data_8V2J
# 
_entry.id   8V2J 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.399 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8V2J         pdb_00008v2j 10.2210/pdb8v2j/pdb 
WWPDB D_1000279340 ?            ?                   
EMDB  EMD-42916    ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2024-11-27 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8V2J 
_pdbx_database_status.recvd_initial_deposition_date   2023-11-22 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
loop_
_pdbx_database_related.db_name 
_pdbx_database_related.details 
_pdbx_database_related.db_id 
_pdbx_database_related.content_type 
EMDB 'Structure of alpha1B and betaI/IVb microtubule bound to GMPCPP' EMD-44762 'other EM volume'      
PDB  'Structure of alpha1B and betaI/IVb microtubule bound to GMPCPP' 9BP6      unspecified            
EMDB 'Structure of alpha1B and betaI/IVb microtubule bound to GDP'    EMD-42916 'associated EM volume' 
# 
_pdbx_contact_author.id                 3 
_pdbx_contact_author.email              antonina@ninds.nih.gov 
_pdbx_contact_author.name_first         Antonina 
_pdbx_contact_author.name_last          Roll-Mecak 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-2621-7307 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Zehr, E.A.'     1 0000-0002-9768-5792 
'Roll-Mecak, A.' 2 0000-0003-2621-7307 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To be published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
;Cryo-EM structures of human a1B/bI+bIVb and a1A/bIII microtubules show tubulin tails link tubulin dimers  and shed light on isoform specific assembly
;
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Zehr, E.A.'     1 0000-0002-9768-5792 
primary 'Roll-Mecak, A.' 2 0000-0003-2621-7307 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     nat 'Tubulin beta chain'        49717.629 2 ? ? ? ? 
2 polymer     nat 'Tubulin alpha-1B chain'    50204.445 2 ? ? ? ? 
3 non-polymer syn "GUANOSINE-5'-DIPHOSPHATE"  443.201   2 ? ? ? ? 
4 non-polymer syn "GUANOSINE-5'-TRIPHOSPHATE" 523.180   2 ? ? ? ? 
5 non-polymer syn 'MAGNESIUM ION'             24.305    2 ? ? ? ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
1 'Tubulin beta-5 chain'                                                      
2 'Alpha-tubulin ubiquitous,Tubulin K-alpha-1,Tubulin alpha-ubiquitous chain' 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLDRISVYYNEATGGKYVPRAILVDLEPGTMDSVRSGP
FGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYP
DRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL
RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQVFDAKNMMAACDPRHGRYLTVAAVFRGR
MSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMAVTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTG
EGMDEMEFTEAESNMNDLVSEYQQYQDATAEEEEDFGEEAEEEA
;
;MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLDRISVYYNEATGGKYVPRAILVDLEPGTMDSVRSGP
FGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYP
DRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL
RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQVFDAKNMMAACDPRHGRYLTVAAVFRGR
MSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMAVTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTG
EGMDEMEFTEAESNMNDLVSEYQQYQDATAEEEEDFGEEAEEEA
;
B,E ? 
2 'polypeptide(L)' no no 
;MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRT
GTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVD
YGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITA
SLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYR
GDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYA
KRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSVEGEGEEEGEEY
;
;MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRT
GTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVD
YGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITA
SLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYR
GDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYA
KRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSVEGEGEEEGEEY
;
A,D ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
3 "GUANOSINE-5'-DIPHOSPHATE"  GDP 
4 "GUANOSINE-5'-TRIPHOSPHATE" GTP 
5 'MAGNESIUM ION'             MG  
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   ARG n 
1 3   GLU n 
1 4   ILE n 
1 5   VAL n 
1 6   HIS n 
1 7   ILE n 
1 8   GLN n 
1 9   ALA n 
1 10  GLY n 
1 11  GLN n 
1 12  CYS n 
1 13  GLY n 
1 14  ASN n 
1 15  GLN n 
1 16  ILE n 
1 17  GLY n 
1 18  ALA n 
1 19  LYS n 
1 20  PHE n 
1 21  TRP n 
1 22  GLU n 
1 23  VAL n 
1 24  ILE n 
1 25  SER n 
1 26  ASP n 
1 27  GLU n 
1 28  HIS n 
1 29  GLY n 
1 30  ILE n 
1 31  ASP n 
1 32  PRO n 
1 33  THR n 
1 34  GLY n 
1 35  THR n 
1 36  TYR n 
1 37  HIS n 
1 38  GLY n 
1 39  ASP n 
1 40  SER n 
1 41  ASP n 
1 42  LEU n 
1 43  GLN n 
1 44  LEU n 
1 45  ASP n 
1 46  ARG n 
1 47  ILE n 
1 48  SER n 
1 49  VAL n 
1 50  TYR n 
1 51  TYR n 
1 52  ASN n 
1 53  GLU n 
1 54  ALA n 
1 55  THR n 
1 56  GLY n 
1 57  GLY n 
1 58  LYS n 
1 59  TYR n 
1 60  VAL n 
1 61  PRO n 
1 62  ARG n 
1 63  ALA n 
1 64  ILE n 
1 65  LEU n 
1 66  VAL n 
1 67  ASP n 
1 68  LEU n 
1 69  GLU n 
1 70  PRO n 
1 71  GLY n 
1 72  THR n 
1 73  MET n 
1 74  ASP n 
1 75  SER n 
1 76  VAL n 
1 77  ARG n 
1 78  SER n 
1 79  GLY n 
1 80  PRO n 
1 81  PHE n 
1 82  GLY n 
1 83  GLN n 
1 84  ILE n 
1 85  PHE n 
1 86  ARG n 
1 87  PRO n 
1 88  ASP n 
1 89  ASN n 
1 90  PHE n 
1 91  VAL n 
1 92  PHE n 
1 93  GLY n 
1 94  GLN n 
1 95  SER n 
1 96  GLY n 
1 97  ALA n 
1 98  GLY n 
1 99  ASN n 
1 100 ASN n 
1 101 TRP n 
1 102 ALA n 
1 103 LYS n 
1 104 GLY n 
1 105 HIS n 
1 106 TYR n 
1 107 THR n 
1 108 GLU n 
1 109 GLY n 
1 110 ALA n 
1 111 GLU n 
1 112 LEU n 
1 113 VAL n 
1 114 ASP n 
1 115 SER n 
1 116 VAL n 
1 117 LEU n 
1 118 ASP n 
1 119 VAL n 
1 120 VAL n 
1 121 ARG n 
1 122 LYS n 
1 123 GLU n 
1 124 ALA n 
1 125 GLU n 
1 126 SER n 
1 127 CYS n 
1 128 ASP n 
1 129 CYS n 
1 130 LEU n 
1 131 GLN n 
1 132 GLY n 
1 133 PHE n 
1 134 GLN n 
1 135 LEU n 
1 136 THR n 
1 137 HIS n 
1 138 SER n 
1 139 LEU n 
1 140 GLY n 
1 141 GLY n 
1 142 GLY n 
1 143 THR n 
1 144 GLY n 
1 145 SER n 
1 146 GLY n 
1 147 MET n 
1 148 GLY n 
1 149 THR n 
1 150 LEU n 
1 151 LEU n 
1 152 ILE n 
1 153 SER n 
1 154 LYS n 
1 155 ILE n 
1 156 ARG n 
1 157 GLU n 
1 158 GLU n 
1 159 TYR n 
1 160 PRO n 
1 161 ASP n 
1 162 ARG n 
1 163 ILE n 
1 164 MET n 
1 165 ASN n 
1 166 THR n 
1 167 PHE n 
1 168 SER n 
1 169 VAL n 
1 170 VAL n 
1 171 PRO n 
1 172 SER n 
1 173 PRO n 
1 174 LYS n 
1 175 VAL n 
1 176 SER n 
1 177 ASP n 
1 178 THR n 
1 179 VAL n 
1 180 VAL n 
1 181 GLU n 
1 182 PRO n 
1 183 TYR n 
1 184 ASN n 
1 185 ALA n 
1 186 THR n 
1 187 LEU n 
1 188 SER n 
1 189 VAL n 
1 190 HIS n 
1 191 GLN n 
1 192 LEU n 
1 193 VAL n 
1 194 GLU n 
1 195 ASN n 
1 196 THR n 
1 197 ASP n 
1 198 GLU n 
1 199 THR n 
1 200 TYR n 
1 201 CYS n 
1 202 ILE n 
1 203 ASP n 
1 204 ASN n 
1 205 GLU n 
1 206 ALA n 
1 207 LEU n 
1 208 TYR n 
1 209 ASP n 
1 210 ILE n 
1 211 CYS n 
1 212 PHE n 
1 213 ARG n 
1 214 THR n 
1 215 LEU n 
1 216 LYS n 
1 217 LEU n 
1 218 THR n 
1 219 THR n 
1 220 PRO n 
1 221 THR n 
1 222 TYR n 
1 223 GLY n 
1 224 ASP n 
1 225 LEU n 
1 226 ASN n 
1 227 HIS n 
1 228 LEU n 
1 229 VAL n 
1 230 SER n 
1 231 ALA n 
1 232 THR n 
1 233 MET n 
1 234 SER n 
1 235 GLY n 
1 236 VAL n 
1 237 THR n 
1 238 THR n 
1 239 CYS n 
1 240 LEU n 
1 241 ARG n 
1 242 PHE n 
1 243 PRO n 
1 244 GLY n 
1 245 GLN n 
1 246 LEU n 
1 247 ASN n 
1 248 ALA n 
1 249 ASP n 
1 250 LEU n 
1 251 ARG n 
1 252 LYS n 
1 253 LEU n 
1 254 ALA n 
1 255 VAL n 
1 256 ASN n 
1 257 MET n 
1 258 VAL n 
1 259 PRO n 
1 260 PHE n 
1 261 PRO n 
1 262 ARG n 
1 263 LEU n 
1 264 HIS n 
1 265 PHE n 
1 266 PHE n 
1 267 MET n 
1 268 PRO n 
1 269 GLY n 
1 270 PHE n 
1 271 ALA n 
1 272 PRO n 
1 273 LEU n 
1 274 THR n 
1 275 SER n 
1 276 ARG n 
1 277 GLY n 
1 278 SER n 
1 279 GLN n 
1 280 GLN n 
1 281 TYR n 
1 282 ARG n 
1 283 ALA n 
1 284 LEU n 
1 285 THR n 
1 286 VAL n 
1 287 PRO n 
1 288 GLU n 
1 289 LEU n 
1 290 THR n 
1 291 GLN n 
1 292 GLN n 
1 293 VAL n 
1 294 PHE n 
1 295 ASP n 
1 296 ALA n 
1 297 LYS n 
1 298 ASN n 
1 299 MET n 
1 300 MET n 
1 301 ALA n 
1 302 ALA n 
1 303 CYS n 
1 304 ASP n 
1 305 PRO n 
1 306 ARG n 
1 307 HIS n 
1 308 GLY n 
1 309 ARG n 
1 310 TYR n 
1 311 LEU n 
1 312 THR n 
1 313 VAL n 
1 314 ALA n 
1 315 ALA n 
1 316 VAL n 
1 317 PHE n 
1 318 ARG n 
1 319 GLY n 
1 320 ARG n 
1 321 MET n 
1 322 SER n 
1 323 MET n 
1 324 LYS n 
1 325 GLU n 
1 326 VAL n 
1 327 ASP n 
1 328 GLU n 
1 329 GLN n 
1 330 MET n 
1 331 LEU n 
1 332 ASN n 
1 333 VAL n 
1 334 GLN n 
1 335 ASN n 
1 336 LYS n 
1 337 ASN n 
1 338 SER n 
1 339 SER n 
1 340 TYR n 
1 341 PHE n 
1 342 VAL n 
1 343 GLU n 
1 344 TRP n 
1 345 ILE n 
1 346 PRO n 
1 347 ASN n 
1 348 ASN n 
1 349 VAL n 
1 350 LYS n 
1 351 THR n 
1 352 ALA n 
1 353 VAL n 
1 354 CYS n 
1 355 ASP n 
1 356 ILE n 
1 357 PRO n 
1 358 PRO n 
1 359 ARG n 
1 360 GLY n 
1 361 LEU n 
1 362 LYS n 
1 363 MET n 
1 364 ALA n 
1 365 VAL n 
1 366 THR n 
1 367 PHE n 
1 368 ILE n 
1 369 GLY n 
1 370 ASN n 
1 371 SER n 
1 372 THR n 
1 373 ALA n 
1 374 ILE n 
1 375 GLN n 
1 376 GLU n 
1 377 LEU n 
1 378 PHE n 
1 379 LYS n 
1 380 ARG n 
1 381 ILE n 
1 382 SER n 
1 383 GLU n 
1 384 GLN n 
1 385 PHE n 
1 386 THR n 
1 387 ALA n 
1 388 MET n 
1 389 PHE n 
1 390 ARG n 
1 391 ARG n 
1 392 LYS n 
1 393 ALA n 
1 394 PHE n 
1 395 LEU n 
1 396 HIS n 
1 397 TRP n 
1 398 TYR n 
1 399 THR n 
1 400 GLY n 
1 401 GLU n 
1 402 GLY n 
1 403 MET n 
1 404 ASP n 
1 405 GLU n 
1 406 MET n 
1 407 GLU n 
1 408 PHE n 
1 409 THR n 
1 410 GLU n 
1 411 ALA n 
1 412 GLU n 
1 413 SER n 
1 414 ASN n 
1 415 MET n 
1 416 ASN n 
1 417 ASP n 
1 418 LEU n 
1 419 VAL n 
1 420 SER n 
1 421 GLU n 
1 422 TYR n 
1 423 GLN n 
1 424 GLN n 
1 425 TYR n 
1 426 GLN n 
1 427 ASP n 
1 428 ALA n 
1 429 THR n 
1 430 ALA n 
1 431 GLU n 
1 432 GLU n 
1 433 GLU n 
1 434 GLU n 
1 435 ASP n 
1 436 PHE n 
1 437 GLY n 
1 438 GLU n 
1 439 GLU n 
1 440 ALA n 
1 441 GLU n 
1 442 GLU n 
1 443 GLU n 
1 444 ALA n 
2 1   MET n 
2 2   ARG n 
2 3   GLU n 
2 4   CYS n 
2 5   ILE n 
2 6   SER n 
2 7   ILE n 
2 8   HIS n 
2 9   VAL n 
2 10  GLY n 
2 11  GLN n 
2 12  ALA n 
2 13  GLY n 
2 14  VAL n 
2 15  GLN n 
2 16  ILE n 
2 17  GLY n 
2 18  ASN n 
2 19  ALA n 
2 20  CYS n 
2 21  TRP n 
2 22  GLU n 
2 23  LEU n 
2 24  TYR n 
2 25  CYS n 
2 26  LEU n 
2 27  GLU n 
2 28  HIS n 
2 29  GLY n 
2 30  ILE n 
2 31  GLN n 
2 32  PRO n 
2 33  ASP n 
2 34  GLY n 
2 35  GLN n 
2 36  MET n 
2 37  PRO n 
2 38  SER n 
2 39  ASP n 
2 40  LYS n 
2 41  THR n 
2 42  ILE n 
2 43  GLY n 
2 44  GLY n 
2 45  GLY n 
2 46  ASP n 
2 47  ASP n 
2 48  SER n 
2 49  PHE n 
2 50  ASN n 
2 51  THR n 
2 52  PHE n 
2 53  PHE n 
2 54  SER n 
2 55  GLU n 
2 56  THR n 
2 57  GLY n 
2 58  ALA n 
2 59  GLY n 
2 60  LYS n 
2 61  HIS n 
2 62  VAL n 
2 63  PRO n 
2 64  ARG n 
2 65  ALA n 
2 66  VAL n 
2 67  PHE n 
2 68  VAL n 
2 69  ASP n 
2 70  LEU n 
2 71  GLU n 
2 72  PRO n 
2 73  THR n 
2 74  VAL n 
2 75  ILE n 
2 76  ASP n 
2 77  GLU n 
2 78  VAL n 
2 79  ARG n 
2 80  THR n 
2 81  GLY n 
2 82  THR n 
2 83  TYR n 
2 84  ARG n 
2 85  GLN n 
2 86  LEU n 
2 87  PHE n 
2 88  HIS n 
2 89  PRO n 
2 90  GLU n 
2 91  GLN n 
2 92  LEU n 
2 93  ILE n 
2 94  THR n 
2 95  GLY n 
2 96  LYS n 
2 97  GLU n 
2 98  ASP n 
2 99  ALA n 
2 100 ALA n 
2 101 ASN n 
2 102 ASN n 
2 103 TYR n 
2 104 ALA n 
2 105 ARG n 
2 106 GLY n 
2 107 HIS n 
2 108 TYR n 
2 109 THR n 
2 110 ILE n 
2 111 GLY n 
2 112 LYS n 
2 113 GLU n 
2 114 ILE n 
2 115 ILE n 
2 116 ASP n 
2 117 LEU n 
2 118 VAL n 
2 119 LEU n 
2 120 ASP n 
2 121 ARG n 
2 122 ILE n 
2 123 ARG n 
2 124 LYS n 
2 125 LEU n 
2 126 ALA n 
2 127 ASP n 
2 128 GLN n 
2 129 CYS n 
2 130 THR n 
2 131 GLY n 
2 132 LEU n 
2 133 GLN n 
2 134 GLY n 
2 135 PHE n 
2 136 LEU n 
2 137 VAL n 
2 138 PHE n 
2 139 HIS n 
2 140 SER n 
2 141 PHE n 
2 142 GLY n 
2 143 GLY n 
2 144 GLY n 
2 145 THR n 
2 146 GLY n 
2 147 SER n 
2 148 GLY n 
2 149 PHE n 
2 150 THR n 
2 151 SER n 
2 152 LEU n 
2 153 LEU n 
2 154 MET n 
2 155 GLU n 
2 156 ARG n 
2 157 LEU n 
2 158 SER n 
2 159 VAL n 
2 160 ASP n 
2 161 TYR n 
2 162 GLY n 
2 163 LYS n 
2 164 LYS n 
2 165 SER n 
2 166 LYS n 
2 167 LEU n 
2 168 GLU n 
2 169 PHE n 
2 170 SER n 
2 171 ILE n 
2 172 TYR n 
2 173 PRO n 
2 174 ALA n 
2 175 PRO n 
2 176 GLN n 
2 177 VAL n 
2 178 SER n 
2 179 THR n 
2 180 ALA n 
2 181 VAL n 
2 182 VAL n 
2 183 GLU n 
2 184 PRO n 
2 185 TYR n 
2 186 ASN n 
2 187 SER n 
2 188 ILE n 
2 189 LEU n 
2 190 THR n 
2 191 THR n 
2 192 HIS n 
2 193 THR n 
2 194 THR n 
2 195 LEU n 
2 196 GLU n 
2 197 HIS n 
2 198 SER n 
2 199 ASP n 
2 200 CYS n 
2 201 ALA n 
2 202 PHE n 
2 203 MET n 
2 204 VAL n 
2 205 ASP n 
2 206 ASN n 
2 207 GLU n 
2 208 ALA n 
2 209 ILE n 
2 210 TYR n 
2 211 ASP n 
2 212 ILE n 
2 213 CYS n 
2 214 ARG n 
2 215 ARG n 
2 216 ASN n 
2 217 LEU n 
2 218 ASP n 
2 219 ILE n 
2 220 GLU n 
2 221 ARG n 
2 222 PRO n 
2 223 THR n 
2 224 TYR n 
2 225 THR n 
2 226 ASN n 
2 227 LEU n 
2 228 ASN n 
2 229 ARG n 
2 230 LEU n 
2 231 ILE n 
2 232 SER n 
2 233 GLN n 
2 234 ILE n 
2 235 VAL n 
2 236 SER n 
2 237 SER n 
2 238 ILE n 
2 239 THR n 
2 240 ALA n 
2 241 SER n 
2 242 LEU n 
2 243 ARG n 
2 244 PHE n 
2 245 ASP n 
2 246 GLY n 
2 247 ALA n 
2 248 LEU n 
2 249 ASN n 
2 250 VAL n 
2 251 ASP n 
2 252 LEU n 
2 253 THR n 
2 254 GLU n 
2 255 PHE n 
2 256 GLN n 
2 257 THR n 
2 258 ASN n 
2 259 LEU n 
2 260 VAL n 
2 261 PRO n 
2 262 TYR n 
2 263 PRO n 
2 264 ARG n 
2 265 ILE n 
2 266 HIS n 
2 267 PHE n 
2 268 PRO n 
2 269 LEU n 
2 270 ALA n 
2 271 THR n 
2 272 TYR n 
2 273 ALA n 
2 274 PRO n 
2 275 VAL n 
2 276 ILE n 
2 277 SER n 
2 278 ALA n 
2 279 GLU n 
2 280 LYS n 
2 281 ALA n 
2 282 TYR n 
2 283 HIS n 
2 284 GLU n 
2 285 GLN n 
2 286 LEU n 
2 287 SER n 
2 288 VAL n 
2 289 ALA n 
2 290 GLU n 
2 291 ILE n 
2 292 THR n 
2 293 ASN n 
2 294 ALA n 
2 295 CYS n 
2 296 PHE n 
2 297 GLU n 
2 298 PRO n 
2 299 ALA n 
2 300 ASN n 
2 301 GLN n 
2 302 MET n 
2 303 VAL n 
2 304 LYS n 
2 305 CYS n 
2 306 ASP n 
2 307 PRO n 
2 308 ARG n 
2 309 HIS n 
2 310 GLY n 
2 311 LYS n 
2 312 TYR n 
2 313 MET n 
2 314 ALA n 
2 315 CYS n 
2 316 CYS n 
2 317 LEU n 
2 318 LEU n 
2 319 TYR n 
2 320 ARG n 
2 321 GLY n 
2 322 ASP n 
2 323 VAL n 
2 324 VAL n 
2 325 PRO n 
2 326 LYS n 
2 327 ASP n 
2 328 VAL n 
2 329 ASN n 
2 330 ALA n 
2 331 ALA n 
2 332 ILE n 
2 333 ALA n 
2 334 THR n 
2 335 ILE n 
2 336 LYS n 
2 337 THR n 
2 338 LYS n 
2 339 ARG n 
2 340 SER n 
2 341 ILE n 
2 342 GLN n 
2 343 PHE n 
2 344 VAL n 
2 345 ASP n 
2 346 TRP n 
2 347 CYS n 
2 348 PRO n 
2 349 THR n 
2 350 GLY n 
2 351 PHE n 
2 352 LYS n 
2 353 VAL n 
2 354 GLY n 
2 355 ILE n 
2 356 ASN n 
2 357 TYR n 
2 358 GLN n 
2 359 PRO n 
2 360 PRO n 
2 361 THR n 
2 362 VAL n 
2 363 VAL n 
2 364 PRO n 
2 365 GLY n 
2 366 GLY n 
2 367 ASP n 
2 368 LEU n 
2 369 ALA n 
2 370 LYS n 
2 371 VAL n 
2 372 GLN n 
2 373 ARG n 
2 374 ALA n 
2 375 VAL n 
2 376 CYS n 
2 377 MET n 
2 378 LEU n 
2 379 SER n 
2 380 ASN n 
2 381 THR n 
2 382 THR n 
2 383 ALA n 
2 384 ILE n 
2 385 ALA n 
2 386 GLU n 
2 387 ALA n 
2 388 TRP n 
2 389 ALA n 
2 390 ARG n 
2 391 LEU n 
2 392 ASP n 
2 393 HIS n 
2 394 LYS n 
2 395 PHE n 
2 396 ASP n 
2 397 LEU n 
2 398 MET n 
2 399 TYR n 
2 400 ALA n 
2 401 LYS n 
2 402 ARG n 
2 403 ALA n 
2 404 PHE n 
2 405 VAL n 
2 406 HIS n 
2 407 TRP n 
2 408 TYR n 
2 409 VAL n 
2 410 GLY n 
2 411 GLU n 
2 412 GLY n 
2 413 MET n 
2 414 GLU n 
2 415 GLU n 
2 416 GLY n 
2 417 GLU n 
2 418 PHE n 
2 419 SER n 
2 420 GLU n 
2 421 ALA n 
2 422 ARG n 
2 423 GLU n 
2 424 ASP n 
2 425 MET n 
2 426 ALA n 
2 427 ALA n 
2 428 LEU n 
2 429 GLU n 
2 430 LYS n 
2 431 ASP n 
2 432 TYR n 
2 433 GLU n 
2 434 GLU n 
2 435 VAL n 
2 436 GLY n 
2 437 VAL n 
2 438 ASP n 
2 439 SER n 
2 440 VAL n 
2 441 GLU n 
2 442 GLY n 
2 443 GLU n 
2 444 GLY n 
2 445 GLU n 
2 446 GLU n 
2 447 GLU n 
2 448 GLY n 
2 449 GLU n 
2 450 GLU n 
2 451 TYR n 
# 
loop_
_entity_src_nat.entity_id 
_entity_src_nat.pdbx_src_id 
_entity_src_nat.pdbx_alt_source_flag 
_entity_src_nat.pdbx_beg_seq_num 
_entity_src_nat.pdbx_end_seq_num 
_entity_src_nat.common_name 
_entity_src_nat.pdbx_organism_scientific 
_entity_src_nat.pdbx_ncbi_taxonomy_id 
_entity_src_nat.genus 
_entity_src_nat.species 
_entity_src_nat.strain 
_entity_src_nat.tissue 
_entity_src_nat.tissue_fraction 
_entity_src_nat.pdbx_secretion 
_entity_src_nat.pdbx_fragment 
_entity_src_nat.pdbx_variant 
_entity_src_nat.pdbx_cell_line 
_entity_src_nat.pdbx_atcc 
_entity_src_nat.pdbx_cellular_location 
_entity_src_nat.pdbx_organ 
_entity_src_nat.pdbx_organelle 
_entity_src_nat.pdbx_cell 
_entity_src_nat.pdbx_plasmid_name 
_entity_src_nat.pdbx_plasmid_details 
_entity_src_nat.details 
1 1 sample 1 444 human 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? tsA201 ? ? kidney ? ? ? ? ? 
2 1 sample 1 451 human 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? tsA201 ? ? kidney ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                     ? 'C3 H7 N O2'        89.093  
ARG 'L-peptide linking' y ARGININE                    ? 'C6 H15 N4 O2 1'    175.209 
ASN 'L-peptide linking' y ASPARAGINE                  ? 'C4 H8 N2 O3'       132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'             ? 'C4 H7 N O4'        133.103 
CYS 'L-peptide linking' y CYSTEINE                    ? 'C3 H7 N O2 S'      121.158 
GDP 'RNA linking'       n "GUANOSINE-5'-DIPHOSPHATE"  ? 'C10 H15 N5 O11 P2' 443.201 
GLN 'L-peptide linking' y GLUTAMINE                   ? 'C5 H10 N2 O3'      146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'             ? 'C5 H9 N O4'        147.129 
GLY 'peptide linking'   y GLYCINE                     ? 'C2 H5 N O2'        75.067  
GTP non-polymer         n "GUANOSINE-5'-TRIPHOSPHATE" ? 'C10 H16 N5 O14 P3' 523.180 
HIS 'L-peptide linking' y HISTIDINE                   ? 'C6 H10 N3 O2 1'    156.162 
ILE 'L-peptide linking' y ISOLEUCINE                  ? 'C6 H13 N O2'       131.173 
LEU 'L-peptide linking' y LEUCINE                     ? 'C6 H13 N O2'       131.173 
LYS 'L-peptide linking' y LYSINE                      ? 'C6 H15 N2 O2 1'    147.195 
MET 'L-peptide linking' y METHIONINE                  ? 'C5 H11 N O2 S'     149.211 
MG  non-polymer         . 'MAGNESIUM ION'             ? 'Mg 2'              24.305  
PHE 'L-peptide linking' y PHENYLALANINE               ? 'C9 H11 N O2'       165.189 
PRO 'L-peptide linking' y PROLINE                     ? 'C5 H9 N O2'        115.130 
SER 'L-peptide linking' y SERINE                      ? 'C3 H7 N O3'        105.093 
THR 'L-peptide linking' y THREONINE                   ? 'C4 H9 N O3'        119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                  ? 'C11 H12 N2 O2'     204.225 
TYR 'L-peptide linking' y TYROSINE                    ? 'C9 H11 N O3'       181.189 
VAL 'L-peptide linking' y VALINE                      ? 'C5 H11 N O2'       117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   1   MET MET B . n 
A 1 2   ARG 2   2   2   ARG ARG B . n 
A 1 3   GLU 3   3   3   GLU GLU B . n 
A 1 4   ILE 4   4   4   ILE ILE B . n 
A 1 5   VAL 5   5   5   VAL VAL B . n 
A 1 6   HIS 6   6   6   HIS HIS B . n 
A 1 7   ILE 7   7   7   ILE ILE B . n 
A 1 8   GLN 8   8   8   GLN GLN B . n 
A 1 9   ALA 9   9   9   ALA ALA B . n 
A 1 10  GLY 10  10  10  GLY GLY B . n 
A 1 11  GLN 11  11  11  GLN GLN B . n 
A 1 12  CYS 12  12  12  CYS CYS B . n 
A 1 13  GLY 13  13  13  GLY GLY B . n 
A 1 14  ASN 14  14  14  ASN ASN B . n 
A 1 15  GLN 15  15  15  GLN GLN B . n 
A 1 16  ILE 16  16  16  ILE ILE B . n 
A 1 17  GLY 17  17  17  GLY GLY B . n 
A 1 18  ALA 18  18  18  ALA ALA B . n 
A 1 19  LYS 19  19  19  LYS LYS B . n 
A 1 20  PHE 20  20  20  PHE PHE B . n 
A 1 21  TRP 21  21  21  TRP TRP B . n 
A 1 22  GLU 22  22  22  GLU GLU B . n 
A 1 23  VAL 23  23  23  VAL VAL B . n 
A 1 24  ILE 24  24  24  ILE ILE B . n 
A 1 25  SER 25  25  25  SER SER B . n 
A 1 26  ASP 26  26  26  ASP ASP B . n 
A 1 27  GLU 27  27  27  GLU GLU B . n 
A 1 28  HIS 28  28  28  HIS HIS B . n 
A 1 29  GLY 29  29  29  GLY GLY B . n 
A 1 30  ILE 30  30  30  ILE ILE B . n 
A 1 31  ASP 31  31  31  ASP ASP B . n 
A 1 32  PRO 32  32  32  PRO PRO B . n 
A 1 33  THR 33  33  33  THR THR B . n 
A 1 34  GLY 34  34  34  GLY GLY B . n 
A 1 35  THR 35  35  35  THR THR B . n 
A 1 36  TYR 36  36  36  TYR TYR B . n 
A 1 37  HIS 37  37  37  HIS HIS B . n 
A 1 38  GLY 38  38  38  GLY GLY B . n 
A 1 39  ASP 39  39  39  ASP ASP B . n 
A 1 40  SER 40  40  40  SER SER B . n 
A 1 41  ASP 41  41  41  ASP ASP B . n 
A 1 42  LEU 42  42  42  LEU LEU B . n 
A 1 43  GLN 43  43  43  GLN GLN B . n 
A 1 44  LEU 44  44  44  LEU LEU B . n 
A 1 45  ASP 45  45  45  ASP ASP B . n 
A 1 46  ARG 46  46  46  ARG ARG B . n 
A 1 47  ILE 47  47  47  ILE ILE B . n 
A 1 48  SER 48  48  48  SER SER B . n 
A 1 49  VAL 49  49  49  VAL VAL B . n 
A 1 50  TYR 50  50  50  TYR TYR B . n 
A 1 51  TYR 51  51  51  TYR TYR B . n 
A 1 52  ASN 52  52  52  ASN ASN B . n 
A 1 53  GLU 53  53  53  GLU GLU B . n 
A 1 54  ALA 54  54  54  ALA ALA B . n 
A 1 55  THR 55  55  55  THR THR B . n 
A 1 56  GLY 56  56  56  GLY GLY B . n 
A 1 57  GLY 57  57  57  GLY GLY B . n 
A 1 58  LYS 58  58  58  LYS LYS B . n 
A 1 59  TYR 59  59  59  TYR TYR B . n 
A 1 60  VAL 60  60  60  VAL VAL B . n 
A 1 61  PRO 61  61  61  PRO PRO B . n 
A 1 62  ARG 62  62  62  ARG ARG B . n 
A 1 63  ALA 63  63  63  ALA ALA B . n 
A 1 64  ILE 64  64  64  ILE ILE B . n 
A 1 65  LEU 65  65  65  LEU LEU B . n 
A 1 66  VAL 66  66  66  VAL VAL B . n 
A 1 67  ASP 67  67  67  ASP ASP B . n 
A 1 68  LEU 68  68  68  LEU LEU B . n 
A 1 69  GLU 69  69  69  GLU GLU B . n 
A 1 70  PRO 70  70  70  PRO PRO B . n 
A 1 71  GLY 71  71  71  GLY GLY B . n 
A 1 72  THR 72  72  72  THR THR B . n 
A 1 73  MET 73  73  73  MET MET B . n 
A 1 74  ASP 74  74  74  ASP ASP B . n 
A 1 75  SER 75  75  75  SER SER B . n 
A 1 76  VAL 76  76  76  VAL VAL B . n 
A 1 77  ARG 77  77  77  ARG ARG B . n 
A 1 78  SER 78  78  78  SER SER B . n 
A 1 79  GLY 79  79  79  GLY GLY B . n 
A 1 80  PRO 80  80  80  PRO PRO B . n 
A 1 81  PHE 81  81  81  PHE PHE B . n 
A 1 82  GLY 82  82  82  GLY GLY B . n 
A 1 83  GLN 83  83  83  GLN GLN B . n 
A 1 84  ILE 84  84  84  ILE ILE B . n 
A 1 85  PHE 85  85  85  PHE PHE B . n 
A 1 86  ARG 86  86  86  ARG ARG B . n 
A 1 87  PRO 87  87  87  PRO PRO B . n 
A 1 88  ASP 88  88  88  ASP ASP B . n 
A 1 89  ASN 89  89  89  ASN ASN B . n 
A 1 90  PHE 90  90  90  PHE PHE B . n 
A 1 91  VAL 91  91  91  VAL VAL B . n 
A 1 92  PHE 92  92  92  PHE PHE B . n 
A 1 93  GLY 93  93  93  GLY GLY B . n 
A 1 94  GLN 94  94  94  GLN GLN B . n 
A 1 95  SER 95  95  95  SER SER B . n 
A 1 96  GLY 96  96  96  GLY GLY B . n 
A 1 97  ALA 97  97  97  ALA ALA B . n 
A 1 98  GLY 98  98  98  GLY GLY B . n 
A 1 99  ASN 99  99  99  ASN ASN B . n 
A 1 100 ASN 100 100 100 ASN ASN B . n 
A 1 101 TRP 101 101 101 TRP TRP B . n 
A 1 102 ALA 102 102 102 ALA ALA B . n 
A 1 103 LYS 103 103 103 LYS LYS B . n 
A 1 104 GLY 104 104 104 GLY GLY B . n 
A 1 105 HIS 105 105 105 HIS HIS B . n 
A 1 106 TYR 106 106 106 TYR TYR B . n 
A 1 107 THR 107 107 107 THR THR B . n 
A 1 108 GLU 108 108 108 GLU GLU B . n 
A 1 109 GLY 109 109 109 GLY GLY B . n 
A 1 110 ALA 110 110 110 ALA ALA B . n 
A 1 111 GLU 111 111 111 GLU GLU B . n 
A 1 112 LEU 112 112 112 LEU LEU B . n 
A 1 113 VAL 113 113 113 VAL VAL B . n 
A 1 114 ASP 114 114 114 ASP ASP B . n 
A 1 115 SER 115 115 115 SER SER B . n 
A 1 116 VAL 116 116 116 VAL VAL B . n 
A 1 117 LEU 117 117 117 LEU LEU B . n 
A 1 118 ASP 118 118 118 ASP ASP B . n 
A 1 119 VAL 119 119 119 VAL VAL B . n 
A 1 120 VAL 120 120 120 VAL VAL B . n 
A 1 121 ARG 121 121 121 ARG ARG B . n 
A 1 122 LYS 122 122 122 LYS LYS B . n 
A 1 123 GLU 123 123 123 GLU GLU B . n 
A 1 124 ALA 124 124 124 ALA ALA B . n 
A 1 125 GLU 125 125 125 GLU GLU B . n 
A 1 126 SER 126 126 126 SER SER B . n 
A 1 127 CYS 127 127 127 CYS CYS B . n 
A 1 128 ASP 128 128 128 ASP ASP B . n 
A 1 129 CYS 129 129 129 CYS CYS B . n 
A 1 130 LEU 130 130 130 LEU LEU B . n 
A 1 131 GLN 131 131 131 GLN GLN B . n 
A 1 132 GLY 132 132 132 GLY GLY B . n 
A 1 133 PHE 133 133 133 PHE PHE B . n 
A 1 134 GLN 134 134 134 GLN GLN B . n 
A 1 135 LEU 135 135 135 LEU LEU B . n 
A 1 136 THR 136 136 136 THR THR B . n 
A 1 137 HIS 137 137 137 HIS HIS B . n 
A 1 138 SER 138 138 138 SER SER B . n 
A 1 139 LEU 139 139 139 LEU LEU B . n 
A 1 140 GLY 140 140 140 GLY GLY B . n 
A 1 141 GLY 141 141 141 GLY GLY B . n 
A 1 142 GLY 142 142 142 GLY GLY B . n 
A 1 143 THR 143 143 143 THR THR B . n 
A 1 144 GLY 144 144 144 GLY GLY B . n 
A 1 145 SER 145 145 145 SER SER B . n 
A 1 146 GLY 146 146 146 GLY GLY B . n 
A 1 147 MET 147 147 147 MET MET B . n 
A 1 148 GLY 148 148 148 GLY GLY B . n 
A 1 149 THR 149 149 149 THR THR B . n 
A 1 150 LEU 150 150 150 LEU LEU B . n 
A 1 151 LEU 151 151 151 LEU LEU B . n 
A 1 152 ILE 152 152 152 ILE ILE B . n 
A 1 153 SER 153 153 153 SER SER B . n 
A 1 154 LYS 154 154 154 LYS LYS B . n 
A 1 155 ILE 155 155 155 ILE ILE B . n 
A 1 156 ARG 156 156 156 ARG ARG B . n 
A 1 157 GLU 157 157 157 GLU GLU B . n 
A 1 158 GLU 158 158 158 GLU GLU B . n 
A 1 159 TYR 159 159 159 TYR TYR B . n 
A 1 160 PRO 160 160 160 PRO PRO B . n 
A 1 161 ASP 161 161 161 ASP ASP B . n 
A 1 162 ARG 162 162 162 ARG ARG B . n 
A 1 163 ILE 163 163 163 ILE ILE B . n 
A 1 164 MET 164 164 164 MET MET B . n 
A 1 165 ASN 165 165 165 ASN ASN B . n 
A 1 166 THR 166 166 166 THR THR B . n 
A 1 167 PHE 167 167 167 PHE PHE B . n 
A 1 168 SER 168 168 168 SER SER B . n 
A 1 169 VAL 169 169 169 VAL VAL B . n 
A 1 170 VAL 170 170 170 VAL VAL B . n 
A 1 171 PRO 171 171 171 PRO PRO B . n 
A 1 172 SER 172 172 172 SER SER B . n 
A 1 173 PRO 173 173 173 PRO PRO B . n 
A 1 174 LYS 174 174 174 LYS LYS B . n 
A 1 175 VAL 175 175 175 VAL VAL B . n 
A 1 176 SER 176 176 176 SER SER B . n 
A 1 177 ASP 177 177 177 ASP ASP B . n 
A 1 178 THR 178 178 178 THR THR B . n 
A 1 179 VAL 179 179 179 VAL VAL B . n 
A 1 180 VAL 180 180 180 VAL VAL B . n 
A 1 181 GLU 181 181 181 GLU GLU B . n 
A 1 182 PRO 182 182 182 PRO PRO B . n 
A 1 183 TYR 183 183 183 TYR TYR B . n 
A 1 184 ASN 184 184 184 ASN ASN B . n 
A 1 185 ALA 185 185 185 ALA ALA B . n 
A 1 186 THR 186 186 186 THR THR B . n 
A 1 187 LEU 187 187 187 LEU LEU B . n 
A 1 188 SER 188 188 188 SER SER B . n 
A 1 189 VAL 189 189 189 VAL VAL B . n 
A 1 190 HIS 190 190 190 HIS HIS B . n 
A 1 191 GLN 191 191 191 GLN GLN B . n 
A 1 192 LEU 192 192 192 LEU LEU B . n 
A 1 193 VAL 193 193 193 VAL VAL B . n 
A 1 194 GLU 194 194 194 GLU GLU B . n 
A 1 195 ASN 195 195 195 ASN ASN B . n 
A 1 196 THR 196 196 196 THR THR B . n 
A 1 197 ASP 197 197 197 ASP ASP B . n 
A 1 198 GLU 198 198 198 GLU GLU B . n 
A 1 199 THR 199 199 199 THR THR B . n 
A 1 200 TYR 200 200 200 TYR TYR B . n 
A 1 201 CYS 201 201 201 CYS CYS B . n 
A 1 202 ILE 202 202 202 ILE ILE B . n 
A 1 203 ASP 203 203 203 ASP ASP B . n 
A 1 204 ASN 204 204 204 ASN ASN B . n 
A 1 205 GLU 205 205 205 GLU GLU B . n 
A 1 206 ALA 206 206 206 ALA ALA B . n 
A 1 207 LEU 207 207 207 LEU LEU B . n 
A 1 208 TYR 208 208 208 TYR TYR B . n 
A 1 209 ASP 209 209 209 ASP ASP B . n 
A 1 210 ILE 210 210 210 ILE ILE B . n 
A 1 211 CYS 211 211 211 CYS CYS B . n 
A 1 212 PHE 212 212 212 PHE PHE B . n 
A 1 213 ARG 213 213 213 ARG ARG B . n 
A 1 214 THR 214 214 214 THR THR B . n 
A 1 215 LEU 215 215 215 LEU LEU B . n 
A 1 216 LYS 216 216 216 LYS LYS B . n 
A 1 217 LEU 217 217 217 LEU LEU B . n 
A 1 218 THR 218 218 218 THR THR B . n 
A 1 219 THR 219 219 219 THR THR B . n 
A 1 220 PRO 220 220 220 PRO PRO B . n 
A 1 221 THR 221 221 221 THR THR B . n 
A 1 222 TYR 222 222 222 TYR TYR B . n 
A 1 223 GLY 223 223 223 GLY GLY B . n 
A 1 224 ASP 224 224 224 ASP ASP B . n 
A 1 225 LEU 225 225 225 LEU LEU B . n 
A 1 226 ASN 226 226 226 ASN ASN B . n 
A 1 227 HIS 227 227 227 HIS HIS B . n 
A 1 228 LEU 228 228 228 LEU LEU B . n 
A 1 229 VAL 229 229 229 VAL VAL B . n 
A 1 230 SER 230 230 230 SER SER B . n 
A 1 231 ALA 231 231 231 ALA ALA B . n 
A 1 232 THR 232 232 232 THR THR B . n 
A 1 233 MET 233 233 233 MET MET B . n 
A 1 234 SER 234 234 234 SER SER B . n 
A 1 235 GLY 235 235 235 GLY GLY B . n 
A 1 236 VAL 236 236 236 VAL VAL B . n 
A 1 237 THR 237 237 237 THR THR B . n 
A 1 238 THR 238 238 238 THR THR B . n 
A 1 239 CYS 239 239 239 CYS CYS B . n 
A 1 240 LEU 240 240 240 LEU LEU B . n 
A 1 241 ARG 241 241 241 ARG ARG B . n 
A 1 242 PHE 242 242 242 PHE PHE B . n 
A 1 243 PRO 243 243 243 PRO PRO B . n 
A 1 244 GLY 244 244 244 GLY GLY B . n 
A 1 245 GLN 245 245 245 GLN GLN B . n 
A 1 246 LEU 246 246 246 LEU LEU B . n 
A 1 247 ASN 247 247 247 ASN ASN B . n 
A 1 248 ALA 248 248 248 ALA ALA B . n 
A 1 249 ASP 249 249 249 ASP ASP B . n 
A 1 250 LEU 250 250 250 LEU LEU B . n 
A 1 251 ARG 251 251 251 ARG ARG B . n 
A 1 252 LYS 252 252 252 LYS LYS B . n 
A 1 253 LEU 253 253 253 LEU LEU B . n 
A 1 254 ALA 254 254 254 ALA ALA B . n 
A 1 255 VAL 255 255 255 VAL VAL B . n 
A 1 256 ASN 256 256 256 ASN ASN B . n 
A 1 257 MET 257 257 257 MET MET B . n 
A 1 258 VAL 258 258 258 VAL VAL B . n 
A 1 259 PRO 259 259 259 PRO PRO B . n 
A 1 260 PHE 260 260 260 PHE PHE B . n 
A 1 261 PRO 261 261 261 PRO PRO B . n 
A 1 262 ARG 262 262 262 ARG ARG B . n 
A 1 263 LEU 263 263 263 LEU LEU B . n 
A 1 264 HIS 264 264 264 HIS HIS B . n 
A 1 265 PHE 265 265 265 PHE PHE B . n 
A 1 266 PHE 266 266 266 PHE PHE B . n 
A 1 267 MET 267 267 267 MET MET B . n 
A 1 268 PRO 268 268 268 PRO PRO B . n 
A 1 269 GLY 269 269 269 GLY GLY B . n 
A 1 270 PHE 270 270 270 PHE PHE B . n 
A 1 271 ALA 271 271 271 ALA ALA B . n 
A 1 272 PRO 272 272 272 PRO PRO B . n 
A 1 273 LEU 273 273 273 LEU LEU B . n 
A 1 274 THR 274 274 274 THR THR B . n 
A 1 275 SER 275 275 275 SER SER B . n 
A 1 276 ARG 276 276 276 ARG ARG B . n 
A 1 277 GLY 277 277 277 GLY GLY B . n 
A 1 278 SER 278 278 278 SER SER B . n 
A 1 279 GLN 279 279 279 GLN GLN B . n 
A 1 280 GLN 280 280 280 GLN GLN B . n 
A 1 281 TYR 281 281 281 TYR TYR B . n 
A 1 282 ARG 282 282 282 ARG ARG B . n 
A 1 283 ALA 283 283 283 ALA ALA B . n 
A 1 284 LEU 284 284 284 LEU LEU B . n 
A 1 285 THR 285 285 285 THR THR B . n 
A 1 286 VAL 286 286 286 VAL VAL B . n 
A 1 287 PRO 287 287 287 PRO PRO B . n 
A 1 288 GLU 288 288 288 GLU GLU B . n 
A 1 289 LEU 289 289 289 LEU LEU B . n 
A 1 290 THR 290 290 290 THR THR B . n 
A 1 291 GLN 291 291 291 GLN GLN B . n 
A 1 292 GLN 292 292 292 GLN GLN B . n 
A 1 293 VAL 293 293 293 VAL VAL B . n 
A 1 294 PHE 294 294 294 PHE PHE B . n 
A 1 295 ASP 295 295 295 ASP ASP B . n 
A 1 296 ALA 296 296 296 ALA ALA B . n 
A 1 297 LYS 297 297 297 LYS LYS B . n 
A 1 298 ASN 298 298 298 ASN ASN B . n 
A 1 299 MET 299 299 299 MET MET B . n 
A 1 300 MET 300 300 300 MET MET B . n 
A 1 301 ALA 301 301 301 ALA ALA B . n 
A 1 302 ALA 302 302 302 ALA ALA B . n 
A 1 303 CYS 303 303 303 CYS CYS B . n 
A 1 304 ASP 304 304 304 ASP ASP B . n 
A 1 305 PRO 305 305 305 PRO PRO B . n 
A 1 306 ARG 306 306 306 ARG ARG B . n 
A 1 307 HIS 307 307 307 HIS HIS B . n 
A 1 308 GLY 308 308 308 GLY GLY B . n 
A 1 309 ARG 309 309 309 ARG ARG B . n 
A 1 310 TYR 310 310 310 TYR TYR B . n 
A 1 311 LEU 311 311 311 LEU LEU B . n 
A 1 312 THR 312 312 312 THR THR B . n 
A 1 313 VAL 313 313 313 VAL VAL B . n 
A 1 314 ALA 314 314 314 ALA ALA B . n 
A 1 315 ALA 315 315 315 ALA ALA B . n 
A 1 316 VAL 316 316 316 VAL VAL B . n 
A 1 317 PHE 317 317 317 PHE PHE B . n 
A 1 318 ARG 318 318 318 ARG ARG B . n 
A 1 319 GLY 319 319 319 GLY GLY B . n 
A 1 320 ARG 320 320 320 ARG ARG B . n 
A 1 321 MET 321 321 321 MET MET B . n 
A 1 322 SER 322 322 322 SER SER B . n 
A 1 323 MET 323 323 323 MET MET B . n 
A 1 324 LYS 324 324 324 LYS LYS B . n 
A 1 325 GLU 325 325 325 GLU GLU B . n 
A 1 326 VAL 326 326 326 VAL VAL B . n 
A 1 327 ASP 327 327 327 ASP ASP B . n 
A 1 328 GLU 328 328 328 GLU GLU B . n 
A 1 329 GLN 329 329 329 GLN GLN B . n 
A 1 330 MET 330 330 330 MET MET B . n 
A 1 331 LEU 331 331 331 LEU LEU B . n 
A 1 332 ASN 332 332 332 ASN ASN B . n 
A 1 333 VAL 333 333 333 VAL VAL B . n 
A 1 334 GLN 334 334 334 GLN GLN B . n 
A 1 335 ASN 335 335 335 ASN ASN B . n 
A 1 336 LYS 336 336 336 LYS LYS B . n 
A 1 337 ASN 337 337 337 ASN ASN B . n 
A 1 338 SER 338 338 338 SER SER B . n 
A 1 339 SER 339 339 339 SER SER B . n 
A 1 340 TYR 340 340 340 TYR TYR B . n 
A 1 341 PHE 341 341 341 PHE PHE B . n 
A 1 342 VAL 342 342 342 VAL VAL B . n 
A 1 343 GLU 343 343 343 GLU GLU B . n 
A 1 344 TRP 344 344 344 TRP TRP B . n 
A 1 345 ILE 345 345 345 ILE ILE B . n 
A 1 346 PRO 346 346 346 PRO PRO B . n 
A 1 347 ASN 347 347 347 ASN ASN B . n 
A 1 348 ASN 348 348 348 ASN ASN B . n 
A 1 349 VAL 349 349 349 VAL VAL B . n 
A 1 350 LYS 350 350 350 LYS LYS B . n 
A 1 351 THR 351 351 351 THR THR B . n 
A 1 352 ALA 352 352 352 ALA ALA B . n 
A 1 353 VAL 353 353 353 VAL VAL B . n 
A 1 354 CYS 354 354 354 CYS CYS B . n 
A 1 355 ASP 355 355 355 ASP ASP B . n 
A 1 356 ILE 356 356 356 ILE ILE B . n 
A 1 357 PRO 357 357 357 PRO PRO B . n 
A 1 358 PRO 358 358 358 PRO PRO B . n 
A 1 359 ARG 359 359 359 ARG ARG B . n 
A 1 360 GLY 360 360 360 GLY GLY B . n 
A 1 361 LEU 361 361 361 LEU LEU B . n 
A 1 362 LYS 362 362 362 LYS LYS B . n 
A 1 363 MET 363 363 363 MET MET B . n 
A 1 364 ALA 364 364 364 ALA ALA B . n 
A 1 365 VAL 365 365 365 VAL VAL B . n 
A 1 366 THR 366 366 366 THR THR B . n 
A 1 367 PHE 367 367 367 PHE PHE B . n 
A 1 368 ILE 368 368 368 ILE ILE B . n 
A 1 369 GLY 369 369 369 GLY GLY B . n 
A 1 370 ASN 370 370 370 ASN ASN B . n 
A 1 371 SER 371 371 371 SER SER B . n 
A 1 372 THR 372 372 372 THR THR B . n 
A 1 373 ALA 373 373 373 ALA ALA B . n 
A 1 374 ILE 374 374 374 ILE ILE B . n 
A 1 375 GLN 375 375 375 GLN GLN B . n 
A 1 376 GLU 376 376 376 GLU GLU B . n 
A 1 377 LEU 377 377 377 LEU LEU B . n 
A 1 378 PHE 378 378 378 PHE PHE B . n 
A 1 379 LYS 379 379 379 LYS LYS B . n 
A 1 380 ARG 380 380 380 ARG ARG B . n 
A 1 381 ILE 381 381 381 ILE ILE B . n 
A 1 382 SER 382 382 382 SER SER B . n 
A 1 383 GLU 383 383 383 GLU GLU B . n 
A 1 384 GLN 384 384 384 GLN GLN B . n 
A 1 385 PHE 385 385 385 PHE PHE B . n 
A 1 386 THR 386 386 386 THR THR B . n 
A 1 387 ALA 387 387 387 ALA ALA B . n 
A 1 388 MET 388 388 388 MET MET B . n 
A 1 389 PHE 389 389 389 PHE PHE B . n 
A 1 390 ARG 390 390 390 ARG ARG B . n 
A 1 391 ARG 391 391 391 ARG ARG B . n 
A 1 392 LYS 392 392 392 LYS LYS B . n 
A 1 393 ALA 393 393 393 ALA ALA B . n 
A 1 394 PHE 394 394 394 PHE PHE B . n 
A 1 395 LEU 395 395 395 LEU LEU B . n 
A 1 396 HIS 396 396 396 HIS HIS B . n 
A 1 397 TRP 397 397 397 TRP TRP B . n 
A 1 398 TYR 398 398 398 TYR TYR B . n 
A 1 399 THR 399 399 399 THR THR B . n 
A 1 400 GLY 400 400 400 GLY GLY B . n 
A 1 401 GLU 401 401 401 GLU GLU B . n 
A 1 402 GLY 402 402 402 GLY GLY B . n 
A 1 403 MET 403 403 403 MET MET B . n 
A 1 404 ASP 404 404 404 ASP ASP B . n 
A 1 405 GLU 405 405 405 GLU GLU B . n 
A 1 406 MET 406 406 406 MET MET B . n 
A 1 407 GLU 407 407 407 GLU GLU B . n 
A 1 408 PHE 408 408 408 PHE PHE B . n 
A 1 409 THR 409 409 409 THR THR B . n 
A 1 410 GLU 410 410 410 GLU GLU B . n 
A 1 411 ALA 411 411 411 ALA ALA B . n 
A 1 412 GLU 412 412 412 GLU GLU B . n 
A 1 413 SER 413 413 413 SER SER B . n 
A 1 414 ASN 414 414 414 ASN ASN B . n 
A 1 415 MET 415 415 415 MET MET B . n 
A 1 416 ASN 416 416 416 ASN ASN B . n 
A 1 417 ASP 417 417 417 ASP ASP B . n 
A 1 418 LEU 418 418 418 LEU LEU B . n 
A 1 419 VAL 419 419 419 VAL VAL B . n 
A 1 420 SER 420 420 420 SER SER B . n 
A 1 421 GLU 421 421 421 GLU GLU B . n 
A 1 422 TYR 422 422 422 TYR TYR B . n 
A 1 423 GLN 423 423 423 GLN GLN B . n 
A 1 424 GLN 424 424 424 GLN GLN B . n 
A 1 425 TYR 425 425 425 TYR TYR B . n 
A 1 426 GLN 426 426 426 GLN GLN B . n 
A 1 427 ASP 427 427 427 ASP ASP B . n 
A 1 428 ALA 428 428 428 ALA ALA B . n 
A 1 429 THR 429 429 429 THR THR B . n 
A 1 430 ALA 430 430 ?   ?   ?   B . n 
A 1 431 GLU 431 431 ?   ?   ?   B . n 
A 1 432 GLU 432 432 ?   ?   ?   B . n 
A 1 433 GLU 433 433 ?   ?   ?   B . n 
A 1 434 GLU 434 434 ?   ?   ?   B . n 
A 1 435 ASP 435 435 ?   ?   ?   B . n 
A 1 436 PHE 436 436 ?   ?   ?   B . n 
A 1 437 GLY 437 437 ?   ?   ?   B . n 
A 1 438 GLU 438 438 ?   ?   ?   B . n 
A 1 439 GLU 439 439 ?   ?   ?   B . n 
A 1 440 ALA 440 440 ?   ?   ?   B . n 
A 1 441 GLU 441 441 ?   ?   ?   B . n 
A 1 442 GLU 442 442 ?   ?   ?   B . n 
A 1 443 GLU 443 443 ?   ?   ?   B . n 
A 1 444 ALA 444 444 ?   ?   ?   B . n 
B 1 1   MET 1   1   1   MET MET E . n 
B 1 2   ARG 2   2   2   ARG ARG E . n 
B 1 3   GLU 3   3   3   GLU GLU E . n 
B 1 4   ILE 4   4   4   ILE ILE E . n 
B 1 5   VAL 5   5   5   VAL VAL E . n 
B 1 6   HIS 6   6   6   HIS HIS E . n 
B 1 7   ILE 7   7   7   ILE ILE E . n 
B 1 8   GLN 8   8   8   GLN GLN E . n 
B 1 9   ALA 9   9   9   ALA ALA E . n 
B 1 10  GLY 10  10  10  GLY GLY E . n 
B 1 11  GLN 11  11  11  GLN GLN E . n 
B 1 12  CYS 12  12  12  CYS CYS E . n 
B 1 13  GLY 13  13  13  GLY GLY E . n 
B 1 14  ASN 14  14  14  ASN ASN E . n 
B 1 15  GLN 15  15  15  GLN GLN E . n 
B 1 16  ILE 16  16  16  ILE ILE E . n 
B 1 17  GLY 17  17  17  GLY GLY E . n 
B 1 18  ALA 18  18  18  ALA ALA E . n 
B 1 19  LYS 19  19  19  LYS LYS E . n 
B 1 20  PHE 20  20  20  PHE PHE E . n 
B 1 21  TRP 21  21  21  TRP TRP E . n 
B 1 22  GLU 22  22  22  GLU GLU E . n 
B 1 23  VAL 23  23  23  VAL VAL E . n 
B 1 24  ILE 24  24  24  ILE ILE E . n 
B 1 25  SER 25  25  25  SER SER E . n 
B 1 26  ASP 26  26  26  ASP ASP E . n 
B 1 27  GLU 27  27  27  GLU GLU E . n 
B 1 28  HIS 28  28  28  HIS HIS E . n 
B 1 29  GLY 29  29  29  GLY GLY E . n 
B 1 30  ILE 30  30  30  ILE ILE E . n 
B 1 31  ASP 31  31  31  ASP ASP E . n 
B 1 32  PRO 32  32  32  PRO PRO E . n 
B 1 33  THR 33  33  33  THR THR E . n 
B 1 34  GLY 34  34  34  GLY GLY E . n 
B 1 35  THR 35  35  35  THR THR E . n 
B 1 36  TYR 36  36  36  TYR TYR E . n 
B 1 37  HIS 37  37  37  HIS HIS E . n 
B 1 38  GLY 38  38  38  GLY GLY E . n 
B 1 39  ASP 39  39  39  ASP ASP E . n 
B 1 40  SER 40  40  40  SER SER E . n 
B 1 41  ASP 41  41  41  ASP ASP E . n 
B 1 42  LEU 42  42  42  LEU LEU E . n 
B 1 43  GLN 43  43  43  GLN GLN E . n 
B 1 44  LEU 44  44  44  LEU LEU E . n 
B 1 45  ASP 45  45  45  ASP ASP E . n 
B 1 46  ARG 46  46  46  ARG ARG E . n 
B 1 47  ILE 47  47  47  ILE ILE E . n 
B 1 48  SER 48  48  48  SER SER E . n 
B 1 49  VAL 49  49  49  VAL VAL E . n 
B 1 50  TYR 50  50  50  TYR TYR E . n 
B 1 51  TYR 51  51  51  TYR TYR E . n 
B 1 52  ASN 52  52  52  ASN ASN E . n 
B 1 53  GLU 53  53  53  GLU GLU E . n 
B 1 54  ALA 54  54  54  ALA ALA E . n 
B 1 55  THR 55  55  55  THR THR E . n 
B 1 56  GLY 56  56  56  GLY GLY E . n 
B 1 57  GLY 57  57  57  GLY GLY E . n 
B 1 58  LYS 58  58  58  LYS LYS E . n 
B 1 59  TYR 59  59  59  TYR TYR E . n 
B 1 60  VAL 60  60  60  VAL VAL E . n 
B 1 61  PRO 61  61  61  PRO PRO E . n 
B 1 62  ARG 62  62  62  ARG ARG E . n 
B 1 63  ALA 63  63  63  ALA ALA E . n 
B 1 64  ILE 64  64  64  ILE ILE E . n 
B 1 65  LEU 65  65  65  LEU LEU E . n 
B 1 66  VAL 66  66  66  VAL VAL E . n 
B 1 67  ASP 67  67  67  ASP ASP E . n 
B 1 68  LEU 68  68  68  LEU LEU E . n 
B 1 69  GLU 69  69  69  GLU GLU E . n 
B 1 70  PRO 70  70  70  PRO PRO E . n 
B 1 71  GLY 71  71  71  GLY GLY E . n 
B 1 72  THR 72  72  72  THR THR E . n 
B 1 73  MET 73  73  73  MET MET E . n 
B 1 74  ASP 74  74  74  ASP ASP E . n 
B 1 75  SER 75  75  75  SER SER E . n 
B 1 76  VAL 76  76  76  VAL VAL E . n 
B 1 77  ARG 77  77  77  ARG ARG E . n 
B 1 78  SER 78  78  78  SER SER E . n 
B 1 79  GLY 79  79  79  GLY GLY E . n 
B 1 80  PRO 80  80  80  PRO PRO E . n 
B 1 81  PHE 81  81  81  PHE PHE E . n 
B 1 82  GLY 82  82  82  GLY GLY E . n 
B 1 83  GLN 83  83  83  GLN GLN E . n 
B 1 84  ILE 84  84  84  ILE ILE E . n 
B 1 85  PHE 85  85  85  PHE PHE E . n 
B 1 86  ARG 86  86  86  ARG ARG E . n 
B 1 87  PRO 87  87  87  PRO PRO E . n 
B 1 88  ASP 88  88  88  ASP ASP E . n 
B 1 89  ASN 89  89  89  ASN ASN E . n 
B 1 90  PHE 90  90  90  PHE PHE E . n 
B 1 91  VAL 91  91  91  VAL VAL E . n 
B 1 92  PHE 92  92  92  PHE PHE E . n 
B 1 93  GLY 93  93  93  GLY GLY E . n 
B 1 94  GLN 94  94  94  GLN GLN E . n 
B 1 95  SER 95  95  95  SER SER E . n 
B 1 96  GLY 96  96  96  GLY GLY E . n 
B 1 97  ALA 97  97  97  ALA ALA E . n 
B 1 98  GLY 98  98  98  GLY GLY E . n 
B 1 99  ASN 99  99  99  ASN ASN E . n 
B 1 100 ASN 100 100 100 ASN ASN E . n 
B 1 101 TRP 101 101 101 TRP TRP E . n 
B 1 102 ALA 102 102 102 ALA ALA E . n 
B 1 103 LYS 103 103 103 LYS LYS E . n 
B 1 104 GLY 104 104 104 GLY GLY E . n 
B 1 105 HIS 105 105 105 HIS HIS E . n 
B 1 106 TYR 106 106 106 TYR TYR E . n 
B 1 107 THR 107 107 107 THR THR E . n 
B 1 108 GLU 108 108 108 GLU GLU E . n 
B 1 109 GLY 109 109 109 GLY GLY E . n 
B 1 110 ALA 110 110 110 ALA ALA E . n 
B 1 111 GLU 111 111 111 GLU GLU E . n 
B 1 112 LEU 112 112 112 LEU LEU E . n 
B 1 113 VAL 113 113 113 VAL VAL E . n 
B 1 114 ASP 114 114 114 ASP ASP E . n 
B 1 115 SER 115 115 115 SER SER E . n 
B 1 116 VAL 116 116 116 VAL VAL E . n 
B 1 117 LEU 117 117 117 LEU LEU E . n 
B 1 118 ASP 118 118 118 ASP ASP E . n 
B 1 119 VAL 119 119 119 VAL VAL E . n 
B 1 120 VAL 120 120 120 VAL VAL E . n 
B 1 121 ARG 121 121 121 ARG ARG E . n 
B 1 122 LYS 122 122 122 LYS LYS E . n 
B 1 123 GLU 123 123 123 GLU GLU E . n 
B 1 124 ALA 124 124 124 ALA ALA E . n 
B 1 125 GLU 125 125 125 GLU GLU E . n 
B 1 126 SER 126 126 126 SER SER E . n 
B 1 127 CYS 127 127 127 CYS CYS E . n 
B 1 128 ASP 128 128 128 ASP ASP E . n 
B 1 129 CYS 129 129 129 CYS CYS E . n 
B 1 130 LEU 130 130 130 LEU LEU E . n 
B 1 131 GLN 131 131 131 GLN GLN E . n 
B 1 132 GLY 132 132 132 GLY GLY E . n 
B 1 133 PHE 133 133 133 PHE PHE E . n 
B 1 134 GLN 134 134 134 GLN GLN E . n 
B 1 135 LEU 135 135 135 LEU LEU E . n 
B 1 136 THR 136 136 136 THR THR E . n 
B 1 137 HIS 137 137 137 HIS HIS E . n 
B 1 138 SER 138 138 138 SER SER E . n 
B 1 139 LEU 139 139 139 LEU LEU E . n 
B 1 140 GLY 140 140 140 GLY GLY E . n 
B 1 141 GLY 141 141 141 GLY GLY E . n 
B 1 142 GLY 142 142 142 GLY GLY E . n 
B 1 143 THR 143 143 143 THR THR E . n 
B 1 144 GLY 144 144 144 GLY GLY E . n 
B 1 145 SER 145 145 145 SER SER E . n 
B 1 146 GLY 146 146 146 GLY GLY E . n 
B 1 147 MET 147 147 147 MET MET E . n 
B 1 148 GLY 148 148 148 GLY GLY E . n 
B 1 149 THR 149 149 149 THR THR E . n 
B 1 150 LEU 150 150 150 LEU LEU E . n 
B 1 151 LEU 151 151 151 LEU LEU E . n 
B 1 152 ILE 152 152 152 ILE ILE E . n 
B 1 153 SER 153 153 153 SER SER E . n 
B 1 154 LYS 154 154 154 LYS LYS E . n 
B 1 155 ILE 155 155 155 ILE ILE E . n 
B 1 156 ARG 156 156 156 ARG ARG E . n 
B 1 157 GLU 157 157 157 GLU GLU E . n 
B 1 158 GLU 158 158 158 GLU GLU E . n 
B 1 159 TYR 159 159 159 TYR TYR E . n 
B 1 160 PRO 160 160 160 PRO PRO E . n 
B 1 161 ASP 161 161 161 ASP ASP E . n 
B 1 162 ARG 162 162 162 ARG ARG E . n 
B 1 163 ILE 163 163 163 ILE ILE E . n 
B 1 164 MET 164 164 164 MET MET E . n 
B 1 165 ASN 165 165 165 ASN ASN E . n 
B 1 166 THR 166 166 166 THR THR E . n 
B 1 167 PHE 167 167 167 PHE PHE E . n 
B 1 168 SER 168 168 168 SER SER E . n 
B 1 169 VAL 169 169 169 VAL VAL E . n 
B 1 170 VAL 170 170 170 VAL VAL E . n 
B 1 171 PRO 171 171 171 PRO PRO E . n 
B 1 172 SER 172 172 172 SER SER E . n 
B 1 173 PRO 173 173 173 PRO PRO E . n 
B 1 174 LYS 174 174 174 LYS LYS E . n 
B 1 175 VAL 175 175 175 VAL VAL E . n 
B 1 176 SER 176 176 176 SER SER E . n 
B 1 177 ASP 177 177 177 ASP ASP E . n 
B 1 178 THR 178 178 178 THR THR E . n 
B 1 179 VAL 179 179 179 VAL VAL E . n 
B 1 180 VAL 180 180 180 VAL VAL E . n 
B 1 181 GLU 181 181 181 GLU GLU E . n 
B 1 182 PRO 182 182 182 PRO PRO E . n 
B 1 183 TYR 183 183 183 TYR TYR E . n 
B 1 184 ASN 184 184 184 ASN ASN E . n 
B 1 185 ALA 185 185 185 ALA ALA E . n 
B 1 186 THR 186 186 186 THR THR E . n 
B 1 187 LEU 187 187 187 LEU LEU E . n 
B 1 188 SER 188 188 188 SER SER E . n 
B 1 189 VAL 189 189 189 VAL VAL E . n 
B 1 190 HIS 190 190 190 HIS HIS E . n 
B 1 191 GLN 191 191 191 GLN GLN E . n 
B 1 192 LEU 192 192 192 LEU LEU E . n 
B 1 193 VAL 193 193 193 VAL VAL E . n 
B 1 194 GLU 194 194 194 GLU GLU E . n 
B 1 195 ASN 195 195 195 ASN ASN E . n 
B 1 196 THR 196 196 196 THR THR E . n 
B 1 197 ASP 197 197 197 ASP ASP E . n 
B 1 198 GLU 198 198 198 GLU GLU E . n 
B 1 199 THR 199 199 199 THR THR E . n 
B 1 200 TYR 200 200 200 TYR TYR E . n 
B 1 201 CYS 201 201 201 CYS CYS E . n 
B 1 202 ILE 202 202 202 ILE ILE E . n 
B 1 203 ASP 203 203 203 ASP ASP E . n 
B 1 204 ASN 204 204 204 ASN ASN E . n 
B 1 205 GLU 205 205 205 GLU GLU E . n 
B 1 206 ALA 206 206 206 ALA ALA E . n 
B 1 207 LEU 207 207 207 LEU LEU E . n 
B 1 208 TYR 208 208 208 TYR TYR E . n 
B 1 209 ASP 209 209 209 ASP ASP E . n 
B 1 210 ILE 210 210 210 ILE ILE E . n 
B 1 211 CYS 211 211 211 CYS CYS E . n 
B 1 212 PHE 212 212 212 PHE PHE E . n 
B 1 213 ARG 213 213 213 ARG ARG E . n 
B 1 214 THR 214 214 214 THR THR E . n 
B 1 215 LEU 215 215 215 LEU LEU E . n 
B 1 216 LYS 216 216 216 LYS LYS E . n 
B 1 217 LEU 217 217 217 LEU LEU E . n 
B 1 218 THR 218 218 218 THR THR E . n 
B 1 219 THR 219 219 219 THR THR E . n 
B 1 220 PRO 220 220 220 PRO PRO E . n 
B 1 221 THR 221 221 221 THR THR E . n 
B 1 222 TYR 222 222 222 TYR TYR E . n 
B 1 223 GLY 223 223 223 GLY GLY E . n 
B 1 224 ASP 224 224 224 ASP ASP E . n 
B 1 225 LEU 225 225 225 LEU LEU E . n 
B 1 226 ASN 226 226 226 ASN ASN E . n 
B 1 227 HIS 227 227 227 HIS HIS E . n 
B 1 228 LEU 228 228 228 LEU LEU E . n 
B 1 229 VAL 229 229 229 VAL VAL E . n 
B 1 230 SER 230 230 230 SER SER E . n 
B 1 231 ALA 231 231 231 ALA ALA E . n 
B 1 232 THR 232 232 232 THR THR E . n 
B 1 233 MET 233 233 233 MET MET E . n 
B 1 234 SER 234 234 234 SER SER E . n 
B 1 235 GLY 235 235 235 GLY GLY E . n 
B 1 236 VAL 236 236 236 VAL VAL E . n 
B 1 237 THR 237 237 237 THR THR E . n 
B 1 238 THR 238 238 238 THR THR E . n 
B 1 239 CYS 239 239 239 CYS CYS E . n 
B 1 240 LEU 240 240 240 LEU LEU E . n 
B 1 241 ARG 241 241 241 ARG ARG E . n 
B 1 242 PHE 242 242 242 PHE PHE E . n 
B 1 243 PRO 243 243 243 PRO PRO E . n 
B 1 244 GLY 244 244 244 GLY GLY E . n 
B 1 245 GLN 245 245 245 GLN GLN E . n 
B 1 246 LEU 246 246 246 LEU LEU E . n 
B 1 247 ASN 247 247 247 ASN ASN E . n 
B 1 248 ALA 248 248 248 ALA ALA E . n 
B 1 249 ASP 249 249 249 ASP ASP E . n 
B 1 250 LEU 250 250 250 LEU LEU E . n 
B 1 251 ARG 251 251 251 ARG ARG E . n 
B 1 252 LYS 252 252 252 LYS LYS E . n 
B 1 253 LEU 253 253 253 LEU LEU E . n 
B 1 254 ALA 254 254 254 ALA ALA E . n 
B 1 255 VAL 255 255 255 VAL VAL E . n 
B 1 256 ASN 256 256 256 ASN ASN E . n 
B 1 257 MET 257 257 257 MET MET E . n 
B 1 258 VAL 258 258 258 VAL VAL E . n 
B 1 259 PRO 259 259 259 PRO PRO E . n 
B 1 260 PHE 260 260 260 PHE PHE E . n 
B 1 261 PRO 261 261 261 PRO PRO E . n 
B 1 262 ARG 262 262 262 ARG ARG E . n 
B 1 263 LEU 263 263 263 LEU LEU E . n 
B 1 264 HIS 264 264 264 HIS HIS E . n 
B 1 265 PHE 265 265 265 PHE PHE E . n 
B 1 266 PHE 266 266 266 PHE PHE E . n 
B 1 267 MET 267 267 267 MET MET E . n 
B 1 268 PRO 268 268 268 PRO PRO E . n 
B 1 269 GLY 269 269 269 GLY GLY E . n 
B 1 270 PHE 270 270 270 PHE PHE E . n 
B 1 271 ALA 271 271 271 ALA ALA E . n 
B 1 272 PRO 272 272 272 PRO PRO E . n 
B 1 273 LEU 273 273 273 LEU LEU E . n 
B 1 274 THR 274 274 274 THR THR E . n 
B 1 275 SER 275 275 275 SER SER E . n 
B 1 276 ARG 276 276 276 ARG ARG E . n 
B 1 277 GLY 277 277 277 GLY GLY E . n 
B 1 278 SER 278 278 278 SER SER E . n 
B 1 279 GLN 279 279 279 GLN GLN E . n 
B 1 280 GLN 280 280 280 GLN GLN E . n 
B 1 281 TYR 281 281 281 TYR TYR E . n 
B 1 282 ARG 282 282 282 ARG ARG E . n 
B 1 283 ALA 283 283 283 ALA ALA E . n 
B 1 284 LEU 284 284 284 LEU LEU E . n 
B 1 285 THR 285 285 285 THR THR E . n 
B 1 286 VAL 286 286 286 VAL VAL E . n 
B 1 287 PRO 287 287 287 PRO PRO E . n 
B 1 288 GLU 288 288 288 GLU GLU E . n 
B 1 289 LEU 289 289 289 LEU LEU E . n 
B 1 290 THR 290 290 290 THR THR E . n 
B 1 291 GLN 291 291 291 GLN GLN E . n 
B 1 292 GLN 292 292 292 GLN GLN E . n 
B 1 293 VAL 293 293 293 VAL VAL E . n 
B 1 294 PHE 294 294 294 PHE PHE E . n 
B 1 295 ASP 295 295 295 ASP ASP E . n 
B 1 296 ALA 296 296 296 ALA ALA E . n 
B 1 297 LYS 297 297 297 LYS LYS E . n 
B 1 298 ASN 298 298 298 ASN ASN E . n 
B 1 299 MET 299 299 299 MET MET E . n 
B 1 300 MET 300 300 300 MET MET E . n 
B 1 301 ALA 301 301 301 ALA ALA E . n 
B 1 302 ALA 302 302 302 ALA ALA E . n 
B 1 303 CYS 303 303 303 CYS CYS E . n 
B 1 304 ASP 304 304 304 ASP ASP E . n 
B 1 305 PRO 305 305 305 PRO PRO E . n 
B 1 306 ARG 306 306 306 ARG ARG E . n 
B 1 307 HIS 307 307 307 HIS HIS E . n 
B 1 308 GLY 308 308 308 GLY GLY E . n 
B 1 309 ARG 309 309 309 ARG ARG E . n 
B 1 310 TYR 310 310 310 TYR TYR E . n 
B 1 311 LEU 311 311 311 LEU LEU E . n 
B 1 312 THR 312 312 312 THR THR E . n 
B 1 313 VAL 313 313 313 VAL VAL E . n 
B 1 314 ALA 314 314 314 ALA ALA E . n 
B 1 315 ALA 315 315 315 ALA ALA E . n 
B 1 316 VAL 316 316 316 VAL VAL E . n 
B 1 317 PHE 317 317 317 PHE PHE E . n 
B 1 318 ARG 318 318 318 ARG ARG E . n 
B 1 319 GLY 319 319 319 GLY GLY E . n 
B 1 320 ARG 320 320 320 ARG ARG E . n 
B 1 321 MET 321 321 321 MET MET E . n 
B 1 322 SER 322 322 322 SER SER E . n 
B 1 323 MET 323 323 323 MET MET E . n 
B 1 324 LYS 324 324 324 LYS LYS E . n 
B 1 325 GLU 325 325 325 GLU GLU E . n 
B 1 326 VAL 326 326 326 VAL VAL E . n 
B 1 327 ASP 327 327 327 ASP ASP E . n 
B 1 328 GLU 328 328 328 GLU GLU E . n 
B 1 329 GLN 329 329 329 GLN GLN E . n 
B 1 330 MET 330 330 330 MET MET E . n 
B 1 331 LEU 331 331 331 LEU LEU E . n 
B 1 332 ASN 332 332 332 ASN ASN E . n 
B 1 333 VAL 333 333 333 VAL VAL E . n 
B 1 334 GLN 334 334 334 GLN GLN E . n 
B 1 335 ASN 335 335 335 ASN ASN E . n 
B 1 336 LYS 336 336 336 LYS LYS E . n 
B 1 337 ASN 337 337 337 ASN ASN E . n 
B 1 338 SER 338 338 338 SER SER E . n 
B 1 339 SER 339 339 339 SER SER E . n 
B 1 340 TYR 340 340 340 TYR TYR E . n 
B 1 341 PHE 341 341 341 PHE PHE E . n 
B 1 342 VAL 342 342 342 VAL VAL E . n 
B 1 343 GLU 343 343 343 GLU GLU E . n 
B 1 344 TRP 344 344 344 TRP TRP E . n 
B 1 345 ILE 345 345 345 ILE ILE E . n 
B 1 346 PRO 346 346 346 PRO PRO E . n 
B 1 347 ASN 347 347 347 ASN ASN E . n 
B 1 348 ASN 348 348 348 ASN ASN E . n 
B 1 349 VAL 349 349 349 VAL VAL E . n 
B 1 350 LYS 350 350 350 LYS LYS E . n 
B 1 351 THR 351 351 351 THR THR E . n 
B 1 352 ALA 352 352 352 ALA ALA E . n 
B 1 353 VAL 353 353 353 VAL VAL E . n 
B 1 354 CYS 354 354 354 CYS CYS E . n 
B 1 355 ASP 355 355 355 ASP ASP E . n 
B 1 356 ILE 356 356 356 ILE ILE E . n 
B 1 357 PRO 357 357 357 PRO PRO E . n 
B 1 358 PRO 358 358 358 PRO PRO E . n 
B 1 359 ARG 359 359 359 ARG ARG E . n 
B 1 360 GLY 360 360 360 GLY GLY E . n 
B 1 361 LEU 361 361 361 LEU LEU E . n 
B 1 362 LYS 362 362 362 LYS LYS E . n 
B 1 363 MET 363 363 363 MET MET E . n 
B 1 364 ALA 364 364 364 ALA ALA E . n 
B 1 365 VAL 365 365 365 VAL VAL E . n 
B 1 366 THR 366 366 366 THR THR E . n 
B 1 367 PHE 367 367 367 PHE PHE E . n 
B 1 368 ILE 368 368 368 ILE ILE E . n 
B 1 369 GLY 369 369 369 GLY GLY E . n 
B 1 370 ASN 370 370 370 ASN ASN E . n 
B 1 371 SER 371 371 371 SER SER E . n 
B 1 372 THR 372 372 372 THR THR E . n 
B 1 373 ALA 373 373 373 ALA ALA E . n 
B 1 374 ILE 374 374 374 ILE ILE E . n 
B 1 375 GLN 375 375 375 GLN GLN E . n 
B 1 376 GLU 376 376 376 GLU GLU E . n 
B 1 377 LEU 377 377 377 LEU LEU E . n 
B 1 378 PHE 378 378 378 PHE PHE E . n 
B 1 379 LYS 379 379 379 LYS LYS E . n 
B 1 380 ARG 380 380 380 ARG ARG E . n 
B 1 381 ILE 381 381 381 ILE ILE E . n 
B 1 382 SER 382 382 382 SER SER E . n 
B 1 383 GLU 383 383 383 GLU GLU E . n 
B 1 384 GLN 384 384 384 GLN GLN E . n 
B 1 385 PHE 385 385 385 PHE PHE E . n 
B 1 386 THR 386 386 386 THR THR E . n 
B 1 387 ALA 387 387 387 ALA ALA E . n 
B 1 388 MET 388 388 388 MET MET E . n 
B 1 389 PHE 389 389 389 PHE PHE E . n 
B 1 390 ARG 390 390 390 ARG ARG E . n 
B 1 391 ARG 391 391 391 ARG ARG E . n 
B 1 392 LYS 392 392 392 LYS LYS E . n 
B 1 393 ALA 393 393 393 ALA ALA E . n 
B 1 394 PHE 394 394 394 PHE PHE E . n 
B 1 395 LEU 395 395 395 LEU LEU E . n 
B 1 396 HIS 396 396 396 HIS HIS E . n 
B 1 397 TRP 397 397 397 TRP TRP E . n 
B 1 398 TYR 398 398 398 TYR TYR E . n 
B 1 399 THR 399 399 399 THR THR E . n 
B 1 400 GLY 400 400 400 GLY GLY E . n 
B 1 401 GLU 401 401 401 GLU GLU E . n 
B 1 402 GLY 402 402 402 GLY GLY E . n 
B 1 403 MET 403 403 403 MET MET E . n 
B 1 404 ASP 404 404 404 ASP ASP E . n 
B 1 405 GLU 405 405 405 GLU GLU E . n 
B 1 406 MET 406 406 406 MET MET E . n 
B 1 407 GLU 407 407 407 GLU GLU E . n 
B 1 408 PHE 408 408 408 PHE PHE E . n 
B 1 409 THR 409 409 409 THR THR E . n 
B 1 410 GLU 410 410 410 GLU GLU E . n 
B 1 411 ALA 411 411 411 ALA ALA E . n 
B 1 412 GLU 412 412 412 GLU GLU E . n 
B 1 413 SER 413 413 413 SER SER E . n 
B 1 414 ASN 414 414 414 ASN ASN E . n 
B 1 415 MET 415 415 415 MET MET E . n 
B 1 416 ASN 416 416 416 ASN ASN E . n 
B 1 417 ASP 417 417 417 ASP ASP E . n 
B 1 418 LEU 418 418 418 LEU LEU E . n 
B 1 419 VAL 419 419 419 VAL VAL E . n 
B 1 420 SER 420 420 420 SER SER E . n 
B 1 421 GLU 421 421 421 GLU GLU E . n 
B 1 422 TYR 422 422 422 TYR TYR E . n 
B 1 423 GLN 423 423 423 GLN GLN E . n 
B 1 424 GLN 424 424 424 GLN GLN E . n 
B 1 425 TYR 425 425 425 TYR TYR E . n 
B 1 426 GLN 426 426 426 GLN GLN E . n 
B 1 427 ASP 427 427 427 ASP ASP E . n 
B 1 428 ALA 428 428 428 ALA ALA E . n 
B 1 429 THR 429 429 429 THR THR E . n 
B 1 430 ALA 430 430 ?   ?   ?   E . n 
B 1 431 GLU 431 431 ?   ?   ?   E . n 
B 1 432 GLU 432 432 ?   ?   ?   E . n 
B 1 433 GLU 433 433 ?   ?   ?   E . n 
B 1 434 GLU 434 434 ?   ?   ?   E . n 
B 1 435 ASP 435 435 ?   ?   ?   E . n 
B 1 436 PHE 436 436 ?   ?   ?   E . n 
B 1 437 GLY 437 437 ?   ?   ?   E . n 
B 1 438 GLU 438 438 ?   ?   ?   E . n 
B 1 439 GLU 439 439 ?   ?   ?   E . n 
B 1 440 ALA 440 440 ?   ?   ?   E . n 
B 1 441 GLU 441 441 ?   ?   ?   E . n 
B 1 442 GLU 442 442 ?   ?   ?   E . n 
B 1 443 GLU 443 443 ?   ?   ?   E . n 
B 1 444 ALA 444 444 ?   ?   ?   E . n 
C 2 1   MET 1   1   1   MET MET A . n 
C 2 2   ARG 2   2   2   ARG ARG A . n 
C 2 3   GLU 3   3   3   GLU GLU A . n 
C 2 4   CYS 4   4   4   CYS CYS A . n 
C 2 5   ILE 5   5   5   ILE ILE A . n 
C 2 6   SER 6   6   6   SER SER A . n 
C 2 7   ILE 7   7   7   ILE ILE A . n 
C 2 8   HIS 8   8   8   HIS HIS A . n 
C 2 9   VAL 9   9   9   VAL VAL A . n 
C 2 10  GLY 10  10  10  GLY GLY A . n 
C 2 11  GLN 11  11  11  GLN GLN A . n 
C 2 12  ALA 12  12  12  ALA ALA A . n 
C 2 13  GLY 13  13  13  GLY GLY A . n 
C 2 14  VAL 14  14  14  VAL VAL A . n 
C 2 15  GLN 15  15  15  GLN GLN A . n 
C 2 16  ILE 16  16  16  ILE ILE A . n 
C 2 17  GLY 17  17  17  GLY GLY A . n 
C 2 18  ASN 18  18  18  ASN ASN A . n 
C 2 19  ALA 19  19  19  ALA ALA A . n 
C 2 20  CYS 20  20  20  CYS CYS A . n 
C 2 21  TRP 21  21  21  TRP TRP A . n 
C 2 22  GLU 22  22  22  GLU GLU A . n 
C 2 23  LEU 23  23  23  LEU LEU A . n 
C 2 24  TYR 24  24  24  TYR TYR A . n 
C 2 25  CYS 25  25  25  CYS CYS A . n 
C 2 26  LEU 26  26  26  LEU LEU A . n 
C 2 27  GLU 27  27  27  GLU GLU A . n 
C 2 28  HIS 28  28  28  HIS HIS A . n 
C 2 29  GLY 29  29  29  GLY GLY A . n 
C 2 30  ILE 30  30  30  ILE ILE A . n 
C 2 31  GLN 31  31  31  GLN GLN A . n 
C 2 32  PRO 32  32  32  PRO PRO A . n 
C 2 33  ASP 33  33  33  ASP ASP A . n 
C 2 34  GLY 34  34  34  GLY GLY A . n 
C 2 35  GLN 35  35  35  GLN GLN A . n 
C 2 36  MET 36  36  36  MET MET A . n 
C 2 37  PRO 37  37  37  PRO PRO A . n 
C 2 38  SER 38  38  38  SER SER A . n 
C 2 39  ASP 39  39  ?   ?   ?   A . n 
C 2 40  LYS 40  40  ?   ?   ?   A . n 
C 2 41  THR 41  41  ?   ?   ?   A . n 
C 2 42  ILE 42  42  ?   ?   ?   A . n 
C 2 43  GLY 43  43  43  GLY GLY A . n 
C 2 44  GLY 44  44  44  GLY GLY A . n 
C 2 45  GLY 45  45  45  GLY GLY A . n 
C 2 46  ASP 46  46  46  ASP ASP A . n 
C 2 47  ASP 47  47  47  ASP ASP A . n 
C 2 48  SER 48  48  48  SER SER A . n 
C 2 49  PHE 49  49  49  PHE PHE A . n 
C 2 50  ASN 50  50  50  ASN ASN A . n 
C 2 51  THR 51  51  51  THR THR A . n 
C 2 52  PHE 52  52  52  PHE PHE A . n 
C 2 53  PHE 53  53  53  PHE PHE A . n 
C 2 54  SER 54  54  54  SER SER A . n 
C 2 55  GLU 55  55  55  GLU GLU A . n 
C 2 56  THR 56  56  56  THR THR A . n 
C 2 57  GLY 57  57  57  GLY GLY A . n 
C 2 58  ALA 58  58  58  ALA ALA A . n 
C 2 59  GLY 59  59  59  GLY GLY A . n 
C 2 60  LYS 60  60  60  LYS LYS A . n 
C 2 61  HIS 61  61  61  HIS HIS A . n 
C 2 62  VAL 62  62  62  VAL VAL A . n 
C 2 63  PRO 63  63  63  PRO PRO A . n 
C 2 64  ARG 64  64  64  ARG ARG A . n 
C 2 65  ALA 65  65  65  ALA ALA A . n 
C 2 66  VAL 66  66  66  VAL VAL A . n 
C 2 67  PHE 67  67  67  PHE PHE A . n 
C 2 68  VAL 68  68  68  VAL VAL A . n 
C 2 69  ASP 69  69  69  ASP ASP A . n 
C 2 70  LEU 70  70  70  LEU LEU A . n 
C 2 71  GLU 71  71  71  GLU GLU A . n 
C 2 72  PRO 72  72  72  PRO PRO A . n 
C 2 73  THR 73  73  73  THR THR A . n 
C 2 74  VAL 74  74  74  VAL VAL A . n 
C 2 75  ILE 75  75  75  ILE ILE A . n 
C 2 76  ASP 76  76  76  ASP ASP A . n 
C 2 77  GLU 77  77  77  GLU GLU A . n 
C 2 78  VAL 78  78  78  VAL VAL A . n 
C 2 79  ARG 79  79  79  ARG ARG A . n 
C 2 80  THR 80  80  80  THR THR A . n 
C 2 81  GLY 81  81  81  GLY GLY A . n 
C 2 82  THR 82  82  82  THR THR A . n 
C 2 83  TYR 83  83  83  TYR TYR A . n 
C 2 84  ARG 84  84  84  ARG ARG A . n 
C 2 85  GLN 85  85  85  GLN GLN A . n 
C 2 86  LEU 86  86  86  LEU LEU A . n 
C 2 87  PHE 87  87  87  PHE PHE A . n 
C 2 88  HIS 88  88  88  HIS HIS A . n 
C 2 89  PRO 89  89  89  PRO PRO A . n 
C 2 90  GLU 90  90  90  GLU GLU A . n 
C 2 91  GLN 91  91  91  GLN GLN A . n 
C 2 92  LEU 92  92  92  LEU LEU A . n 
C 2 93  ILE 93  93  93  ILE ILE A . n 
C 2 94  THR 94  94  94  THR THR A . n 
C 2 95  GLY 95  95  95  GLY GLY A . n 
C 2 96  LYS 96  96  96  LYS LYS A . n 
C 2 97  GLU 97  97  97  GLU GLU A . n 
C 2 98  ASP 98  98  98  ASP ASP A . n 
C 2 99  ALA 99  99  99  ALA ALA A . n 
C 2 100 ALA 100 100 100 ALA ALA A . n 
C 2 101 ASN 101 101 101 ASN ASN A . n 
C 2 102 ASN 102 102 102 ASN ASN A . n 
C 2 103 TYR 103 103 103 TYR TYR A . n 
C 2 104 ALA 104 104 104 ALA ALA A . n 
C 2 105 ARG 105 105 105 ARG ARG A . n 
C 2 106 GLY 106 106 106 GLY GLY A . n 
C 2 107 HIS 107 107 107 HIS HIS A . n 
C 2 108 TYR 108 108 108 TYR TYR A . n 
C 2 109 THR 109 109 109 THR THR A . n 
C 2 110 ILE 110 110 110 ILE ILE A . n 
C 2 111 GLY 111 111 111 GLY GLY A . n 
C 2 112 LYS 112 112 112 LYS LYS A . n 
C 2 113 GLU 113 113 113 GLU GLU A . n 
C 2 114 ILE 114 114 114 ILE ILE A . n 
C 2 115 ILE 115 115 115 ILE ILE A . n 
C 2 116 ASP 116 116 116 ASP ASP A . n 
C 2 117 LEU 117 117 117 LEU LEU A . n 
C 2 118 VAL 118 118 118 VAL VAL A . n 
C 2 119 LEU 119 119 119 LEU LEU A . n 
C 2 120 ASP 120 120 120 ASP ASP A . n 
C 2 121 ARG 121 121 121 ARG ARG A . n 
C 2 122 ILE 122 122 122 ILE ILE A . n 
C 2 123 ARG 123 123 123 ARG ARG A . n 
C 2 124 LYS 124 124 124 LYS LYS A . n 
C 2 125 LEU 125 125 125 LEU LEU A . n 
C 2 126 ALA 126 126 126 ALA ALA A . n 
C 2 127 ASP 127 127 127 ASP ASP A . n 
C 2 128 GLN 128 128 128 GLN GLN A . n 
C 2 129 CYS 129 129 129 CYS CYS A . n 
C 2 130 THR 130 130 130 THR THR A . n 
C 2 131 GLY 131 131 131 GLY GLY A . n 
C 2 132 LEU 132 132 132 LEU LEU A . n 
C 2 133 GLN 133 133 133 GLN GLN A . n 
C 2 134 GLY 134 134 134 GLY GLY A . n 
C 2 135 PHE 135 135 135 PHE PHE A . n 
C 2 136 LEU 136 136 136 LEU LEU A . n 
C 2 137 VAL 137 137 137 VAL VAL A . n 
C 2 138 PHE 138 138 138 PHE PHE A . n 
C 2 139 HIS 139 139 139 HIS HIS A . n 
C 2 140 SER 140 140 140 SER SER A . n 
C 2 141 PHE 141 141 141 PHE PHE A . n 
C 2 142 GLY 142 142 142 GLY GLY A . n 
C 2 143 GLY 143 143 143 GLY GLY A . n 
C 2 144 GLY 144 144 144 GLY GLY A . n 
C 2 145 THR 145 145 145 THR THR A . n 
C 2 146 GLY 146 146 146 GLY GLY A . n 
C 2 147 SER 147 147 147 SER SER A . n 
C 2 148 GLY 148 148 148 GLY GLY A . n 
C 2 149 PHE 149 149 149 PHE PHE A . n 
C 2 150 THR 150 150 150 THR THR A . n 
C 2 151 SER 151 151 151 SER SER A . n 
C 2 152 LEU 152 152 152 LEU LEU A . n 
C 2 153 LEU 153 153 153 LEU LEU A . n 
C 2 154 MET 154 154 154 MET MET A . n 
C 2 155 GLU 155 155 155 GLU GLU A . n 
C 2 156 ARG 156 156 156 ARG ARG A . n 
C 2 157 LEU 157 157 157 LEU LEU A . n 
C 2 158 SER 158 158 158 SER SER A . n 
C 2 159 VAL 159 159 159 VAL VAL A . n 
C 2 160 ASP 160 160 160 ASP ASP A . n 
C 2 161 TYR 161 161 161 TYR TYR A . n 
C 2 162 GLY 162 162 162 GLY GLY A . n 
C 2 163 LYS 163 163 163 LYS LYS A . n 
C 2 164 LYS 164 164 164 LYS LYS A . n 
C 2 165 SER 165 165 165 SER SER A . n 
C 2 166 LYS 166 166 166 LYS LYS A . n 
C 2 167 LEU 167 167 167 LEU LEU A . n 
C 2 168 GLU 168 168 168 GLU GLU A . n 
C 2 169 PHE 169 169 169 PHE PHE A . n 
C 2 170 SER 170 170 170 SER SER A . n 
C 2 171 ILE 171 171 171 ILE ILE A . n 
C 2 172 TYR 172 172 172 TYR TYR A . n 
C 2 173 PRO 173 173 173 PRO PRO A . n 
C 2 174 ALA 174 174 174 ALA ALA A . n 
C 2 175 PRO 175 175 175 PRO PRO A . n 
C 2 176 GLN 176 176 176 GLN GLN A . n 
C 2 177 VAL 177 177 177 VAL VAL A . n 
C 2 178 SER 178 178 178 SER SER A . n 
C 2 179 THR 179 179 179 THR THR A . n 
C 2 180 ALA 180 180 180 ALA ALA A . n 
C 2 181 VAL 181 181 181 VAL VAL A . n 
C 2 182 VAL 182 182 182 VAL VAL A . n 
C 2 183 GLU 183 183 183 GLU GLU A . n 
C 2 184 PRO 184 184 184 PRO PRO A . n 
C 2 185 TYR 185 185 185 TYR TYR A . n 
C 2 186 ASN 186 186 186 ASN ASN A . n 
C 2 187 SER 187 187 187 SER SER A . n 
C 2 188 ILE 188 188 188 ILE ILE A . n 
C 2 189 LEU 189 189 189 LEU LEU A . n 
C 2 190 THR 190 190 190 THR THR A . n 
C 2 191 THR 191 191 191 THR THR A . n 
C 2 192 HIS 192 192 192 HIS HIS A . n 
C 2 193 THR 193 193 193 THR THR A . n 
C 2 194 THR 194 194 194 THR THR A . n 
C 2 195 LEU 195 195 195 LEU LEU A . n 
C 2 196 GLU 196 196 196 GLU GLU A . n 
C 2 197 HIS 197 197 197 HIS HIS A . n 
C 2 198 SER 198 198 198 SER SER A . n 
C 2 199 ASP 199 199 199 ASP ASP A . n 
C 2 200 CYS 200 200 200 CYS CYS A . n 
C 2 201 ALA 201 201 201 ALA ALA A . n 
C 2 202 PHE 202 202 202 PHE PHE A . n 
C 2 203 MET 203 203 203 MET MET A . n 
C 2 204 VAL 204 204 204 VAL VAL A . n 
C 2 205 ASP 205 205 205 ASP ASP A . n 
C 2 206 ASN 206 206 206 ASN ASN A . n 
C 2 207 GLU 207 207 207 GLU GLU A . n 
C 2 208 ALA 208 208 208 ALA ALA A . n 
C 2 209 ILE 209 209 209 ILE ILE A . n 
C 2 210 TYR 210 210 210 TYR TYR A . n 
C 2 211 ASP 211 211 211 ASP ASP A . n 
C 2 212 ILE 212 212 212 ILE ILE A . n 
C 2 213 CYS 213 213 213 CYS CYS A . n 
C 2 214 ARG 214 214 214 ARG ARG A . n 
C 2 215 ARG 215 215 215 ARG ARG A . n 
C 2 216 ASN 216 216 216 ASN ASN A . n 
C 2 217 LEU 217 217 217 LEU LEU A . n 
C 2 218 ASP 218 218 218 ASP ASP A . n 
C 2 219 ILE 219 219 219 ILE ILE A . n 
C 2 220 GLU 220 220 220 GLU GLU A . n 
C 2 221 ARG 221 221 221 ARG ARG A . n 
C 2 222 PRO 222 222 222 PRO PRO A . n 
C 2 223 THR 223 223 223 THR THR A . n 
C 2 224 TYR 224 224 224 TYR TYR A . n 
C 2 225 THR 225 225 225 THR THR A . n 
C 2 226 ASN 226 226 226 ASN ASN A . n 
C 2 227 LEU 227 227 227 LEU LEU A . n 
C 2 228 ASN 228 228 228 ASN ASN A . n 
C 2 229 ARG 229 229 229 ARG ARG A . n 
C 2 230 LEU 230 230 230 LEU LEU A . n 
C 2 231 ILE 231 231 231 ILE ILE A . n 
C 2 232 SER 232 232 232 SER SER A . n 
C 2 233 GLN 233 233 233 GLN GLN A . n 
C 2 234 ILE 234 234 234 ILE ILE A . n 
C 2 235 VAL 235 235 235 VAL VAL A . n 
C 2 236 SER 236 236 236 SER SER A . n 
C 2 237 SER 237 237 237 SER SER A . n 
C 2 238 ILE 238 238 238 ILE ILE A . n 
C 2 239 THR 239 239 239 THR THR A . n 
C 2 240 ALA 240 240 240 ALA ALA A . n 
C 2 241 SER 241 241 241 SER SER A . n 
C 2 242 LEU 242 242 242 LEU LEU A . n 
C 2 243 ARG 243 243 243 ARG ARG A . n 
C 2 244 PHE 244 244 244 PHE PHE A . n 
C 2 245 ASP 245 245 245 ASP ASP A . n 
C 2 246 GLY 246 246 246 GLY GLY A . n 
C 2 247 ALA 247 247 247 ALA ALA A . n 
C 2 248 LEU 248 248 248 LEU LEU A . n 
C 2 249 ASN 249 249 249 ASN ASN A . n 
C 2 250 VAL 250 250 250 VAL VAL A . n 
C 2 251 ASP 251 251 251 ASP ASP A . n 
C 2 252 LEU 252 252 252 LEU LEU A . n 
C 2 253 THR 253 253 253 THR THR A . n 
C 2 254 GLU 254 254 254 GLU GLU A . n 
C 2 255 PHE 255 255 255 PHE PHE A . n 
C 2 256 GLN 256 256 256 GLN GLN A . n 
C 2 257 THR 257 257 257 THR THR A . n 
C 2 258 ASN 258 258 258 ASN ASN A . n 
C 2 259 LEU 259 259 259 LEU LEU A . n 
C 2 260 VAL 260 260 260 VAL VAL A . n 
C 2 261 PRO 261 261 261 PRO PRO A . n 
C 2 262 TYR 262 262 262 TYR TYR A . n 
C 2 263 PRO 263 263 263 PRO PRO A . n 
C 2 264 ARG 264 264 264 ARG ARG A . n 
C 2 265 ILE 265 265 265 ILE ILE A . n 
C 2 266 HIS 266 266 266 HIS HIS A . n 
C 2 267 PHE 267 267 267 PHE PHE A . n 
C 2 268 PRO 268 268 268 PRO PRO A . n 
C 2 269 LEU 269 269 269 LEU LEU A . n 
C 2 270 ALA 270 270 270 ALA ALA A . n 
C 2 271 THR 271 271 271 THR THR A . n 
C 2 272 TYR 272 272 272 TYR TYR A . n 
C 2 273 ALA 273 273 273 ALA ALA A . n 
C 2 274 PRO 274 274 274 PRO PRO A . n 
C 2 275 VAL 275 275 275 VAL VAL A . n 
C 2 276 ILE 276 276 276 ILE ILE A . n 
C 2 277 SER 277 277 277 SER SER A . n 
C 2 278 ALA 278 278 278 ALA ALA A . n 
C 2 279 GLU 279 279 279 GLU GLU A . n 
C 2 280 LYS 280 280 280 LYS LYS A . n 
C 2 281 ALA 281 281 281 ALA ALA A . n 
C 2 282 TYR 282 282 282 TYR TYR A . n 
C 2 283 HIS 283 283 283 HIS HIS A . n 
C 2 284 GLU 284 284 284 GLU GLU A . n 
C 2 285 GLN 285 285 285 GLN GLN A . n 
C 2 286 LEU 286 286 286 LEU LEU A . n 
C 2 287 SER 287 287 287 SER SER A . n 
C 2 288 VAL 288 288 288 VAL VAL A . n 
C 2 289 ALA 289 289 289 ALA ALA A . n 
C 2 290 GLU 290 290 290 GLU GLU A . n 
C 2 291 ILE 291 291 291 ILE ILE A . n 
C 2 292 THR 292 292 292 THR THR A . n 
C 2 293 ASN 293 293 293 ASN ASN A . n 
C 2 294 ALA 294 294 294 ALA ALA A . n 
C 2 295 CYS 295 295 295 CYS CYS A . n 
C 2 296 PHE 296 296 296 PHE PHE A . n 
C 2 297 GLU 297 297 297 GLU GLU A . n 
C 2 298 PRO 298 298 298 PRO PRO A . n 
C 2 299 ALA 299 299 299 ALA ALA A . n 
C 2 300 ASN 300 300 300 ASN ASN A . n 
C 2 301 GLN 301 301 301 GLN GLN A . n 
C 2 302 MET 302 302 302 MET MET A . n 
C 2 303 VAL 303 303 303 VAL VAL A . n 
C 2 304 LYS 304 304 304 LYS LYS A . n 
C 2 305 CYS 305 305 305 CYS CYS A . n 
C 2 306 ASP 306 306 306 ASP ASP A . n 
C 2 307 PRO 307 307 307 PRO PRO A . n 
C 2 308 ARG 308 308 308 ARG ARG A . n 
C 2 309 HIS 309 309 309 HIS HIS A . n 
C 2 310 GLY 310 310 310 GLY GLY A . n 
C 2 311 LYS 311 311 311 LYS LYS A . n 
C 2 312 TYR 312 312 312 TYR TYR A . n 
C 2 313 MET 313 313 313 MET MET A . n 
C 2 314 ALA 314 314 314 ALA ALA A . n 
C 2 315 CYS 315 315 315 CYS CYS A . n 
C 2 316 CYS 316 316 316 CYS CYS A . n 
C 2 317 LEU 317 317 317 LEU LEU A . n 
C 2 318 LEU 318 318 318 LEU LEU A . n 
C 2 319 TYR 319 319 319 TYR TYR A . n 
C 2 320 ARG 320 320 320 ARG ARG A . n 
C 2 321 GLY 321 321 321 GLY GLY A . n 
C 2 322 ASP 322 322 322 ASP ASP A . n 
C 2 323 VAL 323 323 323 VAL VAL A . n 
C 2 324 VAL 324 324 324 VAL VAL A . n 
C 2 325 PRO 325 325 325 PRO PRO A . n 
C 2 326 LYS 326 326 326 LYS LYS A . n 
C 2 327 ASP 327 327 327 ASP ASP A . n 
C 2 328 VAL 328 328 328 VAL VAL A . n 
C 2 329 ASN 329 329 329 ASN ASN A . n 
C 2 330 ALA 330 330 330 ALA ALA A . n 
C 2 331 ALA 331 331 331 ALA ALA A . n 
C 2 332 ILE 332 332 332 ILE ILE A . n 
C 2 333 ALA 333 333 333 ALA ALA A . n 
C 2 334 THR 334 334 334 THR THR A . n 
C 2 335 ILE 335 335 335 ILE ILE A . n 
C 2 336 LYS 336 336 336 LYS LYS A . n 
C 2 337 THR 337 337 337 THR THR A . n 
C 2 338 LYS 338 338 338 LYS LYS A . n 
C 2 339 ARG 339 339 339 ARG ARG A . n 
C 2 340 SER 340 340 340 SER SER A . n 
C 2 341 ILE 341 341 341 ILE ILE A . n 
C 2 342 GLN 342 342 342 GLN GLN A . n 
C 2 343 PHE 343 343 343 PHE PHE A . n 
C 2 344 VAL 344 344 344 VAL VAL A . n 
C 2 345 ASP 345 345 345 ASP ASP A . n 
C 2 346 TRP 346 346 346 TRP TRP A . n 
C 2 347 CYS 347 347 347 CYS CYS A . n 
C 2 348 PRO 348 348 348 PRO PRO A . n 
C 2 349 THR 349 349 349 THR THR A . n 
C 2 350 GLY 350 350 350 GLY GLY A . n 
C 2 351 PHE 351 351 351 PHE PHE A . n 
C 2 352 LYS 352 352 352 LYS LYS A . n 
C 2 353 VAL 353 353 353 VAL VAL A . n 
C 2 354 GLY 354 354 354 GLY GLY A . n 
C 2 355 ILE 355 355 355 ILE ILE A . n 
C 2 356 ASN 356 356 356 ASN ASN A . n 
C 2 357 TYR 357 357 357 TYR TYR A . n 
C 2 358 GLN 358 358 358 GLN GLN A . n 
C 2 359 PRO 359 359 359 PRO PRO A . n 
C 2 360 PRO 360 360 360 PRO PRO A . n 
C 2 361 THR 361 361 361 THR THR A . n 
C 2 362 VAL 362 362 362 VAL VAL A . n 
C 2 363 VAL 363 363 363 VAL VAL A . n 
C 2 364 PRO 364 364 364 PRO PRO A . n 
C 2 365 GLY 365 365 365 GLY GLY A . n 
C 2 366 GLY 366 366 366 GLY GLY A . n 
C 2 367 ASP 367 367 367 ASP ASP A . n 
C 2 368 LEU 368 368 368 LEU LEU A . n 
C 2 369 ALA 369 369 369 ALA ALA A . n 
C 2 370 LYS 370 370 370 LYS LYS A . n 
C 2 371 VAL 371 371 371 VAL VAL A . n 
C 2 372 GLN 372 372 372 GLN GLN A . n 
C 2 373 ARG 373 373 373 ARG ARG A . n 
C 2 374 ALA 374 374 374 ALA ALA A . n 
C 2 375 VAL 375 375 375 VAL VAL A . n 
C 2 376 CYS 376 376 376 CYS CYS A . n 
C 2 377 MET 377 377 377 MET MET A . n 
C 2 378 LEU 378 378 378 LEU LEU A . n 
C 2 379 SER 379 379 379 SER SER A . n 
C 2 380 ASN 380 380 380 ASN ASN A . n 
C 2 381 THR 381 381 381 THR THR A . n 
C 2 382 THR 382 382 382 THR THR A . n 
C 2 383 ALA 383 383 383 ALA ALA A . n 
C 2 384 ILE 384 384 384 ILE ILE A . n 
C 2 385 ALA 385 385 385 ALA ALA A . n 
C 2 386 GLU 386 386 386 GLU GLU A . n 
C 2 387 ALA 387 387 387 ALA ALA A . n 
C 2 388 TRP 388 388 388 TRP TRP A . n 
C 2 389 ALA 389 389 389 ALA ALA A . n 
C 2 390 ARG 390 390 390 ARG ARG A . n 
C 2 391 LEU 391 391 391 LEU LEU A . n 
C 2 392 ASP 392 392 392 ASP ASP A . n 
C 2 393 HIS 393 393 393 HIS HIS A . n 
C 2 394 LYS 394 394 394 LYS LYS A . n 
C 2 395 PHE 395 395 395 PHE PHE A . n 
C 2 396 ASP 396 396 396 ASP ASP A . n 
C 2 397 LEU 397 397 397 LEU LEU A . n 
C 2 398 MET 398 398 398 MET MET A . n 
C 2 399 TYR 399 399 399 TYR TYR A . n 
C 2 400 ALA 400 400 400 ALA ALA A . n 
C 2 401 LYS 401 401 401 LYS LYS A . n 
C 2 402 ARG 402 402 402 ARG ARG A . n 
C 2 403 ALA 403 403 403 ALA ALA A . n 
C 2 404 PHE 404 404 404 PHE PHE A . n 
C 2 405 VAL 405 405 405 VAL VAL A . n 
C 2 406 HIS 406 406 406 HIS HIS A . n 
C 2 407 TRP 407 407 407 TRP TRP A . n 
C 2 408 TYR 408 408 408 TYR TYR A . n 
C 2 409 VAL 409 409 409 VAL VAL A . n 
C 2 410 GLY 410 410 410 GLY GLY A . n 
C 2 411 GLU 411 411 411 GLU GLU A . n 
C 2 412 GLY 412 412 412 GLY GLY A . n 
C 2 413 MET 413 413 413 MET MET A . n 
C 2 414 GLU 414 414 414 GLU GLU A . n 
C 2 415 GLU 415 415 415 GLU GLU A . n 
C 2 416 GLY 416 416 416 GLY GLY A . n 
C 2 417 GLU 417 417 417 GLU GLU A . n 
C 2 418 PHE 418 418 418 PHE PHE A . n 
C 2 419 SER 419 419 419 SER SER A . n 
C 2 420 GLU 420 420 420 GLU GLU A . n 
C 2 421 ALA 421 421 421 ALA ALA A . n 
C 2 422 ARG 422 422 422 ARG ARG A . n 
C 2 423 GLU 423 423 423 GLU GLU A . n 
C 2 424 ASP 424 424 424 ASP ASP A . n 
C 2 425 MET 425 425 425 MET MET A . n 
C 2 426 ALA 426 426 426 ALA ALA A . n 
C 2 427 ALA 427 427 427 ALA ALA A . n 
C 2 428 LEU 428 428 428 LEU LEU A . n 
C 2 429 GLU 429 429 429 GLU GLU A . n 
C 2 430 LYS 430 430 430 LYS LYS A . n 
C 2 431 ASP 431 431 431 ASP ASP A . n 
C 2 432 TYR 432 432 432 TYR TYR A . n 
C 2 433 GLU 433 433 433 GLU GLU A . n 
C 2 434 GLU 434 434 434 GLU GLU A . n 
C 2 435 VAL 435 435 435 VAL VAL A . n 
C 2 436 GLY 436 436 436 GLY GLY A . n 
C 2 437 VAL 437 437 437 VAL VAL A . n 
C 2 438 ASP 438 438 438 ASP ASP A . n 
C 2 439 SER 439 439 439 SER SER A . n 
C 2 440 VAL 440 440 440 VAL VAL A . n 
C 2 441 GLU 441 441 441 GLU GLU A . n 
C 2 442 GLY 442 442 ?   ?   ?   A . n 
C 2 443 GLU 443 443 ?   ?   ?   A . n 
C 2 444 GLY 444 444 ?   ?   ?   A . n 
C 2 445 GLU 445 445 ?   ?   ?   A . n 
C 2 446 GLU 446 446 ?   ?   ?   A . n 
C 2 447 GLU 447 447 ?   ?   ?   A . n 
C 2 448 GLY 448 448 ?   ?   ?   A . n 
C 2 449 GLU 449 449 ?   ?   ?   A . n 
C 2 450 GLU 450 450 ?   ?   ?   A . n 
C 2 451 TYR 451 451 ?   ?   ?   A . n 
D 2 1   MET 1   1   1   MET MET D . n 
D 2 2   ARG 2   2   2   ARG ARG D . n 
D 2 3   GLU 3   3   3   GLU GLU D . n 
D 2 4   CYS 4   4   4   CYS CYS D . n 
D 2 5   ILE 5   5   5   ILE ILE D . n 
D 2 6   SER 6   6   6   SER SER D . n 
D 2 7   ILE 7   7   7   ILE ILE D . n 
D 2 8   HIS 8   8   8   HIS HIS D . n 
D 2 9   VAL 9   9   9   VAL VAL D . n 
D 2 10  GLY 10  10  10  GLY GLY D . n 
D 2 11  GLN 11  11  11  GLN GLN D . n 
D 2 12  ALA 12  12  12  ALA ALA D . n 
D 2 13  GLY 13  13  13  GLY GLY D . n 
D 2 14  VAL 14  14  14  VAL VAL D . n 
D 2 15  GLN 15  15  15  GLN GLN D . n 
D 2 16  ILE 16  16  16  ILE ILE D . n 
D 2 17  GLY 17  17  17  GLY GLY D . n 
D 2 18  ASN 18  18  18  ASN ASN D . n 
D 2 19  ALA 19  19  19  ALA ALA D . n 
D 2 20  CYS 20  20  20  CYS CYS D . n 
D 2 21  TRP 21  21  21  TRP TRP D . n 
D 2 22  GLU 22  22  22  GLU GLU D . n 
D 2 23  LEU 23  23  23  LEU LEU D . n 
D 2 24  TYR 24  24  24  TYR TYR D . n 
D 2 25  CYS 25  25  25  CYS CYS D . n 
D 2 26  LEU 26  26  26  LEU LEU D . n 
D 2 27  GLU 27  27  27  GLU GLU D . n 
D 2 28  HIS 28  28  28  HIS HIS D . n 
D 2 29  GLY 29  29  29  GLY GLY D . n 
D 2 30  ILE 30  30  30  ILE ILE D . n 
D 2 31  GLN 31  31  31  GLN GLN D . n 
D 2 32  PRO 32  32  32  PRO PRO D . n 
D 2 33  ASP 33  33  33  ASP ASP D . n 
D 2 34  GLY 34  34  34  GLY GLY D . n 
D 2 35  GLN 35  35  35  GLN GLN D . n 
D 2 36  MET 36  36  36  MET MET D . n 
D 2 37  PRO 37  37  37  PRO PRO D . n 
D 2 38  SER 38  38  38  SER SER D . n 
D 2 39  ASP 39  39  ?   ?   ?   D . n 
D 2 40  LYS 40  40  ?   ?   ?   D . n 
D 2 41  THR 41  41  ?   ?   ?   D . n 
D 2 42  ILE 42  42  ?   ?   ?   D . n 
D 2 43  GLY 43  43  43  GLY GLY D . n 
D 2 44  GLY 44  44  44  GLY GLY D . n 
D 2 45  GLY 45  45  45  GLY GLY D . n 
D 2 46  ASP 46  46  46  ASP ASP D . n 
D 2 47  ASP 47  47  47  ASP ASP D . n 
D 2 48  SER 48  48  48  SER SER D . n 
D 2 49  PHE 49  49  49  PHE PHE D . n 
D 2 50  ASN 50  50  50  ASN ASN D . n 
D 2 51  THR 51  51  51  THR THR D . n 
D 2 52  PHE 52  52  52  PHE PHE D . n 
D 2 53  PHE 53  53  53  PHE PHE D . n 
D 2 54  SER 54  54  54  SER SER D . n 
D 2 55  GLU 55  55  55  GLU GLU D . n 
D 2 56  THR 56  56  56  THR THR D . n 
D 2 57  GLY 57  57  57  GLY GLY D . n 
D 2 58  ALA 58  58  58  ALA ALA D . n 
D 2 59  GLY 59  59  59  GLY GLY D . n 
D 2 60  LYS 60  60  60  LYS LYS D . n 
D 2 61  HIS 61  61  61  HIS HIS D . n 
D 2 62  VAL 62  62  62  VAL VAL D . n 
D 2 63  PRO 63  63  63  PRO PRO D . n 
D 2 64  ARG 64  64  64  ARG ARG D . n 
D 2 65  ALA 65  65  65  ALA ALA D . n 
D 2 66  VAL 66  66  66  VAL VAL D . n 
D 2 67  PHE 67  67  67  PHE PHE D . n 
D 2 68  VAL 68  68  68  VAL VAL D . n 
D 2 69  ASP 69  69  69  ASP ASP D . n 
D 2 70  LEU 70  70  70  LEU LEU D . n 
D 2 71  GLU 71  71  71  GLU GLU D . n 
D 2 72  PRO 72  72  72  PRO PRO D . n 
D 2 73  THR 73  73  73  THR THR D . n 
D 2 74  VAL 74  74  74  VAL VAL D . n 
D 2 75  ILE 75  75  75  ILE ILE D . n 
D 2 76  ASP 76  76  76  ASP ASP D . n 
D 2 77  GLU 77  77  77  GLU GLU D . n 
D 2 78  VAL 78  78  78  VAL VAL D . n 
D 2 79  ARG 79  79  79  ARG ARG D . n 
D 2 80  THR 80  80  80  THR THR D . n 
D 2 81  GLY 81  81  81  GLY GLY D . n 
D 2 82  THR 82  82  82  THR THR D . n 
D 2 83  TYR 83  83  83  TYR TYR D . n 
D 2 84  ARG 84  84  84  ARG ARG D . n 
D 2 85  GLN 85  85  85  GLN GLN D . n 
D 2 86  LEU 86  86  86  LEU LEU D . n 
D 2 87  PHE 87  87  87  PHE PHE D . n 
D 2 88  HIS 88  88  88  HIS HIS D . n 
D 2 89  PRO 89  89  89  PRO PRO D . n 
D 2 90  GLU 90  90  90  GLU GLU D . n 
D 2 91  GLN 91  91  91  GLN GLN D . n 
D 2 92  LEU 92  92  92  LEU LEU D . n 
D 2 93  ILE 93  93  93  ILE ILE D . n 
D 2 94  THR 94  94  94  THR THR D . n 
D 2 95  GLY 95  95  95  GLY GLY D . n 
D 2 96  LYS 96  96  96  LYS LYS D . n 
D 2 97  GLU 97  97  97  GLU GLU D . n 
D 2 98  ASP 98  98  98  ASP ASP D . n 
D 2 99  ALA 99  99  99  ALA ALA D . n 
D 2 100 ALA 100 100 100 ALA ALA D . n 
D 2 101 ASN 101 101 101 ASN ASN D . n 
D 2 102 ASN 102 102 102 ASN ASN D . n 
D 2 103 TYR 103 103 103 TYR TYR D . n 
D 2 104 ALA 104 104 104 ALA ALA D . n 
D 2 105 ARG 105 105 105 ARG ARG D . n 
D 2 106 GLY 106 106 106 GLY GLY D . n 
D 2 107 HIS 107 107 107 HIS HIS D . n 
D 2 108 TYR 108 108 108 TYR TYR D . n 
D 2 109 THR 109 109 109 THR THR D . n 
D 2 110 ILE 110 110 110 ILE ILE D . n 
D 2 111 GLY 111 111 111 GLY GLY D . n 
D 2 112 LYS 112 112 112 LYS LYS D . n 
D 2 113 GLU 113 113 113 GLU GLU D . n 
D 2 114 ILE 114 114 114 ILE ILE D . n 
D 2 115 ILE 115 115 115 ILE ILE D . n 
D 2 116 ASP 116 116 116 ASP ASP D . n 
D 2 117 LEU 117 117 117 LEU LEU D . n 
D 2 118 VAL 118 118 118 VAL VAL D . n 
D 2 119 LEU 119 119 119 LEU LEU D . n 
D 2 120 ASP 120 120 120 ASP ASP D . n 
D 2 121 ARG 121 121 121 ARG ARG D . n 
D 2 122 ILE 122 122 122 ILE ILE D . n 
D 2 123 ARG 123 123 123 ARG ARG D . n 
D 2 124 LYS 124 124 124 LYS LYS D . n 
D 2 125 LEU 125 125 125 LEU LEU D . n 
D 2 126 ALA 126 126 126 ALA ALA D . n 
D 2 127 ASP 127 127 127 ASP ASP D . n 
D 2 128 GLN 128 128 128 GLN GLN D . n 
D 2 129 CYS 129 129 129 CYS CYS D . n 
D 2 130 THR 130 130 130 THR THR D . n 
D 2 131 GLY 131 131 131 GLY GLY D . n 
D 2 132 LEU 132 132 132 LEU LEU D . n 
D 2 133 GLN 133 133 133 GLN GLN D . n 
D 2 134 GLY 134 134 134 GLY GLY D . n 
D 2 135 PHE 135 135 135 PHE PHE D . n 
D 2 136 LEU 136 136 136 LEU LEU D . n 
D 2 137 VAL 137 137 137 VAL VAL D . n 
D 2 138 PHE 138 138 138 PHE PHE D . n 
D 2 139 HIS 139 139 139 HIS HIS D . n 
D 2 140 SER 140 140 140 SER SER D . n 
D 2 141 PHE 141 141 141 PHE PHE D . n 
D 2 142 GLY 142 142 142 GLY GLY D . n 
D 2 143 GLY 143 143 143 GLY GLY D . n 
D 2 144 GLY 144 144 144 GLY GLY D . n 
D 2 145 THR 145 145 145 THR THR D . n 
D 2 146 GLY 146 146 146 GLY GLY D . n 
D 2 147 SER 147 147 147 SER SER D . n 
D 2 148 GLY 148 148 148 GLY GLY D . n 
D 2 149 PHE 149 149 149 PHE PHE D . n 
D 2 150 THR 150 150 150 THR THR D . n 
D 2 151 SER 151 151 151 SER SER D . n 
D 2 152 LEU 152 152 152 LEU LEU D . n 
D 2 153 LEU 153 153 153 LEU LEU D . n 
D 2 154 MET 154 154 154 MET MET D . n 
D 2 155 GLU 155 155 155 GLU GLU D . n 
D 2 156 ARG 156 156 156 ARG ARG D . n 
D 2 157 LEU 157 157 157 LEU LEU D . n 
D 2 158 SER 158 158 158 SER SER D . n 
D 2 159 VAL 159 159 159 VAL VAL D . n 
D 2 160 ASP 160 160 160 ASP ASP D . n 
D 2 161 TYR 161 161 161 TYR TYR D . n 
D 2 162 GLY 162 162 162 GLY GLY D . n 
D 2 163 LYS 163 163 163 LYS LYS D . n 
D 2 164 LYS 164 164 164 LYS LYS D . n 
D 2 165 SER 165 165 165 SER SER D . n 
D 2 166 LYS 166 166 166 LYS LYS D . n 
D 2 167 LEU 167 167 167 LEU LEU D . n 
D 2 168 GLU 168 168 168 GLU GLU D . n 
D 2 169 PHE 169 169 169 PHE PHE D . n 
D 2 170 SER 170 170 170 SER SER D . n 
D 2 171 ILE 171 171 171 ILE ILE D . n 
D 2 172 TYR 172 172 172 TYR TYR D . n 
D 2 173 PRO 173 173 173 PRO PRO D . n 
D 2 174 ALA 174 174 174 ALA ALA D . n 
D 2 175 PRO 175 175 175 PRO PRO D . n 
D 2 176 GLN 176 176 176 GLN GLN D . n 
D 2 177 VAL 177 177 177 VAL VAL D . n 
D 2 178 SER 178 178 178 SER SER D . n 
D 2 179 THR 179 179 179 THR THR D . n 
D 2 180 ALA 180 180 180 ALA ALA D . n 
D 2 181 VAL 181 181 181 VAL VAL D . n 
D 2 182 VAL 182 182 182 VAL VAL D . n 
D 2 183 GLU 183 183 183 GLU GLU D . n 
D 2 184 PRO 184 184 184 PRO PRO D . n 
D 2 185 TYR 185 185 185 TYR TYR D . n 
D 2 186 ASN 186 186 186 ASN ASN D . n 
D 2 187 SER 187 187 187 SER SER D . n 
D 2 188 ILE 188 188 188 ILE ILE D . n 
D 2 189 LEU 189 189 189 LEU LEU D . n 
D 2 190 THR 190 190 190 THR THR D . n 
D 2 191 THR 191 191 191 THR THR D . n 
D 2 192 HIS 192 192 192 HIS HIS D . n 
D 2 193 THR 193 193 193 THR THR D . n 
D 2 194 THR 194 194 194 THR THR D . n 
D 2 195 LEU 195 195 195 LEU LEU D . n 
D 2 196 GLU 196 196 196 GLU GLU D . n 
D 2 197 HIS 197 197 197 HIS HIS D . n 
D 2 198 SER 198 198 198 SER SER D . n 
D 2 199 ASP 199 199 199 ASP ASP D . n 
D 2 200 CYS 200 200 200 CYS CYS D . n 
D 2 201 ALA 201 201 201 ALA ALA D . n 
D 2 202 PHE 202 202 202 PHE PHE D . n 
D 2 203 MET 203 203 203 MET MET D . n 
D 2 204 VAL 204 204 204 VAL VAL D . n 
D 2 205 ASP 205 205 205 ASP ASP D . n 
D 2 206 ASN 206 206 206 ASN ASN D . n 
D 2 207 GLU 207 207 207 GLU GLU D . n 
D 2 208 ALA 208 208 208 ALA ALA D . n 
D 2 209 ILE 209 209 209 ILE ILE D . n 
D 2 210 TYR 210 210 210 TYR TYR D . n 
D 2 211 ASP 211 211 211 ASP ASP D . n 
D 2 212 ILE 212 212 212 ILE ILE D . n 
D 2 213 CYS 213 213 213 CYS CYS D . n 
D 2 214 ARG 214 214 214 ARG ARG D . n 
D 2 215 ARG 215 215 215 ARG ARG D . n 
D 2 216 ASN 216 216 216 ASN ASN D . n 
D 2 217 LEU 217 217 217 LEU LEU D . n 
D 2 218 ASP 218 218 218 ASP ASP D . n 
D 2 219 ILE 219 219 219 ILE ILE D . n 
D 2 220 GLU 220 220 220 GLU GLU D . n 
D 2 221 ARG 221 221 221 ARG ARG D . n 
D 2 222 PRO 222 222 222 PRO PRO D . n 
D 2 223 THR 223 223 223 THR THR D . n 
D 2 224 TYR 224 224 224 TYR TYR D . n 
D 2 225 THR 225 225 225 THR THR D . n 
D 2 226 ASN 226 226 226 ASN ASN D . n 
D 2 227 LEU 227 227 227 LEU LEU D . n 
D 2 228 ASN 228 228 228 ASN ASN D . n 
D 2 229 ARG 229 229 229 ARG ARG D . n 
D 2 230 LEU 230 230 230 LEU LEU D . n 
D 2 231 ILE 231 231 231 ILE ILE D . n 
D 2 232 SER 232 232 232 SER SER D . n 
D 2 233 GLN 233 233 233 GLN GLN D . n 
D 2 234 ILE 234 234 234 ILE ILE D . n 
D 2 235 VAL 235 235 235 VAL VAL D . n 
D 2 236 SER 236 236 236 SER SER D . n 
D 2 237 SER 237 237 237 SER SER D . n 
D 2 238 ILE 238 238 238 ILE ILE D . n 
D 2 239 THR 239 239 239 THR THR D . n 
D 2 240 ALA 240 240 240 ALA ALA D . n 
D 2 241 SER 241 241 241 SER SER D . n 
D 2 242 LEU 242 242 242 LEU LEU D . n 
D 2 243 ARG 243 243 243 ARG ARG D . n 
D 2 244 PHE 244 244 244 PHE PHE D . n 
D 2 245 ASP 245 245 245 ASP ASP D . n 
D 2 246 GLY 246 246 246 GLY GLY D . n 
D 2 247 ALA 247 247 247 ALA ALA D . n 
D 2 248 LEU 248 248 248 LEU LEU D . n 
D 2 249 ASN 249 249 249 ASN ASN D . n 
D 2 250 VAL 250 250 250 VAL VAL D . n 
D 2 251 ASP 251 251 251 ASP ASP D . n 
D 2 252 LEU 252 252 252 LEU LEU D . n 
D 2 253 THR 253 253 253 THR THR D . n 
D 2 254 GLU 254 254 254 GLU GLU D . n 
D 2 255 PHE 255 255 255 PHE PHE D . n 
D 2 256 GLN 256 256 256 GLN GLN D . n 
D 2 257 THR 257 257 257 THR THR D . n 
D 2 258 ASN 258 258 258 ASN ASN D . n 
D 2 259 LEU 259 259 259 LEU LEU D . n 
D 2 260 VAL 260 260 260 VAL VAL D . n 
D 2 261 PRO 261 261 261 PRO PRO D . n 
D 2 262 TYR 262 262 262 TYR TYR D . n 
D 2 263 PRO 263 263 263 PRO PRO D . n 
D 2 264 ARG 264 264 264 ARG ARG D . n 
D 2 265 ILE 265 265 265 ILE ILE D . n 
D 2 266 HIS 266 266 266 HIS HIS D . n 
D 2 267 PHE 267 267 267 PHE PHE D . n 
D 2 268 PRO 268 268 268 PRO PRO D . n 
D 2 269 LEU 269 269 269 LEU LEU D . n 
D 2 270 ALA 270 270 270 ALA ALA D . n 
D 2 271 THR 271 271 271 THR THR D . n 
D 2 272 TYR 272 272 272 TYR TYR D . n 
D 2 273 ALA 273 273 273 ALA ALA D . n 
D 2 274 PRO 274 274 274 PRO PRO D . n 
D 2 275 VAL 275 275 275 VAL VAL D . n 
D 2 276 ILE 276 276 276 ILE ILE D . n 
D 2 277 SER 277 277 277 SER SER D . n 
D 2 278 ALA 278 278 278 ALA ALA D . n 
D 2 279 GLU 279 279 279 GLU GLU D . n 
D 2 280 LYS 280 280 280 LYS LYS D . n 
D 2 281 ALA 281 281 281 ALA ALA D . n 
D 2 282 TYR 282 282 282 TYR TYR D . n 
D 2 283 HIS 283 283 283 HIS HIS D . n 
D 2 284 GLU 284 284 284 GLU GLU D . n 
D 2 285 GLN 285 285 285 GLN GLN D . n 
D 2 286 LEU 286 286 286 LEU LEU D . n 
D 2 287 SER 287 287 287 SER SER D . n 
D 2 288 VAL 288 288 288 VAL VAL D . n 
D 2 289 ALA 289 289 289 ALA ALA D . n 
D 2 290 GLU 290 290 290 GLU GLU D . n 
D 2 291 ILE 291 291 291 ILE ILE D . n 
D 2 292 THR 292 292 292 THR THR D . n 
D 2 293 ASN 293 293 293 ASN ASN D . n 
D 2 294 ALA 294 294 294 ALA ALA D . n 
D 2 295 CYS 295 295 295 CYS CYS D . n 
D 2 296 PHE 296 296 296 PHE PHE D . n 
D 2 297 GLU 297 297 297 GLU GLU D . n 
D 2 298 PRO 298 298 298 PRO PRO D . n 
D 2 299 ALA 299 299 299 ALA ALA D . n 
D 2 300 ASN 300 300 300 ASN ASN D . n 
D 2 301 GLN 301 301 301 GLN GLN D . n 
D 2 302 MET 302 302 302 MET MET D . n 
D 2 303 VAL 303 303 303 VAL VAL D . n 
D 2 304 LYS 304 304 304 LYS LYS D . n 
D 2 305 CYS 305 305 305 CYS CYS D . n 
D 2 306 ASP 306 306 306 ASP ASP D . n 
D 2 307 PRO 307 307 307 PRO PRO D . n 
D 2 308 ARG 308 308 308 ARG ARG D . n 
D 2 309 HIS 309 309 309 HIS HIS D . n 
D 2 310 GLY 310 310 310 GLY GLY D . n 
D 2 311 LYS 311 311 311 LYS LYS D . n 
D 2 312 TYR 312 312 312 TYR TYR D . n 
D 2 313 MET 313 313 313 MET MET D . n 
D 2 314 ALA 314 314 314 ALA ALA D . n 
D 2 315 CYS 315 315 315 CYS CYS D . n 
D 2 316 CYS 316 316 316 CYS CYS D . n 
D 2 317 LEU 317 317 317 LEU LEU D . n 
D 2 318 LEU 318 318 318 LEU LEU D . n 
D 2 319 TYR 319 319 319 TYR TYR D . n 
D 2 320 ARG 320 320 320 ARG ARG D . n 
D 2 321 GLY 321 321 321 GLY GLY D . n 
D 2 322 ASP 322 322 322 ASP ASP D . n 
D 2 323 VAL 323 323 323 VAL VAL D . n 
D 2 324 VAL 324 324 324 VAL VAL D . n 
D 2 325 PRO 325 325 325 PRO PRO D . n 
D 2 326 LYS 326 326 326 LYS LYS D . n 
D 2 327 ASP 327 327 327 ASP ASP D . n 
D 2 328 VAL 328 328 328 VAL VAL D . n 
D 2 329 ASN 329 329 329 ASN ASN D . n 
D 2 330 ALA 330 330 330 ALA ALA D . n 
D 2 331 ALA 331 331 331 ALA ALA D . n 
D 2 332 ILE 332 332 332 ILE ILE D . n 
D 2 333 ALA 333 333 333 ALA ALA D . n 
D 2 334 THR 334 334 334 THR THR D . n 
D 2 335 ILE 335 335 335 ILE ILE D . n 
D 2 336 LYS 336 336 336 LYS LYS D . n 
D 2 337 THR 337 337 337 THR THR D . n 
D 2 338 LYS 338 338 338 LYS LYS D . n 
D 2 339 ARG 339 339 339 ARG ARG D . n 
D 2 340 SER 340 340 340 SER SER D . n 
D 2 341 ILE 341 341 341 ILE ILE D . n 
D 2 342 GLN 342 342 342 GLN GLN D . n 
D 2 343 PHE 343 343 343 PHE PHE D . n 
D 2 344 VAL 344 344 344 VAL VAL D . n 
D 2 345 ASP 345 345 345 ASP ASP D . n 
D 2 346 TRP 346 346 346 TRP TRP D . n 
D 2 347 CYS 347 347 347 CYS CYS D . n 
D 2 348 PRO 348 348 348 PRO PRO D . n 
D 2 349 THR 349 349 349 THR THR D . n 
D 2 350 GLY 350 350 350 GLY GLY D . n 
D 2 351 PHE 351 351 351 PHE PHE D . n 
D 2 352 LYS 352 352 352 LYS LYS D . n 
D 2 353 VAL 353 353 353 VAL VAL D . n 
D 2 354 GLY 354 354 354 GLY GLY D . n 
D 2 355 ILE 355 355 355 ILE ILE D . n 
D 2 356 ASN 356 356 356 ASN ASN D . n 
D 2 357 TYR 357 357 357 TYR TYR D . n 
D 2 358 GLN 358 358 358 GLN GLN D . n 
D 2 359 PRO 359 359 359 PRO PRO D . n 
D 2 360 PRO 360 360 360 PRO PRO D . n 
D 2 361 THR 361 361 361 THR THR D . n 
D 2 362 VAL 362 362 362 VAL VAL D . n 
D 2 363 VAL 363 363 363 VAL VAL D . n 
D 2 364 PRO 364 364 364 PRO PRO D . n 
D 2 365 GLY 365 365 365 GLY GLY D . n 
D 2 366 GLY 366 366 366 GLY GLY D . n 
D 2 367 ASP 367 367 367 ASP ASP D . n 
D 2 368 LEU 368 368 368 LEU LEU D . n 
D 2 369 ALA 369 369 369 ALA ALA D . n 
D 2 370 LYS 370 370 370 LYS LYS D . n 
D 2 371 VAL 371 371 371 VAL VAL D . n 
D 2 372 GLN 372 372 372 GLN GLN D . n 
D 2 373 ARG 373 373 373 ARG ARG D . n 
D 2 374 ALA 374 374 374 ALA ALA D . n 
D 2 375 VAL 375 375 375 VAL VAL D . n 
D 2 376 CYS 376 376 376 CYS CYS D . n 
D 2 377 MET 377 377 377 MET MET D . n 
D 2 378 LEU 378 378 378 LEU LEU D . n 
D 2 379 SER 379 379 379 SER SER D . n 
D 2 380 ASN 380 380 380 ASN ASN D . n 
D 2 381 THR 381 381 381 THR THR D . n 
D 2 382 THR 382 382 382 THR THR D . n 
D 2 383 ALA 383 383 383 ALA ALA D . n 
D 2 384 ILE 384 384 384 ILE ILE D . n 
D 2 385 ALA 385 385 385 ALA ALA D . n 
D 2 386 GLU 386 386 386 GLU GLU D . n 
D 2 387 ALA 387 387 387 ALA ALA D . n 
D 2 388 TRP 388 388 388 TRP TRP D . n 
D 2 389 ALA 389 389 389 ALA ALA D . n 
D 2 390 ARG 390 390 390 ARG ARG D . n 
D 2 391 LEU 391 391 391 LEU LEU D . n 
D 2 392 ASP 392 392 392 ASP ASP D . n 
D 2 393 HIS 393 393 393 HIS HIS D . n 
D 2 394 LYS 394 394 394 LYS LYS D . n 
D 2 395 PHE 395 395 395 PHE PHE D . n 
D 2 396 ASP 396 396 396 ASP ASP D . n 
D 2 397 LEU 397 397 397 LEU LEU D . n 
D 2 398 MET 398 398 398 MET MET D . n 
D 2 399 TYR 399 399 399 TYR TYR D . n 
D 2 400 ALA 400 400 400 ALA ALA D . n 
D 2 401 LYS 401 401 401 LYS LYS D . n 
D 2 402 ARG 402 402 402 ARG ARG D . n 
D 2 403 ALA 403 403 403 ALA ALA D . n 
D 2 404 PHE 404 404 404 PHE PHE D . n 
D 2 405 VAL 405 405 405 VAL VAL D . n 
D 2 406 HIS 406 406 406 HIS HIS D . n 
D 2 407 TRP 407 407 407 TRP TRP D . n 
D 2 408 TYR 408 408 408 TYR TYR D . n 
D 2 409 VAL 409 409 409 VAL VAL D . n 
D 2 410 GLY 410 410 410 GLY GLY D . n 
D 2 411 GLU 411 411 411 GLU GLU D . n 
D 2 412 GLY 412 412 412 GLY GLY D . n 
D 2 413 MET 413 413 413 MET MET D . n 
D 2 414 GLU 414 414 414 GLU GLU D . n 
D 2 415 GLU 415 415 415 GLU GLU D . n 
D 2 416 GLY 416 416 416 GLY GLY D . n 
D 2 417 GLU 417 417 417 GLU GLU D . n 
D 2 418 PHE 418 418 418 PHE PHE D . n 
D 2 419 SER 419 419 419 SER SER D . n 
D 2 420 GLU 420 420 420 GLU GLU D . n 
D 2 421 ALA 421 421 421 ALA ALA D . n 
D 2 422 ARG 422 422 422 ARG ARG D . n 
D 2 423 GLU 423 423 423 GLU GLU D . n 
D 2 424 ASP 424 424 424 ASP ASP D . n 
D 2 425 MET 425 425 425 MET MET D . n 
D 2 426 ALA 426 426 426 ALA ALA D . n 
D 2 427 ALA 427 427 427 ALA ALA D . n 
D 2 428 LEU 428 428 428 LEU LEU D . n 
D 2 429 GLU 429 429 429 GLU GLU D . n 
D 2 430 LYS 430 430 430 LYS LYS D . n 
D 2 431 ASP 431 431 431 ASP ASP D . n 
D 2 432 TYR 432 432 432 TYR TYR D . n 
D 2 433 GLU 433 433 433 GLU GLU D . n 
D 2 434 GLU 434 434 434 GLU GLU D . n 
D 2 435 VAL 435 435 435 VAL VAL D . n 
D 2 436 GLY 436 436 436 GLY GLY D . n 
D 2 437 VAL 437 437 437 VAL VAL D . n 
D 2 438 ASP 438 438 438 ASP ASP D . n 
D 2 439 SER 439 439 439 SER SER D . n 
D 2 440 VAL 440 440 440 VAL VAL D . n 
D 2 441 GLU 441 441 441 GLU GLU D . n 
D 2 442 GLY 442 442 ?   ?   ?   D . n 
D 2 443 GLU 443 443 ?   ?   ?   D . n 
D 2 444 GLY 444 444 ?   ?   ?   D . n 
D 2 445 GLU 445 445 ?   ?   ?   D . n 
D 2 446 GLU 446 446 ?   ?   ?   D . n 
D 2 447 GLU 447 447 ?   ?   ?   D . n 
D 2 448 GLY 448 448 ?   ?   ?   D . n 
D 2 449 GLU 449 449 ?   ?   ?   D . n 
D 2 450 GLU 450 450 ?   ?   ?   D . n 
D 2 451 TYR 451 451 ?   ?   ?   D . n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
E 3 GDP 1 501 501 GDP GDP B . 
F 3 GDP 1 501 501 GDP GDP E . 
G 4 GTP 1 501 501 GTP GTP A . 
H 5 MG  1 502 502 MG  MG  A . 
I 4 GTP 1 501 501 GTP GTP D . 
J 5 MG  1 502 502 MG  MG  D . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1   1 Y 1 B MET 1   ? CG  ? A MET 1   CG  
2   1 Y 1 B MET 1   ? SD  ? A MET 1   SD  
3   1 Y 1 B MET 1   ? CE  ? A MET 1   CE  
4   1 Y 1 B LYS 174 ? CG  ? A LYS 174 CG  
5   1 Y 1 B LYS 174 ? CD  ? A LYS 174 CD  
6   1 Y 1 B LYS 174 ? CE  ? A LYS 174 CE  
7   1 Y 1 B LYS 174 ? NZ  ? A LYS 174 NZ  
8   1 Y 1 B ARG 276 ? CG  ? A ARG 276 CG  
9   1 Y 1 B ARG 276 ? CD  ? A ARG 276 CD  
10  1 Y 1 B ARG 276 ? NE  ? A ARG 276 NE  
11  1 Y 1 B ARG 276 ? CZ  ? A ARG 276 CZ  
12  1 Y 1 B ARG 276 ? NH1 ? A ARG 276 NH1 
13  1 Y 1 B ARG 276 ? NH2 ? A ARG 276 NH2 
14  1 Y 1 B ARG 282 ? CG  ? A ARG 282 CG  
15  1 Y 1 B ARG 282 ? CD  ? A ARG 282 CD  
16  1 Y 1 B ARG 282 ? NE  ? A ARG 282 NE  
17  1 Y 1 B ARG 282 ? CZ  ? A ARG 282 CZ  
18  1 Y 1 B ARG 282 ? NH1 ? A ARG 282 NH1 
19  1 Y 1 B ARG 282 ? NH2 ? A ARG 282 NH2 
20  1 Y 1 B LYS 297 ? CG  ? A LYS 297 CG  
21  1 Y 1 B LYS 297 ? CD  ? A LYS 297 CD  
22  1 Y 1 B LYS 297 ? CE  ? A LYS 297 CE  
23  1 Y 1 B LYS 297 ? NZ  ? A LYS 297 NZ  
24  1 Y 1 B ARG 320 ? CG  ? A ARG 320 CG  
25  1 Y 1 B ARG 320 ? CD  ? A ARG 320 CD  
26  1 Y 1 B ARG 320 ? NE  ? A ARG 320 NE  
27  1 Y 1 B ARG 320 ? CZ  ? A ARG 320 CZ  
28  1 Y 1 B ARG 320 ? NH1 ? A ARG 320 NH1 
29  1 Y 1 B ARG 320 ? NH2 ? A ARG 320 NH2 
30  1 Y 1 B ASP 427 ? CG  ? A ASP 427 CG  
31  1 Y 1 B ASP 427 ? OD1 ? A ASP 427 OD1 
32  1 Y 1 B ASP 427 ? OD2 ? A ASP 427 OD2 
33  1 Y 1 B THR 429 ? OG1 ? A THR 429 OG1 
34  1 Y 1 B THR 429 ? CG2 ? A THR 429 CG2 
35  1 Y 1 E MET 1   ? CG  ? B MET 1   CG  
36  1 Y 1 E MET 1   ? SD  ? B MET 1   SD  
37  1 Y 1 E MET 1   ? CE  ? B MET 1   CE  
38  1 Y 1 E LYS 174 ? CG  ? B LYS 174 CG  
39  1 Y 1 E LYS 174 ? CD  ? B LYS 174 CD  
40  1 Y 1 E LYS 174 ? CE  ? B LYS 174 CE  
41  1 Y 1 E LYS 174 ? NZ  ? B LYS 174 NZ  
42  1 Y 1 E ARG 276 ? CG  ? B ARG 276 CG  
43  1 Y 1 E ARG 276 ? CD  ? B ARG 276 CD  
44  1 Y 1 E ARG 276 ? NE  ? B ARG 276 NE  
45  1 Y 1 E ARG 276 ? CZ  ? B ARG 276 CZ  
46  1 Y 1 E ARG 276 ? NH1 ? B ARG 276 NH1 
47  1 Y 1 E ARG 276 ? NH2 ? B ARG 276 NH2 
48  1 Y 1 E LYS 297 ? CG  ? B LYS 297 CG  
49  1 Y 1 E LYS 297 ? CD  ? B LYS 297 CD  
50  1 Y 1 E LYS 297 ? CE  ? B LYS 297 CE  
51  1 Y 1 E LYS 297 ? NZ  ? B LYS 297 NZ  
52  1 Y 1 E ARG 320 ? CG  ? B ARG 320 CG  
53  1 Y 1 E ARG 320 ? CD  ? B ARG 320 CD  
54  1 Y 1 E ARG 320 ? NE  ? B ARG 320 NE  
55  1 Y 1 E ARG 320 ? CZ  ? B ARG 320 CZ  
56  1 Y 1 E ARG 320 ? NH1 ? B ARG 320 NH1 
57  1 Y 1 E ARG 320 ? NH2 ? B ARG 320 NH2 
58  1 Y 1 E LYS 336 ? CG  ? B LYS 336 CG  
59  1 Y 1 E LYS 336 ? CD  ? B LYS 336 CD  
60  1 Y 1 E LYS 336 ? CE  ? B LYS 336 CE  
61  1 Y 1 E LYS 336 ? NZ  ? B LYS 336 NZ  
62  1 Y 1 E ASP 427 ? CG  ? B ASP 427 CG  
63  1 Y 1 E ASP 427 ? OD1 ? B ASP 427 OD1 
64  1 Y 1 E ASP 427 ? OD2 ? B ASP 427 OD2 
65  1 Y 1 E THR 429 ? OG1 ? B THR 429 OG1 
66  1 Y 1 E THR 429 ? CG2 ? B THR 429 CG2 
67  1 Y 1 A ARG 221 ? CG  ? C ARG 221 CG  
68  1 Y 1 A ARG 221 ? CD  ? C ARG 221 CD  
69  1 Y 1 A ARG 221 ? NE  ? C ARG 221 NE  
70  1 Y 1 A ARG 221 ? CZ  ? C ARG 221 CZ  
71  1 Y 1 A ARG 221 ? NH1 ? C ARG 221 NH1 
72  1 Y 1 A ARG 221 ? NH2 ? C ARG 221 NH2 
73  1 Y 1 A ASP 438 ? CG  ? C ASP 438 CG  
74  1 Y 1 A ASP 438 ? OD1 ? C ASP 438 OD1 
75  1 Y 1 A ASP 438 ? OD2 ? C ASP 438 OD2 
76  1 Y 1 A SER 439 ? OG  ? C SER 439 OG  
77  1 Y 1 A VAL 440 ? CG1 ? C VAL 440 CG1 
78  1 Y 1 A VAL 440 ? CG2 ? C VAL 440 CG2 
79  1 Y 1 A GLU 441 ? CG  ? C GLU 441 CG  
80  1 Y 1 A GLU 441 ? CD  ? C GLU 441 CD  
81  1 Y 1 A GLU 441 ? OE1 ? C GLU 441 OE1 
82  1 Y 1 A GLU 441 ? OE2 ? C GLU 441 OE2 
83  1 Y 1 D LYS 163 ? CG  ? D LYS 163 CG  
84  1 Y 1 D LYS 163 ? CD  ? D LYS 163 CD  
85  1 Y 1 D LYS 163 ? CE  ? D LYS 163 CE  
86  1 Y 1 D LYS 163 ? NZ  ? D LYS 163 NZ  
87  1 Y 1 D ARG 221 ? CG  ? D ARG 221 CG  
88  1 Y 1 D ARG 221 ? CD  ? D ARG 221 CD  
89  1 Y 1 D ARG 221 ? NE  ? D ARG 221 NE  
90  1 Y 1 D ARG 221 ? CZ  ? D ARG 221 CZ  
91  1 Y 1 D ARG 221 ? NH1 ? D ARG 221 NH1 
92  1 Y 1 D ARG 221 ? NH2 ? D ARG 221 NH2 
93  1 Y 1 D ASP 438 ? CG  ? D ASP 438 CG  
94  1 Y 1 D ASP 438 ? OD1 ? D ASP 438 OD1 
95  1 Y 1 D ASP 438 ? OD2 ? D ASP 438 OD2 
96  1 Y 1 D SER 439 ? OG  ? D SER 439 OG  
97  1 Y 1 D VAL 440 ? CG1 ? D VAL 440 CG1 
98  1 Y 1 D VAL 440 ? CG2 ? D VAL 440 CG2 
99  1 Y 1 D GLU 441 ? CG  ? D GLU 441 CG  
100 1 Y 1 D GLU 441 ? CD  ? D GLU 441 CD  
101 1 Y 1 D GLU 441 ? OE1 ? D GLU 441 OE1 
102 1 Y 1 D GLU 441 ? OE2 ? D GLU 441 OE2 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8V2J 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8V2J 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8V2J 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.entry_id                                 8V2J 
_refine.pdbx_diffrn_id                           ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             ? 
_refine.ls_d_res_high                            . 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.B_iso_mean                               ? 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_ksol                 ? 
_refine.solvent_model_param_bsol                 ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.details                                  ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.006  ? 13890 ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.963  ? 18889 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 10.954 ? 1923  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.049  ? 2078  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.006  ? 2463  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     8V2J 
_struct.title                        'Structure of alpha1B and betaI/IVb microtubule bound to GDP' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8V2J 
_struct_keywords.text            'human microtubule, cytoskeleton, tubulin isoforms, STRUCTURAL PROTEIN' 
_struct_keywords.pdbx_keywords   'STRUCTURAL PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 2 ? 
D N N 2 ? 
E N N 3 ? 
F N N 3 ? 
G N N 4 ? 
H N N 5 ? 
I N N 4 ? 
