data_8VA5
# 
_entry.id   8VA5 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.399 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8VA5         pdb_00008va5 10.2210/pdb8va5/pdb 
WWPDB D_1000279498 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2024-11-20 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8VA5 
_pdbx_database_status.recvd_initial_deposition_date   2023-12-11 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
loop_
_pdbx_contact_author.id 
_pdbx_contact_author.email 
_pdbx_contact_author.name_first 
_pdbx_contact_author.name_last 
_pdbx_contact_author.name_mi 
_pdbx_contact_author.role 
_pdbx_contact_author.identifier_ORCID 
4 tomaszc@umich.edu  Tomasz  Cierpicki ? 'principal investigator/group leader' 0000-0003-2058-0658 
5 jolantag@umich.edu Jolanta Grembecka ? 'principal investigator/group leader' 0000-0002-6180-9095 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Clegg, B.D.'   1 0000-0001-6651-3878 
'Cierpicki, T.' 2 0000-0003-2058-0658 
'Grembecka, J.' 3 0000-0002-6180-9095 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'Menin mutant - T349M in complex with Ziftomenib (KO-539)' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Clegg, B.D.'   1 0000-0001-6651-3878 
primary 'Cierpicki, T.' 2 0000-0003-2058-0658 
primary 'Grembecka, J.' 3 0000-0002-6180-9095 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man Menin                   54630.340 1   ? T349M ? ? 
2 non-polymer syn Ziftomenib              717.871   1   ? ?     ? ? 
3 non-polymer syn 'DI(HYDROXYETHYL)ETHER' 106.120   2   ? ?     ? ? 
4 non-polymer syn 'TETRAETHYLENE GLYCOL'  194.226   1   ? ?     ? ? 
5 non-polymer syn 1,2-ETHANEDIOL          62.068    1   ? ?     ? ? 
6 non-polymer syn 'DIMETHYL SULFOXIDE'    78.133    2   ? ?     ? ? 
7 water       nat water                   18.015    634 ? ?     ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;GGSSSMGLKAAQKTLFPLRSIDDVVRLFAAELGREEPDLVLLSLVLGFVEHFLAVNRVGLTYFPVADLSIIAALYARFTA
QIRGAVDLSLYPREGGVSSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFITGTKLDSSGVAFAVVGACQALGLRDVHL
ALSEDHAWVVFGPNGEQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLKGSYMRCDRKMEVAFMVCAINPSIDLHTDSLE
LLQLQQKLLWLLYDLGHLERYPMALGNLADLEELEPTPGRPDPLTLYHKGIASAKTYYRDEHIYPYMYLAGYHCRNRNVR
EALQAWADMATVIQDYNYCREDEEIYKEFFEVANDVIPNLLKEAASLLEAGSQGSALQDPECFAHLLRFYDGICKWEEGS
PTPVLHVGWATFLVQSLGRFEGQVRQKVRIVSVPAPTASPPPEGPVLTFQSEKMKGMKELLVATKINSSAIKLQLTAQSQ
VQMKKQKVS
;
_entity_poly.pdbx_seq_one_letter_code_can   
;GGSSSMGLKAAQKTLFPLRSIDDVVRLFAAELGREEPDLVLLSLVLGFVEHFLAVNRVGLTYFPVADLSIIAALYARFTA
QIRGAVDLSLYPREGGVSSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFITGTKLDSSGVAFAVVGACQALGLRDVHL
ALSEDHAWVVFGPNGEQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLKGSYMRCDRKMEVAFMVCAINPSIDLHTDSLE
LLQLQQKLLWLLYDLGHLERYPMALGNLADLEELEPTPGRPDPLTLYHKGIASAKTYYRDEHIYPYMYLAGYHCRNRNVR
EALQAWADMATVIQDYNYCREDEEIYKEFFEVANDVIPNLLKEAASLLEAGSQGSALQDPECFAHLLRFYDGICKWEEGS
PTPVLHVGWATFLVQSLGRFEGQVRQKVRIVSVPAPTASPPPEGPVLTFQSEKMKGMKELLVATKINSSAIKLQLTAQSQ
VQMKKQKVS
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 Ziftomenib              K5O 
3 'DI(HYDROXYETHYL)ETHER' PEG 
4 'TETRAETHYLENE GLYCOL'  PG4 
5 1,2-ETHANEDIOL          EDO 
6 'DIMETHYL SULFOXIDE'    DMS 
7 water                   HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   GLY n 
1 2   GLY n 
1 3   SER n 
1 4   SER n 
1 5   SER n 
1 6   MET n 
1 7   GLY n 
1 8   LEU n 
1 9   LYS n 
1 10  ALA n 
1 11  ALA n 
1 12  GLN n 
1 13  LYS n 
1 14  THR n 
1 15  LEU n 
1 16  PHE n 
1 17  PRO n 
1 18  LEU n 
1 19  ARG n 
1 20  SER n 
1 21  ILE n 
1 22  ASP n 
1 23  ASP n 
1 24  VAL n 
1 25  VAL n 
1 26  ARG n 
1 27  LEU n 
1 28  PHE n 
1 29  ALA n 
1 30  ALA n 
1 31  GLU n 
1 32  LEU n 
1 33  GLY n 
1 34  ARG n 
1 35  GLU n 
1 36  GLU n 
1 37  PRO n 
1 38  ASP n 
1 39  LEU n 
1 40  VAL n 
1 41  LEU n 
1 42  LEU n 
1 43  SER n 
1 44  LEU n 
1 45  VAL n 
1 46  LEU n 
1 47  GLY n 
1 48  PHE n 
1 49  VAL n 
1 50  GLU n 
1 51  HIS n 
1 52  PHE n 
1 53  LEU n 
1 54  ALA n 
1 55  VAL n 
1 56  ASN n 
1 57  ARG n 
1 58  VAL n 
1 59  GLY n 
1 60  LEU n 
1 61  THR n 
1 62  TYR n 
1 63  PHE n 
1 64  PRO n 
1 65  VAL n 
1 66  ALA n 
1 67  ASP n 
1 68  LEU n 
1 69  SER n 
1 70  ILE n 
1 71  ILE n 
1 72  ALA n 
1 73  ALA n 
1 74  LEU n 
1 75  TYR n 
1 76  ALA n 
1 77  ARG n 
1 78  PHE n 
1 79  THR n 
1 80  ALA n 
1 81  GLN n 
1 82  ILE n 
1 83  ARG n 
1 84  GLY n 
1 85  ALA n 
1 86  VAL n 
1 87  ASP n 
1 88  LEU n 
1 89  SER n 
1 90  LEU n 
1 91  TYR n 
1 92  PRO n 
1 93  ARG n 
1 94  GLU n 
1 95  GLY n 
1 96  GLY n 
1 97  VAL n 
1 98  SER n 
1 99  SER n 
1 100 ARG n 
1 101 GLU n 
1 102 LEU n 
1 103 VAL n 
1 104 LYS n 
1 105 LYS n 
1 106 VAL n 
1 107 SER n 
1 108 ASP n 
1 109 VAL n 
1 110 ILE n 
1 111 TRP n 
1 112 ASN n 
1 113 SER n 
1 114 LEU n 
1 115 SER n 
1 116 ARG n 
1 117 SER n 
1 118 TYR n 
1 119 PHE n 
1 120 LYS n 
1 121 ASP n 
1 122 ARG n 
1 123 ALA n 
1 124 HIS n 
1 125 ILE n 
1 126 GLN n 
1 127 SER n 
1 128 LEU n 
1 129 PHE n 
1 130 SER n 
1 131 PHE n 
1 132 ILE n 
1 133 THR n 
1 134 GLY n 
1 135 THR n 
1 136 LYS n 
1 137 LEU n 
1 138 ASP n 
1 139 SER n 
1 140 SER n 
1 141 GLY n 
1 142 VAL n 
1 143 ALA n 
1 144 PHE n 
1 145 ALA n 
1 146 VAL n 
1 147 VAL n 
1 148 GLY n 
1 149 ALA n 
1 150 CYS n 
1 151 GLN n 
1 152 ALA n 
1 153 LEU n 
1 154 GLY n 
1 155 LEU n 
1 156 ARG n 
1 157 ASP n 
1 158 VAL n 
1 159 HIS n 
1 160 LEU n 
1 161 ALA n 
1 162 LEU n 
1 163 SER n 
1 164 GLU n 
1 165 ASP n 
1 166 HIS n 
1 167 ALA n 
1 168 TRP n 
1 169 VAL n 
1 170 VAL n 
1 171 PHE n 
1 172 GLY n 
1 173 PRO n 
1 174 ASN n 
1 175 GLY n 
1 176 GLU n 
1 177 GLN n 
1 178 THR n 
1 179 ALA n 
1 180 GLU n 
1 181 VAL n 
1 182 THR n 
1 183 TRP n 
1 184 HIS n 
1 185 GLY n 
1 186 LYS n 
1 187 GLY n 
1 188 ASN n 
1 189 GLU n 
1 190 ASP n 
1 191 ARG n 
1 192 ARG n 
1 193 GLY n 
1 194 GLN n 
1 195 THR n 
1 196 VAL n 
1 197 ASN n 
1 198 ALA n 
1 199 GLY n 
1 200 VAL n 
1 201 ALA n 
1 202 GLU n 
1 203 ARG n 
1 204 SER n 
1 205 TRP n 
1 206 LEU n 
1 207 TYR n 
1 208 LEU n 
1 209 LYS n 
1 210 GLY n 
1 211 SER n 
1 212 TYR n 
1 213 MET n 
1 214 ARG n 
1 215 CYS n 
1 216 ASP n 
1 217 ARG n 
1 218 LYS n 
1 219 MET n 
1 220 GLU n 
1 221 VAL n 
1 222 ALA n 
1 223 PHE n 
1 224 MET n 
1 225 VAL n 
1 226 CYS n 
1 227 ALA n 
1 228 ILE n 
1 229 ASN n 
1 230 PRO n 
1 231 SER n 
1 232 ILE n 
1 233 ASP n 
1 234 LEU n 
1 235 HIS n 
1 236 THR n 
1 237 ASP n 
1 238 SER n 
1 239 LEU n 
1 240 GLU n 
1 241 LEU n 
1 242 LEU n 
1 243 GLN n 
1 244 LEU n 
1 245 GLN n 
1 246 GLN n 
1 247 LYS n 
1 248 LEU n 
1 249 LEU n 
1 250 TRP n 
1 251 LEU n 
1 252 LEU n 
1 253 TYR n 
1 254 ASP n 
1 255 LEU n 
1 256 GLY n 
1 257 HIS n 
1 258 LEU n 
1 259 GLU n 
1 260 ARG n 
1 261 TYR n 
1 262 PRO n 
1 263 MET n 
1 264 ALA n 
1 265 LEU n 
1 266 GLY n 
1 267 ASN n 
1 268 LEU n 
1 269 ALA n 
1 270 ASP n 
1 271 LEU n 
1 272 GLU n 
1 273 GLU n 
1 274 LEU n 
1 275 GLU n 
1 276 PRO n 
1 277 THR n 
1 278 PRO n 
1 279 GLY n 
1 280 ARG n 
1 281 PRO n 
1 282 ASP n 
1 283 PRO n 
1 284 LEU n 
1 285 THR n 
1 286 LEU n 
1 287 TYR n 
1 288 HIS n 
1 289 LYS n 
1 290 GLY n 
1 291 ILE n 
1 292 ALA n 
1 293 SER n 
1 294 ALA n 
1 295 LYS n 
1 296 THR n 
1 297 TYR n 
1 298 TYR n 
1 299 ARG n 
1 300 ASP n 
1 301 GLU n 
1 302 HIS n 
1 303 ILE n 
1 304 TYR n 
1 305 PRO n 
1 306 TYR n 
1 307 MET n 
1 308 TYR n 
1 309 LEU n 
1 310 ALA n 
1 311 GLY n 
1 312 TYR n 
1 313 HIS n 
1 314 CYS n 
1 315 ARG n 
1 316 ASN n 
1 317 ARG n 
1 318 ASN n 
1 319 VAL n 
1 320 ARG n 
1 321 GLU n 
1 322 ALA n 
1 323 LEU n 
1 324 GLN n 
1 325 ALA n 
1 326 TRP n 
1 327 ALA n 
1 328 ASP n 
1 329 MET n 
1 330 ALA n 
1 331 THR n 
1 332 VAL n 
1 333 ILE n 
1 334 GLN n 
1 335 ASP n 
1 336 TYR n 
1 337 ASN n 
1 338 TYR n 
1 339 CYS n 
1 340 ARG n 
1 341 GLU n 
1 342 ASP n 
1 343 GLU n 
1 344 GLU n 
1 345 ILE n 
1 346 TYR n 
1 347 LYS n 
1 348 GLU n 
1 349 PHE n 
1 350 PHE n 
1 351 GLU n 
1 352 VAL n 
1 353 ALA n 
1 354 ASN n 
1 355 ASP n 
1 356 VAL n 
1 357 ILE n 
1 358 PRO n 
1 359 ASN n 
1 360 LEU n 
1 361 LEU n 
1 362 LYS n 
1 363 GLU n 
1 364 ALA n 
1 365 ALA n 
1 366 SER n 
1 367 LEU n 
1 368 LEU n 
1 369 GLU n 
1 370 ALA n 
1 371 GLY n 
1 372 SER n 
1 373 GLN n 
1 374 GLY n 
1 375 SER n 
1 376 ALA n 
1 377 LEU n 
1 378 GLN n 
1 379 ASP n 
1 380 PRO n 
1 381 GLU n 
1 382 CYS n 
1 383 PHE n 
1 384 ALA n 
1 385 HIS n 
1 386 LEU n 
1 387 LEU n 
1 388 ARG n 
1 389 PHE n 
1 390 TYR n 
1 391 ASP n 
1 392 GLY n 
1 393 ILE n 
1 394 CYS n 
1 395 LYS n 
1 396 TRP n 
1 397 GLU n 
1 398 GLU n 
1 399 GLY n 
1 400 SER n 
1 401 PRO n 
1 402 THR n 
1 403 PRO n 
1 404 VAL n 
1 405 LEU n 
1 406 HIS n 
1 407 VAL n 
1 408 GLY n 
1 409 TRP n 
1 410 ALA n 
1 411 THR n 
1 412 PHE n 
1 413 LEU n 
1 414 VAL n 
1 415 GLN n 
1 416 SER n 
1 417 LEU n 
1 418 GLY n 
1 419 ARG n 
1 420 PHE n 
1 421 GLU n 
1 422 GLY n 
1 423 GLN n 
1 424 VAL n 
1 425 ARG n 
1 426 GLN n 
1 427 LYS n 
1 428 VAL n 
1 429 ARG n 
1 430 ILE n 
1 431 VAL n 
1 432 SER n 
1 433 VAL n 
1 434 PRO n 
1 435 ALA n 
1 436 PRO n 
1 437 THR n 
1 438 ALA n 
1 439 SER n 
1 440 PRO n 
1 441 PRO n 
1 442 PRO n 
1 443 GLU n 
1 444 GLY n 
1 445 PRO n 
1 446 VAL n 
1 447 LEU n 
1 448 THR n 
1 449 PHE n 
1 450 GLN n 
1 451 SER n 
1 452 GLU n 
1 453 LYS n 
1 454 MET n 
1 455 LYS n 
1 456 GLY n 
1 457 MET n 
1 458 LYS n 
1 459 GLU n 
1 460 LEU n 
1 461 LEU n 
1 462 VAL n 
1 463 ALA n 
1 464 THR n 
1 465 LYS n 
1 466 ILE n 
1 467 ASN n 
1 468 SER n 
1 469 SER n 
1 470 ALA n 
1 471 ILE n 
1 472 LYS n 
1 473 LEU n 
1 474 GLN n 
1 475 LEU n 
1 476 THR n 
1 477 ALA n 
1 478 GLN n 
1 479 SER n 
1 480 GLN n 
1 481 VAL n 
1 482 GLN n 
1 483 MET n 
1 484 LYS n 
1 485 LYS n 
1 486 GLN n 
1 487 LYS n 
1 488 VAL n 
1 489 SER n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1   432 human ? 'MEN1, SCG2' ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 'Escherichia coli' 
562 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
1 2 sample 'Biological sequence' 433 489 human ? 'MEN1, SCG2' ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 'Escherichia coli' 
562 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                 ?                 'C3 H7 N O2'          89.093  
ARG 'L-peptide linking' y ARGININE                ?                 'C6 H15 N4 O2 1'      175.209 
ASN 'L-peptide linking' y ASPARAGINE              ?                 'C4 H8 N2 O3'         132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'         ?                 'C4 H7 N O4'          133.103 
CYS 'L-peptide linking' y CYSTEINE                ?                 'C3 H7 N O2 S'        121.158 
DMS non-polymer         . 'DIMETHYL SULFOXIDE'    ?                 'C2 H6 O S'           78.133  
EDO non-polymer         . 1,2-ETHANEDIOL          'ETHYLENE GLYCOL' 'C2 H6 O2'            62.068  
GLN 'L-peptide linking' y GLUTAMINE               ?                 'C5 H10 N2 O3'        146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'         ?                 'C5 H9 N O4'          147.129 
GLY 'peptide linking'   y GLYCINE                 ?                 'C2 H5 N O2'          75.067  
HIS 'L-peptide linking' y HISTIDINE               ?                 'C6 H10 N3 O2 1'      156.162 
HOH non-polymer         . WATER                   ?                 'H2 O'                18.015  
ILE 'L-peptide linking' y ISOLEUCINE              ?                 'C6 H13 N O2'         131.173 
K5O non-polymer         . Ziftomenib              ?                 'C33 H42 F3 N9 O2 S2' 717.871 
LEU 'L-peptide linking' y LEUCINE                 ?                 'C6 H13 N O2'         131.173 
LYS 'L-peptide linking' y LYSINE                  ?                 'C6 H15 N2 O2 1'      147.195 
MET 'L-peptide linking' y METHIONINE              ?                 'C5 H11 N O2 S'       149.211 
PEG non-polymer         . 'DI(HYDROXYETHYL)ETHER' ?                 'C4 H10 O3'           106.120 
PG4 non-polymer         . 'TETRAETHYLENE GLYCOL'  ?                 'C8 H18 O5'           194.226 
PHE 'L-peptide linking' y PHENYLALANINE           ?                 'C9 H11 N O2'         165.189 
PRO 'L-peptide linking' y PROLINE                 ?                 'C5 H9 N O2'          115.130 
SER 'L-peptide linking' y SERINE                  ?                 'C3 H7 N O3'          105.093 
THR 'L-peptide linking' y THREONINE               ?                 'C4 H9 N O3'          119.119 
TRP 'L-peptide linking' y TRYPTOPHAN              ?                 'C11 H12 N2 O2'       204.225 
TYR 'L-peptide linking' y TYROSINE                ?                 'C9 H11 N O3'         181.189 
VAL 'L-peptide linking' y VALINE                  ?                 'C5 H11 N O2'         117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   GLY 1   -4  ?   ?   ?   A . n 
A 1 2   GLY 2   -3  ?   ?   ?   A . n 
A 1 3   SER 3   -2  ?   ?   ?   A . n 
A 1 4   SER 4   -1  ?   ?   ?   A . n 
A 1 5   SER 5   0   ?   ?   ?   A . n 
A 1 6   MET 6   1   ?   ?   ?   A . n 
A 1 7   GLY 7   2   2   GLY GLY A . n 
A 1 8   LEU 8   3   3   LEU LEU A . n 
A 1 9   LYS 9   4   4   LYS LYS A . n 
A 1 10  ALA 10  5   5   ALA ALA A . n 
A 1 11  ALA 11  6   6   ALA ALA A . n 
A 1 12  GLN 12  7   7   GLN GLN A . n 
A 1 13  LYS 13  8   8   LYS LYS A . n 
A 1 14  THR 14  9   9   THR THR A . n 
A 1 15  LEU 15  10  10  LEU LEU A . n 
A 1 16  PHE 16  11  11  PHE PHE A . n 
A 1 17  PRO 17  12  12  PRO PRO A . n 
A 1 18  LEU 18  13  13  LEU LEU A . n 
A 1 19  ARG 19  14  14  ARG ARG A . n 
A 1 20  SER 20  15  15  SER SER A . n 
A 1 21  ILE 21  16  16  ILE ILE A . n 
A 1 22  ASP 22  17  17  ASP ASP A . n 
A 1 23  ASP 23  18  18  ASP ASP A . n 
A 1 24  VAL 24  19  19  VAL VAL A . n 
A 1 25  VAL 25  20  20  VAL VAL A . n 
A 1 26  ARG 26  21  21  ARG ARG A . n 
A 1 27  LEU 27  22  22  LEU LEU A . n 
A 1 28  PHE 28  23  23  PHE PHE A . n 
A 1 29  ALA 29  24  24  ALA ALA A . n 
A 1 30  ALA 30  25  25  ALA ALA A . n 
A 1 31  GLU 31  26  26  GLU GLU A . n 
A 1 32  LEU 32  27  27  LEU LEU A . n 
A 1 33  GLY 33  28  28  GLY GLY A . n 
A 1 34  ARG 34  29  29  ARG ARG A . n 
A 1 35  GLU 35  30  30  GLU GLU A . n 
A 1 36  GLU 36  31  31  GLU GLU A . n 
A 1 37  PRO 37  32  32  PRO PRO A . n 
A 1 38  ASP 38  33  33  ASP ASP A . n 
A 1 39  LEU 39  34  34  LEU LEU A . n 
A 1 40  VAL 40  35  35  VAL VAL A . n 
A 1 41  LEU 41  36  36  LEU LEU A . n 
A 1 42  LEU 42  37  37  LEU LEU A . n 
A 1 43  SER 43  38  38  SER SER A . n 
A 1 44  LEU 44  39  39  LEU LEU A . n 
A 1 45  VAL 45  40  40  VAL VAL A . n 
A 1 46  LEU 46  41  41  LEU LEU A . n 
A 1 47  GLY 47  42  42  GLY GLY A . n 
A 1 48  PHE 48  43  43  PHE PHE A . n 
A 1 49  VAL 49  44  44  VAL VAL A . n 
A 1 50  GLU 50  45  45  GLU GLU A . n 
A 1 51  HIS 51  46  46  HIS HIS A . n 
A 1 52  PHE 52  47  47  PHE PHE A . n 
A 1 53  LEU 53  48  48  LEU LEU A . n 
A 1 54  ALA 54  49  49  ALA ALA A . n 
A 1 55  VAL 55  50  50  VAL VAL A . n 
A 1 56  ASN 56  51  51  ASN ASN A . n 
A 1 57  ARG 57  52  52  ARG ARG A . n 
A 1 58  VAL 58  53  53  VAL VAL A . n 
A 1 59  GLY 59  74  74  GLY GLY A . n 
A 1 60  LEU 60  75  75  LEU LEU A . n 
A 1 61  THR 61  76  76  THR THR A . n 
A 1 62  TYR 62  77  77  TYR TYR A . n 
A 1 63  PHE 63  78  78  PHE PHE A . n 
A 1 64  PRO 64  79  79  PRO PRO A . n 
A 1 65  VAL 65  80  80  VAL VAL A . n 
A 1 66  ALA 66  81  81  ALA ALA A . n 
A 1 67  ASP 67  82  82  ASP ASP A . n 
A 1 68  LEU 68  83  83  LEU LEU A . n 
A 1 69  SER 69  84  84  SER SER A . n 
A 1 70  ILE 70  85  85  ILE ILE A . n 
A 1 71  ILE 71  86  86  ILE ILE A . n 
A 1 72  ALA 72  87  87  ALA ALA A . n 
A 1 73  ALA 73  88  88  ALA ALA A . n 
A 1 74  LEU 74  89  89  LEU LEU A . n 
A 1 75  TYR 75  90  90  TYR TYR A . n 
A 1 76  ALA 76  91  91  ALA ALA A . n 
A 1 77  ARG 77  92  92  ARG ARG A . n 
A 1 78  PHE 78  93  93  PHE PHE A . n 
A 1 79  THR 79  94  94  THR THR A . n 
A 1 80  ALA 80  95  95  ALA ALA A . n 
A 1 81  GLN 81  96  96  GLN GLN A . n 
A 1 82  ILE 82  97  97  ILE ILE A . n 
A 1 83  ARG 83  98  98  ARG ARG A . n 
A 1 84  GLY 84  99  99  GLY GLY A . n 
A 1 85  ALA 85  100 100 ALA ALA A . n 
A 1 86  VAL 86  101 101 VAL VAL A . n 
A 1 87  ASP 87  102 102 ASP ASP A . n 
A 1 88  LEU 88  103 103 LEU LEU A . n 
A 1 89  SER 89  104 104 SER SER A . n 
A 1 90  LEU 90  105 105 LEU LEU A . n 
A 1 91  TYR 91  106 106 TYR TYR A . n 
A 1 92  PRO 92  107 107 PRO PRO A . n 
A 1 93  ARG 93  108 108 ARG ARG A . n 
A 1 94  GLU 94  109 109 GLU GLU A . n 
A 1 95  GLY 95  110 110 GLY GLY A . n 
A 1 96  GLY 96  111 111 GLY GLY A . n 
A 1 97  VAL 97  112 112 VAL VAL A . n 
A 1 98  SER 98  113 113 SER SER A . n 
A 1 99  SER 99  114 114 SER SER A . n 
A 1 100 ARG 100 115 115 ARG ARG A . n 
A 1 101 GLU 101 116 116 GLU GLU A . n 
A 1 102 LEU 102 117 117 LEU LEU A . n 
A 1 103 VAL 103 118 118 VAL VAL A . n 
A 1 104 LYS 104 119 119 LYS LYS A . n 
A 1 105 LYS 105 120 120 LYS LYS A . n 
A 1 106 VAL 106 121 121 VAL VAL A . n 
A 1 107 SER 107 122 122 SER SER A . n 
A 1 108 ASP 108 123 123 ASP ASP A . n 
A 1 109 VAL 109 124 124 VAL VAL A . n 
A 1 110 ILE 110 125 125 ILE ILE A . n 
A 1 111 TRP 111 126 126 TRP TRP A . n 
A 1 112 ASN 112 127 127 ASN ASN A . n 
A 1 113 SER 113 128 128 SER SER A . n 
A 1 114 LEU 114 129 129 LEU LEU A . n 
A 1 115 SER 115 130 130 SER SER A . n 
A 1 116 ARG 116 131 131 ARG ARG A . n 
A 1 117 SER 117 132 132 SER SER A . n 
A 1 118 TYR 118 133 133 TYR TYR A . n 
A 1 119 PHE 119 134 134 PHE PHE A . n 
A 1 120 LYS 120 135 135 LYS LYS A . n 
A 1 121 ASP 121 136 136 ASP ASP A . n 
A 1 122 ARG 122 137 137 ARG ARG A . n 
A 1 123 ALA 123 138 138 ALA ALA A . n 
A 1 124 HIS 124 139 139 HIS HIS A . n 
A 1 125 ILE 125 140 140 ILE ILE A . n 
A 1 126 GLN 126 141 141 GLN GLN A . n 
A 1 127 SER 127 142 142 SER SER A . n 
A 1 128 LEU 128 143 143 LEU LEU A . n 
A 1 129 PHE 129 144 144 PHE PHE A . n 
A 1 130 SER 130 145 145 SER SER A . n 
A 1 131 PHE 131 146 146 PHE PHE A . n 
A 1 132 ILE 132 147 147 ILE ILE A . n 
A 1 133 THR 133 148 148 THR THR A . n 
A 1 134 GLY 134 149 149 GLY GLY A . n 
A 1 135 THR 135 150 150 THR THR A . n 
A 1 136 LYS 136 151 151 LYS LYS A . n 
A 1 137 LEU 137 152 152 LEU LEU A . n 
A 1 138 ASP 138 153 153 ASP ASP A . n 
A 1 139 SER 139 154 154 SER SER A . n 
A 1 140 SER 140 155 155 SER SER A . n 
A 1 141 GLY 141 156 156 GLY GLY A . n 
A 1 142 VAL 142 157 157 VAL VAL A . n 
A 1 143 ALA 143 158 158 ALA ALA A . n 
A 1 144 PHE 144 159 159 PHE PHE A . n 
A 1 145 ALA 145 160 160 ALA ALA A . n 
A 1 146 VAL 146 161 161 VAL VAL A . n 
A 1 147 VAL 147 162 162 VAL VAL A . n 
A 1 148 GLY 148 163 163 GLY GLY A . n 
A 1 149 ALA 149 164 164 ALA ALA A . n 
A 1 150 CYS 150 165 165 CYS CYS A . n 
A 1 151 GLN 151 166 166 GLN GLN A . n 
A 1 152 ALA 152 167 167 ALA ALA A . n 
A 1 153 LEU 153 168 168 LEU LEU A . n 
A 1 154 GLY 154 169 169 GLY GLY A . n 
A 1 155 LEU 155 170 170 LEU LEU A . n 
A 1 156 ARG 156 171 171 ARG ARG A . n 
A 1 157 ASP 157 172 172 ASP ASP A . n 
A 1 158 VAL 158 173 173 VAL VAL A . n 
A 1 159 HIS 159 174 174 HIS HIS A . n 
A 1 160 LEU 160 175 175 LEU LEU A . n 
A 1 161 ALA 161 176 176 ALA ALA A . n 
A 1 162 LEU 162 177 177 LEU LEU A . n 
A 1 163 SER 163 178 178 SER SER A . n 
A 1 164 GLU 164 179 179 GLU GLU A . n 
A 1 165 ASP 165 180 180 ASP ASP A . n 
A 1 166 HIS 166 181 181 HIS HIS A . n 
A 1 167 ALA 167 182 182 ALA ALA A . n 
A 1 168 TRP 168 183 183 TRP TRP A . n 
A 1 169 VAL 169 184 184 VAL VAL A . n 
A 1 170 VAL 170 185 185 VAL VAL A . n 
A 1 171 PHE 171 186 186 PHE PHE A . n 
A 1 172 GLY 172 187 187 GLY GLY A . n 
A 1 173 PRO 173 188 188 PRO PRO A . n 
A 1 174 ASN 174 189 189 ASN ASN A . n 
A 1 175 GLY 175 190 190 GLY GLY A . n 
A 1 176 GLU 176 191 191 GLU GLU A . n 
A 1 177 GLN 177 192 192 GLN GLN A . n 
A 1 178 THR 178 193 193 THR THR A . n 
A 1 179 ALA 179 194 194 ALA ALA A . n 
A 1 180 GLU 180 195 195 GLU GLU A . n 
A 1 181 VAL 181 196 196 VAL VAL A . n 
A 1 182 THR 182 197 197 THR THR A . n 
A 1 183 TRP 183 198 198 TRP TRP A . n 
A 1 184 HIS 184 199 199 HIS HIS A . n 
A 1 185 GLY 185 200 200 GLY GLY A . n 
A 1 186 LYS 186 201 201 LYS LYS A . n 
A 1 187 GLY 187 202 202 GLY GLY A . n 
A 1 188 ASN 188 203 203 ASN ASN A . n 
A 1 189 GLU 189 204 204 GLU GLU A . n 
A 1 190 ASP 190 205 205 ASP ASP A . n 
A 1 191 ARG 191 206 206 ARG ARG A . n 
A 1 192 ARG 192 207 207 ARG ARG A . n 
A 1 193 GLY 193 208 208 GLY GLY A . n 
A 1 194 GLN 194 209 209 GLN GLN A . n 
A 1 195 THR 195 210 210 THR THR A . n 
A 1 196 VAL 196 211 211 VAL VAL A . n 
A 1 197 ASN 197 212 212 ASN ASN A . n 
A 1 198 ALA 198 213 213 ALA ALA A . n 
A 1 199 GLY 199 214 214 GLY GLY A . n 
A 1 200 VAL 200 215 215 VAL VAL A . n 
A 1 201 ALA 201 216 216 ALA ALA A . n 
A 1 202 GLU 202 217 217 GLU GLU A . n 
A 1 203 ARG 203 218 218 ARG ARG A . n 
A 1 204 SER 204 219 219 SER SER A . n 
A 1 205 TRP 205 220 220 TRP TRP A . n 
A 1 206 LEU 206 221 221 LEU LEU A . n 
A 1 207 TYR 207 222 222 TYR TYR A . n 
A 1 208 LEU 208 223 223 LEU LEU A . n 
A 1 209 LYS 209 224 224 LYS LYS A . n 
A 1 210 GLY 210 225 225 GLY GLY A . n 
A 1 211 SER 211 226 226 SER SER A . n 
A 1 212 TYR 212 227 227 TYR TYR A . n 
A 1 213 MET 213 228 228 MET MET A . n 
A 1 214 ARG 214 229 229 ARG ARG A . n 
A 1 215 CYS 215 230 230 CYS CYS A . n 
A 1 216 ASP 216 231 231 ASP ASP A . n 
A 1 217 ARG 217 232 232 ARG ARG A . n 
A 1 218 LYS 218 233 233 LYS LYS A . n 
A 1 219 MET 219 234 234 MET MET A . n 
A 1 220 GLU 220 235 235 GLU GLU A . n 
A 1 221 VAL 221 236 236 VAL VAL A . n 
A 1 222 ALA 222 237 237 ALA ALA A . n 
A 1 223 PHE 223 238 238 PHE PHE A . n 
A 1 224 MET 224 239 239 MET MET A . n 
A 1 225 VAL 225 240 240 VAL VAL A . n 
A 1 226 CYS 226 241 241 CYS CYS A . n 
A 1 227 ALA 227 242 242 ALA ALA A . n 
A 1 228 ILE 228 243 243 ILE ILE A . n 
A 1 229 ASN 229 244 244 ASN ASN A . n 
A 1 230 PRO 230 245 245 PRO PRO A . n 
A 1 231 SER 231 246 246 SER SER A . n 
A 1 232 ILE 232 247 247 ILE ILE A . n 
A 1 233 ASP 233 248 248 ASP ASP A . n 
A 1 234 LEU 234 249 249 LEU LEU A . n 
A 1 235 HIS 235 250 250 HIS HIS A . n 
A 1 236 THR 236 251 251 THR THR A . n 
A 1 237 ASP 237 252 252 ASP ASP A . n 
A 1 238 SER 238 253 253 SER SER A . n 
A 1 239 LEU 239 254 254 LEU LEU A . n 
A 1 240 GLU 240 255 255 GLU GLU A . n 
A 1 241 LEU 241 256 256 LEU LEU A . n 
A 1 242 LEU 242 257 257 LEU LEU A . n 
A 1 243 GLN 243 258 258 GLN GLN A . n 
A 1 244 LEU 244 259 259 LEU LEU A . n 
A 1 245 GLN 245 260 260 GLN GLN A . n 
A 1 246 GLN 246 261 261 GLN GLN A . n 
A 1 247 LYS 247 262 262 LYS LYS A . n 
A 1 248 LEU 248 263 263 LEU LEU A . n 
A 1 249 LEU 249 264 264 LEU LEU A . n 
A 1 250 TRP 250 265 265 TRP TRP A . n 
A 1 251 LEU 251 266 266 LEU LEU A . n 
A 1 252 LEU 252 267 267 LEU LEU A . n 
A 1 253 TYR 253 268 268 TYR TYR A . n 
A 1 254 ASP 254 269 269 ASP ASP A . n 
A 1 255 LEU 255 270 270 LEU LEU A . n 
A 1 256 GLY 256 271 271 GLY GLY A . n 
A 1 257 HIS 257 272 272 HIS HIS A . n 
A 1 258 LEU 258 273 273 LEU LEU A . n 
A 1 259 GLU 259 274 274 GLU GLU A . n 
A 1 260 ARG 260 275 275 ARG ARG A . n 
A 1 261 TYR 261 276 276 TYR TYR A . n 
A 1 262 PRO 262 277 277 PRO PRO A . n 
A 1 263 MET 263 278 278 MET MET A . n 
A 1 264 ALA 264 279 279 ALA ALA A . n 
A 1 265 LEU 265 280 280 LEU LEU A . n 
A 1 266 GLY 266 281 281 GLY GLY A . n 
A 1 267 ASN 267 282 282 ASN ASN A . n 
A 1 268 LEU 268 283 283 LEU LEU A . n 
A 1 269 ALA 269 284 284 ALA ALA A . n 
A 1 270 ASP 270 285 285 ASP ASP A . n 
A 1 271 LEU 271 286 286 LEU LEU A . n 
A 1 272 GLU 272 287 287 GLU GLU A . n 
A 1 273 GLU 273 288 288 GLU GLU A . n 
A 1 274 LEU 274 289 289 LEU LEU A . n 
A 1 275 GLU 275 290 290 GLU GLU A . n 
A 1 276 PRO 276 291 291 PRO PRO A . n 
A 1 277 THR 277 292 292 THR THR A . n 
A 1 278 PRO 278 293 293 PRO PRO A . n 
A 1 279 GLY 279 294 294 GLY GLY A . n 
A 1 280 ARG 280 295 295 ARG ARG A . n 
A 1 281 PRO 281 296 296 PRO PRO A . n 
A 1 282 ASP 282 297 297 ASP ASP A . n 
A 1 283 PRO 283 298 298 PRO PRO A . n 
A 1 284 LEU 284 299 299 LEU LEU A . n 
A 1 285 THR 285 300 300 THR THR A . n 
A 1 286 LEU 286 301 301 LEU LEU A . n 
A 1 287 TYR 287 302 302 TYR TYR A . n 
A 1 288 HIS 288 303 303 HIS HIS A . n 
A 1 289 LYS 289 304 304 LYS LYS A . n 
A 1 290 GLY 290 305 305 GLY GLY A . n 
A 1 291 ILE 291 306 306 ILE ILE A . n 
A 1 292 ALA 292 307 307 ALA ALA A . n 
A 1 293 SER 293 308 308 SER SER A . n 
A 1 294 ALA 294 309 309 ALA ALA A . n 
A 1 295 LYS 295 310 310 LYS LYS A . n 
A 1 296 THR 296 311 311 THR THR A . n 
A 1 297 TYR 297 312 312 TYR TYR A . n 
A 1 298 TYR 298 313 313 TYR TYR A . n 
A 1 299 ARG 299 314 314 ARG ARG A . n 
A 1 300 ASP 300 315 315 ASP ASP A . n 
A 1 301 GLU 301 316 316 GLU GLU A . n 
A 1 302 HIS 302 317 317 HIS HIS A . n 
A 1 303 ILE 303 318 318 ILE ILE A . n 
A 1 304 TYR 304 319 319 TYR TYR A . n 
A 1 305 PRO 305 320 320 PRO PRO A . n 
A 1 306 TYR 306 321 321 TYR TYR A . n 
A 1 307 MET 307 322 322 MET MET A . n 
A 1 308 TYR 308 323 323 TYR TYR A . n 
A 1 309 LEU 309 324 324 LEU LEU A . n 
A 1 310 ALA 310 325 325 ALA ALA A . n 
A 1 311 GLY 311 326 326 GLY GLY A . n 
A 1 312 TYR 312 327 327 TYR TYR A . n 
A 1 313 HIS 313 328 328 HIS HIS A . n 
A 1 314 CYS 314 329 329 CYS CYS A . n 
A 1 315 ARG 315 330 330 ARG ARG A . n 
A 1 316 ASN 316 331 331 ASN ASN A . n 
A 1 317 ARG 317 332 332 ARG ARG A . n 
A 1 318 ASN 318 333 333 ASN ASN A . n 
A 1 319 VAL 319 334 334 VAL VAL A . n 
A 1 320 ARG 320 335 335 ARG ARG A . n 
A 1 321 GLU 321 336 336 GLU GLU A . n 
A 1 322 ALA 322 337 337 ALA ALA A . n 
A 1 323 LEU 323 338 338 LEU LEU A . n 
A 1 324 GLN 324 339 339 GLN GLN A . n 
A 1 325 ALA 325 340 340 ALA ALA A . n 
A 1 326 TRP 326 341 341 TRP TRP A . n 
A 1 327 ALA 327 342 342 ALA ALA A . n 
A 1 328 ASP 328 343 343 ASP ASP A . n 
A 1 329 MET 329 344 344 MET MET A . n 
A 1 330 ALA 330 345 345 ALA ALA A . n 
A 1 331 THR 331 346 346 THR THR A . n 
A 1 332 VAL 332 347 347 VAL VAL A . n 
A 1 333 ILE 333 348 348 ILE ILE A . n 
A 1 334 GLN 334 349 349 GLN GLN A . n 
A 1 335 ASP 335 350 350 ASP ASP A . n 
A 1 336 TYR 336 351 351 TYR TYR A . n 
A 1 337 ASN 337 352 352 ASN ASN A . n 
A 1 338 TYR 338 353 353 TYR TYR A . n 
A 1 339 CYS 339 354 354 CYS CYS A . n 
A 1 340 ARG 340 355 355 ARG ARG A . n 
A 1 341 GLU 341 356 356 GLU GLU A . n 
A 1 342 ASP 342 357 357 ASP ASP A . n 
A 1 343 GLU 343 358 358 GLU GLU A . n 
A 1 344 GLU 344 359 359 GLU GLU A . n 
A 1 345 ILE 345 360 360 ILE ILE A . n 
A 1 346 TYR 346 361 361 TYR TYR A . n 
A 1 347 LYS 347 362 362 LYS LYS A . n 
A 1 348 GLU 348 363 363 GLU GLU A . n 
A 1 349 PHE 349 364 364 PHE PHE A . n 
A 1 350 PHE 350 365 365 PHE PHE A . n 
A 1 351 GLU 351 366 366 GLU GLU A . n 
A 1 352 VAL 352 367 367 VAL VAL A . n 
A 1 353 ALA 353 368 368 ALA ALA A . n 
A 1 354 ASN 354 369 369 ASN ASN A . n 
A 1 355 ASP 355 370 370 ASP ASP A . n 
A 1 356 VAL 356 371 371 VAL VAL A . n 
A 1 357 ILE 357 372 372 ILE ILE A . n 
A 1 358 PRO 358 373 373 PRO PRO A . n 
A 1 359 ASN 359 374 374 ASN ASN A . n 
A 1 360 LEU 360 375 375 LEU LEU A . n 
A 1 361 LEU 361 376 376 LEU LEU A . n 
A 1 362 LYS 362 377 377 LYS LYS A . n 
A 1 363 GLU 363 378 378 GLU GLU A . n 
A 1 364 ALA 364 379 379 ALA ALA A . n 
A 1 365 ALA 365 380 380 ALA ALA A . n 
A 1 366 SER 366 381 381 SER SER A . n 
A 1 367 LEU 367 382 382 LEU LEU A . n 
A 1 368 LEU 368 383 383 LEU LEU A . n 
A 1 369 GLU 369 384 384 GLU GLU A . n 
A 1 370 ALA 370 385 385 ALA ALA A . n 
A 1 371 GLY 371 386 386 GLY GLY A . n 
A 1 372 SER 372 399 399 SER SER A . n 
A 1 373 GLN 373 400 400 GLN GLN A . n 
A 1 374 GLY 374 401 401 GLY GLY A . n 
A 1 375 SER 375 402 402 SER SER A . n 
A 1 376 ALA 376 403 403 ALA ALA A . n 
A 1 377 LEU 377 404 404 LEU LEU A . n 
A 1 378 GLN 378 405 405 GLN GLN A . n 
A 1 379 ASP 379 406 406 ASP ASP A . n 
A 1 380 PRO 380 407 407 PRO PRO A . n 
A 1 381 GLU 381 408 408 GLU GLU A . n 
A 1 382 CYS 382 409 409 CYS CYS A . n 
A 1 383 PHE 383 410 410 PHE PHE A . n 
A 1 384 ALA 384 411 411 ALA ALA A . n 
A 1 385 HIS 385 412 412 HIS HIS A . n 
A 1 386 LEU 386 413 413 LEU LEU A . n 
A 1 387 LEU 387 414 414 LEU LEU A . n 
A 1 388 ARG 388 415 415 ARG ARG A . n 
A 1 389 PHE 389 416 416 PHE PHE A . n 
A 1 390 TYR 390 417 417 TYR TYR A . n 
A 1 391 ASP 391 418 418 ASP ASP A . n 
A 1 392 GLY 392 419 419 GLY GLY A . n 
A 1 393 ILE 393 420 420 ILE ILE A . n 
A 1 394 CYS 394 421 421 CYS CYS A . n 
A 1 395 LYS 395 422 422 LYS LYS A . n 
A 1 396 TRP 396 423 423 TRP TRP A . n 
A 1 397 GLU 397 424 424 GLU GLU A . n 
A 1 398 GLU 398 425 425 GLU GLU A . n 
A 1 399 GLY 399 426 426 GLY GLY A . n 
A 1 400 SER 400 427 427 SER SER A . n 
A 1 401 PRO 401 428 428 PRO PRO A . n 
A 1 402 THR 402 429 429 THR THR A . n 
A 1 403 PRO 403 430 430 PRO PRO A . n 
A 1 404 VAL 404 431 431 VAL VAL A . n 
A 1 405 LEU 405 432 432 LEU LEU A . n 
A 1 406 HIS 406 433 433 HIS HIS A . n 
A 1 407 VAL 407 434 434 VAL VAL A . n 
A 1 408 GLY 408 435 435 GLY GLY A . n 
A 1 409 TRP 409 436 436 TRP TRP A . n 
A 1 410 ALA 410 437 437 ALA ALA A . n 
A 1 411 THR 411 438 438 THR THR A . n 
A 1 412 PHE 412 439 439 PHE PHE A . n 
A 1 413 LEU 413 440 440 LEU LEU A . n 
A 1 414 VAL 414 441 441 VAL VAL A . n 
A 1 415 GLN 415 442 442 GLN GLN A . n 
A 1 416 SER 416 443 443 SER SER A . n 
A 1 417 LEU 417 444 444 LEU LEU A . n 
A 1 418 GLY 418 445 445 GLY GLY A . n 
A 1 419 ARG 419 446 446 ARG ARG A . n 
A 1 420 PHE 420 447 447 PHE PHE A . n 
A 1 421 GLU 421 448 448 GLU GLU A . n 
A 1 422 GLY 422 449 449 GLY GLY A . n 
A 1 423 GLN 423 450 450 GLN GLN A . n 
A 1 424 VAL 424 451 451 VAL VAL A . n 
A 1 425 ARG 425 452 452 ARG ARG A . n 
A 1 426 GLN 426 453 453 GLN GLN A . n 
A 1 427 LYS 427 454 454 LYS LYS A . n 
A 1 428 VAL 428 455 455 VAL VAL A . n 
A 1 429 ARG 429 456 456 ARG ARG A . n 
A 1 430 ILE 430 457 457 ILE ILE A . n 
A 1 431 VAL 431 458 458 VAL VAL A . n 
A 1 432 SER 432 459 459 SER SER A . n 
A 1 433 VAL 433 460 460 VAL VAL A . n 
A 1 434 PRO 434 538 ?   ?   ?   A . n 
A 1 435 ALA 435 539 ?   ?   ?   A . n 
A 1 436 PRO 436 540 ?   ?   ?   A . n 
A 1 437 THR 437 541 ?   ?   ?   A . n 
A 1 438 ALA 438 542 ?   ?   ?   A . n 
A 1 439 SER 439 543 ?   ?   ?   A . n 
A 1 440 PRO 440 544 ?   ?   ?   A . n 
A 1 441 PRO 441 545 ?   ?   ?   A . n 
A 1 442 PRO 442 546 ?   ?   ?   A . n 
A 1 443 GLU 443 547 ?   ?   ?   A . n 
A 1 444 GLY 444 548 ?   ?   ?   A . n 
A 1 445 PRO 445 549 549 PRO PRO A . n 
A 1 446 VAL 446 550 550 VAL VAL A . n 
A 1 447 LEU 447 551 551 LEU LEU A . n 
A 1 448 THR 448 552 552 THR THR A . n 
A 1 449 PHE 449 553 553 PHE PHE A . n 
A 1 450 GLN 450 554 554 GLN GLN A . n 
A 1 451 SER 451 555 555 SER SER A . n 
A 1 452 GLU 452 556 556 GLU GLU A . n 
A 1 453 LYS 453 557 557 LYS LYS A . n 
A 1 454 MET 454 558 558 MET MET A . n 
A 1 455 LYS 455 559 559 LYS LYS A . n 
A 1 456 GLY 456 560 560 GLY GLY A . n 
A 1 457 MET 457 561 561 MET MET A . n 
A 1 458 LYS 458 562 562 LYS LYS A . n 
A 1 459 GLU 459 563 563 GLU GLU A . n 
A 1 460 LEU 460 564 564 LEU LEU A . n 
A 1 461 LEU 461 565 565 LEU LEU A . n 
A 1 462 VAL 462 566 566 VAL VAL A . n 
A 1 463 ALA 463 567 567 ALA ALA A . n 
A 1 464 THR 464 568 568 THR THR A . n 
A 1 465 LYS 465 569 569 LYS LYS A . n 
A 1 466 ILE 466 570 570 ILE ILE A . n 
A 1 467 ASN 467 571 571 ASN ASN A . n 
A 1 468 SER 468 572 572 SER SER A . n 
A 1 469 SER 469 573 573 SER SER A . n 
A 1 470 ALA 470 574 574 ALA ALA A . n 
A 1 471 ILE 471 575 575 ILE ILE A . n 
A 1 472 LYS 472 576 576 LYS LYS A . n 
A 1 473 LEU 473 577 577 LEU LEU A . n 
A 1 474 GLN 474 578 578 GLN GLN A . n 
A 1 475 LEU 475 579 579 LEU LEU A . n 
A 1 476 THR 476 580 580 THR THR A . n 
A 1 477 ALA 477 581 581 ALA ALA A . n 
A 1 478 GLN 478 582 582 GLN GLN A . n 
A 1 479 SER 479 583 583 SER SER A . n 
A 1 480 GLN 480 584 584 GLN GLN A . n 
A 1 481 VAL 481 585 585 VAL VAL A . n 
A 1 482 GLN 482 586 586 GLN GLN A . n 
A 1 483 MET 483 587 587 MET MET A . n 
A 1 484 LYS 484 588 588 LYS LYS A . n 
A 1 485 LYS 485 589 ?   ?   ?   A . n 
A 1 486 GLN 486 590 ?   ?   ?   A . n 
A 1 487 LYS 487 591 ?   ?   ?   A . n 
A 1 488 VAL 488 592 ?   ?   ?   A . n 
A 1 489 SER 489 593 ?   ?   ?   A . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        K5O 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   K5O 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
B 2 K5O 1   601  601 K5O LIG A . 
C 3 PEG 1   602  1   PEG PEG A . 
D 4 PG4 1   603  2   PG4 PG4 A . 
E 3 PEG 1   604  3   PEG PEG A . 
F 5 EDO 1   605  4   EDO EDO A . 
G 6 DMS 1   606  5   DMS DMS A . 
H 6 DMS 1   607  6   DMS DMS A . 
I 7 HOH 1   701  526 HOH HOH A . 
I 7 HOH 2   702  432 HOH HOH A . 
I 7 HOH 3   703  541 HOH HOH A . 
I 7 HOH 4   704  378 HOH HOH A . 
I 7 HOH 5   705  227 HOH HOH A . 
I 7 HOH 6   706  63  HOH HOH A . 
I 7 HOH 7   707  545 HOH HOH A . 
I 7 HOH 8   708  430 HOH HOH A . 
I 7 HOH 9   709  567 HOH HOH A . 
I 7 HOH 10  710  497 HOH HOH A . 
I 7 HOH 11  711  623 HOH HOH A . 
I 7 HOH 12  712  200 HOH HOH A . 
I 7 HOH 13  713  573 HOH HOH A . 
I 7 HOH 14  714  70  HOH HOH A . 
I 7 HOH 15  715  507 HOH HOH A . 
I 7 HOH 16  716  203 HOH HOH A . 
I 7 HOH 17  717  537 HOH HOH A . 
I 7 HOH 18  718  339 HOH HOH A . 
I 7 HOH 19  719  282 HOH HOH A . 
I 7 HOH 20  720  55  HOH HOH A . 
I 7 HOH 21  721  408 HOH HOH A . 
I 7 HOH 22  722  577 HOH HOH A . 
I 7 HOH 23  723  606 HOH HOH A . 
I 7 HOH 24  724  156 HOH HOH A . 
I 7 HOH 25  725  254 HOH HOH A . 
I 7 HOH 26  726  354 HOH HOH A . 
I 7 HOH 27  727  230 HOH HOH A . 
I 7 HOH 28  728  359 HOH HOH A . 
I 7 HOH 29  729  397 HOH HOH A . 
I 7 HOH 30  730  392 HOH HOH A . 
I 7 HOH 31  731  286 HOH HOH A . 
I 7 HOH 32  732  601 HOH HOH A . 
I 7 HOH 33  733  627 HOH HOH A . 
I 7 HOH 34  734  371 HOH HOH A . 
I 7 HOH 35  735  610 HOH HOH A . 
I 7 HOH 36  736  320 HOH HOH A . 
I 7 HOH 37  737  172 HOH HOH A . 
I 7 HOH 38  738  208 HOH HOH A . 
I 7 HOH 39  739  588 HOH HOH A . 
I 7 HOH 40  740  515 HOH HOH A . 
I 7 HOH 41  741  293 HOH HOH A . 
I 7 HOH 42  742  162 HOH HOH A . 
I 7 HOH 43  743  521 HOH HOH A . 
I 7 HOH 44  744  317 HOH HOH A . 
I 7 HOH 45  745  388 HOH HOH A . 
I 7 HOH 46  746  383 HOH HOH A . 
I 7 HOH 47  747  333 HOH HOH A . 
I 7 HOH 48  748  336 HOH HOH A . 
I 7 HOH 49  749  508 HOH HOH A . 
I 7 HOH 50  750  370 HOH HOH A . 
I 7 HOH 51  751  10  HOH HOH A . 
I 7 HOH 52  752  356 HOH HOH A . 
I 7 HOH 53  753  470 HOH HOH A . 
I 7 HOH 54  754  1   HOH HOH A . 
I 7 HOH 55  755  372 HOH HOH A . 
I 7 HOH 56  756  309 HOH HOH A . 
I 7 HOH 57  757  322 HOH HOH A . 
I 7 HOH 58  758  197 HOH HOH A . 
I 7 HOH 59  759  578 HOH HOH A . 
I 7 HOH 60  760  425 HOH HOH A . 
I 7 HOH 61  761  344 HOH HOH A . 
I 7 HOH 62  762  115 HOH HOH A . 
I 7 HOH 63  763  296 HOH HOH A . 
I 7 HOH 64  764  493 HOH HOH A . 
I 7 HOH 65  765  38  HOH HOH A . 
I 7 HOH 66  766  599 HOH HOH A . 
I 7 HOH 67  767  402 HOH HOH A . 
I 7 HOH 68  768  374 HOH HOH A . 
I 7 HOH 69  769  245 HOH HOH A . 
I 7 HOH 70  770  82  HOH HOH A . 
I 7 HOH 71  771  505 HOH HOH A . 
I 7 HOH 72  772  65  HOH HOH A . 
I 7 HOH 73  773  41  HOH HOH A . 
I 7 HOH 74  774  367 HOH HOH A . 
I 7 HOH 75  775  28  HOH HOH A . 
I 7 HOH 76  776  240 HOH HOH A . 
I 7 HOH 77  777  341 HOH HOH A . 
I 7 HOH 78  778  559 HOH HOH A . 
I 7 HOH 79  779  76  HOH HOH A . 
I 7 HOH 80  780  160 HOH HOH A . 
I 7 HOH 81  781  260 HOH HOH A . 
I 7 HOH 82  782  520 HOH HOH A . 
I 7 HOH 83  783  71  HOH HOH A . 
I 7 HOH 84  784  116 HOH HOH A . 
I 7 HOH 85  785  364 HOH HOH A . 
I 7 HOH 86  786  135 HOH HOH A . 
I 7 HOH 87  787  170 HOH HOH A . 
I 7 HOH 88  788  29  HOH HOH A . 
I 7 HOH 89  789  191 HOH HOH A . 
I 7 HOH 90  790  17  HOH HOH A . 
I 7 HOH 91  791  95  HOH HOH A . 
I 7 HOH 92  792  512 HOH HOH A . 
I 7 HOH 93  793  150 HOH HOH A . 
I 7 HOH 94  794  181 HOH HOH A . 
I 7 HOH 95  795  215 HOH HOH A . 
I 7 HOH 96  796  535 HOH HOH A . 
I 7 HOH 97  797  113 HOH HOH A . 
I 7 HOH 98  798  136 HOH HOH A . 
I 7 HOH 99  799  36  HOH HOH A . 
I 7 HOH 100 800  362 HOH HOH A . 
I 7 HOH 101 801  244 HOH HOH A . 
I 7 HOH 102 802  597 HOH HOH A . 
I 7 HOH 103 803  40  HOH HOH A . 
I 7 HOH 104 804  177 HOH HOH A . 
I 7 HOH 105 805  235 HOH HOH A . 
I 7 HOH 106 806  463 HOH HOH A . 
I 7 HOH 107 807  114 HOH HOH A . 
I 7 HOH 108 808  450 HOH HOH A . 
I 7 HOH 109 809  355 HOH HOH A . 
I 7 HOH 110 810  195 HOH HOH A . 
I 7 HOH 111 811  179 HOH HOH A . 
I 7 HOH 112 812  105 HOH HOH A . 
I 7 HOH 113 813  26  HOH HOH A . 
I 7 HOH 114 814  9   HOH HOH A . 
I 7 HOH 115 815  403 HOH HOH A . 
I 7 HOH 116 816  187 HOH HOH A . 
I 7 HOH 117 817  69  HOH HOH A . 
I 7 HOH 118 818  562 HOH HOH A . 
I 7 HOH 119 819  100 HOH HOH A . 
I 7 HOH 120 820  77  HOH HOH A . 
I 7 HOH 121 821  422 HOH HOH A . 
I 7 HOH 122 822  23  HOH HOH A . 
I 7 HOH 123 823  142 HOH HOH A . 
I 7 HOH 124 824  13  HOH HOH A . 
I 7 HOH 125 825  607 HOH HOH A . 
I 7 HOH 126 826  458 HOH HOH A . 
I 7 HOH 127 827  538 HOH HOH A . 
I 7 HOH 128 828  405 HOH HOH A . 
I 7 HOH 129 829  32  HOH HOH A . 
I 7 HOH 130 830  229 HOH HOH A . 
I 7 HOH 131 831  85  HOH HOH A . 
I 7 HOH 132 832  102 HOH HOH A . 
I 7 HOH 133 833  287 HOH HOH A . 
I 7 HOH 134 834  89  HOH HOH A . 
I 7 HOH 135 835  56  HOH HOH A . 
I 7 HOH 136 836  139 HOH HOH A . 
I 7 HOH 137 837  494 HOH HOH A . 
I 7 HOH 138 838  24  HOH HOH A . 
I 7 HOH 139 839  587 HOH HOH A . 
I 7 HOH 140 840  4   HOH HOH A . 
I 7 HOH 141 841  210 HOH HOH A . 
I 7 HOH 142 842  161 HOH HOH A . 
I 7 HOH 143 843  37  HOH HOH A . 
I 7 HOH 144 844  15  HOH HOH A . 
I 7 HOH 145 845  182 HOH HOH A . 
I 7 HOH 146 846  625 HOH HOH A . 
I 7 HOH 147 847  184 HOH HOH A . 
I 7 HOH 148 848  243 HOH HOH A . 
I 7 HOH 149 849  579 HOH HOH A . 
I 7 HOH 150 850  467 HOH HOH A . 
I 7 HOH 151 851  319 HOH HOH A . 
I 7 HOH 152 852  274 HOH HOH A . 
I 7 HOH 153 853  192 HOH HOH A . 
I 7 HOH 154 854  409 HOH HOH A . 
I 7 HOH 155 855  266 HOH HOH A . 
I 7 HOH 156 856  312 HOH HOH A . 
I 7 HOH 157 857  246 HOH HOH A . 
I 7 HOH 158 858  193 HOH HOH A . 
I 7 HOH 159 859  301 HOH HOH A . 
I 7 HOH 160 860  152 HOH HOH A . 
I 7 HOH 161 861  205 HOH HOH A . 
I 7 HOH 162 862  481 HOH HOH A . 
I 7 HOH 163 863  544 HOH HOH A . 
I 7 HOH 164 864  626 HOH HOH A . 
I 7 HOH 165 865  107 HOH HOH A . 
I 7 HOH 166 866  16  HOH HOH A . 
I 7 HOH 167 867  123 HOH HOH A . 
I 7 HOH 168 868  149 HOH HOH A . 
I 7 HOH 169 869  42  HOH HOH A . 
I 7 HOH 170 870  21  HOH HOH A . 
I 7 HOH 171 871  252 HOH HOH A . 
I 7 HOH 172 872  35  HOH HOH A . 
I 7 HOH 173 873  47  HOH HOH A . 
I 7 HOH 174 874  67  HOH HOH A . 
I 7 HOH 175 875  7   HOH HOH A . 
I 7 HOH 176 876  441 HOH HOH A . 
I 7 HOH 177 877  31  HOH HOH A . 
I 7 HOH 178 878  379 HOH HOH A . 
I 7 HOH 179 879  498 HOH HOH A . 
I 7 HOH 180 880  164 HOH HOH A . 
I 7 HOH 181 881  68  HOH HOH A . 
I 7 HOH 182 882  43  HOH HOH A . 
I 7 HOH 183 883  132 HOH HOH A . 
I 7 HOH 184 884  262 HOH HOH A . 
I 7 HOH 185 885  241 HOH HOH A . 
I 7 HOH 186 886  83  HOH HOH A . 
I 7 HOH 187 887  12  HOH HOH A . 
I 7 HOH 188 888  263 HOH HOH A . 
I 7 HOH 189 889  111 HOH HOH A . 
I 7 HOH 190 890  290 HOH HOH A . 
I 7 HOH 191 891  158 HOH HOH A . 
I 7 HOH 192 892  94  HOH HOH A . 
I 7 HOH 193 893  349 HOH HOH A . 
I 7 HOH 194 894  315 HOH HOH A . 
I 7 HOH 195 895  73  HOH HOH A . 
I 7 HOH 196 896  598 HOH HOH A . 
I 7 HOH 197 897  8   HOH HOH A . 
I 7 HOH 198 898  81  HOH HOH A . 
I 7 HOH 199 899  104 HOH HOH A . 
I 7 HOH 200 900  129 HOH HOH A . 
I 7 HOH 201 901  52  HOH HOH A . 
I 7 HOH 202 902  14  HOH HOH A . 
I 7 HOH 203 903  209 HOH HOH A . 
I 7 HOH 204 904  117 HOH HOH A . 
I 7 HOH 205 905  223 HOH HOH A . 
I 7 HOH 206 906  492 HOH HOH A . 
I 7 HOH 207 907  110 HOH HOH A . 
I 7 HOH 208 908  166 HOH HOH A . 
I 7 HOH 209 909  127 HOH HOH A . 
I 7 HOH 210 910  78  HOH HOH A . 
I 7 HOH 211 911  536 HOH HOH A . 
I 7 HOH 212 912  219 HOH HOH A . 
I 7 HOH 213 913  57  HOH HOH A . 
I 7 HOH 214 914  58  HOH HOH A . 
I 7 HOH 215 915  482 HOH HOH A . 
I 7 HOH 216 916  118 HOH HOH A . 
I 7 HOH 217 917  190 HOH HOH A . 
I 7 HOH 218 918  211 HOH HOH A . 
I 7 HOH 219 919  64  HOH HOH A . 
I 7 HOH 220 920  34  HOH HOH A . 
I 7 HOH 221 921  53  HOH HOH A . 
I 7 HOH 222 922  108 HOH HOH A . 
I 7 HOH 223 923  19  HOH HOH A . 
I 7 HOH 224 924  59  HOH HOH A . 
I 7 HOH 225 925  304 HOH HOH A . 
I 7 HOH 226 926  445 HOH HOH A . 
I 7 HOH 227 927  466 HOH HOH A . 
I 7 HOH 228 928  96  HOH HOH A . 
I 7 HOH 229 929  39  HOH HOH A . 
I 7 HOH 230 930  168 HOH HOH A . 
I 7 HOH 231 931  289 HOH HOH A . 
I 7 HOH 232 932  258 HOH HOH A . 
I 7 HOH 233 933  25  HOH HOH A . 
I 7 HOH 234 934  185 HOH HOH A . 
I 7 HOH 235 935  130 HOH HOH A . 
I 7 HOH 236 936  122 HOH HOH A . 
I 7 HOH 237 937  279 HOH HOH A . 
I 7 HOH 238 938  277 HOH HOH A . 
I 7 HOH 239 939  183 HOH HOH A . 
I 7 HOH 240 940  329 HOH HOH A . 
I 7 HOH 241 941  300 HOH HOH A . 
I 7 HOH 242 942  146 HOH HOH A . 
I 7 HOH 243 943  271 HOH HOH A . 
I 7 HOH 244 944  106 HOH HOH A . 
I 7 HOH 245 945  112 HOH HOH A . 
I 7 HOH 246 946  267 HOH HOH A . 
I 7 HOH 247 947  318 HOH HOH A . 
I 7 HOH 248 948  393 HOH HOH A . 
I 7 HOH 249 949  220 HOH HOH A . 
I 7 HOH 250 950  2   HOH HOH A . 
I 7 HOH 251 951  151 HOH HOH A . 
I 7 HOH 252 952  571 HOH HOH A . 
I 7 HOH 253 953  373 HOH HOH A . 
I 7 HOH 254 954  148 HOH HOH A . 
I 7 HOH 255 955  297 HOH HOH A . 
I 7 HOH 256 956  92  HOH HOH A . 
I 7 HOH 257 957  381 HOH HOH A . 
I 7 HOH 258 958  138 HOH HOH A . 
I 7 HOH 259 959  99  HOH HOH A . 
I 7 HOH 260 960  87  HOH HOH A . 
I 7 HOH 261 961  404 HOH HOH A . 
I 7 HOH 262 962  18  HOH HOH A . 
I 7 HOH 263 963  207 HOH HOH A . 
I 7 HOH 264 964  86  HOH HOH A . 
I 7 HOH 265 965  483 HOH HOH A . 
I 7 HOH 266 966  495 HOH HOH A . 
I 7 HOH 267 967  91  HOH HOH A . 
I 7 HOH 268 968  186 HOH HOH A . 
I 7 HOH 269 969  44  HOH HOH A . 
I 7 HOH 270 970  414 HOH HOH A . 
I 7 HOH 271 971  147 HOH HOH A . 
I 7 HOH 272 972  48  HOH HOH A . 
I 7 HOH 273 973  171 HOH HOH A . 
I 7 HOH 274 974  93  HOH HOH A . 
I 7 HOH 275 975  61  HOH HOH A . 
I 7 HOH 276 976  159 HOH HOH A . 
I 7 HOH 277 977  60  HOH HOH A . 
I 7 HOH 278 978  137 HOH HOH A . 
I 7 HOH 279 979  5   HOH HOH A . 
I 7 HOH 280 980  334 HOH HOH A . 
I 7 HOH 281 981  224 HOH HOH A . 
I 7 HOH 282 982  528 HOH HOH A . 
I 7 HOH 283 983  165 HOH HOH A . 
I 7 HOH 284 984  437 HOH HOH A . 
I 7 HOH 285 985  140 HOH HOH A . 
I 7 HOH 286 986  446 HOH HOH A . 
I 7 HOH 287 987  194 HOH HOH A . 
I 7 HOH 288 988  352 HOH HOH A . 
I 7 HOH 289 989  454 HOH HOH A . 
I 7 HOH 290 990  51  HOH HOH A . 
I 7 HOH 291 991  302 HOH HOH A . 
I 7 HOH 292 992  54  HOH HOH A . 
I 7 HOH 293 993  206 HOH HOH A . 
I 7 HOH 294 994  22  HOH HOH A . 
I 7 HOH 295 995  382 HOH HOH A . 
I 7 HOH 296 996  234 HOH HOH A . 
I 7 HOH 297 997  121 HOH HOH A . 
I 7 HOH 298 998  213 HOH HOH A . 
I 7 HOH 299 999  75  HOH HOH A . 
I 7 HOH 300 1000 401 HOH HOH A . 
I 7 HOH 301 1001 428 HOH HOH A . 
I 7 HOH 302 1002 120 HOH HOH A . 
I 7 HOH 303 1003 174 HOH HOH A . 
I 7 HOH 304 1004 533 HOH HOH A . 
I 7 HOH 305 1005 33  HOH HOH A . 
I 7 HOH 306 1006 11  HOH HOH A . 
I 7 HOH 307 1007 321 HOH HOH A . 
I 7 HOH 308 1008 188 HOH HOH A . 
I 7 HOH 309 1009 269 HOH HOH A . 
I 7 HOH 310 1010 80  HOH HOH A . 
I 7 HOH 311 1011 144 HOH HOH A . 
I 7 HOH 312 1012 365 HOH HOH A . 
I 7 HOH 313 1013 540 HOH HOH A . 
I 7 HOH 314 1014 46  HOH HOH A . 
I 7 HOH 315 1015 131 HOH HOH A . 
I 7 HOH 316 1016 50  HOH HOH A . 
I 7 HOH 317 1017 173 HOH HOH A . 
I 7 HOH 318 1018 534 HOH HOH A . 
I 7 HOH 319 1019 368 HOH HOH A . 
I 7 HOH 320 1020 20  HOH HOH A . 
I 7 HOH 321 1021 509 HOH HOH A . 
I 7 HOH 322 1022 380 HOH HOH A . 
I 7 HOH 323 1023 298 HOH HOH A . 
I 7 HOH 324 1024 313 HOH HOH A . 
I 7 HOH 325 1025 101 HOH HOH A . 
I 7 HOH 326 1026 49  HOH HOH A . 
I 7 HOH 327 1027 280 HOH HOH A . 
I 7 HOH 328 1028 474 HOH HOH A . 
I 7 HOH 329 1029 6   HOH HOH A . 
I 7 HOH 330 1030 331 HOH HOH A . 
I 7 HOH 331 1031 583 HOH HOH A . 
I 7 HOH 332 1032 255 HOH HOH A . 
I 7 HOH 333 1033 398 HOH HOH A . 
I 7 HOH 334 1034 79  HOH HOH A . 
I 7 HOH 335 1035 128 HOH HOH A . 
I 7 HOH 336 1036 338 HOH HOH A . 
I 7 HOH 337 1037 281 HOH HOH A . 
I 7 HOH 338 1038 575 HOH HOH A . 
I 7 HOH 339 1039 201 HOH HOH A . 
I 7 HOH 340 1040 233 HOH HOH A . 
I 7 HOH 341 1041 633 HOH HOH A . 
I 7 HOH 342 1042 214 HOH HOH A . 
I 7 HOH 343 1043 62  HOH HOH A . 
I 7 HOH 344 1044 198 HOH HOH A . 
I 7 HOH 345 1045 596 HOH HOH A . 
I 7 HOH 346 1046 314 HOH HOH A . 
I 7 HOH 347 1047 261 HOH HOH A . 
I 7 HOH 348 1048 167 HOH HOH A . 
I 7 HOH 349 1049 272 HOH HOH A . 
I 7 HOH 350 1050 316 HOH HOH A . 
I 7 HOH 351 1051 98  HOH HOH A . 
I 7 HOH 352 1052 556 HOH HOH A . 
I 7 HOH 353 1053 347 HOH HOH A . 
I 7 HOH 354 1054 97  HOH HOH A . 
I 7 HOH 355 1055 3   HOH HOH A . 
I 7 HOH 356 1056 303 HOH HOH A . 
I 7 HOH 357 1057 176 HOH HOH A . 
I 7 HOH 358 1058 444 HOH HOH A . 
I 7 HOH 359 1059 330 HOH HOH A . 
I 7 HOH 360 1060 582 HOH HOH A . 
I 7 HOH 361 1061 581 HOH HOH A . 
I 7 HOH 362 1062 27  HOH HOH A . 
I 7 HOH 363 1063 88  HOH HOH A . 
I 7 HOH 364 1064 222 HOH HOH A . 
I 7 HOH 365 1065 143 HOH HOH A . 
I 7 HOH 366 1066 469 HOH HOH A . 
I 7 HOH 367 1067 547 HOH HOH A . 
I 7 HOH 368 1068 141 HOH HOH A . 
I 7 HOH 369 1069 30  HOH HOH A . 
I 7 HOH 370 1070 178 HOH HOH A . 
I 7 HOH 371 1071 45  HOH HOH A . 
I 7 HOH 372 1072 228 HOH HOH A . 
I 7 HOH 373 1073 448 HOH HOH A . 
I 7 HOH 374 1074 387 HOH HOH A . 
I 7 HOH 375 1075 154 HOH HOH A . 
I 7 HOH 376 1076 560 HOH HOH A . 
I 7 HOH 377 1077 196 HOH HOH A . 
I 7 HOH 378 1078 109 HOH HOH A . 
I 7 HOH 379 1079 169 HOH HOH A . 
I 7 HOH 380 1080 145 HOH HOH A . 
I 7 HOH 381 1081 323 HOH HOH A . 
I 7 HOH 382 1082 103 HOH HOH A . 
I 7 HOH 383 1083 119 HOH HOH A . 
I 7 HOH 384 1084 268 HOH HOH A . 
I 7 HOH 385 1085 202 HOH HOH A . 
I 7 HOH 386 1086 351 HOH HOH A . 
I 7 HOH 387 1087 294 HOH HOH A . 
I 7 HOH 388 1088 433 HOH HOH A . 
I 7 HOH 389 1089 327 HOH HOH A . 
I 7 HOH 390 1090 292 HOH HOH A . 
I 7 HOH 391 1091 134 HOH HOH A . 
I 7 HOH 392 1092 420 HOH HOH A . 
I 7 HOH 393 1093 407 HOH HOH A . 
I 7 HOH 394 1094 248 HOH HOH A . 
I 7 HOH 395 1095 426 HOH HOH A . 
I 7 HOH 396 1096 226 HOH HOH A . 
I 7 HOH 397 1097 345 HOH HOH A . 
I 7 HOH 398 1098 66  HOH HOH A . 
I 7 HOH 399 1099 391 HOH HOH A . 
I 7 HOH 400 1100 496 HOH HOH A . 
I 7 HOH 401 1101 288 HOH HOH A . 
I 7 HOH 402 1102 270 HOH HOH A . 
I 7 HOH 403 1103 153 HOH HOH A . 
I 7 HOH 404 1104 614 HOH HOH A . 
I 7 HOH 405 1105 212 HOH HOH A . 
I 7 HOH 406 1106 552 HOH HOH A . 
I 7 HOH 407 1107 546 HOH HOH A . 
I 7 HOH 408 1108 221 HOH HOH A . 
I 7 HOH 409 1109 343 HOH HOH A . 
I 7 HOH 410 1110 524 HOH HOH A . 
I 7 HOH 411 1111 239 HOH HOH A . 
I 7 HOH 412 1112 429 HOH HOH A . 
I 7 HOH 413 1113 350 HOH HOH A . 
I 7 HOH 414 1114 399 HOH HOH A . 
I 7 HOH 415 1115 629 HOH HOH A . 
I 7 HOH 416 1116 619 HOH HOH A . 
I 7 HOH 417 1117 285 HOH HOH A . 
I 7 HOH 418 1118 434 HOH HOH A . 
I 7 HOH 419 1119 417 HOH HOH A . 
I 7 HOH 420 1120 550 HOH HOH A . 
I 7 HOH 421 1121 231 HOH HOH A . 
I 7 HOH 422 1122 620 HOH HOH A . 
I 7 HOH 423 1123 542 HOH HOH A . 
I 7 HOH 424 1124 361 HOH HOH A . 
I 7 HOH 425 1125 413 HOH HOH A . 
I 7 HOH 426 1126 249 HOH HOH A . 
I 7 HOH 427 1127 594 HOH HOH A . 
I 7 HOH 428 1128 250 HOH HOH A . 
I 7 HOH 429 1129 74  HOH HOH A . 
I 7 HOH 430 1130 276 HOH HOH A . 
I 7 HOH 431 1131 522 HOH HOH A . 
I 7 HOH 432 1132 232 HOH HOH A . 
I 7 HOH 433 1133 602 HOH HOH A . 
I 7 HOH 434 1134 284 HOH HOH A . 
I 7 HOH 435 1135 461 HOH HOH A . 
I 7 HOH 436 1136 421 HOH HOH A . 
I 7 HOH 437 1137 189 HOH HOH A . 
I 7 HOH 438 1138 570 HOH HOH A . 
I 7 HOH 439 1139 384 HOH HOH A . 
I 7 HOH 440 1140 630 HOH HOH A . 
I 7 HOH 441 1141 390 HOH HOH A . 
I 7 HOH 442 1142 415 HOH HOH A . 
I 7 HOH 443 1143 605 HOH HOH A . 
I 7 HOH 444 1144 256 HOH HOH A . 
I 7 HOH 445 1145 490 HOH HOH A . 
I 7 HOH 446 1146 311 HOH HOH A . 
I 7 HOH 447 1147 306 HOH HOH A . 
I 7 HOH 448 1148 366 HOH HOH A . 
I 7 HOH 449 1149 613 HOH HOH A . 
I 7 HOH 450 1150 324 HOH HOH A . 
I 7 HOH 451 1151 523 HOH HOH A . 
I 7 HOH 452 1152 604 HOH HOH A . 
I 7 HOH 453 1153 253 HOH HOH A . 
I 7 HOH 454 1154 155 HOH HOH A . 
I 7 HOH 455 1155 580 HOH HOH A . 
I 7 HOH 456 1156 510 HOH HOH A . 
I 7 HOH 457 1157 589 HOH HOH A . 
I 7 HOH 458 1158 459 HOH HOH A . 
I 7 HOH 459 1159 308 HOH HOH A . 
I 7 HOH 460 1160 468 HOH HOH A . 
I 7 HOH 461 1161 632 HOH HOH A . 
I 7 HOH 462 1162 90  HOH HOH A . 
I 7 HOH 463 1163 247 HOH HOH A . 
I 7 HOH 464 1164 617 HOH HOH A . 
I 7 HOH 465 1165 548 HOH HOH A . 
I 7 HOH 466 1166 157 HOH HOH A . 
I 7 HOH 467 1167 332 HOH HOH A . 
I 7 HOH 468 1168 342 HOH HOH A . 
I 7 HOH 469 1169 477 HOH HOH A . 
I 7 HOH 470 1170 611 HOH HOH A . 
I 7 HOH 471 1171 180 HOH HOH A . 
I 7 HOH 472 1172 411 HOH HOH A . 
I 7 HOH 473 1173 592 HOH HOH A . 
I 7 HOH 474 1174 504 HOH HOH A . 
I 7 HOH 475 1175 531 HOH HOH A . 
I 7 HOH 476 1176 265 HOH HOH A . 
I 7 HOH 477 1177 385 HOH HOH A . 
I 7 HOH 478 1178 615 HOH HOH A . 
I 7 HOH 479 1179 584 HOH HOH A . 
I 7 HOH 480 1180 305 HOH HOH A . 
I 7 HOH 481 1181 337 HOH HOH A . 
I 7 HOH 482 1182 419 HOH HOH A . 
I 7 HOH 483 1183 275 HOH HOH A . 
I 7 HOH 484 1184 543 HOH HOH A . 
I 7 HOH 485 1185 593 HOH HOH A . 
I 7 HOH 486 1186 557 HOH HOH A . 
I 7 HOH 487 1187 251 HOH HOH A . 
I 7 HOH 488 1188 554 HOH HOH A . 
I 7 HOH 489 1189 395 HOH HOH A . 
I 7 HOH 490 1190 335 HOH HOH A . 
I 7 HOH 491 1191 175 HOH HOH A . 
I 7 HOH 492 1192 163 HOH HOH A . 
I 7 HOH 493 1193 259 HOH HOH A . 
I 7 HOH 494 1194 549 HOH HOH A . 
I 7 HOH 495 1195 464 HOH HOH A . 
I 7 HOH 496 1196 609 HOH HOH A . 
I 7 HOH 497 1197 369 HOH HOH A . 
I 7 HOH 498 1198 551 HOH HOH A . 
I 7 HOH 499 1199 553 HOH HOH A . 
I 7 HOH 500 1200 291 HOH HOH A . 
I 7 HOH 501 1201 427 HOH HOH A . 
I 7 HOH 502 1202 431 HOH HOH A . 
I 7 HOH 503 1203 465 HOH HOH A . 
I 7 HOH 504 1204 273 HOH HOH A . 
I 7 HOH 505 1205 499 HOH HOH A . 
I 7 HOH 506 1206 616 HOH HOH A . 
I 7 HOH 507 1207 217 HOH HOH A . 
I 7 HOH 508 1208 439 HOH HOH A . 
I 7 HOH 509 1209 574 HOH HOH A . 
I 7 HOH 510 1210 363 HOH HOH A . 
I 7 HOH 511 1211 622 HOH HOH A . 
I 7 HOH 512 1212 608 HOH HOH A . 
I 7 HOH 513 1213 503 HOH HOH A . 
I 7 HOH 514 1214 242 HOH HOH A . 
I 7 HOH 515 1215 600 HOH HOH A . 
I 7 HOH 516 1216 238 HOH HOH A . 
I 7 HOH 517 1217 513 HOH HOH A . 
I 7 HOH 518 1218 516 HOH HOH A . 
I 7 HOH 519 1219 525 HOH HOH A . 
I 7 HOH 520 1220 478 HOH HOH A . 
I 7 HOH 521 1221 389 HOH HOH A . 
I 7 HOH 522 1222 527 HOH HOH A . 
I 7 HOH 523 1223 590 HOH HOH A . 
I 7 HOH 524 1224 236 HOH HOH A . 
I 7 HOH 525 1225 621 HOH HOH A . 
I 7 HOH 526 1226 618 HOH HOH A . 
I 7 HOH 527 1227 631 HOH HOH A . 
I 7 HOH 528 1228 204 HOH HOH A . 
I 7 HOH 529 1229 564 HOH HOH A . 
I 7 HOH 530 1230 566 HOH HOH A . 
I 7 HOH 531 1231 348 HOH HOH A . 
I 7 HOH 532 1232 555 HOH HOH A . 
I 7 HOH 533 1233 634 HOH HOH A . 
I 7 HOH 534 1234 519 HOH HOH A . 
I 7 HOH 535 1235 530 HOH HOH A . 
I 7 HOH 536 1236 491 HOH HOH A . 
I 7 HOH 537 1237 360 HOH HOH A . 
I 7 HOH 538 1238 471 HOH HOH A . 
I 7 HOH 539 1239 375 HOH HOH A . 
I 7 HOH 540 1240 576 HOH HOH A . 
I 7 HOH 541 1241 218 HOH HOH A . 
I 7 HOH 542 1242 475 HOH HOH A . 
I 7 HOH 543 1243 326 HOH HOH A . 
I 7 HOH 544 1244 125 HOH HOH A . 
I 7 HOH 545 1245 569 HOH HOH A . 
I 7 HOH 546 1246 264 HOH HOH A . 
I 7 HOH 547 1247 416 HOH HOH A . 
I 7 HOH 548 1248 442 HOH HOH A . 
I 7 HOH 549 1249 514 HOH HOH A . 
I 7 HOH 550 1250 283 HOH HOH A . 
I 7 HOH 551 1251 435 HOH HOH A . 
I 7 HOH 552 1252 447 HOH HOH A . 
I 7 HOH 553 1253 532 HOH HOH A . 
I 7 HOH 554 1254 410 HOH HOH A . 
I 7 HOH 555 1255 565 HOH HOH A . 
I 7 HOH 556 1256 237 HOH HOH A . 
I 7 HOH 557 1257 278 HOH HOH A . 
I 7 HOH 558 1258 443 HOH HOH A . 
I 7 HOH 559 1259 295 HOH HOH A . 
I 7 HOH 560 1260 502 HOH HOH A . 
I 7 HOH 561 1261 517 HOH HOH A . 
I 7 HOH 562 1262 357 HOH HOH A . 
I 7 HOH 563 1263 511 HOH HOH A . 
I 7 HOH 564 1264 328 HOH HOH A . 
I 7 HOH 565 1265 396 HOH HOH A . 
I 7 HOH 566 1266 412 HOH HOH A . 
I 7 HOH 567 1267 376 HOH HOH A . 
I 7 HOH 568 1268 485 HOH HOH A . 
I 7 HOH 569 1269 462 HOH HOH A . 
I 7 HOH 570 1270 386 HOH HOH A . 
I 7 HOH 571 1271 133 HOH HOH A . 
I 7 HOH 572 1272 406 HOH HOH A . 
I 7 HOH 573 1273 456 HOH HOH A . 
I 7 HOH 574 1274 452 HOH HOH A . 
I 7 HOH 575 1275 455 HOH HOH A . 
I 7 HOH 576 1276 124 HOH HOH A . 
I 7 HOH 577 1277 325 HOH HOH A . 
I 7 HOH 578 1278 563 HOH HOH A . 
I 7 HOH 579 1279 394 HOH HOH A . 
I 7 HOH 580 1280 310 HOH HOH A . 
I 7 HOH 581 1281 307 HOH HOH A . 
I 7 HOH 582 1282 539 HOH HOH A . 
I 7 HOH 583 1283 572 HOH HOH A . 
I 7 HOH 584 1284 257 HOH HOH A . 
I 7 HOH 585 1285 299 HOH HOH A . 
I 7 HOH 586 1286 591 HOH HOH A . 
I 7 HOH 587 1287 418 HOH HOH A . 
I 7 HOH 588 1288 486 HOH HOH A . 
I 7 HOH 589 1289 488 HOH HOH A . 
I 7 HOH 590 1290 126 HOH HOH A . 
I 7 HOH 591 1291 612 HOH HOH A . 
I 7 HOH 592 1292 558 HOH HOH A . 
I 7 HOH 593 1293 628 HOH HOH A . 
I 7 HOH 594 1294 423 HOH HOH A . 
I 7 HOH 595 1295 440 HOH HOH A . 
I 7 HOH 596 1296 506 HOH HOH A . 
I 7 HOH 597 1297 225 HOH HOH A . 
I 7 HOH 598 1298 561 HOH HOH A . 
I 7 HOH 599 1299 484 HOH HOH A . 
I 7 HOH 600 1300 438 HOH HOH A . 
I 7 HOH 601 1301 377 HOH HOH A . 
I 7 HOH 602 1302 353 HOH HOH A . 
I 7 HOH 603 1303 424 HOH HOH A . 
I 7 HOH 604 1304 346 HOH HOH A . 
I 7 HOH 605 1305 460 HOH HOH A . 
I 7 HOH 606 1306 72  HOH HOH A . 
I 7 HOH 607 1307 340 HOH HOH A . 
I 7 HOH 608 1308 479 HOH HOH A . 
I 7 HOH 609 1309 199 HOH HOH A . 
I 7 HOH 610 1310 476 HOH HOH A . 
I 7 HOH 611 1311 216 HOH HOH A . 
I 7 HOH 612 1312 84  HOH HOH A . 
I 7 HOH 613 1313 358 HOH HOH A . 
I 7 HOH 614 1314 480 HOH HOH A . 
I 7 HOH 615 1315 451 HOH HOH A . 
I 7 HOH 616 1316 457 HOH HOH A . 
I 7 HOH 617 1317 400 HOH HOH A . 
I 7 HOH 618 1318 585 HOH HOH A . 
I 7 HOH 619 1319 436 HOH HOH A . 
I 7 HOH 620 1320 489 HOH HOH A . 
I 7 HOH 621 1321 487 HOH HOH A . 
I 7 HOH 622 1322 473 HOH HOH A . 
I 7 HOH 623 1323 586 HOH HOH A . 
I 7 HOH 624 1324 449 HOH HOH A . 
I 7 HOH 625 1325 518 HOH HOH A . 
I 7 HOH 626 1326 568 HOH HOH A . 
I 7 HOH 627 1327 453 HOH HOH A . 
I 7 HOH 628 1328 529 HOH HOH A . 
I 7 HOH 629 1329 603 HOH HOH A . 
I 7 HOH 630 1330 624 HOH HOH A . 
I 7 HOH 631 1331 500 HOH HOH A . 
I 7 HOH 632 1332 472 HOH HOH A . 
I 7 HOH 633 1333 595 HOH HOH A . 
I 7 HOH 634 1334 501 HOH HOH A . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 A GLY 2   ? N   ? A GLY 7   N   
2  1 Y 1 A GLU 30  ? CD  ? A GLU 35  CD  
3  1 Y 1 A GLU 30  ? OE1 ? A GLU 35  OE1 
4  1 Y 1 A GLU 30  ? OE2 ? A GLU 35  OE2 
5  1 Y 1 A ARG 131 ? CG  ? A ARG 116 CG  
6  1 Y 1 A ARG 131 ? CD  ? A ARG 116 CD  
7  1 Y 1 A ARG 131 ? NE  ? A ARG 116 NE  
8  1 Y 1 A ARG 131 ? CZ  ? A ARG 116 CZ  
9  1 Y 1 A ARG 131 ? NH1 ? A ARG 116 NH1 
10 1 Y 1 A ARG 131 ? NH2 ? A ARG 116 NH2 
11 1 Y 1 A ASP 136 ? OD1 ? A ASP 121 OD1 
12 1 Y 1 A ASP 136 ? OD2 ? A ASP 121 OD2 
13 1 Y 1 A LYS 201 ? CG  ? A LYS 186 CG  
14 1 Y 1 A LYS 201 ? CD  ? A LYS 186 CD  
15 1 Y 1 A LYS 201 ? CE  ? A LYS 186 CE  
16 1 Y 1 A LYS 201 ? NZ  ? A LYS 186 NZ  
17 1 Y 1 A ARG 355 ? CG  ? A ARG 340 CG  
18 1 Y 1 A ARG 355 ? CD  ? A ARG 340 CD  
19 1 Y 1 A ARG 355 ? NE  ? A ARG 340 NE  
20 1 Y 1 A ARG 355 ? CZ  ? A ARG 340 CZ  
21 1 Y 1 A ARG 355 ? NH1 ? A ARG 340 NH1 
22 1 Y 1 A ARG 355 ? NH2 ? A ARG 340 NH2 
23 1 Y 1 A VAL 460 ? CG1 ? A VAL 433 CG1 
24 1 Y 1 A VAL 460 ? CG2 ? A VAL 433 CG2 
25 1 Y 1 A LYS 562 ? CD  ? A LYS 458 CD  
26 1 Y 1 A LYS 562 ? CE  ? A LYS 458 CE  
27 1 Y 1 A LYS 562 ? NZ  ? A LYS 458 NZ  
28 1 Y 1 A GLN 586 ? CG  ? A GLN 482 CG  
29 1 Y 1 A GLN 586 ? CD  ? A GLN 482 CD  
30 1 Y 1 A GLN 586 ? OE1 ? A GLN 482 OE1 
31 1 Y 1 A GLN 586 ? NE2 ? A GLN 482 NE2 
32 1 Y 1 A MET 587 ? SD  ? A MET 483 SD  
33 1 Y 1 A MET 587 ? CE  ? A MET 483 CE  
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? REFMAC   ? ? ? 5.8.0419            1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? HKL-2000 ? ? ? 722                 2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? HKL-2000 ? ? ? 722                 3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? MOLREP   ? ? ? '11.0 /22.07.2010/' 4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8VA5 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     49.057 
_cell.length_a_esd                 ? 
_cell.length_b                     80.034 
_cell.length_b_esd                 ? 
_cell.length_c                     124.823 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        4 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8VA5 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                19 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 21 21 21' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8VA5 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.24 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          45.16 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '0.2 M lithium sulfate, 0.1 M HEPES, pH 7.5, 25% (w/v) PEG-3,350' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            285 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     CCD 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'MARMOSAIC 300 mm CCD' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2023-04-08 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.97857 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'APS BEAMLINE 21-ID-G' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.97857 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   21-ID-G 
_diffrn_source.pdbx_synchrotron_site       APS 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       8VA5 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              1.3 
_reflns.d_resolution_low                               50 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     120002 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           98.9 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                6.6 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          24.51 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   ? 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.133 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    1.30 
_reflns_shell.d_res_low                                     1.32 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           2.03 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             0 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               4.9 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  ? 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          96.1 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  0.981 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            0.728 
_refine.aniso_B[1][2]                            -0.000 
_refine.aniso_B[1][3]                            0.000 
_refine.aniso_B[2][2]                            0.372 
_refine.aniso_B[2][3]                            -0.000 
_refine.aniso_B[3][3]                            -1.100 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               13.487 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               0.973 
_refine.correlation_coeff_Fo_to_Fc_free          0.966 
_refine.details                                  'Hydrogens have been added in their riding positions' 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8VA5 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            1.300 
_refine.ls_d_res_low                             26.344 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     119911 
_refine.ls_number_reflns_R_free                  6193 
_refine.ls_number_reflns_R_work                  113718 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    98.737 
_refine.ls_percent_reflns_R_free                 5.165 
_refine.ls_R_factor_all                          0.162 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       0.1858 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1607 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'MASK BULK SOLVENT' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               THROUGHOUT 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       0.047 
_refine.pdbx_overall_ESU_R_Free                  0.050 
_refine.pdbx_solvent_vdw_probe_radii             1.200 
_refine.pdbx_solvent_ion_probe_radii             0.800 
_refine.pdbx_solvent_shrinkage_radii             0.800 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             0.823 
_refine.overall_SU_ML                            0.034 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.pdbx_number_atoms_protein        3667 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         88 
_refine_hist.number_atoms_solvent             634 
_refine_hist.number_atoms_total               4389 
_refine_hist.d_res_high                       1.300 
_refine_hist.d_res_low                        26.344 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.012  0.012  4136 ? r_bond_refined_d               ? ? 
'X-RAY DIFFRACTION' ? 0.001  0.016  3912 ? r_bond_other_d                 ? ? 
'X-RAY DIFFRACTION' ? 2.005  1.837  5639 ? r_angle_refined_deg            ? ? 
'X-RAY DIFFRACTION' ? 0.682  1.750  9004 ? r_angle_other_deg              ? ? 
'X-RAY DIFFRACTION' ? 5.858  5.000  525  ? r_dihedral_angle_1_deg         ? ? 
'X-RAY DIFFRACTION' ? 13.412 5.909  33   ? r_dihedral_angle_2_deg         ? ? 
'X-RAY DIFFRACTION' ? 3.923  20.000 2    ? r_dihedral_angle_other_2_deg   ? ? 
'X-RAY DIFFRACTION' ? 11.748 10.000 691  ? r_dihedral_angle_3_deg         ? ? 
'X-RAY DIFFRACTION' ? 15.414 10.000 184  ? r_dihedral_angle_6_deg         ? ? 
'X-RAY DIFFRACTION' ? 0.105  0.200  612  ? r_chiral_restr                 ? ? 
'X-RAY DIFFRACTION' ? 0.002  0.200  1    ? r_chiral_restr_other           ? ? 
'X-RAY DIFFRACTION' ? 0.010  0.020  5024 ? r_gen_planes_refined           ? ? 
'X-RAY DIFFRACTION' ? 0.002  0.020  990  ? r_gen_planes_other             ? ? 
'X-RAY DIFFRACTION' ? 0.238  0.200  863  ? r_nbd_refined                  ? ? 
'X-RAY DIFFRACTION' ? 0.182  0.200  3437 ? r_symmetry_nbd_other           ? ? 
'X-RAY DIFFRACTION' ? 0.186  0.200  2014 ? r_nbtor_refined                ? ? 
'X-RAY DIFFRACTION' ? 0.075  0.200  1943 ? r_symmetry_nbtor_other         ? ? 
'X-RAY DIFFRACTION' ? 0.153  0.200  371  ? r_xyhbond_nbd_refined          ? ? 
'X-RAY DIFFRACTION' ? 0.077  0.200  2    ? r_symmetry_xyhbond_nbd_other   ? ? 
'X-RAY DIFFRACTION' ? 0.202  0.200  22   ? r_symmetry_nbd_refined         ? ? 
'X-RAY DIFFRACTION' ? 0.207  0.200  102  ? r_nbd_other                    ? ? 
'X-RAY DIFFRACTION' ? 0.169  0.200  44   ? r_symmetry_xyhbond_nbd_refined ? ? 
'X-RAY DIFFRACTION' ? 1.517  1.278  2018 ? r_mcbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 1.517  1.278  2018 ? r_mcbond_other                 ? ? 
'X-RAY DIFFRACTION' ? 2.272  2.296  2570 ? r_mcangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 2.272  2.297  2571 ? r_mcangle_other                ? ? 
'X-RAY DIFFRACTION' ? 2.595  1.515  2118 ? r_scbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 2.594  1.516  2119 ? r_scbond_other                 ? ? 
'X-RAY DIFFRACTION' ? 3.930  2.651  3069 ? r_scangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 3.929  2.652  3070 ? r_scangle_other                ? ? 
'X-RAY DIFFRACTION' ? 5.490  17.627 4975 ? r_lrange_it                    ? ? 
'X-RAY DIFFRACTION' ? 5.489  17.628 4976 ? r_lrange_other                 ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 1.300 1.334  8863 . 434 7960 94.7083  . 0.260 . . 0.259 . . . . . 0.247 . 20 . 0.954 0.950 0.276 
'X-RAY DIFFRACTION' 1.334 1.370  8630 . 445 7930 97.0452  . 0.239 . . 0.238 . . . . . 0.220 . 20 . 0.961 0.953 0.255 
'X-RAY DIFFRACTION' 1.370 1.410  8413 . 388 7809 97.4325  . 0.221 . . 0.219 . . . . . 0.200 . 20 . 0.967 0.961 0.249 
'X-RAY DIFFRACTION' 1.410 1.453  8155 . 404 7582 97.9277  . 0.205 . . 0.203 . . . . . 0.182 . 20 . 0.972 0.967 0.230 
'X-RAY DIFFRACTION' 1.453 1.500  7928 . 437 7347 98.1837  . 0.188 . . 0.186 . . . . . 0.164 . 20 . 0.976 0.969 0.210 
'X-RAY DIFFRACTION' 1.500 1.553  7669 . 374 7189 98.6178  . 0.173 . . 0.172 . . . . . 0.151 . 20 . 0.980 0.973 0.199 
'X-RAY DIFFRACTION' 1.553 1.611  7432 . 373 6998 99.1792  . 0.165 . . 0.163 . . . . . 0.143 . 20 . 0.982 0.977 0.192 
'X-RAY DIFFRACTION' 1.611 1.677  7170 . 375 6755 99.4421  . 0.156 . . 0.155 . . . . . 0.136 . 20 . 0.984 0.982 0.166 
'X-RAY DIFFRACTION' 1.677 1.751  6853 . 417 6411 99.6352  . 0.156 . . 0.154 . . . . . 0.136 . 20 . 0.985 0.978 0.185 
'X-RAY DIFFRACTION' 1.751 1.836  6578 . 326 6241 99.8328  . 0.149 . . 0.147 . . . . . 0.133 . 20 . 0.986 0.980 0.173 
'X-RAY DIFFRACTION' 1.836 1.935  6228 . 316 5908 99.9358  . 0.153 . . 0.151 . . . . . 0.138 . 20 . 0.986 0.978 0.189 
'X-RAY DIFFRACTION' 1.935 2.051  5991 . 287 5699 99.9165  . 0.150 . . 0.149 . . . . . 0.141 . 20 . 0.987 0.982 0.176 
'X-RAY DIFFRACTION' 2.051 2.192  5548 . 299 5247 99.9640  . 0.147 . . 0.146 . . . . . 0.142 . 20 . 0.987 0.983 0.167 
'X-RAY DIFFRACTION' 2.192 2.366  5244 . 246 4998 100.0000 . 0.133 . . 0.131 . . . . . 0.130 . 20 . 0.989 0.984 0.166 
'X-RAY DIFFRACTION' 2.366 2.590  4848 . 268 4580 100.0000 . 0.138 . . 0.137 . . . . . 0.138 . 20 . 0.988 0.983 0.162 
'X-RAY DIFFRACTION' 2.590 2.892  4382 . 197 4185 100.0000 . 0.151 . . 0.150 . . . . . 0.155 . 20 . 0.986 0.980 0.181 
'X-RAY DIFFRACTION' 2.892 3.333  3898 . 211 3687 100.0000 . 0.156 . . 0.153 . . . . . 0.163 . 20 . 0.986 0.976 0.205 
'X-RAY DIFFRACTION' 3.333 4.066  3343 . 164 3179 100.0000 . 0.141 . . 0.140 . . . . . 0.156 . 20 . 0.988 0.987 0.149 
'X-RAY DIFFRACTION' 4.066 5.683  2639 . 133 2506 100.0000 . 0.159 . . 0.159 . . . . . 0.182 . 20 . 0.988 0.990 0.168 
'X-RAY DIFFRACTION' 5.683 26.344 1614 . 99  1508 99.5663  . 0.221 . . 0.220 . . . . . 0.258 . 20 . 0.979 0.973 0.226 
# 
_struct.entry_id                     8VA5 
_struct.title                        'Menin mutant - T349M in complex with Ziftomenib (KO-539)' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8VA5 
_struct_keywords.text            'PROTEIN BINDING' 
_struct_keywords.pdbx_keywords   'PROTEIN BINDING' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
E N N 3 ? 
F N N 5 ? 
G N N 6 ? 
H N N 6 ? 
I N N 7 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    MEN1_HUMAN 
_struct_ref.pdbx_db_accession          O00255 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MGLKAAQKTLFPLRSIDDVVRLFAAELGREEPDLVLLSLVLGFVEHFLAVNRVIPTNVPELTFQPSPAPDPPGGLTYFPV
ADLSIIAALYARFTAQIRGAVDLSLYPREGGVSSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFITGTKLDSSGVAFA
VVGACQALGLRDVHLALSEDHAWVVFGPNGEQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLKGSYMRCDRKMEVAFMV
CAINPSIDLHTDSLELLQLQQKLLWLLYDLGHLERYPMALGNLADLEELEPTPGRPDPLTLYHKGIASAKTYYRDEHIYP
YMYLAGYHCRNRNVREALQAWADTATVIQDYNYCREDEEIYKEFFEVANDVIPNLLKEAASLLEAGEERPGEQSQGTQSQ
GSALQDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVRQKVRIVS
;
_struct_ref.pdbx_align_begin           0 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8VA5 A 6   ? 432 ? O00255 1   ? 459 ? 1   459 
2 1 8VA5 A 433 ? 489 ? O00255 537 ? 593 ? 460 593 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8VA5 GLY A 1   ? UNP O00255 ?   ?   'expression tag'      -4  1  
1 8VA5 GLY A 2   ? UNP O00255 ?   ?   'expression tag'      -3  2  
1 8VA5 SER A 3   ? UNP O00255 ?   ?   'expression tag'      -2  3  
1 8VA5 SER A 4   ? UNP O00255 ?   ?   'expression tag'      -1  4  
1 8VA5 SER A 5   ? UNP O00255 ?   ?   'expression tag'      0   5  
1 8VA5 ?   A ?   ? UNP O00255 ILE 54  deletion              ?   6  
1 8VA5 ?   A ?   ? UNP O00255 PRO 55  deletion              ?   7  
1 8VA5 ?   A ?   ? UNP O00255 THR 56  deletion              ?   8  
1 8VA5 ?   A ?   ? UNP O00255 ASN 57  deletion              ?   9  
1 8VA5 ?   A ?   ? UNP O00255 VAL 58  deletion              ?   10 
1 8VA5 ?   A ?   ? UNP O00255 PRO 59  deletion              ?   11 
1 8VA5 ?   A ?   ? UNP O00255 GLU 60  deletion              ?   12 
1 8VA5 ?   A ?   ? UNP O00255 LEU 61  deletion              ?   13 
1 8VA5 ?   A ?   ? UNP O00255 THR 62  deletion              ?   14 
1 8VA5 ?   A ?   ? UNP O00255 PHE 63  deletion              ?   15 
1 8VA5 ?   A ?   ? UNP O00255 GLN 64  deletion              ?   16 
1 8VA5 ?   A ?   ? UNP O00255 PRO 65  deletion              ?   17 
1 8VA5 ?   A ?   ? UNP O00255 SER 66  deletion              ?   18 
1 8VA5 ?   A ?   ? UNP O00255 PRO 67  deletion              ?   19 
1 8VA5 ?   A ?   ? UNP O00255 ALA 68  deletion              ?   20 
1 8VA5 ?   A ?   ? UNP O00255 PRO 69  deletion              ?   21 
1 8VA5 ?   A ?   ? UNP O00255 ASP 70  deletion              ?   22 
1 8VA5 ?   A ?   ? UNP O00255 PRO 71  deletion              ?   23 
1 8VA5 ?   A ?   ? UNP O00255 PRO 72  deletion              ?   24 
1 8VA5 ?   A ?   ? UNP O00255 GLY 73  deletion              ?   25 
1 8VA5 MET A 329 ? UNP O00255 THR 344 'engineered mutation' 344 26 
1 8VA5 ?   A ?   ? UNP O00255 GLU 387 deletion              ?   27 
1 8VA5 ?   A ?   ? UNP O00255 GLU 388 deletion              ?   28 
1 8VA5 ?   A ?   ? UNP O00255 ARG 389 deletion              ?   29 
1 8VA5 ?   A ?   ? UNP O00255 PRO 390 deletion              ?   30 
1 8VA5 ?   A ?   ? UNP O00255 GLY 391 deletion              ?   31 
1 8VA5 ?   A ?   ? UNP O00255 GLU 392 deletion              ?   32 
1 8VA5 ?   A ?   ? UNP O00255 GLN 393 deletion              ?   33 
1 8VA5 ?   A ?   ? UNP O00255 SER 394 deletion              ?   34 
1 8VA5 ?   A ?   ? UNP O00255 GLN 395 deletion              ?   35 
1 8VA5 ?   A ?   ? UNP O00255 GLY 396 deletion              ?   36 
1 8VA5 ?   A ?   ? UNP O00255 THR 397 deletion              ?   37 
1 8VA5 ?   A ?   ? UNP O00255 GLN 398 deletion              ?   38 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       PISA 
_pdbx_struct_assembly.oligomeric_details   monomeric 
_pdbx_struct_assembly.oligomeric_count     1 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 1150  ? 
1 MORE         9     ? 
1 'SSA (A^2)'  21010 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 LYS A 9   ? THR A 14  ? LYS A 4   THR A 9   1 ? 6  
HELX_P HELX_P2  AA2 SER A 20  ? GLY A 33  ? SER A 15  GLY A 28  1 ? 14 
HELX_P HELX_P3  AA3 ASP A 38  ? VAL A 55  ? ASP A 33  VAL A 50  1 ? 18 
HELX_P HELX_P4  AA4 ASP A 67  ? VAL A 86  ? ASP A 82  VAL A 101 1 ? 20 
HELX_P HELX_P5  AA5 ASP A 87  ? TYR A 91  ? ASP A 102 TYR A 106 5 ? 5  
HELX_P HELX_P6  AA6 ARG A 93  ? VAL A 97  ? ARG A 108 VAL A 112 5 ? 5  
HELX_P HELX_P7  AA7 SER A 99  ? SER A 113 ? SER A 114 SER A 128 1 ? 15 
HELX_P HELX_P8  AA8 SER A 127 ? THR A 135 ? SER A 142 THR A 150 1 ? 9  
HELX_P HELX_P9  AA9 ASP A 138 ? LEU A 153 ? ASP A 153 LEU A 168 1 ? 16 
HELX_P HELX_P10 AB1 GLY A 172 ? GLU A 176 ? GLY A 187 GLU A 191 5 ? 5  
HELX_P HELX_P11 AB2 VAL A 196 ? GLU A 202 ? VAL A 211 GLU A 217 1 ? 7  
HELX_P HELX_P12 AB3 SER A 204 ? SER A 211 ? SER A 219 SER A 226 5 ? 8  
HELX_P HELX_P13 AB4 ASP A 216 ? ALA A 227 ? ASP A 231 ALA A 242 1 ? 12 
HELX_P HELX_P14 AB5 SER A 238 ? LEU A 255 ? SER A 253 LEU A 270 1 ? 18 
HELX_P HELX_P15 AB6 TYR A 261 ? GLU A 275 ? TYR A 276 GLU A 290 1 ? 15 
HELX_P HELX_P16 AB7 ASP A 282 ? TYR A 298 ? ASP A 297 TYR A 313 1 ? 17 
HELX_P HELX_P17 AB8 ILE A 303 ? ASN A 316 ? ILE A 318 ASN A 331 1 ? 14 
HELX_P HELX_P18 AB9 ASN A 318 ? GLN A 334 ? ASN A 333 GLN A 349 1 ? 17 
HELX_P HELX_P19 AC1 ASP A 342 ? ASP A 355 ? ASP A 357 ASP A 370 1 ? 14 
HELX_P HELX_P20 AC2 ASP A 355 ? ALA A 370 ? ASP A 370 ALA A 385 1 ? 16 
HELX_P HELX_P21 AC3 SER A 375 ? GLN A 378 ? SER A 402 GLN A 405 5 ? 4  
HELX_P HELX_P22 AC4 ASP A 379 ? GLU A 398 ? ASP A 406 GLU A 425 1 ? 20 
HELX_P HELX_P23 AC5 HIS A 406 ? ARG A 419 ? HIS A 433 ARG A 446 1 ? 14 
HELX_P HELX_P24 AC6 GLU A 421 ? GLN A 426 ? GLU A 448 GLN A 453 1 ? 6  
HELX_P HELX_P25 AC7 SER A 451 ? LYS A 458 ? SER A 555 LYS A 562 1 ? 8  
HELX_P HELX_P26 AC8 GLU A 459 ? LEU A 461 ? GLU A 563 LEU A 565 5 ? 3  
HELX_P HELX_P27 AC9 ASN A 467 ? ALA A 477 ? ASN A 571 ALA A 581 1 ? 11 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
_struct_mon_prot_cis.pdbx_id                1 
_struct_mon_prot_cis.label_comp_id          PHE 
_struct_mon_prot_cis.label_seq_id           16 
_struct_mon_prot_cis.label_asym_id          A 
_struct_mon_prot_cis.label_alt_id           . 
_struct_mon_prot_cis.pdbx_PDB_ins_code      ? 
_struct_mon_prot_cis.auth_comp_id           PHE 
_struct_mon_prot_cis.auth_seq_id            11 
_struct_mon_prot_cis.auth_asym_id           A 
_struct_mon_prot_cis.pdbx_label_comp_id_2   PRO 
_struct_mon_prot_cis.pdbx_label_seq_id_2    17 
_struct_mon_prot_cis.pdbx_label_asym_id_2   A 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2    ? 
_struct_mon_prot_cis.pdbx_auth_comp_id_2    PRO 
_struct_mon_prot_cis.pdbx_auth_seq_id_2     12 
_struct_mon_prot_cis.pdbx_auth_asym_id_2    A 
_struct_mon_prot_cis.pdbx_PDB_model_num     1 
_struct_mon_prot_cis.pdbx_omega_angle       -1.04 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 4 ? 
AA2 ? 2 ? 
AA3 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA3 1 2 ? parallel      
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 GLN A 177 ? ALA A 179 ? GLN A 192 ALA A 194 
AA1 2 ALA A 167 ? PHE A 171 ? ALA A 182 PHE A 186 
AA1 3 HIS A 159 ? LEU A 162 ? HIS A 174 LEU A 177 
AA1 4 MET A 213 ? ARG A 214 ? MET A 228 ARG A 229 
AA2 1 SER A 231 ? ASP A 233 ? SER A 246 ASP A 248 
AA2 2 THR A 236 ? ASP A 237 ? THR A 251 ASP A 252 
AA3 1 ARG A 429 ? ILE A 430 ? ARG A 456 ILE A 457 
AA3 2 VAL A 446 ? LEU A 447 ? VAL A 550 LEU A 551 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O ALA A 179 ? O ALA A 194 N VAL A 169 ? N VAL A 184 
AA1 2 3 O TRP A 168 ? O TRP A 183 N ALA A 161 ? N ALA A 176 
AA1 3 4 N LEU A 162 ? N LEU A 177 O MET A 213 ? O MET A 228 
AA2 1 2 N ILE A 232 ? N ILE A 247 O THR A 236 ? O THR A 251 
AA3 1 2 N ARG A 429 ? N ARG A 456 O LEU A 447 ? O LEU A 551 
# 
_pdbx_entry_details.entry_id                   8VA5 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 HD1 A HIS 433 ? ? H A GLY 435 ? ? 1.31 
2 1 O   A CYS 329 ? B H A ARG 332 ? ? 1.51 
3 1 H   A GLY 202 ? ? O A HOH 715 ? ? 1.60 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1  1 NE A ARG 14  ? ? CZ A ARG 14  ? ? NH1 A ARG 14  ? ? 123.44 120.30 3.14   0.50 N 
2  1 NE A ARG 29  ? B CZ A ARG 29  ? B NH1 A ARG 29  ? B 116.68 120.30 -3.62  0.50 N 
3  1 NE A ARG 92  ? A CZ A ARG 92  ? A NH1 A ARG 92  ? A 124.65 120.30 4.35   0.50 N 
4  1 NE A ARG 207 ? ? CZ A ARG 207 ? ? NH1 A ARG 207 ? ? 123.59 120.30 3.29   0.50 N 
5  1 NE A ARG 207 ? ? CZ A ARG 207 ? ? NH2 A ARG 207 ? ? 113.97 120.30 -6.33  0.50 N 
6  1 NE A ARG 218 ? ? CZ A ARG 218 ? ? NH1 A ARG 218 ? ? 116.39 120.30 -3.91  0.50 N 
7  1 CG A MET 322 ? B SD A MET 322 ? B CE  A MET 322 ? B 81.30  100.20 -18.90 1.60 N 
8  1 CB A CYS 329 ? C CA A CYS 329 ? C C   A CYS 329 ? C 119.24 111.50 7.74   1.20 N 
9  1 N  A ARG 335 ? A CA A ARG 335 ? A CB  A ARG 335 ? A 98.28  110.60 -12.32 1.80 N 
10 1 CG A ARG 335 ? B CD A ARG 335 ? B NE  A ARG 335 ? B 96.99  111.80 -14.81 2.10 N 
11 1 NE A ARG 335 ? B CZ A ARG 335 ? B NH2 A ARG 335 ? B 114.68 120.30 -5.62  0.50 N 
12 1 CG A MET 344 ? A SD A MET 344 ? A CE  A MET 344 ? A 89.75  100.20 -10.45 1.60 N 
13 1 CB A LYS 576 ? B CA A LYS 576 ? B C   A LYS 576 ? B 123.08 110.40 12.68  2.00 N 
14 1 CB A ALA 581 ? ? CA A ALA 581 ? ? C   A ALA 581 ? ? 123.68 110.10 13.58  1.50 N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 TYR A 77  ? ? -158.64 -65.44 
2 1 ASP A 180 ? ? -142.39 13.51  
3 1 SER A 226 ? ? -89.97  46.15  
4 1 ARG A 355 ? A -38.26  125.64 
5 1 GLU A 356 ? A 93.64   2.96   
6 1 ASP A 370 ? ? -136.00 -56.47 
# 
loop_
_pdbx_validate_planes.id 
_pdbx_validate_planes.PDB_model_num 
_pdbx_validate_planes.auth_comp_id 
_pdbx_validate_planes.auth_asym_id 
_pdbx_validate_planes.auth_seq_id 
_pdbx_validate_planes.PDB_ins_code 
_pdbx_validate_planes.label_alt_id 
_pdbx_validate_planes.rmsd 
_pdbx_validate_planes.type 
1 1 ARG A 207 ? ? 0.073 'SIDE CHAIN' 
2 1 ARG A 335 ? A 0.265 'SIDE CHAIN' 
# 
_pdbx_distant_solvent_atoms.id                                1 
_pdbx_distant_solvent_atoms.PDB_model_num                     1 
_pdbx_distant_solvent_atoms.auth_atom_id                      O 
_pdbx_distant_solvent_atoms.label_alt_id                      ? 
_pdbx_distant_solvent_atoms.auth_asym_id                      A 
_pdbx_distant_solvent_atoms.auth_comp_id                      HOH 
_pdbx_distant_solvent_atoms.auth_seq_id                       1334 
_pdbx_distant_solvent_atoms.PDB_ins_code                      ? 
_pdbx_distant_solvent_atoms.neighbor_macromolecule_distance   7.11 
_pdbx_distant_solvent_atoms.neighbor_ligand_distance          . 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A GLY -4  ? A GLY 1   
2  1 Y 1 A GLY -3  ? A GLY 2   
3  1 Y 1 A SER -2  ? A SER 3   
4  1 Y 1 A SER -1  ? A SER 4   
5  1 Y 1 A SER 0   ? A SER 5   
6  1 Y 1 A MET 1   ? A MET 6   
7  1 Y 1 A PRO 538 ? A PRO 434 
8  1 Y 1 A ALA 539 ? A ALA 435 
9  1 Y 1 A PRO 540 ? A PRO 436 
10 1 Y 1 A THR 541 ? A THR 437 
11 1 Y 1 A ALA 542 ? A ALA 438 
12 1 Y 1 A SER 543 ? A SER 439 
13 1 Y 1 A PRO 544 ? A PRO 440 
14 1 Y 1 A PRO 545 ? A PRO 441 
15 1 Y 1 A PRO 546 ? A PRO 442 
16 1 Y 1 A GLU 547 ? A GLU 443 
17 1 Y 1 A GLY 548 ? A GLY 444 
18 1 Y 1 A LYS 589 ? A LYS 485 
19 1 Y 1 A GLN 590 ? A GLN 486 
20 1 Y 1 A LYS 591 ? A LYS 487 
21 1 Y 1 A VAL 592 ? A VAL 488 
22 1 Y 1 A SER 593 ? A SER 489 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
DMS S    S N N 88  
DMS O    O N N 89  
DMS C1   C N N 90  
DMS C2   C N N 91  
DMS H11  H N N 92  
DMS H12  H N N 93  
DMS H13  H N N 94  
DMS H21  H N N 95  
DMS H22  H N N 96  
DMS H23  H N N 97  
EDO C1   C N N 98  
EDO O1   O N N 99  
EDO C2   C N N 100 
EDO O2   O N N 101 
EDO H11  H N N 102 
EDO H12  H N N 103 
EDO HO1  H N N 104 
EDO H21  H N N 105 
EDO H22  H N N 106 
EDO HO2  H N N 107 
GLN N    N N N 108 
GLN CA   C N S 109 
GLN C    C N N 110 
GLN O    O N N 111 
GLN CB   C N N 112 
GLN CG   C N N 113 
GLN CD   C N N 114 
GLN OE1  O N N 115 
GLN NE2  N N N 116 
GLN OXT  O N N 117 
GLN H    H N N 118 
GLN H2   H N N 119 
GLN HA   H N N 120 
GLN HB2  H N N 121 
GLN HB3  H N N 122 
GLN HG2  H N N 123 
GLN HG3  H N N 124 
GLN HE21 H N N 125 
GLN HE22 H N N 126 
GLN HXT  H N N 127 
GLU N    N N N 128 
GLU CA   C N S 129 
GLU C    C N N 130 
GLU O    O N N 131 
GLU CB   C N N 132 
GLU CG   C N N 133 
GLU CD   C N N 134 
GLU OE1  O N N 135 
GLU OE2  O N N 136 
GLU OXT  O N N 137 
GLU H    H N N 138 
GLU H2   H N N 139 
GLU HA   H N N 140 
GLU HB2  H N N 141 
GLU HB3  H N N 142 
GLU HG2  H N N 143 
GLU HG3  H N N 144 
GLU HE2  H N N 145 
GLU HXT  H N N 146 
GLY N    N N N 147 
GLY CA   C N N 148 
GLY C    C N N 149 
GLY O    O N N 150 
GLY OXT  O N N 151 
GLY H    H N N 152 
GLY H2   H N N 153 
GLY HA2  H N N 154 
GLY HA3  H N N 155 
GLY HXT  H N N 156 
HIS N    N N N 157 
HIS CA   C N S 158 
HIS C    C N N 159 
HIS O    O N N 160 
HIS CB   C N N 161 
HIS CG   C Y N 162 
HIS ND1  N Y N 163 
HIS CD2  C Y N 164 
HIS CE1  C Y N 165 
HIS NE2  N Y N 166 
HIS OXT  O N N 167 
HIS H    H N N 168 
HIS H2   H N N 169 
HIS HA   H N N 170 
HIS HB2  H N N 171 
HIS HB3  H N N 172 
HIS HD1  H N N 173 
HIS HD2  H N N 174 
HIS HE1  H N N 175 
HIS HE2  H N N 176 
HIS HXT  H N N 177 
HOH O    O N N 178 
HOH H1   H N N 179 
HOH H2   H N N 180 
ILE N    N N N 181 
ILE CA   C N S 182 
ILE C    C N N 183 
ILE O    O N N 184 
ILE CB   C N S 185 
ILE CG1  C N N 186 
ILE CG2  C N N 187 
ILE CD1  C N N 188 
ILE OXT  O N N 189 
ILE H    H N N 190 
ILE H2   H N N 191 
ILE HA   H N N 192 
ILE HB   H N N 193 
ILE HG12 H N N 194 
ILE HG13 H N N 195 
ILE HG21 H N N 196 
ILE HG22 H N N 197 
ILE HG23 H N N 198 
ILE HD11 H N N 199 
ILE HD12 H N N 200 
ILE HD13 H N N 201 
ILE HXT  H N N 202 
K5O C1   C N N 203 
K5O N1   N N N 204 
K5O C2   C Y N 205 
K5O N2   N Y N 206 
K5O C3   C Y N 207 
K5O N3   N N N 208 
K5O C4   C N N 209 
K5O C5   C N N 210 
K5O C6   C N N 211 
K5O N4   N N N 212 
K5O C7   C N N 213 
K5O C8   C Y N 214 
K5O C9   C Y N 215 
K5O C10  C Y N 216 
K5O C11  C Y N 217 
K5O N5   N Y N 218 
K5O C12  C N N 219 
K5O C13  C N S 220 
K5O C14  C N N 221 
K5O N6   N N N 222 
K5O C15  C N N 223 
K5O C16  C N N 224 
K5O N7   N N N 225 
K5O C17  C N N 226 
K5O C18  C N N 227 
K5O S1   S N N 228 
K5O C19  C N N 229 
K5O O1   O N N 230 
K5O O2   O N N 231 
K5O C20  C Y N 232 
K5O C21  C Y N 233 
K5O C22  C Y N 234 
K5O C23  C Y N 235 
K5O C24  C N N 236 
K5O C25  C N N 237 
K5O N8   N N N 238 
K5O C26  C N N 239 
K5O C27  C N N 240 
K5O C28  C Y N 241 
K5O C29  C Y N 242 
K5O C30  C Y N 243 
K5O C31  C N N 244 
K5O C32  C N N 245 
K5O F1   F N N 246 
K5O F2   F N N 247 
K5O F3   F N N 248 
K5O S2   S Y N 249 
K5O C33  C Y N 250 
K5O N9   N Y N 251 
K5O H1   H N N 252 
K5O H2   H N N 253 
K5O H3   H N N 254 
K5O H4   H N N 255 
K5O H5   H N N 256 
K5O H6   H N N 257 
K5O H7   H N N 258 
K5O H8   H N N 259 
K5O H9   H N N 260 
K5O H10  H N N 261 
K5O H12  H N N 262 
K5O H13  H N N 263 
K5O H14  H N N 264 
K5O H15  H N N 265 
K5O H16  H N N 266 
K5O H17  H N N 267 
K5O H18  H N N 268 
K5O H19  H N N 269 
K5O H20  H N N 270 
K5O H21  H N N 271 
K5O H23  H N N 272 
K5O H24  H N N 273 
K5O H25  H N N 274 
K5O H26  H N N 275 
K5O H27  H N N 276 
K5O H28  H N N 277 
K5O H29  H N N 278 
K5O H30  H N N 279 
K5O H31  H N N 280 
K5O H32  H N N 281 
K5O H33  H N N 282 
K5O H34  H N N 283 
K5O H35  H N N 284 
K5O H36  H N N 285 
K5O H37  H N N 286 
K5O H38  H N N 287 
K5O H39  H N N 288 
K5O H40  H N N 289 
K5O H41  H N N 290 
K5O H42  H N N 291 
K5O H43  H N N 292 
K5O H44  H N N 293 
LEU N    N N N 294 
LEU CA   C N S 295 
LEU C    C N N 296 
LEU O    O N N 297 
LEU CB   C N N 298 
LEU CG   C N N 299 
LEU CD1  C N N 300 
LEU CD2  C N N 301 
LEU OXT  O N N 302 
LEU H    H N N 303 
LEU H2   H N N 304 
LEU HA   H N N 305 
LEU HB2  H N N 306 
LEU HB3  H N N 307 
LEU HG   H N N 308 
LEU HD11 H N N 309 
LEU HD12 H N N 310 
LEU HD13 H N N 311 
LEU HD21 H N N 312 
LEU HD22 H N N 313 
LEU HD23 H N N 314 
LEU HXT  H N N 315 
LYS N    N N N 316 
LYS CA   C N S 317 
LYS C    C N N 318 
LYS O    O N N 319 
LYS CB   C N N 320 
LYS CG   C N N 321 
LYS CD   C N N 322 
LYS CE   C N N 323 
LYS NZ   N N N 324 
LYS OXT  O N N 325 
LYS H    H N N 326 
LYS H2   H N N 327 
LYS HA   H N N 328 
LYS HB2  H N N 329 
LYS HB3  H N N 330 
LYS HG2  H N N 331 
LYS HG3  H N N 332 
LYS HD2  H N N 333 
LYS HD3  H N N 334 
LYS HE2  H N N 335 
LYS HE3  H N N 336 
LYS HZ1  H N N 337 
LYS HZ2  H N N 338 
LYS HZ3  H N N 339 
LYS HXT  H N N 340 
MET N    N N N 341 
MET CA   C N S 342 
MET C    C N N 343 
MET O    O N N 344 
MET CB   C N N 345 
MET CG   C N N 346 
MET SD   S N N 347 
MET CE   C N N 348 
MET OXT  O N N 349 
MET H    H N N 350 
MET H2   H N N 351 
MET HA   H N N 352 
MET HB2  H N N 353 
MET HB3  H N N 354 
MET HG2  H N N 355 
MET HG3  H N N 356 
MET HE1  H N N 357 
MET HE2  H N N 358 
MET HE3  H N N 359 
MET HXT  H N N 360 
PEG C1   C N N 361 
PEG O1   O N N 362 
PEG C2   C N N 363 
PEG O2   O N N 364 
PEG C3   C N N 365 
PEG C4   C N N 366 
PEG O4   O N N 367 
PEG H11  H N N 368 
PEG H12  H N N 369 
PEG HO1  H N N 370 
PEG H21  H N N 371 
PEG H22  H N N 372 
PEG H31  H N N 373 
PEG H32  H N N 374 
PEG H41  H N N 375 
PEG H42  H N N 376 
PEG HO4  H N N 377 
PG4 O1   O N N 378 
PG4 C1   C N N 379 
PG4 C2   C N N 380 
PG4 O2   O N N 381 
PG4 C3   C N N 382 
PG4 C4   C N N 383 
PG4 O3   O N N 384 
PG4 C5   C N N 385 
PG4 C6   C N N 386 
PG4 O4   O N N 387 
PG4 C7   C N N 388 
PG4 C8   C N N 389 
PG4 O5   O N N 390 
PG4 HO1  H N N 391 
PG4 H11  H N N 392 
PG4 H12  H N N 393 
PG4 H21  H N N 394 
PG4 H22  H N N 395 
PG4 H31  H N N 396 
PG4 H32  H N N 397 
PG4 H41  H N N 398 
PG4 H42  H N N 399 
PG4 H51  H N N 400 
PG4 H52  H N N 401 
PG4 H61  H N N 402 
PG4 H62  H N N 403 
PG4 H71  H N N 404 
PG4 H72  H N N 405 
PG4 H81  H N N 406 
PG4 H82  H N N 407 
PG4 HO5  H N N 408 
PHE N    N N N 409 
PHE CA   C N S 410 
PHE C    C N N 411 
PHE O    O N N 412 
PHE CB   C N N 413 
PHE CG   C Y N 414 
PHE CD1  C Y N 415 
PHE CD2  C Y N 416 
PHE CE1  C Y N 417 
PHE CE2  C Y N 418 
PHE CZ   C Y N 419 
PHE OXT  O N N 420 
PHE H    H N N 421 
PHE H2   H N N 422 
PHE HA   H N N 423 
PHE HB2  H N N 424 
PHE HB3  H N N 425 
PHE HD1  H N N 426 
PHE HD2  H N N 427 
PHE HE1  H N N 428 
PHE HE2  H N N 429 
PHE HZ   H N N 430 
PHE HXT  H N N 431 
PRO N    N N N 432 
PRO CA   C N S 433 
PRO C    C N N 434 
PRO O    O N N 435 
PRO CB   C N N 436 
PRO CG   C N N 437 
PRO CD   C N N 438 
PRO OXT  O N N 439 
PRO H    H N N 440 
PRO HA   H N N 441 
PRO HB2  H N N 442 
PRO HB3  H N N 443 
PRO HG2  H N N 444 
PRO HG3  H N N 445 
PRO HD2  H N N 446 
PRO HD3  H N N 447 
PRO HXT  H N N 448 
SER N    N N N 449 
SER CA   C N S 450 
SER C    C N N 451 
SER O    O N N 452 
SER CB   C N N 453 
SER OG   O N N 454 
SER OXT  O N N 455 
SER H    H N N 456 
SER H2   H N N 457 
SER HA   H N N 458 
SER HB2  H N N 459 
SER HB3  H N N 460 
SER HG   H N N 461 
SER HXT  H N N 462 
THR N    N N N 463 
THR CA   C N S 464 
THR C    C N N 465 
THR O    O N N 466 
THR CB   C N R 467 
THR OG1  O N N 468 
THR CG2  C N N 469 
THR OXT  O N N 470 
THR H    H N N 471 
THR H2   H N N 472 
THR HA   H N N 473 
THR HB   H N N 474 
THR HG1  H N N 475 
THR HG21 H N N 476 
THR HG22 H N N 477 
THR HG23 H N N 478 
THR HXT  H N N 479 
TRP N    N N N 480 
TRP CA   C N S 481 
TRP C    C N N 482 
TRP O    O N N 483 
TRP CB   C N N 484 
TRP CG   C Y N 485 
TRP CD1  C Y N 486 
TRP CD2  C Y N 487 
TRP NE1  N Y N 488 
TRP CE2  C Y N 489 
TRP CE3  C Y N 490 
TRP CZ2  C Y N 491 
TRP CZ3  C Y N 492 
TRP CH2  C Y N 493 
TRP OXT  O N N 494 
TRP H    H N N 495 
TRP H2   H N N 496 
TRP HA   H N N 497 
TRP HB2  H N N 498 
TRP HB3  H N N 499 
TRP HD1  H N N 500 
TRP HE1  H N N 501 
TRP HE3  H N N 502 
TRP HZ2  H N N 503 
TRP HZ3  H N N 504 
TRP HH2  H N N 505 
TRP HXT  H N N 506 
TYR N    N N N 507 
TYR CA   C N S 508 
TYR C    C N N 509 
TYR O    O N N 510 
TYR CB   C N N 511 
TYR CG   C Y N 512 
TYR CD1  C Y N 513 
TYR CD2  C Y N 514 
TYR CE1  C Y N 515 
TYR CE2  C Y N 516 
TYR CZ   C Y N 517 
TYR OH   O N N 518 
TYR OXT  O N N 519 
TYR H    H N N 520 
TYR H2   H N N 521 
TYR HA   H N N 522 
TYR HB2  H N N 523 
TYR HB3  H N N 524 
TYR HD1  H N N 525 
TYR HD2  H N N 526 
TYR HE1  H N N 527 
TYR HE2  H N N 528 
TYR HH   H N N 529 
TYR HXT  H N N 530 
VAL N    N N N 531 
VAL CA   C N S 532 
VAL C    C N N 533 
VAL O    O N N 534 
VAL CB   C N N 535 
VAL CG1  C N N 536 
VAL CG2  C N N 537 
VAL OXT  O N N 538 
VAL H    H N N 539 
VAL H2   H N N 540 
VAL HA   H N N 541 
VAL HB   H N N 542 
VAL HG11 H N N 543 
VAL HG12 H N N 544 
VAL HG13 H N N 545 
VAL HG21 H N N 546 
VAL HG22 H N N 547 
VAL HG23 H N N 548 
VAL HXT  H N N 549 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
DMS S   O    doub N N 83  
DMS S   C1   sing N N 84  
DMS S   C2   sing N N 85  
DMS C1  H11  sing N N 86  
DMS C1  H12  sing N N 87  
DMS C1  H13  sing N N 88  
DMS C2  H21  sing N N 89  
DMS C2  H22  sing N N 90  
DMS C2  H23  sing N N 91  
EDO C1  O1   sing N N 92  
EDO C1  C2   sing N N 93  
EDO C1  H11  sing N N 94  
EDO C1  H12  sing N N 95  
EDO O1  HO1  sing N N 96  
EDO C2  O2   sing N N 97  
EDO C2  H21  sing N N 98  
EDO C2  H22  sing N N 99  
EDO O2  HO2  sing N N 100 
GLN N   CA   sing N N 101 
GLN N   H    sing N N 102 
GLN N   H2   sing N N 103 
GLN CA  C    sing N N 104 
GLN CA  CB   sing N N 105 
GLN CA  HA   sing N N 106 
GLN C   O    doub N N 107 
GLN C   OXT  sing N N 108 
GLN CB  CG   sing N N 109 
GLN CB  HB2  sing N N 110 
GLN CB  HB3  sing N N 111 
GLN CG  CD   sing N N 112 
GLN CG  HG2  sing N N 113 
GLN CG  HG3  sing N N 114 
GLN CD  OE1  doub N N 115 
GLN CD  NE2  sing N N 116 
GLN NE2 HE21 sing N N 117 
GLN NE2 HE22 sing N N 118 
GLN OXT HXT  sing N N 119 
GLU N   CA   sing N N 120 
GLU N   H    sing N N 121 
GLU N   H2   sing N N 122 
GLU CA  C    sing N N 123 
GLU CA  CB   sing N N 124 
GLU CA  HA   sing N N 125 
GLU C   O    doub N N 126 
GLU C   OXT  sing N N 127 
GLU CB  CG   sing N N 128 
GLU CB  HB2  sing N N 129 
GLU CB  HB3  sing N N 130 
GLU CG  CD   sing N N 131 
GLU CG  HG2  sing N N 132 
GLU CG  HG3  sing N N 133 
GLU CD  OE1  doub N N 134 
GLU CD  OE2  sing N N 135 
GLU OE2 HE2  sing N N 136 
GLU OXT HXT  sing N N 137 
GLY N   CA   sing N N 138 
GLY N   H    sing N N 139 
GLY N   H2   sing N N 140 
GLY CA  C    sing N N 141 
GLY CA  HA2  sing N N 142 
GLY CA  HA3  sing N N 143 
GLY C   O    doub N N 144 
GLY C   OXT  sing N N 145 
GLY OXT HXT  sing N N 146 
HIS N   CA   sing N N 147 
HIS N   H    sing N N 148 
HIS N   H2   sing N N 149 
HIS CA  C    sing N N 150 
HIS CA  CB   sing N N 151 
HIS CA  HA   sing N N 152 
HIS C   O    doub N N 153 
HIS C   OXT  sing N N 154 
HIS CB  CG   sing N N 155 
HIS CB  HB2  sing N N 156 
HIS CB  HB3  sing N N 157 
HIS CG  ND1  sing Y N 158 
HIS CG  CD2  doub Y N 159 
HIS ND1 CE1  doub Y N 160 
HIS ND1 HD1  sing N N 161 
HIS CD2 NE2  sing Y N 162 
HIS CD2 HD2  sing N N 163 
HIS CE1 NE2  sing Y N 164 
HIS CE1 HE1  sing N N 165 
HIS NE2 HE2  sing N N 166 
HIS OXT HXT  sing N N 167 
HOH O   H1   sing N N 168 
HOH O   H2   sing N N 169 
ILE N   CA   sing N N 170 
ILE N   H    sing N N 171 
ILE N   H2   sing N N 172 
ILE CA  C    sing N N 173 
ILE CA  CB   sing N N 174 
ILE CA  HA   sing N N 175 
ILE C   O    doub N N 176 
ILE C   OXT  sing N N 177 
ILE CB  CG1  sing N N 178 
ILE CB  CG2  sing N N 179 
ILE CB  HB   sing N N 180 
ILE CG1 CD1  sing N N 181 
ILE CG1 HG12 sing N N 182 
ILE CG1 HG13 sing N N 183 
ILE CG2 HG21 sing N N 184 
ILE CG2 HG22 sing N N 185 
ILE CG2 HG23 sing N N 186 
ILE CD1 HD11 sing N N 187 
ILE CD1 HD12 sing N N 188 
ILE CD1 HD13 sing N N 189 
ILE OXT HXT  sing N N 190 
K5O O2  S1   doub N N 191 
K5O O1  S1   doub N N 192 
K5O C19 S1   sing N N 193 
K5O S1  N7   sing N N 194 
K5O N7  C17  sing N N 195 
K5O N7  C16  sing N N 196 
K5O C17 C18  sing N N 197 
K5O C24 C23  sing N N 198 
K5O C1  N1   sing N N 199 
K5O C16 C15  sing N N 200 
K5O C18 N6   sing N N 201 
K5O C21 C22  sing Y N 202 
K5O C21 C20  doub Y N 203 
K5O C23 C22  doub Y N 204 
K5O C23 C8   sing Y N 205 
K5O N1  C2   sing N N 206 
K5O C7  C8   sing N N 207 
K5O C7  N4   sing N N 208 
K5O C22 C11  sing Y N 209 
K5O C15 N6   sing N N 210 
K5O C26 N4   sing N N 211 
K5O C26 C27  sing N N 212 
K5O N8  C25  trip N N 213 
K5O C8  C9   doub Y N 214 
K5O C25 C20  sing N N 215 
K5O C20 N5   sing Y N 216 
K5O N6  C13  sing N N 217 
K5O N4  C6   sing N N 218 
K5O C2  N2   doub Y N 219 
K5O C2  N9   sing Y N 220 
K5O C11 N5   sing Y N 221 
K5O C11 C10  doub Y N 222 
K5O C27 C4   sing N N 223 
K5O N2  C3   sing Y N 224 
K5O N5  C12  sing N N 225 
K5O C9  C10  sing Y N 226 
K5O C6  C5   sing N N 227 
K5O C4  C5   sing N N 228 
K5O C4  N3   sing N N 229 
K5O C13 C12  sing N N 230 
K5O C13 C14  sing N N 231 
K5O N9  C33  doub Y N 232 
K5O C3  N3   sing N N 233 
K5O C3  C28  doub Y N 234 
K5O C33 C28  sing Y N 235 
K5O C33 S2   sing Y N 236 
K5O C28 C29  sing Y N 237 
K5O S2  C30  sing Y N 238 
K5O C29 C30  doub Y N 239 
K5O C30 C31  sing N N 240 
K5O F1  C32  sing N N 241 
K5O F2  C32  sing N N 242 
K5O C31 C32  sing N N 243 
K5O C32 F3   sing N N 244 
K5O C1  H1   sing N N 245 
K5O C1  H2   sing N N 246 
K5O C1  H3   sing N N 247 
K5O N1  H4   sing N N 248 
K5O N3  H5   sing N N 249 
K5O C4  H6   sing N N 250 
K5O C5  H7   sing N N 251 
K5O C5  H8   sing N N 252 
K5O C6  H9   sing N N 253 
K5O C6  H10  sing N N 254 
K5O C7  H12  sing N N 255 
K5O C7  H13  sing N N 256 
K5O C9  H14  sing N N 257 
K5O C10 H15  sing N N 258 
K5O C12 H16  sing N N 259 
K5O C12 H17  sing N N 260 
K5O C13 H18  sing N N 261 
K5O C14 H19  sing N N 262 
K5O C14 H20  sing N N 263 
K5O C14 H21  sing N N 264 
K5O C15 H23  sing N N 265 
K5O C15 H24  sing N N 266 
K5O C16 H25  sing N N 267 
K5O C16 H26  sing N N 268 
K5O C17 H27  sing N N 269 
K5O C17 H28  sing N N 270 
K5O C18 H29  sing N N 271 
K5O C18 H30  sing N N 272 
K5O C19 H31  sing N N 273 
K5O C19 H32  sing N N 274 
K5O C19 H33  sing N N 275 
K5O C21 H34  sing N N 276 
K5O C24 H35  sing N N 277 
K5O C24 H36  sing N N 278 
K5O C24 H37  sing N N 279 
K5O C26 H38  sing N N 280 
K5O C26 H39  sing N N 281 
K5O C27 H40  sing N N 282 
K5O C27 H41  sing N N 283 
K5O C29 H42  sing N N 284 
K5O C31 H43  sing N N 285 
K5O C31 H44  sing N N 286 
LEU N   CA   sing N N 287 
LEU N   H    sing N N 288 
LEU N   H2   sing N N 289 
LEU CA  C    sing N N 290 
LEU CA  CB   sing N N 291 
LEU CA  HA   sing N N 292 
LEU C   O    doub N N 293 
LEU C   OXT  sing N N 294 
LEU CB  CG   sing N N 295 
LEU CB  HB2  sing N N 296 
LEU CB  HB3  sing N N 297 
LEU CG  CD1  sing N N 298 
LEU CG  CD2  sing N N 299 
LEU CG  HG   sing N N 300 
LEU CD1 HD11 sing N N 301 
LEU CD1 HD12 sing N N 302 
LEU CD1 HD13 sing N N 303 
LEU CD2 HD21 sing N N 304 
LEU CD2 HD22 sing N N 305 
LEU CD2 HD23 sing N N 306 
LEU OXT HXT  sing N N 307 
LYS N   CA   sing N N 308 
LYS N   H    sing N N 309 
LYS N   H2   sing N N 310 
LYS CA  C    sing N N 311 
LYS CA  CB   sing N N 312 
LYS CA  HA   sing N N 313 
LYS C   O    doub N N 314 
LYS C   OXT  sing N N 315 
LYS CB  CG   sing N N 316 
LYS CB  HB2  sing N N 317 
LYS CB  HB3  sing N N 318 
LYS CG  CD   sing N N 319 
LYS CG  HG2  sing N N 320 
LYS CG  HG3  sing N N 321 
LYS CD  CE   sing N N 322 
LYS CD  HD2  sing N N 323 
LYS CD  HD3  sing N N 324 
LYS CE  NZ   sing N N 325 
LYS CE  HE2  sing N N 326 
LYS CE  HE3  sing N N 327 
LYS NZ  HZ1  sing N N 328 
LYS NZ  HZ2  sing N N 329 
LYS NZ  HZ3  sing N N 330 
LYS OXT HXT  sing N N 331 
MET N   CA   sing N N 332 
MET N   H    sing N N 333 
MET N   H2   sing N N 334 
MET CA  C    sing N N 335 
MET CA  CB   sing N N 336 
MET CA  HA   sing N N 337 
MET C   O    doub N N 338 
MET C   OXT  sing N N 339 
MET CB  CG   sing N N 340 
MET CB  HB2  sing N N 341 
MET CB  HB3  sing N N 342 
MET CG  SD   sing N N 343 
MET CG  HG2  sing N N 344 
MET CG  HG3  sing N N 345 
MET SD  CE   sing N N 346 
MET CE  HE1  sing N N 347 
MET CE  HE2  sing N N 348 
MET CE  HE3  sing N N 349 
MET OXT HXT  sing N N 350 
PEG C1  O1   sing N N 351 
PEG C1  C2   sing N N 352 
PEG C1  H11  sing N N 353 
PEG C1  H12  sing N N 354 
PEG O1  HO1  sing N N 355 
PEG C2  O2   sing N N 356 
PEG C2  H21  sing N N 357 
PEG C2  H22  sing N N 358 
PEG O2  C3   sing N N 359 
PEG C3  C4   sing N N 360 
PEG C3  H31  sing N N 361 
PEG C3  H32  sing N N 362 
PEG C4  O4   sing N N 363 
PEG C4  H41  sing N N 364 
PEG C4  H42  sing N N 365 
PEG O4  HO4  sing N N 366 
PG4 O1  C1   sing N N 367 
PG4 O1  HO1  sing N N 368 
PG4 C1  C2   sing N N 369 
PG4 C1  H11  sing N N 370 
PG4 C1  H12  sing N N 371 
PG4 C2  O2   sing N N 372 
PG4 C2  H21  sing N N 373 
PG4 C2  H22  sing N N 374 
PG4 O2  C3   sing N N 375 
PG4 C3  C4   sing N N 376 
PG4 C3  H31  sing N N 377 
PG4 C3  H32  sing N N 378 
PG4 C4  O3   sing N N 379 
PG4 C4  H41  sing N N 380 
PG4 C4  H42  sing N N 381 
PG4 O3  C5   sing N N 382 
PG4 C5  C6   sing N N 383 
PG4 C5  H51  sing N N 384 
PG4 C5  H52  sing N N 385 
PG4 C6  O4   sing N N 386 
PG4 C6  H61  sing N N 387 
PG4 C6  H62  sing N N 388 
PG4 O4  C7   sing N N 389 
PG4 C7  C8   sing N N 390 
PG4 C7  H71  sing N N 391 
PG4 C7  H72  sing N N 392 
PG4 C8  O5   sing N N 393 
PG4 C8  H81  sing N N 394 
PG4 C8  H82  sing N N 395 
PG4 O5  HO5  sing N N 396 
PHE N   CA   sing N N 397 
PHE N   H    sing N N 398 
PHE N   H2   sing N N 399 
PHE CA  C    sing N N 400 
PHE CA  CB   sing N N 401 
PHE CA  HA   sing N N 402 
PHE C   O    doub N N 403 
PHE C   OXT  sing N N 404 
PHE CB  CG   sing N N 405 
PHE CB  HB2  sing N N 406 
PHE CB  HB3  sing N N 407 
PHE CG  CD1  doub Y N 408 
PHE CG  CD2  sing Y N 409 
PHE CD1 CE1  sing Y N 410 
PHE CD1 HD1  sing N N 411 
PHE CD2 CE2  doub Y N 412 
PHE CD2 HD2  sing N N 413 
PHE CE1 CZ   doub Y N 414 
PHE CE1 HE1  sing N N 415 
PHE CE2 CZ   sing Y N 416 
PHE CE2 HE2  sing N N 417 
PHE CZ  HZ   sing N N 418 
PHE OXT HXT  sing N N 419 
PRO N   CA   sing N N 420 
PRO N   CD   sing N N 421 
PRO N   H    sing N N 422 
PRO CA  C    sing N N 423 
PRO CA  CB   sing N N 424 
PRO CA  HA   sing N N 425 
PRO C   O    doub N N 426 
PRO C   OXT  sing N N 427 
PRO CB  CG   sing N N 428 
PRO CB  HB2  sing N N 429 
PRO CB  HB3  sing N N 430 
PRO CG  CD   sing N N 431 
PRO CG  HG2  sing N N 432 
PRO CG  HG3  sing N N 433 
PRO CD  HD2  sing N N 434 
PRO CD  HD3  sing N N 435 
PRO OXT HXT  sing N N 436 
SER N   CA   sing N N 437 
SER N   H    sing N N 438 
SER N   H2   sing N N 439 
SER CA  C    sing N N 440 
SER CA  CB   sing N N 441 
SER CA  HA   sing N N 442 
SER C   O    doub N N 443 
SER C   OXT  sing N N 444 
SER CB  OG   sing N N 445 
SER CB  HB2  sing N N 446 
SER CB  HB3  sing N N 447 
SER OG  HG   sing N N 448 
SER OXT HXT  sing N N 449 
THR N   CA   sing N N 450 
THR N   H    sing N N 451 
THR N   H2   sing N N 452 
THR CA  C    sing N N 453 
THR CA  CB   sing N N 454 
THR CA  HA   sing N N 455 
THR C   O    doub N N 456 
THR C   OXT  sing N N 457 
THR CB  OG1  sing N N 458 
THR CB  CG2  sing N N 459 
THR CB  HB   sing N N 460 
THR OG1 HG1  sing N N 461 
THR CG2 HG21 sing N N 462 
THR CG2 HG22 sing N N 463 
THR CG2 HG23 sing N N 464 
THR OXT HXT  sing N N 465 
TRP N   CA   sing N N 466 
TRP N   H    sing N N 467 
TRP N   H2   sing N N 468 
TRP CA  C    sing N N 469 
TRP CA  CB   sing N N 470 
TRP CA  HA   sing N N 471 
TRP C   O    doub N N 472 
TRP C   OXT  sing N N 473 
TRP CB  CG   sing N N 474 
TRP CB  HB2  sing N N 475 
TRP CB  HB3  sing N N 476 
TRP CG  CD1  doub Y N 477 
TRP CG  CD2  sing Y N 478 
TRP CD1 NE1  sing Y N 479 
TRP CD1 HD1  sing N N 480 
TRP CD2 CE2  doub Y N 481 
TRP CD2 CE3  sing Y N 482 
TRP NE1 CE2  sing Y N 483 
TRP NE1 HE1  sing N N 484 
TRP CE2 CZ2  sing Y N 485 
TRP CE3 CZ3  doub Y N 486 
TRP CE3 HE3  sing N N 487 
TRP CZ2 CH2  doub Y N 488 
TRP CZ2 HZ2  sing N N 489 
TRP CZ3 CH2  sing Y N 490 
TRP CZ3 HZ3  sing N N 491 
TRP CH2 HH2  sing N N 492 
TRP OXT HXT  sing N N 493 
TYR N   CA   sing N N 494 
TYR N   H    sing N N 495 
TYR N   H2   sing N N 496 
TYR CA  C    sing N N 497 
TYR CA  CB   sing N N 498 
TYR CA  HA   sing N N 499 
TYR C   O    doub N N 500 
TYR C   OXT  sing N N 501 
TYR CB  CG   sing N N 502 
TYR CB  HB2  sing N N 503 
TYR CB  HB3  sing N N 504 
TYR CG  CD1  doub Y N 505 
TYR CG  CD2  sing Y N 506 
TYR CD1 CE1  sing Y N 507 
TYR CD1 HD1  sing N N 508 
TYR CD2 CE2  doub Y N 509 
TYR CD2 HD2  sing N N 510 
TYR CE1 CZ   doub Y N 511 
TYR CE1 HE1  sing N N 512 
TYR CE2 CZ   sing Y N 513 
TYR CE2 HE2  sing N N 514 
TYR CZ  OH   sing N N 515 
TYR OH  HH   sing N N 516 
TYR OXT HXT  sing N N 517 
VAL N   CA   sing N N 518 
VAL N   H    sing N N 519 
VAL N   H2   sing N N 520 
VAL CA  C    sing N N 521 
VAL CA  CB   sing N N 522 
VAL CA  HA   sing N N 523 
VAL C   O    doub N N 524 
VAL C   OXT  sing N N 525 
VAL CB  CG1  sing N N 526 
VAL CB  CG2  sing N N 527 
VAL CB  HB   sing N N 528 
VAL CG1 HG11 sing N N 529 
VAL CG1 HG12 sing N N 530 
VAL CG1 HG13 sing N N 531 
VAL CG2 HG21 sing N N 532 
VAL CG2 HG22 sing N N 533 
VAL CG2 HG23 sing N N 534 
VAL OXT HXT  sing N N 535 
# 
_pdbx_audit_support.funding_organization   'Leukemia & Lymphoma Society' 
_pdbx_audit_support.country                'United States' 
_pdbx_audit_support.grant_number           6649-23 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   4GPQ 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    8VA5 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.020384 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.012495 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.008011 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.pdbx_scat_Z 
_atom_type.pdbx_N_electrons 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
C 6  6  2.3103  20.8439 1.0201 10.2075 1.5888 0.5687  0.8651 51.6512 0.2156   
F 9  9  3.5395  10.2825 2.6414 4.2944  1.5171 0.2615  1.0244 26.1476 0.2776   
H 1  1  0.4930  10.5109 0.3229 26.1257 0.1402 3.1424  0.0408 57.7997 0.0030   
N 7  7  12.2220 0.0057  3.1346 9.8933  2.0141 28.9975 1.1672 0.5826  -11.5379 
O 8  8  3.0487  13.2771 2.2870 5.7011  1.5464 0.3239  0.8671 32.9089 0.2508   
S 16 16 6.9054  1.4679  5.2035 22.2151 1.4379 0.2536  1.5863 56.1720 0.8669   
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
_atom_site.calc_flag 
ATOM   1    C CA   . GLY A 1 7   ? -7.141  18.095  1.150   1.000 37.823 0 2    GLY A CA   1 ? 
ATOM   2    C C    . GLY A 1 7   ? -8.556  17.718  0.713   1.000 32.136 0 2    GLY A C    1 ? 
ATOM   3    O O    . GLY A 1 7   ? -8.972  18.034  -0.401  1.000 33.884 0 2    GLY A O    1 ? 
ATOM   4    H HA2  . GLY A 1 7   ? -6.899  18.972  0.768   1.000 36.159 0 2    GLY A HA2  1 c 
ATOM   5    H HA3  . GLY A 1 7   ? -7.198  18.750  1.898   0.000 0.500  0 2    GLY A HA3  1 c 
ATOM   6    N N    . LEU A 1 8   ? -9.280  16.995  1.579   1.000 25.298 0 3    LEU A N    1 ? 
ATOM   7    C CA   . LEU A 1 8   ? -10.703 16.758  1.383   1.000 21.312 0 3    LEU A CA   1 ? 
ATOM   8    C C    . LEU A 1 8   ? -11.415 18.094  1.392   1.000 20.697 0 3    LEU A C    1 ? 
ATOM   9    O O    . LEU A 1 8   ? -11.112 18.927  2.248   1.000 21.192 0 3    LEU A O    1 ? 
ATOM   10   C CB   . LEU A 1 8   ? -11.359 15.924  2.478   1.000 21.001 0 3    LEU A CB   1 ? 
ATOM   11   C CG   . LEU A 1 8   ? -11.069 14.429  2.483   1.000 20.626 0 3    LEU A CG   1 ? 
ATOM   12   C CD1  . LEU A 1 8   ? -11.503 13.901  3.843   1.000 21.688 0 3    LEU A CD1  1 ? 
ATOM   13   C CD2  . LEU A 1 8   ? -11.828 13.770  1.352   1.000 18.383 0 3    LEU A CD2  1 ? 
ATOM   14   H H    . LEU A 1 8   ? -8.872  16.639  2.315   1.000 25.807 0 3    LEU A H    1 c 
ATOM   15   H HA   . LEU A 1 8   ? -10.835 16.320  0.504   1.000 21.849 0 3    LEU A HA   1 c 
ATOM   16   H HB2  . LEU A 1 8   ? -11.081 16.295  3.347   1.000 20.986 0 3    LEU A HB2  1 c 
ATOM   17   H HB3  . LEU A 1 8   ? -12.334 16.048  2.413   1.000 20.956 0 3    LEU A HB3  1 c 
ATOM   18   H HG   . LEU A 1 8   ? -10.095 14.284  2.362   1.000 20.446 0 3    LEU A HG   1 c 
ATOM   19   H HD11 . LEU A 1 8   ? -10.957 14.305  4.539   1.000 21.366 0 3    LEU A HD11 1 c 
ATOM   20   H HD12 . LEU A 1 8   ? -11.393 12.936  3.867   1.000 21.368 0 3    LEU A HD12 1 c 
ATOM   21   H HD13 . LEU A 1 8   ? -12.437 14.124  3.996   1.000 21.367 0 3    LEU A HD13 1 c 
ATOM   22   H HD21 . LEU A 1 8   ? -11.533 14.139  0.503   1.000 19.038 0 3    LEU A HD21 1 c 
ATOM   23   H HD22 . LEU A 1 8   ? -12.781 13.933  1.461   1.000 19.026 0 3    LEU A HD22 1 c 
ATOM   24   H HD23 . LEU A 1 8   ? -11.662 12.813  1.363   1.000 18.964 0 3    LEU A HD23 1 c 
ATOM   25   N N    . LYS A 1 9   ? -12.440 18.205  0.562   1.000 19.692 0 4    LYS A N    1 ? 
ATOM   26   C CA   . LYS A 1 9   ? -13.240 19.402  0.468   1.000 22.186 0 4    LYS A CA   1 ? 
ATOM   27   C C    . LYS A 1 9   ? -14.447 19.335  1.397   1.000 18.889 0 4    LYS A C    1 ? 
ATOM   28   O O    . LYS A 1 9   ? -14.923 18.266  1.709   1.000 16.110 0 4    LYS A O    1 ? 
ATOM   29   C CB   . LYS A 1 9   ? -13.766 19.617  -0.962  1.000 23.810 0 4    LYS A CB   1 ? 
ATOM   30   C CG   . LYS A 1 9   ? -12.721 19.697  -2.074  1.000 30.663 0 4    LYS A CG   1 ? 
ATOM   31   C CD   . LYS A 1 9   ? -11.878 20.958  -2.058  1.000 38.281 0 4    LYS A CD   1 ? 
ATOM   32   C CE   . LYS A 1 9   ? -11.233 21.170  -3.387  1.000 46.308 0 4    LYS A CE   1 ? 
ATOM   33   N NZ   . LYS A 1 9   ? -10.562 19.960  -3.876  1.000 50.880 0 4    LYS A NZ   1 ? 
ATOM   34   H H    . LYS A 1 9   ? -12.655 17.496  0.026   1.000 20.512 0 4    LYS A H    1 c 
ATOM   35   H HA   . LYS A 1 9   ? -12.681 20.179  0.725   1.000 21.295 0 4    LYS A HA   1 c 
ATOM   36   H HB2  . LYS A 1 9   ? -14.381 18.883  -1.176  1.000 24.794 0 4    LYS A HB2  1 c 
ATOM   37   H HB3  . LYS A 1 9   ? -14.288 20.448  -0.975  1.000 24.794 0 4    LYS A HB3  1 c 
ATOM   38   H HG2  . LYS A 1 9   ? -12.129 18.918  -1.999  1.000 30.574 0 4    LYS A HG2  1 c 
ATOM   39   H HG3  . LYS A 1 9   ? -13.184 19.636  -2.938  1.000 30.546 0 4    LYS A HG3  1 c 
ATOM   40   H HD2  . LYS A 1 9   ? -12.446 21.730  -1.845  1.000 38.045 0 4    LYS A HD2  1 c 
ATOM   41   H HD3  . LYS A 1 9   ? -11.183 20.879  -1.368  1.000 38.045 0 4    LYS A HD3  1 c 
ATOM   42   H HE2  . LYS A 1 9   ? -11.909 21.439  -4.034  1.000 45.318 0 4    LYS A HE2  1 c 
ATOM   43   H HE3  . LYS A 1 9   ? -10.578 21.888  -3.317  1.000 45.319 0 4    LYS A HE3  1 c 
ATOM   44   H HZ1  . LYS A 1 9   ? -11.164 19.405  -4.264  1.000 49.215 0 4    LYS A HZ1  1 c 
ATOM   45   H HZ2  . LYS A 1 9   ? -10.153 19.530  -3.191  1.000 49.043 0 4    LYS A HZ2  1 c 
ATOM   46   H HZ3  . LYS A 1 9   ? -9.938  20.190  -4.491  1.000 49.313 0 4    LYS A HZ3  1 c 
ATOM   47   N N    . ALA A 1 10  ? -14.985 20.496  1.833   1.000 19.184 0 5    ALA A N    1 ? 
ATOM   48   C CA   . ALA A 1 10  ? -16.076 20.526  2.781   1.000 18.122 0 5    ALA A CA   1 ? 
ATOM   49   C C    . ALA A 1 10  ? -17.224 19.632  2.340   1.000 17.109 0 5    ALA A C    1 ? 
ATOM   50   O O    . ALA A 1 10  ? -17.797 18.908  3.147   1.000 17.082 0 5    ALA A O    1 ? 
ATOM   51   C CB   . ALA A 1 10  ? -16.543 21.972  2.978   1.000 19.524 0 5    ALA A CB   1 ? 
ATOM   52   H H    . ALA A 1 10  ? -14.651 21.287  1.520   1.000 18.910 0 5    ALA A H    1 c 
ATOM   53   H HA   . ALA A 1 10  ? -15.735 20.179  3.651   1.000 18.377 0 5    ALA A HA   1 c 
ATOM   54   H HB1  . ALA A 1 10  ? -15.808 22.510  3.317   1.000 19.102 0 5    ALA A HB1  1 c 
ATOM   55   H HB2  . ALA A 1 10  ? -16.844 22.338  2.129   1.000 19.102 0 5    ALA A HB2  1 c 
ATOM   56   H HB3  . ALA A 1 10  ? -17.277 21.995  3.615   1.000 19.102 0 5    ALA A HB3  1 c 
ATOM   57   N N    . ALA A 1 11  ? -17.576 19.672  1.045   1.000 17.905 0 6    ALA A N    1 ? 
ATOM   58   C CA   . ALA A 1 11  ? -18.729 18.929  0.547   1.000 18.362 0 6    ALA A CA   1 ? 
ATOM   59   C C    . ALA A 1 11  ? -18.515 17.421  0.611   1.000 19.719 0 6    ALA A C    1 ? 
ATOM   60   O O    . ALA A 1 11  ? -19.477 16.687  0.733   1.000 21.437 0 6    ALA A O    1 ? 
ATOM   61   C CB   . ALA A 1 11  ? -19.086 19.300  -0.884  1.000 20.157 0 6    ALA A CB   1 ? 
ATOM   62   H H    . ALA A 1 11  ? -17.091 20.178  0.460   1.000 17.843 0 6    ALA A H    1 c 
ATOM   63   H HA   . ALA A 1 11  ? -19.505 19.150  1.132   1.000 18.813 0 6    ALA A HA   1 c 
ATOM   64   H HB1  . ALA A 1 11  ? -19.310 20.244  -0.930  1.000 19.688 0 6    ALA A HB1  1 c 
ATOM   65   H HB2  . ALA A 1 11  ? -18.329 19.122  -1.467  1.000 19.629 0 6    ALA A HB2  1 c 
ATOM   66   H HB3  . ALA A 1 11  ? -19.848 18.774  -1.178  1.000 19.629 0 6    ALA A HB3  1 c 
ATOM   67   N N    . GLN A 1 12  ? -17.260 16.964  0.634   1.000 16.347 0 7    GLN A N    1 ? 
ATOM   68   C CA   . GLN A 1 12  ? -16.995 15.535  0.759   1.000 16.727 0 7    GLN A CA   1 ? 
ATOM   69   C C    . GLN A 1 12  ? -17.191 15.035  2.174   1.000 17.448 0 7    GLN A C    1 ? 
ATOM   70   O O    . GLN A 1 12  ? -17.219 13.845  2.397   1.000 18.651 0 7    GLN A O    1 ? 
ATOM   71   C CB   . GLN A 1 12  ? -15.575 15.231  0.323   1.000 16.213 0 7    GLN A CB   1 ? 
ATOM   72   C CG   . GLN A 1 12  ? -15.273 15.627  -1.120  1.000 16.206 0 7    GLN A CG   1 ? 
ATOM   73   C CD   . GLN A 1 12  ? -13.861 15.266  -1.486  1.000 18.950 0 7    GLN A CD   1 ? 
ATOM   74   O OE1  . GLN A 1 12  ? -12.916 16.048  -1.294  1.000 18.804 0 7    GLN A OE1  1 ? 
ATOM   75   N NE2  . GLN A 1 12  ? -13.702 14.028  -1.977  1.000 16.406 0 7    GLN A NE2  1 ? 
ATOM   76   H H    . GLN A 1 12  ? -16.557 17.543  0.563   1.000 17.191 0 7    GLN A H    1 c 
ATOM   77   H HA   . GLN A 1 12  ? -17.618 15.048  0.161   1.000 16.719 0 7    GLN A HA   1 c 
ATOM   78   H HB2  . GLN A 1 12  ? -14.956 15.703  0.918   1.000 16.336 0 7    GLN A HB2  1 c 
ATOM   79   H HB3  . GLN A 1 12  ? -15.413 14.270  0.429   1.000 16.346 0 7    GLN A HB3  1 c 
ATOM   80   H HG2  . GLN A 1 12  ? -15.896 15.171  -1.725  1.000 16.800 0 7    GLN A HG2  1 c 
ATOM   81   H HG3  . GLN A 1 12  ? -15.396 16.594  -1.229  1.000 16.805 0 7    GLN A HG3  1 c 
ATOM   82   H HE21 . GLN A 1 12  ? -14.391 13.592  -2.326  1.000 17.078 0 7    GLN A HE21 1 c 
ATOM   83   H HE22 . GLN A 1 12  ? -12.901 13.646  -1.949  1.000 16.980 0 7    GLN A HE22 1 c 
ATOM   84   N N    . LYS A 1 13  ? -17.317 15.949  3.152   1.000 16.903 0 8    LYS A N    1 ? 
ATOM   85   C CA   . LYS A 1 13  ? -17.230 15.590  4.554   1.000 16.055 0 8    LYS A CA   1 ? 
ATOM   86   C C    . LYS A 1 13  ? -18.607 15.501  5.220   1.000 15.956 0 8    LYS A C    1 ? 
ATOM   87   O O    . LYS A 1 13  ? -18.704 14.940  6.312   1.000 16.614 0 8    LYS A O    1 ? 
ATOM   88   C CB   . LYS A 1 13  ? -16.372 16.608  5.313   1.000 15.863 0 8    LYS A CB   1 ? 
ATOM   89   C CG   . LYS A 1 13  ? -14.961 16.686  4.822   1.000 17.172 0 8    LYS A CG   1 ? 
ATOM   90   C CD   . LYS A 1 13  ? -14.248 17.749  5.634   1.000 19.843 0 8    LYS A CD   1 ? 
ATOM   91   C CE   . LYS A 1 13  ? -12.859 17.951  5.251   1.000 21.436 0 8    LYS A CE   1 ? 
ATOM   92   N NZ   . LYS A 1 13  ? -12.243 18.916  6.177   1.000 23.661 0 8    LYS A NZ   1 ? 
ATOM   93   H H    . LYS A 1 13  ? -17.455 16.826  2.935   1.000 16.853 0 8    LYS A H    1 c 
ATOM   94   H HA   . LYS A 1 13  ? -16.791 14.704  4.624   1.000 16.185 0 8    LYS A HA   1 c 
ATOM   95   H HB2  . LYS A 1 13  ? -16.783 17.496  5.230   1.000 16.252 0 8    LYS A HB2  1 c 
ATOM   96   H HB3  . LYS A 1 13  ? -16.360 16.370  6.265   1.000 16.247 0 8    LYS A HB3  1 c 
ATOM   97   H HG2  . LYS A 1 13  ? -14.521 15.816  4.944   1.000 17.418 0 8    LYS A HG2  1 c 
ATOM   98   H HG3  . LYS A 1 13  ? -14.954 16.926  3.871   1.000 17.410 0 8    LYS A HG3  1 c 
ATOM   99   H HD2  . LYS A 1 13  ? -14.730 18.599  5.535   1.000 19.516 0 8    LYS A HD2  1 c 
ATOM   100  H HD3  . LYS A 1 13  ? -14.283 17.497  6.582   1.000 19.556 0 8    LYS A HD3  1 c 
ATOM   101  H HE2  . LYS A 1 13  ? -12.374 17.107  5.293   1.000 21.541 0 8    LYS A HE2  1 c 
ATOM   102  H HE3  . LYS A 1 13  ? -12.809 18.297  4.342   1.000 21.541 0 8    LYS A HE3  1 c 
ATOM   103  H HZ1  . LYS A 1 13  ? -12.293 18.607  7.027   1.000 22.902 0 8    LYS A HZ1  1 c 
ATOM   104  H HZ2  . LYS A 1 13  ? -12.673 19.711  6.122   1.000 22.922 0 8    LYS A HZ2  1 c 
ATOM   105  H HZ3  . LYS A 1 13  ? -11.373 19.036  5.956   1.000 22.937 0 8    LYS A HZ3  1 c 
ATOM   106  N N    . THR A 1 14  ? -19.660 16.017  4.567   1.000 17.323 0 9    THR A N    1 ? 
ATOM   107  C CA   . THR A 1 14  ? -20.941 16.252  5.231   1.000 19.982 0 9    THR A CA   1 ? 
ATOM   108  C C    . THR A 1 14  ? -21.701 14.976  5.600   1.000 18.961 0 9    THR A C    1 ? 
ATOM   109  O O    . THR A 1 14  ? -22.532 15.003  6.500   1.000 21.647 0 9    THR A O    1 ? 
ATOM   110  C CB   . THR A 1 14  ? -21.822 17.155  4.369   1.000 21.556 0 9    THR A CB   1 ? 
ATOM   111  O OG1  . THR A 1 14  ? -22.144 16.414  3.193   1.000 25.648 0 9    THR A OG1  1 ? 
ATOM   112  C CG2  . THR A 1 14  ? -21.155 18.452  3.957   1.000 24.257 0 9    THR A CG2  1 ? 
ATOM   113  H H    . THR A 1 14  ? -19.585 16.209  3.677   1.000 17.619 0 9    THR A H    1 c 
ATOM   114  H HA   . THR A 1 14  ? -20.751 16.735  6.064   1.000 19.500 0 9    THR A HA   1 c 
ATOM   115  H HB   . THR A 1 14  ? -22.654 17.364  4.859   1.000 22.480 0 9    THR A HB   1 c 
ATOM   116  H HG1  . THR A 1 14  ? -21.418 16.205  2.773   0.000 25.680 0 9    THR A HG1  1 c 
ATOM   117  H HG21 . THR A 1 14  ? -21.808 19.032  3.530   1.000 23.393 0 9    THR A HG21 1 c 
ATOM   118  H HG22 . THR A 1 14  ? -20.433 18.265  3.333   1.000 23.296 0 9    THR A HG22 1 c 
ATOM   119  H HG23 . THR A 1 14  ? -20.795 18.897  4.743   1.000 23.393 0 9    THR A HG23 1 c 
ATOM   120  N N    . LEU A 1 15  ? -21.432 13.831  4.966   1.000 19.733 0 10   LEU A N    1 ? 
ATOM   121  C CA   . LEU A 1 15  ? -22.171 12.618  5.294   1.000 19.709 0 10   LEU A CA   1 ? 
ATOM   122  C C    . LEU A 1 15  ? -21.599 11.876  6.496   1.000 19.799 0 10   LEU A C    1 ? 
ATOM   123  O O    . LEU A 1 15  ? -22.247 10.980  7.073   1.000 21.675 0 10   LEU A O    1 ? 
ATOM   124  C CB   . LEU A 1 15  ? -22.193 11.708  4.073   1.000 19.273 0 10   LEU A CB   1 ? 
ATOM   125  C CG   . LEU A 1 15  ? -23.096 12.166  2.928   1.000 21.522 0 10   LEU A CG   1 ? 
ATOM   126  C CD1  . LEU A 1 15  ? -22.816 11.302  1.710   1.000 20.409 0 10   LEU A CD1  1 ? 
ATOM   127  C CD2  . LEU A 1 15  ? -24.594 12.094  3.186   1.000 26.325 0 10   LEU A CD2  1 ? 
ATOM   128  H H    . LEU A 1 15  ? -20.786 13.802  4.320   1.000 19.505 0 10   LEU A H    1 c 
ATOM   129  H HA   . LEU A 1 15  ? -23.102 12.876  5.511   1.000 19.712 0 10   LEU A HA   1 c 
ATOM   130  H HB2  . LEU A 1 15  ? -21.274 11.618  3.734   1.000 19.866 0 10   LEU A HB2  1 c 
ATOM   131  H HB3  . LEU A 1 15  ? -22.488 10.814  4.361   1.000 19.917 0 10   LEU A HB3  1 c 
ATOM   132  H HG   . LEU A 1 15  ? -22.864 13.104  2.704   1.000 21.680 0 10   LEU A HG   1 c 
ATOM   133  H HD11 . LEU A 1 15  ? -21.882 11.392  1.456   1.000 20.738 0 10   LEU A HD11 1 c 
ATOM   134  H HD12 . LEU A 1 15  ? -23.379 11.588  0.972   1.000 20.784 0 10   LEU A HD12 1 c 
ATOM   135  H HD13 . LEU A 1 15  ? -23.005 10.372  1.921   1.000 20.743 0 10   LEU A HD13 1 c 
ATOM   136  H HD21 . LEU A 1 15  ? -24.819 12.647  3.953   1.000 24.762 0 10   LEU A HD21 1 c 
ATOM   137  H HD22 . LEU A 1 15  ? -24.849 11.174  3.365   1.000 24.815 0 10   LEU A HD22 1 c 
ATOM   138  H HD23 . LEU A 1 15  ? -25.074 12.416  2.405   1.000 24.770 0 10   LEU A HD23 1 c 
ATOM   139  N N    . PHE A 1 16  ? -20.366 12.203  6.888   1.000 16.187 0 11   PHE A N    1 ? 
ATOM   140  C CA   . PHE A 1 16  ? -19.760 11.532  8.012   1.000 16.750 0 11   PHE A CA   1 ? 
ATOM   141  C C    . PHE A 1 16  ? -20.496 11.935  9.288   1.000 16.888 0 11   PHE A C    1 ? 
ATOM   142  O O    . PHE A 1 16  ? -20.928 13.087  9.424   1.000 18.181 0 11   PHE A O    1 ? 
ATOM   143  C CB   . PHE A 1 16  ? -18.270 11.865  8.082   1.000 14.371 0 11   PHE A CB   1 ? 
ATOM   144  C CG   . PHE A 1 16  ? -17.485 11.175  6.975   1.000 13.638 0 11   PHE A CG   1 ? 
ATOM   145  C CD1  . PHE A 1 16  ? -17.309 11.728  5.713   1.000 13.973 0 11   PHE A CD1  1 ? 
ATOM   146  C CD2  . PHE A 1 16  ? -16.943 9.917   7.214   1.000 13.338 0 11   PHE A CD2  1 ? 
ATOM   147  C CE1  . PHE A 1 16  ? -16.588 11.039  4.733   1.000 14.355 0 11   PHE A CE1  1 ? 
ATOM   148  C CE2  . PHE A 1 16  ? -16.250 9.248   6.241   1.000 13.308 0 11   PHE A CE2  1 ? 
ATOM   149  C CZ   . PHE A 1 16  ? -16.082 9.796   4.989   1.000 13.240 0 11   PHE A CZ   1 ? 
ATOM   150  H H    . PHE A 1 16  ? -19.895 12.849  6.444   1.000 17.119 0 11   PHE A H    1 c 
ATOM   151  H HA   . PHE A 1 16  ? -19.857 10.555  7.879   1.000 16.203 0 11   PHE A HA   1 c 
ATOM   152  H HB2  . PHE A 1 16  ? -18.156 12.839  8.004   1.000 14.727 0 11   PHE A HB2  1 c 
ATOM   153  H HB3  . PHE A 1 16  ? -17.921 11.577  8.954   1.000 14.743 0 11   PHE A HB3  1 c 
ATOM   154  H HD1  . PHE A 1 16  ? -17.668 12.580  5.522   1.000 13.985 0 11   PHE A HD1  1 c 
ATOM   155  H HD2  . PHE A 1 16  ? -17.061 9.516   8.059   1.000 13.408 0 11   PHE A HD2  1 c 
ATOM   156  H HE1  . PHE A 1 16  ? -16.475 11.425  3.879   1.000 13.985 0 11   PHE A HE1  1 c 
ATOM   157  H HE2  . PHE A 1 16  ? -15.891 8.395   6.429   1.000 13.299 0 11   PHE A HE2  1 c 
ATOM   158  H HZ   . PHE A 1 16  ? -15.587 9.337   4.329   1.000 13.515 0 11   PHE A HZ   1 c 
ATOM   159  N N    . PRO A 1 17  ? -20.576 11.060  10.297  1.000 14.829 0 12   PRO A N    1 ? 
ATOM   160  C CA   . PRO A 1 17  ? -20.017 9.701   10.267  1.000 14.650 0 12   PRO A CA   1 ? 
ATOM   161  C C    . PRO A 1 17  ? -20.855 8.706   9.487   1.000 14.572 0 12   PRO A C    1 ? 
ATOM   162  O O    . PRO A 1 17  ? -22.085 8.793   9.441   1.000 14.937 0 12   PRO A O    1 ? 
ATOM   163  C CB   . PRO A 1 17  ? -19.992 9.334   11.753  1.000 14.999 0 12   PRO A CB   1 ? 
ATOM   164  C CG   . PRO A 1 17  ? -21.217 10.036  12.290  1.000 16.721 0 12   PRO A CG   1 ? 
ATOM   165  C CD   . PRO A 1 17  ? -21.173 11.370  11.620  1.000 15.362 0 12   PRO A CD   1 ? 
ATOM   166  H HA   . PRO A 1 17  ? -19.094 9.728   9.913   1.000 14.724 0 12   PRO A HA   1 c 
ATOM   167  H HB2  . PRO A 1 17  ? -20.056 8.358   11.881  1.000 15.288 0 12   PRO A HB2  1 c 
ATOM   168  H HB3  . PRO A 1 17  ? -19.172 9.668   12.187  1.000 15.291 0 12   PRO A HB3  1 c 
ATOM   169  H HG2  . PRO A 1 17  ? -22.035 9.551   12.053  1.000 15.997 0 12   PRO A HG2  1 c 
ATOM   170  H HG3  . PRO A 1 17  ? -21.171 10.131  13.265  1.000 16.002 0 12   PRO A HG3  1 c 
ATOM   171  H HD2  . PRO A 1 17  ? -22.076 11.746  11.523  1.000 15.535 0 12   PRO A HD2  1 c 
ATOM   172  H HD3  . PRO A 1 17  ? -20.612 12.000  12.124  1.000 15.535 0 12   PRO A HD3  1 c 
ATOM   173  N N    . LEU A 1 18  ? -20.197 7.702   8.906   1.000 11.694 0 13   LEU A N    1 ? 
ATOM   174  C CA   . LEU A 1 18  ? -20.916 6.667   8.189   1.000 11.863 0 13   LEU A CA   1 ? 
ATOM   175  C C    . LEU A 1 18  ? -21.248 5.553   9.163   1.000 12.378 0 13   LEU A C    1 ? 
ATOM   176  O O    . LEU A 1 18  ? -20.360 4.905   9.745   1.000 13.198 0 13   LEU A O    1 ? 
ATOM   177  C CB   . LEU A 1 18  ? -20.080 6.097   7.047   1.000 12.424 0 13   LEU A CB   1 ? 
ATOM   178  C CG   . LEU A 1 18  ? -19.365 7.116   6.167   1.000 12.984 0 13   LEU A CG   1 ? 
ATOM   179  C CD1  . LEU A 1 18  ? -18.504 6.426   5.104   1.000 12.613 0 13   LEU A CD1  1 ? 
ATOM   180  C CD2  . LEU A 1 18  ? -20.385 8.000   5.529   1.000 13.528 0 13   LEU A CD2  1 ? 
ATOM   181  H H    . LEU A 1 18  ? -19.286 7.654   8.966   1.000 12.404 0 13   LEU A H    1 c 
ATOM   182  H HA   . LEU A 1 18  ? -21.754 7.050   7.824   1.000 12.063 0 13   LEU A HA   1 c 
ATOM   183  H HB2  . LEU A 1 18  ? -19.403 5.494   7.431   1.000 12.416 0 13   LEU A HB2  1 c 
ATOM   184  H HB3  . LEU A 1 18  ? -20.670 5.554   6.475   1.000 12.423 0 13   LEU A HB3  1 c 
ATOM   185  H HG   . LEU A 1 18  ? -18.776 7.672   6.738   1.000 12.900 0 13   LEU A HG   1 c 
ATOM   186  H HD11 . LEU A 1 18  ? -17.854 5.847   5.537   1.000 12.720 0 13   LEU A HD11 1 c 
ATOM   187  H HD12 . LEU A 1 18  ? -18.037 7.097   4.578   1.000 12.718 0 13   LEU A HD12 1 c 
ATOM   188  H HD13 . LEU A 1 18  ? -19.071 5.895   4.520   1.000 12.720 0 13   LEU A HD13 1 c 
ATOM   189  H HD21 . LEU A 1 18  ? -20.807 8.554   6.207   1.000 13.342 0 13   LEU A HD21 1 c 
ATOM   190  H HD22 . LEU A 1 18  ? -21.060 7.455   5.091   1.000 13.346 0 13   LEU A HD22 1 c 
ATOM   191  H HD23 . LEU A 1 18  ? -19.953 8.570   4.870   1.000 13.355 0 13   LEU A HD23 1 c 
ATOM   192  N N    . ARG A 1 19  ? -22.562 5.374   9.383   1.000 11.683 0 14   ARG A N    1 ? 
ATOM   193  C CA   . ARG A 1 19  ? -23.016 4.506   10.454  1.000 12.913 0 14   ARG A CA   1 ? 
ATOM   194  C C    . ARG A 1 19  ? -23.588 3.167   9.998   1.000 13.371 0 14   ARG A C    1 ? 
ATOM   195  O O    . ARG A 1 19  ? -24.029 2.345   10.800  1.000 14.892 0 14   ARG A O    1 ? 
ATOM   196  C CB   . ARG A 1 19  ? -24.058 5.177   11.369  1.000 13.247 0 14   ARG A CB   1 ? 
ATOM   197  C CG   . ARG A 1 19  ? -23.576 6.464   12.017  1.000 15.289 0 14   ARG A CG   1 ? 
ATOM   198  C CD   . ARG A 1 19  ? -24.658 7.070   12.935  1.000 17.213 0 14   ARG A CD   1 ? 
ATOM   199  N NE   . ARG A 1 19  ? -24.117 8.191   13.714  1.000 20.881 0 14   ARG A NE   1 ? 
ATOM   200  C CZ   . ARG A 1 19  ? -23.341 8.136   14.806  1.000 22.707 0 14   ARG A CZ   1 ? 
ATOM   201  N NH1  . ARG A 1 19  ? -22.906 7.000   15.338  1.000 24.292 0 14   ARG A NH1  1 ? 
ATOM   202  N NH2  . ARG A 1 19  ? -22.989 9.282   15.379  1.000 27.513 0 14   ARG A NH2  1 ? 
ATOM   203  H H    . ARG A 1 19  ? -23.180 5.799   8.861   1.000 12.127 0 14   ARG A H    1 c 
ATOM   204  H HA   . ARG A 1 19  ? -22.234 4.308   11.029  1.000 12.807 0 14   ARG A HA   1 c 
ATOM   205  H HB2  . ARG A 1 19  ? -24.861 5.372   10.841  1.000 13.614 0 14   ARG A HB2  1 c 
ATOM   206  H HB3  . ARG A 1 19  ? -24.312 4.547   12.076  1.000 13.619 0 14   ARG A HB3  1 c 
ATOM   207  H HG2  . ARG A 1 19  ? -22.770 6.281   12.547  1.000 15.236 0 14   ARG A HG2  1 c 
ATOM   208  H HG3  . ARG A 1 19  ? -23.345 7.115   11.319  1.000 15.184 0 14   ARG A HG3  1 c 
ATOM   209  H HD2  . ARG A 1 19  ? -25.409 7.386   12.391  1.000 17.560 0 14   ARG A HD2  1 c 
ATOM   210  H HD3  . ARG A 1 19  ? -24.992 6.382   13.546  1.000 17.587 0 14   ARG A HD3  1 c 
ATOM   211  H HE   . ARG A 1 19  ? -24.324 8.989   13.433  1.000 20.447 0 14   ARG A HE   1 c 
ATOM   212  H HH11 . ARG A 1 19  ? -22.509 7.006   16.128  1.000 23.792 0 14   ARG A HH11 1 c 
ATOM   213  H HH12 . ARG A 1 19  ? -23.012 6.238   14.903  1.000 23.612 0 14   ARG A HH12 1 c 
ATOM   214  H HH21 . ARG A 1 19  ? -22.439 9.278   16.072  1.000 25.877 0 14   ARG A HH21 1 c 
ATOM   215  H HH22 . ARG A 1 19  ? -23.304 10.048  15.070  1.000 25.825 0 14   ARG A HH22 1 c 
ATOM   216  N N    . SER A 1 20  ? -23.665 2.954   8.671   1.000 12.815 0 15   SER A N    1 ? 
