A 1 212 ? 9.006   3.524   -22.134 1.000 16.011 0 227  TYR A C    1 ? 
ATOM   3211 O O    . TYR A 1 212 ? 9.409   2.698   -22.967 1.000 16.743 0 227  TYR A O    1 ? 
ATOM   3212 C CB   . TYR A 1 212 ? 6.775   4.658   -21.938 1.000 15.060 0 227  TYR A CB   1 ? 
ATOM   3213 C CG   . TYR A 1 212 ? 5.859   3.612   -22.530 1.000 15.856 0 227  TYR A CG   1 ? 
ATOM   3214 C CD1  . TYR A 1 212 ? 5.926   2.293   -22.100 1.000 17.177 0 227  TYR A CD1  1 ? 
ATOM   3215 C CD2  . TYR A 1 212 ? 4.966   3.945   -23.525 1.000 16.017 0 227  TYR A CD2  1 ? 
ATOM   3216 C CE1  . TYR A 1 212 ? 5.097   1.330   -22.658 1.000 18.104 0 227  TYR A CE1  1 ? 
ATOM   3217 C CE2  . TYR A 1 212 ? 4.150   2.990   -24.093 1.000 17.356 0 227  TYR A CE2  1 ? 
ATOM   3218 C CZ   . TYR A 1 212 ? 4.211   1.690   -23.646 1.000 18.854 0 227  TYR A CZ   1 ? 
ATOM   3219 O OH   . TYR A 1 212 ? 3.398   0.780   -24.247 1.000 21.027 0 227  TYR A OH   1 ? 
ATOM   3220 H H    . TYR A 1 212 ? 7.484   4.440   -24.428 1.000 15.763 0 227  TYR A H    1 c 
ATOM   3221 H HA   . TYR A 1 212 ? 8.626   5.550   -22.145 1.000 15.516 0 227  TYR A HA   1 c 
ATOM   3222 H HB2  . TYR A 1 212 ? 6.852   4.491   -20.973 1.000 15.322 0 227  TYR A HB2  1 c 
ATOM   3223 H HB3  . TYR A 1 212 ? 6.349   5.538   -22.042 1.000 15.329 0 227  TYR A HB3  1 c 
ATOM   3224 H HD1  . TYR A 1 212 ? 6.534   2.050   -21.420 1.000 17.073 0 227  TYR A HD1  1 c 
ATOM   3225 H HD2  . TYR A 1 212 ? 4.923   4.836   -23.833 1.000 16.303 0 227  TYR A HD2  1 c 
ATOM   3226 H HE1  . TYR A 1 212 ? 5.143   0.436   -22.366 1.000 18.035 0 227  TYR A HE1  1 c 
ATOM   3227 H HE2  . TYR A 1 212 ? 3.541   3.229   -24.771 1.000 17.362 0 227  TYR A HE2  1 c 
ATOM   3228 H HH   . TYR A 1 212 ? 2.656   0.720   -23.820 0.000 21.060 0 227  TYR A HH   1 c 
ATOM   3229 N N    . MET A 1 213 ? 9.352   3.482   -20.850 1.000 15.567 0 228  MET A N    1 ? 
ATOM   3230 C CA   . MET A 1 213 ? 10.170  2.398   -20.341 1.000 15.028 0 228  MET A CA   1 ? 
ATOM   3231 C C    . MET A 1 213 ? 9.312   1.158   -20.100 1.000 15.540 0 228  MET A C    1 ? 
ATOM   3232 O O    . MET A 1 213 ? 8.272   1.255   -19.472 1.000 15.903 0 228  MET A O    1 ? 
ATOM   3233 C CB   . MET A 1 213 ? 10.833  2.804   -19.022 1.000 17.336 0 228  MET A CB   1 ? 
ATOM   3234 C CG   . MET A 1 213 ? 11.779  3.958   -19.157 1.000 16.650 0 228  MET A CG   1 ? 
ATOM   3235 S SD   . MET A 1 213 ? 12.396  4.533   -17.542 1.000 21.084 0 228  MET A SD   1 ? 
ATOM   3236 C CE   . MET A 1 213 ? 13.062  2.958   -16.946 1.000 26.528 0 228  MET A CE   1 ? 
ATOM   3237 H H    . MET A 1 213 ? 9.075   4.140   -20.279 1.000 15.554 0 228  MET A H    1 c 
ATOM   3238 H HA   . MET A 1 213 ? 10.868  2.187   -21.011 1.000 15.635 0 228  MET A HA   1 c 
ATOM   3239 H HB2  . MET A 1 213 ? 10.134  3.037   -18.377 1.000 16.631 0 228  MET A HB2  1 c 
ATOM   3240 H HB3  . MET A 1 213 ? 11.320  2.029   -18.671 1.000 16.715 0 228  MET A HB3  1 c 
ATOM   3241 H HG2  . MET A 1 213 ? 12.540  3.692   -19.708 1.000 17.547 0 228  MET A HG2  1 c 
ATOM   3242 H HG3  . MET A 1 213 ? 11.327  4.700   -19.604 1.000 17.559 0 228  MET A HG3  1 c 
ATOM   3243 H HE1  . MET A 1 213 ? 13.540  3.104   -16.110 1.000 24.860 0 228  MET A HE1  1 c 
ATOM   3244 H HE2  . MET A 1 213 ? 12.331  2.333   -16.787 1.000 24.878 0 228  MET A HE2  1 c 
ATOM   3245 H HE3  . MET A 1 213 ? 13.672  2.590   -17.612 1.000 24.982 0 228  MET A HE3  1 c 
ATOM   3246 N N    . ARG A 1 214 ? 9.763   0.007   -20.645 1.000 15.908 0 229  ARG A N    1 ? 
ATOM   3247 C CA   . ARG A 1 214 ? 9.174   -1.301  -20.370 1.000 16.419 0 229  ARG A CA   1 ? 
ATOM   3248 C C    . ARG A 1 214 ? 10.181  -2.077  -19.526 1.000 16.649 0 229  ARG A C    1 ? 
ATOM   3249 O O    . ARG A 1 214 ? 11.205  -2.556  -20.036 1.000 18.841 0 229  ARG A O    1 ? 
ATOM   3250 C CB   . ARG A 1 214 ? 8.886   -2.054  -21.681 1.000 20.240 0 229  ARG A CB   1 ? 
ATOM   3251 C CG   . ARG A 1 214 ? 7.821   -1.385  -22.551 1.000 23.845 0 229  ARG A CG   1 ? 
ATOM   3252 C CD   . ARG A 1 214 ? 8.122   -1.532  -24.053 1.000 31.132 0 229  ARG A CD   1 ? 
ATOM   3253 N NE   . ARG A 1 214 ? 7.073   -0.950  -24.909 1.000 30.076 0 229  ARG A NE   1 ? 
ATOM   3254 C CZ   . ARG A 1 214 ? 7.106   0.266   -25.443 1.000 31.645 0 229  ARG A CZ   1 ? 
ATOM   3255 N NH1  . ARG A 1 214 ? 8.034   1.124   -25.109 1.000 33.110 0 229  ARG A NH1  1 ? 
ATOM   3256 N NH2  . ARG A 1 214 ? 6.177   0.650   -26.302 1.000 27.734 0 229  ARG A NH2  1 ? 
ATOM   3257 H H    . ARG A 1 214 ? 10.473  0.045   -21.219 1.000 15.924 0 229  ARG A H    1 c 
ATOM   3258 H HA   . ARG A 1 214 ? 8.335   -1.179  -19.858 1.000 16.964 0 229  ARG A HA   1 c 
ATOM   3259 H HB2  . ARG A 1 214 ? 9.718   -2.123  -22.196 1.000 20.085 0 229  ARG A HB2  1 c 
ATOM   3260 H HB3  . ARG A 1 214 ? 8.592   -2.965  -21.464 1.000 20.048 0 229  ARG A HB3  1 c 
ATOM   3261 H HG2  . ARG A 1 214 ? 6.946   -1.789  -22.359 1.000 24.384 0 229  ARG A HG2  1 c 
ATOM   3262 H HG3  . ARG A 1 214 ? 7.769   -0.431  -22.327 1.000 24.296 0 229  ARG A HG3  1 c 
ATOM   3263 H HD2  . ARG A 1 214 ? 8.978   -1.099  -24.251 1.000 29.122 0 229  ARG A HD2  1 c 
ATOM   3264 H HD3  . ARG A 1 214 ? 8.215   -2.483  -24.265 1.000 29.092 0 229  ARG A HD3  1 c 
ATOM   3265 H HE   . ARG A 1 214 ? 6.374   -1.442  -25.078 1.000 30.646 0 229  ARG A HE   1 c 
ATOM   3266 H HH11 . ARG A 1 214 ? 8.453   1.583   -25.740 1.000 32.618 0 229  ARG A HH11 1 c 
ATOM   3267 H HH12 . ARG A 1 214 ? 8.237   1.247   -24.256 1.000 32.635 0 229  ARG A HH12 1 c 
ATOM   3268 H HH21 . ARG A 1 214 ? 6.258   1.427   -26.716 1.000 28.948 0 229  ARG A HH21 1 c 
ATOM   3269 H HH22 . ARG A 1 214 ? 5.472   0.137   -26.447 1.000 28.921 0 229  ARG A HH22 1 c 
ATOM   3270 N N    . CYS A 1 215 ? 9.914   -2.136  -18.217 1.000 16.219 0 230  CYS A N    1 ? 
ATOM   3271 C CA   . CYS A 1 215 ? 10.896  -2.679  -17.290 1.000 15.591 0 230  CYS A CA   1 ? 
ATOM   3272 C C    . CYS A 1 215 ? 10.966  -4.195  -17.386 1.000 16.452 0 230  CYS A C    1 ? 
ATOM   3273 O O    . CYS A 1 215 ? 9.951   -4.874  -17.550 1.000 18.712 0 230  CYS A O    1 ? 
ATOM   3274 C CB   . CYS A 1 215 ? 10.531  -2.320  -15.858 1.000 16.335 0 230  CYS A CB   1 ? 
ATOM   3275 S SG   . CYS A 1 215 ? 10.658  -0.553  -15.456 1.000 18.413 0 230  CYS A SG   1 ? 
ATOM   3276 H H    . CYS A 1 215 ? 9.112   -1.838  -17.896 1.000 16.186 0 230  CYS A H    1 c 
ATOM   3277 H HA   . CYS A 1 215 ? 11.782  -2.299  -17.514 1.000 16.059 0 230  CYS A HA   1 c 
ATOM   3278 H HB2  . CYS A 1 215 ? 9.610   -2.613  -15.679 1.000 16.515 0 230  CYS A HB2  1 c 
ATOM   3279 H HB3  . CYS A 1 215 ? 11.124  -2.813  -15.249 1.000 16.527 0 230  CYS A HB3  1 c 
ATOM   3280 H HG   . CYS A 1 215 ? 10.314  -0.629  -14.297 0.000 18.400 0 230  CYS A HG   1 c 
ATOM   3281 N N    . ASP A 1 216 ? 12.170  -4.714  -17.216 1.000 16.983 0 231  ASP A N    1 ? 
ATOM   3282 C CA   . ASP A 1 216 ? 12.358  -6.083  -16.753 1.000 18.830 0 231  ASP A CA   1 ? 
ATOM   3283 C C    . ASP A 1 216 ? 12.451  -6.076  -15.222 1.000 18.287 0 231  ASP A C    1 ? 
ATOM   3284 O O    . ASP A 1 216 ? 12.294  -5.041  -14.557 1.000 17.169 0 231  ASP A O    1 ? 
ATOM   3285 C CB   . ASP A 1 216 ? 13.550  -6.716  -17.466 1.000 20.381 0 231  ASP A CB   1 ? 
ATOM   3286 C CG   . ASP A 1 216 ? 14.918  -6.153  -17.113 1.000 27.340 0 231  ASP A CG   1 ? 
ATOM   3287 O OD1  . ASP A 1 216 ? 15.004  -5.286  -16.257 1.000 22.637 0 231  ASP A OD1  1 ? 
ATOM   3288 O OD2  . ASP A 1 216 ? 15.932  -6.594  -17.690 1.000 32.076 0 231  ASP A OD2  1 ? 
ATOM   3289 H H    . ASP A 1 216 ? 12.907  -4.205  -17.396 1.000 17.291 0 231  ASP A H    1 c 
ATOM   3290 H HA   . ASP A 1 216 ? 11.566  -6.607  -17.009 1.000 18.619 0 231  ASP A HA   1 c 
ATOM   3291 H HB2  . ASP A 1 216 ? 13.558  -7.676  -17.270 1.000 21.439 0 231  ASP A HB2  1 c 
ATOM   3292 H HB3  . ASP A 1 216 ? 13.422  -6.611  -18.432 1.000 21.430 0 231  ASP A HB3  1 c 
ATOM   3293 N N    . ARG A 1 217 ? 12.668  -7.231  -14.608 1.000 18.326 0 232  ARG A N    1 ? 
ATOM   3294 C CA   . ARG A 1 217 ? 12.691  -7.299  -13.157 1.000 18.756 0 232  ARG A CA   1 ? 
ATOM   3295 C C    . ARG A 1 217 ? 13.833  -6.484  -12.566 1.000 18.200 0 232  ARG A C    1 ? 
ATOM   3296 O O    . ARG A 1 217 ? 13.709  -5.909  -11.490 1.000 18.329 0 232  ARG A O    1 ? 
ATOM   3297 C CB   . ARG A 1 217 ? 12.786  -8.760  -12.684 1.000 21.123 0 232  ARG A CB   1 ? 
ATOM   3298 C CG   . ARG A 1 217 ? 11.434  -9.445  -12.781 1.000 24.118 0 232  ARG A CG   1 ? 
ATOM   3299 C CD   . ARG A 1 217 ? 10.496  -9.193  -11.626 1.000 22.585 0 232  ARG A CD   1 ? 
ATOM   3300 N NE   . ARG A 1 217 ? 9.292   -9.980  -11.885 1.000 23.430 0 232  ARG A NE   1 ? 
ATOM   3301 C CZ   . ARG A 1 217 ? 8.154   -9.581  -12.417 1.000 27.020 0 232  ARG A CZ   1 ? 
ATOM   3302 N NH1  . ARG A 1 217 ? 7.928   -8.311  -12.706 1.000 23.663 0 232  ARG A NH1  1 ? 
ATOM   3303 N NH2  . ARG A 1 217 ? 7.192   -10.459 -12.659 1.000 29.430 0 232  ARG A NH2  1 ? 
ATOM   3304 H H    . ARG A 1 217 ? 12.800  -7.993  -15.095 1.000 18.485 0 232  ARG A H    1 c 
ATOM   3305 H HA   . ARG A 1 217 ? 11.840  -6.925  -12.821 1.000 18.983 0 232  ARG A HA   1 c 
ATOM   3306 H HB2  . ARG A 1 217 ? 13.437  -9.244  -13.235 1.000 21.268 0 232  ARG A HB2  1 c 
ATOM   3307 H HB3  . ARG A 1 217 ? 13.095  -8.784  -11.753 1.000 21.197 0 232  ARG A HB3  1 c 
ATOM   3308 H HG2  . ARG A 1 217 ? 10.995  -9.153  -13.606 1.000 22.985 0 232  ARG A HG2  1 c 
ATOM   3309 H HG3  . ARG A 1 217 ? 11.578  -10.413 -12.860 1.000 23.036 0 232  ARG A HG3  1 c 
ATOM   3310 H HD2  . ARG A 1 217 ? 10.905  -9.484  -10.785 1.000 23.109 0 232  ARG A HD2  1 c 
ATOM   3311 H HD3  . ARG A 1 217 ? 10.271  -8.247  -11.555 1.000 23.099 0 232  ARG A HD3  1 c 
ATOM   3312 H HE   . ARG A 1 217 ? 9.328   -10.821 -11.658 1.000 24.095 0 232  ARG A HE   1 c 
ATOM   3313 H HH11 . ARG A 1 217 ? 7.289   -8.102  -13.290 1.000 24.696 0 232  ARG A HH11 1 c 
ATOM   3314 H HH12 . ARG A 1 217 ? 8.404   -7.672  -12.316 1.000 24.581 0 232  ARG A HH12 1 c 
ATOM   3315 H HH21 . ARG A 1 217 ? 6.380   -10.176 -12.872 1.000 28.566 0 232  ARG A HH21 1 c 
ATOM   3316 H HH22 . ARG A 1 217 ? 7.362   -11.327 -12.609 1.000 28.559 0 232  ARG A HH22 1 c 
ATOM   3317 N N    . LYS A 1 218 ? 14.962  -6.454  -13.254 1.000 19.278 0 233  LYS A N    1 ? 
ATOM   3318 C CA   . LYS A 1 218 ? 16.116  -5.716  -12.766 1.000 20.704 0 233  LYS A CA   1 ? 
ATOM   3319 C C    . LYS A 1 218 ? 15.868  -4.201  -12.796 1.000 18.962 0 233  LYS A C    1 ? 
ATOM   3320 O O    . LYS A 1 218 ? 16.264  -3.458  -11.896 1.000 18.856 0 233  LYS A O    1 ? 
ATOM   3321 C CB   . LYS A 1 218 ? 17.384  -6.058  -13.545 1.000 25.717 0 233  LYS A CB   1 ? 
ATOM   3322 C CG   . LYS A 1 218 ? 17.623  -7.518  -13.846 1.000 35.407 0 233  LYS A CG   1 ? 
ATOM   3323 C CD   . LYS A 1 218 ? 17.988  -8.345  -12.630 1.000 38.465 0 233  LYS A CD   1 ? 
ATOM   3324 C CE   . LYS A 1 218 ? 18.699  -9.635  -13.000 1.000 41.991 0 233  LYS A CE   1 ? 
ATOM   3325 N NZ   . LYS A 1 218 ? 17.984  -10.384 -14.029 1.000 47.941 0 233  LYS A NZ   1 ? 
ATOM   3326 H H    . LYS A 1 218 ? 15.017  -6.888  -14.056 1.000 19.523 0 233  LYS A H    1 c 
ATOM   3327 H HA   . LYS A 1 218 ? 16.269  -5.981  -11.823 1.000 20.890 0 233  LYS A HA   1 c 
ATOM   3328 H HB2  . LYS A 1 218 ? 17.362  -5.572  -14.397 1.000 26.330 0 233  LYS A HB2  1 c 
ATOM   3329 H HB3  . LYS A 1 218 ? 18.153  -5.723  -13.037 1.000 26.393 0 233  LYS A HB3  1 c 
ATOM   3330 H HG2  . LYS A 1 218 ? 16.816  -7.894  -14.257 1.000 33.239 0 233  LYS A HG2  1 c 
ATOM   3331 H HG3  . LYS A 1 218 ? 18.348  -7.585  -14.505 1.000 33.440 0 233  LYS A HG3  1 c 
ATOM   3332 H HD2  . LYS A 1 218 ? 18.571  -7.816  -12.044 1.000 38.078 0 233  LYS A HD2  1 c 
ATOM   3333 H HD3  . LYS A 1 218 ? 17.170  -8.561  -12.131 1.000 38.422 0 233  LYS A HD3  1 c 
ATOM   3334 H HE2  . LYS A 1 218 ? 19.594  -9.429  -13.324 1.000 42.600 0 233  LYS A HE2  1 c 
ATOM   3335 H HE3  . LYS A 1 218 ? 18.787  -10.194 -12.207 1.000 42.513 0 233  LYS A HE3  1 c 
ATOM   3336 H HZ1  . LYS A 1 218 ? 18.117  -10.004 -14.841 1.000 46.053 0 233  LYS A HZ1  1 c 
ATOM   3337 H HZ2  . LYS A 1 218 ? 17.096  -10.388 -13.846 1.000 45.985 0 233  LYS A HZ2  1 c 
ATOM   3338 H HZ3  . LYS A 1 218 ? 18.285  -11.238 -14.049 1.000 46.022 0 233  LYS A HZ3  1 c 
ATOM   3339 N N    . MET A 1 219 ? 15.163  -3.712  -13.833 1.000 18.219 0 234  MET A N    1 ? 
ATOM   3340 C CA   . MET A 1 219 ? 14.809  -2.306  -13.916 1.000 17.169 0 234  MET A CA   1 ? 
ATOM   3341 C C    . MET A 1 219 ? 13.769  -1.937  -12.866 1.000 15.122 0 234  MET A C    1 ? 
ATOM   3342 O O    . MET A 1 219 ? 13.708  -0.791  -12.363 1.000 16.138 0 234  MET A O    1 ? 
ATOM   3343 C CB   . MET A 1 219 ? 14.295  -1.945  -15.329 1.000 18.363 0 234  MET A CB   1 ? 
ATOM   3344 C CG   . MET A 1 219 ? 15.352  -1.934  -16.399 1.000 21.257 0 234  MET A CG   1 ? 
ATOM   3345 S SD   . MET A 1 219 ? 14.641  -1.967  -18.063 1.000 23.641 0 234  MET A SD   1 ? 
ATOM   3346 C CE   . MET A 1 219 ? 13.984  -0.320  -18.122 1.000 24.275 0 234  MET A CE   1 ? 
ATOM   3347 H H    . MET A 1 219 ? 14.903  -4.273  -14.506 1.000 18.177 0 234  MET A H    1 c 
ATOM   3348 H HA   . MET A 1 219 ? 15.627  -1.778  -13.731 1.000 17.189 0 234  MET A HA   1 c 
ATOM   3349 H HB2  . MET A 1 219 ? 13.599  -2.590  -15.580 1.000 18.733 0 234  MET A HB2  1 c 
ATOM   3350 H HB3  . MET A 1 219 ? 13.878  -1.059  -15.290 1.000 18.726 0 234  MET A HB3  1 c 
ATOM   3351 H HG2  . MET A 1 219 ? 15.900  -1.130  -16.305 1.000 20.939 0 234  MET A HG2  1 c 
ATOM   3352 H HG3  . MET A 1 219 ? 15.935  -2.712  -16.289 1.000 20.934 0 234  MET A HG3  1 c 
ATOM   3353 H HE1  . MET A 1 219 ? 13.583  -0.161  -18.996 1.000 24.094 0 234  MET A HE1  1 c 
ATOM   3354 H HE2  . MET A 1 219 ? 13.306  -0.216  -17.429 1.000 24.037 0 234  MET A HE2  1 c 
ATOM   3355 H HE3  . MET A 1 219 ? 14.703  0.322   -17.973 1.000 24.094 0 234  MET A HE3  1 c 
ATOM   3356 N N    . GLU A 1 220 ? 12.909  -2.901  -12.488 1.000 15.178 0 235  GLU A N    1 ? 
ATOM   3357 C CA   . GLU A 1 220 ? 11.959  -2.687  -11.394 1.000 15.501 0 235  GLU A CA   1 ? 
ATOM   3358 C C    . GLU A 1 220 ? 12.665  -2.542  -10.046 1.000 16.347 0 235  GLU A C    1 ? 
ATOM   3359 O O    . GLU A 1 220 ? 12.285  -1.710  -9.218  1.000 14.999 0 235  GLU A O    1 ? 
ATOM   3360 C CB   . GLU A 1 220 ? 10.917  -3.788  -11.317 1.000 16.547 0 235  GLU A CB   1 ? 
ATOM   3361 C CG   . GLU A 1 220 ? 9.938   -3.766  -12.489 1.000 16.264 0 235  GLU A CG   1 ? 
ATOM   3362 C CD   . GLU A 1 220 ? 9.376   -5.076  -13.000 1.000 17.901 0 235  GLU A CD   1 ? 
ATOM   3363 O OE1  . GLU A 1 220 ? 9.625   -6.142  -12.345 1.000 16.469 0 235  GLU A OE1  1 ? 
ATOM   3364 O OE2  . GLU A 1 220 ? 8.654   -5.076  -14.011 1.000 17.761 0 235  GLU A OE2  1 ? 
ATOM   3365 H H    . GLU A 1 220 ? 12.907  -3.705  -12.924 1.000 15.276 0 235  GLU A H    1 c 
ATOM   3366 H HA   . GLU A 1 220 ? 11.477  -1.840  -11.576 1.000 15.778 0 235  GLU A HA   1 c 
ATOM   3367 H HB2  . GLU A 1 220 ? 11.375  -4.653  -11.291 1.000 16.249 0 235  GLU A HB2  1 c 
ATOM   3368 H HB3  . GLU A 1 220 ? 10.414  -3.691  -10.481 1.000 16.241 0 235  GLU A HB3  1 c 
ATOM   3369 H HG2  . GLU A 1 220 ? 9.179   -3.197  -12.239 1.000 16.692 0 235  GLU A HG2  1 c 
ATOM   3370 H HG3  . GLU A 1 220 ? 10.376  -3.320  -13.242 1.000 16.677 0 235  GLU A HG3  1 c 
ATOM   3371 N N    . VAL A 1 221 ? 13.770  -3.253  -9.863  1.000 15.397 0 236  VAL A N    1 ? 
ATOM   3372 C CA   . VAL A 1 221 ? 14.636  -2.975  -8.716  1.000 15.299 0 236  VAL A CA   1 ? 
ATOM   3373 C C    . VAL A 1 221 ? 15.241  -1.584  -8.806  1.000 14.966 0 236  VAL A C    1 ? 
ATOM   3374 O O    . VAL A 1 221 ? 15.257  -0.832  -7.807  1.000 15.213 0 236  VAL A O    1 ? 
ATOM   3375 C CB   . VAL A 1 221 ? 15.734  -4.055  -8.573  1.000 15.388 0 236  VAL A CB   1 ? 
ATOM   3376 C CG1  . VAL A 1 221 ? 16.637  -3.729  -7.395  1.000 18.689 0 236  VAL A CG1  1 ? 
ATOM   3377 C CG2  . VAL A 1 221 ? 15.128  -5.460  -8.446  1.000 16.354 0 236  VAL A CG2  1 ? 
ATOM   3378 H H    . VAL A 1 221 ? 13.998  -3.914  -10.452 1.000 15.600 0 236  VAL A H    1 c 
ATOM   3379 H HA   . VAL A 1 221 ? 14.082  -3.007  -7.912  1.000 15.287 0 236  VAL A HA   1 c 
ATOM   3380 H HB   . VAL A 1 221 ? 16.280  -4.029  -9.392  1.000 16.137 0 236  VAL A HB   1 c 
ATOM   3381 H HG11 . VAL A 1 221 ? 16.094  -3.504  -6.621  1.000 17.641 0 236  VAL A HG11 1 c 
ATOM   3382 H HG12 . VAL A 1 221 ? 17.208  -2.974  -7.619  1.000 17.628 0 236  VAL A HG12 1 c 
ATOM   3383 H HG13 . VAL A 1 221 ? 17.191  -4.500  -7.187  1.000 17.631 0 236  VAL A HG13 1 c 
ATOM   3384 H HG21 . VAL A 1 221 ? 15.835  -6.104  -8.273  1.000 16.077 0 236  VAL A HG21 1 c 
ATOM   3385 H HG22 . VAL A 1 221 ? 14.673  -5.696  -9.270  1.000 16.074 0 236  VAL A HG22 1 c 
ATOM   3386 H HG23 . VAL A 1 221 ? 14.492  -5.474  -7.711  1.000 16.069 0 236  VAL A HG23 1 c 
ATOM   3387 N N    . ALA A 1 222 ? 15.743  -1.181  -9.983  1.000 15.169 0 237  ALA A N    1 ? 
ATOM   3388 C CA   . ALA A 1 222 ? 16.278  0.179   -10.120 1.000 15.421 0 237  ALA A CA   1 ? 
ATOM   3389 C C    . ALA A 1 222 ? 15.200  1.232   -9.786  1.000 15.486 0 237  ALA A C    1 ? 
ATOM   3390 O O    . ALA A 1 222 ? 15.475  2.250   -9.164  1.000 14.856 0 237  ALA A O    1 ? 
ATOM   3391 C CB   . ALA A 1 222 ? 16.826  0.374   -11.526 1.000 16.501 0 237  ALA A CB   1 ? 
ATOM   3392 H H    . ALA A 1 222 ? 15.757  -1.747  -10.701 1.000 15.186 0 237  ALA A H    1 c 
ATOM   3393 H HA   . ALA A 1 222 ? 17.022  0.283   -9.467  1.000 15.592 0 237  ALA A HA   1 c 
ATOM   3394 H HB1  . ALA A 1 222 ? 17.523  -0.281  -11.699 1.000 16.175 0 237  ALA A HB1  1 c 
ATOM   3395 H HB2  . ALA A 1 222 ? 16.112  0.262   -12.175 1.000 16.175 0 237  ALA A HB2  1 c 
ATOM   3396 H HB3  . ALA A 1 222 ? 17.198  1.268   -11.610 1.000 16.175 0 237  ALA A HB3  1 c 
ATOM   3397 N N    . PHE A 1 223 ? 13.954  0.982   -10.188 1.000 14.584 0 238  PHE A N    1 ? 
ATOM   3398 C CA   . PHE A 1 223 ? 12.875  1.921   -9.875  1.000 14.997 0 238  PHE A CA   1 ? 
ATOM   3399 C C    . PHE A 1 223 ? 12.728  2.088   -8.360  1.000 15.436 0 238  PHE A C    1 ? 
ATOM   3400 O O    . PHE A 1 223 ? 12.588  3.197   -7.888  1.000 14.689 0 238  PHE A O    1 ? 
ATOM   3401 C CB   . PHE A 1 223 ? 11.575  1.506   -10.551 1.000 14.647 0 238  PHE A CB   1 ? 
ATOM   3402 C CG   . PHE A 1 223 ? 10.380  2.310   -10.092 1.000 14.760 0 238  PHE A CG   1 ? 
ATOM   3403 C CD1  . PHE A 1 223 ? 10.083  3.541   -10.684 1.000 15.056 0 238  PHE A CD1  1 ? 
ATOM   3404 C CD2  . PHE A 1 223 ? 9.565   1.844   -9.091  1.000 14.292 0 238  PHE A CD2  1 ? 
ATOM   3405 C CE1  . PHE A 1 223 ? 8.988   4.279   -10.266 1.000 14.332 0 238  PHE A CE1  1 ? 
ATOM   3406 C CE2  . PHE A 1 223 ? 8.482   2.596   -8.648  1.000 15.463 0 238  PHE A CE2  1 ? 
ATOM   3407 C CZ   . PHE A 1 223 ? 8.190   3.803   -9.235  1.000 15.533 0 238  PHE A CZ   1 ? 
ATOM   3408 H H    . PHE A 1 223 ? 13.766  0.227   -10.668 1.000 14.890 0 238  PHE A H    1 c 
ATOM   3409 H HA   . PHE A 1 223 ? 13.134  2.805   -10.249 1.000 14.931 0 238  PHE A HA   1 c 
ATOM   3410 H HB2  . PHE A 1 223 ? 11.678  1.613   -11.523 1.000 14.752 0 238  PHE A HB2  1 c 
ATOM   3411 H HB3  . PHE A 1 223 ? 11.413  0.555   -10.363 1.000 14.752 0 238  PHE A HB3  1 c 
ATOM   3412 H HD1  . PHE A 1 223 ? 10.631  3.867   -11.380 1.000 14.819 0 238  PHE A HD1  1 c 
ATOM   3413 H HD2  . PHE A 1 223 ? 9.764   1.021   -8.674  1.000 14.674 0 238  PHE A HD2  1 c 
ATOM   3414 H HE1  . PHE A 1 223 ? 8.798   5.112   -10.668 1.000 14.774 0 238  PHE A HE1  1 c 
ATOM   3415 H HE2  . PHE A 1 223 ? 7.930   2.263   -7.959  1.000 15.200 0 238  PHE A HE2  1 c 
ATOM   3416 H HZ   . PHE A 1 223 ? 7.442   4.301   -8.946  1.000 15.218 0 238  PHE A HZ   1 c 
ATOM   3417 N N    . MET A 1 224 ? 12.715  0.981   -7.600  1.000 15.734 0 239  MET A N    1 ? 
ATOM   3418 C CA   . MET A 1 224 ? 12.478  1.108   -6.167  1.000 15.442 0 239  MET A CA   1 ? 
ATOM   3419 C C    . MET A 1 224 ? 13.655  1.808   -5.483  1.000 15.338 0 239  MET A C    1 ? 
ATOM   3420 O O    . MET A 1 224 ? 13.476  2.499   -4.493  1.000 15.906 0 239  MET A O    1 ? 
ATOM   3421 C CB   . MET A 1 224 ? 12.209  -0.243  -5.491  1.000 16.793 0 239  MET A CB   1 ? 
ATOM   3422 C CG   . MET A 1 224 ? 13.416  -1.127  -5.229  1.000 15.433 0 239  MET A CG   1 ? 
ATOM   3423 S SD   . MET A 1 224 ? 12.980  -2.558  -4.196  1.000 17.217 0 239  MET A SD   1 ? 
ATOM   3424 C CE   . MET A 1 224 ? 12.474  -3.678  -5.492  1.000 17.146 0 239  MET A CE   1 ? 
ATOM   3425 H H    . MET A 1 224 ? 12.847  0.155   -7.968  1.000 15.594 0 239  MET A H    1 c 
ATOM   3426 H HA   . MET A 1 224 ? 11.679  1.683   -6.047  1.000 15.709 0 239  MET A HA   1 c 
ATOM   3427 H HB2  . MET A 1 224 ? 11.762  -0.070  -4.635  1.000 16.159 0 239  MET A HB2  1 c 
ATOM   3428 H HB3  . MET A 1 224 ? 11.578  -0.742  -6.052  1.000 16.159 0 239  MET A HB3  1 c 
ATOM   3429 H HG2  . MET A 1 224 ? 13.775  -1.449  -6.076  1.000 16.067 0 239  MET A HG2  1 c 
ATOM   3430 H HG3  . MET A 1 224 ? 14.113  -0.612  -4.777  1.000 16.061 0 239  MET A HG3  1 c 
ATOM   3431 H HE1  . MET A 1 224 ? 12.047  -4.460  -5.096  1.000 17.161 0 239  MET A HE1  1 c 
ATOM   3432 H HE2  . MET A 1 224 ? 11.843  -3.227  -6.083  1.000 17.170 0 239  MET A HE2  1 c 
ATOM   3433 H HE3  . MET A 1 224 ? 13.256  -3.960  -6.001  1.000 17.151 0 239  MET A HE3  1 c 
ATOM   3434 N N    . VAL A 1 225 ? 14.850  1.680   -6.054  1.000 14.473 0 240  VAL A N    1 ? 
ATOM   3435 C CA   . VAL A 1 225 ? 16.019  2.358   -5.530  1.000 13.851 0 240  VAL A CA   1 ? 
ATOM   3436 C C    . VAL A 1 225 ? 15.933  3.869   -5.813  1.000 15.344 0 240  VAL A C    1 ? 
ATOM   3437 O O    . VAL A 1 225 ? 16.137  4.718   -4.918  1.000 15.365 0 240  VAL A O    1 ? 
ATOM   3438 C CB   . VAL A 1 225 ? 17.287  1.710   -6.091  1.000 15.643 0 240  VAL A CB   1 ? 
ATOM   3439 C CG1  . VAL A 1 225 ? 18.485  2.563   -5.791  1.000 15.633 0 240  VAL A CG1  1 ? 
ATOM   3440 C CG2  . VAL A 1 225 ? 17.498  0.274   -5.580  1.000 15.722 0 240  VAL A CG2  1 ? 
ATOM   3441 H H    . VAL A 1 225 ? 14.945  1.143   -6.788  1.000 14.562 0 240  VAL A H    1 c 
ATOM   3442 H HA   . VAL A 1 225 ? 16.026  2.235   -4.561  1.000 14.569 0 240  VAL A HA   1 c 
ATOM   3443 H HB   . VAL A 1 225 ? 17.185  1.670   -7.071  1.000 15.300 0 240  VAL A HB   1 c 
ATOM   3444 H HG11 . VAL A 1 225 ? 18.455  2.853   -4.864  1.000 15.623 0 240  VAL A HG11 1 c 
ATOM   3445 H HG12 . VAL A 1 225 ? 18.487  3.342   -6.374  1.000 15.632 0 240  VAL A HG12 1 c 
ATOM   3446 H HG13 . VAL A 1 225 ? 19.296  2.048   -5.942  1.000 15.634 0 240  VAL A HG13 1 c 
ATOM   3447 H HG21 . VAL A 1 225 ? 18.298  -0.100  -5.984  1.000 15.698 0 240  VAL A HG21 1 c 
ATOM   3448 H HG22 . VAL A 1 225 ? 16.731  -0.272  -5.818  1.000 15.691 0 240  VAL A HG22 1 c 
ATOM   3449 H HG23 . VAL A 1 225 ? 17.598  0.286   -4.614  1.000 15.703 0 240  VAL A HG23 1 c 
ATOM   3450 N N    . CYS A 1 226 ? 15.585  4.243   -7.039  1.000 15.101 0 241  CYS A N    1 ? 
ATOM   3451 C CA   . CYS A 1 226 ? 15.294  5.635   -7.361  1.000 15.524 0 241  CYS A CA   1 ? 
ATOM   3452 C C    . CYS A 1 226 ? 14.183  6.217   -6.482  1.000 15.873 0 241  CYS A C    1 ? 
ATOM   3453 O O    . CYS A 1 226 ? 14.219  7.402   -6.158  1.000 16.192 0 241  CYS A O    1 ? 
ATOM   3454 C CB   . CYS A 1 226 ? 14.926  5.810   -8.840  1.000 14.600 0 241  CYS A CB   1 ? 
ATOM   3455 S SG   . CYS A 1 226 ? 16.344  5.502   -9.944  1.000 16.209 0 241  CYS A SG   1 ? 
ATOM   3456 H H    . CYS A 1 226 ? 15.529  3.616   -7.702  1.000 15.234 0 241  CYS A H    1 c 
ATOM   3457 H HA   . CYS A 1 226 ? 16.120  6.158   -7.196  1.000 15.330 0 241  CYS A HA   1 c 
ATOM   3458 H HB2  . CYS A 1 226 ? 14.203  5.187   -9.072  1.000 15.108 0 241  CYS A HB2  1 c 
ATOM   3459 H HB3  . CYS A 1 226 ? 14.602  6.726   -8.990  1.000 15.111 0 241  CYS A HB3  1 c 
ATOM   3460 H HG   . CYS A 1 226 ? 15.775  5.708   -10.996 0.000 16.180 0 241  CYS A HG   1 c 
ATOM   3461 N N    . ALA A 1 227 ? 13.213  5.375   -6.108  1.000 14.970 0 242  ALA A N    1 ? 
ATOM   3462 C CA   . ALA A 1 227 ? 12.068  5.770   -5.299  1.000 16.762 0 242  ALA A CA   1 ? 
ATOM   3463 C C    . ALA A 1 227 ? 12.420  5.996   -3.825  1.000 17.076 0 242  ALA A C    1 ? 
ATOM   3464 O O    . ALA A 1 227 ? 11.580  6.536   -3.133  1.000 16.566 0 242  ALA A O    1 ? 
ATOM   3465 C CB   . ALA A 1 227 ? 10.943  4.784   -5.412  1.000 15.427 0 242  ALA A CB   1 ? 
ATOM   3466 H H    . ALA A 1 227 ? 13.261  4.506   -6.386  1.000 15.567 0 242  ALA A H    1 c 
ATOM   3467 H HA   . ALA A 1 227 ? 11.744  6.642   -5.658  1.000 16.199 0 242  ALA A HA   1 c 
ATOM   3468 H HB1  . ALA A 1 227 ? 10.699  4.672   -6.346  1.000 15.819 0 242  ALA A HB1  1 c 
ATOM   3469 H HB2  . ALA A 1 227 ? 11.221  3.926   -5.049  1.000 15.819 0 242  ALA A HB2  1 c 
ATOM   3470 H HB3  . ALA A 1 227 ? 10.173  5.108   -4.916  1.000 15.835 0 242  ALA A HB3  1 c 
ATOM   3471 N N    . ILE A 1 228 ? 13.605  5.588   -3.367  1.000 16.613 0 243  ILE A N    1 ? 
ATOM   3472 C CA   . ILE A 1 228 ? 14.017  5.964   -2.017  1.000 17.539 0 243  ILE A CA   1 ? 
ATOM   3473 C C    . ILE A 1 228 ? 13.905  7.478   -1.862  1.000 17.368 0 243  ILE A C    1 ? 
ATOM   3474 O O    . ILE A 1 228 ? 14.285  8.219   -2.788  1.000 18.158 0 243  ILE A O    1 ? 
ATOM   3475 C CB   . ILE A 1 228 ? 15.451  5.468   -1.736  1.000 16.226 0 243  ILE A CB   1 ? 
ATOM   3476 C CG1  . ILE A 1 228 ? 15.570  3.957   -1.707  1.000 16.258 0 243  ILE A CG1  1 ? 
ATOM   3477 C CG2  . ILE A 1 228 ? 15.981  6.070   -0.436  1.000 18.338 0 243  ILE A CG2  1 ? 
ATOM   3478 C CD1  . ILE A 1 228 ? 17.003  3.454   -1.795  1.000 16.350 0 243  ILE A CD1  1 ? 
ATOM   3479 H H    . ILE A 1 228 ? 14.157  5.075   -3.883  1.000 16.883 0 243  ILE A H    1 c 
ATOM   3480 H HA   . ILE A 1 228 ? 13.412  5.537   -1.380  1.000 17.071 0 243  ILE A HA   1 c 
ATOM   3481 H HB   . ILE A 1 228 ? 16.019  5.791   -2.463  1.000 16.849 0 243  ILE A HB   1 c 
ATOM   3482 H HG12 . ILE A 1 228 ? 15.170  3.626   -0.877  1.000 16.273 0 243  ILE A HG12 1 c 
ATOM   3483 H HG13 . ILE A 1 228 ? 15.060  3.584   -2.454  1.000 16.277 0 243  ILE A HG13 1 c 
ATOM   3484 H HG21 . ILE A 1 228 ? 16.836  5.666   -0.212  1.000 17.673 0 243  ILE A HG21 1 c 
ATOM   3485 H HG22 . ILE A 1 228 ? 15.348  5.902   0.282   1.000 17.691 0 243  ILE A HG22 1 c 
ATOM   3486 H HG23 . ILE A 1 228 ? 16.099  7.029   -0.543  1.000 17.686 0 243  ILE A HG23 1 c 
ATOM   3487 H HD11 . ILE A 1 228 ? 17.446  3.863   -2.563  1.000 16.327 0 243  ILE A HD11 1 c 
ATOM   3488 H HD12 . ILE A 1 228 ? 16.999  2.484   -1.904  1.000 16.327 0 243  ILE A HD12 1 c 
ATOM   3489 H HD13 . ILE A 1 228 ? 17.488  3.685   -0.980  1.000 16.342 0 243  ILE A HD13 1 c 
ATOM   3490 N N    . ASN A 1 229 ? 13.364  7.927   -0.717  1.000 16.224 0 244  ASN A N    1 ? 
ATOM   3491 C CA   . ASN A 1 229 ? 13.213  9.348   -0.425  1.000 16.721 0 244  ASN A CA   1 ? 
ATOM   3492 C C    . ASN A 1 229 ? 14.024  9.662   0.825   1.000 18.860 0 244  ASN A C    1 ? 
ATOM   3493 O O    . ASN A 1 229 ? 13.590  9.403   1.941   1.000 19.772 0 244  ASN A O    1 ? 
ATOM   3494 C CB   . ASN A 1 229 ? 11.750  9.722   -0.328  1.000 18.209 0 244  ASN A CB   1 ? 
ATOM   3495 C CG   . ASN A 1 229 ? 11.553  11.212  -0.239  1.000 20.500 0 244  ASN A CG   1 ? 
ATOM   3496 O OD1  . ASN A 1 229 ? 12.503  11.941  0.075   1.000 22.195 0 244  ASN A OD1  1 ? 
ATOM   3497 N ND2  . ASN A 1 229 ? 10.321  11.668  -0.434  1.000 23.180 0 244  ASN A ND2  1 ? 
ATOM   3498 H H    . ASN A 1 229 ? 13.080  7.322   -0.094  1.000 16.630 0 244  ASN A H    1 c 
ATOM   3499 H HA   . ASN A 1 229 ? 13.586  9.856   -1.176  1.000 17.410 0 244  ASN A HA   1 c 
ATOM   3500 H HB2  . ASN A 1 229 ? 11.278  9.383   -1.115  1.000 18.354 0 244  ASN A HB2  1 c 
ATOM   3501 H HB3  . ASN A 1 229 ? 11.361  9.300   0.463   1.000 18.364 0 244  ASN A HB3  1 c 
ATOM   3502 H HD21 . ASN A 1 229 ? 9.659   11.102  -0.599  1.000 22.286 0 244  ASN A HD21 1 c 
ATOM   3503 H HD22 . ASN A 1 229 ? 10.163  12.540  -0.398  1.000 22.311 0 244  ASN A HD22 1 c 
ATOM   3504 N N    . PRO A 1 230 ? 15.250  10.189  0.666   1.000 20.967 0 245  PRO A N    1 ? 
ATOM   3505 C CA   . PRO A 1 230 ? 16.071  10.570  1.822   1.000 22.221 0 245  PRO A CA   1 ? 
ATOM   3506 C C    . PRO A 1 230 ? 15.584  11.740  2.669   1.000 23.636 0 245  PRO A C    1 ? 
ATOM   3507 O O    . PRO A 1 230 ? 16.161  11.980  3.748   1.000 23.472 0 245  PRO A O    1 ? 
ATOM   3508 C CB   . PRO A 1 230 ? 17.404  10.901  1.151   1.000 21.921 0 245  PRO A CB   1 ? 
ATOM   3509 C CG   . PRO A 1 230 ? 17.317  10.337  -0.222  1.000 27.390 0 245  PRO A CG   1 ? 
ATOM   3510 C CD   . PRO A 1 230 ? 15.863  10.555  -0.617  1.000 24.029 0 245  PRO A CD   1 ? 
ATOM   3511 H HA   . PRO A 1 230 ? 16.187  9.774   2.398   1.000 22.123 0 245  PRO A HA   1 c 
ATOM   3512 H HB2  . PRO A 1 230 ? 17.546  11.876  1.117   1.000 23.153 0 245  PRO A HB2  1 c 
ATOM   3513 H HB3  . PRO A 1 230 ? 18.153  10.495  1.647   1.000 23.150 0 245  PRO A HB3  1 c 
ATOM   3514 H HG2  . PRO A 1 230 ? 17.920  10.808  -0.834  1.000 25.255 0 245  PRO A HG2  1 c 
ATOM   3515 H HG3  . PRO A 1 230 ? 17.541  9.383   -0.224  1.000 25.266 0 245  PRO A HG3  1 c 
ATOM   3516 H HD2  . PRO A 1 230 ? 15.684  11.491  -0.857  1.000 23.937 0 245  PRO A HD2  1 c 
ATOM   3517 H HD3  . PRO A 1 230 ? 15.594  9.953   -1.344  1.000 23.819 0 245  PRO A HD3  1 c 
ATOM   3518 N N    . SER A 1 231 ? 14.537  12.450  2.239   1.000 22.971 0 246  SER A N    1 ? 
ATOM   3519 C CA   . SER A 1 231 ? 14.141  13.682  2.917   1.000 25.156 0 246  SER A CA   1 ? 
ATOM   3520 C C    . SER A 1 231 ? 13.591  13.422  4.306   1.000 26.694 0 246  SER A C    1 ? 
ATOM   3521 O O    . SER A 1 231 ? 12.672  12.639  4.498   1.000 26.241 0 246  SER A O    1 ? 
ATOM   3522 C CB   . SER A 1 231 ? 13.162  14.507  2.099   1.000 29.783 0 246  SER A CB   1 ? 
ATOM   3523 O OG   . SER A 1 231 ? 13.834  14.915  0.919   1.000 37.518 0 246  SER A OG   1 ? 
ATOM   3524 H H    . SER A 1 231 ? 14.062  12.174  1.509   1.000 23.578 0 246  SER A H    1 c 
ATOM   3525 H HA   . SER A 1 231 ? 14.960  14.226  3.025   1.000 25.791 0 246  SER A HA   1 c 
ATOM   3526 H HB2  . SER A 1 231 ? 12.381  13.967  1.871   1.000 30.259 0 246  SER A HB2  1 c 
ATOM   3527 H HB3  . SER A 1 231 ? 12.876  15.288  2.610   1.000 30.281 0 246  SER A HB3  1 c 
ATOM   3528 H HG   . SER A 1 231 ? 13.334  15.385  0.447   0.000 37.350 0 246  SER A HG   1 c 
ATOM   3529 N N    . ILE A 1 232 ? 14.137  14.141  5.306   1.000 24.345 0 247  ILE A N    1 ? 
ATOM   3530 C CA   . ILE A 1 232 ? 13.592  14.061  6.651   1.000 25.820 0 247  ILE A CA   1 ? 
ATOM   3531 C C    . ILE A 1 232 ? 12.557  15.183  6.800   1.000 29.402 0 247  ILE A C    1 ? 
ATOM   3532 O O    . ILE A 1 232 ? 11.433  14.971  7.271   1.000 30.328 0 247  ILE A O    1 ? 
ATOM   3533 C CB   . ILE A 1 232 ? 14.720  14.161  7.687   1.000 26.316 0 247  ILE A CB   1 ? 
ATOM   3534 C CG1  . ILE A 1 232 ? 15.619  12.918  7.666   1.000 26.621 0 247  ILE A CG1  1 ? 
ATOM   3535 C CG2  . ILE A 1 232 ? 14.127  14.425  9.069   1.000 28.884 0 247  ILE A CG2  1 ? 
ATOM   3536 C CD1  . ILE A 1 232 ? 16.949  13.056  8.411   1.000 28.454 0 247  ILE A CD1  1 ? 
ATOM   3537 H H    . ILE A 1 232 ? 14.859  14.679  5.146   1.000 25.293 0 247  ILE A H    1 c 
ATOM   3538 H HA   . ILE A 1 232 ? 13.143  13.201  6.762   1.000 26.233 0 247  ILE A HA   1 c 
ATOM   3539 H HB   . ILE A 1 232 ? 15.274  14.930  7.449   1.000 26.731 0 247  ILE A HB   1 c 
ATOM   3540 H HG12 . ILE A 1 232 ? 15.123  12.172  8.058   1.000 26.896 0 247  ILE A HG12 1 c 
ATOM   3541 H HG13 . ILE A 1 232 ? 15.810  12.687  6.734   1.000 26.932 0 247  ILE A HG13 1 c 
ATOM   3542 H HG21 . ILE A 1 232 ? 14.811  14.294  9.748   1.000 28.107 0 247  ILE A HG21 1 c 
ATOM   3543 H HG22 . ILE A 1 232 ? 13.392  13.810  9.232   1.000 28.111 0 247  ILE A HG22 1 c 
ATOM   3544 H HG23 . ILE A 1 232 ? 13.801  15.339  9.117   1.000 28.113 0 247  ILE A HG23 1 c 
ATOM   3545 H HD11 . ILE A 1 232 ? 17.446  13.816  8.053   1.000 27.905 0 247  ILE A HD11 1 c 
ATOM   3546 H HD12 . ILE A 1 232 ? 17.473  12.242  8.295   1.000 27.904 0 247  ILE A HD12 1 c 
ATOM   3547 H HD13 . ILE A 1 232 ? 16.781  13.199  9.362   1.000 27.906 0 247  ILE A HD13 1 c 
ATOM   3548 N N    . ASP A 1 233 ? 12.929  16.360  6.306   1.000 33.374 0 248  ASP A N    1 ? 
ATOM   3549 C CA   . ASP A 1 233 ? 12.009  17.479  6.233   1.000 34.982 0 248  ASP A CA   1 ? 
ATOM   3550 C C    . ASP A 1 233 ? 12.436  18.322  5.048   1.000 37.358 0 248  ASP A C    1 ? 
ATOM   3551 O O    . ASP A 1 233 ? 13.321  17.920  4.293   1.000 36.827 0 248  ASP A O    1 ? 
ATOM   3552 C CB   . ASP A 1 233 ? 11.943  18.229  7.555   1.000 35.029 0 248  ASP A CB   1 ? 
ATOM   3553 C CG   . ASP A 1 233 ? 13.269  18.750  8.101   1.000 34.065 0 248  ASP A CG   1 ? 
ATOM   3554 O OD1  . ASP A 1 233 ? 14.105  19.271  7.320   1.000 36.608 0 248  ASP A OD1  1 ? 
ATOM   3555 O OD2  . ASP A 1 233 ? 13.456  18.650  9.318   1.000 43.406 0 248  ASP A OD2  1 ? 
ATOM   3556 H H    . ASP A 1 233 ? 13.790  16.479  6.022   1.000 32.566 0 248  ASP A H    1 c 
ATOM   3557 H HA   . ASP A 1 233 ? 11.108  17.126  6.049   1.000 35.034 0 248  ASP A HA   1 c 
ATOM   3558 H HB2  . ASP A 1 233 ? 11.328  18.986  7.473   1.000 34.859 0 248  ASP A HB2  1 c 
ATOM   3559 H HB3  . ASP A 1 233 ? 11.567  17.620  8.225   1.000 34.854 0 248  ASP A HB3  1 c 
ATOM   3560 N N    . LEU A 1 234 ? 11.834  19.509  4.921   1.000 38.754 0 249  LEU A N    1 ? 
ATOM   3561 C CA   . LEU A 1 234 ? 12.081  20.346  3.754   1.000 41.865 0 249  LEU A CA   1 ? 
ATOM   3562 C C    . LEU A 1 234 ? 13.524  20.874  3.745   1.000 36.907 0 249  LEU A C    1 ? 
ATOM   3563 O O    . LEU A 1 234 ? 14.011  21.249  2.689   1.000 42.645 0 249  LEU A O    1 ? 
ATOM   3564 C CB   . LEU A 1 234 ? 11.016  21.452  3.712   1.000 47.306 0 249  LEU A CB   1 ? 
ATOM   3565 C CG   . LEU A 1 234 ? 9.543   21.005  3.611   1.000 53.667 0 249  LEU A CG   1 ? 
ATOM   3566 C CD1  . LEU A 1 234 ? 8.573   22.167  3.882   1.000 54.554 0 249  LEU A CD1  1 ? 
ATOM   3567 C CD2  . LEU A 1 234 ? 9.183   20.365  2.264   1.000 52.449 0 249  LEU A CD2  1 ? 
ATOM   3568 H H    . LEU A 1 234 ? 11.258  19.804  5.565   1.000 39.195 0 249  LEU A H    1 c 
ATOM   3569 H HA   . LEU A 1 234 ? 11.969  19.777  2.950   1.000 41.220 0 249  LEU A HA   1 c 
ATOM   3570 H HB2  . LEU A 1 234 ? 11.115  22.001  4.524   1.000 47.338 0 249  LEU A HB2  1 c 
ATOM   3571 H HB3  . LEU A 1 234 ? 11.214  22.036  2.944   1.000 47.338 0 249  LEU A HB3  1 c 
ATOM   3572 H HG   . LEU A 1 234 ? 9.386   20.322  4.312   1.000 52.186 0 249  LEU A HG   1 c 
ATOM   3573 H HD11 . LEU A 1 234 ? 8.802   22.590  4.726   1.000 54.292 0 249  LEU A HD11 1 c 
ATOM   3574 H HD12 . LEU A 1 234 ? 7.663   21.828  3.925   1.000 54.293 0 249  LEU A HD12 1 c 
ATOM   3575 H HD13 . LEU A 1 234 ? 8.641   22.820  3.165   1.000 54.293 0 249  LEU A HD13 1 c 
ATOM   3576 H HD21 . LEU A 1 234 ? 9.734   19.577  2.120   1.000 52.713 0 249  LEU A HD21 1 c 
ATOM   3577 H HD22 . LEU A 1 234 ? 9.339   21.003  1.548   1.000 52.781 0 249  LEU A HD22 1 c 
ATOM   3578 H HD23 . LEU A 1 234 ? 8.246   20.106  2.267   1.000 52.781 0 249  LEU A HD23 1 c 
ATOM   3579 N N    . HIS A 1 235 ? 14.240  20.817  4.886   1.000 44.256 0 250  HIS A N    1 ? 
ATOM   3580 C CA   . HIS A 1 235 ? 15.585  21.371  5.004   1.000 47.057 0 250  HIS A CA   1 ? 
ATOM   3581 C C    . HIS A 1 235 ? 16.663  20.318  5.306   1.000 46.579 0 250  HIS A C    1 ? 
ATOM   3582 O O    . HIS A 1 235 ? 17.836  20.667  5.424   1.000 43.739 0 250  HIS A O    1 ? 
ATOM   3583 C CB   . HIS A 1 235 ? 15.598  22.471  6.077   1.000 46.762 0 250  HIS A CB   1 ? 
ATOM   3584 H H    . HIS A 1 235 ? 13.867  20.432  5.625   1.000 42.842 0 250  HIS A H    1 c 
ATOM   3585 H HA   . HIS A 1 235 ? 15.813  21.796  4.141   1.000 46.272 0 250  HIS A HA   1 c 
ATOM   3586 H HB2  . HIS A 1 235 ? 15.391  22.064  6.947   1.000 46.848 0 250  HIS A HB2  1 c 
ATOM   3587 H HB3  . HIS A 1 235 ? 16.510  22.802  6.190   0.000 47.070 0 250  HIS A HB3  1 c 
ATOM   3588 N N    . THR A 1 236 ? 16.318  19.027  5.432   1.000 35.640 0 251  THR A N    1 ? 
ATOM   3589 C CA   . THR A 1 236 ? 17.281  18.058  5.937   1.000 31.310 0 251  THR A CA   1 ? 
ATOM   3590 C C    . THR A 1 236 ? 17.092  16.726  5.207   1.000 29.368 0 251  THR A C    1 ? 
ATOM   3591 O O    . THR A 1 236 ? 15.957  16.265  5.144   1.000 28.462 0 251  THR A O    1 ? 
ATOM   3592 C CB   . THR A 1 236 ? 17.058  17.842  7.426   1.000 36.582 0 251  THR A CB   1 ? 
ATOM   3593 O OG1  . THR A 1 236 ? 16.994  19.128  8.050   1.000 42.865 0 251  THR A OG1  1 ? 
ATOM   3594 C CG2  . THR A 1 236 ? 18.173  17.011  8.041   1.000 38.267 0 251  THR A CG2  1 ? 
ATOM   3595 H H    . THR A 1 236 ? 15.480  18.747  5.199   1.000 36.953 0 251  THR A H    1 c 
ATOM   3596 H HA   . THR A 1 236 ? 18.191  18.391  5.788   1.000 32.754 0 251  THR A HA   1 c 
ATOM   3597 H HB   . THR A 1 236 ? 16.200  17.374  7.564   1.000 36.887 0 251  THR A HB   1 c 
ATOM   3598 H HG1  . THR A 1 236 ? 17.735  19.547  7.927   0.000 42.690 0 251  THR A HG1  1 c 
ATOM   3599 H HG21 . THR A 1 236 ? 18.061  16.984  9.006   1.000 37.749 0 251  THR A HG21 1 c 
ATOM   3600 H HG22 . THR A 1 236 ? 19.032  17.412  7.826   1.000 37.750 0 251  THR A HG22 1 c 
ATOM   3601 H HG23 . THR A 1 236 ? 18.140  16.107  7.687   1.000 37.713 0 251  THR A HG23 1 c 
ATOM   3602 N N    . ASP A 1 237 ? 18.193  16.153  4.713   1.000 27.265 0 252  ASP A N    1 ? 
ATOM   3603 C CA   . ASP A 1 237 ? 18.175  14.808  4.155   1.000 27.492 0 252  ASP A CA   1 ? 
ATOM   3604 C C    . ASP A 1 237 ? 18.933  13.859  5.071   1.000 27.612 0 252  ASP A C    1 ? 
ATOM   3605 O O    . ASP A 1 237 ? 19.912  14.222  5.727   1.000 28.453 0 252  ASP A O    1 ? 
ATOM   3606 C CB   . ASP A 1 237 ? 18.782  14.771  2.768   1.000 30.265 0 252  ASP A CB   1 ? 
ATOM   3607 C CG   . ASP A 1 237 ? 17.961  15.444  1.686   1.000 34.015 0 252  ASP A CG   1 ? 
ATOM   3608 O OD1  . ASP A 1 237 ? 16.734  15.585  1.855   1.000 33.818 0 252  ASP A OD1  1 ? 
ATOM   3609 O OD2  . ASP A 1 237 ? 18.578  15.869  0.704   1.000 46.979 0 252  ASP A OD2  1 ? 
ATOM   3610 H H    . ASP A 1 237 ? 18.982  16.614  4.721   1.000 27.867 0 252  ASP A H    1 c 
ATOM   3611 H HA   . ASP A 1 237 ? 17.241  14.505  4.093   1.000 27.964 0 252  ASP A HA   1 c 
ATOM   3612 H HB2  . ASP A 1 237 ? 19.660  15.204  2.799   1.000 30.493 0 252  ASP A HB2  1 c 
ATOM   3613 H HB3  . ASP A 1 237 ? 18.917  13.836  2.507   1.000 30.415 0 252  ASP A HB3  1 c 
ATOM   3614 N N    . SER A 1 238 ? 18.528  12.582  5.052   1.000 21.659 0 253  SER A N    1 ? 
ATOM   3615 C CA   . SER A 1 238 ? 19.260  11.527  5.716   1.000 21.154 0 253  SER A CA   1 ? 
ATOM   3616 C C    . SER A 1 238 ? 20.526  11.186  4.938   1.000 23.502 0 253  SER A C    1 ? 
ATOM   3617 O O    . SER A 1 238 ? 20.470  10.721  3.804   1.000 21.083 0 253  SER A O    1 ? 
ATOM   3618 C CB   . SER A 1 238 ? 18.420  10.281  5.850   1.000 19.227 0 253  SER A CB   1 ? 
ATOM   3619 O OG   . SER A 1 238 ? 19.201  9.136   6.182   1.000 20.056 0 253  SER A OG   1 ? 
ATOM   3620 H H    . SER A 1 238 ? 17.761  12.367  4.603   1.000 22.845 0 253  SER A H    1 c 
ATOM   3621 H HA   . SER A 1 238 ? 19.514  11.839  6.621   1.000 21.365 0 253  SER A HA   1 c 
ATOM   3622 H HB2  . SER A 1 238 ? 17.747  10.423  6.543   1.000 19.848 0 253  SER A HB2  1 c 
ATOM   3623 H HB3  . SER A 1 238 ? 17.954  10.118  5.009   1.000 19.857 0 253  SER A HB3  1 c 
ATOM   3624 H HG   . SER A 1 238 ? 18.687  8.467   6.244   0.000 20.040 0 253  SER A HG   1 c 
ATOM   3625 N N    . LEU A 1 239 ? 21.680  11.364  5.572   1.000 22.849 0 254  LEU A N    1 ? 
ATOM   3626 C CA   . LEU A 1 239 ? 22.937  10.997  4.944   1.000 22.090 0 254  LEU A CA   1 ? 
ATOM   3627 C C    . LEU A 1 239 ? 22.982  9.499   4.686   1.000 21.417 0 254  LEU A C    1 ? 
ATOM   3628 O O    . LEU A 1 239 ? 23.601  9.082   3.716   1.000 21.498 0 254  LEU A O    1 ? 
ATOM   3629 C CB   . LEU A 1 239 ? 24.128  11.436  5.803   1.000 21.813 0 254  LEU A CB   1 ? 
ATOM   3630 C CG   . LEU A 1 239 ? 24.257  12.955  5.975   1.000 26.647 0 254  LEU A CG   1 ? 
ATOM   3631 C CD1  . LEU A 1 239 ? 25.461  13.234  6.876   1.000 28.859 0 254  LEU A CD1  1 ? 
ATOM   3632 C CD2  . LEU A 1 239 ? 24.374  13.711  4.670   1.000 32.584 0 254  LEU A CD2  1 ? 
ATOM   3633 H H    . LEU A 1 239 ? 21.690  11.720  6.414   1.000 22.845 0 254  LEU A H    1 c 
ATOM   3634 H HA   . LEU A 1 239 ? 22.987  11.457  4.069   1.000 22.152 0 254  LEU A HA   1 c 
ATOM   3635 H HB2  . LEU A 1 239 ? 24.037  11.026  6.694   1.000 22.892 0 254  LEU A HB2  1 c 
ATOM   3636 H HB3  . LEU A 1 239 ? 24.954  11.096  5.387   1.000 22.886 0 254  LEU A HB3  1 c 
ATOM   3637 H HG   . LEU A 1 239 ? 23.446  13.280  6.443   1.000 27.015 0 254  LEU A HG   1 c 
ATOM   3638 H HD11 . LEU A 1 239 ? 25.326  12.810  7.740   1.000 28.195 0 254  LEU A HD11 1 c 
ATOM   3639 H HD12 . LEU A 1 239 ? 25.560  14.193  6.999   1.000 28.207 0 254  LEU A HD12 1 c 
ATOM   3640 H HD13 . LEU A 1 239 ? 26.266  12.877  6.464   1.000 28.195 0 254  LEU A HD13 1 c 
ATOM   3641 H HD21 . LEU A 1 239 ? 23.522  13.688  4.202   1.000 30.567 0 254  LEU A HD21 1 c 
ATOM   3642 H HD22 . LEU A 1 239 ? 25.059  13.300  4.116   1.000 30.660 0 254  LEU A HD22 1 c 
ATOM   3643 H HD23 . LEU A 1 239 ? 24.617  14.635  4.851   1.000 30.646 0 254  LEU A HD23 1 c 
ATOM   3644 N N    . GLU A 1 240 ? 22.398  8.721   5.603   1.000 19.407 0 255  GLU A N    1 ? 
ATOM   3645 C CA   . GLU A 1 240 ? 22.423  7.284   5.538   1.000 18.611 0 255  GLU A CA   1 ? 
ATOM   3646 C C    . GLU A 1 240 ? 21.646  6.865   4.277   1.000 19.020 0 255  GLU A C    1 ? 
ATOM   3647 O O    . GLU A 1 240 ? 22.091  5.998   3.541   1.000 19.033 0 255  GLU A O    1 ? 
ATOM   3648 C CB   . GLU A 1 240 ? 21.863  6.607   6.799   1.000 19.193 0 255  GLU A CB   1 ? 
ATOM   3649 C CG   . GLU A 1 240 ? 22.474  7.111   8.113   1.000 21.962 0 255  GLU A CG   1 ? 
ATOM   3650 C CD   . GLU A 1 240 ? 21.774  8.306   8.773   1.000 22.900 0 255  GLU A CD   1 ? 
ATOM   3651 O OE1  . GLU A 1 240 ? 20.984  9.080   8.154   1.000 23.187 0 255  GLU A OE1  1 ? 
ATOM   3652 O OE2  . GLU A 1 240 ? 22.026  8.444   10.040  1.000 25.210 0 255  GLU A OE2  1 ? 
ATOM   3653 H H    . GLU A 1 240 ? 21.958  9.116   6.300   1.000 19.760 0 255  GLU A H    1 c 
ATOM   3654 H HA   . GLU A 1 240 ? 23.366  7.000   5.431   1.000 18.968 0 255  GLU A HA   1 c 
ATOM   3655 H HB2  . GLU A 1 240 ? 20.895  6.754   6.829   1.000 19.701 0 255  GLU A HB2  1 c 
ATOM   3656 H HB3  . GLU A 1 240 ? 22.014  5.641   6.731   1.000 19.662 0 255  GLU A HB3  1 c 
ATOM   3657 H HG2  . GLU A 1 240 ? 22.484  6.371   8.757   1.000 21.521 0 255  GLU A HG2  1 c 
ATOM   3658 H HG3  . GLU A 1 240 ? 23.408  7.359   7.948   1.000 21.589 0 255  GLU A HG3  1 c 
ATOM   3659 N N    . LEU A 1 241 ? 20.509  7.514   4.016   1.000 18.098 0 256  LEU A N    1 ? 
ATOM   3660 C CA   . LEU A 1 241 ? 19.699  7.099   2.879   1.000 18.713 0 256  LEU A CA   1 ? 
ATOM   3661 C C    . LEU A 1 241 ? 20.316  7.575   1.567   1.000 18.558 0 256  LEU A C    1 ? 
ATOM   3662 O O    . LEU A 1 241 ? 20.250  6.848   0.578   1.000 19.310 0 256  LEU A O    1 ? 
ATOM   3663 C CB   . LEU A 1 241 ? 18.263  7.576   3.024   1.000 18.245 0 256  LEU A CB   1 ? 
ATOM   3664 C CG   . LEU A 1 241 ? 17.456  6.822   4.092   1.000 20.123 0 256  LEU A CG   1 ? 
ATOM   3665 C CD1  . LEU A 1 241 ? 16.190  7.604   4.281   1.000 19.364 0 256  LEU A CD1  1 ? 
ATOM   3666 C CD2  . LEU A 1 241 ? 17.180  5.373   3.681   1.000 20.670 0 256  LEU A CD2  1 ? 
ATOM   3667 H H    . LEU A 1 241 ? 20.231  8.208   4.542   1.000 18.460 0 256  LEU A H    1 c 
ATOM   3668 H HA   . LEU A 1 241 ? 19.698  6.109   2.860   1.000 18.511 0 256  LEU A HA   1 c 
ATOM   3669 H HB2  . LEU A 1 241 ? 18.277  8.533   3.254   1.000 18.775 0 256  LEU A HB2  1 c 
ATOM   3670 H HB3  . LEU A 1 241 ? 17.811  7.470   2.156   1.000 18.763 0 256  LEU A HB3  1 c 
ATOM   3671 H HG   . LEU A 1 241 ? 17.968  6.826   4.942   1.000 19.719 0 256  LEU A HG   1 c 
ATOM   3672 H HD11 . LEU A 1 241 ? 16.401  8.490   4.620   1.000 19.586 0 256  LEU A HD11 1 c 
ATOM   3673 H HD12 . LEU A 1 241 ? 15.616  7.144   4.917   1.000 19.589 0 256  LEU A HD12 1 c 
ATOM   3674 H HD13 . LEU A 1 241 ? 15.728  7.685   3.430   1.000 19.595 0 256  LEU A HD13 1 c 
ATOM   3675 H HD21 . LEU A 1 241 ? 18.017  4.881   3.638   1.000 20.477 0 256  LEU A HD21 1 c 
ATOM   3676 H HD22 . LEU A 1 241 ? 16.752  5.359   2.808   1.000 20.496 0 256  LEU A HD22 1 c 
ATOM   3677 H HD23 . LEU A 1 241 ? 16.595  4.956   4.335   1.000 20.478 0 256  LEU A HD23 1 c 
ATOM   3678 N N    . LEU A 1 242 ? 20.915  8.753   1.553   1.000 18.701 0 257  LEU A N    1 ? 
ATOM   3679 C CA   . LEU A 1 242 ? 21.660  9.213   0.383   1.000 19.274 0 257  LEU A CA   1 ? 
ATOM   3680 C C    . LEU A 1 242 ? 22.745  8.212   0.007   1.000 19.851 0 257  LEU A C    1 ? 
ATOM   3681 O O    . LEU A 1 242 ? 22.905  7.824   -1.162  1.000 18.082 0 257  LEU A O    1 ? 
ATOM   3682 C CB   . LEU A 1 242 ? 22.259  10.599  0.649   1.000 20.171 0 257  LEU A CB   1 ? 
ATOM   3683 C CG   . LEU A 1 242 ? 21.266  11.762  0.675   1.000 21.813 0 257  LEU A CG   1 ? 
ATOM   3684 C CD1  . LEU A 1 242 ? 21.915  13.002  1.285   1.000 23.529 0 257  LEU A CD1  1 ? 
ATOM   3685 C CD2  . LEU A 1 242 ? 20.725  12.089  -0.709  1.000 24.070 0 257  LEU A CD2  1 ? 
ATOM   3686 H H    . LEU A 1 242 ? 20.858  9.299   2.284   1.000 18.808 0 257  LEU A H    1 c 
ATOM   3687 H HA   . LEU A 1 242 ? 21.027  9.278   -0.375  1.000 19.467 0 257  LEU A HA   1 c 
ATOM   3688 H HB2  . LEU A 1 242 ? 22.727  10.570  1.515   1.000 20.344 0 257  LEU A HB2  1 c 
ATOM   3689 H HB3  . LEU A 1 242 ? 22.932  10.782  -0.047  1.000 20.324 0 257  LEU A HB3  1 c 
ATOM   3690 H HG   . LEU A 1 242 ? 20.501  11.502  1.250   1.000 22.202 0 257  LEU A HG   1 c 
ATOM   3691 H HD11 . LEU A 1 242 ? 22.197  12.807  2.195   1.000 22.991 0 257  LEU A HD11 1 c 
ATOM   3692 H HD12 . LEU A 1 242 ? 21.274  13.732  1.295   1.000 23.006 0 257  LEU A HD12 1 c 
ATOM   3693 H HD13 . LEU A 1 242 ? 22.689  13.257  0.755   1.000 23.006 0 257  LEU A HD13 1 c 
ATOM   3694 H HD21 . LEU A 1 242 ? 20.231  11.327  -1.055  1.000 23.362 0 257  LEU A HD21 1 c 
ATOM   3695 H HD22 . LEU A 1 242 ? 21.463  12.294  -1.307  1.000 23.376 0 257  LEU A HD22 1 c 
ATOM   3696 H HD23 . LEU A 1 242 ? 20.133  12.858  -0.653  1.000 23.376 0 257  LEU A HD23 1 c 
ATOM   3697 N N    . GLN A 1 243 ? 23.527  7.769   1.008   1.000 20.841 0 258  GLN A N    1 ? 
ATOM   3698 C CA   . GLN A 1 243 ? 24.602  6.804   0.779   1.000 20.005 0 258  GLN A CA   1 ? 
ATOM   3699 C C    . GLN A 1 243 ? 24.041  5.464   0.270   1.000 20.924 0 258  GLN A C    1 ? 
ATOM   3700 O O    . GLN A 1 243 ? 24.616  4.833   -0.613  1.000 21.185 0 258  GLN A O    1 ? 
ATOM   3701 C CB   . GLN A 1 243 ? 25.520  6.616   2.002   1.000 21.120 0 258  GLN A CB   1 ? 
ATOM   3702 C CG   . GLN A 1 243 ? 26.640  5.588   1.814   1.000 25.272 0 258  GLN A CG   1 ? 
ATOM   3703 C CD   . GLN A 1 243 ? 27.382  5.183   3.085   1.000 28.597 0 258  GLN A CD   1 ? 
ATOM   3704 O OE1  . GLN A 1 243 ? 27.666  4.003   3.354   1.000 33.309 0 258  GLN A OE1  1 ? 
ATOM   3705 N NE2  . GLN A 1 243 ? 27.694  6.170   3.901   1.000 33.316 0 258  GLN A NE2  1 ? 
ATOM   3706 H H    . GLN A 1 243 ? 23.390  8.080   1.856   1.000 20.397 0 258  GLN A H    1 c 
ATOM   3707 H HA   . GLN A 1 243 ? 25.175  7.173   0.059   1.000 20.520 0 258  GLN A HA   1 c 
ATOM   3708 H HB2  . GLN A 1 243 ? 25.923  7.482   2.223   1.000 21.734 0 258  GLN A HB2  1 c 
ATOM   3709 H HB3  . GLN A 1 243 ? 24.968  6.345   2.765   1.000 21.734 0 258  GLN A HB3  1 c 
ATOM   3710 H HG2  . GLN A 1 243 ? 26.264  4.775   1.416   1.000 24.937 0 258  GLN A HG2  1 c 
ATOM   3711 H HG3  . GLN A 1 243 ? 27.296  5.947   1.180   1.000 25.040 0 258  GLN A HG3  1 c 
ATOM   3712 H HE21 . GLN A 1 243 ? 27.933  6.959   3.572   1.000 31.663 0 258  GLN A HE21 1 c 
ATOM   3713 H HE22 . GLN A 1 243 ? 27.665  6.044   4.779   1.000 31.756 0 258  GLN A HE22 1 c 
ATOM   3714 N N    . LEU A 1 244 ? 22.965  4.976   0.885   1.000 19.684 0 259  LEU A N    1 ? 
ATOM   3715 C CA   . LEU A 1 244 ? 22.348  3.718   0.491   1.000 19.174 0 259  LEU A CA   1 ? 
ATOM   3716 C C    . LEU A 1 244 ? 21.873  3.809   -0.965  1.000 18.130 0 259  LEU A C    1 ? 
ATOM   3717 O O    . LEU A 1 244 ? 22.161  2.896   -1.741  1.000 17.297 0 259  LEU A O    1 ? 
ATOM   3718 C CB   . LEU A 1 244 ? 21.190  3.382   1.417   1.000 19.835 0 259  LEU A CB   1 ? 
ATOM   3719 C CG   . LEU A 1 244 ? 20.423  2.106   1.060   1.000 19.626 0 259  LEU A CG   1 ? 
ATOM   3720 C CD1  . LEU A 1 244 ? 21.303  0.856   1.090   1.000 20.278 0 259  LEU A CD1  1 ? 
ATOM   3721 C CD2  . LEU A 1 244 ? 19.236  1.969   1.970   1.000 19.631 0 259  LEU A CD2  1 ? 
ATOM   3722 H H    . LEU A 1 244 ? 22.601  5.442   1.582   1.000 19.862 0 259  LEU A H    1 c 
ATOM   3723 H HA   . LEU A 1 244 ? 23.033  3.005   0.555   1.000 19.204 0 259  LEU A HA   1 c 
ATOM   3724 H HB2  . LEU A 1 244 ? 21.544  3.289   2.332   1.000 19.635 0 259  LEU A HB2  1 c 
ATOM   3725 H HB3  . LEU A 1 244 ? 20.559  4.139   1.409   1.000 19.635 0 259  LEU A HB3  1 c 
ATOM   3726 H HG   . LEU A 1 244 ? 20.077  2.205   0.136   1.000 19.776 0 259  LEU A HG   1 c 
ATOM   3727 H HD11 . LEU A 1 244 ? 21.983  0.919   0.399   1.000 20.078 0 259  LEU A HD11 1 c 
ATOM   3728 H HD12 . LEU A 1 244 ? 20.755  0.069   0.932   1.000 20.089 0 259  LEU A HD12 1 c 
ATOM   3729 H HD13 . LEU A 1 244 ? 21.732  0.781   1.959   1.000 20.099 0 259  LEU A HD13 1 c 
ATOM   3730 H HD21 . LEU A 1 244 ? 18.654  2.740   1.862   1.000 19.630 0 259  LEU A HD21 1 c 
ATOM   3731 H HD22 . LEU A 1 244 ? 19.538  1.919   2.892   1.000 19.630 0 259  LEU A HD22 1 c 
ATOM   3732 H HD23 . LEU A 1 244 ? 18.746  1.160   1.746   1.000 19.630 0 259  LEU A HD23 1 c 
ATOM   3733 N N    . GLN A 1 245 ? 21.178  4.898   -1.315  1.000 17.509 0 260  GLN A N    1 ? 
ATOM   3734 C CA   . GLN A 1 245 ? 20.718  5.059   -2.687  1.000 16.703 0 260  GLN A CA   1 ? 
ATOM   3735 C C    . GLN A 1 245 ? 21.892  5.065   -3.668  1.000 18.355 0 260  GLN A C    1 ? 
ATOM   3736 O O    . GLN A 1 245 ? 21.825  4.429   -4.710  1.000 16.810 0 260  GLN A O    1 ? 
ATOM   3737 C CB   . GLN A 1 245 ? 19.835  6.288   -2.805  1.000 16.875 0 260  GLN A CB   1 ? 
ATOM   3738 C CG   . GLN A 1 245 ? 19.224  6.459   -4.173  1.000 16.975 0 260  GLN A CG   1 ? 
ATOM   3739 C CD   . GLN A 1 245 ? 18.339  7.681   -4.276  1.000 19.805 0 260  GLN A CD   1 ? 
ATOM   3740 O OE1  . GLN A 1 245 ? 18.801  8.819   -4.153  1.000 20.935 0 260  GLN A OE1  1 ? 
ATOM   3741 N NE2  . GLN A 1 245 ? 17.047  7.468   -4.486  1.000 17.849 0 260  GLN A NE2  1 ? 
ATOM   3742 H H    . GLN A 1 245 ? 20.985  5.542   -0.697  1.000 17.490 0 260  GLN A H    1 c 
ATOM   3743 H HA   . GLN A 1 245 ? 20.152  4.275   -2.905  1.000 17.186 0 260  GLN A HA   1 c 
ATOM   3744 H HB2  . GLN A 1 245 ? 19.117  6.225   -2.141  1.000 16.858 0 260  GLN A HB2  1 c 
ATOM   3745 H HB3  . GLN A 1 245 ? 20.369  7.081   -2.593  1.000 16.858 0 260  GLN A HB3  1 c 
ATOM   3746 H HG2  . GLN A 1 245 ? 19.939  6.535   -4.840  1.000 17.570 0 260  GLN A HG2  1 c 
ATOM   3747 H HG3  . GLN A 1 245 ? 18.697  5.661   -4.393  1.000 17.570 0 260  GLN A HG3  1 c 
ATOM   3748 H HE21 . GLN A 1 245 ? 16.738  6.643   -4.585  1.000 18.403 0 260  GLN A HE21 1 c 
ATOM   3749 H HE22 . GLN A 1 245 ? 16.489  8.157   -4.527  1.000 18.441 0 260  GLN A HE22 1 c 
ATOM   3750 N N    . GLN A 1 246 ? 22.961  5.778   -3.304  1.000 16.720 0 261  GLN A N    1 ? 
ATOM   3751 C CA   . GLN A 1 246 ? 24.136  5.930   -4.145  1.000 16.599 0 261  GLN A CA   1 ? 
ATOM   3752 C C    . GLN A 1 246 ? 24.815  4.592   -4.345  1.000 16.849 0 261  GLN A C    1 ? 
ATOM   3753 O O    . GLN A 1 246 ? 25.086  4.184   -5.484  1.000 18.099 0 261  GLN A O    1 ? 
ATOM   3754 C CB   . GLN A 1 246 ? 24.967  7.004   -3.435  1.000 18.884 0 261  GLN A CB   1 ? 
ATOM   3755 C CG   . GLN A 1 246 ? 26.191  7.415   -4.236  1.000 20.218 0 261  GLN A CG   1 ? 
ATOM   3756 C CD   . GLN A 1 246 ? 26.800  8.662   -3.644  1.000 21.233 0 261  GLN A CD   1 ? 
ATOM   3757 O OE1  . GLN A 1 246 ? 26.498  9.037   -2.504  1.000 24.706 0 261  GLN A OE1  1 ? 
ATOM   3758 N NE2  . GLN A 1 246 ? 27.707  9.291   -4.369  1.000 21.544 0 261  GLN A NE2  1 ? 
ATOM   3759 H H    . GLN A 1 246 ? 22.953  6.193   -2.489  1.000 17.105 0 261  GLN A H    1 c 
ATOM   3760 H HA   . GLN A 1 246 ? 23.847  6.276   -5.027  1.000 17.062 0 261  GLN A HA   1 c 
ATOM   3761 H HB2  . GLN A 1 246 ? 24.404  7.791   -3.283  1.000 18.648 0 261  GLN A HB2  1 c 
ATOM   3762 H HB3  . GLN A 1 246 ? 25.252  6.663   -2.561  1.000 18.648 0 261  GLN A HB3  1 c 
ATOM   3763 H HG2  . GLN A 1 246 ? 26.852  6.691   -4.226  1.000 20.131 0 261  GLN A HG2  1 c 
ATOM   3764 H HG3  . GLN A 1 246 ? 25.936  7.585   -5.167  1.000 20.132 0 261  GLN A HG3  1 c 
ATOM   3765 H HE21 . GLN A 1 246 ? 27.947  8.964   -5.157  1.000 21.453 0 261  GLN A HE21 1 c 
ATOM   3766 H HE22 . GLN A 1 246 ? 28.074  10.039  -4.066  1.000 21.471 0 261  GLN A HE22 1 c 
ATOM   3767 N N    . LYS A 1 247 ? 25.022  3.836   -3.245  1.000 16.980 0 262  LYS A N    1 ? 
ATOM   3768 C CA   . LYS A 1 247 ? 25.663  2.527   -3.366  1.000 18.143 0 262  LYS A CA   1 ? 
ATOM   3769 C C    . LYS A 1 247 ? 24.825  1.542   -4.171  1.000 15.192 0 262  LYS A C    1 ? 
ATOM   3770 O O    . LYS A 1 247 ? 25.341  0.748   -4.959  1.000 18.104 0 262  LYS A O    1 ? 
ATOM   3771 C CB   . LYS A 1 247 ? 26.019  1.919   -2.006  1.000 19.404 0 262  LYS A CB   1 ? 
ATOM   3772 C CG   . LYS A 1 247 ? 27.228  2.627   -1.408  1.000 20.822 0 262  LYS A CG   1 ? 
ATOM   3773 C CD   . LYS A 1 247 ? 27.536  2.066   -0.019  1.000 22.770 0 262  LYS A CD   1 ? 
ATOM   3774 C CE   . LYS A 1 247 ? 28.890  2.522   0.428   1.000 25.383 0 262  LYS A CE   1 ? 
ATOM   3775 N NZ   . LYS A 1 247 ? 29.145  2.088   1.813   1.000 29.100 0 262  LYS A NZ   1 ? 
ATOM   3776 H H    . LYS A 1 247 ? 24.768  4.137   -2.420  1.000 17.207 0 262  LYS A H    1 c 
ATOM   3777 H HA   . LYS A 1 247 ? 26.516  2.659   -3.853  1.000 17.583 0 262  LYS A HA   1 c 
ATOM   3778 H HB2  . LYS A 1 247 ? 25.258  2.007   -1.393  1.000 19.417 0 262  LYS A HB2  1 c 
ATOM   3779 H HB3  . LYS A 1 247 ? 26.224  0.965   -2.111  1.000 19.396 0 262  LYS A HB3  1 c 
ATOM   3780 H HG2  . LYS A 1 247 ? 28.003  2.495   -1.997  1.000 20.906 0 262  LYS A HG2  1 c 
ATOM   3781 H HG3  . LYS A 1 247 ? 27.040  3.588   -1.342  1.000 20.907 0 262  LYS A HG3  1 c 
ATOM   3782 H HD2  . LYS A 1 247 ? 26.859  2.378   0.620   1.000 22.915 0 262  LYS A HD2  1 c 
ATOM   3783 H HD3  . LYS A 1 247 ? 27.515  1.085   -0.048  1.000 22.891 0 262  LYS A HD3  1 c 
ATOM   3784 H HE2  . LYS A 1 247 ? 29.574  2.148   -0.157  1.000 25.569 0 262  LYS A HE2  1 c 
ATOM   3785 H HE3  . LYS A 1 247 ? 28.943  3.493   0.381   1.000 25.569 0 262  LYS A HE3  1 c 
ATOM   3786 H HZ1  . LYS A 1 247 ? 29.143  1.184   1.854   1.000 27.895 0 262  LYS A HZ1  1 c 
ATOM   3787 H HZ2  . LYS A 1 247 ? 28.501  2.413   2.360   1.000 27.835 0 262  LYS A HZ2  1 c 
ATOM   3788 H HZ3  . LYS A 1 247 ? 29.952  2.396   2.086   1.000 27.887 0 262  LYS A HZ3  1 c 
ATOM   3789 N N    . LEU A 1 248 ? 23.516  1.552   -3.980  1.000 17.422 0 263  LEU A N    1 ? 
ATOM   3790 C CA   . LEU A 1 248 ? 22.638  0.677   -4.736  1.000 17.706 0 263  LEU A CA   1 ? 
ATOM   3791 C C    . LEU A 1 248 ? 22.612  1.054   -6.216  1.000 16.638 0 263  LEU A C    1 ? 
ATOM   3792 O O    . LEU A 1 248 ? 22.594  0.155   -7.069  1.000 16.817 0 263  LEU A O    1 ? 
ATOM   3793 C CB   . LEU A 1 248 ? 21.243  0.659   -4.109  1.000 16.341 0 263  LEU A CB   1 ? 
ATOM   3794 C CG   . LEU A 1 248 ? 21.102  -0.068  -2.764  1.000 16.667 0 263  LEU A CG   1 ? 
ATOM   3795 C CD1  . LEU A 1 248 ? 19.682  0.169   -2.279  1.000 16.520 0 263  LEU A CD1  1 ? 
ATOM   3796 C CD2  . LEU A 1 248 ? 21.417  -1.536  -2.837  1.000 18.195 0 263  LEU A CD2  1 ? 
ATOM   3797 H H    . LEU A 1 248 ? 23.153  2.114   -3.357  1.000 16.926 0 263  LEU A H    1 c 
ATOM   3798 H HA   . LEU A 1 248 ? 23.013  -0.238  -4.677  1.000 17.194 0 263  LEU A HA   1 c 
ATOM   3799 H HB2  . LEU A 1 248 ? 20.951  1.592   -3.989  1.000 16.717 0 263  LEU A HB2  1 c 
ATOM   3800 H HB3  . LEU A 1 248 ? 20.625  0.242   -4.752  1.000 16.717 0 263  LEU A HB3  1 c 
ATOM   3801 H HG   . LEU A 1 248 ? 21.725  0.350   -2.116  1.000 16.858 0 263  LEU A HG   1 c 
ATOM   3802 H HD11 . LEU A 1 248 ? 19.520  1.124   -2.200  1.000 16.562 0 263  LEU A HD11 1 c 
ATOM   3803 H HD12 . LEU A 1 248 ? 19.561  -0.252  -1.411  1.000 16.562 0 263  LEU A HD12 1 c 
ATOM   3804 H HD13 . LEU A 1 248 ? 19.054  -0.214  -2.913  1.000 16.557 0 263  LEU A HD13 1 c 
ATOM   3805 H HD21 . LEU A 1 248 ? 22.364  -1.658  -3.014  1.000 17.721 0 263  LEU A HD21 1 c 
ATOM   3806 H HD22 . LEU A 1 248 ? 20.899  -1.944  -3.552  1.000 17.723 0 263  LEU A HD22 1 c 
ATOM   3807 H HD23 . LEU A 1 248 ? 21.189  -1.959  -1.992  1.000 17.724 0 263  LEU A HD23 1 c 
ATOM   3808 N N    . LEU A 1 249 ? 22.582  2.351   -6.523  1.000 15.722 0 264  LEU A N    1 ? 
ATOM   3809 C CA   . LEU A 1 249 ? 22.679  2.778   -7.919  1.000 17.138 0 264  LEU A CA   1 ? 
ATOM   3810 C C    . LEU A 1 249 ? 24.006  2.345   -8.567  1.000 16.137 0 264  LEU A C    1 ? 
ATOM   3811 O O    . LEU A 1 249 ? 23.965  1.886   -9.719  1.000 16.606 0 264  LEU A O    1 ? 
ATOM   3812 C CB   . LEU A 1 249 ? 22.405  4.264   -8.084  1.000 15.831 0 264  LEU A CB   1 ? 
ATOM   3813 C CG   . LEU A 1 249 ? 20.919  4.652   -7.932  1.000 17.570 0 264  LEU A CG   1 ? 
ATOM   3814 C CD1  . LEU A 1 249 ? 20.778  6.129   -7.905  1.000 17.908 0 264  LEU A CD1  1 ? 
ATOM   3815 C CD2  . LEU A 1 249 ? 20.071  4.036   -9.028  1.000 17.649 0 264  LEU A CD2  1 ? 
ATOM   3816 H H    . LEU A 1 249 ? 22.496  2.981   -5.866  1.000 16.261 0 264  LEU A H    1 c 
ATOM   3817 H HA   . LEU A 1 249 ? 21.970  2.290   -8.407  1.000 16.443 0 264  LEU A HA   1 c 
ATOM   3818 H HB2  . LEU A 1 249 ? 22.929  4.754   -7.409  1.000 16.502 0 264  LEU A HB2  1 c 
ATOM   3819 H HB3  . LEU A 1 249 ? 22.711  4.540   -8.979  1.000 16.501 0 264  LEU A HB3  1 c 
ATOM   3820 H HG   . LEU A 1 249 ? 20.597  4.299   -7.063  1.000 17.315 0 264  LEU A HG   1 c 
ATOM   3821 H HD11 . LEU A 1 249 ? 21.285  6.490   -7.158  1.000 17.805 0 264  LEU A HD11 1 c 
ATOM   3822 H HD12 . LEU A 1 249 ? 19.840  6.364   -7.802  1.000 17.804 0 264  LEU A HD12 1 c 
ATOM   3823 H HD13 . LEU A 1 249 ? 21.116  6.503   -8.736  1.000 17.805 0 264  LEU A HD13 1 c 
ATOM   3824 H HD21 . LEU A 1 249 ? 19.973  3.082   -8.868  1.000 17.614 0 264  LEU A HD21 1 c 
ATOM   3825 H HD22 . LEU A 1 249 ? 20.500  4.177   -9.889  1.000 17.624 0 264  LEU A HD22 1 c 
ATOM   3826 H HD23 . LEU A 1 249 ? 19.193  4.453   -9.033  1.000 17.626 0 264  LEU A HD23 1 c 
ATOM   3827 N N    . TRP A 1 250 ? 25.139  2.392   -7.817  1.000 17.474 0 265  TRP A N    1 ? 