J N N 5 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP TBB5_HUMAN  P07437 ? 1 
;MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLDRISVYYNEATGGKYVPRAILVDLEPGTMDSVRSGP
FGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYP
DRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL
RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQVFDAKNMMAACDPRHGRYLTVAAVFRGR
MSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMAVTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTG
EGMDEMEFTEAESNMNDLVSEYQQYQDATAEEEEDFGEEAEEEA
;
1 
2 UNP TBA1B_HUMAN P68363 ? 2 
;MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRT
GTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVD
YGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITA
SLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYR
GDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYA
KRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSVEGEGEEEGEEY
;
1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8V2J B 1 ? 444 ? P07437 1 ? 444 ? 1 444 
2 1 8V2J E 1 ? 444 ? P07437 1 ? 444 ? 1 444 
3 2 8V2J A 1 ? 451 ? P68363 1 ? 451 ? 1 451 
4 2 8V2J D 1 ? 451 ? P68363 1 ? 451 ? 1 451 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   tetrameric 
_pdbx_struct_assembly.oligomeric_count     4 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I,J 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 GLY A 10  ? GLY A 29  ? GLY B 10  GLY B 29  1 ? 20 
HELX_P HELX_P2  AA2 SER A 40  ? ARG A 46  ? SER B 40  ARG B 46  1 ? 7  
HELX_P HELX_P3  AA3 ILE A 47  ? VAL A 49  ? ILE B 47  VAL B 49  5 ? 3  
HELX_P HELX_P4  AA4 THR A 55  ? GLY A 57  ? THR B 55  GLY B 57  5 ? 3  
HELX_P HELX_P5  AA5 PRO A 70  ? GLY A 79  ? PRO B 70  GLY B 79  1 ? 10 
HELX_P HELX_P6  AA6 ASN A 100 ? TYR A 106 ? ASN B 100 TYR B 106 1 ? 7  
HELX_P HELX_P7  AA7 TYR A 106 ? CYS A 127 ? TYR B 106 CYS B 127 1 ? 22 
HELX_P HELX_P8  AA8 GLY A 141 ? TYR A 159 ? GLY B 141 TYR B 159 1 ? 19 
HELX_P HELX_P9  AA9 VAL A 180 ? THR A 196 ? VAL B 180 THR B 196 1 ? 17 
HELX_P HELX_P10 AB1 ASP A 203 ? THR A 214 ? ASP B 203 THR B 214 1 ? 12 
HELX_P HELX_P11 AB2 THR A 221 ? THR A 237 ? THR B 221 THR B 237 1 ? 17 
HELX_P HELX_P12 AB3 THR A 237 ? PHE A 242 ? THR B 237 PHE B 242 1 ? 6  
HELX_P HELX_P13 AB4 ASP A 249 ? VAL A 258 ? ASP B 249 VAL B 258 1 ? 10 
HELX_P HELX_P14 AB5 GLY A 277 ? ARG A 282 ? GLY B 277 ARG B 282 1 ? 6  
HELX_P HELX_P15 AB6 THR A 285 ? ASP A 295 ? THR B 285 ASP B 295 1 ? 11 
HELX_P HELX_P16 AB7 ALA A 296 ? MET A 299 ? ALA B 296 MET B 299 5 ? 4  
HELX_P HELX_P17 AB8 ASP A 304 ? GLY A 308 ? ASP B 304 GLY B 308 5 ? 5  
HELX_P HELX_P18 AB9 SER A 322 ? ASN A 337 ? SER B 322 ASN B 337 1 ? 16 
HELX_P HELX_P19 AC1 SER A 338 ? PHE A 341 ? SER B 338 PHE B 341 5 ? 4  
HELX_P HELX_P20 AC2 ALA A 373 ? LYS A 392 ? ALA B 373 LYS B 392 1 ? 20 
HELX_P HELX_P21 AC3 PHE A 394 ? GLU A 401 ? PHE B 394 GLU B 401 1 ? 8  
HELX_P HELX_P22 AC4 ASP A 404 ? ALA A 428 ? ASP B 404 ALA B 428 1 ? 25 
HELX_P HELX_P23 AC5 GLY B 10  ? HIS B 28  ? GLY E 10  HIS E 28  1 ? 19 
HELX_P HELX_P24 AC6 SER B 40  ? ARG B 46  ? SER E 40  ARG E 46  1 ? 7  
HELX_P HELX_P25 AC7 ILE B 47  ? VAL B 49  ? ILE E 47  VAL E 49  5 ? 3  
HELX_P HELX_P26 AC8 PRO B 70  ? GLY B 79  ? PRO E 70  GLY E 79  1 ? 10 
HELX_P HELX_P27 AC9 ARG B 86  ? ASP B 88  ? ARG E 86  ASP E 88  5 ? 3  
HELX_P HELX_P28 AD1 ASN B 100 ? TYR B 106 ? ASN E 100 TYR E 106 1 ? 7  
HELX_P HELX_P29 AD2 GLU B 108 ? CYS B 127 ? GLU E 108 CYS E 127 1 ? 20 
HELX_P HELX_P30 AD3 GLY B 141 ? TYR B 159 ? GLY E 141 TYR E 159 1 ? 19 
HELX_P HELX_P31 AD4 VAL B 180 ? THR B 196 ? VAL E 180 THR E 196 1 ? 17 
HELX_P HELX_P32 AD5 ASN B 204 ? THR B 214 ? ASN E 204 THR E 214 1 ? 11 
HELX_P HELX_P33 AD6 THR B 221 ? THR B 237 ? THR E 221 THR E 237 1 ? 17 
HELX_P HELX_P34 AD7 THR B 237 ? PHE B 242 ? THR E 237 PHE E 242 1 ? 6  
HELX_P HELX_P35 AD8 ASP B 249 ? VAL B 258 ? ASP E 249 VAL E 258 1 ? 10 
HELX_P HELX_P36 AD9 GLY B 277 ? ARG B 282 ? GLY E 277 ARG E 282 1 ? 6  
HELX_P HELX_P37 AE1 THR B 285 ? ASP B 295 ? THR E 285 ASP E 295 1 ? 11 
HELX_P HELX_P38 AE2 LYS B 324 ? ASN B 337 ? LYS E 324 ASN E 337 1 ? 14 
HELX_P HELX_P39 AE3 SER B 338 ? PHE B 341 ? SER E 338 PHE E 341 5 ? 4  
HELX_P HELX_P40 AE4 ALA B 373 ? ARG B 391 ? ALA E 373 ARG E 391 1 ? 19 
HELX_P HELX_P41 AE5 PHE B 394 ? GLU B 401 ? PHE E 394 GLU E 401 1 ? 8  
HELX_P HELX_P42 AE6 ASP B 404 ? ALA B 428 ? ASP E 404 ALA E 428 1 ? 25 
HELX_P HELX_P43 AE7 GLY C 10  ? GLY C 29  ? GLY A 10  GLY A 29  1 ? 20 
HELX_P HELX_P44 AE8 GLY C 44  ? THR C 51  ? GLY A 44  THR A 51  1 ? 8  
HELX_P HELX_P45 AE9 PRO C 72  ? GLY C 81  ? PRO A 72  GLY A 81  1 ? 10 
HELX_P HELX_P46 AF1 ASN C 102 ? TYR C 108 ? ASN A 102 TYR A 108 1 ? 7  
HELX_P HELX_P47 AF2 TYR C 108 ? CYS C 129 ? TYR A 108 CYS A 129 1 ? 22 
HELX_P HELX_P48 AF3 GLY C 143 ? GLY C 162 ? GLY A 143 GLY A 162 1 ? 20 
HELX_P HELX_P49 AF4 VAL C 182 ? SER C 198 ? VAL A 182 SER A 198 1 ? 17 
HELX_P HELX_P50 AF5 ASP C 205 ? ASN C 216 ? ASP A 205 ASN A 216 1 ? 12 
HELX_P HELX_P51 AF6 THR C 223 ? PHE C 244 ? THR A 223 PHE A 244 1 ? 22 
HELX_P HELX_P52 AF7 ASP C 251 ? VAL C 260 ? ASP A 251 VAL A 260 1 ? 10 
HELX_P HELX_P53 AF8 SER C 277 ? TYR C 282 ? SER A 277 TYR A 282 1 ? 6  
HELX_P HELX_P54 AF9 SER C 287 ? PHE C 296 ? SER A 287 PHE A 296 1 ? 10 
HELX_P HELX_P55 AG1 ASP C 306 ? GLY C 310 ? ASP A 306 GLY A 310 5 ? 5  
HELX_P HELX_P56 AG2 VAL C 324 ? LYS C 338 ? VAL A 324 LYS A 338 1 ? 15 
HELX_P HELX_P57 AG3 ALA C 383 ? ALA C 400 ? ALA A 383 ALA A 400 1 ? 18 
HELX_P HELX_P58 AG4 PHE C 404 ? GLU C 411 ? PHE A 404 GLU A 411 1 ? 8  
HELX_P HELX_P59 AG5 GLU C 414 ? GLY C 436 ? GLU A 414 GLY A 436 1 ? 23 
HELX_P HELX_P60 AG6 GLY D 10  ? GLY D 29  ? GLY D 10  GLY D 29  1 ? 20 
HELX_P HELX_P61 AG7 GLY D 44  ? THR D 51  ? GLY D 44  THR D 51  1 ? 8  
HELX_P HELX_P62 AG8 PRO D 72  ? GLY D 81  ? PRO D 72  GLY D 81  1 ? 10 
HELX_P HELX_P63 AG9 THR D 82  ? GLN D 85  ? THR D 82  GLN D 85  5 ? 4  
HELX_P HELX_P64 AH1 ASN D 102 ? TYR D 108 ? ASN D 102 TYR D 108 1 ? 7  
HELX_P HELX_P65 AH2 ILE D 110 ? GLN D 128 ? ILE D 110 GLN D 128 1 ? 19 
HELX_P HELX_P66 AH3 GLY D 143 ? TYR D 161 ? GLY D 143 TYR D 161 1 ? 19 
HELX_P HELX_P67 AH4 VAL D 182 ? SER D 198 ? VAL D 182 SER D 198 1 ? 17 
HELX_P HELX_P68 AH5 ASP D 205 ? ASN D 216 ? ASP D 205 ASN D 216 1 ? 12 
HELX_P HELX_P69 AH6 THR D 223 ? PHE D 244 ? THR D 223 PHE D 244 1 ? 22 
HELX_P HELX_P70 AH7 ASP D 251 ? VAL D 260 ? ASP D 251 VAL D 260 1 ? 10 
HELX_P HELX_P71 AH8 SER D 277 ? TYR D 282 ? SER D 277 TYR D 282 1 ? 6  
HELX_P HELX_P72 AH9 SER D 287 ? GLU D 297 ? SER D 287 GLU D 297 1 ? 11 
HELX_P HELX_P73 AI1 ASP D 306 ? GLY D 310 ? ASP D 306 GLY D 310 5 ? 5  
HELX_P HELX_P74 AI2 VAL D 324 ? LYS D 338 ? VAL D 324 LYS D 338 1 ? 15 
HELX_P HELX_P75 AI3 ALA D 383 ? LYS D 401 ? ALA D 383 LYS D 401 1 ? 19 
HELX_P HELX_P76 AI4 PHE D 404 ? GLU D 411 ? PHE D 404 GLU D 411 1 ? 8  
HELX_P HELX_P77 AI5 GLU D 414 ? GLY D 436 ? GLU D 414 GLY D 436 1 ? 23 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
metalc1 metalc ? ? C GLU 71 OE2 ? ? ? 1_555 H MG . MG ? ? A GLU 71  A MG 502 1_555 ? ? ? ? ? ? ? 2.387 ? ? 
metalc2 metalc ? ? G GTP .  O1G ? ? ? 1_555 H MG . MG ? ? A GTP 501 A MG 502 1_555 ? ? ? ? ? ? ? 2.004 ? ? 
metalc3 metalc ? ? G GTP .  O2B ? ? ? 1_555 H MG . MG ? ? A GTP 501 A MG 502 1_555 ? ? ? ? ? ? ? 1.996 ? ? 
metalc4 metalc ? ? D GLU 71 OE2 ? ? ? 1_555 J MG . MG ? ? D GLU 71  D MG 502 1_555 ? ? ? ? ? ? ? 2.030 ? ? 
metalc5 metalc ? ? I GTP .  O1G ? ? ? 1_555 J MG . MG ? ? D GTP 501 D MG 502 1_555 ? ? ? ? ? ? ? 1.970 ? ? 
metalc6 metalc ? ? I GTP .  O2G ? ? ? 1_555 J MG . MG ? ? D GTP 501 D MG 502 1_555 ? ? ? ? ? ? ? 2.999 ? ? 
metalc7 metalc ? ? I GTP .  O3B ? ? ? 1_555 J MG . MG ? ? D GTP 501 D MG 502 1_555 ? ? ? ? ? ? ? 2.960 ? ? 
metalc8 metalc ? ? I GTP .  O2B ? ? ? 1_555 J MG . MG ? ? D GTP 501 D MG 502 1_555 ? ? ? ? ? ? ? 2.024 ? ? 
# 
_struct_conn_type.id          metalc 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1  OE2 ? C GLU 71 ? A GLU 71  ? 1_555 MG ? H MG . ? A MG 502 ? 1_555 O1G ? G GTP . ? A GTP 501 ? 1_555 98.9  ? 
2  OE2 ? C GLU 71 ? A GLU 71  ? 1_555 MG ? H MG . ? A MG 502 ? 1_555 O2B ? G GTP . ? A GTP 501 ? 1_555 143.8 ? 
3  O1G ? G GTP .  ? A GTP 501 ? 1_555 MG ? H MG . ? A MG 502 ? 1_555 O2B ? G GTP . ? A GTP 501 ? 1_555 91.4  ? 
4  OE2 ? D GLU 71 ? D GLU 71  ? 1_555 MG ? J MG . ? D MG 502 ? 1_555 O1G ? I GTP . ? D GTP 501 ? 1_555 127.0 ? 
5  OE2 ? D GLU 71 ? D GLU 71  ? 1_555 MG ? J MG . ? D MG 502 ? 1_555 O2G ? I GTP . ? D GTP 501 ? 1_555 123.4 ? 
6  O1G ? I GTP .  ? D GTP 501 ? 1_555 MG ? J MG . ? D MG 502 ? 1_555 O2G ? I GTP . ? D GTP 501 ? 1_555 55.3  ? 
7  OE2 ? D GLU 71 ? D GLU 71  ? 1_555 MG ? J MG . ? D MG 502 ? 1_555 O3B ? I GTP . ? D GTP 501 ? 1_555 170.5 ? 
8  O1G ? I GTP .  ? D GTP 501 ? 1_555 MG ? J MG . ? D MG 502 ? 1_555 O3B ? I GTP . ? D GTP 501 ? 1_555 57.5  ? 
9  O2G ? I GTP .  ? D GTP 501 ? 1_555 MG ? J MG . ? D MG 502 ? 1_555 O3B ? I GTP . ? D GTP 501 ? 1_555 50.3  ? 
10 OE2 ? D GLU 71 ? D GLU 71  ? 1_555 MG ? J MG . ? D MG 502 ? 1_555 O2B ? I GTP . ? D GTP 501 ? 1_555 127.4 ? 
11 O1G ? I GTP .  ? D GTP 501 ? 1_555 MG ? J MG . ? D MG 502 ? 1_555 O2B ? I GTP . ? D GTP 501 ? 1_555 88.2  ? 
12 O2G ? I GTP .  ? D GTP 501 ? 1_555 MG ? J MG . ? D MG 502 ? 1_555 O2B ? I GTP . ? D GTP 501 ? 1_555 108.5 ? 
13 O3B ? I GTP .  ? D GTP 501 ? 1_555 MG ? J MG . ? D MG 502 ? 1_555 O2B ? I GTP . ? D GTP 501 ? 1_555 58.1  ? 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 ALA 271 A . ? ALA 271 B PRO 272 A ? PRO 272 B 1 -4.68  
2 ALA 271 B . ? ALA 271 E PRO 272 B ? PRO 272 E 1 -3.10  
3 ALA 273 C . ? ALA 273 A PRO 274 C ? PRO 274 A 1 -10.07 
4 ALA 273 D . ? ALA 273 D PRO 274 D ? PRO 274 D 1 -3.41  
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 10 ? 
AA2 ? 2  ? 
AA3 ? 10 ? 
AA4 ? 2  ? 
AA5 ? 6  ? 
AA6 ? 2  ? 
AA7 ? 4  ? 
AA8 ? 6  ? 
AA9 ? 2  ? 
AB1 ? 4  ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2  ? parallel      
AA1 2 3  ? parallel      
AA1 3 4  ? parallel      
AA1 4 5  ? parallel      
AA1 5 6  ? parallel      
AA1 6 7  ? parallel      
AA1 7 8  ? anti-parallel 
AA1 8 9  ? anti-parallel 
AA1 9 10 ? parallel      
AA2 1 2  ? anti-parallel 
AA3 1 2  ? parallel      
AA3 2 3  ? parallel      
AA3 3 4  ? parallel      
AA3 4 5  ? parallel      
AA3 5 6  ? parallel      
AA3 6 7  ? parallel      
AA3 7 8  ? anti-parallel 
AA3 8 9  ? anti-parallel 
AA3 9 10 ? parallel      
AA4 1 2  ? anti-parallel 
AA5 1 2  ? parallel      
AA5 2 3  ? parallel      
AA5 3 4  ? parallel      
AA5 4 5  ? parallel      
AA5 5 6  ? parallel      
AA6 1 2  ? anti-parallel 
AA7 1 2  ? anti-parallel 
AA7 2 3  ? anti-parallel 
AA7 3 4  ? parallel      
AA8 1 2  ? parallel      
AA8 2 3  ? parallel      
AA8 3 4  ? parallel      
AA8 4 5  ? parallel      
AA8 5 6  ? parallel      
AA9 1 2  ? anti-parallel 
AB1 1 2  ? anti-parallel 
AB1 2 3  ? anti-parallel 
AB1 3 4  ? parallel      
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1  PHE A 90  ? PHE A 92  ? PHE B 90  PHE B 92  
AA1 2  ALA A 63  ? ASP A 67  ? ALA B 63  ASP B 67  
AA1 3  GLU A 3   ? ALA A 9   ? GLU B 3   ALA B 9   
AA1 4  LEU A 130 ? SER A 138 ? LEU B 130 SER B 138 
AA1 5  ASN A 165 ? VAL A 169 ? ASN B 165 VAL B 169 
AA1 6  GLU A 198 ? ILE A 202 ? GLU B 198 ILE B 202 
AA1 7  PHE A 265 ? ALA A 271 ? PHE B 265 ALA B 271 
AA1 8  MET A 363 ? SER A 371 ? MET B 363 SER B 371 
AA1 9  TYR A 310 ? GLY A 319 ? TYR B 310 GLY B 319 
AA1 10 VAL A 349 ? CYS A 354 ? VAL B 349 CYS B 354 
AA2 1  TYR A 51  ? GLU A 53  ? TYR B 51  GLU B 53  
AA2 2  TYR A 59  ? PRO A 61  ? TYR B 59  PRO B 61  
AA3 1  PHE B 90  ? PHE B 92  ? PHE E 90  PHE E 92  
AA3 2  ALA B 63  ? ASP B 67  ? ALA E 63  ASP E 67  
AA3 3  GLU B 3   ? ALA B 9   ? GLU E 3   ALA E 9   
AA3 4  LEU B 130 ? SER B 138 ? LEU E 130 SER E 138 
AA3 5  MET B 164 ? VAL B 170 ? MET E 164 VAL E 170 
AA3 6  GLU B 198 ? ASP B 203 ? GLU E 198 ASP E 203 
AA3 7  PHE B 265 ? ALA B 271 ? PHE E 265 ALA E 271 
AA3 8  MET B 363 ? GLY B 369 ? MET E 363 GLY E 369 
AA3 9  VAL B 313 ? GLY B 319 ? VAL E 313 GLY E 319 
AA3 10 VAL B 349 ? CYS B 354 ? VAL E 349 CYS E 354 
AA4 1  TYR B 51  ? GLU B 53  ? TYR E 51  GLU E 53  
AA4 2  TYR B 59  ? PRO B 61  ? TYR E 59  PRO E 61  
AA5 1  ILE C 93  ? THR C 94  ? ILE A 93  THR A 94  
AA5 2  ALA C 65  ? ASP C 69  ? ALA A 65  ASP A 69  
AA5 3  ARG C 2   ? VAL C 9   ? ARG A 2   VAL A 9   
AA5 4  GLY C 131 ? SER C 140 ? GLY A 131 SER A 140 
AA5 5  SER C 165 ? ILE C 171 ? SER A 165 ILE A 171 
AA5 6  CYS C 200 ? VAL C 204 ? CYS A 200 VAL A 204 
AA6 1  PHE C 53  ? GLU C 55  ? PHE A 53  GLU A 55  
AA6 2  HIS C 61  ? PRO C 63  ? HIS A 61  PRO A 63  
AA7 1  TYR C 272 ? ALA C 273 ? TYR A 272 ALA A 273 
AA7 2  ARG C 373 ? THR C 381 ? ARG A 373 THR A 381 
AA7 3  TYR C 312 ? GLY C 321 ? TYR A 312 GLY A 321 
AA7 4  PHE C 351 ? ASN C 356 ? PHE A 351 ASN A 356 
AA8 1  LEU D 92  ? THR D 94  ? LEU D 92  THR D 94  
AA8 2  ALA D 65  ? ASP D 69  ? ALA D 65  ASP D 69  
AA8 3  GLU D 3   ? VAL D 9   ? GLU D 3   VAL D 9   
AA8 4  LEU D 132 ? SER D 140 ? LEU D 132 SER D 140 
AA8 5  SER D 165 ? ILE D 171 ? SER D 165 ILE D 171 
AA8 6  CYS D 200 ? VAL D 204 ? CYS D 200 VAL D 204 
AA9 1  PHE D 53  ? GLU D 55  ? PHE D 53  GLU D 55  
AA9 2  HIS D 61  ? PRO D 63  ? HIS D 61  PRO D 63  
AB1 1  TYR D 272 ? ALA D 273 ? TYR D 272 ALA D 273 
AB1 2  ARG D 373 ? THR D 381 ? ARG D 373 THR D 381 
AB1 3  TYR D 312 ? GLY D 321 ? TYR D 312 GLY D 321 
AB1 4  PHE D 351 ? ASN D 356 ? PHE D 351 ASN D 356 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2  O VAL A 91  ? O VAL B 91  N LEU A 65  ? N LEU B 65  
AA1 2 3  O VAL A 66  ? O VAL B 66  N GLN A 8   ? N GLN B 8   
AA1 3 4  N GLU A 3   ? N GLU B 3   O GLN A 131 ? O GLN B 131 
AA1 4 5  N PHE A 133 ? N PHE B 133 O ASN A 165 ? O ASN B 165 
AA1 5 6  N SER A 168 ? N SER B 168 O ILE A 202 ? O ILE B 202 
AA1 6 7  N CYS A 201 ? N CYS B 201 O PHE A 266 ? O PHE B 266 
AA1 7 8  N ALA A 271 ? N ALA B 271 O VAL A 365 ? O VAL B 365 
AA1 8 9  O ALA A 364 ? O ALA B 364 N ARG A 318 ? N ARG B 318 
AA1 9 10 N PHE A 317 ? N PHE B 317 O ALA A 352 ? O ALA B 352 
AA2 1 2  N ASN A 52  ? N ASN B 52  O VAL A 60  ? O VAL B 60  
AA3 1 2  O VAL B 91  ? O VAL E 91  N LEU B 65  ? N LEU E 65  
AA3 2 3  O VAL B 66  ? O VAL E 66  N GLN B 8   ? N GLN E 8   
AA3 3 4  N ALA B 9   ? N ALA E 9   O THR B 136 ? O THR E 136 
AA3 4 5  N LEU B 135 ? N LEU E 135 O PHE B 167 ? O PHE E 167 
AA3 5 6  N VAL B 170 ? N VAL E 170 O ILE B 202 ? O ILE E 202 
AA3 6 7  N THR B 199 ? N THR E 199 O PHE B 266 ? O PHE E 266 
AA3 7 8  N ALA B 271 ? N ALA E 271 O VAL B 365 ? O VAL E 365 
AA3 8 9  O ILE B 368 ? O ILE E 368 N ALA B 314 ? N ALA E 314 
AA3 9 10 N PHE B 317 ? N PHE E 317 O ALA B 352 ? O ALA E 352 
AA4 1 2  N ASN B 52  ? N ASN E 52  O VAL B 60  ? O VAL E 60  
AA5 1 2  O ILE C 93  ? O ILE A 93  N PHE C 67  ? N PHE A 67  
AA5 2 3  O VAL C 68  ? O VAL A 68  N HIS C 8   ? N HIS A 8   
AA5 3 4  N GLU C 3   ? N GLU A 3   O GLY C 131 ? O GLY A 131 
AA5 4 5  N PHE C 135 ? N PHE A 135 O LEU C 167 ? O LEU A 167 
AA5 5 6  N GLU C 168 ? N GLU A 168 O PHE C 202 ? O PHE A 202 
AA6 1 2  N SER C 54  ? N SER A 54  O VAL C 62  ? O VAL A 62  
AA7 1 2  N ALA C 273 ? N ALA A 273 O VAL C 375 ? O VAL A 375 
AA7 2 3  O ASN C 380 ? O ASN A 380 N ALA C 314 ? N ALA A 314 
AA7 3 4  N LEU C 317 ? N LEU A 317 O LYS C 352 ? O LYS A 352 
AA8 1 2  O ILE D 93  ? O ILE D 93  N PHE D 67  ? N PHE D 67  
AA8 2 3  O VAL D 68  ? O VAL D 68  N HIS D 8   ? N HIS D 8   
AA8 3 4  N ILE D 5   ? N ILE D 5   O LEU D 136 ? O LEU D 136 
AA8 4 5  N PHE D 135 ? N PHE D 135 O LEU D 167 ? O LEU D 167 
AA8 5 6  N GLU D 168 ? N GLU D 168 O PHE D 202 ? O PHE D 202 
AA9 1 2  N SER D 54  ? N SER D 54  O VAL D 62  ? O VAL D 62  
AB1 1 2  N ALA D 273 ? N ALA D 273 O VAL D 375 ? O VAL D 375 
AB1 2 3  O ASN D 380 ? O ASN D 380 N ALA D 314 ? N ALA D 314 
AB1 3 4  N LEU D 317 ? N LEU D 317 O LYS D 352 ? O LYS D 352 
# 
_pdbx_entry_details.entry_id                   8V2J 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     N 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 HIS E 37  ? ? -141.42 23.09  
2  1 SER E 176 ? ? -160.72 111.21 
3  1 LEU E 311 ? ? -101.56 -73.58 
4  1 ASN E 370 ? ? -93.78  50.81  
5  1 TYR A 108 ? ? -93.56  -66.86 
6  1 TYR A 161 ? ? -105.81 40.99  
7  1 HIS A 266 ? ? -142.36 46.28  
8  1 LEU A 286 ? ? 61.79   60.29  
9  1 ALA A 314 ? ? -163.26 116.71 
10 1 CYS D 200 ? ? -162.04 117.86 
11 1 ALA D 314 ? ? -160.23 110.81 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8V2J 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   Cross-correlation 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         REAL 
_em_3d_fitting.ref_protocol      'FLEXIBLE FIT' 
# 
_em_3d_fitting_list.id                            1 
_em_3d_fitting_list.3d_fitting_id                 1 
_em_3d_fitting_list.pdb_entry_id                  5N5N 
_em_3d_fitting_list.pdb_chain_id                  ? 
_em_3d_fitting_list.pdb_chain_residue_range       1-441 
_em_3d_fitting_list.details                       ? 
_em_3d_fitting_list.chain_id                      ? 
_em_3d_fitting_list.chain_residue_range           1-441 
_em_3d_fitting_list.source_name                   PDB 
_em_3d_fitting_list.type                          'experimental model' 
_em_3d_fitting_list.accession_code                5N5N 
_em_3d_fitting_list.initial_refinement_model_id   1 
# 
_em_3d_reconstruction.entry_id                    8V2J 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  2.9 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               556978 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               NATURAL 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'Dynamic alpha1B and betaI/IVb microtubule' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       '1, 2' 
# 
_em_image_scans.entry_id                8V2J 
_em_image_scans.id                      1 
_em_image_scans.number_digital_images   ? 
_em_image_scans.details                 ? 
_em_image_scans.scanner_model           ? 
_em_image_scans.sampling_size           ? 
_em_image_scans.od_range                ? 
_em_image_scans.quant_bit_size          ? 
_em_image_scans.citation_id             ? 
_em_image_scans.dimension_height        ? 
_em_image_scans.dimension_width         ? 
_em_image_scans.frames_per_image        21 
_em_image_scans.image_recording_id      1 
_em_image_scans.used_frames_per_image   1-21 
# 
_em_imaging.entry_id                        8V2J 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      2.7 
_em_imaging.nominal_defocus_min             600 
_em_imaging.nominal_defocus_max             2400 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           105000 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             'COMA FREE' 
_em_imaging.c2_aperture_diameter            70 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_sample_support.id               1 
_em_sample_support.film_material    ? 
_em_sample_support.method           ? 
_em_sample_support.grid_material    GOLD 
_em_sample_support.grid_mesh_size   300 
_em_sample_support.grid_type        C-flat-1.2/1.3 
_em_sample_support.details          ? 
_em_sample_support.specimen_id      1 
_em_sample_support.citation_id      ? 
# 
_em_vitrification.entry_id              8V2J 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              100 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   303 
_em_vitrification.instrument            'LEICA EM GP' 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               
'5 ul of microtubules were applied to glow-discharged cryo-EM grid and allowed to absorb for 30 sec.' 
# 
_em_experiment.entry_id                8V2J 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       FILAMENT 
_em_experiment.entity_assembly_id      1 
# 
_em_single_particle_entity.entry_id              8V2J 
_em_single_particle_entity.id                    1 
_em_single_particle_entity.image_processing_id   1 
_em_single_particle_entity.point_symmetry        C1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 B ALA 430 ? A ALA 430 
2  1 Y 1 B GLU 431 ? A GLU 431 
3  1 Y 1 B GLU 432 ? A GLU 432 
4  1 Y 1 B GLU 433 ? A GLU 433 
5  1 Y 1 B GLU 434 ? A GLU 434 
6  1 Y 1 B ASP 435 ? A ASP 435 
7  1 Y 1 B PHE 436 ? A PHE 436 
8  1 Y 1 B GLY 437 ? A GLY 437 
9  1 Y 1 B GLU 438 ? A GLU 438 
10 1 Y 1 B GLU 439 ? A GLU 439 
11 1 Y 1 B ALA 440 ? A ALA 440 
12 1 Y 1 B GLU 441 ? A GLU 441 
13 1 Y 1 B GLU 442 ? A GLU 442 
14 1 Y 1 B GLU 443 ? A GLU 443 
15 1 Y 1 B ALA 444 ? A ALA 444 
16 1 Y 1 E ALA 430 ? B ALA 430 
17 1 Y 1 E GLU 431 ? B GLU 431 
18 1 Y 1 E GLU 432 ? B GLU 432 
19 1 Y 1 E GLU 433 ? B GLU 433 
20 1 Y 1 E GLU 434 ? B GLU 434 
21 1 Y 1 E ASP 435 ? B ASP 435 
22 1 Y 1 E PHE 436 ? B PHE 436 
23 1 Y 1 E GLY 437 ? B GLY 437 
24 1 Y 1 E GLU 438 ? B GLU 438 
25 1 Y 1 E GLU 439 ? B GLU 439 
26 1 Y 1 E ALA 440 ? B ALA 440 
27 1 Y 1 E GLU 441 ? B GLU 441 
28 1 Y 1 E GLU 442 ? B GLU 442 
29 1 Y 1 E GLU 443 ? B GLU 443 
30 1 Y 1 E ALA 444 ? B ALA 444 
31 1 Y 1 A ASP 39  ? C ASP 39  
32 1 Y 1 A LYS 40  ? C LYS 40  
33 1 Y 1 A THR 41  ? C THR 41  
34 1 Y 1 A ILE 42  ? C ILE 42  
35 1 Y 1 A GLY 442 ? C GLY 442 
36 1 Y 1 A GLU 443 ? C GLU 443 
37 1 Y 1 A GLY 444 ? C GLY 444 
38 1 Y 1 A GLU 445 ? C GLU 445 
39 1 Y 1 A GLU 446 ? C GLU 446 
40 1 Y 1 A GLU 447 ? C GLU 447 
41 1 Y 1 A GLY 448 ? C GLY 448 
42 1 Y 1 A GLU 449 ? C GLU 449 
43 1 Y 1 A GLU 450 ? C GLU 450 
44 1 Y 1 A TYR 451 ? C TYR 451 
45 1 Y 1 D ASP 39  ? D ASP 39  
46 1 Y 1 D LYS 40  ? D LYS 40  
47 1 Y 1 D THR 41  ? D THR 41  
48 1 Y 1 D ILE 42  ? D ILE 42  
49 1 Y 1 D GLY 442 ? D GLY 442 
50 1 Y 1 D GLU 443 ? D GLU 443 
51 1 Y 1 D GLY 444 ? D GLY 444 
52 1 Y 1 D GLU 445 ? D GLU 445 
53 1 Y 1 D GLU 446 ? D GLU 446 
54 1 Y 1 D GLU 447 ? D GLU 447 
55 1 Y 1 D GLY 448 ? D GLY 448 
56 1 Y 1 D GLU 449 ? D GLU 449 
57 1 Y 1 D GLU 450 ? D GLU 450 
58 1 Y 1 D TYR 451 ? D TYR 451 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N      N  N N 1   
ALA CA     C  N S 2   
ALA C      C  N N 3   
ALA O      O  N N 4   
ALA CB     C  N N 5   
ALA OXT    O  N N 6   
ALA H      H  N N 7   
ALA H2     H  N N 8   
ALA HA     H  N N 9   
ALA HB1    H  N N 10  
ALA HB2    H  N N 11  
ALA HB3    H  N N 12  
ALA HXT    H  N N 13  
ARG N      N  N N 14  
ARG CA     C  N S 15  
ARG C      C  N N 16  
ARG O      O  N N 17  
ARG CB     C  N N 18  
ARG CG     C  N N 19  
ARG CD     C  N N 20  
ARG NE     N  N N 21  
ARG CZ     C  N N 22  
ARG NH1    N  N N 23  
ARG NH2    N  N N 24  
ARG OXT    O  N N 25  
ARG H      H  N N 26  
ARG H2     H  N N 27  
ARG HA     H  N N 28  
ARG HB2    H  N N 29  
ARG HB3    H  N N 30  
ARG HG2    H  N N 31  
ARG HG3    H  N N 32  
ARG HD2    H  N N 33  
ARG HD3    H  N N 34  
ARG HE     H  N N 35  
ARG HH11   H  N N 36  
ARG HH12   H  N N 37  
ARG HH21   H  N N 38  
ARG HH22   H  N N 39  
ARG HXT    H  N N 40  
ASN N      N  N N 41  
ASN CA     C  N S 42  
ASN C      C  N N 43  
ASN O      O  N N 44  
ASN CB     C  N N 45  
ASN CG     C  N N 46  
ASN OD1    O  N N 47  
ASN ND2    N  N N 48  
ASN OXT    O  N N 49  
ASN H      H  N N 50  
ASN H2     H  N N 51  
ASN HA     H  N N 52  
ASN HB2    H  N N 53  
ASN HB3    H  N N 54  
ASN HD21   H  N N 55  
ASN HD22   H  N N 56  
ASN HXT    H  N N 57  
ASP N      N  N N 58  
ASP CA     C  N S 59  
ASP C      C  N N 60  
ASP O      O  N N 61  
ASP CB     C  N N 62  
ASP CG     C  N N 63  
ASP OD1    O  N N 64  
ASP OD2    O  N N 65  
ASP OXT    O  N N 66  
ASP H      H  N N 67  
ASP H2     H  N N 68  
ASP HA     H  N N 69  
ASP HB2    H  N N 70  
ASP HB3    H  N N 71  
ASP HD2    H  N N 72  
ASP HXT    H  N N 73  
CYS N      N  N N 74  
CYS CA     C  N R 75  
CYS C      C  N N 76  
CYS O      O  N N 77  
CYS CB     C  N N 78  
CYS SG     S  N N 79  
CYS OXT    O  N N 80  
CYS H      H  N N 81  
CYS H2     H  N N 82  
CYS HA     H  N N 83  
CYS HB2    H  N N 84  
CYS HB3    H  N N 85  
CYS HG     H  N N 86  
CYS HXT    H  N N 87  
GDP PB     P  N N 88  
GDP O1B    O  N N 89  
GDP O2B    O  N N 90  
GDP O3B    O  N N 91  
GDP O3A    O  N N 92  
GDP PA     P  N N 93  
GDP O1A    O  N N 94  
GDP O2A    O  N N 95  
GDP "O5'"  O  N N 96  
GDP "C5'"  C  N N 97  
GDP "C4'"  C  N R 98  
GDP "O4'"  O  N N 99  
GDP "C3'"  C  N S 100 
GDP "O3'"  O  N N 101 
GDP "C2'"  C  N R 102 
GDP "O2'"  O  N N 103 
GDP "C1'"  C  N R 104 
GDP N9     N  Y N 105 
GDP C8     C  Y N 106 
GDP N7     N  Y N 107 
GDP C5     C  Y N 108 
GDP C6     C  N N 109 
GDP O6     O  N N 110 
GDP N1     N  N N 111 
GDP C2     C  N N 112 
GDP N2     N  N N 113 
GDP N3     N  N N 114 
GDP C4     C  Y N 115 
GDP HOB2   H  N N 116 
GDP HOB3   H  N N 117 
GDP HOA2   H  N N 118 
GDP "H5'"  H  N N 119 
GDP "H5''" H  N N 120 
GDP "H4'"  H  N N 121 
GDP "H3'"  H  N N 122 
GDP "HO3'" H  N N 123 
GDP "H2'"  H  N N 124 
GDP "HO2'" H  N N 125 
GDP "H1'"  H  N N 126 
GDP H8     H  N N 127 
GDP HN1    H  N N 128 
GDP HN21   H  N N 129 
GDP HN22   H  N N 130 
GLN N      N  N N 131 
GLN CA     C  N S 132 
GLN C      C  N N 133 
GLN O      O  N N 134 
GLN CB     C  N N 135 
GLN CG     C  N N 136 
GLN CD     C  N N 137 
GLN OE1    O  N N 138 
GLN NE2    N  N N 139 
GLN OXT    O  N N 140 
GLN H      H  N N 141 
GLN H2     H  N N 142 
GLN HA     H  N N 143 
GLN HB2    H  N N 144 
GLN HB3    H  N N 145 
GLN HG2    H  N N 146 
GLN HG3    H  N N 147 
GLN HE21   H  N N 148 
GLN HE22   H  N N 149 
GLN HXT    H  N N 150 
GLU N      N  N N 151 
GLU CA     C  N S 152 
GLU C      C  N N 153 
GLU O      O  N N 154 
GLU CB     C  N N 155 
GLU CG     C  N N 156 
GLU CD     C  N N 157 
GLU OE1    O  N N 158 
GLU OE2    O  N N 159 
GLU OXT    O  N N 160 
GLU H      H  N N 161 
GLU H2     H  N N 162 
GLU HA     H  N N 163 
GLU HB2    H  N N 164 
GLU HB3    H  N N 165 
GLU HG2    H  N N 166 
GLU HG3    H  N N 167 
GLU HE2    H  N N 168 
GLU HXT    H  N N 169 
GLY N      N  N N 170 
GLY CA     C  N N 171 
GLY C      C  N N 172 
GLY O      O  N N 173 
GLY OXT    O  N N 174 
GLY H      H  N N 175 
GLY H2     H  N N 176 
GLY HA2    H  N N 177 
GLY HA3    H  N N 178 
GLY HXT    H  N N 179 
GTP PG     P  N N 180 
GTP O1G    O  N N 181 
GTP O2G    O  N N 182 
GTP O3G    O  N N 183 
GTP O3B    O  N N 184 
GTP PB     P  N N 185 
GTP O1B    O  N N 186 
GTP O2B    O  N N 187 
GTP O3A    O  N N 188 
GTP PA     P  N N 189 
GTP O1A    O  N N 190 
GTP O2A    O  N N 191 
GTP "O5'"  O  N N 192 
GTP "C5'"  C  N N 193 
GTP "C4'"  C  N R 194 
GTP "O4'"  O  N N 195 
GTP "C3'"  C  N S 196 
GTP "O3'"  O  N N 197 
GTP "C2'"  C  N R 198 
GTP "O2'"  O  N N 199 
GTP "C1'"  C  N R 200 
GTP N9     N  Y N 201 
GTP C8     C  Y N 202 
GTP N7     N  Y N 203 
GTP C5     C  Y N 204 
GTP C6     C  N N 205 
GTP O6     O  N N 206 
GTP N1     N  N N 207 
GTP C2     C  N N 208 
GTP N2     N  N N 209 
GTP N3     N  N N 210 
GTP C4     C  Y N 211 
GTP HOG2   H  N N 212 
GTP HOG3   H  N N 213 
GTP HOB2   H  N N 214 
GTP HOA2   H  N N 215 
GTP "H5'"  H  N N 216 
GTP "H5''" H  N N 217 
GTP "H4'"  H  N N 218 
GTP "H3'"  H  N N 219 
GTP "HO3'" H  N N 220 
GTP "H2'"  H  N N 221 
GTP "HO2'" H  N N 222 
GTP "H1'"  H  N N 223 
GTP H8     H  N N 224 
GTP HN1    H  N N 225 
GTP HN21   H  N N 226 
GTP HN22   H  N N 227 
HIS N      N  N N 228 
HIS CA     C  N S 229 
HIS C      C  N N 230 
HIS O      O  N N 231 
HIS CB     C  N N 232 
HIS CG     C  Y N 233 
HIS ND1    N  Y N 234 
HIS CD2    C  Y N 235 
HIS CE1    C  Y N 236 
HIS NE2    N  Y N 237 
HIS OXT    O  N N 238 
HIS H      H  N N 239 
HIS H2     H  N N 240 
HIS HA     H  N N 241 
HIS HB2    H  N N 242 
HIS HB3    H  N N 243 
HIS HD1    H  N N 244 
HIS HD2    H  N N 245 
HIS HE1    H  N N 246 
HIS HE2    H  N N 247 
HIS HXT    H  N N 248 
ILE N      N  N N 249 
ILE CA     C  N S 250 
ILE C      C  N N 251 
ILE O      O  N N 252 
ILE CB     C  N S 253 
ILE CG1    C  N N 254 
ILE CG2    C  N N 255 
ILE CD1    C  N N 256 
ILE OXT    O  N N 257 
ILE H      H  N N 258 
ILE H2     H  N N 259 
ILE HA     H  N N 260 
ILE HB     H  N N 261 
ILE HG12   H  N N 262 
ILE HG13   H  N N 263 
ILE HG21   H  N N 264 
ILE HG22   H  N N 265 
ILE HG23   H  N N 266 
ILE HD11   H  N N 267 
ILE HD12   H  N N 268 
ILE HD13   H  N N 269 
ILE HXT    H  N N 270 
LEU N      N  N N 271 
LEU CA     C  N S 272 
LEU C      C  N N 273 
LEU O      O  N N 274 
LEU CB     C  N N 275 
LEU CG     C  N N 276 
LEU CD1    C  N N 277 
LEU CD2    C  N N 278 
LEU OXT    O  N N 279 
LEU H      H  N N 280 
LEU H2     H  N N 281 
LEU HA     H  N N 282 
LEU HB2    H  N N 283 
LEU HB3    H  N N 284 
LEU HG     H  N N 285 
LEU HD11   H  N N 286 
LEU HD12   H  N N 287 
LEU HD13   H  N N 288 
LEU HD21   H  N N 289 
LEU HD22   H  N N 290 
LEU HD23   H  N N 291 
LEU HXT    H  N N 292 
LYS N      N  N N 293 
LYS CA     C  N S 294 
LYS C      C  N N 295 
LYS O      O  N N 296 
LYS CB     C  N N 297 
LYS CG     C  N N 298 
LYS CD     C  N N 299 
LYS CE     C  N N 300 
LYS NZ     N  N N 301 
LYS OXT    O  N N 302 
LYS H      H  N N 303 
LYS H2     H  N N 304 
LYS HA     H  N N 305 
LYS HB2    H  N N 306 
LYS HB3    H  N N 307 
LYS HG2    H  N N 308 
LYS HG3    H  N N 309 
LYS HD2    H  N N 310 
LYS HD3    H  N N 311 
LYS HE2    H  N N 312 
LYS HE3    H  N N 313 
LYS HZ1    H  N N 314 
LYS HZ2    H  N N 315 
LYS HZ3    H  N N 316 
LYS HXT    H  N N 317 
MET N      N  N N 318 
MET CA     C  N S 319 
MET C      C  N N 320 
MET O      O  N N 321 
MET CB     C  N N 322 
MET CG     C  N N 323 
MET SD     S  N N 324 
MET CE     C  N N 325 
MET OXT    O  N N 326 
MET H      H  N N 327 
MET H2     H  N N 328 
MET HA     H  N N 329 
MET HB2    H  N N 330 
MET HB3    H  N N 331 
MET HG2    H  N N 332 
MET HG3    H  N N 333 
MET HE1    H  N N 334 
MET HE2    H  N N 335 
MET HE3    H  N N 336 
MET HXT    H  N N 337 
MG  MG     MG N N 338 
PHE N      N  N N 339 
PHE CA     C  N S 340 
PHE C      C  N N 341 
PHE O      O  N N 342 
PHE CB     C  N N 343 
PHE CG     C  Y N 344 
PHE CD1    C  Y N 345 
PHE CD2    C  Y N 346 
PHE CE1    C  Y N 347 
PHE CE2    C  Y N 348 
PHE CZ     C  Y N 349 
PHE OXT    O  N N 350 
PHE H      H  N N 351 
PHE H2     H  N N 352 
PHE HA     H  N N 353 
PHE HB2    H  N N 354 
PHE HB3    H  N N 355 
PHE HD1    H  N N 356 
PHE HD2    H  N N 357 
PHE HE1    H  N N 358 
PHE HE2    H  N N 359 
PHE HZ     H  N N 360 
PHE HXT    H  N N 361 
PRO N      N  N N 362 
PRO CA     C  N S 363 
PRO C      C  N N 364 
PRO O      O  N N 365 
PRO CB     C  N N 366 
PRO CG     C  N N 367 
PRO CD     C  N N 368 
PRO OXT    O  N N 369 
PRO H      H  N N 370 
PRO HA     H  N N 371 
PRO HB2    H  N N 372 
PRO HB3    H  N N 373 
PRO HG2    H  N N 374 
PRO HG3    H  N N 375 
PRO HD2    H  N N 376 
PRO HD3    H  N N 377 
PRO HXT    H  N N 378 
SER N      N  N N 379 
SER CA     C  N S 380 
SER C      C  N N 381 
SER O      O  N N 382 
SER CB     C  N N 383 
SER OG     O  N N 384 
SER OXT    O  N N 385 
SER H      H  N N 386 
SER H2     H  N N 387 
SER HA     H  N N 388 
SER HB2    H  N N 389 
SER HB3    H  N N 390 
SER HG     H  N N 391 
SER HXT    H  N N 392 
THR N      N  N N 393 
THR CA     C  N S 394 
THR C      C  N N 395 
THR O      O  N N 396 
THR CB     C  N R 397 
THR OG1    O  N N 398 
THR CG2    C  N N 399 
THR OXT    O  N N 400 
THR H      H  N N 401 
THR H2     H  N N 402 
THR HA     H  N N 403 
THR HB     H  N N 404 
THR HG1    H  N N 405 
THR HG21   H  N N 406 
THR HG22   H  N N 407 
THR HG23   H  N N 408 
THR HXT    H  N N 409 
TRP N      N  N N 410 
TRP CA     C  N S 411 
TRP C      C  N N 412 
TRP O      O  N N 413 
TRP CB     C  N N 414 
TRP CG     C  Y N 415 
TRP CD1    C  Y N 416 
TRP CD2    C  Y N 417 
TRP NE1    N  Y N 418 
TRP CE2    C  Y N 419 
TRP CE3    C  Y N 420 
TRP CZ2    C  Y N 421 
TRP CZ3    C  Y N 422 
TRP CH2    C  Y N 423 
TRP OXT    O  N N 424 
TRP H      H  N N 425 
TRP H2     H  N N 426 
TRP HA     H  N N 427 
TRP HB2    H  N N 428 
TRP HB3    H  N N 429 
TRP HD1    H  N N 430 
TRP HE1    H  N N 431 
TRP HE3    H  N N 432 
TRP HZ2    H  N N 433 
TRP HZ3    H  N N 434 
TRP HH2    H  N N 435 
TRP HXT    H  N N 436 
TYR N      N  N N 437 
TYR CA     C  N S 438 
TYR C      C  N N 439 
TYR O      O  N N 440 
TYR CB     C  N N 441 
TYR CG     C  Y N 442 
TYR CD1    C  Y N 443 
TYR CD2    C  Y N 444 
TYR CE1    C  Y N 445 
TYR CE2    C  Y N 446 
TYR CZ     C  Y N 447 
TYR OH     O  N N 448 
TYR OXT    O  N N 449 
TYR H      H  N N 450 
TYR H2     H  N N 451 
TYR HA     H  N N 452 
TYR HB2    H  N N 453 
TYR HB3    H  N N 454 
TYR HD1    H  N N 455 
TYR HD2    H  N N 456 
TYR HE1    H  N N 457 
TYR HE2    H  N N 458 
TYR HH     H  N N 459 
TYR HXT    H  N N 460 
VAL N      N  N N 461 
VAL CA     C  N S 462 
VAL C      C  N N 463 
VAL O      O  N N 464 
VAL CB     C  N N 465 
VAL CG1    C  N N 466 
VAL CG2    C  N N 467 
VAL OXT    O  N N 468 
VAL H      H  N N 469 
VAL H2     H  N N 470 
VAL HA     H  N N 471 
VAL HB     H  N N 472 
VAL HG11   H  N N 473 
VAL HG12   H  N N 474 
VAL HG13   H  N N 475 
VAL HG21   H  N N 476 
VAL HG22   H  N N 477 
VAL HG23   H  N N 478 
VAL HXT    H  N N 479 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N     CA     sing N N 1   
ALA N     H      sing N N 2   
ALA N     H2     sing N N 3   
ALA CA    C      sing N N 4   
ALA CA    CB     sing N N 5   
ALA CA    HA     sing N N 6   
ALA C     O      doub N N 7   
ALA C     OXT    sing N N 8   
ALA CB    HB1    sing N N 9   
ALA CB    HB2    sing N N 10  
ALA CB    HB3    sing N N 11  
ALA OXT   HXT    sing N N 12  
ARG N     CA     sing N N 13  
ARG N     H      sing N N 14  
ARG N     H2     sing N N 15  
ARG CA    C      sing N N 16  
ARG CA    CB     sing N N 17  
ARG CA    HA     sing N N 18  
ARG C     O      doub N N 19  
ARG C     OXT    sing N N 20  
ARG CB    CG     sing N N 21  
ARG CB    HB2    sing N N 22  
ARG CB    HB3    sing N N 23  
ARG CG    CD     sing N N 24  
ARG CG    HG2    sing N N 25  
ARG CG    HG3    sing N N 26  
ARG CD    NE     sing N N 27  
ARG CD    HD2    sing N N 28  
ARG CD    HD3    sing N N 29  
ARG NE    CZ     sing N N 30  
ARG NE    HE     sing N N 31  
ARG CZ    NH1    sing N N 32  
ARG CZ    NH2    doub N N 33  
ARG NH1   HH11   sing N N 34  
ARG NH1   HH12   sing N N 35  
ARG NH2   HH21   sing N N 36  
ARG NH2   HH22   sing N N 37  
ARG OXT   HXT    sing N N 38  
ASN N     CA     sing N N 39  
ASN N     H      sing N N 40  
ASN N     H2     sing N N 41  
ASN CA    C      sing N N 42  
ASN CA    CB     sing N N 43  
ASN CA    HA     sing N N 44  
ASN C     O      doub N N 45  
ASN C     OXT    sing N N 46  
ASN CB    CG     sing N N 47  
ASN CB    HB2    sing N N 48  
ASN CB    HB3    sing N N 49  
ASN CG    OD1    doub N N 50  
ASN CG    ND2    sing N N 51  
ASN ND2   HD21   sing N N 52  
ASN ND2   HD22   sing N N 53  
ASN OXT   HXT    sing N N 54  
ASP N     CA     sing N N 55  
ASP N     H      sing N N 56  
ASP N     H2     sing N N 57  
ASP CA    C      sing N N 58  
ASP CA    CB     sing N N 59  
ASP CA    HA     sing N N 60  
ASP C     O      doub N N 61  
ASP C     OXT    sing N N 62  
ASP CB    CG     sing N N 63  
ASP CB    HB2    sing N N 64  
ASP CB    HB3    sing N N 65  
ASP CG    OD1    doub N N 66  
ASP CG    OD2    sing N N 67  
ASP OD2   HD2    sing N N 68  
ASP OXT   HXT    sing N N 69  
CYS N     CA     sing N N 70  
CYS N     H      sing N N 71  
CYS N     H2     sing N N 72  
CYS CA    C      sing N N 73  
CYS CA    CB     sing N N 74  
CYS CA    HA     sing N N 75  
CYS C     O      doub N N 76  
CYS C     OXT    sing N N 77  
CYS CB    SG     sing N N 78  
CYS CB    HB2    sing N N 79  
CYS CB    HB3    sing N N 80  
CYS SG    HG     sing N N 81  
CYS OXT   HXT    sing N N 82  
GDP PB    O1B    doub N N 83  
GDP PB    O2B    sing N N 84  
GDP PB    O3B    sing N N 85  
GDP PB    O3A    sing N N 86  
GDP O2B   HOB2   sing N N 87  
GDP O3B   HOB3   sing N N 88  
GDP O3A   PA     sing N N 89  
GDP PA    O1A    doub N N 90  
GDP PA    O2A    sing N N 91  
GDP PA    "O5'"  sing N N 92  
GDP O2A   HOA2   sing N N 93  
GDP "O5'" "C5'"  sing N N 94  
GDP "C5'" "C4'"  sing N N 95  
GDP "C5'" "H5'"  sing N N 96  
GDP "C5'" "H5''" sing N N 97  
GDP "C4'" "O4'"  sing N N 98  
GDP "C4'" "C3'"  sing N N 99  
GDP "C4'" "H4'"  sing N N 100 
GDP "O4'" "C1'"  sing N N 101 
GDP "C3'" "O3'"  sing N N 102 
GDP "C3'" "C2'"  sing N N 103 
GDP "C3'" "H3'"  sing N N 104 
GDP "O3'" "HO3'" sing N N 105 
GDP "C2'" "O2'"  sing N N 106 
GDP "C2'" "C1'"  sing N N 107 
GDP "C2'" "H2'"  sing N N 108 
GDP "O2'" "HO2'" sing N N 109 
GDP "C1'" N9     sing N N 110 
GDP "C1'" "H1'"  sing N N 111 
GDP N9    C8     sing Y N 112 
GDP N9    C4     sing Y N 113 
GDP C8    N7     doub Y N 114 
GDP C8    H8     sing N N 115 
GDP N7    C5     sing Y N 116 
GDP C5    C6     sing N N 117 
GDP C5    C4     doub Y N 118 
GDP C6    O6     doub N N 119 
GDP C6    N1     sing N N 120 
GDP N1    C2     sing N N 121 
GDP N1    HN1    sing N N 122 
GDP C2    N2     sing N N 123 
GDP C2    N3     doub N N 124 
GDP N2    HN21   sing N N 125 
GDP N2    HN22   sing N N 126 
GDP N3    C4     sing N N 127 
GLN N     CA     sing N N 128 
GLN N     H      sing N N 129 
GLN N     H2     sing N N 130 
GLN CA    C      sing N N 131 
GLN CA    CB     sing N N 132 
GLN CA    HA     sing N N 133 
GLN C     O      doub N N 134 
GLN C     OXT    sing N N 135 
GLN CB    CG     sing N N 136 
GLN CB    HB2    sing N N 137 
GLN CB    HB3    sing N N 138 
GLN CG    CD     sing N N 139 
GLN CG    HG2    sing N N 140 
GLN CG    HG3    sing N N 141 
GLN CD    OE1    doub N N 142 
GLN CD    NE2    sing N N 143 
GLN NE2   HE21   sing N N 144 
GLN NE2   HE22   sing N N 145 
GLN OXT   HXT    sing N N 146 
GLU N     CA     sing N N 147 
GLU N     H      sing N N 148 
GLU N     H2     sing N N 149 
GLU CA    C      sing N N 150 
GLU CA    CB     sing N N 151 
GLU CA    HA     sing N N 152 
GLU C     O      doub N N 153 
GLU C     OXT    sing N N 154 
GLU CB    CG     sing N N 155 
GLU CB    HB2    sing N N 156 
GLU CB    HB3    sing N N 157 
GLU CG    CD     sing N N 158 
GLU CG    HG2    sing N N 159 
GLU CG    HG3    sing N N 160 
GLU CD    OE1    doub N N 161 
GLU CD    OE2    sing N N 162 
GLU OE2   HE2    sing N N 163 
GLU OXT   HXT    sing N N 164 
GLY N     CA     sing N N 165 
GLY N     H      sing N N 166 
GLY N     H2     sing N N 167 
GLY CA    C      sing N N 168 
GLY CA    HA2    sing N N 169 
GLY CA    HA3    sing N N 170 
GLY C     O      doub N N 171 
GLY C     OXT    sing N N 172 
GLY OXT   HXT    sing N N 173 
GTP PG    O1G    doub N N 174 
GTP PG    O2G    sing N N 175 
GTP PG    O3G    sing N N 176 
GTP PG    O3B    sing N N 177 
GTP O2G   HOG2   sing N N 178 
GTP O3G   HOG3   sing N N 179 
GTP O3B   PB     sing N N 180 
GTP PB    O1B    doub N N 181 
GTP PB    O2B    sing N N 182 
GTP PB    O3A    sing N N 183 
GTP O2B   HOB2   sing N N 184 
GTP O3A   PA     sing N N 185 
GTP PA    O1A    doub N N 186 
GTP PA    O2A    sing N N 187 
GTP PA    "O5'"  sing N N 188 
GTP O2A   HOA2   sing N N 189 
GTP "O5'" "C5'"  sing N N 190 
GTP "C5'" "C4'"  sing N N 191 
GTP "C5'" "H5'"  sing N N 192 
GTP "C5'" "H5''" sing N N 193 
GTP "C4'" "O4'"  sing N N 194 
GTP "C4'" "C3'"  sing N N 195 
GTP "C4'" "H4'"  sing N N 196 
GTP "O4'" "C1'"  sing N N 197 
GTP "C3'" "O3'"  sing N N 198 
GTP "C3'" "C2'"  sing N N 199 
GTP "C3'" "H3'"  sing N N 200 
GTP "O3'" "HO3'" sing N N 201 
GTP "C2'" "O2'"  sing N N 202 
GTP "C2'" "C1'"  sing N N 203 
GTP "C2'" "H2'"  sing N N 204 
GTP "O2'" "HO2'" sing N N 205 
GTP "C1'" N9     sing N N 206 
GTP "C1'" "H1'"  sing N N 207 
GTP N9    C8     sing Y N 208 
GTP N9    C4     sing Y N 209 
GTP C8    N7     doub Y N 210 
GTP C8    H8     sing N N 211 
GTP N7    C5     sing Y N 212 
GTP C5    C6     sing N N 213 
GTP C5    C4     doub Y N 214 
GTP C6    O6     doub N N 215 
GTP C6    N1     sing N N 216 
GTP N1    C2     sing N N 217 
GTP N1    HN1    sing N N 218 
GTP C2    N2     sing N N 219 
GTP C2    N3     doub N N 220 
GTP N2    HN21   sing N N 221 
GTP N2    HN22   sing N N 222 
GTP N3    C4     sing N N 223 
HIS N     CA     sing N N 224 
HIS N     H      sing N N 225 
HIS N     H2     sing N N 226 
HIS CA    C      sing N N 227 
HIS CA    CB     sing N N 228 
HIS CA    HA     sing N N 229 
HIS C     O      doub N N 230 
HIS C     OXT    sing N N 231 
HIS CB    CG     sing N N 232 
HIS CB    HB2    sing N N 233 
HIS CB    HB3    sing N N 234 
HIS CG    ND1    sing Y N 235 
HIS CG    CD2    doub Y N 236 
HIS ND1   CE1    doub Y N 237 
HIS ND1   HD1    sing N N 238 
HIS CD2   NE2    sing Y N 239 
HIS CD2   HD2    sing N N 240 
HIS CE1   NE2    sing Y N 241 
HIS CE1   HE1    sing N N 242 
HIS NE2   HE2    sing N N 243 
HIS OXT   HXT    sing N N 244 
ILE N     CA     sing N N 245 
ILE N     H      sing N N 246 
ILE N     H2     sing N N 247 
ILE CA    C      sing N N 248 
ILE CA    CB     sing N N 249 
ILE CA    HA     sing N N 250 
ILE C     O      doub N N 251 
ILE C     OXT    sing N N 252 
ILE CB    CG1    sing N N 253 
ILE CB    CG2    sing N N 254 
ILE CB    HB     sing N N 255 
ILE CG1   CD1    sing N N 256 
ILE CG1   HG12   sing N N 257 
ILE CG1   HG13   sing N N 258 
ILE CG2   HG21   sing N N 259 
ILE CG2   HG22   sing N N 260 
ILE CG2   HG23   sing N N 261 
ILE CD1   HD11   sing N N 262 
ILE CD1   HD12   sing N N 263 
ILE CD1   HD13   sing N N 264 
ILE OXT   HXT    sing N N 265 
LEU N     CA     sing N N 266 
LEU N     H      sing N N 267 
LEU N     H2     sing N N 268 
LEU CA    C      sing N N 269 
LEU CA    CB     sing N N 270 
LEU CA    HA     sing N N 271 
LEU C     O      doub N N 272 
LEU C     OXT    sing N N 273 
LEU CB    CG     sing N N 274 
LEU CB    HB2    sing N N 275 
LEU CB    HB3    sing N N 276 
LEU CG    CD1    sing N N 277 
LEU CG    CD2    sing N N 278 
LEU CG    HG     sing N N 279 
LEU CD1   HD11   sing N N 280 
LEU CD1   HD12   sing N N 281 
LEU CD1   HD13   sing N N 282 
LEU CD2   HD21   sing N N 283 
LEU CD2   HD22   sing N N 284 
LEU CD2   HD23   sing N N 285 
LEU OXT   HXT    sing N N 286 
LYS N     CA     sing N N 287 
LYS N     H      sing N N 288 
LYS N     H2     sing N N 289 
LYS CA    C      sing N N 290 
LYS CA    CB     sing N N 291 
LYS CA    HA     sing N N 292 
LYS C     O      doub N N 293 
LYS C     OXT    sing N N 294 
LYS CB    CG     sing N N 295 
LYS CB    HB2    sing N N 296 
LYS CB    HB3    sing N N 297 
LYS CG    CD     sing N N 298 
LYS CG    HG2    sing N N 299 
LYS CG    HG3    sing N N 300 
LYS CD    CE     sing N N 301 
LYS CD    HD2    sing N N 302 
LYS CD    HD3    sing N N 303 
LYS CE    NZ     sing N N 304 
LYS CE    HE2    sing N N 305 
LYS CE    HE3    sing N N 306 
LYS NZ    HZ1    sing N N 307 
LYS NZ    HZ2    sing N N 308 
LYS NZ    HZ3    sing N N 309 
LYS OXT   HXT    sing N N 310 
MET N     CA     sing N N 311 
MET N     H      sing N N 312 
MET N     H2     sing N N 313 
MET CA    C      sing N N 314 
MET CA    CB     sing N N 315 
MET CA    HA     sing N N 316 
MET C     O      doub N N 317 
MET C     OXT    sing N N 318 
MET CB    CG     sing N N 319 
MET CB    HB2    sing N N 320 
MET CB    HB3    sing N N 321 
MET CG    SD     sing N N 322 
MET CG    HG2    sing N N 323 
MET CG    HG3    sing N N 324 
MET SD    CE     sing N N 325 
MET CE    HE1    sing N N 326 
MET CE    HE2    sing N N 327 
MET CE    HE3    sing N N 328 
MET OXT   HXT    sing N N 329 
PHE N     CA     sing N N 330 
PHE N     H      sing N N 331 
PHE N     H2     sing N N 332 
PHE CA    C      sing N N 333 
PHE CA    CB     sing N N 334 
PHE CA    HA     sing N N 335 
PHE C     O      doub N N 336 
PHE C     OXT    sing N N 337 
PHE CB    CG     sing N N 338 
PHE CB    HB2    sing N N 339 
PHE CB    HB3    sing N N 340 
PHE CG    CD1    doub Y N 341 
PHE CG    CD2    sing Y N 342 
PHE CD1   CE1    sing Y N 343 
PHE CD1   HD1    sing N N 344 
PHE CD2   CE2    doub Y N 345 
PHE CD2   HD2    sing N N 346 
PHE CE1   CZ     doub Y N 347 
PHE CE1   HE1    sing N N 348 
PHE CE2   CZ     sing Y N 349 
PHE CE2   HE2    sing N N 350 
PHE CZ    HZ     sing N N 351 
PHE OXT   HXT    sing N N 352 
PRO N     CA     sing N N 353 
PRO N     CD     sing N N 354 
PRO N     H      sing N N 355 
PRO CA    C      sing N N 356 
PRO CA    CB     sing N N 357 
PRO CA    HA     sing N N 358 
PRO C     O      doub N N 359 
PRO C     OXT    sing N N 360 
PRO CB    CG     sing N N 361 
PRO CB    HB2    sing N N 362 
PRO CB    HB3    sing N N 363 
PRO CG    CD     sing N N 364 
PRO CG    HG2    sing N N 365 
PRO CG    HG3    sing N N 366 
PRO CD    HD2    sing N N 367 
PRO CD    HD3    sing N N 368 
PRO OXT   HXT    sing N N 369 
SER N     CA     sing N N 370 
SER N     H      sing N N 371 
SER N     H2     sing N N 372 
SER CA    C      sing N N 373 
SER CA    CB     sing N N 374 
SER CA    HA     sing N N 375 
SER C     O      doub N N 376 
SER C     OXT    sing N N 377 
SER CB    OG     sing N N 378 
SER CB    HB2    sing N N 379 
SER CB    HB3    sing N N 380 
SER OG    HG     sing N N 381 
SER OXT   HXT    sing N N 382 
THR N     CA     sing N N 383 
THR N     H      sing N N 384 
THR N     H2     sing N N 385 
THR CA    C      sing N N 386 
THR CA    CB     sing N N 387 
THR CA    HA     sing N N 388 
THR C     O      doub N N 389 
THR C     OXT    sing N N 390 
THR CB    OG1    sing N N 391 
THR CB    CG2    sing N N 392 
THR CB    HB     sing N N 393 
THR OG1   HG1    sing N N 394 
THR CG2   HG21   sing N N 395 
THR CG2   HG22   sing N N 396 
THR CG2   HG23   sing N N 397 
THR OXT   HXT    sing N N 398 
TRP N     CA     sing N N 399 
TRP N     H      sing N N 400 
TRP N     H2     sing N N 401 
TRP CA    C      sing N N 402 
TRP CA    CB     sing N N 403 
TRP CA    HA     sing N N 404 
TRP C     O      doub N N 405 
TRP C     OXT    sing N N 406 
TRP CB    CG     sing N N 407 
TRP CB    HB2    sing N N 408 
TRP CB    HB3    sing N N 409 
TRP CG    CD1    doub Y N 410 
TRP CG    CD2    sing Y N 411 
TRP CD1   NE1    sing Y N 412 
TRP CD1   HD1    sing N N 413 
TRP CD2   CE2    doub Y N 414 
TRP CD2   CE3    sing Y N 415 
TRP NE1   CE2    sing Y N 416 
TRP NE1   HE1    sing N N 417 
TRP CE2   CZ2    sing Y N 418 
TRP CE3   CZ3    doub Y N 419 
TRP CE3   HE3    sing N N 420 
TRP CZ2   CH2    doub Y N 421 
TRP CZ2   HZ2    sing N N 422 
TRP CZ3   CH2    sing Y N 423 
TRP CZ3   HZ3    sing N N 424 
TRP CH2   HH2    sing N N 425 
TRP OXT   HXT    sing N N 426 
TYR N     CA     sing N N 427 
TYR N     H      sing N N 428 
TYR N     H2     sing N N 429 
TYR CA    C      sing N N 430 
TYR CA    CB     sing N N 431 
TYR CA    HA     sing N N 432 
TYR C     O      doub N N 433 
TYR C     OXT    sing N N 434 
TYR CB    CG     sing N N 435 
TYR CB    HB2    sing N N 436 
TYR CB    HB3    sing N N 437 
TYR CG    CD1    doub Y N 438 
TYR CG    CD2    sing Y N 439 
TYR CD1   CE1    sing Y N 440 
TYR CD1   HD1    sing N N 441 
TYR CD2   CE2    doub Y N 442 
TYR CD2   HD2    sing N N 443 
TYR CE1   CZ     doub Y N 444 
TYR CE1   HE1    sing N N 445 
TYR CE2   CZ     sing Y N 446 
TYR CE2   HE2    sing N N 447 
TYR CZ    OH     sing N N 448 
TYR OH    HH     sing N N 449 
TYR OXT   HXT    sing N N 450 
VAL N     CA     sing N N 451 
VAL N     H      sing N N 452 
VAL N     H2     sing N N 453 
VAL CA    C      sing N N 454 
VAL CA    CB     sing N N 455 
VAL CA    HA     sing N N 456 
VAL C     O      doub N N 457 
VAL C     OXT    sing N N 458 
VAL CB    CG1    sing N N 459 
VAL CB    CG2    sing N N 460 
VAL CB    HB     sing N N 461 
VAL CG1   HG11   sing N N 462 
VAL CG1   HG12   sing N N 463 
VAL CG1   HG13   sing N N 464 
VAL CG2   HG21   sing N N 465 
VAL CG2   HG22   sing N N 466 
VAL CG2   HG23   sing N N 467 
VAL OXT   HXT    sing N N 468 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2023-11-22 
_em_admin.deposition_site    RCSB 
_em_admin.entry_id           8V2J 
_em_admin.last_update        2024-11-27 
_em_admin.map_release_date   2024-11-27 
_em_admin.title              'Structure of alpha1B and betaI/IVb microtubule bound to GDP' 
# 
loop_
_em_buffer_component.buffer_id 
_em_buffer_component.concentration 
_em_buffer_component.concentration_units 
_em_buffer_component.formula 
_em_buffer_component.id 
_em_buffer_component.name 
1 80 mM C8H18N2O6S2   1 PIPES                
1 1  mM C14H24N2O10   2 EGTA                 
1 1  mM MgCl2         3 'Magnesium chloride' 
1 1  mM C10H16N5O14P3 4 GTP                  
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_molwt.entity_assembly_id   1 
_em_entity_assembly_molwt.experimental_flag    YES 
_em_entity_assembly_molwt.id                   1 
_em_entity_assembly_molwt.units                MEGADALTONS 
_em_entity_assembly_molwt.value                0.4 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    cytoplasm 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   1 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                kidney 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_image_processing.details              'Gatan K3 Summit' 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               1.58 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         46 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       SUPER-RESOLUTION 
_em_image_recording.film_or_detector_model              'GATAN K3 (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     8856 
# 
_em_imaging_optics.chr_aberration_corrector   ? 
_em_imaging_optics.energyfilter_lower         ? 
_em_imaging_optics.energyfilter_slit_width    20 
_em_imaging_optics.energyfilter_name          'GIF Bioquantum' 
_em_imaging_optics.energyfilter_upper         ? 
_em_imaging_optics.id                         1 
_em_imaging_optics.imaging_id                 1 
_em_imaging_optics.phase_plate                ? 
_em_imaging_optics.sph_aberration_corrector   ? 
_em_imaging_optics.details                    ? 
# 
_em_particle_selection.details                  ? 
_em_particle_selection.id                       1 
_em_particle_selection.image_processing_id      1 
_em_particle_selection.method                   ? 
_em_particle_selection.num_particles_selected   167962 
_em_particle_selection.reference_model          ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'MODEL REFINEMENT'              ? 1  ? ? ? PHENIX 1.20.1_4487: 
'IMAGE ACQUISITION'             ? 2  1 1 1 ?      ?            
'PARTICLE SELECTION'            ? 3  1 1 1 ?      ?            
'VOLUME SELECTION'              ? 4  1 1 1 ?      ?            
CLASSIFICATION                  ? 5  1 1 1 ?      ?            
MASKING                         ? 6  1 1 1 ?      ?            
RECONSTRUCTION                  ? 7  1 1 1 ?      ?            
'INITIAL EULER ASSIGNMENT'      ? 8  1 1 1 ?      ?            
'FINAL EULER ASSIGNMENT'        ? 9  1 1 1 ?      ?            
'CTF CORRECTION'                ? 10 1 1 1 ?      ?            
'LAYERLINE INDEXING'            ? 11 1 1 1 ?      ?            
'DIFFRACTION INDEXING'          ? 12 1 1 1 ?      ?            
'MODEL FITTING'                 ? 13 1 1 1 ?      ?            
'SERIES ALIGNMENT'              ? 14 1 1 1 ?      ?            
'MOLECULAR REPLACEMENT'         ? 15 1 1 1 ?      ?            
'LATTICE DISTORTION CORRECTION' ? 16 1 1 1 ?      ?            
'SYMMETRY DETERMINATION'        ? 17 1 1 1 ?      ?            
'CRYSTALLOGRAPHY MERGING'       ? 18 1 1 1 ?      ?            
OTHER                           ? 19 1 1 1 ?      ?            
# 
_em_specimen.concentration           4.4 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   
'National Institutes of Health/National Institute of Neurological Disorders and Stroke (NIH/NINDS)' 
_pdbx_audit_support.country                'United States' 
_pdbx_audit_support.grant_number           NS003164 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   5N5N 
_pdbx_initial_refinement_model.details          ? 
# 
_pdbx_related_exp_data_set.ordinal              1 
_pdbx_related_exp_data_set.data_reference       10.1101/2023.12.01.569594 
_pdbx_related_exp_data_set.metadata_reference   ? 
_pdbx_related_exp_data_set.data_set_type        EMPIAR 
_pdbx_related_exp_data_set.details              ? 
# 
_atom_sites.entry_id                    8V2J 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C  
MG 
N  
O  
P  
S  
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1     N  N     . MET A 1 1   ? 395.494 354.149 304.975 1.00 135.57 ? 1   MET B N     1 
ATOM   2     C  CA    . MET A 1 1   ? 396.385 355.255 304.523 1.00 131.02 ? 1   MET B CA    1 
ATOM   3     C  C     . MET A 1 1   ? 396.020 356.560 305.220 1.00 131.84 ? 1   MET B C     1 
ATOM   4     O  O     . MET A 1 1   ? 394.866 356.769 305.594 1.00 131.56 ? 1   MET B O     1 
ATOM   5     C  CB    . MET A 1 1   ? 396.297 355.428 303.006 1.00 121.57 ? 1   MET B CB    1 
ATOM   6     N  N     . ARG A 1 2   ? 397.019 357.431 305.384 1.00 116.92 ? 2   ARG B N     1 
ATOM   7     C  CA    . ARG A 1 2   ? 396.855 358.747 306.005 1.00 114.24 ? 2   ARG B CA    1 
ATOM   8     C  C     . ARG A 1 2   ? 396.318 358.620 307.432 1.00 116.03 ? 2   ARG B C     1 
ATOM   9     O  O     . ARG A 1 2   ? 395.278 359.176 307.791 1.00 122.35 ? 2   ARG B O     1 
ATOM   10    C  CB    . ARG A 1 2   ? 395.949 359.646 305.156 1.00 110.28 ? 2   ARG B CB    1 
ATOM   11    C  CG    . ARG A 1 2   ? 396.518 359.980 303.786 1.00 107.65 ? 2   ARG B CG    1 
ATOM   12    C  CD    . ARG A 1 2   ? 395.651 360.990 303.051 1.00 107.59 ? 2   ARG B CD    1 
ATOM   13    N  NE    . ARG A 1 2   ? 394.290 360.507 302.844 1.00 113.05 ? 2   ARG B NE    1 
ATOM   14    C  CZ    . ARG A 1 2   ? 393.287 361.222 302.348 1.00 116.61 ? 2   ARG B CZ    1 
ATOM   15    N  NH1   . ARG A 1 2   ? 393.444 362.485 301.974 1.00 120.09 ? 2   ARG B NH1   1 
ATOM   16    N  NH2   . ARG A 1 2   ? 392.090 360.658 302.226 1.00 115.17 ? 2   ARG B NH2   1 
ATOM   17    N  N     . GLU A 1 3   ? 397.054 357.873 308.247 1.00 123.91 ? 3   GLU B N     1 
ATOM   18    C  CA    . GLU A 1 3   ? 396.646 357.622 309.618 1.00 121.37 ? 3   GLU B CA    1 
ATOM   19    C  C     . GLU A 1 3   ? 396.949 358.829 310.504 1.00 119.11 ? 3   GLU B C     1 
ATOM   20    O  O     . GLU A 1 3   ? 397.767 359.690 310.168 1.00 121.88 ? 3   GLU B O     1 
ATOM   21    C  CB    . GLU A 1 3   ? 397.352 356.383 310.168 1.00 120.50 ? 3   GLU B CB    1 
ATOM   22    C  CG    . GLU A 1 3   ? 396.786 355.053 309.680 1.00 127.73 ? 3   GLU B CG    1 
ATOM   23    C  CD    . GLU A 1 3   ? 397.192 354.718 308.256 1.00 134.14 ? 3   GLU B CD    1 
ATOM   24    O  OE1   . GLU A 1 3   ? 398.391 354.847 307.930 1.00 136.28 ? 3   GLU B OE1   1 
ATOM   25    O  OE2   . GLU A 1 3   ? 396.312 354.324 307.462 1.00 134.08 ? 3   GLU B OE2   1 
ATOM   26    N  N     . ILE A 1 4   ? 396.256 358.889 311.642 1.00 97.39  ? 4   ILE B N     1 
ATOM   27    C  CA    . ILE A 1 4   ? 396.473 359.900 312.673 1.00 95.82  ? 4   ILE B CA    1 
ATOM   28    C  C     . ILE A 1 4   ? 396.566 359.181 314.009 1.00 98.24  ? 4   ILE B C     1 
ATOM   29    O  O     . ILE A 1 4   ? 395.754 358.295 314.298 1.00 96.45  ? 4   ILE B O     1 
ATOM   30    C  CB    . ILE A 1 4   ? 395.344 360.951 312.701 1.00 93.40  ? 4   ILE B CB    1 
ATOM   31    C  CG1   . ILE A 1 4   ? 395.473 361.906 311.516 1.00 98.25  ? 4   ILE B CG1   1 
ATOM   32    C  CG2   . ILE A 1 4   ? 395.372 361.773 314.003 1.00 92.54  ? 4   ILE B CG2   1 
ATOM   33    C  CD1   . ILE A 1 4   ? 394.164 362.538 311.096 1.00 104.76 ? 4   ILE B CD1   1 
ATOM   34    N  N     . VAL A 1 5   ? 397.546 359.570 314.821 1.00 109.30 ? 5   VAL B N     1 
ATOM   35    C  CA    . VAL A 1 5   ? 397.734 359.054 316.173 1.00 107.64 ? 5   VAL B CA    1 
ATOM   36    C  C     . VAL A 1 5   ? 397.305 360.156 317.130 1.00 109.11 ? 5   VAL B C     1 
ATOM   37    O  O     . VAL A 1 5   ? 397.885 361.248 317.127 1.00 112.98 ? 5   VAL B O     1 
ATOM   38    C  CB    . VAL A 1 5   ? 399.191 358.628 316.415 1.00 112.09 ? 5   VAL B CB    1 
ATOM   39    C  CG1   . VAL A 1 5   ? 399.527 358.545 317.912 1.00 112.52 ? 5   VAL B CG1   1 
ATOM   40    C  CG2   . VAL A 1 5   ? 399.462 357.298 315.734 1.00 113.83 ? 5   VAL B CG2   1 
ATOM   41    N  N     . HIS A 1 6   ? 396.298 359.867 317.950 1.00 97.79  ? 6   HIS B N     1 
ATOM   42    C  CA    . HIS A 1 6   ? 395.738 360.822 318.897 1.00 93.80  ? 6   HIS B CA    1 
ATOM   43    C  C     . HIS A 1 6   ? 396.289 360.551 320.288 1.00 88.54  ? 6   HIS B C     1 
ATOM   44    O  O     . HIS A 1 6   ? 396.372 359.398 320.718 1.00 97.27  ? 6   HIS B O     1 
ATOM   45    C  CB    . HIS A 1 6   ? 394.209 360.735 318.918 1.00 95.14  ? 6   HIS B CB    1 
ATOM   46    C  CG    . HIS A 1 6   ? 393.578 361.425 320.090 1.00 99.82  ? 6   HIS B CG    1 
ATOM   47    N  ND1   . HIS A 1 6   ? 393.348 362.788 320.124 1.00 99.93  ? 6   HIS B ND1   1 
ATOM   48    C  CD2   . HIS A 1 6   ? 393.127 360.937 321.268 1.00 99.07  ? 6   HIS B CD2   1 
ATOM   49    C  CE1   . HIS A 1 6   ? 392.780 363.106 321.273 1.00 101.32 ? 6   HIS B CE1   1 
ATOM   50    N  NE2   . HIS A 1 6   ? 392.640 362.001 321.986 1.00 97.62  ? 6   HIS B NE2   1 
ATOM   51    N  N     . ILE A 1 7   ? 396.671 361.624 320.980 1.00 91.04  ? 7   ILE B N     1 
ATOM   52    C  CA    . ILE A 1 7   ? 397.109 361.585 322.370 1.00 95.39  ? 7   ILE B CA    1 
ATOM   53    C  C     . ILE A 1 7   ? 396.218 362.535 323.158 1.00 97.77  ? 7   ILE B C     1 
ATOM   54    O  O     . ILE A 1 7   ? 395.744 363.544 322.628 1.00 107.62 ? 7   ILE B O     1 
ATOM   55    C  CB    . ILE A 1 7   ? 398.605 361.966 322.507 1.00 92.45  ? 7   ILE B CB    1 
ATOM   56    C  CG1   . ILE A 1 7   ? 399.463 361.065 321.610 1.00 94.57  ? 7   ILE B CG1   1 
ATOM   57    C  CG2   . ILE A 1 7   ? 399.080 361.884 323.969 1.00 96.22  ? 7   ILE B CG2   1 
ATOM   58    C  CD1   . ILE A 1 7   ? 399.926 361.743 320.342 1.00 97.69  ? 7   ILE B CD1   1 
ATOM   59    N  N     . GLN A 1 8   ? 395.968 362.192 324.423 1.00 94.85  ? 8   GLN B N     1 
ATOM   60    C  CA    . GLN A 1 8   ? 395.201 363.041 325.332 1.00 97.64  ? 8   GLN B CA    1 
ATOM   61    C  C     . GLN A 1 8   ? 395.908 363.049 326.677 1.00 101.71 ? 8   GLN B C     1 
ATOM   62    O  O     . GLN A 1 8   ? 396.119 361.991 327.276 1.00 110.64 ? 8   GLN B O     1 
ATOM   63    C  CB    . GLN A 1 8   ? 393.746 362.566 325.477 1.00 104.07 ? 8   GLN B CB    1 
ATOM   64    C  CG    . GLN A 1 8   ? 393.556 361.127 325.926 1.00 106.33 ? 8   GLN B CG    1 
ATOM   65    C  CD    . GLN A 1 8   ? 392.156 360.612 325.667 1.00 105.43 ? 8   GLN B CD    1 
ATOM   66    O  OE1   . GLN A 1 8   ? 391.299 360.626 326.548 1.00 109.72 ? 8   GLN B OE1   1 
ATOM   67    N  NE2   . GLN A 1 8   ? 391.922 360.134 324.454 1.00 103.26 ? 8   GLN B NE2   1 
ATOM   68    N  N     . ALA A 1 9   ? 396.283 364.244 327.131 1.00 91.19  ? 9   ALA B N     1 
ATOM   69    C  CA    . ALA A 1 9   ? 397.001 364.452 328.380 1.00 86.95  ? 9   ALA B CA    1 
ATOM   70    C  C     . ALA A 1 9   ? 396.264 365.489 329.213 1.00 90.80  ? 9   ALA B C     1 
ATOM   71    O  O     . ALA A 1 9   ? 395.696 366.442 328.672 1.00 98.06  ? 9   ALA B O     1 
ATOM   72    C  CB    . ALA A 1 9   ? 398.436 364.912 328.119 1.00 88.33  ? 9   ALA B CB    1 
ATOM   73    N  N     . GLY A 1 10  ? 396.281 365.299 330.528 1.00 103.90 ? 10  GLY B N     1 
ATOM   74    C  CA    . GLY A 1 10  ? 395.544 366.151 331.435 1.00 108.09 ? 10  GLY B CA    1 
ATOM   75    C  C     . GLY A 1 10  ? 394.107 365.695 331.595 1.00 108.37 ? 10  GLY B C     1 
ATOM   76    O  O     . GLY A 1 10  ? 393.569 364.925 330.802 1.00 113.53 ? 10  GLY B O     1 
ATOM   77    N  N     . GLN A 1 11  ? 393.475 366.182 332.664 1.00 107.77 ? 11  GLN B N     1 
ATOM   78    C  CA    . GLN A 1 11  ? 392.046 365.945 332.849 1.00 107.66 ? 11  GLN B CA    1 
ATOM   79    C  C     . GLN A 1 11  ? 391.251 366.566 331.710 1.00 114.51 ? 11  GLN B C     1 
ATOM   80    O  O     . GLN A 1 11  ? 390.330 365.945 331.161 1.00 123.63 ? 11  GLN B O     1 
ATOM   81    C  CB    . GLN A 1 11  ? 391.594 366.516 334.195 1.00 110.21 ? 11  GLN B CB    1 
ATOM   82    C  CG    . GLN A 1 11  ? 390.109 366.345 334.499 1.00 115.92 ? 11  GLN B CG    1 
ATOM   83    C  CD    . GLN A 1 11  ? 389.766 366.728 335.922 1.00 121.01 ? 11  GLN B CD    1 
ATOM   84    O  OE1   . GLN A 1 11  ? 390.580 367.319 336.630 1.00 116.46 ? 11  GLN B OE1   1 
ATOM   85    N  NE2   . GLN A 1 11  ? 388.551 366.401 336.347 1.00 123.10 ? 11  GLN B NE2   1 
ATOM   86    N  N     . CYS A 1 12  ? 391.606 367.798 331.342 1.00 111.55 ? 12  CYS B N     1 
ATOM   87    C  CA    . CYS A 1 12  ? 390.924 368.495 330.260 1.00 113.59 ? 12  CYS B CA    1 
ATOM   88    C  C     . CYS A 1 12  ? 391.092 367.755 328.941 1.00 113.43 ? 12  CYS B C     1 
ATOM   89    O  O     . CYS A 1 12  ? 390.120 367.532 328.206 1.00 118.02 ? 12  CYS B O     1 
ATOM   90    C  CB    . CYS A 1 12  ? 391.477 369.912 330.150 1.00 112.12 ? 12  CYS B CB    1 
ATOM   91    S  SG    . CYS A 1 12  ? 390.986 370.784 328.672 1.00 123.26 ? 12  CYS B SG    1 
ATOM   92    N  N     . GLY A 1 13  ? 392.328 367.358 328.634 1.00 109.97 ? 13  GLY B N     1 
ATOM   93    C  CA    . GLY A 1 13  ? 392.576 366.628 327.406 1.00 111.96 ? 13  GLY B CA    1 
ATOM   94    C  C     . GLY A 1 13  ? 391.876 365.286 327.382 1.00 110.17 ? 13  GLY B C     1 
ATOM   95    O  O     . GLY A 1 13  ? 391.338 364.880 326.353 1.00 118.86 ? 13  GLY B O     1 
ATOM   96    N  N     . ASN A 1 14  ? 391.855 364.591 328.520 1.00 108.81 ? 14  ASN B N     1 
ATOM   97    C  CA    . ASN A 1 14  ? 391.195 363.292 328.580 1.00 109.74 ? 14  ASN B CA    1 
ATOM   98    C  C     . ASN A 1 14  ? 389.693 363.422 328.360 1.00 112.78 ? 14  ASN B C     1 
ATOM   99    O  O     . ASN A 1 14  ? 389.098 362.635 327.615 1.00 119.68 ? 14  ASN B O     1 
ATOM   100   C  CB    . ASN A 1 14  ? 391.484 362.615 329.918 1.00 111.01 ? 14  ASN B CB    1 
ATOM   101   C  CG    . ASN A 1 14  ? 392.767 361.815 329.896 1.00 112.97 ? 14  ASN B CG    1 
ATOM   102   O  OD1   . ASN A 1 14  ? 392.745 360.588 329.827 1.00 111.67 ? 14  ASN B OD1   1 
ATOM   103   N  ND2   . ASN A 1 14  ? 393.896 362.507 329.944 1.00 118.27 ? 14  ASN B ND2   1 
ATOM   104   N  N     . GLN A 1 15  ? 389.064 364.419 328.984 1.00 102.30 ? 15  GLN B N     1 
ATOM   105   C  CA    . GLN A 1 15  ? 387.622 364.581 328.819 1.00 99.92  ? 15  GLN B CA    1 
ATOM   106   C  C     . GLN A 1 15  ? 387.269 365.011 327.399 1.00 102.40 ? 15  GLN B C     1 
ATOM   107   O  O     . GLN A 1 15  ? 386.296 364.508 326.813 1.00 106.56 ? 15  GLN B O     1 
ATOM   108   C  CB    . GLN A 1 15  ? 387.098 365.582 329.845 1.00 96.82  ? 15  GLN B CB    1 
ATOM   109   C  CG    . GLN A 1 15  ? 387.088 365.025 331.259 1.00 101.43 ? 15  GLN B CG    1 
ATOM   110   C  CD    . GLN A 1 15  ? 386.664 366.046 332.293 1.00 113.02 ? 15  GLN B CD    1 
ATOM   111   O  OE1   . GLN A 1 15  ? 387.110 367.192 332.269 1.00 114.83 ? 15  GLN B OE1   1 
ATOM   112   N  NE2   . GLN A 1 15  ? 385.797 365.634 333.210 1.00 114.38 ? 15  GLN B NE2   1 
ATOM   113   N  N     . ILE A 1 16  ? 388.052 365.928 326.822 1.00 83.96  ? 16  ILE B N     1 
ATOM   114   C  CA    . ILE A 1 16  ? 387.788 366.342 325.448 1.00 76.56  ? 16  ILE B CA    1 
ATOM   115   C  C     . ILE A 1 16  ? 388.023 365.180 324.493 1.00 87.05  ? 16  ILE B C     1 
ATOM   116   O  O     . ILE A 1 16  ? 387.297 365.022 323.509 1.00 94.64  ? 16  ILE B O     1 
ATOM   117   C  CB    . ILE A 1 16  ? 388.634 367.575 325.074 1.00 77.43  ? 16  ILE B CB    1 
ATOM   118   C  CG1   . ILE A 1 16  ? 388.120 368.815 325.812 1.00 87.99  ? 16  ILE B CG1   1 
ATOM   119   C  CG2   . ILE A 1 16  ? 388.592 367.836 323.563 1.00 88.81  ? 16  ILE B CG2   1 
ATOM   120   C  CD1   . ILE A 1 16  ? 389.134 369.929 325.938 1.00 93.08  ? 16  ILE B CD1   1 
ATOM   121   N  N     . GLY A 1 17  ? 389.026 364.344 324.766 1.00 101.75 ? 17  GLY B N     1 
ATOM   122   C  CA    . GLY A 1 17  ? 389.246 363.178 323.929 1.00 104.53 ? 17  GLY B CA    1 
ATOM   123   C  C     . GLY A 1 17  ? 388.120 362.170 324.033 1.00 106.47 ? 17  GLY B C     1 
ATOM   124   O  O     . GLY A 1 17  ? 387.750 361.537 323.041 1.00 110.34 ? 17  GLY B O     1 
ATOM   125   N  N     . ALA A 1 18  ? 387.562 362.003 325.235 1.00 98.11  ? 18  ALA B N     1 
ATOM   126   C  CA    . ALA A 1 18  ? 386.426 361.104 325.407 1.00 101.13 ? 18  ALA B CA    1 
ATOM   127   C  C     . ALA A 1 18  ? 385.226 361.583 324.600 1.00 101.76 ? 18  ALA B C     1 
ATOM   128   O  O     . ALA A 1 18  ? 384.592 360.799 323.882 1.00 102.77 ? 18  ALA B O     1 
ATOM   129   C  CB    . ALA A 1 18  ? 386.067 360.992 326.888 1.00 96.22  ? 18  ALA B CB    1 
ATOM   130   N  N     . LYS A 1 19  ? 384.914 362.879 324.685 1.00 100.38 ? 19  LYS B N     1 
ATOM   131   C  CA    . LYS A 1 19  ? 383.798 363.397 323.896 1.00 100.59 ? 19  LYS B CA    1 
ATOM   132   C  C     . LYS A 1 19  ? 384.099 363.351 322.401 1.00 103.39 ? 19  LYS B C     1 
ATOM   133   O  O     . LYS A 1 19  ? 383.197 363.094 321.592 1.00 106.24 ? 19  LYS B O     1 
ATOM   134   C  CB    . LYS A 1 19  ? 383.460 364.821 324.328 1.00 101.39 ? 19  LYS B CB    1 
ATOM   135   C  CG    . LYS A 1 19  ? 382.059 365.294 323.865 1.00 104.90 ? 19  LYS B CG    1 
ATOM   136   C  CD    . LYS A 1 19  ? 380.847 364.779 324.679 1.00 102.19 ? 19  LYS B CD    1 
ATOM   137   C  CE    . LYS A 1 19  ? 381.004 364.822 326.195 1.00 106.34 ? 19  LYS B CE    1 
ATOM   138   N  NZ    . LYS A 1 19  ? 379.691 364.747 326.889 1.00 111.00 ? 19  LYS B NZ    1 
ATOM   139   N  N     . PHE A 1 20  ? 385.356 363.591 322.021 1.00 94.46  ? 20  PHE B N     1 
ATOM   140   C  CA    . PHE A 1 20  ? 385.758 363.518 320.621 1.00 90.05  ? 20  PHE B CA    1 
ATOM   141   C  C     . PHE A 1 20  ? 385.558 362.117 320.065 1.00 97.16  ? 20  PHE B C     1 
ATOM   142   O  O     . PHE A 1 20  ? 385.011 361.949 318.970 1.00 103.34 ? 20  PHE B O     1 
ATOM   143   C  CB    . PHE A 1 20  ? 387.218 363.961 320.499 1.00 97.21  ? 20  PHE B CB    1 
ATOM   144   C  CG    . PHE A 1 20  ? 387.913 363.478 319.260 1.00 103.16 ? 20  PHE B CG    1 
ATOM   145   C  CD1   . PHE A 1 20  ? 387.649 364.048 318.029 1.00 103.23 ? 20  PHE B CD1   1 
ATOM   146   C  CD2   . PHE A 1 20  ? 388.859 362.470 319.337 1.00 99.82  ? 20  PHE B CD2   1 
ATOM   147   C  CE1   . PHE A 1 20  ? 388.302 363.608 316.895 1.00 94.35  ? 20  PHE B CE1   1 
ATOM   148   C  CE2   . PHE A 1 20  ? 389.514 362.027 318.208 1.00 97.02  ? 20  PHE B CE2   1 
ATOM   149   C  CZ    . PHE A 1 20  ? 389.236 362.596 316.986 1.00 95.17  ? 20  PHE B CZ    1 
ATOM   150   N  N     . TRP A 1 21  ? 385.962 361.096 320.820 1.00 89.34  ? 21  TRP B N     1 
ATOM   151   C  CA    . TRP A 1 21  ? 385.775 359.731 320.347 1.00 92.00  ? 21  TRP B CA    1 
ATOM   152   C  C     . TRP A 1 21  ? 384.309 359.333 320.363 1.00 92.59  ? 21  TRP B C     1 
ATOM   153   O  O     . TRP A 1 21  ? 383.881 358.547 319.511 1.00 96.75  ? 21  TRP B O     1 
ATOM   154   C  CB    . TRP A 1 21  ? 386.608 358.760 321.180 1.00 85.93  ? 21  TRP B CB    1 
ATOM   155   C  CG    . TRP A 1 21  ? 388.048 358.770 320.797 1.00 81.13  ? 21  TRP B CG    1 
ATOM   156   C  CD1   . TRP A 1 21  ? 389.096 359.168 321.567 1.00 82.86  ? 21  TRP B CD1   1 
ATOM   157   C  CD2   . TRP A 1 21  ? 388.601 358.381 319.535 1.00 80.64  ? 21  TRP B CD2   1 
ATOM   158   N  NE1   . TRP A 1 21  ? 390.270 359.043 320.867 1.00 88.94  ? 21  TRP B NE1   1 
ATOM   159   C  CE2   . TRP A 1 21  ? 389.992 358.564 319.615 1.00 86.52  ? 21  TRP B CE2   1 
ATOM   160   C  CE3   . TRP A 1 21  ? 388.053 357.895 318.345 1.00 90.43  ? 21  TRP B CE3   1 
ATOM   161   C  CZ2   . TRP A 1 21  ? 390.844 358.276 318.553 1.00 89.37  ? 21  TRP B CZ2   1 
ATOM   162   C  CZ3   . TRP A 1 21  ? 388.898 357.611 317.293 1.00 101.14 ? 21  TRP B CZ3   1 
ATOM   163   C  CH2   . TRP A 1 21  ? 390.280 357.799 317.406 1.00 96.35  ? 21  TRP B CH2   1 
ATOM   164   N  N     . GLU A 1 22  ? 383.524 359.871 321.301 1.00 98.65  ? 22  GLU B N     1 
ATOM   165   C  CA    . GLU A 1 22  ? 382.084 359.640 321.274 1.00 98.10  ? 22  GLU B CA    1 
ATOM   166   C  C     . GLU A 1 22  ? 381.476 360.178 319.984 1.00 100.50 ? 22  GLU B C     1 
ATOM   167   O  O     . GLU A 1 22  ? 380.702 359.485 319.314 1.00 107.34 ? 22  GLU B O     1 
ATOM   168   C  CB    . GLU A 1 22  ? 381.430 360.284 322.499 1.00 101.80 ? 22  GLU B CB    1 
ATOM   169   C  CG    . GLU A 1 22  ? 379.897 360.242 322.515 1.00 104.60 ? 22  GLU B CG    1 
ATOM   170   C  CD    . GLU A 1 22  ? 379.301 360.643 323.855 1.00 113.43 ? 22  GLU B CD    1 
ATOM   171   O  OE1   . GLU A 1 22  ? 379.967 360.465 324.897 1.00 111.54 ? 22  GLU B OE1   1 
ATOM   172   O  OE2   . GLU A 1 22  ? 378.157 361.142 323.864 1.00 120.16 ? 22  GLU B OE2   1 
ATOM   173   N  N     . VAL A 1 23  ? 381.848 361.402 319.602 1.00 89.68  ? 23  VAL B N     1 
ATOM   174   C  CA    . VAL A 1 23  ? 381.314 361.996 318.376 1.00 92.34  ? 23  VAL B CA    1 
ATOM   175   C  C     . VAL A 1 23  ? 381.787 361.221 317.150 1.00 96.31  ? 23  VAL B C     1 
ATOM   176   O  O     . VAL A 1 23  ? 381.013 360.989 316.208 1.00 99.94  ? 23  VAL B O     1 
ATOM   177   C  CB    . VAL A 1 23  ? 381.701 363.486 318.293 1.00 88.73  ? 23  VAL B CB    1 
ATOM   178   C  CG1   . VAL A 1 23  ? 381.363 364.066 316.917 1.00 92.93  ? 23  VAL B CG1   1 
ATOM   179   C  CG2   . VAL A 1 23  ? 380.991 364.283 319.381 1.00 94.50  ? 23  VAL B CG2   1 
ATOM   180   N  N     . ILE A 1 24  ? 383.061 360.821 317.135 1.00 86.48  ? 24  ILE B N     1 
ATOM   181   C  CA    . ILE A 1 24  ? 383.615 360.119 315.978 1.00 86.88  ? 24  ILE B CA    1 
ATOM   182   C  C     . ILE A 1 24  ? 382.921 358.776 315.795 1.00 92.99  ? 24  ILE B C     1 
ATOM   183   O  O     . ILE A 1 24  ? 382.492 358.426 314.689 1.00 100.67 ? 24  ILE B O     1 
ATOM   184   C  CB    . ILE A 1 24  ? 385.141 359.956 316.132 1.00 86.05  ? 24  ILE B CB    1 
ATOM   185   C  CG1   . ILE A 1 24  ? 385.853 361.310 315.997 1.00 86.20  ? 24  ILE B CG1   1 
ATOM   186   C  CG2   . ILE A 1 24  ? 385.711 358.961 315.112 1.00 93.11  ? 24  ILE B CG2   1 
ATOM   187   C  CD1   . ILE A 1 24  ? 386.025 361.814 314.570 1.00 92.79  ? 24  ILE B CD1   1 
ATOM   188   N  N     . SER A 1 25  ? 382.788 358.009 316.879 1.00 89.53  ? 25  SER B N     1 
ATOM   189   C  CA    . SER A 1 25  ? 382.107 356.724 316.790 1.00 95.36  ? 25  SER B CA    1 
ATOM   190   C  C     . SER A 1 25  ? 380.632 356.897 316.465 1.00 98.70  ? 25  SER B C     1 
ATOM   191   O  O     . SER A 1 25  ? 380.051 356.049 315.779 1.00 101.60 ? 25  SER B O     1 
ATOM   192   C  CB    . SER A 1 25  ? 382.276 355.949 318.096 1.00 97.16  ? 25  SER B CB    1 
ATOM   193   O  OG    . SER A 1 25  ? 381.762 356.674 319.200 1.00 104.12 ? 25  SER B OG    1 
ATOM   194   N  N     . ASP A 1 26  ? 380.011 357.982 316.935 1.00 108.10 ? 26  ASP B N     1 
ATOM   195   C  CA    . ASP A 1 26  ? 378.608 358.220 316.625 1.00 107.06 ? 26  ASP B CA    1 
ATOM   196   C  C     . ASP A 1 26  ? 378.408 358.452 315.134 1.00 101.72 ? 26  ASP B C     1 
ATOM   197   O  O     . ASP A 1 26  ? 377.530 357.838 314.516 1.00 109.10 ? 26  ASP B O     1 
ATOM   198   C  CB    . ASP A 1 26  ? 378.093 359.413 317.428 1.00 113.70 ? 26  ASP B CB    1 
ATOM   199   C  CG    . ASP A 1 26  ? 376.677 359.797 317.057 1.00 113.49 ? 26  ASP B CG    1 
ATOM   200   O  OD1   . ASP A 1 26  ? 375.875 358.891 316.744 1.00 110.52 ? 26  ASP B OD1   1 
ATOM   201   O  OD2   . ASP A 1 26  ? 376.364 361.005 317.076 1.00 113.07 ? 26  ASP B OD2   1 
ATOM   202   N  N     . GLU A 1 27  ? 379.223 359.321 314.532 1.00 95.43  ? 27  GLU B N     1 
ATOM   203   C  CA    . GLU A 1 27  ? 379.046 359.621 313.115 1.00 107.26 ? 27  GLU B CA    1 
ATOM   204   C  C     . GLU A 1 27  ? 379.648 358.561 312.198 1.00 106.60 ? 27  GLU B C     1 
ATOM   205   O  O     . GLU A 1 27  ? 379.342 358.573 311.000 1.00 112.66 ? 27  GLU B O     1 
ATOM   206   C  CB    . GLU A 1 27  ? 379.621 361.002 312.782 1.00 107.56 ? 27  GLU B CB    1 
ATOM   207   C  CG    . GLU A 1 27  ? 381.127 361.077 312.580 1.00 105.29 ? 27  GLU B CG    1 
ATOM   208   C  CD    . GLU A 1 27  ? 381.640 362.505 312.600 1.00 112.63 ? 27  GLU B CD    1 
ATOM   209   O  OE1   . GLU A 1 27  ? 381.212 363.295 313.468 1.00 110.86 ? 27  GLU B OE1   1 
ATOM   210   O  OE2   . GLU A 1 27  ? 382.471 362.847 311.735 1.00 115.43 ? 27  GLU B OE2   1 
ATOM   211   N  N     . HIS A 1 28  ? 380.487 357.658 312.716 1.00 104.20 ? 28  HIS B N     1 
ATOM   212   C  CA    . HIS A 1 28  ? 380.900 356.463 311.984 1.00 105.36 ? 28  HIS B CA    1 
ATOM   213   C  C     . HIS A 1 28  ? 380.015 355.251 312.259 1.00 109.58 ? 28  HIS B C     1 
ATOM   214   O  O     . HIS A 1 28  ? 380.221 354.205 311.635 1.00 111.78 ? 28  HIS B O     1 
ATOM   215   C  CB    . HIS A 1 28  ? 382.354 356.116 312.320 1.00 108.41 ? 28  HIS B CB    1 
ATOM   216   C  CG    . HIS A 1 28  ? 383.353 356.825 311.460 1.00 112.58 ? 28  HIS B CG    1 
ATOM   217   N  ND1   . HIS A 1 28  ? 383.597 356.465 310.153 1.00 113.04 ? 28  HIS B ND1   1 
ATOM   218   C  CD2   . HIS A 1 28  ? 384.160 357.881 311.715 1.00 113.88 ? 28  HIS B CD2   1 
ATOM   219   C  CE1   . HIS A 1 28  ? 384.519 357.262 309.643 1.00 108.37 ? 28  HIS B CE1   1 
ATOM   220   N  NE2   . HIS A 1 28  ? 384.876 358.131 310.571 1.00 108.68 ? 28  HIS B NE2   1 
ATOM   221   N  N     . GLY A 1 29  ? 379.040 355.358 313.156 1.00 114.35 ? 29  GLY B N     1 
ATOM   222   C  CA    . GLY A 1 29  ? 378.131 354.254 313.406 1.00 115.19 ? 29  GLY B CA    1 
ATOM   223   C  C     . GLY A 1 29  ? 378.772 353.060 314.079 1.00 114.80 ? 29  GLY B C     1 
ATOM   224   O  O     . GLY A 1 29  ? 378.463 351.916 313.720 1.00 116.80 ? 29  GLY B O     1 
ATOM   225   N  N     . ILE A 1 30  ? 379.652 353.301 315.051 1.00 106.39 ? 30  ILE B N     1 
ATOM   226   C  CA    . ILE A 1 30  ? 380.298 352.257 315.842 1.00 102.00 ? 30  ILE B CA    1 
ATOM   227   C  C     . ILE A 1 30  ? 379.721 352.314 317.248 1.00 104.78 ? 30  ILE B C     1 
ATOM   228   O  O     . ILE A 1 30  ? 379.685 353.382 317.871 1.00 103.85 ? 30  ILE B O     1 
ATOM   229   C  CB    . ILE A 1 30  ? 381.828 352.424 315.855 1.00 90.77  ? 30  ILE B CB    1 
ATOM   230   C  CG1   . ILE A 1 30  ? 382.408 351.996 314.508 1.00 95.54  ? 30  ILE B CG1   1 
ATOM   231   C  CG2   . ILE A 1 30  ? 382.478 351.591 316.966 1.00 96.50  ? 30  ILE B CG2   1 
ATOM   232   C  CD1   . ILE A 1 30  ? 383.714 352.661 314.164 1.00 95.69  ? 30  ILE B CD1   1 
ATOM   233   N  N     . ASP A 1 31  ? 379.278 351.164 317.748 1.00 113.12 ? 31  ASP B N     1 
ATOM   234   C  CA    . ASP A 1 31  ? 378.726 351.072 319.083 1.00 107.77 ? 31  ASP B CA    1 
ATOM   235   C  C     . ASP A 1 31  ? 379.850 351.239 320.103 1.00 104.25 ? 31  ASP B C     1 
ATOM   236   O  O     . ASP A 1 31  ? 381.029 351.179 319.748 1.00 108.35 ? 31  ASP B O     1 
ATOM   237   C  CB    . ASP A 1 31  ? 378.016 349.732 319.266 1.00 107.06 ? 31  ASP B CB    1 
ATOM   238   C  CG    . ASP A 1 31  ? 376.762 349.619 318.425 1.00 113.41 ? 31  ASP B CG    1 
ATOM   239   O  OD1   . ASP A 1 31  ? 376.548 350.489 317.556 1.00 111.94 ? 31  ASP B OD1   1 
ATOM   240   O  OD2   . ASP A 1 31  ? 375.990 348.658 318.631 1.00 108.43 ? 31  ASP B OD2   1 
ATOM   241   N  N     . PRO A 1 32  ? 379.521 351.479 321.380 1.00 102.30 ? 32  PRO B N     1 
ATOM   242   C  CA    . PRO A 1 32  ? 380.587 351.540 322.398 1.00 107.44 ? 32  PRO B CA    1 
ATOM   243   C  C     . PRO A 1 32  ? 381.378 350.250 322.531 1.00 105.28 ? 32  PRO B C     1 
ATOM   244   O  O     . PRO A 1 32  ? 382.548 350.289 322.930 1.00 99.73  ? 32  PRO B O     1 
ATOM   245   C  CB    . PRO A 1 32  ? 379.824 351.866 323.690 1.00 107.61 ? 32  PRO B CB    1 
ATOM   246   C  CG    . PRO A 1 32  ? 378.547 352.464 323.245 1.00 105.06 ? 32  PRO B CG    1 
ATOM   247   C  CD    . PRO A 1 32  ? 378.203 351.781 321.966 1.00 100.40 ? 32  PRO B CD    1 
ATOM   248   N  N     . THR A 1 33  ? 380.775 349.106 322.206 1.00 107.94 ? 33  THR B N     1 
ATOM   249   C  CA    . THR A 1 33  ? 381.498 347.841 322.195 1.00 103.98 ? 33  THR B CA    1 
ATOM   250   C  C     . THR A 1 33  ? 382.545 347.759 321.089 1.00 103.64 ? 33  THR B C     1 
ATOM   251   O  O     . THR A 1 33  ? 383.411 346.881 321.154 1.00 108.64 ? 33  THR B O     1 
ATOM   252   C  CB    . THR A 1 33  ? 380.517 346.677 322.042 1.00 106.48 ? 33  THR B CB    1 
ATOM   253   O  OG1   . THR A 1 33  ? 379.753 346.847 320.842 1.00 103.59 ? 33  THR B OG1   1 
ATOM   254   C  CG2   . THR A 1 33  ? 379.576 346.610 323.236 1.00 104.41 ? 33  THR B CG2   1 
ATOM   255   N  N     . GLY A 1 34  ? 382.489 348.639 320.084 1.00 99.66  ? 34  GLY B N     1 
ATOM   256   C  CA    . GLY A 1 34  ? 383.417 348.638 318.972 1.00 100.73 ? 34  GLY B CA    1 
ATOM   257   C  C     . GLY A 1 34  ? 382.929 347.925 317.731 1.00 97.80  ? 34  GLY B C     1 
ATOM   258   O  O     . GLY A 1 34  ? 383.623 347.961 316.709 1.00 94.29  ? 34  GLY B O     1 
ATOM   259   N  N     . THR A 1 35  ? 381.773 347.270 317.787 1.00 100.76 ? 35  THR B N     1 
ATOM   260   C  CA    . THR A 1 35  ? 381.209 346.628 316.613 1.00 102.77 ? 35  THR B CA    1 
ATOM   261   C  C     . THR A 1 35  ? 380.477 347.663 315.765 1.00 106.73 ? 35  THR B C     1 
ATOM   262   O  O     . THR A 1 35  ? 379.702 348.471 316.286 1.00 112.22 ? 35  THR B O     1 
ATOM   263   C  CB    . THR A 1 35  ? 380.265 345.509 317.037 1.00 105.42 ? 35  THR B CB    1 
ATOM   264   O  OG1   . THR A 1 35  ? 380.885 344.743 318.073 1.00 101.99 ? 35  THR B OG1   1 
ATOM   265   C  CG2   . THR A 1 35  ? 379.967 344.574 315.868 1.00 102.77 ? 35  THR B CG2   1 
ATOM   266   N  N     . TYR A 1 36  ? 380.731 347.633 314.459 1.00 106.34 ? 36  TYR B N     1 
ATOM   267   C  CA    . TYR A 1 36  ? 380.122 348.580 313.532 1.00 105.11 ? 36  TYR B CA    1 
ATOM   268   C  C     . TYR A 1 36  ? 378.680 348.198 313.229 1.00 108.69 ? 36  TYR B C     1 
ATOM   269   O  O     . TYR A 1 36  ? 378.407 347.088 312.763 1.00 108.54 ? 36  TYR B O     1 
ATOM   270   C  CB    . TYR A 1 36  ? 380.931 348.615 312.240 1.00 102.77 ? 36  TYR B CB    1 
ATOM   271   C  CG    . TYR A 1 36  ? 380.318 349.421 311.120 1.00 104.18 ? 36  TYR B CG    1 
ATOM   272   C  CD1   . TYR A 1 36  ? 380.430 350.800 311.084 1.00 109.37 ? 36  TYR B CD1   1 
ATOM   273   C  CD2   . TYR A 1 36  ? 379.652 348.790 310.075 1.00 103.81 ? 36  TYR B CD2   1 
ATOM   274   C  CE1   . TYR A 1 36  ? 379.887 351.530 310.048 1.00 112.21 ? 36  TYR B CE1   1 
ATOM   275   C  CE2   . TYR A 1 36  ? 379.104 349.513 309.041 1.00 106.12 ? 36  TYR B CE2   1 
ATOM   276   C  CZ    . TYR A 1 36  ? 379.222 350.881 309.030 1.00 109.78 ? 36  TYR B CZ    1 
ATOM   277   O  OH    . TYR A 1 36  ? 378.676 351.606 307.998 1.00 114.33 ? 36  TYR B OH    1 
ATOM   278   N  N     . HIS A 1 37  ? 377.757 349.143 313.482 1.00 119.65 ? 37  HIS B N     1 
ATOM   279   C  CA    . HIS A 1 37  ? 376.357 349.035 313.081 1.00 116.87 ? 37  HIS B CA    1 
ATOM   280   C  C     . HIS A 1 37  ? 375.940 350.223 312.210 1.00 118.41 ? 37  HIS B C     1 
ATOM   281   O  O     . HIS A 1 37  ? 374.738 350.472 312.053 1.00 117.61 ? 37  HIS B O     1 
ATOM   282   C  CB    . HIS A 1 37  ? 375.346 348.977 314.268 1.00 114.71 ? 37  HIS B CB    1 
ATOM   283   C  CG    . HIS A 1 37  ? 375.496 347.818 315.218 1.00 118.99 ? 37  HIS B CG    1 
ATOM   284   N  ND1   . HIS A 1 37  ? 376.698 347.251 315.588 1.00 119.45 ? 37  HIS B ND1   1 
ATOM   285   C  CD2   . HIS A 1 37  ? 374.539 347.081 315.832 1.00 123.21 ? 37  HIS B CD2   1 
ATOM   286   C  CE1   . HIS A 1 37  ? 376.475 346.249 316.418 1.00 119.54 ? 37  HIS B CE1   1 
ATOM   287   N  NE2   . HIS A 1 37  ? 375.173 346.121 316.576 1.00 122.81 ? 37  HIS B NE2   1 
ATOM   288   N  N     . GLY A 1 38  ? 376.888 350.954 311.624 1.00 124.09 ? 38  GLY B N     1 
ATOM   289   C  CA    . GLY A 1 38  ? 376.528 352.065 310.770 1.00 121.52 ? 38  GLY B CA    1 
ATOM   290   C  C     . GLY A 1 38  ? 375.943 351.604 309.451 1.00 122.44 ? 38  GLY B C     1 
ATOM   291   O  O     . GLY A 1 38  ? 376.047 350.441 309.062 1.00 123.57 ? 38  GLY B O     1 
ATOM   292   N  N     . ASP A 1 39  ? 375.331 352.557 308.747 1.00 136.63 ? 39  ASP B N     1 
ATOM   293   C  CA    . ASP A 1 39  ? 374.612 352.276 307.506 1.00 137.37 ? 39  ASP B CA    1 
ATOM   294   C  C     . ASP A 1 39  ? 375.424 352.575 306.252 1.00 138.62 ? 39  ASP B C     1 
ATOM   295   O  O     . ASP A 1 39  ? 375.276 351.861 305.254 1.00 136.26 ? 39  ASP B O     1 
ATOM   296   C  CB    . ASP A 1 39  ? 373.293 353.068 307.449 1.00 137.70 ? 39  ASP B CB    1 
ATOM   297   C  CG    . ASP A 1 39  ? 373.487 354.572 307.596 1.00 140.83 ? 39  ASP B CG    1 
ATOM   298   O  OD1   . ASP A 1 39  ? 374.637 355.024 307.777 1.00 141.29 ? 39  ASP B OD1   1 
ATOM   299   O  OD2   . ASP A 1 39  ? 372.475 355.302 307.537 1.00 141.74 ? 39  ASP B OD2   1 
ATOM   300   N  N     . SER A 1 40  ? 376.290 353.585 306.283 1.00 141.50 ? 40  SER B N     1 
ATOM   301   C  CA    . SER A 1 40  ? 377.009 354.027 305.095 1.00 137.01 ? 40  SER B CA    1 
ATOM   302   C  C     . SER A 1 40  ? 378.338 353.298 304.962 1.00 134.21 ? 40  SER B C     1 
ATOM   303   O  O     . SER A 1 40  ? 379.058 353.101 305.945 1.00 137.75 ? 40  SER B O     1 
ATOM   304   C  CB    . SER A 1 40  ? 377.252 355.536 305.144 1.00 136.11 ? 40  SER B CB    1 
ATOM   305   O  OG    . SER A 1 40  ? 376.027 356.245 305.189 1.00 139.30 ? 40  SER B OG    1 
ATOM   306   N  N     . ASP A 1 41  ? 378.655 352.897 303.730 1.00 125.07 ? 41  ASP B N     1 
ATOM   307   C  CA    . ASP A 1 41  ? 379.932 352.255 303.447 1.00 128.49 ? 41  ASP B CA    1 
ATOM   308   C  C     . ASP A 1 41  ? 381.091 353.245 303.537 1.00 127.96 ? 41  ASP B C     1 
ATOM   309   O  O     . ASP A 1 41  ? 382.222 352.838 303.824 1.00 128.53 ? 41  ASP B O     1 
ATOM   310   C  CB    . ASP A 1 41  ? 379.872 351.616 302.054 1.00 128.58 ? 41  ASP B CB    1 
ATOM   311   C  CG    . ASP A 1 41  ? 381.049 350.693 301.760 1.00 128.47 ? 41  ASP B CG    1 
ATOM   312   O  OD1   . ASP A 1 41  ? 381.919 350.494 302.632 1.00 126.84 ? 41  ASP B OD1   1 
ATOM   313   O  OD2   . ASP A 1 41  ? 381.101 350.159 300.633 1.00 129.10 ? 41  ASP B OD2   1 
ATOM   314   N  N     . LEU A 1 42  ? 380.831 354.538 303.319 1.00 119.57 ? 42  LEU B N     1 
ATOM   315   C  CA    . LEU A 1 42  ? 381.888 355.540 303.414 1.00 121.43 ? 42  LEU B CA    1 
ATOM   316   C  C     . LEU A 1 42  ? 382.461 355.631 304.825 1.00 119.43 ? 42  LEU B C     1 
ATOM   317   O  O     . LEU A 1 42  ? 383.616 356.035 304.999 1.00 118.20 ? 42  LEU B O     1 
ATOM   318   C  CB    . LEU A 1 42  ? 381.358 356.905 302.967 1.00 118.05 ? 42  LEU B CB    1 
ATOM   319   C  CG    . LEU A 1 42  ? 380.814 356.998 301.537 1.00 116.52 ? 42  LEU B CG    1 
ATOM   320   C  CD1   . LEU A 1 42  ? 380.005 358.271 301.346 1.00 116.40 ? 42  LEU B CD1   1 
ATOM   321   C  CD2   . LEU A 1 42  ? 381.942 356.920 300.518 1.00 117.74 ? 42  LEU B CD2   1 
ATOM   322   N  N     . GLN A 1 43  ? 381.672 355.269 305.840 1.00 111.57 ? 43  GLN B N     1 
ATOM   323   C  CA    . GLN A 1 43  ? 382.186 355.230 307.204 1.00 110.55 ? 43  GLN B CA    1 
ATOM   324   C  C     . GLN A 1 43  ? 383.300 354.200 307.340 1.00 106.69 ? 43  GLN B C     1 
ATOM   325   O  O     . GLN A 1 43  ? 384.336 354.471 307.956 1.00 108.76 ? 43  GLN B O     1 
ATOM   326   C  CB    . GLN A 1 43  ? 381.043 354.919 308.172 1.00 108.14 ? 43  GLN B CB    1 
ATOM   327   C  CG    . GLN A 1 43  ? 379.978 356.005 308.241 1.00 106.56 ? 43  GLN B CG    1 
ATOM   328   C  CD    . GLN A 1 43  ? 378.734 355.559 308.981 1.00 108.43 ? 43  GLN B CD    1 
ATOM   329   O  OE1   . GLN A 1 43  ? 378.259 354.439 308.800 1.00 113.32 ? 43  GLN B OE1   1 
ATOM   330   N  NE2   . GLN A 1 43  ? 378.192 356.441 309.812 1.00 112.27 ? 43  GLN B NE2   1 
ATOM   331   N  N     . LEU A 1 44  ? 383.103 353.012 306.765 1.00 101.65 ? 44  LEU B N     1 
ATOM   332   C  CA    . LEU A 1 44  ? 384.128 351.974 306.749 1.00 104.99 ? 44  LEU B CA    1 
ATOM   333   C  C     . LEU A 1 44  ? 385.235 352.215 305.736 1.00 109.68 ? 44  LEU B C     1 
ATOM   334   O  O     . LEU A 1 44  ? 386.308 351.621 305.882 1.00 110.65 ? 44  LEU B O     1 
ATOM   335   C  CB    . LEU A 1 44  ? 383.493 350.607 306.457 1.00 107.26 ? 44  LEU B CB    1 
ATOM   336   C  CG    . LEU A 1 44  ? 382.610 349.846 307.463 1.00 109.04 ? 44  LEU B CG    1 
ATOM   337   C  CD1   . LEU A 1 44  ? 382.786 348.355 307.251 1.00 111.62 ? 44  LEU B CD1   1 
ATOM   338   C  CD2   . LEU A 1 44  ? 382.959 350.151 308.912 1.00 106.70 ? 44  LEU B CD2   1 
ATOM   339   N  N     . ASP A 1 45  ? 384.994 353.024 304.702 1.00 117.85 ? 45  ASP B N     1 
ATOM   340   C  CA    . ASP A 1 45  ? 386.019 353.219 303.678 1.00 118.67 ? 45  ASP B CA    1 
ATOM   341   C  C     . ASP A 1 45  ? 387.275 353.866 304.253 1.00 117.15 ? 45  ASP B C     1 
ATOM   342   O  O     . ASP A 1 45  ? 388.396 353.469 303.910 1.00 111.98 ? 45  ASP B O     1 
ATOM   343   C  CB    . ASP A 1 45  ? 385.467 354.053 302.522 1.00 115.89 ? 45  ASP B CB    1 
ATOM   344   C  CG    . ASP A 1 45  ? 384.373 353.336 301.753 1.00 121.56 ? 45  ASP B CG    1 
ATOM   345   O  OD1   . ASP A 1 45  ? 384.119 352.145 302.033 1.00 122.65 ? 45  ASP B OD1   1 
ATOM   346   O  OD2   . ASP A 1 45  ? 383.768 353.963 300.862 1.00 122.76 ? 45  ASP B OD2   1 
ATOM   347   N  N     . ARG A 1 46  ? 387.106 354.858 305.133 1.00 110.84 ? 46  ARG B N     1 
ATOM   348   C  CA    . ARG A 1 46  ? 388.207 355.596 305.748 1.00 108.51 ? 46  ARG B CA    1 
ATOM   349   C  C     . ARG A 1 46  ? 388.281 355.393 307.260 1.00 107.97 ? 46  ARG B C     1 
ATOM   350   O  O     . ARG A 1 46  ? 388.817 356.252 307.968 1.00 105.55 ? 46  ARG B O     1 
ATOM   351   C  CB    . ARG A 1 46  ? 388.085 357.088 305.425 1.00 108.35 ? 46  ARG B CB    1 
ATOM   352   C  CG    . ARG A 1 46  ? 388.080 357.443 303.936 1.00 109.68 ? 46  ARG B CG    1 
ATOM   353   C  CD    . ARG A 1 46  ? 389.468 357.340 303.314 1.00 108.94 ? 46  ARG B CD    1 
ATOM   354   N  NE    . ARG A 1 46  ? 389.401 357.138 301.871 1.00 107.66 ? 46  ARG B NE    1 
ATOM   355   C  CZ    . ARG A 1 46  ? 390.374 356.642 301.115 1.00 108.11 ? 46  ARG B CZ    1 
ATOM   356   N  NH1   . ARG A 1 46  ? 391.557 356.312 301.615 1.00 107.92 ? 46  ARG B NH1   1 
ATOM   357   N  NH2   . ARG A 1 46  ? 390.160 356.479 299.814 1.00 110.32 ? 46  ARG B NH2   1 
ATOM   358   N  N     . ILE A 1 47  ? 387.762 354.275 307.774 1.00 108.57 ? 47  ILE B N     1 
ATOM   359   C  CA    . ILE A 1 47  ? 387.850 354.020 309.207 1.00 102.46 ? 47  ILE B CA    1 
ATOM   360   C  C     . ILE A 1 47  ? 389.285 353.767 309.652 1.00 99.84  ? 47  ILE B C     1 
ATOM   361   O  O     . ILE A 1 47  ? 389.602 353.950 310.832 1.00 106.20 ? 47  ILE B O     1 
ATOM   362   C  CB    . ILE A 1 47  ? 386.924 352.847 309.589 1.00 106.99 ? 47  ILE B CB    1 
ATOM   363   C  CG1   . ILE A 1 47  ? 386.536 352.921 311.068 1.00 102.52 ? 47  ILE B CG1   1 
ATOM   364   C  CG2   . ILE A 1 47  ? 387.558 351.496 309.248 1.00 106.27 ? 47  ILE B CG2   1 
ATOM   365   C  CD1   . ILE A 1 47  ? 385.388 353.866 311.345 1.00 102.73 ? 47  ILE B CD1   1 
ATOM   366   N  N     . SER A 1 48  ? 390.174 353.366 308.739 1.00 94.53  ? 48  SER B N     1 
ATOM   367   C  CA    . SER A 1 48  ? 391.572 353.140 309.087 1.00 99.75  ? 48  SER B CA    1 
ATOM   368   C  C     . SER A 1 48  ? 392.317 354.415 309.466 1.00 99.59  ? 48  SER B C     1 
ATOM   369   O  O     . SER A 1 48  ? 393.425 354.316 310.004 1.00 98.67  ? 48  SER B O     1 
ATOM   370   C  CB    . SER A 1 48  ? 392.292 352.466 307.919 1.00 102.87 ? 48  SER B CB    1 
ATOM   371   O  OG    . SER A 1 48  ? 392.221 353.266 306.752 1.00 104.41 ? 48  SER B OG    1 
ATOM   372   N  N     . VAL A 1 49  ? 391.753 355.596 309.193 1.00 100.46 ? 49  VAL B N     1 
ATOM   373   C  CA    . VAL A 1 49  ? 392.427 356.852 309.517 1.00 98.40  ? 49  VAL B CA    1 
ATOM   374   C  C     . VAL A 1 49  ? 392.621 356.988 311.023 1.00 98.37  ? 49  VAL B C     1 
ATOM   375   O  O     . VAL A 1 49  ? 393.659 357.478 311.484 1.00 105.96 ? 49  VAL B O     1 
ATOM   376   C  CB    . VAL A 1 49  ? 391.634 358.040 308.938 1.00 97.99  ? 49  VAL B CB    1 
ATOM   377   C  CG1   . VAL A 1 49  ? 392.208 359.372 309.425 1.00 95.55  ? 49  VAL B CG1   1 
ATOM   378   C  CG2   . VAL A 1 49  ? 391.621 357.980 307.409 1.00 104.20 ? 49  VAL B CG2   1 
ATOM   379   N  N     . TYR A 1 50  ? 391.631 356.549 311.808 1.00 87.25  ? 50  TYR B N     1 
ATOM   380   C  CA    . TYR A 1 50  ? 391.617 356.680 313.261 1.00 81.85  ? 50  TYR B CA    1 
ATOM   381   C  C     . TYR A 1 50  ? 391.562 355.359 314.011 1.00 86.66  ? 50  TYR B C     1 
ATOM   382   O  O     . TYR A 1 50  ? 391.942 355.330 315.183 1.00 86.86  ? 50  TYR B O     1 
ATOM   383   C  CB    . TYR A 1 50  ? 390.414 357.529 313.703 1.00 84.56  ? 50  TYR B CB    1 
ATOM   384   C  CG    . TYR A 1 50  ? 390.676 359.018 313.774 1.00 85.81  ? 50  TYR B CG    1 
ATOM   385   C  CD1   . TYR A 1 50  ? 391.525 359.553 314.734 1.00 87.43  ? 50  TYR B CD1   1 
ATOM   386   C  CD2   . TYR A 1 50  ? 390.065 359.890 312.889 1.00 87.07  ? 50  TYR B CD2   1 
ATOM   387   C  CE1   . TYR A 1 50  ? 391.761 360.908 314.802 1.00 86.57  ? 50  TYR B CE1   1 
ATOM   388   C  CE2   . TYR A 1 50  ? 390.299 361.247 312.952 1.00 84.01  ? 50  TYR B CE2   1 
ATOM   389   C  CZ    . TYR A 1 50  ? 391.144 361.750 313.909 1.00 84.80  ? 50  TYR B CZ    1 
ATOM   390   O  OH    . TYR A 1 50  ? 391.374 363.103 313.969 1.00 96.53  ? 50  TYR B OH    1 
ATOM   391   N  N     . TYR A 1 51  ? 391.109 354.276 313.377 1.00 96.75  ? 51  TYR B N     1 
ATOM   392   C  CA    . TYR A 1 51  ? 390.869 352.996 314.030 1.00 93.43  ? 51  TYR B CA    1 
ATOM   393   C  C     . TYR A 1 51  ? 391.747 351.901 313.442 1.00 89.25  ? 51  TYR B C     1 
ATOM   394   O  O     . TYR A 1 51  ? 392.136 351.948 312.272 1.00 91.27  ? 51  TYR B O     1 
ATOM   395   C  CB    . TYR A 1 51  ? 389.401 352.584 313.902 1.00 93.52  ? 51  TYR B CB    1 
ATOM   396   C  CG    . TYR A 1 51  ? 388.454 353.451 314.694 1.00 90.95  ? 51  TYR B CG    1 
ATOM   397   C  CD1   . TYR A 1 51  ? 387.958 354.635 314.173 1.00 87.64  ? 51  TYR B CD1   1 
ATOM   398   C  CD2   . TYR A 1 51  ? 388.049 353.073 315.963 1.00 93.21  ? 51  TYR B CD2   1 
ATOM   399   C  CE1   . TYR A 1 51  ? 387.091 355.423 314.901 1.00 83.48  ? 51  TYR B CE1   1 
ATOM   400   C  CE2   . TYR A 1 51  ? 387.183 353.849 316.692 1.00 95.17  ? 51  TYR B CE2   1 
ATOM   401   C  CZ    . TYR A 1 51  ? 386.706 355.021 316.161 1.00 92.80  ? 51  TYR B CZ    1 
ATOM   402   O  OH    . TYR A 1 51  ? 385.842 355.790 316.904 1.00 100.19 ? 51  TYR B OH    1 
ATOM   403   N  N     . ASN A 1 52  ? 392.060 350.924 314.288 1.00 91.40  ? 52  ASN B N     1 
ATOM   404   C  CA    . ASN A 1 52  ? 392.676 349.667 313.890 1.00 98.15  ? 52  ASN B CA    1 
ATOM   405   C  C     . ASN A 1 52  ? 391.605 348.586 313.877 1.00 99.85  ? 52  ASN B C     1 
ATOM   406   O  O     . ASN A 1 52  ? 390.821 348.473 314.826 1.00 100.85 ? 52  ASN B O     1 
ATOM   407   C  CB    . ASN A 1 52  ? 393.800 349.279 314.852 1.00 102.31 ? 52  ASN B CB    1 
ATOM   408   C  CG    . ASN A 1 52  ? 394.924 350.290 314.874 1.00 105.65 ? 52  ASN B CG    1 
ATOM   409   O  OD1   . ASN A 1 52  ? 395.254 350.890 313.853 1.00 114.55 ? 52  ASN B OD1   1 
ATOM   410   N  ND2   . ASN A 1 52  ? 395.522 350.485 316.044 1.00 104.72 ? 52  ASN B ND2   1 
ATOM   411   N  N     . GLU A 1 53  ? 391.571 347.798 312.806 1.00 121.52 ? 53  GLU B N     1 
ATOM   412   C  CA    . GLU A 1 53  ? 390.576 346.739 312.647 1.00 123.63 ? 53  GLU B CA    1 
ATOM   413   C  C     . GLU A 1 53  ? 391.081 345.506 313.387 1.00 127.63 ? 53  GLU B C     1 
ATOM   414   O  O     . GLU A 1 53  ? 391.937 344.774 312.886 1.00 132.88 ? 53  GLU B O     1 
ATOM   415   C  CB    . GLU A 1 53  ? 390.327 346.463 311.166 1.00 124.75 ? 53  GLU B CB    1 
ATOM   416   C  CG    . GLU A 1 53  ? 389.648 345.129 310.813 1.00 127.81 ? 53  GLU B CG    1 
ATOM   417   C  CD    . GLU A 1 53  ? 388.360 344.870 311.579 1.00 129.26 ? 53  GLU B CD    1 
ATOM   418   O  OE1   . GLU A 1 53  ? 387.754 345.830 312.096 1.00 125.07 ? 53  GLU B OE1   1 
ATOM   419   O  OE2   . GLU A 1 53  ? 387.945 343.694 311.653 1.00 127.87 ? 53  GLU B OE2   1 
ATOM   420   N  N     . ALA A 1 54  ? 390.551 345.279 314.587 1.00 131.72 ? 54  ALA B N     1 
ATOM   421   C  CA    . ALA A 1 54  ? 390.863 344.080 315.347 1.00 129.46 ? 54  ALA B CA    1 
ATOM   422   C  C     . ALA A 1 54  ? 390.030 342.906 314.839 1.00 132.54 ? 54  ALA B C     1 
ATOM   423   O  O     . ALA A 1 54  ? 389.119 343.061 314.022 1.00 137.24 ? 54  ALA B O     1 
ATOM   424   C  CB    . ALA A 1 54  ? 390.614 344.306 316.836 1.00 130.44 ? 54  ALA B CB    1 
ATOM   425   N  N     . THR A 1 55  ? 390.358 341.715 315.332 1.00 152.76 ? 55  THR B N     1 
ATOM   426   C  CA    . THR A 1 55  ? 389.673 340.507 314.894 1.00 156.08 ? 55  THR B CA    1 
ATOM   427   C  C     . THR A 1 55  ? 388.208 340.533 315.316 1.00 157.96 ? 55  THR B C     1 
ATOM   428   O  O     . THR A 1 55  ? 387.850 341.050 316.378 1.00 157.79 ? 55  THR B O     1 
ATOM   429   C  CB    . THR A 1 55  ? 390.359 339.259 315.460 1.00 154.57 ? 55  THR B CB    1 
ATOM   430   O  OG1   . THR A 1 55  ? 389.783 338.088 314.869 1.00 153.91 ? 55  THR B OG1   1 
ATOM   431   C  CG2   . THR A 1 55  ? 390.207 339.172 316.983 1.00 154.36 ? 55  THR B CG2   1 
ATOM   432   N  N     . GLY A 1 56  ? 387.356 339.969 314.463 1.00 154.94 ? 56  GLY B N     1 
ATOM   433   C  CA    . GLY A 1 56  ? 385.932 339.939 314.729 1.00 151.50 ? 56  GLY B CA    1 
ATOM   434   C  C     . GLY A 1 56  ? 385.196 341.224 314.430 1.00 151.91 ? 56  GLY B C     1 
ATOM   435   O  O     . GLY A 1 56  ? 384.088 341.419 314.939 1.00 151.98 ? 56  GLY B O     1 
ATOM   436   N  N     . GLY A 1 57  ? 385.772 342.111 313.621 1.00 133.99 ? 57  GLY B N     1 
ATOM   437   C  CA    . GLY A 1 57  ? 385.114 343.353 313.271 1.00 133.42 ? 57  GLY B CA    1 
ATOM   438   C  C     . GLY A 1 57  ? 385.150 344.432 314.330 1.00 133.26 ? 57  GLY B C     1 
ATOM   439   O  O     . GLY A 1 57  ? 384.480 345.457 314.164 1.00 131.89 ? 57  GLY B O     1 
ATOM   440   N  N     . LYS A 1 58  ? 385.905 344.240 315.410 1.00 128.28 ? 58  LYS B N     1 
ATOM   441   C  CA    . LYS A 1 58  ? 386.007 345.243 316.461 1.00 125.58 ? 58  LYS B CA    1 
ATOM   442   C  C     . LYS A 1 58  ? 387.036 346.292 316.061 1.00 124.08 ? 58  LYS B C     1 
ATOM   443   O  O     . LYS A 1 58  ? 388.133 345.952 315.606 1.00 128.51 ? 58  LYS B O     1 
ATOM   444   C  CB    . LYS A 1 58  ? 386.397 344.579 317.781 1.00 126.54 ? 58  LYS B CB    1 
ATOM   445   C  CG    . LYS A 1 58  ? 385.986 345.349 319.019 1.00 124.92 ? 58  LYS B CG    1 
ATOM   446   C  CD    . LYS A 1 58  ? 386.595 344.730 320.266 1.00 129.53 ? 58  LYS B CD    1 
ATOM   447   C  CE    . LYS A 1 58  ? 385.993 345.306 321.535 1.00 128.39 ? 58  LYS B CE    1 
ATOM   448   N  NZ    . LYS A 1 58  ? 384.664 344.707 321.841 1.00 125.72 ? 58  LYS B NZ    1 
ATOM   449   N  N     . TYR A 1 59  ? 386.677 347.565 316.224 1.00 104.64 ? 59  TYR B N     1 
ATOM   450   C  CA    . TYR A 1 59  ? 387.499 348.698 315.801 1.00 106.43 ? 59  TYR B CA    1 
ATOM   451   C  C     . TYR A 1 59  ? 388.062 349.383 317.038 1.00 103.57 ? 59  TYR B C     1 
ATOM   452   O  O     . TYR A 1 59  ? 387.310 349.969 317.824 1.00 100.60 ? 59  TYR B O     1 
ATOM   453   C  CB    . TYR A 1 59  ? 386.677 349.670 314.961 1.00 102.33 ? 59  TYR B CB    1 
ATOM   454   C  CG    . TYR A 1 59  ? 386.323 349.121 313.600 1.00 104.84 ? 59  TYR B CG    1 
ATOM   455   C  CD1   . TYR A 1 59  ? 387.228 349.178 312.550 1.00 105.57 ? 59  TYR B CD1   1 
ATOM   456   C  CD2   . TYR A 1 59  ? 385.088 348.531 313.369 1.00 107.49 ? 59  TYR B CD2   1 
ATOM   457   C  CE1   . TYR A 1 59  ? 386.911 348.672 311.306 1.00 107.69 ? 59  TYR B CE1   1 
ATOM   458   C  CE2   . TYR A 1 59  ? 384.762 348.022 312.128 1.00 110.22 ? 59  TYR B CE2   1 
ATOM   459   C  CZ    . TYR A 1 59  ? 385.678 348.094 311.100 1.00 112.60 ? 59  TYR B CZ    1 
ATOM   460   O  OH    . TYR A 1 59  ? 385.359 347.588 309.861 1.00 115.73 ? 59  TYR B OH    1 
ATOM   461   N  N     . VAL A 1 60  ? 389.380 349.311 317.202 1.00 99.13  ? 60  VAL B N     1 
ATOM   462   C  CA    . VAL A 1 60  ? 390.063 349.873 318.365 1.00 98.10  ? 60  VAL B CA    1 
ATOM   463   C  C     . VAL A 1 60  ? 390.487 351.291 317.980 1.00 98.31  ? 60  VAL B C     1 
ATOM   464   O  O     . VAL A 1 60  ? 391.125 351.453 316.934 1.00 103.09 ? 60  VAL B O     1 
ATOM   465   C  CB    . VAL A 1 60  ? 391.258 348.994 318.781 1.00 102.80 ? 60  VAL B CB    1 
ATOM   466   C  CG1   . VAL A 1 60  ? 392.368 349.793 319.483 1.00 102.44 ? 60  VAL B CG1   1 
ATOM   467   C  CG2   . VAL A 1 60  ? 390.789 347.854 319.675 1.00 105.96 ? 60  VAL B CG2   1 
ATOM   468   N  N     . PRO A 1 61  ? 390.176 352.342 318.745 1.00 94.25  ? 61  PRO B N     1 
ATOM   469   C  CA    . PRO A 1 61  ? 390.677 353.671 318.378 1.00 91.64  ? 61  PRO B CA    1 
ATOM   470   C  C     . PRO A 1 61  ? 392.187 353.750 318.489 1.00 99.19  ? 61  PRO B C     1 
ATOM   471   O  O     . PRO A 1 61  ? 392.801 353.136 319.364 1.00 102.96 ? 61  PRO B O     1 
ATOM   472   C  CB    . PRO A 1 61  ? 390.011 354.603 319.397 1.00 86.11  ? 61  PRO B CB    1 
ATOM   473   C  CG    . PRO A 1 61  ? 388.895 353.839 319.962 1.00 99.41  ? 61  PRO B CG    1 
ATOM   474   C  CD    . PRO A 1 61  ? 389.348 352.425 319.957 1.00 104.19 ? 61  PRO B CD    1 
ATOM   475   N  N     . ARG A 1 62  ? 392.783 354.529 317.589 1.00 107.87 ? 62  ARG B N     1 
ATOM   476   C  CA    . ARG A 1 62  ? 394.220 354.799 317.631 1.00 106.40 ? 62  ARG B CA    1 
ATOM   477   C  C     . ARG A 1 62  ? 394.493 355.978 318.570 1.00 102.60 ? 62  ARG B C     1 
ATOM   478   O  O     . ARG A 1 62  ? 394.964 357.045 318.174 1.00 109.18 ? 62  ARG B O     1 
ATOM   479   C  CB    . ARG A 1 62  ? 394.752 355.052 316.224 1.00 105.23 ? 62  ARG B CB    1 
ATOM   480   C  CG    . ARG A 1 62  ? 396.257 354.875 316.097 1.00 108.05 ? 62  ARG B CG    1 
ATOM   481   C  CD    . ARG A 1 62  ? 396.734 354.974 314.653 1.00 105.98 ? 62  ARG B CD    1 
ATOM   482   N  NE    . ARG A 1 62  ? 396.255 353.867 313.825 1.00 103.83 ? 62  ARG B NE    1 
ATOM   483   C  CZ    . ARG A 1 62  ? 395.234 353.901 312.973 1.00 103.24 ? 62  ARG B CZ    1 
ATOM   484   N  NH1   . ARG A 1 62  ? 394.476 354.978 312.821 1.00 107.22 ? 62  ARG B NH1   1 
ATOM   485   N  NH2   . ARG A 1 62  ? 394.953 352.815 312.260 1.00 105.86 ? 62  ARG B NH2   1 
ATOM   486   N  N     . ALA A 1 63  ? 394.188 355.747 319.849 1.00 91.32  ? 63  ALA B N     1 
ATOM   487   C  CA    . ALA A 1 63  ? 394.194 356.765 320.892 1.00 93.27  ? 63  ALA B CA    1 
ATOM   488   C  C     . ALA A 1 63  ? 395.151 356.363 321.999 1.00 93.51  ? 63  ALA B C     1 
ATOM   489   O  O     . ALA A 1 63  ? 395.288 355.178 322.310 1.00 93.02  ? 63  ALA B O     1 
ATOM   490   C  CB    . ALA A 1 63  ? 392.798 356.954 321.487 1.00 99.46  ? 63  ALA B CB    1 
ATOM   491   N  N     . ILE A 1 64  ? 395.840 357.356 322.559 1.00 108.86 ? 64  ILE B N     1 
ATOM   492   C  CA    . ILE A 1 64  ? 396.768 357.175 323.672 1.00 102.31 ? 64  ILE B CA    1 
ATOM   493   C  C     . ILE A 1 64  ? 396.269 358.059 324.807 1.00 103.91 ? 64  ILE B C     1 
ATOM   494   O  O     . ILE A 1 64  ? 396.145 359.276 324.634 1.00 110.63 ? 64  ILE B O     1 
ATOM   495   C  CB    . ILE A 1 64  ? 398.227 357.541 323.313 1.00 104.34 ? 64  ILE B CB    1 
ATOM   496   C  CG1   . ILE A 1 64  ? 398.917 356.562 322.335 1.00 107.41 ? 64  ILE B CG1   1 
ATOM   497   C  CG2   . ILE A 1 64  ? 399.100 357.617 324.583 1.00 99.57  ? 64  ILE B CG2   1 
ATOM   498   C  CD1   . ILE A 1 64  ? 398.248 356.221 321.023 1.00 111.53 ? 64  ILE B CD1   1 
ATOM   499   N  N     . LEU A 1 65  ? 396.016 357.454 325.968 1.00 100.71 ? 65  LEU B N     1 
ATOM   500   C  CA    . LEU A 1 65  ? 395.477 358.148 327.133 1.00 99.54  ? 65  LEU B CA    1 
ATOM   501   C  C     . LEU A 1 65  ? 396.565 358.265 328.188 1.00 100.79 ? 65  LEU B C     1 
ATOM   502   O  O     . LEU A 1 65  ? 397.147 357.255 328.594 1.00 106.63 ? 65  LEU B O     1 
ATOM   503   C  CB    . LEU A 1 65  ? 394.259 357.415 327.698 1.00 101.73 ? 65  LEU B CB    1 
ATOM   504   C  CG    . LEU A 1 65  ? 393.084 357.303 326.722 1.00 103.57 ? 65  LEU B CG    1 
ATOM   505   C  CD1   . LEU A 1 65  ? 393.113 355.992 325.929 1.00 109.20 ? 65  LEU B CD1   1 
ATOM   506   C  CD2   . LEU A 1 65  ? 391.753 357.494 327.431 1.00 102.85 ? 65  LEU B CD2   1 
ATOM   507   N  N     . VAL A 1 66  ? 396.826 359.496 328.627 1.00 100.30 ? 66  VAL B N     1 
ATOM   508   C  CA    . VAL A 1 66  ? 397.936 359.819 329.518 1.00 100.19 ? 66  VAL B CA    1 
ATOM   509   C  C     . VAL A 1 66  ? 397.408 360.681 330.652 1.00 101.77 ? 66  VAL B C     1 
ATOM   510   O  O     . VAL A 1 66  ? 396.654 361.631 330.418 1.00 108.62 ? 66  VAL B O     1 
ATOM   511   C  CB    . VAL A 1 66  ? 399.073 360.559 328.786 1.00 99.12  ? 66  VAL B CB    1 
ATOM   512   C  CG1   . VAL A 1 66  ? 400.328 360.628 329.666 1.00 97.56  ? 66  VAL B CG1   1 