ATOM   217  C CA   . SER A 1 20  ? -24.353 1.809   8.089   1.000 12.092 0 15   SER A CA   1 ? 
ATOM   218  C C    . SER A 1 20  ? -23.882 1.579   6.655   1.000 10.786 0 15   SER A C    1 ? 
ATOM   219  O O    . SER A 1 20  ? -23.275 2.476   6.058   1.000 11.219 0 15   SER A O    1 ? 
ATOM   220  C CB   . SER A 1 20  ? -25.850 2.041   8.039   1.000 12.122 0 15   SER A CB   1 ? 
ATOM   221  O OG   . SER A 1 20  ? -26.165 3.120   7.175   1.000 12.914 0 15   SER A OG   1 ? 
ATOM   222  H H    . SER A 1 20  ? -23.264 3.550   8.106   1.000 12.743 0 15   SER A H    1 c 
ATOM   223  H HA   . SER A 1 20  ? -24.161 1.001   8.629   1.000 11.993 0 15   SER A HA   1 c 
ATOM   224  H HB2  . SER A 1 20  ? -26.291 1.231   7.723   1.000 12.302 0 15   SER A HB2  1 c 
ATOM   225  H HB3  . SER A 1 20  ? -26.177 2.237   8.937   1.000 12.304 0 15   SER A HB3  1 c 
ATOM   226  H HG   . SER A 1 20  ? -27.005 3.222   7.168   0.000 12.910 0 15   SER A HG   1 c 
ATOM   227  N N    . ILE A 1 21  ? -24.211 0.399   6.139   1.000 10.490 0 16   ILE A N    1 ? 
ATOM   228  C CA   . ILE A 1 21  ? -24.043 0.085   4.719   1.000 10.268 0 16   ILE A CA   1 ? 
ATOM   229  C C    . ILE A 1 21  ? -24.665 1.172   3.856   1.000 11.087 0 16   ILE A C    1 ? 
ATOM   230  O O    . ILE A 1 21  ? -24.045 1.666   2.909   1.000 10.371 0 16   ILE A O    1 ? 
ATOM   231  C CB   . ILE A 1 21  ? -24.679 -1.288  4.453   1.000 10.408 0 16   ILE A CB   1 ? 
ATOM   232  C CG1  . ILE A 1 21  ? -23.841 -2.378  5.093   1.000 10.887 0 16   ILE A CG1  1 ? 
ATOM   233  C CG2  . ILE A 1 21  ? -24.877 -1.547  2.965   1.000 12.139 0 16   ILE A CG2  1 ? 
ATOM   234  C CD1  . ILE A 1 21  ? -24.530 -3.714  5.234   1.000 11.902 0 16   ILE A CD1  1 ? 
ATOM   235  H H    . ILE A 1 21  ? -24.564 -0.238  6.691   1.000 10.538 0 16   ILE A H    1 c 
ATOM   236  H HA   . ILE A 1 21  ? -23.088 0.032   4.521   1.000 10.486 0 16   ILE A HA   1 c 
ATOM   237  H HB   . ILE A 1 21  ? -25.559 -1.298  4.880   1.000 10.774 0 16   ILE A HB   1 c 
ATOM   238  H HG12 . ILE A 1 21  ? -23.032 -2.501  4.556   1.000 10.997 0 16   ILE A HG12 1 c 
ATOM   239  H HG13 . ILE A 1 21  ? -23.562 -2.079  5.982   1.000 10.989 0 16   ILE A HG13 1 c 
ATOM   240  H HG21 . ILE A 1 21  ? -25.127 -2.475  2.824   1.000 11.601 0 16   ILE A HG21 1 c 
ATOM   241  H HG22 . ILE A 1 21  ? -24.050 -1.361  2.489   1.000 11.600 0 16   ILE A HG22 1 c 
ATOM   242  H HG23 . ILE A 1 21  ? -25.582 -0.971  2.623   1.000 11.598 0 16   ILE A HG23 1 c 
ATOM   243  H HD11 . ILE A 1 21  ? -25.365 -3.600  5.726   1.000 11.592 0 16   ILE A HD11 1 c 
ATOM   244  H HD12 . ILE A 1 21  ? -23.949 -4.328  5.721   1.000 11.592 0 16   ILE A HD12 1 c 
ATOM   245  H HD13 . ILE A 1 21  ? -24.722 -4.083  4.352   1.000 11.594 0 16   ILE A HD13 1 c 
ATOM   246  N N    . ASP A 1 22  ? -25.895 1.581   4.157   1.000 11.258 0 17   ASP A N    1 ? 
ATOM   247  C CA   . ASP A 1 22  ? -26.570 2.559   3.336   1.000 11.655 0 17   ASP A CA   1 ? 
ATOM   248  C C    . ASP A 1 22  ? -25.854 3.908   3.365   1.000 11.771 0 17   ASP A C    1 ? 
ATOM   249  O O    . ASP A 1 22  ? -25.857 4.671   2.398   1.000 12.350 0 17   ASP A O    1 ? 
ATOM   250  C CB   . ASP A 1 22  ? -28.063 2.661   3.656   1.000 13.088 0 17   ASP A CB   1 ? 
ATOM   251  C CG   . ASP A 1 22  ? -28.889 1.450   3.251   1.000 15.712 0 17   ASP A CG   1 ? 
ATOM   252  O OD1  . ASP A 1 22  ? -28.440 0.626   2.432   1.000 14.961 0 17   ASP A OD1  1 ? 
ATOM   253  O OD2  . ASP A 1 22  ? -30.045 1.319   3.769   1.000 18.685 0 17   ASP A OD2  1 ? 
ATOM   254  H H    . ASP A 1 22  ? -26.325 1.239   4.888   1.000 11.304 0 17   ASP A H    1 c 
ATOM   255  H HA   . ASP A 1 22  ? -26.533 2.235   2.407   1.000 11.876 0 17   ASP A HA   1 c 
ATOM   256  H HB2  . ASP A 1 22  ? -28.169 2.796   4.621   1.000 13.295 0 17   ASP A HB2  1 c 
ATOM   257  H HB3  . ASP A 1 22  ? -28.430 3.447   3.200   1.000 13.288 0 17   ASP A HB3  1 c 
ATOM   258  N N    . ASP A 1 23  ? -25.238 4.275   4.505   1.000 10.610 0 18   ASP A N    1 ? 
ATOM   259  C CA   . ASP A 1 23  ? -24.453 5.511   4.554   1.000 10.935 0 18   ASP A CA   1 ? 
ATOM   260  C C    . ASP A 1 23  ? -23.224 5.433   3.631   1.000 10.603 0 18   ASP A C    1 ? 
ATOM   261  O O    . ASP A 1 23  ? -22.888 6.423   3.013   1.000 11.755 0 18   ASP A O    1 ? 
ATOM   262  C CB   . ASP A 1 23  ? -24.010 5.900   5.961   1.000 11.613 0 18   ASP A CB   1 ? 
ATOM   263  C CG   . ASP A 1 23  ? -25.092 6.383   6.913   1.000 13.955 0 18   ASP A CG   1 ? 
ATOM   264  O OD1  . ASP A 1 23  ? -26.223 6.650   6.445   1.000 16.950 0 18   ASP A OD1  1 ? 
ATOM   265  O OD2  . ASP A 1 23  ? -24.767 6.477   8.120   1.000 14.943 0 18   ASP A OD2  1 ? 
ATOM   266  H H    . ASP A 1 23  ? -25.311 3.761   5.257   1.000 10.957 0 18   ASP A H    1 c 
ATOM   267  H HA   . ASP A 1 23  ? -25.023 6.242   4.232   1.000 11.027 0 18   ASP A HA   1 c 
ATOM   268  H HB2  . ASP A 1 23  ? -23.573 5.126   6.371   1.000 11.951 0 18   ASP A HB2  1 c 
ATOM   269  H HB3  . ASP A 1 23  ? -23.340 6.613   5.888   1.000 11.945 0 18   ASP A HB3  1 c 
ATOM   270  N N    . VAL A 1 24  ? -22.583 4.264   3.583   1.000 10.460 0 19   VAL A N    1 ? 
ATOM   271  C CA   . VAL A 1 24  ? -21.461 4.088   2.647   1.000 9.892  0 19   VAL A CA   1 ? 
ATOM   272  C C    . VAL A 1 24  ? -21.965 4.272   1.198   1.000 10.919 0 19   VAL A C    1 ? 
ATOM   273  O O    . VAL A 1 24  ? -21.349 4.966   0.378   1.000 10.439 0 19   VAL A O    1 ? 
ATOM   274  C CB   . VAL A 1 24  ? -20.727 2.766   2.847   1.000 9.944  0 19   VAL A CB   1 ? 
ATOM   275  C CG1  . VAL A 1 24  ? -19.640 2.588   1.796   1.000 10.236 0 19   VAL A CG1  1 ? 
ATOM   276  C CG2  . VAL A 1 24  ? -20.157 2.675   4.240   1.000 11.064 0 19   VAL A CG2  1 ? 
ATOM   277  H H    . VAL A 1 24  ? -22.834 3.571   4.124   1.000 10.374 0 19   VAL A H    1 c 
ATOM   278  H HA   . VAL A 1 24  ? -20.820 4.804   2.826   1.000 10.201 0 19   VAL A HA   1 c 
ATOM   279  H HB   . VAL A 1 24  ? -21.387 2.042   2.735   1.000 10.190 0 19   VAL A HB   1 c 
ATOM   280  H HG11 . VAL A 1 24  ? -19.115 3.404   1.731   1.000 10.152 0 19   VAL A HG11 1 c 
ATOM   281  H HG12 . VAL A 1 24  ? -20.047 2.396   0.934   1.000 10.155 0 19   VAL A HG12 1 c 
ATOM   282  H HG13 . VAL A 1 24  ? -19.061 1.850   2.050   1.000 10.159 0 19   VAL A HG13 1 c 
ATOM   283  H HG21 . VAL A 1 24  ? -19.633 1.861   4.324   1.000 10.714 0 19   VAL A HG21 1 c 
ATOM   284  H HG22 . VAL A 1 24  ? -20.880 2.661   4.888   1.000 10.716 0 19   VAL A HG22 1 c 
ATOM   285  H HG23 . VAL A 1 24  ? -19.587 3.444   4.408   1.000 10.717 0 19   VAL A HG23 1 c 
ATOM   286  N N    . VAL A 1 25  ? -23.115 3.656   0.885   1.000 10.589 0 20   VAL A N    1 ? 
ATOM   287  C CA   . VAL A 1 25  ? -23.717 3.775   -0.442  1.000 9.825  0 20   VAL A CA   1 ? 
ATOM   288  C C    . VAL A 1 25  ? -23.973 5.254   -0.754  1.000 11.166 0 20   VAL A C    1 ? 
ATOM   289  O O    . VAL A 1 25  ? -23.681 5.709   -1.857  1.000 10.797 0 20   VAL A O    1 ? 
ATOM   290  C CB   . VAL A 1 25  ? -24.954 2.852   -0.624  1.000 10.557 0 20   VAL A CB   1 ? 
ATOM   291  C CG1  . VAL A 1 25  ? -25.585 3.066   -1.998  1.000 12.480 0 20   VAL A CG1  1 ? 
ATOM   292  C CG2  . VAL A 1 25  ? -24.611 1.389   -0.418  1.000 10.914 0 20   VAL A CG2  1 ? 
ATOM   293  H H    . VAL A 1 25  ? -23.539 3.149   1.516   1.000 10.490 0 20   VAL A H    1 c 
ATOM   294  H HA   . VAL A 1 25  ? -23.044 3.466   -1.080  1.000 10.351 0 20   VAL A HA   1 c 
ATOM   295  H HB   . VAL A 1 25  ? -25.616 3.110   0.060   1.000 10.816 0 20   VAL A HB   1 c 
ATOM   296  H HG11 . VAL A 1 25  ? -24.896 3.020   -2.683  1.000 11.876 0 20   VAL A HG11 1 c 
ATOM   297  H HG12 . VAL A 1 25  ? -26.013 3.937   -2.029  1.000 11.873 0 20   VAL A HG12 1 c 
ATOM   298  H HG13 . VAL A 1 25  ? -26.249 2.375   -2.162  1.000 11.866 0 20   VAL A HG13 1 c 
ATOM   299  H HG21 . VAL A 1 25  ? -25.406 0.847   -0.552  1.000 10.812 0 20   VAL A HG21 1 c 
ATOM   300  H HG22 . VAL A 1 25  ? -24.277 1.255   0.483   1.000 10.802 0 20   VAL A HG22 1 c 
ATOM   301  H HG23 . VAL A 1 25  ? -23.928 1.123   -1.057  1.000 10.807 0 20   VAL A HG23 1 c 
ATOM   302  N N    A ARG A 1 26  ? -24.476 6.040   0.212   0.500 11.602 0 21   ARG A N    1 ? 
ATOM   303  N N    B ARG A 1 26  ? -24.494 6.008   0.228   0.500 11.799 0 21   ARG A N    1 ? 
ATOM   304  C CA   A ARG A 1 26  ? -24.722 7.455   -0.036  0.500 11.539 0 21   ARG A CA   1 ? 
ATOM   305  C CA   B ARG A 1 26  ? -24.760 7.423   0.020   0.500 11.976 0 21   ARG A CA   1 ? 
ATOM   306  C C    A ARG A 1 26  ? -23.430 8.194   -0.373  0.500 10.619 0 21   ARG A C    1 ? 
ATOM   307  C C    B ARG A 1 26  ? -23.477 8.176   -0.338  0.500 10.897 0 21   ARG A C    1 ? 
ATOM   308  O O    A ARG A 1 26  ? -23.397 9.104   -1.205  0.500 11.291 0 21   ARG A O    1 ? 
ATOM   309  O O    B ARG A 1 26  ? -23.513 9.068   -1.185  0.500 12.024 0 21   ARG A O    1 ? 
ATOM   310  C CB   A ARG A 1 26  ? -25.347 8.092   1.215   0.500 13.980 0 21   ARG A CB   1 ? 
ATOM   311  C CB   B ARG A 1 26  ? -25.479 8.015   1.251   0.500 14.436 0 21   ARG A CB   1 ? 
ATOM   312  C CG   A ARG A 1 26  ? -26.766 7.600   1.429   0.500 17.179 0 21   ARG A CG   1 ? 
ATOM   313  C CG   B ARG A 1 26  ? -26.999 7.934   1.171   0.500 18.584 0 21   ARG A CG   1 ? 
ATOM   314  C CD   A ARG A 1 26  ? -27.211 7.858   2.849   0.500 20.278 0 21   ARG A CD   1 ? 
ATOM   315  C CD   B ARG A 1 26  ? -27.763 8.823   2.193   0.500 20.340 0 21   ARG A CD   1 ? 
ATOM   316  N NE   A ARG A 1 26  ? -28.652 7.659   3.027   0.500 21.885 0 21   ARG A NE   1 ? 
ATOM   317  N NE   B ARG A 1 26  ? -27.853 8.167   3.506   0.500 23.877 0 21   ARG A NE   1 ? 
ATOM   318  C CZ   A ARG A 1 26  ? -29.199 6.774   3.863   0.500 23.867 0 21   ARG A CZ   1 ? 
ATOM   319  C CZ   B ARG A 1 26  ? -28.433 6.989   3.779   0.500 22.963 0 21   ARG A CZ   1 ? 
ATOM   320  N NH1  A ARG A 1 26  ? -28.443 6.004   4.639   0.500 21.536 0 21   ARG A NH1  1 ? 
ATOM   321  N NH1  B ARG A 1 26  ? -29.295 6.402   2.952   0.500 23.712 0 21   ARG A NH1  1 ? 
ATOM   322  N NH2  A ARG A 1 26  ? -30.515 6.667   3.918   0.500 25.121 0 21   ARG A NH2  1 ? 
ATOM   323  N NH2  B ARG A 1 26  ? -28.183 6.406   4.934   0.500 22.306 0 21   ARG A NH2  1 ? 
ATOM   324  H H    A ARG A 1 26  ? -24.674 5.689   1.033   0.500 11.465 0 21   ARG A H    1 c 
ATOM   325  H H    B ARG A 1 26  ? -24.692 5.633   1.037   0.500 11.663 0 21   ARG A H    1 c 
ATOM   326  H HA   A ARG A 1 26  ? -25.350 7.538   -0.798  0.500 11.774 0 21   ARG A HA   1 c 
ATOM   327  H HA   B ARG A 1 26  ? -25.380 7.502   -0.748  0.500 12.138 0 21   ARG A HA   1 c 
ATOM   328  H HB2  A ARG A 1 26  ? -24.805 7.869   2.001   0.500 14.086 0 21   ARG A HB2  1 c 
ATOM   329  H HB2  B ARG A 1 26  ? -25.178 7.536   2.053   0.500 14.668 0 21   ARG A HB2  1 c 
ATOM   330  H HB3  A ARG A 1 26  ? -25.354 9.068   1.116   0.500 14.047 0 21   ARG A HB3  1 c 
ATOM   331  H HB3  B ARG A 1 26  ? -25.217 8.955   1.349   0.500 14.668 0 21   ARG A HB3  1 c 
ATOM   332  H HG2  A ARG A 1 26  ? -27.371 8.065   0.811   0.500 17.023 0 21   ARG A HG2  1 c 
ATOM   333  H HG2  B ARG A 1 26  ? -27.279 8.187   0.266   0.500 17.960 0 21   ARG A HG2  1 c 
ATOM   334  H HG3  A ARG A 1 26  ? -26.812 6.639   1.244   0.500 17.005 0 21   ARG A HG3  1 c 
ATOM   335  H HG3  B ARG A 1 26  ? -27.271 7.001   1.306   0.500 17.910 0 21   ARG A HG3  1 c 
ATOM   336  H HD2  A ARG A 1 26  ? -26.729 7.257   3.450   0.500 19.784 0 21   ARG A HD2  1 c 
ATOM   337  H HD2  B ARG A 1 26  ? -27.299 9.679   2.290   0.500 20.733 0 21   ARG A HD2  1 c 
ATOM   338  H HD3  A ARG A 1 26  ? -26.981 8.777   3.095   0.500 19.863 0 21   ARG A HD3  1 c 
ATOM   339  H HD3  B ARG A 1 26  ? -28.665 9.003   1.858   0.500 20.814 0 21   ARG A HD3  1 c 
ATOM   340  H HE   A ARG A 1 26  ? -29.193 8.151   2.554   0.500 21.949 0 21   ARG A HE   1 c 
ATOM   341  H HE   B ARG A 1 26  ? -27.494 8.583   4.181   0.500 22.794 0 21   ARG A HE   1 c 
ATOM   342  H HH11 A ARG A 1 26  ? -28.824 5.426   5.189   0.500 22.228 0 21   ARG A HH11 1 c 
ATOM   343  H HH11 B ARG A 1 26  ? -29.652 5.624   3.170   0.500 23.479 0 21   ARG A HH11 1 c 
ATOM   344  H HH12 A ARG A 1 26  ? -27.562 6.072   4.601   0.500 22.228 0 21   ARG A HH12 1 c 
ATOM   345  H HH12 B ARG A 1 26  ? -29.506 6.794   2.188   0.500 23.479 0 21   ARG A HH12 1 c 
ATOM   346  H HH21 A ARG A 1 26  ? -30.886 6.084   4.470   0.500 24.728 0 21   ARG A HH21 1 c 
ATOM   347  H HH21 B ARG A 1 26  ? -28.546 5.621   5.117   0.500 22.492 0 21   ARG A HH21 1 c 
ATOM   348  H HH22 A ARG A 1 26  ? -31.019 7.179   3.403   0.500 24.728 0 21   ARG A HH22 1 c 
ATOM   349  H HH22 B ARG A 1 26  ? -27.653 6.802   5.520   0.500 22.447 0 21   ARG A HH22 1 c 
ATOM   350  N N    . LEU A 1 27  ? -22.358 7.869   0.337   1.000 10.752 0 22   LEU A N    1 ? 
ATOM   351  C CA   . LEU A 1 27  ? -21.079 8.463   0.032   1.000 10.418 0 22   LEU A CA   1 ? 
ATOM   352  C C    . LEU A 1 27  ? -20.642 8.168   -1.401  1.000 10.112 0 22   LEU A C    1 ? 
ATOM   353  O O    . LEU A 1 27  ? -20.184 9.040   -2.115  1.000 10.638 0 22   LEU A O    1 ? 
ATOM   354  C CB   . LEU A 1 27  ? -20.004 8.074   1.054   1.000 11.014 0 22   LEU A CB   1 ? 
ATOM   355  C CG   . LEU A 1 27  ? -18.638 8.666   0.753   1.000 11.920 0 22   LEU A CG   1 ? 
ATOM   356  C CD1  . LEU A 1 27  ? -18.664 10.188  0.844   1.000 15.371 0 22   LEU A CD1  1 ? 
ATOM   357  C CD2  . LEU A 1 27  ? -17.551 8.047   1.614   1.000 12.629 0 22   LEU A CD2  1 ? 
ATOM   358  H H    . LEU A 1 27  ? -22.415 7.269   1.024   1.000 10.715 0 22   LEU A H    1 c 
ATOM   359  H HA   . LEU A 1 27  ? -21.203 9.444   0.090   1.000 10.583 0 22   LEU A HA   1 c 
ATOM   360  H HB2  . LEU A 1 27  ? -20.293 8.383   1.943   1.000 11.074 0 22   LEU A HB2  1 c 
ATOM   361  H HB3  . LEU A 1 27  ? -19.927 7.092   1.068   1.000 11.071 0 22   LEU A HB3  1 c 
ATOM   362  H HG   . LEU A 1 27  ? -18.415 8.439   -0.186  1.000 12.431 0 22   LEU A HG   1 c 
ATOM   363  H HD11 . LEU A 1 27  ? -19.178 10.551  0.102   1.000 14.207 0 22   LEU A HD11 1 c 
ATOM   364  H HD12 . LEU A 1 27  ? -17.756 10.531  0.804   1.000 14.247 0 22   LEU A HD12 1 c 
ATOM   365  H HD13 . LEU A 1 27  ? -19.075 10.457  1.683   1.000 14.247 0 22   LEU A HD13 1 c 
ATOM   366  H HD21 . LEU A 1 27  ? -17.538 7.084   1.480   1.000 12.416 0 22   LEU A HD21 1 c 
ATOM   367  H HD22 . LEU A 1 27  ? -17.729 8.240   2.550   1.000 12.418 0 22   LEU A HD22 1 c 
ATOM   368  H HD23 . LEU A 1 27  ? -16.688 8.419   1.366   1.000 12.416 0 22   LEU A HD23 1 c 
ATOM   369  N N    . PHE A 1 28  ? -20.753 6.900   -1.800  1.000 9.450  0 23   PHE A N    1 ? 
ATOM   370  C CA   . PHE A 1 28  ? -20.410 6.534   -3.175  1.000 9.178  0 23   PHE A CA   1 ? 
ATOM   371  C C    . PHE A 1 28  ? -21.278 7.273   -4.190  1.000 9.196  0 23   PHE A C    1 ? 
ATOM   372  O O    . PHE A 1 28  ? -20.751 7.771   -5.187  1.000 10.607 0 23   PHE A O    1 ? 
ATOM   373  C CB   . PHE A 1 28  ? -20.459 5.007   -3.385  1.000 9.091  0 23   PHE A CB   1 ? 
ATOM   374  C CG   . PHE A 1 28  ? -19.177 4.310   -2.991  1.000 9.330  0 23   PHE A CG   1 ? 
ATOM   375  C CD1  . PHE A 1 28  ? -18.839 4.115   -1.660  1.000 9.388  0 23   PHE A CD1  1 ? 
ATOM   376  C CD2  . PHE A 1 28  ? -18.291 3.872   -3.981  1.000 9.224  0 23   PHE A CD2  1 ? 
ATOM   377  C CE1  . PHE A 1 28  ? -17.660 3.505   -1.310  1.000 9.627  0 23   PHE A CE1  1 ? 
ATOM   378  C CE2  . PHE A 1 28  ? -17.120 3.236   -3.612  1.000 8.841  0 23   PHE A CE2  1 ? 
ATOM   379  C CZ   . PHE A 1 28  ? -16.775 3.115   -2.288  1.000 8.513  0 23   PHE A CZ   1 ? 
ATOM   380  H H    . PHE A 1 28  ? -21.037 6.255   -1.219  1.000 9.549  0 23   PHE A H    1 c 
ATOM   381  H HA   . PHE A 1 28  ? -19.470 6.821   -3.327  1.000 9.237  0 23   PHE A HA   1 c 
ATOM   382  H HB2  . PHE A 1 28  ? -21.200 4.639   -2.855  1.000 9.168  0 23   PHE A HB2  1 c 
ATOM   383  H HB3  . PHE A 1 28  ? -20.643 4.826   -4.334  1.000 9.166  0 23   PHE A HB3  1 c 
ATOM   384  H HD1  . PHE A 1 28  ? -19.420 4.425   -0.986  1.000 9.424  0 23   PHE A HD1  1 c 
ATOM   385  H HD2  . PHE A 1 28  ? -18.502 3.991   -4.893  1.000 9.155  0 23   PHE A HD2  1 c 
ATOM   386  H HE1  . PHE A 1 28  ? -17.439 3.394   -0.399  1.000 9.294  0 23   PHE A HE1  1 c 
ATOM   387  H HE2  . PHE A 1 28  ? -16.513 2.956   -4.279  1.000 8.858  0 23   PHE A HE2  1 c 
ATOM   388  H HZ   . PHE A 1 28  ? -15.984 2.662   -2.051  1.000 8.864  0 23   PHE A HZ   1 c 
ATOM   389  N N    . ALA A 1 29  ? -22.554 7.442   -3.900  1.000 10.534 0 24   ALA A N    1 ? 
ATOM   390  C CA   . ALA A 1 29  ? -23.443 8.141   -4.808  1.000 10.667 0 24   ALA A CA   1 ? 
ATOM   391  C C    . ALA A 1 29  ? -23.037 9.598   -4.907  1.000 11.297 0 24   ALA A C    1 ? 
ATOM   392  O O    . ALA A 1 29  ? -23.041 10.151  -6.000  1.000 13.103 0 24   ALA A O    1 ? 
ATOM   393  C CB   . ALA A 1 29  ? -24.853 8.011   -4.292  1.000 11.096 0 24   ALA A CB   1 ? 
ATOM   394  H H    . ALA A 1 29  ? -22.890 7.110   -3.118  1.000 10.220 0 24   ALA A H    1 c 
ATOM   395  H HA   . ALA A 1 29  ? -23.374 7.725   -5.711  1.000 10.833 0 24   ALA A HA   1 c 
ATOM   396  H HB1  . ALA A 1 29  ? -25.098 7.071   -4.244  1.000 10.968 0 24   ALA A HB1  1 c 
ATOM   397  H HB2  . ALA A 1 29  ? -24.915 8.404   -3.406  1.000 10.972 0 24   ALA A HB2  1 c 
ATOM   398  H HB3  . ALA A 1 29  ? -25.464 8.471   -4.892  1.000 10.968 0 24   ALA A HB3  1 c 
ATOM   399  N N    . ALA A 1 30  ? -22.673 10.215  -3.769  1.000 11.079 0 25   ALA A N    1 ? 
ATOM   400  C CA   . ALA A 1 30  ? -22.298 11.612  -3.782  1.000 11.805 0 25   ALA A CA   1 ? 
ATOM   401  C C    . ALA A 1 30  ? -21.019 11.787  -4.593  1.000 12.250 0 25   ALA A C    1 ? 
ATOM   402  O O    . ALA A 1 30  ? -20.907 12.671  -5.433  1.000 14.230 0 25   ALA A O    1 ? 
ATOM   403  C CB   . ALA A 1 30  ? -22.097 12.127  -2.368  1.000 13.287 0 25   ALA A CB   1 ? 
ATOM   404  H H    . ALA A 1 30  ? -22.666 9.756   -2.978  1.000 11.294 0 25   ALA A H    1 c 
ATOM   405  H HA   . ALA A 1 30  ? -23.026 12.132  -4.222  1.000 11.996 0 25   ALA A HA   1 c 
ATOM   406  H HB1  . ALA A 1 30  ? -22.922 12.029  -1.864  1.000 12.831 0 25   ALA A HB1  1 c 
ATOM   407  H HB2  . ALA A 1 30  ? -21.392 11.618  -1.932  1.000 12.831 0 25   ALA A HB2  1 c 
ATOM   408  H HB3  . ALA A 1 30  ? -21.846 13.065  -2.394  1.000 12.831 0 25   ALA A HB3  1 c 
ATOM   409  N N    . GLU A 1 31  ? -20.013 10.916  -4.357  1.000 11.286 0 26   GLU A N    1 ? 
ATOM   410  C CA   . GLU A 1 31  ? -18.765 11.002  -5.094  1.000 11.244 0 26   GLU A CA   1 ? 
ATOM   411  C C    . GLU A 1 31  ? -18.957 10.744  -6.586  1.000 12.032 0 26   GLU A C    1 ? 
ATOM   412  O O    . GLU A 1 31  ? -18.297 11.394  -7.406  1.000 11.676 0 26   GLU A O    1 ? 
ATOM   413  C CB   . GLU A 1 31  ? -17.666 10.080  -4.538  1.000 10.907 0 26   GLU A CB   1 ? 
ATOM   414  C CG   . GLU A 1 31  ? -17.129 10.558  -3.184  1.000 11.956 0 26   GLU A CG   1 ? 
ATOM   415  C CD   . GLU A 1 31  ? -16.298 11.794  -3.353  1.000 13.254 0 26   GLU A CD   1 ? 
ATOM   416  O OE1  . GLU A 1 31  ? -15.553 11.941  -4.323  1.000 13.523 0 26   GLU A OE1  1 ? 
ATOM   417  O OE2  . GLU A 1 31  ? -16.383 12.645  -2.381  1.000 16.270 0 26   GLU A OE2  1 ? 
ATOM   418  H H    . GLU A 1 31  ? -20.111 10.266  -3.723  1.000 11.494 0 26   GLU A H    1 c 
ATOM   419  H HA   . GLU A 1 31  ? -18.432 11.930  -4.999  1.000 11.359 0 26   GLU A HA   1 c 
ATOM   420  H HB2  . GLU A 1 31  ? -18.034 9.178   -4.434  1.000 11.218 0 26   GLU A HB2  1 c 
ATOM   421  H HB3  . GLU A 1 31  ? -16.933 10.030  -5.186  1.000 11.239 0 26   GLU A HB3  1 c 
ATOM   422  H HG2  . GLU A 1 31  ? -17.879 10.754  -2.582  1.000 12.016 0 26   GLU A HG2  1 c 
ATOM   423  H HG3  . GLU A 1 31  ? -16.579 9.854   -2.780  1.000 11.983 0 26   GLU A HG3  1 c 
ATOM   424  N N    . LEU A 1 32  ? -19.804 9.766   -6.945  1.000 12.407 0 27   LEU A N    1 ? 
ATOM   425  C CA   . LEU A 1 32  ? -20.036 9.476   -8.359  1.000 14.324 0 27   LEU A CA   1 ? 
ATOM   426  C C    . LEU A 1 32  ? -20.750 10.633  -9.060  1.000 16.850 0 27   LEU A C    1 ? 
ATOM   427  O O    . LEU A 1 32  ? -20.693 10.696  -10.303 1.000 19.461 0 27   LEU A O    1 ? 
ATOM   428  C CB   . LEU A 1 32  ? -20.760 8.151   -8.521  1.000 12.763 0 27   LEU A CB   1 ? 
ATOM   429  C CG   . LEU A 1 32  ? -19.915 6.902   -8.210  1.000 12.036 0 27   LEU A CG   1 ? 
ATOM   430  C CD1  . LEU A 1 32  ? -20.771 5.724   -7.925  1.000 11.941 0 27   LEU A CD1  1 ? 
ATOM   431  C CD2  . LEU A 1 32  ? -18.942 6.607   -9.331  1.000 12.475 0 27   LEU A CD2  1 ? 
ATOM   432  H H    . LEU A 1 32  ? -20.237 9.273   -6.308  1.000 12.700 0 27   LEU A H    1 c 
ATOM   433  H HA   . LEU A 1 32  ? -19.146 9.390   -8.786  1.000 14.010 0 27   LEU A HA   1 c 
ATOM   434  H HB2  . LEU A 1 32  ? -21.545 8.154   -7.927  1.000 12.925 0 27   LEU A HB2  1 c 
ATOM   435  H HB3  . LEU A 1 32  ? -21.081 8.086   -9.450  1.000 12.951 0 27   LEU A HB3  1 c 
ATOM   436  H HG   . LEU A 1 32  ? -19.383 7.091   -7.394  1.000 12.221 0 27   LEU A HG   1 c 
ATOM   437  H HD11 . LEU A 1 32  ? -21.330 5.907   -7.151  1.000 11.976 0 27   LEU A HD11 1 c 
ATOM   438  H HD12 . LEU A 1 32  ? -20.210 4.951   -7.742  1.000 11.973 0 27   LEU A HD12 1 c 
ATOM   439  H HD13 . LEU A 1 32  ? -21.335 5.538   -8.694  1.000 11.972 0 27   LEU A HD13 1 c 
ATOM   440  H HD21 . LEU A 1 32  ? -18.313 7.343   -9.419  1.000 12.354 0 27   LEU A HD21 1 c 
ATOM   441  H HD22 . LEU A 1 32  ? -19.430 6.498   -10.164 1.000 12.345 0 27   LEU A HD22 1 c 
ATOM   442  H HD23 . LEU A 1 32  ? -18.456 5.789   -9.132  1.000 12.343 0 27   LEU A HD23 1 c 
ATOM   443  N N    . GLY A 1 33  ? -21.394 11.520  -8.300  1.000 16.836 0 28   GLY A N    1 ? 
ATOM   444  C CA   . GLY A 1 33  ? -22.073 12.694  -8.841  1.000 19.351 0 28   GLY A CA   1 ? 
ATOM   445  C C    . GLY A 1 33  ? -21.145 13.889  -9.019  1.000 22.387 0 28   GLY A C    1 ? 
ATOM   446  O O    . GLY A 1 33  ? -21.560 14.890  -9.611  1.000 21.792 0 28   GLY A O    1 ? 
ATOM   447  H H    . GLY A 1 33  ? -21.434 11.381  -7.399  1.000 17.240 0 28   GLY A H    1 c 
ATOM   448  H HA2  . GLY A 1 33  ? -22.471 12.460  -9.712  1.000 19.328 0 28   GLY A HA2  1 c 
ATOM   449  H HA3  . GLY A 1 33  ? -22.808 12.942  -8.233  1.000 19.339 0 28   GLY A HA3  1 c 
ATOM   450  N N    A ARG A 1 34  ? -19.903 13.775  -8.524  0.500 21.623 0 29   ARG A N    1 ? 
ATOM   451  N N    B ARG A 1 34  ? -19.929 13.830  -8.459  0.500 21.487 0 29   ARG A N    1 ? 
ATOM   452  C CA   A ARG A 1 34  ? -18.916 14.838  -8.613  0.500 23.410 0 29   ARG A CA   1 ? 
ATOM   453  C CA   B ARG A 1 34  ? -18.970 14.916  -8.579  0.500 23.547 0 29   ARG A CA   1 ? 
ATOM   454  C C    A ARG A 1 34  ? -18.142 14.729  -9.919  0.500 26.334 0 29   ARG A C    1 ? 
ATOM   455  C C    B ARG A 1 34  ? -18.209 14.772  -9.897  0.500 26.117 0 29   ARG A C    1 ? 
ATOM   456  O O    A ARG A 1 34  ? -18.103 13.687  -10.577 0.500 26.733 0 29   ARG A O    1 ? 
ATOM   457  O O    B ARG A 1 34  ? -18.288 13.746  -10.566 0.500 27.204 0 29   ARG A O    1 ? 
ATOM   458  C CB   A ARG A 1 34  ? -17.940 14.792  -7.432  0.500 21.279 0 29   ARG A CB   1 ? 
ATOM   459  C CB   B ARG A 1 34  ? -18.071 14.946  -7.335  0.500 21.322 0 29   ARG A CB   1 ? 
ATOM   460  C CG   A ARG A 1 34  ? -18.529 15.236  -6.102  0.500 21.802 0 29   ARG A CG   1 ? 
ATOM   461  C CG   B ARG A 1 34  ? -18.778 15.253  -6.022  0.500 22.449 0 29   ARG A CG   1 ? 
ATOM   462  C CD   A ARG A 1 34  ? -17.554 15.045  -4.939  0.500 20.609 0 29   ARG A CD   1 ? 
ATOM   463  C CD   B ARG A 1 34  ? -17.799 15.598  -4.894  0.500 21.463 0 29   ARG A CD   1 ? 
ATOM   464  N NE   A ARG A 1 34  ? -16.468 16.031  -4.927  0.500 20.610 0 29   ARG A NE   1 ? 
ATOM   465  N NE   B ARG A 1 34  ? -18.006 14.801  -3.682  0.500 21.211 0 29   ARG A NE   1 ? 
ATOM   466  C CZ   A ARG A 1 34  ? -16.595 17.294  -4.545  0.500 21.134 0 29   ARG A CZ   1 ? 
ATOM   467  C CZ   B ARG A 1 34  ? -19.019 14.795  -2.807  0.500 20.049 0 29   ARG A CZ   1 ? 
ATOM   468  N NH1  A ARG A 1 34  ? -17.765 17.758  -4.178  0.500 20.727 0 29   ARG A NH1  1 ? 
ATOM   469  N NH1  B ARG A 1 34  ? -18.999 13.844  -1.876  0.500 15.484 0 29   ARG A NH1  1 ? 
ATOM   470  N NH2  A ARG A 1 34  ? -15.535 18.071  -4.499  0.500 21.711 0 29   ARG A NH2  1 ? 
ATOM   471  N NH2  B ARG A 1 34  ? -20.020 15.679  -2.893  0.500 19.985 0 29   ARG A NH2  1 ? 
ATOM   472  H H    A ARG A 1 34  ? -19.664 13.001  -8.103  0.500 22.017 0 29   ARG A H    1 c 
ATOM   473  H H    B ARG A 1 34  ? -19.691 13.090  -7.979  0.500 21.977 0 29   ARG A H    1 c 
ATOM   474  H HA   A ARG A 1 34  ? -19.390 15.708  -8.597  0.500 23.136 0 29   ARG A HA   1 c 
ATOM   475  H HA   B ARG A 1 34  ? -19.473 15.770  -8.606  0.500 23.137 0 29   ARG A HA   1 c 
ATOM   476  H HB2  A ARG A 1 34  ? -17.606 13.875  -7.336  0.500 21.789 0 29   ARG A HB2  1 c 
ATOM   477  H HB2  B ARG A 1 34  ? -17.629 14.074  -7.254  0.500 22.066 0 29   ARG A HB2  1 c 
ATOM   478  H HB3  A ARG A 1 34  ? -17.171 15.365  -7.640  0.500 21.876 0 29   ARG A HB3  1 c 
ATOM   479  H HB3  B ARG A 1 34  ? -17.371 15.618  -7.477  0.500 22.066 0 29   ARG A HB3  1 c 
ATOM   480  H HG2  A ARG A 1 34  ? -18.776 16.184  -6.160  0.500 21.397 0 29   ARG A HG2  1 c 
ATOM   481  H HG2  B ARG A 1 34  ? -19.391 16.009  -6.155  0.500 21.951 0 29   ARG A HG2  1 c 
ATOM   482  H HG3  A ARG A 1 34  ? -19.345 14.721  -5.923  0.500 21.359 0 29   ARG A HG3  1 c 
ATOM   483  H HG3  B ARG A 1 34  ? -19.311 14.476  -5.753  0.500 21.901 0 29   ARG A HG3  1 c 
ATOM   484  H HD2  A ARG A 1 34  ? -18.051 15.106  -4.098  0.500 20.870 0 29   ARG A HD2  1 c 
ATOM   485  H HD2  B ARG A 1 34  ? -16.885 15.459  -5.216  0.500 21.606 0 29   ARG A HD2  1 c 
ATOM   486  H HD3  A ARG A 1 34  ? -17.170 14.147  -4.993  0.500 20.863 0 29   ARG A HD3  1 c 
ATOM   487  H HD3  B ARG A 1 34  ? -17.895 16.547  -4.673  0.500 21.617 0 29   ARG A HD3  1 c 
ATOM   488  H HE   A ARG A 1 34  ? -15.680 15.771  -5.189  0.500 20.733 0 29   ARG A HE   1 c 
ATOM   489  H HE   B ARG A 1 34  ? -17.368 14.244  -3.489  0.500 20.930 0 29   ARG A HE   1 c 
ATOM   490  H HH11 A ARG A 1 34  ? -17.844 18.601  -3.925  0.500 20.851 0 29   ARG A HH11 1 c 
ATOM   491  H HH11 B ARG A 1 34  ? -19.662 13.786  -1.294  0.500 16.764 0 29   ARG A HH11 1 c 
ATOM   492  H HH12 A ARG A 1 34  ? -18.471 17.225  -4.186  0.500 20.851 0 29   ARG A HH12 1 c 
ATOM   493  H HH12 B ARG A 1 34  ? -18.323 13.276  -1.843  0.500 16.748 0 29   ARG A HH12 1 c 
ATOM   494  H HH21 A ARG A 1 34  ? -15.619 18.913  -4.244  0.500 21.532 0 29   ARG A HH21 1 c 
ATOM   495  H HH21 B ARG A 1 34  ? -20.679 15.654  -2.304  0.500 20.005 0 29   ARG A HH21 1 c 
ATOM   496  H HH22 A ARG A 1 34  ? -14.743 17.747  -4.722  0.500 21.532 0 29   ARG A HH22 1 c 
ATOM   497  H HH22 B ARG A 1 34  ? -20.017 16.284  -3.537  0.500 20.005 0 29   ARG A HH22 1 c 
ATOM   498  N N    . GLU A 1 35  ? -17.461 15.825  -10.272 1.000 27.462 0 30   GLU A N    1 ? 
ATOM   499  C CA   . GLU A 1 35  ? -16.700 15.848  -11.512 1.000 30.655 0 30   GLU A CA   1 ? 
ATOM   500  C C    . GLU A 1 35  ? -15.792 14.621  -11.632 1.000 29.387 0 30   GLU A C    1 ? 
ATOM   501  O O    . GLU A 1 35  ? -15.842 13.954  -12.647 1.000 29.949 0 30   GLU A O    1 ? 
ATOM   502  C CB   . GLU A 1 35  ? -15.932 17.171  -11.621 1.000 32.989 0 30   GLU A CB   1 ? 
ATOM   503  C CG   . GLU A 1 35  ? -15.218 17.373  -12.956 1.000 35.012 0 30   GLU A CG   1 ? 
ATOM   504  H H    . GLU A 1 35  ? -17.447 16.561  -9.730  1.000 27.534 0 30   GLU A H    1 c 
ATOM   505  H HA   . GLU A 1 35  ? -17.348 15.819  -12.262 1.000 30.176 0 30   GLU A HA   1 c 
ATOM   506  H HB2  . GLU A 1 35  ? -16.559 17.912  -11.485 1.000 32.852 0 30   GLU A HB2  1 c 
ATOM   507  H HB3  . GLU A 1 35  ? -15.267 17.209  -10.901 1.000 32.888 0 30   GLU A HB3  1 c 
ATOM   508  H HG2  . GLU A 1 35  ? -14.423 16.799  -12.983 1.000 34.368 0 30   GLU A HG2  1 c 
ATOM   509  H HG3  . GLU A 1 35  ? -15.883 17.341  -13.676 0.000 34.930 0 30   GLU A HG3  1 c 
ATOM   510  N N    . GLU A 1 36  ? -14.996 14.336  -10.582 1.000 24.445 0 31   GLU A N    1 ? 
ATOM   511  C CA   . GLU A 1 36  ? -14.094 13.202  -10.431 1.000 24.800 0 31   GLU A CA   1 ? 
ATOM   512  C C    . GLU A 1 36  ? -14.335 12.562  -9.053  1.000 20.363 0 31   GLU A C    1 ? 
ATOM   513  O O    . GLU A 1 36  ? -13.916 13.137  -8.038  1.000 27.030 0 31   GLU A O    1 ? 
ATOM   514  C CB   . GLU A 1 36  ? -12.668 13.729  -10.277 1.000 28.763 0 31   GLU A CB   1 ? 
ATOM   515  C CG   . GLU A 1 36  ? -12.044 14.320  -11.545 1.000 31.078 0 31   GLU A CG   1 ? 
ATOM   516  C CD   . GLU A 1 36  ? -10.896 13.496  -12.122 1.000 27.061 0 31   GLU A CD   1 ? 
ATOM   517  O OE1  . GLU A 1 36  ? -10.273 12.791  -11.340 1.000 21.408 0 31   GLU A OE1  1 ? 
ATOM   518  O OE2  . GLU A 1 36  ? -10.595 13.598  -13.330 1.000 27.352 0 31   GLU A OE2  1 ? 
ATOM   519  H H    . GLU A 1 36  ? -15.024 14.927  -9.886  1.000 25.628 0 31   GLU A H    1 c 
ATOM   520  H HA   . GLU A 1 36  ? -14.209 12.555  -11.170 1.000 24.438 0 31   GLU A HA   1 c 
ATOM   521  H HB2  . GLU A 1 36  ? -12.668 14.438  -9.600  1.000 28.188 0 31   GLU A HB2  1 c 
ATOM   522  H HB3  . GLU A 1 36  ? -12.101 13.003  -9.945  1.000 27.977 0 31   GLU A HB3  1 c 
ATOM   523  H HG2  . GLU A 1 36  ? -12.739 14.408  -12.232 1.000 29.557 0 31   GLU A HG2  1 c 
ATOM   524  H HG3  . GLU A 1 36  ? -11.710 15.221  -11.346 1.000 29.581 0 31   GLU A HG3  1 c 
ATOM   525  N N    . PRO A 1 37  ? -14.906 11.350  -8.937  1.000 16.507 0 32   PRO A N    1 ? 
ATOM   526  C CA   . PRO A 1 37  ? -14.970 10.692  -7.626  1.000 13.068 0 32   PRO A CA   1 ? 
ATOM   527  C C    . PRO A 1 37  ? -13.579 10.537  -7.042  1.000 11.600 0 32   PRO A C    1 ? 
ATOM   528  O O    . PRO A 1 37  ? -12.608 10.242  -7.745  1.000 11.743 0 32   PRO A O    1 ? 
ATOM   529  C CB   . PRO A 1 37  ? -15.598 9.328   -7.953  1.000 14.291 0 32   PRO A CB   1 ? 
ATOM   530  C CG   . PRO A 1 37  ? -15.145 9.063   -9.348  1.000 17.770 0 32   PRO A CG   1 ? 
ATOM   531  C CD   . PRO A 1 37  ? -15.413 10.436  -9.993  1.000 16.603 0 32   PRO A CD   1 ? 
ATOM   532  H HA   . PRO A 1 37  ? -15.555 11.204  -7.013  1.000 13.564 0 32   PRO A HA   1 c 
ATOM   533  H HB2  . PRO A 1 37  ? -15.273 8.631   -7.336  1.000 14.710 0 32   PRO A HB2  1 c 
ATOM   534  H HB3  . PRO A 1 37  ? -16.582 9.371   -7.903  1.000 14.712 0 32   PRO A HB3  1 c 
ATOM   535  H HG2  . PRO A 1 37  ? -14.194 8.829   -9.381  1.000 16.620 0 32   PRO A HG2  1 c 
ATOM   536  H HG3  . PRO A 1 37  ? -15.675 8.357   -9.772  1.000 16.644 0 32   PRO A HG3  1 c 
ATOM   537  H HD2  . PRO A 1 37  ? -14.912 10.538  -10.832 1.000 16.913 0 32   PRO A HD2  1 c 
ATOM   538  H HD3  . PRO A 1 37  ? -16.372 10.573  -10.158 1.000 16.847 0 32   PRO A HD3  1 c 
ATOM   539  N N    . ASP A 1 38  ? -13.464 10.687  -5.710  1.000 9.731  0 33   ASP A N    1 ? 
ATOM   540  C CA   . ASP A 1 38  ? -12.187 10.676  -5.019  1.000 9.756  0 33   ASP A CA   1 ? 
ATOM   541  C C    . ASP A 1 38  ? -11.801 9.226   -4.715  1.000 8.905  0 33   ASP A C    1 ? 
ATOM   542  O O    . ASP A 1 38  ? -12.311 8.622   -3.759  1.000 8.905  0 33   ASP A O    1 ? 
ATOM   543  C CB   . ASP A 1 38  ? -12.294 11.508  -3.746  1.000 9.941  0 33   ASP A CB   1 ? 
ATOM   544  C CG   . ASP A 1 38  ? -10.986 11.761  -3.057  1.000 11.554 0 33   ASP A CG   1 ? 
ATOM   545  O OD1  . ASP A 1 38  ? -10.121 10.865  -3.090  1.000 10.481 0 33   ASP A OD1  1 ? 
ATOM   546  O OD2  . ASP A 1 38  ? -10.830 12.861  -2.411  1.000 12.164 0 33   ASP A OD2  1 ? 
ATOM   547  H H    . ASP A 1 38  ? -14.224 10.797  -5.214  1.000 10.194 0 33   ASP A H    1 c 
ATOM   548  H HA   . ASP A 1 38  ? -11.507 11.078  -5.605  1.000 9.631  0 33   ASP A HA   1 c 
ATOM   549  H HB2  . ASP A 1 38  ? -12.692 12.375  -3.971  1.000 10.286 0 33   ASP A HB2  1 c 
ATOM   550  H HB3  . ASP A 1 38  ? -12.893 11.058  -3.115  1.000 10.249 0 33   ASP A HB3  1 c 
ATOM   551  N N    . LEU A 1 39  ? -10.880 8.670   -5.518  1.000 8.564  0 34   LEU A N    1 ? 
ATOM   552  C CA   . LEU A 1 39  ? -10.522 7.266   -5.366  1.000 8.900  0 34   LEU A CA   1 ? 
ATOM   553  C C    . LEU A 1 39  ? -9.895  6.974   -4.011  1.000 8.546  0 34   LEU A C    1 ? 
ATOM   554  O O    . LEU A 1 39  ? -10.086 5.869   -3.470  1.000 8.754  0 34   LEU A O    1 ? 
ATOM   555  C CB   . LEU A 1 39  ? -9.556  6.886   -6.486  1.000 8.710  0 34   LEU A CB   1 ? 
ATOM   556  C CG   . LEU A 1 39  ? -10.102 6.968   -7.918  1.000 8.707  0 34   LEU A CG   1 ? 
ATOM   557  C CD1  . LEU A 1 39  ? -8.994  6.537   -8.886  1.000 9.303  0 34   LEU A CD1  1 ? 
ATOM   558  C CD2  . LEU A 1 39  ? -11.338 6.137   -8.136  1.000 9.108  0 34   LEU A CD2  1 ? 
ATOM   559  H H    . LEU A 1 39  ? -10.468 9.172   -6.162  1.000 8.734  0 34   LEU A H    1 c 
ATOM   560  H HA   . LEU A 1 39  ? -11.348 6.725   -5.451  1.000 8.745  0 34   LEU A HA   1 c 
ATOM   561  H HB2  . LEU A 1 39  ? -8.768  7.474   -6.421  1.000 8.752  0 34   LEU A HB2  1 c 
ATOM   562  H HB3  . LEU A 1 39  ? -9.248  5.964   -6.325  1.000 8.751  0 34   LEU A HB3  1 c 
ATOM   563  H HG   . LEU A 1 39  ? -10.328 7.914   -8.110  1.000 8.889  0 34   LEU A HG   1 c 
ATOM   564  H HD11 . LEU A 1 39  ? -8.223  7.118   -8.778  1.000 9.125  0 34   LEU A HD11 1 c 
ATOM   565  H HD12 . LEU A 1 39  ? -9.319  6.598   -9.799  1.000 9.125  0 34   LEU A HD12 1 c 
ATOM   566  H HD13 . LEU A 1 39  ? -8.735  5.619   -8.696  1.000 9.125  0 34   LEU A HD13 1 c 
ATOM   567  H HD21 . LEU A 1 39  ? -12.082 6.525   -7.644  1.000 8.984  0 34   LEU A HD21 1 c 
ATOM   568  H HD22 . LEU A 1 39  ? -11.180 5.231   -7.822  1.000 8.986  0 34   LEU A HD22 1 c 
ATOM   569  H HD23 . LEU A 1 39  ? -11.553 6.118   -9.083  1.000 8.987  0 34   LEU A HD23 1 c 
ATOM   570  N N    . VAL A 1 40  ? -9.077  7.890   -3.505  1.000 8.627  0 35   VAL A N    1 ? 
ATOM   571  C CA   . VAL A 1 40  ? -8.370  7.713   -2.240  1.000 9.024  0 35   VAL A CA   1 ? 
ATOM   572  C C    . VAL A 1 40  ? -9.397  7.640   -1.105  1.000 8.906  0 35   VAL A C    1 ? 
ATOM   573  O O    . VAL A 1 40  ? -9.324  6.744   -0.249  1.000 8.950  0 35   VAL A O    1 ? 
ATOM   574  C CB   . VAL A 1 40  ? -7.323  8.804   -1.993  1.000 10.739 0 35   VAL A CB   1 ? 
ATOM   575  C CG1  . VAL A 1 40  ? -6.679  8.716   -0.614  1.000 11.918 0 35   VAL A CG1  1 ? 
ATOM   576  C CG2  . VAL A 1 40  ? -6.261  8.727   -3.063  1.000 11.669 0 35   VAL A CG2  1 ? 
ATOM   577  H H    . VAL A 1 40  ? -8.949  8.669   -3.967  1.000 8.740  0 35   VAL A H    1 c 
ATOM   578  H HA   . VAL A 1 40  ? -7.906  6.857   -2.280  1.000 9.252  0 35   VAL A HA   1 c 
ATOM   579  H HB   . VAL A 1 40  ? -7.780  9.674   -2.070  1.000 10.765 0 35   VAL A HB   1 c 
ATOM   580  H HG11 . VAL A 1 40  ? -6.371  7.808   -0.456  1.000 11.554 0 35   VAL A HG11 1 c 
ATOM   581  H HG12 . VAL A 1 40  ? -7.329  8.960   0.066   1.000 11.542 0 35   VAL A HG12 1 c 
ATOM   582  H HG13 . VAL A 1 40  ? -5.923  9.326   -0.570  1.000 11.553 0 35   VAL A HG13 1 c 
ATOM   583  H HG21 . VAL A 1 40  ? -5.561  9.374   -2.874  1.000 11.373 0 35   VAL A HG21 1 c 
ATOM   584  H HG22 . VAL A 1 40  ? -6.655  8.923   -3.929  1.000 11.342 0 35   VAL A HG22 1 c 
ATOM   585  H HG23 . VAL A 1 40  ? -5.878  7.833   -3.077  1.000 11.360 0 35   VAL A HG23 1 c 
ATOM   586  N N    . LEU A 1 41  ? -10.329 8.607   -1.061  1.000 8.642  0 36   LEU A N    1 ? 
ATOM   587  C CA   . LEU A 1 41  ? -11.346 8.599   -0.035  1.000 8.674  0 36   LEU A CA   1 ? 
ATOM   588  C C    . LEU A 1 41  ? -12.092 7.278   -0.049  1.000 8.583  0 36   LEU A C    1 ? 
ATOM   589  O O    . LEU A 1 41  ? -12.346 6.676   1.003   1.000 9.317  0 36   LEU A O    1 ? 
ATOM   590  C CB   . LEU A 1 41  ? -12.318 9.758   -0.255  1.000 9.916  0 36   LEU A CB   1 ? 
ATOM   591  C CG   . LEU A 1 41  ? -13.485 9.849   0.737   1.000 10.917 0 36   LEU A CG   1 ? 
ATOM   592  C CD1  . LEU A 1 41  ? -13.008 9.995   2.168   1.000 11.826 0 36   LEU A CD1  1 ? 
ATOM   593  C CD2  . LEU A 1 41  ? -14.448 10.963  0.314   1.000 11.717 0 36   LEU A CD2  1 ? 
ATOM   594  H H    . LEU A 1 41  ? -10.322 9.280   -1.679  1.000 8.733  0 36   LEU A H    1 c 
ATOM   595  H HA   . LEU A 1 41  ? -10.902 8.705   0.845   1.000 8.890  0 36   LEU A HA   1 c 
ATOM   596  H HB2  . LEU A 1 41  ? -11.807 10.599  -0.211  1.000 9.829  0 36   LEU A HB2  1 c 
ATOM   597  H HB3  . LEU A 1 41  ? -12.688 9.680   -1.164  1.000 9.832  0 36   LEU A HB3  1 c 
ATOM   598  H HG   . LEU A 1 41  ? -13.990 8.997   0.685   1.000 11.018 0 36   LEU A HG   1 c 
ATOM   599  H HD11 . LEU A 1 41  ? -12.566 9.177   2.450   1.000 11.521 0 36   LEU A HD11 1 c 
ATOM   600  H HD12 . LEU A 1 41  ? -13.769 10.166  2.748   1.000 11.550 0 36   LEU A HD12 1 c 
ATOM   601  H HD13 . LEU A 1 41  ? -12.384 10.737  2.229   1.000 11.581 0 36   LEU A HD13 1 c 
ATOM   602  H HD21 . LEU A 1 41  ? -14.798 10.771  -0.572  1.000 11.476 0 36   LEU A HD21 1 c 
ATOM   603  H HD22 . LEU A 1 41  ? -13.976 11.812  0.299   1.000 11.476 0 36   LEU A HD22 1 c 
ATOM   604  H HD23 . LEU A 1 41  ? -15.184 11.014  0.947   1.000 11.476 0 36   LEU A HD23 1 c 
ATOM   605  N N    . LEU A 1 42  ? -12.581 6.933   -1.250  1.000 8.463  0 37   LEU A N    1 ? 
ATOM   606  C CA   . LEU A 1 42  ? -13.453 5.772   -1.367  1.000 7.622  0 37   LEU A CA   1 ? 
ATOM   607  C C    . LEU A 1 42  ? -12.758 4.471   -0.994  1.000 8.135  0 37   LEU A C    1 ? 
ATOM   608  O O    . LEU A 1 42  ? -13.338 3.596   -0.325  1.000 8.555  0 37   LEU A O    1 ? 
ATOM   609  C CB   . LEU A 1 42  ? -14.098 5.724   -2.757  1.000 8.209  0 37   LEU A CB   1 ? 
ATOM   610  C CG   . LEU A 1 42  ? -15.031 6.898   -3.077  1.000 8.868  0 37   LEU A CG   1 ? 
ATOM   611  C CD1  . LEU A 1 42  ? -15.414 6.873   -4.564  1.000 9.745  0 37   LEU A CD1  1 ? 
ATOM   612  C CD2  . LEU A 1 42  ? -16.285 6.861   -2.187  1.000 9.853  0 37   LEU A CD2  1 ? 
ATOM   613  H H    . LEU A 1 42  ? -12.375 7.419   -1.996  1.000 8.304  0 37   LEU A H    1 c 
ATOM   614  H HA   . LEU A 1 42  ? -14.178 5.896   -0.704  1.000 8.008  0 37   LEU A HA   1 c 
ATOM   615  H HB2  . LEU A 1 42  ? -13.380 5.702   -3.431  1.000 8.214  0 37   LEU A HB2  1 c 
ATOM   616  H HB3  . LEU A 1 42  ? -14.612 4.887   -2.831  1.000 8.215  0 37   LEU A HB3  1 c 
ATOM   617  H HG   . LEU A 1 42  ? -14.546 7.743   -2.895  1.000 9.061  0 37   LEU A HG   1 c 
ATOM   618  H HD11 . LEU A 1 42  ? -14.611 6.945   -5.108  1.000 9.480  0 37   LEU A HD11 1 c 
ATOM   619  H HD12 . LEU A 1 42  ? -16.005 7.620   -4.760  1.000 9.480  0 37   LEU A HD12 1 c 
ATOM   620  H HD13 . LEU A 1 42  ? -15.869 6.039   -4.768  1.000 9.480  0 37   LEU A HD13 1 c 
ATOM   621  H HD21 . LEU A 1 42  ? -16.037 7.052   -1.266  1.000 9.534  0 37   LEU A HD21 1 c 
ATOM   622  H HD22 . LEU A 1 42  ? -16.692 5.980   -2.235  1.000 9.548  0 37   LEU A HD22 1 c 
ATOM   623  H HD23 . LEU A 1 42  ? -16.921 7.528   -2.494  1.000 9.563  0 37   LEU A HD23 1 c 
ATOM   624  N N    . SER A 1 43  ? -11.503 4.289   -1.422  1.000 7.916  0 38   SER A N    1 ? 
ATOM   625  C CA   . SER A 1 43  ? -10.771 3.077   -1.120  1.000 7.445  0 38   SER A CA   1 ? 
ATOM   626  C C    . SER A 1 43  ? -10.467 2.990   0.381   1.000 8.225  0 38   SER A C    1 ? 
ATOM   627  O O    . SER A 1 43  ? -10.469 1.878   0.954   1.000 7.913  0 38   SER A O    1 ? 
ATOM   628  C CB   . SER A 1 43  ? -9.522  2.996   -1.948  1.000 7.623  0 38   SER A CB   1 ? 
ATOM   629  O OG   . SER A 1 43  ? -8.757  1.831   -1.639  1.000 7.987  0 38   SER A OG   1 ? 
ATOM   630  H H    . SER A 1 43  ? -11.095 4.940   -1.918  1.000 7.858  0 38   SER A H    1 c 
ATOM   631  H HA   . SER A 1 43  ? -11.347 2.307   -1.359  1.000 7.713  0 38   SER A HA   1 c 
ATOM   632  H HB2  . SER A 1 43  ? -9.765  2.982   -2.893  1.000 7.667  0 38   SER A HB2  1 c 
ATOM   633  H HB3  . SER A 1 43  ? -8.979  3.791   -1.787  1.000 7.667  0 38   SER A HB3  1 c 
ATOM   634  H HG   . SER A 1 43  ? -8.066  1.826   -2.127  0.000 7.990  0 38   SER A HG   1 c 
ATOM   635  N N    . LEU A 1 44  ? -10.121 4.131   1.004   1.000 8.287  0 39   LEU A N    1 ? 
ATOM   636  C CA   . LEU A 1 44  ? -9.894  4.138   2.457   1.000 8.257  0 39   LEU A CA   1 ? 
ATOM   637  C C    . LEU A 1 44  ? -11.159 3.748   3.217   1.000 8.237  0 39   LEU A C    1 ? 
ATOM   638  O O    . LEU A 1 44  ? -11.059 2.981   4.174   1.000 8.875  0 39   LEU A O    1 ? 
ATOM   639  C CB   . LEU A 1 44  ? -9.380  5.490   2.924   1.000 9.834  0 39   LEU A CB   1 ? 
ATOM   640  C CG   . LEU A 1 44  ? -7.938  5.807   2.518   1.000 10.097 0 39   LEU A CG   1 ? 
ATOM   641  C CD1  . LEU A 1 44  ? -7.604  7.269   2.809   1.000 10.907 0 39   LEU A CD1  1 ? 
ATOM   642  C CD2  . LEU A 1 44  ? -6.936  4.883   3.241   1.000 10.323 0 39   LEU A CD2  1 ? 
ATOM   643  H H    . LEU A 1 44  ? -10.019 4.905   0.530   1.000 8.276  0 39   LEU A H    1 c 
ATOM   644  H HA   . LEU A 1 44  ? -9.206  3.454   2.653   1.000 8.545  0 39   LEU A HA   1 c 
ATOM   645  H HB2  . LEU A 1 44  ? -9.969  6.189   2.556   1.000 9.494  0 39   LEU A HB2  1 c 
ATOM   646  H HB3  . LEU A 1 44  ? -9.442  5.523   3.907   1.000 9.495  0 39   LEU A HB3  1 c 
ATOM   647  H HG   . LEU A 1 44  ? -7.848  5.655   1.542   1.000 10.227 0 39   LEU A HG   1 c 
ATOM   648  H HD11 . LEU A 1 44  ? -8.206  7.845   2.308   1.000 10.663 0 39   LEU A HD11 1 c 
ATOM   649  H HD12 . LEU A 1 44  ? -6.687  7.451   2.544   1.000 10.664 0 39   LEU A HD12 1 c 
ATOM   650  H HD13 . LEU A 1 44  ? -7.707  7.442   3.759   1.000 10.663 0 39   LEU A HD13 1 c 
ATOM   651  H HD21 . LEU A 1 44  ? -7.066  3.967   2.947   1.000 10.215 0 39   LEU A HD21 1 c 
ATOM   652  H HD22 . LEU A 1 44  ? -7.078  4.937   4.201   1.000 10.247 0 39   LEU A HD22 1 c 
ATOM   653  H HD23 . LEU A 1 44  ? -6.028  5.162   3.033   1.000 10.247 0 39   LEU A HD23 1 c 
ATOM   654  N N    . VAL A 1 45  ? -12.316 4.242   2.807   1.000 8.283  0 40   VAL A N    1 ? 
ATOM   655  C CA   . VAL A 1 45  ? -13.566 3.888   3.471   1.000 9.109  0 40   VAL A CA   1 ? 
ATOM   656  C C    . VAL A 1 45  ? -13.818 2.396   3.293   1.000 9.166  0 40   VAL A C    1 ? 
ATOM   657  O O    . VAL A 1 45  ? -14.147 1.719   4.250   1.000 9.432  0 40   VAL A O    1 ? 
ATOM   658  C CB   . VAL A 1 45  ? -14.713 4.759   2.947   1.000 9.137  0 40   VAL A CB   1 ? 
ATOM   659  C CG1  . VAL A 1 45  ? -16.077 4.199   3.337   1.000 9.455  0 40   VAL A CG1  1 ? 
ATOM   660  C CG2  . VAL A 1 45  ? -14.561 6.221   3.415   1.000 10.311 0 40   VAL A CG2  1 ? 
ATOM   661  H H    . VAL A 1 45  ? -12.338 4.820   2.099   1.000 8.460  0 40   VAL A H    1 c 
ATOM   662  H HA   . VAL A 1 45  ? -13.461 4.068   4.426   1.000 8.956  0 40   VAL A HA   1 c 
ATOM   663  H HB   . VAL A 1 45  ? -14.657 4.752   1.963   1.000 9.391  0 40   VAL A HB   1 c 
ATOM   664  H HG11 . VAL A 1 45  ? -16.070 3.949   4.276   1.000 9.360  0 40   VAL A HG11 1 c 
ATOM   665  H HG12 . VAL A 1 45  ? -16.276 3.417   2.795   1.000 9.360  0 40   VAL A HG12 1 c 
ATOM   666  H HG13 . VAL A 1 45  ? -16.760 4.875   3.188   1.000 9.365  0 40   VAL A HG13 1 c 
ATOM   667  H HG21 . VAL A 1 45  ? -15.243 6.770   2.992   1.000 9.951  0 40   VAL A HG21 1 c 
ATOM   668  H HG22 . VAL A 1 45  ? -13.682 6.552   3.169   1.000 9.941  0 40   VAL A HG22 1 c 
ATOM   669  H HG23 . VAL A 1 45  ? -14.664 6.265   4.381   1.000 9.951  0 40   VAL A HG23 1 c 
ATOM   670  N N    . LEU A 1 46  ? -13.752 1.865   2.048   1.000 8.186  0 41   LEU A N    1 ? 
ATOM   671  C CA   . LEU A 1 46  ? -13.993 0.445   1.880   1.000 8.467  0 41   LEU A CA   1 ? 
ATOM   672  C C    . LEU A 1 46  ? -13.033 -0.385  2.720   1.000 8.827  0 41   LEU A C    1 ? 
ATOM   673  O O    . LEU A 1 46  ? -13.434 -1.404  3.278   1.000 8.858  0 41   LEU A O    1 ? 
ATOM   674  C CB   . LEU A 1 46  ? -13.908 0.026   0.401   1.000 8.342  0 41   LEU A CB   1 ? 
ATOM   675  C CG   . LEU A 1 46  ? -15.027 0.542   -0.503  1.000 8.902  0 41   LEU A CG   1 ? 
ATOM   676  C CD1  . LEU A 1 46  ? -14.843 0.038   -1.924  1.000 9.996  0 41   LEU A CD1  1 ? 
ATOM   677  C CD2  . LEU A 1 46  ? -16.411 0.141   0.013   1.000 9.942  0 41   LEU A CD2  1 ? 
ATOM   678  H H    . LEU A 1 46  ? -13.562 2.386   1.321   1.000 8.472  0 41   LEU A H    1 c 
ATOM   679  H HA   . LEU A 1 46  ? -14.908 0.259   2.207   1.000 8.479  0 41   LEU A HA   1 c 
ATOM   680  H HB2  . LEU A 1 46  ? -13.047 0.342   0.041   1.000 8.496  0 41   LEU A HB2  1 c 
ATOM   681  H HB3  . LEU A 1 46  ? -13.905 -0.958  0.360   1.000 8.497  0 41   LEU A HB3  1 c 
ATOM   682  H HG   . LEU A 1 46  ? -14.979 1.531   -0.517  1.000 9.167  0 41   LEU A HG   1 c 
ATOM   683  H HD11 . LEU A 1 46  ? -13.987 0.343   -2.269  1.000 9.645  0 41   LEU A HD11 1 c 
ATOM   684  H HD12 . LEU A 1 46  ? -15.558 0.381   -2.486  1.000 9.650  0 41   LEU A HD12 1 c 
ATOM   685  H HD13 . LEU A 1 46  ? -14.866 -0.934  -1.930  1.000 9.655  0 41   LEU A HD13 1 c 
ATOM   686  H HD21 . LEU A 1 46  ? -16.631 0.667   0.800   1.000 9.610  0 41   LEU A HD21 1 c 
ATOM   687  H HD22 . LEU A 1 46  ? -16.410 -0.804  0.245   1.000 9.622  0 41   LEU A HD22 1 c 
ATOM   688  H HD23 . LEU A 1 46  ? -17.075 0.302   -0.679  1.000 9.623  0 41   LEU A HD23 1 c 
ATOM   689  N N    . GLY A 1 47  ? -11.746 -0.044  2.687   1.000 8.197  0 42   GLY A N    1 ? 
ATOM   690  C CA   . GLY A 1 47  ? -10.768 -0.804  3.438   1.000 8.361  0 42   GLY A CA   1 ? 
ATOM   691  C C    . GLY A 1 47  ? -10.984 -0.800  4.946   1.000 8.273  0 42   GLY A C    1 ? 
ATOM   692  O O    . GLY A 1 47  ? -10.761 -1.815  5.607   1.000 8.362  0 42   GLY A O    1 ? 
ATOM   693  H H    . GLY A 1 47  ? -11.471 0.669   2.186   1.000 8.379  0 42   GLY A H    1 c 
ATOM   694  H HA2  . GLY A 1 47  ? -10.784 -1.735  3.116   1.000 8.331  0 42   GLY A HA2  1 c 
ATOM   695  H HA3  . GLY A 1 47  ? -9.877  -0.440  3.241   1.000 8.326  0 42   GLY A HA3  1 c 
ATOM   696  N N    . PHE A 1 48  ? -11.359 0.363   5.448   1.000 7.701  0 43   PHE A N    1 ? 
ATOM   697  C CA   . PHE A 1 48  ? -11.735 0.511   6.848   1.000 8.046  0 43   PHE A CA   1 ? 
ATOM   698  C C    . PHE A 1 48  ? -12.893 -0.421  7.198   1.000 8.652  0 43   PHE A C    1 ? 
ATOM   699  O O    . PHE A 1 48  ? -12.823 -1.207  8.158   1.000 9.083  0 43   PHE A O    1 ? 
ATOM   700  C CB   . PHE A 1 48  ? -12.060 1.963   7.118   1.000 8.900  0 43   PHE A CB   1 ? 
ATOM   701  C CG   . PHE A 1 48  ? -12.607 2.197   8.522   1.000 9.254  0 43   PHE A CG   1 ? 
ATOM   702  C CD1  . PHE A 1 48  ? -11.762 2.469   9.593   1.000 9.949  0 43   PHE A CD1  1 ? 
ATOM   703  C CD2  . PHE A 1 48  ? -13.974 2.131   8.766   1.000 10.130 0 43   PHE A CD2  1 ? 
ATOM   704  C CE1  . PHE A 1 48  ? -12.283 2.710   10.868  1.000 11.970 0 43   PHE A CE1  1 ? 
ATOM   705  C CE2  . PHE A 1 48  ? -14.484 2.356   10.044  1.000 9.784  0 43   PHE A CE2  1 ? 
ATOM   706  C CZ   . PHE A 1 48  ? -13.647 2.612   11.086  1.000 10.934 0 43   PHE A CZ   1 ? 
ATOM   707  H H    . PHE A 1 48  ? -11.377 1.100   4.908   1.000 7.929  0 43   PHE A H    1 c 
ATOM   708  H HA   . PHE A 1 48  ? -10.952 0.258   7.406   1.000 8.236  0 43   PHE A HA   1 c 
ATOM   709  H HB2  . PHE A 1 48  ? -11.243 2.497   6.998   1.000 8.772  0 43   PHE A HB2  1 c 
ATOM   710  H HB3  . PHE A 1 48  ? -12.724 2.266   6.460   1.000 8.770  0 43   PHE A HB3  1 c 
ATOM   711  H HD1  . PHE A 1 48  ? -10.831 2.528   9.448   1.000 10.211 0 43   PHE A HD1  1 c 
ATOM   712  H HD2  . PHE A 1 48  ? -14.564 1.943   8.054   1.000 9.845  0 43   PHE A HD2  1 c 
ATOM   713  H HE1  . PHE A 1 48  ? -11.701 2.885   11.589  1.000 11.193 0 43   PHE A HE1  1 c 
ATOM   714  H HE2  . PHE A 1 48  ? -15.414 2.302   10.193  1.000 10.145 0 43   PHE A HE2  1 c 
ATOM   715  H HZ   . PHE A 1 48  ? -14.001 2.769   11.947  1.000 10.963 0 43   PHE A HZ   1 c 
ATOM   716  N N    A VAL A 1 49  ? -13.989 -0.418  6.428   0.500 8.465  0 44   VAL A N    1 ? 
ATOM   717  N N    B VAL A 1 49  ? -13.977 -0.284  6.430   0.500 8.823  0 44   VAL A N    1 ? 
ATOM   718  C CA   A VAL A 1 49  ? -15.129 -1.216  6.860   0.500 8.562  0 44   VAL A CA   1 ? 
ATOM   719  C CA   B VAL A 1 49  ? -15.169 -1.069  6.669   0.500 9.314  0 44   VAL A CA   1 ? 
ATOM   720  C C    A VAL A 1 49  ? -14.817 -2.692  6.597   0.500 8.609  0 44   VAL A C    1 ? 
ATOM   721  C C    B VAL A 1 49  ? -14.856 -2.569  6.556   0.500 8.993  0 44   VAL A C    1 ? 
ATOM   722  O O    A VAL A 1 49  ? -15.174 -3.581  7.385   0.500 9.049  0 44   VAL A O    1 ? 
ATOM   723  O O    B VAL A 1 49  ? -15.331 -3.328  7.411   0.500 10.294 0 44   VAL A O    1 ? 
ATOM   724  C CB   A VAL A 1 49  ? -16.452 -0.724  6.233   0.500 8.207  0 44   VAL A CB   1 ? 
ATOM   725  C CB   B VAL A 1 49  ? -16.288 -0.602  5.720   0.500 9.679  0 44   VAL A CB   1 ? 
ATOM   726  C CG1  A VAL A 1 49  ? -16.641 0.765   6.513   0.500 8.405  0 44   VAL A CG1  1 ? 
ATOM   727  C CG1  B VAL A 1 49  ? -17.454 -1.579  5.692   0.500 9.965  0 44   VAL A CG1  1 ? 
ATOM   728  C CG2  A VAL A 1 49  ? -16.536 -1.052  4.750   0.500 8.027  0 44   VAL A CG2  1 ? 
ATOM   729  C CG2  B VAL A 1 49  ? -16.739 0.820   6.061   0.500 10.213 0 44   VAL A CG2  1 ? 
ATOM   730  H H    A VAL A 1 49  ? -14.031 0.067   5.655   0.500 8.526  0 44   VAL A H    1 c 
ATOM   731  H H    B VAL A 1 49  ? -13.973 0.317   5.741   0.500 8.876  0 44   VAL A H    1 c 
ATOM   732  H HA   A VAL A 1 49  ? -15.213 -1.104  7.828   0.500 8.490  0 44   VAL A HA   1 c 
ATOM   733  H HA   B VAL A 1 49  ? -15.460 -0.893  7.584   0.500 9.218  0 44   VAL A HA   1 c 
ATOM   734  H HB   A VAL A 1 49  ? -17.182 -1.207  6.686   0.500 8.274  0 44   VAL A HB   1 c 
ATOM   735  H HB   B VAL A 1 49  ? -15.903 -0.578  4.812   0.500 9.760  0 44   VAL A HB   1 c 
ATOM   736  H HG11 A VAL A 1 49  ? -15.884 1.261   6.160   0.500 8.352  0 44   VAL A HG11 1 c 
ATOM   737  H HG11 B VAL A 1 49  ? -17.785 -1.716  6.595   0.500 9.891  0 44   VAL A HG11 1 c 
ATOM   738  H HG12 A VAL A 1 49  ? -16.704 0.910   7.472   0.500 8.348  0 44   VAL A HG12 1 c 
ATOM   739  H HG12 B VAL A 1 49  ? -17.156 -2.428  5.324   0.500 9.887  0 44   VAL A HG12 1 c 
ATOM   740  H HG13 A VAL A 1 49  ? -17.458 1.074   6.086   0.500 8.348  0 44   VAL A HG13 1 c 
ATOM   741  H HG13 B VAL A 1 49  ? -18.167 -1.219  5.137   0.500 9.883  0 44   VAL A HG13 1 c 
ATOM   742  H HG21 A VAL A 1 49  ? -17.384 -0.736  4.395   0.500 8.081  0 44   VAL A HG21 1 c 
ATOM   743  H HG21 B VAL A 1 49  ? -17.380 1.126   5.397   0.500 10.052 0 44   VAL A HG21 1 c 
ATOM   744  H HG22 A VAL A 1 49  ? -16.472 -2.013  4.625   0.500 8.082  0 44   VAL A HG22 1 c 
ATOM   745  H HG22 B VAL A 1 49  ? -15.969 1.413   6.065   0.500 10.049 0 44   VAL A HG22 1 c 
ATOM   746  H HG23 A VAL A 1 49  ? -15.806 -0.615  4.279   0.500 8.084  0 44   VAL A HG23 1 c 
ATOM   747  H HG23 B VAL A 1 49  ? -17.155 0.826   6.939   0.500 10.052 0 44   VAL A HG23 1 c 
ATOM   748  N N    . GLU A 1 50  ? -14.095 -3.013  5.531   1.000 8.299  0 45   GLU A N    1 ? 
ATOM   749  C CA   . GLU A 1 50  ? -13.725 -4.407  5.340   1.000 8.475  0 45   GLU A CA   1 ? 
ATOM   750  C C    . GLU A 1 50  ? -12.845 -4.878  6.487   1.000 8.460  0 45   GLU A C    1 ? 
ATOM   751  O O    . GLU A 1 50  ? -12.924 -6.043  6.897   1.000 9.822  0 45   GLU A O    1 ? 
ATOM   752  C CB   . GLU A 1 50  ? -13.077 -4.580  3.949   1.000 8.604  0 45   GLU A CB   1 ? 
ATOM   753  C CG   . GLU A 1 50  ? -12.505 -5.965  3.705   1.000 9.421  0 45   GLU A CG   1 ? 
ATOM   754  C CD   . GLU A 1 50  ? -12.197 -6.256  2.258   1.000 9.309  0 45   GLU A CD   1 ? 
ATOM   755  O OE1  . GLU A 1 50  ? -12.972 -5.787  1.377   1.000 9.779  0 45   GLU A OE1  1 ? 
ATOM   756  O OE2  . GLU A 1 50  ? -11.258 -7.065  1.994   1.000 9.417  0 45   GLU A OE2  1 ? 
ATOM   757  H H    . GLU A 1 50  ? -13.817 -2.390  4.923   1.000 8.528  0 45   GLU A H    1 c 
ATOM   758  H HA   . GLU A 1 50  ? -14.555 -4.947  5.350   1.000 8.476  0 45   GLU A HA   1 c 
ATOM   759  H HB2  . GLU A 1 50  ? -13.750 -4.383  3.265   1.000 8.763  0 45   GLU A HB2  1 c 
ATOM   760  H HB3  . GLU A 1 50  ? -12.356 -3.922  3.855   1.000 8.756  0 45   GLU A HB3  1 c 
ATOM   761  H HG2  . GLU A 1 50  ? -11.679 -6.067  4.224   1.000 9.200  0 45   GLU A HG2  1 c 
ATOM   762  H HG3  . GLU A 1 50  ? -13.143 -6.636  4.029   1.000 9.203  0 45   GLU A HG3  1 c 
ATOM   763  N N    . HIS A 1 51  ? -11.917 -4.061  6.953   1.000 9.012  0 46   HIS A N    1 ? 
ATOM   764  C CA   . HIS A 1 51  ? -11.082 -4.485  8.068   1.000 8.969  0 46   HIS A CA   1 ? 
ATOM   765  C C    . HIS A 1 51  ? -11.933 -4.900  9.285   1.000 9.157  0 46   HIS A C    1 ? 
ATOM   766  O O    . HIS A 1 51  ? -11.692 -5.954  9.903   1.000 10.907 0 46   HIS A O    1 ? 
ATOM   767  C CB   . HIS A 1 51  ? -10.057 -3.419  8.483   1.000 9.734  0 46   HIS A CB   1 ? 
ATOM   768  C CG   . HIS A 1 51  ? -9.165  -3.869  9.600   1.000 10.683 0 46   HIS A CG   1 ? 
ATOM   769  N ND1  . HIS A 1 51  ? -8.015  -4.602  9.400   1.000 11.318 0 46   HIS A ND1  1 ? 
ATOM   770  C CD2  . HIS A 1 51  ? -9.327  -3.738  10.922  1.000 11.886 0 46   HIS A CD2  1 ? 
ATOM   771  C CE1  . HIS A 1 51  ? -7.521  -4.880  10.628  1.000 11.447 0 46   HIS A CE1  1 ? 
ATOM   772  N NE2  . HIS A 1 51  ? -8.284  -4.397  11.532  1.000 12.905 0 46   HIS A NE2  1 ? 
ATOM   773  H H    . HIS A 1 51  ? -11.789 -3.237  6.581   1.000 8.866  0 46   HIS A H    1 c 
ATOM   774  H HA   . HIS A 1 51  ? -10.578 -5.281  7.765   1.000 9.148  0 46   HIS A HA   1 c 
ATOM   775  H HB2  . HIS A 1 51  ? -9.504  -3.191  7.704   1.000 9.765  0 46   HIS A HB2  1 c 
ATOM   776  H HB3  . HIS A 1 51  ? -10.537 -2.610  8.763   1.000 9.765  0 46   HIS A HB3  1 c 
ATOM   777  H HD1  . HIS A 1 51  ? -7.709  -4.865  8.616   0.000 11.320 0 46   HIS A HD1  1 c 
ATOM   778  H HD2  . HIS A 1 51  ? -10.035 -3.307  11.358  1.000 11.813 0 46   HIS A HD2  1 c 
ATOM   779  H HE1  . HIS A 1 51  ? -6.723  -5.357  10.784  1.000 11.739 0 46   HIS A HE1  1 c 
ATOM   780  H HE2  . HIS A 1 51  ? -8.153  -4.461  12.398  0.000 12.910 0 46   HIS A HE2  1 c 
ATOM   781  N N    . PHE A 1 52  ? -12.900 -4.041  9.638   1.000 9.615  0 47   PHE A N    1 ? 
ATOM   782  C CA   . PHE A 1 52  ? -13.677 -4.273  10.854  1.000 10.073 0 47   PHE A CA   1 ? 
ATOM   783  C C    . PHE A 1 52  ? -14.862 -5.193  10.618  1.000 10.226 0 47   PHE A C    1 ? 
ATOM   784  O O    . PHE A 1 52  ? -15.513 -5.589  11.594  1.000 12.671 0 47   PHE A O    1 ? 
ATOM   785  C CB   . PHE A 1 52  ? -14.009 -2.892  11.415  1.000 10.601 0 47   PHE A CB   1 ? 
ATOM   786  C CG   . PHE A 1 52  ? -12.789 -2.185  11.974  1.000 11.244 0 47   PHE A CG   1 ? 
ATOM   787  C CD1  . PHE A 1 52  ? -12.187 -2.703  13.121  1.000 13.019 0 47   PHE A CD1  1 ? 
ATOM   788  C CD2  . PHE A 1 52  ? -12.254 -1.032  11.421  1.000 12.145 0 47   PHE A CD2  1 ? 
ATOM   789  C CE1  . PHE A 1 52  ? -11.078 -2.103  13.647  1.000 13.843 0 47   PHE A CE1  1 ? 
ATOM   790  C CE2  . PHE A 1 52  ? -11.102 -0.465  11.924  1.000 13.247 0 47   PHE A CE2  1 ? 
ATOM   791  C CZ   . PHE A 1 52  ? -10.528 -0.978  13.064  1.000 14.460 0 47   PHE A CZ   1 ? 
ATOM   792  H H    . PHE A 1 52  ? -13.079 -3.308  9.122   1.000 9.609  0 47   PHE A H    1 c 
ATOM   793  H HA   . PHE A 1 52  ? -13.080 -4.722  11.509  1.000 10.137 0 47   PHE A HA   1 c 
ATOM   794  H HB2  . PHE A 1 52  ? -14.401 -2.344  10.699  1.000 10.615 0 47   PHE A HB2  1 c 
ATOM   795  H HB3  . PHE A 1 52  ? -14.676 -2.994  12.129  1.000 10.629 0 47   PHE A HB3  1 c 
ATOM   796  H HD1  . PHE A 1 52  ? -12.541 -3.479  13.526  1.000 12.814 0 47   PHE A HD1  1 c 
ATOM   797  H HD2  . PHE A 1 52  ? -12.633 -0.683  10.631  1.000 12.174 0 47   PHE A HD2  1 c 
ATOM   798  H HE1  . PHE A 1 52  ? -10.674 -2.470  14.416  1.000 13.746 0 47   PHE A HE1  1 c 
ATOM   799  H HE2  . PHE A 1 52  ? -10.755 0.321   11.534  1.000 13.234 0 47   PHE A HE2  1 c 
ATOM   800  H HZ   . PHE A 1 52  ? -9.764  -0.571  13.439  1.000 13.981 0 47   PHE A HZ   1 c 
ATOM   801  N N    . LEU A 1 53  ? -15.142 -5.627  9.378   1.000 10.399 0 48   LEU A N    1 ? 
ATOM   802  C CA   . LEU A 1 53  ? -16.177 -6.607  9.109   1.000 10.398 0 48   LEU A CA   1 ? 
ATOM   803  C C    . LEU A 1 53  ? -15.622 -7.963  8.753   1.000 11.098 0 48   LEU A C    1 ? 
ATOM   804  O O    . LEU A 1 53  ? -16.346 -8.938  8.825   1.000 12.742 0 48   LEU A O    1 ? 
ATOM   805  C CB   . LEU A 1 53  ? -17.163 -6.114  8.037   1.000 10.259 0 48   LEU A CB   1 ? 
ATOM   806  C CG   . LEU A 1 53  ? -18.091 -4.994  8.459   1.000 10.072 0 48   LEU A CG   1 ? 
ATOM   807  C CD1  . LEU A 1 53  ? -18.739 -4.329  7.267   1.000 10.918 0 48   LEU A CD1  1 ? 
ATOM   808  C CD2  . LEU A 1 53  ? -19.128 -5.510  9.415   1.000 10.674 0 48   LEU A CD2  1 ? 
ATOM   809  H H    . LEU A 1 53  ? -14.680 -5.279  8.671   1.000 10.336 0 48   LEU A H    1 c 
ATOM   810  H HA   . LEU A 1 53  ? -16.684 -6.729  9.950   1.000 10.514 0 48   LEU A HA   1 c 
ATOM   811  H HB2  . LEU A 1 53  ? -16.643 -5.811  7.258   1.000 10.250 0 48   LEU A HB2  1 c 
ATOM   812  H HB3  . LEU A 1 53  ? -17.712 -6.880  7.748   1.000 10.266 0 48   LEU A HB3  1 c 
ATOM   813  H HG   . LEU A 1 53  ? -17.552 -4.310  8.934   1.000 10.373 0 48   LEU A HG   1 c 
ATOM   814  H HD11 . LEU A 1 53  ? -18.059 -4.103  6.612   1.000 10.642 0 48   LEU A HD11 1 c 
ATOM   815  H HD12 . LEU A 1 53  ? -19.194 -3.519  7.554   1.000 10.655 0 48   LEU A HD12 1 c 
ATOM   816  H HD13 . LEU A 1 53  ? -19.384 -4.936  6.866   1.000 10.655 0 48   LEU A HD13 1 c 
ATOM   817  H HD21 . LEU A 1 53  ? -18.699 -5.791  10.240  1.000 10.491 0 48   LEU A HD21 1 c 
ATOM   818  H HD22 . LEU A 1 53  ? -19.590 -6.267  9.016   1.000 10.492 0 48   LEU A HD22 1 c 
ATOM   819  H HD23 . LEU A 1 53  ? -19.770 -4.806  9.609   1.000 10.491 0 48   LEU A HD23 1 c 
ATOM   820  N N    . ALA A 1 54  ? -14.371 -8.059  8.259   1.000 10.121 0 49   ALA A N    1 ? 
ATOM   821  C CA   . ALA A 1 54  ? -13.808 -9.325  7.828   1.000 11.443 0 49   ALA A CA   1 ? 
ATOM   822  C C    . ALA A 1 54  ? -12.494 -9.668  8.515   1.000 13.376 0 49   ALA A C    1 ? 
ATOM   823  O O    . ALA A 1 54  ? -12.238 -10.854 8.711   1.000 17.018 0 49   ALA A O    1 ? 
ATOM   824  C CB   . ALA A 1 54  ? -13.646 -9.386  6.320   1.000 11.814 0 49   ALA A CB   1 ? 
ATOM   825  H H    . ALA A 1 54  ? -13.863 -7.304  8.177   1.000 10.669 0 49   ALA A H    1 c 
ATOM   826  H HA   . ALA A 1 54  ? -14.456 -10.034 8.086   1.000 11.629 0 49   ALA A HA   1 c 
ATOM   827  H HB1  . ALA A 1 54  ? -14.518 -9.328  5.894   1.000 11.707 0 49   ALA A HB1  1 c 
ATOM   828  H HB2  . ALA A 1 54  ? -13.093 -8.644  6.020   1.000 11.707 0 49   ALA A HB2  1 c 
ATOM   829  H HB3  . ALA A 1 54  ? -13.222 -10.223 6.070   1.000 11.719 0 49   ALA A HB3  1 c 
ATOM   830  N N    . VAL A 1 55  ? -11.618 -8.706  8.787   1.000 13.593 0 50   VAL A N    1 ? 
ATOM   831  C CA   . VAL A 1 55  ? -10.325 -9.014  9.367   1.000 13.279 0 50   VAL A CA   1 ? 
ATOM   832  C C    . VAL A 1 55  ? -10.447 -9.139  10.874  1.000 13.785 0 50   VAL A C    1 ? 
ATOM   833  O O    . VAL A 1 55  ? -9.892  -10.099 11.430  1.000 17.913 0 50   VAL A O    1 ? 
ATOM   834  C CB   . VAL A 1 55  ? -9.259  -7.986  8.957   1.000 12.232 0 50   VAL A CB   1 ? 
ATOM   835  C CG1  . VAL A 1 55  ? -7.908  -8.251  9.628   1.000 13.522 0 50   VAL A CG1  1 ? 
ATOM   836  C CG2  . VAL A 1 55  ? -9.120  -7.984  7.438   1.000 13.494 0 50   VAL A CG2  1 ? 
ATOM   837  H H    . VAL A 1 55  ? -11.823 -7.835  8.603   1.000 13.394 0 50   VAL A H    1 c 
ATOM   838  H HA   . VAL A 1 55  ? -10.044 -9.883  9.019   1.000 13.276 0 50   VAL A HA   1 c 
ATOM   839  H HB   . VAL A 1 55  ? -9.577  -7.099  9.241   1.000 12.873 0 50   VAL A HB   1 c 
ATOM   840  H HG11 . VAL A 1 55  ? -7.671  -9.187  9.521   1.000 13.131 0 50   VAL A HG11 1 c 
ATOM   841  H HG12 . VAL A 1 55  ? -7.966  -8.037  10.575  1.000 13.134 0 50   VAL A HG12 1 c 
ATOM   842  H HG13 . VAL A 1 55  ? -7.226  -7.695  9.214   1.000 13.131 0 50   VAL A HG13 1 c 
ATOM   843  H HG21 . VAL A 1 55  ? -8.407  -7.376  7.177   1.000 13.109 0 50   VAL A HG21 1 c 
ATOM   844  H HG22 . VAL A 1 55  ? -9.954  -7.693  7.034   1.000 13.111 0 50   VAL A HG22 1 c 
ATOM   845  H HG23 . VAL A 1 55  ? -8.907  -8.881  7.130   1.000 13.104 0 50   VAL A HG23 1 c 
ATOM   846  N N    . ASN A 1 56  ? -11.073 -8.191  11.537  1.000 13.374 0 51   ASN A N    1 ? 
ATOM   847  C CA   . ASN A 1 56  ? -11.194 -8.180  12.984  1.000 14.365 0 51   ASN A CA   1 ? 
ATOM   848  C C    . ASN A 1 56  ? -12.599 -7.703  13.362  1.000 12.925 0 51   ASN A C    1 ? 
ATOM   849  O O    . ASN A 1 56  ? -12.873 -6.501  13.399  1.000 13.684 0 51   ASN A O    1 ? 
ATOM   850  C CB   . ASN A 1 56  ? -10.124 -7.297  13.610  1.000 17.232 0 51   ASN A CB   1 ? 
ATOM   851  C CG   . ASN A 1 56  ? -10.127 -7.368  15.112  1.000 19.597 0 51   ASN A CG   1 ? 
ATOM   852  O OD1  . ASN A 1 56  ? -11.041 -7.930  15.722  1.000 21.223 0 51   ASN A OD1  1 ? 
ATOM   853  N ND2  . ASN A 1 56  ? -9.113  -6.791  15.730  1.000 24.564 0 51   ASN A ND2  1 ? 
ATOM   854  H H    . ASN A 1 56  ? -11.446 -7.502  11.067  1.000 13.682 0 51   ASN A H    1 c 
ATOM   855  H HA   . ASN A 1 56  ? -11.064 -9.095  13.321  1.000 14.411 0 51   ASN A HA   1 c 
ATOM   856  H HB2  . ASN A 1 56  ? -9.246  -7.575  13.279  1.000 17.028 0 51   ASN A HB2  1 c 
ATOM   857  H HB3  . ASN A 1 56  ? -10.269 -6.370  13.333  1.000 17.012 0 51   ASN A HB3  1 c 
ATOM   858  H HD21 . ASN A 1 56  ? -8.477  -6.389  15.261  1.000 22.860 0 51   ASN A HD21 1 c 
ATOM   859  H HD22 . ASN A 1 56  ? -9.070  -6.806  16.616  1.000 22.887 0 51   ASN A HD22 1 c 
ATOM   860  N N    . ARG A 1 57  ? -13.459 -8.688  13.706  1.000 13.709 0 52   ARG A N    1 ? 
ATOM   861  C CA   . ARG A 1 57  ? -14.820 -8.380  14.143  1.000 14.540 0 52   ARG A CA   1 ? 
ATOM   862  C C    . ARG A 1 57  ? -14.993 -8.248  15.654  1.000 16.361 0 52   ARG A C    1 ? 
ATOM   863  O O    . ARG A 1 57  ? -16.117 -8.143  16.162  1.000 15.432 0 52   ARG A O    1 ? 
ATOM   864  C CB   . ARG A 1 57  ? -15.742 -9.465  13.578  1.000 13.550 0 52   ARG A CB   1 ? 
ATOM   865  C CG   . ARG A 1 57  ? -15.844 -9.560  12.056  1.000 13.391 0 52   ARG A CG   1 ? 
ATOM   866  C CD   . ARG A 1 57  ? -16.660 -10.721 11.549  1.000 13.635 0 52   ARG A CD   1 ? 
ATOM   867  N NE   . ARG A 1 57  ? -18.080 -10.652 11.936  1.000 14.655 0 52   ARG A NE   1 ? 
ATOM   868  C CZ   . ARG A 1 57  ? -19.053 -10.198 11.177  1.000 13.387 0 52   ARG A CZ   1 ? 
ATOM   869  N NH1  . ARG A 1 57  ? -18.784 -9.521  10.063  1.000 12.600 0 52   ARG A NH1  1 ? 
ATOM   870  N NH2  . ARG A 1 57  ? -20.329 -10.249 11.594  1.000 14.124 0 52   ARG A NH2  1 ? 
ATOM   871  H H    . ARG A 1 57  ? -13.192 -9.561  13.666  1.000 13.706 0 52   ARG A H    1 c 
ATOM   872  H HA   . ARG A 1 57  ? -15.087 -7.520  13.730  1.000 14.487 0 52   ARG A HA   1 c 
ATOM   873  H HB2  . ARG A 1 57  ? -15.436 -10.332 13.920  1.000 13.736 0 52   ARG A HB2  1 c 
ATOM   874  H HB3  . ARG A 1 57  ? -16.644 -9.315  13.935  1.000 13.754 0 52   ARG A HB3  1 c 
ATOM   875  H HG2  . ARG A 1 57  ? -16.237 -8.728  11.713  1.000 13.483 0 52   ARG A HG2  1 c 
ATOM   876  H HG3  . ARG A 1 57  ? -14.938 -9.628  11.682  1.000 13.484 0 52   ARG A HG3  1 c 
ATOM   877  H HD2  . ARG A 1 57  ? -16.593 -10.758 10.574  1.000 13.795 0 52   ARG A HD2  1 c 
ATOM   878  H HD3  . ARG A 1 57  ? -16.275 -11.549 11.902  1.000 13.808 0 52   ARG A HD3  1 c 
ATOM   879  H HE   . ARG A 1 57  ? -18.292 -10.933 12.733  1.000 14.106 0 52   ARG A HE   1 c 
ATOM   880  H HH11 . ARG A 1 57  ? -19.210 -9.722  9.315   1.000 12.838 0 52   ARG A HH11 1 c 
ATOM   881  H HH12 . ARG A 1 57  ? -18.182 -8.872  10.076  1.000 12.842 0 52   ARG A HH12 1 c 
ATOM   882  H HH21 . ARG A 1 57  ? -20.977 -9.977  11.058  1.000 13.869 0 52   ARG A HH21 1 c 
ATOM   883  H HH22 . ARG A 1 57  ? -20.518 -10.555 12.402  1.000 13.895 0 52   ARG A HH22 1 c 
ATOM   884  N N    . VAL A 1 58  ? -13.890 -8.098  16.403  1.000 16.185 0 53   VAL A N    1 ? 
ATOM   885  C CA   . VAL A 1 58  ? -14.011 -7.957  17.848  1.000 19.197 0 53   VAL A CA   1 ? 
ATOM   886  C C    . VAL A 1 58  ? -14.750 -6.674  18.175  1.000 17.730 0 53   VAL A C    1 ? 
ATOM   887  O O    . VAL A 1 58  ? -14.425 -5.570  17.736  1.000 21.482 0 53   VAL A O    1 ? 
ATOM   888  C CB   . VAL A 1 58  ? -12.641 -8.033  18.561  1.000 20.619 0 53   VAL A CB   1 ? 
ATOM   889  C CG1  . VAL A 1 58  ? -12.751 -7.706  20.051  1.000 25.485 0 53   VAL A CG1  1 ? 
ATOM   890  C CG2  . VAL A 1 58  ? -12.075 -9.417  18.378  1.000 22.595 0 53   VAL A CG2  1 ? 
ATOM   891  H H    . VAL A 1 58  ? -13.062 -8.079  16.018  1.000 16.875 0 53   VAL A H    1 c 
ATOM   892  H HA   . VAL A 1 58  ? -14.551 -8.705  18.170  1.000 18.552 0 53   VAL A HA   1 c 
ATOM   893  H HB   . VAL A 1 58  ? -12.040 -7.380  18.132  1.000 21.526 0 53   VAL A HB   1 c 
ATOM   894  H HG11 . VAL A 1 58  ? -13.490 -8.205  20.439  1.000 23.931 0 53   VAL A HG11 1 c 
ATOM   895  H HG12 . VAL A 1 58  ? -12.909 -6.754  20.166  1.000 23.902 0 53   VAL A HG12 1 c 
ATOM   896  H HG13 . VAL A 1 58  ? -11.924 -7.952  20.499  1.000 23.914 0 53   VAL A HG13 1 c 
ATOM   897  H HG21 . VAL A 1 58  ? -11.200 -9.469  18.798  1.000 21.980 0 53   VAL A HG21 1 c 
ATOM   898  H HG22 . VAL A 1 58  ? -11.989 -9.613  17.430  1.000 21.908 0 53   VAL A HG22 1 c 
ATOM   899  H HG23 . VAL A 1 58  ? -12.669 -10.068 18.788  1.000 21.970 0 53   VAL A HG23 1 c 
ATOM   900  N N    . GLY A 1 59  ? -15.804 -6.837  18.994  1.000 20.706 0 74   GLY A N    1 ? 
ATOM   901  C CA   . GLY A 1 59  ? -16.545 -5.671  19.425  1.000 21.668 0 74   GLY A CA   1 ? 
ATOM   902  C C    . GLY A 1 59  ? -17.666 -5.249  18.462  1.000 18.599 0 74   GLY A C    1 ? 
ATOM   903  O O    . GLY A 1 59  ? -18.316 -4.231  18.736  1.000 20.548 0 74   GLY A O    1 ? 
ATOM   904  H H    . GLY A 1 59  ? -16.056 -7.667  19.281  1.000 20.135 0 74   GLY A H    1 c 
ATOM   905  H HA2  . GLY A 1 59  ? -16.940 -5.862  20.308  1.000 20.716 0 74   GLY A HA2  1 c 
ATOM   906  H HA3  . GLY A 1 59  ? -15.918 -4.919  19.540  1.000 20.706 0 74   GLY A HA3  1 c 
ATOM   907  N N    . LEU A 1 60  ? -17.765 -5.891  17.276  1.000 17.663 0 75   LEU A N    1 ? 
ATOM   908  C CA   . LEU A 1 60  ? -18.774 -5.484  16.303  1.000 15.521 0 75   LEU A CA   1 ? 
ATOM   909  C C    . LEU A 1 60  ? -20.171 -5.693  16.910  1.000 13.761 0 75   LEU A C    1 ? 
ATOM   910  O O    . LEU A 1 60  ? -20.446 -6.786  17.397  1.000 14.933 0 75   LEU A O    1 ? 
ATOM   911  C CB   . LEU A 1 60  ? -18.590 -6.361  15.073  1.000 13.787 0 75   LEU A CB   1 ? 
ATOM   912  C CG   . LEU A 1 60  ? -19.620 -6.112  13.952  1.000 14.492 0 75   LEU A CG   1 ? 
ATOM   913  C CD1  . LEU A 1 60  ? -19.445 -4.782  13.296  1.000 14.465 0 75   LEU A CD1  1 ? 
ATOM   914  C CD2  . LEU A 1 60  ? -19.496 -7.245  12.951  1.000 15.274 0 75   LEU A CD2  1 ? 
ATOM   915  H H    . LEU A 1 60  ? -17.208 -6.588  17.078  1.000 17.342 0 75   LEU A H    1 c 
ATOM   916  H HA   . LEU A 1 60  ? -18.640 -4.532  16.069  1.000 15.280 0 75   LEU A HA   1 c 
ATOM   917  H HB2  . LEU A 1 60  ? -17.688 -6.203  14.712  1.000 14.340 0 75   LEU A HB2  1 c 
ATOM   918  H HB3  . LEU A 1 60  ? -18.651 -7.303  15.353  1.000 14.356 0 75   LEU A HB3  1 c 
ATOM   919  H HG   . LEU A 1 60  ? -20.529 -6.148  14.346  1.000 14.494 0 75   LEU A HG   1 c 
ATOM   920  H HD11 . LEU A 1 60  ? -19.575 -4.076  13.951  1.000 14.494 0 75   LEU A HD11 1 c 
ATOM   921  H HD12 . LEU A 1 60  ? -20.098 -4.684  12.582  1.000 14.478 0 75   LEU A HD12 1 c 
ATOM   922  H HD13 . LEU A 1 60  ? -18.549 -4.717  12.925  1.000 14.478 0 75   LEU A HD13 1 c 
ATOM   923  H HD21 . LEU A 1 60  ? -19.703 -8.088  13.386  1.000 15.034 0 75   LEU A HD21 1 c 
ATOM   924  H HD22 . LEU A 1 60  ? -18.588 -7.274  12.604  1.000 15.037 0 75   LEU A HD22 1 c 
ATOM   925  H HD23 . LEU A 1 60  ? -20.117 -7.099  12.217  1.000 15.037 0 75   LEU A HD23 1 c 
ATOM   926  N N    . THR A 1 61  ? -21.047 -4.716  16.753  1.000 12.225 0 76   THR A N    1 ? 
ATOM   927  C CA   . THR A 1 61  ? -22.441 -4.887  17.189  1.000 12.812 0 76   THR A CA   1 ? 
ATOM   928  C C    . THR A 1 61  ? -23.420 -4.661  16.051  1.000 13.591 0 76   THR A C    1 ? 
ATOM   929  O O    . THR A 1 61  ? -24.572 -5.132  16.129  1.000 14.579 0 76   THR A O    1 ? 
ATOM   930  C CB   . THR A 1 61  ? -22.736 -3.984  18.378  1.000 14.257 0 76   THR A CB   1 ? 
ATOM   931  O OG1  . THR A 1 61  ? -22.552 -2.622  18.009  1.000 16.228 0 76   THR A OG1  1 ? 
ATOM   932  C CG2  . THR A 1 61  ? -21.956 -4.397  19.606  1.000 15.893 0 76   THR A CG2  1 ? 
ATOM   933  H H    . THR A 1 61  ? -20.783 -3.916  16.398  1.000 12.743 0 76   THR A H    1 c 
ATOM   934  H HA   . THR A 1 61  ? -22.547 -5.815  17.492  1.000 13.109 0 76   THR A HA   1 c 
ATOM   935  H HB   . THR A 1 61  ? -23.688 -4.108  18.606  1.000 14.623 0 76   THR A HB   1 c 
ATOM   936  H HG1  . THR A 1 61  ? -21.736 -2.499  17.754  0.000 16.240 0 76   THR A HG1  1 c 
ATOM   937  H HG21 . THR A 1 61  ? -22.180 -3.813  20.348  1.000 15.385 0 76   THR A HG21 1 c 
ATOM   938  H HG22 . THR A 1 61  ? -21.003 -4.333  19.423  1.000 15.370 0 76   THR A HG22 1 c 
ATOM   939  H HG23 . THR A 1 61  ? -22.178 -5.314  19.839  1.000 15.385 0 76   THR A HG23 1 c 
ATOM   940  N N    . TYR A 1 62  ? -22.996 -3.933  14.986  1.000 12.532 0 77   TYR A N    1 ? 
ATOM   941  C CA   . TYR A 1 62  ? -23.887 -3.711  13.838  1.000 12.057 0 77   TYR A CA   1 ? 
ATOM   942  C C    . TYR A 1 62  ? -23.000 -3.359  12.632  1.000 11.633 0 77   TYR A C    1 ? 
ATOM   943  O O    . TYR A 1 62  ? -23.006 -4.076  11.633  1.000 12.798 0 77   TYR A O    1 ? 
ATOM   944  C CB   . TYR A 1 62  ? -24.988 -2.683  14.114  1.000 12.757 0 77   TYR A CB   1 ? 
ATOM   945  C CG   . TYR A 1 62  ? -25.843 -2.364  12.889  1.000 13.414 0 77   TYR A CG   1 ? 
ATOM   946  C CD1  . TYR A 1 62  ? -25.778 -1.113  12.281  1.000 14.222 0 77   TYR A CD1  1 ? 
ATOM   947  C CD2  . TYR A 1 62  ? -26.595 -3.335  12.281  1.000 14.877 0 77   TYR A CD2  1 ? 
ATOM   948  C CE1  . TYR A 1 62  ? -26.501 -0.854  11.128  1.000 15.085 0 77   TYR A CE1  1 ? 
ATOM   949  C CE2  . TYR A 1 62  ? -27.297 -3.094  11.116  1.000 15.988 0 77   TYR A CE2  1 ? 
ATOM   950  C CZ   . TYR A 1 62  ? -27.260 -1.836  10.555  1.000 16.893 0 77   TYR A CZ   1 ? 
ATOM   951  O OH   . TYR A 1 62  ? -27.911 -1.487  9.380   1.000 18.705 0 77   TYR A OH   1 ? 
ATOM   952  H H    . TYR A 1 62  ? -22.159 -3.568  14.979  1.000 12.646 0 77   TYR A H    1 c 
ATOM   953  H HA   . TYR A 1 62  ? -24.333 -4.576  13.636  1.000 12.217 0 77   TYR A HA   1 c 
ATOM   954  H HB2  . TYR A 1 62  ? -25.569 -3.029  14.827  1.000 12.755 0 77   TYR A HB2  1 c 
ATOM   955  H HB3  . TYR A 1 62  ? -24.570 -1.855  14.437  1.000 12.777 0 77   TYR A HB3  1 c 
ATOM   956  H HD1  . TYR A 1 62  ? -25.253 -0.430  12.668  1.000 14.243 0 77   TYR A HD1  1 c 
ATOM   957  H HD2  . TYR A 1 62  ? -26.618 -4.200  12.658  1.000 14.774 0 77   TYR A HD2  1 c 
ATOM   958  H HE1  . TYR A 1 62  ? -26.462 -0.001  10.731  1.000 15.285 0 77   TYR A HE1  1 c 
ATOM   959  H HE2  . TYR A 1 62  ? -27.823 -3.772  10.728  1.000 15.899 0 77   TYR A HE2  1 c 
ATOM   960  H HH   . TYR A 1 62  ? -27.411 -1.659  8.705   0.000 18.700 0 77   TYR A HH   1 c 
ATOM   961  N N    . PHE A 1 63  ? -22.331 -2.211  12.727  1.000 11.684 0 78   PHE A N    1 ? 
ATOM   962  C CA   . PHE A 1 63  ? -21.556 -1.686  11.614  1.000 11.723 0 78   PHE A CA   1 ? 
ATOM   963  C C    . PHE A 1 63  ? -20.426 -0.889  12.225  1.000 11.565 0 78   PHE A C    1 ? 
ATOM   964  O O    . PHE A 1 63  ? -20.625 -0.097  13.149  1.000 12.723 0 78   PHE A O    1 ? 
ATOM   965  C CB   . PHE A 1 63  ? -22.440 -0.838  10.685  1.000 12.424 0 78   PHE A CB   1 ? 
ATOM   966  C CG   . PHE A 1 63  ? -21.699 -0.401  9.428   1.000 13.056 0 78   PHE A CG   1 ? 
ATOM   967  C CD1  . PHE A 1 63  ? -21.672 -1.222  8.318   1.000 14.761 0 78   PHE A CD1  1 ? 
ATOM   968  C CD2  . PHE A 1 63  ? -21.028 0.798   9.410   1.000 15.149 0 78   PHE A CD2  1 ? 
ATOM   969  C CE1  . PHE A 1 63  ? -20.962 -0.854  7.185   1.000 14.057 0 78   PHE A CE1  1 ? 
ATOM   970  C CE2  . PHE A 1 63  ? -20.364 1.172   8.247   1.000 14.984 0 78   PHE A CE2  1 ? 
ATOM   971  C CZ   . PHE A 1 63  ? -20.347 0.357   7.183   1.000 14.355 0 78   PHE A CZ   1 ? 
ATOM   972  H H    . PHE A 1 63  ? -22.361 -1.736  13.508  1.000 11.707 0 78   PHE A H    1 c 
ATOM   973  H HA   . PHE A 1 63  ? -21.179 -2.446  11.098  1.000 11.807 0 78   PHE A HA   1 c 
ATOM   974  H HB2  . PHE A 1 63  ? -23.229 -1.366  10.428  1.000 12.404 0 78   PHE A HB2  1 c 
ATOM   975  H HB3  . PHE A 1 63  ? -22.743 -0.041  11.175  1.000 12.415 0 78   PHE A HB3  1 c 
ATOM   976  H HD1  . PHE A 1 63  ? -22.111 -2.058  8.346   1.000 14.183 0 78   PHE A HD1  1 c 
ATOM   977  H HD2  . PHE A 1 63  ? -21.053 1.373   10.158  1.000 14.579 0 78   PHE A HD2  1 c 
ATOM   978  H HE1  . PHE A 1 63  ? -20.955 -1.405  6.418   1.000 14.284 0 78   PHE A HE1  1 c 
ATOM   979  H HE2  . PHE A 1 63  ? -19.905 1.996   8.214   1.000 14.844 0 78   PHE A HE2  1 c 
ATOM   980  H HZ   . PHE A 1 63  ? -19.875 0.626   6.411   1.000 14.427 0 78   PHE A HZ   1 c 
ATOM   981  N N    . PRO A 1 64  ? -19.198 -0.990  11.654  1.000 10.760 0 79   PRO A N    1 ? 
ATOM   982  C CA   . PRO A 1 64  ? -18.072 -0.202  12.167  1.000 11.250 0 79   PRO A CA   1 ? 
ATOM   983  C C    . PRO A 1 64  ? -18.196 1.249   11.748  1.000 11.789 0 79   PRO A C    1 ? 
ATOM   984  O O    . PRO A 1 64  ? -17.946 1.593   10.596  1.000 12.481 0 79   PRO A O    1 ? 
ATOM   985  C CB   . PRO A 1 64  ? -16.833 -0.881  11.540  1.000 12.103 0 79   PRO A CB   1 ? 
ATOM   986  C CG   . PRO A 1 64  ? -17.379 -1.428  10.252  1.000 12.791 0 79   PRO A CG   1 ? 
ATOM   987  C CD   . PRO A 1 64  ? -18.793 -1.896  10.585  1.000 11.769 0 79   PRO A CD   1 ? 
ATOM   988  H HA   . PRO A 1 64  ? -18.033 -0.276  13.153  1.000 11.409 0 79   PRO A HA   1 c 
ATOM   989  H HB2  . PRO A 1 64  ? -16.113 -0.227  11.374  1.000 12.058 0 79   PRO A HB2  1 c 
ATOM   990  H HB3  . PRO A 1 64  ? -16.494 -1.603  12.118  1.000 12.043 0 79   PRO A HB3  1 c 
ATOM   991  H HG2  . PRO A 1 64  ? -17.397 -0.735  9.559   1.000 12.397 0 79   PRO A HG2  1 c 
ATOM   992  H HG3  . PRO A 1 64  ? -16.833 -2.177  9.934   1.000 12.397 0 79   PRO A HG3  1 c 
ATOM   993  H HD2  . PRO A 1 64  ? -19.382 -1.813  9.804   1.000 11.758 0 79   PRO A HD2  1 c 
ATOM   994  H HD3  . PRO A 1 64  ? -18.793 -2.829  10.893  1.000 11.742 0 79   PRO A HD3  1 c 
ATOM   995  N N    . VAL A 1 65  ? -18.596 2.122   12.663  1.000 11.744 0 80   VAL A N    1 ? 
ATOM   996  C CA   . VAL A 1 65  ? -18.815 3.512   12.333  1.000 11.705 0 80   VAL A CA   1 ? 
ATOM   997  C C    . VAL A 1 65  ? -17.503 4.115   11.831  1.000 11.737 0 80   VAL A C    1 ? 
ATOM   998  O O    . VAL A 1 65  ? -16.472 4.028   12.482  1.000 11.817 0 80   VAL A O    1 ? 
ATOM   999  C CB   . VAL A 1 65  ? -19.370 4.282   13.549  1.000 14.397 0 80   VAL A CB   1 ? 
ATOM   1000 C CG1  . VAL A 1 65  ? -19.465 5.790   13.298  1.000 14.938 0 80   VAL A CG1  1 ? 
ATOM   1001 C CG2  . VAL A 1 65  ? -20.708 3.676   13.995  1.000 15.174 0 80   VAL A CG2  1 ? 
ATOM   1002 H H    . VAL A 1 65  ? -18.725 1.844   13.524  1.000 11.797 0 80   VAL A H    1 c 
ATOM   1003 H HA   . VAL A 1 65  ? -19.474 3.553   11.615  1.000 12.171 0 80   VAL A HA   1 c 
ATOM   1004 H HB   . VAL A 1 65  ? -18.729 4.150   14.287  1.000 14.085 0 80   VAL A HB   1 c 
ATOM   1005 H HG11 . VAL A 1 65  ? -19.918 5.950   12.453  1.000 14.773 0 80   VAL A HG11 1 c 
ATOM   1006 H HG12 . VAL A 1 65  ? -18.572 6.173   13.264  1.000 14.759 0 80   VAL A HG12 1 c 
ATOM   1007 H HG13 . VAL A 1 65  ? -19.968 6.208   14.018  1.000 14.774 0 80   VAL A HG13 1 c 
ATOM   1008 H HG21 . VAL A 1 65  ? -21.108 4.241   14.678  1.000 14.930 0 80   VAL A HG21 1 c 
ATOM   1009 H HG22 . VAL A 1 65  ? -20.560 2.788   14.358  1.000 14.895 0 80   VAL A HG22 1 c 
ATOM   1010 H HG23 . VAL A 1 65  ? -21.308 3.618   13.232  1.000 14.931 0 80   VAL A HG23 1 c 
ATOM   1011 N N    . ALA A 1 66  ? -17.597 4.779   10.688  1.000 11.926 0 81   ALA A N    1 ? 
ATOM   1012 C CA   . ALA A 1 66  ? -16.457 5.473   10.100  1.000 11.504 0 81   ALA A CA   1 ? 
ATOM   1013 C C    . ALA A 1 66  ? -16.585 6.962   10.402  1.000 11.893 0 81   ALA A C    1 ? 
ATOM   1014 O O    . ALA A 1 66  ? -17.394 7.682   9.808   1.000 12.856 0 81   ALA A O    1 ? 
ATOM   1015 C CB   . ALA A 1 66  ? -16.326 5.217   8.618   1.000 11.314 0 81   ALA A CB   1 ? 
ATOM   1016 H H    . ALA A 1 66  ? -18.399 4.807   10.250  1.000 11.787 0 81   ALA A H    1 c 
ATOM   1017 H HA   . ALA A 1 66  ? -15.631 5.140   10.547  1.000 11.624 0 81   ALA A HA   1 c 
ATOM   1018 H HB1  . ALA A 1 66  ? -16.212 4.265   8.459   1.000 11.372 0 81   ALA A HB1  1 c 
ATOM   1019 H HB2  . ALA A 1 66  ? -17.126 5.525   8.160   1.000 11.377 0 81   ALA A HB2  1 c 
ATOM   1020 H HB3  . ALA A 1 66  ? -15.554 5.695   8.271   1.000 11.372 0 81   ALA A HB3  1 c 
ATOM   1021 N N    . ASP A 1 67  ? -15.821 7.388   11.420  1.000 11.694 0 82   ASP A N    1 ? 
ATOM   1022 C CA   . ASP A 1 67  ? -15.793 8.783   11.803  1.000 12.169 0 82   ASP A CA   1 ? 
ATOM   1023 C C    . ASP A 1 67  ? -14.922 9.592   10.861  1.000 13.147 0 82   ASP A C    1 ? 
ATOM   1024 O O    . ASP A 1 67  ? -13.877 9.105   10.424  1.000 12.956 0 82   ASP A O    1 ? 
ATOM   1025 C CB   . ASP A 1 67  ? -15.274 8.942   13.221  1.000 14.669 0 82   ASP A CB   1 ? 
ATOM   1026 C CG   . ASP A 1 67  ? -16.181 8.276   14.235  1.000 17.840 0 82   ASP A CG   1 ? 
ATOM   1027 O OD1  . ASP A 1 67  ? -17.323 8.726   14.340  1.000 20.529 0 82   ASP A OD1  1 ? 
ATOM   1028 O OD2  . ASP A 1 67  ? -15.730 7.351   14.900  1.000 20.704 0 82   ASP A OD2  1 ? 
ATOM   1029 H H    . ASP A 1 67  ? -15.306 6.791   11.883  1.000 11.885 0 82   ASP A H    1 c 
ATOM   1030 H HA   . ASP A 1 67  ? -16.711 9.134   11.769  1.000 12.717 0 82   ASP A HA   1 c 
ATOM   1031 H HB2  . ASP A 1 67  ? -14.380 8.546   13.287  1.000 14.736 0 82   ASP A HB2  1 c 
ATOM   1032 H HB3  . ASP A 1 67  ? -15.207 9.895   13.439  1.000 14.704 0 82   ASP A HB3  1 c 
ATOM   1033 N N    . LEU A 1 68  ? -15.303 10.846  10.616  1.000 13.750 0 83   LEU A N    1 ? 
ATOM   1034 C CA   . LEU A 1 68  ? -14.510 11.700  9.759   1.000 13.421 0 83   LEU A CA   1 ? 
ATOM   1035 C C    . LEU A 1 68  ? -13.086 11.852  10.293  1.000 14.488 0 83   LEU A C    1 ? 
ATOM   1036 O O    . LEU A 1 68  ? -12.136 11.865  9.524   1.000 14.279 0 83   LEU A O    1 ? 
ATOM   1037 C CB   . LEU A 1 68  ? -15.177 13.063  9.598   1.000 16.478 0 83   LEU A CB   1 ? 
ATOM   1038 C CG   . LEU A 1 68  ? -14.385 14.071  8.783   1.000 18.729 0 83   LEU A CG   1 ? 
ATOM   1039 C CD1  . LEU A 1 68  ? -14.216 13.562  7.375   1.000 18.464 0 83   LEU A CD1  1 ? 
ATOM   1040 C CD2  . LEU A 1 68  ? -15.110 15.420  8.884   1.000 21.460 0 83   LEU A CD2  1 ? 
ATOM   1041 H H    . LEU A 1 68  ? -16.070 11.175  10.990  1.000 13.531 0 83   LEU A H    1 c 
ATOM   1042 H HA   . LEU A 1 68  ? -14.457 11.265  8.871   1.000 14.235 0 83   LEU A HA   1 c 
ATOM   1043 H HB2  . LEU A 1 68  ? -16.052 12.930  9.167   1.000 16.194 0 83   LEU A HB2  1 c 
ATOM   1044 H HB3  . LEU A 1 68  ? -15.333 13.438  10.496  1.000 16.240 0 83   LEU A HB3  1 c 
ATOM   1045 H HG   . LEU A 1 68  ? -13.487 14.170  9.190   1.000 18.737 0 83   LEU A HG   1 c 
ATOM   1046 H HD11 . LEU A 1 68  ? -13.594 12.815  7.370   1.000 18.470 0 83   LEU A HD11 1 c 
ATOM   1047 H HD12 . LEU A 1 68  ? -13.866 14.274  6.813   1.000 18.520 0 83   LEU A HD12 1 c 
ATOM   1048 H HD13 . LEU A 1 68  ? -15.076 13.270  7.028   1.000 18.498 0 83   LEU A HD13 1 c 
ATOM   1049 H HD21 . LEU A 1 68  ? -15.209 15.666  9.818   1.000 20.585 0 83   LEU A HD21 1 c 
ATOM   1050 H HD22 . LEU A 1 68  ? -15.988 15.348  8.473   1.000 20.611 0 83   LEU A HD22 1 c 
ATOM   1051 H HD23 . LEU A 1 68  ? -14.593 16.102  8.424   1.000 20.605 0 83   LEU A HD23 1 c 
ATOM   1052 N N    . SER A 1 69  ? -12.902 11.986  11.606  1.000 14.127 0 84   SER A N    1 ? 
ATOM   1053 C CA   . SER A 1 69  ? -11.564 12.209  12.134  1.000 14.738 0 84   SER A CA   1 ? 
ATOM   1054 C C    . SER A 1 69  ? -10.614 11.076  11.761  1.000 14.421 0 84   SER A C    1 ? 
ATOM   1055 O O    . SER A 1 69  ? -9.455  11.324  11.357  1.000 15.430 0 84   SER A O    1 ? 
ATOM   1056 C CB   . SER A 1 69  ? -11.590 12.465  13.634  1.000 15.544 0 84   SER A CB   1 ? 
ATOM   1057 O OG   . SER A 1 69  ? -12.083 11.311  14.282  1.000 19.376 0 84   SER A OG   1 ? 
ATOM   1058 H H    . SER A 1 69  ? -13.611 11.943  12.181  1.000 14.345 0 84   SER A H    1 c 
ATOM   1059 H HA   . SER A 1 69  ? -11.217 13.032  11.703  1.000 14.700 0 84   SER A HA   1 c 
ATOM   1060 H HB2  . SER A 1 69  ? -10.689 12.663  13.950  1.000 16.193 0 84   SER A HB2  1 c 
ATOM   1061 H HB3  . SER A 1 69  ? -12.168 13.227  13.829  1.000 16.193 0 84   SER A HB3  1 c 
ATOM   1062 H HG   . SER A 1 69  ? -12.099 11.455  15.114  0.000 19.360 0 84   SER A HG   1 c 
ATOM   1063 N N    . ILE A 1 70  ? -11.133 9.855   11.816  1.000 13.228 0 85   ILE A N    1 ? 
ATOM   1064 C CA   . ILE A 1 70  ? -10.376 8.656   11.517  1.000 13.493 0 85   ILE A CA   1 ? 
ATOM   1065 C C    . ILE A 1 70  ? -10.035 8.581   10.026  1.000 11.549 0 85   ILE A C    1 ? 
ATOM   1066 O O    . ILE A 1 70  ? -8.896  8.347   9.614   1.000 12.337 0 85   ILE A O    1 ? 
ATOM   1067 C CB   . ILE A 1 70  ? -11.175 7.427   11.966  1.000 15.794 0 85   ILE A CB   1 ? 
ATOM   1068 C CG1  . ILE A 1 70  ? -11.360 7.369   13.490  1.000 18.513 0 85   ILE A CG1  1 ? 
ATOM   1069 C CG2  . ILE A 1 70  ? -10.591 6.140   11.424  1.000 16.774 0 85   ILE A CG2  1 ? 
ATOM   1070 C CD1  . ILE A 1 70  ? -10.085 7.285   14.313  1.000 20.100 0 85   ILE A CD1  1 ? 
ATOM   1071 H H    . ILE A 1 70  ? -12.009 9.763   12.058  1.000 13.663 0 85   ILE A H    1 c 
ATOM   1072 H HA   . ILE A 1 70  ? -9.542  8.685   12.023  1.000 13.511 0 85   ILE A HA   1 c 
ATOM   1073 H HB   . ILE A 1 70  ? -12.069 7.516   11.579  1.000 15.945 0 85   ILE A HB   1 c 
ATOM   1074 H HG12 . ILE A 1 70  ? -11.854 8.166   13.771  1.000 18.131 0 85   ILE A HG12 1 c 
ATOM   1075 H HG13 . ILE A 1 70  ? -11.914 6.591   13.702  1.000 18.174 0 85   ILE A HG13 1 c 
ATOM   1076 H HG21 . ILE A 1 70  ? -10.965 5.384   11.908  1.000 16.486 0 85   ILE A HG21 1 c 
ATOM   1077 H HG22 . ILE A 1 70  ? -9.625  6.147   11.536  1.000 16.448 0 85   ILE A HG22 1 c 
ATOM   1078 H HG23 . ILE A 1 70  ? -10.806 6.054   10.480  1.000 16.444 0 85   ILE A HG23 1 c 
ATOM   1079 H HD11 . ILE A 1 70  ? -9.545  6.531   14.007  1.000 19.602 0 85   ILE A HD11 1 c 
ATOM   1080 H HD12 . ILE A 1 70  ? -10.315 7.157   15.253  1.000 19.613 0 85   ILE A HD12 1 c 
ATOM   1081 H HD13 . ILE A 1 70  ? -9.573  8.110   14.215  1.000 19.608 0 85   ILE A HD13 1 c 
ATOM   1082 N N    . ILE A 1 71  ? -11.043 8.771   9.173   1.000 10.697 0 86   ILE A N    1 ? 
ATOM   1083 C CA   . ILE A 1 71  ? -10.837 8.657   7.737   1.000 10.585 0 86   ILE A CA   1 ? 
ATOM   1084 C C    . ILE A 1 71  ? -9.951  9.794   7.251   1.000 10.713 0 86   ILE A C    1 ? 
ATOM   1085 O O    . ILE A 1 71  ? -9.097  9.589   6.397   1.000 11.007 0 86   ILE A O    1 ? 
ATOM   1086 C CB   . ILE A 1 71  ? -12.177 8.599   6.991   1.000 10.687 0 86   ILE A CB   1 ? 
ATOM   1087 C CG1  . ILE A 1 71  ? -12.986 7.377   7.395   1.000 11.606 0 86   ILE A CG1  1 ? 
ATOM   1088 C CG2  . ILE A 1 71  ? -12.004 8.696   5.491   1.000 11.836 0 86   ILE A CG2  1 ? 
ATOM   1089 C CD1  . ILE A 1 71  ? -12.345 6.030   7.116   1.000 11.974 0 86   ILE A CD1  1 ? 
ATOM   1090 H H    . ILE A 1 71  ? -11.875 8.978   9.489   1.000 10.906 0 86   ILE A H    1 c 
ATOM   1091 H HA   . ILE A 1 71  ? -10.365 7.819   7.569   1.000 10.676 0 86   ILE A HA   1 c 
ATOM   1092 H HB   . ILE A 1 71  ? -12.691 9.382   7.271   1.000 11.046 0 86   ILE A HB   1 c 
ATOM   1093 H HG12 . ILE A 1 71  ? -13.176 7.435   8.353   1.000 11.465 0 86   ILE A HG12 1 c 
ATOM   1094 H HG13 . ILE A 1 71  ? -13.845 7.410   6.925   1.000 11.481 0 86   ILE A HG13 1 c 
ATOM   1095 H HG21 . ILE A 1 71  ? -12.836 8.455   5.050   1.000 11.483 0 86   ILE A HG21 1 c 
ATOM   1096 H HG22 . ILE A 1 71  ? -11.300 8.090   5.204   1.000 11.483 0 86   ILE A HG22 1 c 
ATOM   1097 H HG23 . ILE A 1 71  ? -11.765 9.607   5.247   1.000 11.480 0 86   ILE A HG23 1 c 
ATOM   1098 H HD11 . ILE A 1 71  ? -12.065 5.985   6.182   1.000 11.860 0 86   ILE A HD11 1 c 
ATOM   1099 H HD12 . ILE A 1 71  ? -12.993 5.322   7.293   1.000 11.860 0 86   ILE A HD12 1 c 
ATOM   1100 H HD13 . ILE A 1 71  ? -11.567 5.907   7.693   1.000 11.848 0 86   ILE A HD13 1 c 
ATOM   1101 N N    . ALA A 1 72  ? -10.202 11.022  7.729   1.000 11.108 0 87   ALA A N    1 ? 
ATOM   1102 C CA   . ALA A 1 72  ? -9.399  12.168  7.344   1.000 11.832 0 87   ALA A CA   1 ? 
ATOM   1103 C C    . ALA A 1 72  ? -7.948  11.967  7.759   1.000 11.593 0 87   ALA A C    1 ? 
ATOM   1104 O O    . ALA A 1 72  ? -7.056  12.381  7.007   1.000 11.947 0 87   ALA A O    1 ? 
ATOM   1105 C CB   . ALA A 1 72  ? -9.972  13.459  7.906   1.000 13.314 0 87   ALA A CB   1 ? 
ATOM   1106 H H    . ALA A 1 72  ? -10.899 11.146  8.308   1.000 11.177 0 87   ALA A H    1 c 
ATOM   1107 H HA   . ALA A 1 72  ? -9.420  12.226  6.349   1.000 11.888 0 87   ALA A HA   1 c 
ATOM   1108 H HB1  . ALA A 1 72  ? -10.875 13.590  7.570   1.000 12.860 0 87   ALA A HB1  1 c 
ATOM   1109 H HB2  . ALA A 1 72  ? -9.994  13.412  8.877   1.000 12.865 0 87   ALA A HB2  1 c 
ATOM   1110 H HB3  . ALA A 1 72  ? -9.417  14.209  7.634   1.000 12.860 0 87   ALA A HB3  1 c 
ATOM   1111 N N    . ALA A 1 73  ? -7.645  11.329  8.901   1.000 12.223 0 88   ALA A N    1 ? 
ATOM   1112 C CA   . ALA A 1 73  ? -6.253  11.143  9.290   1.000 12.507 0 88   ALA A CA   1 ? 
ATOM   1113 C C    . ALA A 1 73  ? -5.592  10.118  8.354   1.000 12.512 0 88   ALA A C    1 ? 
ATOM   1114 O O    . ALA A 1 73  ? -4.439  10.280  8.005   1.000 13.007 0 88   ALA A O    1 ? 
ATOM   1115 C CB   . ALA A 1 73  ? -6.165  10.724  10.761  1.000 13.143 0 88   ALA A CB   1 ? 
ATOM   1116 H H    . ALA A 1 73  ? -8.308  11.011  9.443   1.000 12.131 0 88   ALA A H    1 c 
ATOM   1117 H HA   . ALA A 1 73  ? -5.781  12.014  9.176   1.000 12.555 0 88   ALA A HA   1 c 
ATOM   1118 H HB1  . ALA A 1 73  ? -6.560  11.412  11.322  1.000 12.954 0 88   ALA A HB1  1 c 
ATOM   1119 H HB2  . ALA A 1 73  ? -6.644  9.888   10.892  1.000 12.954 0 88   ALA A HB2  1 c 
ATOM   1120 H HB3  . ALA A 1 73  ? -5.233  10.602  11.011  1.000 12.954 0 88   ALA A HB3  1 c 
ATOM   1121 N N    . LEU A 1 74  ? -6.309  9.051   7.971   1.000 12.464 0 89   LEU A N    1 ? 
ATOM   1122 C CA   . LEU A 1 74  ? -5.759  8.093   7.001   1.000 12.687 0 89   LEU A CA   1 ? 
ATOM   1123 C C    . LEU A 1 74  ? -5.482  8.777   5.661   1.000 11.266 0 89   LEU A C    1 ? 
ATOM   1124 O O    . LEU A 1 74  ? -4.451  8.522   5.022   1.000 11.970 0 89   LEU A O    1 ? 
ATOM   1125 C CB   . LEU A 1 74  ? -6.732  6.947   6.793   1.000 12.327 0 89   LEU A CB   1 ? 
ATOM   1126 C CG   . LEU A 1 74  ? -6.899  5.946   7.950   1.000 13.742 0 89   LEU A CG   1 ? 
ATOM   1127 C CD1  . LEU A 1 74  ? -8.178  5.148   7.811   1.000 14.642 0 89   LEU A CD1  1 ? 
ATOM   1128 C CD2  . LEU A 1 74  ? -5.719  4.989   8.019   1.000 15.712 0 89   LEU A CD2  1 ? 
ATOM   1129 H H    . LEU A 1 74  ? -7.143  8.909   8.318   1.000 12.522 0 89   LEU A H    1 c 
ATOM   1130 H HA   . LEU A 1 74  ? -4.907  7.737   7.360   1.000 12.326 0 89   LEU A HA   1 c 
ATOM   1131 H HB2  . LEU A 1 74  ? -7.616  7.332   6.590   1.000 12.724 0 89   LEU A HB2  1 c 
ATOM   1132 H HB3  . LEU A 1 74  ? -6.448  6.447   5.994   1.000 12.710 0 89   LEU A HB3  1 c 
ATOM   1133 H HG   . LEU A 1 74  ? -6.939  6.455   8.800   1.000 13.976 0 89   LEU A HG   1 c 
ATOM   1134 H HD11 . LEU A 1 74  ? -8.940  5.752   7.815   1.000 14.357 0 89   LEU A HD11 1 c 
ATOM   1135 H HD12 . LEU A 1 74  ? -8.256  4.525   8.554   1.000 14.366 0 89   LEU A HD12 1 c 
ATOM   1136 H HD13 . LEU A 1 74  ? -8.163  4.652   6.975   1.000 14.366 0 89   LEU A HD13 1 c 
ATOM   1137 H HD21 . LEU A 1 74  ? -4.900  5.492   8.167   1.000 15.081 0 89   LEU A HD21 1 c 
ATOM   1138 H HD22 . LEU A 1 74  ? -5.649  4.498   7.184   1.000 15.097 0 89   LEU A HD22 1 c 
ATOM   1139 H HD23 . LEU A 1 74  ? -5.850  4.363   8.752   1.000 15.097 0 89   LEU A HD23 1 c 
ATOM   1140 N N    . TYR A 1 75  ? -6.426  9.617   5.226   1.000 10.952 0 90   TYR A N    1 ? 
ATOM   1141 C CA   . TYR A 1 75  ? -6.327  10.346  3.966   1.000 10.694 0 90   TYR A CA   1 ? 
ATOM   1142 C C    . TYR A 1 75  ? -5.091  11.226  4.004   1.000 11.308 0 90   TYR A C    1 ? 
ATOM   1143 O O    . TYR A 1 75  ? -4.328  11.301  3.024   1.000 12.159 0 90   TYR A O    1 ? 
ATOM   1144 C CB   . TYR A 1 75  ? -7.619  11.129  3.761   1.000 10.903 0 90   TYR A CB   1 ? 
ATOM   1145 C CG   . TYR A 1 75  ? -7.826  11.762  2.404   1.000 10.668 0 90   TYR A CG   1 ? 
ATOM   1146 C CD1  . TYR A 1 75  ? -7.298  13.008  2.081   1.000 11.774 0 90   TYR A CD1  1 ? 
ATOM   1147 C CD2  . TYR A 1 75  ? -8.629  11.172  1.457   1.000 11.045 0 90   TYR A CD2  1 ? 
ATOM   1148 C CE1  . TYR A 1 75  ? -7.553  13.605  0.856   1.000 12.380 0 90   TYR A CE1  1 ? 
ATOM   1149 C CE2  . TYR A 1 75  ? -8.891  11.744  0.225   1.000 11.904 0 90   TYR A CE2  1 ? 
ATOM   1150 C CZ   . TYR A 1 75  ? -8.354  12.979  -0.077  1.000 11.865 0 90   TYR A CZ   1 ? 
ATOM   1151 O OH   . TYR A 1 75  ? -8.640  13.595  -1.259  1.000 13.247 0 90   TYR A OH   1 ? 
ATOM   1152 H H    . TYR A 1 75  ? -7.172  9.740   5.739   1.000 10.986 0 90   TYR A H    1 c 
ATOM   1153 H HA   . TYR A 1 75  ? -6.230  9.690   3.226   1.000 10.891 0 90   TYR A HA   1 c 
ATOM   1154 H HB2  . TYR A 1 75  ? -8.372  10.523  3.938   1.000 10.807 0 90   TYR A HB2  1 c 
ATOM   1155 H HB3  . TYR A 1 75  ? -7.655  11.837  4.442   1.000 10.807 0 90   TYR A HB3  1 c 
ATOM   1156 H HD1  . TYR A 1 75  ? -6.760  13.461  2.711   1.000 11.737 0 90   TYR A HD1  1 c 
ATOM   1157 H HD2  . TYR A 1 75  ? -9.017  10.334  1.653   1.000 11.165 0 90   TYR A HD2  1 c 
ATOM   1158 H HE1  . TYR A 1 75  ? -7.187  14.451  0.662   1.000 12.104 0 90   TYR A HE1  1 c 
ATOM   1159 H HE2  . TYR A 1 75  ? -9.453  11.308  -0.393  1.000 11.694 0 90   TYR A HE2  1 c 
ATOM   1160 H HH   . TYR A 1 75  ? -8.050  13.391  -1.848  0.000 13.250 0 90   TYR A HH   1 c 
ATOM   1161 N N    . ALA A 1 76  ? -4.901  11.931  5.123   1.000 12.253 0 91   ALA A N    1 ? 
ATOM   1162 C CA   . ALA A 1 76  ? -3.743  12.786  5.300   1.000 14.270 0 91   ALA A CA   1 ? 
ATOM   1163 C C    . ALA A 1 76  ? -2.443  12.014  5.273   1.000 13.778 0 91   ALA A C    1 ? 
ATOM   1164 O O    . ALA A 1 76  ? -1.475  12.542  4.712   1.000 15.855 0 91   ALA A O    1 ? 
ATOM   1165 C CB   . ALA A 1 76  ? -3.874  13.560  6.604   1.000 14.834 0 91   ALA A CB   1 ? 
ATOM   1166 H H    . ALA A 1 76  ? -5.518  11.882  5.795   1.000 12.435 0 91   ALA A H    1 c 
ATOM   1167 H HA   . ALA A 1 76  ? -3.726  13.435  4.545   1.000 13.949 0 91   ALA A HA   1 c 
ATOM   1168 H HB1  . ALA A 1 76  ? -4.677  14.107  6.581   1.000 14.666 0 91   ALA A HB1  1 c 
ATOM   1169 H HB2  . ALA A 1 76  ? -3.931  12.939  7.349   1.000 14.666 0 91   ALA A HB2  1 c 
ATOM   1170 H HB3  . ALA A 1 76  ? -3.098  14.134  6.723   1.000 14.666 0 91   ALA A HB3  1 c 
ATOM   1171 N N    A ARG A 1 77  ? -2.403  10.791  5.833   0.500 12.522 0 92   ARG A N    1 ? 
ATOM   1172 N N    B ARG A 1 77  ? -2.381  10.819  5.850   0.500 13.267 0 92   ARG A N    1 ? 
ATOM   1173 C CA   A ARG A 1 77  ? -1.214  9.941   5.807   0.500 12.728 0 92   ARG A CA   1 ? 
ATOM   1174 C CA   B ARG A 1 77  ? -1.141  10.076  5.753   0.500 14.116 0 92   ARG A CA   1 ? 
ATOM   1175 C C    A ARG A 1 77  ? -0.848  9.576   4.353   0.500 12.423 0 92   ARG A C    1 ? 
ATOM   1176 C C    B ARG A 1 77  ? -0.858  9.810   4.269   0.500 13.459 0 92   ARG A C    1 ? 
ATOM   1177 O O    A ARG A 1 77  ? 0.321   9.495   3.948   0.500 11.167 0 92   ARG A O    1 ? 
ATOM   1178 O O    B ARG A 1 77  ? 0.241   10.074  3.782   0.500 11.950 0 92   ARG A O    1 ? 
ATOM   1179 C CB   A ARG A 1 77  ? -1.393  8.633   6.594   0.500 12.800 0 92   ARG A CB   1 ? 
ATOM   1180 C CB   B ARG A 1 77  ? -1.140  8.790   6.577   0.500 15.125 0 92   ARG A CB   1 ? 
ATOM   1181 C CG   A ARG A 1 77  ? -1.409  8.698   8.124   0.500 13.432 0 92   ARG A CG   1 ? 
ATOM   1182 C CG   B ARG A 1 77  ? -0.894  8.979   8.070   0.500 16.673 0 92   ARG A CG   1 ? 
ATOM   1183 C CD   A ARG A 1 77  ? -1.347  7.338   8.838   0.500 14.205 0 92   ARG A CD   1 ? 
ATOM   1184 C CD   B ARG A 1 77  ? -1.007  7.641   8.786   0.500 18.055 0 92   ARG A CD   1 ? 
ATOM   1185 N NE   A ARG A 1 77  ? -0.013  6.734   8.713   0.500 14.409 0 92   ARG A NE   1 ? 
ATOM   1186 N NE   B ARG A 1 77  ? -0.730  7.745   10.222  0.500 18.684 0 92   ARG A NE   1 ? 
ATOM   1187 C CZ   A ARG A 1 77  ? 0.402   5.529   9.160   0.500 14.616 0 92   ARG A CZ   1 ? 
ATOM   1188 C CZ   B ARG A 1 77  ? 0.481   7.803   10.741  0.500 20.440 0 92   ARG A CZ   1 ? 
ATOM   1189 N NH1  A ARG A 1 77  ? -0.360  4.668   9.847   0.500 14.224 0 92   ARG A NH1  1 ? 
ATOM   1190 N NH1  B ARG A 1 77  ? 1.545   7.614   9.979   0.500 22.045 0 92   ARG A NH1  1 ? 
ATOM   1191 N NH2  A ARG A 1 77  ? 1.650   5.188   8.920   0.500 14.634 0 92   ARG A NH2  1 ? 
ATOM   1192 N NH2  B ARG A 1 77  ? 0.622   8.066   12.026  0.500 21.024 0 92   ARG A NH2  1 ? 
ATOM   1193 H H    A ARG A 1 77  ? -3.151  10.475  6.254   0.500 12.854 0 92   ARG A H    1 c 
ATOM   1194 H H    B ARG A 1 77  ? -3.093  10.467  6.303   0.500 13.566 0 92   ARG A H    1 c 
ATOM   1195 H HA   A ARG A 1 77  ? -0.461  10.450  6.204   0.500 12.645 0 92   ARG A HA   1 c 
ATOM   1196 H HA   B ARG A 1 77  ? -0.414  10.652  6.104   0.500 14.011 0 92   ARG A HA   1 c 
ATOM   1197 H HB2  A ARG A 1 77  ? -2.234  8.223   6.301   0.500 12.919 0 92   ARG A HB2  1 c 
ATOM   1198 H HB2  B ARG A 1 77  ? -2.006  8.344   6.457   0.500 15.224 0 92   ARG A HB2  1 c 
ATOM   1199 H HB3  A ARG A 1 77  ? -0.671  8.025   6.326   0.500 12.924 0 92   ARG A HB3  1 c 
ATOM   1200 H HB3  B ARG A 1 77  ? -0.449  8.193   6.219   0.500 15.224 0 92   ARG A HB3  1 c 
ATOM   1201 H HG2  A ARG A 1 77  ? -0.649  9.242   8.423   0.500 13.455 0 92   ARG A HG2  1 c 
ATOM   1202 H HG2  B ARG A 1 77  ? 0.003   9.351   8.213   0.500 16.666 0 92   ARG A HG2  1 c 
ATOM   1203 H HG3  A ARG A 1 77  ? -2.224  9.163   8.411   0.500 13.453 0 92   ARG A HG3  1 c 
ATOM   1204 H HG3  B ARG A 1 77  ? -1.558  9.602   8.438   0.500 16.630 0 92   ARG A HG3  1 c 
ATOM   1205 H HD2  A ARG A 1 77  ? -1.560  7.458   9.786   0.500 14.075 0 92   ARG A HD2  1 c 
ATOM   1206 H HD2  B ARG A 1 77  ? -1.910  7.286   8.658   0.500 17.878 0 92   ARG A HD2  1 c 
ATOM   1207 H HD3  A ARG A 1 77  ? -2.013  6.735   8.450   0.500 14.070 0 92   ARG A HD3  1 c 
ATOM   1208 H HD3  B ARG A 1 77  ? -0.377  7.009   8.382   0.500 17.878 0 92   ARG A HD3  1 c 
ATOM   1209 H HE   A ARG A 1 77  ? 0.590   7.207   8.299   0.500 14.410 0 92   ARG A HE   1 c 
ATOM   1210 H HE   B ARG A 1 77  ? -1.407  7.771   10.769  0.500 18.936 0 92   ARG A HE   1 c 
ATOM   1211 H HH11 A ARG A 1 77  ? -0.017  3.898   10.112  0.500 14.344 0 92   ARG A HH11 1 c 
ATOM   1212 H HH11 B ARG A 1 77  ? 2.353   7.652   10.335  0.500 21.538 0 92   ARG A HH11 1 c 
ATOM   1213 H HH12 A ARG A 1 77  ? -1.199  4.873   10.032  0.500 14.344 0 92   ARG A HH12 1 c 
ATOM   1214 H HH12 B ARG A 1 77  ? 1.443   7.450   9.116   0.500 21.538 0 92   ARG A HH12 1 c 
ATOM   1215 H HH21 A ARG A 1 77  ? 1.953   4.406   9.200   0.500 14.628 0 92   ARG A HH21 1 c 
ATOM   1216 H HH21 B ARG A 1 77  ? 1.349   7.796   12.452  0.500 20.843 0 92   ARG A HH21 1 c 
ATOM   1217 H HH22 A ARG A 1 77  ? 2.180   5.743   8.481   0.500 14.628 0 92   ARG A HH22 1 c 
ATOM   1218 H HH22 B ARG A 1 77  ? -0.009  8.512   12.455  0.500 20.843 0 92   ARG A HH22 1 c 
ATOM   1219 N N    . PHE A 1 78  ? -1.866  9.352   3.515   1.000 12.233 0 93   PHE A N    1 ? 
ATOM   1220 C CA   . PHE A 1 78  ? -1.631  9.022   2.112   1.000 11.419 0 93   PHE A CA   1 ? 
ATOM   1221 C C    . PHE A 1 78  ? -1.165  10.241  1.328   1.000 12.192 0 93   PHE A C    1 ? 
ATOM   1222 O O    . PHE A 1 78  ? -0.146  10.168  0.628   1.000 12.792 0 93   PHE A O    1 ? 
ATOM   1223 C CB   . PHE A 1 78  ? -2.868  8.367   1.496   1.000 11.410 0 93   PHE A CB   1 ? 
ATOM   1224 C CG   . PHE A 1 78  ? -2.601  7.871   0.065   1.000 12.768 0 93   PHE A CG   1 ? 
ATOM   1225 C CD1  . PHE A 1 78  ? -1.940  6.666   -0.141  1.000 12.754 0 93   PHE A CD1  1 ? 
ATOM   1226 C CD2  . PHE A 1 78  ? -3.015  8.612   -1.052  1.000 12.730 0 93   PHE A CD2  1 ? 
ATOM   1227 C CE1  . PHE A 1 78  ? -1.700  6.205   -1.429  1.000 13.780 0 93   PHE A CE1  1 ? 
ATOM   1228 C CE2  . PHE A 1 78  ? -2.762  8.114   -2.335  1.000 13.045 0 93   PHE A CE2  1 ? 
ATOM   1229 C CZ   . PHE A 1 78  ? -2.143  6.916   -2.507  1.000 14.202 0 93   PHE A CZ   1 ? 
ATOM   1230 H H    . PHE A 1 78  ? -2.716  9.322   3.847   1.000 12.355 0 93   PHE A H    1 c 
ATOM   1231 H HA   . PHE A 1 78  ? -0.898  8.351   2.083   1.000 11.737 0 93   PHE A HA   1 c 
ATOM   1232 H HB2  . PHE A 1 78  ? -3.138  7.607   2.057   1.000 11.705 0 93   PHE A HB2  1 c 
ATOM   1233 H HB3  . PHE A 1 78  ? -3.600  9.022   1.480   1.000 11.705 0 93   PHE A HB3  1 c 
ATOM   1234 H HD1  . PHE A 1 78  ? -1.657  6.156   0.601   1.000 12.991 0 93   PHE A HD1  1 c 
ATOM   1235 H HD2  . PHE A 1 78  ? -3.472  9.430   -0.938  1.000 12.817 0 93   PHE A HD2  1 c 
ATOM   1236 H HE1  . PHE A 1 78  ? -1.261  5.379   -1.557  1.000 13.612 0 93   PHE A HE1  1 c 
ATOM   1237 H HE2  . PHE A 1 78  ? -3.049  8.604   -3.089  1.000 13.232 0 93   PHE A HE2  1 c 
ATOM   1238 H HZ   . PHE A 1 78  ? -1.959  6.605   -3.379  1.000 13.770 0 93   PHE A HZ   1 c 
ATOM   1239 N N    . THR A 1 79  ? -1.879  11.349  1.447   1.000 13.144 0 94   THR A N    1 ? 
ATOM   1240 C CA   . THR A 1 79  ? -1.534  12.481  0.593   1.000 16.112 0 94   THR A CA   1 ? 
ATOM   1241 C C    . THR A 1 79  ? -0.197  13.055  1.042   1.000 18.443 0 94   THR A C    1 ? 
ATOM   1242 O O    . THR A 1 79  ? 0.546   13.468  0.148   1.000 17.738 0 94   THR A O    1 ? 
ATOM   1243 C CB   . THR A 1 79  ? -2.662  13.514  0.488   1.000 18.363 0 94   THR A CB   1 ? 
ATOM   1244 O OG1  . THR A 1 79  ? -2.829  14.003  1.808   1.000 21.082 0 94   THR A OG1  1 ? 
ATOM   1245 C CG2  . THR A 1 79  ? -3.931  12.911  -0.081  1.000 19.879 0 94   THR A CG2  1 ? 
ATOM   1246 H H    . THR A 1 79  ? -2.571  11.413  2.041   1.000 13.486 0 94   THR A H    1 c 
ATOM   1247 H HA   . THR A 1 79  ? -1.401  12.121  -0.312  1.000 16.232 0 94   THR A HA   1 c 
ATOM   1248 H HB   . THR A 1 79  ? -2.372  14.255  -0.097  1.000 18.695 0 94   THR A HB   1 c 
ATOM   1249 H HG1  . THR A 1 79  ? -3.041  13.349  2.333   0.000 21.120 0 94   THR A HG1  1 c 
ATOM   1250 H HG21 . THR A 1 79  ? -4.613  13.600  -0.155  1.000 19.396 0 94   THR A HG21 1 c 
ATOM   1251 H HG22 . THR A 1 79  ? -4.248  12.205  0.506   1.000 19.326 0 94   THR A HG22 1 c 
ATOM   1252 H HG23 . THR A 1 79  ? -3.748  12.542  -0.962  1.000 19.396 0 94   THR A HG23 1 c 
ATOM   1253 N N    . ALA A 1 80  ? 0.151   13.001  2.358   1.000 16.999 0 95   ALA A N    1 ? 
ATOM   1254 C CA   . ALA A 1 80  ? 1.462   13.476  2.821   1.000 18.568 0 95   ALA A CA   1 ? 
ATOM   1255 C C    . ALA A 1 80  ? 2.580   12.627  2.222   1.000 17.208 0 95   ALA A C    1 ? 
ATOM   1256 O O    . ALA A 1 80  ? 3.591   13.192  1.772   1.000 20.695 0 95   ALA A O    1 ? 
ATOM   1257 C CB   . ALA A 1 80  ? 1.588   13.500  4.315   1.000 19.495 0 95   ALA A CB   1 ? 
ATOM   1258 H H    . ALA A 1 80  ? -0.441  12.670  2.970   1.000 17.652 0 95   ALA A H    1 c 
ATOM   1259 H HA   . ALA A 1 80  ? 1.579   14.406  2.483   1.000 18.179 0 95   ALA A HA   1 c 
ATOM   1260 H HB1  . ALA A 1 80  ? 0.914   14.092  4.690   1.000 19.273 0 95   ALA A HB1  1 c 
ATOM   1261 H HB2  . ALA A 1 80  ? 1.460   12.604  4.669   1.000 19.225 0 95   ALA A HB2  1 c 
ATOM   1262 H HB3  . ALA A 1 80  ? 2.471   13.821  4.564   1.000 19.216 0 95   ALA A HB3  1 c 
ATOM   1263 N N    A GLN A 1 81  ? 2.433   11.311  2.228   0.500 16.952 0 96   GLN A N    1 ? 
ATOM   1264 N N    B GLN A 1 81  ? 2.376   11.289  2.202   0.500 15.790 0 96   GLN A N    1 ? 
ATOM   1265 C CA   A GLN A 1 81  ? 3.495   10.509  1.680   0.500 16.963 0 96   GLN A CA   1 ? 
ATOM   1266 C CA   B GLN A 1 81  ? 3.321   10.280  1.726   0.500 14.610 0 96   GLN A CA   1 ? 
ATOM   1267 C C    A GLN A 1 81  ? 3.684   10.862  0.205   0.500 15.029 0 96   GLN A C    1 ? 
ATOM   1268 C C    B GLN A 1 81  ? 3.626   10.480  0.227   0.500 14.634 0 96   GLN A C    1 ? 
ATOM   1269 O O    A GLN A 1 81  ? 4.806   11.119  -0.250  0.500 13.397 0 96   GLN A O    1 ? 
ATOM   1270 O O    B GLN A 1 81  ? 4.778   10.263  -0.200  0.500 13.976 0 96   GLN A O    1 ? 
ATOM   1271 C CB   A GLN A 1 81  ? 3.220   9.022   1.829   0.500 17.950 0 96   GLN A CB   1 ? 
ATOM   1272 C CB   B GLN A 1 81  ? 2.851   8.837   1.970   0.500 14.574 0 96   GLN A CB   1 ? 
ATOM   1273 C CG   A GLN A 1 81  ? 4.241   8.164   1.093   0.500 19.892 0 96   GLN A CG   1 ? 
ATOM   1274 C CG   B GLN A 1 81  ? 3.086   8.312   3.393   0.500 14.305 0 96   GLN A CG   1 ? 
ATOM   1275 C CD   A GLN A 1 81  ? 4.132   6.694   1.415   0.500 22.458 0 96   GLN A CD   1 ? 
ATOM   1276 C CD   B GLN A 1 81  ? 2.588   6.905   3.662   0.500 14.746 0 96   GLN A CD   1 ? 
ATOM   1277 O OE1  A GLN A 1 81  ? 5.097   5.933   1.285   0.500 23.432 0 96   GLN A OE1  1 ? 
ATOM   1278 O OE1  B GLN A 1 81  ? 2.653   6.021   2.813   0.500 15.295 0 96   GLN A OE1  1 ? 
ATOM   1279 N NE2  A GLN A 1 81  ? 2.970   6.312   1.913   0.500 23.386 0 96   GLN A NE2  1 ? 
ATOM   1280 N NE2  B GLN A 1 81  ? 2.104   6.641   4.868   0.500 14.359 0 96   GLN A NE2  1 ? 
ATOM   1281 H H    A GLN A 1 81  ? 1.686   10.913  2.572   0.500 17.025 0 96   GLN A H    1 c 
ATOM   1282 H H    B GLN A 1 81  ? 1.574   10.987  2.521   0.500 15.859 0 96   GLN A H    1 c 
ATOM   1283 H HA   A GLN A 1 81  ? 4.332   10.724  2.166   0.500 16.785 0 96   GLN A HA   1 c 
ATOM   1284 H HA   B GLN A 1 81  ? 4.167   10.404  2.226   0.500 14.831 0 96   GLN A HA   1 c 
ATOM   1285 H HB2  A GLN A 1 81  ? 3.230   8.789   2.781   0.500 18.138 0 96   GLN A HB2  1 c 
ATOM   1286 H HB2  B GLN A 1 81  ? 1.893   8.785   1.770   0.500 14.511 0 96   GLN A HB2  1 c 
ATOM   1287 H HB3  A GLN A 1 81  ? 2.325   8.826   1.481   0.500 18.138 0 96   GLN A HB3  1 c 
ATOM   1288 H HB3  B GLN A 1 81  ? 3.315   8.249   1.337   0.500 14.519 0 96   GLN A HB3  1 c 
ATOM   1289 H HG2  A GLN A 1 81  ? 4.125   8.283   0.126   0.500 19.987 0 96   GLN A HG2  1 c 
ATOM   1290 H HG2  B GLN A 1 81  ? 4.048   8.338   3.585   0.500 14.484 0 96   GLN A HG2  1 c 
ATOM   1291 H HG3  A GLN A 1 81  ? 5.145   8.469   1.323   0.500 19.987 0 96   GLN A HG3  1 c 
ATOM   1292 H HG3  B GLN A 1 81  ? 2.647   8.914   4.026   0.500 14.557 0 96   GLN A HG3  1 c 
ATOM   1293 H HE21 A GLN A 1 81  ? 2.323   6.906   2.035   0.500 23.096 0 96   GLN A HE21 1 c 
ATOM   1294 H HE21 B GLN A 1 81  ? 2.080   7.278   5.484   0.500 14.477 0 96   GLN A HE21 1 c 
ATOM   1295 H HE22 A GLN A 1 81  ? 2.838   5.460   2.125   0.500 23.096 0 96   GLN A HE22 1 c 
ATOM   1296 H HE22 B GLN A 1 81  ? 1.804   5.828   5.056   0.500 14.477 0 96   GLN A HE22 1 c 
ATOM   1297 N N    . ILE A 1 82  ? 2.596   10.842  -0.563  1.000 14.182 0 97   ILE A N    1 ? 
ATOM   1298 C CA   . ILE A 1 82  ? 2.736   11.031  -2.015  1.000 14.538 0 97   ILE A CA   1 ? 
ATOM   1299 C C    . ILE A 1 82  ? 3.299   12.410  -2.316  1.000 15.121 0 97   ILE A C    1 ? 
ATOM   1300 O O    . ILE A 1 82  ? 4.200   12.535  -3.160  1.000 16.217 0 97   ILE A O    1 ? 
ATOM   1301 C CB   . ILE A 1 82  ? 1.398   10.779  -2.754  1.000 14.437 0 97   ILE A CB   1 ? 
ATOM   1302 C CG1  . ILE A 1 82  ? 0.835   9.410   -2.476  1.000 15.339 0 97   ILE A CG1  1 ? 
ATOM   1303 C CG2  . ILE A 1 82  ? 1.448   11.011  -4.270  1.000 15.433 0 97   ILE A CG2  1 ? 
ATOM   1304 C CD1  . ILE A 1 82  ? 1.716   8.263   -2.821  1.000 14.844 0 97   ILE A CD1  1 ? 
ATOM   1305 H H    . ILE A 1 82  ? 1.760   10.855  -0.195  1.000 14.531 0 97   ILE A H    1 c 
ATOM   1306 H HA   . ILE A 1 82  ? 3.379   10.372  -2.340  1.000 14.563 0 97   ILE A HA   1 c 
ATOM   1307 H HB   . ILE A 1 82  ? 0.756   11.423  -2.392  1.000 14.807 0 97   ILE A HB   1 c 
ATOM   1308 H HG12 . ILE A 1 82  ? 0.616   9.353   -1.525  1.000 14.990 0 97   ILE A HG12 1 c 
ATOM   1309 H HG13 . ILE A 1 82  ? -0.003  9.315   -2.974  1.000 15.010 0 97   ILE A HG13 1 c 
ATOM   1310 H HG21 . ILE A 1 82  ? 0.602   10.749  -4.669  1.000 15.098 0 97   ILE A HG21 1 c 
ATOM   1311 H HG22 . ILE A 1 82  ? 2.165   10.481  -4.658  1.000 15.126 0 97   ILE A HG22 1 c 
ATOM   1312 H HG23 . ILE A 1 82  ? 1.610   11.952  -4.452  1.000 15.126 0 97   ILE A HG23 1 c 
ATOM   1313 H HD11 . ILE A 1 82  ? 2.012   8.339   -3.748  1.000 14.993 0 97   ILE A HD11 1 c 
ATOM   1314 H HD12 . ILE A 1 82  ? 1.218   7.431   -2.708  1.000 14.991 0 97   ILE A HD12 1 c 
ATOM   1315 H HD13 . ILE A 1 82  ? 2.494   8.254   -2.232  1.000 14.986 0 97   ILE A HD13 1 c 
ATOM   1316 N N    . ARG A 1 83  ? 2.750   13.456  -1.715  1.000 17.418 0 98   ARG A N    1 ? 
ATOM   1317 C CA   . ARG A 1 83  ? 3.204   14.805  -2.027  1.000 21.307 0 98   ARG A CA   1 ? 
ATOM   1318 C C    . ARG A 1 83  ? 4.661   14.995  -1.627  1.000 21.274 0 98   ARG A C    1 ? 
ATOM   1319 O O    . ARG A 1 83  ? 5.401   15.682  -2.331  1.000 24.096 0 98   ARG A O    1 ? 
ATOM   1320 C CB   . ARG A 1 83  ? 2.288   15.865  -1.408  1.000 24.655 0 98   ARG A CB   1 ? 
ATOM   1321 C CG   . ARG A 1 83  ? 1.039   15.868  -2.287  1.000 32.977 0 98   ARG A CG   1 ? 
ATOM   1322 C CD   . ARG A 1 83  ? -0.183  16.730  -1.895  1.000 39.110 0 98   ARG A CD   1 ? 
ATOM   1323 N NE   . ARG A 1 83  ? -1.377  16.154  -2.531  1.000 38.562 0 98   ARG A NE   1 ? 
ATOM   1324 C CZ   . ARG A 1 83  ? -2.666  16.397  -2.219  1.000 50.621 0 98   ARG A CZ   1 ? 
ATOM   1325 N NH1  . ARG A 1 83  ? -2.998  17.298  -1.308  1.000 51.479 0 98   ARG A NH1  1 ? 
ATOM   1326 N NH2  . ARG A 1 83  ? -3.639  15.722  -2.814  1.000 52.914 0 98   ARG A NH2  1 ? 
ATOM   1327 H H    . ARG A 1 83  ? 2.081   13.338  -1.103  1.000 17.661 0 98   ARG A H    1 c 
ATOM   1328 H HA   . ARG A 1 83  ? 3.153   14.915  -3.011  1.000 21.095 0 98   ARG A HA   1 c 
ATOM   1329 H HB2  . ARG A 1 83  ? 2.055   15.630  -0.484  1.000 25.380 0 98   ARG A HB2  1 c 
ATOM   1330 H HB3  . ARG A 1 83  ? 2.715   16.748  -1.421  1.000 25.448 0 98   ARG A HB3  1 c 
ATOM   1331 H HG2  . ARG A 1 83  ? 1.312   16.137  -3.191  1.000 31.857 0 98   ARG A HG2  1 c 
ATOM   1332 H HG3  . ARG A 1 83  ? 0.733   14.939  -2.371  1.000 31.920 0 98   ARG A HG3  1 c 
ATOM   1333 H HD2  . ARG A 1 83  ? -0.298  16.734  -0.924  1.000 37.599 0 98   ARG A HD2  1 c 
ATOM   1334 H HD3  . ARG A 1 83  ? -0.060  17.652  -2.200  1.000 37.554 0 98   ARG A HD3  1 c 
ATOM   1335 H HE   . ARG A 1 83  ? -1.244  15.598  -3.188  1.000 41.261 0 98   ARG A HE   1 c 
ATOM   1336 H HH11 . ARG A 1 83  ? -3.783  17.243  -0.899  1.000 51.211 0 98   ARG A HH11 1 c 
ATOM   1337 H HH12 . ARG A 1 83  ? -2.437  17.955  -1.111  1.000 51.128 0 98   ARG A HH12 1 c 
ATOM   1338 H HH21 . ARG A 1 83  ? -4.468  15.782  -2.513  1.000 51.869 0 98   ARG A HH21 1 c 
ATOM   1339 H HH22 . ARG A 1 83  ? -3.457  15.213  -3.511  1.000 50.851 0 98   ARG A HH22 1 c 
ATOM   1340 N N    . GLY A 1 84  ? 5.054   14.433  -0.493  1.000 18.481 0 99   GLY A N    1 ? 
ATOM   1341 C CA   . GLY A 1 84  ? 6.438   14.539  -0.050  1.000 19.436 0 99   GLY A CA   1 ? 
ATOM   1342 C C    . GLY A 1 84  ? 7.454   13.823  -0.958  1.000 18.993 0 99   GLY A C    1 ? 
ATOM   1343 O O    . GLY A 1 84  ? 8.601   14.255  -1.089  1.000 19.659 0 99   GLY A O    1 ? 
ATOM   1344 H H    . GLY A 1 84  ? 4.455   13.977  0.026   1.000 19.329 0 99   GLY A H    1 c 
ATOM   1345 H HA2  . GLY A 1 84  ? 6.676   15.494  0.006   1.000 19.139 0 99   GLY A HA2  1 c 
ATOM   1346 H HA3  . GLY A 1 84  ? 6.504   14.164  0.860   1.000 19.112 0 99   GLY A HA3  1 c 
ATOM   1347 N N    . ALA A 1 85  ? 7.061   12.665  -1.524  1.000 15.266 0 100  ALA A N    1 ? 
ATOM   1348 C CA   . ALA A 1 85  ? 7.980   11.798  -2.228  1.000 15.271 0 100  ALA A CA   1 ? 
ATOM   1349 C C    . ALA A 1 85  ? 7.990   12.103  -3.725  1.000 15.676 0 100  ALA A C    1 ? 
ATOM   1350 O O    . ALA A 1 85  ? 8.982   11.816  -4.361  1.000 15.948 0 100  ALA A O    1 ? 
ATOM   1351 C CB   . ALA A 1 85  ? 7.646   10.342  -1.929  1.000 15.184 0 100  ALA A CB   1 ? 
ATOM   1352 H H    . ALA A 1 85  ? 6.185   12.412  -1.458  1.000 16.110 0 100  ALA A H    1 c 
ATOM   1353 H HA   . ALA A 1 85  ? 8.896   11.981  -1.880  1.000 15.369 0 100  ALA A HA   1 c 
ATOM   1354 H HB1  . ALA A 1 85  ? 7.748   10.172  -0.978  1.000 15.290 0 100  ALA A HB1  1 c 
ATOM   1355 H HB2  . ALA A 1 85  ? 6.729   10.156  -2.192  1.000 15.229 0 100  ALA A HB2  1 c 
ATOM   1356 H HB3  . ALA A 1 85  ? 8.247   9.761   -2.426  1.000 15.229 0 100  ALA A HB3  1 c 
ATOM   1357 N N    . VAL A 1 86  ? 6.942   12.715  -4.284  1.000 15.305 0 101  VAL A N    1 ? 
ATOM   1358 C CA   . VAL A 1 86  ? 6.850   13.024  -5.710  1.000 16.677 0 101  VAL A CA   1 ? 
ATOM   1359 C C    . VAL A 1 86  ? 6.838   14.558  -5.876  1.000 17.799 0 101  VAL A C    1 ? 
ATOM   1360 O O    . VAL A 1 86  ? 5.804   15.244  -5.726  1.000 21.084 0 101  VAL A O    1 ? 
ATOM   1361 C CB   . VAL A 1 86  ? 5.567   12.395  -6.308  1.000 14.338 0 101  VAL A CB   1 ? 
ATOM   1362 C CG1  . VAL A 1 86  ? 5.531   12.620  -7.809  1.000 14.244 0 101  VAL A CG1  1 ? 
ATOM   1363 C CG2  . VAL A 1 86  ? 5.272   10.917  -6.000  1.000 14.261 0 101  VAL A CG2  1 ? 
ATOM   1364 H H    . VAL A 1 86  ? 6.240   12.952  -3.749  1.000 15.691 0 101  VAL A H    1 c 
ATOM   1365 H HA   . VAL A 1 86  ? 7.628   12.655  -6.170  1.000 16.177 0 101  VAL A HA   1 c 
ATOM   1366 H HB   . VAL A 1 86  ? 4.810   12.904  -5.934  1.000 14.756 0 101  VAL A HB   1 c 
ATOM   1367 H HG11 . VAL A 1 86  ? 6.357   12.296  -8.206  1.000 14.276 0 101  VAL A HG11 1 c 
ATOM   1368 H HG12 . VAL A 1 86  ? 5.433   13.569  -7.995  1.000 14.289 0 101  VAL A HG12 1 c 
ATOM   1369 H HG13 . VAL A 1 86  ? 4.778   12.139  -8.191  1.000 14.276 0 101  VAL A HG13 1 c 
ATOM   1370 H HG21 . VAL A 1 86  ? 4.420   10.666  -6.395  1.000 14.282 0 101  VAL A HG21 1 c 
ATOM   1371 H HG22 . VAL A 1 86  ? 5.233   10.786  -5.037  1.000 14.286 0 101  VAL A HG22 1 c 
ATOM   1372 H HG23 . VAL A 1 86  ? 5.977   10.361  -6.373  1.000 14.272 0 101  VAL A HG23 1 c 
ATOM   1373 N N    . ASP A 1 87  ? 7.965   15.105  -6.299  1.000 19.298 0 102  ASP A N    1 ? 
ATOM   1374 C CA   . ASP A 1 87  ? 8.099   16.508  -6.613  1.000 18.782 0 102  ASP A CA   1 ? 
ATOM   1375 C C    . ASP A 1 87  ? 7.698   16.734  -8.070  1.000 16.176 0 102  ASP A C    1 ? 
ATOM   1376 O O    . ASP A 1 87  ? 8.495   16.523  -8.946  1.000 16.309 0 102  ASP A O    1 ? 
ATOM   1377 C CB   . ASP A 1 87  ? 9.538   16.897  -6.319  1.000 20.655 0 102  ASP A CB   1 ? 
ATOM   1378 C CG   . ASP A 1 87  ? 9.855   18.371  -6.519  1.000 22.527 0 102  ASP A CG   1 ? 
ATOM   1379 O OD1  . ASP A 1 87  ? 8.958   19.093  -7.001  1.000 20.658 0 102  ASP A OD1  1 ? 
ATOM   1380 O OD2  . ASP A 1 87  ? 11.014  18.756  -6.245  1.000 25.597 0 102  ASP A OD2  1 ? 
ATOM   1381 H H    . ASP A 1 87  ? 8.699   14.569  -6.398  1.000 18.799 0 102  ASP A H    1 c 
ATOM   1382 H HA   . ASP A 1 87  ? 7.503   17.025  -6.026  1.000 18.701 0 102  ASP A HA   1 c 
ATOM   1383 H HB2  . ASP A 1 87  ? 9.740   16.666  -5.388  1.000 20.611 0 102  ASP A HB2  1 c 
ATOM   1384 H HB3  . ASP A 1 87  ? 10.135  16.375  -6.894  1.000 20.582 0 102  ASP A HB3  1 c 
ATOM   1385 N N    . LEU A 1 88  ? 6.490   17.270  -8.314  1.000 16.811 0 103  LEU A N    1 ? 
ATOM   1386 C CA   . LEU A 1 88  ? 5.996   17.484  -9.666  1.000 16.277 0 103  LEU A CA   1 ? 
ATOM   1387 C C    . LEU A 1 88  ? 6.832   18.454  -10.480 1.000 19.476 0 103  LEU A C    1 ? 
ATOM   1388 O O    . LEU A 1 88  ? 6.770   18.431  -11.710 1.000 20.555 0 103  LEU A O    1 ? 
ATOM   1389 C CB   . LEU A 1 88  ? 4.547   17.961  -9.690  1.000 18.468 0 103  LEU A CB   1 ? 
ATOM   1390 C CG   . LEU A 1 88  ? 3.510   16.973  -9.179  1.000 17.488 0 103  LEU A CG   1 ? 
ATOM   1391 C CD1  . LEU A 1 88  ? 2.133   17.600  -9.207  1.000 18.975 0 103  LEU A CD1  1 ? 
ATOM   1392 C CD2  . LEU A 1 88  ? 3.500   15.723  -10.060 1.000 17.482 0 103  LEU A CD2  1 ? 
ATOM   1393 H H    . LEU A 1 88  ? 5.959   17.510  -7.610  1.000 16.579 0 103  LEU A H    1 c 
ATOM   1394 H HA   . LEU A 1 88  ? 6.041   16.611  -10.130 1.000 17.330 0 103  LEU A HA   1 c 
ATOM   1395 H HB2  . LEU A 1 88  ? 4.486   18.782  -9.150  1.000 17.724 0 103  LEU A HB2  1 c 
ATOM   1396 H HB3  . LEU A 1 88  ? 4.317   18.198  -10.617 1.000 17.736 0 103  LEU A HB3  1 c 
ATOM   1397 H HG   . LEU A 1 88  ? 3.737   16.718  -8.248  1.000 17.934 0 103  LEU A HG   1 c 
ATOM   1398 H HD11 . LEU A 1 88  ? 2.126   18.393  -8.645  1.000 18.519 0 103  LEU A HD11 1 c 
ATOM   1399 H HD12 . LEU A 1 88  ? 1.479   16.963  -8.874  1.000 18.514 0 103  LEU A HD12 1 c 
ATOM   1400 H HD13 . LEU A 1 88  ? 1.907   17.849  -10.119 1.000 18.519 0 103  LEU A HD13 1 c 
ATOM   1401 H HD21 . LEU A 1 88  ? 4.301   15.199  -9.892  1.000 17.480 0 103  LEU A HD21 1 c 
ATOM   1402 H HD22 . LEU A 1 88  ? 3.474   15.985  -10.996 1.000 17.486 0 103  LEU A HD22 1 c 
ATOM   1403 H HD23 . LEU A 1 88  ? 2.716   15.186  -9.853  1.000 17.497 0 103  LEU A HD23 1 c 
ATOM   1404 N N    . SER A 1 89  ? 7.587   19.360  -9.817  1.000 17.937 0 104  SER A N    1 ? 
ATOM   1405 C CA   . SER A 1 89  ? 8.395   20.318  -10.556 1.000 18.438 0 104  SER A CA   1 ? 
ATOM   1406 C C    . SER A 1 89  ? 9.506   19.650  -11.341 1.000 19.368 0 104  SER A C    1 ? 
ATOM   1407 O O    . SER A 1 89  ? 10.034  20.264  -12.266 1.000 21.386 0 104  SER A O    1 ? 
ATOM   1408 C CB   . SER A 1 89  ? 8.987   21.381  -9.650  1.000 20.304 0 104  SER A CB   1 ? 
ATOM   1409 O OG   . SER A 1 89  ? 10.069  20.886  -8.879  1.000 19.546 0 104  SER A OG   1 ? 
ATOM   1410 H H    . SER A 1 89  ? 7.585   19.387  -8.903  1.000 18.379 0 104  SER A H    1 c 
ATOM   1411 H HA   . SER A 1 89  ? 7.800   20.772  -11.206 1.000 18.852 0 104  SER A HA   1 c 
ATOM   1412 H HB2  . SER A 1 89  ? 9.298   22.126  -10.196 1.000 19.687 0 104  SER A HB2  1 c 
ATOM   1413 H HB3  . SER A 1 89  ? 8.292   21.715  -9.052  1.000 19.688 0 104  SER A HB3  1 c 
ATOM   1414 H HG   . SER A 1 89  ? 10.361  21.514  -8.391  0.000 19.520 0 104  SER A HG   1 c 
ATOM   1415 N N    . LEU A 1 90  ? 9.876   18.415  -10.952 1.000 18.938 0 105  LEU A N    1 ? 
ATOM   1416 C CA   . LEU A 1 90  ? 10.920  17.689  -11.648 1.000 21.138 0 105  LEU A CA   1 ? 
ATOM   1417 C C    . LEU A 1 90  ? 10.368  17.096  -12.949 1.000 18.859 0 105  LEU A C    1 ? 
ATOM   1418 O O    . LEU A 1 90  ? 11.161  16.618  -13.753 1.000 21.732 0 105  LEU A O    1 ? 
ATOM   1419 C CB   . LEU A 1 90  ? 11.471  16.613  -10.715 1.000 23.478 0 105  LEU A CB   1 ? 
ATOM   1420 C CG   . LEU A 1 90  ? 12.061  17.106  -9.388  1.000 26.262 0 105  LEU A CG   1 ? 
ATOM   1421 C CD1  . LEU A 1 90  ? 12.636  15.951  -8.592  1.000 28.484 0 105  LEU A CD1  1 ? 
ATOM   1422 C CD2  . LEU A 1 90  ? 13.120  18.179  -9.635  1.000 29.345 0 105  LEU A CD2  1 ? 
ATOM   1423 H H    . LEU A 1 90  ? 9.476   18.026  -10.229 1.000 19.599 0 105  LEU A H    1 c 
ATOM   1424 H HA   . LEU A 1 90  ? 11.645  18.325  -11.876 1.000 20.729 0 105  LEU A HA   1 c 
ATOM   1425 H HB2  . LEU A 1 90  ? 10.744  15.980  -10.515 1.000 23.474 0 105  LEU A HB2  1 c 
ATOM   1426 H HB3  . LEU A 1 90  ? 12.171  16.116  -11.200 1.000 23.504 0 105  LEU A HB3  1 c 
ATOM   1427 H HG   . LEU A 1 90  ? 11.329  17.512  -8.856  1.000 26.545 0 105  LEU A HG   1 c 
ATOM   1428 H HD11 . LEU A 1 90  ? 11.935  15.303  -8.406  1.000 27.808 0 105  LEU A HD11 1 c 
ATOM   1429 H HD12 . LEU A 1 90  ? 12.999  16.282  -7.754  1.000 27.811 0 105  LEU A HD12 1 c 
ATOM   1430 H HD13 . LEU A 1 90  ? 13.343  15.523  -9.104  1.000 27.808 0 105  LEU A HD13 1 c 
ATOM   1431 H HD21 . LEU A 1 90  ? 12.688  19.005  -9.913  1.000 28.295 0 105  LEU A HD21 1 c 
ATOM   1432 H HD22 . LEU A 1 90  ? 13.728  17.882  -10.332 1.000 28.377 0 105  LEU A HD22 1 c 
ATOM   1433 H HD23 . LEU A 1 90  ? 13.619  18.337  -8.816  1.000 28.374 0 105  LEU A HD23 1 c 
ATOM   1434 N N    . TYR A 1 91  ? 9.025   17.082  -13.097 1.000 18.959 0 106  TYR A N    1 ? 
ATOM   1435 C CA   . TYR A 1 91  ? 8.315   16.400  -14.179 1.000 19.807 0 106  TYR A CA   1 ? 
ATOM   1436 C C    . TYR A 1 91  ? 7.269   17.301  -14.825 1.000 21.874 0 106  TYR A C    1 ? 
ATOM   1437 O O    . TYR A 1 91  ? 6.058   17.083  -14.698 1.000 20.408 0 106  TYR A O    1 ? 
ATOM   1438 C CB   . TYR A 1 91  ? 7.573   15.168  -13.646 1.000 17.480 0 106  TYR A CB   1 ? 
ATOM   1439 C CG   . TYR A 1 91  ? 8.449   14.236  -12.848 1.000 15.943 0 106  TYR A CG   1 ? 
ATOM   1440 C CD1  . TYR A 1 91  ? 9.235   13.276  -13.467 1.000 15.777 0 106  TYR A CD1  1 ? 
ATOM   1441 C CD2  . TYR A 1 91  ? 8.499   14.325  -11.465 1.000 16.127 0 106  TYR A CD2  1 ? 
ATOM   1442 C CE1  . TYR A 1 91  ? 10.028  12.422  -12.723 1.000 16.669 0 106  TYR A CE1  1 ? 
ATOM   1443 C CE2  . TYR A 1 91  ? 9.322   13.516  -10.727 1.000 16.706 0 106  TYR A CE2  1 ? 
ATOM   1444 C CZ   . TYR A 1 91  ? 10.093  12.559  -11.343 1.000 16.509 0 106  TYR A CZ   1 ? 
ATOM   1445 O OH   . TYR A 1 91  ? 10.875  11.771  -10.582 1.000 19.777 0 106  TYR A OH   1 ? 
ATOM   1446 H H    . TYR A 1 91  ? 8.520   17.520  -12.476 1.000 19.138 0 106  TYR A H    1 c 
ATOM   1447 H HA   . TYR A 1 91  ? 8.969   16.111  -14.869 1.000 19.586 0 106  TYR A HA   1 c 
ATOM   1448 H HB2  . TYR A 1 91  ? 6.830   15.468  -13.076 1.000 17.620 0 106  TYR A HB2  1 c 
ATOM   1449 H HB3  . TYR A 1 91  ? 7.194   14.677  -14.408 1.000 17.551 0 106  TYR A HB3  1 c 
ATOM   1450 H HD1  . TYR A 1 91  ? 9.206   13.183  -14.406 1.000 16.044 0 106  TYR A HD1  1 c 
ATOM   1451 H HD2  . TYR A 1 91  ? 7.992   14.990  -11.026 1.000 16.237 0 106  TYR A HD2  1 c 
ATOM   1452 H HE1  . TYR A 1 91  ? 10.567  11.783  -13.157 1.000 16.437 0 106  TYR A HE1  1 c 
ATOM   1453 H HE2  . TYR A 1 91  ? 9.344   13.600  -9.789  1.000 16.537 0 106  TYR A HE2  1 c 
ATOM   1454 H HH   . TYR A 1 91  ? 11.652  12.124  -10.497 0.000 19.770 0 106  TYR A HH   1 c 
ATOM   1455 N N    . PRO A 1 92  ? 7.694   18.393  -15.503 1.000 23.211 0 107  PRO A N    1 ? 