ATOM   3828 C CA   . TRP A 1 250 ? 26.394  1.912   -8.403  1.000 19.111 0 265  TRP A CA   1 ? 
ATOM   3829 C C    . TRP A 1 250 ? 26.385  0.408   -8.662  1.000 18.718 0 265  TRP A C    1 ? 
ATOM   3830 O O    . TRP A 1 250 ? 26.944  -0.090  -9.650  1.000 18.353 0 265  TRP A O    1 ? 
ATOM   3831 C CB   . TRP A 1 250 ? 27.605  2.308   -7.558  1.000 19.257 0 265  TRP A CB   1 ? 
ATOM   3832 C CG   . TRP A 1 250 ? 28.077  3.713   -7.821  1.000 17.357 0 265  TRP A CG   1 ? 
ATOM   3833 C CD1  . TRP A 1 250 ? 28.106  4.725   -6.926  1.000 20.022 0 265  TRP A CD1  1 ? 
ATOM   3834 C CD2  . TRP A 1 250 ? 28.427  4.291   -9.124  1.000 16.891 0 265  TRP A CD2  1 ? 
ATOM   3835 N NE1  . TRP A 1 250 ? 28.527  5.881   -7.537  1.000 20.615 0 265  TRP A NE1  1 ? 
ATOM   3836 C CE2  . TRP A 1 250 ? 28.759  5.633   -8.854  1.000 17.828 0 265  TRP A CE2  1 ? 
ATOM   3837 C CE3  . TRP A 1 250 ? 28.583  3.782   -10.420 1.000 18.719 0 265  TRP A CE3  1 ? 
ATOM   3838 C CZ2  . TRP A 1 250 ? 29.134  6.519   -9.872  1.000 18.670 0 265  TRP A CZ2  1 ? 
ATOM   3839 C CZ3  . TRP A 1 250 ? 28.995  4.650   -11.417 1.000 19.331 0 265  TRP A CZ3  1 ? 
ATOM   3840 C CH2  . TRP A 1 250 ? 29.257  5.991   -11.130 1.000 18.638 0 265  TRP A CH2  1 ? 
ATOM   3841 H H    . TRP A 1 250 ? 25.129  2.719   -6.964  1.000 17.497 0 265  TRP A H    1 c 
ATOM   3842 H HA   . TRP A 1 250 ? 26.492  2.360   -9.284  1.000 18.691 0 265  TRP A HA   1 c 
ATOM   3843 H HB2  . TRP A 1 250 ? 27.369  2.222   -6.610  1.000 18.765 0 265  TRP A HB2  1 c 
ATOM   3844 H HB3  . TRP A 1 250 ? 28.339  1.685   -7.749  1.000 18.792 0 265  TRP A HB3  1 c 
ATOM   3845 H HD1  . TRP A 1 250 ? 27.913  4.648   -6.005  1.000 19.500 0 265  TRP A HD1  1 c 
ATOM   3846 H HE1  . TRP A 1 250 ? 28.645  6.648   -7.138  1.000 19.763 0 265  TRP A HE1  1 c 
ATOM   3847 H HE3  . TRP A 1 250 ? 28.400  2.877   -10.608 1.000 18.427 0 265  TRP A HE3  1 c 
ATOM   3848 H HZ2  . TRP A 1 250 ? 29.327  7.423   -9.693  1.000 18.493 0 265  TRP A HZ2  1 c 
ATOM   3849 H HZ3  . TRP A 1 250 ? 29.082  4.337   -12.302 1.000 19.003 0 265  TRP A HZ3  1 c 
ATOM   3850 H HH2  . TRP A 1 250 ? 29.528  6.558   -11.830 1.000 18.837 0 265  TRP A HH2  1 c 
ATOM   3851 N N    . LEU A 1 251 ? 25.756  -0.349  -7.746  1.000 18.541 0 266  LEU A N    1 ? 
ATOM   3852 C CA   . LEU A 1 251 ? 25.584  -1.780  -7.913  1.000 19.192 0 266  LEU A CA   1 ? 
ATOM   3853 C C    . LEU A 1 251 ? 24.823  -2.082  -9.189  1.000 18.016 0 266  LEU A C    1 ? 
ATOM   3854 O O    . LEU A 1 251 ? 25.266  -2.878  -10.015 1.000 18.332 0 266  LEU A O    1 ? 
ATOM   3855 C CB   . LEU A 1 251 ? 24.929  -2.404  -6.678  1.000 18.791 0 266  LEU A CB   1 ? 
ATOM   3856 C CG   . LEU A 1 251 ? 24.491  -3.862  -6.801  1.000 20.041 0 266  LEU A CG   1 ? 
ATOM   3857 C CD1  . LEU A 1 251 ? 25.668  -4.821  -6.937  1.000 22.784 0 266  LEU A CD1  1 ? 
ATOM   3858 C CD2  . LEU A 1 251 ? 23.613  -4.273  -5.614  1.000 20.082 0 266  LEU A CD2  1 ? 
ATOM   3859 H H    . LEU A 1 251 ? 25.432  0.045   -6.988  1.000 18.726 0 266  LEU A H    1 c 
ATOM   3860 H HA   . LEU A 1 251 ? 26.489  -2.173  -8.013  1.000 18.763 0 266  LEU A HA   1 c 
ATOM   3861 H HB2  . LEU A 1 251 ? 25.563  -2.334  -5.928  1.000 19.158 0 266  LEU A HB2  1 c 
ATOM   3862 H HB3  . LEU A 1 251 ? 24.140  -1.863  -6.444  1.000 19.145 0 266  LEU A HB3  1 c 
ATOM   3863 H HG   . LEU A 1 251 ? 23.939  -3.948  -7.620  1.000 20.279 0 266  LEU A HG   1 c 
ATOM   3864 H HD11 . LEU A 1 251 ? 26.177  -4.601  -7.735  1.000 21.925 0 266  LEU A HD11 1 c 
ATOM   3865 H HD12 . LEU A 1 251 ? 25.338  -5.733  -7.005  1.000 21.935 0 266  LEU A HD12 1 c 
ATOM   3866 H HD13 . LEU A 1 251 ? 26.242  -4.744  -6.156  1.000 21.935 0 266  LEU A HD13 1 c 
ATOM   3867 H HD21 . LEU A 1 251 ? 22.820  -3.712  -5.587  1.000 20.070 0 266  LEU A HD21 1 c 
ATOM   3868 H HD22 . LEU A 1 251 ? 24.113  -4.167  -4.788  1.000 20.070 0 266  LEU A HD22 1 c 
ATOM   3869 H HD23 . LEU A 1 251 ? 23.347  -5.203  -5.713  1.000 20.070 0 266  LEU A HD23 1 c 
ATOM   3870 N N    . LEU A 1 252 ? 23.676  -1.387  -9.378  1.000 16.170 0 267  LEU A N    1 ? 
ATOM   3871 C CA   . LEU A 1 252 ? 22.889  -1.582  -10.571 1.000 16.205 0 267  LEU A CA   1 ? 
ATOM   3872 C C    . LEU A 1 252 ? 23.670  -1.170  -11.809 1.000 14.630 0 267  LEU A C    1 ? 
ATOM   3873 O O    . LEU A 1 252 ? 23.555  -1.830  -12.847 1.000 18.304 0 267  LEU A O    1 ? 
ATOM   3874 C CB   . LEU A 1 252 ? 21.586  -0.818  -10.406 1.000 15.040 0 267  LEU A CB   1 ? 
ATOM   3875 C CG   . LEU A 1 252 ? 20.568  -1.416  -9.436  1.000 17.052 0 267  LEU A CG   1 ? 
ATOM   3876 C CD1  . LEU A 1 252 ? 19.695  -0.292  -8.941  1.000 17.421 0 267  LEU A CD1  1 ? 
ATOM   3877 C CD2  . LEU A 1 252 ? 19.739  -2.525  -10.043 1.000 17.636 0 267  LEU A CD2  1 ? 
ATOM   3878 H H    . LEU A 1 252 ? 23.391  -0.793  -8.744  1.000 16.609 0 267  LEU A H    1 c 
ATOM   3879 H HA   . LEU A 1 252 ? 22.683  -2.548  -10.646 1.000 15.703 0 267  LEU A HA   1 c 
ATOM   3880 H HB2  . LEU A 1 252 ? 21.802  0.096   -10.109 1.000 15.770 0 267  LEU A HB2  1 c 
ATOM   3881 H HB3  . LEU A 1 252 ? 21.161  -0.743  -11.292 1.000 15.751 0 267  LEU A HB3  1 c 
ATOM   3882 H HG   . LEU A 1 252 ? 21.061  -1.789  -8.660  1.000 16.831 0 267  LEU A HG   1 c 
ATOM   3883 H HD11 . LEU A 1 252 ? 20.220  0.306   -8.383  1.000 17.290 0 267  LEU A HD11 1 c 
ATOM   3884 H HD12 . LEU A 1 252 ? 18.960  -0.657  -8.419  1.000 17.302 0 267  LEU A HD12 1 c 
ATOM   3885 H HD13 . LEU A 1 252 ? 19.340  0.201   -9.699  1.000 17.280 0 267  LEU A HD13 1 c 
ATOM   3886 H HD21 . LEU A 1 252 ? 20.323  -3.246  -10.334 1.000 17.461 0 267  LEU A HD21 1 c 
ATOM   3887 H HD22 . LEU A 1 252 ? 19.245  -2.182  -10.806 1.000 17.461 0 267  LEU A HD22 1 c 
ATOM   3888 H HD23 . LEU A 1 252 ? 19.114  -2.864  -9.380  1.000 17.461 0 267  LEU A HD23 1 c 
ATOM   3889 N N    . TYR A 1 253 ? 24.402  -0.091  -11.725 1.000 16.714 0 268  TYR A N    1 ? 
ATOM   3890 C CA   . TYR A 1 253 ? 25.181  0.383   -12.861 1.000 17.802 0 268  TYR A CA   1 ? 
ATOM   3891 C C    . TYR A 1 253 ? 26.190  -0.666  -13.331 1.000 18.403 0 268  TYR A C    1 ? 
ATOM   3892 O O    . TYR A 1 253 ? 26.256  -0.960  -14.528 1.000 19.522 0 268  TYR A O    1 ? 
ATOM   3893 C CB   . TYR A 1 253 ? 25.956  1.615   -12.429 1.000 17.037 0 268  TYR A CB   1 ? 
ATOM   3894 C CG   . TYR A 1 253 ? 26.870  2.266   -13.461 1.000 18.142 0 268  TYR A CG   1 ? 
ATOM   3895 C CD1  . TYR A 1 253 ? 28.172  1.823   -13.652 1.000 19.811 0 268  TYR A CD1  1 ? 
ATOM   3896 C CD2  . TYR A 1 253 ? 26.504  3.427   -14.099 1.000 22.828 0 268  TYR A CD2  1 ? 
ATOM   3897 C CE1  . TYR A 1 253 ? 29.049  2.448   -14.525 1.000 23.734 0 268  TYR A CE1  1 ? 
ATOM   3898 C CE2  . TYR A 1 253 ? 27.369  4.075   -14.969 1.000 24.173 0 268  TYR A CE2  1 ? 
ATOM   3899 C CZ   . TYR A 1 253 ? 28.640  3.579   -15.190 1.000 25.145 0 268  TYR A CZ   1 ? 
ATOM   3900 O OH   . TYR A 1 253 ? 29.479  4.250   -16.039 1.000 27.613 0 268  TYR A OH   1 ? 
ATOM   3901 H H    . TYR A 1 253 ? 24.425  0.384   -10.944 1.000 16.422 0 268  TYR A H    1 c 
ATOM   3902 H HA   . TYR A 1 253 ? 24.570  0.618   -13.608 1.000 17.550 0 268  TYR A HA   1 c 
ATOM   3903 H HB2  . TYR A 1 253 ? 25.307  2.287   -12.124 1.000 17.515 0 268  TYR A HB2  1 c 
ATOM   3904 H HB3  . TYR A 1 253 ? 26.499  1.372   -11.648 1.000 17.496 0 268  TYR A HB3  1 c 
ATOM   3905 H HD1  . TYR A 1 253 ? 28.459  1.046   -13.201 1.000 20.321 0 268  TYR A HD1  1 c 
ATOM   3906 H HD2  . TYR A 1 253 ? 25.639  3.778   -13.961 1.000 21.880 0 268  TYR A HD2  1 c 
ATOM   3907 H HE1  . TYR A 1 253 ? 29.916  2.104   -14.659 1.000 23.042 0 268  TYR A HE1  1 c 
ATOM   3908 H HE2  . TYR A 1 253 ? 27.085  4.850   -15.423 1.000 24.006 0 268  TYR A HE2  1 c 
ATOM   3909 H HH   . TYR A 1 253 ? 29.407  3.938   -16.834 0.000 27.600 0 268  TYR A HH   1 c 
ATOM   3910 N N    . ASP A 1 254 ? 26.917  -1.218  -12.348 1.000 19.499 0 269  ASP A N    1 ? 
ATOM   3911 C CA   . ASP A 1 254 ? 27.995  -2.162  -12.604 1.000 21.807 0 269  ASP A CA   1 ? 
ATOM   3912 C C    . ASP A 1 254 ? 27.440  -3.433  -13.221 1.000 22.435 0 269  ASP A C    1 ? 
ATOM   3913 O O    . ASP A 1 254 ? 28.099  -4.088  -14.022 1.000 22.258 0 269  ASP A O    1 ? 
ATOM   3914 C CB   . ASP A 1 254 ? 28.760  -2.466  -11.323 1.000 22.897 0 269  ASP A CB   1 ? 
ATOM   3915 C CG   . ASP A 1 254 ? 29.705  -1.380  -10.871 1.000 25.209 0 269  ASP A CG   1 ? 
ATOM   3916 O OD1  . ASP A 1 254 ? 29.972  -0.433  -11.689 1.000 23.671 0 269  ASP A OD1  1 ? 
ATOM   3917 O OD2  . ASP A 1 254 ? 30.124  -1.466  -9.693  1.000 27.096 0 269  ASP A OD2  1 ? 
ATOM   3918 H H    . ASP A 1 254 ? 26.733  -0.992  -11.481 1.000 19.701 0 269  ASP A H    1 c 
ATOM   3919 H HA   . ASP A 1 254 ? 28.616  -1.752  -13.247 1.000 21.671 0 269  ASP A HA   1 c 
ATOM   3920 H HB2  . ASP A 1 254 ? 28.118  -2.634  -10.601 1.000 23.129 0 269  ASP A HB2  1 c 
ATOM   3921 H HB3  . ASP A 1 254 ? 29.283  -3.284  -11.455 1.000 23.147 0 269  ASP A HB3  1 c 
ATOM   3922 N N    . LEU A 1 255 ? 26.210  -3.797  -12.857 1.000 19.080 0 270  LEU A N    1 ? 
ATOM   3923 C CA   . LEU A 1 255 ? 25.591  -5.003  -13.373 1.000 21.999 0 270  LEU A CA   1 ? 
ATOM   3924 C C    . LEU A 1 255 ? 24.872  -4.810  -14.706 1.000 21.303 0 270  LEU A C    1 ? 
ATOM   3925 O O    . LEU A 1 255 ? 24.347  -5.782  -15.284 1.000 22.497 0 270  LEU A O    1 ? 
ATOM   3926 C CB   . LEU A 1 255 ? 24.629  -5.510  -12.314 1.000 21.025 0 270  LEU A CB   1 ? 
ATOM   3927 C CG   . LEU A 1 255 ? 25.244  -6.082  -11.041 1.000 23.872 0 270  LEU A CG   1 ? 
ATOM   3928 C CD1  . LEU A 1 255 ? 24.056  -6.405  -10.131 1.000 25.095 0 270  LEU A CD1  1 ? 
ATOM   3929 C CD2  . LEU A 1 255 ? 26.068  -7.306  -11.383 1.000 26.883 0 270  LEU A CD2  1 ? 
ATOM   3930 H H    . LEU A 1 255 ? 25.744  -3.284  -12.262 1.000 20.484 0 270  LEU A H    1 c 
ATOM   3931 H HA   . LEU A 1 255 ? 26.302  -5.678  -13.509 1.000 21.165 0 270  LEU A HA   1 c 
ATOM   3932 H HB2  . LEU A 1 255 ? 24.032  -4.768  -12.063 1.000 21.904 0 270  LEU A HB2  1 c 
ATOM   3933 H HB3  . LEU A 1 255 ? 24.065  -6.207  -12.722 1.000 21.930 0 270  LEU A HB3  1 c 
ATOM   3934 H HG   . LEU A 1 255 ? 25.819  -5.395  -10.615 1.000 24.021 0 270  LEU A HG   1 c 
ATOM   3935 H HD11 . LEU A 1 255 ? 23.570  -5.588  -9.928  1.000 24.699 0 270  LEU A HD11 1 c 
ATOM   3936 H HD12 . LEU A 1 255 ? 24.379  -6.801  -9.304  1.000 24.715 0 270  LEU A HD12 1 c 
ATOM   3937 H HD13 . LEU A 1 255 ? 23.463  -7.031  -10.579 1.000 24.682 0 270  LEU A HD13 1 c 
ATOM   3938 H HD21 . LEU A 1 255 ? 26.884  -7.035  -11.837 1.000 25.877 0 270  LEU A HD21 1 c 
ATOM   3939 H HD22 . LEU A 1 255 ? 25.555  -7.893  -11.964 1.000 25.877 0 270  LEU A HD22 1 c 
ATOM   3940 H HD23 . LEU A 1 255 ? 26.298  -7.781  -10.566 1.000 25.924 0 270  LEU A HD23 1 c 
ATOM   3941 N N    . GLY A 1 256 ? 24.824  -3.557  -15.197 1.000 20.421 0 271  GLY A N    1 ? 
ATOM   3942 C CA   . GLY A 1 256 ? 24.247  -3.228  -16.483 1.000 18.978 0 271  GLY A CA   1 ? 
ATOM   3943 C C    . GLY A 1 256 ? 22.767  -2.810  -16.434 1.000 19.675 0 271  GLY A C    1 ? 
ATOM   3944 O O    . GLY A 1 256 ? 22.166  -2.616  -17.489 1.000 20.550 0 271  GLY A O    1 ? 
ATOM   3945 H H    . GLY A 1 256 ? 25.161  -2.875  -14.692 1.000 20.287 0 271  GLY A H    1 c 
ATOM   3946 H HA2  . GLY A 1 256 ? 24.770  -2.493  -16.876 1.000 19.719 0 271  GLY A HA2  1 c 
ATOM   3947 H HA3  . GLY A 1 256 ? 24.341  -4.007  -17.080 1.000 19.542 0 271  GLY A HA3  1 c 
ATOM   3948 N N    . HIS A 1 257 ? 22.194  -2.651  -15.238 1.000 18.154 0 272  HIS A N    1 ? 
ATOM   3949 C CA   . HIS A 1 257 ? 20.748  -2.544  -15.128 1.000 17.963 0 272  HIS A CA   1 ? 
ATOM   3950 C C    . HIS A 1 257 ? 20.278  -1.091  -15.172 1.000 18.481 0 272  HIS A C    1 ? 
ATOM   3951 O O    . HIS A 1 257 ? 19.064  -0.876  -15.100 1.000 18.279 0 272  HIS A O    1 ? 
ATOM   3952 C CB   . HIS A 1 257 ? 20.228  -3.247  -13.876 1.000 19.487 0 272  HIS A CB   1 ? 
ATOM   3953 C CG   . HIS A 1 257 ? 20.599  -4.691  -13.832 1.000 20.589 0 272  HIS A CG   1 ? 
ATOM   3954 N ND1  . HIS A 1 257 ? 20.483  -5.515  -14.935 1.000 25.004 0 272  HIS A ND1  1 ? 
ATOM   3955 C CD2  . HIS A 1 257 ? 21.156  -5.438  -12.855 1.000 22.905 0 272  HIS A CD2  1 ? 
ATOM   3956 C CE1  . HIS A 1 257 ? 20.920  -6.726  -14.608 1.000 24.428 0 272  HIS A CE1  1 ? 
ATOM   3957 N NE2  . HIS A 1 257 ? 21.312  -6.714  -13.356 1.000 20.823 0 272  HIS A NE2  1 ? 
ATOM   3958 H H    . HIS A 1 257 ? 22.705  -2.601  -14.482 1.000 18.476 0 272  HIS A H    1 c 
ATOM   3959 H HA   . HIS A 1 257 ? 20.357  -3.010  -15.908 1.000 18.416 0 272  HIS A HA   1 c 
ATOM   3960 H HB2  . HIS A 1 257 ? 20.596  -2.797  -13.084 1.000 19.377 0 272  HIS A HB2  1 c 
ATOM   3961 H HB3  . HIS A 1 257 ? 19.250  -3.166  -13.849 1.000 19.372 0 272  HIS A HB3  1 c 
ATOM   3962 H HD1  . HIS A 1 257 ? 20.190  -5.263  -15.729 0.000 25.060 0 272  HIS A HD1  1 c 
ATOM   3963 H HD2  . HIS A 1 257 ? 21.355  -5.163  -11.982 1.000 21.892 0 272  HIS A HD2  1 c 
ATOM   3964 H HE1  . HIS A 1 257 ? 20.926  -7.474  -15.180 1.000 23.624 0 272  HIS A HE1  1 c 
ATOM   3965 H HE2  . HIS A 1 257 ? 21.638  -7.398  -12.920 0.000 20.880 0 272  HIS A HE2  1 c 
ATOM   3966 N N    . LEU A 1 258 ? 21.184  -0.126  -15.336 1.000 17.495 0 273  LEU A N    1 ? 
ATOM   3967 C CA   . LEU A 1 258 ? 20.789  1.260   -15.627 1.000 16.860 0 273  LEU A CA   1 ? 
ATOM   3968 C C    . LEU A 1 258 ? 20.914  1.591   -17.123 1.000 17.458 0 273  LEU A C    1 ? 
ATOM   3969 O O    . LEU A 1 258 ? 20.639  2.726   -17.516 1.000 17.173 0 273  LEU A O    1 ? 
ATOM   3970 C CB   . LEU A 1 258 ? 21.568  2.268   -14.798 1.000 15.469 0 273  LEU A CB   1 ? 
ATOM   3971 C CG   . LEU A 1 258 ? 21.531  2.055   -13.285 1.000 15.269 0 273  LEU A CG   1 ? 
ATOM   3972 C CD1  . LEU A 1 258 ? 22.230  3.179   -12.579 1.000 16.423 0 273  LEU A CD1  1 ? 
ATOM   3973 C CD2  . LEU A 1 258 ? 20.129  1.829   -12.737 1.000 15.789 0 273  LEU A CD2  1 ? 
ATOM   3974 H H    . LEU A 1 258 ? 22.073  -0.320  -15.256 1.000 17.597 0 273  LEU A H    1 c 
ATOM   3975 H HA   . LEU A 1 258 ? 19.831  1.349   -15.394 1.000 16.826 0 273  LEU A HA   1 c 
ATOM   3976 H HB2  . LEU A 1 258 ? 22.508  2.246   -15.091 1.000 15.732 0 273  LEU A HB2  1 c 
ATOM   3977 H HB3  . LEU A 1 258 ? 21.215  3.166   -14.993 1.000 15.738 0 273  LEU A HB3  1 c 
ATOM   3978 H HG   . LEU A 1 258 ? 22.048  1.231   -13.092 1.000 15.617 0 273  LEU A HG   1 c 
ATOM   3979 H HD11 . LEU A 1 258 ? 23.155  3.223   -12.874 1.000 16.069 0 273  LEU A HD11 1 c 
ATOM   3980 H HD12 . LEU A 1 258 ? 22.203  3.027   -11.619 1.000 16.066 0 273  LEU A HD12 1 c 
ATOM   3981 H HD13 . LEU A 1 258 ? 21.785  4.019   -12.785 1.000 16.069 0 273  LEU A HD13 1 c 
ATOM   3982 H HD21 . LEU A 1 258 ? 19.797  0.965   -13.037 1.000 15.648 0 273  LEU A HD21 1 c 
ATOM   3983 H HD22 . LEU A 1 258 ? 19.537  2.531   -13.057 1.000 15.635 0 273  LEU A HD22 1 c 
ATOM   3984 H HD23 . LEU A 1 258 ? 20.153  1.845   -11.766 1.000 15.639 0 273  LEU A HD23 1 c 
ATOM   3985 N N    . GLU A 1 259 ? 21.292  0.610   -17.964 1.000 17.116 0 274  GLU A N    1 ? 
ATOM   3986 C CA   . GLU A 1 259 ? 21.499  0.836   -19.392 1.000 17.799 0 274  GLU A CA   1 ? 
ATOM   3987 C C    . GLU A 1 259 ? 20.307  1.508   -20.055 1.000 16.089 0 274  GLU A C    1 ? 
ATOM   3988 O O    . GLU A 1 259 ? 20.514  2.371   -20.895 1.000 16.992 0 274  GLU A O    1 ? 
ATOM   3989 C CB   . GLU A 1 259 ? 21.775  -0.526  -20.025 1.000 19.903 0 274  GLU A CB   1 ? 
ATOM   3990 C CG   . GLU A 1 259 ? 21.939  -0.528  -21.535 1.000 23.700 0 274  GLU A CG   1 ? 
ATOM   3991 C CD   . GLU A 1 259 ? 23.260  0.037   -22.030 1.000 31.284 0 274  GLU A CD   1 ? 
ATOM   3992 O OE1  . GLU A 1 259 ? 24.178  0.350   -21.197 1.000 28.840 0 274  GLU A OE1  1 ? 
ATOM   3993 O OE2  . GLU A 1 259 ? 23.336  0.167   -23.303 1.000 27.932 0 274  GLU A OE2  1 ? 
ATOM   3994 H H    . GLU A 1 259 ? 21.426  -0.231  -17.633 1.000 17.409 0 274  GLU A H    1 c 
ATOM   3995 H HA   . GLU A 1 259 ? 22.295  1.415   -19.504 1.000 17.691 0 274  GLU A HA   1 c 
ATOM   3996 H HB2  . GLU A 1 259 ? 22.585  -0.900  -19.622 1.000 20.281 0 274  GLU A HB2  1 c 
ATOM   3997 H HB3  . GLU A 1 259 ? 21.033  -1.126  -19.804 1.000 20.199 0 274  GLU A HB3  1 c 
ATOM   3998 H HG2  . GLU A 1 259 ? 21.857  -1.450  -21.860 1.000 24.250 0 274  GLU A HG2  1 c 
ATOM   3999 H HG3  . GLU A 1 259 ? 21.211  -0.012  -21.938 1.000 24.127 0 274  GLU A HG3  1 c 
ATOM   4000 N N    A ARG A 1 260 ? 19.082  1.085   -19.686 0.500 15.717 0 275  ARG A N    1 ? 
ATOM   4001 N N    B ARG A 1 260 ? 19.082  1.088   -19.688 0.500 16.183 0 275  ARG A N    1 ? 
ATOM   4002 C CA   A ARG A 1 260 ? 17.858  1.575   -20.298 0.500 16.586 0 275  ARG A CA   1 ? 
ATOM   4003 C CA   B ARG A 1 260 ? 17.864  1.589   -20.301 0.500 17.447 0 275  ARG A CA   1 ? 
ATOM   4004 C C    A ARG A 1 260 ? 17.059  2.479   -19.347 0.500 15.233 0 275  ARG A C    1 ? 
ATOM   4005 C C    B ARG A 1 260 ? 17.055  2.466   -19.335 0.500 15.650 0 275  ARG A C    1 ? 
ATOM   4006 O O    A ARG A 1 260 ? 15.843  2.578   -19.510 0.500 15.469 0 275  ARG A O    1 ? 
ATOM   4007 O O    B ARG A 1 260 ? 15.833  2.526   -19.473 0.500 15.785 0 275  ARG A O    1 ? 
ATOM   4008 C CB   A ARG A 1 260 ? 16.986  0.380   -20.716 0.500 17.124 0 275  ARG A CB   1 ? 
ATOM   4009 C CB   B ARG A 1 260 ? 17.010  0.394   -20.751 0.500 18.717 0 275  ARG A CB   1 ? 
ATOM   4010 C CG   A ARG A 1 260 ? 17.691  -0.642  -21.599 0.500 17.388 0 275  ARG A CG   1 ? 
ATOM   4011 C CG   B ARG A 1 260 ? 17.786  -0.580  -21.626 0.500 19.709 0 275  ARG A CG   1 ? 
ATOM   4012 C CD   A ARG A 1 260 ? 16.793  -1.780  -22.103 0.500 21.224 0 275  ARG A CD   1 ? 
ATOM   4013 C CD   B ARG A 1 260 ? 16.964  -1.734  -22.184 0.500 24.612 0 275  ARG A CD   1 ? 
ATOM   4014 N NE   A ARG A 1 260 ? 17.511  -2.691  -23.006 0.500 22.263 0 275  ARG A NE   1 ? 
ATOM   4015 N NE   B ARG A 1 260 ? 16.495  -2.662  -21.150 0.500 27.069 0 275  ARG A NE   1 ? 
ATOM   4016 C CZ   A ARG A 1 260 ? 17.157  -3.090  -24.234 0.500 26.980 0 275  ARG A CZ   1 ? 
ATOM   4017 C CZ   B ARG A 1 260 ? 15.879  -3.822  -21.379 0.500 29.642 0 275  ARG A CZ   1 ? 
ATOM   4018 N NH1  A ARG A 1 260 ? 16.052  -2.686  -24.827 0.500 27.977 0 275  ARG A NH1  1 ? 
ATOM   4019 N NH1  B ARG A 1 260 ? 15.533  -4.140  -22.617 0.500 32.430 0 275  ARG A NH1  1 ? 
ATOM   4020 N NH2  A ARG A 1 260 ? 17.949  -3.916  -24.888 0.500 29.797 0 275  ARG A NH2  1 ? 
ATOM   4021 N NH2  B ARG A 1 260 ? 15.596  -4.638  -20.376 0.500 26.620 0 275  ARG A NH2  1 ? 
ATOM   4022 H H    A ARG A 1 260 ? 19.014  0.457   -19.026 0.500 16.024 0 275  ARG A H    1 c 
ATOM   4023 H H    B ARG A 1 260 ? 19.009  0.458   -19.030 0.500 16.456 0 275  ARG A H    1 c 
ATOM   4024 H HA   A ARG A 1 260 ? 18.094  2.096   -21.108 0.500 16.258 0 275  ARG A HA   1 c 
ATOM   4025 H HA   B ARG A 1 260 ? 18.105  2.129   -21.096 0.500 17.066 0 275  ARG A HA   1 c 
ATOM   4026 H HB2  A ARG A 1 260 ? 16.666  -0.072  -19.907 0.500 17.083 0 275  ARG A HB2  1 c 
ATOM   4027 H HB2  B ARG A 1 260 ? 16.680  -0.081  -19.959 0.500 18.654 0 275  ARG A HB2  1 c 
ATOM   4028 H HB3  A ARG A 1 260 ? 16.201  0.719   -21.196 0.500 17.057 0 275  ARG A HB3  1 c 
ATOM   4029 H HB3  B ARG A 1 260 ? 16.234  0.725   -21.251 0.500 18.627 0 275  ARG A HB3  1 c 
ATOM   4030 H HG2  A ARG A 1 260 ? 18.075  -0.178  -22.375 0.500 18.130 0 275  ARG A HG2  1 c 
ATOM   4031 H HG2  B ARG A 1 260 ? 18.180  -0.085  -22.377 0.500 20.496 0 275  ARG A HG2  1 c 
ATOM   4032 H HG3  A ARG A 1 260 ? 18.438  -1.032  -21.095 0.500 18.130 0 275  ARG A HG3  1 c 
ATOM   4033 H HG3  B ARG A 1 260 ? 18.529  -0.951  -21.102 0.500 20.496 0 275  ARG A HG3  1 c 
ATOM   4034 H HD2  A ARG A 1 260 ? 16.455  -2.287  -21.336 0.500 20.528 0 275  ARG A HD2  1 c 
ATOM   4035 H HD2  B ARG A 1 260 ? 16.191  -1.370  -22.662 0.500 23.936 0 275  ARG A HD2  1 c 
ATOM   4036 H HD3  A ARG A 1 260 ? 16.024  -1.399  -22.574 0.500 20.528 0 275  ARG A HD3  1 c 
ATOM   4037 H HD3  B ARG A 1 260 ? 17.509  -2.226  -22.832 0.500 23.936 0 275  ARG A HD3  1 c 
ATOM   4038 H HE   A ARG A 1 260 ? 18.263  -3.016  -22.710 0.500 23.042 0 275  ARG A HE   1 c 
ATOM   4039 H HE   B ARG A 1 260 ? 16.627  -2.441  -20.318 0.500 27.055 0 275  ARG A HE   1 c 
ATOM   4040 H HH11 A ARG A 1 260 ? 15.857  -2.978  -25.638 0.500 27.666 0 275  ARG A HH11 1 c 
ATOM   4041 H HH11 B ARG A 1 260 ? 15.124  -4.908  -22.775 0.500 31.545 0 275  ARG A HH11 1 c 
ATOM   4042 H HH12 A ARG A 1 260 ? 15.511  -2.124  -24.411 0.500 27.666 0 275  ARG A HH12 1 c 
ATOM   4043 H HH12 B ARG A 1 260 ? 15.711  -3.583  -23.280 0.500 31.545 0 275  ARG A HH12 1 c 
ATOM   4044 H HH21 A ARG A 1 260 ? 17.726  -4.188  -25.699 0.500 28.900 0 275  ARG A HH21 1 c 
ATOM   4045 H HH21 B ARG A 1 260 ? 15.187  -5.405  -20.537 0.500 27.516 0 275  ARG A HH21 1 c 
ATOM   4046 H HH22 A ARG A 1 260 ? 18.699  -4.194  -24.513 0.500 28.900 0 275  ARG A HH22 1 c 
ATOM   4047 H HH22 B ARG A 1 260 ? 15.817  -4.412  -19.551 0.500 27.516 0 275  ARG A HH22 1 c 
ATOM   4048 N N    . TYR A 1 261 ? 17.737  3.144   -18.413 1.000 14.660 0 276  TYR A N    1 ? 
ATOM   4049 C CA   . TYR A 1 261 ? 17.041  3.927   -17.373 1.000 14.508 0 276  TYR A CA   1 ? 
ATOM   4050 C C    . TYR A 1 261 ? 17.690  5.310   -17.293 1.000 13.214 0 276  TYR A C    1 ? 
ATOM   4051 O O    . TYR A 1 261 ? 18.426  5.655   -16.363 1.000 14.522 0 276  TYR A O    1 ? 
ATOM   4052 C CB   . TYR A 1 261 ? 17.022  3.212   -16.016 1.000 14.326 0 276  TYR A CB   1 ? 
ATOM   4053 C CG   . TYR A 1 261 ? 15.959  3.660   -15.027 1.000 14.597 0 276  TYR A CG   1 ? 
ATOM   4054 C CD1  . TYR A 1 261 ? 15.312  4.881   -15.118 1.000 13.968 0 276  TYR A CD1  1 ? 
ATOM   4055 C CD2  . TYR A 1 261 ? 15.603  2.826   -13.980 1.000 16.554 0 276  TYR A CD2  1 ? 
ATOM   4056 C CE1  . TYR A 1 261 ? 14.358  5.270   -14.194 1.000 14.771 0 276  TYR A CE1  1 ? 
ATOM   4057 C CE2  . TYR A 1 261 ? 14.689  3.234   -13.029 1.000 17.207 0 276  TYR A CE2  1 ? 
ATOM   4058 C CZ   . TYR A 1 261 ? 14.035  4.444   -13.142 1.000 15.716 0 276  TYR A CZ   1 ? 
ATOM   4059 O OH   . TYR A 1 261 ? 13.073  4.801   -12.205 1.000 15.442 0 276  TYR A OH   1 ? 
ATOM   4060 H H    . TYR A 1 261 ? 18.650  3.130   -18.420 1.000 14.957 0 276  TYR A H    1 c 
ATOM   4061 H HA   . TYR A 1 261 ? 16.098  4.052   -17.657 1.000 14.284 0 276  TYR A HA   1 c 
ATOM   4062 H HB2  . TYR A 1 261 ? 16.905  2.250   -16.181 1.000 14.428 0 276  TYR A HB2  1 c 
ATOM   4063 H HB3  . TYR A 1 261 ? 17.904  3.324   -15.597 1.000 14.423 0 276  TYR A HB3  1 c 
ATOM   4064 H HD1  . TYR A 1 261 ? 15.522  5.465   -15.828 1.000 14.328 0 276  TYR A HD1  1 c 
ATOM   4065 H HD2  . TYR A 1 261 ? 16.047  2.000   -13.871 1.000 16.188 0 276  TYR A HD2  1 c 
ATOM   4066 H HE1  . TYR A 1 261 ? 13.932  6.105   -14.281 1.000 14.814 0 276  TYR A HE1  1 c 
ATOM   4067 H HE2  . TYR A 1 261 ? 14.456  2.648   -12.328 1.000 16.641 0 276  TYR A HE2  1 c 
ATOM   4068 H HH   . TYR A 1 261 ? 12.301  4.526   -12.459 0.000 15.460 0 276  TYR A HH   1 c 
ATOM   4069 N N    . PRO A 1 262 ? 17.368  6.204   -18.261 1.000 13.719 0 277  PRO A N    1 ? 
ATOM   4070 C CA   . PRO A 1 262 ? 17.995  7.522   -18.297 1.000 14.614 0 277  PRO A CA   1 ? 
ATOM   4071 C C    . PRO A 1 262 ? 17.968  8.291   -16.998 1.000 14.321 0 277  PRO A C    1 ? 
ATOM   4072 O O    . PRO A 1 262 ? 18.979  8.837   -16.565 1.000 14.522 0 277  PRO A O    1 ? 
ATOM   4073 C CB   . PRO A 1 262 ? 17.219  8.214   -19.428 1.000 14.023 0 277  PRO A CB   1 ? 
ATOM   4074 C CG   . PRO A 1 262 ? 16.809  7.096   -20.362 1.000 14.610 0 277  PRO A CG   1 ? 
ATOM   4075 C CD   . PRO A 1 262 ? 16.521  5.918   -19.425 1.000 14.403 0 277  PRO A CD   1 ? 
ATOM   4076 H HA   . PRO A 1 262 ? 18.936  7.403   -18.581 1.000 14.274 0 277  PRO A HA   1 c 
ATOM   4077 H HB2  . PRO A 1 262 ? 16.426  8.681   -19.074 1.000 14.283 0 277  PRO A HB2  1 c 
ATOM   4078 H HB3  . PRO A 1 262 ? 17.788  8.869   -19.894 1.000 14.290 0 277  PRO A HB3  1 c 
ATOM   4079 H HG2  . PRO A 1 262 ? 16.009  7.340   -20.873 1.000 14.429 0 277  PRO A HG2  1 c 
ATOM   4080 H HG3  . PRO A 1 262 ? 17.532  6.878   -20.987 1.000 14.429 0 277  PRO A HG3  1 c 
ATOM   4081 H HD2  . PRO A 1 262 ? 15.571  5.887   -19.175 1.000 14.302 0 277  PRO A HD2  1 c 
ATOM   4082 H HD3  . PRO A 1 262 ? 16.772  5.072   -19.848 1.000 14.312 0 277  PRO A HD3  1 c 
ATOM   4083 N N    . MET A 1 263 ? 16.786  8.393   -16.368 1.000 13.743 0 278  MET A N    1 ? 
ATOM   4084 C CA   . MET A 1 263 ? 16.660  9.224   -15.168 1.000 13.873 0 278  MET A CA   1 ? 
ATOM   4085 C C    . MET A 1 263 ? 17.479  8.657   -14.005 1.000 14.394 0 278  MET A C    1 ? 
ATOM   4086 O O    . MET A 1 263 ? 17.922  9.432   -13.146 1.000 15.803 0 278  MET A O    1 ? 
ATOM   4087 C CB   . MET A 1 263 ? 15.182  9.442   -14.778 1.000 14.961 0 278  MET A CB   1 ? 
ATOM   4088 C CG   . MET A 1 263 ? 14.474  10.359  -15.771 1.000 15.756 0 278  MET A CG   1 ? 
ATOM   4089 S SD   . MET A 1 263 ? 12.761  10.719  -15.324 1.000 17.715 0 278  MET A SD   1 ? 
ATOM   4090 C CE   . MET A 1 263 ? 11.898  9.226   -15.700 1.000 19.449 0 278  MET A CE   1 ? 
ATOM   4091 H H    . MET A 1 263 ? 16.053  7.948   -16.685 1.000 13.919 0 278  MET A H    1 c 
ATOM   4092 H HA   . MET A 1 263 ? 17.050  10.108  -15.387 1.000 14.148 0 278  MET A HA   1 c 
ATOM   4093 H HB2  . MET A 1 263 ? 14.725  8.575   -14.751 1.000 14.883 0 278  MET A HB2  1 c 
ATOM   4094 H HB3  . MET A 1 263 ? 15.141  9.838   -13.881 1.000 14.881 0 278  MET A HB3  1 c 
ATOM   4095 H HG2  . MET A 1 263 ? 14.964  11.203  -15.832 1.000 15.901 0 278  MET A HG2  1 c 
ATOM   4096 H HG3  . MET A 1 263 ? 14.486  9.944   -16.653 1.000 15.913 0 278  MET A HG3  1 c 
ATOM   4097 H HE1  . MET A 1 263 ? 10.960  9.322   -15.455 1.000 18.954 0 278  MET A HE1  1 c 
ATOM   4098 H HE2  . MET A 1 263 ? 11.968  9.042   -16.655 1.000 18.983 0 278  MET A HE2  1 c 
ATOM   4099 H HE3  . MET A 1 263 ? 12.291  8.489   -15.197 1.000 18.983 0 278  MET A HE3  1 c 
ATOM   4100 N N    . ALA A 1 264 ? 17.630  7.326   -13.915 1.000 14.599 0 279  ALA A N    1 ? 
ATOM   4101 C CA   . ALA A 1 264 ? 18.436  6.735   -12.850 1.000 14.967 0 279  ALA A CA   1 ? 
ATOM   4102 C C    . ALA A 1 264 ? 19.887  7.215   -12.952 1.000 14.350 0 279  ALA A C    1 ? 
ATOM   4103 O O    . ALA A 1 264 ? 20.558  7.444   -11.935 1.000 14.954 0 279  ALA A O    1 ? 
ATOM   4104 C CB   . ALA A 1 264 ? 18.392  5.194   -12.886 1.000 15.000 0 279  ALA A CB   1 ? 
ATOM   4105 H H    . ALA A 1 264 ? 17.226  6.777   -14.523 1.000 14.618 0 279  ALA A H    1 c 
ATOM   4106 H HA   . ALA A 1 264 ? 18.069  7.047   -11.977 1.000 14.791 0 279  ALA A HA   1 c 
ATOM   4107 H HB1  . ALA A 1 264 ? 17.476  4.891   -12.777 1.000 14.990 0 279  ALA A HB1  1 c 
ATOM   4108 H HB2  . ALA A 1 264 ? 18.736  4.877   -13.738 1.000 14.990 0 279  ALA A HB2  1 c 
ATOM   4109 H HB3  . ALA A 1 264 ? 18.938  4.835   -12.167 1.000 14.990 0 279  ALA A HB3  1 c 
ATOM   4110 N N    . LEU A 1 265 ? 20.377  7.358   -14.184 1.000 15.276 0 280  LEU A N    1 ? 
ATOM   4111 C CA   . LEU A 1 265 ? 21.737  7.873   -14.388 1.000 16.098 0 280  LEU A CA   1 ? 
ATOM   4112 C C    . LEU A 1 265 ? 21.852  9.345   -13.961 1.000 17.257 0 280  LEU A C    1 ? 
ATOM   4113 O O    . LEU A 1 265 ? 22.853  9.780   -13.401 1.000 16.257 0 280  LEU A O    1 ? 
ATOM   4114 C CB   . LEU A 1 265 ? 22.191  7.629   -15.826 1.000 16.836 0 280  LEU A CB   1 ? 
ATOM   4115 C CG   . LEU A 1 265 ? 22.394  6.162   -16.210 1.000 17.967 0 280  LEU A CG   1 ? 
ATOM   4116 C CD1  . LEU A 1 265 ? 22.276  5.915   -17.689 1.000 18.774 0 280  LEU A CD1  1 ? 
ATOM   4117 C CD2  . LEU A 1 265 ? 23.787  5.712   -15.705 1.000 17.830 0 280  LEU A CD2  1 ? 
ATOM   4118 H H    . LEU A 1 265 ? 19.872  7.128   -14.911 1.000 15.230 0 280  LEU A H    1 c 
ATOM   4119 H HA   . LEU A 1 265 ? 22.335  7.356   -13.790 1.000 16.265 0 280  LEU A HA   1 c 
ATOM   4120 H HB2  . LEU A 1 265 ? 21.519  8.019   -16.431 1.000 16.912 0 280  LEU A HB2  1 c 
ATOM   4121 H HB3  . LEU A 1 265 ? 23.038  8.110   -15.968 1.000 16.925 0 280  LEU A HB3  1 c 
ATOM   4122 H HG   . LEU A 1 265 ? 21.705  5.619   -15.748 1.000 17.862 0 280  LEU A HG   1 c 
ATOM   4123 H HD11 . LEU A 1 265 ? 21.390  6.177   -17.993 1.000 18.530 0 280  LEU A HD11 1 c 
ATOM   4124 H HD12 . LEU A 1 265 ? 22.414  4.970   -17.873 1.000 18.530 0 280  LEU A HD12 1 c 
ATOM   4125 H HD13 . LEU A 1 265 ? 22.946  6.437   -18.161 1.000 18.530 0 280  LEU A HD13 1 c 
ATOM   4126 H HD21 . LEU A 1 265 ? 23.835  5.822   -14.740 1.000 17.856 0 280  LEU A HD21 1 c 
ATOM   4127 H HD22 . LEU A 1 265 ? 24.477  6.253   -16.126 1.000 17.860 0 280  LEU A HD22 1 c 
ATOM   4128 H HD23 . LEU A 1 265 ? 23.928  4.777   -15.930 1.000 17.865 0 280  LEU A HD23 1 c 
ATOM   4129 N N    . GLY A 1 266 ? 20.816  10.162  -14.228 1.000 14.801 0 281  GLY A N    1 ? 
ATOM   4130 C CA   . GLY A 1 266 ? 20.792  11.509  -13.711 1.000 15.700 0 281  GLY A CA   1 ? 
ATOM   4131 C C    . GLY A 1 266 ? 20.757  11.570  -12.199 1.000 17.131 0 281  GLY A C    1 ? 
ATOM   4132 O O    . GLY A 1 266 ? 21.431  12.399  -11.632 1.000 16.712 0 281  GLY A O    1 ? 
ATOM   4133 H H    . GLY A 1 266 ? 20.122  9.869   -14.744 1.000 15.560 0 281  GLY A H    1 c 
ATOM   4134 H HA2  . GLY A 1 266 ? 21.590  11.988  -14.037 1.000 15.795 0 281  GLY A HA2  1 c 
ATOM   4135 H HA3  . GLY A 1 266 ? 20.000  11.971  -14.072 1.000 15.789 0 281  GLY A HA3  1 c 
ATOM   4136 N N    . ASN A 1 267 ? 20.003  10.680  -11.534 1.000 16.517 0 282  ASN A N    1 ? 
ATOM   4137 C CA   . ASN A 1 267 ? 19.939  10.607  -10.078 1.000 15.801 0 282  ASN A CA   1 ? 
ATOM   4138 C C    . ASN A 1 267 ? 21.336  10.289  -9.545  1.000 17.639 0 282  ASN A C    1 ? 
ATOM   4139 O O    . ASN A 1 267 ? 21.786  10.909  -8.589  1.000 16.942 0 282  ASN A O    1 ? 
ATOM   4140 C CB   . ASN A 1 267 ? 18.905  9.560   -9.707  1.000 16.296 0 282  ASN A CB   1 ? 
ATOM   4141 C CG   . ASN A 1 267 ? 18.578  9.414   -8.242  1.000 19.893 0 282  ASN A CG   1 ? 
ATOM   4142 O OD1  . ASN A 1 267 ? 19.181  10.012  -7.322  1.000 22.594 0 282  ASN A OD1  1 ? 
ATOM   4143 N ND2  . ASN A 1 267 ? 17.630  8.543   -8.005  1.000 18.746 0 282  ASN A ND2  1 ? 
ATOM   4144 H H    . ASN A 1 267 ? 19.500  10.090  -12.018 1.000 16.481 0 282  ASN A H    1 c 
ATOM   4145 H HA   . ASN A 1 267 ? 19.640  11.476  -9.726  1.000 16.352 0 282  ASN A HA   1 c 
ATOM   4146 H HB2  . ASN A 1 267 ? 18.076  9.767   -10.184 1.000 16.943 0 282  ASN A HB2  1 c 
ATOM   4147 H HB3  . ASN A 1 267 ? 19.217  8.693   -10.036 1.000 16.937 0 282  ASN A HB3  1 c 
ATOM   4148 H HD21 . ASN A 1 267 ? 17.412  7.942   -8.621  1.000 19.074 0 282  ASN A HD21 1 c 
ATOM   4149 H HD22 . ASN A 1 267 ? 17.207  8.553   -7.226  1.000 19.111 0 282  ASN A HD22 1 c 
ATOM   4150 N N    . LEU A 1 268 ? 22.005  9.332   -10.179 1.000 15.920 0 283  LEU A N    1 ? 
ATOM   4151 C CA   . LEU A 1 268 ? 23.343  8.919   -9.731  1.000 16.726 0 283  LEU A CA   1 ? 
ATOM   4152 C C    . LEU A 1 268 ? 24.323  10.085  -9.879  1.000 18.207 0 283  LEU A C    1 ? 
ATOM   4153 O O    . LEU A 1 268 ? 25.123  10.375  -8.968  1.000 17.790 0 283  LEU A O    1 ? 
ATOM   4154 C CB   . LEU A 1 268 ? 23.783  7.681   -10.499 1.000 17.406 0 283  LEU A CB   1 ? 
ATOM   4155 C CG   . LEU A 1 268 ? 25.161  7.130   -10.143 1.000 16.817 0 283  LEU A CG   1 ? 
ATOM   4156 C CD1  . LEU A 1 268 ? 25.268  6.941   -8.648  1.000 18.435 0 283  LEU A CD1  1 ? 
ATOM   4157 C CD2  . LEU A 1 268 ? 25.373  5.864   -10.884 1.000 17.979 0 283  LEU A CD2  1 ? 
ATOM   4158 H H    . LEU A 1 268 ? 21.630  8.915   -10.902 1.000 16.497 0 283  LEU A H    1 c 
ATOM   4159 H HA   . LEU A 1 268 ? 23.280  8.693   -8.769  1.000 16.966 0 283  LEU A HA   1 c 
ATOM   4160 H HB2  . LEU A 1 268 ? 23.116  6.972   -10.346 1.000 17.121 0 283  LEU A HB2  1 c 
ATOM   4161 H HB3  . LEU A 1 268 ? 23.773  7.896   -11.460 1.000 17.115 0 283  LEU A HB3  1 c 
ATOM   4162 H HG   . LEU A 1 268 ? 25.849  7.784   -10.432 1.000 17.438 0 283  LEU A HG   1 c 
ATOM   4163 H HD11 . LEU A 1 268 ? 25.398  7.803   -8.218  1.000 17.927 0 283  LEU A HD11 1 c 
ATOM   4164 H HD12 . LEU A 1 268 ? 26.023  6.364   -8.446  1.000 17.947 0 283  LEU A HD12 1 c 
ATOM   4165 H HD13 . LEU A 1 268 ? 24.452  6.533   -8.312  1.000 17.935 0 283  LEU A HD13 1 c 
ATOM   4166 H HD21 . LEU A 1 268 ? 25.306  6.031   -11.839 1.000 17.618 0 283  LEU A HD21 1 c 
ATOM   4167 H HD22 . LEU A 1 268 ? 24.698  5.217   -10.621 1.000 17.615 0 283  LEU A HD22 1 c 
ATOM   4168 H HD23 . LEU A 1 268 ? 26.255  5.511   -10.679 1.000 17.615 0 283  LEU A HD23 1 c 
ATOM   4169 N N    . ALA A 1 269 ? 24.229  10.803  -10.999 1.000 16.190 0 284  ALA A N    1 ? 
ATOM   4170 C CA   . ALA A 1 269 ? 25.090  11.973  -11.226 1.000 16.122 0 284  ALA A CA   1 ? 
ATOM   4171 C C    . ALA A 1 269 ? 24.875  13.038  -10.156 1.000 16.918 0 284  ALA A C    1 ? 
ATOM   4172 O O    . ALA A 1 269 ? 25.813  13.598  -9.594  1.000 18.272 0 284  ALA A O    1 ? 
ATOM   4173 C CB   . ALA A 1 269 ? 24.784  12.521  -12.596 1.000 16.852 0 284  ALA A CB   1 ? 
ATOM   4174 H H    . ALA A 1 269 ? 23.626  10.564  -11.644 1.000 16.633 0 284  ALA A H    1 c 
ATOM   4175 H HA   . ALA A 1 269 ? 26.041  11.677  -11.192 1.000 16.411 0 284  ALA A HA   1 c 
ATOM   4176 H HB1  . ALA A 1 269 ? 24.891  11.820  -13.260 1.000 16.663 0 284  ALA A HB1  1 c 
ATOM   4177 H HB2  . ALA A 1 269 ? 23.870  12.847  -12.620 1.000 16.641 0 284  ALA A HB2  1 c 
ATOM   4178 H HB3  . ALA A 1 269 ? 25.391  13.252  -12.799 1.000 16.642 0 284  ALA A HB3  1 c 
ATOM   4179 N N    . ASP A 1 270 ? 23.593  13.296  -9.800  1.000 17.005 0 285  ASP A N    1 ? 
ATOM   4180 C CA   . ASP A 1 270 ? 23.269  14.254  -8.763  1.000 17.402 0 285  ASP A CA   1 ? 
ATOM   4181 C C    . ASP A 1 270 ? 23.882  13.833  -7.422  1.000 18.287 0 285  ASP A C    1 ? 
ATOM   4182 O O    . ASP A 1 270 ? 24.325  14.721  -6.646  1.000 19.468 0 285  ASP A O    1 ? 
ATOM   4183 C CB   . ASP A 1 270 ? 21.762  14.424  -8.598  1.000 18.328 0 285  ASP A CB   1 ? 
ATOM   4184 C CG   . ASP A 1 270 ? 21.023  15.193  -9.665  1.000 20.959 0 285  ASP A CG   1 ? 
ATOM   4185 O OD1  . ASP A 1 270 ? 21.672  15.791  -10.546 1.000 19.018 0 285  ASP A OD1  1 ? 
ATOM   4186 O OD2  . ASP A 1 270 ? 19.749  15.204  -9.550  1.000 22.358 0 285  ASP A OD2  1 ? 
ATOM   4187 H H    . ASP A 1 270 ? 22.911  12.861  -10.227 1.000 17.080 0 285  ASP A H    1 c 
ATOM   4188 H HA   . ASP A 1 270 ? 23.649  15.125  -9.020  1.000 17.659 0 285  ASP A HA   1 c 
ATOM   4189 H HB2  . ASP A 1 270 ? 21.359  13.533  -8.541  1.000 18.667 0 285  ASP A HB2  1 c 
ATOM   4190 H HB3  . ASP A 1 270 ? 21.596  14.876  -7.744  1.000 18.683 0 285  ASP A HB3  1 c 
ATOM   4191 N N    . LEU A 1 271 ? 23.828  12.536  -7.105  1.000 17.107 0 286  LEU A N    1 ? 
ATOM   4192 C CA   . LEU A 1 271 ? 24.388  12.062  -5.844  1.000 18.103 0 286  LEU A CA   1 ? 
ATOM   4193 C C    . LEU A 1 271 ? 25.918  12.228  -5.830  1.000 19.082 0 286  LEU A C    1 ? 
ATOM   4194 O O    . LEU A 1 271 ? 26.508  12.550  -4.790  1.000 20.343 0 286  LEU A O    1 ? 
ATOM   4195 C CB   . LEU A 1 271 ? 23.969  10.615  -5.616  1.000 19.085 0 286  LEU A CB   1 ? 
ATOM   4196 C CG   . LEU A 1 271 ? 22.497  10.372  -5.260  1.000 19.188 0 286  LEU A CG   1 ? 
ATOM   4197 C CD1  . LEU A 1 271 ? 22.106  8.914   -5.462  1.000 18.291 0 286  LEU A CD1  1 ? 
ATOM   4198 C CD2  . LEU A 1 271 ? 22.200  10.790  -3.842  1.000 19.410 0 286  LEU A CD2  1 ? 
ATOM   4199 H H    . LEU A 1 271 ? 23.435  11.938  -7.674  1.000 17.617 0 286  LEU A H    1 c 
ATOM   4200 H HA   . LEU A 1 271 ? 24.013  12.621  -5.116  1.000 18.270 0 286  LEU A HA   1 c 
ATOM   4201 H HB2  . LEU A 1 271 ? 24.179  10.104  -6.431  1.000 18.866 0 286  LEU A HB2  1 c 
ATOM   4202 H HB3  . LEU A 1 271 ? 24.526  10.247  -4.891  1.000 18.877 0 286  LEU A HB3  1 c 
ATOM   4203 H HG   . LEU A 1 271 ? 21.939  10.925  -5.865  1.000 19.041 0 286  LEU A HG   1 c 
ATOM   4204 H HD11 . LEU A 1 271 ? 22.264  8.660   -6.387  1.000 18.554 0 286  LEU A HD11 1 c 
ATOM   4205 H HD12 . LEU A 1 271 ? 21.165  8.798   -5.252  1.000 18.564 0 286  LEU A HD12 1 c 
ATOM   4206 H HD13 . LEU A 1 271 ? 22.640  8.350   -4.878  1.000 18.554 0 286  LEU A HD13 1 c 
ATOM   4207 H HD21 . LEU A 1 271 ? 22.351  11.745  -3.746  1.000 19.336 0 286  LEU A HD21 1 c 
ATOM   4208 H HD22 . LEU A 1 271 ? 22.783  10.307  -3.232  1.000 19.342 0 286  LEU A HD22 1 c 
ATOM   4209 H HD23 . LEU A 1 271 ? 21.273  10.587  -3.632  1.000 19.342 0 286  LEU A HD23 1 c 
ATOM   4210 N N    . GLU A 1 272 ? 26.557  11.960  -6.972  1.000 18.430 0 287  GLU A N    1 ? 
ATOM   4211 C CA   . GLU A 1 272 ? 28.008  12.084  -7.117  1.000 18.828 0 287  GLU A CA   1 ? 
ATOM   4212 C C    . GLU A 1 272 ? 28.421  13.550  -6.979  1.000 22.565 0 287  GLU A C    1 ? 
ATOM   4213 O O    . GLU A 1 272 ? 29.504  13.869  -6.466  1.000 23.079 0 287  GLU A O    1 ? 
ATOM   4214 C CB   . GLU A 1 272 ? 28.490  11.535  -8.460  1.000 18.842 0 287  GLU A CB   1 ? 
ATOM   4215 C CG   . GLU A 1 272 ? 28.549  10.014  -8.516  1.000 20.016 0 287  GLU A CG   1 ? 
ATOM   4216 C CD   . GLU A 1 272 ? 29.509  9.398   -7.503  1.000 23.074 0 287  GLU A CD   1 ? 
ATOM   4217 O OE1  . GLU A 1 272 ? 30.699  9.813   -7.587  1.000 21.691 0 287  GLU A OE1  1 ? 
ATOM   4218 O OE2  . GLU A 1 272 ? 29.107  8.536   -6.656  1.000 20.326 0 287  GLU A OE2  1 ? 
ATOM   4219 H H    . GLU A 1 272 ? 26.071  11.681  -7.694  1.000 18.662 0 287  GLU A H    1 c 
ATOM   4220 H HA   . GLU A 1 272 ? 28.436  11.569  -6.387  1.000 19.408 0 287  GLU A HA   1 c 
ATOM   4221 H HB2  . GLU A 1 272 ? 27.890  11.855  -9.165  1.000 19.110 0 287  GLU A HB2  1 c 
ATOM   4222 H HB3  . GLU A 1 272 ? 29.384  11.892  -8.645  1.000 19.165 0 287  GLU A HB3  1 c 
ATOM   4223 H HG2  . GLU A 1 272 ? 27.652  9.653   -8.357  1.000 20.378 0 287  GLU A HG2  1 c 
ATOM   4224 H HG3  . GLU A 1 272 ? 28.826  9.738   -9.416  1.000 20.379 0 287  GLU A HG3  1 c 
ATOM   4225 N N    . GLU A 1 273 ? 27.587  14.468  -7.454  1.000 21.455 0 288  GLU A N    1 ? 
ATOM   4226 C CA   . GLU A 1 273 ? 27.898  15.884  -7.299  1.000 24.140 0 288  GLU A CA   1 ? 
ATOM   4227 C C    . GLU A 1 273 ? 27.958  16.239  -5.810  1.000 24.536 0 288  GLU A C    1 ? 
ATOM   4228 O O    . GLU A 1 273 ? 28.834  16.979  -5.366  1.000 24.539 0 288  GLU A O    1 ? 
ATOM   4229 C CB   . GLU A 1 273 ? 26.871  16.767  -8.024  1.000 23.851 0 288  GLU A CB   1 ? 
ATOM   4230 C CG   . GLU A 1 273 ? 27.118  18.267  -7.868  1.000 27.933 0 288  GLU A CG   1 ? 
ATOM   4231 C CD   . GLU A 1 273 ? 25.966  19.152  -8.344  1.000 30.538 0 288  GLU A CD   1 ? 
ATOM   4232 O OE1  . GLU A 1 273 ? 24.883  18.640  -8.618  1.000 30.362 0 288  GLU A OE1  1 ? 
ATOM   4233 O OE2  . GLU A 1 273 ? 26.169  20.371  -8.443  1.000 36.638 0 288  GLU A OE2  1 ? 
ATOM   4234 H H    . GLU A 1 273 ? 26.821  14.222  -7.887  1.000 22.251 0 288  GLU A H    1 c 
ATOM   4235 H HA   . GLU A 1 273 ? 28.790  16.051  -7.698  1.000 23.600 0 288  GLU A HA   1 c 
ATOM   4236 H HB2  . GLU A 1 273 ? 26.883  16.543  -8.978  1.000 24.793 0 288  GLU A HB2  1 c 
ATOM   4237 H HB3  . GLU A 1 273 ? 25.980  16.555  -7.679  1.000 24.791 0 288  GLU A HB3  1 c 
ATOM   4238 H HG2  . GLU A 1 273 ? 27.290  18.469  -6.925  1.000 27.471 0 288  GLU A HG2  1 c 
ATOM   4239 H HG3  . GLU A 1 273 ? 27.924  18.511  -8.372  1.000 27.496 0 288  GLU A HG3  1 c 
ATOM   4240 N N    . LEU A 1 274 ? 27.003  15.714  -5.049  1.000 23.205 0 289  LEU A N    1 ? 
ATOM   4241 C CA   . LEU A 1 274 ? 26.925  15.982  -3.623  1.000 26.405 0 289  LEU A CA   1 ? 
ATOM   4242 C C    . LEU A 1 274 ? 28.101  15.349  -2.901  1.000 25.155 0 289  LEU A C    1 ? 
ATOM   4243 O O    . LEU A 1 274 ? 28.642  15.960  -1.997  1.000 26.378 0 289  LEU A O    1 ? 
ATOM   4244 C CB   . LEU A 1 274 ? 25.612  15.412  -3.101  1.000 30.124 0 289  LEU A CB   1 ? 
ATOM   4245 C CG   . LEU A 1 274 ? 25.015  16.045  -1.841  1.000 38.704 0 289  LEU A CG   1 ? 
ATOM   4246 C CD1  . LEU A 1 274 ? 24.454  17.407  -2.194  1.000 41.553 0 289  LEU A CD1  1 ? 
ATOM   4247 C CD2  . LEU A 1 274 ? 23.923  15.106  -1.300  1.000 40.396 0 289  LEU A CD2  1 ? 
ATOM   4248 H H    . LEU A 1 274 ? 26.376  15.169  -5.430  1.000 24.281 0 289  LEU A H    1 c 
ATOM   4249 H HA   . LEU A 1 274 ? 26.944  16.962  -3.481  1.000 26.258 0 289  LEU A HA   1 c 
ATOM   4250 H HB2  . LEU A 1 274 ? 24.943  15.478  -3.821  1.000 30.956 0 289  LEU A HB2  1 c 
ATOM   4251 H HB3  . LEU A 1 274 ? 25.745  14.451  -2.929  1.000 31.009 0 289  LEU A HB3  1 c 
ATOM   4252 H HG   . LEU A 1 274 ? 25.729  16.148  -1.161  1.000 37.732 0 289  LEU A HG   1 c 
ATOM   4253 H HD11 . LEU A 1 274 ? 25.172  17.987  -2.497  1.000 40.450 0 289  LEU A HD11 1 c 
ATOM   4254 H HD12 . LEU A 1 274 ? 24.033  17.798  -1.410  1.000 40.616 0 289  LEU A HD12 1 c 
ATOM   4255 H HD13 . LEU A 1 274 ? 23.794  17.313  -2.902  1.000 40.557 0 289  LEU A HD13 1 c 
ATOM   4256 H HD21 . LEU A 1 274 ? 24.319  14.252  -1.059  1.000 39.824 0 289  LEU A HD21 1 c 
ATOM   4257 H HD22 . LEU A 1 274 ? 23.247  14.967  -1.984  1.000 39.878 0 289  LEU A HD22 1 c 
ATOM   4258 H HD23 . LEU A 1 274 ? 23.512  15.504  -0.515  1.000 39.878 0 289  LEU A HD23 1 c 
ATOM   4259 N N    . GLU A 1 275 ? 28.457  14.111  -3.240  1.000 22.414 0 290  GLU A N    1 ? 
ATOM   4260 C CA   . GLU A 1 275 ? 29.500  13.412  -2.490  1.000 25.205 0 290  GLU A CA   1 ? 
ATOM   4261 C C    . GLU A 1 275 ? 30.191  12.426  -3.409  1.000 21.239 0 290  GLU A C    1 ? 
ATOM   4262 O O    . GLU A 1 275 ? 29.723  11.323  -3.618  1.000 22.313 0 290  GLU A O    1 ? 
ATOM   4263 C CB   . GLU A 1 275 ? 28.905  12.744  -1.257  1.000 26.878 0 290  GLU A CB   1 ? 
ATOM   4264 C CG   . GLU A 1 275 ? 29.931  11.911  -0.506  1.000 33.969 0 290  GLU A CG   1 ? 
ATOM   4265 C CD   . GLU A 1 275 ? 30.556  12.684  0.609   1.000 45.549 0 290  GLU A CD   1 ? 
ATOM   4266 O OE1  . GLU A 1 275 ? 30.530  12.118  1.728   1.000 64.416 0 290  GLU A OE1  1 ? 
ATOM   4267 O OE2  . GLU A 1 275 ? 31.033  13.814  0.366   1.000 50.603 0 290  GLU A OE2  1 ? 
ATOM   4268 H H    . GLU A 1 275 ? 28.047  13.688  -3.939  1.000 23.649 0 290  GLU A H    1 c 
ATOM   4269 H HA   . GLU A 1 275 ? 30.164  14.077  -2.184  1.000 24.292 0 290  GLU A HA   1 c 
ATOM   4270 H HB2  . GLU A 1 275 ? 28.542  13.435  -0.664  1.000 28.022 0 290  GLU A HB2  1 c 
ATOM   4271 H HB3  . GLU A 1 275 ? 28.163  12.167  -1.535  1.000 27.960 0 290  GLU A HB3  1 c 
ATOM   4272 H HG2  . GLU A 1 275 ? 29.495  11.114  -0.137  1.000 34.603 0 290  GLU A HG2  1 c 
ATOM   4273 H HG3  . GLU A 1 275 ? 30.635  11.617  -1.121  1.000 34.296 0 290  GLU A HG3  1 c 
ATOM   4274 N N    . PRO A 1 276 ? 31.267  12.826  -4.116  1.000 22.881 0 291  PRO A N    1 ? 
ATOM   4275 C CA   . PRO A 1 276 ? 31.841  11.981  -5.149  1.000 22.078 0 291  PRO A CA   1 ? 
ATOM   4276 C C    . PRO A 1 276 ? 32.518  10.731  -4.610  1.000 24.606 0 291  PRO A C    1 ? 
ATOM   4277 O O    . PRO A 1 276 ? 33.121  10.782  -3.543  1.000 28.659 0 291  PRO A O    1 ? 
ATOM   4278 C CB   . PRO A 1 276 ? 32.813  12.887  -5.895  1.000 26.960 0 291  PRO A CB   1 ? 
ATOM   4279 C CG   . PRO A 1 276 ? 33.106  13.978  -4.929  1.000 28.288 0 291  PRO A CG   1 ? 
ATOM   4280 C CD   . PRO A 1 276 ? 31.883  14.150  -4.044  1.000 26.293 0 291  PRO A CD   1 ? 
ATOM   4281 H HA   . PRO A 1 276 ? 31.114  11.717  -5.766  1.000 23.490 0 291  PRO A HA   1 c 
ATOM   4282 H HB2  . PRO A 1 276 ? 33.636  12.400  -6.138  1.000 26.072 0 291  PRO A HB2  1 c 
ATOM   4283 H HB3  . PRO A 1 276 ? 32.400  13.245  -6.715  1.000 26.119 0 291  PRO A HB3  1 c 
ATOM   4284 H HG2  . PRO A 1 276 ? 33.889  13.749  -4.385  1.000 27.519 0 291  PRO A HG2  1 c 
ATOM   4285 H HG3  . PRO A 1 276 ? 33.298  14.812  -5.407  1.000 27.519 0 291  PRO A HG3  1 c 
ATOM   4286 H HD2  . PRO A 1 276 ? 32.142  14.375  -3.123  1.000 25.856 0 291  PRO A HD2  1 c 
ATOM   4287 H HD3  . PRO A 1 276 ? 31.283  14.844  -4.396  1.000 25.867 0 291  PRO A HD3  1 c 
ATOM   4288 N N    . THR A 1 277 ? 32.368  9.634   -5.344  1.000 22.880 0 292  THR A N    1 ? 
ATOM   4289 C CA   . THR A 1 277 ? 32.922  8.341   -4.991  1.000 23.510 0 292  THR A CA   1 ? 
ATOM   4290 C C    . THR A 1 277 ? 34.273  8.226   -5.690  1.000 27.332 0 292  THR A C    1 ? 
ATOM   4291 O O    . THR A 1 277 ? 34.347  8.307   -6.920  1.000 26.397 0 292  THR A O    1 ? 
ATOM   4292 C CB   . THR A 1 277 ? 31.968  7.225   -5.410  1.000 23.930 0 292  THR A CB   1 ? 
ATOM   4293 O OG1  . THR A 1 277 ? 30.651  7.413   -4.863  1.000 21.336 0 292  THR A OG1  1 ? 
ATOM   4294 C CG2  . THR A 1 277 ? 32.519  5.845   -5.090  1.000 25.046 0 292  THR A CG2  1 ? 
ATOM   4295 H H    . THR A 1 277 ? 31.897  9.697   -6.124  1.000 23.416 0 292  THR A H    1 c 
ATOM   4296 H HA   . THR A 1 277 ? 33.048  8.302   -4.020  1.000 24.246 0 292  THR A HA   1 c 
ATOM   4297 H HB   . THR A 1 277 ? 31.892  7.266   -6.394  1.000 23.542 0 292  THR A HB   1 c 
ATOM   4298 H HG1  . THR A 1 277 ? 30.691  7.425   -4.001  0.000 21.330 0 292  THR A HG1  1 c 
ATOM   4299 H HG21 . THR A 1 277 ? 31.830  5.177   -5.245  1.000 24.714 0 292  THR A HG21 1 c 
ATOM   4300 H HG22 . THR A 1 277 ? 32.795  5.814   -4.158  1.000 24.714 0 292  THR A HG22 1 c 
ATOM   4301 H HG23 . THR A 1 277 ? 33.283  5.658   -5.660  1.000 24.724 0 292  THR A HG23 1 c 
ATOM   4302 N N    . PRO A 1 278 ? 35.391  7.960   -4.953  1.000 28.204 0 293  PRO A N    1 ? 
ATOM   4303 C CA   . PRO A 1 278 ? 36.685  7.780   -5.616  1.000 29.434 0 293  PRO A CA   1 ? 
ATOM   4304 C C    . PRO A 1 278 ? 36.628  6.679   -6.663  1.000 25.843 0 293  PRO A C    1 ? 
ATOM   4305 O O    . PRO A 1 278 ? 36.053  5.613   -6.447  1.000 29.940 0 293  PRO A O    1 ? 
ATOM   4306 C CB   . PRO A 1 278 ? 37.664  7.469   -4.449  1.000 32.785 0 293  PRO A CB   1 ? 
ATOM   4307 C CG   . PRO A 1 278 ? 36.965  7.931   -3.217  1.000 33.180 0 293  PRO A CG   1 ? 
ATOM   4308 C CD   . PRO A 1 278 ? 35.466  7.822   -3.486  1.000 32.165 0 293  PRO A CD   1 ? 
ATOM   4309 H HA   . PRO A 1 278 ? 36.943  8.635   -6.042  1.000 29.038 0 293  PRO A HA   1 c 
ATOM   4310 H HB2  . PRO A 1 278 ? 37.855  6.503   -4.400  1.000 32.070 0 293  PRO A HB2  1 c 
ATOM   4311 H HB3  . PRO A 1 278 ? 38.514  7.951   -4.569  1.000 32.102 0 293  PRO A HB3  1 c 
ATOM   4312 H HG2  . PRO A 1 278 ? 37.215  7.371   -2.452  1.000 32.859 0 293  PRO A HG2  1 c 
ATOM   4313 H HG3  . PRO A 1 278 ? 37.207  8.858   -3.013  1.000 32.859 0 293  PRO A HG3  1 c 
ATOM   4314 H HD2  . PRO A 1 278 ? 35.115  6.952   -3.191  1.000 31.395 0 293  PRO A HD2  1 c 
ATOM   4315 H HD3  . PRO A 1 278 ? 34.975  8.542   -3.033  1.000 31.311 0 293  PRO A HD3  1 c 
ATOM   4316 N N    . GLY A 1 279 ? 37.191  6.990   -7.839  1.000 27.891 0 294  GLY A N    1 ? 
ATOM   4317 C CA   . GLY A 1 279 ? 37.402  6.058   -8.918  1.000 27.692 0 294  GLY A CA   1 ? 
ATOM   4318 C C    . GLY A 1 279 ? 36.148  5.885   -9.765  1.000 31.320 0 294  GLY A C    1 ? 
ATOM   4319 O O    . GLY A 1 279 ? 36.042  4.902   -10.491 1.000 36.097 0 294  GLY A O    1 ? 
ATOM   4320 H H    . GLY A 1 279 ? 37.459  7.854   -7.968  1.000 27.376 0 294  GLY A H    1 c 
ATOM   4321 H HA2  . GLY A 1 279 ? 38.140  6.383   -9.485  1.000 28.511 0 294  GLY A HA2  1 c 
ATOM   4322 H HA3  . GLY A 1 279 ? 37.665  5.187   -8.546  1.000 28.506 0 294  GLY A HA3  1 c 
ATOM   4323 N N    . ARG A 1 280 ? 35.172  6.774   -9.570  1.000 25.547 0 295  ARG A N    1 ? 
ATOM   4324 C CA   . ARG A 1 280 ? 33.989  6.726   -10.413 1.000 25.030 0 295  ARG A CA   1 ? 
ATOM   4325 C C    . ARG A 1 280 ? 33.979  7.869   -11.428 1.000 24.268 0 295  ARG A C    1 ? 
ATOM   4326 O O    . ARG A 1 280 ? 34.573  8.914   -11.233 1.000 24.468 0 295  ARG A O    1 ? 
ATOM   4327 C CB   . ARG A 1 280 ? 32.763  6.767   -9.510  1.000 21.959 0 295  ARG A CB   1 ? 
ATOM   4328 C CG   . ARG A 1 280 ? 32.533  5.471   -8.740  1.000 21.998 0 295  ARG A CG   1 ? 
ATOM   4329 C CD   . ARG A 1 280 ? 32.300  4.282   -9.617  1.000 23.041 0 295  ARG A CD   1 ? 
ATOM   4330 N NE   . ARG A 1 280 ? 31.861  3.108   -8.865  1.000 22.218 0 295  ARG A NE   1 ? 
ATOM   4331 C CZ   . ARG A 1 280 ? 31.405  1.980   -9.385  1.000 21.978 0 295  ARG A CZ   1 ? 
ATOM   4332 N NH1  . ARG A 1 280 ? 31.418  1.728   -10.668 1.000 23.030 0 295  ARG A NH1  1 ? 
ATOM   4333 N NH2  . ARG A 1 280 ? 30.981  1.042   -8.564  1.000 23.397 0 295  ARG A NH2  1 ? 
ATOM   4334 H H    . ARG A 1 280 ? 35.239  7.417   -8.924  1.000 26.679 0 295  ARG A H    1 c 
ATOM   4335 H HA   . ARG A 1 280 ? 33.995  5.871   -10.904 1.000 24.486 0 295  ARG A HA   1 c 
ATOM   4336 H HB2  . ARG A 1 280 ? 32.865  7.503   -8.870  1.000 22.681 0 295  ARG A HB2  1 c 
ATOM   4337 H HB3  . ARG A 1 280 ? 31.971  6.955   -10.057 1.000 22.658 0 295  ARG A HB3  1 c 
ATOM   4338 H HG2  . ARG A 1 280 ? 33.314  5.296   -8.171  1.000 22.227 0 295  ARG A HG2  1 c 
ATOM   4339 H HG3  . ARG A 1 280 ? 31.757  5.585   -8.149  1.000 22.227 0 295  ARG A HG3  1 c 
ATOM   4340 H HD2  . ARG A 1 280 ? 31.621  4.506   -10.286 1.000 22.592 0 295  ARG A HD2  1 c 
ATOM   4341 H HD3  . ARG A 1 280 ? 33.127  4.063   -10.091 1.000 22.625 0 295  ARG A HD3  1 c 
ATOM   4342 H HE   . ARG A 1 280 ? 31.905  3.151   -7.995  1.000 22.359 0 295  ARG A HE   1 c 
ATOM   4343 H HH11 . ARG A 1 280 ? 30.908  1.082   -10.994 1.000 22.723 0 295  ARG A HH11 1 c 
ATOM   4344 H HH12 . ARG A 1 280 ? 31.937  2.202   -11.208 1.000 22.708 0 295  ARG A HH12 1 c 
ATOM   4345 H HH21 . ARG A 1 280 ? 31.060  0.191   -8.791  1.000 22.950 0 295  ARG A HH21 1 c 
ATOM   4346 H HH22 . ARG A 1 280 ? 30.622  1.264   -7.787  1.000 22.905 0 295  ARG A HH22 1 c 
ATOM   4347 N N    . PRO A 1 281 ? 33.194  7.702   -12.512 1.000 23.282 0 296  PRO A N    1 ? 
ATOM   4348 C CA   . PRO A 1 281 ? 32.932  8.769   -13.461 1.000 25.858 0 296  PRO A CA   1 ? 
ATOM   4349 C C    . PRO A 1 281 ? 32.393  10.011  -12.762 1.000 25.754 0 296  PRO A C    1 ? 
ATOM   4350 O O    . PRO A 1 281 ? 31.635  9.916   -11.778 1.000 24.501 0 296  PRO A O    1 ? 
ATOM   4351 C CB   . PRO A 1 281 ? 31.841  8.141   -14.340 1.000 27.362 0 296  PRO A CB   1 ? 
ATOM   4352 C CG   . PRO A 1 281 ? 32.045  6.673   -14.238 1.000 27.964 0 296  PRO A CG   1 ? 
ATOM   4353 C CD   . PRO A 1 281 ? 32.512  6.450   -12.846 1.000 25.092 0 296  PRO A CD   1 ? 
ATOM   4354 H HA   . PRO A 1 281 ? 33.740  8.976   -13.994 1.000 25.576 0 296  PRO A HA   1 c 
ATOM   4355 H HB2  . PRO A 1 281 ? 30.944  8.390   -14.016 1.000 27.150 0 296  PRO A HB2  1 c 
ATOM   4356 H HB3  . PRO A 1 281 ? 31.931  8.441   -15.274 1.000 27.156 0 296  PRO A HB3  1 c 
ATOM   4357 H HG2  . PRO A 1 281 ? 31.208  6.192   -14.405 1.000 27.141 0 296  PRO A HG2  1 c 
ATOM   4358 H HG3  . PRO A 1 281 ? 32.718  6.369   -14.883 1.000 27.141 0 296  PRO A HG3  1 c 
ATOM   4359 H HD2  . PRO A 1 281 ? 31.756  6.286   -12.243 1.000 25.171 0 296  PRO A HD2  1 c 
ATOM   4360 H HD3  . PRO A 1 281 ? 33.129  5.687   -12.805 1.000 25.267 0 296  PRO A HD3  1 c 
ATOM   4361 N N    . ASP A 1 282 ? 32.679  11.164  -13.375 1.000 24.583 0 297  ASP A N    1 ? 
ATOM   4362 C CA   . ASP A 1 282 ? 32.194  12.423  -12.861 1.000 25.290 0 297  ASP A CA   1 ? 
ATOM   4363 C C    . ASP A 1 282 ? 30.726  12.638  -13.235 1.000 19.473 0 297  ASP A C    1 ? 
ATOM   4364 O O    . ASP A 1 282 ? 30.200  11.960  -14.133 1.000 21.457 0 297  ASP A O    1 ? 
ATOM   4365 C CB   . ASP A 1 282 ? 33.112  13.581  -13.212 1.000 33.061 0 297  ASP A CB   1 ? 
ATOM   4366 C CG   . ASP A 1 282 ? 33.129  14.091  -14.637 1.000 43.939 0 297  ASP A CG   1 ? 
ATOM   4367 O OD1  . ASP A 1 282 ? 33.644  15.224  -14.818 1.000 58.404 0 297  ASP A OD1  1 ? 
ATOM   4368 O OD2  . ASP A 1 282 ? 32.663  13.362  -15.538 1.000 42.426 0 297  ASP A OD2  1 ? 
ATOM   4369 H H    . ASP A 1 282 ? 33.189  11.162  -14.133 1.000 25.073 0 297  ASP A H    1 c 
ATOM   4370 H HA   . ASP A 1 282 ? 32.241  12.370  -11.881 1.000 25.203 0 297  ASP A HA   1 c 
ATOM   4371 H HB2  . ASP A 1 282 ? 32.899  14.340  -12.632 1.000 33.039 0 297  ASP A HB2  1 c 
ATOM   4372 H HB3  . ASP A 1 282 ? 34.026  13.304  -12.997 1.000 33.177 0 297  ASP A HB3  1 c 
ATOM   4373 N N    . PRO A 1 283 ? 30.037  13.529  -12.505 1.000 20.927 0 298  PRO A N    1 ? 
ATOM   4374 C CA   . PRO A 1 283 ? 28.635  13.815  -12.781 1.000 21.035 0 298  PRO A CA   1 ? 
ATOM   4375 C C    . PRO A 1 283 ? 28.392  14.097  -14.252 1.000 19.115 0 298  PRO A C    1 ? 
ATOM   4376 O O    . PRO A 1 283 ? 27.460  13.546  -14.814 1.000 20.310 0 298  PRO A O    1 ? 
ATOM   4377 C CB   . PRO A 1 283 ? 28.365  15.025  -11.930 1.000 20.544 0 298  PRO A CB   1 ? 
ATOM   4378 C CG   . PRO A 1 283 ? 29.246  14.826  -10.709 1.000 20.676 0 298  PRO A CG   1 ? 
ATOM   4379 C CD   . PRO A 1 283 ? 30.515  14.307  -11.347 1.000 21.329 0 298  PRO A CD   1 ? 
ATOM   4380 H HA   . PRO A 1 283 ? 28.075  13.057  -12.479 1.000 20.561 0 298  PRO A HA   1 c 
ATOM   4381 H HB2  . PRO A 1 283 ? 28.608  15.853  -12.407 1.000 20.676 0 298  PRO A HB2  1 c 
ATOM   4382 H HB3  . PRO A 1 283 ? 27.414  15.070  -11.674 1.000 20.683 0 298  PRO A HB3  1 c 
ATOM   4383 H HG2  . PRO A 1 283 ? 29.401  15.671  -10.237 1.000 20.882 0 298  PRO A HG2  1 c 
ATOM   4384 H HG3  . PRO A 1 283 ? 28.861  14.170  -10.091 1.000 20.809 0 298  PRO A HG3  1 c 
ATOM   4385 H HD2  . PRO A 1 283 ? 31.091  15.049  -11.631 1.000 21.206 0 298  PRO A HD2  1 c 
ATOM   4386 H HD3  . PRO A 1 283 ? 31.012  13.739  -10.718 1.000 21.156 0 298  PRO A HD3  1 c 
ATOM   4387 N N    . LEU A 1 284 ? 29.179  14.984  -14.888 1.000 20.861 0 299  LEU A N    1 ? 
ATOM   4388 C CA   . LEU A 1 284 ? 28.949  15.267  -16.304 1.000 20.163 0 299  LEU A CA   1 ? 
ATOM   4389 C C    . LEU A 1 284 ? 28.939  14.017  -17.175 1.000 19.732 0 299  LEU A C    1 ? 
ATOM   4390 O O    . LEU A 1 284 ? 28.089  13.867  -18.053 1.000 20.871 0 299  LEU A O    1 ? 
ATOM   4391 C CB   . LEU A 1 284 ? 29.975  16.277  -16.837 1.000 23.660 0 299  LEU A CB   1 ? 
ATOM   4392 C CG   . LEU A 1 284 ? 29.633  17.737  -16.577 1.000 30.806 0 299  LEU A CG   1 ? 
ATOM   4393 C CD1  . LEU A 1 284 ? 30.790  18.696  -16.879 1.000 31.689 0 299  LEU A CD1  1 ? 
ATOM   4394 C CD2  . LEU A 1 284 ? 28.406  18.115  -17.423 1.000 30.696 0 299  LEU A CD2  1 ? 
ATOM   4395 H H    . LEU A 1 284 ? 29.852  15.414  -14.443 1.000 20.329 0 299  LEU A H    1 c 
ATOM   4396 H HA   . LEU A 1 284 ? 28.052  15.672  -16.374 1.000 20.885 0 299  LEU A HA   1 c 
ATOM   4397 H HB2  . LEU A 1 284 ? 30.847  16.082  -16.422 1.000 24.217 0 299  LEU A HB2  1 c 
ATOM   4398 H HB3  . LEU A 1 284 ? 30.065  16.146  -17.809 1.000 24.248 0 299  LEU A HB3  1 c 
ATOM   4399 H HG   . LEU A 1 284 ? 29.392  17.834  -15.621 1.000 29.414 0 299  LEU A HG   1 c 
ATOM   4400 H HD11 . LEU A 1 284 ? 31.554  18.468  -16.322 1.000 31.428 0 299  LEU A HD11 1 c 
ATOM   4401 H HD12 . LEU A 1 284 ? 30.514  19.609  -16.691 1.000 31.428 0 299  LEU A HD12 1 c 
ATOM   4402 H HD13 . LEU A 1 284 ? 31.039  18.620  -17.815 1.000 31.428 0 299  LEU A HD13 1 c 
ATOM   4403 H HD21 . LEU A 1 284 ? 27.625  17.635  -17.100 1.000 30.527 0 299  LEU A HD21 1 c 
ATOM   4404 H HD22 . LEU A 1 284 ? 28.567  17.882  -18.353 1.000 30.616 0 299  LEU A HD22 1 c 
ATOM   4405 H HD23 . LEU A 1 284 ? 28.247  19.070  -17.353 1.000 30.585 0 299  LEU A HD23 1 c 
ATOM   4406 N N    . THR A 1 285 ? 29.904  13.080  -17.008 1.000 18.867 0 300  THR A N    1 ? 
ATOM   4407 C CA   . THR A 1 285 ? 29.922  11.833  -17.743 1.000 19.003 0 300  THR A CA   1 ? 
ATOM   4408 C C    . THR A 1 285 ? 28.605  11.063  -17.549 1.000 19.340 0 300  THR A C    1 ? 
ATOM   4409 O O    . THR A 1 285 ? 28.047  10.519  -18.503 1.000 19.430 0 300  THR A O    1 ? 
ATOM   4410 C CB   . THR A 1 285 ? 31.085  10.953  -17.309 1.000 23.602 0 300  THR A CB   1 ? 
ATOM   4411 O OG1  . THR A 1 285 ? 32.287  11.659  -17.607 1.000 23.279 0 300  THR A OG1  1 ? 
ATOM   4412 C CG2  . THR A 1 285 ? 31.020  9.632   -18.032 1.000 25.116 0 300  THR A CG2  1 ? 
ATOM   4413 H H    . THR A 1 285 ? 30.573  13.241  -16.407 1.000 19.145 0 300  THR A H    1 c 
ATOM   4414 H HA   . THR A 1 285 ? 30.027  12.040  -18.697 1.000 19.817 0 300  THR A HA   1 c 
ATOM   4415 H HB   . THR A 1 285 ? 31.034  10.791  -16.337 1.000 22.882 0 300  THR A HB   1 c 
ATOM   4416 H HG1  . THR A 1 285 ? 32.327  11.811  -18.457 0.000 23.290 0 300  THR A HG1  1 c 
ATOM   4417 H HG21 . THR A 1 285 ? 31.873  9.173   -17.944 1.000 24.647 0 300  THR A HG21 1 c 
ATOM   4418 H HG22 . THR A 1 285 ? 30.833  9.785   -18.973 1.000 24.646 0 300  THR A HG22 1 c 
ATOM   4419 H HG23 . THR A 1 285 ? 30.317  9.081   -17.647 1.000 24.621 0 300  THR A HG23 1 c 
ATOM   4420 N N    . LEU A 1 286 ? 28.106  11.066  -16.317 1.000 19.230 0 301  LEU A N    1 ? 
ATOM   4421 C CA   . LEU A 1 286 ? 26.889  10.339  -16.012 1.000 18.108 0 301  LEU A CA   1 ? 
ATOM   4422 C C    . LEU A 1 286 ? 25.653  11.024  -16.596 1.000 16.796 0 301  LEU A C    1 ? 
ATOM   4423 O O    . LEU A 1 286 ? 24.806  10.330  -17.142 1.000 18.143 0 301  LEU A O    1 ? 
ATOM   4424 C CB   . LEU A 1 286 ? 26.769  10.152  -14.495 1.000 18.245 0 301  LEU A CB   1 ? 
ATOM   4425 C CG   . LEU A 1 286 ? 27.723  9.124   -13.865 1.000 18.968 0 301  LEU A CG   1 ? 
ATOM   4426 C CD1  . LEU A 1 286 ? 27.787  9.360   -12.382 1.000 19.743 0 301  LEU A CD1  1 ? 
ATOM   4427 C CD2  . LEU A 1 286 ? 27.300  7.723   -14.181 1.000 21.741 0 301  LEU A CD2  1 ? 