ATOM   513   C  CG2   . VAL A 1 66  ? 399.380 359.903 327.445 1.00 103.94 ? 66  VAL B CG2   1 
ATOM   514   N  N     . ASP A 1 67  ? 397.802 360.348 331.878 1.00 116.38 ? 67  ASP B N     1 
ATOM   515   C  CA    . ASP A 1 67  ? 397.611 361.236 333.015 1.00 120.20 ? 67  ASP B CA    1 
ATOM   516   C  C     . ASP A 1 67  ? 398.424 360.715 334.185 1.00 117.29 ? 67  ASP B C     1 
ATOM   517   O  O     . ASP A 1 67  ? 398.428 359.515 334.459 1.00 121.12 ? 67  ASP B O     1 
ATOM   518   C  CB    . ASP A 1 67  ? 396.132 361.360 333.423 1.00 123.41 ? 67  ASP B CB    1 
ATOM   519   C  CG    . ASP A 1 67  ? 395.900 362.363 334.553 1.00 126.45 ? 67  ASP B CG    1 
ATOM   520   O  OD1   . ASP A 1 67  ? 396.896 362.967 334.994 1.00 124.96 ? 67  ASP B OD1   1 
ATOM   521   O  OD2   . ASP A 1 67  ? 394.760 362.541 335.029 1.00 128.00 ? 67  ASP B OD2   1 
ATOM   522   N  N     . LEU A 1 68  ? 399.104 361.632 334.868 1.00 106.48 ? 68  LEU B N     1 
ATOM   523   C  CA    . LEU A 1 68  ? 399.949 361.262 335.992 1.00 108.81 ? 68  LEU B CA    1 
ATOM   524   C  C     . LEU A 1 68  ? 399.142 360.871 337.225 1.00 114.70 ? 68  LEU B C     1 
ATOM   525   O  O     . LEU A 1 68  ? 399.700 360.240 338.130 1.00 119.48 ? 68  LEU B O     1 
ATOM   526   C  CB    . LEU A 1 68  ? 400.898 362.417 336.319 1.00 108.32 ? 68  LEU B CB    1 
ATOM   527   C  CG    . LEU A 1 68  ? 401.808 362.874 335.171 1.00 109.26 ? 68  LEU B CG    1 
ATOM   528   C  CD1   . LEU A 1 68  ? 402.470 364.194 335.510 1.00 112.24 ? 68  LEU B CD1   1 
ATOM   529   C  CD2   . LEU A 1 68  ? 402.841 361.806 334.836 1.00 112.16 ? 68  LEU B CD2   1 
ATOM   530   N  N     . GLU A 1 69  ? 397.832 361.240 337.286 1.00 118.66 ? 69  GLU B N     1 
ATOM   531   C  CA    . GLU A 1 69  ? 396.884 360.801 338.303 1.00 115.06 ? 69  GLU B CA    1 
ATOM   532   C  C     . GLU A 1 69  ? 395.824 359.900 337.666 1.00 119.22 ? 69  GLU B C     1 
ATOM   533   O  O     . GLU A 1 69  ? 395.350 360.210 336.569 1.00 123.60 ? 69  GLU B O     1 
ATOM   534   C  CB    . GLU A 1 69  ? 396.196 361.996 338.979 1.00 121.29 ? 69  GLU B CB    1 
ATOM   535   C  CG    . GLU A 1 69  ? 395.362 362.884 338.051 1.00 127.72 ? 69  GLU B CG    1 
ATOM   536   C  CD    . GLU A 1 69  ? 394.884 364.150 338.734 1.00 129.54 ? 69  GLU B CD    1 
ATOM   537   O  OE1   . GLU A 1 69  ? 394.893 364.193 339.982 1.00 130.02 ? 69  GLU B OE1   1 
ATOM   538   O  OE2   . GLU A 1 69  ? 394.497 365.102 338.023 1.00 127.36 ? 69  GLU B OE2   1 
ATOM   539   N  N     . PRO A 1 70  ? 395.401 358.806 338.303 1.00 108.11 ? 70  PRO B N     1 
ATOM   540   C  CA    . PRO A 1 70  ? 394.553 357.836 337.600 1.00 111.40 ? 70  PRO B CA    1 
ATOM   541   C  C     . PRO A 1 70  ? 393.059 358.125 337.622 1.00 111.97 ? 70  PRO B C     1 
ATOM   542   O  O     . PRO A 1 70  ? 392.305 357.348 337.028 1.00 112.10 ? 70  PRO B O     1 
ATOM   543   C  CB    . PRO A 1 70  ? 394.854 356.546 338.367 1.00 106.90 ? 70  PRO B CB    1 
ATOM   544   C  CG    . PRO A 1 70  ? 395.006 357.005 339.769 1.00 107.51 ? 70  PRO B CG    1 
ATOM   545   C  CD    . PRO A 1 70  ? 395.573 358.410 339.716 1.00 104.16 ? 70  PRO B CD    1 
ATOM   546   N  N     . GLY A 1 71  ? 392.617 359.202 338.276 1.00 109.75 ? 71  GLY B N     1 
ATOM   547   C  CA    . GLY A 1 71  ? 391.191 359.387 338.506 1.00 105.46 ? 71  GLY B CA    1 
ATOM   548   C  C     . GLY A 1 71  ? 390.395 359.585 337.229 1.00 110.51 ? 71  GLY B C     1 
ATOM   549   O  O     . GLY A 1 71  ? 389.375 358.923 337.008 1.00 112.74 ? 71  GLY B O     1 
ATOM   550   N  N     . THR A 1 72  ? 390.858 360.483 336.358 1.00 119.18 ? 72  THR B N     1 
ATOM   551   C  CA    . THR A 1 72  ? 390.091 360.772 335.153 1.00 122.10 ? 72  THR B CA    1 
ATOM   552   C  C     . THR A 1 72  ? 390.126 359.609 334.167 1.00 122.83 ? 72  THR B C     1 
ATOM   553   O  O     . THR A 1 72  ? 389.123 359.344 333.498 1.00 126.00 ? 72  THR B O     1 
ATOM   554   C  CB    . THR A 1 72  ? 390.586 362.065 334.496 1.00 120.44 ? 72  THR B CB    1 
ATOM   555   O  OG1   . THR A 1 72  ? 389.689 362.442 333.444 1.00 121.21 ? 72  THR B OG1   1 
ATOM   556   C  CG2   . THR A 1 72  ? 391.981 361.924 333.923 1.00 122.91 ? 72  THR B CG2   1 
ATOM   557   N  N     . MET A 1 73  ? 391.247 358.890 334.067 1.00 111.77 ? 73  MET B N     1 
ATOM   558   C  CA    . MET A 1 73  ? 391.266 357.733 333.178 1.00 112.93 ? 73  MET B CA    1 
ATOM   559   C  C     . MET A 1 73  ? 390.418 356.599 333.730 1.00 115.96 ? 73  MET B C     1 
ATOM   560   O  O     . MET A 1 73  ? 389.826 355.838 332.960 1.00 111.89 ? 73  MET B O     1 
ATOM   561   C  CB    . MET A 1 73  ? 392.687 357.238 332.926 1.00 112.37 ? 73  MET B CB    1 
ATOM   562   C  CG    . MET A 1 73  ? 393.399 357.968 331.808 1.00 112.04 ? 73  MET B CG    1 
ATOM   563   S  SD    . MET A 1 73  ? 395.147 358.155 332.136 1.00 121.38 ? 73  MET B SD    1 
ATOM   564   C  CE    . MET A 1 73  ? 395.681 356.498 331.720 1.00 121.37 ? 73  MET B CE    1 
ATOM   565   N  N     . ASP A 1 74  ? 390.359 356.450 335.055 1.00 115.50 ? 74  ASP B N     1 
ATOM   566   C  CA    . ASP A 1 74  ? 389.430 355.482 335.628 1.00 113.98 ? 74  ASP B CA    1 
ATOM   567   C  C     . ASP A 1 74  ? 387.992 355.872 335.322 1.00 109.73 ? 74  ASP B C     1 
ATOM   568   O  O     . ASP A 1 74  ? 387.156 355.008 335.034 1.00 105.62 ? 74  ASP B O     1 
ATOM   569   C  CB    . ASP A 1 74  ? 389.645 355.360 337.137 1.00 114.86 ? 74  ASP B CB    1 
ATOM   570   C  CG    . ASP A 1 74  ? 390.972 354.716 337.493 1.00 117.77 ? 74  ASP B CG    1 
ATOM   571   O  OD1   . ASP A 1 74  ? 391.597 354.089 336.612 1.00 120.32 ? 74  ASP B OD1   1 
ATOM   572   O  OD2   . ASP A 1 74  ? 391.394 354.837 338.662 1.00 118.32 ? 74  ASP B OD2   1 
ATOM   573   N  N     . SER A 1 75  ? 387.692 357.172 335.360 1.00 107.62 ? 75  SER B N     1 
ATOM   574   C  CA    . SER A 1 75  ? 386.362 357.632 334.971 1.00 113.29 ? 75  SER B CA    1 
ATOM   575   C  C     . SER A 1 75  ? 386.071 357.314 333.508 1.00 115.14 ? 75  SER B C     1 
ATOM   576   O  O     . SER A 1 75  ? 384.961 356.892 333.165 1.00 120.56 ? 75  SER B O     1 
ATOM   577   C  CB    . SER A 1 75  ? 386.233 359.132 335.226 1.00 112.98 ? 75  SER B CB    1 
ATOM   578   O  OG    . SER A 1 75  ? 384.941 359.595 334.876 1.00 113.70 ? 75  SER B OG    1 
ATOM   579   N  N     . VAL A 1 76  ? 387.058 357.512 332.633 1.00 105.20 ? 76  VAL B N     1 
ATOM   580   C  CA    . VAL A 1 76  ? 386.870 357.215 331.215 1.00 106.54 ? 76  VAL B CA    1 
ATOM   581   C  C     . VAL A 1 76  ? 386.665 355.718 331.004 1.00 111.58 ? 76  VAL B C     1 
ATOM   582   O  O     . VAL A 1 76  ? 385.796 355.301 330.230 1.00 117.09 ? 76  VAL B O     1 
ATOM   583   C  CB    . VAL A 1 76  ? 388.060 357.753 330.396 1.00 104.70 ? 76  VAL B CB    1 
ATOM   584   C  CG1   . VAL A 1 76  ? 388.048 357.203 328.968 1.00 106.78 ? 76  VAL B CG1   1 
ATOM   585   C  CG2   . VAL A 1 76  ? 388.033 359.275 330.360 1.00 104.78 ? 76  VAL B CG2   1 
ATOM   586   N  N     . ARG A 1 77  ? 387.462 354.887 331.681 1.00 107.35 ? 77  ARG B N     1 
ATOM   587   C  CA    . ARG A 1 77  ? 387.320 353.442 331.538 1.00 105.48 ? 77  ARG B CA    1 
ATOM   588   C  C     . ARG A 1 77  ? 385.997 352.950 332.109 1.00 108.92 ? 77  ARG B C     1 
ATOM   589   O  O     . ARG A 1 77  ? 385.453 351.949 331.630 1.00 110.45 ? 77  ARG B O     1 
ATOM   590   C  CB    . ARG A 1 77  ? 388.485 352.722 332.221 1.00 108.71 ? 77  ARG B CB    1 
ATOM   591   C  CG    . ARG A 1 77  ? 388.859 351.410 331.549 1.00 111.05 ? 77  ARG B CG    1 
ATOM   592   C  CD    . ARG A 1 77  ? 389.902 350.619 332.331 1.00 112.78 ? 77  ARG B CD    1 
ATOM   593   N  NE    . ARG A 1 77  ? 391.189 351.306 332.422 1.00 113.49 ? 77  ARG B NE    1 
ATOM   594   C  CZ    . ARG A 1 77  ? 391.596 352.083 333.421 1.00 114.15 ? 77  ARG B CZ    1 
ATOM   595   N  NH1   . ARG A 1 77  ? 390.831 352.342 334.472 1.00 116.72 ? 77  ARG B NH1   1 
ATOM   596   N  NH2   . ARG A 1 77  ? 392.812 352.620 333.365 1.00 108.14 ? 77  ARG B NH2   1 
ATOM   597   N  N     . SER A 1 78  ? 385.474 353.625 333.132 1.00 111.56 ? 78  SER B N     1 
ATOM   598   C  CA    . SER A 1 78  ? 384.164 353.297 333.677 1.00 113.00 ? 78  SER B CA    1 
ATOM   599   C  C     . SER A 1 78  ? 383.016 353.877 332.861 1.00 112.51 ? 78  SER B C     1 
ATOM   600   O  O     . SER A 1 78  ? 381.875 353.436 333.034 1.00 118.39 ? 78  SER B O     1 
ATOM   601   C  CB    . SER A 1 78  ? 384.064 353.797 335.119 1.00 115.04 ? 78  SER B CB    1 
ATOM   602   O  OG    . SER A 1 78  ? 385.155 353.333 335.896 1.00 116.14 ? 78  SER B OG    1 
ATOM   603   N  N     . GLY A 1 79  ? 383.280 354.845 331.977 1.00 110.13 ? 79  GLY B N     1 
ATOM   604   C  CA    . GLY A 1 79  ? 382.239 355.424 331.178 1.00 111.13 ? 79  GLY B CA    1 
ATOM   605   C  C     . GLY A 1 79  ? 381.732 354.458 330.122 1.00 119.74 ? 79  GLY B C     1 
ATOM   606   O  O     . GLY A 1 79  ? 382.240 353.337 329.976 1.00 123.32 ? 79  GLY B O     1 
ATOM   607   N  N     . PRO A 1 80  ? 380.701 354.881 329.382 1.00 131.07 ? 80  PRO B N     1 
ATOM   608   C  CA    . PRO A 1 80  ? 380.145 353.997 328.342 1.00 132.14 ? 80  PRO B CA    1 
ATOM   609   C  C     . PRO A 1 80  ? 381.134 353.676 327.239 1.00 127.50 ? 80  PRO B C     1 
ATOM   610   O  O     . PRO A 1 80  ? 381.081 352.578 326.670 1.00 123.90 ? 80  PRO B O     1 
ATOM   611   C  CB    . PRO A 1 80  ? 378.944 354.792 327.813 1.00 129.33 ? 80  PRO B CB    1 
ATOM   612   C  CG    . PRO A 1 80  ? 379.284 356.211 328.081 1.00 123.91 ? 80  PRO B CG    1 
ATOM   613   C  CD    . PRO A 1 80  ? 380.095 356.224 329.344 1.00 124.96 ? 80  PRO B CD    1 
ATOM   614   N  N     . PHE A 1 81  ? 382.036 354.605 326.929 1.00 106.08 ? 81  PHE B N     1 
ATOM   615   C  CA    . PHE A 1 81  ? 383.100 354.424 325.943 1.00 102.18 ? 81  PHE B CA    1 
ATOM   616   C  C     . PHE A 1 81  ? 384.432 354.099 326.609 1.00 106.30 ? 81  PHE B C     1 
ATOM   617   O  O     . PHE A 1 81  ? 385.483 354.619 326.229 1.00 109.65 ? 81  PHE B O     1 
ATOM   618   C  CB    . PHE A 1 81  ? 383.206 355.662 325.057 1.00 102.91 ? 81  PHE B CB    1 
ATOM   619   C  CG    . PHE A 1 81  ? 382.033 355.839 324.139 1.00 102.72 ? 81  PHE B CG    1 
ATOM   620   C  CD1   . PHE A 1 81  ? 381.994 355.183 322.919 1.00 104.78 ? 81  PHE B CD1   1 
ATOM   621   C  CD2   . PHE A 1 81  ? 380.963 356.638 324.497 1.00 105.08 ? 81  PHE B CD2   1 
ATOM   622   C  CE1   . PHE A 1 81  ? 380.918 355.333 322.069 1.00 101.66 ? 81  PHE B CE1   1 
ATOM   623   C  CE2   . PHE A 1 81  ? 379.883 356.790 323.650 1.00 109.03 ? 81  PHE B CE2   1 
ATOM   624   C  CZ    . PHE A 1 81  ? 379.861 356.136 322.435 1.00 105.70 ? 81  PHE B CZ    1 
ATOM   625   N  N     . GLY A 1 82  ? 384.395 353.273 327.652 1.00 115.92 ? 82  GLY B N     1 
ATOM   626   C  CA    . GLY A 1 82  ? 385.597 352.735 328.258 1.00 113.83 ? 82  GLY B CA    1 
ATOM   627   C  C     . GLY A 1 82  ? 386.061 351.472 327.564 1.00 115.31 ? 82  GLY B C     1 
ATOM   628   O  O     . GLY A 1 82  ? 387.262 351.264 327.368 1.00 117.21 ? 82  GLY B O     1 
ATOM   629   N  N     . GLN A 1 83  ? 385.108 350.618 327.183 1.00 110.26 ? 83  GLN B N     1 
ATOM   630   C  CA    . GLN A 1 83  ? 385.441 349.376 326.494 1.00 110.28 ? 83  GLN B CA    1 
ATOM   631   C  C     . GLN A 1 83  ? 386.041 349.609 325.113 1.00 112.23 ? 83  GLN B C     1 
ATOM   632   O  O     . GLN A 1 83  ? 386.717 348.716 324.592 1.00 114.58 ? 83  GLN B O     1 
ATOM   633   C  CB    . GLN A 1 83  ? 384.191 348.504 326.354 1.00 115.90 ? 83  GLN B CB    1 
ATOM   634   C  CG    . GLN A 1 83  ? 384.480 347.025 326.155 1.00 122.88 ? 83  GLN B CG    1 
ATOM   635   C  CD    . GLN A 1 83  ? 383.223 346.210 325.917 1.00 125.14 ? 83  GLN B CD    1 
ATOM   636   O  OE1   . GLN A 1 83  ? 383.096 345.529 324.900 1.00 123.55 ? 83  GLN B OE1   1 
ATOM   637   N  NE2   . GLN A 1 83  ? 382.287 346.277 326.855 1.00 123.87 ? 83  GLN B NE2   1 
ATOM   638   N  N     . ILE A 1 84  ? 385.805 350.774 324.508 1.00 94.06  ? 84  ILE B N     1 
ATOM   639   C  CA    . ILE A 1 84  ? 386.184 350.978 323.113 1.00 97.26  ? 84  ILE B CA    1 
ATOM   640   C  C     . ILE A 1 84  ? 387.709 351.029 322.990 1.00 97.60  ? 84  ILE B C     1 
ATOM   641   O  O     . ILE A 1 84  ? 388.281 350.515 322.023 1.00 102.14 ? 84  ILE B O     1 
ATOM   642   C  CB    . ILE A 1 84  ? 385.492 352.251 322.566 1.00 95.56  ? 84  ILE B CB    1 
ATOM   643   C  CG1   . ILE A 1 84  ? 385.705 352.462 321.059 1.00 92.14  ? 84  ILE B CG1   1 
ATOM   644   C  CG2   . ILE A 1 84  ? 386.025 353.514 323.246 1.00 91.62  ? 84  ILE B CG2   1 
ATOM   645   C  CD1   . ILE A 1 84  ? 384.587 351.894 320.229 1.00 100.69 ? 84  ILE B CD1   1 
ATOM   646   N  N     . PHE A 1 85  ? 388.389 351.621 323.972 1.00 93.20  ? 85  PHE B N     1 
ATOM   647   C  CA    . PHE A 1 85  ? 389.838 351.767 323.935 1.00 94.27  ? 85  PHE B CA    1 
ATOM   648   C  C     . PHE A 1 85  ? 390.539 350.460 324.295 1.00 100.13 ? 85  PHE B C     1 
ATOM   649   O  O     . PHE A 1 85  ? 389.974 349.578 324.947 1.00 103.43 ? 85  PHE B O     1 
ATOM   650   C  CB    . PHE A 1 85  ? 390.298 352.865 324.897 1.00 93.10  ? 85  PHE B CB    1 
ATOM   651   C  CG    . PHE A 1 85  ? 389.740 354.223 324.590 1.00 89.92  ? 85  PHE B CG    1 
ATOM   652   C  CD1   . PHE A 1 85  ? 390.265 354.981 323.560 1.00 89.71  ? 85  PHE B CD1   1 
ATOM   653   C  CD2   . PHE A 1 85  ? 388.703 354.748 325.337 1.00 97.50  ? 85  PHE B CD2   1 
ATOM   654   C  CE1   . PHE A 1 85  ? 389.761 356.232 323.277 1.00 92.82  ? 85  PHE B CE1   1 
ATOM   655   C  CE2   . PHE A 1 85  ? 388.195 356.000 325.057 1.00 90.62  ? 85  PHE B CE2   1 
ATOM   656   C  CZ    . PHE A 1 85  ? 388.725 356.743 324.026 1.00 87.91  ? 85  PHE B CZ    1 
ATOM   657   N  N     . ARG A 1 86  ? 391.794 350.346 323.857 1.00 103.39 ? 86  ARG B N     1 
ATOM   658   C  CA    . ARG A 1 86  ? 392.632 349.240 324.298 1.00 105.18 ? 86  ARG B CA    1 
ATOM   659   C  C     . ARG A 1 86  ? 393.068 349.476 325.747 1.00 103.35 ? 86  ARG B C     1 
ATOM   660   O  O     . ARG A 1 86  ? 393.424 350.604 326.099 1.00 110.34 ? 86  ARG B O     1 
ATOM   661   C  CB    . ARG A 1 86  ? 393.870 349.095 323.411 1.00 104.98 ? 86  ARG B CB    1 
ATOM   662   C  CG    . ARG A 1 86  ? 394.565 347.744 323.577 1.00 108.25 ? 86  ARG B CG    1 
ATOM   663   C  CD    . ARG A 1 86  ? 395.790 347.558 322.683 1.00 107.35 ? 86  ARG B CD    1 
ATOM   664   N  NE    . ARG A 1 86  ? 395.446 347.329 321.280 1.00 112.88 ? 86  ARG B NE    1 
ATOM   665   C  CZ    . ARG A 1 86  ? 395.534 348.206 320.285 1.00 113.01 ? 86  ARG B CZ    1 
ATOM   666   N  NH1   . ARG A 1 86  ? 395.915 349.462 320.478 1.00 113.32 ? 86  ARG B NH1   1 
ATOM   667   N  NH2   . ARG A 1 86  ? 395.216 347.816 319.054 1.00 109.26 ? 86  ARG B NH2   1 
ATOM   668   N  N     . PRO A 1 87  ? 393.046 348.451 326.618 1.00 90.85  ? 87  PRO B N     1 
ATOM   669   C  CA    . PRO A 1 87  ? 393.535 348.682 327.991 1.00 93.50  ? 87  PRO B CA    1 
ATOM   670   C  C     . PRO A 1 87  ? 395.007 349.049 328.074 1.00 98.42  ? 87  PRO B C     1 
ATOM   671   O  O     . PRO A 1 87  ? 395.399 349.783 328.989 1.00 101.56 ? 87  PRO B O     1 
ATOM   672   C  CB    . PRO A 1 87  ? 393.258 347.346 328.695 1.00 98.17  ? 87  PRO B CB    1 
ATOM   673   C  CG    . PRO A 1 87  ? 392.213 346.701 327.897 1.00 99.33  ? 87  PRO B CG    1 
ATOM   674   C  CD    . PRO A 1 87  ? 392.504 347.083 326.491 1.00 94.44  ? 87  PRO B CD    1 
ATOM   675   N  N     . ASP A 1 88  ? 395.834 348.553 327.151 1.00 118.04 ? 88  ASP B N     1 
ATOM   676   C  CA    . ASP A 1 88  ? 397.276 348.763 327.239 1.00 120.72 ? 88  ASP B CA    1 
ATOM   677   C  C     . ASP A 1 88  ? 397.631 350.237 327.056 1.00 121.53 ? 88  ASP B C     1 
ATOM   678   O  O     . ASP A 1 88  ? 398.564 350.733 327.697 1.00 121.33 ? 88  ASP B O     1 
ATOM   679   C  CB    . ASP A 1 88  ? 397.974 347.891 326.187 1.00 123.02 ? 88  ASP B CB    1 
ATOM   680   C  CG    . ASP A 1 88  ? 399.497 347.833 326.346 1.00 127.06 ? 88  ASP B CG    1 
ATOM   681   O  OD1   . ASP A 1 88  ? 400.097 346.912 325.755 1.00 130.15 ? 88  ASP B OD1   1 
ATOM   682   O  OD2   . ASP A 1 88  ? 400.105 348.651 327.066 1.00 127.81 ? 88  ASP B OD2   1 
ATOM   683   N  N     . ASN A 1 89  ? 396.888 350.956 326.214 1.00 114.73 ? 89  ASN B N     1 
ATOM   684   C  CA    . ASN A 1 89  ? 397.179 352.362 325.958 1.00 106.38 ? 89  ASN B CA    1 
ATOM   685   C  C     . ASN A 1 89  ? 396.981 353.249 327.182 1.00 104.92 ? 89  ASN B C     1 
ATOM   686   O  O     . ASN A 1 89  ? 397.523 354.359 327.208 1.00 109.95 ? 89  ASN B O     1 
ATOM   687   C  CB    . ASN A 1 89  ? 396.297 352.873 324.816 1.00 112.06 ? 89  ASN B CB    1 
ATOM   688   C  CG    . ASN A 1 89  ? 396.749 352.377 323.452 1.00 114.91 ? 89  ASN B CG    1 
ATOM   689   O  OD1   . ASN A 1 89  ? 397.911 352.023 323.252 1.00 113.48 ? 89  ASN B OD1   1 
ATOM   690   N  ND2   . ASN A 1 89  ? 395.820 352.343 322.504 1.00 116.04 ? 89  ASN B ND2   1 
ATOM   691   N  N     . PHE A 1 90  ? 396.231 352.801 328.188 1.00 99.36  ? 90  PHE B N     1 
ATOM   692   C  CA    . PHE A 1 90  ? 396.037 353.570 329.415 1.00 99.36  ? 90  PHE B CA    1 
ATOM   693   C  C     . PHE A 1 90  ? 397.339 353.533 330.201 1.00 108.76 ? 90  PHE B C     1 
ATOM   694   O  O     . PHE A 1 90  ? 397.637 352.544 330.875 1.00 116.17 ? 90  PHE B O     1 
ATOM   695   C  CB    . PHE A 1 90  ? 394.897 352.993 330.245 1.00 104.91 ? 90  PHE B CB    1 
ATOM   696   C  CG    . PHE A 1 90  ? 393.543 353.156 329.622 1.00 106.70 ? 90  PHE B CG    1 
ATOM   697   C  CD1   . PHE A 1 90  ? 393.106 352.273 328.653 1.00 110.41 ? 90  PHE B CD1   1 
ATOM   698   C  CD2   . PHE A 1 90  ? 392.704 354.182 330.013 1.00 104.96 ? 90  PHE B CD2   1 
ATOM   699   C  CE1   . PHE A 1 90  ? 391.862 352.413 328.080 1.00 109.58 ? 90  PHE B CE1   1 
ATOM   700   C  CE2   . PHE A 1 90  ? 391.455 354.324 329.444 1.00 103.99 ? 90  PHE B CE2   1 
ATOM   701   C  CZ    . PHE A 1 90  ? 391.036 353.440 328.475 1.00 105.85 ? 90  PHE B CZ    1 
ATOM   702   N  N     . VAL A 1 91  ? 398.118 354.609 330.108 1.00 108.58 ? 91  VAL B N     1 
ATOM   703   C  CA    . VAL A 1 91  ? 399.405 354.738 330.786 1.00 109.62 ? 91  VAL B CA    1 
ATOM   704   C  C     . VAL A 1 91  ? 399.293 355.872 331.801 1.00 107.23 ? 91  VAL B C     1 
ATOM   705   O  O     . VAL A 1 91  ? 398.800 356.960 331.477 1.00 110.99 ? 91  VAL B O     1 
ATOM   706   C  CB    . VAL A 1 91  ? 400.544 354.967 329.770 1.00 108.21 ? 91  VAL B CB    1 
ATOM   707   C  CG1   . VAL A 1 91  ? 400.503 356.366 329.162 1.00 107.06 ? 91  VAL B CG1   1 
ATOM   708   C  CG2   . VAL A 1 91  ? 401.904 354.667 330.397 1.00 108.76 ? 91  VAL B CG2   1 
ATOM   709   N  N     . PHE A 1 92  ? 399.717 355.605 333.037 1.00 116.24 ? 92  PHE B N     1 
ATOM   710   C  CA    . PHE A 1 92  ? 399.588 356.578 334.116 1.00 118.71 ? 92  PHE B CA    1 
ATOM   711   C  C     . PHE A 1 92  ? 400.680 356.366 335.153 1.00 120.53 ? 92  PHE B C     1 
ATOM   712   O  O     . PHE A 1 92  ? 401.317 355.310 335.208 1.00 123.21 ? 92  PHE B O     1 
ATOM   713   C  CB    . PHE A 1 92  ? 398.182 356.531 334.760 1.00 119.21 ? 92  PHE B CB    1 
ATOM   714   C  CG    . PHE A 1 92  ? 397.780 355.181 335.360 1.00 122.19 ? 92  PHE B CG    1 
ATOM   715   C  CD1   . PHE A 1 92  ? 398.113 354.895 336.678 1.00 119.40 ? 92  PHE B CD1   1 
ATOM   716   C  CD2   . PHE A 1 92  ? 397.139 354.190 334.623 1.00 122.53 ? 92  PHE B CD2   1 
ATOM   717   C  CE1   . PHE A 1 92  ? 397.780 353.686 337.248 1.00 122.22 ? 92  PHE B CE1   1 
ATOM   718   C  CE2   . PHE A 1 92  ? 396.807 352.985 335.195 1.00 125.08 ? 92  PHE B CE2   1 
ATOM   719   C  CZ    . PHE A 1 92  ? 397.132 352.731 336.508 1.00 129.12 ? 92  PHE B CZ    1 
ATOM   720   N  N     . GLY A 1 93  ? 400.889 357.404 335.968 1.00 110.09 ? 93  GLY B N     1 
ATOM   721   C  CA    . GLY A 1 93  ? 401.658 357.305 337.187 1.00 107.41 ? 93  GLY B CA    1 
ATOM   722   C  C     . GLY A 1 93  ? 400.746 357.294 338.406 1.00 112.82 ? 93  GLY B C     1 
ATOM   723   O  O     . GLY A 1 93  ? 399.544 357.531 338.318 1.00 115.48 ? 93  GLY B O     1 
ATOM   724   N  N     . GLN A 1 94  ? 401.349 357.014 339.560 1.00 130.24 ? 94  GLN B N     1 
ATOM   725   C  CA    . GLN A 1 94  ? 400.621 356.938 340.821 1.00 131.17 ? 94  GLN B CA    1 
ATOM   726   C  C     . GLN A 1 94  ? 400.499 358.280 341.537 1.00 127.61 ? 94  GLN B C     1 
ATOM   727   O  O     . GLN A 1 94  ? 399.857 358.335 342.592 1.00 131.02 ? 94  GLN B O     1 
ATOM   728   C  CB    . GLN A 1 94  ? 401.297 355.927 341.757 1.00 131.93 ? 94  GLN B CB    1 
ATOM   729   C  CG    . GLN A 1 94  ? 401.226 354.464 341.294 1.00 134.32 ? 94  GLN B CG    1 
ATOM   730   C  CD    . GLN A 1 94  ? 401.971 353.513 342.216 1.00 134.91 ? 94  GLN B CD    1 
ATOM   731   O  OE1   . GLN A 1 94  ? 402.900 353.913 342.919 1.00 134.75 ? 94  GLN B OE1   1 
ATOM   732   N  NE2   . GLN A 1 94  ? 401.558 352.250 342.227 1.00 125.65 ? 94  GLN B NE2   1 
ATOM   733   N  N     . SER A 1 95  ? 401.090 359.353 341.004 1.00 117.95 ? 95  SER B N     1 
ATOM   734   C  CA    . SER A 1 95  ? 401.071 360.663 341.643 1.00 119.71 ? 95  SER B CA    1 
ATOM   735   C  C     . SER A 1 95  ? 400.905 361.732 340.577 1.00 120.96 ? 95  SER B C     1 
ATOM   736   O  O     . SER A 1 95  ? 401.631 361.734 339.579 1.00 125.63 ? 95  SER B O     1 
ATOM   737   C  CB    . SER A 1 95  ? 402.360 360.909 342.434 1.00 123.46 ? 95  SER B CB    1 
ATOM   738   O  OG    . SER A 1 95  ? 402.558 359.899 343.406 1.00 130.11 ? 95  SER B OG    1 
ATOM   739   N  N     . GLY A 1 96  ? 399.955 362.637 340.794 1.00 109.69 ? 96  GLY B N     1 
ATOM   740   C  CA    . GLY A 1 96  ? 399.722 363.711 339.855 1.00 110.80 ? 96  GLY B CA    1 
ATOM   741   C  C     . GLY A 1 96  ? 400.746 364.820 339.982 1.00 107.34 ? 96  GLY B C     1 
ATOM   742   O  O     . GLY A 1 96  ? 401.572 364.842 340.893 1.00 101.17 ? 96  GLY B O     1 
ATOM   743   N  N     . ALA A 1 97  ? 400.676 365.756 339.038 1.00 106.74 ? 97  ALA B N     1 
ATOM   744   C  CA    . ALA A 1 97  ? 401.560 366.914 339.011 1.00 104.67 ? 97  ALA B CA    1 
ATOM   745   C  C     . ALA A 1 97  ? 401.019 368.104 339.794 1.00 106.25 ? 97  ALA B C     1 
ATOM   746   O  O     . ALA A 1 97  ? 401.679 369.146 339.831 1.00 108.14 ? 97  ALA B O     1 
ATOM   747   C  CB    . ALA A 1 97  ? 401.818 367.347 337.567 1.00 104.23 ? 97  ALA B CB    1 
ATOM   748   N  N     . GLY A 1 98  ? 399.850 367.983 340.422 1.00 111.01 ? 98  GLY B N     1 
ATOM   749   C  CA    . GLY A 1 98  ? 399.201 369.142 340.997 1.00 108.95 ? 98  GLY B CA    1 
ATOM   750   C  C     . GLY A 1 98  ? 398.845 370.129 339.907 1.00 113.58 ? 98  GLY B C     1 
ATOM   751   O  O     . GLY A 1 98  ? 397.939 369.881 339.105 1.00 120.80 ? 98  GLY B O     1 
ATOM   752   N  N     . ASN A 1 99  ? 399.553 371.259 339.875 1.00 98.31  ? 99  ASN B N     1 
ATOM   753   C  CA    . ASN A 1 99  ? 399.493 372.190 338.755 1.00 102.94 ? 99  ASN B CA    1 
ATOM   754   C  C     . ASN A 1 99  ? 400.880 372.733 338.438 1.00 99.19  ? 99  ASN B C     1 
ATOM   755   O  O     . ASN A 1 99  ? 401.019 373.875 337.987 1.00 103.01 ? 99  ASN B O     1 
ATOM   756   C  CB    . ASN A 1 99  ? 398.520 373.335 339.042 1.00 103.80 ? 99  ASN B CB    1 
ATOM   757   C  CG    . ASN A 1 99  ? 397.090 372.858 339.195 1.00 103.84 ? 99  ASN B CG    1 
ATOM   758   O  OD1   . ASN A 1 99  ? 396.490 372.991 340.260 1.00 105.26 ? 99  ASN B OD1   1 
ATOM   759   N  ND2   . ASN A 1 99  ? 396.539 372.289 338.130 1.00 101.28 ? 99  ASN B ND2   1 
ATOM   760   N  N     . ASN A 1 100 ? 401.911 371.920 338.656 1.00 91.64  ? 100 ASN B N     1 
ATOM   761   C  CA    . ASN A 1 100 ? 403.300 372.338 338.530 1.00 91.22  ? 100 ASN B CA    1 
ATOM   762   C  C     . ASN A 1 100 ? 403.833 371.883 337.177 1.00 90.90  ? 100 ASN B C     1 
ATOM   763   O  O     . ASN A 1 100 ? 403.943 370.677 336.916 1.00 100.91 ? 100 ASN B O     1 
ATOM   764   C  CB    . ASN A 1 100 ? 404.127 371.759 339.678 1.00 91.47  ? 100 ASN B CB    1 
ATOM   765   C  CG    . ASN A 1 100 ? 405.508 372.380 339.790 1.00 94.29  ? 100 ASN B CG    1 
ATOM   766   O  OD1   . ASN A 1 100 ? 406.031 372.958 338.840 1.00 97.26  ? 100 ASN B OD1   1 
ATOM   767   N  ND2   . ASN A 1 100 ? 406.107 372.260 340.968 1.00 96.49  ? 100 ASN B ND2   1 
ATOM   768   N  N     . TRP A 1 101 ? 404.164 372.856 336.324 1.00 90.52  ? 101 TRP B N     1 
ATOM   769   C  CA    . TRP A 1 101 ? 404.757 372.549 335.028 1.00 96.41  ? 101 TRP B CA    1 
ATOM   770   C  C     . TRP A 1 101 ? 406.085 371.828 335.202 1.00 102.12 ? 101 TRP B C     1 
ATOM   771   O  O     . TRP A 1 101 ? 406.415 370.926 334.427 1.00 104.05 ? 101 TRP B O     1 
ATOM   772   C  CB    . TRP A 1 101 ? 404.955 373.838 334.232 1.00 97.61  ? 101 TRP B CB    1 
ATOM   773   C  CG    . TRP A 1 101 ? 405.246 373.636 332.777 1.00 99.31  ? 101 TRP B CG    1 
ATOM   774   C  CD1   . TRP A 1 101 ? 404.344 373.663 331.759 1.00 106.13 ? 101 TRP B CD1   1 
ATOM   775   C  CD2   . TRP A 1 101 ? 406.523 373.393 332.174 1.00 94.63  ? 101 TRP B CD2   1 
ATOM   776   N  NE1   . TRP A 1 101 ? 404.973 373.449 330.559 1.00 106.99 ? 101 TRP B NE1   1 
ATOM   777   C  CE2   . TRP A 1 101 ? 406.313 373.279 330.787 1.00 104.04 ? 101 TRP B CE2   1 
ATOM   778   C  CE3   . TRP A 1 101 ? 407.821 373.255 332.671 1.00 90.78  ? 101 TRP B CE3   1 
ATOM   779   C  CZ2   . TRP A 1 101 ? 407.352 373.037 329.893 1.00 102.16 ? 101 TRP B CZ2   1 
ATOM   780   C  CZ3   . TRP A 1 101 ? 408.849 373.014 331.782 1.00 93.86  ? 101 TRP B CZ3   1 
ATOM   781   C  CH2   . TRP A 1 101 ? 408.609 372.906 330.408 1.00 98.25  ? 101 TRP B CH2   1 
ATOM   782   N  N     . ALA A 1 102 ? 406.855 372.214 336.221 1.00 99.24  ? 102 ALA B N     1 
ATOM   783   C  CA    . ALA A 1 102 ? 408.128 371.556 336.492 1.00 96.41  ? 102 ALA B CA    1 
ATOM   784   C  C     . ALA A 1 102 ? 407.928 370.088 336.843 1.00 100.63 ? 102 ALA B C     1 
ATOM   785   O  O     . ALA A 1 102 ? 408.644 369.217 336.333 1.00 99.91  ? 102 ALA B O     1 
ATOM   786   C  CB    . ALA A 1 102 ? 408.846 372.273 337.632 1.00 100.32 ? 102 ALA B CB    1 
ATOM   787   N  N     . LYS A 1 103 ? 406.961 369.800 337.715 1.00 108.71 ? 103 LYS B N     1 
ATOM   788   C  CA    . LYS A 1 103 ? 406.680 368.423 338.107 1.00 108.11 ? 103 LYS B CA    1 
ATOM   789   C  C     . LYS A 1 103 ? 406.207 367.608 336.911 1.00 102.64 ? 103 LYS B C     1 
ATOM   790   O  O     . LYS A 1 103 ? 406.644 366.471 336.702 1.00 101.33 ? 103 LYS B O     1 
ATOM   791   C  CB    . LYS A 1 103 ? 405.631 368.412 339.220 1.00 103.43 ? 103 LYS B CB    1 
ATOM   792   C  CG    . LYS A 1 103 ? 405.430 367.080 339.918 1.00 105.65 ? 103 LYS B CG    1 
ATOM   793   C  CD    . LYS A 1 103 ? 404.647 367.259 341.218 1.00 103.28 ? 103 LYS B CD    1 
ATOM   794   C  CE    . LYS A 1 103 ? 404.454 365.941 341.951 1.00 112.75 ? 103 LYS B CE    1 
ATOM   795   N  NZ    . LYS A 1 103 ? 405.740 365.359 342.422 1.00 112.40 ? 103 LYS B NZ    1 
ATOM   796   N  N     . GLY A 1 104 ? 405.311 368.184 336.107 1.00 114.38 ? 104 GLY B N     1 
ATOM   797   C  CA    . GLY A 1 104 ? 404.816 367.472 334.941 1.00 117.62 ? 104 GLY B CA    1 
ATOM   798   C  C     . GLY A 1 104 ? 405.879 367.225 333.889 1.00 115.53 ? 104 GLY B C     1 
ATOM   799   O  O     . GLY A 1 104 ? 405.875 366.181 333.232 1.00 116.15 ? 104 GLY B O     1 
ATOM   800   N  N     . HIS A 1 105 ? 406.804 368.170 333.719 1.00 107.28 ? 105 HIS B N     1 
ATOM   801   C  CA    . HIS A 1 105 ? 407.788 368.078 332.646 1.00 102.55 ? 105 HIS B CA    1 
ATOM   802   C  C     . HIS A 1 105 ? 408.966 367.200 333.050 1.00 98.98  ? 105 HIS B C     1 
ATOM   803   O  O     . HIS A 1 105 ? 409.287 366.220 332.370 1.00 100.23 ? 105 HIS B O     1 
ATOM   804   C  CB    . HIS A 1 105 ? 408.260 369.484 332.270 1.00 101.47 ? 105 HIS B CB    1 
ATOM   805   C  CG    . HIS A 1 105 ? 409.066 369.541 331.010 1.00 104.25 ? 105 HIS B CG    1 
ATOM   806   N  ND1   . HIS A 1 105 ? 408.494 369.730 329.770 1.00 107.21 ? 105 HIS B ND1   1 
ATOM   807   C  CD2   . HIS A 1 105 ? 410.400 369.457 330.800 1.00 100.24 ? 105 HIS B CD2   1 
ATOM   808   C  CE1   . HIS A 1 105 ? 409.441 369.748 328.850 1.00 99.50  ? 105 HIS B CE1   1 
ATOM   809   N  NE2   . HIS A 1 105 ? 410.607 369.585 329.448 1.00 100.64 ? 105 HIS B NE2   1 
ATOM   810   N  N     . TYR A 1 106 ? 409.623 367.537 334.163 1.00 101.66 ? 106 TYR B N     1 
ATOM   811   C  CA    . TYR A 1 106 ? 410.890 366.900 334.509 1.00 105.28 ? 106 TYR B CA    1 
ATOM   812   C  C     . TYR A 1 106 ? 410.699 365.633 335.338 1.00 107.52 ? 106 TYR B C     1 
ATOM   813   O  O     . TYR A 1 106 ? 411.058 364.537 334.897 1.00 115.40 ? 106 TYR B O     1 
ATOM   814   C  CB    . TYR A 1 106 ? 411.780 367.900 335.247 1.00 99.02  ? 106 TYR B CB    1 
ATOM   815   C  CG    . TYR A 1 106 ? 412.301 368.989 334.344 1.00 103.52 ? 106 TYR B CG    1 
ATOM   816   C  CD1   . TYR A 1 106 ? 413.459 368.801 333.603 1.00 106.04 ? 106 TYR B CD1   1 
ATOM   817   C  CD2   . TYR A 1 106 ? 411.626 370.192 334.209 1.00 105.21 ? 106 TYR B CD2   1 
ATOM   818   C  CE1   . TYR A 1 106 ? 413.940 369.786 332.766 1.00 104.46 ? 106 TYR B CE1   1 
ATOM   819   C  CE2   . TYR A 1 106 ? 412.100 371.183 333.374 1.00 104.77 ? 106 TYR B CE2   1 
ATOM   820   C  CZ    . TYR A 1 106 ? 413.255 370.975 332.655 1.00 101.12 ? 106 TYR B CZ    1 
ATOM   821   O  OH    . TYR A 1 106 ? 413.722 371.964 331.824 1.00 96.50  ? 106 TYR B OH    1 
ATOM   822   N  N     . THR A 1 107 ? 410.104 365.757 336.527 1.00 98.97  ? 107 THR B N     1 
ATOM   823   C  CA    . THR A 1 107 ? 410.173 364.671 337.502 1.00 101.88 ? 107 THR B CA    1 
ATOM   824   C  C     . THR A 1 107 ? 409.329 363.476 337.073 1.00 110.19 ? 107 THR B C     1 
ATOM   825   O  O     . THR A 1 107 ? 409.857 362.386 336.825 1.00 113.03 ? 107 THR B O     1 
ATOM   826   C  CB    . THR A 1 107 ? 409.727 365.171 338.875 1.00 108.13 ? 107 THR B CB    1 
ATOM   827   O  OG1   . THR A 1 107 ? 408.358 365.585 338.813 1.00 117.26 ? 107 THR B OG1   1 
ATOM   828   C  CG2   . THR A 1 107 ? 410.592 366.337 339.325 1.00 106.64 ? 107 THR B CG2   1 
ATOM   829   N  N     . GLU A 1 108 ? 408.012 363.662 336.966 1.00 114.40 ? 108 GLU B N     1 
ATOM   830   C  CA    . GLU A 1 108 ? 407.150 362.558 336.549 1.00 115.84 ? 108 GLU B CA    1 
ATOM   831   C  C     . GLU A 1 108 ? 407.282 362.287 335.056 1.00 119.35 ? 108 GLU B C     1 
ATOM   832   O  O     . GLU A 1 108 ? 407.037 361.158 334.604 1.00 125.91 ? 108 GLU B O     1 
ATOM   833   C  CB    . GLU A 1 108 ? 405.689 362.849 336.903 1.00 115.29 ? 108 GLU B CB    1 
ATOM   834   C  CG    . GLU A 1 108 ? 405.452 363.465 338.282 1.00 114.37 ? 108 GLU B CG    1 
ATOM   835   C  CD    . GLU A 1 108 ? 406.116 362.691 339.402 1.00 119.89 ? 108 GLU B CD    1 
ATOM   836   O  OE1   . GLU A 1 108 ? 406.298 361.464 339.260 1.00 122.95 ? 108 GLU B OE1   1 
ATOM   837   O  OE2   . GLU A 1 108 ? 406.461 363.313 340.428 1.00 123.80 ? 108 GLU B OE2   1 
ATOM   838   N  N     . GLY A 1 109 ? 407.645 363.311 334.280 1.00 108.01 ? 109 GLY B N     1 
ATOM   839   C  CA    . GLY A 1 109 ? 407.885 363.105 332.864 1.00 107.98 ? 109 GLY B CA    1 
ATOM   840   C  C     . GLY A 1 109 ? 409.014 362.130 332.605 1.00 113.71 ? 109 GLY B C     1 
ATOM   841   O  O     . GLY A 1 109 ? 408.878 361.217 331.790 1.00 120.52 ? 109 GLY B O     1 
ATOM   842   N  N     . ALA A 1 110 ? 410.128 362.279 333.329 1.00 117.84 ? 110 ALA B N     1 
ATOM   843   C  CA    . ALA A 1 110 ? 411.272 361.395 333.128 1.00 122.41 ? 110 ALA B CA    1 
ATOM   844   C  C     . ALA A 1 110 ? 410.951 359.941 333.449 1.00 125.57 ? 110 ALA B C     1 
ATOM   845   O  O     . ALA A 1 110 ? 411.622 359.044 332.926 1.00 128.20 ? 110 ALA B O     1 
ATOM   846   C  CB    . ALA A 1 110 ? 412.453 361.864 333.978 1.00 125.51 ? 110 ALA B CB    1 
ATOM   847   N  N     . GLU A 1 111 ? 409.940 359.686 334.283 1.00 122.15 ? 111 GLU B N     1 
ATOM   848   C  CA    . GLU A 1 111 ? 409.496 358.320 334.531 1.00 122.97 ? 111 GLU B CA    1 
ATOM   849   C  C     . GLU A 1 111 ? 408.555 357.834 333.433 1.00 124.72 ? 111 GLU B C     1 
ATOM   850   O  O     . GLU A 1 111 ? 408.791 356.782 332.828 1.00 127.68 ? 111 GLU B O     1 
ATOM   851   C  CB    . GLU A 1 111 ? 408.813 358.222 335.899 1.00 123.47 ? 111 GLU B CB    1 
ATOM   852   C  CG    . GLU A 1 111 ? 409.521 358.957 337.038 1.00 124.81 ? 111 GLU B CG    1 
ATOM   853   C  CD    . GLU A 1 111 ? 411.015 358.696 337.084 1.00 127.19 ? 111 GLU B CD    1 
ATOM   854   O  OE1   . GLU A 1 111 ? 411.428 357.545 336.835 1.00 128.21 ? 111 GLU B OE1   1 
ATOM   855   O  OE2   . GLU A 1 111 ? 411.775 359.643 337.377 1.00 126.81 ? 111 GLU B OE2   1 
ATOM   856   N  N     . LEU A 1 112 ? 407.488 358.589 333.150 1.00 119.52 ? 112 LEU B N     1 
ATOM   857   C  CA    . LEU A 1 112 ? 406.406 358.054 332.322 1.00 121.64 ? 112 LEU B CA    1 
ATOM   858   C  C     . LEU A 1 112 ? 406.648 358.175 330.819 1.00 123.17 ? 112 LEU B C     1 
ATOM   859   O  O     . LEU A 1 112 ? 406.026 357.415 330.051 1.00 125.29 ? 112 LEU B O     1 
ATOM   860   C  CB    . LEU A 1 112 ? 405.082 358.750 332.658 1.00 119.72 ? 112 LEU B CB    1 
ATOM   861   C  CG    . LEU A 1 112 ? 404.125 358.025 333.610 1.00 124.63 ? 112 LEU B CG    1 
ATOM   862   C  CD1   . LEU A 1 112 ? 403.332 356.990 332.831 1.00 124.25 ? 112 LEU B CD1   1 
ATOM   863   C  CD2   . LEU A 1 112 ? 404.819 357.401 334.829 1.00 123.34 ? 112 LEU B CD2   1 
ATOM   864   N  N     . VAL A 1 113 ? 407.534 359.083 330.388 1.00 113.53 ? 113 VAL B N     1 
ATOM   865   C  CA    . VAL A 1 113 ? 407.647 359.421 328.973 1.00 115.96 ? 113 VAL B CA    1 
ATOM   866   C  C     . VAL A 1 113 ? 408.132 358.226 328.168 1.00 118.78 ? 113 VAL B C     1 
ATOM   867   O  O     . VAL A 1 113 ? 407.717 358.032 327.022 1.00 120.34 ? 113 VAL B O     1 
ATOM   868   C  CB    . VAL A 1 113 ? 408.559 360.649 328.784 1.00 110.98 ? 113 VAL B CB    1 
ATOM   869   C  CG1   . VAL A 1 113 ? 410.020 360.337 329.141 1.00 113.30 ? 113 VAL B CG1   1 
ATOM   870   C  CG2   . VAL A 1 113 ? 408.448 361.180 327.367 1.00 109.93 ? 113 VAL B CG2   1 
ATOM   871   N  N     . ASP A 1 114 ? 409.003 357.404 328.756 1.00 131.49 ? 114 ASP B N     1 
ATOM   872   C  CA    . ASP A 1 114 ? 409.501 356.228 328.057 1.00 136.23 ? 114 ASP B CA    1 
ATOM   873   C  C     . ASP A 1 114 ? 408.364 355.264 327.741 1.00 138.47 ? 114 ASP B C     1 
ATOM   874   O  O     . ASP A 1 114 ? 408.234 354.796 326.602 1.00 142.02 ? 114 ASP B O     1 
ATOM   875   C  CB    . ASP A 1 114 ? 410.576 355.543 328.898 1.00 135.43 ? 114 ASP B CB    1 
ATOM   876   C  CG    . ASP A 1 114 ? 411.778 356.435 329.150 1.00 136.62 ? 114 ASP B CG    1 
ATOM   877   O  OD1   . ASP A 1 114 ? 411.888 357.491 328.491 1.00 137.41 ? 114 ASP B OD1   1 
ATOM   878   O  OD2   . ASP A 1 114 ? 412.610 356.085 330.013 1.00 136.92 ? 114 ASP B OD2   1 
ATOM   879   N  N     . SER A 1 115 ? 407.509 354.985 328.729 1.00 139.94 ? 115 SER B N     1 
ATOM   880   C  CA    . SER A 1 115 ? 406.405 354.057 328.509 1.00 142.19 ? 115 SER B CA    1 
ATOM   881   C  C     . SER A 1 115 ? 405.436 354.594 327.463 1.00 143.13 ? 115 SER B C     1 
ATOM   882   O  O     . SER A 1 115 ? 405.036 353.864 326.538 1.00 149.14 ? 115 SER B O     1 
ATOM   883   C  CB    . SER A 1 115 ? 405.679 353.781 329.823 1.00 143.87 ? 115 SER B CB    1 
ATOM   884   O  OG    . SER A 1 115 ? 404.645 352.825 329.646 1.00 150.37 ? 115 SER B OG    1 
ATOM   885   N  N     . VAL A 1 116 ? 405.070 355.879 327.566 1.00 121.70 ? 116 VAL B N     1 
ATOM   886   C  CA    . VAL A 1 116 ? 404.085 356.387 326.606 1.00 127.02 ? 116 VAL B CA    1 
ATOM   887   C  C     . VAL A 1 116 ? 404.700 356.469 325.210 1.00 127.40 ? 116 VAL B C     1 
ATOM   888   O  O     . VAL A 1 116 ? 403.995 356.312 324.208 1.00 128.84 ? 116 VAL B O     1 
ATOM   889   C  CB    . VAL A 1 116 ? 403.459 357.738 327.030 1.00 125.39 ? 116 VAL B CB    1 
ATOM   890   C  CG1   . VAL A 1 116 ? 404.465 358.754 327.466 1.00 123.97 ? 116 VAL B CG1   1 
ATOM   891   C  CG2   . VAL A 1 116 ? 402.575 358.312 325.920 1.00 122.33 ? 116 VAL B CG2   1 
ATOM   892   N  N     . LEU A 1 117 ? 406.019 356.678 325.109 1.00 122.02 ? 117 LEU B N     1 
ATOM   893   C  CA    . LEU A 1 117 ? 406.634 356.726 323.785 1.00 121.37 ? 117 LEU B CA    1 
ATOM   894   C  C     . LEU A 1 117 ? 406.760 355.347 323.150 1.00 121.57 ? 117 LEU B C     1 
ATOM   895   O  O     . LEU A 1 117 ? 406.621 355.232 321.931 1.00 119.07 ? 117 LEU B O     1 
ATOM   896   C  CB    . LEU A 1 117 ? 407.998 357.407 323.844 1.00 118.21 ? 117 LEU B CB    1 
ATOM   897   C  CG    . LEU A 1 117 ? 407.990 358.938 323.926 1.00 115.63 ? 117 LEU B CG    1 
ATOM   898   C  CD1   . LEU A 1 117 ? 409.400 359.421 324.175 1.00 117.95 ? 117 LEU B CD1   1 
ATOM   899   C  CD2   . LEU A 1 117 ? 407.413 359.604 322.667 1.00 115.26 ? 117 LEU B CD2   1 
ATOM   900   N  N     . ASP A 1 118 ? 407.018 354.291 323.930 1.00 144.44 ? 118 ASP B N     1 
ATOM   901   C  CA    . ASP A 1 118 ? 406.891 352.950 323.351 1.00 144.96 ? 118 ASP B CA    1 
ATOM   902   C  C     . ASP A 1 118 ? 405.463 352.658 322.909 1.00 144.27 ? 118 ASP B C     1 
ATOM   903   O  O     . ASP A 1 118 ? 405.256 352.004 321.879 1.00 146.35 ? 118 ASP B O     1 
ATOM   904   C  CB    . ASP A 1 118 ? 407.409 351.868 324.299 1.00 142.80 ? 118 ASP B CB    1 
ATOM   905   C  CG    . ASP A 1 118 ? 408.817 352.137 324.787 1.00 146.18 ? 118 ASP B CG    1 
ATOM   906   O  OD1   . ASP A 1 118 ? 409.266 353.298 324.749 1.00 146.41 ? 118 ASP B OD1   1 
ATOM   907   O  OD2   . ASP A 1 118 ? 409.481 351.167 325.212 1.00 148.51 ? 118 ASP B OD2   1 
ATOM   908   N  N     . VAL A 1 119 ? 404.463 353.142 323.647 1.00 126.35 ? 119 VAL B N     1 
ATOM   909   C  CA    . VAL A 1 119 ? 403.086 352.929 323.195 1.00 119.01 ? 119 VAL B CA    1 
ATOM   910   C  C     . VAL A 1 119 ? 402.829 353.678 321.882 1.00 120.06 ? 119 VAL B C     1 
ATOM   911   O  O     . VAL A 1 119 ? 402.235 353.131 320.935 1.00 125.18 ? 119 VAL B O     1 
ATOM   912   C  CB    . VAL A 1 119 ? 402.085 353.336 324.294 1.00 115.25 ? 119 VAL B CB    1 
ATOM   913   C  CG1   . VAL A 1 119 ? 400.662 353.258 323.784 1.00 115.39 ? 119 VAL B CG1   1 
ATOM   914   C  CG2   . VAL A 1 119 ? 402.214 352.436 325.515 1.00 120.41 ? 119 VAL B CG2   1 
ATOM   915   N  N     . VAL A 1 120 ? 403.285 354.931 321.804 1.00 116.38 ? 120 VAL B N     1 
ATOM   916   C  CA    . VAL A 1 120 ? 403.102 355.735 320.597 1.00 117.22 ? 120 VAL B CA    1 
ATOM   917   C  C     . VAL A 1 120 ? 403.844 355.103 319.429 1.00 120.58 ? 120 VAL B C     1 
ATOM   918   O  O     . VAL A 1 120 ? 403.359 355.109 318.293 1.00 122.46 ? 120 VAL B O     1 
ATOM   919   C  CB    . VAL A 1 120 ? 403.562 357.188 320.841 1.00 112.82 ? 120 VAL B CB    1 
ATOM   920   C  CG1   . VAL A 1 120 ? 403.677 357.970 319.524 1.00 111.16 ? 120 VAL B CG1   1 
ATOM   921   C  CG2   . VAL A 1 120 ? 402.602 357.913 321.771 1.00 116.35 ? 120 VAL B CG2   1 
ATOM   922   N  N     . ARG A 1 121 ? 405.032 354.557 319.684 1.00 132.59 ? 121 ARG B N     1 
ATOM   923   C  CA    . ARG A 1 121 ? 405.777 353.887 318.627 1.00 132.96 ? 121 ARG B CA    1 
ATOM   924   C  C     . ARG A 1 121 ? 405.065 352.625 318.157 1.00 133.77 ? 121 ARG B C     1 
ATOM   925   O  O     . ARG A 1 121 ? 405.062 352.326 316.955 1.00 132.99 ? 121 ARG B O     1 
ATOM   926   C  CB    . ARG A 1 121 ? 407.195 353.571 319.106 1.00 137.21 ? 121 ARG B CB    1 
ATOM   927   C  CG    . ARG A 1 121 ? 408.182 353.402 317.966 1.00 140.88 ? 121 ARG B CG    1 
ATOM   928   C  CD    . ARG A 1 121 ? 409.605 353.128 318.438 1.00 140.37 ? 121 ARG B CD    1 
ATOM   929   N  NE    . ARG A 1 121 ? 410.169 354.238 319.207 1.00 141.27 ? 121 ARG B NE    1 
ATOM   930   C  CZ    . ARG A 1 121 ? 410.222 354.338 320.533 1.00 141.53 ? 121 ARG B CZ    1 
ATOM   931   N  NH1   . ARG A 1 121 ? 409.730 353.404 321.332 1.00 142.33 ? 121 ARG B NH1   1 
ATOM   932   N  NH2   . ARG A 1 121 ? 410.791 355.411 321.075 1.00 139.50 ? 121 ARG B NH2   1 
ATOM   933   N  N     . LYS A 1 122 ? 404.456 351.870 319.086 1.00 131.90 ? 122 LYS B N     1 
ATOM   934   C  CA    . LYS A 1 122 ? 403.743 350.662 318.677 1.00 132.01 ? 122 LYS B CA    1 
ATOM   935   C  C     . LYS A 1 122 ? 402.574 351.024 317.772 1.00 130.41 ? 122 LYS B C     1 
ATOM   936   O  O     . LYS A 1 122 ? 402.293 350.325 316.791 1.00 131.00 ? 122 LYS B O     1 
ATOM   937   C  CB    . LYS A 1 122 ? 403.273 349.822 319.891 1.00 133.86 ? 122 LYS B CB    1 
ATOM   938   C  CG    . LYS A 1 122 ? 401.742 349.806 320.268 1.00 136.51 ? 122 LYS B CG    1 
ATOM   939   C  CD    . LYS A 1 122 ? 401.438 349.494 321.740 1.00 138.11 ? 122 LYS B CD    1 
ATOM   940   C  CE    . LYS A 1 122 ? 399.991 349.890 322.129 1.00 134.97 ? 122 LYS B CE    1 
ATOM   941   N  NZ    . LYS A 1 122 ? 399.750 349.893 323.596 1.00 134.46 ? 122 LYS B NZ    1 
ATOM   942   N  N     . GLU A 1 123 ? 401.891 352.128 318.082 1.00 128.33 ? 123 GLU B N     1 
ATOM   943   C  CA    . GLU A 1 123 ? 400.795 352.557 317.222 1.00 131.27 ? 123 GLU B CA    1 
ATOM   944   C  C     . GLU A 1 123 ? 401.317 353.105 315.899 1.00 129.72 ? 123 GLU B C     1 
ATOM   945   O  O     . GLU A 1 123 ? 400.719 352.863 314.846 1.00 130.82 ? 123 GLU B O     1 
ATOM   946   C  CB    . GLU A 1 123 ? 399.927 353.593 317.941 1.00 130.18 ? 123 GLU B CB    1 
ATOM   947   C  CG    . GLU A 1 123 ? 399.131 353.040 319.125 1.00 129.62 ? 123 GLU B CG    1 
ATOM   948   C  CD    . GLU A 1 123 ? 398.048 352.054 318.710 1.00 131.37 ? 123 GLU B CD    1 
ATOM   949   O  OE1   . GLU A 1 123 ? 397.697 352.017 317.513 1.00 134.21 ? 123 GLU B OE1   1 
ATOM   950   O  OE2   . GLU A 1 123 ? 397.557 351.307 319.582 1.00 127.76 ? 123 GLU B OE2   1 
ATOM   951   N  N     . ALA A 1 124 ? 402.443 353.823 315.930 1.00 126.11 ? 124 ALA B N     1 
ATOM   952   C  CA    . ALA A 1 124 ? 402.961 354.458 314.723 1.00 125.75 ? 124 ALA B CA    1 
ATOM   953   C  C     . ALA A 1 124 ? 403.435 353.432 313.702 1.00 129.30 ? 124 ALA B C     1 
ATOM   954   O  O     . ALA A 1 124 ? 403.202 353.600 312.499 1.00 128.44 ? 124 ALA B O     1 
ATOM   955   C  CB    . ALA A 1 124 ? 404.097 355.412 315.083 1.00 120.92 ? 124 ALA B CB    1 
ATOM   956   N  N     . GLU A 1 125 ? 404.114 352.371 314.151 1.00 144.18 ? 125 GLU B N     1 
ATOM   957   C  CA    . GLU A 1 125 ? 404.571 351.354 313.205 1.00 143.94 ? 125 GLU B CA    1 
ATOM   958   C  C     . GLU A 1 125 ? 403.414 350.619 312.540 1.00 140.43 ? 125 GLU B C     1 
ATOM   959   O  O     . GLU A 1 125 ? 403.578 350.119 311.422 1.00 142.12 ? 125 GLU B O     1 
ATOM   960   C  CB    . GLU A 1 125 ? 405.487 350.327 313.886 1.00 143.90 ? 125 GLU B CB    1 
ATOM   961   C  CG    . GLU A 1 125 ? 406.745 350.853 314.609 1.00 143.57 ? 125 GLU B CG    1 
ATOM   962   C  CD    . GLU A 1 125 ? 407.256 352.193 314.105 1.00 144.43 ? 125 GLU B CD    1 
ATOM   963   O  OE1   . GLU A 1 125 ? 407.469 352.333 312.883 1.00 144.79 ? 125 GLU B OE1   1 
ATOM   964   O  OE2   . GLU A 1 125 ? 407.437 353.110 314.933 1.00 145.99 ? 125 GLU B OE2   1 
ATOM   965   N  N     . SER A 1 126 ? 402.252 350.540 313.191 1.00 127.86 ? 126 SER B N     1 
ATOM   966   C  CA    . SER A 1 126 ? 401.101 349.895 312.573 1.00 127.86 ? 126 SER B CA    1 
ATOM   967   C  C     . SER A 1 126 ? 400.535 350.692 311.402 1.00 129.89 ? 126 SER B C     1 
ATOM   968   O  O     . SER A 1 126 ? 399.818 350.120 310.574 1.00 132.14 ? 126 SER B O     1 
ATOM   969   C  CB    . SER A 1 126 ? 400.005 349.670 313.615 1.00 131.66 ? 126 SER B CB    1 
ATOM   970   O  OG    . SER A 1 126 ? 398.876 349.039 313.035 1.00 131.52 ? 126 SER B OG    1 
ATOM   971   N  N     . CYS A 1 127 ? 400.828 351.988 311.312 1.00 140.54 ? 127 CYS B N     1 
ATOM   972   C  CA    . CYS A 1 127 ? 400.243 352.814 310.264 1.00 140.59 ? 127 CYS B CA    1 
ATOM   973   C  C     . CYS A 1 127 ? 400.798 352.443 308.895 1.00 142.82 ? 127 CYS B C     1 
ATOM   974   O  O     . CYS A 1 127 ? 402.001 352.224 308.731 1.00 143.22 ? 127 CYS B O     1 
ATOM   975   C  CB    . CYS A 1 127 ? 400.511 354.291 310.540 1.00 139.05 ? 127 CYS B CB    1 
ATOM   976   S  SG    . CYS A 1 127 ? 399.746 354.909 312.046 1.00 146.77 ? 127 CYS B SG    1 
ATOM   977   N  N     . ASP A 1 128 ? 399.905 352.375 307.906 1.00 150.83 ? 128 ASP B N     1 
ATOM   978   C  CA    . ASP A 1 128 ? 400.344 352.177 306.529 1.00 149.79 ? 128 ASP B CA    1 
ATOM   979   C  C     . ASP A 1 128 ? 401.055 353.434 306.036 1.00 147.27 ? 128 ASP B C     1 
ATOM   980   O  O     . ASP A 1 128 ? 402.132 353.357 305.434 1.00 147.43 ? 128 ASP B O     1 
ATOM   981   C  CB    . ASP A 1 128 ? 399.130 351.814 305.651 1.00 149.68 ? 128 ASP B CB    1 
ATOM   982   C  CG    . ASP A 1 128 ? 399.287 352.186 304.168 1.00 150.73 ? 128 ASP B CG    1 
ATOM   983   O  OD1   . ASP A 1 128 ? 398.243 352.445 303.535 1.00 152.77 ? 128 ASP B OD1   1 
ATOM   984   O  OD2   . ASP A 1 128 ? 400.388 352.071 303.581 1.00 149.76 ? 128 ASP B OD2   1 
ATOM   985   N  N     . CYS A 1 129 ? 400.459 354.601 306.284 1.00 134.33 ? 129 CYS B N     1 
ATOM   986   C  CA    . CYS A 1 129 ? 401.081 355.887 305.969 1.00 131.28 ? 129 CYS B CA    1 
ATOM   987   C  C     . CYS A 1 129 ? 400.626 356.874 307.039 1.00 132.26 ? 129 CYS B C     1 
ATOM   988   O  O     . CYS A 1 129 ? 399.474 357.318 307.031 1.00 135.41 ? 129 CYS B O     1 
ATOM   989   C  CB    . CYS A 1 129 ? 400.708 356.369 304.575 1.00 136.45 ? 129 CYS B CB    1 
ATOM   990   S  SG    . CYS A 1 129 ? 401.402 357.987 304.176 1.00 144.85 ? 129 CYS B SG    1 
ATOM   991   N  N     . LEU A 1 130 ? 401.535 357.213 307.945 1.00 108.72 ? 130 LEU B N     1 
ATOM   992   C  CA    . LEU A 1 130 ? 401.204 358.048 309.090 1.00 105.92 ? 130 LEU B CA    1 
ATOM   993   C  C     . LEU A 1 130 ? 401.219 359.517 308.686 1.00 105.22 ? 130 LEU B C     1 
ATOM   994   O  O     . LEU A 1 130 ? 402.262 360.043 308.287 1.00 104.54 ? 130 LEU B O     1 
ATOM   995   C  CB    . LEU A 1 130 ? 402.193 357.781 310.225 1.00 103.90 ? 130 LEU B CB    1 
ATOM   996   C  CG    . LEU A 1 130 ? 402.140 358.641 311.491 1.00 105.14 ? 130 LEU B CG    1 
ATOM   997   C  CD1   . LEU A 1 130 ? 400.765 358.612 312.142 1.00 108.15 ? 130 LEU B CD1   1 
ATOM   998   C  CD2   . LEU A 1 130 ? 403.197 358.173 312.476 1.00 111.58 ? 130 LEU B CD2   1 
ATOM   999   N  N     . GLN A 1 131 ? 400.058 360.165 308.768 1.00 113.70 ? 131 GLN B N     1 
ATOM   1000  C  CA    . GLN A 1 131 ? 399.966 361.618 308.716 1.00 107.38 ? 131 GLN B CA    1 
ATOM   1001  C  C     . GLN A 1 131 ? 400.209 362.135 310.134 1.00 112.75 ? 131 GLN B C     1 
ATOM   1002  O  O     . GLN A 1 131 ? 400.689 361.407 311.006 1.00 115.23 ? 131 GLN B O     1 
ATOM   1003  C  CB    . GLN A 1 131 ? 398.622 362.051 308.126 1.00 108.33 ? 131 GLN B CB    1 
ATOM   1004  C  CG    . GLN A 1 131 ? 398.611 363.458 307.474 1.00 106.78 ? 131 GLN B CG    1 
ATOM   1005  C  CD    . GLN A 1 131 ? 397.797 363.541 306.192 1.00 112.34 ? 131 GLN B CD    1 
ATOM   1006  O  OE1   . GLN A 1 131 ? 398.222 364.168 305.222 1.00 109.69 ? 131 GLN B OE1   1 
ATOM   1007  N  NE2   . GLN A 1 131 ? 396.609 362.953 306.196 1.00 118.11 ? 131 GLN B NE2   1 
ATOM   1008  N  N     . GLY A 1 132 ? 399.894 363.394 310.396 1.00 115.93 ? 132 GLY B N     1 
ATOM   1009  C  CA    . GLY A 1 132 ? 400.342 364.012 311.621 1.00 116.59 ? 132 GLY B CA    1 
ATOM   1010  C  C     . GLY A 1 132 ? 399.614 363.539 312.865 1.00 114.13 ? 132 GLY B C     1 
ATOM   1011  O  O     . GLY A 1 132 ? 398.604 362.835 312.825 1.00 115.31 ? 132 GLY B O     1 
ATOM   1012  N  N     . PHE A 1 133 ? 400.166 363.955 314.004 1.00 102.83 ? 133 PHE B N     1 
ATOM   1013  C  CA    . PHE A 1 133 ? 399.650 363.635 315.325 1.00 94.31  ? 133 PHE B CA    1 
ATOM   1014  C  C     . PHE A 1 133 ? 398.621 364.681 315.748 1.00 94.25  ? 133 PHE B C     1 
ATOM   1015  O  O     . PHE A 1 133 ? 398.447 365.716 315.101 1.00 104.47 ? 133 PHE B O     1 
ATOM   1016  C  CB    . PHE A 1 133 ? 400.786 363.591 316.351 1.00 91.37  ? 133 PHE B CB    1 
ATOM   1017  C  CG    . PHE A 1 133 ? 401.794 362.507 316.110 1.00 89.21  ? 133 PHE B CG    1 
ATOM   1018  C  CD1   . PHE A 1 133 ? 402.837 362.699 315.223 1.00 94.19  ? 133 PHE B CD1   1 
ATOM   1019  C  CD2   . PHE A 1 133 ? 401.714 361.306 316.790 1.00 95.35  ? 133 PHE B CD2   1 
ATOM   1020  C  CE1   . PHE A 1 133 ? 403.770 361.710 315.005 1.00 98.36  ? 133 PHE B CE1   1 
ATOM   1021  C  CE2   . PHE A 1 133 ? 402.647 360.312 316.576 1.00 98.06  ? 133 PHE B CE2   1 
ATOM   1022  C  CZ    . PHE A 1 133 ? 403.676 360.515 315.683 1.00 98.43  ? 133 PHE B CZ    1 
ATOM   1023  N  N     . GLN A 1 134 ? 397.931 364.395 316.850 1.00 85.65  ? 134 GLN B N     1 
ATOM   1024  C  CA    . GLN A 1 134 ? 397.064 365.363 317.503 1.00 88.58  ? 134 GLN B CA    1 
ATOM   1025  C  C     . GLN A 1 134 ? 397.251 365.202 319.004 1.00 95.55  ? 134 GLN B C     1 
ATOM   1026  O  O     . GLN A 1 134 ? 397.557 364.108 319.486 1.00 101.47 ? 134 GLN B O     1 
ATOM   1027  C  CB    . GLN A 1 134 ? 395.590 365.185 317.028 1.00 89.75  ? 134 GLN B CB    1 
ATOM   1028  C  CG    . GLN A 1 134 ? 394.419 365.372 318.048 1.00 103.79 ? 134 GLN B CG    1 
ATOM   1029  C  CD    . GLN A 1 134 ? 393.102 364.760 317.583 1.00 107.68 ? 134 GLN B CD    1 
ATOM   1030  O  OE1   . GLN A 1 134 ? 393.053 363.974 316.635 1.00 106.34 ? 134 GLN B OE1   1 
ATOM   1031  N  NE2   . GLN A 1 134 ? 392.019 365.127 318.260 1.00 106.64 ? 134 GLN B NE2   1 
ATOM   1032  N  N     . LEU A 1 135 ? 397.073 366.304 319.736 1.00 93.24  ? 135 LEU B N     1 
ATOM   1033  C  CA    . LEU A 1 135 ? 397.132 366.302 321.194 1.00 90.72  ? 135 LEU B CA    1 
ATOM   1034  C  C     . LEU A 1 135 ? 396.043 367.204 321.748 1.00 91.03  ? 135 LEU B C     1 
ATOM   1035  O  O     . LEU A 1 135 ? 395.775 368.273 321.191 1.00 100.44 ? 135 LEU B O     1 
ATOM   1036  C  CB    . LEU A 1 135 ? 398.501 366.764 321.715 1.00 95.05  ? 135 LEU B CB    1 
ATOM   1037  C  CG    . LEU A 1 135 ? 398.686 366.834 323.247 1.00 102.17 ? 135 LEU B CG    1 
ATOM   1038  C  CD1   . LEU A 1 135 ? 398.504 365.470 323.887 1.00 104.72 ? 135 LEU B CD1   1 
ATOM   1039  C  CD2   . LEU A 1 135 ? 400.041 367.400 323.622 1.00 98.93  ? 135 LEU B CD2   1 
ATOM   1040  N  N     . THR A 1 136 ? 395.434 366.765 322.847 1.00 81.45  ? 136 THR B N     1 
ATOM   1041  C  CA    . THR A 1 136 ? 394.498 367.559 323.631 1.00 87.85  ? 136 THR B CA    1 
ATOM   1042  C  C     . THR A 1 136 ? 395.101 367.787 325.007 1.00 94.22  ? 136 THR B C     1 
ATOM   1043  O  O     . THR A 1 136 ? 395.487 366.830 325.685 1.00 103.96 ? 136 THR B O     1 
ATOM   1044  C  CB    . THR A 1 136 ? 393.149 366.854 323.761 1.00 99.55  ? 136 THR B CB    1 
ATOM   1045  O  OG1   . THR A 1 136 ? 393.344 365.545 324.308 1.00 106.42 ? 136 THR B OG1   1 
ATOM   1046  C  CG2   . THR A 1 136 ? 392.494 366.730 322.411 1.00 95.50  ? 136 THR B CG2   1 
ATOM   1047  N  N     . HIS A 1 137 ? 395.178 369.047 325.417 1.00 94.93  ? 137 HIS B N     1 
ATOM   1048  C  CA    . HIS A 1 137 ? 395.826 369.397 326.673 1.00 94.00  ? 137 HIS B CA    1 
ATOM   1049  C  C     . HIS A 1 137 ? 395.404 370.806 327.056 1.00 97.66  ? 137 HIS B C     1 
ATOM   1050  O  O     . HIS A 1 137 ? 394.836 371.545 326.250 1.00 100.65 ? 137 HIS B O     1 
ATOM   1051  C  CB    . HIS A 1 137 ? 397.354 369.287 326.573 1.00 89.44  ? 137 HIS B CB    1 
ATOM   1052  C  CG    . HIS A 1 137 ? 397.979 370.260 325.618 1.00 88.89  ? 137 HIS B CG    1 
ATOM   1053  N  ND1   . HIS A 1 137 ? 399.021 371.085 325.981 1.00 97.60  ? 137 HIS B ND1   1 
ATOM   1054  C  CD2   . HIS A 1 137 ? 397.726 370.526 324.315 1.00 93.24  ? 137 HIS B CD2   1 
ATOM   1055  C  CE1   . HIS A 1 137 ? 399.374 371.827 324.946 1.00 100.95 ? 137 HIS B CE1   1 
ATOM   1056  N  NE2   . HIS A 1 137 ? 398.603 371.508 323.923 1.00 97.99  ? 137 HIS B NE2   1 
ATOM   1057  N  N     . SER A 1 138 ? 395.675 371.156 328.311 1.00 105.07 ? 138 SER B N     1 
ATOM   1058  C  CA    . SER A 1 138 ? 395.390 372.472 328.867 1.00 103.66 ? 138 SER B CA    1 
ATOM   1059  C  C     . SER A 1 138 ? 396.701 373.153 329.227 1.00 110.34 ? 138 SER B C     1 
ATOM   1060  O  O     . SER A 1 138 ? 397.541 372.564 329.916 1.00 115.66 ? 138 SER B O     1 
ATOM   1061  C  CB    . SER A 1 138 ? 394.501 372.358 330.104 1.00 107.97 ? 138 SER B CB    1 
ATOM   1062  O  OG    . SER A 1 138 ? 394.702 373.458 330.971 1.00 115.99 ? 138 SER B OG    1 
ATOM   1063  N  N     . LEU A 1 139 ? 396.875 374.392 328.763 1.00 101.03 ? 139 LEU B N     1 
ATOM   1064  C  CA    . LEU A 1 139 ? 398.098 375.120 329.078 1.00 101.70 ? 139 LEU B CA    1 
ATOM   1065  C  C     . LEU A 1 139 ? 398.136 375.550 330.538 1.00 107.94 ? 139 LEU B C     1 
ATOM   1066  O  O     . LEU A 1 139 ? 399.222 375.669 331.118 1.00 113.80 ? 139 LEU B O     1 
ATOM   1067  C  CB    . LEU A 1 139 ? 398.239 376.340 328.168 1.00 98.24  ? 139 LEU B CB    1 
ATOM   1068  C  CG    . LEU A 1 139 ? 398.031 376.130 326.669 1.00 97.40  ? 139 LEU B CG    1 
ATOM   1069  C  CD1   . LEU A 1 139 ? 398.285 377.426 325.923 1.00 99.49  ? 139 LEU B CD1   1 
ATOM   1070  C  CD2   . LEU A 1 139 ? 398.915 375.019 326.125 1.00 100.88 ? 139 LEU B CD2   1 
ATOM   1071  N  N     . GLY A 1 140 ? 396.974 375.782 331.152 1.00 109.62 ? 140 GLY B N     1 
ATOM   1072  C  CA    . GLY A 1 140 ? 396.945 376.192 332.544 1.00 107.20 ? 140 GLY B CA    1 
ATOM   1073  C  C     . GLY A 1 140 ? 397.272 375.094 333.531 1.00 105.01 ? 140 GLY B C     1 
ATOM   1074  O  O     . GLY A 1 140 ? 397.712 375.392 334.645 1.00 106.28 ? 140 GLY B O     1 
ATOM   1075  N  N     . GLY A 1 141 ? 397.074 373.832 333.150 1.00 119.48 ? 141 GLY B N     1 
ATOM   1076  C  CA    . GLY A 1 141 ? 397.341 372.732 334.049 1.00 121.97 ? 141 GLY B CA    1 
ATOM   1077  C  C     . GLY A 1 141 ? 398.813 372.379 334.124 1.00 119.31 ? 141 GLY B C     1 
ATOM   1078  O  O     . GLY A 1 141 ? 399.630 372.795 333.304 1.00 122.92 ? 141 GLY B O     1 
ATOM   1079  N  N     . GLY A 1 142 ? 399.146 371.590 335.142 1.00 102.21 ? 142 GLY B N     1 
ATOM   1080  C  CA    . GLY A 1 142 ? 400.498 371.101 335.315 1.00 98.28  ? 142 GLY B CA    1 
ATOM   1081  C  C     . GLY A 1 142 ? 400.768 369.865 334.486 1.00 100.70 ? 142 GLY B C     1 
ATOM   1082  O  O     . GLY A 1 142 ? 401.693 369.851 333.666 1.00 106.36 ? 142 GLY B O     1 
ATOM   1083  N  N     . THR A 1 143 ? 399.955 368.825 334.703 1.00 105.43 ? 143 THR B N     1 
ATOM   1084  C  CA    . THR A 1 143 ? 400.129 367.561 333.992 1.00 106.60 ? 143 THR B CA    1 
ATOM   1085  C  C     . THR A 1 143 ? 400.012 367.754 332.490 1.00 105.42 ? 143 THR B C     1 
ATOM   1086  O  O     . THR A 1 143 ? 400.894 367.335 331.733 1.00 107.40 ? 143 THR B O     1 
ATOM   1087  C  CB    . THR A 1 143 ? 399.091 366.541 334.466 1.00 109.62 ? 143 THR B CB    1 
ATOM   1088  O  OG1   . THR A 1 143 ? 399.310 366.225 335.846 1.00 118.53 ? 143 THR B OG1   1 
ATOM   1089  C  CG2   . THR A 1 143 ? 399.155 365.264 333.633 1.00 103.51 ? 143 THR B CG2   1 
ATOM   1090  N  N     . GLY A 1 144 ? 398.927 368.395 332.048 1.00 100.33 ? 144 GLY B N     1 
ATOM   1091  C  CA    . GLY A 1 144 ? 398.698 368.559 330.622 1.00 97.21  ? 144 GLY B CA    1 
ATOM   1092  C  C     . GLY A 1 144 ? 399.799 369.351 329.948 1.00 100.85 ? 144 GLY B C     1 
ATOM   1093  O  O     . GLY A 1 144 ? 400.372 368.906 328.955 1.00 102.79 ? 144 GLY B O     1 
ATOM   1094  N  N     . SER A 1 145 ? 400.166 370.492 330.536 1.00 110.19 ? 145 SER B N     1 
ATOM   1095  C  CA    . SER A 1 145 ? 401.201 371.336 329.947 1.00 106.89 ? 145 SER B CA    1 
ATOM   1096  C  C     . SER A 1 145 ? 402.550 370.627 329.909 1.00 111.93 ? 145 SER B C     1 
ATOM   1097  O  O     . SER A 1 145 ? 403.173 370.522 328.846 1.00 112.14 ? 145 SER B O     1 
ATOM   1098  C  CB    . SER A 1 145 ? 401.308 372.646 330.725 1.00 105.28 ? 145 SER B CB    1 
ATOM   1099  O  OG    . SER A 1 145 ? 400.039 373.247 330.892 1.00 117.20 ? 145 SER B OG    1 
ATOM   1100  N  N     . GLY A 1 146 ? 403.007 370.104 331.049 1.00 111.19 ? 146 GLY B N     1 
ATOM   1101  C  CA    . GLY A 1 146 ? 404.311 369.475 331.103 1.00 102.71 ? 146 GLY B CA    1 
ATOM   1102  C  C     . GLY A 1 146 ? 404.430 368.238 330.237 1.00 104.22 ? 146 GLY B C     1 
ATOM   1103  O  O     . GLY A 1 146 ? 405.362 368.131 329.426 1.00 108.00 ? 146 GLY B O     1 
ATOM   1104  N  N     . MET A 1 147 ? 403.484 367.303 330.377 1.00 102.07 ? 147 MET B N     1 
ATOM   1105  C  CA    . MET A 1 147 ? 403.557 366.079 329.594 1.00 103.64 ? 147 MET B CA    1 
ATOM   1106  C  C     . MET A 1 147 ? 403.359 366.368 328.115 1.00 109.54 ? 147 MET B C     1 
ATOM   1107  O  O     . MET A 1 147 ? 404.019 365.755 327.271 1.00 116.39 ? 147 MET B O     1 
ATOM   1108  C  CB    . MET A 1 147 ? 402.518 365.070 330.081 1.00 111.67 ? 147 MET B CB    1 
ATOM   1109  C  CG    . MET A 1 147 ? 402.860 364.415 331.422 1.00 113.87 ? 147 MET B CG    1 
ATOM   1110  S  SD    . MET A 1 147 ? 404.340 363.368 331.547 1.00 118.78 ? 147 MET B SD    1 
ATOM   1111  C  CE    . MET A 1 147 ? 404.605 362.746 329.886 1.00 109.31 ? 147 MET B CE    1 
ATOM   1112  N  N     . GLY A 1 148 ? 402.465 367.304 327.776 1.00 102.36 ? 148 GLY B N     1 
ATOM   1113  C  CA    . GLY A 1 148 ? 402.265 367.639 326.380 1.00 100.98 ? 148 GLY B CA    1 
ATOM   1114  C  C     . GLY A 1 148 ? 403.510 368.224 325.751 1.00 104.76 ? 148 GLY B C     1 
ATOM   1115  O  O     . GLY A 1 148 ? 403.891 367.845 324.648 1.00 107.57 ? 148 GLY B O     1 
ATOM   1116  N  N     . THR A 1 149 ? 404.183 369.130 326.462 1.00 100.17 ? 149 THR B N     1 
ATOM   1117  C  CA    . THR A 1 149 ? 405.421 369.696 325.936 1.00 98.30  ? 149 THR B CA    1 
ATOM   1118  C  C     . THR A 1 149 ? 406.495 368.630 325.772 1.00 100.16 ? 149 THR B C     1 
ATOM   1119  O  O     . THR A 1 149 ? 407.211 368.611 324.762 1.00 105.65 ? 149 THR B O     1 
ATOM   1120  C  CB    . THR A 1 149 ? 405.918 370.801 326.858 1.00 106.80 ? 149 THR B CB    1 
ATOM   1121  O  OG1   . THR A 1 149 ? 405.956 370.314 328.205 1.00 115.34 ? 149 THR B OG1   1 
ATOM   1122  C  CG2   . THR A 1 149 ? 405.013 372.008 326.779 1.00 105.99 ? 149 THR B CG2   1 
ATOM   1123  N  N     . LEU A 1 150 ? 406.614 367.729 326.749 1.00 92.01  ? 150 LEU B N     1 
ATOM   1124  C  CA    . LEU A 1 150 ? 407.638 366.693 326.675 1.00 94.82  ? 150 LEU B CA    1 
ATOM   1125  C  C     . LEU A 1 150 ? 407.372 365.739 325.511 1.00 104.12 ? 150 LEU B C     1 
ATOM   1126  O  O     . LEU A 1 150 ? 408.285 365.411 324.737 1.00 108.58 ? 150 LEU B O     1 
ATOM   1127  C  CB    . LEU A 1 150 ? 407.691 365.948 328.008 1.00 90.98  ? 150 LEU B CB    1 
ATOM   1128  C  CG    . LEU A 1 150 ? 408.823 364.951 328.239 1.00 95.69  ? 150 LEU B CG    1 
ATOM   1129  C  CD1   . LEU A 1 150 ? 410.168 365.657 328.315 1.00 98.52  ? 150 LEU B CD1   1 
ATOM   1130  C  CD2   . LEU A 1 150 ? 408.556 364.168 329.510 1.00 100.24 ? 150 LEU B CD2   1 
ATOM   1131  N  N     . LEU A 1 151 ? 406.118 365.295 325.360 1.00 99.37  ? 151 LEU B N     1 
ATOM   1132  C  CA    . LEU A 1 151 ? 405.759 364.455 324.220 1.00 93.72  ? 151 LEU B CA    1 
ATOM   1133  C  C     . LEU A 1 151 ? 405.939 365.186 322.899 1.00 100.04 ? 151 LEU B C     1 
ATOM   1134  O  O     . LEU A 1 151 ? 406.381 364.581 321.926 1.00 108.40 ? 151 LEU B O     1 
ATOM   1135  C  CB    . LEU A 1 151 ? 404.313 363.945 324.331 1.00 98.18  ? 151 LEU B CB    1 
ATOM   1136  C  CG    . LEU A 1 151 ? 403.780 362.985 325.419 1.00 101.51 ? 151 LEU B CG    1 
ATOM   1137  C  CD1   . LEU A 1 151 ? 402.270 362.785 325.339 1.00 103.15 ? 151 LEU B CD1   1 
ATOM   1138  C  CD2   . LEU A 1 151 ? 404.477 361.634 325.436 1.00 99.32  ? 151 LEU B CD2   1 
ATOM   1139  N  N     . ILE A 1 152 ? 405.593 366.472 322.837 1.00 104.72 ? 152 ILE B N     1 
ATOM   1140  C  CA    . ILE A 1 152 ? 405.763 367.241 321.602 1.00 107.77 ? 152 ILE B CA    1 
ATOM   1141  C  C     . ILE A 1 152 ? 407.232 367.277 321.203 1.00 108.82 ? 152 ILE B C     1 
ATOM   1142  O  O     . ILE A 1 152 ? 407.582 366.998 320.049 1.00 114.41 ? 152 ILE B O     1 
ATOM   1143  C  CB    . ILE A 1 152 ? 405.140 368.649 321.773 1.00 107.71 ? 152 ILE B CB    1 
ATOM   1144  C  CG1   . ILE A 1 152 ? 403.721 368.715 321.178 1.00 108.50 ? 152 ILE B CG1   1 
ATOM   1145  C  CG2   . ILE A 1 152 ? 405.929 369.765 321.067 1.00 113.52 ? 152 ILE B CG2   1 
ATOM   1146  C  CD1   . ILE A 1 152 ? 402.730 367.647 321.580 1.00 107.48 ? 152 ILE B CD1   1 
ATOM   1147  N  N     . SER A 1 153 ? 408.114 367.561 322.163 1.00 104.35 ? 153 SER B N     1 
ATOM   1148  C  CA    . SER A 1 153 ? 409.541 367.627 321.862 1.00 106.27 ? 153 SER B CA    1 
ATOM   1149  C  C     . SER A 1 153 ? 410.079 366.273 321.412 1.00 111.50 ? 153 SER B C     1 
ATOM   1150  O  O     . SER A 1 153 ? 410.756 366.170 320.381 1.00 115.95 ? 153 SER B O     1 
ATOM   1151  C  CB    . SER A 1 153 ? 410.307 368.122 323.087 1.00 107.02 ? 153 SER B CB    1 
ATOM   1152  O  OG    . SER A 1 153 ? 411.702 368.102 322.850 1.00 110.74 ? 153 SER B OG    1 
ATOM   1153  N  N     . LYS A 1 154 ? 409.759 365.211 322.153 1.00 104.00 ? 154 LYS B N     1 
ATOM   1154  C  CA    . LYS A 1 154 ? 410.353 363.918 321.832 1.00 98.42  ? 154 LYS B CA    1 
ATOM   1155  C  C     . LYS A 1 154 ? 409.727 363.295 320.586 1.00 101.83 ? 154 LYS B C     1 
ATOM   1156  O  O     . LYS A 1 154 ? 410.412 362.586 319.838 1.00 107.79 ? 154 LYS B O     1 
ATOM   1157  C  CB    . LYS A 1 154 ? 410.239 362.996 323.044 1.00 101.35 ? 154 LYS B CB    1 
ATOM   1158  C  CG    . LYS A 1 154 ? 411.205 363.394 324.160 1.00 105.49 ? 154 LYS B CG    1 
ATOM   1159  C  CD    . LYS A 1 154 ? 411.253 362.387 325.291 1.00 110.76 ? 154 LYS B CD    1 
ATOM   1160  C  CE    . LYS A 1 154 ? 412.161 361.209 324.976 1.00 110.41 ? 154 LYS B CE    1 
ATOM   1161  N  NZ    . LYS A 1 154 ? 413.601 361.575 325.056 1.00 110.37 ? 154 LYS B NZ    1 
ATOM   1162  N  N     . ILE A 1 155 ? 408.449 363.570 320.318 1.00 97.87  ? 155 ILE B N     1 
ATOM   1163  C  CA    . ILE A 1 155 ? 407.815 363.043 319.117 1.00 94.70  ? 155 ILE B CA    1 
ATOM   1164  C  C     . ILE A 1 155 ? 408.302 363.826 317.904 1.00 100.68 ? 155 ILE B C     1 
ATOM   1165  O  O     . ILE A 1 155 ? 408.368 363.276 316.803 1.00 108.15 ? 155 ILE B O     1 
ATOM   1166  C  CB    . ILE A 1 155 ? 406.273 363.064 319.276 1.00 93.28  ? 155 ILE B CB    1 
ATOM   1167  C  CG1   . ILE A 1 155 ? 405.838 362.074 320.375 1.00 100.93 ? 155 ILE B CG1   1 
ATOM   1168  C  CG2   . ILE A 1 155 ? 405.493 362.648 317.982 1.00 100.25 ? 155 ILE B CG2   1 
ATOM   1169  C  CD1   . ILE A 1 155 ? 404.418 362.278 320.857 1.00 98.14  ? 155 ILE B CD1   1 
ATOM   1170  N  N     . ARG A 1 156 ? 408.647 365.111 318.066 1.00 107.78 ? 156 ARG B N     1 
ATOM   1171  C  CA    . ARG A 1 156 ? 409.284 365.830 316.965 1.00 105.91 ? 156 ARG B CA    1 
ATOM   1172  C  C     . ARG A 1 156 ? 410.697 365.325 316.727 1.00 105.19 ? 156 ARG B C     1 
ATOM   1173  O  O     . ARG A 1 156 ? 411.178 365.325 315.588 1.00 109.77 ? 156 ARG B O     1 
ATOM   1174  C  CB    . ARG A 1 156 ? 409.306 367.334 317.238 1.00 105.63 ? 156 ARG B CB    1 
ATOM   1175  C  CG    . ARG A 1 156 ? 407.991 368.065 317.008 1.00 108.65 ? 156 ARG B CG    1 
ATOM   1176  C  CD    . ARG A 1 156 ? 407.592 368.188 315.533 1.00 110.78 ? 156 ARG B CD    1 
ATOM   1177  N  NE    . ARG A 1 156 ? 408.233 369.328 314.889 1.00 111.31 ? 156 ARG B NE    1 
ATOM   1178  C  CZ    . ARG A 1 156 ? 407.904 369.823 313.701 1.00 112.02 ? 156 ARG B CZ    1 
ATOM   1179  N  NH1   . ARG A 1 156 ? 406.916 369.313 312.978 1.00 112.43 ? 156 ARG B NH1   1 
ATOM   1180  N  NH2   . ARG A 1 156 ? 408.582 370.863 313.225 1.00 114.94 ? 156 ARG B NH2   1 
ATOM   1181  N  N     . GLU A 1 157 ? 411.393 364.930 317.793 1.00 117.20 ? 157 GLU B N     1 
ATOM   1182  C  CA    . GLU A 1 157 ? 412.700 364.303 317.626 1.00 123.09 ? 157 GLU B CA    1 
ATOM   1183  C  C     . GLU A 1 157 ? 412.570 363.017 316.814 1.00 123.19 ? 157 GLU B C     1 
ATOM   1184  O  O     . GLU A 1 157 ? 413.247 362.839 315.797 1.00 121.83 ? 157 GLU B O     1 
ATOM   1185  C  CB    . GLU A 1 157 ? 413.321 364.041 319.005 1.00 125.38 ? 157 GLU B CB    1 
ATOM   1186  C  CG    . GLU A 1 157 ? 414.512 363.068 319.098 1.00 127.15 ? 157 GLU B CG    1 
ATOM   1187  C  CD    . GLU A 1 157 ? 415.664 363.403 318.162 1.00 127.71 ? 157 GLU B CD    1 
ATOM   1188  O  OE1   . GLU A 1 157 ? 415.602 363.080 316.962 1.00 121.61 ? 157 GLU B OE1   1 
ATOM   1189  O  OE2   . GLU A 1 157 ? 416.652 363.994 318.644 1.00 130.25 ? 157 GLU B OE2   1 
ATOM   1190  N  N     . GLU A 1 158 ? 411.647 362.137 317.209 1.00 118.26 ? 158 GLU B N     1 
ATOM   1191  C  CA    . GLU A 1 158 ? 411.602 360.816 316.585 1.00 117.10 ? 158 GLU B CA    1 
ATOM   1192  C  C     . GLU A 1 158 ? 410.978 360.894 315.189 1.00 114.76 ? 158 GLU B C     1 
ATOM   1193  O  O     . GLU A 1 158 ? 411.430 360.207 314.266 1.00 113.85 ? 158 GLU B O     1 
ATOM   1194  C  CB    . GLU A 1 158 ? 410.828 359.846 317.485 1.00 119.86 ? 158 GLU B CB    1 
ATOM   1195  C  CG    . GLU A 1 158 ? 411.312 358.376 317.475 1.00 122.65 ? 158 GLU B CG    1 
ATOM   1196  C  CD    . GLU A 1 158 ? 410.838 357.531 316.306 1.00 126.01 ? 158 GLU B CD    1 
ATOM   1197  O  OE1   . GLU A 1 158 ? 411.131 356.317 316.306 1.00 125.30 ? 158 GLU B OE1   1 
ATOM   1198  O  OE2   . GLU A 1 158 ? 410.211 358.060 315.376 1.00 125.75 ? 158 GLU B OE2   1 
ATOM   1199  N  N     . TYR A 1 159 ? 409.959 361.743 315.014 1.00 108.46 ? 159 TYR B N     1 
ATOM   1200  C  CA    . TYR A 1 159 ? 409.226 361.924 313.755 1.00 109.06 ? 159 TYR B CA    1 
ATOM   1201  C  C     . TYR A 1 159 ? 409.299 363.397 313.346 1.00 114.54 ? 159 TYR B C     1 
ATOM   1202  O  O     . TYR A 1 159 ? 408.313 364.138 313.441 1.00 114.37 ? 159 TYR B O     1 
ATOM   1203  C  CB    . TYR A 1 159 ? 407.766 361.469 313.883 1.00 111.24 ? 159 TYR B CB    1 
ATOM   1204  C  CG    . TYR A 1 159 ? 407.495 360.207 314.672 1.00 111.46 ? 159 TYR B CG    1 
ATOM   1205  C  CD1   . TYR A 1 159 ? 407.572 358.957 314.073 1.00 110.30 ? 159 TYR B CD1   1 
ATOM   1206  C  CD2   . TYR A 1 159 ? 407.169 360.267 316.014 1.00 114.30 ? 159 TYR B CD2   1 
ATOM   1207  C  CE1   . TYR A 1 159 ? 407.296 357.803 314.789 1.00 108.56 ? 159 TYR B CE1   1 
ATOM   1208  C  CE2   . TYR A 1 159 ? 406.910 359.124 316.741 1.00 115.71 ? 159 TYR B CE2   1 
ATOM   1209  C  CZ    . TYR A 1 159 ? 406.982 357.893 316.128 1.00 113.60 ? 159 TYR B CZ    1 
ATOM   1210  O  OH    . TYR A 1 159 ? 406.726 356.751 316.852 1.00 118.72 ? 159 TYR B OH    1 
ATOM   1211  N  N     . PRO A 1 160 ? 410.464 363.859 312.883 1.00 114.63 ? 160 PRO B N     1 
ATOM   1212  C  CA    . PRO A 1 160 ? 410.566 365.273 312.488 1.00 109.81 ? 160 PRO B CA    1 
ATOM   1213  C  C     . PRO A 1 160 ? 409.763 365.618 311.245 1.00 111.72 ? 160 PRO B C     1 
ATOM   1214  O  O     . PRO A 1 160 ? 409.314 366.763 311.112 1.00 108.09 ? 160 PRO B O     1 
ATOM   1215  C  CB    . PRO A 1 160 ? 412.071 365.463 312.261 1.00 110.93 ? 160 PRO B CB    1 
ATOM   1216  C  CG    . PRO A 1 160 ? 412.564 364.112 311.899 1.00 111.89 ? 160 PRO B CG    1 
ATOM   1217  C  CD    . PRO A 1 160 ? 411.731 363.139 312.674 1.00 113.43 ? 160 PRO B CD    1 
ATOM   1218  N  N     . ASP A 1 161 ? 409.571 364.666 310.330 1.00 125.73 ? 161 ASP B N     1 
ATOM   1219  C  CA    . ASP A 1 161 ? 408.899 364.967 309.070 1.00 124.44 ? 161 ASP B CA    1 
ATOM   1220  C  C     . ASP A 1 161 ? 407.398 365.160 309.244 1.00 122.36 ? 161 ASP B C     1 
ATOM   1221  O  O     . ASP A 1 161 ? 406.782 365.918 308.487 1.00 124.85 ? 161 ASP B O     1 
ATOM   1222  C  CB    . ASP A 1 161 ? 409.161 363.848 308.062 1.00 127.26 ? 161 ASP B CB    1 
ATOM   1223  C  CG    . ASP A 1 161 ? 408.522 364.118 306.714 1.00 129.41 ? 161 ASP B CG    1 
ATOM   1224  O  OD1   . ASP A 1 161 ? 408.757 365.208 306.152 1.00 127.61 ? 161 ASP B OD1   1 
ATOM   1225  O  OD2   . ASP A 1 161 ? 407.783 363.242 306.219 1.00 129.45 ? 161 ASP B OD2   1 
ATOM   1226  N  N     . ARG A 1 162 ? 406.794 364.489 310.219 1.00 109.70 ? 162 ARG B N     1 
ATOM   1227  C  CA    . ARG A 1 162 ? 405.344 364.411 310.287 1.00 108.07 ? 162 ARG B CA    1 
ATOM   1228  C  C     . ARG A 1 162 ? 404.732 365.726 310.757 1.00 113.15 ? 162 ARG B C     1 
ATOM   1229  O  O     . ARG A 1 162 ? 405.335 366.490 311.515 1.00 116.63 ? 162 ARG B O     1 
ATOM   1230  C  CB    . ARG A 1 162 ? 404.913 363.283 311.229 1.00 105.97 ? 162 ARG B CB    1 
ATOM   1231  C  CG    . ARG A 1 162 ? 405.428 361.877 310.870 1.00 111.78 ? 162 ARG B CG    1 
ATOM   1232  C  CD    . ARG A 1 162 ? 404.541 361.165 309.857 1.00 115.17 ? 162 ARG B CD    1 
ATOM   1233  N  NE    . ARG A 1 162 ? 404.628 361.732 308.515 1.00 118.04 ? 162 ARG B NE    1 
ATOM   1234  C  CZ    . ARG A 1 162 ? 405.656 361.597 307.684 1.00 118.63 ? 162 ARG B CZ    1 
ATOM   1235  N  NH1   . ARG A 1 162 ? 406.732 360.893 308.007 1.00 120.81 ? 162 ARG B NH1   1 
ATOM   1236  N  NH2   . ARG A 1 162 ? 405.601 362.179 306.490 1.00 115.30 ? 162 ARG B NH2   1 
ATOM   1237  N  N     . ILE A 1 163 ? 403.507 365.980 310.287 1.00 111.14 ? 163 ILE B N     1 
ATOM   1238  C  CA    . ILE A 1 163 ? 402.684 367.056 310.829 1.00 109.17 ? 163 ILE B CA    1 
ATOM   1239  C  C     . ILE A 1 163 ? 402.398 366.752 312.305 1.00 108.69 ? 163 ILE B C     1 
ATOM   1240  O  O     . ILE A 1 163 ? 402.548 365.618 312.769 1.00 117.80 ? 163 ILE B O     1 
ATOM   1241  C  CB    . ILE A 1 163 ? 401.407 367.173 309.970 1.00 112.67 ? 163 ILE B CB    1 
ATOM   1242  C  CG1   . ILE A 1 163 ? 401.735 367.835 308.623 1.00 118.73 ? 163 ILE B CG1   1 
ATOM   1243  C  CG2   . ILE A 1 163 ? 400.251 367.932 310.637 1.00 108.71 ? 163 ILE B CG2   1 
ATOM   1244  C  CD1   . ILE A 1 163 ? 401.882 369.358 308.670 1.00 116.78 ? 163 ILE B CD1   1 
ATOM   1245  N  N     . MET A 1 164 ? 402.077 367.792 313.073 1.00 109.44 ? 164 MET B N     1 
ATOM   1246  C  CA    . MET A 1 164 ? 401.814 367.592 314.495 1.00 108.63 ? 164 MET B CA    1 
ATOM   1247  C  C     . MET A 1 164 ? 400.908 368.711 314.990 1.00 108.32 ? 164 MET B C     1 
ATOM   1248  O  O     . MET A 1 164 ? 401.358 369.853 315.131 1.00 115.12 ? 164 MET B O     1 
ATOM   1249  C  CB    . MET A 1 164 ? 403.132 367.541 315.254 1.00 107.14 ? 164 MET B CB    1 
ATOM   1250  C  CG    . MET A 1 164 ? 403.028 367.778 316.763 1.00 108.70 ? 164 MET B CG    1 
ATOM   1251  S  SD    . MET A 1 164 ? 404.373 367.208 317.849 1.00 121.79 ? 164 MET B SD    1 
ATOM   1252  C  CE    . MET A 1 164 ? 405.143 365.814 317.035 1.00 114.96 ? 164 MET B CE    1 
ATOM   1253  N  N     . ASN A 1 165 ? 399.649 368.373 315.268 1.00 106.31 ? 165 ASN B N     1 
ATOM   1254  C  CA    . ASN A 1 165 ? 398.636 369.321 315.711 1.00 102.59 ? 165 ASN B CA    1 
ATOM   1255  C  C     . ASN A 1 165 ? 398.477 369.245 317.224 1.00 105.21 ? 165 ASN B C     1 
ATOM   1256  O  O     . ASN A 1 165 ? 398.823 368.248 317.860 1.00 116.64 ? 165 ASN B O     1 
ATOM   1257  C  CB    . ASN A 1 165 ? 397.276 369.047 315.049 1.00 106.90 ? 165 ASN B CB    1 
ATOM   1258  C  CG    . ASN A 1 165 ? 397.190 369.480 313.569 1.00 109.95 ? 165 ASN B CG    1 
ATOM   1259  O  OD1   . ASN A 1 165 ? 396.080 369.659 313.069 1.00 114.64 ? 165 ASN B OD1   1 
ATOM   1260  N  ND2   . ASN A 1 165 ? 398.318 369.609 312.861 1.00 112.32 ? 165 ASN B ND2   1 
ATOM   1261  N  N     . THR A 1 166 ? 397.964 370.332 317.798 1.00 92.48  ? 166 THR B N     1 
ATOM   1262  C  CA    . THR A 1 166 ? 397.578 370.379 319.202 1.00 93.62  ? 166 THR B CA    1 
ATOM   1263  C  C     . THR A 1 166 ? 396.292 371.181 319.316 1.00 95.74  ? 166 THR B C     1 
ATOM   1264  O  O     . THR A 1 166 ? 396.011 372.051 318.491 1.00 96.54  ? 166 THR B O     1 
ATOM   1265  C  CB    . THR A 1 166 ? 398.655 371.018 320.094 1.00 98.31  ? 166 THR B CB    1 
ATOM   1266  O  OG1   . THR A 1 166 ? 398.721 372.424 319.832 1.00 107.47 ? 166 THR B OG1   1 
ATOM   1267  C  CG2   . THR A 1 166 ? 400.023 370.389 319.857 1.00 100.07 ? 166 THR B CG2   1 
ATOM   1268  N  N     . PHE A 1 167 ? 395.509 370.874 320.349 1.00 99.21  ? 167 PHE B N     1 
ATOM   1269  C  CA    . PHE A 1 167 ? 394.272 371.590 320.658 1.00 92.63  ? 167 PHE B CA    1 
ATOM   1270  C  C     . PHE A 1 167 ? 394.346 372.014 322.119 1.00 96.27  ? 167 PHE B C     1 
ATOM   1271  O  O     . PHE A 1 167 ? 394.078 371.215 323.020 1.00 101.30 ? 167 PHE B O     1 
ATOM   1272  C  CB    . PHE A 1 167 ? 393.055 370.724 320.391 1.00 88.60  ? 167 PHE B CB    1 
ATOM   1273  C  CG    . PHE A 1 167 ? 392.766 370.517 318.937 1.00 104.12 ? 167 PHE B CG    1 
ATOM   1274  C  CD1   . PHE A 1 167 ? 393.454 369.561 318.211 1.00 101.73 ? 167 PHE B CD1   1 
ATOM   1275  C  CD2   . PHE A 1 167 ? 391.787 371.257 318.301 1.00 110.76 ? 167 PHE B CD2   1 
ATOM   1276  C  CE1   . PHE A 1 167 ? 393.181 369.359 316.875 1.00 100.82 ? 167 PHE B CE1   1 
ATOM   1277  C  CE2   . PHE A 1 167 ? 391.509 371.061 316.966 1.00 104.29 ? 167 PHE B CE2   1 
ATOM   1278  C  CZ    . PHE A 1 167 ? 392.206 370.109 316.252 1.00 104.24 ? 167 PHE B CZ    1 
ATOM   1279  N  N     . SER A 1 168 ? 394.694 373.277 322.338 1.00 95.44  ? 168 SER B N     1 
ATOM   1280  C  CA    . SER A 1 168 ? 395.020 373.800 323.656 1.00 100.62 ? 168 SER B CA    1 
ATOM   1281  C  C     . SER A 1 168 ? 393.869 374.639 324.190 1.00 100.14 ? 168 SER B C     1 
ATOM   1282  O  O     . SER A 1 168 ? 393.403 375.562 323.515 1.00 100.70 ? 168 SER B O     1 
ATOM   1283  C  CB    . SER A 1 168 ? 396.295 374.637 323.587 1.00 104.06 ? 168 SER B CB    1 
ATOM   1284  O  OG    . SER A 1 168 ? 397.405 373.835 323.223 1.00 95.86  ? 168 SER B OG    1 
ATOM   1285  N  N     . VAL A 1 169 ? 393.417 374.315 325.400 1.00 92.49  ? 169 VAL B N     1 
ATOM   1286  C  CA    . VAL A 1 169 ? 392.435 375.133 326.115 1.00 93.59  ? 169 VAL B CA    1 
ATOM   1287  C  C     . VAL A 1 169 ? 393.242 376.206 326.837 1.00 96.56  ? 169 VAL B C     1 
ATOM   1288  O  O     . VAL A 1 169 ? 393.722 376.019 327.955 1.00 98.18  ? 169 VAL B O     1 
ATOM   1289  C  CB    . VAL A 1 169 ? 391.575 374.303 327.062 1.00 99.37  ? 169 VAL B CB    1 
ATOM   1290  C  CG1   . VAL A 1 169 ? 390.655 375.209 327.887 1.00 104.56 ? 169 VAL B CG1   1 
ATOM   1291  C  CG2   . VAL A 1 169 ? 390.771 373.278 326.262 1.00 100.05 ? 169 VAL B CG2   1 
ATOM   1292  N  N     . VAL A 1 170 ? 393.391 377.347 326.177 1.00 100.50 ? 170 VAL B N     1 
ATOM   1293  C  CA    . VAL A 1 170 ? 394.279 378.412 326.630 1.00 103.81 ? 170 VAL B CA    1 
ATOM   1294  C  C     . VAL A 1 170 ? 393.619 379.077 327.837 1.00 105.55 ? 170 VAL B C     1 
ATOM   1295  O  O     . VAL A 1 170 ? 392.387 379.016 327.953 1.00 103.73 ? 170 VAL B O     1 
ATOM   1296  C  CB    . VAL A 1 170 ? 394.553 379.401 325.484 1.00 96.55  ? 170 VAL B CB    1 
ATOM   1297  C  CG1   . VAL A 1 170 ? 395.554 380.479 325.882 1.00 103.03 ? 170 VAL B CG1   1 
ATOM   1298  C  CG2   . VAL A 1 170 ? 395.053 378.640 324.258 1.00 100.48 ? 170 VAL B CG2   1 
ATOM   1299  N  N     . PRO A 1 171 ? 394.364 379.685 328.770 1.00 109.27 ? 171 PRO B N     1 
ATOM   1300  C  CA    . PRO A 1 171 ? 393.711 380.455 329.840 1.00 108.04 ? 171 PRO B CA    1 
ATOM   1301  C  C     . PRO A 1 171 ? 392.872 381.607 329.306 1.00 113.41 ? 171 PRO B C     1 
ATOM   1302  O  O     . PRO A 1 171 ? 392.909 381.967 328.127 1.00 117.06 ? 171 PRO B O     1 
ATOM   1303  C  CB    . PRO A 1 171 ? 394.879 380.974 330.689 1.00 105.58 ? 171 PRO B CB    1 
ATOM   1304  C  CG    . PRO A 1 171 ? 396.127 380.508 330.024 1.00 103.83 ? 171 PRO B CG    1 
ATOM   1305  C  CD    . PRO A 1 171 ? 395.759 379.383 329.136 1.00 106.23 ? 171 PRO B CD    1 
ATOM   1306  N  N     . SER A 1 172 ? 392.118 382.203 330.225 1.00 117.40 ? 172 SER B N     1 
ATOM   1307  C  CA    . SER A 1 172 ? 391.064 383.168 329.964 1.00 114.98 ? 172 SER B CA    1 
ATOM   1308  C  C     . SER A 1 172 ? 391.336 384.480 330.696 1.00 118.51 ? 172 SER B C     1 
ATOM   1309  O  O     . SER A 1 172 ? 392.095 384.500 331.672 1.00 122.79 ? 172 SER B O     1 
ATOM   1310  C  CB    . SER A 1 172 ? 389.716 382.595 330.416 1.00 110.07 ? 172 SER B CB    1 
ATOM   1311  O  OG    . SER A 1 172 ? 388.679 383.518 330.184 1.00 110.86 ? 172 SER B OG    1 
ATOM   1312  N  N     . PRO A 1 173 ? 390.741 385.622 330.243 1.00 109.12 ? 173 PRO B N     1 
ATOM   1313  C  CA    . PRO A 1 173 ? 390.953 386.877 330.981 1.00 111.56 ? 173 PRO B CA    1 
ATOM   1314  C  C     . PRO A 1 173 ? 390.407 386.874 332.402 1.00 109.06 ? 173 PRO B C     1 
ATOM   1315  O  O     . PRO A 1 173 ? 391.150 387.165 333.345 1.00 105.41 ? 173 PRO B O     1 
ATOM   1316  C  CB    . PRO A 1 173 ? 390.233 387.920 330.113 1.00 107.41 ? 173 PRO B CB    1 
ATOM   1317  C  CG    . PRO A 1 173 ? 390.236 387.347 328.769 1.00 109.41 ? 173 PRO B CG    1 
ATOM   1318  C  CD    . PRO A 1 173 ? 390.039 385.886 328.970 1.00 100.36 ? 173 PRO B CD    1 
ATOM   1319  N  N     . LYS A 1 174 ? 389.127 386.544 332.574 1.00 106.43 ? 174 LYS B N     1 
ATOM   1320  C  CA    . LYS A 1 174 ? 388.442 386.706 333.852 1.00 107.14 ? 174 LYS B CA    1 
ATOM   1321  C  C     . LYS A 1 174 ? 388.441 385.444 334.701 1.00 107.65 ? 174 LYS B C     1 
ATOM   1322  O  O     . LYS A 1 174 ? 388.837 385.491 335.869 1.00 104.99 ? 174 LYS B O     1 
ATOM   1323  C  CB    . LYS A 1 174 ? 386.996 387.149 333.614 1.00 103.26 ? 174 LYS B CB    1 
ATOM   1324  N  N     . VAL A 1 175 ? 388.008 384.321 334.143 1.00 123.23 ? 175 VAL B N     1 
ATOM   1325  C  CA    . VAL A 1 175 ? 387.944 383.060 334.875 1.00 124.25 ? 175 VAL B CA    1 
ATOM   1326  C  C     . VAL A 1 175 ? 389.333 382.439 334.879 1.00 125.28 ? 175 VAL B C     1 
ATOM   1327  O  O     . VAL A 1 175 ? 390.023 382.434 333.854 1.00 126.22 ? 175 VAL B O     1 
ATOM   1328  C  CB    . VAL A 1 175 ? 386.908 382.095 334.257 1.00 127.73 ? 175 VAL B CB    1 
ATOM   1329  C  CG1   . VAL A 1 175 ? 385.487 382.667 334.366 1.00 125.27 ? 175 VAL B CG1   1 
ATOM   1330  C  CG2   . VAL A 1 175 ? 387.264 381.678 332.810 1.00 123.89 ? 175 VAL B CG2   1 
ATOM   1331  N  N     . SER A 1 176 ? 389.754 381.935 336.036 1.00 119.96 ? 176 SER B N     1 
ATOM   1332  C  CA    . SER A 1 176 ? 391.032 381.240 336.147 1.00 121.53 ? 176 SER B CA    1 
ATOM   1333  C  C     . SER A 1 176 ? 390.898 380.171 337.217 1.00 119.32 ? 176 SER B C     1 
ATOM   1334  O  O     . SER A 1 176 ? 390.682 380.493 338.389 1.00 123.99 ? 176 SER B O     1 
ATOM   1335  C  CB    . SER A 1 176 ? 392.162 382.212 336.486 1.00 120.17 ? 176 SER B CB    1 
ATOM   1336  O  OG    . SER A 1 176 ? 391.865 382.937 337.665 1.00 117.58 ? 176 SER B OG    1 
ATOM   1337  N  N     . ASP A 1 177 ? 391.029 378.911 336.811 1.00 124.53 ? 177 ASP B N     1 
ATOM   1338  C  CA    . ASP A 1 177 ? 390.900 377.774 337.711 1.00 129.03 ? 177 ASP B CA    1 
ATOM   1339  C  C     . ASP A 1 177 ? 392.223 377.370 338.355 1.00 131.86 ? 177 ASP B C     1 
ATOM   1340  O  O     . ASP A 1 177 ? 392.294 376.299 338.965 1.00 134.21 ? 177 ASP B O     1 
ATOM   1341  C  CB    . ASP A 1 177 ? 390.310 376.579 336.957 1.00 133.27 ? 177 ASP B CB    1 
ATOM   1342  C  CG    . ASP A 1 177 ? 389.161 376.972 336.049 1.00 134.54 ? 177 ASP B CG    1 
ATOM   1343  O  OD1   . ASP A 1 177 ? 388.192 377.586 336.543 1.00 135.29 ? 177 ASP B OD1   1 
ATOM   1344  O  OD2   . ASP A 1 177 ? 389.227 376.672 334.839 1.00 133.76 ? 177 ASP B OD2   1 
ATOM   1345  N  N     . THR A 1 178 ? 393.266 378.193 338.238 1.00 113.75 ? 178 THR B N     1 
ATOM   1346  C  CA    . THR A 1 178 ? 394.568 377.859 338.797 1.00 111.77 ? 178 THR B CA    1 
ATOM   1347  C  C     . THR A 1 178 ? 395.389 379.136 338.881 1.00 109.71 ? 178 THR B C     1 
ATOM   1348  O  O     . THR A 1 178 ? 395.459 379.890 337.907 1.00 115.97 ? 178 THR B O     1 
ATOM   1349  C  CB    . THR A 1 178 ? 395.276 376.804 337.937 1.00 116.50 ? 178 THR B CB    1 
ATOM   1350  O  OG1   . THR A 1 178 ? 394.607 375.545 338.075 1.00 121.90 ? 178 THR B OG1   1 
ATOM   1351  C  CG2   . THR A 1 178 ? 396.729 376.638 338.353 1.00 117.15 ? 178 THR B CG2   1 
ATOM   1352  N  N     . VAL A 1 179 ? 395.960 379.415 340.058 1.00 100.06 ? 179 VAL B N     1 
ATOM   1353  C  CA    . VAL A 1 179 ? 396.697 380.697 340.282 1.00 101.11 ? 179 VAL B CA    1 
ATOM   1354  C  C     . VAL A 1 179 ? 397.996 380.733 339.470 1.00 105.30 ? 179 VAL B C     1 
ATOM   1355  O  O     . VAL A 1 179 ? 398.351 381.828 339.002 1.00 107.73 ? 179 VAL B O     1 
ATOM   1356  C  CB    . VAL A 1 179 ? 396.974 380.925 341.780 1.00 100.84 ? 179 VAL B CB    1 
ATOM   1357  C  CG1   . VAL A 1 179 ? 397.828 382.162 342.010 1.00 106.06 ? 179 VAL B CG1   1 
ATOM   1358  C  CG2   . VAL A 1 179 ? 395.691 381.002 342.592 1.00 105.60 ? 179 VAL B CG2   1 
ATOM   1359  N  N     . VAL A 1 180 ? 398.669 379.595 339.298 1.00 96.51  ? 180 VAL B N     1 
ATOM   1360  C  CA    . VAL A 1 180 ? 399.988 379.588 338.599 1.00 91.60  ? 180 VAL B CA    1 
ATOM   1361  C  C     . VAL A 1 180 ? 399.771 379.454 337.087 1.00 95.27  ? 180 VAL B C     1 
ATOM   1362  O  O     . VAL A 1 180 ? 400.754 379.173 336.378 1.00 102.25 ? 180 VAL B O     1 
ATOM   1363  C  CB    . VAL A 1 180 ? 400.894 378.470 339.146 1.00 90.64  ? 180 VAL B CB    1 
ATOM   1364  C  CG1   . VAL A 1 180 ? 401.242 378.697 340.607 1.00 90.54  ? 180 VAL B CG1   1 
ATOM   1365  C  CG2   . VAL A 1 180 ? 400.276 377.096 338.950 1.00 95.70  ? 180 VAL B CG2   1 
ATOM   1366  N  N     . GLU A 1 181 ? 398.539 379.656 336.615 1.00 106.79 ? 181 GLU B N     1 
ATOM   1367  C  CA    . GLU A 1 181 ? 398.225 379.525 335.166 1.00 104.98 ? 181 GLU B CA    1 
ATOM   1368  C  C     . GLU A 1 181 ? 399.234 380.317 334.325 1.00 108.87 ? 181 GLU B C     1 
ATOM   1369  O  O     . GLU A 1 181 ? 399.759 379.721 333.367 1.00 118.08 ? 181 GLU B O     1 
ATOM   1370  C  CB    . GLU A 1 181 ? 396.787 379.953 334.870 1.00 111.81 ? 181 GLU B CB    1 
ATOM   1371  C  CG    . GLU A 1 181 ? 395.750 379.027 335.477 1.00 117.32 ? 181 GLU B CG    1 
ATOM   1372  C  CD    . GLU A 1 181 ? 394.308 379.456 335.268 1.00 123.51 ? 181 GLU B CD    1 
ATOM   1373  O  OE1   . GLU A 1 181 ? 394.092 380.591 334.802 1.00 120.66 ? 181 GLU B OE1   1 
ATOM   1374  O  OE2   . GLU A 1 181 ? 393.406 378.650 335.565 1.00 125.05 ? 181 GLU B OE2   1 
ATOM   1375  N  N     . PRO A 1 182 ? 399.560 381.600 334.605 1.00 101.88 ? 182 PRO B N     1 
ATOM   1376  C  CA    . PRO A 1 182 ? 400.579 382.310 333.805 1.00 102.35 ? 182 PRO B CA    1 
ATOM   1377  C  C     . PRO A 1 182 ? 401.893 381.559 333.651 1.00 105.70 ? 182 PRO B C     1 
ATOM   1378  O  O     . PRO A 1 182 ? 402.404 381.466 332.529 1.00 116.64 ? 182 PRO B O     1 
ATOM   1379  C  CB    . PRO A 1 182 ? 400.771 383.622 334.575 1.00 100.74 ? 182 PRO B CB    1 
ATOM   1380  C  CG    . PRO A 1 182 ? 399.504 383.830 335.280 1.00 104.90 ? 182 PRO B CG    1 
ATOM   1381  C  CD    . PRO A 1 182 ? 399.035 382.470 335.676 1.00 107.42 ? 182 PRO B CD    1 
ATOM   1382  N  N     . TYR A 1 183 ? 402.434 380.995 334.734 1.00 96.23  ? 183 TYR B N     1 
ATOM   1383  C  CA    . TYR A 1 183 ? 403.694 380.260 334.643 1.00 97.02  ? 183 TYR B CA    1 
ATOM   1384  C  C     . TYR A 1 183 ? 403.551 379.035 333.749 1.00 95.99  ? 183 TYR B C     1 
ATOM   1385  O  O     . TYR A 1 183 ? 404.365 378.815 332.837 1.00 96.03  ? 183 TYR B O     1 
ATOM   1386  C  CB    . TYR A 1 183 ? 404.153 379.828 336.039 1.00 93.93  ? 183 TYR B CB    1 
ATOM   1387  C  CG    . TYR A 1 183 ? 404.625 380.913 336.999 1.00 93.15  ? 183 TYR B CG    1 
ATOM   1388  C  CD1   . TYR A 1 183 ? 404.716 382.251 336.626 1.00 93.20  ? 183 TYR B CD1   1 
ATOM   1389  C  CD2   . TYR A 1 183 ? 404.990 380.579 338.294 1.00 96.51  ? 183 TYR B CD2   1 
ATOM   1390  C  CE1   . TYR A 1 183 ? 405.154 383.211 337.516 1.00 99.26  ? 183 TYR B CE1   1 
ATOM   1391  C  CE2   . TYR A 1 183 ? 405.424 381.530 339.185 1.00 96.39  ? 183 TYR B CE2   1 
ATOM   1392  C  CZ    . TYR A 1 183 ? 405.506 382.842 338.794 1.00 99.70  ? 183 TYR B CZ    1 
ATOM   1393  O  OH    . TYR A 1 183 ? 405.944 383.784 339.694 1.00 108.36 ? 183 TYR B OH    1 
ATOM   1394  N  N     . ASN A 1 184 ? 402.513 378.227 334.002 1.00 94.54  ? 184 ASN B N     1 
ATOM   1395  C  CA    . ASN A 1 184 ? 402.315 377.008 333.225 1.00 93.39  ? 184 ASN B CA    1 
ATOM   1396  C  C     . ASN A 1 184 ? 402.089 377.326 331.756 1.00 99.55  ? 184 ASN B C     1 
ATOM   1397  O  O     . ASN A 1 184 ? 402.716 376.716 330.881 1.00 106.45 ? 184 ASN B O     1 
ATOM   1398  C  CB    . ASN A 1 184 ? 401.133 376.214 333.781 1.00 96.85  ? 184 ASN B CB    1 
ATOM   1399  C  CG    . ASN A 1 184 ? 401.377 375.714 335.183 1.00 106.09 ? 184 ASN B CG    1 
ATOM   1400  O  OD1   . ASN A 1 184 ? 402.485 375.813 335.706 1.00 108.10 ? 184 ASN B OD1   1 
ATOM   1401  N  ND2   . ASN A 1 184 ? 400.342 375.161 335.800 1.00 110.60 ? 184 ASN B ND2   1 
ATOM   1402  N  N     . ALA A 1 185 ? 401.238 378.314 331.470 1.00 106.83 ? 185 ALA B N     1 
ATOM   1403  C  CA    . ALA A 1 185 ? 400.935 378.673 330.093 1.00 103.52 ? 185 ALA B CA    1 
ATOM   1404  C  C     . ALA A 1 185 ? 402.169 379.199 329.378 1.00 103.06 ? 185 ALA B C     1 
ATOM   1405  O  O     . ALA A 1 185 ? 402.435 378.820 328.233 1.00 109.21 ? 185 ALA B O     1 
ATOM   1406  C  CB    . ALA A 1 185 ? 399.813 379.711 330.067 1.00 99.89  ? 185 ALA B CB    1 
ATOM   1407  N  N     . THR A 1 186 ? 402.945 380.060 330.046 1.00 103.21 ? 186 THR B N     1 
ATOM   1408  C  CA    . THR A 1 186 ? 404.111 380.664 329.412 1.00 102.48 ? 186 THR B CA    1 
ATOM   1409  C  C     . THR A 1 186 ? 405.153 379.610 329.067 1.00 105.71 ? 186 THR B C     1 
ATOM   1410  O  O     . THR A 1 186 ? 405.668 379.581 327.941 1.00 114.41 ? 186 THR B O     1 
ATOM   1411  C  CB    . THR A 1 186 ? 404.704 381.731 330.335 1.00 105.29 ? 186 THR B CB    1 
ATOM   1412  O  OG1   . THR A 1 186 ? 403.792 382.829 330.441 1.00 113.28 ? 186 THR B OG1   1 
ATOM   1413  C  CG2   . THR A 1 186 ? 406.040 382.240 329.808 1.00 101.23 ? 186 THR B CG2   1 
ATOM   1414  N  N     . LEU A 1 187 ? 405.462 378.723 330.019 1.00 97.84  ? 187 LEU B N     1 
ATOM   1415  C  CA    . LEU A 1 187 ? 406.415 377.654 329.734 1.00 96.02  ? 187 LEU B CA    1 
ATOM   1416  C  C     . LEU A 1 187 ? 405.888 376.737 328.635 1.00 97.59  ? 187 LEU B C     1 
ATOM   1417  O  O     . LEU A 1 187 ? 406.651 376.289 327.763 1.00 98.88  ? 187 LEU B O     1 
ATOM   1418  C  CB    . LEU A 1 187 ? 406.711 376.864 331.008 1.00 97.97  ? 187 LEU B CB    1 
ATOM   1419  C  CG    . LEU A 1 187 ? 407.337 377.651 332.166 1.00 93.37  ? 187 LEU B CG    1 
ATOM   1420  C  CD1   . LEU A 1 187 ? 407.141 376.922 333.481 1.00 95.24  ? 187 LEU B CD1   1 
ATOM   1421  C  CD2   . LEU A 1 187 ? 408.812 377.905 331.914 1.00 99.18  ? 187 LEU B CD2   1 
ATOM   1422  N  N     . SER A 1 188 ? 404.573 376.492 328.630 1.00 95.89  ? 188 SER B N     1 
ATOM   1423  C  CA    . SER A 1 188 ? 403.986 375.613 327.629 1.00 93.17  ? 188 SER B CA    1 
ATOM   1424  C  C     . SER A 1 188 ? 404.136 376.187 326.226 1.00 96.75  ? 188 SER B C     1 
ATOM   1425  O  O     . SER A 1 188 ? 404.578 375.482 325.314 1.00 98.86  ? 188 SER B O     1 
ATOM   1426  C  CB    . SER A 1 188 ? 402.515 375.356 327.955 1.00 97.07  ? 188 SER B CB    1 
ATOM   1427  O  OG    . SER A 1 188 ? 402.032 374.222 327.260 1.00 106.14 ? 188 SER B OG    1 
ATOM   1428  N  N     . VAL A 1 189 ? 403.791 377.465 326.028 1.00 108.63 ? 189 VAL B N     1 
ATOM   1429  C  CA    . VAL A 1 189 ? 403.870 377.989 324.661 1.00 110.81 ? 189 VAL B CA    1 
ATOM   1430  C  C     . VAL A 1 189 ? 405.329 378.207 324.277 1.00 111.06 ? 189 VAL B C     1 
ATOM   1431  O  O     . VAL A 1 189 ? 405.678 378.112 323.094 1.00 116.81 ? 189 VAL B O     1 
ATOM   1432  C  CB    . VAL A 1 189 ? 403.037 379.274 324.425 1.00 105.83 ? 189 VAL B CB    1 
ATOM   1433  C  CG1   . VAL A 1 189 ? 403.233 380.327 325.470 1.00 109.08 ? 189 VAL B CG1   1 
ATOM   1434  C  CG2   . VAL A 1 189 ? 403.283 379.862 323.023 1.00 110.49 ? 189 VAL B CG2   1 
ATOM   1435  N  N     . HIS A 1 190 ? 406.210 378.470 325.253 1.00 104.79 ? 190 HIS B N     1 
ATOM   1436  C  CA    . HIS A 1 190 ? 407.637 378.549 324.950 1.00 98.99  ? 190 HIS B CA    1 
ATOM   1437  C  C     . HIS A 1 190 ? 408.153 377.237 324.376 1.00 100.42 ? 190 HIS B C     1 
ATOM   1438  O  O     . HIS A 1 190 ? 408.943 377.237 323.425 1.00 100.71 ? 190 HIS B O     1 
ATOM   1439  C  CB    . HIS A 1 190 ? 408.426 378.915 326.206 1.00 103.92 ? 190 HIS B CB    1 
ATOM   1440  C  CG    . HIS A 1 190 ? 409.878 378.557 326.131 1.00 104.20 ? 190 HIS B CG    1 
ATOM   1441  N  ND1   . HIS A 1 190 ? 410.694 378.968 325.100 1.00 99.96  ? 190 HIS B ND1   1 
ATOM   1442  C  CD2   . HIS A 1 190 ? 410.656 377.815 326.953 1.00 105.89 ? 190 HIS B CD2   1 
ATOM   1443  C  CE1   . HIS A 1 190 ? 411.914 378.500 325.294 1.00 104.00 ? 190 HIS B CE1   1 
ATOM   1444  N  NE2   . HIS A 1 190 ? 411.918 377.798 326.412 1.00 106.85 ? 190 HIS B NE2   1 
ATOM   1445  N  N     . GLN A 1 191 ? 407.713 376.108 324.935 1.00 104.39 ? 191 GLN B N     1 
ATOM   1446  C  CA    . GLN A 1 191 ? 408.091 374.823 324.348 1.00 104.18 ? 191 GLN B CA    1 
ATOM   1447  C  C     . GLN A 1 191 ? 407.354 374.543 323.038 1.00 103.16 ? 191 GLN B C     1 
ATOM   1448  O  O     . GLN A 1 191 ? 407.939 373.967 322.114 1.00 103.56 ? 191 GLN B O     1 
ATOM   1449  C  CB    . GLN A 1 191 ? 407.840 373.699 325.349 1.00 96.97  ? 191 GLN B CB    1 
ATOM   1450  C  CG    . GLN A 1 191 ? 408.798 373.672 326.533 1.00 101.24 ? 191 GLN B CG    1 
ATOM   1451  C  CD    . GLN A 1 191 ? 410.214 373.294 326.144 1.00 108.34 ? 191 GLN B CD    1 
ATOM   1452  O  OE1   . GLN A 1 191 ? 410.443 372.704 325.088 1.00 102.05 ? 191 GLN B OE1   1 
ATOM   1453  N  NE2   . GLN A 1 191 ? 411.172 373.632 326.997 1.00 113.17 ? 191 GLN B NE2   1 
ATOM   1454  N  N     . LEU A 1 192 ? 406.083 374.937 322.933 1.00 104.85 ? 192 LEU B N     1 
ATOM   1455  C  CA    . LEU A 1 192 ? 405.276 374.573 321.767 1.00 99.96  ? 192 LEU B CA    1 
ATOM   1456  C  C     . LEU A 1 192 ? 405.675 375.337 320.511 1.00 100.65 ? 192 LEU B C     1 
ATOM   1457  O  O     . LEU A 1 192 ? 405.613 374.781 319.409 1.00 107.85 ? 192 LEU B O     1 
ATOM   1458  C  CB    . LEU A 1 192 ? 403.785 374.801 322.043 1.00 99.00  ? 192 LEU B CB    1 
ATOM   1459  C  CG    . LEU A 1 192 ? 402.920 373.596 322.419 1.00 101.53 ? 192 LEU B CG    1 
ATOM   1460  C  CD1   . LEU A 1 192 ? 403.284 373.038 323.776 1.00 108.61 ? 192 LEU B CD1   1 
ATOM   1461  C  CD2   . LEU A 1 192 ? 401.453 374.000 322.400 1.00 97.61  ? 192 LEU B CD2   1 
ATOM   1462  N  N     . VAL A 1 193 ? 406.060 376.610 320.647 1.00 106.62 ? 193 VAL B N     1 
ATOM   1463  C  CA    . VAL A 1 193 ? 406.252 377.465 319.476 1.00 105.95 ? 193 VAL B CA    1 
ATOM   1464  C  C     . VAL A 1 193 ? 407.407 376.973 318.615 1.00 107.82 ? 193 VAL B C     1 
ATOM   1465  O  O     . VAL A 1 193 ? 407.392 377.140 317.390 1.00 107.29 ? 193 VAL B O     1 
ATOM   1466  C  CB    . VAL A 1 193 ? 406.454 378.931 319.914 1.00 104.29 ? 193 VAL B CB    1 
ATOM   1467  C  CG1   . VAL A 1 193 ? 407.811 379.129 320.587 1.00 110.90 ? 193 VAL B CG1   1 
ATOM   1468  C  CG2   . VAL A 1 193 ? 406.297 379.874 318.726 1.00 105.56 ? 193 VAL B CG2   1 
ATOM   1469  N  N     . GLU A 1 194 ? 408.418 376.359 319.229 1.00 114.96 ? 194 GLU B N     1 
ATOM   1470  C  CA    . GLU A 1 194 ? 409.537 375.822 318.465 1.00 118.72 ? 194 GLU B CA    1 
ATOM   1471  C  C     . GLU A 1 194 ? 409.178 374.525 317.751 1.00 114.48 ? 194 GLU B C     1 
ATOM   1472  O  O     . GLU A 1 194 ? 409.715 374.253 316.672 1.00 114.96 ? 194 GLU B O     1 
ATOM   1473  C  CB    . GLU A 1 194 ? 410.732 375.595 319.394 1.00 118.59 ? 194 GLU B CB    1 
ATOM   1474  C  CG    . GLU A 1 194 ? 412.078 375.382 318.680 1.00 120.25 ? 194 GLU B CG    1 
ATOM   1475  C  CD    . GLU A 1 194 ? 412.366 373.934 318.287 1.00 123.31 ? 194 GLU B CD    1 
ATOM   1476  O  OE1   . GLU A 1 194 ? 411.617 373.017 318.686 1.00 125.61 ? 194 GLU B OE1   1 
ATOM   1477  O  OE2   . GLU A 1 194 ? 413.361 373.713 317.565 1.00 124.08 ? 194 GLU B OE2   1 
ATOM   1478  N  N     . ASN A 1 195 ? 408.274 373.727 318.321 1.00 99.94  ? 195 ASN B N     1 
ATOM   1479  C  CA    . ASN A 1 195 ? 408.094 372.332 317.939 1.00 100.77 ? 195 ASN B CA    1 
ATOM   1480  C  C     . ASN A 1 195 ? 406.847 372.082 317.097 1.00 107.59 ? 195 ASN B C     1 
ATOM   1481  O  O     . ASN A 1 195 ? 406.932 371.435 316.050 1.00 109.33 ? 195 ASN B O     1 
ATOM   1482  C  CB    . ASN A 1 195 ? 408.044 371.473 319.204 1.00 103.08 ? 195 ASN B CB    1 
ATOM   1483  C  CG    . ASN A 1 195 ? 409.393 371.345 319.878 1.00 107.33 ? 195 ASN B CG    1 
ATOM   1484  O  OD1   . ASN A 1 195 ? 410.296 370.688 319.362 1.00 106.31 ? 195 ASN B OD1   1 
ATOM   1485  N  ND2   . ASN A 1 195 ? 409.536 371.968 321.041 1.00 108.90 ? 195 ASN B ND2   1 
ATOM   1486  N  N     . THR A 1 196 ? 405.688 372.574 317.530 1.00 120.48 ? 196 THR B N     1 
ATOM   1487  C  CA    . THR A 1 196 ? 404.432 372.215 316.888 1.00 115.90 ? 196 THR B CA    1 
ATOM   1488  C  C     . THR A 1 196 ? 404.316 372.852 315.503 1.00 114.55 ? 196 THR B C     1 
ATOM   1489  O  O     . THR A 1 196 ? 405.050 373.779 315.147 1.00 117.60 ? 196 THR B O     1 
ATOM   1490  C  CB    . THR A 1 196 ? 403.244 372.647 317.747 1.00 118.68 ? 196 THR B CB    1 
ATOM   1491  O  OG1   . THR A 1 196 ? 403.317 374.057 317.989 1.00 124.56 ? 196 THR B OG1   1 
ATOM   1492  C  CG2   . THR A 1 196 ? 403.236 371.903 319.069 1.00 117.79 ? 196 THR B CG2   1 
ATOM   1493  N  N     . ASP A 1 197 ? 403.371 372.327 314.720 1.00 105.62 ? 197 ASP B N     1 
ATOM   1494  C  CA    . ASP A 1 197 ? 403.029 372.829 313.392 1.00 105.48 ? 197 ASP B CA    1 
ATOM   1495  C  C     . ASP A 1 197 ? 401.695 373.556 313.353 1.00 105.49 ? 197 ASP B C     1 
ATOM   1496  O  O     . ASP A 1 197 ? 401.555 374.528 312.609 1.00 108.76 ? 197 ASP B O     1 
ATOM   1497  C  CB    . ASP A 1 197 ? 402.992 371.675 312.384 1.00 108.90 ? 197 ASP B CB    1 
ATOM   1498  C  CG    . ASP A 1 197 ? 404.359 371.062 312.144 1.00 114.23 ? 197 ASP B CG    1 
ATOM   1499  O  OD1   . ASP A 1 197 ? 405.370 371.791 312.226 1.00 112.58 ? 197 ASP B OD1   1 
ATOM   1500  O  OD2   . ASP A 1 197 ? 404.424 369.847 311.869 1.00 116.64 ? 197 ASP B OD2   1 
ATOM   1501  N  N     . GLU A 1 198 ? 400.708 373.097 314.124 1.00 109.02 ? 198 GLU B N     1 
ATOM   1502  C  CA    . GLU A 1 198 ? 399.422 373.768 314.256 1.00 106.55 ? 198 GLU B CA    1 
ATOM   1503  C  C     . GLU A 1 198 ? 398.973 373.676 315.704 1.00 109.95 ? 198 GLU B C     1 
ATOM   1504  O  O     . GLU A 1 198 ? 399.090 372.615 316.323 1.00 120.01 ? 198 GLU B O     1 
ATOM   1505  C  CB    . GLU A 1 198 ? 398.340 373.135 313.375 1.00 105.14 ? 198 GLU B CB    1 
ATOM   1506  C  CG    . GLU A 1 198 ? 398.523 373.286 311.877 1.00 111.46 ? 198 GLU B CG    1 
ATOM   1507  C  CD    . GLU A 1 198 ? 397.700 372.268 311.115 1.00 118.23 ? 198 GLU B CD    1 
ATOM   1508  O  OE1   . GLU A 1 198 ? 396.458 372.300 311.242 1.00 119.37 ? 198 GLU B OE1   1 
ATOM   1509  O  OE2   . GLU A 1 198 ? 398.287 371.423 310.412 1.00 118.88 ? 198 GLU B OE2   1 
ATOM   1510  N  N     . THR A 1 199 ? 398.471 374.786 316.248 1.00 100.02 ? 199 THR B N     1 
ATOM   1511  C  CA    . THR A 1 199 ? 397.830 374.792 317.561 1.00 101.78 ? 199 THR B CA    1 
ATOM   1512  C  C     . THR A 1 199 ? 396.590 375.667 317.486 1.00 101.81 ? 199 THR B C     1 
ATOM   1513  O  O     . THR A 1 199 ? 396.670 376.824 317.060 1.00 111.67 ? 199 THR B O     1 
ATOM   1514  C  CB    . THR A 1 199 ? 398.757 375.298 318.674 1.00 104.22 ? 199 THR B CB    1 
ATOM   1515  O  OG1   . THR A 1 199 ? 398.743 376.727 318.700 1.00 106.90 ? 199 THR B OG1   1 
ATOM   1516  C  CG2   . THR A 1 199 ? 400.192 374.816 318.488 1.00 109.81 ? 199 THR B CG2   1 
ATOM   1517  N  N     . TYR A 1 200 ? 395.455 375.108 317.906 1.00 100.01 ? 200 TYR B N     1 
ATOM   1518  C  CA    . TYR A 1 200 ? 394.163 375.784 317.895 1.00 105.31 ? 200 TYR B CA    1 
ATOM   1519  C  C     . TYR A 1 200 ? 393.808 376.124 319.337 1.00 112.82 ? 200 TYR B C     1 
ATOM   1520  O  O     . TYR A 1 200 ? 393.777 375.238 320.197 1.00 114.33 ? 200 TYR B O     1 
ATOM   1521  C  CB    . TYR A 1 200 ? 393.060 374.927 317.257 1.00 99.36  ? 200 TYR B CB    1 
ATOM   1522  C  CG    . TYR A 1 200 ? 393.429 374.168 315.984 1.00 100.19 ? 200 TYR B CG    1 
ATOM   1523  C  CD1   . TYR A 1 200 ? 394.188 373.002 316.023 1.00 104.52 ? 200 TYR B CD1   1 
ATOM   1524  C  CD2   . TYR A 1 200 ? 393.022 374.630 314.740 1.00 104.74 ? 200 TYR B CD2   1 
ATOM   1525  C  CE1   . TYR A 1 200 ? 394.526 372.326 314.876 1.00 110.17 ? 200 TYR B CE1   1 
ATOM   1526  C  CE2   . TYR A 1 200 ? 393.357 373.953 313.581 1.00 103.61 ? 200 TYR B CE2   1 
ATOM   1527  C  CZ    . TYR A 1 200 ? 394.108 372.802 313.657 1.00 110.24 ? 200 TYR B CZ    1 
ATOM   1528  O  OH    . TYR A 1 200 ? 394.449 372.119 312.512 1.00 118.95 ? 200 TYR B OH    1 
ATOM   1529  N  N     . CYS A 1 201 ? 393.539 377.402 319.595 1.00 117.38 ? 201 CYS B N     1 
ATOM   1530  C  CA    . CYS A 1 201 ? 393.411 377.926 320.950 1.00 112.46 ? 201 CYS B CA    1 
ATOM   1531  C  C     . CYS A 1 201 ? 391.935 378.001 321.325 1.00 111.24 ? 201 CYS B C     1 
ATOM   1532  O  O     . CYS A 1 201 ? 391.170 378.752 320.711 1.00 110.64 ? 201 CYS B O     1 
ATOM   1533  C  CB    . CYS A 1 201 ? 394.073 379.298 321.033 1.00 120.28 ? 201 CYS B CB    1 
ATOM   1534  S  SG    . CYS A 1 201 ? 395.858 379.264 320.745 1.00 127.65 ? 201 CYS B SG    1 
ATOM   1535  N  N     . ILE A 1 202 ? 391.541 377.228 322.341 1.00 112.23 ? 202 ILE B N     1 
ATOM   1536  C  CA    . ILE A 1 202 ? 390.173 377.201 322.857 1.00 114.94 ? 202 ILE B CA    1 
ATOM   1537  C  C     . ILE A 1 202 ? 390.163 378.026 324.137 1.00 118.73 ? 202 ILE B C     1 
ATOM   1538  O  O     . ILE A 1 202 ? 391.156 378.051 324.876 1.00 122.31 ? 202 ILE B O     1 
ATOM   1539  C  CB    . ILE A 1 202 ? 389.696 375.751 323.120 1.00 117.62 ? 202 ILE B CB    1 
ATOM   1540  C  CG1   . ILE A 1 202 ? 389.762 374.847 321.857 1.00 115.36 ? 202 ILE B CG1   1 
ATOM   1541  C  CG2   . ILE A 1 202 ? 388.255 375.740 323.705 1.00 115.54 ? 202 ILE B CG2   1 
ATOM   1542  C  CD1   . ILE A 1 202 ? 389.623 375.498 320.498 1.00 115.00 ? 202 ILE B CD1   1 
ATOM   1543  N  N     . ASP A 1 203 ? 389.045 378.707 324.395 1.00 122.59 ? 203 ASP B N     1 
ATOM   1544  C  CA    . ASP A 1 203 ? 388.885 379.597 325.539 1.00 120.32 ? 203 ASP B CA    1 
ATOM   1545  C  C     . ASP A 1 203 ? 387.542 379.321 326.202 1.00 122.85 ? 203 ASP B C     1 
ATOM   1546  O  O     . ASP A 1 203 ? 386.489 379.553 325.597 1.00 131.49 ? 203 ASP B O     1 
ATOM   1547  C  CB    . ASP A 1 203 ? 388.975 381.060 325.099 1.00 124.08 ? 203 ASP B CB    1 
ATOM   1548  C  CG    . ASP A 1 203 ? 389.246 382.007 326.252 1.00 128.36 ? 203 ASP B CG    1 
ATOM   1549  O  OD1   . ASP A 1 203 ? 388.946 381.655 327.411 1.00 132.89 ? 203 ASP B OD1   1 
ATOM   1550  O  OD2   . ASP A 1 203 ? 389.757 383.117 325.994 1.00 126.32 ? 203 ASP B OD2   1 
ATOM   1551  N  N     . ASN A 1 204 ? 387.592 378.871 327.461 1.00 107.59 ? 204 ASN B N     1 
ATOM   1552  C  CA    . ASN A 1 204 ? 386.394 378.386 328.143 1.00 108.51 ? 204 ASN B CA    1 
ATOM   1553  C  C     . ASN A 1 204 ? 385.368 379.497 328.333 1.00 108.09 ? 204 ASN B C     1 
ATOM   1554  O  O     . ASN A 1 204 ? 384.161 379.251 328.239 1.00 114.08 ? 204 ASN B O     1 
ATOM   1555  C  CB    . ASN A 1 204 ? 386.775 377.783 329.501 1.00 109.58 ? 204 ASN B CB    1 
ATOM   1556  C  CG    . ASN A 1 204 ? 387.600 376.488 329.399 1.00 110.03 ? 204 ASN B CG    1 
ATOM   1557  O  OD1   . ASN A 1 204 ? 388.477 376.263 330.231 1.00 113.97 ? 204 ASN B OD1   1 
ATOM   1558  N  ND2   . ASN A 1 204 ? 387.280 375.608 328.449 1.00 109.41 ? 204 ASN B ND2   1 
ATOM   1559  N  N     . GLU A 1 205 ? 385.823 380.726 328.589 1.00 113.52 ? 205 GLU B N     1 
ATOM   1560  C  CA    . GLU A 1 205 ? 384.889 381.846 328.668 1.00 111.66 ? 205 GLU B CA    1 
ATOM   1561  C  C     . GLU A 1 205 ? 384.198 382.079 327.334 1.00 113.43 ? 205 GLU B C     1 
ATOM   1562  O  O     . GLU A 1 205 ? 382.992 382.340 327.298 1.00 116.39 ? 205 GLU B O     1 
ATOM   1563  C  CB    . GLU A 1 205 ? 385.602 383.124 329.110 1.00 116.59 ? 205 GLU B CB    1 
ATOM   1564  C  CG    . GLU A 1 205 ? 384.827 384.000 330.082 1.00 124.84 ? 205 GLU B CG    1 
ATOM   1565  C  CD    . GLU A 1 205 ? 385.723 384.973 330.825 1.00 127.14 ? 205 GLU B CD    1 
ATOM   1566  O  OE1   . GLU A 1 205 ? 385.855 386.129 330.374 1.00 124.88 ? 205 GLU B OE1   1 
ATOM   1567  O  OE2   . GLU A 1 205 ? 386.296 384.586 331.864 1.00 123.93 ? 205 GLU B OE2   1 
ATOM   1568  N  N     . ALA A 1 206 ? 384.942 381.986 326.229 1.00 111.11 ? 206 ALA B N     1 
ATOM   1569  C  CA    . ALA A 1 206 ? 384.331 382.160 324.917 1.00 108.95 ? 206 ALA B CA    1 
ATOM   1570  C  C     . ALA A 1 206 ? 383.307 381.068 324.649 1.00 109.88 ? 206 ALA B C     1 
ATOM   1571  O  O     . ALA A 1 206 ? 382.243 381.334 324.081 1.00 116.38 ? 206 ALA B O     1 
ATOM   1572  C  CB    . ALA A 1 206 ? 385.405 382.169 323.834 1.00 113.94 ? 206 ALA B CB    1 