ATOM   1456 C CA   . PRO A 1 92  ? 6.738   19.348  -16.068 1.000 26.009 0 107  PRO A CA   1 ? 
ATOM   1457 C C    . PRO A 1 92  ? 5.710   18.613  -16.924 1.000 24.964 0 107  PRO A C    1 ? 
ATOM   1458 O O    . PRO A 1 92  ? 6.098   17.732  -17.697 1.000 23.999 0 107  PRO A O    1 ? 
ATOM   1459 C CB   . PRO A 1 92  ? 7.648   20.250  -16.918 1.000 27.890 0 107  PRO A CB   1 ? 
ATOM   1460 C CG   . PRO A 1 92  ? 9.011   20.181  -16.248 1.000 28.527 0 107  PRO A CG   1 ? 
ATOM   1461 C CD   . PRO A 1 92  ? 9.108   18.735  -15.766 1.000 26.189 0 107  PRO A CD   1 ? 
ATOM   1462 H HA   . PRO A 1 92  ? 6.301   19.870  -15.350 1.000 25.559 0 107  PRO A HA   1 c 
ATOM   1463 H HB2  . PRO A 1 92  ? 7.698   19.922  -17.847 1.000 27.565 0 107  PRO A HB2  1 c 
ATOM   1464 H HB3  . PRO A 1 92  ? 7.310   21.176  -16.929 1.000 27.593 0 107  PRO A HB3  1 c 
ATOM   1465 H HG2  . PRO A 1 92  ? 9.727   20.386  -16.886 1.000 27.850 0 107  PRO A HG2  1 c 
ATOM   1466 H HG3  . PRO A 1 92  ? 9.066   20.806  -15.496 1.000 27.878 0 107  PRO A HG3  1 c 
ATOM   1467 H HD2  . PRO A 1 92  ? 9.493   18.154  -16.459 1.000 25.932 0 107  PRO A HD2  1 c 
ATOM   1468 H HD3  . PRO A 1 92  ? 9.650   18.674  -14.952 1.000 25.833 0 107  PRO A HD3  1 c 
ATOM   1469 N N    A ARG A 1 93  ? 4.431   18.961  -16.779 0.500 25.208 0 108  ARG A N    1 ? 
ATOM   1470 N N    B ARG A 1 93  ? 4.417   18.941  -16.770 0.500 22.426 0 108  ARG A N    1 ? 
ATOM   1471 C CA   A ARG A 1 93  ? 3.400   18.310  -17.566 0.500 26.644 0 108  ARG A CA   1 ? 
ATOM   1472 C CA   B ARG A 1 93  ? 3.353   18.297  -17.536 0.500 22.091 0 108  ARG A CA   1 ? 
ATOM   1473 C C    A ARG A 1 93  ? 3.277   19.031  -18.902 0.500 27.559 0 108  ARG A C    1 ? 
ATOM   1474 C C    B ARG A 1 93  ? 3.224   18.984  -18.900 0.500 24.325 0 108  ARG A C    1 ? 
ATOM   1475 O O    A ARG A 1 93  ? 2.654   20.082  -19.007 0.500 29.580 0 108  ARG A O    1 ? 
ATOM   1476 O O    B ARG A 1 93  ? 2.493   19.960  -19.043 0.500 24.833 0 108  ARG A O    1 ? 
ATOM   1477 C CB   A ARG A 1 93  ? 2.088   18.184  -16.796 0.500 26.924 0 108  ARG A CB   1 ? 
ATOM   1478 C CB   B ARG A 1 93  ? 1.997   18.282  -16.810 0.500 20.284 0 108  ARG A CB   1 ? 
ATOM   1479 C CG   A ARG A 1 93  ? 2.245   17.037  -15.811 0.500 26.323 0 108  ARG A CG   1 ? 
ATOM   1480 C CG   B ARG A 1 93  ? 1.720   17.116  -15.860 0.500 18.272 0 108  ARG A CG   1 ? 
ATOM   1481 C CD   A ARG A 1 93  ? 0.951   16.796  -15.103 0.500 25.863 0 108  ARG A CD   1 ? 
ATOM   1482 C CD   B ARG A 1 93  ? 2.539   17.132  -14.581 0.500 16.776 0 108  ARG A CD   1 ? 
ATOM   1483 N NE   A ARG A 1 93  ? -0.038  15.953  -15.790 0.500 21.830 0 108  ARG A NE   1 ? 
ATOM   1484 N NE   B ARG A 1 93  ? 2.132   18.248  -13.719 0.500 17.581 0 108  ARG A NE   1 ? 
ATOM   1485 C CZ   A ARG A 1 93  ? -1.300  16.347  -15.857 0.500 20.283 0 108  ARG A CZ   1 ? 
ATOM   1486 C CZ   B ARG A 1 93  ? 2.974   19.026  -13.070 0.500 17.119 0 108  ARG A CZ   1 ? 
ATOM   1487 N NH1  A ARG A 1 93  ? -1.611  17.579  -15.487 0.500 21.589 0 108  ARG A NH1  1 ? 
ATOM   1488 N NH1  B ARG A 1 93  ? 4.265   18.799  -13.124 0.500 16.860 0 108  ARG A NH1  1 ? 
ATOM   1489 N NH2  A ARG A 1 93  ? -2.259  15.551  -16.254 0.500 14.805 0 108  ARG A NH2  1 ? 
ATOM   1490 N NH2  B ARG A 1 93  ? 2.518   20.048  -12.367 0.500 18.671 0 108  ARG A NH2  1 ? 
ATOM   1491 H H    A ARG A 1 93  ? 4.195   19.613  -16.183 0.500 25.469 0 108  ARG A H    1 c 
ATOM   1492 H H    B ARG A 1 93  ? 4.191   19.589  -16.166 0.500 22.970 0 108  ARG A H    1 c 
ATOM   1493 H HA   A ARG A 1 93  ? 3.700   17.384  -17.747 0.500 26.520 0 108  ARG A HA   1 c 
ATOM   1494 H HA   B ARG A 1 93  ? 3.613   17.354  -17.686 0.500 22.268 0 108  ARG A HA   1 c 
ATOM   1495 H HB2  A ARG A 1 93  ? 1.896   19.015  -16.313 0.500 26.724 0 108  ARG A HB2  1 c 
ATOM   1496 H HB2  B ARG A 1 93  ? 1.920   19.116  -16.299 0.500 20.193 0 108  ARG A HB2  1 c 
ATOM   1497 H HB3  A ARG A 1 93  ? 1.348   17.996  -17.412 0.500 26.724 0 108  ARG A HB3  1 c 
ATOM   1498 H HB3  B ARG A 1 93  ? 1.291   18.294  -17.491 0.500 20.193 0 108  ARG A HB3  1 c 
ATOM   1499 H HG2  A ARG A 1 93  ? 2.511   16.222  -16.291 0.500 26.350 0 108  ARG A HG2  1 c 
ATOM   1500 H HG2  B ARG A 1 93  ? 0.767   17.123  -15.622 0.500 18.348 0 108  ARG A HG2  1 c 
ATOM   1501 H HG3  A ARG A 1 93  ? 2.940   17.258  -15.153 0.500 26.350 0 108  ARG A HG3  1 c 
ATOM   1502 H HG3  B ARG A 1 93  ? 1.895   16.274  -16.334 0.500 18.348 0 108  ARG A HG3  1 c 
ATOM   1503 H HD2  A ARG A 1 93  ? 1.160   16.403  -14.236 0.500 24.700 0 108  ARG A HD2  1 c 
ATOM   1504 H HD2  B ARG A 1 93  ? 2.414   16.288  -14.100 0.500 17.295 0 108  ARG A HD2  1 c 
ATOM   1505 H HD3  A ARG A 1 93  ? 0.547   17.669  -14.933 0.500 24.964 0 108  ARG A HD3  1 c 
ATOM   1506 H HD3  B ARG A 1 93  ? 3.488   17.221  -14.801 0.500 17.308 0 108  ARG A HD3  1 c 
ATOM   1507 H HE   A ARG A 1 93  ? 0.207   15.198  -16.148 0.500 22.253 0 108  ARG A HE   1 c 
ATOM   1508 H HE   B ARG A 1 93  ? 1.281   18.409  -13.630 0.500 17.283 0 108  ARG A HE   1 c 
ATOM   1509 H HH11 A ARG A 1 93  ? -2.451  17.851  -15.528 0.500 21.179 0 108  ARG A HH11 1 c 
ATOM   1510 H HH11 B ARG A 1 93  ? 4.822   19.326  -12.684 0.500 16.939 0 108  ARG A HH11 1 c 
ATOM   1511 H HH12 A ARG A 1 93  ? -0.977  18.125  -15.200 0.500 21.179 0 108  ARG A HH12 1 c 
ATOM   1512 H HH12 B ARG A 1 93  ? 4.572   18.121  -13.600 0.500 16.939 0 108  ARG A HH12 1 c 
ATOM   1513 H HH21 A ARG A 1 93  ? -3.091  15.847  -16.285 0.500 16.318 0 108  ARG A HH21 1 c 
ATOM   1514 H HH21 B ARG A 1 93  ? 3.084   20.568  -11.932 0.500 18.179 0 108  ARG A HH21 1 c 
ATOM   1515 H HH22 A ARG A 1 93  ? -2.071  14.720  -16.489 0.500 16.318 0 108  ARG A HH22 1 c 
ATOM   1516 H HH22 B ARG A 1 93  ? 1.649   20.206  -12.336 0.500 18.179 0 108  ARG A HH22 1 c 
ATOM   1517 N N    . GLU A 1 94  ? 3.904   18.430  -19.914 1.000 28.389 0 109  GLU A N    1 ? 
ATOM   1518 C CA   . GLU A 1 94  ? 3.869   18.945  -21.272 1.000 31.006 0 109  GLU A CA   1 ? 
ATOM   1519 C C    . GLU A 1 94  ? 2.458   18.750  -21.825 1.000 35.257 0 109  GLU A C    1 ? 
ATOM   1520 O O    . GLU A 1 94  ? 1.956   17.626  -21.853 1.000 29.859 0 109  GLU A O    1 ? 
ATOM   1521 C CB   . GLU A 1 94  ? 4.900   18.163  -22.097 1.000 34.065 0 109  GLU A CB   1 ? 
ATOM   1522 C CG   . GLU A 1 94  ? 6.329   18.210  -21.555 1.000 36.642 0 109  GLU A CG   1 ? 
ATOM   1523 C CD   . GLU A 1 94  ? 7.153   19.400  -22.000 1.000 40.970 0 109  GLU A CD   1 ? 
ATOM   1524 O OE1  . GLU A 1 94  ? 6.870   19.949  -23.107 1.000 40.198 0 109  GLU A OE1  1 ? 
ATOM   1525 O OE2  . GLU A 1 94  ? 8.058   19.776  -21.214 1.000 40.645 0 109  GLU A OE2  1 ? 
ATOM   1526 H H    . GLU A 1 94  ? 4.390   17.673  -19.752 1.000 27.878 0 109  GLU A H    1 c 
ATOM   1527 H HA   . GLU A 1 94  ? 4.095   19.910  -21.258 1.000 31.715 0 109  GLU A HA   1 c 
ATOM   1528 H HB2  . GLU A 1 94  ? 4.621   17.225  -22.133 1.000 33.898 0 109  GLU A HB2  1 c 
ATOM   1529 H HB3  . GLU A 1 94  ? 4.893   18.508  -23.014 1.000 33.967 0 109  GLU A HB3  1 c 
ATOM   1530 H HG2  . GLU A 1 94  ? 6.301   18.207  -20.576 1.000 36.867 0 109  GLU A HG2  1 c 
ATOM   1531 H HG3  . GLU A 1 94  ? 6.797   17.394  -21.832 1.000 36.960 0 109  GLU A HG3  1 c 
ATOM   1532 N N    . GLY A 1 95  ? 1.788   19.846  -22.198 1.000 33.119 0 110  GLY A N    1 ? 
ATOM   1533 C CA   . GLY A 1 95  ? 0.452   19.759  -22.768 1.000 34.835 0 110  GLY A CA   1 ? 
ATOM   1534 C C    . GLY A 1 95  ? -0.621  19.304  -21.771 1.000 35.056 0 110  GLY A C    1 ? 
ATOM   1535 O O    . GLY A 1 95  ? -1.695  18.842  -22.161 1.000 34.407 0 110  GLY A O    1 ? 
ATOM   1536 H H    . GLY A 1 95  ? 2.172   20.669  -22.094 1.000 33.960 0 110  GLY A H    1 c 
ATOM   1537 H HA2  . GLY A 1 95  ? 0.204   20.644  -23.124 1.000 34.461 0 110  GLY A HA2  1 c 
ATOM   1538 H HA3  . GLY A 1 95  ? 0.474   19.130  -23.526 1.000 34.444 0 110  GLY A HA3  1 c 
ATOM   1539 N N    . GLY A 1 96  ? -0.355  19.408  -20.468 1.000 34.029 0 111  GLY A N    1 ? 
ATOM   1540 C CA   . GLY A 1 96  ? -1.381  19.052  -19.484 1.000 28.138 0 111  GLY A CA   1 ? 
ATOM   1541 C C    . GLY A 1 96  ? -1.601  17.528  -19.347 1.000 30.996 0 111  GLY A C    1 ? 
ATOM   1542 O O    . GLY A 1 96  ? -2.624  17.077  -18.823 1.000 35.981 0 111  GLY A O    1 ? 
ATOM   1543 H H    . GLY A 1 96  ? 0.458   19.709  -20.179 1.000 32.875 0 111  GLY A H    1 c 
ATOM   1544 H HA2  . GLY A 1 96  ? -1.117  19.420  -18.608 1.000 30.087 0 111  GLY A HA2  1 c 
ATOM   1545 H HA3  . GLY A 1 96  ? -2.231  19.481  -19.742 1.000 30.123 0 111  GLY A HA3  1 c 
ATOM   1546 N N    . VAL A 1 97  ? -0.639  16.737  -19.833 1.000 21.949 0 112  VAL A N    1 ? 
ATOM   1547 C CA   . VAL A 1 97  ? -0.628  15.285  -19.650 1.000 18.583 0 112  VAL A CA   1 ? 
ATOM   1548 C C    . VAL A 1 97  ? 0.698   14.869  -19.017 1.000 15.654 0 112  VAL A C    1 ? 
ATOM   1549 O O    . VAL A 1 97  ? 1.696   15.595  -19.030 1.000 16.277 0 112  VAL A O    1 ? 
ATOM   1550 C CB   . VAL A 1 97  ? -0.896  14.541  -20.959 1.000 20.748 0 112  VAL A CB   1 ? 
ATOM   1551 C CG1  . VAL A 1 97  ? -2.249  14.921  -21.544 1.000 24.435 0 112  VAL A CG1  1 ? 
ATOM   1552 C CG2  . VAL A 1 97  ? 0.241   14.749  -21.947 1.000 20.120 0 112  VAL A CG2  1 ? 
ATOM   1553 H H    . VAL A 1 97  ? 0.054   17.116  -20.292 1.000 23.092 0 112  VAL A H    1 c 
ATOM   1554 H HA   . VAL A 1 97  ? -1.342  15.055  -19.024 1.000 19.107 0 112  VAL A HA   1 c 
ATOM   1555 H HB   . VAL A 1 97  ? -0.928  13.580  -20.743 1.000 20.771 0 112  VAL A HB   1 c 
ATOM   1556 H HG11 . VAL A 1 97  ? -2.263  15.872  -21.742 1.000 23.314 0 112  VAL A HG11 1 c 
ATOM   1557 H HG12 . VAL A 1 97  ? -2.949  14.714  -20.902 1.000 23.379 0 112  VAL A HG12 1 c 
ATOM   1558 H HG13 . VAL A 1 97  ? -2.400  14.419  -22.362 1.000 23.381 0 112  VAL A HG13 1 c 
ATOM   1559 H HG21 . VAL A 1 97  ? 0.039   14.281  -22.775 1.000 20.314 0 112  VAL A HG21 1 c 
ATOM   1560 H HG22 . VAL A 1 97  ? 1.068   14.400  -21.575 1.000 20.291 0 112  VAL A HG22 1 c 
ATOM   1561 H HG23 . VAL A 1 97  ? 0.343   15.697  -22.131 1.000 20.371 0 112  VAL A HG23 1 c 
ATOM   1562 N N    . SER A 1 98  ? 0.735   13.615  -18.523 1.000 12.311 0 113  SER A N    1 ? 
ATOM   1563 C CA   . SER A 1 98  ? 1.806   13.120  -17.712 1.000 11.853 0 113  SER A CA   1 ? 
ATOM   1564 C C    . SER A 1 98  ? 2.893   12.474  -18.573 1.000 10.580 0 113  SER A C    1 ? 
ATOM   1565 O O    . SER A 1 98  ? 2.629   12.061  -19.711 1.000 12.853 0 113  SER A O    1 ? 
ATOM   1566 C CB   . SER A 1 98  ? 1.244   12.094  -16.761 1.000 11.579 0 113  SER A CB   1 ? 
ATOM   1567 O OG   . SER A 1 98  ? 0.261   12.683  -15.923 1.000 12.681 0 113  SER A OG   1 ? 
ATOM   1568 H H    . SER A 1 98  ? 0.047   13.047  -18.722 1.000 13.012 0 113  SER A H    1 c 
ATOM   1569 H HA   . SER A 1 98  ? 2.198   13.869  -17.194 1.000 11.682 0 113  SER A HA   1 c 
ATOM   1570 H HB2  . SER A 1 98  ? 0.845   11.363  -17.270 1.000 11.900 0 113  SER A HB2  1 c 
ATOM   1571 H HB3  . SER A 1 98  ? 1.965   11.729  -16.213 1.000 11.889 0 113  SER A HB3  1 c 
ATOM   1572 H HG   . SER A 1 98  ? -0.038  12.089  -15.400 0.000 12.700 0 113  SER A HG   1 c 
ATOM   1573 N N    . SER A 1 99  ? 4.088   12.349  -18.027 1.000 10.876 0 114  SER A N    1 ? 
ATOM   1574 C CA   . SER A 1 99  ? 5.227   11.729  -18.690 1.000 10.797 0 114  SER A CA   1 ? 
ATOM   1575 C C    . SER A 1 99  ? 5.463   10.320  -18.165 1.000 10.737 0 114  SER A C    1 ? 
ATOM   1576 O O    . SER A 1 99  ? 5.106   9.974   -17.016 1.000 10.275 0 114  SER A O    1 ? 
ATOM   1577 C CB   . SER A 1 99  ? 6.455   12.539  -18.502 1.000 11.755 0 114  SER A CB   1 ? 
ATOM   1578 O OG   . SER A 1 99  ? 6.821   12.632  -17.136 1.000 11.920 0 114  SER A OG   1 ? 
ATOM   1579 H H    . SER A 1 99  ? 4.209   12.670  -17.180 1.000 10.801 0 114  SER A H    1 c 
ATOM   1580 H HA   . SER A 1 99  ? 5.032   11.673  -19.656 1.000 10.975 0 114  SER A HA   1 c 
ATOM   1581 H HB2  . SER A 1 99  ? 7.186   12.135  -19.006 1.000 11.569 0 114  SER A HB2  1 c 
ATOM   1582 H HB3  . SER A 1 99  ? 6.305   13.436  -18.857 1.000 11.566 0 114  SER A HB3  1 c 
ATOM   1583 H HG   . SER A 1 99  ? 7.523   13.100  -17.077 0.000 11.910 0 114  SER A HG   1 c 
ATOM   1584 N N    . ARG A 1 100 ? 6.168   9.512   -18.938 1.000 9.399  0 115  ARG A N    1 ? 
ATOM   1585 C CA   . ARG A 1 100 ? 6.504   8.175   -18.503 1.000 8.838  0 115  ARG A CA   1 ? 
ATOM   1586 C C    . ARG A 1 100 ? 7.323   8.226   -17.221 1.000 9.847  0 115  ARG A C    1 ? 
ATOM   1587 O O    . ARG A 1 100 ? 7.184   7.370   -16.337 1.000 9.893  0 115  ARG A O    1 ? 
ATOM   1588 C CB   . ARG A 1 100 ? 7.220   7.422   -19.619 1.000 9.371  0 115  ARG A CB   1 ? 
ATOM   1589 C CG   . ARG A 1 100 ? 7.503   5.966   -19.304 1.000 8.811  0 115  ARG A CG   1 ? 
ATOM   1590 C CD   . ARG A 1 100 ? 7.981   5.181   -20.531 1.000 8.779  0 115  ARG A CD   1 ? 
ATOM   1591 N NE   . ARG A 1 100 ? 6.955   5.107   -21.561 1.000 8.135  0 115  ARG A NE   1 ? 
ATOM   1592 C CZ   . ARG A 1 100 ? 5.919   4.284   -21.560 1.000 8.267  0 115  ARG A CZ   1 ? 
ATOM   1593 N NH1  . ARG A 1 100 ? 5.903   3.223   -20.735 1.000 8.812  0 115  ARG A NH1  1 ? 
ATOM   1594 N NH2  . ARG A 1 100 ? 4.934   4.458   -22.395 1.000 8.665  0 115  ARG A NH2  1 ? 
ATOM   1595 H H    . ARG A 1 100 ? 6.451   9.798   -19.759 1.000 9.585  0 115  ARG A H    1 c 
ATOM   1596 H HA   . ARG A 1 100 ? 5.658   7.697   -18.309 1.000 9.235  0 115  ARG A HA   1 c 
ATOM   1597 H HB2  . ARG A 1 100 ? 6.670   7.468   -20.430 1.000 9.109  0 115  ARG A HB2  1 c 
ATOM   1598 H HB3  . ARG A 1 100 ? 8.069   7.874   -19.808 1.000 9.116  0 115  ARG A HB3  1 c 
ATOM   1599 H HG2  . ARG A 1 100 ? 8.191   5.914   -18.605 1.000 8.946  0 115  ARG A HG2  1 c 
ATOM   1600 H HG3  . ARG A 1 100 ? 6.686   5.547   -18.955 1.000 8.998  0 115  ARG A HG3  1 c 
ATOM   1601 H HD2  . ARG A 1 100 ? 8.774   5.621   -20.900 1.000 8.632  0 115  ARG A HD2  1 c 
ATOM   1602 H HD3  . ARG A 1 100 ? 8.238   4.278   -20.261 1.000 8.652  0 115  ARG A HD3  1 c 
ATOM   1603 H HE   . ARG A 1 100 ? 7.030   5.650   -22.239 1.000 8.317  0 115  ARG A HE   1 c 
ATOM   1604 H HH11 . ARG A 1 100 ? 5.152   3.012   -20.312 1.000 8.646  0 115  ARG A HH11 1 c 
ATOM   1605 H HH12 . ARG A 1 100 ? 6.634   2.735   -20.625 1.000 8.643  0 115  ARG A HH12 1 c 
ATOM   1606 H HH21 . ARG A 1 100 ? 4.270   3.874   -22.416 1.000 8.542  0 115  ARG A HH21 1 c 
ATOM   1607 H HH22 . ARG A 1 100 ? 4.930   5.156   -22.937 1.000 8.536  0 115  ARG A HH22 1 c 
ATOM   1608 N N    . GLU A 1 101 ? 8.239   9.185   -17.127 1.000 9.947  0 116  GLU A N    1 ? 
ATOM   1609 C CA   . GLU A 1 101 ? 9.100   9.313   -15.949 1.000 10.536 0 116  GLU A CA   1 ? 
ATOM   1610 C C    . GLU A 1 101 ? 8.269   9.590   -14.688 1.000 10.092 0 116  GLU A C    1 ? 
ATOM   1611 O O    . GLU A 1 101 ? 8.595   9.065   -13.602 1.000 11.003 0 116  GLU A O    1 ? 
ATOM   1612 C CB   . GLU A 1 101 ? 10.185  10.390  -16.108 1.000 12.918 0 116  GLU A CB   1 ? 
ATOM   1613 C CG   . GLU A 1 101 ? 11.167  10.206  -17.252 1.000 15.691 0 116  GLU A CG   1 ? 
ATOM   1614 C CD   . GLU A 1 101 ? 10.670  10.694  -18.582 1.000 15.074 0 116  GLU A CD   1 ? 
ATOM   1615 O OE1  . GLU A 1 101 ? 9.544   11.126  -18.782 1.000 13.222 0 116  GLU A OE1  1 ? 
ATOM   1616 O OE2  . GLU A 1 101 ? 11.521  10.520  -19.517 1.000 20.557 0 116  GLU A OE2  1 ? 
ATOM   1617 H H    . GLU A 1 101 ? 8.334   9.784   -17.810 1.000 10.084 0 116  GLU A H    1 c 
ATOM   1618 H HA   . GLU A 1 101 ? 9.564   8.447   -15.821 1.000 10.729 0 116  GLU A HA   1 c 
ATOM   1619 H HB2  . GLU A 1 101 ? 9.746   11.259  -16.216 1.000 12.910 0 116  GLU A HB2  1 c 
ATOM   1620 H HB3  . GLU A 1 101 ? 10.704  10.426  -15.277 1.000 12.889 0 116  GLU A HB3  1 c 
ATOM   1621 H HG2  . GLU A 1 101 ? 11.995  10.686  -17.037 1.000 14.872 0 116  GLU A HG2  1 c 
ATOM   1622 H HG3  . GLU A 1 101 ? 11.389  9.254   -17.333 1.000 14.873 0 116  GLU A HG3  1 c 
ATOM   1623 N N    . LEU A 1 102 ? 7.263   10.415  -14.803 1.000 9.872  0 117  LEU A N    1 ? 
ATOM   1624 C CA   . LEU A 1 102 ? 6.419   10.744  -13.650 1.000 9.732  0 117  LEU A CA   1 ? 
ATOM   1625 C C    . LEU A 1 102 ? 5.649   9.505   -13.232 1.000 10.081 0 117  LEU A C    1 ? 
ATOM   1626 O O    . LEU A 1 102 ? 5.548   9.203   -12.032 1.000 10.454 0 117  LEU A O    1 ? 
ATOM   1627 C CB   . LEU A 1 102 ? 5.527   11.903  -14.058 1.000 9.973  0 117  LEU A CB   1 ? 
ATOM   1628 C CG   . LEU A 1 102 ? 4.480   12.355  -13.029 1.000 10.706 0 117  LEU A CG   1 ? 
ATOM   1629 C CD1  . LEU A 1 102 ? 5.075   12.622  -11.651 1.000 12.600 0 117  LEU A CD1  1 ? 
ATOM   1630 C CD2  . LEU A 1 102 ? 3.763   13.605  -13.508 1.000 11.005 0 117  LEU A CD2  1 ? 
ATOM   1631 H H    . LEU A 1 102 ? 7.082   10.802  -15.611 1.000 9.899  0 117  LEU A H    1 c 
ATOM   1632 H HA   . LEU A 1 102 ? 7.004   11.027  -12.902 1.000 9.896  0 117  LEU A HA   1 c 
ATOM   1633 H HB2  . LEU A 1 102 ? 6.103   12.672  -14.272 1.000 10.119 0 117  LEU A HB2  1 c 
ATOM   1634 H HB3  . LEU A 1 102 ? 5.056   11.650  -14.885 1.000 10.085 0 117  LEU A HB3  1 c 
ATOM   1635 H HG   . LEU A 1 102 ? 3.806   11.634  -12.936 1.000 10.946 0 117  LEU A HG   1 c 
ATOM   1636 H HD11 . LEU A 1 102 ? 5.410   11.792  -11.274 1.000 11.970 0 117  LEU A HD11 1 c 
ATOM   1637 H HD12 . LEU A 1 102 ? 4.390   12.989  -11.067 1.000 11.987 0 117  LEU A HD12 1 c 
ATOM   1638 H HD13 . LEU A 1 102 ? 5.806   13.258  -11.731 1.000 11.998 0 117  LEU A HD13 1 c 
ATOM   1639 H HD21 . LEU A 1 102 ? 3.322   13.422  -14.355 1.000 10.923 0 117  LEU A HD21 1 c 
ATOM   1640 H HD22 . LEU A 1 102 ? 4.407   14.323  -13.629 1.000 10.923 0 117  LEU A HD22 1 c 
ATOM   1641 H HD23 . LEU A 1 102 ? 3.100   13.873  -12.850 1.000 10.945 0 117  LEU A HD23 1 c 
ATOM   1642 N N    . VAL A 1 103 ? 5.024   8.779   -14.181 1.000 10.026 0 118  VAL A N    1 ? 
ATOM   1643 C CA   . VAL A 1 103 ? 4.321   7.552   -13.856 1.000 9.487  0 118  VAL A CA   1 ? 
ATOM   1644 C C    . VAL A 1 103 ? 5.239   6.552   -13.162 1.000 9.949  0 118  VAL A C    1 ? 
ATOM   1645 O O    . VAL A 1 103 ? 4.860   5.932   -12.153 1.000 10.250 0 118  VAL A O    1 ? 
ATOM   1646 C CB   . VAL A 1 103 ? 3.676   6.950   -15.118 1.000 9.700  0 118  VAL A CB   1 ? 
ATOM   1647 C CG1  . VAL A 1 103 ? 3.110   5.562   -14.829 1.000 10.477 0 118  VAL A CG1  1 ? 
ATOM   1648 C CG2  . VAL A 1 103 ? 2.619   7.866   -15.682 1.000 9.928  0 118  VAL A CG2  1 ? 
ATOM   1649 H H    . VAL A 1 103 ? 5.048   9.061   -15.050 1.000 9.912  0 118  VAL A H    1 c 
ATOM   1650 H HA   . VAL A 1 103 ? 3.603   7.779   -13.234 1.000 9.717  0 118  VAL A HA   1 c 
ATOM   1651 H HB   . VAL A 1 103 ? 4.388   6.855   -15.794 1.000 9.842  0 118  VAL A HB   1 c 
ATOM   1652 H HG11 . VAL A 1 103 ? 2.603   5.584   -14.000 1.000 10.241 0 118  VAL A HG11 1 c 
ATOM   1653 H HG12 . VAL A 1 103 ? 3.838   4.923   -14.747 1.000 10.241 0 118  VAL A HG12 1 c 
ATOM   1654 H HG13 . VAL A 1 103 ? 2.526   5.291   -15.558 1.000 10.243 0 118  VAL A HG13 1 c 
ATOM   1655 H HG21 . VAL A 1 103 ? 2.191   7.439   -16.443 1.000 9.863  0 118  VAL A HG21 1 c 
ATOM   1656 H HG22 . VAL A 1 103 ? 3.026   8.700   -15.967 1.000 9.863  0 118  VAL A HG22 1 c 
ATOM   1657 H HG23 . VAL A 1 103 ? 1.951   8.050   -14.999 1.000 9.861  0 118  VAL A HG23 1 c 
ATOM   1658 N N    A LYS A 1 104 ? 6.472   6.373   -13.633 0.500 10.856 0 119  LYS A N    1 ? 
ATOM   1659 N N    B LYS A 1 104 ? 6.432   6.351   -13.708 0.500 10.395 0 119  LYS A N    1 ? 
ATOM   1660 C CA   A LYS A 1 104 ? 7.410   5.437   -13.018 0.500 11.985 0 119  LYS A CA   1 ? 
ATOM   1661 C CA   B LYS A 1 104 ? 7.442   5.513   -13.084 0.500 11.272 0 119  LYS A CA   1 ? 
ATOM   1662 C C    A LYS A 1 104 ? 7.874   5.937   -11.635 0.500 11.446 0 119  LYS A C    1 ? 
ATOM   1663 C C    B LYS A 1 104 ? 7.677   5.944   -11.635 0.500 10.521 0 119  LYS A C    1 ? 
ATOM   1664 O O    A LYS A 1 104 ? 8.195   5.108   -10.755 0.500 10.701 0 119  LYS A O    1 ? 
ATOM   1665 O O    B LYS A 1 104 ? 7.706   5.076   -10.748 0.500 9.940  0 119  LYS A O    1 ? 
ATOM   1666 C CB   A LYS A 1 104 ? 8.549   5.138   -14.015 0.500 13.737 0 119  LYS A CB   1 ? 
ATOM   1667 C CB   B LYS A 1 104 ? 8.770   5.509   -13.865 0.500 12.836 0 119  LYS A CB   1 ? 
ATOM   1668 C CG   A LYS A 1 104 ? 9.556   4.088   -13.559 0.500 15.138 0 119  LYS A CG   1 ? 
ATOM   1669 C CG   B LYS A 1 104 ? 9.783   4.542   -13.279 0.500 13.055 0 119  LYS A CG   1 ? 
ATOM   1670 C CD   A LYS A 1 104 ? 8.986   2.687   -13.295 0.500 16.978 0 119  LYS A CD   1 ? 
ATOM   1671 C CD   B LYS A 1 104 ? 9.285   3.113   -13.008 0.500 14.093 0 119  LYS A CD   1 ? 
ATOM   1672 C CE   A LYS A 1 104 ? 9.988   1.683   -12.798 0.500 19.021 0 119  LYS A CE   1 ? 
ATOM   1673 C CE   B LYS A 1 104 ? 10.337  2.027   -13.058 0.500 13.853 0 119  LYS A CE   1 ? 
ATOM   1674 N NZ   A LYS A 1 104 ? 10.924  1.174   -13.791 0.500 21.248 0 119  LYS A NZ   1 ? 
ATOM   1675 N NZ   B LYS A 1 104 ? 11.379  2.220   -12.032 0.500 14.190 0 119  LYS A NZ   1 ? 
ATOM   1676 H H    A LYS A 1 104 ? 6.743   6.845   -14.367 0.500 10.856 0 119  LYS A H    1 c 
ATOM   1677 H H    B LYS A 1 104 ? 6.627   6.748   -14.508 0.500 10.467 0 119  LYS A H    1 c 
ATOM   1678 H HA   A LYS A 1 104 ? 6.928   4.584   -12.874 0.500 11.997 0 119  LYS A HA   1 c 
ATOM   1679 H HA   B LYS A 1 104 ? 7.099   4.586   -13.071 0.500 11.287 0 119  LYS A HA   1 c 
ATOM   1680 H HB2  A LYS A 1 104 ? 8.156   4.837   -14.859 0.500 13.721 0 119  LYS A HB2  1 c 
ATOM   1681 H HB2  B LYS A 1 104 ? 8.599   5.261   -14.797 0.500 12.592 0 119  LYS A HB2  1 c 
ATOM   1682 H HB3  A LYS A 1 104 ? 9.033   5.972   -14.195 0.500 13.641 0 119  LYS A HB3  1 c 
ATOM   1683 H HB3  B LYS A 1 104 ? 9.153   6.412   -13.856 0.500 12.556 0 119  LYS A HB3  1 c 
ATOM   1684 H HG2  A LYS A 1 104 ? 10.256  4.017   -14.244 0.500 15.194 0 119  LYS A HG2  1 c 
ATOM   1685 H HG2  B LYS A 1 104 ? 10.546  4.493   -13.894 0.500 13.306 0 119  LYS A HG2  1 c 
ATOM   1686 H HG3  A LYS A 1 104 ? 9.985   4.412   -12.737 0.500 15.194 0 119  LYS A HG3  1 c 
ATOM   1687 H HG3  B LYS A 1 104 ? 10.115  4.921   -12.436 0.500 13.245 0 119  LYS A HG3  1 c 
ATOM   1688 H HD2  A LYS A 1 104 ? 8.262   2.762   -12.636 0.500 16.992 0 119  LYS A HD2  1 c 
ATOM   1689 H HD2  B LYS A 1 104 ? 8.861   3.098   -12.123 0.500 13.807 0 119  LYS A HD2  1 c 
ATOM   1690 H HD3  A LYS A 1 104 ? 8.593   2.350   -14.128 0.500 17.017 0 119  LYS A HD3  1 c 
ATOM   1691 H HD3  B LYS A 1 104 ? 8.588   2.902   -13.666 0.500 13.851 0 119  LYS A HD3  1 c 
ATOM   1692 H HE2  A LYS A 1 104 ? 10.502  2.092   -12.079 0.500 18.989 0 119  LYS A HE2  1 c 
ATOM   1693 H HE2  B LYS A 1 104 ? 9.914   1.161   -12.918 0.500 13.998 0 119  LYS A HE2  1 c 
ATOM   1694 H HE3  A LYS A 1 104 ? 9.506   0.928   -12.417 0.500 19.018 0 119  LYS A HE3  1 c 
ATOM   1695 H HE3  B LYS A 1 104 ? 10.756  2.020   -13.936 0.500 14.049 0 119  LYS A HE3  1 c 
ATOM   1696 H HZ1  A LYS A 1 104 ? 11.547  1.807   -13.974 0.500 20.528 0 119  LYS A HZ1  1 c 
ATOM   1697 H HZ1  B LYS A 1 104 ? 11.059  1.974   -11.221 0.500 14.079 0 119  LYS A HZ1  1 c 
ATOM   1698 H HZ2  A LYS A 1 104 ? 10.483  0.966   -14.553 0.500 20.504 0 119  LYS A HZ2  1 c 
ATOM   1699 H HZ2  B LYS A 1 104 ? 11.625  3.092   -12.004 0.500 14.084 0 119  LYS A HZ2  1 c 
ATOM   1700 H HZ3  A LYS A 1 104 ? 11.338  0.433   -13.471 0.500 20.528 0 119  LYS A HZ3  1 c 
ATOM   1701 H HZ3  B LYS A 1 104 ? 12.103  1.712   -12.232 0.500 14.084 0 119  LYS A HZ3  1 c 
ATOM   1702 N N    A LYS A 1 105 ? 7.927   7.264   -11.439 0.500 11.416 0 120  LYS A N    1 ? 
ATOM   1703 N N    B LYS A 1 105 ? 7.902   7.240   -11.406 0.500 10.774 0 120  LYS A N    1 ? 
ATOM   1704 C CA   A LYS A 1 105 ? 8.204   7.802   -10.118 0.500 10.884 0 120  LYS A CA   1 ? 
ATOM   1705 C CA   B LYS A 1 105 ? 8.249   7.671   -10.066 0.500 10.167 0 120  LYS A CA   1 ? 
ATOM   1706 C C    A LYS A 1 105 ? 7.114   7.361   -9.147  0.500 10.613 0 120  LYS A C    1 ? 
ATOM   1707 C C    B LYS A 1 105 ? 7.098   7.407   -9.101  0.500 10.228 0 120  LYS A C    1 ? 
ATOM   1708 O O    A LYS A 1 105 ? 7.415   6.820   -8.075  0.500 10.602 0 120  LYS A O    1 ? 
ATOM   1709 O O    B LYS A 1 105 ? 7.328   7.035   -7.959  0.500 9.919  0 120  LYS A O    1 ? 
ATOM   1710 C CB   A LYS A 1 105 ? 8.321   9.328   -10.149 0.500 10.799 0 120  LYS A CB   1 ? 
ATOM   1711 C CB   B LYS A 1 105 ? 8.661   9.140   -10.084 0.500 10.125 0 120  LYS A CB   1 ? 
ATOM   1712 C CG   A LYS A 1 105 ? 8.535   9.972   -8.796  0.500 11.671 0 120  LYS A CG   1 ? 
ATOM   1713 C CG   B LYS A 1 105 ? 8.992   9.693   -8.720  0.500 10.785 0 120  LYS A CG   1 ? 
ATOM   1714 C CD   A LYS A 1 105 ? 9.807   9.512   -8.094  0.500 12.982 0 120  LYS A CD   1 ? 
ATOM   1715 C CD   B LYS A 1 105 ? 10.226  9.097   -8.056  0.500 11.572 0 120  LYS A CD   1 ? 
ATOM   1716 C CE   A LYS A 1 105 ? 9.953   10.188  -6.763  0.500 15.146 0 120  LYS A CE   1 ? 
ATOM   1717 C CE   B LYS A 1 105 ? 10.628  9.905   -6.858  0.500 13.457 0 120  LYS A CE   1 ? 
ATOM   1718 N NZ   A LYS A 1 105 ? 10.701  9.423   -5.760  0.500 18.843 0 120  LYS A NZ   1 ? 
ATOM   1719 N NZ   B LYS A 1 105 ? 11.689  9.213   -6.119  0.500 14.525 0 120  LYS A NZ   1 ? 
ATOM   1720 H H    A LYS A 1 105 ? 7.789   7.837   -12.137 0.500 11.295 0 120  LYS A H    1 c 
ATOM   1721 H H    B LYS A 1 105 ? 7.840   7.854   -12.081 0.500 10.575 0 120  LYS A H    1 c 
ATOM   1722 H HA   A LYS A 1 105 ? 9.068   7.428   -9.809  0.500 10.920 0 120  LYS A HA   1 c 
ATOM   1723 H HA   B LYS A 1 105 ? 9.030   7.139   -9.768  0.500 10.286 0 120  LYS A HA   1 c 
ATOM   1724 H HB2  A LYS A 1 105 ? 9.070   9.575   -10.732 0.500 11.013 0 120  LYS A HB2  1 c 
ATOM   1725 H HB2  B LYS A 1 105 ? 9.447   9.244   -10.662 0.500 10.283 0 120  LYS A HB2  1 c 
ATOM   1726 H HB3  A LYS A 1 105 ? 7.503   9.700   -10.541 0.500 11.011 0 120  LYS A HB3  1 c 
ATOM   1727 H HB3  B LYS A 1 105 ? 7.932   9.671   -10.469 0.500 10.283 0 120  LYS A HB3  1 c 
ATOM   1728 H HG2  A LYS A 1 105 ? 8.570   10.946  -8.915  0.500 11.745 0 120  LYS A HG2  1 c 
ATOM   1729 H HG2  B LYS A 1 105 ? 9.117   10.664  -8.804  0.500 10.800 0 120  LYS A HG2  1 c 
ATOM   1730 H HG3  A LYS A 1 105 ? 7.763   9.766   -8.226  0.500 11.745 0 120  LYS A HG3  1 c 
ATOM   1731 H HG3  B LYS A 1 105 ? 8.217   9.548   -8.134  0.500 10.800 0 120  LYS A HG3  1 c 
ATOM   1732 H HD2  A LYS A 1 105 ? 9.775   8.539   -7.963  0.500 13.134 0 120  LYS A HD2  1 c 
ATOM   1733 H HD2  B LYS A 1 105 ? 10.034  8.176   -7.777  0.500 11.815 0 120  LYS A HD2  1 c 
ATOM   1734 H HD3  A LYS A 1 105 ? 10.585  9.726   -8.654  0.500 13.134 0 120  LYS A HD3  1 c 
ATOM   1735 H HD3  B LYS A 1 105 ? 10.967  9.081   -8.700  0.500 11.902 0 120  LYS A HD3  1 c 
ATOM   1736 H HE2  A LYS A 1 105 ? 10.398  11.042  -6.893  0.500 15.508 0 120  LYS A HE2  1 c 
ATOM   1737 H HE2  B LYS A 1 105 ? 10.947  10.780  -7.135  0.500 13.343 0 120  LYS A HE2  1 c 
ATOM   1738 H HE3  A LYS A 1 105 ? 9.063   10.369  -6.413  0.500 15.419 0 120  LYS A HE3  1 c 
ATOM   1739 H HE3  B LYS A 1 105 ? 9.859   10.029  -6.272  0.500 13.258 0 120  LYS A HE3  1 c 
ATOM   1740 H HZ1  A LYS A 1 105 ? 11.540  9.262   -6.061  0.500 17.616 0 120  LYS A HZ1  1 c 
ATOM   1741 H HZ1  B LYS A 1 105 ? 12.411  9.099   -6.654  0.500 14.187 0 120  LYS A HZ1  1 c 
ATOM   1742 H HZ2  A LYS A 1 105 ? 10.284  8.634   -5.603  0.500 17.616 0 120  LYS A HZ2  1 c 
ATOM   1743 H HZ2  B LYS A 1 105 ? 11.392  8.403   -5.843  0.500 14.187 0 120  LYS A HZ2  1 c 
ATOM   1744 H HZ3  A LYS A 1 105 ? 10.747  9.894   -4.987  0.500 17.616 0 120  LYS A HZ3  1 c 
ATOM   1745 H HZ3  B LYS A 1 105 ? 11.929  9.704   -5.396  0.500 14.187 0 120  LYS A HZ3  1 c 
ATOM   1746 N N    . VAL A 1 106 ? 5.858   7.598   -9.525  1.000 10.157 0 121  VAL A N    1 ? 
ATOM   1747 C CA   . VAL A 1 106 ? 4.736   7.290   -8.635  1.000 9.950  0 121  VAL A CA   1 ? 
ATOM   1748 C C    . VAL A 1 106 ? 4.738   5.791   -8.317  1.000 10.389 0 121  VAL A C    1 ? 
ATOM   1749 O O    . VAL A 1 106 ? 4.537   5.384   -7.167  1.000 10.050 0 121  VAL A O    1 ? 
ATOM   1750 C CB   . VAL A 1 106 ? 3.406   7.775   -9.197  1.000 9.687  0 121  VAL A CB   1 ? 
ATOM   1751 C CG1  . VAL A 1 106 ? 2.273   7.363   -8.273  1.000 10.241 0 121  VAL A CG1  1 ? 
ATOM   1752 C CG2  . VAL A 1 106 ? 3.420   9.282   -9.373  1.000 10.141 0 121  VAL A CG2  1 ? 
ATOM   1753 H H    . VAL A 1 106 ? 5.696   7.940   -10.358 1.000 10.227 0 121  VAL A H    1 c 
ATOM   1754 H HA   . VAL A 1 106 ? 4.888   7.769   -7.796  1.000 10.025 0 121  VAL A HA   1 c 
ATOM   1755 H HB   . VAL A 1 106 ? 3.277   7.348   -10.076 1.000 9.920  0 121  VAL A HB   1 c 
ATOM   1756 H HG11 . VAL A 1 106 ? 2.512   7.570   -7.353  1.000 10.074 0 121  VAL A HG11 1 c 
ATOM   1757 H HG12 . VAL A 1 106 ? 2.112   6.408   -8.358  1.000 10.076 0 121  VAL A HG12 1 c 
ATOM   1758 H HG13 . VAL A 1 106 ? 1.466   7.849   -8.513  1.000 10.074 0 121  VAL A HG13 1 c 
ATOM   1759 H HG21 . VAL A 1 106 ? 2.556   9.578   -9.703  1.000 10.006 0 121  VAL A HG21 1 c 
ATOM   1760 H HG22 . VAL A 1 106 ? 4.110   9.531   -10.008 1.000 10.010 0 121  VAL A HG22 1 c 
ATOM   1761 H HG23 . VAL A 1 106 ? 3.601   9.707   -8.518  1.000 10.006 0 121  VAL A HG23 1 c 
ATOM   1762 N N    A SER A 1 107 ? 4.928   4.938   -9.339  0.500 8.909  0 122  SER A N    1 ? 
ATOM   1763 N N    B SER A 1 107 ? 4.978   4.944   -9.323  0.500 10.720 0 122  SER A N    1 ? 
ATOM   1764 C CA   A SER A 1 107 ? 5.029   3.498   -9.159  0.500 8.483  0 122  SER A CA   1 ? 
ATOM   1765 C CA   B SER A 1 107 ? 5.027   3.507   -9.122  0.500 11.643 0 122  SER A CA   1 ? 
ATOM   1766 C C    A SER A 1 107 ? 6.117   3.158   -8.145  0.500 9.423  0 122  SER A C    1 ? 
ATOM   1767 C C    B SER A 1 107 ? 6.137   3.131   -8.147  0.500 11.225 0 122  SER A C    1 ? 
ATOM   1768 O O    A SER A 1 107 ? 5.882   2.374   -7.236  0.500 9.257  0 122  SER A O    1 ? 
ATOM   1769 O O    B SER A 1 107 ? 5.954   2.279   -7.287  0.500 11.101 0 122  SER A O    1 ? 
ATOM   1770 C CB   A SER A 1 107 ? 5.283   2.780   -10.506 0.500 7.924  0 122  SER A CB   1 ? 
ATOM   1771 C CB   B SER A 1 107 ? 5.220   2.805   -10.443 0.500 13.673 0 122  SER A CB   1 ? 
ATOM   1772 O OG   A SER A 1 107 ? 5.473   1.374   -10.352 0.500 6.621  0 122  SER A OG   1 ? 
ATOM   1773 O OG   B SER A 1 107 ? 4.335   3.360   -11.396 0.500 16.952 0 122  SER A OG   1 ? 
ATOM   1774 H H    A SER A 1 107 ? 4.992   5.275   -10.186 0.500 9.151  0 122  SER A H    1 c 
ATOM   1775 H H    B SER A 1 107 ? 5.110   5.273   -10.166 0.500 10.830 0 122  SER A H    1 c 
ATOM   1776 H HA   A SER A 1 107 ? 4.165   3.176   -8.798  0.500 8.630  0 122  SER A HA   1 c 
ATOM   1777 H HA   B SER A 1 107 ? 4.163   3.218   -8.735  0.500 11.683 0 122  SER A HA   1 c 
ATOM   1778 H HB2  A SER A 1 107 ? 4.523   2.938   -11.099 0.500 7.705  0 122  SER A HB2  1 c 
ATOM   1779 H HB2  B SER A 1 107 ? 6.142   2.917   -10.743 0.500 13.880 0 122  SER A HB2  1 c 
ATOM   1780 H HB3  A SER A 1 107 ? 6.074   3.166   -10.928 0.500 7.705  0 122  SER A HB3  1 c 
ATOM   1781 H HB3  B SER A 1 107 ? 5.037   1.852   -10.338 0.500 13.880 0 122  SER A HB3  1 c 
ATOM   1782 H HG   A SER A 1 107 ? 5.606   1.036   -11.115 0.000 6.630  0 122  SER A HG   1 c 
ATOM   1783 H HG   B SER A 1 107 ? 4.448   2.959   -12.131 0.000 16.970 0 122  SER A HG   1 c 
ATOM   1784 N N    . ASP A 1 108 ? 7.299   3.778   -8.280  1.000 10.200 0 123  ASP A N    1 ? 
ATOM   1785 C CA   . ASP A 1 108 ? 8.400   3.540   -7.378  1.000 10.756 0 123  ASP A CA   1 ? 
ATOM   1786 C C    . ASP A 1 108 ? 8.047   3.936   -5.951  1.000 10.953 0 123  ASP A C    1 ? 
ATOM   1787 O O    . ASP A 1 108 ? 8.417   3.201   -5.035  1.000 12.703 0 123  ASP A O    1 ? 
ATOM   1788 C CB   . ASP A 1 108 ? 9.648   4.282   -7.816  1.000 11.414 0 123  ASP A CB   1 ? 
ATOM   1789 C CG   . ASP A 1 108 ? 10.363  3.746   -9.051  1.000 12.703 0 123  ASP A CG   1 ? 
ATOM   1790 O OD1  . ASP A 1 108 ? 10.010  2.653   -9.549  1.000 13.437 0 123  ASP A OD1  1 ? 
ATOM   1791 O OD2  . ASP A 1 108 ? 11.254  4.472   -9.584  1.000 14.971 0 123  ASP A OD2  1 ? 
ATOM   1792 H H    . ASP A 1 108 ? 7.412   4.374   -8.963  1.000 10.335 0 123  ASP A H    1 c 
ATOM   1793 H HA   . ASP A 1 108 ? 8.603   2.578   -7.391  1.000 10.826 0 123  ASP A HA   1 c 
ATOM   1794 H HB2  . ASP A 1 108 ? 9.413   5.216   -7.988  1.000 11.526 0 123  ASP A HB2  1 c 
ATOM   1795 H HB3  . ASP A 1 108 ? 10.291  4.271   -7.076  1.000 11.535 0 123  ASP A HB3  1 c 
ATOM   1796 N N    . VAL A 1 109 ? 7.376   5.064   -5.776  1.000 10.653 0 124  VAL A N    1 ? 
ATOM   1797 C CA   . VAL A 1 109 ? 7.021   5.511   -4.426  1.000 10.694 0 124  VAL A CA   1 ? 
ATOM   1798 C C    . VAL A 1 109 ? 6.111   4.495   -3.763  1.000 10.809 0 124  VAL A C    1 ? 
ATOM   1799 O O    . VAL A 1 109 ? 6.310   4.147   -2.603  1.000 11.897 0 124  VAL A O    1 ? 
ATOM   1800 C CB   . VAL A 1 109 ? 6.398   6.908   -4.493  1.000 11.663 0 124  VAL A CB   1 ? 
ATOM   1801 C CG1  . VAL A 1 109 ? 5.713   7.251   -3.169  1.000 12.820 0 124  VAL A CG1  1 ? 
ATOM   1802 C CG2  . VAL A 1 109 ? 7.465   7.945   -4.848  1.000 13.047 0 124  VAL A CG2  1 ? 
ATOM   1803 H H    . VAL A 1 109 ? 7.135   5.573   -6.496  1.000 10.757 0 124  VAL A H    1 c 
ATOM   1804 H HA   . VAL A 1 109 ? 7.844   5.570   -3.902  1.000 10.904 0 124  VAL A HA   1 c 
ATOM   1805 H HB   . VAL A 1 109 ? 5.718   6.898   -5.207  1.000 11.914 0 124  VAL A HB   1 c 
ATOM   1806 H HG11 . VAL A 1 109 ? 6.295   7.010   -2.429  1.000 12.458 0 124  VAL A HG11 1 c 
ATOM   1807 H HG12 . VAL A 1 109 ? 4.877   6.760   -3.097  1.000 12.457 0 124  VAL A HG12 1 c 
ATOM   1808 H HG13 . VAL A 1 109 ? 5.529   8.205   -3.138  1.000 12.464 0 124  VAL A HG13 1 c 
ATOM   1809 H HG21 . VAL A 1 109 ? 7.041   8.802   -5.019  1.000 12.622 0 124  VAL A HG21 1 c 
ATOM   1810 H HG22 . VAL A 1 109 ? 7.948   7.659   -5.641  1.000 12.571 0 124  VAL A HG22 1 c 
ATOM   1811 H HG23 . VAL A 1 109 ? 8.088   8.035   -4.108  1.000 12.613 0 124  VAL A HG23 1 c 
ATOM   1812 N N    . ILE A 1 110 ? 5.107   3.982   -4.470  1.000 10.452 0 125  ILE A N    1 ? 
ATOM   1813 C CA   . ILE A 1 110 ? 4.221   2.964   -3.906  1.000 10.345 0 125  ILE A CA   1 ? 
ATOM   1814 C C    . ILE A 1 110 ? 5.005   1.695   -3.601  1.000 12.042 0 125  ILE A C    1 ? 
ATOM   1815 O O    . ILE A 1 110 ? 4.950   1.152   -2.480  1.000 12.085 0 125  ILE A O    1 ? 
ATOM   1816 C CB   . ILE A 1 110 ? 3.017   2.699   -4.830  1.000 10.668 0 125  ILE A CB   1 ? 
ATOM   1817 C CG1  . ILE A 1 110 ? 2.149   3.969   -5.065  1.000 11.739 0 125  ILE A CG1  1 ? 
ATOM   1818 C CG2  . ILE A 1 110 ? 2.163   1.545   -4.308  1.000 11.588 0 125  ILE A CG2  1 ? 
ATOM   1819 C CD1  . ILE A 1 110 ? 1.516   4.568   -3.829  1.000 12.316 0 125  ILE A CD1  1 ? 
ATOM   1820 H H    . ILE A 1 110 ? 4.966   4.267   -5.327  1.000 10.530 0 125  ILE A H    1 c 
ATOM   1821 H HA   . ILE A 1 110 ? 3.874   3.309   -3.061  1.000 10.745 0 125  ILE A HA   1 c 
ATOM   1822 H HB   . ILE A 1 110 ? 3.374   2.428   -5.699  1.000 10.965 0 125  ILE A HB   1 c 
ATOM   1823 H HG12 . ILE A 1 110 ? 2.707   4.653   -5.488  1.000 11.597 0 125  ILE A HG12 1 c 
ATOM   1824 H HG13 . ILE A 1 110 ? 1.436   3.742   -5.697  1.000 11.615 0 125  ILE A HG13 1 c 
ATOM   1825 H HG21 . ILE A 1 110 ? 1.311   1.534   -4.775  1.000 11.311 0 125  ILE A HG21 1 c 
ATOM   1826 H HG22 . ILE A 1 110 ? 2.007   1.661   -3.355  1.000 11.311 0 125  ILE A HG22 1 c 
ATOM   1827 H HG23 . ILE A 1 110 ? 2.623   0.702   -4.459  1.000 11.314 0 125  ILE A HG23 1 c 
ATOM   1828 H HD11 . ILE A 1 110 ? 0.970   3.896   -3.379  1.000 12.135 0 125  ILE A HD11 1 c 
ATOM   1829 H HD12 . ILE A 1 110 ? 0.952   5.322   -4.088  1.000 12.137 0 125  ILE A HD12 1 c 
ATOM   1830 H HD13 . ILE A 1 110 ? 2.212   4.880   -3.220  1.000 12.122 0 125  ILE A HD13 1 c 
ATOM   1831 N N    A TRP A 1 111 ? 5.700   1.153   -4.628  0.500 11.678 0 126  TRP A N    1 ? 
ATOM   1832 N N    B TRP A 1 111 ? 5.745   1.241   -4.601  0.500 12.222 0 126  TRP A N    1 ? 
ATOM   1833 C CA   A TRP A 1 111 ? 6.503   -0.061  -4.487  0.500 12.518 0 126  TRP A CA   1 ? 
ATOM   1834 C CA   B TRP A 1 111 ? 6.331   -0.068  -4.512  0.500 13.300 0 126  TRP A CA   1 ? 
ATOM   1835 C C    A TRP A 1 111 ? 7.389   -0.013  -3.259  0.500 13.644 0 126  TRP A C    1 ? 
ATOM   1836 C C    B TRP A 1 111 ? 7.441   -0.088  -3.442  0.500 14.380 0 126  TRP A C    1 ? 
ATOM   1837 O O    A TRP A 1 111 ? 7.474   -0.917  -2.427  0.500 13.305 0 126  TRP A O    1 ? 
ATOM   1838 O O    B TRP A 1 111 ? 7.543   -1.084  -2.708  0.500 14.612 0 126  TRP A O    1 ? 
ATOM   1839 C CB   A TRP A 1 111 ? 7.427   -0.225  -5.704  0.500 12.192 0 126  TRP A CB   1 ? 
ATOM   1840 C CB   B TRP A 1 111 ? 6.691   -0.417  -5.966  0.500 13.090 0 126  TRP A CB   1 ? 
ATOM   1841 C CG   A TRP A 1 111 ? 8.302   -1.448  -5.673  0.500 13.850 0 126  TRP A CG   1 ? 
ATOM   1842 C CG   B TRP A 1 111 ? 7.132   -1.822  -6.200  0.500 14.976 0 126  TRP A CG   1 ? 
ATOM   1843 C CD1  A TRP A 1 111 ? 9.457   -1.674  -4.973  0.500 16.171 0 126  TRP A CD1  1 ? 
ATOM   1844 C CD1  B TRP A 1 111 ? 6.444   -2.923  -6.606  0.500 15.389 0 126  TRP A CD1  1 ? 
ATOM   1845 C CD2  A TRP A 1 111 ? 8.055   -2.635  -6.442  0.500 15.118 0 126  TRP A CD2  1 ? 
ATOM   1846 C CD2  B TRP A 1 111 ? 8.482   -2.237  -5.985  0.500 15.423 0 126  TRP A CD2  1 ? 
ATOM   1847 N NE1  A TRP A 1 111 ? 9.938   -2.920  -5.267  0.500 17.209 0 126  TRP A NE1  1 ? 
ATOM   1848 N NE1  B TRP A 1 111 ? 7.298   -3.994  -6.671  0.500 18.536 0 126  TRP A NE1  1 ? 
ATOM   1849 C CE2  A TRP A 1 111 ? 9.097   -3.537  -6.160  0.500 16.923 0 126  TRP A CE2  1 ? 
ATOM   1850 C CE2  B TRP A 1 111 ? 8.546   -3.608  -6.291  0.500 16.525 0 126  TRP A CE2  1 ? 
ATOM   1851 C CE3  A TRP A 1 111 ? 7.056   -3.001  -7.346  0.500 15.308 0 126  TRP A CE3  1 ? 
ATOM   1852 C CE3  B TRP A 1 111 ? 9.643   -1.565  -5.597  0.500 18.157 0 126  TRP A CE3  1 ? 
ATOM   1853 C CZ2  A TRP A 1 111 ? 9.150   -4.795  -6.755  0.500 17.178 0 126  TRP A CZ2  1 ? 
ATOM   1854 C CZ2  B TRP A 1 111 ? 9.728   -4.335  -6.181  0.500 16.690 0 126  TRP A CZ2  1 ? 
ATOM   1855 C CZ3  A TRP A 1 111 ? 7.116   -4.240  -7.935  0.500 16.467 0 126  TRP A CZ3  1 ? 
ATOM   1856 C CZ3  B TRP A 1 111 ? 10.810  -2.284  -5.507  0.500 19.140 0 126  TRP A CZ3  1 ? 
ATOM   1857 C CH2  A TRP A 1 111 ? 8.167   -5.109  -7.660  0.500 16.504 0 126  TRP A CH2  1 ? 
ATOM   1858 C CH2  B TRP A 1 111 ? 10.849  -3.644  -5.796  0.500 18.817 0 126  TRP A CH2  1 ? 
ATOM   1859 H H    A TRP A 1 111 ? 5.665   1.558   -5.446  0.500 11.928 0 126  TRP A H    1 c 
ATOM   1860 H H    B TRP A 1 111 ? 5.884   1.748   -5.349  0.500 12.385 0 126  TRP A H    1 c 
ATOM   1861 H HA   A TRP A 1 111 ? 5.898   -0.849  -4.428  0.500 12.489 0 126  TRP A HA   1 c 
ATOM   1862 H HA   B TRP A 1 111 ? 5.619   -0.700  -4.222  0.500 13.218 0 126  TRP A HA   1 c 
ATOM   1863 H HB2  A TRP A 1 111 ? 6.871   -0.257  -6.512  0.500 12.636 0 126  TRP A HB2  1 c 
ATOM   1864 H HB2  B TRP A 1 111 ? 5.908   -0.237  -6.529  0.500 13.557 0 126  TRP A HB2  1 c 
ATOM   1865 H HB3  A TRP A 1 111 ? 7.997   0.570   -5.774  0.500 12.653 0 126  TRP A HB3  1 c 
ATOM   1866 H HB3  B TRP A 1 111 ? 7.404   0.188   -6.261  0.500 13.557 0 126  TRP A HB3  1 c 
ATOM   1867 H HD1  A TRP A 1 111 ? 9.870   -1.068  -4.380  0.500 15.873 0 126  TRP A HD1  1 c 
ATOM   1868 H HD1  B TRP A 1 111 ? 5.524   -2.956  -6.817  0.500 15.958 0 126  TRP A HD1  1 c 
ATOM   1869 H HE1  A TRP A 1 111 ? 10.658  -3.275  -4.924  0.500 16.848 0 126  TRP A HE1  1 c 
ATOM   1870 H HE1  B TRP A 1 111 ? 7.067   -4.806  -6.895  0.500 17.230 0 126  TRP A HE1  1 c 
ATOM   1871 H HE3  A TRP A 1 111 ? 6.353   -2.408  -7.545  0.500 15.546 0 126  TRP A HE3  1 c 
ATOM   1872 H HE3  B TRP A 1 111 ? 9.622   -0.646  -5.392  0.500 17.732 0 126  TRP A HE3  1 c 
ATOM   1873 H HZ2  A TRP A 1 111 ? 9.858   -5.390  -6.575  0.500 16.932 0 126  TRP A HZ2  1 c 
ATOM   1874 H HZ2  B TRP A 1 111 ? 9.762   -5.252  -6.395  0.500 17.144 0 126  TRP A HZ2  1 c 
ATOM   1875 H HZ3  A TRP A 1 111 ? 6.447   -4.498  -8.548  0.500 16.158 0 126  TRP A HZ3  1 c 
ATOM   1876 H HZ3  B TRP A 1 111 ? 11.599  -1.849  -5.227  0.500 18.773 0 126  TRP A HZ3  1 c 
ATOM   1877 H HH2  A TRP A 1 111 ? 8.175   -5.959  -8.064  0.500 16.704 0 126  TRP A HH2  1 c 
ATOM   1878 H HH2  B TRP A 1 111 ? 11.660  -4.103  -5.722  0.500 18.474 0 126  TRP A HH2  1 c 
ATOM   1879 N N    . ASN A 1 112 ? 8.175   1.026   -3.229  1.000 14.177 0 127  ASN A N    1 ? 
ATOM   1880 C CA   . ASN A 1 112 ? 9.234   1.124   -2.235  1.000 17.602 0 127  ASN A CA   1 ? 
ATOM   1881 C C    . ASN A 1 112 ? 8.658   1.239   -0.820  1.000 17.640 0 127  ASN A C    1 ? 
ATOM   1882 O O    . ASN A 1 112 ? 9.394   1.024   0.146   1.000 21.125 0 127  ASN A O    1 ? 
ATOM   1883 C CB   . ASN A 1 112 ? 10.184  2.288   -2.514  1.000 19.553 0 127  ASN A CB   1 ? 
ATOM   1884 C CG   . ASN A 1 112 ? 11.103  2.070   -3.693  1.000 22.005 0 127  ASN A CG   1 ? 
ATOM   1885 O OD1  . ASN A 1 112 ? 11.374  0.934   -4.076  1.000 24.338 0 127  ASN A OD1  1 ? 
ATOM   1886 N ND2  . ASN A 1 112 ? 11.623  3.164   -4.243  1.000 23.493 0 127  ASN A ND2  1 ? 
ATOM   1887 H H    . ASN A 1 112 ? 8.032   1.740   -3.782  1.000 14.651 0 127  ASN A H    1 c 
ATOM   1888 H HA   . ASN A 1 112 ? 9.767   0.297   -2.277  1.000 17.195 0 127  ASN A HA   1 c 
ATOM   1889 H HB2  . ASN A 1 112 ? 9.654   3.094   -2.674  1.000 19.557 0 127  ASN A HB2  1 c 
ATOM   1890 H HB3  . ASN A 1 112 ? 10.730  2.447   -1.718  1.000 19.603 0 127  ASN A HB3  1 c 
ATOM   1891 H HD21 . ASN A 1 112 ? 11.489  3.958   -3.870  1.000 22.969 0 127  ASN A HD21 1 c 
ATOM   1892 H HD22 . ASN A 1 112 ? 12.107  3.098   -4.984  1.000 23.021 0 127  ASN A HD22 1 c 
ATOM   1893 N N    . SER A 1 113 ? 7.382   1.613   -0.664  1.000 15.189 0 128  SER A N    1 ? 
ATOM   1894 C CA   . SER A 1 113 ? 6.710   1.745   0.643   1.000 13.955 0 128  SER A CA   1 ? 
ATOM   1895 C C    . SER A 1 113 ? 6.336   0.394   1.234   1.000 15.229 0 128  SER A C    1 ? 
ATOM   1896 O O    . SER A 1 113 ? 5.952   0.328   2.410   1.000 15.666 0 128  SER A O    1 ? 
ATOM   1897 C CB   . SER A 1 113 ? 5.462   2.522   0.447   1.000 14.340 0 128  SER A CB   1 ? 
ATOM   1898 O OG   . SER A 1 113 ? 5.738   3.855   0.044   1.000 18.684 0 128  SER A OG   1 ? 
ATOM   1899 H H    . SER A 1 113 ? 6.900   1.823   -1.411  1.000 15.402 0 128  SER A H    1 c 
ATOM   1900 H HA   . SER A 1 113 ? 7.306   2.226   1.272   1.000 14.510 0 128  SER A HA   1 c 
ATOM   1901 H HB2  . SER A 1 113 ? 4.912   2.086   -0.228  1.000 15.131 0 128  SER A HB2  1 c 
ATOM   1902 H HB3  . SER A 1 113 ? 4.957   2.537   1.283   1.000 15.170 0 128  SER A HB3  1 c 
ATOM   1903 H HG   . SER A 1 113 ? 5.005   4.264   -0.058  0.000 18.680 0 128  SER A HG   1 c 
ATOM   1904 N N    . LEU A 1 114 ? 6.301   -0.642  0.433   1.000 13.187 0 129  LEU A N    1 ? 
ATOM   1905 C CA   . LEU A 1 114 ? 5.733   -1.904  0.841   1.000 13.388 0 129  LEU A CA   1 ? 
ATOM   1906 C C    . LEU A 1 114 ? 6.694   -2.666  1.749   1.000 16.499 0 129  LEU A C    1 ? 
ATOM   1907 O O    . LEU A 1 114 ? 7.906   -2.611  1.557   1.000 17.295 0 129  LEU A O    1 ? 
ATOM   1908 C CB   . LEU A 1 114 ? 5.341   -2.730  -0.363  1.000 13.432 0 129  LEU A CB   1 ? 
ATOM   1909 C CG   . LEU A 1 114 ? 4.325   -2.096  -1.327  1.000 13.598 0 129  LEU A CG   1 ? 
ATOM   1910 C CD1  . LEU A 1 114 ? 4.107   -3.003  -2.506  1.000 15.254 0 129  LEU A CD1  1 ? 
ATOM   1911 C CD2  . LEU A 1 114 ? 2.994   -1.782  -0.660  1.000 14.090 0 129  LEU A CD2  1 ? 
ATOM   1912 H H    . LEU A 1 114 ? 6.641   -0.570  -0.412  1.000 13.726 0 129  LEU A H    1 c 
ATOM   1913 H HA   . LEU A 1 114 ? 4.915   -1.708  1.364   1.000 13.913 0 129  LEU A HA   1 c 
ATOM   1914 H HB2  . LEU A 1 114 ? 6.160   -2.938  -0.870  1.000 13.462 0 129  LEU A HB2  1 c 
ATOM   1915 H HB3  . LEU A 1 114 ? 4.971   -3.584  -0.041  1.000 13.474 0 129  LEU A HB3  1 c 
ATOM   1916 H HG   . LEU A 1 114 ? 4.708   -1.245  -1.662  1.000 13.941 0 129  LEU A HG   1 c 
ATOM   1917 H HD11 . LEU A 1 114 ? 4.950   -3.140  -2.971  1.000 14.741 0 129  LEU A HD11 1 c 
ATOM   1918 H HD12 . LEU A 1 114 ? 3.466   -2.598  -3.114  1.000 14.737 0 129  LEU A HD12 1 c 
ATOM   1919 H HD13 . LEU A 1 114 ? 3.766   -3.858  -2.199  1.000 14.750 0 129  LEU A HD13 1 c 
ATOM   1920 H HD21 . LEU A 1 114 ? 3.119   -1.089  0.010   1.000 13.941 0 129  LEU A HD21 1 c 
ATOM   1921 H HD22 . LEU A 1 114 ? 2.647   -2.584  -0.233  1.000 13.944 0 129  LEU A HD22 1 c 
ATOM   1922 H HD23 . LEU A 1 114 ? 2.360   -1.473  -1.329  1.000 13.948 0 129  LEU A HD23 1 c 
ATOM   1923 N N    . SER A 1 115 ? 6.093   -3.414  2.681   1.000 15.643 0 130  SER A N    1 ? 
ATOM   1924 C CA   . SER A 1 115 ? 6.831   -4.324  3.550   1.000 20.204 0 130  SER A CA   1 ? 
ATOM   1925 C C    . SER A 1 115 ? 7.685   -5.254  2.716   1.000 25.973 0 130  SER A C    1 ? 
ATOM   1926 O O    . SER A 1 115 ? 7.241   -5.739  1.677   1.000 23.797 0 130  SER A O    1 ? 
ATOM   1927 C CB   . SER A 1 115 ? 5.905   -5.169  4.372   1.000 18.972 0 130  SER A CB   1 ? 
ATOM   1928 O OG   . SER A 1 115 ? 5.182   -4.407  5.320   1.000 21.149 0 130  SER A OG   1 ? 
ATOM   1929 H H    . SER A 1 115 ? 5.186   -3.357  2.780   1.000 16.745 0 130  SER A H    1 c 
ATOM   1930 H HA   . SER A 1 115 ? 7.414   -3.794  4.152   1.000 19.992 0 130  SER A HA   1 c 
ATOM   1931 H HB2  . SER A 1 115 ? 5.277   -5.624  3.778   1.000 19.767 0 130  SER A HB2  1 c 
ATOM   1932 H HB3  . SER A 1 115 ? 6.424   -5.852  4.838   1.000 19.783 0 130  SER A HB3  1 c 
ATOM   1933 H HG   . SER A 1 115 ? 4.678   -4.928  5.755   0.000 21.150 0 130  SER A HG   1 c 
ATOM   1934 N N    . ARG A 1 116 ? 8.873   -5.541  3.268   1.000 27.155 0 131  ARG A N    1 ? 
ATOM   1935 C CA   . ARG A 1 116 ? 9.941   -6.246  2.577   1.000 32.070 0 131  ARG A CA   1 ? 
ATOM   1936 C C    . ARG A 1 116 ? 9.529   -7.675  2.247   1.000 34.825 0 131  ARG A C    1 ? 
ATOM   1937 O O    . ARG A 1 116 ? 9.877   -8.172  1.179   1.000 39.535 0 131  ARG A O    1 ? 
ATOM   1938 C CB   . ARG A 1 116 ? 11.174  -6.298  3.487   1.000 30.738 0 131  ARG A CB   1 ? 
ATOM   1939 H H    . ARG A 1 116 ? 9.020   -5.284  4.133   1.000 27.776 0 131  ARG A H    1 c 
ATOM   1940 H HA   . ARG A 1 116 ? 10.155  -5.763  1.739   1.000 31.276 0 131  ARG A HA   1 c 
ATOM   1941 H HB2  . ARG A 1 116 ? 10.941  -6.787  4.305   1.000 31.152 0 131  ARG A HB2  1 c 
ATOM   1942 H HB3  . ARG A 1 116 ? 11.884  -6.793  3.029   0.000 30.680 0 131  ARG A HB3  1 c 
ATOM   1943 N N    . SER A 1 117 ? 8.814   -8.318  3.178   1.000 35.051 0 132  SER A N    1 ? 
ATOM   1944 C CA   . SER A 1 117 ? 8.392   -9.702  3.031   1.000 39.997 0 132  SER A CA   1 ? 
ATOM   1945 C C    . SER A 1 117 ? 6.960   -9.811  3.508   1.000 35.568 0 132  SER A C    1 ? 
ATOM   1946 O O    . SER A 1 117 ? 6.647   -9.406  4.623   1.000 36.365 0 132  SER A O    1 ? 
ATOM   1947 C CB   . SER A 1 117 ? 9.245   -10.688 3.814   1.000 41.967 0 132  SER A CB   1 ? 
ATOM   1948 O OG   . SER A 1 117 ? 10.610  -10.301 3.822   1.000 49.897 0 132  SER A OG   1 ? 
ATOM   1949 H H    . SER A 1 117 ? 8.586   -7.875  3.945   1.000 35.954 0 132  SER A H    1 c 
ATOM   1950 H HA   . SER A 1 117 ? 8.427   -9.943  2.072   1.000 38.421 0 132  SER A HA   1 c 
ATOM   1951 H HB2  . SER A 1 117 ? 8.920   -10.740 4.733   1.000 43.183 0 132  SER A HB2  1 c 
ATOM   1952 H HB3  . SER A 1 117 ? 9.163   -11.574 3.413   1.000 43.253 0 132  SER A HB3  1 c 
ATOM   1953 H HG   . SER A 1 117 ? 11.055  -10.882 4.237   0.000 50.220 0 132  SER A HG   1 c 
ATOM   1954 N N    . TYR A 1 118 ? 6.106   -10.323 2.630   1.000 32.878 0 133  TYR A N    1 ? 
ATOM   1955 C CA   . TYR A 1 118 ? 4.776   -10.729 3.039   1.000 29.550 0 133  TYR A CA   1 ? 
ATOM   1956 C C    . TYR A 1 118 ? 4.216   -11.660 1.978   1.000 29.125 0 133  TYR A C    1 ? 
ATOM   1957 O O    . TYR A 1 118 ? 4.744   -11.712 0.866   1.000 28.927 0 133  TYR A O    1 ? 
ATOM   1958 C CB   . TYR A 1 118 ? 3.786   -9.585  3.262   1.000 26.400 0 133  TYR A CB   1 ? 
ATOM   1959 C CG   . TYR A 1 118 ? 3.532   -8.637  2.094   1.000 22.983 0 133  TYR A CG   1 ? 
ATOM   1960 C CD1  . TYR A 1 118 ? 4.455   -7.637  1.814   1.000 21.909 0 133  TYR A CD1  1 ? 
ATOM   1961 C CD2  . TYR A 1 118 ? 2.391   -8.722  1.294   1.000 21.697 0 133  TYR A CD2  1 ? 
ATOM   1962 C CE1  . TYR A 1 118 ? 4.238   -6.724  0.791   1.000 19.897 0 133  TYR A CE1  1 ? 
ATOM   1963 C CE2  . TYR A 1 118 ? 2.164   -7.820  0.257   1.000 19.863 0 133  TYR A CE2  1 ? 
ATOM   1964 C CZ   . TYR A 1 118 ? 3.070   -6.785  0.035   1.000 18.431 0 133  TYR A CZ   1 ? 
ATOM   1965 O OH   . TYR A 1 118 ? 2.911   -5.856  -0.962  1.000 16.676 0 133  TYR A OH   1 ? 
ATOM   1966 H H    . TYR A 1 118 ? 6.352   -10.420 1.755   1.000 32.866 0 133  TYR A H    1 c 
ATOM   1967 H HA   . TYR A 1 118 ? 4.856   -11.240 3.888   1.000 29.540 0 133  TYR A HA   1 c 
ATOM   1968 H HB2  . TYR A 1 118 ? 2.926   -9.975  3.535   1.000 26.299 0 133  TYR A HB2  1 c 
ATOM   1969 H HB3  . TYR A 1 118 ? 4.107   -9.053  4.024   1.000 26.299 0 133  TYR A HB3  1 c 
ATOM   1970 H HD1  . TYR A 1 118 ? 5.225   -7.551  2.354   1.000 21.625 0 133  TYR A HD1  1 c 
ATOM   1971 H HD2  . TYR A 1 118 ? 1.749   -9.390  1.473   1.000 21.560 0 133  TYR A HD2  1 c 
ATOM   1972 H HE1  . TYR A 1 118 ? 4.859   -6.034  0.636   1.000 20.028 0 133  TYR A HE1  1 c 
ATOM   1973 H HE2  . TYR A 1 118 ? 1.375   -7.873  -0.253  1.000 19.876 0 133  TYR A HE2  1 c 
ATOM   1974 H HH   . TYR A 1 118 ? 3.240   -6.153  -1.696  0.000 16.680 0 133  TYR A HH   1 c 
ATOM   1975 N N    . PHE A 1 119 ? 3.112   -12.329 2.335   1.000 28.390 0 134  PHE A N    1 ? 
ATOM   1976 C CA   . PHE A 1 119 ? 2.384   -13.193 1.415   1.000 31.706 0 134  PHE A CA   1 ? 
ATOM   1977 C C    . PHE A 1 119 ? 1.499   -12.312 0.531   1.000 30.247 0 134  PHE A C    1 ? 
ATOM   1978 O O    . PHE A 1 119 ? 0.592   -11.634 1.019   1.000 28.477 0 134  PHE A O    1 ? 
ATOM   1979 C CB   . PHE A 1 119 ? 1.585   -14.238 2.210   1.000 37.413 0 134  PHE A CB   1 ? 
ATOM   1980 C CG   . PHE A 1 119 ? 2.415   -15.036 3.210   1.000 43.566 0 134  PHE A CG   1 ? 
ATOM   1981 C CD1  . PHE A 1 119 ? 2.932   -16.285 2.867   1.000 48.577 0 134  PHE A CD1  1 ? 
ATOM   1982 C CD2  . PHE A 1 119 ? 2.700   -14.525 4.477   1.000 46.345 0 134  PHE A CD2  1 ? 
ATOM   1983 C CE1  . PHE A 1 119 ? 3.701   -17.011 3.770   1.000 47.957 0 134  PHE A CE1  1 ? 
ATOM   1984 C CE2  . PHE A 1 119 ? 3.478   -15.252 5.369   1.000 51.971 0 134  PHE A CE2  1 ? 
ATOM   1985 C CZ   . PHE A 1 119 ? 3.973   -16.493 5.016   1.000 48.189 0 134  PHE A CZ   1 ? 
ATOM   1986 H H    . PHE A 1 119 ? 2.788   -12.223 3.182   1.000 29.563 0 134  PHE A H    1 c 
ATOM   1987 H HA   . PHE A 1 119 ? 3.041   -13.669 0.840   1.000 31.661 0 134  PHE A HA   1 c 
ATOM   1988 H HB2  . PHE A 1 119 ? 0.868   -13.778 2.693   1.000 37.402 0 134  PHE A HB2  1 c 
ATOM   1989 H HB3  . PHE A 1 119 ? 1.168   -14.861 1.575   1.000 37.326 0 134  PHE A HB3  1 c 
ATOM   1990 H HD1  . PHE A 1 119 ? 2.751   -16.644 2.013   1.000 47.191 0 134  PHE A HD1  1 c 
ATOM   1991 H HD2  . PHE A 1 119 ? 2.367   -13.678 4.727   1.000 46.700 0 134  PHE A HD2  1 c 
ATOM   1992 H HE1  . PHE A 1 119 ? 4.040   -17.857 3.525   1.000 48.118 0 134  PHE A HE1  1 c 
ATOM   1993 H HE2  . PHE A 1 119 ? 3.658   -14.902 6.226   1.000 49.623 0 134  PHE A HE2  1 c 
ATOM   1994 H HZ   . PHE A 1 119 ? 4.492   -16.986 5.629   1.000 48.923 0 134  PHE A HZ   1 c 
ATOM   1995 N N    . LYS A 1 120 ? 1.789   -12.307 -0.775  1.000 29.469 0 135  LYS A N    1 ? 
ATOM   1996 C CA   . LYS A 1 120 ? 1.135   -11.415 -1.730  1.000 35.229 0 135  LYS A CA   1 ? 
ATOM   1997 C C    . LYS A 1 120 ? -0.248  -11.909 -2.161  1.000 31.656 0 135  LYS A C    1 ? 
ATOM   1998 O O    . LYS A 1 120 ? -0.945  -11.175 -2.861  1.000 34.081 0 135  LYS A O    1 ? 
ATOM   1999 C CB   . LYS A 1 120 ? 1.971   -11.318 -3.015  1.000 38.908 0 135  LYS A CB   1 ? 
ATOM   2000 C CG   . LYS A 1 120 ? 3.029   -10.242 -3.001  1.000 41.356 0 135  LYS A CG   1 ? 
ATOM   2001 C CD   . LYS A 1 120 ? 4.103   -10.336 -1.933  1.000 46.398 0 135  LYS A CD   1 ? 
ATOM   2002 C CE   . LYS A 1 120 ? 5.040   -9.191  -2.065  1.000 43.968 0 135  LYS A CE   1 ? 
ATOM   2003 N NZ   . LYS A 1 120 ? 6.170   -9.330  -1.144  1.000 49.562 0 135  LYS A NZ   1 ? 
ATOM   2004 H H    . LYS A 1 120 ? 2.421   -12.889 -1.087  1.000 30.990 0 135  LYS A H    1 c 
ATOM   2005 H HA   . LYS A 1 120 ? 1.047   -10.517 -1.321  1.000 33.922 0 135  LYS A HA   1 c 
ATOM   2006 H HB2  . LYS A 1 120 ? 2.409   -12.180 -3.173  1.000 38.470 0 135  LYS A HB2  1 c 
ATOM   2007 H HB3  . LYS A 1 120 ? 1.372   -11.147 -3.772  1.000 38.494 0 135  LYS A HB3  1 c 
ATOM   2008 H HG2  . LYS A 1 120 ? 3.467   -10.240 -3.880  1.000 41.813 0 135  LYS A HG2  1 c 
ATOM   2009 H HG3  . LYS A 1 120 ? 2.576   -9.376  -2.906  1.000 41.487 0 135  LYS A HG3  1 c 
ATOM   2010 H HD2  . LYS A 1 120 ? 3.687   -10.315 -1.044  1.000 44.494 0 135  LYS A HD2  1 c 
ATOM   2011 H HD3  . LYS A 1 120 ? 4.599   -11.178 -2.033  1.000 44.637 0 135  LYS A HD3  1 c 
ATOM   2012 H HE2  . LYS A 1 120 ? 5.378   -9.150  -2.975  1.000 45.679 0 135  LYS A HE2  1 c 
ATOM   2013 H HE3  . LYS A 1 120 ? 4.572   -8.358  -1.874  1.000 45.570 0 135  LYS A HE3  1 c 
ATOM   2014 H HZ1  . LYS A 1 120 ? 6.608   -10.106 -1.310  1.000 47.710 0 135  LYS A HZ1  1 c 
ATOM   2015 H HZ2  . LYS A 1 120 ? 5.869   -9.335  -0.290  1.000 47.637 0 135  LYS A HZ2  1 c 
ATOM   2016 H HZ3  . LYS A 1 120 ? 6.742   -8.636  -1.254  1.000 47.732 0 135  LYS A HZ3  1 c 
ATOM   2017 N N    A ASP A 1 121 ? -0.584  -13.133 -1.722  0.500 32.720 0 136  ASP A N    1 ? 
ATOM   2018 N N    B ASP A 1 121 ? -0.612  -13.155 -1.818  0.500 34.124 0 136  ASP A N    1 ? 
ATOM   2019 C CA   A ASP A 1 121 ? -1.773  -13.888 -2.094  0.500 32.054 0 136  ASP A CA   1 ? 
ATOM   2020 C CA   B ASP A 1 121 ? -1.893  -13.741 -2.204  0.500 34.154 0 136  ASP A CA   1 ? 
ATOM   2021 C C    A ASP A 1 121 ? -2.889  -13.668 -1.071  0.500 30.579 0 136  ASP A C    1 ? 
ATOM   2022 C C    B ASP A 1 121 ? -2.812  -13.833 -0.980  0.500 32.275 0 136  ASP A C    1 ? 
ATOM   2023 O O    A ASP A 1 121 ? -4.027  -14.094 -1.273  0.500 31.882 0 136  ASP A O    1 ? 
ATOM   2024 O O    B ASP A 1 121 ? -3.728  -14.656 -0.939  0.500 34.003 0 136  ASP A O    1 ? 
ATOM   2025 C CB   A ASP A 1 121 ? -1.454  -15.376 -2.109  0.500 29.787 0 136  ASP A CB   1 ? 
ATOM   2026 C CB   B ASP A 1 121 ? -1.711  -15.077 -2.913  0.500 34.621 0 136  ASP A CB   1 ? 
ATOM   2027 C CG   A ASP A 1 121 ? -0.861  -15.922 -0.818  0.500 29.847 0 136  ASP A CG   1 ? 
ATOM   2028 C CG   B ASP A 1 121 ? -1.009  -15.011 -4.263  0.500 32.798 0 136  ASP A CG   1 ? 
ATOM   2029 H H    A ASP A 1 121 ? -0.008  -13.540 -1.142  0.500 32.255 0 136  ASP A H    1 c 
ATOM   2030 H H    B ASP A 1 121 ? -0.034  -13.666 -1.329  0.500 33.483 0 136  ASP A H    1 c 
ATOM   2031 H HA   A ASP A 1 121 ? -2.077  -13.595 -2.982  0.500 31.534 0 136  ASP A HA   1 c 
ATOM   2032 H HA   B ASP A 1 121 ? -2.316  -13.148 -2.860  0.500 33.910 0 136  ASP A HA   1 c 
ATOM   2033 H HB2  A ASP A 1 121 ? -2.277  -15.872 -2.301  0.500 30.303 0 136  ASP A HB2  1 c 
ATOM   2034 H HB2  B ASP A 1 121 ? -1.195  -15.673 -2.331  0.500 34.088 0 136  ASP A HB2  1 c 
ATOM   2035 H HB3  A ASP A 1 121 ? -0.820  -15.553 -2.834  0.500 30.304 0 136  ASP A HB3  1 c 
ATOM   2036 H HB3  B ASP A 1 121 ? -2.594  -15.481 -3.050  0.500 34.088 0 136  ASP A HB3  1 c 
ATOM   2037 N N    . ARG A 1 122 ? -2.545  -12.995 0.028   1.000 26.951 0 137  ARG A N    1 ? 
ATOM   2038 C CA   . ARG A 1 122 ? -3.439  -12.842 1.162   1.000 23.260 0 137  ARG A CA   1 ? 
ATOM   2039 C C    . ARG A 1 122 ? -4.687  -12.034 0.779   1.000 17.622 0 137  ARG A C    1 ? 
ATOM   2040 O O    . ARG A 1 122 ? -4.685  -11.228 -0.130  1.000 16.151 0 137  ARG A O    1 ? 
ATOM   2041 C CB   . ARG A 1 122 ? -2.696  -12.154 2.306   1.000 25.893 0 137  ARG A CB   1 ? 
ATOM   2042 C CG   . ARG A 1 122 ? -1.852  -13.028 3.220   1.000 38.051 0 137  ARG A CG   1 ? 
ATOM   2043 C CD   . ARG A 1 122 ? -0.902  -12.177 4.054   1.000 47.188 0 137  ARG A CD   1 ? 
ATOM   2044 N NE   . ARG A 1 122 ? -1.551  -10.941 4.510   1.000 49.341 0 137  ARG A NE   1 ? 
ATOM   2045 C CZ   . ARG A 1 122 ? -1.891  -10.663 5.758   1.000 56.662 0 137  ARG A CZ   1 ? 
ATOM   2046 N NH1  . ARG A 1 122 ? -1.601  -11.520 6.723   1.000 61.620 0 137  ARG A NH1  1 ? 
ATOM   2047 N NH2  . ARG A 1 122 ? -2.508  -9.529  6.038   1.000 56.719 0 137  ARG A NH2  1 ? 
ATOM   2048 H H    . ARG A 1 122 ? -1.747  -12.553 0.047   1.000 27.974 0 137  ARG A H    1 c 
ATOM   2049 H HA   . ARG A 1 122 ? -3.721  -13.743 1.462   1.000 23.230 0 137  ARG A HA   1 c 
ATOM   2050 H HB2  . ARG A 1 122 ? -2.115  -11.465 1.919   1.000 27.929 0 137  ARG A HB2  1 c 
ATOM   2051 H HB3  . ARG A 1 122 ? -3.362  -11.692 2.859   1.000 27.807 0 137  ARG A HB3  1 c 
ATOM   2052 H HG2  . ARG A 1 122 ? -2.439  -13.538 3.819   1.000 36.578 0 137  ARG A HG2  1 c 
ATOM   2053 H HG3  . ARG A 1 122 ? -1.333  -13.661 2.679   1.000 36.580 0 137  ARG A HG3  1 c 
ATOM   2054 H HD2  . ARG A 1 122 ? -0.597  -12.693 4.827   1.000 45.620 0 137  ARG A HD2  1 c 
ATOM   2055 H HD3  . ARG A 1 122 ? -0.118  -11.947 3.517   1.000 45.291 0 137  ARG A HD3  1 c 
ATOM   2056 H HE   . ARG A 1 122 ? -1.712  -10.328 3.913   1.000 49.862 0 137  ARG A HE   1 c 
ATOM   2057 H HH11 . ARG A 1 122 ? -1.086  -11.262 7.400   1.000 59.995 0 137  ARG A HH11 1 c 
ATOM   2058 H HH12 . ARG A 1 122 ? -1.928  -12.345 6.694   1.000 59.819 0 137  ARG A HH12 1 c 
ATOM   2059 H HH21 . ARG A 1 122 ? -2.733  -9.348  6.874   1.000 56.708 0 137  ARG A HH21 1 c 
ATOM   2060 H HH22 . ARG A 1 122 ? -2.694  -8.953  5.393   1.000 56.585 0 137  ARG A HH22 1 c 
ATOM   2061 N N    . ALA A 1 123 ? -5.760  -12.288 1.510   1.000 15.749 0 138  ALA A N    1 ? 
ATOM   2062 C CA   . ALA A 1 123 ? -6.986  -11.530 1.426   1.000 14.373 0 138  ALA A CA   1 ? 
ATOM   2063 C C    . ALA A 1 123 ? -6.805  -10.212 2.157   1.000 11.886 0 138  ALA A C    1 ? 
ATOM   2064 O O    . ALA A 1 123 ? -6.000  -10.069 3.071   1.000 12.911 0 138  ALA A O    1 ? 
ATOM   2065 C CB   . ALA A 1 123 ? -8.141  -12.301 2.067   1.000 14.881 0 138  ALA A CB   1 ? 
ATOM   2066 H H    . ALA A 1 123 ? -5.725  -12.982 2.103   1.000 15.930 0 138  ALA A H    1 c 
ATOM   2067 H HA   . ALA A 1 123 ? -7.190  -11.347 0.467   1.000 14.202 0 138  ALA A HA   1 c 
ATOM   2068 H HB1  . ALA A 1 123 ? -8.264  -13.148 1.606   1.000 14.730 0 138  ALA A HB1  1 c 
ATOM   2069 H HB2  . ALA A 1 123 ? -7.942  -12.470 3.003   1.000 14.730 0 138  ALA A HB2  1 c 
ATOM   2070 H HB3  . ALA A 1 123 ? -8.958  -11.778 2.002   1.000 14.730 0 138  ALA A HB3  1 c 
ATOM   2071 N N    . HIS A 1 124 ? -7.567  -9.231  1.718   1.000 11.451 0 139  HIS A N    1 ? 
ATOM   2072 C CA   . HIS A 1 124 ? -7.728  -7.974  2.412   1.000 9.892  0 139  HIS A CA   1 ? 
ATOM   2073 C C    . HIS A 1 124 ? -6.492  -7.092  2.358   1.000 10.264 0 139  HIS A C    1 ? 
ATOM   2074 O O    . HIS A 1 124 ? -6.307  -6.226  3.192   1.000 12.225 0 139  HIS A O    1 ? 
ATOM   2075 C CB   . HIS A 1 124 ? -8.194  -8.166  3.869   1.000 10.825 0 139  HIS A CB   1 ? 
ATOM   2076 C CG   . HIS A 1 124 ? -9.258  -9.155  4.022   1.000 11.548 0 139  HIS A CG   1 ? 
ATOM   2077 N ND1  . HIS A 1 124 ? -10.509 -9.048  3.486   1.000 10.488 0 139  HIS A ND1  1 ? 
ATOM   2078 C CD2  . HIS A 1 124 ? -9.236  -10.315 4.708   1.000 11.821 0 139  HIS A CD2  1 ? 
ATOM   2079 C CE1  . HIS A 1 124 ? -11.206 -10.145 3.778   1.000 11.861 0 139  HIS A CE1  1 ? 
ATOM   2080 N NE2  . HIS A 1 124 ? -10.442 -10.916 4.534   1.000 12.517 0 139  HIS A NE2  1 ? 
ATOM   2081 H H    . HIS A 1 124 ? -8.020  -9.348  0.933   1.000 11.216 0 139  HIS A H    1 c 
ATOM   2082 H HA   . HIS A 1 124 ? -8.454  -7.495  1.942   1.000 10.414 0 139  HIS A HA   1 c 
ATOM   2083 H HB2  . HIS A 1 124 ? -7.425  -8.437  4.415   1.000 10.789 0 139  HIS A HB2  1 c 
ATOM   2084 H HB3  . HIS A 1 124 ? -8.513  -7.303  4.213   1.000 10.784 0 139  HIS A HB3  1 c 
ATOM   2085 H HD1  . HIS A 1 124 ? -10.798 -8.375  2.997   0.000 10.490 0 139  HIS A HD1  1 c 
ATOM   2086 H HD2  . HIS A 1 124 ? -8.511  -10.672 5.182   1.000 11.899 0 139  HIS A HD2  1 c 
ATOM   2087 H HE1  . HIS A 1 124 ? -12.098 -10.315 3.538   1.000 11.692 0 139  HIS A HE1  1 c 
ATOM   2088 H HE2  . HIS A 1 124 ? -10.670 -11.698 4.859   0.000 12.520 0 139  HIS A HE2  1 c 
ATOM   2089 N N    . ILE A 1 125 ? -5.691  -7.229  1.296   1.000 9.192  0 140  ILE A N    1 ? 
ATOM   2090 C CA   . ILE A 1 125 ? -4.537  -6.346  1.093   1.000 9.543  0 140  ILE A CA   1 ? 
ATOM   2091 C C    . ILE A 1 125 ? -4.666  -5.593  -0.235  1.000 8.838  0 140  ILE A C    1 ? 
ATOM   2092 O O    . ILE A 1 125 ? -3.675  -5.317  -0.941  1.000 9.449  0 140  ILE A O    1 ? 
ATOM   2093 C CB   . ILE A 1 125 ? -3.184  -7.070  1.253   1.000 10.184 0 140  ILE A CB   1 ? 
ATOM   2094 C CG1  . ILE A 1 125 ? -2.979  -8.200  0.227   1.000 11.639 0 140  ILE A CG1  1 ? 
ATOM   2095 C CG2  . ILE A 1 125 ? -3.025  -7.571  2.705   1.000 10.734 0 140  ILE A CG2  1 ? 
ATOM   2096 C CD1  . ILE A 1 125 ? -1.525  -8.685  0.110   1.000 13.217 0 140  ILE A CD1  1 ? 
ATOM   2097 H H    . ILE A 1 125 ? -5.863  -7.879  0.677   1.000 9.543  0 140  ILE A H    1 c 
ATOM   2098 H HA   . ILE A 1 125 ? -4.572  -5.674  1.796   1.000 9.477  0 140  ILE A HA   1 c 
ATOM   2099 H HB   . ILE A 1 125 ? -2.481  -6.408  1.096   1.000 10.412 0 140  ILE A HB   1 c 
ATOM   2100 H HG12 . ILE A 1 125 ? -3.542  -8.958  0.481   1.000 11.634 0 140  ILE A HG12 1 c 
ATOM   2101 H HG13 . ILE A 1 125 ? -3.277  -7.888  -0.651  1.000 11.579 0 140  ILE A HG13 1 c 
ATOM   2102 H HG21 . ILE A 1 125 ? -2.146  -7.970  2.819   1.000 10.595 0 140  ILE A HG21 1 c 
ATOM   2103 H HG22 . ILE A 1 125 ? -3.708  -8.235  2.898   1.000 10.570 0 140  ILE A HG22 1 c 
ATOM   2104 H HG23 . ILE A 1 125 ? -3.121  -6.823  3.319   1.000 10.575 0 140  ILE A HG23 1 c 
ATOM   2105 H HD11 . ILE A 1 125 ? -0.951  -7.934  -0.135  1.000 12.773 0 140  ILE A HD11 1 c 
ATOM   2106 H HD12 . ILE A 1 125 ? -1.465  -9.375  -0.577  1.000 12.741 0 140  ILE A HD12 1 c 
ATOM   2107 H HD13 . ILE A 1 125 ? -1.230  -9.052  0.964   1.000 12.729 0 140  ILE A HD13 1 c 
ATOM   2108 N N    . GLN A 1 126 ? -5.908  -5.288  -0.620  1.000 8.381  0 141  GLN A N    1 ? 
ATOM   2109 C CA   . GLN A 1 126 ? -6.207  -4.673  -1.924  1.000 8.210  0 141  GLN A CA   1 ? 
ATOM   2110 C C    . GLN A 1 126 ? -6.351  -3.152  -1.848  1.000 8.284  0 141  GLN A C    1 ? 
ATOM   2111 O O    . GLN A 1 126 ? -6.221  -2.463  -2.888  1.000 9.564  0 141  GLN A O    1 ? 
ATOM   2112 C CB   . GLN A 1 126 ? -7.442  -5.277  -2.563  1.000 8.697  0 141  GLN A CB   1 ? 
ATOM   2113 C CG   . GLN A 1 126 ? -8.798  -4.908  -1.966  1.000 8.563  0 141  GLN A CG   1 ? 
ATOM   2114 C CD   . GLN A 1 126 ? -9.133  -5.543  -0.626  1.000 8.713  0 141  GLN A CD   1 ? 
ATOM   2115 O OE1  . GLN A 1 126 ? -8.402  -5.448  0.363   1.000 9.568  0 141  GLN A OE1  1 ? 
ATOM   2116 N NE2  . GLN A 1 126 ? -10.294 -6.181  -0.557  1.000 9.263  0 141  GLN A NE2  1 ? 
ATOM   2117 H H    . GLN A 1 126 ? -6.600  -5.455  -0.048  1.000 8.465  0 141  GLN A H    1 c 
ATOM   2118 H HA   . GLN A 1 126 ? -5.450  -4.870  -2.531  1.000 8.355  0 141  GLN A HA   1 c 
ATOM   2119 H HB2  . GLN A 1 126 ? -7.445  -5.019  -3.508  1.000 8.560  0 141  GLN A HB2  1 c 
ATOM   2120 H HB3  . GLN A 1 126 ? -7.349  -6.252  -2.532  1.000 8.553  0 141  GLN A HB3  1 c 
ATOM   2121 H HG2  . GLN A 1 126 ? -8.844  -3.935  -1.858  1.000 8.627  0 141  GLN A HG2  1 c 
ATOM   2122 H HG3  . GLN A 1 126 ? -9.498  -5.160  -2.604  1.000 8.633  0 141  GLN A HG3  1 c 
ATOM   2123 H HE21 . GLN A 1 126 ? -10.988 -5.895  -1.030  1.000 9.083  0 141  GLN A HE21 1 c 
ATOM   2124 H HE22 . GLN A 1 126 ? -10.375 -6.892  -0.032  1.000 9.092  0 141  GLN A HE22 1 c 
ATOM   2125 N N    . SER A 1 127 ? -6.678  -2.603  -0.670  1.000 7.428  0 142  SER A N    1 ? 
ATOM   2126 C CA   . SER A 1 127 ? -7.152  -1.239  -0.533  1.000 7.908  0 142  SER A CA   1 ? 
ATOM   2127 C C    . SER A 1 127 ? -6.086  -0.297  -0.008  1.000 8.235  0 142  SER A C    1 ? 
ATOM   2128 O O    . SER A 1 127 ? -5.070  -0.705  0.553   1.000 8.623  0 142  SER A O    1 ? 
ATOM   2129 C CB   . SER A 1 127 ? -8.374  -1.154  0.407   1.000 8.220  0 142  SER A CB   1 ? 
ATOM   2130 O OG   . SER A 1 127 ? -7.898  -1.424  1.742   1.000 9.814  0 142  SER A OG   1 ? 
ATOM   2131 H H    . SER A 1 127 ? -6.598  -3.108  0.087   1.000 7.746  0 142  SER A H    1 c 
ATOM   2132 H HA   . SER A 1 127 ? -7.429  -0.918  -1.427  1.000 7.943  0 142  SER A HA   1 c 
ATOM   2133 H HB2  . SER A 1 127 ? -8.768  -0.261  0.364   1.000 8.505  0 142  SER A HB2  1 c 
ATOM   2134 H HB3  . SER A 1 127 ? -9.043  -1.816  0.148   1.000 8.505  0 142  SER A HB3  1 c 
ATOM   2135 H HG   . SER A 1 127 ? -8.553  -1.381  2.275   0.000 9.820  0 142  SER A HG   1 c 
ATOM   2136 N N    . LEU A 1 128 ? -6.329  0.997   -0.107  1.000 8.420  0 143  LEU A N    1 ? 
ATOM   2137 C CA   . LEU A 1 128 ? -5.421  1.963   0.487   1.000 9.095  0 143  LEU A CA   1 ? 
ATOM   2138 C C    . LEU A 1 128 ? -5.394  1.867   2.008   1.000 8.731  0 143  LEU A C    1 ? 
ATOM   2139 O O    . LEU A 1 128 ? -4.416  2.292   2.607   1.000 8.922  0 143  LEU A O    1 ? 
ATOM   2140 C CB   . LEU A 1 128 ? -5.751  3.366   0.009   1.000 9.880  0 143  LEU A CB   1 ? 
ATOM   2141 C CG   . LEU A 1 128 ? -5.501  3.608   -1.476  1.000 11.163 0 143  LEU A CG   1 ? 
ATOM   2142 C CD1  . LEU A 1 128 ? -5.781  5.054   -1.816  1.000 12.376 0 143  LEU A CD1  1 ? 
ATOM   2143 C CD2  . LEU A 1 128 ? -4.116  3.179   -1.945  1.000 11.855 0 143  LEU A CD2  1 ? 
ATOM   2144 H H    . LEU A 1 128 ? -7.071  1.293   -0.551  1.000 8.526  0 143  LEU A H    1 c 
ATOM   2145 H HA   . LEU A 1 128 ? -4.509  1.738   0.173   1.000 9.051  0 143  LEU A HA   1 c 
ATOM   2146 H HB2  . LEU A 1 128 ? -6.701  3.542   0.199   1.000 9.966  0 143  LEU A HB2  1 c 
ATOM   2147 H HB3  . LEU A 1 128 ? -5.209  4.006   0.526   1.000 9.960  0 143  LEU A HB3  1 c 
ATOM   2148 H HG   . LEU A 1 128 ? -6.157  3.061   -1.979  1.000 11.252 0 143  LEU A HG   1 c 
ATOM   2149 H HD11 . LEU A 1 128 ? -6.680  5.285   -1.529  1.000 11.975 0 143  LEU A HD11 1 c 
ATOM   2150 H HD12 . LEU A 1 128 ? -5.706  5.183   -2.777  1.000 11.994 0 143  LEU A HD12 1 c 
ATOM   2151 H HD13 . LEU A 1 128 ? -5.140  5.626   -1.362  1.000 11.996 0 143  LEU A HD13 1 c 
ATOM   2152 H HD21 . LEU A 1 128 ? -4.081  2.210   -2.016  1.000 11.612 0 143  LEU A HD21 1 c 
ATOM   2153 H HD22 . LEU A 1 128 ? -3.448  3.480   -1.306  1.000 11.640 0 143  LEU A HD22 1 c 
ATOM   2154 H HD23 . LEU A 1 128 ? -3.931  3.572   -2.815  1.000 11.645 0 143  LEU A HD23 1 c 
ATOM   2155 N N    . PHE A 1 129 ? -6.455  1.351   2.643   1.000 8.750  0 144  PHE A N    1 ? 
ATOM   2156 C CA   . PHE A 1 129 ? -6.375  1.090   4.077   1.000 8.680  0 144  PHE A CA   1 ? 
ATOM   2157 C C    . PHE A 1 129 ? -5.262  0.121   4.383   1.000 8.548  0 144  PHE A C    1 ? 
ATOM   2158 O O    . PHE A 1 129 ? -4.492  0.316   5.344   1.000 8.695  0 144  PHE A O    1 ? 
ATOM   2159 C CB   . PHE A 1 129 ? -7.720  0.580   4.593   1.000 9.477  0 144  PHE A CB   1 ? 
ATOM   2160 C CG   . PHE A 1 129 ? -7.761  0.343   6.095   1.000 9.099  0 144  PHE A CG   1 ? 
ATOM   2161 C CD1  . PHE A 1 129 ? -8.136  1.369   6.935   1.000 9.489  0 144  PHE A CD1  1 ? 
ATOM   2162 C CD2  . PHE A 1 129 ? -7.489  -0.882  6.619   1.000 9.740  0 144  PHE A CD2  1 ? 
ATOM   2163 C CE1  . PHE A 1 129 ? -8.178  1.206   8.303   1.000 9.876  0 144  PHE A CE1  1 ? 
ATOM   2164 C CE2  . PHE A 1 129 ? -7.515  -1.048  8.004   1.000 10.197 0 144  PHE A CE2  1 ? 
ATOM   2165 C CZ   . PHE A 1 129 ? -7.869  -0.032  8.806   1.000 10.115 0 144  PHE A CZ   1 ? 
ATOM   2166 H H    . PHE A 1 129 ? -7.230  1.172   2.193   1.000 8.730  0 144  PHE A H    1 c 
ATOM   2167 H HA   . PHE A 1 129 ? -6.174  1.949   4.536   1.000 8.809  0 144  PHE A HA   1 c 
ATOM   2168 H HB2  . PHE A 1 129 ? -8.415  1.232   4.353   1.000 9.205  0 144  PHE A HB2  1 c 
ATOM   2169 H HB3  . PHE A 1 129 ? -7.925  -0.265  4.136   1.000 9.202  0 144  PHE A HB3  1 c 
ATOM   2170 H HD1  . PHE A 1 129 ? -8.333  2.215   6.565   1.000 9.496  0 144  PHE A HD1  1 c 
ATOM   2171 H HD2  . PHE A 1 129 ? -7.226  -1.592  6.056   1.000 9.689  0 144  PHE A HD2  1 c 
ATOM   2172 H HE1  . PHE A 1 129 ? -8.423  1.918   8.872   1.000 9.837  0 144  PHE A HE1  1 c 
ATOM   2173 H HE2  . PHE A 1 129 ? -7.317  -1.893  8.377   1.000 10.058 0 144  PHE A HE2  1 c 
ATOM   2174 H HZ   . PHE A 1 129 ? -7.902  -0.171  9.739   1.000 10.065 0 144  PHE A HZ   1 c 
ATOM   2175 N N    . SER A 1 130 ? -5.128  -0.955  3.606   1.000 9.109  0 145  SER A N    1 ? 
ATOM   2176 C CA   . SER A 1 130 ? -4.062  -1.915  3.805   1.000 9.096  0 145  SER A CA   1 ? 
ATOM   2177 C C    . SER A 1 130 ? -2.710  -1.255  3.557   1.000 9.773  0 145  SER A C    1 ? 
ATOM   2178 O O    . SER A 1 130 ? -1.717  -1.485  4.266   1.000 9.783  0 145  SER A O    1 ? 
ATOM   2179 C CB   . SER A 1 130 ? -4.258  -3.116  2.892   1.000 9.225  0 145  SER A CB   1 ? 
ATOM   2180 O OG   . SER A 1 130 ? -3.212  -4.048  3.020   1.000 10.310 0 145  SER A OG   1 ? 
ATOM   2181 H H    . SER A 1 130 ? -5.727  -1.097  2.931   1.000 8.968  0 145  SER A H    1 c 
ATOM   2182 H HA   . SER A 1 130 ? -4.092  -2.225  4.746   1.000 9.236  0 145  SER A HA   1 c 
ATOM   2183 H HB2  . SER A 1 130 ? -5.105  -3.549  3.108   1.000 9.476  0 145  SER A HB2  1 c 
ATOM   2184 H HB3  . SER A 1 130 ? -4.304  -2.810  1.966   1.000 9.445  0 145  SER A HB3  1 c 
ATOM   2185 H HG   . SER A 1 130 ? -3.361  -4.695  2.496   0.000 10.310 0 145  SER A HG   1 c 
ATOM   2186 N N    . PHE A 1 131 ? -2.591  -0.452  2.497   1.000 8.668  0 146  PHE A N    1 ? 
ATOM   2187 C CA   . PHE A 1 131 ? -1.341  0.206   2.195   1.000 8.775  0 146  PHE A CA   1 ? 
ATOM   2188 C C    . PHE A 1 131 ? -0.907  1.073   3.374   1.000 9.643  0 146  PHE A C    1 ? 
ATOM   2189 O O    . PHE A 1 131 ? 0.294   1.074   3.711   1.000 11.152 0 146  PHE A O    1 ? 
ATOM   2190 C CB   . PHE A 1 131 ? -1.530  1.104   0.958   1.000 9.099  0 146  PHE A CB   1 ? 
ATOM   2191 C CG   . PHE A 1 131 ? -0.305  1.902   0.563   1.000 9.911  0 146  PHE A CG   1 ? 
ATOM   2192 C CD1  . PHE A 1 131 ? 0.798   1.269   0.000   1.000 10.814 0 146  PHE A CD1  1 ? 
ATOM   2193 C CD2  . PHE A 1 131 ? -0.235  3.270   0.774   1.000 11.797 0 146  PHE A CD2  1 ? 
ATOM   2194 C CE1  . PHE A 1 131 ? 1.925   1.979   -0.352  1.000 11.671 0 146  PHE A CE1  1 ? 
ATOM   2195 C CE2  . PHE A 1 131 ? 0.881   3.977   0.373   1.000 12.236 0 146  PHE A CE2  1 ? 
ATOM   2196 C CZ   . PHE A 1 131 ? 1.968   3.315   -0.179  1.000 11.642 0 146  PHE A CZ   1 ? 
ATOM   2197 H H    . PHE A 1 131 ? -3.308  -0.318  1.946   1.000 8.948  0 146  PHE A H    1 c 
ATOM   2198 H HA   . PHE A 1 131 ? -0.644  -0.476  2.007   1.000 8.968  0 146  PHE A HA   1 c 
ATOM   2199 H HB2  . PHE A 1 131 ? -1.795  0.536   0.201   1.000 9.208  0 146  PHE A HB2  1 c 
ATOM   2200 H HB3  . PHE A 1 131 ? -2.269  1.726   1.137   1.000 9.228  0 146  PHE A HB3  1 c 
ATOM   2201 H HD1  . PHE A 1 131 ? 0.777   0.335   -0.132  1.000 10.801 0 146  PHE A HD1  1 c 
ATOM   2202 H HD2  . PHE A 1 131 ? -0.977  3.727   1.136   1.000 11.395 0 146  PHE A HD2  1 c 
ATOM   2203 H HE1  . PHE A 1 131 ? 2.658   1.531   -0.743  1.000 11.474 0 146  PHE A HE1  1 c 
ATOM   2204 H HE2  . PHE A 1 131 ? 0.921   4.909   0.516   1.000 11.962 0 146  PHE A HE2  1 c 
ATOM   2205 H HZ   . PHE A 1 131 ? 2.740   3.799   -0.426  1.000 11.763 0 146  PHE A HZ   1 c 
ATOM   2206 N N    . ILE A 1 132 ? -1.835  1.875   3.932   1.000 9.265  0 147  ILE A N    1 ? 
ATOM   2207 C CA   . ILE A 1 132 ? -1.439  2.799   5.013   1.000 10.228 0 147  ILE A CA   1 ? 
ATOM   2208 C C    . ILE A 1 132 ? -1.184  2.082   6.334   1.000 11.110 0 147  ILE A C    1 ? 
ATOM   2209 O O    . ILE A 1 132 ? -0.149  2.356   6.995   1.000 12.911 0 147  ILE A O    1 ? 
ATOM   2210 C CB   . ILE A 1 132 ? -2.468  3.914   5.155   1.000 11.165 0 147  ILE A CB   1 ? 
ATOM   2211 C CG1  . ILE A 1 132 ? -2.462  4.815   3.909   1.000 12.065 0 147  ILE A CG1  1 ? 
ATOM   2212 C CG2  . ILE A 1 132 ? -2.215  4.680   6.464   1.000 12.595 0 147  ILE A CG2  1 ? 
ATOM   2213 C CD1  . ILE A 1 132 ? -1.205  5.630   3.737   1.000 13.975 0 147  ILE A CD1  1 ? 
ATOM   2214 H H    . ILE A 1 132 ? -2.703  1.856   3.647   1.000 9.572  0 147  ILE A H    1 c 
ATOM   2215 H HA   . ILE A 1 132 ? -0.598  3.214   4.745   1.000 10.413 0 147  ILE A HA   1 c 
ATOM   2216 H HB   . ILE A 1 132 ? -3.351  3.498   5.217   1.000 11.381 0 147  ILE A HB   1 c 
ATOM   2217 H HG12 . ILE A 1 132 ? -2.584  4.255   3.116   1.000 12.248 0 147  ILE A HG12 1 c 
ATOM   2218 H HG13 . ILE A 1 132 ? -3.225  5.426   3.963   1.000 12.263 0 147  ILE A HG13 1 c 
ATOM   2219 H HG21 . ILE A 1 132 ? -2.695  5.525   6.442   1.000 12.154 0 147  ILE A HG21 1 c 
ATOM   2220 H HG22 . ILE A 1 132 ? -1.264  4.855   6.562   1.000 12.141 0 147  ILE A HG22 1 c 
ATOM   2221 H HG23 . ILE A 1 132 ? -2.527  4.154   7.219   1.000 12.149 0 147  ILE A HG23 1 c 
ATOM   2222 H HD11 . ILE A 1 132 ? -1.051  6.176   4.531   1.000 13.360 0 147  ILE A HD11 1 c 
ATOM   2223 H HD12 . ILE A 1 132 ? -1.307  6.211   2.960   1.000 13.350 0 147  ILE A HD12 1 c 
ATOM   2224 H HD13 . ILE A 1 132 ? -0.440  5.040   3.598   1.000 13.330 0 147  ILE A HD13 1 c 
ATOM   2225 N N    . THR A 1 133 ? -2.048  1.148   6.710   1.000 9.999  0 148  THR A N    1 ? 
ATOM   2226 C CA   . THR A 1 133 ? -1.973  0.593   8.057   1.000 10.235 0 148  THR A CA   1 ? 
ATOM   2227 C C    . THR A 1 133 ? -1.075  -0.628  8.109   1.000 10.801 0 148  THR A C    1 ? 
ATOM   2228 O O    . THR A 1 133 ? -0.536  -0.921  9.181   1.000 12.530 0 148  THR A O    1 ? 
ATOM   2229 C CB   . THR A 1 133 ? -3.363  0.223   8.598   1.000 10.431 0 148  THR A CB   1 ? 
ATOM   2230 O OG1  . THR A 1 133 ? -3.947  -0.857  7.855   1.000 10.588 0 148  THR A OG1  1 ? 
ATOM   2231 C CG2  . THR A 1 133 ? -4.296  1.406   8.650   1.000 11.521 0 148  THR A CG2  1 ? 
ATOM   2232 H H    . THR A 1 133 ? -2.693  0.849   6.134   1.000 10.300 0 148  THR A H    1 c 
ATOM   2233 H HA   . THR A 1 133 ? -1.593  1.279   8.647   1.000 10.345 0 148  THR A HA   1 c 
ATOM   2234 H HB   . THR A 1 133 ? -3.244  -0.079  9.530   1.000 10.623 0 148  THR A HB   1 c 
ATOM   2235 H HG1  . THR A 1 133 ? -4.029  -0.626  7.026   0.000 10.590 0 148  THR A HG1  1 c 
ATOM   2236 H HG21 . THR A 1 133 ? -5.144  1.133   9.038   1.000 11.184 0 148  THR A HG21 1 c 
ATOM   2237 H HG22 . THR A 1 133 ? -4.446  1.742   7.750   1.000 11.179 0 148  THR A HG22 1 c 
ATOM   2238 H HG23 . THR A 1 133 ? -3.901  2.107   9.195   1.000 11.184 0 148  THR A HG23 1 c 
ATOM   2239 N N    . GLY A 1 134 ? -0.847  -1.350  7.003   1.000 10.673 0 149  GLY A N    1 ? 
ATOM   2240 C CA   . GLY A 1 134 ? -0.087  -2.576  6.981   1.000 11.412 0 149  GLY A CA   1 ? 
ATOM   2241 C C    . GLY A 1 134 ? 1.099   -2.530  6.024   1.000 10.741 0 149  GLY A C    1 ? 
ATOM   2242 O O    . GLY A 1 134 ? 1.799   -3.516  5.958   1.000 11.639 0 149  GLY A O    1 ? 
ATOM   2243 H H    . GLY A 1 134 ? -1.213  -1.061  6.217   1.000 10.860 0 149  GLY A H    1 c 
ATOM   2244 H HA2  . GLY A 1 134 ? 0.240   -2.769  7.891   1.000 11.087 0 149  GLY A HA2  1 c 
ATOM   2245 H HA3  . GLY A 1 134 ? -0.686  -3.314  6.718   1.000 11.081 0 149  GLY A HA3  1 c 
ATOM   2246 N N    . THR A 1 135 ? 1.265   -1.444  5.259   1.000 10.995 0 150  THR A N    1 ? 
ATOM   2247 C CA   . THR A 1 135 ? 2.272   -1.378  4.197   1.000 11.593 0 150  THR A CA   1 ? 
ATOM   2248 C C    . THR A 1 135 ? 2.258   -2.640  3.323   1.000 11.062 0 150  THR A C    1 ? 
ATOM   2249 O O    . THR A 1 135 ? 3.308   -3.129  2.869   1.000 11.378 0 150  THR A O    1 ? 
ATOM   2250 C CB   . THR A 1 135 ? 3.650   -0.951  4.725   1.000 13.562 0 150  THR A CB   1 ? 
ATOM   2251 O OG1  . THR A 1 135 ? 4.174   -1.906  5.629   1.000 16.161 0 150  THR A OG1  1 ? 
ATOM   2252 C CG2  . THR A 1 135 ? 3.605   0.412   5.371   1.000 14.209 0 150  THR A CG2  1 ? 
ATOM   2253 H H    . THR A 1 135 ? 0.742   -0.709  5.406   1.000 11.062 0 150  THR A H    1 c 
ATOM   2254 H HA   . THR A 1 135 ? 1.983   -0.649  3.609   1.000 11.712 0 150  THR A HA   1 c 
ATOM   2255 H HB   . THR A 1 135 ? 4.263   -0.886  3.954   1.000 13.752 0 150  THR A HB   1 c 
ATOM   2256 H HG1  . THR A 1 135 ? 3.635   -1.994  6.300   0.000 16.150 0 150  THR A HG1  1 c 
ATOM   2257 H HG21 . THR A 1 135 ? 4.499   0.665   5.659   1.000 14.018 0 150  THR A HG21 1 c 
ATOM   2258 H HG22 . THR A 1 135 ? 3.013   0.388   6.142   1.000 14.004 0 150  THR A HG22 1 c 
ATOM   2259 H HG23 . THR A 1 135 ? 3.276   1.064   4.731   1.000 14.047 0 150  THR A HG23 1 c 
ATOM   2260 N N    . LYS A 1 136 ? 1.063   -3.112  2.968   1.000 10.894 0 151  LYS A N    1 ? 
ATOM   2261 C CA   . LYS A 1 136 ? 0.909   -4.288  2.130   1.000 11.276 0 151  LYS A CA   1 ? 
ATOM   2262 C C    . LYS A 1 136 ? -0.137  -4.018  1.056   1.000 9.794  0 151  LYS A C    1 ? 
ATOM   2263 O O    . LYS A 1 136 ? -1.187  -3.456  1.325   1.000 10.151 0 151  LYS A O    1 ? 
ATOM   2264 C CB   . LYS A 1 136 ? 0.453   -5.520  2.921   1.000 14.033 0 151  LYS A CB   1 ? 
ATOM   2265 C CG   . LYS A 1 136 ? 1.573   -6.094  3.760   1.000 18.153 0 151  LYS A CG   1 ? 
ATOM   2266 C CD   . LYS A 1 136 ? 1.069   -7.281  4.569   1.000 22.344 0 151  LYS A CD   1 ? 
ATOM   2267 C CE   . LYS A 1 136 ? 0.392   -6.795  5.774   1.000 27.448 0 151  LYS A CE   1 ? 
ATOM   2268 N NZ   . LYS A 1 136 ? 1.423   -6.339  6.716   1.000 28.952 0 151  LYS A NZ   1 ? 
ATOM   2269 H H    . LYS A 1 136 ? 0.310   -2.680  3.254   1.000 11.013 0 151  LYS A H    1 c 
ATOM   2270 H HA   . LYS A 1 136 ? 1.776   -4.485  1.694   1.000 11.319 0 151  LYS A HA   1 c 
ATOM   2271 H HB2  . LYS A 1 136 ? -0.293  -5.271  3.507   1.000 14.293 0 151  LYS A HB2  1 c 
ATOM   2272 H HB3  . LYS A 1 136 ? 0.136   -6.209  2.299   1.000 14.212 0 151  LYS A HB3  1 c 
ATOM   2273 H HG2  . LYS A 1 136 ? 2.300   -6.383  3.169   1.000 17.991 0 151  LYS A HG2  1 c 
ATOM   2274 H HG3  . LYS A 1 136 ? 1.916   -5.399  4.359   1.000 18.051 0 151  LYS A HG3  1 c 
ATOM   2275 H HD2  . LYS A 1 136 ? 0.439   -7.806  4.030   1.000 22.277 0 151  LYS A HD2  1 c 
ATOM   2276 H HD3  . LYS A 1 136 ? 1.824   -7.855  4.823   1.000 22.440 0 151  LYS A HD3  1 c 
ATOM   2277 H HE2  . LYS A 1 136 ? -0.212  -6.061  5.564   1.000 26.201 0 151  LYS A HE2  1 c 
ATOM   2278 H HE3  . LYS A 1 136 ? -0.109  -7.532  6.162   1.000 26.462 0 151  LYS A HE3  1 c 
ATOM   2279 H HZ1  . LYS A 1 136 ? 1.762   -5.541  6.458   1.000 28.276 0 151  LYS A HZ1  1 c 
ATOM   2280 H HZ2  . LYS A 1 136 ? 2.094   -6.946  6.774   1.000 28.340 0 151  LYS A HZ2  1 c 
ATOM   2281 H HZ3  . LYS A 1 136 ? 1.051   -6.241  7.537   1.000 28.415 0 151  LYS A HZ3  1 c 
ATOM   2282 N N    . LEU A 1 137 ? 0.188   -4.440  -0.173  1.000 8.683  0 152  LEU A N    1 ? 
ATOM   2283 C CA   . LEU A 1 137 ? -0.715  -4.440  -1.317  1.000 8.510  0 152  LEU A CA   1 ? 
ATOM   2284 C C    . LEU A 1 137 ? -0.504  -5.696  -2.127  1.000 8.748  0 152  LEU A C    1 ? 
ATOM   2285 O O    . LEU A 1 137 ? 0.635   -6.150  -2.324  1.000 10.022 0 152  LEU A O    1 ? 
ATOM   2286 C CB   . LEU A 1 137 ? -0.517  -3.205  -2.198  1.000 8.267  0 152  LEU A CB   1 ? 
ATOM   2287 C CG   . LEU A 1 137 ? -1.082  -1.894  -1.646  1.000 8.908  0 152  LEU A CG   1 ? 
ATOM   2288 C CD1  . LEU A 1 137 ? -0.718  -0.740  -2.560  1.000 9.474  0 152  LEU A CD1  1 ? 
ATOM   2289 C CD2  . LEU A 1 137 ? -2.584  -1.972  -1.437  1.000 9.493  0 152  LEU A CD2  1 ? 
ATOM   2290 H H    . LEU A 1 137 ? 1.038   -4.746  -0.307  1.000 8.964  0 152  LEU A H    1 c 
ATOM   2291 H HA   . LEU A 1 137 ? -1.638  -4.445  -0.974  1.000 8.572  0 152  LEU A HA   1 c 
ATOM   2292 H HB2  . LEU A 1 137 ? 0.449   -3.088  -2.349  1.000 8.464  0 152  LEU A HB2  1 c 
ATOM   2293 H HB3  . LEU A 1 137 ? -0.936  -3.380  -3.072  1.000 8.466  0 152  LEU A HB3  1 c 
ATOM   2294 H HG   . LEU A 1 137 ? -0.661  -1.726  -0.764  1.000 8.994  0 152  LEU A HG   1 c 
ATOM   2295 H HD11 . LEU A 1 137 ? 0.249   -0.685  -2.644  1.000 9.301  0 152  LEU A HD11 1 c 
ATOM   2296 H HD12 . LEU A 1 137 ? -1.058  0.090   -2.187  1.000 9.301  0 152  LEU A HD12 1 c 
ATOM   2297 H HD13 . LEU A 1 137 ? -1.110  -0.885  -3.437  1.000 9.298  0 152  LEU A HD13 1 c 
ATOM   2298 H HD21 . LEU A 1 137 ? -2.779  -2.545  -0.676  1.000 9.311  0 152  LEU A HD21 1 c 
ATOM   2299 H HD22 . LEU A 1 137 ? -3.005  -2.337  -2.233  1.000 9.315  0 152  LEU A HD22 1 c 
ATOM   2300 H HD23 . LEU A 1 137 ? -2.935  -1.081  -1.267  1.000 9.316  0 152  LEU A HD23 1 c 
ATOM   2301 N N    . ASP A 1 138 ? -1.604  -6.200  -2.702  1.000 8.431  0 153  ASP A N    1 ? 
ATOM   2302 C CA   . ASP A 1 138 ? -1.540  -7.214  -3.739  1.000 9.100  0 153  ASP A CA   1 ? 
ATOM   2303 C C    . ASP A 1 138 ? -1.192  -6.594  -5.091  1.000 8.911  0 153  ASP A C    1 ? 
ATOM   2304 O O    . ASP A 1 138 ? -1.103  -5.366  -5.221  1.000 8.290  0 153  ASP A O    1 ? 
ATOM   2305 C CB   . ASP A 1 138 ? -2.787  -8.071  -3.725  1.000 8.918  0 153  ASP A CB   1 ? 
ATOM   2306 C CG   . ASP A 1 138 ? -4.084  -7.359  -4.009  1.000 9.300  0 153  ASP A CG   1 ? 
ATOM   2307 O OD1  . ASP A 1 138 ? -4.103  -6.286  -4.627  1.000 9.564  0 153  ASP A OD1  1 ? 
ATOM   2308 O OD2  . ASP A 1 138 ? -5.157  -7.878  -3.544  1.000 11.042 0 153  ASP A OD2  1 ? 
ATOM   2309 H H    . ASP A 1 138 ? -2.424  -5.898  -2.434  1.000 8.657  0 153  ASP A H    1 c 
ATOM   2310 H HA   . ASP A 1 138 ? -0.810  -7.830  -3.505  1.000 8.903  0 153  ASP A HA   1 c 
ATOM   2311 H HB2  . ASP A 1 138 ? -2.686  -8.785  -4.388  1.000 9.098  0 153  ASP A HB2  1 c 
ATOM   2312 H HB3  . ASP A 1 138 ? -2.862  -8.495  -2.845  1.000 9.071  0 153  ASP A HB3  1 c 
ATOM   2313 N N    . SER A 1 139 ? -0.989  -7.419  -6.122  1.000 9.572  0 154  SER A N    1 ? 
ATOM   2314 C CA   . SER A 1 139 ? -0.463  -6.934  -7.387  1.000 10.023 0 154  SER A CA   1 ? 
ATOM   2315 C C    . SER A 1 139 ? -1.299  -5.806  -7.997  1.000 8.697  0 154  SER A C    1 ? 
ATOM   2316 O O    . SER A 1 139 ? -0.833  -4.693  -8.308  1.000 9.091  0 154  SER A O    1 ? 
ATOM   2317 C CB   . SER A 1 139 ? -0.364  -8.057  -8.380  1.000 11.601 0 154  SER A CB   1 ? 
ATOM   2318 O OG   . SER A 1 139 ? -0.092  -7.518  -9.665  1.000 13.205 0 154  SER A OG   1 ? 
ATOM   2319 H H    . SER A 1 139 ? -1.179  -8.309  -6.033  1.000 9.525  0 154  SER A H    1 c 
ATOM   2320 H HA   . SER A 1 139 ? 0.449   -6.585  -7.223  1.000 9.947  0 154  SER A HA   1 c 
ATOM   2321 H HB2  . SER A 1 139 ? 0.353   -8.665  -8.118  1.000 11.583 0 154  SER A HB2  1 c 
ATOM   2322 H HB3  . SER A 1 139 ? -1.204  -8.553  -8.401  1.000 11.561 0 154  SER A HB3  1 c 
ATOM   2323 H HG   . SER A 1 139 ? -0.038  -8.157  -10.217 0.000 13.210 0 154  SER A HG   1 c 
ATOM   2324 N N    . SER A 1 140 ? -2.598  -6.075  -8.195  1.000 8.183  0 155  SER A N    1 ? 
ATOM   2325 C CA   . SER A 1 140 ? -3.459  -5.095  -8.808  1.000 8.007  0 155  SER A CA   1 ? 
ATOM   2326 C C    . SER A 1 140 ? -3.698  -3.933  -7.857  1.000 8.023  0 155  SER A C    1 ? 
ATOM   2327 O O    . SER A 1 140 ? -4.001  -2.829  -8.292  1.000 8.983  0 155  SER A O    1 ? 
ATOM   2328 C CB   . SER A 1 140 ? -4.731  -5.674  -9.378  1.000 8.616  0 155  SER A CB   1 ? 
ATOM   2329 O OG   . SER A 1 140 ? -5.531  -6.301  -8.384  1.000 9.739  0 155  SER A OG   1 ? 
ATOM   2330 H H    . SER A 1 140 ? -2.945  -6.881  -7.942  1.000 8.296  0 155  SER A H    1 c 
ATOM   2331 H HA   . SER A 1 140 ? -2.955  -4.724  -9.578  1.000 8.163  0 155  SER A HA   1 c 
ATOM   2332 H HB2  . SER A 1 140 ? -5.245  -4.961  -9.801  1.000 8.725  0 155  SER A HB2  1 c 
ATOM   2333 H HB3  . SER A 1 140 ? -4.503  -6.328  -10.066 1.000 8.725  0 155  SER A HB3  1 c 
ATOM   2334 H HG   . SER A 1 140 ? -6.229  -6.607  -8.755  0.000 9.750  0 155  SER A HG   1 c 
ATOM   2335 N N    . GLY A 1 141 ? -3.590  -4.181  -6.534  1.000 8.359  0 156  GLY A N    1 ? 
ATOM   2336 C CA   . GLY A 1 141 ? -3.681  -3.131  -5.534  1.000 8.146  0 156  GLY A CA   1 ? 
ATOM   2337 C C    . GLY A 1 141 ? -2.641  -2.037  -5.735  1.000 7.350  0 156  GLY A C    1 ? 
ATOM   2338 O O    . GLY A 1 141 ? -2.911  -0.851  -5.535  1.000 7.763  0 156  GLY A O    1 ? 
ATOM   2339 H H    . GLY A 1 141 ? -3.467  -5.041  -6.251  1.000 8.230  0 156  GLY A H    1 c 
ATOM   2340 H HA2  . GLY A 1 141 ? -4.581  -2.734  -5.570  1.000 8.018  0 156  GLY A HA2  1 c 
ATOM   2341 H HA3  . GLY A 1 141 ? -3.564  -3.531  -4.640  1.000 8.011  0 156  GLY A HA3  1 c 
ATOM   2342 N N    . VAL A 1 142 ? -1.437  -2.445  -6.122  1.000 7.590  0 157  VAL A N    1 ? 
ATOM   2343 C CA   . VAL A 1 142 ? -0.386  -1.459  -6.427  1.000 8.849  0 157  VAL A CA   1 ? 
ATOM   2344 C C    . VAL A 1 142 ? -0.766  -0.604  -7.625  1.000 8.610  0 157  VAL A C    1 ? 
ATOM   2345 O O    . VAL A 1 142 ? -0.636  0.609   -7.602  1.000 8.435  0 157  VAL A O    1 ? 
ATOM   2346 C CB   . VAL A 1 142 ? 0.945   -2.155  -6.679  1.000 9.366  0 157  VAL A CB   1 ? 
ATOM   2347 C CG1  . VAL A 1 142 ? 1.997   -1.200  -7.250  1.000 9.187  0 157  VAL A CG1  1 ? 
ATOM   2348 C CG2  . VAL A 1 142 ? 1.462   -2.817  -5.413  1.000 10.294 0 157  VAL A CG2  1 ? 
ATOM   2349 H H    . VAL A 1 142 ? -1.252  -3.336  -6.198  1.000 7.845  0 157  VAL A H    1 c 
ATOM   2350 H HA   . VAL A 1 142 ? -0.284  -0.874  -5.652  1.000 8.637  0 157  VAL A HA   1 c 
ATOM   2351 H HB   . VAL A 1 142 ? 0.783   -2.860  -7.346  1.000 9.384  0 157  VAL A HB   1 c 
ATOM   2352 H HG11 . VAL A 1 142 ? 1.991   -0.370  -6.743  1.000 9.238  0 157  VAL A HG11 1 c 
ATOM   2353 H HG12 . VAL A 1 142 ? 1.796   -1.011  -8.182  1.000 9.237  0 157  VAL A HG12 1 c 
ATOM   2354 H HG13 . VAL A 1 142 ? 2.876   -1.610  -7.187  1.000 9.249  0 157  VAL A HG13 1 c 
ATOM   2355 H HG21 . VAL A 1 142 ? 2.354   -3.167  -5.571  1.000 10.027 0 157  VAL A HG21 1 c 
ATOM   2356 H HG22 . VAL A 1 142 ? 0.870   -3.546  -5.162  1.000 9.974  0 157  VAL A HG22 1 c 
ATOM   2357 H HG23 . VAL A 1 142 ? 1.493   -2.164  -4.694  1.000 9.997  0 157  VAL A HG23 1 c 
ATOM   2358 N N    . ALA A 1 143 ? -1.307  -1.210  -8.688  1.000 8.570  0 158  ALA A N    1 ? 
ATOM   2359 C CA   . ALA A 1 143 ? -1.735  -0.446  -9.848  1.000 8.356  0 158  ALA A CA   1 ? 
ATOM   2360 C C    . ALA A 1 143 ? -2.818  0.556   -9.460  1.000 8.167  0 158  ALA A C    1 ? 
ATOM   2361 O O    . ALA A 1 143 ? -2.822  1.724   -9.854  1.000 8.631  0 158  ALA A O    1 ? 
ATOM   2362 C CB   . ALA A 1 143 ? -2.213  -1.341  -10.993 1.000 8.124  0 158  ALA A CB   1 ? 
ATOM   2363 H H    . ALA A 1 143 ? -1.408  -2.119  -8.693  1.000 8.524  0 158  ALA A H    1 c 
ATOM   2364 H HA   . ALA A 1 143 ? -0.949  0.075   -10.168 1.000 8.350  0 158  ALA A HA   1 c 
ATOM   2365 H HB1  . ALA A 1 143 ? -1.490  -1.928  -11.273 1.000 8.191  0 158  ALA A HB1  1 c 
ATOM   2366 H HB2  . ALA A 1 143 ? -2.965  -1.880  -10.695 1.000 8.191  0 158  ALA A HB2  1 c 
ATOM   2367 H HB3  . ALA A 1 143 ? -2.490  -0.791  -11.745 1.000 8.191  0 158  ALA A HB3  1 c 
ATOM   2368 N N    . PHE A 1 144 ? -3.803  0.110   -8.685  1.000 8.222  0 159  PHE A N    1 ? 
ATOM   2369 C CA   . PHE A 1 144 ? -4.874  0.995   -8.218  1.000 8.123  0 159  PHE A CA   1 ? 
ATOM   2370 C C    . PHE A 1 144 ? -4.318  2.158   -7.392  1.000 8.379  0 159  PHE A C    1 ? 
ATOM   2371 O O    . PHE A 1 144 ? -4.705  3.317   -7.579  1.000 8.441  0 159  PHE A O    1 ? 
ATOM   2372 C CB   . PHE A 1 144 ? -5.962  0.219   -7.462  1.000 8.738  0 159  PHE A CB   1 ? 
ATOM   2373 C CG   . PHE A 1 144 ? -7.036  1.151   -6.929  1.000 8.501  0 159  PHE A CG   1 ? 
ATOM   2374 C CD1  . PHE A 1 144 ? -8.134  1.511   -7.672  1.000 9.192  0 159  PHE A CD1  1 ? 
ATOM   2375 C CD2  . PHE A 1 144 ? -6.907  1.664   -5.641  1.000 8.793  0 159  PHE A CD2  1 ? 
ATOM   2376 C CE1  . PHE A 1 144 ? -9.053  2.413   -7.187  1.000 9.418  0 159  PHE A CE1  1 ? 
ATOM   2377 C CE2  . PHE A 1 144 ? -7.863  2.541   -5.155  1.000 9.301  0 159  PHE A CE2  1 ? 
ATOM   2378 C CZ   . PHE A 1 144 ? -8.926  2.876   -5.897  1.000 9.394  0 159  PHE A CZ   1 ? 
ATOM   2379 H H    . PHE A 1 144 ? -3.820  -0.770  -8.439  1.000 8.194  0 159  PHE A H    1 c 
ATOM   2380 H HA   . PHE A 1 144 ? -5.303  1.386   -9.026  1.000 8.301  0 159  PHE A HA   1 c 
ATOM   2381 H HB2  . PHE A 1 144 ? -6.371  -0.435  -8.071  1.000 8.542  0 159  PHE A HB2  1 c 
ATOM   2382 H HB3  . PHE A 1 144 ? -5.547  -0.263  -6.712  1.000 8.543  0 159  PHE A HB3  1 c 
ATOM   2383 H HD1  . PHE A 1 144 ? -8.220  1.189   -8.556  1.000 9.078  0 159  PHE A HD1  1 c 
ATOM   2384 H HD2  . PHE A 1 144 ? -6.164  1.427   -5.111  1.000 8.864  0 159  PHE A HD2  1 c 
ATOM   2385 H HE1  . PHE A 1 144 ? -9.812  2.640   -7.701  1.000 9.349  0 159  PHE A HE1  1 c 
ATOM   2386 H HE2  . PHE A 1 144 ? -7.779  2.882   -4.279  1.000 9.199  0 159  PHE A HE2  1 c 
ATOM   2387 H HZ   . PHE A 1 144 ? -9.566  3.476   -5.550  1.000 9.375  0 159  PHE A HZ   1 c 
ATOM   2388 N N    . ALA A 1 145 ? -3.381  1.848   -6.523  1.000 8.690  0 160  ALA A N    1 ? 
ATOM   2389 C CA   . ALA A 1 145 ? -2.769  2.853   -5.666  1.000 8.433  0 160  ALA A CA   1 ? 
ATOM   2390 C C    . ALA A 1 145 ? -1.984  3.896   -6.466  1.000 8.427  0 160  ALA A C    1 ? 
ATOM   2391 O O    . ALA A 1 145 ? -2.030  5.085   -6.121  1.000 9.263  0 160  ALA A O    1 ? 
ATOM   2392 C CB   . ALA A 1 145 ? -1.912  2.196   -4.618  1.000 9.031  0 160  ALA A CB   1 ? 
ATOM   2393 H H    . ALA A 1 145 ? -3.108  0.980   -6.446  1.000 8.554  0 160  ALA A H    1 c 
ATOM   2394 H HA   . ALA A 1 145 ? -3.509  3.334   -5.201  1.000 8.591  0 160  ALA A HA   1 c 
ATOM   2395 H HB1  . ALA A 1 145 ? -2.458  1.607   -4.072  1.000 8.849  0 160  ALA A HB1  1 c 
ATOM   2396 H HB2  . ALA A 1 145 ? -1.211  1.678   -5.047  1.000 8.849  0 160  ALA A HB2  1 c 
ATOM   2397 H HB3  . ALA A 1 145 ? -1.509  2.876   -4.053  1.000 8.849  0 160  ALA A HB3  1 c 
ATOM   2398 N N    . VAL A 1 146 ? -1.358  3.459   -7.553  1.000 8.643  0 161  VAL A N    1 ? 
ATOM   2399 C CA   . VAL A 1 146 ? -0.660  4.391   -8.422  1.000 8.165  0 161  VAL A CA   1 ? 
ATOM   2400 C C    . VAL A 1 146 ? -1.658  5.342   -9.060  1.000 8.316  0 161  VAL A C    1 ? 
ATOM   2401 O O    . VAL A 1 146 ? -1.461  6.561   -9.107  1.000 9.082  0 161  VAL A O    1 ? 
ATOM   2402 C CB   . VAL A 1 146 ? 0.181   3.646   -9.476  1.000 8.026  0 161  VAL A CB   1 ? 
ATOM   2403 C CG1  . VAL A 1 146 ? 0.634   4.579   -10.619 1.000 8.937  0 161  VAL A CG1  1 ? 
ATOM   2404 C CG2  . VAL A 1 146 ? 1.355   2.955   -8.853  1.000 9.233  0 161  VAL A CG2  1 ? 
ATOM   2405 H H    . VAL A 1 146 ? -1.355  2.568   -7.758  1.000 8.479  0 161  VAL A H    1 c 
ATOM   2406 H HA   . VAL A 1 146 ? -0.050  4.918   -7.869  1.000 8.264  0 161  VAL A HA   1 c 
ATOM   2407 H HB   . VAL A 1 146 ? -0.399  2.953   -9.871  1.000 8.436  0 161  VAL A HB   1 c 
ATOM   2408 H HG11 . VAL A 1 146 ? 0.994   5.401   -10.245 1.000 8.661  0 161  VAL A HG11 1 c 
ATOM   2409 H HG12 . VAL A 1 146 ? -0.124  4.787   -11.191 1.000 8.660  0 161  VAL A HG12 1 c 
ATOM   2410 H HG13 . VAL A 1 146 ? 1.322   4.136   -11.145 1.000 8.665  0 161  VAL A HG13 1 c 
ATOM   2411 H HG21 . VAL A 1 146 ? 1.872   2.505   -9.543  1.000 8.855  0 161  VAL A HG21 1 c 
ATOM   2412 H HG22 . VAL A 1 146 ? 1.042   2.302   -8.207  1.000 8.853  0 161  VAL A HG22 1 c 
ATOM   2413 H HG23 . VAL A 1 146 ? 1.914   3.610   -8.404  1.000 8.868  0 161  VAL A HG23 1 c 
ATOM   2414 N N    . VAL A 1 147 ? -2.783  4.831   -9.528  1.000 8.428  0 162  VAL A N    1 ? 
ATOM   2415 C CA   . VAL A 1 147 ? -3.813  5.664   -10.117 1.000 8.219  0 162  VAL A CA   1 ? 
ATOM   2416 C C    . VAL A 1 147 ? -4.387  6.625   -9.070  1.000 8.842  0 162  VAL A C    1 ? 
ATOM   2417 O O    . VAL A 1 147 ? -4.609  7.819   -9.348  1.000 9.838  0 162  VAL A O    1 ? 
ATOM   2418 C CB   . VAL A 1 147 ? -4.909  4.847   -10.825 1.000 8.799  0 162  VAL A CB   1 ? 
ATOM   2419 C CG1  . VAL A 1 147 ? -6.030  5.730   -11.309 1.000 8.947  0 162  VAL A CG1  1 ? 
ATOM   2420 C CG2  . VAL A 1 147 ? -4.275  4.029   -11.931 1.000 8.553  0 162  VAL A CG2  1 ? 
ATOM   2421 H H    . VAL A 1 147 ? -2.922  3.929   -9.477  1.000 8.361  0 162  VAL A H    1 c 
ATOM   2422 H HA   . VAL A 1 147 ? -3.380  6.211   -10.801 1.000 8.481  0 162  VAL A HA   1 c 
ATOM   2423 H HB   . VAL A 1 147 ? -5.281  4.221   -10.160 1.000 8.670  0 162  VAL A HB   1 c 
ATOM   2424 H HG11 . VAL A 1 147 ? -5.659  6.500   -11.772 1.000 8.947  0 162  VAL A HG11 1 c 
ATOM   2425 H HG12 . VAL A 1 147 ? -6.560  6.032   -10.551 1.000 8.913  0 162  VAL A HG12 1 c 
ATOM   2426 H HG13 . VAL A 1 147 ? -6.598  5.228   -11.919 1.000 8.913  0 162  VAL A HG13 1 c 
ATOM   2427 H HG21 . VAL A 1 147 ? -4.968  3.553   -12.420 1.000 8.624  0 162  VAL A HG21 1 c 
ATOM   2428 H HG22 . VAL A 1 147 ? -3.653  3.389   -11.550 1.000 8.622  0 162  VAL A HG22 1 c 
ATOM   2429 H HG23 . VAL A 1 147 ? -3.799  4.620   -12.539 1.000 8.623  0 162  VAL A HG23 1 c 
ATOM   2430 N N    . GLY A 1 148 ? -4.668  6.141   -7.842  1.000 9.082  0 163  GLY A N    1 ? 
ATOM   2431 C CA   . GLY A 1 148 ? -5.193  7.020   -6.781  1.000 9.323  0 163  GLY A CA   1 ? 
ATOM   2432 C C    . GLY A 1 148 ? -4.201  8.126   -6.423  1.000 9.174  0 163  GLY A C    1 ? 
ATOM   2433 O O    . GLY A 1 148 ? -4.620  9.276   -6.259  1.000 10.211 0 163  GLY A O    1 ? 
ATOM   2434 H H    . GLY A 1 148 ? -4.538  5.255   -7.661  1.000 9.067  0 163  GLY A H    1 c 
ATOM   2435 H HA2  . GLY A 1 148 ? -6.040  7.422   -7.085  1.000 9.236  0 163  GLY A HA2  1 c 
ATOM   2436 H HA3  . GLY A 1 148 ? -5.385  6.478   -5.980  1.000 9.233  0 163  GLY A HA3  1 c 
ATOM   2437 N N    . ALA A 1 149 ? -2.947  7.765   -6.336  1.000 8.643  0 164  ALA A N    1 ? 
ATOM   2438 C CA   . ALA A 1 149 ? -1.879  8.745   -6.078  1.000 10.058 0 164  ALA A CA   1 ? 
ATOM   2439 C C    . ALA A 1 149 ? -1.808  9.788   -7.192  1.000 11.416 0 164  ALA A C    1 ? 
ATOM   2440 O O    . ALA A 1 149 ? -1.625  10.976  -6.908  1.000 11.388 0 164  ALA A O    1 ? 
ATOM   2441 C CB   . ALA A 1 149 ? -0.554  8.072   -5.906  1.000 10.981 0 164  ALA A CB   1 ? 
ATOM   2442 H H    . ALA A 1 149 ? -2.724  6.883   -6.429  1.000 9.082  0 164  ALA A H    1 c 
ATOM   2443 H HA   . ALA A 1 149 ? -2.104  9.221   -5.232  1.000 10.158 0 164  ALA A HA   1 c 
ATOM   2444 H HB1  . ALA A 1 149 ? -0.591  7.466   -5.147  1.000 10.722 0 164  ALA A HB1  1 c 
ATOM   2445 H HB2  . ALA A 1 149 ? -0.337  7.567   -6.708  1.000 10.708 0 164  ALA A HB2  1 c 
ATOM   2446 H HB3  . ALA A 1 149 ? 0.135   8.739   -5.751  1.000 10.731 0 164  ALA A HB3  1 c 
ATOM   2447 N N    . CYS A 1 150 ? -1.875  9.351   -8.454  1.000 9.480  0 165  CYS A N    1 ? 
ATOM   2448 C CA   . CYS A 1 150 ? -1.862  10.290  -9.579  1.000 10.502 0 165  CYS A CA   1 ? 
ATOM   2449 C C    . CYS A 1 150 ? -3.066  11.203  -9.550  1.000 10.461 0 165  CYS A C    1 ? 
ATOM   2450 O O    . CYS A 1 150 ? -2.918  12.423  -9.769  1.000 10.893 0 165  CYS A O    1 ? 
ATOM   2451 C CB   . CYS A 1 150 ? -1.777  9.546   -10.907 1.000 11.454 0 165  CYS A CB   1 ? 
ATOM   2452 S SG   . CYS A 1 150 ? -0.165  8.781   -11.209 1.000 10.306 0 165  CYS A SG   1 ? 
ATOM   2453 H H    . CYS A 1 150 ? -1.924  8.454   -8.623  1.000 10.143 0 165  CYS A H    1 c 
ATOM   2454 H HA   . CYS A 1 150 ? -1.049  10.850  -9.494  1.000 10.465 0 165  CYS A HA   1 c 
ATOM   2455 H HB2  . CYS A 1 150 ? -2.463  8.843   -10.925 1.000 10.995 0 165  CYS A HB2  1 c 
ATOM   2456 H HB3  . CYS A 1 150 ? -1.966  10.172  -11.641 1.000 11.015 0 165  CYS A HB3  1 c 
ATOM   2457 H HG   . CYS A 1 150 ? -0.419  8.297   -12.291 0.000 10.310 0 165  CYS A HG   1 c 
ATOM   2458 N N    . GLN A 1 151 ? -4.240  10.720  -9.200  1.000 11.139 0 166  GLN A N    1 ? 
ATOM   2459 C CA   . GLN A 1 151 ? -5.386  11.603  -9.067  1.000 11.434 0 166  GLN A CA   1 ? 
ATOM   2460 C C    . GLN A 1 151 ? -5.132  12.613  -7.955  1.000 12.272 0 166  GLN A C    1 ? 
ATOM   2461 O O    . GLN A 1 151 ? -5.414  13.815  -8.153  1.000 13.920 0 166  GLN A O    1 ? 
ATOM   2462 C CB   . GLN A 1 151 ? -6.675  10.830  -8.805  1.000 10.709 0 166  GLN A CB   1 ? 
ATOM   2463 C CG   . GLN A 1 151 ? -7.873  11.724  -8.585  1.000 11.574 0 166  GLN A CG   1 ? 
ATOM   2464 C CD   . GLN A 1 151 ? -9.116  10.996  -8.148  1.000 11.702 0 166  GLN A CD   1 ? 
ATOM   2465 O OE1  . GLN A 1 151 ? -9.083  10.186  -7.210  1.000 12.377 0 166  GLN A OE1  1 ? 
ATOM   2466 N NE2  . GLN A 1 151 ? -10.233 11.316  -8.781  1.000 11.995 0 166  GLN A NE2  1 ? 
ATOM   2467 H H    . GLN A 1 151 ? -4.343  9.825   -9.044  1.000 11.022 0 166  GLN A H    1 c 
ATOM   2468 H HA   . GLN A 1 151 ? -5.494  12.098  -9.919  1.000 11.393 0 166  GLN A HA   1 c 
ATOM   2469 H HB2  . GLN A 1 151 ? -6.852  10.241  -9.568  1.000 11.067 0 166  GLN A HB2  1 c 
ATOM   2470 H HB3  . GLN A 1 151 ? -6.549  10.265  -8.014  1.000 11.072 0 166  GLN A HB3  1 c 
ATOM   2471 H HG2  . GLN A 1 151 ? -7.656  12.391  -7.900  1.000 11.427 0 166  GLN A HG2  1 c 
ATOM   2472 H HG3  . GLN A 1 151 ? -8.066  12.208  -9.416  1.000 11.459 0 166  GLN A HG3  1 c 
ATOM   2473 H HE21 . GLN A 1 151 ? -10.200 11.731  -9.566  1.000 11.995 0 166  GLN A HE21 1 c 
ATOM   2474 H HE22 . GLN A 1 151 ? -11.018 11.112  -8.418  1.000 11.928 0 166  GLN A HE22 1 c 
ATOM   2475 N N    . ALA A 1 152 ? -4.563  12.185  -6.846  1.000 12.839 0 167  ALA A N    1 ? 
ATOM   2476 C CA   . ALA A 1 152 ? -4.343  13.087  -5.719  1.000 15.098 0 167  ALA A CA   1 ? 
ATOM   2477 C C    . ALA A 1 152 ? -3.385  14.202  -6.131  1.000 14.692 0 167  ALA A C    1 ? 
ATOM   2478 O O    . ALA A 1 152 ? -3.539  15.365  -5.698  1.000 17.462 0 167  ALA A O    1 ? 
ATOM   2479 C CB   . ALA A 1 152 ? -3.819  12.323  -4.562  1.000 15.006 0 167  ALA A CB   1 ? 
ATOM   2480 H H    . ALA A 1 152 ? -4.305  11.311  -6.773  1.000 13.156 0 167  ALA A H    1 c 
ATOM   2481 H HA   . ALA A 1 152 ? -5.217  13.500  -5.472  1.000 14.528 0 167  ALA A HA   1 c 
ATOM   2482 H HB1  . ALA A 1 152 ? -4.438  11.610  -4.334  1.000 15.067 0 167  ALA A HB1  1 c 
ATOM   2483 H HB2  . ALA A 1 152 ? -2.956  11.939  -4.788  1.000 15.050 0 167  ALA A HB2  1 c 
ATOM   2484 H HB3  . ALA A 1 152 ? -3.716  12.915  -3.798  1.000 15.194 0 167  ALA A HB3  1 c 
ATOM   2485 N N    . LEU A 1 153 ? -2.428  13.890  -7.019  1.000 12.875 0 168  LEU A N    1 ? 
ATOM   2486 C CA   . LEU A 1 153 ? -1.425  14.843  -7.518  1.000 15.155 0 168  LEU A CA   1 ? 
ATOM   2487 C C    . LEU A 1 153 ? -1.987  15.745  -8.609  1.000 16.272 0 168  LEU A C    1 ? 
ATOM   2488 O O    . LEU A 1 153 ? -1.251  16.640  -9.067  1.000 19.582 0 168  LEU A O    1 ? 
ATOM   2489 C CB   . LEU A 1 153 ? -0.225  14.063  -8.054  1.000 14.076 0 168  LEU A CB   1 ? 
ATOM   2490 C CG   . LEU A 1 153 ? 0.694   13.441  -7.017  1.000 14.351 0 168  LEU A CG   1 ? 
ATOM   2491 C CD1  . LEU A 1 153 ? 1.649   12.459  -7.643  1.000 15.640 0 168  LEU A CD1  1 ? 
ATOM   2492 C CD2  . LEU A 1 153 ? 1.449   14.555  -6.283  1.000 17.337 0 168  LEU A CD2  1 ? 
ATOM   2493 H H    . LEU A 1 153 ? -2.388  13.030  -7.326  1.000 13.782 0 168  LEU A H    1 c 
ATOM   2494 H HA   . LEU A 1 153 ? -1.134  15.411  -6.761  1.000 14.715 0 168  LEU A HA   1 c 
ATOM   2495 H HB2  . LEU A 1 153 ? -0.562  13.346  -8.639  1.000 14.392 0 168  LEU A HB2  1 c 
ATOM   2496 H HB3  . LEU A 1 153 ? 0.310   14.669  -8.616  1.000 14.440 0 168  LEU A HB3  1 c 
ATOM   2497 H HG   . LEU A 1 153 ? 0.136   12.956  -6.357  1.000 15.026 0 168  LEU A HG   1 c 
ATOM   2498 H HD11 . LEU A 1 153 ? 1.147   11.747  -8.074  1.000 15.244 0 168  LEU A HD11 1 c 
ATOM   2499 H HD12 . LEU A 1 153 ? 2.222   12.080  -6.956  1.000 15.244 0 168  LEU A HD12 1 c 
ATOM   2500 H HD13 . LEU A 1 153 ? 2.196   12.914  -8.305  1.000 15.244 0 168  LEU A HD13 1 c 
ATOM   2501 H HD21 . LEU A 1 153 ? 0.826   15.076  -5.751  1.000 16.379 0 168  LEU A HD21 1 c 
ATOM   2502 H HD22 . LEU A 1 153 ? 1.884   15.135  -6.931  1.000 16.383 0 168  LEU A HD22 1 c 
ATOM   2503 H HD23 . LEU A 1 153 ? 2.121   14.162  -5.701  1.000 16.393 0 168  LEU A HD23 1 c 
ATOM   2504 N N    . GLY A 1 154 ? -3.206  15.521  -9.108  1.000 13.045 0 169  GLY A N    1 ? 
ATOM   2505 C CA   . GLY A 1 154 ? -3.816  16.311  -10.174 1.000 14.304 0 169  GLY A CA   1 ? 
ATOM   2506 C C    . GLY A 1 154 ? -3.579  15.805  -11.590 1.000 16.093 0 169  GLY A C    1 ? 
ATOM   2507 O O    . GLY A 1 154 ? -3.824  16.530  -12.566 1.000 17.359 0 169  GLY A O    1 ? 
ATOM   2508 H H    . GLY A 1 154 ? -3.689  14.825  -8.769  1.000 14.032 0 169  GLY A H    1 c 
ATOM   2509 H HA2  . GLY A 1 154 ? -4.786  16.348  -10.012 1.000 14.441 0 169  GLY A HA2  1 c 
ATOM   2510 H HA3  . GLY A 1 154 ? -3.477  17.235  -10.109 1.000 14.418 0 169  GLY A HA3  1 c 
ATOM   2511 N N    . LEU A 1 155 ? -3.176  14.540  -11.731 1.000 13.830 0 170  LEU A N    1 ? 
ATOM   2512 C CA   . LEU A 1 155 ? -2.807  13.973  -13.021 1.000 14.548 0 170  LEU A CA   1 ? 
ATOM   2513 C C    . LEU A 1 155 ? -4.013  13.249  -13.643 1.000 15.362 0 170  LEU A C    1 ? 
ATOM   2514 O O    . LEU A 1 155 ? -4.189  12.002  -13.535 1.000 17.250 0 170  LEU A O    1 ? 
ATOM   2515 C CB   . LEU A 1 155 ? -1.634  13.049  -12.852 1.000 14.029 0 170  LEU A CB   1 ? 
ATOM   2516 C CG   . LEU A 1 155 ? -0.460  13.613  -12.080 1.000 13.811 0 170  LEU A CG   1 ? 
ATOM   2517 C CD1  . LEU A 1 155 ? 0.648   12.583  -11.937 1.000 15.098 0 170  LEU A CD1  1 ? 
ATOM   2518 C CD2  . LEU A 1 155 ? 0.070   14.889  -12.715 1.000 15.623 0 170  LEU A CD2  1 ? 
ATOM   2519 H H    . LEU A 1 155 ? -3.138  14.002  -10.993 1.000 14.487 0 170  LEU A H    1 c 
ATOM   2520 H HA   . LEU A 1 155 ? -2.545  14.713  -13.624 1.000 14.488 0 170  LEU A HA   1 c 
ATOM   2521 H HB2  . LEU A 1 155 ? -1.945  12.238  -12.390 1.000 14.091 0 170  LEU A HB2  1 c 
ATOM   2522 H HB3  . LEU A 1 155 ? -1.319  12.784  -13.747 1.000 14.088 0 170  LEU A HB3  1 c 
ATOM   2523 H HG   . LEU A 1 155 ? -0.775  13.841  -11.167 1.000 14.408 0 170  LEU A HG   1 c 
ATOM   2524 H HD11 . LEU A 1 155 ? 0.309   11.805  -11.464 1.000 14.699 0 170  LEU A HD11 1 c 
ATOM   2525 H HD12 . LEU A 1 155 ? 1.388   12.968  -11.438 1.000 14.676 0 170  LEU A HD12 1 c 
ATOM   2526 H HD13 . LEU A 1 155 ? 0.959   12.315  -12.819 1.000 14.699 0 170  LEU A HD13 1 c 
ATOM   2527 H HD21 . LEU A 1 155 ? -0.617  15.576  -12.697 1.000 15.106 0 170  LEU A HD21 1 c 
ATOM   2528 H HD22 . LEU A 1 155 ? 0.320   14.702  -13.634 1.000 15.228 0 170  LEU A HD22 1 c 
ATOM   2529 H HD23 . LEU A 1 155 ? 0.849   15.197  -12.224 1.000 15.152 0 170  LEU A HD23 1 c 
ATOM   2530 N N    . ARG A 1 156 ? -4.876  14.037  -14.285 1.000 14.741 0 171  ARG A N    1 ? 
ATOM   2531 C CA   . ARG A 1 156 ? -6.203  13.614  -14.716 1.000 15.642 0 171  ARG A CA   1 ? 
ATOM   2532 C C    . ARG A 1 156 ? -6.111  12.545  -15.814 1.000 14.689 0 171  ARG A C    1 ? 
ATOM   2533 O O    . ARG A 1 156 ? -7.124  11.884  -16.084 1.000 15.094 0 171  ARG A O    1 ? 
ATOM   2534 C CB   . ARG A 1 156 ? -7.040  14.808  -15.201 1.000 22.561 0 171  ARG A CB   1 ? 
ATOM   2535 C CG   . ARG A 1 156 ? -7.354  15.818  -14.100 1.000 30.017 0 171  ARG A CG   1 ? 
ATOM   2536 C CD   . ARG A 1 156 ? -8.377  16.867  -14.536 1.000 38.344 0 171  ARG A CD   1 ? 
ATOM   2537 N NE   . ARG A 1 156 ? -9.757  16.368  -14.462 1.000 48.875 0 171  ARG A NE   1 ? 
ATOM   2538 C CZ   . ARG A 1 156 ? -10.844 17.131  -14.574 1.000 58.093 0 171  ARG A CZ   1 ? 
ATOM   2539 N NH1  . ARG A 1 156 ? -12.052 16.593  -14.520 1.000 61.291 0 171  ARG A NH1  1 ? 
ATOM   2540 N NH2  . ARG A 1 156 ? -10.721 18.439  -14.738 1.000 64.054 0 171  ARG A NH2  1 ? 
ATOM   2541 H H    . ARG A 1 156 ? -4.621  14.896  -14.469 1.000 15.121 0 171  ARG A H    1 c 
ATOM   2542 H HA   . ARG A 1 156 ? -6.661  13.215  -13.939 1.000 16.407 0 171  ARG A HA   1 c 
ATOM   2543 H HB2  . ARG A 1 156 ? -6.557  15.263  -15.923 1.000 22.212 0 171  ARG A HB2  1 c 
ATOM   2544 H HB3  . ARG A 1 156 ? -7.884  14.472  -15.571 1.000 22.117 0 171  ARG A HB3  1 c 
ATOM   2545 H HG2  . ARG A 1 156 ? -7.700  15.342  -13.315 1.000 29.706 0 171  ARG A HG2  1 c 
ATOM   2546 H HG3  . ARG A 1 156 ? -6.525  16.273  -13.835 1.000 29.732 0 171  ARG A HG3  1 c 
ATOM   2547 H HD2  . ARG A 1 156 ? -8.289  17.655  -13.961 1.000 38.534 0 171  ARG A HD2  1 c 
ATOM   2548 H HD3  . ARG A 1 156 ? -8.183  17.141  -15.455 1.000 38.453 0 171  ARG A HD3  1 c 
ATOM   2549 H HE   . ARG A 1 156 ? -9.874  15.513  -14.337 1.000 48.155 0 171  ARG A HE   1 c 
ATOM   2550 H HH11 . ARG A 1 156 ? -12.759 17.083  -14.726 1.000 60.267 0 171  ARG A HH11 1 c 
ATOM   2551 H HH12 . ARG A 1 156 ? -12.150 15.748  -14.279 1.000 60.084 0 171  ARG A HH12 1 c 
ATOM   2552 H HH21 . ARG A 1 156 ? -11.175 18.990  -14.214 1.000 62.112 0 171  ARG A HH21 1 c 
ATOM   2553 H HH22 . ARG A 1 156 ? -10.190 18.757  -15.371 1.000 61.965 0 171  ARG A HH22 1 c 
ATOM   2554 N N    . ASP A 1 157 ? -4.960  12.453  -16.509 1.000 11.772 0 172  ASP A N    1 ? 
ATOM   2555 C CA   . ASP A 1 157 ? -4.822  11.577  -17.662 1.000 11.112 0 172  ASP A CA   1 ? 
ATOM   2556 C C    . ASP A 1 157 ? -4.409  10.148  -17.271 1.000 10.612 0 172  ASP A C    1 ? 
ATOM   2557 O O    . ASP A 1 157 ? -4.449  9.268   -18.146 1.000 11.268 0 172  ASP A O    1 ? 
ATOM   2558 C CB   . ASP A 1 157 ? -3.780  12.117  -18.648 1.000 10.868 0 172  ASP A CB   1 ? 
ATOM   2559 C CG   . ASP A 1 157 ? -2.385  12.214  -18.061 1.000 11.824 0 172  ASP A CG   1 ? 
ATOM   2560 O OD1  . ASP A 1 157 ? -2.254  12.747  -16.938 1.000 11.697 0 172  ASP A OD1  1 ? 
ATOM   2561 O OD2  . ASP A 1 157 ? -1.414  11.811  -18.729 1.000 12.450 0 172  ASP A OD2  1 ? 
ATOM   2562 H H    . ASP A 1 157 ? -4.244  12.964  -16.261 1.000 12.293 0 172  ASP A H    1 c 
ATOM   2563 H HA   . ASP A 1 157 ? -5.687  11.538  -18.130 1.000 11.135 0 172  ASP A HA   1 c 
ATOM   2564 H HB2  . ASP A 1 157 ? -3.747  11.532  -19.433 1.000 11.145 0 172  ASP A HB2  1 c 
ATOM   2565 H HB3  . ASP A 1 157 ? -4.053  13.010  -18.945 1.000 11.138 0 172  ASP A HB3  1 c 
ATOM   2566 N N    . VAL A 1 158 ? -4.019  9.888   -16.026 1.000 9.514  0 173  VAL A N    1 ? 
ATOM   2567 C CA   . VAL A 1 158 ? -3.520  8.568   -15.649 1.000 9.373  0 173  VAL A CA   1 ? 
ATOM   2568 C C    . VAL A 1 158 ? -4.710  7.715   -15.235 1.000 10.041 0 173  VAL A C    1 ? 
ATOM   2569 O O    . VAL A 1 158 ? -5.421  8.077   -14.296 1.000 11.669 0 173  VAL A O    1 ? 
ATOM   2570 C CB   . VAL A 1 158 ? -2.475  8.621   -14.544 1.000 10.112 0 173  VAL A CB   1 ? 
ATOM   2571 C CG1  . VAL A 1 158 ? -2.055  7.229   -14.178 1.000 11.642 0 173  VAL A CG1  1 ? 
ATOM   2572 C CG2  . VAL A 1 158 ? -1.270  9.472   -14.948 1.000 9.893  0 173  VAL A CG2  1 ? 
ATOM   2573 H H    . VAL A 1 158 ? -4.058  10.543  -15.390 1.000 9.768  0 173  VAL A H    1 c 
ATOM   2574 H HA   . VAL A 1 158 ? -3.107  8.163   -16.434 1.000 9.667  0 173  VAL A HA   1 c 
ATOM   2575 H HB   . VAL A 1 158 ? -2.899  9.036   -13.756 1.000 10.198 0 173  VAL A HB   1 c 
ATOM   2576 H HG11 . VAL A 1 158 ? -1.867  6.722   -14.986 1.000 11.134 0 173  VAL A HG11 1 c 
ATOM   2577 H HG12 . VAL A 1 158 ? -2.767  6.792   -13.681 1.000 11.147 0 173  VAL A HG12 1 c 
ATOM   2578 H HG13 . VAL A 1 158 ? -1.255  7.266   -13.626 1.000 11.139 0 173  VAL A HG13 1 c 
ATOM   2579 H HG21 . VAL A 1 158 ? -0.607  9.454   -14.237 1.000 9.964  0 173  VAL A HG21 1 c 
ATOM   2580 H HG22 . VAL A 1 158 ? -1.554  10.389  -15.100 1.000 9.956  0 173  VAL A HG22 1 c 
ATOM   2581 H HG23 . VAL A 1 158 ? -0.879  9.115   -15.763 1.000 9.958  0 173  VAL A HG23 1 c 
ATOM   2582 N N    . HIS A 1 159 ? -4.893  6.578   -15.895 1.000 8.657  0 174  HIS A N    1 ? 
ATOM   2583 C CA   . HIS A 1 159 ? -6.041  5.712   -15.663 1.000 8.222  0 174  HIS A CA   1 ? 
ATOM   2584 C C    . HIS A 1 159 ? -5.618  4.245   -15.606 1.000 7.757  0 174  HIS A C    1 ? 
ATOM   2585 O O    . HIS A 1 159 ? -4.565  3.811   -16.096 1.000 8.656  0 174  HIS A O    1 ? 
ATOM   2586 C CB   . HIS A 1 159 ? -7.068  5.855   -16.783 1.000 8.515  0 174  HIS A CB   1 ? 
ATOM   2587 C CG   . HIS A 1 159 ? -7.833  7.098   -16.658 1.000 9.866  0 174  HIS A CG   1 ? 
ATOM   2588 N ND1  . HIS A 1 159 ? -8.705  7.289   -15.611 1.000 11.665 0 174  HIS A ND1  1 ? 
ATOM   2589 C CD2  . HIS A 1 159 ? -7.805  8.236   -17.380 1.000 12.637 0 174  HIS A CD2  1 ? 
ATOM   2590 C CE1  . HIS A 1 159 ? -9.180  8.553   -15.716 1.000 12.723 0 174  HIS A CE1  1 ? 
ATOM   2591 N NE2  . HIS A 1 159 ? -8.687  9.102   -16.808 1.000 14.243 0 174  HIS A NE2  1 ? 
ATOM   2592 H H    . HIS A 1 159 ? -4.277  6.324   -16.520 1.000 8.868  0 174  HIS A H    1 c 
ATOM   2593 H HA   . HIS A 1 159 ? -6.455  5.953   -14.799 1.000 8.314  0 174  HIS A HA   1 c 
ATOM   2594 H HB2  . HIS A 1 159 ? -6.602  5.847   -17.647 1.000 8.748  0 174  HIS A HB2  1 c 
ATOM   2595 H HB3  . HIS A 1 159 ? -7.683  5.091   -16.750 1.000 8.750  0 174  HIS A HB3  1 c 
ATOM   2596 H HD1  . HIS A 1 159 ? -8.863  6.709   -14.966 0.000 11.660 0 174  HIS A HD1  1 c 
ATOM   2597 H HD2  . HIS A 1 159 ? -7.309  8.394   -18.159 1.000 12.274 0 174  HIS A HD2  1 c 
ATOM   2598 H HE1  . HIS A 1 159 ? -9.829  8.936   -15.156 1.000 12.786 0 174  HIS A HE1  1 c 
ATOM   2599 H HE2  . HIS A 1 159 ? -8.853  9.916   -17.088 0.000 14.250 0 174  HIS A HE2  1 c 
ATOM   2600 N N    . LEU A 1 160 ? -6.428  3.478   -14.890 1.000 7.492  0 175  LEU A N    1 ? 
ATOM   2601 C CA   . LEU A 1 160 ? -6.229  2.039   -14.710 1.000 7.275  0 175  LEU A CA   1 ? 
ATOM   2602 C C    . LEU A 1 160 ? -6.570  1.274   -15.991 1.000 6.788  0 175  LEU A C    1 ? 
ATOM   2603 O O    . LEU A 1 160 ? -7.635  1.488   -16.575 1.000 7.948  0 175  LEU A O    1 ? 
ATOM   2604 C CB   . LEU A 1 160 ? -7.125  1.570   -13.536 1.000 7.226  0 175  LEU A CB   1 ? 
ATOM   2605 C CG   . LEU A 1 160 ? -6.910  0.137   -13.043 1.000 7.357  0 175  LEU A CG   1 ? 
ATOM   2606 C CD1  . LEU A 1 160 ? -5.524  -0.036  -12.469 1.000 8.275  0 175  LEU A CD1  1 ? 
ATOM   2607 C CD2  . LEU A 1 160 ? -7.978  -0.079  -11.968 1.000 7.604  0 175  LEU A CD2  1 ? 
ATOM   2608 H H    . LEU A 1 160 ? -7.153  3.865   -14.489 1.000 7.514  0 175  LEU A H    1 c 
ATOM   2609 H HA   . LEU A 1 160 ? -5.279  1.883   -14.481 1.000 7.239  0 175  LEU A HA   1 c 
ATOM   2610 H HB2  . LEU A 1 160 ? -6.980  2.182   -12.778 1.000 7.269  0 175  LEU A HB2  1 c 
ATOM   2611 H HB3  . LEU A 1 160 ? -8.065  1.665   -13.813 1.000 7.271  0 175  LEU A HB3  1 c 
ATOM   2612 H HG   . LEU A 1 160 ? -7.052  -0.497  -13.793 1.000 7.536  0 175  LEU A HG   1 c 
ATOM   2613 H HD11 . LEU A 1 160 ? -4.865  0.035   -13.179 1.000 7.980  0 175  LEU A HD11 1 c 
ATOM   2614 H HD12 . LEU A 1 160 ? -5.453  -0.911  -12.050 1.000 7.988  0 175  LEU A HD12 1 c 
ATOM   2615 H HD13 . LEU A 1 160 ? -5.359  0.654   -11.804 1.000 7.988  0 175  LEU A HD13 1 c 
ATOM   2616 H HD21 . LEU A 1 160 ? -8.861  0.012   -12.363 1.000 7.528  0 175  LEU A HD21 1 c 
ATOM   2617 H HD22 . LEU A 1 160 ? -7.870  0.583   -11.264 1.000 7.527  0 175  LEU A HD22 1 c 
ATOM   2618 H HD23 . LEU A 1 160 ? -7.883  -0.970  -11.591 1.000 7.529  0 175  LEU A HD23 1 c 
ATOM   2619 N N    . ALA A 1 161 ? -5.652  0.386   -16.359 1.000 7.620  0 176  ALA A N    1 ? 
ATOM   2620 C CA   . ALA A 1 161 ? -5.892  -0.539  -17.454 1.000 7.621  0 176  ALA A CA   1 ? 
ATOM   2621 C C    . ALA A 1 161 ? -5.969  -1.960  -16.864 1.000 7.355  0 176  ALA A C    1 ? 
ATOM   2622 O O    . ALA A 1 161 ? -5.176  -2.315  -15.997 1.000 8.160  0 176  ALA A O    1 ? 
ATOM   2623 C CB   . ALA A 1 161 ? -4.809  -0.457  -18.476 1.000 8.130  0 176  ALA A CB   1 ? 
ATOM   2624 H H    . ALA A 1 161 ? -4.851  0.352   -15.921 1.000 7.411  0 176  ALA A H    1 c 
ATOM   2625 H HA   . ALA A 1 161 ? -6.766  -0.319  -17.875 1.000 7.671  0 176  ALA A HA   1 c 
ATOM   2626 H HB1  . ALA A 1 161 ? -4.768  0.444   -18.836 1.000 7.990  0 176  ALA A HB1  1 c 
ATOM   2627 H HB2  . ALA A 1 161 ? -3.956  -0.677  -18.066 1.000 7.978  0 176  ALA A HB2  1 c 
ATOM   2628 H HB3  . ALA A 1 161 ? -4.990  -1.083  -19.196 1.000 7.978  0 176  ALA A HB3  1 c 
ATOM   2629 N N    . LEU A 1 162 ? -6.927  -2.764  -17.341 1.000 7.318  0 177  LEU A N    1 ? 
ATOM   2630 C CA   . LEU A 1 162 ? -7.191  -4.085  -16.763 1.000 7.231  0 177  LEU A CA   1 ? 
ATOM   2631 C C    . LEU A 1 162 ? -7.326  -5.134  -17.861 1.000 7.378  0 177  LEU A C    1 ? 
ATOM   2632 O O    . LEU A 1 162 ? -8.123  -4.946  -18.790 1.000 7.556  0 177  LEU A O    1 ? 
ATOM   2633 C CB   . LEU A 1 162 ? -8.490  -4.110  -15.962 1.000 7.162  0 177  LEU A CB   1 ? 
ATOM   2634 C CG   . LEU A 1 162 ? -8.552  -3.118  -14.781 1.000 9.067  0 177  LEU A CG   1 ? 
ATOM   2635 C CD1  . LEU A 1 162 ? -9.954  -3.013  -14.249 1.000 8.890  0 177  LEU A CD1  1 ? 
ATOM   2636 C CD2  . LEU A 1 162 ? -7.562  -3.560  -13.725 1.000 8.784  0 177  LEU A CD2  1 ? 
ATOM   2637 H H    . LEU A 1 162 ? -7.432  -2.487  -18.050 1.000 7.312  0 177  LEU A H    1 c 
ATOM   2638 H HA   . LEU A 1 162 ? -6.436  -4.333  -16.173 1.000 7.284  0 177  LEU A HA   1 c 
ATOM   2639 H HB2  . LEU A 1 162 ? -9.236  -3.914  -16.574 1.000 7.581  0 177  LEU A HB2  1 c 
ATOM   2640 H HB3  . LEU A 1 162 ? -8.619  -5.022  -15.611 1.000 7.579  0 177  LEU A HB3  1 c 
ATOM   2641 H HG   . LEU A 1 162 ? -8.278  -2.223  -15.110 1.000 8.589  0 177  LEU A HG   1 c 
ATOM   2642 H HD11 . LEU A 1 162 ? -10.546 -2.700  -14.953 1.000 8.942  0 177  LEU A HD11 1 c 
ATOM   2643 H HD12 . LEU A 1 162 ? -9.974  -2.385  -13.507 1.000 8.942  0 177  LEU A HD12 1 c 
ATOM   2644 H HD13 . LEU A 1 162 ? -10.251 -3.886  -13.942 1.000 8.942  0 177  LEU A HD13 1 c 
ATOM   2645 H HD21 . LEU A 1 162 ? -6.656  -3.446  -14.058 1.000 8.839  0 177  LEU A HD21 1 c 
ATOM   2646 H HD22 . LEU A 1 162 ? -7.712  -4.495  -13.509 1.000 8.851  0 177  LEU A HD22 1 c 
ATOM   2647 H HD23 . LEU A 1 162 ? -7.680  -3.021  -12.924 1.000 8.858  0 177  LEU A HD23 1 c 
ATOM   2648 N N    . SER A 1 163 ? -6.597  -6.233  -17.726 1.000 7.300  0 178  SER A N    1 ? 
ATOM   2649 C CA   . SER A 1 163 ? -6.916  -7.444  -18.455 1.000 7.278  0 178  SER A CA   1 ? 
ATOM   2650 C C    . SER A 1 163 ? -7.676  -8.376  -17.520 1.000 6.932  0 178  SER A C    1 ? 
ATOM   2651 O O    . SER A 1 163 ? -8.098  -7.995  -16.436 1.000 8.521  0 178  SER A O    1 ? 
ATOM   2652 C CB   . SER A 1 163 ? -5.705  -8.090  -19.103 1.000 7.701  0 178  SER A CB   1 ? 
ATOM   2653 O OG   . SER A 1 163 ? -4.873  -8.684  -18.121 1.000 7.474  0 178  SER A OG   1 ? 
ATOM   2654 H H    . SER A 1 163 ? -5.875  -6.231  -17.167 1.000 7.313  0 178  SER A H    1 c 
ATOM   2655 H HA   . SER A 1 163 ? -7.538  -7.196  -19.184 1.000 7.293  0 178  SER A HA   1 c 
ATOM   2656 H HB2  . SER A 1 163 ? -5.997  -8.768  -19.740 1.000 7.545  0 178  SER A HB2  1 c 
ATOM   2657 H HB3  . SER A 1 163 ? -5.200  -7.412  -19.589 1.000 7.548  0 178  SER A HB3  1 c 
ATOM   2658 H HG   . SER A 1 163 ? -4.208  -9.035  -18.509 0.000 7.470  0 178  SER A HG   1 c 
ATOM   2659 N N    . GLU A 1 164 ? -7.776  -9.653  -17.908 1.000 7.263  0 179  GLU A N    1 ? 
ATOM   2660 C CA   . GLU A 1 164 ? -8.427  -10.646 -17.074 1.000 7.188  0 179  GLU A CA   1 ? 
ATOM   2661 C C    . GLU A 1 164 ? -7.498  -11.217 -16.013 1.000 7.879  0 179  GLU A C    1 ? 
ATOM   2662 O O    . GLU A 1 164 ? -7.980  -11.886 -15.089 1.000 8.919  0 179  GLU A O    1 ? 
ATOM   2663 C CB   . GLU A 1 164 ? -9.116  -11.718 -17.906 1.000 7.391  0 179  GLU A CB   1 ? 
ATOM   2664 C CG   . GLU A 1 164 ? -10.273 -11.159 -18.697 1.000 7.390  0 179  GLU A CG   1 ? 
ATOM   2665 C CD   . GLU A 1 164 ? -11.062 -12.208 -19.470 1.000 7.540  0 179  GLU A CD   1 ? 
ATOM   2666 O OE1  . GLU A 1 164 ? -10.471 -13.058 -20.168 1.000 8.409  0 179  GLU A OE1  1 ? 