ATOM   4428 H H    . LEU A 1 286 ? 28.533  11.522  -15.650 1.000 18.987 0 301  LEU A H    1 c 
ATOM   4429 H HA   . LEU A 1 286 ? 26.962  9.444   -16.432 1.000 18.139 0 301  LEU A HA   1 c 
ATOM   4430 H HB2  . LEU A 1 286 ? 26.925  11.025  -14.065 1.000 18.387 0 301  LEU A HB2  1 c 
ATOM   4431 H HB3  . LEU A 1 286 ? 25.844  9.882   -14.291 1.000 18.357 0 301  LEU A HB3  1 c 
ATOM   4432 H HG   . LEU A 1 286 ? 28.629  9.268   -14.242 1.000 19.472 0 301  LEU A HG   1 c 
ATOM   4433 H HD11 . LEU A 1 286 ? 28.148  10.245  -12.208 1.000 19.501 0 301  LEU A HD11 1 c 
ATOM   4434 H HD12 . LEU A 1 286 ? 28.360  8.691   -11.971 1.000 19.507 0 301  LEU A HD12 1 c 
ATOM   4435 H HD13 . LEU A 1 286 ? 26.894  9.296   -12.004 1.000 19.507 0 301  LEU A HD13 1 c 
ATOM   4436 H HD21 . LEU A 1 286 ? 27.348  7.576   -15.141 1.000 20.849 0 301  LEU A HD21 1 c 
ATOM   4437 H HD22 . LEU A 1 286 ? 26.387  7.583   -13.878 1.000 20.865 0 301  LEU A HD22 1 c 
ATOM   4438 H HD23 . LEU A 1 286 ? 27.890  7.096   -13.730 1.000 20.865 0 301  LEU A HD23 1 c 
ATOM   4439 N N    . TYR A 1 287 ? 25.582  12.341  -16.571 1.000 16.702 0 302  TYR A N    1 ? 
ATOM   4440 C CA   . TYR A 1 287 ? 24.473  13.016  -17.231 1.000 16.511 0 302  TYR A CA   1 ? 
ATOM   4441 C C    . TYR A 1 287 ? 24.464  12.671  -18.725 1.000 17.296 0 302  TYR A C    1 ? 
ATOM   4442 O O    . TYR A 1 287 ? 23.412  12.436  -19.341 1.000 16.946 0 302  TYR A O    1 ? 
ATOM   4443 C CB   . TYR A 1 287 ? 24.506  14.531  -17.071 1.000 17.625 0 302  TYR A CB   1 ? 
ATOM   4444 C CG   . TYR A 1 287 ? 24.321  15.008  -15.650 1.000 16.666 0 302  TYR A CG   1 ? 
ATOM   4445 C CD1  . TYR A 1 287 ? 23.135  14.780  -14.942 1.000 17.109 0 302  TYR A CD1  1 ? 
ATOM   4446 C CD2  . TYR A 1 287 ? 25.322  15.701  -14.991 1.000 17.744 0 302  TYR A CD2  1 ? 
ATOM   4447 C CE1  . TYR A 1 287 ? 22.989  15.209  -13.633 1.000 16.812 0 302  TYR A CE1  1 ? 
ATOM   4448 C CE2  . TYR A 1 287 ? 25.197  16.113  -13.696 1.000 17.293 0 302  TYR A CE2  1 ? 
ATOM   4449 C CZ   . TYR A 1 287 ? 24.034  15.848  -12.981 1.000 17.320 0 302  TYR A CZ   1 ? 
ATOM   4450 O OH   . TYR A 1 287 ? 23.895  16.284  -11.699 1.000 18.524 0 302  TYR A OH   1 ? 
ATOM   4451 H H    . TYR A 1 287 ? 26.219  12.835  -16.140 1.000 16.711 0 302  TYR A H    1 c 
ATOM   4452 H HA   . TYR A 1 287 ? 23.627  12.682  -16.830 1.000 16.897 0 302  TYR A HA   1 c 
ATOM   4453 H HB2  . TYR A 1 287 ? 25.368  14.861  -17.408 1.000 17.149 0 302  TYR A HB2  1 c 
ATOM   4454 H HB3  . TYR A 1 287 ? 23.797  14.920  -17.630 1.000 17.145 0 302  TYR A HB3  1 c 
ATOM   4455 H HD1  . TYR A 1 287 ? 22.428  14.312  -15.358 1.000 16.938 0 302  TYR A HD1  1 c 
ATOM   4456 H HD2  . TYR A 1 287 ? 26.137  15.858  -15.438 1.000 17.408 0 302  TYR A HD2  1 c 
ATOM   4457 H HE1  . TYR A 1 287 ? 22.191  15.026  -13.167 1.000 17.012 0 302  TYR A HE1  1 c 
ATOM   4458 H HE2  . TYR A 1 287 ? 25.910  16.562  -13.276 1.000 17.438 0 302  TYR A HE2  1 c 
ATOM   4459 H HH   . TYR A 1 287 ? 24.130  15.667  -11.153 0.000 18.480 0 302  TYR A HH   1 c 
ATOM   4460 N N    . HIS A 1 288 ? 25.641  12.703  -19.362 1.000 17.596 0 303  HIS A N    1 ? 
ATOM   4461 C CA   . HIS A 1 288 ? 25.734  12.386  -20.784 1.000 17.922 0 303  HIS A CA   1 ? 
ATOM   4462 C C    . HIS A 1 288 ? 25.408  10.917  -21.083 1.000 18.152 0 303  HIS A C    1 ? 
ATOM   4463 O O    . HIS A 1 288 ? 24.834  10.637  -22.132 1.000 18.098 0 303  HIS A O    1 ? 
ATOM   4464 C CB   . HIS A 1 288 ? 27.100  12.870  -21.317 1.000 19.166 0 303  HIS A CB   1 ? 
ATOM   4465 C CG   . HIS A 1 288 ? 27.081  14.352  -21.473 1.000 23.894 0 303  HIS A CG   1 ? 
ATOM   4466 N ND1  . HIS A 1 288 ? 26.469  14.926  -22.569 1.000 29.041 0 303  HIS A ND1  1 ? 
ATOM   4467 C CD2  . HIS A 1 288 ? 27.528  15.369  -20.722 1.000 25.124 0 303  HIS A CD2  1 ? 
ATOM   4468 C CE1  . HIS A 1 288 ? 26.572  16.247  -22.456 1.000 32.476 0 303  HIS A CE1  1 ? 
ATOM   4469 N NE2  . HIS A 1 288 ? 27.253  16.526  -21.365 1.000 23.874 0 303  HIS A NE2  1 ? 
ATOM   4470 H H    . HIS A 1 288 ? 26.399  12.932  -18.906 1.000 17.610 0 303  HIS A H    1 c 
ATOM   4471 H HA   . HIS A 1 288 ? 25.046  12.936  -21.235 1.000 18.140 0 303  HIS A HA   1 c 
ATOM   4472 H HB2  . HIS A 1 288 ? 27.805  12.615  -20.682 1.000 19.862 0 303  HIS A HB2  1 c 
ATOM   4473 H HB3  . HIS A 1 288 ? 27.275  12.451  -22.187 1.000 19.876 0 303  HIS A HB3  1 c 
ATOM   4474 H HD1  . HIS A 1 288 ? 26.061  14.485  -23.213 0.000 29.040 0 303  HIS A HD1  1 c 
ATOM   4475 H HD2  . HIS A 1 288 ? 28.010  15.303  -19.923 1.000 24.546 0 303  HIS A HD2  1 c 
ATOM   4476 H HE1  . HIS A 1 288 ? 26.253  16.873  -23.083 1.000 29.352 0 303  HIS A HE1  1 c 
ATOM   4477 H HE2  . HIS A 1 288 ? 27.452  17.331  -21.080 0.000 23.890 0 303  HIS A HE2  1 c 
ATOM   4478 N N    . LYS A 1 289 ? 25.691  9.970   -20.157 1.000 16.914 0 304  LYS A N    1 ? 
ATOM   4479 C CA   . LYS A 1 289 ? 25.248  8.600   -20.330 1.000 18.679 0 304  LYS A CA   1 ? 
ATOM   4480 C C    . LYS A 1 289 ? 23.717  8.497   -20.265 1.000 15.583 0 304  LYS A C    1 ? 
ATOM   4481 O O    . LYS A 1 289 ? 23.112  7.713   -20.979 1.000 17.810 0 304  LYS A O    1 ? 
ATOM   4482 C CB   . LYS A 1 289 ? 25.911  7.660   -19.310 1.000 21.544 0 304  LYS A CB   1 ? 
ATOM   4483 C CG   . LYS A 1 289 ? 27.406  7.451   -19.552 1.000 26.192 0 304  LYS A CG   1 ? 
ATOM   4484 C CD   . LYS A 1 289 ? 28.015  6.588   -18.443 1.000 31.808 0 304  LYS A CD   1 ? 
ATOM   4485 C CE   . LYS A 1 289 ? 29.453  6.189   -18.641 1.000 39.258 0 304  LYS A CE   1 ? 
ATOM   4486 N NZ   . LYS A 1 289 ? 29.564  5.312   -19.816 1.000 45.768 0 304  LYS A NZ   1 ? 
ATOM   4487 H H    . LYS A 1 289 ? 26.173  10.192  -19.412 1.000 17.614 0 304  LYS A H    1 c 
ATOM   4488 H HA   . LYS A 1 289 ? 25.534  8.303   -21.231 1.000 18.195 0 304  LYS A HA   1 c 
ATOM   4489 H HB2  . LYS A 1 289 ? 25.788  8.028   -18.409 1.000 21.888 0 304  LYS A HB2  1 c 
ATOM   4490 H HB3  . LYS A 1 289 ? 25.464  6.788   -19.342 1.000 22.194 0 304  LYS A HB3  1 c 
ATOM   4491 H HG2  . LYS A 1 289 ? 27.532  7.010   -20.420 1.000 26.344 0 304  LYS A HG2  1 c 
ATOM   4492 H HG3  . LYS A 1 289 ? 27.855  8.323   -19.575 1.000 26.189 0 304  LYS A HG3  1 c 
ATOM   4493 H HD2  . LYS A 1 289 ? 27.941  7.080   -17.596 1.000 31.998 0 304  LYS A HD2  1 c 
ATOM   4494 H HD3  . LYS A 1 289 ? 27.472  5.776   -18.351 1.000 32.183 0 304  LYS A HD3  1 c 
ATOM   4495 H HE2  . LYS A 1 289 ? 29.999  6.984   -18.782 1.000 38.786 0 304  LYS A HE2  1 c 
ATOM   4496 H HE3  . LYS A 1 289 ? 29.787  5.723   -17.856 1.000 38.720 0 304  LYS A HE3  1 c 
ATOM   4497 H HZ1  . LYS A 1 289 ? 29.489  5.800   -20.575 1.000 43.341 0 304  LYS A HZ1  1 c 
ATOM   4498 H HZ2  . LYS A 1 289 ? 28.912  4.682   -19.799 1.000 43.413 0 304  LYS A HZ2  1 c 
ATOM   4499 H HZ3  . LYS A 1 289 ? 30.371  4.901   -19.810 1.000 43.549 0 304  LYS A HZ3  1 c 
ATOM   4500 N N    . GLY A 1 290 ? 23.106  9.297   -19.399 1.000 16.048 0 305  GLY A N    1 ? 
ATOM   4501 C CA   . GLY A 1 290 ? 21.650  9.368   -19.327 1.000 17.718 0 305  GLY A CA   1 ? 
ATOM   4502 C C    . GLY A 1 290 ? 21.037  9.787   -20.655 1.000 15.888 0 305  GLY A C    1 ? 
ATOM   4503 O O    . GLY A 1 290 ? 20.035  9.210   -21.141 1.000 15.424 0 305  GLY A O    1 ? 
ATOM   4504 H H    . GLY A 1 290 ? 23.602  9.811   -18.828 1.000 16.314 0 305  GLY A H    1 c 
ATOM   4505 H HA2  . GLY A 1 290 ? 21.299  8.484   -19.067 1.000 16.890 0 305  GLY A HA2  1 c 
ATOM   4506 H HA3  . GLY A 1 290 ? 21.394  10.014  -18.628 1.000 16.890 0 305  GLY A HA3  1 c 
ATOM   4507 N N    . ILE A 1 291 ? 21.598  10.864  -21.207 1.000 15.790 0 306  ILE A N    1 ? 
ATOM   4508 C CA   . ILE A 1 291 ? 21.164  11.338  -22.507 1.000 16.214 0 306  ILE A CA   1 ? 
ATOM   4509 C C    . ILE A 1 291 ? 21.416  10.276  -23.587 1.000 15.520 0 306  ILE A C    1 ? 
ATOM   4510 O O    . ILE A 1 291 ? 20.562  10.027  -24.412 1.000 15.390 0 306  ILE A O    1 ? 
ATOM   4511 C CB   . ILE A 1 291 ? 21.821  12.687  -22.826 1.000 15.336 0 306  ILE A CB   1 ? 
ATOM   4512 C CG1  . ILE A 1 291 ? 21.266  13.789  -21.905 1.000 15.781 0 306  ILE A CG1  1 ? 
ATOM   4513 C CG2  . ILE A 1 291 ? 21.623  13.041  -24.295 1.000 16.880 0 306  ILE A CG2  1 ? 
ATOM   4514 C CD1  . ILE A 1 291 ? 22.210  14.943  -21.766 1.000 18.178 0 306  ILE A CD1  1 ? 
ATOM   4515 H H    . ILE A 1 291 ? 22.259  11.314  -20.765 1.000 15.916 0 306  ILE A H    1 c 
ATOM   4516 H HA   . ILE A 1 291 ? 20.200  11.488  -22.458 1.000 15.833 0 306  ILE A HA   1 c 
ATOM   4517 H HB   . ILE A 1 291 ? 22.781  12.604  -22.658 1.000 15.880 0 306  ILE A HB   1 c 
ATOM   4518 H HG12 . ILE A 1 291 ? 20.417  14.112  -22.270 1.000 16.208 0 306  ILE A HG12 1 c 
ATOM   4519 H HG13 . ILE A 1 291 ? 21.093  13.411  -21.019 1.000 16.204 0 306  ILE A HG13 1 c 
ATOM   4520 H HG21 . ILE A 1 291 ? 21.841  13.977  -24.436 1.000 16.422 0 306  ILE A HG21 1 c 
ATOM   4521 H HG22 . ILE A 1 291 ? 20.697  12.885  -24.546 1.000 16.408 0 306  ILE A HG22 1 c 
ATOM   4522 H HG23 . ILE A 1 291 ? 22.204  12.490  -24.846 1.000 16.407 0 306  ILE A HG23 1 c 
ATOM   4523 H HD11 . ILE A 1 291 ? 23.062  14.628  -21.410 1.000 17.412 0 306  ILE A HD11 1 c 
ATOM   4524 H HD12 . ILE A 1 291 ? 21.829  15.604  -21.157 1.000 17.421 0 306  ILE A HD12 1 c 
ATOM   4525 H HD13 . ILE A 1 291 ? 22.357  15.355  -22.639 1.000 17.416 0 306  ILE A HD13 1 c 
ATOM   4526 N N    . ALA A 1 292 ? 22.572  9.616   -23.557 1.000 17.359 0 307  ALA A N    1 ? 
ATOM   4527 C CA   . ALA A 1 292 ? 22.879  8.559   -24.520 1.000 19.655 0 307  ALA A CA   1 ? 
ATOM   4528 C C    . ALA A 1 292 ? 21.893  7.393   -24.425 1.000 17.343 0 307  ALA A C    1 ? 
ATOM   4529 O O    . ALA A 1 292 ? 21.460  6.853   -25.444 1.000 17.261 0 307  ALA A O    1 ? 
ATOM   4530 C CB   . ALA A 1 292 ? 24.319  8.080   -24.361 1.000 19.866 0 307  ALA A CB   1 ? 
ATOM   4531 H H    . ALA A 1 292 ? 23.196  9.830   -22.923 1.000 17.375 0 307  ALA A H    1 c 
ATOM   4532 H HA   . ALA A 1 292 ? 22.784  8.953   -25.431 1.000 18.748 0 307  ALA A HA   1 c 
ATOM   4533 H HB1  . ALA A 1 292 ? 24.929  8.822   -24.509 1.000 19.803 0 307  ALA A HB1  1 c 
ATOM   4534 H HB2  . ALA A 1 292 ? 24.451  7.731   -23.464 1.000 19.803 0 307  ALA A HB2  1 c 
ATOM   4535 H HB3  . ALA A 1 292 ? 24.504  7.379   -25.009 1.000 19.803 0 307  ALA A HB3  1 c 
ATOM   4536 N N    . SER A 1 293 ? 21.486  7.044   -23.196 1.000 16.319 0 308  SER A N    1 ? 
ATOM   4537 C CA   . SER A 1 293 ? 20.482  5.991   -22.990 1.000 16.417 0 308  SER A CA   1 ? 
ATOM   4538 C C    . SER A 1 293 ? 19.163  6.370   -23.660 1.000 16.797 0 308  SER A C    1 ? 
ATOM   4539 O O    . SER A 1 293 ? 18.521  5.565   -24.372 1.000 15.838 0 308  SER A O    1 ? 
ATOM   4540 C CB   . SER A 1 293 ? 20.292  5.708   -21.503 1.000 17.547 0 308  SER A CB   1 ? 
ATOM   4541 O OG   . SER A 1 293 ? 19.220  4.761   -21.347 1.000 17.327 0 308  SER A OG   1 ? 
ATOM   4542 H H    . SER A 1 293 ? 21.841  7.464   -22.466 1.000 16.611 0 308  SER A H    1 c 
ATOM   4543 H HA   . SER A 1 293 ? 20.817  5.164   -23.421 1.000 16.672 0 308  SER A HA   1 c 
ATOM   4544 H HB2  . SER A 1 293 ? 21.115  5.341   -21.130 1.000 17.234 0 308  SER A HB2  1 c 
ATOM   4545 H HB3  . SER A 1 293 ? 20.073  6.535   -21.035 1.000 17.226 0 308  SER A HB3  1 c 
ATOM   4546 H HG   . SER A 1 293 ? 19.115  4.605   -20.521 0.000 17.300 0 308  SER A HG   1 c 
ATOM   4547 N N    . ALA A 1 294 ? 18.741  7.635   -23.479 1.000 14.862 0 309  ALA A N    1 ? 
ATOM   4548 C CA   . ALA A 1 294 ? 17.513  8.091   -24.105 1.000 15.239 0 309  ALA A CA   1 ? 
ATOM   4549 C C    . ALA A 1 294 ? 17.593  8.074   -25.642 1.000 15.848 0 309  ALA A C    1 ? 
ATOM   4550 O O    . ALA A 1 294 ? 16.637  7.724   -26.330 1.000 16.055 0 309  ALA A O    1 ? 
ATOM   4551 C CB   . ALA A 1 294 ? 17.155  9.466   -23.585 1.000 16.910 0 309  ALA A CB   1 ? 
ATOM   4552 H H    . ALA A 1 294 ? 19.221  8.212   -22.957 1.000 15.412 0 309  ALA A H    1 c 
ATOM   4553 H HA   . ALA A 1 294 ? 16.790  7.462   -23.838 1.000 15.571 0 309  ALA A HA   1 c 
ATOM   4554 H HB1  . ALA A 1 294 ? 17.056  9.434   -22.619 1.000 16.397 0 309  ALA A HB1  1 c 
ATOM   4555 H HB2  . ALA A 1 294 ? 17.859  10.096  -23.815 1.000 16.397 0 309  ALA A HB2  1 c 
ATOM   4556 H HB3  . ALA A 1 294 ? 16.319  9.758   -23.985 1.000 16.397 0 309  ALA A HB3  1 c 
ATOM   4557 N N    . LYS A 1 295 ? 18.741  8.484   -26.196 1.000 17.588 0 310  LYS A N    1 ? 
ATOM   4558 C CA   . LYS A 1 295 ? 18.902  8.467   -27.647 1.000 16.822 0 310  LYS A CA   1 ? 
ATOM   4559 C C    . LYS A 1 295 ? 18.899  7.033   -28.192 1.000 17.094 0 310  LYS A C    1 ? 
ATOM   4560 O O    . LYS A 1 295 ? 18.297  6.773   -29.245 1.000 19.297 0 310  LYS A O    1 ? 
ATOM   4561 C CB   . LYS A 1 295 ? 20.221  9.150   -27.995 1.000 18.240 0 310  LYS A CB   1 ? 
ATOM   4562 C CG   . LYS A 1 295 ? 20.175  10.676  -27.847 1.000 19.982 0 310  LYS A CG   1 ? 
ATOM   4563 C CD   . LYS A 1 295 ? 21.529  11.308  -28.137 1.000 21.470 0 310  LYS A CD   1 ? 
ATOM   4564 C CE   . LYS A 1 295 ? 21.569  12.776  -27.951 1.000 22.527 0 310  LYS A CE   1 ? 
ATOM   4565 N NZ   . LYS A 1 295 ? 20.921  13.506  -29.037 1.000 26.041 0 310  LYS A NZ   1 ? 
ATOM   4566 H H    . LYS A 1 295 ? 19.427  8.783   -25.670 1.000 16.978 0 310  LYS A H    1 c 
ATOM   4567 H HA   . LYS A 1 295 ? 18.153  8.970   -28.055 1.000 17.257 0 310  LYS A HA   1 c 
ATOM   4568 H HB2  . LYS A 1 295 ? 20.928  8.798   -27.414 1.000 18.271 0 310  LYS A HB2  1 c 
ATOM   4569 H HB3  . LYS A 1 295 ? 20.458  8.932   -28.922 1.000 18.273 0 310  LYS A HB3  1 c 
ATOM   4570 H HG2  . LYS A 1 295 ? 19.509  11.035  -28.471 1.000 19.930 0 310  LYS A HG2  1 c 
ATOM   4571 H HG3  . LYS A 1 295 ? 19.898  10.901  -26.932 1.000 19.903 0 310  LYS A HG3  1 c 
ATOM   4572 H HD2  . LYS A 1 295 ? 22.199  10.896  -27.549 1.000 21.367 0 310  LYS A HD2  1 c 
ATOM   4573 H HD3  . LYS A 1 295 ? 21.780  11.099  -29.063 1.000 21.383 0 310  LYS A HD3  1 c 
ATOM   4574 H HE2  . LYS A 1 295 ? 21.131  13.003  -27.113 1.000 22.990 0 310  LYS A HE2  1 c 
ATOM   4575 H HE3  . LYS A 1 295 ? 22.497  13.065  -27.890 1.000 23.043 0 310  LYS A HE3  1 c 
ATOM   4576 H HZ1  . LYS A 1 295 ? 20.049  13.267  -29.091 1.000 24.816 0 310  LYS A HZ1  1 c 
ATOM   4577 H HZ2  . LYS A 1 295 ? 21.331  13.315  -29.822 1.000 24.859 0 310  LYS A HZ2  1 c 
ATOM   4578 H HZ3  . LYS A 1 295 ? 20.976  14.397  -28.882 1.000 24.878 0 310  LYS A HZ3  1 c 
ATOM   4579 N N    . THR A 1 296 ? 19.502  6.112   -27.433 1.000 16.995 0 311  THR A N    1 ? 
ATOM   4580 C CA   . THR A 1 296 ? 19.714  4.750   -27.921 1.000 17.810 0 311  THR A CA   1 ? 
ATOM   4581 C C    . THR A 1 296 ? 18.437  3.927   -27.874 1.000 16.934 0 311  THR A C    1 ? 
ATOM   4582 O O    . THR A 1 296 ? 18.075  3.233   -28.825 1.000 19.165 0 311  THR A O    1 ? 
ATOM   4583 C CB   . THR A 1 296 ? 20.814  4.088   -27.113 1.000 18.312 0 311  THR A CB   1 ? 
ATOM   4584 O OG1  . THR A 1 296 ? 22.019  4.760   -27.470 1.000 21.847 0 311  THR A OG1  1 ? 
ATOM   4585 C CG2  . THR A 1 296 ? 20.833  2.609   -27.364 1.000 17.804 0 311  THR A CG2  1 ? 
ATOM   4586 H H    . THR A 1 296 ? 19.792  6.332   -26.595 1.000 17.218 0 311  THR A H    1 c 
ATOM   4587 H HA   . THR A 1 296 ? 20.012  4.805   -28.856 1.000 17.604 0 311  THR A HA   1 c 
ATOM   4588 H HB   . THR A 1 296 ? 20.640  4.233   -26.152 1.000 18.746 0 311  THR A HB   1 c 
ATOM   4589 H HG1  . THR A 1 296 ? 22.159  4.672   -28.319 0.000 21.780 0 311  THR A HG1  1 c 
ATOM   4590 H HG21 . THR A 1 296 ? 21.679  2.240   -27.058 1.000 17.953 0 311  THR A HG21 1 c 
ATOM   4591 H HG22 . THR A 1 296 ? 20.734  2.439   -28.315 1.000 17.948 0 311  THR A HG22 1 c 
ATOM   4592 H HG23 . THR A 1 296 ? 20.104  2.185   -26.881 1.000 17.952 0 311  THR A HG23 1 c 
ATOM   4593 N N    . TYR A 1 297 ? 17.738  4.006   -26.732 1.000 16.436 0 312  TYR A N    1 ? 
ATOM   4594 C CA   . TYR A 1 297 ? 16.614  3.148   -26.448 1.000 16.464 0 312  TYR A CA   1 ? 
ATOM   4595 C C    . TYR A 1 297 ? 15.243  3.789   -26.629 1.000 17.402 0 312  TYR A C    1 ? 
ATOM   4596 O O    . TYR A 1 297 ? 14.269  3.042   -26.800 1.000 18.376 0 312  TYR A O    1 ? 
ATOM   4597 C CB   . TYR A 1 297 ? 16.694  2.582   -25.024 1.000 15.743 0 312  TYR A CB   1 ? 
ATOM   4598 C CG   . TYR A 1 297 ? 17.891  1.662   -24.848 1.000 16.537 0 312  TYR A CG   1 ? 
ATOM   4599 C CD1  . TYR A 1 297 ? 17.916  0.411   -25.436 1.000 17.925 0 312  TYR A CD1  1 ? 
ATOM   4600 C CD2  . TYR A 1 297 ? 19.019  2.114   -24.183 1.000 16.996 0 312  TYR A CD2  1 ? 
ATOM   4601 C CE1  . TYR A 1 297 ? 19.047  -0.380  -25.323 1.000 19.328 0 312  TYR A CE1  1 ? 
ATOM   4602 C CE2  . TYR A 1 297 ? 20.190  1.368   -24.153 1.000 19.084 0 312  TYR A CE2  1 ? 
ATOM   4603 C CZ   . TYR A 1 297 ? 20.167  0.087   -24.671 1.000 18.550 0 312  TYR A CZ   1 ? 
ATOM   4604 O OH   . TYR A 1 297 ? 21.278  -0.730  -24.606 1.000 21.620 0 312  TYR A OH   1 ? 
ATOM   4605 H H    . TYR A 1 297 ? 17.985  4.622   -26.103 1.000 16.567 0 312  TYR A H    1 c 
ATOM   4606 H HA   . TYR A 1 297 ? 16.664  2.377   -27.073 1.000 16.515 0 312  TYR A HA   1 c 
ATOM   4607 H HB2  . TYR A 1 297 ? 16.760  3.328   -24.388 1.000 16.099 0 312  TYR A HB2  1 c 
ATOM   4608 H HB3  . TYR A 1 297 ? 15.870  2.080   -24.834 1.000 16.103 0 312  TYR A HB3  1 c 
ATOM   4609 H HD1  . TYR A 1 297 ? 17.153  0.084   -25.886 1.000 17.905 0 312  TYR A HD1  1 c 
ATOM   4610 H HD2  . TYR A 1 297 ? 19.031  2.996   -23.847 1.000 17.354 0 312  TYR A HD2  1 c 
ATOM   4611 H HE1  . TYR A 1 297 ? 19.057  -1.240  -25.707 1.000 18.797 0 312  TYR A HE1  1 c 
ATOM   4612 H HE2  . TYR A 1 297 ? 20.938  1.671   -23.668 1.000 18.456 0 312  TYR A HE2  1 c 
ATOM   4613 H HH   . TYR A 1 297 ? 21.787  -0.585  -25.283 0.000 21.640 0 312  TYR A HH   1 c 
ATOM   4614 N N    . TYR A 1 298 ? 15.148  5.129   -26.592 1.000 15.859 0 313  TYR A N    1 ? 
ATOM   4615 C CA   . TYR A 1 298 ? 13.874  5.799   -26.538 1.000 15.367 0 313  TYR A CA   1 ? 
ATOM   4616 C C    . TYR A 1 298 ? 13.737  6.911   -27.589 1.000 16.495 0 313  TYR A C    1 ? 
ATOM   4617 O O    . TYR A 1 298 ? 12.937  7.833   -27.385 1.000 16.685 0 313  TYR A O    1 ? 
ATOM   4618 C CB   . TYR A 1 298 ? 13.619  6.353   -25.124 1.000 14.473 0 313  TYR A CB   1 ? 
ATOM   4619 C CG   . TYR A 1 298 ? 13.680  5.273   -24.047 1.000 14.515 0 313  TYR A CG   1 ? 
ATOM   4620 C CD1  . TYR A 1 298 ? 12.731  4.262   -23.994 1.000 14.910 0 313  TYR A CD1  1 ? 
ATOM   4621 C CD2  . TYR A 1 298 ? 14.756  5.191   -23.173 1.000 14.491 0 313  TYR A CD2  1 ? 
ATOM   4622 C CE1  . TYR A 1 298 ? 12.814  3.265   -23.050 1.000 14.545 0 313  TYR A CE1  1 ? 
ATOM   4623 C CE2  . TYR A 1 298 ? 14.867  4.173   -22.231 1.000 15.087 0 313  TYR A CE2  1 ? 
ATOM   4624 C CZ   . TYR A 1 298 ? 13.901  3.194   -22.195 1.000 14.664 0 313  TYR A CZ   1 ? 
ATOM   4625 O OH   . TYR A 1 298 ? 13.919  2.151   -21.298 1.000 15.530 0 313  TYR A OH   1 ? 
ATOM   4626 H H    . TYR A 1 298 ? 15.910  5.634   -26.591 1.000 16.118 0 313  TYR A H    1 c 
ATOM   4627 H HA   . TYR A 1 298 ? 13.169  5.124   -26.726 1.000 15.519 0 313  TYR A HA   1 c 
ATOM   4628 H HB2  . TYR A 1 298 ? 14.293  7.042   -24.928 1.000 14.681 0 313  TYR A HB2  1 c 
ATOM   4629 H HB3  . TYR A 1 298 ? 12.731  6.775   -25.104 1.000 14.695 0 313  TYR A HB3  1 c 
ATOM   4630 H HD1  . TYR A 1 298 ? 11.995  4.283   -24.585 1.000 14.732 0 313  TYR A HD1  1 c 
ATOM   4631 H HD2  . TYR A 1 298 ? 15.432  5.847   -23.216 1.000 14.645 0 313  TYR A HD2  1 c 
ATOM   4632 H HE1  . TYR A 1 298 ? 12.157  2.590   -23.024 1.000 14.664 0 313  TYR A HE1  1 c 
ATOM   4633 H HE2  . TYR A 1 298 ? 15.600  4.144   -21.642 1.000 14.852 0 313  TYR A HE2  1 c 
ATOM   4634 H HH   . TYR A 1 298 ? 14.317  1.473   -21.641 0.000 15.530 0 313  TYR A HH   1 c 
ATOM   4635 N N    A ARG A 1 299 ? 14.473  6.771   -28.706 0.500 16.584 0 314  ARG A N    1 ? 
ATOM   4636 N N    B ARG A 1 299 ? 14.502  6.788   -28.691 0.500 17.050 0 314  ARG A N    1 ? 
ATOM   4637 C CA   A ARG A 1 299 ? 14.345  7.651   -29.865 0.500 17.383 0 314  ARG A CA   1 ? 
ATOM   4638 C CA   B ARG A 1 299 ? 14.382  7.655   -29.862 0.500 18.323 0 314  ARG A CA   1 ? 
ATOM   4639 C C    A ARG A 1 299 ? 14.570  9.124   -29.492 0.500 18.256 0 314  ARG A C    1 ? 
ATOM   4640 C C    B ARG A 1 299 ? 14.610  9.129   -29.511 0.500 18.770 0 314  ARG A C    1 ? 
ATOM   4641 O O    A ARG A 1 299 ? 14.066  10.016  -30.189 0.500 17.513 0 314  ARG A O    1 ? 
ATOM   4642 O O    B ARG A 1 299 ? 14.154  10.018  -30.238 0.500 17.863 0 314  ARG A O    1 ? 
ATOM   4643 C CB   A ARG A 1 299 ? 12.973  7.461   -30.540 0.500 18.054 0 314  ARG A CB   1 ? 
ATOM   4644 C CB   B ARG A 1 299 ? 13.011  7.457   -30.530 0.500 19.905 0 314  ARG A CB   1 ? 
ATOM   4645 C CG   A ARG A 1 299 ? 12.593  6.064   -31.015 0.500 19.828 0 314  ARG A CG   1 ? 
ATOM   4646 C CG   B ARG A 1 299 ? 12.781  6.045   -31.046 0.500 22.942 0 314  ARG A CG   1 ? 
ATOM   4647 C CD   A ARG A 1 299 ? 11.394  6.051   -31.958 0.500 22.150 0 314  ARG A CD   1 ? 
ATOM   4648 C CD   B ARG A 1 299 ? 11.472  5.805   -31.768 0.500 25.534 0 314  ARG A CD   1 ? 
ATOM   4649 N NE   A ARG A 1 299 ? 10.292  6.757   -31.301 0.500 23.354 0 314  ARG A NE   1 ? 
ATOM   4650 N NE   B ARG A 1 299 ? 11.510  4.463   -32.354 0.500 28.988 0 314  ARG A NE   1 ? 
ATOM   4651 C CZ   A ARG A 1 299 ? 9.028   6.917   -31.694 0.500 26.100 0 314  ARG A CZ   1 ? 
ATOM   4652 C CZ   B ARG A 1 299 ? 10.572  3.894   -33.107 0.500 35.792 0 314  ARG A CZ   1 ? 
ATOM   4653 N NH1  A ARG A 1 299 ? 8.702   6.649   -32.966 0.500 25.352 0 314  ARG A NH1  1 ? 
ATOM   4654 N NH1  B ARG A 1 299 ? 9.486   4.567   -33.439 0.500 37.912 0 314  ARG A NH1  1 ? 
ATOM   4655 N NH2  A ARG A 1 299 ? 8.148   7.319   -30.749 0.500 21.878 0 314  ARG A NH2  1 ? 
ATOM   4656 N NH2  B ARG A 1 299 ? 10.741  2.644   -33.513 0.500 36.276 0 314  ARG A NH2  1 ? 
ATOM   4657 H H    A ARG A 1 299 ? 15.081  6.091   -28.749 0.500 16.719 0 314  ARG A H    1 c 
ATOM   4658 H H    B ARG A 1 299 ? 15.128  6.123   -28.715 0.500 17.161 0 314  ARG A H    1 c 
ATOM   4659 H HA   A ARG A 1 299 ? 15.042  7.392   -30.520 0.500 17.499 0 314  ARG A HA   1 c 
ATOM   4660 H HA   B ARG A 1 299 ? 15.079  7.383   -30.512 0.500 18.424 0 314  ARG A HA   1 c 
ATOM   4661 H HB2  A ARG A 1 299 ? 12.284  7.764   -29.911 0.500 18.272 0 314  ARG A HB2  1 c 
ATOM   4662 H HB2  B ARG A 1 299 ? 12.306  7.677   -29.886 0.500 20.144 0 314  ARG A HB2  1 c 
ATOM   4663 H HB3  A ARG A 1 299 ? 12.938  8.062   -31.314 0.500 18.286 0 314  ARG A HB3  1 c 
ATOM   4664 H HB3  B ARG A 1 299 ? 12.934  8.083   -31.282 0.500 20.176 0 314  ARG A HB3  1 c 
ATOM   4665 H HG2  A ARG A 1 299 ? 13.362  5.662   -31.474 0.500 19.906 0 314  ARG A HG2  1 c 
ATOM   4666 H HG2  B ARG A 1 299 ? 13.516  5.813   -31.654 0.500 22.762 0 314  ARG A HG2  1 c 
ATOM   4667 H HG3  A ARG A 1 299 ? 12.387  5.505   -30.234 0.500 19.906 0 314  ARG A HG3  1 c 
ATOM   4668 H HG3  B ARG A 1 299 ? 12.835  5.424   -30.287 0.500 22.763 0 314  ARG A HG3  1 c 
ATOM   4669 H HD2  A ARG A 1 299 ? 11.618  6.499   -32.799 0.500 21.882 0 314  ARG A HD2  1 c 
ATOM   4670 H HD2  B ARG A 1 299 ? 10.722  5.871   -31.142 0.500 25.686 0 314  ARG A HD2  1 c 
ATOM   4671 H HD3  A ARG A 1 299 ? 11.126  5.130   -32.153 0.500 21.882 0 314  ARG A HD3  1 c 
ATOM   4672 H HD3  B ARG A 1 299 ? 11.349  6.470   -32.476 0.500 25.685 0 314  ARG A HD3  1 c 
ATOM   4673 H HE   A ARG A 1 299 ? 10.483  7.132   -30.539 0.500 23.678 0 314  ARG A HE   1 c 
ATOM   4674 H HE   B ARG A 1 299 ? 12.219  3.982   -32.195 0.500 29.587 0 314  ARG A HE   1 c 
ATOM   4675 H HH11 A ARG A 1 299 ? 7.876   6.791   -33.246 0.500 25.580 0 314  ARG A HH11 1 c 
ATOM   4676 H HH11 B ARG A 1 299 ? 8.873   4.186   -33.950 0.500 37.246 0 314  ARG A HH11 1 c 
ATOM   4677 H HH12 A ARG A 1 299 ? 9.314   6.332   -33.518 0.500 25.580 0 314  ARG A HH12 1 c 
ATOM   4678 H HH12 B ARG A 1 299 ? 9.376   5.394   -33.149 0.500 37.246 0 314  ARG A HH12 1 c 
ATOM   4679 H HH21 A ARG A 1 299 ? 7.301   7.451   -30.967 0.500 23.100 0 314  ARG A HH21 1 c 
ATOM   4680 H HH21 B ARG A 1 299 ? 10.056  2.194   -33.845 0.500 36.127 0 314  ARG A HH21 1 c 
ATOM   4681 H HH22 A ARG A 1 299 ? 8.422   7.448   -29.919 0.500 23.100 0 314  ARG A HH22 1 c 
ATOM   4682 H HH22 B ARG A 1 299 ? 11.537  2.265   -33.449 0.500 36.127 0 314  ARG A HH22 1 c 
ATOM   4683 N N    . ASP A 1 300 ? 15.334  9.394   -28.414 1.000 16.899 0 315  ASP A N    1 ? 
ATOM   4684 C CA   . ASP A 1 300 ? 15.568  10.748  -27.939 1.000 17.136 0 315  ASP A CA   1 ? 
ATOM   4685 C C    . ASP A 1 300 ? 14.260  11.502  -27.728 1.000 15.975 0 315  ASP A C    1 ? 
ATOM   4686 O O    . ASP A 1 300 ? 14.180  12.714  -28.011 1.000 17.727 0 315  ASP A O    1 ? 
ATOM   4687 C CB   . ASP A 1 300 ? 16.461  11.509  -28.912 1.000 17.541 0 315  ASP A CB   1 ? 
ATOM   4688 C CG   . ASP A 1 300 ? 17.311  12.626  -28.356 1.000 20.872 0 315  ASP A CG   1 ? 
ATOM   4689 O OD1  . ASP A 1 300 ? 17.319  12.814  -27.108 1.000 19.459 0 315  ASP A OD1  1 ? 
ATOM   4690 O OD2  . ASP A 1 300 ? 17.973  13.300  -29.193 1.000 20.485 0 315  ASP A OD2  1 ? 
ATOM   4691 H H    . ASP A 1 300 ? 15.722  8.704   -27.957 1.000 17.536 0 315  ASP A H    1 c 
ATOM   4692 H HA   . ASP A 1 300 ? 16.037  10.689  -27.077 1.000 16.973 0 315  ASP A HA   1 c 
ATOM   4693 H HB2  . ASP A 1 300 ? 17.070  10.863  -29.326 1.000 18.159 0 315  ASP A HB2  1 c 
ATOM   4694 H HB3  . ASP A 1 300 ? 15.909  11.886  -29.628 1.000 18.149 0 315  ASP A HB3  1 c 
ATOM   4695 N N    . GLU A 1 301 ? 13.270  10.844  -27.123 1.000 15.435 0 316  GLU A N    1 ? 
ATOM   4696 C CA   . GLU A 1 301 ? 11.961  11.418  -26.896 1.000 16.085 0 316  GLU A CA   1 ? 
ATOM   4697 C C    . GLU A 1 301 ? 11.712  11.804  -25.436 1.000 15.034 0 316  GLU A C    1 ? 
ATOM   4698 O O    . GLU A 1 301 ? 10.584  12.101  -25.042 1.000 14.888 0 316  GLU A O    1 ? 
ATOM   4699 C CB   . GLU A 1 301 ? 10.859  10.469  -27.363 1.000 18.933 0 316  GLU A CB   1 ? 
ATOM   4700 C CG   . GLU A 1 301 ? 10.918  10.186  -28.854 1.000 23.343 0 316  GLU A CG   1 ? 
ATOM   4701 C CD   . GLU A 1 301 ? 10.422  11.266  -29.749 1.000 33.043 0 316  GLU A CD   1 ? 
ATOM   4702 O OE1  . GLU A 1 301 ? 10.357  10.943  -30.960 1.000 40.591 0 316  GLU A OE1  1 ? 
ATOM   4703 O OE2  . GLU A 1 301 ? 10.001  12.336  -29.261 1.000 30.638 0 316  GLU A OE2  1 ? 
ATOM   4704 H H    . GLU A 1 301 ? 13.424  9.992   -26.832 1.000 15.725 0 316  GLU A H    1 c 
ATOM   4705 H HA   . GLU A 1 301 ? 11.890  12.242  -27.440 1.000 16.358 0 316  GLU A HA   1 c 
ATOM   4706 H HB2  . GLU A 1 301 ? 10.940  9.625   -26.872 1.000 19.137 0 316  GLU A HB2  1 c 
ATOM   4707 H HB3  . GLU A 1 301 ? 9.988   10.858  -27.147 1.000 19.127 0 316  GLU A HB3  1 c 
ATOM   4708 H HG2  . GLU A 1 301 ? 11.843  9.988   -29.098 1.000 23.969 0 316  GLU A HG2  1 c 
ATOM   4709 H HG3  . GLU A 1 301 ? 10.396  9.376   -29.037 1.000 24.128 0 316  GLU A HG3  1 c 
ATOM   4710 N N    . HIS A 1 302 ? 12.757  11.765  -24.600 1.000 15.006 0 317  HIS A N    1 ? 
ATOM   4711 C CA   . HIS A 1 302 ? 12.636  12.081  -23.181 1.000 14.971 0 317  HIS A CA   1 ? 
ATOM   4712 C C    . HIS A 1 302 ? 13.159  13.473  -22.854 1.000 15.381 0 317  HIS A C    1 ? 
ATOM   4713 O O    . HIS A 1 302 ? 14.196  13.918  -23.432 1.000 14.780 0 317  HIS A O    1 ? 
ATOM   4714 C CB   . HIS A 1 302 ? 13.413  11.042  -22.350 1.000 15.269 0 317  HIS A CB   1 ? 
ATOM   4715 C CG   . HIS A 1 302 ? 12.868  9.663   -22.401 1.000 14.142 0 317  HIS A CG   1 ? 
ATOM   4716 N ND1  . HIS A 1 302 ? 13.347  8.689   -21.544 1.000 16.036 0 317  HIS A ND1  1 ? 
ATOM   4717 C CD2  . HIS A 1 302 ? 11.913  9.085   -23.156 1.000 14.979 0 317  HIS A CD2  1 ? 
ATOM   4718 C CE1  . HIS A 1 302 ? 12.657  7.560   -21.763 1.000 15.217 0 317  HIS A CE1  1 ? 
ATOM   4719 N NE2  . HIS A 1 302 ? 11.749  7.765   -22.749 1.000 15.562 0 317  HIS A NE2  1 ? 
ATOM   4720 H H    . HIS A 1 302 ? 13.580  11.535  -24.924 1.000 15.020 0 317  HIS A H    1 c 
ATOM   4721 H HA   . HIS A 1 302 ? 11.682  12.038  -22.927 1.000 15.094 0 317  HIS A HA   1 c 
ATOM   4722 H HB2  . HIS A 1 302 ? 14.343  11.025  -22.666 1.000 14.931 0 317  HIS A HB2  1 c 
ATOM   4723 H HB3  . HIS A 1 302 ? 13.432  11.340  -21.416 1.000 14.935 0 317  HIS A HB3  1 c 
ATOM   4724 H HD1  . HIS A 1 302 ? 13.977  8.804   -20.940 0.000 16.040 0 317  HIS A HD1  1 c 
ATOM   4725 H HD2  . HIS A 1 302 ? 11.399  9.510   -23.814 1.000 14.919 0 317  HIS A HD2  1 c 
ATOM   4726 H HE1  . HIS A 1 302 ? 12.801  6.746   -21.311 1.000 15.472 0 317  HIS A HE1  1 c 
ATOM   4727 H HE2  . HIS A 1 302 ? 11.190  7.163   -23.058 0.000 15.570 0 317  HIS A HE2  1 c 
ATOM   4728 N N    . ILE A 1 303 ? 12.497  14.134  -21.879 1.000 14.084 0 318  ILE A N    1 ? 
ATOM   4729 C CA   . ILE A 1 303 ? 12.879  15.500  -21.512 1.000 14.624 0 318  ILE A CA   1 ? 
ATOM   4730 C C    . ILE A 1 303 ? 13.843  15.574  -20.332 1.000 14.228 0 318  ILE A C    1 ? 
ATOM   4731 O O    . ILE A 1 303 ? 14.795  16.374  -20.328 1.000 15.045 0 318  ILE A O    1 ? 
ATOM   4732 C CB   . ILE A 1 303 ? 11.623  16.337  -21.203 1.000 16.670 0 318  ILE A CB   1 ? 
ATOM   4733 C CG1  . ILE A 1 303 ? 10.652  16.304  -22.328 1.000 20.000 0 318  ILE A CG1  1 ? 
ATOM   4734 C CG2  . ILE A 1 303 ? 11.993  17.767  -20.776 1.000 19.109 0 318  ILE A CG2  1 ? 
ATOM   4735 C CD1  . ILE A 1 303 ? 11.117  17.125  -23.485 1.000 22.485 0 318  ILE A CD1  1 ? 
ATOM   4736 H H    . ILE A 1 303 ? 11.796  13.737  -21.449 1.000 14.545 0 318  ILE A H    1 c 
ATOM   4737 H HA   . ILE A 1 303 ? 13.322  15.903  -22.282 1.000 14.869 0 318  ILE A HA   1 c 
ATOM   4738 H HB   . ILE A 1 303 ? 11.184  15.915  -20.438 1.000 17.286 0 318  ILE A HB   1 c 
ATOM   4739 H HG12 . ILE A 1 303 ? 10.524  15.378  -22.620 1.000 19.619 0 318  ILE A HG12 1 c 
ATOM   4740 H HG13 . ILE A 1 303 ? 9.789   16.647  -22.017 1.000 19.681 0 318  ILE A HG13 1 c 
ATOM   4741 H HG21 . ILE A 1 303 ? 11.224  18.351  -20.891 1.000 18.400 0 318  ILE A HG21 1 c 
ATOM   4742 H HG22 . ILE A 1 303 ? 12.728  18.092  -21.323 1.000 18.357 0 318  ILE A HG22 1 c 
ATOM   4743 H HG23 . ILE A 1 303 ? 12.261  17.771  -19.841 1.000 18.346 0 318  ILE A HG23 1 c 
ATOM   4744 H HD11 . ILE A 1 303 ? 11.105  18.072  -23.248 1.000 21.628 0 318  ILE A HD11 1 c 
ATOM   4745 H HD12 . ILE A 1 303 ? 10.519  16.976  -24.242 1.000 21.630 0 318  ILE A HD12 1 c 
ATOM   4746 H HD13 . ILE A 1 303 ? 12.022  16.866  -23.735 1.000 21.541 0 318  ILE A HD13 1 c 
ATOM   4747 N N    . TYR A 1 304 ? 13.612  14.753  -19.313 1.000 14.098 0 319  TYR A N    1 ? 
ATOM   4748 C CA   . TYR A 1 304 ? 14.339  14.907  -18.083 1.000 14.280 0 319  TYR A CA   1 ? 
ATOM   4749 C C    . TYR A 1 304 ? 15.844  14.652  -18.246 1.000 14.868 0 319  TYR A C    1 ? 
ATOM   4750 O O    . TYR A 1 304 ? 16.580  15.286  -17.491 1.000 14.842 0 319  TYR A O    1 ? 
ATOM   4751 C CB   . TYR A 1 304 ? 13.778  14.139  -16.888 1.000 14.291 0 319  TYR A CB   1 ? 
ATOM   4752 C CG   . TYR A 1 304 ? 12.603  14.860  -16.263 1.000 14.364 0 319  TYR A CG   1 ? 
ATOM   4753 C CD1  . TYR A 1 304 ? 12.798  15.997  -15.513 1.000 16.086 0 319  TYR A CD1  1 ? 
ATOM   4754 C CD2  . TYR A 1 304 ? 11.318  14.341  -16.317 1.000 17.171 0 319  TYR A CD2  1 ? 
ATOM   4755 C CE1  . TYR A 1 304 ? 11.726  16.679  -14.958 1.000 17.921 0 319  TYR A CE1  1 ? 
ATOM   4756 C CE2  . TYR A 1 304 ? 10.246  14.986  -15.705 1.000 17.438 0 319  TYR A CE2  1 ? 
ATOM   4757 C CZ   . TYR A 1 304 ? 10.457  16.162  -15.024 1.000 18.538 0 319  TYR A CZ   1 ? 
ATOM   4758 O OH   . TYR A 1 304 ? 9.393   16.801  -14.429 1.000 20.187 0 319  TYR A OH   1 ? 
ATOM   4759 H H    . TYR A 1 304 ? 12.991  14.088  -19.386 1.000 14.173 0 319  TYR A H    1 c 
ATOM   4760 H HA   . TYR A 1 304 ? 14.255  15.869  -17.846 1.000 14.371 0 319  TYR A HA   1 c 
ATOM   4761 H HB2  . TYR A 1 304 ? 13.491  13.249  -17.188 1.000 14.338 0 319  TYR A HB2  1 c 
ATOM   4762 H HB3  . TYR A 1 304 ? 14.487  14.032  -16.215 1.000 14.314 0 319  TYR A HB3  1 c 
ATOM   4763 H HD1  . TYR A 1 304 ? 13.659  16.381  -15.471 1.000 16.093 0 319  TYR A HD1  1 c 
ATOM   4764 H HD2  . TYR A 1 304 ? 11.164  13.540  -16.790 1.000 16.507 0 319  TYR A HD2  1 c 
ATOM   4765 H HE1  . TYR A 1 304 ? 11.880  17.469  -14.468 1.000 17.594 0 319  TYR A HE1  1 c 
ATOM   4766 H HE2  . TYR A 1 304 ? 9.376   14.634  -15.781 1.000 17.604 0 319  TYR A HE2  1 c 
ATOM   4767 H HH   . TYR A 1 304 ? 9.032   17.350  -14.984 0.000 20.070 0 319  TYR A HH   1 c 
ATOM   4768 N N    . PRO A 1 305 ? 16.381  13.782  -19.144 1.000 15.141 0 320  PRO A N    1 ? 
ATOM   4769 C CA   . PRO A 1 305 ? 17.845  13.646  -19.195 1.000 15.697 0 320  PRO A CA   1 ? 
ATOM   4770 C C    . PRO A 1 305 ? 18.511  14.999  -19.436 1.000 16.887 0 320  PRO A C    1 ? 
ATOM   4771 O O    . PRO A 1 305 ? 19.570  15.299  -18.866 1.000 16.022 0 320  PRO A O    1 ? 
ATOM   4772 C CB   . PRO A 1 305 ? 18.030  12.597  -20.303 1.000 15.625 0 320  PRO A CB   1 ? 
ATOM   4773 C CG   . PRO A 1 305 ? 16.760  11.777  -20.148 1.000 16.389 0 320  PRO A CG   1 ? 
ATOM   4774 C CD   . PRO A 1 305 ? 15.662  12.822  -20.003 1.000 15.893 0 320  PRO A CD   1 ? 
ATOM   4775 H HA   . PRO A 1 305 ? 18.158  13.272  -18.336 1.000 15.815 0 320  PRO A HA   1 c 
ATOM   4776 H HB2  . PRO A 1 305 ? 18.079  13.020  -21.193 1.000 15.810 0 320  PRO A HB2  1 c 
ATOM   4777 H HB3  . PRO A 1 305 ? 18.834  12.048  -20.146 1.000 15.810 0 320  PRO A HB3  1 c 
ATOM   4778 H HG2  . PRO A 1 305 ? 16.606  11.216  -20.936 1.000 16.102 0 320  PRO A HG2  1 c 
ATOM   4779 H HG3  . PRO A 1 305 ? 16.806  11.206  -19.353 1.000 16.102 0 320  PRO A HG3  1 c 
ATOM   4780 H HD2  . PRO A 1 305 ? 15.417  13.216  -20.870 1.000 15.814 0 320  PRO A HD2  1 c 
ATOM   4781 H HD3  . PRO A 1 305 ? 14.868  12.453  -19.556 1.000 15.809 0 320  PRO A HD3  1 c 
ATOM   4782 N N    . TYR A 1 306 ? 17.909  15.832  -20.291 1.000 14.324 0 321  TYR A N    1 ? 
ATOM   4783 C CA   . TYR A 1 306 ? 18.479  17.135  -20.588 1.000 14.867 0 321  TYR A CA   1 ? 
ATOM   4784 C C    . TYR A 1 306 ? 18.264  18.082  -19.422 1.000 14.744 0 321  TYR A C    1 ? 
ATOM   4785 O O    . TYR A 1 306 ? 19.079  18.970  -19.181 1.000 15.757 0 321  TYR A O    1 ? 
ATOM   4786 C CB   . TYR A 1 306 ? 17.919  17.688  -21.898 1.000 14.866 0 321  TYR A CB   1 ? 
ATOM   4787 C CG   . TYR A 1 306 ? 18.262  16.814  -23.093 1.000 15.150 0 321  TYR A CG   1 ? 
ATOM   4788 C CD1  . TYR A 1 306 ? 19.514  16.884  -23.663 1.000 17.255 0 321  TYR A CD1  1 ? 
ATOM   4789 C CD2  . TYR A 1 306 ? 17.330  15.977  -23.687 1.000 15.998 0 321  TYR A CD2  1 ? 
ATOM   4790 C CE1  . TYR A 1 306 ? 19.819  16.127  -24.765 1.000 15.277 0 321  TYR A CE1  1 ? 
ATOM   4791 C CE2  . TYR A 1 306 ? 17.625  15.221  -24.790 1.000 16.730 0 321  TYR A CE2  1 ? 
ATOM   4792 C CZ   . TYR A 1 306 ? 18.884  15.307  -25.335 1.000 16.077 0 321  TYR A CZ   1 ? 
ATOM   4793 O OH   . TYR A 1 306 ? 19.225  14.525  -26.416 1.000 17.907 0 321  TYR A OH   1 ? 
ATOM   4794 H H    . TYR A 1 306 ? 17.132  15.583  -20.703 1.000 15.028 0 321  TYR A H    1 c 
ATOM   4795 H HA   . TYR A 1 306 ? 19.460  17.018  -20.707 1.000 14.755 0 321  TYR A HA   1 c 
ATOM   4796 H HB2  . TYR A 1 306 ? 16.943  17.750  -21.820 1.000 14.964 0 321  TYR A HB2  1 c 
ATOM   4797 H HB3  . TYR A 1 306 ? 18.280  18.591  -22.042 1.000 14.937 0 321  TYR A HB3  1 c 
ATOM   4798 H HD1  . TYR A 1 306 ? 20.168  17.454  -23.292 1.000 16.262 0 321  TYR A HD1  1 c 
ATOM   4799 H HD2  . TYR A 1 306 ? 16.461  15.928  -23.321 1.000 15.970 0 321  TYR A HD2  1 c 
ATOM   4800 H HE1  . TYR A 1 306 ? 20.684  16.171  -25.135 1.000 15.922 0 321  TYR A HE1  1 c 
ATOM   4801 H HE2  . TYR A 1 306 ? 16.980  14.646  -25.165 1.000 16.414 0 321  TYR A HE2  1 c 
ATOM   4802 H HH   . TYR A 1 306 ? 19.514  13.763  -26.146 0.000 17.940 0 321  TYR A HH   1 c 
ATOM   4803 N N    . MET A 1 307 ? 17.111  18.014  -18.753 1.000 14.935 0 322  MET A N    1 ? 
ATOM   4804 C CA   . MET A 1 307 ? 16.865  18.813  -17.556 1.000 14.216 0 322  MET A CA   1 ? 
ATOM   4805 C C    . MET A 1 307 ? 17.871  18.520  -16.427 1.000 15.143 0 322  MET A C    1 ? 
ATOM   4806 O O    . MET A 1 307 ? 18.367  19.438  -15.783 1.000 15.998 0 322  MET A O    1 ? 
ATOM   4807 C CB   . MET A 1 307 ? 15.447  18.623  -16.990 1.000 14.684 0 322  MET A CB   1 ? 
ATOM   4808 C CG   . MET A 1 307 ? 14.357  19.167  -17.880 1.000 16.638 0 322  MET A CG   1 ? 
ATOM   4809 S SD   . MET A 1 307 ? 14.251  20.960  -17.682 1.000 18.733 0 322  MET A SD   1 ? 
ATOM   4810 C CE   . MET A 1 307 ? 12.809  21.252  -18.719 1.000 19.620 0 322  MET A CE   1 ? 
ATOM   4811 H H    . MET A 1 307 ? 16.450  17.458  -19.052 1.000 14.723 0 322  MET A H    1 c 
ATOM   4812 H HA   . MET A 1 307 ? 16.977  19.765  -17.811 1.000 14.627 0 322  MET A HA   1 c 
ATOM   4813 H HB2  . MET A 1 307 ? 15.293  17.666  -16.847 1.000 15.004 0 322  MET A HB2  1 c 
ATOM   4814 H HB3  . MET A 1 307 ? 15.395  19.067  -16.117 1.000 15.026 0 322  MET A HB3  1 c 
ATOM   4815 H HG2  . MET A 1 307 ? 14.552  18.954  -18.814 1.000 16.503 0 322  MET A HG2  1 c 
ATOM   4816 H HG3  . MET A 1 307 ? 13.499  18.762  -17.642 1.000 16.510 0 322  MET A HG3  1 c 
ATOM   4817 H HE1  . MET A 1 307 ? 12.604  22.205  -18.729 1.000 19.395 0 322  MET A HE1  1 c 
ATOM   4818 H HE2  . MET A 1 307 ? 12.996  20.950  -19.627 1.000 19.395 0 322  MET A HE2  1 c 
ATOM   4819 H HE3  . MET A 1 307 ? 12.048  20.759  -18.363 1.000 19.395 0 322  MET A HE3  1 c 
ATOM   4820 N N    . TYR A 1 308 ? 18.204  17.235  -16.188 1.000 14.950 0 323  TYR A N    1 ? 
ATOM   4821 C CA   . TYR A 1 308 ? 19.195  16.858  -15.192 1.000 15.408 0 323  TYR A CA   1 ? 
ATOM   4822 C C    . TYR A 1 308 ? 20.505  17.605  -15.501 1.000 16.193 0 323  TYR A C    1 ? 
ATOM   4823 O O    . TYR A 1 308 ? 21.144  18.159  -14.613 1.000 15.427 0 323  TYR A O    1 ? 
ATOM   4824 C CB   . TYR A 1 308 ? 19.388  15.339  -15.123 1.000 15.356 0 323  TYR A CB   1 ? 
ATOM   4825 C CG   . TYR A 1 308 ? 18.462  14.559  -14.186 1.000 14.409 0 323  TYR A CG   1 ? 
ATOM   4826 C CD1  . TYR A 1 308 ? 18.764  14.444  -12.837 1.000 16.352 0 323  TYR A CD1  1 ? 
ATOM   4827 C CD2  . TYR A 1 308 ? 17.350  13.880  -14.666 1.000 18.001 0 323  TYR A CD2  1 ? 
ATOM   4828 C CE1  . TYR A 1 308 ? 17.969  13.703  -11.974 1.000 17.313 0 323  TYR A CE1  1 ? 
ATOM   4829 C CE2  . TYR A 1 308 ? 16.540  13.168  -13.808 1.000 16.773 0 323  TYR A CE2  1 ? 
ATOM   4830 C CZ   . TYR A 1 308 ? 16.857  13.058  -12.461 1.000 17.650 0 323  TYR A CZ   1 ? 
ATOM   4831 O OH   . TYR A 1 308 ? 16.004  12.330  -11.643 1.000 18.364 0 323  TYR A OH   1 ? 
ATOM   4832 H H    . TYR A 1 308 ? 17.789  16.575  -16.665 1.000 15.094 0 323  TYR A H    1 c 
ATOM   4833 H HA   . TYR A 1 308 ? 18.867  17.165  -14.305 1.000 15.447 0 323  TYR A HA   1 c 
ATOM   4834 H HB2  . TYR A 1 308 ? 19.285  14.978  -16.031 1.000 15.152 0 323  TYR A HB2  1 c 
ATOM   4835 H HB3  . TYR A 1 308 ? 20.316  15.164  -14.853 1.000 15.172 0 323  TYR A HB3  1 c 
ATOM   4836 H HD1  . TYR A 1 308 ? 19.532  14.875  -12.497 1.000 16.118 0 323  TYR A HD1  1 c 
ATOM   4837 H HD2  . TYR A 1 308 ? 17.124  13.937  -15.579 1.000 16.801 0 323  TYR A HD2  1 c 
ATOM   4838 H HE1  . TYR A 1 308 ? 18.181  13.653  -11.058 1.000 17.174 0 323  TYR A HE1  1 c 
ATOM   4839 H HE2  . TYR A 1 308 ? 15.780  12.724  -14.145 1.000 17.236 0 323  TYR A HE2  1 c 
ATOM   4840 H HH   . TYR A 1 308 ? 15.383  12.837  -11.338 0.000 18.370 0 323  TYR A HH   1 c 
ATOM   4841 N N    . LEU A 1 309 ? 20.937  17.511  -16.765 1.000 15.299 0 324  LEU A N    1 ? 
ATOM   4842 C CA   . LEU A 1 309 ? 22.181  18.172  -17.194 1.000 15.954 0 324  LEU A CA   1 ? 
ATOM   4843 C C    . LEU A 1 309 ? 22.076  19.690  -17.018 1.000 15.062 0 324  LEU A C    1 ? 
ATOM   4844 O O    . LEU A 1 309 ? 22.991  20.341  -16.503 1.000 15.245 0 324  LEU A O    1 ? 
ATOM   4845 C CB   . LEU A 1 309 ? 22.479  17.787  -18.631 1.000 16.877 0 324  LEU A CB   1 ? 
ATOM   4846 C CG   . LEU A 1 309 ? 23.709  18.451  -19.272 1.000 14.953 0 324  LEU A CG   1 ? 
ATOM   4847 C CD1  . LEU A 1 309 ? 24.946  18.094  -18.471 1.000 16.221 0 324  LEU A CD1  1 ? 
ATOM   4848 C CD2  . LEU A 1 309 ? 23.777  18.075  -20.723 1.000 16.680 0 324  LEU A CD2  1 ? 
ATOM   4849 H H    . LEU A 1 309 ? 20.459  17.026  -17.374 1.000 15.659 0 324  LEU A H    1 c 
ATOM   4850 H HA   . LEU A 1 309 ? 22.914  17.844  -16.615 1.000 15.822 0 324  LEU A HA   1 c 
ATOM   4851 H HB2  . LEU A 1 309 ? 22.601  16.810  -18.667 1.000 16.210 0 324  LEU A HB2  1 c 
ATOM   4852 H HB3  . LEU A 1 309 ? 21.689  18.006  -19.177 1.000 16.209 0 324  LEU A HB3  1 c 
ATOM   4853 H HG   . LEU A 1 309 ? 23.590  19.435  -19.223 1.000 15.842 0 324  LEU A HG   1 c 
ATOM   4854 H HD11 . LEU A 1 309 ? 24.925  18.554  -17.615 1.000 15.835 0 324  LEU A HD11 1 c 
ATOM   4855 H HD12 . LEU A 1 309 ? 25.740  18.363  -18.962 1.000 15.835 0 324  LEU A HD12 1 c 
ATOM   4856 H HD13 . LEU A 1 309 ? 24.969  17.133  -18.321 1.000 15.835 0 324  LEU A HD13 1 c 
ATOM   4857 H HD21 . LEU A 1 309 ? 22.967  18.368  -21.174 1.000 16.146 0 324  LEU A HD21 1 c 
ATOM   4858 H HD22 . LEU A 1 309 ? 23.861  17.110  -20.805 1.000 16.153 0 324  LEU A HD22 1 c 
ATOM   4859 H HD23 . LEU A 1 309 ? 24.548  18.501  -21.134 1.000 16.146 0 324  LEU A HD23 1 c 
ATOM   4860 N N    . ALA A 1 310 ? 20.978  20.283  -17.481 1.000 14.988 0 325  ALA A N    1 ? 
ATOM   4861 C CA   . ALA A 1 310 ? 20.831  21.738  -17.357 1.000 16.058 0 325  ALA A CA   1 ? 
ATOM   4862 C C    . ALA A 1 310 ? 20.909  22.180  -15.901 1.000 16.360 0 325  ALA A C    1 ? 
ATOM   4863 O O    . ALA A 1 310 ? 21.502  23.228  -15.597 1.000 17.147 0 325  ALA A O    1 ? 
ATOM   4864 C CB   . ALA A 1 310 ? 19.524  22.171  -18.007 1.000 16.512 0 325  ALA A CB   1 ? 
ATOM   4865 H H    . ALA A 1 310 ? 20.317  19.793  -17.880 1.000 15.251 0 325  ALA A H    1 c 
ATOM   4866 H HA   . ALA A 1 310 ? 21.587  22.165  -17.847 1.000 15.977 0 325  ALA A HA   1 c 
ATOM   4867 H HB1  . ALA A 1 310 ? 19.455  21.782  -18.895 1.000 16.377 0 325  ALA A HB1  1 c 
ATOM   4868 H HB2  . ALA A 1 310 ? 18.775  21.870  -17.466 1.000 16.378 0 325  ALA A HB2  1 c 
ATOM   4869 H HB3  . ALA A 1 310 ? 19.500  23.140  -18.078 1.000 16.378 0 325  ALA A HB3  1 c 
ATOM   4870 N N    . GLY A 1 311 ? 20.279  21.418  -14.989 1.000 15.154 0 326  GLY A N    1 ? 
ATOM   4871 C CA   . GLY A 1 311 ? 20.293  21.801  -13.575 1.000 15.966 0 326  GLY A CA   1 ? 
ATOM   4872 C C    . GLY A 1 311 ? 21.702  21.821  -13.006 1.000 16.790 0 326  GLY A C    1 ? 
ATOM   4873 O O    . GLY A 1 311 ? 22.076  22.734  -12.294 1.000 18.114 0 326  GLY A O    1 ? 
ATOM   4874 H H    . GLY A 1 311 ? 19.835  20.661  -15.245 1.000 15.613 0 326  GLY A H    1 c 
ATOM   4875 H HA2  . GLY A 1 311 ? 19.888  22.695  -13.480 1.000 15.955 0 326  GLY A HA2  1 c 
ATOM   4876 H HA3  . GLY A 1 311 ? 19.742  21.163  -13.063 1.000 15.951 0 326  GLY A HA3  1 c 
ATOM   4877 N N    . TYR A 1 312 ? 22.465  20.817  -13.333 1.000 16.768 0 327  TYR A N    1 ? 
ATOM   4878 C CA   . TYR A 1 312 ? 23.858  20.784  -12.914 1.000 17.572 0 327  TYR A CA   1 ? 
ATOM   4879 C C    . TYR A 1 312 ? 24.615  22.009  -13.421 1.000 17.628 0 327  TYR A C    1 ? 
ATOM   4880 O O    . TYR A 1 312 ? 25.299  22.677  -12.637 1.000 19.221 0 327  TYR A O    1 ? 
ATOM   4881 C CB   . TYR A 1 312 ? 24.504  19.507  -13.445 1.000 17.748 0 327  TYR A CB   1 ? 
ATOM   4882 C CG   . TYR A 1 312 ? 25.998  19.463  -13.164 1.000 20.168 0 327  TYR A CG   1 ? 
ATOM   4883 C CD1  . TYR A 1 312 ? 26.451  19.006  -11.939 1.000 22.050 0 327  TYR A CD1  1 ? 
ATOM   4884 C CD2  . TYR A 1 312 ? 26.925  19.779  -14.141 1.000 23.359 0 327  TYR A CD2  1 ? 
ATOM   4885 C CE1  . TYR A 1 312 ? 27.803  18.900  -11.680 1.000 25.516 0 327  TYR A CE1  1 ? 
ATOM   4886 C CE2  . TYR A 1 312 ? 28.288  19.703  -13.877 1.000 26.322 0 327  TYR A CE2  1 ? 
ATOM   4887 C CZ   . TYR A 1 312 ? 28.709  19.221  -12.660 1.000 27.907 0 327  TYR A CZ   1 ? 
ATOM   4888 O OH   . TYR A 1 312 ? 30.048  19.124  -12.373 1.000 33.652 0 327  TYR A OH   1 ? 
ATOM   4889 H H    . TYR A 1 312 ? 22.128  20.122  -13.822 1.000 16.945 0 327  TYR A H    1 c 
ATOM   4890 H HA   . TYR A 1 312 ? 23.892  20.772  -11.921 1.000 17.501 0 327  TYR A HA   1 c 
ATOM   4891 H HB2  . TYR A 1 312 ? 24.073  18.733  -13.020 1.000 18.222 0 327  TYR A HB2  1 c 
ATOM   4892 H HB3  . TYR A 1 312 ? 24.356  19.454  -14.414 1.000 18.205 0 327  TYR A HB3  1 c 
ATOM   4893 H HD1  . TYR A 1 312 ? 25.828  18.755  -11.275 1.000 22.401 0 327  TYR A HD1  1 c 
ATOM   4894 H HD2  . TYR A 1 312 ? 26.631  20.086  -14.984 1.000 23.230 0 327  TYR A HD2  1 c 
ATOM   4895 H HE1  . TYR A 1 312 ? 28.103  18.592  -10.842 1.000 25.169 0 327  TYR A HE1  1 c 
ATOM   4896 H HE2  . TYR A 1 312 ? 28.916  19.920  -14.545 1.000 25.934 0 327  TYR A HE2  1 c 
ATOM   4897 H HH   . TYR A 1 312 ? 30.334  18.340  -12.567 0.000 33.530 0 327  TYR A HH   1 c 
ATOM   4898 N N    . HIS A 1 313 ? 24.465  22.338  -14.717 1.000 17.396 0 328  HIS A N    1 ? 
ATOM   4899 C CA   . HIS A 1 313 ? 25.128  23.525  -15.241 1.000 18.625 0 328  HIS A CA   1 ? 
ATOM   4900 C C    . HIS A 1 313 ? 24.628  24.817  -14.597 1.000 19.139 0 328  HIS A C    1 ? 
ATOM   4901 O O    . HIS A 1 313 ? 25.411  25.752  -14.330 1.000 20.315 0 328  HIS A O    1 ? 
ATOM   4902 C CB   . HIS A 1 313 ? 25.077  23.575  -16.756 1.000 17.556 0 328  HIS A CB   1 ? 
ATOM   4903 C CG   . HIS A 1 313 ? 25.930  22.576  -17.441 1.000 18.339 0 328  HIS A CG   1 ? 
ATOM   4904 N ND1  . HIS A 1 313 ? 27.283  22.528  -17.187 1.000 18.792 0 328  HIS A ND1  1 ? 
ATOM   4905 C CD2  . HIS A 1 313 ? 25.706  21.665  -18.375 1.000 19.500 0 328  HIS A CD2  1 ? 
ATOM   4906 C CE1  . HIS A 1 313 ? 27.821  21.631  -17.983 1.000 18.169 0 328  HIS A CE1  1 ? 
ATOM   4907 N NE2  . HIS A 1 313 ? 26.901  21.095  -18.715 1.000 20.037 0 328  HIS A NE2  1 ? 
ATOM   4908 H H    . HIS A 1 313 ? 23.954  21.823  -15.273 1.000 17.712 0 328  HIS A H    1 c 
ATOM   4909 H HA   . HIS A 1 313 ? 26.082  23.429  -15.000 1.000 18.273 0 328  HIS A HA   1 c 
ATOM   4910 H HB2  . HIS A 1 313 ? 24.146  23.444  -17.041 1.000 17.995 0 328  HIS A HB2  1 c 
ATOM   4911 H HB3  . HIS A 1 313 ? 25.347  24.473  -17.048 1.000 18.074 0 328  HIS A HB3  1 c 
ATOM   4912 H HD1  . HIS A 1 313 ? 27.716  23.058  -16.630 0.000 18.800 0 328  HIS A HD1  1 c 
ATOM   4913 H HD2  . HIS A 1 313 ? 24.881  21.473  -18.775 1.000 19.321 0 328  HIS A HD2  1 c 
ATOM   4914 H HE1  . HIS A 1 313 ? 28.732  21.391  -17.984 1.000 18.741 0 328  HIS A HE1  1 c 
ATOM   4915 H HE2  . HIS A 1 313 ? 27.027  20.469  -19.317 0.000 20.000 0 328  HIS A HE2  1 c 
ATOM   4916 N N    . CYS A 1 314 ? 23.334  24.892  -14.319 1.000 17.633 0 329  CYS A N    1 ? 
ATOM   4917 C CA   . CYS A 1 314 ? 22.723  26.033  -13.643 1.000 19.772 0 329  CYS A CA   1 ? 
ATOM   4918 C C    . CYS A 1 314 ? 23.322  26.208  -12.256 1.000 22.146 0 329  CYS A C    1 ? 
ATOM   4919 O O    . CYS A 1 314 ? 23.755  27.310  -11.894 1.000 23.709 0 329  CYS A O    1 ? 
ATOM   4920 C CB   . CYS A 1 314 ? 21.210  25.845  -13.621 1.000 22.441 0 329  CYS A CB   1 ? 
ATOM   4921 S SG   . CYS A 1 314 ? 20.354  27.274  -12.925 1.000 23.976 0 329  CYS A SG   1 ? 
ATOM   4922 H H    . CYS A 1 314 ? 22.794  24.199  -14.568 1.000 18.471 0 329  CYS A H    1 c 
ATOM   4923 H HA   . CYS A 1 314 ? 22.926  26.844  -14.174 1.000 20.207 0 329  CYS A HA   1 c 
ATOM   4924 H HB2  . CYS A 1 314 ? 20.887  25.698  -14.537 1.000 22.045 0 329  CYS A HB2  1 c 
ATOM   4925 H HB3  . CYS A 1 314 ? 20.988  25.052  -13.085 1.000 22.026 0 329  CYS A HB3  1 c 
ATOM   4926 H HG   . CYS A 1 314 ? 19.224  26.853  -13.037 0.000 23.990 0 329  CYS A HG   1 c 
ATOM   4927 N N    . ARG A 1 315 ? 23.378  25.127  -11.475 1.000 20.226 0 330  ARG A N    1 ? 
ATOM   4928 C CA   . ARG A 1 315 ? 23.917  25.198  -10.127 1.000 20.873 0 330  ARG A CA   1 ? 
ATOM   4929 C C    . ARG A 1 315 ? 25.377  25.644  -10.152 1.000 21.857 0 330  ARG A C    1 ? 
ATOM   4930 O O    . ARG A 1 315 ? 25.811  26.291  -9.191  1.000 26.157 0 330  ARG A O    1 ? 
ATOM   4931 C CB   . ARG A 1 315 ? 23.822  23.854  -9.417  1.000 20.159 0 330  ARG A CB   1 ? 
ATOM   4932 C CG   . ARG A 1 315 ? 22.418  23.448  -9.000  1.000 20.565 0 330  ARG A CG   1 ? 
ATOM   4933 C CD   . ARG A 1 315 ? 22.311  22.144  -8.184  1.000 22.007 0 330  ARG A CD   1 ? 
ATOM   4934 N NE   . ARG A 1 315 ? 22.854  20.953  -8.850  1.000 21.605 0 330  ARG A NE   1 ? 
ATOM   4935 C CZ   . ARG A 1 315 ? 22.121  20.182  -9.680  1.000 22.599 0 330  ARG A CZ   1 ? 
ATOM   4936 N NH1  . ARG A 1 315 ? 20.915  20.565  -10.009 1.000 25.691 0 330  ARG A NH1  1 ? 
ATOM   4937 N NH2  . ARG A 1 315 ? 22.622  19.094  -10.182 1.000 23.324 0 330  ARG A NH2  1 ? 
ATOM   4938 H H    . ARG A 1 315 ? 23.068  24.325  -11.787 1.000 20.779 0 330  ARG A H    1 c 
ATOM   4939 H HA   . ARG A 1 315 ? 23.392  25.866  -9.617  1.000 20.787 0 330  ARG A HA   1 c 
ATOM   4940 H HB2  . ARG A 1 315 ? 24.184  23.162  -10.010 1.000 20.417 0 330  ARG A HB2  1 c 
ATOM   4941 H HB3  . ARG A 1 315 ? 24.389  23.883  -8.616  1.000 20.421 0 330  ARG A HB3  1 c 
ATOM   4942 H HG2  . ARG A 1 315 ? 22.027  24.178  -8.471  1.000 20.788 0 330  ARG A HG2  1 c 
ATOM   4943 H HG3  . ARG A 1 315 ? 21.866  23.357  -9.806  1.000 20.795 0 330  ARG A HG3  1 c 
ATOM   4944 H HD2  . ARG A 1 315 ? 22.786  22.275  -7.338  1.000 21.595 0 330  ARG A HD2  1 c 
ATOM   4945 H HD3  . ARG A 1 315 ? 21.370  21.988  -7.967  1.000 21.656 0 330  ARG A HD3  1 c 
ATOM   4946 H HE   . ARG A 1 315 ? 23.684  20.740  -8.705  1.000 21.988 0 330  ARG A HE   1 c 
ATOM   4947 H HH11 . ARG A 1 315 ? 20.232  20.020  -9.872  1.000 24.672 0 330  ARG A HH11 1 c 
ATOM   4948 H HH12 . ARG A 1 315 ? 20.785  21.363  -10.365 1.000 24.591 0 330  ARG A HH12 1 c 
ATOM   4949 H HH21 . ARG A 1 315 ? 22.140  18.604  -10.738 1.000 23.112 0 330  ARG A HH21 1 c 
ATOM   4950 H HH22 . ARG A 1 315 ? 23.443  18.845  -9.967  1.000 23.081 0 330  ARG A HH22 1 c 
ATOM   4951 N N    . ASN A 1 316 ? 26.134  25.224  -11.161 1.000 20.896 0 331  ASN A N    1 ? 
ATOM   4952 C CA   . ASN A 1 316 ? 27.547  25.530  -11.280 1.000 21.937 0 331  ASN A CA   1 ? 
ATOM   4953 C C    . ASN A 1 316 ? 27.769  26.850  -12.037 1.000 24.726 0 331  ASN A C    1 ? 
ATOM   4954 O O    . ASN A 1 316 ? 28.925  27.182  -12.314 1.000 29.688 0 331  ASN A O    1 ? 
ATOM   4955 C CB   . ASN A 1 316 ? 28.311  24.365  -11.877 1.000 24.270 0 331  ASN A CB   1 ? 
ATOM   4956 C CG   . ASN A 1 316 ? 28.369  23.223  -10.899 1.000 28.678 0 331  ASN A CG   1 ? 
ATOM   4957 O OD1  . ASN A 1 316 ? 29.146  23.297  -9.949  1.000 32.063 0 331  ASN A OD1  1 ? 
ATOM   4958 N ND2  . ASN A 1 316 ? 27.512  22.225  -11.033 1.000 28.311 0 331  ASN A ND2  1 ? 
ATOM   4959 H H    . ASN A 1 316 ? 25.750  24.709  -11.811 1.000 21.388 0 331  ASN A H    1 c 
ATOM   4960 H HA   . ASN A 1 316 ? 27.897  25.658  -10.369 1.000 22.722 0 331  ASN A HA   1 c 
ATOM   4961 H HB2  . ASN A 1 316 ? 27.870  24.071  -12.699 1.000 24.653 0 331  ASN A HB2  1 c 
ATOM   4962 H HB3  . ASN A 1 316 ? 29.220  24.649  -12.099 1.000 24.675 0 331  ASN A HB3  1 c 
ATOM   4963 H HD21 . ASN A 1 316 ? 26.894  22.251  -11.669 1.000 28.289 0 331  ASN A HD21 1 c 
ATOM   4964 H HD22 . ASN A 1 316 ? 27.556  21.529  -10.485 1.000 28.417 0 331  ASN A HD22 1 c 
ATOM   4965 N N    . ARG A 1 317 ? 26.696  27.547  -12.436 1.000 26.170 0 332  ARG A N    1 ? 
ATOM   4966 C CA   . ARG A 1 317 ? 26.783  28.794  -13.224 1.000 30.826 0 332  ARG A CA   1 ? 
ATOM   4967 C C    . ARG A 1 317 ? 27.586  28.637  -14.511 1.000 33.174 0 332  ARG A C    1 ? 
ATOM   4968 O O    . ARG A 1 317 ? 28.300  29.547  -14.977 1.000 30.485 0 332  ARG A O    1 ? 
ATOM   4969 C CB   . ARG A 1 317 ? 27.329  29.958  -12.391 1.000 29.938 0 332  ARG A CB   1 ? 
ATOM   4970 C CG   . ARG A 1 317 ? 26.419  30.276  -11.226 1.000 31.381 0 332  ARG A CG   1 ? 
ATOM   4971 C CD   . ARG A 1 317 ? 24.997  30.616  -11.632 1.000 34.195 0 332  ARG A CD   1 ? 
ATOM   4972 N NE   . ARG A 1 317 ? 24.285  31.138  -10.461 1.000 35.734 0 332  ARG A NE   1 ? 
ATOM   4973 C CZ   . ARG A 1 317 ? 23.529  30.467  -9.612  1.000 41.978 0 332  ARG A CZ   1 ? 
ATOM   4974 N NH1  . ARG A 1 317 ? 23.383  29.154  -9.738  1.000 40.048 0 332  ARG A NH1  1 ? 
ATOM   4975 N NH2  . ARG A 1 317 ? 22.938  31.096  -8.602  1.000 39.423 0 332  ARG A NH2  1 ? 
ATOM   4976 H H    . ARG A 1 317 ? 25.866  27.240  -12.213 1.000 26.631 0 332  ARG A H    1 c 
ATOM   4977 H HA   . ARG A 1 317 ? 25.861  29.035  -13.491 1.000 30.160 0 332  ARG A HA   1 c 
ATOM   4978 H HB2  . ARG A 1 317 ? 28.220  29.728  -12.051 1.000 30.434 0 332  ARG A HB2  1 c 
ATOM   4979 H HB3  . ARG A 1 317 ? 27.414  30.754  -12.957 1.000 30.471 0 332  ARG A HB3  1 c 
ATOM   4980 H HG2  . ARG A 1 317 ? 26.398  29.506  -10.618 1.000 31.629 0 332  ARG A HG2  1 c 
ATOM   4981 H HG3  . ARG A 1 317 ? 26.794  31.035  -10.728 1.000 31.654 0 332  ARG A HG3  1 c 
ATOM   4982 H HD2  . ARG A 1 317 ? 25.003  31.293  -12.340 1.000 33.892 0 332  ARG A HD2  1 c 
ATOM   4983 H HD3  . ARG A 1 317 ? 24.536  29.821  -11.966 1.000 33.893 0 332  ARG A HD3  1 c 
ATOM   4984 H HE   . ARG A 1 317 ? 24.369  31.991  -10.303 1.000 36.786 0 332  ARG A HE   1 c 
ATOM   4985 H HH11 . ARG A 1 317 ? 22.578  28.792  -9.646  1.000 40.608 0 332  ARG A HH11 1 c 
ATOM   4986 H HH12 . ARG A 1 317 ? 24.090  28.645  -9.910  1.000 40.530 0 332  ARG A HH12 1 c 
ATOM   4987 H HH21 . ARG A 1 317 ? 22.811  30.672  -7.837  1.000 40.184 0 332  ARG A HH21 1 c 
ATOM   4988 H HH22 . ARG A 1 317 ? 22.672  31.934  -8.699  1.000 40.162 0 332  ARG A HH22 1 c 
ATOM   4989 N N    . ASN A 1 318 ? 27.380  27.512  -15.181 1.000 27.356 0 333  ASN A N    1 ? 
ATOM   4990 C CA   . ASN A 1 318 ? 27.885  27.354  -16.527 1.000 27.302 0 333  ASN A CA   1 ? 
ATOM   4991 C C    . ASN A 1 318 ? 26.739  27.813  -17.439 1.000 28.039 0 333  ASN A C    1 ? 
ATOM   4992 O O    . ASN A 1 318 ? 26.002  26.951  -17.902 1.000 24.165 0 333  ASN A O    1 ? 
ATOM   4993 C CB   . ASN A 1 318 ? 28.335  25.923  -16.845 1.000 30.066 0 333  ASN A CB   1 ? 
ATOM   4994 C CG   . ASN A 1 318 ? 29.394  25.361  -15.910 1.000 36.963 0 333  ASN A CG   1 ? 
ATOM   4995 O OD1  . ASN A 1 318 ? 30.262  26.120  -15.449 1.000 38.004 0 333  ASN A OD1  1 ? 
ATOM   4996 N ND2  . ASN A 1 318 ? 29.340  24.061  -15.599 1.000 31.765 0 333  ASN A ND2  1 ? 
ATOM   4997 H H    . ASN A 1 318 ? 26.912  26.826  -14.798 1.000 28.607 0 333  ASN A H    1 c 
ATOM   4998 H HA   . ASN A 1 318 ? 28.658  27.949  -16.654 1.000 28.021 0 333  ASN A HA   1 c 
ATOM   4999 H HB2  . ASN A 1 318 ? 27.554  25.335  -16.814 1.000 30.701 0 333  ASN A HB2  1 c 
ATOM   5000 H HB3  . ASN A 1 318 ? 28.684  25.900  -17.756 1.000 30.846 0 333  ASN A HB3  1 c 
ATOM   5001 H HD21 . ASN A 1 318 ? 28.630  23.736  -15.176 1.000 33.156 0 333  ASN A HD21 1 c 
ATOM   5002 H HD22 . ASN A 1 318 ? 30.015  23.526  -15.815 1.000 33.253 0 333  ASN A HD22 1 c 
ATOM   5003 N N    . VAL A 1 319 ? 26.544  29.125  -17.635 1.000 24.215 0 334  VAL A N    1 ? 
ATOM   5004 C CA   . VAL A 1 319 ? 25.321  29.652  -18.260 1.000 24.544 0 334  VAL A CA   1 ? 
ATOM   5005 C C    . VAL A 1 319 ? 25.211  29.154  -19.700 1.000 21.006 0 334  VAL A C    1 ? 
ATOM   5006 O O    . VAL A 1 319 ? 24.130  28.746  -20.142 1.000 19.545 0 334  VAL A O    1 ? 
ATOM   5007 C CB   . VAL A 1 319 ? 25.210  31.199  -18.196 1.000 23.692 0 334  VAL A CB   1 ? 
ATOM   5008 C CG1  . VAL A 1 319 ? 24.045  31.767  -18.999 1.000 24.019 0 334  VAL A CG1  1 ? 
ATOM   5009 C CG2  . VAL A 1 319 ? 25.154  31.718  -16.751 1.000 27.583 0 334  VAL A CG2  1 ? 
ATOM   5010 H H    . VAL A 1 319 ? 27.192  29.714  -17.373 1.000 25.165 0 334  VAL A H    1 c 
ATOM   5011 H HA   . VAL A 1 319 ? 24.563  29.285  -17.765 1.000 23.648 0 334  VAL A HA   1 c 
ATOM   5012 H HB   . VAL A 1 319 ? 26.035  31.558  -18.598 1.000 24.678 0 334  VAL A HB   1 c 
ATOM   5013 H HG11 . VAL A 1 319 ? 23.232  31.279  -18.783 1.000 23.927 0 334  VAL A HG11 1 c 
ATOM   5014 H HG12 . VAL A 1 319 ? 24.231  31.681  -19.950 1.000 23.914 0 334  VAL A HG12 1 c 
ATOM   5015 H HG13 . VAL A 1 319 ? 23.926  32.706  -18.779 1.000 23.954 0 334  VAL A HG13 1 c 
ATOM   5016 H HG21 . VAL A 1 319 ? 25.105  32.689  -16.756 1.000 26.360 0 334  VAL A HG21 1 c 
ATOM   5017 H HG22 . VAL A 1 319 ? 25.953  31.438  -16.274 1.000 26.358 0 334  VAL A HG22 1 c 
ATOM   5018 H HG23 . VAL A 1 319 ? 24.369  31.357  -16.306 1.000 26.374 0 334  VAL A HG23 1 c 
ATOM   5019 N N    . ARG A 1 320 ? 26.310  29.173  -20.480 1.000 19.440 0 335  ARG A N    1 ? 
ATOM   5020 C CA   . ARG A 1 320 ? 26.334  28.661  -21.829 1.000 20.408 0 335  ARG A CA   1 ? 
ATOM   5021 C C    . ARG A 1 320 ? 25.807  27.215  -21.906 1.000 20.211 0 335  ARG A C    1 ? 
ATOM   5022 O O    . ARG A 1 320 ? 24.918  26.888  -22.710 1.000 19.626 0 335  ARG A O    1 ? 
ATOM   5023 C CB   . ARG A 1 320 ? 27.732  28.697  -22.497 1.000 23.807 0 335  ARG A CB   1 ? 
ATOM   5024 C CG   . ARG A 1 320 ? 27.733  28.257  -23.941 1.000 27.320 0 335  ARG A CG   1 ? 
ATOM   5025 C CD   . ARG A 1 320 ? 29.092  28.399  -24.665 1.000 34.991 0 335  ARG A CD   1 ? 
ATOM   5026 N NE   . ARG A 1 320 ? 30.002  27.308  -24.315 1.000 43.358 0 335  ARG A NE   1 ? 
ATOM   5027 C CZ   . ARG A 1 320 ? 29.824  26.000  -24.591 1.000 51.354 0 335  ARG A CZ   1 ? 
ATOM   5028 N NH1  . ARG A 1 320 ? 28.792  25.561  -25.297 1.000 51.625 0 335  ARG A NH1  1 ? 
ATOM   5029 N NH2  . ARG A 1 320 ? 30.693  25.115  -24.129 1.000 58.842 0 335  ARG A NH2  1 ? 
ATOM   5030 H H    . ARG A 1 320 ? 27.079  29.533  -20.142 1.000 20.095 0 335  ARG A H    1 c 
ATOM   5031 H HA   . ARG A 1 320 ? 25.731  29.228  -22.372 1.000 20.789 0 335  ARG A HA   1 c 
ATOM   5032 H HB2  . ARG A 1 320 ? 28.083  29.612  -22.446 1.000 23.746 0 335  ARG A HB2  1 c 
ATOM   5033 H HB3  . ARG A 1 320 ? 28.339  28.117  -21.990 1.000 23.746 0 335  ARG A HB3  1 c 
ATOM   5034 H HG2  . ARG A 1 320 ? 27.451  27.319  -23.986 1.000 28.121 0 335  ARG A HG2  1 c 
ATOM   5035 H HG3  . ARG A 1 320 ? 27.062  28.780  -24.431 1.000 28.018 0 335  ARG A HG3  1 c 
ATOM   5036 H HD2  . ARG A 1 320 ? 28.950  28.404  -25.633 1.000 34.888 0 335  ARG A HD2  1 c 
ATOM   5037 H HD3  . ARG A 1 320 ? 29.502  29.253  -24.416 1.000 34.863 0 335  ARG A HD3  1 c 
ATOM   5038 H HE   . ARG A 1 320 ? 30.731  27.523  -23.889 1.000 43.120 0 335  ARG A HE   1 c 
ATOM   5039 H HH11 . ARG A 1 320 ? 28.407  24.795  -25.079 1.000 51.446 0 335  ARG A HH11 1 c 
ATOM   5040 H HH12 . ARG A 1 320 ? 28.493  26.032  -25.984 1.000 51.404 0 335  ARG A HH12 1 c 
ATOM   5041 H HH21 . ARG A 1 320 ? 30.635  24.270  -24.383 1.000 56.289 0 335  ARG A HH21 1 c 
ATOM   5042 H HH22 . ARG A 1 320 ? 31.328  25.369  -23.569 1.000 56.162 0 335  ARG A HH22 1 c 
ATOM   5043 N N    . GLU A 1 321 ? 26.387  26.335  -21.067 1.000 20.369 0 336  GLU A N    1 ? 