ATOM   1573  N  N     . LEU A 1 207 ? 383.600 379.834 325.070 1.00 105.39 ? 207 LEU B N     1 
ATOM   1574  C  CA    . LEU A 1 207 ? 382.606 378.769 324.966 1.00 102.39 ? 207 LEU B CA    1 
ATOM   1575  C  C     . LEU A 1 207 ? 381.371 379.073 325.806 1.00 107.33 ? 207 LEU B C     1 
ATOM   1576  O  O     . LEU A 1 207 ? 380.242 378.825 325.363 1.00 110.22 ? 207 LEU B O     1 
ATOM   1577  C  CB    . LEU A 1 207 ? 383.212 377.424 325.376 1.00 101.98 ? 207 LEU B CB    1 
ATOM   1578  C  CG    . LEU A 1 207 ? 384.496 376.959 324.678 1.00 105.87 ? 207 LEU B CG    1 
ATOM   1579  C  CD1   . LEU A 1 207 ? 384.979 375.631 325.234 1.00 109.06 ? 207 LEU B CD1   1 
ATOM   1580  C  CD2   . LEU A 1 207 ? 384.281 376.837 323.188 1.00 109.02 ? 207 LEU B CD2   1 
ATOM   1581  N  N     . TYR A 1 208 ? 381.559 379.607 327.017 1.00 104.95 ? 208 TYR B N     1 
ATOM   1582  C  CA    . TYR A 1 208 ? 380.411 379.949 327.854 1.00 99.54  ? 208 TYR B CA    1 
ATOM   1583  C  C     . TYR A 1 208 ? 379.559 381.033 327.207 1.00 105.46 ? 208 TYR B C     1 
ATOM   1584  O  O     . TYR A 1 208 ? 378.324 380.944 327.212 1.00 109.87 ? 208 TYR B O     1 
ATOM   1585  C  CB    . TYR A 1 208 ? 380.868 380.403 329.246 1.00 101.52 ? 208 TYR B CB    1 
ATOM   1586  C  CG    . TYR A 1 208 ? 381.571 379.359 330.096 1.00 101.00 ? 208 TYR B CG    1 
ATOM   1587  C  CD1   . TYR A 1 208 ? 381.107 378.052 330.170 1.00 100.37 ? 208 TYR B CD1   1 
ATOM   1588  C  CD2   . TYR A 1 208 ? 382.679 379.698 330.862 1.00 102.34 ? 208 TYR B CD2   1 
ATOM   1589  C  CE1   . TYR A 1 208 ? 381.741 377.111 330.949 1.00 101.87 ? 208 TYR B CE1   1 
ATOM   1590  C  CE2   . TYR A 1 208 ? 383.320 378.761 331.647 1.00 101.88 ? 208 TYR B CE2   1 
ATOM   1591  C  CZ    . TYR A 1 208 ? 382.844 377.470 331.689 1.00 103.86 ? 208 TYR B CZ    1 
ATOM   1592  O  OH    . TYR A 1 208 ? 383.476 376.530 332.468 1.00 106.89 ? 208 TYR B OH    1 
ATOM   1593  N  N     . ASP A 1 209 ? 380.194 382.056 326.629 1.00 133.51 ? 209 ASP B N     1 
ATOM   1594  C  CA    . ASP A 1 209 ? 379.409 383.111 325.987 1.00 134.40 ? 209 ASP B CA    1 
ATOM   1595  C  C     . ASP A 1 209 ? 378.722 382.595 324.732 1.00 132.87 ? 209 ASP B C     1 
ATOM   1596  O  O     . ASP A 1 209 ? 377.602 383.010 324.430 1.00 133.38 ? 209 ASP B O     1 
ATOM   1597  C  CB    . ASP A 1 209 ? 380.231 384.365 325.649 1.00 138.87 ? 209 ASP B CB    1 
ATOM   1598  C  CG    . ASP A 1 209 ? 381.312 384.679 326.661 1.00 142.33 ? 209 ASP B CG    1 
ATOM   1599  O  OD1   . ASP A 1 209 ? 382.495 384.746 326.265 1.00 143.06 ? 209 ASP B OD1   1 
ATOM   1600  O  OD2   . ASP A 1 209 ? 380.978 384.864 327.849 1.00 142.44 ? 209 ASP B OD2   1 
ATOM   1601  N  N     . ILE A 1 210 ? 379.372 381.697 323.985 1.00 123.83 ? 210 ILE B N     1 
ATOM   1602  C  CA    . ILE A 1 210 ? 378.729 381.109 322.811 1.00 121.87 ? 210 ILE B CA    1 
ATOM   1603  C  C     . ILE A 1 210 ? 377.490 380.331 323.234 1.00 117.87 ? 210 ILE B C     1 
ATOM   1604  O  O     . ILE A 1 210 ? 376.414 380.464 322.635 1.00 123.48 ? 210 ILE B O     1 
ATOM   1605  C  CB    . ILE A 1 210 ? 379.717 380.213 322.037 1.00 118.75 ? 210 ILE B CB    1 
ATOM   1606  C  CG1   . ILE A 1 210 ? 380.791 381.049 321.337 1.00 123.40 ? 210 ILE B CG1   1 
ATOM   1607  C  CG2   . ILE A 1 210 ? 378.989 379.363 320.989 1.00 113.32 ? 210 ILE B CG2   1 
ATOM   1608  C  CD1   . ILE A 1 210 ? 382.090 380.298 321.104 1.00 119.79 ? 210 ILE B CD1   1 
ATOM   1609  N  N     . CYS A 1 211 ? 377.624 379.526 324.291 1.00 119.90 ? 211 CYS B N     1 
ATOM   1610  C  CA    . CYS A 1 211 ? 376.502 378.734 324.782 1.00 121.06 ? 211 CYS B CA    1 
ATOM   1611  C  C     . CYS A 1 211 ? 375.365 379.628 325.259 1.00 118.55 ? 211 CYS B C     1 
ATOM   1612  O  O     . CYS A 1 211 ? 374.189 379.343 325.007 1.00 122.77 ? 211 CYS B O     1 
ATOM   1613  C  CB    . CYS A 1 211 ? 376.971 377.814 325.910 1.00 118.33 ? 211 CYS B CB    1 
ATOM   1614  S  SG    . CYS A 1 211 ? 377.918 376.379 325.355 1.00 122.01 ? 211 CYS B SG    1 
ATOM   1615  N  N     . PHE A 1 212 ? 375.698 380.719 325.950 1.00 123.69 ? 212 PHE B N     1 
ATOM   1616  C  CA    . PHE A 1 212 ? 374.655 381.580 326.496 1.00 122.61 ? 212 PHE B CA    1 
ATOM   1617  C  C     . PHE A 1 212 ? 373.972 382.403 325.407 1.00 123.88 ? 212 PHE B C     1 
ATOM   1618  O  O     . PHE A 1 212 ? 372.742 382.517 325.393 1.00 126.07 ? 212 PHE B O     1 
ATOM   1619  C  CB    . PHE A 1 212 ? 375.245 382.495 327.569 1.00 124.52 ? 212 PHE B CB    1 
ATOM   1620  C  CG    . PHE A 1 212 ? 374.223 383.336 328.283 1.00 125.83 ? 212 PHE B CG    1 
ATOM   1621  C  CD1   . PHE A 1 212 ? 373.192 382.748 328.998 1.00 126.56 ? 212 PHE B CD1   1 
ATOM   1622  C  CD2   . PHE A 1 212 ? 374.299 384.717 328.246 1.00 126.10 ? 212 PHE B CD2   1 
ATOM   1623  C  CE1   . PHE A 1 212 ? 372.255 383.518 329.654 1.00 129.69 ? 212 PHE B CE1   1 
ATOM   1624  C  CE2   . PHE A 1 212 ? 373.364 385.494 328.902 1.00 126.78 ? 212 PHE B CE2   1 
ATOM   1625  C  CZ    . PHE A 1 212 ? 372.341 384.893 329.607 1.00 128.75 ? 212 PHE B CZ    1 
ATOM   1626  N  N     . ARG A 1 213 ? 374.746 382.995 324.493 1.00 135.98 ? 213 ARG B N     1 
ATOM   1627  C  CA    . ARG A 1 213 ? 374.165 383.893 323.498 1.00 136.89 ? 213 ARG B CA    1 
ATOM   1628  C  C     . ARG A 1 213 ? 373.445 383.128 322.396 1.00 136.63 ? 213 ARG B C     1 
ATOM   1629  O  O     . ARG A 1 213 ? 372.349 383.525 321.985 1.00 138.59 ? 213 ARG B O     1 
ATOM   1630  C  CB    . ARG A 1 213 ? 375.241 384.788 322.876 1.00 143.00 ? 213 ARG B CB    1 
ATOM   1631  C  CG    . ARG A 1 213 ? 375.165 386.252 323.306 1.00 143.80 ? 213 ARG B CG    1 
ATOM   1632  C  CD    . ARG A 1 213 ? 376.122 387.164 322.526 1.00 143.21 ? 213 ARG B CD    1 
ATOM   1633  N  NE    . ARG A 1 213 ? 377.423 386.554 322.251 1.00 145.94 ? 213 ARG B NE    1 
ATOM   1634  C  CZ    . ARG A 1 213 ? 378.478 386.571 323.061 1.00 146.16 ? 213 ARG B CZ    1 
ATOM   1635  N  NH1   . ARG A 1 213 ? 378.445 387.160 324.249 1.00 143.82 ? 213 ARG B NH1   1 
ATOM   1636  N  NH2   . ARG A 1 213 ? 379.600 385.973 322.671 1.00 145.84 ? 213 ARG B NH2   1 
ATOM   1637  N  N     . THR A 1 214 ? 374.040 382.038 321.904 1.00 130.58 ? 214 THR B N     1 
ATOM   1638  C  CA    . THR A 1 214 ? 373.515 381.322 320.745 1.00 132.33 ? 214 THR B CA    1 
ATOM   1639  C  C     . THR A 1 214 ? 372.672 380.119 321.158 1.00 131.76 ? 214 THR B C     1 
ATOM   1640  O  O     . THR A 1 214 ? 371.504 380.017 320.773 1.00 134.30 ? 214 THR B O     1 
ATOM   1641  C  CB    . THR A 1 214 ? 374.670 380.888 319.832 1.00 132.96 ? 214 THR B CB    1 
ATOM   1642  O  OG1   . THR A 1 214 ? 375.708 381.876 319.869 1.00 132.27 ? 214 THR B OG1   1 
ATOM   1643  C  CG2   . THR A 1 214 ? 374.183 380.747 318.401 1.00 134.03 ? 214 THR B CG2   1 
ATOM   1644  N  N     . LEU A 1 215 ? 373.242 379.205 321.943 1.00 123.81 ? 215 LEU B N     1 
ATOM   1645  C  CA    . LEU A 1 215 ? 372.509 378.018 322.366 1.00 125.03 ? 215 LEU B CA    1 
ATOM   1646  C  C     . LEU A 1 215 ? 371.534 378.293 323.510 1.00 126.65 ? 215 LEU B C     1 
ATOM   1647  O  O     . LEU A 1 215 ? 370.618 377.491 323.722 1.00 124.91 ? 215 LEU B O     1 
ATOM   1648  C  CB    . LEU A 1 215 ? 373.494 376.915 322.769 1.00 122.08 ? 215 LEU B CB    1 
ATOM   1649  C  CG    . LEU A 1 215 ? 374.415 376.393 321.657 1.00 118.72 ? 215 LEU B CG    1 
ATOM   1650  C  CD1   . LEU A 1 215 ? 375.597 375.619 322.228 1.00 123.07 ? 215 LEU B CD1   1 
ATOM   1651  C  CD2   . LEU A 1 215 ? 373.641 375.520 320.678 1.00 123.13 ? 215 LEU B CD2   1 
ATOM   1652  N  N     . LYS A 1 216 ? 371.696 379.405 324.238 1.00 142.57 ? 216 LYS B N     1 
ATOM   1653  C  CA    . LYS A 1 216 ? 370.813 379.774 325.354 1.00 139.93 ? 216 LYS B CA    1 
ATOM   1654  C  C     . LYS A 1 216 ? 370.761 378.694 326.436 1.00 137.86 ? 216 LYS B C     1 
ATOM   1655  O  O     . LYS A 1 216 ? 369.752 378.539 327.129 1.00 138.15 ? 216 LYS B O     1 
ATOM   1656  C  CB    . LYS A 1 216 ? 369.385 380.126 324.890 1.00 138.40 ? 216 LYS B CB    1 
ATOM   1657  C  CG    . LYS A 1 216 ? 369.135 380.607 323.449 1.00 140.24 ? 216 LYS B CG    1 
ATOM   1658  C  CD    . LYS A 1 216 ? 370.033 381.767 322.964 1.00 144.72 ? 216 LYS B CD    1 
ATOM   1659  C  CE    . LYS A 1 216 ? 369.835 383.039 323.804 1.00 145.94 ? 216 LYS B CE    1 
ATOM   1660  N  NZ    . LYS A 1 216 ? 368.408 383.407 324.035 1.00 143.70 ? 216 LYS B NZ    1 
ATOM   1661  N  N     . LEU A 1 217 ? 371.853 377.963 326.629 1.00 127.03 ? 217 LEU B N     1 
ATOM   1662  C  CA    . LEU A 1 217 ? 371.899 376.946 327.671 1.00 127.10 ? 217 LEU B CA    1 
ATOM   1663  C  C     . LEU A 1 217 ? 372.002 377.628 329.028 1.00 131.27 ? 217 LEU B C     1 
ATOM   1664  O  O     . LEU A 1 217 ? 372.953 378.374 329.285 1.00 133.46 ? 217 LEU B O     1 
ATOM   1665  C  CB    . LEU A 1 217 ? 373.077 376.001 327.451 1.00 127.58 ? 217 LEU B CB    1 
ATOM   1666  C  CG    . LEU A 1 217 ? 373.052 375.178 326.161 1.00 124.38 ? 217 LEU B CG    1 
ATOM   1667  C  CD1   . LEU A 1 217 ? 374.399 374.516 325.930 1.00 126.14 ? 217 LEU B CD1   1 
ATOM   1668  C  CD2   . LEU A 1 217 ? 371.943 374.136 326.196 1.00 123.30 ? 217 LEU B CD2   1 
ATOM   1669  N  N     . THR A 1 218 ? 371.013 377.386 329.892 1.00 141.81 ? 218 THR B N     1 
ATOM   1670  C  CA    . THR A 1 218 ? 371.038 377.980 331.223 1.00 142.74 ? 218 THR B CA    1 
ATOM   1671  C  C     . THR A 1 218 ? 372.104 377.346 332.107 1.00 141.70 ? 218 THR B C     1 
ATOM   1672  O  O     . THR A 1 218 ? 372.678 378.029 332.963 1.00 142.52 ? 218 THR B O     1 
ATOM   1673  C  CB    . THR A 1 218 ? 369.667 377.848 331.886 1.00 142.61 ? 218 THR B CB    1 
ATOM   1674  O  OG1   . THR A 1 218 ? 369.079 376.590 331.529 1.00 141.54 ? 218 THR B OG1   1 
ATOM   1675  C  CG2   . THR A 1 218 ? 368.748 378.981 331.454 1.00 140.51 ? 218 THR B CG2   1 
ATOM   1676  N  N     . THR A 1 219 ? 372.377 376.054 331.916 1.00 132.35 ? 219 THR B N     1 
ATOM   1677  C  CA    . THR A 1 219 ? 373.323 375.292 332.732 1.00 134.90 ? 219 THR B CA    1 
ATOM   1678  C  C     . THR A 1 219 ? 374.303 374.573 331.813 1.00 131.68 ? 219 THR B C     1 
ATOM   1679  O  O     . THR A 1 219 ? 374.243 373.347 331.659 1.00 127.32 ? 219 THR B O     1 
ATOM   1680  C  CB    . THR A 1 219 ? 372.587 374.292 333.625 1.00 134.53 ? 219 THR B CB    1 
ATOM   1681  O  OG1   . THR A 1 219 ? 371.747 373.455 332.820 1.00 127.94 ? 219 THR B OG1   1 
ATOM   1682  C  CG2   . THR A 1 219 ? 371.738 375.019 334.657 1.00 134.61 ? 219 THR B CG2   1 
ATOM   1683  N  N     . PRO A 1 220 ? 375.224 375.308 331.180 1.00 121.81 ? 220 PRO B N     1 
ATOM   1684  C  CA    . PRO A 1 220 ? 376.208 374.662 330.301 1.00 118.11 ? 220 PRO B CA    1 
ATOM   1685  C  C     . PRO A 1 220 ? 377.300 373.986 331.113 1.00 121.02 ? 220 PRO B C     1 
ATOM   1686  O  O     . PRO A 1 220 ? 378.180 374.648 331.673 1.00 125.20 ? 220 PRO B O     1 
ATOM   1687  C  CB    . PRO A 1 220 ? 376.751 375.835 329.473 1.00 122.33 ? 220 PRO B CB    1 
ATOM   1688  C  CG    . PRO A 1 220 ? 376.622 377.004 330.370 1.00 123.30 ? 220 PRO B CG    1 
ATOM   1689  C  CD    . PRO A 1 220 ? 375.390 376.773 331.199 1.00 124.28 ? 220 PRO B CD    1 
ATOM   1690  N  N     . THR A 1 221 ? 377.245 372.659 331.178 1.00 107.36 ? 221 THR B N     1 
ATOM   1691  C  CA    . THR A 1 221 ? 378.286 371.883 331.831 1.00 110.89 ? 221 THR B CA    1 
ATOM   1692  C  C     . THR A 1 221 ? 379.467 371.719 330.881 1.00 110.46 ? 221 THR B C     1 
ATOM   1693  O  O     . THR A 1 221 ? 379.424 372.129 329.718 1.00 112.08 ? 221 THR B O     1 
ATOM   1694  C  CB    . THR A 1 221 ? 377.750 370.521 332.265 1.00 107.45 ? 221 THR B CB    1 
ATOM   1695  O  OG1   . THR A 1 221 ? 377.440 369.736 331.107 1.00 107.70 ? 221 THR B OG1   1 
ATOM   1696  C  CG2   . THR A 1 221 ? 376.501 370.680 333.116 1.00 108.27 ? 221 THR B CG2   1 
ATOM   1697  N  N     . TYR A 1 222 ? 380.538 371.092 331.373 1.00 95.08  ? 222 TYR B N     1 
ATOM   1698  C  CA    . TYR A 1 222 ? 381.696 370.836 330.524 1.00 94.09  ? 222 TYR B CA    1 
ATOM   1699  C  C     . TYR A 1 222 ? 381.386 369.872 329.387 1.00 95.62  ? 222 TYR B C     1 
ATOM   1700  O  O     . TYR A 1 222 ? 382.133 369.843 328.403 1.00 101.55 ? 222 TYR B O     1 
ATOM   1701  C  CB    . TYR A 1 222 ? 382.859 370.282 331.354 1.00 91.13  ? 222 TYR B CB    1 
ATOM   1702  C  CG    . TYR A 1 222 ? 383.666 371.322 332.106 1.00 91.00  ? 222 TYR B CG    1 
ATOM   1703  C  CD1   . TYR A 1 222 ? 384.387 372.300 331.431 1.00 91.14  ? 222 TYR B CD1   1 
ATOM   1704  C  CD2   . TYR A 1 222 ? 383.719 371.315 333.491 1.00 96.74  ? 222 TYR B CD2   1 
ATOM   1705  C  CE1   . TYR A 1 222 ? 385.124 373.243 332.114 1.00 94.24  ? 222 TYR B CE1   1 
ATOM   1706  C  CE2   . TYR A 1 222 ? 384.457 372.255 334.182 1.00 98.32  ? 222 TYR B CE2   1 
ATOM   1707  C  CZ    . TYR A 1 222 ? 385.157 373.216 333.489 1.00 98.43  ? 222 TYR B CZ    1 
ATOM   1708  O  OH    . TYR A 1 222 ? 385.893 374.156 334.171 1.00 105.35 ? 222 TYR B OH    1 
ATOM   1709  N  N     . GLY A 1 223 ? 380.316 369.080 329.500 1.00 89.71  ? 223 GLY B N     1 
ATOM   1710  C  CA    . GLY A 1 223 ? 379.932 368.209 328.403 1.00 93.51  ? 223 GLY B CA    1 
ATOM   1711  C  C     . GLY A 1 223 ? 379.601 368.972 327.135 1.00 100.70 ? 223 GLY B C     1 
ATOM   1712  O  O     . GLY A 1 223 ? 380.001 368.574 326.043 1.00 105.27 ? 223 GLY B O     1 
ATOM   1713  N  N     . ASP A 1 224 ? 378.893 370.096 327.263 1.00 111.79 ? 224 ASP B N     1 
ATOM   1714  C  CA    . ASP A 1 224 ? 378.537 370.880 326.081 1.00 112.28 ? 224 ASP B CA    1 
ATOM   1715  C  C     . ASP A 1 224 ? 379.764 371.546 325.468 1.00 114.52 ? 224 ASP B C     1 
ATOM   1716  O  O     . ASP A 1 224 ? 379.903 371.607 324.238 1.00 117.45 ? 224 ASP B O     1 
ATOM   1717  C  CB    . ASP A 1 224 ? 377.488 371.928 326.447 1.00 114.35 ? 224 ASP B CB    1 
ATOM   1718  C  CG    . ASP A 1 224 ? 376.296 371.333 327.173 1.00 117.25 ? 224 ASP B CG    1 
ATOM   1719  O  OD1   . ASP A 1 224 ? 375.471 370.666 326.517 1.00 114.09 ? 224 ASP B OD1   1 
ATOM   1720  O  OD2   . ASP A 1 224 ? 376.189 371.530 328.401 1.00 117.75 ? 224 ASP B OD2   1 
ATOM   1721  N  N     . LEU A 1 225 ? 380.656 372.061 326.315 1.00 103.04 ? 225 LEU B N     1 
ATOM   1722  C  CA    . LEU A 1 225 ? 381.900 372.655 325.838 1.00 103.77 ? 225 LEU B CA    1 
ATOM   1723  C  C     . LEU A 1 225 ? 382.746 371.633 325.089 1.00 107.68 ? 225 LEU B C     1 
ATOM   1724  O  O     . LEU A 1 225 ? 383.251 371.905 323.988 1.00 109.91 ? 225 LEU B O     1 
ATOM   1725  C  CB    . LEU A 1 225 ? 382.667 373.228 327.033 1.00 103.25 ? 225 LEU B CB    1 
ATOM   1726  C  CG    . LEU A 1 225 ? 382.186 374.587 327.569 1.00 106.85 ? 225 LEU B CG    1 
ATOM   1727  C  CD1   . LEU A 1 225 ? 380.968 374.454 328.468 1.00 107.85 ? 225 LEU B CD1   1 
ATOM   1728  C  CD2   . LEU A 1 225 ? 383.280 375.300 328.361 1.00 109.41 ? 225 LEU B CD2   1 
ATOM   1729  N  N     . ASN A 1 226 ? 382.887 370.437 325.660 1.00 95.46  ? 226 ASN B N     1 
ATOM   1730  C  CA    . ASN A 1 226 ? 383.604 369.374 324.975 1.00 92.85  ? 226 ASN B CA    1 
ATOM   1731  C  C     . ASN A 1 226 ? 382.875 368.936 323.713 1.00 94.23  ? 226 ASN B C     1 
ATOM   1732  O  O     . ASN A 1 226 ? 383.519 368.518 322.748 1.00 100.38 ? 226 ASN B O     1 
ATOM   1733  C  CB    . ASN A 1 226 ? 383.802 368.197 325.925 1.00 89.72  ? 226 ASN B CB    1 
ATOM   1734  C  CG    . ASN A 1 226 ? 384.603 368.576 327.155 1.00 88.11  ? 226 ASN B CG    1 
ATOM   1735  O  OD1   . ASN A 1 226 ? 385.126 369.685 327.247 1.00 83.82  ? 226 ASN B OD1   1 
ATOM   1736  N  ND2   . ASN A 1 226 ? 384.697 367.659 328.109 1.00 95.71  ? 226 ASN B ND2   1 
ATOM   1737  N  N     . HIS A 1 227 ? 381.542 369.025 323.698 1.00 99.31  ? 227 HIS B N     1 
ATOM   1738  C  CA    . HIS A 1 227 ? 380.787 368.715 322.489 1.00 99.31  ? 227 HIS B CA    1 
ATOM   1739  C  C     . HIS A 1 227 ? 381.154 369.672 321.363 1.00 100.48 ? 227 HIS B C     1 
ATOM   1740  O  O     . HIS A 1 227 ? 381.377 369.255 320.220 1.00 104.03 ? 227 HIS B O     1 
ATOM   1741  C  CB    . HIS A 1 227 ? 379.287 368.773 322.773 1.00 105.68 ? 227 HIS B CB    1 
ATOM   1742  C  CG    . HIS A 1 227 ? 378.467 367.963 321.819 1.00 110.07 ? 227 HIS B CG    1 
ATOM   1743  N  ND1   . HIS A 1 227 ? 377.613 366.965 322.237 1.00 102.31 ? 227 HIS B ND1   1 
ATOM   1744  C  CD2   . HIS A 1 227 ? 378.361 368.008 320.470 1.00 111.08 ? 227 HIS B CD2   1 
ATOM   1745  C  CE1   . HIS A 1 227 ? 377.020 366.427 321.186 1.00 105.11 ? 227 HIS B CE1   1 
ATOM   1746  N  NE2   . HIS A 1 227 ? 377.457 367.042 320.102 1.00 112.84 ? 227 HIS B NE2   1 
ATOM   1747  N  N     . LEU A 1 228 ? 381.230 370.966 321.678 1.00 104.90 ? 228 LEU B N     1 
ATOM   1748  C  CA    . LEU A 1 228 ? 381.612 371.954 320.669 1.00 108.66 ? 228 LEU B CA    1 
ATOM   1749  C  C     . LEU A 1 228 ? 383.040 371.725 320.183 1.00 108.52 ? 228 LEU B C     1 
ATOM   1750  O  O     . LEU A 1 228 ? 383.323 371.816 318.977 1.00 109.56 ? 228 LEU B O     1 
ATOM   1751  C  CB    . LEU A 1 228 ? 381.464 373.371 321.228 1.00 103.03 ? 228 LEU B CB    1 
ATOM   1752  C  CG    . LEU A 1 228 ? 380.147 374.081 320.908 1.00 102.61 ? 228 LEU B CG    1 
ATOM   1753  C  CD1   . LEU A 1 228 ? 378.963 373.367 321.540 1.00 105.46 ? 228 LEU B CD1   1 
ATOM   1754  C  CD2   . LEU A 1 228 ? 380.204 375.524 321.373 1.00 106.60 ? 228 LEU B CD2   1 
ATOM   1755  N  N     . VAL A 1 229 ? 383.954 371.421 321.106 1.00 103.13 ? 229 VAL B N     1 
ATOM   1756  C  CA    . VAL A 1 229 ? 385.340 371.192 320.706 1.00 100.71 ? 229 VAL B CA    1 
ATOM   1757  C  C     . VAL A 1 229 ? 385.445 369.945 319.831 1.00 102.91 ? 229 VAL B C     1 
ATOM   1758  O  O     . VAL A 1 229 ? 386.185 369.929 318.840 1.00 111.79 ? 229 VAL B O     1 
ATOM   1759  C  CB    . VAL A 1 229 ? 386.249 371.110 321.946 1.00 103.87 ? 229 VAL B CB    1 
ATOM   1760  C  CG1   . VAL A 1 229 ? 387.657 370.654 321.559 1.00 102.13 ? 229 VAL B CG1   1 
ATOM   1761  C  CG2   . VAL A 1 229 ? 386.306 372.464 322.645 1.00 105.32 ? 229 VAL B CG2   1 
ATOM   1762  N  N     . SER A 1 230 ? 384.695 368.891 320.169 1.00 108.05 ? 230 SER B N     1 
ATOM   1763  C  CA    . SER A 1 230 ? 384.673 367.688 319.343 1.00 111.78 ? 230 SER B CA    1 
ATOM   1764  C  C     . SER A 1 230 ? 384.092 367.978 317.969 1.00 114.11 ? 230 SER B C     1 
ATOM   1765  O  O     . SER A 1 230 ? 384.521 367.387 316.969 1.00 115.16 ? 230 SER B O     1 
ATOM   1766  C  CB    . SER A 1 230 ? 383.858 366.598 320.028 1.00 118.19 ? 230 SER B CB    1 
ATOM   1767  O  OG    . SER A 1 230 ? 382.666 367.136 320.551 1.00 125.26 ? 230 SER B OG    1 
ATOM   1768  N  N     . ALA A 1 231 ? 383.098 368.866 317.908 1.00 105.90 ? 231 ALA B N     1 
ATOM   1769  C  CA    . ALA A 1 231 ? 382.553 369.286 316.624 1.00 107.53 ? 231 ALA B CA    1 
ATOM   1770  C  C     . ALA A 1 231 ? 383.630 369.930 315.768 1.00 106.76 ? 231 ALA B C     1 
ATOM   1771  O  O     . ALA A 1 231 ? 383.744 369.640 314.572 1.00 107.11 ? 231 ALA B O     1 
ATOM   1772  C  CB    . ALA A 1 231 ? 381.403 370.266 316.843 1.00 109.70 ? 231 ALA B CB    1 
ATOM   1773  N  N     . THR A 1 232 ? 384.447 370.790 316.377 1.00 104.34 ? 232 THR B N     1 
ATOM   1774  C  CA    . THR A 1 232 ? 385.540 371.412 315.632 1.00 100.47 ? 232 THR B CA    1 
ATOM   1775  C  C     . THR A 1 232 ? 386.575 370.385 315.176 1.00 102.45 ? 232 THR B C     1 
ATOM   1776  O  O     . THR A 1 232 ? 387.099 370.480 314.058 1.00 109.56 ? 232 THR B O     1 
ATOM   1777  C  CB    . THR A 1 232 ? 386.198 372.500 316.476 1.00 102.09 ? 232 THR B CB    1 
ATOM   1778  O  OG1   . THR A 1 232 ? 385.241 373.532 316.740 1.00 105.20 ? 232 THR B OG1   1 
ATOM   1779  C  CG2   . THR A 1 232 ? 387.395 373.095 315.748 1.00 97.62  ? 232 THR B CG2   1 
ATOM   1780  N  N     . MET A 1 233 ? 386.897 369.411 316.035 1.00 110.75 ? 233 MET B N     1 
ATOM   1781  C  CA    . MET A 1 233 ? 387.862 368.376 315.656 1.00 108.24 ? 233 MET B CA    1 
ATOM   1782  C  C     . MET A 1 233 ? 387.357 367.577 314.459 1.00 116.48 ? 233 MET B C     1 
ATOM   1783  O  O     . MET A 1 233 ? 388.081 367.377 313.471 1.00 120.51 ? 233 MET B O     1 
ATOM   1784  C  CB    . MET A 1 233 ? 388.122 367.424 316.826 1.00 107.37 ? 233 MET B CB    1 
ATOM   1785  C  CG    . MET A 1 233 ? 388.474 368.052 318.155 1.00 112.99 ? 233 MET B CG    1 
ATOM   1786  S  SD    . MET A 1 233 ? 389.824 367.201 318.990 1.00 131.47 ? 233 MET B SD    1 
ATOM   1787  C  CE    . MET A 1 233 ? 390.396 368.469 320.109 1.00 116.45 ? 233 MET B CE    1 
ATOM   1788  N  N     . SER A 1 234 ? 386.104 367.119 314.535 1.00 105.79 ? 234 SER B N     1 
ATOM   1789  C  CA    . SER A 1 234 ? 385.514 366.357 313.441 1.00 106.20 ? 234 SER B CA    1 
ATOM   1790  C  C     . SER A 1 234 ? 385.412 367.197 312.178 1.00 109.84 ? 234 SER B C     1 
ATOM   1791  O  O     . SER A 1 234 ? 385.542 366.667 311.070 1.00 118.04 ? 234 SER B O     1 
ATOM   1792  C  CB    . SER A 1 234 ? 384.134 365.837 313.852 1.00 106.82 ? 234 SER B CB    1 
ATOM   1793  O  OG    . SER A 1 234 ? 383.388 365.398 312.730 1.00 115.13 ? 234 SER B OG    1 
ATOM   1794  N  N     . GLY A 1 235 ? 385.183 368.502 312.321 1.00 98.53  ? 235 GLY B N     1 
ATOM   1795  C  CA    . GLY A 1 235 ? 385.140 369.360 311.151 1.00 99.94  ? 235 GLY B CA    1 
ATOM   1796  C  C     . GLY A 1 235 ? 386.486 369.490 310.466 1.00 99.47  ? 235 GLY B C     1 
ATOM   1797  O  O     . GLY A 1 235 ? 386.579 369.389 309.239 1.00 104.08 ? 235 GLY B O     1 
ATOM   1798  N  N     . VAL A 1 236 ? 387.549 369.722 311.242 1.00 101.79 ? 236 VAL B N     1 
ATOM   1799  C  CA    . VAL A 1 236 ? 388.853 369.940 310.617 1.00 98.40  ? 236 VAL B CA    1 
ATOM   1800  C  C     . VAL A 1 236 ? 389.379 368.647 310.005 1.00 98.10  ? 236 VAL B C     1 
ATOM   1801  O  O     . VAL A 1 236 ? 389.981 368.666 308.925 1.00 95.00  ? 236 VAL B O     1 
ATOM   1802  C  CB    . VAL A 1 236 ? 389.869 370.561 311.600 1.00 94.07  ? 236 VAL B CB    1 
ATOM   1803  C  CG1   . VAL A 1 236 ? 389.414 371.948 312.029 1.00 98.92  ? 236 VAL B CG1   1 
ATOM   1804  C  CG2   . VAL A 1 236 ? 390.141 369.676 312.817 1.00 101.91 ? 236 VAL B CG2   1 
ATOM   1805  N  N     . THR A 1 237 ? 389.154 367.508 310.667 1.00 104.99 ? 237 THR B N     1 
ATOM   1806  C  CA    . THR A 1 237 ? 389.702 366.234 310.211 1.00 105.01 ? 237 THR B CA    1 
ATOM   1807  C  C     . THR A 1 237 ? 388.740 365.452 309.310 1.00 104.28 ? 237 THR B C     1 
ATOM   1808  O  O     . THR A 1 237 ? 388.885 364.231 309.179 1.00 109.00 ? 237 THR B O     1 
ATOM   1809  C  CB    . THR A 1 237 ? 390.122 365.389 311.420 1.00 108.21 ? 237 THR B CB    1 
ATOM   1810  O  OG1   . THR A 1 237 ? 391.010 364.349 310.991 1.00 107.83 ? 237 THR B OG1   1 
ATOM   1811  C  CG2   . THR A 1 237 ? 388.923 364.774 312.138 1.00 106.64 ? 237 THR B CG2   1 
ATOM   1812  N  N     . THR A 1 238 ? 387.776 366.126 308.675 1.00 102.09 ? 238 THR B N     1 
ATOM   1813  C  CA    . THR A 1 238 ? 386.769 365.423 307.884 1.00 104.21 ? 238 THR B CA    1 
ATOM   1814  C  C     . THR A 1 238 ? 387.280 364.990 306.514 1.00 107.47 ? 238 THR B C     1 
ATOM   1815  O  O     . THR A 1 238 ? 386.800 363.987 305.974 1.00 112.86 ? 238 THR B O     1 
ATOM   1816  C  CB    . THR A 1 238 ? 385.521 366.295 307.706 1.00 105.49 ? 238 THR B CB    1 
ATOM   1817  O  OG1   . THR A 1 238 ? 384.468 365.508 307.135 1.00 113.38 ? 238 THR B OG1   1 
ATOM   1818  C  CG2   . THR A 1 238 ? 385.793 367.490 306.794 1.00 102.42 ? 238 THR B CG2   1 
ATOM   1819  N  N     . CYS A 1 239 ? 388.233 365.722 305.934 1.00 106.28 ? 239 CYS B N     1 
ATOM   1820  C  CA    . CYS A 1 239 ? 388.608 365.474 304.545 1.00 105.00 ? 239 CYS B CA    1 
ATOM   1821  C  C     . CYS A 1 239 ? 389.331 364.144 304.375 1.00 107.62 ? 239 CYS B C     1 
ATOM   1822  O  O     . CYS A 1 239 ? 389.257 363.537 303.301 1.00 108.51 ? 239 CYS B O     1 
ATOM   1823  C  CB    . CYS A 1 239 ? 389.463 366.628 304.034 1.00 108.54 ? 239 CYS B CB    1 
ATOM   1824  S  SG    . CYS A 1 239 ? 388.582 368.204 304.060 1.00 116.10 ? 239 CYS B SG    1 
ATOM   1825  N  N     . LEU A 1 240 ? 390.032 363.678 305.408 1.00 107.50 ? 240 LEU B N     1 
ATOM   1826  C  CA    . LEU A 1 240 ? 390.614 362.342 305.366 1.00 108.29 ? 240 LEU B CA    1 
ATOM   1827  C  C     . LEU A 1 240 ? 389.571 361.245 305.522 1.00 108.98 ? 240 LEU B C     1 
ATOM   1828  O  O     . LEU A 1 240 ? 389.791 360.130 305.039 1.00 109.51 ? 240 LEU B O     1 
ATOM   1829  C  CB    . LEU A 1 240 ? 391.656 362.184 306.472 1.00 106.61 ? 240 LEU B CB    1 
ATOM   1830  C  CG    . LEU A 1 240 ? 392.730 363.259 306.617 1.00 105.42 ? 240 LEU B CG    1 
ATOM   1831  C  CD1   . LEU A 1 240 ? 393.753 362.783 307.617 1.00 106.02 ? 240 LEU B CD1   1 
ATOM   1832  C  CD2   . LEU A 1 240 ? 393.394 363.564 305.292 1.00 108.11 ? 240 LEU B CD2   1 
ATOM   1833  N  N     . ARG A 1 241 ? 388.443 361.536 306.173 1.00 103.51 ? 241 ARG B N     1 
ATOM   1834  C  CA    . ARG A 1 241 ? 387.496 360.518 306.598 1.00 105.61 ? 241 ARG B CA    1 
ATOM   1835  C  C     . ARG A 1 241 ? 386.312 360.331 305.663 1.00 102.01 ? 241 ARG B C     1 
ATOM   1836  O  O     . ARG A 1 241 ? 385.598 359.333 305.803 1.00 104.83 ? 241 ARG B O     1 
ATOM   1837  C  CB    . ARG A 1 241 ? 386.953 360.868 307.989 1.00 107.88 ? 241 ARG B CB    1 
ATOM   1838  C  CG    . ARG A 1 241 ? 388.009 360.847 309.077 1.00 103.23 ? 241 ARG B CG    1 
ATOM   1839  C  CD    . ARG A 1 241 ? 387.432 361.197 310.437 1.00 102.15 ? 241 ARG B CD    1 
ATOM   1840  N  NE    . ARG A 1 241 ? 386.867 362.547 310.475 1.00 100.79 ? 241 ARG B NE    1 
ATOM   1841  C  CZ    . ARG A 1 241 ? 385.584 362.873 310.614 1.00 100.72 ? 241 ARG B CZ    1 
ATOM   1842  N  NH1   . ARG A 1 241 ? 384.625 361.963 310.697 1.00 102.95 ? 241 ARG B NH1   1 
ATOM   1843  N  NH2   . ARG A 1 241 ? 385.251 364.159 310.674 1.00 107.98 ? 241 ARG B NH2   1 
ATOM   1844  N  N     . PHE A 1 242 ? 386.072 361.257 304.740 1.00 98.19  ? 242 PHE B N     1 
ATOM   1845  C  CA    . PHE A 1 242 ? 384.854 361.280 303.945 1.00 104.97 ? 242 PHE B CA    1 
ATOM   1846  C  C     . PHE A 1 242 ? 385.172 361.887 302.587 1.00 105.37 ? 242 PHE B C     1 
ATOM   1847  O  O     . PHE A 1 242 ? 386.158 362.621 302.452 1.00 107.40 ? 242 PHE B O     1 
ATOM   1848  C  CB    . PHE A 1 242 ? 383.755 362.089 304.652 1.00 107.11 ? 242 PHE B CB    1 
ATOM   1849  C  CG    . PHE A 1 242 ? 383.155 361.404 305.852 1.00 110.34 ? 242 PHE B CG    1 
ATOM   1850  C  CD1   . PHE A 1 242 ? 382.507 360.183 305.732 1.00 110.47 ? 242 PHE B CD1   1 
ATOM   1851  C  CD2   . PHE A 1 242 ? 383.228 361.992 307.102 1.00 110.37 ? 242 PHE B CD2   1 
ATOM   1852  C  CE1   . PHE A 1 242 ? 381.958 359.564 306.833 1.00 110.92 ? 242 PHE B CE1   1 
ATOM   1853  C  CE2   . PHE A 1 242 ? 382.678 361.375 308.204 1.00 109.96 ? 242 PHE B CE2   1 
ATOM   1854  C  CZ    . PHE A 1 242 ? 382.042 360.161 308.070 1.00 109.63 ? 242 PHE B CZ    1 
ATOM   1855  N  N     . PRO A 1 243 ? 384.365 361.603 301.559 1.00 104.54 ? 243 PRO B N     1 
ATOM   1856  C  CA    . PRO A 1 243 ? 384.621 362.216 300.254 1.00 99.99  ? 243 PRO B CA    1 
ATOM   1857  C  C     . PRO A 1 243 ? 384.137 363.655 300.221 1.00 101.92 ? 243 PRO B C     1 
ATOM   1858  O  O     . PRO A 1 243 ? 383.213 364.041 300.940 1.00 105.50 ? 243 PRO B O     1 
ATOM   1859  C  CB    . PRO A 1 243 ? 383.830 361.332 299.286 1.00 102.83 ? 243 PRO B CB    1 
ATOM   1860  C  CG    . PRO A 1 243 ? 382.704 360.787 300.098 1.00 109.24 ? 243 PRO B CG    1 
ATOM   1861  C  CD    . PRO A 1 243 ? 383.051 360.926 301.562 1.00 107.33 ? 243 PRO B CD    1 
ATOM   1862  N  N     . GLY A 1 244 ? 384.772 364.450 299.367 1.00 93.49  ? 244 GLY B N     1 
ATOM   1863  C  CA    . GLY A 1 244 ? 384.447 365.860 299.273 1.00 95.18  ? 244 GLY B CA    1 
ATOM   1864  C  C     . GLY A 1 244 ? 384.836 366.425 297.929 1.00 99.88  ? 244 GLY B C     1 
ATOM   1865  O  O     . GLY A 1 244 ? 385.687 365.876 297.222 1.00 100.60 ? 244 GLY B O     1 
ATOM   1866  N  N     . GLN A 1 245 ? 384.194 367.540 297.582 1.00 103.09 ? 245 GLN B N     1 
ATOM   1867  C  CA    . GLN A 1 245 ? 384.478 368.190 296.307 1.00 95.90  ? 245 GLN B CA    1 
ATOM   1868  C  C     . GLN A 1 245 ? 385.827 368.894 296.336 1.00 99.79  ? 245 GLN B C     1 
ATOM   1869  O  O     . GLN A 1 245 ? 386.516 368.959 295.311 1.00 101.41 ? 245 GLN B O     1 
ATOM   1870  C  CB    . GLN A 1 245 ? 383.362 369.176 295.955 1.00 92.31  ? 245 GLN B CB    1 
ATOM   1871  C  CG    . GLN A 1 245 ? 382.218 368.555 295.160 1.00 100.60 ? 245 GLN B CG    1 
ATOM   1872  C  CD    . GLN A 1 245 ? 381.578 367.377 295.872 1.00 109.57 ? 245 GLN B CD    1 
ATOM   1873  O  OE1   . GLN A 1 245 ? 381.716 367.221 297.085 1.00 110.68 ? 245 GLN B OE1   1 
ATOM   1874  N  NE2   . GLN A 1 245 ? 380.882 366.534 295.117 1.00 110.65 ? 245 GLN B NE2   1 
ATOM   1875  N  N     . LEU A 1 246 ? 386.208 369.434 297.494 1.00 98.21  ? 246 LEU B N     1 
ATOM   1876  C  CA    . LEU A 1 246 ? 387.542 369.986 297.737 1.00 91.54  ? 246 LEU B CA    1 
ATOM   1877  C  C     . LEU A 1 246 ? 388.068 369.346 299.016 1.00 96.68  ? 246 LEU B C     1 
ATOM   1878  O  O     . LEU A 1 246 ? 387.572 369.639 300.108 1.00 101.91 ? 246 LEU B O     1 
ATOM   1879  C  CB    . LEU A 1 246 ? 387.504 371.506 297.860 1.00 92.38  ? 246 LEU B CB    1 
ATOM   1880  C  CG    . LEU A 1 246 ? 387.683 372.342 296.590 1.00 92.49  ? 246 LEU B CG    1 
ATOM   1881  C  CD1   . LEU A 1 246 ? 387.389 373.803 296.887 1.00 95.61  ? 246 LEU B CD1   1 
ATOM   1882  C  CD2   . LEU A 1 246 ? 389.090 372.198 296.019 1.00 92.91  ? 246 LEU B CD2   1 
ATOM   1883  N  N     . ASN A 1 247 ? 389.072 368.482 298.879 1.00 105.76 ? 247 ASN B N     1 
ATOM   1884  C  CA    . ASN A 1 247 ? 389.669 367.793 300.016 1.00 108.82 ? 247 ASN B CA    1 
ATOM   1885  C  C     . ASN A 1 247 ? 390.857 368.599 300.522 1.00 108.15 ? 247 ASN B C     1 
ATOM   1886  O  O     . ASN A 1 247 ? 391.727 368.988 299.737 1.00 109.85 ? 247 ASN B O     1 
ATOM   1887  C  CB    . ASN A 1 247 ? 390.111 366.375 299.644 1.00 106.95 ? 247 ASN B CB    1 
ATOM   1888  C  CG    . ASN A 1 247 ? 388.945 365.431 299.420 1.00 107.86 ? 247 ASN B CG    1 
ATOM   1889  O  OD1   . ASN A 1 247 ? 389.074 364.420 298.732 1.00 107.73 ? 247 ASN B OD1   1 
ATOM   1890  N  ND2   . ASN A 1 247 ? 387.798 365.758 300.005 1.00 110.66 ? 247 ASN B ND2   1 
ATOM   1891  N  N     . ALA A 1 248 ? 390.882 368.848 301.832 1.00 99.91  ? 248 ALA B N     1 
ATOM   1892  C  CA    . ALA A 1 248 ? 391.937 369.618 302.491 1.00 104.63 ? 248 ALA B CA    1 
ATOM   1893  C  C     . ALA A 1 248 ? 392.454 368.809 303.676 1.00 105.98 ? 248 ALA B C     1 
ATOM   1894  O  O     . ALA A 1 248 ? 391.821 368.770 304.735 1.00 105.49 ? 248 ALA B O     1 
ATOM   1895  C  CB    . ALA A 1 248 ? 391.429 370.987 302.929 1.00 103.33 ? 248 ALA B CB    1 
ATOM   1896  N  N     . ASP A 1 249 ? 393.605 368.168 303.493 1.00 118.33 ? 249 ASP B N     1 
ATOM   1897  C  CA    . ASP A 1 249 ? 394.212 367.377 304.552 1.00 111.99 ? 249 ASP B CA    1 
ATOM   1898  C  C     . ASP A 1 249 ? 394.910 368.291 305.559 1.00 111.30 ? 249 ASP B C     1 
ATOM   1899  O  O     . ASP A 1 249 ? 394.969 369.514 305.404 1.00 116.02 ? 249 ASP B O     1 
ATOM   1900  C  CB    . ASP A 1 249 ? 395.189 366.361 303.963 1.00 111.40 ? 249 ASP B CB    1 
ATOM   1901  C  CG    . ASP A 1 249 ? 396.361 367.013 303.270 1.00 117.07 ? 249 ASP B CG    1 
ATOM   1902  O  OD1   . ASP A 1 249 ? 397.374 367.278 303.947 1.00 121.63 ? 249 ASP B OD1   1 
ATOM   1903  O  OD2   . ASP A 1 249 ? 396.272 367.256 302.048 1.00 118.37 ? 249 ASP B OD2   1 
ATOM   1904  N  N     . LEU A 1 250 ? 395.447 367.675 306.614 1.00 101.66 ? 250 LEU B N     1 
ATOM   1905  C  CA    . LEU A 1 250 ? 396.048 368.450 307.698 1.00 102.24 ? 250 LEU B CA    1 
ATOM   1906  C  C     . LEU A 1 250 ? 397.334 369.130 307.247 1.00 101.11 ? 250 LEU B C     1 
ATOM   1907  O  O     . LEU A 1 250 ? 397.615 370.266 307.648 1.00 100.65 ? 250 LEU B O     1 
ATOM   1908  C  CB    . LEU A 1 250 ? 396.311 367.553 308.912 1.00 100.28 ? 250 LEU B CB    1 
ATOM   1909  C  CG    . LEU A 1 250 ? 395.373 367.783 310.099 1.00 102.07 ? 250 LEU B CG    1 
ATOM   1910  C  CD1   . LEU A 1 250 ? 393.998 367.210 309.796 1.00 104.35 ? 250 LEU B CD1   1 
ATOM   1911  C  CD2   . LEU A 1 250 ? 395.935 367.150 311.360 1.00 99.51  ? 250 LEU B CD2   1 
ATOM   1912  N  N     . ARG A 1 251 ? 398.129 368.460 306.413 1.00 100.13 ? 251 ARG B N     1 
ATOM   1913  C  CA    . ARG A 1 251 ? 399.323 369.103 305.879 1.00 95.69  ? 251 ARG B CA    1 
ATOM   1914  C  C     . ARG A 1 251 ? 398.957 370.262 304.961 1.00 94.88  ? 251 ARG B C     1 
ATOM   1915  O  O     . ARG A 1 251 ? 399.646 371.290 304.951 1.00 100.11 ? 251 ARG B O     1 
ATOM   1916  C  CB    . ARG A 1 251 ? 400.181 368.085 305.133 1.00 98.30  ? 251 ARG B CB    1 
ATOM   1917  C  CG    . ARG A 1 251 ? 401.619 368.519 304.932 1.00 94.52  ? 251 ARG B CG    1 
ATOM   1918  C  CD    . ARG A 1 251 ? 402.408 367.462 304.183 1.00 97.42  ? 251 ARG B CD    1 
ATOM   1919  N  NE    . ARG A 1 251 ? 402.678 366.291 305.011 1.00 104.43 ? 251 ARG B NE    1 
ATOM   1920  C  CZ    . ARG A 1 251 ? 403.632 366.198 305.931 1.00 106.98 ? 251 ARG B CZ    1 
ATOM   1921  N  NH1   . ARG A 1 251 ? 404.451 367.206 306.198 1.00 106.28 ? 251 ARG B NH1   1 
ATOM   1922  N  NH2   . ARG A 1 251 ? 403.769 365.061 306.606 1.00 107.22 ? 251 ARG B NH2   1 
ATOM   1923  N  N     . LYS A 1 252 ? 397.878 370.111 304.187 1.00 95.54  ? 252 LYS B N     1 
ATOM   1924  C  CA    . LYS A 1 252 ? 397.396 371.213 303.363 1.00 96.47  ? 252 LYS B CA    1 
ATOM   1925  C  C     . LYS A 1 252 ? 396.975 372.388 304.230 1.00 94.59  ? 252 LYS B C     1 
ATOM   1926  O  O     . LYS A 1 252 ? 397.251 373.549 303.900 1.00 96.49  ? 252 LYS B O     1 
ATOM   1927  C  CB    . LYS A 1 252 ? 396.217 370.757 302.500 1.00 97.67  ? 252 LYS B CB    1 
ATOM   1928  C  CG    . LYS A 1 252 ? 396.093 371.506 301.178 1.00 98.02  ? 252 LYS B CG    1 
ATOM   1929  C  CD    . LYS A 1 252 ? 395.220 370.806 300.148 1.00 101.72 ? 252 LYS B CD    1 
ATOM   1930  C  CE    . LYS A 1 252 ? 395.911 369.626 299.484 1.00 108.75 ? 252 LYS B CE    1 
ATOM   1931  N  NZ    . LYS A 1 252 ? 394.941 368.802 298.713 1.00 106.45 ? 252 LYS B NZ    1 
ATOM   1932  N  N     . LEU A 1 253 ? 396.301 372.099 305.345 1.00 107.10 ? 253 LEU B N     1 
ATOM   1933  C  CA    . LEU A 1 253 ? 395.922 373.153 306.274 1.00 110.08 ? 253 LEU B CA    1 
ATOM   1934  C  C     . LEU A 1 253 ? 397.151 373.838 306.848 1.00 108.57 ? 253 LEU B C     1 
ATOM   1935  O  O     . LEU A 1 253 ? 397.165 375.060 306.995 1.00 105.31 ? 253 LEU B O     1 
ATOM   1936  C  CB    . LEU A 1 253 ? 395.059 372.580 307.403 1.00 108.09 ? 253 LEU B CB    1 
ATOM   1937  C  CG    . LEU A 1 253 ? 393.574 372.225 307.200 1.00 107.84 ? 253 LEU B CG    1 
ATOM   1938  C  CD1   . LEU A 1 253 ? 392.879 372.187 308.553 1.00 109.16 ? 253 LEU B CD1   1 
ATOM   1939  C  CD2   . LEU A 1 253 ? 392.815 373.164 306.266 1.00 105.71 ? 253 LEU B CD2   1 
ATOM   1940  N  N     . ALA A 1 254 ? 398.194 373.070 307.171 1.00 114.90 ? 254 ALA B N     1 
ATOM   1941  C  CA    . ALA A 1 254 ? 399.426 373.671 307.680 1.00 110.33 ? 254 ALA B CA    1 
ATOM   1942  C  C     . ALA A 1 254 ? 400.050 374.609 306.655 1.00 105.46 ? 254 ALA B C     1 
ATOM   1943  O  O     . ALA A 1 254 ? 400.430 375.742 306.984 1.00 106.94 ? 254 ALA B O     1 
ATOM   1944  C  CB    . ALA A 1 254 ? 400.428 372.581 308.062 1.00 117.88 ? 254 ALA B CB    1 
ATOM   1945  N  N     . VAL A 1 255 ? 400.137 374.157 305.401 1.00 94.87  ? 255 VAL B N     1 
ATOM   1946  C  CA    . VAL A 1 255 ? 400.763 374.958 304.353 1.00 91.66  ? 255 VAL B CA    1 
ATOM   1947  C  C     . VAL A 1 255 ? 399.957 376.226 304.096 1.00 92.40  ? 255 VAL B C     1 
ATOM   1948  O  O     . VAL A 1 255 ? 400.525 377.295 303.847 1.00 92.75  ? 255 VAL B O     1 
ATOM   1949  C  CB    . VAL A 1 255 ? 400.931 374.115 303.073 1.00 87.68  ? 255 VAL B CB    1 
ATOM   1950  C  CG1   . VAL A 1 255 ? 401.321 374.988 301.881 1.00 92.07  ? 255 VAL B CG1   1 
ATOM   1951  C  CG2   . VAL A 1 255 ? 401.974 373.021 303.287 1.00 91.89  ? 255 VAL B CG2   1 
ATOM   1952  N  N     . ASN A 1 256 ? 398.628 376.131 304.149 1.00 95.83  ? 256 ASN B N     1 
ATOM   1953  C  CA    . ASN A 1 256 ? 397.786 377.302 303.932 1.00 87.90  ? 256 ASN B CA    1 
ATOM   1954  C  C     . ASN A 1 256 ? 397.716 378.228 305.141 1.00 94.80  ? 256 ASN B C     1 
ATOM   1955  O  O     . ASN A 1 256 ? 397.464 379.424 304.966 1.00 97.80  ? 256 ASN B O     1 
ATOM   1956  C  CB    . ASN A 1 256 ? 396.370 376.865 303.552 1.00 91.09  ? 256 ASN B CB    1 
ATOM   1957  C  CG    . ASN A 1 256 ? 396.237 376.552 302.078 1.00 96.20  ? 256 ASN B CG    1 
ATOM   1958  O  OD1   . ASN A 1 256 ? 396.051 377.448 301.257 1.00 96.27  ? 256 ASN B OD1   1 
ATOM   1959  N  ND2   . ASN A 1 256 ? 396.339 375.275 301.734 1.00 103.75 ? 256 ASN B ND2   1 
ATOM   1960  N  N     . MET A 1 257 ? 397.943 377.714 306.353 1.00 104.98 ? 257 MET B N     1 
ATOM   1961  C  CA    . MET A 1 257 ? 397.723 378.470 307.579 1.00 98.11  ? 257 MET B CA    1 
ATOM   1962  C  C     . MET A 1 257 ? 398.969 379.157 308.102 1.00 99.98  ? 257 MET B C     1 
ATOM   1963  O  O     . MET A 1 257 ? 398.857 380.247 308.668 1.00 98.39  ? 257 MET B O     1 
ATOM   1964  C  CB    . MET A 1 257 ? 397.219 377.549 308.695 1.00 101.18 ? 257 MET B CB    1 
ATOM   1965  C  CG    . MET A 1 257 ? 395.746 377.140 308.687 1.00 105.35 ? 257 MET B CG    1 
ATOM   1966  S  SD    . MET A 1 257 ? 394.547 378.449 308.998 1.00 119.47 ? 257 MET B SD    1 
ATOM   1967  C  CE    . MET A 1 257 ? 394.286 379.136 307.369 1.00 96.14  ? 257 MET B CE    1 
ATOM   1968  N  N     . VAL A 1 258 ? 400.137 378.537 307.959 1.00 103.87 ? 258 VAL B N     1 
ATOM   1969  C  CA    . VAL A 1 258 ? 401.352 378.992 308.633 1.00 93.64  ? 258 VAL B CA    1 
ATOM   1970  C  C     . VAL A 1 258 ? 402.199 379.797 307.651 1.00 96.36  ? 258 VAL B C     1 
ATOM   1971  O  O     . VAL A 1 258 ? 402.942 379.192 306.864 1.00 104.35 ? 258 VAL B O     1 
ATOM   1972  C  CB    . VAL A 1 258 ? 402.139 377.797 309.198 1.00 101.63 ? 258 VAL B CB    1 
ATOM   1973  C  CG1   . VAL A 1 258 ? 403.361 378.270 309.989 1.00 105.94 ? 258 VAL B CG1   1 
ATOM   1974  C  CG2   . VAL A 1 258 ? 401.227 376.924 310.066 1.00 102.98 ? 258 VAL B CG2   1 
ATOM   1975  N  N     . PRO A 1 259 ? 402.137 381.150 307.635 1.00 92.90  ? 259 PRO B N     1 
ATOM   1976  C  CA    . PRO A 1 259 ? 403.061 381.887 306.763 1.00 99.26  ? 259 PRO B CA    1 
ATOM   1977  C  C     . PRO A 1 259 ? 404.510 381.737 307.194 1.00 94.53  ? 259 PRO B C     1 
ATOM   1978  O  O     . PRO A 1 259 ? 405.356 381.315 306.399 1.00 92.76  ? 259 PRO B O     1 
ATOM   1979  C  CB    . PRO A 1 259 ? 402.578 383.339 306.876 1.00 96.90  ? 259 PRO B CB    1 
ATOM   1980  C  CG    . PRO A 1 259 ? 401.829 383.400 308.139 1.00 96.44  ? 259 PRO B CG    1 
ATOM   1981  C  CD    . PRO A 1 259 ? 401.178 382.067 308.277 1.00 94.09  ? 259 PRO B CD    1 
ATOM   1982  N  N     . PHE A 1 260 ? 404.792 382.053 308.456 1.00 82.63  ? 260 PHE B N     1 
ATOM   1983  C  CA    . PHE A 1 260 ? 406.112 381.974 309.053 1.00 79.38  ? 260 PHE B CA    1 
ATOM   1984  C  C     . PHE A 1 260 ? 406.111 380.898 310.130 1.00 89.20  ? 260 PHE B C     1 
ATOM   1985  O  O     . PHE A 1 260 ? 405.059 380.619 310.712 1.00 95.28  ? 260 PHE B O     1 
ATOM   1986  C  CB    . PHE A 1 260 ? 406.516 383.326 309.650 1.00 87.79  ? 260 PHE B CB    1 
ATOM   1987  C  CG    . PHE A 1 260 ? 406.406 384.459 308.675 1.00 90.56  ? 260 PHE B CG    1 
ATOM   1988  C  CD1   . PHE A 1 260 ? 407.440 384.738 307.800 1.00 91.46  ? 260 PHE B CD1   1 
ATOM   1989  C  CD2   . PHE A 1 260 ? 405.261 385.229 308.615 1.00 87.96  ? 260 PHE B CD2   1 
ATOM   1990  C  CE1   . PHE A 1 260 ? 407.339 385.773 306.895 1.00 92.81  ? 260 PHE B CE1   1 
ATOM   1991  C  CE2   . PHE A 1 260 ? 405.152 386.260 307.707 1.00 90.54  ? 260 PHE B CE2   1 
ATOM   1992  C  CZ    . PHE A 1 260 ? 406.193 386.535 306.849 1.00 93.05  ? 260 PHE B CZ    1 
ATOM   1993  N  N     . PRO A 1 261 ? 407.265 380.282 310.428 1.00 105.30 ? 261 PRO B N     1 
ATOM   1994  C  CA    . PRO A 1 261 ? 407.242 379.001 311.160 1.00 105.99 ? 261 PRO B CA    1 
ATOM   1995  C  C     . PRO A 1 261 ? 406.697 379.078 312.577 1.00 111.36 ? 261 PRO B C     1 
ATOM   1996  O  O     . PRO A 1 261 ? 406.352 378.029 313.134 1.00 113.63 ? 261 PRO B O     1 
ATOM   1997  C  CB    . PRO A 1 261 ? 408.718 378.571 311.167 1.00 105.28 ? 261 PRO B CB    1 
ATOM   1998  C  CG    . PRO A 1 261 ? 409.397 379.443 310.170 1.00 106.66 ? 261 PRO B CG    1 
ATOM   1999  C  CD    . PRO A 1 261 ? 408.652 380.726 310.201 1.00 107.14 ? 261 PRO B CD    1 
ATOM   2000  N  N     . ARG A 1 262 ? 406.601 380.271 313.170 1.00 111.56 ? 262 ARG B N     1 
ATOM   2001  C  CA    . ARG A 1 262 ? 406.186 380.438 314.558 1.00 110.87 ? 262 ARG B CA    1 
ATOM   2002  C  C     . ARG A 1 262 ? 404.756 380.944 314.713 1.00 105.83 ? 262 ARG B C     1 
ATOM   2003  O  O     . ARG A 1 262 ? 404.201 380.833 315.812 1.00 108.24 ? 262 ARG B O     1 
ATOM   2004  C  CB    . ARG A 1 262 ? 407.145 381.395 315.274 1.00 110.63 ? 262 ARG B CB    1 
ATOM   2005  C  CG    . ARG A 1 262 ? 408.619 381.094 315.015 1.00 109.53 ? 262 ARG B CG    1 
ATOM   2006  C  CD    . ARG A 1 262 ? 409.464 381.282 316.255 1.00 110.70 ? 262 ARG B CD    1 
ATOM   2007  N  NE    . ARG A 1 262 ? 409.267 382.586 316.878 1.00 110.75 ? 262 ARG B NE    1 
ATOM   2008  C  CZ    . ARG A 1 262 ? 409.640 382.909 318.111 1.00 115.14 ? 262 ARG B CZ    1 
ATOM   2009  N  NH1   . ARG A 1 262 ? 410.254 382.045 318.908 1.00 115.05 ? 262 ARG B NH1   1 
ATOM   2010  N  NH2   . ARG A 1 262 ? 409.395 384.136 318.560 1.00 119.68 ? 262 ARG B NH2   1 
ATOM   2011  N  N     . LEU A 1 263 ? 404.146 381.484 313.655 1.00 94.60  ? 263 LEU B N     1 
ATOM   2012  C  CA    . LEU A 1 263 ? 402.768 381.979 313.708 1.00 95.00  ? 263 LEU B CA    1 
ATOM   2013  C  C     . LEU A 1 263 ? 401.811 380.871 313.265 1.00 99.92  ? 263 LEU B C     1 
ATOM   2014  O  O     . LEU A 1 263 ? 401.284 380.860 312.151 1.00 109.83 ? 263 LEU B O     1 
ATOM   2015  C  CB    . LEU A 1 263 ? 402.619 383.223 312.841 1.00 96.80  ? 263 LEU B CB    1 
ATOM   2016  C  CG    . LEU A 1 263 ? 403.653 384.338 313.014 1.00 97.17  ? 263 LEU B CG    1 
ATOM   2017  C  CD1   . LEU A 1 263 ? 403.226 385.548 312.206 1.00 98.32  ? 263 LEU B CD1   1 
ATOM   2018  C  CD2   . LEU A 1 263 ? 403.863 384.717 314.471 1.00 96.90  ? 263 LEU B CD2   1 
ATOM   2019  N  N     . HIS A 1 264 ? 401.591 379.923 314.183 1.00 100.62 ? 264 HIS B N     1 
ATOM   2020  C  CA    . HIS A 1 264 ? 400.731 378.764 313.960 1.00 97.71  ? 264 HIS B CA    1 
ATOM   2021  C  C     . HIS A 1 264 ? 399.670 378.639 315.052 1.00 103.06 ? 264 HIS B C     1 
ATOM   2022  O  O     . HIS A 1 264 ? 399.254 377.531 315.397 1.00 112.40 ? 264 HIS B O     1 
ATOM   2023  C  CB    . HIS A 1 264 ? 401.569 377.488 313.860 1.00 98.62  ? 264 HIS B CB    1 
ATOM   2024  C  CG    . HIS A 1 264 ? 402.535 377.299 314.989 1.00 101.68 ? 264 HIS B CG    1 
ATOM   2025  N  ND1   . HIS A 1 264 ? 402.139 377.178 316.303 1.00 102.81 ? 264 HIS B ND1   1 
ATOM   2026  C  CD2   . HIS A 1 264 ? 403.885 377.206 314.995 1.00 102.78 ? 264 HIS B CD2   1 
ATOM   2027  C  CE1   . HIS A 1 264 ? 403.203 377.022 317.070 1.00 102.81 ? 264 HIS B CE1   1 
ATOM   2028  N  NE2   . HIS A 1 264 ? 404.276 377.034 316.300 1.00 102.76 ? 264 HIS B NE2   1 
ATOM   2029  N  N     . PHE A 1 265 ? 399.220 379.770 315.593 1.00 94.54  ? 265 PHE B N     1 
ATOM   2030  C  CA    . PHE A 1 265 ? 398.251 379.820 316.682 1.00 93.96  ? 265 PHE B CA    1 
ATOM   2031  C  C     . PHE A 1 265 ? 396.939 380.343 316.118 1.00 95.96  ? 265 PHE B C     1 
ATOM   2032  O  O     . PHE A 1 265 ? 396.859 381.511 315.723 1.00 100.62 ? 265 PHE B O     1 
ATOM   2033  C  CB    . PHE A 1 265 ? 398.745 380.720 317.812 1.00 97.72  ? 265 PHE B CB    1 
ATOM   2034  C  CG    . PHE A 1 265 ? 399.999 380.227 318.475 1.00 102.78 ? 265 PHE B CG    1 
ATOM   2035  C  CD1   . PHE A 1 265 ? 401.243 380.502 317.933 1.00 104.40 ? 265 PHE B CD1   1 
ATOM   2036  C  CD2   . PHE A 1 265 ? 399.934 379.473 319.629 1.00 96.52  ? 265 PHE B CD2   1 
ATOM   2037  C  CE1   . PHE A 1 265 ? 402.394 380.045 318.538 1.00 104.02 ? 265 PHE B CE1   1 
ATOM   2038  C  CE2   . PHE A 1 265 ? 401.081 379.013 320.239 1.00 96.38  ? 265 PHE B CE2   1 
ATOM   2039  C  CZ    . PHE A 1 265 ? 402.313 379.299 319.692 1.00 98.88  ? 265 PHE B CZ    1 
ATOM   2040  N  N     . PHE A 1 266 ? 395.915 379.490 316.102 1.00 99.30  ? 266 PHE B N     1 
ATOM   2041  C  CA    . PHE A 1 266 ? 394.676 379.755 315.385 1.00 101.37 ? 266 PHE B CA    1 
ATOM   2042  C  C     . PHE A 1 266 ? 393.507 379.880 316.348 1.00 98.15  ? 266 PHE B C     1 
ATOM   2043  O  O     . PHE A 1 266 ? 393.509 379.320 317.446 1.00 103.29 ? 266 PHE B O     1 
ATOM   2044  C  CB    . PHE A 1 266 ? 394.387 378.650 314.370 1.00 100.98 ? 266 PHE B CB    1 
ATOM   2045  C  CG    . PHE A 1 266 ? 395.597 378.206 313.625 1.00 101.04 ? 266 PHE B CG    1 
ATOM   2046  C  CD1   . PHE A 1 266 ? 396.381 379.123 312.953 1.00 98.36  ? 266 PHE B CD1   1 
ATOM   2047  C  CD2   . PHE A 1 266 ? 395.968 376.879 313.615 1.00 103.92 ? 266 PHE B CD2   1 
ATOM   2048  C  CE1   . PHE A 1 266 ? 397.503 378.723 312.279 1.00 101.65 ? 266 PHE B CE1   1 
ATOM   2049  C  CE2   . PHE A 1 266 ? 397.090 376.474 312.938 1.00 103.02 ? 266 PHE B CE2   1 
ATOM   2050  C  CZ    . PHE A 1 266 ? 397.860 377.394 312.270 1.00 105.58 ? 266 PHE B CZ    1 
ATOM   2051  N  N     . MET A 1 267 ? 392.509 380.641 315.907 1.00 108.58 ? 267 MET B N     1 
ATOM   2052  C  CA    . MET A 1 267 ? 391.249 380.839 316.612 1.00 110.21 ? 267 MET B CA    1 
ATOM   2053  C  C     . MET A 1 267 ? 390.182 380.044 315.861 1.00 115.27 ? 267 MET B C     1 
ATOM   2054  O  O     . MET A 1 267 ? 389.840 380.407 314.724 1.00 125.36 ? 267 MET B O     1 
ATOM   2055  C  CB    . MET A 1 267 ? 390.894 382.327 316.649 1.00 113.90 ? 267 MET B CB    1 
ATOM   2056  C  CG    . MET A 1 267 ? 391.869 383.148 317.505 1.00 124.92 ? 267 MET B CG    1 
ATOM   2057  S  SD    . MET A 1 267 ? 391.727 384.956 317.530 1.00 144.17 ? 267 MET B SD    1 
ATOM   2058  C  CE    . MET A 1 267 ? 390.526 385.325 316.256 1.00 118.86 ? 267 MET B CE    1 
ATOM   2059  N  N     . PRO A 1 268 ? 389.667 378.935 316.399 1.00 106.46 ? 268 PRO B N     1 
ATOM   2060  C  CA    . PRO A 1 268 ? 388.671 378.157 315.657 1.00 105.77 ? 268 PRO B CA    1 
ATOM   2061  C  C     . PRO A 1 268 ? 387.256 378.685 315.863 1.00 106.08 ? 268 PRO B C     1 
ATOM   2062  O  O     . PRO A 1 268 ? 387.001 379.593 316.652 1.00 111.02 ? 268 PRO B O     1 
ATOM   2063  C  CB    . PRO A 1 268 ? 388.825 376.745 316.221 1.00 103.86 ? 268 PRO B CB    1 
ATOM   2064  C  CG    . PRO A 1 268 ? 389.335 376.926 317.564 1.00 110.03 ? 268 PRO B CG    1 
ATOM   2065  C  CD    . PRO A 1 268 ? 390.030 378.248 317.653 1.00 112.00 ? 268 PRO B CD    1 
ATOM   2066  N  N     . GLY A 1 269 ? 386.335 378.106 315.093 1.00 108.30 ? 269 GLY B N     1 
ATOM   2067  C  CA    . GLY A 1 269 ? 384.931 378.459 315.172 1.00 104.63 ? 269 GLY B CA    1 
ATOM   2068  C  C     . GLY A 1 269 ? 384.087 377.401 314.495 1.00 107.15 ? 269 GLY B C     1 
ATOM   2069  O  O     . GLY A 1 269 ? 384.600 376.518 313.806 1.00 113.83 ? 269 GLY B O     1 
ATOM   2070  N  N     . PHE A 1 270 ? 382.772 377.525 314.664 1.00 96.21  ? 270 PHE B N     1 
ATOM   2071  C  CA    . PHE A 1 270 ? 381.842 376.538 314.134 1.00 94.51  ? 270 PHE B CA    1 
ATOM   2072  C  C     . PHE A 1 270 ? 380.497 377.201 313.886 1.00 99.81  ? 270 PHE B C     1 
ATOM   2073  O  O     . PHE A 1 270 ? 380.119 378.144 314.585 1.00 103.58 ? 270 PHE B O     1 
ATOM   2074  C  CB    . PHE A 1 270 ? 381.687 375.359 315.102 1.00 93.32  ? 270 PHE B CB    1 
ATOM   2075  C  CG    . PHE A 1 270 ? 380.850 374.232 314.567 1.00 95.71  ? 270 PHE B CG    1 
ATOM   2076  C  CD1   . PHE A 1 270 ? 381.414 373.253 313.771 1.00 99.74  ? 270 PHE B CD1   1 
ATOM   2077  C  CD2   . PHE A 1 270 ? 379.500 374.153 314.862 1.00 98.94  ? 270 PHE B CD2   1 
ATOM   2078  C  CE1   . PHE A 1 270 ? 380.648 372.217 313.278 1.00 99.53  ? 270 PHE B CE1   1 
ATOM   2079  C  CE2   . PHE A 1 270 ? 378.730 373.120 314.371 1.00 99.75  ? 270 PHE B CE2   1 
ATOM   2080  C  CZ    . PHE A 1 270 ? 379.304 372.151 313.579 1.00 98.65  ? 270 PHE B CZ    1 
ATOM   2081  N  N     . ALA A 1 271 ? 379.783 376.703 312.875 1.00 107.53 ? 271 ALA B N     1 
ATOM   2082  C  CA    . ALA A 1 271 ? 378.394 377.085 312.657 1.00 107.37 ? 271 ALA B CA    1 
ATOM   2083  C  C     . ALA A 1 271 ? 377.695 375.944 311.934 1.00 108.54 ? 271 ALA B C     1 
ATOM   2084  O  O     . ALA A 1 271 ? 378.365 375.142 311.278 1.00 113.33 ? 271 ALA B O     1 
ATOM   2085  C  CB    . ALA A 1 271 ? 378.293 378.382 311.843 1.00 112.10 ? 271 ALA B CB    1 
ATOM   2086  N  N     . PRO A 1 272 ? 376.358 375.821 312.044 1.00 98.59  ? 272 PRO B N     1 
ATOM   2087  C  CA    . PRO A 1 272 ? 375.409 376.592 312.859 1.00 98.79  ? 272 PRO B CA    1 
ATOM   2088  C  C     . PRO A 1 272 ? 375.468 376.180 314.324 1.00 104.41 ? 272 PRO B C     1 
ATOM   2089  O  O     . PRO A 1 272 ? 375.859 375.057 314.630 1.00 105.56 ? 272 PRO B O     1 
ATOM   2090  C  CB    . PRO A 1 272 ? 374.060 376.261 312.214 1.00 99.74  ? 272 PRO B CB    1 
ATOM   2091  C  CG    . PRO A 1 272 ? 374.230 374.869 311.715 1.00 94.94  ? 272 PRO B CG    1 
ATOM   2092  C  CD    . PRO A 1 272 ? 375.669 374.772 311.271 1.00 100.93 ? 272 PRO B CD    1 
ATOM   2093  N  N     . LEU A 1 273 ? 375.096 377.084 315.239 1.00 114.56 ? 273 LEU B N     1 
ATOM   2094  C  CA    . LEU A 1 273 ? 375.019 376.797 316.668 1.00 113.46 ? 273 LEU B CA    1 
ATOM   2095  C  C     . LEU A 1 273 ? 373.716 377.332 317.251 1.00 114.46 ? 273 LEU B C     1 
ATOM   2096  O  O     . LEU A 1 273 ? 373.671 377.740 318.417 1.00 121.80 ? 273 LEU B O     1 
ATOM   2097  C  CB    . LEU A 1 273 ? 376.222 377.388 317.413 1.00 115.23 ? 273 LEU B CB    1 
ATOM   2098  C  CG    . LEU A 1 273 ? 377.589 376.795 317.067 1.00 118.39 ? 273 LEU B CG    1 
ATOM   2099  C  CD1   . LEU A 1 273 ? 378.700 377.764 317.439 1.00 118.76 ? 273 LEU B CD1   1 
ATOM   2100  C  CD2   . LEU A 1 273 ? 377.792 375.455 317.758 1.00 112.05 ? 273 LEU B CD2   1 
ATOM   2101  N  N     . THR A 1 274 ? 372.645 377.321 316.463 1.00 129.12 ? 274 THR B N     1 
ATOM   2102  C  CA    . THR A 1 274 ? 371.388 377.907 316.895 1.00 136.02 ? 274 THR B CA    1 
ATOM   2103  C  C     . THR A 1 274 ? 370.753 377.066 318.001 1.00 135.49 ? 274 THR B C     1 
ATOM   2104  O  O     . THR A 1 274 ? 371.126 375.917 318.249 1.00 133.43 ? 274 THR B O     1 
ATOM   2105  C  CB    . THR A 1 274 ? 370.426 378.040 315.716 1.00 136.60 ? 274 THR B CB    1 
ATOM   2106  O  OG1   . THR A 1 274 ? 370.128 376.741 315.188 1.00 135.29 ? 274 THR B OG1   1 
ATOM   2107  C  CG2   . THR A 1 274 ? 371.031 378.912 314.623 1.00 132.40 ? 274 THR B CG2   1 
ATOM   2108  N  N     . SER A 1 275 ? 369.776 377.668 318.673 1.00 153.86 ? 275 SER B N     1 
ATOM   2109  C  CA    . SER A 1 275 ? 369.104 377.044 319.803 1.00 153.29 ? 275 SER B CA    1 
ATOM   2110  C  C     . SER A 1 275 ? 368.031 376.086 319.294 1.00 157.92 ? 275 SER B C     1 
ATOM   2111  O  O     . SER A 1 275 ? 367.941 375.792 318.101 1.00 161.85 ? 275 SER B O     1 
ATOM   2112  C  CB    . SER A 1 275 ? 368.513 378.116 320.709 1.00 155.08 ? 275 SER B CB    1 
ATOM   2113  O  OG    . SER A 1 275 ? 367.366 378.702 320.119 1.00 156.24 ? 275 SER B OG    1 
ATOM   2114  N  N     . ARG A 1 276 ? 367.197 375.580 320.205 1.00 155.83 ? 276 ARG B N     1 
ATOM   2115  C  CA    . ARG A 1 276 ? 366.102 374.707 319.794 1.00 155.98 ? 276 ARG B CA    1 
ATOM   2116  C  C     . ARG A 1 276 ? 365.042 375.484 319.021 1.00 156.57 ? 276 ARG B C     1 
ATOM   2117  O  O     . ARG A 1 276 ? 364.635 375.078 317.925 1.00 157.74 ? 276 ARG B O     1 
ATOM   2118  C  CB    . ARG A 1 276 ? 365.486 374.034 321.021 1.00 152.70 ? 276 ARG B CB    1 
ATOM   2119  N  N     . GLY A 1 277 ? 364.582 376.606 319.578 1.00 159.67 ? 277 GLY B N     1 
ATOM   2120  C  CA    . GLY A 1 277 ? 363.534 377.372 318.922 1.00 162.68 ? 277 GLY B CA    1 
ATOM   2121  C  C     . GLY A 1 277 ? 363.998 378.053 317.649 1.00 167.48 ? 277 GLY B C     1 
ATOM   2122  O  O     . GLY A 1 277 ? 363.252 378.128 316.669 1.00 170.46 ? 277 GLY B O     1 
ATOM   2123  N  N     . SER A 1 278 ? 365.234 378.557 317.643 1.00 178.31 ? 278 SER B N     1 
ATOM   2124  C  CA    . SER A 1 278 ? 365.712 379.375 316.533 1.00 179.68 ? 278 SER B CA    1 
ATOM   2125  C  C     . SER A 1 278 ? 365.861 378.593 315.231 1.00 180.06 ? 278 SER B C     1 
ATOM   2126  O  O     . SER A 1 278 ? 365.928 379.212 314.163 1.00 180.76 ? 278 SER B O     1 
ATOM   2127  C  CB    . SER A 1 278 ? 367.049 380.018 316.902 1.00 178.32 ? 278 SER B CB    1 
ATOM   2128  O  OG    . SER A 1 278 ? 366.895 380.921 317.983 1.00 178.14 ? 278 SER B OG    1 
ATOM   2129  N  N     . GLN A 1 279 ? 365.932 377.259 315.292 1.00 174.71 ? 279 GLN B N     1 
ATOM   2130  C  CA    . GLN A 1 279 ? 366.016 376.464 314.070 1.00 172.81 ? 279 GLN B CA    1 
ATOM   2131  C  C     . GLN A 1 279 ? 364.784 376.638 313.195 1.00 172.16 ? 279 GLN B C     1 
ATOM   2132  O  O     . GLN A 1 279 ? 364.891 376.621 311.964 1.00 172.52 ? 279 GLN B O     1 
ATOM   2133  C  CB    . GLN A 1 279 ? 366.209 374.988 314.420 1.00 172.04 ? 279 GLN B CB    1 
ATOM   2134  C  CG    . GLN A 1 279 ? 367.586 374.667 314.974 1.00 174.33 ? 279 GLN B CG    1 
ATOM   2135  C  CD    . GLN A 1 279 ? 367.688 373.265 315.548 1.00 173.90 ? 279 GLN B CD    1 
ATOM   2136  O  OE1   . GLN A 1 279 ? 366.688 372.668 315.950 1.00 172.01 ? 279 GLN B OE1   1 
ATOM   2137  N  NE2   . GLN A 1 279 ? 368.904 372.735 315.598 1.00 172.49 ? 279 GLN B NE2   1 
ATOM   2138  N  N     . GLN A 1 280 ? 363.610 376.809 313.804 1.00 169.55 ? 280 GLN B N     1 
ATOM   2139  C  CA    . GLN A 1 280 ? 362.395 376.969 313.012 1.00 170.21 ? 280 GLN B CA    1 
ATOM   2140  C  C     . GLN A 1 280 ? 362.376 378.319 312.307 1.00 171.45 ? 280 GLN B C     1 
ATOM   2141  O  O     . GLN A 1 280 ? 361.974 378.411 311.141 1.00 173.13 ? 280 GLN B O     1 
ATOM   2142  C  CB    . GLN A 1 280 ? 361.153 376.812 313.894 1.00 170.21 ? 280 GLN B CB    1 
ATOM   2143  C  CG    . GLN A 1 280 ? 361.187 375.643 314.882 1.00 170.99 ? 280 GLN B CG    1 
ATOM   2144  C  CD    . GLN A 1 280 ? 361.670 374.347 314.257 1.00 171.31 ? 280 GLN B CD    1 
ATOM   2145  O  OE1   . GLN A 1 280 ? 361.297 374.008 313.134 1.00 171.32 ? 280 GLN B OE1   1 
ATOM   2146  N  NE2   . GLN A 1 280 ? 362.509 373.616 314.983 1.00 169.10 ? 280 GLN B NE2   1 
ATOM   2147  N  N     . TYR A 1 281 ? 362.808 379.377 312.995 1.00 179.95 ? 281 TYR B N     1 
ATOM   2148  C  CA    . TYR A 1 281 ? 362.764 380.714 312.414 1.00 181.17 ? 281 TYR B CA    1 
ATOM   2149  C  C     . TYR A 1 281 ? 363.870 380.927 311.388 1.00 179.61 ? 281 TYR B C     1 
ATOM   2150  O  O     . TYR A 1 281 ? 363.633 381.535 310.338 1.00 181.33 ? 281 TYR B O     1 
ATOM   2151  C  CB    . TYR A 1 281 ? 362.864 381.767 313.517 1.00 180.03 ? 281 TYR B CB    1 
ATOM   2152  C  CG    . TYR A 1 281 ? 361.783 381.652 314.564 1.00 181.12 ? 281 TYR B CG    1 
ATOM   2153  C  CD1   . TYR A 1 281 ? 360.540 382.237 314.371 1.00 181.29 ? 281 TYR B CD1   1 
ATOM   2154  C  CD2   . TYR A 1 281 ? 362.006 380.959 315.745 1.00 181.55 ? 281 TYR B CD2   1 
ATOM   2155  C  CE1   . TYR A 1 281 ? 359.548 382.134 315.325 1.00 180.99 ? 281 TYR B CE1   1 
ATOM   2156  C  CE2   . TYR A 1 281 ? 361.020 380.851 316.705 1.00 180.94 ? 281 TYR B CE2   1 
ATOM   2157  C  CZ    . TYR A 1 281 ? 359.793 381.440 316.490 1.00 181.19 ? 281 TYR B CZ    1 
ATOM   2158  O  OH    . TYR A 1 281 ? 358.807 381.336 317.444 1.00 180.70 ? 281 TYR B OH    1 
ATOM   2159  N  N     . ARG A 1 282 ? 365.074 380.433 311.664 1.00 152.13 ? 282 ARG B N     1 
ATOM   2160  C  CA    . ARG A 1 282 ? 366.236 380.712 310.831 1.00 151.42 ? 282 ARG B CA    1 
ATOM   2161  C  C     . ARG A 1 282 ? 366.306 379.705 309.691 1.00 153.75 ? 282 ARG B C     1 
ATOM   2162  O  O     . ARG A 1 282 ? 366.390 378.495 309.929 1.00 152.42 ? 282 ARG B O     1 
ATOM   2163  C  CB    . ARG A 1 282 ? 367.515 380.664 311.665 1.00 148.02 ? 282 ARG B CB    1 
ATOM   2164  N  N     . ALA A 1 283 ? 366.274 380.206 308.457 1.00 148.19 ? 283 ALA B N     1 
ATOM   2165  C  CA    . ALA A 1 283 ? 366.483 379.372 307.281 1.00 144.81 ? 283 ALA B CA    1 
ATOM   2166  C  C     . ALA A 1 283 ? 367.980 379.231 307.042 1.00 143.63 ? 283 ALA B C     1 
ATOM   2167  O  O     . ALA A 1 283 ? 368.652 380.205 306.687 1.00 145.25 ? 283 ALA B O     1 
ATOM   2168  C  CB    . ALA A 1 283 ? 365.795 379.981 306.062 1.00 142.67 ? 283 ALA B CB    1 
ATOM   2169  N  N     . LEU A 1 284 ? 368.502 378.024 307.235 1.00 131.48 ? 284 LEU B N     1 
ATOM   2170  C  CA    . LEU A 1 284 ? 369.941 377.806 307.160 1.00 129.23 ? 284 LEU B CA    1 
ATOM   2171  C  C     . LEU A 1 284 ? 370.382 377.833 305.702 1.00 129.39 ? 284 LEU B C     1 
ATOM   2172  O  O     . LEU A 1 284 ? 369.894 377.048 304.881 1.00 129.88 ? 284 LEU B O     1 
ATOM   2173  C  CB    . LEU A 1 284 ? 370.333 376.490 307.836 1.00 129.32 ? 284 LEU B CB    1 
ATOM   2174  C  CG    . LEU A 1 284 ? 370.053 375.108 307.222 1.00 132.21 ? 284 LEU B CG    1 
ATOM   2175  C  CD1   . LEU A 1 284 ? 370.791 374.046 308.028 1.00 132.00 ? 284 LEU B CD1   1 
ATOM   2176  C  CD2   . LEU A 1 284 ? 368.566 374.781 307.143 1.00 131.10 ? 284 LEU B CD2   1 
ATOM   2177  N  N     . THR A 1 285 ? 371.279 378.763 305.380 1.00 133.55 ? 285 THR B N     1 
ATOM   2178  C  CA    . THR A 1 285 ? 371.875 378.878 304.058 1.00 130.64 ? 285 THR B CA    1 
ATOM   2179  C  C     . THR A 1 285 ? 373.357 379.187 304.222 1.00 128.92 ? 285 THR B C     1 
ATOM   2180  O  O     . THR A 1 285 ? 373.826 379.553 305.308 1.00 130.07 ? 285 THR B O     1 
ATOM   2181  C  CB    . THR A 1 285 ? 371.187 379.954 303.207 1.00 131.52 ? 285 THR B CB    1 
ATOM   2182  O  OG1   . THR A 1 285 ? 371.328 381.234 303.835 1.00 133.90 ? 285 THR B OG1   1 
ATOM   2183  C  CG2   . THR A 1 285 ? 369.709 379.632 303.012 1.00 129.38 ? 285 THR B CG2   1 
ATOM   2184  N  N     . VAL A 1 286 ? 374.098 378.992 303.127 1.00 108.59 ? 286 VAL B N     1 
ATOM   2185  C  CA    . VAL A 1 286 ? 375.537 379.274 303.140 1.00 107.78 ? 286 VAL B CA    1 
ATOM   2186  C  C     . VAL A 1 286 ? 375.826 380.726 303.495 1.00 112.58 ? 286 VAL B C     1 
ATOM   2187  O  O     . VAL A 1 286 ? 376.801 380.974 304.221 1.00 121.54 ? 286 VAL B O     1 
ATOM   2188  C  CB    . VAL A 1 286 ? 376.173 378.841 301.814 1.00 112.36 ? 286 VAL B CB    1 
ATOM   2189  C  CG1   . VAL A 1 286 ? 377.618 379.344 301.706 1.00 115.93 ? 286 VAL B CG1   1 
ATOM   2190  C  CG2   . VAL A 1 286 ? 376.126 377.325 301.669 1.00 112.29 ? 286 VAL B CG2   1 
ATOM   2191  N  N     . PRO A 1 287 ? 375.089 381.729 302.988 1.00 120.55 ? 287 PRO B N     1 
ATOM   2192  C  CA    . PRO A 1 287 ? 375.290 383.098 303.498 1.00 127.48 ? 287 PRO B CA    1 
ATOM   2193  C  C     . PRO A 1 287 ? 375.122 383.227 305.003 1.00 126.36 ? 287 PRO B C     1 
ATOM   2194  O  O     . PRO A 1 287 ? 375.937 383.894 305.658 1.00 128.95 ? 287 PRO B O     1 
ATOM   2195  C  CB    . PRO A 1 287 ? 374.225 383.903 302.745 1.00 128.17 ? 287 PRO B CB    1 
ATOM   2196  C  CG    . PRO A 1 287 ? 374.025 383.176 301.477 1.00 128.18 ? 287 PRO B CG    1 
ATOM   2197  C  CD    . PRO A 1 287 ? 374.335 381.733 301.720 1.00 121.91 ? 287 PRO B CD    1 
ATOM   2198  N  N     . GLU A 1 288 ? 374.109 382.568 305.572 1.00 119.00 ? 288 GLU B N     1 
ATOM   2199  C  CA    . GLU A 1 288 ? 373.884 382.656 307.011 1.00 120.93 ? 288 GLU B CA    1 
ATOM   2200  C  C     . GLU A 1 288 ? 375.044 382.041 307.780 1.00 124.08 ? 288 GLU B C     1 
ATOM   2201  O  O     . GLU A 1 288 ? 375.539 382.635 308.746 1.00 129.52 ? 288 GLU B O     1 
ATOM   2202  C  CB    . GLU A 1 288 ? 372.552 381.984 307.363 1.00 117.24 ? 288 GLU B CB    1 
ATOM   2203  C  CG    . GLU A 1 288 ? 372.001 382.291 308.766 1.00 125.07 ? 288 GLU B CG    1 
ATOM   2204  C  CD    . GLU A 1 288 ? 372.476 381.343 309.865 1.00 129.62 ? 288 GLU B CD    1 
ATOM   2205  O  OE1   . GLU A 1 288 ? 371.924 381.427 310.982 1.00 126.31 ? 288 GLU B OE1   1 
ATOM   2206  O  OE2   . GLU A 1 288 ? 373.355 380.492 309.625 1.00 130.59 ? 288 GLU B OE2   1 
ATOM   2207  N  N     . LEU A 1 289 ? 375.524 380.876 307.340 1.00 106.00 ? 289 LEU B N     1 
ATOM   2208  C  CA    . LEU A 1 289 ? 376.647 380.251 308.031 1.00 108.08 ? 289 LEU B CA    1 
ATOM   2209  C  C     . LEU A 1 289 ? 377.921 381.072 307.894 1.00 106.81 ? 289 LEU B C     1 
ATOM   2210  O  O     . LEU A 1 289 ? 378.686 381.191 308.857 1.00 109.09 ? 289 LEU B O     1 
ATOM   2211  C  CB    . LEU A 1 289 ? 376.885 378.835 307.516 1.00 105.68 ? 289 LEU B CB    1 
ATOM   2212  C  CG    . LEU A 1 289 ? 375.786 377.790 307.675 1.00 108.97 ? 289 LEU B CG    1 
ATOM   2213  C  CD1   . LEU A 1 289 ? 376.332 376.472 307.197 1.00 103.79 ? 289 LEU B CD1   1 
ATOM   2214  C  CD2   . LEU A 1 289 ? 375.307 377.654 309.109 1.00 113.82 ? 289 LEU B CD2   1 
ATOM   2215  N  N     . THR A 1 290 ? 378.183 381.627 306.707 1.00 103.68 ? 290 THR B N     1 
ATOM   2216  C  CA    . THR A 1 290 ? 379.401 382.409 306.525 1.00 102.14 ? 290 THR B CA    1 
ATOM   2217  C  C     . THR A 1 290 ? 379.391 383.649 307.408 1.00 107.84 ? 290 THR B C     1 
ATOM   2218  O  O     . THR A 1 290 ? 380.391 383.956 308.073 1.00 118.21 ? 290 THR B O     1 
ATOM   2219  C  CB    . THR A 1 290 ? 379.559 382.802 305.061 1.00 109.31 ? 290 THR B CB    1 
ATOM   2220  O  OG1   . THR A 1 290 ? 378.309 383.292 304.568 1.00 122.27 ? 290 THR B OG1   1 
ATOM   2221  C  CG2   . THR A 1 290 ? 379.998 381.604 304.232 1.00 107.95 ? 290 THR B CG2   1 
ATOM   2222  N  N     . GLN A 1 291 ? 378.257 384.353 307.463 1.00 109.57 ? 291 GLN B N     1 
ATOM   2223  C  CA    . GLN A 1 291 ? 378.171 385.493 308.363 1.00 114.69 ? 291 GLN B CA    1 
ATOM   2224  C  C     . GLN A 1 291 ? 378.261 385.060 309.821 1.00 114.91 ? 291 GLN B C     1 
ATOM   2225  O  O     . GLN A 1 291 ? 378.770 385.816 310.655 1.00 120.47 ? 291 GLN B O     1 
ATOM   2226  C  CB    . GLN A 1 291 ? 376.879 386.276 308.113 1.00 117.60 ? 291 GLN B CB    1 
ATOM   2227  C  CG    . GLN A 1 291 ? 376.753 386.912 306.717 1.00 120.91 ? 291 GLN B CG    1 
ATOM   2228  C  CD    . GLN A 1 291 ? 377.886 387.866 306.369 1.00 125.20 ? 291 GLN B CD    1 
ATOM   2229  O  OE1   . GLN A 1 291 ? 378.065 388.898 307.017 1.00 125.54 ? 291 GLN B OE1   1 
ATOM   2230  N  NE2   . GLN A 1 291 ? 378.657 387.523 305.341 1.00 121.32 ? 291 GLN B NE2   1 
ATOM   2231  N  N     . GLN A 1 292 ? 377.807 383.847 310.151 1.00 112.59 ? 292 GLN B N     1 
ATOM   2232  C  CA    . GLN A 1 292 ? 377.885 383.406 311.540 1.00 117.82 ? 292 GLN B CA    1 
ATOM   2233  C  C     . GLN A 1 292 ? 379.324 383.117 311.960 1.00 119.46 ? 292 GLN B C     1 
ATOM   2234  O  O     . GLN A 1 292 ? 379.753 383.539 313.040 1.00 125.90 ? 292 GLN B O     1 
ATOM   2235  C  CB    . GLN A 1 292 ? 377.006 382.180 311.766 1.00 116.59 ? 292 GLN B CB    1 
ATOM   2236  C  CG    . GLN A 1 292 ? 377.098 381.654 313.188 1.00 119.78 ? 292 GLN B CG    1 
ATOM   2237  C  CD    . GLN A 1 292 ? 375.822 380.998 313.659 1.00 121.20 ? 292 GLN B CD    1 
ATOM   2238  O  OE1   . GLN A 1 292 ? 375.768 379.787 313.854 1.00 119.59 ? 292 GLN B OE1   1 
ATOM   2239  N  NE2   . GLN A 1 292 ? 374.786 381.802 313.857 1.00 122.78 ? 292 GLN B NE2   1 
ATOM   2240  N  N     . VAL A 1 293 ? 380.086 382.389 311.134 1.00 109.84 ? 293 VAL B N     1 
ATOM   2241  C  CA    . VAL A 1 293 ? 381.482 382.130 311.502 1.00 106.18 ? 293 VAL B CA    1 
ATOM   2242  C  C     . VAL A 1 293 ? 382.296 383.417 311.489 1.00 107.37 ? 293 VAL B C     1 
ATOM   2243  O  O     . VAL A 1 293 ? 383.179 383.604 312.335 1.00 111.99 ? 293 VAL B O     1 
ATOM   2244  C  CB    . VAL A 1 293 ? 382.137 381.024 310.640 1.00 108.56 ? 293 VAL B CB    1 
ATOM   2245  C  CG1   . VAL A 1 293 ? 381.237 379.834 310.461 1.00 109.30 ? 293 VAL B CG1   1 
ATOM   2246  C  CG2   . VAL A 1 293 ? 382.509 381.537 309.260 1.00 109.91 ? 293 VAL B CG2   1 
ATOM   2247  N  N     . PHE A 1 294 ? 382.014 384.333 310.556 1.00 107.42 ? 294 PHE B N     1 
ATOM   2248  C  CA    . PHE A 1 294 ? 382.766 385.582 310.530 1.00 107.38 ? 294 PHE B CA    1 
ATOM   2249  C  C     . PHE A 1 294 ? 382.258 386.610 311.535 1.00 110.29 ? 294 PHE B C     1 
ATOM   2250  O  O     . PHE A 1 294 ? 382.889 387.661 311.685 1.00 111.83 ? 294 PHE B O     1 
ATOM   2251  C  CB    . PHE A 1 294 ? 382.760 386.159 309.116 1.00 110.44 ? 294 PHE B CB    1 
ATOM   2252  C  CG    . PHE A 1 294 ? 383.802 385.546 308.226 1.00 107.79 ? 294 PHE B CG    1 
ATOM   2253  C  CD1   . PHE A 1 294 ? 385.127 385.943 308.314 1.00 107.93 ? 294 PHE B CD1   1 
ATOM   2254  C  CD2   . PHE A 1 294 ? 383.464 384.558 307.317 1.00 108.27 ? 294 PHE B CD2   1 
ATOM   2255  C  CE1   . PHE A 1 294 ? 386.090 385.378 307.503 1.00 111.64 ? 294 PHE B CE1   1 
ATOM   2256  C  CE2   . PHE A 1 294 ? 384.424 383.989 306.502 1.00 108.34 ? 294 PHE B CE2   1 
ATOM   2257  C  CZ    . PHE A 1 294 ? 385.738 384.402 306.592 1.00 112.94 ? 294 PHE B CZ    1 
ATOM   2258  N  N     . ASP A 1 295 ? 381.148 386.342 312.221 1.00 128.37 ? 295 ASP B N     1 
ATOM   2259  C  CA    . ASP A 1 295 ? 380.759 387.160 313.362 1.00 130.33 ? 295 ASP B CA    1 
ATOM   2260  C  C     . ASP A 1 295 ? 381.721 386.921 314.519 1.00 126.62 ? 295 ASP B C     1 
ATOM   2261  O  O     . ASP A 1 295 ? 382.020 385.774 314.860 1.00 127.90 ? 295 ASP B O     1 
ATOM   2262  C  CB    . ASP A 1 295 ? 379.329 386.829 313.783 1.00 129.18 ? 295 ASP B CB    1 
ATOM   2263  C  CG    . ASP A 1 295 ? 378.806 387.757 314.863 1.00 129.93 ? 295 ASP B CG    1 
ATOM   2264  O  OD1   . ASP A 1 295 ? 379.472 388.767 315.172 1.00 130.17 ? 295 ASP B OD1   1 
ATOM   2265  O  OD2   . ASP A 1 295 ? 377.716 387.476 315.403 1.00 132.13 ? 295 ASP B OD2   1 
ATOM   2266  N  N     . ALA A 1 296 ? 382.184 388.010 315.141 1.00 115.16 ? 296 ALA B N     1 
ATOM   2267  C  CA    . ALA A 1 296 ? 383.212 387.908 316.174 1.00 113.71 ? 296 ALA B CA    1 
ATOM   2268  C  C     . ALA A 1 296 ? 382.721 387.156 317.404 1.00 113.75 ? 296 ALA B C     1 
ATOM   2269  O  O     . ALA A 1 296 ? 383.473 386.366 317.985 1.00 114.66 ? 296 ALA B O     1 
ATOM   2270  C  CB    . ALA A 1 296 ? 383.689 389.304 316.575 1.00 113.83 ? 296 ALA B CB    1 
ATOM   2271  N  N     . LYS A 1 297 ? 381.468 387.374 317.805 1.00 108.47 ? 297 LYS B N     1 
ATOM   2272  C  CA    . LYS A 1 297 ? 380.934 386.716 318.993 1.00 107.63 ? 297 LYS B CA    1 
ATOM   2273  C  C     . LYS A 1 297 ? 380.869 385.199 318.848 1.00 106.57 ? 297 LYS B C     1 
ATOM   2274  O  O     . LYS A 1 297 ? 380.806 384.497 319.862 1.00 105.72 ? 297 LYS B O     1 
ATOM   2275  C  CB    . LYS A 1 297 ? 379.540 387.260 319.306 1.00 100.67 ? 297 LYS B CB    1 
ATOM   2276  N  N     . ASN A 1 298 ? 380.878 384.680 317.620 1.00 111.01 ? 298 ASN B N     1 
ATOM   2277  C  CA    . ASN A 1 298 ? 380.920 383.243 317.399 1.00 112.47 ? 298 ASN B CA    1 
ATOM   2278  C  C     . ASN A 1 298 ? 382.302 382.644 317.656 1.00 117.78 ? 298 ASN B C     1 
ATOM   2279  O  O     . ASN A 1 298 ? 382.389 381.432 317.888 1.00 116.24 ? 298 ASN B O     1 
ATOM   2280  C  CB    . ASN A 1 298 ? 380.455 382.948 315.964 1.00 118.98 ? 298 ASN B CB    1 
ATOM   2281  C  CG    . ASN A 1 298 ? 380.518 381.468 315.600 1.00 120.95 ? 298 ASN B CG    1 
ATOM   2282  O  OD1   . ASN A 1 298 ? 381.591 380.916 315.351 1.00 119.67 ? 298 ASN B OD1   1 
ATOM   2283  N  ND2   . ASN A 1 298 ? 379.360 380.822 315.568 1.00 120.39 ? 298 ASN B ND2   1 
ATOM   2284  N  N     . MET A 1 299 ? 383.371 383.450 317.642 1.00 118.90 ? 299 MET B N     1 
ATOM   2285  C  CA    . MET A 1 299 ? 384.722 382.901 317.758 1.00 112.49 ? 299 MET B CA    1 
ATOM   2286  C  C     . MET A 1 299 ? 384.929 382.211 319.098 1.00 116.17 ? 299 MET B C     1 
ATOM   2287  O  O     . MET A 1 299 ? 384.478 382.690 320.142 1.00 119.28 ? 299 MET B O     1 
ATOM   2288  C  CB    . MET A 1 299 ? 385.795 383.983 317.597 1.00 113.72 ? 299 MET B CB    1 
ATOM   2289  C  CG    . MET A 1 299 ? 386.775 383.743 316.444 1.00 118.25 ? 299 MET B CG    1 
ATOM   2290  S  SD    . MET A 1 299 ? 386.079 383.564 314.787 1.00 126.99 ? 299 MET B SD    1 
ATOM   2291  C  CE    . MET A 1 299 ? 384.969 384.961 314.729 1.00 120.76 ? 299 MET B CE    1 
ATOM   2292  N  N     . MET A 1 300 ? 385.631 381.082 319.059 1.00 115.54 ? 300 MET B N     1 
ATOM   2293  C  CA    . MET A 1 300 ? 385.803 380.247 320.236 1.00 114.12 ? 300 MET B CA    1 
ATOM   2294  C  C     . MET A 1 300 ? 386.960 380.707 321.121 1.00 114.47 ? 300 MET B C     1 
ATOM   2295  O  O     . MET A 1 300 ? 387.211 380.072 322.150 1.00 118.16 ? 300 MET B O     1 
ATOM   2296  C  CB    . MET A 1 300 ? 386.016 378.788 319.810 1.00 119.36 ? 300 MET B CB    1 
ATOM   2297  C  CG    . MET A 1 300 ? 384.726 377.982 319.708 1.00 121.18 ? 300 MET B CG    1 
ATOM   2298  S  SD    . MET A 1 300 ? 384.792 376.704 318.450 1.00 131.53 ? 300 MET B SD    1 
ATOM   2299  C  CE    . MET A 1 300 ? 385.976 375.605 319.222 1.00 123.15 ? 300 MET B CE    1 
ATOM   2300  N  N     . ALA A 1 301 ? 387.680 381.765 320.736 1.00 117.83 ? 301 ALA B N     1 
ATOM   2301  C  CA    . ALA A 1 301 ? 388.665 382.432 321.575 1.00 118.18 ? 301 ALA B CA    1 
ATOM   2302  C  C     . ALA A 1 301 ? 388.158 383.825 321.919 1.00 123.77 ? 301 ALA B C     1 
ATOM   2303  O  O     . ALA A 1 301 ? 387.444 384.449 321.128 1.00 126.48 ? 301 ALA B O     1 
ATOM   2304  C  CB    . ALA A 1 301 ? 390.021 382.522 320.875 1.00 116.86 ? 301 ALA B CB    1 
ATOM   2305  N  N     . ALA A 1 302 ? 388.524 384.308 323.107 1.00 129.77 ? 302 ALA B N     1 
ATOM   2306  C  CA    . ALA A 1 302 ? 387.969 385.560 323.608 1.00 130.56 ? 302 ALA B CA    1 
ATOM   2307  C  C     . ALA A 1 302 ? 388.429 386.782 322.820 1.00 128.16 ? 302 ALA B C     1 
ATOM   2308  O  O     . ALA A 1 302 ? 387.785 387.832 322.911 1.00 127.00 ? 302 ALA B O     1 
ATOM   2309  C  CB    . ALA A 1 302 ? 388.334 385.737 325.081 1.00 128.71 ? 302 ALA B CB    1 
ATOM   2310  N  N     . CYS A 1 303 ? 389.518 386.683 322.060 1.00 125.41 ? 303 CYS B N     1 
ATOM   2311  C  CA    . CYS A 1 303 ? 390.046 387.851 321.366 1.00 126.74 ? 303 CYS B CA    1 
ATOM   2312  C  C     . CYS A 1 303 ? 389.123 388.283 320.235 1.00 124.86 ? 303 CYS B C     1 
ATOM   2313  O  O     . CYS A 1 303 ? 388.647 387.455 319.453 1.00 124.50 ? 303 CYS B O     1 
ATOM   2314  C  CB    . CYS A 1 303 ? 391.440 387.556 320.823 1.00 128.11 ? 303 CYS B CB    1 
ATOM   2315  S  SG    . CYS A 1 303 ? 392.659 387.320 322.116 1.00 145.55 ? 303 CYS B SG    1 
ATOM   2316  N  N     . ASP A 1 304 ? 388.876 389.585 320.152 1.00 128.43 ? 304 ASP B N     1 
ATOM   2317  C  CA    . ASP A 1 304 ? 388.047 390.137 319.091 1.00 131.57 ? 304 ASP B CA    1 
ATOM   2318  C  C     . ASP A 1 304 ? 388.883 390.287 317.821 1.00 128.88 ? 304 ASP B C     1 
ATOM   2319  O  O     . ASP A 1 304 ? 389.865 391.041 317.836 1.00 131.86 ? 304 ASP B O     1 
ATOM   2320  C  CB    . ASP A 1 304 ? 387.494 391.492 319.508 1.00 130.52 ? 304 ASP B CB    1 
ATOM   2321  C  CG    . ASP A 1 304 ? 386.313 391.928 318.665 1.00 134.43 ? 304 ASP B CG    1 
ATOM   2322  O  OD1   . ASP A 1 304 ? 386.065 391.310 317.610 1.00 135.16 ? 304 ASP B OD1   1 
ATOM   2323  O  OD2   . ASP A 1 304 ? 385.632 392.896 319.060 1.00 136.27 ? 304 ASP B OD2   1 
ATOM   2324  N  N     . PRO A 1 305 ? 388.539 389.621 316.703 1.00 105.03 ? 305 PRO B N     1 
ATOM   2325  C  CA    . PRO A 1 305 ? 389.354 389.801 315.485 1.00 110.12 ? 305 PRO B CA    1 
ATOM   2326  C  C     . PRO A 1 305 ? 389.361 391.223 314.961 1.00 117.87 ? 305 PRO B C     1 
ATOM   2327  O  O     . PRO A 1 305 ? 390.328 391.616 314.293 1.00 122.61 ? 305 PRO B O     1 
ATOM   2328  C  CB    . PRO A 1 305 ? 388.712 388.843 314.471 1.00 107.89 ? 305 PRO B CB    1 
ATOM   2329  C  CG    . PRO A 1 305 ? 387.859 387.940 315.248 1.00 107.20 ? 305 PRO B CG    1 
ATOM   2330  C  CD    . PRO A 1 305 ? 387.426 388.684 316.452 1.00 106.92 ? 305 PRO B CD    1 
ATOM   2331  N  N     . ARG A 1 306 ? 388.331 392.016 315.269 1.00 121.45 ? 306 ARG B N     1 
ATOM   2332  C  CA    . ARG A 1 306 ? 388.327 393.414 314.857 1.00 121.00 ? 306 ARG B CA    1 
ATOM   2333  C  C     . ARG A 1 306 ? 389.462 394.194 315.508 1.00 120.81 ? 306 ARG B C     1 
ATOM   2334  O  O     . ARG A 1 306 ? 389.924 395.189 314.941 1.00 123.78 ? 306 ARG B O     1 
ATOM   2335  C  CB    . ARG A 1 306 ? 386.985 394.085 315.181 1.00 119.51 ? 306 ARG B CB    1 
ATOM   2336  C  CG    . ARG A 1 306 ? 385.713 393.337 314.759 1.00 118.66 ? 306 ARG B CG    1 
ATOM   2337  C  CD    . ARG A 1 306 ? 384.489 393.988 315.381 1.00 121.86 ? 306 ARG B CD    1 
ATOM   2338  N  NE    . ARG A 1 306 ? 384.192 393.433 316.702 1.00 126.80 ? 306 ARG B NE    1 
ATOM   2339  C  CZ    . ARG A 1 306 ? 383.166 392.649 317.027 1.00 128.26 ? 306 ARG B CZ    1 
ATOM   2340  N  NH1   . ARG A 1 306 ? 382.266 392.248 316.137 1.00 129.02 ? 306 ARG B NH1   1 
ATOM   2341  N  NH2   . ARG A 1 306 ? 383.039 392.249 318.287 1.00 125.18 ? 306 ARG B NH2   1 
ATOM   2342  N  N     . HIS A 1 307 ? 389.929 393.766 316.686 1.00 112.52 ? 307 HIS B N     1 
ATOM   2343  C  CA    . HIS A 1 307 ? 391.086 394.425 317.276 1.00 112.46 ? 307 HIS B CA    1 
ATOM   2344  C  C     . HIS A 1 307 ? 392.362 394.172 316.484 1.00 112.29 ? 307 HIS B C     1 
ATOM   2345  O  O     . HIS A 1 307 ? 393.284 394.991 316.559 1.00 118.83 ? 307 HIS B O     1 
ATOM   2346  C  CB    . HIS A 1 307 ? 391.291 393.971 318.725 1.00 114.05 ? 307 HIS B CB    1 
ATOM   2347  C  CG    . HIS A 1 307 ? 390.326 394.573 319.702 1.00 117.79 ? 307 HIS B CG    1 
ATOM   2348  N  ND1   . HIS A 1 307 ? 389.842 395.859 319.590 1.00 119.35 ? 307 HIS B ND1   1 
ATOM   2349  C  CD2   . HIS A 1 307 ? 389.776 394.065 320.831 1.00 115.94 ? 307 HIS B CD2   1 
ATOM   2350  C  CE1   . HIS A 1 307 ? 389.021 396.110 320.593 1.00 119.54 ? 307 HIS B CE1   1 
ATOM   2351  N  NE2   . HIS A 1 307 ? 388.964 395.038 321.362 1.00 118.73 ? 307 HIS B NE2   1 
ATOM   2352  N  N     . GLY A 1 308 ? 392.432 393.069 315.731 1.00 97.05  ? 308 GLY B N     1 
ATOM   2353  C  CA    . GLY A 1 308 ? 393.604 392.724 314.943 1.00 100.36 ? 308 GLY B CA    1 
ATOM   2354  C  C     . GLY A 1 308 ? 393.311 392.667 313.459 1.00 100.35 ? 308 GLY B C     1 
ATOM   2355  O  O     . GLY A 1 308 ? 392.385 393.324 312.975 1.00 97.75  ? 308 GLY B O     1 
ATOM   2356  N  N     . ARG A 1 309 ? 394.110 391.888 312.732 1.00 113.77 ? 309 ARG B N     1 
ATOM   2357  C  CA    . ARG A 1 309 ? 393.908 391.642 311.313 1.00 109.94 ? 309 ARG B CA    1 
ATOM   2358  C  C     . ARG A 1 309 ? 394.110 390.162 311.042 1.00 107.98 ? 309 ARG B C     1 
ATOM   2359  O  O     . ARG A 1 309 ? 394.870 389.484 311.738 1.00 114.71 ? 309 ARG B O     1 
ATOM   2360  C  CB    . ARG A 1 309 ? 394.867 392.465 310.443 1.00 112.45 ? 309 ARG B CB    1 
ATOM   2361  C  CG    . ARG A 1 309 ? 394.353 393.852 310.101 1.00 112.75 ? 309 ARG B CG    1 
ATOM   2362  C  CD    . ARG A 1 309 ? 395.306 394.596 309.179 1.00 108.84 ? 309 ARG B CD    1 
ATOM   2363  N  NE    . ARG A 1 309 ? 394.616 395.634 308.420 1.00 114.27 ? 309 ARG B NE    1 
ATOM   2364  C  CZ    . ARG A 1 309 ? 395.204 396.630 307.766 1.00 119.19 ? 309 ARG B CZ    1 
ATOM   2365  N  NH1   . ARG A 1 309 ? 396.522 396.769 307.735 1.00 124.56 ? 309 ARG B NH1   1 
ATOM   2366  N  NH2   . ARG A 1 309 ? 394.447 397.512 307.119 1.00 116.79 ? 309 ARG B NH2   1 
ATOM   2367  N  N     . TYR A 1 310 ? 393.422 389.669 310.020 1.00 97.84  ? 310 TYR B N     1 
ATOM   2368  C  CA    . TYR A 1 310 ? 393.494 388.267 309.642 1.00 96.31  ? 310 TYR B CA    1 
ATOM   2369  C  C     . TYR A 1 310 ? 394.697 388.045 308.737 1.00 96.67  ? 310 TYR B C     1 
ATOM   2370  O  O     . TYR A 1 310 ? 394.798 388.657 307.669 1.00 98.90  ? 310 TYR B O     1 
ATOM   2371  C  CB    . TYR A 1 310 ? 392.215 387.839 308.924 1.00 100.59 ? 310 TYR B CB    1 
ATOM   2372  C  CG    . TYR A 1 310 ? 391.071 387.489 309.844 1.00 97.62  ? 310 TYR B CG    1 
ATOM   2373  C  CD1   . TYR A 1 310 ? 391.050 386.286 310.530 1.00 97.70  ? 310 TYR B CD1   1 
ATOM   2374  C  CD2   . TYR A 1 310 ? 390.009 388.363 310.022 1.00 99.38  ? 310 TYR B CD2   1 
ATOM   2375  C  CE1   . TYR A 1 310 ? 390.005 385.964 311.371 1.00 101.19 ? 310 TYR B CE1   1 
ATOM   2376  C  CE2   . TYR A 1 310 ? 388.960 388.050 310.860 1.00 95.54  ? 310 TYR B CE2   1 
ATOM   2377  C  CZ    . TYR A 1 310 ? 388.963 386.850 311.532 1.00 99.31  ? 310 TYR B CZ    1 
ATOM   2378  O  OH    . TYR A 1 310 ? 387.918 386.535 312.368 1.00 98.06  ? 310 TYR B OH    1 
ATOM   2379  N  N     . LEU A 1 311 ? 395.606 387.170 309.165 1.00 99.52  ? 311 LEU B N     1 
ATOM   2380  C  CA    . LEU A 1 311 ? 396.695 386.733 308.300 1.00 98.38  ? 311 LEU B CA    1 
ATOM   2381  C  C     . LEU A 1 311 ? 396.178 385.734 307.273 1.00 95.50  ? 311 LEU B C     1 
ATOM   2382  O  O     . LEU A 1 311 ? 396.352 385.927 306.066 1.00 104.18 ? 311 LEU B O     1 
ATOM   2383  C  CB    . LEU A 1 311 ? 397.829 386.111 309.123 1.00 100.43 ? 311 LEU B CB    1 
ATOM   2384  C  CG    . LEU A 1 311 ? 398.461 386.956 310.227 1.00 98.92  ? 311 LEU B CG    1 
ATOM   2385  C  CD1   . LEU A 1 311 ? 399.264 386.075 311.164 1.00 95.65  ? 311 LEU B CD1   1 
ATOM   2386  C  CD2   . LEU A 1 311 ? 399.344 388.031 309.627 1.00 98.21  ? 311 LEU B CD2   1 
ATOM   2387  N  N     . THR A 1 312 ? 395.546 384.661 307.746 1.00 89.76  ? 312 THR B N     1 
ATOM   2388  C  CA    . THR A 1 312 ? 394.932 383.668 306.877 1.00 84.58  ? 312 THR B CA    1 
ATOM   2389  C  C     . THR A 1 312 ? 393.657 383.152 307.526 1.00 95.34  ? 312 THR B C     1 
ATOM   2390  O  O     . THR A 1 312 ? 393.478 383.236 308.743 1.00 105.38 ? 312 THR B O     1 
ATOM   2391  C  CB    . THR A 1 312 ? 395.882 382.497 306.574 1.00 87.03  ? 312 THR B CB    1 
ATOM   2392  O  OG1   . THR A 1 312 ? 396.303 381.887 307.798 1.00 95.33  ? 312 THR B OG1   1 
ATOM   2393  C  CG2   . THR A 1 312 ? 397.102 382.960 305.791 1.00 102.09 ? 312 THR B CG2   1 
ATOM   2394  N  N     . VAL A 1 313 ? 392.764 382.635 306.688 1.00 100.32 ? 313 VAL B N     1 
ATOM   2395  C  CA    . VAL A 1 313 ? 391.462 382.130 307.105 1.00 95.88  ? 313 VAL B CA    1 
ATOM   2396  C  C     . VAL A 1 313 ? 391.211 380.839 306.344 1.00 94.70  ? 313 VAL B C     1 
ATOM   2397  O  O     . VAL A 1 313 ? 391.622 380.708 305.189 1.00 102.76 ? 313 VAL B O     1 
ATOM   2398  C  CB    . VAL A 1 313 ? 390.346 383.164 306.840 1.00 93.90  ? 313 VAL B CB    1 
ATOM   2399  C  CG1   . VAL A 1 313 ? 388.977 382.557 307.088 1.00 92.77  ? 313 VAL B CG1   1 
ATOM   2400  C  CG2   . VAL A 1 313 ? 390.556 384.404 307.707 1.00 97.73  ? 313 VAL B CG2   1 
ATOM   2401  N  N     . ALA A 1 314 ? 390.590 379.864 307.008 1.00 88.46  ? 314 ALA B N     1 
ATOM   2402  C  CA    . ALA A 1 314 ? 390.234 378.593 306.396 1.00 86.77  ? 314 ALA B CA    1 
ATOM   2403  C  C     . ALA A 1 314 ? 388.834 378.196 306.828 1.00 89.35  ? 314 ALA B C     1 
ATOM   2404  O  O     . ALA A 1 314 ? 388.435 378.420 307.975 1.00 99.05  ? 314 ALA B O     1 
ATOM   2405  C  CB    . ALA A 1 314 ? 391.222 377.483 306.767 1.00 79.71  ? 314 ALA B CB    1 
ATOM   2406  N  N     . ALA A 1 315 ? 388.098 377.587 305.893 1.00 91.13  ? 315 ALA B N     1 
ATOM   2407  C  CA    . ALA A 1 315 ? 386.704 377.207 306.127 1.00 87.49  ? 315 ALA B CA    1 
ATOM   2408  C  C     . ALA A 1 315 ? 386.485 375.821 305.531 1.00 91.69  ? 315 ALA B C     1 
ATOM   2409  O  O     . ALA A 1 315 ? 386.506 375.660 304.306 1.00 99.99  ? 315 ALA B O     1 
ATOM   2410  C  CB    . ALA A 1 315 ? 385.749 378.224 305.522 1.00 86.04  ? 315 ALA B CB    1 
ATOM   2411  N  N     . VAL A 1 316 ? 386.282 374.838 306.405 1.00 87.37  ? 316 VAL B N     1 
ATOM   2412  C  CA    . VAL A 1 316 ? 385.957 373.473 306.005 1.00 85.70  ? 316 VAL B CA    1 
ATOM   2413  C  C     . VAL A 1 316 ? 384.447 373.311 306.144 1.00 91.78  ? 316 VAL B C     1 
ATOM   2414  O  O     . VAL A 1 316 ? 383.918 373.264 307.256 1.00 95.74  ? 316 VAL B O     1 
ATOM   2415  C  CB    . VAL A 1 316 ? 386.714 372.445 306.855 1.00 88.65  ? 316 VAL B CB    1 
ATOM   2416  C  CG1   . VAL A 1 316 ? 386.612 371.052 306.241 1.00 92.53  ? 316 VAL B CG1   1 
ATOM   2417  C  CG2   . VAL A 1 316 ? 388.174 372.863 307.014 1.00 82.88  ? 316 VAL B CG2   1 
ATOM   2418  N  N     . PHE A 1 317 ? 383.753 373.239 305.014 1.00 91.15  ? 317 PHE B N     1 
ATOM   2419  C  CA    . PHE A 1 317 ? 382.311 373.069 304.976 1.00 91.75  ? 317 PHE B CA    1 
ATOM   2420  C  C     . PHE A 1 317 ? 381.980 371.587 304.940 1.00 93.10  ? 317 PHE B C     1 
ATOM   2421  O  O     . PHE A 1 317 ? 382.765 370.780 304.437 1.00 92.52  ? 317 PHE B O     1 
ATOM   2422  C  CB    . PHE A 1 317 ? 381.725 373.748 303.740 1.00 86.63  ? 317 PHE B CB    1 
ATOM   2423  C  CG    . PHE A 1 317 ? 381.742 375.247 303.796 1.00 87.59  ? 317 PHE B CG    1 
ATOM   2424  C  CD1   . PHE A 1 317 ? 382.912 375.950 303.574 1.00 91.80  ? 317 PHE B CD1   1 
ATOM   2425  C  CD2   . PHE A 1 317 ? 380.582 375.953 304.047 1.00 89.77  ? 317 PHE B CD2   1 
ATOM   2426  C  CE1   . PHE A 1 317 ? 382.928 377.325 303.618 1.00 92.35  ? 317 PHE B CE1   1 
ATOM   2427  C  CE2   . PHE A 1 317 ? 380.592 377.330 304.090 1.00 93.75  ? 317 PHE B CE2   1 
ATOM   2428  C  CZ    . PHE A 1 317 ? 381.766 378.017 303.874 1.00 92.62  ? 317 PHE B CZ    1 
ATOM   2429  N  N     . ARG A 1 318 ? 380.803 371.239 305.452 1.00 103.43 ? 318 ARG B N     1 
ATOM   2430  C  CA    . ARG A 1 318 ? 380.323 369.866 305.486 1.00 98.79  ? 318 ARG B CA    1 
ATOM   2431  C  C     . ARG A 1 318 ? 378.851 369.862 305.113 1.00 101.03 ? 318 ARG B C     1 
ATOM   2432  O  O     . ARG A 1 318 ? 378.082 370.696 305.602 1.00 106.67 ? 318 ARG B O     1 
ATOM   2433  C  CB    . ARG A 1 318 ? 380.534 369.252 306.870 1.00 101.15 ? 318 ARG B CB    1 
ATOM   2434  C  CG    . ARG A 1 318 ? 381.987 368.941 307.187 1.00 103.74 ? 318 ARG B CG    1 
ATOM   2435  C  CD    . ARG A 1 318 ? 382.134 368.261 308.533 1.00 104.25 ? 318 ARG B CD    1 
ATOM   2436  N  NE    . ARG A 1 318 ? 381.556 366.922 308.536 1.00 107.58 ? 318 ARG B NE    1 
ATOM   2437  C  CZ    . ARG A 1 318 ? 381.562 366.087 309.568 1.00 108.33 ? 318 ARG B CZ    1 
ATOM   2438  N  NH1   . ARG A 1 318 ? 382.122 366.407 310.725 1.00 108.43 ? 318 ARG B NH1   1 
ATOM   2439  N  NH2   . ARG A 1 318 ? 380.983 364.897 309.440 1.00 106.07 ? 318 ARG B NH2   1 
ATOM   2440  N  N     . GLY A 1 319 ? 378.471 368.924 304.246 1.00 113.00 ? 319 GLY B N     1 
ATOM   2441  C  CA    . GLY A 1 319 ? 377.116 368.807 303.740 1.00 117.25 ? 319 GLY B CA    1 
ATOM   2442  C  C     . GLY A 1 319 ? 377.095 368.911 302.230 1.00 121.14 ? 319 GLY B C     1 
ATOM   2443  O  O     . GLY A 1 319 ? 378.065 368.526 301.571 1.00 118.56 ? 319 GLY B O     1 
ATOM   2444  N  N     . ARG A 1 320 ? 376.001 369.439 301.679 1.00 116.98 ? 320 ARG B N     1 
ATOM   2445  C  CA    . ARG A 1 320 ? 375.853 369.665 300.244 1.00 108.53 ? 320 ARG B CA    1 
ATOM   2446  C  C     . ARG A 1 320 ? 375.539 371.134 300.017 1.00 112.11 ? 320 ARG B C     1 
ATOM   2447  O  O     . ARG A 1 320 ? 374.550 371.648 300.549 1.00 110.60 ? 320 ARG B O     1 
ATOM   2448  C  CB    . ARG A 1 320 ? 374.748 368.785 299.656 1.00 101.32 ? 320 ARG B CB    1 
ATOM   2449  N  N     . MET A 1 321 ? 376.382 371.805 299.237 1.00 113.92 ? 321 MET B N     1 
ATOM   2450  C  CA    . MET A 1 321 ? 376.151 373.198 298.884 1.00 114.62 ? 321 MET B CA    1 
ATOM   2451  C  C     . MET A 1 321 ? 376.860 373.464 297.568 1.00 111.59 ? 321 MET B C     1 
ATOM   2452  O  O     . MET A 1 321 ? 377.959 372.953 297.338 1.00 110.42 ? 321 MET B O     1 
ATOM   2453  C  CB    . MET A 1 321 ? 376.677 374.185 299.939 1.00 116.01 ? 321 MET B CB    1 
ATOM   2454  C  CG    . MET A 1 321 ? 378.106 373.953 300.447 1.00 111.90 ? 321 MET B CG    1 
ATOM   2455  S  SD    . MET A 1 321 ? 378.240 373.819 302.238 1.00 106.68 ? 321 MET B SD    1 
ATOM   2456  C  CE    . MET A 1 321 ? 377.390 372.274 302.509 1.00 114.56 ? 321 MET B CE    1 
ATOM   2457  N  N     . SER A 1 322 ? 376.229 374.257 296.709 1.00 112.32 ? 322 SER B N     1 
ATOM   2458  C  CA    . SER A 1 322 ? 376.925 374.760 295.536 1.00 114.86 ? 322 SER B CA    1 
ATOM   2459  C  C     . SER A 1 322 ? 378.086 375.639 295.980 1.00 111.33 ? 322 SER B C     1 
ATOM   2460  O  O     . SER A 1 322 ? 377.938 376.462 296.884 1.00 120.47 ? 322 SER B O     1 
ATOM   2461  C  CB    . SER A 1 322 ? 375.963 375.564 294.664 1.00 119.96 ? 322 SER B CB    1 
ATOM   2462  O  OG    . SER A 1 322 ? 375.577 376.753 295.327 1.00 117.18 ? 322 SER B OG    1 
ATOM   2463  N  N     . MET A 1 323 ? 379.250 375.451 295.360 1.00 92.13  ? 323 MET B N     1 
ATOM   2464  C  CA    . MET A 1 323 ? 380.437 376.203 295.761 1.00 100.57 ? 323 MET B CA    1 
ATOM   2465  C  C     . MET A 1 323 ? 380.549 377.575 295.107 1.00 101.98 ? 323 MET B C     1 
ATOM   2466  O  O     . MET A 1 323 ? 381.415 378.359 295.523 1.00 110.80 ? 323 MET B O     1 
ATOM   2467  C  CB    . MET A 1 323 ? 381.693 375.377 295.484 1.00 98.26  ? 323 MET B CB    1 
ATOM   2468  C  CG    . MET A 1 323 ? 381.852 374.222 296.468 1.00 110.92 ? 323 MET B CG    1 
ATOM   2469  S  SD    . MET A 1 323 ? 383.530 373.595 296.622 1.00 132.35 ? 323 MET B SD    1 
ATOM   2470  C  CE    . MET A 1 323 ? 383.982 373.402 294.924 1.00 112.44 ? 323 MET B CE    1 
ATOM   2471  N  N     . LYS A 1 324 ? 379.680 377.910 294.148 1.00 93.99  ? 324 LYS B N     1 
ATOM   2472  C  CA    . LYS A 1 324 ? 379.605 379.276 293.646 1.00 102.42 ? 324 LYS B CA    1 
ATOM   2473  C  C     . LYS A 1 324 ? 379.278 380.213 294.796 1.00 107.97 ? 324 LYS B C     1 
ATOM   2474  O  O     . LYS A 1 324 ? 379.934 381.242 294.963 1.00 114.89 ? 324 LYS B O     1 
ATOM   2475  C  CB    . LYS A 1 324 ? 378.543 379.420 292.544 1.00 100.32 ? 324 LYS B CB    1 
ATOM   2476  C  CG    . LYS A 1 324 ? 378.089 380.876 292.249 1.00 100.99 ? 324 LYS B CG    1 
ATOM   2477  C  CD    . LYS A 1 324 ? 377.250 380.993 290.975 1.00 105.11 ? 324 LYS B CD    1 
ATOM   2478  C  CE    . LYS A 1 324 ? 376.754 382.426 290.691 1.00 108.35 ? 324 LYS B CE    1 
ATOM   2479  N  NZ    . LYS A 1 324 ? 377.040 383.447 291.745 1.00 109.57 ? 324 LYS B NZ    1 
ATOM   2480  N  N     . GLU A 1 325 ? 378.249 379.876 295.579 1.00 113.28 ? 325 GLU B N     1 
ATOM   2481  C  CA    . GLU A 1 325 ? 377.838 380.770 296.652 1.00 117.57 ? 325 GLU B CA    1 
ATOM   2482  C  C     . GLU A 1 325 ? 378.793 380.733 297.828 1.00 119.37 ? 325 GLU B C     1 
ATOM   2483  O  O     . GLU A 1 325 ? 378.919 381.744 298.525 1.00 125.31 ? 325 GLU B O     1 
ATOM   2484  C  CB    . GLU A 1 325 ? 376.398 380.468 297.080 1.00 114.34 ? 325 GLU B CB    1 
ATOM   2485  C  CG    . GLU A 1 325 ? 376.184 379.188 297.863 1.00 115.44 ? 325 GLU B CG    1 
ATOM   2486  C  CD    . GLU A 1 325 ? 374.713 378.861 298.070 1.00 120.58 ? 325 GLU B CD    1 
ATOM   2487  O  OE1   . GLU A 1 325 ? 373.884 379.204 297.201 1.00 118.30 ? 325 GLU B OE1   1 
ATOM   2488  O  OE2   . GLU A 1 325 ? 374.383 378.252 299.109 1.00 123.55 ? 325 GLU B OE2   1 
ATOM   2489  N  N     . VAL A 1 326 ? 379.501 379.622 298.037 1.00 108.53 ? 326 VAL B N     1 
ATOM   2490  C  CA    . VAL A 1 326 ? 380.597 379.616 299.002 1.00 111.00 ? 326 VAL B CA    1 
ATOM   2491  C  C     . VAL A 1 326 ? 381.638 380.654 298.603 1.00 114.34 ? 326 VAL B C     1 
ATOM   2492  O  O     . VAL A 1 326 ? 382.038 381.508 299.409 1.00 123.69 ? 326 VAL B O     1 
ATOM   2493  C  CB    . VAL A 1 326 ? 381.212 378.208 299.106 1.00 105.27 ? 326 VAL B CB    1 
ATOM   2494  C  CG1   . VAL A 1 326 ? 382.501 378.231 299.923 1.00 105.82 ? 326 VAL B CG1   1 
ATOM   2495  C  CG2   . VAL A 1 326 ? 380.219 377.231 299.725 1.00 110.24 ? 326 VAL B CG2   1 
ATOM   2496  N  N     . ASP A 1 327 ? 382.051 380.627 297.332 1.00 117.84 ? 327 ASP B N     1 
ATOM   2497  C  CA    . ASP A 1 327 ? 383.042 381.585 296.856 1.00 119.05 ? 327 ASP B CA    1 
ATOM   2498  C  C     . ASP A 1 327 ? 382.523 383.021 296.908 1.00 122.95 ? 327 ASP B C     1 
ATOM   2499  O  O     . ASP A 1 327 ? 383.248 383.923 297.349 1.00 129.73 ? 327 ASP B O     1 
ATOM   2500  C  CB    . ASP A 1 327 ? 383.474 381.219 295.438 1.00 118.16 ? 327 ASP B CB    1 
ATOM   2501  C  CG    . ASP A 1 327 ? 384.124 379.851 295.359 1.00 121.65 ? 327 ASP B CG    1 
ATOM   2502  O  OD1   . ASP A 1 327 ? 384.642 379.370 296.389 1.00 122.57 ? 327 ASP B OD1   1 
ATOM   2503  O  OD2   . ASP A 1 327 ? 384.121 379.256 294.263 1.00 125.29 ? 327 ASP B OD2   1 
ATOM   2504  N  N     . GLU A 1 328 ? 381.276 383.265 296.476 1.00 124.42 ? 328 GLU B N     1 
ATOM   2505  C  CA    . GLU A 1 328 ? 380.817 384.650 296.440 1.00 124.47 ? 328 GLU B CA    1 
ATOM   2506  C  C     . GLU A 1 328 ? 380.603 385.183 297.848 1.00 124.18 ? 328 GLU B C     1 
ATOM   2507  O  O     . GLU A 1 328 ? 380.878 386.352 298.113 1.00 129.20 ? 328 GLU B O     1 
ATOM   2508  C  CB    . GLU A 1 328 ? 379.548 384.862 295.592 1.00 123.09 ? 328 GLU B CB    1 
ATOM   2509  C  CG    . GLU A 1 328 ? 378.170 384.872 296.297 1.00 126.37 ? 328 GLU B CG    1 
ATOM   2510  C  CD    . GLU A 1 328 ? 377.018 384.516 295.360 1.00 129.41 ? 328 GLU B CD    1 
ATOM   2511  O  OE1   . GLU A 1 328 ? 376.433 383.420 295.447 1.00 131.02 ? 328 GLU B OE1   1 
ATOM   2512  O  OE2   . GLU A 1 328 ? 376.682 385.374 294.518 1.00 130.69 ? 328 GLU B OE2   1 
ATOM   2513  N  N     . GLN A 1 329 ? 380.128 384.347 298.772 1.00 113.46 ? 329 GLN B N     1 
ATOM   2514  C  CA    . GLN A 1 329 ? 379.978 384.817 300.141 1.00 117.14 ? 329 GLN B CA    1 
ATOM   2515  C  C     . GLN A 1 329 ? 381.335 385.090 300.767 1.00 120.17 ? 329 GLN B C     1 
ATOM   2516  O  O     . GLN A 1 329 ? 381.486 386.053 301.528 1.00 125.32 ? 329 GLN B O     1 
ATOM   2517  C  CB    . GLN A 1 329 ? 379.187 383.803 300.965 1.00 114.28 ? 329 GLN B CB    1 
ATOM   2518  C  CG    . GLN A 1 329 ? 377.700 383.782 300.645 1.00 114.07 ? 329 GLN B CG    1 
ATOM   2519  C  CD    . GLN A 1 329 ? 376.988 385.048 301.096 1.00 120.46 ? 329 GLN B CD    1 
ATOM   2520  O  OE1   . GLN A 1 329 ? 377.176 385.510 302.221 1.00 121.88 ? 329 GLN B OE1   1 
ATOM   2521  N  NE2   . GLN A 1 329 ? 376.180 385.623 300.213 1.00 123.38 ? 329 GLN B NE2   1 
ATOM   2522  N  N     . MET A 1 330 ? 382.345 384.288 300.423 1.00 112.97 ? 330 MET B N     1 
ATOM   2523  C  CA    . MET A 1 330 ? 383.687 384.570 300.915 1.00 113.24 ? 330 MET B CA    1 
ATOM   2524  C  C     . MET A 1 330 ? 384.204 385.893 300.358 1.00 116.04 ? 330 MET B C     1 
ATOM   2525  O  O     . MET A 1 330 ? 384.882 386.650 301.062 1.00 125.09 ? 330 MET B O     1 
ATOM   2526  C  CB    . MET A 1 330 ? 384.626 383.416 300.543 1.00 108.83 ? 330 MET B CB    1 
ATOM   2527  C  CG    . MET A 1 330 ? 384.610 382.204 301.498 1.00 112.35 ? 330 MET B CG    1 
ATOM   2528  S  SD    . MET A 1 330 ? 384.762 382.497 303.278 1.00 139.04 ? 330 MET B SD    1 
ATOM   2529  C  CE    . MET A 1 330 ? 384.585 380.834 303.900 1.00 121.89 ? 330 MET B CE    1 
ATOM   2530  N  N     . LEU A 1 331 ? 383.865 386.208 299.106 1.00 118.86 ? 331 LEU B N     1 
ATOM   2531  C  CA    . LEU A 1 331 ? 384.309 387.478 298.531 1.00 120.65 ? 331 LEU B CA    1 
ATOM   2532  C  C     . LEU A 1 331 ? 383.555 388.676 299.096 1.00 127.81 ? 331 LEU B C     1 
ATOM   2533  O  O     . LEU A 1 331 ? 384.162 389.730 299.302 1.00 131.78 ? 331 LEU B O     1 
ATOM   2534  C  CB    . LEU A 1 331 ? 384.186 387.452 297.010 1.00 117.89 ? 331 LEU B CB    1 
ATOM   2535  C  CG    . LEU A 1 331 ? 385.454 387.120 296.204 1.00 123.76 ? 331 LEU B CG    1 
ATOM   2536  C  CD1   . LEU A 1 331 ? 386.327 385.960 296.743 1.00 126.07 ? 331 LEU B CD1   1 
ATOM   2537  C  CD2   . LEU A 1 331 ? 385.074 386.858 294.750 1.00 125.21 ? 331 LEU B CD2   1 
ATOM   2538  N  N     . ASN A 1 332 ? 382.245 388.558 299.327 1.00 127.60 ? 332 ASN B N     1 
ATOM   2539  C  CA    . ASN A 1 332 ? 381.537 389.610 300.061 1.00 123.49 ? 332 ASN B CA    1 
ATOM   2540  C  C     . ASN A 1 332 ? 382.119 389.806 301.453 1.00 123.69 ? 332 ASN B C     1 
ATOM   2541  O  O     . ASN A 1 332 ? 382.221 390.943 301.931 1.00 127.76 ? 332 ASN B O     1 
ATOM   2542  C  CB    . ASN A 1 332 ? 380.033 389.327 300.137 1.00 123.24 ? 332 ASN B CB    1 
ATOM   2543  C  CG    . ASN A 1 332 ? 379.414 389.022 298.786 1.00 124.86 ? 332 ASN B CG    1 
ATOM   2544  O  OD1   . ASN A 1 332 ? 380.110 388.819 297.796 1.00 124.69 ? 332 ASN B OD1   1 
ATOM   2545  N  ND2   . ASN A 1 332 ? 378.088 388.966 298.749 1.00 125.55 ? 332 ASN B ND2   1 
ATOM   2546  N  N     . VAL A 1 333 ? 382.527 388.717 302.110 1.00 119.70 ? 333 VAL B N     1 
ATOM   2547  C  CA    . VAL A 1 333 ? 383.196 388.843 303.401 1.00 122.03 ? 333 VAL B CA    1 
ATOM   2548  C  C     . VAL A 1 333 ? 384.496 389.624 303.251 1.00 124.63 ? 333 VAL B C     1 
ATOM   2549  O  O     . VAL A 1 333 ? 384.788 390.526 304.044 1.00 132.97 ? 333 VAL B O     1 
ATOM   2550  C  CB    . VAL A 1 333 ? 383.438 387.452 304.017 1.00 121.07 ? 333 VAL B CB    1 
ATOM   2551  C  CG1   . VAL A 1 333 ? 384.476 387.513 305.131 1.00 121.95 ? 333 VAL B CG1   1 
ATOM   2552  C  CG2   . VAL A 1 333 ? 382.138 386.883 304.559 1.00 122.38 ? 333 VAL B CG2   1 
ATOM   2553  N  N     . GLN A 1 334 ? 385.297 389.283 302.241 1.00 122.35 ? 334 GLN B N     1 
ATOM   2554  C  CA    . GLN A 1 334 ? 386.583 389.952 302.061 1.00 121.69 ? 334 GLN B CA    1 
ATOM   2555  C  C     . GLN A 1 334 ? 386.397 391.427 301.723 1.00 120.90 ? 334 GLN B C     1 
ATOM   2556  O  O     . GLN A 1 334 ? 387.166 392.278 302.183 1.00 127.24 ? 334 GLN B O     1 
ATOM   2557  C  CB    . GLN A 1 334 ? 387.393 389.249 300.971 1.00 123.81 ? 334 GLN B CB    1 
ATOM   2558  C  CG    . GLN A 1 334 ? 388.068 387.951 301.419 1.00 120.49 ? 334 GLN B CG    1 
ATOM   2559  C  CD    . GLN A 1 334 ? 389.350 387.659 300.662 1.00 119.03 ? 334 GLN B CD    1 
ATOM   2560  O  OE1   . GLN A 1 334 ? 390.372 387.328 301.262 1.00 112.91 ? 334 GLN B OE1   1 
ATOM   2561  N  NE2   . GLN A 1 334 ? 389.300 387.768 299.338 1.00 119.60 ? 334 GLN B NE2   1 
ATOM   2562  N  N     . ASN A 1 335 ? 385.382 391.749 300.919 1.00 114.07 ? 335 ASN B N     1 
ATOM   2563  C  CA    . ASN A 1 335 ? 385.139 393.142 300.564 1.00 117.42 ? 335 ASN B CA    1 
ATOM   2564  C  C     . ASN A 1 335 ? 384.645 393.943 301.763 1.00 119.52 ? 335 ASN B C     1 
ATOM   2565  O  O     . ASN A 1 335 ? 385.084 395.079 301.973 1.00 121.66 ? 335 ASN B O     1 
ATOM   2566  C  CB    . ASN A 1 335 ? 384.134 393.235 299.413 1.00 119.55 ? 335 ASN B CB    1 
ATOM   2567  C  CG    . ASN A 1 335 ? 384.597 392.508 298.156 1.00 119.32 ? 335 ASN B CG    1 
ATOM   2568  O  OD1   . ASN A 1 335 ? 383.836 391.749 297.557 1.00 120.80 ? 335 ASN B OD1   1 
ATOM   2569  N  ND2   . ASN A 1 335 ? 385.837 392.750 297.740 1.00 119.45 ? 335 ASN B ND2   1 
ATOM   2570  N  N     . LYS A 1 336 ? 383.735 393.378 302.562 1.00 120.80 ? 336 LYS B N     1 
ATOM   2571  C  CA    . LYS A 1 336 ? 383.243 394.116 303.722 1.00 120.28 ? 336 LYS B CA    1 
ATOM   2572  C  C     . LYS A 1 336 ? 384.314 394.253 304.802 1.00 121.56 ? 336 LYS B C     1 
ATOM   2573  O  O     . LYS A 1 336 ? 384.359 395.270 305.505 1.00 117.72 ? 336 LYS B O     1 
ATOM   2574  C  CB    . LYS A 1 336 ? 381.955 393.466 304.258 1.00 118.92 ? 336 LYS B CB    1 
ATOM   2575  C  CG    . LYS A 1 336 ? 382.063 392.153 305.077 1.00 123.75 ? 336 LYS B CG    1 
ATOM   2576  C  CD    . LYS A 1 336 ? 381.118 392.117 306.278 1.00 125.72 ? 336 LYS B CD    1 
ATOM   2577  C  CE    . LYS A 1 336 ? 379.667 391.925 305.869 1.00 128.52 ? 336 LYS B CE    1 
ATOM   2578  N  NZ    . LYS A 1 336 ? 379.396 390.517 305.490 1.00 126.81 ? 336 LYS B NZ    1 
ATOM   2579  N  N     . ASN A 1 337 ? 385.188 393.251 304.939 1.00 137.40 ? 337 ASN B N     1 
ATOM   2580  C  CA    . ASN A 1 337 ? 386.222 393.205 305.968 1.00 135.77 ? 337 ASN B CA    1 
ATOM   2581  C  C     . ASN A 1 337 ? 387.616 393.433 305.390 1.00 137.88 ? 337 ASN B C     1 
ATOM   2582  O  O     . ASN A 1 337 ? 388.600 392.895 305.912 1.00 138.36 ? 337 ASN B O     1 
ATOM   2583  C  CB    . ASN A 1 337 ? 386.154 391.866 306.705 1.00 136.38 ? 337 ASN B CB    1 
ATOM   2584  C  CG    . ASN A 1 337 ? 384.884 391.713 307.515 1.00 135.19 ? 337 ASN B CG    1 
ATOM   2585  O  OD1   . ASN A 1 337 ? 384.057 392.623 307.574 1.00 131.31 ? 337 ASN B OD1   1 
ATOM   2586  N  ND2   . ASN A 1 337 ? 384.721 390.556 308.146 1.00 138.60 ? 337 ASN B ND2   1 
ATOM   2587  N  N     . SER A 1 338 ? 387.719 394.232 304.323 1.00 124.13 ? 338 SER B N     1 
ATOM   2588  C  CA    . SER A 1 338 ? 389.014 394.482 303.695 1.00 121.32 ? 338 SER B CA    1 
ATOM   2589  C  C     . SER A 1 338 ? 389.981 395.174 304.647 1.00 121.38 ? 338 SER B C     1 
ATOM   2590  O  O     . SER A 1 338 ? 391.199 394.993 304.534 1.00 120.27 ? 338 SER B O     1 
ATOM   2591  C  CB    . SER A 1 338 ? 388.827 395.320 302.430 1.00 120.42 ? 338 SER B CB    1 
ATOM   2592  O  OG    . SER A 1 338 ? 388.159 396.535 302.718 1.00 118.84 ? 338 SER B OG    1 
ATOM   2593  N  N     . SER A 1 339 ? 389.463 395.964 305.589 1.00 119.81 ? 339 SER B N     1 
ATOM   2594  C  CA    . SER A 1 339 ? 390.318 396.542 306.618 1.00 117.44 ? 339 SER B CA    1 
ATOM   2595  C  C     . SER A 1 339 ? 390.908 395.472 307.527 1.00 111.24 ? 339 SER B C     1 
ATOM   2596  O  O     . SER A 1 339 ? 392.022 395.642 308.034 1.00 114.94 ? 339 SER B O     1 
ATOM   2597  C  CB    . SER A 1 339 ? 389.526 397.553 307.446 1.00 114.15 ? 339 SER B CB    1 
ATOM   2598  O  OG    . SER A 1 339 ? 388.837 398.468 306.611 1.00 117.81 ? 339 SER B OG    1 
ATOM   2599  N  N     . TYR A 1 340 ? 390.188 394.370 307.740 1.00 104.44 ? 340 TYR B N     1 
ATOM   2600  C  CA    . TYR A 1 340 ? 390.584 393.341 308.693 1.00 107.85 ? 340 TYR B CA    1 
ATOM   2601  C  C     . TYR A 1 340 ? 391.448 392.235 308.092 1.00 110.40 ? 340 TYR B C     1 
ATOM   2602  O  O     . TYR A 1 340 ? 391.775 391.286 308.812 1.00 112.88 ? 340 TYR B O     1 
ATOM   2603  C  CB    . TYR A 1 340 ? 389.336 392.717 309.327 1.00 104.52 ? 340 TYR B CB    1 
ATOM   2604  C  CG    . TYR A 1 340 ? 388.412 393.723 309.977 1.00 110.37 ? 340 TYR B CG    1 
ATOM   2605  C  CD1   . TYR A 1 340 ? 388.841 394.503 311.042 1.00 112.22 ? 340 TYR B CD1   1 
ATOM   2606  C  CD2   . TYR A 1 340 ? 387.112 393.895 309.524 1.00 110.46 ? 340 TYR B CD2   1 
ATOM   2607  C  CE1   . TYR A 1 340 ? 388.001 395.424 311.637 1.00 113.34 ? 340 TYR B CE1   1 
ATOM   2608  C  CE2   . TYR A 1 340 ? 386.265 394.813 310.112 1.00 111.12 ? 340 TYR B CE2   1 
ATOM   2609  C  CZ    . TYR A 1 340 ? 386.714 395.574 311.168 1.00 112.73 ? 340 TYR B CZ    1 
ATOM   2610  O  OH    . TYR A 1 340 ? 385.873 396.489 311.756 1.00 110.08 ? 340 TYR B OH    1 
ATOM   2611  N  N     . PHE A 1 341 ? 391.816 392.322 306.811 1.00 114.08 ? 341 PHE B N     1 
ATOM   2612  C  CA    . PHE A 1 341 ? 392.718 391.375 306.162 1.00 110.82 ? 341 PHE B CA    1 
ATOM   2613  C  C     . PHE A 1 341 ? 394.016 392.079 305.794 1.00 111.05 ? 341 PHE B C     1 
ATOM   2614  O  O     . PHE A 1 341 ? 394.000 393.193 305.263 1.00 120.34 ? 341 PHE B O     1 
ATOM   2615  C  CB    . PHE A 1 341 ? 392.081 390.772 304.907 1.00 111.47 ? 341 PHE B CB    1 
ATOM   2616  C  CG    . PHE A 1 341 ? 391.002 389.769 305.197 1.00 110.77 ? 341 PHE B CG    1 
ATOM   2617  C  CD1   . PHE A 1 341 ? 391.322 388.475 305.563 1.00 110.50 ? 341 PHE B CD1   1 
ATOM   2618  C  CD2   . PHE A 1 341 ? 389.669 390.117 305.098 1.00 109.21 ? 341 PHE B CD2   1 
ATOM   2619  C  CE1   . PHE A 1 341 ? 390.335 387.551 305.831 1.00 110.74 ? 341 PHE B CE1   1 
ATOM   2620  C  CE2   . PHE A 1 341 ? 388.676 389.197 305.363 1.00 107.52 ? 341 PHE B CE2   1 
ATOM   2621  C  CZ    . PHE A 1 341 ? 389.010 387.913 305.730 1.00 111.38 ? 341 PHE B CZ    1 
ATOM   2622  N  N     . VAL A 1 342 ? 395.140 391.421 306.082 1.00 94.91  ? 342 VAL B N     1 
ATOM   2623  C  CA    . VAL A 1 342 ? 396.446 392.012 305.817 1.00 98.45  ? 342 VAL B CA    1 
ATOM   2624  C  C     . VAL A 1 342 ? 396.653 392.156 304.315 1.00 103.47 ? 342 VAL B C     1 
ATOM   2625  O  O     . VAL A 1 342 ? 396.332 391.253 303.532 1.00 98.89  ? 342 VAL B O     1 
ATOM   2626  C  CB    . VAL A 1 342 ? 397.568 391.175 306.458 1.00 98.57  ? 342 VAL B CB    1 
ATOM   2627  C  CG1   . VAL A 1 342 ? 397.392 391.123 307.967 1.00 102.80 ? 342 VAL B CG1   1 
ATOM   2628  C  CG2   . VAL A 1 342 ? 397.654 389.761 305.860 1.00 103.13 ? 342 VAL B CG2   1 
ATOM   2629  N  N     . GLU A 1 343 ? 397.193 393.308 303.909 1.00 118.82 ? 343 GLU B N     1 
ATOM   2630  C  CA    . GLU A 1 343 ? 397.357 393.600 302.487 1.00 113.46 ? 343 GLU B CA    1 
ATOM   2631  C  C     . GLU A 1 343 ? 398.375 392.672 301.837 1.00 109.16 ? 343 GLU B C     1 
ATOM   2632  O  O     . GLU A 1 343 ? 398.175 392.222 300.703 1.00 110.08 ? 343 GLU B O     1 
ATOM   2633  C  CB    . GLU A 1 343 ? 397.780 395.058 302.292 1.00 118.58 ? 343 GLU B CB    1 