ATOM   2667 O OE2  . GLU A 1 164 ? -12.330 -12.149 -19.387 1.000 8.421  0 179  GLU A OE2  1 ? 
ATOM   2668 H H    . GLU A 1 164 ? -7.446  -9.911  -18.720 1.000 7.175  0 179  GLU A H    1 c 
ATOM   2669 H HA   . GLU A 1 164 ? -9.158  -10.184 -16.590 1.000 7.369  0 179  GLU A HA   1 c 
ATOM   2670 H HB2  . GLU A 1 164 ? -8.463  -12.115 -18.519 1.000 7.352  0 179  GLU A HB2  1 c 
ATOM   2671 H HB3  . GLU A 1 164 ? -9.437  -12.425 -17.310 1.000 7.363  0 179  GLU A HB3  1 c 
ATOM   2672 H HG2  . GLU A 1 164 ? -10.885 -10.697 -18.085 1.000 7.430  0 179  GLU A HG2  1 c 
ATOM   2673 H HG3  . GLU A 1 164 ? -9.933  -10.494 -19.333 1.000 7.425  0 179  GLU A HG3  1 c 
ATOM   2674 N N    . ASP A 1 165 ? -6.197  -10.918 -16.080 1.000 7.311  0 180  ASP A N    1 ? 
ATOM   2675 C CA   . ASP A 1 165 ? -5.251  -11.368 -15.067 1.000 7.439  0 180  ASP A CA   1 ? 
ATOM   2676 C C    . ASP A 1 165 ? -4.165  -10.374 -14.714 1.000 7.821  0 180  ASP A C    1 ? 
ATOM   2677 O O    . ASP A 1 165 ? -3.197  -10.745 -14.046 1.000 8.974  0 180  ASP A O    1 ? 
ATOM   2678 C CB   . ASP A 1 165 ? -4.631  -12.721 -15.409 1.000 9.025  0 180  ASP A CB   1 ? 
ATOM   2679 C CG   . ASP A 1 165 ? -3.954  -13.454 -14.272 1.000 9.288  0 180  ASP A CG   1 ? 
ATOM   2680 O OD1  . ASP A 1 165 ? -4.573  -13.555 -13.219 1.000 11.879 0 180  ASP A OD1  1 ? 
ATOM   2681 O OD2  . ASP A 1 165 ? -2.778  -13.871 -14.486 1.000 10.261 0 180  ASP A OD2  1 ? 
ATOM   2682 H H    . ASP A 1 165 ? -5.881  -10.442 -16.793 1.000 7.461  0 180  ASP A H    1 c 
ATOM   2683 H HA   . ASP A 1 165 ? -5.764  -11.529 -14.244 1.000 7.835  0 180  ASP A HA   1 c 
ATOM   2684 H HB2  . ASP A 1 165 ? -5.342  -13.296 -15.753 1.000 8.681  0 180  ASP A HB2  1 c 
ATOM   2685 H HB3  . ASP A 1 165 ? -3.975  -12.593 -16.127 1.000 8.712  0 180  ASP A HB3  1 c 
ATOM   2686 N N    . HIS A 1 166 ? -4.298  -9.111  -15.118 1.000 7.044  0 181  HIS A N    1 ? 
ATOM   2687 C CA   . HIS A 1 166 ? -3.261  -8.132  -14.842 1.000 7.335  0 181  HIS A CA   1 ? 
ATOM   2688 C C    . HIS A 1 166 ? -3.800  -6.706  -14.892 1.000 7.353  0 181  HIS A C    1 ? 
ATOM   2689 O O    . HIS A 1 166 ? -4.898  -6.482  -15.392 1.000 7.620  0 181  HIS A O    1 ? 
ATOM   2690 C CB   . HIS A 1 166 ? -2.108  -8.305  -15.824 1.000 7.928  0 181  HIS A CB   1 ? 
ATOM   2691 C CG   . HIS A 1 166 ? -0.880  -7.550  -15.553 1.000 7.871  0 181  HIS A CG   1 ? 
ATOM   2692 N ND1  . HIS A 1 166 ? -0.343  -7.423  -14.313 1.000 9.180  0 181  HIS A ND1  1 ? 
ATOM   2693 C CD2  . HIS A 1 166 ? -0.039  -6.933  -16.399 1.000 8.383  0 181  HIS A CD2  1 ? 
ATOM   2694 C CE1  . HIS A 1 166 ? 0.774   -6.699  -14.411 1.000 9.681  0 181  HIS A CE1  1 ? 
ATOM   2695 N NE2  . HIS A 1 166 ? 1.016   -6.433  -15.661 1.000 8.885  0 181  HIS A NE2  1 ? 
ATOM   2696 H H    . HIS A 1 166 ? -5.051  -8.847  -15.564 1.000 7.291  0 181  HIS A H    1 c 
ATOM   2697 H HA   . HIS A 1 166 ? -2.923  -8.297  -13.930 1.000 7.451  0 181  HIS A HA   1 c 
ATOM   2698 H HB2  . HIS A 1 166 ? -1.880  -9.259  -15.863 1.000 7.812  0 181  HIS A HB2  1 c 
ATOM   2699 H HB3  . HIS A 1 166 ? -2.430  -8.063  -16.719 1.000 7.783  0 181  HIS A HB3  1 c 
ATOM   2700 H HD1  . HIS A 1 166 ? -0.674  -7.775  -13.576 0.000 9.180  0 181  HIS A HD1  1 c 
ATOM   2701 H HD2  . HIS A 1 166 ? -0.127  -6.878  -17.330 1.000 8.380  0 181  HIS A HD2  1 c 
ATOM   2702 H HE1  . HIS A 1 166 ? 1.330   -6.472  -13.686 1.000 9.353  0 181  HIS A HE1  1 c 
ATOM   2703 H HE2  . HIS A 1 166 ? 1.698   -5.970  -15.960 0.000 8.890  0 181  HIS A HE2  1 c 
ATOM   2704 N N    . ALA A 1 167 ? -3.014  -5.747  -14.372 1.000 6.789  0 182  ALA A N    1 ? 
ATOM   2705 C CA   . ALA A 1 167 ? -3.387  -4.340  -14.292 1.000 6.955  0 182  ALA A CA   1 ? 
ATOM   2706 C C    . ALA A 1 167 ? -2.136  -3.529  -14.579 1.000 7.950  0 182  ALA A C    1 ? 
ATOM   2707 O O    . ALA A 1 167 ? -1.042  -3.873  -14.164 1.000 7.932  0 182  ALA A O    1 ? 
ATOM   2708 C CB   . ALA A 1 167 ? -3.938  -4.008  -12.925 1.000 7.311  0 182  ALA A CB   1 ? 
ATOM   2709 H H    . ALA A 1 167 ? -2.208  -5.994  -14.020 1.000 6.986  0 182  ALA A H    1 c 
ATOM   2710 H HA   . ALA A 1 167 ? -4.069  -4.147  -14.990 1.000 7.172  0 182  ALA A HA   1 c 
ATOM   2711 H HB1  . ALA A 1 167 ? -4.726  -4.550  -12.749 1.000 7.203  0 182  ALA A HB1  1 c 
ATOM   2712 H HB2  . ALA A 1 167 ? -3.265  -4.190  -12.248 1.000 7.203  0 182  ALA A HB2  1 c 
ATOM   2713 H HB3  . ALA A 1 167 ? -4.182  -3.068  -12.890 1.000 7.203  0 182  ALA A HB3  1 c 
ATOM   2714 N N    . TRP A 1 168 ? -2.357  -2.392  -15.227 1.000 7.384  0 183  TRP A N    1 ? 
ATOM   2715 C CA   . TRP A 1 168 ? -1.300  -1.428  -15.529 1.000 7.400  0 183  TRP A CA   1 ? 
ATOM   2716 C C    . TRP A 1 168 ? -1.945  -0.060  -15.644 1.000 7.523  0 183  TRP A C    1 ? 
ATOM   2717 O O    . TRP A 1 168 ? -3.071  0.113   -15.212 1.000 7.787  0 183  TRP A O    1 ? 
ATOM   2718 C CB   . TRP A 1 168 ? -0.481  -1.858  -16.742 1.000 7.239  0 183  TRP A CB   1 ? 
ATOM   2719 C CG   . TRP A 1 168 ? -1.211  -1.987  -18.036 1.000 7.606  0 183  TRP A CG   1 ? 
ATOM   2720 C CD1  . TRP A 1 168 ? -1.280  -1.085  -19.037 1.000 8.128  0 183  TRP A CD1  1 ? 
ATOM   2721 C CD2  . TRP A 1 168 ? -1.930  -3.142  -18.506 1.000 7.705  0 183  TRP A CD2  1 ? 
ATOM   2722 N NE1  . TRP A 1 168 ? -2.013  -1.562  -20.093 1.000 8.246  0 183  TRP A NE1  1 ? 
ATOM   2723 C CE2  . TRP A 1 168 ? -2.400  -2.840  -19.799 1.000 7.653  0 183  TRP A CE2  1 ? 
ATOM   2724 C CE3  . TRP A 1 168 ? -2.184  -4.404  -17.982 1.000 8.202  0 183  TRP A CE3  1 ? 
ATOM   2725 C CZ2  . TRP A 1 168 ? -3.138  -3.720  -20.562 1.000 7.930  0 183  TRP A CZ2  1 ? 
ATOM   2726 C CZ3  . TRP A 1 168 ? -2.945  -5.280  -18.737 1.000 8.622  0 183  TRP A CZ3  1 ? 
ATOM   2727 C CH2  . TRP A 1 168 ? -3.406  -4.936  -20.007 1.000 8.727  0 183  TRP A CH2  1 ? 
ATOM   2728 H H    . TRP A 1 168 ? -3.208  -2.200  -15.499 1.000 7.512  0 183  TRP A H    1 c 
ATOM   2729 H HA   . TRP A 1 168 ? -0.683  -1.403  -14.749 1.000 7.395  0 183  TRP A HA   1 c 
ATOM   2730 H HB2  . TRP A 1 168 ? 0.254   -1.221  -16.860 1.000 7.371  0 183  TRP A HB2  1 c 
ATOM   2731 H HB3  . TRP A 1 168 ? -0.064  -2.721  -16.535 1.000 7.362  0 183  TRP A HB3  1 c 
ATOM   2732 H HD1  . TRP A 1 168 ? -0.905  -0.221  -19.002 1.000 8.024  0 183  TRP A HD1  1 c 
ATOM   2733 H HE1  . TRP A 1 168 ? -2.183  -1.131  -20.834 1.000 8.069  0 183  TRP A HE1  1 c 
ATOM   2734 H HE3  . TRP A 1 168 ? -1.889  -4.637  -17.119 1.000 8.177  0 183  TRP A HE3  1 c 
ATOM   2735 H HZ2  . TRP A 1 168 ? -3.451  -3.485  -21.414 1.000 8.068  0 183  TRP A HZ2  1 c 
ATOM   2736 H HZ3  . TRP A 1 168 ? -3.134  -6.138  -18.395 1.000 8.530  0 183  TRP A HZ3  1 c 
ATOM   2737 H HH2  . TRP A 1 168 ? -3.899  -5.567  -20.502 1.000 8.494  0 183  TRP A HH2  1 c 
ATOM   2738 N N    . VAL A 1 169 ? -1.249  0.938   -16.240 1.000 7.737  0 184  VAL A N    1 ? 
ATOM   2739 C CA   . VAL A 1 169 ? -1.876  2.230   -16.458 1.000 8.651  0 184  VAL A CA   1 ? 
ATOM   2740 C C    . VAL A 1 169 ? -1.775  2.671   -17.919 1.000 7.386  0 184  VAL A C    1 ? 
ATOM   2741 O O    . VAL A 1 169 ? -0.840  2.284   -18.656 1.000 8.201  0 184  VAL A O    1 ? 
ATOM   2742 C CB   . VAL A 1 169 ? -1.336  3.342   -15.539 1.000 9.940  0 184  VAL A CB   1 ? 
ATOM   2743 C CG1  . VAL A 1 169 ? -1.483  2.986   -14.069 1.000 10.962 0 184  VAL A CG1  1 ? 
ATOM   2744 C CG2  . VAL A 1 169 ? 0.079   3.703   -15.819 1.000 11.744 0 184  VAL A CG2  1 ? 
ATOM   2745 H H    . VAL A 1 169 ? -0.382  0.812   -16.497 1.000 7.872  0 184  VAL A H    1 c 
ATOM   2746 H HA   . VAL A 1 169 ? -2.823  2.126   -16.255 1.000 8.425  0 184  VAL A HA   1 c 
ATOM   2747 H HB   . VAL A 1 169 ? -1.884  4.144   -15.705 1.000 10.188 0 184  VAL A HB   1 c 
ATOM   2748 H HG11 . VAL A 1 169 ? -0.940  2.206   -13.867 1.000 10.636 0 184  VAL A HG11 1 c 
ATOM   2749 H HG12 . VAL A 1 169 ? -2.415  2.790   -13.875 1.000 10.647 0 184  VAL A HG12 1 c 
ATOM   2750 H HG13 . VAL A 1 169 ? -1.189  3.734   -13.523 1.000 10.650 0 184  VAL A HG13 1 c 
ATOM   2751 H HG21 . VAL A 1 169 ? 0.392   4.334   -15.149 1.000 11.147 0 184  VAL A HG21 1 c 
ATOM   2752 H HG22 . VAL A 1 169 ? 0.145   4.110   -16.699 1.000 11.137 0 184  VAL A HG22 1 c 
ATOM   2753 H HG23 . VAL A 1 169 ? 0.630   2.903   -15.790 1.000 11.144 0 184  VAL A HG23 1 c 
ATOM   2754 N N    . VAL A 1 170 ? -2.726  3.527   -18.285 1.000 8.486  0 185  VAL A N    1 ? 
ATOM   2755 C CA   . VAL A 1 170 ? -2.662  4.315   -19.507 1.000 8.961  0 185  VAL A CA   1 ? 
ATOM   2756 C C    . VAL A 1 170 ? -2.519  5.782   -19.128 1.000 9.392  0 185  VAL A C    1 ? 
ATOM   2757 O O    . VAL A 1 170 ? -2.896  6.198   -18.027 1.000 9.936  0 185  VAL A O    1 ? 
ATOM   2758 C CB   . VAL A 1 170 ? -3.860  4.104   -20.454 1.000 10.308 0 185  VAL A CB   1 ? 
ATOM   2759 C CG1  . VAL A 1 170 ? -3.893  2.671   -20.958 1.000 10.431 0 185  VAL A CG1  1 ? 
ATOM   2760 C CG2  . VAL A 1 170 ? -5.164  4.485   -19.775 1.000 12.446 0 185  VAL A CG2  1 ? 
ATOM   2761 H H    . VAL A 1 170 ? -3.452  3.634   -17.739 1.000 8.358  0 185  VAL A H    1 c 
ATOM   2762 H HA   . VAL A 1 170 ? -1.856  4.052   -19.986 1.000 9.155  0 185  VAL A HA   1 c 
ATOM   2763 H HB   . VAL A 1 170 ? -3.731  4.700   -21.229 1.000 10.428 0 185  VAL A HB   1 c 
ATOM   2764 H HG11 . VAL A 1 170 ? -3.925  2.061   -20.203 1.000 10.366 0 185  VAL A HG11 1 c 
ATOM   2765 H HG12 . VAL A 1 170 ? -3.096  2.494   -21.483 1.000 10.398 0 185  VAL A HG12 1 c 
ATOM   2766 H HG13 . VAL A 1 170 ? -4.681  2.539   -21.513 1.000 10.390 0 185  VAL A HG13 1 c 
ATOM   2767 H HG21 . VAL A 1 170 ? -5.904  4.338   -20.388 1.000 11.754 0 185  VAL A HG21 1 c 
ATOM   2768 H HG22 . VAL A 1 170 ? -5.140  5.422   -19.521 1.000 11.744 0 185  VAL A HG22 1 c 
ATOM   2769 H HG23 . VAL A 1 170 ? -5.291  3.938   -18.982 1.000 11.715 0 185  VAL A HG23 1 c 
ATOM   2770 N N    . PHE A 1 171 ? -1.925  6.582   -20.031 1.000 8.746  0 186  PHE A N    1 ? 
ATOM   2771 C CA   . PHE A 1 171 ? -1.640  7.987   -19.720 1.000 8.901  0 186  PHE A CA   1 ? 
ATOM   2772 C C    . PHE A 1 171 ? -1.178  8.695   -20.981 1.000 10.569 0 186  PHE A C    1 ? 
ATOM   2773 O O    . PHE A 1 171 ? -1.000  8.089   -22.038 1.000 9.891  0 186  PHE A O    1 ? 
ATOM   2774 C CB   . PHE A 1 171 ? -0.534  8.110   -18.663 1.000 9.291  0 186  PHE A CB   1 ? 
ATOM   2775 C CG   . PHE A 1 171 ? 0.860   7.719   -19.132 1.000 9.230  0 186  PHE A CG   1 ? 
ATOM   2776 C CD1  . PHE A 1 171 ? 1.255   6.407   -19.246 1.000 9.896  0 186  PHE A CD1  1 ? 
ATOM   2777 C CD2  . PHE A 1 171 ? 1.755   8.692   -19.580 1.000 9.927  0 186  PHE A CD2  1 ? 
ATOM   2778 C CE1  . PHE A 1 171 ? 2.494   6.041   -19.719 1.000 10.620 0 186  PHE A CE1  1 ? 
ATOM   2779 C CE2  . PHE A 1 171 ? 3.016   8.351   -20.057 1.000 9.808  0 186  PHE A CE2  1 ? 
ATOM   2780 C CZ   . PHE A 1 171 ? 3.362   7.023   -20.168 1.000 9.774  0 186  PHE A CZ   1 ? 
ATOM   2781 H H    . PHE A 1 171 ? -1.693  6.249   -20.851 1.000 8.944  0 186  PHE A H    1 c 
ATOM   2782 H HA   . PHE A 1 171 ? -2.466  8.421   -19.384 1.000 9.242  0 186  PHE A HA   1 c 
ATOM   2783 H HB2  . PHE A 1 171 ? -0.509  9.042   -18.350 1.000 9.205  0 186  PHE A HB2  1 c 
ATOM   2784 H HB3  . PHE A 1 171 ? -0.774  7.550   -17.892 1.000 9.196  0 186  PHE A HB3  1 c 
ATOM   2785 H HD1  . PHE A 1 171 ? 0.655   5.731   -18.974 1.000 9.896  0 186  PHE A HD1  1 c 
ATOM   2786 H HD2  . PHE A 1 171 ? 1.507   9.602   -19.535 1.000 9.753  0 186  PHE A HD2  1 c 
ATOM   2787 H HE1  . PHE A 1 171 ? 2.733   5.130   -19.774 1.000 10.227 0 186  PHE A HE1  1 c 
ATOM   2788 H HE2  . PHE A 1 171 ? 3.611   9.023   -20.346 1.000 9.829  0 186  PHE A HE2  1 c 
ATOM   2789 H HZ   . PHE A 1 171 ? 4.226   6.786   -20.466 1.000 9.968  0 186  PHE A HZ   1 c 
ATOM   2790 N N    . GLY A 1 172 ? -0.932  9.996   -20.853 1.000 10.682 0 187  GLY A N    1 ? 
ATOM   2791 C CA   . GLY A 1 172 ? -0.208  10.721  -21.885 1.000 11.270 0 187  GLY A CA   1 ? 
ATOM   2792 C C    . GLY A 1 172 ? -1.156  11.316  -22.910 1.000 11.466 0 187  GLY A C    1 ? 
ATOM   2793 O O    . GLY A 1 172 ? -2.367  11.332  -22.769 1.000 13.511 0 187  GLY A O    1 ? 
ATOM   2794 H H    . GLY A 1 172 ? -1.224  10.447  -20.113 1.000 10.753 0 187  GLY A H    1 c 
ATOM   2795 H HA2  . GLY A 1 172 ? 0.316   11.442  -21.463 1.000 11.169 0 187  GLY A HA2  1 c 
ATOM   2796 H HA3  . GLY A 1 172 ? 0.423   10.108  -22.331 1.000 11.165 0 187  GLY A HA3  1 c 
ATOM   2797 N N    . PRO A 1 173 ? -0.573  11.767  -24.060 1.000 12.580 0 188  PRO A N    1 ? 
ATOM   2798 C CA   . PRO A 1 173 ? -1.335  12.341  -25.156 1.000 13.299 0 188  PRO A CA   1 ? 
ATOM   2799 C C    . PRO A 1 173 ? -2.426  11.392  -25.619 1.000 14.006 0 188  PRO A C    1 ? 
ATOM   2800 O O    . PRO A 1 173 ? -2.166  10.231  -25.940 1.000 13.191 0 188  PRO A O    1 ? 
ATOM   2801 C CB   . PRO A 1 173 ? -0.249  12.591  -26.240 1.000 13.348 0 188  PRO A CB   1 ? 
ATOM   2802 C CG   . PRO A 1 173 ? 1.015   12.740  -25.501 1.000 13.466 0 188  PRO A CG   1 ? 
ATOM   2803 C CD   . PRO A 1 173 ? 0.881   11.776  -24.331 1.000 12.407 0 188  PRO A CD   1 ? 
ATOM   2804 H HA   . PRO A 1 173 ? -1.727  13.204  -24.869 1.000 13.318 0 188  PRO A HA   1 c 
ATOM   2805 H HB2  . PRO A 1 173 ? -0.199  11.831  -26.866 1.000 13.368 0 188  PRO A HB2  1 c 
ATOM   2806 H HB3  . PRO A 1 173 ? -0.451  13.408  -26.754 1.000 13.365 0 188  PRO A HB3  1 c 
ATOM   2807 H HG2  . PRO A 1 173 ? 1.781   12.501  -26.065 1.000 13.195 0 188  PRO A HG2  1 c 
ATOM   2808 H HG3  . PRO A 1 173 ? 1.129   13.661  -25.184 1.000 13.195 0 188  PRO A HG3  1 c 
ATOM   2809 H HD2  . PRO A 1 173 ? 1.202   10.880  -24.575 1.000 12.675 0 188  PRO A HD2  1 c 
ATOM   2810 H HD3  . PRO A 1 173 ? 1.387   12.099  -23.552 1.000 12.669 0 188  PRO A HD3  1 c 
ATOM   2811 N N    . ASN A 1 174 ? -3.685  11.842  -25.559 1.000 15.677 0 189  ASN A N    1 ? 
ATOM   2812 C CA   . ASN A 1 174 ? -4.839  11.052  -25.961 1.000 17.533 0 189  ASN A CA   1 ? 
ATOM   2813 C C    . ASN A 1 174 ? -5.023  9.790   -25.121 1.000 16.233 0 189  ASN A C    1 ? 
ATOM   2814 O O    . ASN A 1 174 ? -5.741  8.863   -25.537 1.000 18.566 0 189  ASN A O    1 ? 
ATOM   2815 C CB   . ASN A 1 174 ? -4.783  10.589  -27.414 1.000 21.342 0 189  ASN A CB   1 ? 
ATOM   2816 C CG   . ASN A 1 174 ? -4.567  11.715  -28.389 1.000 23.656 0 189  ASN A CG   1 ? 
ATOM   2817 O OD1  . ASN A 1 174 ? -5.281  12.723  -28.323 1.000 27.680 0 189  ASN A OD1  1 ? 
ATOM   2818 N ND2  . ASN A 1 174 ? -3.580  11.562  -29.269 1.000 26.775 0 189  ASN A ND2  1 ? 
ATOM   2819 H H    . ASN A 1 174 ? -3.831  12.690  -25.249 1.000 15.614 0 189  ASN A H    1 c 
ATOM   2820 H HA   . ASN A 1 174 ? -5.642  11.612  -25.860 1.000 17.546 0 189  ASN A HA   1 c 
ATOM   2821 H HB2  . ASN A 1 174 ? -4.063  9.936   -27.514 1.000 20.833 0 189  ASN A HB2  1 c 
ATOM   2822 H HB3  . ASN A 1 174 ? -5.624  10.142  -27.637 1.000 20.847 0 189  ASN A HB3  1 c 
ATOM   2823 H HD21 . ASN A 1 174 ? -3.133  10.797  -29.316 1.000 25.688 0 189  ASN A HD21 1 c 
ATOM   2824 H HD22 . ASN A 1 174 ? -3.369  12.231  -29.812 1.000 25.753 0 189  ASN A HD22 1 c 
ATOM   2825 N N    . GLY A 1 175 ? -4.344  9.702   -23.977 1.000 14.964 0 190  GLY A N    1 ? 
ATOM   2826 C CA   . GLY A 1 175 ? -4.363  8.499   -23.164 1.000 16.297 0 190  GLY A CA   1 ? 
ATOM   2827 C C    . GLY A 1 175 ? -3.795  7.278   -23.887 1.000 13.621 0 190  GLY A C    1 ? 
ATOM   2828 O O    . GLY A 1 175 ? -4.149  6.140   -23.594 1.000 14.987 0 190  GLY A O    1 ? 
ATOM   2829 H H    . GLY A 1 175 ? -3.871  10.424  -23.676 1.000 15.557 0 190  GLY A H    1 c 
ATOM   2830 H HA2  . GLY A 1 175 ? -3.840  8.662   -22.344 1.000 15.342 0 190  GLY A HA2  1 c 
ATOM   2831 H HA3  . GLY A 1 175 ? -5.293  8.313   -22.894 1.000 15.342 0 190  GLY A HA3  1 c 
ATOM   2832 N N    . GLU A 1 176 ? -2.894  7.505   -24.849 1.000 11.620 0 191  GLU A N    1 ? 
ATOM   2833 C CA   . GLU A 1 176 ? -2.470  6.440   -25.735 1.000 11.253 0 191  GLU A CA   1 ? 
ATOM   2834 C C    . GLU A 1 176 ? -1.248  5.675   -25.258 1.000 9.765  0 191  GLU A C    1 ? 
ATOM   2835 O O    . GLU A 1 176 ? -0.956  4.610   -25.800 1.000 11.676 0 191  GLU A O    1 ? 
ATOM   2836 C CB   . GLU A 1 176 ? -2.194  6.987   -27.132 1.000 12.845 0 191  GLU A CB   1 ? 
ATOM   2837 C CG   . GLU A 1 176 ? -0.936  7.841   -27.280 1.000 15.838 0 191  GLU A CG   1 ? 
ATOM   2838 C CD   . GLU A 1 176 ? -0.941  8.800   -28.476 1.000 19.050 0 191  GLU A CD   1 ? 
ATOM   2839 O OE1  . GLU A 1 176 ? -1.931  8.772   -29.249 1.000 21.919 0 191  GLU A OE1  1 ? 
ATOM   2840 O OE2  . GLU A 1 176 ? 0.061   9.573   -28.648 1.000 18.790 0 191  GLU A OE2  1 ? 
ATOM   2841 H H    . GLU A 1 176 ? -2.529  8.336   -24.947 1.000 12.092 0 191  GLU A H    1 c 
ATOM   2842 H HA   . GLU A 1 176 ? -3.218  5.796   -25.817 1.000 11.361 0 191  GLU A HA   1 c 
ATOM   2843 H HB2  . GLU A 1 176 ? -2.129  6.232   -27.752 1.000 13.087 0 191  GLU A HB2  1 c 
ATOM   2844 H HB3  . GLU A 1 176 ? -2.965  7.527   -27.406 1.000 13.143 0 191  GLU A HB3  1 c 
ATOM   2845 H HG2  . GLU A 1 176 ? -0.805  8.363   -26.462 1.000 15.695 0 191  GLU A HG2  1 c 
ATOM   2846 H HG3  . GLU A 1 176 ? -0.161  7.246   -27.370 1.000 15.705 0 191  GLU A HG3  1 c 
ATOM   2847 N N    . GLN A 1 177 ? -0.524  6.145   -24.258 1.000 8.442  0 192  GLN A N    1 ? 
ATOM   2848 C CA   . GLN A 1 177 ? 0.615   5.470   -23.702 1.000 8.164  0 192  GLN A CA   1 ? 
ATOM   2849 C C    . GLN A 1 177 ? 0.177   4.382   -22.719 1.000 7.947  0 192  GLN A C    1 ? 
ATOM   2850 O O    . GLN A 1 177 ? -0.778  4.596   -21.975 1.000 8.666  0 192  GLN A O    1 ? 
ATOM   2851 C CB   . GLN A 1 177 ? 1.620   6.421   -23.038 1.000 8.825  0 192  GLN A CB   1 ? 
ATOM   2852 C CG   . GLN A 1 177 ? 2.297   7.372   -24.028 1.000 9.366  0 192  GLN A CG   1 ? 
ATOM   2853 C CD   . GLN A 1 177 ? 3.006   6.624   -25.137 1.000 9.424  0 192  GLN A CD   1 ? 
ATOM   2854 O OE1  . GLN A 1 177 ? 3.724   5.659   -24.895 1.000 9.866  0 192  GLN A OE1  1 ? 
ATOM   2855 N NE2  . GLN A 1 177 ? 2.719   7.002   -26.375 1.000 10.620 0 192  GLN A NE2  1 ? 
ATOM   2856 H H    . GLN A 1 177 ? -0.758  6.952   -23.899 1.000 8.707  0 192  GLN A H    1 c 
ATOM   2857 H HA   . GLN A 1 177 ? 1.089   5.022   -24.447 1.000 8.323  0 192  GLN A HA   1 c 
ATOM   2858 H HB2  . GLN A 1 177 ? 1.158   6.947   -22.354 1.000 8.798  0 192  GLN A HB2  1 c 
ATOM   2859 H HB3  . GLN A 1 177 ? 2.309   5.888   -22.589 1.000 8.802  0 192  GLN A HB3  1 c 
ATOM   2860 H HG2  . GLN A 1 177 ? 1.623   7.969   -24.417 1.000 9.269  0 192  GLN A HG2  1 c 
ATOM   2861 H HG3  . GLN A 1 177 ? 2.948   7.926   -23.549 1.000 9.257  0 192  GLN A HG3  1 c 
ATOM   2862 H HE21 . GLN A 1 177 ? 2.198   7.705   -26.522 1.000 10.220 0 192  GLN A HE21 1 c 
ATOM   2863 H HE22 . GLN A 1 177 ? 3.052   6.548   -27.062 1.000 10.230 0 192  GLN A HE22 1 c 
ATOM   2864 N N    . THR A 1 178 ? 0.971   3.321   -22.604 1.000 8.389  0 193  THR A N    1 ? 
ATOM   2865 C CA   . THR A 1 178 ? 0.812   2.303   -21.566 1.000 8.012  0 193  THR A CA   1 ? 
ATOM   2866 C C    . THR A 1 178 ? 2.082   2.247   -20.738 1.000 7.805  0 193  THR A C    1 ? 
ATOM   2867 O O    . THR A 1 178 ? 3.207   2.383   -21.236 1.000 8.843  0 193  THR A O    1 ? 
ATOM   2868 C CB   . THR A 1 178 ? 0.488   0.915   -22.151 1.000 10.134 0 193  THR A CB   1 ? 
ATOM   2869 O OG1  . THR A 1 178 ? 1.538   0.443   -22.975 1.000 9.959  0 193  THR A OG1  1 ? 
ATOM   2870 C CG2  . THR A 1 178 ? -0.813  0.951   -22.947 1.000 12.660 0 193  THR A CG2  1 ? 
ATOM   2871 H H    . THR A 1 178 ? 1.653   3.221   -23.204 1.000 8.197  0 193  THR A H    1 c 
ATOM   2872 H HA   . THR A 1 178 ? 0.071   2.571   -20.984 1.000 8.393  0 193  THR A HA   1 c 
ATOM   2873 H HB   . THR A 1 178 ? 0.366   0.282   -21.403 1.000 10.086 0 193  THR A HB   1 c 
ATOM   2874 H HG1  . THR A 1 178 ? 1.663   0.994   -23.629 0.000 9.970  0 193  THR A HG1  1 c 
ATOM   2875 H HG21 . THR A 1 178 ? -0.986  0.074   -23.327 1.000 11.847 0 193  THR A HG21 1 c 
ATOM   2876 H HG22 . THR A 1 178 ? -0.739  1.604   -23.664 1.000 11.830 0 193  THR A HG22 1 c 
ATOM   2877 H HG23 . THR A 1 178 ? -1.546  1.198   -22.360 1.000 11.838 0 193  THR A HG23 1 c 
ATOM   2878 N N    . ALA A 1 179 ? 1.947   1.964   -19.441 1.000 7.805  0 194  ALA A N    1 ? 
ATOM   2879 C CA   . ALA A 1 179 ? 3.068   1.691   -18.573 1.000 8.350  0 194  ALA A CA   1 ? 
ATOM   2880 C C    . ALA A 1 179 ? 2.718   0.591   -17.573 1.000 9.060  0 194  ALA A C    1 ? 
ATOM   2881 O O    . ALA A 1 179 ? 1.711   0.716   -16.861 1.000 8.447  0 194  ALA A O    1 ? 
ATOM   2882 C CB   . ALA A 1 179 ? 3.544   2.924   -17.818 1.000 10.042 0 194  ALA A CB   1 ? 
ATOM   2883 H H    . ALA A 1 179 ? 1.107   1.943   -19.081 1.000 7.937  0 194  ALA A H    1 c 
ATOM   2884 H HA   . ALA A 1 179 ? 3.816   1.362   -19.139 1.000 8.666  0 194  ALA A HA   1 c 
ATOM   2885 H HB1  . ALA A 1 179 ? 3.867   3.589   -18.448 1.000 9.508  0 194  ALA A HB1  1 c 
ATOM   2886 H HB2  . ALA A 1 179 ? 2.808   3.297   -17.305 1.000 9.509  0 194  ALA A HB2  1 c 
ATOM   2887 H HB3  . ALA A 1 179 ? 4.265   2.679   -17.213 1.000 9.507  0 194  ALA A HB3  1 c 
ATOM   2888 N N    . GLU A 1 180 ? 3.631   -0.342  -17.434 1.000 8.971  0 195  GLU A N    1 ? 
ATOM   2889 C CA   . GLU A 1 180 ? 3.594   -1.284  -16.326 1.000 8.628  0 195  GLU A CA   1 ? 
ATOM   2890 C C    . GLU A 1 180 ? 3.917   -0.523  -15.058 1.000 10.139 0 195  GLU A C    1 ? 
ATOM   2891 O O    . GLU A 1 180 ? 4.856   0.273   -15.024 1.000 10.463 0 195  GLU A O    1 ? 
ATOM   2892 C CB   . GLU A 1 180 ? 4.620   -2.373  -16.567 1.000 9.378  0 195  GLU A CB   1 ? 
ATOM   2893 C CG   . GLU A 1 180 ? 4.335   -3.283  -17.758 1.000 9.890  0 195  GLU A CG   1 ? 
ATOM   2894 C CD   . GLU A 1 180 ? 3.353   -4.428  -17.552 1.000 10.085 0 195  GLU A CD   1 ? 
ATOM   2895 O OE1  . GLU A 1 180 ? 2.743   -4.469  -16.446 1.000 11.653 0 195  GLU A OE1  1 ? 
ATOM   2896 O OE2  . GLU A 1 180 ? 3.159   -5.233  -18.486 1.000 10.138 0 195  GLU A OE2  1 ? 
ATOM   2897 H H    . GLU A 1 180 ? 4.307   -0.407  -18.046 1.000 8.925  0 195  GLU A H    1 c 
ATOM   2898 H HA   . GLU A 1 180 ? 2.684   -1.672  -16.263 1.000 9.099  0 195  GLU A HA   1 c 
ATOM   2899 H HB2  . GLU A 1 180 ? 5.490   -1.949  -16.709 1.000 9.373  0 195  GLU A HB2  1 c 
ATOM   2900 H HB3  . GLU A 1 180 ? 4.688   -2.924  -15.759 1.000 9.339  0 195  GLU A HB3  1 c 
ATOM   2901 H HG2  . GLU A 1 180 ? 4.001   -2.730  -18.496 1.000 9.805  0 195  GLU A HG2  1 c 
ATOM   2902 H HG3  . GLU A 1 180 ? 5.185   -3.668  -18.061 1.000 9.813  0 195  GLU A HG3  1 c 
ATOM   2903 N N    . VAL A 1 181 ? 3.207   -0.848  -13.979 1.000 10.105 0 196  VAL A N    1 ? 
ATOM   2904 C CA   . VAL A 1 181 ? 3.385   -0.185  -12.682 1.000 10.092 0 196  VAL A CA   1 ? 
ATOM   2905 C C    . VAL A 1 181 ? 3.418   -1.212  -11.557 1.000 10.666 0 196  VAL A C    1 ? 
ATOM   2906 O O    . VAL A 1 181 ? 3.678   -0.774  -10.405 1.000 11.563 0 196  VAL A O    1 ? 
ATOM   2907 C CB   . VAL A 1 181 ? 2.330   0.901   -12.414 1.000 11.311 0 196  VAL A CB   1 ? 
ATOM   2908 C CG1  . VAL A 1 181 ? 2.393   2.045   -13.424 1.000 11.480 0 196  VAL A CG1  1 ? 
ATOM   2909 C CG2  . VAL A 1 181 ? 0.914   0.325   -12.273 1.000 11.319 0 196  VAL A CG2  1 ? 
ATOM   2910 H H    . VAL A 1 181 ? 2.561   -1.489  -14.056 1.000 10.090 0 196  VAL A H    1 c 
ATOM   2911 H HA   . VAL A 1 181 ? 4.257   0.255   -12.696 1.000 10.415 0 196  VAL A HA   1 c 
ATOM   2912 H HB   . VAL A 1 181 ? 2.555   1.296   -11.540 1.000 11.108 0 196  VAL A HB   1 c 
ATOM   2913 H HG11 . VAL A 1 181 ? 2.069   1.734   -14.287 1.000 11.435 0 196  VAL A HG11 1 c 
ATOM   2914 H HG12 . VAL A 1 181 ? 3.311   2.349   -13.516 1.000 11.457 0 196  VAL A HG12 1 c 
ATOM   2915 H HG13 . VAL A 1 181 ? 1.837   2.781   -13.116 1.000 11.436 0 196  VAL A HG13 1 c 
ATOM   2916 H HG21 . VAL A 1 181 ? 0.278   1.052   -12.162 1.000 11.305 0 196  VAL A HG21 1 c 
ATOM   2917 H HG22 . VAL A 1 181 ? 0.875   -0.258  -11.497 1.000 11.286 0 196  VAL A HG22 1 c 
ATOM   2918 H HG23 . VAL A 1 181 ? 0.689   -0.182  -13.070 1.000 11.308 0 196  VAL A HG23 1 c 
ATOM   2919 N N    . THR A 1 182 ? 3.147   -2.493  -11.780 1.000 9.926  0 197  THR A N    1 ? 
ATOM   2920 C CA   . THR A 1 182 ? 3.167   -3.512  -10.741 1.000 10.115 0 197  THR A CA   1 ? 
ATOM   2921 C C    . THR A 1 182 ? 3.755   -4.805  -11.295 1.000 9.889  0 197  THR A C    1 ? 
ATOM   2922 O O    . THR A 1 182 ? 4.176   -4.852  -12.471 1.000 11.414 0 197  THR A O    1 ? 
ATOM   2923 C CB   . THR A 1 182 ? 1.754   -3.697  -10.175 1.000 9.282  0 197  THR A CB   1 ? 
ATOM   2924 O OG1  . THR A 1 182 ? 1.897   -4.514  -8.999  1.000 9.185  0 197  THR A OG1  1 ? 
ATOM   2925 C CG2  . THR A 1 182 ? 0.783   -4.349  -11.139 1.000 9.124  0 197  THR A CG2  1 ? 
ATOM   2926 H H    . THR A 1 182 ? 2.938   -2.756  -12.629 1.000 10.138 0 197  THR A H    1 c 
ATOM   2927 H HA   . THR A 1 182 ? 3.749   -3.198  -10.015 1.000 9.893  0 197  THR A HA   1 c 
ATOM   2928 H HB   . THR A 1 182 ? 1.393   -2.816  -9.913  1.000 9.378  0 197  THR A HB   1 c 
ATOM   2929 H HG1  . THR A 1 182 ? 2.247   -5.274  -9.216  0.000 9.180  0 197  THR A HG1  1 c 
ATOM   2930 H HG21 . THR A 1 182 ? -0.117  -4.302  -10.775 1.000 9.172  0 197  THR A HG21 1 c 
ATOM   2931 H HG22 . THR A 1 182 ? 1.029   -5.279  -11.272 1.000 9.177  0 197  THR A HG22 1 c 
ATOM   2932 H HG23 . THR A 1 182 ? 0.810   -3.883  -11.991 1.000 9.175  0 197  THR A HG23 1 c 
ATOM   2933 N N    . TRP A 1 183 ? 3.862   -5.846  -10.477 1.000 8.746  0 198  TRP A N    1 ? 
ATOM   2934 C CA   . TRP A 1 183 ? 4.316   -7.157  -10.869 1.000 9.242  0 198  TRP A CA   1 ? 
ATOM   2935 C C    . TRP A 1 183 ? 3.160   -7.981  -11.421 1.000 10.267 0 198  TRP A C    1 ? 
ATOM   2936 O O    . TRP A 1 183 ? 2.012   -7.644  -11.168 1.000 9.682  0 198  TRP A O    1 ? 
ATOM   2937 C CB   . TRP A 1 183 ? 5.043   -7.862  -9.721  1.000 9.697  0 198  TRP A CB   1 ? 
ATOM   2938 C CG   . TRP A 1 183 ? 4.141   -8.263  -8.580  1.000 10.347 0 198  TRP A CG   1 ? 
ATOM   2939 C CD1  . TRP A 1 183 ? 3.570   -9.495  -8.421  1.000 13.630 0 198  TRP A CD1  1 ? 
ATOM   2940 C CD2  . TRP A 1 183 ? 3.806   -7.493  -7.419  1.000 11.334 0 198  TRP A CD2  1 ? 
ATOM   2941 N NE1  . TRP A 1 183 ? 2.797   -9.494  -7.284  1.000 14.403 0 198  TRP A NE1  1 ? 
ATOM   2942 C CE2  . TRP A 1 183 ? 2.942   -8.298  -6.651  1.000 13.089 0 198  TRP A CE2  1 ? 
ATOM   2943 C CE3  . TRP A 1 183 ? 4.121   -6.203  -7.000  1.000 11.715 0 198  TRP A CE3  1 ? 
ATOM   2944 C CZ2  . TRP A 1 183 ? 2.428   -7.829  -5.434  1.000 13.540 0 198  TRP A CZ2  1 ? 
ATOM   2945 C CZ3  . TRP A 1 183 ? 3.587   -5.744  -5.793  1.000 13.589 0 198  TRP A CZ3  1 ? 
ATOM   2946 C CH2  . TRP A 1 183 ? 2.757   -6.556  -5.058  1.000 13.130 0 198  TRP A CH2  1 ? 
ATOM   2947 H H    . TRP A 1 183 ? 3.626   -5.721  -9.604  1.000 9.179  0 198  TRP A H    1 c 
ATOM   2948 H HA   . TRP A 1 183 ? 4.976   -7.037  -11.604 1.000 9.425  0 198  TRP A HA   1 c 
ATOM   2949 H HB2  . TRP A 1 183 ? 5.481   -8.665  -10.076 1.000 9.736  0 198  TRP A HB2  1 c 
ATOM   2950 H HB3  . TRP A 1 183 ? 5.741   -7.263  -9.379  1.000 9.736  0 198  TRP A HB3  1 c 
ATOM   2951 H HD1  . TRP A 1 183 ? 3.595   -10.197 -9.050  1.000 12.985 0 198  TRP A HD1  1 c 
ATOM   2952 H HE1  . TRP A 1 183 ? 2.335   -10.172 -6.987  1.000 13.846 0 198  TRP A HE1  1 c 
ATOM   2953 H HE3  . TRP A 1 183 ? 4.686   -5.656  -7.516  1.000 12.072 0 198  TRP A HE3  1 c 
ATOM   2954 H HZ2  . TRP A 1 183 ? 1.854   -8.362  -4.910  1.000 13.462 0 198  TRP A HZ2  1 c 
ATOM   2955 H HZ3  . TRP A 1 183 ? 3.795   -4.878  -5.484  1.000 12.986 0 198  TRP A HZ3  1 c 
ATOM   2956 H HH2  . TRP A 1 183 ? 2.417   -6.230  -4.245  1.000 13.287 0 198  TRP A HH2  1 c 
ATOM   2957 N N    . HIS A 1 184 ? 3.501   -9.061  -12.114 1.000 10.981 0 199  HIS A N    1 ? 
ATOM   2958 C CA   . HIS A 1 184 ? 2.508   -10.055 -12.517 1.000 10.217 0 199  HIS A CA   1 ? 
ATOM   2959 C C    . HIS A 1 184 ? 2.985   -11.429 -12.110 1.000 11.867 0 199  HIS A C    1 ? 
ATOM   2960 O O    . HIS A 1 184 ? 4.079   -11.794 -12.506 1.000 14.951 0 199  HIS A O    1 ? 
ATOM   2961 C CB   . HIS A 1 184 ? 2.225   -9.989  -14.016 1.000 10.369 0 199  HIS A CB   1 ? 
ATOM   2962 C CG   . HIS A 1 184 ? 1.244   -11.053 -14.407 1.000 10.407 0 199  HIS A CG   1 ? 
ATOM   2963 N ND1  . HIS A 1 184 ? 1.640   -12.167 -15.149 1.000 11.717 0 199  HIS A ND1  1 ? 
ATOM   2964 C CD2  . HIS A 1 184 ? -0.047  -11.194 -14.114 1.000 9.720  0 199  HIS A CD2  1 ? 
ATOM   2965 C CE1  . HIS A 1 184 ? 0.566   -12.972 -15.246 1.000 10.236 0 199  HIS A CE1  1 ? 
ATOM   2966 N NE2  . HIS A 1 184 ? -0.469  -12.415 -14.648 1.000 10.177 0 199  HIS A NE2  1 ? 
ATOM   2967 H H    . HIS A 1 184 ? 4.375   -9.190  -12.347 1.000 10.620 0 199  HIS A H    1 c 
ATOM   2968 H HA   . HIS A 1 184 ? 1.667   -9.865  -12.035 1.000 10.710 0 199  HIS A HA   1 c 
ATOM   2969 H HB2  . HIS A 1 184 ? 1.855   -9.108  -14.236 1.000 10.339 0 199  HIS A HB2  1 c 
ATOM   2970 H HB3  . HIS A 1 184 ? 3.064   -10.121 -14.509 1.000 10.342 0 199  HIS A HB3  1 c 
ATOM   2971 H HD1  . HIS A 1 184 ? 2.460   -12.325 -15.433 0.000 11.720 0 199  HIS A HD1  1 c 
ATOM   2972 H HD2  . HIS A 1 184 ? -0.574  -10.603 -13.613 1.000 9.983  0 199  HIS A HD2  1 c 
ATOM   2973 H HE1  . HIS A 1 184 ? 0.551   -13.781 -15.717 1.000 10.511 0 199  HIS A HE1  1 c 
ATOM   2974 H HE2  . HIS A 1 184 ? -1.272  -12.764 -14.591 0.000 10.170 0 199  HIS A HE2  1 c 
ATOM   2975 N N    . GLY A 1 185 ? 2.125   -12.153 -11.400 1.000 13.734 0 200  GLY A N    1 ? 
ATOM   2976 C CA   . GLY A 1 185 ? 2.365   -13.535 -11.061 1.000 16.043 0 200  GLY A CA   1 ? 
ATOM   2977 C C    . GLY A 1 185 ? 3.530   -13.643 -10.094 1.000 18.507 0 200  GLY A C    1 ? 
ATOM   2978 O O    . GLY A 1 185 ? 3.848   -12.682 -9.402  1.000 22.124 0 200  GLY A O    1 ? 
ATOM   2979 H H    . GLY A 1 185 ? 1.350   -11.764 -11.112 1.000 13.683 0 200  GLY A H    1 c 
ATOM   2980 H HA2  . GLY A 1 185 ? 1.554   -13.916 -10.650 1.000 16.047 0 200  GLY A HA2  1 c 
ATOM   2981 H HA3  . GLY A 1 185 ? 2.563   -14.043 -11.882 1.000 16.008 0 200  GLY A HA3  1 c 
ATOM   2982 N N    . LYS A 1 186 ? 4.153   -14.824 -10.082 1.000 21.310 0 201  LYS A N    1 ? 
ATOM   2983 C CA   . LYS A 1 186 ? 5.228   -15.139 -9.157  1.000 26.205 0 201  LYS A CA   1 ? 
ATOM   2984 C C    . LYS A 1 186 ? 6.354   -15.682 -10.018 1.000 30.808 0 201  LYS A C    1 ? 
ATOM   2985 O O    . LYS A 1 186 ? 6.114   -16.514 -10.893 1.000 33.788 0 201  LYS A O    1 ? 
ATOM   2986 C CB   . LYS A 1 186 ? 4.796   -16.204 -8.132  1.000 30.242 0 201  LYS A CB   1 ? 
ATOM   2987 H H    . LYS A 1 186 ? 3.892   -15.466 -10.678 1.000 21.550 0 201  LYS A H    1 c 
ATOM   2988 H HA   . LYS A 1 186 ? 5.523   -14.311 -8.700  1.000 26.594 0 201  LYS A HA   1 c 
ATOM   2989 H HB2  . LYS A 1 186 ? 4.552   -17.023 -8.614  1.000 29.014 0 201  LYS A HB2  1 c 
ATOM   2990 H HB3  . LYS A 1 186 ? 5.557   -16.415 -7.554  0.000 30.200 0 201  LYS A HB3  1 c 
ATOM   2991 N N    . GLY A 1 187 ? 7.553   -15.144 -9.812  1.000 34.029 0 202  GLY A N    1 ? 
ATOM   2992 C CA   . GLY A 1 187 ? 8.728   -15.636 -10.512 1.000 37.332 0 202  GLY A CA   1 ? 
ATOM   2993 C C    . GLY A 1 187 ? 8.760   -15.162 -11.962 1.000 37.294 0 202  GLY A C    1 ? 
ATOM   2994 O O    . GLY A 1 187 ? 9.398   -15.780 -12.814 1.000 40.818 0 202  GLY A O    1 ? 
ATOM   2995 H H    . GLY A 1 187 ? 7.647   -14.453 -9.221  1.000 33.842 0 202  GLY A H    1 c 
ATOM   2996 H HA2  . GLY A 1 187 ? 9.536   -15.320 -10.046 1.000 36.499 0 202  GLY A HA2  1 c 
ATOM   2997 H HA3  . GLY A 1 187 ? 8.729   -16.622 -10.488 1.000 36.460 0 202  GLY A HA3  1 c 
ATOM   2998 N N    . ASN A 1 188 ? 8.063   -14.057 -12.234 1.000 28.389 0 203  ASN A N    1 ? 
ATOM   2999 C CA   . ASN A 1 188 ? 8.248   -13.339 -13.480 1.000 27.915 0 203  ASN A CA   1 ? 
ATOM   3000 C C    . ASN A 1 188 ? 9.154   -12.144 -13.174 1.000 24.130 0 203  ASN A C    1 ? 
ATOM   3001 O O    . ASN A 1 188 ? 9.233   -11.702 -12.030 1.000 31.028 0 203  ASN A O    1 ? 
ATOM   3002 C CB   . ASN A 1 188 ? 6.896   -13.030 -14.131 1.000 24.857 0 203  ASN A CB   1 ? 
ATOM   3003 C CG   . ASN A 1 188 ? 6.031   -14.249 -14.387 1.000 29.994 0 203  ASN A CG   1 ? 
ATOM   3004 O OD1  . ASN A 1 188 ? 6.473   -15.248 -14.976 1.000 29.690 0 203  ASN A OD1  1 ? 
ATOM   3005 N ND2  . ASN A 1 188 ? 4.778   -14.197 -13.951 1.000 24.883 0 203  ASN A ND2  1 ? 
ATOM   3006 H H    . ASN A 1 188 ? 7.458   -13.737 -11.629 1.000 30.264 0 203  ASN A H    1 c 
ATOM   3007 H HA   . ASN A 1 188 ? 8.734   -13.928 -14.100 1.000 26.818 0 203  ASN A HA   1 c 
ATOM   3008 H HB2  . ASN A 1 188 ? 6.407   -12.411 -13.554 1.000 26.545 0 203  ASN A HB2  1 c 
ATOM   3009 H HB3  . ASN A 1 188 ? 7.056   -12.576 -14.983 1.000 26.626 0 203  ASN A HB3  1 c 
ATOM   3010 H HD21 . ASN A 1 188 ? 4.430   -13.427 -13.679 1.000 26.232 0 203  ASN A HD21 1 c 
ATOM   3011 H HD22 . ASN A 1 188 ? 4.287   -14.937 -13.933 1.000 26.351 0 203  ASN A HD22 1 c 
ATOM   3012 N N    . GLU A 1 189 ? 9.882   -11.646 -14.176 1.000 28.877 0 204  GLU A N    1 ? 
ATOM   3013 C CA   . GLU A 1 189 ? 10.707  -10.452 -14.013 1.000 30.121 0 204  GLU A CA   1 ? 
ATOM   3014 C C    . GLU A 1 189 ? 9.886   -9.169  -14.164 1.000 25.203 0 204  GLU A C    1 ? 
ATOM   3015 O O    . GLU A 1 189 ? 9.067   -9.102  -15.095 1.000 34.213 0 204  GLU A O    1 ? 
ATOM   3016 C CB   . GLU A 1 189 ? 11.728  -10.330 -15.134 1.000 36.580 0 204  GLU A CB   1 ? 
ATOM   3017 C CG   . GLU A 1 189 ? 12.834  -11.370 -15.086 1.000 38.047 0 204  GLU A CG   1 ? 
ATOM   3018 C CD   . GLU A 1 189 ? 13.838  -10.877 -16.099 1.000 38.791 0 204  GLU A CD   1 ? 
ATOM   3019 O OE1  . GLU A 1 189 ? 13.470  -10.513 -17.244 1.000 43.440 0 204  GLU A OE1  1 ? 
ATOM   3020 O OE2  . GLU A 1 189 ? 14.993  -10.801 -15.710 1.000 25.702 0 204  GLU A OE2  1 ? 
ATOM   3021 H H    . GLU A 1 189 ? 9.866   -12.062 -14.989 1.000 28.016 0 204  GLU A H    1 c 
ATOM   3022 H HA   . GLU A 1 189 ? 11.152  -10.474 -13.129 1.000 29.939 0 204  GLU A HA   1 c 
ATOM   3023 H HB2  . GLU A 1 189 ? 11.260  -10.406 -15.992 1.000 35.229 0 204  GLU A HB2  1 c 
ATOM   3024 H HB3  . GLU A 1 189 ? 12.133  -9.437  -15.095 1.000 35.239 0 204  GLU A HB3  1 c 
ATOM   3025 H HG2  . GLU A 1 189 ? 13.240  -11.403 -14.194 1.000 37.781 0 204  GLU A HG2  1 c 
ATOM   3026 H HG3  . GLU A 1 189 ? 12.494  -12.252 -15.347 1.000 37.860 0 204  GLU A HG3  1 c 
ATOM   3027 N N    . ASP A 1 190 ? 10.163  -8.180  -13.284 1.000 31.905 0 205  ASP A N    1 ? 
ATOM   3028 C CA   . ASP A 1 190 ? 9.522   -6.860  -13.261 1.000 32.366 0 205  ASP A CA   1 ? 
ATOM   3029 C C    . ASP A 1 190 ? 9.684   -6.229  -14.660 1.000 28.855 0 205  ASP A C    1 ? 
ATOM   3030 O O    . ASP A 1 190 ? 10.712  -6.390  -15.320 1.000 28.932 0 205  ASP A O    1 ? 
ATOM   3031 C CB   . ASP A 1 190 ? 10.063  -6.120  -12.029 1.000 33.639 0 205  ASP A CB   1 ? 
ATOM   3032 C CG   . ASP A 1 190 ? 9.578   -4.721  -11.655 1.000 32.609 0 205  ASP A CG   1 ? 
ATOM   3033 O OD1  . ASP A 1 190 ? 9.661   -3.838  -12.516 1.000 27.637 0 205  ASP A OD1  1 ? 
ATOM   3034 O OD2  . ASP A 1 190 ? 9.275   -4.463  -10.451 1.000 26.190 0 205  ASP A OD2  1 ? 
ATOM   3035 H H    . ASP A 1 190 ? 10.804  -8.348  -12.654 1.000 30.313 0 205  ASP A H    1 c 
ATOM   3036 H HA   . ASP A 1 190 ? 8.561   -6.998  -13.100 1.000 31.767 0 205  ASP A HA   1 c 
ATOM   3037 H HB2  . ASP A 1 190 ? 9.884   -6.694  -11.256 1.000 33.033 0 205  ASP A HB2  1 c 
ATOM   3038 H HB3  . ASP A 1 190 ? 11.036  -6.065  -12.126 1.000 33.073 0 205  ASP A HB3  1 c 
ATOM   3039 N N    . ARG A 1 191 ? 8.630   -5.584  -15.177 1.000 22.662 0 206  ARG A N    1 ? 
ATOM   3040 C CA   . ARG A 1 191 ? 8.734   -4.810  -16.421 1.000 19.156 0 206  ARG A CA   1 ? 
ATOM   3041 C C    . ARG A 1 191 ? 8.221   -3.401  -16.162 1.000 15.420 0 206  ARG A C    1 ? 
ATOM   3042 O O    . ARG A 1 191 ? 7.782   -2.707  -17.093 1.000 15.266 0 206  ARG A O    1 ? 
ATOM   3043 C CB   . ARG A 1 191 ? 8.009   -5.476  -17.603 1.000 22.295 0 206  ARG A CB   1 ? 
ATOM   3044 C CG   . ARG A 1 191 ? 8.653   -6.704  -18.246 1.000 27.650 0 206  ARG A CG   1 ? 
ATOM   3045 C CD   . ARG A 1 191 ? 8.141   -7.001  -19.666 1.000 30.553 0 206  ARG A CD   1 ? 
ATOM   3046 N NE   . ARG A 1 191 ? 6.735   -7.425  -19.728 1.000 30.431 0 206  ARG A NE   1 ? 
ATOM   3047 C CZ   . ARG A 1 191 ? 6.217   -8.575  -19.250 1.000 35.898 0 206  ARG A CZ   1 ? 
ATOM   3048 N NH1  . ARG A 1 191 ? 6.997   -9.565  -18.833 1.000 34.289 0 206  ARG A NH1  1 ? 
ATOM   3049 N NH2  . ARG A 1 191 ? 4.906   -8.773  -19.207 1.000 35.838 0 206  ARG A NH2  1 ? 
ATOM   3050 H H    . ARG A 1 191 ? 7.823   -5.625  -14.750 1.000 23.112 0 206  ARG A H    1 c 
ATOM   3051 H HA   . ARG A 1 191 ? 9.693   -4.742  -16.662 1.000 19.634 0 206  ARG A HA   1 c 
ATOM   3052 H HB2  . ARG A 1 191 ? 7.113   -5.730  -17.297 1.000 22.617 0 206  ARG A HB2  1 c 
ATOM   3053 H HB3  . ARG A 1 191 ? 7.892   -4.799  -18.303 1.000 22.567 0 206  ARG A HB3  1 c 
ATOM   3054 H HG2  . ARG A 1 191 ? 9.625   -6.573  -18.282 1.000 26.960 0 206  ARG A HG2  1 c 
ATOM   3055 H HG3  . ARG A 1 191 ? 8.481   -7.487  -17.679 1.000 26.932 0 206  ARG A HG3  1 c 
ATOM   3056 H HD2  . ARG A 1 191 ? 8.250   -6.194  -20.208 1.000 29.733 0 206  ARG A HD2  1 c 
ATOM   3057 H HD3  . ARG A 1 191 ? 8.702   -7.698  -20.061 1.000 29.857 0 206  ARG A HD3  1 c 
ATOM   3058 H HE   . ARG A 1 191 ? 6.176   -6.880  -20.113 1.000 31.733 0 206  ARG A HE   1 c 
ATOM   3059 H HH11 . ARG A 1 191 ? 6.681   -10.159 -18.253 1.000 34.776 0 206  ARG A HH11 1 c 
ATOM   3060 H HH12 . ARG A 1 191 ? 7.828   -9.633  -19.136 1.000 34.706 0 206  ARG A HH12 1 c 
ATOM   3061 H HH21 . ARG A 1 191 ? 4.585   -9.566  -18.982 1.000 35.816 0 206  ARG A HH21 1 c 
ATOM   3062 H HH22 . ARG A 1 191 ? 4.355   -8.110  -19.405 1.000 35.772 0 206  ARG A HH22 1 c 
ATOM   3063 N N    . ARG A 1 192 ? 8.254   -2.937  -14.911 1.000 15.181 0 207  ARG A N    1 ? 
ATOM   3064 C CA   . ARG A 1 192 ? 7.711   -1.662  -14.512 1.000 15.139 0 207  ARG A CA   1 ? 
ATOM   3065 C C    . ARG A 1 192 ? 8.357   -0.546  -15.351 1.000 15.332 0 207  ARG A C    1 ? 
ATOM   3066 O O    . ARG A 1 192 ? 9.576   -0.546  -15.601 1.000 19.573 0 207  ARG A O    1 ? 
ATOM   3067 C CB   . ARG A 1 192 ? 7.820   -1.397  -12.996 1.000 15.793 0 207  ARG A CB   1 ? 
ATOM   3068 C CG   . ARG A 1 192 ? 6.945   -2.329  -12.162 1.000 16.578 0 207  ARG A CG   1 ? 
ATOM   3069 C CD   . ARG A 1 192 ? 6.818   -1.949  -10.664 1.000 18.492 0 207  ARG A CD   1 ? 
ATOM   3070 N NE   . ARG A 1 192 ? 8.106   -1.753  -10.015 1.000 19.964 0 207  ARG A NE   1 ? 
ATOM   3071 C CZ   . ARG A 1 192 ? 8.709   -0.627  -9.689  1.000 19.692 0 207  ARG A CZ   1 ? 
ATOM   3072 N NH1  . ARG A 1 192 ? 8.075   0.577   -9.628  1.000 16.372 0 207  ARG A NH1  1 ? 
ATOM   3073 N NH2  . ARG A 1 192 ? 10.004  -0.765  -9.425  1.000 23.687 0 207  ARG A NH2  1 ? 
ATOM   3074 H H    . ARG A 1 192 ? 8.653   -3.450  -14.269 1.000 15.353 0 207  ARG A H    1 c 
ATOM   3075 H HA   . ARG A 1 192 ? 6.744   -1.677  -14.726 1.000 15.220 0 207  ARG A HA   1 c 
ATOM   3076 H HB2  . ARG A 1 192 ? 8.755   -1.502  -12.718 1.000 15.872 0 207  ARG A HB2  1 c 
ATOM   3077 H HB3  . ARG A 1 192 ? 7.556   -0.470  -12.816 1.000 15.829 0 207  ARG A HB3  1 c 
ATOM   3078 H HG2  . ARG A 1 192 ? 6.045   -2.347  -12.554 1.000 16.813 0 207  ARG A HG2  1 c 
ATOM   3079 H HG3  . ARG A 1 192 ? 7.300   -3.240  -12.225 1.000 16.911 0 207  ARG A HG3  1 c 
ATOM   3080 H HD2  . ARG A 1 192 ? 6.294   -1.127  -10.590 1.000 18.214 0 207  ARG A HD2  1 c 
ATOM   3081 H HD3  . ARG A 1 192 ? 6.330   -2.657  -10.198 1.000 18.343 0 207  ARG A HD3  1 c 
ATOM   3082 H HE   . ARG A 1 192 ? 8.537   -2.481  -9.806  1.000 19.598 0 207  ARG A HE   1 c 
ATOM   3083 H HH11 . ARG A 1 192 ? 8.490   1.306   -9.909  1.000 17.332 0 207  ARG A HH11 1 c 
ATOM   3084 H HH12 . ARG A 1 192 ? 7.253   0.625   -9.307  1.000 17.337 0 207  ARG A HH12 1 c 
ATOM   3085 H HH21 . ARG A 1 192 ? 10.387  -0.234  -8.828  1.000 22.365 0 207  ARG A HH21 1 c 
ATOM   3086 H HH22 . ARG A 1 192 ? 10.482  -1.381  -9.847  1.000 22.329 0 207  ARG A HH22 1 c 
ATOM   3087 N N    . GLY A 1 193 ? 7.501   0.342   -15.817 1.000 14.603 0 208  GLY A N    1 ? 
ATOM   3088 C CA   . GLY A 1 193 ? 7.990   1.422   -16.657 1.000 14.090 0 208  GLY A CA   1 ? 
ATOM   3089 C C    . GLY A 1 193 ? 7.862   1.142   -18.151 1.000 12.810 0 208  GLY A C    1 ? 
ATOM   3090 O O    . GLY A 1 193 ? 7.882   2.120   -18.936 1.000 13.818 0 208  GLY A O    1 ? 
ATOM   3091 H H    . GLY A 1 193 ? 6.610   0.290   -15.618 1.000 14.636 0 208  GLY A H    1 c 
ATOM   3092 H HA2  . GLY A 1 193 ? 7.485   2.237   -16.441 1.000 14.045 0 208  GLY A HA2  1 c 
ATOM   3093 H HA3  . GLY A 1 193 ? 8.936   1.595   -16.440 1.000 13.975 0 208  GLY A HA3  1 c 
ATOM   3094 N N    . GLN A 1 194 ? 7.804   -0.122  -18.569 1.000 12.577 0 209  GLN A N    1 ? 
ATOM   3095 C CA   . GLN A 1 194 ? 7.727   -0.462  -19.988 1.000 11.350 0 209  GLN A CA   1 ? 
ATOM   3096 C C    . GLN A 1 194 ? 6.283   -0.393  -20.479 1.000 10.250 0 209  GLN A C    1 ? 
ATOM   3097 O O    . GLN A 1 194 ? 5.308   -0.452  -19.716 1.000 11.091 0 209  GLN A O    1 ? 
ATOM   3098 C CB   . GLN A 1 194 ? 8.234   -1.884  -20.205 1.000 13.625 0 209  GLN A CB   1 ? 
ATOM   3099 C CG   . GLN A 1 194 ? 9.737   -2.004  -19.945 1.000 19.338 0 209  GLN A CG   1 ? 
ATOM   3100 C CD   . GLN A 1 194 ? 10.258  -3.409  -20.018 1.000 20.300 0 209  GLN A CD   1 ? 
ATOM   3101 O OE1  . GLN A 1 194 ? 11.000  -3.850  -19.115 1.000 30.149 0 209  GLN A OE1  1 ? 
ATOM   3102 N NE2  . GLN A 1 194 ? 9.889   -4.118  -21.057 1.000 22.784 0 209  GLN A NE2  1 ? 
ATOM   3103 H H    . GLN A 1 194 ? 7.813   -0.800  -17.957 1.000 12.406 0 209  GLN A H    1 c 
ATOM   3104 H HA   . GLN A 1 194 ? 8.282   0.177   -20.504 1.000 11.750 0 209  GLN A HA   1 c 
ATOM   3105 H HB2  . GLN A 1 194 ? 7.752   -2.494  -19.609 1.000 14.158 0 209  GLN A HB2  1 c 
ATOM   3106 H HB3  . GLN A 1 194 ? 8.045   -2.153  -21.128 1.000 14.184 0 209  GLN A HB3  1 c 
ATOM   3107 H HG2  . GLN A 1 194 ? 10.217  -1.458  -20.600 1.000 18.064 0 209  GLN A HG2  1 c 
ATOM   3108 H HG3  . GLN A 1 194 ? 9.939   -1.643  -19.056 1.000 18.086 0 209  GLN A HG3  1 c 
ATOM   3109 H HE21 . GLN A 1 194 ? 9.601   -3.718  -21.794 1.000 21.849 0 209  GLN A HE21 1 c 
ATOM   3110 H HE22 . GLN A 1 194 ? 9.941   -5.002  -21.026 1.000 22.063 0 209  GLN A HE22 1 c 
ATOM   3111 N N    . THR A 1 195 ? 6.136   -0.359  -21.787 1.000 9.803  0 210  THR A N    1 ? 
ATOM   3112 C CA   . THR A 1 195 ? 4.833   -0.521  -22.435 1.000 9.204  0 210  THR A CA   1 ? 
ATOM   3113 C C    . THR A 1 195 ? 4.366   -1.970  -22.336 1.000 8.712  0 210  THR A C    1 ? 
ATOM   3114 O O    . THR A 1 195 ? 5.143   -2.873  -22.059 1.000 8.683  0 210  THR A O    1 ? 
ATOM   3115 C CB   . THR A 1 195 ? 4.844   -0.110  -23.900 1.000 10.147 0 210  THR A CB   1 ? 
ATOM   3116 O OG1  . THR A 1 195 ? 5.447   -1.144  -24.696 1.000 11.851 0 210  THR A OG1  1 ? 
ATOM   3117 C CG2  . THR A 1 195 ? 5.582   1.180   -24.138 1.000 11.051 0 210  THR A CG2  1 ? 
ATOM   3118 H H    . THR A 1 195 ? 6.877   -0.250  -22.311 1.000 9.811  0 210  THR A H    1 c 
ATOM   3119 H HA   . THR A 1 195 ? 4.186   0.046   -21.964 1.000 9.402  0 210  THR A HA   1 c 
ATOM   3120 H HB   . THR A 1 195 ? 3.912   0.016   -24.198 1.000 10.412 0 210  THR A HB   1 c 
ATOM   3121 H HG1  . THR A 1 195 ? 6.259   -1.275  -24.432 0.000 11.850 0 210  THR A HG1  1 c 
ATOM   3122 H HG21 . THR A 1 195 ? 5.398   1.497   -25.038 1.000 10.770 0 210  THR A HG21 1 c 
ATOM   3123 H HG22 . THR A 1 195 ? 6.536   1.033   -24.036 1.000 10.760 0 210  THR A HG22 1 c 
ATOM   3124 H HG23 . THR A 1 195 ? 5.286   1.846   -23.494 1.000 10.770 0 210  THR A HG23 1 c 
ATOM   3125 N N    . VAL A 1 196 ? 3.105   -2.186  -22.765 1.000 8.464  0 211  VAL A N    1 ? 
ATOM   3126 C CA   . VAL A 1 196 ? 2.551   -3.522  -22.946 1.000 8.232  0 211  VAL A CA   1 ? 
ATOM   3127 C C    . VAL A 1 196 ? 2.551   -3.987  -24.396 1.000 8.961  0 211  VAL A C    1 ? 
ATOM   3128 O O    . VAL A 1 196 ? 1.937   -4.987  -24.745 1.000 8.610  0 211  VAL A O    1 ? 
ATOM   3129 C CB   . VAL A 1 196 ? 1.122   -3.610  -22.354 1.000 8.293  0 211  VAL A CB   1 ? 
ATOM   3130 C CG1  . VAL A 1 196 ? 1.115   -3.249  -20.882 1.000 8.478  0 211  VAL A CG1  1 ? 
ATOM   3131 C CG2  . VAL A 1 196 ? 0.079   -2.842  -23.151 1.000 8.945  0 211  VAL A CG2  1 ? 
ATOM   3132 H H    . VAL A 1 196 ? 2.573   -1.466  -22.946 1.000 8.500  0 211  VAL A H    1 c 
ATOM   3133 H HA   . VAL A 1 196 ? 3.112   -4.142  -22.442 1.000 8.434  0 211  VAL A HA   1 c 
ATOM   3134 H HB   . VAL A 1 196 ? 0.861   -4.558  -22.404 1.000 8.437  0 211  VAL A HB   1 c 
ATOM   3135 H HG11 . VAL A 1 196 ? 1.324   -2.305  -20.777 1.000 8.422  0 211  VAL A HG11 1 c 
ATOM   3136 H HG12 . VAL A 1 196 ? 1.781   -3.781  -20.414 1.000 8.422  0 211  VAL A HG12 1 c 
ATOM   3137 H HG13 . VAL A 1 196 ? 0.237   -3.429  -20.507 1.000 8.419  0 211  VAL A HG13 1 c 
ATOM   3138 H HG21 . VAL A 1 196 ? -0.761  -2.837  -22.663 1.000 8.749  0 211  VAL A HG21 1 c 
ATOM   3139 H HG22 . VAL A 1 196 ? -0.053  -3.270  -24.014 1.000 8.750  0 211  VAL A HG22 1 c 
ATOM   3140 H HG23 . VAL A 1 196 ? 0.379   -1.928  -23.285 1.000 8.752  0 211  VAL A HG23 1 c 
ATOM   3141 N N    . ASN A 1 197 ? 3.298   -3.311  -25.291 1.000 9.492  0 212  ASN A N    1 ? 
ATOM   3142 C CA   . ASN A 1 197 ? 3.210   -3.602  -26.718 1.000 10.537 0 212  ASN A CA   1 ? 
ATOM   3143 C C    . ASN A 1 197 ? 3.735   -4.979  -27.121 1.000 9.858  0 212  ASN A C    1 ? 
ATOM   3144 O O    . ASN A 1 197 ? 3.157   -5.572  -28.036 1.000 9.850  0 212  ASN A O    1 ? 
ATOM   3145 C CB   . ASN A 1 197 ? 3.966   -2.578  -27.532 1.000 12.012 0 212  ASN A CB   1 ? 
ATOM   3146 C CG   . ASN A 1 197 ? 3.295   -1.259  -27.462 1.000 14.084 0 212  ASN A CG   1 ? 
ATOM   3147 O OD1  . ASN A 1 197 ? 2.066   -1.158  -27.509 1.000 15.934 0 212  ASN A OD1  1 ? 
ATOM   3148 N ND2  . ASN A 1 197 ? 4.136   -0.225  -27.394 1.000 15.648 0 212  ASN A ND2  1 ? 
ATOM   3149 H H    . ASN A 1 197 ? 3.878   -2.665  -25.006 1.000 9.595  0 212  ASN A H    1 c 
ATOM   3150 H HA   . ASN A 1 197 ? 2.264   -3.550  -26.980 1.000 10.475 0 212  ASN A HA   1 c 
ATOM   3151 H HB2  . ASN A 1 197 ? 4.879   -2.501  -27.189 1.000 12.138 0 212  ASN A HB2  1 c 
ATOM   3152 H HB3  . ASN A 1 197 ? 4.011   -2.869  -28.464 1.000 12.095 0 212  ASN A HB3  1 c 
ATOM   3153 H HD21 . ASN A 1 197 ? 5.010   -0.347  -27.486 1.000 15.091 0 212  ASN A HD21 1 c 
ATOM   3154 H HD22 . ASN A 1 197 ? 3.816   0.591   -27.257 1.000 15.135 0 212  ASN A HD22 1 c 
ATOM   3155 N N    . ALA A 1 198 ? 4.784   -5.475  -26.485 1.000 10.528 0 213  ALA A N    1 ? 
ATOM   3156 C CA   . ALA A 1 198 ? 5.286   -6.804  -26.810 1.000 11.426 0 213  ALA A CA   1 ? 
ATOM   3157 C C    . ALA A 1 198 ? 4.221   -7.847  -26.498 1.000 10.978 0 213  ALA A C    1 ? 
ATOM   3158 O O    . ALA A 1 198 ? 3.988   -8.753  -27.296 1.000 10.566 0 213  ALA A O    1 ? 
ATOM   3159 C CB   . ALA A 1 198 ? 6.567   -7.169  -26.060 1.000 13.249 0 213  ALA A CB   1 ? 
ATOM   3160 H H    . ALA A 1 198 ? 5.203   -4.984  -25.838 1.000 10.564 0 213  ALA A H    1 c 
ATOM   3161 H HA   . ALA A 1 198 ? 5.468   -6.833  -27.790 1.000 11.449 0 213  ALA A HA   1 c 
ATOM   3162 H HB1  . ALA A 1 198 ? 7.267   -6.531  -26.279 1.000 12.683 0 213  ALA A HB1  1 c 
ATOM   3163 H HB2  . ALA A 1 198 ? 6.403   -7.149  -25.103 1.000 12.683 0 213  ALA A HB2  1 c 
ATOM   3164 H HB3  . ALA A 1 198 ? 6.854   -8.061  -26.319 1.000 12.675 0 213  ALA A HB3  1 c 
ATOM   3165 N N    . GLY A 1 199 ? 3.531   -7.671  -25.363 1.000 9.686  0 214  GLY A N    1 ? 
ATOM   3166 C CA   . GLY A 1 199 ? 2.487   -8.624  -24.969 1.000 9.540  0 214  GLY A CA   1 ? 
ATOM   3167 C C    . GLY A 1 199 ? 1.283   -8.587  -25.883 1.000 9.239  0 214  GLY A C    1 ? 
ATOM   3168 O O    . GLY A 1 199 ? 0.722   -9.629  -26.220 1.000 9.572  0 214  GLY A O    1 ? 
ATOM   3169 H H    . GLY A 1 199 ? 3.711   -6.958  -24.821 1.000 9.960  0 214  GLY A H    1 c 
ATOM   3170 H HA2  . GLY A 1 199 ? 2.869   -9.533  -24.968 1.000 9.551  0 214  GLY A HA2  1 c 
ATOM   3171 H HA3  . GLY A 1 199 ? 2.203   -8.418  -24.049 1.000 9.507  0 214  GLY A HA3  1 c 
ATOM   3172 N N    . VAL A 1 200 ? 0.875   -7.386  -26.305 1.000 7.972  0 215  VAL A N    1 ? 
ATOM   3173 C CA   . VAL A 1 200 ? -0.178  -7.255  -27.296 1.000 8.304  0 215  VAL A CA   1 ? 
ATOM   3174 C C    . VAL A 1 200 ? 0.223   -7.965  -28.598 1.000 9.044  0 215  VAL A C    1 ? 
ATOM   3175 O O    . VAL A 1 200 ? -0.541  -8.738  -29.185 1.000 9.977  0 215  VAL A O    1 ? 
ATOM   3176 C CB   . VAL A 1 200 ? -0.581  -5.782  -27.513 1.000 7.925  0 215  VAL A CB   1 ? 
ATOM   3177 C CG1  . VAL A 1 200 ? -1.533  -5.608  -28.660 1.000 8.346  0 215  VAL A CG1  1 ? 
ATOM   3178 C CG2  . VAL A 1 200 ? -1.196  -5.198  -26.261 1.000 8.488  0 215  VAL A CG2  1 ? 
ATOM   3179 H H    . VAL A 1 200 ? 1.262   -6.630  -25.966 1.000 8.347  0 215  VAL A H    1 c 
ATOM   3180 H HA   . VAL A 1 200 ? -0.962  -7.718  -26.944 1.000 8.310  0 215  VAL A HA   1 c 
ATOM   3181 H HB   . VAL A 1 200 ? 0.242   -5.279  -27.716 1.000 8.176  0 215  VAL A HB   1 c 
ATOM   3182 H HG11 . VAL A 1 200 ? -2.258  -6.250  -28.581 1.000 8.217  0 215  VAL A HG11 1 c 
ATOM   3183 H HG12 . VAL A 1 200 ? -1.063  -5.752  -29.498 1.000 8.222  0 215  VAL A HG12 1 c 
ATOM   3184 H HG13 . VAL A 1 200 ? -1.898  -4.706  -28.647 1.000 8.221  0 215  VAL A HG13 1 c 
ATOM   3185 H HG21 . VAL A 1 200 ? -1.425  -4.266  -26.416 1.000 8.316  0 215  VAL A HG21 1 c 
ATOM   3186 H HG22 . VAL A 1 200 ? -0.562  -5.256  -25.528 1.000 8.316  0 215  VAL A HG22 1 c 
ATOM   3187 H HG23 . VAL A 1 200 ? -2.000  -5.694  -26.033 1.000 8.316  0 215  VAL A HG23 1 c 
ATOM   3188 N N    . ALA A 1 201 ? 1.439   -7.646  -29.071 1.000 9.277  0 216  ALA A N    1 ? 
ATOM   3189 C CA   . ALA A 1 201 ? 1.933   -8.129  -30.359 1.000 10.096 0 216  ALA A CA   1 ? 
ATOM   3190 C C    . ALA A 1 201 ? 2.024   -9.659  -30.351 1.000 10.486 0 216  ALA A C    1 ? 
ATOM   3191 O O    . ALA A 1 201 ? 1.813   -10.279 -31.415 1.000 12.352 0 216  ALA A O    1 ? 
ATOM   3192 C CB   . ALA A 1 201 ? 3.303   -7.525  -30.685 1.000 10.630 0 216  ALA A CB   1 ? 
ATOM   3193 H H    . ALA A 1 201 ? 1.980   -7.102  -28.573 1.000 9.388  0 216  ALA A H    1 c 
ATOM   3194 H HA   . ALA A 1 201 ? 1.283   -7.859  -31.063 1.000 10.094 0 216  ALA A HA   1 c 
ATOM   3195 H HB1  . ALA A 1 201 ? 3.232   -6.556  -30.724 1.000 10.471 0 216  ALA A HB1  1 c 
ATOM   3196 H HB2  . ALA A 1 201 ? 3.943   -7.772  -29.997 1.000 10.471 0 216  ALA A HB2  1 c 
ATOM   3197 H HB3  . ALA A 1 201 ? 3.612   -7.858  -31.545 1.000 10.471 0 216  ALA A HB3  1 c 
ATOM   3198 N N    . GLU A 1 202 ? 2.341   -10.297 -29.228 1.000 10.205 0 217  GLU A N    1 ? 
ATOM   3199 C CA   . GLU A 1 202 ? 2.468   -11.754 -29.218 1.000 11.458 0 217  GLU A CA   1 ? 
ATOM   3200 C C    . GLU A 1 202 ? 1.131   -12.466 -29.096 1.000 11.164 0 217  GLU A C    1 ? 
ATOM   3201 O O    . GLU A 1 202 ? 1.152   -13.706 -29.096 1.000 10.910 0 217  GLU A O    1 ? 
ATOM   3202 C CB   . GLU A 1 202 ? 3.496   -12.225 -28.231 1.000 14.796 0 217  GLU A CB   1 ? 
ATOM   3203 C CG   . GLU A 1 202 ? 3.078   -12.119 -26.791 1.000 15.510 0 217  GLU A CG   1 ? 
ATOM   3204 C CD   . GLU A 1 202 ? 4.158   -12.585 -25.809 1.000 19.477 0 217  GLU A CD   1 ? 
ATOM   3205 O OE1  . GLU A 1 202 ? 5.200   -13.053 -26.251 1.000 28.298 0 217  GLU A OE1  1 ? 
ATOM   3206 O OE2  . GLU A 1 202 ? 3.955   -12.531 -24.632 1.000 22.245 0 217  GLU A OE2  1 ? 
ATOM   3207 H H    . GLU A 1 202 ? 2.488   -9.829  -28.457 1.000 10.580 0 217  GLU A H    1 c 
ATOM   3208 H HA   . GLU A 1 202 ? 2.840   -12.014 -30.099 1.000 11.713 0 217  GLU A HA   1 c 
ATOM   3209 H HB2  . GLU A 1 202 ? 3.710   -13.161 -28.426 1.000 14.144 0 217  GLU A HB2  1 c 
ATOM   3210 H HB3  . GLU A 1 202 ? 4.314   -11.701 -28.358 1.000 14.158 0 217  GLU A HB3  1 c 
ATOM   3211 H HG2  . GLU A 1 202 ? 2.854   -11.186 -26.589 1.000 16.001 0 217  GLU A HG2  1 c 
ATOM   3212 H HG3  . GLU A 1 202 ? 2.272   -12.659 -26.647 1.000 16.098 0 217  GLU A HG3  1 c 
ATOM   3213 N N    . ARG A 1 203 ? 0.042   -11.731 -28.966 1.000 9.958  0 218  ARG A N    1 ? 
ATOM   3214 C CA   . ARG A 1 203 ? -1.295  -12.315 -28.933 1.000 9.641  0 218  ARG A CA   1 ? 
ATOM   3215 C C    . ARG A 1 203 ? -1.496  -13.226 -27.728 1.000 9.250  0 218  ARG A C    1 ? 
ATOM   3216 O O    . ARG A 1 203 ? -2.271  -14.195 -27.787 1.000 10.164 0 218  ARG A O    1 ? 
ATOM   3217 C CB   . ARG A 1 203 ? -1.672  -12.980 -30.263 1.000 12.493 0 218  ARG A CB   1 ? 
ATOM   3218 C CG   . ARG A 1 203 ? -1.327  -12.164 -31.506 1.000 16.683 0 218  ARG A CG   1 ? 
ATOM   3219 C CD   . ARG A 1 203 ? -1.395  -13.095 -32.753 1.000 17.881 0 218  ARG A CD   1 ? 
ATOM   3220 N NE   . ARG A 1 203 ? -2.746  -13.622 -32.918 1.000 19.889 0 218  ARG A NE   1 ? 
ATOM   3221 C CZ   . ARG A 1 203 ? -3.752  -12.880 -33.332 1.000 20.574 0 218  ARG A CZ   1 ? 
ATOM   3222 N NH1  . ARG A 1 203 ? -3.441  -11.727 -33.877 1.000 23.830 0 218  ARG A NH1  1 ? 
ATOM   3223 N NH2  . ARG A 1 203 ? -5.007  -13.298 -33.287 1.000 19.867 0 218  ARG A NH2  1 ? 
ATOM   3224 H H    . ARG A 1 203 ? 0.121   -10.825 -28.878 1.000 10.163 0 218  ARG A H    1 c 
ATOM   3225 H HA   . ARG A 1 203 ? -1.931  -11.563 -28.827 1.000 10.107 0 218  ARG A HA   1 c 
ATOM   3226 H HB2  . ARG A 1 203 ? -1.215  -13.846 -30.319 1.000 12.633 0 218  ARG A HB2  1 c 
ATOM   3227 H HB3  . ARG A 1 203 ? -2.637  -13.155 -30.261 1.000 12.609 0 218  ARG A HB3  1 c 
ATOM   3228 H HG2  . ARG A 1 203 ? -1.969  -11.428 -31.609 1.000 15.892 0 218  ARG A HG2  1 c 
ATOM   3229 H HG3  . ARG A 1 203 ? -0.423  -11.792 -31.425 1.000 15.779 0 218  ARG A HG3  1 c 
ATOM   3230 H HD2  . ARG A 1 203 ? -1.136  -12.597 -33.556 1.000 18.127 0 218  ARG A HD2  1 c 
ATOM   3231 H HD3  . ARG A 1 203 ? -0.768  -13.839 -32.641 1.000 18.035 0 218  ARG A HD3  1 c 
ATOM   3232 H HE   . ARG A 1 203 ? -2.893  -14.461 -32.735 1.000 19.569 0 218  ARG A HE   1 c 
ATOM   3233 H HH11 . ARG A 1 203 ? -3.662  -10.974 -33.465 1.000 22.758 0 218  ARG A HH11 1 c 
ATOM   3234 H HH12 . ARG A 1 203 ? -3.016  -11.707 -34.653 1.000 22.700 0 218  ARG A HH12 1 c 
ATOM   3235 H HH21 . ARG A 1 203 ? -5.664  -12.700 -33.228 1.000 20.106 0 218  ARG A HH21 1 c 
ATOM   3236 H HH22 . ARG A 1 203 ? -5.182  -14.171 -33.313 1.000 20.083 0 218  ARG A HH22 1 c 
ATOM   3237 N N    . SER A 1 204 ? -0.882  -12.888 -26.602 1.000 8.233  0 219  SER A N    1 ? 
ATOM   3238 C CA   . SER A 1 204 ? -1.160  -13.586 -25.349 1.000 8.545  0 219  SER A CA   1 ? 
ATOM   3239 C C    . SER A 1 204 ? -2.545  -13.247 -24.788 1.000 8.213  0 219  SER A C    1 ? 
ATOM   3240 O O    . SER A 1 204 ? -3.095  -12.169 -25.020 1.000 8.856  0 219  SER A O    1 ? 
ATOM   3241 C CB   . SER A 1 204 ? -0.141  -13.263 -24.333 1.000 8.280  0 219  SER A CB   1 ? 
ATOM   3242 O OG   . SER A 1 204 ? -0.201  -11.854 -24.036 1.000 10.018 0 219  SER A OG   1 ? 
ATOM   3243 H H    . SER A 1 204 ? -0.278  -12.201 -26.602 1.000 8.563  0 219  SER A H    1 c 
ATOM   3244 H HA   . SER A 1 204 ? -1.126  -14.560 -25.524 1.000 8.394  0 219  SER A HA   1 c 
ATOM   3245 H HB2  . SER A 1 204 ? -0.309  -13.779 -23.523 1.000 8.725  0 219  SER A HB2  1 c 
ATOM   3246 H HB3  . SER A 1 204 ? 0.745   -13.491 -24.673 1.000 8.737  0 219  SER A HB3  1 c 
ATOM   3247 H HG   . SER A 1 204 ? 0.386   -11.677 -23.453 0.000 10.020 0 219  SER A HG   1 c 
ATOM   3248 N N    . TRP A 1 205 ? -3.088  -14.166 -24.000 1.000 7.819  0 220  TRP A N    1 ? 
ATOM   3249 C CA   . TRP A 1 205 ? -4.285  -13.859 -23.241 1.000 7.630  0 220  TRP A CA   1 ? 
ATOM   3250 C C    . TRP A 1 205 ? -4.044  -12.724 -22.260 1.000 6.993  0 220  TRP A C    1 ? 
ATOM   3251 O O    . TRP A 1 205 ? -4.951  -11.914 -22.040 1.000 7.395  0 220  TRP A O    1 ? 
ATOM   3252 C CB   . TRP A 1 205 ? -4.830  -15.120 -22.588 1.000 7.852  0 220  TRP A CB   1 ? 
ATOM   3253 C CG   . TRP A 1 205 ? -5.928  -14.868 -21.589 1.000 7.393  0 220  TRP A CG   1 ? 
ATOM   3254 C CD1  . TRP A 1 205 ? -7.234  -14.510 -21.805 1.000 7.708  0 220  TRP A CD1  1 ? 
ATOM   3255 C CD2  . TRP A 1 205 ? -5.792  -14.963 -20.180 1.000 7.067  0 220  TRP A CD2  1 ? 
ATOM   3256 N NE1  . TRP A 1 205 ? -7.914  -14.428 -20.614 1.000 7.684  0 220  TRP A NE1  1 ? 
ATOM   3257 C CE2  . TRP A 1 205 ? -7.060  -14.711 -19.599 1.000 6.962  0 220  TRP A CE2  1 ? 
ATOM   3258 C CE3  . TRP A 1 205 ? -4.732  -15.249 -19.315 1.000 7.186  0 220  TRP A CE3  1 ? 
ATOM   3259 C CZ2  . TRP A 1 205 ? -7.295  -14.770 -18.225 1.000 7.122  0 220  TRP A CZ2  1 ? 
ATOM   3260 C CZ3  . TRP A 1 205 ? -4.959  -15.322 -17.963 1.000 8.326  0 220  TRP A CZ3  1 ? 
ATOM   3261 C CH2  . TRP A 1 205 ? -6.228  -15.112 -17.425 1.000 7.530  0 220  TRP A CH2  1 ? 
ATOM   3262 H H    . TRP A 1 205 ? -2.715  -14.997 -23.936 1.000 7.877  0 220  TRP A H    1 c 
ATOM   3263 H HA   . TRP A 1 205 ? -4.972  -13.549 -23.888 1.000 7.595  0 220  TRP A HA   1 c 
ATOM   3264 H HB2  . TRP A 1 205 ? -5.171  -15.713 -23.291 1.000 7.694  0 220  TRP A HB2  1 c 
ATOM   3265 H HB3  . TRP A 1 205 ? -4.091  -15.582 -22.136 1.000 7.695  0 220  TRP A HB3  1 c 
ATOM   3266 H HD1  . TRP A 1 205 ? -7.631  -14.394 -22.653 1.000 7.622  0 220  TRP A HD1  1 c 
ATOM   3267 H HE1  . TRP A 1 205 ? -8.763  -14.240 -20.528 1.000 7.508  0 220  TRP A HE1  1 c 
ATOM   3268 H HE3  . TRP A 1 205 ? -3.880  -15.446 -19.664 1.000 7.412  0 220  TRP A HE3  1 c 
ATOM   3269 H HZ2  . TRP A 1 205 ? -8.150  -14.604 -17.864 1.000 7.190  0 220  TRP A HZ2  1 c 
ATOM   3270 H HZ3  . TRP A 1 205 ? -4.244  -15.538 -17.386 1.000 7.840  0 220  TRP A HZ3  1 c 
ATOM   3271 H HH2  . TRP A 1 205 ? -6.341  -15.126 -16.491 1.000 7.607  0 220  TRP A HH2  1 c 
ATOM   3272 N N    . LEU A 1 206 ? -2.858  -12.662 -21.663 1.000 6.934  0 221  LEU A N    1 ? 
ATOM   3273 C CA   . LEU A 1 206 ? -2.601  -11.676 -20.624 1.000 7.816  0 221  LEU A CA   1 ? 
ATOM   3274 C C    . LEU A 1 206 ? -2.917  -10.261 -21.073 1.000 7.977  0 221  LEU A C    1 ? 
ATOM   3275 O O    . LEU A 1 206 ? -3.364  -9.438  -20.250 1.000 7.564  0 221  LEU A O    1 ? 
ATOM   3276 C CB   . LEU A 1 206 ? -1.177  -11.802 -20.128 1.000 9.677  0 221  LEU A CB   1 ? 
ATOM   3277 C CG   . LEU A 1 206 ? -0.919  -11.042 -18.824 1.000 12.290 0 221  LEU A CG   1 ? 
ATOM   3278 C CD1  . LEU A 1 206 ? -1.832  -11.489 -17.723 1.000 13.553 0 221  LEU A CD1  1 ? 
ATOM   3279 C CD2  . LEU A 1 206 ? 0.562   -11.182 -18.452 1.000 14.555 0 221  LEU A CD2  1 ? 
ATOM   3280 H H    . LEU A 1 206 ? -2.195  -13.245 -21.898 1.000 7.182  0 221  LEU A H    1 c 
ATOM   3281 H HA   . LEU A 1 206 ? -3.211  -11.885 -19.873 1.000 8.025  0 221  LEU A HA   1 c 
ATOM   3282 H HB2  . LEU A 1 206 ? -0.981  -12.755 -19.980 1.000 9.698  0 221  LEU A HB2  1 c 
ATOM   3283 H HB3  . LEU A 1 206 ? -0.572  -11.454 -20.823 1.000 9.710  0 221  LEU A HB3  1 c 
ATOM   3284 H HG   . LEU A 1 206 ? -1.096  -10.080 -18.990 1.000 12.302 0 221  LEU A HG   1 c 
ATOM   3285 H HD11 . LEU A 1 206 ? -2.689  -11.038 -17.806 1.000 13.060 0 221  LEU A HD11 1 c 
ATOM   3286 H HD12 . LEU A 1 206 ? -1.435  -11.271 -16.863 1.000 13.079 0 221  LEU A HD12 1 c 
ATOM   3287 H HD13 . LEU A 1 206 ? -1.966  -12.450 -17.781 1.000 13.105 0 221  LEU A HD13 1 c 
ATOM   3288 H HD21 . LEU A 1 206 ? 1.113   -10.818 -19.165 1.000 13.819 0 221  LEU A HD21 1 c 
ATOM   3289 H HD22 . LEU A 1 206 ? 0.777   -12.121 -18.326 1.000 13.831 0 221  LEU A HD22 1 c 
ATOM   3290 H HD23 . LEU A 1 206 ? 0.738   -10.697 -17.628 1.000 13.836 0 221  LEU A HD23 1 c 
ATOM   3291 N N    . TYR A 1 207 ? -2.641  -9.916  -22.344 1.000 7.432  0 222  TYR A N    1 ? 
ATOM   3292 C CA   . TYR A 1 207 ? -2.879  -8.556  -22.832 1.000 7.186  0 222  TYR A CA   1 ? 
ATOM   3293 C C    . TYR A 1 207 ? -4.063  -8.444  -23.785 1.000 6.898  0 222  TYR A C    1 ? 
ATOM   3294 O O    . TYR A 1 207 ? -4.309  -7.386  -24.341 1.000 7.730  0 222  TYR A O    1 ? 
ATOM   3295 C CB   . TYR A 1 207 ? -1.583  -7.914  -23.389 1.000 7.526  0 222  TYR A CB   1 ? 
ATOM   3296 C CG   . TYR A 1 207 ? -0.549  -7.797  -22.286 1.000 7.567  0 222  TYR A CG   1 ? 
ATOM   3297 C CD1  . TYR A 1 207 ? -0.545  -6.703  -21.420 1.000 8.432  0 222  TYR A CD1  1 ? 
ATOM   3298 C CD2  . TYR A 1 207 ? 0.414   -8.759  -22.114 1.000 8.173  0 222  TYR A CD2  1 ? 
ATOM   3299 C CE1  . TYR A 1 207 ? 0.363   -6.609  -20.390 1.000 8.695  0 222  TYR A CE1  1 ? 
ATOM   3300 C CE2  . TYR A 1 207 ? 1.346   -8.678  -21.084 1.000 9.048  0 222  TYR A CE2  1 ? 
ATOM   3301 C CZ   . TYR A 1 207 ? 1.318   -7.583  -20.239 1.000 9.038  0 222  TYR A CZ   1 ? 
ATOM   3302 O OH   . TYR A 1 207 ? 2.265   -7.549  -19.220 1.000 10.461 0 222  TYR A OH   1 ? 
ATOM   3303 H H    . TYR A 1 207 ? -2.285  -10.535 -22.915 1.000 7.493  0 222  TYR A H    1 c 
ATOM   3304 H HA   . TYR A 1 207 ? -3.124  -8.016  -22.035 1.000 7.247  0 222  TYR A HA   1 c 
ATOM   3305 H HB2  . TYR A 1 207 ? -1.230  -8.476  -24.114 1.000 7.458  0 222  TYR A HB2  1 c 
ATOM   3306 H HB3  . TYR A 1 207 ? -1.790  -7.020  -23.743 1.000 7.460  0 222  TYR A HB3  1 c 
ATOM   3307 H HD1  . TYR A 1 207 ? -1.205  -6.034  -21.515 1.000 8.294  0 222  TYR A HD1  1 c 
ATOM   3308 H HD2  . TYR A 1 207 ? 0.426   -9.509  -22.687 1.000 8.229  0 222  TYR A HD2  1 c 
ATOM   3309 H HE1  . TYR A 1 207 ? 0.350   -5.867  -19.811 1.000 8.710  0 222  TYR A HE1  1 c 
ATOM   3310 H HE2  . TYR A 1 207 ? 1.997   -9.350  -20.973 1.000 8.830  0 222  TYR A HE2  1 c 
ATOM   3311 H HH   . TYR A 1 207 ? 1.965   -7.957  -18.527 0.000 10.470 0 222  TYR A HH   1 c 
ATOM   3312 N N    . LEU A 1 208 ? -4.818  -9.546  -23.942 1.000 6.746  0 223  LEU A N    1 ? 
ATOM   3313 C CA   . LEU A 1 208 ? -6.111  -9.552  -24.608 1.000 7.455  0 223  LEU A CA   1 ? 
ATOM   3314 C C    . LEU A 1 208 ? -6.063  -9.013  -26.047 1.000 7.335  0 223  LEU A C    1 ? 
ATOM   3315 O O    . LEU A 1 208 ? -7.041  -8.493  -26.561 1.000 7.197  0 223  LEU A O    1 ? 
ATOM   3316 C CB   . LEU A 1 208 ? -7.189  -8.851  -23.774 1.000 7.285  0 223  LEU A CB   1 ? 
ATOM   3317 C CG   . LEU A 1 208 ? -7.497  -9.460  -22.414 1.000 6.995  0 223  LEU A CG   1 ? 
ATOM   3318 C CD1  . LEU A 1 208 ? -8.407  -8.549  -21.614 1.000 7.036  0 223  LEU A CD1  1 ? 
ATOM   3319 C CD2  . LEU A 1 208 ? -8.112  -10.841 -22.532 1.000 7.064  0 223  LEU A CD2  1 ? 
ATOM   3320 H H    . LEU A 1 208 ? -4.502  -10.340 -23.619 1.000 6.948  0 223  LEU A H    1 c 
ATOM   3321 H HA   . LEU A 1 208 ? -6.372  -10.502 -24.686 1.000 7.268  0 223  LEU A HA   1 c 
ATOM   3322 H HB2  . LEU A 1 208 ? -6.911  -7.916  -23.638 1.000 7.253  0 223  LEU A HB2  1 c 
ATOM   3323 H HB3  . LEU A 1 208 ? -8.022  -8.836  -24.299 1.000 7.255  0 223  LEU A HB3  1 c 
ATOM   3324 H HG   . LEU A 1 208 ? -6.643  -9.550  -21.917 1.000 7.067  0 223  LEU A HG   1 c 
ATOM   3325 H HD11 . LEU A 1 208 ? -7.970  -7.692  -21.477 1.000 7.032  0 223  LEU A HD11 1 c 
ATOM   3326 H HD12 . LEU A 1 208 ? -8.598  -8.956  -20.752 1.000 7.026  0 223  LEU A HD12 1 c 
ATOM   3327 H HD13 . LEU A 1 208 ? -9.239  -8.414  -22.098 1.000 7.026  0 223  LEU A HD13 1 c 
ATOM   3328 H HD21 . LEU A 1 208 ? -7.462  -11.456 -22.910 1.000 7.049  0 223  LEU A HD21 1 c 
ATOM   3329 H HD22 . LEU A 1 208 ? -8.893  -10.800 -23.110 1.000 7.045  0 223  LEU A HD22 1 c 
ATOM   3330 H HD23 . LEU A 1 208 ? -8.378  -11.154 -21.652 1.000 7.045  0 223  LEU A HD23 1 c 
ATOM   3331 N N    . LYS A 1 209 ? -4.908  -9.181  -26.722 1.000 7.716  0 224  LYS A N    1 ? 
ATOM   3332 C CA   . LYS A 1 209 ? -4.738  -8.699  -28.093 1.000 8.325  0 224  LYS A CA   1 ? 
ATOM   3333 C C    . LYS A 1 209 ? -4.997  -7.176  -28.191 1.000 7.738  0 224  LYS A C    1 ? 
ATOM   3334 O O    . LYS A 1 209 ? -5.289  -6.652  -29.292 1.000 9.461  0 224  LYS A O    1 ? 
ATOM   3335 C CB   . LYS A 1 209 ? -5.581  -9.460  -29.119 1.000 8.982  0 224  LYS A CB   1 ? 
ATOM   3336 C CG   . LYS A 1 209 ? -5.044  -10.866 -29.365 1.000 9.764  0 224  LYS A CG   1 ? 
ATOM   3337 C CD   . LYS A 1 209 ? -5.912  -11.729 -30.285 1.000 11.002 0 224  LYS A CD   1 ? 
ATOM   3338 C CE   . LYS A 1 209 ? -7.140  -12.304 -29.623 1.000 12.288 0 224  LYS A CE   1 ? 
ATOM   3339 N NZ   . LYS A 1 209 ? -8.121  -12.770 -30.652 1.000 14.861 0 224  LYS A NZ   1 ? 
ATOM   3340 H H    . LYS A 1 209 ? -4.213  -9.619  -26.323 1.000 7.740  0 224  LYS A H    1 c 
ATOM   3341 H HA   . LYS A 1 209 ? -3.790  -8.851  -28.340 1.000 8.218  0 224  LYS A HA   1 c 
ATOM   3342 H HB2  . LYS A 1 209 ? -6.507  -9.525  -28.802 1.000 8.998  0 224  LYS A HB2  1 c 
ATOM   3343 H HB3  . LYS A 1 209 ? -5.583  -8.972  -29.969 1.000 8.995  0 224  LYS A HB3  1 c 
ATOM   3344 H HG2  . LYS A 1 209 ? -4.146  -10.791 -29.756 1.000 9.842  0 224  LYS A HG2  1 c 
ATOM   3345 H HG3  . LYS A 1 209 ? -4.953  -11.319 -28.498 1.000 9.842  0 224  LYS A HG3  1 c 
ATOM   3346 H HD2  . LYS A 1 209 ? -6.192  -11.184 -31.052 1.000 11.002 0 224  LYS A HD2  1 c 
ATOM   3347 H HD3  . LYS A 1 209 ? -5.364  -12.466 -30.631 1.000 10.988 0 224  LYS A HD3  1 c 
ATOM   3348 H HE2  . LYS A 1 209 ? -6.886  -13.059 -29.062 1.000 12.473 0 224  LYS A HE2  1 c 
ATOM   3349 H HE3  . LYS A 1 209 ? -7.551  -11.626 -29.059 1.000 12.514 0 224  LYS A HE3  1 c 
ATOM   3350 H HZ1  . LYS A 1 209 ? -7.713  -13.366 -31.200 1.000 14.006 0 224  LYS A HZ1  1 c 
ATOM   3351 H HZ2  . LYS A 1 209 ? -8.407  -12.071 -31.151 1.000 14.006 0 224  LYS A HZ2  1 c 
ATOM   3352 H HZ3  . LYS A 1 209 ? -8.822  -13.179 -30.253 1.000 14.023 0 224  LYS A HZ3  1 c 
ATOM   3353 N N    . GLY A 1 210 ? -4.858  -6.463  -27.072 1.000 7.500  0 225  GLY A N    1 ? 
ATOM   3354 C CA   . GLY A 1 210 ? -5.141  -5.033  -27.046 1.000 8.334  0 225  GLY A CA   1 ? 
ATOM   3355 C C    . GLY A 1 210 ? -6.561  -4.687  -26.637 1.000 8.710  0 225  GLY A C    1 ? 
ATOM   3356 O O    . GLY A 1 210 ? -6.872  -3.498  -26.457 1.000 9.757  0 225  GLY A O    1 ? 
ATOM   3357 H H    . GLY A 1 210 ? -4.557  -6.865  -26.310 1.000 7.739  0 225  GLY A H    1 c 
ATOM   3358 H HA2  . GLY A 1 210 ? -4.515  -4.603  -26.419 1.000 8.222  0 225  GLY A HA2  1 c 
ATOM   3359 H HA3  . GLY A 1 210 ? -4.965  -4.658  -27.938 1.000 8.216  0 225  GLY A HA3  1 c 
ATOM   3360 N N    . SER A 1 211 ? -7.423  -5.681  -26.547 1.000 8.307  0 226  SER A N    1 ? 
ATOM   3361 C CA   . SER A 1 211 ? -8.818  -5.459  -26.161 1.000 8.159  0 226  SER A CA   1 ? 
ATOM   3362 C C    . SER A 1 211 ? -9.037  -5.547  -24.638 1.000 8.417  0 226  SER A C    1 ? 
ATOM   3363 O O    . SER A 1 211 ? -10.018 -6.114  -24.135 1.000 9.104  0 226  SER A O    1 ? 
ATOM   3364 C CB   . SER A 1 211 ? -9.703  -6.454  -26.866 1.000 9.204  0 226  SER A CB   1 ? 
ATOM   3365 O OG   . SER A 1 211 ? -9.646  -6.232  -28.270 1.000 11.450 0 226  SER A OG   1 ? 
ATOM   3366 H H    . SER A 1 211 ? -7.152  -6.534  -26.729 1.000 8.356  0 226  SER A H    1 c 
ATOM   3367 H HA   . SER A 1 211 ? -9.079  -4.550  -26.457 1.000 8.430  0 226  SER A HA   1 c 
ATOM   3368 H HB2  . SER A 1 211 ? -9.404  -7.360  -26.664 1.000 9.421  0 226  SER A HB2  1 c 
ATOM   3369 H HB3  . SER A 1 211 ? -10.623 -6.352  -26.557 1.000 9.426  0 226  SER A HB3  1 c 
ATOM   3370 H HG   . SER A 1 211 ? -10.147 -6.796  -28.652 0.000 11.460 0 226  SER A HG   1 c 
ATOM   3371 N N    . TYR A 1 212 ? -8.141  -4.879  -23.905 1.000 8.567  0 227  TYR A N    1 ? 
ATOM   3372 C CA   . TYR A 1 212 ? -8.218  -4.716  -22.466 1.000 7.876  0 227  TYR A CA   1 ? 
ATOM   3373 C C    . TYR A 1 212 ? -9.047  -3.493  -22.099 1.000 7.734  0 227  TYR A C    1 ? 
ATOM   3374 O O    . TYR A 1 212 ? -9.419  -2.671  -22.953 1.000 8.837  0 227  TYR A O    1 ? 
ATOM   3375 C CB   . TYR A 1 212 ? -6.809  -4.685  -21.880 1.000 8.076  0 227  TYR A CB   1 ? 
ATOM   3376 C CG   . TYR A 1 212 ? -5.895  -3.656  -22.512 1.000 8.283  0 227  TYR A CG   1 ? 
ATOM   3377 C CD1  . TYR A 1 212 ? -5.966  -2.318  -22.126 1.000 9.818  0 227  TYR A CD1  1 ? 
ATOM   3378 C CD2  . TYR A 1 212 ? -4.997  -4.000  -23.491 1.000 8.309  0 227  TYR A CD2  1 ? 
ATOM   3379 C CE1  . TYR A 1 212 ? -5.126  -1.384  -22.686 1.000 9.969  0 227  TYR A CE1  1 ? 
ATOM   3380 C CE2  . TYR A 1 212 ? -4.163  -3.055  -24.062 1.000 9.521  0 227  TYR A CE2  1 ? 
ATOM   3381 C CZ   . TYR A 1 212 ? -4.245  -1.747  -23.668 1.000 10.076 0 227  TYR A CZ   1 ? 
ATOM   3382 O OH   . TYR A 1 212 ? -3.410  -0.797  -24.248 1.000 12.752 0 227  TYR A OH   1 ? 
ATOM   3383 H H    . TYR A 1 212 ? -7.446  -4.480  -24.341 1.000 8.367  0 227  TYR A H    1 c 
ATOM   3384 H HA   . TYR A 1 212 ? -8.679  -5.514  -22.096 1.000 8.015  0 227  TYR A HA   1 c 
ATOM   3385 H HB2  . TYR A 1 212 ? -6.876  -4.500  -20.918 1.000 8.074  0 227  TYR A HB2  1 c 
ATOM   3386 H HB3  . TYR A 1 212 ? -6.408  -5.576  -21.988 1.000 8.077  0 227  TYR A HB3  1 c 
ATOM   3387 H HD1  . TYR A 1 212 ? -6.572  -2.057  -21.451 1.000 9.461  0 227  TYR A HD1  1 c 
ATOM   3388 H HD2  . TYR A 1 212 ? -4.938  -4.899  -23.772 1.000 8.594  0 227  TYR A HD2  1 c 
ATOM   3389 H HE1  . TYR A 1 212 ? -5.184  -0.482  -22.419 1.000 9.947  0 227  TYR A HE1  1 c 
ATOM   3390 H HE2  . TYR A 1 212 ? -3.552  -3.306  -24.733 1.000 9.351  0 227  TYR A HE2  1 c 
ATOM   3391 H HH   . TYR A 1 212 ? -2.673  -0.750  -23.811 0.000 12.750 0 227  TYR A HH   1 c 
ATOM   3392 N N    . MET A 1 213 ? -9.428  -3.423  -20.815 1.000 7.593  0 228  MET A N    1 ? 
ATOM   3393 C CA   . MET A 1 213 ? -10.238 -2.335  -20.305 1.000 7.783  0 228  MET A CA   1 ? 
ATOM   3394 C C    . MET A 1 213 ? -9.379  -1.106  -20.074 1.000 8.018  0 228  MET A C    1 ? 
ATOM   3395 O O    . MET A 1 213 ? -8.341  -1.204  -19.456 1.000 10.026 0 228  MET A O    1 ? 
ATOM   3396 C CB   . MET A 1 213 ? -10.896 -2.717  -18.987 1.000 8.102  0 228  MET A CB   1 ? 
ATOM   3397 C CG   . MET A 1 213 ? -11.796 -3.900  -19.093 1.000 8.388  0 228  MET A CG   1 ? 
ATOM   3398 S SD   . MET A 1 213 ? -12.382 -4.462  -17.477 1.000 12.359 0 228  MET A SD   1 ? 
ATOM   3399 C CE   . MET A 1 213 ? -13.107 -2.919  -16.881 1.000 14.641 0 228  MET A CE   1 ? 
ATOM   3400 H H    . MET A 1 213 ? -9.164  -4.080  -20.238 1.000 7.689  0 228  MET A H    1 c 
ATOM   3401 H HA   . MET A 1 213 ? -10.937 -2.122  -20.974 1.000 7.870  0 228  MET A HA   1 c 
ATOM   3402 H HB2  . MET A 1 213 ? -10.195 -2.906  -18.328 1.000 8.101  0 228  MET A HB2  1 c 
ATOM   3403 H HB3  . MET A 1 213 ? -11.412 -1.949  -18.665 1.000 8.154  0 228  MET A HB3  1 c 
ATOM   3404 H HG2  . MET A 1 213 ? -12.568 -3.671  -19.646 1.000 8.949  0 228  MET A HG2  1 c 
ATOM   3405 H HG3  . MET A 1 213 ? -11.321 -4.635  -19.528 1.000 8.938  0 228  MET A HG3  1 c 
ATOM   3406 H HE1  . MET A 1 213 ? -13.531 -3.073  -16.018 1.000 13.904 0 228  MET A HE1  1 c 
ATOM   3407 H HE2  . MET A 1 213 ? -12.408 -2.249  -16.775 1.000 13.899 0 228  MET A HE2  1 c 
ATOM   3408 H HE3  . MET A 1 213 ? -13.771 -2.603  -17.521 1.000 13.983 0 228  MET A HE3  1 c 
ATOM   3409 N N    . ARG A 1 214 ? -9.813  0.040   -20.589 1.000 9.217  0 229  ARG A N    1 ? 
ATOM   3410 C CA   . ARG A 1 214 ? -9.215  1.341   -20.327 1.000 8.877  0 229  ARG A CA   1 ? 
ATOM   3411 C C    . ARG A 1 214 ? -10.227 2.102   -19.473 1.000 9.165  0 229  ARG A C    1 ? 
ATOM   3412 O O    . ARG A 1 214 ? -11.233 2.611   -19.968 1.000 10.155 0 229  ARG A O    1 ? 
ATOM   3413 C CB   . ARG A 1 214 ? -8.904  2.053   -21.669 1.000 11.162 0 229  ARG A CB   1 ? 
ATOM   3414 C CG   . ARG A 1 214 ? -7.863  1.355   -22.538 1.000 13.257 0 229  ARG A CG   1 ? 
ATOM   3415 C CD   . ARG A 1 214 ? -8.019  1.659   -24.032 1.000 17.589 0 229  ARG A CD   1 ? 
ATOM   3416 N NE   . ARG A 1 214 ? -7.030  0.984   -24.890 1.000 18.435 0 229  ARG A NE   1 ? 
ATOM   3417 C CZ   . ARG A 1 214 ? -7.096  -0.280  -25.378 1.000 19.166 0 229  ARG A CZ   1 ? 
ATOM   3418 N NH1  . ARG A 1 214 ? -7.968  -1.156  -24.934 1.000 20.222 0 229  ARG A NH1  1 ? 
ATOM   3419 N NH2  . ARG A 1 214 ? -6.206  -0.690  -26.264 1.000 17.499 0 229  ARG A NH2  1 ? 
ATOM   3420 H H    . ARG A 1 214 ? -10.536 0.011   -21.148 1.000 8.823  0 229  ARG A H    1 c 
ATOM   3421 H HA   . ARG A 1 214 ? -8.377  1.216   -19.813 1.000 9.358  0 229  ARG A HA   1 c 
ATOM   3422 H HB2  . ARG A 1 214 ? -9.738  2.131   -22.181 1.000 11.053 0 229  ARG A HB2  1 c 
ATOM   3423 H HB3  . ARG A 1 214 ? -8.591  2.962   -21.474 1.000 11.033 0 229  ARG A HB3  1 c 
ATOM   3424 H HG2  . ARG A 1 214 ? -6.967  1.635   -22.250 1.000 13.598 0 229  ARG A HG2  1 c 
ATOM   3425 H HG3  . ARG A 1 214 ? -7.929  0.385   -22.402 1.000 13.603 0 229  ARG A HG3  1 c 
ATOM   3426 H HD2  . ARG A 1 214 ? -8.918  1.391   -24.312 1.000 16.683 0 229  ARG A HD2  1 c 
ATOM   3427 H HD3  . ARG A 1 214 ? -7.946  2.627   -24.163 1.000 16.683 0 229  ARG A HD3  1 c 
ATOM   3428 H HE   . ARG A 1 214 ? -6.324  1.444   -25.108 1.000 18.394 0 229  ARG A HE   1 c 
ATOM   3429 H HH11 . ARG A 1 214 ? -8.075  -1.926  -25.357 1.000 19.836 0 229  ARG A HH11 1 c 
ATOM   3430 H HH12 . ARG A 1 214 ? -8.447  -0.979  -24.214 1.000 19.804 0 229  ARG A HH12 1 c 
ATOM   3431 H HH21 . ARG A 1 214 ? -6.375  -1.402  -26.761 1.000 18.029 0 229  ARG A HH21 1 c 
ATOM   3432 H HH22 . ARG A 1 214 ? -5.435  -0.263  -26.341 1.000 18.010 0 229  ARG A HH22 1 c 
ATOM   3433 N N    . CYS A 1 215 ? -9.979  2.139   -18.176 1.000 8.683  0 230  CYS A N    1 ? 
ATOM   3434 C CA   . CYS A 1 215 ? -10.954 2.705   -17.248 1.000 8.608  0 230  CYS A CA   1 ? 
ATOM   3435 C C    . CYS A 1 215 ? -11.014 4.228   -17.320 1.000 8.639  0 230  CYS A C    1 ? 
ATOM   3436 O O    . CYS A 1 215 ? -9.997  4.872   -17.507 1.000 10.278 0 230  CYS A O    1 ? 
ATOM   3437 C CB   . CYS A 1 215 ? -10.602 2.352   -15.818 1.000 8.492  0 230  CYS A CB   1 ? 
ATOM   3438 S SG   . CYS A 1 215 ? -10.726 0.583   -15.424 1.000 9.918  0 230  CYS A SG   1 ? 
ATOM   3439 H H    . CYS A 1 215 ? -9.191  1.811   -17.849 1.000 8.782  0 230  CYS A H    1 c 
ATOM   3440 H HA   . CYS A 1 215 ? -11.846 2.336   -17.468 1.000 8.637  0 230  CYS A HA   1 c 
ATOM   3441 H HB2  . CYS A 1 215 ? -9.684  2.648   -15.631 1.000 8.768  0 230  CYS A HB2  1 c 
ATOM   3442 H HB3  . CYS A 1 215 ? -11.203 2.842   -15.215 1.000 8.775  0 230  CYS A HB3  1 c 
ATOM   3443 H HG   . CYS A 1 215 ? -10.392 0.655   -14.261 0.000 9.920  0 230  CYS A HG   1 c 
ATOM   3444 N N    . ASP A 1 216 ? -12.231 4.764   -17.187 1.000 9.058  0 231  ASP A N    1 ? 
ATOM   3445 C CA   . ASP A 1 216 ? -12.408 6.140   -16.717 1.000 9.506  0 231  ASP A CA   1 ? 
ATOM   3446 C C    . ASP A 1 216 ? -12.478 6.112   -15.183 1.000 9.747  0 231  ASP A C    1 ? 
ATOM   3447 O O    . ASP A 1 216 ? -12.373 5.053   -14.535 1.000 9.405  0 231  ASP A O    1 ? 
ATOM   3448 C CB   . ASP A 1 216 ? -13.622 6.746   -17.421 1.000 10.890 0 231  ASP A CB   1 ? 
ATOM   3449 C CG   . ASP A 1 216 ? -14.965 6.189   -17.021 1.000 15.238 0 231  ASP A CG   1 ? 
ATOM   3450 O OD1  . ASP A 1 216 ? -15.058 5.312   -16.189 1.000 13.476 0 231  ASP A OD1  1 ? 
ATOM   3451 O OD2  . ASP A 1 216 ? -15.975 6.653   -17.589 1.000 19.090 0 231  ASP A OD2  1 ? 
ATOM   3452 H H    . ASP A 1 216 ? -12.970 4.267   -17.393 1.000 9.084  0 231  ASP A H    1 c 
ATOM   3453 H HA   . ASP A 1 216 ? -11.620 6.664   -16.984 1.000 9.699  0 231  ASP A HA   1 c 
ATOM   3454 H HB2  . ASP A 1 216 ? -13.631 7.711   -17.249 1.000 11.441 0 231  ASP A HB2  1 c 
ATOM   3455 H HB3  . ASP A 1 216 ? -13.517 6.617   -18.387 1.000 11.427 0 231  ASP A HB3  1 c 
ATOM   3456 N N    . ARG A 1 217 ? -12.690 7.282   -14.548 1.000 9.403  0 232  ARG A N    1 ? 
ATOM   3457 C CA   . ARG A 1 217 ? -12.725 7.322   -13.102 1.000 10.157 0 232  ARG A CA   1 ? 
ATOM   3458 C C    . ARG A 1 217 ? -13.873 6.505   -12.528 1.000 9.927  0 232  ARG A C    1 ? 
ATOM   3459 O O    . ARG A 1 217 ? -13.715 5.918   -11.444 1.000 10.578 0 232  ARG A O    1 ? 
ATOM   3460 C CB   . ARG A 1 217 ? -12.781 8.775   -12.600 1.000 11.649 0 232  ARG A CB   1 ? 
ATOM   3461 C CG   . ARG A 1 217 ? -11.479 9.551   -12.722 1.000 13.890 0 232  ARG A CG   1 ? 
ATOM   3462 C CD   . ARG A 1 217 ? -10.483 9.287   -11.636 1.000 14.283 0 232  ARG A CD   1 ? 
ATOM   3463 N NE   . ARG A 1 217 ? -9.247  10.031  -11.837 1.000 14.721 0 232  ARG A NE   1 ? 
ATOM   3464 C CZ   . ARG A 1 217 ? -8.184  9.604   -12.358 1.000 16.407 0 232  ARG A CZ   1 ? 
ATOM   3465 N NH1  . ARG A 1 217 ? -8.026  8.336   -12.665 1.000 17.207 0 232  ARG A NH1  1 ? 
ATOM   3466 N NH2  . ARG A 1 217 ? -7.242  10.485  -12.664 1.000 18.032 0 232  ARG A NH2  1 ? 
ATOM   3467 H H    . ARG A 1 217 ? -12.811 8.052   -15.025 1.000 9.695  0 232  ARG A H    1 c 
ATOM   3468 H HA   . ARG A 1 217 ? -11.881 6.931   -12.770 1.000 10.205 0 232  ARG A HA   1 c 
ATOM   3469 H HB2  . ARG A 1 217 ? -13.476 9.251   -13.103 1.000 11.815 0 232  ARG A HB2  1 c 
ATOM   3470 H HB3  . ARG A 1 217 ? -13.051 8.768   -11.657 1.000 11.760 0 232  ARG A HB3  1 c 
ATOM   3471 H HG2  . ARG A 1 217 ? -11.066 9.336   -13.584 1.000 13.425 0 232  ARG A HG2  1 c 
ATOM   3472 H HG3  . ARG A 1 217 ? -11.685 10.511  -12.732 1.000 13.430 0 232  ARG A HG3  1 c 
ATOM   3473 H HD2  . ARG A 1 217 ? -10.876 9.550   -10.779 1.000 14.282 0 232  ARG A HD2  1 c 
ATOM   3474 H HD3  . ARG A 1 217 ? -10.289 8.332   -11.592 1.000 14.295 0 232  ARG A HD3  1 c 
ATOM   3475 H HE   . ARG A 1 217 ? -9.241  10.858  -11.565 1.000 15.037 0 232  ARG A HE   1 c 
ATOM   3476 H HH11 . ARG A 1 217 ? -7.233  7.959   -12.545 1.000 16.758 0 232  ARG A HH11 1 c 
ATOM   3477 H HH12 . ARG A 1 217 ? -8.698  7.868   -13.001 1.000 16.752 0 232  ARG A HH12 1 c 
ATOM   3478 H HH21 . ARG A 1 217 ? -6.390  10.247  -12.617 1.000 17.496 0 232  ARG A HH21 1 c 
ATOM   3479 H HH22 . ARG A 1 217 ? -7.466  11.305  -12.915 1.000 17.458 0 232  ARG A HH22 1 c 
ATOM   3480 N N    . LYS A 1 218 ? -15.003 6.464   -13.209 1.000 9.941  0 233  LYS A N    1 ? 
ATOM   3481 C CA   . LYS A 1 218 ? -16.139 5.722   -12.693 1.000 10.952 0 233  LYS A CA   1 ? 
ATOM   3482 C C    . LYS A 1 218 ? -15.857 4.225   -12.708 1.000 9.709  0 233  LYS A C    1 ? 
ATOM   3483 O O    . LYS A 1 218 ? -16.293 3.496   -11.826 1.000 10.270 0 233  LYS A O    1 ? 
ATOM   3484 C CB   . LYS A 1 218 ? -17.386 6.072   -13.520 1.000 13.766 0 233  LYS A CB   1 ? 
ATOM   3485 C CG   . LYS A 1 218 ? -17.624 7.520   -13.855 1.000 21.196 0 233  LYS A CG   1 ? 
ATOM   3486 C CD   . LYS A 1 218 ? -17.956 8.283   -12.592 1.000 24.229 0 233  LYS A CD   1 ? 
ATOM   3487 C CE   . LYS A 1 218 ? -18.609 9.616   -12.922 1.000 30.282 0 233  LYS A CE   1 ? 
ATOM   3488 N NZ   . LYS A 1 218 ? -17.833 10.468  -13.811 1.000 36.753 0 233  LYS A NZ   1 ? 
ATOM   3489 H H    . LYS A 1 218 ? -15.067 6.883   -14.018 1.000 10.292 0 233  LYS A H    1 c 
ATOM   3490 H HA   . LYS A 1 218 ? -16.296 6.003   -11.755 1.000 10.953 0 233  LYS A HA   1 c 
ATOM   3491 H HB2  . LYS A 1 218 ? -17.339 5.573   -14.363 1.000 14.457 0 233  LYS A HB2  1 c 
ATOM   3492 H HB3  . LYS A 1 218 ? -18.171 5.742   -13.033 1.000 14.550 0 233  LYS A HB3  1 c 
ATOM   3493 H HG2  . LYS A 1 218 ? -16.821 7.900   -14.271 1.000 19.623 0 233  LYS A HG2  1 c 
ATOM   3494 H HG3  . LYS A 1 218 ? -18.369 7.589   -14.490 1.000 19.750 0 233  LYS A HG3  1 c 
ATOM   3495 H HD2  . LYS A 1 218 ? -18.569 7.752   -12.038 1.000 24.545 0 233  LYS A HD2  1 c 
ATOM   3496 H HD3  . LYS A 1 218 ? -17.133 8.443   -12.081 1.000 24.690 0 233  LYS A HD3  1 c 
ATOM   3497 H HE2  . LYS A 1 218 ? -19.474 9.447   -13.336 1.000 30.074 0 233  LYS A HE2  1 c 
ATOM   3498 H HE3  . LYS A 1 218 ? -18.770 10.100  -12.093 1.000 30.070 0 233  LYS A HE3  1 c 
ATOM   3499 H HZ1  . LYS A 1 218 ? -17.925 10.187  -14.668 1.000 34.520 0 233  LYS A HZ1  1 c 
ATOM   3500 H HZ2  . LYS A 1 218 ? -16.958 10.438  -13.579 1.000 34.531 0 233  LYS A HZ2  1 c 
ATOM   3501 H HZ3  . LYS A 1 218 ? -18.128 11.323  -13.747 1.000 34.586 0 233  LYS A HZ3  1 c 
ATOM   3502 N N    . MET A 1 219 ? -15.192 3.720   -13.772 1.000 8.566  0 234  MET A N    1 ? 
ATOM   3503 C CA   . MET A 1 219 ? -14.819 2.313   -13.845 1.000 8.534  0 234  MET A CA   1 ? 
ATOM   3504 C C    . MET A 1 219 ? -13.782 1.985   -12.785 1.000 7.874  0 234  MET A C    1 ? 
ATOM   3505 O O    . MET A 1 219 ? -13.738 0.850   -12.325 1.000 8.237  0 234  MET A O    1 ? 
ATOM   3506 C CB   . MET A 1 219 ? -14.281 1.931   -15.220 1.000 9.366  0 234  MET A CB   1 ? 
ATOM   3507 C CG   . MET A 1 219 ? -15.350 2.026   -16.320 1.000 9.891  0 234  MET A CG   1 ? 
ATOM   3508 S SD   . MET A 1 219 ? -14.723 2.027   -18.005 1.000 12.855 0 234  MET A SD   1 ? 
ATOM   3509 C CE   . MET A 1 219 ? -14.108 0.373   -18.068 1.000 15.606 0 234  MET A CE   1 ? 
ATOM   3510 H H    . MET A 1 219 ? -14.975 4.270   -14.468 1.000 8.842  0 234  MET A H    1 c 
ATOM   3511 H HA   . MET A 1 219 ? -15.629 1.774   -13.657 1.000 8.572  0 234  MET A HA   1 c 
ATOM   3512 H HB2  . MET A 1 219 ? -13.534 2.525   -15.445 1.000 9.283  0 234  MET A HB2  1 c 
ATOM   3513 H HB3  . MET A 1 219 ? -13.938 1.012   -15.183 1.000 9.302  0 234  MET A HB3  1 c 
ATOM   3514 H HG2  . MET A 1 219 ? -15.965 1.271   -16.225 1.000 10.286 0 234  MET A HG2  1 c 
ATOM   3515 H HG3  . MET A 1 219 ? -15.868 2.843   -16.187 1.000 10.280 0 234  MET A HG3  1 c 
ATOM   3516 H HE1  . MET A 1 219 ? -13.742 0.197   -18.954 1.000 14.833 0 234  MET A HE1  1 c 
ATOM   3517 H HE2  . MET A 1 219 ? -13.409 0.261   -17.398 1.000 14.769 0 234  MET A HE2  1 c 
ATOM   3518 H HE3  . MET A 1 219 ? -14.836 -0.251  -17.887 1.000 14.833 0 234  MET A HE3  1 c 
ATOM   3519 N N    . GLU A 1 220 ? -12.907 2.942   -12.425 1.000 7.897  0 235  GLU A N    1 ? 
ATOM   3520 C CA   . GLU A 1 220 ? -11.973 2.737   -11.321 1.000 7.208  0 235  GLU A CA   1 ? 
ATOM   3521 C C    . GLU A 1 220 ? -12.708 2.559   -9.995  1.000 7.517  0 235  GLU A C    1 ? 
ATOM   3522 O O    . GLU A 1 220 ? -12.275 1.757   -9.155  1.000 7.781  0 235  GLU A O    1 ? 
ATOM   3523 C CB   . GLU A 1 220 ? -10.972 3.904   -11.282 1.000 7.632  0 235  GLU A CB   1 ? 
ATOM   3524 C CG   . GLU A 1 220 ? -10.004 3.798   -12.470 1.000 8.322  0 235  GLU A CG   1 ? 
ATOM   3525 C CD   . GLU A 1 220 ? -9.414  5.113   -12.913 1.000 9.636  0 235  GLU A CD   1 ? 
ATOM   3526 O OE1  . GLU A 1 220 ? -9.687  6.176   -12.356 1.000 9.332  0 235  GLU A OE1  1 ? 
ATOM   3527 O OE2  . GLU A 1 220 ? -8.693  5.061   -13.955 1.000 10.022 0 235  GLU A OE2  1 ? 
ATOM   3528 H H    . GLU A 1 220 ? -12.887 3.734   -12.881 1.000 7.741  0 235  GLU A H    1 c 
ATOM   3529 H HA   . GLU A 1 220 ? -11.463 1.907   -11.503 1.000 7.479  0 235  GLU A HA   1 c 
ATOM   3530 H HB2  . GLU A 1 220 ? -11.463 4.750   -11.313 1.000 7.713  0 235  GLU A HB2  1 c 
ATOM   3531 H HB3  . GLU A 1 220 ? -10.473 3.873   -10.439 1.000 7.687  0 235  GLU A HB3  1 c 
ATOM   3532 H HG2  . GLU A 1 220 ? -9.269  3.195   -12.228 1.000 8.442  0 235  GLU A HG2  1 c 
ATOM   3533 H HG3  . GLU A 1 220 ? -10.474 3.398   -13.229 1.000 8.436  0 235  GLU A HG3  1 c 
ATOM   3534 N N    . VAL A 1 221 ? -13.817 3.282   -9.831  1.000 7.889  0 236  VAL A N    1 ? 
ATOM   3535 C CA   . VAL A 1 221 ? -14.697 3.028   -8.685  1.000 7.547  0 236  VAL A CA   1 ? 
ATOM   3536 C C    . VAL A 1 221 ? -15.259 1.608   -8.745  1.000 7.360  0 236  VAL A C    1 ? 
ATOM   3537 O O    . VAL A 1 221 ? -15.303 0.871   -7.737  1.000 7.732  0 236  VAL A O    1 ? 
ATOM   3538 C CB   . VAL A 1 221 ? -15.769 4.108   -8.531  1.000 7.961  0 236  VAL A CB   1 ? 
ATOM   3539 C CG1  . VAL A 1 221 ? -16.695 3.798   -7.347  1.000 8.651  0 236  VAL A CG1  1 ? 
ATOM   3540 C CG2  . VAL A 1 221 ? -15.163 5.494   -8.371  1.000 8.661  0 236  VAL A CG2  1 ? 
ATOM   3541 H H    . VAL A 1 221 ? -14.035 3.937   -10.429 1.000 7.740  0 236  VAL A H    1 c 
ATOM   3542 H HA   . VAL A 1 221 ? -14.137 3.075   -7.886  1.000 7.664  0 236  VAL A HA   1 c 
ATOM   3543 H HB   . VAL A 1 221 ? -16.312 4.103   -9.353  1.000 8.141  0 236  VAL A HB   1 c 
ATOM   3544 H HG11 . VAL A 1 221 ? -16.160 3.596   -6.560  1.000 8.445  0 236  VAL A HG11 1 c 
ATOM   3545 H HG12 . VAL A 1 221 ? -17.256 3.033   -7.562  1.000 8.438  0 236  VAL A HG12 1 c 
ATOM   3546 H HG13 . VAL A 1 221 ? -17.259 4.568   -7.164  1.000 8.444  0 236  VAL A HG13 1 c 
ATOM   3547 H HG21 . VAL A 1 221 ? -15.872 6.143   -8.227  1.000 8.449  0 236  VAL A HG21 1 c 
ATOM   3548 H HG22 . VAL A 1 221 ? -14.670 5.730   -9.173  1.000 8.452  0 236  VAL A HG22 1 c 
ATOM   3549 H HG23 . VAL A 1 221 ? -14.561 5.498   -7.609  1.000 8.449  0 236  VAL A HG23 1 c 
ATOM   3550 N N    . ALA A 1 222 ? -15.764 1.237   -9.930  1.000 7.529  0 237  ALA A N    1 ? 
ATOM   3551 C CA   . ALA A 1 222 ? -16.270 -0.121  -10.063 1.000 7.177  0 237  ALA A CA   1 ? 
ATOM   3552 C C    . ALA A 1 222 ? -15.206 -1.163  -9.706  1.000 7.663  0 237  ALA A C    1 ? 
ATOM   3553 O O    . ALA A 1 222 ? -15.517 -2.194  -9.090  1.000 7.831  0 237  ALA A O    1 ? 
ATOM   3554 C CB   . ALA A 1 222 ? -16.857 -0.339  -11.449 1.000 7.815  0 237  ALA A CB   1 ? 
ATOM   3555 H H    . ALA A 1 222 ? -15.800 1.814   -10.638 1.000 7.415  0 237  ALA A H    1 c 
ATOM   3556 H HA   . ALA A 1 222 ? -17.008 -0.224  -9.403  1.000 7.469  0 237  ALA A HA   1 c 
ATOM   3557 H HB1  . ALA A 1 222 ? -17.581 0.292   -11.600 1.000 7.622  0 237  ALA A HB1  1 c 
ATOM   3558 H HB2  . ALA A 1 222 ? -16.169 -0.203  -12.122 1.000 7.624  0 237  ALA A HB2  1 c 
ATOM   3559 H HB3  . ALA A 1 222 ? -17.201 -1.245  -11.521 1.000 7.622  0 237  ALA A HB3  1 c 
ATOM   3560 N N    . PHE A 1 223 ? -13.960 -0.946  -10.113 1.000 6.803  0 238  PHE A N    1 ? 
ATOM   3561 C CA   . PHE A 1 223 ? -12.871 -1.878  -9.798  1.000 7.035  0 238  PHE A CA   1 ? 
ATOM   3562 C C    . PHE A 1 223 ? -12.739 -2.046  -8.279  1.000 7.024  0 238  PHE A C    1 ? 
ATOM   3563 O O    . PHE A 1 223 ? -12.665 -3.187  -7.813  1.000 7.065  0 238  PHE A O    1 ? 
ATOM   3564 C CB   . PHE A 1 223 ? -11.554 -1.432  -10.436 1.000 7.379  0 238  PHE A CB   1 ? 
ATOM   3565 C CG   . PHE A 1 223 ? -10.379 -2.272  -9.987  1.000 8.005  0 238  PHE A CG   1 ? 
ATOM   3566 C CD1  . PHE A 1 223 ? -10.106 -3.474  -10.609 1.000 7.889  0 238  PHE A CD1  1 ? 
ATOM   3567 C CD2  . PHE A 1 223 ? -9.595  -1.884  -8.938  1.000 8.731  0 238  PHE A CD2  1 ? 
ATOM   3568 C CE1  . PHE A 1 223 ? -9.059  -4.280  -10.212 1.000 8.711  0 238  PHE A CE1  1 ? 
ATOM   3569 C CE2  . PHE A 1 223 ? -8.521  -2.643  -8.564  1.000 8.722  0 238  PHE A CE2  1 ? 
ATOM   3570 C CZ   . PHE A 1 223 ? -8.269  -3.871  -9.167  1.000 9.417  0 238  PHE A CZ   1 ? 
ATOM   3571 H H    . PHE A 1 223 ? -13.772 -0.201  -10.608 1.000 7.058  0 238  PHE A H    1 c 
ATOM   3572 H HA   . PHE A 1 223 ? -13.110 -2.762  -10.183 1.000 7.053  0 238  PHE A HA   1 c 
ATOM   3573 H HB2  . PHE A 1 223 ? -11.639 -1.493  -11.413 1.000 7.439  0 238  PHE A HB2  1 c 
ATOM   3574 H HB3  . PHE A 1 223 ? -11.388 -0.493  -10.197 1.000 7.445  0 238  PHE A HB3  1 c 
ATOM   3575 H HD1  . PHE A 1 223 ? -10.663 -3.759  -11.317 1.000 8.115  0 238  PHE A HD1  1 c 
ATOM   3576 H HD2  . PHE A 1 223 ? -9.757  -1.056  -8.514  1.000 8.549  0 238  PHE A HD2  1 c 
ATOM   3577 H HE1  . PHE A 1 223 ? -8.888  -5.096  -10.654 1.000 8.663  0 238  PHE A HE1  1 c 
ATOM   3578 H HE2  . PHE A 1 223 ? -7.988  -2.364  -7.837  1.000 8.870  0 238  PHE A HE2  1 c 
ATOM   3579 H HZ   . PHE A 1 223 ? -7.532  -4.394  -8.893  1.000 9.064  0 238  PHE A HZ   1 c 
ATOM   3580 N N    . MET A 1 224 ? -12.693 -0.940  -7.528  1.000 7.184  0 239  MET A N    1 ? 
ATOM   3581 C CA   . MET A 1 224 ? -12.497 -1.094  -6.087  1.000 7.149  0 239  MET A CA   1 ? 
ATOM   3582 C C    . MET A 1 224 ? -13.701 -1.783  -5.443  1.000 7.439  0 239  MET A C    1 ? 
ATOM   3583 O O    . MET A 1 224 ? -13.517 -2.447  -4.419  1.000 8.311  0 239  MET A O    1 ? 
ATOM   3584 C CB   . MET A 1 224 ? -12.220 0.252   -5.388  1.000 8.636  0 239  MET A CB   1 ? 
ATOM   3585 C CG   . MET A 1 224 ? -13.430 1.146   -5.100  1.000 8.411  0 239  MET A CG   1 ? 
ATOM   3586 S SD   . MET A 1 224 ? -12.978 2.590   -4.103  1.000 8.759  0 239  MET A SD   1 ? 
ATOM   3587 C CE   . MET A 1 224 ? -12.441 3.716   -5.402  1.000 10.267 0 239  MET A CE   1 ? 
ATOM   3588 H H    . MET A 1 224 ? -12.777 -0.108  -7.896  1.000 7.144  0 239  MET A H    1 c 
ATOM   3589 H HA   . MET A 1 224 ? -11.711 -1.683  -5.955  1.000 7.462  0 239  MET A HA   1 c 
ATOM   3590 H HB2  . MET A 1 224 ? -11.768 0.063   -4.538  1.000 8.223  0 239  MET A HB2  1 c 
ATOM   3591 H HB3  . MET A 1 224 ? -11.590 0.757   -5.945  1.000 8.223  0 239  MET A HB3  1 c 
ATOM   3592 H HG2  . MET A 1 224 ? -13.814 1.454   -5.942  1.000 8.525  0 239  MET A HG2  1 c 
ATOM   3593 H HG3  . MET A 1 224 ? -14.112 0.635   -4.624  1.000 8.535  0 239  MET A HG3  1 c 
ATOM   3594 H HE1  . MET A 1 224 ? -11.992 4.483   -5.000  1.000 9.854  0 239  MET A HE1  1 c 
ATOM   3595 H HE2  . MET A 1 224 ? -11.825 3.253   -5.999  1.000 9.858  0 239  MET A HE2  1 c 
ATOM   3596 H HE3  . MET A 1 224 ? -13.216 4.021   -5.908  1.000 9.847  0 239  MET A HE3  1 c 
ATOM   3597 N N    . VAL A 1 225 ? -14.902 -1.615  -5.993  1.000 6.695  0 240  VAL A N    1 ? 
ATOM   3598 C CA   . VAL A 1 225 ? -16.072 -2.307  -5.479  1.000 7.206  0 240  VAL A CA   1 ? 
ATOM   3599 C C    . VAL A 1 225 ? -15.976 -3.802  -5.756  1.000 7.843  0 240  VAL A C    1 ? 
ATOM   3600 O O    . VAL A 1 225 ? -16.192 -4.626  -4.861  1.000 8.839  0 240  VAL A O    1 ? 
ATOM   3601 C CB   . VAL A 1 225 ? -17.341 -1.681  -6.055  1.000 8.160  0 240  VAL A CB   1 ? 
ATOM   3602 C CG1  . VAL A 1 225 ? -18.554 -2.522  -5.718  1.000 8.778  0 240  VAL A CG1  1 ? 
ATOM   3603 C CG2  . VAL A 1 225 ? -17.513 -0.267  -5.532  1.000 8.360  0 240  VAL A CG2  1 ? 
ATOM   3604 H H    . VAL A 1 225 ? -14.999 -1.050  -6.704  1.000 7.013  0 240  VAL A H    1 c 
ATOM   3605 H HA   . VAL A 1 225 ? -16.091 -2.182  -4.510  1.000 7.394  0 240  VAL A HA   1 c 
ATOM   3606 H HB   . VAL A 1 225 ? -17.241 -1.647  -7.036  1.000 8.111  0 240  VAL A HB   1 c 
ATOM   3607 H HG11 . VAL A 1 225 ? -18.525 -2.773  -4.779  1.000 8.587  0 240  VAL A HG11 1 c 
ATOM   3608 H HG12 . VAL A 1 225 ? -18.559 -3.324  -6.267  1.000 8.591  0 240  VAL A HG12 1 c 
ATOM   3609 H HG13 . VAL A 1 225 ? -19.362 -2.009  -5.890  1.000 8.588  0 240  VAL A HG13 1 c 
ATOM   3610 H HG21 . VAL A 1 225 ? -18.294 0.139   -5.945  1.000 8.295  0 240  VAL A HG21 1 c 
ATOM   3611 H HG22 . VAL A 1 225 ? -16.725 0.259   -5.745  1.000 8.278  0 240  VAL A HG22 1 c 
ATOM   3612 H HG23 . VAL A 1 225 ? -17.634 -0.291  -4.568  1.000 8.295  0 240  VAL A HG23 1 c 
ATOM   3613 N N    . CYS A 1 226 ? -15.596 -4.188  -6.982  1.000 7.953  0 241  CYS A N    1 ? 
ATOM   3614 C CA   . CYS A 1 226 ? -15.345 -5.593  -7.262  1.000 7.352  0 241  CYS A CA   1 ? 
ATOM   3615 C C    . CYS A 1 226 ? -14.222 -6.137  -6.369  1.000 7.892  0 241  CYS A C    1 ? 
ATOM   3616 O O    . CYS A 1 226 ? -14.220 -7.353  -6.068  1.000 9.151  0 241  CYS A O    1 ? 
ATOM   3617 C CB   . CYS A 1 226 ? -15.013 -5.814  -8.736  1.000 7.941  0 241  CYS A CB   1 ? 
ATOM   3618 S SG   . CYS A 1 226 ? -16.374 -5.447  -9.878  1.000 8.625  0 241  CYS A SG   1 ? 
ATOM   3619 H H    . CYS A 1 226 ? -15.496 -3.572  -7.650  1.000 7.778  0 241  CYS A H    1 c 
ATOM   3620 H HA   . CYS A 1 226 ? -16.175 -6.095  -7.057  1.000 7.677  0 241  CYS A HA   1 c 
ATOM   3621 H HB2  . CYS A 1 226 ? -14.247 -5.247  -8.978  1.000 7.919  0 241  CYS A HB2  1 c 
ATOM   3622 H HB3  . CYS A 1 226 ? -14.744 -6.750  -8.865  1.000 7.915  0 241  CYS A HB3  1 c 
ATOM   3623 H HG   . CYS A 1 226 ? -15.795 -5.717  -10.908 0.000 8.630  0 241  CYS A HG   1 c 
ATOM   3624 N N    . ALA A 1 227 ? -13.257 -5.306  -6.012  1.000 8.622  0 242  ALA A N    1 ? 
ATOM   3625 C CA   . ALA A 1 227 ? -12.141 -5.731  -5.192  1.000 8.224  0 242  ALA A CA   1 ? 
ATOM   3626 C C    . ALA A 1 227 ? -12.509 -5.959  -3.733  1.000 8.158  0 242  ALA A C    1 ? 
ATOM   3627 O O    . ALA A 1 227 ? -11.681 -6.536  -3.021  1.000 8.487  0 242  ALA A O    1 ? 
ATOM   3628 C CB   . ALA A 1 227 ? -11.000 -4.765  -5.308  1.000 8.629  0 242  ALA A CB   1 ? 
ATOM   3629 H H    . ALA A 1 227 ? -13.280 -4.440  -6.304  1.000 8.336  0 242  ALA A H    1 c 
ATOM   3630 H HA   . ALA A 1 227 ? -11.831 -6.607  -5.553  1.000 8.363  0 242  ALA A HA   1 c 
ATOM   3631 H HB1  . ALA A 1 227 ? -10.757 -4.657  -6.243  1.000 8.506  0 242  ALA A HB1  1 c 
ATOM   3632 H HB2  . ALA A 1 227 ? -11.262 -3.903  -4.943  1.000 8.506  0 242  ALA A HB2  1 c 
ATOM   3633 H HB3  . ALA A 1 227 ? -10.234 -5.103  -4.815  1.000 8.506  0 242  ALA A HB3  1 c 
ATOM   3634 N N    . ILE A 1 228 ? -13.693 -5.532  -3.266  1.000 7.962  0 243  ILE A N    1 ? 
ATOM   3635 C CA   . ILE A 1 228 ? -14.127 -5.883  -1.908  1.000 7.988  0 243  ILE A CA   1 ? 
ATOM   3636 C C    . ILE A 1 228 ? -14.033 -7.401  -1.757  1.000 8.202  0 243  ILE A C    1 ? 
ATOM   3637 O O    . ILE A 1 228 ? -14.401 -8.143  -2.667  1.000 9.744  0 243  ILE A O    1 ? 
ATOM   3638 C CB   . ILE A 1 228 ? -15.556 -5.374  -1.654  1.000 8.287  0 243  ILE A CB   1 ? 
ATOM   3639 C CG1  . ILE A 1 228 ? -15.652 -3.886  -1.669  1.000 8.592  0 243  ILE A CG1  1 ? 
ATOM   3640 C CG2  . ILE A 1 228 ? -16.071 -5.913  -0.307  1.000 9.011  0 243  ILE A CG2  1 ? 
ATOM   3641 C CD1  . ILE A 1 228 ? -17.055 -3.322  -1.743  1.000 9.554  0 243  ILE A CD1  1 ? 
ATOM   3642 H H    . ILE A 1 228 ? -14.236 -5.019  -3.791  1.000 8.027  0 243  ILE A H    1 c 
ATOM   3643 H HA   . ILE A 1 228 ? -13.523 -5.460  -1.267  1.000 8.083  0 243  ILE A HA   1 c 
ATOM   3644 H HB   . ILE A 1 228 ? -16.132 -5.721  -2.363  1.000 8.424  0 243  ILE A HB   1 c 
ATOM   3645 H HG12 . ILE A 1 228 ? -15.224 -3.542  -0.858  1.000 8.728  0 243  ILE A HG12 1 c 
ATOM   3646 H HG13 . ILE A 1 228 ? -15.144 -3.549  -2.434  1.000 8.716  0 243  ILE A HG13 1 c 
ATOM   3647 H HG21 . ILE A 1 228 ? -16.937 -5.521  -0.106  1.000 8.801  0 243  ILE A HG21 1 c 
ATOM   3648 H HG22 . ILE A 1 228 ? -15.444 -5.682  0.399   1.000 8.799  0 243  ILE A HG22 1 c 
ATOM   3649 H HG23 . ILE A 1 228 ? -16.162 -6.880  -0.353  1.000 8.793  0 243  ILE A HG23 1 c 
ATOM   3650 H HD11 . ILE A 1 228 ? -17.527 -3.720  -2.500  1.000 9.258  0 243  ILE A HD11 1 c 
ATOM   3651 H HD12 . ILE A 1 228 ? -17.009 -2.354  -1.864  1.000 9.258  0 243  ILE A HD12 1 c 
ATOM   3652 H HD13 . ILE A 1 228 ? -17.539 -3.521  -0.919  1.000 9.255  0 243  ILE A HD13 1 c 
ATOM   3653 N N    . ASN A 1 229 ? -13.529 -7.834  -0.595  1.000 8.589  0 244  ASN A N    1 ? 
ATOM   3654 C CA   . ASN A 1 229 ? -13.378 -9.256  -0.300  1.000 9.525  0 244  ASN A CA   1 ? 
ATOM   3655 C C    . ASN A 1 229 ? -14.178 -9.584  0.961   1.000 10.256 0 244  ASN A C    1 ? 
ATOM   3656 O O    . ASN A 1 229 ? -13.740 -9.283  2.066   1.000 10.044 0 244  ASN A O    1 ? 
ATOM   3657 C CB   . ASN A 1 229 ? -11.923 -9.642  -0.155  1.000 10.489 0 244  ASN A CB   1 ? 
ATOM   3658 C CG   . ASN A 1 229 ? -11.769 -11.143 -0.063  1.000 12.172 0 244  ASN A CG   1 ? 
ATOM   3659 O OD1  . ASN A 1 229 ? -12.740 -11.863 0.261   1.000 13.551 0 244  ASN A OD1  1 ? 
ATOM   3660 N ND2  . ASN A 1 229 ? -10.558 -11.614 -0.310  1.000 13.390 0 244  ASN A ND2  1 ? 
ATOM   3661 H H    . ASN A 1 229 ? -13.274 -7.226  0.037   1.000 8.688  0 244  ASN A H    1 c 
ATOM   3662 H HA   . ASN A 1 229 ? -13.741 -9.772  -1.052  1.000 9.705  0 244  ASN A HA   1 c 
ATOM   3663 H HB2  . ASN A 1 229 ? -11.421 -9.311  -0.927  1.000 10.628 0 244  ASN A HB2  1 c 
ATOM   3664 H HB3  . ASN A 1 229 ? -11.554 -9.228  0.650   1.000 10.609 0 244  ASN A HB3  1 c 
ATOM   3665 H HD21 . ASN A 1 229 ? -9.871  -11.057 -0.385  1.000 12.962 0 244  ASN A HD21 1 c 
ATOM   3666 H HD22 . ASN A 1 229 ? -10.434 -12.487 -0.400  1.000 12.993 0 244  ASN A HD22 1 c 
ATOM   3667 N N    . PRO A 1 230 ? -15.394 -10.136 0.812   1.000 11.666 0 245  PRO A N    1 ? 
ATOM   3668 C CA   . PRO A 1 230 ? -16.217 -10.467 1.972   1.000 12.581 0 245  PRO A CA   1 ? 
ATOM   3669 C C    . PRO A 1 230 ? -15.745 -11.633 2.818   1.000 12.667 0 245  PRO A C    1 ? 
ATOM   3670 O O    . PRO A 1 230 ? -16.356 -11.883 3.882   1.000 13.604 0 245  PRO A O    1 ? 
ATOM   3671 C CB   . PRO A 1 230 ? -17.571 -10.785 1.320   1.000 13.913 0 245  PRO A CB   1 ? 
ATOM   3672 C CG   . PRO A 1 230 ? -17.569 -10.064 0.034   1.000 15.948 0 245  PRO A CG   1 ? 
ATOM   3673 C CD   . PRO A 1 230 ? -16.108 -10.301 -0.457  1.000 13.092 0 245  PRO A CD   1 ? 
ATOM   3674 H HA   . PRO A 1 230 ? -16.308 -9.660  2.539   1.000 12.626 0 245  PRO A HA   1 c 
ATOM   3675 H HB2  . PRO A 1 230 ? -17.670 -11.756 1.175   1.000 14.039 0 245  PRO A HB2  1 c 
ATOM   3676 H HB3  . PRO A 1 230 ? -18.314 -10.478 1.891   1.000 14.046 0 245  PRO A HB3  1 c 
ATOM   3677 H HG2  . PRO A 1 230 ? -18.221 -10.444 -0.591  1.000 14.779 0 245  PRO A HG2  1 c 
ATOM   3678 H HG3  . PRO A 1 230 ? -17.753 -9.110  0.158   1.000 14.796 0 245  PRO A HG3  1 c 
ATOM   3679 H HD2  . PRO A 1 230 ? -15.992 -11.205 -0.826  1.000 13.279 0 245  PRO A HD2  1 c 
ATOM   3680 H HD3  . PRO A 1 230 ? -15.843 -9.627  -1.119  1.000 13.194 0 245  PRO A HD3  1 c 
ATOM   3681 N N    A SER A 1 231 ? -14.635 -12.282 2.460   0.500 12.767 0 246  SER A N    1 ? 
ATOM   3682 N N    B SER A 1 231 ? -14.781 -12.421 2.354   0.500 12.899 0 246  SER A N    1 ? 
ATOM   3683 C CA   A SER A 1 231 ? -14.179 -13.492 3.140   0.500 14.452 0 246  SER A CA   1 ? 
ATOM   3684 C CA   B SER A 1 231 ? -14.433 -13.663 3.041   0.500 15.027 0 246  SER A CA   1 ? 
ATOM   3685 C C    A SER A 1 231 ? -13.760 -13.201 4.565   0.500 15.512 0 246  SER A C    1 ? 
ATOM   3686 C C    B SER A 1 231 ? -13.771 -13.400 4.394   0.500 15.861 0 246  SER A C    1 ? 
ATOM   3687 O O    A SER A 1 231 ? -12.884 -12.385 4.866   0.500 12.910 0 246  SER A O    1 ? 
ATOM   3688 O O    B SER A 1 231 ? -12.740 -12.750 4.463   0.500 16.496 0 246  SER A O    1 ? 
ATOM   3689 C CB   A SER A 1 231 ? -13.039 -14.154 2.433   0.500 14.949 0 246  SER A CB   1 ? 
ATOM   3690 C CB   B SER A 1 231 ? -13.563 -14.518 2.161   0.500 15.881 0 246  SER A CB   1 ? 
ATOM   3691 O OG   A SER A 1 231 ? -13.441 -14.669 1.171   0.500 18.633 0 246  SER A OG   1 ? 
ATOM   3692 O OG   B SER A 1 231 ? -12.904 -15.560 2.873   0.500 18.271 0 246  SER A OG   1 ? 
ATOM   3693 H H    A SER A 1 231 ? -14.140 -11.968 1.760   0.500 13.068 0 246  SER A H    1 c 
ATOM   3694 H H    B SER A 1 231 ? -14.329 -12.196 1.593   0.500 13.254 0 246  SER A H    1 c 
ATOM   3695 H HA   A SER A 1 231 ? -14.938 -14.129 3.165   0.500 14.421 0 246  SER A HA   1 c 
ATOM   3696 H HA   B SER A 1 231 ? -15.273 -14.158 3.207   0.500 14.909 0 246  SER A HA   1 c 
ATOM   3697 H HB2  A SER A 1 231 ? -12.320 -13.507 2.305   0.500 15.639 0 246  SER A HB2  1 c 
ATOM   3698 H HB2  B SER A 1 231 ? -14.114 -14.911 1.457   0.500 16.211 0 246  SER A HB2  1 c 
ATOM   3699 H HB3  A SER A 1 231 ? -12.698 -14.882 2.985   0.500 15.725 0 246  SER A HB3  1 c 
ATOM   3700 H HB3  B SER A 1 231 ? -12.894 -13.953 1.733   0.500 16.198 0 246  SER A HB3  1 c 
ATOM   3701 H HG   A SER A 1 231 ? -12.768 -15.033 0.804   0.000 18.700 0 246  SER A HG   1 c 
ATOM   3702 H HG   B SER A 1 231 ? -12.431 -16.002 2.325   0.000 18.280 0 246  SER A HG   1 c 
ATOM   3703 N N    . ILE A 1 232 ? -14.365 -13.952 5.482   1.000 16.069 0 247  ILE A N    1 ? 
ATOM   3704 C CA   . ILE A 1 232 ? -13.835 -13.940 6.837   1.000 16.328 0 247  ILE A CA   1 ? 
ATOM   3705 C C    . ILE A 1 232 ? -12.841 -15.081 6.981   1.000 19.617 0 247  ILE A C    1 ? 
ATOM   3706 O O    . ILE A 1 232 ? -11.751 -14.883 7.517   1.000 20.630 0 247  ILE A O    1 ? 
ATOM   3707 C CB   . ILE A 1 232 ? -14.975 -14.057 7.864   1.000 17.001 0 247  ILE A CB   1 ? 
ATOM   3708 C CG1  . ILE A 1 232 ? -15.825 -12.825 7.845   1.000 15.966 0 247  ILE A CG1  1 ? 
ATOM   3709 C CG2  . ILE A 1 232 ? -14.407 -14.328 9.252   1.000 18.686 0 247  ILE A CG2  1 ? 
ATOM   3710 C CD1  . ILE A 1 232 ? -17.156 -12.927 8.579   1.000 15.828 0 247  ILE A CD1  1 ? 
ATOM   3711 H H    . ILE A 1 232 ? -15.142 -14.405 5.322   1.000 15.971 0 247  ILE A H    1 c 
ATOM   3712 H HA   . ILE A 1 232 ? -13.368 -13.096 6.990   1.000 16.935 0 247  ILE A HA   1 c 
ATOM   3713 H HB   . ILE A 1 232 ? -15.536 -14.816 7.610   1.000 16.972 0 247  ILE A HB   1 c 
ATOM   3714 H HG12 . ILE A 1 232 ? -15.311 -12.092 8.241   1.000 16.130 0 247  ILE A HG12 1 c 
ATOM   3715 H HG13 . ILE A 1 232 ? -16.005 -12.587 6.913   1.000 16.162 0 247  ILE A HG13 1 c 
ATOM   3716 H HG21 . ILE A 1 232 ? -15.109 -14.233 9.917   1.000 18.145 0 247  ILE A HG21 1 c 
ATOM   3717 H HG22 . ILE A 1 232 ? -13.695 -13.694 9.443   1.000 18.168 0 247  ILE A HG22 1 c 
ATOM   3718 H HG23 . ILE A 1 232 ? -14.052 -15.232 9.291   1.000 18.175 0 247  ILE A HG23 1 c 
ATOM   3719 H HD11 . ILE A 1 232 ? -17.668 -13.677 8.223   1.000 15.929 0 247  ILE A HD11 1 c 
ATOM   3720 H HD12 . ILE A 1 232 ? -17.661 -12.101 8.450   1.000 15.888 0 247  ILE A HD12 1 c 
ATOM   3721 H HD13 . ILE A 1 232 ? -17.000 -13.064 9.532   1.000 15.909 0 247  ILE A HD13 1 c 
ATOM   3722 N N    . ASP A 1 233 ? -13.239 -16.250 6.484   1.000 20.662 0 248  ASP A N    1 ? 
ATOM   3723 C CA   . ASP A 1 233 ? -12.393 -17.439 6.465   1.000 23.529 0 248  ASP A CA   1 ? 
ATOM   3724 C C    . ASP A 1 233 ? -12.871 -18.328 5.328   1.000 25.825 0 248  ASP A C    1 ? 
ATOM   3725 O O    . ASP A 1 233 ? -13.771 -17.965 4.565   1.000 28.847 0 248  ASP A O    1 ? 
ATOM   3726 C CB   . ASP A 1 233 ? -12.339 -18.101 7.843   1.000 24.915 0 248  ASP A CB   1 ? 
ATOM   3727 C CG   . ASP A 1 233 ? -13.645 -18.662 8.390   1.000 23.250 0 248  ASP A CG   1 ? 
ATOM   3728 O OD1  . ASP A 1 233 ? -14.451 -19.165 7.592   1.000 25.767 0 248  ASP A OD1  1 ? 
ATOM   3729 O OD2  . ASP A 1 233 ? -13.827 -18.592 9.620   1.000 28.273 0 248  ASP A OD2  1 ? 
ATOM   3730 H H    . ASP A 1 233 ? -14.088 -16.319 6.151   1.000 20.924 0 248  ASP A H    1 c 
ATOM   3731 H HA   . ASP A 1 233 ? -11.475 -17.153 6.256   1.000 23.552 0 248  ASP A HA   1 c 
ATOM   3732 H HB2  . ASP A 1 233 ? -11.684 -18.829 7.820   1.000 24.278 0 248  ASP A HB2  1 c 
ATOM   3733 H HB3  . ASP A 1 233 ? -12.012 -17.435 8.484   1.000 24.219 0 248  ASP A HB3  1 c 
ATOM   3734 N N    . LEU A 1 234 ? -12.296 -19.548 5.246   1.000 30.661 0 249  LEU A N    1 ? 
ATOM   3735 C CA   . LEU A 1 234 ? -12.590 -20.443 4.136   1.000 34.520 0 249  LEU A CA   1 ? 
ATOM   3736 C C    . LEU A 1 234 ? -14.066 -20.852 4.124   1.000 30.545 0 249  LEU A C    1 ? 
ATOM   3737 O O    . LEU A 1 234 ? -14.602 -21.157 3.064   1.000 31.512 0 249  LEU A O    1 ? 
ATOM   3738 C CB   . LEU A 1 234 ? -11.626 -21.636 4.202   1.000 42.510 0 249  LEU A CB   1 ? 
ATOM   3739 C CG   . LEU A 1 234 ? -10.144 -21.299 3.966   1.000 50.861 0 249  LEU A CG   1 ? 
ATOM   3740 C CD1  . LEU A 1 234 ? -9.171  -22.449 4.259   1.000 55.257 0 249  LEU A CD1  1 ? 
ATOM   3741 C CD2  . LEU A 1 234 ? -9.927  -20.812 2.532   1.000 54.903 0 249  LEU A CD2  1 ? 
ATOM   3742 H H    . LEU A 1 234 ? -11.708 -19.819 5.890   1.000 30.431 0 249  LEU A H    1 c 
ATOM   3743 H HA   . LEU A 1 234 ? -12.417 -19.945 3.299   1.000 34.363 0 249  LEU A HA   1 c 
ATOM   3744 H HB2  . LEU A 1 234 ? -11.713 -22.055 5.089   1.000 42.130 0 249  LEU A HB2  1 c 
ATOM   3745 H HB3  . LEU A 1 234 ? -11.907 -22.297 3.527   1.000 42.203 0 249  LEU A HB3  1 c 
ATOM   3746 H HG   . LEU A 1 234 ? -9.905  -20.551 4.571   1.000 50.379 0 249  LEU A HG   1 c 
ATOM   3747 H HD11 . LEU A 1 234 ? -9.233  -22.695 5.197   1.000 53.931 0 249  LEU A HD11 1 c 
ATOM   3748 H HD12 . LEU A 1 234 ? -8.263  -22.166 4.059   1.000 53.928 0 249  LEU A HD12 1 c 
ATOM   3749 H HD13 . LEU A 1 234 ? -9.399  -23.216 3.708   1.000 53.931 0 249  LEU A HD13 1 c 
ATOM   3750 H HD21 . LEU A 1 234 ? -10.356 -19.948 2.413   1.000 53.382 0 249  LEU A HD21 1 c 
ATOM   3751 H HD22 . LEU A 1 234 ? -10.312 -21.452 1.910   1.000 53.614 0 249  LEU A HD22 1 c 
ATOM   3752 H HD23 . LEU A 1 234 ? -8.975  -20.726 2.358   1.000 53.623 0 249  LEU A HD23 1 c 
ATOM   3753 N N    . HIS A 1 235 ? -14.751 -20.810 5.276   1.000 30.852 0 250  HIS A N    1 ? 
ATOM   3754 C CA   . HIS A 1 235 ? -16.126 -21.298 5.342   1.000 34.068 0 250  HIS A CA   1 ? 
ATOM   3755 C C    . HIS A 1 235 ? -17.134 -20.183 5.596   1.000 31.356 0 250  HIS A C    1 ? 
ATOM   3756 O O    . HIS A 1 235 ? -18.320 -20.482 5.680   1.000 29.256 0 250  HIS A O    1 ? 
ATOM   3757 C CB   . HIS A 1 235 ? -16.372 -22.246 6.526   1.000 38.747 0 250  HIS A CB   1 ? 
ATOM   3758 C CG   . HIS A 1 235 ? -15.296 -23.245 6.737   1.000 42.995 0 250  HIS A CG   1 ? 
ATOM   3759 N ND1  . HIS A 1 235 ? -14.338 -23.045 7.709   1.000 44.946 0 250  HIS A ND1  1 ? 
ATOM   3760 C CD2  . HIS A 1 235 ? -15.020 -24.416 6.147   1.000 45.874 0 250  HIS A CD2  1 ? 
ATOM   3761 C CE1  . HIS A 1 235 ? -13.493 -24.066 7.688   1.000 48.556 0 250  HIS A CE1  1 ? 
ATOM   3762 N NE2  . HIS A 1 235 ? -13.890 -24.910 6.752   1.000 45.987 0 250  HIS A NE2  1 ? 
ATOM   3763 H H    . HIS A 1 235 ? -14.356 -20.492 6.036   1.000 31.401 0 250  HIS A H    1 c 
ATOM   3764 H HA   . HIS A 1 235 ? -16.364 -21.754 4.498   1.000 33.660 0 250  HIS A HA   1 c 
ATOM   3765 H HB2  . HIS A 1 235 ? -16.470 -21.710 7.344   1.000 38.513 0 250  HIS A HB2  1 c 
ATOM   3766 H HB3  . HIS A 1 235 ? -17.219 -22.720 6.378   1.000 38.505 0 250  HIS A HB3  1 c 
ATOM   3767 H HD1  . HIS A 1 235 ? -14.290 -22.336 8.252   0.000 45.100 0 250  HIS A HD1  1 c 
ATOM   3768 H HD2  . HIS A 1 235 ? -15.493 -24.821 5.448   1.000 45.201 0 250  HIS A HD2  1 c 
ATOM   3769 H HE1  . HIS A 1 235 ? -12.750 -24.174 8.254   1.000 46.995 0 250  HIS A HE1  1 c 
ATOM   3770 H HE2  . HIS A 1 235 ? -13.483 -25.656 6.562   0.000 45.950 0 250  HIS A HE2  1 c 
ATOM   3771 N N    . THR A 1 236 ? -16.677 -18.923 5.733   1.000 25.805 0 251  THR A N    1 ? 
ATOM   3772 C CA   . THR A 1 236 ? -17.540 -17.869 6.231   1.000 21.849 0 251  THR A CA   1 ? 
ATOM   3773 C C    . THR A 1 236 ? -17.313 -16.582 5.432   1.000 18.627 0 251  THR A C    1 ? 
ATOM   3774 O O    . THR A 1 236 ? -16.179 -16.099 5.366   1.000 18.785 0 251  THR A O    1 ? 
ATOM   3775 C CB   . THR A 1 236 ? -17.253 -17.592 7.702   1.000 23.914 0 251  THR A CB   1 ? 
ATOM   3776 O OG1  . THR A 1 236 ? -17.101 -18.818 8.430   1.000 29.403 0 251  THR A OG1  1 ? 
ATOM   3777 C CG2  . THR A 1 236 ? -18.359 -16.761 8.318   1.000 26.271 0 251  THR A CG2  1 ? 
ATOM   3778 H H    . THR A 1 236 ? -15.816 -18.720 5.504   1.000 26.052 0 251  THR A H    1 c 
ATOM   3779 H HA   . THR A 1 236 ? -18.475 -18.148 6.136   1.000 22.347 0 251  THR A HA   1 c 
ATOM   3780 H HB   . THR A 1 236 ? -16.413 -17.079 7.772   1.000 24.845 0 251  THR A HB   1 c 
ATOM   3781 H HG1  . THR A 1 236 ? -17.826 -19.281 8.373   0.000 29.360 0 251  THR A HG1  1 c 
ATOM   3782 H HG21 . THR A 1 236 ? -18.190 -16.650 9.269   1.000 25.513 0 251  THR A HG21 1 c 
ATOM   3783 H HG22 . THR A 1 236 ? -19.212 -17.211 8.192   1.000 25.496 0 251  THR A HG22 1 c 
ATOM   3784 H HG23 . THR A 1 236 ? -18.389 -15.888 7.892   1.000 25.417 0 251  THR A HG23 1 c 
ATOM   3785 N N    . ASP A 1 237 ? -18.404 -16.036 4.882   1.000 15.547 0 252  ASP A N    1 ? 
ATOM   3786 C CA   . ASP A 1 237 ? -18.398 -14.684 4.329   1.000 14.820 0 252  ASP A CA   1 ? 
ATOM   3787 C C    . ASP A 1 237 ? -19.140 -13.724 5.247   1.000 14.481 0 252  ASP A C    1 ? 
ATOM   3788 O O    . ASP A 1 237 ? -20.129 -14.103 5.876   1.000 16.496 0 252  ASP A O    1 ? 
ATOM   3789 C CB   . ASP A 1 237 ? -19.016 -14.655 2.943   1.000 17.075 0 252  ASP A CB   1 ? 
ATOM   3790 C CG   . ASP A 1 237 ? -18.232 -15.398 1.887   1.000 22.713 0 252  ASP A CG   1 ? 
ATOM   3791 O OD1  . ASP A 1 237 ? -17.014 -15.403 1.984   1.000 20.635 0 252  ASP A OD1  1 ? 
ATOM   3792 O OD2  . ASP A 1 237 ? -18.875 -15.924 0.967   1.000 33.187 0 252  ASP A OD2  1 ? 
ATOM   3793 H H    . ASP A 1 237 ? -19.178 -16.521 4.846   1.000 16.142 0 252  ASP A H    1 c 
ATOM   3794 H HA   . ASP A 1 237 ? -17.465 -14.382 4.252   1.000 15.328 0 252  ASP A HA   1 c 
ATOM   3795 H HB2  . ASP A 1 237 ? -19.914 -15.045 2.991   1.000 17.733 0 252  ASP A HB2  1 c 
ATOM   3796 H HB3  . ASP A 1 237 ? -19.107 -13.722 2.656   1.000 17.661 0 252  ASP A HB3  1 c 
ATOM   3797 N N    . SER A 1 238 ? -18.709 -12.460 5.266   1.000 11.839 0 253  SER A N    1 ? 
ATOM   3798 C CA   . SER A 1 238 ? -19.435 -11.356 5.885   1.000 10.538 0 253  SER A CA   1 ? 
ATOM   3799 C C    . SER A 1 238 ? -20.698 -11.017 5.090   1.000 11.079 0 253  SER A C    1 ? 
ATOM   3800 O O    . SER A 1 238 ? -20.617 -10.601 3.938   1.000 11.489 0 253  SER A O    1 ? 
ATOM   3801 C CB   . SER A 1 238 ? -18.529 -10.142 5.977   1.000 10.836 0 253  SER A CB   1 ? 
ATOM   3802 O OG   . SER A 1 238 ? -19.271 -8.965  6.242   1.000 11.012 0 253  SER A OG   1 ? 
ATOM   3803 H H    . SER A 1 238 ? -17.908 -12.275 4.867   1.000 12.120 0 253  SER A H    1 c 
ATOM   3804 H HA   . SER A 1 238 ? -19.698 -11.627 6.801   1.000 10.957 0 253  SER A HA   1 c 
ATOM   3805 H HB2  . SER A 1 238 ? -17.876 -10.280 6.689   1.000 10.810 0 253  SER A HB2  1 c 
ATOM   3806 H HB3  . SER A 1 238 ? -18.045 -10.035 5.136   1.000 10.810 0 253  SER A HB3  1 c 
ATOM   3807 H HG   . SER A 1 238 ? -18.735 -8.313  6.287   0.000 11.010 0 253  SER A HG   1 c 
ATOM   3808 N N    . LEU A 1 239 ? -21.876 -11.220 5.677   1.000 11.009 0 254  LEU A N    1 ? 
ATOM   3809 C CA   . LEU A 1 239 ? -23.111 -10.847 5.021   1.000 10.830 0 254  LEU A CA   1 ? 
ATOM   3810 C C    . LEU A 1 239 ? -23.120 -9.342  4.777   1.000 10.878 0 254  LEU A C    1 ? 
ATOM   3811 O O    . LEU A 1 239 ? -23.743 -8.860  3.829   1.000 11.584 0 254  LEU A O    1 ? 
ATOM   3812 C CB   . LEU A 1 239 ? -24.299 -11.274 5.908   1.000 11.614 0 254  LEU A CB   1 ? 
ATOM   3813 C CG   . LEU A 1 239 ? -24.492 -12.784 6.038   1.000 14.041 0 254  LEU A CG   1 ? 
ATOM   3814 C CD1  . LEU A 1 239 ? -25.640 -13.000 7.024   1.000 14.836 0 254  LEU A CD1  1 ? 
ATOM   3815 C CD2  . LEU A 1 239 ? -24.837 -13.502 4.725   1.000 18.057 0 254  LEU A CD2  1 ? 
ATOM   3816 H H    . LEU A 1 239 ? -21.910 -11.599 6.508   1.000 11.029 0 254  LEU A H    1 c 
ATOM   3817 H HA   . LEU A 1 239 ? -23.162 -11.316 4.150   1.000 11.070 0 254  LEU A HA   1 c 
ATOM   3818 H HB2  . LEU A 1 239 ? -24.164 -10.897 6.808   1.000 11.962 0 254  LEU A HB2  1 c 
ATOM   3819 H HB3  . LEU A 1 239 ? -25.122 -10.884 5.532   1.000 11.938 0 254  LEU A HB3  1 c 
ATOM   3820 H HG   . LEU A 1 239 ? -23.665 -13.181 6.416   1.000 14.319 0 254  LEU A HG   1 c 
ATOM   3821 H HD11 . LEU A 1 239 ? -25.404 -12.619 7.887   1.000 14.578 0 254  LEU A HD11 1 c 
ATOM   3822 H HD12 . LEU A 1 239 ? -25.806 -13.952 7.126   1.000 14.593 0 254  LEU A HD12 1 c 
ATOM   3823 H HD13 . LEU A 1 239 ? -26.443 -12.566 6.689   1.000 14.593 0 254  LEU A HD13 1 c 
ATOM   3824 H HD21 . LEU A 1 239 ? -24.090 -13.429 4.108   1.000 16.721 0 254  LEU A HD21 1 c 
ATOM   3825 H HD22 . LEU A 1 239 ? -25.625 -13.095 4.329   1.000 16.760 0 254  LEU A HD22 1 c 
ATOM   3826 H HD23 . LEU A 1 239 ? -25.014 -14.441 4.905   1.000 16.760 0 254  LEU A HD23 1 c 
ATOM   3827 N N    . GLU A 1 240 ? -22.531 -8.574  5.707   1.000 10.176 0 255  GLU A N    1 ? 
ATOM   3828 C CA   . GLU A 1 240 ? -22.523 -7.122  5.647   1.000 9.626  0 255  GLU A CA   1 ? 
ATOM   3829 C C    . GLU A 1 240 ? -21.747 -6.701  4.384   1.000 10.730 0 255  GLU A C    1 ? 
ATOM   3830 O O    . GLU A 1 240 ? -22.200 -5.821  3.637   1.000 10.928 0 255  GLU A O    1 ? 
ATOM   3831 C CB   . GLU A 1 240 ? -21.893 -6.545  6.909   1.000 10.584 0 255  GLU A CB   1 ? 
ATOM   3832 C CG   . GLU A 1 240 ? -22.508 -6.979  8.233   1.000 10.426 0 255  GLU A CG   1 ? 
ATOM   3833 C CD   . GLU A 1 240 ? -21.833 -8.164  8.900   1.000 11.256 0 255  GLU A CD   1 ? 
ATOM   3834 O OE1  . GLU A 1 240 ? -21.086 -8.947  8.258   1.000 10.908 0 255  GLU A OE1  1 ? 
ATOM   3835 O OE2  . GLU A 1 240 ? -22.063 -8.337  10.151  1.000 11.101 0 255  GLU A OE2  1 ? 
ATOM   3836 H H    . GLU A 1 240 ? -22.114 -8.981  6.411   1.000 10.234 0 255  GLU A H    1 c 
ATOM   3837 H HA   . GLU A 1 240 ? -23.459 -6.805  5.571   1.000 10.104 0 255  GLU A HA   1 c 
ATOM   3838 H HB2  . GLU A 1 240 ? -20.942 -6.782  6.916   1.000 10.329 0 255  GLU A HB2  1 c 
ATOM   3839 H HB3  . GLU A 1 240 ? -21.951 -5.568  6.862   1.000 10.323 0 255  GLU A HB3  1 c 
ATOM   3840 H HG2  . GLU A 1 240 ? -22.486 -6.221  8.855   1.000 10.647 0 255  GLU A HG2  1 c 
ATOM   3841 H HG3  . GLU A 1 240 ? -23.451 -7.205  8.084   1.000 10.647 0 255  GLU A HG3  1 c 
ATOM   3842 N N    . LEU A 1 241 ? -20.563 -7.283  4.164   1.000 10.106 0 256  LEU A N    1 ? 
ATOM   3843 C CA   . LEU A 1 241 ? -19.750 -6.914  3.000   1.000 10.102 0 256  LEU A CA   1 ? 
ATOM   3844 C C    . LEU A 1 241 ? -20.376 -7.418  1.700   1.000 10.915 0 256  LEU A C    1 ? 
ATOM   3845 O O    . LEU A 1 241 ? -20.280 -6.714  0.677   1.000 10.939 0 256  LEU A O    1 ? 
ATOM   3846 C CB   . LEU A 1 241 ? -18.339 -7.441  3.141   1.000 10.070 0 256  LEU A CB   1 ? 
ATOM   3847 C CG   . LEU A 1 241 ? -17.540 -6.680  4.204   1.000 9.270  0 256  LEU A CG   1 ? 
ATOM   3848 C CD1  . LEU A 1 241 ? -16.229 -7.419  4.445   1.000 9.613  0 256  LEU A CD1  1 ? 
ATOM   3849 C CD2  . LEU A 1 241 ? -17.284 -5.212  3.809   1.000 9.319  0 256  LEU A CD2  1 ? 
ATOM   3850 H H    . LEU A 1 241 ? -20.249 -7.915  4.745   1.000 10.242 0 256  LEU A H    1 c 
ATOM   3851 H HA   . LEU A 1 241 ? -19.719 -5.926  2.954   1.000 10.236 0 256  LEU A HA   1 c 
ATOM   3852 H HB2  . LEU A 1 241 ? -18.381 -8.392  3.393   1.000 9.890  0 256  LEU A HB2  1 c 
ATOM   3853 H HB3  . LEU A 1 241 ? -17.880 -7.351  2.274   1.000 9.896  0 256  LEU A HB3  1 c 
ATOM   3854 H HG   . LEU A 1 241 ? -18.060 -6.688  5.048   1.000 9.489  0 256  LEU A HG   1 c 
ATOM   3855 H HD11 . LEU A 1 241 ? -16.415 -8.331  4.722   1.000 9.520  0 256  LEU A HD11 1 c 
ATOM   3856 H HD12 . LEU A 1 241 ? -15.724 -6.967  5.142   1.000 9.506  0 256  LEU A HD12 1 c 
ATOM   3857 H HD13 . LEU A 1 241 ? -15.707 -7.431  3.625   1.000 9.512  0 256  LEU A HD13 1 c 
ATOM   3858 H HD21 . LEU A 1 241 ? -18.121 -4.719  3.824   1.000 9.314  0 256  LEU A HD21 1 c 
ATOM   3859 H HD22 . LEU A 1 241 ? -16.904 -5.177  2.915   1.000 9.306  0 256  LEU A HD22 1 c 
ATOM   3860 H HD23 . LEU A 1 241 ? -16.663 -4.810  4.439   1.000 9.301  0 256  LEU A HD23 1 c 
ATOM   3861 N N    . LEU A 1 242 ? -21.042 -8.584  1.709   1.000 10.400 0 257  LEU A N    1 ? 
ATOM   3862 C CA   . LEU A 1 242 ? -21.767 -9.050  0.527   1.000 9.812  0 257  LEU A CA   1 ? 
ATOM   3863 C C    . LEU A 1 242 ? -22.840 -8.030  0.165   1.000 9.994  0 257  LEU A C    1 ? 
ATOM   3864 O O    . LEU A 1 242 ? -22.985 -7.652  -1.005  1.000 10.784 0 257  LEU A O    1 ? 
ATOM   3865 C CB   . LEU A 1 242 ? -22.375 -10.428 0.778   1.000 10.632 0 257  LEU A CB   1 ? 
ATOM   3866 C CG   . LEU A 1 242 ? -21.385 -11.580 0.755   1.000 11.243 0 257  LEU A CG   1 ? 
ATOM   3867 C CD1  . LEU A 1 242 ? -22.039 -12.825 1.394   1.000 13.618 0 257  LEU A CD1  1 ? 
ATOM   3868 C CD2  . LEU A 1 242 ? -20.903 -11.884 -0.603  1.000 12.480 0 257  LEU A CD2  1 ? 
ATOM   3869 H H    . LEU A 1 242 ? -21.041 -9.103  2.462   1.000 10.385 0 257  LEU A H    1 c 
ATOM   3870 H HA   . LEU A 1 242 ? -21.125 -9.109  -0.225  1.000 10.130 0 257  LEU A HA   1 c 
ATOM   3871 H HB2  . LEU A 1 242 ? -22.820 -10.414 1.656   1.000 10.600 0 257  LEU A HB2  1 c 
ATOM   3872 H HB3  . LEU A 1 242 ? -23.061 -10.593 0.091   1.000 10.576 0 257  LEU A HB3  1 c 
ATOM   3873 H HG   . LEU A 1 242 ? -20.603 -11.326 1.309   1.000 11.756 0 257  LEU A HG   1 c 
ATOM   3874 H HD11 . LEU A 1 242 ? -22.247 -12.642 2.326   1.000 12.875 0 257  LEU A HD11 1 c 
ATOM   3875 H HD12 . LEU A 1 242 ? -21.425 -13.577 1.342   1.000 12.888 0 257  LEU A HD12 1 c 
ATOM   3876 H HD13 . LEU A 1 242 ? -22.858 -13.043 0.918   1.000 12.932 0 257  LEU A HD13 1 c 
ATOM   3877 H HD21 . LEU A 1 242 ? -20.425 -11.117 -0.960  1.000 12.080 0 257  LEU A HD21 1 c 
ATOM   3878 H HD22 . LEU A 1 242 ? -21.659 -12.090 -1.178  1.000 12.088 0 257  LEU A HD22 1 c 
ATOM   3879 H HD23 . LEU A 1 242 ? -20.305 -12.650 -0.571  1.000 12.088 0 257  LEU A HD23 1 c 
ATOM   3880 N N    . GLN A 1 243 ? -23.646 -7.611  1.150   1.000 10.373 0 258  GLN A N    1 ? 