ATOM   5044 C CA   . GLU A 1 321 ? 26.030  24.935  -21.098 1.000 20.689 0 336  GLU A CA   1 ? 
ATOM   5045 C C    . GLU A 1 321 ? 24.609  24.700  -20.578 1.000 16.787 0 336  GLU A C    1 ? 
ATOM   5046 O O    . GLU A 1 321 ? 23.963  23.775  -21.103 1.000 17.275 0 336  GLU A O    1 ? 
ATOM   5047 C CB   . GLU A 1 321 ? 27.020  24.100  -20.297 1.000 21.776 0 336  GLU A CB   1 ? 
ATOM   5048 C CG   . GLU A 1 321 ? 28.414  24.148  -20.903 1.000 24.828 0 336  GLU A CG   1 ? 
ATOM   5049 C CD   . GLU A 1 321 ? 29.196  25.429  -20.685 1.000 28.798 0 336  GLU A CD   1 ? 
ATOM   5050 O OE1  . GLU A 1 321 ? 28.964  26.384  -19.889 1.000 34.385 0 336  GLU A OE1  1 ? 
ATOM   5051 O OE2  . GLU A 1 321 ? 30.196  25.400  -21.446 1.000 47.837 0 336  GLU A OE2  1 ? 
ATOM   5052 H H    . GLU A 1 321 ? 26.997  26.627  -20.452 1.000 20.474 0 336  GLU A H    1 c 
ATOM   5053 H HA   . GLU A 1 321 ? 26.068  24.630  -22.041 1.000 20.049 0 336  GLU A HA   1 c 
ATOM   5054 H HB2  . GLU A 1 321 ? 27.044  24.429  -19.374 1.000 22.142 0 336  GLU A HB2  1 c 
ATOM   5055 H HB3  . GLU A 1 321 ? 26.709  23.172  -20.280 1.000 22.112 0 336  GLU A HB3  1 c 
ATOM   5056 H HG2  . GLU A 1 321 ? 28.939  23.404  -20.536 1.000 24.948 0 336  GLU A HG2  1 c 
ATOM   5057 H HG3  . GLU A 1 321 ? 28.340  23.996  -21.869 1.000 25.010 0 336  GLU A HG3  1 c 
ATOM   5058 N N    . ALA A 1 322 ? 24.164  25.496  -19.594 1.000 17.081 0 337  ALA A N    1 ? 
ATOM   5059 C CA   . ALA A 1 322 ? 22.777  25.381  -19.109 1.000 15.906 0 337  ALA A CA   1 ? 
ATOM   5060 C C    . ALA A 1 322 ? 21.804  25.766  -20.222 1.000 15.493 0 337  ALA A C    1 ? 
ATOM   5061 O O    . ALA A 1 322 ? 20.845  25.020  -20.492 1.000 15.225 0 337  ALA A O    1 ? 
ATOM   5062 C CB   . ALA A 1 322 ? 22.538  26.212  -17.876 1.000 16.758 0 337  ALA A CB   1 ? 
ATOM   5063 H H    . ALA A 1 322 ? 24.721  26.112  -19.213 1.000 16.789 0 337  ALA A H    1 c 
ATOM   5064 H HA   . ALA A 1 322 ? 22.614  24.424  -18.881 1.000 16.206 0 337  ALA A HA   1 c 
ATOM   5065 H HB1  . ALA A 1 322 ? 23.132  25.919  -17.164 1.000 16.500 0 337  ALA A HB1  1 c 
ATOM   5066 H HB2  . ALA A 1 322 ? 22.711  27.148  -18.074 1.000 16.500 0 337  ALA A HB2  1 c 
ATOM   5067 H HB3  . ALA A 1 322 ? 21.616  26.111  -17.587 1.000 16.500 0 337  ALA A HB3  1 c 
ATOM   5068 N N    . LEU A 1 323 ? 22.067  26.917  -20.878 1.000 16.059 0 338  LEU A N    1 ? 
ATOM   5069 C CA   . LEU A 1 323 ? 21.213  27.314  -21.994 1.000 16.396 0 338  LEU A CA   1 ? 
ATOM   5070 C C    . LEU A 1 323 ? 21.207  26.254  -23.113 1.000 15.308 0 338  LEU A C    1 ? 
ATOM   5071 O O    . LEU A 1 323 ? 20.164  26.032  -23.725 1.000 16.095 0 338  LEU A O    1 ? 
ATOM   5072 C CB   . LEU A 1 323 ? 21.622  28.686  -22.545 1.000 17.050 0 338  LEU A CB   1 ? 
ATOM   5073 C CG   . LEU A 1 323 ? 21.359  29.873  -21.618 1.000 18.286 0 338  LEU A CG   1 ? 
ATOM   5074 C CD1  . LEU A 1 323 ? 22.102  31.093  -22.176 1.000 21.450 0 338  LEU A CD1  1 ? 
ATOM   5075 C CD2  . LEU A 1 323 ? 19.882  30.157  -21.553 1.000 19.494 0 338  LEU A CD2  1 ? 
ATOM   5076 H H    . LEU A 1 323 ? 22.767  27.450  -20.630 1.000 16.009 0 338  LEU A H    1 c 
ATOM   5077 H HA   . LEU A 1 323 ? 20.288  27.380  -21.648 1.000 16.260 0 338  LEU A HA   1 c 
ATOM   5078 H HB2  . LEU A 1 323 ? 22.585  28.659  -22.752 1.000 17.215 0 338  LEU A HB2  1 c 
ATOM   5079 H HB3  . LEU A 1 323 ? 21.137  28.837  -23.389 1.000 17.192 0 338  LEU A HB3  1 c 
ATOM   5080 H HG   . LEU A 1 323 ? 21.699  29.661  -20.710 1.000 18.813 0 338  LEU A HG   1 c 
ATOM   5081 H HD11 . LEU A 1 323 ? 23.058  30.913  -22.192 1.000 20.445 0 338  LEU A HD11 1 c 
ATOM   5082 H HD12 . LEU A 1 323 ? 21.928  31.865  -21.613 1.000 20.463 0 338  LEU A HD12 1 c 
ATOM   5083 H HD13 . LEU A 1 323 ? 21.794  31.276  -23.080 1.000 20.463 0 338  LEU A HD13 1 c 
ATOM   5084 H HD21 . LEU A 1 323 ? 19.423  29.407  -21.139 1.000 19.086 0 338  LEU A HD21 1 c 
ATOM   5085 H HD22 . LEU A 1 323 ? 19.536  30.291  -22.452 1.000 19.103 0 338  LEU A HD22 1 c 
ATOM   5086 H HD23 . LEU A 1 323 ? 19.728  30.959  -21.026 1.000 19.114 0 338  LEU A HD23 1 c 
ATOM   5087 N N    . GLN A 1 324 ? 22.360  25.677  -23.444 1.000 15.285 0 339  GLN A N    1 ? 
ATOM   5088 C CA   . GLN A 1 324 ? 22.407  24.642  -24.448 1.000 16.474 0 339  GLN A CA   1 ? 
ATOM   5089 C C    . GLN A 1 324 ? 21.516  23.457  -24.065 1.000 16.975 0 339  GLN A C    1 ? 
ATOM   5090 O O    . GLN A 1 324 ? 20.825  22.892  -24.913 1.000 17.366 0 339  GLN A O    1 ? 
ATOM   5091 C CB   . GLN A 1 324 ? 23.830  24.167  -24.700 1.000 19.675 0 339  GLN A CB   1 ? 
ATOM   5092 C CG   . GLN A 1 324 ? 23.887  23.156  -25.822 1.000 23.060 0 339  GLN A CG   1 ? 
ATOM   5093 C CD   . GLN A 1 324 ? 25.293  22.921  -26.302 1.000 33.644 0 339  GLN A CD   1 ? 
ATOM   5094 O OE1  . GLN A 1 324 ? 25.588  22.978  -27.503 1.000 42.158 0 339  GLN A OE1  1 ? 
ATOM   5095 N NE2  . GLN A 1 324 ? 26.164  22.693  -25.345 1.000 37.580 0 339  GLN A NE2  1 ? 
ATOM   5096 H H    . GLN A 1 324 ? 23.135  25.939  -23.037 1.000 15.586 0 339  GLN A H    1 c 
ATOM   5097 H HA   . GLN A 1 324 ? 22.063  25.025  -25.295 1.000 16.897 0 339  GLN A HA   1 c 
ATOM   5098 H HB2  . GLN A 1 324 ? 24.392  24.937  -24.927 1.000 19.669 0 339  GLN A HB2  1 c 
ATOM   5099 H HB3  . GLN A 1 324 ? 24.184  23.763  -23.881 1.000 19.677 0 339  GLN A HB3  1 c 
ATOM   5100 H HG2  . GLN A 1 324 ? 23.511  22.304  -25.514 1.000 24.226 0 339  GLN A HG2  1 c 
ATOM   5101 H HG3  . GLN A 1 324 ? 23.341  23.472  -26.574 1.000 24.169 0 339  GLN A HG3  1 c 
ATOM   5102 H HE21 . GLN A 1 324 ? 25.923  22.234  -24.625 1.000 36.097 0 339  GLN A HE21 1 c 
ATOM   5103 H HE22 . GLN A 1 324 ? 26.994  22.994  -25.422 1.000 36.372 0 339  GLN A HE22 1 c 
ATOM   5104 N N    . ALA A 1 325 ? 21.593  23.024  -22.808 1.000 16.124 0 340  ALA A N    1 ? 
ATOM   5105 C CA   . ALA A 1 325 ? 20.822  21.873  -22.385 1.000 17.105 0 340  ALA A CA   1 ? 
ATOM   5106 C C    . ALA A 1 325 ? 19.322  22.182  -22.396 1.000 15.831 0 340  ALA A C    1 ? 
ATOM   5107 O O    . ALA A 1 325 ? 18.509  21.355  -22.771 1.000 15.773 0 340  ALA A O    1 ? 
ATOM   5108 C CB   . ALA A 1 325 ? 21.278  21.427  -21.036 1.000 16.214 0 340  ALA A CB   1 ? 
ATOM   5109 H H    . ALA A 1 325 ? 22.134  23.448  -22.206 1.000 16.530 0 340  ALA A H    1 c 
ATOM   5110 H HA   . ALA A 1 325 ? 20.987  21.137  -23.036 1.000 16.582 0 340  ALA A HA   1 c 
ATOM   5111 H HB1  . ALA A 1 325 ? 22.197  21.113  -21.088 1.000 16.475 0 340  ALA A HB1  1 c 
ATOM   5112 H HB2  . ALA A 1 325 ? 21.229  22.171  -20.412 1.000 16.475 0 340  ALA A HB2  1 c 
ATOM   5113 H HB3  . ALA A 1 325 ? 20.710  20.705  -20.720 1.000 16.472 0 340  ALA A HB3  1 c 
ATOM   5114 N N    . TRP A 1 326 ? 18.954  23.382  -21.975 1.000 15.874 0 341  TRP A N    1 ? 
ATOM   5115 C CA   . TRP A 1 326 ? 17.557  23.788  -22.080 1.000 14.993 0 341  TRP A CA   1 ? 
ATOM   5116 C C    . TRP A 1 326 ? 17.104  23.866  -23.532 1.000 15.218 0 341  TRP A C    1 ? 
ATOM   5117 O O    . TRP A 1 326 ? 15.961  23.491  -23.834 1.000 16.384 0 341  TRP A O    1 ? 
ATOM   5118 C CB   . TRP A 1 326 ? 17.282  25.082  -21.326 1.000 13.923 0 341  TRP A CB   1 ? 
ATOM   5119 C CG   . TRP A 1 326 ? 17.300  24.933  -19.836 1.000 14.712 0 341  TRP A CG   1 ? 
ATOM   5120 C CD1  . TRP A 1 326 ? 16.727  23.936  -19.105 1.000 15.419 0 341  TRP A CD1  1 ? 
ATOM   5121 C CD2  . TRP A 1 326 ? 17.913  25.821  -18.871 1.000 15.042 0 341  TRP A CD2  1 ? 
ATOM   5122 N NE1  . TRP A 1 326 ? 16.933  24.150  -17.783 1.000 16.202 0 341  TRP A NE1  1 ? 
ATOM   5123 C CE2  . TRP A 1 326 ? 17.662  25.277  -17.595 1.000 16.563 0 341  TRP A CE2  1 ? 
ATOM   5124 C CE3  . TRP A 1 326 ? 18.632  27.016  -18.962 1.000 15.630 0 341  TRP A CE3  1 ? 
ATOM   5125 C CZ2  . TRP A 1 326 ? 18.140  25.866  -16.426 1.000 17.796 0 341  TRP A CZ2  1 ? 
ATOM   5126 C CZ3  . TRP A 1 326 ? 19.083  27.618  -17.812 1.000 16.850 0 341  TRP A CZ3  1 ? 
ATOM   5127 C CH2  . TRP A 1 326 ? 18.860  27.036  -16.556 1.000 17.563 0 341  TRP A CH2  1 ? 
ATOM   5128 H H    . TRP A 1 326 ? 19.565  23.957  -21.612 1.000 15.662 0 341  TRP A H    1 c 
ATOM   5129 H HA   . TRP A 1 326 ? 17.015  23.077  -21.644 1.000 15.013 0 341  TRP A HA   1 c 
ATOM   5130 H HB2  . TRP A 1 326 ? 17.957  25.744  -21.587 1.000 14.342 0 341  TRP A HB2  1 c 
ATOM   5131 H HB3  . TRP A 1 326 ? 16.403  25.422  -21.600 1.000 14.346 0 341  TRP A HB3  1 c 
ATOM   5132 H HD1  . TRP A 1 326 ? 16.244  23.206  -19.458 1.000 15.432 0 341  TRP A HD1  1 c 
ATOM   5133 H HE1  . TRP A 1 326 ? 16.667  23.615  -17.146 1.000 16.084 0 341  TRP A HE1  1 c 
ATOM   5134 H HE3  . TRP A 1 326 ? 18.811  27.399  -19.803 1.000 15.797 0 341  TRP A HE3  1 c 
ATOM   5135 H HZ2  . TRP A 1 326 ? 17.961  25.491  -15.581 1.000 17.414 0 341  TRP A HZ2  1 c 
ATOM   5136 H HZ3  . TRP A 1 326 ? 19.591  28.410  -17.872 1.000 16.704 0 341  TRP A HZ3  1 c 
ATOM   5137 H HH2  . TRP A 1 326 ? 19.173  27.472  -15.783 1.000 17.413 0 341  TRP A HH2  1 c 
ATOM   5138 N N    . ALA A 1 327 ? 17.914  24.423  -24.414 1.000 14.343 0 342  ALA A N    1 ? 
ATOM   5139 C CA   . ALA A 1 327 ? 17.538  24.409  -25.834 1.000 15.947 0 342  ALA A CA   1 ? 
ATOM   5140 C C    . ALA A 1 327 ? 17.306  22.975  -26.320 1.000 16.664 0 342  ALA A C    1 ? 
ATOM   5141 O O    . ALA A 1 327 ? 16.387  22.693  -27.083 1.000 16.722 0 342  ALA A O    1 ? 
ATOM   5142 C CB   . ALA A 1 327 ? 18.608  25.070  -26.666 1.000 15.773 0 342  ALA A CB   1 ? 
ATOM   5143 H H    . ALA A 1 327 ? 18.696  24.818  -24.153 1.000 14.905 0 342  ALA A H    1 c 
ATOM   5144 H HA   . ALA A 1 327 ? 16.686  24.916  -25.937 1.000 15.722 0 342  ALA A HA   1 c 
ATOM   5145 H HB1  . ALA A 1 327 ? 18.782  25.963  -26.326 1.000 15.836 0 342  ALA A HB1  1 c 
ATOM   5146 H HB2  . ALA A 1 327 ? 19.426  24.546  -26.624 1.000 15.834 0 342  ALA A HB2  1 c 
ATOM   5147 H HB3  . ALA A 1 327 ? 18.313  25.130  -27.590 1.000 15.866 0 342  ALA A HB3  1 c 
ATOM   5148 N N    . ASP A 1 328 ? 18.107  22.018  -25.810 1.000 15.473 0 343  ASP A N    1 ? 
ATOM   5149 C CA   . ASP A 1 328 ? 17.903  20.611  -26.128 1.000 17.033 0 343  ASP A CA   1 ? 
ATOM   5150 C C    . ASP A 1 328 ? 16.590  20.062  -25.567 1.000 16.097 0 343  ASP A C    1 ? 
ATOM   5151 O O    . ASP A 1 328 ? 15.937  19.289  -26.266 1.000 18.002 0 343  ASP A O    1 ? 
ATOM   5152 C CB   . ASP A 1 328 ? 19.106  19.783  -25.709 1.000 18.889 0 343  ASP A CB   1 ? 
ATOM   5153 C CG   . ASP A 1 328 ? 20.353  20.003  -26.562 1.000 23.215 0 343  ASP A CG   1 ? 
ATOM   5154 O OD1  . ASP A 1 328 ? 20.255  20.605  -27.685 1.000 25.401 0 343  ASP A OD1  1 ? 
ATOM   5155 O OD2  . ASP A 1 328 ? 21.450  19.668  -26.057 1.000 24.151 0 343  ASP A OD2  1 ? 
ATOM   5156 H H    . ASP A 1 328 ? 18.801  22.252  -25.263 1.000 16.112 0 343  ASP A H    1 c 
ATOM   5157 H HA   . ASP A 1 328 ? 17.855  20.535  -27.108 1.000 16.946 0 343  ASP A HA   1 c 
ATOM   5158 H HB2  . ASP A 1 328 ? 19.332  19.991  -24.779 1.000 19.295 0 343  ASP A HB2  1 c 
ATOM   5159 H HB3  . ASP A 1 328 ? 18.869  18.834  -25.757 1.000 19.315 0 343  ASP A HB3  1 c 
ATOM   5160 N N    . THR A 1 329 ? 16.175  20.473  -24.357 1.000 14.662 0 344  THR A N    1 ? 
ATOM   5161 C CA   . THR A 1 329 ? 14.896  20.078  -23.790 1.000 15.934 0 344  THR A CA   1 ? 
ATOM   5162 C C    . THR A 1 329 ? 13.775  20.529  -24.725 1.000 16.847 0 344  THR A C    1 ? 
ATOM   5163 O O    . THR A 1 329 ? 12.839  19.775  -25.009 1.000 16.343 0 344  THR A O    1 ? 
ATOM   5164 C CB   . THR A 1 329 ? 14.599  20.554  -22.371 1.000 16.789 0 344  THR A CB   1 ? 
ATOM   5165 O OG1  . THR A 1 329 ? 14.410  21.963  -22.282 1.000 20.169 0 344  THR A OG1  1 ? 
ATOM   5166 C CG2  . THR A 1 329 ? 15.708  20.184  -21.404 1.000 17.862 0 344  THR A CG2  1 ? 
ATOM   5167 H H    . THR A 1 329 ? 16.716  21.027  -23.872 1.000 15.319 0 344  THR A H    1 c 
ATOM   5168 H HA   . THR A 1 329 ? 14.884  19.096  -23.771 1.000 16.005 0 344  THR A HA   1 c 
ATOM   5169 H HB   . THR A 1 329 ? 13.775  20.108  -22.064 1.000 17.438 0 344  THR A HB   1 c 
ATOM   5170 H HG1  . THR A 1 329 ? 15.125  22.368  -22.551 0.000 20.190 0 344  THR A HG1  1 c 
ATOM   5171 H HG21 . THR A 1 329 ? 15.627  20.723  -20.598 1.000 17.533 0 344  THR A HG21 1 c 
ATOM   5172 H HG22 . THR A 1 329 ? 16.571  20.346  -21.814 1.000 17.483 0 344  THR A HG22 1 c 
ATOM   5173 H HG23 . THR A 1 329 ? 15.631  19.244  -21.170 1.000 17.490 0 344  THR A HG23 1 c 
ATOM   5174 N N    . ALA A 1 330 ? 13.895  21.757  -25.245 1.000 16.373 0 345  ALA A N    1 ? 
ATOM   5175 C CA   . ALA A 1 330 ? 12.876  22.280  -26.145 1.000 16.473 0 345  ALA A CA   1 ? 
ATOM   5176 C C    . ALA A 1 330 ? 12.870  21.580  -27.506 1.000 16.126 0 345  ALA A C    1 ? 
ATOM   5177 O O    . ALA A 1 330 ? 11.811  21.437  -28.104 1.000 17.209 0 345  ALA A O    1 ? 
ATOM   5178 C CB   . ALA A 1 330 ? 13.068  23.795  -26.274 1.000 17.046 0 345  ALA A CB   1 ? 
ATOM   5179 H H    . ALA A 1 330 ? 14.615  22.278  -25.034 1.000 16.494 0 345  ALA A H    1 c 
ATOM   5180 H HA   . ALA A 1 330 ? 11.990  22.116  -25.720 1.000 16.495 0 345  ALA A HA   1 c 
ATOM   5181 H HB1  . ALA A 1 330 ? 13.099  24.197  -25.389 1.000 16.870 0 345  ALA A HB1  1 c 
ATOM   5182 H HB2  . ALA A 1 330 ? 13.900  23.980  -26.741 1.000 16.856 0 345  ALA A HB2  1 c 
ATOM   5183 H HB3  . ALA A 1 330 ? 12.327  24.178  -26.773 1.000 16.862 0 345  ALA A HB3  1 c 
ATOM   5184 N N    . THR A 1 331 ? 14.038  21.156  -27.988 1.000 16.601 0 346  THR A N    1 ? 
ATOM   5185 C CA   . THR A 1 331 ? 14.118  20.456  -29.267 1.000 17.758 0 346  THR A CA   1 ? 
ATOM   5186 C C    . THR A 1 331 ? 13.453  19.084  -29.131 1.000 17.595 0 346  THR A C    1 ? 
ATOM   5187 O O    . THR A 1 331 ? 12.889  18.552  -30.080 1.000 19.475 0 346  THR A O    1 ? 
ATOM   5188 C CB   . THR A 1 331 ? 15.596  20.392  -29.674 1.000 18.887 0 346  THR A CB   1 ? 
ATOM   5189 O OG1  . THR A 1 331 ? 15.955  21.737  -30.001 1.000 19.971 0 346  THR A OG1  1 ? 
ATOM   5190 C CG2  . THR A 1 331 ? 15.835  19.469  -30.854 1.000 21.526 0 346  THR A CG2  1 ? 
ATOM   5191 H H    . THR A 1 331 ? 14.806  21.310  -27.517 1.000 16.763 0 346  THR A H    1 c 
ATOM   5192 H HA   . THR A 1 331 ? 13.630  20.979  -29.939 1.000 17.697 0 346  THR A HA   1 c 
ATOM   5193 H HB   . THR A 1 331 ? 16.139  20.085  -28.910 1.000 19.325 0 346  THR A HB   1 c 
ATOM   5194 H HG1  . THR A 1 331 ? 15.460  22.025  -30.648 0.000 19.960 0 346  THR A HG1  1 c 
ATOM   5195 H HG21 . THR A 1 331 ? 16.739  19.599  -31.189 1.000 20.704 0 346  THR A HG21 1 c 
ATOM   5196 H HG22 . THR A 1 331 ? 15.197  19.671  -31.559 1.000 20.705 0 346  THR A HG22 1 c 
ATOM   5197 H HG23 . THR A 1 331 ? 15.726  18.544  -30.573 1.000 20.692 0 346  THR A HG23 1 c 
ATOM   5198 N N    . VAL A 1 332 ? 13.415  18.484  -27.928 1.000 16.618 0 347  VAL A N    1 ? 
ATOM   5199 C CA   . VAL A 1 332 ? 12.605  17.276  -27.744 1.000 16.673 0 347  VAL A CA   1 ? 
ATOM   5200 C C    . VAL A 1 332 ? 11.101  17.593  -27.692 1.000 16.433 0 347  VAL A C    1 ? 
ATOM   5201 O O    . VAL A 1 332 ? 10.287  16.909  -28.350 1.000 17.160 0 347  VAL A O    1 ? 
ATOM   5202 C CB   . VAL A 1 332 ? 13.055  16.508  -26.483 1.000 16.125 0 347  VAL A CB   1 ? 
ATOM   5203 C CG1  . VAL A 1 332 ? 12.154  15.277  -26.230 1.000 18.047 0 347  VAL A CG1  1 ? 
ATOM   5204 C CG2  . VAL A 1 332 ? 14.528  16.173  -26.561 1.000 18.362 0 347  VAL A CG2  1 ? 
ATOM   5205 H H    . VAL A 1 332 ? 13.887  18.823  -27.223 1.000 16.867 0 347  VAL A H    1 c 
ATOM   5206 H HA   . VAL A 1 332 ? 12.760  16.694  -28.513 1.000 16.538 0 347  VAL A HA   1 c 
ATOM   5207 H HB   . VAL A 1 332 ? 12.937  17.121  -25.721 1.000 17.028 0 347  VAL A HB   1 c 
ATOM   5208 H HG11 . VAL A 1 332 ? 12.057  14.770  -27.054 1.000 17.471 0 347  VAL A HG11 1 c 
ATOM   5209 H HG12 . VAL A 1 332 ? 11.279  15.568  -25.925 1.000 17.487 0 347  VAL A HG12 1 c 
ATOM   5210 H HG13 . VAL A 1 332 ? 12.560  14.713  -25.550 1.000 17.471 0 347  VAL A HG13 1 c 
ATOM   5211 H HG21 . VAL A 1 332 ? 14.772  15.610  -25.807 1.000 17.665 0 347  VAL A HG21 1 c 
ATOM   5212 H HG22 . VAL A 1 332 ? 15.052  16.989  -26.536 1.000 17.658 0 347  VAL A HG22 1 c 
ATOM   5213 H HG23 . VAL A 1 332 ? 14.709  15.698  -27.390 1.000 17.666 0 347  VAL A HG23 1 c 
ATOM   5214 N N    . ILE A 1 333 ? 10.672  18.576  -26.874 1.000 14.928 0 348  ILE A N    1 ? 
ATOM   5215 C CA   . ILE A 1 333 ? 9.277   18.821  -26.634 1.000 14.893 0 348  ILE A CA   1 ? 
ATOM   5216 C C    . ILE A 1 333 ? 8.581   19.257  -27.928 1.000 16.921 0 348  ILE A C    1 ? 
ATOM   5217 O O    . ILE A 1 333 ? 7.362   19.097  -28.022 1.000 16.697 0 348  ILE A O    1 ? 
ATOM   5218 C CB   . ILE A 1 333 ? 9.030   19.794  -25.466 1.000 15.897 0 348  ILE A CB   1 ? 
ATOM   5219 C CG1  . ILE A 1 333 ? 7.627   19.564  -24.822 1.000 16.358 0 348  ILE A CG1  1 ? 
ATOM   5220 C CG2  . ILE A 1 333 ? 9.226   21.258  -25.880 1.000 16.912 0 348  ILE A CG2  1 ? 
ATOM   5221 C CD1  . ILE A 1 333 ? 7.458   18.218  -24.141 1.000 16.654 0 348  ILE A CD1  1 ? 
ATOM   5222 H H    . ILE A 1 333 ? 11.288  19.106  -26.456 1.000 15.290 0 348  ILE A H    1 c 
ATOM   5223 H HA   . ILE A 1 333 ? 8.886   17.967  -26.377 1.000 15.479 0 348  ILE A HA   1 c 
ATOM   5224 H HB   . ILE A 1 333 ? 9.697   19.594  -24.779 1.000 15.967 0 348  ILE A HB   1 c 
ATOM   5225 H HG12 . ILE A 1 333 ? 7.467   20.270  -24.163 1.000 16.325 0 348  ILE A HG12 1 c 
ATOM   5226 H HG13 . ILE A 1 333 ? 6.947   19.648  -25.520 1.000 16.340 0 348  ILE A HG13 1 c 
ATOM   5227 H HG21 . ILE A 1 333 ? 9.321   21.811  -25.086 1.000 16.609 0 348  ILE A HG21 1 c 
ATOM   5228 H HG22 . ILE A 1 333 ? 8.457   21.559  -26.392 1.000 16.611 0 348  ILE A HG22 1 c 
ATOM   5229 H HG23 . ILE A 1 333 ? 10.026  21.337  -26.424 1.000 16.611 0 348  ILE A HG23 1 c 
ATOM   5230 H HD11 . ILE A 1 333 ? 7.442   17.506  -24.808 1.000 16.549 0 348  ILE A HD11 1 c 
ATOM   5231 H HD12 . ILE A 1 333 ? 6.619   18.212  -23.642 1.000 16.562 0 348  ILE A HD12 1 c 
ATOM   5232 H HD13 . ILE A 1 333 ? 8.201   18.068  -23.525 1.000 16.562 0 348  ILE A HD13 1 c 
ATOM   5233 N N    . GLN A 1 334 ? 9.330   19.840  -28.873 1.000 16.128 0 349  GLN A N    1 ? 
ATOM   5234 C CA   . GLN A 1 334 ? 8.675   20.442  -30.043 1.000 17.738 0 349  GLN A CA   1 ? 
ATOM   5235 C C    . GLN A 1 334 ? 7.894   19.419  -30.863 1.000 18.839 0 349  GLN A C    1 ? 
ATOM   5236 O O    . GLN A 1 334 ? 6.972   19.857  -31.577 1.000 19.020 0 349  GLN A O    1 ? 
ATOM   5237 C CB   . GLN A 1 334 ? 9.698   21.183  -30.887 1.000 18.261 0 349  GLN A CB   1 ? 
ATOM   5238 C CG   . GLN A 1 334 ? 10.598  20.281  -31.688 1.000 18.941 0 349  GLN A CG   1 ? 
ATOM   5239 C CD   . GLN A 1 334 ? 11.591  21.088  -32.497 1.000 25.296 0 349  GLN A CD   1 ? 
ATOM   5240 O OE1  . GLN A 1 334 ? 11.354  22.244  -32.827 1.000 29.835 0 349  GLN A OE1  1 ? 
ATOM   5241 N NE2  . GLN A 1 334 ? 12.731  20.493  -32.748 1.000 29.429 0 349  GLN A NE2  1 ? 
ATOM   5242 H H    . GLN A 1 334 ? 10.239  19.883  -28.795 1.000 16.657 0 349  GLN A H    1 c 
ATOM   5243 H HA   . GLN A 1 334 ? 8.029   21.115  -29.709 1.000 17.694 0 349  GLN A HA   1 c 
ATOM   5244 H HB2  . GLN A 1 334 ? 9.222   21.775  -31.499 1.000 18.337 0 349  GLN A HB2  1 c 
ATOM   5245 H HB3  . GLN A 1 334 ? 10.248  21.741  -30.299 1.000 18.286 0 349  GLN A HB3  1 c 
ATOM   5246 H HG2  . GLN A 1 334 ? 11.079  19.679  -31.084 1.000 20.158 0 349  GLN A HG2  1 c 
ATOM   5247 H HG3  . GLN A 1 334 ? 10.060  19.733  -32.298 1.000 20.086 0 349  GLN A HG3  1 c 
ATOM   5248 H HE21 . GLN A 1 334 ? 12.811  19.615  -32.639 1.000 27.930 0 349  GLN A HE21 1 c 
ATOM   5249 H HE22 . GLN A 1 334 ? 13.425  20.970  -33.029 1.000 28.064 0 349  GLN A HE22 1 c 
ATOM   5250 N N    . ASP A 1 335 ? 8.259   18.118  -30.793 1.000 17.581 0 350  ASP A N    1 ? 
ATOM   5251 C CA   . ASP A 1 335 ? 7.592   17.070  -31.553 1.000 17.366 0 350  ASP A CA   1 ? 
ATOM   5252 C C    . ASP A 1 335 ? 6.556   16.323  -30.742 1.000 19.872 0 350  ASP A C    1 ? 
ATOM   5253 O O    . ASP A 1 335 ? 6.217   15.190  -31.072 1.000 23.683 0 350  ASP A O    1 ? 
ATOM   5254 C CB   . ASP A 1 335 ? 8.609   16.149  -32.207 1.000 20.410 0 350  ASP A CB   1 ? 
ATOM   5255 C CG   . ASP A 1 335 ? 9.427   16.845  -33.283 1.000 26.334 0 350  ASP A CG   1 ? 
ATOM   5256 O OD1  . ASP A 1 335 ? 8.797   17.498  -34.157 1.000 29.017 0 350  ASP A OD1  1 ? 
ATOM   5257 O OD2  . ASP A 1 335 ? 10.651  16.749  -33.226 1.000 29.786 0 350  ASP A OD2  1 ? 
ATOM   5258 H H    . ASP A 1 335 ? 8.963   17.883  -30.260 1.000 17.804 0 350  ASP A H    1 c 
ATOM   5259 H HA   . ASP A 1 335 ? 7.118   17.502  -32.298 1.000 18.492 0 350  ASP A HA   1 c 
ATOM   5260 H HB2  . ASP A 1 335 ? 9.219   15.805  -31.522 1.000 20.941 0 350  ASP A HB2  1 c 
ATOM   5261 H HB3  . ASP A 1 335 ? 8.150   15.388  -32.618 1.000 20.896 0 350  ASP A HB3  1 c 
ATOM   5262 N N    . TYR A 1 336 ? 5.980   16.975  -29.749 1.000 16.862 0 351  TYR A N    1 ? 
ATOM   5263 C CA   . TYR A 1 336 ? 4.832   16.516  -28.995 1.000 16.707 0 351  TYR A CA   1 ? 
ATOM   5264 C C    . TYR A 1 336 ? 3.675   17.477  -29.206 1.000 18.670 0 351  TYR A C    1 ? 
ATOM   5265 O O    . TYR A 1 336 ? 3.884   18.595  -29.688 1.000 20.163 0 351  TYR A O    1 ? 
ATOM   5266 C CB   . TYR A 1 336 ? 5.128   16.479  -27.493 1.000 18.118 0 351  TYR A CB   1 ? 
ATOM   5267 C CG   . TYR A 1 336 ? 5.975   15.284  -27.079 1.000 16.573 0 351  TYR A CG   1 ? 
ATOM   5268 C CD1  . TYR A 1 336 ? 5.354   14.095  -26.747 1.000 16.263 0 351  TYR A CD1  1 ? 
ATOM   5269 C CD2  . TYR A 1 336 ? 7.358   15.317  -27.001 1.000 15.852 0 351  TYR A CD2  1 ? 
ATOM   5270 C CE1  . TYR A 1 336 ? 6.074   12.978  -26.385 1.000 15.560 0 351  TYR A CE1  1 ? 
ATOM   5271 C CE2  . TYR A 1 336 ? 8.089   14.203  -26.628 1.000 16.698 0 351  TYR A CE2  1 ? 
ATOM   5272 C CZ   . TYR A 1 336 ? 7.444   13.019  -26.310 1.000 15.182 0 351  TYR A CZ   1 ? 
ATOM   5273 O OH   . TYR A 1 336 ? 8.125   11.902  -25.900 1.000 16.841 0 351  TYR A OH   1 ? 
ATOM   5274 H H    . TYR A 1 336 ? 6.336   17.782  -29.511 1.000 17.503 0 351  TYR A H    1 c 
ATOM   5275 H HA   . TYR A 1 336 ? 4.571   15.608  -29.304 1.000 17.390 0 351  TYR A HA   1 c 
ATOM   5276 H HB2  . TYR A 1 336 ? 5.597   17.306  -27.244 1.000 17.429 0 351  TYR A HB2  1 c 
ATOM   5277 H HB3  . TYR A 1 336 ? 4.276   16.451  -27.003 1.000 17.442 0 351  TYR A HB3  1 c 
ATOM   5278 H HD1  . TYR A 1 336 ? 4.414   14.039  -26.796 1.000 16.181 0 351  TYR A HD1  1 c 
ATOM   5279 H HD2  . TYR A 1 336 ? 7.814   16.114  -27.220 1.000 16.210 0 351  TYR A HD2  1 c 
ATOM   5280 H HE1  . TYR A 1 336 ? 5.620   12.184  -26.158 1.000 15.642 0 351  TYR A HE1  1 c 
ATOM   5281 H HE2  . TYR A 1 336 ? 9.029   14.252  -26.578 1.000 16.144 0 351  TYR A HE2  1 c 
ATOM   5282 H HH   . TYR A 1 336 ? 8.322   11.414  -26.578 0.000 16.830 0 351  TYR A HH   1 c 
ATOM   5283 N N    . ASN A 1 337 ? 2.464   16.992  -28.927 1.000 18.514 0 352  ASN A N    1 ? 
ATOM   5284 C CA   . ASN A 1 337 ? 1.285   17.818  -28.731 1.000 21.254 0 352  ASN A CA   1 ? 
ATOM   5285 C C    . ASN A 1 337 ? 1.079   18.045  -27.248 1.000 21.818 0 352  ASN A C    1 ? 
ATOM   5286 O O    . ASN A 1 337 ? 1.148   17.074  -26.482 1.000 23.729 0 352  ASN A O    1 ? 
ATOM   5287 C CB   . ASN A 1 337 ? 0.038   17.152  -29.294 1.000 24.319 0 352  ASN A CB   1 ? 
ATOM   5288 C CG   . ASN A 1 337 ? 0.007   17.132  -30.797 1.000 28.904 0 352  ASN A CG   1 ? 
ATOM   5289 O OD1  . ASN A 1 337 ? 0.607   18.002  -31.440 1.000 32.206 0 352  ASN A OD1  1 ? 
ATOM   5290 N ND2  . ASN A 1 337 ? -0.569  16.071  -31.346 1.000 33.102 0 352  ASN A ND2  1 ? 
ATOM   5291 H H    . ASN A 1 337 ? 2.368   16.086  -28.854 1.000 19.176 0 352  ASN A H    1 c 
ATOM   5292 H HA   . ASN A 1 337 ? 1.411   18.681  -29.186 1.000 21.370 0 352  ASN A HA   1 c 
ATOM   5293 H HB2  . ASN A 1 337 ? -0.008  16.234  -28.961 1.000 24.592 0 352  ASN A HB2  1 c 
ATOM   5294 H HB3  . ASN A 1 337 ? -0.752  17.628  -28.968 1.000 24.541 0 352  ASN A HB3  1 c 
ATOM   5295 H HD21 . ASN A 1 337 ? -1.107  15.554  -30.864 1.000 31.617 0 352  ASN A HD21 1 c 
ATOM   5296 H HD22 . ASN A 1 337 ? -0.417  15.880  -32.199 1.000 31.717 0 352  ASN A HD22 1 c 
ATOM   5297 N N    . TYR A 1 338 ? 0.809   19.304  -26.845 1.000 20.482 0 353  TYR A N    1 ? 
ATOM   5298 C CA   . TYR A 1 338 ? 0.551   19.660  -25.457 1.000 21.463 0 353  TYR A CA   1 ? 
ATOM   5299 C C    . TYR A 1 338 ? -0.882  19.263  -25.115 1.000 20.337 0 353  TYR A C    1 ? 
ATOM   5300 O O    . TYR A 1 338 ? -1.807  19.811  -25.683 1.000 22.967 0 353  TYR A O    1 ? 
ATOM   5301 C CB   . TYR A 1 338 ? 0.778   21.154  -25.111 1.000 22.524 0 353  TYR A CB   1 ? 
ATOM   5302 C CG   . TYR A 1 338 ? 0.533   21.530  -23.653 1.000 22.098 0 353  TYR A CG   1 ? 
ATOM   5303 C CD1  . TYR A 1 338 ? 1.015   20.749  -22.605 1.000 21.869 0 353  TYR A CD1  1 ? 
ATOM   5304 C CD2  . TYR A 1 338 ? -0.215  22.647  -23.290 1.000 26.545 0 353  TYR A CD2  1 ? 
ATOM   5305 C CE1  . TYR A 1 338 ? 0.781   21.054  -21.278 1.000 20.882 0 353  TYR A CE1  1 ? 
ATOM   5306 C CE2  . TYR A 1 338 ? -0.436  22.985  -21.966 1.000 26.020 0 353  TYR A CE2  1 ? 
ATOM   5307 C CZ   . TYR A 1 338 ? 0.051   22.179  -20.950 1.000 25.034 0 353  TYR A CZ   1 ? 
ATOM   5308 O OH   . TYR A 1 338 ? -0.174  22.456  -19.630 1.000 26.124 0 353  TYR A OH   1 ? 
ATOM   5309 H H    . TYR A 1 338 ? 0.796   19.970  -27.470 1.000 21.044 0 353  TYR A H    1 c 
ATOM   5310 H HA   . TYR A 1 338 ? 1.163   19.122  -24.891 1.000 21.261 0 353  TYR A HA   1 c 
ATOM   5311 H HB2  . TYR A 1 338 ? 1.704   21.387  -25.345 1.000 22.184 0 353  TYR A HB2  1 c 
ATOM   5312 H HB3  . TYR A 1 338 ? 0.186   21.695  -25.679 1.000 22.184 0 353  TYR A HB3  1 c 
ATOM   5313 H HD1  . TYR A 1 338 ? 1.513   19.973  -22.808 1.000 21.756 0 353  TYR A HD1  1 c 
ATOM   5314 H HD2  . TYR A 1 338 ? -0.558  23.209  -23.967 1.000 25.261 0 353  TYR A HD2  1 c 
ATOM   5315 H HE1  . TYR A 1 338 ? 1.125   20.502  -20.598 1.000 22.085 0 353  TYR A HE1  1 c 
ATOM   5316 H HE2  . TYR A 1 338 ? -0.949  23.746  -21.755 1.000 25.824 0 353  TYR A HE2  1 c 
ATOM   5317 H HH   . TYR A 1 338 ? 0.459   22.944  -19.319 0.000 26.130 0 353  TYR A HH   1 c 
ATOM   5318 N N    . CYS A 1 339 ? -1.051  18.241  -24.285 1.000 19.934 0 354  CYS A N    1 ? 
ATOM   5319 C CA   . CYS A 1 339 ? -2.348  17.662  -23.971 1.000 24.449 0 354  CYS A CA   1 ? 
ATOM   5320 C C    . CYS A 1 339 ? -2.702  17.873  -22.489 1.000 25.197 0 354  CYS A C    1 ? 
ATOM   5321 O O    . CYS A 1 339 ? -1.860  18.219  -21.657 1.000 25.468 0 354  CYS A O    1 ? 
ATOM   5322 C CB   . CYS A 1 339 ? -2.378  16.190  -24.386 1.000 24.979 0 354  CYS A CB   1 ? 
ATOM   5323 S SG   . CYS A 1 339 ? -2.103  15.864  -26.158 1.000 23.824 0 354  CYS A SG   1 ? 
ATOM   5324 H H    . CYS A 1 339 ? -0.312  17.879  -23.886 1.000 20.986 0 354  CYS A H    1 c 
ATOM   5325 H HA   . CYS A 1 339 ? -3.030  18.131  -24.515 1.000 23.690 0 354  CYS A HA   1 c 
ATOM   5326 H HB2  . CYS A 1 339 ? -1.690  15.706  -23.877 1.000 24.635 0 354  CYS A HB2  1 c 
ATOM   5327 H HB3  . CYS A 1 339 ? -3.250  15.811  -24.139 1.000 24.655 0 354  CYS A HB3  1 c 
ATOM   5328 H HG   . CYS A 1 339 ? -2.197  14.656  -26.115 0.000 23.830 0 354  CYS A HG   1 c 
ATOM   5329 N N    . ARG A 1 340 ? -3.973  17.598  -22.147 1.000 28.072 0 355  ARG A N    1 ? 
ATOM   5330 C CA   . ARG A 1 340 ? -4.569  17.947  -20.861 1.000 31.761 0 355  ARG A CA   1 ? 
ATOM   5331 C C    . ARG A 1 340 ? -3.858  17.399  -19.610 1.000 34.227 0 355  ARG A C    1 ? 
ATOM   5332 O O    . ARG A 1 340 ? -3.933  17.980  -18.533 1.000 42.360 0 355  ARG A O    1 ? 
ATOM   5333 C CB   . ARG A 1 340 ? -6.022  17.446  -20.836 1.000 37.626 0 355  ARG A CB   1 ? 
ATOM   5334 C CG   . ARG A 1 340 ? -6.823  17.968  -19.647 1.000 52.549 0 355  ARG A CG   1 ? 
ATOM   5335 C CD   . ARG A 1 340 ? -8.210  17.328  -19.553 1.000 67.008 0 355  ARG A CD   1 ? 
ATOM   5336 N NE   . ARG A 1 340 ? -8.942  17.791  -18.365 1.000 79.503 0 355  ARG A NE   1 ? 
ATOM   5337 C CZ   . ARG A 1 340 ? -9.895  17.120  -17.708 1.000 86.927 0 355  ARG A CZ   1 ? 
ATOM   5338 N NH1  . ARG A 1 340 ? -10.208 15.881  -18.049 1.000 86.007 0 355  ARG A NH1  1 ? 
ATOM   5339 N NH2  . ARG A 1 340 ? -10.516 17.681  -16.681 1.000 89.553 0 355  ARG A NH2  1 ? 
ATOM   5340 H H    . ARG A 1 340 ? -4.498  17.166  -22.759 1.000 28.191 0 355  ARG A H    1 c 
ATOM   5341 H HA   . ARG A 1 340 ? -4.586  18.936  -20.795 1.000 32.417 0 355  ARG A HA   1 c 
ATOM   5342 H HB2  . ARG A 1 340 ? -6.468  17.724  -21.665 1.000 39.014 0 355  ARG A HB2  1 c 
ATOM   5343 H HB3  . ARG A 1 340 ? -6.019  16.466  -20.811 1.000 39.061 0 355  ARG A HB3  1 c 
ATOM   5344 H HG2  . ARG A 1 340 ? -6.335  17.784  -18.817 1.000 51.293 0 355  ARG A HG2  1 c 
ATOM   5345 H HG3  . ARG A 1 340 ? -6.925  18.941  -19.729 1.000 51.418 0 355  ARG A HG3  1 c 
ATOM   5346 H HD2  . ARG A 1 340 ? -8.725  17.551  -20.356 1.000 66.100 0 355  ARG A HD2  1 c 
ATOM   5347 H HD3  . ARG A 1 340 ? -8.112  16.355  -19.516 1.000 66.261 0 355  ARG A HD3  1 c 
ATOM   5348 H HE   . ARG A 1 340 ? -8.735  18.578  -18.055 1.000 77.992 0 355  ARG A HE   1 c 
ATOM   5349 H HH11 . ARG A 1 340 ? -10.344 15.275  -17.408 1.000 86.253 0 355  ARG A HH11 1 c 
ATOM   5350 H HH12 . ARG A 1 340 ? -10.287 15.663  -18.911 1.000 85.961 0 355  ARG A HH12 1 c 
ATOM   5351 H HH21 . ARG A 1 340 ? -11.164 17.243  -16.267 1.000 88.655 0 355  ARG A HH21 1 c 
ATOM   5352 H HH22 . ARG A 1 340 ? -10.284 18.490  -16.410 1.000 88.554 0 355  ARG A HH22 1 c 
ATOM   5353 N N    . GLU A 1 341 ? -3.169  16.293  -19.711 1.000 26.775 0 356  GLU A N    1 ? 
ATOM   5354 C CA   . GLU A 1 341 ? -2.527  15.715  -18.532 1.000 22.401 0 356  GLU A CA   1 ? 
ATOM   5355 C C    . GLU A 1 341 ? -1.006  15.881  -18.549 1.000 20.996 0 356  GLU A C    1 ? 
ATOM   5356 O O    . GLU A 1 341 ? -0.313  15.200  -17.780 1.000 18.665 0 356  GLU A O    1 ? 
ATOM   5357 C CB   . GLU A 1 341 ? -2.868  14.231  -18.446 1.000 26.712 0 356  GLU A CB   1 ? 
ATOM   5358 C CG   . GLU A 1 341 ? -4.349  13.986  -18.195 1.000 32.523 0 356  GLU A CG   1 ? 
ATOM   5359 C CD   . GLU A 1 341 ? -4.616  12.603  -17.624 1.000 38.325 0 356  GLU A CD   1 ? 
ATOM   5360 O OE1  . GLU A 1 341 ? -5.157  11.858  -18.436 1.000 44.530 0 356  GLU A OE1  1 ? 
ATOM   5361 O OE2  . GLU A 1 341 ? -4.208  12.250  -16.477 1.000 39.082 0 356  GLU A OE2  1 ? 
ATOM   5362 H H    . GLU A 1 341 ? -3.091  15.869  -20.517 1.000 27.309 0 356  GLU A H    1 c 
ATOM   5363 H HA   . GLU A 1 341 ? -2.885  16.158  -17.725 1.000 23.858 0 356  GLU A HA   1 c 
ATOM   5364 H HB2  . GLU A 1 341 ? -2.604  13.792  -19.280 1.000 26.821 0 356  GLU A HB2  1 c 
ATOM   5365 H HB3  . GLU A 1 341 ? -2.353  13.826  -17.718 1.000 26.757 0 356  GLU A HB3  1 c 
ATOM   5366 H HG2  . GLU A 1 341 ? -4.688  14.658  -17.566 1.000 32.174 0 356  GLU A HG2  1 c 
ATOM   5367 H HG3  . GLU A 1 341 ? -4.842  14.082  -19.038 1.000 32.336 0 356  GLU A HG3  1 c 
ATOM   5368 N N    . ASP A 1 342 ? -0.515  16.802  -19.375 1.000 17.160 0 357  ASP A N    1 ? 
ATOM   5369 C CA   . ASP A 1 342 ? 0.923   17.065  -19.481 1.000 16.485 0 357  ASP A CA   1 ? 
ATOM   5370 C C    . ASP A 1 342 ? 1.381   18.235  -18.582 1.000 17.061 0 357  ASP A C    1 ? 
ATOM   5371 O O    . ASP A 1 342 ? 2.484   18.766  -18.744 1.000 16.484 0 357  ASP A O    1 ? 
ATOM   5372 C CB   . ASP A 1 342 ? 1.315   17.330  -20.935 1.000 16.899 0 357  ASP A CB   1 ? 
ATOM   5373 C CG   . ASP A 1 342 ? 1.259   16.159  -21.893 1.000 20.084 0 357  ASP A CG   1 ? 
ATOM   5374 O OD1  . ASP A 1 342 ? 1.122   15.034  -21.395 1.000 19.489 0 357  ASP A OD1  1 ? 
ATOM   5375 O OD2  . ASP A 1 342 ? 1.327   16.390  -23.111 1.000 18.305 0 357  ASP A OD2  1 ? 
ATOM   5376 H H    . ASP A 1 342 ? -1.086  17.292  -19.892 1.000 18.003 0 357  ASP A H    1 c 
ATOM   5377 H HA   . ASP A 1 342 ? 1.405   16.256  -19.197 1.000 16.840 0 357  ASP A HA   1 c 
ATOM   5378 H HB2  . ASP A 1 342 ? 0.732   18.034  -21.288 1.000 17.526 0 357  ASP A HB2  1 c 
ATOM   5379 H HB3  . ASP A 1 342 ? 2.233   17.673  -20.955 1.000 17.495 0 357  ASP A HB3  1 c 
ATOM   5380 N N    A GLU A 1 343 ? 0.553   18.652  -17.615 0.500 17.358 0 358  GLU A N    1 ? 
ATOM   5381 N N    B GLU A 1 343 ? 0.554   18.673  -17.624 0.500 18.216 0 358  GLU A N    1 ? 
ATOM   5382 C CA   A GLU A 1 343 ? 0.813   19.880  -16.863 0.500 18.937 0 358  GLU A CA   1 ? 
ATOM   5383 C CA   B GLU A 1 343 ? 0.829   19.913  -16.894 0.500 20.581 0 358  GLU A CA   1 ? 
ATOM   5384 C C    A GLU A 1 343 ? 2.167   19.880  -16.148 0.500 17.641 0 358  GLU A C    1 ? 
ATOM   5385 C C    B GLU A 1 343 ? 2.180   19.885  -16.168 0.500 18.436 0 358  GLU A C    1 ? 
ATOM   5386 O O    A GLU A 1 343 ? 2.753   20.942  -15.957 0.500 17.432 0 358  GLU A O    1 ? 
ATOM   5387 O O    B GLU A 1 343 ? 2.799   20.934  -16.015 0.500 17.882 0 358  GLU A O    1 ? 
ATOM   5388 C CB   A GLU A 1 343 ? -0.293  20.139  -15.834 0.500 20.405 0 358  GLU A CB   1 ? 
ATOM   5389 C CB   B GLU A 1 343 ? -0.334  20.232  -15.944 0.500 23.940 0 358  GLU A CB   1 ? 
ATOM   5390 C CG   A GLU A 1 343 ? -0.556  18.955  -14.901 0.500 24.699 0 358  GLU A CG   1 ? 
ATOM   5391 C CG   B GLU A 1 343 ? -0.253  21.594  -15.257 0.500 31.253 0 358  GLU A CG   1 ? 
ATOM   5392 C CD   A GLU A 1 343 ? -1.472  17.842  -15.438 0.500 26.444 0 358  GLU A CD   1 ? 
ATOM   5393 C CD   B GLU A 1 343 ? -1.235  21.838  -14.119 0.500 33.186 0 358  GLU A CD   1 ? 
ATOM   5394 O OE1  A GLU A 1 343 ? -2.041  18.058  -16.533 0.500 21.587 0 358  GLU A OE1  1 ? 
ATOM   5395 O OE1  B GLU A 1 343 ? -1.773  20.901  -13.488 0.500 35.250 0 358  GLU A OE1  1 ? 
ATOM   5396 O OE2  A GLU A 1 343 ? -1.615  16.764  -14.763 0.500 30.439 0 358  GLU A OE2  1 ? 
ATOM   5397 O OE2  B GLU A 1 343 ? -1.440  23.036  -13.855 0.500 41.993 0 358  GLU A OE2  1 ? 
ATOM   5398 H H    A GLU A 1 343 ? -0.188  18.160  -17.409 0.500 17.635 0 358  GLU A H    1 c 
ATOM   5399 H H    B GLU A 1 343 ? -0.193  18.192  -17.411 0.500 18.435 0 358  GLU A H    1 c 
ATOM   5400 H HA   A GLU A 1 343 ? 0.808   20.634  -17.506 0.500 18.632 0 358  GLU A HA   1 c 
ATOM   5401 H HA   B GLU A 1 343 ? 0.865   20.646  -17.560 0.500 20.255 0 358  GLU A HA   1 c 
ATOM   5402 H HB2  A GLU A 1 343 ? -0.044  20.919  -15.294 0.500 20.954 0 358  GLU A HB2  1 c 
ATOM   5403 H HB2  B GLU A 1 343 ? -1.172  20.189  -16.450 0.500 24.594 0 358  GLU A HB2  1 c 
ATOM   5404 H HB3  A GLU A 1 343 ? -1.121  20.358  -16.310 0.500 20.954 0 358  GLU A HB3  1 c 
ATOM   5405 H HB3  B GLU A 1 343 ? -0.370  19.539  -15.252 0.500 24.594 0 358  GLU A HB3  1 c 
ATOM   5406 H HG2  A GLU A 1 343 ? 0.303   18.550  -14.660 0.500 23.921 0 358  GLU A HG2  1 c 
ATOM   5407 H HG2  B GLU A 1 343 ? 0.655   21.713  -14.906 0.500 29.814 0 358  GLU A HG2  1 c 
ATOM   5408 H HG3  A GLU A 1 343 ? -0.951  19.296  -14.070 0.500 23.997 0 358  GLU A HG3  1 c 
ATOM   5409 H HG3  B GLU A 1 343 ? -0.392  22.293  -15.932 0.500 29.814 0 358  GLU A HG3  1 c 
ATOM   5410 N N    . GLU A 1 344 ? 2.679   18.711  -15.745 1.000 16.832 0 359  GLU A N    1 ? 
ATOM   5411 C CA   . GLU A 1 344 ? 3.949   18.656  -15.020 1.000 18.381 0 359  GLU A CA   1 ? 
ATOM   5412 C C    . GLU A 1 344 ? 5.103   19.190  -15.871 1.000 18.346 0 359  GLU A C    1 ? 
ATOM   5413 O O    . GLU A 1 344 ? 5.951   19.912  -15.345 1.000 17.898 0 359  GLU A O    1 ? 
ATOM   5414 C CB   . GLU A 1 344 ? 4.232   17.262  -14.466 1.000 21.850 0 359  GLU A CB   1 ? 
ATOM   5415 C CG   . GLU A 1 344 ? 3.256   16.941  -13.334 1.000 25.325 0 359  GLU A CG   1 ? 
ATOM   5416 C CD   . GLU A 1 344 ? 3.199   17.926  -12.181 1.000 32.212 0 359  GLU A CD   1 ? 
ATOM   5417 O OE1  . GLU A 1 344 ? 4.297   18.255  -11.680 1.000 29.115 0 359  GLU A OE1  1 ? 
ATOM   5418 O OE2  . GLU A 1 344 ? 2.067   18.389  -11.847 1.000 33.589 0 359  GLU A OE2  1 ? 
ATOM   5419 H H    . GLU A 1 344 ? 2.225   17.936  -15.910 1.000 17.623 0 359  GLU A H    1 c 
ATOM   5420 H HA   . GLU A 1 344 ? 3.865   19.259  -14.239 1.000 18.721 0 359  GLU A HA   1 c 
ATOM   5421 H HB2  . GLU A 1 344 ? 4.146   16.604  -15.187 1.000 21.695 0 359  GLU A HB2  1 c 
ATOM   5422 H HB3  . GLU A 1 344 ? 5.153   17.229  -14.134 1.000 21.693 0 359  GLU A HB3  1 c 
ATOM   5423 H HG2  . GLU A 1 344 ? 2.355   16.865  -13.713 1.000 25.894 0 359  GLU A HG2  1 c 
ATOM   5424 H HG3  . GLU A 1 344 ? 3.485   16.060  -12.968 1.000 25.893 0 359  GLU A HG3  1 c 
ATOM   5425 N N    . ILE A 1 345 ? 5.109   18.861  -17.162 1.000 16.146 0 360  ILE A N    1 ? 
ATOM   5426 C CA   . ILE A 1 345 ? 6.247   19.305  -17.979 1.000 16.778 0 360  ILE A CA   1 ? 
ATOM   5427 C C    . ILE A 1 345 ? 6.031   20.763  -18.405 1.000 16.195 0 360  ILE A C    1 ? 
ATOM   5428 O O    . ILE A 1 345 ? 7.013   21.505  -18.499 1.000 16.258 0 360  ILE A O    1 ? 
ATOM   5429 C CB   . ILE A 1 345 ? 6.553   18.379  -19.176 1.000 16.664 0 360  ILE A CB   1 ? 
ATOM   5430 C CG1  . ILE A 1 345 ? 8.057   18.469  -19.582 1.000 19.197 0 360  ILE A CG1  1 ? 
ATOM   5431 C CG2  . ILE A 1 345 ? 5.606   18.605  -20.335 1.000 17.905 0 360  ILE A CG2  1 ? 
ATOM   5432 C CD1  . ILE A 1 345 ? 8.994   17.979  -18.506 1.000 21.132 0 360  ILE A CD1  1 ? 
ATOM   5433 H H    . ILE A 1 345 ? 4.435   18.371  -17.537 1.000 16.800 0 360  ILE A H    1 c 
ATOM   5434 H HA   . ILE A 1 345 ? 7.032   19.290  -17.403 1.000 16.603 0 360  ILE A HA   1 c 
ATOM   5435 H HB   . ILE A 1 345 ? 6.405   17.465  -18.866 1.000 17.328 0 360  ILE A HB   1 c 
ATOM   5436 H HG12 . ILE A 1 345 ? 8.198   17.939  -20.392 1.000 19.021 0 360  ILE A HG12 1 c 
ATOM   5437 H HG13 . ILE A 1 345 ? 8.273   19.401  -19.790 1.000 19.021 0 360  ILE A HG13 1 c 
ATOM   5438 H HG21 . ILE A 1 345 ? 5.714   17.892  -20.987 1.000 17.525 0 360  ILE A HG21 1 c 
ATOM   5439 H HG22 . ILE A 1 345 ? 5.803   19.458  -20.758 1.000 17.519 0 360  ILE A HG22 1 c 
ATOM   5440 H HG23 . ILE A 1 345 ? 4.690   18.609  -20.012 1.000 17.520 0 360  ILE A HG23 1 c 
ATOM   5441 H HD11 . ILE A 1 345 ? 9.051   18.637  -17.788 1.000 20.477 0 360  ILE A HD11 1 c 
ATOM   5442 H HD12 . ILE A 1 345 ? 9.881   17.841  -18.889 1.000 20.510 0 360  ILE A HD12 1 c 
ATOM   5443 H HD13 . ILE A 1 345 ? 8.663   17.134  -18.145 1.000 20.492 0 360  ILE A HD13 1 c 
ATOM   5444 N N    . TYR A 1 346 ? 4.787   21.208  -18.549 1.000 15.810 0 361  TYR A N    1 ? 
ATOM   5445 C CA   . TYR A 1 346 ? 4.542   22.632  -18.725 1.000 15.197 0 361  TYR A CA   1 ? 
ATOM   5446 C C    . TYR A 1 346 ? 5.083   23.405  -17.533 1.000 15.039 0 361  TYR A C    1 ? 
ATOM   5447 O O    . TYR A 1 346 ? 5.701   24.438  -17.726 1.000 15.777 0 361  TYR A O    1 ? 
ATOM   5448 C CB   . TYR A 1 346 ? 3.050   22.902  -18.845 1.000 16.500 0 361  TYR A CB   1 ? 
ATOM   5449 C CG   . TYR A 1 346 ? 2.674   24.369  -18.913 1.000 16.038 0 361  TYR A CG   1 ? 
ATOM   5450 C CD1  . TYR A 1 346 ? 2.439   25.110  -17.753 1.000 18.405 0 361  TYR A CD1  1 ? 
ATOM   5451 C CD2  . TYR A 1 346 ? 2.616   25.030  -20.131 1.000 18.401 0 361  TYR A CD2  1 ? 
ATOM   5452 C CE1  . TYR A 1 346 ? 2.084   26.455  -17.835 1.000 18.534 0 361  TYR A CE1  1 ? 
ATOM   5453 C CE2  . TYR A 1 346 ? 2.302   26.379  -20.207 1.000 19.986 0 361  TYR A CE2  1 ? 
ATOM   5454 C CZ   . TYR A 1 346 ? 2.068   27.096  -19.047 1.000 17.564 0 361  TYR A CZ   1 ? 
ATOM   5455 O OH   . TYR A 1 346 ? 1.763   28.444  -19.054 1.000 20.611 0 361  TYR A OH   1 ? 
ATOM   5456 H H    . TYR A 1 346 ? 4.081   20.626  -18.549 1.000 15.769 0 361  TYR A H    1 c 
ATOM   5457 H HA   . TYR A 1 346 ? 4.998   22.942  -19.551 1.000 15.550 0 361  TYR A HA   1 c 
ATOM   5458 H HB2  . TYR A 1 346 ? 2.718   22.453  -19.653 1.000 16.109 0 361  TYR A HB2  1 c 
ATOM   5459 H HB3  . TYR A 1 346 ? 2.598   22.497  -18.073 1.000 16.107 0 361  TYR A HB3  1 c 
ATOM   5460 H HD1  . TYR A 1 346 ? 2.464   24.683  -16.911 1.000 17.869 0 361  TYR A HD1  1 c 
ATOM   5461 H HD2  . TYR A 1 346 ? 2.797   24.553  -20.925 1.000 18.168 0 361  TYR A HD2  1 c 
ATOM   5462 H HE1  . TYR A 1 346 ? 1.941   26.949  -17.046 1.000 18.279 0 361  TYR A HE1  1 c 
ATOM   5463 H HE2  . TYR A 1 346 ? 2.274   26.811  -21.042 1.000 19.038 0 361  TYR A HE2  1 c 
ATOM   5464 H HH   . TYR A 1 346 ? 2.478   28.908  -18.974 0.000 20.560 0 361  TYR A HH   1 c 
ATOM   5465 N N    . LYS A 1 347 ? 4.904   22.874  -16.311 1.000 15.252 0 362  LYS A N    1 ? 
ATOM   5466 C CA   . LYS A 1 347 ? 5.380   23.588  -15.131 1.000 16.603 0 362  LYS A CA   1 ? 
ATOM   5467 C C    . LYS A 1 347 ? 6.896   23.737  -15.153 1.000 16.439 0 362  LYS A C    1 ? 
ATOM   5468 O O    . LYS A 1 347 ? 7.421   24.818  -14.781 1.000 17.521 0 362  LYS A O    1 ? 
ATOM   5469 C CB   . LYS A 1 347 ? 4.917   22.950  -13.818 1.000 20.039 0 362  LYS A CB   1 ? 
ATOM   5470 C CG   . LYS A 1 347 ? 3.425   23.187  -13.598 1.000 27.387 0 362  LYS A CG   1 ? 
ATOM   5471 C CD   . LYS A 1 347 ? 2.688   22.312  -12.573 1.000 36.305 0 362  LYS A CD   1 ? 
ATOM   5472 C CE   . LYS A 1 347 ? 3.067   22.578  -11.171 1.000 45.402 0 362  LYS A CE   1 ? 
ATOM   5473 N NZ   . LYS A 1 347 ? 4.466   22.241  -10.883 1.000 51.683 0 362  LYS A NZ   1 ? 
ATOM   5474 H H    . LYS A 1 347 ? 4.480   22.070  -16.209 1.000 15.518 0 362  LYS A H    1 c 
ATOM   5475 H HA   . LYS A 1 347 ? 4.991   24.499  -15.160 1.000 16.909 0 362  LYS A HA   1 c 
ATOM   5476 H HB2  . LYS A 1 347 ? 5.090   21.985  -13.839 1.000 20.664 0 362  LYS A HB2  1 c 
ATOM   5477 H HB3  . LYS A 1 347 ? 5.419   23.339  -13.071 1.000 20.868 0 362  LYS A HB3  1 c 
ATOM   5478 H HG2  . LYS A 1 347 ? 3.310   24.126  -13.334 1.000 27.115 0 362  LYS A HG2  1 c 
ATOM   5479 H HG3  . LYS A 1 347 ? 2.975   23.085  -14.465 1.000 26.889 0 362  LYS A HG3  1 c 
ATOM   5480 H HD2  . LYS A 1 347 ? 1.722   22.458  -12.673 1.000 35.933 0 362  LYS A HD2  1 c 
ATOM   5481 H HD3  . LYS A 1 347 ? 2.868   21.369  -12.777 1.000 35.995 0 362  LYS A HD3  1 c 
ATOM   5482 H HE2  . LYS A 1 347 ? 2.925   23.523  -10.977 1.000 44.461 0 362  LYS A HE2  1 c 
ATOM   5483 H HE3  . LYS A 1 347 ? 2.490   22.061  -10.581 1.000 44.462 0 362  LYS A HE3  1 c 
ATOM   5484 H HZ1  . LYS A 1 347 ? 4.982   22.982  -10.952 1.000 48.939 0 362  LYS A HZ1  1 c 
ATOM   5485 H HZ2  . LYS A 1 347 ? 4.766   21.607  -11.456 1.000 49.053 0 362  LYS A HZ2  1 c 
ATOM   5486 H HZ3  . LYS A 1 347 ? 4.529   21.922  -10.037 1.000 49.407 0 362  LYS A HZ3  1 c 
ATOM   5487 N N    . GLU A 1 348 ? 7.602   22.703  -15.602 1.000 16.531 0 363  GLU A N    1 ? 
ATOM   5488 C CA   . GLU A 1 348 ? 9.060   22.750  -15.718 1.000 15.845 0 363  GLU A CA   1 ? 
ATOM   5489 C C    . GLU A 1 348 ? 9.542   23.816  -16.721 1.000 17.173 0 363  GLU A C    1 ? 
ATOM   5490 O O    . GLU A 1 348 ? 10.380  24.665  -16.404 1.000 16.674 0 363  GLU A O    1 ? 
ATOM   5491 C CB   . GLU A 1 348 ? 9.688   21.435  -16.174 1.000 18.703 0 363  GLU A CB   1 ? 
ATOM   5492 C CG   . GLU A 1 348 ? 9.398   20.258  -15.262 1.000 21.488 0 363  GLU A CG   1 ? 
ATOM   5493 C CD   . GLU A 1 348 ? 9.880   20.335  -13.853 1.000 22.168 0 363  GLU A CD   1 ? 
ATOM   5494 O OE1  . GLU A 1 348 ? 10.331  21.373  -13.243 1.000 21.393 0 363  GLU A OE1  1 ? 
ATOM   5495 O OE2  . GLU A 1 348 ? 9.743   19.167  -13.336 1.000 23.330 0 363  GLU A OE2  1 ? 
ATOM   5496 H H    . GLU A 1 348 ? 7.168   21.936  -15.845 1.000 16.416 0 363  GLU A H    1 c 
ATOM   5497 H HA   . GLU A 1 348 ? 9.427   22.982  -14.829 1.000 16.758 0 363  GLU A HA   1 c 
ATOM   5498 H HB2  . GLU A 1 348 ? 9.359   21.225  -17.073 1.000 18.583 0 363  GLU A HB2  1 c 
ATOM   5499 H HB3  . GLU A 1 348 ? 10.659  21.554  -16.232 1.000 18.584 0 363  GLU A HB3  1 c 
ATOM   5500 H HG2  . GLU A 1 348 ? 8.429   20.118  -15.238 1.000 20.894 0 363  GLU A HG2  1 c 
ATOM   5501 H HG3  . GLU A 1 348 ? 9.786   19.454  -15.668 1.000 20.967 0 363  GLU A HG3  1 c 
ATOM   5502 N N    . PHE A 1 349 ? 8.952   23.842  -17.904 1.000 14.330 0 364  PHE A N    1 ? 
ATOM   5503 C CA   . PHE A 1 349 ? 9.301   24.826  -18.914 1.000 14.444 0 364  PHE A CA   1 ? 
ATOM   5504 C C    . PHE A 1 349 ? 8.969   26.235  -18.410 1.000 14.880 0 364  PHE A C    1 ? 
ATOM   5505 O O    . PHE A 1 349 ? 9.735   27.165  -18.669 1.000 14.872 0 364  PHE A O    1 ? 
ATOM   5506 C CB   . PHE A 1 349 ? 8.633   24.502  -20.251 1.000 14.905 0 364  PHE A CB   1 ? 
ATOM   5507 C CG   . PHE A 1 349 ? 9.353   23.430  -21.043 1.000 14.555 0 364  PHE A CG   1 ? 
ATOM   5508 C CD1  . PHE A 1 349 ? 10.576  23.693  -21.634 1.000 16.970 0 364  PHE A CD1  1 ? 
ATOM   5509 C CD2  . PHE A 1 349 ? 8.788   22.184  -21.253 1.000 16.629 0 364  PHE A CD2  1 ? 
ATOM   5510 C CE1  . PHE A 1 349 ? 11.259  22.729  -22.318 1.000 16.575 0 364  PHE A CE1  1 ? 
ATOM   5511 C CE2  . PHE A 1 349 ? 9.495   21.234  -21.956 1.000 16.316 0 364  PHE A CE2  1 ? 
ATOM   5512 C CZ   . PHE A 1 349 ? 10.695  21.509  -22.500 1.000 16.958 0 364  PHE A CZ   1 ? 
ATOM   5513 H H    . PHE A 1 349 ? 8.309   23.222  -18.096 1.000 15.002 0 364  PHE A H    1 c 
ATOM   5514 H HA   . PHE A 1 349 ? 10.285  24.779  -19.050 1.000 14.616 0 364  PHE A HA   1 c 
ATOM   5515 H HB2  . PHE A 1 349 ? 7.710   24.209  -20.080 1.000 14.739 0 364  PHE A HB2  1 c 
ATOM   5516 H HB3  . PHE A 1 349 ? 8.595   25.324  -20.790 1.000 14.724 0 364  PHE A HB3  1 c 
ATOM   5517 H HD1  . PHE A 1 349 ? 10.978  24.536  -21.499 1.000 16.284 0 364  PHE A HD1  1 c 
ATOM   5518 H HD2  . PHE A 1 349 ? 7.954   21.970  -20.867 1.000 16.053 0 364  PHE A HD2  1 c 
ATOM   5519 H HE1  . PHE A 1 349 ? 12.095  22.928  -22.706 1.000 16.755 0 364  PHE A HE1  1 c 
ATOM   5520 H HE2  . PHE A 1 349 ? 9.112   20.381  -22.088 1.000 16.525 0 364  PHE A HE2  1 c 
ATOM   5521 H HZ   . PHE A 1 349 ? 11.152  20.847  -22.995 1.000 16.701 0 364  PHE A HZ   1 c 
ATOM   5522 N N    . PHE A 1 350 ? 7.800   26.406  -17.810 1.000 13.980 0 365  PHE A N    1 ? 
ATOM   5523 C CA   . PHE A 1 350 ? 7.396   27.682  -17.234 1.000 15.049 0 365  PHE A CA   1 ? 
ATOM   5524 C C    . PHE A 1 350 ? 8.436   28.217  -16.242 1.000 15.380 0 365  PHE A C    1 ? 
ATOM   5525 O O    . PHE A 1 350 ? 8.857   29.381  -16.335 1.000 15.623 0 365  PHE A O    1 ? 
ATOM   5526 C CB   . PHE A 1 350 ? 5.991   27.567  -16.645 1.000 15.382 0 365  PHE A CB   1 ? 
ATOM   5527 C CG   . PHE A 1 350 ? 5.429   28.932  -16.272 1.000 16.933 0 365  PHE A CG   1 ? 
ATOM   5528 C CD1  . PHE A 1 350 ? 5.816   29.559  -15.095 1.000 18.030 0 365  PHE A CD1  1 ? 
ATOM   5529 C CD2  . PHE A 1 350 ? 4.606   29.615  -17.153 1.000 18.115 0 365  PHE A CD2  1 ? 
ATOM   5530 C CE1  . PHE A 1 350 ? 5.312   30.803  -14.778 1.000 18.463 0 365  PHE A CE1  1 ? 
ATOM   5531 C CE2  . PHE A 1 350 ? 4.091   30.857  -16.812 1.000 19.603 0 365  PHE A CE2  1 ? 
ATOM   5532 C CZ   . PHE A 1 350 ? 4.462   31.436  -15.652 1.000 19.382 0 365  PHE A CZ   1 ? 
ATOM   5533 H H    . PHE A 1 350 ? 7.220   25.701  -17.758 1.000 14.442 0 365  PHE A H    1 c 
ATOM   5534 H HA   . PHE A 1 350 ? 7.346   28.334  -17.983 1.000 14.968 0 365  PHE A HA   1 c 
ATOM   5535 H HB2  . PHE A 1 350 ? 5.401   27.142  -17.306 1.000 15.636 0 365  PHE A HB2  1 c 
ATOM   5536 H HB3  . PHE A 1 350 ? 6.027   27.001  -15.842 1.000 15.642 0 365  PHE A HB3  1 c 
ATOM   5537 H HD1  . PHE A 1 350 ? 6.391   29.115  -14.492 1.000 17.863 0 365  PHE A HD1  1 c 
ATOM   5538 H HD2  . PHE A 1 350 ? 4.339   29.201  -17.958 1.000 18.159 0 365  PHE A HD2  1 c 
ATOM   5539 H HE1  . PHE A 1 350 ? 5.555   31.219  -13.966 1.000 18.559 0 365  PHE A HE1  1 c 
ATOM   5540 H HE2  . PHE A 1 350 ? 3.514   31.310  -17.406 1.000 19.161 0 365  PHE A HE2  1 c 
ATOM   5541 H HZ   . PHE A 1 350 ? 4.124   32.289  -15.432 1.000 19.179 0 365  PHE A HZ   1 c 
ATOM   5542 N N    A GLU A 1 351 ? 8.846   27.386  -15.280 0.500 16.163 0 366  GLU A N    1 ? 
ATOM   5543 N N    B GLU A 1 351 ? 8.846   27.377  -15.290 0.500 16.459 0 366  GLU A N    1 ? 
ATOM   5544 C CA   A GLU A 1 351 ? 9.772   27.826  -14.253 0.500 15.855 0 366  GLU A CA   1 ? 
ATOM   5545 C CA   B GLU A 1 351 ? 9.772   27.797  -14.257 0.500 16.411 0 366  GLU A CA   1 ? 
ATOM   5546 C C    A GLU A 1 351 ? 11.135  28.142  -14.880 0.500 15.326 0 366  GLU A C    1 ? 
ATOM   5547 C C    B GLU A 1 351 ? 11.130  28.137  -14.879 0.500 15.609 0 366  GLU A C    1 ? 
ATOM   5548 O O    A GLU A 1 351 ? 11.786  29.097  -14.462 0.500 16.334 0 366  GLU A O    1 ? 
ATOM   5549 O O    B GLU A 1 351 ? 11.772  29.097  -14.458 0.500 16.590 0 366  GLU A O    1 ? 
ATOM   5550 C CB   A GLU A 1 351 ? 9.834   26.772  -13.143 0.500 17.548 0 366  GLU A CB   1 ? 
ATOM   5551 C CB   B GLU A 1 351 ? 9.839   26.684  -13.209 0.500 18.459 0 366  GLU A CB   1 ? 
ATOM   5552 C CG   A GLU A 1 351 ? 8.495   26.579  -12.432 0.500 18.567 0 366  GLU A CG   1 ? 
ATOM   5553 C CG   B GLU A 1 351 ? 10.675  27.058  -11.991 0.500 20.488 0 366  GLU A CG   1 ? 
ATOM   5554 C CD   A GLU A 1 351 ? 8.488   25.645  -11.220 0.500 24.548 0 366  GLU A CD   1 ? 
ATOM   5555 C CD   B GLU A 1 351 ? 10.591  26.147  -10.778 0.500 23.747 0 366  GLU A CD   1 ? 
ATOM   5556 O OE1  A GLU A 1 351 ? 7.436   25.558  -10.538 0.500 24.930 0 366  GLU A OE1  1 ? 
ATOM   5557 O OE1  B GLU A 1 351 ? 9.723   25.259  -10.714 0.500 27.918 0 366  GLU A OE1  1 ? 
ATOM   5558 O OE2  A GLU A 1 351 ? 9.525   25.013  -10.931 0.500 29.615 0 366  GLU A OE2  1 ? 
ATOM   5559 O OE2  B GLU A 1 351 ? 11.406  26.359  -9.875  0.500 26.248 0 366  GLU A OE2  1 ? 
ATOM   5560 H H    A GLU A 1 351 ? 8.540   26.525  -15.262 0.500 15.886 0 366  GLU A H    1 c 
ATOM   5561 H H    B GLU A 1 351 ? 8.537   26.517  -15.282 0.500 16.162 0 366  GLU A H    1 c 
ATOM   5562 H HA   A GLU A 1 351 ? 9.414   28.661  -13.857 0.500 16.108 0 366  GLU A HA   1 c 
ATOM   5563 H HA   B GLU A 1 351 ? 9.409   28.614  -13.828 0.500 16.612 0 366  GLU A HA   1 c 
ATOM   5564 H HB2  A GLU A 1 351 ? 10.117  25.919  -13.532 0.500 17.369 0 366  GLU A HB2  1 c 
ATOM   5565 H HB2  B GLU A 1 351 ? 8.929   26.468  -12.918 0.500 18.404 0 366  GLU A HB2  1 c 
ATOM   5566 H HB3  A GLU A 1 351 ? 10.510  27.042  -12.488 0.500 17.369 0 366  GLU A HB3  1 c 
ATOM   5567 H HB3  B GLU A 1 351 ? 10.219  25.882  -13.624 0.500 18.404 0 366  GLU A HB3  1 c 
ATOM   5568 H HG2  A GLU A 1 351 ? 8.172   27.457  -12.137 0.500 19.544 0 366  GLU A HG2  1 c 
ATOM   5569 H HG2  B GLU A 1 351 ? 11.616  27.106  -12.266 0.500 20.699 0 366  GLU A HG2  1 c 
ATOM   5570 H HG3  A GLU A 1 351 ? 7.842   26.243  -13.078 0.500 19.532 0 366  GLU A HG3  1 c 
ATOM   5571 H HG3  B GLU A 1 351 ? 10.419  27.961  -11.707 0.500 20.699 0 366  GLU A HG3  1 c 
ATOM   5572 N N    . VAL A 1 352 ? 11.588  27.343  -15.858 1.000 15.245 0 367  VAL A N    1 ? 
ATOM   5573 C CA   . VAL A 1 352 ? 12.875  27.630  -16.497 1.000 15.355 0 367  VAL A CA   1 ? 
ATOM   5574 C C    . VAL A 1 352 ? 12.838  28.965  -17.240 1.000 15.468 0 367  VAL A C    1 ? 
ATOM   5575 O O    . VAL A 1 352 ? 13.699  29.814  -17.035 1.000 15.394 0 367  VAL A O    1 ? 
ATOM   5576 C CB   . VAL A 1 352 ? 13.316  26.493  -17.419 1.000 16.232 0 367  VAL A CB   1 ? 
ATOM   5577 C CG1  . VAL A 1 352 ? 14.565  26.850  -18.244 1.000 16.099 0 367  VAL A CG1  1 ? 
ATOM   5578 C CG2  . VAL A 1 352 ? 13.596  25.226  -16.607 1.000 17.823 0 367  VAL A CG2  1 ? 
ATOM   5579 H H    . VAL A 1 352 ? 11.100  26.618  -16.126 1.000 15.393 0 367  VAL A H    1 c 
ATOM   5580 H HA   . VAL A 1 352 ? 13.542  27.705  -15.789 1.000 15.529 0 367  VAL A HA   1 c 
ATOM   5581 H HB   . VAL A 1 352 ? 12.572  26.308  -18.039 1.000 16.320 0 367  VAL A HB   1 c 
ATOM   5582 H HG11 . VAL A 1 352 ? 15.249  27.214  -17.657 1.000 16.136 0 367  VAL A HG11 1 c 
ATOM   5583 H HG12 . VAL A 1 352 ? 14.334  27.509  -18.919 1.000 16.133 0 367  VAL A HG12 1 c 
ATOM   5584 H HG13 . VAL A 1 352 ? 14.905  26.050  -18.679 1.000 16.135 0 367  VAL A HG13 1 c 
ATOM   5585 H HG21 . VAL A 1 352 ? 13.796  24.491  -17.211 1.000 17.333 0 367  VAL A HG21 1 c 
ATOM   5586 H HG22 . VAL A 1 352 ? 12.817  25.002  -16.072 1.000 17.310 0 367  VAL A HG22 1 c 
ATOM   5587 H HG23 . VAL A 1 352 ? 14.356  25.379  -16.021 1.000 17.333 0 367  VAL A HG23 1 c 
ATOM   5588 N N    . ALA A 1 353 ? 11.784  29.173  -18.035 1.000 15.376 0 368  ALA A N    1 ? 
ATOM   5589 C CA   . ALA A 1 353 ? 11.673  30.385  -18.844 1.000 15.366 0 368  ALA A CA   1 ? 
ATOM   5590 C C    . ALA A 1 353 ? 11.454  31.633  -17.996 1.000 16.547 0 368  ALA A C    1 ? 
ATOM   5591 O O    . ALA A 1 353 ? 11.981  32.695  -18.304 1.000 15.326 0 368  ALA A O    1 ? 
ATOM   5592 C CB   . ALA A 1 353 ? 10.551  30.274  -19.830 1.000 14.380 0 368  ALA A CB   1 ? 
ATOM   5593 H H    . ALA A 1 353 ? 11.120  28.547  -18.081 1.000 15.387 0 368  ALA A H    1 c 
ATOM   5594 H HA   . ALA A 1 353 ? 12.528  30.500  -19.343 1.000 15.388 0 368  ALA A HA   1 c 
ATOM   5595 H HB1  . ALA A 1 353 ? 10.673  29.481  -20.377 1.000 14.682 0 368  ALA A HB1  1 c 
ATOM   5596 H HB2  . ALA A 1 353 ? 9.704   30.210  -19.356 1.000 14.682 0 368  ALA A HB2  1 c 
ATOM   5597 H HB3  . ALA A 1 353 ? 10.539  31.060  -20.402 1.000 14.682 0 368  ALA A HB3  1 c 
ATOM   5598 N N    . ASN A 1 354 ? 10.637  31.502  -16.935 1.000 16.630 0 369  ASN A N    1 ? 
ATOM   5599 C CA   . ASN A 1 354 ? 10.047  32.668  -16.297 1.000 15.969 0 369  ASN A CA   1 ? 
ATOM   5600 C C    . ASN A 1 354 ? 10.617  32.907  -14.908 1.000 18.186 0 369  ASN A C    1 ? 
ATOM   5601 O O    . ASN A 1 354 ? 10.236  33.891  -14.267 1.000 20.020 0 369  ASN A O    1 ? 
ATOM   5602 C CB   . ASN A 1 354 ? 8.535   32.606  -16.318 1.000 16.289 0 369  ASN A CB   1 ? 
ATOM   5603 C CG   . ASN A 1 354 ? 8.056   32.466  -17.744 1.000 18.733 0 369  ASN A CG   1 ? 
ATOM   5604 O OD1  . ASN A 1 354 ? 8.465   33.259  -18.585 1.000 19.158 0 369  ASN A OD1  1 ? 
ATOM   5605 N ND2  . ASN A 1 354 ? 7.129   31.573  -18.022 1.000 18.373 0 369  ASN A ND2  1 ? 
ATOM   5606 H H    . ASN A 1 354 ? 10.435  30.671  -16.614 1.000 16.455 0 369  ASN A H    1 c 
ATOM   5607 H HA   . ASN A 1 354 ? 10.296  33.451  -16.836 1.000 16.567 0 369  ASN A HA   1 c 
ATOM   5608 H HB2  . ASN A 1 354 ? 8.228   31.842  -15.790 1.000 16.751 0 369  ASN A HB2  1 c 
ATOM   5609 H HB3  . ASN A 1 354 ? 8.166   33.422  -15.926 1.000 16.765 0 369  ASN A HB3  1 c 
ATOM   5610 H HD21 . ASN A 1 354 ? 7.136   30.788  -17.606 1.000 18.455 0 369  ASN A HD21 1 c 
ATOM   5611 H HD22 . ASN A 1 354 ? 6.504   31.756  -18.626 1.000 18.469 0 369  ASN A HD22 1 c 
ATOM   5612 N N    . ASP A 1 355 ? 11.524  32.038  -14.454 1.000 17.085 0 370  ASP A N    1 ? 
ATOM   5613 C CA   . ASP A 1 355 ? 12.158  32.238  -13.156 1.000 19.142 0 370  ASP A CA   1 ? 
ATOM   5614 C C    . ASP A 1 355 ? 13.667  31.953  -13.199 1.000 17.958 0 370  ASP A C    1 ? 
ATOM   5615 O O    . ASP A 1 355 ? 14.493  32.834  -12.898 1.000 18.247 0 370  ASP A O    1 ? 
ATOM   5616 C CB   . ASP A 1 355 ? 11.468  31.438  -12.077 1.000 20.680 0 370  ASP A CB   1 ? 
ATOM   5617 C CG   . ASP A 1 355 ? 11.961  31.864  -10.696 1.000 30.682 0 370  ASP A CG   1 ? 
ATOM   5618 O OD1  . ASP A 1 355 ? 11.658  33.013  -10.296 1.000 40.606 0 370  ASP A OD1  1 ? 
ATOM   5619 O OD2  . ASP A 1 355 ? 12.752  31.121  -10.125 1.000 44.027 0 370  ASP A OD2  1 ? 
ATOM   5620 H H    . ASP A 1 355 ? 11.752  31.309  -14.953 1.000 17.730 0 370  ASP A H    1 c 
ATOM   5621 H HA   . ASP A 1 355 ? 12.046  33.183  -12.909 1.000 18.974 0 370  ASP A HA   1 c 
ATOM   5622 H HB2  . ASP A 1 355 ? 10.500  31.580  -12.129 1.000 22.251 0 370  ASP A HB2  1 c 
ATOM   5623 H HB3  . ASP A 1 355 ? 11.653  30.484  -12.200 1.000 22.279 0 370  ASP A HB3  1 c 
ATOM   5624 N N    . VAL A 1 356 ? 14.034  30.767  -13.688 1.000 15.930 0 371  VAL A N    1 ? 
ATOM   5625 C CA   . VAL A 1 356 ? 15.412  30.318  -13.611 1.000 15.177 0 371  VAL A CA   1 ? 
ATOM   5626 C C    . VAL A 1 356 ? 16.296  31.086  -14.579 1.000 16.929 0 371  VAL A C    1 ? 
ATOM   5627 O O    . VAL A 1 356 ? 17.325  31.625  -14.161 1.000 16.304 0 371  VAL A O    1 ? 
ATOM   5628 C CB   . VAL A 1 356 ? 15.514  28.800  -13.797 1.000 15.985 0 371  VAL A CB   1 ? 
ATOM   5629 C CG1  . VAL A 1 356 ? 16.975  28.364  -13.681 1.000 17.804 0 371  VAL A CG1  1 ? 
ATOM   5630 C CG2  . VAL A 1 356 ? 14.693  28.050  -12.786 1.000 17.690 0 371  VAL A CG2  1 ? 
ATOM   5631 H H    . VAL A 1 356 ? 13.412  30.224  -14.078 1.000 16.263 0 371  VAL A H    1 c 
ATOM   5632 H HA   . VAL A 1 356 ? 15.729  30.519  -12.709 1.000 15.812 0 371  VAL A HA   1 c 
ATOM   5633 H HB   . VAL A 1 356 ? 15.189  28.585  -14.701 1.000 16.452 0 371  VAL A HB   1 c 
ATOM   5634 H HG11 . VAL A 1 356 ? 17.368  28.756  -12.882 1.000 17.249 0 371  VAL A HG11 1 c 
ATOM   5635 H HG12 . VAL A 1 356 ? 17.468  28.662  -14.464 1.000 17.248 0 371  VAL A HG12 1 c 
ATOM   5636 H HG13 . VAL A 1 356 ? 17.021  27.395  -13.621 1.000 17.251 0 371  VAL A HG13 1 c 
ATOM   5637 H HG21 . VAL A 1 356 ? 14.815  27.095  -12.914 1.000 17.195 0 371  VAL A HG21 1 c 
ATOM   5638 H HG22 . VAL A 1 356 ? 13.755  28.272  -12.897 1.000 17.150 0 371  VAL A HG22 1 c 
ATOM   5639 H HG23 . VAL A 1 356 ? 14.979  28.295  -11.890 1.000 17.166 0 371  VAL A HG23 1 c 
ATOM   5640 N N    . ILE A 1 357 ? 15.909  31.143  -15.855 1.000 15.818 0 372  ILE A N    1 ? 
ATOM   5641 C CA   . ILE A 1 357 ? 16.714  31.853  -16.836 1.000 15.384 0 372  ILE A CA   1 ? 
ATOM   5642 C C    . ILE A 1 357 ? 16.786  33.325  -16.430 1.000 16.546 0 372  ILE A C    1 ? 
ATOM   5643 O O    . ILE A 1 357 ? 17.862  33.907  -16.462 1.000 16.793 0 372  ILE A O    1 ? 
ATOM   5644 C CB   . ILE A 1 357 ? 16.240  31.606  -18.285 1.000 15.152 0 372  ILE A CB   1 ? 
ATOM   5645 C CG1  . ILE A 1 357 ? 16.624  30.192  -18.720 1.000 15.740 0 372  ILE A CG1  1 ? 
ATOM   5646 C CG2  . ILE A 1 357 ? 16.804  32.671  -19.208 1.000 16.566 0 372  ILE A CG2  1 ? 
ATOM   5647 C CD1  . ILE A 1 357 ? 16.121  29.745  -20.062 1.000 16.951 0 372  ILE A CD1  1 ? 