ATOM   2634  C  CG    . GLU A 1 343 ? 396.825 396.105 302.871 1.00 119.05 ? 343 GLU B CG    1 
ATOM   2635  C  CD    . GLU A 1 343 ? 395.543 396.248 302.073 1.00 116.85 ? 343 GLU B CD    1 
ATOM   2636  O  OE1   . GLU A 1 343 ? 395.363 395.511 301.081 1.00 115.36 ? 343 GLU B OE1   1 
ATOM   2637  O  OE2   . GLU A 1 343 ? 394.709 397.101 302.443 1.00 115.73 ? 343 GLU B OE2   1 
ATOM   2638  N  N     . TRP A 1 344 ? 399.473 392.377 302.536 1.00 89.59  ? 344 TRP B N     1 
ATOM   2639  C  CA    . TRP A 1 344 ? 400.556 391.600 301.937 1.00 88.22  ? 344 TRP B CA    1 
ATOM   2640  C  C     . TRP A 1 344 ? 400.158 390.159 301.626 1.00 93.12  ? 344 TRP B C     1 
ATOM   2641  O  O     . TRP A 1 344 ? 400.859 389.500 300.851 1.00 99.03  ? 344 TRP B O     1 
ATOM   2642  C  CB    . TRP A 1 344 ? 401.801 391.628 302.834 1.00 82.27  ? 344 TRP B CB    1 
ATOM   2643  C  CG    . TRP A 1 344 ? 401.623 391.096 304.229 1.00 83.33  ? 344 TRP B CG    1 
ATOM   2644  C  CD1   . TRP A 1 344 ? 401.182 391.786 305.321 1.00 88.45  ? 344 TRP B CD1   1 
ATOM   2645  C  CD2   . TRP A 1 344 ? 401.905 389.769 304.683 1.00 89.27  ? 344 TRP B CD2   1 
ATOM   2646  N  NE1   . TRP A 1 344 ? 401.161 390.968 306.421 1.00 92.37  ? 344 TRP B NE1   1 
ATOM   2647  C  CE2   . TRP A 1 344 ? 401.602 389.724 306.057 1.00 93.27  ? 344 TRP B CE2   1 
ATOM   2648  C  CE3   . TRP A 1 344 ? 402.379 388.612 304.060 1.00 94.59  ? 344 TRP B CE3   1 
ATOM   2649  C  CZ2   . TRP A 1 344 ? 401.756 388.570 306.817 1.00 94.20  ? 344 TRP B CZ2   1 
ATOM   2650  C  CZ3   . TRP A 1 344 ? 402.533 387.469 304.817 1.00 97.52  ? 344 TRP B CZ3   1 
ATOM   2651  C  CH2   . TRP A 1 344 ? 402.219 387.455 306.180 1.00 94.58  ? 344 TRP B CH2   1 
ATOM   2652  N  N     . ILE A 1 345 ? 399.069 389.659 302.207 1.00 95.57  ? 345 ILE B N     1 
ATOM   2653  C  CA    . ILE A 1 345 ? 398.418 388.436 301.739 1.00 92.44  ? 345 ILE B CA    1 
ATOM   2654  C  C     . ILE A 1 345 ? 397.347 388.860 300.731 1.00 96.30  ? 345 ILE B C     1 
ATOM   2655  O  O     . ILE A 1 345 ? 396.385 389.538 301.126 1.00 99.81  ? 345 ILE B O     1 
ATOM   2656  C  CB    . ILE A 1 345 ? 397.795 387.643 302.898 1.00 88.88  ? 345 ILE B CB    1 
ATOM   2657  C  CG1   . ILE A 1 345 ? 398.874 387.140 303.877 1.00 94.02  ? 345 ILE B CG1   1 
ATOM   2658  C  CG2   . ILE A 1 345 ? 396.937 386.475 302.369 1.00 90.81  ? 345 ILE B CG2   1 
ATOM   2659  C  CD1   . ILE A 1 345 ? 399.561 385.842 303.462 1.00 96.16  ? 345 ILE B CD1   1 
ATOM   2660  N  N     . PRO A 1 346 ? 397.466 388.498 299.427 1.00 84.51  ? 346 PRO B N     1 
ATOM   2661  C  CA    . PRO A 1 346 ? 396.453 388.975 298.473 1.00 85.08  ? 346 PRO B CA    1 
ATOM   2662  C  C     . PRO A 1 346 ? 395.091 388.341 298.697 1.00 92.68  ? 346 PRO B C     1 
ATOM   2663  O  O     . PRO A 1 346 ? 394.070 389.036 298.678 1.00 100.31 ? 346 PRO B O     1 
ATOM   2664  C  CB    . PRO A 1 346 ? 397.038 388.585 297.112 1.00 92.26  ? 346 PRO B CB    1 
ATOM   2665  C  CG    . PRO A 1 346 ? 397.899 387.437 297.390 1.00 96.42  ? 346 PRO B CG    1 
ATOM   2666  C  CD    . PRO A 1 346 ? 398.477 387.669 298.744 1.00 86.61  ? 346 PRO B CD    1 
ATOM   2667  N  N     . ASN A 1 347 ? 395.072 387.024 298.901 1.00 101.26 ? 347 ASN B N     1 
ATOM   2668  C  CA    . ASN A 1 347 ? 393.862 386.277 299.219 1.00 105.97 ? 347 ASN B CA    1 
ATOM   2669  C  C     . ASN A 1 347 ? 394.139 385.413 300.436 1.00 108.83 ? 347 ASN B C     1 
ATOM   2670  O  O     . ASN A 1 347 ? 395.108 384.648 300.449 1.00 111.18 ? 347 ASN B O     1 
ATOM   2671  C  CB    . ASN A 1 347 ? 393.414 385.414 298.040 1.00 105.54 ? 347 ASN B CB    1 
ATOM   2672  C  CG    . ASN A 1 347 ? 391.998 384.906 298.203 1.00 113.22 ? 347 ASN B CG    1 
ATOM   2673  O  OD1   . ASN A 1 347 ? 391.714 384.110 299.097 1.00 117.12 ? 347 ASN B OD1   1 
ATOM   2674  N  ND2   . ASN A 1 347 ? 391.096 385.369 297.343 1.00 112.65 ? 347 ASN B ND2   1 
ATOM   2675  N  N     . ASN A 1 348 ? 393.281 385.532 301.449 1.00 115.58 ? 348 ASN B N     1 
ATOM   2676  C  CA    . ASN A 1 348 ? 393.499 384.916 302.751 1.00 115.43 ? 348 ASN B CA    1 
ATOM   2677  C  C     . ASN A 1 348 ? 392.709 383.632 302.968 1.00 115.42 ? 348 ASN B C     1 
ATOM   2678  O  O     . ASN A 1 348 ? 393.009 382.901 303.918 1.00 122.24 ? 348 ASN B O     1 
ATOM   2679  C  CB    . ASN A 1 348 ? 393.131 385.909 303.859 1.00 119.69 ? 348 ASN B CB    1 
ATOM   2680  C  CG    . ASN A 1 348 ? 393.797 387.256 303.679 1.00 122.17 ? 348 ASN B CG    1 
ATOM   2681  O  OD1   . ASN A 1 348 ? 393.405 388.043 302.818 1.00 117.29 ? 348 ASN B OD1   1 
ATOM   2682  N  ND2   . ASN A 1 348 ? 394.806 387.532 304.496 1.00 125.99 ? 348 ASN B ND2   1 
ATOM   2683  N  N     . VAL A 1 349 ? 391.723 383.331 302.125 1.00 103.66 ? 349 VAL B N     1 
ATOM   2684  C  CA    . VAL A 1 349 ? 390.738 382.291 302.399 1.00 102.85 ? 349 VAL B CA    1 
ATOM   2685  C  C     . VAL A 1 349 ? 391.181 380.986 301.753 1.00 104.85 ? 349 VAL B C     1 
ATOM   2686  O  O     . VAL A 1 349 ? 391.604 380.967 300.591 1.00 107.50 ? 349 VAL B O     1 
ATOM   2687  C  CB    . VAL A 1 349 ? 389.343 382.703 301.900 1.00 100.61 ? 349 VAL B CB    1 
ATOM   2688  C  CG1   . VAL A 1 349 ? 388.306 381.658 302.311 1.00 103.49 ? 349 VAL B CG1   1 
ATOM   2689  C  CG2   . VAL A 1 349 ? 388.973 384.094 302.434 1.00 95.73  ? 349 VAL B CG2   1 
ATOM   2690  N  N     . LYS A 1 350 ? 391.086 379.899 302.518 1.00 96.59  ? 350 LYS B N     1 
ATOM   2691  C  CA    . LYS A 1 350 ? 391.324 378.532 302.059 1.00 90.35  ? 350 LYS B CA    1 
ATOM   2692  C  C     . LYS A 1 350 ? 390.012 377.774 302.241 1.00 95.12  ? 350 LYS B C     1 
ATOM   2693  O  O     . LYS A 1 350 ? 389.631 377.423 303.364 1.00 104.03 ? 350 LYS B O     1 
ATOM   2694  C  CB    . LYS A 1 350 ? 392.476 377.887 302.833 1.00 88.31  ? 350 LYS B CB    1 
ATOM   2695  C  CG    . LYS A 1 350 ? 392.601 376.363 302.712 1.00 89.33  ? 350 LYS B CG    1 
ATOM   2696  C  CD    . LYS A 1 350 ? 392.598 375.876 301.269 1.00 94.12  ? 350 LYS B CD    1 
ATOM   2697  C  CE    . LYS A 1 350 ? 392.916 374.395 301.191 1.00 96.98  ? 350 LYS B CE    1 
ATOM   2698  N  NZ    . LYS A 1 350 ? 392.417 373.784 299.930 1.00 97.55  ? 350 LYS B NZ    1 
ATOM   2699  N  N     . THR A 1 351 ? 389.324 377.528 301.134 1.00 107.74 ? 351 THR B N     1 
ATOM   2700  C  CA    . THR A 1 351 ? 388.046 376.836 301.146 1.00 108.19 ? 351 THR B CA    1 
ATOM   2701  C  C     . THR A 1 351 ? 388.257 375.331 301.054 1.00 103.31 ? 351 THR B C     1 
ATOM   2702  O  O     . THR A 1 351 ? 389.188 374.851 300.403 1.00 104.93 ? 351 THR B O     1 
ATOM   2703  C  CB    . THR A 1 351 ? 387.176 377.313 299.981 1.00 109.53 ? 351 THR B CB    1 
ATOM   2704  O  OG1   . THR A 1 351 ? 387.153 378.745 299.959 1.00 113.52 ? 351 THR B OG1   1 
ATOM   2705  C  CG2   . THR A 1 351 ? 385.749 376.795 300.108 1.00 108.79 ? 351 THR B CG2   1 
ATOM   2706  N  N     . ALA A 1 352 ? 387.379 374.589 301.724 1.00 97.29  ? 352 ALA B N     1 
ATOM   2707  C  CA    . ALA A 1 352 ? 387.308 373.145 301.569 1.00 94.54  ? 352 ALA B CA    1 
ATOM   2708  C  C     . ALA A 1 352 ? 385.864 372.733 301.792 1.00 97.30  ? 352 ALA B C     1 
ATOM   2709  O  O     . ALA A 1 352 ? 385.140 373.387 302.542 1.00 103.83 ? 352 ALA B O     1 
ATOM   2710  C  CB    . ALA A 1 352 ? 388.234 372.418 302.549 1.00 99.23  ? 352 ALA B CB    1 
ATOM   2711  N  N     . VAL A 1 353 ? 385.446 371.659 301.124 1.00 94.62  ? 353 VAL B N     1 
ATOM   2712  C  CA    . VAL A 1 353 ? 384.073 371.164 301.196 1.00 94.26  ? 353 VAL B CA    1 
ATOM   2713  C  C     . VAL A 1 353 ? 384.094 369.646 301.296 1.00 103.22 ? 353 VAL B C     1 
ATOM   2714  O  O     . VAL A 1 353 ? 384.902 368.977 300.643 1.00 108.82 ? 353 VAL B O     1 
ATOM   2715  C  CB    . VAL A 1 353 ? 383.235 371.631 299.985 1.00 87.02  ? 353 VAL B CB    1 
ATOM   2716  C  CG1   . VAL A 1 353 ? 381.807 371.065 300.054 1.00 91.09  ? 353 VAL B CG1   1 
ATOM   2717  C  CG2   . VAL A 1 353 ? 383.214 373.162 299.931 1.00 90.88  ? 353 VAL B CG2   1 
ATOM   2718  N  N     . CYS A 1 354 ? 383.197 369.112 302.127 1.00 110.20 ? 354 CYS B N     1 
ATOM   2719  C  CA    . CYS A 1 354 ? 383.005 367.683 302.314 1.00 107.20 ? 354 CYS B CA    1 
ATOM   2720  C  C     . CYS A 1 354 ? 381.526 367.362 302.160 1.00 110.98 ? 354 CYS B C     1 
ATOM   2721  O  O     . CYS A 1 354 ? 380.659 368.162 302.519 1.00 113.46 ? 354 CYS B O     1 
ATOM   2722  C  CB    . CYS A 1 354 ? 383.507 367.229 303.688 1.00 105.41 ? 354 CYS B CB    1 
ATOM   2723  S  SG    . CYS A 1 354 ? 383.044 365.545 304.136 1.00 122.80 ? 354 CYS B SG    1 
ATOM   2724  N  N     . ASP A 1 355 ? 381.246 366.176 301.620 1.00 111.84 ? 355 ASP B N     1 
ATOM   2725  C  CA    . ASP A 1 355 ? 379.882 365.845 301.219 1.00 110.58 ? 355 ASP B CA    1 
ATOM   2726  C  C     . ASP A 1 355 ? 378.992 365.538 302.418 1.00 106.92 ? 355 ASP B C     1 
ATOM   2727  O  O     . ASP A 1 355 ? 377.827 365.950 302.450 1.00 111.44 ? 355 ASP B O     1 
ATOM   2728  C  CB    . ASP A 1 355 ? 379.904 364.658 300.256 1.00 115.58 ? 355 ASP B CB    1 
ATOM   2729  C  CG    . ASP A 1 355 ? 380.237 365.065 298.833 1.00 116.69 ? 355 ASP B CG    1 
ATOM   2730  O  OD1   . ASP A 1 355 ? 379.593 365.996 298.306 1.00 116.39 ? 355 ASP B OD1   1 
ATOM   2731  O  OD2   . ASP A 1 355 ? 381.154 364.456 298.243 1.00 113.76 ? 355 ASP B OD2   1 
ATOM   2732  N  N     . ILE A 1 356 ? 379.513 364.822 303.408 1.00 97.54  ? 356 ILE B N     1 
ATOM   2733  C  CA    . ILE A 1 356 ? 378.698 364.228 304.464 1.00 103.17 ? 356 ILE B CA    1 
ATOM   2734  C  C     . ILE A 1 356 ? 378.614 365.223 305.624 1.00 98.79  ? 356 ILE B C     1 
ATOM   2735  O  O     . ILE A 1 356 ? 379.665 365.610 306.157 1.00 97.14  ? 356 ILE B O     1 
ATOM   2736  C  CB    . ILE A 1 356 ? 379.252 362.878 304.944 1.00 108.60 ? 356 ILE B CB    1 
ATOM   2737  C  CG1   . ILE A 1 356 ? 380.005 362.098 303.845 1.00 103.64 ? 356 ILE B CG1   1 
ATOM   2738  C  CG2   . ILE A 1 356 ? 378.133 362.026 305.540 1.00 107.37 ? 356 ILE B CG2   1 
ATOM   2739  C  CD1   . ILE A 1 356 ? 379.199 361.798 302.565 1.00 106.78 ? 356 ILE B CD1   1 
ATOM   2740  N  N     . PRO A 1 357 ? 377.417 365.650 306.052 1.00 99.82  ? 357 PRO B N     1 
ATOM   2741  C  CA    . PRO A 1 357 ? 377.336 366.591 307.182 1.00 104.50 ? 357 PRO B CA    1 
ATOM   2742  C  C     . PRO A 1 357 ? 377.316 365.861 308.515 1.00 106.49 ? 357 PRO B C     1 
ATOM   2743  O  O     . PRO A 1 357 ? 377.152 364.632 308.549 1.00 111.93 ? 357 PRO B O     1 
ATOM   2744  C  CB    . PRO A 1 357 ? 376.014 367.321 306.929 1.00 106.92 ? 357 PRO B CB    1 
ATOM   2745  C  CG    . PRO A 1 357 ? 375.173 366.304 306.288 1.00 102.40 ? 357 PRO B CG    1 
ATOM   2746  C  CD    . PRO A 1 357 ? 376.072 365.423 305.482 1.00 99.01  ? 357 PRO B CD    1 
ATOM   2747  N  N     . PRO A 1 358 ? 377.471 366.591 309.653 1.00 113.14 ? 358 PRO B N     1 
ATOM   2748  C  CA    . PRO A 1 358 ? 377.555 365.925 310.963 1.00 116.63 ? 358 PRO B CA    1 
ATOM   2749  C  C     . PRO A 1 358 ? 376.234 365.873 311.732 1.00 123.37 ? 358 PRO B C     1 
ATOM   2750  O  O     . PRO A 1 358 ? 375.456 366.832 311.693 1.00 125.33 ? 358 PRO B O     1 
ATOM   2751  C  CB    . PRO A 1 358 ? 378.591 366.787 311.690 1.00 116.55 ? 358 PRO B CB    1 
ATOM   2752  C  CG    . PRO A 1 358 ? 378.319 368.172 311.180 1.00 118.02 ? 358 PRO B CG    1 
ATOM   2753  C  CD    . PRO A 1 358 ? 377.745 368.036 309.782 1.00 116.11 ? 358 PRO B CD    1 
ATOM   2754  N  N     . ARG A 1 359 ? 375.986 364.763 312.444 1.00 131.61 ? 359 ARG B N     1 
ATOM   2755  C  CA    . ARG A 1 359 ? 374.810 364.572 313.315 1.00 131.62 ? 359 ARG B CA    1 
ATOM   2756  C  C     . ARG A 1 359 ? 373.489 364.786 312.573 1.00 131.92 ? 359 ARG B C     1 
ATOM   2757  O  O     . ARG A 1 359 ? 372.497 365.235 313.152 1.00 134.44 ? 359 ARG B O     1 
ATOM   2758  C  CB    . ARG A 1 359 ? 374.867 365.477 314.556 1.00 135.55 ? 359 ARG B CB    1 
ATOM   2759  C  CG    . ARG A 1 359 ? 376.008 365.184 315.525 1.00 135.12 ? 359 ARG B CG    1 
ATOM   2760  C  CD    . ARG A 1 359 ? 376.035 366.180 316.650 1.00 138.54 ? 359 ARG B CD    1 
ATOM   2761  N  NE    . ARG A 1 359 ? 374.852 366.133 317.504 1.00 142.08 ? 359 ARG B NE    1 
ATOM   2762  C  CZ    . ARG A 1 359 ? 374.594 366.986 318.489 1.00 140.00 ? 359 ARG B CZ    1 
ATOM   2763  N  NH1   . ARG A 1 359 ? 375.420 367.979 318.789 1.00 135.20 ? 359 ARG B NH1   1 
ATOM   2764  N  NH2   . ARG A 1 359 ? 373.467 366.849 319.180 1.00 139.33 ? 359 ARG B NH2   1 
ATOM   2765  N  N     . GLY A 1 360 ? 373.449 364.471 311.284 1.00 123.68 ? 360 GLY B N     1 
ATOM   2766  C  CA    . GLY A 1 360 ? 372.221 364.612 310.533 1.00 129.87 ? 360 GLY B CA    1 
ATOM   2767  C  C     . GLY A 1 360 ? 371.792 366.033 310.241 1.00 133.59 ? 360 GLY B C     1 
ATOM   2768  O  O     . GLY A 1 360 ? 370.685 366.228 309.725 1.00 134.52 ? 360 GLY B O     1 
ATOM   2769  N  N     . LEU A 1 361 ? 372.611 367.034 310.557 1.00 129.05 ? 361 LEU B N     1 
ATOM   2770  C  CA    . LEU A 1 361 ? 372.328 368.385 310.099 1.00 126.88 ? 361 LEU B CA    1 
ATOM   2771  C  C     . LEU A 1 361 ? 372.424 368.433 308.583 1.00 126.81 ? 361 LEU B C     1 
ATOM   2772  O  O     . LEU A 1 361 ? 373.136 367.644 307.963 1.00 130.79 ? 361 LEU B O     1 
ATOM   2773  C  CB    . LEU A 1 361 ? 373.305 369.398 310.706 1.00 125.97 ? 361 LEU B CB    1 
ATOM   2774  C  CG    . LEU A 1 361 ? 372.772 370.270 311.845 1.00 128.29 ? 361 LEU B CG    1 
ATOM   2775  C  CD1   . LEU A 1 361 ? 373.921 370.887 312.628 1.00 128.93 ? 361 LEU B CD1   1 
ATOM   2776  C  CD2   . LEU A 1 361 ? 371.854 371.359 311.301 1.00 123.42 ? 361 LEU B CD2   1 
ATOM   2777  N  N     . LYS A 1 362 ? 371.678 369.355 307.980 1.00 106.63 ? 362 LYS B N     1 
ATOM   2778  C  CA    . LYS A 1 362 ? 371.783 369.529 306.536 1.00 105.68 ? 362 LYS B CA    1 
ATOM   2779  C  C     . LYS A 1 362 ? 373.098 370.190 306.141 1.00 114.07 ? 362 LYS B C     1 
ATOM   2780  O  O     . LYS A 1 362 ? 373.521 370.063 304.987 1.00 113.56 ? 362 LYS B O     1 
ATOM   2781  C  CB    . LYS A 1 362 ? 370.601 370.349 306.005 1.00 103.53 ? 362 LYS B CB    1 
ATOM   2782  C  CG    . LYS A 1 362 ? 369.189 369.704 306.079 1.00 107.23 ? 362 LYS B CG    1 
ATOM   2783  C  CD    . LYS A 1 362 ? 368.003 370.546 305.565 1.00 110.25 ? 362 LYS B CD    1 
ATOM   2784  C  CE    . LYS A 1 362 ? 366.683 369.799 305.667 1.00 114.65 ? 362 LYS B CE    1 
ATOM   2785  N  NZ    . LYS A 1 362 ? 365.545 370.631 305.190 1.00 110.98 ? 362 LYS B NZ    1 
ATOM   2786  N  N     . MET A 1 363 ? 373.761 370.883 307.068 1.00 119.60 ? 363 MET B N     1 
ATOM   2787  C  CA    . MET A 1 363 ? 374.919 371.695 306.727 1.00 113.61 ? 363 MET B CA    1 
ATOM   2788  C  C     . MET A 1 363 ? 375.749 371.961 307.974 1.00 113.10 ? 363 MET B C     1 
ATOM   2789  O  O     . MET A 1 363 ? 375.269 371.838 309.104 1.00 121.93 ? 363 MET B O     1 
ATOM   2790  C  CB    . MET A 1 363 ? 374.465 373.006 306.090 1.00 113.86 ? 363 MET B CB    1 
ATOM   2791  C  CG    . MET A 1 363 ? 374.673 373.106 304.599 1.00 118.74 ? 363 MET B CG    1 
ATOM   2792  S  SD    . MET A 1 363 ? 373.692 374.386 303.781 1.00 134.15 ? 363 MET B SD    1 
ATOM   2793  C  CE    . MET A 1 363 ? 373.637 375.717 304.977 1.00 121.94 ? 363 MET B CE    1 
ATOM   2794  N  N     . ALA A 1 364 ? 377.008 372.328 307.751 1.00 98.79  ? 364 ALA B N     1 
ATOM   2795  C  CA    . ALA A 1 364 ? 377.900 372.726 308.830 1.00 99.67  ? 364 ALA B CA    1 
ATOM   2796  C  C     . ALA A 1 364 ? 379.131 373.374 308.219 1.00 104.75 ? 364 ALA B C     1 
ATOM   2797  O  O     . ALA A 1 364 ? 379.432 373.164 307.044 1.00 114.21 ? 364 ALA B O     1 
ATOM   2798  C  CB    . ALA A 1 364 ? 378.305 371.530 309.700 1.00 104.86 ? 364 ALA B CB    1 
ATOM   2799  N  N     . VAL A 1 365 ? 379.835 374.161 309.025 1.00 110.91 ? 365 VAL B N     1 
ATOM   2800  C  CA    . VAL A 1 365 ? 381.087 374.783 308.617 1.00 110.87 ? 365 VAL B CA    1 
ATOM   2801  C  C     . VAL A 1 365 ? 381.969 374.945 309.846 1.00 112.74 ? 365 VAL B C     1 
ATOM   2802  O  O     . VAL A 1 365 ? 381.485 375.289 310.932 1.00 117.11 ? 365 VAL B O     1 
ATOM   2803  C  CB    . VAL A 1 365 ? 380.856 376.138 307.906 1.00 114.10 ? 365 VAL B CB    1 
ATOM   2804  C  CG1   . VAL A 1 365 ? 380.008 377.088 308.750 1.00 113.64 ? 365 VAL B CG1   1 
ATOM   2805  C  CG2   . VAL A 1 365 ? 382.184 376.792 307.545 1.00 113.13 ? 365 VAL B CG2   1 
ATOM   2806  N  N     . THR A 1 366 ? 383.264 374.694 309.663 1.00 107.19 ? 366 THR B N     1 
ATOM   2807  C  CA    . THR A 1 366 ? 384.277 374.834 310.697 1.00 104.54 ? 366 THR B CA    1 
ATOM   2808  C  C     . THR A 1 366 ? 385.296 375.866 310.242 1.00 101.79 ? 366 THR B C     1 
ATOM   2809  O  O     . THR A 1 366 ? 385.832 375.775 309.132 1.00 111.17 ? 366 THR B O     1 
ATOM   2810  C  CB    . THR A 1 366 ? 384.950 373.494 310.983 1.00 103.29 ? 366 THR B CB    1 
ATOM   2811  O  OG1   . THR A 1 366 ? 383.944 372.541 311.337 1.00 110.50 ? 366 THR B OG1   1 
ATOM   2812  C  CG2   . THR A 1 366 ? 385.956 373.617 312.121 1.00 105.21 ? 366 THR B CG2   1 
ATOM   2813  N  N     . PHE A 1 367 ? 385.556 376.832 311.110 1.00 91.94  ? 367 PHE B N     1 
ATOM   2814  C  CA    . PHE A 1 367 ? 386.361 378.007 310.825 1.00 94.39  ? 367 PHE B CA    1 
ATOM   2815  C  C     . PHE A 1 367 ? 387.694 377.884 311.541 1.00 100.55 ? 367 PHE B C     1 
ATOM   2816  O  O     . PHE A 1 367 ? 387.741 377.404 312.673 1.00 110.73 ? 367 PHE B O     1 
ATOM   2817  C  CB    . PHE A 1 367 ? 385.620 379.253 311.304 1.00 97.87  ? 367 PHE B CB    1 
ATOM   2818  C  CG    . PHE A 1 367 ? 386.271 380.538 310.924 1.00 102.52 ? 367 PHE B CG    1 
ATOM   2819  C  CD1   . PHE A 1 367 ? 385.994 381.130 309.714 1.00 108.62 ? 367 PHE B CD1   1 
ATOM   2820  C  CD2   . PHE A 1 367 ? 387.142 381.173 311.793 1.00 98.89  ? 367 PHE B CD2   1 
ATOM   2821  C  CE1   . PHE A 1 367 ? 386.574 382.320 309.370 1.00 110.63 ? 367 PHE B CE1   1 
ATOM   2822  C  CE2   . PHE A 1 367 ? 387.734 382.365 311.448 1.00 98.98  ? 367 PHE B CE2   1 
ATOM   2823  C  CZ    . PHE A 1 367 ? 387.450 382.940 310.232 1.00 108.38 ? 367 PHE B CZ    1 
ATOM   2824  N  N     . ILE A 1 368 ? 388.769 378.311 310.879 1.00 94.02  ? 368 ILE B N     1 
ATOM   2825  C  CA    . ILE A 1 368 ? 390.098 378.405 311.480 1.00 88.35  ? 368 ILE B CA    1 
ATOM   2826  C  C     . ILE A 1 368 ? 390.689 379.736 311.042 1.00 92.42  ? 368 ILE B C     1 
ATOM   2827  O  O     . ILE A 1 368 ? 390.986 379.916 309.855 1.00 101.57 ? 368 ILE B O     1 
ATOM   2828  C  CB    . ILE A 1 368 ? 391.019 377.242 311.060 1.00 90.00  ? 368 ILE B CB    1 
ATOM   2829  C  CG1   . ILE A 1 368 ? 390.339 375.883 311.291 1.00 93.85  ? 368 ILE B CG1   1 
ATOM   2830  C  CG2   . ILE A 1 368 ? 392.363 377.304 311.816 1.00 95.36  ? 368 ILE B CG2   1 
ATOM   2831  C  CD1   . ILE A 1 368 ? 389.635 375.326 310.066 1.00 103.17 ? 368 ILE B CD1   1 
ATOM   2832  N  N     . GLY A 1 369 ? 390.882 380.656 311.991 1.00 99.15  ? 369 GLY B N     1 
ATOM   2833  C  CA    . GLY A 1 369 ? 391.422 381.973 311.696 1.00 104.03 ? 369 GLY B CA    1 
ATOM   2834  C  C     . GLY A 1 369 ? 392.784 382.218 312.310 1.00 106.70 ? 369 GLY B C     1 
ATOM   2835  O  O     . GLY A 1 369 ? 392.913 382.233 313.536 1.00 112.94 ? 369 GLY B O     1 
ATOM   2836  N  N     . ASN A 1 370 ? 393.812 382.375 311.476 1.00 94.90  ? 370 ASN B N     1 
ATOM   2837  C  CA    . ASN A 1 370 ? 395.117 382.862 311.916 1.00 88.14  ? 370 ASN B CA    1 
ATOM   2838  C  C     . ASN A 1 370 ? 395.088 384.377 311.778 1.00 94.12  ? 370 ASN B C     1 
ATOM   2839  O  O     . ASN A 1 370 ? 395.211 384.913 310.671 1.00 101.92 ? 370 ASN B O     1 
ATOM   2840  C  CB    . ASN A 1 370 ? 396.236 382.243 311.088 1.00 90.08  ? 370 ASN B CB    1 
ATOM   2841  C  CG    . ASN A 1 370 ? 397.606 382.498 311.678 1.00 94.09  ? 370 ASN B CG    1 
ATOM   2842  O  OD1   . ASN A 1 370 ? 397.750 383.243 312.645 1.00 100.60 ? 370 ASN B OD1   1 
ATOM   2843  N  ND2   . ASN A 1 370 ? 398.624 381.883 311.091 1.00 104.06 ? 370 ASN B ND2   1 
ATOM   2844  N  N     . SER A 1 371 ? 394.906 385.062 312.909 1.00 99.45  ? 371 SER B N     1 
ATOM   2845  C  CA    . SER A 1 371 ? 394.770 386.509 312.971 1.00 100.70 ? 371 SER B CA    1 
ATOM   2846  C  C     . SER A 1 371 ? 395.708 387.065 314.030 1.00 97.09  ? 371 SER B C     1 
ATOM   2847  O  O     . SER A 1 371 ? 396.101 386.364 314.965 1.00 98.43  ? 371 SER B O     1 
ATOM   2848  C  CB    . SER A 1 371 ? 393.334 386.925 313.298 1.00 98.57  ? 371 SER B CB    1 
ATOM   2849  O  OG    . SER A 1 371 ? 393.109 386.905 314.695 1.00 98.24  ? 371 SER B OG    1 
ATOM   2850  N  N     . THR A 1 372 ? 396.053 388.341 313.876 1.00 100.02 ? 372 THR B N     1 
ATOM   2851  C  CA    . THR A 1 372 ? 396.977 389.000 314.789 1.00 99.13  ? 372 THR B CA    1 
ATOM   2852  C  C     . THR A 1 372 ? 396.341 389.386 316.121 1.00 103.96 ? 372 THR B C     1 
ATOM   2853  O  O     . THR A 1 372 ? 397.058 389.856 317.010 1.00 108.16 ? 372 THR B O     1 
ATOM   2854  C  CB    . THR A 1 372 ? 397.560 390.249 314.127 1.00 102.01 ? 372 THR B CB    1 
ATOM   2855  O  OG1   . THR A 1 372 ? 396.500 391.143 313.768 1.00 110.00 ? 372 THR B OG1   1 
ATOM   2856  C  CG2   . THR A 1 372 ? 398.348 389.874 312.880 1.00 102.42 ? 372 THR B CG2   1 
ATOM   2857  N  N     . ALA A 1 373 ? 395.028 389.202 316.290 1.00 105.60 ? 373 ALA B N     1 
ATOM   2858  C  CA    . ALA A 1 373 ? 394.389 389.530 317.559 1.00 104.68 ? 373 ALA B CA    1 
ATOM   2859  C  C     . ALA A 1 373 ? 394.799 388.592 318.691 1.00 107.52 ? 373 ALA B C     1 
ATOM   2860  O  O     . ALA A 1 373 ? 394.581 388.926 319.859 1.00 116.09 ? 373 ALA B O     1 
ATOM   2861  C  CB    . ALA A 1 373 ? 392.869 389.510 317.399 1.00 105.94 ? 373 ALA B CB    1 
ATOM   2862  N  N     . ILE A 1 374 ? 395.391 387.434 318.380 1.00 101.36 ? 374 ILE B N     1 
ATOM   2863  C  CA    . ILE A 1 374 ? 395.907 386.543 319.414 1.00 101.22 ? 374 ILE B CA    1 
ATOM   2864  C  C     . ILE A 1 374 ? 397.084 387.166 320.169 1.00 103.07 ? 374 ILE B C     1 
ATOM   2865  O  O     . ILE A 1 374 ? 397.411 386.727 321.286 1.00 106.18 ? 374 ILE B O     1 
ATOM   2866  C  CB    . ILE A 1 374 ? 396.282 385.194 318.766 1.00 100.93 ? 374 ILE B CB    1 
ATOM   2867  C  CG1   . ILE A 1 374 ? 396.322 384.068 319.805 1.00 102.88 ? 374 ILE B CG1   1 
ATOM   2868  C  CG2   . ILE A 1 374 ? 397.604 385.295 318.017 1.00 106.43 ? 374 ILE B CG2   1 
ATOM   2869  C  CD1   . ILE A 1 374 ? 394.955 383.505 320.145 1.00 100.35 ? 374 ILE B CD1   1 
ATOM   2870  N  N     . GLN A 1 375 ? 397.732 388.184 319.586 1.00 103.38 ? 375 GLN B N     1 
ATOM   2871  C  CA    . GLN A 1 375 ? 398.759 388.929 320.303 1.00 101.72 ? 375 GLN B CA    1 
ATOM   2872  C  C     . GLN A 1 375 ? 398.214 389.562 321.576 1.00 109.39 ? 375 GLN B C     1 
ATOM   2873  O  O     . GLN A 1 375 ? 398.962 389.742 322.535 1.00 113.60 ? 375 GLN B O     1 
ATOM   2874  C  CB    . GLN A 1 375 ? 399.365 390.001 319.390 1.00 102.19 ? 375 GLN B CB    1 
ATOM   2875  C  CG    . GLN A 1 375 ? 398.584 391.315 319.323 1.00 105.41 ? 375 GLN B CG    1 
ATOM   2876  C  CD    . GLN A 1 375 ? 398.961 392.166 318.129 1.00 114.45 ? 375 GLN B CD    1 
ATOM   2877  O  OE1   . GLN A 1 375 ? 399.885 391.842 317.382 1.00 121.16 ? 375 GLN B OE1   1 
ATOM   2878  N  NE2   . GLN A 1 375 ? 398.245 393.265 317.942 1.00 114.16 ? 375 GLN B NE2   1 
ATOM   2879  N  N     . GLU A 1 376 ? 396.922 389.903 321.612 1.00 119.25 ? 376 GLU B N     1 
ATOM   2880  C  CA    . GLU A 1 376 ? 396.341 390.447 322.837 1.00 117.87 ? 376 GLU B CA    1 
ATOM   2881  C  C     . GLU A 1 376 ? 396.335 389.406 323.951 1.00 115.42 ? 376 GLU B C     1 
ATOM   2882  O  O     . GLU A 1 376 ? 396.676 389.714 325.100 1.00 121.43 ? 376 GLU B O     1 
ATOM   2883  C  CB    . GLU A 1 376 ? 394.921 390.954 322.572 1.00 116.75 ? 376 GLU B CB    1 
ATOM   2884  C  CG    . GLU A 1 376 ? 394.777 391.904 321.378 1.00 120.57 ? 376 GLU B CG    1 
ATOM   2885  C  CD    . GLU A 1 376 ? 395.745 393.072 321.423 1.00 123.73 ? 376 GLU B CD    1 
ATOM   2886  O  OE1   . GLU A 1 376 ? 396.021 393.575 322.533 1.00 122.63 ? 376 GLU B OE1   1 
ATOM   2887  O  OE2   . GLU A 1 376 ? 396.233 393.484 320.350 1.00 119.69 ? 376 GLU B OE2   1 
ATOM   2888  N  N     . LEU A 1 377 ? 395.956 388.167 323.630 1.00 102.68 ? 377 LEU B N     1 
ATOM   2889  C  CA    . LEU A 1 377 ? 395.998 387.097 324.624 1.00 107.00 ? 377 LEU B CA    1 
ATOM   2890  C  C     . LEU A 1 377 ? 397.423 386.827 325.085 1.00 110.04 ? 377 LEU B C     1 
ATOM   2891  O  O     . LEU A 1 377 ? 397.670 386.630 326.284 1.00 107.13 ? 377 LEU B O     1 
ATOM   2892  C  CB    . LEU A 1 377 ? 395.373 385.829 324.045 1.00 102.46 ? 377 LEU B CB    1 
ATOM   2893  C  CG    . LEU A 1 377 ? 395.507 384.522 324.831 1.00 101.31 ? 377 LEU B CG    1 
ATOM   2894  C  CD1   . LEU A 1 377 ? 394.177 383.785 324.839 1.00 108.37 ? 377 LEU B CD1   1 
ATOM   2895  C  CD2   . LEU A 1 377 ? 396.611 383.654 324.238 1.00 98.59  ? 377 LEU B CD2   1 
ATOM   2896  N  N     . PHE A 1 378 ? 398.373 386.796 324.148 1.00 108.84 ? 378 PHE B N     1 
ATOM   2897  C  CA    . PHE A 1 378 ? 399.759 386.564 324.547 1.00 100.71 ? 378 PHE B CA    1 
ATOM   2898  C  C     . PHE A 1 378 ? 400.293 387.719 325.383 1.00 103.16 ? 378 PHE B C     1 
ATOM   2899  O  O     . PHE A 1 378 ? 401.060 387.504 326.328 1.00 104.61 ? 378 PHE B O     1 
ATOM   2900  C  CB    . PHE A 1 378 ? 400.637 386.331 323.317 1.00 103.86 ? 378 PHE B CB    1 
ATOM   2901  C  CG    . PHE A 1 378 ? 400.407 385.003 322.653 1.00 103.30 ? 378 PHE B CG    1 
ATOM   2902  C  CD1   . PHE A 1 378 ? 400.723 383.821 323.304 1.00 100.50 ? 378 PHE B CD1   1 
ATOM   2903  C  CD2   . PHE A 1 378 ? 399.871 384.936 321.382 1.00 106.42 ? 378 PHE B CD2   1 
ATOM   2904  C  CE1   . PHE A 1 378 ? 400.507 382.607 322.700 1.00 101.92 ? 378 PHE B CE1   1 
ATOM   2905  C  CE2   . PHE A 1 378 ? 399.654 383.720 320.776 1.00 105.35 ? 378 PHE B CE2   1 
ATOM   2906  C  CZ    . PHE A 1 378 ? 399.973 382.558 321.436 1.00 103.99 ? 378 PHE B CZ    1 
ATOM   2907  N  N     . LYS A 1 379 ? 399.880 388.947 325.064 1.00 111.76 ? 379 LYS B N     1 
ATOM   2908  C  CA    . LYS A 1 379 ? 400.247 390.102 325.871 1.00 112.36 ? 379 LYS B CA    1 
ATOM   2909  C  C     . LYS A 1 379 ? 399.697 389.969 327.282 1.00 115.11 ? 379 LYS B C     1 
ATOM   2910  O  O     . LYS A 1 379 ? 400.395 390.265 328.256 1.00 118.41 ? 379 LYS B O     1 
ATOM   2911  C  CB    . LYS A 1 379 ? 399.722 391.377 325.205 1.00 112.58 ? 379 LYS B CB    1 
ATOM   2912  C  CG    . LYS A 1 379 ? 400.120 392.696 325.879 1.00 115.97 ? 379 LYS B CG    1 
ATOM   2913  C  CD    . LYS A 1 379 ? 399.428 393.893 325.230 1.00 114.16 ? 379 LYS B CD    1 
ATOM   2914  C  CE    . LYS A 1 379 ? 399.905 394.151 323.807 1.00 119.05 ? 379 LYS B CE    1 
ATOM   2915  N  NZ    . LYS A 1 379 ? 399.006 393.513 322.806 1.00 120.58 ? 379 LYS B NZ    1 
ATOM   2916  N  N     . ARG A 1 380 ? 398.446 389.527 327.406 1.00 104.46 ? 380 ARG B N     1 
ATOM   2917  C  CA    . ARG A 1 380 ? 397.837 389.357 328.721 1.00 100.70 ? 380 ARG B CA    1 
ATOM   2918  C  C     . ARG A 1 380 ? 398.579 388.309 329.541 1.00 101.39 ? 380 ARG B C     1 
ATOM   2919  O  O     . ARG A 1 380 ? 398.870 388.517 330.727 1.00 106.33 ? 380 ARG B O     1 
ATOM   2920  C  CB    . ARG A 1 380 ? 396.370 388.967 328.555 1.00 103.91 ? 380 ARG B CB    1 
ATOM   2921  C  CG    . ARG A 1 380 ? 395.661 388.616 329.848 1.00 105.47 ? 380 ARG B CG    1 
ATOM   2922  C  CD    . ARG A 1 380 ? 394.161 388.615 329.662 1.00 107.14 ? 380 ARG B CD    1 
ATOM   2923  N  NE    . ARG A 1 380 ? 393.740 387.618 328.683 1.00 109.05 ? 380 ARG B NE    1 
ATOM   2924  C  CZ    . ARG A 1 380 ? 393.723 386.303 328.877 1.00 111.13 ? 380 ARG B CZ    1 
ATOM   2925  N  NH1   . ARG A 1 380 ? 394.128 385.756 330.015 1.00 105.06 ? 380 ARG B NH1   1 
ATOM   2926  N  NH2   . ARG A 1 380 ? 393.293 385.511 327.900 1.00 106.97 ? 380 ARG B NH2   1 
ATOM   2927  N  N     . ILE A 1 381 ? 398.888 387.167 328.921 1.00 98.22  ? 381 ILE B N     1 
ATOM   2928  C  CA    . ILE A 1 381 ? 399.566 386.099 329.650 1.00 101.72 ? 381 ILE B CA    1 
ATOM   2929  C  C     . ILE A 1 381 ? 400.970 386.536 330.045 1.00 107.98 ? 381 ILE B C     1 
ATOM   2930  O  O     . ILE A 1 381 ? 401.423 386.264 331.162 1.00 109.99 ? 381 ILE B O     1 
ATOM   2931  C  CB    . ILE A 1 381 ? 399.581 384.796 328.826 1.00 102.29 ? 381 ILE B CB    1 
ATOM   2932  C  CG1   . ILE A 1 381 ? 398.165 384.223 328.687 1.00 103.57 ? 381 ILE B CG1   1 
ATOM   2933  C  CG2   . ILE A 1 381 ? 400.492 383.749 329.478 1.00 102.30 ? 381 ILE B CG2   1 
ATOM   2934  C  CD1   . ILE A 1 381 ? 397.986 383.304 327.500 1.00 107.84 ? 381 ILE B CD1   1 
ATOM   2935  N  N     . SER A 1 382 ? 401.677 387.230 329.149 1.00 119.02 ? 382 SER B N     1 
ATOM   2936  C  CA    . SER A 1 382 ? 403.013 387.709 329.484 1.00 113.97 ? 382 SER B CA    1 
ATOM   2937  C  C     . SER A 1 382 ? 402.965 388.767 330.579 1.00 116.69 ? 382 SER B C     1 
ATOM   2938  O  O     . SER A 1 382 ? 403.857 388.822 331.431 1.00 121.71 ? 382 SER B O     1 
ATOM   2939  C  CB    . SER A 1 382 ? 403.703 388.255 328.235 1.00 117.41 ? 382 SER B CB    1 
ATOM   2940  O  OG    . SER A 1 382 ? 402.896 389.213 327.576 1.00 125.21 ? 382 SER B OG    1 
ATOM   2941  N  N     . GLU A 1 383 ? 401.935 389.616 330.577 1.00 109.62 ? 383 GLU B N     1 
ATOM   2942  C  CA    . GLU A 1 383 ? 401.808 390.623 331.624 1.00 109.81 ? 383 GLU B CA    1 
ATOM   2943  C  C     . GLU A 1 383 ? 401.561 389.977 332.980 1.00 109.86 ? 383 GLU B C     1 
ATOM   2944  O  O     . GLU A 1 383 ? 402.171 390.374 333.980 1.00 112.43 ? 383 GLU B O     1 
ATOM   2945  C  CB    . GLU A 1 383 ? 400.682 391.599 331.278 1.00 109.84 ? 383 GLU B CB    1 
ATOM   2946  C  CG    . GLU A 1 383 ? 400.835 392.995 331.883 1.00 113.99 ? 383 GLU B CG    1 
ATOM   2947  C  CD    . GLU A 1 383 ? 400.462 393.058 333.353 1.00 115.76 ? 383 GLU B CD    1 
ATOM   2948  O  OE1   . GLU A 1 383 ? 399.445 392.448 333.745 1.00 113.53 ? 383 GLU B OE1   1 
ATOM   2949  O  OE2   . GLU A 1 383 ? 401.191 393.721 334.121 1.00 113.76 ? 383 GLU B OE2   1 
ATOM   2950  N  N     . GLN A 1 384 ? 400.671 388.981 333.034 1.00 98.77  ? 384 GLN B N     1 
ATOM   2951  C  CA    . GLN A 1 384 ? 400.441 388.268 334.289 1.00 91.59  ? 384 GLN B CA    1 
ATOM   2952  C  C     . GLN A 1 384 ? 401.700 387.539 334.741 1.00 94.76  ? 384 GLN B C     1 
ATOM   2953  O  O     . GLN A 1 384 ? 402.034 387.529 335.937 1.00 103.84 ? 384 GLN B O     1 
ATOM   2954  C  CB    . GLN A 1 384 ? 399.284 387.284 334.123 1.00 92.67  ? 384 GLN B CB    1 
ATOM   2955  C  CG    . GLN A 1 384 ? 397.933 387.951 333.930 1.00 97.87  ? 384 GLN B CG    1 
ATOM   2956  C  CD    . GLN A 1 384 ? 396.809 386.952 333.753 1.00 103.14 ? 384 GLN B CD    1 
ATOM   2957  O  OE1   . GLN A 1 384 ? 397.041 385.747 333.667 1.00 105.36 ? 384 GLN B OE1   1 
ATOM   2958  N  NE2   . GLN A 1 384 ? 395.580 387.449 333.696 1.00 102.97 ? 384 GLN B NE2   1 
ATOM   2959  N  N     . PHE A 1 385 ? 402.419 386.939 333.788 1.00 100.61 ? 385 PHE B N     1 
ATOM   2960  C  CA    . PHE A 1 385 ? 403.666 386.252 334.095 1.00 101.86 ? 385 PHE B CA    1 
ATOM   2961  C  C     . PHE A 1 385 ? 404.684 387.211 334.690 1.00 104.44 ? 385 PHE B C     1 
ATOM   2962  O  O     . PHE A 1 385 ? 405.340 386.891 335.682 1.00 113.12 ? 385 PHE B O     1 
ATOM   2963  C  CB    . PHE A 1 385 ? 404.217 385.602 332.824 1.00 103.72 ? 385 PHE B CB    1 
ATOM   2964  C  CG    . PHE A 1 385 ? 405.471 384.803 333.038 1.00 99.10  ? 385 PHE B CG    1 
ATOM   2965  C  CD1   . PHE A 1 385 ? 405.402 383.469 333.390 1.00 103.61 ? 385 PHE B CD1   1 
ATOM   2966  C  CD2   . PHE A 1 385 ? 406.719 385.378 332.863 1.00 94.58  ? 385 PHE B CD2   1 
ATOM   2967  C  CE1   . PHE A 1 385 ? 406.549 382.735 333.582 1.00 103.83 ? 385 PHE B CE1   1 
ATOM   2968  C  CE2   . PHE A 1 385 ? 407.861 384.647 333.062 1.00 96.70  ? 385 PHE B CE2   1 
ATOM   2969  C  CZ    . PHE A 1 385 ? 407.779 383.327 333.410 1.00 104.57 ? 385 PHE B CZ    1 
ATOM   2970  N  N     . THR A 1 386 ? 404.833 388.393 334.093 1.00 101.92 ? 386 THR B N     1 
ATOM   2971  C  CA    . THR A 1 386 ? 405.803 389.355 334.601 1.00 100.53 ? 386 THR B CA    1 
ATOM   2972  C  C     . THR A 1 386 ? 405.381 389.894 335.960 1.00 103.69 ? 386 THR B C     1 
ATOM   2973  O  O     . THR A 1 386 ? 406.228 390.110 336.834 1.00 108.04 ? 386 THR B O     1 
ATOM   2974  C  CB    . THR A 1 386 ? 405.980 390.501 333.608 1.00 105.17 ? 386 THR B CB    1 
ATOM   2975  O  OG1   . THR A 1 386 ? 404.698 390.915 333.125 1.00 107.18 ? 386 THR B OG1   1 
ATOM   2976  C  CG2   . THR A 1 386 ? 406.844 390.061 332.438 1.00 109.44 ? 386 THR B CG2   1 
ATOM   2977  N  N     . ALA A 1 387 ? 404.077 390.106 336.157 1.00 101.02 ? 387 ALA B N     1 
ATOM   2978  C  CA    . ALA A 1 387 ? 403.589 390.605 337.438 1.00 100.51 ? 387 ALA B CA    1 
ATOM   2979  C  C     . ALA A 1 387 ? 403.880 389.619 338.560 1.00 95.58  ? 387 ALA B C     1 
ATOM   2980  O  O     . ALA A 1 387 ? 404.271 390.023 339.661 1.00 96.24  ? 387 ALA B O     1 
ATOM   2981  C  CB    . ALA A 1 387 ? 402.091 390.891 337.353 1.00 97.53  ? 387 ALA B CB    1 
ATOM   2982  N  N     . MET A 1 388 ? 403.702 388.321 338.302 1.00 92.76  ? 388 MET B N     1 
ATOM   2983  C  CA    . MET A 1 388 ? 404.047 387.333 339.325 1.00 90.28  ? 388 MET B CA    1 
ATOM   2984  C  C     . MET A 1 388 ? 405.559 387.165 339.454 1.00 95.81  ? 388 MET B C     1 
ATOM   2985  O  O     . MET A 1 388 ? 406.084 387.045 340.567 1.00 107.63 ? 388 MET B O     1 
ATOM   2986  C  CB    . MET A 1 388 ? 403.394 385.989 339.014 1.00 92.04  ? 388 MET B CB    1 
ATOM   2987  C  CG    . MET A 1 388 ? 402.028 385.813 339.638 1.00 101.24 ? 388 MET B CG    1 
ATOM   2988  S  SD    . MET A 1 388 ? 401.000 384.669 338.714 1.00 103.88 ? 388 MET B SD    1 
ATOM   2989  C  CE    . MET A 1 388 ? 401.017 383.272 339.834 1.00 102.00 ? 388 MET B CE    1 
ATOM   2990  N  N     . PHE A 1 389 ? 406.276 387.165 338.331 1.00 95.39  ? 389 PHE B N     1 
ATOM   2991  C  CA    . PHE A 1 389 ? 407.702 386.872 338.329 1.00 93.84  ? 389 PHE B CA    1 
ATOM   2992  C  C     . PHE A 1 389 ? 408.526 387.998 338.936 1.00 94.24  ? 389 PHE B C     1 
ATOM   2993  O  O     . PHE A 1 389 ? 409.651 387.753 339.384 1.00 95.06  ? 389 PHE B O     1 
ATOM   2994  C  CB    . PHE A 1 389 ? 408.149 386.601 336.892 1.00 96.75  ? 389 PHE B CB    1 
ATOM   2995  C  CG    . PHE A 1 389 ? 409.588 386.213 336.764 1.00 94.94  ? 389 PHE B CG    1 
ATOM   2996  C  CD1   . PHE A 1 389 ? 410.013 384.966 337.174 1.00 91.14  ? 389 PHE B CD1   1 
ATOM   2997  C  CD2   . PHE A 1 389 ? 410.513 387.090 336.229 1.00 100.32 ? 389 PHE B CD2   1 
ATOM   2998  C  CE1   . PHE A 1 389 ? 411.330 384.598 337.055 1.00 93.84  ? 389 PHE B CE1   1 
ATOM   2999  C  CE2   . PHE A 1 389 ? 411.837 386.727 336.108 1.00 99.74  ? 389 PHE B CE2   1 
ATOM   3000  C  CZ    . PHE A 1 389 ? 412.246 385.478 336.523 1.00 96.08  ? 389 PHE B CZ    1 
ATOM   3001  N  N     . ARG A 1 390 ? 407.994 389.223 338.955 1.00 98.89  ? 390 ARG B N     1 
ATOM   3002  C  CA    . ARG A 1 390 ? 408.668 390.318 339.641 1.00 100.57 ? 390 ARG B CA    1 
ATOM   3003  C  C     . ARG A 1 390 ? 408.830 390.009 341.122 1.00 102.88 ? 390 ARG B C     1 
ATOM   3004  O  O     . ARG A 1 390 ? 409.892 390.254 341.705 1.00 101.14 ? 390 ARG B O     1 
ATOM   3005  C  CB    . ARG A 1 390 ? 407.870 391.605 339.442 1.00 103.67 ? 390 ARG B CB    1 
ATOM   3006  C  CG    . ARG A 1 390 ? 408.564 392.881 339.889 1.00 106.47 ? 390 ARG B CG    1 
ATOM   3007  C  CD    . ARG A 1 390 ? 407.631 394.074 339.748 1.00 104.25 ? 390 ARG B CD    1 
ATOM   3008  N  NE    . ARG A 1 390 ? 407.292 394.342 338.354 1.00 107.32 ? 390 ARG B NE    1 
ATOM   3009  C  CZ    . ARG A 1 390 ? 406.254 395.058 337.935 1.00 110.53 ? 390 ARG B CZ    1 
ATOM   3010  N  NH1   . ARG A 1 390 ? 405.406 395.628 338.781 1.00 114.56 ? 390 ARG B NH1   1 
ATOM   3011  N  NH2   . ARG A 1 390 ? 406.057 395.206 336.628 1.00 105.02 ? 390 ARG B NH2   1 
ATOM   3012  N  N     . ARG A 1 391 ? 407.786 389.463 341.741 1.00 95.06  ? 391 ARG B N     1 
ATOM   3013  C  CA    . ARG A 1 391 ? 407.815 389.049 343.136 1.00 91.94  ? 391 ARG B CA    1 
ATOM   3014  C  C     . ARG A 1 391 ? 408.286 387.613 343.342 1.00 93.12  ? 391 ARG B C     1 
ATOM   3015  O  O     . ARG A 1 391 ? 408.527 387.240 344.495 1.00 93.05  ? 391 ARG B O     1 
ATOM   3016  C  CB    . ARG A 1 391 ? 406.419 389.198 343.749 1.00 92.86  ? 391 ARG B CB    1 
ATOM   3017  C  CG    . ARG A 1 391 ? 405.917 390.635 343.836 1.00 89.75  ? 391 ARG B CG    1 
ATOM   3018  C  CD    . ARG A 1 391 ? 406.630 391.435 344.916 1.00 88.71  ? 391 ARG B CD    1 
ATOM   3019  N  NE    . ARG A 1 391 ? 405.898 392.664 345.223 1.00 94.51  ? 391 ARG B NE    1 
ATOM   3020  C  CZ    . ARG A 1 391 ? 405.665 393.173 346.431 1.00 100.47 ? 391 ARG B CZ    1 
ATOM   3021  N  NH1   . ARG A 1 391 ? 406.155 392.630 347.538 1.00 99.51  ? 391 ARG B NH1   1 
ATOM   3022  N  NH2   . ARG A 1 391 ? 404.924 394.272 346.533 1.00 97.80  ? 391 ARG B NH2   1 
ATOM   3023  N  N     . LYS A 1 392 ? 408.446 386.831 342.266 1.00 94.65  ? 392 LYS B N     1 
ATOM   3024  C  CA    . LYS A 1 392 ? 408.708 385.381 342.281 1.00 94.14  ? 392 LYS B CA    1 
ATOM   3025  C  C     . LYS A 1 392 ? 407.844 384.675 343.325 1.00 96.56  ? 392 LYS B C     1 
ATOM   3026  O  O     . LYS A 1 392 ? 408.328 384.073 344.283 1.00 105.18 ? 392 LYS B O     1 
ATOM   3027  C  CB    . LYS A 1 392 ? 410.197 385.057 342.473 1.00 93.78  ? 392 LYS B CB    1 
ATOM   3028  C  CG    . LYS A 1 392 ? 410.931 385.733 343.630 1.00 97.02  ? 392 LYS B CG    1 
ATOM   3029  C  CD    . LYS A 1 392 ? 412.327 385.148 343.895 1.00 99.85  ? 392 LYS B CD    1 
ATOM   3030  C  CE    . LYS A 1 392 ? 413.240 385.136 342.669 1.00 98.87  ? 392 LYS B CE    1 
ATOM   3031  N  NZ    . LYS A 1 392 ? 413.316 386.461 341.998 1.00 99.74  ? 392 LYS B NZ    1 
ATOM   3032  N  N     . ALA A 1 393 ? 406.531 384.774 343.109 1.00 102.17 ? 393 ALA B N     1 
ATOM   3033  C  CA    . ALA A 1 393 ? 405.566 384.358 344.120 1.00 110.13 ? 393 ALA B CA    1 
ATOM   3034  C  C     . ALA A 1 393 ? 405.608 382.854 344.355 1.00 111.58 ? 393 ALA B C     1 
ATOM   3035  O  O     . ALA A 1 393 ? 405.630 382.400 345.506 1.00 112.13 ? 393 ALA B O     1 
ATOM   3036  C  CB    . ALA A 1 393 ? 404.163 384.796 343.702 1.00 104.05 ? 393 ALA B CB    1 
ATOM   3037  N  N     . PHE A 1 394 ? 405.627 382.066 343.274 1.00 86.94  ? 394 PHE B N     1 
ATOM   3038  C  CA    . PHE A 1 394 ? 405.504 380.612 343.336 1.00 82.89  ? 394 PHE B CA    1 
ATOM   3039  C  C     . PHE A 1 394 ? 406.685 379.904 342.678 1.00 89.20  ? 394 PHE B C     1 
ATOM   3040  O  O     . PHE A 1 394 ? 406.569 378.733 342.305 1.00 95.85  ? 394 PHE B O     1 
ATOM   3041  C  CB    . PHE A 1 394 ? 404.193 380.175 342.679 1.00 85.82  ? 394 PHE B CB    1 
ATOM   3042  C  CG    . PHE A 1 394 ? 402.968 380.740 343.341 1.00 87.17  ? 394 PHE B CG    1 
ATOM   3043  C  CD1   . PHE A 1 394 ? 402.347 380.064 344.374 1.00 96.87  ? 394 PHE B CD1   1 
ATOM   3044  C  CD2   . PHE A 1 394 ? 402.431 381.944 342.920 1.00 85.70  ? 394 PHE B CD2   1 
ATOM   3045  C  CE1   . PHE A 1 394 ? 401.220 380.582 344.981 1.00 95.86  ? 394 PHE B CE1   1 
ATOM   3046  C  CE2   . PHE A 1 394 ? 401.306 382.465 343.522 1.00 84.16  ? 394 PHE B CE2   1 
ATOM   3047  C  CZ    . PHE A 1 394 ? 400.699 381.784 344.553 1.00 87.37  ? 394 PHE B CZ    1 
ATOM   3048  N  N     . LEU A 1 395 ? 407.827 380.581 342.535 1.00 90.76  ? 395 LEU B N     1 
ATOM   3049  C  CA    . LEU A 1 395 ? 408.959 379.972 341.846 1.00 93.72  ? 395 LEU B CA    1 
ATOM   3050  C  C     . LEU A 1 395 ? 409.636 378.884 342.665 1.00 97.44  ? 395 LEU B C     1 
ATOM   3051  O  O     . LEU A 1 395 ? 410.356 378.063 342.088 1.00 104.12 ? 395 LEU B O     1 
ATOM   3052  C  CB    . LEU A 1 395 ? 410.002 381.033 341.484 1.00 96.04  ? 395 LEU B CB    1 
ATOM   3053  C  CG    . LEU A 1 395 ? 409.701 382.097 340.423 1.00 101.87 ? 395 LEU B CG    1 
ATOM   3054  C  CD1   . LEU A 1 395 ? 410.974 382.858 340.108 1.00 104.46 ? 395 LEU B CD1   1 
ATOM   3055  C  CD2   . LEU A 1 395 ? 409.138 381.513 339.142 1.00 100.82 ? 395 LEU B CD2   1 
ATOM   3056  N  N     . HIS A 1 396 ? 409.455 378.867 343.987 1.00 91.01  ? 396 HIS B N     1 
ATOM   3057  C  CA    . HIS A 1 396 ? 410.139 377.860 344.789 1.00 91.66  ? 396 HIS B CA    1 
ATOM   3058  C  C     . HIS A 1 396 ? 409.588 376.465 344.522 1.00 92.08  ? 396 HIS B C     1 
ATOM   3059  O  O     . HIS A 1 396 ? 410.344 375.489 344.570 1.00 93.53  ? 396 HIS B O     1 
ATOM   3060  C  CB    . HIS A 1 396 ? 410.052 378.210 346.276 1.00 90.30  ? 396 HIS B CB    1 
ATOM   3061  C  CG    . HIS A 1 396 ? 408.667 378.159 346.838 1.00 88.61  ? 396 HIS B CG    1 
ATOM   3062  N  ND1   . HIS A 1 396 ? 408.207 377.092 347.578 1.00 86.91  ? 396 HIS B ND1   1 
ATOM   3063  C  CD2   . HIS A 1 396 ? 407.646 379.046 346.781 1.00 97.33  ? 396 HIS B CD2   1 
ATOM   3064  C  CE1   . HIS A 1 396 ? 406.961 377.322 347.950 1.00 89.26  ? 396 HIS B CE1   1 
ATOM   3065  N  NE2   . HIS A 1 396 ? 406.596 378.499 347.477 1.00 101.70 ? 396 HIS B NE2   1 
ATOM   3066  N  N     . TRP A 1 397 ? 408.294 376.352 344.205 1.00 88.78  ? 397 TRP B N     1 
ATOM   3067  C  CA    . TRP A 1 397 ? 407.735 375.059 343.822 1.00 81.78  ? 397 TRP B CA    1 
ATOM   3068  C  C     . TRP A 1 397 ? 408.385 374.530 342.551 1.00 86.03  ? 397 TRP B C     1 
ATOM   3069  O  O     . TRP A 1 397 ? 408.684 373.334 342.448 1.00 97.34  ? 397 TRP B O     1 
ATOM   3070  C  CB    . TRP A 1 397 ? 406.225 375.174 343.621 1.00 82.03  ? 397 TRP B CB    1 
ATOM   3071  C  CG    . TRP A 1 397 ? 405.456 375.434 344.870 1.00 85.89  ? 397 TRP B CG    1 
ATOM   3072  C  CD1   . TRP A 1 397 ? 404.694 376.527 345.150 1.00 87.54  ? 397 TRP B CD1   1 
ATOM   3073  C  CD2   . TRP A 1 397 ? 405.355 374.572 346.007 1.00 86.41  ? 397 TRP B CD2   1 
ATOM   3074  N  NE1   . TRP A 1 397 ? 404.130 376.404 346.394 1.00 90.77  ? 397 TRP B NE1   1 
ATOM   3075  C  CE2   . TRP A 1 397 ? 404.518 375.210 346.941 1.00 87.42  ? 397 TRP B CE2   1 
ATOM   3076  C  CE3   . TRP A 1 397 ? 405.892 373.323 346.327 1.00 90.30  ? 397 TRP B CE3   1 
ATOM   3077  C  CZ2   . TRP A 1 397 ? 404.211 374.646 348.174 1.00 92.60  ? 397 TRP B CZ2   1 
ATOM   3078  C  CZ3   . TRP A 1 397 ? 405.585 372.763 347.551 1.00 94.48  ? 397 TRP B CZ3   1 
ATOM   3079  C  CH2   . TRP A 1 397 ? 404.752 373.423 348.459 1.00 93.31  ? 397 TRP B CH2   1 
ATOM   3080  N  N     . TYR A 1 398 ? 408.607 375.405 341.571 1.00 91.92  ? 398 TYR B N     1 
ATOM   3081  C  CA    . TYR A 1 398 ? 409.205 374.972 340.313 1.00 100.63 ? 398 TYR B CA    1 
ATOM   3082  C  C     . TYR A 1 398 ? 410.692 374.690 340.482 1.00 99.91  ? 398 TYR B C     1 
ATOM   3083  O  O     . TYR A 1 398 ? 411.233 373.777 339.848 1.00 104.25 ? 398 TYR B O     1 
ATOM   3084  C  CB    . TYR A 1 398 ? 408.977 376.030 339.234 1.00 96.07  ? 398 TYR B CB    1 
ATOM   3085  C  CG    . TYR A 1 398 ? 407.527 376.198 338.831 1.00 94.57  ? 398 TYR B CG    1 
ATOM   3086  C  CD1   . TYR A 1 398 ? 406.649 376.937 339.612 1.00 93.88  ? 398 TYR B CD1   1 
ATOM   3087  C  CD2   . TYR A 1 398 ? 407.039 375.626 337.667 1.00 98.85  ? 398 TYR B CD2   1 
ATOM   3088  C  CE1   . TYR A 1 398 ? 405.330 377.091 339.252 1.00 92.81  ? 398 TYR B CE1   1 
ATOM   3089  C  CE2   . TYR A 1 398 ? 405.719 375.778 337.298 1.00 97.60  ? 398 TYR B CE2   1 
ATOM   3090  C  CZ    . TYR A 1 398 ? 404.871 376.511 338.095 1.00 93.83  ? 398 TYR B CZ    1 
ATOM   3091  O  OH    . TYR A 1 398 ? 403.555 376.667 337.734 1.00 101.17 ? 398 TYR B OH    1 
ATOM   3092  N  N     . THR A 1 399 ? 411.369 375.463 341.333 1.00 89.81  ? 399 THR B N     1 
ATOM   3093  C  CA    . THR A 1 399 ? 412.791 375.240 341.561 1.00 84.43  ? 399 THR B CA    1 
ATOM   3094  C  C     . THR A 1 399 ? 413.037 373.978 342.377 1.00 89.59  ? 399 THR B C     1 
ATOM   3095  O  O     . THR A 1 399 ? 414.090 373.348 342.232 1.00 91.88  ? 399 THR B O     1 
ATOM   3096  C  CB    . THR A 1 399 ? 413.408 376.449 342.263 1.00 85.47  ? 399 THR B CB    1 
ATOM   3097  O  OG1   . THR A 1 399 ? 413.086 377.643 341.539 1.00 85.99  ? 399 THR B OG1   1 
ATOM   3098  C  CG2   . THR A 1 399 ? 414.923 376.309 342.356 1.00 89.23  ? 399 THR B CG2   1 
ATOM   3099  N  N     . GLY A 1 400 ? 412.094 373.601 343.244 1.00 98.48  ? 400 GLY B N     1 
ATOM   3100  C  CA    . GLY A 1 400 ? 412.239 372.360 343.982 1.00 100.08 ? 400 GLY B CA    1 
ATOM   3101  C  C     . GLY A 1 400 ? 412.257 371.142 343.083 1.00 99.98  ? 400 GLY B C     1 
ATOM   3102  O  O     . GLY A 1 400 ? 412.967 370.172 343.362 1.00 105.13 ? 400 GLY B O     1 
ATOM   3103  N  N     . GLU A 1 401 ? 411.492 371.176 341.994 1.00 106.00 ? 401 GLU B N     1 
ATOM   3104  C  CA    . GLU A 1 401 ? 411.434 370.080 341.038 1.00 112.39 ? 401 GLU B CA    1 
ATOM   3105  C  C     . GLU A 1 401 ? 412.526 370.156 339.971 1.00 114.21 ? 401 GLU B C     1 
ATOM   3106  O  O     . GLU A 1 401 ? 412.420 369.458 338.957 1.00 118.32 ? 401 GLU B O     1 
ATOM   3107  C  CB    . GLU A 1 401 ? 410.055 370.034 340.366 1.00 111.26 ? 401 GLU B CB    1 
ATOM   3108  C  CG    . GLU A 1 401 ? 408.846 369.950 341.311 1.00 111.58 ? 401 GLU B CG    1 
ATOM   3109  C  CD    . GLU A 1 401 ? 408.710 368.606 342.009 1.00 117.64 ? 401 GLU B CD    1 
ATOM   3110  O  OE1   . GLU A 1 401 ? 409.657 368.175 342.696 1.00 116.73 ? 401 GLU B OE1   1 
ATOM   3111  O  OE2   . GLU A 1 401 ? 407.644 367.973 341.867 1.00 116.81 ? 401 GLU B OE2   1 
ATOM   3112  N  N     . GLY A 1 402 ? 413.548 370.998 340.162 1.00 102.73 ? 402 GLY B N     1 
ATOM   3113  C  CA    . GLY A 1 402 ? 414.790 370.901 339.410 1.00 102.55 ? 402 GLY B CA    1 
ATOM   3114  C  C     . GLY A 1 402 ? 415.177 372.093 338.554 1.00 106.74 ? 402 GLY B C     1 
ATOM   3115  O  O     . GLY A 1 402 ? 416.366 372.409 338.456 1.00 112.09 ? 402 GLY B O     1 
ATOM   3116  N  N     . MET A 1 403 ? 414.211 372.763 337.930 1.00 105.01 ? 403 MET B N     1 
ATOM   3117  C  CA    . MET A 1 403 ? 414.554 373.740 336.903 1.00 105.14 ? 403 MET B CA    1 
ATOM   3118  C  C     . MET A 1 403 ? 415.109 375.011 337.548 1.00 102.01 ? 403 MET B C     1 
ATOM   3119  O  O     . MET A 1 403 ? 414.989 375.233 338.756 1.00 100.06 ? 403 MET B O     1 
ATOM   3120  C  CB    . MET A 1 403 ? 413.335 374.034 336.004 1.00 106.12 ? 403 MET B CB    1 
ATOM   3121  C  CG    . MET A 1 403 ? 412.571 375.384 336.201 1.00 108.98 ? 403 MET B CG    1 
ATOM   3122  S  SD    . MET A 1 403 ? 411.256 375.726 335.011 1.00 114.55 ? 403 MET B SD    1 
ATOM   3123  C  CE    . MET A 1 403 ? 410.337 374.207 334.985 1.00 104.26 ? 403 MET B CE    1 
ATOM   3124  N  N     . ASP A 1 404 ? 415.722 375.847 336.711 1.00 121.39 ? 404 ASP B N     1 
ATOM   3125  C  CA    . ASP A 1 404 ? 416.291 377.129 337.104 1.00 125.24 ? 404 ASP B CA    1 
ATOM   3126  C  C     . ASP A 1 404 ? 415.400 378.284 336.657 1.00 127.90 ? 404 ASP B C     1 
ATOM   3127  O  O     . ASP A 1 404 ? 414.607 378.169 335.721 1.00 131.78 ? 404 ASP B O     1 
ATOM   3128  C  CB    . ASP A 1 404 ? 417.690 377.299 336.507 1.00 126.16 ? 404 ASP B CB    1 
ATOM   3129  C  CG    . ASP A 1 404 ? 418.565 376.080 336.719 1.00 130.73 ? 404 ASP B CG    1 
ATOM   3130  O  OD1   . ASP A 1 404 ? 418.376 375.077 335.999 1.00 130.82 ? 404 ASP B OD1   1 
ATOM   3131  O  OD2   . ASP A 1 404 ? 419.439 376.123 337.609 1.00 129.82 ? 404 ASP B OD2   1 
ATOM   3132  N  N     . GLU A 1 405 ? 415.566 379.422 337.336 1.00 124.68 ? 405 GLU B N     1 
ATOM   3133  C  CA    . GLU A 1 405 ? 414.868 380.653 336.972 1.00 121.70 ? 405 GLU B CA    1 
ATOM   3134  C  C     . GLU A 1 405 ? 415.289 381.183 335.603 1.00 121.11 ? 405 GLU B C     1 
ATOM   3135  O  O     . GLU A 1 405 ? 414.550 381.976 334.990 1.00 121.80 ? 405 GLU B O     1 
ATOM   3136  C  CB    . GLU A 1 405 ? 415.140 381.714 338.039 1.00 121.98 ? 405 GLU B CB    1 
ATOM   3137  C  CG    . GLU A 1 405 ? 414.281 382.958 337.938 1.00 127.41 ? 405 GLU B CG    1 
ATOM   3138  C  CD    . GLU A 1 405 ? 414.519 383.919 339.083 1.00 131.35 ? 405 GLU B CD    1 
ATOM   3139  O  OE1   . GLU A 1 405 ? 415.388 383.627 339.931 1.00 128.50 ? 405 GLU B OE1   1 
ATOM   3140  O  OE2   . GLU A 1 405 ? 413.841 384.965 339.134 1.00 127.12 ? 405 GLU B OE2   1 
ATOM   3141  N  N     . MET A 1 406 ? 416.472 380.771 335.141 1.00 118.50 ? 406 MET B N     1 
ATOM   3142  C  CA    . MET A 1 406 ? 416.938 381.196 333.796 1.00 119.29 ? 406 MET B CA    1 
ATOM   3143  C  C     . MET A 1 406 ? 415.899 380.740 332.768 1.00 120.96 ? 406 MET B C     1 
ATOM   3144  O  O     . MET A 1 406 ? 415.575 381.531 331.861 1.00 124.99 ? 406 MET B O     1 
ATOM   3145  C  CB    . MET A 1 406 ? 418.302 380.579 333.470 1.00 121.18 ? 406 MET B CB    1 
ATOM   3146  C  CG    . MET A 1 406 ? 419.422 381.079 334.360 1.00 122.07 ? 406 MET B CG    1 
ATOM   3147  S  SD    . MET A 1 406 ? 419.655 382.871 334.241 1.00 133.73 ? 406 MET B SD    1 
ATOM   3148  C  CE    . MET A 1 406 ? 420.241 383.015 332.554 1.00 124.21 ? 406 MET B CE    1 
ATOM   3149  N  N     . GLU A 1 407 ? 415.382 379.518 332.925 1.00 116.43 ? 407 GLU B N     1 
ATOM   3150  C  CA    . GLU A 1 407 ? 414.335 379.002 332.002 1.00 119.11 ? 407 GLU B CA    1 
ATOM   3151  C  C     . GLU A 1 407 ? 413.158 379.983 331.982 1.00 121.06 ? 407 GLU B C     1 
ATOM   3152  O  O     . GLU A 1 407 ? 412.706 380.336 330.875 1.00 124.03 ? 407 GLU B O     1 
ATOM   3153  C  CB    . GLU A 1 407 ? 413.887 377.602 332.428 1.00 118.57 ? 407 GLU B CB    1 
ATOM   3154  C  CG    . GLU A 1 407 ? 412.744 377.055 331.592 1.00 122.91 ? 407 GLU B CG    1 
ATOM   3155  C  CD    . GLU A 1 407 ? 412.482 375.568 331.762 1.00 123.47 ? 407 GLU B CD    1 
ATOM   3156  O  OE1   . GLU A 1 407 ? 413.233 374.919 332.516 1.00 120.49 ? 407 GLU B OE1   1 
ATOM   3157  O  OE2   . GLU A 1 407 ? 411.525 375.064 331.142 1.00 122.74 ? 407 GLU B OE2   1 
ATOM   3158  N  N     . PHE A 1 408 ? 412.687 380.408 333.159 1.00 107.72 ? 408 PHE B N     1 
ATOM   3159  C  CA    . PHE A 1 408 ? 411.540 381.315 333.217 1.00 105.71 ? 408 PHE B CA    1 
ATOM   3160  C  C     . PHE A 1 408 ? 411.819 382.583 332.424 1.00 108.84 ? 408 PHE B C     1 
ATOM   3161  O  O     . PHE A 1 408 ? 410.979 383.046 331.638 1.00 113.09 ? 408 PHE B O     1 
ATOM   3162  C  CB    . PHE A 1 408 ? 411.204 381.681 334.668 1.00 105.89 ? 408 PHE B CB    1 
ATOM   3163  C  CG    . PHE A 1 408 ? 410.361 380.667 335.388 1.00 108.01 ? 408 PHE B CG    1 
ATOM   3164  C  CD1   . PHE A 1 408 ? 410.898 379.476 335.831 1.00 107.66 ? 408 PHE B CD1   1 
ATOM   3165  C  CD2   . PHE A 1 408 ? 409.024 380.922 335.635 1.00 115.06 ? 408 PHE B CD2   1 
ATOM   3166  C  CE1   . PHE A 1 408 ? 410.113 378.563 336.504 1.00 113.11 ? 408 PHE B CE1   1 
ATOM   3167  C  CE2   . PHE A 1 408 ? 408.238 380.009 336.296 1.00 115.48 ? 408 PHE B CE2   1 
ATOM   3168  C  CZ    . PHE A 1 408 ? 408.782 378.831 336.732 1.00 114.17 ? 408 PHE B CZ    1 
ATOM   3169  N  N     . THR A 1 409 ? 413.010 383.150 332.611 1.00 109.32 ? 409 THR B N     1 
ATOM   3170  C  CA    . THR A 1 409 ? 413.347 384.360 331.867 1.00 108.01 ? 409 THR B CA    1 
ATOM   3171  C  C     . THR A 1 409 ? 413.455 384.089 330.370 1.00 108.38 ? 409 THR B C     1 
ATOM   3172  O  O     . THR A 1 409 ? 413.078 384.945 329.559 1.00 109.71 ? 409 THR B O     1 
ATOM   3173  C  CB    . THR A 1 409 ? 414.648 384.964 332.371 1.00 107.57 ? 409 THR B CB    1 
ATOM   3174  O  OG1   . THR A 1 409 ? 415.713 384.054 332.115 1.00 111.24 ? 409 THR B OG1   1 
ATOM   3175  C  CG2   . THR A 1 409 ? 414.574 385.254 333.856 1.00 106.26 ? 409 THR B CG2   1 
ATOM   3176  N  N     . GLU A 1 410 ? 413.971 382.917 329.981 1.00 114.54 ? 410 GLU B N     1 
ATOM   3177  C  CA    . GLU A 1 410 ? 414.053 382.579 328.562 1.00 111.74 ? 410 GLU B CA    1 
ATOM   3178  C  C     . GLU A 1 410 ? 412.667 382.448 327.945 1.00 111.28 ? 410 GLU B C     1 
ATOM   3179  O  O     . GLU A 1 410 ? 412.440 382.889 326.812 1.00 114.45 ? 410 GLU B O     1 
ATOM   3180  C  CB    . GLU A 1 410 ? 414.836 381.282 328.366 1.00 113.53 ? 410 GLU B CB    1 
ATOM   3181  C  CG    . GLU A 1 410 ? 416.333 381.433 328.527 1.00 115.83 ? 410 GLU B CG    1 
ATOM   3182  C  CD    . GLU A 1 410 ? 417.029 380.106 328.737 1.00 121.71 ? 410 GLU B CD    1 
ATOM   3183  O  OE1   . GLU A 1 410 ? 417.013 379.600 329.878 1.00 119.98 ? 410 GLU B OE1   1 
ATOM   3184  O  OE2   . GLU A 1 410 ? 417.600 379.568 327.765 1.00 122.15 ? 410 GLU B OE2   1 
ATOM   3185  N  N     . ALA A 1 411 ? 411.731 381.828 328.669 1.00 109.47 ? 411 ALA B N     1 
ATOM   3186  C  CA    . ALA A 1 411 ? 410.362 381.726 328.175 1.00 111.52 ? 411 ALA B CA    1 
ATOM   3187  C  C     . ALA A 1 411 ? 409.731 383.104 328.030 1.00 112.73 ? 411 ALA B C     1 
ATOM   3188  O  O     . ALA A 1 411 ? 409.016 383.369 327.056 1.00 120.02 ? 411 ALA B O     1 
ATOM   3189  C  CB    . ALA A 1 411 ? 409.531 380.850 329.109 1.00 111.98 ? 411 ALA B CB    1 
ATOM   3190  N  N     . GLU A 1 412 ? 409.989 383.997 328.990 1.00 115.34 ? 412 GLU B N     1 
ATOM   3191  C  CA    . GLU A 1 412 ? 409.481 385.362 328.880 1.00 118.34 ? 412 GLU B CA    1 
ATOM   3192  C  C     . GLU A 1 412 ? 410.064 386.074 327.664 1.00 116.49 ? 412 GLU B C     1 
ATOM   3193  O  O     . GLU A 1 412 ? 409.346 386.776 326.940 1.00 113.66 ? 412 GLU B O     1 
ATOM   3194  C  CB    . GLU A 1 412 ? 409.801 386.138 330.159 1.00 121.16 ? 412 GLU B CB    1 
ATOM   3195  C  CG    . GLU A 1 412 ? 409.380 387.614 330.178 1.00 118.37 ? 412 GLU B CG    1 
ATOM   3196  C  CD    . GLU A 1 412 ? 407.912 387.824 329.854 1.00 121.52 ? 412 GLU B CD    1 
ATOM   3197  O  OE1   . GLU A 1 412 ? 407.103 386.916 330.132 1.00 123.06 ? 412 GLU B OE1   1 
ATOM   3198  O  OE2   . GLU A 1 412 ? 407.570 388.897 329.315 1.00 120.36 ? 412 GLU B OE2   1 
ATOM   3199  N  N     . SER A 1 413 ? 411.368 385.911 327.432 1.00 109.16 ? 413 SER B N     1 
ATOM   3200  C  CA    . SER A 1 413 ? 412.004 386.546 326.282 1.00 108.30 ? 413 SER B CA    1 
ATOM   3201  C  C     . SER A 1 413 ? 411.439 386.005 324.975 1.00 112.32 ? 413 SER B C     1 
ATOM   3202  O  O     . SER A 1 413 ? 411.215 386.762 324.021 1.00 116.74 ? 413 SER B O     1 
ATOM   3203  C  CB    . SER A 1 413 ? 413.515 386.334 326.340 1.00 109.14 ? 413 SER B CB    1 
ATOM   3204  O  OG    . SER A 1 413 ? 414.157 386.960 325.245 1.00 110.85 ? 413 SER B OG    1 
ATOM   3205  N  N     . ASN A 1 414 ? 411.197 384.695 324.913 1.00 115.84 ? 414 ASN B N     1 
ATOM   3206  C  CA    . ASN A 1 414 ? 410.626 384.119 323.704 1.00 116.77 ? 414 ASN B CA    1 
ATOM   3207  C  C     . ASN A 1 414 ? 409.192 384.590 323.489 1.00 115.25 ? 414 ASN B C     1 
ATOM   3208  O  O     . ASN A 1 414 ? 408.775 384.790 322.345 1.00 115.22 ? 414 ASN B O     1 
ATOM   3209  C  CB    . ASN A 1 414 ? 410.693 382.592 323.765 1.00 112.53 ? 414 ASN B CB    1 
ATOM   3210  C  CG    . ASN A 1 414 ? 410.603 381.941 322.392 1.00 114.09 ? 414 ASN B CG    1 
ATOM   3211  O  OD1   . ASN A 1 414 ? 410.914 382.554 321.373 1.00 116.06 ? 414 ASN B OD1   1 
ATOM   3212  N  ND2   . ASN A 1 414 ? 410.179 380.685 322.364 1.00 113.29 ? 414 ASN B ND2   1 
ATOM   3213  N  N     . MET A 1 415 ? 408.427 384.783 324.567 1.00 112.90 ? 415 MET B N     1 
ATOM   3214  C  CA    . MET A 1 415 ? 407.094 385.363 324.426 1.00 109.50 ? 415 MET B CA    1 
ATOM   3215  C  C     . MET A 1 415 ? 407.165 386.788 323.901 1.00 117.25 ? 415 MET B C     1 
ATOM   3216  O  O     . MET A 1 415 ? 406.328 387.202 323.088 1.00 122.50 ? 415 MET B O     1 
ATOM   3217  C  CB    . MET A 1 415 ? 406.362 385.361 325.761 1.00 117.54 ? 415 MET B CB    1 
ATOM   3218  C  CG    . MET A 1 415 ? 406.012 383.988 326.294 1.00 122.99 ? 415 MET B CG    1 
ATOM   3219  S  SD    . MET A 1 415 ? 404.279 383.485 326.158 1.00 132.53 ? 415 MET B SD    1 
ATOM   3220  C  CE    . MET A 1 415 ? 403.350 384.834 326.881 1.00 119.78 ? 415 MET B CE    1 
ATOM   3221  N  N     . ASN A 1 416 ? 408.133 387.562 324.395 1.00 121.39 ? 416 ASN B N     1 
ATOM   3222  C  CA    . ASN A 1 416 ? 408.306 388.927 323.914 1.00 123.37 ? 416 ASN B CA    1 
ATOM   3223  C  C     . ASN A 1 416 ? 408.637 388.933 322.428 1.00 123.25 ? 416 ASN B C     1 
ATOM   3224  O  O     . ASN A 1 416 ? 408.092 389.737 321.661 1.00 123.02 ? 416 ASN B O     1 
ATOM   3225  C  CB    . ASN A 1 416 ? 409.402 389.624 324.717 1.00 125.78 ? 416 ASN B CB    1 
ATOM   3226  C  CG    . ASN A 1 416 ? 408.952 389.986 326.121 1.00 131.68 ? 416 ASN B CG    1 
ATOM   3227  O  OD1   . ASN A 1 416 ? 407.867 390.537 326.313 1.00 128.95 ? 416 ASN B OD1   1 
ATOM   3228  N  ND2   . ASN A 1 416 ? 409.784 389.680 327.108 1.00 133.05 ? 416 ASN B ND2   1 
ATOM   3229  N  N     . ASP A 1 417 ? 409.502 388.011 322.001 1.00 118.88 ? 417 ASP B N     1 
ATOM   3230  C  CA    . ASP A 1 417 ? 409.807 387.876 320.581 1.00 118.20 ? 417 ASP B CA    1 
ATOM   3231  C  C     . ASP A 1 417 ? 408.569 387.480 319.784 1.00 116.08 ? 417 ASP B C     1 
ATOM   3232  O  O     . ASP A 1 417 ? 408.356 387.975 318.673 1.00 116.38 ? 417 ASP B O     1 
ATOM   3233  C  CB    . ASP A 1 417 ? 410.917 386.846 320.381 1.00 120.16 ? 417 ASP B CB    1 
ATOM   3234  C  CG    . ASP A 1 417 ? 412.210 387.243 321.060 1.00 121.40 ? 417 ASP B CG    1 
ATOM   3235  O  OD1   . ASP A 1 417 ? 412.325 388.410 321.489 1.00 116.75 ? 417 ASP B OD1   1 
ATOM   3236  O  OD2   . ASP A 1 417 ? 413.112 386.387 321.167 1.00 123.07 ? 417 ASP B OD2   1 
ATOM   3237  N  N     . LEU A 1 418 ? 407.742 386.589 320.336 1.00 106.13 ? 418 LEU B N     1 
ATOM   3238  C  CA    . LEU A 1 418 ? 406.556 386.130 319.618 1.00 107.90 ? 418 LEU B CA    1 
ATOM   3239  C  C     . LEU A 1 418 ? 405.556 387.263 319.415 1.00 106.97 ? 418 LEU B C     1 
ATOM   3240  O  O     . LEU A 1 418 ? 405.024 387.444 318.313 1.00 107.25 ? 418 LEU B O     1 
ATOM   3241  C  CB    . LEU A 1 418 ? 405.909 384.968 320.375 1.00 109.40 ? 418 LEU B CB    1 
ATOM   3242  C  CG    . LEU A 1 418 ? 404.660 384.313 319.775 1.00 104.41 ? 418 LEU B CG    1 
ATOM   3243  C  CD1   . LEU A 1 418 ? 404.942 383.738 318.396 1.00 105.49 ? 418 LEU B CD1   1 
ATOM   3244  C  CD2   . LEU A 1 418 ? 404.145 383.233 320.707 1.00 102.76 ? 418 LEU B CD2   1 
ATOM   3245  N  N     . VAL A 1 419 ? 405.275 388.028 320.472 1.00 108.15 ? 419 VAL B N     1 
ATOM   3246  C  CA    . VAL A 1 419 ? 404.335 389.138 320.325 1.00 105.03 ? 419 VAL B CA    1 
ATOM   3247  C  C     . VAL A 1 419 ? 404.923 390.223 319.431 1.00 111.81 ? 419 VAL B C     1 
ATOM   3248  O  O     . VAL A 1 419 ? 404.187 390.884 318.687 1.00 111.66 ? 419 VAL B O     1 
ATOM   3249  C  CB    . VAL A 1 419 ? 403.895 389.706 321.692 1.00 106.56 ? 419 VAL B CB    1 
ATOM   3250  C  CG1   . VAL A 1 419 ? 403.174 388.639 322.502 1.00 110.03 ? 419 VAL B CG1   1 
ATOM   3251  C  CG2   . VAL A 1 419 ? 405.060 390.292 322.482 1.00 104.79 ? 419 VAL B CG2   1 
ATOM   3252  N  N     . SER A 1 420 ? 406.245 390.429 319.480 1.00 109.97 ? 420 SER B N     1 
ATOM   3253  C  CA    . SER A 1 420 ? 406.874 391.374 318.563 1.00 107.54 ? 420 SER B CA    1 
ATOM   3254  C  C     . SER A 1 420 ? 406.696 390.931 317.116 1.00 104.36 ? 420 SER B C     1 
ATOM   3255  O  O     . SER A 1 420 ? 406.398 391.752 316.239 1.00 102.40 ? 420 SER B O     1 
ATOM   3256  C  CB    . SER A 1 420 ? 408.358 391.516 318.905 1.00 105.64 ? 420 SER B CB    1 
ATOM   3257  O  OG    . SER A 1 420 ? 408.950 392.613 318.228 1.00 108.30 ? 420 SER B OG    1 
ATOM   3258  N  N     . GLU A 1 421 ? 406.868 389.634 316.850 1.00 113.25 ? 421 GLU B N     1 
ATOM   3259  C  CA    . GLU A 1 421 ? 406.654 389.113 315.504 1.00 115.84 ? 421 GLU B CA    1 
ATOM   3260  C  C     . GLU A 1 421 ? 405.206 389.286 315.068 1.00 115.20 ? 421 GLU B C     1 
ATOM   3261  O  O     . GLU A 1 421 ? 404.938 389.655 313.920 1.00 121.51 ? 421 GLU B O     1 
ATOM   3262  C  CB    . GLU A 1 421 ? 407.056 387.641 315.443 1.00 117.42 ? 421 GLU B CB    1 
ATOM   3263  C  CG    . GLU A 1 421 ? 408.555 387.408 315.407 1.00 119.93 ? 421 GLU B CG    1 
ATOM   3264  C  CD    . GLU A 1 421 ? 408.911 385.939 315.309 1.00 121.89 ? 421 GLU B CD    1 
ATOM   3265  O  OE1   . GLU A 1 421 ? 408.878 385.390 314.188 1.00 122.23 ? 421 GLU B OE1   1 
ATOM   3266  O  OE2   . GLU A 1 421 ? 409.224 385.334 316.355 1.00 121.76 ? 421 GLU B OE2   1 
ATOM   3267  N  N     . TYR A 1 422 ? 404.258 389.023 315.971 1.00 100.72 ? 422 TYR B N     1 
ATOM   3268  C  CA    . TYR A 1 422 ? 402.848 389.195 315.623 1.00 100.76 ? 422 TYR B CA    1 
ATOM   3269  C  C     . TYR A 1 422 ? 402.513 390.650 315.322 1.00 102.56 ? 422 TYR B C     1 
ATOM   3270  O  O     . TYR A 1 422 ? 401.734 390.925 314.403 1.00 102.22 ? 422 TYR B O     1 
ATOM   3271  C  CB    . TYR A 1 422 ? 401.938 388.682 316.745 1.00 103.31 ? 422 TYR B CB    1 
ATOM   3272  C  CG    . TYR A 1 422 ? 401.367 387.298 316.517 1.00 100.30 ? 422 TYR B CG    1 
ATOM   3273  C  CD1   . TYR A 1 422 ? 400.454 387.057 315.497 1.00 99.95  ? 422 TYR B CD1   1 
ATOM   3274  C  CD2   . TYR A 1 422 ? 401.735 386.234 317.327 1.00 103.61 ? 422 TYR B CD2   1 
ATOM   3275  C  CE1   . TYR A 1 422 ? 399.932 385.799 315.289 1.00 105.32 ? 422 TYR B CE1   1 
ATOM   3276  C  CE2   . TYR A 1 422 ? 401.215 384.971 317.127 1.00 102.18 ? 422 TYR B CE2   1 
ATOM   3277  C  CZ    . TYR A 1 422 ? 400.317 384.760 316.105 1.00 106.68 ? 422 TYR B CZ    1 
ATOM   3278  O  OH    . TYR A 1 422 ? 399.796 383.504 315.900 1.00 110.02 ? 422 TYR B OH    1 
ATOM   3279  N  N     . GLN A 1 423 ? 403.086 391.590 316.074 1.00 115.46 ? 423 GLN B N     1 
ATOM   3280  C  CA    . GLN A 1 423 ? 402.823 393.004 315.837 1.00 118.37 ? 423 GLN B CA    1 
ATOM   3281  C  C     . GLN A 1 423 ? 403.559 393.547 314.617 1.00 116.12 ? 423 GLN B C     1 
ATOM   3282  O  O     . GLN A 1 423 ? 403.119 394.555 314.049 1.00 111.79 ? 423 GLN B O     1 
ATOM   3283  C  CB    . GLN A 1 423 ? 403.204 393.813 317.084 1.00 119.55 ? 423 GLN B CB    1 
ATOM   3284  C  CG    . GLN A 1 423 ? 402.932 395.324 317.018 1.00 120.78 ? 423 GLN B CG    1 
ATOM   3285  C  CD    . GLN A 1 423 ? 401.473 395.657 316.775 1.00 119.12 ? 423 GLN B CD    1 
ATOM   3286  O  OE1   . GLN A 1 423 ? 400.585 394.857 317.066 1.00 120.56 ? 423 GLN B OE1   1 
ATOM   3287  N  NE2   . GLN A 1 423 ? 401.220 396.842 316.232 1.00 117.22 ? 423 GLN B NE2   1 
ATOM   3288  N  N     . GLN A 1 424 ? 404.666 392.912 314.212 1.00 111.56 ? 424 GLN B N     1 
ATOM   3289  C  CA    . GLN A 1 424 ? 405.448 393.420 313.085 1.00 106.25 ? 424 GLN B CA    1 
ATOM   3290  C  C     . GLN A 1 424 ? 404.630 393.419 311.798 1.00 98.12  ? 424 GLN B C     1 
ATOM   3291  O  O     . GLN A 1 424 ? 404.680 394.382 311.026 1.00 103.60 ? 424 GLN B O     1 
ATOM   3292  C  CB    . GLN A 1 424 ? 406.746 392.602 312.937 1.00 108.90 ? 424 GLN B CB    1 
ATOM   3293  C  CG    . GLN A 1 424 ? 407.317 392.384 311.519 1.00 107.24 ? 424 GLN B CG    1 
ATOM   3294  C  CD    . GLN A 1 424 ? 408.563 391.524 311.537 1.00 114.20 ? 424 GLN B CD    1 
ATOM   3295  O  OE1   . GLN A 1 424 ? 409.253 391.431 312.551 1.00 110.22 ? 424 GLN B OE1   1 
ATOM   3296  N  NE2   . GLN A 1 424 ? 408.858 390.885 310.410 1.00 114.67 ? 424 GLN B NE2   1 
ATOM   3297  N  N     . TYR A 1 425 ? 403.870 392.353 311.552 1.00 93.00  ? 425 TYR B N     1 
ATOM   3298  C  CA    . TYR A 1 425 ? 403.097 392.265 310.317 1.00 102.35 ? 425 TYR B CA    1 
ATOM   3299  C  C     . TYR A 1 425 ? 401.829 393.105 310.372 1.00 105.03 ? 425 TYR B C     1 
ATOM   3300  O  O     . TYR A 1 425 ? 401.341 393.545 309.325 1.00 106.12 ? 425 TYR B O     1 
ATOM   3301  C  CB    . TYR A 1 425 ? 402.779 390.804 310.014 1.00 99.83  ? 425 TYR B CB    1 
ATOM   3302  C  CG    . TYR A 1 425 ? 404.025 389.956 310.002 1.00 105.29 ? 425 TYR B CG    1 
ATOM   3303  C  CD1   . TYR A 1 425 ? 404.968 390.092 308.994 1.00 107.64 ? 425 TYR B CD1   1 
ATOM   3304  C  CD2   . TYR A 1 425 ? 404.277 389.048 311.014 1.00 105.52 ? 425 TYR B CD2   1 
ATOM   3305  C  CE1   . TYR A 1 425 ? 406.117 389.331 308.985 1.00 105.13 ? 425 TYR B CE1   1 
ATOM   3306  C  CE2   . TYR A 1 425 ? 405.425 388.285 311.016 1.00 110.47 ? 425 TYR B CE2   1 
ATOM   3307  C  CZ    . TYR A 1 425 ? 406.344 388.433 310.003 1.00 110.89 ? 425 TYR B CZ    1 
ATOM   3308  O  OH    . TYR A 1 425 ? 407.483 387.663 310.002 1.00 109.02 ? 425 TYR B OH    1 
ATOM   3309  N  N     . GLN A 1 426 ? 401.279 393.339 311.565 1.00 109.76 ? 426 GLN B N     1 
ATOM   3310  C  CA    . GLN A 1 426 ? 400.217 394.331 311.688 1.00 113.43 ? 426 GLN B CA    1 
ATOM   3311  C  C     . GLN A 1 426 ? 400.739 395.720 311.346 1.00 119.23 ? 426 GLN B C     1 
ATOM   3312  O  O     . GLN A 1 426 ? 400.057 396.502 310.674 1.00 109.94 ? 426 GLN B O     1 
ATOM   3313  C  CB    . GLN A 1 426 ? 399.630 394.307 313.100 1.00 119.02 ? 426 GLN B CB    1 
ATOM   3314  C  CG    . GLN A 1 426 ? 398.509 395.324 313.324 1.00 119.99 ? 426 GLN B CG    1 
ATOM   3315  C  CD    . GLN A 1 426 ? 397.693 395.055 314.577 1.00 114.01 ? 426 GLN B CD    1 
ATOM   3316  O  OE1   . GLN A 1 426 ? 397.506 393.908 314.982 1.00 106.35 ? 426 GLN B OE1   1 
ATOM   3317  N  NE2   . GLN A 1 426 ? 397.206 396.121 315.202 1.00 112.90 ? 426 GLN B NE2   1 
ATOM   3318  N  N     . ASP A 1 427 ? 401.950 396.045 311.801 1.00 133.94 ? 427 ASP B N     1 
ATOM   3319  C  CA    . ASP A 1 427 ? 402.566 397.324 311.473 1.00 133.01 ? 427 ASP B CA    1 
ATOM   3320  C  C     . ASP A 1 427 ? 403.080 397.395 310.039 1.00 131.87 ? 427 ASP B C     1 
ATOM   3321  O  O     . ASP A 1 427 ? 403.311 398.502 309.540 1.00 130.61 ? 427 ASP B O     1 
ATOM   3322  C  CB    . ASP A 1 427 ? 403.721 397.607 312.438 1.00 129.10 ? 427 ASP B CB    1 
ATOM   3323  N  N     . ALA A 1 428 ? 403.266 396.260 309.371 1.00 122.79 ? 428 ALA B N     1 
ATOM   3324  C  CA    . ALA A 1 428 ? 403.842 396.257 308.035 1.00 121.09 ? 428 ALA B CA    1 
ATOM   3325  C  C     . ALA A 1 428 ? 402.884 396.873 307.022 1.00 121.67 ? 428 ALA B C     1 
ATOM   3326  O  O     . ALA A 1 428 ? 401.661 396.819 307.173 1.00 119.38 ? 428 ALA B O     1 
ATOM   3327  C  CB    . ALA A 1 428 ? 404.195 394.832 307.613 1.00 116.17 ? 428 ALA B CB    1 
ATOM   3328  N  N     . THR A 1 429 ? 403.461 397.467 305.981 1.00 120.95 ? 429 THR B N     1 
ATOM   3329  C  CA    . THR A 1 429 ? 402.689 398.080 304.907 1.00 116.17 ? 429 THR B CA    1 
ATOM   3330  C  C     . THR A 1 429 ? 403.478 398.050 303.603 1.00 111.93 ? 429 THR B C     1 
ATOM   3331  O  O     . THR A 1 429 ? 404.651 397.676 303.584 1.00 110.10 ? 429 THR B O     1 
ATOM   3332  C  CB    . THR A 1 429 ? 402.315 399.536 305.238 1.00 113.36 ? 429 THR B CB    1 
ATOM   3333  N  N     . MET B 1 1   ? 394.960 354.872 224.942 1.00 134.37 ? 1   MET E N     1 
ATOM   3334  C  CA    . MET B 1 1   ? 395.372 355.984 224.039 1.00 132.65 ? 1   MET E CA    1 
ATOM   3335  C  C     . MET B 1 1   ? 395.183 357.331 224.726 1.00 133.61 ? 1   MET E C     1 
ATOM   3336  O  O     . MET B 1 1   ? 394.069 357.683 225.114 1.00 135.07 ? 1   MET E O     1 
ATOM   3337  C  CB    . MET B 1 1   ? 394.571 355.941 222.738 1.00 129.19 ? 1   MET E CB    1 
ATOM   3338  N  N     . ARG B 1 2   ? 396.284 358.070 224.876 1.00 119.77 ? 2   ARG E N     1 
ATOM   3339  C  CA    . ARG B 1 2   ? 396.285 359.405 225.477 1.00 115.87 ? 2   ARG E CA    1 
ATOM   3340  C  C     . ARG B 1 2   ? 395.763 359.367 226.916 1.00 120.41 ? 2   ARG E C     1 
ATOM   3341  O  O     . ARG B 1 2   ? 394.735 359.957 227.251 1.00 125.66 ? 2   ARG E O     1 
ATOM   3342  C  CB    . ARG B 1 2   ? 395.469 360.382 224.626 1.00 116.50 ? 2   ARG E CB    1 
ATOM   3343  C  CG    . ARG B 1 2   ? 395.963 360.530 223.199 1.00 115.43 ? 2   ARG E CG    1 
ATOM   3344  C  CD    . ARG B 1 2   ? 395.227 361.646 222.478 1.00 113.78 ? 2   ARG E CD    1 
ATOM   3345  N  NE    . ARG B 1 2   ? 393.795 361.384 222.386 1.00 117.41 ? 2   ARG E NE    1 
ATOM   3346  C  CZ    . ARG B 1 2   ? 392.914 362.146 221.749 1.00 120.40 ? 2   ARG E CZ    1 
ATOM   3347  N  NH1   . ARG B 1 2   ? 393.274 363.249 221.106 1.00 122.30 ? 2   ARG E NH1   1 
ATOM   3348  N  NH2   . ARG B 1 2   ? 391.631 361.797 221.762 1.00 121.04 ? 2   ARG E NH2   1 
ATOM   3349  N  N     . GLU B 1 3   ? 396.500 358.661 227.767 1.00 126.87 ? 3   GLU E N     1 
ATOM   3350  C  CA    . GLU B 1 3   ? 396.086 358.462 229.146 1.00 124.86 ? 3   GLU E CA    1 
ATOM   3351  C  C     . GLU B 1 3   ? 396.456 359.666 230.009 1.00 121.29 ? 3   GLU E C     1 
ATOM   3352  O  O     . GLU B 1 3   ? 397.317 360.476 229.659 1.00 122.91 ? 3   GLU E O     1 
ATOM   3353  C  CB    . GLU B 1 3   ? 396.733 357.200 229.716 1.00 126.38 ? 3   GLU E CB    1 
ATOM   3354  C  CG    . GLU B 1 3   ? 396.162 355.899 229.167 1.00 130.48 ? 3   GLU E CG    1 
ATOM   3355  C  CD    . GLU B 1 3   ? 396.879 355.429 227.917 1.00 134.66 ? 3   GLU E CD    1 
ATOM   3356  O  OE1   . GLU B 1 3   ? 396.842 356.150 226.902 1.00 134.83 ? 3   GLU E OE1   1 
ATOM   3357  O  OE2   . GLU B 1 3   ? 397.479 354.335 227.950 1.00 136.23 ? 3   GLU E OE2   1 
ATOM   3358  N  N     . ILE B 1 4   ? 395.775 359.775 231.152 1.00 100.65 ? 4   ILE E N     1 
ATOM   3359  C  CA    . ILE B 1 4   ? 396.064 360.769 232.181 1.00 96.50  ? 4   ILE E CA    1 
ATOM   3360  C  C     . ILE B 1 4   ? 396.141 360.042 233.514 1.00 98.37  ? 4   ILE E C     1 
ATOM   3361  O  O     . ILE B 1 4   ? 395.276 359.214 233.822 1.00 95.26  ? 4   ILE E O     1 
ATOM   3362  C  CB    . ILE B 1 4   ? 394.993 361.878 232.244 1.00 94.23  ? 4   ILE E CB    1 
ATOM   3363  C  CG1   . ILE B 1 4   ? 395.068 362.782 231.014 1.00 101.82 ? 4   ILE E CG1   1 
ATOM   3364  C  CG2   . ILE B 1 4   ? 395.166 362.736 233.506 1.00 97.91  ? 4   ILE E CG2   1 
ATOM   3365  C  CD1   . ILE B 1 4   ? 393.754 363.456 230.686 1.00 106.69 ? 4   ILE E CD1   1 
ATOM   3366  N  N     . VAL B 1 5   ? 397.163 360.361 234.303 1.00 109.96 ? 5   VAL E N     1 
ATOM   3367  C  CA    . VAL B 1 5   ? 397.325 359.841 235.656 1.00 108.49 ? 5   VAL E CA    1 
ATOM   3368  C  C     . VAL B 1 5   ? 396.840 360.925 236.610 1.00 110.08 ? 5   VAL E C     1 
ATOM   3369  O  O     . VAL B 1 5   ? 397.314 362.067 236.558 1.00 114.31 ? 5   VAL E O     1 
ATOM   3370  C  CB    . VAL B 1 5   ? 398.786 359.446 235.931 1.00 112.12 ? 5   VAL E CB    1 
ATOM   3371  C  CG1   . VAL B 1 5   ? 399.103 359.397 237.435 1.00 113.05 ? 5   VAL E CG1   1 
ATOM   3372  C  CG2   . VAL B 1 5   ? 399.095 358.108 235.280 1.00 114.45 ? 5   VAL E CG2   1 
ATOM   3373  N  N     . HIS B 1 6   ? 395.894 360.567 237.475 1.00 98.12  ? 6   HIS E N     1 
ATOM   3374  C  CA    . HIS B 1 6   ? 395.273 361.494 238.409 1.00 94.52  ? 6   HIS E CA    1 
ATOM   3375  C  C     . HIS B 1 6   ? 395.828 361.271 239.808 1.00 87.66  ? 6   HIS E C     1 
ATOM   3376  O  O     . HIS B 1 6   ? 395.957 360.130 240.258 1.00 96.16  ? 6   HIS E O     1 
ATOM   3377  C  CB    . HIS B 1 6   ? 393.755 361.319 238.425 1.00 99.25  ? 6   HIS E CB    1 
ATOM   3378  C  CG    . HIS B 1 6   ? 393.073 362.082 239.517 1.00 100.35 ? 6   HIS E CG    1 
ATOM   3379  N  ND1   . HIS B 1 6   ? 392.735 363.415 239.396 1.00 98.30  ? 6   HIS E ND1   1 
ATOM   3380  C  CD2   . HIS B 1 6   ? 392.666 361.701 240.750 1.00 97.49  ? 6   HIS E CD2   1 
ATOM   3381  C  CE1   . HIS B 1 6   ? 392.148 363.820 240.507 1.00 99.61  ? 6   HIS E CE1   1 
ATOM   3382  N  NE2   . HIS B 1 6   ? 392.097 362.800 241.345 1.00 94.86  ? 6   HIS E NE2   1 
ATOM   3383  N  N     . ILE B 1 7   ? 396.156 362.371 240.486 1.00 86.70  ? 7   ILE E N     1 
ATOM   3384  C  CA    . ILE B 1 7   ? 396.612 362.369 241.871 1.00 91.39  ? 7   ILE E CA    1 
ATOM   3385  C  C     . ILE B 1 7   ? 395.740 363.344 242.653 1.00 94.89  ? 7   ILE E C     1 
ATOM   3386  O  O     . ILE B 1 7   ? 395.304 364.374 242.129 1.00 101.46 ? 7   ILE E O     1 
ATOM   3387  C  CB    . ILE B 1 7   ? 398.113 362.738 241.991 1.00 87.23  ? 7   ILE E CB    1 
ATOM   3388  C  CG1   . ILE B 1 7   ? 398.966 361.833 241.090 1.00 90.20  ? 7   ILE E CG1   1 
ATOM   3389  C  CG2   . ILE B 1 7   ? 398.600 362.633 243.448 1.00 91.74  ? 7   ILE E CG2   1 
ATOM   3390  C  CD1   . ILE B 1 7   ? 399.473 362.516 239.842 1.00 94.49  ? 7   ILE E CD1   1 
ATOM   3391  N  N     . GLN B 1 8   ? 395.475 363.006 243.916 1.00 93.99  ? 8   GLN E N     1 
ATOM   3392  C  CA    . GLN B 1 8   ? 394.682 363.857 244.800 1.00 94.82  ? 8   GLN E CA    1 
ATOM   3393  C  C     . GLN B 1 8   ? 395.322 363.884 246.178 1.00 98.15  ? 8   GLN E C     1 
ATOM   3394  O  O     . GLN B 1 8   ? 395.340 362.865 246.875 1.00 108.38 ? 8   GLN E O     1 
ATOM   3395  C  CB    . GLN B 1 8   ? 393.219 363.388 244.872 1.00 101.66 ? 8   GLN E CB    1 
ATOM   3396  C  CG    . GLN B 1 8   ? 392.977 361.941 245.291 1.00 99.66  ? 8   GLN E CG    1 
ATOM   3397  C  CD    . GLN B 1 8   ? 391.574 361.469 244.950 1.00 101.75 ? 8   GLN E CD    1 
ATOM   3398  O  OE1   . GLN B 1 8   ? 390.650 361.597 245.751 1.00 108.67 ? 8   GLN E OE1   1 
ATOM   3399  N  NE2   . GLN B 1 8   ? 391.409 360.922 243.756 1.00 97.46  ? 8   GLN E NE2   1 
ATOM   3400  N  N     . ALA B 1 9   ? 395.825 365.059 246.567 1.00 90.46  ? 9   ALA E N     1 
ATOM   3401  C  CA    . ALA B 1 9   ? 396.566 365.264 247.804 1.00 85.71  ? 9   ALA E CA    1 
ATOM   3402  C  C     . ALA B 1 9   ? 395.810 366.232 248.701 1.00 92.73  ? 9   ALA E C     1 
ATOM   3403  O  O     . ALA B 1 9   ? 395.193 367.186 248.218 1.00 103.96 ? 9   ALA E O     1 
ATOM   3404  C  CB    . ALA B 1 9   ? 397.967 365.810 247.524 1.00 91.11  ? 9   ALA E CB    1 
ATOM   3405  N  N     . GLY B 1 10  ? 395.860 365.984 250.006 1.00 100.27 ? 10  GLY E N     1 
ATOM   3406  C  CA    . GLY B 1 10  ? 395.154 366.803 250.967 1.00 104.14 ? 10  GLY E CA    1 
ATOM   3407  C  C     . GLY B 1 10  ? 393.685 366.434 251.055 1.00 106.95 ? 10  GLY E C     1 
ATOM   3408  O  O     . GLY B 1 10  ? 393.138 365.705 250.229 1.00 109.30 ? 10  GLY E O     1 
ATOM   3409  N  N     . GLN B 1 11  ? 393.032 366.961 252.094 1.00 114.31 ? 11  GLN E N     1 
ATOM   3410  C  CA    . GLN B 1 11  ? 391.597 366.746 252.258 1.00 114.25 ? 11  GLN E CA    1 
ATOM   3411  C  C     . GLN B 1 11  ? 390.821 367.362 251.103 1.00 117.40 ? 11  GLN E C     1 
ATOM   3412  O  O     . GLN B 1 11  ? 389.901 366.742 250.551 1.00 121.08 ? 11  GLN E O     1 
ATOM   3413  C  CB    . GLN B 1 11  ? 391.132 367.339 253.589 1.00 115.50 ? 11  GLN E CB    1 
ATOM   3414  C  CG    . GLN B 1 11  ? 389.646 367.166 253.880 1.00 121.54 ? 11  GLN E CG    1 
ATOM   3415  C  CD    . GLN B 1 11  ? 389.294 367.529 255.307 1.00 125.64 ? 11  GLN E CD    1 
ATOM   3416  O  OE1   . GLN B 1 11  ? 390.093 368.140 256.016 1.00 118.92 ? 11  GLN E OE1   1 
ATOM   3417  N  NE2   . GLN B 1 11  ? 388.091 367.164 255.734 1.00 126.59 ? 11  GLN E NE2   1 
ATOM   3418  N  N     . CYS B 1 12  ? 391.183 368.591 250.731 1.00 112.10 ? 12  CYS E N     1 
ATOM   3419  C  CA    . CYS B 1 12  ? 390.512 369.291 249.641 1.00 112.27 ? 12  CYS E CA    1 
ATOM   3420  C  C     . CYS B 1 12  ? 390.661 368.534 248.331 1.00 111.69 ? 12  CYS E C     1 
ATOM   3421  O  O     . CYS B 1 12  ? 389.673 368.282 247.624 1.00 115.79 ? 12  CYS E O     1 
ATOM   3422  C  CB    . CYS B 1 12  ? 391.096 370.694 249.511 1.00 112.73 ? 12  CYS E CB    1 
ATOM   3423  S  SG    . CYS B 1 12  ? 390.727 371.509 247.961 1.00 124.22 ? 12  CYS E SG    1 
ATOM   3424  N  N     . GLY B 1 13  ? 391.897 368.161 247.998 1.00 108.77 ? 13  GLY E N     1 
ATOM   3425  C  CA    . GLY B 1 13  ? 392.135 367.419 246.776 1.00 109.61 ? 13  GLY E CA    1 
ATOM   3426  C  C     . GLY B 1 13  ? 391.439 366.075 246.773 1.00 104.56 ? 13  GLY E C     1 
ATOM   3427  O  O     . GLY B 1 13  ? 390.889 365.660 245.755 1.00 112.02 ? 13  GLY E O     1 
ATOM   3428  N  N     . ASN B 1 14  ? 391.442 365.383 247.916 1.00 101.71 ? 14  ASN E N     1 
ATOM   3429  C  CA    . ASN B 1 14  ? 390.807 364.071 247.982 1.00 104.93 ? 14  ASN E CA    1 
ATOM   3430  C  C     . ASN B 1 14  ? 389.301 364.168 247.782 1.00 106.34 ? 14  ASN E C     1 
ATOM   3431  O  O     . ASN B 1 14  ? 388.719 363.372 247.036 1.00 109.41 ? 14  ASN E O     1 
ATOM   3432  C  CB    . ASN B 1 14  ? 391.123 363.395 249.314 1.00 105.33 ? 14  ASN E CB    1 
ATOM   3433  C  CG    . ASN B 1 14  ? 392.395 362.580 249.260 1.00 108.56 ? 14  ASN E CG    1 
ATOM   3434  O  OD1   . ASN B 1 14  ? 392.358 361.364 249.082 1.00 108.93 ? 14  ASN E OD1   1 
ATOM   3435  N  ND2   . ASN B 1 14  ? 393.530 363.246 249.412 1.00 112.67 ? 14  ASN E ND2   1 
ATOM   3436  N  N     . GLN B 1 15  ? 388.651 365.138 248.427 1.00 101.90 ? 15  GLN E N     1 
ATOM   3437  C  CA    . GLN B 1 15  ? 387.205 365.269 248.271 1.00 98.41  ? 15  GLN E CA    1 
ATOM   3438  C  C     . GLN B 1 15  ? 386.836 365.697 246.855 1.00 98.19  ? 15  GLN E C     1 
ATOM   3439  O  O     . GLN B 1 15  ? 385.870 365.177 246.272 1.00 102.43 ? 15  GLN E O     1 
ATOM   3440  C  CB    . GLN B 1 15  ? 386.660 366.253 249.303 1.00 100.76 ? 15  GLN E CB    1 
ATOM   3441  C  CG    . GLN B 1 15  ? 386.674 365.699 250.718 1.00 102.00 ? 15  GLN E CG    1 
ATOM   3442  C  CD    . GLN B 1 15  ? 386.091 366.659 251.733 1.00 109.59 ? 15  GLN E CD    1 
ATOM   3443  O  OE1   . GLN B 1 15  ? 386.347 367.861 251.686 1.00 109.29 ? 15  GLN E OE1   1 
ATOM   3444  N  NE2   . GLN B 1 15  ? 385.303 366.131 252.663 1.00 109.54 ? 15  GLN E NE2   1 
ATOM   3445  N  N     . ILE B 1 16  ? 387.598 366.630 246.275 1.00 78.45  ? 16  ILE E N     1 
ATOM   3446  C  CA    . ILE B 1 16  ? 387.309 367.050 244.907 1.00 72.88  ? 16  ILE E CA    1 
ATOM   3447  C  C     . ILE B 1 16  ? 387.555 365.903 243.937 1.00 87.30  ? 16  ILE E C     1 
ATOM   3448  O  O     . ILE B 1 16  ? 386.809 365.729 242.970 1.00 91.50  ? 16  ILE E O     1 
ATOM   3449  C  CB    . ILE B 1 16  ? 388.125 368.305 244.537 1.00 76.44  ? 16  ILE E CB    1 
ATOM   3450  C  CG1   . ILE B 1 16  ? 387.563 369.531 245.259 1.00 83.45  ? 16  ILE E CG1   1 
ATOM   3451  C  CG2   . ILE B 1 16  ? 388.121 368.551 243.027 1.00 87.15  ? 16  ILE E CG2   1 
ATOM   3452  C  CD1   . ILE B 1 16  ? 388.537 370.678 245.384 1.00 84.74  ? 16  ILE E CD1   1 
ATOM   3453  N  N     . GLY B 1 17  ? 388.600 365.108 244.168 1.00 98.48  ? 17  GLY E N     1 
ATOM   3454  C  CA    . GLY B 1 17  ? 388.842 363.965 243.308 1.00 100.57 ? 17  GLY E CA    1 
ATOM   3455  C  C     . GLY B 1 17  ? 387.752 362.919 243.426 1.00 102.56 ? 17  GLY E C     1 
ATOM   3456  O  O     . GLY B 1 17  ? 387.378 362.287 242.434 1.00 99.77  ? 17  GLY E O     1 
ATOM   3457  N  N     . ALA B 1 18  ? 387.224 362.729 244.638 1.00 100.25 ? 18  ALA E N     1 
ATOM   3458  C  CA    . ALA B 1 18  ? 386.113 361.804 244.825 1.00 101.64 ? 18  ALA E CA    1 
ATOM   3459  C  C     . ALA B 1 18  ? 384.897 362.249 244.024 1.00 102.56 ? 18  ALA E C     1 
ATOM   3460  O  O     . ALA B 1 18  ? 384.303 361.454 243.284 1.00 103.85 ? 18  ALA E O     1 
ATOM   3461  C  CB    . ALA B 1 18  ? 385.769 361.694 246.311 1.00 99.43  ? 18  ALA E CB    1 
ATOM   3462  N  N     . LYS B 1 19  ? 384.531 363.530 244.133 1.00 102.45 ? 19  LYS E N     1 
ATOM   3463  C  CA    . LYS B 1 19  ? 383.383 364.019 243.369 1.00 101.01 ? 19  LYS E CA    1 
ATOM   3464  C  C     . LYS B 1 19  ? 383.660 364.011 241.871 1.00 102.69 ? 19  LYS E C     1 
ATOM   3465  O  O     . LYS B 1 19  ? 382.747 363.764 241.072 1.00 107.17 ? 19  LYS E O     1 
ATOM   3466  C  CB    . LYS B 1 19  ? 382.985 365.413 243.848 1.00 100.21 ? 19  LYS E CB    1 
ATOM   3467  C  CG    . LYS B 1 19  ? 382.103 365.450 245.119 1.00 102.77 ? 19  LYS E CG    1 
ATOM   3468  C  CD    . LYS B 1 19  ? 380.670 364.897 244.944 1.00 103.21 ? 19  LYS E CD    1 
ATOM   3469  C  CE    . LYS B 1 19  ? 379.808 364.938 246.203 1.00 104.77 ? 19  LYS E CE    1 
ATOM   3470  N  NZ    . LYS B 1 19  ? 379.503 366.307 246.690 1.00 107.00 ? 19  LYS E NZ    1 
ATOM   3471  N  N     . PHE B 1 20  ? 384.912 364.241 241.478 1.00 90.32  ? 20  PHE E N     1 
ATOM   3472  C  CA    . PHE B 1 20  ? 385.290 364.151 240.075 1.00 89.21  ? 20  PHE E CA    1 
ATOM   3473  C  C     . PHE B 1 20  ? 385.086 362.741 239.547 1.00 96.83  ? 20  PHE E C     1 
ATOM   3474  O  O     . PHE B 1 20  ? 384.583 362.553 238.433 1.00 101.28 ? 20  PHE E O     1 
ATOM   3475  C  CB    . PHE B 1 20  ? 386.742 364.604 239.921 1.00 93.81  ? 20  PHE E CB    1 
ATOM   3476  C  CG    . PHE B 1 20  ? 387.401 364.145 238.662 1.00 94.87  ? 20  PHE E CG    1 
ATOM   3477  C  CD1   . PHE B 1 20  ? 387.082 364.725 237.449 1.00 94.84  ? 20  PHE E CD1   1 
ATOM   3478  C  CD2   . PHE B 1 20  ? 388.363 363.152 238.694 1.00 94.54  ? 20  PHE E CD2   1 
ATOM   3479  C  CE1   . PHE B 1 20  ? 387.696 364.310 236.291 1.00 92.64  ? 20  PHE E CE1   1 
ATOM   3480  C  CE2   . PHE B 1 20  ? 388.979 362.735 237.540 1.00 94.42  ? 20  PHE E CE2   1 
ATOM   3481  C  CZ    . PHE B 1 20  ? 388.645 363.316 236.338 1.00 94.69  ? 20  PHE E CZ    1 
ATOM   3482  N  N     . TRP B 1 21  ? 385.439 361.733 240.346 1.00 85.93  ? 21  TRP E N     1 
ATOM   3483  C  CA    . TRP B 1 21  ? 385.255 360.362 239.893 1.00 89.33  ? 21  TRP E CA    1 
ATOM   3484  C  C     . TRP B 1 21  ? 383.786 359.954 239.912 1.00 86.99  ? 21  TRP E C     1 
ATOM   3485  O  O     . TRP B 1 21  ? 383.367 359.169 239.053 1.00 87.87  ? 21  TRP E O     1 
ATOM   3486  C  CB    . TRP B 1 21  ? 386.107 359.408 240.728 1.00 86.58  ? 21  TRP E CB    1 
ATOM   3487  C  CG    . TRP B 1 21  ? 387.555 359.441 240.332 1.00 77.91  ? 21  TRP E CG    1 
ATOM   3488  C  CD1   . TRP B 1 21  ? 388.604 359.836 241.103 1.00 81.40  ? 21  TRP E CD1   1 
ATOM   3489  C  CD2   . TRP B 1 21  ? 388.109 359.078 239.060 1.00 73.97  ? 21  TRP E CD2   1 
ATOM   3490  N  NE1   . TRP B 1 21  ? 389.776 359.741 240.397 1.00 85.83  ? 21  TRP E NE1   1 
ATOM   3491  C  CE2   . TRP B 1 21  ? 389.499 359.278 239.138 1.00 78.81  ? 21  TRP E CE2   1 
ATOM   3492  C  CE3   . TRP B 1 21  ? 387.564 358.604 237.863 1.00 84.19  ? 21  TRP E CE3   1 
ATOM   3493  C  CZ2   . TRP B 1 21  ? 390.351 359.019 238.069 1.00 83.23  ? 21  TRP E CZ2   1 
ATOM   3494  C  CZ3   . TRP B 1 21  ? 388.409 358.350 236.804 1.00 93.47  ? 21  TRP E CZ3   1 
ATOM   3495  C  CH2   . TRP B 1 21  ? 389.787 358.557 236.913 1.00 88.44  ? 21  TRP E CH2   1 
ATOM   3496  N  N     . GLU B 1 22  ? 382.986 360.481 240.851 1.00 99.71  ? 22  GLU E N     1 
ATOM   3497  C  CA    . GLU B 1 22  ? 381.535 360.314 240.746 1.00 95.98  ? 22  GLU E CA    1 
ATOM   3498  C  C     . GLU B 1 22  ? 381.001 360.860 239.428 1.00 97.26  ? 22  GLU E C     1 
ATOM   3499  O  O     . GLU B 1 22  ? 380.236 360.181 238.737 1.00 105.60 ? 22  GLU E O     1 
ATOM   3500  C  CB    . GLU B 1 22  ? 380.781 360.961 241.919 1.00 100.10 ? 22  GLU E CB    1 
ATOM   3501  C  CG    . GLU B 1 22  ? 380.739 360.152 243.217 1.00 107.11 ? 22  GLU E CG    1 
ATOM   3502  C  CD    . GLU B 1 22  ? 380.990 360.922 244.499 1.00 111.91 ? 22  GLU E CD    1 
ATOM   3503  O  OE1   . GLU B 1 22  ? 382.120 361.357 244.763 1.00 108.08 ? 22  GLU E OE1   1 
ATOM   3504  O  OE2   . GLU B 1 22  ? 380.021 361.098 245.263 1.00 114.98 ? 22  GLU E OE2   1 
ATOM   3505  N  N     . VAL B 1 23  ? 381.402 362.078 239.057 1.00 91.20  ? 23  VAL E N     1 
ATOM   3506  C  CA    . VAL B 1 23  ? 380.886 362.682 237.826 1.00 93.59  ? 23  VAL E CA    1 
ATOM   3507  C  C     . VAL B 1 23  ? 381.343 361.885 236.607 1.00 99.54  ? 23  VAL E C     1 
ATOM   3508  O  O     . VAL B 1 23  ? 380.561 361.641 235.677 1.00 102.96 ? 23  VAL E O     1 
ATOM   3509  C  CB    . VAL B 1 23  ? 381.305 364.163 237.733 1.00 92.81  ? 23  VAL E CB    1 
ATOM   3510  C  CG1   . VAL B 1 23  ? 380.988 364.737 236.345 1.00 95.51  ? 23  VAL E CG1   1 
ATOM   3511  C  CG2   . VAL B 1 23  ? 380.603 364.984 238.808 1.00 96.30  ? 23  VAL E CG2   1 
ATOM   3512  N  N     . ILE B 1 24  ? 382.608 361.458 236.596 1.00 89.64  ? 24  ILE E N     1 
ATOM   3513  C  CA    . ILE B 1 24  ? 383.146 360.742 235.442 1.00 90.35  ? 24  ILE E CA    1 
ATOM   3514  C  C     . ILE B 1 24  ? 382.458 359.390 235.287 1.00 94.71  ? 24  ILE E C     1 
ATOM   3515  O  O     . ILE B 1 24  ? 382.018 359.024 234.190 1.00 99.69  ? 24  ILE E O     1 
ATOM   3516  C  CB    . ILE B 1 24  ? 384.674 360.589 235.575 1.00 87.28  ? 24  ILE E CB    1 
ATOM   3517  C  CG1   . ILE B 1 24  ? 385.372 361.945 235.415 1.00 88.67  ? 24  ILE E CG1   1 
ATOM   3518  C  CG2   . ILE B 1 24  ? 385.234 359.596 234.550 1.00 92.59  ? 24  ILE E CG2   1 
ATOM   3519  C  CD1   . ILE B 1 24  ? 385.517 362.448 233.983 1.00 92.19  ? 24  ILE E CD1   1 
ATOM   3520  N  N     . SER B 1 25  ? 382.355 358.626 236.379 1.00 95.28  ? 25  SER E N     1 
ATOM   3521  C  CA    . SER B 1 25  ? 381.702 357.325 236.305 1.00 98.74  ? 25  SER E CA    1 
ATOM   3522  C  C     . SER B 1 25  ? 380.221 357.464 235.988 1.00 100.73 ? 25  SER E C     1 
ATOM   3523  O  O     . SER B 1 25  ? 379.643 356.581 235.346 1.00 103.45 ? 25  SER E O     1 
ATOM   3524  C  CB    . SER B 1 25  ? 381.892 356.565 237.616 1.00 101.86 ? 25  SER E CB    1 
ATOM   3525  O  OG    . SER B 1 25  ? 381.261 357.235 238.692 1.00 107.55 ? 25  SER E OG    1 
ATOM   3526  N  N     . ASP B 1 26  ? 379.590 358.555 236.428 1.00 108.91 ? 26  ASP E N     1 
ATOM   3527  C  CA    . ASP B 1 26  ? 378.189 358.773 236.099 1.00 109.37 ? 26  ASP E CA    1 
ATOM   3528  C  C     . ASP B 1 26  ? 378.011 359.017 234.607 1.00 103.91 ? 26  ASP E C     1 
ATOM   3529  O  O     . ASP B 1 26  ? 377.141 358.410 233.971 1.00 107.75 ? 26  ASP E O     1 
ATOM   3530  C  CB    . ASP B 1 26  ? 377.644 359.950 236.906 1.00 112.76 ? 26  ASP E CB    1 
ATOM   3531  C  CG    . ASP B 1 26  ? 376.221 360.302 236.532 1.00 114.09 ? 26  ASP E CG    1 
ATOM   3532  O  OD1   . ASP B 1 26  ? 375.449 359.380 236.191 1.00 113.42 ? 26  ASP E OD1   1 
ATOM   3533  O  OD2   . ASP B 1 26  ? 375.873 361.500 236.577 1.00 116.88 ? 26  ASP E OD2   1 
ATOM   3534  N  N     . GLU B 1 27  ? 378.832 359.895 234.025 1.00 99.14  ? 27  GLU E N     1 
ATOM   3535  C  CA    . GLU B 1 27  ? 378.660 360.207 232.609 1.00 108.01 ? 27  GLU E CA    1 
ATOM   3536  C  C     . GLU B 1 27  ? 379.179 359.099 231.698 1.00 108.62 ? 27  GLU E C     1 
ATOM   3537  O  O     . GLU B 1 27  ? 378.779 359.048 230.531 1.00 114.05 ? 27  GLU E O     1 
ATOM   3538  C  CB    . GLU B 1 27  ? 379.317 361.552 232.274 1.00 106.10 ? 27  GLU E CB    1 
ATOM   3539  C  CG    . GLU B 1 27  ? 380.833 361.581 232.150 1.00 103.63 ? 27  GLU E CG    1 
ATOM   3540  C  CD    . GLU B 1 27  ? 381.336 362.982 231.879 1.00 112.40 ? 27  GLU E CD    1 
ATOM   3541  O  OE1   . GLU B 1 27  ? 381.148 363.862 232.744 1.00 107.77 ? 27  GLU E OE1   1 
ATOM   3542  O  OE2   . GLU B 1 27  ? 381.909 363.207 230.794 1.00 118.38 ? 27  GLU E OE2   1 
ATOM   3543  N  N     . HIS B 1 28  ? 380.052 358.219 232.195 1.00 110.19 ? 28  HIS E N     1 
ATOM   3544  C  CA    . HIS B 1 28  ? 380.475 357.029 231.462 1.00 108.24 ? 28  HIS E CA    1 
ATOM   3545  C  C     . HIS B 1 28  ? 379.610 355.804 231.745 1.00 113.55 ? 28  HIS E C     1 
ATOM   3546  O  O     . HIS B 1 28  ? 379.840 354.753 231.138 1.00 115.77 ? 28  HIS E O     1 
ATOM   3547  C  CB    . HIS B 1 28  ? 381.937 356.708 231.780 1.00 110.97 ? 28  HIS E CB    1 
ATOM   3548  C  CG    . HIS B 1 28  ? 382.911 357.447 230.919 1.00 115.94 ? 28  HIS E CG    1 
ATOM   3549  N  ND1   . HIS B 1 28  ? 383.173 357.084 229.616 1.00 115.98 ? 28  HIS E ND1   1 
ATOM   3550  C  CD2   . HIS B 1 28  ? 383.671 358.539 231.166 1.00 117.23 ? 28  HIS E CD2   1 
ATOM   3551  C  CE1   . HIS B 1 28  ? 384.064 357.913 229.102 1.00 113.72 ? 28  HIS E CE1   1 
ATOM   3552  N  NE2   . HIS B 1 28  ? 384.381 358.806 230.021 1.00 113.06 ? 28  HIS E NE2   1 
ATOM   3553  N  N     . GLY B 1 29  ? 378.620 355.906 232.625 1.00 119.17 ? 29  GLY E N     1 
ATOM   3554  C  CA    . GLY B 1 29  ? 377.739 354.782 232.888 1.00 119.13 ? 29  GLY E CA    1 
ATOM   3555  C  C     . GLY B 1 29  ? 378.406 353.613 233.579 1.00 120.07 ? 29  GLY E C     1 
ATOM   3556  O  O     . GLY B 1 29  ? 378.102 352.457 233.258 1.00 123.93 ? 29  GLY E O     1 
ATOM   3557  N  N     . ILE B 1 30  ? 379.304 353.888 234.525 1.00 105.60 ? 30  ILE E N     1 
ATOM   3558  C  CA    . ILE B 1 30  ? 379.968 352.872 235.337 1.00 103.41 ? 30  ILE E CA    1 
ATOM   3559  C  C     . ILE B 1 30  ? 379.379 352.941 236.739 1.00 106.66 ? 30  ILE E C     1 
ATOM   3560  O  O     . ILE B 1 30  ? 379.318 354.018 237.344 1.00 105.20 ? 30  ILE E O     1 
ATOM   3561  C  CB    . ILE B 1 30  ? 381.494 353.077 235.356 1.00 94.30  ? 30  ILE E CB    1 
ATOM   3562  C  CG1   . ILE B 1 30  ? 382.096 352.608 234.033 1.00 98.03  ? 30  ILE E CG1   1 
ATOM   3563  C  CG2   . ILE B 1 30  ? 382.157 352.307 236.507 1.00 97.58  ? 30  ILE E CG2   1 
ATOM   3564  C  CD1   . ILE B 1 30  ? 383.389 353.293 233.670 1.00 94.97  ? 30  ILE E CD1   1 
ATOM   3565  N  N     . ASP B 1 31  ? 378.951 351.791 237.253 1.00 118.08 ? 31  ASP E N     1 
ATOM   3566  C  CA    . ASP B 1 31  ? 378.395 351.710 238.587 1.00 111.42 ? 31  ASP E CA    1 
ATOM   3567  C  C     . ASP B 1 31  ? 379.510 351.903 239.612 1.00 108.41 ? 31  ASP E C     1 
ATOM   3568  O  O     . ASP B 1 31  ? 380.692 351.873 239.263 1.00 110.70 ? 31  ASP E O     1 
ATOM   3569  C  CB    . ASP B 1 31  ? 377.698 350.365 238.785 1.00 110.51 ? 31  ASP E CB    1 
ATOM   3570  C  CG    . ASP B 1 31  ? 376.444 350.232 237.949 1.00 117.00 ? 31  ASP E CG    1 
ATOM   3571  O  OD1   . ASP B 1 31  ? 376.229 351.081 237.060 1.00 115.87 ? 31  ASP E OD1   1 
ATOM   3572  O  OD2   . ASP B 1 31  ? 375.670 349.282 238.186 1.00 115.78 ? 31  ASP E OD2   1 
ATOM   3573  N  N     . PRO B 1 32  ? 379.170 352.127 240.888 1.00 104.71 ? 32  PRO E N     1 
ATOM   3574  C  CA    . PRO B 1 32  ? 380.225 352.206 241.914 1.00 107.93 ? 32  PRO E CA    1 
ATOM   3575  C  C     . PRO B 1 32  ? 381.039 350.933 242.054 1.00 106.08 ? 32  PRO E C     1 
ATOM   3576  O  O     . PRO B 1 32  ? 382.191 350.998 242.499 1.00 103.53 ? 32  PRO E O     1 
ATOM   3577  C  CB    . PRO B 1 32  ? 379.446 352.510 243.201 1.00 108.88 ? 32  PRO E CB    1 
ATOM   3578  C  CG    . PRO B 1 32  ? 378.171 353.098 242.750 1.00 106.68 ? 32  PRO E CG    1 
ATOM   3579  C  CD    . PRO B 1 32  ? 377.844 352.422 241.462 1.00 103.43 ? 32  PRO E CD    1 
ATOM   3580  N  N     . THR B 1 33  ? 380.482 349.778 241.690 1.00 112.22 ? 33  THR E N     1 
ATOM   3581  C  CA    . THR B 1 33  ? 381.231 348.529 241.706 1.00 108.82 ? 33  THR E CA    1 
ATOM   3582  C  C     . THR B 1 33  ? 382.293 348.449 240.615 1.00 107.38 ? 33  THR E C     1 
ATOM   3583  O  O     . THR B 1 33  ? 383.118 347.530 240.658 1.00 110.47 ? 33  THR E O     1 
ATOM   3584  C  CB    . THR B 1 33  ? 380.273 347.345 241.557 1.00 111.48 ? 33  THR E CB    1 
ATOM   3585  O  OG1   . THR B 1 33  ? 379.555 347.459 240.322 1.00 108.54 ? 33  THR E OG1   1 
ATOM   3586  C  CG2   . THR B 1 33  ? 379.285 347.300 242.714 1.00 111.85 ? 33  THR E CG2   1 
ATOM   3587  N  N     . GLY B 1 34  ? 382.297 349.371 239.647 1.00 99.64  ? 34  GLY E N     1 
ATOM   3588  C  CA    . GLY B 1 34  ? 383.218 349.329 238.532 1.00 100.65 ? 34  GLY E CA    1 
ATOM   3589  C  C     . GLY B 1 34  ? 382.709 348.600 237.307 1.00 96.92  ? 34  GLY E C     1 
ATOM   3590  O  O     . GLY B 1 34  ? 383.397 348.602 236.279 1.00 96.41  ? 34  GLY E O     1 
ATOM   3591  N  N     . THR B 1 35  ? 381.536 347.975 237.377 1.00 98.81  ? 35  THR E N     1 
ATOM   3592  C  CA    . THR B 1 35  ? 380.942 347.341 236.211 1.00 101.06 ? 35  THR E CA    1 
ATOM   3593  C  C     . THR B 1 35  ? 380.297 348.392 235.318 1.00 103.92 ? 35  THR E C     1 
ATOM   3594  O  O     . THR B 1 35  ? 379.690 349.351 235.802 1.00 110.24 ? 35  THR E O     1 
ATOM   3595  C  CB    . THR B 1 35  ? 379.897 346.309 236.639 1.00 106.34 ? 35  THR E CB    1 
ATOM   3596  O  OG1   . THR B 1 35  ? 380.426 345.502 237.698 1.00 105.40 ? 35  THR E OG1   1 
ATOM   3597  C  CG2   . THR B 1 35  ? 379.507 345.411 235.469 1.00 104.64 ? 35  THR E CG2   1 
ATOM   3598  N  N     . TYR B 1 36  ? 380.433 348.206 234.009 1.00 98.04  ? 36  TYR E N     1 
ATOM   3599  C  CA    . TYR B 1 36  ? 379.840 349.121 233.046 1.00 98.11  ? 36  TYR E CA    1 
ATOM   3600  C  C     . TYR B 1 36  ? 378.362 348.811 232.857 1.00 102.52 ? 36  TYR E C     1 
ATOM   3601  O  O     . TYR B 1 36  ? 377.967 347.648 232.737 1.00 101.79 ? 36  TYR E O     1 
ATOM   3602  C  CB    . TYR B 1 36  ? 380.566 349.025 231.706 1.00 99.22  ? 36  TYR E CB    1 
ATOM   3603  C  CG    . TYR B 1 36  ? 379.937 349.848 230.607 1.00 98.26  ? 36  TYR E CG    1 
ATOM   3604  C  CD1   . TYR B 1 36  ? 380.178 351.210 230.511 1.00 98.49  ? 36  TYR E CD1   1 
ATOM   3605  C  CD2   . TYR B 1 36  ? 379.112 349.262 229.655 1.00 99.87  ? 36  TYR E CD2   1 
ATOM   3606  C  CE1   . TYR B 1 36  ? 379.610 351.966 229.507 1.00 99.53  ? 36  TYR E CE1   1 
ATOM   3607  C  CE2   . TYR B 1 36  ? 378.536 350.010 228.655 1.00 102.11 ? 36  TYR E CE2   1 
ATOM   3608  C  CZ    . TYR B 1 36  ? 378.789 351.361 228.583 1.00 101.15 ? 36  TYR E CZ    1 
ATOM   3609  O  OH    . TYR B 1 36  ? 378.221 352.108 227.577 1.00 108.31 ? 36  TYR E OH    1 
ATOM   3610  N  N     . HIS B 1 37  ? 377.540 349.869 232.846 1.00 119.28 ? 37  HIS E N     1 
ATOM   3611  C  CA    . HIS B 1 37  ? 376.122 349.748 232.522 1.00 117.14 ? 37  HIS E CA    1 
ATOM   3612  C  C     . HIS B 1 37  ? 375.624 350.927 231.684 1.00 116.49 ? 37  HIS E C     1 
ATOM   3613  O  O     . HIS B 1 37  ? 374.418 351.200 231.664 1.00 112.34 ? 37  HIS E O     1 
ATOM   3614  C  CB    . HIS B 1 37  ? 375.301 349.601 233.813 1.00 112.74 ? 37  HIS E CB    1 
ATOM   3615  C  CG    . HIS B 1 37  ? 375.469 348.271 234.478 1.00 118.34 ? 37  HIS E CG    1 
ATOM   3616  N  ND1   . HIS B 1 37  ? 374.783 347.146 234.071 1.00 122.29 ? 37  HIS E ND1   1 
ATOM   3617  C  CD2   . HIS B 1 37  ? 376.253 347.881 235.509 1.00 118.11 ? 37  HIS E CD2   1 
ATOM   3618  C  CE1   . HIS B 1 37  ? 375.132 346.123 234.830 1.00 121.72 ? 37  HIS E CE1   1 
ATOM   3619  N  NE2   . HIS B 1 37  ? 376.023 346.542 235.710 1.00 120.72 ? 37  HIS E NE2   1 
ATOM   3620  N  N     . GLY B 1 38  ? 376.515 351.620 230.971 1.00 121.11 ? 38  GLY E N     1 
ATOM   3621  C  CA    . GLY B 1 38  ? 376.101 352.717 230.125 1.00 118.56 ? 38  GLY E CA    1 
ATOM   3622  C  C     . GLY B 1 38  ? 375.468 352.240 228.832 1.00 121.60 ? 38  GLY E C     1 
ATOM   3623  O  O     . GLY B 1 38  ? 375.426 351.047 228.533 1.00 122.19 ? 38  GLY E O     1 
ATOM   3624  N  N     . ASP B 1 39  ? 374.979 353.209 228.057 1.00 136.46 ? 39  ASP E N     1 
ATOM   3625  C  CA    . ASP B 1 39  ? 374.255 352.958 226.814 1.00 137.21 ? 39  ASP E CA    1 
ATOM   3626  C  C     . ASP B 1 39  ? 375.086 353.224 225.566 1.00 135.62 ? 39  ASP E C     1 
ATOM   3627  O  O     . ASP B 1 39  ? 374.888 352.554 224.548 1.00 135.01 ? 39  ASP E O     1 
ATOM   3628  C  CB    . ASP B 1 39  ? 372.983 353.813 226.765 1.00 138.27 ? 39  ASP E CB    1 
ATOM   3629  C  CG    . ASP B 1 39  ? 373.278 355.300 226.743 1.00 138.90 ? 39  ASP E CG    1 
ATOM   3630  O  OD1   . ASP B 1 39  ? 373.549 355.869 227.822 1.00 138.76 ? 39  ASP E OD1   1 
ATOM   3631  O  OD2   . ASP B 1 39  ? 373.241 355.899 225.648 1.00 136.82 ? 39  ASP E OD2   1 
ATOM   3632  N  N     . SER B 1 40  ? 376.015 354.177 225.619 1.00 135.61 ? 40  SER E N     1 
ATOM   3633  C  CA    . SER B 1 40  ? 376.752 354.615 224.440 1.00 133.78 ? 40  SER E CA    1 
ATOM   3634  C  C     . SER B 1 40  ? 378.048 353.831 224.281 1.00 132.17 ? 40  SER E C     1 
ATOM   3635  O  O     . SER B 1 40  ? 378.740 353.540 225.260 1.00 136.86 ? 40  SER E O     1 
ATOM   3636  C  CB    . SER B 1 40  ? 377.061 356.109 224.532 1.00 133.28 ? 40  SER E CB    1 
ATOM   3637  O  OG    . SER B 1 40  ? 375.869 356.869 224.616 1.00 135.50 ? 40  SER E OG    1 
ATOM   3638  N  N     . ASP B 1 41  ? 378.371 353.494 223.030 1.00 125.65 ? 41  ASP E N     1 
ATOM   3639  C  CA    . ASP B 1 41  ? 379.636 352.837 222.722 1.00 127.35 ? 41  ASP E CA    1 
ATOM   3640  C  C     . ASP B 1 41  ? 380.805 353.812 222.863 1.00 129.08 ? 41  ASP E C     1 
ATOM   3641  O  O     . ASP B 1 41  ? 381.919 353.398 223.220 1.00 130.63 ? 41  ASP E O     1 
ATOM   3642  C  CB    . ASP B 1 41  ? 379.557 352.258 221.302 1.00 129.85 ? 41  ASP E CB    1 
ATOM   3643  C  CG    . ASP B 1 41  ? 380.739 351.359 220.935 1.00 130.32 ? 41  ASP E CG    1 
ATOM   3644  O  OD1   . ASP B 1 41  ? 381.722 351.250 221.693 1.00 129.02 ? 41  ASP E OD1   1 
ATOM   3645  O  OD2   . ASP B 1 41  ? 380.675 350.743 219.851 1.00 131.18 ? 41  ASP E OD2   1 
ATOM   3646  N  N     . LEU B 1 42  ? 380.561 355.106 222.632 1.00 119.86 ? 42  LEU E N     1 
ATOM   3647  C  CA    . LEU B 1 42  ? 381.601 356.118 222.767 1.00 120.13 ? 42  LEU E CA    1 
ATOM   3648  C  C     . LEU B 1 42  ? 382.150 356.199 224.186 1.00 119.74 ? 42  LEU E C     1 
ATOM   3649  O  O     . LEU B 1 42  ? 383.294 356.628 224.369 1.00 121.03 ? 42  LEU E O     1 
ATOM   3650  C  CB    . LEU B 1 42  ? 381.056 357.485 222.344 1.00 119.02 ? 42  LEU E CB    1 
ATOM   3651  C  CG    . LEU B 1 42  ? 380.527 357.602 220.909 1.00 118.21 ? 42  LEU E CG    1 
ATOM   3652  C  CD1   . LEU B 1 42  ? 379.732 358.888 220.739 1.00 114.80 ? 42  LEU E CD1   1 
ATOM   3653  C  CD2   . LEU B 1 42  ? 381.652 357.515 219.889 1.00 118.02 ? 42  LEU E CD2   1 
ATOM   3654  N  N     . GLN B 1 43  ? 381.363 355.803 225.189 1.00 110.78 ? 43  GLN E N     1 
ATOM   3655  C  CA    . GLN B 1 43  ? 381.886 355.712 226.547 1.00 106.85 ? 43  GLN E CA    1 
ATOM   3656  C  C     . GLN B 1 43  ? 382.998 354.675 226.639 1.00 103.99 ? 43  GLN E C     1 
ATOM   3657  O  O     . GLN B 1 43  ? 384.039 354.927 227.256 1.00 103.20 ? 43  GLN E O     1 
ATOM   3658  C  CB    . GLN B 1 43  ? 380.756 355.371 227.518 1.00 106.41 ? 43  GLN E CB    1 
ATOM   3659  C  CG    . GLN B 1 43  ? 379.706 356.463 227.657 1.00 106.39 ? 43  GLN E CG    1 
ATOM   3660  C  CD    . GLN B 1 43  ? 378.464 355.992 228.384 1.00 108.31 ? 43  GLN E CD    1 
ATOM   3661  O  OE1   . GLN B 1 43  ? 377.990 354.878 228.168 1.00 114.01 ? 43  GLN E OE1   1 
ATOM   3662  N  NE2   . GLN B 1 43  ? 377.925 356.844 229.247 1.00 110.57 ? 43  GLN E NE2   1 
ATOM   3663  N  N     . LEU B 1 44  ? 382.802 353.504 226.026 1.00 105.88 ? 44  LEU E N     1 
ATOM   3664  C  CA    . LEU B 1 44  ? 383.844 352.484 226.034 1.00 107.67 ? 44  LEU E CA    1 
ATOM   3665  C  C     . LEU B 1 44  ? 384.997 352.821 225.103 1.00 112.18 ? 44  LEU E C     1 
ATOM   3666  O  O     . LEU B 1 44  ? 386.099 352.299 225.303 1.00 113.69 ? 44  LEU E O     1 
ATOM   3667  C  CB    . LEU B 1 44  ? 383.295 351.115 225.619 1.00 110.09 ? 44  LEU E CB    1 
ATOM   3668  C  CG    . LEU B 1 44  ? 382.167 350.411 226.384 1.00 110.52 ? 44  LEU E CG    1 
ATOM   3669  C  CD1   . LEU B 1 44  ? 382.300 350.600 227.888 1.00 101.76 ? 44  LEU E CD1   1 
ATOM   3670  C  CD2   . LEU B 1 44  ? 380.785 350.830 225.892 1.00 111.54 ? 44  LEU E CD2   1 
ATOM   3671  N  N     . ASP B 1 45  ? 384.763 353.648 224.077 1.00 119.40 ? 45  ASP E N     1 
ATOM   3672  C  CA    . ASP B 1 45  ? 385.804 353.902 223.082 1.00 118.49 ? 45  ASP E CA    1 
ATOM   3673  C  C     . ASP B 1 45  ? 387.029 354.576 223.693 1.00 117.62 ? 45  ASP E C     1 
ATOM   3674  O  O     . ASP B 1 45  ? 388.165 354.213 223.366 1.00 114.48 ? 45  ASP E O     1 
ATOM   3675  C  CB    . ASP B 1 45  ? 385.243 354.750 221.941 1.00 118.39 ? 45  ASP E CB    1 
ATOM   3676  C  CG    . ASP B 1 45  ? 384.175 354.024 221.147 1.00 122.00 ? 45  ASP E CG    1 
ATOM   3677  O  OD1   . ASP B 1 45  ? 383.913 352.840 221.442 1.00 124.29 ? 45  ASP E OD1   1 
ATOM   3678  O  OD2   . ASP B 1 45  ? 383.599 354.637 220.225 1.00 122.12 ? 45  ASP E OD2   1 
ATOM   3679  N  N     . ARG B 1 46  ? 386.818 355.551 224.585 1.00 109.98 ? 46  ARG E N     1 
ATOM   3680  C  CA    . ARG B 1 46  ? 387.890 356.304 225.233 1.00 106.60 ? 46  ARG E CA    1 
ATOM   3681  C  C     . ARG B 1 46  ? 387.942 356.069 226.740 1.00 103.67 ? 46  ARG E C     1 
ATOM   3682  O  O     . ARG B 1 46  ? 388.450 356.919 227.477 1.00 103.86 ? 46  ARG E O     1 
ATOM   3683  C  CB    . ARG B 1 46  ? 387.738 357.801 224.949 1.00 108.05 ? 46  ARG E CB    1 
ATOM   3684  C  CG    . ARG B 1 46  ? 387.695 358.204 223.474 1.00 107.37 ? 46  ARG E CG    1 
ATOM   3685  C  CD    . ARG B 1 46  ? 389.066 358.134 222.815 1.00 106.46 ? 46  ARG E CD    1 
ATOM   3686  N  NE    . ARG B 1 46  ? 388.959 357.858 221.386 1.00 107.82 ? 46  ARG E NE    1 
ATOM   3687  C  CZ    . ARG B 1 46  ? 389.915 357.337 220.624 1.00 107.06 ? 46  ARG E CZ    1 
ATOM   3688  N  NH1   . ARG B 1 46  ? 391.116 357.045 221.101 1.00 105.61 ? 46  ARG E NH1   1 
ATOM   3689  N  NH2   . ARG B 1 46  ? 389.660 357.106 219.340 1.00 107.48 ? 46  ARG E NH2   1 
ATOM   3690  N  N     . ILE B 1 47  ? 387.430 354.933 227.219 1.00 99.06  ? 47  ILE E N     1 
ATOM   3691  C  CA    . ILE B 1 47  ? 387.496 354.648 228.646 1.00 95.95  ? 47  ILE E CA    1 
ATOM   3692  C  C     . ILE B 1 47  ? 388.929 354.413 229.109 1.00 98.54  ? 47  ILE E C     1 
ATOM   3693  O  O     . ILE B 1 47  ? 389.228 354.597 230.294 1.00 102.75 ? 47  ILE E O     1 