ATOM   3881 C CA   . GLN A 1 243 ? -24.689 -6.620  0.911   1.000 10.691 0 258  GLN A CA   1 ? 
ATOM   3882 C C    . GLN A 1 243 ? -24.129 -5.299  0.394   1.000 10.687 0 258  GLN A C    1 ? 
ATOM   3883 O O    . GLN A 1 243 ? -24.684 -4.697  -0.537  1.000 11.119 0 258  GLN A O    1 ? 
ATOM   3884 C CB   . GLN A 1 243 ? -25.550 -6.399  2.150   1.000 12.346 0 258  GLN A CB   1 ? 
ATOM   3885 C CG   . GLN A 1 243 ? -26.678 -5.402  1.940   1.000 14.350 0 258  GLN A CG   1 ? 
ATOM   3886 C CD   . GLN A 1 243 ? -27.436 -5.037  3.200   1.000 15.605 0 258  GLN A CD   1 ? 
ATOM   3887 O OE1  . GLN A 1 243 ? -27.710 -3.867  3.460   1.000 17.893 0 258  GLN A OE1  1 ? 
ATOM   3888 N NE2  . GLN A 1 243 ? -27.708 -6.012  4.046   1.000 19.907 0 258  GLN A NE2  1 ? 
ATOM   3889 H H    . GLN A 1 243 ? -23.547 -7.954  1.991   1.000 10.360 0 258  GLN A H    1 c 
ATOM   3890 H HA   . GLN A 1 243 ? -25.286 -6.983  0.209   1.000 10.916 0 258  GLN A HA   1 c 
ATOM   3891 H HB2  . GLN A 1 243 ? -25.932 -7.259  2.424   1.000 12.396 0 258  GLN A HB2  1 c 
ATOM   3892 H HB3  . GLN A 1 243 ? -24.977 -6.083  2.879   1.000 12.371 0 258  GLN A HB3  1 c 
ATOM   3893 H HG2  . GLN A 1 243 ? -26.313 -4.577  1.557   1.000 14.128 0 258  GLN A HG2  1 c 
ATOM   3894 H HG3  . GLN A 1 243 ? -27.315 -5.771  1.292   1.000 14.177 0 258  GLN A HG3  1 c 
ATOM   3895 H HE21 . GLN A 1 243 ? -27.930 -6.814  3.740   1.000 18.425 0 258  GLN A HE21 1 c 
ATOM   3896 H HE22 . GLN A 1 243 ? -27.669 -5.863  4.920   1.000 18.457 0 258  GLN A HE22 1 c 
ATOM   3897 N N    . LEU A 1 244 ? -23.016 -4.819  0.993   1.000 10.169 0 259  LEU A N    1 ? 
ATOM   3898 C CA   . LEU A 1 244 ? -22.384 -3.573  0.574   1.000 9.113  0 259  LEU A CA   1 ? 
ATOM   3899 C C    . LEU A 1 244 ? -21.942 -3.659  -0.880  1.000 9.563  0 259  LEU A C    1 ? 
ATOM   3900 O O    . LEU A 1 244 ? -22.236 -2.774  -1.672  1.000 10.006 0 259  LEU A O    1 ? 
ATOM   3901 C CB   . LEU A 1 244 ? -21.210 -3.254  1.481   1.000 9.249  0 259  LEU A CB   1 ? 
ATOM   3902 C CG   . LEU A 1 244 ? -20.501 -1.943  1.169   1.000 9.779  0 259  LEU A CG   1 ? 
ATOM   3903 C CD1  . LEU A 1 244 ? -21.335 -0.705  1.181   1.000 10.093 0 259  LEU A CD1  1 ? 
ATOM   3904 C CD2  . LEU A 1 244 ? -19.309 -1.799  2.090   1.000 10.469 0 259  LEU A CD2  1 ? 
ATOM   3905 H H    . LEU A 1 244 ? -22.647 -5.286  1.687   1.000 10.040 0 259  LEU A H    1 c 
ATOM   3906 H HA   . LEU A 1 244 ? -23.056 -2.850  0.652   1.000 9.428  0 259  LEU A HA   1 c 
ATOM   3907 H HB2  . LEU A 1 244 ? -21.536 -3.221  2.409   1.000 9.335  0 259  LEU A HB2  1 c 
ATOM   3908 H HB3  . LEU A 1 244 ? -20.556 -3.988  1.411   1.000 9.335  0 259  LEU A HB3  1 c 
ATOM   3909 H HG   . LEU A 1 244 ? -20.133 -2.021  0.252   1.000 9.862  0 259  LEU A HG   1 c 
ATOM   3910 H HD11 . LEU A 1 244 ? -22.007 -0.758  0.482   1.000 9.990  0 259  LEU A HD11 1 c 
ATOM   3911 H HD12 . LEU A 1 244 ? -20.769 0.070   1.025   1.000 9.998  0 259  LEU A HD12 1 c 
ATOM   3912 H HD13 . LEU A 1 244 ? -21.773 -0.616  2.045   1.000 9.996  0 259  LEU A HD13 1 c 
ATOM   3913 H HD21 . LEU A 1 244 ? -18.708 -2.552  1.964   1.000 10.259 0 259  LEU A HD21 1 c 
ATOM   3914 H HD22 . LEU A 1 244 ? -19.613 -1.779  3.014   1.000 10.259 0 259  LEU A HD22 1 c 
ATOM   3915 H HD23 . LEU A 1 244 ? -18.839 -0.973  1.887   1.000 10.258 0 259  LEU A HD23 1 c 
ATOM   3916 N N    . GLN A 1 245 ? -21.243 -4.733  -1.216  1.000 8.667  0 260  GLN A N    1 ? 
ATOM   3917 C CA   . GLN A 1 245 ? -20.742 -4.886  -2.577  1.000 8.680  0 260  GLN A CA   1 ? 
ATOM   3918 C C    . GLN A 1 245 ? -21.906 -4.934  -3.579  1.000 9.400  0 260  GLN A C    1 ? 
ATOM   3919 O O    . GLN A 1 245 ? -21.859 -4.309  -4.639  1.000 9.103  0 260  GLN A O    1 ? 
ATOM   3920 C CB   . GLN A 1 245 ? -19.868 -6.127  -2.663  1.000 8.830  0 260  GLN A CB   1 ? 
ATOM   3921 C CG   . GLN A 1 245 ? -19.247 -6.325  -4.032  1.000 9.106  0 260  GLN A CG   1 ? 
ATOM   3922 C CD   . GLN A 1 245 ? -18.390 -7.550  -4.127  1.000 9.621  0 260  GLN A CD   1 ? 
ATOM   3923 O OE1  . GLN A 1 245 ? -18.885 -8.686  -3.976  1.000 13.342 0 260  GLN A OE1  1 ? 
ATOM   3924 N NE2  . GLN A 1 245 ? -17.111 -7.418  -4.398  1.000 9.692  0 260  GLN A NE2  1 ? 
ATOM   3925 H H    . GLN A 1 245 ? -21.066 -5.382  -0.597  1.000 8.886  0 260  GLN A H    1 c 
ATOM   3926 H HA   . GLN A 1 245 ? -20.181 -4.096  -2.789  1.000 8.841  0 260  GLN A HA   1 c 
ATOM   3927 H HB2  . GLN A 1 245 ? -19.155 -6.059  -1.995  1.000 8.858  0 260  GLN A HB2  1 c 
ATOM   3928 H HB3  . GLN A 1 245 ? -20.412 -6.912  -2.442  1.000 8.858  0 260  GLN A HB3  1 c 
ATOM   3929 H HG2  . GLN A 1 245 ? -19.959 -6.393  -4.703  1.000 9.162  0 260  GLN A HG2  1 c 
ATOM   3930 H HG3  . GLN A 1 245 ? -18.704 -5.540  -4.255  1.000 9.166  0 260  GLN A HG3  1 c 
ATOM   3931 H HE21 . GLN A 1 245 ? -16.753 -6.611  -4.488  1.000 9.657  0 260  GLN A HE21 1 c 
ATOM   3932 H HE22 . GLN A 1 245 ? -16.603 -8.140  -4.492  1.000 9.691  0 260  GLN A HE22 1 c 
ATOM   3933 N N    . GLN A 1 246 ? -22.967 -5.685  -3.209  1.000 8.895  0 261  GLN A N    1 ? 
ATOM   3934 C CA   . GLN A 1 246 ? -24.130 -5.848  -4.068  1.000 8.521  0 261  GLN A CA   1 ? 
ATOM   3935 C C    . GLN A 1 246 ? -24.795 -4.497  -4.284  1.000 7.949  0 261  GLN A C    1 ? 
ATOM   3936 O O    . GLN A 1 246 ? -25.121 -4.111  -5.433  1.000 9.227  0 261  GLN A O    1 ? 
ATOM   3937 C CB   . GLN A 1 246 ? -25.015 -6.897  -3.406  1.000 10.050 0 261  GLN A CB   1 ? 
ATOM   3938 C CG   . GLN A 1 246 ? -26.170 -7.389  -4.274  1.000 10.993 0 261  GLN A CG   1 ? 
ATOM   3939 C CD   . GLN A 1 246 ? -26.757 -8.629  -3.653  1.000 12.474 0 261  GLN A CD   1 ? 
ATOM   3940 O OE1  . GLN A 1 246 ? -26.463 -8.962  -2.486  1.000 15.294 0 261  GLN A OE1  1 ? 
ATOM   3941 N NE2  . GLN A 1 246 ? -27.589 -9.313  -4.414  1.000 12.632 0 261  GLN A NE2  1 ? 
ATOM   3942 H H    . GLN A 1 246 ? -22.956 -6.107  -2.399  1.000 8.938  0 261  GLN A H    1 c 
ATOM   3943 H HA   . GLN A 1 246 ? -23.823 -6.194  -4.944  1.000 8.744  0 261  GLN A HA   1 c 
ATOM   3944 H HB2  . GLN A 1 246 ? -24.454 -7.663  -3.163  1.000 9.911  0 261  GLN A HB2  1 c 
ATOM   3945 H HB3  . GLN A 1 246 ? -25.379 -6.521  -2.577  1.000 9.905  0 261  GLN A HB3  1 c 
ATOM   3946 H HG2  . GLN A 1 246 ? -26.858 -6.693  -4.341  1.000 11.092 0 261  GLN A HG2  1 c 
ATOM   3947 H HG3  . GLN A 1 246 ? -25.846 -7.591  -5.178  1.000 11.099 0 261  GLN A HG3  1 c 
ATOM   3948 H HE21 . GLN A 1 246 ? -27.700 -9.088  -5.264  1.000 12.564 0 261  GLN A HE21 1 c 
ATOM   3949 H HE22 . GLN A 1 246 ? -28.036 -10.000 -4.073  1.000 12.596 0 261  GLN A HE22 1 c 
ATOM   3950 N N    . LYS A 1 247 ? -25.056 -3.742  -3.204  1.000 8.563  0 262  LYS A N    1 ? 
ATOM   3951 C CA   . LYS A 1 247 ? -25.676 -2.439  -3.346  1.000 9.252  0 262  LYS A CA   1 ? 
ATOM   3952 C C    . LYS A 1 247 ? -24.847 -1.430  -4.141  1.000 9.132  0 262  LYS A C    1 ? 
ATOM   3953 O O    . LYS A 1 247 ? -25.369 -0.649  -4.954  1.000 9.691  0 262  LYS A O    1 ? 
ATOM   3954 C CB   . LYS A 1 247 ? -26.053 -1.809  -1.997  1.000 10.130 0 262  LYS A CB   1 ? 
ATOM   3955 C CG   . LYS A 1 247 ? -27.251 -2.514  -1.327  1.000 9.962  0 262  LYS A CG   1 ? 
ATOM   3956 C CD   . LYS A 1 247 ? -27.545 -1.913  0.043   1.000 11.830 0 262  LYS A CD   1 ? 
ATOM   3957 C CE   . LYS A 1 247 ? -28.879 -2.417  0.556   1.000 12.886 0 262  LYS A CE   1 ? 
ATOM   3958 N NZ   . LYS A 1 247 ? -29.147 -2.012  1.963   1.000 14.077 0 262  LYS A NZ   1 ? 
ATOM   3959 H H    . LYS A 1 247 ? -24.847 -4.049  -2.368  1.000 8.571  0 262  LYS A H    1 c 
ATOM   3960 H HA   . LYS A 1 247 ? -26.526 -2.571  -3.838  1.000 9.239  0 262  LYS A HA   1 c 
ATOM   3961 H HB2  . LYS A 1 247 ? -25.282 -1.853  -1.393  1.000 9.886  0 262  LYS A HB2  1 c 
ATOM   3962 H HB3  . LYS A 1 247 ? -26.280 -0.864  -2.132  1.000 9.883  0 262  LYS A HB3  1 c 
ATOM   3963 H HG2  . LYS A 1 247 ? -28.041 -2.421  -1.903  1.000 10.410 0 262  LYS A HG2  1 c 
ATOM   3964 H HG3  . LYS A 1 247 ? -27.047 -3.470  -1.229  1.000 10.401 0 262  LYS A HG3  1 c 
ATOM   3965 H HD2  . LYS A 1 247 ? -26.837 -2.167  0.674   1.000 11.603 0 262  LYS A HD2  1 c 
ATOM   3966 H HD3  . LYS A 1 247 ? -27.572 -0.933  -0.026  1.000 11.603 0 262  LYS A HD3  1 c 
ATOM   3967 H HE2  . LYS A 1 247 ? -29.592 -2.071  -0.011  1.000 12.902 0 262  LYS A HE2  1 c 
ATOM   3968 H HE3  . LYS A 1 247 ? -28.897 -3.389  0.500   1.000 12.902 0 262  LYS A HE3  1 c 
ATOM   3969 H HZ1  . LYS A 1 247 ? -29.209 -1.111  2.015   1.000 13.708 0 262  LYS A HZ1  1 c 
ATOM   3970 H HZ2  . LYS A 1 247 ? -28.473 -2.297  2.498   1.000 13.701 0 262  LYS A HZ2  1 c 
ATOM   3971 H HZ3  . LYS A 1 247 ? -29.926 -2.380  2.245   1.000 13.701 0 262  LYS A HZ3  1 c 
ATOM   3972 N N    . LEU A 1 248 ? -23.531 -1.469  -3.939  1.000 8.877  0 263  LEU A N    1 ? 
ATOM   3973 C CA   . LEU A 1 248 ? -22.646 -0.605  -4.690  1.000 8.386  0 263  LEU A CA   1 ? 
ATOM   3974 C C    . LEU A 1 248 ? -22.623 -0.948  -6.185  1.000 8.769  0 263  LEU A C    1 ? 
ATOM   3975 O O    . LEU A 1 248 ? -22.614 -0.054  -7.038  1.000 8.475  0 263  LEU A O    1 ? 
ATOM   3976 C CB   . LEU A 1 248 ? -21.240 -0.547  -4.098  1.000 8.215  0 263  LEU A CB   1 ? 
ATOM   3977 C CG   . LEU A 1 248 ? -21.119 0.138   -2.739  1.000 8.410  0 263  LEU A CG   1 ? 
ATOM   3978 C CD1  . LEU A 1 248 ? -19.738 -0.038  -2.157  1.000 9.218  0 263  LEU A CD1  1 ? 
ATOM   3979 C CD2  . LEU A 1 248 ? -21.441 1.634   -2.800  1.000 9.022  0 263  LEU A CD2  1 ? 
ATOM   3980 H H    . LEU A 1 248 ? -23.177 -2.039  -3.319  1.000 8.820  0 263  LEU A H    1 c 
ATOM   3981 H HA   . LEU A 1 248 ? -23.029 0.306   -4.628  1.000 8.531  0 263  LEU A HA   1 c 
ATOM   3982 H HB2  . LEU A 1 248 ? -20.905 -1.469  -4.012  1.000 8.298  0 263  LEU A HB2  1 c 
ATOM   3983 H HB3  . LEU A 1 248 ? -20.657 -0.075  -4.736  1.000 8.300  0 263  LEU A HB3  1 c 
ATOM   3984 H HG   . LEU A 1 248 ? -21.768 -0.287  -2.121  1.000 8.637  0 263  LEU A HG   1 c 
ATOM   3985 H HD11 . LEU A 1 248 ? -19.544 -0.986  -2.062  1.000 8.969  0 263  LEU A HD11 1 c 
ATOM   3986 H HD12 . LEU A 1 248 ? -19.696 0.389   -1.285  1.000 8.969  0 263  LEU A HD12 1 c 
ATOM   3987 H HD13 . LEU A 1 248 ? -19.082 0.368   -2.748  1.000 8.969  0 263  LEU A HD13 1 c 
ATOM   3988 H HD21 . LEU A 1 248 ? -22.387 1.757   -2.988  1.000 8.837  0 263  LEU A HD21 1 c 
ATOM   3989 H HD22 . LEU A 1 248 ? -20.915 2.051   -3.503  1.000 8.840  0 263  LEU A HD22 1 c 
ATOM   3990 H HD23 . LEU A 1 248 ? -21.226 2.048   -1.947  1.000 8.841  0 263  LEU A HD23 1 c 
ATOM   3991 N N    . LEU A 1 249 ? -22.586 -2.242  -6.499  1.000 8.211  0 264  LEU A N    1 ? 
ATOM   3992 C CA   . LEU A 1 249 ? -22.650 -2.652  -7.911  1.000 8.409  0 264  LEU A CA   1 ? 
ATOM   3993 C C    . LEU A 1 249 ? -24.000 -2.251  -8.523  1.000 8.392  0 264  LEU A C    1 ? 
ATOM   3994 O O    . LEU A 1 249 ? -23.973 -1.804  -9.686  1.000 8.819  0 264  LEU A O    1 ? 
ATOM   3995 C CB   . LEU A 1 249 ? -22.374 -4.151  -8.013  1.000 8.910  0 264  LEU A CB   1 ? 
ATOM   3996 C CG   . LEU A 1 249 ? -20.907 -4.559  -7.821  1.000 9.278  0 264  LEU A CG   1 ? 
ATOM   3997 C CD1  . LEU A 1 249 ? -20.869 -6.055  -7.870  1.000 10.010 0 264  LEU A CD1  1 ? 
ATOM   3998 C CD2  . LEU A 1 249 ? -20.010 -4.019  -8.912  1.000 10.216 0 264  LEU A CD2  1 ? 
ATOM   3999 H H    . LEU A 1 249 ? -22.516 -2.878  -5.846  1.000 8.396  0 264  LEU A H    1 c 
ATOM   4000 H HA   . LEU A 1 249 ? -21.940 -2.164  -8.400  1.000 8.477  0 264  LEU A HA   1 c 
ATOM   4001 H HB2  . LEU A 1 249 ? -22.920 -4.612  -7.335  1.000 8.882  0 264  LEU A HB2  1 c 
ATOM   4002 H HB3  . LEU A 1 249 ? -22.670 -4.459  -8.901  1.000 8.873  0 264  LEU A HB3  1 c 
ATOM   4003 H HG   . LEU A 1 249 ? -20.590 -4.244  -6.937  1.000 9.501  0 264  LEU A HG   1 c 
ATOM   4004 H HD11 . LEU A 1 249 ? -21.412 -6.418  -7.150  1.000 9.778  0 264  LEU A HD11 1 c 
ATOM   4005 H HD12 . LEU A 1 249 ? -19.952 -6.360  -7.767  1.000 9.783  0 264  LEU A HD12 1 c 
ATOM   4006 H HD13 . LEU A 1 249 ? -21.218 -6.362  -8.723  1.000 9.779  0 264  LEU A HD13 1 c 
ATOM   4007 H HD21 . LEU A 1 249 ? -19.936 -3.054  -8.825  1.000 9.909  0 264  LEU A HD21 1 c 
ATOM   4008 H HD22 . LEU A 1 249 ? -20.388 -4.238  -9.781  1.000 9.924  0 264  LEU A HD22 1 c 
ATOM   4009 H HD23 . LEU A 1 249 ? -19.127 -4.419  -8.835  1.000 9.923  0 264  LEU A HD23 1 c 
ATOM   4010 N N    . TRP A 1 250 ? -25.124 -2.305  -7.792  1.000 8.644  0 265  TRP A N    1 ? 
ATOM   4011 C CA   . TRP A 1 250 ? -26.374 -1.847  -8.403  1.000 9.111  0 265  TRP A CA   1 ? 
ATOM   4012 C C    . TRP A 1 250 ? -26.344 -0.333  -8.639  1.000 9.518  0 265  TRP A C    1 ? 
ATOM   4013 O O    . TRP A 1 250 ? -26.902 0.151   -9.626  1.000 10.151 0 265  TRP A O    1 ? 
ATOM   4014 C CB   . TRP A 1 250 ? -27.605 -2.237  -7.572  1.000 8.820  0 265  TRP A CB   1 ? 
ATOM   4015 C CG   . TRP A 1 250 ? -28.035 -3.653  -7.824  1.000 9.449  0 265  TRP A CG   1 ? 
ATOM   4016 C CD1  . TRP A 1 250 ? -28.092 -4.669  -6.932  1.000 9.684  0 265  TRP A CD1  1 ? 
ATOM   4017 C CD2  . TRP A 1 250 ? -28.398 -4.237  -9.110  1.000 9.191  0 265  TRP A CD2  1 ? 
ATOM   4018 N NE1  . TRP A 1 250 ? -28.512 -5.834  -7.533  1.000 10.311 0 265  TRP A NE1  1 ? 
ATOM   4019 C CE2  . TRP A 1 250 ? -28.687 -5.585  -8.864  1.000 9.612  0 265  TRP A CE2  1 ? 
ATOM   4020 C CE3  . TRP A 1 250 ? -28.526 -3.714  -10.398 1.000 11.103 0 265  TRP A CE3  1 ? 
ATOM   4021 C CZ2  . TRP A 1 250 ? -29.069 -6.424  -9.907  1.000 10.982 0 265  TRP A CZ2  1 ? 
ATOM   4022 C CZ3  . TRP A 1 250 ? -28.894 -4.575  -11.413 1.000 9.901  0 265  TRP A CZ3  1 ? 
ATOM   4023 C CH2  . TRP A 1 250 ? -29.110 -5.917  -11.168 1.000 11.012 0 265  TRP A CH2  1 ? 
ATOM   4024 H H    . TRP A 1 250 ? -25.121 -2.623  -6.936  1.000 8.684  0 265  TRP A H    1 c 
ATOM   4025 H HA   . TRP A 1 250 ? -26.454 -2.290  -9.289  1.000 9.051  0 265  TRP A HA   1 c 
ATOM   4026 H HB2  . TRP A 1 250 ? -27.390 -2.131  -6.621  1.000 9.030  0 265  TRP A HB2  1 c 
ATOM   4027 H HB3  . TRP A 1 250 ? -28.343 -1.633  -7.798  1.000 9.053  0 265  TRP A HB3  1 c 
ATOM   4028 H HD1  . TRP A 1 250 ? -27.906 -4.586  -6.010  1.000 9.766  0 265  TRP A HD1  1 c 
ATOM   4029 H HE1  . TRP A 1 250 ? -28.613 -6.605  -7.137  1.000 10.005 0 265  TRP A HE1  1 c 
ATOM   4030 H HE3  . TRP A 1 250 ? -28.328 -2.810  -10.575 1.000 10.342 0 265  TRP A HE3  1 c 
ATOM   4031 H HZ2  . TRP A 1 250 ? -29.235 -7.338  -9.749  1.000 10.645 0 265  TRP A HZ2  1 c 
ATOM   4032 H HZ3  . TRP A 1 250 ? -28.956 -4.250  -12.297 1.000 10.438 0 265  TRP A HZ3  1 c 
ATOM   4033 H HH2  . TRP A 1 250 ? -29.395 -6.471  -11.872 1.000 10.748 0 265  TRP A HH2  1 c 
ATOM   4034 N N    . LEU A 1 251 ? -25.750 0.429   -7.719  1.000 9.367  0 266  LEU A N    1 ? 
ATOM   4035 C CA   . LEU A 1 251 ? -25.615 1.869   -7.900  1.000 8.750  0 266  LEU A CA   1 ? 
ATOM   4036 C C    . LEU A 1 251 ? -24.844 2.149   -9.185  1.000 10.105 0 266  LEU A C    1 ? 
ATOM   4037 O O    . LEU A 1 251 ? -25.254 2.953   -10.034 1.000 10.192 0 266  LEU A O    1 ? 
ATOM   4038 C CB   . LEU A 1 251 ? -24.945 2.447   -6.658  1.000 9.798  0 266  LEU A CB   1 ? 
ATOM   4039 C CG   . LEU A 1 251 ? -24.516 3.907   -6.754  1.000 11.515 0 266  LEU A CG   1 ? 
ATOM   4040 C CD1  . LEU A 1 251 ? -25.694 4.831   -6.930  1.000 15.462 0 266  LEU A CD1  1 ? 
ATOM   4041 C CD2  . LEU A 1 251 ? -23.682 4.326   -5.565  1.000 12.018 0 266  LEU A CD2  1 ? 
ATOM   4042 H H    . LEU A 1 251 ? -25.426 0.046   -6.955  1.000 9.263  0 266  LEU A H    1 c 
ATOM   4043 H HA   . LEU A 1 251 ? -26.524 2.255   -7.988  1.000 9.324  0 266  LEU A HA   1 c 
ATOM   4044 H HB2  . LEU A 1 251 ? -25.570 2.355   -5.902  1.000 9.904  0 266  LEU A HB2  1 c 
ATOM   4045 H HB3  . LEU A 1 251 ? -24.150 1.903   -6.456  1.000 9.894  0 266  LEU A HB3  1 c 
ATOM   4046 H HG   . LEU A 1 251 ? -23.944 4.002   -7.558  1.000 11.904 0 266  LEU A HG   1 c 
ATOM   4047 H HD11 . LEU A 1 251 ? -26.209 4.552   -7.701  1.000 14.201 0 266  LEU A HD11 1 c 
ATOM   4048 H HD12 . LEU A 1 251 ? -25.378 5.740   -7.063  1.000 14.169 0 266  LEU A HD12 1 c 
ATOM   4049 H HD13 . LEU A 1 251 ? -26.256 4.796   -6.137  1.000 14.169 0 266  LEU A HD13 1 c 
ATOM   4050 H HD21 . LEU A 1 251 ? -22.882 3.776   -5.519  1.000 11.867 0 266  LEU A HD21 1 c 
ATOM   4051 H HD22 . LEU A 1 251 ? -24.198 4.213   -4.749  1.000 11.867 0 266  LEU A HD22 1 c 
ATOM   4052 H HD23 . LEU A 1 251 ? -23.427 5.259   -5.660  1.000 11.867 0 266  LEU A HD23 1 c 
ATOM   4053 N N    . LEU A 1 252 ? -23.671 1.526   -9.321  1.000 9.459  0 267  LEU A N    1 ? 
ATOM   4054 C CA   . LEU A 1 252 ? -22.854 1.659   -10.515 1.000 9.498  0 267  LEU A CA   1 ? 
ATOM   4055 C C    . LEU A 1 252 ? -23.630 1.208   -11.758 1.000 9.138  0 267  LEU A C    1 ? 
ATOM   4056 O O    . LEU A 1 252 ? -23.552 1.906   -12.804 1.000 10.289 0 267  LEU A O    1 ? 
ATOM   4057 C CB   . LEU A 1 252 ? -21.572 0.864   -10.345 1.000 8.812  0 267  LEU A CB   1 ? 
ATOM   4058 C CG   . LEU A 1 252 ? -20.587 1.475   -9.348  1.000 9.276  0 267  LEU A CG   1 ? 
ATOM   4059 C CD1  . LEU A 1 252 ? -19.675 0.354   -8.833  1.000 9.500  0 267  LEU A CD1  1 ? 
ATOM   4060 C CD2  . LEU A 1 252 ? -19.800 2.577   -9.992  1.000 10.122 0 267  LEU A CD2  1 ? 
ATOM   4061 H H    . LEU A 1 252 ? -23.365 1.001   -8.638  1.000 9.600  0 267  LEU A H    1 c 
ATOM   4062 H HA   . LEU A 1 252 ? -22.626 2.617   -10.624 1.000 9.306  0 267  LEU A HA   1 c 
ATOM   4063 H HB2  . LEU A 1 252 ? -21.806 -0.043  -10.042 1.000 9.080  0 267  LEU A HB2  1 c 
ATOM   4064 H HB3  . LEU A 1 252 ? -21.129 0.795   -11.222 1.000 9.082  0 267  LEU A HB3  1 c 
ATOM   4065 H HG   . LEU A 1 252 ? -21.098 1.849   -8.584  1.000 9.382  0 267  LEU A HG   1 c 
ATOM   4066 H HD11 . LEU A 1 252 ? -20.193 -0.262  -8.287  1.000 9.427  0 267  LEU A HD11 1 c 
ATOM   4067 H HD12 . LEU A 1 252 ? -18.960 0.737   -8.297  1.000 9.429  0 267  LEU A HD12 1 c 
ATOM   4068 H HD13 . LEU A 1 252 ? -19.293 -0.126  -9.587  1.000 9.417  0 267  LEU A HD13 1 c 
ATOM   4069 H HD21 . LEU A 1 252 ? -20.405 3.272   -10.300 1.000 9.856  0 267  LEU A HD21 1 c 
ATOM   4070 H HD22 . LEU A 1 252 ? -19.303 2.222   -10.748 1.000 9.854  0 267  LEU A HD22 1 c 
ATOM   4071 H HD23 . LEU A 1 252 ? -19.179 2.953   -9.345  1.000 9.859  0 267  LEU A HD23 1 c 
ATOM   4072 N N    . TYR A 1 253 ? -24.344 0.095   -11.687 1.000 9.084  0 268  TYR A N    1 ? 
ATOM   4073 C CA   . TYR A 1 253 ? -25.140 -0.374  -12.828 1.000 9.007  0 268  TYR A CA   1 ? 
ATOM   4074 C C    . TYR A 1 253 ? -26.132 0.699   -13.280 1.000 9.749  0 268  TYR A C    1 ? 
ATOM   4075 O O    . TYR A 1 253 ? -26.215 0.984   -14.478 1.000 10.264 0 268  TYR A O    1 ? 
ATOM   4076 C CB   . TYR A 1 253 ? -25.860 -1.632  -12.412 1.000 10.906 0 268  TYR A CB   1 ? 
ATOM   4077 C CG   . TYR A 1 253 ? -26.771 -2.233  -13.468 1.000 11.098 0 268  TYR A CG   1 ? 
ATOM   4078 C CD1  . TYR A 1 253 ? -28.076 -1.774  -13.643 1.000 12.059 0 268  TYR A CD1  1 ? 
ATOM   4079 C CD2  . TYR A 1 253 ? -26.371 -3.332  -14.217 1.000 14.910 0 268  TYR A CD2  1 ? 
ATOM   4080 C CE1  . TYR A 1 253 ? -28.973 -2.391  -14.503 1.000 15.029 0 268  TYR A CE1  1 ? 
ATOM   4081 C CE2  . TYR A 1 253 ? -27.260 -3.955  -15.086 1.000 16.450 0 268  TYR A CE2  1 ? 
ATOM   4082 C CZ   . TYR A 1 253 ? -28.551 -3.489  -15.213 1.000 17.618 0 268  TYR A CZ   1 ? 
ATOM   4083 O OH   . TYR A 1 253 ? -29.386 -4.149  -16.100 1.000 21.782 0 268  TYR A OH   1 ? 
ATOM   4084 H H    . TYR A 1 253 ? -24.340 -0.398  -10.917 1.000 9.096  0 268  TYR A H    1 c 
ATOM   4085 H HA   . TYR A 1 253 ? -24.527 -0.587  -13.581 1.000 9.490  0 268  TYR A HA   1 c 
ATOM   4086 H HB2  . TYR A 1 253 ? -25.189 -2.303  -12.157 1.000 10.490 0 268  TYR A HB2  1 c 
ATOM   4087 H HB3  . TYR A 1 253 ? -26.395 -1.432  -11.613 1.000 10.476 0 268  TYR A HB3  1 c 
ATOM   4088 H HD1  . TYR A 1 253 ? -28.379 -1.054  -13.114 1.000 12.518 0 268  TYR A HD1  1 c 
ATOM   4089 H HD2  . TYR A 1 253 ? -25.507 -3.692  -14.097 1.000 14.246 0 268  TYR A HD2  1 c 
ATOM   4090 H HE1  . TYR A 1 253 ? -29.852 -2.066  -14.599 1.000 14.880 0 268  TYR A HE1  1 c 
ATOM   4091 H HE2  . TYR A 1 253 ? -26.982 -4.705  -15.584 1.000 16.282 0 268  TYR A HE2  1 c 
ATOM   4092 H HH   . TYR A 1 253 ? -29.310 -3.806  -16.883 0.000 21.790 0 268  TYR A HH   1 c 
ATOM   4093 N N    . ASP A 1 254 ? -26.903 1.248   -12.332 1.000 10.430 0 269  ASP A N    1 ? 
ATOM   4094 C CA   . ASP A 1 254 ? -27.955 2.209   -12.640 1.000 11.082 0 269  ASP A CA   1 ? 
ATOM   4095 C C    . ASP A 1 254 ? -27.390 3.461   -13.281 1.000 12.600 0 269  ASP A C    1 ? 
ATOM   4096 O O    . ASP A 1 254 ? -28.093 4.099   -14.080 1.000 14.099 0 269  ASP A O    1 ? 
ATOM   4097 C CB   . ASP A 1 254 ? -28.757 2.536   -11.385 1.000 11.567 0 269  ASP A CB   1 ? 
ATOM   4098 C CG   . ASP A 1 254 ? -29.690 1.444   -10.924 1.000 13.599 0 269  ASP A CG   1 ? 
ATOM   4099 O OD1  . ASP A 1 254 ? -29.987 0.501   -11.721 1.000 13.601 0 269  ASP A OD1  1 ? 
ATOM   4100 O OD2  . ASP A 1 254 ? -30.145 1.544   -9.735  1.000 14.557 0 269  ASP A OD2  1 ? 
ATOM   4101 H H    . ASP A 1 254 ? -26.769 1.010   -11.460 1.000 10.404 0 269  ASP A H    1 c 
ATOM   4102 H HA   . ASP A 1 254 ? -28.569 1.789   -13.284 1.000 11.329 0 269  ASP A HA   1 c 
ATOM   4103 H HB2  . ASP A 1 254 ? -28.135 2.736   -10.654 1.000 11.884 0 269  ASP A HB2  1 c 
ATOM   4104 H HB3  . ASP A 1 254 ? -29.292 3.340   -11.552 1.000 11.896 0 269  ASP A HB3  1 c 
ATOM   4105 N N    . LEU A 1 255 ? -26.183 3.849   -12.916 1.000 10.939 0 270  LEU A N    1 ? 
ATOM   4106 C CA   . LEU A 1 255 ? -25.530 5.050   -13.436 1.000 11.085 0 270  LEU A CA   1 ? 
ATOM   4107 C C    . LEU A 1 255 ? -24.870 4.820   -14.785 1.000 11.888 0 270  LEU A C    1 ? 
ATOM   4108 O O    . LEU A 1 255 ? -24.362 5.762   -15.383 1.000 13.436 0 270  LEU A O    1 ? 
ATOM   4109 C CB   . LEU A 1 255 ? -24.512 5.583   -12.418 1.000 12.330 0 270  LEU A CB   1 ? 
ATOM   4110 C CG   . LEU A 1 255 ? -25.119 6.136   -11.136 1.000 13.829 0 270  LEU A CG   1 ? 
ATOM   4111 C CD1  . LEU A 1 255 ? -24.029 6.398   -10.116 1.000 14.245 0 270  LEU A CD1  1 ? 
ATOM   4112 C CD2  . LEU A 1 255 ? -25.897 7.433   -11.385 1.000 16.115 0 270  LEU A CD2  1 ? 
ATOM   4113 H H    . LEU A 1 255 ? -25.732 3.349   -12.298 1.000 11.344 0 270  LEU A H    1 c 
ATOM   4114 H HA   . LEU A 1 255 ? -26.230 5.738   -13.566 1.000 11.481 0 270  LEU A HA   1 c 
ATOM   4115 H HB2  . LEU A 1 255 ? -23.897 4.851   -12.183 1.000 12.359 0 270  LEU A HB2  1 c 
ATOM   4116 H HB3  . LEU A 1 255 ? -23.988 6.298   -12.848 1.000 12.360 0 270  LEU A HB3  1 c 
ATOM   4117 H HG   . LEU A 1 255 ? -25.740 5.459   -10.767 1.000 14.049 0 270  LEU A HG   1 c 
ATOM   4118 H HD11 . LEU A 1 255 ? -23.564 5.568   -9.917  1.000 14.121 0 270  LEU A HD11 1 c 
ATOM   4119 H HD12 . LEU A 1 255 ? -24.424 6.750   -9.301  1.000 14.121 0 270  LEU A HD12 1 c 
ATOM   4120 H HD13 . LEU A 1 255 ? -23.397 7.044   -10.474 1.000 14.121 0 270  LEU A HD13 1 c 
ATOM   4121 H HD21 . LEU A 1 255 ? -26.677 7.246   -11.935 1.000 15.350 0 270  LEU A HD21 1 c 
ATOM   4122 H HD22 . LEU A 1 255 ? -25.325 8.072   -11.843 1.000 15.394 0 270  LEU A HD22 1 c 
ATOM   4123 H HD23 . LEU A 1 255 ? -26.185 7.808   -10.535 1.000 15.394 0 270  LEU A HD23 1 c 
ATOM   4124 N N    . GLY A 1 256 ? -24.811 3.559   -15.235 1.000 10.644 0 271  GLY A N    1 ? 
ATOM   4125 C CA   . GLY A 1 256 ? -24.225 3.215   -16.508 1.000 11.183 0 271  GLY A CA   1 ? 
ATOM   4126 C C    . GLY A 1 256 ? -22.764 2.796   -16.421 1.000 10.471 0 271  GLY A C    1 ? 
ATOM   4127 O O    . GLY A 1 256 ? -22.137 2.568   -17.473 1.000 12.037 0 271  GLY A O    1 ? 
ATOM   4128 H H    . GLY A 1 256 ? -25.142 2.885   -14.716 1.000 11.051 0 271  GLY A H    1 c 
ATOM   4129 H HA2  . GLY A 1 256 ? -24.746 2.478   -16.904 1.000 10.894 0 271  GLY A HA2  1 c 
ATOM   4130 H HA3  . GLY A 1 256 ? -24.302 3.989   -17.115 1.000 10.909 0 271  GLY A HA3  1 c 
ATOM   4131 N N    . HIS A 1 257 ? -22.154 2.709   -15.233 1.000 10.238 0 272  HIS A N    1 ? 
ATOM   4132 C CA   . HIS A 1 257 ? -20.718 2.521   -15.116 1.000 9.806  0 272  HIS A CA   1 ? 
ATOM   4133 C C    . HIS A 1 257 ? -20.273 1.059   -15.172 1.000 10.141 0 272  HIS A C    1 ? 
ATOM   4134 O O    . HIS A 1 257 ? -19.059 0.849   -15.077 1.000 10.773 0 272  HIS A O    1 ? 
ATOM   4135 C CB   . HIS A 1 257 ? -20.206 3.226   -13.849 1.000 10.847 0 272  HIS A CB   1 ? 
ATOM   4136 C CG   . HIS A 1 257 ? -20.587 4.663   -13.851 1.000 12.311 0 272  HIS A CG   1 ? 
ATOM   4137 N ND1  . HIS A 1 257 ? -20.400 5.481   -14.949 1.000 14.505 0 272  HIS A ND1  1 ? 
ATOM   4138 C CD2  . HIS A 1 257 ? -21.162 5.412   -12.874 1.000 12.202 0 272  HIS A CD2  1 ? 
ATOM   4139 C CE1  . HIS A 1 257 ? -20.824 6.723   -14.612 1.000 14.861 0 272  HIS A CE1  1 ? 
ATOM   4140 N NE2  . HIS A 1 257 ? -21.256 6.715   -13.368 1.000 13.450 0 272  HIS A NE2  1 ? 
ATOM   4141 H H    . HIS A 1 257 ? -22.653 2.759   -14.469 1.000 10.210 0 272  HIS A H    1 c 
ATOM   4142 H HA   . HIS A 1 257 ? -20.306 2.986   -15.886 1.000 10.167 0 272  HIS A HA   1 c 
ATOM   4143 H HB2  . HIS A 1 257 ? -20.592 2.788   -13.059 1.000 10.923 0 272  HIS A HB2  1 c 
ATOM   4144 H HB3  . HIS A 1 257 ? -19.228 3.149   -13.812 1.000 10.922 0 272  HIS A HB3  1 c 
ATOM   4145 H HD1  . HIS A 1 257 ? -20.050 5.230   -15.719 0.000 14.510 0 272  HIS A HD1  1 c 
ATOM   4146 H HD2  . HIS A 1 257 ? -21.384 5.134   -12.008 1.000 12.510 0 272  HIS A HD2  1 c 
ATOM   4147 H HE1  . HIS A 1 257 ? -20.804 7.473   -15.182 1.000 14.402 0 272  HIS A HE1  1 c 
ATOM   4148 H HE2  . HIS A 1 257 ? -21.577 7.407   -12.936 0.000 13.460 0 272  HIS A HE2  1 c 
ATOM   4149 N N    . LEU A 1 258 ? -21.205 0.110   -15.326 1.000 9.081  0 273  LEU A N    1 ? 
ATOM   4150 C CA   . LEU A 1 258 ? -20.798 -1.272  -15.570 1.000 9.334  0 273  LEU A CA   1 ? 
ATOM   4151 C C    . LEU A 1 258 ? -20.886 -1.648  -17.059 1.000 9.913  0 273  LEU A C    1 ? 
ATOM   4152 O O    . LEU A 1 258 ? -20.603 -2.807  -17.403 1.000 8.958  0 273  LEU A O    1 ? 
ATOM   4153 C CB   . LEU A 1 258 ? -21.592 -2.261  -14.734 1.000 8.489  0 273  LEU A CB   1 ? 
ATOM   4154 C CG   . LEU A 1 258 ? -21.544 -2.047  -13.220 1.000 8.782  0 273  LEU A CG   1 ? 
ATOM   4155 C CD1  . LEU A 1 258 ? -22.235 -3.202  -12.514 1.000 10.061 0 273  LEU A CD1  1 ? 
ATOM   4156 C CD2  . LEU A 1 258 ? -20.128 -1.885  -12.699 1.000 8.837  0 273  LEU A CD2  1 ? 
ATOM   4157 H H    . LEU A 1 258 ? -22.094 0.314   -15.268 1.000 9.390  0 273  LEU A H    1 c 
ATOM   4158 H HA   . LEU A 1 258 ? -19.845 -1.350  -15.312 1.000 9.234  0 273  LEU A HA   1 c 
ATOM   4159 H HB2  . LEU A 1 258 ? -22.532 -2.222  -15.024 1.000 8.745  0 273  LEU A HB2  1 c 
ATOM   4160 H HB3  . LEU A 1 258 ? -21.257 -3.167  -14.929 1.000 8.750  0 273  LEU A HB3  1 c 
ATOM   4161 H HG   . LEU A 1 258 ? -22.044 -1.217  -13.010 1.000 8.962  0 273  LEU A HG   1 c 
ATOM   4162 H HD11 . LEU A 1 258 ? -23.148 -3.280  -12.837 1.000 9.669  0 273  LEU A HD11 1 c 
ATOM   4163 H HD12 . LEU A 1 258 ? -22.244 -3.039  -11.556 1.000 9.660  0 273  LEU A HD12 1 c 
ATOM   4164 H HD13 . LEU A 1 258 ? -21.757 -4.028  -12.697 1.000 9.664  0 273  LEU A HD13 1 c 
ATOM   4165 H HD21 . LEU A 1 258 ? -19.777 -1.021  -12.973 1.000 8.828  0 273  LEU A HD21 1 c 
ATOM   4166 H HD22 . LEU A 1 258 ? -19.566 -2.591  -13.059 1.000 8.820  0 273  LEU A HD22 1 c 
ATOM   4167 H HD23 . LEU A 1 258 ? -20.131 -1.938  -11.728 1.000 8.833  0 273  LEU A HD23 1 c 
ATOM   4168 N N    A GLU A 1 259 ? -21.321 -0.697  -17.890 0.500 8.704  0 274  GLU A N    1 ? 
ATOM   4169 N N    B GLU A 1 259 ? -21.336 -0.751  -17.931 0.500 9.628  0 274  GLU A N    1 ? 
ATOM   4170 C CA   A GLU A 1 259 ? -21.561 -0.901  -19.314 0.500 8.746  0 274  GLU A CA   1 ? 
ATOM   4171 C CA   B GLU A 1 259 ? -21.599 -1.121  -19.319 0.500 10.261 0 274  GLU A CA   1 ? 
ATOM   4172 C C    A GLU A 1 259 ? -20.400 -1.620  -19.983 0.500 8.413  0 274  GLU A C    1 ? 
ATOM   4173 C C    B GLU A 1 259 ? -20.355 -1.612  -20.057 0.500 9.278  0 274  GLU A C    1 ? 
ATOM   4174 O O    A GLU A 1 259 ? -20.668 -2.553  -20.760 0.500 8.024  0 274  GLU A O    1 ? 
ATOM   4175 O O    B GLU A 1 259 ? -20.466 -2.360  -21.017 0.500 8.970  0 274  GLU A O    1 ? 
ATOM   4176 C CB   A GLU A 1 259 ? -21.808 0.448   -19.999 0.500 8.922  0 274  GLU A CB   1 ? 
ATOM   4177 C CB   B GLU A 1 259 ? -22.119 0.087   -20.095 0.500 12.335 0 274  GLU A CB   1 ? 
ATOM   4178 C CG   A GLU A 1 259 ? -22.068 0.330   -21.506 0.500 8.136  0 274  GLU A CG   1 ? 
ATOM   4179 C CG   B GLU A 1 259 ? -23.518 0.518   -19.689 0.500 14.210 0 274  GLU A CG   1 ? 
ATOM   4180 C CD   A GLU A 1 259 ? -23.347 -0.321  -21.986 0.500 9.605  0 274  GLU A CD   1 ? 
ATOM   4181 C CD   B GLU A 1 259 ? -24.424 -0.689  -19.655 0.500 15.301 0 274  GLU A CD   1 ? 
ATOM   4182 O OE1  A GLU A 1 259 ? -24.239 -0.590  -21.188 0.500 10.167 0 274  GLU A OE1  1 ? 
ATOM   4183 O OE1  B GLU A 1 259 ? -24.732 -1.179  -20.770 0.500 17.864 0 274  GLU A OE1  1 ? 
ATOM   4184 O OE2  A GLU A 1 259 ? -23.481 -0.561  -23.222 0.500 9.530  0 274  GLU A OE2  1 ? 
ATOM   4185 O OE2  B GLU A 1 259 ? -24.818 -1.160  -18.558 0.500 15.035 0 274  GLU A OE2  1 ? 
ATOM   4186 H H    A GLU A 1 259 ? -21.477 0.137   -17.550 0.500 9.000  0 274  GLU A H    1 c 
ATOM   4187 H H    B GLU A 1 259 ? -21.481 0.112   -17.667 0.500 9.830  0 274  GLU A H    1 c 
ATOM   4188 H HA   A GLU A 1 259 ? -22.375 -1.458  -19.413 0.500 8.707  0 274  GLU A HA   1 c 
ATOM   4189 H HA   B GLU A 1 259 ? -22.283 -1.838  -19.330 0.500 10.290 0 274  GLU A HA   1 c 
ATOM   4190 H HB2  A GLU A 1 259 ? -22.578 0.881   -19.576 0.500 8.698  0 274  GLU A HB2  1 c 
ATOM   4191 H HB2  B GLU A 1 259 ? -21.504 0.838   -19.959 0.500 12.218 0 274  GLU A HB2  1 c 
ATOM   4192 H HB3  A GLU A 1 259 ? -21.027 1.022   -19.855 0.500 8.698  0 274  GLU A HB3  1 c 
ATOM   4193 H HB3  B GLU A 1 259 ? -22.119 -0.128  -21.051 0.500 12.218 0 274  GLU A HB3  1 c 
ATOM   4194 H HG2  A GLU A 1 259 ? -22.033 1.230   -21.891 0.500 8.749  0 274  GLU A HG2  1 c 
ATOM   4195 H HG2  B GLU A 1 259 ? -23.495 0.930   -18.800 0.500 13.985 0 274  GLU A HG2  1 c 
ATOM   4196 H HG3  A GLU A 1 259 ? -21.320 -0.165  -21.903 0.500 8.665  0 274  GLU A HG3  1 c 
ATOM   4197 H HG3  B GLU A 1 259 ? -23.867 1.169   -20.334 0.500 13.995 0 274  GLU A HG3  1 c 
ATOM   4198 N N    . ARG A 1 260 ? -19.169 -1.190  -19.643 1.000 8.117  0 275  ARG A N    1 ? 
ATOM   4199 C CA   . ARG A 1 260 ? -17.932 -1.617  -20.287 1.000 8.529  0 275  ARG A CA   1 ? 
ATOM   4200 C C    . ARG A 1 260 ? -17.094 -2.486  -19.320 1.000 7.845  0 275  ARG A C    1 ? 
ATOM   4201 O O    . ARG A 1 260 ? -15.874 -2.570  -19.460 1.000 7.771  0 275  ARG A O    1 ? 
ATOM   4202 C CB   . ARG A 1 260 ? -17.145 -0.395  -20.777 1.000 9.765  0 275  ARG A CB   1 ? 
ATOM   4203 C CG   . ARG A 1 260 ? -17.981 0.547   -21.648 1.000 11.521 0 275  ARG A CG   1 ? 
ATOM   4204 C CD   . ARG A 1 260 ? -17.089 1.637   -22.221 1.000 15.477 0 275  ARG A CD   1 ? 
ATOM   4205 N NE   . ARG A 1 260 ? -17.857 2.594   -23.027 1.000 20.377 0 275  ARG A NE   1 ? 
ATOM   4206 C CZ   . ARG A 1 260 ? -17.563 3.084   -24.248 1.000 29.777 0 275  ARG A CZ   1 ? 
ATOM   4207 N NH1  . ARG A 1 260 ? -18.500 3.765   -24.929 1.000 29.133 0 275  ARG A NH1  1 ? 
ATOM   4208 N NH2  . ARG A 1 260 ? -16.374 2.844   -24.806 1.000 32.578 0 275  ARG A NH2  1 ? 
ATOM   4209 H H    . ARG A 1 260 ? -19.106 -0.594  -18.953 1.000 8.486  0 275  ARG A H    1 c 
ATOM   4210 H HA   . ARG A 1 260 ? -18.160 -2.168  -21.077 1.000 8.534  0 275  ARG A HA   1 c 
ATOM   4211 H HB2  . ARG A 1 260 ? -16.810 0.102   -20.001 1.000 9.846  0 275  ARG A HB2  1 c 
ATOM   4212 H HB3  . ARG A 1 260 ? -16.370 -0.702  -21.295 1.000 9.824  0 275  ARG A HB3  1 c 
ATOM   4213 H HG2  . ARG A 1 260 ? -18.392 0.042   -22.383 1.000 11.873 0 275  ARG A HG2  1 c 
ATOM   4214 H HG3  . ARG A 1 260 ? -18.690 0.957   -21.107 1.000 11.854 0 275  ARG A HG3  1 c 
ATOM   4215 H HD2  . ARG A 1 260 ? -16.648 2.113   -21.487 1.000 15.473 0 275  ARG A HD2  1 c 
ATOM   4216 H HD3  . ARG A 1 260 ? -16.395 1.227   -22.776 1.000 15.571 0 275  ARG A HD3  1 c 
ATOM   4217 H HE   . ARG A 1 260 ? -18.597 2.887   -22.672 1.000 21.019 0 275  ARG A HE   1 c 
ATOM   4218 H HH11 . ARG A 1 260 ? -18.285 4.168   -25.686 1.000 29.313 0 275  ARG A HH11 1 c 
ATOM   4219 H HH12 . ARG A 1 260 ? -19.328 3.807   -24.621 1.000 29.169 0 275  ARG A HH12 1 c 
ATOM   4220 H HH21 . ARG A 1 260 ? -16.330 2.594   -25.653 1.000 31.657 0 275  ARG A HH21 1 c 
ATOM   4221 H HH22 . ARG A 1 260 ? -15.637 2.938   -24.327 1.000 31.551 0 275  ARG A HH22 1 c 
ATOM   4222 N N    . TYR A 1 261 ? -17.767 -3.158  -18.369 1.000 8.101  0 276  TYR A N    1 ? 
ATOM   4223 C CA   . TYR A 1 261 ? -17.046 -3.945  -17.373 1.000 7.406  0 276  TYR A CA   1 ? 
ATOM   4224 C C    . TYR A 1 261 ? -17.689 -5.335  -17.254 1.000 7.259  0 276  TYR A C    1 ? 
ATOM   4225 O O    . TYR A 1 261 ? -18.423 -5.638  -16.322 1.000 7.593  0 276  TYR A O    1 ? 
ATOM   4226 C CB   . TYR A 1 261 ? -16.992 -3.212  -16.051 1.000 7.830  0 276  TYR A CB   1 ? 
ATOM   4227 C CG   . TYR A 1 261 ? -15.969 -3.684  -15.039 1.000 7.162  0 276  TYR A CG   1 ? 
ATOM   4228 C CD1  . TYR A 1 261 ? -15.317 -4.915  -15.111 1.000 7.617  0 276  TYR A CD1  1 ? 
ATOM   4229 C CD2  . TYR A 1 261 ? -15.641 -2.866  -13.968 1.000 8.286  0 276  TYR A CD2  1 ? 
ATOM   4230 C CE1  . TYR A 1 261 ? -14.382 -5.297  -14.177 1.000 7.264  0 276  TYR A CE1  1 ? 
ATOM   4231 C CE2  . TYR A 1 261 ? -14.668 -3.219  -13.054 1.000 8.024  0 276  TYR A CE2  1 ? 
ATOM   4232 C CZ   . TYR A 1 261 ? -14.078 -4.458  -13.119 1.000 7.700  0 276  TYR A CZ   1 ? 
ATOM   4233 O OH   . TYR A 1 261 ? -13.162 -4.795  -12.136 1.000 7.980  0 276  TYR A OH   1 ? 
ATOM   4234 H H    . TYR A 1 261 ? -18.680 -3.136  -18.343 1.000 7.890  0 276  TYR A H    1 c 
ATOM   4235 H HA   . TYR A 1 261 ? -16.113 -4.066  -17.690 1.000 7.590  0 276  TYR A HA   1 c 
ATOM   4236 H HB2  . TYR A 1 261 ? -16.821 -2.262  -16.240 1.000 7.577  0 276  TYR A HB2  1 c 
ATOM   4237 H HB3  . TYR A 1 261 ? -17.882 -3.261  -15.638 1.000 7.573  0 276  TYR A HB3  1 c 
ATOM   4238 H HD1  . TYR A 1 261 ? -15.521 -5.506  -15.818 1.000 7.437  0 276  TYR A HD1  1 c 
ATOM   4239 H HD2  . TYR A 1 261 ? -16.042 -2.013  -13.902 1.000 7.943  0 276  TYR A HD2  1 c 
ATOM   4240 H HE1  . TYR A 1 261 ? -13.970 -6.142  -14.240 1.000 7.455  0 276  TYR A HE1  1 c 
ATOM   4241 H HE2  . TYR A 1 261 ? -14.485 -2.654  -12.323 1.000 7.995  0 276  TYR A HE2  1 c 
ATOM   4242 H HH   . TYR A 1 261 ? -12.377 -4.531  -12.364 0.000 7.980  0 276  TYR A HH   1 c 
ATOM   4243 N N    . PRO A 1 262 ? -17.411 -6.228  -18.238 1.000 7.759  0 277  PRO A N    1 ? 
ATOM   4244 C CA   . PRO A 1 262 ? -18.039 -7.558  -18.241 1.000 7.421  0 277  PRO A CA   1 ? 
ATOM   4245 C C    . PRO A 1 262 ? -17.960 -8.305  -16.911 1.000 7.230  0 277  PRO A C    1 ? 
ATOM   4246 O O    . PRO A 1 262 ? -18.936 -8.878  -16.442 1.000 8.227  0 277  PRO A O    1 ? 
ATOM   4247 C CB   . PRO A 1 262 ? -17.285 -8.286  -19.408 1.000 7.754  0 277  PRO A CB   1 ? 
ATOM   4248 C CG   . PRO A 1 262 ? -16.889 -7.158  -20.328 1.000 8.412  0 277  PRO A CG   1 ? 
ATOM   4249 C CD   . PRO A 1 262 ? -16.600 -5.960  -19.444 1.000 7.665  0 277  PRO A CD   1 ? 
ATOM   4250 H HA   . PRO A 1 262 ? -18.990 -7.447  -18.494 1.000 7.509  0 277  PRO A HA   1 c 
ATOM   4251 H HB2  . PRO A 1 262 ? -16.490 -8.763  -19.071 1.000 7.826  0 277  PRO A HB2  1 c 
ATOM   4252 H HB3  . PRO A 1 262 ? -17.875 -8.927  -19.866 1.000 7.830  0 277  PRO A HB3  1 c 
ATOM   4253 H HG2  . PRO A 1 262 ? -16.093 -7.401  -20.846 1.000 8.088  0 277  PRO A HG2  1 c 
ATOM   4254 H HG3  . PRO A 1 262 ? -17.616 -6.954  -20.953 1.000 8.096  0 277  PRO A HG3  1 c 
ATOM   4255 H HD2  . PRO A 1 262 ? -15.644 -5.905  -19.224 1.000 7.854  0 277  PRO A HD2  1 c 
ATOM   4256 H HD3  . PRO A 1 262 ? -16.879 -5.128  -19.883 1.000 7.849  0 277  PRO A HD3  1 c 
ATOM   4257 N N    . MET A 1 263 ? -16.752 -8.363  -16.310 1.000 7.207  0 278  MET A N    1 ? 
ATOM   4258 C CA   . MET A 1 263 ? -16.603 -9.185  -15.111 1.000 7.244  0 278  MET A CA   1 ? 
ATOM   4259 C C    . MET A 1 263 ? -17.454 -8.668  -13.957 1.000 7.353  0 278  MET A C    1 ? 
ATOM   4260 O O    . MET A 1 263 ? -17.904 -9.438  -13.099 1.000 7.856  0 278  MET A O    1 ? 
ATOM   4261 C CB   . MET A 1 263 ? -15.139 -9.368  -14.706 1.000 8.202  0 278  MET A CB   1 ? 
ATOM   4262 C CG   . MET A 1 263 ? -14.355 -10.240 -15.696 1.000 8.361  0 278  MET A CG   1 ? 
ATOM   4263 S SD   . MET A 1 263 ? -12.630 -10.481 -15.204 1.000 11.110 0 278  MET A SD   1 ? 
ATOM   4264 C CE   . MET A 1 263 ? -11.958 -8.907  -15.661 1.000 12.874 0 278  MET A CE   1 ? 
ATOM   4265 H H    . MET A 1 263 ? -16.035 -7.902  -16.640 1.000 7.231  0 278  MET A H    1 c 
ATOM   4266 H HA   . MET A 1 263 ? -16.962 -10.081 -15.339 1.000 7.428  0 278  MET A HA   1 c 
ATOM   4267 H HB2  . MET A 1 263 ? -14.714 -8.486  -14.646 1.000 8.031  0 278  MET A HB2  1 c 
ATOM   4268 H HB3  . MET A 1 263 ? -15.105 -9.781  -13.817 1.000 8.009  0 278  MET A HB3  1 c 
ATOM   4269 H HG2  . MET A 1 263 ? -14.786 -11.115 -15.769 1.000 8.788  0 278  MET A HG2  1 c 
ATOM   4270 H HG3  . MET A 1 263 ? -14.374 -9.823  -16.577 1.000 8.788  0 278  MET A HG3  1 c 
ATOM   4271 H HE1  . MET A 1 263 ? -11.003 -8.891  -15.464 1.000 12.391 0 278  MET A HE1  1 c 
ATOM   4272 H HE2  . MET A 1 263 ? -12.095 -8.760  -16.615 1.000 12.391 0 278  MET A HE2  1 c 
ATOM   4273 H HE3  . MET A 1 263 ? -12.406 -8.203  -15.156 1.000 12.362 0 278  MET A HE3  1 c 
ATOM   4274 N N    . ALA A 1 264 ? -17.603 -7.329  -13.858 1.000 7.627  0 279  ALA A N    1 ? 
ATOM   4275 C CA   . ALA A 1 264 ? -18.435 -6.744  -12.809 1.000 7.712  0 279  ALA A CA   1 ? 
ATOM   4276 C C    . ALA A 1 264 ? -19.873 -7.212  -12.931 1.000 7.797  0 279  ALA A C    1 ? 
ATOM   4277 O O    . ALA A 1 264 ? -20.552 -7.449  -11.915 1.000 8.217  0 279  ALA A O    1 ? 
ATOM   4278 C CB   . ALA A 1 264 ? -18.379 -5.225  -12.846 1.000 7.885  0 279  ALA A CB   1 ? 
ATOM   4279 H H    . ALA A 1 264 ? -17.180 -6.777  -14.451 1.000 7.577  0 279  ALA A H    1 c 
ATOM   4280 H HA   . ALA A 1 264 ? -18.084 -7.056  -11.930 1.000 7.743  0 279  ALA A HA   1 c 
ATOM   4281 H HB1  . ALA A 1 264 ? -17.463 -4.929  -12.715 1.000 7.834  0 279  ALA A HB1  1 c 
ATOM   4282 H HB2  . ALA A 1 264 ? -18.699 -4.907  -13.707 1.000 7.834  0 279  ALA A HB2  1 c 
ATOM   4283 H HB3  . ALA A 1 264 ? -18.939 -4.860  -12.141 1.000 7.834  0 279  ALA A HB3  1 c 
ATOM   4284 N N    . LEU A 1 265 ? -20.369 -7.347  -14.157 1.000 8.397  0 280  LEU A N    1 ? 
ATOM   4285 C CA   . LEU A 1 265 ? -21.716 -7.869  -14.393 1.000 8.524  0 280  LEU A CA   1 ? 
ATOM   4286 C C    . LEU A 1 265 ? -21.856 -9.335  -13.964 1.000 8.883  0 280  LEU A C    1 ? 
ATOM   4287 O O    . LEU A 1 265 ? -22.847 -9.737  -13.369 1.000 8.690  0 280  LEU A O    1 ? 
ATOM   4288 C CB   . LEU A 1 265 ? -22.137 -7.651  -15.839 1.000 9.576  0 280  LEU A CB   1 ? 
ATOM   4289 C CG   . LEU A 1 265 ? -22.326 -6.182  -16.223 1.000 9.999  0 280  LEU A CG   1 ? 
ATOM   4290 C CD1  . LEU A 1 265 ? -22.204 -5.965  -17.711 1.000 9.685  0 280  LEU A CD1  1 ? 
ATOM   4291 C CD2  . LEU A 1 265 ? -23.649 -5.636  -15.721 1.000 10.950 0 280  LEU A CD2  1 ? 
ATOM   4292 H H    . LEU A 1 265 ? -19.862 -7.101  -14.877 1.000 8.277  0 280  LEU A H    1 c 
ATOM   4293 H HA   . LEU A 1 265 ? -22.330 -7.347  -13.817 1.000 8.761  0 280  LEU A HA   1 c 
ATOM   4294 H HB2  . LEU A 1 265 ? -21.451 -8.044  -16.426 1.000 9.412  0 280  LEU A HB2  1 c 
ATOM   4295 H HB3  . LEU A 1 265 ? -22.987 -8.127  -15.991 1.000 9.420  0 280  LEU A HB3  1 c 
ATOM   4296 H HG   . LEU A 1 265 ? -21.605 -5.659  -15.787 1.000 10.020 0 280  LEU A HG   1 c 
ATOM   4297 H HD11 . LEU A 1 265 ? -21.323 -6.245  -18.009 1.000 9.778  0 280  LEU A HD11 1 c 
ATOM   4298 H HD12 . LEU A 1 265 ? -22.329 -5.022  -17.913 1.000 9.783  0 280  LEU A HD12 1 c 
ATOM   4299 H HD13 . LEU A 1 265 ? -22.882 -6.487  -18.172 1.000 9.778  0 280  LEU A HD13 1 c 
ATOM   4300 H HD21 . LEU A 1 265 ? -23.670 -5.676  -14.750 1.000 10.643 0 280  LEU A HD21 1 c 
ATOM   4301 H HD22 . LEU A 1 265 ? -24.378 -6.167  -16.082 1.000 10.654 0 280  LEU A HD22 1 c 
ATOM   4302 H HD23 . LEU A 1 265 ? -23.749 -4.713  -16.008 1.000 10.650 0 280  LEU A HD23 1 c 
ATOM   4303 N N    . GLY A 1 266 ? -20.797 -10.123 -14.181 1.000 8.629  0 281  GLY A N    1 ? 
ATOM   4304 C CA   . GLY A 1 266 ? -20.751 -11.493 -13.682 1.000 8.383  0 281  GLY A CA   1 ? 
ATOM   4305 C C    . GLY A 1 266 ? -20.727 -11.561 -12.165 1.000 8.423  0 281  GLY A C    1 ? 
ATOM   4306 O O    . GLY A 1 266 ? -21.414 -12.368 -11.547 1.000 8.977  0 281  GLY A O    1 ? 
ATOM   4307 H H    . GLY A 1 266 ? -20.087 -9.804  -14.659 1.000 8.630  0 281  GLY A H    1 c 
ATOM   4308 H HA2  . GLY A 1 266 ? -21.539 -11.982 -14.018 1.000 8.451  0 281  GLY A HA2  1 c 
ATOM   4309 H HA3  . GLY A 1 266 ? -19.947 -11.937 -14.041 1.000 8.450  0 281  GLY A HA3  1 c 
ATOM   4310 N N    . ASN A 1 267 ? -19.939 -10.686 -11.540 1.000 8.631  0 282  ASN A N    1 ? 
ATOM   4311 C CA   . ASN A 1 267 ? -19.922 -10.621 -10.082 1.000 8.625  0 282  ASN A CA   1 ? 
ATOM   4312 C C    . ASN A 1 267 ? -21.308 -10.297 -9.540  1.000 8.835  0 282  ASN A C    1 ? 
ATOM   4313 O O    . ASN A 1 267 ? -21.767 -10.900 -8.557  1.000 9.091  0 282  ASN A O    1 ? 
ATOM   4314 C CB   . ASN A 1 267 ? -18.891 -9.582  -9.663  1.000 9.364  0 282  ASN A CB   1 ? 
ATOM   4315 C CG   . ASN A 1 267 ? -18.566 -9.444  -8.192  1.000 10.835 0 282  ASN A CG   1 ? 
ATOM   4316 O OD1  . ASN A 1 267 ? -19.180 -10.029 -7.243  1.000 14.273 0 282  ASN A OD1  1 ? 
ATOM   4317 N ND2  . ASN A 1 267 ? -17.648 -8.570  -7.917  1.000 10.003 0 282  ASN A ND2  1 ? 
ATOM   4318 H H    . ASN A 1 267 ? -19.402 -10.125 -12.020 1.000 8.591  0 282  ASN A H    1 c 
ATOM   4319 H HA   . ASN A 1 267 ? -19.634 -11.494 -9.731  1.000 8.798  0 282  ASN A HA   1 c 
ATOM   4320 H HB2  . ASN A 1 267 ? -18.058 -9.781  -10.134 1.000 9.474  0 282  ASN A HB2  1 c 
ATOM   4321 H HB3  . ASN A 1 267 ? -19.197 -8.710  -9.984  1.000 9.492  0 282  ASN A HB3  1 c 
ATOM   4322 H HD21 . ASN A 1 267 ? -17.499 -7.892  -8.470  1.000 10.252 0 282  ASN A HD21 1 c 
ATOM   4323 H HD22 . ASN A 1 267 ? -17.170 -8.650  -7.174  1.000 10.277 0 282  ASN A HD22 1 c 
ATOM   4324 N N    . LEU A 1 268 ? -21.979 -9.307  -10.150 1.000 8.215  0 283  LEU A N    1 ? 
ATOM   4325 C CA   . LEU A 1 268 ? -23.303 -8.920  -9.690  1.000 9.026  0 283  LEU A CA   1 ? 
ATOM   4326 C C    . LEU A 1 268 ? -24.266 -10.086 -9.868  1.000 9.106  0 283  LEU A C    1 ? 
ATOM   4327 O O    . LEU A 1 268 ? -25.105 -10.345 -8.986  1.000 9.234  0 283  LEU A O    1 ? 
ATOM   4328 C CB   . LEU A 1 268 ? -23.722 -7.654  -10.435 1.000 9.708  0 283  LEU A CB   1 ? 
ATOM   4329 C CG   . LEU A 1 268 ? -25.096 -7.059  -10.081 1.000 9.445  0 283  LEU A CG   1 ? 
ATOM   4330 C CD1  . LEU A 1 268 ? -25.189 -6.814  -8.593  1.000 9.819  0 283  LEU A CD1  1 ? 
ATOM   4331 C CD2  . LEU A 1 268 ? -25.311 -5.785  -10.814 1.000 9.837  0 283  LEU A CD2  1 ? 
ATOM   4332 H H    . LEU A 1 268 ? -21.604 -8.866  -10.858 1.000 8.546  0 283  LEU A H    1 c 
ATOM   4333 H HA   . LEU A 1 268 ? -23.241 -8.716  -8.722  1.000 9.002  0 283  LEU A HA   1 c 
ATOM   4334 H HB2  . LEU A 1 268 ? -23.037 -6.965  -10.274 1.000 9.488  0 283  LEU A HB2  1 c 
ATOM   4335 H HB3  . LEU A 1 268 ? -23.712 -7.851  -11.400 1.000 9.488  0 283  LEU A HB3  1 c 
ATOM   4336 H HG   . LEU A 1 268 ? -25.801 -7.704  -10.345 1.000 9.632  0 283  LEU A HG   1 c 
ATOM   4337 H HD11 . LEU A 1 268 ? -25.266 -7.664  -8.127  1.000 9.698  0 283  LEU A HD11 1 c 
ATOM   4338 H HD12 . LEU A 1 268 ? -25.971 -6.270  -8.400  1.000 9.707  0 283  LEU A HD12 1 c 
ATOM   4339 H HD13 . LEU A 1 268 ? -24.391 -6.350  -8.289  1.000 9.705  0 283  LEU A HD13 1 c 
ATOM   4340 H HD21 . LEU A 1 268 ? -25.255 -5.947  -11.770 1.000 9.716  0 283  LEU A HD21 1 c 
ATOM   4341 H HD22 . LEU A 1 268 ? -24.630 -5.142  -10.554 1.000 9.716  0 283  LEU A HD22 1 c 
ATOM   4342 H HD23 . LEU A 1 268 ? -26.190 -5.430  -10.598 1.000 9.714  0 283  LEU A HD23 1 c 
ATOM   4343 N N    . ALA A 1 269 ? -24.181 -10.795 -10.978 1.000 9.150  0 284  ALA A N    1 ? 
ATOM   4344 C CA   . ALA A 1 269 ? -25.025 -11.967 -11.214 1.000 9.407  0 284  ALA A CA   1 ? 
ATOM   4345 C C    . ALA A 1 269 ? -24.819 -13.031 -10.118 1.000 9.813  0 284  ALA A C    1 ? 
ATOM   4346 O O    . ALA A 1 269 ? -25.776 -13.614 -9.548  1.000 9.802  0 284  ALA A O    1 ? 
ATOM   4347 C CB   . ALA A 1 269 ? -24.759 -12.535 -12.575 1.000 9.509  0 284  ALA A CB   1 ? 
ATOM   4348 H H    . ALA A 1 269 ? -23.585 -10.546 -11.624 1.000 9.190  0 284  ALA A H    1 c 
ATOM   4349 H HA   . ALA A 1 269 ? -25.976 -11.670 -11.174 1.000 9.446  0 284  ALA A HA   1 c 
ATOM   4350 H HB1  . ALA A 1 269 ? -24.869 -11.842 -13.246 1.000 9.495  0 284  ALA A HB1  1 c 
ATOM   4351 H HB2  . ALA A 1 269 ? -23.849 -12.874 -12.613 1.000 9.482  0 284  ALA A HB2  1 c 
ATOM   4352 H HB3  . ALA A 1 269 ? -25.380 -13.260 -12.755 1.000 9.484  0 284  ALA A HB3  1 c 
ATOM   4353 N N    . ASP A 1 270 ? -23.543 -13.282 -9.766  1.000 8.913  0 285  ASP A N    1 ? 
ATOM   4354 C CA   . ASP A 1 270 ? -23.227 -14.231 -8.721  1.000 9.376  0 285  ASP A CA   1 ? 
ATOM   4355 C C    . ASP A 1 270 ? -23.850 -13.795 -7.389  1.000 10.451 0 285  ASP A C    1 ? 
ATOM   4356 O O    . ASP A 1 270 ? -24.330 -14.643 -6.615  1.000 11.526 0 285  ASP A O    1 ? 
ATOM   4357 C CB   . ASP A 1 270 ? -21.712 -14.405 -8.590  1.000 10.761 0 285  ASP A CB   1 ? 
ATOM   4358 C CG   . ASP A 1 270 ? -20.965 -15.206 -9.639  1.000 12.124 0 285  ASP A CG   1 ? 
ATOM   4359 O OD1  . ASP A 1 270 ? -21.607 -15.812 -10.509 1.000 11.590 0 285  ASP A OD1  1 ? 
ATOM   4360 O OD2  . ASP A 1 270 ? -19.710 -15.241 -9.516  1.000 13.294 0 285  ASP A OD2  1 ? 
ATOM   4361 H H    . ASP A 1 270 ? -22.861 -12.851 -10.195 1.000 9.246  0 285  ASP A H    1 c 
ATOM   4362 H HA   . ASP A 1 270 ? -23.609 -15.102 -8.972  1.000 9.722  0 285  ASP A HA   1 c 
ATOM   4363 H HB2  . ASP A 1 270 ? -21.308 -13.513 -8.563  1.000 10.701 0 285  ASP A HB2  1 c 
ATOM   4364 H HB3  . ASP A 1 270 ? -21.534 -14.829 -7.725  1.000 10.716 0 285  ASP A HB3  1 c 
ATOM   4365 N N    . LEU A 1 271 ? -23.800 -12.503 -7.069  1.000 9.645  0 286  LEU A N    1 ? 
ATOM   4366 C CA   . LEU A 1 271 ? -24.370 -11.995 -5.819  1.000 10.126 0 286  LEU A CA   1 ? 
ATOM   4367 C C    . LEU A 1 271 ? -25.898 -12.154 -5.817  1.000 10.575 0 286  LEU A C    1 ? 
ATOM   4368 O O    . LEU A 1 271 ? -26.482 -12.528 -4.777  1.000 10.666 0 286  LEU A O    1 ? 
ATOM   4369 C CB   . LEU A 1 271 ? -23.964 -10.542 -5.589  1.000 10.585 0 286  LEU A CB   1 ? 
ATOM   4370 C CG   . LEU A 1 271 ? -22.488 -10.367 -5.213  1.000 10.125 0 286  LEU A CG   1 ? 
ATOM   4371 C CD1  . LEU A 1 271 ? -22.117 -8.891  -5.391  1.000 10.653 0 286  LEU A CD1  1 ? 
ATOM   4372 C CD2  . LEU A 1 271 ? -22.118 -10.801 -3.806  1.000 11.806 0 286  LEU A CD2  1 ? 
ATOM   4373 H H    . LEU A 1 271 ? -23.394 -11.915 -7.639  1.000 9.936  0 286  LEU A H    1 c 
ATOM   4374 H HA   . LEU A 1 271 ? -24.009 -12.544 -5.078  1.000 10.214 0 286  LEU A HA   1 c 
ATOM   4375 H HB2  . LEU A 1 271 ? -24.143 -10.034 -6.413  1.000 10.373 0 286  LEU A HB2  1 c 
ATOM   4376 H HB3  . LEU A 1 271 ? -24.520 -10.174 -4.863  1.000 10.375 0 286  LEU A HB3  1 c 
ATOM   4377 H HG   . LEU A 1 271 ? -21.944 -10.898 -5.849  1.000 10.593 0 286  LEU A HG   1 c 
ATOM   4378 H HD11 . LEU A 1 271 ? -22.259 -8.630  -6.316  1.000 10.499 0 286  LEU A HD11 1 c 
ATOM   4379 H HD12 . LEU A 1 271 ? -21.183 -8.761  -5.159  1.000 10.515 0 286  LEU A HD12 1 c 
ATOM   4380 H HD13 . LEU A 1 271 ? -22.673 -8.344  -4.811  1.000 10.500 0 286  LEU A HD13 1 c 
ATOM   4381 H HD21 . LEU A 1 271 ? -22.290 -11.752 -3.703  1.000 11.272 0 286  LEU A HD21 1 c 
ATOM   4382 H HD22 . LEU A 1 271 ? -22.650 -10.305 -3.162  1.000 11.278 0 286  LEU A HD22 1 c 
ATOM   4383 H HD23 . LEU A 1 271 ? -21.174 -10.625 -3.650  1.000 11.274 0 286  LEU A HD23 1 c 
ATOM   4384 N N    . GLU A 1 272 ? -26.532 -11.889 -6.950  1.000 10.448 0 287  GLU A N    1 ? 
ATOM   4385 C CA   . GLU A 1 272 ? -27.975 -12.065 -7.095  1.000 10.575 0 287  GLU A CA   1 ? 
ATOM   4386 C C    . GLU A 1 272 ? -28.366 -13.526 -6.950  1.000 12.153 0 287  GLU A C    1 ? 
ATOM   4387 O O    . GLU A 1 272 ? -29.411 -13.811 -6.339  1.000 12.851 0 287  GLU A O    1 ? 
ATOM   4388 C CB   . GLU A 1 272 ? -28.442 -11.486 -8.413  1.000 10.595 0 287  GLU A CB   1 ? 
ATOM   4389 C CG   . GLU A 1 272 ? -28.455 -9.967  -8.435  1.000 11.566 0 287  GLU A CG   1 ? 
ATOM   4390 C CD   . GLU A 1 272 ? -29.459 -9.351  -7.457  1.000 12.832 0 287  GLU A CD   1 ? 
ATOM   4391 O OE1  . GLU A 1 272 ? -30.640 -9.737  -7.533  1.000 12.162 0 287  GLU A OE1  1 ? 
ATOM   4392 O OE2  . GLU A 1 272 ? -29.035 -8.495  -6.628  1.000 12.474 0 287  GLU A OE2  1 ? 
ATOM   4393 H H    . GLU A 1 272 ? -26.055 -11.578 -7.664  1.000 10.501 0 287  GLU A H    1 c 
ATOM   4394 H HA   . GLU A 1 272 ? -28.415 -11.560 -6.366  1.000 10.846 0 287  GLU A HA   1 c 
ATOM   4395 H HB2  . GLU A 1 272 ? -27.854 -11.810 -9.127  1.000 10.805 0 287  GLU A HB2  1 c 
ATOM   4396 H HB3  . GLU A 1 272 ? -29.346 -11.814 -8.600  1.000 10.818 0 287  GLU A HB3  1 c 
ATOM   4397 H HG2  . GLU A 1 272 ? -27.559 -9.635  -8.214  1.000 11.599 0 287  GLU A HG2  1 c 
ATOM   4398 H HG3  . GLU A 1 272 ? -28.672 -9.661  -9.341  1.000 11.606 0 287  GLU A HG3  1 c 
ATOM   4399 N N    . GLU A 1 273 ? -27.560 -14.456 -7.457  1.000 11.319 0 288  GLU A N    1 ? 
ATOM   4400 C CA   . GLU A 1 273 ? -27.870 -15.867 -7.248  1.000 12.225 0 288  GLU A CA   1 ? 
ATOM   4401 C C    . GLU A 1 273 ? -27.890 -16.194 -5.765  1.000 13.690 0 288  GLU A C    1 ? 
ATOM   4402 O O    . GLU A 1 273 ? -28.755 -16.933 -5.285  1.000 14.709 0 288  GLU A O    1 ? 
ATOM   4403 C CB   . GLU A 1 273 ? -26.850 -16.733 -7.991  1.000 13.990 0 288  GLU A CB   1 ? 
ATOM   4404 C CG   . GLU A 1 273 ? -27.123 -18.233 -7.900  1.000 17.648 0 288  GLU A CG   1 ? 
ATOM   4405 C CD   . GLU A 1 273 ? -25.984 -19.105 -8.392  1.000 19.405 0 288  GLU A CD   1 ? 
ATOM   4406 O OE1  . GLU A 1 273 ? -24.882 -18.608 -8.622  1.000 21.970 0 288  GLU A OE1  1 ? 
ATOM   4407 O OE2  . GLU A 1 273 ? -26.315 -20.318 -8.470  1.000 26.706 0 288  GLU A OE2  1 ? 
ATOM   4408 H H    . GLU A 1 273 ? -26.819 -14.221 -7.938  1.000 11.710 0 288  GLU A H    1 c 
ATOM   4409 H HA   . GLU A 1 273 ? -28.770 -16.046 -7.623  1.000 12.601 0 288  GLU A HA   1 c 
ATOM   4410 H HB2  . GLU A 1 273 ? -26.843 -16.471 -8.935  1.000 14.316 0 288  GLU A HB2  1 c 
ATOM   4411 H HB3  . GLU A 1 273 ? -25.960 -16.549 -7.625  1.000 14.349 0 288  GLU A HB3  1 c 
ATOM   4412 H HG2  . GLU A 1 273 ? -27.312 -18.470 -6.968  1.000 17.087 0 288  GLU A HG2  1 c 
ATOM   4413 H HG3  . GLU A 1 273 ? -27.924 -18.444 -8.426  1.000 17.151 0 288  GLU A HG3  1 c 
ATOM   4414 N N    . LEU A 1 274 ? -26.910 -15.685 -5.026  1.000 12.227 0 289  LEU A N    1 ? 
ATOM   4415 C CA   . LEU A 1 274 ? -26.774 -15.934 -3.606  1.000 14.834 0 289  LEU A CA   1 ? 
ATOM   4416 C C    . LEU A 1 274 ? -27.953 -15.333 -2.832  1.000 13.773 0 289  LEU A C    1 ? 
ATOM   4417 O O    . LEU A 1 274 ? -28.520 -15.945 -1.907  1.000 16.703 0 289  LEU A O    1 ? 
ATOM   4418 C CB   . LEU A 1 274 ? -25.434 -15.333 -3.169  1.000 18.085 0 289  LEU A CB   1 ? 
ATOM   4419 C CG   . LEU A 1 274 ? -25.066 -15.472 -1.698  1.000 22.242 0 289  LEU A CG   1 ? 
ATOM   4420 C CD1  . LEU A 1 274 ? -24.914 -16.928 -1.325  1.000 21.988 0 289  LEU A CD1  1 ? 
ATOM   4421 C CD2  . LEU A 1 274 ? -23.790 -14.694 -1.448  1.000 24.556 0 289  LEU A CD2  1 ? 
ATOM   4422 H H    . LEU A 1 274 ? -26.286 -15.155 -5.434  1.000 13.169 0 289  LEU A H    1 c 
ATOM   4423 H HA   . LEU A 1 274 ? -26.759 -16.914 -3.460  1.000 14.674 0 289  LEU A HA   1 c 
ATOM   4424 H HB2  . LEU A 1 274 ? -24.723 -15.752 -3.706  1.000 18.119 0 289  LEU A HB2  1 c 
ATOM   4425 H HB3  . LEU A 1 274 ? -25.441 -14.375 -3.394  1.000 18.093 0 289  LEU A HB3  1 c 
ATOM   4426 H HG   . LEU A 1 274 ? -25.790 -15.076 -1.149  1.000 21.709 0 289  LEU A HG   1 c 
ATOM   4427 H HD11 . LEU A 1 274 ? -25.778 -17.370 -1.379  1.000 21.955 0 289  LEU A HD11 1 c 
ATOM   4428 H HD12 . LEU A 1 274 ? -24.573 -16.997 -0.418  1.000 22.038 0 289  LEU A HD12 1 c 
ATOM   4429 H HD13 . LEU A 1 274 ? -24.292 -17.357 -1.937  1.000 22.038 0 289  LEU A HD13 1 c 
ATOM   4430 H HD21 . LEU A 1 274 ? -23.944 -13.751 -1.628  1.000 23.726 0 289  LEU A HD21 1 c 
ATOM   4431 H HD22 . LEU A 1 274 ? -23.088 -15.025 -2.033  1.000 23.798 0 289  LEU A HD22 1 c 
ATOM   4432 H HD23 . LEU A 1 274 ? -23.517 -14.805 -0.522  1.000 23.717 0 289  LEU A HD23 1 c 
ATOM   4433 N N    . GLU A 1 275 ? -28.342 -14.087 -3.160  1.000 12.956 0 290  GLU A N    1 ? 
ATOM   4434 C CA   . GLU A 1 275 ? -29.385 -13.407 -2.415  1.000 13.794 0 290  GLU A CA   1 ? 
ATOM   4435 C C    . GLU A 1 275 ? -30.068 -12.425 -3.339  1.000 12.319 0 290  GLU A C    1 ? 
ATOM   4436 O O    . GLU A 1 275 ? -29.607 -11.296 -3.512  1.000 12.867 0 290  GLU A O    1 ? 
ATOM   4437 C CB   . GLU A 1 275 ? -28.827 -12.674 -1.210  1.000 16.274 0 290  GLU A CB   1 ? 
ATOM   4438 C CG   . GLU A 1 275 ? -29.916 -12.108 -0.301  1.000 20.071 0 290  GLU A CG   1 ? 
ATOM   4439 C CD   . GLU A 1 275 ? -30.562 -13.231 0.456   1.000 27.055 0 290  GLU A CD   1 ? 
ATOM   4440 O OE1  . GLU A 1 275 ? -31.699 -13.579 0.089   1.000 35.232 0 290  GLU A OE1  1 ? 
ATOM   4441 O OE2  . GLU A 1 275 ? -29.885 -13.801 1.336   1.000 36.381 0 290  GLU A OE2  1 ? 
ATOM   4442 H H    . GLU A 1 275 ? -27.941 -13.655 -3.859  1.000 13.328 0 290  GLU A H    1 c 
ATOM   4443 H HA   . GLU A 1 275 ? -30.045 -14.077 -2.109  1.000 13.842 0 290  GLU A HA   1 c 
ATOM   4444 H HB2  . GLU A 1 275 ? -28.268 -13.293 -0.696  1.000 16.545 0 290  GLU A HB2  1 c 
ATOM   4445 H HB3  . GLU A 1 275 ? -28.253 -11.942 -1.519  1.000 16.407 0 290  GLU A HB3  1 c 
ATOM   4446 H HG2  . GLU A 1 275 ? -29.522 -11.473 0.334   1.000 20.527 0 290  GLU A HG2  1 c 
ATOM   4447 H HG3  . GLU A 1 275 ? -30.594 -11.643 -0.836  1.000 20.542 0 290  GLU A HG3  1 c 
ATOM   4448 N N    . PRO A 1 276 ? -31.159 -12.813 -4.018  1.000 13.371 0 291  PRO A N    1 ? 
ATOM   4449 C CA   . PRO A 1 276 ? -31.772 -11.970 -5.031  1.000 13.753 0 291  PRO A CA   1 ? 
ATOM   4450 C C    . PRO A 1 276 ? -32.338 -10.682 -4.464  1.000 14.690 0 291  PRO A C    1 ? 
ATOM   4451 O O    . PRO A 1 276 ? -32.934 -10.695 -3.381  1.000 16.105 0 291  PRO A O    1 ? 
ATOM   4452 C CB   . PRO A 1 276 ? -32.843 -12.816 -5.708  1.000 16.760 0 291  PRO A CB   1 ? 
ATOM   4453 C CG   . PRO A 1 276 ? -32.946 -14.013 -4.851  1.000 18.708 0 291  PRO A CG   1 ? 
ATOM   4454 C CD   . PRO A 1 276 ? -31.720 -14.169 -3.991  1.000 15.864 0 291  PRO A CD   1 ? 
ATOM   4455 H HA   . PRO A 1 276 ? -31.075 -11.751 -5.698  1.000 14.334 0 291  PRO A HA   1 c 
ATOM   4456 H HB2  . PRO A 1 276 ? -33.703 -12.334 -5.746  1.000 16.447 0 291  PRO A HB2  1 c 
ATOM   4457 H HB3  . PRO A 1 276 ? -32.572 -13.060 -6.623  1.000 16.484 0 291  PRO A HB3  1 c 
ATOM   4458 H HG2  . PRO A 1 276 ? -33.739 -13.941 -4.279  1.000 17.562 0 291  PRO A HG2  1 c 
ATOM   4459 H HG3  . PRO A 1 276 ? -33.056 -14.810 -5.411  1.000 17.562 0 291  PRO A HG3  1 c 
ATOM   4460 H HD2  . PRO A 1 276 ? -31.961 -14.440 -3.078  1.000 15.798 0 291  PRO A HD2  1 c 
ATOM   4461 H HD3  . PRO A 1 276 ? -31.095 -14.823 -4.376  1.000 15.818 0 291  PRO A HD3  1 c 
ATOM   4462 N N    . THR A 1 277 ? -32.168 -9.603  -5.198  1.000 13.057 0 292  THR A N    1 ? 
ATOM   4463 C CA   . THR A 1 277 ? -32.751 -8.305  -4.882  1.000 13.649 0 292  THR A CA   1 ? 
ATOM   4464 C C    . THR A 1 277 ? -34.118 -8.210  -5.561  1.000 14.865 0 292  THR A C    1 ? 
ATOM   4465 O O    . THR A 1 277 ? -34.189 -8.249  -6.782  1.000 14.710 0 292  THR A O    1 ? 
ATOM   4466 C CB   . THR A 1 277 ? -31.845 -7.178  -5.347  1.000 13.077 0 292  THR A CB   1 ? 
ATOM   4467 O OG1  . THR A 1 277 ? -30.548 -7.332  -4.808  1.000 13.097 0 292  THR A OG1  1 ? 
ATOM   4468 C CG2  . THR A 1 277 ? -32.379 -5.834  -4.912  1.000 15.037 0 292  THR A CG2  1 ? 
ATOM   4469 H H    . THR A 1 277 ? -31.662 -9.671  -5.955  1.000 13.565 0 292  THR A H    1 c 
ATOM   4470 H HA   . THR A 1 277 ? -32.864 -8.237  -3.910  1.000 13.704 0 292  THR A HA   1 c 
ATOM   4471 H HB   . THR A 1 277 ? -31.787 -7.192  -6.332  1.000 13.534 0 292  THR A HB   1 c 
ATOM   4472 H HG1  . THR A 1 277 ? -30.590 -7.320  -3.945  0.000 13.100 0 292  THR A HG1  1 c 
ATOM   4473 H HG21 . THR A 1 277 ? -31.718 -5.146  -5.101  1.000 14.426 0 292  THR A HG21 1 c 
ATOM   4474 H HG22 . THR A 1 277 ? -32.562 -5.851  -3.957  1.000 14.426 0 292  THR A HG22 1 c 
ATOM   4475 H HG23 . THR A 1 277 ? -33.199 -5.635  -5.394  1.000 14.428 0 292  THR A HG23 1 c 
ATOM   4476 N N    . PRO A 1 278 ? -35.262 -8.024  -4.844  1.000 15.808 0 293  PRO A N    1 ? 
ATOM   4477 C CA   . PRO A 1 278 ? -36.545 -7.908  -5.533  1.000 17.908 0 293  PRO A CA   1 ? 
ATOM   4478 C C    . PRO A 1 278 ? -36.589 -6.798  -6.567  1.000 15.603 0 293  PRO A C    1 ? 
ATOM   4479 O O    . PRO A 1 278 ? -36.031 -5.736  -6.362  1.000 18.137 0 293  PRO A O    1 ? 
ATOM   4480 C CB   . PRO A 1 278 ? -37.571 -7.674  -4.394  1.000 18.007 0 293  PRO A CB   1 ? 
ATOM   4481 C CG   . PRO A 1 278 ? -36.884 -8.195  -3.172  1.000 19.145 0 293  PRO A CG   1 ? 
ATOM   4482 C CD   . PRO A 1 278 ? -35.374 -7.990  -3.376  1.000 18.945 0 293  PRO A CD   1 ? 
ATOM   4483 H HA   . PRO A 1 278 ? -36.740 -8.774  -5.971  1.000 17.043 0 293  PRO A HA   1 c 
ATOM   4484 H HB2  . PRO A 1 278 ? -37.780 -6.715  -4.298  1.000 18.224 0 293  PRO A HB2  1 c 
ATOM   4485 H HB3  . PRO A 1 278 ? -38.407 -8.168  -4.566  1.000 18.237 0 293  PRO A HB3  1 c 
ATOM   4486 H HG2  . PRO A 1 278 ? -37.188 -7.710  -2.376  1.000 18.832 0 293  PRO A HG2  1 c 
ATOM   4487 H HG3  . PRO A 1 278 ? -37.083 -9.146  -3.048  1.000 18.832 0 293  PRO A HG3  1 c 
ATOM   4488 H HD2  . PRO A 1 278 ? -35.079 -7.125  -3.014  1.000 18.193 0 293  PRO A HD2  1 c 
ATOM   4489 H HD3  . PRO A 1 278 ? -34.858 -8.715  -2.959  1.000 18.144 0 293  PRO A HD3  1 c 
ATOM   4490 N N    . GLY A 1 279 ? -37.159 -7.103  -7.722  1.000 15.969 0 294  GLY A N    1 ? 
ATOM   4491 C CA   . GLY A 1 279 ? -37.346 -6.131  -8.770  1.000 17.149 0 294  GLY A CA   1 ? 
ATOM   4492 C C    . GLY A 1 279 ? -36.116 -5.934  -9.657  1.000 19.662 0 294  GLY A C    1 ? 
ATOM   4493 O O    . GLY A 1 279 ? -36.141 -5.016  -10.483 1.000 24.443 0 294  GLY A O    1 ? 
ATOM   4494 H H    . GLY A 1 279 ? -37.446 -7.959  -7.866  1.000 16.161 0 294  GLY A H    1 c 
ATOM   4495 H HA2  . GLY A 1 279 ? -38.103 -6.417  -9.329  1.000 17.381 0 294  GLY A HA2  1 c 
ATOM   4496 H HA3  . GLY A 1 279 ? -37.590 -5.267  -8.362  1.000 17.375 0 294  GLY A HA3  1 c 
ATOM   4497 N N    . ARG A 1 280 ? -35.088 -6.780  -9.518  1.000 14.857 0 295  ARG A N    1 ? 
ATOM   4498 C CA   . ARG A 1 280 ? -33.905 -6.704  -10.361 1.000 13.745 0 295  ARG A CA   1 ? 
ATOM   4499 C C    . ARG A 1 280 ? -33.863 -7.848  -11.359 1.000 13.800 0 295  ARG A C    1 ? 
ATOM   4500 O O    . ARG A 1 280 ? -34.484 -8.882  -11.183 1.000 14.648 0 295  ARG A O    1 ? 
ATOM   4501 C CB   . ARG A 1 280 ? -32.662 -6.737  -9.468  1.000 13.199 0 295  ARG A CB   1 ? 
ATOM   4502 C CG   . ARG A 1 280 ? -32.386 -5.453  -8.723  1.000 12.916 0 295  ARG A CG   1 ? 
ATOM   4503 C CD   . ARG A 1 280 ? -32.181 -4.240  -9.580  1.000 12.806 0 295  ARG A CD   1 ? 
ATOM   4504 N NE   . ARG A 1 280 ? -31.803 -3.049  -8.843  1.000 13.012 0 295  ARG A NE   1 ? 
ATOM   4505 C CZ   . ARG A 1 280 ? -31.353 -1.941  -9.367  1.000 12.449 0 295  ARG A CZ   1 ? 
ATOM   4506 N NH1  . ARG A 1 280 ? -31.349 -1.744  -10.661 1.000 12.954 0 295  ARG A NH1  1 ? 
ATOM   4507 N NH2  . ARG A 1 280 ? -30.920 -1.011  -8.548  1.000 13.567 0 295  ARG A NH2  1 ? 
ATOM   4508 H H    . ARG A 1 280 ? -35.127 -7.433  -8.881  1.000 15.605 0 295  ARG A H    1 c 
ATOM   4509 H HA   . ARG A 1 280 ? -33.930 -5.850  -10.856 1.000 13.936 0 295  ARG A HA   1 c 
ATOM   4510 H HB2  . ARG A 1 280 ? -32.767 -7.461  -8.815  1.000 13.278 0 295  ARG A HB2  1 c 
ATOM   4511 H HB3  . ARG A 1 280 ? -31.882 -6.950  -10.022 1.000 13.265 0 295  ARG A HB3  1 c 
ATOM   4512 H HG2  . ARG A 1 280 ? -33.135 -5.278  -8.111  1.000 12.955 0 295  ARG A HG2  1 c 
ATOM   4513 H HG3  . ARG A 1 280 ? -31.587 -5.579  -8.166  1.000 12.955 0 295  ARG A HG3  1 c 
ATOM   4514 H HD2  . ARG A 1 280 ? -31.486 -4.440  -10.240 1.000 12.867 0 295  ARG A HD2  1 c 
ATOM   4515 H HD3  . ARG A 1 280 ? -33.008 -4.057  -10.070 1.000 12.889 0 295  ARG A HD3  1 c 
ATOM   4516 H HE   . ARG A 1 280 ? -31.888 -3.073  -7.976  1.000 12.838 0 295  ARG A HE   1 c 
ATOM   4517 H HH11 . ARG A 1 280 ? -30.688 -1.282  -11.030 1.000 12.806 0 295  ARG A HH11 1 c 
ATOM   4518 H HH12 . ARG A 1 280 ? -32.004 -2.068  -11.163 1.000 12.799 0 295  ARG A HH12 1 c 
ATOM   4519 H HH21 . ARG A 1 280 ? -30.926 -0.165  -8.806  1.000 13.202 0 295  ARG A HH21 1 c 
ATOM   4520 H HH22 . ARG A 1 280 ? -30.624 -1.229  -7.744  1.000 13.166 0 295  ARG A HH22 1 c 
ATOM   4521 N N    . PRO A 1 281 ? -33.053 -7.691  -12.435 1.000 13.602 0 296  PRO A N    1 ? 
ATOM   4522 C CA   . PRO A 1 281 ? -32.852 -8.765  -13.389 1.000 15.200 0 296  PRO A CA   1 ? 
ATOM   4523 C C    . PRO A 1 281 ? -32.339 -10.041 -12.752 1.000 13.609 0 296  PRO A C    1 ? 
ATOM   4524 O O    . PRO A 1 281 ? -31.591 -10.008 -11.772 1.000 12.707 0 296  PRO A O    1 ? 
ATOM   4525 C CB   . PRO A 1 281 ? -31.788 -8.165  -14.329 1.000 15.962 0 296  PRO A CB   1 ? 
ATOM   4526 C CG   . PRO A 1 281 ? -31.909 -6.704  -14.191 1.000 16.118 0 296  PRO A CG   1 ? 
ATOM   4527 C CD   . PRO A 1 281 ? -32.326 -6.472  -12.775 1.000 14.280 0 296  PRO A CD   1 ? 
ATOM   4528 H HA   . PRO A 1 281 ? -33.691 -8.935  -13.886 1.000 14.701 0 296  PRO A HA   1 c 
ATOM   4529 H HB2  . PRO A 1 281 ? -30.885 -8.465  -14.071 1.000 15.813 0 296  PRO A HB2  1 c 
ATOM   4530 H HB3  . PRO A 1 281 ? -31.953 -8.441  -15.262 1.000 15.824 0 296  PRO A HB3  1 c 
ATOM   4531 H HG2  . PRO A 1 281 ? -31.051 -6.266  -14.374 1.000 15.644 0 296  PRO A HG2  1 c 
ATOM   4532 H HG3  . PRO A 1 281 ? -32.580 -6.350  -14.811 1.000 15.644 0 296  PRO A HG3  1 c 
ATOM   4533 H HD2  . PRO A 1 281 ? -31.548 -6.350  -12.193 1.000 14.454 0 296  PRO A HD2  1 c 
ATOM   4534 H HD3  . PRO A 1 281 ? -32.904 -5.681  -12.708 1.000 14.530 0 296  PRO A HD3  1 c 
ATOM   4535 N N    . ASP A 1 282 ? -32.724 -11.172 -13.325 1.000 14.004 0 297  ASP A N    1 ? 
ATOM   4536 C CA   . ASP A 1 282 ? -32.246 -12.463 -12.900 1.000 13.759 0 297  ASP A CA   1 ? 
ATOM   4537 C C    . ASP A 1 282 ? -30.738 -12.630 -13.184 1.000 11.398 0 297  ASP A C    1 ? 
ATOM   4538 O O    . ASP A 1 282 ? -30.182 -11.969 -14.091 1.000 12.310 0 297  ASP A O    1 ? 
ATOM   4539 C CB   . ASP A 1 282 ? -32.875 -13.592 -13.690 1.000 18.473 0 297  ASP A CB   1 ? 
ATOM   4540 C CG   . ASP A 1 282 ? -34.372 -13.816 -13.609 1.000 28.975 0 297  ASP A CG   1 ? 
ATOM   4541 O OD1  . ASP A 1 282 ? -34.974 -13.354 -12.620 1.000 32.915 0 297  ASP A OD1  1 ? 
ATOM   4542 O OD2  . ASP A 1 282 ? -34.889 -14.456 -14.566 1.000 31.803 0 297  ASP A OD2  1 ? 
ATOM   4543 H H    . ASP A 1 282 ? -33.315 -11.136 -14.020 1.000 13.952 0 297  ASP A H    1 c 
ATOM   4544 H HA   . ASP A 1 282 ? -32.424 -12.570 -11.940 1.000 14.052 0 297  ASP A HA   1 c 
ATOM   4545 H HB2  . ASP A 1 282 ? -32.655 -13.456 -14.635 1.000 19.156 0 297  ASP A HB2  1 c 
ATOM   4546 H HB3  . ASP A 1 282 ? -32.450 -14.428 -13.409 1.000 19.017 0 297  ASP A HB3  1 c 
ATOM   4547 N N    . PRO A 1 283 ? -30.063 -13.515 -12.435 1.000 11.744 0 298  PRO A N    1 ? 
ATOM   4548 C CA   . PRO A 1 283 ? -28.663 -13.829 -12.747 1.000 11.594 0 298  PRO A CA   1 ? 
ATOM   4549 C C    . PRO A 1 283 ? -28.374 -14.105 -14.216 1.000 11.741 0 298  PRO A C    1 ? 
ATOM   4550 O O    . PRO A 1 283 ? -27.459 -13.524 -14.796 1.000 11.431 0 298  PRO A O    1 ? 
ATOM   4551 C CB   . PRO A 1 283 ? -28.347 -14.981 -11.877 1.000 11.603 0 298  PRO A CB   1 ? 
ATOM   4552 C CG   . PRO A 1 283 ? -29.241 -14.791 -10.651 1.000 12.012 0 298  PRO A CG   1 ? 
ATOM   4553 C CD   . PRO A 1 283 ? -30.522 -14.212 -11.228 1.000 11.609 0 298  PRO A CD   1 ? 
ATOM   4554 H HA   . PRO A 1 283 ? -28.116 -13.057 -12.457 1.000 11.651 0 298  PRO A HA   1 c 
ATOM   4555 H HB2  . PRO A 1 283 ? -28.550 -15.832 -12.331 1.000 11.691 0 298  PRO A HB2  1 c 
ATOM   4556 H HB3  . PRO A 1 283 ? -27.395 -14.976 -11.621 1.000 11.691 0 298  PRO A HB3  1 c 
ATOM   4557 H HG2  . PRO A 1 283 ? -29.413 -15.647 -10.205 1.000 11.828 0 298  PRO A HG2  1 c 
ATOM   4558 H HG3  . PRO A 1 283 ? -28.834 -14.172 -10.010 1.000 11.828 0 298  PRO A HG3  1 c 
ATOM   4559 H HD2  . PRO A 1 283 ? -31.162 -14.923 -11.452 1.000 11.792 0 298  PRO A HD2  1 c 
ATOM   4560 H HD3  . PRO A 1 283 ? -30.940 -13.588 -10.595 1.000 11.764 0 298  PRO A HD3  1 c 
ATOM   4561 N N    A LEU A 1 284 ? -29.215 -14.871 -14.929 0.500 11.139 0 299  LEU A N    1 ? 
ATOM   4562 N N    B LEU A 1 284 ? -29.220 -14.967 -14.777 0.500 11.757 0 299  LEU A N    1 ? 
ATOM   4563 C CA   A LEU A 1 284 ? -28.911 -15.178 -16.329 0.500 11.245 0 299  LEU A CA   1 ? 
ATOM   4564 C CA   B LEU A 1 284 ? -29.043 -15.367 -16.148 0.500 12.394 0 299  LEU A CA   1 ? 
ATOM   4565 C C    A LEU A 1 284 ? -28.915 -13.916 -17.166 0.500 12.060 0 299  LEU A C    1 ? 
ATOM   4566 C C    B LEU A 1 284 ? -28.989 -14.133 -17.049 0.500 11.777 0 299  LEU A C    1 ? 
ATOM   4567 O O    A LEU A 1 284 ? -28.163 -13.657 -18.124 0.500 9.711  0 299  LEU A O    1 ? 
ATOM   4568 O O    B LEU A 1 284 ? -28.095 -14.156 -17.904 0.500 11.284 0 299  LEU A O    1 ? 
ATOM   4569 C CB   A LEU A 1 284 ? -29.925 -16.169 -16.906 0.500 11.675 0 299  LEU A CB   1 ? 
ATOM   4570 C CB   B LEU A 1 284 ? -30.132 -16.366 -16.543 0.500 13.438 0 299  LEU A CB   1 ? 
ATOM   4571 C CG   A LEU A 1 284 ? -29.663 -17.614 -16.491 0.500 12.126 0 299  LEU A CG   1 ? 
ATOM   4572 C CG   B LEU A 1 284 ? -29.954 -17.064 -17.891 0.500 14.511 0 299  LEU A CG   1 ? 
ATOM   4573 C CD1  A LEU A 1 284 ? -30.837 -18.561 -16.829 0.500 12.273 0 299  LEU A CD1  1 ? 
ATOM   4574 C CD1  B LEU A 1 284 ? -28.653 -17.842 -17.997 0.500 13.842 0 299  LEU A CD1  1 ? 
ATOM   4575 C CD2  A LEU A 1 284 ? -28.328 -18.121 -17.102 0.500 12.395 0 299  LEU A CD2  1 ? 
ATOM   4576 C CD2  B LEU A 1 284 ? -31.196 -17.932 -18.144 0.500 16.331 0 299  LEU A CD2  1 ? 
ATOM   4577 H H    A LEU A 1 284 ? -29.975 -15.207 -14.548 0.500 11.306 0 299  LEU A H    1 c 
ATOM   4578 H H    B LEU A 1 284 ? -29.915 -15.315 -14.296 0.500 11.891 0 299  LEU A H    1 c 
ATOM   4579 H HA   A LEU A 1 284 ? -28.009 -15.580 -16.371 0.500 11.440 0 299  LEU A HA   1 c 
ATOM   4580 H HA   B LEU A 1 284 ? -28.166 -15.822 -16.214 0.500 12.314 0 299  LEU A HA   1 c 
ATOM   4581 H HB2  A LEU A 1 284 ? -30.825 -15.910 -16.600 0.500 11.676 0 299  LEU A HB2  1 c 
ATOM   4582 H HB2  B LEU A 1 284 ? -30.181 -17.058 -15.843 0.500 13.442 0 299  LEU A HB2  1 c 
ATOM   4583 H HB3  A LEU A 1 284 ? -29.893 -16.111 -17.889 0.500 11.676 0 299  LEU A HB3  1 c 
ATOM   4584 H HB3  B LEU A 1 284 ? -30.995 -15.891 -16.551 0.500 13.429 0 299  LEU A HB3  1 c 
ATOM   4585 H HG   A LEU A 1 284 ? -29.555 -17.626 -15.505 0.500 12.116 0 299  LEU A HG   1 c 
ATOM   4586 H HG   B LEU A 1 284 ? -29.936 -16.362 -18.593 0.500 14.493 0 299  LEU A HG   1 c 
ATOM   4587 H HD11 A LEU A 1 284 ? -31.005 -18.541 -17.786 0.500 12.255 0 299  LEU A HD11 1 c 
ATOM   4588 H HD11 B LEU A 1 284 ? -27.901 -17.233 -17.902 0.500 14.044 0 299  LEU A HD11 1 c 
ATOM   4589 H HD12 A LEU A 1 284 ? -31.634 -18.273 -16.354 0.500 12.334 0 299  LEU A HD12 1 c 
ATOM   4590 H HD12 B LEU A 1 284 ? -28.607 -18.279 -18.863 0.500 14.069 0 299  LEU A HD12 1 c 
ATOM   4591 H HD13 A LEU A 1 284 ? -30.611 -19.467 -16.560 0.500 12.255 0 299  LEU A HD13 1 c 
ATOM   4592 H HD13 B LEU A 1 284 ? -28.617 -18.513 -17.295 0.500 14.044 0 299  LEU A HD13 1 c 
ATOM   4593 H HD21 A LEU A 1 284 ? -28.389 -18.108 -18.072 0.500 12.316 0 299  LEU A HD21 1 c 
ATOM   4594 H HD21 B LEU A 1 284 ? -31.990 -17.372 -18.138 0.500 15.790 0 299  LEU A HD21 1 c 
ATOM   4595 H HD22 A LEU A 1 284 ? -28.157 -19.028 -16.801 0.500 12.316 0 299  LEU A HD22 1 c 
ATOM   4596 H HD22 B LEU A 1 284 ? -31.269 -18.605 -17.447 0.500 15.790 0 299  LEU A HD22 1 c 
ATOM   4597 H HD23 A LEU A 1 284 ? -27.600 -17.543 -16.817 0.500 12.316 0 299  LEU A HD23 1 c 
ATOM   4598 H HD23 B LEU A 1 284 ? -31.116 -18.369 -19.008 0.500 15.837 0 299  LEU A HD23 1 c 
ATOM   4599 N N    . THR A 1 285 ? -29.884 -13.093 -16.890 1.000 12.161 0 300  THR A N    1 ? 
ATOM   4600 C CA   . THR A 1 285 ? -29.925 -11.869 -17.659 1.000 12.943 0 300  THR A CA   1 ? 
ATOM   4601 C C    . THR A 1 285 ? -28.578 -11.119 -17.526 1.000 11.767 0 300  THR A C    1 ? 
ATOM   4602 O O    . THR A 1 285 ? -28.030 -10.550 -18.478 1.000 12.089 0 300  THR A O    1 ? 
ATOM   4603 C CB   . THR A 1 285 ? -31.110 -10.982 -17.239 1.000 14.226 0 300  THR A CB   1 ? 
ATOM   4604 O OG1  . THR A 1 285 ? -32.302 -11.741 -17.492 1.000 16.733 0 300  THR A OG1  1 ? 
ATOM   4605 C CG2  . THR A 1 285 ? -31.161 -9.699  -18.015 1.000 15.119 0 300  THR A CG2  1 ? 
ATOM   4606 H H    . THR A 1 285 ? -30.512 -13.229 -16.240 1.000 12.202 0 300  THR A H    1 c 
ATOM   4607 H HA   . THR A 1 285 ? -30.050 -12.110 -18.604 1.000 12.764 0 300  THR A HA   1 c 
ATOM   4608 H HB   . THR A 1 285 ? -31.050 -10.778 -16.275 1.000 14.591 0 300  THR A HB   1 c 
ATOM   4609 H HG1  . THR A 1 285 ? -32.348 -11.937 -18.332 0.000 16.740 0 300  THR A HG1  1 c 
ATOM   4610 H HG21 . THR A 1 285 ? -32.004 -9.247  -17.840 1.000 14.859 0 300  THR A HG21 1 c 
ATOM   4611 H HG22 . THR A 1 285 ? -31.089 -9.891  -18.965 1.000 14.859 0 300  THR A HG22 1 c 
ATOM   4612 H HG23 . THR A 1 285 ? -30.426 -9.124  -17.744 1.000 14.899 0 300  THR A HG23 1 c 
ATOM   4613 N N    . LEU A 1 286 ? -28.091 -11.049 -16.289 1.000 11.539 0 301  LEU A N    1 ? 
ATOM   4614 C CA   . LEU A 1 286 ? -26.852 -10.332 -15.990 1.000 10.635 0 301  LEU A CA   1 ? 
ATOM   4615 C C    . LEU A 1 286 ? -25.624 -11.026 -16.598 1.000 9.201  0 301  LEU A C    1 ? 
ATOM   4616 O O    . LEU A 1 286 ? -24.801 -10.323 -17.180 1.000 9.396  0 301  LEU A O    1 ? 
ATOM   4617 C CB   . LEU A 1 286 ? -26.719 -10.174 -14.484 1.000 10.673 0 301  LEU A CB   1 ? 
ATOM   4618 C CG   . LEU A 1 286 ? -27.731 -9.191  -13.861 1.000 11.857 0 301  LEU A CG   1 ? 
ATOM   4619 C CD1  . LEU A 1 286 ? -27.809 -9.380  -12.362 1.000 11.998 0 301  LEU A CD1  1 ? 
ATOM   4620 C CD2  . LEU A 1 286 ? -27.337 -7.760  -14.201 1.000 13.280 0 301  LEU A CD2  1 ? 
ATOM   4621 H H    . LEU A 1 286 ? -28.544 -11.451 -15.604 1.000 11.393 0 301  LEU A H    1 c 
ATOM   4622 H HA   . LEU A 1 286 ? -26.920 -9.432  -16.397 1.000 10.561 0 301  LEU A HA   1 c 
ATOM   4623 H HB2  . LEU A 1 286 ? -26.843 -11.057 -14.066 1.000 10.923 0 301  LEU A HB2  1 c 
ATOM   4624 H HB3  . LEU A 1 286 ? -25.808 -9.857  -14.282 1.000 10.933 0 301  LEU A HB3  1 c 
ATOM   4625 H HG   . LEU A 1 286 ? -28.625 -9.373  -14.249 1.000 11.903 0 301  LEU A HG   1 c 
ATOM   4626 H HD11 . LEU A 1 286 ? -28.092 -10.288 -12.163 1.000 11.956 0 301  LEU A HD11 1 c 
ATOM   4627 H HD12 . LEU A 1 286 ? -28.451 -8.753  -11.988 1.000 11.956 0 301  LEU A HD12 1 c 
ATOM   4628 H HD13 . LEU A 1 286 ? -26.935 -9.220  -11.968 1.000 11.956 0 301  LEU A HD13 1 c 
ATOM   4629 H HD21 . LEU A 1 286 ? -27.413 -7.619  -15.159 1.000 12.810 0 301  LEU A HD21 1 c 
ATOM   4630 H HD22 . LEU A 1 286 ? -26.420 -7.600  -13.922 1.000 12.822 0 301  LEU A HD22 1 c 
ATOM   4631 H HD23 . LEU A 1 286 ? -27.927 -7.142  -13.737 1.000 12.833 0 301  LEU A HD23 1 c 
ATOM   4632 N N    . TYR A 1 287 ? -25.575 -12.354 -16.541 1.000 9.545  0 302  TYR A N    1 ? 
ATOM   4633 C CA   . TYR A 1 287 ? -24.455 -13.027 -17.203 1.000 9.387  0 302  TYR A CA   1 ? 
ATOM   4634 C C    . TYR A 1 287 ? -24.427 -12.710 -18.701 1.000 9.428  0 302  TYR A C    1 ? 
ATOM   4635 O O    . TYR A 1 287 ? -23.379 -12.470 -19.332 1.000 9.736  0 302  TYR A O    1 ? 
ATOM   4636 C CB   . TYR A 1 287 ? -24.494 -14.548 -17.038 1.000 9.573  0 302  TYR A CB   1 ? 
ATOM   4637 C CG   . TYR A 1 287 ? -24.312 -15.027 -15.613 1.000 9.802  0 302  TYR A CG   1 ? 
ATOM   4638 C CD1  . TYR A 1 287 ? -23.146 -14.779 -14.885 1.000 9.666  0 302  TYR A CD1  1 ? 
ATOM   4639 C CD2  . TYR A 1 287 ? -25.315 -15.741 -14.951 1.000 10.517 0 302  TYR A CD2  1 ? 
ATOM   4640 C CE1  . TYR A 1 287 ? -22.980 -15.201 -13.582 1.000 9.815  0 302  TYR A CE1  1 ? 
ATOM   4641 C CE2  . TYR A 1 287 ? -25.171 -16.154 -13.664 1.000 10.141 0 302  TYR A CE2  1 ? 
ATOM   4642 C CZ   . TYR A 1 287 ? -24.025 -15.858 -12.935 1.000 9.985  0 302  TYR A CZ   1 ? 
ATOM   4643 O OH   . TYR A 1 287 ? -23.930 -16.251 -11.647 1.000 11.032 0 302  TYR A OH   1 ? 
ATOM   4644 H H    . TYR A 1 287 ? -26.212 -12.841 -16.102 1.000 9.449  0 302  TYR A H    1 c 
ATOM   4645 H HA   . TYR A 1 287 ? -23.612 -12.692 -16.798 1.000 9.460  0 302  TYR A HA   1 c 
ATOM   4646 H HB2  . TYR A 1 287 ? -25.357 -14.876 -17.376 1.000 9.591  0 302  TYR A HB2  1 c 
ATOM   4647 H HB3  . TYR A 1 287 ? -23.786 -14.941 -17.596 1.000 9.583  0 302  TYR A HB3  1 c 
ATOM   4648 H HD1  . TYR A 1 287 ? -22.446 -14.299 -15.298 1.000 9.731  0 302  TYR A HD1  1 c 
ATOM   4649 H HD2  . TYR A 1 287 ? -26.122 -15.923 -15.401 1.000 10.270 0 302  TYR A HD2  1 c 
ATOM   4650 H HE1  . TYR A 1 287 ? -22.195 -14.982 -13.110 1.000 9.830  0 302  TYR A HE1  1 c 
ATOM   4651 H HE2  . TYR A 1 287 ? -25.884 -16.598 -13.240 1.000 10.221 0 302  TYR A HE2  1 c 
ATOM   4652 H HH   . TYR A 1 287 ? -24.210 -15.625 -11.129 0.000 11.030 0 302  TYR A HH   1 c 
ATOM   4653 N N    . HIS A 1 288 ? -25.624 -12.745 -19.330 1.000 10.019 0 303  HIS A N    1 ? 
ATOM   4654 C CA   . HIS A 1 288 ? -25.754 -12.447 -20.747 1.000 10.565 0 303  HIS A CA   1 ? 
ATOM   4655 C C    . HIS A 1 288 ? -25.429 -10.997 -21.057 1.000 9.899  0 303  HIS A C    1 ? 
ATOM   4656 O O    . HIS A 1 288 ? -24.853 -10.702 -22.089 1.000 10.590 0 303  HIS A O    1 ? 
ATOM   4657 C CB   . HIS A 1 288 ? -27.092 -12.964 -21.290 1.000 11.610 0 303  HIS A CB   1 ? 
ATOM   4658 C CG   . HIS A 1 288 ? -27.047 -14.452 -21.476 1.000 12.962 0 303  HIS A CG   1 ? 
ATOM   4659 N ND1  . HIS A 1 288 ? -26.365 -15.043 -22.531 1.000 15.466 0 303  HIS A ND1  1 ? 
ATOM   4660 C CD2  . HIS A 1 288 ? -27.486 -15.456 -20.735 1.000 15.797 0 303  HIS A CD2  1 ? 
ATOM   4661 C CE1  . HIS A 1 288 ? -26.455 -16.378 -22.411 1.000 15.620 0 303  HIS A CE1  1 ? 
ATOM   4662 N NE2  . HIS A 1 288 ? -27.159 -16.648 -21.334 1.000 15.121 0 303  HIS A NE2  1 ? 
ATOM   4663 H H    . HIS A 1 288 ? -26.374 -12.967 -18.856 1.000 10.008 0 303  HIS A H    1 c 
ATOM   4664 H HA   . HIS A 1 288 ? -25.061 -12.997 -21.191 1.000 10.517 0 303  HIS A HA   1 c 
ATOM   4665 H HB2  . HIS A 1 288 ? -27.807 -12.736 -20.657 1.000 11.635 0 303  HIS A HB2  1 c 
ATOM   4666 H HB3  . HIS A 1 288 ? -27.276 -12.534 -22.153 1.000 11.645 0 303  HIS A HB3  1 c 
ATOM   4667 H HD1  . HIS A 1 288 ? -25.918 -14.610 -23.155 0.000 15.460 0 303  HIS A HD1  1 c 
ATOM   4668 H HD2  . HIS A 1 288 ? -27.997 -15.383 -19.954 1.000 14.843 0 303  HIS A HD2  1 c 
ATOM   4669 H HE1  . HIS A 1 288 ? -26.100 -17.010 -23.013 1.000 15.445 0 303  HIS A HE1  1 c 
ATOM   4670 H HE2  . HIS A 1 288 ? -27.355 -17.451 -21.043 0.000 15.120 0 303  HIS A HE2  1 c 
ATOM   4671 N N    . LYS A 1 289 ? -25.727 -10.052 -20.148 1.000 9.841  0 304  LYS A N    1 ? 
ATOM   4672 C CA   . LYS A 1 289 ? -25.304 -8.690  -20.333 1.000 10.381 0 304  LYS A CA   1 ? 
ATOM   4673 C C    . LYS A 1 289 ? -23.763 -8.564  -20.309 1.000 9.464  0 304  LYS A C    1 ? 
ATOM   4674 O O    . LYS A 1 289 ? -23.152 -7.739  -21.012 1.000 10.065 0 304  LYS A O    1 ? 
ATOM   4675 C CB   . LYS A 1 289 ? -25.942 -7.803  -19.249 1.000 13.060 0 304  LYS A CB   1 ? 
ATOM   4676 C CG   . LYS A 1 289 ? -27.399 -7.476  -19.447 1.000 18.204 0 304  LYS A CG   1 ? 
ATOM   4677 C CD   . LYS A 1 289 ? -27.961 -6.594  -18.332 1.000 21.573 0 304  LYS A CD   1 ? 
ATOM   4678 C CE   . LYS A 1 289 ? -29.399 -6.205  -18.585 1.000 28.629 0 304  LYS A CE   1 ? 
ATOM   4679 N NZ   . LYS A 1 289 ? -29.524 -5.487  -19.853 1.000 34.760 0 304  LYS A NZ   1 ? 
ATOM   4680 H H    . LYS A 1 289 ? -26.211 -10.272 -19.404 1.000 10.022 0 304  LYS A H    1 c 
ATOM   4681 H HA   . LYS A 1 289 ? -25.629 -8.382  -21.217 1.000 10.587 0 304  LYS A HA   1 c 
ATOM   4682 H HB2  . LYS A 1 289 ? -25.842 -8.249  -18.381 1.000 13.346 0 304  LYS A HB2  1 c 
ATOM   4683 H HB3  . LYS A 1 289 ? -25.442 -6.959  -19.204 1.000 13.367 0 304  LYS A HB3  1 c 
ATOM   4684 H HG2  . LYS A 1 289 ? -27.502 -7.015  -20.308 1.000 17.648 0 304  LYS A HG2  1 c 
ATOM   4685 H HG3  . LYS A 1 289 ? -27.909 -8.311  -19.486 1.000 17.515 0 304  LYS A HG3  1 c 
ATOM   4686 H HD2  . LYS A 1 289 ? -27.904 -7.078  -17.479 1.000 22.172 0 304  LYS A HD2  1 c 
ATOM   4687 H HD3  . LYS A 1 289 ? -27.416 -5.781  -18.258 1.000 22.219 0 304  LYS A HD3  1 c 
ATOM   4688 H HE2  . LYS A 1 289 ? -29.952 -7.006  -18.619 1.000 27.980 0 304  LYS A HE2  1 c 
ATOM   4689 H HE3  . LYS A 1 289 ? -29.726 -5.640  -17.864 1.000 28.048 0 304  LYS A HE3  1 c 
ATOM   4690 H HZ1  . LYS A 1 289 ? -29.629 -6.078  -20.533 1.000 32.457 0 304  LYS A HZ1  1 c 
ATOM   4691 H HZ2  . LYS A 1 289 ? -28.785 -4.985  -20.005 1.000 32.511 0 304  LYS A HZ2  1 c 
ATOM   4692 H HZ3  . LYS A 1 289 ? -30.249 -4.944  -19.823 1.000 32.644 0 304  LYS A HZ3  1 c 
ATOM   4693 N N    . GLY A 1 290 ? -23.132 -9.352  -19.421 1.000 9.390  0 305  GLY A N    1 ? 
ATOM   4694 C CA   . GLY A 1 290 ? -21.662 -9.353  -19.354 1.000 8.873  0 305  GLY A CA   1 ? 
ATOM   4695 C C    . GLY A 1 290 ? -21.032 -9.828  -20.658 1.000 9.379  0 305  GLY A C    1 ? 
ATOM   4696 O O    . GLY A 1 290 ? -20.076 -9.239  -21.145 1.000 8.787  0 305  GLY A O    1 ? 
ATOM   4697 H H    . GLY A 1 290 ? -23.608 -9.884  -18.851 1.000 9.301  0 305  GLY A H    1 c 
ATOM   4698 H HA2  . GLY A 1 290 ? -21.349 -8.440  -19.151 1.000 9.109  0 305  GLY A HA2  1 c 
ATOM   4699 H HA3  . GLY A 1 290 ? -21.375 -9.941  -18.617 1.000 9.105  0 305  GLY A HA3  1 c 
ATOM   4700 N N    . ILE A 1 291 ? -21.594 -10.913 -21.223 1.000 8.678  0 306  ILE A N    1 ? 
ATOM   4701 C CA   . ILE A 1 291 ? -21.146 -11.385 -22.537 1.000 8.681  0 306  ILE A CA   1 ? 
ATOM   4702 C C    . ILE A 1 291 ? -21.394 -10.313 -23.617 1.000 8.548  0 306  ILE A C    1 ? 
ATOM   4703 O O    . ILE A 1 291 ? -20.590 -10.076 -24.512 1.000 9.483  0 306  ILE A O    1 ? 
ATOM   4704 C CB   . ILE A 1 291 ? -21.824 -12.748 -22.876 1.000 9.428  0 306  ILE A CB   1 ? 
ATOM   4705 C CG1  . ILE A 1 291 ? -21.263 -13.815 -21.958 1.000 9.726  0 306  ILE A CG1  1 ? 
ATOM   4706 C CG2  . ILE A 1 291 ? -21.665 -13.111 -24.356 1.000 9.822  0 306  ILE A CG2  1 ? 
ATOM   4707 C CD1  . ILE A 1 291 ? -22.128 -15.058 -21.856 1.000 10.530 0 306  ILE A CD1  1 ? 
ATOM   4708 H H    . ILE A 1 291 ? -22.258 -11.366 -20.787 1.000 8.864  0 306  ILE A H    1 c 
ATOM   4709 H HA   . ILE A 1 291 ? -20.183 -11.539 -22.485 1.000 8.794  0 306  ILE A HA   1 c 
ATOM   4710 H HB   . ILE A 1 291 ? -22.779 -12.663 -22.687 1.000 9.410  0 306  ILE A HB   1 c 
ATOM   4711 H HG12 . ILE A 1 291 ? -20.377 -14.076 -22.285 1.000 9.830  0 306  ILE A HG12 1 c 
ATOM   4712 H HG13 . ILE A 1 291 ? -21.151 -13.437 -21.063 1.000 9.814  0 306  ILE A HG13 1 c 
ATOM   4713 H HG21 . ILE A 1 291 ? -21.926 -14.037 -24.495 1.000 9.712  0 306  ILE A HG21 1 c 
ATOM   4714 H HG22 . ILE A 1 291 ? -20.737 -12.995 -24.622 1.000 9.706  0 306  ILE A HG22 1 c 
ATOM   4715 H HG23 . ILE A 1 291 ? -22.230 -12.535 -24.897 1.000 9.701  0 306  ILE A HG23 1 c 
ATOM   4716 H HD11 . ILE A 1 291 ? -23.020 -14.810 -21.547 1.000 10.285 0 306  ILE A HD11 1 c 
ATOM   4717 H HD12 . ILE A 1 291 ? -21.728 -15.682 -21.221 1.000 10.285 0 306  ILE A HD12 1 c 
ATOM   4718 H HD13 . ILE A 1 291 ? -22.196 -15.487 -22.730 1.000 10.282 0 306  ILE A HD13 1 c 
ATOM   4719 N N    . ALA A 1 292 ? -22.580 -9.672  -23.596 1.000 9.994  0 307  ALA A N    1 ? 
ATOM   4720 C CA   . ALA A 1 292 ? -22.888 -8.614  -24.543 1.000 10.786 0 307  ALA A CA   1 ? 
ATOM   4721 C C    . ALA A 1 292 ? -21.936 -7.416  -24.453 1.000 10.388 0 307  ALA A C    1 ? 
ATOM   4722 O O    . ALA A 1 292 ? -21.494 -6.926  -25.487 1.000 11.168 0 307  ALA A O    1 ? 
ATOM   4723 C CB   . ALA A 1 292 ? -24.323 -8.132  -24.381 1.000 11.056 0 307  ALA A CB   1 ? 
ATOM   4724 H H    . ALA A 1 292 ? -23.209 -9.907  -22.977 1.000 9.787  0 307  ALA A H    1 c 
ATOM   4725 H HA   . ALA A 1 292 ? -22.793 -9.000  -25.458 1.000 10.599 0 307  ALA A HA   1 c 
ATOM   4726 H HB1  . ALA A 1 292 ? -24.935 -8.873  -24.526 1.000 10.975 0 307  ALA A HB1  1 c 
ATOM   4727 H HB2  . ALA A 1 292 ? -24.451 -7.781  -23.484 1.000 10.975 0 307  ALA A HB2  1 c 
ATOM   4728 H HB3  . ALA A 1 292 ? -24.508 -7.432  -25.029 1.000 10.972 0 307  ALA A HB3  1 c 
ATOM   4729 N N    . SER A 1 293 ? -21.519 -7.068  -23.232 1.000 9.372  0 308  SER A N    1 ? 
ATOM   4730 C CA   . SER A 1 293 ? -20.522 -6.025  -23.014 1.000 9.397  0 308  SER A CA   1 ? 
ATOM   4731 C C    . SER A 1 293 ? -19.195 -6.398  -23.689 1.000 8.117  0 308  SER A C    1 ? 
ATOM   4732 O O    . SER A 1 293 ? -18.567 -5.605  -24.409 1.000 9.247  0 308  SER A O    1 ? 
ATOM   4733 C CB   . SER A 1 293 ? -20.318 -5.821  -21.571 1.000 9.939  0 308  SER A CB   1 ? 
ATOM   4734 O OG   . SER A 1 293 ? -19.301 -4.861  -21.338 1.000 10.346 0 308  SER A OG   1 ? 
ATOM   4735 H H    . SER A 1 293 ? -21.874 -7.492  -22.504 1.000 9.623  0 308  SER A H    1 c 
ATOM   4736 H HA   . SER A 1 293 ? -20.855 -5.181  -23.413 1.000 9.245  0 308  SER A HA   1 c 
ATOM   4737 H HB2  . SER A 1 293 ? -21.152 -5.517  -21.165 1.000 9.903  0 308  SER A HB2  1 c 
ATOM   4738 H HB3  . SER A 1 293 ? -20.066 -6.667  -21.156 1.000 9.897  0 308  SER A HB3  1 c 
ATOM   4739 H HG   . SER A 1 293 ? -19.207 -4.766  -20.503 0.000 10.350 0 308  SER A HG   1 c 
ATOM   4740 N N    . ALA A 1 294 ? -18.794 -7.678  -23.524 1.000 8.098  0 309  ALA A N    1 ? 
ATOM   4741 C CA   . ALA A 1 294 ? -17.544 -8.122  -24.124 1.000 8.433  0 309  ALA A CA   1 ? 
ATOM   4742 C C    . ALA A 1 294 ? -17.609 -8.098  -25.650 1.000 8.167  0 309  ALA A C    1 ? 
ATOM   4743 O O    . ALA A 1 294 ? -16.662 -7.725  -26.335 1.000 9.068  0 309  ALA A O    1 ? 
ATOM   4744 C CB   . ALA A 1 294 ? -17.133 -9.481  -23.622 1.000 8.462  0 309  ALA A CB   1 ? 
ATOM   4745 H H    . ALA A 1 294 ? -19.295 -8.266  -23.036 1.000 8.193  0 309  ALA A H    1 c 
ATOM   4746 H HA   . ALA A 1 294 ? -16.841 -7.473  -23.851 1.000 8.326  0 309  ALA A HA   1 c 
ATOM   4747 H HB1  . ALA A 1 294 ? -17.066 -9.465  -22.652 1.000 8.462  0 309  ALA A HB1  1 c 
ATOM   4748 H HB2  . ALA A 1 294 ? -17.794 -10.142 -23.887 1.000 8.455  0 309  ALA A HB2  1 c 
ATOM   4749 H HB3  . ALA A 1 294 ? -16.270 -9.721  -23.999 1.000 8.454  0 309  ALA A HB3  1 c 
ATOM   4750 N N    . LYS A 1 295 ? -18.747 -8.567  -26.192 1.000 9.243  0 310  LYS A N    1 ? 
ATOM   4751 C CA   . LYS A 1 295 ? -18.953 -8.523  -27.637 1.000 9.359  0 310  LYS A CA   1 ? 
ATOM   4752 C C    . LYS A 1 295 ? -18.942 -7.103  -28.186 1.000 10.329 0 310  LYS A C    1 ? 
ATOM   4753 O O    . LYS A 1 295 ? -18.378 -6.815  -29.253 1.000 11.951 0 310  LYS A O    1 ? 
ATOM   4754 C CB   . LYS A 1 295 ? -20.247 -9.234  -28.040 1.000 10.985 0 310  LYS A CB   1 ? 
ATOM   4755 C CG   . LYS A 1 295 ? -20.161 -10.754 -27.853 1.000 11.281 0 310  LYS A CG   1 ? 
ATOM   4756 C CD   . LYS A 1 295 ? -21.521 -11.421 -28.103 1.000 12.151 0 310  LYS A CD   1 ? 
ATOM   4757 C CE   . LYS A 1 295 ? -21.500 -12.911 -27.996 1.000 13.740 0 310  LYS A CE   1 ? 
ATOM   4758 N NZ   . LYS A 1 295 ? -20.832 -13.585 -29.100 1.000 17.762 0 310  LYS A NZ   1 ? 
ATOM   4759 H H    . LYS A 1 295 ? -19.398 -8.924  -25.659 1.000 9.001  0 310  LYS A H    1 c 
ATOM   4760 H HA   . LYS A 1 295 ? -18.205 -9.016  -28.061 1.000 9.780  0 310  LYS A HA   1 c 
ATOM   4761 H HB2  . LYS A 1 295 ? -20.988 -8.890  -27.497 1.000 10.657 0 310  LYS A HB2  1 c 
ATOM   4762 H HB3  . LYS A 1 295 ? -20.444 -9.042  -28.981 1.000 10.656 0 310  LYS A HB3  1 c 
ATOM   4763 H HG2  . LYS A 1 295 ? -19.501 -11.114 -28.482 1.000 11.423 0 310  LYS A HG2  1 c 
ATOM   4764 H HG3  . LYS A 1 295 ? -19.862 -10.949 -26.939 1.000 11.384 0 310  LYS A HG3  1 c 
ATOM   4765 H HD2  . LYS A 1 295 ? -22.168 -11.066 -27.455 1.000 12.297 0 310  LYS A HD2  1 c 
ATOM   4766 H HD3  . LYS A 1 295 ? -21.833 -11.172 -29.000 1.000 12.297 0 310  LYS A HD3  1 c 
ATOM   4767 H HE2  . LYS A 1 295 ? -21.056 -13.159 -27.166 1.000 14.158 0 310  LYS A HE2  1 c 
ATOM   4768 H HE3  . LYS A 1 295 ? -22.417 -13.235 -27.946 1.000 14.191 0 310  LYS A HE3  1 c 
ATOM   4769 H HZ1  . LYS A 1 295 ? -19.958 -13.347 -29.122 1.000 16.309 0 310  LYS A HZ1  1 c 
ATOM   4770 H HZ2  . LYS A 1 295 ? -21.223 -13.351 -29.883 1.000 16.386 0 310  LYS A HZ2  1 c 
ATOM   4771 H HZ3  . LYS A 1 295 ? -20.894 -14.482 -28.993 1.000 16.386 0 310  LYS A HZ3  1 c 
ATOM   4772 N N    . THR A 1 296 ? -19.592 -6.192  -27.477 1.000 9.829  0 311  THR A N    1 ? 
ATOM   4773 C CA   . THR A 1 296 ? -19.791 -4.821  -27.935 1.000 10.575 0 311  THR A CA   1 ? 
ATOM   4774 C C    . THR A 1 296 ? -18.522 -3.993  -27.859 1.000 10.498 0 311  THR A C    1 ? 
ATOM   4775 O O    . THR A 1 296 ? -18.186 -3.252  -28.789 1.000 11.351 0 311  THR A O    1 ? 
ATOM   4776 C CB   . THR A 1 296 ? -20.917 -4.185  -27.118 1.000 11.248 0 311  THR A CB   1 ? 
ATOM   4777 O OG1  . THR A 1 296 ? -22.098 -4.916  -27.480 1.000 14.322 0 311  THR A OG1  1 ? 
ATOM   4778 C CG2  . THR A 1 296 ? -21.096 -2.716  -27.426 1.000 11.651 0 311  THR A CG2  1 ? 
ATOM   4779 H H    . THR A 1 296 ? -19.936 -6.431  -26.665 1.000 10.119 0 311  THR A H    1 c 
ATOM   4780 H HA   . THR A 1 296 ? -20.079 -4.856  -28.874 1.000 10.555 0 311  THR A HA   1 c 
ATOM   4781 H HB   . THR A 1 296 ? -20.741 -4.300  -26.154 1.000 11.729 0 311  THR A HB   1 c 
ATOM   4782 H HG1  . THR A 1 296 ? -22.239 -4.838  -28.328 0.000 14.330 0 311  THR A HG1  1 c 
ATOM   4783 H HG21 . THR A 1 296 ? -21.959 -2.417  -27.092 1.000 11.528 0 311  THR A HG21 1 c 
ATOM   4784 H HG22 . THR A 1 296 ? -21.056 -2.580  -28.387 1.000 11.529 0 311  THR A HG22 1 c 
ATOM   4785 H HG23 . THR A 1 296 ? -20.389 -2.204  -26.997 1.000 11.524 0 311  THR A HG23 1 c 
ATOM   4786 N N    . TYR A 1 297 ? -17.801 -4.074  -26.725 1.000 8.933  0 312  TYR A N    1 ? 
ATOM   4787 C CA   . TYR A 1 297 ? -16.705 -3.148  -26.479 1.000 9.183  0 312  TYR A CA   1 ? 
ATOM   4788 C C    . TYR A 1 297 ? -15.321 -3.764  -26.640 1.000 9.028  0 312  TYR A C    1 ? 
ATOM   4789 O O    . TYR A 1 297 ? -14.350 -3.043  -26.770 1.000 10.744 0 312  TYR A O    1 ? 
ATOM   4790 C CB   . TYR A 1 297 ? -16.786 -2.558  -25.059 1.000 9.538  0 312  TYR A CB   1 ? 
ATOM   4791 C CG   . TYR A 1 297 ? -18.049 -1.723  -24.909 1.000 10.215 0 312  TYR A CG   1 ? 
ATOM   4792 C CD1  . TYR A 1 297 ? -18.134 -0.467  -25.456 1.000 10.650 0 312  TYR A CD1  1 ? 
ATOM   4793 C CD2  . TYR A 1 297 ? -19.154 -2.221  -24.218 1.000 9.362  0 312  TYR A CD2  1 ? 
ATOM   4794 C CE1  . TYR A 1 297 ? -19.311 0.253   -25.334 1.000 11.250 0 312  TYR A CE1  1 ? 
ATOM   4795 C CE2  . TYR A 1 297 ? -20.349 -1.515  -24.126 1.000 10.539 0 312  TYR A CE2  1 ? 
ATOM   4796 C CZ   . TYR A 1 297 ? -20.414 -0.272  -24.709 1.000 11.212 0 312  TYR A CZ   1 ? 
ATOM   4797 O OH   . TYR A 1 297 ? -21.555 0.495   -24.607 1.000 12.952 0 312  TYR A OH   1 ? 
ATOM   4798 H H    . TYR A 1 297 ? -18.002 -4.706  -26.096 1.000 9.342  0 312  TYR A H    1 c 
ATOM   4799 H HA   . TYR A 1 297 ? -16.783 -2.397  -27.125 1.000 9.199  0 312  TYR A HA   1 c 
ATOM   4800 H HB2  . TYR A 1 297 ? -16.797 -3.291  -24.405 1.000 9.606  0 312  TYR A HB2  1 c 
ATOM   4801 H HB3  . TYR A 1 297 ? -15.998 -1.992  -24.898 1.000 9.608  0 312  TYR A HB3  1 c 
ATOM   4802 H HD1  . TYR A 1 297 ? -17.403 -0.102  -25.928 1.000 10.675 0 312  TYR A HD1  1 c 
ATOM   4803 H HD2  . TYR A 1 297 ? -19.114 -3.094  -23.863 1.000 9.841  0 312  TYR A HD2  1 c 
ATOM   4804 H HE1  . TYR A 1 297 ? -19.371 1.107   -25.728 1.000 11.087 0 312  TYR A HE1  1 c 
ATOM   4805 H HE2  . TYR A 1 297 ? -21.090 -1.873  -23.667 1.000 10.420 0 312  TYR A HE2  1 c 
ATOM   4806 H HH   . TYR A 1 297 ? -22.057 0.366   -25.289 0.000 12.960 0 312  TYR A HH   1 c 
ATOM   4807 N N    . TYR A 1 298 ? -15.218 -5.102  -26.624 1.000 7.997  0 313  TYR A N    1 ? 
ATOM   4808 C CA   . TYR A 1 298 ? -13.927 -5.791  -26.545 1.000 7.634  0 313  TYR A CA   1 ? 
ATOM   4809 C C    . TYR A 1 298 ? -13.765 -6.895  -27.600 1.000 8.523  0 313  TYR A C    1 ? 
ATOM   4810 O O    . TYR A 1 298 ? -13.014 -7.855  -27.396 1.000 8.466  0 313  TYR A O    1 ? 
ATOM   4811 C CB   . TYR A 1 298 ? -13.705 -6.353  -25.134 1.000 7.850  0 313  TYR A CB   1 ? 
ATOM   4812 C CG   . TYR A 1 298 ? -13.752 -5.249  -24.069 1.000 8.064  0 313  TYR A CG   1 ? 
ATOM   4813 C CD1  . TYR A 1 298 ? -12.768 -4.284  -23.973 1.000 9.657  0 313  TYR A CD1  1 ? 
ATOM   4814 C CD2  . TYR A 1 298 ? -14.830 -5.154  -23.211 1.000 8.359  0 313  TYR A CD2  1 ? 
ATOM   4815 C CE1  . TYR A 1 298 ? -12.835 -3.277  -23.014 1.000 8.881  0 313  TYR A CE1  1 ? 
ATOM   4816 C CE2  . TYR A 1 298 ? -14.921 -4.145  -22.268 1.000 8.157  0 313  TYR A CE2  1 ? 
ATOM   4817 C CZ   . TYR A 1 298 ? -13.916 -3.210  -22.182 1.000 8.868  0 313  TYR A CZ   1 ? 
ATOM   4818 O OH   . TYR A 1 298 ? -13.955 -2.178  -21.274 1.000 8.415  0 313  TYR A OH   1 ? 
ATOM   4819 H H    . TYR A 1 298 ? -15.979 -5.608  -26.655 1.000 8.169  0 313  TYR A H    1 c 
ATOM   4820 H HA   . TYR A 1 298 ? -13.216 -5.118  -26.711 1.000 7.929  0 313  TYR A HA   1 c 
ATOM   4821 H HB2  . TYR A 1 298 ? -14.402 -7.020  -24.943 1.000 7.853  0 313  TYR A HB2  1 c 
ATOM   4822 H HB3  . TYR A 1 298 ? -12.828 -6.796  -25.101 1.000 7.849  0 313  TYR A HB3  1 c 
ATOM   4823 H HD1  . TYR A 1 298 ? -12.022 -4.324  -24.550 1.000 9.061  0 313  TYR A HD1  1 c 
ATOM   4824 H HD2  . TYR A 1 298 ? -15.525 -5.788  -23.272 1.000 8.252  0 313  TYR A HD2  1 c 
ATOM   4825 H HE1  . TYR A 1 298 ? -12.156 -2.627  -22.960 1.000 9.021  0 313  TYR A HE1  1 c 
ATOM   4826 H HE2  . TYR A 1 298 ? -15.662 -4.100  -21.688 1.000 8.367  0 313  TYR A HE2  1 c 
ATOM   4827 H HH   . TYR A 1 298 ? -14.349 -1.498  -21.618 0.000 8.420  0 313  TYR A HH   1 c 
ATOM   4828 N N    A ARG A 1 299 ? -14.562 -6.818  -28.680 0.500 8.253  0 314  ARG A N    1 ? 
ATOM   4829 N N    B ARG A 1 299 ? -14.423 -6.746  -28.749 0.500 8.767  0 314  ARG A N    1 ? 
ATOM   4830 C CA   A ARG A 1 299 ? -14.431 -7.658  -29.865 0.500 8.367  0 314  ARG A CA   1 ? 
ATOM   4831 C CA   B ARG A 1 299 ? -14.284 -7.668  -29.870 0.500 9.191  0 314  ARG A CA   1 ? 
ATOM   4832 C C    A ARG A 1 299 ? -14.707 -9.124  -29.549 0.500 8.316  0 314  ARG A C    1 ? 
ATOM   4833 C C    B ARG A 1 299 ? -14.544 -9.123  -29.472 0.500 8.744  0 314  ARG A C    1 ? 
ATOM   4834 O O    A ARG A 1 299 ? -14.362 -10.014 -30.310 0.500 8.881  0 314  ARG A O    1 ? 
ATOM   4835 O O    B ARG A 1 299 ? -13.975 -10.015 -30.122 0.500 8.532  0 314  ARG A O    1 ? 
ATOM   4836 C CB   A ARG A 1 299 ? -13.091 -7.479  -30.577 0.500 8.690  0 314  ARG A CB   1 ? 
ATOM   4837 C CB   B ARG A 1 299 ? -12.921 -7.529  -30.562 0.500 11.059 0 314  ARG A CB   1 ? 
ATOM   4838 C CG   A ARG A 1 299 ? -12.796 -6.023  -30.897 0.500 9.729  0 314  ARG A CG   1 ? 
ATOM   4839 C CG   B ARG A 1 299 ? -12.593 -6.123  -31.038 0.500 13.762 0 314  ARG A CG   1 ? 
ATOM   4840 C CD   A ARG A 1 299 ? -11.596 -5.835  -31.848 0.500 10.185 0 314  ARG A CD   1 ? 
ATOM   4841 C CD   B ARG A 1 299 ? -11.324 -6.070  -31.896 0.500 15.412 0 314  ARG A CD   1 ? 
ATOM   4842 N NE   A ARG A 1 299 ? -10.490 -6.761  -31.615 0.500 11.205 0 314  ARG A NE   1 ? 
ATOM   4843 N NE   B ARG A 1 299 ? -10.120 -6.396  -31.128 0.500 19.921 0 314  ARG A NE   1 ? 
ATOM   4844 C CZ   A ARG A 1 299 ? -9.297  -6.733  -32.214 0.500 12.345 0 314  ARG A CZ   1 ? 
ATOM   4845 C CZ   B ARG A 1 299 ? -8.959  -6.879  -31.589 0.500 21.827 0 314  ARG A CZ   1 ? 
ATOM   4846 N NH1  A ARG A 1 299 ? -8.299  -7.567  -31.837 0.500 12.202 0 314  ARG A NH1  1 ? 
ATOM   4847 N NH1  B ARG A 1 299 ? -8.743  -6.954  -32.903 0.500 23.365 0 314  ARG A NH1  1 ? 
ATOM   4848 N NH2  A ARG A 1 299 ? -9.084  -5.879  -33.200 0.500 12.169 0 314  ARG A NH2  1 ? 
ATOM   4849 N NH2  B ARG A 1 299 ? -8.018  -7.255  -30.714 0.500 17.492 0 314  ARG A NH2  1 ? 
ATOM   4850 H H    A ARG A 1 299 ? -15.230 -6.195  -28.678 0.500 8.333  0 314  ARG A H    1 c 
ATOM   4851 H H    B ARG A 1 299 ? -14.985 -6.032  -28.845 0.500 8.787  0 314  ARG A H    1 c 
ATOM   4852 H HA   A ARG A 1 299 ? -15.126 -7.363  -30.507 0.500 8.394  0 314  ARG A HA   1 c 
ATOM   4853 H HA   B ARG A 1 299 ? -14.969 -7.419  -30.541 0.500 9.339  0 314  ARG A HA   1 c 
ATOM   4854 H HB2  A ARG A 1 299 ? -12.374 -7.834  -30.008 0.500 8.838  0 314  ARG A HB2  1 c 
ATOM   4855 H HB2  B ARG A 1 299 ? -12.222 -7.819  -29.939 0.500 11.135 0 314  ARG A HB2  1 c 
ATOM   4856 H HB3  A ARG A 1 299 ? -13.099 -7.996  -31.411 0.500 8.840  0 314  ARG A HB3  1 c 
ATOM   4857 H HB3  B ARG A 1 299 ? -12.900 -8.134  -31.334 0.500 11.148 0 314  ARG A HB3  1 c 
ATOM   4858 H HG2  A ARG A 1 299 ? -13.592 -5.619  -31.307 0.500 9.579  0 314  ARG A HG2  1 c 
ATOM   4859 H HG2  B ARG A 1 299 ? -13.347 -5.776  -31.563 0.500 13.430 0 314  ARG A HG2  1 c 
ATOM   4860 H HG3  A ARG A 1 299 ? -12.616 -5.542  -30.061 0.500 9.579  0 314  ARG A HG3  1 c 
ATOM   4861 H HG3  B ARG A 1 299 ? -12.475 -5.538  -30.258 0.500 13.430 0 314  ARG A HG3  1 c 
ATOM   4862 H HD2  A ARG A 1 299 ? -11.911 -5.941  -32.769 0.500 10.313 0 314  ARG A HD2  1 c 
ATOM   4863 H HD2  B ARG A 1 299 ? -11.412 -6.703  -32.638 0.500 15.975 0 314  ARG A HD2  1 c 
ATOM   4864 H HD3  A ARG A 1 299 ? -11.267 -4.918  -31.754 0.500 10.313 0 314  ARG A HD3  1 c 
ATOM   4865 H HD3  B ARG A 1 299 ? -11.230 -5.173  -32.275 0.500 15.975 0 314  ARG A HD3  1 c 
ATOM   4866 H HE   A ARG A 1 299 ? -10.616 -7.393  -31.030 0.500 11.212 0 314  ARG A HE   1 c 
ATOM   4867 H HE   B ARG A 1 299 ? -10.158 -6.263  -30.268 0.500 19.167 0 314  ARG A HE   1 c 
ATOM   4868 H HH11 A ARG A 1 299 ? -7.517  -7.530  -32.248 0.500 12.246 0 314  ARG A HH11 1 c 
ATOM   4869 H HH11 B ARG A 1 299 ? -7.979  -7.282  -33.204 0.500 22.880 0 314  ARG A HH11 1 c 
ATOM   4870 H HH12 A ARG A 1 299 ? -8.434  -8.144  -31.181 0.500 12.246 0 314  ARG A HH12 1 c 
ATOM   4871 H HH12 B ARG A 1 299 ? -9.365  -6.677  -33.467 0.500 22.881 0 314  ARG A HH12 1 c 
ATOM   4872 H HH21 A ARG A 1 299 ? -8.296  -5.858  -33.600 0.500 12.223 0 314  ARG A HH21 1 c 
ATOM   4873 H HH21 B ARG A 1 299 ? -7.247  -7.573  -31.008 0.500 18.728 0 314  ARG A HH21 1 c 
ATOM   4874 H HH22 A ARG A 1 299 ? -9.731  -5.333  -33.455 0.500 12.223 0 314  ARG A HH22 1 c 
ATOM   4875 H HH22 B ARG A 1 299 ? -8.171  -7.184  -29.846 0.500 18.728 0 314  ARG A HH22 1 c 
ATOM   4876 N N    . ASP A 1 300 ? -15.380 -9.390  -28.447 1.000 8.436  0 315  ASP A N    1 ? 
ATOM   4877 C CA   . ASP A 1 300 ? -15.615 -10.752 -28.008 1.000 8.368  0 315  ASP A CA   1 ? 
ATOM   4878 C C    . ASP A 1 300 ? -14.292 -11.492 -27.762 1.000 8.183  0 315  ASP A C    1 ? 
ATOM   4879 O O    . ASP A 1 300 ? -14.185 -12.692 -28.032 1.000 9.088  0 315  ASP A O    1 ? 
ATOM   4880 C CB   . ASP A 1 300 ? -16.495 -11.512 -28.989 1.000 9.049  0 315  ASP A CB   1 ? 
ATOM   4881 C CG   . ASP A 1 300 ? -17.249 -12.664 -28.384 1.000 10.876 0 315  ASP A CG   1 ? 
ATOM   4882 O OD1  . ASP A 1 300 ? -17.314 -12.851 -27.141 1.000 10.451 0 315  ASP A OD1  1 ? 
ATOM   4883 O OD2  . ASP A 1 300 ? -17.936 -13.399 -29.178 1.000 12.533 0 315  ASP A OD2  1 ? 
ATOM   4884 H H    . ASP A 1 300 ? -15.770 -8.706  -27.985 1.000 8.458  0 315  ASP A H    1 c 
ATOM   4885 H HA   . ASP A 1 300 ? -16.102 -10.708 -27.155 1.000 8.490  0 315  ASP A HA   1 c 
ATOM   4886 H HB2  . ASP A 1 300 ? -17.147 -10.889 -29.372 1.000 9.272  0 315  ASP A HB2  1 c 
ATOM   4887 H HB3  . ASP A 1 300 ? -15.947 -11.861 -29.722 1.000 9.271  0 315  ASP A HB3  1 c 
ATOM   4888 N N    A GLU A 1 301 ? -13.311 -10.817 -27.144 0.500 8.362  0 316  GLU A N    1 ? 
ATOM   4889 N N    B GLU A 1 301 ? -13.310 -10.819 -27.150 0.500 7.311  0 316  GLU A N    1 ? 
ATOM   4890 C CA   A GLU A 1 301 ? -11.995 -11.392 -26.897 0.500 9.248  0 316  GLU A CA   1 ? 
ATOM   4891 C CA   B GLU A 1 301 ? -12.008 -11.417 -26.901 0.500 7.360  0 316  GLU A CA   1 ? 
ATOM   4892 C C    A GLU A 1 301 ? -11.773 -11.762 -25.428 0.500 8.284  0 316  GLU A C    1 ? 
ATOM   4893 C C    B GLU A 1 301 ? -11.760 -11.681 -25.415 0.500 7.327  0 316  GLU A C    1 ? 
ATOM   4894 O O    A GLU A 1 301 ? -10.660 -12.130 -25.062 0.500 7.770  0 316  GLU A O    1 ? 
ATOM   4895 O O    B GLU A 1 301 ? -10.614 -11.884 -25.019 0.500 6.932  0 316  GLU A O    1 ? 
ATOM   4896 C CB   A GLU A 1 301 ? -10.882 -10.452 -27.354 0.500 11.348 0 316  GLU A CB   1 ? 
ATOM   4897 C CB   B GLU A 1 301 ? -10.915 -10.574 -27.557 0.500 7.375  0 316  GLU A CB   1 ? 
ATOM   4898 C CG   A GLU A 1 301 ? -10.881 -10.157 -28.844 0.500 13.413 0 316  GLU A CG   1 ? 
ATOM   4899 C CG   B GLU A 1 301 ? -10.912 -10.658 -29.071 0.500 7.649  0 316  GLU A CG   1 ? 
ATOM   4900 C CD   A GLU A 1 301 ? -10.244 -11.191 -29.725 0.500 16.198 0 316  GLU A CD   1 ? 
ATOM   4901 C CD   B GLU A 1 301 ? -9.900  -9.737  -29.717 0.500 8.475  0 316  GLU A CD   1 ? 
ATOM   4902 O OE1  A GLU A 1 301 ? -10.093 -10.894 -30.950 0.500 19.886 0 316  GLU A OE1  1 ? 
ATOM   4903 O OE1  B GLU A 1 301 ? -9.972  -8.550  -29.401 0.500 9.433  0 316  GLU A OE1  1 ? 
ATOM   4904 O OE2  A GLU A 1 301 ? -9.873  -12.256 -29.168 0.500 16.830 0 316  GLU A OE2  1 ? 
ATOM   4905 O OE2  B GLU A 1 301 ? -9.192  -10.140 -30.629 0.500 11.123 0 316  GLU A OE2  1 ? 
ATOM   4906 H H    A GLU A 1 301 ? -13.472 -9.964  -26.860 0.500 8.509  0 316  GLU A H    1 c 
ATOM   4907 H H    B GLU A 1 301 ? -13.459 -9.960  -26.874 0.500 7.532  0 316  GLU A H    1 c 
ATOM   4908 H HA   A GLU A 1 301 ? -11.917 -12.221 -27.433 0.500 9.225  0 316  GLU A HA   1 c 
ATOM   4909 H HA   B GLU A 1 301 ? -11.988 -12.295 -27.359 0.500 7.362  0 316  GLU A HA   1 c 
ATOM   4910 H HB2  A GLU A 1 301 ? -10.965 -9.606  -26.866 0.500 11.251 0 316  GLU A HB2  1 c 
ATOM   4911 H HB2  B GLU A 1 301 ? -11.034 -9.639  -27.289 0.500 7.439  0 316  GLU A HB2  1 c 
ATOM   4912 H HB3  A GLU A 1 301 ? -10.019 -10.848 -27.116 0.500 11.236 0 316  GLU A HB3  1 c 
ATOM   4913 H HB3  B GLU A 1 301 ? -10.045 -10.870 -27.222 0.500 7.441  0 316  GLU A HB3  1 c 
ATOM   4914 H HG2  A GLU A 1 301 ? -11.809 -10.037 -29.139 0.500 13.492 0 316  GLU A HG2  1 c 
ATOM   4915 H HG2  B GLU A 1 301 ? -10.714 -11.580 -29.342 0.500 7.766  0 316  GLU A HG2  1 c 
ATOM   4916 H HG3  A GLU A 1 301 ? -10.421 -9.304  -28.994 0.500 13.492 0 316  GLU A HG3  1 c 
ATOM   4917 H HG3  B GLU A 1 301 ? -11.804 -10.430 -29.408 0.500 7.766  0 316  GLU A HG3  1 c 
ATOM   4918 N N    . HIS A 1 302 ? -12.831 -11.729 -24.597 1.000 7.255  0 317  HIS A N    1 ? 
ATOM   4919 C CA   . HIS A 1 302 ? -12.715 -12.022 -23.163 1.000 7.601  0 317  HIS A CA   1 ? 
ATOM   4920 C C    . HIS A 1 302 ? -13.221 -13.435 -22.851 1.000 7.339  0 317  HIS A C    1 ? 
ATOM   4921 O O    . HIS A 1 302 ? -14.195 -13.883 -23.459 1.000 7.982  0 317  HIS A O    1 ? 
ATOM   4922 C CB   . HIS A 1 302 ? -13.481 -10.978 -22.341 1.000 6.905  0 317  HIS A CB   1 ? 
ATOM   4923 C CG   . HIS A 1 302 ? -12.932 -9.605  -22.354 1.000 6.496  0 317  HIS A CG   1 ? 
ATOM   4924 N ND1  . HIS A 1 302 ? -13.446 -8.630  -21.526 1.000 7.700  0 317  HIS A ND1  1 ? 
ATOM   4925 C CD2  . HIS A 1 302 ? -11.974 -9.056  -23.108 1.000 6.563  0 317  HIS A CD2  1 ? 
ATOM   4926 C CE1  . HIS A 1 302 ? -12.756 -7.520  -21.786 1.000 7.205  0 317  HIS A CE1  1 ? 
ATOM   4927 N NE2  . HIS A 1 302 ? -11.820 -7.713  -22.745 1.000 7.240  0 317  HIS A NE2  1 ? 
ATOM   4928 H H    . HIS A 1 302 ? -13.660 -11.550 -24.935 1.000 7.534  0 317  HIS A H    1 c 
ATOM   4929 H HA   . HIS A 1 302 ? -11.762 -11.972 -22.903 1.000 7.361  0 317  HIS A HA   1 c 
ATOM   4930 H HB2  . HIS A 1 302 ? -14.406 -10.947 -22.669 1.000 6.957  0 317  HIS A HB2  1 c 
ATOM   4931 H HB3  . HIS A 1 302 ? -13.525 -11.287 -21.411 1.000 6.965  0 317  HIS A HB3  1 c 
ATOM   4932 H HD1  . HIS A 1 302 ? -14.106 -8.744  -20.953 0.000 7.700  0 317  HIS A HD1  1 c 
ATOM   4933 H HD2  . HIS A 1 302 ? -11.455 -9.496  -23.751 1.000 6.717  0 317  HIS A HD2  1 c 
ATOM   4934 H HE1  . HIS A 1 302 ? -12.910 -6.705  -21.339 1.000 7.317  0 317  HIS A HE1  1 c 
ATOM   4935 H HE2  . HIS A 1 302 ? -11.270 -7.100  -23.050 0.000 7.240  0 317  HIS A HE2  1 c 
ATOM   4936 N N    . ILE A 1 303 ? -12.556 -14.102 -21.916 1.000 7.619  0 318  ILE A N    1 ? 
ATOM   4937 C CA   . ILE A 1 303 ? -12.891 -15.482 -21.567 1.000 7.657  0 318  ILE A CA   1 ? 
ATOM   4938 C C    . ILE A 1 303 ? -13.853 -15.544 -20.385 1.000 8.232  0 318  ILE A C    1 ? 
ATOM   4939 O O    . ILE A 1 303 ? -14.785 -16.377 -20.345 1.000 8.587  0 318  ILE A O    1 ? 
ATOM   4940 C CB   . ILE A 1 303 ? -11.615 -16.274 -21.228 1.000 9.524  0 318  ILE A CB   1 ? 
ATOM   4941 C CG1  . ILE A 1 303 ? -10.574 -16.246 -22.320 1.000 10.311 0 318  ILE A CG1  1 ? 
ATOM   4942 C CG2  . ILE A 1 303 ? -11.975 -17.728 -20.917 1.000 11.968 0 318  ILE A CG2  1 ? 
ATOM   4943 C CD1  . ILE A 1 303 ? -11.059 -16.930 -23.576 1.000 14.481 0 318  ILE A CD1  1 ? 
ATOM   4944 H H    . ILE A 1 303 ? -11.860 -13.697 -21.485 1.000 7.565  0 318  ILE A H    1 c 
ATOM   4945 H HA   . ILE A 1 303 ? -13.320 -15.903 -22.336 1.000 8.131  0 318  ILE A HA   1 c 
ATOM   4946 H HB   . ILE A 1 303 ? -11.220 -15.879 -20.424 1.000 9.688  0 318  ILE A HB   1 c 
ATOM   4947 H HG12 . ILE A 1 303 ? -10.348 -15.316 -22.527 1.000 10.930 0 318  ILE A HG12 1 c 
ATOM   4948 H HG13 . ILE A 1 303 ? -9.763  -16.694 -22.003 1.000 10.949 0 318  ILE A HG13 1 c 
ATOM   4949 H HG21 . ILE A 1 303 ? -11.178 -18.282 -20.968 1.000 11.180 0 318  ILE A HG21 1 c 
ATOM   4950 H HG22 . ILE A 1 303 ? -12.628 -18.044 -21.561 1.000 11.186 0 318  ILE A HG22 1 c 
ATOM   4951 H HG23 . ILE A 1 303 ? -12.351 -17.788 -20.024 1.000 11.172 0 318  ILE A HG23 1 c 
ATOM   4952 H HD11 . ILE A 1 303 ? -11.184 -17.883 -23.412 1.000 13.041 0 318  ILE A HD11 1 c 
ATOM   4953 H HD12 . ILE A 1 303 ? -10.391 -16.810 -24.278 1.000 13.050 0 318  ILE A HD12 1 c 
ATOM   4954 H HD13 . ILE A 1 303 ? -11.903 -16.537 -23.866 1.000 12.964 0 318  ILE A HD13 1 c 
ATOM   4955 N N    A TYR A 1 304 ? -13.640 -14.732 -19.333 0.500 7.537  0 319  TYR A N    1 ? 
ATOM   4956 N N    B TYR A 1 304 ? -13.670 -14.658 -19.422 0.500 8.391  0 319  TYR A N    1 ? 
ATOM   4957 C CA   A TYR A 1 304 ? -14.395 -14.860 -18.100 0.500 7.723  0 319  TYR A CA   1 ? 
ATOM   4958 C CA   B TYR A 1 304 ? -14.349 -14.800 -18.170 0.500 8.688  0 319  TYR A CA   1 ? 
ATOM   4959 C C    A TYR A 1 304 ? -15.899 -14.610 -18.286 0.500 8.358  0 319  TYR A C    1 ? 
ATOM   4960 C C    B TYR A 1 304 ? -15.852 -14.568 -18.247 0.500 9.015  0 319  TYR A C    1 ? 
ATOM   4961 O O    A TYR A 1 304 ? -16.708 -15.231 -17.596 0.500 7.828  0 319  TYR A O    1 ? 
ATOM   4962 O O    B TYR A 1 304 ? -16.525 -15.156 -17.387 0.500 8.447  0 319  TYR A O    1 ? 
ATOM   4963 C CB   A TYR A 1 304 ? -13.809 -14.077 -16.903 0.500 7.303  0 319  TYR A CB   1 ? 
ATOM   4964 C CB   B TYR A 1 304 ? -13.687 -13.914 -17.123 0.500 9.224  0 319  TYR A CB   1 ? 
ATOM   4965 C CG   A TYR A 1 304 ? -12.707 -14.798 -16.135 0.500 7.962  0 319  TYR A CG   1 ? 
ATOM   4966 C CG   B TYR A 1 304 ? -12.372 -14.472 -16.611 0.500 10.282 0 319  TYR A CG   1 ? 
ATOM   4967 C CD1  A TYR A 1 304 ? -13.069 -15.809 -15.279 0.500 8.477  0 319  TYR A CD1  1 ? 
ATOM   4968 C CD1  B TYR A 1 304 ? -11.878 -15.698 -17.032 0.500 11.365 0 319  TYR A CD1  1 ? 
ATOM   4969 C CD2  A TYR A 1 304 ? -11.357 -14.514 -16.286 0.500 8.683  0 319  TYR A CD2  1 ? 
ATOM   4970 C CD2  B TYR A 1 304 ? -11.600 -13.744 -15.737 0.500 11.363 0 319  TYR A CD2  1 ? 
ATOM   4971 C CE1  A TYR A 1 304 ? -12.134 -16.511 -14.556 0.500 9.574  0 319  TYR A CE1  1 ? 
ATOM   4972 C CE1  B TYR A 1 304 ? -10.698 -16.208 -16.515 0.500 12.046 0 319  TYR A CE1  1 ? 
ATOM   4973 C CE2  A TYR A 1 304 ? -10.399 -15.245 -15.601 0.500 8.804  0 319  TYR A CE2  1 ? 
ATOM   4974 C CE2  B TYR A 1 304 ? -10.422 -14.241 -15.222 0.500 11.028 0 319  TYR A CE2  1 ? 
ATOM   4975 C CZ   A TYR A 1 304 ? -10.812 -16.270 -14.765 0.500 9.040  0 319  TYR A CZ   1 ? 
ATOM   4976 C CZ   B TYR A 1 304 ? -10.009 -15.504 -15.559 0.500 12.533 0 319  TYR A CZ   1 ? 
ATOM   4977 O OH   A TYR A 1 304 ? -10.038 -17.069 -13.970 0.500 13.216 0 319  TYR A OH   1 ? 
ATOM   4978 O OH   B TYR A 1 304 ? -8.891  -16.004 -14.976 0.500 14.659 0 319  TYR A OH   1 ? 
ATOM   4979 H H    A TYR A 1 304 ? -13.002 -14.081 -19.392 0.500 7.737  0 319  TYR A H    1 c 
ATOM   4980 H H    B TYR A 1 304 ? -13.111 -13.947 -19.547 0.500 8.406  0 319  TYR A H    1 c 
ATOM   4981 H HA   A TYR A 1 304 ? -14.317 -15.818 -17.846 0.500 7.727  0 319  TYR A HA   1 c 
ATOM   4982 H HA   B TYR A 1 304 ? -14.217 -15.741 -17.875 0.500 8.781  0 319  TYR A HA   1 c 
ATOM   4983 H HB2  A TYR A 1 304 ? -13.454 -13.223 -17.235 0.500 7.548  0 319  TYR A HB2  1 c 
ATOM   4984 H HB2  B TYR A 1 304 ? -13.531 -13.027 -17.512 0.500 9.321  0 319  TYR A HB2  1 c 
ATOM   4985 H HB3  A TYR A 1 304 ? -14.542 -13.870 -16.281 0.500 7.544  0 319  TYR A HB3  1 c 
ATOM   4986 H HB3  B TYR A 1 304 ? -14.305 -13.809 -16.366 0.500 9.326  0 319  TYR A HB3  1 c 
ATOM   4987 H HD1  A TYR A 1 304 ? -13.984 -16.009 -15.162 0.500 8.603  0 319  TYR A HD1  1 c 
ATOM   4988 H HD1  B TYR A 1 304 ? -12.390 -16.225 -17.624 0.500 11.259 0 319  TYR A HD1  1 c 
ATOM   4989 H HD2  A TYR A 1 304 ? -11.087 -13.846 -16.894 0.500 8.536  0 319  TYR A HD2  1 c 
ATOM   4990 H HD2  B TYR A 1 304 ? -11.915 -12.911 -15.433 0.500 11.034 0 319  TYR A HD2  1 c 
ATOM   4991 H HE1  A TYR A 1 304 ? -12.402 -17.213 -13.988 0.500 9.188  0 319  TYR A HE1  1 c 
ATOM   4992 H HE1  B TYR A 1 304 ? -10.425 -17.077 -16.742 0.500 11.995 0 319  TYR A HE1  1 c 
ATOM   4993 H HE2  A TYR A 1 304 ? -9.482  -15.058 -15.711 0.500 8.844  0 319  TYR A HE2  1 c 
ATOM   4994 H HE2  B TYR A 1 304 ? -9.958  -13.757 -14.560 0.500 11.452 0 319  TYR A HE2  1 c 
ATOM   4995 H HH   A TYR A 1 304 ? -9.859  -17.803 -14.377 0.000 13.230 0 319  TYR A HH   1 c 
ATOM   4996 H HH   B TYR A 1 304 ? -8.199  -15.774 -15.425 0.000 14.650 0 319  TYR A HH   1 c 
ATOM   4997 N N    . PRO A 1 305 ? -16.416 -13.772 -19.185 1.000 8.623  0 320  PRO A N    1 ? 
ATOM   4998 C CA   . PRO A 1 305 ? -17.887 -13.663 -19.255 1.000 8.542  0 320  PRO A CA   1 ? 
ATOM   4999 C C    . PRO A 1 305 ? -18.552 -15.018 -19.471 1.000 8.763  0 320  PRO A C    1 ? 
ATOM   5000 O O    . PRO A 1 305 ? -19.578 -15.308 -18.872 1.000 9.104  0 320  PRO A O    1 ? 
ATOM   5001 C CB   . PRO A 1 305 ? -18.134 -12.665 -20.363 1.000 9.653  0 320  PRO A CB   1 ? 
ATOM   5002 C CG   . PRO A 1 305 ? -16.857 -11.766 -20.296 1.000 10.098 0 320  PRO A CG   1 ? 
ATOM   5003 C CD   . PRO A 1 305 ? -15.725 -12.826 -20.067 1.000 9.229  0 320  PRO A CD   1 ? 
ATOM   5004 H HA   . PRO A 1 305 ? -18.208 -13.279 -18.403 1.000 8.834  0 320  PRO A HA   1 c 
ATOM   5005 H HB2  . PRO A 1 305 ? -18.208 -13.114 -21.238 1.000 9.476  0 320  PRO A HB2  1 c 
ATOM   5006 H HB3  . PRO A 1 305 ? -18.950 -12.138 -20.193 1.000 9.480  0 320  PRO A HB3  1 c 
ATOM   5007 H HG2  . PRO A 1 305 ? -16.720 -11.275 -21.133 1.000 9.791  0 320  PRO A HG2  1 c 
ATOM   5008 H HG3  . PRO A 1 305 ? -16.905 -11.131 -19.551 1.000 9.790  0 320  PRO A HG3  1 c 
ATOM   5009 H HD2  . PRO A 1 305 ? -15.454 -13.250 -20.911 1.000 9.246  0 320  PRO A HD2  1 c 
ATOM   5010 H HD3  . PRO A 1 305 ? -14.945 -12.424 -19.627 1.000 9.232  0 320  PRO A HD3  1 c 
ATOM   5011 N N    . TYR A 1 306 ? -17.937 -15.868 -20.292 1.000 7.932  0 321  TYR A N    1 ? 
ATOM   5012 C CA   . TYR A 1 306 ? -18.434 -17.223 -20.511 1.000 8.412  0 321  TYR A CA   1 ? 
ATOM   5013 C C    . TYR A 1 306 ? -18.208 -18.125 -19.322 1.000 9.235  0 321  TYR A C    1 ? 
ATOM   5014 O O    . TYR A 1 306 ? -19.039 -18.995 -19.051 1.000 9.346  0 321  TYR A O    1 ? 
ATOM   5015 C CB   . TYR A 1 306 ? -17.813 -17.803 -21.781 1.000 9.242  0 321  TYR A CB   1 ? 
ATOM   5016 C CG   . TYR A 1 306 ? -18.131 -16.977 -23.009 1.000 8.699  0 321  TYR A CG   1 ? 
ATOM   5017 C CD1  . TYR A 1 306 ? -19.384 -17.035 -23.629 1.000 9.547  0 321  TYR A CD1  1 ? 
ATOM   5018 C CD2  . TYR A 1 306 ? -17.186 -16.103 -23.574 1.000 9.088  0 321  TYR A CD2  1 ? 
ATOM   5019 C CE1  . TYR A 1 306 ? -19.688 -16.255 -24.728 1.000 10.124 0 321  TYR A CE1  1 ? 
ATOM   5020 C CE2  . TYR A 1 306 ? -17.501 -15.318 -24.663 1.000 8.501  0 321  TYR A CE2  1 ? 
ATOM   5021 C CZ   . TYR A 1 306 ? -18.735 -15.403 -25.272 1.000 9.646  0 321  TYR A CZ   1 ? 
ATOM   5022 O OH   . TYR A 1 306 ? -19.092 -14.635 -26.370 1.000 11.263 0 321  TYR A OH   1 ? 
ATOM   5023 H H    . TYR A 1 306 ? -17.184 -15.599 -20.734 1.000 8.249  0 321  TYR A H    1 c 
ATOM   5024 H HA   . TYR A 1 306 ? -19.415 -17.162 -20.659 1.000 8.617  0 321  TYR A HA   1 c 
ATOM   5025 H HB2  . TYR A 1 306 ? -16.840 -17.834 -21.664 1.000 9.001  0 321  TYR A HB2  1 c 
ATOM   5026 H HB3  . TYR A 1 306 ? -18.146 -18.719 -21.910 1.000 8.938  0 321  TYR A HB3  1 c 
ATOM   5027 H HD1  . TYR A 1 306 ? -20.046 -17.608 -23.277 1.000 9.472  0 321  TYR A HD1  1 c 
ATOM   5028 H HD2  . TYR A 1 306 ? -16.333 -16.023 -23.177 1.000 8.878  0 321  TYR A HD2  1 c 
ATOM   5029 H HE1  . TYR A 1 306 ? -20.540 -16.317 -25.125 1.000 9.861  0 321  TYR A HE1  1 c 
ATOM   5030 H HE2  . TYR A 1 306 ? -16.848 -14.743 -25.023 1.000 8.923  0 321  TYR A HE2  1 c 
ATOM   5031 H HH   . TYR A 1 306 ? -19.413 -13.883 -26.108 0.000 11.260 0 321  TYR A HH   1 c 
ATOM   5032 N N    A MET A 1 307 ? -17.067 -17.970 -18.627 0.250 7.917  0 322  MET A N    1 ? 
ATOM   5033 N N    B MET A 1 307 ? -17.103 -17.956 -18.591 0.250 8.981  0 322  MET A N    1 ? 
ATOM   5034 N N    C MET A 1 307 ? -17.064 -17.946 -18.685 0.500 8.974  0 322  MET A N    1 ? 
ATOM   5035 C CA   A MET A 1 307 ? -16.800 -18.735 -17.414 0.250 7.261  0 322  MET A CA   1 ? 
ATOM   5036 C CA   B MET A 1 307 ? -16.856 -18.792 -17.427 0.250 9.006  0 322  MET A CA   1 ? 
ATOM   5037 C CA   C MET A 1 307 ? -16.758 -18.689 -17.485 0.500 9.189  0 322  MET A CA   1 ? 
ATOM   5038 C C    A MET A 1 307 ? -17.853 -18.464 -16.342 0.250 7.697  0 322  MET A C    1 ? 
ATOM   5039 C C    B MET A 1 307 ? -17.818 -18.463 -16.282 0.250 8.571  0 322  MET A C    1 ? 
ATOM   5040 C C    C MET A 1 307 ? -17.786 -18.450 -16.364 0.500 8.704  0 322  MET A C    1 ? 
ATOM   5041 O O    A MET A 1 307 ? -18.364 -19.388 -15.708 0.250 7.724  0 322  MET A O    1 ? 
ATOM   5042 O O    B MET A 1 307 ? -18.270 -19.353 -15.558 0.250 8.284  0 322  MET A O    1 ? 
ATOM   5043 O O    C MET A 1 307 ? -18.282 -19.394 -15.752 0.500 8.801  0 322  MET A O    1 ? 
ATOM   5044 C CB   A MET A 1 307 ? -15.483 -18.383 -16.714 0.250 6.434  0 322  MET A CB   1 ? 
ATOM   5045 C CB   B MET A 1 307 ? -15.419 -18.652 -16.931 0.250 9.508  0 322  MET A CB   1 ? 
ATOM   5046 C CB   C MET A 1 307 ? -15.363 -18.320 -17.004 0.500 10.633 0 322  MET A CB   1 ? 
ATOM   5047 C CG   A MET A 1 307 ? -14.237 -18.869 -17.416 0.250 5.735  0 322  MET A CG   1 ? 
ATOM   5048 C CG   B MET A 1 307 ? -14.425 -18.760 -18.052 0.250 10.167 0 322  MET A CG   1 ? 
ATOM   5049 C CG   C MET A 1 307 ? -14.812 -19.261 -16.018 0.500 11.723 0 322  MET A CG   1 ? 
ATOM   5050 S SD   A MET A 1 307 ? -13.820 -20.587 -17.061 0.250 5.282  0 322  MET A SD   1 ? 
ATOM   5051 S SD   B MET A 1 307 ? -12.742 -18.515 -17.473 0.250 11.449 0 322  MET A SD   1 ? 
ATOM   5052 S SD   C MET A 1 307 ? -13.042 -19.036 -15.734 0.500 13.077 0 322  MET A SD   1 ? 
ATOM   5053 C CE   A MET A 1 307 ? -12.255 -20.645 -17.940 0.250 5.748  0 322  MET A CE   1 ? 
ATOM   5054 C CE   B MET A 1 307 ? -13.122 -20.031 -16.573 0.250 11.149 0 322  MET A CE   1 ? 
ATOM   5055 C CE   C MET A 1 307 ? -13.252 -17.563 -14.728 0.500 14.014 0 322  MET A CE   1 ? 
ATOM   5056 H H    A MET A 1 307 ? -16.438 -17.375 -18.920 0.250 8.057  0 322  MET A H    1 c 
ATOM   5057 H H    B MET A 1 307 ? -16.491 -17.316 -18.821 0.250 9.034  0 322  MET A H    1 c 
ATOM   5058 H H    C MET A 1 307 ? -16.448 -17.352 -19.007 0.500 9.071  0 322  MET A H    1 c 
ATOM   5059 H HA   A MET A 1 307 ? -16.811 -19.700 -17.641 0.250 7.302  0 322  MET A HA   1 c 
ATOM   5060 H HA   B MET A 1 307 ? -17.010 -19.735 -17.693 0.250 9.011  0 322  MET A HA   1 c 
ATOM   5061 H HA   C MET A 1 307 ? -16.775 -19.653 -17.714 0.500 9.302  0 322  MET A HA   1 c 
ATOM   5062 H HB2  A MET A 1 307 ? -15.432 -17.408 -16.624 0.250 6.440  0 322  MET A HB2  1 c 
ATOM   5063 H HB2  B MET A 1 307 ? -15.317 -17.782 -16.489 0.250 9.538  0 322  MET A HB2  1 c 
ATOM   5064 H HB2  C MET A 1 307 ? -14.763 -18.282 -17.779 0.500 10.526 0 322  MET A HB2  1 c 
ATOM   5065 H HB3  A MET A 1 307 ? -15.503 -18.763 -15.810 0.250 6.440  0 322  MET A HB3  1 c 
ATOM   5066 H HB3  B MET A 1 307 ? -15.239 -19.353 -16.269 0.250 9.538  0 322  MET A HB3  1 c 
ATOM   5067 H HB3  C MET A 1 307 ? -15.395 -17.424 -16.606 0.500 10.526 0 322  MET A HB3  1 c 
ATOM   5068 H HG2  A MET A 1 307 ? -14.356 -18.772 -18.382 0.250 5.805  0 322  MET A HG2  1 c 
ATOM   5069 H HG2  B MET A 1 307 ? -14.493 -19.644 -18.465 0.250 10.230 0 322  MET A HG2  1 c 
ATOM   5070 H HG2  C MET A 1 307 ? -15.277 -19.138 -15.178 0.500 11.651 0 322  MET A HG2  1 c 
ATOM   5071 H HG3  A MET A 1 307 ? -13.482 -18.306 -17.152 0.250 5.805  0 322  MET A HG3  1 c 
ATOM   5072 H HG3  B MET A 1 307 ? -14.627 -18.092 -18.732 0.250 10.220 0 322  MET A HG3  1 c 
ATOM   5073 H HG3  C MET A 1 307 ? -14.970 -20.177 -16.321 0.500 11.676 0 322  MET A HG3  1 c 
ATOM   5074 H HE1  A MET A 1 307 ? -11.867 -21.536 -17.854 0.250 5.628  0 322  MET A HE1  1 c 
ATOM   5075 H HE1  B MET A 1 307 ? -12.394 -20.233 -15.957 0.250 11.221 0 322  MET A HE1  1 c 
ATOM   5076 H HE1  C MET A 1 307 ? -12.395 -17.311 -14.337 0.500 13.753 0 322  MET A HE1  1 c 
ATOM   5077 H HE2  A MET A 1 307 ? -12.404 -20.445 -18.882 0.250 5.628  0 322  MET A HE2  1 c 
ATOM   5078 H HE2  B MET A 1 307 ? -13.948 -19.912 -16.070 0.250 11.222 0 322  MET A HE2  1 c 
ATOM   5079 H HE2  C MET A 1 307 ? -13.580 -16.834 -15.287 0.500 13.752 0 322  MET A HE2  1 c 
ATOM   5080 H HE3  A MET A 1 307 ? -11.644 -19.987 -17.560 0.250 5.628  0 322  MET A HE3  1 c 
ATOM   5081 H HE3  B MET A 1 307 ? -13.228 -20.766 -17.205 0.250 11.222 0 322  MET A HE3  1 c 
ATOM   5082 H HE3  C MET A 1 307 ? -13.895 -17.739 -14.019 0.500 13.690 0 322  MET A HE3  1 c 
ATOM   5083 N N    . TYR A 1 308 ? -18.160 -17.180 -16.103 1.000 8.377  0 323  TYR A N    1 ? 