ATOM   5648 H H    . ILE A 1 357 ? 15.136  30.734  -16.121 1.000 15.963 0 372  ILE A H    1 c 
ATOM   5649 H HA   . ILE A 1 357 ? 17.621  31.495  -16.772 1.000 15.653 0 372  ILE A HA   1 c 
ATOM   5650 H HB   . ILE A 1 357 ? 15.266  31.671  -18.302 1.000 15.568 0 372  ILE A HB   1 c 
ATOM   5651 H HG12 . ILE A 1 357 ? 17.601  30.128  -18.724 1.000 15.874 0 372  ILE A HG12 1 c 
ATOM   5652 H HG13 . ILE A 1 357 ? 16.293  29.564  -18.045 1.000 15.875 0 372  ILE A HG13 1 c 
ATOM   5653 H HG21 . ILE A 1 357 ? 16.618  32.434  -20.132 1.000 16.143 0 372  ILE A HG21 1 c 
ATOM   5654 H HG22 . ILE A 1 357 ? 17.765  32.737  -19.081 1.000 16.139 0 372  ILE A HG22 1 c 
ATOM   5655 H HG23 . ILE A 1 357 ? 16.392  33.528  -19.010 1.000 16.139 0 372  ILE A HG23 1 c 
ATOM   5656 H HD11 . ILE A 1 357 ? 15.156  29.888  -20.114 1.000 16.580 0 372  ILE A HD11 1 c 
ATOM   5657 H HD12 . ILE A 1 357 ? 16.313  28.796  -20.181 1.000 16.580 0 372  ILE A HD12 1 c 
ATOM   5658 H HD13 . ILE A 1 357 ? 16.562  30.255  -20.768 1.000 16.578 0 372  ILE A HD13 1 c 
ATOM   5659 N N    . PRO A 1 358 ? 15.680  34.013  -16.086 1.000 16.081 0 373  PRO A N    1 ? 
ATOM   5660 C CA   . PRO A 1 358 ? 15.779  35.414  -15.667 1.000 16.589 0 373  PRO A CA   1 ? 
ATOM   5661 C C    . PRO A 1 358 ? 16.768  35.653  -14.517 1.000 18.036 0 373  PRO A C    1 ? 
ATOM   5662 O O    . PRO A 1 358 ? 17.538  36.616  -14.561 1.000 18.696 0 373  PRO A O    1 ? 
ATOM   5663 C CB   . PRO A 1 358 ? 14.318  35.766  -15.347 1.000 17.812 0 373  PRO A CB   1 ? 
ATOM   5664 C CG   . PRO A 1 358 ? 13.516  34.895  -16.314 1.000 16.454 0 373  PRO A CG   1 ? 
ATOM   5665 C CD   . PRO A 1 358 ? 14.286  33.578  -16.269 1.000 15.954 0 373  PRO A CD   1 ? 
ATOM   5666 H HA   . PRO A 1 358 ? 16.068  35.942  -16.452 1.000 16.975 0 373  PRO A HA   1 c 
ATOM   5667 H HB2  . PRO A 1 358 ? 14.099  35.548  -14.410 1.000 17.224 0 373  PRO A HB2  1 c 
ATOM   5668 H HB3  . PRO A 1 358 ? 14.142  36.723  -15.505 1.000 17.224 0 373  PRO A HB3  1 c 
ATOM   5669 H HG2  . PRO A 1 358 ? 12.593  34.777  -16.007 1.000 16.640 0 373  PRO A HG2  1 c 
ATOM   5670 H HG3  . PRO A 1 358 ? 13.513  35.274  -17.217 1.000 16.634 0 373  PRO A HG3  1 c 
ATOM   5671 H HD2  . PRO A 1 358 ? 13.987  33.020  -15.521 1.000 16.109 0 373  PRO A HD2  1 c 
ATOM   5672 H HD3  . PRO A 1 358 ? 14.177  33.081  -17.106 1.000 16.080 0 373  PRO A HD3  1 c 
ATOM   5673 N N    A ASN A 1 359 ? 16.749  34.779  -13.501 0.500 18.532 0 374  ASN A N    1 ? 
ATOM   5674 N N    B ASN A 1 359 ? 16.765  34.769  -13.523 0.500 18.093 0 374  ASN A N    1 ? 
ATOM   5675 C CA   A ASN A 1 359 ? 17.670  34.874  -12.363 0.500 20.348 0 374  ASN A CA   1 ? 
ATOM   5676 C CA   B ASN A 1 359 ? 17.654  34.922  -12.374 0.500 19.464 0 374  ASN A CA   1 ? 
ATOM   5677 C C    A ASN A 1 359 ? 19.118  34.767  -12.836 0.500 19.761 0 374  ASN A C    1 ? 
ATOM   5678 C C    B ASN A 1 359 ? 19.112  34.757  -12.819 0.500 19.373 0 374  ASN A C    1 ? 
ATOM   5679 O O    A ASN A 1 359 ? 20.001  35.540  -12.451 0.500 19.259 0 374  ASN A O    1 ? 
ATOM   5680 O O    B ASN A 1 359 ? 19.998  35.529  -12.439 0.500 19.175 0 374  ASN A O    1 ? 
ATOM   5681 C CB   A ASN A 1 359 ? 17.370  33.790  -11.332 0.500 22.244 0 374  ASN A CB   1 ? 
ATOM   5682 C CB   B ASN A 1 359 ? 17.136  34.025  -11.257 0.500 20.429 0 374  ASN A CB   1 ? 
ATOM   5683 C CG   A ASN A 1 359 ? 18.249  33.886  -10.098 0.500 27.205 0 374  ASN A CG   1 ? 
ATOM   5684 C CG   B ASN A 1 359 ? 15.882  34.595  -10.617 0.500 22.303 0 374  ASN A CG   1 ? 
ATOM   5685 O OD1  A ASN A 1 359 ? 17.836  34.433  -9.071  0.500 35.836 0 374  ASN A OD1  1 ? 
ATOM   5686 O OD1  B ASN A 1 359 ? 15.656  35.804  -10.685 0.500 30.264 0 374  ASN A OD1  1 ? 
ATOM   5687 N ND2  A ASN A 1 359 ? 19.477  33.408  -10.195 0.500 29.638 0 374  ASN A ND2  1 ? 
ATOM   5688 N ND2  B ASN A 1 359 ? 15.082  33.770  -9.951  0.500 28.810 0 374  ASN A ND2  1 ? 
ATOM   5689 H H    A ASN A 1 359 ? 16.138  34.100  -13.512 0.500 18.768 0 374  ASN A H    1 c 
ATOM   5690 H H    B ASN A 1 359 ? 16.196  34.055  -13.551 0.500 18.349 0 374  ASN A H    1 c 
ATOM   5691 H HA   A ASN A 1 359 ? 17.540  35.748  -11.929 0.500 20.208 0 374  ASN A HA   1 c 
ATOM   5692 H HA   B ASN A 1 359 ? 17.557  35.847  -12.053 0.500 19.338 0 374  ASN A HA   1 c 
ATOM   5693 H HB2  A ASN A 1 359 ? 16.433  33.861  -11.060 0.500 22.847 0 374  ASN A HB2  1 c 
ATOM   5694 H HB2  B ASN A 1 359 ? 16.938  33.139  -11.620 0.500 20.614 0 374  ASN A HB2  1 c 
ATOM   5695 H HB3  A ASN A 1 359 ? 17.496  32.913  -11.745 0.500 22.918 0 374  ASN A HB3  1 c 
ATOM   5696 H HB3  B ASN A 1 359 ? 17.830  33.927  -10.574 0.500 20.614 0 374  ASN A HB3  1 c 
ATOM   5697 H HD21 A ASN A 1 359 ? 19.752  33.045  -10.956 0.500 28.867 0 374  ASN A HD21 1 c 
ATOM   5698 H HD21 B ASN A 1 359 ? 15.280  32.907  -9.900  0.500 26.622 0 374  ASN A HD21 1 c 
ATOM   5699 H HD22 A ASN A 1 359 ? 20.024  33.451  -9.498  0.500 28.867 0 374  ASN A HD22 1 c 
ATOM   5700 H HD22 B ASN A 1 359 ? 14.350  34.083  -9.559  0.500 26.622 0 374  ASN A HD22 1 c 
ATOM   5701 N N    . LEU A 1 360 ? 19.371  33.763  -13.676 1.000 18.121 0 375  LEU A N    1 ? 
ATOM   5702 C CA   . LEU A 1 360 ? 20.703  33.508  -14.195 1.000 19.306 0 375  LEU A CA   1 ? 
ATOM   5703 C C    . LEU A 1 360 ? 21.230  34.702  -14.988 1.000 18.362 0 375  LEU A C    1 ? 
ATOM   5704 O O    . LEU A 1 360 ? 22.416  35.063  -14.852 1.000 19.532 0 375  LEU A O    1 ? 
ATOM   5705 C CB   . LEU A 1 360 ? 20.691  32.254  -15.072 1.000 22.775 0 375  LEU A CB   1 ? 
ATOM   5706 C CG   . LEU A 1 360 ? 20.908  30.901  -14.409 1.000 30.938 0 375  LEU A CG   1 ? 
ATOM   5707 C CD1  . LEU A 1 360 ? 20.953  29.885  -15.550 1.000 30.155 0 375  LEU A CD1  1 ? 
ATOM   5708 C CD2  . LEU A 1 360 ? 22.211  30.819  -13.630 1.000 31.428 0 375  LEU A CD2  1 ? 
ATOM   5709 H H    . LEU A 1 360 ? 18.689  33.214  -13.936 1.000 18.934 0 375  LEU A H    1 c 
ATOM   5710 H HA   . LEU A 1 360 ? 21.306  33.359  -13.425 1.000 19.583 0 375  LEU A HA   1 c 
ATOM   5711 H HB2  . LEU A 1 360 ? 19.830  32.225  -15.549 1.000 23.543 0 375  LEU A HB2  1 c 
ATOM   5712 H HB3  . LEU A 1 360 ? 21.382  32.366  -15.765 1.000 23.578 0 375  LEU A HB3  1 c 
ATOM   5713 H HG   . LEU A 1 360 ? 20.143  30.701  -13.811 1.000 29.168 0 375  LEU A HG   1 c 
ATOM   5714 H HD11 . LEU A 1 360 ? 20.116  29.914  -16.044 1.000 30.258 0 375  LEU A HD11 1 c 
ATOM   5715 H HD12 . LEU A 1 360 ? 21.082  28.994  -15.186 1.000 30.312 0 375  LEU A HD12 1 c 
ATOM   5716 H HD13 . LEU A 1 360 ? 21.688  30.099  -16.148 1.000 30.295 0 375  LEU A HD13 1 c 
ATOM   5717 H HD21 . LEU A 1 360 ? 22.155  31.384  -12.841 1.000 31.093 0 375  LEU A HD21 1 c 
ATOM   5718 H HD22 . LEU A 1 360 ? 22.945  31.120  -14.191 1.000 31.237 0 375  LEU A HD22 1 c 
ATOM   5719 H HD23 . LEU A 1 360 ? 22.369  29.899  -13.357 1.000 31.237 0 375  LEU A HD23 1 c 
ATOM   5720 N N    . LEU A 1 361 ? 20.376  35.273  -15.863 1.000 17.655 0 376  LEU A N    1 ? 
ATOM   5721 C CA   . LEU A 1 361 ? 20.799  36.354  -16.734 1.000 17.952 0 376  LEU A CA   1 ? 
ATOM   5722 C C    . LEU A 1 361 ? 20.939  37.658  -15.950 1.000 18.804 0 376  LEU A C    1 ? 
ATOM   5723 O O    . LEU A 1 361 ? 21.773  38.477  -16.340 1.000 18.622 0 376  LEU A O    1 ? 
ATOM   5724 C CB   . LEU A 1 361 ? 19.899  36.519  -17.959 1.000 17.677 0 376  LEU A CB   1 ? 
ATOM   5725 C CG   . LEU A 1 361 ? 19.737  35.305  -18.869 1.000 19.394 0 376  LEU A CG   1 ? 
ATOM   5726 C CD1  . LEU A 1 361 ? 18.776  35.701  -19.970 1.000 18.997 0 376  LEU A CD1  1 ? 
ATOM   5727 C CD2  . LEU A 1 361 ? 21.035  34.756  -19.412 1.000 21.560 0 376  LEU A CD2  1 ? 
ATOM   5728 H H    . LEU A 1 361 ? 19.514  34.974  -15.917 1.000 17.897 0 376  LEU A H    1 c 
ATOM   5729 H HA   . LEU A 1 361 ? 21.706  36.123  -17.058 1.000 18.042 0 376  LEU A HA   1 c 
ATOM   5730 H HB2  . LEU A 1 361 ? 19.006  36.791  -17.646 1.000 18.131 0 376  LEU A HB2  1 c 
ATOM   5731 H HB3  . LEU A 1 361 ? 20.254  37.263  -18.499 1.000 18.127 0 376  LEU A HB3  1 c 
ATOM   5732 H HG   . LEU A 1 361 ? 19.307  34.584  -18.342 1.000 19.358 0 376  LEU A HG   1 c 
ATOM   5733 H HD11 . LEU A 1 361 ? 17.918  35.942  -19.581 1.000 19.105 0 376  LEU A HD11 1 c 
ATOM   5734 H HD12 . LEU A 1 361 ? 18.655  34.954  -20.580 1.000 19.110 0 376  LEU A HD12 1 c 
ATOM   5735 H HD13 . LEU A 1 361 ? 19.135  36.461  -20.457 1.000 19.105 0 376  LEU A HD13 1 c 
ATOM   5736 H HD21 . LEU A 1 361 ? 21.575  34.415  -18.680 1.000 20.856 0 376  LEU A HD21 1 c 
ATOM   5737 H HD22 . LEU A 1 361 ? 21.520  35.463  -19.870 1.000 20.883 0 376  LEU A HD22 1 c 
ATOM   5738 H HD23 . LEU A 1 361 ? 20.847  34.036  -20.037 1.000 20.883 0 376  LEU A HD23 1 c 
ATOM   5739 N N    . LYS A 1 362 ? 20.110  37.864  -14.895 1.000 19.087 0 377  LYS A N    1 ? 
ATOM   5740 C CA   . LYS A 1 362 ? 20.271  39.037  -14.029 1.000 19.798 0 377  LYS A CA   1 ? 
ATOM   5741 C C    . LYS A 1 362 ? 21.639  39.013  -13.337 1.000 19.254 0 377  LYS A C    1 ? 
ATOM   5742 O O    . LYS A 1 362 ? 22.386  40.013  -13.356 1.000 19.672 0 377  LYS A O    1 ? 
ATOM   5743 C CB   . LYS A 1 362 ? 19.158  39.095  -12.994 1.000 21.490 0 377  LYS A CB   1 ? 
ATOM   5744 C CG   . LYS A 1 362 ? 19.298  40.274  -12.008 1.000 23.624 0 377  LYS A CG   1 ? 
ATOM   5745 C CD   . LYS A 1 362 ? 18.251  40.196  -10.909 1.000 32.490 0 377  LYS A CD   1 ? 
ATOM   5746 C CE   . LYS A 1 362 ? 18.324  41.369  -9.982  1.000 43.827 0 377  LYS A CE   1 ? 
ATOM   5747 N NZ   . LYS A 1 362 ? 17.444  41.108  -8.836  1.000 48.635 0 377  LYS A NZ   1 ? 
ATOM   5748 H H    . LYS A 1 362 ? 19.436  37.272  -14.720 1.000 19.170 0 377  LYS A H    1 c 
ATOM   5749 H HA   . LYS A 1 362 ? 20.219  39.849  -14.595 1.000 19.850 0 377  LYS A HA   1 c 
ATOM   5750 H HB2  . LYS A 1 362 ? 18.296  39.173  -13.455 1.000 21.546 0 377  LYS A HB2  1 c 
ATOM   5751 H HB3  . LYS A 1 362 ? 19.152  38.258  -12.483 1.000 21.546 0 377  LYS A HB3  1 c 
ATOM   5752 H HG2  . LYS A 1 362 ? 20.193  40.255  -11.606 1.000 24.852 0 377  LYS A HG2  1 c 
ATOM   5753 H HG3  . LYS A 1 362 ? 19.195  41.117  -12.500 1.000 24.877 0 377  LYS A HG3  1 c 
ATOM   5754 H HD2  . LYS A 1 362 ? 17.358  40.163  -11.316 1.000 32.406 0 377  LYS A HD2  1 c 
ATOM   5755 H HD3  . LYS A 1 362 ? 18.384  39.370  -10.395 1.000 32.470 0 377  LYS A HD3  1 c 
ATOM   5756 H HE2  . LYS A 1 362 ? 19.238  41.495  -9.669  1.000 41.936 0 377  LYS A HE2  1 c 
ATOM   5757 H HE3  . LYS A 1 362 ? 18.033  42.179  -10.439 1.000 41.936 0 377  LYS A HE3  1 c 
ATOM   5758 H HZ1  . LYS A 1 362 ? 17.746  40.390  -8.373  1.000 46.854 0 377  LYS A HZ1  1 c 
ATOM   5759 H HZ2  . LYS A 1 362 ? 16.602  40.943  -9.126  1.000 46.944 0 377  LYS A HZ2  1 c 
ATOM   5760 H HZ3  . LYS A 1 362 ? 17.434  41.830  -8.289  1.000 47.024 0 377  LYS A HZ3  1 c 
ATOM   5761 N N    . GLU A 1 363 ? 22.029  37.852  -12.805 1.000 18.346 0 378  GLU A N    1 ? 
ATOM   5762 C CA   . GLU A 1 363 ? 23.347  37.723  -12.190 1.000 18.419 0 378  GLU A CA   1 ? 
ATOM   5763 C C    . GLU A 1 363 ? 24.444  37.919  -13.238 1.000 20.312 0 378  GLU A C    1 ? 
ATOM   5764 O O    . GLU A 1 363 ? 25.410  38.658  -13.001 1.000 18.557 0 378  GLU A O    1 ? 
ATOM   5765 C CB   . GLU A 1 363 ? 23.512  36.390  -11.465 1.000 21.852 0 378  GLU A CB   1 ? 
ATOM   5766 C CG   . GLU A 1 363 ? 24.929  36.205  -10.920 1.000 25.567 0 378  GLU A CG   1 ? 
ATOM   5767 C CD   . GLU A 1 363 ? 25.144  34.910  -10.150 1.000 32.308 0 378  GLU A CD   1 ? 
ATOM   5768 O OE1  . GLU A 1 363 ? 24.517  33.916  -10.552 1.000 34.059 0 378  GLU A OE1  1 ? 
ATOM   5769 O OE2  . GLU A 1 363 ? 26.069  34.874  -9.284  1.000 30.030 0 378  GLU A OE2  1 ? 
ATOM   5770 H H    . GLU A 1 363 ? 21.469  37.130  -12.818 1.000 18.606 0 378  GLU A H    1 c 
ATOM   5771 H HA   . GLU A 1 363 ? 23.437  38.443  -11.515 1.000 19.339 0 378  GLU A HA   1 c 
ATOM   5772 H HB2  . GLU A 1 363 ? 22.870  36.348  -10.725 1.000 21.786 0 378  GLU A HB2  1 c 
ATOM   5773 H HB3  . GLU A 1 363 ? 23.302  35.662  -12.087 1.000 21.829 0 378  GLU A HB3  1 c 
ATOM   5774 H HG2  . GLU A 1 363 ? 25.565  36.226  -11.666 1.000 26.008 0 378  GLU A HG2  1 c 
ATOM   5775 H HG3  . GLU A 1 363 ? 25.144  36.956  -10.328 1.000 26.033 0 378  GLU A HG3  1 c 
ATOM   5776 N N    . ALA A 1 364 ? 24.297  37.304  -14.417 1.000 18.196 0 379  ALA A N    1 ? 
ATOM   5777 C CA   . ALA A 1 364 ? 25.293  37.491  -15.470 1.000 20.204 0 379  ALA A CA   1 ? 
ATOM   5778 C C    . ALA A 1 364 ? 25.445  38.959  -15.848 1.000 18.111 0 379  ALA A C    1 ? 
ATOM   5779 O O    . ALA A 1 364 ? 26.572  39.428  -16.122 1.000 20.703 0 379  ALA A O    1 ? 
ATOM   5780 C CB   . ALA A 1 364 ? 24.922  36.645  -16.682 1.000 21.453 0 379  ALA A CB   1 ? 
ATOM   5781 H H    . ALA A 1 364 ? 23.578  36.761  -14.569 1.000 19.128 0 379  ALA A H    1 c 
ATOM   5782 H HA   . ALA A 1 364 ? 26.171  37.175  -15.119 1.000 19.610 0 379  ALA A HA   1 c 
ATOM   5783 H HB1  . ALA A 1 364 ? 24.893  35.707  -16.430 1.000 21.078 0 379  ALA A HB1  1 c 
ATOM   5784 H HB2  . ALA A 1 364 ? 24.049  36.915  -17.015 1.000 21.078 0 379  ALA A HB2  1 c 
ATOM   5785 H HB3  . ALA A 1 364 ? 25.584  36.769  -17.383 1.000 21.078 0 379  ALA A HB3  1 c 
ATOM   5786 N N    . ALA A 1 365 ? 24.362  39.739  -15.831 1.000 18.113 0 380  ALA A N    1 ? 
ATOM   5787 C CA   . ALA A 1 365 ? 24.394  41.154  -16.147 1.000 19.522 0 380  ALA A CA   1 ? 
ATOM   5788 C C    . ALA A 1 365 ? 25.197  41.912  -15.089 1.000 20.139 0 380  ALA A C    1 ? 
ATOM   5789 O O    . ALA A 1 365 ? 25.968  42.778  -15.449 1.000 21.800 0 380  ALA A O    1 ? 
ATOM   5790 C CB   . ALA A 1 365 ? 23.032  41.788  -16.306 1.000 21.522 0 380  ALA A CB   1 ? 
ATOM   5791 H H    . ALA A 1 365 ? 23.557  39.364  -15.618 1.000 18.460 0 380  ALA A H    1 c 
ATOM   5792 H HA   . ALA A 1 365 ? 24.880  41.252  -17.012 1.000 19.726 0 380  ALA A HA   1 c 
ATOM   5793 H HB1  . ALA A 1 365 ? 22.546  41.344  -17.022 1.000 20.905 0 380  ALA A HB1  1 c 
ATOM   5794 H HB2  . ALA A 1 365 ? 22.532  41.701  -15.477 1.000 20.900 0 380  ALA A HB2  1 c 
ATOM   5795 H HB3  . ALA A 1 365 ? 23.133  42.730  -16.523 1.000 20.902 0 380  ALA A HB3  1 c 
ATOM   5796 N N    . SER A 1 366 ? 25.008  41.580  -13.821 1.000 19.945 0 381  SER A N    1 ? 
ATOM   5797 C CA   . SER A 1 366 ? 25.778  42.247  -12.770 1.000 19.904 0 381  SER A CA   1 ? 
ATOM   5798 C C    . SER A 1 366 ? 27.254  41.902  -12.901 1.000 19.862 0 381  SER A C    1 ? 
ATOM   5799 O O    . SER A 1 366 ? 28.113  42.750  -12.643 1.000 23.046 0 381  SER A O    1 ? 
ATOM   5800 C CB   . SER A 1 366 ? 25.270  41.845  -11.397 1.000 20.945 0 381  SER A CB   1 ? 
ATOM   5801 O OG   . SER A 1 366 ? 23.963  42.344  -11.178 1.000 25.774 0 381  SER A OG   1 ? 
ATOM   5802 H H    . SER A 1 366 ? 24.395  40.941  -13.594 1.000 19.972 0 381  SER A H    1 c 
ATOM   5803 H HA   . SER A 1 366 ? 25.671  43.227  -12.875 1.000 20.100 0 381  SER A HA   1 c 
ATOM   5804 H HB2  . SER A 1 366 ? 25.263  40.872  -11.326 1.000 21.758 0 381  SER A HB2  1 c 
ATOM   5805 H HB3  . SER A 1 366 ? 25.871  42.198  -10.715 1.000 21.749 0 381  SER A HB3  1 c 
ATOM   5806 H HG   . SER A 1 366 ? 23.707  42.101  -10.407 0.000 25.710 0 381  SER A HG   1 c 
ATOM   5807 N N    . LEU A 1 367 ? 27.565  40.635  -13.214 1.000 18.413 0 382  LEU A N    1 ? 
ATOM   5808 C CA   . LEU A 1 367 ? 28.950  40.197  -13.313 1.000 19.595 0 382  LEU A CA   1 ? 
ATOM   5809 C C    . LEU A 1 367 ? 29.596  40.854  -14.531 1.000 21.853 0 382  LEU A C    1 ? 
ATOM   5810 O O    . LEU A 1 367 ? 30.790  41.122  -14.499 1.000 23.096 0 382  LEU A O    1 ? 
ATOM   5811 C CB   . LEU A 1 367 ? 29.051  38.677  -13.377 1.000 18.516 0 382  LEU A CB   1 ? 
ATOM   5812 C CG   . LEU A 1 367 ? 28.635  37.921  -12.104 1.000 21.151 0 382  LEU A CG   1 ? 
ATOM   5813 C CD1  . LEU A 1 367 ? 28.566  36.429  -12.296 1.000 21.998 0 382  LEU A CD1  1 ? 
ATOM   5814 C CD2  . LEU A 1 367 ? 29.567  38.285  -10.955 1.000 20.953 0 382  LEU A CD2  1 ? 
ATOM   5815 H H    . LEU A 1 367 ? 26.899  40.028  -13.363 1.000 19.022 0 382  LEU A H    1 c 
ATOM   5816 H HA   . LEU A 1 367 ? 29.428  40.516  -12.507 1.000 19.584 0 382  LEU A HA   1 c 
ATOM   5817 H HB2  . LEU A 1 367 ? 28.489  38.363  -14.122 1.000 19.334 0 382  LEU A HB2  1 c 
ATOM   5818 H HB3  . LEU A 1 367 ? 29.984  38.440  -13.587 1.000 19.344 0 382  LEU A HB3  1 c 
ATOM   5819 H HG   . LEU A 1 367 ? 27.726  38.229  -11.855 1.000 20.746 0 382  LEU A HG   1 c 
ATOM   5820 H HD11 . LEU A 1 367 ? 27.919  36.220  -12.991 1.000 21.741 0 382  LEU A HD11 1 c 
ATOM   5821 H HD12 . LEU A 1 367 ? 28.294  36.006  -11.464 1.000 21.737 0 382  LEU A HD12 1 c 
ATOM   5822 H HD13 . LEU A 1 367 ? 29.440  36.094  -12.558 1.000 21.741 0 382  LEU A HD13 1 c 
ATOM   5823 H HD21 . LEU A 1 367 ? 29.391  39.197  -10.668 1.000 20.995 0 382  LEU A HD21 1 c 
ATOM   5824 H HD22 . LEU A 1 367 ? 30.490  38.212  -11.249 1.000 21.009 0 382  LEU A HD22 1 c 
ATOM   5825 H HD23 . LEU A 1 367 ? 29.417  37.678  -10.210 1.000 21.017 0 382  LEU A HD23 1 c 
ATOM   5826 N N    . LEU A 1 368 ? 28.820  41.050  -15.630 1.000 22.132 0 383  LEU A N    1 ? 
ATOM   5827 C CA   . LEU A 1 368 ? 29.349  41.748  -16.804 1.000 23.064 0 383  LEU A CA   1 ? 
ATOM   5828 C C    . LEU A 1 368 ? 29.724  43.184  -16.440 1.000 23.791 0 383  LEU A C    1 ? 
ATOM   5829 O O    . LEU A 1 368 ? 30.784  43.674  -16.899 1.000 24.897 0 383  LEU A O    1 ? 
ATOM   5830 C CB   . LEU A 1 368 ? 28.356  41.741  -17.971 1.000 22.000 0 383  LEU A CB   1 ? 
ATOM   5831 C CG   . LEU A 1 368 ? 28.876  42.367  -19.277 1.000 24.529 0 383  LEU A CG   1 ? 
ATOM   5832 C CD1  . LEU A 1 368 ? 30.106  41.673  -19.820 1.000 26.355 0 383  LEU A CD1  1 ? 
ATOM   5833 C CD2  . LEU A 1 368 ? 27.721  42.279  -20.278 1.000 27.759 0 383  LEU A CD2  1 ? 
ATOM   5834 H H    . LEU A 1 368 ? 27.961  40.739  -15.646 1.000 22.219 0 383  LEU A H    1 c 
ATOM   5835 H HA   . LEU A 1 368 ? 30.174  41.278  -17.084 1.000 22.914 0 383  LEU A HA   1 c 
ATOM   5836 H HB2  . LEU A 1 368 ? 28.100  40.807  -18.153 1.000 22.824 0 383  LEU A HB2  1 c 
ATOM   5837 H HB3  . LEU A 1 368 ? 27.547  42.229  -17.691 1.000 22.844 0 383  LEU A HB3  1 c 
ATOM   5838 H HG   . LEU A 1 368 ? 29.087  43.322  -19.114 1.000 24.926 0 383  LEU A HG   1 c 
ATOM   5839 H HD11 . LEU A 1 368 ? 30.794  41.645  -19.137 1.000 25.903 0 383  LEU A HD11 1 c 
ATOM   5840 H HD12 . LEU A 1 368 ? 30.439  42.160  -20.592 1.000 25.844 0 383  LEU A HD12 1 c 
ATOM   5841 H HD13 . LEU A 1 368 ? 29.877  40.766  -20.084 1.000 25.828 0 383  LEU A HD13 1 c 
ATOM   5842 H HD21 . LEU A 1 368 ? 26.958  42.776  -19.938 1.000 26.734 0 383  LEU A HD21 1 c 
ATOM   5843 H HD22 . LEU A 1 368 ? 27.470  41.349  -20.403 1.000 26.734 0 383  LEU A HD22 1 c 
ATOM   5844 H HD23 . LEU A 1 368 ? 27.999  42.656  -21.129 1.000 26.756 0 383  LEU A HD23 1 c 
ATOM   5845 N N    . GLU A 1 369 ? 28.867  43.858  -15.656 1.000 23.464 0 384  GLU A N    1 ? 
ATOM   5846 C CA   . GLU A 1 369 ? 29.134  45.205  -15.160 1.000 26.471 0 384  GLU A CA   1 ? 
ATOM   5847 C C    . GLU A 1 369 ? 30.474  45.209  -14.422 1.000 30.395 0 384  GLU A C    1 ? 
ATOM   5848 O O    . GLU A 1 369 ? 31.240  46.158  -14.567 1.000 35.290 0 384  GLU A O    1 ? 
ATOM   5849 C CB   . GLU A 1 369 ? 28.020  45.754  -14.265 1.000 33.503 0 384  GLU A CB   1 ? 
ATOM   5850 C CG   . GLU A 1 369 ? 28.099  47.250  -13.949 1.000 39.950 0 384  GLU A CG   1 ? 
ATOM   5851 C CD   . GLU A 1 369 ? 26.891  47.812  -13.184 1.000 52.254 0 384  GLU A CD   1 ? 
ATOM   5852 O OE1  . GLU A 1 369 ? 27.030  48.456  -12.100 1.000 52.153 0 384  GLU A OE1  1 ? 
ATOM   5853 O OE2  . GLU A 1 369 ? 25.759  47.582  -13.677 1.000 59.944 0 384  GLU A OE2  1 ? 
ATOM   5854 H H    . GLU A 1 369 ? 28.077  43.460  -15.425 1.000 24.220 0 384  GLU A H    1 c 
ATOM   5855 H HA   . GLU A 1 369 ? 29.214  45.806  -15.944 1.000 27.692 0 384  GLU A HA   1 c 
ATOM   5856 H HB2  . GLU A 1 369 ? 27.159  45.575  -14.697 1.000 33.143 0 384  GLU A HB2  1 c 
ATOM   5857 H HB3  . GLU A 1 369 ? 28.032  45.263  -13.417 1.000 32.995 0 384  GLU A HB3  1 c 
ATOM   5858 H HG2  . GLU A 1 369 ? 28.907  47.420  -13.419 1.000 40.760 0 384  GLU A HG2  1 c 
ATOM   5859 H HG3  . GLU A 1 369 ? 28.191  47.747  -14.790 1.000 40.802 0 384  GLU A HG3  1 c 
ATOM   5860 N N    . ALA A 1 370 ? 30.786  44.111  -13.721 1.000 25.461 0 385  ALA A N    1 ? 
ATOM   5861 C CA   . ALA A 1 370 ? 31.976  44.037  -12.898 1.000 28.684 0 385  ALA A CA   1 ? 
ATOM   5862 C C    . ALA A 1 370 ? 33.182  43.518  -13.686 1.000 30.923 0 385  ALA A C    1 ? 
ATOM   5863 O O    . ALA A 1 370 ? 34.221  43.213  -13.108 1.000 38.359 0 385  ALA A O    1 ? 
ATOM   5864 C CB   . ALA A 1 370 ? 31.668  43.185  -11.698 1.000 32.040 0 385  ALA A CB   1 ? 
ATOM   5865 H H    . ALA A 1 370 ? 30.223  43.392  -13.741 1.000 27.223 0 385  ALA A H    1 c 
ATOM   5866 H HA   . ALA A 1 370 ? 32.191  44.958  -12.585 1.000 29.040 0 385  ALA A HA   1 c 
ATOM   5867 H HB1  . ALA A 1 370 ? 30.917  43.564  -11.212 1.000 31.009 0 385  ALA A HB1  1 c 
ATOM   5868 H HB2  . ALA A 1 370 ? 31.443  42.284  -11.986 1.000 31.009 0 385  ALA A HB2  1 c 
ATOM   5869 H HB3  . ALA A 1 370 ? 32.444  43.150  -11.113 1.000 31.036 0 385  ALA A HB3  1 c 
ATOM   5870 N N    . GLY A 1 371 ? 33.042  43.355  -14.999 1.000 32.617 0 386  GLY A N    1 ? 
ATOM   5871 C CA   . GLY A 1 371 ? 34.190  43.111  -15.853 1.000 33.446 0 386  GLY A CA   1 ? 
ATOM   5872 C C    . GLY A 1 371 ? 34.419  41.651  -16.210 1.000 35.511 0 386  GLY A C    1 ? 
ATOM   5873 O O    . GLY A 1 371 ? 35.516  41.292  -16.647 1.000 36.227 0 386  GLY A O    1 ? 
ATOM   5874 H H    . GLY A 1 371 ? 32.211  43.382  -15.376 1.000 32.212 0 386  GLY A H    1 c 
ATOM   5875 H HA2  . GLY A 1 371 ? 34.075  43.629  -16.682 1.000 33.799 0 386  GLY A HA2  1 c 
ATOM   5876 H HA3  . GLY A 1 371 ? 34.996  43.458  -15.404 1.000 33.726 0 386  GLY A HA3  1 c 
ATOM   5877 N N    . SER A 1 372 ? 33.392  40.801  -16.128 1.000 28.043 0 399  SER A N    1 ? 
ATOM   5878 C CA   . SER A 1 372 ? 33.602  39.435  -16.526 1.000 28.806 0 399  SER A CA   1 ? 
ATOM   5879 C C    . SER A 1 372 ? 33.975  39.348  -18.004 1.000 32.313 0 399  SER A C    1 ? 
ATOM   5880 O O    . SER A 1 372 ? 33.528  40.167  -18.803 1.000 29.705 0 399  SER A O    1 ? 
ATOM   5881 C CB   . SER A 1 372 ? 32.424  38.549  -16.226 1.000 31.550 0 399  SER A CB   1 ? 
ATOM   5882 O OG   . SER A 1 372 ? 31.352  38.882  -17.094 1.000 38.863 0 399  SER A OG   1 ? 
ATOM   5883 H H    . SER A 1 372 ? 32.571  41.071  -15.832 1.000 29.898 0 399  SER A H    1 c 
ATOM   5884 H HA   . SER A 1 372 ? 34.372  39.093  -16.004 1.000 29.864 0 399  SER A HA   1 c 
ATOM   5885 H HB2  . SER A 1 372 ? 32.675  37.615  -16.355 1.000 32.484 0 399  SER A HB2  1 c 
ATOM   5886 H HB3  . SER A 1 372 ? 32.148  38.674  -15.298 1.000 32.484 0 399  SER A HB3  1 c 
ATOM   5887 H HG   . SER A 1 372 ? 30.691  38.383  -16.914 0.000 38.730 0 399  SER A HG   1 c 
ATOM   5888 N N    . GLN A 1 373 ? 34.769  38.317  -18.311 1.000 32.130 0 400  GLN A N    1 ? 
ATOM   5889 C CA   . GLN A 1 373 ? 35.136  37.960  -19.667 1.000 36.167 0 400  GLN A CA   1 ? 
ATOM   5890 C C    . GLN A 1 373 ? 34.562  36.583  -19.969 1.000 32.578 0 400  GLN A C    1 ? 
ATOM   5891 O O    . GLN A 1 373 ? 34.300  35.773  -19.068 1.000 36.426 0 400  GLN A O    1 ? 
ATOM   5892 C CB   . GLN A 1 373 ? 36.648  37.816  -19.857 1.000 45.456 0 400  GLN A CB   1 ? 
ATOM   5893 C CG   . GLN A 1 373 ? 37.483  39.015  -19.426 1.000 49.199 0 400  GLN A CG   1 ? 
ATOM   5894 C CD   . GLN A 1 373 ? 38.967  38.784  -19.647 1.000 62.189 0 400  GLN A CD   1 ? 
ATOM   5895 O OE1  . GLN A 1 373 ? 39.394  37.859  -20.354 1.000 71.462 0 400  GLN A OE1  1 ? 
ATOM   5896 N NE2  . GLN A 1 373 ? 39.785  39.630  -19.044 1.000 64.842 0 400  GLN A NE2  1 ? 
ATOM   5897 H H    . GLN A 1 373 ? 35.099  37.805  -17.630 1.000 32.992 0 400  GLN A H    1 c 
ATOM   5898 H HA   . GLN A 1 373 ? 34.764  38.626  -20.298 1.000 36.059 0 400  GLN A HA   1 c 
ATOM   5899 H HB2  . GLN A 1 373 ? 36.949  37.030  -19.354 1.000 43.861 0 400  GLN A HB2  1 c 
ATOM   5900 H HB3  . GLN A 1 373 ? 36.821  37.641  -20.806 1.000 43.959 0 400  GLN A HB3  1 c 
ATOM   5901 H HG2  . GLN A 1 373 ? 37.204  39.806  -19.933 1.000 50.972 0 400  GLN A HG2  1 c 
ATOM   5902 H HG3  . GLN A 1 373 ? 37.327  39.196  -18.475 1.000 50.874 0 400  GLN A HG3  1 c 
ATOM   5903 H HE21 . GLN A 1 373 ? 39.589  40.496  -19.029 1.000 63.898 0 400  GLN A HE21 1 c 
ATOM   5904 H HE22 . GLN A 1 373 ? 40.529  39.331  -18.660 1.000 63.986 0 400  GLN A HE22 1 c 
ATOM   5905 N N    . GLY A 1 374 ? 34.341  36.338  -21.255 1.000 36.959 0 401  GLY A N    1 ? 
ATOM   5906 C CA   . GLY A 1 374 ? 33.704  35.112  -21.696 1.000 38.679 0 401  GLY A CA   1 ? 
ATOM   5907 C C    . GLY A 1 374 ? 32.261  35.003  -21.195 1.000 35.270 0 401  GLY A C    1 ? 
ATOM   5908 O O    . GLY A 1 374 ? 31.730  33.902  -21.201 1.000 42.194 0 401  GLY A O    1 ? 
ATOM   5909 H H    . GLY A 1 374 ? 34.596  36.953  -21.882 1.000 36.232 0 401  GLY A H    1 c 
ATOM   5910 H HA2  . GLY A 1 374 ? 33.712  35.082  -22.681 1.000 37.469 0 401  GLY A HA2  1 c 
ATOM   5911 H HA3  . GLY A 1 374 ? 34.225  34.343  -21.365 1.000 37.477 0 401  GLY A HA3  1 c 
ATOM   5912 N N    . SER A 1 375 ? 31.629  36.137  -20.833 1.000 32.492 0 402  SER A N    1 ? 
ATOM   5913 C CA   . SER A 1 375 ? 30.241  36.160  -20.366 1.000 32.307 0 402  SER A CA   1 ? 
ATOM   5914 C C    . SER A 1 375 ? 29.317  35.519  -21.403 1.000 30.795 0 402  SER A C    1 ? 
ATOM   5915 O O    . SER A 1 375 ? 29.466  35.776  -22.591 1.000 26.859 0 402  SER A O    1 ? 
ATOM   5916 C CB   . SER A 1 375 ? 29.774  37.565  -20.055 1.000 28.562 0 402  SER A CB   1 ? 
ATOM   5917 O OG   . SER A 1 375 ? 28.383  37.606  -19.709 1.000 29.476 0 402  SER A OG   1 ? 
ATOM   5918 H H    . SER A 1 375 ? 32.076  36.931  -20.897 1.000 33.117 0 402  SER A H    1 c 
ATOM   5919 H HA   . SER A 1 375 ? 30.190  35.624  -19.534 1.000 31.302 0 402  SER A HA   1 c 
ATOM   5920 H HB2  . SER A 1 375 ? 30.301  37.921  -19.315 1.000 29.638 0 402  SER A HB2  1 c 
ATOM   5921 H HB3  . SER A 1 375 ? 29.927  38.133  -20.834 1.000 29.619 0 402  SER A HB3  1 c 
ATOM   5922 H HG   . SER A 1 375 ? 28.169  38.401  -19.543 0.000 29.490 0 402  SER A HG   1 c 
ATOM   5923 N N    . ALA A 1 376 ? 28.326  34.717  -20.963 1.000 24.764 0 403  ALA A N    1 ? 
ATOM   5924 C CA   . ALA A 1 376 ? 27.289  34.264  -21.874 1.000 26.092 0 403  ALA A CA   1 ? 
ATOM   5925 C C    . ALA A 1 376 ? 26.625  35.467  -22.562 1.000 22.109 0 403  ALA A C    1 ? 
ATOM   5926 O O    . ALA A 1 376 ? 26.197  35.307  -23.692 1.000 22.023 0 403  ALA A O    1 ? 
ATOM   5927 C CB   . ALA A 1 376 ? 26.240  33.401  -21.154 1.000 25.969 0 403  ALA A CB   1 ? 
ATOM   5928 H H    . ALA A 1 376 ? 28.301  34.454  -20.088 1.000 26.465 0 403  ALA A H    1 c 
ATOM   5929 H HA   . ALA A 1 376 ? 27.725  33.712  -22.581 1.000 25.042 0 403  ALA A HA   1 c 
ATOM   5930 H HB1  . ALA A 1 376 ? 26.645  32.566  -20.865 1.000 26.009 0 403  ALA A HB1  1 c 
ATOM   5931 H HB2  . ALA A 1 376 ? 25.901  33.878  -20.377 1.000 26.009 0 403  ALA A HB2  1 c 
ATOM   5932 H HB3  . ALA A 1 376 ? 25.503  33.208  -21.758 1.000 26.022 0 403  ALA A HB3  1 c 
ATOM   5933 N N    . LEU A 1 377 ? 26.513  36.627  -21.902 1.000 20.290 0 404  LEU A N    1 ? 
ATOM   5934 C CA   . LEU A 1 377 ? 25.768  37.770  -22.442 1.000 20.758 0 404  LEU A CA   1 ? 
ATOM   5935 C C    . LEU A 1 377 ? 26.541  38.364  -23.623 1.000 20.560 0 404  LEU A C    1 ? 
ATOM   5936 O O    . LEU A 1 377 ? 25.952  39.148  -24.367 1.000 20.549 0 404  LEU A O    1 ? 
ATOM   5937 C CB   . LEU A 1 377 ? 25.380  38.858  -21.453 1.000 21.711 0 404  LEU A CB   1 ? 
ATOM   5938 C CG   . LEU A 1 377 ? 24.527  38.387  -20.263 1.000 22.695 0 404  LEU A CG   1 ? 
ATOM   5939 C CD1  . LEU A 1 377 ? 24.168  39.530  -19.323 1.000 22.257 0 404  LEU A CD1  1 ? 
ATOM   5940 C CD2  . LEU A 1 377 ? 23.278  37.711  -20.804 1.000 24.028 0 404  LEU A CD2  1 ? 
ATOM   5941 H H    . LEU A 1 377 ? 26.900  36.711  -21.079 1.000 20.892 0 404  LEU A H    1 c 
ATOM   5942 H HA   . LEU A 1 377 ? 24.931  37.403  -22.822 1.000 20.853 0 404  LEU A HA   1 c 
ATOM   5943 H HB2  . LEU A 1 377 ? 26.205  39.266  -21.104 1.000 21.702 0 404  LEU A HB2  1 c 
ATOM   5944 H HB3  . LEU A 1 377 ? 24.880  39.553  -21.940 1.000 21.692 0 404  LEU A HB3  1 c 
ATOM   5945 H HG   . LEU A 1 377 ? 25.048  37.715  -19.752 1.000 22.670 0 404  LEU A HG   1 c 
ATOM   5946 H HD11 . LEU A 1 377 ? 24.981  39.933  -18.977 1.000 22.372 0 404  LEU A HD11 1 c 
ATOM   5947 H HD12 . LEU A 1 377 ? 23.637  39.188  -18.583 1.000 22.393 0 404  LEU A HD12 1 c 
ATOM   5948 H HD13 . LEU A 1 377 ? 23.655  40.199  -19.805 1.000 22.400 0 404  LEU A HD13 1 c 
ATOM   5949 H HD21 . LEU A 1 377 ? 23.502  36.822  -21.127 1.000 23.582 0 404  LEU A HD21 1 c 
ATOM   5950 H HD22 . LEU A 1 377 ? 22.913  38.239  -21.535 1.000 23.602 0 404  LEU A HD22 1 c 
ATOM   5951 H HD23 . LEU A 1 377 ? 22.616  37.639  -20.096 1.000 23.598 0 404  LEU A HD23 1 c 
ATOM   5952 N N    . GLN A 1 378 ? 27.843  38.029  -23.751 1.000 22.074 0 405  GLN A N    1 ? 
ATOM   5953 C CA   . GLN A 1 378 ? 28.608  38.506  -24.901 1.000 21.610 0 405  GLN A CA   1 ? 
ATOM   5954 C C    . GLN A 1 378 ? 28.854  37.407  -25.914 1.000 24.984 0 405  GLN A C    1 ? 
ATOM   5955 O O    . GLN A 1 378 ? 29.637  37.580  -26.858 1.000 23.806 0 405  GLN A O    1 ? 
ATOM   5956 C CB   . GLN A 1 378 ? 29.871  39.192  -24.401 1.000 23.899 0 405  GLN A CB   1 ? 
ATOM   5957 C CG   . GLN A 1 378 ? 29.530  40.446  -23.617 1.000 24.920 0 405  GLN A CG   1 ? 
ATOM   5958 C CD   . GLN A 1 378 ? 30.755  41.261  -23.304 1.000 30.615 0 405  GLN A CD   1 ? 
ATOM   5959 O OE1  . GLN A 1 378 ? 31.806  40.701  -22.968 1.000 33.713 0 405  GLN A OE1  1 ? 
ATOM   5960 N NE2  . GLN A 1 378 ? 30.613  42.564  -23.498 1.000 32.334 0 405  GLN A NE2  1 ? 
ATOM   5961 H H    . GLN A 1 378 ? 28.262  37.525  -23.114 1.000 21.627 0 405  GLN A H    1 c 
ATOM   5962 H HA   . GLN A 1 378 ? 28.071  39.203  -25.352 1.000 22.706 0 405  GLN A HA   1 c 
ATOM   5963 H HB2  . GLN A 1 378 ? 30.371  38.574  -23.828 1.000 23.632 0 405  GLN A HB2  1 c 
ATOM   5964 H HB3  . GLN A 1 378 ? 30.438  39.429  -25.165 1.000 23.625 0 405  GLN A HB3  1 c 
ATOM   5965 H HG2  . GLN A 1 378 ? 28.902  40.993  -24.135 1.000 25.960 0 405  GLN A HG2  1 c 
ATOM   5966 H HG3  . GLN A 1 378 ? 29.090  40.196  -22.777 1.000 25.882 0 405  GLN A HG3  1 c 
ATOM   5967 H HE21 . GLN A 1 378 ? 29.848  42.964  -23.286 1.000 31.687 0 405  GLN A HE21 1 c 
ATOM   5968 H HE22 . GLN A 1 378 ? 31.284  43.036  -23.840 1.000 31.769 0 405  GLN A HE22 1 c 
ATOM   5969 N N    . ASP A 1 379 ? 28.173  36.257  -25.746 1.000 20.897 0 406  ASP A N    1 ? 
ATOM   5970 C CA   . ASP A 1 379 ? 28.420  35.135  -26.619 1.000 22.049 0 406  ASP A CA   1 ? 
ATOM   5971 C C    . ASP A 1 379 ? 27.191  34.945  -27.496 1.000 21.457 0 406  ASP A C    1 ? 
ATOM   5972 O O    . ASP A 1 379 ? 26.125  34.583  -27.014 1.000 20.027 0 406  ASP A O    1 ? 
ATOM   5973 C CB   . ASP A 1 379 ? 28.724  33.829  -25.887 1.000 21.604 0 406  ASP A CB   1 ? 
ATOM   5974 C CG   . ASP A 1 379 ? 29.047  32.629  -26.769 1.000 23.731 0 406  ASP A CG   1 ? 
ATOM   5975 O OD1  . ASP A 1 379 ? 28.945  32.707  -28.016 1.000 25.635 0 406  ASP A OD1  1 ? 
ATOM   5976 O OD2  . ASP A 1 379 ? 29.297  31.559  -26.178 1.000 34.832 0 406  ASP A OD2  1 ? 
ATOM   5977 H H    . ASP A 1 379 ? 27.544  36.180  -25.088 1.000 22.061 0 406  ASP A H    1 c 
ATOM   5978 H HA   . ASP A 1 379 ? 29.193  35.339  -27.187 1.000 21.652 0 406  ASP A HA   1 c 
ATOM   5979 H HB2  . ASP A 1 379 ? 29.488  33.979  -25.292 1.000 22.176 0 406  ASP A HB2  1 c 
ATOM   5980 H HB3  . ASP A 1 379 ? 27.953  33.596  -25.329 1.000 22.166 0 406  ASP A HB3  1 c 
ATOM   5981 N N    . PRO A 1 380 ? 27.259  35.194  -28.813 1.000 18.953 0 407  PRO A N    1 ? 
ATOM   5982 C CA   . PRO A 1 380 ? 26.110  34.947  -29.676 1.000 19.159 0 407  PRO A CA   1 ? 
ATOM   5983 C C    . PRO A 1 380 ? 25.582  33.512  -29.696 1.000 19.754 0 407  PRO A C    1 ? 
ATOM   5984 O O    . PRO A 1 380 ? 24.406  33.299  -29.947 1.000 20.772 0 407  PRO A O    1 ? 
ATOM   5985 C CB   . PRO A 1 380 ? 26.594  35.355  -31.078 1.000 21.380 0 407  PRO A CB   1 ? 
ATOM   5986 C CG   . PRO A 1 380 ? 27.833  36.118  -30.825 1.000 23.742 0 407  PRO A CG   1 ? 
ATOM   5987 C CD   . PRO A 1 380 ? 28.428  35.721  -29.528 1.000 22.385 0 407  PRO A CD   1 ? 
ATOM   5988 H HA   . PRO A 1 380 ? 25.381  35.557  -29.398 1.000 19.613 0 407  PRO A HA   1 c 
ATOM   5989 H HB2  . PRO A 1 380 ? 26.783  34.568  -31.624 1.000 21.793 0 407  PRO A HB2  1 c 
ATOM   5990 H HB3  . PRO A 1 380 ? 25.922  35.913  -31.536 1.000 21.457 0 407  PRO A HB3  1 c 
ATOM   5991 H HG2  . PRO A 1 380 ? 28.476  35.954  -31.546 1.000 22.859 0 407  PRO A HG2  1 c 
ATOM   5992 H HG3  . PRO A 1 380 ? 27.634  37.078  -30.816 1.000 22.859 0 407  PRO A HG3  1 c 
ATOM   5993 H HD2  . PRO A 1 380 ? 29.117  35.030  -29.648 1.000 21.834 0 407  PRO A HD2  1 c 
ATOM   5994 H HD3  . PRO A 1 380 ? 28.815  36.496  -29.065 1.000 21.843 0 407  PRO A HD3  1 c 
ATOM   5995 N N    . GLU A 1 381 ? 26.449  32.527  -29.417 1.000 22.192 0 408  GLU A N    1 ? 
ATOM   5996 C CA   . GLU A 1 381 ? 26.006  31.142  -29.324 1.000 23.670 0 408  GLU A CA   1 ? 
ATOM   5997 C C    . GLU A 1 381 ? 25.013  30.979  -28.153 1.000 20.278 0 408  GLU A C    1 ? 
ATOM   5998 O O    . GLU A 1 381 ? 24.036  30.230  -28.265 1.000 22.725 0 408  GLU A O    1 ? 
ATOM   5999 C CB   . GLU A 1 381 ? 27.238  30.247  -29.150 1.000 29.755 0 408  GLU A CB   1 ? 
ATOM   6000 C CG   . GLU A 1 381 ? 27.118  28.883  -29.819 1.000 45.622 0 408  GLU A CG   1 ? 
ATOM   6001 C CD   . GLU A 1 381 ? 27.198  28.995  -31.332 1.000 54.117 0 408  GLU A CD   1 ? 
ATOM   6002 O OE1  . GLU A 1 381 ? 28.292  29.330  -31.835 1.000 67.525 0 408  GLU A OE1  1 ? 
ATOM   6003 O OE2  . GLU A 1 381 ? 26.164  28.787  -32.010 1.000 56.339 0 408  GLU A OE2  1 ? 
ATOM   6004 H H    . GLU A 1 381 ? 27.332  32.722  -29.287 1.000 21.975 0 408  GLU A H    1 c 
ATOM   6005 H HA   . GLU A 1 381 ? 25.545  30.904  -30.168 1.000 23.870 0 408  GLU A HA   1 c 
ATOM   6006 H HB2  . GLU A 1 381 ? 28.019  30.704  -29.526 1.000 31.231 0 408  GLU A HB2  1 c 
ATOM   6007 H HB3  . GLU A 1 381 ? 27.402  30.117  -28.193 1.000 31.120 0 408  GLU A HB3  1 c 
ATOM   6008 H HG2  . GLU A 1 381 ? 27.841  28.299  -29.503 1.000 43.017 0 408  GLU A HG2  1 c 
ATOM   6009 H HG3  . GLU A 1 381 ? 26.261  28.473  -29.574 1.000 43.074 0 408  GLU A HG3  1 c 
ATOM   6010 N N    . CYS A 1 382 ? 25.236  31.706  -27.061 1.000 18.380 0 409  CYS A N    1 ? 
ATOM   6011 C CA   . CYS A 1 382 ? 24.325  31.725  -25.923 1.000 20.537 0 409  CYS A CA   1 ? 
ATOM   6012 C C    . CYS A 1 382 ? 22.970  32.340  -26.283 1.000 18.740 0 409  CYS A C    1 ? 
ATOM   6013 O O    . CYS A 1 382 ? 21.928  31.832  -25.895 1.000 16.811 0 409  CYS A O    1 ? 
ATOM   6014 C CB   . CYS A 1 382 ? 24.886  32.430  -24.722 1.000 22.879 0 409  CYS A CB   1 ? 
ATOM   6015 S SG   . CYS A 1 382 ? 26.233  31.468  -23.965 1.000 30.032 0 409  CYS A SG   1 ? 
ATOM   6016 H H    . CYS A 1 382 ? 25.996  32.211  -27.015 1.000 19.360 0 409  CYS A H    1 c 
ATOM   6017 H HA   . CYS A 1 382 ? 24.169  30.784  -25.656 1.000 20.189 0 409  CYS A HA   1 c 
ATOM   6018 H HB2  . CYS A 1 382 ? 25.231  33.310  -24.988 1.000 23.424 0 409  CYS A HB2  1 c 
ATOM   6019 H HB3  . CYS A 1 382 ? 24.175  32.563  -24.056 1.000 23.424 0 409  CYS A HB3  1 c 
ATOM   6020 H HG   . CYS A 1 382 ? 26.491  32.233  -23.065 0.000 30.050 0 409  CYS A HG   1 c 
ATOM   6021 N N    . PHE A 1 383 ? 22.973  33.452  -27.024 1.000 17.360 0 410  PHE A N    1 ? 
ATOM   6022 C CA   . PHE A 1 383 ? 21.746  34.031  -27.511 1.000 15.479 0 410  PHE A CA   1 ? 
ATOM   6023 C C    . PHE A 1 383 ? 21.053  33.032  -28.429 1.000 14.699 0 410  PHE A C    1 ? 
ATOM   6024 O O    . PHE A 1 383 ? 19.832  32.878  -28.322 1.000 15.687 0 410  PHE A O    1 ? 
ATOM   6025 C CB   . PHE A 1 383 ? 22.045  35.371  -28.230 1.000 16.548 0 410  PHE A CB   1 ? 
ATOM   6026 C CG   . PHE A 1 383 ? 20.793  36.125  -28.623 1.000 16.757 0 410  PHE A CG   1 ? 
ATOM   6027 C CD1  . PHE A 1 383 ? 19.910  36.626  -27.675 1.000 17.548 0 410  PHE A CD1  1 ? 
ATOM   6028 C CD2  . PHE A 1 383 ? 20.519  36.380  -29.957 1.000 16.743 0 410  PHE A CD2  1 ? 
ATOM   6029 C CE1  . PHE A 1 383 ? 18.789  37.310  -28.090 1.000 17.156 0 410  PHE A CE1  1 ? 
ATOM   6030 C CE2  . PHE A 1 383 ? 19.404  37.099  -30.345 1.000 15.115 0 410  PHE A CE2  1 ? 
ATOM   6031 C CZ   . PHE A 1 383 ? 18.519  37.523  -29.412 1.000 17.479 0 410  PHE A CZ   1 ? 
ATOM   6032 H H    . PHE A 1 383 ? 23.766  33.860  -27.224 1.000 17.246 0 410  PHE A H    1 c 
ATOM   6033 H HA   . PHE A 1 383 ? 21.153  34.214  -26.735 1.000 15.895 0 410  PHE A HA   1 c 
ATOM   6034 H HB2  . PHE A 1 383 ? 22.584  35.935  -27.633 1.000 16.350 0 410  PHE A HB2  1 c 
ATOM   6035 H HB3  . PHE A 1 383 ? 22.575  35.184  -29.037 1.000 16.353 0 410  PHE A HB3  1 c 
ATOM   6036 H HD1  . PHE A 1 383 ? 20.059  36.466  -26.757 1.000 17.253 0 410  PHE A HD1  1 c 
ATOM   6037 H HD2  . PHE A 1 383 ? 21.117  36.069  -30.616 1.000 16.468 0 410  PHE A HD2  1 c 
ATOM   6038 H HE1  . PHE A 1 383 ? 18.182  37.629  -27.441 1.000 17.297 0 410  PHE A HE1  1 c 
ATOM   6039 H HE2  . PHE A 1 383 ? 19.227  37.235  -31.262 1.000 16.045 0 410  PHE A HE2  1 c 
ATOM   6040 H HZ   . PHE A 1 383 ? 17.757  38.017  -29.669 1.000 16.816 0 410  PHE A HZ   1 c 
ATOM   6041 N N    . ALA A 1 384 ? 21.786  32.337  -29.321 1.000 15.277 0 411  ALA A N    1 ? 
ATOM   6042 C CA   . ALA A 1 384 ? 21.163  31.322  -30.171 1.000 16.223 0 411  ALA A CA   1 ? 
ATOM   6043 C C    . ALA A 1 384 ? 20.483  30.233  -29.339 1.000 15.470 0 411  ALA A C    1 ? 
ATOM   6044 O O    . ALA A 1 384 ? 19.397  29.791  -29.705 1.000 15.869 0 411  ALA A O    1 ? 
ATOM   6045 C CB   . ALA A 1 384 ? 22.160  30.732  -31.146 1.000 16.971 0 411  ALA A CB   1 ? 
ATOM   6046 H H    . ALA A 1 384 ? 22.681  32.500  -29.404 1.000 15.365 0 411  ALA A H    1 c 
ATOM   6047 H HA   . ALA A 1 384 ? 20.451  31.778  -30.698 1.000 16.026 0 411  ALA A HA   1 c 
ATOM   6048 H HB1  . ALA A 1 384 ? 22.524  31.437  -31.708 1.000 16.753 0 411  ALA A HB1  1 c 
ATOM   6049 H HB2  . ALA A 1 384 ? 22.884  30.306  -30.658 1.000 16.775 0 411  ALA A HB2  1 c 
ATOM   6050 H HB3  . ALA A 1 384 ? 21.718  30.072  -31.706 1.000 16.753 0 411  ALA A HB3  1 c 
ATOM   6051 N N    . HIS A 1 385 ? 21.099  29.816  -28.224 1.000 15.170 0 412  HIS A N    1 ? 
ATOM   6052 C CA   . HIS A 1 385 ? 20.500  28.757  -27.410 1.000 15.572 0 412  HIS A CA   1 ? 
ATOM   6053 C C    . HIS A 1 385 ? 19.170  29.241  -26.844 1.000 14.351 0 412  HIS A C    1 ? 
ATOM   6054 O O    . HIS A 1 385 ? 18.174  28.503  -26.795 1.000 16.135 0 412  HIS A O    1 ? 
ATOM   6055 C CB   . HIS A 1 385 ? 21.462  28.297  -26.301 1.000 16.174 0 412  HIS A CB   1 ? 
ATOM   6056 C CG   . HIS A 1 385 ? 22.683  27.587  -26.780 1.000 16.373 0 412  HIS A CG   1 ? 
ATOM   6057 N ND1  . HIS A 1 385 ? 22.692  26.789  -27.892 1.000 21.303 0 412  HIS A ND1  1 ? 
ATOM   6058 C CD2  . HIS A 1 385 ? 23.931  27.582  -26.282 1.000 19.009 0 412  HIS A CD2  1 ? 
ATOM   6059 C CE1  . HIS A 1 385 ? 23.953  26.337  -28.055 1.000 21.530 0 412  HIS A CE1  1 ? 
ATOM   6060 N NE2  . HIS A 1 385 ? 24.697  26.797  -27.109 1.000 20.308 0 412  HIS A NE2  1 ? 
ATOM   6061 H H    . HIS A 1 385 ? 21.896  30.183  -27.968 1.000 15.356 0 412  HIS A H    1 c 
ATOM   6062 H HA   . HIS A 1 385 ? 20.318  27.988  -28.004 1.000 15.395 0 412  HIS A HA   1 c 
ATOM   6063 H HB2  . HIS A 1 385 ? 21.738  29.084  -25.783 1.000 16.081 0 412  HIS A HB2  1 c 
ATOM   6064 H HB3  . HIS A 1 385 ? 20.972  27.705  -25.690 1.000 16.073 0 412  HIS A HB3  1 c 
ATOM   6065 H HD1  . HIS A 1 385 ? 22.000  26.628  -28.412 0.000 21.370 0 412  HIS A HD1  1 c 
ATOM   6066 H HD2  . HIS A 1 385 ? 24.235  28.043  -25.526 1.000 18.658 0 412  HIS A HD2  1 c 
ATOM   6067 H HE1  . HIS A 1 385 ? 24.235  25.760  -28.743 1.000 21.240 0 412  HIS A HE1  1 c 
ATOM   6068 H HE2  . HIS A 1 385 ? 25.554  26.636  -27.007 0.000 20.360 0 412  HIS A HE2  1 c 
ATOM   6069 N N    . LEU A 1 386 ? 19.166  30.476  -26.317 1.000 14.506 0 413  LEU A N    1 ? 
ATOM   6070 C CA   . LEU A 1 386 ? 17.951  31.098  -25.805 1.000 15.105 0 413  LEU A CA   1 ? 
ATOM   6071 C C    . LEU A 1 386 ? 16.848  31.085  -26.861 1.000 15.828 0 413  LEU A C    1 ? 
ATOM   6072 O O    . LEU A 1 386 ? 15.702  30.746  -26.586 1.000 14.398 0 413  LEU A O    1 ? 
ATOM   6073 C CB   . LEU A 1 386 ? 18.187  32.533  -25.319 1.000 13.767 0 413  LEU A CB   1 ? 
ATOM   6074 C CG   . LEU A 1 386 ? 16.983  33.231  -24.671 1.000 15.361 0 413  LEU A CG   1 ? 
ATOM   6075 C CD1  . LEU A 1 386 ? 16.598  32.559  -23.341 1.000 17.878 0 413  LEU A CD1  1 ? 
ATOM   6076 C CD2  . LEU A 1 386 ? 17.339  34.702  -24.550 1.000 16.665 0 413  LEU A CD2  1 ? 
ATOM   6077 H H    . LEU A 1 386 ? 19.950  30.944  -26.268 1.000 14.606 0 413  LEU A H    1 c 
ATOM   6078 H HA   . LEU A 1 386 ? 17.640  30.553  -25.039 1.000 14.889 0 413  LEU A HA   1 c 
ATOM   6079 H HB2  . LEU A 1 386 ? 18.925  32.518  -24.667 1.000 14.420 0 413  LEU A HB2  1 c 
ATOM   6080 H HB3  . LEU A 1 386 ? 18.482  33.072  -26.088 1.000 14.445 0 413  LEU A HB3  1 c 
ATOM   6081 H HG   . LEU A 1 386 ? 16.210  33.155  -25.287 1.000 15.720 0 413  LEU A HG   1 c 
ATOM   6082 H HD11 . LEU A 1 386 ? 16.279  31.658  -23.512 1.000 17.070 0 413  LEU A HD11 1 c 
ATOM   6083 H HD12 . LEU A 1 386 ? 15.896  33.074  -22.909 1.000 17.073 0 413  LEU A HD12 1 c 
ATOM   6084 H HD13 . LEU A 1 386 ? 17.376  32.522  -22.759 1.000 17.090 0 413  LEU A HD13 1 c 
ATOM   6085 H HD21 . LEU A 1 386 ? 17.471  35.080  -25.436 1.000 16.255 0 413  LEU A HD21 1 c 
ATOM   6086 H HD22 . LEU A 1 386 ? 18.157  34.798  -24.033 1.000 16.265 0 413  LEU A HD22 1 c 
ATOM   6087 H HD23 . LEU A 1 386 ? 16.617  35.175  -24.102 1.000 16.265 0 413  LEU A HD23 1 c 
ATOM   6088 N N    . LEU A 1 387 ? 17.212  31.461  -28.103 1.000 15.252 0 414  LEU A N    1 ? 
ATOM   6089 C CA   . LEU A 1 387 ? 16.208  31.497  -29.158 1.000 15.498 0 414  LEU A CA   1 ? 
ATOM   6090 C C    . LEU A 1 387 ? 15.716  30.100  -29.523 1.000 14.192 0 414  LEU A C    1 ? 
ATOM   6091 O O    . LEU A 1 387 ? 14.526  29.923  -29.736 1.000 15.285 0 414  LEU A O    1 ? 
ATOM   6092 C CB   . LEU A 1 387 ? 16.768  32.180  -30.397 1.000 15.557 0 414  LEU A CB   1 ? 
ATOM   6093 C CG   . LEU A 1 387 ? 17.175  33.652  -30.246 1.000 18.582 0 414  LEU A CG   1 ? 
ATOM   6094 C CD1  . LEU A 1 387 ? 17.700  34.186  -31.593 1.000 19.371 0 414  LEU A CD1  1 ? 
ATOM   6095 C CD2  . LEU A 1 387 ? 16.058  34.482  -29.719 1.000 19.852 0 414  LEU A CD2  1 ? 
ATOM   6096 H H    . LEU A 1 387 ? 18.075  31.697  -28.288 1.000 15.455 0 414  LEU A H    1 c 
ATOM   6097 H HA   . LEU A 1 387 ? 15.433  32.018  -28.827 1.000 15.256 0 414  LEU A HA   1 c 
ATOM   6098 H HB2  . LEU A 1 387 ? 17.556  31.671  -30.696 1.000 16.249 0 414  LEU A HB2  1 c 
ATOM   6099 H HB3  . LEU A 1 387 ? 16.093  32.120  -31.111 1.000 16.196 0 414  LEU A HB3  1 c 
ATOM   6100 H HG   . LEU A 1 387 ? 17.918  33.699  -29.593 1.000 18.316 0 414  LEU A HG   1 c 
ATOM   6101 H HD11 . LEU A 1 387 ? 18.515  33.716  -31.833 1.000 19.133 0 414  LEU A HD11 1 c 
ATOM   6102 H HD12 . LEU A 1 387 ? 17.886  35.137  -31.516 1.000 19.117 0 414  LEU A HD12 1 c 
ATOM   6103 H HD13 . LEU A 1 387 ? 17.029  34.044  -32.282 1.000 19.133 0 414  LEU A HD13 1 c 
ATOM   6104 H HD21 . LEU A 1 387 ? 15.920  34.283  -28.777 1.000 19.404 0 414  LEU A HD21 1 c 
ATOM   6105 H HD22 . LEU A 1 387 ? 15.245  34.286  -30.214 1.000 19.447 0 414  LEU A HD22 1 c 
ATOM   6106 H HD23 . LEU A 1 387 ? 16.278  35.424  -29.819 1.000 19.444 0 414  LEU A HD23 1 c 
ATOM   6107 N N    . ARG A 1 388 ? 16.612  29.115  -29.512 1.000 14.815 0 415  ARG A N    1 ? 
ATOM   6108 C CA   . ARG A 1 388 ? 16.236  27.736  -29.803 1.000 15.233 0 415  ARG A CA   1 ? 
ATOM   6109 C C    . ARG A 1 388 ? 15.285  27.156  -28.754 1.000 15.482 0 415  ARG A C    1 ? 
ATOM   6110 O O    . ARG A 1 388 ? 14.334  26.424  -29.089 1.000 16.054 0 415  ARG A O    1 ? 
ATOM   6111 C CB   . ARG A 1 388 ? 17.457  26.842  -29.983 1.000 16.443 0 415  ARG A CB   1 ? 
ATOM   6112 C CG   . ARG A 1 388 ? 17.085  25.439  -30.442 1.000 22.158 0 415  ARG A CG   1 ? 
ATOM   6113 C CD   . ARG A 1 388 ? 18.277  24.719  -31.112 1.000 23.699 0 415  ARG A CD   1 ? 
ATOM   6114 N NE   . ARG A 1 388 ? 19.440  24.487  -30.258 1.000 25.139 0 415  ARG A NE   1 ? 
ATOM   6115 C CZ   . ARG A 1 388 ? 19.693  23.421  -29.453 1.000 23.860 0 415  ARG A CZ   1 ? 
ATOM   6116 N NH1  . ARG A 1 388 ? 18.789  22.485  -29.260 1.000 25.268 0 415  ARG A NH1  1 ? 
ATOM   6117 N NH2  . ARG A 1 388 ? 20.846  23.375  -28.791 1.000 29.498 0 415  ARG A NH2  1 ? 
ATOM   6118 H H    . ARG A 1 388 ? 17.486  29.302  -29.325 1.000 14.775 0 415  ARG A H    1 c 
ATOM   6119 H HA   . ARG A 1 388 ? 15.754  27.739  -30.670 1.000 15.437 0 415  ARG A HA   1 c 
ATOM   6120 H HB2  . ARG A 1 388 ? 18.056  27.247  -30.646 1.000 17.333 0 415  ARG A HB2  1 c 
ATOM   6121 H HB3  . ARG A 1 388 ? 17.941  26.784  -29.133 1.000 17.299 0 415  ARG A HB3  1 c 
ATOM   6122 H HG2  . ARG A 1 388 ? 16.788  24.912  -29.668 1.000 20.976 0 415  ARG A HG2  1 c 
ATOM   6123 H HG3  . ARG A 1 388 ? 16.341  25.490  -31.080 1.000 20.996 0 415  ARG A HG3  1 c 
ATOM   6124 H HD2  . ARG A 1 388 ? 17.959  23.858  -31.453 1.000 23.684 0 415  ARG A HD2  1 c 
ATOM   6125 H HD3  . ARG A 1 388 ? 18.556  25.251  -31.885 1.000 23.678 0 415  ARG A HD3  1 c 
ATOM   6126 H HE   . ARG A 1 388 ? 20.050  25.110  -30.263 1.000 24.549 0 415  ARG A HE   1 c 
ATOM   6127 H HH11 . ARG A 1 388 ? 19.043  21.638  -29.202 1.000 24.845 0 415  ARG A HH11 1 c 
ATOM   6128 H HH12 . ARG A 1 388 ? 17.933  22.706  -29.185 1.000 24.824 0 415  ARG A HH12 1 c 
ATOM   6129 H HH21 . ARG A 1 388 ? 21.019  22.689  -28.262 1.000 27.578 0 415  ARG A HH21 1 c 
ATOM   6130 H HH22 . ARG A 1 388 ? 21.436  24.028  -28.880 1.000 27.572 0 415  ARG A HH22 1 c 
ATOM   6131 N N    . PHE A 1 389 ? 15.499  27.531  -27.498 1.000 14.440 0 416  PHE A N    1 ? 
ATOM   6132 C CA   . PHE A 1 389 ? 14.609  27.195  -26.398 1.000 14.105 0 416  PHE A CA   1 ? 
ATOM   6133 C C    . PHE A 1 389 ? 13.197  27.703  -26.665 1.000 15.069 0 416  PHE A C    1 ? 
ATOM   6134 O O    . PHE A 1 389 ? 12.250  26.936  -26.614 1.000 16.433 0 416  PHE A O    1 ? 
ATOM   6135 C CB   . PHE A 1 389 ? 15.190  27.737  -25.093 1.000 14.559 0 416  PHE A CB   1 ? 
ATOM   6136 C CG   . PHE A 1 389 ? 14.316  27.590  -23.872 1.000 14.771 0 416  PHE A CG   1 ? 
ATOM   6137 C CD1  . PHE A 1 389 ? 14.185  26.368  -23.217 1.000 15.679 0 416  PHE A CD1  1 ? 
ATOM   6138 C CD2  . PHE A 1 389 ? 13.698  28.694  -23.323 1.000 15.707 0 416  PHE A CD2  1 ? 
ATOM   6139 C CE1  . PHE A 1 389 ? 13.398  26.267  -22.088 1.000 15.002 0 416  PHE A CE1  1 ? 
ATOM   6140 C CE2  . PHE A 1 389 ? 12.938  28.612  -22.177 1.000 16.116 0 416  PHE A CE2  1 ? 
ATOM   6141 C CZ   . PHE A 1 389 ? 12.804  27.398  -21.547 1.000 16.422 0 416  PHE A CZ   1 ? 
ATOM   6142 H H    . PHE A 1 389 ? 16.249  28.017  -27.311 1.000 14.608 0 416  PHE A H    1 c 
ATOM   6143 H HA   . PHE A 1 389 ? 14.571  26.205  -26.329 1.000 14.462 0 416  PHE A HA   1 c 
ATOM   6144 H HB2  . PHE A 1 389 ? 16.042  27.277  -24.924 1.000 14.505 0 416  PHE A HB2  1 c 
ATOM   6145 H HB3  . PHE A 1 389 ? 15.395  28.688  -25.219 1.000 14.516 0 416  PHE A HB3  1 c 
ATOM   6146 H HD1  . PHE A 1 389 ? 14.600  25.600  -23.572 1.000 15.322 0 416  PHE A HD1  1 c 
ATOM   6147 H HD2  . PHE A 1 389 ? 13.808  29.533  -23.742 1.000 15.568 0 416  PHE A HD2  1 c 
ATOM   6148 H HE1  . PHE A 1 389 ? 13.307  25.434  -21.653 1.000 15.480 0 416  PHE A HE1  1 c 
ATOM   6149 H HE2  . PHE A 1 389 ? 12.515  29.381  -21.830 1.000 16.057 0 416  PHE A HE2  1 c 
ATOM   6150 H HZ   . PHE A 1 389 ? 12.261  27.324  -20.779 1.000 15.996 0 416  PHE A HZ   1 c 
ATOM   6151 N N    . TYR A 1 390 ? 13.056  28.999  -26.950 1.000 14.418 0 417  TYR A N    1 ? 
ATOM   6152 C CA   . TYR A 1 390 ? 11.744  29.537  -27.256 1.000 14.354 0 417  TYR A CA   1 ? 
ATOM   6153 C C    . TYR A 1 390 ? 11.168  28.922  -28.534 1.000 14.974 0 417  TYR A C    1 ? 
ATOM   6154 O O    . TYR A 1 390 ? 9.940   28.720  -28.602 1.000 15.951 0 417  TYR A O    1 ? 
ATOM   6155 C CB   . TYR A 1 390 ? 11.741  31.078  -27.348 1.000 14.868 0 417  TYR A CB   1 ? 
ATOM   6156 C CG   . TYR A 1 390 ? 11.699  31.730  -25.971 1.000 14.680 0 417  TYR A CG   1 ? 
ATOM   6157 C CD1  . TYR A 1 390 ? 10.485  31.953  -25.350 1.000 15.152 0 417  TYR A CD1  1 ? 
ATOM   6158 C CD2  . TYR A 1 390 ? 12.854  32.083  -25.281 1.000 14.264 0 417  TYR A CD2  1 ? 
ATOM   6159 C CE1  . TYR A 1 390 ? 10.417  32.471  -24.078 1.000 16.174 0 417  TYR A CE1  1 ? 
ATOM   6160 C CE2  . TYR A 1 390 ? 12.798  32.623  -24.019 1.000 13.545 0 417  TYR A CE2  1 ? 
ATOM   6161 C CZ   . TYR A 1 390 ? 11.577  32.805  -23.396 1.000 14.520 0 417  TYR A CZ   1 ? 
ATOM   6162 O OH   . TYR A 1 390 ? 11.475  33.380  -22.162 1.000 16.518 0 417  TYR A OH   1 ? 
ATOM   6163 H H    . TYR A 1 390 ? 13.783  29.554  -26.954 1.000 14.556 0 417  TYR A H    1 c 
ATOM   6164 H HA   . TYR A 1 390 ? 11.141  29.285  -26.507 1.000 14.584 0 417  TYR A HA   1 c 
ATOM   6165 H HB2  . TYR A 1 390 ? 12.551  31.371  -27.821 1.000 14.708 0 417  TYR A HB2  1 c 
ATOM   6166 H HB3  . TYR A 1 390 ? 10.955  31.365  -27.865 1.000 14.710 0 417  TYR A HB3  1 c 
ATOM   6167 H HD1  . TYR A 1 390 ? 9.688   31.695  -25.786 1.000 15.256 0 417  TYR A HD1  1 c 
ATOM   6168 H HD2  . TYR A 1 390 ? 13.695  31.935  -25.681 1.000 14.210 0 417  TYR A HD2  1 c 
ATOM   6169 H HE1  . TYR A 1 390 ? 9.579   32.618  -23.674 1.000 15.514 0 417  TYR A HE1  1 c 
ATOM   6170 H HE2  . TYR A 1 390 ? 13.593  32.857  -23.570 1.000 13.993 0 417  TYR A HE2  1 c 
ATOM   6171 H HH   . TYR A 1 390 ? 11.464  32.772  -21.558 0.000 16.490 0 417  TYR A HH   1 c 
ATOM   6172 N N    . ASP A 1 391 ? 11.991  28.672  -29.556 1.000 14.544 0 418  ASP A N    1 ? 
ATOM   6173 C CA   . ASP A 1 391 ? 11.491  28.055  -30.788 1.000 14.736 0 418  ASP A CA   1 ? 
ATOM   6174 C C    . ASP A 1 391 ? 10.820  26.707  -30.518 1.000 17.038 0 418  ASP A C    1 ? 
ATOM   6175 O O    . ASP A 1 391 ? 9.753   26.390  -31.044 1.000 15.068 0 418  ASP A O    1 ? 
ATOM   6176 C CB   . ASP A 1 391 ? 12.604  27.939  -31.809 1.000 16.046 0 418  ASP A CB   1 ? 
ATOM   6177 C CG   . ASP A 1 391 ? 12.121  27.459  -33.165 1.000 15.931 0 418  ASP A CG   1 ? 
ATOM   6178 O OD1  . ASP A 1 391 ? 11.199  28.111  -33.713 1.000 15.345 0 418  ASP A OD1  1 ? 
ATOM   6179 O OD2  . ASP A 1 391 ? 12.707  26.475  -33.654 1.000 15.944 0 418  ASP A OD2  1 ? 
ATOM   6180 H H    . ASP A 1 391 ? 12.876  28.891  -29.494 1.000 14.693 0 418  ASP A H    1 c 
ATOM   6181 H HA   . ASP A 1 391 ? 10.814  28.654  -31.170 1.000 15.351 0 418  ASP A HA   1 c 
ATOM   6182 H HB2  . ASP A 1 391 ? 13.027  28.816  -31.922 1.000 15.712 0 418  ASP A HB2  1 c 
ATOM   6183 H HB3  . ASP A 1 391 ? 13.280  27.313  -31.476 1.000 15.713 0 418  ASP A HB3  1 c 
ATOM   6184 N N    . GLY A 1 392 ? 11.452  25.891  -29.680 1.000 15.374 0 419  GLY A N    1 ? 
ATOM   6185 C CA   . GLY A 1 392 ? 10.906  24.558  -29.427 1.000 15.538 0 419  GLY A CA   1 ? 
ATOM   6186 C C    . GLY A 1 392 ? 9.570   24.636  -28.689 1.000 16.126 0 419  GLY A C    1 ? 
ATOM   6187 O O    . GLY A 1 392 ? 8.653   23.851  -28.943 1.000 15.735 0 419  GLY A O    1 ? 
ATOM   6188 H H    . GLY A 1 392 ? 12.224  26.151  -29.264 1.000 15.778 0 419  GLY A H    1 c 
ATOM   6189 H HA2  . GLY A 1 392 ? 10.782  24.091  -30.287 1.000 15.633 0 419  GLY A HA2  1 c 
ATOM   6190 H HA3  . GLY A 1 392 ? 11.551  24.042  -28.891 1.000 15.637 0 419  GLY A HA3  1 c 
ATOM   6191 N N    . ILE A 1 393 ? 9.471   25.574  -27.741 1.000 15.226 0 420  ILE A N    1 ? 
ATOM   6192 C CA   . ILE A 1 393 ? 8.253   25.781  -26.987 1.000 14.293 0 420  ILE A CA   1 ? 
ATOM   6193 C C    . ILE A 1 393 ? 7.140   26.226  -27.940 1.000 15.393 0 420  ILE A C    1 ? 
ATOM   6194 O O    . ILE A 1 393 ? 6.009   25.715  -27.889 1.000 15.001 0 420  ILE A O    1 ? 
ATOM   6195 C CB   . ILE A 1 393 ? 8.507   26.717  -25.804 1.000 16.182 0 420  ILE A CB   1 ? 
ATOM   6196 C CG1  . ILE A 1 393 ? 9.460   26.074  -24.800 1.000 18.137 0 420  ILE A CG1  1 ? 
ATOM   6197 C CG2  . ILE A 1 393 ? 7.193   27.081  -25.152 1.000 15.540 0 420  ILE A CG2  1 ? 
ATOM   6198 C CD1  . ILE A 1 393 ? 9.953   27.027  -23.708 1.000 18.639 0 420  ILE A CD1  1 ? 
ATOM   6199 H H    . ILE A 1 393 ? 10.194  26.104  -27.560 1.000 15.263 0 420  ILE A H    1 c 
ATOM   6200 H HA   . ILE A 1 393 ? 7.991   24.915  -26.618 1.000 15.020 0 420  ILE A HA   1 c 
ATOM   6201 H HB   . ILE A 1 393 ? 8.923   27.535  -26.142 1.000 16.026 0 420  ILE A HB   1 c 
ATOM   6202 H HG12 . ILE A 1 393 ? 9.004   25.319  -24.375 1.000 17.772 0 420  ILE A HG12 1 c 
ATOM   6203 H HG13 . ILE A 1 393 ? 10.235  25.721  -25.282 1.000 17.740 0 420  ILE A HG13 1 c 
ATOM   6204 H HG21 . ILE A 1 393 ? 7.358   27.599  -24.347 1.000 15.760 0 420  ILE A HG21 1 c 
ATOM   6205 H HG22 . ILE A 1 393 ? 6.709   26.270  -24.919 1.000 15.735 0 420  ILE A HG22 1 c 
ATOM   6206 H HG23 . ILE A 1 393 ? 6.657   27.609  -25.767 1.000 15.733 0 420  ILE A HG23 1 c 
ATOM   6207 H HD11 . ILE A 1 393 ? 10.340  27.823  -24.120 1.000 18.475 0 420  ILE A HD11 1 c 
ATOM   6208 H HD12 . ILE A 1 393 ? 10.633  26.577  -23.172 1.000 18.467 0 420  ILE A HD12 1 c 
ATOM   6209 H HD13 . ILE A 1 393 ? 9.210   27.288  -23.133 1.000 18.435 0 420  ILE A HD13 1 c 
ATOM   6210 N N    . CYS A 1 394 ? 7.475   27.156  -28.832 1.000 15.131 0 421  CYS A N    1 ? 
ATOM   6211 C CA   . CYS A 1 394 ? 6.478   27.630  -29.782 1.000 15.691 0 421  CYS A CA   1 ? 
ATOM   6212 C C    . CYS A 1 394 ? 6.058   26.496  -30.718 1.000 15.970 0 421  CYS A C    1 ? 
ATOM   6213 O O    . CYS A 1 394 ? 4.892   26.400  -31.084 1.000 17.163 0 421  CYS A O    1 ? 
ATOM   6214 C CB   . CYS A 1 394 ? 7.009   28.785  -30.651 1.000 15.528 0 421  CYS A CB   1 ? 
ATOM   6215 S SG   . CYS A 1 394 ? 7.221   30.341  -29.738 1.000 17.175 0 421  CYS A SG   1 ? 
ATOM   6216 H H    . CYS A 1 394 ? 8.320   27.505  -28.851 1.000 15.311 0 421  CYS A H    1 c 
ATOM   6217 H HA   . CYS A 1 394 ? 5.683   27.936  -29.274 1.000 15.597 0 421  CYS A HA   1 c 
ATOM   6218 H HB2  . CYS A 1 394 ? 7.878   28.527  -31.031 1.000 15.867 0 421  CYS A HB2  1 c 
ATOM   6219 H HB3  . CYS A 1 394 ? 6.387   28.943  -31.395 1.000 15.867 0 421  CYS A HB3  1 c 
ATOM   6220 H HG   . CYS A 1 394 ? 7.629   31.012  -30.659 0.000 17.180 0 421  CYS A HG   1 c 
ATOM   6221 N N    . LYS A 1 395 ? 6.993   25.642  -31.144 1.000 15.365 0 422  LYS A N    1 ? 
ATOM   6222 C CA   . LYS A 1 395 ? 6.669   24.534  -32.061 1.000 15.125 0 422  LYS A CA   1 ? 
ATOM   6223 C C    . LYS A 1 395 ? 5.774   23.516  -31.367 1.000 17.240 0 422  LYS A C    1 ? 
ATOM   6224 O O    . LYS A 1 395 ? 4.843   22.953  -31.956 1.000 17.607 0 422  LYS A O    1 ? 
ATOM   6225 C CB   . LYS A 1 395 ? 7.925   23.922  -32.660 1.000 17.016 0 422  LYS A CB   1 ? 
ATOM   6226 C CG   . LYS A 1 395 ? 7.701   22.780  -33.639 1.000 20.668 0 422  LYS A CG   1 ? 
ATOM   6227 C CD   . LYS A 1 395 ? 6.975   23.117  -34.917 1.000 26.005 0 422  LYS A CD   1 ? 
ATOM   6228 C CE   . LYS A 1 395 ? 7.019   21.826  -35.765 1.000 33.411 0 422  LYS A CE   1 ? 
ATOM   6229 N NZ   . LYS A 1 395 ? 6.399   22.029  -37.065 1.000 44.279 0 422  LYS A NZ   1 ? 
ATOM   6230 H H    . LYS A 1 395 ? 7.858   25.745  -30.867 1.000 15.462 0 422  LYS A H    1 c 
ATOM   6231 H HA   . LYS A 1 395 ? 6.153   24.917  -32.816 1.000 15.929 0 422  LYS A HA   1 c 
ATOM   6232 H HB2  . LYS A 1 395 ? 8.423   24.629  -33.123 1.000 17.322 0 422  LYS A HB2  1 c 
ATOM   6233 H HB3  . LYS A 1 395 ? 8.490   23.597  -31.928 1.000 17.331 0 422  LYS A HB3  1 c 
ATOM   6234 H HG2  . LYS A 1 395 ? 8.579   22.406  -33.870 1.000 20.970 0 422  LYS A HG2  1 c 
ATOM   6235 H HG3  . LYS A 1 395 ? 7.202   22.072  -33.176 1.000 20.852 0 422  LYS A HG3  1 c 
ATOM   6236 H HD2  . LYS A 1 395 ? 6.044   23.364  -34.730 1.000 26.094 0 422  LYS A HD2  1 c 
ATOM   6237 H HD3  . LYS A 1 395 ? 7.432   23.845  -35.391 1.000 26.094 0 422  LYS A HD3  1 c 
ATOM   6238 H HE2  . LYS A 1 395 ? 7.943   21.548  -35.896 1.000 33.621 0 422  LYS A HE2  1 c 
ATOM   6239 H HE3  . LYS A 1 395 ? 6.550   21.112  -35.297 1.000 33.786 0 422  LYS A HE3  1 c 
ATOM   6240 H HZ1  . LYS A 1 395 ? 6.838   22.682  -37.515 1.000 40.592 0 422  LYS A HZ1  1 c 
ATOM   6241 H HZ2  . LYS A 1 395 ? 5.533   22.273  -36.957 1.000 40.592 0 422  LYS A HZ2  1 c 
ATOM   6242 H HZ3  . LYS A 1 395 ? 6.435   21.261  -37.544 1.000 40.592 0 422  LYS A HZ3  1 c 
ATOM   6243 N N    . TRP A 1 396 ? 6.098   23.203  -30.114 1.000 16.232 0 423  TRP A N    1 ? 
ATOM   6244 C CA   . TRP A 1 396 ? 5.274   22.371  -29.236 1.000 16.877 0 423  TRP A CA   1 ? 
ATOM   6245 C C    . TRP A 1 396 ? 3.814   22.761  -29.299 1.000 17.037 0 423  TRP A C    1 ? 
ATOM   6246 O O    . TRP A 1 396 ? 2.948   21.913  -29.513 1.000 19.732 0 423  TRP A O    1 ? 
ATOM   6247 C CB   . TRP A 1 396 ? 5.825   22.482  -27.805 1.000 16.323 0 423  TRP A CB   1 ? 
ATOM   6248 C CG   . TRP A 1 396 ? 5.167   21.699  -26.717 1.000 17.001 0 423  TRP A CG   1 ? 
ATOM   6249 C CD1  . TRP A 1 396 ? 4.552   20.480  -26.826 1.000 17.939 0 423  TRP A CD1  1 ? 
ATOM   6250 C CD2  . TRP A 1 396 ? 5.221   22.009  -25.314 1.000 16.350 0 423  TRP A CD2  1 ? 
ATOM   6251 N NE1  . TRP A 1 396 ? 4.177   20.031  -25.578 1.000 19.907 0 423  TRP A NE1  1 ? 
ATOM   6252 C CE2  . TRP A 1 396 ? 4.585   20.949  -24.635 1.000 17.967 0 423  TRP A CE2  1 ? 
ATOM   6253 C CE3  . TRP A 1 396 ? 5.768   23.067  -24.580 1.000 18.216 0 423  TRP A CE3  1 ? 
ATOM   6254 C CZ2  . TRP A 1 396 ? 4.475   20.909  -23.255 1.000 20.777 0 423  TRP A CZ2  1 ? 
ATOM   6255 C CZ3  . TRP A 1 396 ? 5.622   23.064  -23.215 1.000 19.370 0 423  TRP A CZ3  1 ? 
ATOM   6256 C CH2  . TRP A 1 396 ? 5.016   21.981  -22.560 1.000 20.607 0 423  TRP A CH2  1 ? 