ATOM   3694  C  CB    . ILE B 1 47  ? 386.587 353.450 228.991 1.00 102.72 ? 47  ILE E CB    1 
ATOM   3695  C  CG1   . ILE B 1 47  ? 386.149 353.518 230.456 1.00 98.01  ? 47  ILE E CG1   1 
ATOM   3696  C  CG2   . ILE B 1 47  ? 387.264 352.112 228.675 1.00 102.57 ? 47  ILE E CG2   1 
ATOM   3697  C  CD1   . ILE B 1 47  ? 384.967 354.430 230.695 1.00 98.27  ? 47  ILE E CD1   1 
ATOM   3698  N  N     . SER B 1 48  ? 389.831 354.021 228.205 1.00 104.08 ? 48  SER E N     1 
ATOM   3699  C  CA    . SER B 1 48  ? 391.226 353.803 228.575 1.00 106.17 ? 48  SER E CA    1 
ATOM   3700  C  C     . SER B 1 48  ? 391.944 355.082 228.997 1.00 102.80 ? 48  SER E C     1 
ATOM   3701  O  O     . SER B 1 48  ? 393.023 354.992 229.590 1.00 105.78 ? 48  SER E O     1 
ATOM   3702  C  CB    . SER B 1 48  ? 391.976 353.164 227.407 1.00 106.69 ? 48  SER E CB    1 
ATOM   3703  O  OG    . SER B 1 48  ? 391.901 353.978 226.250 1.00 106.64 ? 48  SER E OG    1 
ATOM   3704  N  N     . VAL B 1 49  ? 391.385 356.259 228.694 1.00 100.45 ? 49  VAL E N     1 
ATOM   3705  C  CA    . VAL B 1 49  ? 392.041 357.522 229.026 1.00 100.08 ? 49  VAL E CA    1 
ATOM   3706  C  C     . VAL B 1 49  ? 392.193 357.673 230.535 1.00 101.10 ? 49  VAL E C     1 
ATOM   3707  O  O     . VAL B 1 49  ? 393.241 358.114 231.023 1.00 107.64 ? 49  VAL E O     1 
ATOM   3708  C  CB    . VAL B 1 49  ? 391.256 358.700 228.415 1.00 99.27  ? 49  VAL E CB    1 
ATOM   3709  C  CG1   . VAL B 1 49  ? 391.797 360.040 228.918 1.00 96.73  ? 49  VAL E CG1   1 
ATOM   3710  C  CG2   . VAL B 1 49  ? 391.296 358.636 226.887 1.00 102.45 ? 49  VAL E CG2   1 
ATOM   3711  N  N     . TYR B 1 50  ? 391.155 357.302 231.294 1.00 90.13  ? 50  TYR E N     1 
ATOM   3712  C  CA    . TYR B 1 50  ? 391.109 357.447 232.747 1.00 85.43  ? 50  TYR E CA    1 
ATOM   3713  C  C     . TYR B 1 50  ? 391.055 356.135 233.512 1.00 92.86  ? 50  TYR E C     1 
ATOM   3714  O  O     . TYR B 1 50  ? 391.400 356.128 234.695 1.00 94.87  ? 50  TYR E O     1 
ATOM   3715  C  CB    . TYR B 1 50  ? 389.887 358.285 233.159 1.00 88.47  ? 50  TYR E CB    1 
ATOM   3716  C  CG    . TYR B 1 50  ? 390.134 359.774 233.250 1.00 89.69  ? 50  TYR E CG    1 
ATOM   3717  C  CD1   . TYR B 1 50  ? 390.979 360.301 234.216 1.00 93.69  ? 50  TYR E CD1   1 
ATOM   3718  C  CD2   . TYR B 1 50  ? 389.508 360.655 232.383 1.00 89.73  ? 50  TYR E CD2   1 
ATOM   3719  C  CE1   . TYR B 1 50  ? 391.204 361.650 234.307 1.00 92.75  ? 50  TYR E CE1   1 
ATOM   3720  C  CE2   . TYR B 1 50  ? 389.727 362.013 232.469 1.00 89.30  ? 50  TYR E CE2   1 
ATOM   3721  C  CZ    . TYR B 1 50  ? 390.580 362.503 233.433 1.00 88.77  ? 50  TYR E CZ    1 
ATOM   3722  O  OH    . TYR B 1 50  ? 390.809 363.852 233.545 1.00 95.03  ? 50  TYR E OH    1 
ATOM   3723  N  N     . TYR B 1 51  ? 390.644 355.038 232.877 1.00 98.85  ? 51  TYR E N     1 
ATOM   3724  C  CA    . TYR B 1 51  ? 390.424 353.757 233.534 1.00 94.17  ? 51  TYR E CA    1 
ATOM   3725  C  C     . TYR B 1 51  ? 391.331 352.689 232.943 1.00 90.81  ? 51  TYR E C     1 
ATOM   3726  O  O     . TYR B 1 51  ? 391.748 352.776 231.784 1.00 95.10  ? 51  TYR E O     1 
ATOM   3727  C  CB    . TYR B 1 51  ? 388.963 353.319 233.392 1.00 95.50  ? 51  TYR E CB    1 
ATOM   3728  C  CG    . TYR B 1 51  ? 387.990 354.169 234.171 1.00 89.29  ? 51  TYR E CG    1 
ATOM   3729  C  CD1   . TYR B 1 51  ? 387.647 353.842 235.472 1.00 91.63  ? 51  TYR E CD1   1 
ATOM   3730  C  CD2   . TYR B 1 51  ? 387.431 355.308 233.613 1.00 86.11  ? 51  TYR E CD2   1 
ATOM   3731  C  CE1   . TYR B 1 51  ? 386.763 354.614 236.191 1.00 94.57  ? 51  TYR E CE1   1 
ATOM   3732  C  CE2   . TYR B 1 51  ? 386.547 356.089 234.326 1.00 88.04  ? 51  TYR E CE2   1 
ATOM   3733  C  CZ    . TYR B 1 51  ? 386.219 355.737 235.617 1.00 93.62  ? 51  TYR E CZ    1 
ATOM   3734  O  OH    . TYR B 1 51  ? 385.337 356.502 236.342 1.00 94.79  ? 51  TYR E OH    1 
ATOM   3735  N  N     . ASN B 1 52  ? 391.651 351.698 233.771 1.00 91.81  ? 52  ASN E N     1 
ATOM   3736  C  CA    . ASN B 1 52  ? 392.255 350.448 233.330 1.00 99.46  ? 52  ASN E CA    1 
ATOM   3737  C  C     . ASN B 1 52  ? 391.209 349.344 233.386 1.00 102.64 ? 52  ASN E C     1 
ATOM   3738  O  O     . ASN B 1 52  ? 390.462 349.230 234.367 1.00 101.83 ? 52  ASN E O     1 
ATOM   3739  C  CB    . ASN B 1 52  ? 393.468 350.070 234.182 1.00 101.16 ? 52  ASN E CB    1 
ATOM   3740  C  CG    . ASN B 1 52  ? 394.602 351.061 234.054 1.00 105.57 ? 52  ASN E CG    1 
ATOM   3741  O  OD1   . ASN B 1 52  ? 394.742 351.729 233.033 1.00 114.11 ? 52  ASN E OD1   1 
ATOM   3742  N  ND2   . ASN B 1 52  ? 395.433 351.145 235.085 1.00 102.12 ? 52  ASN E ND2   1 
ATOM   3743  N  N     . GLU B 1 53  ? 391.161 348.542 232.326 1.00 121.19 ? 53  GLU E N     1 
ATOM   3744  C  CA    . GLU B 1 53  ? 390.185 347.467 232.175 1.00 121.70 ? 53  GLU E CA    1 
ATOM   3745  C  C     . GLU B 1 53  ? 390.713 346.235 232.897 1.00 124.97 ? 53  GLU E C     1 
ATOM   3746  O  O     . GLU B 1 53  ? 391.589 345.530 232.391 1.00 126.48 ? 53  GLU E O     1 
ATOM   3747  C  CB    . GLU B 1 53  ? 389.935 347.202 230.691 1.00 120.93 ? 53  GLU E CB    1 
ATOM   3748  C  CG    . GLU B 1 53  ? 389.271 345.870 230.318 1.00 123.23 ? 53  GLU E CG    1 
ATOM   3749  C  CD    . GLU B 1 53  ? 387.990 345.589 231.078 1.00 126.78 ? 53  GLU E CD    1 
ATOM   3750  O  OE1   . GLU B 1 53  ? 387.368 346.541 231.592 1.00 123.23 ? 53  GLU E OE1   1 
ATOM   3751  O  OE2   . GLU B 1 53  ? 387.595 344.407 231.147 1.00 128.05 ? 53  GLU E OE2   1 
ATOM   3752  N  N     . ALA B 1 54  ? 390.184 345.978 234.091 1.00 135.37 ? 54  ALA E N     1 
ATOM   3753  C  CA    . ALA B 1 54  ? 390.530 344.782 234.839 1.00 133.11 ? 54  ALA E CA    1 
ATOM   3754  C  C     . ALA B 1 54  ? 389.753 343.582 234.300 1.00 134.57 ? 54  ALA E C     1 
ATOM   3755  O  O     . ALA B 1 54  ? 388.903 343.703 233.415 1.00 138.31 ? 54  ALA E O     1 
ATOM   3756  C  CB    . ALA B 1 54  ? 390.248 344.979 236.328 1.00 133.87 ? 54  ALA E CB    1 
ATOM   3757  N  N     . THR B 1 55  ? 390.061 342.409 234.846 1.00 146.52 ? 55  THR E N     1 
ATOM   3758  C  CA    . THR B 1 55  ? 389.429 341.179 234.386 1.00 149.18 ? 55  THR E CA    1 
ATOM   3759  C  C     . THR B 1 55  ? 387.944 341.191 234.733 1.00 148.69 ? 55  THR E C     1 
ATOM   3760  O  O     . THR B 1 55  ? 387.545 341.627 235.816 1.00 149.55 ? 55  THR E O     1 
ATOM   3761  C  CB    . THR B 1 55  ? 390.129 339.967 235.014 1.00 148.95 ? 55  THR E CB    1 
ATOM   3762  O  OG1   . THR B 1 55  ? 391.390 339.759 234.366 1.00 146.86 ? 55  THR E OG1   1 
ATOM   3763  C  CG2   . THR B 1 55  ? 389.299 338.682 234.875 1.00 147.40 ? 55  THR E CG2   1 
ATOM   3764  N  N     . GLY B 1 56  ? 387.125 340.713 233.799 1.00 150.42 ? 56  GLY E N     1 
ATOM   3765  C  CA    . GLY B 1 56  ? 385.696 340.625 234.020 1.00 149.70 ? 56  GLY E CA    1 
ATOM   3766  C  C     . GLY B 1 56  ? 384.924 341.896 233.758 1.00 152.71 ? 56  GLY E C     1 
ATOM   3767  O  O     . GLY B 1 56  ? 383.829 342.062 234.303 1.00 154.05 ? 56  GLY E O     1 
ATOM   3768  N  N     . GLY B 1 57  ? 385.456 342.802 232.942 1.00 142.54 ? 57  GLY E N     1 
ATOM   3769  C  CA    . GLY B 1 57  ? 384.763 344.035 232.631 1.00 141.60 ? 57  GLY E CA    1 
ATOM   3770  C  C     . GLY B 1 57  ? 384.787 345.085 233.718 1.00 140.26 ? 57  GLY E C     1 
ATOM   3771  O  O     . GLY B 1 57  ? 384.096 346.101 233.584 1.00 138.22 ? 57  GLY E O     1 
ATOM   3772  N  N     . LYS B 1 58  ? 385.555 344.881 234.787 1.00 128.36 ? 58  LYS E N     1 
ATOM   3773  C  CA    . LYS B 1 58  ? 385.648 345.859 235.860 1.00 126.96 ? 58  LYS E CA    1 
ATOM   3774  C  C     . LYS B 1 58  ? 386.656 346.937 235.482 1.00 125.36 ? 58  LYS E C     1 
ATOM   3775  O  O     . LYS B 1 58  ? 387.783 346.629 235.083 1.00 128.87 ? 58  LYS E O     1 
ATOM   3776  C  CB    . LYS B 1 58  ? 386.062 345.176 237.162 1.00 126.97 ? 58  LYS E CB    1 
ATOM   3777  C  CG    . LYS B 1 58  ? 385.752 345.977 238.411 1.00 128.05 ? 58  LYS E CG    1 
ATOM   3778  C  CD    . LYS B 1 58  ? 386.371 345.339 239.642 1.00 133.23 ? 58  LYS E CD    1 
ATOM   3779  C  CE    . LYS B 1 58  ? 385.841 345.969 240.918 1.00 131.85 ? 58  LYS E CE    1 
ATOM   3780  N  NZ    . LYS B 1 58  ? 384.495 345.442 241.275 1.00 130.55 ? 58  LYS E NZ    1 
ATOM   3781  N  N     . TYR B 1 59  ? 386.246 348.199 235.611 1.00 102.74 ? 59  TYR E N     1 
ATOM   3782  C  CA    . TYR B 1 59  ? 387.045 349.358 235.216 1.00 101.48 ? 59  TYR E CA    1 
ATOM   3783  C  C     . TYR B 1 59  ? 387.534 350.067 236.471 1.00 101.16 ? 59  TYR E C     1 
ATOM   3784  O  O     . TYR B 1 59  ? 386.737 350.692 237.178 1.00 102.89 ? 59  TYR E O     1 
ATOM   3785  C  CB    . TYR B 1 59  ? 386.218 350.304 234.352 1.00 97.26  ? 59  TYR E CB    1 
ATOM   3786  C  CG    . TYR B 1 59  ? 385.922 349.760 232.981 1.00 99.44  ? 59  TYR E CG    1 
ATOM   3787  C  CD1   . TYR B 1 59  ? 386.853 349.863 231.961 1.00 101.60 ? 59  TYR E CD1   1 
ATOM   3788  C  CD2   . TYR B 1 59  ? 384.713 349.136 232.705 1.00 103.86 ? 59  TYR E CD2   1 
ATOM   3789  C  CE1   . TYR B 1 59  ? 386.591 349.368 230.705 1.00 103.99 ? 59  TYR E CE1   1 
ATOM   3790  C  CE2   . TYR B 1 59  ? 384.442 348.634 231.451 1.00 103.82 ? 59  TYR E CE2   1 
ATOM   3791  C  CZ    . TYR B 1 59  ? 385.386 348.753 230.453 1.00 107.75 ? 59  TYR E CZ    1 
ATOM   3792  O  OH    . TYR B 1 59  ? 385.127 348.257 229.197 1.00 112.47 ? 59  TYR E OH    1 
ATOM   3793  N  N     . VAL B 1 60  ? 388.838 349.987 236.734 1.00 93.83  ? 60  VAL E N     1 
ATOM   3794  C  CA    . VAL B 1 60  ? 389.434 350.638 237.903 1.00 94.81  ? 60  VAL E CA    1 
ATOM   3795  C  C     . VAL B 1 60  ? 389.915 352.024 237.469 1.00 97.40  ? 60  VAL E C     1 
ATOM   3796  O  O     . VAL B 1 60  ? 390.475 352.145 236.371 1.00 100.24 ? 60  VAL E O     1 
ATOM   3797  C  CB    . VAL B 1 60  ? 390.553 349.773 238.520 1.00 98.34  ? 60  VAL E CB    1 
ATOM   3798  C  CG1   . VAL B 1 60  ? 391.893 349.992 237.850 1.00 101.39 ? 60  VAL E CG1   1 
ATOM   3799  C  CG2   . VAL B 1 60  ? 390.686 350.062 240.012 1.00 99.55  ? 60  VAL E CG2   1 
ATOM   3800  N  N     . PRO B 1 61  ? 389.727 353.094 238.249 1.00 97.01  ? 61  PRO E N     1 
ATOM   3801  C  CA    . PRO B 1 61  ? 390.268 354.392 237.832 1.00 93.50  ? 61  PRO E CA    1 
ATOM   3802  C  C     . PRO B 1 61  ? 391.784 354.405 237.848 1.00 98.16  ? 61  PRO E C     1 
ATOM   3803  O  O     . PRO B 1 61  ? 392.427 353.692 238.620 1.00 100.31 ? 61  PRO E O     1 
ATOM   3804  C  CB    . PRO B 1 61  ? 389.711 355.369 238.874 1.00 90.82  ? 61  PRO E CB    1 
ATOM   3805  C  CG    . PRO B 1 61  ? 388.637 354.664 239.547 1.00 97.72  ? 61  PRO E CG    1 
ATOM   3806  C  CD    . PRO B 1 61  ? 388.986 353.229 239.512 1.00 102.44 ? 61  PRO E CD    1 
ATOM   3807  N  N     . ARG B 1 62  ? 392.350 355.247 236.985 1.00 111.34 ? 62  ARG E N     1 
ATOM   3808  C  CA    . ARG B 1 62  ? 393.783 355.545 237.009 1.00 109.31 ? 62  ARG E CA    1 
ATOM   3809  C  C     . ARG B 1 62  ? 394.062 356.691 237.985 1.00 104.57 ? 62  ARG E C     1 
ATOM   3810  O  O     . ARG B 1 62  ? 394.569 357.754 237.626 1.00 106.77 ? 62  ARG E O     1 
ATOM   3811  C  CB    . ARG B 1 62  ? 394.279 355.868 235.603 1.00 108.83 ? 62  ARG E CB    1 
ATOM   3812  C  CG    . ARG B 1 62  ? 395.783 355.715 235.437 1.00 110.06 ? 62  ARG E CG    1 
ATOM   3813  C  CD    . ARG B 1 62  ? 396.238 355.892 233.993 1.00 108.86 ? 62  ARG E CD    1 
ATOM   3814  N  NE    . ARG B 1 62  ? 395.876 354.761 233.140 1.00 105.57 ? 62  ARG E NE    1 
ATOM   3815  C  CZ    . ARG B 1 62  ? 394.811 354.681 232.348 1.00 107.08 ? 62  ARG E CZ    1 
ATOM   3816  N  NH1   . ARG B 1 62  ? 393.912 355.650 232.272 1.00 108.90 ? 62  ARG E NH1   1 
ATOM   3817  N  NH2   . ARG B 1 62  ? 394.637 353.588 231.610 1.00 110.22 ? 62  ARG E NH2   1 
ATOM   3818  N  N     . ALA B 1 63  ? 393.723 356.435 239.250 1.00 96.39  ? 63  ALA E N     1 
ATOM   3819  C  CA    . ALA B 1 63  ? 393.772 357.417 240.322 1.00 96.46  ? 63  ALA E CA    1 
ATOM   3820  C  C     . ALA B 1 63  ? 394.777 356.987 241.378 1.00 93.11  ? 63  ALA E C     1 
ATOM   3821  O  O     . ALA B 1 63  ? 395.018 355.794 241.583 1.00 99.00  ? 63  ALA E O     1 
ATOM   3822  C  CB    . ALA B 1 63  ? 392.397 357.597 240.969 1.00 101.27 ? 63  ALA E CB    1 
ATOM   3823  N  N     . ILE B 1 64  ? 395.368 357.982 242.035 1.00 102.59 ? 64  ILE E N     1 
ATOM   3824  C  CA    . ILE B 1 64  ? 396.333 357.787 243.112 1.00 100.98 ? 64  ILE E CA    1 
ATOM   3825  C  C     . ILE B 1 64  ? 395.916 358.703 244.253 1.00 103.40 ? 64  ILE E C     1 
ATOM   3826  O  O     . ILE B 1 64  ? 395.840 359.923 244.074 1.00 107.95 ? 64  ILE E O     1 
ATOM   3827  C  CB    . ILE B 1 64  ? 397.780 358.085 242.671 1.00 100.71 ? 64  ILE E CB    1 
ATOM   3828  C  CG1   . ILE B 1 64  ? 398.073 357.409 241.309 1.00 106.70 ? 64  ILE E CG1   1 
ATOM   3829  C  CG2   . ILE B 1 64  ? 398.761 357.683 243.808 1.00 97.49  ? 64  ILE E CG2   1 
ATOM   3830  C  CD1   . ILE B 1 64  ? 399.491 357.523 240.784 1.00 110.30 ? 64  ILE E CD1   1 
ATOM   3831  N  N     . LEU B 1 65  ? 395.666 358.120 245.421 1.00 102.20 ? 65  LEU E N     1 
ATOM   3832  C  CA    . LEU B 1 65  ? 395.093 358.822 246.562 1.00 102.39 ? 65  LEU E CA    1 
ATOM   3833  C  C     . LEU B 1 65  ? 396.157 358.932 247.645 1.00 105.36 ? 65  LEU E C     1 
ATOM   3834  O  O     . LEU B 1 65  ? 396.549 357.920 248.235 1.00 113.09 ? 65  LEU E O     1 
ATOM   3835  C  CB    . LEU B 1 65  ? 393.847 358.100 247.085 1.00 104.35 ? 65  LEU E CB    1 
ATOM   3836  C  CG    . LEU B 1 65  ? 392.977 357.310 246.094 1.00 108.57 ? 65  LEU E CG    1 
ATOM   3837  C  CD1   . LEU B 1 65  ? 391.988 356.462 246.840 1.00 107.82 ? 65  LEU E CD1   1 
ATOM   3838  C  CD2   . LEU B 1 65  ? 392.258 358.216 245.122 1.00 108.96 ? 65  LEU E CD2   1 
ATOM   3839  N  N     . VAL B 1 66  ? 396.609 360.160 247.904 1.00 98.36  ? 66  VAL E N     1 
ATOM   3840  C  CA    . VAL B 1 66  ? 397.682 360.445 248.851 1.00 99.61  ? 66  VAL E CA    1 
ATOM   3841  C  C     . VAL B 1 66  ? 397.142 361.383 249.921 1.00 101.93 ? 66  VAL E C     1 
ATOM   3842  O  O     . VAL B 1 66  ? 396.420 362.337 249.614 1.00 108.55 ? 66  VAL E O     1 
ATOM   3843  C  CB    . VAL B 1 66  ? 398.925 361.045 248.158 1.00 98.04  ? 66  VAL E CB    1 
ATOM   3844  C  CG1   . VAL B 1 66  ? 398.670 362.462 247.662 1.00 101.47 ? 66  VAL E CG1   1 
ATOM   3845  C  CG2   . VAL B 1 66  ? 400.130 361.015 249.092 1.00 99.53  ? 66  VAL E CG2   1 
ATOM   3846  N  N     . ASP B 1 67  ? 397.456 361.081 251.179 1.00 116.13 ? 67  ASP E N     1 
ATOM   3847  C  CA    . ASP B 1 67  ? 397.084 361.931 252.304 1.00 119.66 ? 67  ASP E CA    1 
ATOM   3848  C  C     . ASP B 1 67  ? 397.869 361.469 253.517 1.00 116.24 ? 67  ASP E C     1 
ATOM   3849  O  O     . ASP B 1 67  ? 397.892 360.274 253.819 1.00 120.99 ? 67  ASP E O     1 
ATOM   3850  C  CB    . ASP B 1 67  ? 395.574 361.868 252.600 1.00 124.12 ? 67  ASP E CB    1 
ATOM   3851  C  CG    . ASP B 1 67  ? 395.005 363.196 253.080 1.00 125.15 ? 67  ASP E CG    1 
ATOM   3852  O  OD1   . ASP B 1 67  ? 395.377 364.259 252.541 1.00 126.07 ? 67  ASP E OD1   1 
ATOM   3853  O  OD2   . ASP B 1 67  ? 394.177 363.173 254.015 1.00 122.50 ? 67  ASP E OD2   1 
ATOM   3854  N  N     . LEU B 1 68  ? 398.505 362.410 254.210 1.00 103.75 ? 68  LEU E N     1 
ATOM   3855  C  CA    . LEU B 1 68  ? 399.311 362.050 255.367 1.00 107.00 ? 68  LEU E CA    1 
ATOM   3856  C  C     . LEU B 1 68  ? 398.474 361.722 256.598 1.00 112.80 ? 68  LEU E C     1 
ATOM   3857  O  O     . LEU B 1 68  ? 399.009 361.121 257.536 1.00 116.63 ? 68  LEU E O     1 
ATOM   3858  C  CB    . LEU B 1 68  ? 400.292 363.176 255.677 1.00 106.96 ? 68  LEU E CB    1 
ATOM   3859  C  CG    . LEU B 1 68  ? 401.397 363.337 254.627 1.00 107.33 ? 68  LEU E CG    1 
ATOM   3860  C  CD1   . LEU B 1 68  ? 402.072 364.692 254.780 1.00 105.81 ? 68  LEU E CD1   1 
ATOM   3861  C  CD2   . LEU B 1 68  ? 402.407 362.190 254.675 1.00 112.13 ? 68  LEU E CD2   1 
ATOM   3862  N  N     . GLU B 1 69  ? 397.184 362.100 256.619 1.00 127.63 ? 69  GLU E N     1 
ATOM   3863  C  CA    . GLU B 1 69  ? 396.210 361.703 257.625 1.00 124.42 ? 69  GLU E CA    1 
ATOM   3864  C  C     . GLU B 1 69  ? 395.184 360.764 256.992 1.00 126.87 ? 69  GLU E C     1 
ATOM   3865  O  O     . GLU B 1 69  ? 394.959 360.827 255.780 1.00 132.98 ? 69  GLU E O     1 
ATOM   3866  C  CB    . GLU B 1 69  ? 395.495 362.920 258.230 1.00 128.86 ? 69  GLU E CB    1 
ATOM   3867  C  CG    . GLU B 1 69  ? 394.749 363.807 257.233 1.00 135.55 ? 69  GLU E CG    1 
ATOM   3868  C  CD    . GLU B 1 69  ? 394.194 365.060 257.877 1.00 135.99 ? 69  GLU E CD    1 
ATOM   3869  O  OE1   . GLU B 1 69  ? 394.056 365.077 259.117 1.00 133.74 ? 69  GLU E OE1   1 
ATOM   3870  O  OE2   . GLU B 1 69  ? 393.892 366.026 257.143 1.00 134.36 ? 69  GLU E OE2   1 
ATOM   3871  N  N     . PRO B 1 70  ? 394.543 359.883 257.762 1.00 115.70 ? 70  PRO E N     1 
ATOM   3872  C  CA    . PRO B 1 70  ? 393.723 358.834 257.149 1.00 115.71 ? 70  PRO E CA    1 
ATOM   3873  C  C     . PRO B 1 70  ? 392.281 359.214 256.861 1.00 114.06 ? 70  PRO E C     1 
ATOM   3874  O  O     . PRO B 1 70  ? 391.648 358.514 256.067 1.00 111.49 ? 70  PRO E O     1 
ATOM   3875  C  CB    . PRO B 1 70  ? 393.760 357.744 258.221 1.00 112.78 ? 70  PRO E CB    1 
ATOM   3876  C  CG    . PRO B 1 70  ? 393.653 358.538 259.484 1.00 116.83 ? 70  PRO E CG    1 
ATOM   3877  C  CD    . PRO B 1 70  ? 394.427 359.832 259.232 1.00 116.64 ? 70  PRO E CD    1 
ATOM   3878  N  N     . GLY B 1 71  ? 391.769 360.288 257.469 1.00 107.72 ? 71  GLY E N     1 
ATOM   3879  C  CA    . GLY B 1 71  ? 390.327 360.443 257.612 1.00 107.00 ? 71  GLY E CA    1 
ATOM   3880  C  C     . GLY B 1 71  ? 389.590 360.587 256.293 1.00 116.88 ? 71  GLY E C     1 
ATOM   3881  O  O     . GLY B 1 71  ? 388.580 359.916 256.061 1.00 121.58 ? 71  GLY E O     1 
ATOM   3882  N  N     . THR B 1 72  ? 390.085 361.454 255.408 1.00 126.90 ? 72  THR E N     1 
ATOM   3883  C  CA    . THR B 1 72  ? 389.415 361.638 254.125 1.00 129.07 ? 72  THR E CA    1 
ATOM   3884  C  C     . THR B 1 72  ? 389.495 360.382 253.268 1.00 130.72 ? 72  THR E C     1 
ATOM   3885  O  O     . THR B 1 72  ? 388.519 360.027 252.598 1.00 133.93 ? 72  THR E O     1 
ATOM   3886  C  CB    . THR B 1 72  ? 390.016 362.827 253.376 1.00 127.83 ? 72  THR E CB    1 
ATOM   3887  O  OG1   . THR B 1 72  ? 390.404 363.838 254.313 1.00 125.01 ? 72  THR E OG1   1 
ATOM   3888  C  CG2   . THR B 1 72  ? 389.002 363.407 252.396 1.00 129.75 ? 72  THR E CG2   1 
ATOM   3889  N  N     . MET B 1 73  ? 390.629 359.683 253.294 1.00 116.58 ? 73  MET E N     1 
ATOM   3890  C  CA    . MET B 1 73  ? 390.756 358.475 252.488 1.00 117.58 ? 73  MET E CA    1 
ATOM   3891  C  C     . MET B 1 73  ? 389.876 357.355 253.028 1.00 117.56 ? 73  MET E C     1 
ATOM   3892  O  O     . MET B 1 73  ? 389.297 356.588 252.253 1.00 111.61 ? 73  MET E O     1 
ATOM   3893  C  CB    . MET B 1 73  ? 392.214 358.034 252.432 1.00 114.99 ? 73  MET E CB    1 
ATOM   3894  C  CG    . MET B 1 73  ? 393.046 358.833 251.445 1.00 111.75 ? 73  MET E CG    1 
ATOM   3895  S  SD    . MET B 1 73  ? 394.808 358.517 251.607 1.00 122.95 ? 73  MET E SD    1 
ATOM   3896  C  CE    . MET B 1 73  ? 394.870 356.805 251.089 1.00 124.72 ? 73  MET E CE    1 
ATOM   3897  N  N     . ASP B 1 74  ? 389.769 357.238 254.352 1.00 114.00 ? 74  ASP E N     1 
ATOM   3898  C  CA    . ASP B 1 74  ? 388.859 356.259 254.936 1.00 113.48 ? 74  ASP E CA    1 
ATOM   3899  C  C     . ASP B 1 74  ? 387.414 356.603 254.615 1.00 111.41 ? 74  ASP E C     1 
ATOM   3900  O  O     . ASP B 1 74  ? 386.600 355.708 254.364 1.00 109.46 ? 74  ASP E O     1 
ATOM   3901  C  CB    . ASP B 1 74  ? 389.061 356.180 256.448 1.00 112.00 ? 74  ASP E CB    1 
ATOM   3902  C  CG    . ASP B 1 74  ? 390.440 355.686 256.828 1.00 114.32 ? 74  ASP E CG    1 
ATOM   3903  O  OD1   . ASP B 1 74  ? 391.139 355.128 255.958 1.00 117.60 ? 74  ASP E OD1   1 
ATOM   3904  O  OD2   . ASP B 1 74  ? 390.820 355.844 258.006 1.00 117.67 ? 74  ASP E OD2   1 
ATOM   3905  N  N     . SER B 1 75  ? 387.077 357.895 254.623 1.00 113.60 ? 75  SER E N     1 
ATOM   3906  C  CA    . SER B 1 75  ? 385.736 358.313 254.232 1.00 117.51 ? 75  SER E CA    1 
ATOM   3907  C  C     . SER B 1 75  ? 385.455 357.948 252.782 1.00 120.44 ? 75  SER E C     1 
ATOM   3908  O  O     . SER B 1 75  ? 384.350 357.508 252.447 1.00 128.12 ? 75  SER E O     1 
ATOM   3909  C  CB    . SER B 1 75  ? 385.578 359.817 254.447 1.00 120.52 ? 75  SER E CB    1 
ATOM   3910  O  OG    . SER B 1 75  ? 384.273 360.245 254.103 1.00 122.32 ? 75  SER E OG    1 
ATOM   3911  N  N     . VAL B 1 76  ? 386.447 358.119 251.909 1.00 100.66 ? 76  VAL E N     1 
ATOM   3912  C  CA    . VAL B 1 76  ? 386.276 357.746 250.509 1.00 104.28 ? 76  VAL E CA    1 
ATOM   3913  C  C     . VAL B 1 76  ? 386.119 356.235 250.375 1.00 111.07 ? 76  VAL E C     1 
ATOM   3914  O  O     . VAL B 1 76  ? 385.259 355.755 249.628 1.00 117.96 ? 76  VAL E O     1 
ATOM   3915  C  CB    . VAL B 1 76  ? 387.456 358.280 249.673 1.00 100.08 ? 76  VAL E CB    1 
ATOM   3916  C  CG1   . VAL B 1 76  ? 387.493 357.639 248.284 1.00 106.74 ? 76  VAL E CG1   1 
ATOM   3917  C  CG2   . VAL B 1 76  ? 387.370 359.793 249.542 1.00 99.35  ? 76  VAL E CG2   1 
ATOM   3918  N  N     . ARG B 1 77  ? 386.941 355.463 251.093 1.00 108.55 ? 77  ARG E N     1 
ATOM   3919  C  CA    . ARG B 1 77  ? 386.881 354.008 250.979 1.00 108.40 ? 77  ARG E CA    1 
ATOM   3920  C  C     . ARG B 1 77  ? 385.562 353.466 251.517 1.00 111.64 ? 77  ARG E C     1 
ATOM   3921  O  O     . ARG B 1 77  ? 385.023 352.489 250.985 1.00 115.69 ? 77  ARG E O     1 
ATOM   3922  C  CB    . ARG B 1 77  ? 388.059 353.359 251.708 1.00 109.23 ? 77  ARG E CB    1 
ATOM   3923  C  CG    . ARG B 1 77  ? 388.528 352.073 251.039 1.00 114.86 ? 77  ARG E CG    1 
ATOM   3924  C  CD    . ARG B 1 77  ? 389.574 351.313 251.847 1.00 116.76 ? 77  ARG E CD    1 
ATOM   3925  N  NE    . ARG B 1 77  ? 390.857 352.009 251.925 1.00 115.89 ? 77  ARG E NE    1 
ATOM   3926  C  CZ    . ARG B 1 77  ? 391.243 352.834 252.894 1.00 115.16 ? 77  ARG E CZ    1 
ATOM   3927  N  NH1   . ARG B 1 77  ? 390.449 353.154 253.906 1.00 118.65 ? 77  ARG E NH1   1 
ATOM   3928  N  NH2   . ARG B 1 77  ? 392.465 353.356 252.846 1.00 111.09 ? 77  ARG E NH2   1 
ATOM   3929  N  N     . SER B 1 78  ? 385.033 354.081 252.574 1.00 115.35 ? 78  SER E N     1 
ATOM   3930  C  CA    . SER B 1 78  ? 383.721 353.725 253.094 1.00 116.35 ? 78  SER E CA    1 
ATOM   3931  C  C     . SER B 1 78  ? 382.576 354.321 252.284 1.00 118.83 ? 78  SER E C     1 
ATOM   3932  O  O     . SER B 1 78  ? 381.429 353.899 252.467 1.00 127.18 ? 78  SER E O     1 
ATOM   3933  C  CB    . SER B 1 78  ? 383.601 354.178 254.550 1.00 118.85 ? 78  SER E CB    1 
ATOM   3934  O  OG    . SER B 1 78  ? 384.696 353.713 255.319 1.00 120.77 ? 78  SER E OG    1 
ATOM   3935  N  N     . GLY B 1 79  ? 382.849 355.286 251.399 1.00 118.62 ? 79  GLY E N     1 
ATOM   3936  C  CA    . GLY B 1 79  ? 381.817 355.891 250.611 1.00 118.14 ? 79  GLY E CA    1 
ATOM   3937  C  C     . GLY B 1 79  ? 381.282 354.942 249.554 1.00 128.56 ? 79  GLY E C     1 
ATOM   3938  O  O     . GLY B 1 79  ? 381.750 353.805 249.412 1.00 131.48 ? 79  GLY E O     1 
ATOM   3939  N  N     . PRO B 1 80  ? 380.270 355.403 248.808 1.00 137.36 ? 80  PRO E N     1 
ATOM   3940  C  CA    . PRO B 1 80  ? 379.654 354.523 247.797 1.00 134.50 ? 80  PRO E CA    1 
ATOM   3941  C  C     . PRO B 1 80  ? 380.609 354.095 246.694 1.00 132.00 ? 80  PRO E C     1 
ATOM   3942  O  O     . PRO B 1 80  ? 380.508 352.966 246.199 1.00 130.84 ? 80  PRO E O     1 
ATOM   3943  C  CB    . PRO B 1 80  ? 378.495 355.377 247.261 1.00 131.47 ? 80  PRO E CB    1 
ATOM   3944  C  CG    . PRO B 1 80  ? 378.917 356.780 247.495 1.00 128.82 ? 80  PRO E CG    1 
ATOM   3945  C  CD    . PRO B 1 80  ? 379.739 356.777 248.747 1.00 132.43 ? 80  PRO E CD    1 
ATOM   3946  N  N     . PHE B 1 81  ? 381.541 354.966 246.309 1.00 110.65 ? 81  PHE E N     1 
ATOM   3947  C  CA    . PHE B 1 81  ? 382.528 354.705 245.268 1.00 107.89 ? 81  PHE E CA    1 
ATOM   3948  C  C     . PHE B 1 81  ? 383.881 354.249 245.808 1.00 106.42 ? 81  PHE E C     1 
ATOM   3949  O  O     . PHE B 1 81  ? 384.823 354.101 245.025 1.00 106.58 ? 81  PHE E O     1 
ATOM   3950  C  CB    . PHE B 1 81  ? 382.685 355.959 244.405 1.00 105.47 ? 81  PHE E CB    1 
ATOM   3951  C  CG    . PHE B 1 81  ? 381.527 356.196 243.486 1.00 105.15 ? 81  PHE E CG    1 
ATOM   3952  C  CD1   . PHE B 1 81  ? 381.530 355.662 242.212 1.00 106.18 ? 81  PHE E CD1   1 
ATOM   3953  C  CD2   . PHE B 1 81  ? 380.400 356.864 243.920 1.00 106.13 ? 81  PHE E CD2   1 
ATOM   3954  C  CE1   . PHE B 1 81  ? 380.463 355.854 241.361 1.00 103.58 ? 81  PHE E CE1   1 
ATOM   3955  C  CE2   . PHE B 1 81  ? 379.323 357.048 243.076 1.00 112.24 ? 81  PHE E CE2   1 
ATOM   3956  C  CZ    . PHE B 1 81  ? 379.358 356.548 241.794 1.00 108.82 ? 81  PHE E CZ    1 
ATOM   3957  N  N     . GLY B 1 82  ? 383.991 353.985 247.112 1.00 114.07 ? 82  GLY E N     1 
ATOM   3958  C  CA    . GLY B 1 82  ? 385.245 353.495 247.659 1.00 114.87 ? 82  GLY E CA    1 
ATOM   3959  C  C     . GLY B 1 82  ? 385.668 352.158 247.086 1.00 118.36 ? 82  GLY E C     1 
ATOM   3960  O  O     . GLY B 1 82  ? 386.863 351.860 247.012 1.00 118.56 ? 82  GLY E O     1 
ATOM   3961  N  N     . GLN B 1 83  ? 384.703 351.337 246.673 1.00 114.91 ? 83  GLN E N     1 
ATOM   3962  C  CA    . GLN B 1 83  ? 385.025 350.075 246.025 1.00 112.17 ? 83  GLN E CA    1 
ATOM   3963  C  C     . GLN B 1 83  ? 385.710 350.262 244.678 1.00 112.93 ? 83  GLN E C     1 
ATOM   3964  O  O     . GLN B 1 83  ? 386.411 349.350 244.231 1.00 114.79 ? 83  GLN E O     1 
ATOM   3965  C  CB    . GLN B 1 83  ? 383.753 349.245 245.838 1.00 117.07 ? 83  GLN E CB    1 
ATOM   3966  C  CG    . GLN B 1 83  ? 384.000 347.754 245.665 1.00 123.58 ? 83  GLN E CG    1 
ATOM   3967  C  CD    . GLN B 1 83  ? 382.728 346.978 245.380 1.00 125.49 ? 83  GLN E CD    1 
ATOM   3968  O  OE1   . GLN B 1 83  ? 382.628 346.274 244.375 1.00 121.38 ? 83  GLN E OE1   1 
ATOM   3969  N  NE2   . GLN B 1 83  ? 381.749 347.098 246.269 1.00 126.67 ? 83  GLN E NE2   1 
ATOM   3970  N  N     . ILE B 1 84  ? 385.534 351.411 244.019 1.00 93.92  ? 84  ILE E N     1 
ATOM   3971  C  CA    . ILE B 1 84  ? 385.960 351.492 242.625 1.00 94.86  ? 84  ILE E CA    1 
ATOM   3972  C  C     . ILE B 1 84  ? 387.481 351.597 242.510 1.00 95.51  ? 84  ILE E C     1 
ATOM   3973  O  O     . ILE B 1 84  ? 388.060 351.150 241.514 1.00 102.84 ? 84  ILE E O     1 
ATOM   3974  C  CB    . ILE B 1 84  ? 385.239 352.656 241.916 1.00 91.81  ? 84  ILE E CB    1 
ATOM   3975  C  CG1   . ILE B 1 84  ? 385.149 352.366 240.411 1.00 97.28  ? 84  ILE E CG1   1 
ATOM   3976  C  CG2   . ILE B 1 84  ? 385.941 353.996 242.157 1.00 84.70  ? 84  ILE E CG2   1 
ATOM   3977  C  CD1   . ILE B 1 84  ? 384.701 353.536 239.553 1.00 97.05  ? 84  ILE E CD1   1 
ATOM   3978  N  N     . PHE B 1 85  ? 388.149 352.186 243.502 1.00 89.48  ? 85  PHE E N     1 
ATOM   3979  C  CA    . PHE B 1 85  ? 389.591 352.386 243.447 1.00 93.94  ? 85  PHE E CA    1 
ATOM   3980  C  C     . PHE B 1 85  ? 390.342 351.098 243.782 1.00 98.72  ? 85  PHE E C     1 
ATOM   3981  O  O     . PHE B 1 85  ? 389.821 350.192 244.436 1.00 98.23  ? 85  PHE E O     1 
ATOM   3982  C  CB    . PHE B 1 85  ? 390.019 353.493 244.414 1.00 92.76  ? 85  PHE E CB    1 
ATOM   3983  C  CG    . PHE B 1 85  ? 389.458 354.843 244.080 1.00 89.48  ? 85  PHE E CG    1 
ATOM   3984  C  CD1   . PHE B 1 85  ? 389.949 355.567 243.011 1.00 91.62  ? 85  PHE E CD1   1 
ATOM   3985  C  CD2   . PHE B 1 85  ? 388.440 355.390 244.841 1.00 90.89  ? 85  PHE E CD2   1 
ATOM   3986  C  CE1   . PHE B 1 85  ? 389.434 356.809 242.703 1.00 90.45  ? 85  PHE E CE1   1 
ATOM   3987  C  CE2   . PHE B 1 85  ? 387.922 356.632 244.536 1.00 84.57  ? 85  PHE E CE2   1 
ATOM   3988  C  CZ    . PHE B 1 85  ? 388.419 357.341 243.467 1.00 82.40  ? 85  PHE E CZ    1 
ATOM   3989  N  N     . ARG B 1 86  ? 391.588 351.029 243.315 1.00 106.17 ? 86  ARG E N     1 
ATOM   3990  C  CA    . ARG B 1 86  ? 392.473 349.946 243.719 1.00 104.59 ? 86  ARG E CA    1 
ATOM   3991  C  C     . ARG B 1 86  ? 392.916 350.158 245.172 1.00 104.44 ? 86  ARG E C     1 
ATOM   3992  O  O     . ARG B 1 86  ? 393.297 351.274 245.535 1.00 111.12 ? 86  ARG E O     1 
ATOM   3993  C  CB    . ARG B 1 86  ? 393.697 349.874 242.798 1.00 108.17 ? 86  ARG E CB    1 
ATOM   3994  C  CG    . ARG B 1 86  ? 394.659 348.728 243.132 1.00 109.30 ? 86  ARG E CG    1 
ATOM   3995  C  CD    . ARG B 1 86  ? 395.737 348.471 242.085 1.00 106.83 ? 86  ARG E CD    1 
ATOM   3996  N  NE    . ARG B 1 86  ? 395.216 347.947 240.823 1.00 111.08 ? 86  ARG E NE    1 
ATOM   3997  C  CZ    . ARG B 1 86  ? 395.077 348.613 239.681 1.00 112.47 ? 86  ARG E CZ    1 
ATOM   3998  N  NH1   . ARG B 1 86  ? 395.266 349.922 239.598 1.00 111.11 ? 86  ARG E NH1   1 
ATOM   3999  N  NH2   . ARG B 1 86  ? 394.727 347.944 238.586 1.00 109.83 ? 86  ARG E NH2   1 
ATOM   4000  N  N     . PRO B 1 87  ? 392.863 349.125 246.035 1.00 94.36  ? 87  PRO E N     1 
ATOM   4001  C  CA    . PRO B 1 87  ? 393.339 349.332 247.418 1.00 97.70  ? 87  PRO E CA    1 
ATOM   4002  C  C     . PRO B 1 87  ? 394.810 349.695 247.527 1.00 99.22  ? 87  PRO E C     1 
ATOM   4003  O  O     . PRO B 1 87  ? 395.187 350.429 248.447 1.00 102.09 ? 87  PRO E O     1 
ATOM   4004  C  CB    . PRO B 1 87  ? 393.048 347.987 248.097 1.00 99.72  ? 87  PRO E CB    1 
ATOM   4005  C  CG    . PRO B 1 87  ? 392.004 347.367 247.287 1.00 99.30  ? 87  PRO E CG    1 
ATOM   4006  C  CD    . PRO B 1 87  ? 392.303 347.767 245.888 1.00 97.58  ? 87  PRO E CD    1 
ATOM   4007  N  N     . ASP B 1 88  ? 395.655 349.178 246.633 1.00 117.59 ? 88  ASP E N     1 
ATOM   4008  C  CA    . ASP B 1 88  ? 397.081 349.492 246.670 1.00 122.02 ? 88  ASP E CA    1 
ATOM   4009  C  C     . ASP B 1 88  ? 397.336 350.983 246.467 1.00 120.83 ? 88  ASP E C     1 
ATOM   4010  O  O     . ASP B 1 88  ? 398.282 351.532 247.042 1.00 121.63 ? 88  ASP E O     1 
ATOM   4011  C  CB    . ASP B 1 88  ? 397.807 348.666 245.604 1.00 126.66 ? 88  ASP E CB    1 
ATOM   4012  C  CG    . ASP B 1 88  ? 399.313 348.580 245.831 1.00 130.44 ? 88  ASP E CG    1 
ATOM   4013  O  OD1   . ASP B 1 88  ? 399.899 347.549 245.443 1.00 130.11 ? 88  ASP E OD1   1 
ATOM   4014  O  OD2   . ASP B 1 88  ? 399.917 349.517 246.392 1.00 130.49 ? 88  ASP E OD2   1 
ATOM   4015  N  N     . ASN B 1 89  ? 396.505 351.659 245.671 1.00 112.34 ? 89  ASN E N     1 
ATOM   4016  C  CA    . ASN B 1 89  ? 396.703 353.084 245.434 1.00 107.85 ? 89  ASN E CA    1 
ATOM   4017  C  C     . ASN B 1 89  ? 396.413 353.944 246.661 1.00 107.98 ? 89  ASN E C     1 
ATOM   4018  O  O     . ASN B 1 89  ? 396.802 355.116 246.677 1.00 108.35 ? 89  ASN E O     1 
ATOM   4019  C  CB    . ASN B 1 89  ? 395.831 353.542 244.266 1.00 112.16 ? 89  ASN E CB    1 
ATOM   4020  C  CG    . ASN B 1 89  ? 396.324 353.019 242.931 1.00 112.64 ? 89  ASN E CG    1 
ATOM   4021  O  OD1   . ASN B 1 89  ? 397.292 352.262 242.865 1.00 108.67 ? 89  ASN E OD1   1 
ATOM   4022  N  ND2   . ASN B 1 89  ? 395.654 353.417 241.857 1.00 117.31 ? 89  ASN E ND2   1 
ATOM   4023  N  N     . PHE B 1 90  ? 395.750 353.404 247.686 1.00 105.66 ? 90  PHE E N     1 
ATOM   4024  C  CA    . PHE B 1 90  ? 395.514 354.129 248.937 1.00 100.06 ? 90  PHE E CA    1 
ATOM   4025  C  C     . PHE B 1 90  ? 396.822 354.211 249.720 1.00 108.44 ? 90  PHE E C     1 
ATOM   4026  O  O     . PHE B 1 90  ? 397.031 353.520 250.720 1.00 117.45 ? 90  PHE E O     1 
ATOM   4027  C  CB    . PHE B 1 90  ? 394.434 353.441 249.762 1.00 106.74 ? 90  PHE E CB    1 
ATOM   4028  C  CG    . PHE B 1 90  ? 393.043 353.596 249.218 1.00 109.15 ? 90  PHE E CG    1 
ATOM   4029  C  CD1   . PHE B 1 90  ? 392.610 352.833 248.152 1.00 113.11 ? 90  PHE E CD1   1 
ATOM   4030  C  CD2   . PHE B 1 90  ? 392.145 354.458 249.825 1.00 110.34 ? 90  PHE E CD2   1 
ATOM   4031  C  CE1   . PHE B 1 90  ? 391.326 352.961 247.668 1.00 112.38 ? 90  PHE E CE1   1 
ATOM   4032  C  CE2   . PHE B 1 90  ? 390.853 354.584 249.350 1.00 109.35 ? 90  PHE E CE2   1 
ATOM   4033  C  CZ    . PHE B 1 90  ? 390.446 353.835 248.267 1.00 109.37 ? 90  PHE E CZ    1 
ATOM   4034  N  N     . VAL B 1 91  ? 397.710 355.088 249.256 1.00 104.12 ? 91  VAL E N     1 
ATOM   4035  C  CA    . VAL B 1 91  ? 398.974 355.362 249.935 1.00 104.35 ? 91  VAL E CA    1 
ATOM   4036  C  C     . VAL B 1 91  ? 398.741 356.502 250.915 1.00 105.10 ? 91  VAL E C     1 
ATOM   4037  O  O     . VAL B 1 91  ? 398.126 357.515 250.566 1.00 108.32 ? 91  VAL E O     1 
ATOM   4038  C  CB    . VAL B 1 91  ? 400.096 355.702 248.935 1.00 105.78 ? 91  VAL E CB    1 
ATOM   4039  C  CG1   . VAL B 1 91  ? 399.823 357.009 248.160 1.00 109.80 ? 91  VAL E CG1   1 
ATOM   4040  C  CG2   . VAL B 1 91  ? 401.448 355.766 249.655 1.00 102.39 ? 91  VAL E CG2   1 
ATOM   4041  N  N     . PHE B 1 92  ? 399.190 356.323 252.154 1.00 123.47 ? 92  PHE E N     1 
ATOM   4042  C  CA    . PHE B 1 92  ? 398.882 357.266 253.220 1.00 126.73 ? 92  PHE E CA    1 
ATOM   4043  C  C     . PHE B 1 92  ? 399.912 357.142 254.335 1.00 126.26 ? 92  PHE E C     1 
ATOM   4044  O  O     . PHE B 1 92  ? 400.377 356.041 254.642 1.00 125.24 ? 92  PHE E O     1 
ATOM   4045  C  CB    . PHE B 1 92  ? 397.444 357.034 253.721 1.00 123.37 ? 92  PHE E CB    1 
ATOM   4046  C  CG    . PHE B 1 92  ? 397.347 356.200 254.960 1.00 127.08 ? 92  PHE E CG    1 
ATOM   4047  C  CD1   . PHE B 1 92  ? 397.324 354.819 254.868 1.00 126.53 ? 92  PHE E CD1   1 
ATOM   4048  C  CD2   . PHE B 1 92  ? 397.207 356.782 256.204 1.00 129.47 ? 92  PHE E CD2   1 
ATOM   4049  C  CE1   . PHE B 1 92  ? 397.222 354.038 255.998 1.00 128.86 ? 92  PHE E CE1   1 
ATOM   4050  C  CE2   . PHE B 1 92  ? 397.109 356.008 257.330 1.00 128.52 ? 92  PHE E CE2   1 
ATOM   4051  C  CZ    . PHE B 1 92  ? 397.109 354.636 257.231 1.00 128.04 ? 92  PHE E CZ    1 
ATOM   4052  N  N     . GLY B 1 93  ? 400.272 358.284 254.919 1.00 118.48 ? 93  GLY E N     1 
ATOM   4053  C  CA    . GLY B 1 93  ? 401.265 358.342 255.972 1.00 117.30 ? 93  GLY E CA    1 
ATOM   4054  C  C     . GLY B 1 93  ? 400.662 358.216 257.360 1.00 118.11 ? 93  GLY E C     1 
ATOM   4055  O  O     . GLY B 1 93  ? 399.448 358.263 257.560 1.00 120.01 ? 93  GLY E O     1 
ATOM   4056  N  N     . GLN B 1 94  ? 401.554 358.107 258.348 1.00 122.33 ? 94  GLN E N     1 
ATOM   4057  C  CA    . GLN B 1 94  ? 401.169 357.764 259.712 1.00 120.65 ? 94  GLN E CA    1 
ATOM   4058  C  C     . GLN B 1 94  ? 400.836 358.966 260.587 1.00 116.45 ? 94  GLN E C     1 
ATOM   4059  O  O     . GLN B 1 94  ? 400.240 358.778 261.653 1.00 115.28 ? 94  GLN E O     1 
ATOM   4060  C  CB    . GLN B 1 94  ? 402.299 356.964 260.391 1.00 121.73 ? 94  GLN E CB    1 
ATOM   4061  C  CG    . GLN B 1 94  ? 401.913 355.974 261.524 1.00 126.21 ? 94  GLN E CG    1 
ATOM   4062  C  CD    . GLN B 1 94  ? 400.769 355.027 261.188 1.00 124.64 ? 94  GLN E CD    1 
ATOM   4063  O  OE1   . GLN B 1 94  ? 400.757 354.404 260.127 1.00 121.81 ? 94  GLN E OE1   1 
ATOM   4064  N  NE2   . GLN B 1 94  ? 399.800 354.921 262.090 1.00 123.62 ? 94  GLN E NE2   1 
ATOM   4065  N  N     . SER B 1 95  ? 401.199 360.180 260.176 1.00 115.60 ? 95  SER E N     1 
ATOM   4066  C  CA    . SER B 1 95  ? 400.898 361.377 260.949 1.00 115.68 ? 95  SER E CA    1 
ATOM   4067  C  C     . SER B 1 95  ? 400.670 362.535 259.994 1.00 114.66 ? 95  SER E C     1 
ATOM   4068  O  O     . SER B 1 95  ? 401.355 362.662 258.976 1.00 118.78 ? 95  SER E O     1 
ATOM   4069  C  CB    . SER B 1 95  ? 402.024 361.715 261.932 1.00 119.96 ? 95  SER E CB    1 
ATOM   4070  O  OG    . SER B 1 95  ? 401.884 360.982 263.135 1.00 125.74 ? 95  SER E OG    1 
ATOM   4071  N  N     . GLY B 1 96  ? 399.708 363.381 260.338 1.00 106.67 ? 96  GLY E N     1 
ATOM   4072  C  CA    . GLY B 1 96  ? 399.352 364.488 259.481 1.00 110.40 ? 96  GLY E CA    1 
ATOM   4073  C  C     . GLY B 1 96  ? 400.440 365.540 259.418 1.00 109.11 ? 96  GLY E C     1 
ATOM   4074  O  O     . GLY B 1 96  ? 401.363 365.590 260.231 1.00 102.94 ? 96  GLY E O     1 
ATOM   4075  N  N     . ALA B 1 97  ? 400.317 366.402 258.412 1.00 108.99 ? 97  ALA E N     1 
ATOM   4076  C  CA    . ALA B 1 97  ? 401.242 367.505 258.199 1.00 105.27 ? 97  ALA E CA    1 
ATOM   4077  C  C     . ALA B 1 97  ? 400.876 368.747 258.999 1.00 106.91 ? 97  ALA E C     1 
ATOM   4078  O  O     . ALA B 1 97  ? 401.564 369.766 258.878 1.00 105.77 ? 97  ALA E O     1 
ATOM   4079  C  CB    . ALA B 1 97  ? 401.296 367.866 256.714 1.00 109.28 ? 97  ALA E CB    1 
ATOM   4080  N  N     . GLY B 1 98  ? 399.834 368.685 259.824 1.00 103.95 ? 98  GLY E N     1 
ATOM   4081  C  CA    . GLY B 1 98  ? 399.276 369.908 260.368 1.00 99.58  ? 98  GLY E CA    1 
ATOM   4082  C  C     . GLY B 1 98  ? 398.790 370.780 259.231 1.00 103.12 ? 98  GLY E C     1 
ATOM   4083  O  O     . GLY B 1 98  ? 398.092 370.319 258.320 1.00 111.30 ? 98  GLY E O     1 
ATOM   4084  N  N     . ASN B 1 99  ? 399.150 372.059 259.288 1.00 90.58  ? 99  ASN E N     1 
ATOM   4085  C  CA    . ASN B 1 99  ? 399.011 372.991 258.175 1.00 96.72  ? 99  ASN E CA    1 
ATOM   4086  C  C     . ASN B 1 99  ? 400.371 373.599 257.863 1.00 95.02  ? 99  ASN E C     1 
ATOM   4087  O  O     . ASN B 1 99  ? 400.495 374.784 257.542 1.00 104.05 ? 99  ASN E O     1 
ATOM   4088  C  CB    . ASN B 1 99  ? 397.964 374.063 258.483 1.00 99.91  ? 99  ASN E CB    1 
ATOM   4089  C  CG    . ASN B 1 99  ? 396.535 373.539 258.391 1.00 98.45  ? 99  ASN E CG    1 
ATOM   4090  O  OD1   . ASN B 1 99  ? 395.778 373.618 259.355 1.00 94.83  ? 99  ASN E OD1   1 
ATOM   4091  N  ND2   . ASN B 1 99  ? 396.157 373.021 257.226 1.00 102.36 ? 99  ASN E ND2   1 
ATOM   4092  N  N     . ASN B 1 100 ? 401.410 372.768 257.938 1.00 88.96  ? 100 ASN E N     1 
ATOM   4093  C  CA    . ASN B 1 100 ? 402.802 373.188 257.833 1.00 94.30  ? 100 ASN E CA    1 
ATOM   4094  C  C     . ASN B 1 100 ? 403.356 372.719 256.494 1.00 95.54  ? 100 ASN E C     1 
ATOM   4095  O  O     . ASN B 1 100 ? 403.455 371.510 256.243 1.00 102.86 ? 100 ASN E O     1 
ATOM   4096  C  CB    . ASN B 1 100 ? 403.613 372.615 258.996 1.00 94.21  ? 100 ASN E CB    1 
ATOM   4097  C  CG    . ASN B 1 100 ? 405.004 373.217 259.109 1.00 97.47  ? 100 ASN E CG    1 
ATOM   4098  O  OD1   . ASN B 1 100 ? 405.521 373.823 258.173 1.00 98.79  ? 100 ASN E OD1   1 
ATOM   4099  N  ND2   . ASN B 1 100 ? 405.618 373.048 260.272 1.00 99.24  ? 100 ASN E ND2   1 
ATOM   4100  N  N     . TRP B 1 101 ? 403.730 373.682 255.647 1.00 100.12 ? 101 TRP E N     1 
ATOM   4101  C  CA    . TRP B 1 101 ? 404.342 373.350 254.367 1.00 101.02 ? 101 TRP E CA    1 
ATOM   4102  C  C     . TRP B 1 101 ? 405.655 372.612 254.572 1.00 105.36 ? 101 TRP E C     1 
ATOM   4103  O  O     . TRP B 1 101 ? 405.980 371.690 253.818 1.00 110.35 ? 101 TRP E O     1 
ATOM   4104  C  CB    . TRP B 1 101 ? 404.572 374.619 253.546 1.00 104.20 ? 101 TRP E CB    1 
ATOM   4105  C  CG    . TRP B 1 101 ? 405.009 374.354 252.138 1.00 104.86 ? 101 TRP E CG    1 
ATOM   4106  C  CD1   . TRP B 1 101 ? 404.205 374.265 251.045 1.00 108.99 ? 101 TRP E CD1   1 
ATOM   4107  C  CD2   . TRP B 1 101 ? 406.347 374.144 251.668 1.00 102.29 ? 101 TRP E CD2   1 
ATOM   4108  N  NE1   . TRP B 1 101 ? 404.951 374.011 249.923 1.00 107.00 ? 101 TRP E NE1   1 
ATOM   4109  C  CE2   . TRP B 1 101 ? 406.271 373.931 250.278 1.00 106.09 ? 101 TRP E CE2   1 
ATOM   4110  C  CE3   . TRP B 1 101 ? 407.600 374.111 252.285 1.00 104.40 ? 101 TRP E CE3   1 
ATOM   4111  C  CZ2   . TRP B 1 101 ? 407.396 373.692 249.497 1.00 105.79 ? 101 TRP E CZ2   1 
ATOM   4112  C  CZ3   . TRP B 1 101 ? 408.716 373.873 251.507 1.00 108.69 ? 101 TRP E CZ3   1 
ATOM   4113  C  CH2   . TRP B 1 101 ? 408.607 373.668 250.128 1.00 108.19 ? 101 TRP E CH2   1 
ATOM   4114  N  N     . ALA B 1 102 ? 406.429 373.015 255.582 1.00 99.37  ? 102 ALA E N     1 
ATOM   4115  C  CA    . ALA B 1 102 ? 407.697 372.352 255.859 1.00 99.07  ? 102 ALA E CA    1 
ATOM   4116  C  C     . ALA B 1 102 ? 407.486 370.899 256.256 1.00 101.62 ? 102 ALA E C     1 
ATOM   4117  O  O     . ALA B 1 102 ? 408.216 370.011 255.800 1.00 101.33 ? 102 ALA E O     1 
ATOM   4118  C  CB    . ALA B 1 102 ? 408.442 373.098 256.961 1.00 100.65 ? 102 ALA E CB    1 
ATOM   4119  N  N     . LYS B 1 103 ? 406.493 370.637 257.107 1.00 101.42 ? 103 LYS E N     1 
ATOM   4120  C  CA    . LYS B 1 103 ? 406.202 369.267 257.515 1.00 98.35  ? 103 LYS E CA    1 
ATOM   4121  C  C     . LYS B 1 103 ? 405.739 368.437 256.327 1.00 98.20  ? 103 LYS E C     1 
ATOM   4122  O  O     . LYS B 1 103 ? 406.162 367.289 256.148 1.00 97.28  ? 103 LYS E O     1 
ATOM   4123  C  CB    . LYS B 1 103 ? 405.141 369.267 258.615 1.00 95.32  ? 103 LYS E CB    1 
ATOM   4124  C  CG    . LYS B 1 103 ? 405.035 367.946 259.381 1.00 99.18  ? 103 LYS E CG    1 
ATOM   4125  C  CD    . LYS B 1 103 ? 404.159 368.014 260.644 1.00 98.96  ? 103 LYS E CD    1 
ATOM   4126  C  CE    . LYS B 1 103 ? 404.713 368.879 261.779 1.00 99.86  ? 103 LYS E CE    1 
ATOM   4127  N  NZ    . LYS B 1 103 ? 405.432 368.056 262.786 1.00 104.70 ? 103 LYS E NZ    1 
ATOM   4128  N  N     . GLY B 1 104 ? 404.860 369.006 255.499 1.00 118.49 ? 104 GLY E N     1 
ATOM   4129  C  CA    . GLY B 1 104 ? 404.386 368.280 254.333 1.00 118.24 ? 104 GLY E CA    1 
ATOM   4130  C  C     . GLY B 1 104 ? 405.473 368.003 253.313 1.00 116.93 ? 104 GLY E C     1 
ATOM   4131  O  O     . GLY B 1 104 ? 405.478 366.945 252.679 1.00 119.42 ? 104 GLY E O     1 
ATOM   4132  N  N     . HIS B 1 105 ? 406.407 368.938 253.147 1.00 113.02 ? 105 HIS E N     1 
ATOM   4133  C  CA    . HIS B 1 105 ? 407.404 368.831 252.088 1.00 112.15 ? 105 HIS E CA    1 
ATOM   4134  C  C     . HIS B 1 105 ? 408.586 367.975 252.528 1.00 108.96 ? 105 HIS E C     1 
ATOM   4135  O  O     . HIS B 1 105 ? 408.944 366.998 251.862 1.00 110.29 ? 105 HIS E O     1 
ATOM   4136  C  CB    . HIS B 1 105 ? 407.868 370.233 251.690 1.00 108.43 ? 105 HIS E CB    1 
ATOM   4137  C  CG    . HIS B 1 105 ? 408.749 370.265 250.482 1.00 109.30 ? 105 HIS E CG    1 
ATOM   4138  N  ND1   . HIS B 1 105 ? 408.266 370.544 249.222 1.00 109.35 ? 105 HIS E ND1   1 
ATOM   4139  C  CD2   . HIS B 1 105 ? 410.083 370.084 250.341 1.00 106.61 ? 105 HIS E CD2   1 
ATOM   4140  C  CE1   . HIS B 1 105 ? 409.262 370.518 248.355 1.00 107.09 ? 105 HIS E CE1   1 
ATOM   4141  N  NE2   . HIS B 1 105 ? 410.375 370.241 249.008 1.00 110.50 ? 105 HIS E NE2   1 
ATOM   4142  N  N     . TYR B 1 106 ? 409.206 368.334 253.654 1.00 102.03 ? 106 TYR E N     1 
ATOM   4143  C  CA    . TYR B 1 106 ? 410.461 367.712 254.063 1.00 102.31 ? 106 TYR E CA    1 
ATOM   4144  C  C     . TYR B 1 106 ? 410.236 366.488 254.944 1.00 104.99 ? 106 TYR E C     1 
ATOM   4145  O  O     . TYR B 1 106 ? 410.677 365.383 254.612 1.00 110.46 ? 106 TYR E O     1 
ATOM   4146  C  CB    . TYR B 1 106 ? 411.325 368.736 254.798 1.00 97.49  ? 106 TYR E CB    1 
ATOM   4147  C  CG    . TYR B 1 106 ? 411.794 369.868 253.921 1.00 100.18 ? 106 TYR E CG    1 
ATOM   4148  C  CD1   . TYR B 1 106 ? 412.836 369.693 253.021 1.00 102.41 ? 106 TYR E CD1   1 
ATOM   4149  C  CD2   . TYR B 1 106 ? 411.187 371.111 253.986 1.00 103.29 ? 106 TYR E CD2   1 
ATOM   4150  C  CE1   . TYR B 1 106 ? 413.263 370.728 252.217 1.00 104.33 ? 106 TYR E CE1   1 
ATOM   4151  C  CE2   . TYR B 1 106 ? 411.607 372.150 253.186 1.00 105.04 ? 106 TYR E CE2   1 
ATOM   4152  C  CZ    . TYR B 1 106 ? 412.644 371.955 252.303 1.00 103.34 ? 106 TYR E CZ    1 
ATOM   4153  O  OH    . TYR B 1 106 ? 413.066 372.989 251.502 1.00 101.12 ? 106 TYR E OH    1 
ATOM   4154  N  N     . THR B 1 107 ? 409.551 366.666 256.075 1.00 102.90 ? 107 THR E N     1 
ATOM   4155  C  CA    . THR B 1 107 ? 409.639 365.684 257.152 1.00 103.57 ? 107 THR E CA    1 
ATOM   4156  C  C     . THR B 1 107 ? 408.883 364.396 256.817 1.00 110.20 ? 107 THR E C     1 
ATOM   4157  O  O     . THR B 1 107 ? 409.473 363.309 256.820 1.00 117.08 ? 107 THR E O     1 
ATOM   4158  C  CB    . THR B 1 107 ? 409.159 366.310 258.464 1.00 111.61 ? 107 THR E CB    1 
ATOM   4159  O  OG1   . THR B 1 107 ? 409.745 367.608 258.614 1.00 114.12 ? 107 THR E OG1   1 
ATOM   4160  C  CG2   . THR B 1 107 ? 409.548 365.441 259.667 1.00 113.36 ? 107 THR E CG2   1 
ATOM   4161  N  N     . GLU B 1 108 ? 407.575 364.485 256.532 1.00 110.79 ? 108 GLU E N     1 
ATOM   4162  C  CA    . GLU B 1 108 ? 406.844 363.309 256.037 1.00 113.25 ? 108 GLU E CA    1 
ATOM   4163  C  C     . GLU B 1 108 ? 407.055 363.061 254.547 1.00 116.13 ? 108 GLU E C     1 
ATOM   4164  O  O     . GLU B 1 108 ? 406.893 361.919 254.088 1.00 122.45 ? 108 GLU E O     1 
ATOM   4165  C  CB    . GLU B 1 108 ? 405.326 363.410 256.276 1.00 114.62 ? 108 GLU E CB    1 
ATOM   4166  C  CG    . GLU B 1 108 ? 404.742 363.339 257.708 1.00 116.21 ? 108 GLU E CG    1 
ATOM   4167  C  CD    . GLU B 1 108 ? 405.428 364.190 258.737 1.00 117.67 ? 108 GLU E CD    1 
ATOM   4168  O  OE1   . GLU B 1 108 ? 406.170 365.100 258.341 1.00 118.46 ? 108 GLU E OE1   1 
ATOM   4169  O  OE2   . GLU B 1 108 ? 405.223 363.942 259.943 1.00 119.71 ? 108 GLU E OE2   1 
ATOM   4170  N  N     . GLY B 1 109 ? 407.374 364.107 253.780 1.00 104.11 ? 109 GLY E N     1 
ATOM   4171  C  CA    . GLY B 1 109 ? 407.493 363.950 252.341 1.00 103.69 ? 109 GLY E CA    1 
ATOM   4172  C  C     . GLY B 1 109 ? 408.596 362.988 251.955 1.00 109.91 ? 109 GLY E C     1 
ATOM   4173  O  O     . GLY B 1 109 ? 408.407 362.127 251.092 1.00 118.24 ? 109 GLY E O     1 
ATOM   4174  N  N     . ALA B 1 110 ? 409.742 363.084 252.631 1.00 111.95 ? 110 ALA E N     1 
ATOM   4175  C  CA    . ALA B 1 110 ? 410.844 362.169 252.357 1.00 119.57 ? 110 ALA E CA    1 
ATOM   4176  C  C     . ALA B 1 110 ? 410.465 360.722 252.650 1.00 122.22 ? 110 ALA E C     1 
ATOM   4177  O  O     . ALA B 1 110 ? 410.981 359.803 252.003 1.00 121.97 ? 110 ALA E O     1 
ATOM   4178  C  CB    . ALA B 1 110 ? 412.073 362.575 253.168 1.00 119.89 ? 110 ALA E CB    1 
ATOM   4179  N  N     . GLU B 1 111 ? 409.552 360.500 253.596 1.00 120.44 ? 111 GLU E N     1 
ATOM   4180  C  CA    . GLU B 1 111 ? 409.075 359.149 253.874 1.00 121.90 ? 111 GLU E CA    1 
ATOM   4181  C  C     . GLU B 1 111 ? 408.142 358.646 252.777 1.00 122.14 ? 111 GLU E C     1 
ATOM   4182  O  O     . GLU B 1 111 ? 408.403 357.605 252.167 1.00 123.93 ? 111 GLU E O     1 
ATOM   4183  C  CB    . GLU B 1 111 ? 408.369 359.101 255.235 1.00 121.44 ? 111 GLU E CB    1 
ATOM   4184  C  CG    . GLU B 1 111 ? 409.274 359.029 256.491 1.00 125.05 ? 111 GLU E CG    1 
ATOM   4185  C  CD    . GLU B 1 111 ? 410.418 360.032 256.526 1.00 122.94 ? 111 GLU E CD    1 
ATOM   4186  O  OE1   . GLU B 1 111 ? 411.346 359.835 257.336 1.00 121.49 ? 111 GLU E OE1   1 
ATOM   4187  O  OE2   . GLU B 1 111 ? 410.391 361.015 255.758 1.00 121.89 ? 111 GLU E OE2   1 
ATOM   4188  N  N     . LEU B 1 112 ? 407.054 359.375 252.499 1.00 118.59 ? 112 LEU E N     1 
ATOM   4189  C  CA    . LEU B 1 112 ? 405.989 358.815 251.664 1.00 119.98 ? 112 LEU E CA    1 
ATOM   4190  C  C     . LEU B 1 112 ? 406.222 358.971 250.161 1.00 118.59 ? 112 LEU E C     1 
ATOM   4191  O  O     . LEU B 1 112 ? 405.575 358.250 249.376 1.00 120.76 ? 112 LEU E O     1 
ATOM   4192  C  CB    . LEU B 1 112 ? 404.641 359.451 252.012 1.00 118.46 ? 112 LEU E CB    1 
ATOM   4193  C  CG    . LEU B 1 112 ? 403.808 358.829 253.137 1.00 123.57 ? 112 LEU E CG    1 
ATOM   4194  C  CD1   . LEU B 1 112 ? 403.027 357.633 252.624 1.00 122.40 ? 112 LEU E CD1   1 
ATOM   4195  C  CD2   . LEU B 1 112 ? 404.659 358.450 254.339 1.00 119.70 ? 112 LEU E CD2   1 
ATOM   4196  N  N     . VAL B 1 113 ? 407.111 359.879 249.736 1.00 108.56 ? 113 VAL E N     1 
ATOM   4197  C  CA    . VAL B 1 113 ? 407.227 360.166 248.310 1.00 112.10 ? 113 VAL E CA    1 
ATOM   4198  C  C     . VAL B 1 113 ? 407.778 358.969 247.541 1.00 116.02 ? 113 VAL E C     1 
ATOM   4199  O  O     . VAL B 1 113 ? 407.471 358.795 246.358 1.00 120.50 ? 113 VAL E O     1 
ATOM   4200  C  CB    . VAL B 1 113 ? 408.077 361.429 248.090 1.00 108.71 ? 113 VAL E CB    1 
ATOM   4201  C  CG1   . VAL B 1 113 ? 409.549 361.186 248.454 1.00 112.03 ? 113 VAL E CG1   1 
ATOM   4202  C  CG2   . VAL B 1 113 ? 407.939 361.931 246.655 1.00 109.84 ? 113 VAL E CG2   1 
ATOM   4203  N  N     . ASP B 1 114 ? 408.575 358.117 248.192 1.00 132.10 ? 114 ASP E N     1 
ATOM   4204  C  CA    . ASP B 1 114 ? 409.052 356.904 247.537 1.00 137.32 ? 114 ASP E CA    1 
ATOM   4205  C  C     . ASP B 1 114 ? 407.888 355.995 247.154 1.00 137.88 ? 114 ASP E C     1 
ATOM   4206  O  O     . ASP B 1 114 ? 407.789 355.540 246.006 1.00 140.14 ? 114 ASP E O     1 
ATOM   4207  C  CB    . ASP B 1 114 ? 410.026 356.163 248.452 1.00 139.17 ? 114 ASP E CB    1 
ATOM   4208  C  CG    . ASP B 1 114 ? 411.285 356.958 248.733 1.00 138.15 ? 114 ASP E CG    1 
ATOM   4209  O  OD1   . ASP B 1 114 ? 411.523 357.965 248.033 1.00 136.63 ? 114 ASP E OD1   1 
ATOM   4210  O  OD2   . ASP B 1 114 ? 412.038 356.576 249.652 1.00 137.31 ? 114 ASP E OD2   1 
ATOM   4211  N  N     . SER B 1 115 ? 406.984 355.735 248.104 1.00 134.71 ? 115 SER E N     1 
ATOM   4212  C  CA    . SER B 1 115 ? 405.867 354.838 247.827 1.00 137.65 ? 115 SER E CA    1 
ATOM   4213  C  C     . SER B 1 115 ? 404.931 355.429 246.781 1.00 138.30 ? 115 SER E C     1 
ATOM   4214  O  O     . SER B 1 115 ? 404.480 354.717 245.866 1.00 143.67 ? 115 SER E O     1 
ATOM   4215  C  CB    . SER B 1 115 ? 405.105 354.528 249.112 1.00 140.10 ? 115 SER E CB    1 
ATOM   4216  O  OG    . SER B 1 115 ? 404.096 353.562 248.878 1.00 144.58 ? 115 SER E OG    1 
ATOM   4217  N  N     . VAL B 1 116 ? 404.637 356.731 246.883 1.00 120.17 ? 116 VAL E N     1 
ATOM   4218  C  CA    . VAL B 1 116 ? 403.725 357.315 245.898 1.00 123.92 ? 116 VAL E CA    1 
ATOM   4219  C  C     . VAL B 1 116 ? 404.367 357.328 244.514 1.00 124.27 ? 116 VAL E C     1 
ATOM   4220  O  O     . VAL B 1 116 ? 403.675 357.175 243.504 1.00 125.48 ? 116 VAL E O     1 
ATOM   4221  C  CB    . VAL B 1 116 ? 403.215 358.712 246.320 1.00 122.65 ? 116 VAL E CB    1 
ATOM   4222  C  CG1   . VAL B 1 116 ? 402.813 358.760 247.794 1.00 128.50 ? 116 VAL E CG1   1 
ATOM   4223  C  CG2   . VAL B 1 116 ? 404.243 359.787 246.031 1.00 120.81 ? 116 VAL E CG2   1 
ATOM   4224  N  N     . LEU B 1 117 ? 405.693 357.502 244.434 1.00 120.18 ? 117 LEU E N     1 
ATOM   4225  C  CA    . LEU B 1 117 ? 406.334 357.471 243.125 1.00 121.12 ? 117 LEU E CA    1 
ATOM   4226  C  C     . LEU B 1 117 ? 406.386 356.064 242.547 1.00 124.14 ? 117 LEU E C     1 
ATOM   4227  O  O     . LEU B 1 117 ? 406.321 355.910 241.327 1.00 122.45 ? 117 LEU E O     1 
ATOM   4228  C  CB    . LEU B 1 117 ? 407.737 358.069 243.198 1.00 118.86 ? 117 LEU E CB    1 
ATOM   4229  C  CG    . LEU B 1 117 ? 407.769 359.600 243.251 1.00 114.56 ? 117 LEU E CG    1 
ATOM   4230  C  CD1   . LEU B 1 117 ? 409.130 360.083 243.711 1.00 119.84 ? 117 LEU E CD1   1 
ATOM   4231  C  CD2   . LEU B 1 117 ? 407.404 360.237 241.906 1.00 113.54 ? 117 LEU E CD2   1 
ATOM   4232  N  N     . ASP B 1 118 ? 406.480 355.028 243.385 1.00 140.12 ? 118 ASP E N     1 
ATOM   4233  C  CA    . ASP B 1 118 ? 406.323 353.669 242.857 1.00 139.25 ? 118 ASP E CA    1 
ATOM   4234  C  C     . ASP B 1 118 ? 404.922 353.454 242.294 1.00 139.60 ? 118 ASP E C     1 
ATOM   4235  O  O     . ASP B 1 118 ? 404.757 352.833 241.236 1.00 140.15 ? 118 ASP E O     1 
ATOM   4236  C  CB    . ASP B 1 118 ? 406.650 352.612 243.916 1.00 137.36 ? 118 ASP E CB    1 
ATOM   4237  C  CG    . ASP B 1 118 ? 407.967 352.868 244.615 1.00 140.90 ? 118 ASP E CG    1 
ATOM   4238  O  OD1   . ASP B 1 118 ? 408.333 352.075 245.507 1.00 143.79 ? 118 ASP E OD1   1 
ATOM   4239  O  OD2   . ASP B 1 118 ? 408.673 353.811 244.209 1.00 139.81 ? 118 ASP E OD2   1 
ATOM   4240  N  N     . VAL B 1 119 ? 403.896 353.959 242.985 1.00 121.83 ? 119 VAL E N     1 
ATOM   4241  C  CA    . VAL B 1 119 ? 402.536 353.822 242.456 1.00 114.35 ? 119 VAL E CA    1 
ATOM   4242  C  C     . VAL B 1 119 ? 402.387 354.599 241.148 1.00 114.33 ? 119 VAL E C     1 
ATOM   4243  O  O     . VAL B 1 119 ? 401.786 354.106 240.179 1.00 119.53 ? 119 VAL E O     1 
ATOM   4244  C  CB    . VAL B 1 119 ? 401.493 354.265 243.501 1.00 111.15 ? 119 VAL E CB    1 
ATOM   4245  C  CG1   . VAL B 1 119 ? 400.079 354.197 242.916 1.00 113.65 ? 119 VAL E CG1   1 
ATOM   4246  C  CG2   . VAL B 1 119 ? 401.563 353.394 244.755 1.00 115.06 ? 119 VAL E CG2   1 
ATOM   4247  N  N     . VAL B 1 120 ? 402.934 355.816 241.099 1.00 110.68 ? 120 VAL E N     1 
ATOM   4248  C  CA    . VAL B 1 120 ? 402.879 356.630 239.888 1.00 114.14 ? 120 VAL E CA    1 
ATOM   4249  C  C     . VAL B 1 120 ? 403.600 355.926 238.748 1.00 118.08 ? 120 VAL E C     1 
ATOM   4250  O  O     . VAL B 1 120 ? 403.131 355.922 237.604 1.00 121.04 ? 120 VAL E O     1 
ATOM   4251  C  CB    . VAL B 1 120 ? 403.476 358.027 240.158 1.00 111.20 ? 120 VAL E CB    1 
ATOM   4252  C  CG1   . VAL B 1 120 ? 403.695 358.797 238.854 1.00 110.33 ? 120 VAL E CG1   1 
ATOM   4253  C  CG2   . VAL B 1 120 ? 402.583 358.844 241.092 1.00 114.87 ? 120 VAL E CG2   1 
ATOM   4254  N  N     . ARG B 1 121 ? 404.752 355.324 239.042 1.00 129.26 ? 121 ARG E N     1 
ATOM   4255  C  CA    . ARG B 1 121 ? 405.506 354.615 238.019 1.00 131.78 ? 121 ARG E CA    1 
ATOM   4256  C  C     . ARG B 1 121 ? 404.738 353.415 237.488 1.00 134.48 ? 121 ARG E C     1 
ATOM   4257  O  O     . ARG B 1 121 ? 404.731 353.172 236.276 1.00 135.51 ? 121 ARG E O     1 
ATOM   4258  C  CB    . ARG B 1 121 ? 406.854 354.172 238.581 1.00 134.49 ? 121 ARG E CB    1 
ATOM   4259  C  CG    . ARG B 1 121 ? 407.910 353.932 237.518 1.00 137.37 ? 121 ARG E CG    1 
ATOM   4260  C  CD    . ARG B 1 121 ? 409.276 353.678 238.131 1.00 138.25 ? 121 ARG E CD    1 
ATOM   4261  N  NE    . ARG B 1 121 ? 409.844 354.894 238.714 1.00 139.72 ? 121 ARG E NE    1 
ATOM   4262  C  CZ    . ARG B 1 121 ? 409.844 355.228 240.001 1.00 139.45 ? 121 ARG E CZ    1 
ATOM   4263  N  NH1   . ARG B 1 121 ? 409.242 354.489 240.924 1.00 140.52 ? 121 ARG E NH1   1 
ATOM   4264  N  NH2   . ARG B 1 121 ? 410.450 356.351 240.375 1.00 136.87 ? 121 ARG E NH2   1 
ATOM   4265  N  N     . LYS B 1 122 ? 404.098 352.640 238.372 1.00 130.55 ? 122 LYS E N     1 
ATOM   4266  C  CA    . LYS B 1 122 ? 403.390 351.457 237.890 1.00 131.90 ? 122 LYS E CA    1 
ATOM   4267  C  C     . LYS B 1 122 ? 402.200 351.865 237.028 1.00 130.79 ? 122 LYS E C     1 
ATOM   4268  O  O     . LYS B 1 122 ? 401.943 351.254 235.983 1.00 134.17 ? 122 LYS E O     1 
ATOM   4269  C  CB    . LYS B 1 122 ? 402.961 350.538 239.047 1.00 135.00 ? 122 LYS E CB    1 
ATOM   4270  C  CG    . LYS B 1 122 ? 404.058 349.828 239.853 1.00 136.32 ? 122 LYS E CG    1 
ATOM   4271  C  CD    . LYS B 1 122 ? 403.437 348.981 240.972 1.00 138.72 ? 122 LYS E CD    1 
ATOM   4272  C  CE    . LYS B 1 122 ? 404.471 348.219 241.810 1.00 137.88 ? 122 LYS E CE    1 
ATOM   4273  N  NZ    . LYS B 1 122 ? 403.882 347.415 242.911 1.00 135.05 ? 122 LYS E NZ    1 
ATOM   4274  N  N     . GLU B 1 123 ? 401.492 352.932 237.420 1.00 127.68 ? 123 GLU E N     1 
ATOM   4275  C  CA    . GLU B 1 123 ? 400.411 353.433 236.572 1.00 131.97 ? 123 GLU E CA    1 
ATOM   4276  C  C     . GLU B 1 123 ? 400.941 353.926 235.227 1.00 133.60 ? 123 GLU E C     1 
ATOM   4277  O  O     . GLU B 1 123 ? 400.378 353.600 234.172 1.00 138.58 ? 123 GLU E O     1 
ATOM   4278  C  CB    . GLU B 1 123 ? 399.648 354.550 237.289 1.00 130.17 ? 123 GLU E CB    1 
ATOM   4279  C  CG    . GLU B 1 123 ? 398.901 354.107 238.546 1.00 132.21 ? 123 GLU E CG    1 
ATOM   4280  C  CD    . GLU B 1 123 ? 397.737 353.175 238.251 1.00 131.72 ? 123 GLU E CD    1 
ATOM   4281  O  OE1   . GLU B 1 123 ? 397.336 353.070 237.073 1.00 132.65 ? 123 GLU E OE1   1 
ATOM   4282  O  OE2   . GLU B 1 123 ? 397.223 352.546 239.199 1.00 127.65 ? 123 GLU E OE2   1 
ATOM   4283  N  N     . ALA B 1 124 ? 402.045 354.680 235.244 1.00 125.04 ? 124 ALA E N     1 
ATOM   4284  C  CA    . ALA B 1 124 ? 402.580 355.264 234.017 1.00 123.81 ? 124 ALA E CA    1 
ATOM   4285  C  C     . ALA B 1 124 ? 403.043 354.186 233.046 1.00 124.80 ? 124 ALA E C     1 
ATOM   4286  O  O     . ALA B 1 124 ? 402.799 354.282 231.837 1.00 121.14 ? 124 ALA E O     1 
ATOM   4287  C  CB    . ALA B 1 124 ? 403.727 356.214 234.352 1.00 119.15 ? 124 ALA E CB    1 
ATOM   4288  N  N     . GLU B 1 125 ? 403.709 353.146 233.553 1.00 138.60 ? 125 GLU E N     1 
ATOM   4289  C  CA    . GLU B 1 125 ? 404.054 352.020 232.695 1.00 138.69 ? 125 GLU E CA    1 
ATOM   4290  C  C     . GLU B 1 125 ? 402.821 351.238 232.265 1.00 136.43 ? 125 GLU E C     1 
ATOM   4291  O  O     . GLU B 1 125 ? 402.846 350.609 231.202 1.00 135.56 ? 125 GLU E O     1 
ATOM   4292  C  CB    . GLU B 1 125 ? 405.038 351.069 233.393 1.00 138.80 ? 125 GLU E CB    1 
ATOM   4293  C  CG    . GLU B 1 125 ? 406.370 351.663 233.907 1.00 138.00 ? 125 GLU E CG    1 
ATOM   4294  C  CD    . GLU B 1 125 ? 406.807 352.946 233.219 1.00 138.66 ? 125 GLU E CD    1 
ATOM   4295  O  OE1   . GLU B 1 125 ? 406.897 352.960 231.974 1.00 139.07 ? 125 GLU E OE1   1 
ATOM   4296  O  OE2   . GLU B 1 125 ? 407.055 353.943 233.929 1.00 139.42 ? 125 GLU E OE2   1 
ATOM   4297  N  N     . SER B 1 126 ? 401.743 351.261 233.055 1.00 140.39 ? 126 SER E N     1 
ATOM   4298  C  CA    . SER B 1 126 ? 400.515 350.616 232.609 1.00 140.06 ? 126 SER E CA    1 
ATOM   4299  C  C     . SER B 1 126 ? 399.907 351.342 231.415 1.00 138.86 ? 126 SER E C     1 
ATOM   4300  O  O     . SER B 1 126 ? 399.286 350.700 230.560 1.00 137.70 ? 126 SER E O     1 
ATOM   4301  C  CB    . SER B 1 126 ? 399.505 350.540 233.756 1.00 142.45 ? 126 SER E CB    1 
ATOM   4302  O  OG    . SER B 1 126 ? 398.419 349.681 233.441 1.00 141.83 ? 126 SER E OG    1 
ATOM   4303  N  N     . CYS B 1 127 ? 400.143 352.656 231.326 1.00 146.88 ? 127 CYS E N     1 
ATOM   4304  C  CA    . CYS B 1 127 ? 399.639 353.451 230.173 1.00 146.34 ? 127 CYS E CA    1 
ATOM   4305  C  C     . CYS B 1 127 ? 400.535 353.212 228.954 1.00 145.54 ? 127 CYS E C     1 
ATOM   4306  O  O     . CYS B 1 127 ? 401.770 353.224 229.124 1.00 143.14 ? 127 CYS E O     1 
ATOM   4307  C  CB    . CYS B 1 127 ? 399.662 354.940 230.494 1.00 145.21 ? 127 CYS E CB    1 
ATOM   4308  S  SG    . CYS B 1 127 ? 398.532 355.411 231.829 1.00 154.18 ? 127 CYS E SG    1 
ATOM   4309  N  N     . ASP B 1 128 ? 399.940 353.006 227.773 1.00 159.86 ? 128 ASP E N     1 
ATOM   4310  C  CA    . ASP B 1 128 ? 400.749 352.843 226.532 1.00 160.79 ? 128 ASP E CA    1 
ATOM   4311  C  C     . ASP B 1 128 ? 401.199 354.224 226.040 1.00 158.57 ? 128 ASP E C     1 
ATOM   4312  O  O     . ASP B 1 128 ? 402.347 354.334 225.568 1.00 159.38 ? 128 ASP E O     1 
ATOM   4313  C  CB    . ASP B 1 128 ? 400.003 352.031 225.466 1.00 160.41 ? 128 ASP E CB    1 
ATOM   4314  C  CG    . ASP B 1 128 ? 399.849 350.549 225.768 1.00 159.22 ? 128 ASP E CG    1 
ATOM   4315  O  OD1   . ASP B 1 128 ? 400.551 350.048 226.666 1.00 161.27 ? 128 ASP E OD1   1 
ATOM   4316  O  OD2   . ASP B 1 128 ? 399.019 349.904 225.098 1.00 160.04 ? 128 ASP E OD2   1 
ATOM   4317  N  N     . CYS B 1 129 ? 400.328 355.232 226.150 1.00 146.54 ? 129 CYS E N     1 
ATOM   4318  C  CA    . CYS B 1 129 ? 400.671 356.614 225.722 1.00 143.10 ? 129 CYS E CA    1 
ATOM   4319  C  C     . CYS B 1 129 ? 400.346 357.576 226.866 1.00 143.78 ? 129 CYS E C     1 
ATOM   4320  O  O     . CYS B 1 129 ? 399.149 357.774 227.142 1.00 147.49 ? 129 CYS E O     1 
ATOM   4321  C  CB    . CYS B 1 129 ? 399.871 357.016 224.490 1.00 144.00 ? 129 CYS E CB    1 
ATOM   4322  S  SG    . CYS B 1 129 ? 400.297 358.659 223.856 1.00 152.27 ? 129 CYS E SG    1 
ATOM   4323  N  N     . LEU B 1 130 ? 401.367 358.157 227.501 1.00 120.31 ? 130 LEU E N     1 
ATOM   4324  C  CA    . LEU B 1 130 ? 401.094 359.000 228.660 1.00 117.95 ? 130 LEU E CA    1 
ATOM   4325  C  C     . LEU B 1 130 ? 401.023 360.457 228.225 1.00 117.98 ? 130 LEU E C     1 
ATOM   4326  O  O     . LEU B 1 130 ? 402.048 361.056 227.886 1.00 121.12 ? 130 LEU E O     1 
ATOM   4327  C  CB    . LEU B 1 130 ? 402.173 358.797 229.723 1.00 119.94 ? 130 LEU E CB    1 
ATOM   4328  C  CG    . LEU B 1 130 ? 402.128 359.642 231.000 1.00 121.09 ? 130 LEU E CG    1 
ATOM   4329  C  CD1   . LEU B 1 130 ? 400.834 359.455 231.781 1.00 116.90 ? 130 LEU E CD1   1 
ATOM   4330  C  CD2   . LEU B 1 130 ? 403.318 359.300 231.874 1.00 127.23 ? 130 LEU E CD2   1 
ATOM   4331  N  N     . GLN B 1 131 ? 399.818 361.022 228.240 1.00 114.58 ? 131 GLN E N     1 
ATOM   4332  C  CA    . GLN B 1 131 ? 399.645 362.468 228.217 1.00 111.52 ? 131 GLN E CA    1 
ATOM   4333  C  C     . GLN B 1 131 ? 399.857 362.967 229.649 1.00 112.85 ? 131 GLN E C     1 
ATOM   4334  O  O     . GLN B 1 131 ? 400.342 362.234 230.515 1.00 114.03 ? 131 GLN E O     1 
ATOM   4335  C  CB    . GLN B 1 131 ? 398.279 362.835 227.630 1.00 111.51 ? 131 GLN E CB    1 
ATOM   4336  C  CG    . GLN B 1 131 ? 398.185 364.260 227.033 1.00 108.88 ? 131 GLN E CG    1 
ATOM   4337  C  CD    . GLN B 1 131 ? 397.348 364.360 225.768 1.00 110.82 ? 131 GLN E CD    1 
ATOM   4338  O  OE1   . GLN B 1 131 ? 397.704 365.088 224.843 1.00 107.23 ? 131 GLN E OE1   1 
ATOM   4339  N  NE2   . GLN B 1 131 ? 396.203 363.689 225.747 1.00 115.87 ? 131 GLN E NE2   1 
ATOM   4340  N  N     . GLY B 1 132 ? 399.498 364.211 229.935 1.00 114.44 ? 132 GLY E N     1 
ATOM   4341  C  CA    . GLY B 1 132 ? 399.885 364.822 231.184 1.00 117.65 ? 132 GLY E CA    1 
ATOM   4342  C  C     . GLY B 1 132 ? 399.167 364.254 232.396 1.00 115.38 ? 132 GLY E C     1 
ATOM   4343  O  O     . GLY B 1 132 ? 398.219 363.473 232.309 1.00 118.15 ? 132 GLY E O     1 
ATOM   4344  N  N     . PHE B 1 133 ? 399.651 364.676 233.562 1.00 98.80  ? 133 PHE E N     1 
ATOM   4345  C  CA    . PHE B 1 133 ? 399.108 364.290 234.852 1.00 94.01  ? 133 PHE E CA    1 
ATOM   4346  C  C     . PHE B 1 133 ? 397.987 365.257 235.223 1.00 97.57  ? 133 PHE E C     1 
ATOM   4347  O  O     . PHE B 1 133 ? 397.700 366.213 234.501 1.00 104.40 ? 133 PHE E O     1 
ATOM   4348  C  CB    . PHE B 1 133 ? 400.208 364.292 235.919 1.00 94.85  ? 133 PHE E CB    1 
ATOM   4349  C  CG    . PHE B 1 133 ? 401.304 363.285 235.681 1.00 95.30  ? 133 PHE E CG    1 
ATOM   4350  C  CD1   . PHE B 1 133 ? 402.339 363.556 234.801 1.00 99.23  ? 133 PHE E CD1   1 
ATOM   4351  C  CD2   . PHE B 1 133 ? 401.310 362.077 236.354 1.00 101.61 ? 133 PHE E CD2   1 
ATOM   4352  C  CE1   . PHE B 1 133 ? 403.345 362.637 234.587 1.00 103.43 ? 133 PHE E CE1   1 
ATOM   4353  C  CE2   . PHE B 1 133 ? 402.317 361.153 236.142 1.00 101.67 ? 133 PHE E CE2   1 
ATOM   4354  C  CZ    . PHE B 1 133 ? 403.335 361.436 235.259 1.00 102.60 ? 133 PHE E CZ    1 
ATOM   4355  N  N     . GLN B 1 134 ? 397.334 364.997 236.354 1.00 92.14  ? 134 GLN E N     1 
ATOM   4356  C  CA    . GLN B 1 134 ? 396.353 365.940 236.885 1.00 91.80  ? 134 GLN E CA    1 
ATOM   4357  C  C     . GLN B 1 134 ? 396.340 365.797 238.397 1.00 98.56  ? 134 GLN E C     1 
ATOM   4358  O  O     . GLN B 1 134 ? 395.886 364.771 238.910 1.00 110.60 ? 134 GLN E O     1 
ATOM   4359  C  CB    . GLN B 1 134 ? 394.964 365.692 236.260 1.00 94.60  ? 134 GLN E CB    1 
ATOM   4360  C  CG    . GLN B 1 134 ? 393.707 366.187 237.017 1.00 105.60 ? 134 GLN E CG    1 
ATOM   4361  C  CD    . GLN B 1 134 ? 392.426 365.706 236.364 1.00 110.62 ? 134 GLN E CD    1 
ATOM   4362  O  OE1   . GLN B 1 134 ? 392.265 365.811 235.149 1.00 112.05 ? 134 GLN E OE1   1 
ATOM   4363  N  NE2   . GLN B 1 134 ? 391.491 365.209 237.169 1.00 106.99 ? 134 GLN E NE2   1 
ATOM   4364  N  N     . LEU B 1 135 ? 396.819 366.824 239.099 1.00 89.57  ? 135 LEU E N     1 
ATOM   4365  C  CA    . LEU B 1 135 ? 396.849 366.855 240.555 1.00 91.06  ? 135 LEU E CA    1 
ATOM   4366  C  C     . LEU B 1 135 ? 395.728 367.743 241.074 1.00 90.40  ? 135 LEU E C     1 
ATOM   4367  O  O     . LEU B 1 135 ? 395.438 368.792 240.491 1.00 99.54  ? 135 LEU E O     1 
ATOM   4368  C  CB    . LEU B 1 135 ? 398.194 367.368 241.082 1.00 93.69  ? 135 LEU E CB    1 
ATOM   4369  C  CG    . LEU B 1 135 ? 398.382 367.442 242.607 1.00 97.69  ? 135 LEU E CG    1 
ATOM   4370  C  CD1   . LEU B 1 135 ? 398.273 366.078 243.294 1.00 102.57 ? 135 LEU E CD1   1 
ATOM   4371  C  CD2   . LEU B 1 135 ? 399.704 368.095 242.919 1.00 97.18  ? 135 LEU E CD2   1 
ATOM   4372  N  N     . THR B 1 136 ? 395.098 367.307 242.166 1.00 80.02  ? 136 THR E N     1 
ATOM   4373  C  CA    . THR B 1 136 ? 394.137 368.115 242.913 1.00 80.33  ? 136 THR E CA    1 
ATOM   4374  C  C     . THR B 1 136 ? 394.683 368.341 244.314 1.00 88.63  ? 136 THR E C     1 
ATOM   4375  O  O     . THR B 1 136 ? 395.180 367.404 244.949 1.00 95.93  ? 136 THR E O     1 
ATOM   4376  C  CB    . THR B 1 136 ? 392.758 367.452 242.983 1.00 90.43  ? 136 THR E CB    1 
ATOM   4377  O  OG1   . THR B 1 136 ? 392.842 366.211 243.688 1.00 101.31 ? 136 THR E OG1   1 
ATOM   4378  C  CG2   . THR B 1 136 ? 392.223 367.199 241.596 1.00 87.57  ? 136 THR E CG2   1 
ATOM   4379  N  N     . HIS B 1 137 ? 394.616 369.588 244.777 1.00 96.02  ? 137 HIS E N     1 
ATOM   4380  C  CA    . HIS B 1 137 ? 395.195 369.969 246.058 1.00 95.41  ? 137 HIS E CA    1 
ATOM   4381  C  C     . HIS B 1 137 ? 394.753 371.384 246.399 1.00 97.13  ? 137 HIS E C     1 
ATOM   4382  O  O     . HIS B 1 137 ? 394.227 372.110 245.552 1.00 101.88 ? 137 HIS E O     1 
ATOM   4383  C  CB    . HIS B 1 137 ? 396.728 369.889 246.041 1.00 92.87  ? 137 HIS E CB    1 
ATOM   4384  C  CG    . HIS B 1 137 ? 397.380 370.876 245.121 1.00 91.13  ? 137 HIS E CG    1 
ATOM   4385  N  ND1   . HIS B 1 137 ? 398.373 371.734 245.540 1.00 99.04  ? 137 HIS E ND1   1 
ATOM   4386  C  CD2   . HIS B 1 137 ? 397.189 371.138 243.806 1.00 91.68  ? 137 HIS E CD2   1 
ATOM   4387  C  CE1   . HIS B 1 137 ? 398.763 372.483 244.525 1.00 101.15 ? 137 HIS E CE1   1 
ATOM   4388  N  NE2   . HIS B 1 137 ? 398.058 372.143 243.461 1.00 95.53  ? 137 HIS E NE2   1 
ATOM   4389  N  N     . SER B 1 138 ? 394.977 371.758 247.658 1.00 103.93 ? 138 SER E N     1 
ATOM   4390  C  CA    . SER B 1 138 ? 394.726 373.102 248.165 1.00 106.06 ? 138 SER E CA    1 
ATOM   4391  C  C     . SER B 1 138 ? 396.049 373.774 248.500 1.00 106.73 ? 138 SER E C     1 
ATOM   4392  O  O     . SER B 1 138 ? 396.909 373.170 249.148 1.00 109.75 ? 138 SER E O     1 
ATOM   4393  C  CB    . SER B 1 138 ? 393.841 373.059 249.409 1.00 108.45 ? 138 SER E CB    1 
ATOM   4394  O  OG    . SER B 1 138 ? 394.042 374.211 250.207 1.00 110.41 ? 138 SER E OG    1 
ATOM   4395  N  N     . LEU B 1 139 ? 396.209 375.024 248.062 1.00 100.28 ? 139 LEU E N     1 
ATOM   4396  C  CA    . LEU B 1 139 ? 397.427 375.760 248.383 1.00 101.49 ? 139 LEU E CA    1 
ATOM   4397  C  C     . LEU B 1 139 ? 397.500 376.113 249.862 1.00 105.81 ? 139 LEU E C     1 
ATOM   4398  O  O     . LEU B 1 139 ? 398.594 376.140 250.437 1.00 113.89 ? 139 LEU E O     1 
ATOM   4399  C  CB    . LEU B 1 139 ? 397.515 377.034 247.542 1.00 97.03  ? 139 LEU E CB    1 
ATOM   4400  C  CG    . LEU B 1 139 ? 397.369 376.915 246.023 1.00 93.00  ? 139 LEU E CG    1 
ATOM   4401  C  CD1   . LEU B 1 139 ? 397.760 378.224 245.360 1.00 97.69  ? 139 LEU E CD1   1 
ATOM   4402  C  CD2   . LEU B 1 139 ? 398.198 375.774 245.456 1.00 95.21  ? 139 LEU E CD2   1 
ATOM   4403  N  N     . GLY B 1 140 ? 396.356 376.381 250.496 1.00 107.53 ? 140 GLY E N     1 
ATOM   4404  C  CA    . GLY B 1 140 ? 396.364 376.835 251.874 1.00 107.96 ? 140 GLY E CA    1 
ATOM   4405  C  C     . GLY B 1 140 ? 396.748 375.783 252.889 1.00 108.59 ? 140 GLY E C     1 
ATOM   4406  O  O     . GLY B 1 140 ? 397.229 376.132 253.971 1.00 108.70 ? 140 GLY E O     1 
ATOM   4407  N  N     . GLY B 1 141 ? 396.552 374.507 252.572 1.00 122.18 ? 141 GLY E N     1 
ATOM   4408  C  CA    . GLY B 1 141 ? 396.842 373.458 253.522 1.00 122.80 ? 141 GLY E CA    1 
ATOM   4409  C  C     . GLY B 1 141 ? 398.325 373.173 253.649 1.00 119.53 ? 141 GLY E C     1 
ATOM   4410  O  O     . GLY B 1 141 ? 399.151 373.636 252.863 1.00 122.75 ? 141 GLY E O     1 
ATOM   4411  N  N     . GLY B 1 142 ? 398.656 372.391 254.673 1.00 98.21  ? 142 GLY E N     1 
ATOM   4412  C  CA    . GLY B 1 142 ? 400.012 371.917 254.856 1.00 95.40  ? 142 GLY E CA    1 
ATOM   4413  C  C     . GLY B 1 142 ? 400.271 370.677 254.034 1.00 100.04 ? 142 GLY E C     1 
ATOM   4414  O  O     . GLY B 1 142 ? 401.215 370.645 253.237 1.00 106.09 ? 142 GLY E O     1 
ATOM   4415  N  N     . THR B 1 143 ? 399.427 369.655 254.228 1.00 110.15 ? 143 THR E N     1 
ATOM   4416  C  CA    . THR B 1 143 ? 399.573 368.408 253.484 1.00 111.76 ? 143 THR E CA    1 
ATOM   4417  C  C     . THR B 1 143 ? 399.482 368.655 251.989 1.00 107.49 ? 143 THR E C     1 
ATOM   4418  O  O     . THR B 1 143 ? 400.385 368.276 251.243 1.00 108.90 ? 143 THR E O     1 
ATOM   4419  C  CB    . THR B 1 143 ? 398.506 367.392 253.902 1.00 115.90 ? 143 THR E CB    1 
ATOM   4420  O  OG1   . THR B 1 143 ? 398.669 367.043 255.282 1.00 123.93 ? 143 THR E OG1   1 
ATOM   4421  C  CG2   . THR B 1 143 ? 398.597 366.130 253.044 1.00 109.80 ? 143 THR E CG2   1 
ATOM   4422  N  N     . GLY B 1 144 ? 398.412 369.322 251.544 1.00 105.79 ? 144 GLY E N     1 
ATOM   4423  C  CA    . GLY B 1 144 ? 398.200 369.502 250.115 1.00 103.93 ? 144 GLY E CA    1 
ATOM   4424  C  C     . GLY B 1 144 ? 399.321 370.280 249.456 1.00 102.91 ? 144 GLY E C     1 
ATOM   4425  O  O     . GLY B 1 144 ? 399.894 369.837 248.460 1.00 103.27 ? 144 GLY E O     1 
ATOM   4426  N  N     . SER B 1 145 ? 399.714 371.396 250.069 1.00 104.00 ? 145 SER E N     1 
ATOM   4427  C  CA    . SER B 1 145 ? 400.778 372.228 249.518 1.00 103.35 ? 145 SER E CA    1 
ATOM   4428  C  C     . SER B 1 145 ? 402.110 371.484 249.484 1.00 109.28 ? 145 SER E C     1 
ATOM   4429  O  O     . SER B 1 145 ? 402.763 371.405 248.435 1.00 109.21 ? 145 SER E O     1 
ATOM   4430  C  CB    . SER B 1 145 ? 400.892 373.511 250.337 1.00 102.93 ? 145 SER E CB    1 
ATOM   4431  O  OG    . SER B 1 145 ? 399.613 374.080 250.546 1.00 113.87 ? 145 SER E OG    1 
ATOM   4432  N  N     . GLY B 1 146 ? 402.526 370.911 250.618 1.00 112.97 ? 146 GLY E N     1 
ATOM   4433  C  CA    . GLY B 1 146 ? 403.837 370.281 250.672 1.00 104.62 ? 146 GLY E CA    1 
ATOM   4434  C  C     . GLY B 1 146 ? 403.938 369.044 249.798 1.00 108.37 ? 146 GLY E C     1 
ATOM   4435  O  O     . GLY B 1 146 ? 404.898 368.892 249.026 1.00 114.22 ? 146 GLY E O     1 
ATOM   4436  N  N     . MET B 1 147 ? 402.952 368.142 249.904 1.00 105.06 ? 147 MET E N     1 
ATOM   4437  C  CA    . MET B 1 147 ? 402.990 366.933 249.094 1.00 104.87 ? 147 MET E CA    1 
ATOM   4438  C  C     . MET B 1 147 ? 402.875 367.283 247.625 1.00 108.54 ? 147 MET E C     1 
ATOM   4439  O  O     . MET B 1 147 ? 403.550 366.678 246.791 1.00 111.75 ? 147 MET E O     1 
ATOM   4440  C  CB    . MET B 1 147 ? 401.861 365.963 249.464 1.00 112.62 ? 147 MET E CB    1 
ATOM   4441  C  CG    . MET B 1 147 ? 402.213 364.726 250.293 1.00 115.41 ? 147 MET E CG    1 
ATOM   4442  S  SD    . MET B 1 147 ? 403.623 363.724 249.795 1.00 119.52 ? 147 MET E SD    1 
ATOM   4443  C  CE    . MET B 1 147 ? 403.977 362.922 251.350 1.00 112.44 ? 147 MET E CE    1 
ATOM   4444  N  N     . GLY B 1 148 ? 402.032 368.264 247.283 1.00 107.05 ? 148 GLY E N     1 
ATOM   4445  C  CA    . GLY B 1 148 ? 401.908 368.652 245.896 1.00 108.10 ? 148 GLY E CA    1 
ATOM   4446  C  C     . GLY B 1 148 ? 403.201 369.200 245.337 1.00 110.17 ? 148 GLY E C     1 
ATOM   4447  O  O     . GLY B 1 148 ? 403.601 368.841 244.236 1.00 114.26 ? 148 GLY E O     1 
ATOM   4448  N  N     . THR B 1 149 ? 403.901 370.029 246.112 1.00 108.57 ? 149 THR E N     1 
ATOM   4449  C  CA    . THR B 1 149 ? 405.160 370.586 245.631 1.00 110.25 ? 149 THR E CA    1 
ATOM   4450  C  C     . THR B 1 149 ? 406.203 369.494 245.423 1.00 111.39 ? 149 THR E C     1 
ATOM   4451  O  O     . THR B 1 149 ? 406.868 369.446 244.378 1.00 116.48 ? 149 THR E O     1 
ATOM   4452  C  CB    . THR B 1 149 ? 405.663 371.637 246.615 1.00 118.11 ? 149 THR E CB    1 
ATOM   4453  O  OG1   . THR B 1 149 ? 405.464 371.176 247.957 1.00 123.18 ? 149 THR E OG1   1 
ATOM   4454  C  CG2   . THR B 1 149 ? 404.887 372.917 246.438 1.00 115.72 ? 149 THR E CG2   1 
ATOM   4455  N  N     . LEU B 1 150 ? 406.334 368.581 246.390 1.00 100.09 ? 150 LEU E N     1 
ATOM   4456  C  CA    . LEU B 1 150 ? 407.347 367.533 246.278 1.00 103.11 ? 150 LEU E CA    1 
ATOM   4457  C  C     . LEU B 1 150 ? 407.019 366.567 245.137 1.00 109.55 ? 150 LEU E C     1 
ATOM   4458  O  O     . LEU B 1 150 ? 407.895 366.205 244.339 1.00 108.66 ? 150 LEU E O     1 
ATOM   4459  C  CB    . LEU B 1 150 ? 407.468 366.797 247.612 1.00 99.42  ? 150 LEU E CB    1 
ATOM   4460  C  CG    . LEU B 1 150 ? 408.588 365.766 247.766 1.00 107.01 ? 150 LEU E CG    1 
ATOM   4461  C  CD1   . LEU B 1 150 ? 409.951 366.440 247.796 1.00 106.84 ? 150 LEU E CD1   1 
ATOM   4462  C  CD2   . LEU B 1 150 ? 408.369 364.947 249.023 1.00 109.03 ? 150 LEU E CD2   1 
ATOM   4463  N  N     . LEU B 1 151 ? 405.750 366.154 245.039 1.00 105.21 ? 151 LEU E N     1 
ATOM   4464  C  CA    . LEU B 1 151 ? 405.302 365.295 243.946 1.00 96.87  ? 151 LEU E CA    1 
ATOM   4465  C  C     . LEU B 1 151 ? 405.498 365.952 242.592 1.00 100.49 ? 151 LEU E C     1 
ATOM   4466  O  O     . LEU B 1 151 ? 405.949 365.301 241.647 1.00 107.07 ? 151 LEU E O     1 
ATOM   4467  C  CB    . LEU B 1 151 ? 403.825 364.946 244.126 1.00 97.95  ? 151 LEU E CB    1 
ATOM   4468  C  CG    . LEU B 1 151 ? 403.341 364.108 245.309 1.00 99.34  ? 151 LEU E CG    1 
ATOM   4469  C  CD1   . LEU B 1 151 ? 401.820 364.033 245.330 1.00 102.08 ? 151 LEU E CD1   1 
ATOM   4470  C  CD2   . LEU B 1 151 ? 403.903 362.691 245.277 1.00 103.02 ? 151 LEU E CD2   1 
ATOM   4471  N  N     . ILE B 1 152 ? 405.140 367.229 242.473 1.00 103.51 ? 152 ILE E N     1 
ATOM   4472  C  CA    . ILE B 1 152 ? 405.258 367.934 241.203 1.00 103.08 ? 152 ILE E CA    1 
ATOM   4473  C  C     . ILE B 1 152 ? 406.720 368.006 240.784 1.00 108.14 ? 152 ILE E C     1 
ATOM   4474  O  O     . ILE B 1 152 ? 407.066 367.739 239.625 1.00 111.40 ? 152 ILE E O     1 
ATOM   4475  C  CB    . ILE B 1 152 ? 404.609 369.328 241.328 1.00 103.83 ? 152 ILE E CB    1 
ATOM   4476  C  CG1   . ILE B 1 152 ? 403.080 369.178 241.349 1.00 103.76 ? 152 ILE E CG1   1 
ATOM   4477  C  CG2   . ILE B 1 152 ? 405.057 370.250 240.182 1.00 111.67 ? 152 ILE E CG2   1 
ATOM   4478  C  CD1   . ILE B 1 152 ? 402.302 370.422 241.720 1.00 105.81 ? 152 ILE E CD1   1 
ATOM   4479  N  N     . SER B 1 153 ? 407.602 368.329 241.735 1.00 106.55 ? 153 SER E N     1 
ATOM   4480  C  CA    . SER B 1 153 ? 409.025 368.407 241.424 1.00 106.18 ? 153 SER E CA    1 
ATOM   4481  C  C     . SER B 1 153 ? 409.580 367.056 240.988 1.00 110.32 ? 153 SER E C     1 
ATOM   4482  O  O     . SER B 1 153 ? 410.298 366.971 239.986 1.00 111.98 ? 153 SER E O     1 
ATOM   4483  C  CB    . SER B 1 153 ? 409.791 368.927 242.637 1.00 105.31 ? 153 SER E CB    1 
ATOM   4484  O  OG    . SER B 1 153 ? 411.186 368.913 242.397 1.00 111.24 ? 153 SER E OG    1 
ATOM   4485  N  N     . LYS B 1 154 ? 409.235 365.981 241.701 1.00 102.33 ? 154 LYS E N     1 
ATOM   4486  C  CA    . LYS B 1 154 ? 409.805 364.682 241.346 1.00 98.48  ? 154 LYS E CA    1 
ATOM   4487  C  C     . LYS B 1 154 ? 409.221 364.141 240.045 1.00 101.11 ? 154 LYS E C     1 
ATOM   4488  O  O     . LYS B 1 154 ? 409.944 363.521 239.250 1.00 107.00 ? 154 LYS E O     1 
ATOM   4489  C  CB    . LYS B 1 154 ? 409.600 363.680 242.483 1.00 103.23 ? 154 LYS E CB    1 
ATOM   4490  C  CG    . LYS B 1 154 ? 410.821 363.525 243.383 1.00 106.13 ? 154 LYS E CG    1 
ATOM   4491  C  CD    . LYS B 1 154 ? 411.087 364.789 244.192 1.00 105.95 ? 154 LYS E CD    1 
ATOM   4492  C  CE    . LYS B 1 154 ? 412.252 364.618 245.160 1.00 104.15 ? 154 LYS E CE    1 
ATOM   4493  N  NZ    . LYS B 1 154 ? 412.054 363.522 246.150 1.00 103.53 ? 154 LYS E NZ    1 
ATOM   4494  N  N     . ILE B 1 155 ? 407.928 364.364 239.804 1.00 99.67  ? 155 ILE E N     1 
ATOM   4495  C  CA    . ILE B 1 155 ? 407.314 363.904 238.565 1.00 96.86  ? 155 ILE E CA    1 
ATOM   4496  C  C     . ILE B 1 155 ? 407.878 364.681 237.383 1.00 103.19 ? 155 ILE E C     1 
ATOM   4497  O  O     . ILE B 1 155 ? 408.026 364.129 236.290 1.00 106.35 ? 155 ILE E O     1 
ATOM   4498  C  CB    . ILE B 1 155 ? 405.774 363.994 238.676 1.00 94.41  ? 155 ILE E CB    1 
ATOM   4499  C  CG1   . ILE B 1 155 ? 405.300 362.912 239.671 1.00 95.51  ? 155 ILE E CG1   1 
ATOM   4500  C  CG2   . ILE B 1 155 ? 405.074 363.838 237.275 1.00 100.88 ? 155 ILE E CG2   1 
ATOM   4501  C  CD1   . ILE B 1 155 ? 403.796 362.753 239.863 1.00 99.37  ? 155 ILE E CD1   1 
ATOM   4502  N  N     . ARG B 1 156 ? 408.195 365.968 237.569 1.00 109.46 ? 156 ARG E N     1 
ATOM   4503  C  CA    . ARG B 1 156 ? 408.876 366.700 236.504 1.00 108.88 ? 156 ARG E CA    1 
ATOM   4504  C  C     . ARG B 1 156 ? 410.320 366.253 236.338 1.00 111.47 ? 156 ARG E C     1 
ATOM   4505  O  O     . ARG B 1 156 ? 410.861 366.321 235.229 1.00 114.13 ? 156 ARG E O     1 
ATOM   4506  C  CB    . ARG B 1 156 ? 408.820 368.209 236.755 1.00 104.09 ? 156 ARG E CB    1 
ATOM   4507  C  CG    . ARG B 1 156 ? 407.516 368.900 236.345 1.00 108.65 ? 156 ARG E CG    1 
ATOM   4508  C  CD    . ARG B 1 156 ? 407.331 368.957 234.818 1.00 111.91 ? 156 ARG E CD    1 
ATOM   4509  N  NE    . ARG B 1 156 ? 407.738 370.242 234.262 1.00 112.63 ? 156 ARG E NE    1 
ATOM   4510  C  CZ    . ARG B 1 156 ? 407.411 370.695 233.057 1.00 114.37 ? 156 ARG E CZ    1 
ATOM   4511  N  NH1   . ARG B 1 156 ? 406.673 369.985 232.215 1.00 110.49 ? 156 ARG E NH1   1 
ATOM   4512  N  NH2   . ARG B 1 156 ? 407.847 371.894 232.680 1.00 118.14 ? 156 ARG E NH2   1 
ATOM   4513  N  N     . GLU B 1 157 ? 410.974 365.825 237.419 1.00 127.80 ? 157 GLU E N     1 
ATOM   4514  C  CA    . GLU B 1 157 ? 412.321 365.283 237.281 1.00 129.92 ? 157 GLU E CA    1 
ATOM   4515  C  C     . GLU B 1 157 ? 412.320 364.022 236.427 1.00 128.88 ? 157 GLU E C     1 
ATOM   4516  O  O     . GLU B 1 157 ? 413.141 363.885 235.512 1.00 127.92 ? 157 GLU E O     1 
ATOM   4517  C  CB    . GLU B 1 157 ? 412.937 364.996 238.653 1.00 134.17 ? 157 GLU E CB    1 
ATOM   4518  C  CG    . GLU B 1 157 ? 413.657 366.182 239.286 1.00 134.69 ? 157 GLU E CG    1 
ATOM   4519  C  CD    . GLU B 1 157 ? 413.609 366.159 240.803 1.00 136.09 ? 157 GLU E CD    1 
ATOM   4520  O  OE1   . GLU B 1 157 ? 412.574 366.547 241.381 1.00 135.10 ? 157 GLU E OE1   1 
ATOM   4521  O  OE2   . GLU B 1 157 ? 414.613 365.743 241.420 1.00 136.22 ? 157 GLU E OE2   1 
ATOM   4522  N  N     . GLU B 1 158 ? 411.392 363.094 236.698 1.00 127.07 ? 158 GLU E N     1 
ATOM   4523  C  CA    . GLU B 1 158 ? 411.460 361.794 236.028 1.00 127.60 ? 158 GLU E CA    1 
ATOM   4524  C  C     . GLU B 1 158 ? 410.724 361.797 234.687 1.00 126.90 ? 158 GLU E C     1 
ATOM   4525  O  O     . GLU B 1 158 ? 411.100 361.040 233.785 1.00 126.82 ? 158 GLU E O     1 
ATOM   4526  C  CB    . GLU B 1 158 ? 410.884 360.692 236.921 1.00 128.03 ? 158 GLU E CB    1 
ATOM   4527  C  CG    . GLU B 1 158 ? 411.269 359.248 236.494 1.00 133.07 ? 158 GLU E CG    1 
ATOM   4528  C  CD    . GLU B 1 158 ? 410.333 358.588 235.492 1.00 134.19 ? 158 GLU E CD    1 
ATOM   4529  O  OE1   . GLU B 1 158 ? 410.688 357.514 234.971 1.00 133.22 ? 158 GLU E OE1   1 
ATOM   4530  O  OE2   . GLU B 1 158 ? 409.286 359.163 235.168 1.00 135.08 ? 158 GLU E OE2   1 
ATOM   4531  N  N     . TYR B 1 159 ? 409.688 362.634 234.537 1.00 114.20 ? 159 TYR E N     1 
ATOM   4532  C  CA    . TYR B 1 159 ? 408.879 362.756 233.322 1.00 113.32 ? 159 TYR E CA    1 
ATOM   4533  C  C     . TYR B 1 159 ? 408.966 364.199 232.826 1.00 116.47 ? 159 TYR E C     1 
ATOM   4534  O  O     . TYR B 1 159 ? 407.980 364.946 232.891 1.00 117.60 ? 159 TYR E O     1 
ATOM   4535  C  CB    . TYR B 1 159 ? 407.406 362.410 233.561 1.00 116.05 ? 159 TYR E CB    1 
ATOM   4536  C  CG    . TYR B 1 159 ? 407.059 361.078 234.189 1.00 117.59 ? 159 TYR E CG    1 
ATOM   4537  C  CD1   . TYR B 1 159 ? 406.874 360.973 235.558 1.00 119.19 ? 159 TYR E CD1   1 
ATOM   4538  C  CD2   . TYR B 1 159 ? 406.839 359.950 233.412 1.00 114.03 ? 159 TYR E CD2   1 
ATOM   4539  C  CE1   . TYR B 1 159 ? 406.514 359.777 236.146 1.00 121.11 ? 159 TYR E CE1   1 
ATOM   4540  C  CE2   . TYR B 1 159 ? 406.486 358.741 233.989 1.00 113.45 ? 159 TYR E CE2   1 
ATOM   4541  C  CZ    . TYR B 1 159 ? 406.326 358.661 235.358 1.00 119.35 ? 159 TYR E CZ    1 
ATOM   4542  O  OH    . TYR B 1 159 ? 405.977 357.462 235.936 1.00 123.45 ? 159 TYR E OH    1 
ATOM   4543  N  N     . PRO B 1 160 ? 410.127 364.632 232.328 1.00 123.07 ? 160 PRO E N     1 
ATOM   4544  C  CA    . PRO B 1 160 ? 410.238 366.038 231.906 1.00 120.78 ? 160 PRO E CA    1 
ATOM   4545  C  C     . PRO B 1 160 ? 409.382 366.389 230.700 1.00 122.03 ? 160 PRO E C     1 
ATOM   4546  O  O     . PRO B 1 160 ? 408.950 367.542 230.582 1.00 118.10 ? 160 PRO E O     1 
ATOM   4547  C  CB    . PRO B 1 160 ? 411.734 366.192 231.605 1.00 123.74 ? 160 PRO E CB    1 
ATOM   4548  C  CG    . PRO B 1 160 ? 412.179 364.836 231.226 1.00 125.67 ? 160 PRO E CG    1 
ATOM   4549  C  CD    . PRO B 1 160 ? 411.369 363.884 232.069 1.00 124.16 ? 160 PRO E CD    1 
ATOM   4550  N  N     . ASP B 1 161 ? 409.117 365.435 229.807 1.00 135.49 ? 161 ASP E N     1 
ATOM   4551  C  CA    . ASP B 1 161 ? 408.468 365.759 228.541 1.00 134.67 ? 161 ASP E CA    1 
ATOM   4552  C  C     . ASP B 1 161 ? 406.964 365.967 228.673 1.00 131.70 ? 161 ASP E C     1 
ATOM   4553  O  O     . ASP B 1 161 ? 406.382 366.723 227.888 1.00 131.49 ? 161 ASP E O     1 
ATOM   4554  C  CB    . ASP B 1 161 ? 408.741 364.657 227.518 1.00 136.35 ? 161 ASP E CB    1 
ATOM   4555  C  CG    . ASP B 1 161 ? 408.206 364.998 226.142 1.00 137.46 ? 161 ASP E CG    1 
ATOM   4556  O  OD1   . ASP B 1 161 ? 408.481 366.115 225.656 1.00 136.80 ? 161 ASP E OD1   1 
ATOM   4557  O  OD2   . ASP B 1 161 ? 407.505 364.151 225.548 1.00 136.75 ? 161 ASP E OD2   1 
ATOM   4558  N  N     . ARG B 1 162 ? 406.320 365.319 229.637 1.00 125.70 ? 162 ARG E N     1 
ATOM   4559  C  CA    . ARG B 1 162 ? 404.867 365.237 229.653 1.00 126.45 ? 162 ARG E CA    1 
ATOM   4560  C  C     . ARG B 1 162 ? 404.278 366.452 230.360 1.00 127.39 ? 162 ARG E C     1 
ATOM   4561  O  O     . ARG B 1 162 ? 404.899 367.041 231.248 1.00 127.00 ? 162 ARG E O     1 
ATOM   4562  C  CB    . ARG B 1 162 ? 404.400 363.949 230.339 1.00 121.47 ? 162 ARG E CB    1 
ATOM   4563  C  CG    . ARG B 1 162 ? 405.264 362.697 230.082 1.00 124.26 ? 162 ARG E CG    1 
ATOM   4564  C  CD    . ARG B 1 162 ? 405.582 362.400 228.610 1.00 128.33 ? 162 ARG E CD    1 
ATOM   4565  N  NE    . ARG B 1 162 ? 404.391 362.251 227.781 1.00 130.75 ? 162 ARG E NE    1 
ATOM   4566  C  CZ    . ARG B 1 162 ? 404.378 362.241 226.452 1.00 134.58 ? 162 ARG E CZ    1 
ATOM   4567  N  NH1   . ARG B 1 162 ? 405.485 362.378 225.735 1.00 133.76 ? 162 ARG E NH1   1 
ATOM   4568  N  NH2   . ARG B 1 162 ? 403.219 362.075 225.821 1.00 135.31 ? 162 ARG E NH2   1 
ATOM   4569  N  N     . ILE B 1 163 ? 403.066 366.828 229.944 1.00 116.49 ? 163 ILE E N     1 
ATOM   4570  C  CA    . ILE B 1 163 ? 402.432 368.028 230.482 1.00 115.31 ? 163 ILE E CA    1 
ATOM   4571  C  C     . ILE B 1 163 ? 402.079 367.778 231.949 1.00 113.57 ? 163 ILE E C     1 
ATOM   4572  O  O     . ILE B 1 163 ? 401.901 366.634 232.379 1.00 117.38 ? 163 ILE E O     1 
ATOM   4573  C  CB    . ILE B 1 163 ? 401.210 368.420 229.620 1.00 116.39 ? 163 ILE E CB    1 
ATOM   4574  C  CG1   . ILE B 1 163 ? 401.604 369.520 228.625 1.00 124.07 ? 163 ILE E CG1   1 
ATOM   4575  C  CG2   . ILE B 1 163 ? 399.983 368.928 230.422 1.00 112.39 ? 163 ILE E CG2   1 
ATOM   4576  C  CD1   . ILE B 1 163 ? 402.685 369.103 227.656 1.00 123.15 ? 163 ILE E CD1   1 
ATOM   4577  N  N     . MET B 1 164 ? 402.047 368.855 232.737 1.00 114.78 ? 164 MET E N     1 
ATOM   4578  C  CA    . MET B 1 164 ? 401.589 368.812 234.121 1.00 108.97 ? 164 MET E CA    1 
ATOM   4579  C  C     . MET B 1 164 ? 400.427 369.779 234.289 1.00 108.52 ? 164 MET E C     1 
ATOM   4580  O  O     . MET B 1 164 ? 400.537 370.953 233.922 1.00 118.62 ? 164 MET E O     1 
ATOM   4581  C  CB    . MET B 1 164 ? 402.705 369.166 235.096 1.00 107.65 ? 164 MET E CB    1 
ATOM   4582  C  CG    . MET B 1 164 ? 403.544 367.950 235.503 1.00 108.72 ? 164 MET E CG    1 
ATOM   4583  S  SD    . MET B 1 164 ? 402.998 366.895 236.875 1.00 119.45 ? 164 MET E SD    1 
ATOM   4584  C  CE    . MET B 1 164 ? 402.100 367.966 237.983 1.00 110.15 ? 164 MET E CE    1 
ATOM   4585  N  N     . ASN B 1 165 ? 399.323 369.280 234.845 1.00 100.16 ? 165 ASN E N     1 
ATOM   4586  C  CA    . ASN B 1 165 ? 398.125 370.060 235.124 1.00 101.19 ? 165 ASN E CA    1 
ATOM   4587  C  C     . ASN B 1 165 ? 397.814 369.956 236.608 1.00 104.35 ? 165 ASN E C     1 
ATOM   4588  O  O     . ASN B 1 165 ? 397.982 368.892 237.209 1.00 114.09 ? 165 ASN E O     1 
ATOM   4589  C  CB    . ASN B 1 165 ? 396.938 369.549 234.308 1.00 105.54 ? 165 ASN E CB    1 
ATOM   4590  C  CG    . ASN B 1 165 ? 397.072 369.858 232.838 1.00 110.09 ? 165 ASN E CG    1 
ATOM   4591  O  OD1   . ASN B 1 165 ? 398.044 370.481 232.414 1.00 113.91 ? 165 ASN E OD1   1 
ATOM   4592  N  ND2   . ASN B 1 165 ? 396.107 369.407 232.044 1.00 113.41 ? 165 ASN E ND2   1 
ATOM   4593  N  N     . THR B 1 166 ? 397.381 371.068 237.198 1.00 90.90  ? 166 THR E N     1 
ATOM   4594  C  CA    . THR B 1 166 ? 397.013 371.120 238.606 1.00 92.40  ? 166 THR E CA    1 
ATOM   4595  C  C     . THR B 1 166 ? 395.749 371.947 238.759 1.00 93.79  ? 166 THR E C     1 
ATOM   4596  O  O     . THR B 1 166 ? 395.557 372.935 238.047 1.00 98.01  ? 166 THR E O     1 
ATOM   4597  C  CB    . THR B 1 166 ? 398.126 371.725 239.470 1.00 101.01 ? 166 THR E CB    1 
ATOM   4598  O  OG1   . THR B 1 166 ? 398.329 373.092 239.099 1.00 110.06 ? 166 THR E OG1   1 
ATOM   4599  C  CG2   . THR B 1 166 ? 399.426 370.954 239.302 1.00 103.97 ? 166 THR E CG2   1 
ATOM   4600  N  N     . PHE B 1 167 ? 394.889 371.525 239.685 1.00 98.11  ? 167 PHE E N     1 
ATOM   4601  C  CA    . PHE B 1 167 ? 393.667 372.238 240.045 1.00 93.16  ? 167 PHE E CA    1 
ATOM   4602  C  C     . PHE B 1 167 ? 393.803 372.659 241.500 1.00 94.96  ? 167 PHE E C     1 
ATOM   4603  O  O     . PHE B 1 167 ? 393.642 371.835 242.406 1.00 99.30  ? 167 PHE E O     1 
ATOM   4604  C  CB    . PHE B 1 167 ? 392.438 371.361 239.830 1.00 91.32  ? 167 PHE E CB    1 
ATOM   4605  C  CG    . PHE B 1 167 ? 392.049 371.215 238.389 1.00 103.73 ? 167 PHE E CG    1 
ATOM   4606  C  CD1   . PHE B 1 167 ? 392.651 370.260 237.589 1.00 99.68  ? 167 PHE E CD1   1 
ATOM   4607  C  CD2   . PHE B 1 167 ? 391.081 372.033 237.835 1.00 110.93 ? 167 PHE E CD2   1 
ATOM   4608  C  CE1   . PHE B 1 167 ? 392.293 370.123 236.263 1.00 98.36  ? 167 PHE E CE1   1 
ATOM   4609  C  CE2   . PHE B 1 167 ? 390.719 371.902 236.510 1.00 104.87 ? 167 PHE E CE2   1 
ATOM   4610  C  CZ    . PHE B 1 167 ? 391.326 370.946 235.723 1.00 102.23 ? 167 PHE E CZ    1 
ATOM   4611  N  N     . SER B 1 168 ? 394.089 373.940 241.715 1.00 97.12  ? 168 SER E N     1 
ATOM   4612  C  CA    . SER B 1 168 ? 394.474 374.472 243.015 1.00 99.70  ? 168 SER E CA    1 
ATOM   4613  C  C     . SER B 1 168 ? 393.359 375.338 243.577 1.00 101.05 ? 168 SER E C     1 
ATOM   4614  O  O     . SER B 1 168 ? 392.812 376.189 242.868 1.00 104.90 ? 168 SER E O     1 
ATOM   4615  C  CB    . SER B 1 168 ? 395.759 375.290 242.897 1.00 104.79 ? 168 SER E CB    1 
ATOM   4616  O  OG    . SER B 1 168 ? 396.843 374.478 242.484 1.00 100.30 ? 168 SER E OG    1 
ATOM   4617  N  N     . VAL B 1 169 ? 393.033 375.120 244.850 1.00 90.58  ? 169 VAL E N     1 
ATOM   4618  C  CA    . VAL B 1 169 ? 392.067 375.935 245.578 1.00 92.39  ? 169 VAL E CA    1 
ATOM   4619  C  C     . VAL B 1 169 ? 392.842 377.002 246.339 1.00 100.46 ? 169 VAL E C     1 
ATOM   4620  O  O     . VAL B 1 169 ? 393.611 376.682 247.254 1.00 103.00 ? 169 VAL E O     1 
ATOM   4621  C  CB    . VAL B 1 169 ? 391.210 375.081 246.524 1.00 96.99  ? 169 VAL E CB    1 
ATOM   4622  C  CG1   . VAL B 1 169 ? 390.323 375.977 247.400 1.00 102.72 ? 169 VAL E CG1   1 
ATOM   4623  C  CG2   . VAL B 1 169 ? 390.382 374.079 245.714 1.00 96.78  ? 169 VAL E CG2   1 
ATOM   4624  N  N     . VAL B 1 170 ? 392.628 378.264 245.972 1.00 106.24 ? 170 VAL E N     1 
ATOM   4625  C  CA    . VAL B 1 170 ? 393.417 379.390 246.477 1.00 105.37 ? 170 VAL E CA    1 
ATOM   4626  C  C     . VAL B 1 170 ? 392.634 380.116 247.570 1.00 105.46 ? 170 VAL E C     1 
ATOM   4627  O  O     . VAL B 1 170 ? 391.407 379.959 247.641 1.00 106.45 ? 170 VAL E O     1 
ATOM   4628  C  CB    . VAL B 1 170 ? 393.795 380.358 245.342 1.00 100.54 ? 170 VAL E CB    1 
ATOM   4629  C  CG1   . VAL B 1 170 ? 394.474 379.609 244.206 1.00 96.75  ? 170 VAL E CG1   1 
ATOM   4630  C  CG2   . VAL B 1 170 ? 392.577 381.129 244.836 1.00 107.57 ? 170 VAL E CG2   1 
ATOM   4631  N  N     . PRO B 1 171 ? 393.273 380.905 248.440 1.00 108.57 ? 171 PRO E N     1 
ATOM   4632  C  CA    . PRO B 1 171 ? 392.507 381.735 249.382 1.00 112.02 ? 171 PRO E CA    1 
ATOM   4633  C  C     . PRO B 1 171 ? 391.887 382.942 248.689 1.00 117.05 ? 171 PRO E C     1 
ATOM   4634  O  O     . PRO B 1 171 ? 392.166 383.240 247.527 1.00 122.17 ? 171 PRO E O     1 
ATOM   4635  C  CB    . PRO B 1 171 ? 393.549 382.171 250.417 1.00 111.18 ? 171 PRO E CB    1 
ATOM   4636  C  CG    . PRO B 1 171 ? 394.856 382.002 249.746 1.00 110.77 ? 171 PRO E CG    1 
ATOM   4637  C  CD    . PRO B 1 171 ? 394.703 380.872 248.796 1.00 105.24 ? 171 PRO E CD    1 
ATOM   4638  N  N     . SER B 1 172 ? 391.033 383.656 249.444 1.00 118.88 ? 172 SER E N     1 
ATOM   4639  C  CA    . SER B 1 172 ? 390.349 384.862 248.977 1.00 119.66 ? 172 SER E CA    1 
ATOM   4640  C  C     . SER B 1 172 ? 390.650 385.997 249.951 1.00 120.90 ? 172 SER E C     1 
ATOM   4641  O  O     . SER B 1 172 ? 391.284 385.759 250.986 1.00 123.26 ? 172 SER E O     1 
ATOM   4642  C  CB    . SER B 1 172 ? 388.842 384.631 248.886 1.00 117.53 ? 172 SER E CB    1 
ATOM   4643  O  OG    . SER B 1 172 ? 388.254 384.668 250.162 1.00 116.58 ? 172 SER E OG    1 
ATOM   4644  N  N     . PRO B 1 173 ? 390.231 387.239 249.670 1.00 122.89 ? 173 PRO E N     1 
ATOM   4645  C  CA    . PRO B 1 173 ? 390.467 388.305 250.660 1.00 124.75 ? 173 PRO E CA    1 
ATOM   4646  C  C     . PRO B 1 173 ? 389.691 388.121 251.951 1.00 121.28 ? 173 PRO E C     1 
ATOM   4647  O  O     . PRO B 1 173 ? 390.247 388.337 253.035 1.00 118.57 ? 173 PRO E O     1 
ATOM   4648  C  CB    . PRO B 1 173 ? 390.027 389.580 249.922 1.00 125.51 ? 173 PRO E CB    1 
ATOM   4649  C  CG    . PRO B 1 173 ? 389.956 389.219 248.489 1.00 127.10 ? 173 PRO E CG    1 
ATOM   4650  C  CD    . PRO B 1 173 ? 389.630 387.771 248.435 1.00 121.71 ? 173 PRO E CD    1 
ATOM   4651  N  N     . LYS B 1 174 ? 388.427 387.712 251.868 1.00 111.46 ? 174 LYS E N     1 
ATOM   4652  C  CA    . LYS B 1 174 ? 387.501 387.787 252.990 1.00 111.09 ? 174 LYS E CA    1 
ATOM   4653  C  C     . LYS B 1 174 ? 387.340 386.478 253.754 1.00 113.77 ? 174 LYS E C     1 
ATOM   4654  O  O     . LYS B 1 174 ? 386.442 386.391 254.598 1.00 116.36 ? 174 LYS E O     1 
ATOM   4655  C  CB    . LYS B 1 174 ? 386.128 388.252 252.494 1.00 106.90 ? 174 LYS E CB    1 
ATOM   4656  N  N     . VAL B 1 175 ? 388.170 385.463 253.485 1.00 120.21 ? 175 VAL E N     1 
ATOM   4657  C  CA    . VAL B 1 175 ? 388.085 384.169 254.154 1.00 119.30 ? 175 VAL E CA    1 
ATOM   4658  C  C     . VAL B 1 175 ? 389.474 383.751 254.608 1.00 120.26 ? 175 VAL E C     1 
ATOM   4659  O  O     . VAL B 1 175 ? 390.494 384.231 254.110 1.00 122.40 ? 175 VAL E O     1 
ATOM   4660  C  CB    . VAL B 1 175 ? 387.458 383.068 253.258 1.00 120.51 ? 175 VAL E CB    1 
ATOM   4661  C  CG1   . VAL B 1 175 ? 386.242 383.602 252.528 1.00 121.03 ? 175 VAL E CG1   1 
ATOM   4662  C  CG2   . VAL B 1 175 ? 388.472 382.465 252.263 1.00 120.74 ? 175 VAL E CG2   1 
ATOM   4663  N  N     . SER B 1 176 ? 389.496 382.838 255.574 1.00 115.57 ? 176 SER E N     1 
ATOM   4664  C  CA    . SER B 1 176 ? 390.739 382.197 255.980 1.00 115.47 ? 176 SER E CA    1 
ATOM   4665  C  C     . SER B 1 176 ? 390.376 380.917 256.715 1.00 115.27 ? 176 SER E C     1 
ATOM   4666  O  O     . SER B 1 176 ? 389.829 380.977 257.820 1.00 121.96 ? 176 SER E O     1 
ATOM   4667  C  CB    . SER B 1 176 ? 391.568 383.121 256.855 1.00 116.11 ? 176 SER E CB    1 
ATOM   4668  O  OG    . SER B 1 176 ? 390.840 383.532 257.998 1.00 119.49 ? 176 SER E OG    1 
ATOM   4669  N  N     . ASP B 1 177 ? 390.677 379.773 256.105 1.00 116.00 ? 177 ASP E N     1 
ATOM   4670  C  CA    . ASP B 1 177 ? 390.440 378.487 256.741 1.00 118.91 ? 177 ASP E CA    1 
ATOM   4671  C  C     . ASP B 1 177 ? 391.568 378.078 257.675 1.00 121.72 ? 177 ASP E C     1 
ATOM   4672  O  O     . ASP B 1 177 ? 391.330 377.292 258.596 1.00 123.38 ? 177 ASP E O     1 
ATOM   4673  C  CB    . ASP B 1 177 ? 390.238 377.403 255.679 1.00 121.18 ? 177 ASP E CB    1 
ATOM   4674  C  CG    . ASP B 1 177 ? 388.810 377.350 255.164 1.00 123.68 ? 177 ASP E CG    1 
ATOM   4675  O  OD1   . ASP B 1 177 ? 387.879 377.229 255.987 1.00 127.23 ? 177 ASP E OD1   1 
ATOM   4676  O  OD2   . ASP B 1 177 ? 388.615 377.442 253.934 1.00 121.56 ? 177 ASP E OD2   1 
ATOM   4677  N  N     . THR B 1 178 ? 392.785 378.576 257.447 1.00 108.78 ? 178 THR E N     1 
ATOM   4678  C  CA    . THR B 1 178 ? 393.917 378.371 258.340 1.00 107.70 ? 178 THR E CA    1 
ATOM   4679  C  C     . THR B 1 178 ? 394.666 379.686 258.491 1.00 104.27 ? 178 THR E C     1 
ATOM   4680  O  O     . THR B 1 178 ? 394.606 380.557 257.621 1.00 104.65 ? 178 THR E O     1 
ATOM   4681  C  CB    . THR B 1 178 ? 394.892 377.291 257.837 1.00 109.04 ? 178 THR E CB    1 
ATOM   4682  O  OG1   . THR B 1 178 ? 395.838 377.880 256.937 1.00 112.67 ? 178 THR E OG1   1 
ATOM   4683  C  CG2   . THR B 1 178 ? 394.161 376.153 257.135 1.00 111.46 ? 178 THR E CG2   1 
ATOM   4684  N  N     . VAL B 1 179 ? 395.374 379.819 259.614 1.00 104.15 ? 179 VAL E N     1 
ATOM   4685  C  CA    . VAL B 1 179 ? 396.090 381.057 259.901 1.00 101.60 ? 179 VAL E CA    1 
ATOM   4686  C  C     . VAL B 1 179 ? 397.308 381.218 258.995 1.00 103.14 ? 179 VAL E C     1 
ATOM   4687  O  O     . VAL B 1 179 ? 397.656 382.343 258.620 1.00 104.57 ? 179 VAL E O     1 
ATOM   4688  C  CB    . VAL B 1 179 ? 396.484 381.109 261.390 1.00 103.57 ? 179 VAL E CB    1 
ATOM   4689  C  CG1   . VAL B 1 179 ? 397.317 382.358 261.678 1.00 106.91 ? 179 VAL E CG1   1 
ATOM   4690  C  CG2   . VAL B 1 179 ? 395.237 381.069 262.279 1.00 105.83 ? 179 VAL E CG2   1 
ATOM   4691  N  N     . VAL B 1 180 ? 397.959 380.115 258.613 1.00 96.79  ? 180 VAL E N     1 
ATOM   4692  C  CA    . VAL B 1 180 ? 399.235 380.148 257.894 1.00 90.61  ? 180 VAL E CA    1 
ATOM   4693  C  C     . VAL B 1 180 ? 399.030 379.962 256.390 1.00 95.91  ? 180 VAL E C     1 
ATOM   4694  O  O     . VAL B 1 180 ? 399.932 379.486 255.679 1.00 99.42  ? 180 VAL E O     1 
ATOM   4695  C  CB    . VAL B 1 180 ? 400.214 379.096 258.462 1.00 87.04  ? 180 VAL E CB    1 
ATOM   4696  C  CG1   . VAL B 1 180 ? 400.550 379.423 259.908 1.00 87.69  ? 180 VAL E CG1   1 
ATOM   4697  C  CG2   . VAL B 1 180 ? 399.663 377.662 258.371 1.00 88.80  ? 180 VAL E CG2   1 
ATOM   4698  N  N     . GLU B 1 181 ? 397.840 380.330 255.902 1.00 113.88 ? 181 GLU E N     1 
ATOM   4699  C  CA    . GLU B 1 181 ? 397.563 380.241 254.471 1.00 113.05 ? 181 GLU E CA    1 
ATOM   4700  C  C     . GLU B 1 181 ? 398.520 381.061 253.620 1.00 114.16 ? 181 GLU E C     1 
ATOM   4701  O  O     . GLU B 1 181 ? 398.914 380.562 252.555 1.00 121.04 ? 181 GLU E O     1 
ATOM   4702  C  CB    . GLU B 1 181 ? 396.120 380.670 254.166 1.00 115.54 ? 181 GLU E CB    1 
ATOM   4703  C  CG    . GLU B 1 181 ? 395.135 379.529 254.023 1.00 120.25 ? 181 GLU E CG    1 
ATOM   4704  C  CD    . GLU B 1 181 ? 393.724 379.940 254.377 1.00 124.18 ? 181 GLU E CD    1 
ATOM   4705  O  OE1   . GLU B 1 181 ? 393.359 381.100 254.094 1.00 121.79 ? 181 GLU E OE1   1 
ATOM   4706  O  OE2   . GLU B 1 181 ? 392.981 379.109 254.940 1.00 124.57 ? 181 GLU E OE2   1 
ATOM   4707  N  N     . PRO B 1 182 ? 398.882 382.303 253.968 1.00 105.17 ? 182 PRO E N     1 
ATOM   4708  C  CA    . PRO B 1 182 ? 399.896 383.007 253.162 1.00 106.02 ? 182 PRO E CA    1 
ATOM   4709  C  C     . PRO B 1 182 ? 401.230 382.288 253.057 1.00 104.98 ? 182 PRO E C     1 
ATOM   4710  O  O     . PRO B 1 182 ? 401.787 382.218 251.957 1.00 114.71 ? 182 PRO E O     1 
ATOM   4711  C  CB    . PRO B 1 182 ? 400.027 384.349 253.889 1.00 104.33 ? 182 PRO E CB    1 
ATOM   4712  C  CG    . PRO B 1 182 ? 398.669 384.591 254.398 1.00 106.48 ? 182 PRO E CG    1 
ATOM   4713  C  CD    . PRO B 1 182 ? 398.152 383.245 254.835 1.00 107.48 ? 182 PRO E CD    1 
ATOM   4714  N  N     . TYR B 1 183 ? 401.736 381.710 254.150 1.00 89.07  ? 183 TYR E N     1 
ATOM   4715  C  CA    . TYR B 1 183 ? 403.007 380.993 254.084 1.00 92.72  ? 183 TYR E CA    1 
ATOM   4716  C  C     . TYR B 1 183 ? 402.900 379.769 253.185 1.00 93.52  ? 183 TYR E C     1 
ATOM   4717  O  O     . TYR B 1 183 ? 403.723 379.578 252.273 1.00 92.75  ? 183 TYR E O     1 
ATOM   4718  C  CB    . TYR B 1 183 ? 403.449 380.568 255.489 1.00 88.29  ? 183 TYR E CB    1 
ATOM   4719  C  CG    . TYR B 1 183 ? 403.949 381.656 256.435 1.00 84.38  ? 183 TYR E CG    1 
ATOM   4720  C  CD1   . TYR B 1 183 ? 404.069 382.987 256.045 1.00 86.37  ? 183 TYR E CD1   1 
ATOM   4721  C  CD2   . TYR B 1 183 ? 404.318 381.329 257.731 1.00 87.62  ? 183 TYR E CD2   1 
ATOM   4722  C  CE1   . TYR B 1 183 ? 404.530 383.948 256.919 1.00 92.43  ? 183 TYR E CE1   1 
ATOM   4723  C  CE2   . TYR B 1 183 ? 404.779 382.284 258.608 1.00 87.76  ? 183 TYR E CE2   1 
ATOM   4724  C  CZ    . TYR B 1 183 ? 404.883 383.590 258.198 1.00 90.79  ? 183 TYR E CZ    1 
ATOM   4725  O  OH    . TYR B 1 183 ? 405.344 384.542 259.074 1.00 100.09 ? 183 TYR E OH    1 
ATOM   4726  N  N     . ASN B 1 184 ? 401.884 378.930 253.426 1.00 96.60  ? 184 ASN E N     1 
ATOM   4727  C  CA    . ASN B 1 184 ? 401.725 377.720 252.623 1.00 94.81  ? 184 ASN E CA    1 
ATOM   4728  C  C     . ASN B 1 184 ? 401.481 378.059 251.159 1.00 100.30 ? 184 ASN E C     1 
ATOM   4729  O  O     . ASN B 1 184 ? 402.101 377.466 250.265 1.00 109.51 ? 184 ASN E O     1 
ATOM   4730  C  CB    . ASN B 1 184 ? 400.576 376.874 253.168 1.00 98.82  ? 184 ASN E CB    1 
ATOM   4731  C  CG    . ASN B 1 184 ? 400.848 376.343 254.557 1.00 107.72 ? 184 ASN E CG    1 
ATOM   4732  O  OD1   . ASN B 1 184 ? 401.994 376.274 254.996 1.00 109.00 ? 184 ASN E OD1   1 
ATOM   4733  N  ND2   . ASN B 1 184 ? 399.790 375.950 255.252 1.00 112.37 ? 184 ASN E ND2   1 
ATOM   4734  N  N     . ALA B 1 185 ? 400.610 379.039 250.902 1.00 106.43 ? 185 ALA E N     1 
ATOM   4735  C  CA    . ALA B 1 185 ? 400.283 379.438 249.542 1.00 104.66 ? 185 ALA E CA    1 
ATOM   4736  C  C     . ALA B 1 185 ? 401.512 379.960 248.814 1.00 102.07 ? 185 ALA E C     1 
ATOM   4737  O  O     . ALA B 1 185 ? 401.777 379.563 247.675 1.00 105.07 ? 185 ALA E O     1 
ATOM   4738  C  CB    . ALA B 1 185 ? 399.183 380.497 249.567 1.00 102.63 ? 185 ALA E CB    1 
ATOM   4739  N  N     . THR B 1 186 ? 402.292 380.825 249.475 1.00 102.49 ? 186 THR E N     1 
ATOM   4740  C  CA    . THR B 1 186 ? 403.452 381.439 248.840 1.00 101.15 ? 186 THR E CA    1 
ATOM   4741  C  C     . THR B 1 186 ? 404.509 380.401 248.499 1.00 107.78 ? 186 THR E C     1 
ATOM   4742  O  O     . THR B 1 186 ? 405.040 380.389 247.378 1.00 117.13 ? 186 THR E O     1 
ATOM   4743  C  CB    . THR B 1 186 ? 404.037 382.513 249.756 1.00 104.69 ? 186 THR E CB    1 
ATOM   4744  O  OG1   . THR B 1 186 ? 403.056 383.530 249.988 1.00 114.70 ? 186 THR E OG1   1 
ATOM   4745  C  CG2   . THR B 1 186 ? 405.271 383.135 249.132 1.00 103.11 ? 186 THR E CG2   1 
ATOM   4746  N  N     . LEU B 1 187 ? 404.827 379.518 249.453 1.00 103.66 ? 187 LEU E N     1 
ATOM   4747  C  CA    . LEU B 1 187 ? 405.816 378.480 249.178 1.00 101.14 ? 187 LEU E CA    1 
ATOM   4748  C  C     . LEU B 1 187 ? 405.339 377.556 248.065 1.00 101.52 ? 187 LEU E C     1 
ATOM   4749  O  O     . LEU B 1 187 ? 406.129 377.155 247.195 1.00 100.82 ? 187 LEU E O     1 
ATOM   4750  C  CB    . LEU B 1 187 ? 406.118 377.689 250.450 1.00 100.14 ? 187 LEU E CB    1 
ATOM   4751  C  CG    . LEU B 1 187 ? 406.819 378.478 251.561 1.00 97.21  ? 187 LEU E CG    1 
ATOM   4752  C  CD1   . LEU B 1 187 ? 406.608 377.811 252.905 1.00 96.33  ? 187 LEU E CD1   1 
ATOM   4753  C  CD2   . LEU B 1 187 ? 408.302 378.618 251.266 1.00 103.47 ? 187 LEU E CD2   1 