ATOM   5084 C CA   . TYR A 1 308 ? -19.165 -16.835 -15.098 1.000 8.040  0 323  TYR A CA   1 ? 
ATOM   5085 C C    . TYR A 1 308 ? -20.491 -17.556 -15.424 1.000 8.391  0 323  TYR A C    1 ? 
ATOM   5086 O O    . TYR A 1 308 ? -21.154 -18.130 -14.545 1.000 9.173  0 323  TYR A O    1 ? 
ATOM   5087 C CB   . TYR A 1 308 ? -19.403 -15.326 -15.014 1.000 8.376  0 323  TYR A CB   1 ? 
ATOM   5088 C CG   . TYR A 1 308 ? -18.475 -14.524 -14.116 1.000 8.537  0 323  TYR A CG   1 ? 
ATOM   5089 C CD1  . TYR A 1 308 ? -18.737 -14.409 -12.763 1.000 8.347  0 323  TYR A CD1  1 ? 
ATOM   5090 C CD2  . TYR A 1 308 ? -17.414 -13.796 -14.635 1.000 10.239 0 323  TYR A CD2  1 ? 
ATOM   5091 C CE1  . TYR A 1 308 ? -17.927 -13.649 -11.917 1.000 8.634  0 323  TYR A CE1  1 ? 
ATOM   5092 C CE2  . TYR A 1 308 ? -16.601 -13.068 -13.803 1.000 9.817  0 323  TYR A CE2  1 ? 
ATOM   5093 C CZ   . TYR A 1 308 ? -16.864 -12.977 -12.458 1.000 9.869  0 323  TYR A CZ   1 ? 
ATOM   5094 O OH   . TYR A 1 308 ? -16.003 -12.242 -11.676 1.000 11.151 0 323  TYR A OH   1 ? 
ATOM   5095 H H    . TYR A 1 308 ? -17.755 -16.514 -16.579 1.000 8.300  0 323  TYR A H    1 c 
ATOM   5096 H HA   . TYR A 1 308 ? -18.844 -17.151 -14.213 1.000 8.229  0 323  TYR A HA   1 c 
ATOM   5097 H HB2  . TYR A 1 308 ? -19.346 -14.958 -15.924 1.000 8.348  0 323  TYR A HB2  1 c 
ATOM   5098 H HB3  . TYR A 1 308 ? -20.326 -15.181 -14.708 1.000 8.357  0 323  TYR A HB3  1 c 
ATOM   5099 H HD1  . TYR A 1 308 ? -19.471 -14.875 -12.396 1.000 8.486  0 323  TYR A HD1  1 c 
ATOM   5100 H HD2  . TYR A 1 308 ? -17.215 -13.846 -15.554 1.000 9.679  0 323  TYR A HD2  1 c 
ATOM   5101 H HE1  . TYR A 1 308 ? -18.099 -13.609 -10.992 1.000 8.861  0 323  TYR A HE1  1 c 
ATOM   5102 H HE2  . TYR A 1 308 ? -15.866 -12.602 -14.163 1.000 9.906  0 323  TYR A HE2  1 c 
ATOM   5103 H HH   . TYR A 1 308 ? -15.356 -12.737 -11.407 0.000 11.150 0 323  TYR A HH   1 c 
ATOM   5104 N N    . LEU A 1 309 ? -20.924 -17.485 -16.687 1.000 8.013  0 324  LEU A N    1 ? 
ATOM   5105 C CA   . LEU A 1 309 ? -22.155 -18.126 -17.151 1.000 8.387  0 324  LEU A CA   1 ? 
ATOM   5106 C C    . LEU A 1 309 ? -22.090 -19.637 -16.962 1.000 8.819  0 324  LEU A C    1 ? 
ATOM   5107 O O    . LEU A 1 309 ? -23.034 -20.249 -16.421 1.000 9.461  0 324  LEU A O    1 ? 
ATOM   5108 C CB   . LEU A 1 309 ? -22.437 -17.783 -18.598 1.000 8.539  0 324  LEU A CB   1 ? 
ATOM   5109 C CG   . LEU A 1 309 ? -23.663 -18.460 -19.207 1.000 8.756  0 324  LEU A CG   1 ? 
ATOM   5110 C CD1  . LEU A 1 309 ? -24.958 -18.078 -18.472 1.000 9.020  0 324  LEU A CD1  1 ? 
ATOM   5111 C CD2  . LEU A 1 309 ? -23.756 -18.167 -20.692 1.000 10.334 0 324  LEU A CD2  1 ? 
ATOM   5112 H H    . LEU A 1 309 ? -20.432 -17.008 -17.292 1.000 8.188  0 324  LEU A H    1 c 
ATOM   5113 H HA   . LEU A 1 309 ? -22.898 -17.783 -16.594 1.000 8.427  0 324  LEU A HA   1 c 
ATOM   5114 H HB2  . LEU A 1 309 ? -22.554 -16.807 -18.665 1.000 8.552  0 324  LEU A HB2  1 c 
ATOM   5115 H HB3  . LEU A 1 309 ? -21.647 -18.030 -19.132 1.000 8.552  0 324  LEU A HB3  1 c 
ATOM   5116 H HG   . LEU A 1 309 ? -23.548 -19.440 -19.111 1.000 9.041  0 324  LEU A HG   1 c 
ATOM   5117 H HD11 . LEU A 1 309 ? -24.942 -18.443 -17.572 1.000 8.936  0 324  LEU A HD11 1 c 
ATOM   5118 H HD12 . LEU A 1 309 ? -25.722 -18.437 -18.953 1.000 8.940  0 324  LEU A HD12 1 c 
ATOM   5119 H HD13 . LEU A 1 309 ? -25.032 -17.109 -18.427 1.000 8.940  0 324  LEU A HD13 1 c 
ATOM   5120 H HD21 . LEU A 1 309 ? -22.960 -18.500 -21.139 1.000 9.839  0 324  LEU A HD21 1 c 
ATOM   5121 H HD22 . LEU A 1 309 ? -23.827 -17.207 -20.830 1.000 9.839  0 324  LEU A HD22 1 c 
ATOM   5122 H HD23 . LEU A 1 309 ? -24.541 -18.605 -21.061 1.000 9.839  0 324  LEU A HD23 1 c 
ATOM   5123 N N    . ALA A 1 310 ? -20.978 -20.242 -17.391 1.000 8.528  0 325  ALA A N    1 ? 
ATOM   5124 C CA   . ALA A 1 310 ? -20.846 -21.690 -17.278 1.000 9.605  0 325  ALA A CA   1 ? 
ATOM   5125 C C    . ALA A 1 310 ? -20.918 -22.118 -15.825 1.000 9.660  0 325  ALA A C    1 ? 
ATOM   5126 O O    . ALA A 1 310 ? -21.485 -23.162 -15.484 1.000 10.197 0 325  ALA A O    1 ? 
ATOM   5127 C CB   . ALA A 1 310 ? -19.543 -22.152 -17.927 1.000 8.691  0 325  ALA A CB   1 ? 
ATOM   5128 H H    . ALA A 1 310 ? -20.299 -19.756 -17.762 1.000 8.819  0 325  ALA A H    1 c 
ATOM   5129 H HA   . ALA A 1 310 ? -21.612 -22.108 -17.760 1.000 9.226  0 325  ALA A HA   1 c 
ATOM   5130 H HB1  . ALA A 1 310 ? -19.491 -21.811 -18.836 1.000 8.956  0 325  ALA A HB1  1 c 
ATOM   5131 H HB2  . ALA A 1 310 ? -18.786 -21.820 -17.416 1.000 8.955  0 325  ALA A HB2  1 c 
ATOM   5132 H HB3  . ALA A 1 310 ? -19.515 -23.123 -17.947 1.000 8.969  0 325  ALA A HB3  1 c 
ATOM   5133 N N    . GLY A 1 311 ? -20.287 -21.371 -14.918 1.000 9.117  0 326  GLY A N    1 ? 
ATOM   5134 C CA   . GLY A 1 311 ? -20.291 -21.717 -13.513 1.000 9.272  0 326  GLY A CA   1 ? 
ATOM   5135 C C    . GLY A 1 311 ? -21.699 -21.727 -12.928 1.000 10.798 0 326  GLY A C    1 ? 
ATOM   5136 O O    . GLY A 1 311 ? -22.064 -22.643 -12.186 1.000 11.988 0 326  GLY A O    1 ? 
ATOM   5137 H H    . GLY A 1 311 ? -19.834 -20.623 -15.185 1.000 9.275  0 326  GLY A H    1 c 
ATOM   5138 H HA2  . GLY A 1 311 ? -19.882 -22.608 -13.401 1.000 9.557  0 326  GLY A HA2  1 c 
ATOM   5139 H HA3  . GLY A 1 311 ? -19.736 -21.067 -13.021 1.000 9.554  0 326  GLY A HA3  1 c 
ATOM   5140 N N    . TYR A 1 312 ? -22.498 -20.747 -13.288 1.000 9.832  0 327  TYR A N    1 ? 
ATOM   5141 C CA   . TYR A 1 312 ? -23.906 -20.731 -12.871 1.000 11.190 0 327  TYR A CA   1 ? 
ATOM   5142 C C    . TYR A 1 312 ? -24.625 -21.992 -13.356 1.000 10.718 0 327  TYR A C    1 ? 
ATOM   5143 O O    . TYR A 1 312 ? -25.262 -22.667 -12.548 1.000 11.259 0 327  TYR A O    1 ? 
ATOM   5144 C CB   . TYR A 1 312 ? -24.589 -19.483 -13.413 1.000 11.741 0 327  TYR A CB   1 ? 
ATOM   5145 C CG   . TYR A 1 312 ? -26.076 -19.430 -13.136 1.000 13.017 0 327  TYR A CG   1 ? 
ATOM   5146 C CD1  . TYR A 1 312 ? -26.543 -18.959 -11.923 1.000 14.054 0 327  TYR A CD1  1 ? 
ATOM   5147 C CD2  . TYR A 1 312 ? -26.973 -19.812 -14.126 1.000 15.641 0 327  TYR A CD2  1 ? 
ATOM   5148 C CE1  . TYR A 1 312 ? -27.910 -18.910 -11.680 1.000 16.969 0 327  TYR A CE1  1 ? 
ATOM   5149 C CE2  . TYR A 1 312 ? -28.339 -19.759 -13.890 1.000 18.760 0 327  TYR A CE2  1 ? 
ATOM   5150 C CZ   . TYR A 1 312 ? -28.779 -19.273 -12.678 1.000 17.880 0 327  TYR A CZ   1 ? 
ATOM   5151 O OH   . TYR A 1 312 ? -30.139 -19.193 -12.398 1.000 24.251 0 327  TYR A OH   1 ? 
ATOM   5152 H H    . TYR A 1 312 ? -22.177 -20.061 -13.799 1.000 10.342 0 327  TYR A H    1 c 
ATOM   5153 H HA   . TYR A 1 312 ? -23.941 -20.706 -11.878 1.000 10.946 0 327  TYR A HA   1 c 
ATOM   5154 H HB2  . TYR A 1 312 ? -24.162 -18.696 -13.011 1.000 11.877 0 327  TYR A HB2  1 c 
ATOM   5155 H HB3  . TYR A 1 312 ? -24.444 -19.444 -14.384 1.000 11.912 0 327  TYR A HB3  1 c 
ATOM   5156 H HD1  . TYR A 1 312 ? -25.934 -18.694 -11.252 1.000 14.496 0 327  TYR A HD1  1 c 
ATOM   5157 H HD2  . TYR A 1 312 ? -26.653 -20.125 -14.957 1.000 15.613 0 327  TYR A HD2  1 c 
ATOM   5158 H HE1  . TYR A 1 312 ? -28.238 -18.583 -10.860 1.000 16.522 0 327  TYR A HE1  1 c 
ATOM   5159 H HE2  . TYR A 1 312 ? -28.953 -20.010 -14.558 1.000 17.741 0 327  TYR A HE2  1 c 
ATOM   5160 H HH   . TYR A 1 312 ? -30.435 -18.416 -12.606 0.000 24.260 0 327  TYR A HH   1 c 
ATOM   5161 N N    . HIS A 1 313 ? -24.466 -22.341 -14.631 1.000 10.171 0 328  HIS A N    1 ? 
ATOM   5162 C CA   . HIS A 1 313 ? -25.111 -23.547 -15.155 1.000 11.034 0 328  HIS A CA   1 ? 
ATOM   5163 C C    . HIS A 1 313 ? -24.579 -24.805 -14.483 1.000 11.928 0 328  HIS A C    1 ? 
ATOM   5164 O O    . HIS A 1 313 ? -25.371 -25.729 -14.194 1.000 13.735 0 328  HIS A O    1 ? 
ATOM   5165 C CB   . HIS A 1 313 ? -24.986 -23.593 -16.660 1.000 11.263 0 328  HIS A CB   1 ? 
ATOM   5166 C CG   . HIS A 1 313 ? -25.864 -22.596 -17.344 1.000 10.900 0 328  HIS A CG   1 ? 
ATOM   5167 N ND1  . HIS A 1 313 ? -27.239 -22.560 -17.104 1.000 12.264 0 328  HIS A ND1  1 ? 
ATOM   5168 C CD2  . HIS A 1 313 ? -25.665 -21.678 -18.277 1.000 12.128 0 328  HIS A CD2  1 ? 
ATOM   5169 C CE1  . HIS A 1 313 ? -27.759 -21.630 -17.890 1.000 12.279 0 328  HIS A CE1  1 ? 
ATOM   5170 N NE2  . HIS A 1 313 ? -26.847 -21.069 -18.627 1.000 12.153 0 328  HIS A NE2  1 ? 
ATOM   5171 H H    . HIS A 1 313 ? -23.956 -21.826 -15.188 1.000 10.498 0 328  HIS A H    1 c 
ATOM   5172 H HA   . HIS A 1 313 ? -26.073 -23.475 -14.936 1.000 11.065 0 328  HIS A HA   1 c 
ATOM   5173 H HB2  . HIS A 1 313 ? -24.052 -23.421 -16.907 1.000 11.122 0 328  HIS A HB2  1 c 
ATOM   5174 H HB3  . HIS A 1 313 ? -25.224 -24.494 -16.971 1.000 11.129 0 328  HIS A HB3  1 c 
ATOM   5175 H HD1  . HIS A 1 313 ? -27.675 -23.096 -16.558 0.000 12.260 0 328  HIS A HD1  1 c 
ATOM   5176 H HD2  . HIS A 1 313 ? -24.835 -21.474 -18.662 1.000 11.834 0 328  HIS A HD2  1 c 
ATOM   5177 H HE1  . HIS A 1 313 ? -28.674 -21.405 -17.894 1.000 12.236 0 328  HIS A HE1  1 c 
ATOM   5178 H HE2  . HIS A 1 313 ? -26.988 -20.431 -19.211 0.000 12.150 0 328  HIS A HE2  1 c 
ATOM   5179 N N    A CYS A 1 314 ? -23.270 -24.851 -14.170 0.250 11.822 0 329  CYS A N    1 ? 
ATOM   5180 N N    B CYS A 1 314 ? -23.260 -24.884 -14.268 0.250 12.479 0 329  CYS A N    1 ? 
ATOM   5181 N N    C CYS A 1 314 ? -23.315 -24.822 -14.102 0.500 11.659 0 329  CYS A N    1 ? 
ATOM   5182 C CA   A CYS A 1 314 ? -22.634 -25.978 -13.483 0.250 12.161 0 329  CYS A CA   1 ? 
ATOM   5183 C CA   B CYS A 1 314 ? -22.710 -25.968 -13.468 0.250 13.241 0 329  CYS A CA   1 ? 
ATOM   5184 C CA   C CYS A 1 314 ? -22.752 -26.017 -13.518 0.500 12.544 0 329  CYS A CA   1 ? 
ATOM   5185 C C    A CYS A 1 314 ? -23.260 -26.185 -12.100 0.250 12.681 0 329  CYS A C    1 ? 
ATOM   5186 C C    B CYS A 1 314 ? -23.520 -26.106 -12.198 0.250 13.122 0 329  CYS A C    1 ? 
ATOM   5187 C C    C CYS A 1 314 ? -23.233 -26.199 -12.062 0.500 12.505 0 329  CYS A C    1 ? 
ATOM   5188 O O    A CYS A 1 314 ? -23.642 -27.313 -11.739 0.250 13.268 0 329  CYS A O    1 ? 
ATOM   5189 O O    B CYS A 1 314 ? -24.269 -27.078 -12.057 0.250 13.119 0 329  CYS A O    1 ? 
ATOM   5190 O O    C CYS A 1 314 ? -23.536 -27.324 -11.574 0.500 12.099 0 329  CYS A O    1 ? 
ATOM   5191 C CB   A CYS A 1 314 ? -21.112 -25.787 -13.437 0.250 11.439 0 329  CYS A CB   1 ? 
ATOM   5192 C CB   B CYS A 1 314 ? -21.306 -25.727 -12.937 0.250 13.420 0 329  CYS A CB   1 ? 
ATOM   5193 C CB   C CYS A 1 314 ? -21.260 -25.953 -13.805 0.500 12.050 0 329  CYS A CB   1 ? 
ATOM   5194 S SG   A CYS A 1 314 ? -20.154 -27.099 -12.621 0.250 9.703  0 329  CYS A SG   1 ? 
ATOM   5195 S SG   B CYS A 1 314 ? -20.042 -26.070 -14.173 0.250 13.378 0 329  CYS A SG   1 ? 
ATOM   5196 S SG   C CYS A 1 314 ? -20.480 -27.410 -13.120 0.500 11.861 0 329  CYS A SG   1 ? 
ATOM   5197 H H    A CYS A 1 314 ? -22.744 -24.142 -14.404 0.250 11.904 0 329  CYS A H    1 c 
ATOM   5198 H H    B CYS A 1 314 ? -22.696 -24.260 -14.625 0.250 12.484 0 329  CYS A H    1 c 
ATOM   5199 H H    C CYS A 1 314 ? -22.786 -24.085 -14.214 0.500 11.886 0 329  CYS A H    1 c 
ATOM   5200 H HA   A CYS A 1 314 ? -22.811 -26.791 -14.021 0.250 12.051 0 329  CYS A HA   1 c 
ATOM   5201 H HA   B CYS A 1 314 ? -22.763 -26.811 -13.986 0.250 13.099 0 329  CYS A HA   1 c 
ATOM   5202 H HA   C CYS A 1 314 ? -23.091 -26.788 -14.041 0.500 12.273 0 329  CYS A HA   1 c 
ATOM   5203 H HB2  A CYS A 1 314 ? -20.782 -25.701 -14.359 0.250 11.259 0 329  CYS A HB2  1 c 
ATOM   5204 H HB2  B CYS A 1 314 ? -21.218 -24.791 -12.656 0.250 13.404 0 329  CYS A HB2  1 c 
ATOM   5205 H HB2  C CYS A 1 314 ? -21.103 -25.922 -14.775 0.500 12.128 0 329  CYS A HB2  1 c 
ATOM   5206 H HB3  A CYS A 1 314 ? -20.919 -24.941 -12.976 0.250 11.296 0 329  CYS A HB3  1 c 
ATOM   5207 H HB3  B CYS A 1 314 ? -21.148 -26.302 -12.156 0.250 13.410 0 329  CYS A HB3  1 c 
ATOM   5208 H HB3  C CYS A 1 314 ? -20.871 -25.149 -13.393 0.500 12.128 0 329  CYS A HB3  1 c 
ATOM   5209 H HG   A CYS A 1 314 ? -19.054 -26.617 -12.787 0.000 9.690  0 329  CYS A HG   1 c 
ATOM   5210 H HG   B CYS A 1 314 ? -19.076 -25.799 -13.493 0.000 13.380 0 329  CYS A HG   1 c 
ATOM   5211 H HG   C CYS A 1 314 ? -19.343 -27.153 -13.453 0.000 11.870 0 329  CYS A HG   1 c 
ATOM   5212 N N    . ARG A 1 315 ? -23.379 -25.094 -11.327 1.000 13.428 0 330  ARG A N    1 ? 
ATOM   5213 C CA   . ARG A 1 315 ? -23.966 -25.111 -9.995  1.000 14.342 0 330  ARG A CA   1 ? 
ATOM   5214 C C    . ARG A 1 315 ? -25.415 -25.600 -10.025 1.000 16.174 0 330  ARG A C    1 ? 
ATOM   5215 O O    . ARG A 1 315 ? -25.858 -26.275 -9.083  1.000 17.294 0 330  ARG A O    1 ? 
ATOM   5216 C CB   . ARG A 1 315 ? -23.879 -23.719 -9.334  1.000 15.054 0 330  ARG A CB   1 ? 
ATOM   5217 C CG   . ARG A 1 315 ? -22.452 -23.351 -8.946  1.000 15.202 0 330  ARG A CG   1 ? 
ATOM   5218 C CD   . ARG A 1 315 ? -22.390 -22.043 -8.115  1.000 13.798 0 330  ARG A CD   1 ? 
ATOM   5219 N NE   . ARG A 1 315 ? -22.856 -20.866 -8.823  1.000 15.545 0 330  ARG A NE   1 ? 
ATOM   5220 C CZ   . ARG A 1 315 ? -22.098 -20.115 -9.625  1.000 14.486 0 330  ARG A CZ   1 ? 
ATOM   5221 N NH1  . ARG A 1 315 ? -20.875 -20.528 -9.907  1.000 18.026 0 330  ARG A NH1  1 ? 
ATOM   5222 N NH2  . ARG A 1 315 ? -22.609 -19.049 -10.142 1.000 14.454 0 330  ARG A NH2  1 ? 
ATOM   5223 H H    . ARG A 1 315 ? -23.027 -24.306 -11.624 1.000 13.223 0 330  ARG A H    1 c 
ATOM   5224 H HA   . ARG A 1 315 ? -23.441 -25.743 -9.440  1.000 14.590 0 330  ARG A HA   1 c 
ATOM   5225 H HB2  . ARG A 1 315 ? -24.225 -23.045 -9.957  1.000 14.926 0 330  ARG A HB2  1 c 
ATOM   5226 H HB3  . ARG A 1 315 ? -24.442 -23.707 -8.531  1.000 14.931 0 330  ARG A HB3  1 c 
ATOM   5227 H HG2  . ARG A 1 315 ? -22.061 -24.082 -8.419  1.000 14.840 0 330  ARG A HG2  1 c 
ATOM   5228 H HG3  . ARG A 1 315 ? -21.912 -23.242 -9.757  1.000 14.837 0 330  ARG A HG3  1 c 
ATOM   5229 H HD2  . ARG A 1 315 ? -22.933 -22.163 -7.310  1.000 14.509 0 330  ARG A HD2  1 c 
ATOM   5230 H HD3  . ARG A 1 315 ? -21.466 -21.898 -7.826  1.000 14.523 0 330  ARG A HD3  1 c 
ATOM   5231 H HE   . ARG A 1 315 ? -23.689 -20.637 -8.720  1.000 14.883 0 330  ARG A HE   1 c 
ATOM   5232 H HH11 . ARG A 1 315 ? -20.186 -19.998 -9.740  1.000 16.832 0 330  ARG A HH11 1 c 
ATOM   5233 H HH12 . ARG A 1 315 ? -20.748 -21.327 -10.263 1.000 16.771 0 330  ARG A HH12 1 c 
ATOM   5234 H HH21 . ARG A 1 315 ? -22.125 -18.557 -10.694 1.000 14.490 0 330  ARG A HH21 1 c 
ATOM   5235 H HH22 . ARG A 1 315 ? -23.437 -18.810 -9.945  1.000 14.481 0 330  ARG A HH22 1 c 
ATOM   5236 N N    . ASN A 1 316 ? -26.152 -25.282 -11.072 1.000 13.639 0 331  ASN A N    1 ? 
ATOM   5237 C CA   . ASN A 1 316 ? -27.563 -25.620 -11.203 1.000 16.608 0 331  ASN A CA   1 ? 
ATOM   5238 C C    . ASN A 1 316 ? -27.691 -26.972 -11.926 1.000 16.337 0 331  ASN A C    1 ? 
ATOM   5239 O O    . ASN A 1 316 ? -28.817 -27.348 -12.256 1.000 19.720 0 331  ASN A O    1 ? 
ATOM   5240 C CB   . ASN A 1 316 ? -28.291 -24.457 -11.845 1.000 17.929 0 331  ASN A CB   1 ? 
ATOM   5241 C CG   . ASN A 1 316 ? -28.373 -23.279 -10.889 1.000 21.164 0 331  ASN A CG   1 ? 
ATOM   5242 O OD1  . ASN A 1 316 ? -29.142 -23.333 -9.920  1.000 25.167 0 331  ASN A OD1  1 ? 
ATOM   5243 N ND2  . ASN A 1 316 ? -27.577 -22.221 -11.026 1.000 23.547 0 331  ASN A ND2  1 ? 
ATOM   5244 H H    . ASN A 1 316 ? -25.765 -24.801 -11.746 1.000 14.845 0 331  ASN A H    1 c 
ATOM   5245 H HA   . ASN A 1 316 ? -27.935 -25.728 -10.298 1.000 16.231 0 331  ASN A HA   1 c 
ATOM   5246 H HB2  . ASN A 1 316 ? -27.820 -24.186 -12.658 1.000 18.298 0 331  ASN A HB2  1 c 
ATOM   5247 H HB3  . ASN A 1 316 ? -29.195 -24.736 -12.094 1.000 18.305 0 331  ASN A HB3  1 c 
ATOM   5248 H HD21 . ASN A 1 316 ? -26.993 -22.191 -11.692 1.000 22.649 0 331  ASN A HD21 1 c 
ATOM   5249 H HD22 . ASN A 1 316 ? -27.631 -21.547 -10.451 1.000 22.771 0 331  ASN A HD22 1 c 
ATOM   5250 N N    . ARG A 1 317 ? -26.549 -27.655 -12.181 1.000 17.110 0 332  ARG A N    1 ? 
ATOM   5251 C CA   . ARG A 1 317 ? -26.448 -28.975 -12.805 1.000 18.260 0 332  ARG A CA   1 ? 
ATOM   5252 C C    . ARG A 1 317 ? -27.123 -28.956 -14.163 1.000 19.917 0 332  ARG A C    1 ? 
ATOM   5253 O O    . ARG A 1 317 ? -27.585 -30.009 -14.626 1.000 22.340 0 332  ARG A O    1 ? 
ATOM   5254 C CB   . ARG A 1 317 ? -26.988 -30.088 -11.895 1.000 19.864 0 332  ARG A CB   1 ? 
ATOM   5255 C CG   . ARG A 1 317 ? -26.241 -30.207 -10.580 1.000 25.521 0 332  ARG A CG   1 ? 
ATOM   5256 C CD   . ARG A 1 317 ? -24.917 -30.802 -10.949 1.000 32.314 0 332  ARG A CD   1 ? 
ATOM   5257 N NE   . ARG A 1 317 ? -23.979 -30.863 -9.840  1.000 38.137 0 332  ARG A NE   1 ? 
ATOM   5258 C CZ   . ARG A 1 317 ? -22.853 -31.582 -9.859  1.000 45.779 0 332  ARG A CZ   1 ? 
ATOM   5259 N NH1  . ARG A 1 317 ? -21.926 -31.345 -8.945  1.000 52.337 0 332  ARG A NH1  1 ? 
ATOM   5260 N NH2  . ARG A 1 317 ? -22.637 -32.510 -10.791 1.000 37.393 0 332  ARG A NH2  1 ? 
ATOM   5261 H H    . ARG A 1 317 ? -25.767 -27.259 -11.933 1.000 16.994 0 332  ARG A H    1 c 
ATOM   5262 H HA   . ARG A 1 317 ? -25.489 -29.156 -12.962 1.000 18.718 0 332  ARG A HA   1 c 
ATOM   5263 H HB2  . ARG A 1 317 ? -27.934 -29.910 -11.706 1.000 20.674 0 332  ARG A HB2  1 c 
ATOM   5264 H HB3  . ARG A 1 317 ? -26.934 -30.944 -12.370 1.000 20.778 0 332  ARG A HB3  1 c 
ATOM   5265 H HG2  . ARG A 1 317 ? -26.112 -29.323 -10.173 1.000 25.414 0 332  ARG A HG2  1 c 
ATOM   5266 H HG3  . ARG A 1 317 ? -26.720 -30.804 -9.964  1.000 25.456 0 332  ARG A HG3  1 c 
ATOM   5267 H HD2  . ARG A 1 317 ? -25.069 -31.702 -11.293 1.000 31.498 0 332  ARG A HD2  1 c 
ATOM   5268 H HD3  . ARG A 1 317 ? -24.514 -30.278 -11.667 1.000 31.451 0 332  ARG A HD3  1 c 
ATOM   5269 H HE   . ARG A 1 317 ? -24.162 -30.407 -9.121  1.000 38.382 0 332  ARG A HE   1 c 
ATOM   5270 H HH11 . ARG A 1 317 ? -21.214 -31.867 -8.897  1.000 50.059 0 332  ARG A HH11 1 c 
ATOM   5271 H HH12 . ARG A 1 317 ? -22.018 -30.667 -8.385  1.000 49.975 0 332  ARG A HH12 1 c 
ATOM   5272 H HH21 . ARG A 1 317 ? -21.824 -32.607 -11.125 1.000 38.688 0 332  ARG A HH21 1 c 
ATOM   5273 H HH22 . ARG A 1 317 ? -23.296 -33.032 -11.063 1.000 39.140 0 332  ARG A HH22 1 c 
ATOM   5274 N N    . ASN A 1 318 ? -27.104 -27.810 -14.835 1.000 17.091 0 333  ASN A N    1 ? 
ATOM   5275 C CA   . ASN A 1 318 ? -27.608 -27.676 -16.168 1.000 16.489 0 333  ASN A CA   1 ? 
ATOM   5276 C C    . ASN A 1 318 ? -26.516 -27.992 -17.190 1.000 16.795 0 333  ASN A C    1 ? 
ATOM   5277 O O    . ASN A 1 318 ? -25.835 -27.092 -17.708 1.000 17.100 0 333  ASN A O    1 ? 
ATOM   5278 C CB   . ASN A 1 318 ? -28.081 -26.280 -16.427 1.000 18.312 0 333  ASN A CB   1 ? 
ATOM   5279 C CG   . ASN A 1 318 ? -28.896 -26.209 -17.674 1.000 20.535 0 333  ASN A CG   1 ? 
ATOM   5280 O OD1  . ASN A 1 318 ? -28.751 -27.041 -18.602 1.000 21.671 0 333  ASN A OD1  1 ? 
ATOM   5281 N ND2  . ASN A 1 318 ? -29.861 -25.314 -17.648 1.000 21.743 0 333  ASN A ND2  1 ? 
ATOM   5282 H H    . ASN A 1 318 ? -26.735 -27.073 -14.440 1.000 17.575 0 333  ASN A H    1 c 
ATOM   5283 H HA   . ASN A 1 318 ? -28.369 -28.288 -16.291 1.000 17.059 0 333  ASN A HA   1 c 
ATOM   5284 H HB2  . ASN A 1 318 ? -28.623 -25.982 -15.670 1.000 18.408 0 333  ASN A HB2  1 c 
ATOM   5285 H HB3  . ASN A 1 318 ? -27.313 -25.680 -16.505 1.000 18.349 0 333  ASN A HB3  1 c 
ATOM   5286 H HD21 . ASN A 1 318 ? -29.866 -24.676 -17.031 1.000 21.312 0 333  ASN A HD21 1 c 
ATOM   5287 H HD22 . ASN A 1 318 ? -30.508 -25.349 -18.255 1.000 21.354 0 333  ASN A HD22 1 c 
ATOM   5288 N N    . VAL A 1 319 ? -26.341 -29.279 -17.462 1.000 15.448 0 334  VAL A N    1 ? 
ATOM   5289 C CA   . VAL A 1 319 ? -25.191 -29.755 -18.228 1.000 14.265 0 334  VAL A CA   1 ? 
ATOM   5290 C C    . VAL A 1 319 ? -25.170 -29.163 -19.630 1.000 13.149 0 334  VAL A C    1 ? 
ATOM   5291 O O    . VAL A 1 319 ? -24.102 -28.763 -20.122 1.000 12.038 0 334  VAL A O    1 ? 
ATOM   5292 C CB   . VAL A 1 319 ? -25.178 -31.300 -18.286 1.000 15.130 0 334  VAL A CB   1 ? 
ATOM   5293 C CG1  . VAL A 1 319 ? -24.005 -31.862 -19.041 1.000 15.981 0 334  VAL A CG1  1 ? 
ATOM   5294 C CG2  . VAL A 1 319 ? -25.244 -31.868 -16.865 1.000 17.576 0 334  VAL A CG2  1 ? 
ATOM   5295 H H    . VAL A 1 319 ? -26.964 -29.884 -17.178 1.000 15.519 0 334  VAL A H    1 c 
ATOM   5296 H HA   . VAL A 1 319 ? -24.384 -29.463 -17.765 1.000 14.414 0 334  VAL A HA   1 c 
ATOM   5297 H HB   . VAL A 1 319 ? -25.998 -31.579 -18.757 1.000 15.549 0 334  VAL A HB   1 c 
ATOM   5298 H HG11 . VAL A 1 319 ? -23.181 -31.487 -18.687 1.000 15.721 0 334  VAL A HG11 1 c 
ATOM   5299 H HG12 . VAL A 1 319 ? -24.084 -31.636 -19.983 1.000 15.710 0 334  VAL A HG12 1 c 
ATOM   5300 H HG13 . VAL A 1 319 ? -23.988 -32.829 -18.944 1.000 15.727 0 334  VAL A HG13 1 c 
ATOM   5301 H HG21 . VAL A 1 319 ? -24.898 -32.777 -16.859 1.000 16.763 0 334  VAL A HG21 1 c 
ATOM   5302 H HG22 . VAL A 1 319 ? -26.167 -31.874 -16.560 1.000 16.759 0 334  VAL A HG22 1 c 
ATOM   5303 H HG23 . VAL A 1 319 ? -24.712 -31.315 -16.272 1.000 16.646 0 334  VAL A HG23 1 c 
ATOM   5304 N N    A ARG A 1 320 ? -26.314 -29.176 -20.268 0.500 11.711 0 335  ARG A N    1 ? 
ATOM   5305 N N    B ARG A 1 320 ? -26.306 -29.107 -20.353 0.500 12.362 0 335  ARG A N    1 ? 
ATOM   5306 C CA   A ARG A 1 320 ? -26.418 -28.676 -21.603 0.500 10.216 0 335  ARG A CA   1 ? 
ATOM   5307 C CA   B ARG A 1 320 ? -26.315 -28.627 -21.729 0.500 11.876 0 335  ARG A CA   1 ? 
ATOM   5308 C C    A ARG A 1 320 ? -25.841 -27.252 -21.745 0.500 11.082 0 335  ARG A C    1 ? 
ATOM   5309 C C    B ARG A 1 320 ? -25.839 -27.172 -21.835 0.500 11.465 0 335  ARG A C    1 ? 
ATOM   5310 O O    A ARG A 1 320 ? -24.957 -26.979 -22.547 0.500 10.915 0 335  ARG A O    1 ? 
ATOM   5311 O O    B ARG A 1 320 ? -25.084 -26.799 -22.745 0.500 10.655 0 335  ARG A O    1 ? 
ATOM   5312 C CB   A ARG A 1 320 ? -27.922 -28.862 -21.791 0.500 10.944 0 335  ARG A CB   1 ? 
ATOM   5313 C CB   B ARG A 1 320 ? -27.692 -28.718 -22.405 0.500 13.500 0 335  ARG A CB   1 ? 
ATOM   5314 C CG   A ARG A 1 320 ? -28.255 -28.190 -23.105 0.500 9.847  0 335  ARG A CG   1 ? 
ATOM   5315 C CG   B ARG A 1 320 ? -27.872 -28.132 -23.785 0.500 15.312 0 335  ARG A CG   1 ? 
ATOM   5316 C CD   A ARG A 1 320 ? -29.737 -28.335 -23.467 0.500 11.765 0 335  ARG A CD   1 ? 
ATOM   5317 C CD   B ARG A 1 320 ? -29.361 -28.305 -24.155 0.500 17.788 0 335  ARG A CD   1 ? 
ATOM   5318 N NE   A ARG A 1 320 ? -29.957 -29.742 -23.799 0.500 11.202 0 335  ARG A NE   1 ? 
ATOM   5319 N NE   B ARG A 1 320 ? -29.361 -27.425 -25.299 0.500 20.419 0 335  ARG A NE   1 ? 
ATOM   5320 C CZ   A ARG A 1 320 ? -30.463 -30.639 -22.973 0.500 12.355 0 335  ARG A CZ   1 ? 
ATOM   5321 C CZ   B ARG A 1 320 ? -28.836 -27.806 -26.433 0.500 19.790 0 335  ARG A CZ   1 ? 
ATOM   5322 N NH1  A ARG A 1 320 ? -30.634 -31.853 -23.409 0.500 11.959 0 335  ARG A NH1  1 ? 
ATOM   5323 N NH1  B ARG A 1 320 ? -29.475 -28.730 -27.174 0.500 15.700 0 335  ARG A NH1  1 ? 
ATOM   5324 N NH2  A ARG A 1 320 ? -30.838 -30.296 -21.744 0.500 11.239 0 335  ARG A NH2  1 ? 
ATOM   5325 N NH2  B ARG A 1 320 ? -27.793 -27.089 -26.829 0.500 15.974 0 335  ARG A NH2  1 ? 
ATOM   5326 H H    A ARG A 1 320 ? -27.060 -29.514 -19.862 0.500 11.705 0 335  ARG A H    1 c 
ATOM   5327 H H    B ARG A 1 320 ? -27.094 -29.377 -19.976 0.500 12.450 0 335  ARG A H    1 c 
ATOM   5328 H HA   A ARG A 1 320 ? -25.927 -29.286 -22.208 0.500 10.796 0 335  ARG A HA   1 c 
ATOM   5329 H HA   B ARG A 1 320 ? -25.687 -29.191 -22.248 0.500 12.182 0 335  ARG A HA   1 c 
ATOM   5330 H HB2  A ARG A 1 320 ? -28.153 -29.814 -21.830 0.500 10.528 0 335  ARG A HB2  1 c 
ATOM   5331 H HB2  B ARG A 1 320 ? -27.938 -29.667 -22.446 0.500 13.503 0 335  ARG A HB2  1 c 
ATOM   5332 H HB3  A ARG A 1 320 ? -28.417 -28.438 -21.059 0.500 10.559 0 335  ARG A HB3  1 c 
ATOM   5333 H HB3  B ARG A 1 320 ? -28.339 -28.283 -21.809 0.500 13.501 0 335  ARG A HB3  1 c 
ATOM   5334 H HG2  A ARG A 1 320 ? -28.031 -27.235 -23.046 0.500 10.504 0 335  ARG A HG2  1 c 
ATOM   5335 H HG2  B ARG A 1 320 ? -27.639 -27.178 -23.781 0.500 15.383 0 335  ARG A HG2  1 c 
ATOM   5336 H HG3  A ARG A 1 320 ? -27.710 -28.586 -23.819 0.500 10.515 0 335  ARG A HG3  1 c 
ATOM   5337 H HG3  B ARG A 1 320 ? -27.310 -28.607 -24.434 0.500 15.378 0 335  ARG A HG3  1 c 
ATOM   5338 H HD2  A ARG A 1 320 ? -30.306 -28.080 -22.713 0.500 11.219 0 335  ARG A HD2  1 c 
ATOM   5339 H HD2  B ARG A 1 320 ? -29.589 -29.219 -24.421 0.500 17.806 0 335  ARG A HD2  1 c 
ATOM   5340 H HD3  A ARG A 1 320 ? -29.961 -27.774 -24.238 0.500 11.188 0 335  ARG A HD3  1 c 
ATOM   5341 H HD3  B ARG A 1 320 ? -29.971 -27.976 -23.464 0.500 17.806 0 335  ARG A HD3  1 c 
ATOM   5342 H HE   A ARG A 1 320 ? -29.739 -30.011 -24.599 0.500 11.596 0 335  ARG A HE   1 c 
ATOM   5343 H HE   B ARG A 1 320 ? -29.715 -26.632 -25.232 0.500 19.631 0 335  ARG A HE   1 c 
ATOM   5344 H HH11 A ARG A 1 320 ? -30.886 -32.489 -22.849 0.500 12.078 0 335  ARG A HH11 1 c 
ATOM   5345 H HH11 B ARG A 1 320 ? -29.360 -28.746 -28.049 0.500 16.927 0 335  ARG A HH11 1 c 
ATOM   5346 H HH12 A ARG A 1 320 ? -30.497 -32.035 -24.263 0.500 12.075 0 335  ARG A HH12 1 c 
ATOM   5347 H HH12 B ARG A 1 320 ? -30.009 -29.316 -26.781 0.500 16.877 0 335  ARG A HH12 1 c 
ATOM   5348 H HH21 A ARG A 1 320 ? -31.175 -30.907 -21.201 0.500 11.571 0 335  ARG A HH21 1 c 
ATOM   5349 H HH21 B ARG A 1 320 ? -27.387 -27.288 -27.588 0.500 17.065 0 335  ARG A HH21 1 c 
ATOM   5350 H HH22 A ARG A 1 320 ? -30.750 -29.458 -21.476 0.500 11.571 0 335  ARG A HH22 1 c 
ATOM   5351 H HH22 B ARG A 1 320 ? -27.510 -26.415 -26.333 0.500 17.065 0 335  ARG A HH22 1 c 
ATOM   5352 N N    . GLU A 1 321 ? -26.336 -26.337 -20.908 1.000 12.100 0 336  GLU A N    1 ? 
ATOM   5353 C CA   . GLU A 1 321 ? -26.026 -24.918 -20.992 1.000 11.671 0 336  GLU A CA   1 ? 
ATOM   5354 C C    . GLU A 1 321 ? -24.608 -24.651 -20.477 1.000 10.484 0 336  GLU A C    1 ? 
ATOM   5355 O O    . GLU A 1 321 ? -23.957 -23.735 -20.974 1.000 10.212 0 336  GLU A O    1 ? 
ATOM   5356 C CB   . GLU A 1 321 ? -27.079 -24.131 -20.204 1.000 12.698 0 336  GLU A CB   1 ? 
ATOM   5357 C CG   . GLU A 1 321 ? -28.460 -24.254 -20.833 1.000 15.843 0 336  GLU A CG   1 ? 
ATOM   5358 C CD   . GLU A 1 321 ? -28.519 -23.927 -22.281 1.000 21.601 0 336  GLU A CD   1 ? 
ATOM   5359 O OE1  . GLU A 1 321 ? -27.714 -23.120 -22.801 1.000 23.861 0 336  GLU A OE1  1 ? 
ATOM   5360 O OE2  . GLU A 1 321 ? -29.437 -24.529 -22.912 1.000 26.828 0 336  GLU A OE2  1 ? 
ATOM   5361 H H    . GLU A 1 321 ? -26.886 -26.632 -20.240 1.000 11.706 0 336  GLU A H    1 c 
ATOM   5362 H HA   . GLU A 1 321 ? -26.065 -24.646 -21.942 1.000 11.782 0 336  GLU A HA   1 c 
ATOM   5363 H HB2  . GLU A 1 321 ? -27.102 -24.460 -19.281 1.000 13.090 0 336  GLU A HB2  1 c 
ATOM   5364 H HB3  . GLU A 1 321 ? -26.820 -23.188 -20.183 1.000 13.093 0 336  GLU A HB3  1 c 
ATOM   5365 H HG2  . GLU A 1 321 ? -28.783 -25.172 -20.709 1.000 16.243 0 336  GLU A HG2  1 c 
ATOM   5366 H HG3  . GLU A 1 321 ? -29.078 -23.660 -20.357 1.000 16.219 0 336  GLU A HG3  1 c 
ATOM   5367 N N    . ALA A 1 322 ? -24.131 -25.462 -19.540 1.000 9.902  0 337  ALA A N    1 ? 
ATOM   5368 C CA   . ALA A 1 322 ? -22.740 -25.356 -19.096 1.000 9.252  0 337  ALA A CA   1 ? 
ATOM   5369 C C    . ALA A 1 322 ? -21.797 -25.733 -20.246 1.000 9.100  0 337  ALA A C    1 ? 
ATOM   5370 O O    . ALA A 1 322 ? -20.850 -25.001 -20.541 1.000 8.479  0 337  ALA A O    1 ? 
ATOM   5371 C CB   . ALA A 1 322 ? -22.501 -26.192 -17.886 1.000 9.552  0 337  ALA A CB   1 ? 
ATOM   5372 H H    . ALA A 1 322 ? -24.674 -26.089 -19.156 1.000 9.910  0 337  ALA A H    1 c 
ATOM   5373 H HA   . ALA A 1 322 ? -22.567 -24.402 -18.861 1.000 9.411  0 337  ALA A HA   1 c 
ATOM   5374 H HB1  . ALA A 1 322 ? -23.081 -25.896 -17.164 1.000 9.461  0 337  ALA A HB1  1 c 
ATOM   5375 H HB2  . ALA A 1 322 ? -22.692 -27.123 -18.089 1.000 9.461  0 337  ALA A HB2  1 c 
ATOM   5376 H HB3  . ALA A 1 322 ? -21.574 -26.108 -17.608 1.000 9.461  0 337  ALA A HB3  1 c 
ATOM   5377 N N    . LEU A 1 323 ? -22.097 -26.860 -20.926 1.000 8.596  0 338  LEU A N    1 ? 
ATOM   5378 C CA   . LEU A 1 323 ? -21.295 -27.261 -22.072 1.000 8.572  0 338  LEU A CA   1 ? 
ATOM   5379 C C    . LEU A 1 323 ? -21.295 -26.179 -23.154 1.000 8.626  0 338  LEU A C    1 ? 
ATOM   5380 O O    . LEU A 1 323 ? -20.245 -25.940 -23.768 1.000 9.104  0 338  LEU A O    1 ? 
ATOM   5381 C CB   . LEU A 1 323 ? -21.742 -28.619 -22.608 1.000 9.815  0 338  LEU A CB   1 ? 
ATOM   5382 C CG   . LEU A 1 323 ? -21.450 -29.839 -21.722 1.000 10.189 0 338  LEU A CG   1 ? 
ATOM   5383 C CD1  . LEU A 1 323 ? -22.196 -31.041 -22.321 1.000 10.947 0 338  LEU A CD1  1 ? 
ATOM   5384 C CD2  . LEU A 1 323 ? -19.987 -30.126 -21.651 1.000 11.800 0 338  LEU A CD2  1 ? 
ATOM   5385 H H    . LEU A 1 323 ? -22.802 -27.381 -20.667 1.000 8.726  0 338  LEU A H    1 c 
ATOM   5386 H HA   . LEU A 1 323 ? -20.361 -27.348 -21.754 1.000 8.840  0 338  LEU A HA   1 c 
ATOM   5387 H HB2  . LEU A 1 323 ? -22.713 -28.579 -22.770 1.000 9.609  0 338  LEU A HB2  1 c 
ATOM   5388 H HB3  . LEU A 1 323 ? -21.307 -28.761 -23.481 1.000 9.593  0 338  LEU A HB3  1 c 
ATOM   5389 H HG   . LEU A 1 323 ? -21.793 -29.663 -20.809 1.000 10.550 0 338  LEU A HG   1 c 
ATOM   5390 H HD11 . LEU A 1 323 ? -23.152 -30.865 -22.317 1.000 10.712 0 338  LEU A HD11 1 c 
ATOM   5391 H HD12 . LEU A 1 323 ? -22.011 -31.834 -21.792 1.000 10.718 0 338  LEU A HD12 1 c 
ATOM   5392 H HD13 . LEU A 1 323 ? -21.898 -31.185 -23.235 1.000 10.718 0 338  LEU A HD13 1 c 
ATOM   5393 H HD21 . LEU A 1 323 ? -19.533 -29.396 -21.199 1.000 11.256 0 338  LEU A HD21 1 c 
ATOM   5394 H HD22 . LEU A 1 323 ? -19.630 -30.221 -22.551 1.000 11.282 0 338  LEU A HD22 1 c 
ATOM   5395 H HD23 . LEU A 1 323 ? -19.842 -30.951 -21.158 1.000 11.282 0 338  LEU A HD23 1 c 
ATOM   5396 N N    . GLN A 1 324 ? -22.461 -25.612 -23.451 1.000 9.229  0 339  GLN A N    1 ? 
ATOM   5397 C CA   . GLN A 1 324 ? -22.493 -24.552 -24.435 1.000 10.893 0 339  GLN A CA   1 ? 
ATOM   5398 C C    . GLN A 1 324 ? -21.580 -23.390 -24.074 1.000 10.023 0 339  GLN A C    1 ? 
ATOM   5399 O O    . GLN A 1 324 ? -20.896 -22.846 -24.944 1.000 10.519 0 339  GLN A O    1 ? 
ATOM   5400 C CB   . GLN A 1 324 ? -23.922 -24.080 -24.628 1.000 13.540 0 339  GLN A CB   1 ? 
ATOM   5401 C CG   . GLN A 1 324 ? -23.997 -22.978 -25.667 1.000 18.601 0 339  GLN A CG   1 ? 
ATOM   5402 C CD   . GLN A 1 324 ? -25.392 -22.876 -26.190 1.000 25.693 0 339  GLN A CD   1 ? 
ATOM   5403 O OE1  . GLN A 1 324 ? -26.318 -22.573 -25.437 1.000 33.555 0 339  GLN A OE1  1 ? 
ATOM   5404 N NE2  . GLN A 1 324 ? -25.558 -23.275 -27.430 1.000 25.607 0 339  GLN A NE2  1 ? 
ATOM   5405 H H    . GLN A 1 324 ? -23.235 -25.884 -23.049 1.000 9.440  0 339  GLN A H    1 c 
ATOM   5406 H HA   . GLN A 1 324 ? -22.182 -24.930 -25.297 1.000 10.833 0 339  GLN A HA   1 c 
ATOM   5407 H HB2  . GLN A 1 324 ? -24.477 -24.837 -24.913 1.000 13.909 0 339  GLN A HB2  1 c 
ATOM   5408 H HB3  . GLN A 1 324 ? -24.272 -23.749 -23.775 1.000 13.868 0 339  GLN A HB3  1 c 
ATOM   5409 H HG2  . GLN A 1 324 ? -23.739 -22.122 -25.262 1.000 18.583 0 339  GLN A HG2  1 c 
ATOM   5410 H HG3  . GLN A 1 324 ? -23.376 -23.169 -26.401 1.000 18.549 0 339  GLN A HG3  1 c 
ATOM   5411 H HE21 . GLN A 1 324 ? -24.866 -23.546 -27.914 1.000 25.395 0 339  GLN A HE21 1 c 
ATOM   5412 H HE22 . GLN A 1 324 ? -26.370 -23.273 -27.786 1.000 25.627 0 339  GLN A HE22 1 c 
ATOM   5413 N N    . ALA A 1 325 ? -21.666 -22.923 -22.817 1.000 9.137  0 340  ALA A N    1 ? 
ATOM   5414 C CA   . ALA A 1 325 ? -20.853 -21.786 -22.399 1.000 8.743  0 340  ALA A CA   1 ? 
ATOM   5415 C C    . ALA A 1 325 ? -19.345 -22.108 -22.406 1.000 10.317 0 340  ALA A C    1 ? 
ATOM   5416 O O    . ALA A 1 325 ? -18.543 -21.274 -22.803 1.000 10.907 0 340  ALA A O    1 ? 
ATOM   5417 C CB   . ALA A 1 325 ? -21.335 -21.366 -21.022 1.000 9.251  0 340  ALA A CB   1 ? 
ATOM   5418 H H    . ALA A 1 325 ? -22.235 -23.313 -22.218 1.000 9.259  0 340  ALA A H    1 c 
ATOM   5419 H HA   . ALA A 1 325 ? -21.013 -21.038 -23.039 1.000 9.192  0 340  ALA A HA   1 c 
ATOM   5420 H HB1  . ALA A 1 325 ? -22.264 -21.084 -21.073 1.000 9.098  0 340  ALA A HB1  1 c 
ATOM   5421 H HB2  . ALA A 1 325 ? -21.260 -22.115 -20.407 1.000 9.098  0 340  ALA A HB2  1 c 
ATOM   5422 H HB3  . ALA A 1 325 ? -20.792 -20.628 -20.697 1.000 9.098  0 340  ALA A HB3  1 c 
ATOM   5423 N N    . TRP A 1 326 ? -18.971 -23.311 -22.019 1.000 9.623  0 341  TRP A N    1 ? 
ATOM   5424 C CA   . TRP A 1 326 ? -17.543 -23.703 -22.110 1.000 9.707  0 341  TRP A CA   1 ? 
ATOM   5425 C C    . TRP A 1 326 ? -17.107 -23.879 -23.567 1.000 9.896  0 341  TRP A C    1 ? 
ATOM   5426 O O    . TRP A 1 326 ? -15.969 -23.447 -23.912 1.000 10.714 0 341  TRP A O    1 ? 
ATOM   5427 C CB   . TRP A 1 326 ? -17.318 -25.009 -21.350 1.000 9.210  0 341  TRP A CB   1 ? 
ATOM   5428 C CG   . TRP A 1 326 ? -17.379 -24.895 -19.862 1.000 9.137  0 341  TRP A CG   1 ? 
ATOM   5429 C CD1  . TRP A 1 326 ? -16.835 -23.898 -19.091 1.000 10.291 0 341  TRP A CD1  1 ? 
ATOM   5430 C CD2  . TRP A 1 326 ? -17.947 -25.825 -18.936 1.000 9.781  0 341  TRP A CD2  1 ? 
ATOM   5431 N NE1  . TRP A 1 326 ? -17.038 -24.175 -17.785 1.000 11.403 0 341  TRP A NE1  1 ? 
ATOM   5432 C CE2  . TRP A 1 326 ? -17.711 -25.342 -17.630 1.000 10.537 0 341  TRP A CE2  1 ? 
ATOM   5433 C CE3  . TRP A 1 326 ? -18.641 -27.035 -19.088 1.000 10.483 0 341  TRP A CE3  1 ? 
ATOM   5434 C CZ2  . TRP A 1 326 ? -18.206 -26.006 -16.514 1.000 11.745 0 341  TRP A CZ2  1 ? 
ATOM   5435 C CZ3  . TRP A 1 326 ? -19.125 -27.686 -17.986 1.000 11.295 0 341  TRP A CZ3  1 ? 
ATOM   5436 C CH2  . TRP A 1 326 ? -18.847 -27.196 -16.708 1.000 12.104 0 341  TRP A CH2  1 ? 
ATOM   5437 H H    . TRP A 1 326 ? -19.582 -23.905 -21.690 1.000 9.784  0 341  TRP A H    1 c 
ATOM   5438 H HA   . TRP A 1 326 ? -16.990 -22.992 -21.690 1.000 9.662  0 341  TRP A HA   1 c 
ATOM   5439 H HB2  . TRP A 1 326 ? -17.992 -25.658 -21.645 1.000 9.307  0 341  TRP A HB2  1 c 
ATOM   5440 H HB3  . TRP A 1 326 ? -16.440 -25.366 -21.602 1.000 9.307  0 341  TRP A HB3  1 c 
ATOM   5441 H HD1  . TRP A 1 326 ? -16.365 -23.151 -19.412 1.000 10.277 0 341  TRP A HD1  1 c 
ATOM   5442 H HE1  . TRP A 1 326 ? -16.789 -23.657 -17.128 1.000 10.906 0 341  TRP A HE1  1 c 
ATOM   5443 H HE3  . TRP A 1 326 ? -18.816 -27.370 -19.951 1.000 10.502 0 341  TRP A HE3  1 c 
ATOM   5444 H HZ2  . TRP A 1 326 ? -18.025 -25.687 -15.648 1.000 11.529 0 341  TRP A HZ2  1 c 
ATOM   5445 H HZ3  . TRP A 1 326 ? -19.574 -28.509 -18.085 1.000 11.263 0 341  TRP A HZ3  1 c 
ATOM   5446 H HH2  . TRP A 1 326 ? -19.172 -27.662 -15.963 1.000 11.824 0 341  TRP A HH2  1 c 
ATOM   5447 N N    . ALA A 1 327 ? -17.966 -24.334 -24.452 1.000 9.327  0 342  ALA A N    1 ? 
ATOM   5448 C CA   . ALA A 1 327 ? -17.620 -24.382 -25.882 1.000 9.797  0 342  ALA A CA   1 ? 
ATOM   5449 C C    . ALA A 1 327 ? -17.371 -22.945 -26.366 1.000 11.092 0 342  ALA A C    1 ? 
ATOM   5450 O O    . ALA A 1 327 ? -16.423 -22.678 -27.120 1.000 11.189 0 342  ALA A O    1 ? 
ATOM   5451 C CB   . ALA A 1 327 ? -18.687 -25.064 -26.679 1.000 10.531 0 342  ALA A CB   1 ? 
ATOM   5452 H H    . ALA A 1 327 ? -18.787 -24.632 -24.182 1.000 9.572  0 342  ALA A H    1 c 
ATOM   5453 H HA   . ALA A 1 327 ? -16.769 -24.892 -25.978 1.000 10.063 0 342  ALA A HA   1 c 
ATOM   5454 H HB1  . ALA A 1 327 ? -18.873 -25.938 -26.297 1.000 10.304 0 342  ALA A HB1  1 c 
ATOM   5455 H HB2  . ALA A 1 327 ? -19.498 -24.529 -26.665 1.000 10.348 0 342  ALA A HB2  1 c 
ATOM   5456 H HB3  . ALA A 1 327 ? -18.389 -25.172 -27.598 1.000 10.325 0 342  ALA A HB3  1 c 
ATOM   5457 N N    . ASP A 1 328 ? -18.225 -21.998 -25.938 1.000 11.123 0 343  ASP A N    1 ? 
ATOM   5458 C CA   . ASP A 1 328 ? -18.097 -20.596 -26.328 1.000 11.476 0 343  ASP A CA   1 ? 
ATOM   5459 C C    . ASP A 1 328 ? -16.812 -20.000 -25.760 1.000 10.855 0 343  ASP A C    1 ? 
ATOM   5460 O O    . ASP A 1 328 ? -16.161 -19.224 -26.496 1.000 12.380 0 343  ASP A O    1 ? 
ATOM   5461 C CB   . ASP A 1 328 ? -19.374 -19.844 -25.917 1.000 12.588 0 343  ASP A CB   1 ? 
ATOM   5462 C CG   . ASP A 1 328 ? -20.614 -20.134 -26.731 1.000 14.617 0 343  ASP A CG   1 ? 
ATOM   5463 O OD1  . ASP A 1 328 ? -20.519 -20.749 -27.838 1.000 15.738 0 343  ASP A OD1  1 ? 
ATOM   5464 O OD2  . ASP A 1 328 ? -21.749 -19.798 -26.224 1.000 17.082 0 343  ASP A OD2  1 ? 
ATOM   5465 H H    . ASP A 1 328 ? -18.915 -22.237 -25.390 1.000 11.190 0 343  ASP A H    1 c 
ATOM   5466 H HA   . ASP A 1 328 ? -18.041 -20.559 -27.309 1.000 11.508 0 343  ASP A HA   1 c 
ATOM   5467 H HB2  . ASP A 1 328 ? -19.573 -20.051 -24.980 1.000 12.741 0 343  ASP A HB2  1 c 
ATOM   5468 H HB3  . ASP A 1 328 ? -19.197 -18.882 -25.976 1.000 12.750 0 343  ASP A HB3  1 c 
ATOM   5469 N N    A MET A 1 329 ? -16.479 -20.343 -24.510 0.500 10.548 0 344  MET A N    1 ? 
ATOM   5470 N N    B MET A 1 329 ? -16.383 -20.346 -24.594 0.500 10.632 0 344  MET A N    1 ? 
ATOM   5471 C CA   A MET A 1 329 ? -15.200 -20.046 -23.849 0.500 10.706 0 344  MET A CA   1 ? 
ATOM   5472 C CA   B MET A 1 329 ? -15.150 -19.753 -24.127 0.500 11.552 0 344  MET A CA   1 ? 
ATOM   5473 C C    A MET A 1 329 ? -14.077 -20.361 -24.863 0.500 10.094 0 344  MET A C    1 ? 
ATOM   5474 C C    B MET A 1 329 ? -13.920 -20.351 -24.827 0.500 10.016 0 344  MET A C    1 ? 
ATOM   5475 O O    A MET A 1 329 ? -13.283 -19.542 -25.319 0.500 9.527  0 344  MET A O    1 ? 
ATOM   5476 O O    B MET A 1 329 ? -12.880 -19.680 -24.976 0.500 8.116  0 344  MET A O    1 ? 
ATOM   5477 C CB   A MET A 1 329 ? -14.944 -20.836 -22.530 0.500 11.366 0 344  MET A CB   1 ? 
ATOM   5478 C CB   B MET A 1 329 ? -15.126 -19.880 -22.617 0.500 12.671 0 344  MET A CB   1 ? 
ATOM   5479 C CG   A MET A 1 329 ? -15.089 -20.086 -21.191 0.500 12.922 0 344  MET A CG   1 ? 
ATOM   5480 C CG   B MET A 1 329 ? -13.988 -20.560 -22.028 0.500 12.056 0 344  MET A CG   1 ? 
ATOM   5481 S SD   A MET A 1 329 ? -15.028 -21.057 -19.668 0.500 13.526 0 344  MET A SD   1 ? 
ATOM   5482 S SD   B MET A 1 329 ? -14.545 -20.753 -20.338 0.500 13.885 0 344  MET A SD   1 ? 
ATOM   5483 C CE   A MET A 1 329 ? -13.809 -22.116 -20.401 0.500 8.715  0 344  MET A CE   1 ? 
ATOM   5484 C CE   B MET A 1 329 ? -13.036 -21.071 -19.416 0.500 16.090 0 344  MET A CE   1 ? 
ATOM   5485 H H    A MET A 1 329 ? -17.105 -20.795 -24.021 0.500 10.664 0 344  MET A H    1 c 
ATOM   5486 H H    B MET A 1 329 ? -16.838 -20.941 -24.070 0.500 10.887 0 344  MET A H    1 c 
ATOM   5487 H HA   A MET A 1 329 ? -15.177 -19.074 -23.654 0.500 10.674 0 344  MET A HA   1 c 
ATOM   5488 H HA   B MET A 1 329 ? -15.177 -18.788 -24.355 0.500 11.268 0 344  MET A HA   1 c 
ATOM   5489 H HB2  A MET A 1 329 ? -15.560 -21.597 -22.515 0.500 11.524 0 344  MET A HB2  1 c 
ATOM   5490 H HB2  B MET A 1 329 ? -15.168 -18.977 -22.240 0.500 12.230 0 344  MET A HB2  1 c 
ATOM   5491 H HB3  A MET A 1 329 ? -14.036 -21.205 -22.574 0.500 11.536 0 344  MET A HB3  1 c 
ATOM   5492 H HB3  B MET A 1 329 ? -15.942 -20.348 -22.339 0.500 12.255 0 344  MET A HB3  1 c 
ATOM   5493 H HG2  A MET A 1 329 ? -14.386 -19.410 -21.141 0.500 12.620 0 344  MET A HG2  1 c 
ATOM   5494 H HG2  B MET A 1 329 ? -13.834 -21.430 -22.446 0.500 12.528 0 344  MET A HG2  1 c 
ATOM   5495 H HG3  A MET A 1 329 ? -15.939 -19.613 -21.201 0.500 12.580 0 344  MET A HG3  1 c 
ATOM   5496 H HG3  B MET A 1 329 ? -13.180 -20.015 -22.071 0.500 12.516 0 344  MET A HG3  1 c 
ATOM   5497 H HE1  A MET A 1 329 ? -13.553 -22.807 -19.763 0.500 9.754  0 344  MET A HE1  1 c 
ATOM   5498 H HE1  B MET A 1 329 ? -13.250 -21.184 -18.472 0.500 15.508 0 344  MET A HE1  1 c 
ATOM   5499 H HE2  A MET A 1 329 ? -14.180 -22.533 -21.201 0.500 9.754  0 344  MET A HE2  1 c 
ATOM   5500 H HE2  B MET A 1 329 ? -12.614 -21.882 -19.754 0.500 15.508 0 344  MET A HE2  1 c 
ATOM   5501 H HE3  A MET A 1 329 ? -13.025 -21.590 -20.643 0.500 9.754  0 344  MET A HE3  1 c 
ATOM   5502 H HE3  B MET A 1 329 ? -12.425 -20.318 -19.523 0.500 15.508 0 344  MET A HE3  1 c 
ATOM   5503 N N    . ALA A 1 330 ? -14.026 -21.637 -25.243 1.000 10.274 0 345  ALA A N    1 ? 
ATOM   5504 C CA   . ALA A 1 330 ? -12.985 -22.181 -26.124 1.000 9.131  0 345  ALA A CA   1 ? 
ATOM   5505 C C    . ALA A 1 330 ? -12.926 -21.535 -27.495 1.000 9.445  0 345  ALA A C    1 ? 
ATOM   5506 O O    . ALA A 1 330 ? -11.862 -21.416 -28.111 1.000 9.479  0 345  ALA A O    1 ? 
ATOM   5507 C CB   . ALA A 1 330 ? -13.204 -23.685 -26.246 1.000 8.304  0 345  ALA A CB   1 ? 
ATOM   5508 H H    . ALA A 1 330 ? -14.698 -22.187 -24.957 1.000 9.980  0 345  ALA A H    1 c 
ATOM   5509 H HA   . ALA A 1 330 ? -12.105 -22.028 -25.681 1.000 9.227  0 345  ALA A HA   1 c 
ATOM   5510 H HB1  . ALA A 1 330 ? -13.206 -24.088 -25.362 1.000 8.536  0 345  ALA A HB1  1 c 
ATOM   5511 H HB2  . ALA A 1 330 ? -14.057 -23.857 -26.679 1.000 8.535  0 345  ALA A HB2  1 c 
ATOM   5512 H HB3  . ALA A 1 330 ? -12.491 -24.078 -26.776 1.000 8.526  0 345  ALA A HB3  1 c 
ATOM   5513 N N    . THR A 1 331 ? -14.073 -21.087 -27.997 1.000 9.318  0 346  THR A N    1 ? 
ATOM   5514 C CA   . THR A 1 331 ? -14.142 -20.438 -29.285 1.000 9.995  0 346  THR A CA   1 ? 
ATOM   5515 C C    . THR A 1 331 ? -13.464 -19.061 -29.211 1.000 9.313  0 346  THR A C    1 ? 
ATOM   5516 O O    . THR A 1 331 ? -12.882 -18.570 -30.209 1.000 11.081 0 346  THR A O    1 ? 
ATOM   5517 C CB   . THR A 1 331 ? -15.595 -20.369 -29.754 1.000 11.733 0 346  THR A CB   1 ? 
ATOM   5518 O OG1  . THR A 1 331 ? -16.001 -21.697 -30.107 1.000 13.084 0 346  THR A OG1  1 ? 
ATOM   5519 C CG2  . THR A 1 331 ? -15.756 -19.446 -30.935 1.000 13.474 0 346  THR A CG2  1 ? 
ATOM   5520 H H    . THR A 1 331 ? -14.844 -21.199 -27.520 1.000 9.541  0 346  THR A H    1 c 
ATOM   5521 H HA   . THR A 1 331 ? -13.644 -20.990 -29.928 1.000 10.036 0 346  THR A HA   1 c 
ATOM   5522 H HB   . THR A 1 331 ? -16.164 -20.042 -29.017 1.000 11.929 0 346  THR A HB   1 c 
ATOM   5523 H HG1  . THR A 1 331 ? -15.495 -21.994 -30.741 0.000 13.090 0 346  THR A HG1  1 c 
ATOM   5524 H HG21 . THR A 1 331 ? -16.623 -19.598 -31.349 1.000 12.920 0 346  THR A HG21 1 c 
ATOM   5525 H HG22 . THR A 1 331 ? -15.054 -19.622 -31.584 1.000 12.906 0 346  THR A HG22 1 c 
ATOM   5526 H HG23 . THR A 1 331 ? -15.699 -18.522 -30.638 1.000 12.903 0 346  THR A HG23 1 c 
ATOM   5527 N N    . VAL A 1 332 ? -13.451 -18.414 -28.047 1.000 8.783  0 347  VAL A N    1 ? 
ATOM   5528 C CA   . VAL A 1 332 ? -12.659 -17.208 -27.853 1.000 8.700  0 347  VAL A CA   1 ? 
ATOM   5529 C C    . VAL A 1 332 ? -11.180 -17.543 -27.754 1.000 8.826  0 347  VAL A C    1 ? 
ATOM   5530 O O    . VAL A 1 332 ? -10.337 -16.869 -28.379 1.000 8.818  0 347  VAL A O    1 ? 
ATOM   5531 C CB   . VAL A 1 332 ? -13.112 -16.429 -26.605 1.000 8.952  0 347  VAL A CB   1 ? 
ATOM   5532 C CG1  . VAL A 1 332 ? -12.238 -15.182 -26.419 1.000 9.965  0 347  VAL A CG1  1 ? 
ATOM   5533 C CG2  . VAL A 1 332 ? -14.584 -16.028 -26.684 1.000 10.354 0 347  VAL A CG2  1 ? 
ATOM   5534 H H    . VAL A 1 332 ? -13.953 -18.728 -27.351 1.000 8.912  0 347  VAL A H    1 c 
ATOM   5535 H HA   . VAL A 1 332 ? -12.789 -16.632 -28.631 1.000 8.799  0 347  VAL A HA   1 c 
ATOM   5536 H HB   . VAL A 1 332 ? -12.989 -17.018 -25.825 1.000 9.353  0 347  VAL A HB   1 c 
ATOM   5537 H HG11 . VAL A 1 332 ? -12.153 -14.715 -27.268 1.000 9.657  0 347  VAL A HG11 1 c 
ATOM   5538 H HG12 . VAL A 1 332 ? -11.357 -15.444 -26.104 1.000 9.654  0 347  VAL A HG12 1 c 
ATOM   5539 H HG13 . VAL A 1 332 ? -12.650 -14.591 -25.766 1.000 9.661  0 347  VAL A HG13 1 c 
ATOM   5540 H HG21 . VAL A 1 332 ? -14.818 -15.496 -25.906 1.000 9.910  0 347  VAL A HG21 1 c 
ATOM   5541 H HG22 . VAL A 1 332 ? -15.139 -16.826 -26.707 1.000 9.916  0 347  VAL A HG22 1 c 
ATOM   5542 H HG23 . VAL A 1 332 ? -14.736 -15.506 -27.490 1.000 9.917  0 347  VAL A HG23 1 c 
ATOM   5543 N N    . ILE A 1 333 ? -10.790 -18.509 -26.909 1.000 8.179  0 348  ILE A N    1 ? 
ATOM   5544 C CA   . ILE A 1 333 ? -9.363  -18.773 -26.679 1.000 8.509  0 348  ILE A CA   1 ? 
ATOM   5545 C C    . ILE A 1 333 ? -8.643  -19.246 -27.946 1.000 8.350  0 348  ILE A C    1 ? 
ATOM   5546 O O    . ILE A 1 333 ? -7.424  -19.044 -28.038 1.000 9.306  0 348  ILE A O    1 ? 
ATOM   5547 C CB   . ILE A 1 333 ? -9.106  -19.750 -25.504 1.000 8.026  0 348  ILE A CB   1 ? 
ATOM   5548 C CG1  . ILE A 1 333 ? -7.752  -19.545 -24.817 1.000 8.629  0 348  ILE A CG1  1 ? 
ATOM   5549 C CG2  . ILE A 1 333 ? -9.286  -21.186 -25.944 1.000 7.988  0 348  ILE A CG2  1 ? 
ATOM   5550 C CD1  . ILE A 1 333 ? -7.535  -18.206 -24.140 1.000 9.517  0 348  ILE A CD1  1 ? 
ATOM   5551 H H    . ILE A 1 333 ? -11.413 -19.011 -26.468 1.000 8.406  0 348  ILE A H    1 c 
ATOM   5552 H HA   . ILE A 1 333 ? -8.961  -17.921 -26.428 1.000 8.338  0 348  ILE A HA   1 c 
ATOM   5553 H HB   . ILE A 1 333 ? -9.793  -19.569 -24.831 1.000 8.217  0 348  ILE A HB   1 c 
ATOM   5554 H HG12 . ILE A 1 333 ? -7.640  -20.249 -24.146 1.000 8.682  0 348  ILE A HG12 1 c 
ATOM   5555 H HG13 . ILE A 1 333 ? -7.050  -19.665 -25.487 1.000 8.682  0 348  ILE A HG13 1 c 
ATOM   5556 H HG21 . ILE A 1 333 ? -9.366  -21.758 -25.162 1.000 8.009  0 348  ILE A HG21 1 c 
ATOM   5557 H HG22 . ILE A 1 333 ? -8.519  -21.467 -26.469 1.000 8.005  0 348  ILE A HG22 1 c 
ATOM   5558 H HG23 . ILE A 1 333 ? -10.090 -21.263 -26.482 1.000 8.019  0 348  ILE A HG23 1 c 
ATOM   5559 H HD11 . ILE A 1 333 ? -7.499  -17.497 -24.810 1.000 9.238  0 348  ILE A HD11 1 c 
ATOM   5560 H HD12 . ILE A 1 333 ? -6.693  -18.226 -23.647 1.000 9.243  0 348  ILE A HD12 1 c 
ATOM   5561 H HD13 . ILE A 1 333 ? -8.269  -18.030 -23.521 1.000 9.244  0 348  ILE A HD13 1 c 
ATOM   5562 N N    . GLN A 1 334 ? -9.365  -19.825 -28.901 1.000 8.534  0 349  GLN A N    1 ? 
ATOM   5563 C CA   . GLN A 1 334 ? -8.709  -20.408 -30.073 1.000 9.338  0 349  GLN A CA   1 ? 
ATOM   5564 C C    . GLN A 1 334 ? -7.877  -19.419 -30.871 1.000 9.405  0 349  GLN A C    1 ? 
ATOM   5565 O O    . GLN A 1 334 ? -6.964  -19.843 -31.592 1.000 10.280 0 349  GLN A O    1 ? 
ATOM   5566 C CB   . GLN A 1 334 ? -9.741  -21.075 -30.953 1.000 10.665 0 349  GLN A CB   1 ? 
ATOM   5567 C CG   . GLN A 1 334 ? -10.550 -20.155 -31.837 1.000 13.247 0 349  GLN A CG   1 ? 
ATOM   5568 C CD   . GLN A 1 334 ? -11.555 -20.956 -32.622 1.000 17.408 0 349  GLN A CD   1 ? 
ATOM   5569 O OE1  . GLN A 1 334 ? -11.367 -22.161 -32.797 1.000 20.091 0 349  GLN A OE1  1 ? 
ATOM   5570 N NE2  . GLN A 1 334 ? -12.665 -20.335 -32.948 1.000 22.457 0 349  GLN A NE2  1 ? 
ATOM   5571 H H    . GLN A 1 334 ? -10.274 -19.874 -28.827 1.000 8.687  0 349  GLN A H    1 c 
ATOM   5572 H HA   . GLN A 1 334 ? -8.098  -21.119 -29.749 1.000 9.420  0 349  GLN A HA   1 c 
ATOM   5573 H HB2  . GLN A 1 334 ? -9.277  -21.720 -31.521 1.000 10.922 0 349  GLN A HB2  1 c 
ATOM   5574 H HB3  . GLN A 1 334 ? -10.355 -21.579 -30.380 1.000 10.913 0 349  GLN A HB3  1 c 
ATOM   5575 H HG2  . GLN A 1 334 ? -11.010 -19.489 -31.287 1.000 13.483 0 349  GLN A HG2  1 c 
ATOM   5576 H HG3  . GLN A 1 334 ? -9.956  -19.683 -32.459 1.000 13.415 0 349  GLN A HG3  1 c 
ATOM   5577 H HE21 . GLN A 1 334 ? -12.725 -19.453 -32.865 1.000 20.613 0 349  GLN A HE21 1 c 
ATOM   5578 H HE22 . GLN A 1 334 ? -13.356 -20.800 -33.255 1.000 20.721 0 349  GLN A HE22 1 c 
ATOM   5579 N N    . ASP A 1 335 ? -8.239  -18.125 -30.823 1.000 8.460  0 350  ASP A N    1 ? 
ATOM   5580 C CA   . ASP A 1 335 ? -7.544  -17.094 -31.592 1.000 9.896  0 350  ASP A CA   1 ? 
ATOM   5581 C C    . ASP A 1 335 ? -6.424  -16.434 -30.811 1.000 10.558 0 350  ASP A C    1 ? 
ATOM   5582 O O    . ASP A 1 335 ? -5.969  -15.359 -31.218 1.000 14.301 0 350  ASP A O    1 ? 
ATOM   5583 C CB   . ASP A 1 335 ? -8.580  -16.111 -32.132 1.000 12.213 0 350  ASP A CB   1 ? 
ATOM   5584 C CG   . ASP A 1 335 ? -9.441  -16.697 -33.240 1.000 17.117 0 350  ASP A CG   1 ? 
ATOM   5585 O OD1  . ASP A 1 335 ? -8.849  -17.333 -34.117 1.000 20.666 0 350  ASP A OD1  1 ? 
ATOM   5586 O OD2  . ASP A 1 335 ? -10.664 -16.503 -33.214 1.000 21.612 0 350  ASP A OD2  1 ? 
ATOM   5587 H H    . ASP A 1 335 ? -8.949  -17.877 -30.305 1.000 9.025  0 350  ASP A H    1 c 
ATOM   5588 H HA   . ASP A 1 335 ? -7.139  -17.525 -32.377 1.000 10.178 0 350  ASP A HA   1 c 
ATOM   5589 H HB2  . ASP A 1 335 ? -9.164  -15.822 -31.401 1.000 12.613 0 350  ASP A HB2  1 c 
ATOM   5590 H HB3  . ASP A 1 335 ? -8.123  -15.322 -32.489 1.000 12.605 0 350  ASP A HB3  1 c 
ATOM   5591 N N    . TYR A 1 336 ? -6.012  -16.941 -29.659 1.000 9.293  0 351  TYR A N    1 ? 
ATOM   5592 C CA   . TYR A 1 336 ? -4.874  -16.522 -28.865 1.000 8.847  0 351  TYR A CA   1 ? 
ATOM   5593 C C    . TYR A 1 336 ? -3.697  -17.458 -29.111 1.000 9.678  0 351  TYR A C    1 ? 
ATOM   5594 O O    . TYR A 1 336 ? -3.897  -18.621 -29.508 1.000 10.012 0 351  TYR A O    1 ? 
ATOM   5595 C CB   . TYR A 1 336 ? -5.258  -16.465 -27.395 1.000 8.896  0 351  TYR A CB   1 ? 
ATOM   5596 C CG   . TYR A 1 336 ? -6.087  -15.255 -27.006 1.000 8.073  0 351  TYR A CG   1 ? 
ATOM   5597 C CD1  . TYR A 1 336 ? -5.439  -14.085 -26.693 1.000 7.837  0 351  TYR A CD1  1 ? 
ATOM   5598 C CD2  . TYR A 1 336 ? -7.458  -15.263 -26.965 1.000 7.743  0 351  TYR A CD2  1 ? 
ATOM   5599 C CE1  . TYR A 1 336 ? -6.127  -12.959 -26.296 1.000 8.023  0 351  TYR A CE1  1 ? 
ATOM   5600 C CE2  . TYR A 1 336 ? -8.167  -14.134 -26.592 1.000 7.322  0 351  TYR A CE2  1 ? 
ATOM   5601 C CZ   . TYR A 1 336 ? -7.511  -12.971 -26.236 1.000 7.846  0 351  TYR A CZ   1 ? 
ATOM   5602 O OH   . TYR A 1 336 ? -8.130  -11.807 -25.864 1.000 8.607  0 351  TYR A OH   1 ? 
ATOM   5603 H H    . TYR A 1 336 ? -6.506  -17.634 -29.325 1.000 9.454  0 351  TYR A H    1 c 
ATOM   5604 H HA   . TYR A 1 336 ? -4.612  -15.607 -29.153 1.000 9.120  0 351  TYR A HA   1 c 
ATOM   5605 H HB2  . TYR A 1 336 ? -5.761  -17.279 -27.172 1.000 8.698  0 351  TYR A HB2  1 c 
ATOM   5606 H HB3  . TYR A 1 336 ? -4.435  -16.469 -26.858 1.000 8.691  0 351  TYR A HB3  1 c 
ATOM   5607 H HD1  . TYR A 1 336 ? -4.496  -14.065 -26.701 1.000 7.952  0 351  TYR A HD1  1 c 
ATOM   5608 H HD2  . TYR A 1 336 ? -7.926  -16.053 -27.183 1.000 7.733  0 351  TYR A HD2  1 c 
ATOM   5609 H HE1  . TYR A 1 336 ? -5.656  -12.174 -26.076 1.000 7.934  0 351  TYR A HE1  1 c 
ATOM   5610 H HE2  . TYR A 1 336 ? -9.108  -14.165 -26.557 1.000 7.555  0 351  TYR A HE2  1 c 
ATOM   5611 H HH   . TYR A 1 336 ? -8.298  -11.328 -26.556 0.000 8.620  0 351  TYR A HH   1 c 
ATOM   5612 N N    . ASN A 1 337 ? -2.507  -16.974 -28.804 1.000 9.437  0 352  ASN A N    1 ? 
ATOM   5613 C CA   . ASN A 1 337 ? -1.326  -17.799 -28.616 1.000 10.807 0 352  ASN A CA   1 ? 
ATOM   5614 C C    . ASN A 1 337 ? -1.104  -18.022 -27.131 1.000 10.183 0 352  ASN A C    1 ? 
ATOM   5615 O O    . ASN A 1 337 ? -1.177  -17.057 -26.348 1.000 11.114 0 352  ASN A O    1 ? 
ATOM   5616 C CB   . ASN A 1 337 ? -0.083  -17.111 -29.204 1.000 13.434 0 352  ASN A CB   1 ? 
ATOM   5617 C CG   . ASN A 1 337 ? -0.073  -17.072 -30.703 1.000 18.366 0 352  ASN A CG   1 ? 
ATOM   5618 O OD1  . ASN A 1 337 ? -0.753  -17.874 -31.327 1.000 19.432 0 352  ASN A OD1  1 ? 
ATOM   5619 N ND2  . ASN A 1 337 ? 0.623   -16.084 -31.255 1.000 22.516 0 352  ASN A ND2  1 ? 
ATOM   5620 H H    . ASN A 1 337 ? -2.419  -16.069 -28.704 1.000 9.804  0 352  ASN A H    1 c 
ATOM   5621 H HA   . ASN A 1 337 ? -1.451  -18.663 -29.070 1.000 10.861 0 352  ASN A HA   1 c 
ATOM   5622 H HB2  . ASN A 1 337 ? -0.038  -16.196 -28.863 1.000 13.809 0 352  ASN A HB2  1 c 
ATOM   5623 H HB3  . ASN A 1 337 ? 0.716   -17.584 -28.896 1.000 13.750 0 352  ASN A HB3  1 c 
ATOM   5624 H HD21 . ASN A 1 337 ? 1.173   -15.594 -30.761 1.000 20.999 0 352  ASN A HD21 1 c 
ATOM   5625 H HD22 . ASN A 1 337 ? 0.536   -15.916 -32.122 1.000 21.111 0 352  ASN A HD22 1 c 
ATOM   5626 N N    . TYR A 1 338 ? -0.878  -19.271 -26.693 1.000 9.444  0 353  TYR A N    1 ? 
ATOM   5627 C CA   . TYR A 1 338 ? -0.591  -19.594 -25.316 1.000 9.958  0 353  TYR A CA   1 ? 
ATOM   5628 C C    . TYR A 1 338 ? 0.839   -19.196 -24.959 1.000 11.415 0 353  TYR A C    1 ? 
ATOM   5629 O O    . TYR A 1 338 ? 1.763   -19.829 -25.461 1.000 12.547 0 353  TYR A O    1 ? 
ATOM   5630 C CB   . TYR A 1 338 ? -0.840  -21.097 -25.052 1.000 10.830 0 353  TYR A CB   1 ? 
ATOM   5631 C CG   . TYR A 1 338 ? -0.594  -21.460 -23.605 1.000 10.935 0 353  TYR A CG   1 ? 
ATOM   5632 C CD1  . TYR A 1 338 ? -1.144  -20.731 -22.541 1.000 11.721 0 353  TYR A CD1  1 ? 
ATOM   5633 C CD2  . TYR A 1 338 ? 0.185   -22.549 -23.261 1.000 11.769 0 353  TYR A CD2  1 ? 
ATOM   5634 C CE1  . TYR A 1 338 ? -0.882  -21.022 -21.219 1.000 12.570 0 353  TYR A CE1  1 ? 
ATOM   5635 C CE2  . TYR A 1 338 ? 0.391   -22.897 -21.940 1.000 14.039 0 353  TYR A CE2  1 ? 
ATOM   5636 C CZ   . TYR A 1 338 ? -0.103  -22.109 -20.914 1.000 14.557 0 353  TYR A CZ   1 ? 
ATOM   5637 O OH   . TYR A 1 338 ? 0.119   -22.408 -19.586 1.000 15.473 0 353  TYR A OH   1 ? 
ATOM   5638 H H    . TYR A 1 338 ? -0.911  -19.955 -27.298 1.000 9.771  0 353  TYR A H    1 c 
ATOM   5639 H HA   . TYR A 1 338 ? -1.211  -19.074 -24.744 1.000 10.287 0 353  TYR A HA   1 c 
ATOM   5640 H HB2  . TYR A 1 338 ? -1.770  -21.312 -25.287 1.000 10.656 0 353  TYR A HB2  1 c 
ATOM   5641 H HB3  . TYR A 1 338 ? -0.241  -21.625 -25.626 1.000 10.675 0 353  TYR A HB3  1 c 
ATOM   5642 H HD1  . TYR A 1 338 ? -1.654  -19.961 -22.737 1.000 11.735 0 353  TYR A HD1  1 c 
ATOM   5643 H HD2  . TYR A 1 338 ? 0.553   -23.089 -23.943 1.000 12.065 0 353  TYR A HD2  1 c 
ATOM   5644 H HE1  . TYR A 1 338 ? -1.257  -20.498 -20.532 1.000 12.796 0 353  TYR A HE1  1 c 
ATOM   5645 H HE2  . TYR A 1 338 ? 0.948   -23.628 -21.734 1.000 13.550 0 353  TYR A HE2  1 c 
ATOM   5646 H HH   . TYR A 1 338 ? -0.490  -22.940 -19.300 0.000 15.510 0 353  TYR A HH   1 c 
ATOM   5647 N N    . CYS A 1 339 ? 1.025   -18.144 -24.188 1.000 10.433 0 354  CYS A N    1 ? 
ATOM   5648 C CA   . CYS A 1 339 ? 2.344   -17.564 -23.879 1.000 10.982 0 354  CYS A CA   1 ? 
ATOM   5649 C C    . CYS A 1 339 ? 2.700   -17.743 -22.405 1.000 12.491 0 354  CYS A C    1 ? 
ATOM   5650 O O    . CYS A 1 339 ? 1.845   -18.050 -21.548 1.000 12.972 0 354  CYS A O    1 ? 
ATOM   5651 C CB   . CYS A 1 339 ? 2.385   -16.105 -24.285 1.000 12.012 0 354  CYS A CB   1 ? 
ATOM   5652 S SG   . CYS A 1 339 ? 2.083   -15.800 -26.036 1.000 12.214 0 354  CYS A SG   1 ? 
ATOM   5653 H H    . CYS A 1 339 ? 0.289   -17.747 -23.819 1.000 10.772 0 354  CYS A H    1 c 
ATOM   5654 H HA   . CYS A 1 339 ? 3.021   -18.044 -24.420 1.000 11.336 0 354  CYS A HA   1 c 
ATOM   5655 H HB2  . CYS A 1 339 ? 1.711   -15.613 -23.766 1.000 11.797 0 354  CYS A HB2  1 c 
ATOM   5656 H HB3  . CYS A 1 339 ? 3.266   -15.735 -24.058 1.000 11.808 0 354  CYS A HB3  1 c 
ATOM   5657 H HG   . CYS A 1 339 ? 2.186   -14.593 -26.007 0.000 12.220 0 354  CYS A HG   1 c 
ATOM   5658 N N    A ARG A 1 340 ? 4.019   -17.704 -22.137 0.500 12.338 0 355  ARG A N    1 ? 
ATOM   5659 N N    B ARG A 1 340 ? 3.930   -17.378 -22.016 0.500 12.955 0 355  ARG A N    1 ? 
ATOM   5660 C CA   A ARG A 1 340 ? 4.559   -17.406 -20.825 0.500 12.240 0 355  ARG A CA   1 ? 
ATOM   5661 C CA   B ARG A 1 340 ? 4.503   -17.895 -20.787 0.500 13.380 0 355  ARG A CA   1 ? 
ATOM   5662 C C    A ARG A 1 340 ? 3.699   -16.328 -20.201 0.500 11.707 0 355  ARG A C    1 ? 
ATOM   5663 C C    B ARG A 1 340 ? 3.973   -17.238 -19.510 0.500 12.724 0 355  ARG A C    1 ? 
ATOM   5664 O O    A ARG A 1 340 ? 3.572   -15.276 -20.811 0.500 11.816 0 355  ARG A O    1 ? 
ATOM   5665 O O    B ARG A 1 340 ? 4.281   -17.752 -18.433 0.500 14.627 0 355  ARG A O    1 ? 
ATOM   5666 C CB   A ARG A 1 340 ? 6.009   -16.878 -20.906 0.500 12.789 0 355  ARG A CB   1 ? 
ATOM   5667 C CB   B ARG A 1 340 ? 6.032   -17.767 -20.757 0.500 12.572 0 355  ARG A CB   1 ? 
ATOM   5668 H H    A ARG A 1 340 ? 4.607   -17.877 -22.816 0.500 12.333 0 355  ARG A H    1 c 
ATOM   5669 H H    B ARG A 1 340 ? 4.421   -16.801 -22.527 0.500 12.907 0 355  ARG A H    1 c 
ATOM   5670 H HA   A ARG A 1 340 ? 4.521   -18.224 -20.268 0.500 12.254 0 355  ARG A HA   1 c 
ATOM   5671 H HA   B ARG A 1 340 ? 4.288   -18.861 -20.740 0.500 13.151 0 355  ARG A HA   1 c 
ATOM   5672 H HB2  A ARG A 1 340 ? 6.115   -16.378 -21.743 0.500 12.709 0 355  ARG A HB2  1 c 
ATOM   5673 H HB2  B ARG A 1 340 ? 6.306   -17.115 -21.437 0.500 12.804 0 355  ARG A HB2  1 c 
ATOM   5674 H HB3  A ARG A 1 340 ? 6.157   -16.252 -20.165 0.500 12.646 0 355  ARG A HB3  1 c 
ATOM   5675 H HB3  B ARG A 1 340 ? 6.301   -17.415 -19.882 0.500 12.804 0 355  ARG A HB3  1 c 
ATOM   5676 N N    A GLU A 1 341 ? 3.190   -16.597 -18.995 0.500 11.155 0 356  GLU A N    1 ? 
ATOM   5677 N N    B GLU A 1 341 ? 3.170   -16.164 -19.574 0.500 11.549 0 356  GLU A N    1 ? 
ATOM   5678 C CA   A GLU A 1 341 ? 2.444   -15.654 -18.173 0.500 11.389 0 356  GLU A CA   1 ? 
ATOM   5679 C CA   B GLU A 1 341 ? 2.514   -15.675 -18.357 0.500 10.546 0 356  GLU A CA   1 ? 
ATOM   5680 C C    A GLU A 1 341 ? 0.932   -15.778 -18.395 0.500 9.502  0 356  GLU A C    1 ? 
ATOM   5681 C C    B GLU A 1 341 ? 0.985   -15.847 -18.361 0.500 9.051  0 356  GLU A C    1 ? 
ATOM   5682 O O    A GLU A 1 341 ? 0.176   -15.013 -17.798 0.500 9.258  0 356  GLU A O    1 ? 
ATOM   5683 O O    B GLU A 1 341 ? 0.286   -15.274 -17.517 0.500 8.143  0 356  GLU A O    1 ? 
ATOM   5684 C CB   A GLU A 1 341 ? 2.860   -14.198 -18.358 0.500 12.327 0 356  GLU A CB   1 ? 
ATOM   5685 C CB   B GLU A 1 341 ? 2.863   -14.231 -18.017 0.500 10.543 0 356  GLU A CB   1 ? 
ATOM   5686 C CG   A GLU A 1 341 ? 4.334   -13.888 -18.080 0.500 14.001 0 356  GLU A CG   1 ? 
ATOM   5687 C CG   B GLU A 1 341 ? 4.248   -14.084 -17.385 0.500 11.349 0 356  GLU A CG   1 ? 
ATOM   5688 C CD   A GLU A 1 341 ? 4.452   -12.493 -17.473 0.500 16.355 0 356  GLU A CD   1 ? 
ATOM   5689 C CD   B GLU A 1 341 ? 4.687   -12.646 -17.189 0.500 12.238 0 356  GLU A CD   1 ? 
ATOM   5690 O OE1  A GLU A 1 341 ? 4.882   -11.600 -18.227 0.500 21.226 0 356  GLU A OE1  1 ? 
ATOM   5691 O OE1  B GLU A 1 341 ? 3.865   -11.848 -16.686 0.500 10.531 0 356  GLU A OE1  1 ? 
ATOM   5692 O OE2  A GLU A 1 341 ? 4.092   -12.274 -16.283 0.500 17.115 0 356  GLU A OE2  1 ? 
ATOM   5693 O OE2  B GLU A 1 341 ? 5.861   -12.342 -17.534 0.500 15.078 0 356  GLU A OE2  1 ? 
ATOM   5694 H H    A GLU A 1 341 ? 3.319   -17.439 -18.662 0.500 11.337 0 356  GLU A H    1 c 
ATOM   5695 H H    B GLU A 1 341 ? 3.032   -15.733 -20.368 0.500 11.589 0 356  GLU A H    1 c 
ATOM   5696 H HA   A GLU A 1 341 ? 2.625   -15.884 -17.227 0.500 11.212 0 356  GLU A HA   1 c 
ATOM   5697 H HA   B GLU A 1 341 ? 2.861   -16.220 -17.606 0.500 10.436 0 356  GLU A HA   1 c 
ATOM   5698 H HB2  A GLU A 1 341 ? 2.658   -13.928 -19.276 0.500 12.481 0 356  GLU A HB2  1 c 
ATOM   5699 H HB2  B GLU A 1 341 ? 2.826   -13.696 -18.837 0.500 10.720 0 356  GLU A HB2  1 c 
ATOM   5700 H HB3  A GLU A 1 341 ? 2.317   -13.643 -17.761 0.500 12.476 0 356  GLU A HB3  1 c 
ATOM   5701 H HB3  B GLU A 1 341 ? 2.189   -13.880 -17.400 0.500 10.717 0 356  GLU A HB3  1 c 
ATOM   5702 H HG2  A GLU A 1 341 ? 4.701   -14.547 -17.453 0.500 14.096 0 356  GLU A HG2  1 c 
ATOM   5703 H HG2  B GLU A 1 341 ? 4.250   -14.533 -16.515 0.500 11.469 0 356  GLU A HG2  1 c 
ATOM   5704 H HG3  A GLU A 1 341 ? 4.845   -13.922 -18.916 0.500 14.096 0 356  GLU A HG3  1 c 
ATOM   5705 H HG3  B GLU A 1 341 ? 4.908   -14.536 -17.953 0.500 11.379 0 356  GLU A HG3  1 c 
ATOM   5706 N N    . ASP A 1 342 ? 0.498   -16.739 -19.233 1.000 9.009  0 357  ASP A N    1 ? 
ATOM   5707 C CA   . ASP A 1 342 ? -0.920  -17.057 -19.403 1.000 8.090  0 357  ASP A CA   1 ? 
ATOM   5708 C C    . ASP A 1 342 ? -1.374  -18.237 -18.534 1.000 8.410  0 357  ASP A C    1 ? 
ATOM   5709 O O    . ASP A 1 342 ? -2.460  -18.759 -18.717 1.000 8.947  0 357  ASP A O    1 ? 
ATOM   5710 C CB   . ASP A 1 342 ? -1.261  -17.343 -20.851 1.000 7.899  0 357  ASP A CB   1 ? 
ATOM   5711 C CG   . ASP A 1 342 ? -1.208  -16.169 -21.788 1.000 8.297  0 357  ASP A CG   1 ? 
ATOM   5712 O OD1  . ASP A 1 342 ? -1.164  -15.024 -21.283 1.000 8.747  0 357  ASP A OD1  1 ? 
ATOM   5713 O OD2  . ASP A 1 342 ? -1.279  -16.392 -23.023 1.000 9.623  0 357  ASP A OD2  1 ? 
ATOM   5714 H H    . ASP A 1 342 ? 1.096   -17.205 -19.743 1.000 9.003  0 357  ASP A H    1 c 
ATOM   5715 H HA   . ASP A 1 342 ? -1.446  -16.268 -19.140 1.000 8.299  0 357  ASP A HA   1 c 
ATOM   5716 H HB2  . ASP A 1 342 ? -0.650  -18.031 -21.188 1.000 8.058  0 357  ASP A HB2  1 c 
ATOM   5717 H HB3  . ASP A 1 342 ? -2.169  -17.707 -20.898 1.000 8.046  0 357  ASP A HB3  1 c 
ATOM   5718 N N    . GLU A 1 343 ? -0.569  -18.649 -17.556 1.000 8.980  0 358  GLU A N    1 ? 
ATOM   5719 C CA   . GLU A 1 343 ? -0.863  -19.910 -16.871 1.000 9.779  0 358  GLU A CA   1 ? 
ATOM   5720 C C    . GLU A 1 343 ? -2.197  -19.900 -16.137 1.000 9.095  0 358  GLU A C    1 ? 
ATOM   5721 O O    . GLU A 1 343 ? -2.776  -20.962 -15.939 1.000 9.331  0 358  GLU A O    1 ? 
ATOM   5722 C CB   . GLU A 1 343 ? 0.270   -20.321 -15.936 1.000 14.902 0 358  GLU A CB   1 ? 
ATOM   5723 C CG   . GLU A 1 343 ? 0.361   -19.679 -14.567 1.000 25.210 0 358  GLU A CG   1 ? 
ATOM   5724 C CD   . GLU A 1 343 ? 1.561   -20.182 -13.744 1.000 36.800 0 358  GLU A CD   1 ? 
ATOM   5725 O OE1  . GLU A 1 343 ? 1.385   -20.734 -12.628 1.000 36.592 0 358  GLU A OE1  1 ? 
ATOM   5726 O OE2  . GLU A 1 343 ? 2.698   -20.033 -14.253 1.000 50.604 0 358  GLU A OE2  1 ? 
ATOM   5727 H H    . GLU A 1 343 ? 0.155   -18.155 -17.300 1.000 9.081  0 358  GLU A H    1 c 
ATOM   5728 H HA   . GLU A 1 343 ? -0.917  -20.614 -17.566 1.000 10.264 0 358  GLU A HA   1 c 
ATOM   5729 H HB2  . GLU A 1 343 ? 0.211   -21.289 -15.795 1.000 15.332 0 358  GLU A HB2  1 c 
ATOM   5730 H HB3  . GLU A 1 343 ? 1.119   -20.145 -16.394 1.000 15.380 0 358  GLU A HB3  1 c 
ATOM   5731 H HG2  . GLU A 1 343 ? 0.436   -18.706 -14.671 1.000 24.274 0 358  GLU A HG2  1 c 
ATOM   5732 H HG3  . GLU A 1 343 ? -0.461  -19.866 -14.066 1.000 24.169 0 358  GLU A HG3  1 c 
ATOM   5733 N N    . GLU A 1 344 ? -2.706  -18.775 -15.670 1.000 9.141  0 359  GLU A N    1 ? 
ATOM   5734 C CA   . GLU A 1 344 ? -3.970  -18.799 -14.925 1.000 9.078  0 359  GLU A CA   1 ? 
ATOM   5735 C C    . GLU A 1 344 ? -5.116  -19.304 -15.814 1.000 9.242  0 359  GLU A C    1 ? 
ATOM   5736 O O    . GLU A 1 344 ? -5.977  -20.044 -15.318 1.000 9.499  0 359  GLU A O    1 ? 
ATOM   5737 C CB   . GLU A 1 344 ? -4.226  -17.420 -14.326 1.000 11.326 0 359  GLU A CB   1 ? 
ATOM   5738 C CG   . GLU A 1 344 ? -3.260  -17.158 -13.178 1.000 13.507 0 359  GLU A CG   1 ? 
ATOM   5739 C CD   . GLU A 1 344 ? -3.238  -18.155 -12.022 1.000 17.450 0 359  GLU A CD   1 ? 
ATOM   5740 O OE1  . GLU A 1 344 ? -4.299  -18.667 -11.628 1.000 19.411 0 359  GLU A OE1  1 ? 
ATOM   5741 O OE2  . GLU A 1 344 ? -2.094  -18.357 -11.563 1.000 26.514 0 359  GLU A OE2  1 ? 
ATOM   5742 H H    . GLU A 1 344 ? -2.274  -17.980 -15.799 1.000 9.139  0 359  GLU A H    1 c 
ATOM   5743 H HA   . GLU A 1 344 ? -3.868  -19.439 -14.178 1.000 9.583  0 359  GLU A HA   1 c 
ATOM   5744 H HB2  . GLU A 1 344 ? -4.116  -16.739 -15.023 1.000 11.201 0 359  GLU A HB2  1 c 
ATOM   5745 H HB3  . GLU A 1 344 ? -5.150  -17.375 -14.003 1.000 11.266 0 359  GLU A HB3  1 c 
ATOM   5746 H HG2  . GLU A 1 344 ? -2.352  -17.107 -13.547 1.000 13.796 0 359  GLU A HG2  1 c 
ATOM   5747 H HG3  . GLU A 1 344 ? -3.459  -16.273 -12.805 1.000 13.769 0 359  GLU A HG3  1 c 
ATOM   5748 N N    . ILE A 1 345 ? -5.176  -18.885 -17.088 1.000 8.452  0 360  ILE A N    1 ? 
ATOM   5749 C CA   . ILE A 1 345 ? -6.276  -19.338 -17.933 1.000 8.876  0 360  ILE A CA   1 ? 
ATOM   5750 C C    . ILE A 1 345 ? -6.072  -20.803 -18.318 1.000 8.849  0 360  ILE A C    1 ? 
ATOM   5751 O O    . ILE A 1 345 ? -7.058  -21.561 -18.471 1.000 8.649  0 360  ILE A O    1 ? 
ATOM   5752 C CB   . ILE A 1 345 ? -6.514  -18.407 -19.137 1.000 9.695  0 360  ILE A CB   1 ? 
ATOM   5753 C CG1  . ILE A 1 345 ? -8.000  -18.508 -19.602 1.000 11.732 0 360  ILE A CG1  1 ? 
ATOM   5754 C CG2  . ILE A 1 345 ? -5.533  -18.625 -20.303 1.000 9.553  0 360  ILE A CG2  1 ? 
ATOM   5755 C CD1  . ILE A 1 345 ? -8.986  -18.091 -18.556 1.000 13.223 0 360  ILE A CD1  1 ? 
ATOM   5756 H H    . ILE A 1 345 ? -4.544  -18.319 -17.428 1.000 8.732  0 360  ILE A H    1 c 
ATOM   5757 H HA   . ILE A 1 345 ? -7.081  -19.301 -17.385 1.000 8.994  0 360  ILE A HA   1 c 
ATOM   5758 H HB   . ILE A 1 345 ? -6.380  -17.495 -18.819 1.000 9.819  0 360  ILE A HB   1 c 
ATOM   5759 H HG12 . ILE A 1 345 ? -8.122  -17.945 -20.393 1.000 11.565 0 360  ILE A HG12 1 c 
ATOM   5760 H HG13 . ILE A 1 345 ? -8.187  -19.434 -19.860 1.000 11.565 0 360  ILE A HG13 1 c 
ATOM   5761 H HG21 . ILE A 1 345 ? -5.672  -17.938 -20.977 1.000 9.592  0 360  ILE A HG21 1 c 
ATOM   5762 H HG22 . ILE A 1 345 ? -5.685  -19.499 -20.700 1.000 9.589  0 360  ILE A HG22 1 c 
ATOM   5763 H HG23 . ILE A 1 345 ? -4.621  -18.573 -19.975 1.000 9.589  0 360  ILE A HG23 1 c 
ATOM   5764 H HD11 . ILE A 1 345 ? -9.110  -18.807 -17.904 1.000 12.683 0 360  ILE A HD11 1 c 
ATOM   5765 H HD12 . ILE A 1 345 ? -9.842  -17.887 -18.978 1.000 12.724 0 360  ILE A HD12 1 c 
ATOM   5766 H HD13 . ILE A 1 345 ? -8.650  -17.294 -18.103 1.000 12.675 0 360  ILE A HD13 1 c 
ATOM   5767 N N    . TYR A 1 346 ? -4.811  -21.259 -18.501 1.000 7.462  0 361  TYR A N    1 ? 
ATOM   5768 C CA   . TYR A 1 346 ? -4.547  -22.688 -18.665 1.000 7.622  0 361  TYR A CA   1 ? 
ATOM   5769 C C    . TYR A 1 346 ? -5.121  -23.464 -17.488 1.000 8.250  0 361  TYR A C    1 ? 
ATOM   5770 O O    . TYR A 1 346 ? -5.743  -24.505 -17.706 1.000 8.146  0 361  TYR A O    1 ? 
ATOM   5771 C CB   . TYR A 1 346 ? -3.048  -22.934 -18.860 1.000 8.053  0 361  TYR A CB   1 ? 
ATOM   5772 C CG   . TYR A 1 346 ? -2.663  -24.396 -18.930 1.000 8.253  0 361  TYR A CG   1 ? 
ATOM   5773 C CD1  . TYR A 1 346 ? -2.426  -25.110 -17.772 1.000 9.658  0 361  TYR A CD1  1 ? 
ATOM   5774 C CD2  . TYR A 1 346 ? -2.587  -25.078 -20.136 1.000 9.539  0 361  TYR A CD2  1 ? 
ATOM   5775 C CE1  . TYR A 1 346 ? -2.142  -26.471 -17.808 1.000 10.906 0 361  TYR A CE1  1 ? 
ATOM   5776 C CE2  . TYR A 1 346 ? -2.320  -26.447 -20.176 1.000 10.194 0 361  TYR A CE2  1 ? 
ATOM   5777 C CZ   . TYR A 1 346 ? -2.046  -27.120 -19.020 1.000 9.490  0 361  TYR A CZ   1 ? 
ATOM   5778 O OH   . TYR A 1 346 ? -1.803  -28.471 -19.059 1.000 10.384 0 361  TYR A OH   1 ? 
ATOM   5779 H H    . TYR A 1 346 ? -4.113  -20.670 -18.531 1.000 7.815  0 361  TYR A H    1 c 
ATOM   5780 H HA   . TYR A 1 346 ? -5.014  -22.990 -19.487 1.000 7.801  0 361  TYR A HA   1 c 
ATOM   5781 H HB2  . TYR A 1 346 ? -2.766  -22.491 -19.690 1.000 8.016  0 361  TYR A HB2  1 c 
ATOM   5782 H HB3  . TYR A 1 346 ? -2.563  -22.513 -18.115 1.000 8.007  0 361  TYR A HB3  1 c 
ATOM   5783 H HD1  . TYR A 1 346 ? -2.483  -24.672 -16.937 1.000 9.574  0 361  TYR A HD1  1 c 
ATOM   5784 H HD2  . TYR A 1 346 ? -2.771  -24.620 -20.940 1.000 9.372  0 361  TYR A HD2  1 c 
ATOM   5785 H HE1  . TYR A 1 346 ? -1.977  -26.940 -17.009 1.000 10.320 0 361  TYR A HE1  1 c 
ATOM   5786 H HE2  . TYR A 1 346 ? -2.263  -26.891 -21.003 1.000 9.872  0 361  TYR A HE2  1 c 
ATOM   5787 H HH   . TYR A 1 346 ? -2.545  -28.903 -19.055 0.000 10.390 0 361  TYR A HH   1 c 
ATOM   5788 N N    . LYS A 1 347 ? -4.866  -22.996 -16.267 1.000 8.012  0 362  LYS A N    1 ? 
ATOM   5789 C CA   . LYS A 1 347 ? -5.345  -23.693 -15.094 1.000 9.410  0 362  LYS A CA   1 ? 
ATOM   5790 C C    . LYS A 1 347 ? -6.859  -23.830 -15.115 1.000 8.911  0 362  LYS A C    1 ? 
ATOM   5791 O O    . LYS A 1 347 ? -7.372  -24.893 -14.763 1.000 9.526  0 362  LYS A O    1 ? 
ATOM   5792 C CB   . LYS A 1 347 ? -4.815  -23.011 -13.822 1.000 11.388 0 362  LYS A CB   1 ? 
ATOM   5793 C CG   . LYS A 1 347 ? -3.349  -23.268 -13.557 1.000 15.837 0 362  LYS A CG   1 ? 
ATOM   5794 C CD   . LYS A 1 347 ? -2.766  -22.363 -12.461 1.000 22.042 0 362  LYS A CD   1 ? 
ATOM   5795 C CE   . LYS A 1 347 ? -3.421  -22.446 -11.137 1.000 28.068 0 362  LYS A CE   1 ? 
ATOM   5796 N NZ   . LYS A 1 347 ? -2.756  -21.433 -10.295 1.000 31.325 0 362  LYS A NZ   1 ? 
ATOM   5797 H H    . LYS A 1 347 ? -4.379  -22.229 -16.163 1.000 8.396  0 362  LYS A H    1 c 
ATOM   5798 H HA   . LYS A 1 347 ? -4.962  -24.607 -15.114 1.000 9.340  0 362  LYS A HA   1 c 
ATOM   5799 H HB2  . LYS A 1 347 ? -4.955  -22.043 -13.896 1.000 11.760 0 362  LYS A HB2  1 c 
ATOM   5800 H HB3  . LYS A 1 347 ? -5.332  -23.331 -13.052 1.000 11.877 0 362  LYS A HB3  1 c 
ATOM   5801 H HG2  . LYS A 1 347 ? -3.238  -24.206 -13.291 1.000 15.801 0 362  LYS A HG2  1 c 
ATOM   5802 H HG3  . LYS A 1 347 ? -2.849  -23.128 -14.390 1.000 15.765 0 362  LYS A HG3  1 c 
ATOM   5803 H HD2  . LYS A 1 347 ? -1.815  -22.585 -12.355 1.000 21.715 0 362  LYS A HD2  1 c 
ATOM   5804 H HD3  . LYS A 1 347 ? -2.811  -21.434 -12.776 1.000 21.753 0 362  LYS A HD3  1 c 
ATOM   5805 H HE2  . LYS A 1 347 ? -4.372  -22.245 -11.203 1.000 26.949 0 362  LYS A HE2  1 c 
ATOM   5806 H HE3  . LYS A 1 347 ? -3.303  -23.331 -10.748 1.000 27.178 0 362  LYS A HE3  1 c 
ATOM   5807 H HZ1  . LYS A 1 347 ? -2.906  -20.605 -10.627 1.000 30.043 0 362  LYS A HZ1  1 c 
ATOM   5808 H HZ2  . LYS A 1 347 ? -1.863  -21.587 -10.267 1.000 30.104 0 362  LYS A HZ2  1 c 
ATOM   5809 H HZ3  . LYS A 1 347 ? -3.087  -21.476 -9.453  1.000 30.204 0 362  LYS A HZ3  1 c 
ATOM   5810 N N    . GLU A 1 348 ? -7.575  -22.790 -15.510 1.000 8.677  0 363  GLU A N    1 ? 
ATOM   5811 C CA   . GLU A 1 348 ? -9.023  -22.858 -15.539 1.000 8.644  0 363  GLU A CA   1 ? 
ATOM   5812 C C    . GLU A 1 348 ? -9.507  -23.840 -16.597 1.000 8.391  0 363  GLU A C    1 ? 
ATOM   5813 O O    . GLU A 1 348 ? -10.397 -24.661 -16.341 1.000 9.216  0 363  GLU A O    1 ? 
ATOM   5814 C CB   . GLU A 1 348 ? -9.704  -21.498 -15.754 1.000 11.182 0 363  GLU A CB   1 ? 
ATOM   5815 C CG   . GLU A 1 348 ? -9.354  -20.462 -14.686 1.000 13.840 0 363  GLU A CG   1 ? 
ATOM   5816 C CD   . GLU A 1 348 ? -9.708  -20.803 -13.249 1.000 15.692 0 363  GLU A CD   1 ? 
ATOM   5817 O OE1  . GLU A 1 348 ? -10.446 -21.758 -12.969 1.000 13.605 0 363  GLU A OE1  1 ? 
ATOM   5818 O OE2  . GLU A 1 348 ? -9.091  -20.198 -12.314 1.000 21.157 0 363  GLU A OE2  1 ? 
ATOM   5819 H H    . GLU A 1 348 ? -7.159  -22.017 -15.766 1.000 8.789  0 363  GLU A H    1 c 
ATOM   5820 H HA   . GLU A 1 348 ? -9.322  -23.200 -14.659 1.000 9.068  0 363  GLU A HA   1 c 
ATOM   5821 H HB2  . GLU A 1 348 ? -9.445  -21.150 -16.633 1.000 11.062 0 363  GLU A HB2  1 c 
ATOM   5822 H HB3  . GLU A 1 348 ? -10.674 -21.631 -15.760 1.000 11.021 0 363  GLU A HB3  1 c 
ATOM   5823 H HG2  . GLU A 1 348 ? -8.391  -20.289 -14.726 1.000 13.473 0 363  GLU A HG2  1 c 
ATOM   5824 H HG3  . GLU A 1 348 ? -9.801  -19.619 -14.915 1.000 13.551 0 363  GLU A HG3  1 c 
ATOM   5825 N N    . PHE A 1 349 ? -8.947  -23.783 -17.821 1.000 8.103  0 364  PHE A N    1 ? 
ATOM   5826 C CA   . PHE A 1 349 ? -9.347  -24.757 -18.837 1.000 7.275  0 364  PHE A CA   1 ? 
ATOM   5827 C C    . PHE A 1 349 ? -9.015  -26.190 -18.401 1.000 7.236  0 364  PHE A C    1 ? 
ATOM   5828 O O    . PHE A 1 349 ? -9.806  -27.099 -18.636 1.000 7.748  0 364  PHE A O    1 ? 
ATOM   5829 C CB   . PHE A 1 349 ? -8.662  -24.457 -20.183 1.000 8.152  0 364  PHE A CB   1 ? 
ATOM   5830 C CG   . PHE A 1 349 ? -9.399  -23.464 -21.064 1.000 7.675  0 364  PHE A CG   1 ? 
ATOM   5831 C CD1  . PHE A 1 349 ? -10.476 -23.851 -21.814 1.000 8.733  0 364  PHE A CD1  1 ? 
ATOM   5832 C CD2  . PHE A 1 349 ? -9.036  -22.126 -21.103 1.000 8.913  0 364  PHE A CD2  1 ? 
ATOM   5833 C CE1  . PHE A 1 349 ? -11.147 -22.938 -22.605 1.000 9.333  0 364  PHE A CE1  1 ? 
ATOM   5834 C CE2  . PHE A 1 349 ? -9.715  -21.223 -21.907 1.000 9.275  0 364  PHE A CE2  1 ? 
ATOM   5835 C CZ   . PHE A 1 349 ? -10.758 -21.624 -22.649 1.000 9.105  0 364  PHE A CZ   1 ? 
ATOM   5836 H H    . PHE A 1 349 ? -8.327  -23.142 -18.023 1.000 7.986  0 364  PHE A H    1 c 
ATOM   5837 H HA   . PHE A 1 349 ? -10.330 -24.688 -18.964 1.000 7.589  0 364  PHE A HA   1 c 
ATOM   5838 H HB2  . PHE A 1 349 ? -7.760  -24.112 -20.003 1.000 7.837  0 364  PHE A HB2  1 c 
ATOM   5839 H HB3  . PHE A 1 349 ? -8.563  -25.302 -20.676 1.000 7.833  0 364  PHE A HB3  1 c 
ATOM   5840 H HD1  . PHE A 1 349 ? -10.753 -24.753 -21.802 1.000 8.612  0 364  PHE A HD1  1 c 
ATOM   5841 H HD2  . PHE A 1 349 ? -8.298  -21.832 -20.595 1.000 8.693  0 364  PHE A HD2  1 c 
ATOM   5842 H HE1  . PHE A 1 349 ? -11.881 -23.225 -23.126 1.000 9.123  0 364  PHE A HE1  1 c 
ATOM   5843 H HE2  . PHE A 1 349 ? -9.443  -20.319 -21.929 1.000 9.136  0 364  PHE A HE2  1 c 
ATOM   5844 H HZ   . PHE A 1 349 ? -11.225 -21.006 -23.189 1.000 9.184  0 364  PHE A HZ   1 c 
ATOM   5845 N N    . PHE A 1 350 ? -7.857  -26.383 -17.759 1.000 7.412  0 365  PHE A N    1 ? 
ATOM   5846 C CA   . PHE A 1 350 ? -7.461  -27.704 -17.303 1.000 7.548  0 365  PHE A CA   1 ? 
ATOM   5847 C C    . PHE A 1 350 ? -8.472  -28.254 -16.286 1.000 8.173  0 365  PHE A C    1 ? 
ATOM   5848 O O    . PHE A 1 350 ? -8.884  -29.439 -16.356 1.000 8.224  0 365  PHE A O    1 ? 
ATOM   5849 C CB   . PHE A 1 350 ? -6.060  -27.644 -16.669 1.000 7.812  0 365  PHE A CB   1 ? 
ATOM   5850 C CG   . PHE A 1 350 ? -5.492  -29.009 -16.320 1.000 8.736  0 365  PHE A CG   1 ? 
ATOM   5851 C CD1  . PHE A 1 350 ? -5.867  -29.630 -15.147 1.000 9.226  0 365  PHE A CD1  1 ? 
ATOM   5852 C CD2  . PHE A 1 350 ? -4.604  -29.626 -17.186 1.000 9.387  0 365  PHE A CD2  1 ? 
ATOM   5853 C CE1  . PHE A 1 350 ? -5.425  -30.930 -14.858 1.000 10.435 0 365  PHE A CE1  1 ? 
ATOM   5854 C CE2  . PHE A 1 350 ? -4.117  -30.900 -16.886 1.000 10.520 0 365  PHE A CE2  1 ? 
ATOM   5855 C CZ   . PHE A 1 350 ? -4.533  -31.536 -15.726 1.000 10.388 0 365  PHE A CZ   1 ? 
ATOM   5856 H H    . PHE A 1 350 ? -7.298  -25.676 -17.607 1.000 7.407  0 365  PHE A H    1 c 
ATOM   5857 H HA   . PHE A 1 350 ? -7.431  -28.314 -18.087 1.000 7.678  0 365  PHE A HA   1 c 
ATOM   5858 H HB2  . PHE A 1 350 ? -5.451  -27.196 -17.297 1.000 7.969  0 365  PHE A HB2  1 c 
ATOM   5859 H HB3  . PHE A 1 350 ? -6.109  -27.100 -15.852 1.000 7.956  0 365  PHE A HB3  1 c 
ATOM   5860 H HD1  . PHE A 1 350 ? -6.498  -29.215 -14.581 1.000 9.370  0 365  PHE A HD1  1 c 
ATOM   5861 H HD2  . PHE A 1 350 ? -4.347  -29.195 -17.985 1.000 9.467  0 365  PHE A HD2  1 c 
ATOM   5862 H HE1  . PHE A 1 350 ? -5.676  -31.355 -14.053 1.000 10.118 0 365  PHE A HE1  1 c 
ATOM   5863 H HE2  . PHE A 1 350 ? -3.516  -31.329 -17.475 1.000 10.197 0 365  PHE A HE2  1 c 
ATOM   5864 H HZ   . PHE A 1 350 ? -4.189  -32.388 -15.516 1.000 10.400 0 365  PHE A HZ   1 c 
ATOM   5865 N N    A GLU A 1 351 ? -8.858  -27.423 -15.323 0.500 8.336  0 366  GLU A N    1 ? 
ATOM   5866 N N    B GLU A 1 351 ? -8.848  -27.439 -15.305 0.500 8.686  0 366  GLU A N    1 ? 
ATOM   5867 C CA   A GLU A 1 351 ? -9.776  -27.838 -14.280 0.500 8.474  0 366  GLU A CA   1 ? 
ATOM   5868 C CA   B GLU A 1 351 ? -9.787  -27.877 -14.291 0.500 9.096  0 366  GLU A CA   1 ? 
ATOM   5869 C C    A GLU A 1 351 ? -11.173 -28.106 -14.847 0.500 8.157  0 366  GLU A C    1 ? 
ATOM   5870 C C    B GLU A 1 351 ? -11.158 -28.166 -14.898 0.500 8.494  0 366  GLU A C    1 ? 
ATOM   5871 O O    A GLU A 1 351 ? -11.860 -29.033 -14.416 0.500 8.472  0 366  GLU A O    1 ? 
ATOM   5872 O O    B GLU A 1 351 ? -11.784 -29.180 -14.557 0.500 8.762  0 366  GLU A O    1 ? 
ATOM   5873 C CB   A GLU A 1 351 ? -9.800  -26.804 -13.160 0.500 9.535  0 366  GLU A CB   1 ? 
ATOM   5874 C CB   B GLU A 1 351 ? -9.886  -26.877 -13.148 0.500 10.707 0 366  GLU A CB   1 ? 
ATOM   5875 C CG   A GLU A 1 351 ? -10.588 -27.273 -11.944 0.500 11.196 0 366  GLU A CG   1 ? 
ATOM   5876 C CG   B GLU A 1 351 ? -8.623  -26.871 -12.296 0.500 13.059 0 366  GLU A CG   1 ? 
ATOM   5877 C CD   A GLU A 1 351 ? -10.587 -26.352 -10.748 0.500 13.101 0 366  GLU A CD   1 ? 
ATOM   5878 C CD   B GLU A 1 351 ? -8.189  -28.244 -11.773 0.500 17.200 0 366  GLU A CD   1 ? 
ATOM   5879 O OE1  A GLU A 1 351 ? -9.722  -25.465 -10.679 0.500 12.223 0 366  GLU A OE1  1 ? 
ATOM   5880 O OE1  B GLU A 1 351 ? -9.094  -28.971 -11.282 0.500 21.730 0 366  GLU A OE1  1 ? 
ATOM   5881 O OE2  A GLU A 1 351 ? -11.481 -26.640 -9.902  0.500 17.112 0 366  GLU A OE2  1 ? 
ATOM   5882 O OE2  B GLU A 1 351 ? -6.975  -28.634 -11.862 0.500 18.424 0 366  GLU A OE2  1 ? 
ATOM   5883 H H    A GLU A 1 351 ? -8.536  -26.567 -15.310 0.500 8.316  0 366  GLU A H    1 c 
ATOM   5884 H H    B GLU A 1 351 ? -8.510  -26.591 -15.261 0.500 8.634  0 366  GLU A H    1 c 
ATOM   5885 H HA   A GLU A 1 351 ? -9.435  -28.685 -13.895 0.500 8.569  0 366  GLU A HA   1 c 
ATOM   5886 H HA   B GLU A 1 351 ? -9.442  -28.723 -13.907 0.500 9.166  0 366  GLU A HA   1 c 
ATOM   5887 H HB2  A GLU A 1 351 ? -8.879  -26.606 -12.891 0.500 9.627  0 366  GLU A HB2  1 c 
ATOM   5888 H HB2  B GLU A 1 351 ? -10.036 -25.983 -13.519 0.500 10.791 0 366  GLU A HB2  1 c 
ATOM   5889 H HB3  A GLU A 1 351 ? -10.197 -25.976 -13.502 0.500 9.627  0 366  GLU A HB3  1 c 
ATOM   5890 H HB3  B GLU A 1 351 ? -10.658 -27.106 -12.590 0.500 10.791 0 366  GLU A HB3  1 c 
ATOM   5891 H HG2  A GLU A 1 351 ? -11.519 -27.420 -12.213 0.500 11.195 0 366  GLU A HG2  1 c 
ATOM   5892 H HG2  B GLU A 1 351 ? -7.892  -26.495 -12.823 0.500 13.351 0 366  GLU A HG2  1 c 
ATOM   5893 H HG3  A GLU A 1 351 ? -10.233 -28.141 -11.658 0.500 11.195 0 366  GLU A HG3  1 c 
ATOM   5894 H HG3  B GLU A 1 351 ? -8.764  -26.278 -11.527 0.500 13.303 0 366  GLU A HG3  1 c 
ATOM   5895 N N    . VAL A 1 352 ? -11.617 -27.308 -15.825 1.000 8.311  0 367  VAL A N    1 ? 
ATOM   5896 C CA   . VAL A 1 352 ? -12.903 -27.579 -16.449 1.000 8.704  0 367  VAL A CA   1 ? 
ATOM   5897 C C    . VAL A 1 352 ? -12.856 -28.917 -17.202 1.000 8.582  0 367  VAL A C    1 ? 
ATOM   5898 O O    . VAL A 1 352 ? -13.736 -29.748 -17.062 1.000 8.556  0 367  VAL A O    1 ? 
ATOM   5899 C CB   . VAL A 1 352 ? -13.324 -26.438 -17.379 1.000 8.389  0 367  VAL A CB   1 ? 
ATOM   5900 C CG1  . VAL A 1 352 ? -14.521 -26.797 -18.248 1.000 7.942  0 367  VAL A CG1  1 ? 
ATOM   5901 C CG2  . VAL A 1 352 ? -13.622 -25.148 -16.606 1.000 8.368  0 367  VAL A CG2  1 ? 
ATOM   5902 H H    . VAL A 1 352 ? -11.127 -26.579 -16.078 1.000 8.390  0 367  VAL A H    1 c 
ATOM   5903 H HA   . VAL A 1 352 ? -13.572 -27.651 -15.742 1.000 8.551  0 367  VAL A HA   1 c 
ATOM   5904 H HB   . VAL A 1 352 ? -12.563 -26.258 -17.979 1.000 8.357  0 367  VAL A HB   1 c 
ATOM   5905 H HG11 . VAL A 1 352 ? -15.211 -27.207 -17.699 1.000 8.073  0 367  VAL A HG11 1 c 
ATOM   5906 H HG12 . VAL A 1 352 ? -14.246 -27.421 -18.941 1.000 8.075  0 367  VAL A HG12 1 c 
ATOM   5907 H HG13 . VAL A 1 352 ? -14.875 -25.992 -18.663 1.000 8.076  0 367  VAL A HG13 1 c 
ATOM   5908 H HG21 . VAL A 1 352 ? -13.778 -24.422 -17.233 1.000 8.373  0 367  VAL A HG21 1 c 
ATOM   5909 H HG22 . VAL A 1 352 ? -12.867 -24.927 -16.037 1.000 8.379  0 367  VAL A HG22 1 c 
ATOM   5910 H HG23 . VAL A 1 352 ? -14.413 -25.275 -16.056 1.000 8.375  0 367  VAL A HG23 1 c 
ATOM   5911 N N    . ALA A 1 353 ? -11.824 -29.129 -18.024 1.000 7.652  0 368  ALA A N    1 ? 
ATOM   5912 C CA   . ALA A 1 353 ? -11.730 -30.344 -18.827 1.000 7.900  0 368  ALA A CA   1 ? 
ATOM   5913 C C    . ALA A 1 353 ? -11.548 -31.588 -17.990 1.000 8.846  0 368  ALA A C    1 ? 
ATOM   5914 O O    . ALA A 1 353 ? -12.073 -32.646 -18.314 1.000 8.206  0 368  ALA A O    1 ? 
ATOM   5915 C CB   . ALA A 1 353 ? -10.574 -30.233 -19.804 1.000 7.869  0 368  ALA A CB   1 ? 
ATOM   5916 H H    . ALA A 1 353 ? -11.162 -28.502 -18.090 1.000 7.928  0 368  ALA A H    1 c 
ATOM   5917 H HA   . ALA A 1 353 ? -12.578 -30.440 -19.342 1.000 8.018  0 368  ALA A HA   1 c 
ATOM   5918 H HB1  . ALA A 1 353 ? -10.702 -29.458 -20.376 1.000 7.882  0 368  ALA A HB1  1 c 
ATOM   5919 H HB2  . ALA A 1 353 ? -9.740  -30.135 -19.314 1.000 7.880  0 368  ALA A HB2  1 c 
ATOM   5920 H HB3  . ALA A 1 353 ? -10.531 -31.034 -20.353 1.000 7.884  0 368  ALA A HB3  1 c 
ATOM   5921 N N    . ASN A 1 354 ? -10.710 -31.482 -16.945 1.000 8.487  0 369  ASN A N    1 ? 
ATOM   5922 C CA   . ASN A 1 354 ? -10.165 -32.669 -16.314 1.000 7.932  0 369  ASN A CA   1 ? 
ATOM   5923 C C    . ASN A 1 354 ? -10.767 -32.935 -14.938 1.000 8.465  0 369  ASN A C    1 ? 
ATOM   5924 O O    . ASN A 1 354 ? -10.375 -33.943 -14.323 1.000 11.234 0 369  ASN A O    1 ? 
ATOM   5925 C CB   . ASN A 1 354 ? -8.639  -32.592 -16.332 1.000 8.635  0 369  ASN A CB   1 ? 
ATOM   5926 C CG   . ASN A 1 354 ? -8.126  -32.481 -17.735 1.000 9.322  0 369  ASN A CG   1 ? 
ATOM   5927 O OD1  . ASN A 1 354 ? -8.612  -33.228 -18.585 1.000 10.681 0 369  ASN A OD1  1 ? 
ATOM   5928 N ND2  . ASN A 1 354 ? -7.147  -31.640 -18.008 1.000 9.338  0 369  ASN A ND2  1 ? 
ATOM   5929 H H    . ASN A 1 354 ? -10.469 -30.659 -16.629 1.000 8.437  0 369  ASN A H    1 c 
ATOM   5930 H HA   . ASN A 1 354 ? -10.409 -33.438 -16.876 1.000 8.284  0 369  ASN A HA   1 c 
ATOM   5931 H HB2  . ASN A 1 354 ? -8.345  -31.816 -15.815 1.000 8.629  0 369  ASN A HB2  1 c 
ATOM   5932 H HB3  . ASN A 1 354 ? -8.269  -33.395 -15.914 1.000 8.646  0 369  ASN A HB3  1 c 
ATOM   5933 H HD21 . ASN A 1 354 ? -7.117  -30.854 -17.598 1.000 9.323  0 369  ASN A HD21 1 c 
ATOM   5934 H HD22 . ASN A 1 354 ? -6.525  -31.861 -18.603 1.000 9.327  0 369  ASN A HD22 1 c 
ATOM   5935 N N    . ASP A 1 355 ? -11.629 -32.066 -14.452 1.000 8.943  0 370  ASP A N    1 ? 
ATOM   5936 C CA   . ASP A 1 355 ? -12.264 -32.257 -13.159 1.000 10.133 0 370  ASP A CA   1 ? 
ATOM   5937 C C    . ASP A 1 355 ? -13.751 -31.940 -13.232 1.000 9.879  0 370  ASP A C    1 ? 
ATOM   5938 O O    . ASP A 1 355 ? -14.571 -32.808 -12.947 1.000 10.337 0 370  ASP A O    1 ? 
ATOM   5939 C CB   . ASP A 1 355 ? -11.568 -31.471 -12.068 1.000 11.950 0 370  ASP A CB   1 ? 
ATOM   5940 C CG   . ASP A 1 355 ? -12.199 -31.748 -10.704 1.000 18.833 0 370  ASP A CG   1 ? 
ATOM   5941 O OD1  . ASP A 1 355 ? -12.132 -32.928 -10.267 1.000 26.057 0 370  ASP A OD1  1 ? 
ATOM   5942 O OD2  . ASP A 1 355 ? -12.814 -30.831 -10.185 1.000 30.596 0 370  ASP A OD2  1 ? 
ATOM   5943 H H    . ASP A 1 355 ? -11.834 -31.318 -14.934 1.000 9.060  0 370  ASP A H    1 c 
ATOM   5944 H HA   . ASP A 1 355 ? -12.174 -33.206 -12.915 1.000 10.240 0 370  ASP A HA   1 c 
ATOM   5945 H HB2  . ASP A 1 355 ? -10.621 -31.722 -12.036 1.000 12.788 0 370  ASP A HB2  1 c 
ATOM   5946 H HB3  . ASP A 1 355 ? -11.630 -30.512 -12.257 1.000 12.809 0 370  ASP A HB3  1 c 
ATOM   5947 N N    . VAL A 1 356 ? -14.122 -30.733 -13.662 1.000 8.376  0 371  VAL A N    1 ? 
ATOM   5948 C CA   . VAL A 1 356 ? -15.510 -30.294 -13.600 1.000 8.648  0 371  VAL A CA   1 ? 
ATOM   5949 C C    . VAL A 1 356 ? -16.385 -31.050 -14.594 1.000 8.705  0 371  VAL A C    1 ? 
ATOM   5950 O O    . VAL A 1 356 ? -17.453 -31.573 -14.196 1.000 9.823  0 371  VAL A O    1 ? 
ATOM   5951 C CB   . VAL A 1 356 ? -15.606 -28.766 -13.786 1.000 9.460  0 371  VAL A CB   1 ? 
ATOM   5952 C CG1  . VAL A 1 356 ? -17.041 -28.273 -13.676 1.000 10.308 0 371  VAL A CG1  1 ? 
ATOM   5953 C CG2  . VAL A 1 356 ? -14.779 -28.038 -12.748 1.000 10.775 0 371  VAL A CG2  1 ? 
ATOM   5954 H H    . VAL A 1 356 ? -13.494 -30.168 -14.011 1.000 8.813  0 371  VAL A H    1 c 
ATOM   5955 H HA   . VAL A 1 356 ? -15.840 -30.499 -12.703 1.000 8.767  0 371  VAL A HA   1 c 
ATOM   5956 H HB   . VAL A 1 356 ? -15.262 -28.550 -14.683 1.000 9.677  0 371  VAL A HB   1 c 
ATOM   5957 H HG11 . VAL A 1 356 ? -17.436 -28.604 -12.852 1.000 10.050 0 371  VAL A HG11 1 c 
ATOM   5958 H HG12 . VAL A 1 356 ? -17.557 -28.597 -14.434 1.000 10.044 0 371  VAL A HG12 1 c 
ATOM   5959 H HG13 . VAL A 1 356 ? -17.052 -27.301 -13.671 1.000 10.055 0 371  VAL A HG13 1 c 
ATOM   5960 H HG21 . VAL A 1 356 ? -14.872 -27.080 -12.874 1.000 10.386 0 371  VAL A HG21 1 c 
ATOM   5961 H HG22 . VAL A 1 356 ? -13.844 -28.284 -12.842 1.000 10.337 0 371  VAL A HG22 1 c 
ATOM   5962 H HG23 . VAL A 1 356 ? -15.088 -28.279 -11.859 1.000 10.365 0 371  VAL A HG23 1 c 
ATOM   5963 N N    . ILE A 1 357 ? -16.006 -31.087 -15.861 1.000 7.685  0 372  ILE A N    1 ? 
ATOM   5964 C CA   . ILE A 1 357 ? -16.782 -31.806 -16.851 1.000 8.085  0 372  ILE A CA   1 ? 
ATOM   5965 C C    . ILE A 1 357 ? -16.882 -33.272 -16.452 1.000 8.537  0 372  ILE A C    1 ? 
ATOM   5966 O O    . ILE A 1 357 ? -17.988 -33.811 -16.431 1.000 8.874  0 372  ILE A O    1 ? 
ATOM   5967 C CB   . ILE A 1 357 ? -16.300 -31.576 -18.287 1.000 7.663  0 372  ILE A CB   1 ? 
ATOM   5968 C CG1  . ILE A 1 357 ? -16.704 -30.185 -18.762 1.000 8.615  0 372  ILE A CG1  1 ? 
ATOM   5969 C CG2  . ILE A 1 357 ? -16.816 -32.649 -19.239 1.000 8.373  0 372  ILE A CG2  1 ? 
ATOM   5970 C CD1  . ILE A 1 357 ? -16.036 -29.758 -20.054 1.000 8.621  0 372  ILE A CD1  1 ? 
ATOM   5971 H H    . ILE A 1 357 ? -15.245 -30.652 -16.121 1.000 8.012  0 372  ILE A H    1 c 
ATOM   5972 H HA   . ILE A 1 357 ? -17.689 -31.444 -16.806 1.000 8.028  0 372  ILE A HA   1 c 
ATOM   5973 H HB   . ILE A 1 357 ? -15.324 -31.617 -18.287 1.000 8.051  0 372  ILE A HB   1 c 
ATOM   5974 H HG12 . ILE A 1 357 ? -17.674 -30.165 -18.888 1.000 8.389  0 372  ILE A HG12 1 c 
ATOM   5975 H HG13 . ILE A 1 357 ? -16.479 -29.537 -18.063 1.000 8.384  0 372  ILE A HG13 1 c 
ATOM   5976 H HG21 . ILE A 1 357 ? -16.589 -32.412 -20.154 1.000 8.164  0 372  ILE A HG21 1 c 
ATOM   5977 H HG22 . ILE A 1 357 ? -17.782 -32.722 -19.156 1.000 8.161  0 372  ILE A HG22 1 c 
ATOM   5978 H HG23 . ILE A 1 357 ? -16.408 -33.504 -19.021 1.000 8.161  0 372  ILE A HG23 1 c 
ATOM   5979 H HD11 . ILE A 1 357 ? -15.074 -29.908 -19.990 1.000 8.618  0 372  ILE A HD11 1 c 
ATOM   5980 H HD12 . ILE A 1 357 ? -16.207 -28.810 -20.209 1.000 8.618  0 372  ILE A HD12 1 c 
ATOM   5981 H HD13 . ILE A 1 357 ? -16.395 -30.276 -20.800 1.000 8.615  0 372  ILE A HD13 1 c 
ATOM   5982 N N    . PRO A 1 358 ? -15.794 -33.963 -16.077 1.000 9.033  0 373  PRO A N    1 ? 
ATOM   5983 C CA   . PRO A 1 358 ? -15.944 -35.360 -15.691 1.000 8.828  0 373  PRO A CA   1 ? 
ATOM   5984 C C    . PRO A 1 358 ? -16.960 -35.569 -14.569 1.000 10.380 0 373  PRO A C    1 ? 
ATOM   5985 O O    . PRO A 1 358 ? -17.738 -36.543 -14.604 1.000 10.420 0 373  PRO A O    1 ? 
ATOM   5986 C CB   . PRO A 1 358 ? -14.520 -35.790 -15.326 1.000 9.681  0 373  PRO A CB   1 ? 
ATOM   5987 C CG   . PRO A 1 358 ? -13.674 -34.937 -16.244 1.000 9.241  0 373  PRO A CG   1 ? 
ATOM   5988 C CD   . PRO A 1 358 ? -14.370 -33.594 -16.286 1.000 9.143  0 373  PRO A CD   1 ? 
ATOM   5989 H HA   . PRO A 1 358 ? -16.236 -35.867 -16.489 1.000 9.298  0 373  PRO A HA   1 c 
ATOM   5990 H HB2  . PRO A 1 358 ? -14.322 -35.598 -14.379 1.000 9.390  0 373  PRO A HB2  1 c 
ATOM   5991 H HB3  . PRO A 1 358 ? -14.381 -36.750 -15.504 1.000 9.386  0 373  PRO A HB3  1 c 
ATOM   5992 H HG2  . PRO A 1 358 ? -12.764 -34.846 -15.893 1.000 9.312  0 373  PRO A HG2  1 c 
ATOM   5993 H HG3  . PRO A 1 358 ? -13.628 -35.331 -17.140 1.000 9.315  0 373  PRO A HG3  1 c 
ATOM   5994 H HD2  . PRO A 1 358 ? -14.046 -33.004 -15.573 1.000 9.144  0 373  PRO A HD2  1 c 
ATOM   5995 H HD3  . PRO A 1 358 ? -14.241 -33.157 -17.154 1.000 9.114  0 373  PRO A HD3  1 c 
ATOM   5996 N N    . ASN A 1 359 ? -16.914 -34.712 -13.545 1.000 10.086 0 374  ASN A N    1 ? 
ATOM   5997 C CA   . ASN A 1 359 ? -17.837 -34.887 -12.424 1.000 11.351 0 374  ASN A CA   1 ? 
ATOM   5998 C C    . ASN A 1 359 ? -19.284 -34.656 -12.868 1.000 11.214 0 374  ASN A C    1 ? 
ATOM   5999 O O    . ASN A 1 359 ? -20.211 -35.384 -12.443 1.000 11.331 0 374  ASN A O    1 ? 
ATOM   6000 C CB   . ASN A 1 359 ? -17.333 -34.042 -11.275 1.000 15.072 0 374  ASN A CB   1 ? 
ATOM   6001 C CG   . ASN A 1 359 ? -16.111 -34.693 -10.633 1.000 22.849 0 374  ASN A CG   1 ? 
ATOM   6002 O OD1  . ASN A 1 359 ? -15.868 -35.899 -10.789 1.000 31.307 0 374  ASN A OD1  1 ? 
ATOM   6003 N ND2  . ASN A 1 359 ? -15.332 -33.914 -9.902  1.000 28.895 0 374  ASN A ND2  1 ? 
ATOM   6004 H H    . ASN A 1 359 ? -16.311 -34.025 -13.535 1.000 10.468 0 374  ASN A H    1 c 
ATOM   6005 H HA   . ASN A 1 359 ? -17.775 -35.825 -12.136 1.000 11.797 0 374  ASN A HA   1 c 
ATOM   6006 H HB2  . ASN A 1 359 ? -17.095 -33.151 -11.601 1.000 15.508 0 374  ASN A HB2  1 c 
ATOM   6007 H HB3  . ASN A 1 359 ? -18.040 -33.946 -10.605 1.000 15.530 0 374  ASN A HB3  1 c 
ATOM   6008 H HD21 . ASN A 1 359 ? -15.538 -33.058 -9.791  1.000 26.648 0 374  ASN A HD21 1 c 
ATOM   6009 H HD22 . ASN A 1 359 ? -14.602 -34.248 -9.523  1.000 26.853 0 374  ASN A HD22 1 c 
ATOM   6010 N N    A LEU A 1 360 ? -19.514 -33.658 -13.703 0.500 10.229 0 375  LEU A N    1 ? 
ATOM   6011 N N    B LEU A 1 360 ? -19.528 -33.627 -13.678 0.500 10.134 0 375  LEU A N    1 ? 
ATOM   6012 C CA   A LEU A 1 360 ? -20.847 -33.346 -14.184 0.500 10.594 0 375  LEU A CA   1 ? 
ATOM   6013 C CA   B LEU A 1 360 ? -20.864 -33.359 -14.193 0.500 10.459 0 375  LEU A CA   1 ? 
ATOM   6014 C C    A LEU A 1 360 ? -21.387 -34.500 -15.036 0.500 10.515 0 375  LEU A C    1 ? 
ATOM   6015 C C    B LEU A 1 360 ? -21.352 -34.583 -14.953 0.500 10.308 0 375  LEU A C    1 ? 
ATOM   6016 O O    A LEU A 1 360 ? -22.562 -34.862 -14.962 0.500 10.491 0 375  LEU A O    1 ? 
ATOM   6017 O O    B LEU A 1 360 ? -22.482 -35.007 -14.785 0.500 10.399 0 375  LEU A O    1 ? 
ATOM   6018 C CB   A LEU A 1 360 ? -20.722 -32.020 -14.935 0.500 10.888 0 375  LEU A CB   1 ? 
ATOM   6019 C CB   B LEU A 1 360 ? -20.990 -32.140 -15.107 0.500 10.716 0 375  LEU A CB   1 ? 
ATOM   6020 C CG   A LEU A 1 360 ? -22.012 -31.391 -15.450 0.500 12.050 0 375  LEU A CG   1 ? 
ATOM   6021 C CG   B LEU A 1 360 ? -20.946 -30.763 -14.449 0.500 11.910 0 375  LEU A CG   1 ? 
ATOM   6022 C CD1  A LEU A 1 360 ? -22.826 -30.965 -14.255 0.500 11.577 0 375  LEU A CD1  1 ? 
ATOM   6023 C CD1  B LEU A 1 360 ? -20.879 -29.731 -15.543 0.500 13.163 0 375  LEU A CD1  1 ? 
ATOM   6024 C CD2  A LEU A 1 360 ? -21.693 -30.192 -16.326 0.500 13.663 0 375  LEU A CD2  1 ? 
ATOM   6025 C CD2  B LEU A 1 360 ? -22.167 -30.554 -13.590 0.500 12.033 0 375  LEU A CD2  1 ? 
ATOM   6026 H H    A LEU A 1 360 ? -18.816 -33.140 -13.985 0.500 10.541 0 375  LEU A H    1 c 
ATOM   6027 H H    B LEU A 1 360 ? -18.845 -33.069 -13.916 0.500 10.459 0 375  LEU A H    1 c 
ATOM   6028 H HA   A LEU A 1 360 ? -21.442 -33.223 -13.401 0.500 10.677 0 375  LEU A HA   1 c 
ATOM   6029 H HA   B LEU A 1 360 ? -21.462 -33.229 -13.415 0.500 10.417 0 375  LEU A HA   1 c 
ATOM   6030 H HB2  A LEU A 1 360 ? -20.281 -31.373 -14.338 0.500 11.074 0 375  LEU A HB2  1 c 
ATOM   6031 H HB2  B LEU A 1 360 ? -20.266 -32.184 -15.774 0.500 10.917 0 375  LEU A HB2  1 c 
ATOM   6032 H HB3  A LEU A 1 360 ? -20.121 -32.161 -15.703 0.500 11.074 0 375  LEU A HB3  1 c 
ATOM   6033 H HB3  B LEU A 1 360 ? -21.838 -32.217 -15.601 0.500 10.917 0 375  LEU A HB3  1 c 
ATOM   6034 H HG   A LEU A 1 360 ? -22.516 -32.065 -15.975 0.500 12.061 0 375  LEU A HG   1 c 
ATOM   6035 H HG   B LEU A 1 360 ? -20.133 -30.698 -13.887 0.500 11.976 0 375  LEU A HG   1 c 
ATOM   6036 H HD11 A LEU A 1 360 ? -22.952 -31.723 -13.662 0.500 11.760 0 375  LEU A HD11 1 c 
ATOM   6037 H HD11 B LEU A 1 360 ? -20.040 -29.822 -16.025 0.500 12.768 0 375  LEU A HD11 1 c 
ATOM   6038 H HD12 A LEU A 1 360 ? -23.691 -30.635 -14.549 0.500 11.760 0 375  LEU A HD12 1 c 
ATOM   6039 H HD12 B LEU A 1 360 ? -20.935 -28.842 -15.154 0.500 12.767 0 375  LEU A HD12 1 c 
ATOM   6040 H HD13 A LEU A 1 360 ? -22.357 -30.259 -13.780 0.500 11.733 0 375  LEU A HD13 1 c 
ATOM   6041 H HD13 B LEU A 1 360 ? -21.621 -29.860 -16.158 0.500 12.773 0 375  LEU A HD13 1 c 
ATOM   6042 H HD21 A LEU A 1 360 ? -21.208 -30.486 -17.115 0.500 13.167 0 375  LEU A HD21 1 c 
ATOM   6043 H HD21 B LEU A 1 360 ? -22.219 -31.258 -12.925 0.500 12.225 0 375  LEU A HD21 1 c 
ATOM   6044 H HD22 A LEU A 1 360 ? -21.147 -29.561 -15.828 0.500 13.167 0 375  LEU A HD22 1 c 
ATOM   6045 H HD22 B LEU A 1 360 ? -22.964 -30.577 -14.147 0.500 12.050 0 375  LEU A HD22 1 c 
ATOM   6046 H HD23 A LEU A 1 360 ? -22.519 -29.759 -16.597 0.500 13.174 0 375  LEU A HD23 1 c 
ATOM   6047 H HD23 B LEU A 1 360 ? -22.109 -29.692 -13.145 0.500 12.050 0 375  LEU A HD23 1 c 
ATOM   6048 N N    . LEU A 1 361 ? -20.546 -35.102 -15.881 1.000 9.616  0 376  LEU A N    1 ? 
ATOM   6049 C CA   . LEU A 1 361 ? -21.003 -36.187 -16.727 1.000 10.133 0 376  LEU A CA   1 ? 
ATOM   6050 C C    . LEU A 1 361 ? -21.185 -37.494 -15.945 1.000 9.917  0 376  LEU A C    1 ? 
ATOM   6051 O O    . LEU A 1 361 ? -22.021 -38.308 -16.329 1.000 10.865 0 376  LEU A O    1 ? 
ATOM   6052 C CB   . LEU A 1 361 ? -20.054 -36.401 -17.906 1.000 9.793  0 376  LEU A CB   1 ? 
ATOM   6053 C CG   . LEU A 1 361 ? -19.835 -35.193 -18.825 1.000 10.031 0 376  LEU A CG   1 ? 
ATOM   6054 C CD1  . LEU A 1 361 ? -18.911 -35.585 -19.960 1.000 10.345 0 376  LEU A CD1  1 ? 
ATOM   6055 C CD2  . LEU A 1 361 ? -21.150 -34.626 -19.353 1.000 11.685 0 376  LEU A CD2  1 ? 
ATOM   6056 H H    . LEU A 1 361 ? -19.688 -34.800 -15.961 1.000 10.017 0 376  LEU A H    1 c 
ATOM   6057 H HA   . LEU A 1 361 ? -21.891 -35.934 -17.087 1.000 9.954  0 376  LEU A HA   1 c 
ATOM   6058 H HB2  . LEU A 1 361 ? -19.180 -36.681 -17.549 1.000 9.925  0 376  LEU A HB2  1 c 
ATOM   6059 H HB3  . LEU A 1 361 ? -20.404 -37.144 -18.450 1.000 9.931  0 376  LEU A HB3  1 c 
ATOM   6060 H HG   . LEU A 1 361 ? -19.388 -34.483 -18.300 1.000 10.323 0 376  LEU A HG   1 c 
ATOM   6061 H HD11 . LEU A 1 361 ? -18.058 -35.876 -19.598 1.000 10.251 0 376  LEU A HD11 1 c 
ATOM   6062 H HD12 . LEU A 1 361 ? -18.771 -34.821 -20.543 1.000 10.251 0 376  LEU A HD12 1 c 
ATOM   6063 H HD13 . LEU A 1 361 ? -19.311 -36.311 -20.468 1.000 10.251 0 376  LEU A HD13 1 c 
ATOM   6064 H HD21 . LEU A 1 361 ? -21.642 -34.210 -18.625 1.000 11.161 0 376  LEU A HD21 1 c 
ATOM   6065 H HD22 . LEU A 1 361 ? -21.683 -35.343 -19.736 1.000 11.186 0 376  LEU A HD22 1 c 
ATOM   6066 H HD23 . LEU A 1 361 ? -20.965 -33.961 -20.038 1.000 11.172 0 376  LEU A HD23 1 c 
ATOM   6067 N N    . LYS A 1 362 ? -20.394 -37.704 -14.880 1.000 9.549  0 377  LYS A N    1 ? 
ATOM   6068 C CA   . LYS A 1 362 ? -20.534 -38.879 -14.026 1.000 10.614 0 377  LYS A CA   1 ? 
ATOM   6069 C C    . LYS A 1 362 ? -21.903 -38.882 -13.344 1.000 10.296 0 377  LYS A C    1 ? 
ATOM   6070 O O    . LYS A 1 362 ? -22.613 -39.892 -13.380 1.000 10.466 0 377  LYS A O    1 ? 
ATOM   6071 C CB   . LYS A 1 362 ? -19.416 -38.870 -12.981 1.000 11.298 0 377  LYS A CB   1 ? 
ATOM   6072 C CG   . LYS A 1 362 ? -19.556 -39.968 -11.907 1.000 13.616 0 377  LYS A CG   1 ? 
ATOM   6073 C CD   . LYS A 1 362 ? -18.485 -39.907 -10.821 1.000 17.552 0 377  LYS A CD   1 ? 
ATOM   6074 C CE   . LYS A 1 362 ? -18.703 -40.963 -9.755  1.000 23.805 0 377  LYS A CE   1 ? 
ATOM   6075 N NZ   . LYS A 1 362 ? -17.844 -40.720 -8.586  1.000 28.942 0 377  LYS A NZ   1 ? 
ATOM   6076 H H    . LYS A 1 362 ? -19.741 -37.096 -14.683 1.000 9.889  0 377  LYS A H    1 c 
ATOM   6077 H HA   . LYS A 1 362 ? -20.452 -39.690 -14.590 1.000 10.460 0 377  LYS A HA   1 c 
ATOM   6078 H HB2  . LYS A 1 362 ? -18.555 -38.985 -13.436 1.000 11.617 0 377  LYS A HB2  1 c 
ATOM   6079 H HB3  . LYS A 1 362 ? -19.405 -37.996 -12.534 1.000 11.607 0 377  LYS A HB3  1 c 
ATOM   6080 H HG2  . LYS A 1 362 ? -20.438 -39.887 -11.485 1.000 13.814 0 377  LYS A HG2  1 c 
ATOM   6081 H HG3  . LYS A 1 362 ? -19.513 -40.844 -12.348 1.000 13.831 0 377  LYS A HG3  1 c 
ATOM   6082 H HD2  . LYS A 1 362 ? -17.602 -40.040 -11.230 1.000 17.780 0 377  LYS A HD2  1 c 
ATOM   6083 H HD3  . LYS A 1 362 ? -18.500 -39.019 -10.402 1.000 17.820 0 377  LYS A HD3  1 c 
ATOM   6084 H HE2  . LYS A 1 362 ? -19.635 -40.955 -9.472  1.000 23.263 0 377  LYS A HE2  1 c 
ATOM   6085 H HE3  . LYS A 1 362 ? -18.502 -41.844 -10.121 1.000 23.263 0 377  LYS A HE3  1 c 
ATOM   6086 H HZ1  . LYS A 1 362 ? -18.035 -39.910 -8.228  1.000 27.171 0 377  LYS A HZ1  1 c 
ATOM   6087 H HZ2  . LYS A 1 362 ? -16.973 -40.736 -8.837  1.000 27.232 0 377  LYS A HZ2  1 c 
ATOM   6088 H HZ3  . LYS A 1 362 ? -17.985 -41.362 -7.962  1.000 27.232 0 377  LYS A HZ3  1 c 
ATOM   6089 N N    A GLU A 1 363 ? -22.333 -37.739 -12.818 0.500 10.014 0 378  GLU A N    1 ? 
ATOM   6090 N N    B GLU A 1 363 ? -22.278 -37.746 -12.761 0.500 9.821  0 378  GLU A N    1 ? 
ATOM   6091 C CA   A GLU A 1 363 ? -23.661 -37.639 -12.214 0.500 9.949  0 378  GLU A CA   1 ? 
ATOM   6092 C CA   B GLU A 1 363 ? -23.620 -37.586 -12.213 0.500 9.752  0 378  GLU A CA   1 ? 
ATOM   6093 C C    A GLU A 1 363 ? -24.756 -37.735 -13.279 0.500 9.449  0 378  GLU A C    1 ? 
ATOM   6094 C C    B GLU A 1 363 ? -24.657 -37.852 -13.303 0.500 9.537  0 378  GLU A C    1 ? 
ATOM   6095 O O    A GLU A 1 363 ? -25.826 -38.305 -13.060 0.500 8.431  0 378  GLU A O    1 ? 
ATOM   6096 O O    B GLU A 1 363 ? -25.535 -38.703 -13.108 0.500 9.057  0 378  GLU A O    1 ? 
ATOM   6097 C CB   A GLU A 1 363 ? -23.818 -36.337 -11.425 0.500 11.064 0 378  GLU A CB   1 ? 
ATOM   6098 C CB   B GLU A 1 363 ? -23.843 -36.201 -11.598 0.500 10.431 0 378  GLU A CB   1 ? 
ATOM   6099 C CG   A GLU A 1 363 ? -25.241 -36.150 -10.910 0.500 12.923 0 378  GLU A CG   1 ? 
ATOM   6100 C CG   B GLU A 1 363 ? -25.221 -36.061 -10.960 0.500 11.779 0 378  GLU A CG   1 ? 
ATOM   6101 C CD   A GLU A 1 363 ? -25.530 -35.076 -9.867  0.500 15.164 0 378  GLU A CD   1 ? 
ATOM   6102 C CD   B GLU A 1 363 ? -25.543 -34.698 -10.372 0.500 12.759 0 378  GLU A CD   1 ? 
ATOM   6103 O OE1  A GLU A 1 363 ? -24.613 -34.386 -9.374  0.500 15.359 0 378  GLU A OE1  1 ? 
ATOM   6104 O OE1  B GLU A 1 363 ? -24.873 -33.733 -10.759 0.500 14.027 0 378  GLU A OE1  1 ? 
ATOM   6105 O OE2  A GLU A 1 363 ? -26.737 -34.942 -9.519  0.500 16.471 0 378  GLU A OE2  1 ? 
ATOM   6106 O OE2  B GLU A 1 363 ? -26.373 -34.580 -9.420  0.500 15.591 0 378  GLU A OE2  1 ? 
ATOM   6107 H H    A GLU A 1 363 ? -21.793 -37.002 -12.826 0.500 10.066 0 378  GLU A H    1 c 
ATOM   6108 H H    B GLU A 1 363 ? -21.687 -37.052 -12.696 0.500 9.919  0 378  GLU A H    1 c 
ATOM   6109 H HA   A GLU A 1 363 ? -23.770 -38.396 -11.584 0.500 10.065 0 378  GLU A HA   1 c 
ATOM   6110 H HA   B GLU A 1 363 ? -23.741 -38.262 -11.499 0.500 9.846  0 378  GLU A HA   1 c 
ATOM   6111 H HB2  A GLU A 1 363 ? -23.195 -36.346 -10.669 0.500 11.188 0 378  GLU A HB2  1 c 
ATOM   6112 H HB2  B GLU A 1 363 ? -23.155 -36.041 -10.919 0.500 10.567 0 378  GLU A HB2  1 c 
ATOM   6113 H HB3  A GLU A 1 363 ? -23.578 -35.583 -12.003 0.500 11.188 0 378  GLU A HB3  1 c 
ATOM   6114 H HB3  B GLU A 1 363 ? -23.736 -35.524 -12.297 0.500 10.595 0 378  GLU A HB3  1 c 
ATOM   6115 H HG2  A GLU A 1 363 ? -25.819 -35.971 -11.682 0.500 12.940 0 378  GLU A HG2  1 c 
ATOM   6116 H HG2  B GLU A 1 363 ? -25.902 -36.272 -11.634 0.500 11.670 0 378  GLU A HG2  1 c 
ATOM   6117 H HG3  A GLU A 1 363 ? -25.543 -37.006 -10.540 0.500 12.940 0 378  GLU A HG3  1 c 
ATOM   6118 H HG3  B GLU A 1 363 ? -25.305 -36.728 -10.247 0.500 11.670 0 378  GLU A HG3  1 c 
ATOM   6119 N N    . ALA A 1 364 ? -24.506 -37.176 -14.465 1.000 9.206  0 379  ALA A N    1 ? 
ATOM   6120 C CA   . ALA A 1 364 ? -25.488 -37.294 -15.530 1.000 9.700  0 379  ALA A CA   1 ? 
ATOM   6121 C C    . ALA A 1 364 ? -25.655 -38.761 -15.910 1.000 10.005 0 379  ALA A C    1 ? 
ATOM   6122 O O    . ALA A 1 364 ? -26.776 -39.205 -16.200 1.000 10.297 0 379  ALA A O    1 ? 
ATOM   6123 C CB   . ALA A 1 364 ? -25.115 -36.438 -16.723 1.000 10.544 0 379  ALA A CB   1 ? 
ATOM   6124 H H    . ALA A 1 364 ? -23.754 -36.673 -14.596 1.000 9.420  0 379  ALA A H    1 c 
ATOM   6125 H HA   . ALA A 1 364 ? -26.362 -36.973 -15.174 1.000 9.796  0 379  ALA A HA   1 c 
ATOM   6126 H HB1  . ALA A 1 364 ? -25.067 -35.505 -16.453 1.000 10.286 0 379  ALA A HB1  1 c 
ATOM   6127 H HB2  . ALA A 1 364 ? -24.251 -36.717 -17.069 1.000 10.286 0 379  ALA A HB2  1 c 
ATOM   6128 H HB3  . ALA A 1 364 ? -25.787 -36.536 -17.418 1.000 10.286 0 379  ALA A HB3  1 c 
ATOM   6129 N N    . ALA A 1 365 ? -24.573 -39.548 -15.935 1.000 9.939  0 380  ALA A N    1 ? 
ATOM   6130 C CA   . ALA A 1 365 ? -24.631 -40.956 -16.251 1.000 9.930  0 380  ALA A CA   1 ? 
ATOM   6131 C C    . ALA A 1 365 ? -25.461 -41.708 -15.204 1.000 11.011 0 380  ALA A C    1 ? 
ATOM   6132 O O    . ALA A 1 365 ? -26.249 -42.591 -15.545 1.000 11.320 0 380  ALA A O    1 ? 
ATOM   6133 C CB   . ALA A 1 365 ? -23.247 -41.556 -16.421 1.000 10.395 0 380  ALA A CB   1 ? 
ATOM   6134 H H    . ALA A 1 365 ? -23.757 -39.179 -15.751 1.000 9.946  0 380  ALA A H    1 c 
ATOM   6135 H HA   . ALA A 1 365 ? -25.110 -41.041 -17.121 1.000 10.207 0 380  ALA A HA   1 c 
ATOM   6136 H HB1  . ALA A 1 365 ? -22.780 -41.103 -17.143 1.000 10.256 0 380  ALA A HB1  1 c 
ATOM   6137 H HB2  . ALA A 1 365 ? -22.742 -41.453 -15.597 1.000 10.257 0 380  ALA A HB2  1 c 
ATOM   6138 H HB3  . ALA A 1 365 ? -23.325 -42.502 -16.634 1.000 10.256 0 380  ALA A HB3  1 c 
ATOM   6139 N N    . SER A 1 366 ? -25.267 -41.390 -13.913 1.000 10.374 0 381  SER A N    1 ? 
ATOM   6140 C CA   . SER A 1 366 ? -26.036 -42.053 -12.858 1.000 10.501 0 381  SER A CA   1 ? 
ATOM   6141 C C    . SER A 1 366 ? -27.515 -41.720 -12.994 1.000 10.060 0 381  SER A C    1 ? 
ATOM   6142 O O    . SER A 1 366 ? -28.372 -42.612 -12.818 1.000 11.623 0 381  SER A O    1 ? 
ATOM   6143 C CB   . SER A 1 366 ? -25.526 -41.683 -11.517 1.000 12.242 0 381  SER A CB   1 ? 
ATOM   6144 O OG   . SER A 1 366 ? -24.247 -42.189 -11.207 1.000 15.303 0 381  SER A OG   1 ? 
ATOM   6145 H H    . SER A 1 366 ? -24.646 -40.760 -13.684 1.000 10.561 0 381  SER A H    1 c 
ATOM   6146 H HA   . SER A 1 366 ? -25.930 -43.031 -12.970 1.000 10.706 0 381  SER A HA   1 c 
ATOM   6147 H HB2  . SER A 1 366 ? -25.502 -40.710 -11.450 1.000 12.418 0 381  SER A HB2  1 c 
ATOM   6148 H HB3  . SER A 1 366 ? -26.159 -42.001 -10.846 1.000 12.433 0 381  SER A HB3  1 c 
ATOM   6149 H HG   . SER A 1 366 ? -24.039 -41.930 -10.428 0.000 15.320 0 381  SER A HG   1 c 
ATOM   6150 N N    . LEU A 1 367 ? -27.824 -40.464 -13.322 1.000 9.607  0 382  LEU A N    1 ? 
ATOM   6151 C CA   . LEU A 1 367 ? -29.206 -40.035 -13.476 1.000 9.654  0 382  LEU A CA   1 ? 
ATOM   6152 C C    . LEU A 1 367 ? -29.848 -40.672 -14.691 1.000 10.950 0 382  LEU A C    1 ? 
ATOM   6153 O O    . LEU A 1 367 ? -31.047 -41.011 -14.668 1.000 11.946 0 382  LEU A O    1 ? 
ATOM   6154 C CB   . LEU A 1 367 ? -29.345 -38.528 -13.508 1.000 9.375  0 382  LEU A CB   1 ? 
ATOM   6155 C CG   . LEU A 1 367 ? -29.003 -37.821 -12.187 1.000 9.994  0 382  LEU A CG   1 ? 
ATOM   6156 C CD1  . LEU A 1 367 ? -28.891 -36.315 -12.358 1.000 12.046 0 382  LEU A CD1  1 ? 
ATOM   6157 C CD2  . LEU A 1 367 ? -30.000 -38.186 -11.064 1.000 10.958 0 382  LEU A CD2  1 ? 
ATOM   6158 H H    . LEU A 1 367 ? -27.157 -39.852 -13.448 1.000 9.731  0 382  LEU A H    1 c 
ATOM   6159 H HA   . LEU A 1 367 ? -29.701 -40.369 -12.687 1.000 9.842  0 382  LEU A HA   1 c 
ATOM   6160 H HB2  . LEU A 1 367 ? -28.753 -38.178 -14.213 1.000 9.577  0 382  LEU A HB2  1 c 
ATOM   6161 H HB3  . LEU A 1 367 ? -30.274 -38.307 -13.749 1.000 9.583  0 382  LEU A HB3  1 c 
ATOM   6162 H HG   . LEU A 1 367 ? -28.112 -38.146 -11.898 1.000 10.390 0 382  LEU A HG   1 c 
ATOM   6163 H HD11 . LEU A 1 367 ? -28.190 -36.111 -12.999 1.000 11.399 0 382  LEU A HD11 1 c 
ATOM   6164 H HD12 . LEU A 1 367 ? -28.675 -35.906 -11.503 1.000 11.399 0 382  LEU A HD12 1 c 
ATOM   6165 H HD13 . LEU A 1 367 ? -29.737 -35.961 -12.680 1.000 11.399 0 382  LEU A HD13 1 c 
ATOM   6166 H HD21 . LEU A 1 367 ? -29.883 -39.117 -10.813 1.000 10.657 0 382  LEU A HD21 1 c 
ATOM   6167 H HD22 . LEU A 1 367 ? -30.910 -38.049 -11.379 1.000 10.666 0 382  LEU A HD22 1 c 
ATOM   6168 H HD23 . LEU A 1 367 ? -29.839 -37.621 -10.290 1.000 10.666 0 382  LEU A HD23 1 c 
ATOM   6169 N N    . LEU A 1 368 ? -29.088 -40.863 -15.790 1.000 11.038 0 383  LEU A N    1 ? 
ATOM   6170 C CA   . LEU A 1 368 ? -29.585 -41.556 -16.981 1.000 11.376 0 383  LEU A CA   1 ? 
ATOM   6171 C C    . LEU A 1 368 ? -29.905 -43.005 -16.651 1.000 12.945 0 383  LEU A C    1 ? 
ATOM   6172 O O    . LEU A 1 368 ? -30.958 -43.483 -17.100 1.000 14.112 0 383  LEU A O    1 ? 
ATOM   6173 C CB   . LEU A 1 368 ? -28.550 -41.442 -18.104 1.000 11.652 0 383  LEU A CB   1 ? 
ATOM   6174 C CG   . LEU A 1 368 ? -28.996 -42.002 -19.455 1.000 13.060 0 383  LEU A CG   1 ? 
ATOM   6175 C CD1  . LEU A 1 368 ? -30.111 -41.206 -20.084 1.000 15.728 0 383  LEU A CD1  1 ? 
ATOM   6176 C CD2  . LEU A 1 368 ? -27.799 -42.060 -20.396 1.000 14.805 0 383  LEU A CD2  1 ? 
ATOM   6177 H H    . LEU A 1 368 ? -28.232 -40.542 -15.798 1.000 11.075 0 383  LEU A H    1 c 
ATOM   6178 H HA   . LEU A 1 368 ? -30.421 -41.112 -17.266 1.000 11.727 0 383  LEU A HA   1 c 
ATOM   6179 H HB2  . LEU A 1 368 ? -28.324 -40.490 -18.219 1.000 11.899 0 383  LEU A HB2  1 c 
ATOM   6180 H HB3  . LEU A 1 368 ? -27.735 -41.918 -17.822 1.000 11.922 0 383  LEU A HB3  1 c 
ATOM   6181 H HG   . LEU A 1 368 ? -29.321 -42.929 -19.316 1.000 13.553 0 383  LEU A HG   1 c 
ATOM   6182 H HD11 . LEU A 1 368 ? -30.845 -41.115 -19.455 1.000 14.889 0 383  LEU A HD11 1 c 
ATOM   6183 H HD12 . LEU A 1 368 ? -30.426 -41.664 -20.882 1.000 14.894 0 383  LEU A HD12 1 c 
ATOM   6184 H HD13 . LEU A 1 368 ? -29.783 -40.323 -20.327 1.000 14.885 0 383  LEU A HD13 1 c 
ATOM   6185 H HD21 . LEU A 1 368 ? -27.117 -42.640 -20.019 1.000 14.251 0 383  LEU A HD21 1 c 
ATOM   6186 H HD22 . LEU A 1 368 ? -27.435 -41.167 -20.514 1.000 14.264 0 383  LEU A HD22 1 c 
ATOM   6187 H HD23 . LEU A 1 368 ? -28.081 -42.411 -21.258 1.000 14.264 0 383  LEU A HD23 1 c 
ATOM   6188 N N    . GLU A 1 369 ? -29.064 -43.670 -15.871 1.000 13.342 0 384  GLU A N    1 ? 
ATOM   6189 C CA   . GLU A 1 369 ? -29.326 -45.043 -15.450 1.000 15.024 0 384  GLU A CA   1 ? 
ATOM   6190 C C    . GLU A 1 369 ? -30.651 -45.126 -14.691 1.000 16.420 0 384  GLU A C    1 ? 
ATOM   6191 O O    . GLU A 1 369 ? -31.369 -46.131 -14.839 1.000 20.349 0 384  GLU A O    1 ? 
ATOM   6192 C CB   . GLU A 1 369 ? -28.152 -45.568 -14.614 1.000 18.780 0 384  GLU A CB   1 ? 
ATOM   6193 C CG   . GLU A 1 369 ? -28.310 -47.025 -14.163 1.000 22.983 0 384  GLU A CG   1 ? 
ATOM   6194 C CD   . GLU A 1 369 ? -27.174 -47.641 -13.338 1.000 28.970 0 384  GLU A CD   1 ? 
ATOM   6195 O OE1  . GLU A 1 369 ? -27.335 -48.141 -12.193 1.000 32.089 0 384  GLU A OE1  1 ? 
ATOM   6196 O OE2  . GLU A 1 369 ? -26.070 -47.616 -13.892 1.000 33.524 0 384  GLU A OE2  1 ? 
ATOM   6197 H H    . GLU A 1 369 ? -28.295 -43.263 -15.592 1.000 13.600 0 384  GLU A H    1 c 
ATOM   6198 H HA   . GLU A 1 369 ? -29.399 -45.604 -16.263 1.000 15.614 0 384  GLU A HA   1 c 
ATOM   6199 H HB2  . GLU A 1 369 ? -27.330 -45.487 -15.140 1.000 18.678 0 384  GLU A HB2  1 c 
ATOM   6200 H HB3  . GLU A 1 369 ? -28.054 -45.003 -13.820 1.000 18.639 0 384  GLU A HB3  1 c 
ATOM   6201 H HG2  . GLU A 1 369 ? -29.133 -47.098 -13.635 1.000 23.095 0 384  GLU A HG2  1 c 
ATOM   6202 H HG3  . GLU A 1 369 ? -28.441 -47.580 -14.957 1.000 23.136 0 384  GLU A HG3  1 c 
ATOM   6203 N N    . ALA A 1 370 ? -30.985 -44.093 -13.905 1.000 15.974 0 385  ALA A N    1 ? 
ATOM   6204 C CA   . ALA A 1 370 ? -32.224 -44.031 -13.146 1.000 17.481 0 385  ALA A CA   1 ? 
ATOM   6205 C C    . ALA A 1 370 ? -33.403 -43.511 -13.971 1.000 17.700 0 385  ALA A C    1 ? 
ATOM   6206 O O    . ALA A 1 370 ? -34.499 -43.313 -13.459 1.000 18.975 0 385  ALA A O    1 ? 
ATOM   6207 C CB   . ALA A 1 370 ? -31.986 -43.181 -11.946 1.000 18.539 0 385  ALA A CB   1 ? 
ATOM   6208 H H    . ALA A 1 370 ? -30.401 -43.394 -13.833 1.000 16.350 0 385  ALA A H    1 c 
ATOM   6209 H HA   . ALA A 1 370 ? -32.447 -44.955 -12.843 1.000 17.416 0 385  ALA A HA   1 c 
ATOM   6210 H HB1  . ALA A 1 370 ? -31.251 -43.546 -11.426 1.000 18.212 0 385  ALA A HB1  1 c 
ATOM   6211 H HB2  . ALA A 1 370 ? -31.764 -42.276 -12.225 1.000 18.202 0 385  ALA A HB2  1 c 
ATOM   6212 H HB3  . ALA A 1 370 ? -32.788 -43.159 -11.396 1.000 18.216 0 385  ALA A HB3  1 c 
ATOM   6213 N N    . GLY A 1 371 ? -33.217 -43.289 -15.279 1.000 16.719 0 386  GLY A N    1 ? 
ATOM   6214 C CA   . GLY A 1 371 ? -34.321 -43.061 -16.218 1.000 18.106 0 386  GLY A CA   1 ? 
ATOM   6215 C C    . GLY A 1 371 ? -34.588 -41.582 -16.504 1.000 19.492 0 386  GLY A C    1 ? 
ATOM   6216 O O    . GLY A 1 371 ? -35.668 -41.197 -16.940 1.000 22.364 0 386  GLY A O    1 ? 
ATOM   6217 H H    . GLY A 1 371 ? -32.365 -43.265 -15.605 1.000 17.207 0 386  GLY A H    1 c 
ATOM   6218 H HA2  . GLY A 1 371 ? -34.114 -43.521 -17.064 1.000 18.107 0 386  GLY A HA2  1 c 
ATOM   6219 H HA3  . GLY A 1 371 ? -35.139 -43.471 -15.854 1.000 18.091 0 386  GLY A HA3  1 c 
ATOM   6220 N N    . SER A 1 372 ? -33.611 -40.699 -16.309 1.000 16.227 0 399  SER A N    1 ? 
ATOM   6221 C CA   . SER A 1 372 ? -33.782 -39.313 -16.674 1.000 15.219 0 399  SER A CA   1 ? 
ATOM   6222 C C    . SER A 1 372 ? -34.120 -39.172 -18.160 1.000 17.269 0 399  SER A C    1 ? 
ATOM   6223 O O    . SER A 1 372 ? -33.604 -39.920 -19.008 1.000 17.270 0 399  SER A O    1 ? 
ATOM   6224 C CB   . SER A 1 372 ? -32.580 -38.469 -16.288 1.000 17.607 0 399  SER A CB   1 ? 
ATOM   6225 O OG   . SER A 1 372 ? -31.447 -38.780 -17.104 1.000 22.255 0 399  SER A OG   1 ? 
ATOM   6226 H H    . SER A 1 372 ? -32.818 -40.967 -15.941 1.000 16.726 0 399  SER A H    1 c 
ATOM   6227 H HA   . SER A 1 372 ? -34.558 -38.973 -16.161 1.000 16.273 0 399  SER A HA   1 c 
ATOM   6228 H HB2  . SER A 1 372 ? -32.804 -37.525 -16.389 1.000 18.021 0 399  SER A HB2  1 c 
ATOM   6229 H HB3  . SER A 1 372 ? -32.360 -38.632 -15.351 1.000 18.021 0 399  SER A HB3  1 c 
ATOM   6230 H HG   . SER A 1 372 ? -30.800 -38.292 -16.863 0.000 22.270 0 399  SER A HG   1 c 
ATOM   6231 N N    . GLN A 1 373 ? -34.967 -38.175 -18.422 1.000 18.083 0 400  GLN A N    1 ? 
ATOM   6232 C CA   . GLN A 1 373 ? -35.400 -37.795 -19.753 1.000 21.239 0 400  GLN A CA   1 ? 
ATOM   6233 C C    . GLN A 1 373 ? -34.763 -36.450 -20.089 1.000 18.842 0 400  GLN A C    1 ? 
ATOM   6234 O O    . GLN A 1 373 ? -34.506 -35.618 -19.204 1.000 23.590 0 400  GLN A O    1 ? 
ATOM   6235 C CB   . GLN A 1 373 ? -36.929 -37.613 -19.823 1.000 25.041 0 400  GLN A CB   1 ? 
ATOM   6236 C CG   . GLN A 1 373 ? -37.781 -38.875 -19.721 1.000 30.593 0 400  GLN A CG   1 ? 
ATOM   6237 C CD   . GLN A 1 373 ? -39.275 -38.582 -19.818 1.000 40.174 0 400  GLN A CD   1 ? 
ATOM   6238 O OE1  . GLN A 1 373 ? -39.757 -37.938 -20.763 1.000 46.008 0 400  GLN A OE1  1 ? 
ATOM   6239 N NE2  . GLN A 1 373 ? -40.038 -39.023 -18.826 1.000 42.098 0 400  GLN A NE2  1 ? 
ATOM   6240 H H    . GLN A 1 373 ? -35.297 -37.695 -17.717 1.000 18.507 0 400  GLN A H    1 c 
ATOM   6241 H HA   . GLN A 1 373 ? -35.101 -38.480 -20.404 1.000 20.681 0 400  GLN A HA   1 c 
ATOM   6242 H HB2  . GLN A 1 373 ? -37.193 -37.004 -19.102 1.000 25.247 0 400  GLN A HB2  1 c 
ATOM   6243 H HB3  . GLN A 1 373 ? -37.142 -37.167 -20.670 1.000 25.214 0 400  GLN A HB3  1 c 
ATOM   6244 H HG2  . GLN A 1 373 ? -37.533 -39.493 -20.441 1.000 31.139 0 400  GLN A HG2  1 c 
ATOM   6245 H HG3  . GLN A 1 373 ? -37.597 -39.322 -18.868 1.000 31.232 0 400  GLN A HG3  1 c 
ATOM   6246 H HE21 . GLN A 1 373 ? -39.794 -39.736 -18.358 1.000 41.314 0 400  GLN A HE21 1 c 
ATOM   6247 H HE22 . GLN A 1 373 ? -40.796 -38.603 -18.633 1.000 41.484 0 400  GLN A HE22 1 c 
ATOM   6248 N N    . GLY A 1 374 ? -34.530 -36.243 -21.396 1.000 19.879 0 401  GLY A N    1 ? 
ATOM   6249 C CA   . GLY A 1 374 ? -33.945 -35.019 -21.924 1.000 20.716 0 401  GLY A CA   1 ? 
ATOM   6250 C C    . GLY A 1 374 ? -32.480 -34.837 -21.510 1.000 17.597 0 401  GLY A C    1 ? 
ATOM   6251 O O    . GLY A 1 374 ? -32.016 -33.703 -21.512 1.000 18.612 0 401  GLY A O    1 ? 
ATOM   6252 H H    . GLY A 1 374 ? -34.751 -36.903 -21.988 1.000 19.828 0 401  GLY A H    1 c 
ATOM   6253 H HA2  . GLY A 1 374 ? -34.006 -35.036 -22.908 1.000 19.782 0 401  GLY A HA2  1 c 
ATOM   6254 H HA3  . GLY A 1 374 ? -34.472 -34.250 -21.603 1.000 19.782 0 401  GLY A HA3  1 c 
ATOM   6255 N N    . SER A 1 375 ? -31.829 -35.936 -21.125 1.000 15.754 0 402  SER A N    1 ? 
ATOM   6256 C CA   . SER A 1 375 ? -30.449 -35.943 -20.626 1.000 14.199 0 402  SER A CA   1 ? 
ATOM   6257 C C    . SER A 1 375 ? -29.523 -35.308 -21.665 1.000 13.507 0 402  SER A C    1 ? 
ATOM   6258 O O    . SER A 1 375 ? -29.593 -35.647 -22.848 1.000 13.554 0 402  SER A O    1 ? 
ATOM   6259 C CB   . SER A 1 375 ? -29.968 -37.333 -20.304 1.000 14.240 0 402  SER A CB   1 ? 
ATOM   6260 O OG   . SER A 1 375 ? -28.604 -37.283 -19.875 1.000 15.667 0 402  SER A OG   1 ? 
ATOM   6261 H H    . SER A 1 375 ? -32.260 -36.739 -21.190 1.000 15.863 0 402  SER A H    1 c 
ATOM   6262 H HA   . SER A 1 375 ? -30.416 -35.398 -19.800 1.000 14.338 0 402  SER A HA   1 c 
ATOM   6263 H HB2  . SER A 1 375 ? -30.521 -37.715 -19.597 1.000 14.562 0 402  SER A HB2  1 c 
ATOM   6264 H HB3  . SER A 1 375 ? -30.042 -37.897 -21.097 1.000 14.577 0 402  SER A HB3  1 c 
ATOM   6265 H HG   . SER A 1 375 ? -28.349 -38.070 -19.699 0.000 15.670 0 402  SER A HG   1 c 
ATOM   6266 N N    . ALA A 1 376 ? -28.544 -34.523 -21.207 1.000 12.288 0 403  ALA A N    1 ? 
ATOM   6267 C CA   . ALA A 1 376 ? -27.490 -34.034 -22.068 1.000 12.850 0 403  ALA A CA   1 ? 
ATOM   6268 C C    . ALA A 1 376 ? -26.792 -35.216 -22.716 1.000 11.067 0 403  ALA A C    1 ? 
ATOM   6269 O O    . ALA A 1 376 ? -26.330 -35.077 -23.851 1.000 11.262 0 403  ALA A O    1 ? 
ATOM   6270 C CB   . ALA A 1 376 ? -26.493 -33.215 -21.246 1.000 12.942 0 403  ALA A CB   1 ? 