ATOM   6257 H H    . TRP A 1 396 ? 6.889   23.520  -29.783 1.000 16.591 0 423  TRP A H    1 c 
ATOM   6258 H HA   . TRP A 1 396 ? 5.362   21.425  -29.531 1.000 16.695 0 423  TRP A HA   1 c 
ATOM   6259 H HB2  . TRP A 1 396 ? 6.773   22.233  -27.830 1.000 16.598 0 423  TRP A HB2  1 c 
ATOM   6260 H HB3  . TRP A 1 396 ? 5.809   23.428  -27.550 1.000 16.592 0 423  TRP A HB3  1 c 
ATOM   6261 H HD1  . TRP A 1 396 ? 4.376   20.025  -27.633 1.000 18.152 0 423  TRP A HD1  1 c 
ATOM   6262 H HE1  . TRP A 1 396 ? 3.744   19.291  -25.414 1.000 18.944 0 423  TRP A HE1  1 c 
ATOM   6263 H HE3  . TRP A 1 396 ? 6.177   23.793  -25.019 1.000 18.063 0 423  TRP A HE3  1 c 
ATOM   6264 H HZ2  . TRP A 1 396 ? 4.049   20.194  -22.813 1.000 20.017 0 423  TRP A HZ2  1 c 
ATOM   6265 H HZ3  . TRP A 1 396 ? 5.988   23.768  -22.706 1.000 19.346 0 423  TRP A HZ3  1 c 
ATOM   6266 H HH2  . TRP A 1 396 ? 4.942   21.999  -21.623 1.000 20.253 0 423  TRP A HH2  1 c 
ATOM   6267 N N    . GLU A 1 397 ? 3.553   24.049  -29.154 1.000 17.231 0 424  GLU A N    1 ? 
ATOM   6268 C CA   . GLU A 1 397 ? 2.217   24.588  -29.088 1.000 19.517 0 424  GLU A CA   1 ? 
ATOM   6269 C C    . GLU A 1 397 ? 1.480   24.382  -30.421 1.000 18.650 0 424  GLU A C    1 ? 
ATOM   6270 O O    . GLU A 1 397 ? 0.272   24.229  -30.400 1.000 21.556 0 424  GLU A O    1 ? 
ATOM   6271 C CB   . GLU A 1 397 ? 2.359   26.062  -28.758 1.000 19.403 0 424  GLU A CB   1 ? 
ATOM   6272 C CG   . GLU A 1 397 ? 1.055   26.826  -28.784 1.000 23.120 0 424  GLU A CG   1 ? 
ATOM   6273 C CD   . GLU A 1 397 ? 1.279   28.259  -28.428 1.000 23.603 0 424  GLU A CD   1 ? 
ATOM   6274 O OE1  . GLU A 1 397 ? 1.854   29.049  -29.256 1.000 21.494 0 424  GLU A OE1  1 ? 
ATOM   6275 O OE2  . GLU A 1 397 ? 0.767   28.603  -27.365 1.000 23.964 0 424  GLU A OE2  1 ? 
ATOM   6276 H H    . GLU A 1 397 ? 4.257   24.629  -29.088 1.000 17.697 0 424  GLU A H    1 c 
ATOM   6277 H HA   . GLU A 1 397 ? 1.722   24.126  -28.365 1.000 18.870 0 424  GLU A HA   1 c 
ATOM   6278 H HB2  . GLU A 1 397 ? 2.760   26.148  -27.868 1.000 20.248 0 424  GLU A HB2  1 c 
ATOM   6279 H HB3  . GLU A 1 397 ? 2.971   26.473  -29.402 1.000 20.214 0 424  GLU A HB3  1 c 
ATOM   6280 H HG2  . GLU A 1 397 ? 0.662   26.780  -29.681 1.000 22.304 0 424  GLU A HG2  1 c 
ATOM   6281 H HG3  . GLU A 1 397 ? 0.426   26.428  -28.146 1.000 22.340 0 424  GLU A HG3  1 c 
ATOM   6282 N N    . GLU A 1 398 ? 2.180   24.349  -31.553 1.000 18.455 0 425  GLU A N    1 ? 
ATOM   6283 C CA   . GLU A 1 398 ? 1.560   24.192  -32.873 1.000 20.923 0 425  GLU A CA   1 ? 
ATOM   6284 C C    . GLU A 1 398 ? 0.823   22.851  -32.963 1.000 26.190 0 425  GLU A C    1 ? 
ATOM   6285 O O    . GLU A 1 398 ? 1.404   21.777  -32.732 1.000 26.960 0 425  GLU A O    1 ? 
ATOM   6286 C CB   . GLU A 1 398 ? 2.520   24.293  -34.065 1.000 20.187 0 425  GLU A CB   1 ? 
ATOM   6287 C CG   . GLU A 1 398 ? 3.187   25.658  -34.113 1.000 20.004 0 425  GLU A CG   1 ? 
ATOM   6288 C CD   . GLU A 1 398 ? 4.062   25.851  -35.324 1.000 22.488 0 425  GLU A CD   1 ? 
ATOM   6289 O OE1  . GLU A 1 398 ? 4.061   24.960  -36.212 1.000 22.665 0 425  GLU A OE1  1 ? 
ATOM   6290 O OE2  . GLU A 1 398 ? 4.807   26.836  -35.347 1.000 20.441 0 425  GLU A OE2  1 ? 
ATOM   6291 H H    . GLU A 1 398 ? 3.088   24.436  -31.511 1.000 19.016 0 425  GLU A H    1 c 
ATOM   6292 H HA   . GLU A 1 398 ? 0.893   24.917  -32.975 1.000 21.197 0 425  GLU A HA   1 c 
ATOM   6293 H HB2  . GLU A 1 398 ? 3.201   23.592  -33.990 1.000 20.302 0 425  GLU A HB2  1 c 
ATOM   6294 H HB3  . GLU A 1 398 ? 2.018   24.140  -34.893 1.000 20.347 0 425  GLU A HB3  1 c 
ATOM   6295 H HG2  . GLU A 1 398 ? 2.496   26.355  -34.110 1.000 20.586 0 425  GLU A HG2  1 c 
ATOM   6296 H HG3  . GLU A 1 398 ? 3.736   25.776  -33.309 1.000 20.553 0 425  GLU A HG3  1 c 
ATOM   6297 N N    . GLY A 1 399 ? -0.473  22.960  -33.299 1.000 25.264 0 426  GLY A N    1 ? 
ATOM   6298 C CA   . GLY A 1 399 ? -1.322  21.792  -33.500 1.000 31.368 0 426  GLY A CA   1 ? 
ATOM   6299 C C    . GLY A 1 399 ? -1.705  21.093  -32.200 1.000 30.446 0 426  GLY A C    1 ? 
ATOM   6300 O O    . GLY A 1 399 ? -2.262  19.993  -32.237 1.000 35.300 0 426  GLY A O    1 ? 
ATOM   6301 H H    . GLY A 1 399 ? -0.840  23.790  -33.408 1.000 26.653 0 426  GLY A H    1 c 
ATOM   6302 H HA2  . GLY A 1 399 ? -2.142  22.075  -33.969 1.000 29.584 0 426  GLY A HA2  1 c 
ATOM   6303 H HA3  . GLY A 1 399 ? -0.849  21.154  -34.084 1.000 29.557 0 426  GLY A HA3  1 c 
ATOM   6304 N N    . SER A 1 400 ? -1.438  21.741  -31.058 1.000 23.996 0 427  SER A N    1 ? 
ATOM   6305 C CA   . SER A 1 400 ? -1.805  21.178  -29.778 1.000 26.468 0 427  SER A CA   1 ? 
ATOM   6306 C C    . SER A 1 400 ? -3.241  21.520  -29.470 1.000 26.328 0 427  SER A C    1 ? 
ATOM   6307 O O    . SER A 1 400 ? -3.748  22.594  -29.811 1.000 29.469 0 427  SER A O    1 ? 
ATOM   6308 C CB   . SER A 1 400 ? -0.922  21.658  -28.641 1.000 25.647 0 427  SER A CB   1 ? 
ATOM   6309 O OG   . SER A 1 400 ? 0.416   21.194  -28.841 1.000 25.461 0 427  SER A OG   1 ? 
ATOM   6310 H H    . SER A 1 400 ? -1.032  22.559  -31.078 1.000 25.996 0 427  SER A H    1 c 
ATOM   6311 H HA   . SER A 1 400 ? -1.722  20.193  -29.841 1.000 25.963 0 427  SER A HA   1 c 
ATOM   6312 H HB2  . SER A 1 400 ? -0.930  22.633  -28.610 1.000 25.758 0 427  SER A HB2  1 c 
ATOM   6313 H HB3  . SER A 1 400 ? -1.264  21.317  -27.794 1.000 25.767 0 427  SER A HB3  1 c 
ATOM   6314 H HG   . SER A 1 400 ? 0.895   21.465  -28.204 0.000 25.450 0 427  SER A HG   1 c 
ATOM   6315 N N    . PRO A 1 401 ? -3.936  20.623  -28.750 1.000 29.260 0 428  PRO A N    1 ? 
ATOM   6316 C CA   . PRO A 1 401 ? -5.327  20.900  -28.417 1.000 30.270 0 428  PRO A CA   1 ? 
ATOM   6317 C C    . PRO A 1 401 ? -5.525  21.988  -27.367 1.000 38.165 0 428  PRO A C    1 ? 
ATOM   6318 O O    . PRO A 1 401 ? -6.632  22.481  -27.232 1.000 36.659 0 428  PRO A O    1 ? 
ATOM   6319 C CB   . PRO A 1 401 ? -5.850  19.514  -28.004 1.000 33.436 0 428  PRO A CB   1 ? 
ATOM   6320 C CG   . PRO A 1 401 ? -4.633  18.799  -27.473 1.000 33.327 0 428  PRO A CG   1 ? 
ATOM   6321 C CD   . PRO A 1 401 ? -3.481  19.276  -28.357 1.000 30.608 0 428  PRO A CD   1 ? 
ATOM   6322 H HA   . PRO A 1 401 ? -5.788  21.174  -29.249 1.000 31.901 0 428  PRO A HA   1 c 
ATOM   6323 H HB2  . PRO A 1 401 ? -6.544  19.592  -27.307 1.000 32.711 0 428  PRO A HB2  1 c 
ATOM   6324 H HB3  . PRO A 1 401 ? -6.228  19.036  -28.779 1.000 32.688 0 428  PRO A HB3  1 c 
ATOM   6325 H HG2  . PRO A 1 401 ? -4.471  19.035  -26.536 1.000 32.722 0 428  PRO A HG2  1 c 
ATOM   6326 H HG3  . PRO A 1 401 ? -4.742  17.828  -27.540 1.000 32.722 0 428  PRO A HG3  1 c 
ATOM   6327 H HD2  . PRO A 1 401 ? -2.638  19.314  -27.855 1.000 30.743 0 428  PRO A HD2  1 c 
ATOM   6328 H HD3  . PRO A 1 401 ? -3.370  18.693  -29.140 1.000 30.808 0 428  PRO A HD3  1 c 
ATOM   6329 N N    . THR A 1 402 ? -4.450  22.376  -26.658 1.000 37.447 0 429  THR A N    1 ? 
ATOM   6330 C CA   . THR A 1 402 ? -4.495  23.437  -25.662 1.000 38.297 0 429  THR A CA   1 ? 
ATOM   6331 C C    . THR A 1 402 ? -3.250  24.300  -25.877 1.000 36.885 0 429  THR A C    1 ? 
ATOM   6332 O O    . THR A 1 402 ? -2.196  23.736  -26.191 1.000 31.171 0 429  THR A O    1 ? 
ATOM   6333 C CB   . THR A 1 402 ? -4.579  22.839  -24.250 1.000 45.010 0 429  THR A CB   1 ? 
ATOM   6334 O OG1  . THR A 1 402 ? -3.625  23.447  -23.389 1.000 54.667 0 429  THR A OG1  1 ? 
ATOM   6335 C CG2  . THR A 1 402 ? -4.238  21.360  -24.141 1.000 45.404 0 429  THR A CG2  1 ? 
ATOM   6336 H H    . THR A 1 402 ? -3.654  21.950  -26.798 1.000 37.633 0 429  THR A H    1 c 
ATOM   6337 H HA   . THR A 1 402 ? -5.294  23.980  -25.822 1.000 38.972 0 429  THR A HA   1 c 
ATOM   6338 H HB   . THR A 1 402 ? -5.484  22.986  -23.886 1.000 45.487 0 429  THR A HB   1 c 
ATOM   6339 H HG1  . THR A 1 402 ? -2.831  23.318  -23.706 0.000 54.870 0 429  THR A HG1  1 c 
ATOM   6340 H HG21 . THR A 1 402 ? -4.286  21.084  -23.210 1.000 45.267 0 429  THR A HG21 1 c 
ATOM   6341 H HG22 . THR A 1 402 ? -3.339  21.210  -24.474 1.000 45.023 0 429  THR A HG22 1 c 
ATOM   6342 H HG23 . THR A 1 402 ? -4.869  20.839  -24.665 1.000 45.186 0 429  THR A HG23 1 c 
ATOM   6343 N N    . PRO A 1 403 ? -3.339  25.651  -25.763 1.000 32.875 0 430  PRO A N    1 ? 
ATOM   6344 C CA   . PRO A 1 403 ? -2.185  26.540  -25.961 1.000 32.489 0 430  PRO A CA   1 ? 
ATOM   6345 C C    . PRO A 1 403 ? -1.149  26.448  -24.841 1.000 27.379 0 430  PRO A C    1 ? 
ATOM   6346 O O    . PRO A 1 403 ? -1.438  25.995  -23.728 1.000 27.066 0 430  PRO A O    1 ? 
ATOM   6347 C CB   . PRO A 1 403 ? -2.805  27.952  -25.982 1.000 35.445 0 430  PRO A CB   1 ? 
ATOM   6348 C CG   . PRO A 1 403 ? -4.283  27.695  -26.176 1.000 38.974 0 430  PRO A CG   1 ? 
ATOM   6349 C CD   . PRO A 1 403 ? -4.535  26.421  -25.406 1.000 38.907 0 430  PRO A CD   1 ? 
ATOM   6350 H HA   . PRO A 1 403 ? -1.762  26.344  -26.835 1.000 32.003 0 430  PRO A HA   1 c 
ATOM   6351 H HB2  . PRO A 1 403 ? -2.638  28.425  -25.132 1.000 35.470 0 430  PRO A HB2  1 c 
ATOM   6352 H HB3  . PRO A 1 403 ? -2.439  28.487  -26.725 1.000 35.515 0 430  PRO A HB3  1 c 
ATOM   6353 H HG2  . PRO A 1 403 ? -4.819  28.432  -25.817 1.000 38.132 0 430  PRO A HG2  1 c 
ATOM   6354 H HG3  . PRO A 1 403 ? -4.497  27.577  -27.125 1.000 38.132 0 430  PRO A HG3  1 c 
ATOM   6355 H HD2  . PRO A 1 403 ? -4.581  26.589  -24.438 1.000 37.433 0 430  PRO A HD2  1 c 
ATOM   6356 H HD3  . PRO A 1 403 ? -5.358  25.981  -25.708 1.000 37.450 0 430  PRO A HD3  1 c 
ATOM   6357 N N    . VAL A 1 404 ? 0.065   26.955  -25.121 1.000 24.057 0 431  VAL A N    1 ? 
ATOM   6358 C CA   . VAL A 1 404 ? 1.139   26.969  -24.147 1.000 20.805 0 431  VAL A CA   1 ? 
ATOM   6359 C C    . VAL A 1 404 ? 1.431   28.411  -23.713 1.000 21.302 0 431  VAL A C    1 ? 
ATOM   6360 O O    . VAL A 1 404 ? 1.490   28.758  -22.525 1.000 20.854 0 431  VAL A O    1 ? 
ATOM   6361 C CB   . VAL A 1 404 ? 2.395   26.305  -24.752 1.000 21.519 0 431  VAL A CB   1 ? 
ATOM   6362 C CG1  . VAL A 1 404 ? 3.602   26.503  -23.832 1.000 22.480 0 431  VAL A CG1  1 ? 
ATOM   6363 C CG2  . VAL A 1 404 ? 2.157   24.838  -25.144 1.000 21.574 0 431  VAL A CG2  1 ? 
ATOM   6364 H H    . VAL A 1 404 ? 0.223   27.297  -25.953 1.000 24.067 0 431  VAL A H    1 c 
ATOM   6365 H HA   . VAL A 1 404 ? 0.863   26.456  -23.363 1.000 21.690 0 431  VAL A HA   1 c 
ATOM   6366 H HB   . VAL A 1 404 ? 2.594   26.791  -25.586 1.000 21.562 0 431  VAL A HB   1 c 
ATOM   6367 H HG11 . VAL A 1 404 ? 3.362   26.257  -22.924 1.000 22.166 0 431  VAL A HG11 1 c 
ATOM   6368 H HG12 . VAL A 1 404 ? 3.881   27.433  -23.853 1.000 22.182 0 431  VAL A HG12 1 c 
ATOM   6369 H HG13 . VAL A 1 404 ? 4.335   25.940  -24.135 1.000 22.186 0 431  VAL A HG13 1 c 
ATOM   6370 H HG21 . VAL A 1 404 ? 2.983   24.454  -25.483 1.000 21.566 0 431  VAL A HG21 1 c 
ATOM   6371 H HG22 . VAL A 1 404 ? 1.473   24.791  -25.832 1.000 21.576 0 431  VAL A HG22 1 c 
ATOM   6372 H HG23 . VAL A 1 404 ? 1.865   24.336  -24.364 1.000 21.582 0 431  VAL A HG23 1 c 
ATOM   6373 N N    . LEU A 1 405 ? 1.667   29.300  -24.694 1.000 21.140 0 432  LEU A N    1 ? 
ATOM   6374 C CA   . LEU A 1 405 ? 2.135   30.638  -24.439 1.000 20.980 0 432  LEU A CA   1 ? 
ATOM   6375 C C    . LEU A 1 405 ? 1.016   31.599  -24.113 1.000 21.594 0 432  LEU A C    1 ? 
ATOM   6376 O O    . LEU A 1 405 ? -0.071  31.482  -24.632 1.000 27.234 0 432  LEU A O    1 ? 
ATOM   6377 C CB   . LEU A 1 405 ? 2.918   31.137  -25.647 1.000 19.214 0 432  LEU A CB   1 ? 
ATOM   6378 C CG   . LEU A 1 405 ? 4.221   30.367  -25.874 1.000 23.816 0 432  LEU A CG   1 ? 
ATOM   6379 C CD1  . LEU A 1 405 ? 4.736   30.502  -27.255 1.000 27.883 0 432  LEU A CD1  1 ? 
ATOM   6380 C CD2  . LEU A 1 405 ? 5.334   30.762  -24.901 1.000 25.261 0 432  LEU A CD2  1 ? 
ATOM   6381 H H    . LEU A 1 405 ? 1.530   29.046  -25.561 1.000 21.163 0 432  LEU A H    1 c 
ATOM   6382 H HA   . LEU A 1 405 ? 2.745   30.601  -23.660 1.000 20.833 0 432  LEU A HA   1 c 
ATOM   6383 H HB2  . LEU A 1 405 ? 2.352   31.047  -26.448 1.000 20.655 0 432  LEU A HB2  1 c 
ATOM   6384 H HB3  . LEU A 1 405 ? 3.133   32.089  -25.510 1.000 20.602 0 432  LEU A HB3  1 c 
ATOM   6385 H HG   . LEU A 1 405 ? 4.031   29.405  -25.727 1.000 23.842 0 432  LEU A HG   1 c 
ATOM   6386 H HD11 . LEU A 1 405 ? 4.060   30.201  -27.885 1.000 26.520 0 432  LEU A HD11 1 c 
ATOM   6387 H HD12 . LEU A 1 405 ? 5.536   29.962  -27.357 1.000 26.500 0 432  LEU A HD12 1 c 
ATOM   6388 H HD13 . LEU A 1 405 ? 4.950   31.434  -27.432 1.000 26.555 0 432  LEU A HD13 1 c 
ATOM   6389 H HD21 . LEU A 1 405 ? 5.049   30.580  -23.991 1.000 24.752 0 432  LEU A HD21 1 c 
ATOM   6390 H HD22 . LEU A 1 405 ? 5.528   31.710  -24.996 1.000 24.815 0 432  LEU A HD22 1 c 
ATOM   6391 H HD23 . LEU A 1 405 ? 6.136   30.248  -25.097 1.000 24.837 0 432  LEU A HD23 1 c 
ATOM   6392 N N    . HIS A 1 406 ? 1.380   32.621  -23.337 1.000 20.716 0 433  HIS A N    1 ? 
ATOM   6393 C CA   . HIS A 1 406 ? 0.505   33.708  -22.938 1.000 21.709 0 433  HIS A CA   1 ? 
ATOM   6394 C C    . HIS A 1 406 ? 1.350   34.925  -22.578 1.000 23.129 0 433  HIS A C    1 ? 
ATOM   6395 O O    . HIS A 1 406 ? 2.580   34.875  -22.577 1.000 21.583 0 433  HIS A O    1 ? 
ATOM   6396 C CB   . HIS A 1 406 ? -0.465  33.259  -21.845 1.000 20.993 0 433  HIS A CB   1 ? 
ATOM   6397 C CG   . HIS A 1 406 ? 0.119   32.899  -20.560 1.000 21.315 0 433  HIS A CG   1 ? 
ATOM   6398 N ND1  . HIS A 1 406 ? 0.790   33.804  -19.801 1.000 19.773 0 433  HIS A ND1  1 ? 
ATOM   6399 C CD2  . HIS A 1 406 ? 0.071   31.784  -19.844 1.000 25.280 0 433  HIS A CD2  1 ? 
ATOM   6400 C CE1  . HIS A 1 406 ? 1.172   33.242  -18.675 1.000 24.709 0 433  HIS A CE1  1 ? 
ATOM   6401 N NE2  . HIS A 1 406 ? 0.741   32.019  -18.671 1.000 22.862 0 433  HIS A NE2  1 ? 
ATOM   6402 H H    . HIS A 1 406 ? 2.244   32.643  -23.039 1.000 21.097 0 433  HIS A H    1 c 
ATOM   6403 H HA   . HIS A 1 406 ? -0.036  33.945  -23.731 1.000 21.657 0 433  HIS A HA   1 c 
ATOM   6404 H HB2  . HIS A 1 406 ? -1.118  33.978  -21.700 1.000 21.239 0 433  HIS A HB2  1 c 
ATOM   6405 H HB3  . HIS A 1 406 ? -0.972  32.489  -22.183 1.000 21.232 0 433  HIS A HB3  1 c 
ATOM   6406 H HD1  . HIS A 1 406 ? 0.926   34.652  -20.012 0.000 19.730 0 433  HIS A HD1  1 c 
ATOM   6407 H HD2  . HIS A 1 406 ? -0.335  30.978  -20.096 1.000 23.714 0 433  HIS A HD2  1 c 
ATOM   6408 H HE1  . HIS A 1 406 ? 1.667   33.655  -17.989 1.000 23.063 0 433  HIS A HE1  1 c 
ATOM   6409 H HE2  . HIS A 1 406 ? 0.873   31.437  -18.028 0.000 22.820 0 433  HIS A HE2  1 c 
ATOM   6410 N N    . VAL A 1 407 ? 0.700   36.072  -22.327 1.000 22.262 0 434  VAL A N    1 ? 
ATOM   6411 C CA   . VAL A 1 407 ? 1.443   37.307  -22.191 1.000 23.231 0 434  VAL A CA   1 ? 
ATOM   6412 C C    . VAL A 1 407 ? 2.386   37.280  -20.982 1.000 24.262 0 434  VAL A C    1 ? 
ATOM   6413 O O    . VAL A 1 407 ? 3.364   38.018  -20.999 1.000 24.281 0 434  VAL A O    1 ? 
ATOM   6414 C CB   . VAL A 1 407 ? 0.548   38.561  -22.212 1.000 29.247 0 434  VAL A CB   1 ? 
ATOM   6415 C CG1  . VAL A 1 407 ? -0.285  38.696  -20.964 1.000 33.647 0 434  VAL A CG1  1 ? 
ATOM   6416 C CG2  . VAL A 1 407 ? 1.397   39.806  -22.388 1.000 33.042 0 434  VAL A CG2  1 ? 
ATOM   6417 H H    . VAL A 1 407 ? -0.210  36.081  -22.243 1.000 22.753 0 434  VAL A H    1 c 
ATOM   6418 H HA   . VAL A 1 407 ? 2.015   37.368  -22.981 1.000 24.315 0 434  VAL A HA   1 c 
ATOM   6419 H HB   . VAL A 1 407 ? -0.057  38.481  -22.987 1.000 29.430 0 434  VAL A HB   1 c 
ATOM   6420 H HG11 . VAL A 1 407 ? 0.293   38.864  -20.201 1.000 32.202 0 434  VAL A HG11 1 c 
ATOM   6421 H HG12 . VAL A 1 407 ? -0.784  37.878  -20.819 1.000 32.178 0 434  VAL A HG12 1 c 
ATOM   6422 H HG13 . VAL A 1 407 ? -0.906  39.438  -21.068 1.000 32.240 0 434  VAL A HG13 1 c 
ATOM   6423 H HG21 . VAL A 1 407 ? 0.827   40.554  -22.631 1.000 31.822 0 434  VAL A HG21 1 c 
ATOM   6424 H HG22 . VAL A 1 407 ? 2.052   39.657  -23.091 1.000 31.730 0 434  VAL A HG22 1 c 
ATOM   6425 H HG23 . VAL A 1 407 ? 1.856   40.009  -21.556 1.000 31.761 0 434  VAL A HG23 1 c 
ATOM   6426 N N    . GLY A 1 408 ? 2.119   36.425  -19.986 1.000 24.950 0 435  GLY A N    1 ? 
ATOM   6427 C CA   . GLY A 1 408 ? 3.021   36.276  -18.845 1.000 27.322 0 435  GLY A CA   1 ? 
ATOM   6428 C C    . GLY A 1 408 ? 4.394   35.798  -19.301 1.000 27.850 0 435  GLY A C    1 ? 
ATOM   6429 O O    . GLY A 1 408 ? 5.439   36.284  -18.870 1.000 31.808 0 435  GLY A O    1 ? 
ATOM   6430 H H    . GLY A 1 408 ? 1.339   35.950  -19.995 1.000 25.191 0 435  GLY A H    1 c 
ATOM   6431 H HA2  . GLY A 1 408 ? 3.108   37.143  -18.385 1.000 26.847 0 435  GLY A HA2  1 c 
ATOM   6432 H HA3  . GLY A 1 408 ? 2.639   35.630  -18.209 1.000 26.815 0 435  GLY A HA3  1 c 
ATOM   6433 N N    . TRP A 1 409 ? 4.402   34.931  -20.312 1.000 19.749 0 436  TRP A N    1 ? 
ATOM   6434 C CA   . TRP A 1 409 ? 5.666   34.504  -20.900 1.000 18.330 0 436  TRP A CA   1 ? 
ATOM   6435 C C    . TRP A 1 409 ? 6.350   35.643  -21.665 1.000 19.170 0 436  TRP A C    1 ? 
ATOM   6436 O O    . TRP A 1 409 ? 7.581   35.676  -21.829 1.000 19.021 0 436  TRP A O    1 ? 
ATOM   6437 C CB   . TRP A 1 409 ? 5.432   33.351  -21.881 1.000 16.763 0 436  TRP A CB   1 ? 
ATOM   6438 C CG   . TRP A 1 409 ? 4.985   32.028  -21.307 1.000 15.704 0 436  TRP A CG   1 ? 
ATOM   6439 C CD1  . TRP A 1 409 ? 3.740   31.652  -20.895 1.000 17.473 0 436  TRP A CD1  1 ? 
ATOM   6440 C CD2  . TRP A 1 409 ? 5.772   30.814  -21.267 1.000 16.277 0 436  TRP A CD2  1 ? 
ATOM   6441 N NE1  . TRP A 1 409 ? 3.702   30.331  -20.549 1.000 16.487 0 436  TRP A NE1  1 ? 
ATOM   6442 C CE2  . TRP A 1 409 ? 4.933   29.778  -20.784 1.000 16.449 0 436  TRP A CE2  1 ? 
ATOM   6443 C CE3  . TRP A 1 409 ? 7.094   30.486  -21.578 1.000 17.665 0 436  TRP A CE3  1 ? 
ATOM   6444 C CZ2  . TRP A 1 409 ? 5.359   28.468  -20.597 1.000 17.346 0 436  TRP A CZ2  1 ? 
ATOM   6445 C CZ3  . TRP A 1 409 ? 7.493   29.176  -21.417 1.000 15.862 0 436  TRP A CZ3  1 ? 
ATOM   6446 C CH2  . TRP A 1 409 ? 6.646   28.176  -20.966 1.000 16.068 0 436  TRP A CH2  1 ? 
ATOM   6447 H H    . TRP A 1 409 ? 3.618   34.591  -20.638 1.000 21.128 0 436  TRP A H    1 c 
ATOM   6448 H HA   . TRP A 1 409 ? 6.270   34.189  -20.175 1.000 18.542 0 436  TRP A HA   1 c 
ATOM   6449 H HB2  . TRP A 1 409 ? 4.769   33.643  -22.542 1.000 16.878 0 436  TRP A HB2  1 c 
ATOM   6450 H HB3  . TRP A 1 409 ? 6.264   33.204  -22.380 1.000 16.869 0 436  TRP A HB3  1 c 
ATOM   6451 H HD1  . TRP A 1 409 ? 3.002   32.236  -20.828 1.000 16.852 0 436  TRP A HD1  1 c 
ATOM   6452 H HE1  . TRP A 1 409 ? 3.004   29.908  -20.239 1.000 16.705 0 436  TRP A HE1  1 c 
ATOM   6453 H HE3  . TRP A 1 409 ? 7.688   31.137  -21.912 1.000 16.892 0 436  TRP A HE3  1 c 
ATOM   6454 H HZ2  . TRP A 1 409 ? 4.769   27.798  -20.296 1.000 16.835 0 436  TRP A HZ2  1 c 
ATOM   6455 H HZ3  . TRP A 1 409 ? 8.383   28.948  -21.631 1.000 16.341 0 436  TRP A HZ3  1 c 
ATOM   6456 H HH2  . TRP A 1 409 ? 6.978   27.303  -20.845 1.000 16.321 0 436  TRP A HH2  1 c 
ATOM   6457 N N    . ALA A 1 410 ? 5.554   36.489  -22.314 1.000 20.783 0 437  ALA A N    1 ? 
ATOM   6458 C CA   . ALA A 1 410 ? 6.124   37.530  -23.162 1.000 19.708 0 437  ALA A CA   1 ? 
ATOM   6459 C C    . ALA A 1 410 ? 6.937   38.553  -22.377 1.000 18.519 0 437  ALA A C    1 ? 
ATOM   6460 O O    . ALA A 1 410 ? 7.964   39.011  -22.859 1.000 18.944 0 437  ALA A O    1 ? 
ATOM   6461 C CB   . ALA A 1 410 ? 5.032   38.233  -23.960 1.000 21.541 0 437  ALA A CB   1 ? 
ATOM   6462 H H    . ALA A 1 410 ? 4.646   36.416  -22.245 1.000 20.160 0 437  ALA A H    1 c 
ATOM   6463 H HA   . ALA A 1 410 ? 6.743   37.087  -23.806 1.000 19.992 0 437  ALA A HA   1 c 
ATOM   6464 H HB1  . ALA A 1 410 ? 4.458   37.571  -24.380 1.000 21.006 0 437  ALA A HB1  1 c 
ATOM   6465 H HB2  . ALA A 1 410 ? 4.500   38.791  -23.367 1.000 20.995 0 437  ALA A HB2  1 c 
ATOM   6466 H HB3  . ALA A 1 410 ? 5.438   38.788  -24.646 1.000 21.088 0 437  ALA A HB3  1 c 
ATOM   6467 N N    . THR A 1 411 ? 6.515   38.910  -21.177 1.000 20.142 0 438  THR A N    1 ? 
ATOM   6468 C CA   . THR A 1 411 ? 7.256   39.867  -20.363 1.000 20.241 0 438  THR A CA   1 ? 
ATOM   6469 C C    . THR A 1 411 ? 8.682   39.367  -20.070 1.000 19.538 0 438  THR A C    1 ? 
ATOM   6470 O O    . THR A 1 411 ? 9.672   40.086  -20.240 1.000 18.434 0 438  THR A O    1 ? 
ATOM   6471 C CB   . THR A 1 411 ? 6.439   40.151  -19.103 1.000 28.419 0 438  THR A CB   1 ? 
ATOM   6472 O OG1  . THR A 1 411 ? 5.266   40.771  -19.651 1.000 33.718 0 438  THR A OG1  1 ? 
ATOM   6473 C CG2  . THR A 1 411 ? 7.218   41.052  -18.167 1.000 30.398 0 438  THR A CG2  1 ? 
ATOM   6474 H H    . THR A 1 411 ? 5.740   38.556  -20.848 1.000 19.874 0 438  THR A H    1 c 
ATOM   6475 H HA   . THR A 1 411 ? 7.326   40.703  -20.874 1.000 21.452 0 438  THR A HA   1 c 
ATOM   6476 H HB   . THR A 1 411 ? 6.194   39.310  -18.649 1.000 27.909 0 438  THR A HB   1 c 
ATOM   6477 H HG1  . THR A 1 411 ? 5.495   41.488  -20.087 0.000 33.740 0 438  THR A HG1  1 c 
ATOM   6478 H HG21 . THR A 1 411 ? 6.626   41.388  -17.472 1.000 29.781 0 438  THR A HG21 1 c 
ATOM   6479 H HG22 . THR A 1 411 ? 7.586   41.801  -18.667 1.000 29.782 0 438  THR A HG22 1 c 
ATOM   6480 H HG23 . THR A 1 411 ? 7.943   40.550  -17.757 1.000 29.729 0 438  THR A HG23 1 c 
ATOM   6481 N N    . PHE A 1 412 ? 8.782   38.088  -19.754 1.000 17.488 0 439  PHE A N    1 ? 
ATOM   6482 C CA   . PHE A 1 412 ? 10.095  37.509  -19.473 1.000 16.568 0 439  PHE A CA   1 ? 
ATOM   6483 C C    . PHE A 1 412 ? 10.931  37.340  -20.734 1.000 16.598 0 439  PHE A C    1 ? 
ATOM   6484 O O    . PHE A 1 412 ? 12.153  37.508  -20.665 1.000 18.727 0 439  PHE A O    1 ? 
ATOM   6485 C CB   . PHE A 1 412 ? 9.983   36.214  -18.656 1.000 16.747 0 439  PHE A CB   1 ? 
ATOM   6486 C CG   . PHE A 1 412 ? 9.515   36.490  -17.247 1.000 17.778 0 439  PHE A CG   1 ? 
ATOM   6487 C CD1  . PHE A 1 412 ? 10.379  37.098  -16.347 1.000 21.608 0 439  PHE A CD1  1 ? 
ATOM   6488 C CD2  . PHE A 1 412 ? 8.240   36.160  -16.852 1.000 18.245 0 439  PHE A CD2  1 ? 
ATOM   6489 C CE1  . PHE A 1 412 ? 9.954   37.416  -15.062 1.000 24.559 0 439  PHE A CE1  1 ? 
ATOM   6490 C CE2  . PHE A 1 412 ? 7.850   36.400  -15.544 1.000 20.118 0 439  PHE A CE2  1 ? 
ATOM   6491 C CZ   . PHE A 1 412 ? 8.682   37.082  -14.691 1.000 22.219 0 439  PHE A CZ   1 ? 
ATOM   6492 H H    . PHE A 1 412 ? 8.037   37.561  -19.701 1.000 17.767 0 439  PHE A H    1 c 
ATOM   6493 H HA   . PHE A 1 412 ? 10.576  38.163  -18.900 1.000 16.839 0 439  PHE A HA   1 c 
ATOM   6494 H HB2  . PHE A 1 412 ? 9.345   35.612  -19.100 1.000 16.966 0 439  PHE A HB2  1 c 
ATOM   6495 H HB3  . PHE A 1 412 ? 10.863  35.777  -18.627 1.000 16.941 0 439  PHE A HB3  1 c 
ATOM   6496 H HD1  . PHE A 1 412 ? 11.239  37.362  -16.634 1.000 21.233 0 439  PHE A HD1  1 c 
ATOM   6497 H HD2  . PHE A 1 412 ? 7.659   35.718  -17.449 1.000 18.661 0 439  PHE A HD2  1 c 
ATOM   6498 H HE1  . PHE A 1 412 ? 10.539  37.836  -14.452 1.000 23.264 0 439  PHE A HE1  1 c 
ATOM   6499 H HE2  . PHE A 1 412 ? 6.969   36.194  -15.274 1.000 20.146 0 439  PHE A HE2  1 c 
ATOM   6500 H HZ   . PHE A 1 412 ? 8.403   37.243  -13.804 1.000 22.159 0 439  PHE A HZ   1 c 
ATOM   6501 N N    . LEU A 1 413 ? 10.321  36.952  -21.871 1.000 15.914 0 440  LEU A N    1 ? 
ATOM   6502 C CA   . LEU A 1 413 ? 11.071  36.895  -23.113 1.000 14.887 0 440  LEU A CA   1 ? 
ATOM   6503 C C    . LEU A 1 413 ? 11.684  38.253  -23.435 1.000 15.705 0 440  LEU A C    1 ? 
ATOM   6504 O O    . LEU A 1 413 ? 12.891  38.350  -23.690 1.000 16.444 0 440  LEU A O    1 ? 
ATOM   6505 C CB   . LEU A 1 413 ? 10.172  36.454  -24.273 1.000 15.116 0 440  LEU A CB   1 ? 
ATOM   6506 C CG   . LEU A 1 413 ? 10.822  36.573  -25.636 1.000 15.719 0 440  LEU A CG   1 ? 
ATOM   6507 C CD1  . LEU A 1 413 ? 12.048  35.680  -25.785 1.000 16.678 0 440  LEU A CD1  1 ? 
ATOM   6508 C CD2  . LEU A 1 413 ? 9.772   36.233  -26.715 1.000 18.346 0 440  LEU A CD2  1 ? 
ATOM   6509 H H    . LEU A 1 413 ? 9.437   36.720  -21.867 1.000 15.840 0 440  LEU A H    1 c 
ATOM   6510 H HA   . LEU A 1 413 ? 11.803  36.237  -23.002 1.000 15.301 0 440  LEU A HA   1 c 
ATOM   6511 H HB2  . LEU A 1 413 ? 9.915   35.515  -24.127 1.000 15.200 0 440  LEU A HB2  1 c 
ATOM   6512 H HB3  . LEU A 1 413 ? 9.358   37.008  -24.263 1.000 15.200 0 440  LEU A HB3  1 c 
ATOM   6513 H HG   . LEU A 1 413 ? 11.104  37.514  -25.771 1.000 16.229 0 440  LEU A HG   1 c 
ATOM   6514 H HD11 . LEU A 1 413 ? 12.738  35.966  -25.164 1.000 16.368 0 440  LEU A HD11 1 c 
ATOM   6515 H HD12 . LEU A 1 413 ? 12.387  35.742  -26.694 1.000 16.380 0 440  LEU A HD12 1 c 
ATOM   6516 H HD13 . LEU A 1 413 ? 11.804  34.759  -25.594 1.000 16.360 0 440  LEU A HD13 1 c 
ATOM   6517 H HD21 . LEU A 1 413 ? 9.026   36.853  -26.650 1.000 17.555 0 440  LEU A HD21 1 c 
ATOM   6518 H HD22 . LEU A 1 413 ? 9.450   35.326  -26.581 1.000 17.555 0 440  LEU A HD22 1 c 
ATOM   6519 H HD23 . LEU A 1 413 ? 10.176  36.305  -27.596 1.000 17.607 0 440  LEU A HD23 1 c 
ATOM   6520 N N    . VAL A 1 414 ? 10.893  39.329  -23.349 1.000 15.849 0 441  VAL A N    1 ? 
ATOM   6521 C CA   . VAL A 1 414 ? 11.437  40.653  -23.636 1.000 16.957 0 441  VAL A CA   1 ? 
ATOM   6522 C C    . VAL A 1 414 ? 12.599  41.025  -22.708 1.000 17.990 0 441  VAL A C    1 ? 
ATOM   6523 O O    . VAL A 1 414 ? 13.637  41.549  -23.148 1.000 18.545 0 441  VAL A O    1 ? 
ATOM   6524 C CB   . VAL A 1 414 ? 10.332  41.708  -23.567 1.000 18.443 0 441  VAL A CB   1 ? 
ATOM   6525 C CG1  . VAL A 1 414 ? 10.927  43.112  -23.552 1.000 23.250 0 441  VAL A CG1  1 ? 
ATOM   6526 C CG2  . VAL A 1 414 ? 9.378   41.521  -24.751 1.000 19.639 0 441  VAL A CG2  1 ? 
ATOM   6527 H H    . VAL A 1 414 ? 10.014  39.242  -23.113 1.000 16.121 0 441  VAL A H    1 c 
ATOM   6528 H HA   . VAL A 1 414 ? 11.779  40.639  -24.551 1.000 17.196 0 441  VAL A HA   1 c 
ATOM   6529 H HB   . VAL A 1 414 ? 9.832   41.565  -22.729 1.000 19.153 0 441  VAL A HB   1 c 
ATOM   6530 H HG11 . VAL A 1 414 ? 11.622  43.179  -24.229 1.000 21.689 0 441  VAL A HG11 1 c 
ATOM   6531 H HG12 . VAL A 1 414 ? 11.308  43.298  -22.677 1.000 21.687 0 441  VAL A HG12 1 c 
ATOM   6532 H HG13 . VAL A 1 414 ? 10.229  43.761  -23.743 1.000 21.703 0 441  VAL A HG13 1 c 
ATOM   6533 H HG21 . VAL A 1 414 ? 8.675   42.192  -24.710 1.000 19.266 0 441  VAL A HG21 1 c 
ATOM   6534 H HG22 . VAL A 1 414 ? 8.981   40.635  -24.713 1.000 19.232 0 441  VAL A HG22 1 c 
ATOM   6535 H HG23 . VAL A 1 414 ? 9.869   41.619  -25.583 1.000 19.255 0 441  VAL A HG23 1 c 
ATOM   6536 N N    . GLN A 1 415 ? 12.468  40.688  -21.429 1.000 17.448 0 442  GLN A N    1 ? 
ATOM   6537 C CA   . GLN A 1 415 ? 13.486  41.009  -20.447 1.000 17.658 0 442  GLN A CA   1 ? 
ATOM   6538 C C    . GLN A 1 415 ? 14.759  40.225  -20.771 1.000 16.809 0 442  GLN A C    1 ? 
ATOM   6539 O O    . GLN A 1 415 ? 15.888  40.769  -20.715 1.000 18.676 0 442  GLN A O    1 ? 
ATOM   6540 C CB   . GLN A 1 415 ? 12.948  40.709  -19.050 1.000 18.512 0 442  GLN A CB   1 ? 
ATOM   6541 C CG   . GLN A 1 415 ? 13.953  40.961  -17.946 1.000 21.492 0 442  GLN A CG   1 ? 
ATOM   6542 C CD   . GLN A 1 415 ? 13.452  40.472  -16.607 1.000 24.436 0 442  GLN A CD   1 ? 
ATOM   6543 O OE1  . GLN A 1 415 ? 13.217  39.285  -16.370 1.000 25.552 0 442  GLN A OE1  1 ? 
ATOM   6544 N NE2  . GLN A 1 415 ? 13.385  41.401  -15.665 1.000 30.226 0 442  GLN A NE2  1 ? 
ATOM   6545 H H    . GLN A 1 415 ? 11.716  40.247  -21.155 1.000 17.622 0 442  GLN A H    1 c 
ATOM   6546 H HA   . GLN A 1 415 ? 13.685  41.978  -20.510 1.000 17.696 0 442  GLN A HA   1 c 
ATOM   6547 H HB2  . GLN A 1 415 ? 12.155  41.264  -18.892 1.000 18.956 0 442  GLN A HB2  1 c 
ATOM   6548 H HB3  . GLN A 1 415 ? 12.666  39.771  -19.016 1.000 18.970 0 442  GLN A HB3  1 c 
ATOM   6549 H HG2  . GLN A 1 415 ? 14.793  40.501  -18.156 1.000 21.382 0 442  GLN A HG2  1 c 
ATOM   6550 H HG3  . GLN A 1 415 ? 14.143  41.922  -17.893 1.000 21.479 0 442  GLN A HG3  1 c 
ATOM   6551 H HE21 . GLN A 1 415 ? 13.682  42.223  -15.819 1.000 28.169 0 442  GLN A HE21 1 c 
ATOM   6552 H HE22 . GLN A 1 415 ? 13.040  41.199  -14.873 1.000 28.255 0 442  GLN A HE22 1 c 
ATOM   6553 N N    . SER A 1 416 ? 14.586  38.926  -21.046 1.000 15.920 0 443  SER A N    1 ? 
ATOM   6554 C CA   . SER A 1 416 ? 15.721  38.071  -21.346 1.000 15.562 0 443  SER A CA   1 ? 
ATOM   6555 C C    . SER A 1 416 ? 16.446  38.514  -22.627 1.000 17.164 0 443  SER A C    1 ? 
ATOM   6556 O O    . SER A 1 416 ? 17.664  38.576  -22.670 1.000 17.414 0 443  SER A O    1 ? 
ATOM   6557 C CB   . SER A 1 416 ? 15.326  36.603  -21.371 1.000 16.941 0 443  SER A CB   1 ? 
ATOM   6558 O OG   . SER A 1 416 ? 14.990  36.130  -20.066 1.000 16.291 0 443  SER A OG   1 ? 
ATOM   6559 H H    . SER A 1 416 ? 13.746  38.566  -21.041 1.000 16.071 0 443  SER A H    1 c 
ATOM   6560 H HA   . SER A 1 416 ? 16.365  38.182  -20.601 1.000 16.184 0 443  SER A HA   1 c 
ATOM   6561 H HB2  . SER A 1 416 ? 14.560  36.486  -21.965 1.000 16.467 0 443  SER A HB2  1 c 
ATOM   6562 H HB3  . SER A 1 416 ? 16.068  36.077  -21.725 1.000 16.470 0 443  SER A HB3  1 c 
ATOM   6563 H HG   . SER A 1 416 ? 14.779  35.312  -20.121 0.000 16.230 0 443  SER A HG   1 c 
ATOM   6564 N N    . LEU A 1 417 ? 15.715  38.809  -23.701 1.000 16.635 0 444  LEU A N    1 ? 
ATOM   6565 C CA   . LEU A 1 417 ? 16.351  39.324  -24.912 1.000 18.680 0 444  LEU A CA   1 ? 
ATOM   6566 C C    . LEU A 1 417 ? 17.180  40.576  -24.627 1.000 20.074 0 444  LEU A C    1 ? 
ATOM   6567 O O    . LEU A 1 417 ? 18.267  40.716  -25.199 1.000 19.262 0 444  LEU A O    1 ? 
ATOM   6568 C CB   . LEU A 1 417 ? 15.301  39.628  -25.969 1.000 19.278 0 444  LEU A CB   1 ? 
ATOM   6569 C CG   . LEU A 1 417 ? 14.436  38.477  -26.496 1.000 18.658 0 444  LEU A CG   1 ? 
ATOM   6570 C CD1  . LEU A 1 417 ? 13.309  39.088  -27.366 1.000 18.782 0 444  LEU A CD1  1 ? 
ATOM   6571 C CD2  . LEU A 1 417 ? 15.222  37.484  -27.309 1.000 18.436 0 444  LEU A CD2  1 ? 
ATOM   6572 H H    . LEU A 1 417 ? 14.809  38.693  -23.684 1.000 17.213 0 444  LEU A H    1 c 
ATOM   6573 H HA   . LEU A 1 417 ? 16.960  38.623  -25.258 1.000 18.609 0 444  LEU A HA   1 c 
ATOM   6574 H HB2  . LEU A 1 417 ? 14.700  40.318  -25.605 1.000 18.996 0 444  LEU A HB2  1 c 
ATOM   6575 H HB3  . LEU A 1 417 ? 15.758  40.039  -26.738 1.000 19.002 0 444  LEU A HB3  1 c 
ATOM   6576 H HG   . LEU A 1 417 ? 14.028  38.006  -25.728 1.000 18.724 0 444  LEU A HG   1 c 
ATOM   6577 H HD11 . LEU A 1 417 ? 12.761  39.678  -26.822 1.000 18.748 0 444  LEU A HD11 1 c 
ATOM   6578 H HD12 . LEU A 1 417 ? 12.755  38.375  -27.727 1.000 18.746 0 444  LEU A HD12 1 c 
ATOM   6579 H HD13 . LEU A 1 417 ? 13.701  39.594  -28.098 1.000 18.746 0 444  LEU A HD13 1 c 
ATOM   6580 H HD21 . LEU A 1 417 ? 15.919  37.091  -26.758 1.000 18.502 0 444  LEU A HD21 1 c 
ATOM   6581 H HD22 . LEU A 1 417 ? 15.627  37.935  -28.069 1.000 18.502 0 444  LEU A HD22 1 c 
ATOM   6582 H HD23 . LEU A 1 417 ? 14.628  36.784  -27.628 1.000 18.502 0 444  LEU A HD23 1 c 
ATOM   6583 N N    . GLY A 1 418 ? 16.635  41.483  -23.801 1.000 19.865 0 445  GLY A N    1 ? 
ATOM   6584 C CA   . GLY A 1 418 ? 17.263  42.764  -23.485 1.000 22.596 0 445  GLY A CA   1 ? 
ATOM   6585 C C    . GLY A 1 418 ? 18.575  42.611  -22.719 1.000 22.596 0 445  GLY A C    1 ? 
ATOM   6586 O O    . GLY A 1 418 ? 19.340  43.576  -22.625 1.000 24.511 0 445  GLY A O    1 ? 
ATOM   6587 H H    . GLY A 1 418 ? 15.827  41.296  -23.418 1.000 20.460 0 445  GLY A H    1 c 
ATOM   6588 H HA2  . GLY A 1 418 ? 17.433  43.250  -24.326 1.000 21.928 0 445  GLY A HA2  1 c 
ATOM   6589 H HA3  . GLY A 1 418 ? 16.635  43.302  -22.949 1.000 21.987 0 445  GLY A HA3  1 c 
ATOM   6590 N N    . ARG A 1 419 ? 18.817  41.443  -22.121 1.000 18.931 0 446  ARG A N    1 ? 
ATOM   6591 C CA   . ARG A 1 419 ? 20.053  41.225  -21.384 1.000 19.870 0 446  ARG A CA   1 ? 
ATOM   6592 C C    . ARG A 1 419 ? 21.251  41.161  -22.332 1.000 23.100 0 446  ARG A C    1 ? 
ATOM   6593 O O    . ARG A 1 419 ? 22.394  41.303  -21.891 1.000 25.922 0 446  ARG A O    1 ? 
ATOM   6594 C CB   . ARG A 1 419 ? 19.992  39.944  -20.541 1.000 19.485 0 446  ARG A CB   1 ? 
ATOM   6595 C CG   . ARG A 1 419 ? 18.964  40.064  -19.429 1.000 20.412 0 446  ARG A CG   1 ? 
ATOM   6596 C CD   . ARG A 1 419 ? 19.509  40.876  -18.253 1.000 21.343 0 446  ARG A CD   1 ? 
ATOM   6597 N NE   . ARG A 1 419 ? 18.511  40.813  -17.182 1.000 20.264 0 446  ARG A NE   1 ? 
ATOM   6598 C CZ   . ARG A 1 419 ? 18.318  41.747  -16.281 1.000 27.109 0 446  ARG A CZ   1 ? 
ATOM   6599 N NH1  . ARG A 1 419 ? 19.074  42.835  -16.304 1.000 30.908 0 446  ARG A NH1  1 ? 
ATOM   6600 N NH2  . ARG A 1 419 ? 17.428  41.537  -15.314 1.000 28.091 0 446  ARG A NH2  1 ? 
ATOM   6601 H H    . ARG A 1 419 ? 18.198  40.773  -22.155 1.000 19.965 0 446  ARG A H    1 c 
ATOM   6602 H HA   . ARG A 1 419 ? 20.184  41.992  -20.771 1.000 20.206 0 446  ARG A HA   1 c 
ATOM   6603 H HB2  . ARG A 1 419 ? 19.758  39.186  -21.117 1.000 19.773 0 446  ARG A HB2  1 c 
ATOM   6604 H HB3  . ARG A 1 419 ? 20.874  39.770  -20.149 1.000 19.809 0 446  ARG A HB3  1 c 
ATOM   6605 H HG2  . ARG A 1 419 ? 18.158  40.501  -19.774 1.000 20.380 0 446  ARG A HG2  1 c 
ATOM   6606 H HG3  . ARG A 1 419 ? 18.719  39.166  -19.115 1.000 20.408 0 446  ARG A HG3  1 c 
ATOM   6607 H HD2  . ARG A 1 419 ? 20.357  40.501  -17.938 1.000 20.892 0 446  ARG A HD2  1 c 
ATOM   6608 H HD3  . ARG A 1 419 ? 19.652  41.806  -18.520 1.000 20.997 0 446  ARG A HD3  1 c 
ATOM   6609 H HE   . ARG A 1 419 ? 18.009  40.103  -17.137 1.000 22.036 0 446  ARG A HE   1 c 
ATOM   6610 H HH11 . ARG A 1 419 ? 18.697  43.628  -16.445 1.000 29.671 0 446  ARG A HH11 1 c 
ATOM   6611 H HH12 . ARG A 1 419 ? 19.952  42.763  -16.176 1.000 29.626 0 446  ARG A HH12 1 c 
ATOM   6612 H HH21 . ARG A 1 419 ? 17.262  42.178  -14.727 1.000 27.778 0 446  ARG A HH21 1 c 
ATOM   6613 H HH22 . ARG A 1 419 ? 17.005  40.763  -15.257 1.000 27.665 0 446  ARG A HH22 1 c 
ATOM   6614 N N    . PHE A 1 420 ? 20.988  40.894  -23.632 1.000 19.439 0 447  PHE A N    1 ? 
ATOM   6615 C CA   . PHE A 1 420 ? 22.030  40.789  -24.634 1.000 20.164 0 447  PHE A CA   1 ? 
ATOM   6616 C C    . PHE A 1 420 ? 22.056  42.074  -25.457 1.000 21.964 0 447  PHE A C    1 ? 
ATOM   6617 O O    . PHE A 1 420 ? 21.024  42.531  -25.948 1.000 22.067 0 447  PHE A O    1 ? 
ATOM   6618 C CB   . PHE A 1 420 ? 21.800  39.620  -25.598 1.000 20.101 0 447  PHE A CB   1 ? 
ATOM   6619 C CG   . PHE A 1 420 ? 21.787  38.270  -24.926 1.000 19.104 0 447  PHE A CG   1 ? 
ATOM   6620 C CD1  . PHE A 1 420 ? 20.651  37.818  -24.231 1.000 19.461 0 447  PHE A CD1  1 ? 
ATOM   6621 C CD2  . PHE A 1 420 ? 22.884  37.433  -25.031 1.000 20.417 0 447  PHE A CD2  1 ? 
ATOM   6622 C CE1  . PHE A 1 420 ? 20.644  36.556  -23.678 1.000 17.875 0 447  PHE A CE1  1 ? 
ATOM   6623 C CE2  . PHE A 1 420 ? 22.886  36.191  -24.432 1.000 22.363 0 447  PHE A CE2  1 ? 
ATOM   6624 C CZ   . PHE A 1 420 ? 21.760  35.761  -23.752 1.000 19.520 0 447  PHE A CZ   1 ? 
ATOM   6625 H H    . PHE A 1 420 ? 20.124  40.755  -23.893 1.000 20.420 0 447  PHE A H    1 c 
ATOM   6626 H HA   . PHE A 1 420 ? 22.908  40.669  -24.183 1.000 20.383 0 447  PHE A HA   1 c 
ATOM   6627 H HB2  . PHE A 1 420 ? 20.941  39.757  -26.055 1.000 19.895 0 447  PHE A HB2  1 c 
ATOM   6628 H HB3  . PHE A 1 420 ? 22.510  39.632  -26.279 1.000 19.901 0 447  PHE A HB3  1 c 
ATOM   6629 H HD1  . PHE A 1 420 ? 19.883  38.364  -24.178 1.000 19.018 0 447  PHE A HD1  1 c 
ATOM   6630 H HD2  . PHE A 1 420 ? 23.653  37.732  -25.488 1.000 20.505 0 447  PHE A HD2  1 c 
ATOM   6631 H HE1  . PHE A 1 420 ? 19.889  36.262  -23.194 1.000 18.656 0 447  PHE A HE1  1 c 
ATOM   6632 H HE2  . PHE A 1 420 ? 23.644  35.633  -24.499 1.000 21.161 0 447  PHE A HE2  1 c 
ATOM   6633 H HZ   . PHE A 1 420 ? 21.752  34.906  -23.352 1.000 19.736 0 447  PHE A HZ   1 c 
ATOM   6634 N N    . GLU A 1 421 ? 23.228  42.715  -25.568 1.000 21.345 0 448  GLU A N    1 ? 
ATOM   6635 C CA   . GLU A 1 421 ? 23.315  43.912  -26.384 1.000 22.520 0 448  GLU A CA   1 ? 
ATOM   6636 C C    . GLU A 1 421 ? 23.014  43.600  -27.859 1.000 19.896 0 448  GLU A C    1 ? 
ATOM   6637 O O    . GLU A 1 421 ? 23.270  42.498  -28.328 1.000 19.143 0 448  GLU A O    1 ? 
ATOM   6638 C CB   . GLU A 1 421 ? 24.712  44.518  -26.251 1.000 27.497 0 448  GLU A CB   1 ? 
ATOM   6639 C CG   . GLU A 1 421 ? 24.907  45.244  -24.933 1.000 35.093 0 448  GLU A CG   1 ? 
ATOM   6640 C CD   . GLU A 1 421 ? 24.039  46.466  -24.678 1.000 51.449 0 448  GLU A CD   1 ? 
ATOM   6641 O OE1  . GLU A 1 421 ? 22.786  46.365  -24.527 1.000 63.793 0 448  GLU A OE1  1 ? 
ATOM   6642 O OE2  . GLU A 1 421 ? 24.654  47.555  -24.594 1.000 69.828 0 448  GLU A OE2  1 ? 
ATOM   6643 H H    . GLU A 1 421 ? 23.971  42.407  -25.133 1.000 21.806 0 448  GLU A H    1 c 
ATOM   6644 H HA   . GLU A 1 421 ? 22.644  44.560  -26.058 1.000 22.847 0 448  GLU A HA   1 c 
ATOM   6645 H HB2  . GLU A 1 421 ? 25.379  43.805  -26.332 1.000 27.731 0 448  GLU A HB2  1 c 
ATOM   6646 H HB3  . GLU A 1 421 ? 24.857  45.148  -26.988 1.000 27.729 0 448  GLU A HB3  1 c 
ATOM   6647 H HG2  . GLU A 1 421 ? 24.752  44.607  -24.204 1.000 36.295 0 448  GLU A HG2  1 c 
ATOM   6648 H HG3  . GLU A 1 421 ? 25.846  45.521  -24.869 1.000 36.425 0 448  GLU A HG3  1 c 
ATOM   6649 N N    . GLY A 1 422 ? 22.546  44.606  -28.613 1.000 21.340 0 449  GLY A N    1 ? 
ATOM   6650 C CA   . GLY A 1 422 ? 22.301  44.486  -30.041 1.000 20.843 0 449  GLY A CA   1 ? 
ATOM   6651 C C    . GLY A 1 422 ? 23.493  43.958  -30.827 1.000 20.856 0 449  GLY A C    1 ? 
ATOM   6652 O O    . GLY A 1 422 ? 23.307  43.130  -31.719 1.000 23.996 0 449  GLY A O    1 ? 
ATOM   6653 H H    . GLY A 1 422 ? 22.372  45.408  -28.211 1.000 20.901 0 449  GLY A H    1 c 
ATOM   6654 H HA2  . GLY A 1 422 ? 21.533  43.884  -30.179 1.000 21.001 0 449  GLY A HA2  1 c 
ATOM   6655 H HA3  . GLY A 1 422 ? 22.051  45.373  -30.393 1.000 20.971 0 449  GLY A HA3  1 c 
ATOM   6656 N N    . GLN A 1 423 ? 24.719  44.401  -30.486 1.000 19.632 0 450  GLN A N    1 ? 
ATOM   6657 C CA   . GLN A 1 423 ? 25.923  43.985  -31.183 1.000 23.001 0 450  GLN A CA   1 ? 
ATOM   6658 C C    . GLN A 1 423 ? 26.152  42.482  -31.009 1.000 22.460 0 450  GLN A C    1 ? 
ATOM   6659 O O    . GLN A 1 423 ? 26.847  41.878  -31.819 1.000 24.486 0 450  GLN A O    1 ? 
ATOM   6660 C CB   . GLN A 1 423 ? 27.144  44.796  -30.729 1.000 27.360 0 450  GLN A CB   1 ? 
ATOM   6661 C CG   . GLN A 1 423 ? 27.078  46.293  -31.036 1.000 41.284 0 450  GLN A CG   1 ? 
ATOM   6662 C CD   . GLN A 1 423 ? 25.874  47.035  -30.469 1.000 51.406 0 450  GLN A CD   1 ? 
ATOM   6663 O OE1  . GLN A 1 423 ? 25.504  46.910  -29.279 1.000 39.421 0 450  GLN A OE1  1 ? 
ATOM   6664 N NE2  . GLN A 1 423 ? 25.238  47.812  -31.346 1.000 56.181 0 450  GLN A NE2  1 ? 
ATOM   6665 H H    . GLN A 1 423 ? 24.800  44.965  -29.772 1.000 20.844 0 450  GLN A H    1 c 
ATOM   6666 H HA   . GLN A 1 423 ? 25.788  44.163  -32.149 1.000 22.923 0 450  GLN A HA   1 c 
ATOM   6667 H HB2  . GLN A 1 423 ? 27.250  44.679  -29.762 1.000 28.912 0 450  GLN A HB2  1 c 
ATOM   6668 H HB3  . GLN A 1 423 ? 27.940  44.422  -31.160 1.000 28.881 0 450  GLN A HB3  1 c 
ATOM   6669 H HG2  . GLN A 1 423 ? 27.888  46.722  -30.686 1.000 39.541 0 450  GLN A HG2  1 c 
ATOM   6670 H HG3  . GLN A 1 423 ? 27.084  46.414  -32.009 1.000 39.682 0 450  GLN A HG3  1 c 
ATOM   6671 H HE21 . GLN A 1 423 ? 25.605  47.999  -32.133 1.000 54.353 0 450  GLN A HE21 1 c 
ATOM   6672 H HE22 . GLN A 1 423 ? 24.443  48.148  -31.138 1.000 54.465 0 450  GLN A HE22 1 c 
ATOM   6673 N N    . VAL A 1 424 ? 25.613  41.886  -29.929 1.000 17.577 0 451  VAL A N    1 ? 
ATOM   6674 C CA   . VAL A 1 424 ? 25.737  40.461  -29.737 1.000 18.662 0 451  VAL A CA   1 ? 
ATOM   6675 C C    . VAL A 1 424 ? 24.617  39.736  -30.467 1.000 17.262 0 451  VAL A C    1 ? 
ATOM   6676 O O    . VAL A 1 424 ? 24.849  38.770  -31.206 1.000 18.249 0 451  VAL A O    1 ? 
ATOM   6677 C CB   . VAL A 1 424 ? 25.722  40.126  -28.229 1.000 20.037 0 451  VAL A CB   1 ? 
ATOM   6678 C CG1  . VAL A 1 424 ? 25.680  38.620  -28.013 1.000 20.044 0 451  VAL A CG1  1 ? 
ATOM   6679 C CG2  . VAL A 1 424 ? 26.925  40.756  -27.535 1.000 21.558 0 451  VAL A CG2  1 ? 
ATOM   6680 H H    . VAL A 1 424 ? 25.180  42.383  -29.298 1.000 18.950 0 451  VAL A H    1 c 
ATOM   6681 H HA   . VAL A 1 424 ? 26.592  40.169  -30.109 1.000 18.470 0 451  VAL A HA   1 c 
ATOM   6682 H HB   . VAL A 1 424 ? 24.902  40.517  -27.847 1.000 20.036 0 451  VAL A HB   1 c 
ATOM   6683 H HG11 . VAL A 1 424 ? 26.329  38.190  -28.595 1.000 20.038 0 451  VAL A HG11 1 c 
ATOM   6684 H HG12 . VAL A 1 424 ? 24.790  38.284  -28.217 1.000 20.026 0 451  VAL A HG12 1 c 
ATOM   6685 H HG13 . VAL A 1 424 ? 25.894  38.419  -27.086 1.000 20.038 0 451  VAL A HG13 1 c 
ATOM   6686 H HG21 . VAL A 1 424 ? 26.854  40.618  -26.576 1.000 21.105 0 451  VAL A HG21 1 c 
ATOM   6687 H HG22 . VAL A 1 424 ? 26.948  41.709  -27.722 1.000 21.079 0 451  VAL A HG22 1 c 
ATOM   6688 H HG23 . VAL A 1 424 ? 27.742  40.342  -27.861 1.000 21.096 0 451  VAL A HG23 1 c 
ATOM   6689 N N    . ARG A 1 425 ? 23.388  40.246  -30.314 1.000 16.644 0 452  ARG A N    1 ? 
ATOM   6690 C CA   . ARG A 1 425 ? 22.227  39.620  -30.935 1.000 17.040 0 452  ARG A CA   1 ? 
ATOM   6691 C C    . ARG A 1 425 ? 22.333  39.586  -32.467 1.000 18.601 0 452  ARG A C    1 ? 
ATOM   6692 O O    . ARG A 1 425 ? 21.942  38.613  -33.125 1.000 17.627 0 452  ARG A O    1 ? 
ATOM   6693 C CB   . ARG A 1 425 ? 20.952  40.331  -30.516 1.000 19.012 0 452  ARG A CB   1 ? 
ATOM   6694 C CG   . ARG A 1 425 ? 20.741  40.203  -29.015 1.000 18.845 0 452  ARG A CG   1 ? 
ATOM   6695 C CD   . ARG A 1 425 ? 19.380  40.717  -28.578 1.000 22.159 0 452  ARG A CD   1 ? 
ATOM   6696 N NE   . ARG A 1 425 ? 19.394  42.148  -28.302 1.000 22.906 0 452  ARG A NE   1 ? 
ATOM   6697 C CZ   . ARG A 1 425 ? 18.993  43.099  -29.124 1.000 26.049 0 452  ARG A CZ   1 ? 
ATOM   6698 N NH1  . ARG A 1 425 ? 18.427  42.819  -30.284 1.000 25.934 0 452  ARG A NH1  1 ? 
ATOM   6699 N NH2  . ARG A 1 425 ? 19.105  44.354  -28.735 1.000 27.375 0 452  ARG A NH2  1 ? 
ATOM   6700 H H    . ARG A 1 425 ? 23.270  41.004  -29.817 1.000 16.939 0 452  ARG A H    1 c 
ATOM   6701 H HA   . ARG A 1 425 ? 22.176  38.685  -30.610 1.000 17.599 0 452  ARG A HA   1 c 
ATOM   6702 H HB2  . ARG A 1 425 ? 21.011  41.280  -30.757 1.000 18.511 0 452  ARG A HB2  1 c 
ATOM   6703 H HB3  . ARG A 1 425 ? 20.187  39.939  -30.988 1.000 18.527 0 452  ARG A HB3  1 c 
ATOM   6704 H HG2  . ARG A 1 425 ? 20.824  39.260  -28.756 1.000 19.563 0 452  ARG A HG2  1 c 
ATOM   6705 H HG3  . ARG A 1 425 ? 21.437  40.708  -28.543 1.000 19.552 0 452  ARG A HG3  1 c 
ATOM   6706 H HD2  . ARG A 1 425 ? 18.719  40.524  -29.272 1.000 21.596 0 452  ARG A HD2  1 c 
ATOM   6707 H HD3  . ARG A 1 425 ? 19.108  40.238  -27.768 1.000 21.543 0 452  ARG A HD3  1 c 
ATOM   6708 H HE   . ARG A 1 425 ? 19.694  42.397  -27.523 1.000 23.486 0 452  ARG A HE   1 c 
ATOM   6709 H HH11 . ARG A 1 425 ? 17.677  43.233  -30.515 1.000 25.943 0 452  ARG A HH11 1 c 
ATOM   6710 H HH12 . ARG A 1 425 ? 18.801  42.227  -30.829 1.000 25.858 0 452  ARG A HH12 1 c 
ATOM   6711 H HH21 . ARG A 1 425 ? 18.888  45.005  -29.292 1.000 26.936 0 452  ARG A HH21 1 c 
ATOM   6712 H HH22 . ARG A 1 425 ? 19.396  44.545  -27.922 1.000 26.890 0 452  ARG A HH22 1 c 
ATOM   6713 N N    . GLN A 1 426 ? 22.906  40.652  -33.033 1.000 18.223 0 453  GLN A N    1 ? 
ATOM   6714 C CA   . GLN A 1 426 ? 23.010  40.780  -34.486 1.000 18.240 0 453  GLN A CA   1 ? 
ATOM   6715 C C    . GLN A 1 426 ? 23.953  39.749  -35.101 1.000 20.406 0 453  GLN A C    1 ? 
ATOM   6716 O O    . GLN A 1 426 ? 23.883  39.533  -36.308 1.000 25.009 0 453  GLN A O    1 ? 
ATOM   6717 C CB   . GLN A 1 426 ? 23.448  42.209  -34.802 1.000 20.521 0 453  GLN A CB   1 ? 
ATOM   6718 C CG   . GLN A 1 426 ? 22.251  43.128  -34.603 1.000 28.199 0 453  GLN A CG   1 ? 
ATOM   6719 C CD   . GLN A 1 426 ? 22.450  44.596  -34.897 1.000 40.280 0 453  GLN A CD   1 ? 
ATOM   6720 O OE1  . GLN A 1 426 ? 21.475  45.354  -34.865 1.000 37.937 0 453  GLN A OE1  1 ? 
ATOM   6721 N NE2  . GLN A 1 426 ? 23.665  44.997  -35.241 1.000 41.416 0 453  GLN A NE2  1 ? 
ATOM   6722 H H    . GLN A 1 426 ? 23.236  41.321  -32.506 1.000 18.329 0 453  GLN A H    1 c 
ATOM   6723 H HA   . GLN A 1 426 ? 22.107  40.638  -34.871 1.000 19.109 0 453  GLN A HA   1 c 
ATOM   6724 H HB2  . GLN A 1 426 ? 24.178  42.476  -34.205 1.000 21.582 0 453  GLN A HB2  1 c 
ATOM   6725 H HB3  . GLN A 1 426 ? 23.763  42.268  -35.728 1.000 21.501 0 453  GLN A HB3  1 c 
ATOM   6726 H HG2  . GLN A 1 426 ? 21.524  42.813  -35.180 1.000 28.490 0 453  GLN A HG2  1 c 
ATOM   6727 H HG3  . GLN A 1 426 ? 21.940  43.046  -33.679 1.000 28.410 0 453  GLN A HG3  1 c 
ATOM   6728 H HE21 . GLN A 1 426 ? 24.387  44.550  -34.964 1.000 40.475 0 453  GLN A HE21 1 c 
ATOM   6729 H HE22 . GLN A 1 426 ? 23.755  45.728  -35.749 1.000 40.902 0 453  GLN A HE22 1 c 
ATOM   6730 N N    . LYS A 1 427 ? 24.805  39.096  -34.298 1.000 17.709 0 454  LYS A N    1 ? 
ATOM   6731 C CA   . LYS A 1 427 ? 25.738  38.096  -34.787 1.000 18.862 0 454  LYS A CA   1 ? 
ATOM   6732 C C    . LYS A 1 427 ? 25.094  36.736  -35.043 1.000 21.172 0 454  LYS A C    1 ? 
ATOM   6733 O O    . LYS A 1 427 ? 25.719  35.876  -35.669 1.000 24.391 0 454  LYS A O    1 ? 
ATOM   6734 C CB   . LYS A 1 427 ? 26.950  37.939  -33.881 1.000 20.670 0 454  LYS A CB   1 ? 
ATOM   6735 C CG   . LYS A 1 427 ? 27.763  39.231  -33.745 1.000 21.604 0 454  LYS A CG   1 ? 
ATOM   6736 C CD   . LYS A 1 427 ? 29.161  38.935  -33.241 1.000 25.262 0 454  LYS A CD   1 ? 
ATOM   6737 C CE   . LYS A 1 427 ? 30.062  40.114  -33.237 1.000 25.587 0 454  LYS A CE   1 ? 
ATOM   6738 N NZ   . LYS A 1 427 ? 29.695  40.922  -32.087 1.000 33.156 0 454  LYS A NZ   1 ? 
ATOM   6739 H H    . LYS A 1 427 ? 24.815  39.296  -33.407 1.000 18.588 0 454  LYS A H    1 c 
ATOM   6740 H HA   . LYS A 1 427 ? 26.086  38.420  -35.656 1.000 19.412 0 454  LYS A HA   1 c 
ATOM   6741 H HB2  . LYS A 1 427 ? 26.651  37.659  -32.989 1.000 20.467 0 454  LYS A HB2  1 c 
ATOM   6742 H HB3  . LYS A 1 427 ? 27.531  37.235  -34.240 1.000 20.520 0 454  LYS A HB3  1 c 
ATOM   6743 H HG2  . LYS A 1 427 ? 27.815  39.673  -34.620 1.000 22.161 0 454  LYS A HG2  1 c 
ATOM   6744 H HG3  . LYS A 1 427 ? 27.307  39.830  -33.117 1.000 22.227 0 454  LYS A HG3  1 c 
ATOM   6745 H HD2  . LYS A 1 427 ? 29.100  38.576  -32.329 1.000 24.532 0 454  LYS A HD2  1 c 
ATOM   6746 H HD3  . LYS A 1 427 ? 29.558  38.237  -33.806 1.000 24.438 0 454  LYS A HD3  1 c 
ATOM   6747 H HE2  . LYS A 1 427 ? 30.992  39.834  -33.160 1.000 27.135 0 454  LYS A HE2  1 c 
ATOM   6748 H HE3  . LYS A 1 427 ? 29.950  40.633  -34.054 1.000 27.135 0 454  LYS A HE3  1 c 
ATOM   6749 H HZ1  . LYS A 1 427 ? 29.771  40.438  -31.325 1.000 30.484 0 454  LYS A HZ1  1 c 
ATOM   6750 H HZ2  . LYS A 1 427 ? 28.844  41.221  -32.169 1.000 30.429 0 454  LYS A HZ2  1 c 
ATOM   6751 H HZ3  . LYS A 1 427 ? 30.250  41.636  -32.035 1.000 30.550 0 454  LYS A HZ3  1 c 
ATOM   6752 N N    . VAL A 1 428 ? 23.853  36.528  -34.595 1.000 20.706 0 455  VAL A N    1 ? 
ATOM   6753 C CA   . VAL A 1 428 ? 23.277  35.224  -34.842 1.000 21.842 0 455  VAL A CA   1 ? 
ATOM   6754 C C    . VAL A 1 428 ? 22.670  35.236  -36.238 1.000 24.988 0 455  VAL A C    1 ? 
ATOM   6755 O O    . VAL A 1 428 ? 21.868  36.119  -36.565 1.000 25.169 0 455  VAL A O    1 ? 
ATOM   6756 C CB   . VAL A 1 428 ? 22.248  34.894  -33.738 1.000 23.879 0 455  VAL A CB   1 ? 
ATOM   6757 C CG1  . VAL A 1 428 ? 21.526  33.581  -34.045 1.000 26.278 0 455  VAL A CG1  1 ? 
ATOM   6758 C CG2  . VAL A 1 428 ? 22.908  34.789  -32.381 1.000 26.251 0 455  VAL A CG2  1 ? 
ATOM   6759 H H    . VAL A 1 428 ? 23.381  37.167  -34.144 1.000 21.052 0 455  VAL A H    1 c 
ATOM   6760 H HA   . VAL A 1 428 ? 23.988  34.555  -34.812 1.000 22.582 0 455  VAL A HA   1 c 
ATOM   6761 H HB   . VAL A 1 428 ? 21.586  35.625  -33.716 1.000 24.334 0 455  VAL A HB   1 c 
ATOM   6762 H HG11 . VAL A 1 428 ? 22.180  32.887  -34.236 1.000 25.549 0 455  VAL A HG11 1 c 
ATOM   6763 H HG12 . VAL A 1 428 ? 20.946  33.699  -34.816 1.000 25.547 0 455  VAL A HG12 1 c 
ATOM   6764 H HG13 . VAL A 1 428 ? 20.990  33.317  -33.278 1.000 25.552 0 455  VAL A HG13 1 c 
ATOM   6765 H HG21 . VAL A 1 428 ? 22.268  34.452  -31.732 1.000 25.462 0 455  VAL A HG21 1 c 
ATOM   6766 H HG22 . VAL A 1 428 ? 23.220  35.666  -32.102 1.000 25.502 0 455  VAL A HG22 1 c 
ATOM   6767 H HG23 . VAL A 1 428 ? 23.663  34.179  -32.434 1.000 25.607 0 455  VAL A HG23 1 c 
ATOM   6768 N N    . ARG A 1 429 ? 22.969  34.204  -37.043 1.000 28.052 0 456  ARG A N    1 ? 
ATOM   6769 C CA   . ARG A 1 429 ? 22.370  34.139  -38.370 1.000 28.672 0 456  ARG A CA   1 ? 
ATOM   6770 C C    . ARG A 1 429 ? 21.189  33.164  -38.343 1.000 23.824 0 456  ARG A C    1 ? 
ATOM   6771 O O    . ARG A 1 429 ? 21.378  32.020  -37.955 1.000 26.306 0 456  ARG A O    1 ? 
ATOM   6772 C CB   . ARG A 1 429 ? 23.368  33.710  -39.454 1.000 33.025 0 456  ARG A CB   1 ? 
ATOM   6773 H H    . ARG A 1 429 ? 23.540  33.544  -36.770 1.000 27.333 0 456  ARG A H    1 c 
ATOM   6774 H HA   . ARG A 1 429 ? 22.032  35.040  -38.606 1.000 28.250 0 456  ARG A HA   1 c 
ATOM   6775 H HB2  . ARG A 1 429 ? 23.813  32.885  -39.162 1.000 31.781 0 456  ARG A HB2  1 c 
ATOM   6776 H HB3  . ARG A 1 429 ? 22.894  33.645  -40.310 0.000 32.930 0 456  ARG A HB3  1 c 
ATOM   6777 N N    . ILE A 1 430 ? 20.001  33.666  -38.670 1.000 25.622 0 457  ILE A N    1 ? 
ATOM   6778 C CA   . ILE A 1 430 ? 18.802  32.847  -38.641 1.000 29.450 0 457  ILE A CA   1 ? 
ATOM   6779 C C    . ILE A 1 430 ? 18.522  32.479  -40.093 1.000 32.935 0 457  ILE A C    1 ? 
ATOM   6780 O O    . ILE A 1 430 ? 18.228  33.370  -40.898 1.000 37.506 0 457  ILE A O    1 ? 
ATOM   6781 C CB   . ILE A 1 430 ? 17.636  33.585  -37.965 1.000 30.110 0 457  ILE A CB   1 ? 
ATOM   6782 C CG1  . ILE A 1 430 ? 18.045  33.947  -36.513 1.000 29.928 0 457  ILE A CG1  1 ? 
ATOM   6783 C CG2  . ILE A 1 430 ? 16.365  32.740  -38.009 1.000 33.851 0 457  ILE A CG2  1 ? 
ATOM   6784 C CD1  . ILE A 1 430 ? 17.127  34.902  -35.804 1.000 29.936 0 457  ILE A CD1  1 ? 
ATOM   6785 H H    . ILE A 1 430 ? 19.931  34.543  -38.919 1.000 26.023 0 457  ILE A H    1 c 
ATOM   6786 H HA   . ILE A 1 430 ? 18.988  32.035  -38.136 1.000 29.363 0 457  ILE A HA   1 c 
ATOM   6787 H HB   . ILE A 1 430 ? 17.474  34.416  -38.455 1.000 30.616 0 457  ILE A HB   1 c 
ATOM   6788 H HG12 . ILE A 1 430 ? 18.095  33.120  -35.990 1.000 29.964 0 457  ILE A HG12 1 c 
ATOM   6789 H HG13 . ILE A 1 430 ? 18.942  34.339  -36.530 1.000 29.939 0 457  ILE A HG13 1 c 
ATOM   6790 H HG21 . ILE A 1 430 ? 15.659  33.185  -37.511 1.000 32.670 0 457  ILE A HG21 1 c 
ATOM   6791 H HG22 . ILE A 1 430 ? 16.539  31.870  -37.611 1.000 32.697 0 457  ILE A HG22 1 c 
ATOM   6792 H HG23 . ILE A 1 430 ? 16.082  32.622  -38.931 1.000 32.699 0 457  ILE A HG23 1 c 
ATOM   6793 H HD11 . ILE A 1 430 ? 17.048  35.725  -36.323 1.000 29.894 0 457  ILE A HD11 1 c 
ATOM   6794 H HD12 . ILE A 1 430 ? 17.490  35.109  -34.922 1.000 29.894 0 457  ILE A HD12 1 c 
ATOM   6795 H HD13 . ILE A 1 430 ? 16.245  34.498  -35.703 1.000 29.769 0 457  ILE A HD13 1 c 
ATOM   6796 N N    . VAL A 1 431 ? 18.657  31.189  -40.387 1.000 32.593 0 458  VAL A N    1 ? 
ATOM   6797 C CA   . VAL A 1 431 ? 18.561  30.714  -41.760 1.000 40.132 0 458  VAL A CA   1 ? 
ATOM   6798 C C    . VAL A 1 431 ? 17.269  29.919  -41.931 1.000 37.339 0 458  VAL A C    1 ? 
ATOM   6799 O O    . VAL A 1 431 ? 16.784  29.267  -41.003 1.000 32.129 0 458  VAL A O    1 ? 
ATOM   6800 C CB   . VAL A 1 431 ? 19.807  29.919  -42.181 1.000 42.526 0 458  VAL A CB   1 ? 
ATOM   6801 C CG1  . VAL A 1 431 ? 21.095  30.705  -41.913 1.000 48.663 0 458  VAL A CG1  1 ? 
ATOM   6802 C CG2  . VAL A 1 431 ? 19.864  28.542  -41.535 1.000 47.148 0 458  VAL A CG2  1 ? 
ATOM   6803 H H    . VAL A 1 431 ? 18.808  30.583  -39.719 1.000 34.238 0 458  VAL A H    1 c 
ATOM   6804 H HA   . VAL A 1 431 ? 18.506  31.498  -42.340 1.000 38.440 0 458  VAL A HA   1 c 
ATOM   6805 H HB   . VAL A 1 431 ? 19.744  29.783  -43.156 1.000 43.980 0 458  VAL A HB   1 c 
ATOM   6806 H HG11 . VAL A 1 431 ? 21.207  30.830  -40.956 1.000 46.681 0 458  VAL A HG11 1 c 
ATOM   6807 H HG12 . VAL A 1 431 ? 21.042  31.573  -42.348 1.000 46.754 0 458  VAL A HG12 1 c 
ATOM   6808 H HG13 . VAL A 1 431 ? 21.855  30.213  -42.266 1.000 46.754 0 458  VAL A HG13 1 c 
ATOM   6809 H HG21 . VAL A 1 431 ? 20.735  28.143  -41.699 1.000 45.700 0 458  VAL A HG21 1 c 
ATOM   6810 H HG22 . VAL A 1 431 ? 19.173  27.974  -41.916 1.000 45.663 0 458  VAL A HG22 1 c 
ATOM   6811 H HG23 . VAL A 1 431 ? 19.723  28.626  -40.577 1.000 45.628 0 458  VAL A HG23 1 c 
ATOM   6812 N N    . SER A 1 432 ? 16.679  30.109  -43.117 1.000 41.884 0 459  SER A N    1 ? 
ATOM   6813 C CA   . SER A 1 432 ? 15.438  29.483  -43.533 1.000 46.511 0 459  SER A CA   1 ? 
ATOM   6814 C C    . SER A 1 432 ? 15.668  28.029  -43.912 1.000 53.343 0 459  SER A C    1 ? 
ATOM   6815 O O    . SER A 1 432 ? 16.741  27.685  -44.395 1.000 59.646 0 459  SER A O    1 ? 
ATOM   6816 C CB   . SER A 1 432 ? 14.870  30.205  -44.721 1.000 48.586 0 459  SER A CB   1 ? 
ATOM   6817 O OG   . SER A 1 432 ? 14.847  31.598  -44.467 1.000 56.849 0 459  SER A OG   1 ? 
ATOM   6818 H H    . SER A 1 432 ? 17.088  30.670  -43.711 1.000 41.743 0 459  SER A H    1 c 
ATOM   6819 H HA   . SER A 1 432 ? 14.790  29.524  -42.785 1.000 47.097 0 459  SER A HA   1 c 
ATOM   6820 H HB2  . SER A 1 432 ? 15.419  30.024  -45.508 1.000 49.960 0 459  SER A HB2  1 c 
ATOM   6821 H HB3  . SER A 1 432 ? 13.966  29.887  -44.894 1.000 49.943 0 459  SER A HB3  1 c 
ATOM   6822 H HG   . SER A 1 432 ? 14.494  31.968  -45.145 0.000 56.930 0 459  SER A HG   1 c 
ATOM   6823 N N    . VAL A 1 433 ? 14.623  27.214  -43.729 1.000 63.322 0 460  VAL A N    1 ? 
ATOM   6824 C CA   . VAL A 1 433 ? 14.511  25.950  -44.442 1.000 74.955 0 460  VAL A CA   1 ? 
ATOM   6825 C C    . VAL A 1 433 ? 13.369  26.099  -45.453 1.000 66.654 0 460  VAL A C    1 ? 
ATOM   6826 O O    . VAL A 1 433 ? 12.248  26.437  -45.079 1.000 57.722 0 460  VAL A O    1 ? 
ATOM   6827 C CB   . VAL A 1 433 ? 14.355  24.721  -43.518 1.000 74.746 0 460  VAL A CB   1 ? 
ATOM   6828 C CG1  . VAL A 1 433 ? 13.603  23.564  -44.174 1.000 74.367 0 460  VAL A CG1  1 ? 
ATOM   6829 C CG2  . VAL A 1 433 ? 15.715  24.248  -43.009 1.000 76.174 0 460  VAL A CG2  1 ? 
ATOM   6830 H HA   . VAL A 1 433 ? 15.336  25.828  -44.940 1.000 70.813 0 460  VAL A HA   1 c 
ATOM   6831 H HB   . VAL A 1 433 ? 13.829  25.012  -42.736 1.000 74.907 0 460  VAL A HB   1 c 
ATOM   6832 H HG11 . VAL A 1 433 ? 13.991  23.374  -45.044 1.000 74.425 0 460  VAL A HG11 1 c 
ATOM   6833 H HG12 . VAL A 1 433 ? 12.666  23.801  -44.280 1.000 74.425 0 460  VAL A HG12 1 c 
ATOM   6834 H HG13 . VAL A 1 433 ? 13.672  22.773  -43.612 1.000 74.467 0 460  VAL A HG13 1 c 
ATOM   6835 H HG21 . VAL A 1 433 ? 15.588  23.568  -42.325 1.000 75.608 0 460  VAL A HG21 1 c 
ATOM   6836 H HG22 . VAL A 1 433 ? 16.199  25.001  -42.630 1.000 75.154 0 460  VAL A HG22 1 c 
ATOM   6837 H HG23 . VAL A 1 433 ? 16.225  23.873  -43.746 1.000 75.608 0 460  VAL A HG23 1 c 
ATOM   6838 N N    . PRO A 1 434 ? 13.613  25.861  -46.763 1.000 67.905 0 461  PRO A N    1 ? 
ATOM   6839 C CA   . PRO A 1 434 ? 14.883  25.306  -47.248 1.000 76.173 0 461  PRO A CA   1 ? 
ATOM   6840 C C    . PRO A 1 434 ? 16.020  26.325  -47.325 1.000 70.498 0 461  PRO A C    1 ? 
ATOM   6841 O O    . PRO A 1 434 ? 15.804  27.518  -47.124 1.000 63.729 0 461  PRO A O    1 ? 
ATOM   6842 C CB   . PRO A 1 434 ? 14.482  24.768  -48.639 1.000 77.856 0 461  PRO A CB   1 ? 
ATOM   6843 C CG   . PRO A 1 434 ? 13.427  25.744  -49.119 1.000 74.715 0 461  PRO A CG   1 ? 
ATOM   6844 C CD   . PRO A 1 434 ? 12.664  26.133  -47.854 1.000 73.578 0 461  PRO A CD   1 ? 
ATOM   6845 H HA   . PRO A 1 434 ? 15.150  24.548  -46.671 1.000 73.739 0 461  PRO A HA   1 c 
ATOM   6846 H HB2  . PRO A 1 434 ? 15.256  24.757  -49.250 1.000 76.726 0 461  PRO A HB2  1 c 
ATOM   6847 H HB3  . PRO A 1 434 ? 14.113  23.856  -48.571 1.000 76.755 0 461  PRO A HB3  1 c 
ATOM   6848 H HG2  . PRO A 1 434 ? 13.841  26.531  -49.532 1.000 75.156 0 461  PRO A HG2  1 c 
ATOM   6849 H HG3  . PRO A 1 434 ? 12.830  25.321  -49.771 1.000 75.156 0 461  PRO A HG3  1 c 
ATOM   6850 H HD2  . PRO A 1 434 ? 12.413  27.083  -47.874 1.000 72.462 0 461  PRO A HD2  1 c 
ATOM   6851 H HD3  . PRO A 1 434 ? 11.850  25.590  -47.756 1.000 72.462 0 461  PRO A HD3  1 c 
ATOM   6852 N N    . PRO A 1 445 ? 27.442  31.862  -35.162 1.000 50.501 0 549  PRO A N    1 ? 
ATOM   6853 C CA   . PRO A 1 445 ? 26.338  30.989  -34.801 1.000 47.429 0 549  PRO A CA   1 ? 
ATOM   6854 C C    . PRO A 1 445 ? 25.271  31.029  -35.880 1.000 40.766 0 549  PRO A C    1 ? 
ATOM   6855 O O    . PRO A 1 445 ? 24.977  32.071  -36.456 1.000 38.609 0 549  PRO A O    1 ? 
ATOM   6856 C CB   . PRO A 1 445 ? 25.783  31.516  -33.477 1.000 45.090 0 549  PRO A CB   1 ? 
ATOM   6857 C CG   . PRO A 1 445 ? 26.468  32.823  -33.320 1.000 47.088 0 549  PRO A CG   1 ? 
ATOM   6858 C CD   . PRO A 1 445 ? 27.104  33.168  -34.649 1.000 46.410 0 549  PRO A CD   1 ? 
ATOM   6859 H H    . PRO A 1 445 ? 28.143  31.620  -35.597 1.000 48.855 0 549  PRO A H    1 c 
ATOM   6860 H HA   . PRO A 1 445 ? 26.673  30.065  -34.683 1.000 46.165 0 549  PRO A HA   1 c 
ATOM   6861 H HB2  . PRO A 1 445 ? 24.804  31.631  -33.521 1.000 46.042 0 549  PRO A HB2  1 c 
ATOM   6862 H HB3  . PRO A 1 445 ? 26.003  30.915  -32.735 1.000 46.158 0 549  PRO A HB3  1 c 
ATOM   6863 H HG2  . PRO A 1 445 ? 25.822  33.513  -33.066 1.000 45.697 0 549  PRO A HG2  1 c 
ATOM   6864 H HG3  . PRO A 1 445 ? 27.153  32.765  -32.622 1.000 46.007 0 549  PRO A HG3  1 c 
ATOM   6865 H HD2  . PRO A 1 445 ? 26.471  33.630  -35.238 1.000 47.196 0 549  PRO A HD2  1 c 
ATOM   6866 H HD3  . PRO A 1 445 ? 27.906  33.723  -34.527 1.000 47.439 0 549  PRO A HD3  1 c 
ATOM   6867 N N    . VAL A 1 446 ? 24.653  29.873  -36.099 1.000 37.670 0 550  VAL A N    1 ? 
ATOM   6868 C CA   . VAL A 1 446 ? 23.640  29.772  -37.122 1.000 38.588 0 550  VAL A CA   1 ? 
ATOM   6869 C C    . VAL A 1 446 ? 22.496  28.951  -36.536 1.000 36.593 0 550  VAL A C    1 ? 
ATOM   6870 O O    . VAL A 1 446 ? 22.715  27.936  -35.863 1.000 35.199 0 550  VAL A O    1 ? 