ATOM   4754  N  N     . SER B 1 188 ? 404.039 377.246 248.045 1.00 108.39 ? 188 SER E N     1 
ATOM   4755  C  CA    . SER B 1 188 ? 403.514 376.382 246.998 1.00 104.99 ? 188 SER E CA    1 
ATOM   4756  C  C     . SER B 1 188 ? 403.629 377.031 245.624 1.00 106.13 ? 188 SER E C     1 
ATOM   4757  O  O     . SER B 1 188 ? 404.024 376.367 244.664 1.00 110.49 ? 188 SER E O     1 
ATOM   4758  C  CB    . SER B 1 188 ? 402.065 376.001 247.292 1.00 106.68 ? 188 SER E CB    1 
ATOM   4759  O  OG    . SER B 1 188 ? 401.393 377.042 247.958 1.00 116.51 ? 188 SER E OG    1 
ATOM   4760  N  N     . VAL B 1 189 ? 403.290 378.322 245.497 1.00 110.65 ? 189 VAL E N     1 
ATOM   4761  C  CA    . VAL B 1 189 ? 403.335 378.905 244.150 1.00 111.79 ? 189 VAL E CA    1 
ATOM   4762  C  C     . VAL B 1 189 ? 404.786 379.044 243.714 1.00 113.80 ? 189 VAL E C     1 
ATOM   4763  O  O     . VAL B 1 189 ? 405.103 378.879 242.528 1.00 116.75 ? 189 VAL E O     1 
ATOM   4764  C  CB    . VAL B 1 189 ? 402.622 380.272 244.014 1.00 109.99 ? 189 VAL E CB    1 
ATOM   4765  C  CG1   . VAL B 1 189 ? 403.002 381.265 245.097 1.00 115.39 ? 189 VAL E CG1   1 
ATOM   4766  C  CG2   . VAL B 1 189 ? 402.828 380.873 242.616 1.00 113.49 ? 189 VAL E CG2   1 
ATOM   4767  N  N     . HIS B 1 190 ? 405.684 379.346 244.661 1.00 107.35 ? 190 HIS E N     1 
ATOM   4768  C  CA    . HIS B 1 190 ? 407.105 379.426 244.344 1.00 102.68 ? 190 HIS E CA    1 
ATOM   4769  C  C     . HIS B 1 190 ? 407.623 378.105 243.796 1.00 106.72 ? 190 HIS E C     1 
ATOM   4770  O  O     . HIS B 1 190 ? 408.401 378.087 242.835 1.00 109.15 ? 190 HIS E O     1 
ATOM   4771  C  CB    . HIS B 1 190 ? 407.886 379.829 245.592 1.00 106.63 ? 190 HIS E CB    1 
ATOM   4772  C  CG    . HIS B 1 190 ? 409.339 379.479 245.536 1.00 108.56 ? 190 HIS E CG    1 
ATOM   4773  N  ND1   . HIS B 1 190 ? 410.259 380.229 244.837 1.00 108.17 ? 190 HIS E ND1   1 
ATOM   4774  C  CD2   . HIS B 1 190 ? 410.033 378.462 246.099 1.00 106.53 ? 190 HIS E CD2   1 
ATOM   4775  C  CE1   . HIS B 1 190 ? 411.456 379.687 244.967 1.00 109.33 ? 190 HIS E CE1   1 
ATOM   4776  N  NE2   . HIS B 1 190 ? 411.346 378.613 245.728 1.00 109.89 ? 190 HIS E NE2   1 
ATOM   4777  N  N     . GLN B 1 191 ? 407.192 376.988 244.383 1.00 108.72 ? 191 GLN E N     1 
ATOM   4778  C  CA    . GLN B 1 191 ? 407.618 375.692 243.859 1.00 106.83 ? 191 GLN E CA    1 
ATOM   4779  C  C     . GLN B 1 191 ? 406.892 375.324 242.565 1.00 103.82 ? 191 GLN E C     1 
ATOM   4780  O  O     . GLN B 1 191 ? 407.477 374.668 241.696 1.00 104.06 ? 191 GLN E O     1 
ATOM   4781  C  CB    . GLN B 1 191 ? 407.410 374.605 244.910 1.00 97.69  ? 191 GLN E CB    1 
ATOM   4782  C  CG    . GLN B 1 191 ? 408.567 374.455 245.886 1.00 102.33 ? 191 GLN E CG    1 
ATOM   4783  C  CD    . GLN B 1 191 ? 409.781 373.783 245.274 1.00 110.90 ? 191 GLN E CD    1 
ATOM   4784  O  OE1   . GLN B 1 191 ? 409.772 373.405 244.102 1.00 108.44 ? 191 GLN E OE1   1 
ATOM   4785  N  NE2   . GLN B 1 191 ? 410.836 373.635 246.065 1.00 116.23 ? 191 GLN E NE2   1 
ATOM   4786  N  N     . LEU B 1 192 ? 405.630 375.734 242.412 1.00 108.45 ? 192 LEU E N     1 
ATOM   4787  C  CA    . LEU B 1 192 ? 404.838 375.317 241.257 1.00 106.64 ? 192 LEU E CA    1 
ATOM   4788  C  C     . LEU B 1 192 ? 405.199 376.066 239.982 1.00 108.46 ? 192 LEU E C     1 
ATOM   4789  O  O     . LEU B 1 192 ? 405.048 375.503 238.890 1.00 117.38 ? 192 LEU E O     1 
ATOM   4790  C  CB    . LEU B 1 192 ? 403.338 375.512 241.523 1.00 103.28 ? 192 LEU E CB    1 
ATOM   4791  C  CG    . LEU B 1 192 ? 402.470 374.417 242.167 1.00 108.95 ? 192 LEU E CG    1 
ATOM   4792  C  CD1   . LEU B 1 192 ? 403.055 373.747 243.416 1.00 117.85 ? 192 LEU E CD1   1 
ATOM   4793  C  CD2   . LEU B 1 192 ? 401.091 374.987 242.481 1.00 103.01 ? 192 LEU E CD2   1 
ATOM   4794  N  N     . VAL B 1 193 ? 405.658 377.319 240.095 1.00 109.29 ? 193 VAL E N     1 
ATOM   4795  C  CA    . VAL B 1 193 ? 405.717 378.209 238.934 1.00 108.25 ? 193 VAL E CA    1 
ATOM   4796  C  C     . VAL B 1 193 ? 406.700 377.696 237.886 1.00 110.96 ? 193 VAL E C     1 
ATOM   4797  O  O     . VAL B 1 193 ? 406.461 377.837 236.680 1.00 113.18 ? 193 VAL E O     1 
ATOM   4798  C  CB    . VAL B 1 193 ? 406.055 379.646 239.380 1.00 109.64 ? 193 VAL E CB    1 
ATOM   4799  C  CG1   . VAL B 1 193 ? 407.482 379.751 239.933 1.00 114.58 ? 193 VAL E CG1   1 
ATOM   4800  C  CG2   . VAL B 1 193 ? 405.850 380.629 238.232 1.00 108.70 ? 193 VAL E CG2   1 
ATOM   4801  N  N     . GLU B 1 194 ? 407.807 377.090 238.316 1.00 115.12 ? 194 GLU E N     1 
ATOM   4802  C  CA    . GLU B 1 194 ? 408.791 376.561 237.375 1.00 118.77 ? 194 GLU E CA    1 
ATOM   4803  C  C     . GLU B 1 194 ? 408.455 375.159 236.887 1.00 115.74 ? 194 GLU E C     1 
ATOM   4804  O  O     . GLU B 1 194 ? 408.874 374.783 235.786 1.00 115.55 ? 194 GLU E O     1 
ATOM   4805  C  CB    . GLU B 1 194 ? 410.197 376.549 237.992 1.00 119.86 ? 194 GLU E CB    1 
ATOM   4806  C  CG    . GLU B 1 194 ? 410.346 375.841 239.354 1.00 120.66 ? 194 GLU E CG    1 
ATOM   4807  C  CD    . GLU B 1 194 ? 410.202 376.757 240.570 1.00 122.33 ? 194 GLU E CD    1 
ATOM   4808  O  OE1   . GLU B 1 194 ? 410.249 377.998 240.435 1.00 123.04 ? 194 GLU E OE1   1 
ATOM   4809  O  OE2   . GLU B 1 194 ? 410.049 376.218 241.684 1.00 123.13 ? 194 GLU E OE2   1 
ATOM   4810  N  N     . ASN B 1 195 ? 407.702 374.382 237.667 1.00 103.72 ? 195 ASN E N     1 
ATOM   4811  C  CA    . ASN B 1 195 ? 407.481 372.972 237.373 1.00 101.30 ? 195 ASN E CA    1 
ATOM   4812  C  C     . ASN B 1 195 ? 406.206 372.728 236.570 1.00 106.13 ? 195 ASN E C     1 
ATOM   4813  O  O     . ASN B 1 195 ? 406.250 372.065 235.530 1.00 108.21 ? 195 ASN E O     1 
ATOM   4814  C  CB    . ASN B 1 195 ? 407.436 372.180 238.678 1.00 104.05 ? 195 ASN E CB    1 
ATOM   4815  C  CG    . ASN B 1 195 ? 408.785 372.112 239.366 1.00 108.76 ? 195 ASN E CG    1 
ATOM   4816  O  OD1   . ASN B 1 195 ? 409.728 371.515 238.848 1.00 108.87 ? 195 ASN E OD1   1 
ATOM   4817  N  ND2   . ASN B 1 195 ? 408.882 372.717 240.544 1.00 109.84 ? 195 ASN E ND2   1 
ATOM   4818  N  N     . THR B 1 196 ? 405.070 373.244 237.032 1.00 119.03 ? 196 THR E N     1 
ATOM   4819  C  CA    . THR B 1 196 ? 403.808 372.939 236.374 1.00 116.80 ? 196 THR E CA    1 
ATOM   4820  C  C     . THR B 1 196 ? 403.712 373.649 235.027 1.00 115.19 ? 196 THR E C     1 
ATOM   4821  O  O     . THR B 1 196 ? 404.404 374.636 234.764 1.00 117.61 ? 196 THR E O     1 
ATOM   4822  C  CB    . THR B 1 196 ? 402.617 373.350 237.240 1.00 117.06 ? 196 THR E CB    1 
ATOM   4823  O  OG1   . THR B 1 196 ? 402.695 374.749 237.535 1.00 123.53 ? 196 THR E OG1   1 
ATOM   4824  C  CG2   . THR B 1 196 ? 402.599 372.566 238.537 1.00 116.28 ? 196 THR E CG2   1 
ATOM   4825  N  N     . ASP B 1 197 ? 402.834 373.121 234.172 1.00 107.24 ? 197 ASP E N     1 
ATOM   4826  C  CA    . ASP B 1 197 ? 402.514 373.711 232.877 1.00 107.15 ? 197 ASP E CA    1 
ATOM   4827  C  C     . ASP B 1 197 ? 401.155 374.389 232.853 1.00 106.16 ? 197 ASP E C     1 
ATOM   4828  O  O     . ASP B 1 197 ? 400.967 375.337 232.085 1.00 107.90 ? 197 ASP E O     1 
ATOM   4829  C  CB    . ASP B 1 197 ? 402.559 372.638 231.785 1.00 108.56 ? 197 ASP E CB    1 
ATOM   4830  C  CG    . ASP B 1 197 ? 403.944 372.052 231.608 1.00 112.12 ? 197 ASP E CG    1 
ATOM   4831  O  OD1   . ASP B 1 197 ? 404.926 372.821 231.631 1.00 113.26 ? 197 ASP E OD1   1 
ATOM   4832  O  OD2   . ASP B 1 197 ? 404.056 370.820 231.459 1.00 112.76 ? 197 ASP E OD2   1 
ATOM   4833  N  N     . GLU B 1 198 ? 400.203 373.918 233.658 1.00 113.12 ? 198 GLU E N     1 
ATOM   4834  C  CA    . GLU B 1 198 ? 398.914 374.577 233.824 1.00 109.46 ? 198 GLU E CA    1 
ATOM   4835  C  C     . GLU B 1 198 ? 398.474 374.485 235.275 1.00 111.86 ? 198 GLU E C     1 
ATOM   4836  O  O     . GLU B 1 198 ? 398.657 373.453 235.926 1.00 120.30 ? 198 GLU E O     1 
ATOM   4837  C  CB    . GLU B 1 198 ? 397.825 373.982 232.919 1.00 107.67 ? 198 GLU E CB    1 
ATOM   4838  C  CG    . GLU B 1 198 ? 398.280 373.511 231.547 1.00 113.80 ? 198 GLU E CG    1 
ATOM   4839  C  CD    . GLU B 1 198 ? 397.122 373.057 230.681 1.00 118.85 ? 198 GLU E CD    1 
ATOM   4840  O  OE1   . GLU B 1 198 ? 396.354 372.174 231.111 1.00 116.06 ? 198 GLU E OE1   1 
ATOM   4841  O  OE2   . GLU B 1 198 ? 396.973 373.596 229.565 1.00 123.40 ? 198 GLU E OE2   1 
ATOM   4842  N  N     . THR B 1 199 ? 397.891 375.578 235.766 1.00 104.47 ? 199 THR E N     1 
ATOM   4843  C  CA    . THR B 1 199 ? 397.361 375.662 237.122 1.00 108.22 ? 199 THR E CA    1 
ATOM   4844  C  C     . THR B 1 199 ? 396.038 376.405 237.065 1.00 106.16 ? 199 THR E C     1 
ATOM   4845  O  O     . THR B 1 199 ? 396.002 377.572 236.662 1.00 111.67 ? 199 THR E O     1 
ATOM   4846  C  CB    . THR B 1 199 ? 398.339 376.380 238.055 1.00 114.92 ? 199 THR E CB    1 
ATOM   4847  O  OG1   . THR B 1 199 ? 399.599 375.700 238.046 1.00 120.89 ? 199 THR E OG1   1 
ATOM   4848  C  CG2   . THR B 1 199 ? 397.795 376.430 239.474 1.00 112.19 ? 199 THR E CG2   1 
ATOM   4849  N  N     . TYR B 1 200 ? 394.962 375.732 237.464 1.00 101.21 ? 200 TYR E N     1 
ATOM   4850  C  CA    . TYR B 1 200 ? 393.617 376.298 237.462 1.00 102.59 ? 200 TYR E CA    1 
ATOM   4851  C  C     . TYR B 1 200 ? 393.285 376.745 238.880 1.00 110.79 ? 200 TYR E C     1 
ATOM   4852  O  O     . TYR B 1 200 ? 393.283 375.929 239.807 1.00 114.16 ? 200 TYR E O     1 
ATOM   4853  C  CB    . TYR B 1 200 ? 392.588 375.287 236.950 1.00 103.32 ? 200 TYR E CB    1 
ATOM   4854  C  CG    . TYR B 1 200 ? 392.869 374.763 235.554 1.00 102.15 ? 200 TYR E CG    1 
ATOM   4855  C  CD1   . TYR B 1 200 ? 392.197 375.278 234.456 1.00 103.81 ? 200 TYR E CD1   1 
ATOM   4856  C  CD2   . TYR B 1 200 ? 393.779 373.735 235.337 1.00 108.20 ? 200 TYR E CD2   1 
ATOM   4857  C  CE1   . TYR B 1 200 ? 392.442 374.806 233.183 1.00 104.47 ? 200 TYR E CE1   1 
ATOM   4858  C  CE2   . TYR B 1 200 ? 394.031 373.259 234.069 1.00 110.31 ? 200 TYR E CE2   1 
ATOM   4859  C  CZ    . TYR B 1 200 ? 393.358 373.795 232.996 1.00 109.69 ? 200 TYR E CZ    1 
ATOM   4860  O  OH    . TYR B 1 200 ? 393.606 373.316 231.731 1.00 117.47 ? 200 TYR E OH    1 
ATOM   4861  N  N     . CYS B 1 201 ? 393.004 378.037 239.041 1.00 116.33 ? 201 CYS E N     1 
ATOM   4862  C  CA    . CYS B 1 201 ? 392.841 378.657 240.351 1.00 112.68 ? 201 CYS E CA    1 
ATOM   4863  C  C     . CYS B 1 201 ? 391.356 378.737 240.692 1.00 111.33 ? 201 CYS E C     1 
ATOM   4864  O  O     . CYS B 1 201 ? 390.631 379.578 240.151 1.00 109.70 ? 201 CYS E O     1 
ATOM   4865  C  CB    . CYS B 1 201 ? 393.487 380.040 240.367 1.00 116.48 ? 201 CYS E CB    1 
ATOM   4866  S  SG    . CYS B 1 201 ? 395.292 379.995 240.292 1.00 123.15 ? 201 CYS E SG    1 
ATOM   4867  N  N     . ILE B 1 202 ? 390.917 377.861 241.598 1.00 113.05 ? 202 ILE E N     1 
ATOM   4868  C  CA    . ILE B 1 202 ? 389.554 377.832 242.119 1.00 114.13 ? 202 ILE E CA    1 
ATOM   4869  C  C     . ILE B 1 202 ? 389.571 378.569 243.448 1.00 117.42 ? 202 ILE E C     1 
ATOM   4870  O  O     . ILE B 1 202 ? 390.560 378.518 244.185 1.00 118.00 ? 202 ILE E O     1 
ATOM   4871  C  CB    . ILE B 1 202 ? 389.071 376.362 242.258 1.00 116.57 ? 202 ILE E CB    1 
ATOM   4872  C  CG1   . ILE B 1 202 ? 388.468 375.799 240.952 1.00 115.43 ? 202 ILE E CG1   1 
ATOM   4873  C  CG2   . ILE B 1 202 ? 388.007 376.190 243.375 1.00 115.83 ? 202 ILE E CG2   1 
ATOM   4874  C  CD1   . ILE B 1 202 ? 387.238 376.517 240.358 1.00 115.55 ? 202 ILE E CD1   1 
ATOM   4875  N  N     . ASP B 1 203 ? 388.477 379.269 243.754 1.00 125.65 ? 203 ASP E N     1 
ATOM   4876  C  CA    . ASP B 1 203 ? 388.353 380.062 244.971 1.00 121.88 ? 203 ASP E CA    1 
ATOM   4877  C  C     . ASP B 1 203 ? 387.027 379.753 245.650 1.00 122.10 ? 203 ASP E C     1 
ATOM   4878  O  O     . ASP B 1 203 ? 385.972 379.825 245.013 1.00 130.35 ? 203 ASP E O     1 
ATOM   4879  C  CB    . ASP B 1 203 ? 388.453 381.554 244.647 1.00 125.05 ? 203 ASP E CB    1 
ATOM   4880  C  CG    . ASP B 1 203 ? 388.689 382.401 245.873 1.00 131.44 ? 203 ASP E CG    1 
ATOM   4881  O  OD1   . ASP B 1 203 ? 388.645 381.850 246.990 1.00 132.24 ? 203 ASP E OD1   1 
ATOM   4882  O  OD2   . ASP B 1 203 ? 388.908 383.620 245.718 1.00 134.23 ? 203 ASP E OD2   1 
ATOM   4883  N  N     . ASN B 1 204 ? 387.083 379.459 246.955 1.00 108.03 ? 204 ASN E N     1 
ATOM   4884  C  CA    . ASN B 1 204 ? 385.891 379.021 247.678 1.00 109.48 ? 204 ASN E CA    1 
ATOM   4885  C  C     . ASN B 1 204 ? 384.836 380.118 247.747 1.00 109.91 ? 204 ASN E C     1 
ATOM   4886  O  O     . ASN B 1 204 ? 383.638 379.844 247.592 1.00 116.70 ? 204 ASN E O     1 
ATOM   4887  C  CB    . ASN B 1 204 ? 386.271 378.571 249.089 1.00 112.42 ? 204 ASN E CB    1 
ATOM   4888  C  CG    . ASN B 1 204 ? 387.080 377.287 249.101 1.00 115.87 ? 204 ASN E CG    1 
ATOM   4889  O  OD1   . ASN B 1 204 ? 388.186 377.247 249.637 1.00 120.38 ? 204 ASN E OD1   1 
ATOM   4890  N  ND2   . ASN B 1 204 ? 386.518 376.221 248.544 1.00 110.13 ? 204 ASN E ND2   1 
ATOM   4891  N  N     . GLU B 1 205 ? 385.260 381.361 247.991 1.00 116.88 ? 205 GLU E N     1 
ATOM   4892  C  CA    . GLU B 1 205 ? 384.307 382.464 248.077 1.00 117.49 ? 205 GLU E CA    1 
ATOM   4893  C  C     . GLU B 1 205 ? 383.588 382.673 246.753 1.00 122.32 ? 205 GLU E C     1 
ATOM   4894  O  O     . GLU B 1 205 ? 382.394 382.992 246.729 1.00 124.55 ? 205 GLU E O     1 
ATOM   4895  C  CB    . GLU B 1 205 ? 385.007 383.759 248.495 1.00 120.02 ? 205 GLU E CB    1 
ATOM   4896  C  CG    . GLU B 1 205 ? 384.212 384.590 249.495 1.00 126.18 ? 205 GLU E CG    1 
ATOM   4897  C  CD    . GLU B 1 205 ? 384.983 385.785 250.027 1.00 132.84 ? 205 GLU E CD    1 
ATOM   4898  O  OE1   . GLU B 1 205 ? 386.226 385.810 249.909 1.00 132.11 ? 205 GLU E OE1   1 
ATOM   4899  O  OE2   . GLU B 1 205 ? 384.340 386.707 250.571 1.00 133.16 ? 205 GLU E OE2   1 
ATOM   4900  N  N     . ALA B 1 206 ? 384.303 382.504 245.639 1.00 113.57 ? 206 ALA E N     1 
ATOM   4901  C  CA    . ALA B 1 206 ? 383.683 382.679 244.332 1.00 107.87 ? 206 ALA E CA    1 
ATOM   4902  C  C     . ALA B 1 206 ? 382.611 381.627 244.080 1.00 109.78 ? 206 ALA E C     1 
ATOM   4903  O  O     . ALA B 1 206 ? 381.537 381.944 243.561 1.00 115.48 ? 206 ALA E O     1 
ATOM   4904  C  CB    . ALA B 1 206 ? 384.750 382.636 243.245 1.00 109.77 ? 206 ALA E CB    1 
ATOM   4905  N  N     . LEU B 1 207 ? 382.871 380.371 244.452 1.00 108.01 ? 207 LEU E N     1 
ATOM   4906  C  CA    . LEU B 1 207 ? 381.844 379.342 244.301 1.00 107.31 ? 207 LEU E CA    1 
ATOM   4907  C  C     . LEU B 1 207 ? 380.671 379.572 245.246 1.00 109.77 ? 207 LEU E C     1 
ATOM   4908  O  O     . LEU B 1 207 ? 379.523 379.292 244.882 1.00 114.95 ? 207 LEU E O     1 
ATOM   4909  C  CB    . LEU B 1 207 ? 382.420 377.937 244.500 1.00 107.87 ? 207 LEU E CB    1 
ATOM   4910  C  CG    . LEU B 1 207 ? 383.778 377.535 243.914 1.00 110.35 ? 207 LEU E CG    1 
ATOM   4911  C  CD1   . LEU B 1 207 ? 384.416 376.421 244.708 1.00 113.33 ? 207 LEU E CD1   1 
ATOM   4912  C  CD2   . LEU B 1 207 ? 383.585 377.097 242.476 1.00 114.79 ? 207 LEU E CD2   1 
ATOM   4913  N  N     . TYR B 1 208 ? 380.954 380.045 246.465 1.00 105.87 ? 208 TYR E N     1 
ATOM   4914  C  CA    . TYR B 1 208 ? 379.851 380.362 247.415 1.00 104.06 ? 208 TYR E CA    1 
ATOM   4915  C  C     . TYR B 1 208 ? 378.959 381.415 246.763 1.00 109.37 ? 208 TYR E C     1 
ATOM   4916  O  O     . TYR B 1 208 ? 377.725 381.223 246.698 1.00 115.85 ? 208 TYR E O     1 
ATOM   4917  C  CB    . TYR B 1 208 ? 380.327 380.870 248.781 1.00 105.33 ? 208 TYR E CB    1 
ATOM   4918  C  CG    . TYR B 1 208 ? 381.088 379.864 249.633 1.00 107.17 ? 208 TYR E CG    1 
ATOM   4919  C  CD1   . TYR B 1 208 ? 380.578 378.594 249.876 1.00 108.56 ? 208 TYR E CD1   1 
ATOM   4920  C  CD2   . TYR B 1 208 ? 382.296 380.202 250.231 1.00 107.00 ? 208 TYR E CD2   1 
ATOM   4921  C  CE1   . TYR B 1 208 ? 381.264 377.680 250.658 1.00 109.99 ? 208 TYR E CE1   1 
ATOM   4922  C  CE2   . TYR B 1 208 ? 382.992 379.297 251.014 1.00 107.85 ? 208 TYR E CE2   1 
ATOM   4923  C  CZ    . TYR B 1 208 ? 382.474 378.033 251.230 1.00 110.83 ? 208 TYR E CZ    1 
ATOM   4924  O  OH    . TYR B 1 208 ? 383.159 377.143 252.004 1.00 113.03 ? 208 TYR E OH    1 
ATOM   4925  N  N     . ASP B 1 209 ? 379.572 382.504 246.289 1.00 132.76 ? 209 ASP E N     1 
ATOM   4926  C  CA    . ASP B 1 209 ? 378.803 383.586 245.619 1.00 135.12 ? 209 ASP E CA    1 
ATOM   4927  C  C     . ASP B 1 209 ? 378.021 382.990 244.445 1.00 133.53 ? 209 ASP E C     1 
ATOM   4928  O  O     . ASP B 1 209 ? 376.809 383.261 244.348 1.00 133.53 ? 209 ASP E O     1 
ATOM   4929  C  CB    . ASP B 1 209 ? 379.731 384.724 245.183 1.00 139.14 ? 209 ASP E CB    1 
ATOM   4930  C  CG    . ASP B 1 209 ? 379.061 385.775 244.314 1.00 142.53 ? 209 ASP E CG    1 
ATOM   4931  O  OD1   . ASP B 1 209 ? 378.919 386.919 244.790 1.00 141.97 ? 209 ASP E OD1   1 
ATOM   4932  O  OD2   . ASP B 1 209 ? 378.720 385.455 243.157 1.00 142.76 ? 209 ASP E OD2   1 
ATOM   4933  N  N     . ILE B 1 210 ? 378.692 382.215 243.588 1.00 121.96 ? 210 ILE E N     1 
ATOM   4934  C  CA    . ILE B 1 210 ? 378.027 381.667 242.407 1.00 119.89 ? 210 ILE E CA    1 
ATOM   4935  C  C     . ILE B 1 210 ? 376.787 380.886 242.822 1.00 119.70 ? 210 ILE E C     1 
ATOM   4936  O  O     . ILE B 1 210 ? 375.713 381.025 242.223 1.00 123.49 ? 210 ILE E O     1 
ATOM   4937  C  CB    . ILE B 1 210 ? 379.012 380.802 241.595 1.00 118.29 ? 210 ILE E CB    1 
ATOM   4938  C  CG1   . ILE B 1 210 ? 379.943 381.711 240.791 1.00 121.31 ? 210 ILE E CG1   1 
ATOM   4939  C  CG2   . ILE B 1 210 ? 378.292 379.848 240.633 1.00 115.41 ? 210 ILE E CG2   1 
ATOM   4940  C  CD1   . ILE B 1 210 ? 381.277 381.090 240.453 1.00 119.62 ? 210 ILE E CD1   1 
ATOM   4941  N  N     . CYS B 1 211 ? 376.921 380.056 243.861 1.00 119.54 ? 211 CYS E N     1 
ATOM   4942  C  CA    . CYS B 1 211 ? 375.787 379.282 244.353 1.00 118.65 ? 211 CYS E CA    1 
ATOM   4943  C  C     . CYS B 1 211 ? 374.679 380.198 244.854 1.00 118.21 ? 211 CYS E C     1 
ATOM   4944  O  O     . CYS B 1 211 ? 373.490 379.915 244.667 1.00 121.07 ? 211 CYS E O     1 
ATOM   4945  C  CB    . CYS B 1 211 ? 376.238 378.334 245.465 1.00 115.45 ? 211 CYS E CB    1 
ATOM   4946  S  SG    . CYS B 1 211 ? 377.128 376.871 244.893 1.00 119.51 ? 211 CYS E SG    1 
ATOM   4947  N  N     . PHE B 1 212 ? 375.052 381.304 245.498 1.00 131.09 ? 212 PHE E N     1 
ATOM   4948  C  CA    . PHE B 1 212 ? 374.040 382.221 246.012 1.00 129.89 ? 212 PHE E CA    1 
ATOM   4949  C  C     . PHE B 1 212 ? 373.347 382.990 244.890 1.00 131.83 ? 212 PHE E C     1 
ATOM   4950  O  O     . PHE B 1 212 ? 372.115 383.089 244.870 1.00 133.03 ? 212 PHE E O     1 
ATOM   4951  C  CB    . PHE B 1 212 ? 374.676 383.182 247.009 1.00 133.11 ? 212 PHE E CB    1 
ATOM   4952  C  CG    . PHE B 1 212 ? 373.696 384.102 247.671 1.00 135.17 ? 212 PHE E CG    1 
ATOM   4953  C  CD1   . PHE B 1 212 ? 372.948 383.670 248.751 1.00 134.16 ? 212 PHE E CD1   1 
ATOM   4954  C  CD2   . PHE B 1 212 ? 373.535 385.402 247.227 1.00 134.94 ? 212 PHE E CD2   1 
ATOM   4955  C  CE1   . PHE B 1 212 ? 372.048 384.511 249.368 1.00 135.55 ? 212 PHE E CE1   1 
ATOM   4956  C  CE2   . PHE B 1 212 ? 372.636 386.249 247.840 1.00 135.04 ? 212 PHE E CE2   1 
ATOM   4957  C  CZ    . PHE B 1 212 ? 371.892 385.803 248.913 1.00 136.29 ? 212 PHE E CZ    1 
ATOM   4958  N  N     . ARG B 1 213 ? 374.116 383.538 243.946 1.00 138.26 ? 213 ARG E N     1 
ATOM   4959  C  CA    . ARG B 1 213 ? 373.538 384.420 242.933 1.00 138.47 ? 213 ARG E CA    1 
ATOM   4960  C  C     . ARG B 1 213 ? 372.810 383.639 241.846 1.00 136.86 ? 213 ARG E C     1 
ATOM   4961  O  O     . ARG B 1 213 ? 371.656 383.942 241.527 1.00 138.63 ? 213 ARG E O     1 
ATOM   4962  C  CB    . ARG B 1 213 ? 374.619 385.316 242.303 1.00 141.39 ? 213 ARG E CB    1 
ATOM   4963  C  CG    . ARG B 1 213 ? 374.717 386.746 242.884 1.00 141.25 ? 213 ARG E CG    1 
ATOM   4964  C  CD    . ARG B 1 213 ? 375.216 387.764 241.848 1.00 141.76 ? 213 ARG E CD    1 
ATOM   4965  N  NE    . ARG B 1 213 ? 376.609 387.548 241.458 1.00 142.10 ? 213 ARG E NE    1 
ATOM   4966  C  CZ    . ARG B 1 213 ? 377.674 388.120 242.013 1.00 143.00 ? 213 ARG E CZ    1 
ATOM   4967  N  NH1   . ARG B 1 213 ? 377.573 388.997 243.003 1.00 143.26 ? 213 ARG E NH1   1 
ATOM   4968  N  NH2   . ARG B 1 213 ? 378.886 387.795 241.570 1.00 142.92 ? 213 ARG E NH2   1 
ATOM   4969  N  N     . THR B 1 214 ? 373.466 382.636 241.261 1.00 129.57 ? 214 THR E N     1 
ATOM   4970  C  CA    . THR B 1 214 ? 372.916 381.967 240.087 1.00 131.10 ? 214 THR E CA    1 
ATOM   4971  C  C     . THR B 1 214 ? 372.059 380.768 240.486 1.00 130.44 ? 214 THR E C     1 
ATOM   4972  O  O     . THR B 1 214 ? 370.897 380.674 240.079 1.00 133.91 ? 214 THR E O     1 
ATOM   4973  C  CB    . THR B 1 214 ? 374.058 381.545 239.154 1.00 130.29 ? 214 THR E CB    1 
ATOM   4974  O  OG1   . THR B 1 214 ? 374.930 382.664 238.954 1.00 130.73 ? 214 THR E OG1   1 
ATOM   4975  C  CG2   . THR B 1 214 ? 373.540 381.132 237.768 1.00 134.52 ? 214 THR E CG2   1 
ATOM   4976  N  N     . LEU B 1 215 ? 372.610 379.851 241.283 1.00 127.17 ? 215 LEU E N     1 
ATOM   4977  C  CA    . LEU B 1 215 ? 371.881 378.644 241.654 1.00 130.29 ? 215 LEU E CA    1 
ATOM   4978  C  C     . LEU B 1 215 ? 370.868 378.865 242.773 1.00 131.16 ? 215 LEU E C     1 
ATOM   4979  O  O     . LEU B 1 215 ? 369.976 378.028 242.942 1.00 132.96 ? 215 LEU E O     1 
ATOM   4980  C  CB    . LEU B 1 215 ? 372.859 377.544 242.073 1.00 127.99 ? 215 LEU E CB    1 
ATOM   4981  C  CG    . LEU B 1 215 ? 373.776 376.984 240.986 1.00 127.26 ? 215 LEU E CG    1 
ATOM   4982  C  CD1   . LEU B 1 215 ? 374.972 376.299 241.610 1.00 128.65 ? 215 LEU E CD1   1 
ATOM   4983  C  CD2   . LEU B 1 215 ? 373.017 375.996 240.112 1.00 129.86 ? 215 LEU E CD2   1 
ATOM   4984  N  N     . LYS B 1 216 ? 370.977 379.958 243.535 1.00 139.96 ? 216 LYS E N     1 
ATOM   4985  C  CA    . LYS B 1 216 ? 370.013 380.287 244.590 1.00 138.52 ? 216 LYS E CA    1 
ATOM   4986  C  C     . LYS B 1 216 ? 369.953 379.214 245.677 1.00 137.70 ? 216 LYS E C     1 
ATOM   4987  O  O     . LYS B 1 216 ? 368.923 379.049 246.335 1.00 139.32 ? 216 LYS E O     1 
ATOM   4988  C  CB    . LYS B 1 216 ? 368.609 380.513 244.014 1.00 139.39 ? 216 LYS E CB    1 
ATOM   4989  C  CG    . LYS B 1 216 ? 368.545 381.364 242.734 1.00 140.73 ? 216 LYS E CG    1 
ATOM   4990  C  CD    . LYS B 1 216 ? 369.143 382.760 242.871 1.00 143.54 ? 216 LYS E CD    1 
ATOM   4991  C  CE    . LYS B 1 216 ? 368.569 383.550 244.034 1.00 143.45 ? 216 LYS E CE    1 
ATOM   4992  N  NZ    . LYS B 1 216 ? 368.513 385.005 243.728 1.00 144.30 ? 216 LYS E NZ    1 
ATOM   4993  N  N     . LEU B 1 217 ? 371.043 378.479 245.890 1.00 124.49 ? 217 LEU E N     1 
ATOM   4994  C  CA    . LEU B 1 217 ? 371.051 377.424 246.894 1.00 124.90 ? 217 LEU E CA    1 
ATOM   4995  C  C     . LEU B 1 217 ? 371.159 378.030 248.287 1.00 127.89 ? 217 LEU E C     1 
ATOM   4996  O  O     . LEU B 1 217 ? 372.051 378.840 248.556 1.00 130.31 ? 217 LEU E O     1 
ATOM   4997  C  CB    . LEU B 1 217 ? 372.203 376.450 246.650 1.00 123.51 ? 217 LEU E CB    1 
ATOM   4998  C  CG    . LEU B 1 217 ? 372.121 375.623 245.365 1.00 125.42 ? 217 LEU E CG    1 
ATOM   4999  C  CD1   . LEU B 1 217 ? 373.457 374.962 245.067 1.00 126.98 ? 217 LEU E CD1   1 
ATOM   5000  C  CD2   . LEU B 1 217 ? 371.014 374.577 245.447 1.00 124.85 ? 217 LEU E CD2   1 
ATOM   5001  N  N     . THR B 1 218 ? 370.245 377.631 249.171 1.00 127.04 ? 218 THR E N     1 
ATOM   5002  C  CA    . THR B 1 218 ? 370.226 378.175 250.523 1.00 124.99 ? 218 THR E CA    1 
ATOM   5003  C  C     . THR B 1 218 ? 371.338 377.589 251.384 1.00 123.47 ? 218 THR E C     1 
ATOM   5004  O  O     . THR B 1 218 ? 371.930 378.305 252.200 1.00 127.44 ? 218 THR E O     1 
ATOM   5005  C  CB    . THR B 1 218 ? 368.868 377.912 251.176 1.00 127.17 ? 218 THR E CB    1 
ATOM   5006  O  OG1   . THR B 1 218 ? 368.699 376.504 251.382 1.00 125.41 ? 218 THR E OG1   1 
ATOM   5007  C  CG2   . THR B 1 218 ? 367.737 378.437 250.301 1.00 127.77 ? 218 THR E CG2   1 
ATOM   5008  N  N     . THR B 1 219 ? 371.632 376.299 251.214 1.00 113.90 ? 219 THR E N     1 
ATOM   5009  C  CA    . THR B 1 219 ? 372.610 375.573 252.028 1.00 118.13 ? 219 THR E CA    1 
ATOM   5010  C  C     . THR B 1 219 ? 373.577 374.825 251.119 1.00 113.17 ? 219 THR E C     1 
ATOM   5011  O  O     . THR B 1 219 ? 373.530 373.592 251.025 1.00 110.95 ? 219 THR E O     1 
ATOM   5012  C  CB    . THR B 1 219 ? 371.907 374.601 252.976 1.00 117.72 ? 219 THR E CB    1 
ATOM   5013  O  OG1   . THR B 1 219 ? 371.045 373.738 252.224 1.00 112.93 ? 219 THR E OG1   1 
ATOM   5014  C  CG2   . THR B 1 219 ? 371.086 375.358 254.008 1.00 118.24 ? 219 THR E CG2   1 
ATOM   5015  N  N     . PRO B 1 220 ? 374.478 375.540 250.431 1.00 106.75 ? 220 PRO E N     1 
ATOM   5016  C  CA    . PRO B 1 220 ? 375.486 374.860 249.606 1.00 110.06 ? 220 PRO E CA    1 
ATOM   5017  C  C     . PRO B 1 220 ? 376.610 374.307 250.467 1.00 110.94 ? 220 PRO E C     1 
ATOM   5018  O  O     . PRO B 1 220 ? 377.443 375.057 250.986 1.00 115.24 ? 220 PRO E O     1 
ATOM   5019  C  CB    . PRO B 1 220 ? 375.977 375.972 248.669 1.00 113.15 ? 220 PRO E CB    1 
ATOM   5020  C  CG    . PRO B 1 220 ? 375.709 377.233 249.383 1.00 111.70 ? 220 PRO E CG    1 
ATOM   5021  C  CD    . PRO B 1 220 ? 374.554 377.006 250.305 1.00 109.58 ? 220 PRO E CD    1 
ATOM   5022  N  N     . THR B 1 221 ? 376.636 372.987 250.621 1.00 102.54 ? 221 THR E N     1 
ATOM   5023  C  CA    . THR B 1 221 ? 377.739 372.327 251.300 1.00 105.00 ? 221 THR E CA    1 
ATOM   5024  C  C     . THR B 1 221 ? 378.945 372.270 250.368 1.00 109.19 ? 221 THR E C     1 
ATOM   5025  O  O     . THR B 1 221 ? 378.900 372.730 249.224 1.00 109.08 ? 221 THR E O     1 
ATOM   5026  C  CB    . THR B 1 221 ? 377.334 370.924 251.746 1.00 102.53 ? 221 THR E CB    1 
ATOM   5027  O  OG1   . THR B 1 221 ? 377.133 370.094 250.596 1.00 105.09 ? 221 THR E OG1   1 
ATOM   5028  C  CG2   . THR B 1 221 ? 376.055 370.965 252.570 1.00 102.34 ? 221 THR E CG2   1 
ATOM   5029  N  N     . TYR B 1 222 ? 380.039 371.676 250.849 1.00 101.11 ? 222 TYR E N     1 
ATOM   5030  C  CA    . TYR B 1 222 ? 381.202 371.468 249.993 1.00 96.21  ? 222 TYR E CA    1 
ATOM   5031  C  C     . TYR B 1 222 ? 380.922 370.501 248.850 1.00 96.42  ? 222 TYR E C     1 
ATOM   5032  O  O     . TYR B 1 222 ? 381.677 370.491 247.870 1.00 101.48 ? 222 TYR E O     1 
ATOM   5033  C  CB    . TYR B 1 222 ? 382.390 370.945 250.812 1.00 94.01  ? 222 TYR E CB    1 
ATOM   5034  C  CG    . TYR B 1 222 ? 383.234 371.997 251.512 1.00 96.41  ? 222 TYR E CG    1 
ATOM   5035  C  CD1   . TYR B 1 222 ? 383.850 373.023 250.805 1.00 99.32  ? 222 TYR E CD1   1 
ATOM   5036  C  CD2   . TYR B 1 222 ? 383.422 371.952 252.884 1.00 98.22  ? 222 TYR E CD2   1 
ATOM   5037  C  CE1   . TYR B 1 222 ? 384.619 373.971 251.444 1.00 99.82  ? 222 TYR E CE1   1 
ATOM   5038  C  CE2   . TYR B 1 222 ? 384.190 372.898 253.532 1.00 97.22  ? 222 TYR E CE2   1 
ATOM   5039  C  CZ    . TYR B 1 222 ? 384.786 373.904 252.806 1.00 98.23  ? 222 TYR E CZ    1 
ATOM   5040  O  OH    . TYR B 1 222 ? 385.552 374.849 253.446 1.00 99.13  ? 222 TYR E OH    1 
ATOM   5041  N  N     . GLY B 1 223 ? 379.871 369.683 248.956 1.00 88.53  ? 223 GLY E N     1 
ATOM   5042  C  CA    . GLY B 1 223 ? 379.521 368.800 247.859 1.00 95.48  ? 223 GLY E CA    1 
ATOM   5043  C  C     . GLY B 1 223 ? 379.181 369.550 246.587 1.00 101.22 ? 223 GLY E C     1 
ATOM   5044  O  O     . GLY B 1 223 ? 379.593 369.153 245.498 1.00 102.97 ? 223 GLY E O     1 
ATOM   5045  N  N     . ASP B 1 224 ? 378.451 370.659 246.707 1.00 110.84 ? 224 ASP E N     1 
ATOM   5046  C  CA    . ASP B 1 224 ? 378.093 371.437 245.523 1.00 112.23 ? 224 ASP E CA    1 
ATOM   5047  C  C     . ASP B 1 224 ? 379.316 372.116 244.915 1.00 113.48 ? 224 ASP E C     1 
ATOM   5048  O  O     . ASP B 1 224 ? 379.450 372.193 243.685 1.00 115.22 ? 224 ASP E O     1 
ATOM   5049  C  CB    . ASP B 1 224 ? 377.027 372.469 245.881 1.00 113.00 ? 224 ASP E CB    1 
ATOM   5050  C  CG    . ASP B 1 224 ? 375.828 371.852 246.574 1.00 114.89 ? 224 ASP E CG    1 
ATOM   5051  O  OD1   . ASP B 1 224 ? 374.935 371.331 245.874 1.00 113.64 ? 224 ASP E OD1   1 
ATOM   5052  O  OD2   . ASP B 1 224 ? 375.780 371.885 247.821 1.00 117.60 ? 224 ASP E OD2   1 
ATOM   5053  N  N     . LEU B 1 225 ? 380.212 372.624 245.763 1.00 106.15 ? 225 LEU E N     1 
ATOM   5054  C  CA    . LEU B 1 225 ? 381.444 373.237 245.276 1.00 104.68 ? 225 LEU E CA    1 
ATOM   5055  C  C     . LEU B 1 225 ? 382.294 372.220 244.524 1.00 106.12 ? 225 LEU E C     1 
ATOM   5056  O  O     . LEU B 1 225 ? 382.809 372.498 243.430 1.00 109.43 ? 225 LEU E O     1 
ATOM   5057  C  CB    . LEU B 1 225 ? 382.228 373.821 246.453 1.00 104.84 ? 225 LEU E CB    1 
ATOM   5058  C  CG    . LEU B 1 225 ? 381.783 375.191 246.980 1.00 105.38 ? 225 LEU E CG    1 
ATOM   5059  C  CD1   . LEU B 1 225 ? 380.480 375.103 247.752 1.00 104.98 ? 225 LEU E CD1   1 
ATOM   5060  C  CD2   . LEU B 1 225 ? 382.850 375.821 247.871 1.00 108.52 ? 225 LEU E CD2   1 
ATOM   5061  N  N     . ASN B 1 226 ? 382.439 371.025 245.096 1.00 91.65  ? 226 ASN E N     1 
ATOM   5062  C  CA    . ASN B 1 226 ? 383.157 369.963 244.409 1.00 93.86  ? 226 ASN E CA    1 
ATOM   5063  C  C     . ASN B 1 226 ? 382.431 369.536 243.141 1.00 99.30  ? 226 ASN E C     1 
ATOM   5064  O  O     . ASN B 1 226 ? 383.077 369.140 242.167 1.00 108.75 ? 226 ASN E O     1 
ATOM   5065  C  CB    . ASN B 1 226 ? 383.348 368.778 245.351 1.00 95.05  ? 226 ASN E CB    1 
ATOM   5066  C  CG    . ASN B 1 226 ? 384.129 369.150 246.594 1.00 93.61  ? 226 ASN E CG    1 
ATOM   5067  O  OD1   . ASN B 1 226 ? 384.659 370.255 246.698 1.00 93.73  ? 226 ASN E OD1   1 
ATOM   5068  N  ND2   . ASN B 1 226 ? 384.202 368.230 247.547 1.00 96.95  ? 226 ASN E ND2   1 
ATOM   5069  N  N     . HIS B 1 227 ? 381.098 369.625 243.131 1.00 101.72 ? 227 HIS E N     1 
ATOM   5070  C  CA    . HIS B 1 227 ? 380.334 369.341 241.920 1.00 103.84 ? 227 HIS E CA    1 
ATOM   5071  C  C     . HIS B 1 227 ? 380.713 370.306 240.804 1.00 102.70 ? 227 HIS E C     1 
ATOM   5072  O  O     . HIS B 1 227 ? 380.940 369.896 239.662 1.00 106.18 ? 227 HIS E O     1 
ATOM   5073  C  CB    . HIS B 1 227 ? 378.835 369.427 242.215 1.00 106.38 ? 227 HIS E CB    1 
ATOM   5074  C  CG    . HIS B 1 227 ? 378.000 368.517 241.372 1.00 109.37 ? 227 HIS E CG    1 
ATOM   5075  N  ND1   . HIS B 1 227 ? 378.173 368.395 240.010 1.00 106.50 ? 227 HIS E ND1   1 
ATOM   5076  C  CD2   . HIS B 1 227 ? 376.984 367.683 241.698 1.00 110.16 ? 227 HIS E CD2   1 
ATOM   5077  C  CE1   . HIS B 1 227 ? 377.300 367.526 239.534 1.00 109.98 ? 227 HIS E CE1   1 
ATOM   5078  N  NE2   . HIS B 1 227 ? 376.566 367.079 240.537 1.00 113.98 ? 227 HIS E NE2   1 
ATOM   5079  N  N     . LEU B 1 228 ? 380.805 371.597 241.129 1.00 101.28 ? 228 LEU E N     1 
ATOM   5080  C  CA    . LEU B 1 228 ? 381.182 372.592 240.123 1.00 107.07 ? 228 LEU E CA    1 
ATOM   5081  C  C     . LEU B 1 228 ? 382.615 372.384 239.637 1.00 108.32 ? 228 LEU E C     1 
ATOM   5082  O  O     . LEU B 1 228 ? 382.901 372.495 238.434 1.00 108.37 ? 228 LEU E O     1 
ATOM   5083  C  CB    . LEU B 1 228 ? 381.014 374.005 240.686 1.00 104.01 ? 228 LEU E CB    1 
ATOM   5084  C  CG    . LEU B 1 228 ? 379.684 374.695 240.376 1.00 102.44 ? 228 LEU E CG    1 
ATOM   5085  C  CD1   . LEU B 1 228 ? 378.509 373.962 241.008 1.00 106.89 ? 228 LEU E CD1   1 
ATOM   5086  C  CD2   . LEU B 1 228 ? 379.725 376.135 240.848 1.00 105.30 ? 228 LEU E CD2   1 
ATOM   5087  N  N     . VAL B 1 229 ? 383.534 372.096 240.559 1.00 103.05 ? 229 VAL E N     1 
ATOM   5088  C  CA    . VAL B 1 229 ? 384.928 371.903 240.163 1.00 97.99  ? 229 VAL E CA    1 
ATOM   5089  C  C     . VAL B 1 229 ? 385.060 370.664 239.283 1.00 99.88  ? 229 VAL E C     1 
ATOM   5090  O  O     . VAL B 1 229 ? 385.778 370.668 238.272 1.00 106.87 ? 229 VAL E O     1 
ATOM   5091  C  CB    . VAL B 1 229 ? 385.828 371.826 241.410 1.00 99.62  ? 229 VAL E CB    1 
ATOM   5092  C  CG1   . VAL B 1 229 ? 387.245 371.392 241.035 1.00 99.75  ? 229 VAL E CG1   1 
ATOM   5093  C  CG2   . VAL B 1 229 ? 385.844 373.174 242.127 1.00 102.97 ? 229 VAL E CG2   1 
ATOM   5094  N  N     . SER B 1 230 ? 384.357 369.589 239.641 1.00 97.02  ? 230 SER E N     1 
ATOM   5095  C  CA    . SER B 1 230 ? 384.339 368.394 238.811 1.00 101.85 ? 230 SER E CA    1 
ATOM   5096  C  C     . SER B 1 230 ? 383.693 368.662 237.461 1.00 105.75 ? 230 SER E C     1 
ATOM   5097  O  O     . SER B 1 230 ? 384.075 368.046 236.459 1.00 106.10 ? 230 SER E O     1 
ATOM   5098  C  CB    . SER B 1 230 ? 383.594 367.281 239.537 1.00 104.50 ? 230 SER E CB    1 
ATOM   5099  O  OG    . SER B 1 230 ? 382.418 367.782 240.141 1.00 110.52 ? 230 SER E OG    1 
ATOM   5100  N  N     . ALA B 1 231 ? 382.700 369.554 237.421 1.00 108.72 ? 231 ALA E N     1 
ATOM   5101  C  CA    . ALA B 1 231 ? 382.107 369.949 236.152 1.00 109.10 ? 231 ALA E CA    1 
ATOM   5102  C  C     . ALA B 1 231 ? 383.145 370.582 235.243 1.00 105.27 ? 231 ALA E C     1 
ATOM   5103  O  O     . ALA B 1 231 ? 383.240 370.236 234.059 1.00 105.26 ? 231 ALA E O     1 
ATOM   5104  C  CB    . ALA B 1 231 ? 380.956 370.922 236.399 1.00 110.98 ? 231 ALA E CB    1 
ATOM   5105  N  N     . THR B 1 232 ? 383.951 371.493 235.791 1.00 98.33  ? 232 THR E N     1 
ATOM   5106  C  CA    . THR B 1 232 ? 385.009 372.104 234.990 1.00 98.48  ? 232 THR E CA    1 
ATOM   5107  C  C     . THR B 1 232 ? 386.037 371.065 234.547 1.00 100.80 ? 232 THR E C     1 
ATOM   5108  O  O     . THR B 1 232 ? 386.554 371.131 233.424 1.00 105.63 ? 232 THR E O     1 
ATOM   5109  C  CB    . THR B 1 232 ? 385.689 373.225 235.771 1.00 98.67  ? 232 THR E CB    1 
ATOM   5110  O  OG1   . THR B 1 232 ? 384.753 374.283 235.997 1.00 99.08  ? 232 THR E OG1   1 
ATOM   5111  C  CG2   . THR B 1 232 ? 386.876 373.783 234.988 1.00 96.79  ? 232 THR E CG2   1 
ATOM   5112  N  N     . MET B 1 233 ? 386.356 370.110 235.423 1.00 106.39 ? 233 MET E N     1 
ATOM   5113  C  CA    . MET B 1 233 ? 387.330 369.076 235.077 1.00 104.25 ? 233 MET E CA    1 
ATOM   5114  C  C     . MET B 1 233 ? 386.842 368.220 233.912 1.00 109.55 ? 233 MET E C     1 
ATOM   5115  O  O     . MET B 1 233 ? 387.566 368.003 232.926 1.00 112.28 ? 233 MET E O     1 
ATOM   5116  C  CB    . MET B 1 233 ? 387.603 368.200 236.293 1.00 101.44 ? 233 MET E CB    1 
ATOM   5117  C  CG    . MET B 1 233 ? 388.626 368.776 237.226 1.00 103.46 ? 233 MET E CG    1 
ATOM   5118  S  SD    . MET B 1 233 ? 388.223 368.404 238.931 1.00 128.49 ? 233 MET E SD    1 
ATOM   5119  C  CE    . MET B 1 233 ? 389.857 368.468 239.625 1.00 112.84 ? 233 MET E CE    1 
ATOM   5120  N  N     . SER B 1 234 ? 385.610 367.716 234.019 1.00 108.93 ? 234 SER E N     1 
ATOM   5121  C  CA    . SER B 1 234 ? 385.023 366.935 232.939 1.00 109.85 ? 234 SER E CA    1 
ATOM   5122  C  C     . SER B 1 234 ? 384.900 367.760 231.668 1.00 110.87 ? 234 SER E C     1 
ATOM   5123  O  O     . SER B 1 234 ? 385.035 367.220 230.565 1.00 115.77 ? 234 SER E O     1 
ATOM   5124  C  CB    . SER B 1 234 ? 383.653 366.404 233.362 1.00 109.94 ? 234 SER E CB    1 
ATOM   5125  O  OG    . SER B 1 234 ? 382.891 365.994 232.240 1.00 115.99 ? 234 SER E OG    1 
ATOM   5126  N  N     . GLY B 1 235 ? 384.653 369.064 231.800 1.00 95.74  ? 235 GLY E N     1 
ATOM   5127  C  CA    . GLY B 1 235 ? 384.601 369.912 230.624 1.00 95.69  ? 235 GLY E CA    1 
ATOM   5128  C  C     . GLY B 1 235 ? 385.939 370.025 229.917 1.00 97.24  ? 235 GLY E C     1 
ATOM   5129  O  O     . GLY B 1 235 ? 386.012 369.906 228.691 1.00 97.41  ? 235 GLY E O     1 
ATOM   5130  N  N     . VAL B 1 236 ? 387.016 370.263 230.672 1.00 98.67  ? 236 VAL E N     1 
ATOM   5131  C  CA    . VAL B 1 236 ? 388.308 370.474 230.020 1.00 94.45  ? 236 VAL E CA    1 
ATOM   5132  C  C     . VAL B 1 236 ? 388.824 369.176 229.412 1.00 93.66  ? 236 VAL E C     1 
ATOM   5133  O  O     . VAL B 1 236 ? 389.386 369.185 228.310 1.00 93.99  ? 236 VAL E O     1 
ATOM   5134  C  CB    . VAL B 1 236 ? 389.354 371.099 230.970 1.00 86.54  ? 236 VAL E CB    1 
ATOM   5135  C  CG1   . VAL B 1 236 ? 388.939 372.484 231.388 1.00 91.15  ? 236 VAL E CG1   1 
ATOM   5136  C  CG2   . VAL B 1 236 ? 389.638 370.250 232.199 1.00 98.29  ? 236 VAL E CG2   1 
ATOM   5137  N  N     . THR B 1 237 ? 388.639 368.044 230.100 1.00 106.76 ? 237 THR E N     1 
ATOM   5138  C  CA    . THR B 1 237 ? 389.174 366.775 229.615 1.00 105.86 ? 237 THR E CA    1 
ATOM   5139  C  C     . THR B 1 237 ? 388.193 366.020 228.716 1.00 105.91 ? 237 THR E C     1 
ATOM   5140  O  O     . THR B 1 237 ? 388.359 364.813 228.513 1.00 110.16 ? 237 THR E O     1 
ATOM   5141  C  CB    . THR B 1 237 ? 389.593 365.886 230.790 1.00 110.25 ? 237 THR E CB    1 
ATOM   5142  O  OG1   . THR B 1 237 ? 390.618 366.538 231.549 1.00 112.37 ? 237 THR E OG1   1 
ATOM   5143  C  CG2   . THR B 1 237 ? 390.137 364.549 230.274 1.00 110.82 ? 237 THR E CG2   1 
ATOM   5144  N  N     . THR B 1 238 ? 387.184 366.697 228.165 1.00 105.94 ? 238 THR E N     1 
ATOM   5145  C  CA    . THR B 1 238 ? 386.187 366.007 227.352 1.00 110.71 ? 238 THR E CA    1 
ATOM   5146  C  C     . THR B 1 238 ? 386.709 365.630 225.971 1.00 110.95 ? 238 THR E C     1 
ATOM   5147  O  O     . THR B 1 238 ? 386.226 364.658 225.379 1.00 113.73 ? 238 THR E O     1 
ATOM   5148  C  CB    . THR B 1 238 ? 384.932 366.870 227.202 1.00 115.99 ? 238 THR E CB    1 
ATOM   5149  O  OG1   . THR B 1 238 ? 383.886 366.092 226.609 1.00 118.75 ? 238 THR E OG1   1 
ATOM   5150  C  CG2   . THR B 1 238 ? 385.201 368.096 226.330 1.00 110.41 ? 238 THR E CG2   1 
ATOM   5151  N  N     . CYS B 1 239 ? 387.679 366.374 225.438 1.00 105.07 ? 239 CYS E N     1 
ATOM   5152  C  CA    . CYS B 1 239 ? 388.098 366.155 224.059 1.00 106.10 ? 239 CYS E CA    1 
ATOM   5153  C  C     . CYS B 1 239 ? 388.850 364.841 223.895 1.00 109.51 ? 239 CYS E C     1 
ATOM   5154  O  O     . CYS B 1 239 ? 388.771 364.214 222.833 1.00 106.76 ? 239 CYS E O     1 
ATOM   5155  C  CB    . CYS B 1 239 ? 388.950 367.330 223.591 1.00 108.75 ? 239 CYS E CB    1 
ATOM   5156  S  SG    . CYS B 1 239 ? 388.054 368.895 223.630 1.00 114.90 ? 239 CYS E SG    1 
ATOM   5157  N  N     . LEU B 1 240 ? 389.584 364.410 224.921 1.00 109.54 ? 240 LEU E N     1 
ATOM   5158  C  CA    . LEU B 1 240 ? 390.193 363.087 224.900 1.00 107.20 ? 240 LEU E CA    1 
ATOM   5159  C  C     . LEU B 1 240 ? 389.182 361.965 225.093 1.00 108.13 ? 240 LEU E C     1 
ATOM   5160  O  O     . LEU B 1 240 ? 389.462 360.833 224.687 1.00 110.23 ? 240 LEU E O     1 
ATOM   5161  C  CB    . LEU B 1 240 ? 391.256 362.974 225.993 1.00 105.18 ? 240 LEU E CB    1 
ATOM   5162  C  CG    . LEU B 1 240 ? 392.280 364.098 226.124 1.00 103.88 ? 240 LEU E CG    1 
ATOM   5163  C  CD1   . LEU B 1 240 ? 393.262 363.759 227.222 1.00 104.08 ? 240 LEU E CD1   1 
ATOM   5164  C  CD2   . LEU B 1 240 ? 393.008 364.316 224.819 1.00 107.28 ? 240 LEU E CD2   1 
ATOM   5165  N  N     . ARG B 1 241 ? 388.019 362.252 225.682 1.00 102.92 ? 241 ARG E N     1 
ATOM   5166  C  CA    . ARG B 1 241 ? 387.094 361.226 226.138 1.00 105.60 ? 241 ARG E CA    1 
ATOM   5167  C  C     . ARG B 1 241 ? 385.930 360.967 225.196 1.00 103.48 ? 241 ARG E C     1 
ATOM   5168  O  O     . ARG B 1 241 ? 385.242 359.957 225.371 1.00 103.37 ? 241 ARG E O     1 
ATOM   5169  C  CB    . ARG B 1 241 ? 386.514 361.618 227.503 1.00 107.53 ? 241 ARG E CB    1 
ATOM   5170  C  CG    . ARG B 1 241 ? 387.487 361.506 228.670 1.00 104.64 ? 241 ARG E CG    1 
ATOM   5171  C  CD    . ARG B 1 241 ? 386.758 361.317 229.994 1.00 106.76 ? 241 ARG E CD    1 
ATOM   5172  N  NE    . ARG B 1 241 ? 385.523 362.094 230.065 1.00 97.47  ? 241 ARG E NE    1 
ATOM   5173  C  CZ    . ARG B 1 241 ? 385.439 363.392 230.334 1.00 98.36  ? 241 ARG E CZ    1 
ATOM   5174  N  NH1   . ARG B 1 241 ? 386.510 364.127 230.589 1.00 100.96 ? 241 ARG E NH1   1 
ATOM   5175  N  NH2   . ARG B 1 241 ? 384.244 363.972 230.346 1.00 105.72 ? 241 ARG E NH2   1 
ATOM   5176  N  N     . PHE B 1 242 ? 385.664 361.856 224.247 1.00 102.50 ? 242 PHE E N     1 
ATOM   5177  C  CA    . PHE B 1 242 ? 384.536 361.740 223.338 1.00 106.83 ? 242 PHE E CA    1 
ATOM   5178  C  C     . PHE B 1 242 ? 384.940 362.305 221.985 1.00 106.04 ? 242 PHE E C     1 
ATOM   5179  O  O     . PHE B 1 242 ? 385.877 363.106 221.902 1.00 107.10 ? 242 PHE E O     1 
ATOM   5180  C  CB    . PHE B 1 242 ? 383.309 362.493 223.873 1.00 105.27 ? 242 PHE E CB    1 
ATOM   5181  C  CG    . PHE B 1 242 ? 382.741 361.919 225.143 1.00 106.86 ? 242 PHE E CG    1 
ATOM   5182  C  CD1   . PHE B 1 242 ? 382.180 360.653 225.161 1.00 108.53 ? 242 PHE E CD1   1 
ATOM   5183  C  CD2   . PHE B 1 242 ? 382.773 362.647 226.319 1.00 107.54 ? 242 PHE E CD2   1 
ATOM   5184  C  CE1   . PHE B 1 242 ? 381.659 360.128 226.328 1.00 109.75 ? 242 PHE E CE1   1 
ATOM   5185  C  CE2   . PHE B 1 242 ? 382.255 362.126 227.488 1.00 107.27 ? 242 PHE E CE2   1 
ATOM   5186  C  CZ    . PHE B 1 242 ? 381.697 360.866 227.492 1.00 107.98 ? 242 PHE E CZ    1 
ATOM   5187  N  N     . PRO B 1 243 ? 384.258 361.913 220.906 1.00 109.42 ? 243 PRO E N     1 
ATOM   5188  C  CA    . PRO B 1 243 ? 384.487 362.597 219.634 1.00 104.27 ? 243 PRO E CA    1 
ATOM   5189  C  C     . PRO B 1 243 ? 383.931 364.005 219.692 1.00 103.96 ? 243 PRO E C     1 
ATOM   5190  O  O     . PRO B 1 243 ? 383.000 364.310 220.441 1.00 103.94 ? 243 PRO E O     1 
ATOM   5191  C  CB    . PRO B 1 243 ? 383.737 361.733 218.617 1.00 106.94 ? 243 PRO E CB    1 
ATOM   5192  C  CG    . PRO B 1 243 ? 382.645 361.127 219.393 1.00 112.64 ? 243 PRO E CG    1 
ATOM   5193  C  CD    . PRO B 1 243 ? 383.200 360.892 220.767 1.00 114.92 ? 243 PRO E CD    1 
ATOM   5194  N  N     . GLY B 1 244 ? 384.525 364.870 218.883 1.00 94.61  ? 244 GLY E N     1 
ATOM   5195  C  CA    . GLY B 1 244 ? 384.175 366.273 218.908 1.00 95.74  ? 244 GLY E CA    1 
ATOM   5196  C  C     . GLY B 1 244 ? 384.440 366.894 217.563 1.00 100.28 ? 244 GLY E C     1 
ATOM   5197  O  O     . GLY B 1 244 ? 385.289 366.439 216.789 1.00 101.15 ? 244 GLY E O     1 
ATOM   5198  N  N     . GLN B 1 245 ? 383.682 367.949 217.295 1.00 103.46 ? 245 GLN E N     1 
ATOM   5199  C  CA    . GLN B 1 245 ? 383.667 368.552 215.977 1.00 99.84  ? 245 GLN E CA    1 
ATOM   5200  C  C     . GLN B 1 245 ? 384.860 369.481 215.782 1.00 100.03 ? 245 GLN E C     1 
ATOM   5201  O  O     . GLN B 1 245 ? 385.270 369.718 214.641 1.00 104.09 ? 245 GLN E O     1 
ATOM   5202  C  CB    . GLN B 1 245 ? 382.330 369.268 215.829 1.00 100.19 ? 245 GLN E CB    1 
ATOM   5203  C  CG    . GLN B 1 245 ? 382.052 369.923 214.490 1.00 102.07 ? 245 GLN E CG    1 
ATOM   5204  C  CD    . GLN B 1 245 ? 381.940 368.896 213.336 1.00 110.78 ? 245 GLN E CD    1 
ATOM   5205  O  OE1   . GLN B 1 245 ? 382.884 368.689 212.570 1.00 113.64 ? 245 GLN E OE1   1 
ATOM   5206  N  NE2   . GLN B 1 245 ? 380.805 368.246 213.238 1.00 108.05 ? 245 GLN E NE2   1 
ATOM   5207  N  N     . LEU B 1 246 ? 385.424 369.996 216.879 1.00 96.41  ? 246 LEU E N     1 
ATOM   5208  C  CA    . LEU B 1 246 ? 386.726 370.671 216.904 1.00 93.52  ? 246 LEU E CA    1 
ATOM   5209  C  C     . LEU B 1 246 ? 387.410 370.264 218.213 1.00 97.03  ? 246 LEU E C     1 
ATOM   5210  O  O     . LEU B 1 246 ? 387.162 370.855 219.266 1.00 101.25 ? 246 LEU E O     1 
ATOM   5211  C  CB    . LEU B 1 246 ? 386.579 372.182 216.796 1.00 94.65  ? 246 LEU E CB    1 
ATOM   5212  C  CG    . LEU B 1 246 ? 387.864 373.006 216.648 1.00 96.90  ? 246 LEU E CG    1 
ATOM   5213  C  CD1   . LEU B 1 246 ? 388.504 372.844 215.276 1.00 99.05  ? 246 LEU E CD1   1 
ATOM   5214  C  CD2   . LEU B 1 246 ? 387.577 374.475 216.929 1.00 98.66  ? 246 LEU E CD2   1 
ATOM   5215  N  N     . ASN B 1 247 ? 388.276 369.257 218.130 1.00 103.56 ? 247 ASN E N     1 
ATOM   5216  C  CA    . ASN B 1 247 ? 388.915 368.711 219.319 1.00 105.50 ? 247 ASN E CA    1 
ATOM   5217  C  C     . ASN B 1 247 ? 390.006 369.640 219.832 1.00 103.88 ? 247 ASN E C     1 
ATOM   5218  O  O     . ASN B 1 247 ? 390.589 370.427 219.082 1.00 105.85 ? 247 ASN E O     1 
ATOM   5219  C  CB    . ASN B 1 247 ? 389.518 367.336 219.031 1.00 106.24 ? 247 ASN E CB    1 
ATOM   5220  C  CG    . ASN B 1 247 ? 388.480 366.321 218.614 1.00 108.70 ? 247 ASN E CG    1 
ATOM   5221  O  OD1   . ASN B 1 247 ? 388.569 365.725 217.543 1.00 107.62 ? 247 ASN E OD1   1 
ATOM   5222  N  ND2   . ASN B 1 247 ? 387.493 366.103 219.475 1.00 110.60 ? 247 ASN E ND2   1 
ATOM   5223  N  N     . ALA B 1 248 ? 390.279 369.537 221.134 1.00 100.12 ? 248 ALA E N     1 
ATOM   5224  C  CA    . ALA B 1 248 ? 391.358 370.302 221.756 1.00 104.24 ? 248 ALA E CA    1 
ATOM   5225  C  C     . ALA B 1 248 ? 391.876 369.507 222.952 1.00 107.49 ? 248 ALA E C     1 
ATOM   5226  O  O     . ALA B 1 248 ? 391.294 369.564 224.039 1.00 103.78 ? 248 ALA E O     1 
ATOM   5227  C  CB    . ALA B 1 248 ? 390.887 371.689 222.168 1.00 105.64 ? 248 ALA E CB    1 
ATOM   5228  N  N     . ASP B 1 249 ? 392.965 368.774 222.741 1.00 122.14 ? 249 ASP E N     1 
ATOM   5229  C  CA    . ASP B 1 249 ? 393.614 368.057 223.830 1.00 115.46 ? 249 ASP E CA    1 
ATOM   5230  C  C     . ASP B 1 249 ? 394.342 369.034 224.753 1.00 115.31 ? 249 ASP E C     1 
ATOM   5231  O  O     . ASP B 1 249 ? 394.567 370.201 224.419 1.00 121.79 ? 249 ASP E O     1 
ATOM   5232  C  CB    . ASP B 1 249 ? 394.590 367.007 223.291 1.00 116.66 ? 249 ASP E CB    1 
ATOM   5233  C  CG    . ASP B 1 249 ? 395.655 367.596 222.391 1.00 120.84 ? 249 ASP E CG    1 
ATOM   5234  O  OD1   . ASP B 1 249 ? 395.347 367.894 221.219 1.00 119.10 ? 249 ASP E OD1   1 
ATOM   5235  O  OD2   . ASP B 1 249 ? 396.801 367.747 222.853 1.00 123.70 ? 249 ASP E OD2   1 
ATOM   5236  N  N     . LEU B 1 250 ? 394.701 368.544 225.942 1.00 106.86 ? 250 LEU E N     1 
ATOM   5237  C  CA    . LEU B 1 250 ? 395.230 369.441 226.965 1.00 107.62 ? 250 LEU E CA    1 
ATOM   5238  C  C     . LEU B 1 250 ? 396.643 369.921 226.647 1.00 105.77 ? 250 LEU E C     1 
ATOM   5239  O  O     . LEU B 1 250 ? 397.030 370.999 227.108 1.00 104.67 ? 250 LEU E O     1 
ATOM   5240  C  CB    . LEU B 1 250 ? 395.156 368.772 228.345 1.00 106.55 ? 250 LEU E CB    1 
ATOM   5241  C  CG    . LEU B 1 250 ? 395.774 367.401 228.643 1.00 109.75 ? 250 LEU E CG    1 
ATOM   5242  C  CD1   . LEU B 1 250 ? 397.252 367.504 228.993 1.00 109.81 ? 250 LEU E CD1   1 
ATOM   5243  C  CD2   . LEU B 1 250 ? 394.999 366.715 229.766 1.00 105.80 ? 250 LEU E CD2   1 
ATOM   5244  N  N     . ARG B 1 251 ? 397.408 369.180 225.841 1.00 110.27 ? 251 ARG E N     1 
ATOM   5245  C  CA    . ARG B 1 251 ? 398.636 369.755 225.301 1.00 108.81 ? 251 ARG E CA    1 
ATOM   5246  C  C     . ARG B 1 251 ? 398.325 370.944 224.400 1.00 104.13 ? 251 ARG E C     1 
ATOM   5247  O  O     . ARG B 1 251 ? 399.043 371.952 224.434 1.00 107.81 ? 251 ARG E O     1 
ATOM   5248  C  CB    . ARG B 1 251 ? 399.431 368.707 224.521 1.00 110.65 ? 251 ARG E CB    1 
ATOM   5249  C  CG    . ARG B 1 251 ? 400.886 369.083 224.253 1.00 107.06 ? 251 ARG E CG    1 
ATOM   5250  C  CD    . ARG B 1 251 ? 401.605 367.997 223.462 1.00 108.10 ? 251 ARG E CD    1 
ATOM   5251  N  NE    . ARG B 1 251 ? 401.982 366.843 224.275 1.00 112.33 ? 251 ARG E NE    1 
ATOM   5252  C  CZ    . ARG B 1 251 ? 403.081 366.746 225.016 1.00 112.62 ? 251 ARG E CZ    1 
ATOM   5253  N  NH1   . ARG B 1 251 ? 403.972 367.725 225.085 1.00 111.83 ? 251 ARG E NH1   1 
ATOM   5254  N  NH2   . ARG B 1 251 ? 403.296 365.632 225.709 1.00 112.70 ? 251 ARG E NH2   1 
ATOM   5255  N  N     . LYS B 1 252 ? 397.264 370.840 223.591 1.00 100.78 ? 252 LYS E N     1 
ATOM   5256  C  CA    . LYS B 1 252 ? 396.821 371.976 222.786 1.00 101.54 ? 252 LYS E CA    1 
ATOM   5257  C  C     . LYS B 1 252 ? 396.426 373.146 223.668 1.00 102.38 ? 252 LYS E C     1 
ATOM   5258  O  O     . LYS B 1 252 ? 396.749 374.301 223.361 1.00 105.42 ? 252 LYS E O     1 
ATOM   5259  C  CB    . LYS B 1 252 ? 395.633 371.585 221.904 1.00 105.70 ? 252 LYS E CB    1 
ATOM   5260  C  CG    . LYS B 1 252 ? 395.538 372.377 220.600 1.00 107.90 ? 252 LYS E CG    1 
ATOM   5261  C  CD    . LYS B 1 252 ? 394.611 371.732 219.588 1.00 108.66 ? 252 LYS E CD    1 
ATOM   5262  C  CE    . LYS B 1 252 ? 395.253 370.570 218.851 1.00 113.18 ? 252 LYS E CE    1 
ATOM   5263  N  NZ    . LYS B 1 252 ? 394.232 369.695 218.210 1.00 115.18 ? 252 LYS E NZ    1 
ATOM   5264  N  N     . LEU B 1 253 ? 395.717 372.863 224.765 1.00 107.09 ? 253 LEU E N     1 
ATOM   5265  C  CA    . LEU B 1 253 ? 395.338 373.920 225.695 1.00 108.98 ? 253 LEU E CA    1 
ATOM   5266  C  C     . LEU B 1 253 ? 396.566 374.606 226.268 1.00 108.81 ? 253 LEU E C     1 
ATOM   5267  O  O     . LEU B 1 253 ? 396.631 375.835 226.292 1.00 107.37 ? 253 LEU E O     1 
ATOM   5268  C  CB    . LEU B 1 253 ? 394.475 373.358 226.827 1.00 109.05 ? 253 LEU E CB    1 
ATOM   5269  C  CG    . LEU B 1 253 ? 393.081 372.818 226.491 1.00 111.05 ? 253 LEU E CG    1 
ATOM   5270  C  CD1   . LEU B 1 253 ? 392.441 372.208 227.730 1.00 111.82 ? 253 LEU E CD1   1 
ATOM   5271  C  CD2   . LEU B 1 253 ? 392.187 373.909 225.926 1.00 108.18 ? 253 LEU E CD2   1 
ATOM   5272  N  N     . ALA B 1 254 ? 397.567 373.827 226.686 1.00 117.82 ? 254 ALA E N     1 
ATOM   5273  C  CA    . ALA B 1 254 ? 398.780 374.405 227.262 1.00 117.69 ? 254 ALA E CA    1 
ATOM   5274  C  C     . ALA B 1 254 ? 399.534 375.258 226.248 1.00 114.96 ? 254 ALA E C     1 
ATOM   5275  O  O     . ALA B 1 254 ? 399.980 376.369 226.573 1.00 117.58 ? 254 ALA E O     1 
ATOM   5276  C  CB    . ALA B 1 254 ? 399.682 373.292 227.792 1.00 122.69 ? 254 ALA E CB    1 
ATOM   5277  N  N     . VAL B 1 255 ? 399.678 374.756 225.017 1.00 106.40 ? 255 VAL E N     1 
ATOM   5278  C  CA    . VAL B 1 255 ? 400.390 375.501 223.982 1.00 102.80 ? 255 VAL E CA    1 
ATOM   5279  C  C     . VAL B 1 255 ? 399.660 376.798 223.665 1.00 100.62 ? 255 VAL E C     1 
ATOM   5280  O  O     . VAL B 1 255 ? 400.286 377.844 223.461 1.00 105.70 ? 255 VAL E O     1 
ATOM   5281  C  CB    . VAL B 1 255 ? 400.575 374.631 222.723 1.00 101.34 ? 255 VAL E CB    1 
ATOM   5282  C  CG1   . VAL B 1 255 ? 401.059 375.467 221.533 1.00 98.43  ? 255 VAL E CG1   1 
ATOM   5283  C  CG2   . VAL B 1 255 ? 401.558 373.498 222.998 1.00 102.92 ? 255 VAL E CG2   1 
ATOM   5284  N  N     . ASN B 1 256 ? 398.330 376.756 223.612 1.00 95.10  ? 256 ASN E N     1 
ATOM   5285  C  CA    . ASN B 1 256 ? 397.578 377.980 223.367 1.00 94.92  ? 256 ASN E CA    1 
ATOM   5286  C  C     . ASN B 1 256 ? 397.677 378.939 224.547 1.00 99.74  ? 256 ASN E C     1 
ATOM   5287  O  O     . ASN B 1 256 ? 397.707 380.159 224.354 1.00 101.56 ? 256 ASN E O     1 
ATOM   5288  C  CB    . ASN B 1 256 ? 396.117 377.642 223.078 1.00 93.15  ? 256 ASN E CB    1 
ATOM   5289  C  CG    . ASN B 1 256 ? 395.896 377.200 221.647 1.00 97.27  ? 256 ASN E CG    1 
ATOM   5290  O  OD1   . ASN B 1 256 ? 395.739 378.022 220.747 1.00 97.12  ? 256 ASN E OD1   1 
ATOM   5291  N  ND2   . ASN B 1 256 ? 395.875 375.889 221.431 1.00 103.96 ? 256 ASN E ND2   1 
ATOM   5292  N  N     . MET B 1 257 ? 397.744 378.409 225.773 1.00 114.83 ? 257 MET E N     1 
ATOM   5293  C  CA    . MET B 1 257 ? 397.489 379.197 226.972 1.00 107.57 ? 257 MET E CA    1 
ATOM   5294  C  C     . MET B 1 257 ? 398.702 379.803 227.640 1.00 109.04 ? 257 MET E C     1 
ATOM   5295  O  O     . MET B 1 257 ? 398.538 380.796 228.355 1.00 107.10 ? 257 MET E O     1 
ATOM   5296  C  CB    . MET B 1 257 ? 396.811 378.339 228.040 1.00 110.41 ? 257 MET E CB    1 
ATOM   5297  C  CG    . MET B 1 257 ? 395.294 378.335 228.115 1.00 104.52 ? 257 MET E CG    1 
ATOM   5298  S  SD    . MET B 1 257 ? 394.579 380.000 228.172 1.00 126.72 ? 257 MET E SD    1 
ATOM   5299  C  CE    . MET B 1 257 ? 393.114 379.866 227.188 1.00 106.98 ? 257 MET E CE    1 
ATOM   5300  N  N     . VAL B 1 258 ? 399.878 379.202 227.507 1.00 108.11 ? 258 VAL E N     1 
ATOM   5301  C  CA    . VAL B 1 258 ? 401.054 379.663 228.241 1.00 102.04 ? 258 VAL E CA    1 
ATOM   5302  C  C     . VAL B 1 258 ? 401.901 380.486 227.274 1.00 106.06 ? 258 VAL E C     1 
ATOM   5303  O  O     . VAL B 1 258 ? 402.758 379.911 226.587 1.00 113.47 ? 258 VAL E O     1 
ATOM   5304  C  CB    . VAL B 1 258 ? 401.828 378.472 228.829 1.00 105.90 ? 258 VAL E CB    1 
ATOM   5305  C  CG1   . VAL B 1 258 ? 403.023 378.941 229.652 1.00 106.78 ? 258 VAL E CG1   1 
ATOM   5306  C  CG2   . VAL B 1 258 ? 400.893 377.599 229.670 1.00 108.81 ? 258 VAL E CG2   1 
ATOM   5307  N  N     . PRO B 1 259 ? 401.701 381.828 227.159 1.00 100.72 ? 259 PRO E N     1 
ATOM   5308  C  CA    . PRO B 1 259 ? 402.541 382.598 226.235 1.00 102.42 ? 259 PRO E CA    1 
ATOM   5309  C  C     . PRO B 1 259 ? 403.995 382.598 226.658 1.00 98.95  ? 259 PRO E C     1 
ATOM   5310  O  O     . PRO B 1 259 ? 404.896 382.452 225.826 1.00 95.19  ? 259 PRO E O     1 
ATOM   5311  C  CB    . PRO B 1 259 ? 401.942 384.009 226.296 1.00 95.98  ? 259 PRO E CB    1 
ATOM   5312  C  CG    . PRO B 1 259 ? 401.280 384.078 227.599 1.00 94.82  ? 259 PRO E CG    1 
ATOM   5313  C  CD    . PRO B 1 259 ? 400.731 382.711 227.833 1.00 99.45  ? 259 PRO E CD    1 
ATOM   5314  N  N     . PHE B 1 260 ? 404.217 382.743 227.961 1.00 88.96  ? 260 PHE E N     1 
ATOM   5315  C  CA    . PHE B 1 260 ? 405.533 382.735 228.567 1.00 87.12  ? 260 PHE E CA    1 
ATOM   5316  C  C     . PHE B 1 260 ? 405.558 381.692 229.676 1.00 93.63  ? 260 PHE E C     1 
ATOM   5317  O  O     . PHE B 1 260 ? 404.522 381.442 230.298 1.00 94.91  ? 260 PHE E O     1 
ATOM   5318  C  CB    . PHE B 1 260 ? 405.878 384.120 229.122 1.00 90.33  ? 260 PHE E CB    1 
ATOM   5319  C  CG    . PHE B 1 260 ? 405.689 385.218 228.118 1.00 94.05  ? 260 PHE E CG    1 
ATOM   5320  C  CD1   . PHE B 1 260 ? 406.690 385.535 227.219 1.00 95.60  ? 260 PHE E CD1   1 
ATOM   5321  C  CD2   . PHE B 1 260 ? 404.504 385.929 228.068 1.00 92.37  ? 260 PHE E CD2   1 
ATOM   5322  C  CE1   . PHE B 1 260 ? 406.510 386.537 226.287 1.00 96.06  ? 260 PHE E CE1   1 
ATOM   5323  C  CE2   . PHE B 1 260 ? 404.320 386.931 227.141 1.00 92.26  ? 260 PHE E CE2   1 
ATOM   5324  C  CZ    . PHE B 1 260 ? 405.322 387.235 226.246 1.00 95.06  ? 260 PHE E CZ    1 
ATOM   5325  N  N     . PRO B 1 261 ? 406.717 381.078 229.957 1.00 114.47 ? 261 PRO E N     1 
ATOM   5326  C  CA    . PRO B 1 261 ? 406.711 379.796 230.689 1.00 114.64 ? 261 PRO E CA    1 
ATOM   5327  C  C     . PRO B 1 261 ? 406.171 379.869 232.108 1.00 116.93 ? 261 PRO E C     1 
ATOM   5328  O  O     . PRO B 1 261 ? 405.803 378.823 232.657 1.00 118.44 ? 261 PRO E O     1 
ATOM   5329  C  CB    . PRO B 1 261 ? 408.191 379.384 230.689 1.00 116.83 ? 261 PRO E CB    1 
ATOM   5330  C  CG    . PRO B 1 261 ? 408.850 380.253 229.677 1.00 117.94 ? 261 PRO E CG    1 
ATOM   5331  C  CD    . PRO B 1 261 ? 408.099 381.532 229.716 1.00 117.06 ? 261 PRO E CD    1 
ATOM   5332  N  N     . ARG B 1 262 ? 406.101 381.059 232.708 1.00 117.55 ? 262 ARG E N     1 
ATOM   5333  C  CA    . ARG B 1 262 ? 405.677 381.217 234.093 1.00 119.58 ? 262 ARG E CA    1 
ATOM   5334  C  C     . ARG B 1 262 ? 404.222 381.644 234.238 1.00 114.01 ? 262 ARG E C     1 
ATOM   5335  O  O     . ARG B 1 262 ? 403.612 381.350 235.272 1.00 115.29 ? 262 ARG E O     1 
ATOM   5336  C  CB    . ARG B 1 262 ? 406.570 382.243 234.800 1.00 118.20 ? 262 ARG E CB    1 
ATOM   5337  C  CG    . ARG B 1 262 ? 408.062 382.066 234.515 1.00 117.78 ? 262 ARG E CG    1 
ATOM   5338  C  CD    . ARG B 1 262 ? 408.923 382.352 235.731 1.00 117.24 ? 262 ARG E CD    1 
ATOM   5339  N  NE    . ARG B 1 262 ? 408.570 383.605 236.390 1.00 117.96 ? 262 ARG E NE    1 
ATOM   5340  C  CZ    . ARG B 1 262 ? 408.958 383.965 237.608 1.00 121.33 ? 262 ARG E CZ    1 
ATOM   5341  N  NH1   . ARG B 1 262 ? 409.748 383.200 238.349 1.00 120.35 ? 262 ARG E NH1   1 
ATOM   5342  N  NH2   . ARG B 1 262 ? 408.544 385.129 238.099 1.00 124.84 ? 262 ARG E NH2   1 
ATOM   5343  N  N     . LEU B 1 263 ? 403.652 382.316 233.236 1.00 100.36 ? 263 LEU E N     1 
ATOM   5344  C  CA    . LEU B 1 263 ? 402.271 382.797 233.303 1.00 100.43 ? 263 LEU E CA    1 
ATOM   5345  C  C     . LEU B 1 263 ? 401.345 381.686 232.814 1.00 103.42 ? 263 LEU E C     1 
ATOM   5346  O  O     . LEU B 1 263 ? 400.898 381.660 231.664 1.00 108.99 ? 263 LEU E O     1 
ATOM   5347  C  CB    . LEU B 1 263 ? 402.110 384.076 232.489 1.00 98.57  ? 263 LEU E CB    1 
ATOM   5348  C  CG    . LEU B 1 263 ? 403.213 385.126 232.630 1.00 99.86  ? 263 LEU E CG    1 
ATOM   5349  C  CD1   . LEU B 1 263 ? 402.820 386.380 231.872 1.00 102.19 ? 263 LEU E CD1   1 
ATOM   5350  C  CD2   . LEU B 1 263 ? 403.504 385.444 234.087 1.00 100.02 ? 263 LEU E CD2   1 
ATOM   5351  N  N     . HIS B 1 264 ? 401.062 380.744 233.722 1.00 102.35 ? 264 HIS E N     1 
ATOM   5352  C  CA    . HIS B 1 264 ? 400.197 379.599 233.449 1.00 101.03 ? 264 HIS E CA    1 
ATOM   5353  C  C     . HIS B 1 264 ? 399.100 379.433 234.502 1.00 102.24 ? 264 HIS E C     1 
ATOM   5354  O  O     . HIS B 1 264 ? 398.538 378.342 234.633 1.00 111.37 ? 264 HIS E O     1 
ATOM   5355  C  CB    . HIS B 1 264 ? 401.037 378.324 233.334 1.00 102.17 ? 264 HIS E CB    1 
ATOM   5356  C  CG    . HIS B 1 264 ? 401.945 378.082 234.499 1.00 105.27 ? 264 HIS E CG    1 
ATOM   5357  N  ND1   . HIS B 1 264 ? 401.480 377.848 235.775 1.00 106.97 ? 264 HIS E ND1   1 
ATOM   5358  C  CD2   . HIS B 1 264 ? 403.295 378.031 234.577 1.00 104.86 ? 264 HIS E CD2   1 
ATOM   5359  C  CE1   . HIS B 1 264 ? 402.504 377.667 236.589 1.00 105.63 ? 264 HIS E CE1   1 
ATOM   5360  N  NE2   . HIS B 1 264 ? 403.617 377.773 235.887 1.00 105.26 ? 264 HIS E NE2   1 
ATOM   5361  N  N     . PHE B 1 265 ? 398.770 380.495 235.238 1.00 92.75  ? 265 PHE E N     1 
ATOM   5362  C  CA    . PHE B 1 265 ? 397.745 380.464 236.276 1.00 95.74  ? 265 PHE E CA    1 
ATOM   5363  C  C     . PHE B 1 265 ? 396.461 381.038 235.698 1.00 98.39  ? 265 PHE E C     1 
ATOM   5364  O  O     . PHE B 1 265 ? 396.415 382.223 235.350 1.00 102.72 ? 265 PHE E O     1 
ATOM   5365  C  CB    . PHE B 1 265 ? 398.186 381.263 237.498 1.00 96.26  ? 265 PHE E CB    1 
ATOM   5366  C  CG    . PHE B 1 265 ? 399.497 380.815 238.065 1.00 100.38 ? 265 PHE E CG    1 
ATOM   5367  C  CD1   . PHE B 1 265 ? 399.550 379.802 239.003 1.00 95.20  ? 265 PHE E CD1   1 
ATOM   5368  C  CD2   . PHE B 1 265 ? 400.679 381.400 237.651 1.00 104.54 ? 265 PHE E CD2   1 
ATOM   5369  C  CE1   . PHE B 1 265 ? 400.757 379.385 239.522 1.00 97.45  ? 265 PHE E CE1   1 
ATOM   5370  C  CE2   . PHE B 1 265 ? 401.888 380.987 238.164 1.00 103.09 ? 265 PHE E CE2   1 
ATOM   5371  C  CZ    . PHE B 1 265 ? 401.927 379.978 239.101 1.00 99.49  ? 265 PHE E CZ    1 
ATOM   5372  N  N     . PHE B 1 266 ? 395.425 380.207 235.612 1.00 97.34  ? 266 PHE E N     1 
ATOM   5373  C  CA    . PHE B 1 266 ? 394.210 380.529 234.880 1.00 96.70  ? 266 PHE E CA    1 
ATOM   5374  C  C     . PHE B 1 266 ? 393.015 380.648 235.813 1.00 94.75  ? 266 PHE E C     1 
ATOM   5375  O  O     . PHE B 1 266 ? 393.076 380.344 237.007 1.00 97.88  ? 266 PHE E O     1 
ATOM   5376  C  CB    . PHE B 1 266 ? 393.926 379.475 233.810 1.00 95.22  ? 266 PHE E CB    1 
ATOM   5377  C  CG    . PHE B 1 266 ? 395.129 379.091 233.020 1.00 93.82  ? 266 PHE E CG    1 
ATOM   5378  C  CD1   . PHE B 1 266 ? 395.943 380.058 232.466 1.00 92.91  ? 266 PHE E CD1   1 
ATOM   5379  C  CD2   . PHE B 1 266 ? 395.454 377.763 232.834 1.00 96.99  ? 266 PHE E CD2   1 
ATOM   5380  C  CE1   . PHE B 1 266 ? 397.047 379.706 231.747 1.00 97.86  ? 266 PHE E CE1   1 
ATOM   5381  C  CE2   . PHE B 1 266 ? 396.564 377.415 232.114 1.00 98.89  ? 266 PHE E CE2   1 
ATOM   5382  C  CZ    . PHE B 1 266 ? 397.365 378.380 231.587 1.00 102.42 ? 266 PHE E CZ    1 
ATOM   5383  N  N     . MET B 1 267 ? 391.915 381.088 235.212 1.00 99.43  ? 267 MET E N     1 
ATOM   5384  C  CA    . MET B 1 267 ? 390.664 381.410 235.893 1.00 101.23 ? 267 MET E CA    1 
ATOM   5385  C  C     . MET B 1 267 ? 389.589 380.541 235.250 1.00 103.22 ? 267 MET E C     1 
ATOM   5386  O  O     . MET B 1 267 ? 389.259 380.760 234.069 1.00 114.33 ? 267 MET E O     1 
ATOM   5387  C  CB    . MET B 1 267 ? 390.346 382.890 235.711 1.00 106.09 ? 267 MET E CB    1 
ATOM   5388  C  CG    . MET B 1 267 ? 390.919 383.764 236.809 1.00 112.37 ? 267 MET E CG    1 
ATOM   5389  S  SD    . MET B 1 267 ? 390.963 385.543 236.475 1.00 125.91 ? 267 MET E SD    1 
ATOM   5390  C  CE    . MET B 1 267 ? 389.747 385.772 235.179 1.00 106.80 ? 267 MET E CE    1 
ATOM   5391  N  N     . PRO B 1 268 ? 389.056 379.520 235.929 1.00 98.73  ? 268 PRO E N     1 
ATOM   5392  C  CA    . PRO B 1 268 ? 388.039 378.672 235.302 1.00 99.99  ? 268 PRO E CA    1 
ATOM   5393  C  C     . PRO B 1 268 ? 386.634 379.241 235.468 1.00 102.26 ? 268 PRO E C     1 
ATOM   5394  O  O     . PRO B 1 268 ? 386.393 380.192 236.212 1.00 102.55 ? 268 PRO E O     1 
ATOM   5395  C  CB    . PRO B 1 268 ? 388.182 377.338 236.035 1.00 103.99 ? 268 PRO E CB    1 
ATOM   5396  C  CG    . PRO B 1 268 ? 388.702 377.687 237.349 1.00 106.94 ? 268 PRO E CG    1 
ATOM   5397  C  CD    . PRO B 1 268 ? 389.428 378.990 237.255 1.00 109.03 ? 268 PRO E CD    1 
ATOM   5398  N  N     . GLY B 1 269 ? 385.700 378.620 234.751 1.00 103.25 ? 269 GLY E N     1 
ATOM   5399  C  CA    . GLY B 1 269 ? 384.295 378.981 234.818 1.00 99.01  ? 269 GLY E CA    1 
ATOM   5400  C  C     . GLY B 1 269 ? 383.468 377.973 234.051 1.00 98.12  ? 269 GLY E C     1 
ATOM   5401  O  O     . GLY B 1 269 ? 383.997 377.137 233.317 1.00 105.54 ? 269 GLY E O     1 
ATOM   5402  N  N     . PHE B 1 270 ? 382.148 378.083 234.199 1.00 91.15  ? 270 PHE E N     1 
ATOM   5403  C  CA    . PHE B 1 270 ? 381.238 377.101 233.622 1.00 94.78  ? 270 PHE E CA    1 
ATOM   5404  C  C     . PHE B 1 270 ? 379.877 377.744 233.401 1.00 100.90 ? 270 PHE E C     1 
ATOM   5405  O  O     . PHE B 1 270 ? 379.497 378.674 234.116 1.00 106.53 ? 270 PHE E O     1 
ATOM   5406  C  CB    . PHE B 1 270 ? 381.112 375.877 234.538 1.00 99.13  ? 270 PHE E CB    1 
ATOM   5407  C  CG    . PHE B 1 270 ? 380.346 374.734 233.935 1.00 100.38 ? 270 PHE E CG    1 
ATOM   5408  C  CD1   . PHE B 1 270 ? 380.976 373.812 233.119 1.00 104.56 ? 270 PHE E CD1   1 
ATOM   5409  C  CD2   . PHE B 1 270 ? 378.997 374.578 234.192 1.00 99.89  ? 270 PHE E CD2   1 
ATOM   5410  C  CE1   . PHE B 1 270 ? 380.272 372.760 232.568 1.00 103.05 ? 270 PHE E CE1   1 
ATOM   5411  C  CE2   . PHE B 1 270 ? 378.288 373.529 233.645 1.00 100.20 ? 270 PHE E CE2   1 
ATOM   5412  C  CZ    . PHE B 1 270 ? 378.926 372.619 232.832 1.00 101.56 ? 270 PHE E CZ    1 
ATOM   5413  N  N     . ALA B 1 271 ? 379.153 377.245 232.398 1.00 109.42 ? 271 ALA E N     1 
ATOM   5414  C  CA    . ALA B 1 271 ? 377.769 377.652 232.188 1.00 112.48 ? 271 ALA E CA    1 
ATOM   5415  C  C     . ALA B 1 271 ? 377.039 376.533 231.457 1.00 111.43 ? 271 ALA E C     1 
ATOM   5416  O  O     . ALA B 1 271 ? 377.683 375.741 230.762 1.00 113.75 ? 271 ALA E O     1 
ATOM   5417  C  CB    . ALA B 1 271 ? 377.689 378.960 231.387 1.00 116.21 ? 271 ALA E CB    1 
ATOM   5418  N  N     . PRO B 1 272 ? 375.696 376.429 231.591 1.00 107.98 ? 272 PRO E N     1 
ATOM   5419  C  CA    . PRO B 1 272 ? 374.761 377.213 232.409 1.00 111.69 ? 272 PRO E CA    1 
ATOM   5420  C  C     . PRO B 1 272 ? 374.721 376.709 233.848 1.00 111.39 ? 272 PRO E C     1 
ATOM   5421  O  O     . PRO B 1 272 ? 374.969 375.529 234.077 1.00 110.57 ? 272 PRO E O     1 
ATOM   5422  C  CB    . PRO B 1 272 ? 373.433 377.005 231.680 1.00 111.51 ? 272 PRO E CB    1 
ATOM   5423  C  CG    . PRO B 1 272 ? 373.522 375.595 231.182 1.00 104.98 ? 272 PRO E CG    1 
ATOM   5424  C  CD    . PRO B 1 272 ? 374.992 375.330 230.906 1.00 107.88 ? 272 PRO E CD    1 
ATOM   5425  N  N     . LEU B 1 273 ? 374.397 377.572 234.811 1.00 120.53 ? 273 LEU E N     1 
ATOM   5426  C  CA    . LEU B 1 273 ? 374.337 377.231 236.233 1.00 122.39 ? 273 LEU E CA    1 
ATOM   5427  C  C     . LEU B 1 273 ? 373.052 377.782 236.844 1.00 125.00 ? 273 LEU E C     1 
ATOM   5428  O  O     . LEU B 1 273 ? 373.014 378.185 238.011 1.00 133.20 ? 273 LEU E O     1 
ATOM   5429  C  CB    . LEU B 1 273 ? 375.571 377.771 236.968 1.00 125.82 ? 273 LEU E CB    1 
ATOM   5430  C  CG    . LEU B 1 273 ? 376.957 377.141 236.771 1.00 128.08 ? 273 LEU E CG    1 
ATOM   5431  C  CD1   . LEU B 1 273 ? 377.873 377.615 237.879 1.00 130.21 ? 273 LEU E CD1   1 
ATOM   5432  C  CD2   . LEU B 1 273 ? 376.930 375.623 236.777 1.00 126.25 ? 273 LEU E CD2   1 
ATOM   5433  N  N     . THR B 1 274 ? 371.969 377.773 236.075 1.00 143.92 ? 274 THR E N     1 
ATOM   5434  C  CA    . THR B 1 274 ? 370.723 378.353 236.542 1.00 150.71 ? 274 THR E CA    1 
ATOM   5435  C  C     . THR B 1 274 ? 370.086 377.482 237.620 1.00 152.51 ? 274 THR E C     1 
ATOM   5436  O  O     . THR B 1 274 ? 370.316 376.273 237.698 1.00 150.99 ? 274 THR E O     1 
ATOM   5437  C  CB    . THR B 1 274 ? 369.746 378.530 235.382 1.00 152.29 ? 274 THR E CB    1 
ATOM   5438  O  OG1   . THR B 1 274 ? 369.879 377.434 234.469 1.00 149.17 ? 274 THR E OG1   1 
ATOM   5439  C  CG2   . THR B 1 274 ? 370.016 379.832 234.651 1.00 150.30 ? 274 THR E CG2   1 
ATOM   5440  N  N     . SER B 1 275 ? 369.273 378.119 238.457 1.00 167.25 ? 275 SER E N     1 
ATOM   5441  C  CA    . SER B 1 275 ? 368.538 377.418 239.495 1.00 166.28 ? 275 SER E CA    1 
ATOM   5442  C  C     . SER B 1 275 ? 367.344 376.693 238.884 1.00 169.06 ? 275 SER E C     1 
ATOM   5443  O  O     . SER B 1 275 ? 367.069 376.798 237.687 1.00 172.63 ? 275 SER E O     1 
ATOM   5444  C  CB    . SER B 1 275 ? 368.087 378.396 240.574 1.00 168.12 ? 275 SER E CB    1 
ATOM   5445  O  OG    . SER B 1 275 ? 367.030 379.217 240.112 1.00 169.34 ? 275 SER E OG    1 
ATOM   5446  N  N     . ARG B 1 276 ? 366.617 375.954 239.730 1.00 170.26 ? 276 ARG E N     1 
ATOM   5447  C  CA    . ARG B 1 276 ? 365.514 375.127 239.248 1.00 171.43 ? 276 ARG E CA    1 
ATOM   5448  C  C     . ARG B 1 276 ? 364.400 375.971 238.639 1.00 170.91 ? 276 ARG E C     1 
ATOM   5449  O  O     . ARG B 1 276 ? 363.807 375.591 237.623 1.00 172.43 ? 276 ARG E O     1 
ATOM   5450  C  CB    . ARG B 1 276 ? 364.968 374.274 240.393 1.00 168.83 ? 276 ARG E CB    1 
ATOM   5451  N  N     . GLY B 1 277 ? 364.093 377.115 239.250 1.00 171.17 ? 277 GLY E N     1 
ATOM   5452  C  CA    . GLY B 1 277 ? 363.043 377.965 238.715 1.00 172.89 ? 277 GLY E CA    1 
ATOM   5453  C  C     . GLY B 1 277 ? 363.413 378.614 237.394 1.00 176.96 ? 277 GLY E C     1 
ATOM   5454  O  O     . GLY B 1 277 ? 362.562 378.785 236.517 1.00 180.04 ? 277 GLY E O     1 
ATOM   5455  N  N     . SER B 1 278 ? 364.685 378.982 237.229 1.00 191.65 ? 278 SER E N     1 
ATOM   5456  C  CA    . SER B 1 278 ? 365.077 379.882 236.151 1.00 193.69 ? 278 SER E CA    1 
ATOM   5457  C  C     . SER B 1 278 ? 365.176 379.211 234.784 1.00 194.31 ? 278 SER E C     1 
ATOM   5458  O  O     . SER B 1 278 ? 365.089 379.914 233.768 1.00 195.37 ? 278 SER E O     1 
ATOM   5459  C  CB    . SER B 1 278 ? 366.416 380.540 236.488 1.00 192.04 ? 278 SER E CB    1 
ATOM   5460  O  OG    . SER B 1 278 ? 366.302 381.365 237.634 1.00 192.51 ? 278 SER E OG    1 
ATOM   5461  N  N     . GLN B 1 279 ? 365.371 377.888 234.719 1.00 187.94 ? 279 GLN E N     1 
ATOM   5462  C  CA    . GLN B 1 279 ? 365.507 377.249 233.411 1.00 185.72 ? 279 GLN E CA    1 
ATOM   5463  C  C     . GLN B 1 279 ? 364.211 377.313 232.615 1.00 185.50 ? 279 GLN E C     1 
ATOM   5464  O  O     . GLN B 1 279 ? 364.248 377.327 231.380 1.00 186.48 ? 279 GLN E O     1 
ATOM   5465  C  CB    . GLN B 1 279 ? 365.944 375.784 233.529 1.00 184.51 ? 279 GLN E CB    1 
ATOM   5466  C  CG    . GLN B 1 279 ? 367.148 375.497 234.449 1.00 187.28 ? 279 GLN E CG    1 
ATOM   5467  C  CD    . GLN B 1 279 ? 366.830 374.641 235.675 1.00 187.21 ? 279 GLN E CD    1 
ATOM   5468  O  OE1   . GLN B 1 279 ? 365.673 374.423 236.035 1.00 185.52 ? 279 GLN E OE1   1 
ATOM   5469  N  NE2   . GLN B 1 279 ? 367.880 374.155 236.327 1.00 187.05 ? 279 GLN E NE2   1 
ATOM   5470  N  N     . GLN B 1 280 ? 363.064 377.340 233.295 1.00 184.45 ? 280 GLN E N     1 
ATOM   5471  C  CA    . GLN B 1 280 ? 361.794 377.442 232.584 1.00 184.58 ? 280 GLN E CA    1 
ATOM   5472  C  C     . GLN B 1 280 ? 361.678 378.780 231.865 1.00 185.63 ? 280 GLN E C     1 
ATOM   5473  O  O     . GLN B 1 280 ? 361.221 378.836 230.717 1.00 183.90 ? 280 GLN E O     1 
ATOM   5474  C  CB    . GLN B 1 280 ? 360.621 377.252 233.550 1.00 183.95 ? 280 GLN E CB    1 
ATOM   5475  C  CG    . GLN B 1 280 ? 360.720 376.039 234.480 1.00 182.78 ? 280 GLN E CG    1 
ATOM   5476  C  CD    . GLN B 1 280 ? 361.060 374.751 233.754 1.00 182.83 ? 280 GLN E CD    1 
ATOM   5477  O  OE1   . GLN B 1 280 ? 361.965 374.020 234.157 1.00 181.85 ? 280 GLN E OE1   1 
ATOM   5478  N  NE2   . GLN B 1 280 ? 360.335 374.465 232.679 1.00 183.44 ? 280 GLN E NE2   1 
ATOM   5479  N  N     . TYR B 1 281 ? 362.091 379.866 232.521 1.00 202.47 ? 281 TYR E N     1 
ATOM   5480  C  CA    . TYR B 1 281 ? 362.020 381.181 231.895 1.00 201.36 ? 281 TYR E CA    1 
ATOM   5481  C  C     . TYR B 1 281 ? 363.102 381.366 230.838 1.00 199.79 ? 281 TYR E C     1 
ATOM   5482  O  O     . TYR B 1 281 ? 362.823 381.877 229.748 1.00 200.34 ? 281 TYR E O     1 
ATOM   5483  C  CB    . TYR B 1 281 ? 362.133 382.277 232.955 1.00 200.19 ? 281 TYR E CB    1 
ATOM   5484  C  CG    . TYR B 1 281 ? 361.112 382.163 234.062 1.00 201.26 ? 281 TYR E CG    1 
ATOM   5485  C  CD1   . TYR B 1 281 ? 359.837 382.688 233.911 1.00 201.74 ? 281 TYR E CD1   1 
ATOM   5486  C  CD2   . TYR B 1 281 ? 361.425 381.537 235.260 1.00 201.06 ? 281 TYR E CD2   1 
ATOM   5487  C  CE1   . TYR B 1 281 ? 358.900 382.589 234.920 1.00 201.19 ? 281 TYR E CE1   1 
ATOM   5488  C  CE2   . TYR B 1 281 ? 360.495 381.432 236.274 1.00 201.18 ? 281 TYR E CE2   1 
ATOM   5489  C  CZ    . TYR B 1 281 ? 359.234 381.960 236.099 1.00 200.73 ? 281 TYR E CZ    1 
ATOM   5490  O  OH    . TYR B 1 281 ? 358.304 381.859 237.108 1.00 200.46 ? 281 TYR E OH    1 
ATOM   5491  N  N     . ARG B 1 282 ? 364.333 380.955 231.132 1.00 177.21 ? 282 ARG E N     1 
ATOM   5492  C  CA    . ARG B 1 282 ? 365.439 381.212 230.221 1.00 175.61 ? 282 ARG E CA    1 
ATOM   5493  C  C     . ARG B 1 282 ? 365.451 380.212 229.071 1.00 174.86 ? 282 ARG E C     1 
ATOM   5494  O  O     . ARG B 1 282 ? 365.047 379.055 229.218 1.00 175.78 ? 282 ARG E O     1 
ATOM   5495  C  CB    . ARG B 1 282 ? 366.778 381.162 230.958 1.00 175.07 ? 282 ARG E CB    1 
ATOM   5496  C  CG    . ARG B 1 282 ? 367.245 382.521 231.450 1.00 175.16 ? 282 ARG E CG    1 
ATOM   5497  C  CD    . ARG B 1 282 ? 368.604 382.436 232.113 1.00 174.23 ? 282 ARG E CD    1 
ATOM   5498  N  NE    . ARG B 1 282 ? 369.002 383.706 232.711 1.00 175.73 ? 282 ARG E NE    1 
ATOM   5499  C  CZ    . ARG B 1 282 ? 370.080 383.895 233.465 1.00 177.58 ? 282 ARG E CZ    1 
ATOM   5500  N  NH1   . ARG B 1 282 ? 370.920 382.909 233.748 1.00 175.85 ? 282 ARG E NH1   1 
ATOM   5501  N  NH2   . ARG B 1 282 ? 370.324 385.109 233.949 1.00 178.03 ? 282 ARG E NH2   1 
ATOM   5502  N  N     . ALA B 1 283 ? 365.926 380.682 227.916 1.00 157.14 ? 283 ALA E N     1 
ATOM   5503  C  CA    . ALA B 1 283 ? 366.089 379.877 226.708 1.00 155.73 ? 283 ALA E CA    1 
ATOM   5504  C  C     . ALA B 1 283 ? 367.581 379.676 226.484 1.00 155.50 ? 283 ALA E C     1 
ATOM   5505  O  O     . ALA B 1 283 ? 368.301 380.629 226.167 1.00 157.05 ? 283 ALA E O     1 
ATOM   5506  C  CB    . ALA B 1 283 ? 365.436 380.552 225.502 1.00 155.72 ? 283 ALA E CB    1 
ATOM   5507  N  N     . LEU B 1 284 ? 368.041 378.441 226.654 1.00 141.50 ? 284 LEU E N     1 
ATOM   5508  C  CA    . LEU B 1 284 ? 369.462 378.142 226.555 1.00 140.64 ? 284 LEU E CA    1 
ATOM   5509  C  C     . LEU B 1 284 ? 369.932 378.285 225.113 1.00 141.32 ? 284 LEU E C     1 
ATOM   5510  O  O     . LEU B 1 284 ? 369.503 377.533 224.233 1.00 141.66 ? 284 LEU E O     1 
ATOM   5511  C  CB    . LEU B 1 284 ? 369.716 376.729 227.084 1.00 140.50 ? 284 LEU E CB    1 
ATOM   5512  C  CG    . LEU B 1 284 ? 371.086 376.062 226.934 1.00 142.97 ? 284 LEU E CG    1 
ATOM   5513  C  CD1   . LEU B 1 284 ? 372.246 377.035 227.137 1.00 144.73 ? 284 LEU E CD1   1 
ATOM   5514  C  CD2   . LEU B 1 284 ? 371.209 374.898 227.902 1.00 143.23 ? 284 LEU E CD2   1 
ATOM   5515  N  N     . THR B 1 285 ? 370.816 379.257 224.880 1.00 145.39 ? 285 THR E N     1 
ATOM   5516  C  CA    . THR B 1 285 ? 371.384 379.521 223.566 1.00 142.35 ? 285 THR E CA    1 
ATOM   5517  C  C     . THR B 1 285 ? 372.862 379.837 223.725 1.00 139.79 ? 285 THR E C     1 
ATOM   5518  O  O     . THR B 1 285 ? 373.332 380.160 224.821 1.00 142.05 ? 285 THR E O     1 
ATOM   5519  C  CB    . THR B 1 285 ? 370.696 380.690 222.848 1.00 143.38 ? 285 THR E CB    1 
ATOM   5520  O  OG1   . THR B 1 285 ? 370.975 381.911 223.544 1.00 145.66 ? 285 THR E OG1   1 
ATOM   5521  C  CG2   . THR B 1 285 ? 369.193 380.479 222.764 1.00 141.75 ? 285 THR E CG2   1 
ATOM   5522  N  N     . VAL B 1 286 ? 373.589 379.728 222.619 1.00 119.24 ? 286 VAL E N     1 
ATOM   5523  C  CA    . VAL B 1 286 ? 375.023 380.007 222.599 1.00 119.71 ? 286 VAL E CA    1 
ATOM   5524  C  C     . VAL B 1 286 ? 375.301 381.464 222.966 1.00 125.49 ? 286 VAL E C     1 
ATOM   5525  O  O     . VAL B 1 286 ? 376.281 381.710 223.684 1.00 132.15 ? 286 VAL E O     1 
ATOM   5526  C  CB    . VAL B 1 286 ? 375.659 379.632 221.247 1.00 124.58 ? 286 VAL E CB    1 
ATOM   5527  C  CG1   . VAL B 1 286 ? 377.172 379.790 221.318 1.00 127.06 ? 286 VAL E CG1   1 
ATOM   5528  C  CG2   . VAL B 1 286 ? 375.301 378.187 220.862 1.00 126.70 ? 286 VAL E CG2   1 
ATOM   5529  N  N     . PRO B 1 287 ? 374.542 382.462 222.474 1.00 133.33 ? 287 PRO E N     1 
ATOM   5530  C  CA    . PRO B 1 287 ? 374.734 383.826 223.006 1.00 137.78 ? 287 PRO E CA    1 
ATOM   5531  C  C     . PRO B 1 287 ? 374.579 383.931 224.512 1.00 137.46 ? 287 PRO E C     1 
ATOM   5532  O  O     . PRO B 1 287 ? 375.378 384.614 225.171 1.00 138.50 ? 287 PRO E O     1 
ATOM   5533  C  CB    . PRO B 1 287 ? 373.654 384.637 222.281 1.00 137.81 ? 287 PRO E CB    1 
ATOM   5534  C  CG    . PRO B 1 287 ? 373.414 383.930 221.028 1.00 136.93 ? 287 PRO E CG    1 
ATOM   5535  C  CD    . PRO B 1 287 ? 373.757 382.488 221.223 1.00 134.41 ? 287 PRO E CD    1 
ATOM   5536  N  N     . GLU B 1 288 ? 373.583 383.245 225.077 1.00 128.68 ? 288 GLU E N     1 
ATOM   5537  C  CA    . GLU B 1 288 ? 373.382 383.281 226.520 1.00 126.91 ? 288 GLU E CA    1 
ATOM   5538  C  C     . GLU B 1 288 ? 374.570 382.662 227.243 1.00 131.04 ? 288 GLU E C     1 
ATOM   5539  O  O     . GLU B 1 288 ? 375.059 383.216 228.234 1.00 134.25 ? 288 GLU E O     1 
ATOM   5540  C  CB    . GLU B 1 288 ? 372.061 382.576 226.862 1.00 124.20 ? 288 GLU E CB    1 
ATOM   5541  C  CG    . GLU B 1 288 ? 371.757 382.285 228.352 1.00 130.40 ? 288 GLU E CG    1 
ATOM   5542  C  CD    . GLU B 1 288 ? 372.390 381.009 228.910 1.00 136.52 ? 288 GLU E CD    1 
ATOM   5543  O  OE1   . GLU B 1 288 ? 372.880 380.175 228.118 1.00 137.26 ? 288 GLU E OE1   1 
ATOM   5544  O  OE2   . GLU B 1 288 ? 372.396 380.846 230.148 1.00 135.08 ? 288 GLU E OE2   1 
ATOM   5545  N  N     . LEU B 1 289 ? 375.058 381.524 226.745 1.00 117.96 ? 289 LEU E N     1 
ATOM   5546  C  CA    . LEU B 1 289 ? 376.197 380.868 227.377 1.00 117.46 ? 289 LEU E CA    1 
ATOM   5547  C  C     . LEU B 1 289 ? 377.450 381.724 227.294 1.00 114.97 ? 289 LEU E C     1 
ATOM   5548  O  O     . LEU B 1 289 ? 378.218 381.808 228.261 1.00 119.27 ? 289 LEU E O     1 
ATOM   5549  C  CB    . LEU B 1 289 ? 376.447 379.513 226.722 1.00 116.58 ? 289 LEU E CB    1 
ATOM   5550  C  CG    . LEU B 1 289 ? 375.458 378.382 226.988 1.00 117.81 ? 289 LEU E CG    1 
ATOM   5551  C  CD1   . LEU B 1 289 ? 375.907 377.171 226.214 1.00 117.89 ? 289 LEU E CD1   1 
ATOM   5552  C  CD2   . LEU B 1 289 ? 375.352 378.049 228.465 1.00 118.60 ? 289 LEU E CD2   1 
ATOM   5553  N  N     . THR B 1 290 ? 377.684 382.355 226.141 1.00 110.77 ? 290 THR E N     1 
ATOM   5554  C  CA    . THR B 1 290 ? 378.873 383.184 225.989 1.00 112.33 ? 290 THR E CA    1 
ATOM   5555  C  C     . THR B 1 290 ? 378.823 384.382 226.926 1.00 119.16 ? 290 THR E C     1 
ATOM   5556  O  O     . THR B 1 290 ? 379.808 384.681 227.614 1.00 127.52 ? 290 THR E O     1 
ATOM   5557  C  CB    . THR B 1 290 ? 379.009 383.648 224.542 1.00 117.36 ? 290 THR E CB    1 
ATOM   5558  O  OG1   . THR B 1 290 ? 377.745 384.134 224.080 1.00 127.62 ? 290 THR E OG1   1 
ATOM   5559  C  CG2   . THR B 1 290 ? 379.474 382.500 223.644 1.00 114.95 ? 290 THR E CG2   1 
ATOM   5560  N  N     . GLN B 1 291 ? 377.677 385.066 226.988 1.00 116.74 ? 291 GLN E N     1 
ATOM   5561  C  CA    . GLN B 1 291 ? 377.565 386.211 227.883 1.00 118.54 ? 291 GLN E CA    1 
ATOM   5562  C  C     . GLN B 1 291 ? 377.672 385.781 229.340 1.00 120.26 ? 291 GLN E C     1 
ATOM   5563  O  O     . GLN B 1 291 ? 378.221 386.516 230.169 1.00 126.93 ? 291 GLN E O     1 
ATOM   5564  C  CB    . GLN B 1 291 ? 376.251 386.954 227.627 1.00 121.15 ? 291 GLN E CB    1 
ATOM   5565  C  CG    . GLN B 1 291 ? 376.142 387.629 226.251 1.00 125.64 ? 291 GLN E CG    1 
ATOM   5566  C  CD    . GLN B 1 291 ? 377.195 388.704 226.014 1.00 128.48 ? 291 GLN E CD    1 
ATOM   5567  O  OE1   . GLN B 1 291 ? 377.248 389.703 226.730 1.00 129.99 ? 291 GLN E OE1   1 
ATOM   5568  N  NE2   . GLN B 1 291 ? 378.040 388.499 225.008 1.00 124.84 ? 291 GLN E NE2   1 
ATOM   5569  N  N     . GLN B 1 292 ? 377.195 384.578 229.669 1.00 116.20 ? 292 GLN E N     1 
ATOM   5570  C  CA    . GLN B 1 292 ? 377.296 384.112 231.047 1.00 121.00 ? 292 GLN E CA    1 
ATOM   5571  C  C     . GLN B 1 292 ? 378.738 383.796 231.431 1.00 122.72 ? 292 GLN E C     1 
ATOM   5572  O  O     . GLN B 1 292 ? 379.187 384.180 232.517 1.00 127.71 ? 292 GLN E O     1 
ATOM   5573  C  CB    . GLN B 1 292 ? 376.407 382.889 231.254 1.00 117.96 ? 292 GLN E CB    1 
ATOM   5574  C  CG    . GLN B 1 292 ? 376.467 382.331 232.664 1.00 123.81 ? 292 GLN E CG    1 
ATOM   5575  C  CD    . GLN B 1 292 ? 375.147 381.749 233.116 1.00 125.55 ? 292 GLN E CD    1 
ATOM   5576  O  OE1   . GLN B 1 292 ? 374.991 380.534 233.208 1.00 125.04 ? 292 GLN E OE1   1 
ATOM   5577  N  NE2   . GLN B 1 292 ? 374.185 382.617 233.403 1.00 125.20 ? 292 GLN E NE2   1 
ATOM   5578  N  N     . VAL B 1 293 ? 379.479 383.089 230.572 1.00 115.83 ? 293 VAL E N     1 
ATOM   5579  C  CA    . VAL B 1 293 ? 380.853 382.736 230.932 1.00 110.71 ? 293 VAL E CA    1 
ATOM   5580  C  C     . VAL B 1 293 ? 381.736 383.979 230.952 1.00 113.25 ? 293 VAL E C     1 
ATOM   5581  O  O     . VAL B 1 293 ? 382.590 384.131 231.832 1.00 118.85 ? 293 VAL E O     1 
ATOM   5582  C  CB    . VAL B 1 293 ? 381.430 381.644 230.004 1.00 115.56 ? 293 VAL E CB    1 
ATOM   5583  C  CG1   . VAL B 1 293 ? 380.634 380.359 230.134 1.00 116.89 ? 293 VAL E CG1   1 
ATOM   5584  C  CG2   . VAL B 1 293 ? 381.526 382.093 228.549 1.00 118.47 ? 293 VAL E CG2   1 
ATOM   5585  N  N     . PHE B 1 294 ? 381.543 384.890 229.996 1.00 108.92 ? 294 PHE E N     1 
ATOM   5586  C  CA    . PHE B 1 294 ? 382.268 386.155 229.987 1.00 110.90 ? 294 PHE E CA    1 
ATOM   5587  C  C     . PHE B 1 294 ? 381.770 387.152 231.024 1.00 113.83 ? 294 PHE E C     1 
ATOM   5588  O  O     . PHE B 1 294 ? 382.408 388.194 231.202 1.00 113.02 ? 294 PHE E O     1 
ATOM   5589  C  CB    . PHE B 1 294 ? 382.195 386.765 228.582 1.00 112.51 ? 294 PHE E CB    1 
ATOM   5590  C  CG    . PHE B 1 294 ? 383.117 386.114 227.577 1.00 110.66 ? 294 PHE E CG    1 
ATOM   5591  C  CD1   . PHE B 1 294 ? 384.493 386.192 227.728 1.00 112.15 ? 294 PHE E CD1   1 
ATOM   5592  C  CD2   . PHE B 1 294 ? 382.615 385.353 226.533 1.00 112.66 ? 294 PHE E CD2   1 
ATOM   5593  C  CE1   . PHE B 1 294 ? 385.342 385.609 226.817 1.00 116.34 ? 294 PHE E CE1   1 
ATOM   5594  C  CE2   . PHE B 1 294 ? 383.466 384.745 225.628 1.00 112.52 ? 294 PHE E CE2   1 
ATOM   5595  C  CZ    . PHE B 1 294 ? 384.831 384.868 225.776 1.00 115.85 ? 294 PHE E CZ    1 
ATOM   5596  N  N     . ASP B 1 295 ? 380.664 386.875 231.708 1.00 127.24 ? 295 ASP E N     1 
ATOM   5597  C  CA    . ASP B 1 295 ? 380.280 387.703 232.840 1.00 127.13 ? 295 ASP E CA    1 
ATOM   5598  C  C     . ASP B 1 295 ? 381.293 387.550 233.968 1.00 124.40 ? 295 ASP E C     1 
ATOM   5599  O  O     . ASP B 1 295 ? 381.755 386.445 234.264 1.00 124.50 ? 295 ASP E O     1 
ATOM   5600  C  CB    . ASP B 1 295 ? 378.886 387.316 233.331 1.00 124.08 ? 295 ASP E CB    1 
ATOM   5601  C  CG    . ASP B 1 295 ? 378.362 388.251 234.405 1.00 125.24 ? 295 ASP E CG    1 
ATOM   5602  O  OD1   . ASP B 1 295 ? 378.969 389.320 234.628 1.00 125.23 ? 295 ASP E OD1   1 
ATOM   5603  O  OD2   . ASP B 1 295 ? 377.335 387.915 235.029 1.00 126.78 ? 295 ASP E OD2   1 
ATOM   5604  N  N     . ALA B 1 296 ? 381.643 388.676 234.594 1.00 113.20 ? 296 ALA E N     1 
ATOM   5605  C  CA    . ALA B 1 296 ? 382.560 388.637 235.728 1.00 111.73 ? 296 ALA E CA    1 
ATOM   5606  C  C     . ALA B 1 296 ? 381.962 387.879 236.903 1.00 111.90 ? 296 ALA E C     1 
ATOM   5607  O  O     . ALA B 1 296 ? 382.659 387.090 237.554 1.00 114.74 ? 296 ALA E O     1 
ATOM   5608  C  CB    . ALA B 1 296 ? 382.927 390.060 236.150 1.00 111.63 ? 296 ALA E CB    1 
ATOM   5609  N  N     . LYS B 1 297 ? 380.666 388.079 237.162 1.00 107.80 ? 297 LYS E N     1 
ATOM   5610  C  CA    . LYS B 1 297 ? 380.016 387.480 238.325 1.00 108.10 ? 297 LYS E CA    1 
ATOM   5611  C  C     . LYS B 1 297 ? 380.023 385.957 238.272 1.00 109.99 ? 297 LYS E C     1 
ATOM   5612  O  O     . LYS B 1 297 ? 379.938 385.302 239.317 1.00 108.82 ? 297 LYS E O     1 
ATOM   5613  C  CB    . LYS B 1 297 ? 378.580 387.993 238.426 1.00 107.15 ? 297 LYS E CB    1 
ATOM   5614  N  N     . ASN B 1 298 ? 380.121 385.376 237.076 1.00 111.26 ? 298 ASN E N     1 
ATOM   5615  C  CA    . ASN B 1 298 ? 380.169 383.928 236.932 1.00 111.56 ? 298 ASN E CA    1 
ATOM   5616  C  C     . ASN B 1 298 ? 381.535 383.339 237.275 1.00 113.69 ? 298 ASN E C     1 
ATOM   5617  O  O     . ASN B 1 298 ? 381.623 382.131 237.519 1.00 114.99 ? 298 ASN E O     1 
ATOM   5618  C  CB    . ASN B 1 298 ? 379.782 383.558 235.497 1.00 115.64 ? 298 ASN E CB    1 
ATOM   5619  C  CG    . ASN B 1 298 ? 379.661 382.063 235.285 1.00 118.19 ? 298 ASN E CG    1 
ATOM   5620  O  OD1   . ASN B 1 298 ? 380.658 381.365 235.104 1.00 120.59 ? 298 ASN E OD1   1 
ATOM   5621  N  ND2   . ASN B 1 298 ? 378.431 381.563 235.300 1.00 117.26 ? 298 ASN E ND2   1 
ATOM   5622  N  N     . MET B 1 299 ? 382.592 384.151 237.322 1.00 112.86 ? 299 MET E N     1 
ATOM   5623  C  CA    . MET B 1 299 ? 383.942 383.608 237.443 1.00 109.55 ? 299 MET E CA    1 
ATOM   5624  C  C     . MET B 1 299 ? 384.171 382.962 238.802 1.00 113.13 ? 299 MET E C     1 
ATOM   5625  O  O     . MET B 1 299 ? 383.712 383.460 239.833 1.00 117.77 ? 299 MET E O     1 
ATOM   5626  C  CB    . MET B 1 299 ? 384.986 384.707 237.220 1.00 112.35 ? 299 MET E CB    1 
ATOM   5627  C  CG    . MET B 1 299 ? 386.235 384.276 236.446 1.00 114.66 ? 299 MET E CG    1 
ATOM   5628  S  SD    . MET B 1 299 ? 386.018 383.575 234.792 1.00 125.91 ? 299 MET E SD    1 
ATOM   5629  C  CE    . MET B 1 299 ? 384.828 384.694 234.064 1.00 114.45 ? 299 MET E CE    1 
ATOM   5630  N  N     . MET B 1 300 ? 384.911 381.852 238.795 1.00 108.81 ? 300 MET E N     1 
ATOM   5631  C  CA    . MET B 1 300 ? 385.205 381.082 239.996 1.00 109.99 ? 300 MET E CA    1 
ATOM   5632  C  C     . MET B 1 300 ? 386.485 381.530 240.702 1.00 110.27 ? 300 MET E C     1 
ATOM   5633  O  O     . MET B 1 300 ? 386.972 380.806 241.576 1.00 111.14 ? 300 MET E O     1 
ATOM   5634  C  CB    . MET B 1 300 ? 385.300 379.590 239.656 1.00 110.56 ? 300 MET E CB    1 
ATOM   5635  C  CG    . MET B 1 300 ? 384.022 379.004 239.077 1.00 112.68 ? 300 MET E CG    1 
ATOM   5636  S  SD    . MET B 1 300 ? 384.014 377.205 239.104 1.00 120.18 ? 300 MET E SD    1 
ATOM   5637  C  CE    . MET B 1 300 ? 384.875 376.848 237.586 1.00 113.91 ? 300 MET E CE    1 
ATOM   5638  N  N     . ALA B 1 301 ? 387.042 382.687 240.341 1.00 113.96 ? 301 ALA E N     1 
ATOM   5639  C  CA    . ALA B 1 301 ? 388.085 383.356 241.109 1.00 113.56 ? 301 ALA E CA    1 
ATOM   5640  C  C     . ALA B 1 301 ? 387.570 384.724 241.528 1.00 117.22 ? 301 ALA E C     1 
ATOM   5641  O  O     . ALA B 1 301 ? 386.903 385.410 240.748 1.00 117.02 ? 301 ALA E O     1 
ATOM   5642  C  CB    . ALA B 1 301 ? 389.375 383.503 240.301 1.00 112.33 ? 301 ALA E CB    1 
ATOM   5643  N  N     . ALA B 1 302 ? 387.883 385.119 242.763 1.00 131.69 ? 302 ALA E N     1 
ATOM   5644  C  CA    . ALA B 1 302 ? 387.314 386.341 243.320 1.00 133.13 ? 302 ALA E CA    1 
ATOM   5645  C  C     . ALA B 1 302 ? 387.792 387.600 242.608 1.00 131.70 ? 302 ALA E C     1 
ATOM   5646  O  O     . ALA B 1 302 ? 387.113 388.629 242.685 1.00 132.87 ? 302 ALA E O     1 
ATOM   5647  C  CB    . ALA B 1 302 ? 387.644 386.440 244.809 1.00 134.59 ? 302 ALA E CB    1 
ATOM   5648  N  N     . CYS B 1 303 ? 388.932 387.552 241.926 1.00 125.20 ? 303 CYS E N     1 
ATOM   5649  C  CA    . CYS B 1 303 ? 389.445 388.736 241.252 1.00 128.90 ? 303 CYS E CA    1 
ATOM   5650  C  C     . CYS B 1 303 ? 388.558 389.113 240.071 1.00 124.61 ? 303 CYS E C     1 
ATOM   5651  O  O     . CYS B 1 303 ? 388.091 388.252 239.321 1.00 120.98 ? 303 CYS E O     1 
ATOM   5652  C  CB    . CYS B 1 303 ? 390.877 388.496 240.781 1.00 129.47 ? 303 CYS E CB    1 
ATOM   5653  S  SG    . CYS B 1 303 ? 391.054 387.105 239.653 1.00 133.10 ? 303 CYS E SG    1 
ATOM   5654  N  N     . ASP B 1 304 ? 388.327 390.410 239.913 1.00 123.43 ? 304 ASP E N     1 
ATOM   5655  C  CA    . ASP B 1 304 ? 387.497 390.913 238.824 1.00 124.24 ? 304 ASP E CA    1 
ATOM   5656  C  C     . ASP B 1 304 ? 388.286 390.867 237.514 1.00 125.84 ? 304 ASP E C     1 
ATOM   5657  O  O     . ASP B 1 304 ? 389.406 391.386 237.466 1.00 129.65 ? 304 ASP E O     1 
ATOM   5658  C  CB    . ASP B 1 304 ? 387.061 392.346 239.117 1.00 125.21 ? 304 ASP E CB    1 
ATOM   5659  C  CG    . ASP B 1 304 ? 385.879 392.785 238.275 1.00 129.53 ? 304 ASP E CG    1 
ATOM   5660  O  OD1   . ASP B 1 304 ? 385.544 392.092 237.293 1.00 130.88 ? 304 ASP E OD1   1 
ATOM   5661  O  OD2   . ASP B 1 304 ? 385.280 393.832 238.597 1.00 130.72 ? 304 ASP E OD2   1 
ATOM   5662  N  N     . PRO B 1 305 ? 387.763 390.258 236.437 1.00 110.08 ? 305 PRO E N     1 
ATOM   5663  C  CA    . PRO B 1 305 ? 388.477 390.361 235.151 1.00 108.00 ? 305 PRO E CA    1 
ATOM   5664  C  C     . PRO B 1 305 ? 388.591 391.778 234.621 1.00 116.10 ? 305 PRO E C     1 
ATOM   5665  O  O     . PRO B 1 305 ? 389.520 392.060 233.856 1.00 120.85 ? 305 PRO E O     1 
ATOM   5666  C  CB    . PRO B 1 305 ? 387.644 389.483 234.208 1.00 105.83 ? 305 PRO E CB    1 
ATOM   5667  C  CG    . PRO B 1 305 ? 386.918 388.561 235.082 1.00 111.07 ? 305 PRO E CG    1 
ATOM   5668  C  CD    . PRO B 1 305 ? 386.622 389.328 236.322 1.00 113.13 ? 305 PRO E CD    1 
ATOM   5669  N  N     . ARG B 1 306 ? 387.682 392.679 234.997 1.00 124.11 ? 306 ARG E N     1 
ATOM   5670  C  CA    . ARG B 1 306 ? 387.714 394.031 234.454 1.00 122.88 ? 306 ARG E CA    1 
ATOM   5671  C  C     . ARG B 1 306 ? 388.892 394.844 234.970 1.00 121.17 ? 306 ARG E C     1 
ATOM   5672  O  O     . ARG B 1 306 ? 389.307 395.795 234.299 1.00 123.87 ? 306 ARG E O     1 
ATOM   5673  C  CB    . ARG B 1 306 ? 386.411 394.757 234.779 1.00 122.33 ? 306 ARG E CB    1 
ATOM   5674  C  CG    . ARG B 1 306 ? 385.192 394.152 234.101 1.00 122.41 ? 306 ARG E CG    1 
ATOM   5675  C  CD    . ARG B 1 306 ? 384.010 395.107 234.095 1.00 126.91 ? 306 ARG E CD    1 
ATOM   5676  N  NE    . ARG B 1 306 ? 383.464 395.300 235.435 1.00 129.92 ? 306 ARG E NE    1 
ATOM   5677  C  CZ    . ARG B 1 306 ? 382.663 394.451 236.070 1.00 128.34 ? 306 ARG E CZ    1 
ATOM   5678  N  NH1   . ARG B 1 306 ? 382.289 393.299 235.530 1.00 126.55 ? 306 ARG E NH1   1 
ATOM   5679  N  NH2   . ARG B 1 306 ? 382.227 394.763 237.286 1.00 126.12 ? 306 ARG E NH2   1 
ATOM   5680  N  N     . HIS B 1 307 ? 389.429 394.511 236.146 1.00 110.07 ? 307 HIS E N     1 
ATOM   5681  C  CA    . HIS B 1 307 ? 390.577 395.249 236.662 1.00 114.68 ? 307 HIS E CA    1 
ATOM   5682  C  C     . HIS B 1 307 ? 391.797 395.059 235.772 1.00 115.46 ? 307 HIS E C     1 
ATOM   5683  O  O     . HIS B 1 307 ? 392.488 396.030 235.440 1.00 119.42 ? 307 HIS E O     1 
ATOM   5684  C  CB    . HIS B 1 307 ? 390.882 394.807 238.093 1.00 115.66 ? 307 HIS E CB    1 
ATOM   5685  C  CG    . HIS B 1 307 ? 389.803 395.145 239.076 1.00 117.43 ? 307 HIS E CG    1 
ATOM   5686  N  ND1   . HIS B 1 307 ? 389.653 394.476 240.272 1.00 117.39 ? 307 HIS E ND1   1 
ATOM   5687  C  CD2   . HIS B 1 307 ? 388.823 396.079 239.043 1.00 115.03 ? 307 HIS E CD2   1 
ATOM   5688  C  CE1   . HIS B 1 307 ? 388.628 394.983 240.932 1.00 117.08 ? 307 HIS E CE1   1 
ATOM   5689  N  NE2   . HIS B 1 307 ? 388.107 395.957 240.208 1.00 116.86 ? 307 HIS E NE2   1 
ATOM   5690  N  N     . GLY B 1 308 ? 392.071 393.816 235.367 1.00 100.22 ? 308 GLY E N     1 
ATOM   5691  C  CA    . GLY B 1 308 ? 393.141 393.515 234.445 1.00 102.56 ? 308 GLY E CA    1 
ATOM   5692  C  C     . GLY B 1 308 ? 392.647 393.413 233.008 1.00 101.76 ? 308 GLY E C     1 
ATOM   5693  O  O     . GLY B 1 308 ? 391.468 393.578 232.705 1.00 98.03  ? 308 GLY E O     1 
ATOM   5694  N  N     . ARG B 1 309 ? 393.595 393.142 232.119 1.00 116.29 ? 309 ARG E N     1 
ATOM   5695  C  CA    . ARG B 1 309 ? 393.333 392.806 230.728 1.00 110.26 ? 309 ARG E CA    1 
ATOM   5696  C  C     . ARG B 1 309 ? 393.411 391.297 230.546 1.00 108.11 ? 309 ARG E C     1 
ATOM   5697  O  O     . ARG B 1 309 ? 393.942 390.575 231.393 1.00 113.13 ? 309 ARG E O     1 
ATOM   5698  C  CB    . ARG B 1 309 ? 394.332 393.498 229.797 1.00 114.03 ? 309 ARG E CB    1 
ATOM   5699  C  CG    . ARG B 1 309 ? 394.196 395.011 229.752 1.00 115.43 ? 309 ARG E CG    1 
ATOM   5700  C  CD    . ARG B 1 309 ? 395.276 395.651 228.865 1.00 114.94 ? 309 ARG E CD    1 
ATOM   5701  N  NE    . ARG B 1 309 ? 394.801 396.091 227.554 1.00 118.91 ? 309 ARG E NE    1 
ATOM   5702  C  CZ    . ARG B 1 309 ? 393.860 397.002 227.331 1.00 118.03 ? 309 ARG E CZ    1 
ATOM   5703  N  NH1   . ARG B 1 309 ? 393.280 397.670 228.320 1.00 117.07 ? 309 ARG E NH1   1 
ATOM   5704  N  NH2   . ARG B 1 309 ? 393.494 397.260 226.079 1.00 114.80 ? 309 ARG E NH2   1 
ATOM   5705  N  N     . TYR B 1 310 ? 392.956 390.770 229.405 1.00 107.21 ? 310 TYR E N     1 
ATOM   5706  C  CA    . TYR B 1 310 ? 393.004 389.298 229.146 1.00 103.89 ? 310 TYR E CA    1 
ATOM   5707  C  C     . TYR B 1 310 ? 394.232 388.941 228.297 1.00 104.95 ? 310 TYR E C     1 
ATOM   5708  O  O     . TYR B 1 310 ? 394.600 389.754 227.431 1.00 110.20 ? 310 TYR E O     1 
ATOM   5709  C  CB    . TYR B 1 310 ? 391.725 388.815 228.459 1.00 107.56 ? 310 TYR E CB    1 
ATOM   5710  C  CG    . TYR B 1 310 ? 390.584 388.350 229.353 1.00 104.25 ? 310 TYR E CG    1 
ATOM   5711  C  CD1   . TYR B 1 310 ? 390.693 387.196 230.117 1.00 101.36 ? 310 TYR E CD1   1 
ATOM   5712  C  CD2   . TYR B 1 310 ? 389.395 389.064 229.424 1.00 108.29 ? 310 TYR E CD2   1 
ATOM   5713  C  CE1   . TYR B 1 310 ? 389.654 386.765 230.924 1.00 104.74 ? 310 TYR E CE1   1 
ATOM   5714  C  CE2   . TYR B 1 310 ? 388.350 388.647 230.230 1.00 105.47 ? 310 TYR E CE2   1 
ATOM   5715  C  CZ    . TYR B 1 310 ? 388.480 387.495 230.983 1.00 105.82 ? 310 TYR E CZ    1 
ATOM   5716  O  OH    . TYR B 1 310 ? 387.451 387.081 231.777 1.00 107.82 ? 310 TYR E OH    1 
ATOM   5717  N  N     . LEU B 1 311 ? 394.810 387.757 228.518 1.00 98.50  ? 311 LEU E N     1 
ATOM   5718  C  CA    . LEU B 1 311 ? 395.933 387.293 227.660 1.00 96.79  ? 311 LEU E CA    1 
ATOM   5719  C  C     . LEU B 1 311 ? 395.371 386.279 226.659 1.00 99.18  ? 311 LEU E C     1 
ATOM   5720  O  O     . LEU B 1 311 ? 395.165 386.656 225.490 1.00 106.18 ? 311 LEU E O     1 
ATOM   5721  C  CB    . LEU B 1 311 ? 397.017 386.661 228.537 1.00 100.59 ? 311 LEU E CB    1 
ATOM   5722  C  CG    . LEU B 1 311 ? 397.713 387.612 229.509 1.00 98.02  ? 311 LEU E CG    1 
ATOM   5723  C  CD1   . LEU B 1 311 ? 398.659 386.851 230.426 1.00 96.00  ? 311 LEU E CD1   1 
ATOM   5724  C  CD2   . LEU B 1 311 ? 398.463 388.698 228.754 1.00 95.87  ? 311 LEU E CD2   1 
ATOM   5725  N  N     . THR B 1 312 ? 395.053 385.069 227.124 1.00 94.72  ? 312 THR E N     1 
ATOM   5726  C  CA    . THR B 1 312 ? 394.448 384.033 226.252 1.00 93.41  ? 312 THR E CA    1 
ATOM   5727  C  C     . THR B 1 312 ? 393.195 383.477 226.935 1.00 96.12  ? 312 THR E C     1 
ATOM   5728  O  O     . THR B 1 312 ? 393.207 383.373 228.171 1.00 99.10  ? 312 THR E O     1 
ATOM   5729  C  CB    . THR B 1 312 ? 395.471 382.938 225.937 1.00 105.89 ? 312 THR E CB    1 
ATOM   5730  O  OG1   . THR B 1 312 ? 395.899 382.367 227.174 1.00 100.88 ? 312 THR E OG1   1 
ATOM   5731  C  CG2   . THR B 1 312 ? 396.672 383.451 225.173 1.00 113.15 ? 312 THR E CG2   1 
ATOM   5732  N  N     . VAL B 1 313 ? 392.156 383.149 226.163 1.00 105.00 ? 313 VAL E N     1 
ATOM   5733  C  CA    . VAL B 1 313 ? 390.882 382.603 226.722 1.00 103.06 ? 313 VAL E CA    1 
ATOM   5734  C  C     . VAL B 1 313 ? 390.555 381.290 226.001 1.00 101.24 ? 313 VAL E C     1 
ATOM   5735  O  O     . VAL B 1 313 ? 390.812 381.215 224.786 1.00 103.46 ? 313 VAL E O     1 
ATOM   5736  C  CB    . VAL B 1 313 ? 389.740 383.628 226.584 1.00 100.48 ? 313 VAL E CB    1 
ATOM   5737  C  CG1   . VAL B 1 313 ? 388.399 383.069 227.029 1.00 101.69 ? 313 VAL E CG1   1 
ATOM   5738  C  CG2   . VAL B 1 313 ? 390.053 384.931 227.300 1.00 103.11 ? 313 VAL E CG2   1 
ATOM   5739  N  N     . ALA B 1 314 ? 390.027 380.294 226.721 1.00 90.84  ? 314 ALA E N     1 
ATOM   5740  C  CA    . ALA B 1 314 ? 389.694 378.986 226.113 1.00 87.58  ? 314 ALA E CA    1 
ATOM   5741  C  C     . ALA B 1 314 ? 388.223 378.654 226.366 1.00 92.99  ? 314 ALA E C     1 
ATOM   5742  O  O     . ALA B 1 314 ? 387.825 378.599 227.541 1.00 100.11 ? 314 ALA E O     1 
ATOM   5743  C  CB    . ALA B 1 314 ? 390.582 377.910 226.670 1.00 83.94  ? 314 ALA E CB    1 
ATOM   5744  N  N     . ALA B 1 315 ? 387.455 378.434 225.297 1.00 93.68  ? 315 ALA E N     1 
ATOM   5745  C  CA    . ALA B 1 315 ? 386.054 378.054 225.475 1.00 88.01  ? 315 ALA E CA    1 
ATOM   5746  C  C     . ALA B 1 315 ? 385.889 376.646 224.917 1.00 90.08  ? 315 ALA E C     1 
ATOM   5747  O  O     . ALA B 1 315 ? 385.922 376.449 223.697 1.00 95.94  ? 315 ALA E O     1 
ATOM   5748  C  CB    . ALA B 1 315 ? 385.124 379.045 224.790 1.00 84.37  ? 315 ALA E CB    1 
ATOM   5749  N  N     . VAL B 1 316 ? 385.751 375.675 225.818 1.00 91.89  ? 316 VAL E N     1 
ATOM   5750  C  CA    . VAL B 1 316 ? 385.478 374.290 225.454 1.00 87.67  ? 316 VAL E CA    1 
ATOM   5751  C  C     . VAL B 1 316 ? 383.970 374.099 225.551 1.00 93.56  ? 316 VAL E C     1 
ATOM   5752  O  O     . VAL B 1 316 ? 383.406 374.066 226.646 1.00 95.52  ? 316 VAL E O     1 
ATOM   5753  C  CB    . VAL B 1 316 ? 386.231 373.309 226.361 1.00 91.13  ? 316 VAL E CB    1 
ATOM   5754  C  CG1   . VAL B 1 316 ? 386.179 371.898 225.781 1.00 91.11  ? 316 VAL E CG1   1 
ATOM   5755  C  CG2   . VAL B 1 316 ? 387.674 373.764 226.551 1.00 91.91  ? 316 VAL E CG2   1 
ATOM   5756  N  N     . PHE B 1 317 ? 383.323 373.964 224.403 1.00 97.36  ? 317 PHE E N     1 
ATOM   5757  C  CA    . PHE B 1 317 ? 381.881 373.840 224.312 1.00 96.42  ? 317 PHE E CA    1 
ATOM   5758  C  C     . PHE B 1 317 ? 381.502 372.368 224.281 1.00 99.98  ? 317 PHE E C     1 
ATOM   5759  O  O     . PHE B 1 317 ? 382.250 371.544 223.752 1.00 100.74 ? 317 PHE E O     1 
ATOM   5760  C  CB    . PHE B 1 317 ? 381.393 374.536 223.046 1.00 95.83  ? 317 PHE E CB    1 
ATOM   5761  C  CG    . PHE B 1 317 ? 381.390 376.030 223.142 1.00 96.89  ? 317 PHE E CG    1 
ATOM   5762  C  CD1   . PHE B 1 317 ? 382.517 376.753 222.813 1.00 105.23 ? 317 PHE E CD1   1 
ATOM   5763  C  CD2   . PHE B 1 317 ? 380.271 376.710 223.577 1.00 94.27  ? 317 PHE E CD2   1 
ATOM   5764  C  CE1   . PHE B 1 317 ? 382.520 378.124 222.898 1.00 106.60 ? 317 PHE E CE1   1 
ATOM   5765  C  CE2   . PHE B 1 317 ? 380.270 378.084 223.667 1.00 100.32 ? 317 PHE E CE2   1 
ATOM   5766  C  CZ    . PHE B 1 317 ? 381.398 378.791 223.328 1.00 102.68 ? 317 PHE E CZ    1 
ATOM   5767  N  N     . ARG B 1 318 ? 380.341 372.041 224.854 1.00 106.17 ? 318 ARG E N     1 
ATOM   5768  C  CA    . ARG B 1 318 ? 379.853 370.672 224.939 1.00 100.07 ? 318 ARG E CA    1 
ATOM   5769  C  C     . ARG B 1 318 ? 378.380 370.625 224.566 1.00 103.56 ? 318 ARG E C     1 
ATOM   5770  O  O     . ARG B 1 318 ? 377.594 371.485 224.981 1.00 109.09 ? 318 ARG E O     1 
ATOM   5771  C  CB    . ARG B 1 318 ? 380.057 370.104 226.343 1.00 101.98 ? 318 ARG E CB    1 
ATOM   5772  C  CG    . ARG B 1 318 ? 381.490 369.688 226.633 1.00 106.39 ? 318 ARG E CG    1 
ATOM   5773  C  CD    . ARG B 1 318 ? 381.612 368.999 227.981 1.00 108.20 ? 318 ARG E CD    1 
ATOM   5774  N  NE    . ARG B 1 318 ? 380.954 367.697 227.991 1.00 108.45 ? 318 ARG E NE    1 
ATOM   5775  C  CZ    . ARG B 1 318 ? 380.948 366.846 229.011 1.00 109.36 ? 318 ARG E CZ    1 
ATOM   5776  N  NH1   . ARG B 1 318 ? 381.577 367.109 230.148 1.00 108.92 ? 318 ARG E NH1   1 
ATOM   5777  N  NH2   . ARG B 1 318 ? 380.292 365.696 228.888 1.00 109.05 ? 318 ARG E NH2   1 
ATOM   5778  N  N     . GLY B 1 319 ? 378.019 369.596 223.805 1.00 111.44 ? 319 GLY E N     1 
ATOM   5779  C  CA    . GLY B 1 319 ? 376.684 369.403 223.282 1.00 115.11 ? 319 GLY E CA    1 
ATOM   5780  C  C     . GLY B 1 319 ? 376.632 369.587 221.775 1.00 119.27 ? 319 GLY E C     1 
ATOM   5781  O  O     . GLY B 1 319 ? 377.622 369.921 221.119 1.00 117.53 ? 319 GLY E O     1 
ATOM   5782  N  N     . ARG B 1 320 ? 375.449 369.350 221.216 1.00 123.57 ? 320 ARG E N     1 
ATOM   5783  C  CA    . ARG B 1 320 ? 375.197 369.679 219.819 1.00 117.96 ? 320 ARG E CA    1 
ATOM   5784  C  C     . ARG B 1 320 ? 375.074 371.191 219.699 1.00 123.06 ? 320 ARG E C     1 
ATOM   5785  O  O     . ARG B 1 320 ? 374.019 371.761 219.996 1.00 119.90 ? 320 ARG E O     1 
ATOM   5786  C  CB    . ARG B 1 320 ? 373.934 368.981 219.323 1.00 112.46 ? 320 ARG E CB    1 
ATOM   5787  N  N     . MET B 1 321 ? 376.155 371.832 219.257 1.00 131.52 ? 321 MET E N     1 
ATOM   5788  C  CA    . MET B 1 321 ? 376.282 373.285 219.251 1.00 126.12 ? 321 MET E CA    1 
ATOM   5789  C  C     . MET B 1 321 ? 376.840 373.755 217.929 1.00 127.96 ? 321 MET E C     1 
ATOM   5790  O  O     . MET B 1 321 ? 377.667 373.070 217.319 1.00 128.32 ? 321 MET E O     1 
ATOM   5791  C  CB    . MET B 1 321 ? 377.182 373.781 220.382 1.00 121.58 ? 321 MET E CB    1 
ATOM   5792  C  CG    . MET B 1 321 ? 376.711 373.338 221.707 1.00 128.34 ? 321 MET E CG    1 
ATOM   5793  S  SD    . MET B 1 321 ? 377.687 374.007 223.048 1.00 145.88 ? 321 MET E SD    1 
ATOM   5794  C  CE    . MET B 1 321 ? 377.028 375.662 223.134 1.00 133.31 ? 321 MET E CE    1 
ATOM   5795  N  N     . SER B 1 322 ? 376.320 374.860 217.382 1.00 133.32 ? 322 SER E N     1 
ATOM   5796  C  CA    . SER B 1 322 ? 376.766 375.301 216.027 1.00 130.82 ? 322 SER E CA    1 
ATOM   5797  C  C     . SER B 1 322 ? 378.184 375.879 216.085 1.00 138.82 ? 322 SER E C     1 
ATOM   5798  O  O     . SER B 1 322 ? 378.555 376.409 217.150 1.00 146.89 ? 322 SER E O     1 
ATOM   5799  C  CB    . SER B 1 322 ? 375.811 376.284 215.422 1.00 130.10 ? 322 SER E CB    1 
ATOM   5800  O  OG    . SER B 1 322 ? 376.333 376.808 214.211 1.00 132.52 ? 322 SER E OG    1 
ATOM   5801  N  N     . MET B 1 323 ? 378.943 375.788 214.989 1.00 132.45 ? 323 MET E N     1 
ATOM   5802  C  CA    . MET B 1 323 ? 380.361 376.243 214.989 1.00 135.35 ? 323 MET E CA    1 
ATOM   5803  C  C     . MET B 1 323 ? 380.465 377.583 214.262 1.00 135.81 ? 323 MET E C     1 
ATOM   5804  O  O     . MET B 1 323 ? 381.545 377.878 213.723 1.00 139.55 ? 323 MET E O     1 
ATOM   5805  C  CB    . MET B 1 323 ? 381.260 375.231 214.280 1.00 129.17 ? 323 MET E CB    1 
ATOM   5806  C  CG    . MET B 1 323 ? 381.868 374.202 215.208 1.00 134.10 ? 323 MET E CG    1 
ATOM   5807  S  SD    . MET B 1 323 ? 380.600 373.343 216.168 1.00 144.92 ? 323 MET E SD    1 
ATOM   5808  C  CE    . MET B 1 323 ? 379.649 372.587 214.851 1.00 135.41 ? 323 MET E CE    1 
ATOM   5809  N  N     . LYS B 1 324 ? 379.383 378.353 214.258 1.00 117.80 ? 324 LYS E N     1 
ATOM   5810  C  CA    . LYS B 1 324 ? 379.356 379.670 213.580 1.00 121.85 ? 324 LYS E CA    1 
ATOM   5811  C  C     . LYS B 1 324 ? 378.827 380.679 214.593 1.00 125.03 ? 324 LYS E C     1 
ATOM   5812  O  O     . LYS B 1 324 ? 379.424 381.762 214.714 1.00 129.31 ? 324 LYS E O     1 
ATOM   5813  C  CB    . LYS B 1 324 ? 378.443 379.547 212.361 1.00 116.52 ? 324 LYS E CB    1 