ATOM   6271 H H    . ALA A 1 376 ? -28.538 -34.284 -20.324 1.000 12.720 0 403  ALA A H    1 c 
ATOM   6272 H HA   . ALA A 1 376 ? -27.892 -33.465 -22.781 1.000 12.410 0 403  ALA A HA   1 c 
ATOM   6273 H HB1  . ALA A 1 376 ? -26.949 -32.460 -20.837 1.000 12.915 0 403  ALA A HB1  1 c 
ATOM   6274 H HB2  . ALA A 1 376 ? -26.107 -33.772 -20.549 1.000 12.915 0 403  ALA A HB2  1 c 
ATOM   6275 H HB3  . ALA A 1 376 ? -25.784 -32.887 -21.824 1.000 12.915 0 403  ALA A HB3  1 c 
ATOM   6276 N N    . LEU A 1 377 ? -26.728 -36.364 -22.063 1.000 10.950 0 404  LEU A N    1 ? 
ATOM   6277 C CA   . LEU A 1 377 ? -25.955 -37.498 -22.574 1.000 10.736 0 404  LEU A CA   1 ? 
ATOM   6278 C C    . LEU A 1 377 ? -26.647 -38.147 -23.775 1.000 10.818 0 404  LEU A C    1 ? 
ATOM   6279 O O    . LEU A 1 377 ? -26.001 -38.946 -24.471 1.000 11.563 0 404  LEU A O    1 ? 
ATOM   6280 C CB   . LEU A 1 377 ? -25.605 -38.538 -21.518 1.000 11.493 0 404  LEU A CB   1 ? 
ATOM   6281 C CG   . LEU A 1 377 ? -24.746 -38.052 -20.343 1.000 12.549 0 404  LEU A CG   1 ? 
ATOM   6282 C CD1  . LEU A 1 377 ? -24.497 -39.177 -19.387 1.000 14.039 0 404  LEU A CD1  1 ? 
ATOM   6283 C CD2  . LEU A 1 377 ? -23.455 -37.465 -20.870 1.000 14.806 0 404  LEU A CD2  1 ? 
ATOM   6284 H H    . LEU A 1 377 ? -27.157 -36.454 -21.261 1.000 10.965 0 404  LEU A H    1 c 
ATOM   6285 H HA   . LEU A 1 377 ? -25.104 -37.127 -22.919 1.000 10.966 0 404  LEU A HA   1 c 
ATOM   6286 H HB2  . LEU A 1 377 ? -26.446 -38.902 -21.157 1.000 11.541 0 404  LEU A HB2  1 c 
ATOM   6287 H HB3  . LEU A 1 377 ? -25.131 -39.279 -21.962 1.000 11.538 0 404  LEU A HB3  1 c 
ATOM   6288 H HG   . LEU A 1 377 ? -25.243 -37.338 -19.865 1.000 13.008 0 404  LEU A HG   1 c 
ATOM   6289 H HD11 . LEU A 1 377 ? -25.346 -39.507 -19.047 1.000 13.576 0 404  LEU A HD11 1 c 
ATOM   6290 H HD12 . LEU A 1 377 ? -23.954 -38.860 -18.646 1.000 13.578 0 404  LEU A HD12 1 c 
ATOM   6291 H HD13 . LEU A 1 377 ? -24.031 -39.896 -19.845 1.000 13.576 0 404  LEU A HD13 1 c 
ATOM   6292 H HD21 . LEU A 1 377 ? -23.626 -36.585 -21.245 1.000 14.041 0 404  LEU A HD21 1 c 
ATOM   6293 H HD22 . LEU A 1 377 ? -23.092 -38.046 -21.561 1.000 14.062 0 404  LEU A HD22 1 c 
ATOM   6294 H HD23 . LEU A 1 377 ? -22.813 -37.387 -20.144 1.000 14.055 0 404  LEU A HD23 1 c 
ATOM   6295 N N    . GLN A 1 378 ? -27.928 -37.839 -23.970 1.000 10.938 0 405  GLN A N    1 ? 
ATOM   6296 C CA   . GLN A 1 378 ? -28.639 -38.354 -25.130 1.000 11.790 0 405  GLN A CA   1 ? 
ATOM   6297 C C    . GLN A 1 378 ? -28.914 -37.264 -26.141 1.000 11.914 0 405  GLN A C    1 ? 
ATOM   6298 O O    . GLN A 1 378 ? -29.632 -37.493 -27.124 1.000 13.043 0 405  GLN A O    1 ? 
ATOM   6299 C CB   . GLN A 1 378 ? -29.950 -39.019 -24.692 1.000 13.178 0 405  GLN A CB   1 ? 
ATOM   6300 C CG   . GLN A 1 378 ? -29.642 -40.310 -23.943 1.000 15.108 0 405  GLN A CG   1 ? 
ATOM   6301 C CD   . GLN A 1 378 ? -30.850 -41.151 -23.625 1.000 17.716 0 405  GLN A CD   1 ? 
ATOM   6302 O OE1  . GLN A 1 378 ? -31.922 -40.632 -23.300 1.000 18.805 0 405  GLN A OE1  1 ? 
ATOM   6303 N NE2  . GLN A 1 378 ? -30.623 -42.454 -23.677 1.000 18.862 0 405  GLN A NE2  1 ? 
ATOM   6304 H H    . GLN A 1 378 ? -28.378 -37.319 -23.368 1.000 11.102 0 405  GLN A H    1 c 
ATOM   6305 H HA   . GLN A 1 378 ? -28.076 -39.041 -25.563 1.000 11.911 0 405  GLN A HA   1 c 
ATOM   6306 H HB2  . GLN A 1 378 ? -30.450 -38.410 -24.108 1.000 13.256 0 405  GLN A HB2  1 c 
ATOM   6307 H HB3  . GLN A 1 378 ? -30.502 -39.218 -25.476 1.000 13.249 0 405  GLN A HB3  1 c 
ATOM   6308 H HG2  . GLN A 1 378 ? -29.021 -40.849 -24.478 1.000 15.237 0 405  GLN A HG2  1 c 
ATOM   6309 H HG3  . GLN A 1 378 ? -29.189 -40.090 -23.101 1.000 15.182 0 405  GLN A HG3  1 c 
ATOM   6310 H HE21 . GLN A 1 378 ? -29.859 -42.784 -23.369 1.000 18.446 0 405  GLN A HE21 1 c 
ATOM   6311 H HE22 . GLN A 1 378 ? -31.237 -42.996 -24.020 1.000 18.488 0 405  GLN A HE22 1 c 
ATOM   6312 N N    . ASP A 1 379 ? -28.279 -36.097 -25.990 1.000 10.114 0 406  ASP A N    1 ? 
ATOM   6313 C CA   . ASP A 1 379 ? -28.476 -34.953 -26.852 1.000 10.564 0 406  ASP A CA   1 ? 
ATOM   6314 C C    . ASP A 1 379 ? -27.254 -34.768 -27.733 1.000 10.597 0 406  ASP A C    1 ? 
ATOM   6315 O O    . ASP A 1 379 ? -26.186 -34.382 -27.254 1.000 9.457  0 406  ASP A O    1 ? 
ATOM   6316 C CB   . ASP A 1 379 ? -28.751 -33.687 -26.054 1.000 11.414 0 406  ASP A CB   1 ? 
ATOM   6317 C CG   . ASP A 1 379 ? -29.032 -32.452 -26.899 1.000 13.066 0 406  ASP A CG   1 ? 
ATOM   6318 O OD1  . ASP A 1 379 ? -28.939 -32.531 -28.140 1.000 13.380 0 406  ASP A OD1  1 ? 
ATOM   6319 O OD2  . ASP A 1 379 ? -29.386 -31.407 -26.313 1.000 16.644 0 406  ASP A OD2  1 ? 
ATOM   6320 H H    . ASP A 1 379 ? -27.679 -36.014 -25.306 1.000 10.634 0 406  ASP A H    1 c 
ATOM   6321 H HA   . ASP A 1 379 ? -29.260 -35.121 -27.419 1.000 10.675 0 406  ASP A HA   1 c 
ATOM   6322 H HB2  . ASP A 1 379 ? -29.524 -33.843 -25.473 1.000 11.569 0 406  ASP A HB2  1 c 
ATOM   6323 H HB3  . ASP A 1 379 ? -27.978 -33.498 -25.481 1.000 11.556 0 406  ASP A HB3  1 c 
ATOM   6324 N N    . PRO A 1 380 ? -27.309 -35.063 -29.036 1.000 9.985  0 407  PRO A N    1 ? 
ATOM   6325 C CA   . PRO A 1 380 ? -26.152 -34.857 -29.890 1.000 10.682 0 407  PRO A CA   1 ? 
ATOM   6326 C C    . PRO A 1 380 ? -25.638 -33.415 -29.891 1.000 10.611 0 407  PRO A C    1 ? 
ATOM   6327 O O    . PRO A 1 380 ? -24.441 -33.207 -30.135 1.000 10.838 0 407  PRO A O    1 ? 
ATOM   6328 C CB   . PRO A 1 380 ? -26.575 -35.309 -31.272 1.000 12.239 0 407  PRO A CB   1 ? 
ATOM   6329 C CG   . PRO A 1 380 ? -28.000 -35.483 -31.185 1.000 15.208 0 407  PRO A CG   1 ? 
ATOM   6330 C CD   . PRO A 1 380 ? -28.503 -35.480 -29.787 1.000 11.732 0 407  PRO A CD   1 ? 
ATOM   6331 H HA   . PRO A 1 380 ? -25.430 -35.455 -29.570 1.000 10.791 0 407  PRO A HA   1 c 
ATOM   6332 H HB2  . PRO A 1 380 ? -26.347 -34.630 -31.950 1.000 12.493 0 407  PRO A HB2  1 c 
ATOM   6333 H HB3  . PRO A 1 380 ? -26.133 -36.155 -31.513 1.000 12.500 0 407  PRO A HB3  1 c 
ATOM   6334 H HG2  . PRO A 1 380 ? -28.443 -34.767 -31.685 1.000 13.766 0 407  PRO A HG2  1 c 
ATOM   6335 H HG3  . PRO A 1 380 ? -28.247 -36.331 -31.612 1.000 13.638 0 407  PRO A HG3  1 c 
ATOM   6336 H HD2  . PRO A 1 380 ? -29.239 -34.838 -29.676 1.000 11.987 0 407  PRO A HD2  1 c 
ATOM   6337 H HD3  . PRO A 1 380 ? -28.804 -36.376 -29.514 1.000 11.994 0 407  PRO A HD3  1 c 
ATOM   6338 N N    . GLU A 1 381 ? -26.493 -32.417 -29.656 1.000 10.530 0 408  GLU A N    1 ? 
ATOM   6339 C CA   . GLU A 1 381 ? -25.983 -31.046 -29.588 1.000 11.088 0 408  GLU A CA   1 ? 
ATOM   6340 C C    . GLU A 1 381 ? -25.034 -30.864 -28.406 1.000 10.472 0 408  GLU A C    1 ? 
ATOM   6341 O O    . GLU A 1 381 ? -24.073 -30.085 -28.484 1.000 10.426 0 408  GLU A O    1 ? 
ATOM   6342 C CB   . GLU A 1 381 ? -27.132 -30.053 -29.500 1.000 14.816 0 408  GLU A CB   1 ? 
ATOM   6343 C CG   . GLU A 1 381 ? -28.013 -30.060 -30.736 1.000 22.775 0 408  GLU A CG   1 ? 
ATOM   6344 C CD   . GLU A 1 381 ? -29.057 -28.973 -30.830 1.000 35.309 0 408  GLU A CD   1 ? 
ATOM   6345 O OE1  . GLU A 1 381 ? -29.315 -28.623 -32.016 1.000 49.233 0 408  GLU A OE1  1 ? 
ATOM   6346 O OE2  . GLU A 1 381 ? -29.587 -28.509 -29.781 1.000 41.849 0 408  GLU A OE2  1 ? 
ATOM   6347 H H    . GLU A 1 381 ? -27.385 -32.577 -29.544 1.000 10.805 0 408  GLU A H    1 c 
ATOM   6348 H HA   . GLU A 1 381 ? -25.481 -30.862 -30.422 1.000 11.457 0 408  GLU A HA   1 c 
ATOM   6349 H HB2  . GLU A 1 381 ? -27.676 -30.266 -28.714 1.000 15.306 0 408  GLU A HB2  1 c 
ATOM   6350 H HB3  . GLU A 1 381 ? -26.764 -29.153 -29.375 1.000 15.283 0 408  GLU A HB3  1 c 
ATOM   6351 H HG2  . GLU A 1 381 ? -27.438 -29.998 -31.528 1.000 22.932 0 408  GLU A HG2  1 c 
ATOM   6352 H HG3  . GLU A 1 381 ? -28.473 -30.925 -30.786 1.000 22.664 0 408  GLU A HG3  1 c 
ATOM   6353 N N    . CYS A 1 382 ? -25.258 -31.581 -27.314 1.000 9.087  0 409  CYS A N    1 ? 
ATOM   6354 C CA   . CYS A 1 382 ? -24.358 -31.511 -26.182 1.000 8.963  0 409  CYS A CA   1 ? 
ATOM   6355 C C    . CYS A 1 382 ? -23.030 -32.196 -26.495 1.000 8.774  0 409  CYS A C    1 ? 
ATOM   6356 O O    . CYS A 1 382 ? -21.963 -31.756 -26.045 1.000 8.658  0 409  CYS A O    1 ? 
ATOM   6357 C CB   . CYS A 1 382 ? -24.969 -32.149 -24.964 1.000 9.596  0 409  CYS A CB   1 ? 
ATOM   6358 S SG   . CYS A 1 382 ? -26.351 -31.176 -24.295 1.000 14.152 0 409  CYS A SG   1 ? 
ATOM   6359 H H    . CYS A 1 382 ? -25.992 -32.123 -27.266 1.000 9.401  0 409  CYS A H    1 c 
ATOM   6360 H HA   . CYS A 1 382 ? -24.182 -30.556 -25.985 1.000 9.080  0 409  CYS A HA   1 c 
ATOM   6361 H HB2  . CYS A 1 382 ? -25.297 -33.046 -25.196 1.000 10.157 0 409  CYS A HB2  1 c 
ATOM   6362 H HB3  . CYS A 1 382 ? -24.283 -32.244 -24.267 1.000 10.154 0 409  CYS A HB3  1 c 
ATOM   6363 H HG   . CYS A 1 382 ? -26.625 -31.904 -23.367 0.000 14.160 0 409  CYS A HG   1 c 
ATOM   6364 N N    . PHE A 1 383 ? -23.076 -33.357 -27.182 1.000 8.249  0 410  PHE A N    1 ? 
ATOM   6365 C CA   . PHE A 1 383 ? -21.823 -33.960 -27.634 1.000 8.441  0 410  PHE A CA   1 ? 
ATOM   6366 C C    . PHE A 1 383 ? -21.078 -32.962 -28.527 1.000 8.276  0 410  PHE A C    1 ? 
ATOM   6367 O O    . PHE A 1 383 ? -19.871 -32.815 -28.404 1.000 7.532  0 410  PHE A O    1 ? 
ATOM   6368 C CB   . PHE A 1 383 ? -22.122 -35.251 -28.395 1.000 8.193  0 410  PHE A CB   1 ? 
ATOM   6369 C CG   . PHE A 1 383 ? -20.889 -36.025 -28.817 1.000 7.819  0 410  PHE A CG   1 ? 
ATOM   6370 C CD1  . PHE A 1 383 ? -19.941 -36.461 -27.888 1.000 9.510  0 410  PHE A CD1  1 ? 
ATOM   6371 C CD2  . PHE A 1 383 ? -20.631 -36.273 -30.144 1.000 8.576  0 410  PHE A CD2  1 ? 
ATOM   6372 C CE1  . PHE A 1 383 ? -18.799 -37.144 -28.320 1.000 9.627  0 410  PHE A CE1  1 ? 
ATOM   6373 C CE2  . PHE A 1 383 ? -19.523 -36.967 -30.526 1.000 8.998  0 410  PHE A CE2  1 ? 
ATOM   6374 C CZ   . PHE A 1 383 ? -18.604 -37.400 -29.626 1.000 9.631  0 410  PHE A CZ   1 ? 
ATOM   6375 H H    . PHE A 1 383 ? -23.872 -33.769 -27.362 1.000 8.421  0 410  PHE A H    1 c 
ATOM   6376 H HA   . PHE A 1 383 ? -21.262 -34.172 -26.841 1.000 8.335  0 410  PHE A HA   1 c 
ATOM   6377 H HB2  . PHE A 1 383 ? -22.678 -35.826 -27.824 1.000 8.162  0 410  PHE A HB2  1 c 
ATOM   6378 H HB3  . PHE A 1 383 ? -22.647 -35.025 -29.195 1.000 8.166  0 410  PHE A HB3  1 c 
ATOM   6379 H HD1  . PHE A 1 383 ? -20.070 -36.291 -26.968 1.000 9.111  0 410  PHE A HD1  1 c 
ATOM   6380 H HD2  . PHE A 1 383 ? -21.254 -35.995 -30.796 1.000 8.559  0 410  PHE A HD2  1 c 
ATOM   6381 H HE1  . PHE A 1 383 ? -18.172 -37.451 -27.685 1.000 9.575  0 410  PHE A HE1  1 c 
ATOM   6382 H HE2  . PHE A 1 383 ? -19.381 -37.134 -31.445 1.000 9.038  0 410  PHE A HE2  1 c 
ATOM   6383 H HZ   . PHE A 1 383 ? -17.835 -37.867 -29.913 1.000 9.461  0 410  PHE A HZ   1 c 
ATOM   6384 N N    . ALA A 1 384 ? -21.770 -32.278 -29.443 1.000 8.336  0 411  ALA A N    1 ? 
ATOM   6385 C CA   . ALA A 1 384 ? -21.125 -31.276 -30.285 1.000 8.525  0 411  ALA A CA   1 ? 
ATOM   6386 C C    . ALA A 1 384 ? -20.467 -30.163 -29.457 1.000 7.708  0 411  ALA A C    1 ? 
ATOM   6387 O O    . ALA A 1 384 ? -19.368 -29.718 -29.800 1.000 7.795  0 411  ALA A O    1 ? 
ATOM   6388 C CB   . ALA A 1 384 ? -22.107 -30.711 -31.311 1.000 9.290  0 411  ALA A CB   1 ? 
ATOM   6389 H H    . ALA A 1 384 ? -22.662 -32.441 -29.552 1.000 8.369  0 411  ALA A H    1 c 
ATOM   6390 H HA   . ALA A 1 384 ? -20.397 -31.738 -30.783 1.000 8.459  0 411  ALA A HA   1 c 
ATOM   6391 H HB1  . ALA A 1 384 ? -22.440 -31.429 -31.874 1.000 9.060  0 411  ALA A HB1  1 c 
ATOM   6392 H HB2  . ALA A 1 384 ? -22.853 -30.289 -30.853 1.000 9.066  0 411  ALA A HB2  1 c 
ATOM   6393 H HB3  . ALA A 1 384 ? -21.656 -30.051 -31.865 1.000 9.060  0 411  ALA A HB3  1 c 
ATOM   6394 N N    . HIS A 1 385 ? -21.149 -29.716 -28.372 1.000 7.715  0 412  HIS A N    1 ? 
ATOM   6395 C CA   . HIS A 1 385 ? -20.498 -28.700 -27.527 1.000 7.981  0 412  HIS A CA   1 ? 
ATOM   6396 C C    . HIS A 1 385 ? -19.206 -29.231 -26.911 1.000 7.491  0 412  HIS A C    1 ? 
ATOM   6397 O O    . HIS A 1 385 ? -18.215 -28.500 -26.820 1.000 7.833  0 412  HIS A O    1 ? 
ATOM   6398 C CB   . HIS A 1 385 ? -21.382 -28.226 -26.373 1.000 9.223  0 412  HIS A CB   1 ? 
ATOM   6399 C CG   . HIS A 1 385 ? -22.648 -27.574 -26.771 1.000 12.167 0 412  HIS A CG   1 ? 
ATOM   6400 N ND1  . HIS A 1 385 ? -22.752 -26.791 -27.874 1.000 13.749 0 412  HIS A ND1  1 ? 
ATOM   6401 C CD2  . HIS A 1 385 ? -23.844 -27.590 -26.175 1.000 14.212 0 412  HIS A CD2  1 ? 
ATOM   6402 C CE1  . HIS A 1 385 ? -24.044 -26.340 -27.906 1.000 15.211 0 412  HIS A CE1  1 ? 
ATOM   6403 N NE2  . HIS A 1 385 ? -24.698 -26.866 -26.935 1.000 16.653 0 412  HIS A NE2  1 ? 
ATOM   6404 H H    . HIS A 1 385 ? -21.985 -30.025 -28.166 1.000 7.798  0 412  HIS A H    1 c 
ATOM   6405 H HA   . HIS A 1 385 ? -20.274 -27.922 -28.097 1.000 8.066  0 412  HIS A HA   1 c 
ATOM   6406 H HB2  . HIS A 1 385 ? -21.593 -29.001 -25.807 1.000 9.517  0 412  HIS A HB2  1 c 
ATOM   6407 H HB3  . HIS A 1 385 ? -20.865 -27.599 -25.823 1.000 9.515  0 412  HIS A HB3  1 c 
ATOM   6408 H HD1  . HIS A 1 385 ? -22.096 -26.608 -28.432 0.000 13.740 0 412  HIS A HD1  1 c 
ATOM   6409 H HD2  . HIS A 1 385 ? -24.076 -28.071 -25.405 1.000 14.191 0 412  HIS A HD2  1 c 
ATOM   6410 H HE1  . HIS A 1 385 ? -24.408 -25.793 -28.581 1.000 15.215 0 412  HIS A HE1  1 c 
ATOM   6411 H HE2  . HIS A 1 385 ? -25.544 -26.722 -26.757 0.000 16.660 0 412  HIS A HE2  1 c 
ATOM   6412 N N    . LEU A 1 386 ? -19.197 -30.467 -26.417 1.000 7.417  0 413  LEU A N    1 ? 
ATOM   6413 C CA   . LEU A 1 386 ? -17.981 -31.016 -25.859 1.000 7.508  0 413  LEU A CA   1 ? 
ATOM   6414 C C    . LEU A 1 386 ? -16.870 -31.016 -26.902 1.000 7.502  0 413  LEU A C    1 ? 
ATOM   6415 O O    . LEU A 1 386 ? -15.720 -30.679 -26.617 1.000 7.193  0 413  LEU A O    1 ? 
ATOM   6416 C CB   . LEU A 1 386 ? -18.232 -32.450 -25.384 1.000 7.958  0 413  LEU A CB   1 ? 
ATOM   6417 C CG   . LEU A 1 386 ? -17.057 -33.160 -24.710 1.000 8.103  0 413  LEU A CG   1 ? 
ATOM   6418 C CD1  . LEU A 1 386 ? -16.625 -32.539 -23.403 1.000 9.997  0 413  LEU A CD1  1 ? 
ATOM   6419 C CD2  . LEU A 1 386 ? -17.336 -34.654 -24.519 1.000 10.290 0 413  LEU A CD2  1 ? 
ATOM   6420 H H    . LEU A 1 386 ? -19.958 -30.973 -26.424 1.000 7.464  0 413  LEU A H    1 c 
ATOM   6421 H HA   . LEU A 1 386 ? -17.704 -30.456 -25.090 1.000 7.589  0 413  LEU A HA   1 c 
ATOM   6422 H HB2  . LEU A 1 386 ? -18.987 -32.435 -24.752 1.000 7.885  0 413  LEU A HB2  1 c 
ATOM   6423 H HB3  . LEU A 1 386 ? -18.511 -32.986 -26.161 1.000 7.883  0 413  LEU A HB3  1 c 
ATOM   6424 H HG   . LEU A 1 386 ? -16.281 -33.095 -25.325 1.000 8.781  0 413  LEU A HG   1 c 
ATOM   6425 H HD11 . LEU A 1 386 ? -16.321 -31.629 -23.560 1.000 9.375  0 413  LEU A HD11 1 c 
ATOM   6426 H HD12 . LEU A 1 386 ? -15.899 -33.060 -23.020 1.000 9.374  0 413  LEU A HD12 1 c 
ATOM   6427 H HD13 . LEU A 1 386 ? -17.375 -32.527 -22.785 1.000 9.385  0 413  LEU A HD13 1 c 
ATOM   6428 H HD21 . LEU A 1 386 ? -17.505 -35.066 -25.383 1.000 9.594  0 413  LEU A HD21 1 c 
ATOM   6429 H HD22 . LEU A 1 386 ? -18.115 -34.769 -23.949 1.000 9.600  0 413  LEU A HD22 1 c 
ATOM   6430 H HD23 . LEU A 1 386 ? -16.566 -35.078 -24.104 1.000 9.593  0 413  LEU A HD23 1 c 
ATOM   6431 N N    . LEU A 1 387 ? -17.200 -31.439 -28.128 1.000 7.398  0 414  LEU A N    1 ? 
ATOM   6432 C CA   . LEU A 1 387 ? -16.215 -31.468 -29.213 1.000 6.928  0 414  LEU A CA   1 ? 
ATOM   6433 C C    . LEU A 1 387 ? -15.716 -30.057 -29.529 1.000 7.811  0 414  LEU A C    1 ? 
ATOM   6434 O O    . LEU A 1 387 ? -14.529 -29.883 -29.810 1.000 7.853  0 414  LEU A O    1 ? 
ATOM   6435 C CB   . LEU A 1 387 ? -16.788 -32.101 -30.475 1.000 7.746  0 414  LEU A CB   1 ? 
ATOM   6436 C CG   . LEU A 1 387 ? -17.194 -33.571 -30.346 1.000 8.726  0 414  LEU A CG   1 ? 
ATOM   6437 C CD1  . LEU A 1 387 ? -17.740 -34.078 -31.676 1.000 8.687  0 414  LEU A CD1  1 ? 
ATOM   6438 C CD2  . LEU A 1 387 ? -16.017 -34.400 -29.931 1.000 9.935  0 414  LEU A CD2  1 ? 
ATOM   6439 H H    . LEU A 1 387 ? -18.053 -31.720 -28.297 1.000 7.336  0 414  LEU A H    1 c 
ATOM   6440 H HA   . LEU A 1 387 ? -15.441 -32.004 -28.908 1.000 7.345  0 414  LEU A HA   1 c 
ATOM   6441 H HB2  . LEU A 1 387 ? -17.579 -31.582 -30.748 1.000 7.761  0 414  LEU A HB2  1 c 
ATOM   6442 H HB3  . LEU A 1 387 ? -16.115 -32.027 -31.190 1.000 7.772  0 414  LEU A HB3  1 c 
ATOM   6443 H HG   . LEU A 1 387 ? -17.901 -33.649 -29.657 1.000 8.724  0 414  LEU A HG   1 c 
ATOM   6444 H HD11 . LEU A 1 387 ? -18.559 -33.602 -31.894 1.000 8.700  0 414  LEU A HD11 1 c 
ATOM   6445 H HD12 . LEU A 1 387 ? -17.928 -35.029 -31.610 1.000 8.705  0 414  LEU A HD12 1 c 
ATOM   6446 H HD13 . LEU A 1 387 ? -17.083 -33.927 -32.376 1.000 8.700  0 414  LEU A HD13 1 c 
ATOM   6447 H HD21 . LEU A 1 387 ? -15.823 -34.243 -28.992 1.000 9.517  0 414  LEU A HD21 1 c 
ATOM   6448 H HD22 . LEU A 1 387 ? -15.242 -34.156 -30.466 1.000 9.534  0 414  LEU A HD22 1 c 
ATOM   6449 H HD23 . LEU A 1 387 ? -16.218 -35.341 -30.065 1.000 9.534  0 414  LEU A HD23 1 c 
ATOM   6450 N N    . ARG A 1 388 ? -16.603 -29.065 -29.527 1.000 7.385  0 415  ARG A N    1 ? 
ATOM   6451 C CA   . ARG A 1 388 ? -16.210 -27.702 -29.839 1.000 7.817  0 415  ARG A CA   1 ? 
ATOM   6452 C C    . ARG A 1 388 ? -15.283 -27.155 -28.761 1.000 7.437  0 415  ARG A C    1 ? 
ATOM   6453 O O    . ARG A 1 388 ? -14.356 -26.386 -29.057 1.000 7.556  0 415  ARG A O    1 ? 
ATOM   6454 C CB   . ARG A 1 388 ? -17.429 -26.827 -30.072 1.000 8.755  0 415  ARG A CB   1 ? 
ATOM   6455 C CG   . ARG A 1 388 ? -17.083 -25.408 -30.469 1.000 10.852 0 415  ARG A CG   1 ? 
ATOM   6456 C CD   . ARG A 1 388 ? -18.221 -24.641 -31.170 1.000 13.210 0 415  ARG A CD   1 ? 
ATOM   6457 N NE   . ARG A 1 388 ? -19.396 -24.529 -30.314 1.000 15.929 0 415  ARG A NE   1 ? 
ATOM   6458 C CZ   . ARG A 1 388 ? -19.681 -23.492 -29.495 1.000 16.082 0 415  ARG A CZ   1 ? 
ATOM   6459 N NH1  . ARG A 1 388 ? -18.819 -22.504 -29.334 1.000 16.383 0 415  ARG A NH1  1 ? 
ATOM   6460 N NH2  . ARG A 1 388 ? -20.790 -23.502 -28.766 1.000 20.852 0 415  ARG A NH2  1 ? 
ATOM   6461 H H    . ARG A 1 388 ? -17.478 -29.240 -29.332 1.000 7.583  0 415  ARG A H    1 c 
ATOM   6462 H HA   . ARG A 1 388 ? -15.702 -27.723 -30.690 1.000 7.825  0 415  ARG A HA   1 c 
ATOM   6463 H HB2  . ARG A 1 388 ? -17.978 -27.229 -30.779 1.000 8.965  0 415  ARG A HB2  1 c 
ATOM   6464 H HB3  . ARG A 1 388 ? -17.967 -26.805 -29.252 1.000 8.972  0 415  ARG A HB3  1 c 
ATOM   6465 H HG2  . ARG A 1 388 ? -16.820 -24.910 -29.664 1.000 10.774 0 415  ARG A HG2  1 c 
ATOM   6466 H HG3  . ARG A 1 388 ? -16.303 -25.428 -31.066 1.000 10.773 0 415  ARG A HG3  1 c 
ATOM   6467 H HD2  . ARG A 1 388 ? -17.909 -23.745 -31.414 1.000 13.252 0 415  ARG A HD2  1 c 
ATOM   6468 H HD3  . ARG A 1 388 ? -18.466 -25.109 -31.994 1.000 13.229 0 415  ARG A HD3  1 c 
ATOM   6469 H HE   . ARG A 1 388 ? -19.965 -25.188 -30.330 1.000 15.345 0 415  ARG A HE   1 c 
ATOM   6470 H HH11 . ARG A 1 388 ? -19.098 -21.667 -29.386 1.000 16.277 0 415  ARG A HH11 1 c 
ATOM   6471 H HH12 . ARG A 1 388 ? -17.969 -22.683 -29.175 1.000 16.236 0 415  ARG A HH12 1 c 
ATOM   6472 H HH21 . ARG A 1 388 ? -20.978 -22.813 -28.244 1.000 19.207 0 415  ARG A HH21 1 c 
ATOM   6473 H HH22 . ARG A 1 388 ? -21.338 -24.195 -28.802 1.000 19.176 0 415  ARG A HH22 1 c 
ATOM   6474 N N    . PHE A 1 389 ? -15.506 -27.496 -27.495 1.000 7.259  0 416  PHE A N    1 ? 
ATOM   6475 C CA   . PHE A 1 389 ? -14.615 -27.161 -26.401 1.000 6.249  0 416  PHE A CA   1 ? 
ATOM   6476 C C    . PHE A 1 389 ? -13.214 -27.666 -26.712 1.000 7.215  0 416  PHE A C    1 ? 
ATOM   6477 O O    . PHE A 1 389 ? -12.256 -26.890 -26.629 1.000 7.449  0 416  PHE A O    1 ? 
ATOM   6478 C CB   . PHE A 1 389 ? -15.231 -27.704 -25.103 1.000 6.745  0 416  PHE A CB   1 ? 
ATOM   6479 C CG   . PHE A 1 389 ? -14.362 -27.591 -23.879 1.000 6.849  0 416  PHE A CG   1 ? 
ATOM   6480 C CD1  . PHE A 1 389 ? -14.192 -26.361 -23.234 1.000 7.030  0 416  PHE A CD1  1 ? 
ATOM   6481 C CD2  . PHE A 1 389 ? -13.752 -28.697 -23.360 1.000 8.270  0 416  PHE A CD2  1 ? 
ATOM   6482 C CE1  . PHE A 1 389 ? -13.431 -26.272 -22.089 1.000 7.642  0 416  PHE A CE1  1 ? 
ATOM   6483 C CE2  . PHE A 1 389 ? -12.963 -28.615 -22.236 1.000 8.527  0 416  PHE A CE2  1 ? 
ATOM   6484 C CZ   . PHE A 1 389 ? -12.844 -27.412 -21.580 1.000 7.924  0 416  PHE A CZ   1 ? 
ATOM   6485 H H    . PHE A 1 389 ? -16.268 -27.961 -27.301 1.000 7.057  0 416  PHE A H    1 c 
ATOM   6486 H HA   . PHE A 1 389 ? -14.577 -26.171 -26.332 1.000 6.720  0 416  PHE A HA   1 c 
ATOM   6487 H HB2  . PHE A 1 389 ? -16.071 -27.222 -24.936 1.000 6.657  0 416  PHE A HB2  1 c 
ATOM   6488 H HB3  . PHE A 1 389 ? -15.458 -28.649 -25.240 1.000 6.675  0 416  PHE A HB3  1 c 
ATOM   6489 H HD1  . PHE A 1 389 ? -14.628 -25.594 -23.569 1.000 7.164  0 416  PHE A HD1  1 c 
ATOM   6490 H HD2  . PHE A 1 389 ? -13.860 -29.529 -23.791 1.000 7.942  0 416  PHE A HD2  1 c 
ATOM   6491 H HE1  . PHE A 1 389 ? -13.321 -25.442 -21.652 1.000 7.562  0 416  PHE A HE1  1 c 
ATOM   6492 H HE2  . PHE A 1 389 ? -12.557 -29.391 -21.884 1.000 8.292  0 416  PHE A HE2  1 c 
ATOM   6493 H HZ   . PHE A 1 389 ? -12.290 -27.350 -20.818 1.000 7.981  0 416  PHE A HZ   1 c 
ATOM   6494 N N    . TYR A 1 390 ? -13.069 -28.982 -26.954 1.000 6.519  0 417  TYR A N    1 ? 
ATOM   6495 C CA   . TYR A 1 390 ? -11.747 -29.491 -27.273 1.000 6.529  0 417  TYR A CA   1 ? 
ATOM   6496 C C    . TYR A 1 390 ? -11.158 -28.865 -28.541 1.000 6.205  0 417  TYR A C    1 ? 
ATOM   6497 O O    . TYR A 1 390 ? -9.950  -28.623 -28.595 1.000 7.629  0 417  TYR A O    1 ? 
ATOM   6498 C CB   . TYR A 1 390 ? -11.777 -31.025 -27.354 1.000 7.062  0 417  TYR A CB   1 ? 
ATOM   6499 C CG   . TYR A 1 390 ? -11.736 -31.660 -25.979 1.000 6.900  0 417  TYR A CG   1 ? 
ATOM   6500 C CD1  . TYR A 1 390 ? -10.526 -31.871 -25.363 1.000 7.511  0 417  TYR A CD1  1 ? 
ATOM   6501 C CD2  . TYR A 1 390 ? -12.877 -32.022 -25.301 1.000 7.162  0 417  TYR A CD2  1 ? 
ATOM   6502 C CE1  . TYR A 1 390 ? -10.423 -32.426 -24.099 1.000 7.833  0 417  TYR A CE1  1 ? 
ATOM   6503 C CE2  . TYR A 1 390 ? -12.798 -32.562 -24.029 1.000 7.383  0 417  TYR A CE2  1 ? 
ATOM   6504 C CZ   . TYR A 1 390 ? -11.573 -32.735 -23.407 1.000 7.550  0 417  TYR A CZ   1 ? 
ATOM   6505 O OH   . TYR A 1 390 ? -11.517 -33.353 -22.168 1.000 8.522  0 417  TYR A OH   1 ? 
ATOM   6506 H H    . TYR A 1 390 ? -13.784 -29.550 -26.919 1.000 6.686  0 417  TYR A H    1 c 
ATOM   6507 H HA   . TYR A 1 390 ? -11.148 -29.248 -26.517 1.000 6.569  0 417  TYR A HA   1 c 
ATOM   6508 H HB2  . TYR A 1 390 ? -12.598 -31.304 -27.817 1.000 6.899  0 417  TYR A HB2  1 c 
ATOM   6509 H HB3  . TYR A 1 390 ? -11.003 -31.331 -27.876 1.000 6.897  0 417  TYR A HB3  1 c 
ATOM   6510 H HD1  . TYR A 1 390 ? -9.735  -31.623 -25.815 1.000 7.435  0 417  TYR A HD1  1 c 
ATOM   6511 H HD2  . TYR A 1 390 ? -13.721 -31.873 -25.693 1.000 7.161  0 417  TYR A HD2  1 c 
ATOM   6512 H HE1  . TYR A 1 390 ? -9.579  -32.555 -23.701 1.000 7.691  0 417  TYR A HE1  1 c 
ATOM   6513 H HE2  . TYR A 1 390 ? -13.587 -32.806 -23.576 1.000 7.388  0 417  TYR A HE2  1 c 
ATOM   6514 H HH   . TYR A 1 390 ? -11.483 -32.762 -21.547 0.000 8.530  0 417  TYR A HH   1 c 
ATOM   6515 N N    . ASP A 1 391 ? -11.965 -28.606 -29.552 1.000 6.473  0 418  ASP A N    1 ? 
ATOM   6516 C CA   . ASP A 1 391 ? -11.482 -28.014 -30.792 1.000 6.513  0 418  ASP A CA   1 ? 
ATOM   6517 C C    . ASP A 1 391 ? -10.833 -26.663 -30.508 1.000 6.454  0 418  ASP A C    1 ? 
ATOM   6518 O O    . ASP A 1 391 ? -9.775  -26.318 -31.086 1.000 7.013  0 418  ASP A O    1 ? 
ATOM   6519 C CB   . ASP A 1 391 ? -12.601 -27.886 -31.810 1.000 7.135  0 418  ASP A CB   1 ? 
ATOM   6520 C CG   . ASP A 1 391 ? -12.164 -27.408 -33.168 1.000 7.831  0 418  ASP A CG   1 ? 
ATOM   6521 O OD1  . ASP A 1 391 ? -11.206 -27.998 -33.726 1.000 7.685  0 418  ASP A OD1  1 ? 
ATOM   6522 O OD2  . ASP A 1 391 ? -12.763 -26.441 -33.681 1.000 8.293  0 418  ASP A OD2  1 ? 
ATOM   6523 H H    . ASP A 1 391 ? -12.853 -28.808 -29.479 1.000 6.423  0 418  ASP A H    1 c 
ATOM   6524 H HA   . ASP A 1 391 ? -10.797 -28.608 -31.169 1.000 6.632  0 418  ASP A HA   1 c 
ATOM   6525 H HB2  . ASP A 1 391 ? -13.031 -28.760 -31.917 1.000 7.142  0 418  ASP A HB2  1 c 
ATOM   6526 H HB3  . ASP A 1 391 ? -13.271 -27.260 -31.464 1.000 7.147  0 418  ASP A HB3  1 c 
ATOM   6527 N N    . GLY A 1 392 ? -11.485 -25.831 -29.689 1.000 7.086  0 419  GLY A N    1 ? 
ATOM   6528 C CA   . GLY A 1 392 ? -10.944 -24.490 -29.445 1.000 6.695  0 419  GLY A CA   1 ? 
ATOM   6529 C C    . GLY A 1 392 ? -9.624  -24.580 -28.673 1.000 7.092  0 419  GLY A C    1 ? 
ATOM   6530 O O    . GLY A 1 392 ? -8.696  -23.799 -28.923 1.000 7.406  0 419  GLY A O    1 ? 
ATOM   6531 H H    . GLY A 1 392 ? -12.264 -26.086 -29.285 1.000 6.838  0 419  GLY A H    1 c 
ATOM   6532 H HA2  . GLY A 1 392 ? -10.796 -24.035 -30.307 1.000 6.875  0 419  GLY A HA2  1 c 
ATOM   6533 H HA3  . GLY A 1 392 ? -11.597 -23.965 -28.928 1.000 6.894  0 419  GLY A HA3  1 c 
ATOM   6534 N N    . ILE A 1 393 ? -9.497  -25.529 -27.748 1.000 7.553  0 420  ILE A N    1 ? 
ATOM   6535 C CA   . ILE A 1 393 ? -8.258  -25.716 -27.014 1.000 7.388  0 420  ILE A CA   1 ? 
ATOM   6536 C C    . ILE A 1 393 ? -7.163  -26.167 -27.984 1.000 6.957  0 420  ILE A C    1 ? 
ATOM   6537 O O    . ILE A 1 393 ? -6.016  -25.684 -27.920 1.000 7.570  0 420  ILE A O    1 ? 
ATOM   6538 C CB   . ILE A 1 393 ? -8.472  -26.701 -25.851 1.000 7.662  0 420  ILE A CB   1 ? 
ATOM   6539 C CG1  . ILE A 1 393 ? -9.452  -26.113 -24.831 1.000 8.229  0 420  ILE A CG1  1 ? 
ATOM   6540 C CG2  . ILE A 1 393 ? -7.152  -27.102 -25.213 1.000 8.025  0 420  ILE A CG2  1 ? 
ATOM   6541 C CD1  . ILE A 1 393 ? -9.957  -27.117 -23.781 1.000 9.868  0 420  ILE A CD1  1 ? 
ATOM   6542 H H    . ILE A 1 393 ? -10.204 -26.080 -27.568 1.000 7.413  0 420  ILE A H    1 c 
ATOM   6543 H HA   . ILE A 1 393 ? -7.996  -24.854 -26.636 1.000 7.386  0 420  ILE A HA   1 c 
ATOM   6544 H HB   . ILE A 1 393 ? -8.881  -27.509 -26.220 1.000 7.777  0 420  ILE A HB   1 c 
ATOM   6545 H HG12 . ILE A 1 393 ? -9.012  -25.372 -24.367 1.000 8.434  0 420  ILE A HG12 1 c 
ATOM   6546 H HG13 . ILE A 1 393 ? -10.224 -25.748 -25.309 1.000 8.419  0 420  ILE A HG13 1 c 
ATOM   6547 H HG21 . ILE A 1 393 ? -7.321  -27.639 -24.421 1.000 7.933  0 420  ILE A HG21 1 c 
ATOM   6548 H HG22 . ILE A 1 393 ? -6.656  -26.304 -24.962 1.000 7.919  0 420  ILE A HG22 1 c 
ATOM   6549 H HG23 . ILE A 1 393 ? -6.627  -27.622 -25.845 1.000 7.915  0 420  ILE A HG23 1 c 
ATOM   6550 H HD11 . ILE A 1 393 ? -10.347 -27.891 -24.230 1.000 9.352  0 420  ILE A HD11 1 c 
ATOM   6551 H HD12 . ILE A 1 393 ? -10.636 -26.690 -23.226 1.000 9.346  0 420  ILE A HD12 1 c 
ATOM   6552 H HD13 . ILE A 1 393 ? -9.216  -27.409 -23.218 1.000 9.339  0 420  ILE A HD13 1 c 
ATOM   6553 N N    . CYS A 1 394 ? -7.494  -27.113 -28.877 1.000 6.833  0 421  CYS A N    1 ? 
ATOM   6554 C CA   . CYS A 1 394 ? -6.501  -27.530 -29.867 1.000 7.675  0 421  CYS A CA   1 ? 
ATOM   6555 C C    . CYS A 1 394 ? -6.088  -26.386 -30.785 1.000 7.717  0 421  CYS A C    1 ? 
ATOM   6556 O O    . CYS A 1 394 ? -4.917  -26.257 -31.148 1.000 8.226  0 421  CYS A O    1 ? 
ATOM   6557 C CB   . CYS A 1 394 ? -7.015  -28.705 -30.696 1.000 7.958  0 421  CYS A CB   1 ? 
ATOM   6558 S SG   . CYS A 1 394 ? -7.245  -30.266 -29.808 1.000 8.694  0 421  CYS A SG   1 ? 
ATOM   6559 H H    . CYS A 1 394 ? -8.321  -27.500 -28.871 1.000 7.054  0 421  CYS A H    1 c 
ATOM   6560 H HA   . CYS A 1 394 ? -5.696  -27.837 -29.376 1.000 7.558  0 421  CYS A HA   1 c 
ATOM   6561 H HB2  . CYS A 1 394 ? -7.878  -28.453 -31.091 1.000 8.022  0 421  CYS A HB2  1 c 
ATOM   6562 H HB3  . CYS A 1 394 ? -6.387  -28.867 -31.435 1.000 8.021  0 421  CYS A HB3  1 c 
ATOM   6563 H HG   . CYS A 1 394 ? -7.642  -30.925 -30.745 0.000 8.700  0 421  CYS A HG   1 c 
ATOM   6564 N N    . LYS A 1 395 ? -7.035  -25.553 -31.216 1.000 7.311  0 422  LYS A N    1 ? 
ATOM   6565 C CA   . LYS A 1 395 ? -6.686  -24.438 -32.072 1.000 7.589  0 422  LYS A CA   1 ? 
ATOM   6566 C C    . LYS A 1 395 ? -5.853  -23.387 -31.334 1.000 8.564  0 422  LYS A C    1 ? 
ATOM   6567 O O    . LYS A 1 395 ? -4.936  -22.822 -31.951 1.000 8.907  0 422  LYS A O    1 ? 
ATOM   6568 C CB   . LYS A 1 395 ? -7.935  -23.876 -32.727 1.000 8.745  0 422  LYS A CB   1 ? 
ATOM   6569 C CG   . LYS A 1 395 ? -7.729  -22.690 -33.646 1.000 11.447 0 422  LYS A CG   1 ? 
ATOM   6570 C CD   . LYS A 1 395 ? -6.985  -23.039 -34.926 1.000 13.738 0 422  LYS A CD   1 ? 
ATOM   6571 C CE   . LYS A 1 395 ? -7.037  -21.756 -35.762 1.000 19.819 0 422  LYS A CE   1 ? 
ATOM   6572 N NZ   . LYS A 1 395 ? -6.321  -21.887 -37.024 1.000 26.297 0 422  LYS A NZ   1 ? 
ATOM   6573 H H    . LYS A 1 395 ? -7.908  -25.682 -30.978 1.000 7.474  0 422  LYS A H    1 c 
ATOM   6574 H HA   . LYS A 1 395 ? -6.125  -24.793 -32.808 1.000 7.936  0 422  LYS A HA   1 c 
ATOM   6575 H HB2  . LYS A 1 395 ? -8.359  -24.593 -33.246 1.000 9.012  0 422  LYS A HB2  1 c 
ATOM   6576 H HB3  . LYS A 1 395 ? -8.563  -23.615 -32.021 1.000 9.023  0 422  LYS A HB3  1 c 
ATOM   6577 H HG2  . LYS A 1 395 ? -8.608  -22.318 -33.877 1.000 11.299 0 422  LYS A HG2  1 c 
ATOM   6578 H HG3  . LYS A 1 395 ? -7.228  -21.998 -33.163 1.000 11.251 0 422  LYS A HG3  1 c 
ATOM   6579 H HD2  . LYS A 1 395 ? -6.053  -23.279 -34.732 1.000 14.329 0 422  LYS A HD2  1 c 
ATOM   6580 H HD3  . LYS A 1 395 ? -7.437  -23.770 -35.402 1.000 14.329 0 422  LYS A HD3  1 c 
ATOM   6581 H HE2  . LYS A 1 395 ? -7.965  -21.529 -35.951 1.000 19.374 0 422  LYS A HE2  1 c 
ATOM   6582 H HE3  . LYS A 1 395 ? -6.645  -21.023 -35.254 1.000 19.376 0 422  LYS A HE3  1 c 
ATOM   6583 H HZ1  . LYS A 1 395 ? -6.689  -22.552 -37.517 1.000 24.098 0 422  LYS A HZ1  1 c 
ATOM   6584 H HZ2  . LYS A 1 395 ? -5.451  -22.082 -36.864 1.000 24.098 0 422  LYS A HZ2  1 c 
ATOM   6585 H HZ3  . LYS A 1 395 ? -6.372  -21.110 -37.487 1.000 24.098 0 422  LYS A HZ3  1 c 
ATOM   6586 N N    . TRP A 1 396 ? -6.180  -23.115 -30.070 1.000 7.937  0 423  TRP A N    1 ? 
ATOM   6587 C CA   . TRP A 1 396 ? -5.350  -22.269 -29.213 1.000 7.643  0 423  TRP A CA   1 ? 
ATOM   6588 C C    . TRP A 1 396 ? -3.882  -22.671 -29.276 1.000 7.977  0 423  TRP A C    1 ? 
ATOM   6589 O O    . TRP A 1 396 ? -3.019  -21.826 -29.465 1.000 9.025  0 423  TRP A O    1 ? 
ATOM   6590 C CB   . TRP A 1 396 ? -5.912  -22.412 -27.801 1.000 7.972  0 423  TRP A CB   1 ? 
ATOM   6591 C CG   . TRP A 1 396 ? -5.220  -21.654 -26.700 1.000 7.634  0 423  TRP A CG   1 ? 
ATOM   6592 C CD1  . TRP A 1 396 ? -4.633  -20.417 -26.746 1.000 8.097  0 423  TRP A CD1  1 ? 
ATOM   6593 C CD2  . TRP A 1 396 ? -5.285  -22.009 -25.306 1.000 8.134  0 423  TRP A CD2  1 ? 
ATOM   6594 N NE1  . TRP A 1 396 ? -4.257  -20.039 -25.489 1.000 9.295  0 423  TRP A NE1  1 ? 
ATOM   6595 C CE2  . TRP A 1 396 ? -4.696  -20.965 -24.584 1.000 9.175  0 423  TRP A CE2  1 ? 
ATOM   6596 C CE3  . TRP A 1 396 ? -5.862  -23.085 -24.636 1.000 9.655  0 423  TRP A CE3  1 ? 
ATOM   6597 C CZ2  . TRP A 1 396 ? -4.623  -20.989 -23.194 1.000 9.984  0 423  TRP A CZ2  1 ? 
ATOM   6598 C CZ3  . TRP A 1 396 ? -5.788  -23.130 -23.268 1.000 10.376 0 423  TRP A CZ3  1 ? 
ATOM   6599 C CH2  . TRP A 1 396 ? -5.230  -22.065 -22.563 1.000 10.692 0 423  TRP A CH2  1 ? 
ATOM   6600 H H    . TRP A 1 396 ? -6.953  -23.462 -29.727 1.000 8.005  0 423  TRP A H    1 c 
ATOM   6601 H HA   . TRP A 1 396 ? -5.444  -21.322 -29.504 1.000 7.819  0 423  TRP A HA   1 c 
ATOM   6602 H HB2  . TRP A 1 396 ? -6.853  -22.138 -27.821 1.000 7.818  0 423  TRP A HB2  1 c 
ATOM   6603 H HB3  . TRP A 1 396 ? -5.909  -23.364 -27.567 1.000 7.816  0 423  TRP A HB3  1 c 
ATOM   6604 H HD1  . TRP A 1 396 ? -4.431  -19.936 -27.530 1.000 8.272  0 423  TRP A HD1  1 c 
ATOM   6605 H HE1  . TRP A 1 396 ? -3.843  -19.296 -25.290 1.000 8.959  0 423  TRP A HE1  1 c 
ATOM   6606 H HE3  . TRP A 1 396 ? -6.265  -23.787 -25.118 1.000 9.443  0 423  TRP A HE3  1 c 
ATOM   6607 H HZ2  . TRP A 1 396 ? -4.232  -20.283 -22.707 1.000 9.934  0 423  TRP A HZ2  1 c 
ATOM   6608 H HZ3  . TRP A 1 396 ? -6.173  -23.852 -22.800 1.000 10.244 0 423  TRP A HZ3  1 c 
ATOM   6609 H HH2  . TRP A 1 396 ? -5.172  -22.126 -21.626 1.000 10.392 0 423  TRP A HH2  1 c 
ATOM   6610 N N    . GLU A 1 397 ? -3.642  -23.973 -29.149 1.000 8.666  0 424  GLU A N    1 ? 
ATOM   6611 C CA   . GLU A 1 397 ? -2.280  -24.477 -29.134 1.000 9.775  0 424  GLU A CA   1 ? 
ATOM   6612 C C    . GLU A 1 397 ? -1.550  -24.243 -30.463 1.000 9.866  0 424  GLU A C    1 ? 
ATOM   6613 O O    . GLU A 1 397 ? -0.331  -24.068 -30.463 1.000 10.911 0 424  GLU A O    1 ? 
ATOM   6614 C CB   . GLU A 1 397 ? -2.386  -25.967 -28.871 1.000 10.516 0 424  GLU A CB   1 ? 
ATOM   6615 C CG   . GLU A 1 397 ? -1.078  -26.717 -28.858 1.000 11.109 0 424  GLU A CG   1 ? 
ATOM   6616 C CD   . GLU A 1 397 ? -1.342  -28.164 -28.507 1.000 11.322 0 424  GLU A CD   1 ? 
ATOM   6617 O OE1  . GLU A 1 397 ? -1.946  -28.975 -29.271 1.000 11.160 0 424  GLU A OE1  1 ? 
ATOM   6618 O OE2  . GLU A 1 397 ? -0.796  -28.498 -27.423 1.000 13.545 0 424  GLU A OE2  1 ? 
ATOM   6619 H H    . GLU A 1 397 ? -4.337  -24.561 -29.064 1.000 8.753  0 424  GLU A H    1 c 
ATOM   6620 H HA   . GLU A 1 397 ? -1.781  -24.035 -28.401 1.000 9.692  0 424  GLU A HA   1 c 
ATOM   6621 H HB2  . GLU A 1 397 ? -2.829  -26.100 -28.007 1.000 10.461 0 424  GLU A HB2  1 c 
ATOM   6622 H HB3  . GLU A 1 397 ? -2.956  -26.366 -29.560 1.000 10.450 0 424  GLU A HB3  1 c 
ATOM   6623 H HG2  . GLU A 1 397 ? -0.656  -26.671 -29.742 1.000 11.017 0 424  GLU A HG2  1 c 
ATOM   6624 H HG3  . GLU A 1 397 ? -0.473  -26.322 -28.194 1.000 11.043 0 424  GLU A HG3  1 c 
ATOM   6625 N N    . GLU A 1 398 ? -2.254  -24.208 -31.586 1.000 9.517  0 425  GLU A N    1 ? 
ATOM   6626 C CA   . GLU A 1 398 ? -1.609  -24.042 -32.890 1.000 9.798  0 425  GLU A CA   1 ? 
ATOM   6627 C C    . GLU A 1 398 ? -0.926  -22.685 -32.978 1.000 12.193 0 425  GLU A C    1 ? 
ATOM   6628 O O    . GLU A 1 398 ? -1.511  -21.635 -32.696 1.000 13.981 0 425  GLU A O    1 ? 
ATOM   6629 C CB   . GLU A 1 398 ? -2.568  -24.181 -34.085 1.000 9.580  0 425  GLU A CB   1 ? 
ATOM   6630 C CG   . GLU A 1 398 ? -3.199  -25.560 -34.213 1.000 9.810  0 425  GLU A CG   1 ? 
ATOM   6631 C CD   . GLU A 1 398 ? -4.126  -25.723 -35.404 1.000 9.754  0 425  GLU A CD   1 ? 
ATOM   6632 O OE1  . GLU A 1 398 ? -4.142  -24.858 -36.286 1.000 12.138 0 425  GLU A OE1  1 ? 
ATOM   6633 O OE2  . GLU A 1 398 ? -4.814  -26.756 -35.443 1.000 10.302 0 425  GLU A OE2  1 ? 
ATOM   6634 H H    . GLU A 1 398 ? -3.163  -24.299 -31.553 1.000 9.640  0 425  GLU A H    1 c 
ATOM   6635 H HA   . GLU A 1 398 ? -0.917  -24.747 -32.976 1.000 10.144 0 425  GLU A HA   1 c 
ATOM   6636 H HB2  . GLU A 1 398 ? -3.281  -23.514 -33.996 1.000 9.686  0 425  GLU A HB2  1 c 
ATOM   6637 H HB3  . GLU A 1 398 ? -2.075  -23.981 -34.908 1.000 9.706  0 425  GLU A HB3  1 c 
ATOM   6638 H HG2  . GLU A 1 398 ? -2.486  -26.231 -34.282 1.000 9.743  0 425  GLU A HG2  1 c 
ATOM   6639 H HG3  . GLU A 1 398 ? -3.707  -25.754 -33.398 1.000 9.736  0 425  GLU A HG3  1 c 
ATOM   6640 N N    . GLY A 1 399 ? 0.358   -22.716 -33.347 1.000 13.435 0 426  GLY A N    1 ? 
ATOM   6641 C CA   . GLY A 1 399 ? 1.056   -21.441 -33.466 1.000 15.184 0 426  GLY A CA   1 ? 
ATOM   6642 C C    . GLY A 1 399 ? 1.661   -20.955 -32.157 1.000 15.711 0 426  GLY A C    1 ? 
ATOM   6643 O O    . GLY A 1 399 ? 2.278   -19.886 -32.129 1.000 19.708 0 426  GLY A O    1 ? 
ATOM   6644 H H    . GLY A 1 399 ? 0.794   -23.500 -33.521 1.000 13.424 0 426  GLY A H    1 c 
ATOM   6645 H HA2  . GLY A 1 399 ? 1.775   -21.539 -34.134 1.000 14.856 0 426  GLY A HA2  1 c 
ATOM   6646 H HA3  . GLY A 1 399 ? 0.428   -20.761 -33.806 1.000 14.839 0 426  GLY A HA3  1 c 
ATOM   6647 N N    . SER A 1 400 ? 1.351   -21.588 -31.031 1.000 13.830 0 427  SER A N    1 ? 
ATOM   6648 C CA   . SER A 1 400 ? 1.745   -21.074 -29.734 1.000 13.482 0 427  SER A CA   1 ? 
ATOM   6649 C C    . SER A 1 400 ? 3.189   -21.416 -29.428 1.000 14.895 0 427  SER A C    1 ? 
ATOM   6650 O O    . SER A 1 400 ? 3.701   -22.431 -29.892 1.000 16.759 0 427  SER A O    1 ? 
ATOM   6651 C CB   . SER A 1 400 ? 0.891   -21.610 -28.627 1.000 13.327 0 427  SER A CB   1 ? 
ATOM   6652 O OG   . SER A 1 400 ? -0.447  -21.156 -28.706 1.000 12.230 0 427  SER A OG   1 ? 
ATOM   6653 H H    . SER A 1 400 ? 0.889   -22.376 -31.066 1.000 14.156 0 427  SER A H    1 c 
ATOM   6654 H HA   . SER A 1 400 ? 1.650   -20.089 -29.751 1.000 13.849 0 427  SER A HA   1 c 
ATOM   6655 H HB2  . SER A 1 400 ? 0.902   -22.585 -28.660 1.000 13.082 0 427  SER A HB2  1 c 
ATOM   6656 H HB3  . SER A 1 400 ? 1.271   -21.337 -27.770 1.000 13.100 0 427  SER A HB3  1 c 
ATOM   6657 H HG   . SER A 1 400 ? -0.881  -21.489 -28.059 0.000 12.240 0 427  SER A HG   1 c 
ATOM   6658 N N    . PRO A 1 401 ? 3.876   -20.569 -28.642 1.000 14.445 0 428  PRO A N    1 ? 
ATOM   6659 C CA   . PRO A 1 401 ? 5.284   -20.840 -28.334 1.000 16.533 0 428  PRO A CA   1 ? 
ATOM   6660 C C    . PRO A 1 401 ? 5.462   -21.915 -27.287 1.000 22.122 0 428  PRO A C    1 ? 
ATOM   6661 O O    . PRO A 1 401 ? 6.541   -22.469 -27.171 1.000 24.258 0 428  PRO A O    1 ? 
ATOM   6662 C CB   . PRO A 1 401 ? 5.764   -19.459 -27.879 1.000 17.302 0 428  PRO A CB   1 ? 
ATOM   6663 C CG   . PRO A 1 401 ? 4.552   -18.810 -27.286 1.000 17.433 0 428  PRO A CG   1 ? 
ATOM   6664 C CD   . PRO A 1 401 ? 3.426   -19.231 -28.222 1.000 16.246 0 428  PRO A CD   1 ? 
ATOM   6665 H HA   . PRO A 1 401 ? 5.757   -21.097 -29.166 1.000 17.126 0 428  PRO A HA   1 c 
ATOM   6666 H HB2  . PRO A 1 401 ? 6.482   -19.540 -27.208 1.000 17.182 0 428  PRO A HB2  1 c 
ATOM   6667 H HB3  . PRO A 1 401 ? 6.102   -18.936 -28.644 1.000 17.162 0 428  PRO A HB3  1 c 
ATOM   6668 H HG2  . PRO A 1 401 ? 4.390   -19.133 -26.375 1.000 17.219 0 428  PRO A HG2  1 c 
ATOM   6669 H HG3  . PRO A 1 401 ? 4.647   -17.835 -27.268 1.000 17.218 0 428  PRO A HG3  1 c 
ATOM   6670 H HD2  . PRO A 1 401 ? 2.566   -19.271 -27.751 1.000 16.004 0 428  PRO A HD2  1 c 
ATOM   6671 H HD3  . PRO A 1 401 ? 3.353   -18.620 -28.989 1.000 16.033 0 428  PRO A HD3  1 c 
ATOM   6672 N N    . THR A 1 402 ? 4.369   -22.215 -26.566 1.000 24.050 0 429  THR A N    1 ? 
ATOM   6673 C CA   . THR A 1 402 ? 4.358   -23.258 -25.556 1.000 27.793 0 429  THR A CA   1 ? 
ATOM   6674 C C    . THR A 1 402 ? 3.146   -24.153 -25.818 1.000 23.986 0 429  THR A C    1 ? 
ATOM   6675 O O    . THR A 1 402 ? 2.100   -23.662 -26.219 1.000 19.982 0 429  THR A O    1 ? 
ATOM   6676 C CB   . THR A 1 402 ? 4.393   -22.683 -24.126 1.000 34.933 0 429  THR A CB   1 ? 
ATOM   6677 O OG1  . THR A 1 402 ? 3.574   -23.485 -23.285 1.000 45.063 0 429  THR A OG1  1 ? 
ATOM   6678 C CG2  . THR A 1 402 ? 3.886   -21.259 -23.931 1.000 30.834 0 429  THR A CG2  1 ? 
ATOM   6679 H H    . THR A 1 402 ? 3.601   -21.739 -26.702 1.000 24.153 0 429  THR A H    1 c 
ATOM   6680 H HA   . THR A 1 402 ? 5.167   -23.795 -25.678 1.000 27.312 0 429  THR A HA   1 c 
ATOM   6681 H HB   . THR A 1 402 ? 5.322   -22.721 -23.795 1.000 34.432 0 429  THR A HB   1 c 
ATOM   6682 H HG1  . THR A 1 402 ? 2.762   -23.481 -23.582 0.000 44.950 0 429  THR A HG1  1 c 
ATOM   6683 H HG21 . THR A 1 402 ? 4.098   -20.960 -23.031 1.000 31.883 0 429  THR A HG21 1 c 
ATOM   6684 H HG22 . THR A 1 402 ? 2.923   -21.240 -24.058 1.000 31.693 0 429  THR A HG22 1 c 
ATOM   6685 H HG23 . THR A 1 402 ? 4.310   -20.668 -24.575 1.000 31.731 0 429  THR A HG23 1 c 
ATOM   6686 N N    . PRO A 1 403 ? 3.284   -25.490 -25.670 1.000 21.993 0 430  PRO A N    1 ? 
ATOM   6687 C CA   . PRO A 1 403 ? 2.184   -26.429 -25.933 1.000 19.620 0 430  PRO A CA   1 ? 
ATOM   6688 C C    . PRO A 1 403 ? 1.148   -26.378 -24.827 1.000 15.840 0 430  PRO A C    1 ? 
ATOM   6689 O O    . PRO A 1 403 ? 1.396   -25.900 -23.715 1.000 16.087 0 430  PRO A O    1 ? 
ATOM   6690 C CB   . PRO A 1 403 ? 2.801   -27.824 -26.003 1.000 22.626 0 430  PRO A CB   1 ? 
ATOM   6691 C CG   . PRO A 1 403 ? 4.299   -27.554 -25.882 1.000 27.436 0 430  PRO A CG   1 ? 
ATOM   6692 C CD   . PRO A 1 403 ? 4.507   -26.198 -25.254 1.000 25.085 0 430  PRO A CD   1 ? 
ATOM   6693 H HA   . PRO A 1 403 ? 1.765   -26.207 -26.802 1.000 19.730 0 430  PRO A HA   1 c 
ATOM   6694 H HB2  . PRO A 1 403 ? 2.483   -28.392 -25.262 1.000 22.832 0 430  PRO A HB2  1 c 
ATOM   6695 H HB3  . PRO A 1 403 ? 2.589   -28.262 -26.861 1.000 22.873 0 430  PRO A HB3  1 c 
ATOM   6696 H HG2  . PRO A 1 403 ? 4.720   -28.246 -25.330 1.000 25.737 0 430  PRO A HG2  1 c 
ATOM   6697 H HG3  . PRO A 1 403 ? 4.717   -27.579 -26.768 1.000 25.737 0 430  PRO A HG3  1 c 
ATOM   6698 H HD2  . PRO A 1 403 ? 4.570   -26.264 -24.276 1.000 24.890 0 430  PRO A HD2  1 c 
ATOM   6699 H HD3  . PRO A 1 403 ? 5.315   -25.768 -25.608 1.000 24.877 0 430  PRO A HD3  1 c 
ATOM   6700 N N    . VAL A 1 404 ? -0.055  -26.863 -25.175 1.000 12.036 0 431  VAL A N    1 ? 
ATOM   6701 C CA   . VAL A 1 404 ? -1.163  -26.911 -24.215 1.000 11.466 0 431  VAL A CA   1 ? 
ATOM   6702 C C    . VAL A 1 404 ? -1.450  -28.344 -23.793 1.000 10.889 0 431  VAL A C    1 ? 
ATOM   6703 O O    . VAL A 1 404 ? -1.530  -28.677 -22.612 1.000 11.131 0 431  VAL A O    1 ? 
ATOM   6704 C CB   . VAL A 1 404 ? -2.402  -26.236 -24.832 1.000 11.989 0 431  VAL A CB   1 ? 
ATOM   6705 C CG1  . VAL A 1 404 ? -3.619  -26.397 -23.913 1.000 11.700 0 431  VAL A CG1  1 ? 
ATOM   6706 C CG2  . VAL A 1 404 ? -2.125  -24.762 -25.111 1.000 13.355 0 431  VAL A CG2  1 ? 
ATOM   6707 H H    . VAL A 1 404 ? -0.192  -27.171 -26.024 1.000 12.767 0 431  VAL A H    1 c 
ATOM   6708 H HA   . VAL A 1 404 ? -0.905  -26.405 -23.420 1.000 11.604 0 431  VAL A HA   1 c 
ATOM   6709 H HB   . VAL A 1 404 ? -2.592  -26.688 -25.687 1.000 12.077 0 431  VAL A HB   1 c 
ATOM   6710 H HG11 . VAL A 1 404 ? -3.367  -26.180 -22.999 1.000 11.785 0 431  VAL A HG11 1 c 
ATOM   6711 H HG12 . VAL A 1 404 ? -3.940  -27.314 -23.951 1.000 11.781 0 431  VAL A HG12 1 c 
ATOM   6712 H HG13 . VAL A 1 404 ? -4.326  -25.796 -24.203 1.000 11.790 0 431  VAL A HG13 1 c 
ATOM   6713 H HG21 . VAL A 1 404 ? -2.932  -24.338 -25.448 1.000 12.926 0 431  VAL A HG21 1 c 
ATOM   6714 H HG22 . VAL A 1 404 ? -1.419  -24.684 -25.775 1.000 12.929 0 431  VAL A HG22 1 c 
ATOM   6715 H HG23 . VAL A 1 404 ? -1.847  -24.323 -24.290 1.000 12.928 0 431  VAL A HG23 1 c 
ATOM   6716 N N    . LEU A 1 405 ? -1.714  -29.216 -24.753 1.000 11.053 0 432  LEU A N    1 ? 
ATOM   6717 C CA   . LEU A 1 405 ? -2.170  -30.559 -24.474 1.000 10.855 0 432  LEU A CA   1 ? 
ATOM   6718 C C    . LEU A 1 405 ? -1.006  -31.472 -24.126 1.000 11.664 0 432  LEU A C    1 ? 
ATOM   6719 O O    . LEU A 1 405 ? 0.082   -31.329 -24.654 1.000 14.197 0 432  LEU A O    1 ? 
ATOM   6720 C CB   . LEU A 1 405 ? -2.957  -31.102 -25.666 1.000 11.121 0 432  LEU A CB   1 ? 
ATOM   6721 C CG   . LEU A 1 405 ? -4.264  -30.344 -25.918 1.000 13.593 0 432  LEU A CG   1 ? 
ATOM   6722 C CD1  . LEU A 1 405 ? -4.796  -30.496 -27.273 1.000 17.080 0 432  LEU A CD1  1 ? 
ATOM   6723 C CD2  . LEU A 1 405 ? -5.319  -30.716 -24.897 1.000 13.365 0 432  LEU A CD2  1 ? 
ATOM   6724 H H    . LEU A 1 405 ? -1.609  -28.963 -25.625 1.000 10.997 0 432  LEU A H    1 c 
ATOM   6725 H HA   . LEU A 1 405 ? -2.773  -30.518 -23.689 1.000 11.107 0 432  LEU A HA   1 c 
ATOM   6726 H HB2  . LEU A 1 405 ? -2.392  -31.036 -26.471 1.000 11.597 0 432  LEU A HB2  1 c 
ATOM   6727 H HB3  . LEU A 1 405 ? -3.168  -32.049 -25.498 1.000 11.580 0 432  LEU A HB3  1 c 
ATOM   6728 H HG   . LEU A 1 405 ? -4.075  -29.379 -25.793 1.000 13.638 0 432  LEU A HG   1 c 
ATOM   6729 H HD11 . LEU A 1 405 ? -4.139  -30.181 -27.917 1.000 15.907 0 432  LEU A HD11 1 c 
ATOM   6730 H HD12 . LEU A 1 405 ? -5.611  -29.975 -27.363 1.000 15.847 0 432  LEU A HD12 1 c 
ATOM   6731 H HD13 . LEU A 1 405 ? -4.990  -31.432 -27.443 1.000 15.904 0 432  LEU A HD13 1 c 
ATOM   6732 H HD21 . LEU A 1 405 ? -5.019  -30.458 -24.010 1.000 13.380 0 432  LEU A HD21 1 c 
ATOM   6733 H HD22 . LEU A 1 405 ? -5.469  -31.676 -24.921 1.000 13.426 0 432  LEU A HD22 1 c 
ATOM   6734 H HD23 . LEU A 1 405 ? -6.149  -30.255 -25.104 1.000 13.452 0 432  LEU A HD23 1 c 
ATOM   6735 N N    . HIS A 1 406 ? -1.332  -32.493 -23.336 1.000 10.644 0 433  HIS A N    1 ? 
ATOM   6736 C CA   . HIS A 1 406 ? -0.410  -33.581 -23.002 1.000 11.450 0 433  HIS A CA   1 ? 
ATOM   6737 C C    . HIS A 1 406 ? -1.252  -34.789 -22.639 1.000 11.739 0 433  HIS A C    1 ? 
ATOM   6738 O O    . HIS A 1 406 ? -2.473  -34.755 -22.552 1.000 12.047 0 433  HIS A O    1 ? 
ATOM   6739 C CB   . HIS A 1 406 ? 0.592   -33.174 -21.900 1.000 11.748 0 433  HIS A CB   1 ? 
ATOM   6740 C CG   . HIS A 1 406 ? 0.010   -32.788 -20.581 1.000 12.155 0 433  HIS A CG   1 ? 
ATOM   6741 N ND1  . HIS A 1 406 ? -0.657  -33.658 -19.752 1.000 12.170 0 433  HIS A ND1  1 ? 
ATOM   6742 C CD2  . HIS A 1 406 ? -0.037  -31.577 -19.981 1.000 12.684 0 433  HIS A CD2  1 ? 
ATOM   6743 C CE1  . HIS A 1 406 ? -0.999  -32.996 -18.642 1.000 11.498 0 433  HIS A CE1  1 ? 
ATOM   6744 N NE2  . HIS A 1 406 ? -0.659  -31.734 -18.777 1.000 11.831 0 433  HIS A NE2  1 ? 
ATOM   6745 H H    . HIS A 1 406 ? -2.176  -32.521 -22.988 1.000 11.035 0 433  HIS A H    1 c 
ATOM   6746 H HA   . HIS A 1 406 ? 0.103   -33.802 -23.819 1.000 11.408 0 433  HIS A HA   1 c 
ATOM   6747 H HB2  . HIS A 1 406 ? 1.216   -33.918 -21.759 1.000 11.798 0 433  HIS A HB2  1 c 
ATOM   6748 H HB3  . HIS A 1 406 ? 1.127   -32.422 -22.234 1.000 11.872 0 433  HIS A HB3  1 c 
ATOM   6749 H HD1  . HIS A 1 406 ? -0.803  -34.511 -19.919 0.000 12.160 0 433  HIS A HD1  1 c 
ATOM   6750 H HD2  . HIS A 1 406 ? 0.333   -30.779 -20.304 1.000 12.353 0 433  HIS A HD2  1 c 
ATOM   6751 H HE1  . HIS A 1 406 ? -1.478  -33.362 -17.918 1.000 11.751 0 433  HIS A HE1  1 c 
ATOM   6752 H HE2  . HIS A 1 406 ? -0.783  -31.106 -18.177 0.000 11.840 0 433  HIS A HE2  1 c 
ATOM   6753 N N    . VAL A 1 407 ? -0.579  -35.944 -22.408 1.000 11.711 0 434  VAL A N    1 ? 
ATOM   6754 C CA   . VAL A 1 407 ? -1.319  -37.173 -22.234 1.000 14.941 0 434  VAL A CA   1 ? 
ATOM   6755 C C    . VAL A 1 407 ? -2.189  -37.165 -20.973 1.000 14.304 0 434  VAL A C    1 ? 
ATOM   6756 O O    . VAL A 1 407 ? -3.149  -37.895 -20.925 1.000 14.507 0 434  VAL A O    1 ? 
ATOM   6757 C CB   . VAL A 1 407 ? -0.435  -38.425 -22.268 1.000 17.683 0 434  VAL A CB   1 ? 
ATOM   6758 C CG1  . VAL A 1 407 ? 0.472   -38.492 -21.070 1.000 19.093 0 434  VAL A CG1  1 ? 
ATOM   6759 C CG2  . VAL A 1 407 ? -1.306  -39.673 -22.370 1.000 21.205 0 434  VAL A CG2  1 ? 
ATOM   6760 H H    . VAL A 1 407 ? 0.334   -35.955 -22.372 1.000 12.465 0 434  VAL A H    1 c 
ATOM   6761 H HA   . VAL A 1 407 ? -1.928  -37.240 -22.994 1.000 14.621 0 434  VAL A HA   1 c 
ATOM   6762 H HB   . VAL A 1 407 ? 0.124   -38.370 -23.078 1.000 17.981 0 434  VAL A HB   1 c 
ATOM   6763 H HG11 . VAL A 1 407 ? -0.056  -38.637 -20.267 1.000 18.610 0 434  VAL A HG11 1 c 
ATOM   6764 H HG12 . VAL A 1 407 ? 0.963   -37.659 -20.988 1.000 18.551 0 434  VAL A HG12 1 c 
ATOM   6765 H HG13 . VAL A 1 407 ? 1.099   -39.227 -21.180 1.000 18.630 0 434  VAL A HG13 1 c 
ATOM   6766 H HG21 . VAL A 1 407 ? -0.755  -40.429 -22.629 1.000 20.171 0 434  VAL A HG21 1 c 
ATOM   6767 H HG22 . VAL A 1 407 ? -2.000  -39.534 -23.035 1.000 20.027 0 434  VAL A HG22 1 c 
ATOM   6768 H HG23 . VAL A 1 407 ? -1.716  -39.857 -21.508 1.000 20.031 0 434  VAL A HG23 1 c 
ATOM   6769 N N    . GLY A 1 408 ? -1.887  -36.288 -20.002 1.000 12.826 0 435  GLY A N    1 ? 
ATOM   6770 C CA   . GLY A 1 408 ? -2.701  -36.185 -18.810 1.000 13.984 0 435  GLY A CA   1 ? 
ATOM   6771 C C    . GLY A 1 408 ? -4.094  -35.637 -19.091 1.000 15.202 0 435  GLY A C    1 ? 
ATOM   6772 O O    . GLY A 1 408 ? -4.975  -35.791 -18.241 1.000 18.557 0 435  GLY A O    1 ? 
ATOM   6773 H H    . GLY A 1 408 ? -1.137  -35.773 -20.072 1.000 13.397 0 435  GLY A H    1 c 
ATOM   6774 H HA2  . GLY A 1 408 ? -2.775  -37.075 -18.392 1.000 13.957 0 435  GLY A HA2  1 c 
ATOM   6775 H HA3  . GLY A 1 408 ? -2.241  -35.594 -18.182 1.000 13.942 0 435  GLY A HA3  1 c 
ATOM   6776 N N    . TRP A 1 409 ? -4.305  -34.971 -20.260 1.000 11.661 0 436  TRP A N    1 ? 
ATOM   6777 C CA   . TRP A 1 409 ? -5.616  -34.569 -20.778 1.000 11.233 0 436  TRP A CA   1 ? 
ATOM   6778 C C    . TRP A 1 409 ? -6.328  -35.731 -21.475 1.000 13.090 0 436  TRP A C    1 ? 
ATOM   6779 O O    . TRP A 1 409 ? -7.545  -35.743 -21.676 1.000 12.316 0 436  TRP A O    1 ? 
ATOM   6780 C CB   . TRP A 1 409 ? -5.461  -33.426 -21.793 1.000 10.540 0 436  TRP A CB   1 ? 
ATOM   6781 C CG   . TRP A 1 409 ? -4.978  -32.090 -21.296 1.000 9.151  0 436  TRP A CG   1 ? 
ATOM   6782 C CD1  . TRP A 1 409 ? -3.741  -31.733 -20.839 1.000 9.204  0 436  TRP A CD1  1 ? 
ATOM   6783 C CD2  . TRP A 1 409 ? -5.772  -30.884 -21.235 1.000 8.629  0 436  TRP A CD2  1 ? 
ATOM   6784 N NE1  . TRP A 1 409 ? -3.690  -30.394 -20.562 1.000 8.791  0 436  TRP A NE1  1 ? 
ATOM   6785 C CE2  . TRP A 1 409 ? -4.928  -29.843 -20.802 1.000 8.574  0 436  TRP A CE2  1 ? 
ATOM   6786 C CE3  . TRP A 1 409 ? -7.115  -30.562 -21.542 1.000 9.033  0 436  TRP A CE3  1 ? 
ATOM   6787 C CZ2  . TRP A 1 409 ? -5.366  -28.533 -20.636 1.000 9.742  0 436  TRP A CZ2  1 ? 
ATOM   6788 C CZ3  . TRP A 1 409 ? -7.515  -29.252 -21.410 1.000 9.484  0 436  TRP A CZ3  1 ? 
ATOM   6789 C CH2  . TRP A 1 409 ? -6.657  -28.268 -20.975 1.000 9.607  0 436  TRP A CH2  1 ? 
ATOM   6790 H H    . TRP A 1 409 ? -3.571  -34.743 -20.755 1.000 12.315 0 436  TRP A H    1 c 
ATOM   6791 H HA   . TRP A 1 409 ? -6.177  -34.251 -20.021 1.000 11.530 0 436  TRP A HA   1 c 
ATOM   6792 H HB2  . TRP A 1 409 ? -4.852  -33.730 -22.499 1.000 10.371 0 436  TRP A HB2  1 c 
ATOM   6793 H HB3  . TRP A 1 409 ? -6.328  -33.293 -22.232 1.000 10.366 0 436  TRP A HB3  1 c 
ATOM   6794 H HD1  . TRP A 1 409 ? -2.996  -32.311 -20.794 1.000 9.111  0 436  TRP A HD1  1 c 
ATOM   6795 H HE1  . TRP A 1 409 ? -2.991  -29.965 -20.262 1.000 8.845  0 436  TRP A HE1  1 c 
ATOM   6796 H HE3  . TRP A 1 409 ? -7.707  -31.221 -21.862 1.000 9.048  0 436  TRP A HE3  1 c 
ATOM   6797 H HZ2  . TRP A 1 409 ? -4.783  -27.853 -20.346 1.000 9.427  0 436  TRP A HZ2  1 c 
ATOM   6798 H HZ3  . TRP A 1 409 ? -8.410  -29.025 -21.606 1.000 9.397  0 436  TRP A HZ3  1 c 
ATOM   6799 H HH2  . TRP A 1 409 ? -6.984  -27.392 -20.869 1.000 9.592  0 436  TRP A HH2  1 c 
ATOM   6800 N N    . ALA A 1 410 ? -5.563  -36.711 -21.985 1.000 15.323 0 437  ALA A N    1 ? 
ATOM   6801 C CA   . ALA A 1 410 ? -6.158  -37.642 -22.938 1.000 14.314 0 437  ALA A CA   1 ? 
ATOM   6802 C C    . ALA A 1 410 ? -7.071  -38.632 -22.249 1.000 13.232 0 437  ALA A C    1 ? 
ATOM   6803 O O    . ALA A 1 410 ? -8.085  -38.995 -22.837 1.000 12.797 0 437  ALA A O    1 ? 
ATOM   6804 C CB   . ALA A 1 410 ? -5.042  -38.343 -23.709 1.000 15.685 0 437  ALA A CB   1 ? 
ATOM   6805 H H    . ALA A 1 410 ? -4.686  -36.802 -21.745 1.000 14.516 0 437  ALA A H    1 c 
ATOM   6806 H HA   . ALA A 1 410 ? -6.706  -37.115 -23.583 1.000 14.501 0 437  ALA A HA   1 c 
ATOM   6807 H HB1  . ALA A 1 410 ? -4.358  -37.697 -23.954 1.000 15.280 0 437  ALA A HB1  1 c 
ATOM   6808 H HB2  . ALA A 1 410 ? -4.644  -39.035 -23.153 1.000 15.292 0 437  ALA A HB2  1 c 
ATOM   6809 H HB3  . ALA A 1 410 ? -5.406  -38.745 -24.515 1.000 15.306 0 437  ALA A HB3  1 c 
ATOM   6810 N N    . THR A 1 411 ? -6.728  -39.071 -21.048 1.000 14.221 0 438  THR A N    1 ? 
ATOM   6811 C CA   . THR A 1 411 ? -7.551  -40.035 -20.340 1.000 15.618 0 438  THR A CA   1 ? 
ATOM   6812 C C    . THR A 1 411 ? -8.935  -39.442 -20.052 1.000 13.328 0 438  THR A C    1 ? 
ATOM   6813 O O    . THR A 1 411 ? -9.966  -40.071 -20.272 1.000 11.684 0 438  THR A O    1 ? 
ATOM   6814 C CB   . THR A 1 411 ? -6.825  -40.513 -19.079 1.000 21.621 0 438  THR A CB   1 ? 
ATOM   6815 O OG1  . THR A 1 411 ? -5.834  -41.375 -19.654 1.000 31.904 0 438  THR A OG1  1 ? 
ATOM   6816 C CG2  . THR A 1 411 ? -7.698  -41.273 -18.108 1.000 25.662 0 438  THR A CG2  1 ? 
ATOM   6817 H H    . THR A 1 411 ? -5.958  -38.772 -20.656 1.000 14.380 0 438  THR A H    1 c 
ATOM   6818 H HA   . THR A 1 411 ? -7.673  -40.812 -20.929 1.000 15.873 0 438  THR A HA   1 c 
ATOM   6819 H HB   . THR A 1 411 ? -6.386  -39.756 -18.622 1.000 22.642 0 438  THR A HB   1 c 
ATOM   6820 H HG1  . THR A 1 411 ? -6.224  -42.011 -20.091 0.000 31.930 0 438  THR A HG1  1 c 
ATOM   6821 H HG21 . THR A 1 411 ? -7.165  -41.555 -17.346 1.000 24.389 0 438  THR A HG21 1 c 
ATOM   6822 H HG22 . THR A 1 411 ? -8.068  -42.055 -18.549 1.000 24.392 0 438  THR A HG22 1 c 
ATOM   6823 H HG23 . THR A 1 411 ? -8.421  -40.702 -17.801 1.000 24.393 0 438  THR A HG23 1 c 
ATOM   6824 N N    . PHE A 1 412 ? -8.987  -38.149 -19.705 1.000 11.161 0 439  PHE A N    1 ? 
ATOM   6825 C CA   . PHE A 1 412 ? -10.259 -37.508 -19.421 1.000 10.047 0 439  PHE A CA   1 ? 
ATOM   6826 C C    . PHE A 1 412 ? -11.064 -37.312 -20.707 1.000 9.273  0 439  PHE A C    1 ? 
ATOM   6827 O O    . PHE A 1 412 ? -12.280 -37.480 -20.695 1.000 9.836  0 439  PHE A O    1 ? 
ATOM   6828 C CB   . PHE A 1 412 ? -10.071 -36.198 -18.659 1.000 9.044  0 439  PHE A CB   1 ? 
ATOM   6829 C CG   . PHE A 1 412 ? -9.506  -36.454 -17.278 1.000 10.835 0 439  PHE A CG   1 ? 
ATOM   6830 C CD1  . PHE A 1 412 ? -10.289 -37.057 -16.305 1.000 12.763 0 439  PHE A CD1  1 ? 
ATOM   6831 C CD2  . PHE A 1 412 ? -8.226  -36.088 -16.956 1.000 11.547 0 439  PHE A CD2  1 ? 
ATOM   6832 C CE1  . PHE A 1 412 ? -9.769  -37.334 -15.043 1.000 14.729 0 439  PHE A CE1  1 ? 
ATOM   6833 C CE2  . PHE A 1 412 ? -7.737  -36.335 -15.674 1.000 13.189 0 439  PHE A CE2  1 ? 
ATOM   6834 C CZ   . PHE A 1 412 ? -8.510  -36.950 -14.745 1.000 15.180 0 439  PHE A CZ   1 ? 
ATOM   6835 H H    . PHE A 1 412 ? -8.217  -37.661 -19.637 1.000 11.397 0 439  PHE A H    1 c 
ATOM   6836 H HA   . PHE A 1 412 ? -10.778 -38.122 -18.835 1.000 9.952  0 439  PHE A HA   1 c 
ATOM   6837 H HB2  . PHE A 1 412 ? -9.457  -35.621 -19.163 1.000 9.679  0 439  PHE A HB2  1 c 
ATOM   6838 H HB3  . PHE A 1 412 ? -10.941 -35.747 -18.578 1.000 9.655  0 439  PHE A HB3  1 c 
ATOM   6839 H HD1  . PHE A 1 412 ? -11.166 -37.332 -16.520 1.000 12.693 0 439  PHE A HD1  1 c 
ATOM   6840 H HD2  . PHE A 1 412 ? -7.681  -35.661 -17.598 1.000 11.742 0 439  PHE A HD2  1 c 
ATOM   6841 H HE1  . PHE A 1 412 ? -10.310 -37.743 -14.386 1.000 14.291 0 439  PHE A HE1  1 c 
ATOM   6842 H HE2  . PHE A 1 412 ? -6.858  -36.086 -15.456 1.000 13.209 0 439  PHE A HE2  1 c 
ATOM   6843 H HZ   . PHE A 1 412 ? -8.164  -37.114 -13.883 1.000 14.509 0 439  PHE A HZ   1 c 
ATOM   6844 N N    . LEU A 1 413 ? -10.418 -36.963 -21.827 1.000 8.893  0 440  LEU A N    1 ? 
ATOM   6845 C CA   . LEU A 1 413 ? -11.118 -36.874 -23.102 1.000 9.252  0 440  LEU A CA   1 ? 
ATOM   6846 C C    . LEU A 1 413 ? -11.796 -38.206 -23.444 1.000 8.910  0 440  LEU A C    1 ? 
ATOM   6847 O O    . LEU A 1 413 ? -12.989 -38.253 -23.745 1.000 9.153  0 440  LEU A O    1 ? 
ATOM   6848 C CB   . LEU A 1 413 ? -10.176 -36.467 -24.238 1.000 10.006 0 440  LEU A CB   1 ? 
ATOM   6849 C CG   . LEU A 1 413 ? -10.790 -36.513 -25.634 1.000 9.835  0 440  LEU A CG   1 ? 
ATOM   6850 C CD1  . LEU A 1 413 ? -11.996 -35.601 -25.787 1.000 10.028 0 440  LEU A CD1  1 ? 
ATOM   6851 C CD2  . LEU A 1 413 ? -9.721  -36.181 -26.659 1.000 11.390 0 440  LEU A CD2  1 ? 
ATOM   6852 H H    . LEU A 1 413 ? -9.525  -36.771 -21.796 1.000 9.087  0 440  LEU A H    1 c 
ATOM   6853 H HA   . LEU A 1 413 ? -11.824 -36.184 -23.011 1.000 9.259  0 440  LEU A HA   1 c 
ATOM   6854 H HB2  . LEU A 1 413 ? -9.862  -35.549 -24.065 1.000 9.793  0 440  LEU A HB2  1 c 
ATOM   6855 H HB3  . LEU A 1 413 ? -9.394  -37.065 -24.220 1.000 9.804  0 440  LEU A HB3  1 c 
ATOM   6856 H HG   . LEU A 1 413 ? -11.090 -37.442 -25.808 1.000 10.171 0 440  LEU A HG   1 c 
ATOM   6857 H HD11 . LEU A 1 413 ? -12.706 -35.896 -25.192 1.000 9.956  0 440  LEU A HD11 1 c 
ATOM   6858 H HD12 . LEU A 1 413 ? -12.312 -35.632 -26.706 1.000 9.962  0 440  LEU A HD12 1 c 
ATOM   6859 H HD13 . LEU A 1 413 ? -11.744 -34.690 -25.563 1.000 9.941  0 440  LEU A HD13 1 c 
ATOM   6860 H HD21 . LEU A 1 413 ? -9.001  -36.830 -26.600 1.000 10.906 0 440  LEU A HD21 1 c 
ATOM   6861 H HD22 . LEU A 1 413 ? -9.370  -35.291 -26.486 1.000 10.906 0 440  LEU A HD22 1 c 
ATOM   6862 H HD23 . LEU A 1 413 ? -10.107 -36.207 -27.551 1.000 10.906 0 440  LEU A HD23 1 c 
ATOM   6863 N N    . VAL A 1 414 ? -11.036 -39.306 -23.356 1.000 9.018  0 441  VAL A N    1 ? 
ATOM   6864 C CA   . VAL A 1 414 ? -11.593 -40.610 -23.685 1.000 9.722  0 441  VAL A CA   1 ? 
ATOM   6865 C C    . VAL A 1 414 ? -12.780 -40.947 -22.768 1.000 9.618  0 441  VAL A C    1 ? 
ATOM   6866 O O    . VAL A 1 414 ? -13.812 -41.409 -23.254 1.000 10.848 0 441  VAL A O    1 ? 
ATOM   6867 C CB   . VAL A 1 414 ? -10.523 -41.690 -23.608 1.000 11.329 0 441  VAL A CB   1 ? 
ATOM   6868 C CG1  . VAL A 1 414 ? -11.151 -43.080 -23.687 1.000 12.665 0 441  VAL A CG1  1 ? 
ATOM   6869 C CG2  . VAL A 1 414 ? -9.500  -41.525 -24.722 1.000 12.584 0 441  VAL A CG2  1 ? 
ATOM   6870 H H    . VAL A 1 414 ? -10.164 -39.244 -23.091 1.000 9.207  0 441  VAL A H    1 c 
ATOM   6871 H HA   . VAL A 1 414 ? -11.921 -40.573 -24.604 1.000 9.835  0 441  VAL A HA   1 c 
ATOM   6872 H HB   . VAL A 1 414 ? -10.065 -41.597 -22.740 1.000 11.441 0 441  VAL A HB   1 c 
ATOM   6873 H HG11 . VAL A 1 414 ? -11.788 -43.108 -24.421 1.000 12.249 0 441  VAL A HG11 1 c 
ATOM   6874 H HG12 . VAL A 1 414 ? -11.607 -43.282 -22.853 1.000 12.247 0 441  VAL A HG12 1 c 
ATOM   6875 H HG13 . VAL A 1 414 ? -10.455 -43.741 -23.840 1.000 12.291 0 441  VAL A HG13 1 c 
ATOM   6876 H HG21 . VAL A 1 414 ? -8.822  -42.218 -24.645 1.000 12.191 0 441  VAL A HG21 1 c 
ATOM   6877 H HG22 . VAL A 1 414 ? -9.079  -40.652 -24.652 1.000 12.160 0 441  VAL A HG22 1 c 
ATOM   6878 H HG23 . VAL A 1 414 ? -9.943  -41.602 -25.584 1.000 12.190 0 441  VAL A HG23 1 c 
ATOM   6879 N N    . GLN A 1 415 ? -12.665 -40.680 -21.475 1.000 10.350 0 442  GLN A N    1 ? 
ATOM   6880 C CA   . GLN A 1 415 ? -13.745 -40.954 -20.532 1.000 10.726 0 442  GLN A CA   1 ? 
ATOM   6881 C C    . GLN A 1 415 ? -14.964 -40.103 -20.878 1.000 9.502  0 442  GLN A C    1 ? 
ATOM   6882 O O    . GLN A 1 415 ? -16.097 -40.593 -20.854 1.000 10.774 0 442  GLN A O    1 ? 
ATOM   6883 C CB   . GLN A 1 415 ? -13.249 -40.655 -19.134 1.000 12.119 0 442  GLN A CB   1 ? 
ATOM   6884 C CG   . GLN A 1 415 ? -14.248 -40.880 -18.008 1.000 16.035 0 442  GLN A CG   1 ? 
ATOM   6885 C CD   . GLN A 1 415 ? -13.637 -40.430 -16.690 1.000 19.743 0 442  GLN A CD   1 ? 
ATOM   6886 O OE1  . GLN A 1 415 ? -13.343 -39.251 -16.438 1.000 17.801 0 442  GLN A OE1  1 ? 
ATOM   6887 N NE2  . GLN A 1 415 ? -13.410 -41.397 -15.804 1.000 28.364 0 442  GLN A NE2  1 ? 
ATOM   6888 H H    . GLN A 1 415 ? -11.887 -40.319 -21.159 1.000 10.268 0 442  GLN A H    1 c 
ATOM   6889 H HA   . GLN A 1 415 ? -13.989 -41.912 -20.600 1.000 10.656 0 442  GLN A HA   1 c 
ATOM   6890 H HB2  . GLN A 1 415 ? -12.461 -41.211 -18.965 1.000 12.567 0 442  GLN A HB2  1 c 
ATOM   6891 H HB3  . GLN A 1 415 ? -12.957 -39.720 -19.108 1.000 12.579 0 442  GLN A HB3  1 c 
ATOM   6892 H HG2  . GLN A 1 415 ? -15.067 -40.370 -18.181 1.000 15.749 0 442  GLN A HG2  1 c 
ATOM   6893 H HG3  . GLN A 1 415 ? -14.483 -41.830 -17.959 1.000 15.963 0 442  GLN A HG3  1 c 
ATOM   6894 H HE21 . GLN A 1 415 ? -13.356 -42.246 -16.069 1.000 25.147 0 442  GLN A HE21 1 c 
ATOM   6895 H HE22 . GLN A 1 415 ? -13.310 -41.189 -14.943 1.000 25.242 0 442  GLN A HE22 1 c 
ATOM   6896 N N    . SER A 1 416 ? -14.767 -38.798 -21.106 1.000 8.658  0 443  SER A N    1 ? 
ATOM   6897 C CA   . SER A 1 416 ? -15.896 -37.928 -21.404 1.000 8.676  0 443  SER A CA   1 ? 
ATOM   6898 C C    . SER A 1 416 ? -16.619 -38.329 -22.694 1.000 9.567  0 443  SER A C    1 ? 
ATOM   6899 O O    . SER A 1 416 ? -17.840 -38.332 -22.767 1.000 10.688 0 443  SER A O    1 ? 
ATOM   6900 C CB   . SER A 1 416 ? -15.482 -36.503 -21.411 1.000 8.421  0 443  SER A CB   1 ? 
ATOM   6901 O OG   . SER A 1 416 ? -15.076 -36.075 -20.096 1.000 9.066  0 443  SER A OG   1 ? 
ATOM   6902 H H    . SER A 1 416 ? -13.925 -38.445 -21.072 1.000 8.874  0 443  SER A H    1 c 
ATOM   6903 H HA   . SER A 1 416 ? -16.546 -38.037 -20.664 1.000 8.792  0 443  SER A HA   1 c 
ATOM   6904 H HB2  . SER A 1 416 ? -14.740 -36.386 -22.035 1.000 8.630  0 443  SER A HB2  1 c 
ATOM   6905 H HB3  . SER A 1 416 ? -16.227 -35.952 -21.717 1.000 8.633  0 443  SER A HB3  1 c 
ATOM   6906 H HG   . SER A 1 416 ? -14.847 -35.261 -20.137 0.000 9.050  0 443  SER A HG   1 c 
ATOM   6907 N N    . LEU A 1 417 ? -15.862 -38.611 -23.756 1.000 9.552  0 444  LEU A N    1 ? 
ATOM   6908 C CA   . LEU A 1 417 ? -16.450 -39.047 -25.015 1.000 10.357 0 444  LEU A CA   1 ? 
ATOM   6909 C C    . LEU A 1 417 ? -17.310 -40.281 -24.781 1.000 11.009 0 444  LEU A C    1 ? 
ATOM   6910 O O    . LEU A 1 417 ? -18.439 -40.360 -25.316 1.000 12.404 0 444  LEU A O    1 ? 
ATOM   6911 C CB   . LEU A 1 417 ? -15.368 -39.377 -26.050 1.000 10.982 0 444  LEU A CB   1 ? 
ATOM   6912 C CG   . LEU A 1 417 ? -14.513 -38.247 -26.589 1.000 11.011 0 444  LEU A CG   1 ? 
ATOM   6913 C CD1  . LEU A 1 417 ? -13.420 -38.901 -27.472 1.000 12.096 0 444  LEU A CD1  1 ? 
ATOM   6914 C CD2  . LEU A 1 417 ? -15.295 -37.241 -27.370 1.000 12.204 0 444  LEU A CD2  1 ? 
ATOM   6915 H H    . LEU A 1 417 ? -14.954 -38.525 -23.698 1.000 9.724  0 444  LEU A H    1 c 
ATOM   6916 H HA   . LEU A 1 417 ? -17.025 -38.319 -25.362 1.000 10.436 0 444  LEU A HA   1 c 
ATOM   6917 H HB2  . LEU A 1 417 ? -14.769 -40.052 -25.653 1.000 10.885 0 444  LEU A HB2  1 c 
ATOM   6918 H HB3  . LEU A 1 417 ? -15.810 -39.811 -26.815 1.000 10.999 0 444  LEU A HB3  1 c 
ATOM   6919 H HG   . LEU A 1 417 ? -14.077 -37.787 -25.828 1.000 11.399 0 444  LEU A HG   1 c 
ATOM   6920 H HD11 . LEU A 1 417 ? -12.869 -39.488 -26.928 1.000 11.765 0 444  LEU A HD11 1 c 
ATOM   6921 H HD12 . LEU A 1 417 ? -12.863 -38.208 -27.865 1.000 11.770 0 444  LEU A HD12 1 c 
ATOM   6922 H HD13 . LEU A 1 417 ? -13.840 -39.417 -28.180 1.000 11.770 0 444  LEU A HD13 1 c 
ATOM   6923 H HD21 . LEU A 1 417 ? -15.946 -36.812 -26.790 1.000 11.815 0 444  LEU A HD21 1 c 
ATOM   6924 H HD22 . LEU A 1 417 ? -15.757 -37.684 -28.101 1.000 11.829 0 444  LEU A HD22 1 c 
ATOM   6925 H HD23 . LEU A 1 417 ? -14.692 -36.569 -27.730 1.000 11.829 0 444  LEU A HD23 1 c 
ATOM   6926 N N    . GLY A 1 418 ? -16.816 -41.192 -23.967 1.000 11.445 0 445  GLY A N    1 ? 
ATOM   6927 C CA   . GLY A 1 418 ? -17.466 -42.477 -23.724 1.000 12.809 0 445  GLY A CA   1 ? 
ATOM   6928 C C    . GLY A 1 418 ? -18.739 -42.345 -22.888 1.000 13.078 0 445  GLY A C    1 ? 
ATOM   6929 O O    . GLY A 1 418 ? -19.543 -43.299 -22.892 1.000 15.250 0 445  GLY A O    1 ? 
ATOM   6930 H H    . GLY A 1 418 ? -16.027 -41.021 -23.541 1.000 11.594 0 445  GLY A H    1 c 
ATOM   6931 H HA2  . GLY A 1 418 ? -17.687 -42.892 -24.591 1.000 12.530 0 445  GLY A HA2  1 c 
ATOM   6932 H HA3  . GLY A 1 418 ? -16.833 -43.071 -23.259 1.000 12.579 0 445  GLY A HA3  1 c 
ATOM   6933 N N    . ARG A 1 419 ? -19.006 -41.197 -22.249 1.000 11.474 0 446  ARG A N    1 ? 
ATOM   6934 C CA   . ARG A 1 419 ? -20.245 -40.985 -21.505 1.000 11.185 0 446  ARG A CA   1 ? 
ATOM   6935 C C    . ARG A 1 419 ? -21.430 -40.828 -22.444 1.000 12.424 0 446  ARG A C    1 ? 
ATOM   6936 O O    . ARG A 1 419 ? -22.579 -40.901 -22.006 1.000 15.097 0 446  ARG A O    1 ? 
ATOM   6937 C CB   . ARG A 1 419 ? -20.095 -39.715 -20.663 1.000 11.039 0 446  ARG A CB   1 ? 
ATOM   6938 C CG   . ARG A 1 419 ? -19.161 -39.834 -19.492 1.000 10.664 0 446  ARG A CG   1 ? 
ATOM   6939 C CD   . ARG A 1 419 ? -19.694 -40.687 -18.378 1.000 12.727 0 446  ARG A CD   1 ? 
ATOM   6940 N NE   . ARG A 1 419 ? -18.829 -40.723 -17.207 1.000 13.109 0 446  ARG A NE   1 ? 
ATOM   6941 C CZ   . ARG A 1 419 ? -18.880 -41.606 -16.242 1.000 15.685 0 446  ARG A CZ   1 ? 
ATOM   6942 N NH1  . ARG A 1 419 ? -19.668 -42.651 -16.360 1.000 17.981 0 446  ARG A NH1  1 ? 
ATOM   6943 N NH2  . ARG A 1 419 ? -18.109 -41.425 -15.181 1.000 17.422 0 446  ARG A NH2  1 ? 
ATOM   6944 H H    . ARG A 1 419 ? -18.386 -40.526 -22.264 1.000 11.739 0 446  ARG A H    1 c 
ATOM   6945 H HA   . ARG A 1 419 ? -20.399 -41.765 -20.915 1.000 11.469 0 446  ARG A HA   1 c 
ATOM   6946 H HB2  . ARG A 1 419 ? -19.780 -38.990 -21.242 1.000 10.989 0 446  ARG A HB2  1 c 
ATOM   6947 H HB3  . ARG A 1 419 ? -20.981 -39.459 -20.327 1.000 10.992 0 446  ARG A HB3  1 c 
ATOM   6948 H HG2  . ARG A 1 419 ? -18.311 -40.214 -19.800 1.000 11.195 0 446  ARG A HG2  1 c 
ATOM   6949 H HG3  . ARG A 1 419 ? -18.973 -38.936 -19.141 1.000 11.189 0 446  ARG A HG3  1 c 
ATOM   6950 H HD2  . ARG A 1 419 ? -20.574 -40.350 -18.115 1.000 12.326 0 446  ARG A HD2  1 c 
ATOM   6951 H HD3  . ARG A 1 419 ? -19.812 -41.597 -18.716 1.000 12.400 0 446  ARG A HD3  1 c 
ATOM   6952 H HE   . ARG A 1 419 ? -18.221 -40.102 -17.144 1.000 13.612 0 446  ARG A HE   1 c 
ATOM   6953 H HH11 . ARG A 1 419 ? -19.393 -43.438 -16.047 1.000 17.209 0 446  ARG A HH11 1 c 
ATOM   6954 H HH12 . ARG A 1 419 ? -20.468 -42.569 -16.742 1.000 17.117 0 446  ARG A HH12 1 c 
ATOM   6955 H HH21 . ARG A 1 419 ? -18.104 -42.032 -14.538 1.000 16.863 0 446  ARG A HH21 1 c 
ATOM   6956 H HH22 . ARG A 1 419 ? -17.602 -40.703 -15.115 1.000 16.804 0 446  ARG A HH22 1 c 
ATOM   6957 N N    . PHE A 1 420 ? -21.174 -40.554 -23.721 1.000 10.959 0 447  PHE A N    1 ? 
ATOM   6958 C CA   . PHE A 1 420 ? -22.192 -40.483 -24.747 1.000 11.286 0 447  PHE A CA   1 ? 
ATOM   6959 C C    . PHE A 1 420 ? -22.196 -41.791 -25.513 1.000 12.484 0 447  PHE A C    1 ? 
ATOM   6960 O O    . PHE A 1 420 ? -21.159 -42.247 -25.987 1.000 12.632 0 447  PHE A O    1 ? 
ATOM   6961 C CB   . PHE A 1 420 ? -21.873 -39.346 -25.713 1.000 11.289 0 447  PHE A CB   1 ? 
ATOM   6962 C CG   . PHE A 1 420 ? -21.905 -37.968 -25.094 1.000 9.698  0 447  PHE A CG   1 ? 
ATOM   6963 C CD1  . PHE A 1 420 ? -20.809 -37.508 -24.380 1.000 10.877 0 447  PHE A CD1  1 ? 
ATOM   6964 C CD2  . PHE A 1 420 ? -23.037 -37.179 -25.151 1.000 10.599 0 447  PHE A CD2  1 ? 
ATOM   6965 C CE1  . PHE A 1 420 ? -20.833 -36.261 -23.799 1.000 10.659 0 447  PHE A CE1  1 ? 
ATOM   6966 C CE2  . PHE A 1 420 ? -23.053 -35.927 -24.584 1.000 11.364 0 447  PHE A CE2  1 ? 
ATOM   6967 C CZ   . PHE A 1 420 ? -21.943 -35.474 -23.900 1.000 11.494 0 447  PHE A CZ   1 ? 
ATOM   6968 H H    . PHE A 1 420 ? -20.311 -40.383 -23.966 1.000 11.365 0 447  PHE A H    1 c 
ATOM   6969 H HA   . PHE A 1 420 ? -23.082 -40.330 -24.332 1.000 11.466 0 447  PHE A HA   1 c 
ATOM   6970 H HB2  . PHE A 1 420 ? -20.979 -39.502 -26.092 1.000 10.905 0 447  PHE A HB2  1 c 
ATOM   6971 H HB3  . PHE A 1 420 ? -22.520 -39.375 -26.453 1.000 10.909 0 447  PHE A HB3  1 c 
ATOM   6972 H HD1  . PHE A 1 420 ? -20.033 -38.042 -24.318 1.000 10.565 0 447  PHE A HD1  1 c 
ATOM   6973 H HD2  . PHE A 1 420 ? -23.790 -37.483 -25.632 1.000 10.569 0 447  PHE A HD2  1 c 
ATOM   6974 H HE1  . PHE A 1 420 ? -20.075 -35.946 -23.333 1.000 10.887 0 447  PHE A HE1  1 c 
ATOM   6975 H HE2  . PHE A 1 420 ? -23.825 -35.388 -24.646 1.000 11.194 0 447  PHE A HE2  1 c 
ATOM   6976 H HZ   . PHE A 1 420 ? -21.955 -34.623 -23.493 1.000 11.245 0 447  PHE A HZ   1 c 
ATOM   6977 N N    . GLU A 1 421 ? -23.351 -42.434 -25.622 1.000 12.060 0 448  GLU A N    1 ? 
ATOM   6978 C CA   . GLU A 1 421 ? -23.409 -43.674 -26.352 1.000 13.288 0 448  GLU A CA   1 ? 
ATOM   6979 C C    . GLU A 1 421 ? -23.131 -43.441 -27.831 1.000 12.030 0 448  GLU A C    1 ? 
ATOM   6980 O O    . GLU A 1 421 ? -23.379 -42.378 -28.369 1.000 10.786 0 448  GLU A O    1 ? 
ATOM   6981 C CB   . GLU A 1 421 ? -24.813 -44.270 -26.262 1.000 18.573 0 448  GLU A CB   1 ? 
ATOM   6982 C CG   . GLU A 1 421 ? -24.998 -45.172 -25.054 1.000 27.093 0 448  GLU A CG   1 ? 
ATOM   6983 C CD   . GLU A 1 421 ? -24.019 -46.335 -25.074 1.000 36.992 0 448  GLU A CD   1 ? 
ATOM   6984 O OE1  . GLU A 1 421 ? -23.112 -46.427 -24.179 1.000 44.735 0 448  GLU A OE1  1 ? 
ATOM   6985 O OE2  . GLU A 1 421 ? -24.132 -47.122 -26.054 1.000 51.680 0 448  GLU A OE2  1 ? 
ATOM   6986 H H    . GLU A 1 421 ? -24.109 -42.099 -25.236 1.000 12.492 0 448  GLU A H    1 c 
ATOM   6987 H HA   . GLU A 1 421 ? -22.736 -44.299 -25.983 1.000 13.723 0 448  GLU A HA   1 c 
ATOM   6988 H HB2  . GLU A 1 421 ? -25.468 -43.542 -26.226 1.000 18.666 0 448  GLU A HB2  1 c 
ATOM   6989 H HB3  . GLU A 1 421 ? -24.991 -44.791 -27.074 1.000 18.778 0 448  GLU A HB3  1 c 
ATOM   6990 H HG2  . GLU A 1 421 ? -24.860 -44.652 -24.233 1.000 26.685 0 448  GLU A HG2  1 c 
ATOM   6991 H HG3  . GLU A 1 421 ? -25.913 -45.525 -25.046 1.000 26.685 0 448  GLU A HG3  1 c 
ATOM   6992 N N    . GLY A 1 422 ? -22.690 -44.482 -28.525 1.000 12.731 0 449  GLY A N    1 ? 
ATOM   6993 C CA   . GLY A 1 422 ? -22.309 -44.375 -29.915 1.000 13.123 0 449  GLY A CA   1 ? 
ATOM   6994 C C    . GLY A 1 422 ? -23.460 -43.876 -30.780 1.000 12.857 0 449  GLY A C    1 ? 
ATOM   6995 O O    . GLY A 1 422 ? -23.258 -43.058 -31.695 1.000 13.582 0 449  GLY A O    1 ? 
ATOM   6996 H H    . GLY A 1 422 ? -22.624 -45.296 -28.115 1.000 12.660 0 449  GLY A H    1 c 
ATOM   6997 H HA2  . GLY A 1 422 ? -21.548 -43.755 -29.993 1.000 12.985 0 449  GLY A HA2  1 c 
ATOM   6998 H HA3  . GLY A 1 422 ? -22.015 -45.258 -30.234 1.000 13.035 0 449  GLY A HA3  1 c 
ATOM   6999 N N    . GLN A 1 423 ? -24.687 -44.301 -30.476 1.000 12.287 0 450  GLN A N    1 ? 
ATOM   7000 C CA   . GLN A 1 423 ? -25.828 -43.865 -31.259 1.000 12.982 0 450  GLN A CA   1 ? 
ATOM   7001 C C    . GLN A 1 423 ? -26.098 -42.364 -31.126 1.000 13.071 0 450  GLN A C    1 ? 
ATOM   7002 O O    . GLN A 1 423 ? -26.685 -41.758 -32.013 1.000 17.992 0 450  GLN A O    1 ? 
ATOM   7003 C CB   . GLN A 1 423 ? -27.083 -44.647 -30.914 1.000 16.481 0 450  GLN A CB   1 ? 
ATOM   7004 C CG   . GLN A 1 423 ? -26.975 -46.099 -31.334 1.000 20.563 0 450  GLN A CG   1 ? 
ATOM   7005 C CD   . GLN A 1 423 ? -28.083 -46.939 -30.750 1.000 27.187 0 450  GLN A CD   1 ? 
ATOM   7006 O OE1  . GLN A 1 423 ? -29.102 -46.415 -30.275 1.000 34.255 0 450  GLN A OE1  1 ? 
ATOM   7007 N NE2  . GLN A 1 423 ? -27.864 -48.248 -30.811 1.000 29.521 0 450  GLN A NE2  1 ? 
ATOM   7008 H H    . GLN A 1 423 ? -24.817 -44.875 -29.776 1.000 12.599 0 450  GLN A H    1 c 
ATOM   7009 H HA   . GLN A 1 423 ? -25.625 -44.050 -32.211 1.000 13.446 0 450  GLN A HA   1 c 
ATOM   7010 H HB2  . GLN A 1 423 ? -27.234 -44.599 -29.947 1.000 16.527 0 450  GLN A HB2  1 c 
ATOM   7011 H HB3  . GLN A 1 423 ? -27.851 -44.238 -31.363 1.000 16.418 0 450  GLN A HB3  1 c 
ATOM   7012 H HG2  . GLN A 1 423 ? -27.007 -46.159 -32.312 1.000 20.850 0 450  GLN A HG2  1 c 
ATOM   7013 H HG3  . GLN A 1 423 ? -26.112 -46.458 -31.038 1.000 20.837 0 450  GLN A HG3  1 c 
ATOM   7014 H HE21 . GLN A 1 423 ? -27.162 -48.564 -31.252 1.000 28.634 0 450  GLN A HE21 1 c 
ATOM   7015 H HE22 . GLN A 1 423 ? -28.423 -48.807 -30.408 1.000 28.747 0 450  GLN A HE22 1 c 
ATOM   7016 N N    . VAL A 1 424 ? -25.707 -41.744 -30.013 1.000 9.974  0 451  VAL A N    1 ? 
ATOM   7017 C CA   . VAL A 1 424 ? -25.808 -40.301 -29.871 1.000 9.928  0 451  VAL A CA   1 ? 
ATOM   7018 C C    . VAL A 1 424 ? -24.678 -39.640 -30.667 1.000 9.278  0 451  VAL A C    1 ? 
ATOM   7019 O O    . VAL A 1 424 ? -24.925 -38.662 -31.369 1.000 10.247 0 451  VAL A O    1 ? 
ATOM   7020 C CB   . VAL A 1 424 ? -25.771 -39.942 -28.379 1.000 10.991 0 451  VAL A CB   1 ? 
ATOM   7021 C CG1  . VAL A 1 424 ? -25.820 -38.436 -28.194 1.000 10.488 0 451  VAL A CG1  1 ? 
ATOM   7022 C CG2  . VAL A 1 424 ? -26.879 -40.635 -27.604 1.000 12.574 0 451  VAL A CG2  1 ? 
ATOM   7023 H H    . VAL A 1 424 ? -25.361 -42.233 -29.322 1.000 10.694 0 451  VAL A H    1 c 
ATOM   7024 H HA   . VAL A 1 424 ? -26.665 -40.009 -30.240 1.000 10.049 0 451  VAL A HA   1 c 
ATOM   7025 H HB   . VAL A 1 424 ? -24.908 -40.261 -28.024 1.000 10.962 0 451  VAL A HB   1 c 
ATOM   7026 H HG11 . VAL A 1 424 ? -26.548 -38.067 -28.723 1.000 10.632 0 451  VAL A HG11 1 c 
ATOM   7027 H HG12 . VAL A 1 424 ? -24.979 -38.043 -28.482 1.000 10.626 0 451  VAL A HG12 1 c 
ATOM   7028 H HG13 . VAL A 1 424 ? -25.967 -38.230 -27.255 1.000 10.632 0 451  VAL A HG13 1 c 
ATOM   7029 H HG21 . VAL A 1 424 ? -26.784 -40.437 -26.658 1.000 12.076 0 451  VAL A HG21 1 c 
ATOM   7030 H HG22 . VAL A 1 424 ? -26.822 -41.596 -27.737 1.000 12.058 0 451  VAL A HG22 1 c 
ATOM   7031 H HG23 . VAL A 1 424 ? -27.743 -40.316 -27.916 1.000 12.077 0 451  VAL A HG23 1 c 
ATOM   7032 N N    . ARG A 1 425 ? -23.469 -40.131 -30.455 1.000 9.291  0 452  ARG A N    1 ? 
ATOM   7033 C CA   . ARG A 1 425 ? -22.287 -39.565 -31.114 1.000 9.217  0 452  ARG A CA   1 ? 
ATOM   7034 C C    . ARG A 1 425 ? -22.412 -39.580 -32.640 1.000 11.197 0 452  ARG A C    1 ? 
ATOM   7035 O O    . ARG A 1 425 ? -22.007 -38.618 -33.313 1.000 11.357 0 452  ARG A O    1 ? 
ATOM   7036 C CB   . ARG A 1 425 ? -21.014 -40.269 -30.665 1.000 9.342  0 452  ARG A CB   1 ? 
ATOM   7037 C CG   . ARG A 1 425 ? -20.753 -40.052 -29.195 1.000 9.286  0 452  ARG A CG   1 ? 
ATOM   7038 C CD   . ARG A 1 425 ? -19.452 -40.570 -28.630 1.000 10.411 0 452  ARG A CD   1 ? 
ATOM   7039 N NE   . ARG A 1 425 ? -19.499 -42.001 -28.303 1.000 11.921 0 452  ARG A NE   1 ? 
ATOM   7040 C CZ   . ARG A 1 425 ? -19.025 -43.013 -28.993 1.000 13.631 0 452  ARG A CZ   1 ? 
ATOM   7041 N NH1  . ARG A 1 425 ? -18.474 -42.854 -30.171 1.000 14.557 0 452  ARG A NH1  1 ? 
ATOM   7042 N NH2  . ARG A 1 425 ? -19.070 -44.241 -28.469 1.000 16.180 0 452  ARG A NH2  1 ? 
ATOM   7043 H H    . ARG A 1 425 ? -23.362 -40.839 -29.888 1.000 9.283  0 452  ARG A H    1 c 
ATOM   7044 H HA   . ARG A 1 425 ? -22.213 -38.619 -30.830 1.000 9.591  0 452  ARG A HA   1 c 
ATOM   7045 H HB2  . ARG A 1 425 ? -21.095 -41.231 -30.840 1.000 9.309  0 452  ARG A HB2  1 c 
ATOM   7046 H HB3  . ARG A 1 425 ? -20.254 -39.927 -31.182 1.000 9.342  0 452  ARG A HB3  1 c 
ATOM   7047 H HG2  . ARG A 1 425 ? -20.802 -39.088 -29.014 1.000 9.549  0 452  ARG A HG2  1 c 
ATOM   7048 H HG3  . ARG A 1 425 ? -21.487 -40.462 -28.688 1.000 9.550  0 452  ARG A HG3  1 c 
ATOM   7049 H HD2  . ARG A 1 425 ? -18.737 -40.410 -29.279 1.000 10.556 0 452  ARG A HD2  1 c 
ATOM   7050 H HD3  . ARG A 1 425 ? -19.237 -40.064 -27.820 1.000 10.497 0 452  ARG A HD3  1 c 
ATOM   7051 H HE   . ARG A 1 425 ? -19.894 -42.209 -27.555 1.000 11.974 0 452  ARG A HE   1 c 
ATOM   7052 H HH11 . ARG A 1 425 ? -17.772 -43.342 -30.396 1.000 14.278 0 452  ARG A HH11 1 c 
ATOM   7053 H HH12 . ARG A 1 425 ? -18.808 -42.263 -30.736 1.000 14.268 0 452  ARG A HH12 1 c 
ATOM   7054 H HH21 . ARG A 1 425 ? -18.970 -44.946 -28.997 1.000 15.327 0 452  ARG A HH21 1 c 
ATOM   7055 H HH22 . ARG A 1 425 ? -19.199 -44.348 -27.599 1.000 15.283 0 452  ARG A HH22 1 c 
ATOM   7056 N N    . GLN A 1 426 ? -22.977 -40.643 -33.197 1.000 10.941 0 453  GLN A N    1 ? 
ATOM   7057 C CA   . GLN A 1 426 ? -23.190 -40.800 -34.630 1.000 11.954 0 453  GLN A CA   1 ? 
ATOM   7058 C C    . GLN A 1 426 ? -24.048 -39.693 -35.217 1.000 12.118 0 453  GLN A C    1 ? 
ATOM   7059 O O    . GLN A 1 426 ? -23.954 -39.443 -36.428 1.000 14.844 0 453  GLN A O    1 ? 
ATOM   7060 C CB   . GLN A 1 426 ? -23.897 -42.128 -34.902 1.000 13.909 0 453  GLN A CB   1 ? 
ATOM   7061 C CG   . GLN A 1 426 ? -23.015 -43.367 -34.895 1.000 18.823 0 453  GLN A CG   1 ? 
ATOM   7062 C CD   . GLN A 1 426 ? -23.842 -44.624 -35.129 1.000 23.520 0 453  GLN A CD   1 ? 
ATOM   7063 O OE1  . GLN A 1 426 ? -24.559 -44.707 -36.133 1.000 24.952 0 453  GLN A OE1  1 ? 
ATOM   7064 N NE2  . GLN A 1 426 ? -23.846 -45.588 -34.208 1.000 26.826 0 453  GLN A NE2  1 ? 
ATOM   7065 H H    . GLN A 1 426 ? -23.242 -41.325 -32.649 1.000 11.235 0 453  GLN A H    1 c 
ATOM   7066 H HA   . GLN A 1 426 ? -22.308 -40.798 -35.082 1.000 12.107 0 453  GLN A HA   1 c 
ATOM   7067 H HB2  . GLN A 1 426 ? -24.601 -42.244 -34.229 1.000 14.387 0 453  GLN A HB2  1 c 
ATOM   7068 H HB3  . GLN A 1 426 ? -24.338 -42.067 -35.775 1.000 14.430 0 453  GLN A HB3  1 c 
ATOM   7069 H HG2  . GLN A 1 426 ? -22.338 -43.290 -35.602 1.000 18.514 0 453  GLN A HG2  1 c 
ATOM   7070 H HG3  . GLN A 1 426 ? -22.548 -43.436 -34.036 1.000 18.494 0 453  GLN A HG3  1 c 
ATOM   7071 H HE21 . GLN A 1 426 ? -23.377 -45.493 -33.461 1.000 25.631 0 453  GLN A HE21 1 c 
ATOM   7072 H HE22 . GLN A 1 426 ? -24.320 -46.326 -34.343 1.000 25.725 0 453  GLN A HE22 1 c 
ATOM   7073 N N    . LYS A 1 427 ? -24.911 -39.032 -34.425 1.000 10.836 0 454  LYS A N    1 ? 
ATOM   7074 C CA   . LYS A 1 427 ? -25.839 -38.053 -34.971 1.000 11.843 0 454  LYS A CA   1 ? 
ATOM   7075 C C    . LYS A 1 427 ? -25.175 -36.713 -35.262 1.000 14.463 0 454  LYS A C    1 ? 
ATOM   7076 O O    . LYS A 1 427 ? -25.746 -35.902 -36.001 1.000 17.340 0 454  LYS A O    1 ? 
ATOM   7077 C CB   . LYS A 1 427 ? -27.027 -37.891 -34.042 1.000 11.947 0 454  LYS A CB   1 ? 
ATOM   7078 C CG   . LYS A 1 427 ? -27.859 -39.143 -33.940 1.000 12.878 0 454  LYS A CG   1 ? 
ATOM   7079 C CD   . LYS A 1 427 ? -29.137 -38.868 -33.164 1.000 16.550 0 454  LYS A CD   1 ? 
ATOM   7080 C CE   . LYS A 1 427 ? -30.092 -40.039 -33.160 1.000 18.584 0 454  LYS A CE   1 ? 
ATOM   7081 N NZ   . LYS A 1 427 ? -29.595 -40.975 -32.161 1.000 23.430 0 454  LYS A NZ   1 ? 
ATOM   7082 H H    . LYS A 1 427 ? -24.930 -39.205 -33.528 1.000 11.348 0 454  LYS A H    1 c 
ATOM   7083 H HA   . LYS A 1 427 ? -26.186 -38.410 -35.827 1.000 12.119 0 454  LYS A HA   1 c 
ATOM   7084 H HB2  . LYS A 1 427 ? -26.707 -37.651 -33.147 1.000 12.129 0 454  LYS A HB2  1 c 
ATOM   7085 H HB3  . LYS A 1 427 ? -27.594 -37.160 -34.368 1.000 12.183 0 454  LYS A HB3  1 c 
ATOM   7086 H HG2  . LYS A 1 427 ? -28.082 -39.457 -34.843 1.000 13.402 0 454  LYS A HG2  1 c 
ATOM   7087 H HG3  . LYS A 1 427 ? -27.339 -39.838 -33.485 1.000 13.454 0 454  LYS A HG3  1 c 
ATOM   7088 H HD2  . LYS A 1 427 ? -28.904 -38.639 -32.238 1.000 16.114 0 454  LYS A HD2  1 c 
ATOM   7089 H HD3  . LYS A 1 427 ? -29.588 -38.091 -33.560 1.000 16.032 0 454  LYS A HD3  1 c 
ATOM   7090 H HE2  . LYS A 1 427 ? -30.990 -39.749 -32.922 1.000 19.137 0 454  LYS A HE2  1 c 
ATOM   7091 H HE3  . LYS A 1 427 ? -30.113 -40.469 -34.033 1.000 19.137 0 454  LYS A HE3  1 c 
ATOM   7092 H HZ1  . LYS A 1 427 ? -29.638 -40.600 -31.337 1.000 21.690 0 454  LYS A HZ1  1 c 
ATOM   7093 H HZ2  . LYS A 1 427 ? -28.738 -41.206 -32.338 1.000 21.620 0 454  LYS A HZ2  1 c 
ATOM   7094 H HZ3  . LYS A 1 427 ? -30.107 -41.722 -32.169 1.000 21.754 0 454  LYS A HZ3  1 c 
ATOM   7095 N N    . VAL A 1 428 ? -23.959 -36.474 -34.761 1.000 12.638 0 455  VAL A N    1 ? 
ATOM   7096 C CA   . VAL A 1 428 ? -23.302 -35.213 -35.122 1.000 14.017 0 455  VAL A CA   1 ? 
ATOM   7097 C C    . VAL A 1 428 ? -22.611 -35.365 -36.486 1.000 15.735 0 455  VAL A C    1 ? 
ATOM   7098 O O    . VAL A 1 428 ? -21.764 -36.239 -36.658 1.000 20.071 0 455  VAL A O    1 ? 
ATOM   7099 C CB   . VAL A 1 428 ? -22.314 -34.823 -33.997 1.000 14.057 0 455  VAL A CB   1 ? 
ATOM   7100 C CG1  . VAL A 1 428 ? -21.591 -33.524 -34.317 1.000 16.547 0 455  VAL A CG1  1 ? 
ATOM   7101 C CG2  . VAL A 1 428 ? -23.005 -34.661 -32.681 1.000 13.802 0 455  VAL A CG2  1 ? 
ATOM   7102 H H    . VAL A 1 428 ? -23.543 -37.066 -34.203 1.000 13.339 0 455  VAL A H    1 c 
ATOM   7103 H HA   . VAL A 1 428 ? -23.982 -34.515 -35.189 1.000 14.096 0 455  VAL A HA   1 c 
ATOM   7104 H HB   . VAL A 1 428 ? -21.648 -35.546 -33.920 1.000 14.431 0 455  VAL A HB   1 c 
ATOM   7105 H HG11 . VAL A 1 428 ? -22.243 -32.828 -34.506 1.000 15.762 0 455  VAL A HG11 1 c 
ATOM   7106 H HG12 . VAL A 1 428 ? -21.019 -33.651 -35.092 1.000 15.762 0 455  VAL A HG12 1 c 
ATOM   7107 H HG13 . VAL A 1 428 ? -21.047 -33.258 -33.556 1.000 15.741 0 455  VAL A HG13 1 c 
ATOM   7108 H HG21 . VAL A 1 428 ? -22.375 -34.328 -32.020 1.000 13.854 0 455  VAL A HG21 1 c 
ATOM   7109 H HG22 . VAL A 1 428 ? -23.354 -35.519 -32.388 1.000 13.862 0 455  VAL A HG22 1 c 
ATOM   7110 H HG23 . VAL A 1 428 ? -23.738 -34.029 -32.774 1.000 13.870 0 455  VAL A HG23 1 c 
ATOM   7111 N N    . ARG A 1 429 ? -22.880 -34.441 -37.411 1.000 17.065 0 456  ARG A N    1 ? 
ATOM   7112 C CA   . ARG A 1 429 ? -22.225 -34.396 -38.702 1.000 19.586 0 456  ARG A CA   1 ? 
ATOM   7113 C C    . ARG A 1 429 ? -21.098 -33.369 -38.609 1.000 15.287 0 456  ARG A C    1 ? 
ATOM   7114 O O    . ARG A 1 429 ? -21.372 -32.189 -38.393 1.000 17.409 0 456  ARG A O    1 ? 
ATOM   7115 C CB   . ARG A 1 429 ? -23.223 -33.928 -39.768 1.000 23.636 0 456  ARG A CB   1 ? 
ATOM   7116 C CG   . ARG A 1 429 ? -22.644 -33.673 -41.154 1.000 30.759 0 456  ARG A CG   1 ? 
ATOM   7117 C CD   . ARG A 1 429 ? -22.496 -34.919 -41.943 1.000 34.046 0 456  ARG A CD   1 ? 
ATOM   7118 N NE   . ARG A 1 429 ? -22.397 -34.585 -43.367 1.000 38.937 0 456  ARG A NE   1 ? 
ATOM   7119 C CZ   . ARG A 1 429 ? -21.979 -35.476 -44.252 1.000 38.016 0 456  ARG A CZ   1 ? 
ATOM   7120 N NH1  . ARG A 1 429 ? -21.635 -35.069 -45.459 1.000 41.931 0 456  ARG A NH1  1 ? 
ATOM   7121 N NH2  . ARG A 1 429 ? -21.826 -36.742 -43.904 1.000 36.968 0 456  ARG A NH2  1 ? 
ATOM   7122 H H    . ARG A 1 429 ? -23.507 -33.803 -37.223 1.000 17.298 0 456  ARG A H    1 c 
ATOM   7123 H HA   . ARG A 1 429 ? -21.863 -35.291 -38.924 1.000 18.826 0 456  ARG A HA   1 c 
ATOM   7124 H HB2  . ARG A 1 429 ? -23.930 -34.604 -39.845 1.000 24.155 0 456  ARG A HB2  1 c 
ATOM   7125 H HB3  . ARG A 1 429 ? -23.644 -33.101 -39.452 1.000 24.016 0 456  ARG A HB3  1 c 
ATOM   7126 H HG2  . ARG A 1 429 ? -23.232 -33.054 -41.638 1.000 29.765 0 456  ARG A HG2  1 c 
ATOM   7127 H HG3  . ARG A 1 429 ? -21.765 -33.248 -41.066 1.000 29.657 0 456  ARG A HG3  1 c 
ATOM   7128 H HD2  . ARG A 1 429 ? -21.688 -35.395 -41.661 1.000 34.324 0 456  ARG A HD2  1 c 
ATOM   7129 H HD3  . ARG A 1 429 ? -23.267 -35.505 -41.799 1.000 34.175 0 456  ARG A HD3  1 c 
ATOM   7130 H HE   . ARG A 1 429 ? -22.618 -33.787 -43.639 1.000 37.474 0 456  ARG A HE   1 c 
ATOM   7131 H HH11 . ARG A 1 429 ? -21.623 -35.647 -46.129 1.000 40.647 0 456  ARG A HH11 1 c 
ATOM   7132 H HH12 . ARG A 1 429 ? -21.416 -34.222 -45.595 1.000 40.637 0 456  ARG A HH12 1 c 
ATOM   7133 H HH21 . ARG A 1 429 ? -21.075 -37.165 -44.114 1.000 37.282 0 456  ARG A HH21 1 c 
ATOM   7134 H HH22 . ARG A 1 429 ? -22.475 -37.164 -43.469 1.000 37.265 0 456  ARG A HH22 1 c 
ATOM   7135 N N    . ILE A 1 430 ? -19.913 -33.878 -38.859 1.000 17.553 0 457  ILE A N    1 ? 
ATOM   7136 C CA   . ILE A 1 430 ? -18.723 -33.061 -38.854 1.000 20.843 0 457  ILE A CA   1 ? 
ATOM   7137 C C    . ILE A 1 430 ? -18.427 -32.708 -40.303 1.000 21.550 0 457  ILE A C    1 ? 
ATOM   7138 O O    . ILE A 1 430 ? -18.098 -33.589 -41.116 1.000 24.608 0 457  ILE A O    1 ? 
ATOM   7139 C CB   . ILE A 1 430 ? -17.601 -33.801 -38.114 1.000 22.302 0 457  ILE A CB   1 ? 
ATOM   7140 C CG1  . ILE A 1 430 ? -18.069 -34.052 -36.644 1.000 24.436 0 457  ILE A CG1  1 ? 
ATOM   7141 C CG2  . ILE A 1 430 ? -16.313 -32.989 -38.199 1.000 22.427 0 457  ILE A CG2  1 ? 
ATOM   7142 C CD1  . ILE A 1 430 ? -17.226 -34.987 -35.813 1.000 25.914 0 457  ILE A CD1  1 ? 
ATOM   7143 H H    . ILE A 1 430 ? -19.831 -34.770 -39.041 1.000 17.687 0 457  ILE A H    1 c 
ATOM   7144 H HA   . ILE A 1 430 ? -18.916 -32.241 -38.364 1.000 20.490 0 457  ILE A HA   1 c 
ATOM   7145 H HB   . ILE A 1 430 ? -17.459 -34.666 -38.548 1.000 22.415 0 457  ILE A HB   1 c 
ATOM   7146 H HG12 . ILE A 1 430 ? -18.106 -33.187 -36.185 1.000 24.261 0 457  ILE A HG12 1 c 
ATOM   7147 H HG13 . ILE A 1 430 ? -18.981 -34.406 -36.667 1.000 24.206 0 457  ILE A HG13 1 c 
ATOM   7148 H HG21 . ILE A 1 430 ? -15.645 -33.375 -37.608 1.000 22.424 0 457  ILE A HG21 1 c 
ATOM   7149 H HG22 . ILE A 1 430 ? -16.488 -32.071 -37.930 1.000 22.397 0 457  ILE A HG22 1 c 
ATOM   7150 H HG23 . ILE A 1 430 ? -15.978 -32.999 -39.111 1.000 22.394 0 457  ILE A HG23 1 c 
ATOM   7151 H HD11 . ILE A 1 430 ? -17.188 -35.862 -36.244 1.000 25.461 0 457  ILE A HD11 1 c 
ATOM   7152 H HD12 . ILE A 1 430 ? -17.621 -35.081 -34.926 1.000 25.461 0 457  ILE A HD12 1 c 
ATOM   7153 H HD13 . ILE A 1 430 ? -16.323 -34.628 -35.729 1.000 25.444 0 457  ILE A HD13 1 c 
ATOM   7154 N N    . VAL A 1 431 ? -18.607 -31.419 -40.592 1.000 23.068 0 458  VAL A N    1 ? 
ATOM   7155 C CA   . VAL A 1 431 ? -18.508 -30.910 -41.951 1.000 28.539 0 458  VAL A CA   1 ? 
ATOM   7156 C C    . VAL A 1 431 ? -17.247 -30.073 -42.071 1.000 29.363 0 458  VAL A C    1 ? 
ATOM   7157 O O    . VAL A 1 431 ? -16.852 -29.356 -41.150 1.000 24.528 0 458  VAL A O    1 ? 
ATOM   7158 C CB   . VAL A 1 431 ? -19.726 -30.066 -42.337 1.000 31.206 0 458  VAL A CB   1 ? 
ATOM   7159 C CG1  . VAL A 1 431 ? -21.023 -30.819 -42.080 1.000 35.355 0 458  VAL A CG1  1 ? 
ATOM   7160 C CG2  . VAL A 1 431 ? -19.736 -28.735 -41.625 1.000 33.900 0 458  VAL A CG2  1 ? 
ATOM   7161 H H    . VAL A 1 431 ? -18.794 -30.832 -39.918 1.000 23.872 0 458  VAL A H    1 c 
ATOM   7162 H HA   . VAL A 1 431 ? -18.445 -31.666 -42.565 1.000 27.952 0 458  VAL A HA   1 c 
ATOM   7163 H HB   . VAL A 1 431 ? -19.664 -29.892 -43.306 1.000 31.904 0 458  VAL A HB   1 c 
ATOM   7164 H HG11 . VAL A 1 431 ? -21.127 -30.972 -41.125 1.000 33.957 0 458  VAL A HG11 1 c 
ATOM   7165 H HG12 . VAL A 1 431 ? -21.000 -31.673 -42.544 1.000 34.013 0 458  VAL A HG12 1 c 
ATOM   7166 H HG13 . VAL A 1 431 ? -21.773 -30.294 -42.406 1.000 34.035 0 458  VAL A HG13 1 c 
ATOM   7167 H HG21 . VAL A 1 431 ? -20.626 -28.348 -41.674 1.000 33.023 0 458  VAL A HG21 1 c 
ATOM   7168 H HG22 . VAL A 1 431 ? -19.101 -28.134 -42.048 1.000 32.899 0 458  VAL A HG22 1 c 
ATOM   7169 H HG23 . VAL A 1 431 ? -19.491 -28.861 -40.693 1.000 32.883 0 458  VAL A HG23 1 c 
ATOM   7170 N N    . SER A 1 432 ? -16.669 -30.142 -43.270 1.000 31.230 0 459  SER A N    1 ? 
ATOM   7171 C CA   . SER A 1 432 ? -15.417 -29.500 -43.595 1.000 33.598 0 459  SER A CA   1 ? 
ATOM   7172 C C    . SER A 1 432 ? -15.671 -28.166 -44.289 1.000 39.392 0 459  SER A C    1 ? 
ATOM   7173 O O    . SER A 1 432 ? -16.680 -28.010 -44.978 1.000 43.926 0 459  SER A O    1 ? 
ATOM   7174 C CB   . SER A 1 432 ? -14.600 -30.423 -44.466 1.000 37.175 0 459  SER A CB   1 ? 
ATOM   7175 O OG   . SER A 1 432 ? -14.815 -31.782 -44.112 1.000 39.418 0 459  SER A OG   1 ? 
ATOM   7176 H H    . SER A 1 432 ? -17.089 -30.618 -43.928 1.000 31.278 0 459  SER A H    1 c 
ATOM   7177 H HA   . SER A 1 432 ? -14.921 -29.334 -42.756 1.000 34.692 0 459  SER A HA   1 c 
ATOM   7178 H HB2  . SER A 1 432 ? -14.843 -30.288 -45.402 1.000 36.857 0 459  SER A HB2  1 c 
ATOM   7179 H HB3  . SER A 1 432 ? -13.657 -30.209 -44.361 1.000 36.842 0 459  SER A HB3  1 c 
ATOM   7180 H HG   . SER A 1 432 ? -14.356 -32.277 -44.621 0.000 39.490 0 459  SER A HG   1 c 
ATOM   7181 N N    . VAL A 1 433 ? -14.761 -27.213 -44.068 1.000 41.667 0 460  VAL A N    1 ? 
ATOM   7182 C CA   . VAL A 1 433 ? -14.606 -26.039 -44.914 1.000 47.426 0 460  VAL A CA   1 ? 
ATOM   7183 C C    . VAL A 1 433 ? -13.397 -26.281 -45.843 1.000 41.820 0 460  VAL A C    1 ? 
ATOM   7184 O O    . VAL A 1 433 ? -13.644 -26.581 -47.044 1.000 44.644 0 460  VAL A O    1 ? 
ATOM   7185 C CB   . VAL A 1 433 ? -14.436 -24.756 -44.070 1.000 45.102 0 460  VAL A CB   1 ? 
ATOM   7186 H H    . VAL A 1 433 ? -14.207 -27.299 -43.346 1.000 42.199 0 460  VAL A H    1 c 
ATOM   7187 H HA   . VAL A 1 433 ? -15.407 -25.943 -45.465 1.000 44.743 0 460  VAL A HA   1 c 
ATOM   7188 H HB   . VAL A 1 433 ? -14.398 -24.001 -44.698 0.000 45.190 0 460  VAL A HB   1 c 
ATOM   7189 N N    . PRO A 1 445 ? -27.704 -32.076 -36.342 1.000 27.945 0 549  PRO A N    1 ? 
ATOM   7190 C CA   . PRO A 1 445 ? -26.624 -31.385 -35.632 1.000 25.685 0 549  PRO A CA   1 ? 
ATOM   7191 C C    . PRO A 1 445 ? -25.338 -31.383 -36.470 1.000 24.008 0 549  PRO A C    1 ? 
ATOM   7192 O O    . PRO A 1 445 ? -24.946 -32.422 -37.016 1.000 22.579 0 549  PRO A O    1 ? 
ATOM   7193 C CB   . PRO A 1 445 ? -26.492 -32.103 -34.263 1.000 31.796 0 549  PRO A CB   1 ? 
ATOM   7194 C CG   . PRO A 1 445 ? -27.435 -33.256 -34.376 1.000 30.855 0 549  PRO A CG   1 ? 
ATOM   7195 C CD   . PRO A 1 445 ? -28.467 -32.883 -35.418 1.000 32.989 0 549  PRO A CD   1 ? 
ATOM   7196 H H    . PRO A 1 445 ? -27.855 -32.004 -37.185 1.000 28.477 0 549  PRO A H    1 c 
ATOM   7197 H HA   . PRO A 1 445 ? -26.911 -30.451 -35.476 1.000 26.800 0 549  PRO A HA   1 c 
ATOM   7198 H HB2  . PRO A 1 445 ? -25.568 -32.416 -34.115 1.000 30.093 0 549  PRO A HB2  1 c 
ATOM   7199 H HB3  . PRO A 1 445 ? -26.752 -31.505 -33.524 1.000 30.124 0 549  PRO A HB3  1 c 
ATOM   7200 H HG2  . PRO A 1 445 ? -26.955 -34.065 -34.647 1.000 31.397 0 549  PRO A HG2  1 c 
ATOM   7201 H HG3  . PRO A 1 445 ? -27.868 -33.428 -33.515 1.000 31.345 0 549  PRO A HG3  1 c 
ATOM   7202 H HD2  . PRO A 1 445 ? -28.830 -33.682 -35.860 1.000 31.253 0 549  PRO A HD2  1 c 
ATOM   7203 H HD3  . PRO A 1 445 ? -29.203 -32.368 -35.019 1.000 31.253 0 549  PRO A HD3  1 c 
ATOM   7204 N N    . VAL A 1 446 ? -24.752 -30.188 -36.677 1.000 26.771 0 550  VAL A N    1 ? 
ATOM   7205 C CA   . VAL A 1 446 ? -23.616 -30.023 -37.570 1.000 25.953 0 550  VAL A CA   1 ? 
ATOM   7206 C C    . VAL A 1 446 ? -22.528 -29.228 -36.838 1.000 26.885 0 550  VAL A C    1 ? 
ATOM   7207 O O    . VAL A 1 446 ? -22.791 -28.270 -36.105 1.000 31.211 0 550  VAL A O    1 ? 
ATOM   7208 C CB   . VAL A 1 446 ? -23.883 -29.316 -38.916 1.000 29.046 0 550  VAL A CB   1 ? 
ATOM   7209 C CG1  . VAL A 1 446 ? -24.836 -30.087 -39.817 1.000 28.728 0 550  VAL A CG1  1 ? 
ATOM   7210 C CG2  . VAL A 1 446 ? -24.370 -27.889 -38.677 1.000 32.837 0 550  VAL A CG2  1 ? 
ATOM   7211 H H    . VAL A 1 446 ? -25.073 -29.453 -36.239 1.000 25.955 0 550  VAL A H    1 c 
ATOM   7212 H HA   . VAL A 1 446 ? -23.261 -30.909 -37.765 1.000 26.612 0 550  VAL A HA   1 c 
ATOM   7213 H HB   . VAL A 1 446 ? -23.018 -29.257 -39.386 1.000 29.035 0 550  VAL A HB   1 c 
ATOM   7214 H HG11 . VAL A 1 446 ? -25.688 -30.205 -39.364 1.000 28.817 0 550  VAL A HG11 1 c 
ATOM   7215 H HG12 . VAL A 1 446 ? -24.457 -30.958 -40.023 1.000 28.789 0 550  VAL A HG12 1 c 
ATOM   7216 H HG13 . VAL A 1 446 ? -24.975 -29.593 -40.643 1.000 28.831 0 550  VAL A HG13 1 c 
ATOM   7217 H HG21 . VAL A 1 446 ? -24.768 -27.541 -39.493 1.000 31.610 0 550  VAL A HG21 1 c 
ATOM   7218 H HG22 . VAL A 1 446 ? -23.620 -27.326 -38.420 1.000 31.617 0 550  VAL A HG22 1 c 
ATOM   7219 H HG23 . VAL A 1 446 ? -25.035 -27.886 -37.968 1.000 31.584 0 550  VAL A HG23 1 c 
ATOM   7220 N N    . LEU A 1 447 ? -21.279 -29.633 -37.074 1.000 19.296 0 551  LEU A N    1 ? 
ATOM   7221 C CA   . LEU A 1 447 ? -20.143 -28.987 -36.434 1.000 19.388 0 551  LEU A CA   1 ? 
ATOM   7222 C C    . LEU A 1 447 ? -19.013 -28.918 -37.454 1.000 15.026 0 551  LEU A C    1 ? 
ATOM   7223 O O    . LEU A 1 447 ? -18.748 -29.873 -38.187 1.000 16.230 0 551  LEU A O    1 ? 
ATOM   7224 C CB   . LEU A 1 447 ? -19.739 -29.835 -35.230 1.000 20.322 0 551  LEU A CB   1 ? 
ATOM   7225 C CG   . LEU A 1 447 ? -18.597 -29.269 -34.391 1.000 21.182 0 551  LEU A CG   1 ? 
ATOM   7226 C CD1  . LEU A 1 447 ? -18.886 -27.906 -33.827 1.000 22.965 0 551  LEU A CD1  1 ? 
ATOM   7227 C CD2  . LEU A 1 447 ? -18.319 -30.260 -33.286 1.000 23.459 0 551  LEU A CD2  1 ? 
ATOM   7228 H H    . LEU A 1 447 ? -21.128 -30.328 -37.648 1.000 20.947 0 551  LEU A H    1 c 
ATOM   7229 H HA   . LEU A 1 447 ? -20.399 -28.076 -36.144 1.000 18.737 0 551  LEU A HA   1 c 
ATOM   7230 H HB2  . LEU A 1 447 ? -20.528 -29.944 -34.651 1.000 20.301 0 551  LEU A HB2  1 c 
ATOM   7231 H HB3  . LEU A 1 447 ? -19.476 -30.727 -35.556 1.000 20.326 0 551  LEU A HB3  1 c 
ATOM   7232 H HG   . LEU A 1 447 ? -17.788 -29.206 -34.962 1.000 21.716 0 551  LEU A HG   1 c 
ATOM   7233 H HD11 . LEU A 1 447 ? -18.924 -27.256 -34.548 1.000 22.372 0 551  LEU A HD11 1 c 
ATOM   7234 H HD12 . LEU A 1 447 ? -18.181 -27.656 -33.205 1.000 22.409 0 551  LEU A HD12 1 c 
ATOM   7235 H HD13 . LEU A 1 447 ? -19.738 -27.921 -33.360 1.000 22.407 0 551  LEU A HD13 1 c 
ATOM   7236 H HD21 . LEU A 1 447 ? -18.059 -31.114 -33.672 1.000 22.740 0 551  LEU A HD21 1 c 
ATOM   7237 H HD22 . LEU A 1 447 ? -19.120 -30.380 -32.748 1.000 22.753 0 551  LEU A HD22 1 c 
ATOM   7238 H HD23 . LEU A 1 447 ? -17.599 -29.928 -32.724 1.000 22.751 0 551  LEU A HD23 1 c 
ATOM   7239 N N    . THR A 1 448 ? -18.300 -27.790 -37.408 1.000 15.263 0 552  THR A N    1 ? 
ATOM   7240 C CA   . THR A 1 448 ? -17.074 -27.617 -38.173 1.000 14.837 0 552  THR A CA   1 ? 
ATOM   7241 C C    . THR A 1 448 ? -15.898 -27.493 -37.201 1.000 13.767 0 552  THR A C    1 ? 
ATOM   7242 O O    . THR A 1 448 ? -15.990 -26.756 -36.242 1.000 16.366 0 552  THR A O    1 ? 
ATOM   7243 C CB   . THR A 1 448 ? -17.148 -26.355 -39.038 1.000 18.099 0 552  THR A CB   1 ? 
ATOM   7244 O OG1  . THR A 1 448 ? -18.161 -26.588 -40.026 1.000 22.192 0 552  THR A OG1  1 ? 
ATOM   7245 C CG2  . THR A 1 448 ? -15.916 -26.077 -39.876 1.000 19.559 0 552  THR A CG2  1 ? 
ATOM   7246 H H    . THR A 1 448 ? -18.587 -27.100 -36.882 1.000 15.212 0 552  THR A H    1 c 
ATOM   7247 H HA   . THR A 1 448 ? -16.939 -28.398 -38.751 1.000 15.272 0 552  THR A HA   1 c 
ATOM   7248 H HB   . THR A 1 448 ? -17.384 -25.568 -38.492 1.000 18.438 0 552  THR A HB   1 c 
ATOM   7249 H HG1  . THR A 1 448 ? -17.945 -27.274 -40.504 0.000 22.200 0 552  THR A HG1  1 c 
ATOM   7250 H HG21 . THR A 1 448 ? -16.091 -25.330 -40.473 1.000 19.125 0 552  THR A HG21 1 c 
ATOM   7251 H HG22 . THR A 1 448 ? -15.695 -26.865 -40.401 1.000 19.111 0 552  THR A HG22 1 c 
ATOM   7252 H HG23 . THR A 1 448 ? -15.168 -25.856 -39.295 1.000 19.087 0 552  THR A HG23 1 c 
ATOM   7253 N N    . PHE A 1 449 ? -14.795 -28.188 -37.461 1.000 10.624 0 553  PHE A N    1 ? 
ATOM   7254 C CA   . PHE A 1 449 ? -13.609 -28.064 -36.644 1.000 9.859  0 553  PHE A CA   1 ? 
ATOM   7255 C C    . PHE A 1 449 ? -12.666 -27.031 -37.229 1.000 9.212  0 553  PHE A C    1 ? 
ATOM   7256 O O    . PHE A 1 449 ? -12.407 -27.045 -38.453 1.000 10.874 0 553  PHE A O    1 ? 
ATOM   7257 C CB   . PHE A 1 449 ? -12.932 -29.419 -36.595 1.000 9.752  0 553  PHE A CB   1 ? 
ATOM   7258 C CG   . PHE A 1 449 ? -13.566 -30.444 -35.679 1.000 9.012  0 553  PHE A CG   1 ? 
ATOM   7259 C CD1  . PHE A 1 449 ? -14.113 -30.118 -34.446 1.000 10.166 0 553  PHE A CD1  1 ? 
ATOM   7260 C CD2  . PHE A 1 449 ? -13.597 -31.784 -36.057 1.000 9.857  0 553  PHE A CD2  1 ? 
ATOM   7261 C CE1  . PHE A 1 449 ? -14.640 -31.086 -33.623 1.000 10.054 0 553  PHE A CE1  1 ? 
ATOM   7262 C CE2  . PHE A 1 449 ? -14.120 -32.762 -35.217 1.000 10.379 0 553  PHE A CE2  1 ? 
ATOM   7263 C CZ   . PHE A 1 449 ? -14.637 -32.398 -33.985 1.000 9.938  0 553  PHE A CZ   1 ? 
ATOM   7264 H H    . PHE A 1 449 ? -14.782 -28.756 -38.177 1.000 11.141 0 553  PHE A H    1 c 
ATOM   7265 H HA   . PHE A 1 449 ? -13.868 -27.791 -35.726 1.000 9.888  0 553  PHE A HA   1 c 
ATOM   7266 H HB2  . PHE A 1 449 ? -12.909 -29.785 -37.507 1.000 9.620  0 553  PHE A HB2  1 c 
ATOM   7267 H HB3  . PHE A 1 449 ? -11.999 -29.286 -36.314 1.000 9.602  0 553  PHE A HB3  1 c 
ATOM   7268 H HD1  . PHE A 1 449 ? -14.101 -29.221 -34.155 1.000 9.852  0 553  PHE A HD1  1 c 
ATOM   7269 H HD2  . PHE A 1 449 ? -13.216 -32.039 -36.882 1.000 9.777  0 553  PHE A HD2  1 c 
ATOM   7270 H HE1  . PHE A 1 449 ? -15.001 -30.836 -32.788 1.000 10.026 0 553  PHE A HE1  1 c 
ATOM   7271 H HE2  . PHE A 1 449 ? -14.129 -33.666 -35.489 1.000 10.143 0 553  PHE A HE2  1 c 
ATOM   7272 H HZ   . PHE A 1 449 ? -15.028 -33.047 -33.423 1.000 10.060 0 553  PHE A HZ   1 c 
ATOM   7273 N N    . GLN A 1 450 ? -12.046 -26.249 -36.384 1.000 8.569  0 554  GLN A N    1 ? 
ATOM   7274 C CA   . GLN A 1 450 ? -11.028 -25.300 -36.770 1.000 9.700  0 554  GLN A CA   1 ? 
ATOM   7275 C C    . GLN A 1 450 ? -9.633  -25.899 -36.571 1.000 8.843  0 554  GLN A C    1 ? 
ATOM   7276 O O    . GLN A 1 450 ? -8.699  -25.448 -37.256 1.000 10.862 0 554  GLN A O    1 ? 
ATOM   7277 C CB   . GLN A 1 450 ? -11.084 -24.037 -35.910 1.000 11.974 0 554  GLN A CB   1 ? 
ATOM   7278 C CG   . GLN A 1 450 ? -12.372 -23.238 -36.093 1.000 15.959 0 554  GLN A CG   1 ? 
ATOM   7279 C CD   . GLN A 1 450 ? -12.607 -22.854 -37.535 1.000 22.052 0 554  GLN A CD   1 ? 
ATOM   7280 O OE1  . GLN A 1 450 ? -11.674 -22.462 -38.237 1.000 26.733 0 554  GLN A OE1  1 ? 
ATOM   7281 N NE2  . GLN A 1 450 ? -13.819 -23.042 -38.018 1.000 30.029 0 554  GLN A NE2  1 ? 
ATOM   7282 H H    . GLN A 1 450 ? -12.278 -26.292 -35.502 1.000 8.986  0 554  GLN A H    1 c 
ATOM   7283 H HA   . GLN A 1 450 ? -11.148 -25.067 -37.725 1.000 9.775  0 554  GLN A HA   1 c 
ATOM   7284 H HB2  . GLN A 1 450 ? -10.999 -24.293 -34.968 1.000 12.174 0 554  GLN A HB2  1 c 
ATOM   7285 H HB3  . GLN A 1 450 ? -10.320 -23.466 -36.135 1.000 12.216 0 554  GLN A HB3  1 c 
ATOM   7286 H HG2  . GLN A 1 450 ? -13.132 -23.771 -35.775 1.000 16.238 0 554  GLN A HG2  1 c 
ATOM   7287 H HG3  . GLN A 1 450 ? -12.328 -22.423 -35.550 1.000 16.138 0 554  GLN A HG3  1 c 
ATOM   7288 H HE21 . GLN A 1 450 ? -14.518 -23.085 -37.465 1.000 27.061 0 554  GLN A HE21 1 c 
ATOM   7289 H HE22 . GLN A 1 450 ? -13.936 -23.125 -38.898 1.000 27.238 0 554  GLN A HE22 1 c 
ATOM   7290 N N    . SER A 1 451 ? -9.451  -26.847 -35.642 1.000 8.249  0 555  SER A N    1 ? 
ATOM   7291 C CA   . SER A 1 451 ? -8.140  -27.403 -35.362 1.000 8.155  0 555  SER A CA   1 ? 
ATOM   7292 C C    . SER A 1 451 ? -7.817  -28.616 -36.191 1.000 7.566  0 555  SER A C    1 ? 
ATOM   7293 O O    . SER A 1 451 ? -8.689  -29.453 -36.450 1.000 7.776  0 555  SER A O    1 ? 
ATOM   7294 C CB   . SER A 1 451 ? -8.008  -27.753 -33.878 1.000 7.927  0 555  SER A CB   1 ? 
ATOM   7295 O OG   . SER A 1 451 ? -8.659  -28.958 -33.507 1.000 7.897  0 555  SER A OG   1 ? 
ATOM   7296 H H    . SER A 1 451 ? -10.168 -27.155 -35.167 1.000 8.374  0 555  SER A H    1 c 
ATOM   7297 H HA   . SER A 1 451 ? -7.467  -26.706 -35.568 1.000 8.047  0 555  SER A HA   1 c 
ATOM   7298 H HB2  . SER A 1 451 ? -7.060  -27.826 -33.657 1.000 7.971  0 555  SER A HB2  1 c 
ATOM   7299 H HB3  . SER A 1 451 ? -8.375  -27.020 -33.349 1.000 7.971  0 555  SER A HB3  1 c 
ATOM   7300 H HG   . SER A 1 451 ? -8.543  -29.083 -32.678 0.000 7.890  0 555  SER A HG   1 c 
ATOM   7301 N N    . GLU A 1 452 ? -6.531  -28.728 -36.544 1.000 8.135  0 556  GLU A N    1 ? 
ATOM   7302 C CA   . GLU A 1 452 ? -6.120  -29.941 -37.233 1.000 7.687  0 556  GLU A CA   1 ? 
ATOM   7303 C C    . GLU A 1 452 ? -6.197  -31.185 -36.344 1.000 7.641  0 556  GLU A C    1 ? 
ATOM   7304 O O    . GLU A 1 452 ? -6.537  -32.277 -36.825 1.000 8.036  0 556  GLU A O    1 ? 
ATOM   7305 C CB   . GLU A 1 452 ? -4.730  -29.761 -37.851 1.000 8.633  0 556  GLU A CB   1 ? 
ATOM   7306 C CG   . GLU A 1 452 ? -4.699  -28.749 -38.995 1.000 10.217 0 556  GLU A CG   1 ? 
ATOM   7307 C CD   . GLU A 1 452 ? -5.649  -28.973 -40.122 1.000 9.602  0 556  GLU A CD   1 ? 
ATOM   7308 O OE1  . GLU A 1 452 ? -5.830  -30.127 -40.556 1.000 9.292  0 556  GLU A OE1  1 ? 
ATOM   7309 O OE2  . GLU A 1 452 ? -6.251  -27.961 -40.630 1.000 11.007 0 556  GLU A OE2  1 ? 
ATOM   7310 H H    . GLU A 1 452 ? -5.922  -28.071 -36.361 1.000 7.902  0 556  GLU A H    1 c 
ATOM   7311 H HA   . GLU A 1 452 ? -6.749  -30.082 -37.985 1.000 7.937  0 556  GLU A HA   1 c 
ATOM   7312 H HB2  . GLU A 1 452 ? -4.108  -29.471 -37.151 1.000 8.736  0 556  GLU A HB2  1 c 
ATOM   7313 H HB3  . GLU A 1 452 ? -4.420  -30.627 -38.185 1.000 8.731  0 556  GLU A HB3  1 c 
ATOM   7314 H HG2  . GLU A 1 452 ? -4.874  -27.857 -38.625 1.000 9.700  0 556  GLU A HG2  1 c 
ATOM   7315 H HG3  . GLU A 1 452 ? -3.790  -28.728 -39.365 1.000 9.694  0 556  GLU A HG3  1 c 
ATOM   7316 N N    . LYS A 1 453 ? -5.942  -31.040 -35.052 1.000 7.100  0 557  LYS A N    1 ? 
ATOM   7317 C CA   . LYS A 1 453 ? -6.016  -32.207 -34.205 1.000 7.665  0 557  LYS A CA   1 ? 
ATOM   7318 C C    . LYS A 1 453 ? -7.434  -32.769 -34.217 1.000 7.559  0 557  LYS A C    1 ? 
ATOM   7319 O O    . LYS A 1 453 ? -7.632  -33.988 -34.291 1.000 8.565  0 557  LYS A O    1 ? 
ATOM   7320 C CB   . LYS A 1 453 ? -5.573  -31.968 -32.766 1.000 8.829  0 557  LYS A CB   1 ? 
ATOM   7321 C CG   . LYS A 1 453 ? -4.076  -31.942 -32.609 1.000 9.225  0 557  LYS A CG   1 ? 
ATOM   7322 C CD   . LYS A 1 453 ? -3.592  -31.729 -31.185 1.000 9.694  0 557  LYS A CD   1 ? 
ATOM   7323 C CE   . LYS A 1 453 ? -2.134  -31.820 -31.080 1.000 9.649  0 557  LYS A CE   1 ? 
ATOM   7324 N NZ   . LYS A 1 453 ? -1.571  -31.653 -29.752 1.000 9.295  0 557  LYS A NZ   1 ? 
ATOM   7325 H H    . LYS A 1 453 ? -5.718  -30.228 -34.696 1.000 7.358  0 557  LYS A H    1 c 
ATOM   7326 H HA   . LYS A 1 453 ? -5.414  -32.895 -34.587 1.000 7.749  0 557  LYS A HA   1 c 
ATOM   7327 H HB2  . LYS A 1 453 ? -5.938  -31.111 -32.456 1.000 8.636  0 557  LYS A HB2  1 c 
ATOM   7328 H HB3  . LYS A 1 453 ? -5.937  -32.676 -32.194 1.000 8.631  0 557  LYS A HB3  1 c 
ATOM   7329 H HG2  . LYS A 1 453 ? -3.716  -32.792 -32.940 1.000 9.238  0 557  LYS A HG2  1 c 
ATOM   7330 H HG3  . LYS A 1 453 ? -3.716  -31.227 -33.176 1.000 9.247  0 557  LYS A HG3  1 c 
ATOM   7331 H HD2  . LYS A 1 453 ? -3.882  -30.843 -30.875 1.000 9.577  0 557  LYS A HD2  1 c 
ATOM   7332 H HD3  . LYS A 1 453 ? -4.000  -32.405 -30.602 1.000 9.580  0 557  LYS A HD3  1 c 
ATOM   7333 H HE2  . LYS A 1 453 ? -1.863  -32.692 -31.416 1.000 9.630  0 557  LYS A HE2  1 c 
ATOM   7334 H HE3  . LYS A 1 453 ? -1.740  -31.149 -31.665 1.000 9.585  0 557  LYS A HE3  1 c 
ATOM   7335 H HZ1  . LYS A 1 453 ? -1.832  -32.339 -29.220 1.000 9.405  0 557  LYS A HZ1  1 c 
ATOM   7336 H HZ2  . LYS A 1 453 ? -1.859  -30.873 -29.393 1.000 9.411  0 557  LYS A HZ2  1 c 
ATOM   7337 H HZ3  . LYS A 1 453 ? -0.666  -31.642 -29.801 1.000 9.405  0 557  LYS A HZ3  1 c 
ATOM   7338 N N    . MET A 1 454 ? -8.459  -31.955 -34.089 1.000 7.702  0 558  MET A N    1 ? 
ATOM   7339 C CA   . MET A 1 454 ? -9.803  -32.521 -34.071 1.000 7.571  0 558  MET A CA   1 ? 
ATOM   7340 C C    . MET A 1 454 ? -10.265 -33.034 -35.430 1.000 8.411  0 558  MET A C    1 ? 
ATOM   7341 O O    . MET A 1 454 ? -10.992 -34.037 -35.515 1.000 9.060  0 558  MET A O    1 ? 
ATOM   7342 C CB   . MET A 1 454 ? -10.841 -31.590 -33.459 1.000 7.290  0 558  MET A CB   1 ? 
ATOM   7343 C CG   . MET A 1 454 ? -10.569 -31.257 -31.988 1.000 8.358  0 558  MET A CG   1 ? 
ATOM   7344 S SD   . MET A 1 454 ? -10.540 -32.700 -30.874 1.000 8.739  0 558  MET A SD   1 ? 
ATOM   7345 C CE   . MET A 1 454 ? -12.299 -33.068 -30.852 1.000 11.026 0 558  MET A CE   1 ? 
ATOM   7346 H H    . MET A 1 454 ? -8.342  -31.052 -34.007 1.000 7.635  0 558  MET A H    1 c 
ATOM   7347 H HA   . MET A 1 454 ? -9.755  -33.322 -33.490 1.000 7.703  0 558  MET A HA   1 c 
ATOM   7348 H HB2  . MET A 1 454 ? -10.860 -30.758 -33.977 1.000 7.588  0 558  MET A HB2  1 c 
ATOM   7349 H HB3  . MET A 1 454 ? -11.724 -32.011 -33.534 1.000 7.604  0 558  MET A HB3  1 c 
ATOM   7350 H HG2  . MET A 1 454 ? -9.710  -30.796 -31.919 1.000 8.152  0 558  MET A HG2  1 c 
ATOM   7351 H HG3  . MET A 1 454 ? -11.260 -30.643 -31.673 1.000 8.134  0 558  MET A HG3  1 c 
ATOM   7352 H HE1  . MET A 1 454 ? -12.465 -33.823 -30.259 1.000 10.396 0 558  MET A HE1  1 c 
ATOM   7353 H HE2  . MET A 1 454 ? -12.790 -32.289 -30.532 1.000 10.396 0 558  MET A HE2  1 c 
ATOM   7354 H HE3  . MET A 1 454 ? -12.595 -33.291 -31.754 1.000 10.378 0 558  MET A HE3  1 c 
ATOM   7355 N N    . LYS A 1 455 ? -9.822  -32.383 -36.517 1.000 8.241  0 559  LYS A N    1 ? 
ATOM   7356 C CA   . LYS A 1 455 ? -10.131 -32.903 -37.857 1.000 8.853  0 559  LYS A CA   1 ? 
ATOM   7357 C C    . LYS A 1 455 ? -9.614  -34.345 -37.993 1.000 8.983  0 559  LYS A C    1 ? 
ATOM   7358 O O    . LYS A 1 455 ? -10.298 -35.206 -38.589 1.000 10.681 0 559  LYS A O    1 ? 
ATOM   7359 C CB   . LYS A 1 455 ? -9.560  -32.039 -38.984 1.000 8.859  0 559  LYS A CB   1 ? 
ATOM   7360 C CG   . LYS A 1 455 ? -10.179 -30.674 -39.120 1.000 9.015  0 559  LYS A CG   1 ? 
ATOM   7361 C CD   . LYS A 1 455 ? -9.367  -29.826 -40.085 1.000 9.681  0 559  LYS A CD   1 ? 
ATOM   7362 C CE   . LYS A 1 455 ? -9.833  -28.398 -40.099 1.000 9.798  0 559  LYS A CE   1 ? 
ATOM   7363 N NZ   . LYS A 1 455 ? -9.109  -27.677 -41.153 1.000 11.034 0 559  LYS A NZ   1 ? 
ATOM   7364 H H    . LYS A 1 455 ? -9.336  -31.614 -36.434 1.000 8.406  0 559  LYS A H    1 c 
ATOM   7365 H HA   . LYS A 1 455 ? -11.117 -32.919 -37.956 1.000 8.757  0 559  LYS A HA   1 c 
ATOM   7366 H HB2  . LYS A 1 455 ? -8.597  -31.929 -38.834 1.000 8.902  0 559  LYS A HB2  1 c 
ATOM   7367 H HB3  . LYS A 1 455 ? -9.675  -32.516 -39.833 1.000 8.896  0 559  LYS A HB3  1 c 
ATOM   7368 H HG2  . LYS A 1 455 ? -11.097 -30.768 -39.455 1.000 9.123  0 559  LYS A HG2  1 c 
ATOM   7369 H HG3  . LYS A 1 455 ? -10.207 -30.241 -38.241 1.000 9.116  0 559  LYS A HG3  1 c 
ATOM   7370 H HD2  . LYS A 1 455 ? -8.421  -29.853 -39.824 1.000 9.548  0 559  LYS A HD2  1 c 
ATOM   7371 H HD3  . LYS A 1 455 ? -9.447  -30.201 -40.990 1.000 9.558  0 559  LYS A HD3  1 c 
ATOM   7372 H HE2  . LYS A 1 455 ? -10.790 -28.359 -40.277 1.000 10.049 0 559  LYS A HE2  1 c 
ATOM   7373 H HE3  . LYS A 1 455 ? -9.656  -27.979 -39.238 1.000 10.049 0 559  LYS A HE3  1 c 
ATOM   7374 H HZ1  . LYS A 1 455 ? -9.200  -28.104 -41.945 1.000 10.624 0 559  LYS A HZ1  1 c 
ATOM   7375 H HZ2  . LYS A 1 455 ? -8.229  -27.632 -40.941 1.000 10.634 0 559  LYS A HZ2  1 c 
ATOM   7376 H HZ3  . LYS A 1 455 ? -9.439  -26.837 -41.229 1.000 10.634 0 559  LYS A HZ3  1 c 
ATOM   7377 N N    . GLY A 1 456 ? -8.424  -34.637 -37.481 1.000 9.428  0 560  GLY A N    1 ? 
ATOM   7378 C CA   . GLY A 1 456 ? -7.892  -35.994 -37.619 1.000 10.549 0 560  GLY A CA   1 ? 
ATOM   7379 C C    . GLY A 1 456 ? -8.547  -36.966 -36.656 1.000 13.172 0 560  GLY A C    1 ? 
ATOM   7380 O O    . GLY A 1 456 ? -8.482  -38.167 -36.864 1.000 14.285 0 560  GLY A O    1 ? 
ATOM   7381 H H    . GLY A 1 456 ? -7.931  -34.000 -37.048 1.000 9.541  0 560  GLY A H    1 c 
ATOM   7382 H HA2  . GLY A 1 456 ? -8.033  -36.303 -38.545 1.000 10.787 0 560  GLY A HA2  1 c 
ATOM   7383 H HA3  . GLY A 1 456 ? -6.921  -35.974 -37.453 1.000 10.793 0 560  GLY A HA3  1 c 
ATOM   7384 N N    A MET A 1 457 ? -9.262  -36.471 -35.642 0.500 11.847 0 561  MET A N    1 ? 
ATOM   7385 N N    B MET A 1 457 ? -9.178  -36.416 -35.612 0.500 13.790 0 561  MET A N    1 ? 
ATOM   7386 C CA   A MET A 1 457 ? -9.912  -37.339 -34.664 0.500 11.796 0 561  MET A CA   1 ? 
ATOM   7387 C CA   B MET A 1 457 ? -9.901  -37.165 -34.594 0.500 15.520 0 561  MET A CA   1 ? 
ATOM   7388 C C    A MET A 1 457 ? -11.314 -37.726 -35.128 0.500 12.617 0 561  MET A C    1 ? 
ATOM   7389 C C    B MET A 1 457 ? -11.254 -37.671 -35.095 0.500 14.363 0 561  MET A C    1 ? 
ATOM   7390 O O    A MET A 1 457 ? -11.973 -38.612 -34.560 0.500 12.147 0 561  MET A O    1 ? 
ATOM   7391 O O    B MET A 1 457 ? -11.818 -38.572 -34.460 0.500 14.181 0 561  MET A O    1 ? 
ATOM   7392 C CB   A MET A 1 457 ? -9.960  -36.647 -33.288 0.500 10.812 0 561  MET A CB   1 ? 
ATOM   7393 C CB   B MET A 1 457 ? -10.157 -36.259 -33.379 0.500 17.699 0 561  MET A CB   1 ? 
ATOM   7394 C CG   A MET A 1 457 ? -9.850  -37.594 -32.098 0.500 10.079 0 561  MET A CG   1 ? 
ATOM   7395 C CG   B MET A 1 457 ? -10.450 -36.957 -32.079 0.500 20.505 0 561  MET A CG   1 ? 
ATOM   7396 S SD   A MET A 1 457 ? -10.100 -36.617 -30.599 0.500 10.790 0 561  MET A SD   1 ? 
ATOM   7397 S SD   B MET A 1 457 ? -8.902  -37.528 -31.364 0.500 21.463 0 561  MET A SD   1 ? 
ATOM   7398 C CE   A MET A 1 457 ? -8.454  -35.914 -30.457 0.500 11.229 0 561  MET A CE   1 ? 
ATOM   7399 C CE   B MET A 1 457 ? -8.174  -36.098 -30.554 0.500 21.576 0 561  MET A CE   1 ? 
ATOM   7400 H H    A MET A 1 457 ? -9.337  -35.567 -35.542 0.500 12.057 0 561  MET A H    1 c 
ATOM   7401 H H    B MET A 1 457 ? -9.136  -35.509 -35.516 0.500 13.861 0 561  MET A H    1 c 
ATOM   7402 H HA   A MET A 1 457 ? -9.376  -38.168 -34.585 0.500 11.788 0 561  MET A HA   1 c 
ATOM   7403 H HA   B MET A 1 457 ? -9.348  -37.941 -34.322 0.500 15.306 0 561  MET A HA   1 c 
ATOM   7404 H HB2  A MET A 1 457 ? -9.228  -35.996 -33.243 0.500 10.852 0 561  MET A HB2  1 c 
ATOM   7405 H HB2  B MET A 1 457 ? -9.370  -35.687 -33.253 0.500 17.690 0 561  MET A HB2  1 c 
ATOM   7406 H HB3  A MET A 1 457 ? -10.804 -36.151 -33.220 0.500 10.852 0 561  MET A HB3  1 c 
ATOM   7407 H HB3  B MET A 1 457 ? -10.913 -35.672 -33.590 0.500 17.691 0 561  MET A HB3  1 c 
ATOM   7408 H HG2  A MET A 1 457 ? -10.531 -38.293 -32.155 0.500 10.436 0 561  MET A HG2  1 c 
ATOM   7409 H HG2  B MET A 1 457 ? -10.889 -36.341 -31.459 0.500 19.964 0 561  MET A HG2  1 c 
ATOM   7410 H HG3  A MET A 1 457 ? -8.966  -38.013 -32.077 0.500 10.392 0 561  MET A HG3  1 c 
ATOM   7411 H HG3  B MET A 1 457 ? -11.040 -37.720 -32.234 0.500 19.964 0 561  MET A HG3  1 c 
ATOM   7412 H HE1  A MET A 1 457 ? -8.415  -35.337 -29.672 0.500 11.137 0 561  MET A HE1  1 c 
ATOM   7413 H HE1  B MET A 1 457 ? -7.309  -36.344 -30.179 0.500 21.451 0 561  MET A HE1  1 c 
ATOM   7414 H HE2  A MET A 1 457 ? -7.801  -36.632 -30.366 0.500 11.123 0 561  MET A HE2  1 c 
ATOM   7415 H HE2  B MET A 1 457 ? -8.055  -35.382 -31.204 0.500 21.523 0 561  MET A HE2  1 c 
ATOM   7416 H HE3  A MET A 1 457 ? -8.255  -35.391 -31.255 0.500 11.123 0 561  MET A HE3  1 c 
ATOM   7417 H HE3  B MET A 1 457 ? -8.765  -35.794 -29.840 0.500 21.523 0 561  MET A HE3  1 c 
ATOM   7418 N N    . LYS A 1 458 ? -11.817 -37.047 -36.158 1.000 13.308 0 562  LYS A N    1 ? 
ATOM   7419 C CA   . LYS A 1 458 ? -13.200 -37.194 -36.578 1.000 15.831 0 562  LYS A CA   1 ? 
ATOM   7420 C C    . LYS A 1 458 ? -13.605 -38.660 -36.695 1.000 19.303 0 562  LYS A C    1 ? 
ATOM   7421 O O    . LYS A 1 458 ? -14.616 -39.066 -36.131 1.000 16.940 0 562  LYS A O    1 ? 
ATOM   7422 C CB   . LYS A 1 458 ? -13.467 -36.420 -37.883 1.000 20.390 0 562  LYS A CB   1 ? 
ATOM   7423 C CG   . LYS A 1 458 ? -14.795 -36.697 -38.539 1.000 24.461 0 562  LYS A CG   1 ? 
ATOM   7424 H H    . LYS A 1 458 ? -11.288 -36.478 -36.638 1.000 13.842 0 562  LYS A H    1 c 
ATOM   7425 H HA   . LYS A 1 458 ? -13.768 -36.782 -35.878 1.000 16.633 0 562  LYS A HA   1 c 
ATOM   7426 H HB2  . LYS A 1 458 ? -13.413 -35.459 -37.692 1.000 20.080 0 562  LYS A HB2  1 c 
ATOM   7427 H HB3  . LYS A 1 458 ? -12.756 -36.634 -38.524 1.000 20.040 0 562  LYS A HB3  1 c 
ATOM   7428 H HG2  . LYS A 1 458 ? -14.754 -37.586 -38.954 1.000 23.281 0 562  LYS A HG2  1 c 
ATOM   7429 H HG3  . LYS A 1 458 ? -15.507 -36.481 -37.920 0.000 24.490 0 562  LYS A HG3  1 c 
ATOM   7430 N N    . GLU A 1 459 ? -12.820 -39.469 -37.404 1.000 20.426 0 563  GLU A N    1 ? 
ATOM   7431 C CA   . GLU A 1 459 ? -13.297 -40.810 -37.691 1.000 27.368 0 563  GLU A CA   1 ? 
ATOM   7432 C C    . GLU A 1 459 ? -13.190 -41.730 -36.478 1.000 21.518 0 563  GLU A C    1 ? 
ATOM   7433 O O    . GLU A 1 459 ? -13.526 -42.897 -36.623 1.000 26.140 0 563  GLU A O    1 ? 
ATOM   7434 C CB   . GLU A 1 459 ? -12.584 -41.483 -38.864 1.000 34.887 0 563  GLU A CB   1 ? 
ATOM   7435 C CG   . GLU A 1 459 ? -12.570 -40.646 -40.142 1.000 46.467 0 563  GLU A CG   1 ? 
ATOM   7436 C CD   . GLU A 1 459 ? -13.899 -40.545 -40.876 1.000 54.950 0 563  GLU A CD   1 ? 
ATOM   7437 O OE1  . GLU A 1 459 ? -14.864 -41.207 -40.433 1.000 65.375 0 563  GLU A OE1  1 ? 
ATOM   7438 O OE2  . GLU A 1 459 ? -13.976 -39.816 -41.894 1.000 61.909 0 563  GLU A OE2  1 ? 
ATOM   7439 H H    . GLU A 1 459 ? -12.000 -39.198 -37.703 1.000 21.645 0 563  GLU A H    1 c 
ATOM   7440 H HA   . GLU A 1 459 ? -14.255 -40.743 -37.935 1.000 25.914 0 563  GLU A HA   1 c 
ATOM   7441 H HB2  . GLU A 1 459 ? -11.663 -41.682 -38.605 1.000 35.149 0 563  GLU A HB2  1 c 
ATOM   7442 H HB3  . GLU A 1 459 ? -13.029 -42.335 -39.055 1.000 35.299 0 563  GLU A HB3  1 c 
ATOM   7443 H HG2  . GLU A 1 459 ? -12.269 -39.739 -39.925 1.000 44.775 0 563  GLU A HG2  1 c 
ATOM   7444 H HG3  . GLU A 1 459 ? -11.912 -41.028 -40.757 1.000 45.141 0 563  GLU A HG3  1 c 
ATOM   7445 N N    . LEU A 1 460 ? -12.628 -41.295 -35.355 1.000 15.217 0 564  LEU A N    1 ? 
ATOM   7446 C CA   . LEU A 1 460 ? -12.632 -42.044 -34.113 1.000 15.750 0 564  LEU A CA   1 ? 
ATOM   7447 C C    . LEU A 1 460 ? -13.872 -41.735 -33.264 1.000 15.802 0 564  LEU A C    1 ? 
ATOM   7448 O O    . LEU A 1 460 ? -14.130 -42.401 -32.247 1.000 15.649 0 564  LEU A O    1 ? 
ATOM   7449 C CB   . LEU A 1 460 ? -11.374 -41.732 -33.314 1.000 15.438 0 564  LEU A CB   1 ? 
ATOM   7450 C CG   . LEU A 1 460 ? -10.022 -42.026 -33.991 1.000 17.136 0 564  LEU A CG   1 ? 
ATOM   7451 C CD1  . LEU A 1 460 ? -8.921  -41.547 -33.083 1.000 18.595 0 564  LEU A CD1  1 ? 
ATOM   7452 C CD2  . LEU A 1 460 ? -9.860  -43.529 -34.258 1.000 17.914 0 564  LEU A CD2  1 ? 
ATOM   7453 H H    . LEU A 1 460 ? -12.201 -40.488 -35.365 1.000 16.725 0 564  LEU A H    1 c 
ATOM   7454 H HA   . LEU A 1 460 ? -12.640 -43.009 -34.333 1.000 15.695 0 564  LEU A HA   1 c 
ATOM   7455 H HB2  . LEU A 1 460 ? -11.396 -40.778 -33.070 1.000 15.861 0 564  LEU A HB2  1 c 
ATOM   7456 H HB3  . LEU A 1 460 ? -11.414 -42.243 -32.473 1.000 15.875 0 564  LEU A HB3  1 c 
ATOM   7457 H HG   . LEU A 1 460 ? -9.976  -41.533 -34.849 1.000 17.266 0 564  LEU A HG   1 c 
ATOM   7458 H HD11 . LEU A 1 460 ? -8.931  -40.576 -33.044 1.000 18.143 0 564  LEU A HD11 1 c 
ATOM   7459 H HD12 . LEU A 1 460 ? -8.063  -41.848 -33.426 1.000 18.141 0 564  LEU A HD12 1 c 
ATOM   7460 H HD13 . LEU A 1 460 ? -9.056  -41.908 -32.191 1.000 18.130 0 564  LEU A HD13 1 c 
ATOM   7461 H HD21 . LEU A 1 460 ? -10.524 -43.818 -34.906 1.000 17.659 0 564  LEU A HD21 1 c 
ATOM   7462 H HD22 . LEU A 1 460 ? -9.982  -44.021 -33.429 1.000 17.678 0 564  LEU A HD22 1 c 
ATOM   7463 H HD23 . LEU A 1 460 ? -8.970  -43.703 -34.609 1.000 17.680 0 564  LEU A HD23 1 c 
ATOM   7464 N N    . LEU A 1 461 ? -14.597 -40.673 -33.626 1.000 15.309 0 565  LEU A N    1 ? 
ATOM   7465 C CA   . LEU A 1 461 ? -15.608 -40.161 -32.688 1.000 15.232 0 565  LEU A CA   1 ? 
ATOM   7466 C C    . LEU A 1 461 ? -16.923 -40.935 -32.676 1.000 18.462 0 565  LEU A C    1 ? 
ATOM   7467 O O    . LEU A 1 461 ? -17.685 -40.587 -31.765 1.000 17.632 0 565  LEU A O    1 ? 
ATOM   7468 C CB   . LEU A 1 461 ? -15.882 -38.695 -33.020 1.000 17.168 0 565  LEU A CB   1 ? 
ATOM   7469 C CG   . LEU A 1 461 ? -14.692 -37.801 -32.737 1.000 14.754 0 565  LEU A CG   1 ? 