ATOM   6871 C CB   . VAL A 1 446 ? 24.216  29.135  -38.400 1.000 44.131 0 550  VAL A CB   1 ? 
ATOM   6872 C CG1  . VAL A 1 446 ? 24.193  27.619  -38.335 1.000 51.341 0 550  VAL A CG1  1 ? 
ATOM   6873 C CG2  . VAL A 1 446 ? 23.485  29.619  -39.643 1.000 42.450 0 550  VAL A CG2  1 ? 
ATOM   6874 H H    . VAL A 1 446 ? 24.866  29.135  -35.604 1.000 38.696 0 550  VAL A H    1 c 
ATOM   6875 H HA   . VAL A 1 446 ? 23.314  30.665  -37.333 1.000 38.805 0 550  VAL A HA   1 c 
ATOM   6876 H HB   . VAL A 1 446 ? 25.157  29.421  -38.470 1.000 43.927 0 550  VAL A HB   1 c 
ATOM   6877 H HG11 . VAL A 1 446 ? 23.276  27.302  -38.398 1.000 48.882 0 550  VAL A HG11 1 c 
ATOM   6878 H HG12 . VAL A 1 446 ? 24.583  27.322  -37.496 1.000 48.885 0 550  VAL A HG12 1 c 
ATOM   6879 H HG13 . VAL A 1 446 ? 24.709  27.257  -39.075 1.000 49.010 0 550  VAL A HG13 1 c 
ATOM   6880 H HG21 . VAL A 1 446 ? 23.863  29.192  -40.430 1.000 42.917 0 550  VAL A HG21 1 c 
ATOM   6881 H HG22 . VAL A 1 446 ? 23.580  30.583  -39.722 1.000 42.849 0 550  VAL A HG22 1 c 
ATOM   6882 H HG23 . VAL A 1 446 ? 22.542  29.393  -39.575 1.000 42.917 0 550  VAL A HG23 1 c 
ATOM   6883 N N    . LEU A 1 447 ? 21.277  29.412  -36.794 1.000 30.919 0 551  LEU A N    1 ? 
ATOM   6884 C CA   . LEU A 1 447 ? 20.123  28.767  -36.191 1.000 30.363 0 551  LEU A CA   1 ? 
ATOM   6885 C C    . LEU A 1 447 ? 19.051  28.657  -37.261 1.000 24.556 0 551  LEU A C    1 ? 
ATOM   6886 O O    . LEU A 1 447 ? 18.898  29.609  -38.016 1.000 27.901 0 551  LEU A O    1 ? 
ATOM   6887 C CB   . LEU A 1 447 ? 19.746  29.706  -35.042 1.000 35.681 0 551  LEU A CB   1 ? 
ATOM   6888 C CG   . LEU A 1 447 ? 18.461  29.398  -34.294 1.000 38.486 0 551  LEU A CG   1 ? 
ATOM   6889 C CD1  . LEU A 1 447 ? 18.566  28.018  -33.719 1.000 41.420 0 551  LEU A CD1  1 ? 
ATOM   6890 C CD2  . LEU A 1 447 ? 18.261  30.467  -33.224 1.000 36.762 0 551  LEU A CD2  1 ? 
ATOM   6891 H H    . LEU A 1 447 ? 21.156  30.129  -37.348 1.000 32.098 0 551  LEU A H    1 c 
ATOM   6892 H HA   . LEU A 1 447 ? 20.371  27.872  -35.846 1.000 30.247 0 551  LEU A HA   1 c 
ATOM   6893 H HB2  . LEU A 1 447 ? 20.488  29.708  -34.394 1.000 35.022 0 551  LEU A HB2  1 c 
ATOM   6894 H HB3  . LEU A 1 447 ? 19.679  30.620  -35.406 1.000 34.974 0 551  LEU A HB3  1 c 
ATOM   6895 H HG   . LEU A 1 447 ? 17.701  29.430  -34.930 1.000 38.077 0 551  LEU A HG   1 c 
ATOM   6896 H HD11 . LEU A 1 447 ? 18.472  27.362  -34.429 1.000 40.313 0 551  LEU A HD11 1 c 
ATOM   6897 H HD12 . LEU A 1 447 ? 17.862  27.886  -33.063 1.000 40.453 0 551  LEU A HD12 1 c 
ATOM   6898 H HD13 . LEU A 1 447 ? 19.431  27.908  -33.290 1.000 40.403 0 551  LEU A HD13 1 c 
ATOM   6899 H HD21 . LEU A 1 447 ? 18.200  31.341  -33.645 1.000 37.261 0 551  LEU A HD21 1 c 
ATOM   6900 H HD22 . LEU A 1 447 ? 19.013  30.456  -32.609 1.000 37.261 0 551  LEU A HD22 1 c 
ATOM   6901 H HD23 . LEU A 1 447 ? 17.440  30.287  -32.734 1.000 37.261 0 551  LEU A HD23 1 c 
ATOM   6902 N N    . THR A 1 448 ? 18.261  27.568  -37.233 1.000 25.104 0 552  THR A N    1 ? 
ATOM   6903 C CA   . THR A 1 448 ? 17.057  27.469  -38.044 1.000 24.280 0 552  THR A CA   1 ? 
ATOM   6904 C C    . THR A 1 448 ? 15.869  27.402  -37.095 1.000 23.821 0 552  THR A C    1 ? 
ATOM   6905 O O    . THR A 1 448 ? 15.881  26.639  -36.136 1.000 28.238 0 552  THR A O    1 ? 
ATOM   6906 C CB   . THR A 1 448 ? 17.081  26.219  -38.929 1.000 28.775 0 552  THR A CB   1 ? 
ATOM   6907 O OG1  . THR A 1 448 ? 18.200  26.390  -39.806 1.000 35.629 0 552  THR A OG1  1 ? 
ATOM   6908 C CG2  . THR A 1 448 ? 15.889  26.155  -39.864 1.000 29.937 0 552  THR A CG2  1 ? 
ATOM   6909 H H    . THR A 1 448 ? 18.486  26.865  -36.694 1.000 24.959 0 552  THR A H    1 c 
ATOM   6910 H HA   . THR A 1 448 ? 16.980  28.266  -38.610 1.000 25.095 0 552  THR A HA   1 c 
ATOM   6911 H HB   . THR A 1 448 ? 17.179  25.392  -38.399 1.000 29.329 0 552  THR A HB   1 c 
ATOM   6912 H HG1  . THR A 1 448 ? 18.092  27.110  -40.278 0.000 35.570 0 552  THR A HG1  1 c 
ATOM   6913 H HG21 . THR A 1 448 ? 15.928  25.334  -40.381 1.000 29.980 0 552  THR A HG21 1 c 
ATOM   6914 H HG22 . THR A 1 448 ? 15.906  26.917  -40.467 1.000 29.721 0 552  THR A HG22 1 c 
ATOM   6915 H HG23 . THR A 1 448 ? 15.066  26.171  -39.347 1.000 29.657 0 552  THR A HG23 1 c 
ATOM   6916 N N    . PHE A 1 449 ? 14.849  28.199  -37.363 1.000 20.082 0 553  PHE A N    1 ? 
ATOM   6917 C CA   . PHE A 1 449 ? 13.621  28.104  -36.613 1.000 18.251 0 553  PHE A CA   1 ? 
ATOM   6918 C C    . PHE A 1 449 ? 12.658  27.122  -37.257 1.000 18.028 0 553  PHE A C    1 ? 
ATOM   6919 O O    . PHE A 1 449 ? 12.464  27.136  -38.486 1.000 19.833 0 553  PHE A O    1 ? 
ATOM   6920 C CB   . PHE A 1 449 ? 12.904  29.448  -36.510 1.000 17.686 0 553  PHE A CB   1 ? 
ATOM   6921 C CG   . PHE A 1 449 ? 13.543  30.487  -35.604 1.000 16.946 0 553  PHE A CG   1 ? 
ATOM   6922 C CD1  . PHE A 1 449 ? 14.098  30.155  -34.377 1.000 17.526 0 553  PHE A CD1  1 ? 
ATOM   6923 C CD2  . PHE A 1 449 ? 13.576  31.816  -35.989 1.000 18.197 0 553  PHE A CD2  1 ? 
ATOM   6924 C CE1  . PHE A 1 449 ? 14.656  31.144  -33.548 1.000 17.792 0 553  PHE A CE1  1 ? 
ATOM   6925 C CE2  . PHE A 1 449 ? 14.040  32.810  -35.118 1.000 16.772 0 553  PHE A CE2  1 ? 
ATOM   6926 C CZ   . PHE A 1 449 ? 14.603  32.469  -33.913 1.000 18.641 0 553  PHE A CZ   1 ? 
ATOM   6927 H H    . PHE A 1 449 ? 14.916  28.821  -38.029 1.000 20.486 0 553  PHE A H    1 c 
ATOM   6928 H HA   . PHE A 1 449 ? 13.833  27.788  -35.697 1.000 18.482 0 553  PHE A HA   1 c 
ATOM   6929 H HB2  . PHE A 1 449 ? 12.833  29.825  -37.415 1.000 17.660 0 553  PHE A HB2  1 c 
ATOM   6930 H HB3  . PHE A 1 449 ? 11.988  29.283  -36.193 1.000 17.646 0 553  PHE A HB3  1 c 
ATOM   6931 H HD1  . PHE A 1 449 ? 14.112  29.254  -34.101 1.000 17.466 0 553  PHE A HD1  1 c 
ATOM   6932 H HD2  . PHE A 1 449 ? 13.151  32.070  -36.792 1.000 17.571 0 553  PHE A HD2  1 c 
ATOM   6933 H HE1  . PHE A 1 449 ? 15.018  30.901  -32.712 1.000 17.898 0 553  PHE A HE1  1 c 
ATOM   6934 H HE2  . PHE A 1 449 ? 14.054  33.710  -35.403 1.000 17.595 0 553  PHE A HE2  1 c 
ATOM   6935 H HZ   . PHE A 1 449 ? 14.990  33.131  -33.363 1.000 17.981 0 553  PHE A HZ   1 c 
ATOM   6936 N N    . GLN A 1 450 ? 12.039  26.332  -36.394 1.000 16.931 0 554  GLN A N    1 ? 
ATOM   6937 C CA   . GLN A 1 450 ? 10.980  25.401  -36.762 1.000 19.120 0 554  GLN A CA   1 ? 
ATOM   6938 C C    . GLN A 1 450 ? 9.589   25.990  -36.579 1.000 18.222 0 554  GLN A C    1 ? 
ATOM   6939 O O    . GLN A 1 450 ? 8.675   25.542  -37.288 1.000 20.585 0 554  GLN A O    1 ? 
ATOM   6940 C CB   . GLN A 1 450 ? 11.024  24.070  -36.003 1.000 21.635 0 554  GLN A CB   1 ? 
ATOM   6941 C CG   . GLN A 1 450 ? 12.342  23.330  -36.134 1.000 27.842 0 554  GLN A CG   1 ? 
ATOM   6942 C CD   . GLN A 1 450 ? 12.616  22.931  -37.547 1.000 37.062 0 554  GLN A CD   1 ? 
ATOM   6943 O OE1  . GLN A 1 450 ? 11.720  22.454  -38.254 1.000 42.102 0 554  GLN A OE1  1 ? 
ATOM   6944 N NE2  . GLN A 1 450 ? 13.827  23.233  -37.989 1.000 46.313 0 554  GLN A NE2  1 ? 
ATOM   6945 H H    . GLN A 1 450 ? 12.297  26.358  -35.518 1.000 17.663 0 554  GLN A H    1 c 
ATOM   6946 H HA   . GLN A 1 450 ? 11.087  25.190  -37.724 1.000 18.999 0 554  GLN A HA   1 c 
ATOM   6947 H HB2  . GLN A 1 450 ? 10.853  24.245  -35.054 1.000 22.283 0 554  GLN A HB2  1 c 
ATOM   6948 H HB3  . GLN A 1 450 ? 10.302  23.495  -36.333 1.000 22.348 0 554  GLN A HB3  1 c 
ATOM   6949 H HG2  . GLN A 1 450 ? 13.070  23.902  -35.811 1.000 28.207 0 554  GLN A HG2  1 c 
ATOM   6950 H HG3  . GLN A 1 450 ? 12.320  22.525  -35.574 1.000 28.125 0 554  GLN A HG3  1 c 
ATOM   6951 H HE21 . GLN A 1 450 ? 14.510  23.299  -37.414 1.000 42.921 0 554  GLN A HE21 1 c 
ATOM   6952 H HE22 . GLN A 1 450 ? 13.955  23.368  -38.865 1.000 43.163 0 554  GLN A HE22 1 c 
ATOM   6953 N N    . SER A 1 451 ? 9.402   26.921  -35.619 1.000 17.253 0 555  SER A N    1 ? 
ATOM   6954 C CA   . SER A 1 451 ? 8.101   27.459  -35.266 1.000 16.043 0 555  SER A CA   1 ? 
ATOM   6955 C C    . SER A 1 451 ? 7.769   28.667  -36.132 1.000 16.346 0 555  SER A C    1 ? 
ATOM   6956 O O    . SER A 1 451 ? 8.666   29.484  -36.402 1.000 15.605 0 555  SER A O    1 ? 
ATOM   6957 C CB   . SER A 1 451 ? 8.000   27.871  -33.813 1.000 16.094 0 555  SER A CB   1 ? 
ATOM   6958 O OG   . SER A 1 451 ? 8.720   29.048  -33.473 1.000 15.733 0 555  SER A OG   1 ? 
ATOM   6959 H H    . SER A 1 451 ? 10.132  27.231  -35.165 1.000 17.199 0 555  SER A H    1 c 
ATOM   6960 H HA   . SER A 1 451 ? 7.423   26.758  -35.437 1.000 16.387 0 555  SER A HA   1 c 
ATOM   6961 H HB2  . SER A 1 451 ? 7.059   28.005  -33.593 1.000 15.996 0 555  SER A HB2  1 c 
ATOM   6962 H HB3  . SER A 1 451 ? 8.323   27.135  -33.259 1.000 15.996 0 555  SER A HB3  1 c 
ATOM   6963 H HG   . SER A 1 451 ? 8.608   29.204  -32.648 0.000 15.710 0 555  SER A HG   1 c 
ATOM   6964 N N    . GLU A 1 452 ? 6.486   28.798  -36.524 1.000 16.427 0 556  GLU A N    1 ? 
ATOM   6965 C CA   . GLU A 1 452 ? 6.063   30.012  -37.221 1.000 16.425 0 556  GLU A CA   1 ? 
ATOM   6966 C C    . GLU A 1 452 ? 6.163   31.248  -36.323 1.000 17.000 0 556  GLU A C    1 ? 
ATOM   6967 O O    . GLU A 1 452 ? 6.468   32.338  -36.822 1.000 16.198 0 556  GLU A O    1 ? 
ATOM   6968 C CB   . GLU A 1 452 ? 4.678   29.864  -37.842 1.000 17.371 0 556  GLU A CB   1 ? 
ATOM   6969 C CG   . GLU A 1 452 ? 4.658   28.761  -38.902 1.000 20.125 0 556  GLU A CG   1 ? 
ATOM   6970 C CD   . GLU A 1 452 ? 5.634   28.940  -40.043 1.000 20.247 0 556  GLU A CD   1 ? 
ATOM   6971 O OE1  . GLU A 1 452 ? 5.810   30.100  -40.531 1.000 17.536 0 556  GLU A OE1  1 ? 
ATOM   6972 O OE2  . GLU A 1 452 ? 6.242   27.932  -40.489 1.000 21.696 0 556  GLU A OE2  1 ? 
ATOM   6973 H H    . GLU A 1 452 ? 5.876   28.138  -36.356 1.000 16.449 0 556  GLU A H    1 c 
ATOM   6974 H HA   . GLU A 1 452 ? 6.694   30.152  -37.972 1.000 16.716 0 556  GLU A HA   1 c 
ATOM   6975 H HB2  . GLU A 1 452 ? 4.030   29.657  -37.136 1.000 17.731 0 556  GLU A HB2  1 c 
ATOM   6976 H HB3  . GLU A 1 452 ? 4.419   30.715  -38.249 1.000 17.735 0 556  GLU A HB3  1 c 
ATOM   6977 H HG2  . GLU A 1 452 ? 4.846   27.902  -38.468 1.000 19.467 0 556  GLU A HG2  1 c 
ATOM   6978 H HG3  . GLU A 1 452 ? 3.754   28.703  -39.278 1.000 19.487 0 556  GLU A HG3  1 c 
ATOM   6979 N N    . LYS A 1 453 ? 5.905   31.116  -35.029 1.000 14.837 0 557  LYS A N    1 ? 
ATOM   6980 C CA   . LYS A 1 453 ? 6.046   32.274  -34.150 1.000 14.873 0 557  LYS A CA   1 ? 
ATOM   6981 C C    . LYS A 1 453 ? 7.440   32.878  -34.222 1.000 16.498 0 557  LYS A C    1 ? 
ATOM   6982 O O    . LYS A 1 453 ? 7.593   34.087  -34.309 1.000 17.336 0 557  LYS A O    1 ? 
ATOM   6983 C CB   . LYS A 1 453 ? 5.548   31.974  -32.743 1.000 16.334 0 557  LYS A CB   1 ? 
ATOM   6984 C CG   . LYS A 1 453 ? 4.043   32.069  -32.568 1.000 16.201 0 557  LYS A CG   1 ? 
ATOM   6985 C CD   . LYS A 1 453 ? 3.531   31.822  -31.156 1.000 16.997 0 557  LYS A CD   1 ? 
ATOM   6986 C CE   . LYS A 1 453 ? 2.023   31.935  -31.069 1.000 17.934 0 557  LYS A CE   1 ? 
ATOM   6987 N NZ   . LYS A 1 453 ? 1.530   31.728  -29.712 1.000 18.982 0 557  LYS A NZ   1 ? 
ATOM   6988 H H    . LYS A 1 453 ? 5.634   30.314  -34.684 1.000 15.361 0 557  LYS A H    1 c 
ATOM   6989 H HA   . LYS A 1 453 ? 5.427   32.967  -34.495 1.000 15.458 0 557  LYS A HA   1 c 
ATOM   6990 H HB2  . LYS A 1 453 ? 5.833   31.069  -32.494 1.000 15.955 0 557  LYS A HB2  1 c 
ATOM   6991 H HB3  . LYS A 1 453 ? 5.972   32.602  -32.119 1.000 15.961 0 557  LYS A HB3  1 c 
ATOM   6992 H HG2  . LYS A 1 453 ? 3.756   32.964  -32.853 1.000 16.425 0 557  LYS A HG2  1 c 
ATOM   6993 H HG3  . LYS A 1 453 ? 3.621   31.421  -33.174 1.000 16.439 0 557  LYS A HG3  1 c 
ATOM   6994 H HD2  . LYS A 1 453 ? 3.803   30.923  -30.867 1.000 17.022 0 557  LYS A HD2  1 c 
ATOM   6995 H HD3  . LYS A 1 453 ? 3.939   32.475  -30.547 1.000 17.029 0 557  LYS A HD3  1 c 
ATOM   6996 H HE2  . LYS A 1 453 ? 1.748   32.818  -31.373 1.000 17.959 0 557  LYS A HE2  1 c 
ATOM   6997 H HE3  . LYS A 1 453 ? 1.616   31.273  -31.656 1.000 17.960 0 557  LYS A HE3  1 c 
ATOM   6998 H HZ1  . LYS A 1 453 ? 1.822   32.396  -29.175 1.000 18.658 0 557  LYS A HZ1  1 c 
ATOM   6999 H HZ2  . LYS A 1 453 ? 1.832   30.936  -29.394 1.000 18.673 0 557  LYS A HZ2  1 c 
ATOM   7000 H HZ3  . LYS A 1 453 ? 0.623   31.722  -29.714 1.000 18.658 0 557  LYS A HZ3  1 c 
ATOM   7001 N N    . MET A 1 454 ? 8.482   32.052  -34.055 1.000 15.738 0 558  MET A N    1 ? 
ATOM   7002 C CA   . MET A 1 454 ? 9.830   32.603  -34.037 1.000 14.459 0 558  MET A CA   1 ? 
ATOM   7003 C C    . MET A 1 454 ? 10.279  33.073  -35.421 1.000 15.662 0 558  MET A C    1 ? 
ATOM   7004 O O    . MET A 1 454 ? 10.961  34.082  -35.520 1.000 16.627 0 558  MET A O    1 ? 
ATOM   7005 C CB   . MET A 1 454 ? 10.817  31.636  -33.380 1.000 15.008 0 558  MET A CB   1 ? 
ATOM   7006 C CG   . MET A 1 454 ? 10.499  31.367  -31.929 1.000 16.203 0 558  MET A CG   1 ? 
ATOM   7007 S SD   . MET A 1 454 ? 10.488  32.795  -30.830 1.000 17.095 0 558  MET A SD   1 ? 
ATOM   7008 C CE   . MET A 1 454 ? 12.235  33.167  -30.723 1.000 17.681 0 558  MET A CE   1 ? 
ATOM   7009 H H    . MET A 1 454 ? 8.357   31.152  -33.952 1.000 15.604 0 558  MET A H    1 c 
ATOM   7010 H HA   . MET A 1 454 ? 9.793   33.416  -33.473 1.000 15.120 0 558  MET A HA   1 c 
ATOM   7011 H HB2  . MET A 1 454 ? 10.806  30.789  -33.875 1.000 15.147 0 558  MET A HB2  1 c 
ATOM   7012 H HB3  . MET A 1 454 ? 11.720  32.012  -33.447 1.000 15.146 0 558  MET A HB3  1 c 
ATOM   7013 H HG2  . MET A 1 454 ? 9.623   30.937  -31.876 1.000 16.063 0 558  MET A HG2  1 c 
ATOM   7014 H HG3  . MET A 1 454 ? 11.154  30.731  -31.584 1.000 16.055 0 558  MET A HG3  1 c 
ATOM   7015 H HE1  . MET A 1 454 ? 12.367  33.940  -30.143 1.000 17.532 0 558  MET A HE1  1 c 
ATOM   7016 H HE2  . MET A 1 454 ? 12.709  32.399  -30.354 1.000 17.532 0 558  MET A HE2  1 c 
ATOM   7017 H HE3  . MET A 1 454 ? 12.580  33.365  -31.613 1.000 17.532 0 558  MET A HE3  1 c 
ATOM   7018 N N    . LYS A 1 455 ? 9.841   32.404  -36.500 1.000 15.799 0 559  LYS A N    1 ? 
ATOM   7019 C CA   . LYS A 1 455 ? 10.172  32.882  -37.835 1.000 15.919 0 559  LYS A CA   1 ? 
ATOM   7020 C C    . LYS A 1 455 ? 9.671   34.319  -38.033 1.000 16.927 0 559  LYS A C    1 ? 
ATOM   7021 O O    . LYS A 1 455 ? 10.354  35.138  -38.646 1.000 18.165 0 559  LYS A O    1 ? 
ATOM   7022 C CB   . LYS A 1 455 ? 9.525   31.964  -38.882 1.000 17.239 0 559  LYS A CB   1 ? 
ATOM   7023 C CG   . LYS A 1 455 ? 10.146  30.596  -39.027 1.000 18.487 0 559  LYS A CG   1 ? 
ATOM   7024 C CD   . LYS A 1 455 ? 9.313   29.741  -39.985 1.000 18.287 0 559  LYS A CD   1 ? 
ATOM   7025 C CE   . LYS A 1 455 ? 9.822   28.321  -40.053 1.000 20.733 0 559  LYS A CE   1 ? 
ATOM   7026 N NZ   . LYS A 1 455 ? 9.029   27.647  -41.087 1.000 20.892 0 559  LYS A NZ   1 ? 
ATOM   7027 H H    . LYS A 1 455 ? 9.341   31.645  -36.404 1.000 15.812 0 559  LYS A H    1 c 
ATOM   7028 H HA   . LYS A 1 455 ? 11.157  32.865  -37.942 1.000 16.308 0 559  LYS A HA   1 c 
ATOM   7029 H HB2  . LYS A 1 455 ? 8.578   31.849  -38.651 1.000 17.208 0 559  LYS A HB2  1 c 
ATOM   7030 H HB3  . LYS A 1 455 ? 9.563   32.412  -39.754 1.000 17.207 0 559  LYS A HB3  1 c 
ATOM   7031 H HG2  . LYS A 1 455 ? 11.059  30.691  -39.378 1.000 18.145 0 559  LYS A HG2  1 c 
ATOM   7032 H HG3  . LYS A 1 455 ? 10.190  30.163  -38.148 1.000 18.131 0 559  LYS A HG3  1 c 
ATOM   7033 H HD2  . LYS A 1 455 ? 8.379   29.734  -39.684 1.000 18.866 0 559  LYS A HD2  1 c 
ATOM   7034 H HD3  . LYS A 1 455 ? 9.345   30.139  -40.882 1.000 18.881 0 559  LYS A HD3  1 c 
ATOM   7035 H HE2  . LYS A 1 455 ? 10.765  28.304  -40.296 1.000 20.193 0 559  LYS A HE2  1 c 
ATOM   7036 H HE3  . LYS A 1 455 ? 9.701   27.870  -39.198 1.000 20.193 0 559  LYS A HE3  1 c 
ATOM   7037 H HZ1  . LYS A 1 455 ? 9.087   28.094  -41.871 1.000 20.808 0 559  LYS A HZ1  1 c 
ATOM   7038 H HZ2  . LYS A 1 455 ? 8.161   27.610  -40.831 1.000 20.820 0 559  LYS A HZ2  1 c 
ATOM   7039 H HZ3  . LYS A 1 455 ? 9.338   26.803  -41.205 1.000 20.832 0 559  LYS A HZ3  1 c 
ATOM   7040 N N    . GLY A 1 456 ? 8.464   34.606  -37.544 1.000 16.081 0 560  GLY A N    1 ? 
ATOM   7041 C CA   . GLY A 1 456 ? 7.899   35.944  -37.683 1.000 18.329 0 560  GLY A CA   1 ? 
ATOM   7042 C C    . GLY A 1 456 ? 8.567   36.976  -36.777 1.000 20.039 0 560  GLY A C    1 ? 
ATOM   7043 O O    . GLY A 1 456 ? 8.446   38.174  -37.014 1.000 22.406 0 560  GLY A O    1 ? 
ATOM   7044 H H    . GLY A 1 456 ? 7.975   33.960  -37.121 1.000 16.751 0 560  GLY A H    1 c 
ATOM   7045 H HA2  . GLY A 1 456 ? 7.988   36.231  -38.622 1.000 18.116 0 560  GLY A HA2  1 c 
ATOM   7046 H HA3  . GLY A 1 456 ? 6.937   35.905  -37.474 1.000 18.115 0 560  GLY A HA3  1 c 
ATOM   7047 N N    A MET A 1 457 ? 9.321   36.509  -35.781 0.500 17.798 0 561  MET A N    1 ? 
ATOM   7048 N N    B MET A 1 457 ? 9.301   36.474  -35.772 0.500 21.144 0 561  MET A N    1 ? 
ATOM   7049 C CA   A MET A 1 457 ? 9.929   37.401  -34.805 0.500 18.187 0 561  MET A CA   1 ? 
ATOM   7050 C CA   B MET A 1 457 ? 9.988   37.263  -34.754 0.500 24.606 0 561  MET A CA   1 ? 
ATOM   7051 C C    A MET A 1 457 ? 11.363  37.746  -35.199 0.500 19.432 0 561  MET A C    1 ? 
ATOM   7052 C C    B MET A 1 457 ? 11.348  37.759  -35.222 0.500 22.845 0 561  MET A C    1 ? 
ATOM   7053 O O    A MET A 1 457 ? 11.987  38.573  -34.539 0.500 19.335 0 561  MET A O    1 ? 
ATOM   7054 O O    B MET A 1 457 ? 11.927  38.637  -34.587 0.500 22.938 0 561  MET A O    1 ? 
ATOM   7055 C CB   A MET A 1 457 ? 9.859   36.729  -33.419 0.500 16.341 0 561  MET A CB   1 ? 
ATOM   7056 C CB   B MET A 1 457 ? 10.287  36.373  -33.533 0.500 27.208 0 561  MET A CB   1 ? 
ATOM   7057 C CG   A MET A 1 457 ? 9.967   37.683  -32.245 0.500 15.781 0 561  MET A CG   1 ? 
ATOM   7058 C CG   B MET A 1 457 ? 10.453  37.105  -32.220 0.500 30.829 0 561  MET A CG   1 ? 
ATOM   7059 S SD   A MET A 1 457 ? 10.056  36.697  -30.732 0.500 13.820 0 561  MET A SD   1 ? 
ATOM   7060 S SD   B MET A 1 457 ? 8.864   37.600  -31.523 0.500 31.111 0 561  MET A SD   1 ? 
ATOM   7061 C CE   A MET A 1 457 ? 8.363   36.094  -30.629 0.500 13.636 0 561  MET A CE   1 ? 
ATOM   7062 C CE   B MET A 1 457 ? 8.554   36.196  -30.446 0.500 30.178 0 561  MET A CE   1 ? 
ATOM   7063 H H    A MET A 1 457 ? 9.450   35.610  -35.692 0.500 18.351 0 561  MET A H    1 c 
ATOM   7064 H H    B MET A 1 457 ? 9.364   35.566  -35.705 0.500 21.459 0 561  MET A H    1 c 
ATOM   7065 H HA   A MET A 1 457 ? 9.404   38.241  -34.782 0.500 18.017 0 561  MET A HA   1 c 
ATOM   7066 H HA   B MET A 1 457 ? 9.418   38.031  -34.492 0.500 23.990 0 561  MET A HA   1 c 
ATOM   7067 H HB2  A MET A 1 457 ? 9.009   36.243  -33.353 0.500 16.607 0 561  MET A HB2  1 c 
ATOM   7068 H HB2  B MET A 1 457 ? 9.557   35.725  -33.440 0.500 27.179 0 561  MET A HB2  1 c 
ATOM   7069 H HB3  A MET A 1 457 ? 10.582  36.070  -33.357 0.500 16.607 0 561  MET A HB3  1 c 
ATOM   7070 H HB3  B MET A 1 457 ? 11.108  35.869  -33.714 0.500 27.261 0 561  MET A HB3  1 c 
ATOM   7071 H HG2  A MET A 1 457 ? 10.772  38.233  -32.328 0.500 15.519 0 561  MET A HG2  1 c 
ATOM   7072 H HG2  B MET A 1 457 ? 10.913  36.526  -31.581 0.500 29.930 0 561  MET A HG2  1 c 
ATOM   7073 H HG3  A MET A 1 457 ? 9.186   38.270  -32.211 0.500 15.519 0 561  MET A HG3  1 c 
ATOM   7074 H HG3  B MET A 1 457 ? 11.001  37.902  -32.358 0.500 29.931 0 561  MET A HG3  1 c 
ATOM   7075 H HE1  A MET A 1 457 ? 8.267   35.530  -29.840 0.500 13.719 0 561  MET A HE1  1 c 
ATOM   7076 H HE1  B MET A 1 457 ? 7.709   36.327  -29.977 0.500 30.265 0 561  MET A HE1  1 c 
ATOM   7077 H HE2  A MET A 1 457 ? 7.752   36.851  -30.565 0.500 13.691 0 561  MET A HE2  1 c 
ATOM   7078 H HE2  B MET A 1 457 ? 8.508   35.381  -30.980 0.500 30.349 0 561  MET A HE2  1 c 
ATOM   7079 H HE3  A MET A 1 457 ? 8.154   35.575  -31.427 0.500 13.691 0 561  MET A HE3  1 c 
ATOM   7080 H HE3  B MET A 1 457 ? 9.278   36.119  -29.797 0.500 30.256 0 561  MET A HE3  1 c 
ATOM   7081 N N    . LYS A 1 458 ? 11.897  37.128  -36.262 1.000 20.513 0 562  LYS A N    1 ? 
ATOM   7082 C CA   . LYS A 1 458 ? 13.314  37.165  -36.558 1.000 23.621 0 562  LYS A CA   1 ? 
ATOM   7083 C C    . LYS A 1 458 ? 13.860  38.598  -36.658 1.000 27.708 0 562  LYS A C    1 ? 
ATOM   7084 O O    . LYS A 1 458 ? 14.902  38.899  -36.075 1.000 27.167 0 562  LYS A O    1 ? 
ATOM   7085 C CB   . LYS A 1 458 ? 13.572  36.277  -37.773 1.000 29.810 0 562  LYS A CB   1 ? 
ATOM   7086 C CG   . LYS A 1 458 ? 14.502  36.810  -38.813 1.000 41.204 0 562  LYS A CG   1 ? 
ATOM   7087 C CD   . LYS A 1 458 ? 14.376  36.049  -40.130 1.000 56.589 0 562  LYS A CD   1 ? 
ATOM   7088 C CE   . LYS A 1 458 ? 15.327  36.490  -41.218 1.000 64.182 0 562  LYS A CE   1 ? 
ATOM   7089 N NZ   . LYS A 1 458 ? 16.689  35.970  -41.037 1.000 66.248 0 562  LYS A NZ   1 ? 
ATOM   7090 H H    . LYS A 1 458 ? 11.353  36.659  -36.826 1.000 21.344 0 562  LYS A H    1 c 
ATOM   7091 H HA   . LYS A 1 458 ? 13.780  36.732  -35.800 1.000 24.748 0 562  LYS A HA   1 c 
ATOM   7092 H HB2  . LYS A 1 458 ? 13.932  35.423  -37.453 1.000 30.508 0 562  LYS A HB2  1 c 
ATOM   7093 H HB3  . LYS A 1 458 ? 12.714  36.087  -38.207 1.000 30.486 0 562  LYS A HB3  1 c 
ATOM   7094 H HG2  . LYS A 1 458 ? 14.302  37.757  -38.970 1.000 40.873 0 562  LYS A HG2  1 c 
ATOM   7095 H HG3  . LYS A 1 458 ? 15.424  36.739  -38.483 1.000 41.010 0 562  LYS A HG3  1 c 
ATOM   7096 H HD2  . LYS A 1 458 ? 14.516  35.093  -39.955 1.000 54.111 0 562  LYS A HD2  1 c 
ATOM   7097 H HD3  . LYS A 1 458 ? 13.458  36.158  -40.458 1.000 53.866 0 562  LYS A HD3  1 c 
ATOM   7098 H HE2  . LYS A 1 458 ? 14.988  36.188  -42.080 1.000 62.840 0 562  LYS A HE2  1 c 
ATOM   7099 H HE3  . LYS A 1 458 ? 15.363  37.463  -41.235 1.000 62.840 0 562  LYS A HE3  1 c 
ATOM   7100 H HZ1  . LYS A 1 458 ? 16.674  35.065  -41.035 1.000 65.605 0 562  LYS A HZ1  1 c 
ATOM   7101 H HZ2  . LYS A 1 458 ? 17.027  36.264  -40.250 1.000 65.605 0 562  LYS A HZ2  1 c 
ATOM   7102 H HZ3  . LYS A 1 458 ? 17.219  36.258  -41.714 1.000 65.605 0 562  LYS A HZ3  1 c 
ATOM   7103 N N    . GLU A 1 459 ? 13.198  39.481  -37.403 1.000 27.314 0 563  GLU A N    1 ? 
ATOM   7104 C CA   . GLU A 1 459 ? 13.741  40.823  -37.590 1.000 30.645 0 563  GLU A CA   1 ? 
ATOM   7105 C C    . GLU A 1 459 ? 13.702  41.641  -36.296 1.000 29.906 0 563  GLU A C    1 ? 
ATOM   7106 O O    . GLU A 1 459 ? 14.667  42.369  -36.019 1.000 34.017 0 563  GLU A O    1 ? 
ATOM   7107 C CB   . GLU A 1 459 ? 13.092  41.563  -38.765 1.000 32.546 0 563  GLU A CB   1 ? 
ATOM   7108 C CG   . GLU A 1 459 ? 13.443  40.911  -40.099 1.000 36.697 0 563  GLU A CG   1 ? 
ATOM   7109 C CD   . GLU A 1 459 ? 12.553  39.726  -40.446 1.000 40.972 0 563  GLU A CD   1 ? 
ATOM   7110 O OE1  . GLU A 1 459 ? 12.901  39.012  -41.416 1.000 48.172 0 563  GLU A OE1  1 ? 
ATOM   7111 O OE2  . GLU A 1 459 ? 11.553  39.486  -39.707 1.000 43.266 0 563  GLU A OE2  1 ? 
ATOM   7112 H H    . GLU A 1 459 ? 12.400  39.258  -37.787 1.000 28.125 0 563  GLU A H    1 c 
ATOM   7113 H HA   . GLU A 1 459 ? 14.696  40.719  -37.834 1.000 30.232 0 563  GLU A HA   1 c 
ATOM   7114 H HB2  . GLU A 1 459 ? 12.121  41.579  -38.637 1.000 33.081 0 563  GLU A HB2  1 c 
ATOM   7115 H HB3  . GLU A 1 459 ? 13.408  42.490  -38.769 1.000 32.995 0 563  GLU A HB3  1 c 
ATOM   7116 H HG2  . GLU A 1 459 ? 13.367  41.579  -40.812 1.000 36.607 0 563  GLU A HG2  1 c 
ATOM   7117 H HG3  . GLU A 1 459 ? 14.375  40.606  -40.074 1.000 36.538 0 563  GLU A HG3  1 c 
ATOM   7118 N N    . LEU A 1 460 ? 12.719  41.404  -35.425 1.000 22.318 0 564  LEU A N    1 ? 
ATOM   7119 C CA   . LEU A 1 460 ? 12.596  42.082  -34.140 1.000 22.987 0 564  LEU A CA   1 ? 
ATOM   7120 C C    . LEU A 1 460 ? 13.706  41.665  -33.167 1.000 23.796 0 564  LEU A C    1 ? 
ATOM   7121 O O    . LEU A 1 460 ? 14.020  42.391  -32.214 1.000 24.304 0 564  LEU A O    1 ? 
ATOM   7122 C CB   . LEU A 1 460 ? 11.224  41.826  -33.540 1.000 26.034 0 564  LEU A CB   1 ? 
ATOM   7123 C CG   . LEU A 1 460 ? 10.071  42.176  -34.488 1.000 30.121 0 564  LEU A CG   1 ? 
ATOM   7124 C CD1  . LEU A 1 460 ? 8.830   41.622  -33.877 1.000 26.868 0 564  LEU A CD1  1 ? 
ATOM   7125 C CD2  . LEU A 1 460 ? 10.021  43.684  -34.690 1.000 30.029 0 564  LEU A CD2  1 ? 
ATOM   7126 H H    . LEU A 1 460 ? 12.098  40.769  -35.638 1.000 24.239 0 564  LEU A H    1 c 
ATOM   7127 H HA   . LEU A 1 460 ? 12.693  43.054  -34.304 1.000 23.669 0 564  LEU A HA   1 c 
ATOM   7128 H HB2  . LEU A 1 460 ? 11.161  40.872  -33.303 1.000 26.151 0 564  LEU A HB2  1 c 
ATOM   7129 H HB3  . LEU A 1 460 ? 11.136  42.364  -32.720 1.000 26.173 0 564  LEU A HB3  1 c 
ATOM   7130 H HG   . LEU A 1 460 ? 10.222  41.738  -35.361 1.000 28.633 0 564  LEU A HG   1 c 
ATOM   7131 H HD11 . LEU A 1 460 ? 8.898   40.654  -33.822 1.000 27.794 0 564  LEU A HD11 1 c 
ATOM   7132 H HD12 . LEU A 1 460 ? 8.064   41.861  -34.425 1.000 27.803 0 564  LEU A HD12 1 c 
ATOM   7133 H HD13 . LEU A 1 460 ? 8.715   41.989  -32.984 1.000 27.795 0 564  LEU A HD13 1 c 
ATOM   7134 H HD21 . LEU A 1 460 ? 10.793  43.970  -35.207 1.000 29.957 0 564  LEU A HD21 1 c 
ATOM   7135 H HD22 . LEU A 1 460 ? 10.028  44.129  -33.826 1.000 30.005 0 564  LEU A HD22 1 c 
ATOM   7136 H HD23 . LEU A 1 460 ? 9.208   43.921  -35.168 1.000 30.027 0 564  LEU A HD23 1 c 
ATOM   7137 N N    . LEU A 1 461 ? 14.285  40.479  -33.388 1.000 24.341 0 565  LEU A N    1 ? 
ATOM   7138 C CA   . LEU A 1 461 ? 15.155  39.880  -32.372 1.000 24.271 0 565  LEU A CA   1 ? 
ATOM   7139 C C    . LEU A 1 461 ? 16.521  40.521  -32.412 1.000 27.453 0 565  LEU A C    1 ? 
ATOM   7140 O O    . LEU A 1 461 ? 17.259  40.419  -31.430 1.000 27.317 0 565  LEU A O    1 ? 
ATOM   7141 C CB   . LEU A 1 461 ? 15.336  38.383  -32.627 1.000 25.195 0 565  LEU A CB   1 ? 
ATOM   7142 C CG   . LEU A 1 461 ? 14.113  37.563  -32.285 1.000 24.840 0 565  LEU A CG   1 ? 
ATOM   7143 C CD1  . LEU A 1 461 ? 14.279  36.132  -32.809 1.000 27.696 0 565  LEU A CD1  1 ? 
ATOM   7144 C CD2  . LEU A 1 461 ? 13.719  37.560  -30.848 1.000 26.109 0 565  LEU A CD2  1 ? 
ATOM   7145 H H    . LEU A 1 461 ? 14.135  40.029  -34.169 1.000 24.284 0 565  LEU A H    1 c 
ATOM   7146 H HA   . LEU A 1 461 ? 14.752  40.022  -31.478 1.000 25.012 0 565  LEU A HA   1 c 
ATOM   7147 H HB2  . LEU A 1 461 ? 15.549  38.251  -33.580 1.000 24.940 0 565  LEU A HB2  1 c 
ATOM   7148 H HB3  . LEU A 1 461 ? 16.092  38.062  -32.085 1.000 24.933 0 565  LEU A HB3  1 c 
ATOM   7149 H HG   . LEU A 1 461 ? 13.352  37.957  -32.776 1.000 25.617 0 565  LEU A HG   1 c 
ATOM   7150 H HD11 . LEU A 1 461 ? 14.482  36.155  -33.758 1.000 26.794 0 565  LEU A HD11 1 c 
ATOM   7151 H HD12 . LEU A 1 461 ? 13.455  35.636  -32.667 1.000 26.811 0 565  LEU A HD12 1 c 
ATOM   7152 H HD13 . LEU A 1 461 ? 15.005  35.694  -32.334 1.000 26.817 0 565  LEU A HD13 1 c 
ATOM   7153 H HD21 . LEU A 1 461 ? 13.338  38.423  -30.613 1.000 25.709 0 565  LEU A HD21 1 c 
ATOM   7154 H HD22 . LEU A 1 461 ? 14.503  37.392  -30.297 1.000 25.713 0 565  LEU A HD22 1 c 
ATOM   7155 H HD23 . LEU A 1 461 ? 13.060  36.863  -30.691 1.000 25.693 0 565  LEU A HD23 1 c 
ATOM   7156 N N    . VAL A 1 462 ? 16.878  41.040  -33.586 1.000 32.814 0 566  VAL A N    1 ? 
ATOM   7157 C CA   . VAL A 1 462 ? 18.247  41.453  -33.856 1.000 39.980 0 566  VAL A CA   1 ? 
ATOM   7158 C C    . VAL A 1 462 ? 18.309  42.970  -34.014 1.000 40.863 0 566  VAL A C    1 ? 
ATOM   7159 O O    . VAL A 1 462 ? 19.328  43.482  -34.456 1.000 44.478 0 566  VAL A O    1 ? 
ATOM   7160 C CB   . VAL A 1 462 ? 18.819  40.725  -35.089 1.000 33.948 0 566  VAL A CB   1 ? 
ATOM   7161 C CG1  . VAL A 1 462 ? 18.892  39.217  -34.858 1.000 36.929 0 566  VAL A CG1  1 ? 
ATOM   7162 C CG2  . VAL A 1 462 ? 18.035  41.010  -36.372 1.000 39.805 0 566  VAL A CG2  1 ? 
ATOM   7163 H H    . VAL A 1 462 ? 16.253  41.139  -34.245 1.000 32.748 0 566  VAL A H    1 c 
ATOM   7164 H HA   . VAL A 1 462 ? 18.794  41.210  -33.085 1.000 37.347 0 566  VAL A HA   1 c 
ATOM   7165 H HB   . VAL A 1 462 ? 19.740  41.052  -35.219 1.000 36.650 0 566  VAL A HB   1 c 
ATOM   7166 H HG11 . VAL A 1 462 ? 17.996  38.865  -34.723 1.000 35.973 0 566  VAL A HG11 1 c 
ATOM   7167 H HG12 . VAL A 1 462 ? 19.433  39.034  -34.071 1.000 35.875 0 566  VAL A HG12 1 c 
ATOM   7168 H HG13 . VAL A 1 462 ? 19.294  38.789  -35.633 1.000 35.987 0 566  VAL A HG13 1 c 
ATOM   7169 H HG21 . VAL A 1 462 ? 18.452  40.544  -37.116 1.000 37.972 0 566  VAL A HG21 1 c 
ATOM   7170 H HG22 . VAL A 1 462 ? 18.037  41.966  -36.550 1.000 37.985 0 566  VAL A HG22 1 c 
ATOM   7171 H HG23 . VAL A 1 462 ? 17.120  40.701  -36.271 1.000 37.919 0 566  VAL A HG23 1 c 
ATOM   7172 N N    . ALA A 1 463 ? 17.220  43.663  -33.663 1.000 43.384 0 567  ALA A N    1 ? 
ATOM   7173 C CA   . ALA A 1 463 ? 17.139  45.111  -33.765 1.000 45.026 0 567  ALA A CA   1 ? 
ATOM   7174 C C    . ALA A 1 463 ? 17.793  45.770  -32.553 1.000 45.186 0 567  ALA A C    1 ? 
ATOM   7175 O O    . ALA A 1 463 ? 17.667  45.287  -31.421 1.000 40.659 0 567  ALA A O    1 ? 
ATOM   7176 C CB   . ALA A 1 463 ? 15.694  45.533  -33.903 1.000 42.811 0 567  ALA A CB   1 ? 
ATOM   7177 H H    . ALA A 1 463 ? 16.495  43.214  -33.337 1.000 42.806 0 567  ALA A H    1 c 
ATOM   7178 H HA   . ALA A 1 463 ? 17.638  45.394  -34.580 1.000 44.367 0 567  ALA A HA   1 c 
ATOM   7179 H HB1  . ALA A 1 463 ? 15.312  45.134  -34.703 1.000 43.456 0 567  ALA A HB1  1 c 
ATOM   7180 H HB2  . ALA A 1 463 ? 15.191  45.238  -33.125 1.000 43.456 0 567  ALA A HB2  1 c 
ATOM   7181 H HB3  . ALA A 1 463 ? 15.642  46.502  -33.971 1.000 43.456 0 567  ALA A HB3  1 c 
ATOM   7182 N N    . THR A 1 464 ? 18.443  46.931  -32.791 1.000 51.412 0 568  THR A N    1 ? 
ATOM   7183 C CA   . THR A 1 464 ? 19.279  47.573  -31.780 1.000 47.325 0 568  THR A CA   1 ? 
ATOM   7184 C C    . THR A 1 464 ? 18.464  47.801  -30.515 1.000 42.767 0 568  THR A C    1 ? 
ATOM   7185 O O    . THR A 1 464 ? 18.963  47.635  -29.406 1.000 43.485 0 568  THR A O    1 ? 
ATOM   7186 C CB   . THR A 1 464 ? 19.874  48.884  -32.305 1.000 55.649 0 568  THR A CB   1 ? 
ATOM   7187 O OG1  . THR A 1 464 ? 20.572  48.574  -33.509 1.000 56.636 0 568  THR A OG1  1 ? 
ATOM   7188 C CG2  . THR A 1 464 ? 20.800  49.545  -31.297 1.000 55.351 0 568  THR A CG2  1 ? 
ATOM   7189 H H    . THR A 1 464 ? 18.357  47.331  -33.608 1.000 48.909 0 568  THR A H    1 c 
ATOM   7190 H HA   . THR A 1 464 ? 20.019  46.964  -31.566 1.000 48.627 0 568  THR A HA   1 c 
ATOM   7191 H HB   . THR A 1 464 ? 19.139  49.510  -32.512 1.000 54.167 0 568  THR A HB   1 c 
ATOM   7192 H HG1  . THR A 1 464 ? 21.183  47.995  -33.338 0.000 56.490 0 568  THR A HG1  1 c 
ATOM   7193 H HG21 . THR A 1 464 ? 21.250  50.298  -31.716 1.000 55.421 0 568  THR A HG21 1 c 
ATOM   7194 H HG22 . THR A 1 464 ? 21.463  48.901  -30.994 1.000 55.421 0 568  THR A HG22 1 c 
ATOM   7195 H HG23 . THR A 1 464 ? 20.284  49.861  -30.537 1.000 55.364 0 568  THR A HG23 1 c 
ATOM   7196 N N    . LYS A 1 465 ? 17.197  48.186  -30.695 1.000 43.580 0 569  LYS A N    1 ? 
ATOM   7197 C CA   . LYS A 1 465 ? 16.289  48.488  -29.596 1.000 47.277 0 569  LYS A CA   1 ? 
ATOM   7198 C C    . LYS A 1 465 ? 15.137  47.496  -29.676 1.000 42.901 0 569  LYS A C    1 ? 
ATOM   7199 O O    . LYS A 1 465 ? 14.576  47.342  -30.756 1.000 41.936 0 569  LYS A O    1 ? 
ATOM   7200 C CB   . LYS A 1 465 ? 15.801  49.943  -29.694 1.000 55.255 0 569  LYS A CB   1 ? 
ATOM   7201 C CG   . LYS A 1 465 ? 15.957  50.603  -31.066 1.000 62.208 0 569  LYS A CG   1 ? 
ATOM   7202 C CD   . LYS A 1 465 ? 16.493  52.036  -31.033 1.000 79.045 0 569  LYS A CD   1 ? 
ATOM   7203 C CE   . LYS A 1 465 ? 17.990  52.079  -30.851 1.000 86.818 0 569  LYS A CE   1 ? 
ATOM   7204 N NZ   . LYS A 1 465 ? 18.486  53.385  -30.403 1.000 92.836 0 569  LYS A NZ   1 ? 
ATOM   7205 H H    . LYS A 1 465 ? 16.872  48.228  -31.548 1.000 44.537 0 569  LYS A H    1 c 
ATOM   7206 H HA   . LYS A 1 465 ? 16.769  48.360  -28.739 1.000 46.837 0 569  LYS A HA   1 c 
ATOM   7207 H HB2  . LYS A 1 465 ? 14.852  49.971  -29.448 1.000 54.745 0 569  LYS A HB2  1 c 
ATOM   7208 H HB3  . LYS A 1 465 ? 16.293  50.480  -29.036 1.000 54.900 0 569  LYS A HB3  1 c 
ATOM   7209 H HG2  . LYS A 1 465 ? 16.568  50.064  -31.605 1.000 63.451 0 569  LYS A HG2  1 c 
ATOM   7210 H HG3  . LYS A 1 465 ? 15.084  50.601  -31.515 1.000 63.851 0 569  LYS A HG3  1 c 
ATOM   7211 H HD2  . LYS A 1 465 ? 16.259  52.488  -31.873 1.000 76.502 0 569  LYS A HD2  1 c 
ATOM   7212 H HD3  . LYS A 1 465 ? 16.066  52.522  -30.295 1.000 76.499 0 569  LYS A HD3  1 c 
ATOM   7213 H HE2  . LYS A 1 465 ? 18.249  51.408  -30.193 1.000 86.191 0 569  LYS A HE2  1 c 
ATOM   7214 H HE3  . LYS A 1 465 ? 18.424  51.853  -31.693 1.000 86.320 0 569  LYS A HE3  1 c 
ATOM   7215 H HZ1  . LYS A 1 465 ? 18.203  53.546  -29.557 1.000 90.941 0 569  LYS A HZ1  1 c 
ATOM   7216 H HZ2  . LYS A 1 465 ? 18.174  54.037  -30.950 1.000 90.941 0 569  LYS A HZ2  1 c 
ATOM   7217 H HZ3  . LYS A 1 465 ? 19.392  53.392  -30.419 1.000 90.941 0 569  LYS A HZ3  1 c 
ATOM   7218 N N    . ILE A 1 466 ? 14.842  46.811  -28.561 1.000 36.276 0 570  ILE A N    1 ? 
ATOM   7219 C CA   . ILE A 1 466 ? 13.871  45.722  -28.568 1.000 37.837 0 570  ILE A CA   1 ? 
ATOM   7220 C C    . ILE A 1 466 ? 12.459  46.312  -28.590 1.000 34.418 0 570  ILE A C    1 ? 
ATOM   7221 O O    . ILE A 1 466 ? 12.042  46.918  -27.604 1.000 33.682 0 570  ILE A O    1 ? 
ATOM   7222 C CB   . ILE A 1 466 ? 14.070  44.810  -27.336 1.000 37.144 0 570  ILE A CB   1 ? 
ATOM   7223 C CG1  . ILE A 1 466 ? 15.413  44.073  -27.392 1.000 43.703 0 570  ILE A CG1  1 ? 
ATOM   7224 C CG2  . ILE A 1 466 ? 12.924  43.817  -27.152 1.000 41.495 0 570  ILE A CG2  1 ? 
ATOM   7225 C CD1  . ILE A 1 466 ? 15.519  43.094  -28.543 1.000 44.680 0 570  ILE A CD1  1 ? 
ATOM   7226 H H    . ILE A 1 466 ? 15.255  47.029  -27.776 1.000 38.242 0 570  ILE A H    1 c 
ATOM   7227 H HA   . ILE A 1 466 ? 14.002  45.191  -29.375 1.000 36.796 0 570  ILE A HA   1 c 
ATOM   7228 H HB   . ILE A 1 466 ? 14.089  45.387  -26.547 1.000 39.222 0 570  ILE A HB   1 c 
ATOM   7229 H HG12 . ILE A 1 466 ? 16.132  44.732  -27.471 1.000 42.299 0 570  ILE A HG12 1 c 
ATOM   7230 H HG13 . ILE A 1 466 ? 15.541  43.588  -26.552 1.000 42.315 0 570  ILE A HG13 1 c 
ATOM   7231 H HG21 . ILE A 1 466 ? 13.209  43.096  -26.565 1.000 40.193 0 570  ILE A HG21 1 c 
ATOM   7232 H HG22 . ILE A 1 466 ? 12.669  43.449  -28.015 1.000 40.167 0 570  ILE A HG22 1 c 
ATOM   7233 H HG23 . ILE A 1 466 ? 12.160  44.269  -26.756 1.000 40.143 0 570  ILE A HG23 1 c 
ATOM   7234 H HD11 . ILE A 1 466 ? 14.745  42.501  -28.552 1.000 44.290 0 570  ILE A HD11 1 c 
ATOM   7235 H HD12 . ILE A 1 466 ? 16.329  42.561  -28.433 1.000 44.232 0 570  ILE A HD12 1 c 
ATOM   7236 H HD13 . ILE A 1 466 ? 15.566  43.579  -29.388 1.000 44.252 0 570  ILE A HD13 1 c 
ATOM   7237 N N    . ASN A 1 467 ? 11.668  46.019  -29.639 1.000 29.482 0 571  ASN A N    1 ? 
ATOM   7238 C CA   . ASN A 1 467 ? 10.275  46.471  -29.659 1.000 27.526 0 571  ASN A CA   1 ? 
ATOM   7239 C C    . ASN A 1 467 ? 9.400   45.550  -28.813 1.000 26.889 0 571  ASN A C    1 ? 
ATOM   7240 O O    . ASN A 1 467 ? 8.884   44.538  -29.302 1.000 23.579 0 571  ASN A O    1 ? 
ATOM   7241 C CB   . ASN A 1 467 ? 9.813   46.612  -31.108 1.000 24.516 0 571  ASN A CB   1 ? 
ATOM   7242 C CG   . ASN A 1 467 ? 8.418   47.194  -31.234 1.000 21.336 0 571  ASN A CG   1 ? 
ATOM   7243 O OD1  . ASN A 1 467 ? 7.627   47.155  -30.285 1.000 22.146 0 571  ASN A OD1  1 ? 
ATOM   7244 N ND2  . ASN A 1 467 ? 8.112   47.707  -32.422 1.000 24.476 0 571  ASN A ND2  1 ? 
ATOM   7245 H H    . ASN A 1 467 ? 11.994  45.537  -30.345 1.000 30.186 0 571  ASN A H    1 c 
ATOM   7246 H HA   . ASN A 1 467 ? 10.244  47.370  -29.260 1.000 27.236 0 571  ASN A HA   1 c 
ATOM   7247 H HB2  . ASN A 1 467 ? 10.442  47.188  -31.587 1.000 24.373 0 571  ASN A HB2  1 c 
ATOM   7248 H HB3  . ASN A 1 467 ? 9.830   45.732  -31.534 1.000 24.374 0 571  ASN A HB3  1 c 
ATOM   7249 H HD21 . ASN A 1 467 ? 8.677   47.627  -33.102 1.000 23.475 0 571  ASN A HD21 1 c 
ATOM   7250 H HD22 . ASN A 1 467 ? 7.339   48.129  -32.534 1.000 23.456 0 571  ASN A HD22 1 c 
ATOM   7251 N N    . SER A 1 468 ? 9.178   45.900  -27.542 1.000 24.060 0 572  SER A N    1 ? 
ATOM   7252 C CA   . SER A 1 468 ? 8.460   45.086  -26.581 1.000 24.889 0 572  SER A CA   1 ? 
ATOM   7253 C C    . SER A 1 468 ? 7.038   44.713  -27.020 1.000 26.590 0 572  SER A C    1 ? 
ATOM   7254 O O    . SER A 1 468 ? 6.667   43.539  -26.981 1.000 24.392 0 572  SER A O    1 ? 
ATOM   7255 C CB   . SER A 1 468 ? 8.500   45.725  -25.197 1.000 30.101 0 572  SER A CB   1 ? 
ATOM   7256 O OG   . SER A 1 468 ? 7.682   45.023  -24.279 1.000 37.443 0 572  SER A OG   1 ? 
ATOM   7257 H H    . SER A 1 468 ? 9.500   46.707  -27.260 1.000 25.001 0 572  SER A H    1 c 
ATOM   7258 H HA   . SER A 1 468 ? 8.962   44.234  -26.512 1.000 25.924 0 572  SER A HA   1 c 
ATOM   7259 H HB2  . SER A 1 468 ? 9.420   45.731  -24.872 1.000 30.381 0 572  SER A HB2  1 c 
ATOM   7260 H HB3  . SER A 1 468 ? 8.194   46.649  -25.261 1.000 30.351 0 572  SER A HB3  1 c 
ATOM   7261 H HG   . SER A 1 468 ? 7.731   45.395  -23.525 0.000 37.500 0 572  SER A HG   1 c 
ATOM   7262 N N    A SER A 1 469 ? 6.244   45.705  -27.451 0.500 22.638 0 573  SER A N    1 ? 
ATOM   7263 N N    B SER A 1 469 ? 6.235   45.719  -27.437 0.500 21.856 0 573  SER A N    1 ? 
ATOM   7264 C CA   A SER A 1 469 ? 4.857   45.449  -27.771 0.500 23.339 0 573  SER A CA   1 ? 
ATOM   7265 C CA   B SER A 1 469 ? 4.852   45.504  -27.829 0.500 22.344 0 573  SER A CA   1 ? 
ATOM   7266 C C    A SER A 1 469 ? 4.773   44.537  -28.996 0.500 20.636 0 573  SER A C    1 ? 
ATOM   7267 C C    B SER A 1 469 ? 4.805   44.509  -28.982 0.500 19.935 0 573  SER A C    1 ? 
ATOM   7268 O O    A SER A 1 469 ? 3.875   43.712  -29.015 0.500 21.643 0 573  SER A O    1 ? 
ATOM   7269 O O    B SER A 1 469 ? 3.950   43.642  -28.957 0.500 21.340 0 573  SER A O    1 ? 
ATOM   7270 C CB   A SER A 1 469 ? 4.107   46.747  -27.975 0.500 24.720 0 573  SER A CB   1 ? 
ATOM   7271 C CB   B SER A 1 469 ? 4.160   46.797  -28.264 0.500 21.560 0 573  SER A CB   1 ? 
ATOM   7272 O OG   A SER A 1 469 ? 4.182   47.531  -26.787 0.500 25.002 0 573  SER A OG   1 ? 
ATOM   7273 O OG   B SER A 1 469 ? 2.752   46.623  -28.425 0.500 22.890 0 573  SER A OG   1 ? 
ATOM   7274 H H    A SER A 1 469 ? 6.575   46.552  -27.543 0.500 23.696 0 573  SER A H    1 c 
ATOM   7275 H H    B SER A 1 469 ? 6.571   46.568  -27.473 0.500 23.036 0 573  SER A H    1 c 
ATOM   7276 H HA   A SER A 1 469 ? 4.448   44.972  -27.004 0.500 22.952 0 573  SER A HA   1 c 
ATOM   7277 H HA   B SER A 1 469 ? 4.361   45.121  -27.059 0.500 21.646 0 573  SER A HA   1 c 
ATOM   7278 H HB2  A SER A 1 469 ? 4.501   47.239  -28.720 0.500 24.468 0 573  SER A HB2  1 c 
ATOM   7279 H HB2  B SER A 1 469 ? 4.325   47.489  -27.595 0.500 22.046 0 573  SER A HB2  1 c 
ATOM   7280 H HB3  A SER A 1 469 ? 3.173   46.556  -28.185 0.500 24.468 0 573  SER A HB3  1 c 
ATOM   7281 H HB3  B SER A 1 469 ? 4.547   47.098  -29.107 0.500 22.046 0 573  SER A HB3  1 c 
ATOM   7282 H HG   A SER A 1 469 ? 3.748   48.247  -26.910 0.000 24.940 0 573  SER A HG   1 c 
ATOM   7283 H HG   B SER A 1 469 ? 2.420   47.366  -28.658 0.000 22.860 0 573  SER A HG   1 c 
ATOM   7284 N N    . ALA A 1 470 ? 5.666   44.719  -29.985 1.000 19.924 0 574  ALA A N    1 ? 
ATOM   7285 C CA   . ALA A 1 470 ? 5.608   43.909  -31.216 1.000 17.861 0 574  ALA A CA   1 ? 
ATOM   7286 C C    . ALA A 1 470 ? 5.949   42.452  -30.858 1.000 21.584 0 574  ALA A C    1 ? 
ATOM   7287 O O    . ALA A 1 470 ? 5.325   41.517  -31.373 1.000 18.314 0 574  ALA A O    1 ? 
ATOM   7288 C CB   . ALA A 1 470 ? 6.501   44.439  -32.326 1.000 18.751 0 574  ALA A CB   1 ? 
ATOM   7289 H H    . ALA A 1 470 ? 6.307   45.366  -29.907 1.000 19.726 0 574  ALA A H    1 c 
ATOM   7290 H HA   . ALA A 1 470 ? 4.666   43.925  -31.542 1.000 19.089 0 574  ALA A HA   1 c 
ATOM   7291 H HB1  . ALA A 1 470 ? 6.232   45.343  -32.559 1.000 18.484 0 574  ALA A HB1  1 c 
ATOM   7292 H HB2  . ALA A 1 470 ? 7.426   44.447  -32.026 1.000 18.484 0 574  ALA A HB2  1 c 
ATOM   7293 H HB3  . ALA A 1 470 ? 6.423   43.869  -33.109 1.000 18.484 0 574  ALA A HB3  1 c 
ATOM   7294 N N    . ILE A 1 471 ? 6.966   42.270  -30.009 1.000 22.994 0 575  ILE A N    1 ? 
ATOM   7295 C CA   . ILE A 1 471 ? 7.344   40.932  -29.513 1.000 22.188 0 575  ILE A CA   1 ? 
ATOM   7296 C C    . ILE A 1 471 ? 6.204   40.244  -28.790 1.000 22.103 0 575  ILE A C    1 ? 
ATOM   7297 O O    . ILE A 1 471 ? 5.922   39.050  -29.054 1.000 20.652 0 575  ILE A O    1 ? 
ATOM   7298 C CB   . ILE A 1 471 ? 8.584   41.011  -28.602 1.000 25.612 0 575  ILE A CB   1 ? 
ATOM   7299 C CG1  . ILE A 1 471 ? 9.793   41.494  -29.330 1.000 30.299 0 575  ILE A CG1  1 ? 
ATOM   7300 C CG2  . ILE A 1 471 ? 8.821   39.648  -27.940 1.000 25.766 0 575  ILE A CG2  1 ? 
ATOM   7301 C CD1  . ILE A 1 471 ? 10.443  40.498  -30.253 1.000 39.463 0 575  ILE A CD1  1 ? 
ATOM   7302 H H    . ILE A 1 471 ? 7.443   42.995  -29.723 1.000 22.534 0 575  ILE A H    1 c 
ATOM   7303 H HA   . ILE A 1 471 ? 7.579   40.386  -30.288 1.000 23.031 0 575  ILE A HA   1 c 
ATOM   7304 H HB   . ILE A 1 471 ? 8.390   41.656  -27.893 1.000 25.786 0 575  ILE A HB   1 c 
ATOM   7305 H HG12 . ILE A 1 471 ? 9.546   42.281  -29.855 1.000 30.803 0 575  ILE A HG12 1 c 
ATOM   7306 H HG13 . ILE A 1 471 ? 10.457  41.780  -28.669 1.000 30.938 0 575  ILE A HG13 1 c 
ATOM   7307 H HG21 . ILE A 1 471 ? 9.730   39.606  -27.599 1.000 25.856 0 575  ILE A HG21 1 c 
ATOM   7308 H HG22 . ILE A 1 471 ? 8.690   38.940  -28.593 1.000 25.761 0 575  ILE A HG22 1 c 
ATOM   7309 H HG23 . ILE A 1 471 ? 8.197   39.528  -27.204 1.000 25.735 0 575  ILE A HG23 1 c 
ATOM   7310 H HD11 . ILE A 1 471 ? 10.708  39.700  -29.759 1.000 36.253 0 575  ILE A HD11 1 c 
ATOM   7311 H HD12 . ILE A 1 471 ? 11.233  40.904  -30.658 1.000 36.360 0 575  ILE A HD12 1 c 
ATOM   7312 H HD13 . ILE A 1 471 ? 9.813   40.251  -30.956 1.000 36.130 0 575  ILE A HD13 1 c 
ATOM   7313 N N    . LYS A 1 472 ? 5.529   40.934  -27.841 1.000 20.457 0 576  LYS A N    1 ? 
ATOM   7314 C CA   . LYS A 1 472 ? 4.361   40.434  -27.168 1.000 22.646 0 576  LYS A CA   1 ? 
ATOM   7315 C C    . LYS A 1 472 ? 3.335   39.980  -28.171 1.000 21.152 0 576  LYS A C    1 ? 
ATOM   7316 O O    . LYS A 1 472 ? 2.798   38.900  -28.052 1.000 22.633 0 576  LYS A O    1 ? 
ATOM   7317 C CB   . LYS A 1 472 ? 3.722   41.388  -26.153 1.000 26.214 0 576  LYS A CB   1 ? 
ATOM   7318 C CG   . LYS A 1 472 ? 4.778   41.752  -25.132 1.000 37.227 0 576  LYS A CG   1 ? 
ATOM   7319 C CD   . LYS A 1 472 ? 4.285   42.640  -23.991 1.000 44.970 0 576  LYS A CD   1 ? 
ATOM   7320 C CE   . LYS A 1 472 ? 5.349   42.770  -22.970 1.000 56.987 0 576  LYS A CE   1 ? 
ATOM   7321 N NZ   . LYS A 1 472 ? 4.925   43.637  -21.863 1.000 67.254 0 576  LYS A NZ   1 ? 
ATOM   7322 H H    . LYS A 1 472 ? 5.826   41.772  -27.627 1.000 21.549 0 576  LYS A H    1 c 
ATOM   7323 H HA   . LYS A 1 472 ? 4.642   39.634  -26.656 1.000 22.585 0 576  LYS A HA   1 c 
ATOM   7324 H HB2  . LYS A 1 472 ? 3.403   42.200  -26.602 1.000 27.514 0 576  LYS A HB2  1 c 
ATOM   7325 H HB3  . LYS A 1 472 ? 2.965   40.953  -25.705 1.000 27.514 0 576  LYS A HB3  1 c 
ATOM   7326 H HG2  . LYS A 1 472 ? 5.140   40.924  -24.753 1.000 35.510 0 576  LYS A HG2  1 c 
ATOM   7327 H HG3  . LYS A 1 472 ? 5.511   42.210  -25.589 1.000 35.415 0 576  LYS A HG3  1 c 
ATOM   7328 H HD2  . LYS A 1 472 ? 4.054   43.529  -24.339 1.000 45.567 0 576  LYS A HD2  1 c 
ATOM   7329 H HD3  . LYS A 1 472 ? 3.486   42.241  -23.582 1.000 45.568 0 576  LYS A HD3  1 c 
ATOM   7330 H HE2  . LYS A 1 472 ? 5.570   41.890  -22.616 1.000 55.893 0 576  LYS A HE2  1 c 
ATOM   7331 H HE3  . LYS A 1 472 ? 6.150   43.142  -23.378 1.000 55.926 0 576  LYS A HE3  1 c 
ATOM   7332 H HZ1  . LYS A 1 472 ? 4.196   43.282  -21.458 1.000 63.908 0 576  LYS A HZ1  1 c 
ATOM   7333 H HZ2  . LYS A 1 472 ? 4.717   44.460  -22.181 1.000 63.908 0 576  LYS A HZ2  1 c 
ATOM   7334 H HZ3  . LYS A 1 472 ? 5.595   43.712  -21.259 1.000 63.908 0 576  LYS A HZ3  1 c 
ATOM   7335 N N    . LEU A 1 473 ? 3.039   40.815  -29.180 1.000 19.776 0 577  LEU A N    1 ? 
ATOM   7336 C CA   . LEU A 1 473 ? 2.000   40.441  -30.121 1.000 19.563 0 577  LEU A CA   1 ? 
ATOM   7337 C C    . LEU A 1 473 ? 2.393   39.159  -30.878 1.000 18.940 0 577  LEU A C    1 ? 
ATOM   7338 O O    . LEU A 1 473 ? 1.537   38.353  -31.194 1.000 20.700 0 577  LEU A O    1 ? 
ATOM   7339 C CB   . LEU A 1 473 ? 1.780   41.587  -31.106 1.000 19.466 0 577  LEU A CB   1 ? 
ATOM   7340 C CG   . LEU A 1 473 ? 1.087   42.824  -30.513 1.000 22.667 0 577  LEU A CG   1 ? 
ATOM   7341 C CD1  . LEU A 1 473 ? 1.158   43.968  -31.523 1.000 22.547 0 577  LEU A CD1  1 ? 
ATOM   7342 C CD2  . LEU A 1 473 ? -0.340  42.608  -30.125 1.000 28.490 0 577  LEU A CD2  1 ? 
ATOM   7343 H H    . LEU A 1 473 ? 3.478   41.611  -29.276 1.000 20.063 0 577  LEU A H    1 c 
ATOM   7344 H HA   . LEU A 1 473 ? 1.164   40.273  -29.617 1.000 19.572 0 577  LEU A HA   1 c 
ATOM   7345 H HB2  . LEU A 1 473 ? 2.656   41.860  -31.464 1.000 20.186 0 577  LEU A HB2  1 c 
ATOM   7346 H HB3  . LEU A 1 473 ? 1.234   41.252  -31.854 1.000 20.167 0 577  LEU A HB3  1 c 
ATOM   7347 H HG   . LEU A 1 473 ? 1.583   43.098  -29.701 1.000 22.991 0 577  LEU A HG   1 c 
ATOM   7348 H HD11 . LEU A 1 473 ? 2.088   44.171  -31.720 1.000 22.571 0 577  LEU A HD11 1 c 
ATOM   7349 H HD12 . LEU A 1 473 ? 0.727   44.757  -31.151 1.000 22.604 0 577  LEU A HD12 1 c 
ATOM   7350 H HD13 . LEU A 1 473 ? 0.704   43.708  -32.342 1.000 22.584 0 577  LEU A HD13 1 c 
ATOM   7351 H HD21 . LEU A 1 473 ? -0.390  41.930  -29.431 1.000 26.594 0 577  LEU A HD21 1 c 
ATOM   7352 H HD22 . LEU A 1 473 ? -0.846  42.315  -30.900 1.000 26.699 0 577  LEU A HD22 1 c 
ATOM   7353 H HD23 . LEU A 1 473 ? -0.715  43.440  -29.790 1.000 26.589 0 577  LEU A HD23 1 c 
ATOM   7354 N N    . GLN A 1 474 ? 3.661   39.040  -31.221 1.000 17.620 0 578  GLN A N    1 ? 
ATOM   7355 C CA   . GLN A 1 474 ? 4.113   37.902  -32.027 1.000 16.643 0 578  GLN A CA   1 ? 
ATOM   7356 C C    . GLN A 1 474 ? 4.106   36.608  -31.212 1.000 19.268 0 578  GLN A C    1 ? 
ATOM   7357 O O    . GLN A 1 474 ? 3.856   35.531  -31.779 1.000 20.209 0 578  GLN A O    1 ? 
ATOM   7358 C CB   . GLN A 1 474 ? 5.437   38.249  -32.676 1.000 17.936 0 578  GLN A CB   1 ? 
ATOM   7359 C CG   . GLN A 1 474 ? 6.008   37.161  -33.591 1.000 18.342 0 578  GLN A CG   1 ? 
ATOM   7360 C CD   . GLN A 1 474 ? 5.101   36.814  -34.767 1.000 18.522 0 578  GLN A CD   1 ? 
ATOM   7361 O OE1  . GLN A 1 474 ? 4.193   37.576  -35.158 1.000 18.478 0 578  GLN A OE1  1 ? 
ATOM   7362 N NE2  . GLN A 1 474 ? 5.397   35.674  -35.386 1.000 16.812 0 578  GLN A NE2  1 ? 
ATOM   7363 H H    . GLN A 1 474 ? 4.268   39.671  -30.961 1.000 17.728 0 578  GLN A H    1 c 
ATOM   7364 H HA   . GLN A 1 474 ? 3.460   37.786  -32.762 1.000 17.564 0 578  GLN A HA   1 c 
ATOM   7365 H HB2  . GLN A 1 474 ? 5.320   39.070  -33.198 1.000 17.731 0 578  GLN A HB2  1 c 
ATOM   7366 H HB3  . GLN A 1 474 ? 6.087   38.440  -31.969 1.000 17.764 0 578  GLN A HB3  1 c 
ATOM   7367 H HG2  . GLN A 1 474 ? 6.874   37.460  -33.942 1.000 18.290 0 578  GLN A HG2  1 c 
ATOM   7368 H HG3  . GLN A 1 474 ? 6.167   36.348  -33.066 1.000 18.288 0 578  GLN A HG3  1 c 
ATOM   7369 H HE21 . GLN A 1 474 ? 6.132   35.228  -35.170 1.000 17.333 0 578  GLN A HE21 1 c 
ATOM   7370 H HE22 . GLN A 1 474 ? 4.858   35.363  -36.017 1.000 17.332 0 578  GLN A HE22 1 c 
ATOM   7371 N N    . LEU A 1 475 ? 4.455   36.701  -29.928 1.000 18.865 0 579  LEU A N    1 ? 
ATOM   7372 C CA   . LEU A 1 475 ? 4.546   35.506  -29.093 1.000 17.558 0 579  LEU A CA   1 ? 
ATOM   7373 C C    . LEU A 1 475 ? 3.174   34.986  -28.733 1.000 18.686 0 579  LEU A C    1 ? 
ATOM   7374 O O    . LEU A 1 475 ? 3.037   33.784  -28.468 1.000 18.694 0 579  LEU A O    1 ? 
ATOM   7375 C CB   . LEU A 1 475 ? 5.386   35.727  -27.841 1.000 18.404 0 579  LEU A CB   1 ? 
ATOM   7376 C CG   . LEU A 1 475 ? 5.749   34.456  -27.063 1.000 18.989 0 579  LEU A CG   1 ? 
ATOM   7377 C CD1  . LEU A 1 475 ? 6.816   33.665  -27.809 1.000 20.313 0 579  LEU A CD1  1 ? 
ATOM   7378 C CD2  . LEU A 1 475 ? 6.218   34.803  -25.658 1.000 20.595 0 579  LEU A CD2  1 ? 
ATOM   7379 H H    . LEU A 1 475 ? 4.646   37.515  -29.561 1.000 18.635 0 579  LEU A H    1 c 
ATOM   7380 H HA   . LEU A 1 475 ? 4.987   34.806  -29.637 1.000 18.205 0 579  LEU A HA   1 c 
ATOM   7381 H HB2  . LEU A 1 475 ? 6.219   36.181  -28.105 1.000 18.412 0 579  LEU A HB2  1 c 
ATOM   7382 H HB3  . LEU A 1 475 ? 4.890   36.330  -27.240 1.000 18.374 0 579  LEU A HB3  1 c 
ATOM   7383 H HG   . LEU A 1 475 ? 4.940   33.890  -26.985 1.000 19.403 0 579  LEU A HG   1 c 
ATOM   7384 H HD11 . LEU A 1 475 ? 6.461   33.362  -28.662 1.000 19.886 0 579  LEU A HD11 1 c 
ATOM   7385 H HD12 . LEU A 1 475 ? 7.080   32.895  -27.278 1.000 19.896 0 579  LEU A HD12 1 c 
ATOM   7386 H HD13 . LEU A 1 475 ? 7.591   34.230  -27.965 1.000 19.849 0 579  LEU A HD13 1 c 
ATOM   7387 H HD21 . LEU A 1 475 ? 5.506   35.265  -25.183 1.000 20.095 0 579  LEU A HD21 1 c 
ATOM   7388 H HD22 . LEU A 1 475 ? 6.999   35.379  -25.709 1.000 20.105 0 579  LEU A HD22 1 c 
ATOM   7389 H HD23 . LEU A 1 475 ? 6.448   33.988  -25.182 1.000 20.105 0 579  LEU A HD23 1 c 
ATOM   7390 N N    . THR A 1 476 ? 2.155   35.856  -28.599 1.000 20.008 0 580  THR A N    1 ? 
ATOM   7391 C CA   . THR A 1 476 ? 0.879   35.449  -28.033 1.000 20.805 0 580  THR A CA   1 ? 
ATOM   7392 C C    . THR A 1 476 ? -0.211  35.388  -29.088 1.000 24.224 0 580  THR A C    1 ? 
ATOM   7393 O O    . THR A 1 476 ? -1.321  34.962  -28.781 1.000 29.270 0 580  THR A O    1 ? 
ATOM   7394 C CB   . THR A 1 476 ? 0.449   36.386  -26.901 1.000 24.119 0 580  THR A CB   1 ? 
ATOM   7395 O OG1  . THR A 1 476 ? 0.162   37.675  -27.434 1.000 26.645 0 580  THR A OG1  1 ? 
ATOM   7396 C CG2  . THR A 1 476 ? 1.544   36.641  -25.885 1.000 26.103 0 580  THR A CG2  1 ? 
ATOM   7397 H H    . THR A 1 476 ? 2.274   36.731  -28.836 1.000 19.942 0 580  THR A H    1 c 
ATOM   7398 H HA   . THR A 1 476 ? 0.986   34.550  -27.654 1.000 21.783 0 580  THR A HA   1 c 
ATOM   7399 H HB   . THR A 1 476 ? -0.351  36.028  -26.448 1.000 24.376 0 580  THR A HB   1 c 
ATOM   7400 H HG1  . THR A 1 476 ? 0.864   37.995  -27.822 0.000 26.530 0 580  THR A HG1  1 c 
ATOM   7401 H HG21 . THR A 1 476 ? 1.207   37.227  -25.186 1.000 25.478 0 580  THR A HG21 1 c 
ATOM   7402 H HG22 . THR A 1 476 ? 2.303   37.064  -26.321 1.000 25.444 0 580  THR A HG22 1 c 
ATOM   7403 H HG23 . THR A 1 476 ? 1.826   35.798  -25.492 1.000 25.484 0 580  THR A HG23 1 c 
ATOM   7404 N N    . ALA A 1 477 ? 0.145   35.923  -30.248 1.000 26.731 0 581  ALA A N    1 ? 
ATOM   7405 C CA   . ALA A 1 477 ? -0.654  36.057  -31.437 1.000 35.179 0 581  ALA A CA   1 ? 
ATOM   7406 C C    . ALA A 1 477 ? -1.868  36.912  -31.077 1.000 41.049 0 581  ALA A C    1 ? 
ATOM   7407 O O    . ALA A 1 477 ? -2.983  36.670  -31.546 1.000 42.512 0 581  ALA A O    1 ? 
ATOM   7408 C CB   . ALA A 1 477 ? -0.925  34.673  -32.018 1.000 38.364 0 581  ALA A CB   1 ? 
ATOM   7409 H H    . ALA A 1 477 ? 0.998   36.242  -30.303 1.000 27.608 0 581  ALA A H    1 c 
ATOM   7410 H HA   . ALA A 1 477 ? -0.117  36.570  -32.102 1.000 34.741 0 581  ALA A HA   1 c 
ATOM   7411 H HB1  . ALA A 1 477 ? -0.086  34.197  -32.137 1.000 37.371 0 581  ALA A HB1  1 c 
ATOM   7412 H HB2  . ALA A 1 477 ? -1.497  34.171  -31.413 1.000 37.282 0 581  ALA A HB2  1 c 
ATOM   7413 H HB3  . ALA A 1 477 ? -1.369  34.762  -32.876 1.000 37.370 0 581  ALA A HB3  1 c 
ATOM   7414 N N    . GLN A 1 478 ? -1.604  37.935  -30.233 1.000 43.276 0 582  GLN A N    1 ? 
ATOM   7415 C CA   . GLN A 1 478 ? -2.612  38.885  -29.789 1.000 40.830 0 582  GLN A CA   1 ? 
ATOM   7416 C C    . GLN A 1 478 ? -2.880  39.716  -31.027 1.000 41.565 0 582  GLN A C    1 ? 
ATOM   7417 O O    . GLN A 1 478 ? -1.961  40.110  -31.741 1.000 53.663 0 582  GLN A O    1 ? 
ATOM   7418 C CB   . GLN A 1 478 ? -2.240  39.676  -28.516 1.000 38.839 0 582  GLN A CB   1 ? 
ATOM   7419 C CG   . GLN A 1 478 ? -3.131  40.885  -28.216 1.000 39.218 0 582  GLN A CG   1 ? 
ATOM   7420 C CD   . GLN A 1 478 ? -2.699  41.727  -27.027 1.000 41.510 0 582  GLN A CD   1 ? 
ATOM   7421 O OE1  . GLN A 1 478 ? -2.231  41.222  -25.997 1.000 45.431 0 582  GLN A OE1  1 ? 
ATOM   7422 N NE2  . GLN A 1 478 ? -2.849  43.039  -27.142 1.000 37.218 0 582  GLN A NE2  1 ? 
ATOM   7423 H H    . GLN A 1 478 ? -0.747  38.049  -29.935 1.000 41.837 0 582  GLN A H    1 c 
ATOM   7424 H HA   . GLN A 1 478 ? -3.434  38.373  -29.580 1.000 41.008 0 582  GLN A HA   1 c 
ATOM   7425 H HB2  . GLN A 1 478 ? -2.276  39.063  -27.752 1.000 39.346 0 582  GLN A HB2  1 c 
ATOM   7426 H HB3  . GLN A 1 478 ? -1.314  39.982  -28.602 1.000 39.257 0 582  GLN A HB3  1 c 
ATOM   7427 H HG2  . GLN A 1 478 ? -3.156  41.465  -29.007 1.000 39.583 0 582  GLN A HG2  1 c 
ATOM   7428 H HG3  . GLN A 1 478 ? -4.046  40.572  -28.053 1.000 39.634 0 582  GLN A HG3  1 c 
ATOM   7429 H HE21 . GLN A 1 478 ? -3.355  43.376  -27.790 1.000 38.516 0 582  GLN A HE21 1 c 
ATOM   7430 H HE22 . GLN A 1 478 ? -2.444  43.581  -26.568 1.000 38.542 0 582  GLN A HE22 1 c 
ATOM   7431 N N    . SER A 1 479 ? -4.148  39.862  -31.362 1.000 36.034 0 583  SER A N    1 ? 
ATOM   7432 C CA   . SER A 1 479 ? -4.498  40.345  -32.693 1.000 39.727 0 583  SER A CA   1 ? 
ATOM   7433 C C    . SER A 1 479 ? -4.408  41.873  -32.661 1.000 36.863 0 583  SER A C    1 ? 
ATOM   7434 O O    . SER A 1 479 ? -3.862  42.501  -33.576 1.000 34.108 0 583  SER A O    1 ? 
ATOM   7435 C CB   . SER A 1 479 ? -5.886  39.883  -33.085 1.000 36.388 0 583  SER A CB   1 ? 
ATOM   7436 O OG   . SER A 1 479 ? -6.001  38.468  -33.238 1.000 51.234 0 583  SER A OG   1 ? 
ATOM   7437 H H    . SER A 1 479 ? -4.812  39.660  -30.767 1.000 38.074 0 583  SER A H    1 c 
ATOM   7438 H HA   . SER A 1 479 ? -3.842  39.996  -33.349 1.000 37.941 0 583  SER A HA   1 c 
ATOM   7439 H HB2  . SER A 1 479 ? -6.517  40.177  -32.401 1.000 40.282 0 583  SER A HB2  1 c 
ATOM   7440 H HB3  . SER A 1 479 ? -6.140  40.314  -33.915 1.000 40.267 0 583  SER A HB3  1 c 
ATOM   7441 H HG   . SER A 1 479 ? -6.789  38.282  -33.471 0.000 51.470 0 583  SER A HG   1 c 
ATOM   7442 N N    . GLN A 1 480 ? -4.834  42.438  -31.520 1.000 29.616 0 584  GLN A N    1 ? 
ATOM   7443 C CA   . GLN A 1 480 ? -5.226  43.840  -31.451 1.000 28.896 0 584  GLN A CA   1 ? 
ATOM   7444 C C    . GLN A 1 480 ? -4.619  44.529  -30.245 1.000 32.824 0 584  GLN A C    1 ? 
ATOM   7445 O O    . GLN A 1 480 ? -4.349  43.871  -29.247 1.000 30.761 0 584  GLN A O    1 ? 
ATOM   7446 C CB   . GLN A 1 480 ? -6.733  43.931  -31.338 1.000 26.516 0 584  GLN A CB   1 ? 
ATOM   7447 C CG   . GLN A 1 480 ? -7.435  43.629  -32.657 1.000 34.610 0 584  GLN A CG   1 ? 
ATOM   7448 C CD   . GLN A 1 480 ? -8.867  43.208  -32.473 1.000 36.680 0 584  GLN A CD   1 ? 
ATOM   7449 O OE1  . GLN A 1 480 ? -9.824  43.839  -32.949 1.000 32.451 0 584  GLN A OE1  1 ? 
ATOM   7450 N NE2  . GLN A 1 480 ? -9.021  42.124  -31.734 1.000 40.779 0 584  GLN A NE2  1 ? 
ATOM   7451 H H    . GLN A 1 480 ? -4.881  41.936  -30.758 1.000 31.177 0 584  GLN A H    1 c 
ATOM   7452 H HA   . GLN A 1 480 ? -4.924  44.298  -32.274 1.000 29.317 0 584  GLN A HA   1 c 
ATOM   7453 H HB2  . GLN A 1 480 ? -7.038  43.299  -30.655 1.000 28.891 0 584  GLN A HB2  1 c 
ATOM   7454 H HB3  . GLN A 1 480 ? -6.978  44.833  -31.044 1.000 28.787 0 584  GLN A HB3  1 c 
ATOM   7455 H HG2  . GLN A 1 480 ? -7.413  44.429  -33.222 1.000 33.010 0 584  GLN A HG2  1 c 
ATOM   7456 H HG3  . GLN A 1 480 ? -6.953  42.916  -33.127 1.000 32.994 0 584  GLN A HG3  1 c 
ATOM   7457 H HE21 . GLN A 1 480 ? -8.346  41.559  -31.625 1.000 39.235 0 584  GLN A HE21 1 c 
ATOM   7458 H HE22 . GLN A 1 480 ? -9.804  41.960  -31.351 1.000 39.360 0 584  GLN A HE22 1 c 
ATOM   7459 N N    . VAL A 1 481 ? -4.429  45.852  -30.362 1.000 27.568 0 585  VAL A N    1 ? 
ATOM   7460 C CA   . VAL A 1 481 ? -3.935  46.671  -29.254 1.000 26.918 0 585  VAL A CA   1 ? 
ATOM   7461 C C    . VAL A 1 481 ? -5.017  47.659  -28.810 1.000 29.718 0 585  VAL A C    1 ? 
ATOM   7462 O O    . VAL A 1 481 ? -5.925  47.961  -29.587 1.000 35.831 0 585  VAL A O    1 ? 
ATOM   7463 C CB   . VAL A 1 481 ? -2.620  47.375  -29.604 1.000 28.965 0 585  VAL A CB   1 ? 
ATOM   7464 C CG1  . VAL A 1 481 ? -1.524  46.328  -29.742 1.000 32.700 0 585  VAL A CG1  1 ? 
ATOM   7465 C CG2  . VAL A 1 481 ? -2.716  48.276  -30.828 1.000 27.110 0 585  VAL A CG2  1 ? 
ATOM   7466 H H    . VAL A 1 481 ? -4.622  46.260  -31.157 1.000 28.582 0 585  VAL A H    1 c 
ATOM   7467 H HA   . VAL A 1 481 ? -3.756  46.075  -28.501 1.000 28.004 0 585  VAL A HA   1 c 
ATOM   7468 H HB   . VAL A 1 481 ? -2.385  47.946  -28.837 1.000 28.919 0 585  VAL A HB   1 c 
ATOM   7469 H HG11 . VAL A 1 481 ? -1.751  45.711  -30.458 1.000 31.522 0 585  VAL A HG11 1 c 
ATOM   7470 H HG12 . VAL A 1 481 ? -1.436  45.836  -28.908 1.000 31.519 0 585  VAL A HG12 1 c 
ATOM   7471 H HG13 . VAL A 1 481 ? -0.681  46.765  -29.949 1.000 31.539 0 585  VAL A HG13 1 c 
ATOM   7472 H HG21 . VAL A 1 481 ? -1.870  48.736  -30.958 1.000 27.648 0 585  VAL A HG21 1 c 
ATOM   7473 H HG22 . VAL A 1 481 ? -3.422  48.931  -30.698 1.000 27.656 0 585  VAL A HG22 1 c 
ATOM   7474 H HG23 . VAL A 1 481 ? -2.915  47.739  -31.613 1.000 27.653 0 585  VAL A HG23 1 c 
ATOM   7475 N N    . GLN A 1 482 ? -4.806  48.220  -27.602 1.000 31.534 0 586  GLN A N    1 ? 
ATOM   7476 C CA   . GLN A 1 482 ? -5.846  48.810  -26.764 1.000 45.862 0 586  GLN A CA   1 ? 
ATOM   7477 C C    . GLN A 1 482 ? -6.511  49.927  -27.555 1.000 47.397 0 586  GLN A C    1 ? 
ATOM   7478 O O    . GLN A 1 482 ? -5.807  50.704  -28.199 1.000 49.121 0 586  GLN A O    1 ? 
ATOM   7479 C CB   . GLN A 1 482 ? -5.302  49.362  -25.441 1.000 45.925 0 586  GLN A CB   1 ? 
ATOM   7480 H H    . GLN A 1 482 ? -3.950  48.229  -27.281 1.000 33.820 0 586  GLN A H    1 c 
ATOM   7481 H HA   . GLN A 1 482 ? -6.520  48.111  -26.567 1.000 42.983 0 586  GLN A HA   1 c 
ATOM   7482 H HB2  . GLN A 1 482 ? -4.661  50.077  -25.639 1.000 45.906 0 586  GLN A HB2  1 c 
ATOM   7483 H HB3  . GLN A 1 482 ? -6.037  49.772  -24.942 0.000 45.830 0 586  GLN A HB3  1 c 
ATOM   7484 N N    . MET A 1 483 ? -7.854  49.966  -27.475 1.000 53.772 0 587  MET A N    1 ? 