ATOM   7470 C CD1  . LEU A 1 461 ? -14.983 -36.362 -33.200 1.000 17.709 0 565  LEU A CD1  1 ? 
ATOM   7471 C CD2  . LEU A 1 461 ? -14.098 -37.786 -31.369 1.000 17.100 0 565  LEU A CD2  1 ? 
ATOM   7472 H H    . LEU A 1 461 ? -14.479 -40.266 -34.435 1.000 15.471 0 565  LEU A H    1 c 
ATOM   7473 H HA   . LEU A 1 461 ? -15.227 -40.211 -31.775 1.000 16.151 0 565  LEU A HA   1 c 
ATOM   7474 H HB2  . LEU A 1 461 ? -16.111 -38.626 -33.976 1.000 16.142 0 565  LEU A HB2  1 c 
ATOM   7475 H HB3  . LEU A 1 461 ? -16.645 -38.385 -32.481 1.000 16.159 0 565  LEU A HB3  1 c 
ATOM   7476 H HG   . LEU A 1 461 ? -13.966 -38.120 -33.326 1.000 16.113 0 565  LEU A HG   1 c 
ATOM   7477 H HD11 . LEU A 1 461 ? -15.685 -35.979 -32.648 1.000 16.788 0 565  LEU A HD11 1 c 
ATOM   7478 H HD12 . LEU A 1 461 ? -15.271 -36.371 -34.128 1.000 16.787 0 565  LEU A HD12 1 c 
ATOM   7479 H HD13 . LEU A 1 461 ? -14.177 -35.824 -33.117 1.000 16.786 0 565  LEU A HD13 1 c 
ATOM   7480 H HD21 . LEU A 1 461 ? -14.792 -37.598 -30.715 1.000 16.359 0 565  LEU A HD21 1 c 
ATOM   7481 H HD22 . LEU A 1 461 ? -13.412 -37.099 -31.319 1.000 16.367 0 565  LEU A HD22 1 c 
ATOM   7482 H HD23 . LEU A 1 461 ? -13.701 -38.652 -31.177 1.000 16.353 0 565  LEU A HD23 1 c 
ATOM   7483 N N    . VAL A 1 462 ? -17.220 -41.915 -33.571 1.000 20.895 0 566  VAL A N    1 ? 
ATOM   7484 C CA   . VAL A 1 462 ? -18.542 -42.568 -33.671 1.000 22.754 0 566  VAL A CA   1 ? 
ATOM   7485 C C    . VAL A 1 462 ? -18.537 -44.081 -33.413 1.000 25.909 0 566  VAL A C    1 ? 
ATOM   7486 O O    . VAL A 1 462 ? -19.593 -44.721 -33.455 1.000 24.858 0 566  VAL A O    1 ? 
ATOM   7487 C CB   . VAL A 1 462 ? -19.222 -42.282 -35.017 1.000 24.565 0 566  VAL A CB   1 ? 
ATOM   7488 C CG1  . VAL A 1 462 ? -19.330 -40.771 -35.225 1.000 22.674 0 566  VAL A CG1  1 ? 
ATOM   7489 C CG2  . VAL A 1 462 ? -18.516 -42.947 -36.195 1.000 25.775 0 566  VAL A CG2  1 ? 
ATOM   7490 H H    . VAL A 1 462 ? -16.567 -42.180 -34.152 1.000 20.669 0 566  VAL A H    1 c 
ATOM   7491 H HA   . VAL A 1 462 ? -19.106 -42.168 -32.982 1.000 23.110 0 566  VAL A HA   1 c 
ATOM   7492 H HB   . VAL A 1 462 ? -20.137 -42.646 -34.966 1.000 24.038 0 566  VAL A HB   1 c 
ATOM   7493 H HG11 . VAL A 1 462 ? -18.441 -40.390 -35.317 1.000 23.200 0 566  VAL A HG11 1 c 
ATOM   7494 H HG12 . VAL A 1 462 ? -19.777 -40.369 -34.462 1.000 23.211 0 566  VAL A HG12 1 c 
ATOM   7495 H HG13 . VAL A 1 462 ? -19.843 -40.591 -36.031 1.000 23.211 0 566  VAL A HG13 1 c 
ATOM   7496 H HG21 . VAL A 1 462 ? -18.936 -42.665 -37.025 1.000 25.407 0 566  VAL A HG21 1 c 
ATOM   7497 H HG22 . VAL A 1 462 ? -18.581 -43.913 -36.113 1.000 25.409 0 566  VAL A HG22 1 c 
ATOM   7498 H HG23 . VAL A 1 462 ? -17.580 -42.685 -36.203 1.000 25.384 0 566  VAL A HG23 1 c 
ATOM   7499 N N    . ALA A 1 463 ? -17.367 -44.664 -33.133 1.000 24.407 0 567  ALA A N    1 ? 
ATOM   7500 C CA   . ALA A 1 463 ? -17.289 -46.079 -32.821 1.000 24.997 0 567  ALA A CA   1 ? 
ATOM   7501 C C    . ALA A 1 463 ? -17.986 -46.366 -31.502 1.000 24.551 0 567  ALA A C    1 ? 
ATOM   7502 O O    . ALA A 1 463 ? -17.922 -45.558 -30.562 1.000 21.810 0 567  ALA A O    1 ? 
ATOM   7503 C CB   . ALA A 1 463 ? -15.842 -46.502 -32.757 1.000 23.261 0 567  ALA A CB   1 ? 
ATOM   7504 H H    . ALA A 1 463 ? -16.599 -44.170 -33.134 1.000 24.792 0 567  ALA A H    1 c 
ATOM   7505 H HA   . ALA A 1 463 ? -17.751 -46.588 -33.544 1.000 24.470 0 567  ALA A HA   1 c 
ATOM   7506 H HB1  . ALA A 1 463 ? -15.415 -46.336 -33.614 1.000 23.763 0 567  ALA A HB1  1 c 
ATOM   7507 H HB2  . ALA A 1 463 ? -15.383 -45.994 -32.067 1.000 23.763 0 567  ALA A HB2  1 c 
ATOM   7508 H HB3  . ALA A 1 463 ? -15.786 -47.449 -32.548 1.000 23.763 0 567  ALA A HB3  1 c 
ATOM   7509 N N    . THR A 1 464 ? -18.651 -47.535 -31.447 1.000 22.680 0 568  THR A N    1 ? 
ATOM   7510 C CA   . THR A 1 464 ? -19.414 -47.932 -30.278 1.000 26.360 0 568  THR A CA   1 ? 
ATOM   7511 C C    . THR A 1 464 ? -18.495 -47.916 -29.066 1.000 24.017 0 568  THR A C    1 ? 
ATOM   7512 O O    . THR A 1 464 ? -18.879 -47.462 -27.991 1.000 25.521 0 568  THR A O    1 ? 
ATOM   7513 C CB   . THR A 1 464 ? -20.011 -49.325 -30.519 1.000 31.592 0 568  THR A CB   1 ? 
ATOM   7514 O OG1  . THR A 1 464 ? -21.010 -49.058 -31.497 1.000 35.020 0 568  THR A OG1  1 ? 
ATOM   7515 C CG2  . THR A 1 464 ? -20.613 -49.956 -29.272 1.000 35.952 0 568  THR A CG2  1 ? 
ATOM   7516 H H    . THR A 1 464 ? -18.623 -48.099 -32.166 1.000 24.024 0 568  THR A H    1 c 
ATOM   7517 H HA   . THR A 1 464 ? -20.143 -47.288 -30.140 1.000 26.055 0 568  THR A HA   1 c 
ATOM   7518 H HB   . THR A 1 464 ? -19.328 -49.927 -30.900 1.000 31.887 0 568  THR A HB   1 c 
ATOM   7519 H HG1  . THR A 1 464 ? -21.583 -48.492 -31.187 0.000 35.030 0 568  THR A HG1  1 c 
ATOM   7520 H HG21 . THR A 1 464 ? -21.121 -50.747 -29.522 1.000 34.589 0 568  THR A HG21 1 c 
ATOM   7521 H HG22 . THR A 1 464 ? -21.202 -49.317 -28.837 1.000 34.589 0 568  THR A HG22 1 c 
ATOM   7522 H HG23 . THR A 1 464 ? -19.902 -50.211 -28.659 1.000 34.538 0 568  THR A HG23 1 c 
ATOM   7523 N N    . LYS A 1 465 ? -17.302 -48.516 -29.248 1.000 27.119 0 569  LYS A N    1 ? 
ATOM   7524 C CA   . LYS A 1 465 ? -16.228 -48.491 -28.262 1.000 28.570 0 569  LYS A CA   1 ? 
ATOM   7525 C C    . LYS A 1 465 ? -15.099 -47.641 -28.838 1.000 27.942 0 569  LYS A C    1 ? 
ATOM   7526 O O    . LYS A 1 465 ? -14.531 -47.946 -29.883 1.000 31.330 0 569  LYS A O    1 ? 
ATOM   7527 C CB   . LYS A 1 465 ? -15.803 -49.923 -27.917 1.000 35.667 0 569  LYS A CB   1 ? 
ATOM   7528 C CG   . LYS A 1 465 ? -14.499 -50.089 -27.151 1.000 44.100 0 569  LYS A CG   1 ? 
ATOM   7529 C CD   . LYS A 1 465 ? -14.509 -49.625 -25.701 1.000 51.237 0 569  LYS A CD   1 ? 
ATOM   7530 C CE   . LYS A 1 465 ? -13.432 -50.338 -24.934 1.000 55.367 0 569  LYS A CE   1 ? 
ATOM   7531 N NZ   . LYS A 1 465 ? -13.446 -49.944 -23.524 1.000 60.901 0 569  LYS A NZ   1 ? 
ATOM   7532 H H    . LYS A 1 465 ? -17.158 -48.972 -30.027 1.000 26.626 0 569  LYS A H    1 c 
ATOM   7533 H HA   . LYS A 1 465 ? -16.567 -48.058 -27.438 1.000 29.181 0 569  LYS A HA   1 c 
ATOM   7534 H HB2  . LYS A 1 465 ? -16.519 -50.335 -27.388 1.000 35.605 0 569  LYS A HB2  1 c 
ATOM   7535 H HB3  . LYS A 1 465 ? -15.729 -50.431 -28.753 1.000 35.593 0 569  LYS A HB3  1 c 
ATOM   7536 H HG2  . LYS A 1 465 ? -14.255 -51.040 -27.173 1.000 43.574 0 569  LYS A HG2  1 c 
ATOM   7537 H HG3  . LYS A 1 465 ? -13.795 -49.602 -27.631 1.000 43.386 0 569  LYS A HG3  1 c 
ATOM   7538 H HD2  . LYS A 1 465 ? -14.350 -48.656 -25.663 1.000 50.422 0 569  LYS A HD2  1 c 
ATOM   7539 H HD3  . LYS A 1 465 ? -15.382 -49.819 -25.297 1.000 50.422 0 569  LYS A HD3  1 c 
ATOM   7540 H HE2  . LYS A 1 465 ? -13.568 -51.301 -24.994 1.000 55.549 0 569  LYS A HE2  1 c 
ATOM   7541 H HE3  . LYS A 1 465 ? -12.562 -50.126 -25.316 1.000 55.623 0 569  LYS A HE3  1 c 
ATOM   7542 H HZ1  . LYS A 1 465 ? -14.250 -50.143 -23.158 1.000 59.141 0 569  LYS A HZ1  1 c 
ATOM   7543 H HZ2  . LYS A 1 465 ? -13.300 -49.052 -23.454 1.000 59.141 0 569  LYS A HZ2  1 c 
ATOM   7544 H HZ3  . LYS A 1 465 ? -12.796 -50.388 -23.075 1.000 59.141 0 569  LYS A HZ3  1 c 
ATOM   7545 N N    . ILE A 1 466 ? -14.837 -46.530 -28.174 1.000 21.985 0 570  ILE A N    1 ? 
ATOM   7546 C CA   . ILE A 1 466 ? -13.855 -45.586 -28.670 1.000 22.854 0 570  ILE A CA   1 ? 
ATOM   7547 C C    . ILE A 1 466 ? -12.469 -46.210 -28.564 1.000 20.882 0 570  ILE A C    1 ? 
ATOM   7548 O O    . ILE A 1 466 ? -12.122 -46.847 -27.567 1.000 20.849 0 570  ILE A O    1 ? 
ATOM   7549 C CB   . ILE A 1 466 ? -14.023 -44.265 -27.908 1.000 26.734 0 570  ILE A CB   1 ? 
ATOM   7550 C CG1  . ILE A 1 466 ? -15.323 -43.595 -28.434 1.000 26.384 0 570  ILE A CG1  1 ? 
ATOM   7551 C CG2  . ILE A 1 466 ? -12.778 -43.387 -28.073 1.000 28.579 0 570  ILE A CG2  1 ? 
ATOM   7552 C CD1  . ILE A 1 466 ? -15.648 -42.243 -27.846 1.000 30.841 0 570  ILE A CD1  1 ? 
ATOM   7553 H H    . ILE A 1 466 ? -15.275 -46.350 -27.392 1.000 23.608 0 570  ILE A H    1 c 
ATOM   7554 H HA   . ILE A 1 466 ? -14.045 -45.419 -29.614 1.000 22.994 0 570  ILE A HA   1 c 
ATOM   7555 H HB   . ILE A 1 466 ? -14.141 -44.466 -26.958 1.000 26.180 0 570  ILE A HB   1 c 
ATOM   7556 H HG12 . ILE A 1 466 ? -15.249 -43.498 -29.406 1.000 27.399 0 570  ILE A HG12 1 c 
ATOM   7557 H HG13 . ILE A 1 466 ? -16.075 -44.197 -28.256 1.000 27.401 0 570  ILE A HG13 1 c 
ATOM   7558 H HG21 . ILE A 1 466 ? -12.938 -42.514 -27.677 1.000 28.037 0 570  ILE A HG21 1 c 
ATOM   7559 H HG22 . ILE A 1 466 ? -12.577 -43.280 -29.018 1.000 28.020 0 570  ILE A HG22 1 c 
ATOM   7560 H HG23 . ILE A 1 466 ? -12.021 -43.805 -27.628 1.000 27.984 0 570  ILE A HG23 1 c 
ATOM   7561 H HD11 . ILE A 1 466 ? -15.650 -42.301 -26.872 1.000 29.359 0 570  ILE A HD11 1 c 
ATOM   7562 H HD12 . ILE A 1 466 ? -16.528 -41.955 -28.154 1.000 29.269 0 570  ILE A HD12 1 c 
ATOM   7563 H HD13 . ILE A 1 466 ? -14.979 -41.591 -28.130 1.000 29.174 0 570  ILE A HD13 1 c 
ATOM   7564 N N    . ASN A 1 467 ? -11.658 -45.965 -29.595 1.000 17.838 0 571  ASN A N    1 ? 
ATOM   7565 C CA   . ASN A 1 467 ? -10.279 -46.440 -29.598 1.000 16.729 0 571  ASN A CA   1 ? 
ATOM   7566 C C    . ASN A 1 467 ? -9.422  -45.500 -28.763 1.000 15.290 0 571  ASN A C    1 ? 
ATOM   7567 O O    . ASN A 1 467 ? -8.896  -44.497 -29.262 1.000 14.199 0 571  ASN A O    1 ? 
ATOM   7568 C CB   . ASN A 1 467 ? -9.779  -46.544 -31.036 1.000 14.831 0 571  ASN A CB   1 ? 
ATOM   7569 C CG   . ASN A 1 467 ? -8.390  -47.146 -31.183 1.000 12.427 0 571  ASN A CG   1 ? 
ATOM   7570 O OD1  . ASN A 1 467 ? -7.582  -47.133 -30.267 1.000 13.375 0 571  ASN A OD1  1 ? 
ATOM   7571 N ND2  . ASN A 1 467 ? -8.136  -47.603 -32.389 1.000 14.806 0 571  ASN A ND2  1 ? 
ATOM   7572 H H    . ASN A 1 467 ? -11.965 -45.491 -30.314 1.000 18.298 0 571  ASN A H    1 c 
ATOM   7573 H HA   . ASN A 1 467 ? -10.252 -47.341 -29.203 1.000 16.334 0 571  ASN A HA   1 c 
ATOM   7574 H HB2  . ASN A 1 467 ? -10.411 -47.090 -31.546 1.000 14.634 0 571  ASN A HB2  1 c 
ATOM   7575 H HB3  . ASN A 1 467 ? -9.775  -45.650 -31.432 1.000 14.634 0 571  ASN A HB3  1 c 
ATOM   7576 H HD21 . ASN A 1 467 ? -8.660  -47.383 -33.071 1.000 14.038 0 571  ASN A HD21 1 c 
ATOM   7577 H HD22 . ASN A 1 467 ? -7.435  -48.131 -32.521 1.000 14.026 0 571  ASN A HD22 1 c 
ATOM   7578 N N    . SER A 1 468 ? -9.222  -45.799 -27.487 1.000 15.418 0 572  SER A N    1 ? 
ATOM   7579 C CA   . SER A 1 468 ? -8.542  -44.956 -26.536 1.000 16.015 0 572  SER A CA   1 ? 
ATOM   7580 C C    . SER A 1 468 ? -7.096  -44.637 -26.946 1.000 15.056 0 572  SER A C    1 ? 
ATOM   7581 O O    . SER A 1 468 ? -6.603  -43.503 -26.868 1.000 16.004 0 572  SER A O    1 ? 
ATOM   7582 C CB   . SER A 1 468 ? -8.681  -45.611 -25.170 1.000 18.008 0 572  SER A CB   1 ? 
ATOM   7583 O OG   . SER A 1 468 ? -7.862  -44.963 -24.236 1.000 25.038 0 572  SER A OG   1 ? 
ATOM   7584 H H    . SER A 1 468 ? -9.541  -46.602 -27.189 1.000 15.580 0 572  SER A H    1 c 
ATOM   7585 H HA   . SER A 1 468 ? -9.033  -44.096 -26.504 1.000 16.064 0 572  SER A HA   1 c 
ATOM   7586 H HB2  . SER A 1 468 ? -9.611  -45.564 -24.879 1.000 18.924 0 572  SER A HB2  1 c 
ATOM   7587 H HB3  . SER A 1 468 ? -8.424  -46.550 -25.231 1.000 18.950 0 572  SER A HB3  1 c 
ATOM   7588 H HG   . SER A 1 468 ? -7.957  -45.343 -23.486 0.000 25.060 0 572  SER A HG   1 c 
ATOM   7589 N N    A SER A 1 469 ? -6.387  -45.663 -27.426 0.500 14.749 0 573  SER A N    1 ? 
ATOM   7590 N N    B SER A 1 469 ? -6.342  -45.658 -27.392 0.500 14.351 0 573  SER A N    1 ? 
ATOM   7591 C CA   A SER A 1 469 ? -4.999  -45.498 -27.785 0.500 14.072 0 573  SER A CA   1 ? 
ATOM   7592 C CA   B SER A 1 469 ? -4.958  -45.453 -27.769 0.500 13.600 0 573  SER A CA   1 ? 
ATOM   7593 C C    A SER A 1 469 ? -4.850  -44.544 -28.973 0.500 12.662 0 573  SER A C    1 ? 
ATOM   7594 C C    B SER A 1 469 ? -4.856  -44.507 -28.970 0.500 12.359 0 573  SER A C    1 ? 
ATOM   7595 O O    A SER A 1 469 ? -3.970  -43.707 -28.949 0.500 12.627 0 573  SER A O    1 ? 
ATOM   7596 O O    B SER A 1 469 ? -3.998  -43.649 -28.968 0.500 12.443 0 573  SER A O    1 ? 
ATOM   7597 C CB   A SER A 1 469 ? -4.379  -46.832 -28.089 0.500 13.745 0 573  SER A CB   1 ? 
ATOM   7598 C CB   B SER A 1 469 ? -4.253  -46.756 -28.095 0.500 12.898 0 573  SER A CB   1 ? 
ATOM   7599 O OG   A SER A 1 469 ? -4.417  -47.639 -26.917 0.500 15.867 0 573  SER A OG   1 ? 
ATOM   7600 O OG   B SER A 1 469 ? -2.895  -46.547 -28.458 0.500 14.957 0 573  SER A OG   1 ? 
ATOM   7601 H H    A SER A 1 469 ? -6.778  -46.483 -27.527 0.500 14.678 0 573  SER A H    1 c 
ATOM   7602 H H    B SER A 1 469 ? -6.701  -46.496 -27.456 0.500 14.358 0 573  SER A H    1 c 
ATOM   7603 H HA   A SER A 1 469 ? -4.525  -45.104 -27.009 0.500 13.942 0 573  SER A HA   1 c 
ATOM   7604 H HA   B SER A 1 469 ? -4.491  -45.031 -27.004 0.500 13.454 0 573  SER A HA   1 c 
ATOM   7605 H HB2  A SER A 1 469 ? -4.875  -47.269 -28.807 0.500 14.299 0 573  SER A HB2  1 c 
ATOM   7606 H HB2  B SER A 1 469 ? -4.293  -47.345 -27.318 0.500 13.522 0 573  SER A HB2  1 c 
ATOM   7607 H HB3  A SER A 1 469 ? -3.455  -46.708 -28.376 0.500 14.299 0 573  SER A HB3  1 c 
ATOM   7608 H HB3  B SER A 1 469 ? -4.719  -47.196 -28.831 0.500 13.522 0 573  SER A HB3  1 c 
ATOM   7609 H HG   A SER A 1 469 ? -4.067  -48.388 -27.092 0.000 15.890 0 573  SER A HG   1 c 
ATOM   7610 H HG   B SER A 1 469 ? -2.545  -47.298 -28.630 0.000 14.950 0 573  SER A HG   1 c 
ATOM   7611 N N    . ALA A 1 470 ? -5.717  -44.686 -29.969 1.000 11.478 0 574  ALA A N    1 ? 
ATOM   7612 C CA   . ALA A 1 470 ? -5.678  -43.829 -31.161 1.000 10.705 0 574  ALA A CA   1 ? 
ATOM   7613 C C    . ALA A 1 470 ? -6.041  -42.377 -30.782 1.000 11.974 0 574  ALA A C    1 ? 
ATOM   7614 O O    . ALA A 1 470 ? -5.457  -41.428 -31.304 1.000 11.539 0 574  ALA A O    1 ? 
ATOM   7615 C CB   . ALA A 1 470 ? -6.534  -44.380 -32.252 1.000 11.253 0 574  ALA A CB   1 ? 
ATOM   7616 H H    . ALA A 1 470 ? -6.347  -45.347 -29.919 1.000 11.764 0 574  ALA A H    1 c 
ATOM   7617 H HA   . ALA A 1 470 ? -4.737  -43.821 -31.489 1.000 11.203 0 574  ALA A HA   1 c 
ATOM   7618 H HB1  . ALA A 1 470 ? -6.219  -45.265 -32.500 1.000 11.086 0 574  ALA A HB1  1 c 
ATOM   7619 H HB2  . ALA A 1 470 ? -7.455  -44.441 -31.946 1.000 11.086 0 574  ALA A HB2  1 c 
ATOM   7620 H HB3  . ALA A 1 470 ? -6.492  -43.795 -33.027 1.000 11.086 0 574  ALA A HB3  1 c 
ATOM   7621 N N    . ILE A 1 471 ? -7.036  -42.169 -29.911 1.000 13.067 0 575  ILE A N    1 ? 
ATOM   7622 C CA   . ILE A 1 471 ? -7.385  -40.827 -29.425 1.000 13.282 0 575  ILE A CA   1 ? 
ATOM   7623 C C    . ILE A 1 471 ? -6.202  -40.170 -28.767 1.000 13.878 0 575  ILE A C    1 ? 
ATOM   7624 O O    . ILE A 1 471 ? -5.894  -38.972 -29.015 1.000 12.804 0 575  ILE A O    1 ? 
ATOM   7625 C CB   . ILE A 1 471 ? -8.557  -40.904 -28.427 1.000 14.748 0 575  ILE A CB   1 ? 
ATOM   7626 C CG1  . ILE A 1 471 ? -9.788  -41.357 -29.069 1.000 17.599 0 575  ILE A CG1  1 ? 
ATOM   7627 C CG2  . ILE A 1 471 ? -8.770  -39.530 -27.777 1.000 14.919 0 575  ILE A CG2  1 ? 
ATOM   7628 C CD1  . ILE A 1 471 ? -10.651 -40.296 -29.731 1.000 23.487 0 575  ILE A CD1  1 ? 
ATOM   7629 H H    . ILE A 1 471 ? -7.512  -42.885 -29.601 1.000 12.891 0 575  ILE A H    1 c 
ATOM   7630 H HA   . ILE A 1 471 ? -7.661  -40.283 -30.189 1.000 13.605 0 575  ILE A HA   1 c 
ATOM   7631 H HB   . ILE A 1 471 ? -8.323  -41.545 -27.727 1.000 15.009 0 575  ILE A HB   1 c 
ATOM   7632 H HG12 . ILE A 1 471 ? -9.555  -42.022 -29.748 1.000 17.896 0 575  ILE A HG12 1 c 
ATOM   7633 H HG13 . ILE A 1 471 ? -10.331 -41.812 -28.394 1.000 18.000 0 575  ILE A HG13 1 c 
ATOM   7634 H HG21 . ILE A 1 471 ? -9.629  -39.513 -27.321 1.000 14.968 0 575  ILE A HG21 1 c 
ATOM   7635 H HG22 . ILE A 1 471 ? -8.753  -38.838 -28.459 1.000 14.922 0 575  ILE A HG22 1 c 
ATOM   7636 H HG23 . ILE A 1 471 ? -8.065  -39.362 -27.130 1.000 14.892 0 575  ILE A HG23 1 c 
ATOM   7637 H HD11 . ILE A 1 471 ? -11.053 -39.713 -29.059 1.000 21.419 0 575  ILE A HD11 1 c 
ATOM   7638 H HD12 . ILE A 1 471 ? -11.359 -40.733 -30.242 1.000 21.488 0 575  ILE A HD12 1 c 
ATOM   7639 H HD13 . ILE A 1 471 ? -10.100 -39.765 -30.333 1.000 21.336 0 575  ILE A HD13 1 c 
ATOM   7640 N N    A LYS A 1 472 ? -5.488  -40.861 -27.859 0.500 13.616 0 576  LYS A N    1 ? 
ATOM   7641 N N    B LYS A 1 472 ? -5.570  -40.914 -27.876 0.500 13.979 0 576  LYS A N    1 ? 
ATOM   7642 C CA   A LYS A 1 472 ? -4.323  -40.318 -27.187 0.500 15.067 0 576  LYS A CA   1 ? 
ATOM   7643 C CA   B LYS A 1 472 ? -4.427  -40.425 -27.171 0.500 14.559 0 576  LYS A CA   1 ? 
ATOM   7644 C C    A LYS A 1 472 ? -3.238  -39.916 -28.180 0.500 13.499 0 576  LYS A C    1 ? 
ATOM   7645 C C    B LYS A 1 472 ? -3.385  -39.936 -28.177 0.500 13.084 0 576  LYS A C    1 ? 
ATOM   7646 O O    A LYS A 1 472 ? -2.514  -38.918 -28.014 0.500 13.542 0 576  LYS A O    1 ? 
ATOM   7647 O O    B LYS A 1 472 ? -2.952  -38.795 -28.064 0.500 13.363 0 576  LYS A O    1 ? 
ATOM   7648 C CB   A LYS A 1 472 ? -3.736  -41.299 -26.164 0.500 17.443 0 576  LYS A CB   1 ? 
ATOM   7649 C CB   B LYS A 1 472 ? -4.131  -41.494 -26.112 0.500 17.072 0 576  LYS A CB   1 ? 
ATOM   7650 C CG   A LYS A 1 472 ? -2.367  -40.973 -25.600 0.500 20.115 0 576  LYS A CG   1 ? 
ATOM   7651 C CG   B LYS A 1 472 ? -5.185  -41.671 -25.013 0.500 19.884 0 576  LYS A CG   1 ? 
ATOM   7652 C CD   A LYS A 1 472 ? -1.914  -42.068 -24.633 0.500 23.657 0 576  LYS A CD   1 ? 
ATOM   7653 C CD   B LYS A 1 472 ? -4.889  -42.850 -24.086 0.500 22.384 0 576  LYS A CD   1 ? 
ATOM   7654 C CE   A LYS A 1 472 ? -0.436  -42.280 -24.625 0.500 26.955 0 576  LYS A CE   1 ? 
ATOM   7655 C CE   B LYS A 1 472 ? -5.291  -42.608 -22.672 0.500 25.863 0 576  LYS A CE   1 ? 
ATOM   7656 N NZ   A LYS A 1 472 ? -0.057  -43.194 -23.541 0.500 27.914 0 576  LYS A NZ   1 ? 
ATOM   7657 N NZ   B LYS A 1 472 ? -5.110  -43.793 -21.824 0.500 27.745 0 576  LYS A NZ   1 ? 
ATOM   7658 H H    A LYS A 1 472 ? -5.750  -41.711 -27.652 0.500 13.985 0 576  LYS A H    1 c 
ATOM   7659 H H    B LYS A 1 472 ? -5.869  -41.759 -27.698 0.500 14.073 0 576  LYS A H    1 c 
ATOM   7660 H HA   A LYS A 1 472 ? -4.607  -39.505 -26.697 0.500 14.861 0 576  LYS A HA   1 c 
ATOM   7661 H HA   B LYS A 1 472 ? -4.722  -39.627 -26.661 0.500 14.578 0 576  LYS A HA   1 c 
ATOM   7662 H HB2  A LYS A 1 472 ? -4.364  -41.368 -25.413 0.500 17.437 0 576  LYS A HB2  1 c 
ATOM   7663 H HB2  B LYS A 1 472 ? -4.016  -42.355 -26.567 0.500 17.047 0 576  LYS A HB2  1 c 
ATOM   7664 H HB3  A LYS A 1 472 ? -3.688  -42.184 -26.584 0.500 17.437 0 576  LYS A HB3  1 c 
ATOM   7665 H HB3  B LYS A 1 472 ? -3.277  -41.272 -25.683 0.500 17.047 0 576  LYS A HB3  1 c 
ATOM   7666 H HG2  A LYS A 1 472 ? -1.724  -40.899 -26.339 0.500 20.194 0 576  LYS A HG2  1 c 
ATOM   7667 H HG2  B LYS A 1 472 ? -5.223  -40.851 -24.481 0.500 19.625 0 576  LYS A HG2  1 c 
ATOM   7668 H HG3  A LYS A 1 472 ? -2.408  -40.112 -25.131 0.500 20.192 0 576  LYS A HG3  1 c 
ATOM   7669 H HG3  B LYS A 1 472 ? -6.062  -41.798 -25.432 0.500 19.681 0 576  LYS A HG3  1 c 
ATOM   7670 H HD2  A LYS A 1 472 ? -2.210  -41.837 -23.727 0.500 23.477 0 576  LYS A HD2  1 c 
ATOM   7671 H HD2  B LYS A 1 472 ? -5.365  -43.641 -24.420 0.500 22.617 0 576  LYS A HD2  1 c 
ATOM   7672 H HD3  A LYS A 1 472 ? -2.354  -42.910 -24.882 0.500 23.527 0 576  LYS A HD3  1 c 
ATOM   7673 H HD3  B LYS A 1 472 ? -3.927  -43.044 -24.115 0.500 22.556 0 576  LYS A HD3  1 c 
ATOM   7674 H HE2  A LYS A 1 472 ? -0.153  -42.659 -25.477 0.500 26.385 0 576  LYS A HE2  1 c 
ATOM   7675 H HE2  B LYS A 1 472 ? -4.757  -41.879 -22.309 0.500 25.441 0 576  LYS A HE2  1 c 
ATOM   7676 H HE3  A LYS A 1 472 ? 0.019   -41.429 -24.501 0.500 26.417 0 576  LYS A HE3  1 c 
ATOM   7677 H HE3  B LYS A 1 472 ? -6.225  -42.336 -22.646 0.500 25.477 0 576  LYS A HE3  1 c 
ATOM   7678 H HZ1  A LYS A 1 472 ? -0.467  -43.994 -23.656 0.500 27.615 0 576  LYS A HZ1  1 c 
ATOM   7679 H HZ1  B LYS A 1 472 ? -4.234  -44.026 -21.806 0.500 27.151 0 576  LYS A HZ1  1 c 
ATOM   7680 H HZ2  A LYS A 1 472 ? -0.306  -42.844 -22.743 0.500 27.615 0 576  LYS A HZ2  1 c 
ATOM   7681 H HZ2  B LYS A 1 472 ? -5.594  -44.484 -22.156 0.500 27.151 0 576  LYS A HZ2  1 c 
ATOM   7682 H HZ3  A LYS A 1 472 ? 0.841   -43.317 -23.544 0.500 27.615 0 576  LYS A HZ3  1 c 
ATOM   7683 H HZ3  B LYS A 1 472 ? -5.388  -43.612 -20.981 0.500 27.151 0 576  LYS A HZ3  1 c 
ATOM   7684 N N    . LEU A 1 473 ? -3.045  -40.767 -29.180 1.000 11.884 0 577  LEU A N    1 ? 
ATOM   7685 C CA   . LEU A 1 473 ? -2.039  -40.437 -30.190 1.000 11.668 0 577  LEU A CA   1 ? 
ATOM   7686 C C    . LEU A 1 473 ? -2.430  -39.144 -30.927 1.000 10.381 0 577  LEU A C    1 ? 
ATOM   7687 O O    . LEU A 1 473 ? -1.571  -38.314 -31.194 1.000 11.862 0 577  LEU A O    1 ? 
ATOM   7688 C CB   . LEU A 1 473 ? -1.861  -41.584 -31.189 1.000 12.443 0 577  LEU A CB   1 ? 
ATOM   7689 C CG   . LEU A 1 473 ? -1.119  -42.819 -30.661 1.000 13.152 0 577  LEU A CG   1 ? 
ATOM   7690 C CD1  . LEU A 1 473 ? -1.240  -43.943 -31.662 1.000 13.596 0 577  LEU A CD1  1 ? 
ATOM   7691 C CD2  . LEU A 1 473 ? 0.356   -42.549 -30.312 1.000 17.323 0 577  LEU A CD2  1 ? 
ATOM   7692 H H    . LEU A 1 473 ? -3.488  -41.565 -29.235 1.000 12.406 0 577  LEU A H    1 c 
ATOM   7693 H HA   . LEU A 1 473 ? -1.178  -40.280 -29.726 1.000 11.663 0 577  LEU A HA   1 c 
ATOM   7694 H HB2  . LEU A 1 473 ? -2.753  -41.865 -31.496 1.000 12.427 0 577  LEU A HB2  1 c 
ATOM   7695 H HB3  . LEU A 1 473 ? -1.370  -41.238 -31.970 1.000 12.407 0 577  LEU A HB3  1 c 
ATOM   7696 H HG   . LEU A 1 473 ? -1.571  -43.111 -29.829 1.000 13.774 0 577  LEU A HG   1 c 
ATOM   7697 H HD11 . LEU A 1 473 ? -2.178  -44.166 -31.790 1.000 13.456 0 577  LEU A HD11 1 c 
ATOM   7698 H HD12 . LEU A 1 473 ? -0.764  -44.724 -31.333 1.000 13.461 0 577  LEU A HD12 1 c 
ATOM   7699 H HD13 . LEU A 1 473 ? -0.856  -43.665 -32.511 1.000 13.461 0 577  LEU A HD13 1 c 
ATOM   7700 H HD21 . LEU A 1 473 ? 0.407   -41.920 -29.573 1.000 15.943 0 577  LEU A HD21 1 c 
ATOM   7701 H HD22 . LEU A 1 473 ? 0.811   -42.176 -31.086 1.000 15.972 0 577  LEU A HD22 1 c 
ATOM   7702 H HD23 . LEU A 1 473 ? 0.787   -43.382 -30.055 1.000 15.972 0 577  LEU A HD23 1 c 
ATOM   7703 N N    . GLN A 1 474 ? -3.699  -39.007 -31.255 1.000 9.565  0 578  GLN A N    1 ? 
ATOM   7704 C CA   . GLN A 1 474 ? -4.140  -37.865 -32.036 1.000 9.659  0 578  GLN A CA   1 ? 
ATOM   7705 C C    . GLN A 1 474 ? -4.154  -36.587 -31.197 1.000 9.879  0 578  GLN A C    1 ? 
ATOM   7706 O O    . GLN A 1 474 ? -3.872  -35.502 -31.703 1.000 10.272 0 578  GLN A O    1 ? 
ATOM   7707 C CB   . GLN A 1 474 ? -5.500  -38.137 -32.633 1.000 9.766  0 578  GLN A CB   1 ? 
ATOM   7708 C CG   . GLN A 1 474 ? -6.024  -37.068 -33.586 1.000 9.851  0 578  GLN A CG   1 ? 
ATOM   7709 C CD   . GLN A 1 474 ? -5.105  -36.720 -34.739 1.000 10.195 0 578  GLN A CD   1 ? 
ATOM   7710 O OE1  . GLN A 1 474 ? -4.235  -37.510 -35.124 1.000 10.885 0 578  GLN A OE1  1 ? 
ATOM   7711 N NE2  . GLN A 1 474 ? -5.343  -35.564 -35.355 1.000 9.894  0 578  GLN A NE2  1 ? 
ATOM   7712 H H    . GLN A 1 474 ? -4.312  -39.634 -30.996 1.000 9.800  0 578  GLN A H    1 c 
ATOM   7713 H HA   . GLN A 1 474 ? -3.496  -37.739 -32.777 1.000 9.723  0 578  GLN A HA   1 c 
ATOM   7714 H HB2  . GLN A 1 474 ? -5.462  -38.990 -33.110 1.000 9.768  0 578  GLN A HB2  1 c 
ATOM   7715 H HB3  . GLN A 1 474 ? -6.139  -38.241 -31.899 1.000 9.798  0 578  GLN A HB3  1 c 
ATOM   7716 H HG2  . GLN A 1 474 ? -6.879  -37.370 -33.960 1.000 9.910  0 578  GLN A HG2  1 c 
ATOM   7717 H HG3  . GLN A 1 474 ? -6.202  -36.248 -33.078 1.000 9.910  0 578  GLN A HG3  1 c 
ATOM   7718 H HE21 . GLN A 1 474 ? -6.097  -35.125 -35.199 1.000 9.970  0 578  GLN A HE21 1 c 
ATOM   7719 H HE22 . GLN A 1 474 ? -4.746  -35.236 -35.922 1.000 9.988  0 578  GLN A HE22 1 c 
ATOM   7720 N N    . LEU A 1 475 ? -4.464  -36.673 -29.908 1.000 11.385 0 579  LEU A N    1 ? 
ATOM   7721 C CA   . LEU A 1 475 ? -4.564  -35.463 -29.091 1.000 10.998 0 579  LEU A CA   1 ? 
ATOM   7722 C C    . LEU A 1 475 ? -3.188  -34.933 -28.719 1.000 11.439 0 579  LEU A C    1 ? 
ATOM   7723 O O    . LEU A 1 475 ? -2.998  -33.722 -28.493 1.000 10.427 0 579  LEU A O    1 ? 
ATOM   7724 C CB   . LEU A 1 475 ? -5.396  -35.759 -27.830 1.000 12.373 0 579  LEU A CB   1 ? 
ATOM   7725 C CG   . LEU A 1 475 ? -5.719  -34.530 -26.972 1.000 12.512 0 579  LEU A CG   1 ? 
ATOM   7726 C CD1  . LEU A 1 475 ? -6.732  -33.676 -27.616 1.000 15.040 0 579  LEU A CD1  1 ? 
ATOM   7727 C CD2  . LEU A 1 475 ? -6.178  -34.902 -25.554 1.000 14.426 0 579  LEU A CD2  1 ? 
ATOM   7728 H H    . LEU A 1 475 ? -4.622  -37.487 -29.523 1.000 10.911 0 579  LEU A H    1 c 
ATOM   7729 H HA   . LEU A 1 475 ? -5.029  -34.770 -29.625 1.000 11.408 0 579  LEU A HA   1 c 
ATOM   7730 H HB2  . LEU A 1 475 ? -6.242  -36.179 -28.107 1.000 12.154 0 579  LEU A HB2  1 c 
ATOM   7731 H HB3  . LEU A 1 475 ? -4.899  -36.405 -27.276 1.000 12.093 0 579  LEU A HB3  1 c 
ATOM   7732 H HG   . LEU A 1 475 ? -4.891  -33.994 -26.881 1.000 13.256 0 579  LEU A HG   1 c 
ATOM   7733 H HD11 . LEU A 1 475 ? -6.383  -33.333 -28.456 1.000 14.172 0 579  LEU A HD11 1 c 
ATOM   7734 H HD12 . LEU A 1 475 ? -6.949  -32.931 -27.031 1.000 14.202 0 579  LEU A HD12 1 c 
ATOM   7735 H HD13 . LEU A 1 475 ? -7.535  -34.196 -27.788 1.000 14.173 0 579  LEU A HD13 1 c 
ATOM   7736 H HD21 . LEU A 1 475 ? -5.480  -35.412 -25.110 1.000 13.838 0 579  LEU A HD21 1 c 
ATOM   7737 H HD22 . LEU A 1 475 ? -6.987  -35.437 -25.605 1.000 13.838 0 579  LEU A HD22 1 c 
ATOM   7738 H HD23 . LEU A 1 475 ? -6.358  -34.092 -25.048 1.000 13.840 0 579  LEU A HD23 1 c 
ATOM   7739 N N    . THR A 1 476 ? -2.162  -35.785 -28.627 1.000 12.358 0 580  THR A N    1 ? 
ATOM   7740 C CA   . THR A 1 476 ? -0.864  -35.383 -28.101 1.000 14.195 0 580  THR A CA   1 ? 
ATOM   7741 C C    . THR A 1 476 ? 0.186   -35.295 -29.192 1.000 17.148 0 580  THR A C    1 ? 
ATOM   7742 O O    . THR A 1 476 ? 1.328   -34.904 -28.926 1.000 21.170 0 580  THR A O    1 ? 
ATOM   7743 C CB   . THR A 1 476 ? -0.446  -36.353 -26.997 1.000 15.705 0 580  THR A CB   1 ? 
ATOM   7744 O OG1  . THR A 1 476 ? -0.251  -37.630 -27.597 1.000 16.713 0 580  THR A OG1  1 ? 
ATOM   7745 C CG2  . THR A 1 476 ? -1.481  -36.387 -25.896 1.000 15.729 0 580  THR A CG2  1 ? 
ATOM   7746 H H    . THR A 1 476 ? -2.286  -36.658 -28.868 1.000 12.581 0 580  THR A H    1 c 
ATOM   7747 H HA   . THR A 1 476 ? -0.960  -34.493 -27.699 1.000 14.528 0 580  THR A HA   1 c 
ATOM   7748 H HB   . THR A 1 476 ? 0.409   -36.048 -26.610 1.000 15.611 0 580  THR A HB   1 c 
ATOM   7749 H HG1  . THR A 1 476 ? -0.986  -37.892 -27.965 0.000 16.710 0 580  THR A HG1  1 c 
ATOM   7750 H HG21 . THR A 1 476 ? -1.155  -36.935 -25.163 1.000 15.708 0 580  THR A HG21 1 c 
ATOM   7751 H HG22 . THR A 1 476 ? -2.309  -36.764 -26.238 1.000 15.698 0 580  THR A HG22 1 c 
ATOM   7752 H HG23 . THR A 1 476 ? -1.645  -35.483 -25.576 1.000 15.714 0 580  THR A HG23 1 c 
ATOM   7753 N N    . ALA A 1 477 ? -0.220  -35.838 -30.354 1.000 18.370 0 581  ALA A N    1 ? 
ATOM   7754 C CA   . ALA A 1 477 ? 0.435   -35.866 -31.640 1.000 20.664 0 581  ALA A CA   1 ? 
ATOM   7755 C C    . ALA A 1 477 ? 1.738   -36.640 -31.368 1.000 26.556 0 581  ALA A C    1 ? 
ATOM   7756 O O    . ALA A 1 477 ? 2.775   -36.446 -32.001 1.000 34.438 0 581  ALA A O    1 ? 
ATOM   7757 C CB   . ALA A 1 477 ? 0.391   -34.430 -32.280 1.000 17.780 0 581  ALA A CB   1 ? 
ATOM   7758 H H    . ALA A 1 477 ? -1.032  -36.255 -30.325 1.000 18.449 0 581  ALA A H    1 c 
ATOM   7759 H HA   . ALA A 1 477 ? -0.117  -36.452 -32.225 1.000 20.584 0 581  ALA A HA   1 c 
ATOM   7760 H HB1  . ALA A 1 477 ? -0.504  -34.064 -32.199 1.000 18.393 0 581  ALA A HB1  1 c 
ATOM   7761 H HB2  . ALA A 1 477 ? 1.020   -33.848 -31.822 1.000 18.520 0 581  ALA A HB2  1 c 
ATOM   7762 H HB3  . ALA A 1 477 ? 0.630   -34.486 -33.220 1.000 18.520 0 581  ALA A HB3  1 c 
ATOM   7763 N N    . GLN A 1 478 ? 1.583   -37.606 -30.425 1.000 26.773 0 582  GLN A N    1 ? 
ATOM   7764 C CA   . GLN A 1 478 ? 2.593   -38.579 -29.998 1.000 30.853 0 582  GLN A CA   1 ? 
ATOM   7765 C C    . GLN A 1 478 ? 2.864   -39.448 -31.202 1.000 29.898 0 582  GLN A C    1 ? 
ATOM   7766 O O    . GLN A 1 478 ? 1.956   -39.812 -31.969 1.000 35.411 0 582  GLN A O    1 ? 
ATOM   7767 C CB   . GLN A 1 478 ? 2.171   -39.347 -28.726 1.000 34.980 0 582  GLN A CB   1 ? 
ATOM   7768 C CG   . GLN A 1 478 ? 3.069   -40.502 -28.270 1.000 35.364 0 582  GLN A CG   1 ? 
ATOM   7769 C CD   . GLN A 1 478 ? 2.462   -41.338 -27.154 1.000 38.749 0 582  GLN A CD   1 ? 
ATOM   7770 O OE1  . GLN A 1 478 ? 1.931   -40.811 -26.168 1.000 48.381 0 582  GLN A OE1  1 ? 
ATOM   7771 N NE2  . GLN A 1 478 ? 2.521   -42.660 -27.274 1.000 38.140 0 582  GLN A NE2  1 ? 
ATOM   7772 H H    . GLN A 1 478 ? 0.760   -37.678 -30.036 1.000 27.348 0 582  GLN A H    1 c 
ATOM   7773 H HA   . GLN A 1 478 ? 3.421   -38.079 -29.785 1.000 30.461 0 582  GLN A HA   1 c 
ATOM   7774 H HB2  . GLN A 1 478 ? 2.111   -38.700 -27.993 1.000 33.930 0 582  GLN A HB2  1 c 
ATOM   7775 H HB3  . GLN A 1 478 ? 1.269   -39.700 -28.874 1.000 34.005 0 582  GLN A HB3  1 c 
ATOM   7776 H HG2  . GLN A 1 478 ? 3.255   -41.088 -29.035 1.000 36.020 0 582  GLN A HG2  1 c 
ATOM   7777 H HG3  . GLN A 1 478 ? 3.926   -40.140 -27.959 1.000 36.024 0 582  GLN A HG3  1 c 
ATOM   7778 H HE21 . GLN A 1 478 ? 2.991   -43.029 -27.930 1.000 38.300 0 582  GLN A HE21 1 c 
ATOM   7779 H HE22 . GLN A 1 478 ? 2.089   -43.175 -26.695 1.000 38.386 0 582  GLN A HE22 1 c 
ATOM   7780 N N    . SER A 1 479 ? 4.138   -39.731 -31.418 1.000 24.803 0 583  SER A N    1 ? 
ATOM   7781 C CA   . SER A 1 479 ? 4.528   -40.286 -32.718 1.000 28.069 0 583  SER A CA   1 ? 
ATOM   7782 C C    . SER A 1 479 ? 4.409   -41.826 -32.665 1.000 24.402 0 583  SER A C    1 ? 
ATOM   7783 O O    . SER A 1 479 ? 3.944   -42.470 -33.622 1.000 22.324 0 583  SER A O    1 ? 
ATOM   7784 C CB   . SER A 1 479 ? 5.921   -39.854 -33.104 1.000 24.587 0 583  SER A CB   1 ? 
ATOM   7785 O OG   . SER A 1 479 ? 6.180   -38.445 -33.028 1.000 39.373 0 583  SER A OG   1 ? 
ATOM   7786 H H    . SER A 1 479 ? 4.772   -39.586 -30.776 1.000 26.657 0 583  SER A H    1 c 
ATOM   7787 H HA   . SER A 1 479 ? 3.897   -39.950 -33.405 1.000 26.141 0 583  SER A HA   1 c 
ATOM   7788 H HB2  . SER A 1 479 ? 6.557   -40.316 -32.527 1.000 28.316 0 583  SER A HB2  1 c 
ATOM   7789 H HB3  . SER A 1 479 ? 6.097   -40.150 -34.009 1.000 28.360 0 583  SER A HB3  1 c 
ATOM   7790 H HG   . SER A 1 479 ? 6.980   -38.303 -33.263 0.000 39.460 0 583  SER A HG   1 c 
ATOM   7791 N N    . GLN A 1 480 ? 4.764   -42.405 -31.505 1.000 18.886 0 584  GLN A N    1 ? 
ATOM   7792 C CA   . GLN A 1 480 ? 5.097   -43.826 -31.399 1.000 19.220 0 584  GLN A CA   1 ? 
ATOM   7793 C C    . GLN A 1 480 ? 4.370   -44.481 -30.237 1.000 20.543 0 584  GLN A C    1 ? 
ATOM   7794 O O    . GLN A 1 480 ? 4.017   -43.817 -29.259 1.000 21.164 0 584  GLN A O    1 ? 
ATOM   7795 C CB   . GLN A 1 480 ? 6.602   -43.965 -31.220 1.000 18.230 0 584  GLN A CB   1 ? 
ATOM   7796 C CG   . GLN A 1 480 ? 7.376   -43.664 -32.492 1.000 19.823 0 584  GLN A CG   1 ? 
ATOM   7797 C CD   . GLN A 1 480 ? 8.787   -43.198 -32.267 1.000 22.470 0 584  GLN A CD   1 ? 
ATOM   7798 O OE1  . GLN A 1 480 ? 9.784   -43.742 -32.776 1.000 20.929 0 584  GLN A OE1  1 ? 
ATOM   7799 N NE2  . GLN A 1 480 ? 8.865   -42.102 -31.536 1.000 24.555 0 584  GLN A NE2  1 ? 
ATOM   7800 H H    . GLN A 1 480 ? 4.801   -41.896 -30.747 1.000 20.282 0 584  GLN A H    1 c 
ATOM   7801 H HA   . GLN A 1 480 ? 4.827   -44.276 -32.236 1.000 19.243 0 584  GLN A HA   1 c 
ATOM   7802 H HB2  . GLN A 1 480 ? 6.894   -43.355 -30.511 1.000 18.884 0 584  GLN A HB2  1 c 
ATOM   7803 H HB3  . GLN A 1 480 ? 6.805   -44.880 -30.931 1.000 18.831 0 584  GLN A HB3  1 c 
ATOM   7804 H HG2  . GLN A 1 480 ? 7.404   -44.472 -33.047 1.000 20.025 0 584  GLN A HG2  1 c 
ATOM   7805 H HG3  . GLN A 1 480 ? 6.902   -42.974 -33.002 1.000 20.033 0 584  GLN A HG3  1 c 
ATOM   7806 H HE21 . GLN A 1 480 ? 8.163   -41.565 -31.458 1.000 23.816 0 584  GLN A HE21 1 c 
ATOM   7807 H HE22 . GLN A 1 480 ? 9.623   -41.902 -31.121 1.000 23.875 0 584  GLN A HE22 1 c 
ATOM   7808 N N    . VAL A 1 481 ? 4.182   -45.799 -30.330 1.000 17.833 0 585  VAL A N    1 ? 
ATOM   7809 C CA   . VAL A 1 481 ? 3.700   -46.639 -29.234 1.000 18.526 0 585  VAL A CA   1 ? 
ATOM   7810 C C    . VAL A 1 481 ? 4.919   -47.330 -28.605 1.000 19.728 0 585  VAL A C    1 ? 
ATOM   7811 O O    . VAL A 1 481 ? 6.028   -47.169 -29.088 1.000 22.799 0 585  VAL A O    1 ? 
ATOM   7812 C CB   . VAL A 1 481 ? 2.596   -47.645 -29.621 1.000 21.930 0 585  VAL A CB   1 ? 
ATOM   7813 C CG1  . VAL A 1 481 ? 1.255   -46.969 -29.907 1.000 25.806 0 585  VAL A CG1  1 ? 
ATOM   7814 C CG2  . VAL A 1 481 ? 2.963   -48.545 -30.787 1.000 23.365 0 585  VAL A CG2  1 ? 
ATOM   7815 H H    . VAL A 1 481 ? 4.374   -46.203 -31.127 1.000 18.670 0 585  VAL A H    1 c 
ATOM   7816 H HA   . VAL A 1 481 ? 3.322   -46.046 -28.557 1.000 19.211 0 585  VAL A HA   1 c 
ATOM   7817 H HB   . VAL A 1 481 ? 2.457   -48.230 -28.841 1.000 22.124 0 585  VAL A HB   1 c 
ATOM   7818 H HG11 . VAL A 1 481 ? 1.351   -46.361 -30.659 1.000 24.597 0 585  VAL A HG11 1 c 
ATOM   7819 H HG12 . VAL A 1 481 ? 0.969   -46.470 -29.124 1.000 24.597 0 585  VAL A HG12 1 c 
ATOM   7820 H HG13 . VAL A 1 481 ? 0.590   -47.644 -30.120 1.000 24.588 0 585  VAL A HG13 1 c 
ATOM   7821 H HG21 . VAL A 1 481 ? 2.234   -49.163 -30.961 1.000 22.922 0 585  VAL A HG21 1 c 
ATOM   7822 H HG22 . VAL A 1 481 ? 3.767   -49.048 -30.570 1.000 22.902 0 585  VAL A HG22 1 c 
ATOM   7823 H HG23 . VAL A 1 481 ? 3.123   -48.005 -31.578 1.000 22.864 0 585  VAL A HG23 1 c 
ATOM   7824 N N    . GLN A 1 482 ? 4.726   -48.059 -27.492 1.000 18.599 0 586  GLN A N    1 ? 
ATOM   7825 C CA   . GLN A 1 482 ? 5.843   -48.677 -26.775 1.000 21.831 0 586  GLN A CA   1 ? 
ATOM   7826 C C    . GLN A 1 482 ? 6.490   -49.764 -27.646 1.000 20.934 0 586  GLN A C    1 ? 
ATOM   7827 O O    . GLN A 1 482 ? 5.834   -50.464 -28.403 1.000 19.803 0 586  GLN A O    1 ? 
ATOM   7828 C CB   . GLN A 1 482 ? 5.409   -49.290 -25.439 1.000 22.968 0 586  GLN A CB   1 ? 
ATOM   7829 H H    . GLN A 1 482 ? 3.879   -48.167 -27.165 1.000 19.599 0 586  GLN A H    1 c 
ATOM   7830 H HA   . GLN A 1 482 ? 6.518   -47.975 -26.592 1.000 21.197 0 586  GLN A HA   1 c 
ATOM   7831 H HB2  . GLN A 1 482 ? 4.755   -49.998 -25.617 1.000 22.627 0 586  GLN A HB2  1 c 
ATOM   7832 H HB3  . GLN A 1 482 ? 6.190   -49.711 -25.019 0.000 22.970 0 586  GLN A HB3  1 c 
ATOM   7833 N N    . MET A 1 483 ? 7.825   -49.834 -27.590 1.000 20.440 0 587  MET A N    1 ? 
ATOM   7834 C CA   . MET A 1 483 ? 8.604   -50.755 -28.405 1.000 22.889 0 587  MET A CA   1 ? 
ATOM   7835 C C    . MET A 1 483 ? 8.211   -52.209 -28.136 1.000 23.224 0 587  MET A C    1 ? 
ATOM   7836 O O    . MET A 1 483 ? 7.901   -52.974 -29.046 1.000 20.762 0 587  MET A O    1 ? 
ATOM   7837 C CB   . MET A 1 483 ? 10.095  -50.592 -28.089 1.000 23.621 0 587  MET A CB   1 ? 
ATOM   7838 C CG   . MET A 1 483 ? 10.668  -49.233 -28.438 1.000 30.535 0 587  MET A CG   1 ? 
ATOM   7839 H H    . MET A 1 483 ? 8.269   -49.284 -27.010 1.000 21.155 0 587  MET A H    1 c 
ATOM   7840 H HA   . MET A 1 483 ? 8.440   -50.547 -29.359 1.000 22.574 0 587  MET A HA   1 c 
ATOM   7841 H HB2  . MET A 1 483 ? 10.228  -50.753 -27.130 1.000 24.881 0 587  MET A HB2  1 c 
ATOM   7842 H HB3  . MET A 1 483 ? 10.592  -51.280 -28.576 1.000 24.873 0 587  MET A HB3  1 c 
ATOM   7843 H HG2  . MET A 1 483 ? 10.665  -49.122 -29.410 1.000 28.293 0 587  MET A HG2  1 c 
ATOM   7844 H HG3  . MET A 1 483 ? 10.174  -48.539 -27.966 0.000 30.490 0 587  MET A HG3  1 c 
ATOM   7845 N N    . LYS A 1 484 ? 8.166   -52.593 -26.860 1.000 26.632 0 588  LYS A N    1 ? 
ATOM   7846 C CA   . LYS A 1 484 ? 7.940   -53.987 -26.495 1.000 27.157 0 588  LYS A CA   1 ? 
ATOM   7847 C C    . LYS A 1 484 ? 6.430   -54.221 -26.310 1.000 28.993 0 588  LYS A C    1 ? 
ATOM   7848 O O    . LYS A 1 484 ? 6.015   -55.409 -26.608 1.000 30.521 0 588  LYS A O    1 ? 
ATOM   7849 C CB   . LYS A 1 484 ? 8.827   -54.330 -25.285 1.000 34.615 0 588  LYS A CB   1 ? 
ATOM   7850 C CG   . LYS A 1 484 ? 10.295  -54.583 -25.668 1.000 44.054 0 588  LYS A CG   1 ? 
ATOM   7851 C CD   . LYS A 1 484 ? 11.293  -54.870 -24.548 1.000 51.868 0 588  LYS A CD   1 ? 
ATOM   7852 C CE   . LYS A 1 484 ? 12.676  -55.023 -25.136 1.000 58.912 0 588  LYS A CE   1 ? 
ATOM   7853 N NZ   . LYS A 1 484 ? 13.767  -54.986 -24.152 1.000 62.087 0 588  LYS A NZ   1 ? 
ATOM   7854 H H    . LYS A 1 484 ? 8.278   -51.974 -26.197 1.000 25.937 0 588  LYS A H    1 c 
ATOM   7855 H HA   . LYS A 1 484 ? 8.245   -54.555 -27.248 1.000 28.611 0 588  LYS A HA   1 c 
ATOM   7856 H HB2  . LYS A 1 484 ? 8.792   -53.594 -24.638 1.000 34.538 0 588  LYS A HB2  1 c 
ATOM   7857 H HB3  . LYS A 1 484 ? 8.474   -55.133 -24.847 1.000 34.597 0 588  LYS A HB3  1 c 
ATOM   7858 H HG2  . LYS A 1 484 ? 10.313  -55.337 -26.295 1.000 43.293 0 588  LYS A HG2  1 c 
ATOM   7859 H HG3  . LYS A 1 484 ? 10.611  -53.797 -26.165 1.000 43.363 0 588  LYS A HG3  1 c 
ATOM   7860 H HD2  . LYS A 1 484 ? 11.291  -54.129 -23.904 1.000 51.473 0 588  LYS A HD2  1 c 
ATOM   7861 H HD3  . LYS A 1 484 ? 11.041  -55.697 -24.084 1.000 51.473 0 588  LYS A HD3  1 c 
ATOM   7862 H HE2  . LYS A 1 484 ? 12.723  -55.870 -25.613 1.000 57.906 0 588  LYS A HE2  1 c 
ATOM   7863 H HE3  . LYS A 1 484 ? 12.826  -54.313 -25.785 1.000 57.743 0 588  LYS A HE3  1 c 
ATOM   7864 H HZ1  . LYS A 1 484 ? 13.668  -55.664 -23.560 1.000 61.092 0 588  LYS A HZ1  1 c 
ATOM   7865 H HZ2  . LYS A 1 484 ? 13.750  -54.197 -23.707 1.000 61.092 0 588  LYS A HZ2  1 c 
ATOM   7866 H HZ3  . LYS A 1 484 ? 14.563  -55.073 -24.574 1.000 61.092 0 588  LYS A HZ3  1 c 
HETATM 7867 C C1   . K5O B 2 .   ? -15.470 -8.781  -10.797 1.000 7.720  0 601  K5O A C1   1 ? 
HETATM 7868 N N1   . K5O B 2 .   ? -14.441 -7.959  -11.419 1.000 7.192  0 601  K5O A N1   1 ? 
HETATM 7869 C C2   . K5O B 2 .   ? -13.199 -8.368  -11.733 1.000 7.170  0 601  K5O A C2   1 ? 
HETATM 7870 N N2   . K5O B 2 .   ? -12.953 -9.681  -11.520 1.000 7.867  0 601  K5O A N2   1 ? 
HETATM 7871 C C3   . K5O B 2 .   ? -11.739 -10.137 -11.838 1.000 8.154  0 601  K5O A C3   1 ? 
HETATM 7872 N N3   . K5O B 2 .   ? -11.487 -11.454 -11.673 1.000 9.808  0 601  K5O A N3   1 ? 
HETATM 7873 C C4   . K5O B 2 .   ? -12.456 -12.457 -11.231 1.000 10.020 0 601  K5O A C4   1 ? 
HETATM 7874 C C5   . K5O B 2 .   ? -12.037 -13.063 -9.933  1.000 10.109 0 601  K5O A C5   1 ? 
HETATM 7875 C C6   . K5O B 2 .   ? -13.019 -14.156 -9.510  1.000 10.778 0 601  K5O A C6   1 ? 
HETATM 7876 N N4   . K5O B 2 .   ? -13.089 -15.211 -10.537 1.000 9.271  0 601  K5O A N4   1 ? 
HETATM 7877 C C7   . K5O B 2 .   ? -13.968 -16.295 -10.028 1.000 10.038 0 601  K5O A C7   1 ? 
HETATM 7878 C C8   . K5O B 2 .   ? -14.099 -17.538 -10.897 1.000 10.004 0 601  K5O A C8   1 ? 
HETATM 7879 C C9   . K5O B 2 .   ? -13.026 -18.406 -10.985 1.000 10.356 0 601  K5O A C9   1 ? 
HETATM 7880 C C10  . K5O B 2 .   ? -13.044 -19.570 -11.735 1.000 10.165 0 601  K5O A C10  1 ? 
HETATM 7881 C C11  . K5O B 2 .   ? -14.221 -19.857 -12.415 1.000 9.707  0 601  K5O A C11  1 ? 
HETATM 7882 N N5   . K5O B 2 .   ? -14.555 -20.919 -13.242 1.000 10.304 0 601  K5O A N5   1 ? 
HETATM 7883 C C12  . K5O B 2 .   ? -13.753 -22.141 -13.461 1.000 9.918  0 601  K5O A C12  1 ? 
HETATM 7884 C C13  . K5O B 2 .   ? -13.548 -23.009 -12.204 1.000 11.118 0 601  K5O A C13  1 ? 
HETATM 7885 C C14  . K5O B 2 .   ? -12.744 -24.240 -12.595 1.000 12.155 0 601  K5O A C14  1 ? 
HETATM 7886 N N6   . K5O B 2 .   ? -14.755 -23.463 -11.495 1.000 13.755 0 601  K5O A N6   1 ? 
HETATM 7887 C C15  . K5O B 2 .   ? -15.755 -24.263 -12.229 1.000 14.172 0 601  K5O A C15  1 ? 
HETATM 7888 C C16  . K5O B 2 .   ? -16.822 -24.820 -11.327 1.000 16.557 0 601  K5O A C16  1 ? 
HETATM 7889 N N7   . K5O B 2 .   ? -17.383 -23.757 -10.489 1.000 16.001 0 601  K5O A N7   1 ? 
HETATM 7890 C C17  . K5O B 2 .   ? -16.375 -23.117 -9.637  1.000 17.180 0 601  K5O A C17  1 ? 
HETATM 7891 C C18  . K5O B 2 .   ? -15.346 -22.494 -10.554 1.000 15.485 0 601  K5O A C18  1 ? 
HETATM 7892 S S1   . K5O B 2 .   ? -18.797 -24.113 -9.746  1.000 19.148 0 601  K5O A S1   1 ? 
HETATM 7893 C C19  . K5O B 2 .   ? -18.479 -25.284 -8.474  1.000 23.616 0 601  K5O A C19  1 ? 
HETATM 7894 O O1   . K5O B 2 .   ? -19.205 -22.864 -9.172  1.000 22.077 0 601  K5O A O1   1 ? 
HETATM 7895 O O2   . K5O B 2 .   ? -19.619 -24.669 -10.760 1.000 20.984 0 601  K5O A O2   1 ? 
HETATM 7896 C C20  . K5O B 2 .   ? -15.882 -20.760 -13.610 1.000 10.480 0 601  K5O A C20  1 ? 
HETATM 7897 C C21  . K5O B 2 .   ? -16.373 -19.558 -13.150 1.000 10.334 0 601  K5O A C21  1 ? 
HETATM 7898 C C22  . K5O B 2 .   ? -15.324 -19.011 -12.355 1.000 9.878  0 601  K5O A C22  1 ? 
HETATM 7899 C C23  . K5O B 2 .   ? -15.286 -17.809 -11.607 1.000 9.498  0 601  K5O A C23  1 ? 
HETATM 7900 C C24  . K5O B 2 .   ? -16.492 -16.890 -11.603 1.000 9.823  0 601  K5O A C24  1 ? 
HETATM 7901 C C25  . K5O B 2 .   ? -16.491 -21.679 -14.512 1.000 13.215 0 601  K5O A C25  1 ? 
HETATM 7902 N N8   . K5O B 2 .   ? -16.875 -22.475 -15.239 1.000 14.102 0 601  K5O A N8   1 ? 
HETATM 7903 C C26  . K5O B 2 .   ? -13.593 -14.641 -11.785 1.000 9.837  0 601  K5O A C26  1 ? 
HETATM 7904 C C27  . K5O B 2 .   ? -12.672 -13.525 -12.275 1.000 9.691  0 601  K5O A C27  1 ? 
HETATM 7905 C C28  . K5O B 2 .   ? -10.755 -9.223  -12.271 1.000 7.228  0 601  K5O A C28  1 ? 
HETATM 7906 C C29  . K5O B 2 .   ? -9.363  -9.431  -12.630 1.000 8.233  0 601  K5O A C29  1 ? 
HETATM 7907 C C30  . K5O B 2 .   ? -8.730  -8.321  -13.019 1.000 7.860  0 601  K5O A C30  1 ? 
HETATM 7908 C C31  . K5O B 2 .   ? -7.295  -8.127  -13.356 1.000 8.899  0 601  K5O A C31  1 ? 
HETATM 7909 C C32  . K5O B 2 .   ? -6.464  -7.668  -12.181 1.000 8.713  0 601  K5O A C32  1 ? 
HETATM 7910 F F1   . K5O B 2 .   ? -6.829  -6.451  -11.799 1.000 9.542  0 601  K5O A F1   1 ? 
HETATM 7911 F F2   . K5O B 2 .   ? -5.161  -7.625  -12.418 1.000 9.062  0 601  K5O A F2   1 ? 
HETATM 7912 F F3   . K5O B 2 .   ? -6.613  -8.392  -11.075 1.000 10.828 0 601  K5O A F3   1 ? 
HETATM 7913 S S2   . K5O B 2 .   ? -9.800  -6.958  -13.022 1.000 7.830  0 601  K5O A S2   1 ? 
HETATM 7914 C C33  . K5O B 2 .   ? -11.118 -7.914  -12.428 1.000 7.129  0 601  K5O A C33  1 ? 
HETATM 7915 N N9   . K5O B 2 .   ? -12.346 -7.443  -12.215 1.000 7.184  0 601  K5O A N9   1 ? 
HETATM 7916 H H1   . K5O B 2 .   ? -15.261 -9.720  -10.923 1.000 7.557  0 601  K5O A H1   1 c 
HETATM 7917 H H2   . K5O B 2 .   ? -16.328 -8.586  -11.205 1.000 7.566  0 601  K5O A H2   1 c 
HETATM 7918 H H3   . K5O B 2 .   ? -15.513 -8.584  -9.848  1.000 7.559  0 601  K5O A H3   1 c 
HETATM 7919 H H4   . K5O B 2 .   ? -14.636 -7.132  -11.606 1.000 7.301  0 601  K5O A H4   1 c 
HETATM 7920 H H5   . K5O B 2 .   ? -10.683 -11.737 -11.843 1.000 9.361  0 601  K5O A H5   1 c 
HETATM 7921 H H6   . K5O B 2 .   ? -13.323 -12.012 -11.082 1.000 9.909  0 601  K5O A H6   1 c 
HETATM 7922 H H7   . K5O B 2 .   ? -11.134 -13.447 -10.026 1.000 10.289 0 601  K5O A H7   1 c 
HETATM 7923 H H8   . K5O B 2 .   ? -12.003 -12.362 -9.240  1.000 10.245 0 601  K5O A H8   1 c 
HETATM 7924 H H9   . K5O B 2 .   ? -13.903 -13.769 -9.382  1.000 10.247 0 601  K5O A H9   1 c 
HETATM 7925 H H10  . K5O B 2 .   ? -12.730 -14.543 -8.665  1.000 10.249 0 601  K5O A H10  1 c 
HETATM 7926 H H12  . K5O B 2 .   ? -14.859 -15.921 -9.864  1.000 9.867  0 601  K5O A H12  1 c 
HETATM 7927 H H13  . K5O B 2 .   ? -13.639 -16.569 -9.145  1.000 9.951  0 601  K5O A H13  1 c 
HETATM 7928 H H14  . K5O B 2 .   ? -12.248 -18.204 -10.502 1.000 10.219 0 601  K5O A H14  1 c 
HETATM 7929 H H15  . K5O B 2 .   ? -12.302 -20.158 -11.756 1.000 10.101 0 601  K5O A H15  1 c 
HETATM 7930 H H16  . K5O B 2 .   ? -12.877 -21.879 -13.804 1.000 10.289 0 601  K5O A H16  1 c 
HETATM 7931 H H17  . K5O B 2 .   ? -14.188 -22.685 -14.146 1.000 10.296 0 601  K5O A H17  1 c 
HETATM 7932 H H18  . K5O B 2 .   ? -13.004 -22.488 -11.559 1.000 11.581 0 601  K5O A H18  1 c 
HETATM 7933 H H19  . K5O B 2 .   ? -12.748 -24.876 -11.861 1.000 11.922 0 601  K5O A H19  1 c 
HETATM 7934 H H20  . K5O B 2 .   ? -11.829 -23.981 -12.793 1.000 11.868 0 601  K5O A H20  1 c 
HETATM 7935 H H21  . K5O B 2 .   ? -13.140 -24.652 -13.381 1.000 11.864 0 601  K5O A H21  1 c 
HETATM 7936 H H23  . K5O B 2 .   ? -16.175 -23.704 -12.908 1.000 14.561 0 601  K5O A H23  1 c 
HETATM 7937 H H24  . K5O B 2 .   ? -15.308 -24.998 -12.685 1.000 14.509 0 601  K5O A H24  1 c 
HETATM 7938 H H25  . K5O B 2 .   ? -16.439 -25.517 -10.763 1.000 15.860 0 601  K5O A H25  1 c 
HETATM 7939 H H26  . K5O B 2 .   ? -17.525 -25.223 -11.869 1.000 15.894 0 601  K5O A H26  1 c 
HETATM 7940 H H27  . K5O B 2 .   ? -15.952 -23.777 -9.058  1.000 16.513 0 601  K5O A H27  1 c 
HETATM 7941 H H28  . K5O B 2 .   ? -16.784 -22.429 -9.079  1.000 16.546 0 601  K5O A H28  1 c 
HETATM 7942 H H29  . K5O B 2 .   ? -15.769 -21.776 -11.058 1.000 15.319 0 601  K5O A H29  1 c 
HETATM 7943 H H30  . K5O B 2 .   ? -14.637 -22.100 -10.013 1.000 15.371 0 601  K5O A H30  1 c 
HETATM 7944 H H31  . K5O B 2 .   ? -17.532 -25.494 -8.460  1.000 22.349 0 601  K5O A H31  1 c 
HETATM 7945 H H32  . K5O B 2 .   ? -18.989 -26.091 -8.645  1.000 22.370 0 601  K5O A H32  1 c 
HETATM 7946 H H33  . K5O B 2 .   ? -18.741 -24.908 -7.619  1.000 22.370 0 601  K5O A H33  1 c 
HETATM 7947 H H34  . K5O B 2 .   ? -17.221 -19.185 -13.299 1.000 10.228 0 601  K5O A H34  1 c 
HETATM 7948 H H35  . K5O B 2 .   ? -16.255 -16.034 -11.213 1.000 9.748  0 601  K5O A H35  1 c 
HETATM 7949 H H36  . K5O B 2 .   ? -17.205 -17.295 -11.084 1.000 9.809  0 601  K5O A H36  1 c 
HETATM 7950 H H37  . K5O B 2 .   ? -16.796 -16.753 -12.515 1.000 9.745  0 601  K5O A H37  1 c 
HETATM 7951 H H38  . K5O B 2 .   ? -14.486 -14.288 -11.640 1.000 9.685  0 601  K5O A H38  1 c 
HETATM 7952 H H39  . K5O B 2 .   ? -13.647 -15.337 -12.462 1.000 9.672  0 601  K5O A H39  1 c 
HETATM 7953 H H40  . K5O B 2 .   ? -11.800 -13.910 -12.527 1.000 9.799  0 601  K5O A H40  1 c 
HETATM 7954 H H41  . K5O B 2 .   ? -13.062 -13.112 -13.081 1.000 9.799  0 601  K5O A H41  1 c 
HETATM 7955 H H42  . K5O B 2 .   ? -8.943  -10.283 -12.591 1.000 7.927  0 601  K5O A H42  1 c 
HETATM 7956 H H43  . K5O B 2 .   ? -7.227  -7.464  -14.070 1.000 8.602  0 601  K5O A H43  1 c 
HETATM 7957 H H44  . K5O B 2 .   ? -6.933  -8.967  -13.694 1.000 8.603  0 601  K5O A H44  1 c 
HETATM 7958 C C1   . PEG C 3 .   ? 6.269   -8.954  -5.692  1.000 44.067 0 602  PEG A C1   1 ? 
HETATM 7959 O O1   . PEG C 3 .   ? 7.145   -10.043 -5.836  1.000 48.826 0 602  PEG A O1   1 ? 
HETATM 7960 C C2   . PEG C 3 .   ? 6.982   -7.678  -5.386  1.000 41.918 0 602  PEG A C2   1 ? 
HETATM 7961 O O2   . PEG C 3 .   ? 7.108   -7.505  -3.980  1.000 44.749 0 602  PEG A O2   1 ? 
HETATM 7962 C C3   . PEG C 3 .   ? 7.345   -6.151  -3.600  1.000 45.497 0 602  PEG A C3   1 ? 
HETATM 7963 C C4   . PEG C 3 .   ? 8.210   -6.092  -2.381  1.000 48.706 0 602  PEG A C4   1 ? 
HETATM 7964 O O4   . PEG C 3 .   ? 8.756   -4.797  -2.178  1.000 52.332 0 602  PEG A O4   1 ? 
HETATM 7965 H H11  . PEG C 3 .   ? 5.631   -9.149  -4.976  1.000 44.425 0 602  PEG A H11  1 c 
HETATM 7966 H H12  . PEG C 3 .   ? 5.767   -8.846  -6.523  1.000 43.462 0 602  PEG A H12  1 c 
HETATM 7967 H HO1  . PEG C 3 .   ? 6.693   -10.740 -6.002  0.000 49.000 0 602  PEG A HO1  1 c 
HETATM 7968 H H21  . PEG C 3 .   ? 6.483   -6.923  -5.767  1.000 42.757 0 602  PEG A H21  1 c 
HETATM 7969 H H22  . PEG C 3 .   ? 7.874   -7.692  -5.796  1.000 43.034 0 602  PEG A H22  1 c 
HETATM 7970 H H31  . PEG C 3 .   ? 6.488   -5.708  -3.418  1.000 46.016 0 602  PEG A H31  1 c 
HETATM 7971 H H32  . PEG C 3 .   ? 7.784   -5.673  -4.337  1.000 45.976 0 602  PEG A H32  1 c 
HETATM 7972 H H41  . PEG C 3 .   ? 8.942   -6.737  -2.472  1.000 48.780 0 602  PEG A H41  1 c 
HETATM 7973 H H42  . PEG C 3 .   ? 7.679   -6.342  -1.595  1.000 48.780 0 602  PEG A H42  1 c 
HETATM 7974 H HO4  . PEG C 3 .   ? 8.160   -4.209  -2.347  1.000 51.130 0 602  PEG A HO4  1 c 
HETATM 7975 O O1   . PG4 D 4 .   ? -1.582  -26.765 -13.813 1.000 29.856 0 603  PG4 A O1   1 ? 
HETATM 7976 C C1   . PG4 D 4 .   ? -2.812  -27.467 -13.983 1.000 24.614 0 603  PG4 A C1   1 ? 
HETATM 7977 C C2   . PG4 D 4 .   ? -2.754  -28.817 -13.365 1.000 24.594 0 603  PG4 A C2   1 ? 
HETATM 7978 O O2   . PG4 D 4 .   ? -1.842  -29.649 -14.071 1.000 21.349 0 603  PG4 A O2   1 ? 
HETATM 7979 C C3   . PG4 D 4 .   ? -1.607  -30.875 -13.405 1.000 23.607 0 603  PG4 A C3   1 ? 
HETATM 7980 C C4   . PG4 D 4 .   ? -0.702  -31.725 -14.229 1.000 22.974 0 603  PG4 A C4   1 ? 
HETATM 7981 O O3   . PG4 D 4 .   ? 0.582   -31.118 -14.340 1.000 22.203 0 603  PG4 A O3   1 ? 
HETATM 7982 C C5   . PG4 D 4 .   ? 1.511   -31.829 -15.144 1.000 22.524 0 603  PG4 A C5   1 ? 
HETATM 7983 C C6   . PG4 D 4 .   ? 2.537   -30.881 -15.717 1.000 25.118 0 603  PG4 A C6   1 ? 
HETATM 7984 O O4   . PG4 D 4 .   ? 1.836   -29.937 -16.518 1.000 29.924 0 603  PG4 A O4   1 ? 
HETATM 7985 C C7   . PG4 D 4 .   ? 2.647   -29.001 -17.216 1.000 34.562 0 603  PG4 A C7   1 ? 
HETATM 7986 C C8   . PG4 D 4 .   ? 2.039   -28.745 -18.563 1.000 33.663 0 603  PG4 A C8   1 ? 
HETATM 7987 O O5   . PG4 D 4 .   ? 1.786   -27.379 -18.782 1.000 40.642 0 603  PG4 A O5   1 ? 
HETATM 7988 H HO1  . PG4 D 4 .   ? -1.641  -26.002 -14.172 0.000 29.840 0 603  PG4 A HO1  1 c 
HETATM 7989 H H11  . PG4 D 4 .   ? -3.003  -27.555 -14.940 1.000 25.598 0 603  PG4 A H11  1 c 
HETATM 7990 H H12  . PG4 D 4 .   ? -3.534  -26.951 -13.571 1.000 25.747 0 603  PG4 A H12  1 c 
HETATM 7991 H H21  . PG4 D 4 .   ? -3.647  -29.224 -13.378 1.000 23.575 0 603  PG4 A H21  1 c 
HETATM 7992 H H22  . PG4 D 4 .   ? -2.469  -28.737 -12.428 1.000 23.739 0 603  PG4 A H22  1 c 
HETATM 7993 H H31  . PG4 D 4 .   ? -2.458  -31.339 -13.260 1.000 22.958 0 603  PG4 A H31  1 c 
HETATM 7994 H H32  . PG4 D 4 .   ? -1.196  -30.704 -12.529 1.000 22.931 0 603  PG4 A H32  1 c 
HETATM 7995 H H41  . PG4 D 4 .   ? -1.088  -31.845 -15.124 1.000 22.929 0 603  PG4 A H41  1 c 
HETATM 7996 H H42  . PG4 D 4 .   ? -0.612  -32.610 -13.814 1.000 22.930 0 603  PG4 A H42  1 c 
HETATM 7997 H H51  . PG4 D 4 .   ? 1.038   -32.282 -15.876 1.000 23.004 0 603  PG4 A H51  1 c 
HETATM 7998 H H52  . PG4 D 4 .   ? 1.961   -32.512 -14.601 1.000 23.005 0 603  PG4 A H52  1 c 
HETATM 7999 H H61  . PG4 D 4 .   ? 3.187   -31.371 -16.262 1.000 25.606 0 603  PG4 A H61  1 c 
HETATM 8000 H H62  . PG4 D 4 .   ? 3.015   -30.421 -14.993 1.000 25.570 0 603  PG4 A H62  1 c 
HETATM 8001 H H71  . PG4 D 4 .   ? 3.556   -29.356 -17.322 1.000 33.094 0 603  PG4 A H71  1 c 
HETATM 8002 H H72  . PG4 D 4 .   ? 2.700   -28.162 -16.707 1.000 33.246 0 603  PG4 A H72  1 c 
HETATM 8003 H H81  . PG4 D 4 .   ? 1.197   -29.241 -18.638 1.000 35.361 0 603  PG4 A H81  1 c 
HETATM 8004 H H82  . PG4 D 4 .   ? 2.647   -29.073 -19.258 1.000 35.408 0 603  PG4 A H82  1 c 
HETATM 8005 H HO5  . PG4 D 4 .   ? 2.519   -26.955 -18.785 1.000 38.263 0 603  PG4 A HO5  1 c 
HETATM 8006 C C1   . PEG E 3 .   ? -29.855 -1.036  14.566  1.000 46.399 0 604  PEG A C1   1 ? 
HETATM 8007 O O1   . PEG E 3 .   ? -30.235 -0.550  13.272  1.000 48.143 0 604  PEG A O1   1 ? 
HETATM 8008 C C2   . PEG E 3 .   ? -28.656 -1.936  14.513  1.000 39.754 0 604  PEG A C2   1 ? 
HETATM 8009 O O2   . PEG E 3 .   ? -28.527 -2.756  15.685  1.000 32.814 0 604  PEG A O2   1 ? 
HETATM 8010 C C3   . PEG E 3 .   ? -28.676 -4.149  15.407  1.000 25.885 0 604  PEG A C3   1 ? 
HETATM 8011 C C4   . PEG E 3 .   ? -27.577 -4.912  16.021  1.000 27.106 0 604  PEG A C4   1 ? 
HETATM 8012 O O4   . PEG E 3 .   ? -26.927 -5.757  15.196  1.000 22.566 0 604  PEG A O4   1 ? 
HETATM 8013 H H11  . PEG E 3 .   ? -30.608 -1.527  14.956  1.000 45.184 0 604  PEG A H11  1 c 
HETATM 8014 H H12  . PEG E 3 .   ? -29.657 -0.272  15.148  1.000 45.185 0 604  PEG A H12  1 c 
HETATM 8015 H HO1  . PEG E 3 .   ? -30.907 -0.038  13.354  0.000 48.110 0 604  PEG A HO1  1 c 
HETATM 8016 H H21  . PEG E 3 .   ? -27.850 -1.388  14.414  1.000 38.990 0 604  PEG A H21  1 c 
HETATM 8017 H H22  . PEG E 3 .   ? -28.724 -2.508  13.719  1.000 38.847 0 604  PEG A H22  1 c 
HETATM 8018 H H31  . PEG E 3 .   ? -28.671 -4.294  14.439  1.000 27.759 0 604  PEG A H31  1 c 
HETATM 8019 H H32  . PEG E 3 .   ? -29.532 -4.468  15.758  1.000 27.692 0 604  PEG A H32  1 c 
HETATM 8020 H H41  . PEG E 3 .   ? -27.937 -5.435  16.766  1.000 25.670 0 604  PEG A H41  1 c 
HETATM 8021 H H42  . PEG E 3 .   ? -26.926 -4.278  16.382  1.000 25.635 0 604  PEG A H42  1 c 
HETATM 8022 H HO4  . PEG E 3 .   ? -27.459 -6.053  14.609  1.000 23.939 0 604  PEG A HO4  1 c 
HETATM 8023 C C1   . EDO F 5 .   ? -3.973  2.982   -26.301 1.000 11.273 0 605  EDO A C1   1 ? 
HETATM 8024 O O1   . EDO F 5 .   ? -5.024  2.021   -26.572 1.000 24.433 0 605  EDO A O1   1 ? 
HETATM 8025 C C2   . EDO F 5 .   ? -2.779  2.757   -27.023 1.000 23.504 0 605  EDO A C2   1 ? 
HETATM 8026 O O2   . EDO F 5 .   ? -2.194  1.710   -26.336 1.000 29.403 0 605  EDO A O2   1 ? 
HETATM 8027 H H11  . EDO F 5 .   ? -3.770  2.965   -25.343 1.000 16.155 0 605  EDO A H11  1 c 
HETATM 8028 H H12  . EDO F 5 .   ? -4.305  3.877   -26.521 1.000 16.069 0 605  EDO A H12  1 c 
HETATM 8029 H HO1  . EDO F 5 .   ? -5.706  2.216   -26.113 0.000 24.430 0 605  EDO A HO1  1 c 
HETATM 8030 H H21  . EDO F 5 .   ? -2.210  3.551   -27.012 1.000 20.535 0 605  EDO A H21  1 c 
HETATM 8031 H H22  . EDO F 5 .   ? -2.978  2.499   -27.948 1.000 20.711 0 605  EDO A H22  1 c 
HETATM 8032 H HO2  . EDO F 5 .   ? -2.493  0.974   -26.635 1.000 27.097 0 605  EDO A HO2  1 c 
HETATM 8033 S S    . DMS G 6 .   ? -14.455 0.122   15.698  1.000 37.048 0 606  DMS A S    1 ? 
HETATM 8034 O O    . DMS G 6 .   ? -15.818 -0.352  15.203  1.000 39.096 0 606  DMS A O    1 ? 
HETATM 8035 C C1   . DMS G 6 .   ? -13.563 0.595   14.251  1.000 32.650 0 606  DMS A C1   1 ? 
HETATM 8036 C C2   . DMS G 6 .   ? -13.547 -1.330  16.147  1.000 35.807 0 606  DMS A C2   1 ? 
HETATM 8037 H H11  . DMS G 6 .   ? -12.664 0.853   14.497  1.000 33.526 0 606  DMS A H11  1 c 
HETATM 8038 H H12  . DMS G 6 .   ? -14.010 1.340   13.828  1.000 33.280 0 606  DMS A H12  1 c 
HETATM 8039 H H13  . DMS G 6 .   ? -13.530 -0.151  13.639  1.000 33.185 0 606  DMS A H13  1 c 
HETATM 8040 H H21  . DMS G 6 .   ? -13.471 -1.910  15.378  1.000 35.882 0 606  DMS A H21  1 c 
HETATM 8041 H H22  . DMS G 6 .   ? -14.011 -1.793  16.856  1.000 36.060 0 606  DMS A H22  1 c 
HETATM 8042 H H23  . DMS G 6 .   ? -12.664 -1.076  16.449  1.000 36.060 0 606  DMS A H23  1 c 
HETATM 8043 S S    . DMS H 6 .   ? -9.794  -7.975  -9.147  1.000 30.375 0 607  DMS A S    1 ? 
HETATM 8044 O O    . DMS H 6 .   ? -10.025 -9.468  -8.881  1.000 35.766 0 607  DMS A O    1 ? 
HETATM 8045 C C1   . DMS H 6 .   ? -11.373 -7.138  -8.919  1.000 21.688 0 607  DMS A C1   1 ? 
HETATM 8046 C C2   . DMS H 6 .   ? -9.315  -7.334  -7.614  1.000 24.738 0 607  DMS A C2   1 ? 
HETATM 8047 H H11  . DMS H 6 .   ? -11.245 -6.183  -8.998  1.000 23.530 0 607  DMS A H11  1 c 
HETATM 8048 H H12  . DMS H 6 .   ? -11.727 -7.346  -8.044  1.000 23.537 0 607  DMS A H12  1 c 
HETATM 8049 H H13  . DMS H 6 .   ? -11.994 -7.437  -9.595  1.000 23.219 0 607  DMS A H13  1 c 
HETATM 8050 H H21  . DMS H 6 .   ? -8.402  -7.594  -7.430  1.000 25.984 0 607  DMS A H21  1 c 
HETATM 8051 H H22  . DMS H 6 .   ? -9.895  -7.682  -6.922  1.000 26.014 0 607  DMS A H22  1 c 
HETATM 8052 H H23  . DMS H 6 .   ? -9.377  -6.369  -7.634  1.000 26.016 0 607  DMS A H23  1 c 
HETATM 8053 O O    . HOH I 7 .   ? -10.430 -14.394 -29.621 1.000 13.866 0 701  HOH A O    1 ? 
HETATM 8054 O O    . HOH I 7 .   ? 2.402   -5.256  8.469   1.000 34.813 0 702  HOH A O    1 ? 
HETATM 8055 O O    . HOH I 7 .   ? -13.184 -28.660 -9.426  1.000 40.066 0 703  HOH A O    1 ? 
HETATM 8056 O O    . HOH I 7 .   ? -32.770 -15.580 -0.607  1.000 40.089 0 704  HOH A O    1 ? 
HETATM 8057 O O    . HOH I 7 .   ? -12.475 -16.365 -31.600 1.000 28.399 0 705  HOH A O    1 ? 
HETATM 8058 O O    . HOH I 7 .   ? 1.548   -14.057 -21.379 1.000 14.942 0 706  HOH A O    1 ? 
HETATM 8059 O O    . HOH I 7 .   ? 3.595   -25.608 -22.084 1.000 35.587 0 707  HOH A O    1 ? 
HETATM 8060 O O    . HOH I 7 .   ? 7.807   -13.739 -18.073 1.000 35.737 0 708  HOH A O    1 ? 
HETATM 8061 O O    . HOH I 7 .   ? -29.091 -24.984 -25.310 1.000 37.331 0 709  HOH A O    1 ? 
HETATM 8062 O O    . HOH I 7 .   ? -21.239 -16.510 0.616   1.000 38.279 0 710  HOH A O    1 ? 
HETATM 8063 O O    . HOH I 7 .   ? -3.402  -11.252 -2.639  1.000 39.358 0 711  HOH A O    1 ? 
HETATM 8064 O O    . HOH I 7 .   ? -13.361 -4.954  15.589  1.000 22.117 0 712  HOH A O    1 ? 
HETATM 8065 O O    . HOH I 7 .   ? -13.852 16.736  -5.737  1.000 43.911 0 713  HOH A O    1 ? 
HETATM 8066 O O    . HOH I 7 .   ? 2.321   -11.765 -22.908 1.000 16.561 0 714  HOH A O    1 ? 
HETATM 8067 O O    . HOH I 7 .   ? 7.940   -13.089 -8.442  1.000 38.250 0 715  HOH A O    1 ? 
HETATM 8068 O O    . HOH I 7 .   ? 8.053   16.443  -18.601 1.000 26.816 0 716  HOH A O    1 ? 
HETATM 8069 O O    . HOH I 7 .   ? -25.718 -48.706 -32.044 1.000 40.919 0 717  HOH A O    1 ? 
HETATM 8070 O O    . HOH I 7 .   ? -28.607 -21.665 -24.654 1.000 37.379 0 718  HOH A O    1 ? 
HETATM 8071 O O    . HOH I 7 .   ? -13.661 -25.427 -9.503  1.000 27.313 0 719  HOH A O    1 ? 
HETATM 8072 O O    . HOH I 7 .   ? -5.918  -25.455 -40.594 1.000 23.406 0 720  HOH A O    1 ? 
HETATM 8073 O O    . HOH I 7 .   ? 11.968  12.436  -8.398  1.000 35.658 0 721  HOH A O    1 ? 
HETATM 8074 O O    . HOH I 7 .   ? -25.625 -32.957 -7.535  1.000 32.263 0 722  HOH A O    1 ? 
HETATM 8075 O O    . HOH I 7 .   ? 0.831   -28.051 -21.038 1.000 31.913 0 723  HOH A O    1 ? 
HETATM 8076 O O    . HOH I 7 .   ? -28.869 -47.073 -10.465 1.000 16.678 0 724  HOH A O    1 ? 
HETATM 8077 O O    . HOH I 7 .   ? -5.752  -26.586 -12.751 1.000 28.131 0 725  HOH A O    1 ? 
HETATM 8078 O O    . HOH I 7 .   ? 13.147  12.126  -20.644 1.000 29.389 0 726  HOH A O    1 ? 
HETATM 8079 O O    . HOH I 7 .   ? 11.167  10.425  -3.460  1.000 27.047 0 727  HOH A O    1 ? 
HETATM 8080 O O    . HOH I 7 .   ? -30.181 -43.062 -30.788 1.000 32.976 0 728  HOH A O    1 ? 
HETATM 8081 O O    . HOH I 7 .   ? -0.266  19.090  -13.336 1.000 35.326 0 729  HOH A O    1 ? 
HETATM 8082 O O    . HOH I 7 .   ? -24.146 9.258   6.885   1.000 30.446 0 730  HOH A O    1 ? 
HETATM 8083 O O    . HOH I 7 .   ? -31.435 -25.722 -21.820 1.000 27.641 0 731  HOH A O    1 ? 
HETATM 8084 O O    . HOH I 7 .   ? 0.884   -25.016 -19.266 1.000 39.789 0 732  HOH A O    1 ? 
HETATM 8085 O O    . HOH I 7 .   ? -33.737 -12.507 -1.736  1.000 38.243 0 733  HOH A O    1 ? 
HETATM 8086 O O    . HOH I 7 .   ? -15.419 -43.710 -35.075 1.000 26.744 0 734  HOH A O    1 ? 
HETATM 8087 O O    . HOH I 7 .   ? -18.675 -35.048 -43.162 1.000 41.446 0 735  HOH A O    1 ? 
HETATM 8088 O O    . HOH I 7 .   ? -27.900 -16.375 0.560   1.000 32.485 0 736  HOH A O    1 ? 
HETATM 8089 O O    . HOH I 7 .   ? -22.639 -18.978 -23.937 1.000 23.941 0 737  HOH A O    1 ? 
HETATM 8090 O O    . HOH I 7 .   ? -31.126 0.754   -14.034 1.000 28.609 0 738  HOH A O    1 ? 
HETATM 8091 O O    . HOH I 7 .   ? -30.621 3.954   -14.631 1.000 35.644 0 739  HOH A O    1 ? 
HETATM 8092 O O    . HOH I 7 .   ? -4.531  16.715  -15.798 1.000 36.571 0 740  HOH A O    1 ? 
HETATM 8093 O O    . HOH I 7 .   ? -3.517  -12.166 8.348   1.000 37.072 0 741  HOH A O    1 ? 
HETATM 8094 O O    . HOH I 7 .   ? -15.631 -9.566  -6.620  1.000 23.831 0 742  HOH A O    1 ? 
HETATM 8095 O O    . HOH I 7 .   ? 12.135  -6.045  -17.470 1.000 34.601 0 743  HOH A O    1 ? 
HETATM 8096 O O    . HOH I 7 .   ? -15.811 -23.744 -36.496 1.000 27.777 0 744  HOH A O    1 ? 
HETATM 8097 O O    . HOH I 7 .   ? -18.721 -19.420 -10.863 1.000 31.999 0 745  HOH A O    1 ? 
HETATM 8098 O O    . HOH I 7 .   ? -18.775 -17.515 -8.651  1.000 28.436 0 746  HOH A O    1 ? 
HETATM 8099 O O    . HOH I 7 .   ? -26.795 7.038   9.663   1.000 33.245 0 747  HOH A O    1 ? 
HETATM 8100 O O    . HOH I 7 .   ? 0.007   -38.792 -33.389 1.000 31.488 0 748  HOH A O    1 ? 
HETATM 8101 O O    . HOH I 7 .   ? -37.105 -14.467 -11.581 1.000 44.859 0 749  HOH A O    1 ? 
HETATM 8102 O O    . HOH I 7 .   ? -9.780  -19.813 -9.816  1.000 34.892 0 750  HOH A O    1 ? 
HETATM 8103 O O    . HOH I 7 .   ? -9.068  -33.443 -21.241 1.000 8.899  0 751  HOH A O    1 ? 
HETATM 8104 O O    . HOH I 7 .   ? -12.971 -48.664 -31.862 1.000 35.207 0 752  HOH A O    1 ? 
HETATM 8105 O O    . HOH I 7 .   ? 12.466  21.947  -8.894  1.000 46.600 0 753  HOH A O    1 ? 
HETATM 8106 O O    . HOH I 7 .   ? -3.419  -20.233 -31.567 1.000 18.814 0 754  HOH A O    1 ? 
HETATM 8107 O O    . HOH I 7 .   ? -3.745  -21.997 -36.541 1.000 35.642 0 755  HOH A O    1 ? 
HETATM 8108 O O    . HOH I 7 .   ? 13.678  10.347  -7.402  1.000 32.774 0 756  HOH A O    1 ? 
HETATM 8109 O O    . HOH I 7 .   ? -7.725  13.149  -11.862 1.000 24.125 0 757  HOH A O    1 ? 
HETATM 8110 O O    . HOH I 7 .   ? -30.960 -32.079 -29.761 1.000 26.989 0 758  HOH A O    1 ? 
HETATM 8111 O O    . HOH I 7 .   ? -18.316 -42.580 -6.787  1.000 38.582 0 759  HOH A O    1 ? 
HETATM 8112 O O    . HOH I 7 .   ? -21.632 -46.115 -32.547 1.000 28.336 0 760  HOH A O    1 ? 
HETATM 8113 O O    . HOH I 7 .   ? 5.570   -15.429 -27.323 1.000 34.766 0 761  HOH A O    1 ? 
HETATM 8114 O O    . HOH I 7 .   ? -18.102 -11.200 -3.987  1.000 21.188 0 762  HOH A O    1 ? 
HETATM 8115 O O    . HOH I 7 .   ? 12.809  17.301  -4.980  1.000 33.173 0 763  HOH A O    1 ? 
HETATM 8116 O O    . HOH I 7 .   ? -18.202 -1.611  18.448  1.000 42.336 0 764  HOH A O    1 ? 
HETATM 8117 O O    . HOH I 7 .   ? -6.054  -25.119 -38.087 1.000 16.358 0 765  HOH A O    1 ? 
HETATM 8118 O O    . HOH I 7 .   ? 2.414   -18.118 -34.088 1.000 39.438 0 766  HOH A O    1 ? 
HETATM 8119 O O    . HOH I 7 .   ? -20.763 -1.053  19.159  1.000 33.822 0 767  HOH A O    1 ? 
HETATM 8120 O O    . HOH I 7 .   ? -13.635 -13.738 -1.373  1.000 29.037 0 768  HOH A O    1 ? 
HETATM 8121 O O    . HOH I 7 .   ? -22.385 14.864  -5.367  1.000 29.971 0 769  HOH A O    1 ? 
HETATM 8122 O O    . HOH I 7 .   ? -28.454 -2.528  5.618   1.000 19.798 0 770  HOH A O    1 ? 
HETATM 8123 O O    . HOH I 7 .   ? -35.949 -4.115  -4.271  1.000 37.873 0 771  HOH A O    1 ? 
HETATM 8124 O O    . HOH I 7 .   ? -16.544 -12.067 -9.089  1.000 16.259 0 772  HOH A O    1 ? 
HETATM 8125 O O    . HOH I 7 .   ? -1.781  -15.977 -16.017 1.000 11.013 0 773  HOH A O    1 ? 
HETATM 8126 O O    . HOH I 7 .   ? -11.219 15.785  -3.311  1.000 35.089 0 774  HOH A O    1 ? 
HETATM 8127 O O    . HOH I 7 .   ? -9.684  -0.449  -2.619  1.000 9.261  0 775  HOH A O    1 ? 
HETATM 8128 O O    . HOH I 7 .   ? 10.641  14.779  -2.700  1.000 37.347 0 776  HOH A O    1 ? 
HETATM 8129 O O    . HOH I 7 .   ? -20.055 -7.715  19.851  1.000 37.238 0 777  HOH A O    1 ? 
HETATM 8130 O O    . HOH I 7 .   ? -16.759 5.764   16.761  1.000 37.094 0 778  HOH A O    1 ? 
HETATM 8131 O O    . HOH I 7 .   ? -23.493 -17.302 -6.774  1.000 19.641 0 779  HOH A O    1 ? 
HETATM 8132 O O    . HOH I 7 .   ? 11.644  6.900   -10.587 1.000 26.636 0 780  HOH A O    1 ? 
HETATM 8133 O O    . HOH I 7 .   ? -15.247 -17.336 2.433   1.000 29.907 0 781  HOH A O    1 ? 
HETATM 8134 O O    . HOH I 7 .   ? 11.417  -2.178  -16.607 1.000 33.338 0 782  HOH A O    1 ? 
HETATM 8135 O O    . HOH I 7 .   ? 4.770   -5.261  -20.600 1.000 11.028 0 783  HOH A O    1 ? 
HETATM 8136 O O    . HOH I 7 .   ? -18.328 -13.683 -7.864  1.000 18.316 0 784  HOH A O    1 ? 
HETATM 8137 O O    . HOH I 7 .   ? 11.139  6.699   -5.452  1.000 30.810 0 785  HOH A O    1 ? 
HETATM 8138 O O    . HOH I 7 .   ? -14.418 5.588   13.127  1.000 16.202 0 786  HOH A O    1 ? 
HETATM 8139 O O    . HOH I 7 .   ? -10.261 -22.779 -10.519 1.000 22.730 0 787  HOH A O    1 ? 
HETATM 8140 O O    . HOH I 7 .   ? -4.361  -28.924 -33.967 1.000 11.390 0 788  HOH A O    1 ? 
HETATM 8141 O O    . HOH I 7 .   ? -17.428 -2.462  14.998  1.000 25.477 0 789  HOH A O    1 ? 
HETATM 8142 O O    . HOH I 7 .   ? -28.243 -36.376 -7.857  1.000 14.640 0 790  HOH A O    1 ? 
HETATM 8143 O O    . HOH I 7 .   ? -13.312 -23.961 -32.541 1.000 17.137 0 791  HOH A O    1 ? 
HETATM 8144 O O    . HOH I 7 .   ? -5.066  -11.539 5.087   1.000 38.687 0 792  HOH A O    1 ? 
HETATM 8145 O O    . HOH I 7 .   ? -14.503 14.162  -5.363  1.000 19.165 0 793  HOH A O    1 ? 
HETATM 8146 O O    . HOH I 7 .   ? -17.911 11.328  14.178  1.000 25.165 0 794  HOH A O    1 ? 
HETATM 8147 O O    . HOH I 7 .   ? -31.920 -3.362  -15.777 1.000 27.708 0 795  HOH A O    1 ? 
HETATM 8148 O O    . HOH I 7 .   ? -37.198 -2.703  -9.658  1.000 40.552 0 796  HOH A O    1 ? 
HETATM 8149 O O    . HOH I 7 .   ? -29.208 3.284   -7.931  1.000 22.573 0 797  HOH A O    1 ? 
HETATM 8150 O O    . HOH I 7 .   ? 5.958   -5.898  -14.176 1.000 21.892 0 798  HOH A O    1 ? 
HETATM 8151 O O    . HOH I 7 .   ? -3.055  -28.255 -31.601 1.000 10.572 0 799  HOH A O    1 ? 
HETATM 8152 O O    . HOH I 7 .   ? -3.308  -16.199 -32.447 1.000 34.658 0 800  HOH A O    1 ? 
HETATM 8153 O O    . HOH I 7 .   ? -11.799 -34.372 -40.649 1.000 25.844 0 801  HOH A O    1 ? 
HETATM 8154 O O    . HOH I 7 .   ? -22.587 -20.594 -29.539 1.000 45.971 0 802  HOH A O    1 ? 
HETATM 8155 O O    . HOH I 7 .   ? -1.660  -7.695  -11.834 1.000 22.528 0 803  HOH A O    1 ? 
HETATM 8156 O O    . HOH I 7 .   ? -9.500  -3.720  2.096   1.000 13.525 0 804  HOH A O    1 ? 
HETATM 8157 O O    . HOH I 7 .   ? 12.945  4.205   -12.931 1.000 32.947 0 805  HOH A O    1 ? 
HETATM 8158 O O    . HOH I 7 .   ? -5.666  17.335  -1.013  1.000 49.954 0 806  HOH A O    1 ? 
HETATM 8159 O O    . HOH I 7 .   ? 0.485   -30.859 -27.368 1.000 21.750 0 807  HOH A O    1 ? 
HETATM 8160 O O    . HOH I 7 .   ? 1.521   -9.125  -33.825 1.000 23.452 0 808  HOH A O    1 ? 
HETATM 8161 O O    . HOH I 7 .   ? -6.886  -18.507 -12.344 1.000 32.688 0 809  HOH A O    1 ? 
HETATM 8162 O O    . HOH I 7 .   ? -21.298 3.161   -24.362 1.000 26.641 0 810  HOH A O    1 ? 
HETATM 8163 O O    . HOH I 7 .   ? -18.252 -12.752 -31.770 1.000 25.546 0 811  HOH A O    1 ? 
HETATM 8164 O O    . HOH I 7 .   ? -24.473 -42.811 -21.954 1.000 22.696 0 812  HOH A O    1 ? 
HETATM 8165 O O    . HOH I 7 .   ? -0.857  -29.620 -16.817 1.000 11.983 0 813  HOH A O    1 ? 
HETATM 8166 O O    . HOH I 7 .   ? -2.183  -9.987  -26.308 1.000 8.669  0 814  HOH A O    1 ? 
HETATM 8167 O O    . HOH I 7 .   ? 12.483  10.076  -11.924 1.000 31.363 0 815  HOH A O    1 ? 
HETATM 8168 O O    . HOH I 7 .   ? -25.087 -14.423 -24.821 1.000 22.165 0 816  HOH A O    1 ? 
HETATM 8169 O O    . HOH I 7 .   ? -28.766 -37.486 -17.189 1.000 12.960 0 817  HOH A O    1 ? 
HETATM 8170 O O    . HOH I 7 .   ? -26.934 -0.747  16.529  1.000 36.336 0 818  HOH A O    1 ? 
HETATM 8171 O O    . HOH I 7 .   ? -9.759  11.660  -15.013 1.000 20.573 0 819  HOH A O    1 ? 
HETATM 8172 O O    . HOH I 7 .   ? -31.901 -11.271 -9.362  1.000 15.353 0 820  HOH A O    1 ? 
HETATM 8173 O O    . HOH I 7 .   ? -11.338 -17.644 -35.569 1.000 42.438 0 821  HOH A O    1 ? 
HETATM 8174 O O    . HOH I 7 .   ? -13.601 -33.820 -20.343 1.000 11.092 0 822  HOH A O    1 ? 
HETATM 8175 O O    . HOH I 7 .   ? -8.281  13.741  11.676  1.000 20.438 0 823  HOH A O    1 ? 
HETATM 8176 O O    . HOH I 7 .   ? 1.605   -3.158  -14.370 1.000 9.074  0 824  HOH A O    1 ? 
HETATM 8177 O O    . HOH I 7 .   ? 2.676   -32.044 -24.354 1.000 40.333 0 825  HOH A O    1 ? 
HETATM 8178 O O    . HOH I 7 .   ? -5.176  -30.553 -11.215 1.000 38.916 0 826  HOH A O    1 ? 
HETATM 8179 O O    . HOH I 7 .   ? -15.949 -9.869  -32.501 1.000 41.332 0 827  HOH A O    1 ? 
HETATM 8180 O O    . HOH I 7 .   ? -31.229 -17.550 -6.205  1.000 30.717 0 828  HOH A O    1 ? 
HETATM 8181 O O    . HOH I 7 .   ? -3.228  -17.498 -24.551 1.000 10.859 0 829  HOH A O    1 ? 
HETATM 8182 O O    . HOH I 7 .   ? -14.190 -14.460 -30.089 1.000 23.919 0 830  HOH A O    1 ? 
HETATM 8183 O O    . HOH I 7 .   ? -2.414  -1.637  -26.627 1.000 18.284 0 831  HOH A O    1 ? 
HETATM 8184 O O    . HOH I 7 .   ? -7.337  -14.103 -13.664 1.000 15.434 0 832  HOH A O    1 ? 
HETATM 8185 O O    . HOH I 7 .   ? -34.839 -11.520 -10.625 1.000 26.429 0 833  HOH A O    1 ? 
HETATM 8186 O O    . HOH I 7 .   ? -6.039  9.293   -20.345 1.000 18.208 0 834  HOH A O    1 ? 
HETATM 8187 O O    . HOH I 7 .   ? -23.613 -6.721  11.693  1.000 13.195 0 835  HOH A O    1 ? 
HETATM 8188 O O    . HOH I 7 .   ? -24.301 2.123   13.492  1.000 19.626 0 836  HOH A O    1 ? 
HETATM 8189 O O    . HOH I 7 .   ? 1.355   -28.934 -12.922 1.000 23.702 0 837  HOH A O    1 ? 
HETATM 8190 O O    . HOH I 7 .   ? -2.322  -34.858 -33.841 1.000 11.557 0 838  HOH A O    1 ? 
HETATM 8191 O O    . HOH I 7 .   ? -32.850 1.802   -9.662  1.000 34.085 0 839  HOH A O    1 ? 
HETATM 8192 O O    . HOH I 7 .   ? -7.159  -2.883  -5.405  1.000 9.586  0 840  HOH A O    1 ? 
HETATM 8193 O O    . HOH I 7 .   ? 5.393   -14.115 -22.954 1.000 30.583 0 841  HOH A O    1 ? 
HETATM 8194 O O    . HOH I 7 .   ? -19.815 13.164  2.845   1.000 17.879 0 842  HOH A O    1 ? 
HETATM 8195 O O    . HOH I 7 .   ? -14.198 -23.728 -29.935 1.000 12.135 0 843  HOH A O    1 ? 
HETATM 8196 O O    . HOH I 7 .   ? -9.797  -8.474  -3.389  1.000 10.805 0 844  HOH A O    1 ? 
HETATM 8197 O O    . HOH I 7 .   ? -24.354 -0.688  17.331  1.000 30.464 0 845  HOH A O    1 ? 
HETATM 8198 O O    . HOH I 7 .   ? 7.603   -11.305 0.078   1.000 44.639 0 846  HOH A O    1 ? 
HETATM 8199 O O    . HOH I 7 .   ? 4.402   15.598  -19.390 1.000 18.892 0 847  HOH A O    1 ? 
HETATM 8200 O O    . HOH I 7 .   ? -11.629 -25.701 -40.699 1.000 24.929 0 848  HOH A O    1 ? 
HETATM 8201 O O    . HOH I 7 .   ? -17.768 -38.806 -6.639  1.000 38.668 0 849  HOH A O    1 ? 
HETATM 8202 O O    . HOH I 7 .   ? -9.858  18.977  4.674   1.000 31.673 0 850  HOH A O    1 ? 
HETATM 8203 O O    . HOH I 7 .   ? -16.405 -50.175 -31.224 1.000 32.602 0 851  HOH A O    1 ? 
HETATM 8204 O O    . HOH I 7 .   ? 6.678   2.266   4.193   1.000 33.170 0 852  HOH A O    1 ? 
HETATM 8205 O O    . HOH I 7 .   ? -6.838  -4.205  4.952   1.000 17.767 0 853  HOH A O    1 ? 
HETATM 8206 O O    . HOH I 7 .   ? 4.299   15.581  2.893   1.000 33.232 0 854  HOH A O    1 ? 
HETATM 8207 O O    . HOH I 7 .   ? 9.647   16.443  0.172   1.000 32.592 0 855  HOH A O    1 ? 
HETATM 8208 O O    . HOH I 7 .   ? -1.978  -44.311 -27.172 1.000 29.236 0 856  HOH A O    1 ? 
HETATM 8209 O O    . HOH I 7 .   ? -24.626 8.459   -14.984 1.000 27.687 0 857  HOH A O    1 ? 
HETATM 8210 O O    . HOH I 7 .   ? -21.407 -46.827 -27.145 1.000 24.726 0 858  HOH A O    1 ? 
HETATM 8211 O O    . HOH I 7 .   ? -22.705 3.684   -19.912 1.000 28.219 0 859  HOH A O    1 ? 
HETATM 8212 O O    . HOH I 7 .   ? -6.110  -5.028  7.474   1.000 18.941 0 860  HOH A O    1 ? 
HETATM 8213 O O    . HOH I 7 .   ? -6.935  15.011  -10.097 1.000 29.763 0 861  HOH A O    1 ? 
HETATM 8214 O O    . HOH I 7 .   ? -18.268 -3.539  21.392  1.000 35.353 0 862  HOH A O    1 ? 
HETATM 8215 O O    . HOH I 7 .   ? 4.435   -23.105 -32.450 1.000 38.274 0 863  HOH A O    1 ? 
HETATM 8216 O O    . HOH I 7 .   ? -37.225 -8.794  -11.050 1.000 31.087 0 864  HOH A O    1 ? 
HETATM 8217 O O    . HOH I 7 .   ? -30.800 -27.885 -20.226 1.000 19.779 0 865  HOH A O    1 ? 
HETATM 8218 O O    . HOH I 7 .   ? -15.121 -37.795 -17.945 1.000 11.949 0 866  HOH A O    1 ? 
HETATM 8219 O O    . HOH I 7 .   ? -2.731  11.733  9.594   1.000 18.923 0 867  HOH A O    1 ? 
HETATM 8220 O O    . HOH I 7 .   ? -8.870  -23.396 -39.077 1.000 23.778 0 868  HOH A O    1 ? 
HETATM 8221 O O    . HOH I 7 .   ? -7.516  -7.950  -4.956  1.000 14.337 0 869  HOH A O    1 ? 
HETATM 8222 O O    . HOH I 7 .   ? -5.855  -32.656 -39.473 1.000 8.544  0 870  HOH A O    1 ? 
HETATM 8223 O O    . HOH I 7 .   ? -2.162  -23.557 -37.685 1.000 25.782 0 871  HOH A O    1 ? 
HETATM 8224 O O    . HOH I 7 .   ? -4.185  -8.683  -8.084  1.000 14.587 0 872  HOH A O    1 ? 
HETATM 8225 O O    . HOH I 7 .   ? -12.630 -44.684 -31.905 1.000 18.001 0 873  HOH A O    1 ? 
HETATM 8226 O O    . HOH I 7 .   ? 0.885   3.147   -27.232 1.000 13.409 0 874  HOH A O    1 ? 
HETATM 8227 O O    . HOH I 7 .   ? -25.780 -41.671 -24.138 1.000 14.276 0 875  HOH A O    1 ? 
HETATM 8228 O O    . HOH I 7 .   ? 11.084  8.051   -12.997 1.000 18.716 0 876  HOH A O    1 ? 
HETATM 8229 O O    . HOH I 7 .   ? -5.946  -8.981  -1.146  1.000 11.247 0 877  HOH A O    1 ? 
HETATM 8230 O O    . HOH I 7 .   ? -28.801 3.891   7.391   1.000 36.386 0 878  HOH A O    1 ? 
HETATM 8231 O O    . HOH I 7 .   ? -16.318 2.855   14.972  1.000 30.404 0 879  HOH A O    1 ? 
HETATM 8232 O O    . HOH I 7 .   ? -35.163 -4.607  -13.028 1.000 22.546 0 880  HOH A O    1 ? 
HETATM 8233 O O    . HOH I 7 .   ? -25.636 10.735  -1.747  1.000 20.308 0 881  HOH A O    1 ? 
HETATM 8234 O O    . HOH I 7 .   ? -17.199 -38.573 -16.391 1.000 13.015 0 882  HOH A O    1 ? 
HETATM 8235 O O    . HOH I 7 .   ? -25.854 -44.262 -17.703 1.000 22.412 0 883  HOH A O    1 ? 
HETATM 8236 O O    . HOH I 7 .   ? -32.596 -33.852 -18.284 1.000 32.844 0 884  HOH A O    1 ? 
HETATM 8237 O O    . HOH I 7 .   ? -30.824 -1.241  4.442   1.000 32.530 0 885  HOH A O    1 ? 
HETATM 8238 O O    . HOH I 7 .   ? -21.963 9.209   -12.421 1.000 20.335 0 886  HOH A O    1 ? 
HETATM 8239 O O    . HOH I 7 .   ? -15.670 -12.106 -24.971 1.000 8.214  0 887  HOH A O    1 ? 
HETATM 8240 O O    . HOH I 7 .   ? -19.389 15.535  8.921   1.000 23.899 0 888  HOH A O    1 ? 
HETATM 8241 O O    . HOH I 7 .   ? 9.007   14.317  -17.016 1.000 23.530 0 889  HOH A O    1 ? 
HETATM 8242 O O    . HOH I 7 .   ? -24.106 10.644  9.793   1.000 31.831 0 890  HOH A O    1 ? 
HETATM 8243 O O    . HOH I 7 .   ? -28.173 -8.373  -0.397  1.000 31.362 0 891  HOH A O    1 ? 
HETATM 8244 O O    . HOH I 7 .   ? -34.720 -10.672 -8.000  1.000 21.330 0 892  HOH A O    1 ? 
HETATM 8245 O O    . HOH I 7 .   ? -7.310  16.317  3.396   1.000 35.993 0 893  HOH A O    1 ? 
HETATM 8246 O O    . HOH I 7 .   ? 2.160   8.056   7.243   1.000 30.960 0 894  HOH A O    1 ? 
HETATM 8247 O O    . HOH I 7 .   ? -24.643 -33.475 -13.504 1.000 18.303 0 895  HOH A O    1 ? 
HETATM 8248 O O    . HOH I 7 .   ? -0.236  -18.002 -34.043 1.000 38.653 0 896  HOH A O    1 ? 
HETATM 8249 O O    . HOH I 7 .   ? -20.388 -17.918 -11.831 1.000 11.778 0 897  HOH A O    1 ? 
HETATM 8250 O O    . HOH I 7 .   ? 5.974   -9.413  -29.111 1.000 13.147 0 898  HOH A O    1 ? 
HETATM 8251 O O    . HOH I 7 .   ? -27.561 -19.455 -20.767 1.000 20.084 0 899  HOH A O    1 ? 
HETATM 8252 O O    . HOH I 7 .   ? 1.153   -31.780 -30.262 1.000 24.079 0 900  HOH A O    1 ? 
HETATM 8253 O O    . HOH I 7 .   ? -7.896  11.826  -4.447  1.000 24.814 0 901  HOH A O    1 ? 
HETATM 8254 O O    . HOH I 7 .   ? -6.481  -5.572  -5.873  1.000 10.290 0 902  HOH A O    1 ? 
HETATM 8255 O O    . HOH I 7 .   ? 0.315   12.066  -29.851 1.000 21.047 0 903  HOH A O    1 ? 
HETATM 8256 O O    . HOH I 7 .   ? 6.239   -4.393  -24.113 1.000 20.662 0 904  HOH A O    1 ? 
HETATM 8257 O O    . HOH I 7 .   ? -13.901 -0.369  -26.145 1.000 29.374 0 905  HOH A O    1 ? 
HETATM 8258 O O    . HOH I 7 .   ? -4.469  13.026  -22.091 1.000 40.098 0 906  HOH A O    1 ? 
HETATM 8259 O O    . HOH I 7 .   ? -32.608 -38.713 -21.404 1.000 18.940 0 907  HOH A O    1 ? 
HETATM 8260 O O    . HOH I 7 .   ? -24.705 9.438   -8.116  1.000 22.841 0 908  HOH A O    1 ? 
HETATM 8261 O O    . HOH I 7 .   ? -16.821 -43.173 -20.089 1.000 23.696 0 909  HOH A O    1 ? 
HETATM 8262 O O    . HOH I 7 .   ? -14.382 -29.658 -39.894 1.000 21.076 0 910  HOH A O    1 ? 
HETATM 8263 O O    . HOH I 7 .   ? -32.981 -14.432 -17.762 1.000 43.905 0 911  HOH A O    1 ? 
HETATM 8264 O O    . HOH I 7 .   ? -1.025  18.638  -10.999 1.000 28.977 0 912  HOH A O    1 ? 
HETATM 8265 O O    . HOH I 7 .   ? -15.708 -4.540  14.172  1.000 16.017 0 913  HOH A O    1 ? 
HETATM 8266 O O    . HOH I 7 .   ? -10.443 -16.013 -10.918 1.000 16.658 0 914  HOH A O    1 ? 
HETATM 8267 O O    . HOH I 7 .   ? 2.090   -36.008 -23.222 1.000 22.478 0 915  HOH A O    1 ? 
HETATM 8268 O O    . HOH I 7 .   ? -7.426  14.749  5.574   1.000 24.199 0 916  HOH A O    1 ? 
HETATM 8269 O O    . HOH I 7 .   ? -31.434 -48.712 -13.774 1.000 20.096 0 917  HOH A O    1 ? 
HETATM 8270 O O    . HOH I 7 .   ? -8.174  -4.220  14.318  1.000 29.821 0 918  HOH A O    1 ? 
HETATM 8271 O O    . HOH I 7 .   ? -25.344 -21.582 -22.097 1.000 20.710 0 919  HOH A O    1 ? 
HETATM 8272 O O    . HOH I 7 .   ? -9.490  -4.170  4.792   1.000 12.677 0 920  HOH A O    1 ? 
HETATM 8273 O O    . HOH I 7 .   ? -28.098 -0.181  -4.553  1.000 16.294 0 921  HOH A O    1 ? 
HETATM 8274 O O    . HOH I 7 .   ? -16.831 -15.837 -29.996 1.000 18.721 0 922  HOH A O    1 ? 
HETATM 8275 O O    . HOH I 7 .   ? -13.783 -9.696  -18.957 1.000 8.638  0 923  HOH A O    1 ? 
HETATM 8276 O O    . HOH I 7 .   ? -0.533  -11.566 -10.732 1.000 20.204 0 924  HOH A O    1 ? 
HETATM 8277 O O    . HOH I 7 .   ? -32.857 -42.629 -18.977 1.000 26.185 0 925  HOH A O    1 ? 
HETATM 8278 O O    . HOH I 7 .   ? -25.533 -47.819 -34.410 1.000 26.908 0 926  HOH A O    1 ? 
HETATM 8279 O O    . HOH I 7 .   ? -6.347  14.526  -2.578  1.000 38.432 0 927  HOH A O    1 ? 
HETATM 8280 O O    . HOH I 7 .   ? -9.985  6.747   -19.593 1.000 16.205 0 928  HOH A O    1 ? 
HETATM 8281 O O    . HOH I 7 .   ? -18.094 0.524   -17.700 1.000 13.135 0 929  HOH A O    1 ? 
HETATM 8282 O O    . HOH I 7 .   ? -19.076 -11.673 -16.648 1.000 20.775 0 930  HOH A O    1 ? 
HETATM 8283 O O    . HOH I 7 .   ? -18.070 -10.131 16.502  1.000 28.366 0 931  HOH A O    1 ? 
HETATM 8284 O O    . HOH I 7 .   ? -20.593 14.127  0.419   1.000 23.633 0 932  HOH A O    1 ? 
HETATM 8285 O O    . HOH I 7 .   ? -25.356 -1.438  7.929   1.000 13.573 0 933  HOH A O    1 ? 
HETATM 8286 O O    . HOH I 7 .   ? -31.749 -3.046  2.188   1.000 30.906 0 934  HOH A O    1 ? 
HETATM 8287 O O    . HOH I 7 .   ? -15.596 -26.618 -33.464 1.000 19.989 0 935  HOH A O    1 ? 
HETATM 8288 O O    . HOH I 7 .   ? -28.197 1.977   -0.020  1.000 23.224 0 936  HOH A O    1 ? 
HETATM 8289 O O    . HOH I 7 .   ? -20.739 -17.605 4.901   1.000 31.372 0 937  HOH A O    1 ? 
HETATM 8290 O O    . HOH I 7 .   ? -20.960 -14.087 8.564   1.000 27.578 0 938  HOH A O    1 ? 
HETATM 8291 O O    . HOH I 7 .   ? -37.059 -44.072 -14.346 1.000 21.175 0 939  HOH A O    1 ? 
HETATM 8292 O O    . HOH I 7 .   ? -19.897 -37.433 -34.921 1.000 31.090 0 940  HOH A O    1 ? 
HETATM 8293 O O    . HOH I 7 .   ? -35.558 -38.080 -23.267 1.000 31.212 0 941  HOH A O    1 ? 
HETATM 8294 O O    . HOH I 7 .   ? -17.806 -8.758  -31.211 1.000 22.611 0 942  HOH A O    1 ? 
HETATM 8295 O O    . HOH I 7 .   ? 9.474   -2.366  -0.941  1.000 32.479 0 943  HOH A O    1 ? 
HETATM 8296 O O    . HOH I 7 .   ? -12.449 0.103   -21.972 1.000 16.054 0 944  HOH A O    1 ? 
HETATM 8297 O O    . HOH I 7 .   ? -31.775 -35.711 -24.635 1.000 18.589 0 945  HOH A O    1 ? 
HETATM 8298 O O    . HOH I 7 .   ? -25.432 -3.833  -19.227 1.000 33.180 0 946  HOH A O    1 ? 
HETATM 8299 O O    . HOH I 7 .   ? -15.139 11.344  -13.466 1.000 32.946 0 947  HOH A O    1 ? 
HETATM 8300 O O    . HOH I 7 .   ? -9.008  11.390  -18.433 1.000 28.272 0 948  HOH A O    1 ? 
HETATM 8301 O O    . HOH I 7 .   ? -6.777  5.318   -22.961 1.000 21.688 0 949  HOH A O    1 ? 
HETATM 8302 O O    . HOH I 7 .   ? -21.152 -13.243 -17.753 1.000 9.886  0 950  HOH A O    1 ? 
HETATM 8303 O O    . HOH I 7 .   ? -28.146 1.412   -16.499 1.000 25.220 0 951  HOH A O    1 ? 
HETATM 8304 O O    . HOH I 7 .   ? -31.633 0.263   1.681   1.000 40.182 0 952  HOH A O    1 ? 
HETATM 8305 O O    . HOH I 7 .   ? 2.276   10.236  5.853   1.000 32.100 0 953  HOH A O    1 ? 
HETATM 8306 O O    . HOH I 7 .   ? -25.541 -11.615 -2.151  1.000 16.019 0 954  HOH A O    1 ? 
HETATM 8307 O O    . HOH I 7 .   ? 7.022   10.875  1.491   1.000 35.924 0 955  HOH A O    1 ? 
HETATM 8308 O O    . HOH I 7 .   ? -25.754 -10.232 2.387   1.000 18.917 0 956  HOH A O    1 ? 
HETATM 8309 O O    . HOH I 7 .   ? -19.309 -19.313 -29.955 1.000 36.543 0 957  HOH A O    1 ? 
HETATM 8310 O O    . HOH I 7 .   ? -29.235 -10.001 -20.979 1.000 21.540 0 958  HOH A O    1 ? 
HETATM 8311 O O    . HOH I 7 .   ? 4.463   -6.859  -22.817 1.000 21.231 0 959  HOH A O    1 ? 
HETATM 8312 O O    . HOH I 7 .   ? -3.027  4.606   10.805  1.000 19.108 0 960  HOH A O    1 ? 
HETATM 8313 O O    . HOH I 7 .   ? 6.828   4.560   -16.445 1.000 29.681 0 961  HOH A O    1 ? 
HETATM 8314 O O    . HOH I 7 .   ? -24.037 0.015   -16.098 1.000 11.004 0 962  HOH A O    1 ? 
HETATM 8315 O O    . HOH I 7 .   ? -10.020 -42.884 -19.913 1.000 25.118 0 963  HOH A O    1 ? 
HETATM 8316 O O    . HOH I 7 .   ? -30.327 -8.727  -2.348  1.000 19.129 0 964  HOH A O    1 ? 
HETATM 8317 O O    . HOH I 7 .   ? 2.311   -47.669 -26.054 1.000 38.297 0 965  HOH A O    1 ? 
HETATM 8318 O O    . HOH I 7 .   ? -22.365 -15.579 4.931   1.000 32.052 0 966  HOH A O    1 ? 
HETATM 8319 O O    . HOH I 7 .   ? -17.745 -17.712 -28.306 1.000 21.103 0 967  HOH A O    1 ? 
HETATM 8320 O O    . HOH I 7 .   ? -21.932 -42.624 -12.998 1.000 21.818 0 968  HOH A O    1 ? 
HETATM 8321 O O    . HOH I 7 .   ? -17.742 11.942  11.579  1.000 19.689 0 969  HOH A O    1 ? 
HETATM 8322 O O    . HOH I 7 .   ? -7.943  -43.876 -21.611 1.000 34.703 0 970  HOH A O    1 ? 
HETATM 8323 O O    . HOH I 7 .   ? -1.530  -14.086 -11.941 1.000 22.204 0 971  HOH A O    1 ? 
HETATM 8324 O O    . HOH I 7 .   ? -21.932 -11.641 8.596   1.000 15.492 0 972  HOH A O    1 ? 
HETATM 8325 O O    . HOH I 7 .   ? -25.280 -11.786 -24.684 1.000 23.284 0 973  HOH A O    1 ? 
HETATM 8326 O O    . HOH I 7 .   ? -2.634  -4.934  5.661   1.000 15.986 0 974  HOH A O    1 ? 
HETATM 8327 O O    . HOH I 7 .   ? -22.910 0.123   14.830  1.000 18.583 0 975  HOH A O    1 ? 
HETATM 8328 O O    . HOH I 7 .   ? -12.927 -38.578 -13.704 1.000 22.648 0 976  HOH A O    1 ? 
HETATM 8329 O O    . HOH I 7 .   ? -15.957 -4.582  -29.961 1.000 17.898 0 977  HOH A O    1 ? 
HETATM 8330 O O    . HOH I 7 .   ? -28.025 4.576   0.552   1.000 18.991 0 978  HOH A O    1 ? 
HETATM 8331 O O    . HOH I 7 .   ? -6.030  -11.500 -19.433 1.000 8.158  0 979  HOH A O    1 ? 
HETATM 8332 O O    . HOH I 7 .   ? -31.964 -24.503 -19.397 1.000 27.619 0 980  HOH A O    1 ? 
HETATM 8333 O O    . HOH I 7 .   ? -18.649 -30.761 -11.736 1.000 25.280 0 981  HOH A O    1 ? 
HETATM 8334 O O    . HOH I 7 .   ? -23.025 -3.467  -22.084 1.000 31.938 0 982  HOH A O    1 ? 
HETATM 8335 O O    . HOH I 7 .   ? -20.329 -36.273 -9.732  1.000 20.824 0 983  HOH A O    1 ? 
HETATM 8336 O O    . HOH I 7 .   ? -7.008  7.106   11.364  1.000 14.853 0 984  HOH A O    1 ? 
HETATM 8337 O O    . HOH I 7 .   ? -7.080  -48.526 -27.472 1.000 23.562 0 985  HOH A O    1 ? 
HETATM 8338 O O    . HOH I 7 .   ? 11.666  2.478   -16.229 1.000 28.481 0 986  HOH A O    1 ? 
HETATM 8339 O O    . HOH I 7 .   ? 10.345  13.531  -6.545  1.000 21.639 0 987  HOH A O    1 ? 
HETATM 8340 O O    . HOH I 7 .   ? -35.356 -36.025 -16.491 1.000 26.602 0 988  HOH A O    1 ? 
HETATM 8341 O O    . HOH I 7 .   ? 2.075   -25.478 -29.768 1.000 30.894 0 989  HOH A O    1 ? 
HETATM 8342 O O    . HOH I 7 .   ? -20.448 -2.187  15.524  1.000 16.518 0 990  HOH A O    1 ? 
HETATM 8343 O O    . HOH I 7 .   ? -10.188 -15.256 3.767   1.000 42.538 0 991  HOH A O    1 ? 
HETATM 8344 O O    . HOH I 7 .   ? -29.264 -23.571 -15.329 1.000 21.949 0 992  HOH A O    1 ? 
HETATM 8345 O O    . HOH I 7 .   ? -12.641 -11.437 13.930  1.000 32.460 0 993  HOH A O    1 ? 
HETATM 8346 O O    . HOH I 7 .   ? -12.047 -3.188  0.560   1.000 12.072 0 994  HOH A O    1 ? 
HETATM 8347 O O    . HOH I 7 .   ? -5.864  18.504  -12.097 1.000 36.728 0 995  HOH A O    1 ? 
HETATM 8348 O O    . HOH I 7 .   ? 3.204   -15.660 -29.598 1.000 25.587 0 996  HOH A O    1 ? 
HETATM 8349 O O    . HOH I 7 .   ? 8.616   -0.374  -23.248 1.000 23.163 0 997  HOH A O    1 ? 
HETATM 8350 O O    . HOH I 7 .   ? 6.467   19.942  -5.833  1.000 32.003 0 998  HOH A O    1 ? 
HETATM 8351 O O    . HOH I 7 .   ? -31.752 -2.355  -6.047  1.000 17.666 0 999  HOH A O    1 ? 
HETATM 8352 O O    . HOH I 7 .   ? -22.341 -12.786 -31.422 1.000 42.704 0 1000 HOH A O    1 ? 
HETATM 8353 O O    . HOH I 7 .   ? 13.409  -6.863  -14.416 1.000 30.534 0 1001 HOH A O    1 ? 
HETATM 8354 O O    . HOH I 7 .   ? -7.894  -33.606 -12.891 1.000 21.223 0 1002 HOH A O    1 ? 
HETATM 8355 O O    . HOH I 7 .   ? -11.641 -35.971 -12.709 1.000 22.387 0 1003 HOH A O    1 ? 
HETATM 8356 O O    . HOH I 7 .   ? -33.438 -16.884 -15.138 1.000 39.597 0 1004 HOH A O    1 ? 
HETATM 8357 O O    . HOH I 7 .   ? -2.567  -37.456 -37.480 1.000 18.102 0 1005 HOH A O    1 ? 
HETATM 8358 O O    . HOH I 7 .   ? 2.433   3.202   3.408   1.000 22.488 0 1006 HOH A O    1 ? 
HETATM 8359 O O    . HOH I 7 .   ? -19.254 -25.282 -36.334 1.000 36.061 0 1007 HOH A O    1 ? 
HETATM 8360 O O    . HOH I 7 .   ? 8.599   5.269   -1.239  1.000 24.514 0 1008 HOH A O    1 ? 
HETATM 8361 O O    . HOH I 7 .   ? -9.857  -13.530 5.623   1.000 30.803 0 1009 HOH A O    1 ? 
HETATM 8362 O O    . HOH I 7 .   ? 6.229   -9.047  -13.073 1.000 21.874 0 1010 HOH A O    1 ? 
HETATM 8363 O O    . HOH I 7 .   ? -18.515 5.290   -17.347 1.000 27.135 0 1011 HOH A O    1 ? 
HETATM 8364 O O    . HOH I 7 .   ? -32.032 -36.397 -28.315 1.000 37.127 0 1012 HOH A O    1 ? 
HETATM 8365 O O    . HOH I 7 .   ? -14.801 -20.565 -34.890 1.000 38.177 0 1013 HOH A O    1 ? 
HETATM 8366 O O    . HOH I 7 .   ? -29.007 -5.203  -3.587  1.000 13.767 0 1014 HOH A O    1 ? 
HETATM 8367 O O    . HOH I 7 .   ? 6.529   -12.174 -10.652 1.000 24.814 0 1015 HOH A O    1 ? 
HETATM 8368 O O    . HOH I 7 .   ? -31.215 -16.666 -13.537 1.000 16.680 0 1016 HOH A O    1 ? 
HETATM 8369 O O    . HOH I 7 .   ? -21.287 -26.784 -30.379 1.000 25.239 0 1017 HOH A O    1 ? 
HETATM 8370 O O    . HOH I 7 .   ? -31.157 -17.157 -1.961  1.000 36.984 0 1018 HOH A O    1 ? 
HETATM 8371 O O    . HOH I 7 .   ? 12.634  -0.401  -12.050 1.000 30.780 0 1019 HOH A O    1 ? 
HETATM 8372 O O    . HOH I 7 .   ? -4.795  -0.003  -3.493  1.000 11.471 0 1020 HOH A O    1 ? 
HETATM 8373 O O    . HOH I 7 .   ? 14.756  -9.675  -19.711 1.000 47.937 0 1021 HOH A O    1 ? 
HETATM 8374 O O    . HOH I 7 .   ? 6.105   2.812   -14.358 1.000 26.989 0 1022 HOH A O    1 ? 
HETATM 8375 O O    . HOH I 7 .   ? -1.375  15.446  4.624   1.000 33.859 0 1023 HOH A O    1 ? 
HETATM 8376 O O    . HOH I 7 .   ? 3.556   21.348  -15.364 1.000 33.611 0 1024 HOH A O    1 ? 
HETATM 8377 O O    . HOH I 7 .   ? -5.777  -11.405 -11.667 1.000 18.604 0 1025 HOH A O    1 ? 
HETATM 8378 O O    . HOH I 7 .   ? -0.893  -10.306 -5.641  1.000 21.383 0 1026 HOH A O    1 ? 
HETATM 8379 O O    . HOH I 7 .   ? -14.623 -44.072 -24.115 1.000 25.199 0 1027 HOH A O    1 ? 
HETATM 8380 O O    . HOH I 7 .   ? -22.189 14.984  11.243  1.000 44.098 0 1028 HOH A O    1 ? 
HETATM 8381 O O    . HOH I 7 .   ? -14.282 -7.364  -17.493 1.000 8.999  0 1029 HOH A O    1 ? 
HETATM 8382 O O    . HOH I 7 .   ? -16.395 -9.423  20.204  1.000 31.867 0 1030 HOH A O    1 ? 
HETATM 8383 O O    . HOH I 7 .   ? -15.637 9.520   -18.004 1.000 44.604 0 1031 HOH A O    1 ? 
HETATM 8384 O O    . HOH I 7 .   ? -28.881 -33.091 -10.216 1.000 26.060 0 1032 HOH A O    1 ? 
HETATM 8385 O O    . HOH I 7 .   ? 9.029   -50.988 -24.579 1.000 33.527 0 1033 HOH A O    1 ? 
HETATM 8386 O O    . HOH I 7 .   ? -24.018 4.308   15.136  1.000 22.407 0 1034 HOH A O    1 ? 
HETATM 8387 O O    . HOH I 7 .   ? 6.387   -40.797 -29.687 1.000 25.748 0 1035 HOH A O    1 ? 
HETATM 8388 O O    . HOH I 7 .   ? -29.292 -21.196 -7.934  1.000 32.048 0 1036 HOH A O    1 ? 
HETATM 8389 O O    . HOH I 7 .   ? -4.403  14.513  -24.618 1.000 27.244 0 1037 HOH A O    1 ? 
HETATM 8390 O O    . HOH I 7 .   ? 13.266  3.107   -6.660  1.000 41.933 0 1038 HOH A O    1 ? 
HETATM 8391 O O    . HOH I 7 .   ? -12.746 -46.056 -24.820 1.000 29.991 0 1039 HOH A O    1 ? 
HETATM 8392 O O    . HOH I 7 .   ? -24.411 -5.158  -21.583 1.000 29.567 0 1040 HOH A O    1 ? 
HETATM 8393 O O    . HOH I 7 .   ? -10.142 -40.647 -37.271 1.000 32.917 0 1041 HOH A O    1 ? 
HETATM 8394 O O    . HOH I 7 .   ? 4.768   18.267  -6.165  1.000 30.090 0 1042 HOH A O    1 ? 
HETATM 8395 O O    . HOH I 7 .   ? -14.983 12.866  13.475  1.000 19.652 0 1043 HOH A O    1 ? 
HETATM 8396 O O    . HOH I 7 .   ? -5.488  -7.047  5.886   1.000 26.304 0 1044 HOH A O    1 ? 
HETATM 8397 O O    . HOH I 7 .   ? -23.865 -23.361 -29.828 1.000 34.692 0 1045 HOH A O    1 ? 
HETATM 8398 O O    . HOH I 7 .   ? -26.529 -34.245 -38.688 1.000 31.875 0 1046 HOH A O    1 ? 
HETATM 8399 O O    . HOH I 7 .   ? -5.829  -14.829 2.983   1.000 33.387 0 1047 HOH A O    1 ? 
HETATM 8400 O O    . HOH I 7 .   ? 3.389   -1.622  8.447   1.000 24.264 0 1048 HOH A O    1 ? 
HETATM 8401 O O    . HOH I 7 .   ? 3.803   -14.056 -2.012  1.000 42.808 0 1049 HOH A O    1 ? 
HETATM 8402 O O    . HOH I 7 .   ? -7.219  -40.416 -35.452 1.000 23.367 0 1050 HOH A O    1 ? 
HETATM 8403 O O    . HOH I 7 .   ? -20.567 -16.399 -28.256 1.000 25.067 0 1051 HOH A O    1 ? 
HETATM 8404 O O    . HOH I 7 .   ? -16.491 20.764  -3.758  1.000 46.656 0 1052 HOH A O    1 ? 
HETATM 8405 O O    . HOH I 7 .   ? 8.355   22.354  -13.509 1.000 34.953 0 1053 HOH A O    1 ? 
HETATM 8406 O O    . HOH I 7 .   ? -18.984 -11.603 14.585  1.000 25.260 0 1054 HOH A O    1 ? 
HETATM 8407 O O    . HOH I 7 .   ? -11.645 -2.353  -2.130  1.000 10.777 0 1055 HOH A O    1 ? 
HETATM 8408 O O    . HOH I 7 .   ? -13.107 22.765  1.541   1.000 33.884 0 1056 HOH A O    1 ? 
HETATM 8409 O O    . HOH I 7 .   ? -22.223 18.095  0.757   1.000 34.449 0 1057 HOH A O    1 ? 
HETATM 8410 O O    . HOH I 7 .   ? -28.044 -6.637  12.599  1.000 29.819 0 1058 HOH A O    1 ? 
HETATM 8411 O O    . HOH I 7 .   ? -13.578 8.350   16.675  1.000 41.006 0 1059 HOH A O    1 ? 
HETATM 8412 O O    . HOH I 7 .   ? -13.667 4.178   -20.610 1.000 38.518 0 1060 HOH A O    1 ? 
HETATM 8413 O O    . HOH I 7 .   ? 3.297   -16.875 -12.046 1.000 42.197 0 1061 HOH A O    1 ? 
HETATM 8414 O O    . HOH I 7 .   ? -27.728 0.092   5.958   1.000 14.562 0 1062 HOH A O    1 ? 
HETATM 8415 O O    . HOH I 7 .   ? 5.029   14.945  -16.620 1.000 18.887 0 1063 HOH A O    1 ? 
HETATM 8416 O O    . HOH I 7 .   ? -19.647 -36.765 -39.518 1.000 29.298 0 1064 HOH A O    1 ? 
HETATM 8417 O O    . HOH I 7 .   ? -21.350 -43.780 -18.537 1.000 21.396 0 1065 HOH A O    1 ? 
HETATM 8418 O O    . HOH I 7 .   ? -23.969 8.858   4.341   1.000 30.640 0 1066 HOH A O    1 ? 
HETATM 8419 O O    . HOH I 7 .   ? 1.417   -33.453 -26.328 1.000 31.232 0 1067 HOH A O    1 ? 
HETATM 8420 O O    . HOH I 7 .   ? -22.508 -40.639 -9.349  1.000 23.763 0 1068 HOH A O    1 ? 
HETATM 8421 O O    . HOH I 7 .   ? -8.604  -9.469  -1.066  1.000 11.791 0 1069 HOH A O    1 ? 
HETATM 8422 O O    . HOH I 7 .   ? 10.833  7.659   -19.995 1.000 23.530 0 1070 HOH A O    1 ? 
HETATM 8423 O O    . HOH I 7 .   ? -24.124 -3.786  8.883   1.000 14.240 0 1071 HOH A O    1 ? 
HETATM 8424 O O    . HOH I 7 .   ? 5.767   -16.940 -24.430 1.000 29.086 0 1072 HOH A O    1 ? 
HETATM 8425 O O    . HOH I 7 .   ? -11.369 -13.111 -32.487 1.000 39.826 0 1073 HOH A O    1 ? 
HETATM 8426 O O    . HOH I 7 .   ? -24.261 13.456  8.379   1.000 31.778 0 1074 HOH A O    1 ? 
HETATM 8427 O O    . HOH I 7 .   ? -32.781 -2.957  -12.985 1.000 20.355 0 1075 HOH A O    1 ? 
HETATM 8428 O O    . HOH I 7 .   ? -30.917 -3.041  11.770  1.000 33.519 0 1076 HOH A O    1 ? 
HETATM 8429 O O    . HOH I 7 .   ? -19.411 -44.840 -25.560 1.000 21.945 0 1077 HOH A O    1 ? 
HETATM 8430 O O    . HOH I 7 .   ? -9.055  -13.196 -11.688 1.000 25.363 0 1078 HOH A O    1 ? 
HETATM 8431 O O    . HOH I 7 .   ? -11.607 5.312   -21.207 1.000 26.728 0 1079 HOH A O    1 ? 
HETATM 8432 O O    . HOH I 7 .   ? -20.201 3.595   -21.453 1.000 28.761 0 1080 HOH A O    1 ? 
HETATM 8433 O O    . HOH I 7 .   ? -24.325 -28.012 -30.634 1.000 28.385 0 1081 HOH A O    1 ? 
HETATM 8434 O O    . HOH I 7 .   ? -29.737 -39.305 -29.510 1.000 23.854 0 1082 HOH A O    1 ? 
HETATM 8435 O O    . HOH I 7 .   ? -10.042 -47.360 -34.694 1.000 20.747 0 1083 HOH A O    1 ? 
HETATM 8436 O O    . HOH I 7 .   ? 2.533   -16.073 -14.628 1.000 33.508 0 1084 HOH A O    1 ? 
HETATM 8437 O O    . HOH I 7 .   ? 5.940   -9.971  -15.587 1.000 29.747 0 1085 HOH A O    1 ? 
HETATM 8438 O O    . HOH I 7 .   ? -13.157 -9.906  -8.528  1.000 24.247 0 1086 HOH A O    1 ? 
HETATM 8439 O O    . HOH I 7 .   ? -16.513 -45.574 -25.863 1.000 27.875 0 1087 HOH A O    1 ? 
HETATM 8440 O O    . HOH I 7 .   ? -5.113  -46.182 -24.062 1.000 40.298 0 1088 HOH A O    1 ? 
HETATM 8441 O O    . HOH I 7 .   ? -27.790 -0.826  -18.195 1.000 36.546 0 1089 HOH A O    1 ? 
HETATM 8442 O O    . HOH I 7 .   ? 8.703   -7.307  6.017   1.000 35.001 0 1090 HOH A O    1 ? 
HETATM 8443 O O    . HOH I 7 .   ? -18.417 1.382   15.581  1.000 20.990 0 1091 HOH A O    1 ? 
HETATM 8444 O O    . HOH I 7 .   ? -18.420 -49.288 -33.892 1.000 42.035 0 1092 HOH A O    1 ? 
HETATM 8445 O O    . HOH I 7 .   ? -27.110 -8.928  4.550   1.000 33.638 0 1093 HOH A O    1 ? 
HETATM 8446 O O    . HOH I 7 .   ? -12.437 -9.455  -4.831  1.000 25.756 0 1094 HOH A O    1 ? 
HETATM 8447 O O    . HOH I 7 .   ? 11.570  0.333   -17.699 1.000 42.784 0 1095 HOH A O    1 ? 
HETATM 8448 O O    . HOH I 7 .   ? -16.725 21.743  -0.993  1.000 23.384 0 1096 HOH A O    1 ? 
HETATM 8449 O O    . HOH I 7 .   ? -10.123 -14.612 -0.179  1.000 31.073 0 1097 HOH A O    1 ? 
HETATM 8450 O O    . HOH I 7 .   ? -12.277 9.790   -16.202 1.000 18.506 0 1098 HOH A O    1 ? 
HETATM 8451 O O    . HOH I 7 .   ? -31.442 -15.472 -7.864  1.000 26.204 0 1099 HOH A O    1 ? 
HETATM 8452 O O    . HOH I 7 .   ? -17.412 -18.205 -0.406  1.000 41.836 0 1100 HOH A O    1 ? 
HETATM 8453 O O    . HOH I 7 .   ? -9.940  -48.715 -26.559 1.000 30.903 0 1101 HOH A O    1 ? 
HETATM 8454 O O    . HOH I 7 .   ? -30.475 -18.141 -9.552  1.000 30.994 0 1102 HOH A O    1 ? 
HETATM 8455 O O    . HOH I 7 .   ? -27.873 -43.276 -24.720 1.000 22.101 0 1103 HOH A O    1 ? 
HETATM 8456 O O    . HOH I 7 .   ? -11.103 21.965  2.620   1.000 40.684 0 1104 HOH A O    1 ? 
HETATM 8457 O O    . HOH I 7 .   ? 10.668  5.761   -2.931  1.000 27.796 0 1105 HOH A O    1 ? 
HETATM 8458 O O    . HOH I 7 .   ? -1.050  -10.213 -35.050 1.000 49.257 0 1106 HOH A O    1 ? 
HETATM 8459 O O    . HOH I 7 .   ? 2.865   -23.756 -19.755 1.000 42.847 0 1107 HOH A O    1 ? 
HETATM 8460 O O    . HOH I 7 .   ? 12.611  5.997   -7.294  1.000 32.959 0 1108 HOH A O    1 ? 
HETATM 8461 O O    . HOH I 7 .   ? -15.901 -30.890 -9.900  1.000 39.682 0 1109 HOH A O    1 ? 
HETATM 8462 O O    . HOH I 7 .   ? 2.015   -13.125 -32.571 1.000 34.553 0 1110 HOH A O    1 ? 
HETATM 8463 O O    . HOH I 7 .   ? -5.011  15.320  3.545   1.000 35.916 0 1111 HOH A O    1 ? 
HETATM 8464 O O    . HOH I 7 .   ? -27.948 -19.675 -4.093  1.000 36.473 0 1112 HOH A O    1 ? 
HETATM 8465 O O    . HOH I 7 .   ? -11.017 -25.727 7.576   1.000 40.783 0 1113 HOH A O    1 ? 
HETATM 8466 O O    . HOH I 7 .   ? 9.116   -47.859 -25.577 1.000 37.647 0 1114 HOH A O    1 ? 
HETATM 8467 O O    . HOH I 7 .   ? 3.371   3.100   10.447  1.000 38.913 0 1115 HOH A O    1 ? 
HETATM 8468 O O    . HOH I 7 .   ? -14.575 16.528  -8.401  1.000 34.295 0 1116 HOH A O    1 ? 
HETATM 8469 O O    . HOH I 7 .   ? -12.861 -2.851  -29.509 1.000 34.194 0 1117 HOH A O    1 ? 
HETATM 8470 O O    . HOH I 7 .   ? -15.278 -38.366 -12.663 1.000 36.451 0 1118 HOH A O    1 ? 
HETATM 8471 O O    . HOH I 7 .   ? -31.071 8.218   1.080   1.000 47.194 0 1119 HOH A O    1 ? 
HETATM 8472 O O    . HOH I 7 .   ? -23.805 -48.300 -30.242 1.000 40.574 0 1120 HOH A O    1 ? 
HETATM 8473 O O    . HOH I 7 .   ? -1.040  -26.222 -10.738 1.000 24.868 0 1121 HOH A O    1 ? 
HETATM 8474 O O    . HOH I 7 .   ? -16.907 18.306  -8.375  1.000 44.832 0 1122 HOH A O    1 ? 
HETATM 8475 O O    . HOH I 7 .   ? -32.468 -33.316 -25.547 1.000 38.217 0 1123 HOH A O    1 ? 
HETATM 8476 O O    . HOH I 7 .   ? -17.860 -21.838 -6.481  1.000 44.308 0 1124 HOH A O    1 ? 
HETATM 8477 O O    . HOH I 7 .   ? -18.611 -49.239 -25.364 1.000 46.300 0 1125 HOH A O    1 ? 
HETATM 8478 O O    . HOH I 7 .   ? -15.704 -22.592 -33.176 1.000 36.378 0 1126 HOH A O    1 ? 
HETATM 8479 O O    . HOH I 7 .   ? -12.810 -10.632 -33.057 1.000 30.771 0 1127 HOH A O    1 ? 
HETATM 8480 O O    . HOH I 7 .   ? -29.027 -50.346 -13.814 1.000 30.851 0 1128 HOH A O    1 ? 
HETATM 8481 O O    . HOH I 7 .   ? -28.327 -4.273  7.802   1.000 27.096 0 1129 HOH A O    1 ? 
HETATM 8482 O O    . HOH I 7 .   ? 11.873  0.801   -7.293  1.000 31.914 0 1130 HOH A O    1 ? 
HETATM 8483 O O    . HOH I 7 .   ? -9.993  -37.576 -40.784 1.000 38.743 0 1131 HOH A O    1 ? 
HETATM 8484 O O    . HOH I 7 .   ? -1.501  14.057  -29.387 1.000 33.132 0 1132 HOH A O    1 ? 
HETATM 8485 O O    . HOH I 7 .   ? -33.413 -38.165 -24.807 1.000 32.393 0 1133 HOH A O    1 ? 
HETATM 8486 O O    . HOH I 7 .   ? -28.988 1.548   9.929   1.000 37.286 0 1134 HOH A O    1 ? 
HETATM 8487 O O    . HOH I 7 .   ? 3.886   -22.338 -11.268 1.000 35.883 0 1135 HOH A O    1 ? 
HETATM 8488 O O    . HOH I 7 .   ? -27.461 5.212   -9.193  1.000 33.195 0 1136 HOH A O    1 ? 
HETATM 8489 O O    . HOH I 7 .   ? -19.686 -12.831 -5.626  1.000 22.807 0 1137 HOH A O    1 ? 
HETATM 8490 O O    . HOH I 7 .   ? -27.718 10.967  5.202   1.000 44.211 0 1138 HOH A O    1 ? 
HETATM 8491 O O    . HOH I 7 .   ? -31.064 -8.041  -21.239 1.000 36.772 0 1139 HOH A O    1 ? 
HETATM 8492 O O    . HOH I 7 .   ? 2.110   -29.516 -22.805 1.000 41.130 0 1140 HOH A O    1 ? 
HETATM 8493 O O    . HOH I 7 .   ? -5.612  15.714  -18.640 1.000 40.533 0 1141 HOH A O    1 ? 
HETATM 8494 O O    . HOH I 7 .   ? -19.010 -44.508 -19.878 1.000 35.416 0 1142 HOH A O    1 ? 
HETATM 8495 O O    . HOH I 7 .   ? 5.006   -25.387 -29.261 1.000 51.222 0 1143 HOH A O    1 ? 
HETATM 8496 O O    . HOH I 7 .   ? -2.324  -46.267 -24.761 1.000 39.154 0 1144 HOH A O    1 ? 
HETATM 8497 O O    . HOH I 7 .   ? -11.104 14.107  -6.596  1.000 33.711 0 1145 HOH A O    1 ? 
HETATM 8498 O O    . HOH I 7 .   ? -12.049 -16.726 11.701  1.000 41.812 0 1146 HOH A O    1 ? 
HETATM 8499 O O    . HOH I 7 .   ? -15.057 9.546   -15.386 1.000 33.016 0 1147 HOH A O    1 ? 
HETATM 8500 O O    . HOH I 7 .   ? 9.987   4.089   -17.256 1.000 30.887 0 1148 HOH A O    1 ? 
HETATM 8501 O O    . HOH I 7 .   ? 6.413   -44.639 -26.934 1.000 48.415 0 1149 HOH A O    1 ? 
HETATM 8502 O O    . HOH I 7 .   ? -27.457 -33.333 -14.185 1.000 27.723 0 1150 HOH A O    1 ? 
HETATM 8503 O O    . HOH I 7 .   ? 7.579   -11.074 -27.569 1.000 33.412 0 1151 HOH A O    1 ? 
HETATM 8504 O O    . HOH I 7 .   ? -18.631 -44.042 -13.122 1.000 38.829 0 1152 HOH A O    1 ? 
HETATM 8505 O O    . HOH I 7 .   ? -32.569 -8.609  -0.751  1.000 37.307 0 1153 HOH A O    1 ? 
HETATM 8506 O O    . HOH I 7 .   ? -11.310 9.108   -18.947 1.000 22.541 0 1154 HOH A O    1 ? 
HETATM 8507 O O    . HOH I 7 .   ? 4.664   -7.373  -16.134 1.000 31.441 0 1155 HOH A O    1 ? 
HETATM 8508 O O    . HOH I 7 .   ? 11.251  -8.807  -19.158 1.000 44.622 0 1156 HOH A O    1 ? 
HETATM 8509 O O    . HOH I 7 .   ? -22.293 -38.021 -40.792 1.000 41.769 0 1157 HOH A O    1 ? 
HETATM 8510 O O    . HOH I 7 .   ? -7.523  13.642  -18.968 1.000 39.350 0 1158 HOH A O    1 ? 
HETATM 8511 O O    . HOH I 7 .   ? -15.920 4.370   -20.121 1.000 30.339 0 1159 HOH A O    1 ? 
HETATM 8512 O O    . HOH I 7 .   ? -8.521  10.541  14.548  1.000 40.830 0 1160 HOH A O    1 ? 
HETATM 8513 O O    . HOH I 7 .   ? 9.495   -4.035  6.284   1.000 37.639 0 1161 HOH A O    1 ? 
HETATM 8514 O O    . HOH I 7 .   ? -25.728 -8.077  6.866   1.000 20.895 0 1162 HOH A O    1 ? 
HETATM 8515 O O    . HOH I 7 .   ? -21.456 -14.533 -4.721  1.000 33.980 0 1163 HOH A O    1 ? 
HETATM 8516 O O    . HOH I 7 .   ? -24.827 11.512  13.070  1.000 29.318 0 1164 HOH A O    1 ? 
HETATM 8517 O O    . HOH I 7 .   ? -27.610 -49.849 -27.758 1.000 51.056 0 1165 HOH A O    1 ? 
HETATM 8518 O O    . HOH I 7 .   ? -3.409  -9.770  -10.713 1.000 20.536 0 1166 HOH A O    1 ? 
HETATM 8519 O O    . HOH I 7 .   ? -27.637 -8.811  -22.979 1.000 26.600 0 1167 HOH A O    1 ? 
HETATM 8520 O O    . HOH I 7 .   ? -31.478 -21.695 -14.420 1.000 39.195 0 1168 HOH A O    1 ? 
HETATM 8521 O O    . HOH I 7 .   ? -21.640 8.564   18.539  1.000 50.988 0 1169 HOH A O    1 ? 
HETATM 8522 O O    . HOH I 7 .   ? -19.087 -38.251 -37.710 1.000 37.357 0 1170 HOH A O    1 ? 
HETATM 8523 O O    . HOH I 7 .   ? 5.024   -9.617  -22.618 1.000 34.213 0 1171 HOH A O    1 ? 
HETATM 8524 O O    . HOH I 7 .   ? -28.044 -45.621 -18.618 1.000 36.056 0 1172 HOH A O    1 ? 
HETATM 8525 O O    . HOH I 7 .   ? -21.503 -48.631 -34.968 1.000 44.099 0 1173 HOH A O    1 ? 
HETATM 8526 O O    . HOH I 7 .   ? 13.529  8.406   -9.032  1.000 45.049 0 1174 HOH A O    1 ? 
HETATM 8527 O O    . HOH I 7 .   ? -7.021  -22.336 -10.397 1.000 33.849 0 1175 HOH A O    1 ? 
HETATM 8528 O O    . HOH I 7 .   ? 0.372   -23.636 -36.772 1.000 36.415 0 1176 HOH A O    1 ? 
HETATM 8529 O O    . HOH I 7 .   ? -7.815  -11.887 -10.244 1.000 40.222 0 1177 HOH A O    1 ? 
HETATM 8530 O O    . HOH I 7 .   ? -9.593  16.575  5.786   1.000 39.885 0 1178 HOH A O    1 ? 
HETATM 8531 O O    . HOH I 7 .   ? -3.440  -11.546 -5.371  1.000 43.130 0 1179 HOH A O    1 ? 
HETATM 8532 O O    . HOH I 7 .   ? 1.592   -28.523 -30.062 1.000 32.750 0 1180 HOH A O    1 ? 
HETATM 8533 O O    . HOH I 7 .   ? -20.765 0.419   16.668  1.000 29.401 0 1181 HOH A O    1 ? 
HETATM 8534 O O    . HOH I 7 .   ? -32.313 -33.675 -28.218 1.000 42.662 0 1182 HOH A O    1 ? 
HETATM 8535 O O    . HOH I 7 .   ? -29.586 1.705   7.282   1.000 35.370 0 1183 HOH A O    1 ? 
HETATM 8536 O O    . HOH I 7 .   ? -18.329 4.589   -28.401 1.000 40.975 0 1184 HOH A O    1 ? 
HETATM 8537 O O    . HOH I 7 .   ? -19.066 -47.232 -35.941 1.000 49.113 0 1185 HOH A O    1 ? 
HETATM 8538 O O    . HOH I 7 .   ? 5.081   17.299  1.659   1.000 37.159 0 1186 HOH A O    1 ? 
HETATM 8539 O O    . HOH I 7 .   ? -6.254  -4.658  16.106  1.000 30.835 0 1187 HOH A O    1 ? 
HETATM 8540 O O    . HOH I 7 .   ? -27.960 -49.039 -16.595 1.000 49.488 0 1188 HOH A O    1 ? 
HETATM 8541 O O    . HOH I 7 .   ? -23.933 -43.057 -19.456 1.000 35.683 0 1189 HOH A O    1 ? 
HETATM 8542 O O    . HOH I 7 .   ? -6.035  -9.888  6.728   1.000 35.188 0 1190 HOH A O    1 ? 
HETATM 8543 O O    . HOH I 7 .   ? -18.159 14.617  11.177  1.000 26.472 0 1191 HOH A O    1 ? 
HETATM 8544 O O    . HOH I 7 .   ? -0.547  12.729  8.328   1.000 27.097 0 1192 HOH A O    1 ? 
HETATM 8545 O O    . HOH I 7 .   ? -6.447  14.619  9.875   1.000 25.821 0 1193 HOH A O    1 ? 
HETATM 8546 O O    . HOH I 7 .   ? -16.344 -36.732 -40.601 1.000 44.077 0 1194 HOH A O    1 ? 
HETATM 8547 O O    . HOH I 7 .   ? -0.773  20.171  -1.138  1.000 43.257 0 1195 HOH A O    1 ? 
HETATM 8548 O O    . HOH I 7 .   ? -15.803 -43.863 -17.044 1.000 39.114 0 1196 HOH A O    1 ? 
HETATM 8549 O O    . HOH I 7 .   ? -25.831 12.082  -3.984  1.000 34.460 0 1197 HOH A O    1 ? 
HETATM 8550 O O    . HOH I 7 .   ? 5.419   -11.013 -31.284 1.000 26.693 0 1198 HOH A O    1 ? 
HETATM 8551 O O    . HOH I 7 .   ? -23.430 -44.698 -13.780 1.000 41.236 0 1199 HOH A O    1 ? 
HETATM 8552 O O    . HOH I 7 .   ? -25.239 -19.499 -23.693 1.000 27.005 0 1200 HOH A O    1 ? 
HETATM 8553 O O    . HOH I 7 .   ? -17.842 -19.615 2.114   1.000 47.650 0 1201 HOH A O    1 ? 
HETATM 8554 O O    . HOH I 7 .   ? -30.024 -42.319 -27.334 1.000 43.183 0 1202 HOH A O    1 ? 
HETATM 8555 O O    . HOH I 7 .   ? -0.287  16.788  1.582   1.000 48.567 0 1203 HOH A O    1 ? 
HETATM 8556 O O    . HOH I 7 .   ? 5.263   21.571  -7.917  1.000 36.618 0 1204 HOH A O    1 ? 
HETATM 8557 O O    . HOH I 7 .   ? -20.473 12.045  15.377  1.000 41.820 0 1205 HOH A O    1 ? 
HETATM 8558 O O    . HOH I 7 .   ? -28.618 9.346   7.443   1.000 50.858 0 1206 HOH A O    1 ? 
HETATM 8559 O O    . HOH I 7 .   ? -30.032 -5.222  13.169  1.000 26.947 0 1207 HOH A O    1 ? 
HETATM 8560 O O    . HOH I 7 .   ? -24.098 -11.500 10.361  1.000 16.458 0 1208 HOH A O    1 ? 
HETATM 8561 O O    . HOH I 7 .   ? -33.474 -28.750 -19.538 1.000 33.896 0 1209 HOH A O    1 ? 
HETATM 8562 O O    . HOH I 7 .   ? -23.527 14.549  0.216   1.000 31.060 0 1210 HOH A O    1 ? 
HETATM 8563 O O    . HOH I 7 .   ? 4.940   11.367  5.062   1.000 38.866 0 1211 HOH A O    1 ? 
HETATM 8564 O O    . HOH I 7 .   ? -12.427 -44.153 -19.989 1.000 34.321 0 1212 HOH A O    1 ? 
HETATM 8565 O O    . HOH I 7 .   ? -18.119 -33.669 -45.537 1.000 48.505 0 1213 HOH A O    1 ? 
HETATM 8566 O O    . HOH I 7 .   ? 10.723  6.337   -17.659 1.000 26.301 0 1214 HOH A O    1 ? 
HETATM 8567 O O    . HOH I 7 .   ? 0.255   -16.134 -13.593 1.000 39.034 0 1215 HOH A O    1 ? 
HETATM 8568 O O    . HOH I 7 .   ? -24.501 10.670  -10.645 1.000 37.031 0 1216 HOH A O    1 ? 
HETATM 8569 O O    . HOH I 7 .   ? -7.260  -12.702 -2.786  1.000 37.324 0 1217 HOH A O    1 ? 
HETATM 8570 O O    . HOH I 7 .   ? -11.558 0.153   -24.625 1.000 39.794 0 1218 HOH A O    1 ? 
HETATM 8571 O O    . HOH I 7 .   ? 0.204   -14.508 -35.235 1.000 43.131 0 1219 HOH A O    1 ? 
HETATM 8572 O O    . HOH I 7 .   ? 2.396   -41.693 -20.974 1.000 39.885 0 1220 HOH A O    1 ? 
HETATM 8573 O O    . HOH I 7 .   ? -0.290  15.047  7.398   1.000 38.359 0 1221 HOH A O    1 ? 
HETATM 8574 O O    . HOH I 7 .   ? -23.504 3.233   -22.510 1.000 42.108 0 1222 HOH A O    1 ? 
HETATM 8575 O O    . HOH I 7 .   ? -28.186 -11.389 3.829   1.000 36.872 0 1223 HOH A O    1 ? 
HETATM 8576 O O    . HOH I 7 .   ? -27.773 6.301   -1.804  1.000 29.267 0 1224 HOH A O    1 ? 
HETATM 8577 O O    . HOH I 7 .   ? 8.311   7.615   -0.123  1.000 44.194 0 1225 HOH A O    1 ? 
HETATM 8578 O O    . HOH I 7 .   ? 3.989   -21.374 -20.039 1.000 54.444 0 1226 HOH A O    1 ? 
HETATM 8579 O O    . HOH I 7 .   ? -33.309 0.868   15.204  1.000 45.612 0 1227 HOH A O    1 ? 
HETATM 8580 O O    . HOH I 7 .   ? -23.544 -16.521 -25.103 1.000 30.814 0 1228 HOH A O    1 ? 
HETATM 8581 O O    . HOH I 7 .   ? -7.340  -10.433 -6.212  1.000 43.046 0 1229 HOH A O    1 ? 
HETATM 8582 O O    . HOH I 7 .   ? -20.501 -17.714 -6.592  1.000 37.553 0 1230 HOH A O    1 ? 
HETATM 8583 O O    . HOH I 7 .   ? -6.508  11.603  -21.316 1.000 36.624 0 1231 HOH A O    1 ? 
HETATM 8584 O O    . HOH I 7 .   ? -5.678  19.703  -2.867  1.000 44.772 0 1232 HOH A O    1 ? 
HETATM 8585 O O    . HOH I 7 .   ? -29.203 -31.762 -18.492 1.000 12.787 0 1233 HOH A O    1 ? 
HETATM 8586 O O    . HOH I 7 .   ? 0.507   -15.572 -8.829  1.000 38.845 0 1234 HOH A O    1 ? 
HETATM 8587 O O    . HOH I 7 .   ? -11.899 -17.207 -7.366  1.000 38.196 0 1235 HOH A O    1 ? 
HETATM 8588 O O    . HOH I 7 .   ? -10.463 13.488  -17.422 1.000 42.412 0 1236 HOH A O    1 ? 
HETATM 8589 O O    . HOH I 7 .   ? -27.695 -10.788 -24.818 1.000 38.272 0 1237 HOH A O    1 ? 
HETATM 8590 O O    . HOH I 7 .   ? -12.020 15.696  10.533  1.000 38.922 0 1238 HOH A O    1 ? 
HETATM 8591 O O    . HOH I 7 .   ? -3.332  -26.400 -10.277 1.000 42.819 0 1239 HOH A O    1 ? 
HETATM 8592 O O    . HOH I 7 .   ? -40.529 -8.245  -9.472  1.000 33.035 0 1240 HOH A O    1 ? 
HETATM 8593 O O    . HOH I 7 .   ? -33.429 -13.848 -9.000  1.000 24.524 0 1241 HOH A O    1 ? 
HETATM 8594 O O    . HOH I 7 .   ? -22.482 13.134  14.573  1.000 44.251 0 1242 HOH A O    1 ? 
HETATM 8595 O O    . HOH I 7 .   ? -22.491 3.584   17.314  1.000 35.416 0 1243 HOH A O    1 ? 
HETATM 8596 O O    . HOH I 7 .   ? -25.741 -9.545  9.262   1.000 18.380 0 1244 HOH A O    1 ? 
HETATM 8597 O O    . HOH I 7 .   ? -8.383  13.983  -5.454  1.000 35.105 0 1245 HOH A O    1 ? 
HETATM 8598 O O    . HOH I 7 .   ? -13.631 -32.239 -40.284 1.000 36.081 0 1246 HOH A O    1 ? 
HETATM 8599 O O    . HOH I 7 .   ? -18.279 -13.854 -2.461  1.000 38.045 0 1247 HOH A O    1 ? 
HETATM 8600 O O    . HOH I 7 .   ? -29.629 -32.821 -12.550 1.000 26.562 0 1248 HOH A O    1 ? 
HETATM 8601 O O    . HOH I 7 .   ? -7.366  17.427  -10.797 1.000 40.580 0 1249 HOH A O    1 ? 
HETATM 8602 O O    . HOH I 7 .   ? -28.145 -44.130 -27.053 1.000 34.688 0 1250 HOH A O    1 ? 
HETATM 8603 O O    . HOH I 7 .   ? -9.172  -1.044  -5.300  1.000 8.912  0 1251 HOH A O    1 ? 
HETATM 8604 O O    . HOH I 7 .   ? -31.270 -21.656 -18.787 1.000 26.765 0 1252 HOH A O    1 ? 
HETATM 8605 O O    . HOH I 7 .   ? -33.296 -17.007 -10.980 1.000 40.037 0 1253 HOH A O    1 ? 
HETATM 8606 O O    . HOH I 7 .   ? -19.719 -14.362 11.313  1.000 40.509 0 1254 HOH A O    1 ? 
HETATM 8607 O O    . HOH I 7 .   ? -16.216 -15.562 -7.380  1.000 37.888 0 1255 HOH A O    1 ? 
HETATM 8608 O O    . HOH I 7 .   ? -30.266 -20.192 -20.762 1.000 30.737 0 1256 HOH A O    1 ? 
HETATM 8609 O O    . HOH I 7 .   ? -6.862  16.398  7.970   1.000 32.087 0 1257 HOH A O    1 ? 
HETATM 8610 O O    . HOH I 7 .   ? -25.878 -14.791 1.621   1.000 24.397 0 1258 HOH A O    1 ? 
HETATM 8611 O O    . HOH I 7 .   ? -6.904  13.074  14.125  1.000 31.838 0 1259 HOH A O    1 ? 
HETATM 8612 O O    . HOH I 7 .   ? -11.801 -35.957 -42.386 1.000 39.280 0 1260 HOH A O    1 ? 
HETATM 8613 O O    . HOH I 7 .   ? -8.995  9.342   -22.991 1.000 42.250 0 1261 HOH A O    1 ? 
HETATM 8614 O O    . HOH I 7 .   ? -30.079 -32.711 -32.300 1.000 35.448 0 1262 HOH A O    1 ? 
HETATM 8615 O O    . HOH I 7 .   ? -25.395 -24.390 -5.390  1.000 42.037 0 1263 HOH A O    1 ? 
HETATM 8616 O O    . HOH I 7 .   ? -0.438  -12.068 -7.898  1.000 39.654 0 1264 HOH A O    1 ? 
HETATM 8617 O O    . HOH I 7 .   ? -13.760 8.769   -20.444 1.000 36.521 0 1265 HOH A O    1 ? 
HETATM 8618 O O    . HOH I 7 .   ? -33.106 -45.471 -29.462 1.000 37.252 0 1266 HOH A O    1 ? 
HETATM 8619 O O    . HOH I 7 .   ? -27.644 4.353   11.519  1.000 46.646 0 1267 HOH A O    1 ? 
HETATM 8620 O O    . HOH I 7 .   ? -26.353 11.006  7.974   1.000 41.416 0 1268 HOH A O    1 ? 
HETATM 8621 O O    . HOH I 7 .   ? -26.066 -7.120  10.560  1.000 15.929 0 1269 HOH A O    1 ? 
HETATM 8622 O O    . HOH I 7 .   ? -26.472 4.952   16.268  1.000 37.973 0 1270 HOH A O    1 ? 
HETATM 8623 O O    . HOH I 7 .   ? -28.876 -5.861  -0.929  1.000 25.392 0 1271 HOH A O    1 ? 
HETATM 8624 O O    . HOH I 7 .   ? -7.816  -11.932 7.692   1.000 35.440 0 1272 HOH A O    1 ? 
HETATM 8625 O O    . HOH I 7 .   ? -19.959 6.440   -21.975 1.000 39.283 0 1273 HOH A O    1 ? 
HETATM 8626 O O    . HOH I 7 .   ? -19.649 7.521   -19.535 1.000 34.082 0 1274 HOH A O    1 ? 
HETATM 8627 O O    . HOH I 7 .   ? -15.242 15.437  12.423  1.000 36.263 0 1275 HOH A O    1 ? 
HETATM 8628 O O    . HOH I 7 .   ? -18.093 3.158   -18.757 1.000 24.970 0 1276 HOH A O    1 ? 
HETATM 8629 O O    . HOH I 7 .   ? -31.712 -37.133 -30.817 1.000 35.453 0 1277 HOH A O    1 ? 
HETATM 8630 O O    . HOH I 7 .   ? -26.718 1.355   14.729  1.000 46.179 0 1278 HOH A O    1 ? 
HETATM 8631 O O    . HOH I 7 .   ? -31.390 -0.122  -1.133  1.000 39.079 0 1279 HOH A O    1 ? 
HETATM 8632 O O    . HOH I 7 .   ? -12.496 5.429   16.915  1.000 35.632 0 1280 HOH A O    1 ? 
HETATM 8633 O O    . HOH I 7 .   ? -18.211 -28.616 -9.920  1.000 39.949 0 1281 HOH A O    1 ? 
HETATM 8634 O O    . HOH I 7 .   ? -15.624 -27.569 -9.062  1.000 37.018 0 1282 HOH A O    1 ? 
HETATM 8635 O O    . HOH I 7 .   ? -22.923 10.440  -14.820 1.000 40.350 0 1283 HOH A O    1 ? 
HETATM 8636 O O    . HOH I 7 .   ? -24.975 -9.880  -27.214 1.000 30.929 0 1284 HOH A O    1 ? 
HETATM 8637 O O    . HOH I 7 .   ? 12.184  14.701  -4.994  1.000 39.863 0 1285 HOH A O    1 ? 
HETATM 8638 O O    . HOH I 7 .   ? -29.094 -21.281 -5.233  1.000 39.474 0 1286 HOH A O    1 ? 
HETATM 8639 O O    . HOH I 7 .   ? -3.529  -29.316 -9.270  1.000 31.678 0 1287 HOH A O    1 ? 
HETATM 8640 O O    . HOH I 7 .   ? -25.188 13.062  -0.600  1.000 44.494 0 1288 HOH A O    1 ? 
HETATM 8641 O O    . HOH I 7 .   ? -22.902 12.935  -13.346 1.000 42.649 0 1289 HOH A O    1 ? 
HETATM 8642 O O    . HOH I 7 .   ? -28.302 -34.828 -16.235 1.000 21.701 0 1290 HOH A O    1 ? 
HETATM 8643 O O    . HOH I 7 .   ? -13.857 -47.281 -36.341 1.000 40.088 0 1291 HOH A O    1 ? 
HETATM 8644 O O    . HOH I 7 .   ? -21.961 19.634  -2.912  1.000 46.613 0 1292 HOH A O    1 ? 
HETATM 8645 O O    . HOH I 7 .   ? -12.077 -37.342 -9.065  1.000 51.862 0 1293 HOH A O    1 ? 
HETATM 8646 O O    . HOH I 7 .   ? -21.863 -16.263 9.319   1.000 42.307 0 1294 HOH A O    1 ? 
HETATM 8647 O O    . HOH I 7 .   ? -25.775 -12.328 0.592   1.000 19.120 0 1295 HOH A O    1 ? 
HETATM 8648 O O    . HOH I 7 .   ? -31.660 -4.691  -0.522  1.000 33.966 0 1296 HOH A O    1 ? 
HETATM 8649 O O    . HOH I 7 .   ? -27.846 8.973   -2.131  1.000 34.095 0 1297 HOH A O    1 ? 
HETATM 8650 O O    . HOH I 7 .   ? -33.534 -2.703  11.219  1.000 34.062 0 1298 HOH A O    1 ? 
HETATM 8651 O O    . HOH I 7 .   ? 5.655   22.886  -14.211 1.000 43.389 0 1299 HOH A O    1 ? 
HETATM 8652 O O    . HOH I 7 .   ? -7.691  7.240   -21.127 1.000 18.720 0 1300 HOH A O    1 ? 
HETATM 8653 O O    . HOH I 7 .   ? -17.782 -16.556 -32.329 1.000 30.421 0 1301 HOH A O    1 ? 
HETATM 8654 O O    . HOH I 7 .   ? -14.337 -11.575 -7.519  1.000 26.554 0 1302 HOH A O    1 ? 
HETATM 8655 O O    . HOH I 7 .   ? 12.001  6.618   -15.141 1.000 29.223 0 1303 HOH A O    1 ? 
HETATM 8656 O O    . HOH I 7 .   ? 1.759   18.298  -4.891  1.000 33.390 0 1304 HOH A O    1 ? 
HETATM 8657 O O    . HOH I 7 .   ? -29.333 -45.790 -20.973 1.000 41.299 0 1305 HOH A O    1 ? 
HETATM 8658 O O    . HOH I 7 .   ? -26.050 -5.600  8.203   1.000 16.462 0 1306 HOH A O    1 ? 
HETATM 8659 O O    . HOH I 7 .   ? -10.411 4.949   -23.740 1.000 32.313 0 1307 HOH A O    1 ? 
HETATM 8660 O O    . HOH I 7 .   ? -23.976 1.593   18.795  1.000 31.701 0 1308 HOH A O    1 ? 
HETATM 8661 O O    . HOH I 7 .   ? -12.533 -46.690 -33.969 1.000 23.436 0 1309 HOH A O    1 ? 
HETATM 8662 O O    . HOH I 7 .   ? 2.555   24.583  -18.509 1.000 41.670 0 1310 HOH A O    1 ? 
HETATM 8663 O O    . HOH I 7 .   ? -4.008  14.138  10.451  1.000 28.391 0 1311 HOH A O    1 ? 
HETATM 8664 O O    . HOH I 7 .   ? -29.115 0.839   -2.123  1.000 22.592 0 1312 HOH A O    1 ? 
HETATM 8665 O O    . HOH I 7 .   ? 1.907   11.858  7.785   1.000 30.712 0 1313 HOH A O    1 ? 
HETATM 8666 O O    . HOH I 7 .   ? -20.486 -2.088  22.218  1.000 35.067 0 1314 HOH A O    1 ? 
HETATM 8667 O O    . HOH I 7 .   ? -23.326 -16.024 2.313   1.000 28.602 0 1315 HOH A O    1 ? 
HETATM 8668 O O    . HOH I 7 .   ? -9.902  -45.946 -36.962 1.000 28.311 0 1316 HOH A O    1 ? 
HETATM 8669 O O    . HOH I 7 .   ? -11.586 2.919   -24.798 1.000 38.396 0 1317 HOH A O    1 ? 
HETATM 8670 O O    . HOH I 7 .   ? -10.978 -13.632 -6.525  1.000 48.014 0 1318 HOH A O    1 ? 
HETATM 8671 O O    . HOH I 7 .   ? -29.778 -2.589  -4.119  1.000 15.872 0 1319 HOH A O    1 ? 
HETATM 8672 O O    . HOH I 7 .   ? -21.346 9.709   -17.187 1.000 35.015 0 1320 HOH A O    1 ? 
HETATM 8673 O O    . HOH I 7 .   ? -26.947 7.833   -7.829  1.000 30.740 0 1321 HOH A O    1 ? 
HETATM 8674 O O    . HOH I 7 .   ? 0.763   20.223  -6.398  1.000 47.592 0 1322 HOH A O    1 ? 
HETATM 8675 O O    . HOH I 7 .   ? -24.315 -16.606 6.766   1.000 46.490 0 1323 HOH A O    1 ? 
HETATM 8676 O O    . HOH I 7 .   ? -14.371 -13.684 -5.986  1.000 42.256 0 1324 HOH A O    1 ? 
HETATM 8677 O O    . HOH I 7 .   ? -3.576  -12.741 -8.419  1.000 40.241 0 1325 HOH A O    1 ? 
HETATM 8678 O O    . HOH I 7 .   ? -33.418 -21.514 -23.144 1.000 40.781 0 1326 HOH A O    1 ? 
HETATM 8679 O O    . HOH I 7 .   ? -31.728 -2.451  -2.298  1.000 27.411 0 1327 HOH A O    1 ? 
HETATM 8680 O O    . HOH I 7 .   ? -15.108 -19.903 -7.953  1.000 36.985 0 1328 HOH A O    1 ? 
HETATM 8681 O O    . HOH I 7 .   ? 0.867   13.105  11.668  1.000 46.734 0 1329 HOH A O    1 ? 
HETATM 8682 O O    . HOH I 7 .   ? -28.351 5.672   -3.886  1.000 44.435 0 1330 HOH A O    1 ? 
HETATM 8683 O O    . HOH I 7 .   ? -28.855 -52.872 -13.578 1.000 45.474 0 1331 HOH A O    1 ? 
HETATM 8684 O O    . HOH I 7 .   ? -9.975  15.985  15.059  1.000 47.902 0 1332 HOH A O    1 ? 
HETATM 8685 O O    . HOH I 7 .   ? -14.150 -3.132  -33.137 1.000 45.763 0 1333 HOH A O    1 ? 
HETATM 8686 O O    . HOH I 7 .   ? -6.343  17.590  12.648  1.000 49.061 0 1334 HOH A O    1 ? 
# 