ATOM   7485 C CA   . MET A 1 483 ? -8.711  50.757  -28.350 1.000 54.149 0 587  MET A CA   1 ? 
ATOM   7486 C C    . MET A 1 483 ? -8.392  52.239  -28.170 1.000 40.845 0 587  MET A C    1 ? 
ATOM   7487 O O    . MET A 1 483 ? -7.778  52.829  -29.037 1.000 50.362 0 587  MET A O    1 ? 
ATOM   7488 C CB   . MET A 1 483 ? -10.197 50.464  -28.079 1.000 53.125 0 587  MET A CB   1 ? 
ATOM   7489 H H    . MET A 1 483 ? -8.257  49.465  -26.825 1.000 52.141 0 587  MET A H    1 c 
ATOM   7490 H HA   . MET A 1 483 ? -8.500  50.509  -29.286 1.000 51.142 0 587  MET A HA   1 c 
ATOM   7491 H HB2  . MET A 1 483 ? -10.339 50.428  -27.109 1.000 53.321 0 587  MET A HB2  1 c 
ATOM   7492 H HB3  . MET A 1 483 ? -10.744 51.030  -28.655 0.000 51.840 0 587  MET A HB3  1 c 
ATOM   7493 N N    . LYS A 1 484 ? -8.740  52.797  -27.018 1.000 43.621 0 588  LYS A N    1 ? 
ATOM   7494 C CA   . LYS A 1 484 ? -8.543  54.208  -26.704 1.000 55.871 0 588  LYS A CA   1 ? 
ATOM   7495 C C    . LYS A 1 484 ? -7.041  54.576  -26.682 1.000 58.108 0 588  LYS A C    1 ? 
ATOM   7496 O O    . LYS A 1 484 ? -6.235  53.784  -26.122 1.000 60.370 0 588  LYS A O    1 ? 
ATOM   7497 C CB   . LYS A 1 484 ? -9.202  54.556  -25.358 1.000 53.644 0 588  LYS A CB   1 ? 
ATOM   7498 H H    . LYS A 1 484 ? -9.119  52.266  -26.378 1.000 45.632 0 588  LYS A H    1 c 
ATOM   7499 H HA   . LYS A 1 484 ? -8.983  54.743  -27.411 1.000 53.197 0 588  LYS A HA   1 c 
ATOM   7500 H HB2  . LYS A 1 484 ? -8.769  54.030  -24.652 1.000 54.286 0 588  LYS A HB2  1 c 
ATOM   7501 H HB3  . LYS A 1 484 ? -9.021  55.501  -25.169 0.000 54.070 0 588  LYS A HB3  1 c 
HETATM 7502 C C1   . K5O B 2 .   ? 15.388  8.864   -10.960 1.000 15.108 0 601  K5O A C1   1 ? 
HETATM 7503 N N1   . K5O B 2 .   ? 14.393  7.979   -11.539 1.000 14.390 0 601  K5O A N1   1 ? 
HETATM 7504 C C2   . K5O B 2 .   ? 13.141  8.369   -11.859 1.000 13.443 0 601  K5O A C2   1 ? 
HETATM 7505 N N2   . K5O B 2 .   ? 12.863  9.670   -11.683 1.000 14.696 0 601  K5O A N2   1 ? 
HETATM 7506 C C3   . K5O B 2 .   ? 11.650  10.148  -12.046 1.000 14.843 0 601  K5O A C3   1 ? 
HETATM 7507 N N3   . K5O B 2 .   ? 11.357  11.489  -11.946 1.000 15.700 0 601  K5O A N3   1 ? 
HETATM 7508 C C4   . K5O B 2 .   ? 12.377  12.453  -11.553 1.000 15.350 0 601  K5O A C4   1 ? 
HETATM 7509 C C5   . K5O B 2 .   ? 12.072  12.932  -10.156 1.000 16.392 0 601  K5O A C5   1 ? 
HETATM 7510 C C6   . K5O B 2 .   ? 13.031  14.053  -9.784  1.000 16.710 0 601  K5O A C6   1 ? 
HETATM 7511 N N4   . K5O B 2 .   ? 12.979  15.164  -10.735 1.000 15.830 0 601  K5O A N4   1 ? 
HETATM 7512 C C7   . K5O B 2 .   ? 13.968  16.179  -10.284 1.000 17.003 0 601  K5O A C7   1 ? 
HETATM 7513 C C8   . K5O B 2 .   ? 14.050  17.405  -11.138 1.000 17.222 0 601  K5O A C8   1 ? 
HETATM 7514 C C9   . K5O B 2 .   ? 12.962  18.286  -11.151 1.000 18.287 0 601  K5O A C9   1 ? 
HETATM 7515 C C10  . K5O B 2 .   ? 12.981  19.460  -11.889 1.000 18.719 0 601  K5O A C10  1 ? 
HETATM 7516 C C11  . K5O B 2 .   ? 14.148  19.764  -12.588 1.000 16.151 0 601  K5O A C11  1 ? 
HETATM 7517 N N5   . K5O B 2 .   ? 14.483  20.881  -13.387 1.000 16.033 0 601  K5O A N5   1 ? 
HETATM 7518 C C12  . K5O B 2 .   ? 13.634  22.056  -13.591 1.000 17.993 0 601  K5O A C12  1 ? 
HETATM 7519 C C13  . K5O B 2 .   ? 13.528  22.898  -12.318 1.000 19.052 0 601  K5O A C13  1 ? 
HETATM 7520 C C14  . K5O B 2 .   ? 12.693  24.144  -12.598 1.000 21.542 0 601  K5O A C14  1 ? 
HETATM 7521 N N6   . K5O B 2 .   ? 14.717  23.337  -11.551 1.000 22.898 0 601  K5O A N6   1 ? 
HETATM 7522 C C15  . K5O B 2 .   ? 15.329  22.345  -10.687 1.000 26.348 0 601  K5O A C15  1 ? 
HETATM 7523 C C16  . K5O B 2 .   ? 16.314  22.966  -9.742  1.000 26.976 0 601  K5O A C16  1 ? 
HETATM 7524 N N7   . K5O B 2 .   ? 17.315  23.698  -10.532 1.000 25.587 0 601  K5O A N7   1 ? 
HETATM 7525 C C17  . K5O B 2 .   ? 16.756  24.713  -11.433 1.000 26.042 0 601  K5O A C17  1 ? 
HETATM 7526 C C18  . K5O B 2 .   ? 15.700  24.098  -12.309 1.000 22.365 0 601  K5O A C18  1 ? 
HETATM 7527 S S1   . K5O B 2 .   ? 18.672  24.129  -9.707  1.000 29.459 0 601  K5O A S1   1 ? 
HETATM 7528 C C19  . K5O B 2 .   ? 18.190  25.168  -8.387  1.000 33.479 0 601  K5O A C19  1 ? 
HETATM 7529 O O1   . K5O B 2 .   ? 19.163  22.891  -9.198  1.000 32.731 0 601  K5O A O1   1 ? 
HETATM 7530 O O2   . K5O B 2 .   ? 19.511  24.828  -10.628 1.000 31.982 0 601  K5O A O2   1 ? 
HETATM 7531 C C20  . K5O B 2 .   ? 15.776  20.717  -13.832 1.000 16.311 0 601  K5O A C20  1 ? 
HETATM 7532 C C21  . K5O B 2 .   ? 16.280  19.532  -13.352 1.000 16.406 0 601  K5O A C21  1 ? 
HETATM 7533 C C22  . K5O B 2 .   ? 15.272  18.925  -12.560 1.000 16.105 0 601  K5O A C22  1 ? 
HETATM 7534 C C23  . K5O B 2 .   ? 15.224  17.697  -11.858 1.000 16.227 0 601  K5O A C23  1 ? 
HETATM 7535 C C24  . K5O B 2 .   ? 16.460  16.826  -11.872 1.000 18.833 0 601  K5O A C24  1 ? 
HETATM 7536 C C25  . K5O B 2 .   ? 16.420  21.682  -14.656 1.000 19.300 0 601  K5O A C25  1 ? 
HETATM 7537 N N8   . K5O B 2 .   ? 16.877  22.502  -15.295 1.000 21.584 0 601  K5O A N8   1 ? 
HETATM 7538 C C26  . K5O B 2 .   ? 13.328  14.696  -12.064 1.000 15.972 0 601  K5O A C26  1 ? 
HETATM 7539 C C27  . K5O B 2 .   ? 12.373  13.613  -12.526 1.000 14.944 0 601  K5O A C27  1 ? 
HETATM 7540 C C28  . K5O B 2 .   ? 10.680  9.205   -12.494 1.000 13.426 0 601  K5O A C28  1 ? 
HETATM 7541 C C29  . K5O B 2 .   ? 9.264   9.359   -12.834 1.000 14.633 0 601  K5O A C29  1 ? 
HETATM 7542 C C30  . K5O B 2 .   ? 8.659   8.185   -13.166 1.000 12.745 0 601  K5O A C30  1 ? 
HETATM 7543 C C31  . K5O B 2 .   ? 7.240   7.944   -13.531 1.000 15.267 0 601  K5O A C31  1 ? 
HETATM 7544 C C32  . K5O B 2 .   ? 6.410   7.649   -12.304 1.000 18.811 0 601  K5O A C32  1 ? 
HETATM 7545 F F1   . K5O B 2 .   ? 5.104   7.543   -12.566 1.000 16.830 0 601  K5O A F1   1 ? 
HETATM 7546 F F2   . K5O B 2 .   ? 6.472   8.514   -11.297 1.000 20.061 0 601  K5O A F2   1 ? 
HETATM 7547 F F3   . K5O B 2 .   ? 6.782   6.474   -11.787 1.000 18.457 0 601  K5O A F3   1 ? 
HETATM 7548 S S2   . K5O B 2 .   ? 9.761   6.858   -13.146 1.000 14.825 0 601  K5O A S2   1 ? 
HETATM 7549 C C33  . K5O B 2 .   ? 11.050  7.864   -12.596 1.000 14.615 0 601  K5O A C33  1 ? 
HETATM 7550 N N9   . K5O B 2 .   ? 12.274  7.443   -12.302 1.000 14.012 0 601  K5O A N9   1 ? 
HETATM 7551 H H1   . K5O B 2 .   ? 15.183  9.785   -11.189 1.000 14.875 0 601  K5O A H1   1 c 
HETATM 7552 H H2   . K5O B 2 .   ? 16.265  8.635   -11.309 1.000 14.885 0 601  K5O A H2   1 c 
HETATM 7553 H H3   . K5O B 2 .   ? 15.390  8.762   -9.994  1.000 14.884 0 601  K5O A H3   1 c 
HETATM 7554 H H4   . K5O B 2 .   ? 14.611  7.151   -11.687 1.000 14.309 0 601  K5O A H4   1 c 
HETATM 7555 H H5   . K5O B 2 .   ? 10.554  11.771  -12.121 1.000 15.378 0 601  K5O A H5   1 c 
HETATM 7556 H H6   . K5O B 2 .   ? 13.266  12.024  -11.564 1.000 15.518 0 601  K5O A H6   1 c 
HETATM 7557 H H7   . K5O B 2 .   ? 11.142  13.258  -10.113 1.000 16.230 0 601  K5O A H7   1 c 
HETATM 7558 H H8   . K5O B 2 .   ? 12.168  12.184  -9.520  1.000 16.281 0 601  K5O A H8   1 c 
HETATM 7559 H H9   . K5O B 2 .   ? 13.937  13.700  -9.753  1.000 16.430 0 601  K5O A H9   1 c 
HETATM 7560 H H10  . K5O B 2 .   ? 12.807  14.383  -8.896  1.000 16.431 0 601  K5O A H10  1 c 
HETATM 7561 H H12  . K5O B 2 .   ? 14.851  15.757  -10.232 1.000 16.780 0 601  K5O A H12  1 c 
HETATM 7562 H H13  . K5O B 2 .   ? 13.741  16.450  -9.368  1.000 16.771 0 601  K5O A H13  1 c 
HETATM 7563 H H14  . K5O B 2 .   ? 12.185  18.064  -10.675 1.000 18.117 0 601  K5O A H14  1 c 
HETATM 7564 H H15  . K5O B 2 .   ? 12.240  20.049  -11.891 1.000 17.987 0 601  K5O A H15  1 c 
HETATM 7565 H H16  . K5O B 2 .   ? 12.741  21.764  -13.858 1.000 17.756 0 601  K5O A H16  1 c 
HETATM 7566 H H17  . K5O B 2 .   ? 14.004  22.604  -14.309 1.000 17.755 0 601  K5O A H17  1 c 
HETATM 7567 H H18  . K5O B 2 .   ? 12.973  22.382  -11.680 1.000 20.059 0 601  K5O A H18  1 c 
HETATM 7568 H H19  . K5O B 2 .   ? 12.768  24.761  -11.850 1.000 20.802 0 601  K5O A H19  1 c 
HETATM 7569 H H20  . K5O B 2 .   ? 11.761  23.891  -12.715 1.000 20.782 0 601  K5O A H20  1 c 
HETATM 7570 H H21  . K5O B 2 .   ? 13.014  24.577  -13.407 1.000 20.778 0 601  K5O A H21  1 c 
HETATM 7571 H H23  . K5O B 2 .   ? 14.635  21.890  -10.174 1.000 25.544 0 601  K5O A H23  1 c 
HETATM 7572 H H24  . K5O B 2 .   ? 15.787  21.679  -11.231 1.000 25.440 0 601  K5O A H24  1 c 
HETATM 7573 H H25  . K5O B 2 .   ? 16.744  22.271  -9.210  1.000 26.556 0 601  K5O A H25  1 c 
HETATM 7574 H H26  . K5O B 2 .   ? 15.853  23.576  -9.136  1.000 26.546 0 601  K5O A H26  1 c 
HETATM 7575 H H27  . K5O B 2 .   ? 17.463  25.087  -11.990 1.000 25.104 0 601  K5O A H27  1 c 
HETATM 7576 H H28  . K5O B 2 .   ? 16.365  25.438  -10.911 1.000 25.060 0 601  K5O A H28  1 c 
HETATM 7577 H H29  . K5O B 2 .   ? 15.249  24.805  -12.805 1.000 23.206 0 601  K5O A H29  1 c 
HETATM 7578 H H30  . K5O B 2 .   ? 16.130  23.509  -12.954 1.000 23.239 0 601  K5O A H30  1 c 
HETATM 7579 H H31  . K5O B 2 .   ? 17.237  25.339  -8.442  1.000 32.316 0 601  K5O A H31  1 c 
HETATM 7580 H H32  . K5O B 2 .   ? 18.674  26.007  -8.446  1.000 32.373 0 601  K5O A H32  1 c 
HETATM 7581 H H33  . K5O B 2 .   ? 18.395  24.734  -7.544  1.000 32.373 0 601  K5O A H33  1 c 
HETATM 7582 H H34  . K5O B 2 .   ? 17.130  19.180  -13.540 1.000 16.336 0 601  K5O A H34  1 c 
HETATM 7583 H H35  . K5O B 2 .   ? 16.295  16.007  -11.381 1.000 18.000 0 601  K5O A H35  1 c 
HETATM 7584 H H36  . K5O B 2 .   ? 17.197  17.304  -11.461 1.000 18.013 0 601  K5O A H36  1 c 
HETATM 7585 H H37  . K5O B 2 .   ? 16.690  16.608  -12.789 1.000 18.012 0 601  K5O A H37  1 c 
HETATM 7586 H H38  . K5O B 2 .   ? 14.236  14.345  -12.056 1.000 15.733 0 601  K5O A H38  1 c 
HETATM 7587 H H39  . K5O B 2 .   ? 13.296  15.440  -12.690 1.000 15.714 0 601  K5O A H39  1 c 
HETATM 7588 H H40  . K5O B 2 .   ? 11.461  13.981  -12.592 1.000 15.264 0 601  K5O A H40  1 c 
HETATM 7589 H H41  . K5O B 2 .   ? 12.641  13.292  -13.419 1.000 15.264 0 601  K5O A H41  1 c 
HETATM 7590 H H42  . K5O B 2 .   ? 8.813   10.195  -12.823 1.000 13.945 0 601  K5O A H42  1 c 
HETATM 7591 H H43  . K5O B 2 .   ? 7.186   7.187   -14.144 1.000 15.351 0 601  K5O A H43  1 c 
HETATM 7592 H H44  . K5O B 2 .   ? 6.880   8.731   -13.981 1.000 15.354 0 601  K5O A H44  1 c 
HETATM 7593 C C1   . PEG C 3 .   ? 20.957  -10.837 -15.933 1.000 64.924 0 602  PEG A C1   1 ? 
HETATM 7594 O O1   . PEG C 3 .   ? 20.895  -9.874  -16.963 1.000 58.326 0 602  PEG A O1   1 ? 
HETATM 7595 C C2   . PEG C 3 .   ? 22.307  -10.898 -15.277 1.000 62.388 0 602  PEG A C2   1 ? 
HETATM 7596 O O2   . PEG C 3 .   ? 22.792  -12.238 -15.325 1.000 65.337 0 602  PEG A O2   1 ? 
HETATM 7597 C C3   . PEG C 3 .   ? 23.105  -12.804 -14.054 1.000 64.793 0 602  PEG A C3   1 ? 
HETATM 7598 C C4   . PEG C 3 .   ? 22.195  -13.960 -13.794 1.000 68.142 0 602  PEG A C4   1 ? 
HETATM 7599 O O4   . PEG C 3 .   ? 21.511  -13.828 -12.566 1.000 66.930 0 602  PEG A O4   1 ? 
HETATM 7600 H H11  . PEG C 3 .   ? 20.741  -11.717 -16.307 1.000 62.664 0 602  PEG A H11  1 c 
HETATM 7601 H H12  . PEG C 3 .   ? 20.283  -10.622 -15.257 1.000 62.342 0 602  PEG A H12  1 c 
HETATM 7602 H HO1  . PEG C 3 .   ? 20.107  -9.868  -17.268 0.000 57.860 0 602  PEG A HO1  1 c 
HETATM 7603 H H21  . PEG C 3 .   ? 22.237  -10.596 -14.347 1.000 63.336 0 602  PEG A H21  1 c 
HETATM 7604 H H22  . PEG C 3 .   ? 22.931  -10.305 -15.747 1.000 63.407 0 602  PEG A H22  1 c 
HETATM 7605 H H31  . PEG C 3 .   ? 23.000  -12.130 -13.348 1.000 65.644 0 602  PEG A H31  1 c 
HETATM 7606 H H32  . PEG C 3 .   ? 24.038  -13.109 -14.050 1.000 65.664 0 602  PEG A H32  1 c 
HETATM 7607 H H41  . PEG C 3 .   ? 22.718  -14.788 -13.782 1.000 67.075 0 602  PEG A H41  1 c 
HETATM 7608 H H42  . PEG C 3 .   ? 21.538  -14.025 -14.519 1.000 67.065 0 602  PEG A H42  1 c 
HETATM 7609 H HO4  . PEG C 3 .   ? 22.093  -13.814 -11.923 1.000 67.259 0 602  PEG A HO4  1 c 
HETATM 7610 C C1   . PEG D 3 .   ? -7.928  9.939   -6.184  1.000 55.043 0 603  PEG A C1   1 ? 
HETATM 7611 O O1   . PEG D 3 .   ? -7.782  11.287  -5.824  1.000 59.363 0 603  PEG A O1   1 ? 
HETATM 7612 C C2   . PEG D 3 .   ? -6.657  9.215   -6.041  1.000 49.666 0 603  PEG A C2   1 ? 
HETATM 7613 O O2   . PEG D 3 .   ? -6.917  7.888   -5.605  1.000 49.684 0 603  PEG A O2   1 ? 
HETATM 7614 C C3   . PEG D 3 .   ? -6.588  7.663   -4.239  1.000 47.614 0 603  PEG A C3   1 ? 
HETATM 7615 C C4   . PEG D 3 .   ? -7.060  6.303   -3.821  1.000 50.530 0 603  PEG A C4   1 ? 
HETATM 7616 O O4   . PEG D 3 .   ? -7.512  6.276   -2.479  1.000 51.314 0 603  PEG A O4   1 ? 
HETATM 7617 H H11  . PEG D 3 .   ? -8.231  9.884   -7.115  1.000 54.708 0 603  PEG A H11  1 c 
HETATM 7618 H H12  . PEG D 3 .   ? -8.608  9.524   -5.614  1.000 54.681 0 603  PEG A H12  1 c 
HETATM 7619 H HO1  . PEG D 3 .   ? -8.553  11.669  -5.902  0.000 58.950 0 603  PEG A HO1  1 c 
HETATM 7620 H H21  . PEG D 3 .   ? -6.082  9.675   -5.393  1.000 50.867 0 603  PEG A H21  1 c 
HETATM 7621 H H22  . PEG D 3 .   ? -6.191  9.193   -6.903  1.000 50.447 0 603  PEG A H22  1 c 
HETATM 7622 H H31  . PEG D 3 .   ? -7.020  8.340   -3.690  1.000 49.464 0 603  PEG A H31  1 c 
HETATM 7623 H H32  . PEG D 3 .   ? -5.616  7.732   -4.113  1.000 48.975 0 603  PEG A H32  1 c 
HETATM 7624 H H41  . PEG D 3 .   ? -6.326  5.662   -3.924  1.000 50.008 0 603  PEG A H41  1 c 
HETATM 7625 H H42  . PEG D 3 .   ? -7.793  6.022   -4.409  1.000 49.904 0 603  PEG A H42  1 c 
HETATM 7626 H HO4  . PEG D 3 .   ? -8.293  6.623   -2.442  1.000 51.267 0 603  PEG A HO4  1 c 
HETATM 7627 S S    . SO4 E 4 .   ? 24.905  -11.569 12.906  1.000 75.555 0 604  SO4 A S    1 ? 
HETATM 7628 O O1   . SO4 E 4 .   ? 26.230  -11.923 13.344  1.000 84.681 0 604  SO4 A O1   1 ? 
HETATM 7629 O O2   . SO4 E 4 .   ? 24.056  -11.364 14.057  1.000 68.440 0 604  SO4 A O2   1 ? 
HETATM 7630 O O3   . SO4 E 4 .   ? 24.959  -10.356 12.123  1.000 74.951 0 604  SO4 A O3   1 ? 
HETATM 7631 O O4   . SO4 E 4 .   ? 24.388  -12.641 12.094  1.000 79.332 0 604  SO4 A O4   1 ? 
HETATM 7632 S S    . DMS F 5 .   ? 14.258  -0.323  15.504  1.000 60.024 0 605  DMS A S    1 ? 
HETATM 7633 O O    . DMS F 5 .   ? 14.204  -0.479  14.011  1.000 52.611 0 605  DMS A O    1 ? 
HETATM 7634 C C1   . DMS F 5 .   ? 15.130  1.174   15.852  1.000 60.840 0 605  DMS A C1   1 ? 
HETATM 7635 C C2   . DMS F 5 .   ? 15.479  -1.503  16.028  1.000 67.165 0 605  DMS A C2   1 ? 
HETATM 7636 H H11  . DMS F 5 .   ? 14.878  1.496   16.729  1.000 60.556 0 605  DMS A H11  1 c 
HETATM 7637 H H12  . DMS F 5 .   ? 14.905  1.839   15.186  1.000 60.445 0 605  DMS A H12  1 c 
HETATM 7638 H H13  . DMS F 5 .   ? 16.080  0.999   15.833  1.000 60.443 0 605  DMS A H13  1 c 
HETATM 7639 H H21  . DMS F 5 .   ? 16.277  -1.389  15.499  1.000 64.779 0 605  DMS A H21  1 c 
HETATM 7640 H H22  . DMS F 5 .   ? 15.134  -2.398  15.904  1.000 65.152 0 605  DMS A H22  1 c 
HETATM 7641 H H23  . DMS F 5 .   ? 15.685  -1.362  16.962  1.000 65.153 0 605  DMS A H23  1 c 
HETATM 7642 O O1   . PG4 G 6 .   ? 22.440  12.997  17.596  1.000 59.343 0 606  PG4 A O1   1 ? 
HETATM 7643 C C1   . PG4 G 6 .   ? 22.423  12.212  18.774  1.000 47.364 0 606  PG4 A C1   1 ? 
HETATM 7644 C C2   . PG4 G 6 .   ? 22.172  10.779  18.481  1.000 52.537 0 606  PG4 A C2   1 ? 
HETATM 7645 O O2   . PG4 G 6 .   ? 21.580  10.595  17.187  1.000 60.452 0 606  PG4 A O2   1 ? 
HETATM 7646 C C3   . PG4 G 6 .   ? 22.512  10.262  16.159  1.000 43.526 0 606  PG4 A C3   1 ? 
HETATM 7647 C C4   . PG4 G 6 .   ? 22.096  9.055   15.337  1.000 43.328 0 606  PG4 A C4   1 ? 
HETATM 7648 O O3   . PG4 G 6 .   ? 23.262  8.445   14.757  1.000 39.713 0 606  PG4 A O3   1 ? 
HETATM 7649 C C5   . PG4 G 6 .   ? 23.905  9.251   13.767  1.000 39.738 0 606  PG4 A C5   1 ? 
HETATM 7650 C C6   . PG4 G 6 .   ? 25.434  9.169   13.792  1.000 40.759 0 606  PG4 A C6   1 ? 
HETATM 7651 O O4   . PG4 G 6 .   ? 25.989  10.429  14.218  1.000 35.865 0 606  PG4 A O4   1 ? 
HETATM 7652 C C7   . PG4 G 6 .   ? 26.820  11.103  13.273  1.000 40.263 0 606  PG4 A C7   1 ? 
HETATM 7653 C C8   . PG4 G 6 .   ? 27.224  12.462  13.795  1.000 39.143 0 606  PG4 A C8   1 ? 
HETATM 7654 O O5   . PG4 G 6 .   ? 26.210  13.441  13.634  1.000 45.763 0 606  PG4 A O5   1 ? 
HETATM 7655 H HO1  . PG4 G 6 .   ? 22.571  13.805  17.737  0.000 58.460 0 606  PG4 A HO1  1 c 
HETATM 7656 H H11  . PG4 G 6 .   ? 21.723  12.547  19.372  1.000 51.173 0 606  PG4 A H11  1 c 
HETATM 7657 H H12  . PG4 G 6 .   ? 23.285  12.303  19.231  1.000 51.173 0 606  PG4 A H12  1 c 
HETATM 7658 H H21  . PG4 G 6 .   ? 21.574  10.408  19.166  1.000 53.014 0 606  PG4 A H21  1 c 
HETATM 7659 H H22  . PG4 G 6 .   ? 23.019  10.288  18.525  1.000 52.912 0 606  PG4 A H22  1 c 
HETATM 7660 H H31  . PG4 G 6 .   ? 23.381  10.078  16.563  1.000 47.060 0 606  PG4 A H31  1 c 
HETATM 7661 H H32  . PG4 G 6 .   ? 22.617  11.036  15.565  1.000 46.962 0 606  PG4 A H32  1 c 
HETATM 7662 H H41  . PG4 G 6 .   ? 21.480  9.334   14.625  1.000 42.440 0 606  PG4 A H41  1 c 
HETATM 7663 H H42  . PG4 G 6 .   ? 21.634  8.407   15.909  1.000 42.359 0 606  PG4 A H42  1 c 
HETATM 7664 H H51  . PG4 G 6 .   ? 23.637  10.186  13.887  1.000 40.005 0 606  PG4 A H51  1 c 
HETATM 7665 H H52  . PG4 G 6 .   ? 23.590  8.970   12.881  1.000 39.887 0 606  PG4 A H52  1 c 
HETATM 7666 H H61  . PG4 G 6 .   ? 25.767  8.945   12.895  1.000 39.310 0 606  PG4 A H61  1 c 
HETATM 7667 H H62  . PG4 G 6 .   ? 25.716  8.459   14.409  1.000 39.307 0 606  PG4 A H62  1 c 
HETATM 7668 H H71  . PG4 G 6 .   ? 26.335  11.207  12.425  1.000 38.921 0 606  PG4 A H71  1 c 
HETATM 7669 H H72  . PG4 G 6 .   ? 27.623  10.564  13.099  1.000 38.919 0 606  PG4 A H72  1 c 
HETATM 7670 H H81  . PG4 G 6 .   ? 28.030  12.759  13.324  1.000 40.889 0 606  PG4 A H81  1 c 
HETATM 7671 H H82  . PG4 G 6 .   ? 27.442  12.386  14.748  1.000 40.888 0 606  PG4 A H82  1 c 
HETATM 7672 H HO5  . PG4 G 6 .   ? 25.501  13.177  14.013  1.000 43.583 0 606  PG4 A HO5  1 c 
HETATM 7673 S S    . SO4 H 4 .   ? -2.856  11.287  6.318   1.000 66.197 0 607  SO4 A S    1 ? 
HETATM 7674 O O1   . SO4 H 4 .   ? -2.019  11.280  5.159   1.000 50.540 0 607  SO4 A O1   1 ? 
HETATM 7675 O O2   . SO4 H 4 .   ? -2.243  12.123  7.344   1.000 57.568 0 607  SO4 A O2   1 ? 
HETATM 7676 O O3   . SO4 H 4 .   ? -4.158  11.825  5.998   1.000 47.863 0 607  SO4 A O3   1 ? 
HETATM 7677 O O4   . SO4 H 4 .   ? -2.986  9.923   6.774   1.000 53.607 0 607  SO4 A O4   1 ? 
HETATM 7678 O O1   . PG4 I 6 .   ? 27.318  -5.372  -18.348 1.000 74.364 0 608  PG4 A O1   1 ? 
HETATM 7679 C C1   . PG4 I 6 .   ? 27.328  -4.382  -19.349 1.000 73.367 0 608  PG4 A C1   1 ? 
HETATM 7680 C C2   . PG4 I 6 .   ? 27.102  -3.001  -18.792 1.000 71.135 0 608  PG4 A C2   1 ? 
HETATM 7681 O O2   . PG4 I 6 .   ? 28.077  -2.658  -17.801 1.000 72.611 0 608  PG4 A O2   1 ? 
HETATM 7682 C C3   . PG4 I 6 .   ? 28.011  -1.294  -17.367 1.000 64.452 0 608  PG4 A C3   1 ? 
HETATM 7683 C C4   . PG4 I 6 .   ? 28.238  -0.333  -18.532 1.000 66.477 0 608  PG4 A C4   1 ? 
HETATM 7684 O O3   . PG4 I 6 .   ? 28.311  1.032   -18.108 1.000 62.005 0 608  PG4 A O3   1 ? 
HETATM 7685 C C5   . PG4 I 6 .   ? 27.046  1.629   -17.815 1.000 64.582 0 608  PG4 A C5   1 ? 
HETATM 7686 C C6   . PG4 I 6 .   ? 26.769  2.767   -18.750 1.000 59.127 0 608  PG4 A C6   1 ? 
HETATM 7687 O O4   . PG4 I 6 .   ? 25.363  2.981   -18.874 1.000 62.175 0 608  PG4 A O4   1 ? 
HETATM 7688 C C7   . PG4 I 6 .   ? 25.045  4.062   -19.749 1.000 53.623 0 608  PG4 A C7   1 ? 
HETATM 7689 C C8   . PG4 I 6 .   ? 24.345  3.583   -20.983 1.000 58.833 0 608  PG4 A C8   1 ? 
HETATM 7690 O O5   . PG4 I 6 .   ? 24.524  4.462   -22.087 1.000 55.769 0 608  PG4 A O5   1 ? 
HETATM 7691 H HO1  . PG4 I 6 .   ? 27.410  -6.115  -18.615 0.000 74.380 0 608  PG4 A HO1  1 c 
HETATM 7692 H H11  . PG4 I 6 .   ? 26.626  -4.584  -20.003 1.000 73.089 0 608  PG4 A H11  1 c 
HETATM 7693 H H12  . PG4 I 6 .   ? 28.191  -4.406  -19.813 1.000 73.090 0 608  PG4 A H12  1 c 
HETATM 7694 H H21  . PG4 I 6 .   ? 26.207  -2.953  -18.397 1.000 70.405 0 608  PG4 A H21  1 c 
HETATM 7695 H H22  . PG4 I 6 .   ? 27.141  -2.353  -19.525 1.000 71.390 0 608  PG4 A H22  1 c 
HETATM 7696 H H31  . PG4 I 6 .   ? 28.692  -1.138  -16.677 1.000 66.665 0 608  PG4 A H31  1 c 
HETATM 7697 H H32  . PG4 I 6 .   ? 27.131  -1.121  -16.969 1.000 66.207 0 608  PG4 A H32  1 c 
HETATM 7698 H H41  . PG4 I 6 .   ? 27.509  -0.427  -19.181 1.000 64.768 0 608  PG4 A H41  1 c 
HETATM 7699 H H42  . PG4 I 6 .   ? 29.075  -0.573  -18.987 1.000 64.898 0 608  PG4 A H42  1 c 
HETATM 7700 H H51  . PG4 I 6 .   ? 27.048  1.960   -16.891 1.000 62.050 0 608  PG4 A H51  1 c 
HETATM 7701 H H52  . PG4 I 6 .   ? 26.336  0.961   -17.893 1.000 62.335 0 608  PG4 A H52  1 c 
HETATM 7702 H H61  . PG4 I 6 .   ? 27.151  2.567   -19.633 1.000 60.909 0 608  PG4 A H61  1 c 
HETATM 7703 H H62  . PG4 I 6 .   ? 27.198  3.581   -18.410 1.000 60.656 0 608  PG4 A H62  1 c 
HETATM 7704 H H71  . PG4 I 6 .   ? 25.869  4.532   -20.005 1.000 56.336 0 608  PG4 A H71  1 c 
HETATM 7705 H H72  . PG4 I 6 .   ? 24.468  4.701   -19.277 1.000 56.256 0 608  PG4 A H72  1 c 
HETATM 7706 H H81  . PG4 I 6 .   ? 23.387  3.496   -20.796 1.000 56.831 0 608  PG4 A H81  1 c 
HETATM 7707 H H82  . PG4 I 6 .   ? 24.690  2.700   -21.223 1.000 56.644 0 608  PG4 A H82  1 c 
HETATM 7708 H HO5  . PG4 I 6 .   ? 24.214  5.225   -21.891 1.000 56.668 0 608  PG4 A HO5  1 c 
HETATM 7709 S S    . SO4 J 4 .   ? 29.041  31.716  -18.331 1.000 53.041 0 609  SO4 A S    1 ? 
HETATM 7710 O O1   . SO4 J 4 .   ? 30.487  31.791  -18.285 1.000 61.120 0 609  SO4 A O1   1 ? 
HETATM 7711 O O2   . SO4 J 4 .   ? 28.554  31.214  -17.066 1.000 55.414 0 609  SO4 A O2   1 ? 
HETATM 7712 O O3   . SO4 J 4 .   ? 28.481  33.076  -18.506 1.000 48.630 0 609  SO4 A O3   1 ? 
HETATM 7713 O O4   . SO4 J 4 .   ? 28.663  30.798  -19.458 1.000 39.550 0 609  SO4 A O4   1 ? 
HETATM 7714 S S    . DMS K 5 .   ? 10.181  8.014   -8.620  1.000 55.660 0 610  DMS A S    1 ? 
HETATM 7715 O O    . DMS K 5 .   ? 10.786  8.794   -7.507  1.000 64.852 0 610  DMS A O    1 ? 
HETATM 7716 C C1   . DMS K 5 .   ? 8.925   7.064   -7.878  1.000 43.965 0 610  DMS A C1   1 ? 
HETATM 7717 C C2   . DMS K 5 .   ? 11.357  6.748   -8.979  1.000 33.526 0 610  DMS A C2   1 ? 
HETATM 7718 H H11  . DMS K 5 .   ? 8.487   6.528   -8.552  1.000 46.031 0 610  DMS A H11  1 c 
HETATM 7719 H H12  . DMS K 5 .   ? 8.279   7.653   -7.465  1.000 46.317 0 610  DMS A H12  1 c 
HETATM 7720 H H13  . DMS K 5 .   ? 9.312   6.486   -7.206  1.000 46.459 0 610  DMS A H13  1 c 
HETATM 7721 H H21  . DMS K 5 .   ? 11.464  6.180   -8.204  1.000 38.238 0 610  DMS A H21  1 c 
HETATM 7722 H H22  . DMS K 5 .   ? 12.206  7.153   -9.203  1.000 38.199 0 610  DMS A H22  1 c 
HETATM 7723 H H23  . DMS K 5 .   ? 11.043  6.220   -9.726  1.000 38.041 0 610  DMS A H23  1 c 
HETATM 7724 C C1   . EDO L 7 .   ? -9.184  3.410   7.100   1.000 48.060 0 611  EDO A C1   1 ? 
HETATM 7725 O O1   . EDO L 7 .   ? -7.850  3.895   7.121   1.000 50.274 0 611  EDO A O1   1 ? 
HETATM 7726 C C2   . EDO L 7 .   ? -10.105 4.411   6.553   1.000 49.381 0 611  EDO A C2   1 ? 
HETATM 7727 O O2   . EDO L 7 .   ? -10.387 4.086   5.212   1.000 49.732 0 611  EDO A O2   1 ? 
HETATM 7728 H H11  . EDO L 7 .   ? -9.460  3.182   8.013   1.000 48.883 0 611  EDO A H11  1 c 
HETATM 7729 H H12  . EDO L 7 .   ? -9.225  2.597   6.554   1.000 48.892 0 611  EDO A H12  1 c 
HETATM 7730 H HO1  . EDO L 7 .   ? -7.353  3.284   7.427   0.000 49.650 0 611  EDO A HO1  1 c 
HETATM 7731 H H21  . EDO L 7 .   ? -9.695  5.299   6.601   1.000 49.161 0 611  EDO A H21  1 c 
HETATM 7732 H H22  . EDO L 7 .   ? -10.934 4.415   7.075   1.000 49.155 0 611  EDO A H22  1 c 
HETATM 7733 H HO2  . EDO L 7 .   ? -10.952 3.456   5.189   1.000 49.603 0 611  EDO A HO2  1 c 
HETATM 7734 O O    . HOH M 8 .   ? 3.988   12.297  8.440   1.000 47.081 0 701  HOH A O    1 ? 
HETATM 7735 O O    . HOH M 8 .   ? -2.507  11.789  -23.065 1.000 26.503 0 702  HOH A O    1 ? 
HETATM 7736 O O    . HOH M 8 .   ? 3.108   20.166  -31.327 1.000 31.004 0 703  HOH A O    1 ? 
HETATM 7737 O O    . HOH M 8 .   ? -8.082  -16.508 -18.617 1.000 44.234 0 704  HOH A O    1 ? 
HETATM 7738 O O    . HOH M 8 .   ? -4.545  -6.444  1.099   1.000 42.880 0 705  HOH A O    1 ? 
HETATM 7739 O O    . HOH M 8 .   ? 13.331  4.977   15.461  1.000 41.631 0 706  HOH A O    1 ? 
HETATM 7740 O O    . HOH M 8 .   ? 7.773   -13.117 -11.788 1.000 34.729 0 707  HOH A O    1 ? 
HETATM 7741 O O    . HOH M 8 .   ? 4.187   -7.728  -29.984 1.000 35.518 0 708  HOH A O    1 ? 
HETATM 7742 O O    . HOH M 8 .   ? 10.669  14.638  -29.702 1.000 27.079 0 709  HOH A O    1 ? 
HETATM 7743 O O    . HOH M 8 .   ? 30.640  28.198  -20.038 1.000 38.370 0 710  HOH A O    1 ? 
HETATM 7744 O O    . HOH M 8 .   ? -0.498  -0.669  -25.326 1.000 38.207 0 711  HOH A O    1 ? 
HETATM 7745 O O    . HOH M 8 .   ? -4.265  -17.155 -5.011  1.000 47.561 0 712  HOH A O    1 ? 
HETATM 7746 O O    . HOH M 8 .   ? 32.386  38.916  -21.308 1.000 33.621 0 713  HOH A O    1 ? 
HETATM 7747 O O    . HOH M 8 .   ? -4.119  -15.717 -19.559 1.000 35.192 0 714  HOH A O    1 ? 
HETATM 7748 O O    . HOH M 8 .   ? 12.517  16.409  -31.566 1.000 32.685 0 715  HOH A O    1 ? 
HETATM 7749 O O    . HOH M 8 .   ? 24.107  -9.166  6.870   1.000 44.582 0 716  HOH A O    1 ? 
HETATM 7750 O O    . HOH M 8 .   ? 14.540  -5.593  13.068  1.000 33.612 0 717  HOH A O    1 ? 
HETATM 7751 O O    . HOH M 8 .   ? 28.414  2.692   5.405   1.000 38.222 0 718  HOH A O    1 ? 
HETATM 7752 O O    . HOH M 8 .   ? 6.318   16.705  -11.486 1.000 36.939 0 719  HOH A O    1 ? 
HETATM 7753 O O    . HOH M 8 .   ? 1.054   8.160   -12.025 1.000 30.458 0 720  HOH A O    1 ? 
HETATM 7754 O O    . HOH M 8 .   ? 5.500   -15.755 -18.429 1.000 45.459 0 721  HOH A O    1 ? 
HETATM 7755 O O    . HOH M 8 .   ? -12.393 -10.367 -12.026 1.000 42.061 0 722  HOH A O    1 ? 
HETATM 7756 O O    . HOH M 8 .   ? 9.838   -11.731 -15.032 1.000 30.441 0 723  HOH A O    1 ? 
HETATM 7757 O O    . HOH M 8 .   ? 17.983  11.248  -4.013  1.000 31.578 0 724  HOH A O    1 ? 
HETATM 7758 O O    . HOH M 8 .   ? 31.929  3.471   -16.059 1.000 41.572 0 725  HOH A O    1 ? 
HETATM 7759 O O    . HOH M 8 .   ? -0.302  -11.825 -29.923 1.000 33.286 0 726  HOH A O    1 ? 
HETATM 7760 O O    . HOH M 8 .   ? 21.994  44.569  -22.850 1.000 39.491 0 727  HOH A O    1 ? 
HETATM 7761 O O    . HOH M 8 .   ? -11.760 -6.995  -10.738 1.000 36.995 0 728  HOH A O    1 ? 
HETATM 7762 O O    . HOH M 8 .   ? 15.032  17.481  2.308   1.000 38.492 0 729  HOH A O    1 ? 
HETATM 7763 O O    . HOH M 8 .   ? -0.539  30.838  -27.230 1.000 35.527 0 730  HOH A O    1 ? 
HETATM 7764 O O    . HOH M 8 .   ? -1.926  -9.643  -27.097 1.000 29.325 0 731  HOH A O    1 ? 
HETATM 7765 O O    . HOH M 8 .   ? 18.760  19.541  -11.033 1.000 37.335 0 732  HOH A O    1 ? 
HETATM 7766 O O    . HOH M 8 .   ? -8.827  -14.442 -17.296 1.000 35.202 0 733  HOH A O    1 ? 
HETATM 7767 O O    . HOH M 8 .   ? 13.228  24.019  -32.528 1.000 26.160 0 734  HOH A O    1 ? 
HETATM 7768 O O    . HOH M 8 .   ? 22.745  19.461  -23.805 1.000 33.161 0 735  HOH A O    1 ? 
HETATM 7769 O O    . HOH M 8 .   ? 31.177  -0.731  -13.981 1.000 38.377 0 736  HOH A O    1 ? 
HETATM 7770 O O    . HOH M 8 .   ? 8.735   23.449  -38.844 1.000 36.621 0 737  HOH A O    1 ? 
HETATM 7771 O O    . HOH M 8 .   ? 17.981  -11.164 14.161  1.000 37.618 0 738  HOH A O    1 ? 
HETATM 7772 O O    . HOH M 8 .   ? 11.811  34.608  -40.748 1.000 43.711 0 739  HOH A O    1 ? 
HETATM 7773 O O    . HOH M 8 .   ? 5.944   -9.260  -20.367 1.000 26.867 0 740  HOH A O    1 ? 
HETATM 7774 O O    . HOH M 8 .   ? 30.979  1.025   4.360   1.000 44.798 0 741  HOH A O    1 ? 
HETATM 7775 O O    . HOH M 8 .   ? 23.558  6.706   11.605  1.000 27.400 0 742  HOH A O    1 ? 
HETATM 7776 O O    . HOH M 8 .   ? 6.151   4.923   7.386   1.000 34.205 0 743  HOH A O    1 ? 
HETATM 7777 O O    . HOH M 8 .   ? 28.581  47.244  -10.369 1.000 30.139 0 744  HOH A O    1 ? 
HETATM 7778 O O    . HOH M 8 .   ? 32.791  42.651  -18.402 1.000 52.346 0 745  HOH A O    1 ? 
HETATM 7779 O O    . HOH M 8 .   ? 23.501  17.313  -6.816  1.000 28.656 0 746  HOH A O    1 ? 
HETATM 7780 O O    . HOH M 8 .   ? 2.281   34.984  -33.814 1.000 19.904 0 747  HOH A O    1 ? 
HETATM 7781 O O    . HOH M 8 .   ? -11.079 -10.579 -3.541  1.000 38.658 0 748  HOH A O    1 ? 
HETATM 7782 O O    . HOH M 8 .   ? 6.901   -14.926 -10.021 1.000 38.187 0 749  HOH A O    1 ? 
HETATM 7783 O O    . HOH M 8 .   ? 9.011   33.469  -21.221 1.000 15.352 0 750  HOH A O    1 ? 
HETATM 7784 O O    . HOH M 8 .   ? 5.850   11.815  -11.688 1.000 34.093 0 751  HOH A O    1 ? 
HETATM 7785 O O    . HOH M 8 .   ? 10.013  22.290  -10.783 1.000 34.748 0 752  HOH A O    1 ? 
HETATM 7786 O O    . HOH M 8 .   ? 26.312  -7.763  9.653   1.000 44.070 0 753  HOH A O    1 ? 
HETATM 7787 O O    . HOH M 8 .   ? 27.413  26.975  -27.056 1.000 39.937 0 754  HOH A O    1 ? 
HETATM 7788 O O    . HOH M 8 .   ? 16.541  12.171  -9.057  1.000 23.391 0 755  HOH A O    1 ? 
HETATM 7789 O O    . HOH M 8 .   ? 3.226   17.485  -24.595 1.000 22.617 0 756  HOH A O    1 ? 
HETATM 7790 O O    . HOH M 8 .   ? 31.121  17.612  -6.541  1.000 43.504 0 757  HOH A O    1 ? 
HETATM 7791 O O    . HOH M 8 .   ? 24.313  -2.036  13.315  1.000 33.978 0 758  HOH A O    1 ? 
HETATM 7792 O O    . HOH M 8 .   ? -0.935  9.269   -33.718 1.000 34.249 0 759  HOH A O    1 ? 
HETATM 7793 O O    . HOH M 8 .   ? 0.929   29.613  -16.822 1.000 21.904 0 760  HOH A O    1 ? 
HETATM 7794 O O    . HOH M 8 .   ? 2.172   23.660  -37.550 1.000 41.089 0 761  HOH A O    1 ? 
HETATM 7795 O O    . HOH M 8 .   ? 14.137  14.332  -30.117 1.000 33.693 0 762  HOH A O    1 ? 
HETATM 7796 O O    . HOH M 8 .   ? 19.729  44.850  -25.851 1.000 48.251 0 763  HOH A O    1 ? 
HETATM 7797 O O    . HOH M 8 .   ? 4.329   28.991  -33.865 1.000 22.361 0 764  HOH A O    1 ? 
HETATM 7798 O O    . HOH M 8 .   ? 18.175  12.718  -31.781 1.000 34.385 0 765  HOH A O    1 ? 
HETATM 7799 O O    . HOH M 8 .   ? 1.247   15.287  5.493   1.000 47.946 0 766  HOH A O    1 ? 
HETATM 7800 O O    . HOH M 8 .   ? 35.902  3.940   -4.382  1.000 40.328 0 767  HOH A O    1 ? 
HETATM 7801 O O    . HOH M 8 .   ? 22.181  -14.956 -5.306  1.000 44.113 0 768  HOH A O    1 ? 
HETATM 7802 O O    . HOH M 8 .   ? 28.087  -1.737  -0.038  1.000 36.678 0 769  HOH A O    1 ? 
HETATM 7803 O O    . HOH M 8 .   ? 3.020   -11.861 9.485   1.000 35.251 0 770  HOH A O    1 ? 
HETATM 7804 O O    . HOH M 8 .   ? 9.439   3.777   1.989   1.000 25.722 0 771  HOH A O    1 ? 
HETATM 7805 O O    . HOH M 8 .   ? 13.527  33.915  -20.344 1.000 18.219 0 772  HOH A O    1 ? 
HETATM 7806 O O    . HOH M 8 .   ? 18.339  13.703  -7.852  1.000 27.404 0 773  HOH A O    1 ? 
HETATM 7807 O O    . HOH M 8 .   ? 9.655   0.528   -2.683  1.000 17.589 0 774  HOH A O    1 ? 
HETATM 7808 O O    . HOH M 8 .   ? 20.882  -3.363  -24.376 1.000 36.400 0 775  HOH A O    1 ? 
HETATM 7809 O O    . HOH M 8 .   ? 16.548  8.730   20.357  1.000 51.845 0 776  HOH A O    1 ? 
HETATM 7810 O O    . HOH M 8 .   ? -1.512  42.360  -23.685 1.000 48.240 0 777  HOH A O    1 ? 
HETATM 7811 O O    . HOH M 8 .   ? 2.979   28.318  -31.573 1.000 21.323 0 778  HOH A O    1 ? 
HETATM 7812 O O    . HOH M 8 .   ? 22.217  -17.621 0.684   1.000 47.532 0 779  HOH A O    1 ? 
HETATM 7813 O O    . HOH M 8 .   ? 14.496  -14.203 -5.354  1.000 30.221 0 780  HOH A O    1 ? 
HETATM 7814 O O    . HOH M 8 .   ? 31.907  11.300  -9.471  1.000 27.160 0 781  HOH A O    1 ? 
HETATM 7815 O O    . HOH M 8 .   ? 28.588  37.739  -17.032 1.000 24.682 0 782  HOH A O    1 ? 
HETATM 7816 O O    . HOH M 8 .   ? 5.965   25.398  -38.059 1.000 24.567 0 783  HOH A O    1 ? 
HETATM 7817 O O    . HOH M 8 .   ? -4.907  5.179   -20.744 1.000 20.575 0 784  HOH A O    1 ? 
HETATM 7818 O O    . HOH M 8 .   ? 6.565   -5.159  -22.991 1.000 35.193 0 785  HOH A O    1 ? 
HETATM 7819 O O    . HOH M 8 .   ? 34.674  10.696  -8.118  1.000 32.438 0 786  HOH A O    1 ? 
HETATM 7820 O O    . HOH M 8 .   ? 4.147   8.722   -8.176  1.000 26.162 0 787  HOH A O    1 ? 
HETATM 7821 O O    . HOH M 8 .   ? 14.186  23.774  -29.987 1.000 21.296 0 788  HOH A O    1 ? 
HETATM 7822 O O    . HOH M 8 .   ? -11.356 -6.880  -5.706  1.000 47.213 0 789  HOH A O    1 ? 
HETATM 7823 O O    . HOH M 8 .   ? -6.413  -20.004 -5.823  1.000 43.661 0 790  HOH A O    1 ? 
HETATM 7824 O O    . HOH M 8 .   ? -6.087  -8.601  0.656   1.000 50.155 0 791  HOH A O    1 ? 
HETATM 7825 O O    . HOH M 8 .   ? 29.246  -3.291  -7.903  1.000 41.890 0 792  HOH A O    1 ? 
HETATM 7826 O O    . HOH M 8 .   ? 9.688   8.444   -3.482  1.000 19.548 0 793  HOH A O    1 ? 
HETATM 7827 O O    . HOH M 8 .   ? 23.969  -4.101  14.892  1.000 37.991 0 794  HOH A O    1 ? 
HETATM 7828 O O    . HOH M 8 .   ? 7.447   7.919   -5.026  1.000 20.432 0 795  HOH A O    1 ? 
HETATM 7829 O O    . HOH M 8 .   ? 2.138   9.960   -26.421 1.000 16.182 0 796  HOH A O    1 ? 
HETATM 7830 O O    . HOH M 8 .   ? -6.207  4.282   -24.207 1.000 24.549 0 797  HOH A O    1 ? 
HETATM 7831 O O    . HOH M 8 .   ? 5.867   32.672  -39.450 1.000 18.595 0 798  HOH A O    1 ? 
HETATM 7832 O O    . HOH M 8 .   ? 19.862  -13.000 2.832   1.000 32.190 0 799  HOH A O    1 ? 
HETATM 7833 O O    . HOH M 8 .   ? 12.552  44.661  -31.912 1.000 26.590 0 800  HOH A O    1 ? 
HETATM 7834 O O    . HOH M 8 .   ? -16.336 3.287   1.810   1.000 49.932 0 801  HOH A O    1 ? 
HETATM 7835 O O    . HOH M 8 .   ? 25.659  41.852  -24.178 1.000 23.398 0 802  HOH A O    1 ? 
HETATM 7836 O O    . HOH M 8 .   ? -1.995  -3.901  6.051   1.000 34.442 0 803  HOH A O    1 ? 
HETATM 7837 O O    . HOH M 8 .   ? 10.053  12.647  6.883   1.000 36.964 0 804  HOH A O    1 ? 
HETATM 7838 O O    . HOH M 8 .   ? 8.391   -13.796 11.594  1.000 35.426 0 805  HOH A O    1 ? 
HETATM 7839 O O    . HOH M 8 .   ? 17.896  8.607   -31.229 1.000 33.497 0 806  HOH A O    1 ? 
HETATM 7840 O O    . HOH M 8 .   ? 9.945   -19.011 4.711   1.000 42.873 0 807  HOH A O    1 ? 
HETATM 7841 O O    . HOH M 8 .   ? 27.992  0.187   -4.592  1.000 28.187 0 808  HOH A O    1 ? 
HETATM 7842 O O    . HOH M 8 .   ? 8.016   -11.648 -4.695  1.000 35.747 0 809  HOH A O    1 ? 
HETATM 7843 O O    . HOH M 8 .   ? 24.982  -0.501  -18.721 1.000 35.403 0 810  HOH A O    1 ? 
HETATM 7844 O O    . HOH M 8 .   ? 14.953  37.816  -17.906 1.000 20.535 0 811  HOH A O    1 ? 
HETATM 7845 O O    . HOH M 8 .   ? 25.677  44.372  -17.661 1.000 30.548 0 812  HOH A O    1 ? 
HETATM 7846 O O    . HOH M 8 .   ? 7.098   2.879   -5.536  1.000 17.326 0 813  HOH A O    1 ? 
HETATM 7847 O O    . HOH M 8 .   ? 0.999   -18.544 -11.098 1.000 32.909 0 814  HOH A O    1 ? 
HETATM 7848 O O    . HOH M 8 .   ? 15.644  12.162  -24.968 1.000 16.509 0 815  HOH A O    1 ? 
HETATM 7849 O O    . HOH M 8 .   ? -1.764  3.185   -14.466 1.000 15.768 0 816  HOH A O    1 ? 
HETATM 7850 O O    . HOH M 8 .   ? 14.075  0.350   -26.274 1.000 38.749 0 817  HOH A O    1 ? 
HETATM 7851 O O    . HOH M 8 .   ? -0.835  -3.064  -27.322 1.000 25.378 0 818  HOH A O    1 ? 
HETATM 7852 O O    . HOH M 8 .   ? -5.993  9.418   -29.159 1.000 22.884 0 819  HOH A O    1 ? 
HETATM 7853 O O    . HOH M 8 .   ? 5.864   8.923   -1.212  1.000 18.771 0 820  HOH A O    1 ? 
HETATM 7854 O O    . HOH M 8 .   ? -10.217 -13.730 -6.712  1.000 39.057 0 821  HOH A O    1 ? 
HETATM 7855 O O    . HOH M 8 .   ? 9.880   -6.722  -19.594 1.000 25.889 0 822  HOH A O    1 ? 
HETATM 7856 O O    . HOH M 8 .   ? 27.203  5.339   15.447  1.000 34.112 0 823  HOH A O    1 ? 
HETATM 7857 O O    . HOH M 8 .   ? 0.391   11.612  -10.733 1.000 30.376 0 824  HOH A O    1 ? 
HETATM 7858 O O    . HOH M 8 .   ? 8.717   12.707  -12.675 1.000 20.045 0 825  HOH A O    1 ? 
HETATM 7859 O O    . HOH M 8 .   ? 10.379  16.053  -10.442 1.000 21.988 0 826  HOH A O    1 ? 
HETATM 7860 O O    . HOH M 8 .   ? 0.722   10.336  -5.556  1.000 27.605 0 827  HOH A O    1 ? 
HETATM 7861 O O    . HOH M 8 .   ? -3.459  9.276   -17.387 1.000 43.030 0 828  HOH A O    1 ? 
HETATM 7862 O O    . HOH M 8 .   ? 14.172  44.261  -23.066 1.000 40.013 0 829  HOH A O    1 ? 
HETATM 7863 O O    . HOH M 8 .   ? 25.441  11.882  -24.532 1.000 33.902 0 830  HOH A O    1 ? 
HETATM 7864 O O    . HOH M 8 .   ? 15.499  4.552   14.083  1.000 27.120 0 831  HOH A O    1 ? 
HETATM 7865 O O    . HOH M 8 .   ? 16.963  38.668  -16.355 1.000 20.300 0 832  HOH A O    1 ? 
HETATM 7866 O O    . HOH M 8 .   ? 24.509  43.097  -21.859 1.000 31.034 0 833  HOH A O    1 ? 
HETATM 7867 O O    . HOH M 8 .   ? 24.849  1.040   17.200  1.000 41.306 0 834  HOH A O    1 ? 
HETATM 7868 O O    . HOH M 8 .   ? 7.690   -14.845 5.599   1.000 33.168 0 835  HOH A O    1 ? 
HETATM 7869 O O    . HOH M 8 .   ? 25.178  14.252  -24.932 1.000 38.583 0 836  HOH A O    1 ? 
HETATM 7870 O O    . HOH M 8 .   ? 24.953  21.507  -22.361 1.000 26.614 0 837  HOH A O    1 ? 
HETATM 7871 O O    . HOH M 8 .   ? 25.571  -10.775 -1.742  1.000 32.443 0 838  HOH A O    1 ? 
HETATM 7872 O O    . HOH M 8 .   ? 10.218  40.285  -37.359 1.000 33.591 0 839  HOH A O    1 ? 
HETATM 7873 O O    . HOH M 8 .   ? 6.397   5.576   -5.976  1.000 18.300 0 840  HOH A O    1 ? 
HETATM 7874 O O    . HOH M 8 .   ? -11.140 -8.254  -13.124 1.000 27.473 0 841  HOH A O    1 ? 
HETATM 7875 O O    . HOH M 8 .   ? 20.481  17.933  -11.863 1.000 19.079 0 842  HOH A O    1 ? 
HETATM 7876 O O    . HOH M 8 .   ? 22.189  -9.151  -12.306 1.000 29.875 0 843  HOH A O    1 ? 
HETATM 7877 O O    . HOH M 8 .   ? -3.173  15.444  -29.726 1.000 36.601 0 844  HOH A O    1 ? 
HETATM 7878 O O    . HOH M 8 .   ? 19.152  11.609  -16.767 1.000 23.144 0 845  HOH A O    1 ? 
HETATM 7879 O O    . HOH M 8 .   ? 1.807   15.983  -16.152 1.000 19.183 0 846  HOH A O    1 ? 
HETATM 7880 O O    . HOH M 8 .   ? -2.326  41.670  -35.746 1.000 27.517 0 847  HOH A O    1 ? 
HETATM 7881 O O    . HOH M 8 .   ? 20.492  17.725  4.782   1.000 41.315 0 848  HOH A O    1 ? 
HETATM 7882 O O    . HOH M 8 .   ? 31.658  35.771  -24.313 1.000 34.514 0 849  HOH A O    1 ? 
HETATM 7883 O O    . HOH M 8 .   ? -6.554  -2.584  4.211   1.000 42.233 0 850  HOH A O    1 ? 
HETATM 7884 O O    . HOH M 8 .   ? 16.468  43.357  -19.849 1.000 32.489 0 851  HOH A O    1 ? 
HETATM 7885 O O    . HOH M 8 .   ? 14.330  29.695  -39.745 1.000 26.480 0 852  HOH A O    1 ? 
HETATM 7886 O O    . HOH M 8 .   ? 18.088  -0.634  -17.706 1.000 22.168 0 853  HOH A O    1 ? 
HETATM 7887 O O    . HOH M 8 .   ? 5.945   11.498  -19.536 1.000 16.358 0 854  HOH A O    1 ? 
HETATM 7888 O O    . HOH M 8 .   ? 15.384  10.071  -7.342  1.000 31.610 0 855  HOH A O    1 ? 
HETATM 7889 O O    . HOH M 8 .   ? 9.778   42.874  -19.969 1.000 26.763 0 856  HOH A O    1 ? 
HETATM 7890 O O    . HOH M 8 .   ? 21.117  13.225  -17.787 1.000 17.069 0 857  HOH A O    1 ? 
HETATM 7891 O O    . HOH M 8 .   ? 24.595  -8.558  -14.977 1.000 41.916 0 858  HOH A O    1 ? 
HETATM 7892 O O    . HOH M 8 .   ? 9.342   4.139   4.711   1.000 20.730 0 859  HOH A O    1 ? 
HETATM 7893 O O    . HOH M 8 .   ? 15.597  26.570  -33.346 1.000 39.652 0 860  HOH A O    1 ? 
HETATM 7894 O O    . HOH M 8 .   ? 20.283  2.227   15.330  1.000 33.019 0 861  HOH A O    1 ? 
HETATM 7895 O O    . HOH M 8 .   ? 19.515  -15.588 9.009   1.000 34.007 0 862  HOH A O    1 ? 
HETATM 7896 O O    . HOH M 8 .   ? 4.574   -14.277 -24.825 1.000 41.368 0 863  HOH A O    1 ? 
HETATM 7897 O O    . HOH M 8 .   ? 13.719  9.713   -18.955 1.000 15.712 0 864  HOH A O    1 ? 
HETATM 7898 O O    . HOH M 8 .   ? -1.561  14.205  -21.481 1.000 26.350 0 865  HOH A O    1 ? 
HETATM 7899 O O    . HOH M 8 .   ? 8.490   15.366  -12.187 1.000 24.228 0 866  HOH A O    1 ? 
HETATM 7900 O O    . HOH M 8 .   ? 18.391  -5.281  -17.325 1.000 37.470 0 867  HOH A O    1 ? 
HETATM 7901 O O    . HOH M 8 .   ? 24.626  33.800  -13.649 1.000 28.770 0 868  HOH A O    1 ? 
HETATM 7902 O O    . HOH M 8 .   ? 24.681  -9.500  -8.274  1.000 34.247 0 869  HOH A O    1 ? 
HETATM 7903 O O    . HOH M 8 .   ? 22.339  -3.960  -19.960 1.000 43.229 0 870  HOH A O    1 ? 
HETATM 7904 O O    . HOH M 8 .   ? 13.157  9.837   -8.618  1.000 32.825 0 871  HOH A O    1 ? 
HETATM 7905 O O    . HOH M 8 .   ? 21.832  42.762  -12.976 1.000 34.319 0 872  HOH A O    1 ? 
HETATM 7906 O O    . HOH M 8 .   ? 2.655   4.847   5.561   1.000 25.282 0 873  HOH A O    1 ? 
HETATM 7907 O O    . HOH M 8 .   ? 19.837  36.266  -39.757 1.000 53.977 0 874  HOH A O    1 ? 
HETATM 7908 O O    . HOH M 8 .   ? 27.634  19.395  -20.853 1.000 27.499 0 875  HOH A O    1 ? 
HETATM 7909 O O    . HOH M 8 .   ? -6.885  -11.266 1.395   1.000 46.199 0 876  HOH A O    1 ? 
HETATM 7910 O O    . HOH M 8 .   ? -1.229  31.896  -30.312 1.000 31.225 0 877  HOH A O    1 ? 
HETATM 7911 O O    . HOH M 8 .   ? 20.538  -13.893 0.497   1.000 36.901 0 878  HOH A O    1 ? 
HETATM 7912 O O    . HOH M 8 .   ? 12.899  38.680  -13.619 1.000 41.457 0 879  HOH A O    1 ? 
HETATM 7913 O O    . HOH M 8 .   ? 25.432  1.609   7.732   1.000 24.628 0 880  HOH A O    1 ? 
HETATM 7914 O O    . HOH M 8 .   ? 22.818  -0.006  14.732  1.000 32.890 0 881  HOH A O    1 ? 
HETATM 7915 O O    . HOH M 8 .   ? 7.024   -7.114  11.236  1.000 27.617 0 882  HOH A O    1 ? 
HETATM 7916 O O    . HOH M 8 .   ? 4.594   -0.015  -3.602  1.000 20.680 0 883  HOH A O    1 ? 
HETATM 7917 O O    . HOH M 8 .   ? 3.744   3.612   7.777   1.000 26.374 0 884  HOH A O    1 ? 
HETATM 7918 O O    . HOH M 8 .   ? 15.897  4.627   -30.014 1.000 25.318 0 885  HOH A O    1 ? 
HETATM 7919 O O    . HOH M 8 .   ? 18.068  -3.166  -18.829 1.000 40.940 0 886  HOH A O    1 ? 
HETATM 7920 O O    . HOH M 8 .   ? -6.315  9.305   -12.934 1.000 27.975 0 887  HOH A O    1 ? 
HETATM 7921 O O    . HOH M 8 .   ? 17.971  10.144  16.495  1.000 43.441 0 888  HOH A O    1 ? 
HETATM 7922 O O    . HOH M 8 .   ? -4.630  6.656   -22.945 1.000 33.196 0 889  HOH A O    1 ? 
HETATM 7923 O O    . HOH M 8 .   ? 1.947   47.065  -25.071 1.000 50.938 0 890  HOH A O    1 ? 
HETATM 7924 O O    . HOH M 8 .   ? 31.671  2.498   -6.080  1.000 30.731 0 891  HOH A O    1 ? 
HETATM 7925 O O    . HOH M 8 .   ? 12.525  11.335  13.980  1.000 44.603 0 892  HOH A O    1 ? 
HETATM 7926 O O    . HOH M 8 .   ? 21.809  11.799  8.459   1.000 24.890 0 893  HOH A O    1 ? 
HETATM 7927 O O    . HOH M 8 .   ? 9.518   19.053  -10.487 1.000 28.693 0 894  HOH A O    1 ? 
HETATM 7928 O O    . HOH M 8 .   ? 24.079  -0.052  -16.146 1.000 17.402 0 895  HOH A O    1 ? 
HETATM 7929 O O    . HOH M 8 .   ? 2.357   37.595  -37.353 1.000 26.362 0 896  HOH A O    1 ? 
HETATM 7930 O O    . HOH M 8 .   ? -2.053  36.219  -23.099 1.000 31.765 0 897  HOH A O    1 ? 
HETATM 7931 O O    . HOH M 8 .   ? 5.360   14.312  3.392   1.000 44.765 0 898  HOH A O    1 ? 
HETATM 7932 O O    . HOH M 8 .   ? 11.481  35.809  -12.535 1.000 35.038 0 899  HOH A O    1 ? 
HETATM 7933 O O    . HOH M 8 .   ? 31.225  48.908  -13.751 1.000 40.401 0 900  HOH A O    1 ? 
HETATM 7934 O O    . HOH M 8 .   ? 12.313  -0.116  -22.013 1.000 27.293 0 901  HOH A O    1 ? 
HETATM 7935 O O    . HOH M 8 .   ? 18.536  11.797  14.506  1.000 36.311 0 902  HOH A O    1 ? 
HETATM 7936 O O    . HOH M 8 .   ? 25.727  10.468  2.378   1.000 31.333 0 903  HOH A O    1 ? 
HETATM 7937 O O    . HOH M 8 .   ? 11.989  3.280   0.424   1.000 20.660 0 904  HOH A O    1 ? 
HETATM 7938 O O    . HOH M 8 .   ? 1.664   14.178  -11.898 1.000 35.571 0 905  HOH A O    1 ? 
HETATM 7939 O O    . HOH M 8 .   ? 7.700   33.650  -12.946 1.000 32.912 0 906  HOH A O    1 ? 
HETATM 7940 O O    . HOH M 8 .   ? 34.445  11.118  -15.712 1.000 40.769 0 907  HOH A O    1 ? 
HETATM 7941 O O    . HOH M 8 .   ? 29.148  21.071  -8.136  1.000 41.532 0 908  HOH A O    1 ? 
HETATM 7942 O O    . HOH M 8 .   ? 30.436  8.812   -2.358  1.000 30.556 0 909  HOH A O    1 ? 
HETATM 7943 O O    . HOH M 8 .   ? 29.273  10.024  -21.065 1.000 32.092 0 910  HOH A O    1 ? 
HETATM 7944 O O    . HOH M 8 .   ? 17.827  -11.827 11.542  1.000 33.781 0 911  HOH A O    1 ? 
HETATM 7945 O O    . HOH M 8 .   ? 14.288  7.449   -17.461 1.000 16.658 0 912  HOH A O    1 ? 
HETATM 7946 O O    . HOH M 8 .   ? 21.278  26.861  -30.408 1.000 36.013 0 913  HOH A O    1 ? 
HETATM 7947 O O    . HOH M 8 .   ? 25.473  11.718  -2.187  1.000 25.646 0 914  HOH A O    1 ? 
HETATM 7948 O O    . HOH M 8 .   ? 23.912  23.374  -29.831 1.000 46.512 0 915  HOH A O    1 ? 
HETATM 7949 O O    . HOH M 8 .   ? 6.479   25.063  -40.806 1.000 32.589 0 916  HOH A O    1 ? 
HETATM 7950 O O    . HOH M 8 .   ? -3.224  46.987  -25.509 1.000 44.886 0 917  HOH A O    1 ? 
HETATM 7951 O O    . HOH M 8 .   ? -3.944  14.198  -1.552  1.000 52.648 0 918  HOH A O    1 ? 
HETATM 7952 O O    . HOH M 8 .   ? -2.409  -3.425  3.352   1.000 30.647 0 919  HOH A O    1 ? 
HETATM 7953 O O    . HOH M 8 .   ? 29.044  5.303   -3.650  1.000 23.091 0 920  HOH A O    1 ? 
HETATM 7954 O O    . HOH M 8 .   ? -2.036  -0.646  9.369   1.000 38.635 0 921  HOH A O    1 ? 
HETATM 7955 O O    . HOH M 8 .   ? 34.807  11.802  -10.852 1.000 46.795 0 922  HOH A O    1 ? 
HETATM 7956 O O    . HOH M 8 .   ? 24.630  44.825  -9.781  1.000 37.876 0 923  HOH A O    1 ? 
HETATM 7957 O O    . HOH M 8 .   ? 20.705  13.996  8.534   1.000 41.412 0 924  HOH A O    1 ? 
HETATM 7958 O O    . HOH M 8 .   ? 18.988  -13.923 -1.863  1.000 39.506 0 925  HOH A O    1 ? 
HETATM 7959 O O    . HOH M 8 .   ? 5.380   6.904   5.829   1.000 42.420 0 926  HOH A O    1 ? 
HETATM 7960 O O    . HOH M 8 .   ? 24.087  3.923   8.716   1.000 26.727 0 927  HOH A O    1 ? 
HETATM 7961 O O    . HOH M 8 .   ? -1.526  33.606  -26.188 1.000 45.517 0 928  HOH A O    1 ? 
HETATM 7962 O O    . HOH M 8 .   ? 24.861  47.520  -34.337 1.000 39.610 0 929  HOH A O    1 ? 
HETATM 7963 O O    . HOH M 8 .   ? 14.988  -12.691 13.586  1.000 34.039 0 930  HOH A O    1 ? 
HETATM 7964 O O    . HOH M 8 .   ? 11.616  2.412   -2.223  1.000 18.310 0 931  HOH A O    1 ? 
HETATM 7965 O O    . HOH M 8 .   ? -2.167  -8.653  7.224   1.000 46.772 0 932  HOH A O    1 ? 
HETATM 7966 O O    . HOH M 8 .   ? 5.915   -18.692 -12.418 1.000 48.402 0 933  HOH A O    1 ? 
HETATM 7967 O O    . HOH M 8 .   ? -6.377  40.817  -29.605 1.000 34.503 0 934  HOH A O    1 ? 
HETATM 7968 O O    . HOH M 8 .   ? 31.217  16.692  -13.557 1.000 27.904 0 935  HOH A O    1 ? 
HETATM 7969 O O    . HOH M 8 .   ? 15.622  22.281  -32.883 1.000 40.096 0 936  HOH A O    1 ? 
HETATM 7970 O O    . HOH M 8 .   ? 10.054  47.502  -34.653 1.000 30.621 0 937  HOH A O    1 ? 
HETATM 7971 O O    . HOH M 8 .   ? 28.133  -4.374  0.379   1.000 39.127 0 938  HOH A O    1 ? 
HETATM 7972 O O    . HOH M 8 .   ? 8.468   9.463   -1.170  1.000 19.701 0 939  HOH A O    1 ? 
HETATM 7973 O O    . HOH M 8 .   ? 22.157  13.044  -31.703 1.000 50.309 0 940  HOH A O    1 ? 
HETATM 7974 O O    . HOH M 8 .   ? -11.584 -0.827  -7.239  1.000 47.073 0 941  HOH A O    1 ? 
HETATM 7975 O O    . HOH M 8 .   ? 18.330  -1.256  15.446  1.000 32.799 0 942  HOH A O    1 ? 
HETATM 7976 O O    . HOH M 8 .   ? 20.826  16.428  -28.447 1.000 40.002 0 943  HOH A O    1 ? 
HETATM 7977 O O    . HOH M 8 .   ? 7.147   48.560  -27.501 1.000 34.767 0 944  HOH A O    1 ? 
HETATM 7978 O O    . HOH M 8 .   ? 27.758  -0.009  5.855   1.000 26.028 0 945  HOH A O    1 ? 
HETATM 7979 O O    . HOH M 8 .   ? 32.592  3.077   -13.065 1.000 28.606 0 946  HOH A O    1 ? 
HETATM 7980 O O    . HOH M 8 .   ? 11.548  -5.288  -21.206 1.000 44.771 0 947  HOH A O    1 ? 
HETATM 7981 O O    . HOH M 8 .   ? 16.915  16.002  -29.931 1.000 32.145 0 948  HOH A O    1 ? 
HETATM 7982 O O    . HOH M 8 .   ? 28.363  33.236  -10.299 1.000 45.336 0 949  HOH A O    1 ? 
HETATM 7983 O O    . HOH M 8 .   ? 17.368  32.514  -45.817 1.000 55.732 0 950  HOH A O    1 ? 
HETATM 7984 O O    . HOH M 8 .   ? 27.175  44.735  -10.584 1.000 28.743 0 951  HOH A O    1 ? 
HETATM 7985 O O    . HOH M 8 .   ? 16.707  -21.713 -0.775  1.000 36.650 0 952  HOH A O    1 ? 
HETATM 7986 O O    . HOH M 8 .   ? -10.939 -7.751  -20.079 1.000 36.103 0 953  HOH A O    1 ? 
HETATM 7987 O O    . HOH M 8 .   ? -5.057  -15.114 -16.705 1.000 32.171 0 954  HOH A O    1 ? 
HETATM 7988 O O    . HOH M 8 .   ? 15.307  10.179  -4.856  1.000 35.790 0 955  HOH A O    1 ? 
HETATM 7989 O O    . HOH M 8 .   ? 3.213   23.345  -8.358  1.000 50.622 0 956  HOH A O    1 ? 
HETATM 7990 O O    . HOH M 8 .   ? 21.004  44.052  -18.294 1.000 32.572 0 957  HOH A O    1 ? 
HETATM 7991 O O    . HOH M 8 .   ? 12.618  10.380  -32.900 1.000 40.608 0 958  HOH A O    1 ? 
HETATM 7992 O O    . HOH M 8 .   ? -8.628  -5.529  -1.074  1.000 44.828 0 959  HOH A O    1 ? 
HETATM 7993 O O    . HOH M 8 .   ? 2.912   9.901   -11.244 1.000 38.019 0 960  HOH A O    1 ? 
HETATM 7994 O O    . HOH M 8 .   ? 19.798  -3.877  -21.365 1.000 45.689 0 961  HOH A O    1 ? 
HETATM 7995 O O    . HOH M 8 .   ? 9.783   14.682  -0.337  1.000 40.714 0 962  HOH A O    1 ? 
HETATM 7996 O O    . HOH M 8 .   ? 12.300  9.515   -4.937  1.000 28.316 0 963  HOH A O    1 ? 
HETATM 7997 O O    . HOH M 8 .   ? 12.208  -9.773  -16.268 1.000 28.743 0 964  HOH A O    1 ? 
HETATM 7998 O O    . HOH M 8 .   ? 31.548  15.664  -7.895  1.000 39.152 0 965  HOH A O    1 ? 
HETATM 7999 O O    . HOH M 8 .   ? 14.430  12.421  -32.139 1.000 42.657 0 966  HOH A O    1 ? 
HETATM 8000 O O    . HOH M 8 .   ? 21.305  47.059  -27.226 1.000 43.757 0 967  HOH A O    1 ? 
HETATM 8001 O O    . HOH M 8 .   ? -10.400 3.164   -2.679  1.000 62.821 0 968  HOH A O    1 ? 
HETATM 8002 O O    . HOH M 8 .   ? 17.686  17.554  -28.138 1.000 33.144 0 969  HOH A O    1 ? 
HETATM 8003 O O    . HOH M 8 .   ? 29.786  39.270  -29.470 1.000 38.114 0 970  HOH A O    1 ? 
HETATM 8004 O O    . HOH M 8 .   ? -5.984  -2.998  -14.308 1.000 35.364 0 971  HOH A O    1 ? 
HETATM 8005 O O    . HOH M 8 .   ? 27.905  43.356  -24.795 1.000 32.213 0 972  HOH A O    1 ? 
HETATM 8006 O O    . HOH M 8 .   ? 30.418  18.015  -9.490  1.000 44.230 0 973  HOH A O    1 ? 
HETATM 8007 O O    . HOH M 8 .   ? -5.830  16.943  -24.562 1.000 40.742 0 974  HOH A O    1 ? 
HETATM 8008 O O    . HOH M 8 .   ? -6.060  13.998  2.736   1.000 61.035 0 975  HOH A O    1 ? 
HETATM 8009 O O    . HOH M 8 .   ? 18.505  30.511  -10.997 1.000 46.567 0 976  HOH A O    1 ? 
HETATM 8010 O O    . HOH M 8 .   ? 14.573  -9.588  -15.565 1.000 43.557 0 977  HOH A O    1 ? 
HETATM 8011 O O    . HOH M 8 .   ? -12.501 1.095   -7.666  1.000 53.029 0 978  HOH A O    1 ? 
HETATM 8012 O O    . HOH M 8 .   ? 30.333  31.717  -23.165 1.000 40.328 0 979  HOH A O    1 ? 
HETATM 8013 O O    . HOH M 8 .   ? 31.377  22.080  -14.110 1.000 39.755 0 980  HOH A O    1 ? 
HETATM 8014 O O    . HOH M 8 .   ? 4.955   -18.486 -16.037 1.000 42.015 0 981  HOH A O    1 ? 
HETATM 8015 O O    . HOH M 8 .   ? 29.232  -3.920  7.189   1.000 48.057 0 982  HOH A O    1 ? 
HETATM 8016 O O    . HOH M 8 .   ? -7.734  0.285   4.796   1.000 53.407 0 983  HOH A O    1 ? 
HETATM 8017 O O    . HOH M 8 .   ? 11.490  13.492  -32.621 1.000 34.074 0 984  HOH A O    1 ? 
HETATM 8018 O O    . HOH M 8 .   ? 9.560   48.883  -26.315 1.000 43.082 0 985  HOH A O    1 ? 
HETATM 8019 O O    . HOH M 8 .   ? 16.406  49.305  -33.699 1.000 48.138 0 986  HOH A O    1 ? 
HETATM 8020 O O    . HOH M 8 .   ? 23.855  24.918  -36.319 1.000 57.828 0 987  HOH A O    1 ? 
HETATM 8021 O O    . HOH M 8 .   ? 28.982  50.406  -13.865 1.000 41.492 0 988  HOH A O    1 ? 
HETATM 8022 O O    . HOH M 8 .   ? 18.706  44.741  -19.630 1.000 50.365 0 989  HOH A O    1 ? 
HETATM 8023 O O    . HOH M 8 .   ? 1.683   -16.106 3.870   1.000 49.802 0 990  HOH A O    1 ? 
HETATM 8024 O O    . HOH M 8 .   ? 12.583  46.315  -24.388 1.000 42.024 0 991  HOH A O    1 ? 
HETATM 8025 O O    . HOH M 8 .   ? 11.274  -9.057  -19.036 1.000 32.171 0 992  HOH A O    1 ? 
HETATM 8026 O O    . HOH M 8 .   ? 5.375   -16.019 2.852   1.000 48.138 0 993  HOH A O    1 ? 
HETATM 8027 O O    . HOH M 8 .   ? -3.067  1.380   8.671   1.000 41.010 0 994  HOH A O    1 ? 
HETATM 8028 O O    . HOH M 8 .   ? -6.540  38.203  -29.659 1.000 58.196 0 995  HOH A O    1 ? 
HETATM 8029 O O    . HOH M 8 .   ? 17.752  44.123  -13.131 1.000 46.591 0 996  HOH A O    1 ? 
HETATM 8030 O O    . HOH M 8 .   ? -10.789 -6.440  -2.954  1.000 44.259 0 997  HOH A O    1 ? 
HETATM 8031 O O    . HOH M 8 .   ? 0.019   11.994  -8.048  1.000 48.072 0 998  HOH A O    1 ? 
HETATM 8032 O O    . HOH M 8 .   ? 19.036  24.905  -35.199 1.000 43.022 0 999  HOH A O    1 ? 
HETATM 8033 O O    . HOH M 8 .   ? 17.714  47.938  -36.026 1.000 58.328 0 1000 HOH A O    1 ? 
HETATM 8034 O O    . HOH M 8 .   ? -5.510  9.283   -23.098 1.000 43.222 0 1001 HOH A O    1 ? 
HETATM 8035 O O    . HOH M 8 .   ? 3.897   -2.819  -26.416 1.000 27.140 0 1002 HOH A O    1 ? 
HETATM 8036 O O    . HOH M 8 .   ? 26.147  -2.518  -21.779 1.000 48.921 0 1003 HOH A O    1 ? 
HETATM 8037 O O    . HOH M 8 .   ? 6.785   -14.688 9.697   1.000 47.359 0 1004 HOH A O    1 ? 
HETATM 8038 O O    . HOH M 8 .   ? 11.092  -14.240 -6.539  1.000 44.008 0 1005 HOH A O    1 ? 
HETATM 8039 O O    . HOH M 8 .   ? 23.501  49.851  -35.049 1.000 44.667 0 1006 HOH A O    1 ? 
HETATM 8040 O O    . HOH M 8 .   ? 35.058  41.656  -21.845 1.000 55.150 0 1007 HOH A O    1 ? 
HETATM 8041 O O    . HOH M 8 .   ? 9.804   -16.428 5.568   1.000 47.266 0 1008 HOH A O    1 ? 
HETATM 8042 O O    . HOH M 8 .   ? 1.686   -11.505 -32.340 1.000 50.744 0 1009 HOH A O    1 ? 
HETATM 8043 O O    . HOH M 8 .   ? -19.685 6.037   -1.097  1.000 46.704 0 1010 HOH A O    1 ? 
HETATM 8044 O O    . HOH M 8 .   ? 25.690  8.295   7.006   1.000 42.521 0 1011 HOH A O    1 ? 
HETATM 8045 O O    . HOH M 8 .   ? -11.506 -2.533  -16.336 1.000 49.226 0 1012 HOH A O    1 ? 
HETATM 8046 O O    . HOH M 8 .   ? -3.494  -7.205  12.521  1.000 53.931 0 1013 HOH A O    1 ? 
HETATM 8047 O O    . HOH M 8 .   ? 23.733  15.507  -30.195 1.000 58.226 0 1014 HOH A O    1 ? 
HETATM 8048 O O    . HOH M 8 .   ? 27.878  8.780   -22.905 1.000 44.245 0 1015 HOH A O    1 ? 
HETATM 8049 O O    . HOH M 8 .   ? 15.298  44.238  -16.960 1.000 46.308 0 1016 HOH A O    1 ? 
HETATM 8050 O O    . HOH M 8 .   ? 19.741  13.163  -5.530  1.000 35.278 0 1017 HOH A O    1 ? 
HETATM 8051 O O    . HOH M 8 .   ? 8.776   -8.997  -23.509 1.000 54.020 0 1018 HOH A O    1 ? 
HETATM 8052 O O    . HOH M 8 .   ? 25.952  -11.906 -4.048  1.000 46.812 0 1019 HOH A O    1 ? 
HETATM 8053 O O    . HOH M 8 .   ? 23.932  11.623  10.255  1.000 32.990 0 1020 HOH A O    1 ? 
HETATM 8054 O O    . HOH M 8 .   ? 11.566  0.037   -24.719 1.000 44.884 0 1021 HOH A O    1 ? 
HETATM 8055 O O    . HOH M 8 .   ? 0.497   -12.963 8.153   1.000 44.692 0 1022 HOH A O    1 ? 
HETATM 8056 O O    . HOH M 8 .   ? 25.466  9.705   9.194   1.000 34.891 0 1023 HOH A O    1 ? 
HETATM 8057 O O    . HOH M 8 .   ? 24.608  -10.717 -10.747 1.000 43.822 0 1024 HOH A O    1 ? 
HETATM 8058 O O    . HOH M 8 .   ? 12.206  44.146  -19.911 1.000 40.249 0 1025 HOH A O    1 ? 
HETATM 8059 O O    . HOH M 8 .   ? 27.618  -3.196  11.446  1.000 53.553 0 1026 HOH A O    1 ? 
HETATM 8060 O O    . HOH M 8 .   ? 11.551  -15.530 10.488  1.000 58.297 0 1027 HOH A O    1 ? 
HETATM 8061 O O    . HOH M 8 .   ? 18.157  -14.645 11.333  1.000 38.459 0 1028 HOH A O    1 ? 
HETATM 8062 O O    . HOH M 8 .   ? 19.877  18.051  -6.828  1.000 50.468 0 1029 HOH A O    1 ? 
HETATM 8063 O O    . HOH M 8 .   ? 19.254  14.371  11.167  1.000 52.164 0 1030 HOH A O    1 ? 
HETATM 8064 O O    . HOH M 8 .   ? -10.918 -6.438  -17.738 1.000 40.677 0 1031 HOH A O    1 ? 
HETATM 8065 O O    . HOH M 8 .   ? 7.302   13.188  -2.557  1.000 39.849 0 1032 HOH A O    1 ? 
HETATM 8066 O O    . HOH M 8 .   ? 25.834  7.259   10.403  1.000 33.254 0 1033 HOH A O    1 ? 
HETATM 8067 O O    . HOH M 8 .   ? 31.446  21.812  -18.162 1.000 52.339 0 1034 HOH A O    1 ? 
HETATM 8068 O O    . HOH M 8 .   ? 17.390  2.440   14.887  1.000 40.663 0 1035 HOH A O    1 ? 
HETATM 8069 O O    . HOH M 8 .   ? 12.383  46.495  -34.013 1.000 37.653 0 1036 HOH A O    1 ? 
HETATM 8070 O O    . HOH M 8 .   ? 9.123   1.017   -5.381  1.000 16.922 0 1037 HOH A O    1 ? 
HETATM 8071 O O    . HOH M 8 .   ? 19.365  -7.538  -19.911 1.000 48.292 0 1038 HOH A O    1 ? 
HETATM 8072 O O    . HOH M 8 .   ? 11.006  -13.413 -17.428 1.000 50.211 0 1039 HOH A O    1 ? 
HETATM 8073 O O    . HOH M 8 .   ? 31.484  37.213  -30.569 1.000 38.267 0 1040 HOH A O    1 ? 
HETATM 8074 O O    . HOH M 8 .   ? 6.854   -16.501 7.996   1.000 49.803 0 1041 HOH A O    1 ? 
HETATM 8075 O O    . HOH M 8 .   ? 7.989   11.905  -7.981  1.000 58.328 0 1042 HOH A O    1 ? 
HETATM 8076 O O    . HOH M 8 .   ? 5.234   7.146   12.429  1.000 36.689 0 1043 HOH A O    1 ? 
HETATM 8077 O O    . HOH M 8 .   ? -3.310  30.866  -21.991 1.000 50.551 0 1044 HOH A O    1 ? 
HETATM 8078 O O    . HOH M 8 .   ? 7.523   12.020  7.388   1.000 47.763 0 1045 HOH A O    1 ? 
HETATM 8079 O O    . HOH M 8 .   ? 30.768  3.631   11.634  1.000 52.558 0 1046 HOH A O    1 ? 
HETATM 8080 O O    . HOH M 8 .   ? 26.006  5.850   7.925   1.000 37.783 0 1047 HOH A O    1 ? 
HETATM 8081 O O    . HOH M 8 .   ? 29.888  5.045   7.951   1.000 46.288 0 1048 HOH A O    1 ? 
HETATM 8082 O O    . HOH M 8 .   ? 17.416  16.333  -32.339 1.000 39.174 0 1049 HOH A O    1 ? 
HETATM 8083 O O    . HOH M 8 .   ? 28.415  -5.818  -9.052  1.000 52.656 0 1050 HOH A O    1 ? 
HETATM 8084 O O    . HOH M 8 .   ? 7.552   -7.132  -21.045 1.000 30.719 0 1051 HOH A O    1 ? 
HETATM 8085 O O    . HOH M 8 .   ? 8.717   21.469  -8.407  1.000 48.046 0 1052 HOH A O    1 ? 
HETATM 8086 O O    . HOH M 8 .   ? 9.683   15.708  3.010   1.000 49.317 0 1053 HOH A O    1 ? 
HETATM 8087 O O    . HOH M 8 .   ? 4.321   -14.109 10.332  1.000 41.796 0 1054 HOH A O    1 ? 
HETATM 8088 O O    . HOH M 8 .   ? -2.217  -24.577 -16.587 1.000 55.078 0 1055 HOH A O    1 ? 
HETATM 8089 O O    . HOH M 8 .   ? 33.403  13.915  -9.057  1.000 37.424 0 1056 HOH A O    1 ? 
HETATM 8090 O O    . HOH M 8 .   ? 25.716  12.438  0.618   1.000 29.470 0 1057 HOH A O    1 ? 
HETATM 8091 O O    . HOH M 8 .   ? 27.555  15.141  3.790   1.000 52.701 0 1058 HOH A O    1 ? 
HETATM 8092 O O    . HOH M 8 .   ? 29.028  -0.757  -2.388  1.000 36.706 0 1059 HOH A O    1 ? 
HETATM 8093 O O    . HOH M 8 .   ? 31.679  2.563   -2.183  1.000 40.643 0 1060 HOH A O    1 ? 
HETATM 8094 O O    . HOH M 8 .   ? 24.209  -15.032 -2.978  1.000 51.344 0 1061 HOH A O    1 ? 
HETATM 8095 O O    . HOH M 8 .   ? 13.976  13.699  -6.253  1.000 54.055 0 1062 HOH A O    1 ? 
HETATM 8096 O O    . HOH M 8 .   ? 29.812  2.551   -4.135  1.000 27.424 0 1063 HOH A O    1 ? 
HETATM 8097 O O    . HOH M 8 .   ? 25.451  15.064  1.616   1.000 39.667 0 1064 HOH A O    1 ? 
HETATM 8098 O O    . HOH M 8 .   ? 14.924  19.770  -8.128  1.000 42.770 0 1065 HOH A O    1 ? 
HETATM 8099 O O    . HOH M 8 .   ? 5.207   34.550  -13.321 1.000 39.786 0 1066 HOH A O    1 ? 
HETATM 8100 O O    . HOH M 8 .   ? 15.783  24.800  -52.226 1.000 62.005 0 1067 HOH A O    1 ? 
HETATM 8101 O O    . HOH M 8 .   ? 28.752  -6.654  -4.878  1.000 55.255 0 1068 HOH A O    1 ? 
HETATM 8102 O O    . HOH M 8 .   ? 28.607  -9.701  -11.320 1.000 55.801 0 1069 HOH A O    1 ? 
HETATM 8103 O O    . HOH M 8 .   ? 5.784   -17.527 12.957  1.000 57.408 0 1070 HOH A O    1 ? 
# 