ATOM   5814  C  CG    . LYS B 1 324 ? 377.946 380.842 211.740 1.00 126.21 ? 324 LYS E CG    1 
ATOM   5815  C  CD    . LYS B 1 324 ? 376.961 380.615 210.613 1.00 128.13 ? 324 LYS E CD    1 
ATOM   5816  C  CE    . LYS B 1 324 ? 376.258 381.878 210.163 1.00 122.87 ? 324 LYS E CE    1 
ATOM   5817  N  NZ    . LYS B 1 324 ? 377.213 382.895 209.663 1.00 118.66 ? 324 LYS E NZ    1 
ATOM   5818  N  N     . GLU B 1 325 ? 377.775 380.307 215.320 1.00 134.21 ? 325 GLU E N     1 
ATOM   5819  C  CA    . GLU B 1 325 ? 377.193 381.170 216.350 1.00 135.69 ? 325 GLU E CA    1 
ATOM   5820  C  C     . GLU B 1 325 ? 378.138 381.286 217.534 1.00 137.51 ? 325 GLU E C     1 
ATOM   5821  O  O     . GLU B 1 325 ? 378.219 382.358 218.145 1.00 142.76 ? 325 GLU E O     1 
ATOM   5822  C  CB    . GLU B 1 325 ? 375.815 380.699 216.838 1.00 135.49 ? 325 GLU E CB    1 
ATOM   5823  C  CG    . GLU B 1 325 ? 375.706 379.288 217.280 1.00 139.20 ? 325 GLU E CG    1 
ATOM   5824  C  CD    . GLU B 1 325 ? 374.297 378.916 217.735 1.00 140.10 ? 325 GLU E CD    1 
ATOM   5825  O  OE1   . GLU B 1 325 ? 373.405 379.793 217.709 1.00 137.43 ? 325 GLU E OE1   1 
ATOM   5826  O  OE2   . GLU B 1 325 ? 374.088 377.759 218.151 1.00 139.46 ? 325 GLU E OE2   1 
ATOM   5827  N  N     . VAL B 1 326 ? 378.896 380.220 217.840 1.00 125.86 ? 326 VAL E N     1 
ATOM   5828  C  CA    . VAL B 1 326 ? 380.037 380.371 218.747 1.00 128.85 ? 326 VAL E CA    1 
ATOM   5829  C  C     . VAL B 1 326 ? 380.976 381.458 218.239 1.00 134.26 ? 326 VAL E C     1 
ATOM   5830  O  O     . VAL B 1 326 ? 381.320 382.385 218.970 1.00 138.76 ? 326 VAL E O     1 
ATOM   5831  C  CB    . VAL B 1 326 ? 380.786 379.032 218.923 1.00 120.59 ? 326 VAL E CB    1 
ATOM   5832  C  CG1   . VAL B 1 326 ? 382.074 379.230 219.703 1.00 124.00 ? 326 VAL E CG1   1 
ATOM   5833  C  CG2   . VAL B 1 326 ? 379.947 378.013 219.675 1.00 124.31 ? 326 VAL E CG2   1 
ATOM   5834  N  N     . ASP B 1 327 ? 381.351 381.389 216.964 1.00 131.00 ? 327 ASP E N     1 
ATOM   5835  C  CA    . ASP B 1 327 ? 382.365 382.287 216.423 1.00 129.88 ? 327 ASP E CA    1 
ATOM   5836  C  C     . ASP B 1 327 ? 381.862 383.726 216.373 1.00 131.00 ? 327 ASP E C     1 
ATOM   5837  O  O     . ASP B 1 327 ? 382.600 384.660 216.705 1.00 136.24 ? 327 ASP E O     1 
ATOM   5838  C  CB    . ASP B 1 327 ? 382.782 381.811 215.025 1.00 129.75 ? 327 ASP E CB    1 
ATOM   5839  C  CG    . ASP B 1 327 ? 383.966 380.842 215.040 1.00 129.57 ? 327 ASP E CG    1 
ATOM   5840  O  OD1   . ASP B 1 327 ? 384.853 380.941 215.912 1.00 130.39 ? 327 ASP E OD1   1 
ATOM   5841  O  OD2   . ASP B 1 327 ? 384.002 379.960 214.155 1.00 129.86 ? 327 ASP E OD2   1 
ATOM   5842  N  N     . GLU B 1 328 ? 380.606 383.922 215.964 1.00 133.57 ? 328 GLU E N     1 
ATOM   5843  C  CA    . GLU B 1 328 ? 380.022 385.256 215.960 1.00 133.47 ? 328 GLU E CA    1 
ATOM   5844  C  C     . GLU B 1 328 ? 379.932 385.810 217.370 1.00 134.68 ? 328 GLU E C     1 
ATOM   5845  O  O     . GLU B 1 328 ? 380.230 386.983 217.588 1.00 139.12 ? 328 GLU E O     1 
ATOM   5846  C  CB    . GLU B 1 328 ? 378.631 385.275 215.308 1.00 133.61 ? 328 GLU E CB    1 
ATOM   5847  C  CG    . GLU B 1 328 ? 378.617 385.247 213.755 1.00 139.47 ? 328 GLU E CG    1 
ATOM   5848  C  CD    . GLU B 1 328 ? 378.026 383.986 213.116 1.00 143.75 ? 328 GLU E CD    1 
ATOM   5849  O  OE1   . GLU B 1 328 ? 377.248 383.250 213.762 1.00 145.02 ? 328 GLU E OE1   1 
ATOM   5850  O  OE2   . GLU B 1 328 ? 378.352 383.723 211.939 1.00 143.76 ? 328 GLU E OE2   1 
ATOM   5851  N  N     . GLN B 1 329 ? 379.542 384.988 218.348 1.00 126.47 ? 329 GLN E N     1 
ATOM   5852  C  CA    . GLN B 1 329 ? 379.464 385.504 219.708 1.00 129.24 ? 329 GLN E CA    1 
ATOM   5853  C  C     . GLN B 1 329 ? 380.842 385.803 220.283 1.00 129.80 ? 329 GLN E C     1 
ATOM   5854  O  O     . GLN B 1 329 ? 380.985 386.750 221.060 1.00 132.87 ? 329 GLN E O     1 
ATOM   5855  C  CB    . GLN B 1 329 ? 378.693 384.526 220.592 1.00 127.26 ? 329 GLN E CB    1 
ATOM   5856  C  CG    . GLN B 1 329 ? 377.197 384.434 220.273 1.00 126.20 ? 329 GLN E CG    1 
ATOM   5857  C  CD    . GLN B 1 329 ? 376.445 385.731 220.547 1.00 130.80 ? 329 GLN E CD    1 
ATOM   5858  O  OE1   . GLN B 1 329 ? 376.539 386.289 221.640 1.00 129.54 ? 329 GLN E OE1   1 
ATOM   5859  N  NE2   . GLN B 1 329 ? 375.703 386.217 219.556 1.00 135.04 ? 329 GLN E NE2   1 
ATOM   5860  N  N     . MET B 1 330 ? 381.870 385.043 219.902 1.00 118.55 ? 330 MET E N     1 
ATOM   5861  C  CA    . MET B 1 330 ? 383.223 385.407 220.317 1.00 121.20 ? 330 MET E CA    1 
ATOM   5862  C  C     . MET B 1 330 ? 383.663 386.703 219.641 1.00 122.16 ? 330 MET E C     1 
ATOM   5863  O  O     . MET B 1 330 ? 384.374 387.512 220.244 1.00 128.59 ? 330 MET E O     1 
ATOM   5864  C  CB    . MET B 1 330 ? 384.228 384.282 220.032 1.00 116.88 ? 330 MET E CB    1 
ATOM   5865  C  CG    . MET B 1 330 ? 383.879 382.865 220.562 1.00 120.38 ? 330 MET E CG    1 
ATOM   5866  S  SD    . MET B 1 330 ? 384.487 382.373 222.180 1.00 135.55 ? 330 MET E SD    1 
ATOM   5867  C  CE    . MET B 1 330 ? 382.956 382.315 223.099 1.00 125.38 ? 330 MET E CE    1 
ATOM   5868  N  N     . LEU B 1 331 ? 383.253 386.918 218.386 1.00 125.21 ? 331 LEU E N     1 
ATOM   5869  C  CA    . LEU B 1 331 ? 383.498 388.209 217.736 1.00 125.80 ? 331 LEU E CA    1 
ATOM   5870  C  C     . LEU B 1 331 ? 382.806 389.355 218.464 1.00 130.12 ? 331 LEU E C     1 
ATOM   5871  O  O     . LEU B 1 331 ? 383.404 390.416 218.662 1.00 133.50 ? 331 LEU E O     1 
ATOM   5872  C  CB    . LEU B 1 331 ? 383.046 388.195 216.271 1.00 128.02 ? 331 LEU E CB    1 
ATOM   5873  C  CG    . LEU B 1 331 ? 383.168 389.493 215.465 1.00 129.98 ? 331 LEU E CG    1 
ATOM   5874  C  CD1   . LEU B 1 331 ? 384.647 389.877 215.369 1.00 132.25 ? 331 LEU E CD1   1 
ATOM   5875  C  CD2   . LEU B 1 331 ? 382.542 389.413 214.083 1.00 129.34 ? 331 LEU E CD2   1 
ATOM   5876  N  N     . ASN B 1 332 ? 381.539 389.173 218.838 1.00 129.59 ? 332 ASN E N     1 
ATOM   5877  C  CA    . ASN B 1 332 ? 380.840 390.209 219.601 1.00 128.27 ? 332 ASN E CA    1 
ATOM   5878  C  C     . ASN B 1 332 ? 381.508 390.446 220.945 1.00 126.94 ? 332 ASN E C     1 
ATOM   5879  O  O     . ASN B 1 332 ? 381.608 391.590 221.399 1.00 129.05 ? 332 ASN E O     1 
ATOM   5880  C  CB    . ASN B 1 332 ? 379.354 389.873 219.796 1.00 128.01 ? 332 ASN E CB    1 
ATOM   5881  C  CG    . ASN B 1 332 ? 378.680 389.371 218.537 1.00 130.13 ? 332 ASN E CG    1 
ATOM   5882  O  OD1   . ASN B 1 332 ? 379.257 389.414 217.452 1.00 128.88 ? 332 ASN E OD1   1 
ATOM   5883  N  ND2   . ASN B 1 332 ? 377.458 388.866 218.680 1.00 129.33 ? 332 ASN E ND2   1 
ATOM   5884  N  N     . VAL B 1 333 ? 381.986 389.381 221.588 1.00 118.28 ? 333 VAL E N     1 
ATOM   5885  C  CA    . VAL B 1 333 ? 382.687 389.535 222.859 1.00 120.62 ? 333 VAL E CA    1 
ATOM   5886  C  C     . VAL B 1 333 ? 383.977 390.319 222.658 1.00 123.71 ? 333 VAL E C     1 
ATOM   5887  O  O     . VAL B 1 333 ? 384.307 391.208 223.446 1.00 131.55 ? 333 VAL E O     1 
ATOM   5888  C  CB    . VAL B 1 333 ? 382.960 388.160 223.495 1.00 120.41 ? 333 VAL E CB    1 
ATOM   5889  C  CG1   . VAL B 1 333 ? 383.974 388.287 224.636 1.00 121.37 ? 333 VAL E CG1   1 
ATOM   5890  C  CG2   . VAL B 1 333 ? 381.661 387.537 224.005 1.00 122.83 ? 333 VAL E CG2   1 
ATOM   5891  N  N     . GLN B 1 334 ? 384.739 389.981 221.619 1.00 122.03 ? 334 GLN E N     1 
ATOM   5892  C  CA    . GLN B 1 334 ? 386.008 390.660 221.393 1.00 120.93 ? 334 GLN E CA    1 
ATOM   5893  C  C     . GLN B 1 334 ? 385.787 392.118 221.014 1.00 120.13 ? 334 GLN E C     1 
ATOM   5894  O  O     . GLN B 1 334 ? 386.553 392.993 221.427 1.00 124.44 ? 334 GLN E O     1 
ATOM   5895  C  CB    . GLN B 1 334 ? 386.809 389.926 220.314 1.00 122.00 ? 334 GLN E CB    1 
ATOM   5896  C  CG    . GLN B 1 334 ? 387.486 388.641 220.805 1.00 120.25 ? 334 GLN E CG    1 
ATOM   5897  C  CD    . GLN B 1 334 ? 388.665 388.205 219.947 1.00 118.85 ? 334 GLN E CD    1 
ATOM   5898  O  OE1   . GLN B 1 334 ? 389.691 387.773 220.471 1.00 114.31 ? 334 GLN E OE1   1 
ATOM   5899  N  NE2   . GLN B 1 334 ? 388.515 388.287 218.626 1.00 120.39 ? 334 GLN E NE2   1 
ATOM   5900  N  N     . ASN B 1 335 ? 384.738 392.398 220.239 1.00 123.00 ? 335 ASN E N     1 
ATOM   5901  C  CA    . ASN B 1 335 ? 384.436 393.776 219.868 1.00 125.69 ? 335 ASN E CA    1 
ATOM   5902  C  C     . ASN B 1 335 ? 383.961 394.586 221.069 1.00 126.21 ? 335 ASN E C     1 
ATOM   5903  O  O     . ASN B 1 335 ? 384.372 395.738 221.247 1.00 127.07 ? 335 ASN E O     1 
ATOM   5904  C  CB    . ASN B 1 335 ? 383.386 393.796 218.758 1.00 129.68 ? 335 ASN E CB    1 
ATOM   5905  C  CG    . ASN B 1 335 ? 383.877 393.141 217.481 1.00 130.07 ? 335 ASN E CG    1 
ATOM   5906  O  OD1   . ASN B 1 335 ? 385.069 392.882 217.321 1.00 126.02 ? 335 ASN E OD1   1 
ATOM   5907  N  ND2   . ASN B 1 335 ? 382.955 392.866 216.564 1.00 130.12 ? 335 ASN E ND2   1 
ATOM   5908  N  N     . LYS B 1 336 ? 383.099 394.005 221.907 1.00 113.51 ? 336 LYS E N     1 
ATOM   5909  C  CA    . LYS B 1 336 ? 382.566 394.737 223.050 1.00 111.32 ? 336 LYS E CA    1 
ATOM   5910  C  C     . LYS B 1 336 ? 383.616 394.923 224.139 1.00 114.25 ? 336 LYS E C     1 
ATOM   5911  O  O     . LYS B 1 336 ? 383.708 396.001 224.736 1.00 111.75 ? 336 LYS E O     1 
ATOM   5912  C  CB    . LYS B 1 336 ? 381.347 394.006 223.612 1.00 105.29 ? 336 LYS E CB    1 
ATOM   5913  N  N     . ASN B 1 337 ? 384.413 393.886 224.399 1.00 136.09 ? 337 ASN E N     1 
ATOM   5914  C  CA    . ASN B 1 337 ? 385.397 393.853 225.474 1.00 135.36 ? 337 ASN E CA    1 
ATOM   5915  C  C     . ASN B 1 337 ? 386.823 394.017 224.958 1.00 134.18 ? 337 ASN E C     1 
ATOM   5916  O  O     . ASN B 1 337 ? 387.761 393.501 225.576 1.00 134.17 ? 337 ASN E O     1 
ATOM   5917  C  CB    . ASN B 1 337 ? 385.266 392.542 226.250 1.00 135.93 ? 337 ASN E CB    1 
ATOM   5918  C  CG    . ASN B 1 337 ? 383.891 392.358 226.855 1.00 132.26 ? 337 ASN E CG    1 
ATOM   5919  O  OD1   . ASN B 1 337 ? 382.962 393.107 226.552 1.00 128.50 ? 337 ASN E OD1   1 
ATOM   5920  N  ND2   . ASN B 1 337 ? 383.751 391.352 227.711 1.00 132.59 ? 337 ASN E ND2   1 
ATOM   5921  N  N     . SER B 1 338 ? 387.001 394.722 223.832 1.00 133.31 ? 338 SER E N     1 
ATOM   5922  C  CA    . SER B 1 338 ? 388.336 394.919 223.272 1.00 134.82 ? 338 SER E CA    1 
ATOM   5923  C  C     . SER B 1 338 ? 389.246 395.649 224.248 1.00 133.88 ? 338 SER E C     1 
ATOM   5924  O  O     . SER B 1 338 ? 390.429 395.307 224.371 1.00 132.47 ? 338 SER E O     1 
ATOM   5925  C  CB    . SER B 1 338 ? 388.248 395.699 221.959 1.00 134.76 ? 338 SER E CB    1 
ATOM   5926  O  OG    . SER B 1 338 ? 387.580 396.934 222.145 1.00 133.20 ? 338 SER E OG    1 
ATOM   5927  N  N     . SER B 1 339 ? 388.694 396.609 224.994 1.00 126.51 ? 339 SER E N     1 
ATOM   5928  C  CA    . SER B 1 339 ? 389.445 397.301 226.034 1.00 123.25 ? 339 SER E CA    1 
ATOM   5929  C  C     . SER B 1 339 ? 389.951 396.359 227.121 1.00 115.66 ? 339 SER E C     1 
ATOM   5930  O  O     . SER B 1 339 ? 390.915 396.701 227.812 1.00 114.02 ? 339 SER E O     1 
ATOM   5931  C  CB    . SER B 1 339 ? 388.572 398.385 226.668 1.00 121.85 ? 339 SER E CB    1 
ATOM   5932  O  OG    . SER B 1 339 ? 387.968 399.196 225.676 1.00 125.33 ? 339 SER E OG    1 
ATOM   5933  N  N     . TYR B 1 340 ? 389.323 395.195 227.292 1.00 111.69 ? 340 TYR E N     1 
ATOM   5934  C  CA    . TYR B 1 340 ? 389.754 394.188 228.248 1.00 113.02 ? 340 TYR E CA    1 
ATOM   5935  C  C     . TYR B 1 340 ? 390.703 393.147 227.664 1.00 113.70 ? 340 TYR E C     1 
ATOM   5936  O  O     . TYR B 1 340 ? 391.147 392.274 228.413 1.00 118.91 ? 340 TYR E O     1 
ATOM   5937  C  CB    . TYR B 1 340 ? 388.528 393.484 228.840 1.00 109.87 ? 340 TYR E CB    1 
ATOM   5938  C  CG    . TYR B 1 340 ? 387.580 394.419 229.557 1.00 112.27 ? 340 TYR E CG    1 
ATOM   5939  C  CD1   . TYR B 1 340 ? 387.965 395.071 230.719 1.00 113.93 ? 340 TYR E CD1   1 
ATOM   5940  C  CD2   . TYR B 1 340 ? 386.302 394.655 229.069 1.00 113.00 ? 340 TYR E CD2   1 
ATOM   5941  C  CE1   . TYR B 1 340 ? 387.105 395.928 231.376 1.00 116.86 ? 340 TYR E CE1   1 
ATOM   5942  C  CE2   . TYR B 1 340 ? 385.436 395.509 229.719 1.00 115.21 ? 340 TYR E CE2   1 
ATOM   5943  C  CZ    . TYR B 1 340 ? 385.842 396.143 230.872 1.00 118.04 ? 340 TYR E CZ    1 
ATOM   5944  O  OH    . TYR B 1 340 ? 384.981 396.995 231.522 1.00 116.77 ? 340 TYR E OH    1 
ATOM   5945  N  N     . PHE B 1 341 ? 391.036 393.216 226.368 1.00 119.27 ? 341 PHE E N     1 
ATOM   5946  C  CA    . PHE B 1 341 ? 391.944 392.269 225.721 1.00 117.49 ? 341 PHE E CA    1 
ATOM   5947  C  C     . PHE B 1 341 ? 393.239 392.964 225.323 1.00 118.70 ? 341 PHE E C     1 
ATOM   5948  O  O     . PHE B 1 341 ? 393.220 394.081 224.798 1.00 130.08 ? 341 PHE E O     1 
ATOM   5949  C  CB    . PHE B 1 341 ? 391.305 391.636 224.481 1.00 117.18 ? 341 PHE E CB    1 
ATOM   5950  C  CG    . PHE B 1 341 ? 390.321 390.544 224.793 1.00 118.14 ? 341 PHE E CG    1 
ATOM   5951  C  CD1   . PHE B 1 341 ? 390.759 389.274 225.121 1.00 117.17 ? 341 PHE E CD1   1 
ATOM   5952  C  CD2   . PHE B 1 341 ? 388.961 390.780 224.738 1.00 117.51 ? 341 PHE E CD2   1 
ATOM   5953  C  CE1   . PHE B 1 341 ? 389.860 388.267 225.404 1.00 116.95 ? 341 PHE E CE1   1 
ATOM   5954  C  CE2   . PHE B 1 341 ? 388.056 389.777 225.020 1.00 114.31 ? 341 PHE E CE2   1 
ATOM   5955  C  CZ    . PHE B 1 341 ? 388.507 388.518 225.351 1.00 117.52 ? 341 PHE E CZ    1 
ATOM   5956  N  N     . VAL B 1 342 ? 394.363 392.292 225.572 1.00 96.81  ? 342 VAL E N     1 
ATOM   5957  C  CA    . VAL B 1 342 ? 395.665 392.842 225.208 1.00 102.21 ? 342 VAL E CA    1 
ATOM   5958  C  C     . VAL B 1 342 ? 395.788 392.884 223.691 1.00 106.79 ? 342 VAL E C     1 
ATOM   5959  O  O     . VAL B 1 342 ? 395.438 391.923 222.994 1.00 103.58 ? 342 VAL E O     1 
ATOM   5960  C  CB    . VAL B 1 342 ? 396.805 392.024 225.839 1.00 103.37 ? 342 VAL E CB    1 
ATOM   5961  C  CG1   . VAL B 1 342 ? 396.687 392.029 227.355 1.00 104.71 ? 342 VAL E CG1   1 
ATOM   5962  C  CG2   . VAL B 1 342 ? 396.859 390.590 225.295 1.00 107.41 ? 342 VAL E CG2   1 
ATOM   5963  N  N     . GLU B 1 343 ? 396.285 394.009 223.171 1.00 125.62 ? 343 GLU E N     1 
ATOM   5964  C  CA    . GLU B 1 343 ? 396.352 394.189 221.725 1.00 122.62 ? 343 GLU E CA    1 
ATOM   5965  C  C     . GLU B 1 343 ? 397.482 393.381 221.094 1.00 122.40 ? 343 GLU E C     1 
ATOM   5966  O  O     . GLU B 1 343 ? 397.385 393.005 219.921 1.00 123.86 ? 343 GLU E O     1 
ATOM   5967  C  CB    . GLU B 1 343 ? 396.490 395.682 221.391 1.00 123.50 ? 343 GLU E CB    1 
ATOM   5968  C  CG    . GLU B 1 343 ? 397.908 396.306 221.420 1.00 129.04 ? 343 GLU E CG    1 
ATOM   5969  C  CD    . GLU B 1 343 ? 398.685 396.094 222.720 1.00 133.60 ? 343 GLU E CD    1 
ATOM   5970  O  OE1   . GLU B 1 343 ? 398.159 395.478 223.670 1.00 133.42 ? 343 GLU E OE1   1 
ATOM   5971  O  OE2   . GLU B 1 343 ? 399.845 396.553 222.786 1.00 128.59 ? 343 GLU E OE2   1 
ATOM   5972  N  N     . TRP B 1 344 ? 398.553 393.102 221.840 1.00 100.85 ? 344 TRP E N     1 
ATOM   5973  C  CA    . TRP B 1 344 ? 399.693 392.400 221.257 1.00 99.21  ? 344 TRP E CA    1 
ATOM   5974  C  C     . TRP B 1 344 ? 399.412 390.924 220.997 1.00 101.82 ? 344 TRP E C     1 
ATOM   5975  O  O     . TRP B 1 344 ? 400.215 390.280 220.313 1.00 101.98 ? 344 TRP E O     1 
ATOM   5976  C  CB    . TRP B 1 344 ? 400.941 392.561 222.138 1.00 92.94  ? 344 TRP E CB    1 
ATOM   5977  C  CG    . TRP B 1 344 ? 400.819 392.054 223.541 1.00 91.79  ? 344 TRP E CG    1 
ATOM   5978  C  CD1   . TRP B 1 344 ? 400.387 392.753 224.629 1.00 94.96  ? 344 TRP E CD1   1 
ATOM   5979  C  CD2   . TRP B 1 344 ? 401.155 390.747 224.012 1.00 94.41  ? 344 TRP E CD2   1 
ATOM   5980  N  NE1   . TRP B 1 344 ? 400.421 391.959 225.746 1.00 97.70  ? 344 TRP E NE1   1 
ATOM   5981  C  CE2   . TRP B 1 344 ? 400.890 390.721 225.394 1.00 99.68  ? 344 TRP E CE2   1 
ATOM   5982  C  CE3   . TRP B 1 344 ? 401.650 389.594 223.398 1.00 99.08  ? 344 TRP E CE3   1 
ATOM   5983  C  CZ2   . TRP B 1 344 ? 401.101 389.588 226.172 1.00 99.70  ? 344 TRP E CZ2   1 
ATOM   5984  C  CZ3   . TRP B 1 344 ? 401.856 388.470 224.172 1.00 104.33 ? 344 TRP E CZ3   1 
ATOM   5985  C  CH2   . TRP B 1 344 ? 401.583 388.475 225.544 1.00 100.75 ? 344 TRP E CH2   1 
ATOM   5986  N  N     . ILE B 1 345 ? 398.318 390.378 221.525 1.00 103.01 ? 345 ILE E N     1 
ATOM   5987  C  CA    . ILE B 1 345 ? 397.724 389.139 221.031 1.00 94.92  ? 345 ILE E CA    1 
ATOM   5988  C  C     . ILE B 1 345 ? 396.567 389.541 220.112 1.00 98.29  ? 345 ILE E C     1 
ATOM   5989  O  O     . ILE B 1 345 ? 395.573 390.094 220.610 1.00 101.41 ? 345 ILE E O     1 
ATOM   5990  C  CB    . ILE B 1 345 ? 397.233 388.242 222.175 1.00 89.50  ? 345 ILE E CB    1 
ATOM   5991  C  CG1   . ILE B 1 345 ? 398.420 387.676 222.962 1.00 93.87  ? 345 ILE E CG1   1 
ATOM   5992  C  CG2   . ILE B 1 345 ? 396.374 387.093 221.628 1.00 97.36  ? 345 ILE E CG2   1 
ATOM   5993  C  CD1   . ILE B 1 345 ? 398.071 387.178 224.353 1.00 103.20 ? 345 ILE E CD1   1 
ATOM   5994  N  N     . PRO B 1 346 ? 396.643 389.301 218.794 1.00 94.17  ? 346 PRO E N     1 
ATOM   5995  C  CA    . PRO B 1 346 ? 395.567 389.827 217.936 1.00 100.18 ? 346 PRO E CA    1 
ATOM   5996  C  C     . PRO B 1 346 ? 394.252 389.098 218.117 1.00 101.87 ? 346 PRO E C     1 
ATOM   5997  O  O     . PRO B 1 346 ? 393.196 389.742 218.142 1.00 103.11 ? 346 PRO E O     1 
ATOM   5998  C  CB    . PRO B 1 346 ? 396.133 389.646 216.524 1.00 102.22 ? 346 PRO E CB    1 
ATOM   5999  C  CG    . PRO B 1 346 ? 396.999 388.469 216.635 1.00 102.74 ? 346 PRO E CG    1 
ATOM   6000  C  CD    . PRO B 1 346 ? 397.610 388.519 217.999 1.00 93.95  ? 346 PRO E CD    1 
ATOM   6001  N  N     . ASN B 1 347 ? 394.290 387.772 218.234 1.00 103.12 ? 347 ASN E N     1 
ATOM   6002  C  CA    . ASN B 1 347 ? 393.130 386.953 218.556 1.00 103.08 ? 347 ASN E CA    1 
ATOM   6003  C  C     . ASN B 1 347 ? 393.457 386.129 219.790 1.00 105.34 ? 347 ASN E C     1 
ATOM   6004  O  O     . ASN B 1 347 ? 394.426 385.365 219.791 1.00 108.53 ? 347 ASN E O     1 
ATOM   6005  C  CB    . ASN B 1 347 ? 392.750 386.041 217.390 1.00 106.90 ? 347 ASN E CB    1 
ATOM   6006  C  CG    . ASN B 1 347 ? 391.377 385.424 217.563 1.00 113.89 ? 347 ASN E CG    1 
ATOM   6007  O  OD1   . ASN B 1 347 ? 391.181 384.552 218.408 1.00 116.95 ? 347 ASN E OD1   1 
ATOM   6008  N  ND2   . ASN B 1 347 ? 390.416 385.879 216.766 1.00 112.75 ? 347 ASN E ND2   1 
ATOM   6009  N  N     . ASN B 1 348 ? 392.639 386.281 220.829 1.00 116.63 ? 348 ASN E N     1 
ATOM   6010  C  CA    . ASN B 1 348 ? 392.904 385.700 222.137 1.00 118.27 ? 348 ASN E CA    1 
ATOM   6011  C  C     . ASN B 1 348 ? 392.163 384.390 222.379 1.00 118.04 ? 348 ASN E C     1 
ATOM   6012  O  O     . ASN B 1 348 ? 392.439 383.722 223.380 1.00 122.56 ? 348 ASN E O     1 
ATOM   6013  C  CB    . ASN B 1 348 ? 392.508 386.698 223.231 1.00 118.99 ? 348 ASN E CB    1 
ATOM   6014  C  CG    . ASN B 1 348 ? 393.033 388.095 222.963 1.00 121.90 ? 348 ASN E CG    1 
ATOM   6015  O  OD1   . ASN B 1 348 ? 392.445 388.848 222.187 1.00 119.66 ? 348 ASN E OD1   1 
ATOM   6016  N  ND2   . ASN B 1 348 ? 394.128 388.457 223.618 1.00 123.17 ? 348 ASN E ND2   1 
ATOM   6017  N  N     . VAL B 1 349 ? 391.245 384.001 221.496 1.00 108.79 ? 349 VAL E N     1 
ATOM   6018  C  CA    . VAL B 1 349 ? 390.274 382.945 221.764 1.00 103.69 ? 349 VAL E CA    1 
ATOM   6019  C  C     . VAL B 1 349 ? 390.757 381.640 221.144 1.00 103.52 ? 349 VAL E C     1 
ATOM   6020  O  O     . VAL B 1 349 ? 391.161 381.609 219.975 1.00 106.22 ? 349 VAL E O     1 
ATOM   6021  C  CB    . VAL B 1 349 ? 388.884 383.345 221.237 1.00 105.29 ? 349 VAL E CB    1 
ATOM   6022  C  CG1   . VAL B 1 349 ? 387.902 382.168 221.192 1.00 110.64 ? 349 VAL E CG1   1 
ATOM   6023  C  CG2   . VAL B 1 349 ? 388.303 384.434 222.117 1.00 99.36  ? 349 VAL E CG2   1 
ATOM   6024  N  N     . LYS B 1 350 ? 390.711 380.566 221.936 1.00 96.58  ? 350 LYS E N     1 
ATOM   6025  C  CA    . LYS B 1 350 ? 390.890 379.193 221.471 1.00 94.91  ? 350 LYS E CA    1 
ATOM   6026  C  C     . LYS B 1 350 ? 389.554 378.481 221.670 1.00 98.12  ? 350 LYS E C     1 
ATOM   6027  O  O     . LYS B 1 350 ? 389.129 378.237 222.808 1.00 104.28 ? 350 LYS E O     1 
ATOM   6028  C  CB    . LYS B 1 350 ? 392.027 378.500 222.225 1.00 92.81  ? 350 LYS E CB    1 
ATOM   6029  C  CG    . LYS B 1 350 ? 392.107 376.970 222.094 1.00 91.41  ? 350 LYS E CG    1 
ATOM   6030  C  CD    . LYS B 1 350 ? 392.074 376.505 220.638 1.00 98.84  ? 350 LYS E CD    1 
ATOM   6031  C  CE    . LYS B 1 350 ? 392.343 375.015 220.511 1.00 101.81 ? 350 LYS E CE    1 
ATOM   6032  N  NZ    . LYS B 1 350 ? 392.132 374.532 219.117 1.00 101.33 ? 350 LYS E NZ    1 
ATOM   6033  N  N     . THR B 1 351 ? 388.893 378.161 220.563 1.00 114.88 ? 351 THR E N     1 
ATOM   6034  C  CA    . THR B 1 351 ? 387.592 377.510 220.574 1.00 114.54 ? 351 THR E CA    1 
ATOM   6035  C  C     . THR B 1 351 ? 387.772 376.003 220.472 1.00 112.27 ? 351 THR E C     1 
ATOM   6036  O  O     . THR B 1 351 ? 388.656 375.521 219.757 1.00 114.81 ? 351 THR E O     1 
ATOM   6037  C  CB    . THR B 1 351 ? 386.729 378.011 219.415 1.00 115.39 ? 351 THR E CB    1 
ATOM   6038  O  OG1   . THR B 1 351 ? 386.617 379.437 219.481 1.00 117.12 ? 351 THR E OG1   1 
ATOM   6039  C  CG2   . THR B 1 351 ? 385.335 377.395 219.463 1.00 114.20 ? 351 THR E CG2   1 
ATOM   6040  N  N     . ALA B 1 352 ? 386.940 375.263 221.203 1.00 99.26  ? 352 ALA E N     1 
ATOM   6041  C  CA    . ALA B 1 352 ? 386.851 373.819 221.059 1.00 93.62  ? 352 ALA E CA    1 
ATOM   6042  C  C     . ALA B 1 352 ? 385.390 373.430 221.189 1.00 94.68  ? 352 ALA E C     1 
ATOM   6043  O  O     . ALA B 1 352 ? 384.636 374.103 221.892 1.00 101.45 ? 352 ALA E O     1 
ATOM   6044  C  CB    . ALA B 1 352 ? 387.694 373.092 222.111 1.00 97.15  ? 352 ALA E CB    1 
ATOM   6045  N  N     . VAL B 1 353 ? 384.994 372.354 220.510 1.00 93.50  ? 353 VAL E N     1 
ATOM   6046  C  CA    . VAL B 1 353 ? 383.613 371.882 220.505 1.00 96.05  ? 353 VAL E CA    1 
ATOM   6047  C  C     . VAL B 1 353 ? 383.617 370.367 220.643 1.00 105.06 ? 353 VAL E C     1 
ATOM   6048  O  O     . VAL B 1 353 ? 384.421 369.678 220.004 1.00 111.88 ? 353 VAL E O     1 
ATOM   6049  C  CB    . VAL B 1 353 ? 382.870 372.310 219.221 1.00 93.11  ? 353 VAL E CB    1 
ATOM   6050  C  CG1   . VAL B 1 353 ? 381.480 371.667 219.162 1.00 94.62  ? 353 VAL E CG1   1 
ATOM   6051  C  CG2   . VAL B 1 353 ? 382.795 373.834 219.130 1.00 96.32  ? 353 VAL E CG2   1 
ATOM   6052  N  N     . CYS B 1 354 ? 382.719 369.854 221.486 1.00 109.10 ? 354 CYS E N     1 
ATOM   6053  C  CA    . CYS B 1 354 ? 382.515 368.428 221.694 1.00 105.15 ? 354 CYS E CA    1 
ATOM   6054  C  C     . CYS B 1 354 ? 381.027 368.128 221.584 1.00 107.95 ? 354 CYS E C     1 
ATOM   6055  O  O     . CYS B 1 354 ? 380.192 368.924 222.022 1.00 110.07 ? 354 CYS E O     1 
ATOM   6056  C  CB    . CYS B 1 354 ? 383.046 367.985 223.061 1.00 105.21 ? 354 CYS E CB    1 
ATOM   6057  S  SG    . CYS B 1 354 ? 382.727 366.255 223.463 1.00 111.87 ? 354 CYS E SG    1 
ATOM   6058  N  N     . ASP B 1 355 ? 380.701 366.975 221.001 1.00 109.21 ? 355 ASP E N     1 
ATOM   6059  C  CA    . ASP B 1 355 ? 379.313 366.667 220.677 1.00 109.35 ? 355 ASP E CA    1 
ATOM   6060  C  C     . ASP B 1 355 ? 378.502 366.227 221.890 1.00 106.15 ? 355 ASP E C     1 
ATOM   6061  O  O     . ASP B 1 355 ? 377.298 366.499 221.949 1.00 112.80 ? 355 ASP E O     1 
ATOM   6062  C  CB    . ASP B 1 355 ? 379.261 365.576 219.606 1.00 113.46 ? 355 ASP E CB    1 
ATOM   6063  C  CG    . ASP B 1 355 ? 379.818 366.037 218.269 1.00 115.49 ? 355 ASP E CG    1 
ATOM   6064  O  OD1   . ASP B 1 355 ? 379.776 367.251 217.981 1.00 115.47 ? 355 ASP E OD1   1 
ATOM   6065  O  OD2   . ASP B 1 355 ? 380.303 365.178 217.504 1.00 110.53 ? 355 ASP E OD2   1 
ATOM   6066  N  N     . ILE B 1 356 ? 379.124 365.560 222.855 1.00 97.79  ? 356 ILE E N     1 
ATOM   6067  C  CA    . ILE B 1 356 ? 378.408 364.882 223.932 1.00 101.47 ? 356 ILE E CA    1 
ATOM   6068  C  C     . ILE B 1 356 ? 378.298 365.849 225.112 1.00 103.72 ? 356 ILE E C     1 
ATOM   6069  O  O     . ILE B 1 356 ? 379.336 366.216 225.684 1.00 105.31 ? 356 ILE E O     1 
ATOM   6070  C  CB    . ILE B 1 356 ? 379.111 363.586 224.360 1.00 107.49 ? 356 ILE E CB    1 
ATOM   6071  C  CG1   . ILE B 1 356 ? 379.752 362.838 223.172 1.00 106.05 ? 356 ILE E CG1   1 
ATOM   6072  C  CG2   . ILE B 1 356 ? 378.138 362.677 225.115 1.00 110.79 ? 356 ILE E CG2   1 
ATOM   6073  C  CD1   . ILE B 1 356 ? 378.805 362.481 222.025 1.00 110.66 ? 356 ILE E CD1   1 
ATOM   6074  N  N     . PRO B 1 357 ? 377.094 366.276 225.518 1.00 103.59 ? 357 PRO E N     1 
ATOM   6075  C  CA    . PRO B 1 357 ? 376.994 367.170 226.682 1.00 105.24 ? 357 PRO E CA    1 
ATOM   6076  C  C     . PRO B 1 357 ? 376.951 366.376 227.975 1.00 106.78 ? 357 PRO E C     1 
ATOM   6077  O  O     . PRO B 1 357 ? 376.764 365.150 227.942 1.00 110.83 ? 357 PRO E O     1 
ATOM   6078  C  CB    . PRO B 1 357 ? 375.673 367.909 226.441 1.00 110.32 ? 357 PRO E CB    1 
ATOM   6079  C  CG    . PRO B 1 357 ? 374.839 366.916 225.755 1.00 105.49 ? 357 PRO E CG    1 
ATOM   6080  C  CD    . PRO B 1 357 ? 375.754 366.048 224.935 1.00 103.09 ? 357 PRO E CD    1 
ATOM   6081  N  N     . PRO B 1 358 ? 377.110 367.026 229.132 1.00 114.58 ? 358 PRO E N     1 
ATOM   6082  C  CA    . PRO B 1 358 ? 377.052 366.311 230.410 1.00 120.70 ? 358 PRO E CA    1 
ATOM   6083  C  C     . PRO B 1 358 ? 375.676 366.331 231.060 1.00 125.91 ? 358 PRO E C     1 
ATOM   6084  O  O     . PRO B 1 358 ? 374.844 367.204 230.807 1.00 124.37 ? 358 PRO E O     1 
ATOM   6085  C  CB    . PRO B 1 358 ? 378.060 367.092 231.261 1.00 120.26 ? 358 PRO E CB    1 
ATOM   6086  C  CG    . PRO B 1 358 ? 377.877 368.507 230.802 1.00 120.05 ? 358 PRO E CG    1 
ATOM   6087  C  CD    . PRO B 1 358 ? 377.417 368.454 229.351 1.00 116.98 ? 358 PRO E CD    1 
ATOM   6088  N  N     . ARG B 1 359 ? 375.448 365.333 231.922 1.00 133.50 ? 359 ARG E N     1 
ATOM   6089  C  CA    . ARG B 1 359 ? 374.312 365.214 232.846 1.00 133.60 ? 359 ARG E CA    1 
ATOM   6090  C  C     . ARG B 1 359 ? 372.956 365.138 232.144 1.00 130.97 ? 359 ARG E C     1 
ATOM   6091  O  O     . ARG B 1 359 ? 371.915 365.178 232.815 1.00 132.57 ? 359 ARG E O     1 
ATOM   6092  C  CB    . ARG B 1 359 ? 374.297 366.374 233.857 1.00 134.81 ? 359 ARG E CB    1 
ATOM   6093  C  CG    . ARG B 1 359 ? 375.228 366.148 235.040 1.00 131.34 ? 359 ARG E CG    1 
ATOM   6094  C  CD    . ARG B 1 359 ? 375.860 367.459 235.505 1.00 135.17 ? 359 ARG E CD    1 
ATOM   6095  N  NE    . ARG B 1 359 ? 377.182 367.607 234.911 1.00 136.96 ? 359 ARG E NE    1 
ATOM   6096  C  CZ    . ARG B 1 359 ? 378.086 368.519 235.240 1.00 134.85 ? 359 ARG E CZ    1 
ATOM   6097  N  NH1   . ARG B 1 359 ? 377.865 369.415 236.192 1.00 135.71 ? 359 ARG E NH1   1 
ATOM   6098  N  NH2   . ARG B 1 359 ? 379.235 368.548 234.574 1.00 131.68 ? 359 ARG E NH2   1 
ATOM   6099  N  N     . GLY B 1 360 ? 372.926 364.977 230.824 1.00 135.46 ? 360 GLY E N     1 
ATOM   6100  C  CA    . GLY B 1 360 ? 371.704 365.119 230.068 1.00 141.49 ? 360 GLY E CA    1 
ATOM   6101  C  C     . GLY B 1 360 ? 371.313 366.544 229.740 1.00 144.76 ? 360 GLY E C     1 
ATOM   6102  O  O     . GLY B 1 360 ? 370.238 366.751 229.161 1.00 148.44 ? 360 GLY E O     1 
ATOM   6103  N  N     . LEU B 1 361 ? 372.131 367.537 230.093 1.00 132.53 ? 361 LEU E N     1 
ATOM   6104  C  CA    . LEU B 1 361 ? 371.876 368.894 229.628 1.00 131.81 ? 361 LEU E CA    1 
ATOM   6105  C  C     . LEU B 1 361 ? 372.008 368.956 228.113 1.00 131.81 ? 361 LEU E C     1 
ATOM   6106  O  O     . LEU B 1 361 ? 372.761 368.196 227.501 1.00 135.12 ? 361 LEU E O     1 
ATOM   6107  C  CB    . LEU B 1 361 ? 372.844 369.898 230.263 1.00 131.91 ? 361 LEU E CB    1 
ATOM   6108  C  CG    . LEU B 1 361 ? 372.300 370.733 231.424 1.00 135.04 ? 361 LEU E CG    1 
ATOM   6109  C  CD1   . LEU B 1 361 ? 373.443 371.306 232.247 1.00 133.33 ? 361 LEU E CD1   1 
ATOM   6110  C  CD2   . LEU B 1 361 ? 371.398 371.850 230.907 1.00 130.22 ? 361 LEU E CD2   1 
ATOM   6111  N  N     . LYS B 1 362 ? 371.259 369.875 227.506 1.00 120.94 ? 362 LYS E N     1 
ATOM   6112  C  CA    . LYS B 1 362 ? 371.326 370.026 226.057 1.00 119.69 ? 362 LYS E CA    1 
ATOM   6113  C  C     . LYS B 1 362 ? 372.608 370.730 225.637 1.00 125.25 ? 362 LYS E C     1 
ATOM   6114  O  O     . LYS B 1 362 ? 373.145 370.450 224.559 1.00 126.66 ? 362 LYS E O     1 
ATOM   6115  C  CB    . LYS B 1 362 ? 370.108 370.793 225.537 1.00 119.26 ? 362 LYS E CB    1 
ATOM   6116  C  CG    . LYS B 1 362 ? 368.746 370.101 225.737 1.00 122.29 ? 362 LYS E CG    1 
ATOM   6117  C  CD    . LYS B 1 362 ? 368.513 368.820 224.912 1.00 125.94 ? 362 LYS E CD    1 
ATOM   6118  C  CE    . LYS B 1 362 ? 367.111 368.231 225.078 1.00 131.43 ? 362 LYS E CE    1 
ATOM   6119  N  NZ    . LYS B 1 362 ? 366.922 367.627 226.426 1.00 129.83 ? 362 LYS E NZ    1 
ATOM   6120  N  N     . MET B 1 363 ? 373.110 371.645 226.468 1.00 123.62 ? 363 MET E N     1 
ATOM   6121  C  CA    . MET B 1 363 ? 374.211 372.509 226.073 1.00 119.41 ? 363 MET E CA    1 
ATOM   6122  C  C     . MET B 1 363 ? 375.014 372.918 227.297 1.00 121.46 ? 363 MET E C     1 
ATOM   6123  O  O     . MET B 1 363 ? 374.462 373.100 228.385 1.00 128.10 ? 363 MET E O     1 
ATOM   6124  C  CB    . MET B 1 363 ? 373.666 373.736 225.335 1.00 121.32 ? 363 MET E CB    1 
ATOM   6125  C  CG    . MET B 1 363 ? 373.943 373.639 223.872 1.00 123.24 ? 363 MET E CG    1 
ATOM   6126  S  SD    . MET B 1 363 ? 373.275 374.869 222.728 1.00 137.23 ? 363 MET E SD    1 
ATOM   6127  C  CE    . MET B 1 363 ? 373.269 376.364 223.697 1.00 125.94 ? 363 MET E CE    1 
ATOM   6128  N  N     . ALA B 1 364 ? 376.324 373.070 227.107 1.00 104.34 ? 364 ALA E N     1 
ATOM   6129  C  CA    . ALA B 1 364 ? 377.200 373.468 228.199 1.00 101.88 ? 364 ALA E CA    1 
ATOM   6130  C  C     . ALA B 1 364 ? 378.470 374.070 227.622 1.00 106.24 ? 364 ALA E C     1 
ATOM   6131  O  O     . ALA B 1 364 ? 378.804 373.858 226.455 1.00 114.40 ? 364 ALA E O     1 
ATOM   6132  C  CB    . ALA B 1 364 ? 377.532 372.282 229.108 1.00 101.08 ? 364 ALA E CB    1 
ATOM   6133  N  N     . VAL B 1 365 ? 379.177 374.824 228.458 1.00 112.95 ? 365 VAL E N     1 
ATOM   6134  C  CA    . VAL B 1 365 ? 380.452 375.423 228.082 1.00 112.45 ? 365 VAL E CA    1 
ATOM   6135  C  C     . VAL B 1 365 ? 381.330 375.533 229.319 1.00 113.70 ? 365 VAL E C     1 
ATOM   6136  O  O     . VAL B 1 365 ? 380.851 375.872 230.408 1.00 118.92 ? 365 VAL E O     1 
ATOM   6137  C  CB    . VAL B 1 365 ? 380.257 376.797 227.400 1.00 114.89 ? 365 VAL E CB    1 
ATOM   6138  C  CG1   . VAL B 1 365 ? 379.404 377.737 228.250 1.00 115.68 ? 365 VAL E CG1   1 
ATOM   6139  C  CG2   . VAL B 1 365 ? 381.602 377.438 227.089 1.00 113.21 ? 365 VAL E CG2   1 
ATOM   6140  N  N     . THR B 1 366 ? 382.616 375.235 229.141 1.00 102.60 ? 366 THR E N     1 
ATOM   6141  C  CA    . THR B 1 366 ? 383.641 375.374 230.165 1.00 102.52 ? 366 THR E CA    1 
ATOM   6142  C  C     . THR B 1 366 ? 384.606 376.454 229.701 1.00 98.26  ? 366 THR E C     1 
ATOM   6143  O  O     . THR B 1 366 ? 385.089 376.421 228.563 1.00 103.40 ? 366 THR E O     1 
ATOM   6144  C  CB    . THR B 1 366 ? 384.359 374.041 230.404 1.00 104.74 ? 366 THR E CB    1 
ATOM   6145  O  OG1   . THR B 1 366 ? 383.515 373.199 231.200 1.00 108.53 ? 366 THR E OG1   1 
ATOM   6146  C  CG2   . THR B 1 366 ? 385.716 374.231 231.108 1.00 101.72 ? 366 THR E CG2   1 
ATOM   6147  N  N     . PHE B 1 367 ? 384.869 377.406 230.583 1.00 94.24  ? 367 PHE E N     1 
ATOM   6148  C  CA    . PHE B 1 367 ? 385.674 378.583 230.317 1.00 95.45  ? 367 PHE E CA    1 
ATOM   6149  C  C     . PHE B 1 367 ? 386.998 378.493 231.055 1.00 101.18 ? 367 PHE E C     1 
ATOM   6150  O  O     . PHE B 1 367 ? 387.028 378.168 232.241 1.00 108.80 ? 367 PHE E O     1 
ATOM   6151  C  CB    . PHE B 1 367 ? 384.883 379.816 230.758 1.00 102.95 ? 367 PHE E CB    1 
ATOM   6152  C  CG    . PHE B 1 367 ? 385.497 381.117 230.374 1.00 104.12 ? 367 PHE E CG    1 
ATOM   6153  C  CD1   . PHE B 1 367 ? 386.356 381.778 231.240 1.00 101.14 ? 367 PHE E CD1   1 
ATOM   6154  C  CD2   . PHE B 1 367 ? 385.229 381.677 229.148 1.00 106.48 ? 367 PHE E CD2   1 
ATOM   6155  C  CE1   . PHE B 1 367 ? 386.917 382.982 230.886 1.00 102.89 ? 367 PHE E CE1   1 
ATOM   6156  C  CE2   . PHE B 1 367 ? 385.785 382.867 228.791 1.00 108.25 ? 367 PHE E CE2   1 
ATOM   6157  C  CZ    . PHE B 1 367 ? 386.635 383.527 229.658 1.00 108.04 ? 367 PHE E CZ    1 
ATOM   6158  N  N     . ILE B 1 368 ? 388.088 378.783 230.343 1.00 97.93  ? 368 ILE E N     1 
ATOM   6159  C  CA    . ILE B 1 368 ? 389.401 379.054 230.924 1.00 91.87  ? 368 ILE E CA    1 
ATOM   6160  C  C     . ILE B 1 368 ? 389.802 380.449 230.480 1.00 94.53  ? 368 ILE E C     1 
ATOM   6161  O  O     . ILE B 1 368 ? 389.541 380.826 229.335 1.00 105.27 ? 368 ILE E O     1 
ATOM   6162  C  CB    . ILE B 1 368 ? 390.485 378.041 230.482 1.00 91.54  ? 368 ILE E CB    1 
ATOM   6163  C  CG1   . ILE B 1 368 ? 389.971 376.607 230.226 1.00 97.18  ? 368 ILE E CG1   1 
ATOM   6164  C  CG2   . ILE B 1 368 ? 391.601 378.005 231.508 1.00 94.65  ? 368 ILE E CG2   1 
ATOM   6165  C  CD1   . ILE B 1 368 ? 389.163 375.972 231.342 1.00 100.19 ? 368 ILE E CD1   1 
ATOM   6166  N  N     . GLY B 1 369 ? 390.410 381.221 231.383 1.00 95.28  ? 369 GLY E N     1 
ATOM   6167  C  CA    . GLY B 1 369 ? 390.941 382.524 231.008 1.00 101.93 ? 369 GLY E CA    1 
ATOM   6168  C  C     . GLY B 1 369 ? 392.257 382.843 231.682 1.00 104.34 ? 369 GLY E C     1 
ATOM   6169  O  O     . GLY B 1 369 ? 392.368 382.707 232.901 1.00 107.33 ? 369 GLY E O     1 
ATOM   6170  N  N     . ASN B 1 370 ? 393.259 383.260 230.913 1.00 103.39 ? 370 ASN E N     1 
ATOM   6171  C  CA    . ASN B 1 370 ? 394.560 383.658 231.451 1.00 99.74  ? 370 ASN E CA    1 
ATOM   6172  C  C     . ASN B 1 370 ? 394.616 385.161 231.690 1.00 101.95 ? 370 ASN E C     1 
ATOM   6173  O  O     . ASN B 1 370 ? 395.547 385.839 231.269 1.00 106.51 ? 370 ASN E O     1 
ATOM   6174  C  CB    . ASN B 1 370 ? 395.660 383.212 230.499 1.00 101.58 ? 370 ASN E CB    1 
ATOM   6175  C  CG    . ASN B 1 370 ? 397.030 383.218 231.140 1.00 105.15 ? 370 ASN E CG    1 
ATOM   6176  O  OD1   . ASN B 1 370 ? 397.203 383.687 232.264 1.00 109.97 ? 370 ASN E OD1   1 
ATOM   6177  N  ND2   . ASN B 1 370 ? 398.018 382.706 230.420 1.00 109.29 ? 370 ASN E ND2   1 
ATOM   6178  N  N     . SER B 1 371 ? 393.623 385.704 232.388 1.00 106.76 ? 371 SER E N     1 
ATOM   6179  C  CA    . SER B 1 371 ? 393.569 387.144 232.587 1.00 106.60 ? 371 SER E CA    1 
ATOM   6180  C  C     . SER B 1 371 ? 394.664 387.597 233.548 1.00 103.71 ? 371 SER E C     1 
ATOM   6181  O  O     . SER B 1 371 ? 395.128 386.844 234.407 1.00 103.40 ? 371 SER E O     1 
ATOM   6182  C  CB    . SER B 1 371 ? 392.205 387.565 233.126 1.00 110.36 ? 371 SER E CB    1 
ATOM   6183  O  OG    . SER B 1 371 ? 392.209 387.591 234.541 1.00 116.09 ? 371 SER E OG    1 
ATOM   6184  N  N     . THR B 1 372 ? 395.073 388.854 233.391 1.00 105.86 ? 372 THR E N     1 
ATOM   6185  C  CA    . THR B 1 372 ? 396.083 389.452 234.254 1.00 101.22 ? 372 THR E CA    1 
ATOM   6186  C  C     . THR B 1 372 ? 395.525 389.937 235.587 1.00 103.44 ? 372 THR E C     1 
ATOM   6187  O  O     . THR B 1 372 ? 396.291 390.464 236.399 1.00 106.08 ? 372 THR E O     1 
ATOM   6188  C  CB    . THR B 1 372 ? 396.767 390.621 233.540 1.00 102.22 ? 372 THR E CB    1 
ATOM   6189  O  OG1   . THR B 1 372 ? 395.806 391.642 233.256 1.00 111.15 ? 372 THR E OG1   1 
ATOM   6190  C  CG2   . THR B 1 372 ? 397.412 390.160 232.243 1.00 103.49 ? 372 THR E CG2   1 
ATOM   6191  N  N     . ALA B 1 373 ? 394.221 389.781 235.839 1.00 110.38 ? 373 ALA E N     1 
ATOM   6192  C  CA    . ALA B 1 373 ? 393.654 390.129 237.137 1.00 111.19 ? 373 ALA E CA    1 
ATOM   6193  C  C     . ALA B 1 373 ? 394.132 389.218 238.262 1.00 111.91 ? 373 ALA E C     1 
ATOM   6194  O  O     . ALA B 1 373 ? 393.964 389.574 239.432 1.00 112.38 ? 373 ALA E O     1 
ATOM   6195  C  CB    . ALA B 1 373 ? 392.128 390.092 237.063 1.00 112.21 ? 373 ALA E CB    1 
ATOM   6196  N  N     . ILE B 1 374 ? 394.725 388.063 237.943 1.00 107.11 ? 374 ILE E N     1 
ATOM   6197  C  CA    . ILE B 1 374 ? 395.318 387.198 238.958 1.00 107.84 ? 374 ILE E CA    1 
ATOM   6198  C  C     . ILE B 1 374 ? 396.510 387.859 239.651 1.00 110.99 ? 374 ILE E C     1 
ATOM   6199  O  O     . ILE B 1 374 ? 396.913 387.420 240.740 1.00 113.40 ? 374 ILE E O     1 
ATOM   6200  C  CB    . ILE B 1 374 ? 395.705 385.857 238.299 1.00 106.63 ? 374 ILE E CB    1 
ATOM   6201  C  CG1   . ILE B 1 374 ? 395.816 384.737 239.339 1.00 110.51 ? 374 ILE E CG1   1 
ATOM   6202  C  CG2   . ILE B 1 374 ? 396.985 385.995 237.482 1.00 112.76 ? 374 ILE E CG2   1 
ATOM   6203  C  CD1   . ILE B 1 374 ? 394.487 384.114 239.700 1.00 106.90 ? 374 ILE E CD1   1 
ATOM   6204  N  N     . GLN B 1 375 ? 397.101 388.894 239.041 1.00 107.87 ? 375 GLN E N     1 
ATOM   6205  C  CA    . GLN B 1 375 ? 398.127 389.670 239.725 1.00 103.23 ? 375 GLN E CA    1 
ATOM   6206  C  C     . GLN B 1 375 ? 397.592 390.291 241.007 1.00 109.78 ? 375 GLN E C     1 
ATOM   6207  O  O     . GLN B 1 375 ? 398.345 390.451 241.968 1.00 114.12 ? 375 GLN E O     1 
ATOM   6208  C  CB    . GLN B 1 375 ? 398.686 390.753 238.796 1.00 105.08 ? 375 GLN E CB    1 
ATOM   6209  C  CG    . GLN B 1 375 ? 397.874 392.046 238.727 1.00 108.06 ? 375 GLN E CG    1 
ATOM   6210  C  CD    . GLN B 1 375 ? 398.212 392.884 237.513 1.00 115.85 ? 375 GLN E CD    1 
ATOM   6211  O  OE1   . GLN B 1 375 ? 399.233 392.671 236.861 1.00 119.83 ? 375 GLN E OE1   1 
ATOM   6212  N  NE2   . GLN B 1 375 ? 397.352 393.847 237.203 1.00 117.36 ? 375 GLN E NE2   1 
ATOM   6213  N  N     . GLU B 1 376 ? 396.302 390.636 241.049 1.00 124.57 ? 376 GLU E N     1 
ATOM   6214  C  CA    . GLU B 1 376 ? 395.719 391.148 242.286 1.00 125.57 ? 376 GLU E CA    1 
ATOM   6215  C  C     . GLU B 1 376 ? 395.729 390.084 243.377 1.00 121.63 ? 376 GLU E C     1 
ATOM   6216  O  O     . GLU B 1 376 ? 396.041 390.378 244.536 1.00 125.69 ? 376 GLU E O     1 
ATOM   6217  C  CB    . GLU B 1 376 ? 394.291 391.644 242.039 1.00 120.62 ? 376 GLU E CB    1 
ATOM   6218  C  CG    . GLU B 1 376 ? 394.112 392.584 240.841 1.00 125.50 ? 376 GLU E CG    1 
ATOM   6219  C  CD    . GLU B 1 376 ? 395.124 393.714 240.809 1.00 128.46 ? 376 GLU E CD    1 
ATOM   6220  O  OE1   . GLU B 1 376 ? 395.465 394.240 241.889 1.00 127.32 ? 376 GLU E OE1   1 
ATOM   6221  O  OE2   . GLU B 1 376 ? 395.580 394.075 239.703 1.00 124.45 ? 376 GLU E OE2   1 
ATOM   6222  N  N     . LEU B 1 377 ? 395.401 388.841 243.021 1.00 105.29 ? 377 LEU E N     1 
ATOM   6223  C  CA    . LEU B 1 377 ? 395.427 387.753 243.992 1.00 108.09 ? 377 LEU E CA    1 
ATOM   6224  C  C     . LEU B 1 377 ? 396.842 387.499 244.498 1.00 112.30 ? 377 LEU E C     1 
ATOM   6225  O  O     . LEU B 1 377 ? 397.065 387.321 245.703 1.00 108.35 ? 377 LEU E O     1 
ATOM   6226  C  CB    . LEU B 1 377 ? 394.852 386.489 243.357 1.00 104.44 ? 377 LEU E CB    1 
ATOM   6227  C  CG    . LEU B 1 377 ? 394.835 385.242 244.241 1.00 104.72 ? 377 LEU E CG    1 
ATOM   6228  C  CD1   . LEU B 1 377 ? 393.492 384.562 244.162 1.00 109.55 ? 377 LEU E CD1   1 
ATOM   6229  C  CD2   . LEU B 1 377 ? 395.940 384.274 243.844 1.00 99.24  ? 377 LEU E CD2   1 
ATOM   6230  N  N     . PHE B 1 378 ? 397.811 387.463 243.582 1.00 109.91 ? 378 PHE E N     1 
ATOM   6231  C  CA    . PHE B 1 378 ? 399.194 387.249 243.998 1.00 102.01 ? 378 PHE E CA    1 
ATOM   6232  C  C     . PHE B 1 378 ? 399.706 388.418 244.831 1.00 104.90 ? 378 PHE E C     1 
ATOM   6233  O  O     . PHE B 1 378 ? 400.466 388.218 245.785 1.00 106.97 ? 378 PHE E O     1 
ATOM   6234  C  CB    . PHE B 1 378 ? 400.085 387.016 242.775 1.00 103.24 ? 378 PHE E CB    1 
ATOM   6235  C  CG    . PHE B 1 378 ? 399.834 385.704 242.069 1.00 104.30 ? 378 PHE E CG    1 
ATOM   6236  C  CD1   . PHE B 1 378 ? 400.004 384.493 242.726 1.00 104.85 ? 378 PHE E CD1   1 
ATOM   6237  C  CD2   . PHE B 1 378 ? 399.435 385.683 240.746 1.00 105.56 ? 378 PHE E CD2   1 
ATOM   6238  C  CE1   . PHE B 1 378 ? 399.775 383.297 242.078 1.00 104.56 ? 378 PHE E CE1   1 
ATOM   6239  C  CE2   . PHE B 1 378 ? 399.205 384.487 240.096 1.00 104.72 ? 378 PHE E CE2   1 
ATOM   6240  C  CZ    . PHE B 1 378 ? 399.376 383.295 240.762 1.00 104.43 ? 378 PHE E CZ    1 
ATOM   6241  N  N     . LYS B 1 379 ? 399.282 389.640 244.502 1.00 113.01 ? 379 LYS E N     1 
ATOM   6242  C  CA    . LYS B 1 379 ? 399.632 390.805 245.304 1.00 113.63 ? 379 LYS E CA    1 
ATOM   6243  C  C     . LYS B 1 379 ? 399.068 390.682 246.711 1.00 116.54 ? 379 LYS E C     1 
ATOM   6244  O  O     . LYS B 1 379 ? 399.754 390.988 247.690 1.00 122.78 ? 379 LYS E O     1 
ATOM   6245  C  CB    . LYS B 1 379 ? 399.102 392.067 244.620 1.00 114.03 ? 379 LYS E CB    1 
ATOM   6246  C  CG    . LYS B 1 379 ? 399.453 393.396 245.309 1.00 116.68 ? 379 LYS E CG    1 
ATOM   6247  C  CD    . LYS B 1 379 ? 398.941 394.637 244.560 1.00 114.87 ? 379 LYS E CD    1 
ATOM   6248  C  CE    . LYS B 1 379 ? 399.267 395.966 245.254 1.00 115.48 ? 379 LYS E CE    1 
ATOM   6249  N  NZ    . LYS B 1 379 ? 398.762 397.154 244.511 1.00 119.18 ? 379 LYS E NZ    1 
ATOM   6250  N  N     . ARG B 1 380 ? 397.817 390.235 246.825 1.00 111.59 ? 380 ARG E N     1 
ATOM   6251  C  CA    . ARG B 1 380 ? 397.185 390.054 248.129 1.00 112.06 ? 380 ARG E CA    1 
ATOM   6252  C  C     . ARG B 1 380 ? 397.936 389.021 248.962 1.00 113.46 ? 380 ARG E C     1 
ATOM   6253  O  O     . ARG B 1 380 ? 398.225 389.245 250.148 1.00 114.14 ? 380 ARG E O     1 
ATOM   6254  C  CB    . ARG B 1 380 ? 395.731 389.631 247.908 1.00 114.67 ? 380 ARG E CB    1 
ATOM   6255  C  CG    . ARG B 1 380 ? 394.859 389.376 249.147 1.00 111.81 ? 380 ARG E CG    1 
ATOM   6256  C  CD    . ARG B 1 380 ? 394.022 388.124 248.939 1.00 112.97 ? 380 ARG E CD    1 
ATOM   6257  N  NE    . ARG B 1 380 ? 393.194 388.240 247.741 1.00 116.90 ? 380 ARG E NE    1 
ATOM   6258  C  CZ    . ARG B 1 380 ? 392.782 387.237 246.972 1.00 120.15 ? 380 ARG E CZ    1 
ATOM   6259  N  NH1   . ARG B 1 380 ? 393.070 385.972 247.247 1.00 117.43 ? 380 ARG E NH1   1 
ATOM   6260  N  NH2   . ARG B 1 380 ? 392.058 387.510 245.890 1.00 117.12 ? 380 ARG E NH2   1 
ATOM   6261  N  N     . ILE B 1 381 ? 398.256 387.876 248.354 1.00 111.49 ? 381 ILE E N     1 
ATOM   6262  C  CA    . ILE B 1 381 ? 398.932 386.814 249.092 1.00 110.73 ? 381 ILE E CA    1 
ATOM   6263  C  C     . ILE B 1 381 ? 400.327 387.263 249.508 1.00 112.38 ? 381 ILE E C     1 
ATOM   6264  O  O     . ILE B 1 381 ? 400.760 387.010 250.637 1.00 113.32 ? 381 ILE E O     1 
ATOM   6265  C  CB    . ILE B 1 381 ? 398.970 385.512 248.266 1.00 107.62 ? 381 ILE E CB    1 
ATOM   6266  C  CG1   . ILE B 1 381 ? 397.563 384.920 248.119 1.00 109.33 ? 381 ILE E CG1   1 
ATOM   6267  C  CG2   . ILE B 1 381 ? 399.886 384.475 248.924 1.00 106.05 ? 381 ILE E CG2   1 
ATOM   6268  C  CD1   . ILE B 1 381 ? 397.398 384.005 246.920 1.00 114.10 ? 381 ILE E CD1   1 
ATOM   6269  N  N     . SER B 1 382 ? 401.046 387.950 248.616 1.00 119.05 ? 382 SER E N     1 
ATOM   6270  C  CA    . SER B 1 382 ? 402.373 388.441 248.968 1.00 114.87 ? 382 SER E CA    1 
ATOM   6271  C  C     . SER B 1 382 ? 402.309 389.518 250.043 1.00 114.43 ? 382 SER E C     1 
ATOM   6272  O  O     . SER B 1 382 ? 403.202 389.590 250.892 1.00 120.08 ? 382 SER E O     1 
ATOM   6273  C  CB    . SER B 1 382 ? 403.079 388.977 247.725 1.00 117.57 ? 382 SER E CB    1 
ATOM   6274  O  OG    . SER B 1 382 ? 402.233 389.852 247.003 1.00 124.55 ? 382 SER E OG    1 
ATOM   6275  N  N     . GLU B 1 383 ? 401.274 390.360 250.028 1.00 114.06 ? 383 GLU E N     1 
ATOM   6276  C  CA    . GLU B 1 383 ? 401.136 391.376 251.065 1.00 116.04 ? 383 GLU E CA    1 
ATOM   6277  C  C     . GLU B 1 383 ? 400.898 390.739 252.426 1.00 116.00 ? 383 GLU E C     1 
ATOM   6278  O  O     . GLU B 1 383 ? 401.512 391.144 253.420 1.00 120.53 ? 383 GLU E O     1 
ATOM   6279  C  CB    . GLU B 1 383 ? 399.997 392.335 250.714 1.00 116.00 ? 383 GLU E CB    1 
ATOM   6280  C  CG    . GLU B 1 383 ? 400.150 393.746 251.279 1.00 118.44 ? 383 GLU E CG    1 
ATOM   6281  C  CD    . GLU B 1 383 ? 399.825 393.839 252.759 1.00 122.30 ? 383 GLU E CD    1 
ATOM   6282  O  OE1   . GLU B 1 383 ? 398.845 393.204 253.203 1.00 122.70 ? 383 GLU E OE1   1 
ATOM   6283  O  OE2   . GLU B 1 383 ? 400.554 394.550 253.481 1.00 120.69 ? 383 GLU E OE2   1 
ATOM   6284  N  N     . GLN B 1 384 ? 400.017 389.737 252.492 1.00 99.85  ? 384 GLN E N     1 
ATOM   6285  C  CA    . GLN B 1 384 ? 399.795 389.047 253.761 1.00 96.52  ? 384 GLN E CA    1 
ATOM   6286  C  C     . GLN B 1 384 ? 401.051 388.307 254.209 1.00 100.80 ? 384 GLN E C     1 
ATOM   6287  O  O     . GLN B 1 384 ? 401.382 388.287 255.406 1.00 106.40 ? 384 GLN E O     1 
ATOM   6288  C  CB    . GLN B 1 384 ? 398.611 388.089 253.635 1.00 96.77  ? 384 GLN E CB    1 
ATOM   6289  C  CG    . GLN B 1 384 ? 397.284 388.798 253.404 1.00 101.71 ? 384 GLN E CG    1 
ATOM   6290  C  CD    . GLN B 1 384 ? 396.114 387.843 253.281 1.00 106.09 ? 384 GLN E CD    1 
ATOM   6291  O  OE1   . GLN B 1 384 ? 396.285 386.626 253.299 1.00 102.50 ? 384 GLN E OE1   1 
ATOM   6292  N  NE2   . GLN B 1 384 ? 394.914 388.394 253.153 1.00 109.26 ? 384 GLN E NE2   1 
ATOM   6293  N  N     . PHE B 1 385 ? 401.770 387.707 253.255 1.00 105.14 ? 385 PHE E N     1 
ATOM   6294  C  CA    . PHE B 1 385 ? 403.022 387.026 253.561 1.00 105.59 ? 385 PHE E CA    1 
ATOM   6295  C  C     . PHE B 1 385 ? 404.035 387.989 254.159 1.00 104.89 ? 385 PHE E C     1 
ATOM   6296  O  O     . PHE B 1 385 ? 404.684 387.675 255.158 1.00 109.10 ? 385 PHE E O     1 
ATOM   6297  C  CB    . PHE B 1 385 ? 403.578 386.379 252.290 1.00 103.16 ? 385 PHE E CB    1 
ATOM   6298  C  CG    . PHE B 1 385 ? 404.825 385.562 252.509 1.00 96.55  ? 385 PHE E CG    1 
ATOM   6299  C  CD1   . PHE B 1 385 ? 404.737 384.218 252.812 1.00 101.95 ? 385 PHE E CD1   1 
ATOM   6300  C  CD2   . PHE B 1 385 ? 406.083 386.130 252.378 1.00 94.02  ? 385 PHE E CD2   1 
ATOM   6301  C  CE1   . PHE B 1 385 ? 405.873 383.464 253.005 1.00 104.71 ? 385 PHE E CE1   1 
ATOM   6302  C  CE2   . PHE B 1 385 ? 407.218 385.380 252.575 1.00 97.92  ? 385 PHE E CE2   1 
ATOM   6303  C  CZ    . PHE B 1 385 ? 407.114 384.046 252.883 1.00 104.84 ? 385 PHE E CZ    1 
ATOM   6304  N  N     . THR B 1 386 ? 404.193 389.164 253.550 1.00 109.45 ? 386 THR E N     1 
ATOM   6305  C  CA    . THR B 1 386 ? 405.141 390.141 254.071 1.00 105.84 ? 386 THR E CA    1 
ATOM   6306  C  C     . THR B 1 386 ? 404.699 390.676 255.424 1.00 105.74 ? 386 THR E C     1 
ATOM   6307  O  O     . THR B 1 386 ? 405.543 390.914 256.295 1.00 109.01 ? 386 THR E O     1 
ATOM   6308  C  CB    . THR B 1 386 ? 405.312 391.293 253.084 1.00 109.84 ? 386 THR E CB    1 
ATOM   6309  O  OG1   . THR B 1 386 ? 404.032 391.677 252.571 1.00 114.44 ? 386 THR E OG1   1 
ATOM   6310  C  CG2   . THR B 1 386 ? 406.217 390.879 251.934 1.00 111.57 ? 386 THR E CG2   1 
ATOM   6311  N  N     . ALA B 1 387 ? 403.389 390.853 255.621 1.00 100.86 ? 387 ALA E N     1 
ATOM   6312  C  CA    . ALA B 1 387 ? 402.888 391.337 256.902 1.00 102.37 ? 387 ALA E CA    1 
ATOM   6313  C  C     . ALA B 1 387 ? 403.215 390.365 258.026 1.00 103.67 ? 387 ALA E C     1 
ATOM   6314  O  O     . ALA B 1 387 ? 403.618 390.784 259.117 1.00 103.31 ? 387 ALA E O     1 
ATOM   6315  C  CB    . ALA B 1 387 ? 401.381 391.571 256.820 1.00 98.58  ? 387 ALA E CB    1 
ATOM   6316  N  N     . MET B 1 388 ? 403.056 389.061 257.781 1.00 99.89  ? 388 MET E N     1 
ATOM   6317  C  CA    . MET B 1 388 ? 403.420 388.089 258.812 1.00 93.95  ? 388 MET E CA    1 
ATOM   6318  C  C     . MET B 1 388 ? 404.934 387.943 258.937 1.00 98.01  ? 388 MET E C     1 
ATOM   6319  O  O     . MET B 1 388 ? 405.462 387.841 260.050 1.00 104.40 ? 388 MET E O     1 
ATOM   6320  C  CB    . MET B 1 388 ? 402.788 386.731 258.519 1.00 92.16  ? 388 MET E CB    1 
ATOM   6321  C  CG    . MET B 1 388 ? 401.355 386.587 258.990 1.00 99.76  ? 388 MET E CG    1 
ATOM   6322  S  SD    . MET B 1 388 ? 400.886 384.859 259.104 1.00 109.19 ? 388 MET E SD    1 
ATOM   6323  C  CE    . MET B 1 388 ? 399.704 384.771 257.778 1.00 98.33  ? 388 MET E CE    1 
ATOM   6324  N  N     . PHE B 1 389 ? 405.647 387.931 257.810 1.00 99.03  ? 389 PHE E N     1 
ATOM   6325  C  CA    . PHE B 1 389 ? 407.083 387.686 257.810 1.00 96.30  ? 389 PHE E CA    1 
ATOM   6326  C  C     . PHE B 1 389 ? 407.876 388.844 258.399 1.00 99.84  ? 389 PHE E C     1 
ATOM   6327  O  O     . PHE B 1 389 ? 409.022 388.641 258.814 1.00 102.56 ? 389 PHE E O     1 
ATOM   6328  C  CB    . PHE B 1 389 ? 407.541 387.409 256.376 1.00 96.44  ? 389 PHE E CB    1 
ATOM   6329  C  CG    . PHE B 1 389 ? 408.971 386.977 256.262 1.00 94.69  ? 389 PHE E CG    1 
ATOM   6330  C  CD1   . PHE B 1 389 ? 409.335 385.668 256.512 1.00 93.54  ? 389 PHE E CD1   1 
ATOM   6331  C  CD2   . PHE B 1 389 ? 409.951 387.880 255.894 1.00 101.74 ? 389 PHE E CD2   1 
ATOM   6332  C  CE1   . PHE B 1 389 ? 410.650 385.270 256.400 1.00 96.86  ? 389 PHE E CE1   1 
ATOM   6333  C  CE2   . PHE B 1 389 ? 411.266 387.487 255.783 1.00 102.53 ? 389 PHE E CE2   1 
ATOM   6334  C  CZ    . PHE B 1 389 ? 411.615 386.181 256.037 1.00 99.91  ? 389 PHE E CZ    1 
ATOM   6335  N  N     . ARG B 1 390 ? 407.300 390.049 258.437 1.00 106.06 ? 390 ARG E N     1 
ATOM   6336  C  CA    . ARG B 1 390 ? 407.974 391.174 259.076 1.00 105.85 ? 390 ARG E CA    1 
ATOM   6337  C  C     . ARG B 1 390 ? 408.214 390.896 260.553 1.00 108.23 ? 390 ARG E C     1 
ATOM   6338  O  O     . ARG B 1 390 ? 409.287 391.203 261.085 1.00 106.25 ? 390 ARG E O     1 
ATOM   6339  C  CB    . ARG B 1 390 ? 407.136 392.438 258.892 1.00 105.76 ? 390 ARG E CB    1 
ATOM   6340  C  CG    . ARG B 1 390 ? 407.806 393.730 259.331 1.00 111.37 ? 390 ARG E CG    1 
ATOM   6341  C  CD    . ARG B 1 390 ? 406.888 394.917 259.094 1.00 109.32 ? 390 ARG E CD    1 
ATOM   6342  N  NE    . ARG B 1 390 ? 406.715 395.186 257.668 1.00 110.18 ? 390 ARG E NE    1 
ATOM   6343  C  CZ    . ARG B 1 390 ? 405.657 395.761 257.105 1.00 111.45 ? 390 ARG E CZ    1 
ATOM   6344  N  NH1   . ARG B 1 390 ? 404.627 396.196 257.819 1.00 113.47 ? 390 ARG E NH1   1 
ATOM   6345  N  NH2   . ARG B 1 390 ? 405.630 395.908 255.784 1.00 108.53 ? 390 ARG E NH2   1 
ATOM   6346  N  N     . ARG B 1 391 ? 407.228 390.309 261.226 1.00 95.98  ? 391 ARG E N     1 
ATOM   6347  C  CA    . ARG B 1 391 ? 407.336 389.910 262.622 1.00 96.55  ? 391 ARG E CA    1 
ATOM   6348  C  C     . ARG B 1 391 ? 407.830 388.480 262.811 1.00 97.86  ? 391 ARG E C     1 
ATOM   6349  O  O     . ARG B 1 391 ? 408.040 388.080 263.961 1.00 95.01  ? 391 ARG E O     1 
ATOM   6350  C  CB    . ARG B 1 391 ? 405.976 390.052 263.314 1.00 96.07  ? 391 ARG E CB    1 
ATOM   6351  C  CG    . ARG B 1 391 ? 405.364 391.446 263.271 1.00 92.35  ? 391 ARG E CG    1 
ATOM   6352  C  CD    . ARG B 1 391 ? 406.192 392.457 264.039 1.00 89.64  ? 391 ARG E CD    1 
ATOM   6353  N  NE    . ARG B 1 391 ? 405.394 393.618 264.427 1.00 94.58  ? 391 ARG E NE    1 
ATOM   6354  C  CZ    . ARG B 1 391 ? 404.883 393.856 265.632 1.00 100.89 ? 391 ARG E CZ    1 
ATOM   6355  N  NH1   . ARG B 1 391 ? 405.009 393.000 266.637 1.00 98.38  ? 391 ARG E NH1   1 
ATOM   6356  N  NH2   . ARG B 1 391 ? 404.209 394.984 265.835 1.00 102.34 ? 391 ARG E NH2   1 
ATOM   6357  N  N     . LYS B 1 392 ? 408.061 387.735 261.724 1.00 101.06 ? 392 LYS E N     1 
ATOM   6358  C  CA    . LYS B 1 392 ? 408.242 386.275 261.709 1.00 100.82 ? 392 LYS E CA    1 
ATOM   6359  C  C     . LYS B 1 392 ? 407.265 385.596 262.670 1.00 99.86  ? 392 LYS E C     1 
ATOM   6360  O  O     . LYS B 1 392 ? 407.640 384.977 263.666 1.00 101.34 ? 392 LYS E O     1 
ATOM   6361  C  CB    . LYS B 1 392 ? 409.696 385.859 261.981 1.00 101.08 ? 392 LYS E CB    1 
ATOM   6362  C  CG    . LYS B 1 392 ? 410.491 386.635 263.032 1.00 102.02 ? 392 LYS E CG    1 
ATOM   6363  C  CD    . LYS B 1 392 ? 411.903 386.071 263.262 1.00 105.30 ? 392 LYS E CD    1 
ATOM   6364  C  CE    . LYS B 1 392 ? 412.785 386.061 262.012 1.00 106.79 ? 392 LYS E CE    1 
ATOM   6365  N  NZ    . LYS B 1 392 ? 412.841 387.382 261.326 1.00 105.68 ? 392 LYS E NZ    1 
ATOM   6366  N  N     . ALA B 1 393 ? 405.979 385.755 262.342 1.00 104.13 ? 393 ALA E N     1 
ATOM   6367  C  CA    . ALA B 1 393 ? 404.907 385.424 263.275 1.00 110.36 ? 393 ALA E CA    1 
ATOM   6368  C  C     . ALA B 1 393 ? 404.872 383.938 263.605 1.00 111.31 ? 393 ALA E C     1 
ATOM   6369  O  O     . ALA B 1 393 ? 404.705 383.566 264.771 1.00 112.59 ? 393 ALA E O     1 
ATOM   6370  C  CB    . ALA B 1 393 ? 403.566 385.867 262.695 1.00 107.44 ? 393 ALA E CB    1 
ATOM   6371  N  N     . PHE B 1 394 ? 405.027 383.075 262.592 1.00 93.14  ? 394 PHE E N     1 
ATOM   6372  C  CA    . PHE B 1 394 ? 404.884 381.628 262.737 1.00 89.31  ? 394 PHE E CA    1 
ATOM   6373  C  C     . PHE B 1 394 ? 406.101 380.884 262.191 1.00 92.21  ? 394 PHE E C     1 
ATOM   6374  O  O     . PHE B 1 394 ? 406.020 379.679 261.933 1.00 94.52  ? 394 PHE E O     1 
ATOM   6375  C  CB    . PHE B 1 394 ? 403.609 381.149 262.029 1.00 93.30  ? 394 PHE E CB    1 
ATOM   6376  C  CG    . PHE B 1 394 ? 402.330 381.589 262.693 1.00 95.43  ? 394 PHE E CG    1 
ATOM   6377  C  CD1   . PHE B 1 394 ? 401.857 382.882 262.543 1.00 92.15  ? 394 PHE E CD1   1 
ATOM   6378  C  CD2   . PHE B 1 394 ? 401.580 380.694 263.436 1.00 102.41 ? 394 PHE E CD2   1 
ATOM   6379  C  CE1   . PHE B 1 394 ? 400.682 383.280 263.145 1.00 89.21  ? 394 PHE E CE1   1 
ATOM   6380  C  CE2   . PHE B 1 394 ? 400.401 381.089 264.039 1.00 101.58 ? 394 PHE E CE2   1 
ATOM   6381  C  CZ    . PHE B 1 394 ? 399.952 382.382 263.892 1.00 90.82  ? 394 PHE E CZ    1 
ATOM   6382  N  N     . LEU B 1 395 ? 407.240 381.564 262.028 1.00 95.00  ? 395 LEU E N     1 
ATOM   6383  C  CA    . LEU B 1 395 ? 408.348 380.970 261.289 1.00 97.02  ? 395 LEU E CA    1 
ATOM   6384  C  C     . LEU B 1 395 ? 409.049 379.849 262.035 1.00 100.54 ? 395 LEU E C     1 
ATOM   6385  O  O     . LEU B 1 395 ? 409.667 379.000 261.385 1.00 107.90 ? 395 LEU E O     1 
ATOM   6386  C  CB    . LEU B 1 395 ? 409.400 382.023 260.939 1.00 96.79  ? 395 LEU E CB    1 
ATOM   6387  C  CG    . LEU B 1 395 ? 409.174 383.068 259.848 1.00 105.30 ? 395 LEU E CG    1 
ATOM   6388  C  CD1   . LEU B 1 395 ? 410.509 383.708 259.537 1.00 105.61 ? 395 LEU E CD1   1 
ATOM   6389  C  CD2   . LEU B 1 395 ? 408.573 382.493 258.577 1.00 103.40 ? 395 LEU E CD2   1 
ATOM   6390  N  N     . HIS B 1 396 ? 409.003 379.831 263.367 1.00 88.84  ? 396 HIS E N     1 
ATOM   6391  C  CA    . HIS B 1 396 ? 409.776 378.823 264.082 1.00 86.19  ? 396 HIS E CA    1 
ATOM   6392  C  C     . HIS B 1 396 ? 409.194 377.431 263.898 1.00 88.33  ? 396 HIS E C     1 
ATOM   6393  O  O     . HIS B 1 396 ? 409.934 376.446 263.956 1.00 92.79  ? 396 HIS E O     1 
ATOM   6394  C  CB    . HIS B 1 396 ? 409.887 379.183 265.563 1.00 90.80  ? 396 HIS E CB    1 
ATOM   6395  C  CG    . HIS B 1 396 ? 408.677 378.842 266.372 1.00 89.00  ? 396 HIS E CG    1 
ATOM   6396  N  ND1   . HIS B 1 396 ? 407.563 379.652 266.417 1.00 87.07  ? 396 HIS E ND1   1 
ATOM   6397  C  CD2   . HIS B 1 396 ? 408.409 377.786 267.175 1.00 92.72  ? 396 HIS E CD2   1 
ATOM   6398  C  CE1   . HIS B 1 396 ? 406.661 379.110 267.215 1.00 88.05  ? 396 HIS E CE1   1 
ATOM   6399  N  NE2   . HIS B 1 396 ? 407.148 377.977 267.686 1.00 86.67  ? 396 HIS E NE2   1 
ATOM   6400  N  N     . TRP B 1 397 ? 407.890 377.322 263.638 1.00 92.52  ? 397 TRP E N     1 
ATOM   6401  C  CA    . TRP B 1 397 ? 407.325 376.015 263.323 1.00 88.95  ? 397 TRP E CA    1 
ATOM   6402  C  C     . TRP B 1 397 ? 407.879 375.479 262.011 1.00 98.89  ? 397 TRP E C     1 
ATOM   6403  O  O     . TRP B 1 397 ? 408.187 374.287 261.900 1.00 106.57 ? 397 TRP E O     1 
ATOM   6404  C  CB    . TRP B 1 397 ? 405.804 376.092 263.253 1.00 90.36  ? 397 TRP E CB    1 
ATOM   6405  C  CG    . TRP B 1 397 ? 405.147 376.473 264.529 1.00 98.84  ? 397 TRP E CG    1 
ATOM   6406  C  CD1   . TRP B 1 397 ? 404.306 377.528 264.729 1.00 101.90 ? 397 TRP E CD1   1 
ATOM   6407  C  CD2   . TRP B 1 397 ? 405.286 375.824 265.796 1.00 102.13 ? 397 TRP E CD2   1 
ATOM   6408  N  NE1   . TRP B 1 397 ? 403.895 377.560 266.036 1.00 106.12 ? 397 TRP E NE1   1 
ATOM   6409  C  CE2   . TRP B 1 397 ? 404.478 376.520 266.711 1.00 101.33 ? 397 TRP E CE2   1 
ATOM   6410  C  CE3   . TRP B 1 397 ? 405.984 374.697 266.236 1.00 104.57 ? 397 TRP E CE3   1 
ATOM   6411  C  CZ2   . TRP B 1 397 ? 404.371 376.143 268.043 1.00 102.61 ? 397 TRP E CZ2   1 
ATOM   6412  C  CZ3   . TRP B 1 397 ? 405.879 374.328 267.561 1.00 101.31 ? 397 TRP E CZ3   1 
ATOM   6413  C  CH2   . TRP B 1 397 ? 405.078 375.048 268.449 1.00 100.00 ? 397 TRP E CH2   1 
ATOM   6414  N  N     . TYR B 1 398 ? 408.010 376.342 261.005 1.00 93.44  ? 398 TYR E N     1 
ATOM   6415  C  CA    . TYR B 1 398 ? 408.582 375.911 259.736 1.00 93.65  ? 398 TYR E CA    1 
ATOM   6416  C  C     . TYR B 1 398 ? 410.073 375.639 259.877 1.00 95.41  ? 398 TYR E C     1 
ATOM   6417  O  O     . TYR B 1 398 ? 410.610 374.730 259.235 1.00 99.28  ? 398 TYR E O     1 
ATOM   6418  C  CB    . TYR B 1 398 ? 408.322 376.966 258.662 1.00 89.39  ? 398 TYR E CB    1 
ATOM   6419  C  CG    . TYR B 1 398 ? 406.872 377.067 258.239 1.00 90.56  ? 398 TYR E CG    1 
ATOM   6420  C  CD1   . TYR B 1 398 ? 405.936 377.712 259.036 1.00 91.93  ? 398 TYR E CD1   1 
ATOM   6421  C  CD2   . TYR B 1 398 ? 406.444 376.531 257.036 1.00 96.64  ? 398 TYR E CD2   1 
ATOM   6422  C  CE1   . TYR B 1 398 ? 404.617 377.805 258.653 1.00 92.67  ? 398 TYR E CE1   1 
ATOM   6423  C  CE2   . TYR B 1 398 ? 405.126 376.623 256.644 1.00 95.91  ? 398 TYR E CE2   1 
ATOM   6424  C  CZ    . TYR B 1 398 ? 404.218 377.260 257.458 1.00 91.45  ? 398 TYR E CZ    1 
ATOM   6425  O  OH    . TYR B 1 398 ? 402.902 377.356 257.074 1.00 94.68  ? 398 TYR E OH    1 
ATOM   6426  N  N     . THR B 1 399 ? 410.758 376.420 260.713 1.00 90.29  ? 399 THR E N     1 
ATOM   6427  C  CA    . THR B 1 399 ? 412.192 376.237 260.896 1.00 84.82  ? 399 THR E CA    1 
ATOM   6428  C  C     . THR B 1 399 ? 412.505 374.975 261.690 1.00 84.06  ? 399 THR E C     1 
ATOM   6429  O  O     . THR B 1 399 ? 413.578 374.388 261.513 1.00 86.20  ? 399 THR E O     1 
ATOM   6430  C  CB    . THR B 1 399 ? 412.791 377.459 261.590 1.00 86.14  ? 399 THR E CB    1 
ATOM   6431  O  OG1   . THR B 1 399 ? 412.300 378.654 260.970 1.00 89.81  ? 399 THR E OG1   1 
ATOM   6432  C  CG2   . THR B 1 399 ? 414.311 377.439 261.504 1.00 86.39  ? 399 THR E CG2   1 
ATOM   6433  N  N     . GLY B 1 400 ? 411.598 374.553 262.574 1.00 89.09  ? 400 GLY E N     1 
ATOM   6434  C  CA    . GLY B 1 400 ? 411.811 373.319 263.307 1.00 91.14  ? 400 GLY E CA    1 
ATOM   6435  C  C     . GLY B 1 400 ? 411.869 372.103 262.407 1.00 95.15  ? 400 GLY E C     1 
ATOM   6436  O  O     . GLY B 1 400 ? 412.602 371.152 262.690 1.00 103.08 ? 400 GLY E O     1 
ATOM   6437  N  N     . GLU B 1 401 ? 411.110 372.116 261.313 1.00 102.75 ? 401 GLU E N     1 
ATOM   6438  C  CA    . GLU B 1 401 ? 411.072 371.008 260.369 1.00 108.09 ? 401 GLU E CA    1 
ATOM   6439  C  C     . GLU B 1 401 ? 412.177 371.071 259.317 1.00 112.72 ? 401 GLU E C     1 
ATOM   6440  O  O     . GLU B 1 401 ? 412.119 370.315 258.342 1.00 113.10 ? 401 GLU E O     1 
ATOM   6441  C  CB    . GLU B 1 401 ? 409.705 370.950 259.680 1.00 107.03 ? 401 GLU E CB    1 
ATOM   6442  C  CG    . GLU B 1 401 ? 408.501 370.845 260.619 1.00 108.49 ? 401 GLU E CG    1 
ATOM   6443  C  CD    . GLU B 1 401 ? 408.505 369.575 261.452 1.00 114.17 ? 401 GLU E CD    1 
ATOM   6444  O  OE1   . GLU B 1 401 ? 409.344 369.460 262.370 1.00 112.66 ? 401 GLU E OE1   1 
ATOM   6445  O  OE2   . GLU B 1 401 ? 407.682 368.679 261.178 1.00 113.47 ? 401 GLU E OE2   1 
ATOM   6446  N  N     . GLY B 1 402 ? 413.162 371.963 259.472 1.00 106.20 ? 402 GLY E N     1 
ATOM   6447  C  CA    . GLY B 1 402 ? 414.425 371.893 258.753 1.00 101.79 ? 402 GLY E CA    1 
ATOM   6448  C  C     . GLY B 1 402 ? 414.695 373.075 257.842 1.00 103.06 ? 402 GLY E C     1 
ATOM   6449  O  O     . GLY B 1 402 ? 415.854 373.473 257.686 1.00 105.46 ? 402 GLY E O     1 
ATOM   6450  N  N     . MET B 1 403 ? 413.655 373.639 257.231 1.00 105.66 ? 403 MET E N     1 
ATOM   6451  C  CA    . MET B 1 403 ? 413.879 374.676 256.234 1.00 108.68 ? 403 MET E CA    1 
ATOM   6452  C  C     . MET B 1 403 ? 414.387 375.958 256.891 1.00 103.15 ? 403 MET E C     1 
ATOM   6453  O  O     . MET B 1 403 ? 414.237 376.175 258.096 1.00 101.67 ? 403 MET E O     1 
ATOM   6454  C  CB    . MET B 1 403 ? 412.601 374.948 255.431 1.00 111.34 ? 403 MET E CB    1 
ATOM   6455  C  CG    . MET B 1 403 ? 411.619 375.965 256.039 1.00 111.12 ? 403 MET E CG    1 
ATOM   6456  S  SD    . MET B 1 403 ? 409.991 375.998 255.261 1.00 115.17 ? 403 MET E SD    1 
ATOM   6457  C  CE    . MET B 1 403 ? 410.399 375.994 253.522 1.00 108.60 ? 403 MET E CE    1 
ATOM   6458  N  N     . ASP B 1 404 ? 414.993 376.811 256.068 1.00 119.16 ? 404 ASP E N     1 
ATOM   6459  C  CA    . ASP B 1 404 ? 415.594 378.066 256.493 1.00 124.71 ? 404 ASP E CA    1 
ATOM   6460  C  C     . ASP B 1 404 ? 414.707 379.245 256.113 1.00 127.74 ? 404 ASP E C     1 
ATOM   6461  O  O     . ASP B 1 404 ? 413.790 379.132 255.298 1.00 130.29 ? 404 ASP E O     1 
ATOM   6462  C  CB    . ASP B 1 404 ? 416.976 378.244 255.859 1.00 125.12 ? 404 ASP E CB    1 
ATOM   6463  C  CG    . ASP B 1 404 ? 417.893 377.068 256.119 1.00 129.20 ? 404 ASP E CG    1 
ATOM   6464  O  OD1   . ASP B 1 404 ? 417.822 376.487 257.222 1.00 129.90 ? 404 ASP E OD1   1 
ATOM   6465  O  OD2   . ASP B 1 404 ? 418.686 376.724 255.219 1.00 129.81 ? 404 ASP E OD2   1 
ATOM   6466  N  N     . GLU B 1 405 ? 415.001 380.392 256.727 1.00 126.28 ? 405 GLU E N     1 
ATOM   6467  C  CA    . GLU B 1 405 ? 414.326 381.635 256.374 1.00 124.90 ? 405 GLU E CA    1 
ATOM   6468  C  C     . GLU B 1 405 ? 414.705 382.122 254.979 1.00 123.55 ? 405 GLU E C     1 
ATOM   6469  O  O     . GLU B 1 405 ? 413.947 382.893 254.370 1.00 125.35 ? 405 GLU E O     1 
ATOM   6470  C  CB    . GLU B 1 405 ? 414.662 382.702 257.419 1.00 125.59 ? 405 GLU E CB    1 
ATOM   6471  C  CG    . GLU B 1 405 ? 413.836 383.976 257.327 1.00 130.61 ? 405 GLU E CG    1 
ATOM   6472  C  CD    . GLU B 1 405 ? 414.199 384.985 258.398 1.00 131.40 ? 405 GLU E CD    1 
ATOM   6473  O  OE1   . GLU B 1 405 ? 414.912 384.612 259.352 1.00 128.26 ? 405 GLU E OE1   1 
ATOM   6474  O  OE2   . GLU B 1 405 ? 413.767 386.150 258.286 1.00 127.11 ? 405 GLU E OE2   1 
ATOM   6475  N  N     . MET B 1 406 ? 415.865 381.703 254.466 1.00 119.66 ? 406 MET E N     1 
ATOM   6476  C  CA    . MET B 1 406 ? 416.262 382.104 253.124 1.00 120.28 ? 406 MET E CA    1 
ATOM   6477  C  C     . MET B 1 406 ? 415.288 381.563 252.085 1.00 123.35 ? 406 MET E C     1 
ATOM   6478  O  O     . MET B 1 406 ? 415.055 382.202 251.054 1.00 128.67 ? 406 MET E O     1 
ATOM   6479  C  CB    . MET B 1 406 ? 417.685 381.611 252.829 1.00 119.94 ? 406 MET E CB    1 
ATOM   6480  C  CG    . MET B 1 406 ? 418.426 382.241 251.625 1.00 122.66 ? 406 MET E CG    1 
ATOM   6481  S  SD    . MET B 1 406 ? 418.605 384.039 251.336 1.00 135.42 ? 406 MET E SD    1 
ATOM   6482  C  CE    . MET B 1 406 ? 418.182 384.872 252.874 1.00 127.62 ? 406 MET E CE    1 
ATOM   6483  N  N     . GLU B 1 407 ? 414.704 380.389 252.339 1.00 121.76 ? 407 GLU E N     1 
ATOM   6484  C  CA    . GLU B 1 407 ? 413.678 379.876 251.439 1.00 123.76 ? 407 GLU E CA    1 
ATOM   6485  C  C     . GLU B 1 407 ? 412.452 380.781 251.424 1.00 126.27 ? 407 GLU E C     1 
ATOM   6486  O  O     . GLU B 1 407 ? 411.859 381.015 250.363 1.00 131.57 ? 407 GLU E O     1 
ATOM   6487  C  CB    . GLU B 1 407 ? 413.290 378.458 251.843 1.00 124.11 ? 407 GLU E CB    1 
ATOM   6488  C  CG    . GLU B 1 407 ? 412.217 377.850 250.951 1.00 128.37 ? 407 GLU E CG    1 
ATOM   6489  C  CD    . GLU B 1 407 ? 412.350 376.345 250.801 1.00 128.62 ? 407 GLU E CD    1 
ATOM   6490  O  OE1   . GLU B 1 407 ? 412.871 375.691 251.729 1.00 125.69 ? 407 GLU E OE1   1 
ATOM   6491  O  OE2   . GLU B 1 407 ? 411.947 375.817 249.744 1.00 128.86 ? 407 GLU E OE2   1 
ATOM   6492  N  N     . PHE B 1 408 ? 412.054 381.298 252.591 1.00 107.63 ? 408 PHE E N     1 
ATOM   6493  C  CA    . PHE B 1 408 ? 410.931 382.231 252.645 1.00 105.25 ? 408 PHE E CA    1 
ATOM   6494  C  C     . PHE B 1 408 ? 411.235 383.496 251.854 1.00 108.51 ? 408 PHE E C     1 
ATOM   6495  O  O     . PHE B 1 408 ? 410.391 383.981 251.086 1.00 114.14 ? 408 PHE E O     1 
ATOM   6496  C  CB    . PHE B 1 408 ? 410.611 382.589 254.096 1.00 104.00 ? 408 PHE E CB    1 
ATOM   6497  C  CG    . PHE B 1 408 ? 409.849 381.531 254.831 1.00 104.86 ? 408 PHE E CG    1 
ATOM   6498  C  CD1   . PHE B 1 408 ? 410.472 380.369 255.242 1.00 107.38 ? 408 PHE E CD1   1 
ATOM   6499  C  CD2   . PHE B 1 408 ? 408.510 381.707 255.129 1.00 108.11 ? 408 PHE E CD2   1 
ATOM   6500  C  CE1   . PHE B 1 408 ? 409.772 379.401 255.922 1.00 110.20 ? 408 PHE E CE1   1 
ATOM   6501  C  CE2   . PHE B 1 408 ? 407.807 380.741 255.808 1.00 110.33 ? 408 PHE E CE2   1 
ATOM   6502  C  CZ    . PHE B 1 408 ? 408.439 379.589 256.206 1.00 110.47 ? 408 PHE E CZ    1 
ATOM   6503  N  N     . THR B 1 409 ? 412.443 384.039 252.023 1.00 107.09 ? 409 THR E N     1 
ATOM   6504  C  CA    . THR B 1 409 ? 412.802 385.247 251.281 1.00 107.38 ? 409 THR E CA    1 
ATOM   6505  C  C     . THR B 1 409 ? 412.864 384.976 249.781 1.00 110.19 ? 409 THR E C     1 
ATOM   6506  O  O     . THR B 1 409 ? 412.460 385.823 248.978 1.00 109.54 ? 409 THR E O     1 
ATOM   6507  C  CB    . THR B 1 409 ? 414.138 385.813 251.757 1.00 107.52 ? 409 THR E CB    1 
ATOM   6508  O  OG1   . THR B 1 409 ? 415.185 384.875 251.483 1.00 112.12 ? 409 THR E OG1   1 
ATOM   6509  C  CG2   . THR B 1 409 ? 414.101 386.126 253.243 1.00 108.05 ? 409 THR E CG2   1 
ATOM   6510  N  N     . GLU B 1 410 ? 413.373 383.808 249.384 1.00 119.12 ? 410 GLU E N     1 
ATOM   6511  C  CA    . GLU B 1 410 ? 413.433 383.466 247.967 1.00 117.50 ? 410 GLU E CA    1 
ATOM   6512  C  C     . GLU B 1 410 ? 412.038 383.321 247.376 1.00 117.12 ? 410 GLU E C     1 
ATOM   6513  O  O     . GLU B 1 410 ? 411.791 383.748 246.242 1.00 118.87 ? 410 GLU E O     1 
ATOM   6514  C  CB    . GLU B 1 410 ? 414.228 382.177 247.773 1.00 119.27 ? 410 GLU E CB    1 
ATOM   6515  C  CG    . GLU B 1 410 ? 415.735 382.361 247.845 1.00 120.58 ? 410 GLU E CG    1 
ATOM   6516  C  CD    . GLU B 1 410 ? 416.488 381.058 247.668 1.00 123.99 ? 410 GLU E CD    1 
ATOM   6517  O  OE1   . GLU B 1 410 ? 415.910 379.990 247.961 1.00 122.03 ? 410 GLU E OE1   1 
ATOM   6518  O  OE2   . GLU B 1 410 ? 417.659 381.100 247.236 1.00 124.41 ? 410 GLU E OE2   1 
ATOM   6519  N  N     . ALA B 1 411 ? 411.116 382.708 248.123 1.00 110.89 ? 411 ALA E N     1 
ATOM   6520  C  CA    . ALA B 1 411 ? 409.739 382.597 247.655 1.00 110.44 ? 411 ALA E CA    1 
ATOM   6521  C  C     . ALA B 1 411 ? 409.100 383.971 247.506 1.00 110.44 ? 411 ALA E C     1 
ATOM   6522  O  O     . ALA B 1 411 ? 408.382 384.227 246.531 1.00 117.44 ? 411 ALA E O     1 
ATOM   6523  C  CB    . ALA B 1 411 ? 408.929 381.729 248.616 1.00 110.48 ? 411 ALA E CB    1 
ATOM   6524  N  N     . GLU B 1 412 ? 409.353 384.870 248.461 1.00 112.33 ? 412 GLU E N     1 
ATOM   6525  C  CA    . GLU B 1 412 ? 408.824 386.227 248.352 1.00 114.27 ? 412 GLU E CA    1 
ATOM   6526  C  C     . GLU B 1 412 ? 409.411 386.949 247.144 1.00 114.98 ? 412 GLU E C     1 
ATOM   6527  O  O     . GLU B 1 412 ? 408.696 387.665 246.431 1.00 115.91 ? 412 GLU E O     1 
ATOM   6528  C  CB    . GLU B 1 412 ? 409.110 386.999 249.643 1.00 117.78 ? 412 GLU E CB    1 
ATOM   6529  C  CG    . GLU B 1 412 ? 408.720 388.481 249.644 1.00 118.14 ? 412 GLU E CG    1 
ATOM   6530  C  CD    . GLU B 1 412 ? 407.271 388.721 249.261 1.00 120.41 ? 412 GLU E CD    1 
ATOM   6531  O  OE1   . GLU B 1 412 ? 406.436 387.819 249.479 1.00 121.42 ? 412 GLU E OE1   1 
ATOM   6532  O  OE2   . GLU B 1 412 ? 406.969 389.813 248.736 1.00 119.80 ? 412 GLU E OE2   1 
ATOM   6533  N  N     . SER B 1 413 ? 410.712 386.776 246.902 1.00 107.31 ? 413 SER E N     1 
ATOM   6534  C  CA    . SER B 1 413 ? 411.350 387.405 245.750 1.00 108.49 ? 413 SER E CA    1 
ATOM   6535  C  C     . SER B 1 413 ? 410.770 386.877 244.444 1.00 110.66 ? 413 SER E C     1 
ATOM   6536  O  O     . SER B 1 413 ? 410.522 387.647 243.508 1.00 112.42 ? 413 SER E O     1 
ATOM   6537  C  CB    . SER B 1 413 ? 412.859 387.169 245.802 1.00 104.68 ? 413 SER E CB    1 
ATOM   6538  O  OG    . SER B 1 413 ? 413.512 387.786 244.708 1.00 107.01 ? 413 SER E OG    1 
ATOM   6539  N  N     . ASN B 1 414 ? 410.539 385.566 244.364 1.00 115.49 ? 414 ASN E N     1 
ATOM   6540  C  CA    . ASN B 1 414 ? 409.952 385.001 243.154 1.00 117.17 ? 414 ASN E CA    1 
ATOM   6541  C  C     . ASN B 1 414 ? 408.514 385.465 242.960 1.00 116.09 ? 414 ASN E C     1 
ATOM   6542  O  O     . ASN B 1 414 ? 408.089 385.691 241.823 1.00 117.61 ? 414 ASN E O     1 
ATOM   6543  C  CB    . ASN B 1 414 ? 410.019 383.475 243.196 1.00 114.41 ? 414 ASN E CB    1 
ATOM   6544  C  CG    . ASN B 1 414 ? 409.764 382.843 241.840 1.00 115.13 ? 414 ASN E CG    1 
ATOM   6545  O  OD1   . ASN B 1 414 ? 409.541 383.539 240.850 1.00 116.80 ? 414 ASN E OD1   1 
ATOM   6546  N  ND2   . ASN B 1 414 ? 409.801 381.518 241.787 1.00 113.55 ? 414 ASN E ND2   1 
ATOM   6547  N  N     . MET B 1 415 ? 407.752 385.618 244.044 1.00 112.54 ? 415 MET E N     1 
ATOM   6548  C  CA    . MET B 1 415 ? 406.393 386.135 243.913 1.00 107.99 ? 415 MET E CA    1 
ATOM   6549  C  C     . MET B 1 415 ? 406.404 387.586 243.453 1.00 115.53 ? 415 MET E C     1 
ATOM   6550  O  O     . MET B 1 415 ? 405.557 387.995 242.649 1.00 117.82 ? 415 MET E O     1 
ATOM   6551  C  CB    . MET B 1 415 ? 405.655 386.005 245.245 1.00 116.30 ? 415 MET E CB    1 
ATOM   6552  C  CG    . MET B 1 415 ? 405.046 384.624 245.523 1.00 118.72 ? 415 MET E CG    1 
ATOM   6553  S  SD    . MET B 1 415 ? 403.384 384.606 246.242 1.00 133.25 ? 415 MET E SD    1 
ATOM   6554  C  CE    . MET B 1 415 ? 402.410 385.535 245.059 1.00 118.19 ? 415 MET E CE    1 
ATOM   6555  N  N     . ASN B 1 416 ? 407.354 388.380 243.954 1.00 120.86 ? 416 ASN E N     1 
ATOM   6556  C  CA    . ASN B 1 416 ? 407.500 389.751 243.477 1.00 119.94 ? 416 ASN E CA    1 
ATOM   6557  C  C     . ASN B 1 416 ? 407.844 389.775 241.994 1.00 120.75 ? 416 ASN E C     1 
ATOM   6558  O  O     . ASN B 1 416 ? 407.312 390.596 241.236 1.00 123.14 ? 416 ASN E O     1 
ATOM   6559  C  CB    . ASN B 1 416 ? 408.580 390.474 244.281 1.00 124.55 ? 416 ASN E CB    1 
ATOM   6560  C  CG    . ASN B 1 416 ? 408.060 391.028 245.590 1.00 129.99 ? 416 ASN E CG    1 
ATOM   6561  O  OD1   . ASN B 1 416 ? 407.498 392.121 245.636 1.00 127.80 ? 416 ASN E OD1   1 
ATOM   6562  N  ND2   . ASN B 1 416 ? 408.262 390.281 246.667 1.00 130.54 ? 416 ASN E ND2   1 
ATOM   6563  N  N     . ASP B 1 417 ? 408.730 388.872 241.565 1.00 115.13 ? 417 ASP E N     1 
ATOM   6564  C  CA    . ASP B 1 417 ? 409.066 388.770 240.149 1.00 114.26 ? 417 ASP E CA    1 
ATOM   6565  C  C     . ASP B 1 417 ? 407.845 388.392 239.322 1.00 110.97 ? 417 ASP E C     1 
ATOM   6566  O  O     . ASP B 1 417 ? 407.645 388.920 238.225 1.00 110.91 ? 417 ASP E O     1 
ATOM   6567  C  CB    . ASP B 1 417 ? 410.182 387.745 239.947 1.00 114.87 ? 417 ASP E CB    1 
ATOM   6568  C  CG    . ASP B 1 417 ? 411.481 388.155 240.612 1.00 117.65 ? 417 ASP E CG    1 
ATOM   6569  O  OD1   . ASP B 1 417 ? 411.638 389.349 240.939 1.00 112.93 ? 417 ASP E OD1   1 
ATOM   6570  O  OD2   . ASP B 1 417 ? 412.348 387.279 240.807 1.00 120.47 ? 417 ASP E OD2   1 
ATOM   6571  N  N     . LEU B 1 418 ? 407.017 387.481 239.833 1.00 103.60 ? 418 LEU E N     1 
ATOM   6572  C  CA    . LEU B 1 418 ? 405.817 387.075 239.107 1.00 103.75 ? 418 LEU E CA    1 
ATOM   6573  C  C     . LEU B 1 418 ? 404.823 388.226 238.981 1.00 105.58 ? 418 LEU E C     1 
ATOM   6574  O  O     . LEU B 1 418 ? 404.227 388.426 237.915 1.00 106.13 ? 418 LEU E O     1 
ATOM   6575  C  CB    . LEU B 1 418 ? 405.168 385.882 239.807 1.00 107.36 ? 418 LEU E CB    1 
ATOM   6576  C  CG    . LEU B 1 418 ? 404.020 385.172 239.084 1.00 103.99 ? 418 LEU E CG    1 
ATOM   6577  C  CD1   . LEU B 1 418 ? 404.504 384.485 237.816 1.00 107.07 ? 418 LEU E CD1   1 
ATOM   6578  C  CD2   . LEU B 1 418 ? 403.359 384.172 240.016 1.00 101.07 ? 418 LEU E CD2   1 
ATOM   6579  N  N     . VAL B 1 419 ? 404.626 388.989 240.057 1.00 114.25 ? 419 VAL E N     1 
ATOM   6580  C  CA    . VAL B 1 419 ? 403.691 390.110 239.994 1.00 112.69 ? 419 VAL E CA    1 
ATOM   6581  C  C     . VAL B 1 419 ? 404.218 391.188 239.054 1.00 117.53 ? 419 VAL E C     1 
ATOM   6582  O  O     . VAL B 1 419 ? 403.450 391.809 238.309 1.00 116.12 ? 419 VAL E O     1 
ATOM   6583  C  CB    . VAL B 1 419 ? 403.409 390.666 241.402 1.00 115.44 ? 419 VAL E CB    1 
ATOM   6584  C  CG1   . VAL B 1 419 ? 402.569 391.939 241.318 1.00 114.62 ? 419 VAL E CG1   1 
ATOM   6585  C  CG2   . VAL B 1 419 ? 402.682 389.626 242.251 1.00 113.89 ? 419 VAL E CG2   1 
ATOM   6586  N  N     . SER B 1 420 ? 405.533 391.425 239.062 1.00 112.89 ? 420 SER E N     1 
ATOM   6587  C  CA    . SER B 1 420 ? 406.110 392.370 238.110 1.00 109.83 ? 420 SER E CA    1 
ATOM   6588  C  C     . SER B 1 420 ? 405.955 391.870 236.678 1.00 108.81 ? 420 SER E C     1 
ATOM   6589  O  O     . SER B 1 420 ? 405.697 392.658 235.759 1.00 108.44 ? 420 SER E O     1 
ATOM   6590  C  CB    . SER B 1 420 ? 407.584 392.612 238.434 1.00 106.61 ? 420 SER E CB    1 
ATOM   6591  O  OG    . SER B 1 420 ? 408.417 391.752 237.679 1.00 106.16 ? 420 SER E OG    1 
ATOM   6592  N  N     . GLU B 1 421 ? 406.117 390.562 236.473 1.00 115.50 ? 421 GLU E N     1 
ATOM   6593  C  CA    . GLU B 1 421 ? 405.957 389.983 235.146 1.00 116.11 ? 421 GLU E CA    1 
ATOM   6594  C  C     . GLU B 1 421 ? 404.519 390.079 234.663 1.00 115.19 ? 421 GLU E C     1 
ATOM   6595  O  O     . GLU B 1 421 ? 404.282 390.139 233.456 1.00 116.36 ? 421 GLU E O     1 
ATOM   6596  C  CB    . GLU B 1 421 ? 406.411 388.525 235.154 1.00 116.20 ? 421 GLU E CB    1 
ATOM   6597  C  CG    . GLU B 1 421 ? 407.921 388.354 235.075 1.00 118.21 ? 421 GLU E CG    1 
ATOM   6598  C  CD    . GLU B 1 421 ? 408.369 386.915 235.264 1.00 121.02 ? 421 GLU E CD    1 
ATOM   6599  O  OE1   . GLU B 1 421 ? 407.563 386.086 235.735 1.00 123.33 ? 421 GLU E OE1   1 
ATOM   6600  O  OE2   . GLU B 1 421 ? 409.536 386.613 234.940 1.00 120.67 ? 421 GLU E OE2   1 
ATOM   6601  N  N     . TYR B 1 422 ? 403.551 390.059 235.578 1.00 107.54 ? 422 TYR E N     1 
ATOM   6602  C  CA    . TYR B 1 422 ? 402.166 390.301 235.175 1.00 106.22 ? 422 TYR E CA    1 
ATOM   6603  C  C     . TYR B 1 422 ? 401.911 391.780 234.910 1.00 108.40 ? 422 TYR E C     1 
ATOM   6604  O  O     . TYR B 1 422 ? 401.144 392.126 234.005 1.00 109.31 ? 422 TYR E O     1 
ATOM   6605  C  CB    . TYR B 1 422 ? 401.190 389.782 236.234 1.00 107.97 ? 422 TYR E CB    1 
ATOM   6606  C  CG    . TYR B 1 422 ? 400.610 388.422 235.916 1.00 107.17 ? 422 TYR E CG    1 
ATOM   6607  C  CD1   . TYR B 1 422 ? 399.679 388.263 234.897 1.00 109.14 ? 422 TYR E CD1   1 
ATOM   6608  C  CD2   . TYR B 1 422 ? 400.991 387.298 236.632 1.00 105.14 ? 422 TYR E CD2   1 
ATOM   6609  C  CE1   . TYR B 1 422 ? 399.151 387.027 234.600 1.00 108.93 ? 422 TYR E CE1   1 
ATOM   6610  C  CE2   . TYR B 1 422 ? 400.463 386.057 236.344 1.00 102.06 ? 422 TYR E CE2   1 
ATOM   6611  C  CZ    . TYR B 1 422 ? 399.547 385.927 235.325 1.00 107.46 ? 422 TYR E CZ    1 
ATOM   6612  O  OH    . TYR B 1 422 ? 399.018 384.693 235.032 1.00 110.64 ? 422 TYR E OH    1 
ATOM   6613  N  N     . GLN B 1 423 ? 402.543 392.664 235.684 1.00 123.67 ? 423 GLN E N     1 
ATOM   6614  C  CA    . GLN B 1 423 ? 402.280 394.092 235.542 1.00 126.02 ? 423 GLN E CA    1 
ATOM   6615  C  C     . GLN B 1 423 ? 402.926 394.674 234.288 1.00 126.29 ? 423 GLN E C     1 
ATOM   6616  O  O     . GLN B 1 423 ? 402.431 395.672 233.746 1.00 127.04 ? 423 GLN E O     1 
ATOM   6617  C  CB    . GLN B 1 423 ? 402.769 394.829 236.795 1.00 128.38 ? 423 GLN E CB    1 
ATOM   6618  C  CG    . GLN B 1 423 ? 402.717 396.363 236.745 1.00 133.63 ? 423 GLN E CG    1 
ATOM   6619  C  CD    . GLN B 1 423 ? 401.361 396.913 236.338 1.00 132.01 ? 423 GLN E CD    1 
ATOM   6620  O  OE1   . GLN B 1 423 ? 400.332 396.263 236.514 1.00 123.59 ? 423 GLN E OE1   1 
ATOM   6621  N  NE2   . GLN B 1 423 ? 401.357 398.121 235.786 1.00 134.10 ? 423 GLN E NE2   1 
ATOM   6622  N  N     . GLN B 1 424 ? 404.035 394.093 233.823 1.00 122.09 ? 424 GLN E N     1 
ATOM   6623  C  CA    . GLN B 1 424 ? 404.737 394.697 232.694 1.00 122.81 ? 424 GLN E CA    1 
ATOM   6624  C  C     . GLN B 1 424 ? 403.924 394.596 231.408 1.00 117.75 ? 424 GLN E C     1 
ATOM   6625  O  O     . GLN B 1 424 ? 403.997 395.490 230.559 1.00 123.08 ? 424 GLN E O     1 
ATOM   6626  C  CB    . GLN B 1 424 ? 406.122 394.071 232.514 1.00 122.21 ? 424 GLN E CB    1 
ATOM   6627  C  CG    . GLN B 1 424 ? 406.143 392.589 232.197 1.00 124.13 ? 424 GLN E CG    1 
ATOM   6628  C  CD    . GLN B 1 424 ? 407.551 392.027 232.144 1.00 126.96 ? 424 GLN E CD    1 
ATOM   6629  O  OE1   . GLN B 1 424 ? 408.494 392.634 232.650 1.00 124.65 ? 424 GLN E OE1   1 
ATOM   6630  N  NE2   . GLN B 1 424 ? 407.698 390.859 231.532 1.00 129.08 ? 424 GLN E NE2   1 
ATOM   6631  N  N     . TYR B 1 425 ? 403.140 393.525 231.241 1.00 103.60 ? 425 TYR E N     1 
ATOM   6632  C  CA    . TYR B 1 425 ? 402.300 393.422 230.048 1.00 111.27 ? 425 TYR E CA    1 
ATOM   6633  C  C     . TYR B 1 425 ? 401.067 394.310 230.149 1.00 116.24 ? 425 TYR E C     1 
ATOM   6634  O  O     . TYR B 1 425 ? 400.535 394.742 229.120 1.00 116.57 ? 425 TYR E O     1 
ATOM   6635  C  CB    . TYR B 1 425 ? 401.902 391.969 229.801 1.00 105.97 ? 425 TYR E CB    1 
ATOM   6636  C  CG    . TYR B 1 425 ? 403.101 391.073 229.628 1.00 111.15 ? 425 TYR E CG    1 
ATOM   6637  C  CD1   . TYR B 1 425 ? 403.911 391.161 228.505 1.00 116.31 ? 425 TYR E CD1   1 
ATOM   6638  C  CD2   . TYR B 1 425 ? 403.424 390.141 230.590 1.00 112.80 ? 425 TYR E CD2   1 
ATOM   6639  C  CE1   . TYR B 1 425 ? 405.017 390.344 228.357 1.00 115.79 ? 425 TYR E CE1   1 
ATOM   6640  C  CE2   . TYR B 1 425 ? 404.521 389.325 230.457 1.00 119.14 ? 425 TYR E CE2   1 
ATOM   6641  C  CZ    . TYR B 1 425 ? 405.314 389.425 229.340 1.00 118.67 ? 425 TYR E CZ    1 
ATOM   6642  O  OH    . TYR B 1 425 ? 406.405 388.595 229.229 1.00 114.73 ? 425 TYR E OH    1 
ATOM   6643  N  N     . GLN B 1 426 ? 400.593 394.587 231.366 1.00 125.00 ? 426 GLN E N     1 
ATOM   6644  C  CA    . GLN B 1 426 ? 399.607 395.650 231.538 1.00 125.65 ? 426 GLN E CA    1 
ATOM   6645  C  C     . GLN B 1 426 ? 400.179 396.988 231.095 1.00 129.90 ? 426 GLN E C     1 
ATOM   6646  O  O     . GLN B 1 426 ? 399.507 397.768 230.411 1.00 120.22 ? 426 GLN E O     1 
ATOM   6647  C  CB    . GLN B 1 426 ? 399.158 395.733 232.998 1.00 128.65 ? 426 GLN E CB    1 
ATOM   6648  C  CG    . GLN B 1 426 ? 398.453 394.504 233.535 1.00 129.87 ? 426 GLN E CG    1 
ATOM   6649  C  CD    . GLN B 1 426 ? 396.956 394.698 233.598 1.00 122.90 ? 426 GLN E CD    1 
ATOM   6650  O  OE1   . GLN B 1 426 ? 396.372 394.770 234.679 1.00 117.99 ? 426 GLN E OE1   1 
ATOM   6651  N  NE2   . GLN B 1 426 ? 396.327 394.810 232.438 1.00 123.42 ? 426 GLN E NE2   1 
ATOM   6652  N  N     . ASP B 1 427 ? 401.424 397.266 231.476 1.00 154.26 ? 427 ASP E N     1 
ATOM   6653  C  CA    . ASP B 1 427 ? 402.083 398.506 231.087 1.00 152.89 ? 427 ASP E CA    1 
ATOM   6654  C  C     . ASP B 1 427 ? 402.519 398.526 229.625 1.00 151.35 ? 427 ASP E C     1 
ATOM   6655  O  O     . ASP B 1 427 ? 402.828 399.605 229.107 1.00 155.23 ? 427 ASP E O     1 
ATOM   6656  C  CB    . ASP B 1 427 ? 403.302 398.749 231.981 1.00 151.13 ? 427 ASP E CB    1 
ATOM   6657  N  N     . ALA B 1 428 ? 402.554 397.380 228.951 1.00 130.87 ? 428 ALA E N     1 
ATOM   6658  C  CA    . ALA B 1 428 ? 403.077 397.324 227.593 1.00 133.30 ? 428 ALA E CA    1 
ATOM   6659  C  C     . ALA B 1 428 ? 402.114 397.971 226.607 1.00 136.18 ? 428 ALA E C     1 
ATOM   6660  O  O     . ALA B 1 428 ? 400.897 397.982 226.815 1.00 132.23 ? 428 ALA E O     1 
ATOM   6661  C  CB    . ALA B 1 428 ? 403.341 395.876 227.188 1.00 129.98 ? 428 ALA E CB    1 
ATOM   6662  N  N     . THR B 1 429 ? 402.671 398.512 225.528 1.00 133.72 ? 429 THR E N     1 
ATOM   6663  C  CA    . THR B 1 429 ? 401.884 399.142 224.474 1.00 129.76 ? 429 THR E CA    1 
ATOM   6664  C  C     . THR B 1 429 ? 402.605 399.034 223.135 1.00 124.57 ? 429 THR E C     1 
ATOM   6665  O  O     . THR B 1 429 ? 403.727 398.533 223.062 1.00 120.47 ? 429 THR E O     1 
ATOM   6666  C  CB    . THR B 1 429 ? 401.608 400.624 224.784 1.00 128.04 ? 429 THR E CB    1 
ATOM   6667  N  N     . MET C 2 1   ? 393.331 354.275 264.842 1.00 151.07 ? 1   MET A N     1 
ATOM   6668  C  CA    . MET C 2 1   ? 394.599 354.503 264.095 1.00 149.72 ? 1   MET A CA    1 
ATOM   6669  C  C     . MET C 2 1   ? 395.394 355.575 264.832 1.00 147.30 ? 1   MET A C     1 
ATOM   6670  O  O     . MET C 2 1   ? 396.498 355.320 265.311 1.00 147.76 ? 1   MET A O     1 
ATOM   6671  C  CB    . MET C 2 1   ? 394.305 354.928 262.646 1.00 148.98 ? 1   MET A CB    1 
ATOM   6672  C  CG    . MET C 2 1   ? 393.623 353.882 261.713 1.00 149.79 ? 1   MET A CG    1 
ATOM   6673  S  SD    . MET C 2 1   ? 394.443 352.282 261.372 1.00 161.93 ? 1   MET A SD    1 
ATOM   6674  C  CE    . MET C 2 1   ? 395.911 352.693 260.417 1.00 146.77 ? 1   MET A CE    1 
ATOM   6675  N  N     . ARG C 2 2   ? 394.834 356.781 264.884 1.00 130.66 ? 2   ARG A N     1 
ATOM   6676  C  CA    . ARG C 2 2   ? 395.502 357.944 265.453 1.00 127.14 ? 2   ARG A CA    1 
ATOM   6677  C  C     . ARG C 2 2   ? 395.056 358.104 266.898 1.00 128.39 ? 2   ARG A C     1 
ATOM   6678  O  O     . ARG C 2 2   ? 393.861 358.247 267.172 1.00 131.21 ? 2   ARG A O     1 
ATOM   6679  C  CB    . ARG C 2 2   ? 395.211 359.208 264.634 1.00 126.12 ? 2   ARG A CB    1 
ATOM   6680  C  CG    . ARG C 2 2   ? 393.731 359.630 264.508 1.00 128.66 ? 2   ARG A CG    1 
ATOM   6681  C  CD    . ARG C 2 2   ? 393.441 360.377 263.197 1.00 124.48 ? 2   ARG A CD    1 
ATOM   6682  N  NE    . ARG C 2 2   ? 392.012 360.457 262.906 1.00 129.31 ? 2   ARG A NE    1 
ATOM   6683  C  CZ    . ARG C 2 2   ? 391.259 359.459 262.455 1.00 132.86 ? 2   ARG A CZ    1 
ATOM   6684  N  NH1   . ARG C 2 2   ? 391.759 358.257 262.207 1.00 130.85 ? 2   ARG A NH1   1 
ATOM   6685  N  NH2   . ARG C 2 2   ? 389.964 359.674 262.243 1.00 136.09 ? 2   ARG A NH2   1 
ATOM   6686  N  N     . GLU C 2 3   ? 396.021 358.074 267.814 1.00 126.50 ? 3   GLU A N     1 
ATOM   6687  C  CA    . GLU C 2 3   ? 395.774 357.933 269.240 1.00 121.01 ? 3   GLU A CA    1 
ATOM   6688  C  C     . GLU C 2 3   ? 396.121 359.210 269.988 1.00 124.30 ? 3   GLU A C     1 
ATOM   6689  O  O     . GLU C 2 3   ? 396.958 360.005 269.552 1.00 131.40 ? 3   GLU A O     1 
ATOM   6690  C  CB    . GLU C 2 3   ? 396.592 356.779 269.825 1.00 128.37 ? 3   GLU A CB    1 
ATOM   6691  C  CG    . GLU C 2 3   ? 396.024 355.388 269.562 1.00 134.57 ? 3   GLU A CG    1 
ATOM   6692  C  CD    . GLU C 2 3   ? 396.510 354.756 268.275 1.00 134.69 ? 3   GLU A CD    1 
ATOM   6693  O  OE1   . GLU C 2 3   ? 397.727 354.798 267.994 1.00 135.18 ? 3   GLU A OE1   1 
ATOM   6694  O  OE2   . GLU C 2 3   ? 395.665 354.173 267.564 1.00 134.34 ? 3   GLU A OE2   1 
ATOM   6695  N  N     . CYS C 2 4   ? 395.457 359.386 271.129 1.00 125.19 ? 4   CYS A N     1 
ATOM   6696  C  CA    . CYS C 2 4   ? 395.740 360.462 272.066 1.00 130.96 ? 4   CYS A CA    1 
ATOM   6697  C  C     . CYS C 2 4   ? 395.684 359.886 273.470 1.00 128.64 ? 4   CYS A C     1 
ATOM   6698  O  O     . CYS C 2 4   ? 394.681 359.272 273.845 1.00 128.04 ? 4   CYS A O     1 
ATOM   6699  C  CB    . CYS C 2 4   ? 394.731 361.605 271.922 1.00 125.44 ? 4   CYS A CB    1 
ATOM   6700  S  SG    . CYS C 2 4   ? 394.881 362.538 270.387 1.00 137.96 ? 4   CYS A SG    1 
ATOM   6701  N  N     . ILE C 2 5   ? 396.748 360.091 274.240 1.00 109.81 ? 5   ILE A N     1 
ATOM   6702  C  CA    . ILE C 2 5   ? 396.851 359.582 275.603 1.00 104.73 ? 5   ILE A CA    1 
ATOM   6703  C  C     . ILE C 2 5   ? 396.402 360.688 276.547 1.00 109.62 ? 5   ILE A C     1 
ATOM   6704  O  O     . ILE C 2 5   ? 397.041 361.743 276.627 1.00 113.54 ? 5   ILE A O     1 
ATOM   6705  C  CB    . ILE C 2 5   ? 398.280 359.118 275.928 1.00 105.41 ? 5   ILE A CB    1 
ATOM   6706  C  CG1   . ILE C 2 5   ? 398.628 357.850 275.141 1.00 102.61 ? 5   ILE A CG1   1 
ATOM   6707  C  CG2   . ILE C 2 5   ? 398.437 358.843 277.424 1.00 105.98 ? 5   ILE A CG2   1 
ATOM   6708  C  CD1   . ILE C 2 5   ? 400.111 357.650 274.924 1.00 108.87 ? 5   ILE A CD1   1 
ATOM   6709  N  N     . SER C 2 6   ? 395.310 360.442 277.265 1.00 107.58 ? 6   SER A N     1 
ATOM   6710  C  CA    . SER C 2 6   ? 394.795 361.382 278.251 1.00 99.83  ? 6   SER A CA    1 
ATOM   6711  C  C     . SER C 2 6   ? 395.475 361.126 279.587 1.00 102.69 ? 6   SER A C     1 
ATOM   6712  O  O     . SER C 2 6   ? 395.615 359.973 280.005 1.00 112.48 ? 6   SER A O     1 
ATOM   6713  C  CB    . SER C 2 6   ? 393.281 361.239 278.394 1.00 101.46 ? 6   SER A CB    1 
ATOM   6714  O  OG    . SER C 2 6   ? 392.659 361.119 277.128 1.00 107.29 ? 6   SER A OG    1 
ATOM   6715  N  N     . ILE C 2 7   ? 395.911 362.200 280.242 1.00 91.92  ? 7   ILE A N     1 
ATOM   6716  C  CA    . ILE C 2 7   ? 396.519 362.141 281.566 1.00 89.53  ? 7   ILE A CA    1 
ATOM   6717  C  C     . ILE C 2 7   ? 395.793 363.139 282.453 1.00 88.50  ? 7   ILE A C     1 
ATOM   6718  O  O     . ILE C 2 7   ? 395.480 364.253 282.022 1.00 100.00 ? 7   ILE A O     1 
ATOM   6719  C  CB    . ILE C 2 7   ? 398.036 362.431 281.535 1.00 94.87  ? 7   ILE A CB    1 
ATOM   6720  C  CG1   . ILE C 2 7   ? 398.792 361.346 280.755 1.00 100.16 ? 7   ILE A CG1   1 
ATOM   6721  C  CG2   . ILE C 2 7   ? 398.587 362.516 282.951 1.00 94.06  ? 7   ILE A CG2   1 
ATOM   6722  C  CD1   . ILE C 2 7   ? 400.087 361.823 280.147 1.00 100.35 ? 7   ILE A CD1   1 
ATOM   6723  N  N     . HIS C 2 8   ? 395.516 362.727 283.689 1.00 81.56  ? 8   HIS A N     1 
ATOM   6724  C  CA    . HIS C 2 8   ? 394.668 363.471 284.615 1.00 84.31  ? 8   HIS A CA    1 
ATOM   6725  C  C     . HIS C 2 8   ? 395.371 363.532 285.963 1.00 96.35  ? 8   HIS A C     1 
ATOM   6726  O  O     . HIS C 2 8   ? 395.420 362.531 286.685 1.00 106.02 ? 8   HIS A O     1 
ATOM   6727  C  CB    . HIS C 2 8   ? 393.300 362.806 284.726 1.00 95.79  ? 8   HIS A CB    1 
ATOM   6728  C  CG    . HIS C 2 8   ? 392.595 362.670 283.413 1.00 99.71  ? 8   HIS A CG    1 
ATOM   6729  N  ND1   . HIS C 2 8   ? 391.813 363.672 282.881 1.00 97.80  ? 8   HIS A ND1   1 
ATOM   6730  C  CD2   . HIS C 2 8   ? 392.568 361.656 282.516 1.00 100.57 ? 8   HIS A CD2   1 
ATOM   6731  C  CE1   . HIS C 2 8   ? 391.330 363.279 281.716 1.00 96.06  ? 8   HIS A CE1   1 
ATOM   6732  N  NE2   . HIS C 2 8   ? 391.771 362.059 281.472 1.00 92.76  ? 8   HIS A NE2   1 
ATOM   6733  N  N     . VAL C 2 9   ? 395.898 364.709 286.299 1.00 97.77  ? 9   VAL A N     1 
ATOM   6734  C  CA    . VAL C 2 9   ? 396.751 364.916 287.465 1.00 96.88  ? 9   VAL A CA    1 
ATOM   6735  C  C     . VAL C 2 9   ? 396.014 365.808 288.451 1.00 97.07  ? 9   VAL A C     1 
ATOM   6736  O  O     . VAL C 2 9   ? 395.439 366.832 288.063 1.00 101.14 ? 9   VAL A O     1 
ATOM   6737  C  CB    . VAL C 2 9   ? 398.101 365.541 287.074 1.00 95.18  ? 9   VAL A CB    1 
ATOM   6738  C  CG1   . VAL C 2 9   ? 399.126 365.321 288.175 1.00 101.35 ? 9   VAL A CG1   1 
ATOM   6739  C  CG2   . VAL C 2 9   ? 398.603 364.964 285.755 1.00 99.83  ? 9   VAL A CG2   1 
ATOM   6740  N  N     . GLY C 2 10  ? 396.030 365.420 289.721 1.00 101.47 ? 10  GLY A N     1 
ATOM   6741  C  CA    . GLY C 2 10  ? 395.405 366.200 290.765 1.00 105.48 ? 10  GLY A CA    1 
ATOM   6742  C  C     . GLY C 2 10  ? 393.902 366.010 290.795 1.00 101.46 ? 10  GLY A C     1 
ATOM   6743  O  O     . GLY C 2 10  ? 393.299 365.383 289.922 1.00 102.74 ? 10  GLY A O     1 
ATOM   6744  N  N     . GLN C 2 11  ? 393.287 366.580 291.837 1.00 96.71  ? 11  GLN A N     1 
ATOM   6745  C  CA    . GLN C 2 11  ? 391.846 366.442 292.031 1.00 90.34  ? 11  GLN A CA    1 
ATOM   6746  C  C     . GLN C 2 11  ? 391.072 367.053 290.872 1.00 90.74  ? 11  GLN A C     1 
ATOM   6747  O  O     . GLN C 2 11  ? 390.114 366.456 290.368 1.00 101.26 ? 11  GLN A O     1 
ATOM   6748  C  CB    . GLN C 2 11  ? 391.433 367.094 293.350 1.00 97.15  ? 11  GLN A CB    1 
ATOM   6749  C  CG    . GLN C 2 11  ? 389.928 367.182 293.553 1.00 95.45  ? 11  GLN A CG    1 
ATOM   6750  C  CD    . GLN C 2 11  ? 389.539 367.283 295.012 1.00 97.18  ? 11  GLN A CD    1 
ATOM   6751  O  OE1   . GLN C 2 11  ? 390.339 367.691 295.852 1.00 99.35  ? 11  GLN A OE1   1 
ATOM   6752  N  NE2   . GLN C 2 11  ? 388.303 366.916 295.321 1.00 96.94  ? 11  GLN A NE2   1 
ATOM   6753  N  N     . ALA C 2 12  ? 391.487 368.240 290.426 1.00 86.02  ? 12  ALA A N     1 
ATOM   6754  C  CA    . ALA C 2 12  ? 390.802 368.895 289.318 1.00 91.13  ? 12  ALA A CA    1 
ATOM   6755  C  C     . ALA C 2 12  ? 390.927 368.079 288.042 1.00 99.10  ? 12  ALA A C     1 
ATOM   6756  O  O     . ALA C 2 12  ? 389.934 367.864 287.330 1.00 103.74 ? 12  ALA A O     1 
ATOM   6757  C  CB    . ALA C 2 12  ? 391.371 370.295 289.114 1.00 89.32  ? 12  ALA A CB    1 
ATOM   6758  N  N     . GLY C 2 13  ? 392.136 367.588 287.761 1.00 103.87 ? 13  GLY A N     1 
ATOM   6759  C  CA    . GLY C 2 13  ? 392.353 366.802 286.560 1.00 101.53 ? 13  GLY A CA    1 
ATOM   6760  C  C     . GLY C 2 13  ? 391.529 365.531 286.543 1.00 100.89 ? 13  GLY A C     1 
ATOM   6761  O  O     . GLY C 2 13  ? 390.876 365.219 285.548 1.00 104.37 ? 13  GLY A O     1 
ATOM   6762  N  N     . VAL C 2 14  ? 391.522 364.794 287.656 1.00 98.97  ? 14  VAL A N     1 
ATOM   6763  C  CA    . VAL C 2 14  ? 390.792 363.529 287.669 1.00 94.88  ? 14  VAL A CA    1 
ATOM   6764  C  C     . VAL C 2 14  ? 389.284 363.760 287.652 1.00 93.67  ? 14  VAL A C     1 
ATOM   6765  O  O     . VAL C 2 14  ? 388.552 362.993 287.026 1.00 106.13 ? 14  VAL A O     1 
ATOM   6766  C  CB    . VAL C 2 14  ? 391.214 362.638 288.854 1.00 96.19  ? 14  VAL A CB    1 
ATOM   6767  C  CG1   . VAL C 2 14  ? 392.701 362.301 288.778 1.00 101.30 ? 14  VAL A CG1   1 
ATOM   6768  C  CG2   . VAL C 2 14  ? 390.853 363.260 290.182 1.00 106.09 ? 14  VAL A CG2   1 
ATOM   6769  N  N     . GLN C 2 15  ? 388.782 364.787 288.347 1.00 86.15  ? 15  GLN A N     1 
ATOM   6770  C  CA    . GLN C 2 15  ? 387.333 365.009 288.330 1.00 90.58  ? 15  GLN A CA    1 
ATOM   6771  C  C     . GLN C 2 15  ? 386.861 365.419 286.938 1.00 88.92  ? 15  GLN A C     1 
ATOM   6772  O  O     . GLN C 2 15  ? 385.832 364.921 286.439 1.00 95.95  ? 15  GLN A O     1 
ATOM   6773  C  CB    . GLN C 2 15  ? 386.933 366.063 289.365 1.00 91.96  ? 15  GLN A CB    1 
ATOM   6774  C  CG    . GLN C 2 15  ? 386.090 365.507 290.504 1.00 94.17  ? 15  GLN A CG    1 
ATOM   6775  C  CD    . GLN C 2 15  ? 385.822 366.524 291.597 1.00 97.56  ? 15  GLN A CD    1 
ATOM   6776  O  OE1   . GLN C 2 15  ? 386.599 367.455 291.802 1.00 96.88  ? 15  GLN A OE1   1 
ATOM   6777  N  NE2   . GLN C 2 15  ? 384.714 366.348 292.306 1.00 100.12 ? 15  GLN A NE2   1 
ATOM   6778  N  N     . ILE C 2 16  ? 387.622 366.296 286.280 1.00 86.91  ? 16  ILE A N     1 
ATOM   6779  C  CA    . ILE C 2 16  ? 387.312 366.633 284.898 1.00 91.94  ? 16  ILE A CA    1 
ATOM   6780  C  C     . ILE C 2 16  ? 387.448 365.398 284.016 1.00 97.34  ? 16  ILE A C     1 
ATOM   6781  O  O     . ILE C 2 16  ? 386.696 365.228 283.058 1.00 97.22  ? 16  ILE A O     1 
ATOM   6782  C  CB    . ILE C 2 16  ? 388.201 367.797 284.420 1.00 91.72  ? 16  ILE A CB    1 
ATOM   6783  C  CG1   . ILE C 2 16  ? 387.727 369.106 285.057 1.00 94.95  ? 16  ILE A CG1   1 
ATOM   6784  C  CG2   . ILE C 2 16  ? 388.159 367.948 282.900 1.00 97.85  ? 16  ILE A CG2   1 
ATOM   6785  C  CD1   . ILE C 2 16  ? 388.802 370.148 285.191 1.00 99.53  ? 16  ILE A CD1   1 
ATOM   6786  N  N     . GLY C 2 17  ? 388.390 364.507 284.335 1.00 102.92 ? 17  GLY A N     1 
ATOM   6787  C  CA    . GLY C 2 17  ? 388.513 363.273 283.576 1.00 98.69  ? 17  GLY A CA    1 
ATOM   6788  C  C     . GLY C 2 17  ? 387.314 362.355 283.728 1.00 101.11 ? 17  GLY A C     1 
ATOM   6789  O  O     . GLY C 2 17  ? 386.907 361.697 282.769 1.00 107.75 ? 17  GLY A O     1 
ATOM   6790  N  N     . ASN C 2 18  ? 386.746 362.285 284.936 1.00 103.42 ? 18  ASN A N     1 
ATOM   6791  C  CA    . ASN C 2 18  ? 385.486 361.566 285.132 1.00 102.19 ? 18  ASN A CA    1 
ATOM   6792  C  C     . ASN C 2 18  ? 384.399 362.117 284.227 1.00 103.40 ? 18  ASN A C     1 
ATOM   6793  O  O     . ASN C 2 18  ? 383.727 361.359 283.513 1.00 107.95 ? 18  ASN A O     1 
ATOM   6794  C  CB    . ASN C 2 18  ? 385.024 361.646 286.589 1.00 102.08 ? 18  ASN A CB    1 
ATOM   6795  C  CG    . ASN C 2 18  ? 386.029 361.091 287.567 1.00 111.42 ? 18  ASN A CG    1 
ATOM   6796  O  OD1   . ASN C 2 18  ? 387.161 360.780 287.215 1.00 122.59 ? 18  ASN A OD1   1 
ATOM   6797  N  ND2   . ASN C 2 18  ? 385.622 361.008 288.828 1.00 104.59 ? 18  ASN A ND2   1 
ATOM   6798  N  N     . ALA C 2 19  ? 384.229 363.441 284.227 1.00 101.52 ? 19  ALA A N     1 
ATOM   6799  C  CA    . ALA C 2 19  ? 383.201 364.033 283.371 1.00 99.29  ? 19  ALA A CA    1 
ATOM   6800  C  C     . ALA C 2 19  ? 383.500 363.793 281.892 1.00 99.29  ? 19  ALA A C     1 
ATOM   6801  O  O     . ALA C 2 19  ? 382.594 363.494 281.102 1.00 102.67 ? 19  ALA A O     1 
ATOM   6802  C  CB    . ALA C 2 19  ? 383.074 365.526 283.655 1.00 99.43  ? 19  ALA A CB    1 
ATOM   6803  N  N     . CYS C 2 20  ? 384.772 363.886 281.509 1.00 101.92 ? 20  CYS A N     1 
ATOM   6804  C  CA    . CYS C 2 20  ? 385.159 363.755 280.109 1.00 101.32 ? 20  CYS A CA    1 
ATOM   6805  C  C     . CYS C 2 20  ? 384.935 362.338 279.601 1.00 103.69 ? 20  CYS A C     1 
ATOM   6806  O  O     . CYS C 2 20  ? 384.418 362.140 278.496 1.00 111.58 ? 20  CYS A O     1 
ATOM   6807  C  CB    . CYS C 2 20  ? 386.624 364.153 279.948 1.00 99.66  ? 20  CYS A CB    1 
ATOM   6808  S  SG    . CYS C 2 20  ? 386.910 365.924 280.093 1.00 119.00 ? 20  CYS A SG    1 
ATOM   6809  N  N     . TRP C 2 21  ? 385.328 361.336 280.388 1.00 89.68  ? 21  TRP A N     1 
ATOM   6810  C  CA    . TRP C 2 21  ? 385.137 359.960 279.954 1.00 87.93  ? 21  TRP A CA    1 
ATOM   6811  C  C     . TRP C 2 21  ? 383.673 359.555 280.030 1.00 95.12  ? 21  TRP A C     1 
ATOM   6812  O  O     . TRP C 2 21  ? 383.229 358.724 279.231 1.00 102.92 ? 21  TRP A O     1 
ATOM   6813  C  CB    . TRP C 2 21  ? 386.027 359.025 280.771 1.00 91.94  ? 21  TRP A CB    1 
ATOM   6814  C  CG    . TRP C 2 21  ? 387.465 359.120 280.345 1.00 97.43  ? 21  TRP A CG    1 
ATOM   6815  C  CD1   . TRP C 2 21  ? 388.485 359.713 281.026 1.00 102.76 ? 21  TRP A CD1   1 
ATOM   6816  C  CD2   . TRP C 2 21  ? 388.036 358.617 279.130 1.00 98.04  ? 21  TRP A CD2   1 
ATOM   6817  N  NE1   . TRP C 2 21  ? 389.654 359.612 280.314 1.00 102.67 ? 21  TRP A NE1   1 
ATOM   6818  C  CE2   . TRP C 2 21  ? 389.405 358.943 279.146 1.00 96.66  ? 21  TRP A CE2   1 
ATOM   6819  C  CE3   . TRP C 2 21  ? 387.523 357.920 278.033 1.00 99.72  ? 21  TRP A CE3   1 
ATOM   6820  C  CZ2   . TRP C 2 21  ? 390.265 358.599 278.108 1.00 95.44  ? 21  TRP A CZ2   1 
ATOM   6821  C  CZ3   . TRP C 2 21  ? 388.379 357.585 277.001 1.00 97.86  ? 21  TRP A CZ3   1 
ATOM   6822  C  CH2   . TRP C 2 21  ? 389.734 357.922 277.048 1.00 97.53  ? 21  TRP A CH2   1 
ATOM   6823  N  N     . GLU C 2 22  ? 382.897 360.160 280.937 1.00 97.01  ? 22  GLU A N     1 
ATOM   6824  C  CA    . GLU C 2 22  ? 381.447 359.995 280.888 1.00 92.79  ? 22  GLU A CA    1 
ATOM   6825  C  C     . GLU C 2 22  ? 380.889 360.503 279.562 1.00 92.05  ? 22  GLU A C     1 
ATOM   6826  O  O     . GLU C 2 22  ? 380.083 359.826 278.911 1.00 95.74  ? 22  GLU A O     1 
ATOM   6827  C  CB    . GLU C 2 22  ? 380.808 360.730 282.070 1.00 98.73  ? 22  GLU A CB    1 
ATOM   6828  C  CG    . GLU C 2 22  ? 379.302 360.965 281.961 1.00 103.73 ? 22  GLU A CG    1 
ATOM   6829  C  CD    . GLU C 2 22  ? 378.682 361.359 283.286 1.00 105.93 ? 22  GLU A CD    1 
ATOM   6830  O  OE1   . GLU C 2 22  ? 379.201 362.293 283.932 1.00 101.55 ? 22  GLU A OE1   1 
ATOM   6831  O  OE2   . GLU C 2 22  ? 377.674 360.737 283.682 1.00 108.33 ? 22  GLU A OE2   1 
ATOM   6832  N  N     . LEU C 2 23  ? 381.322 361.695 279.141 1.00 96.62  ? 23  LEU A N     1 
ATOM   6833  C  CA    . LEU C 2 23  ? 380.831 362.255 277.886 1.00 98.92  ? 23  LEU A CA    1 
ATOM   6834  C  C     . LEU C 2 23  ? 381.267 361.415 276.690 1.00 100.73 ? 23  LEU A C     1 
ATOM   6835  O  O     . LEU C 2 23  ? 380.483 361.205 275.759 1.00 107.21 ? 23  LEU A O     1 
ATOM   6836  C  CB    . LEU C 2 23  ? 381.311 363.698 277.731 1.00 100.68 ? 23  LEU A CB    1 
ATOM   6837  C  CG    . LEU C 2 23  ? 380.855 364.475 276.489 1.00 102.89 ? 23  LEU A CG    1 
ATOM   6838  C  CD1   . LEU C 2 23  ? 379.340 364.575 276.405 1.00 105.77 ? 23  LEU A CD1   1 
ATOM   6839  C  CD2   . LEU C 2 23  ? 381.471 365.852 276.499 1.00 108.00 ? 23  LEU A CD2   1 
ATOM   6840  N  N     . TYR C 2 24  ? 382.515 360.940 276.688 1.00 103.25 ? 24  TYR A N     1 
ATOM   6841  C  CA    . TYR C 2 24  ? 382.981 360.101 275.587 1.00 105.02 ? 24  TYR A CA    1 
ATOM   6842  C  C     . TYR C 2 24  ? 382.215 358.786 275.526 1.00 105.18 ? 24  TYR A C     1 
ATOM   6843  O  O     . TYR C 2 24  ? 381.881 358.308 274.435 1.00 110.39 ? 24  TYR A O     1 
ATOM   6844  C  CB    . TYR C 2 24  ? 384.480 359.819 275.713 1.00 107.83 ? 24  TYR A CB    1 
ATOM   6845  C  CG    . TYR C 2 24  ? 385.403 361.024 275.735 1.00 107.79 ? 24  TYR A CG    1 
ATOM   6846  C  CD1   . TYR C 2 24  ? 385.076 362.211 275.092 1.00 106.58 ? 24  TYR A CD1   1 
ATOM   6847  C  CD2   . TYR C 2 24  ? 386.623 360.954 276.382 1.00 106.70 ? 24  TYR A CD2   1 
ATOM   6848  C  CE1   . TYR C 2 24  ? 385.938 363.291 275.114 1.00 106.73 ? 24  TYR A CE1   1 
ATOM   6849  C  CE2   . TYR C 2 24  ? 387.484 362.019 276.410 1.00 109.82 ? 24  TYR A CE2   1 
ATOM   6850  C  CZ    . TYR C 2 24  ? 387.142 363.184 275.777 1.00 111.70 ? 24  TYR A CZ    1 
ATOM   6851  O  OH    . TYR C 2 24  ? 388.022 364.237 275.816 1.00 116.81 ? 24  TYR A OH    1 
ATOM   6852  N  N     . CYS C 2 25  ? 381.944 358.176 276.683 1.00 106.42 ? 25  CYS A N     1 
ATOM   6853  C  CA    . CYS C 2 25  ? 381.162 356.945 276.700 1.00 108.44 ? 25  CYS A CA    1 
ATOM   6854  C  C     . CYS C 2 25  ? 379.755 357.187 276.175 1.00 111.79 ? 25  CYS A C     1 
ATOM   6855  O  O     . CYS C 2 25  ? 379.226 356.378 275.405 1.00 118.63 ? 25  CYS A O     1 
ATOM   6856  C  CB    . CYS C 2 25  ? 381.115 356.375 278.115 1.00 111.49 ? 25  CYS A CB    1 
ATOM   6857  S  SG    . CYS C 2 25  ? 382.605 355.481 278.598 1.00 121.66 ? 25  CYS A SG    1 
ATOM   6858  N  N     . LEU C 2 26  ? 379.137 358.302 276.572 1.00 102.07 ? 26  LEU A N     1 
ATOM   6859  C  CA    . LEU C 2 26  ? 377.805 358.620 276.063 1.00 97.06  ? 26  LEU A CA    1 
ATOM   6860  C  C     . LEU C 2 26  ? 377.828 358.861 274.558 1.00 94.52  ? 26  LEU A C     1 
ATOM   6861  O  O     . LEU C 2 26  ? 376.912 358.438 273.843 1.00 101.66 ? 26  LEU A O     1 
ATOM   6862  C  CB    . LEU C 2 26  ? 377.230 359.843 276.786 1.00 101.02 ? 26  LEU A CB    1 
ATOM   6863  C  CG    . LEU C 2 26  ? 376.296 359.633 277.988 1.00 104.76 ? 26  LEU A CG    1 
ATOM   6864  C  CD1   . LEU C 2 26  ? 375.001 358.932 277.581 1.00 104.56 ? 26  LEU A CD1   1 
ATOM   6865  C  CD2   . LEU C 2 26  ? 376.977 358.875 279.126 1.00 106.57 ? 26  LEU A CD2   1 
ATOM   6866  N  N     . GLU C 2 27  ? 378.863 359.538 274.058 1.00 113.15 ? 27  GLU A N     1 
ATOM   6867  C  CA    . GLU C 2 27  ? 378.917 359.859 272.635 1.00 119.61 ? 27  GLU A CA    1 
ATOM   6868  C  C     . GLU C 2 27  ? 379.146 358.610 271.794 1.00 121.02 ? 27  GLU A C     1 
ATOM   6869  O  O     . GLU C 2 27  ? 378.450 358.387 270.797 1.00 124.25 ? 27  GLU A O     1 
ATOM   6870  C  CB    . GLU C 2 27  ? 380.009 360.896 272.370 1.00 124.12 ? 27  GLU A CB    1 
ATOM   6871  C  CG    . GLU C 2 27  ? 379.557 362.325 272.621 1.00 129.35 ? 27  GLU A CG    1 
ATOM   6872  C  CD    . GLU C 2 27  ? 380.561 363.359 272.165 1.00 132.01 ? 27  GLU A CD    1 
ATOM   6873  O  OE1   . GLU C 2 27  ? 381.750 363.235 272.527 1.00 133.64 ? 27  GLU A OE1   1 
ATOM   6874  O  OE2   . GLU C 2 27  ? 380.164 364.298 271.444 1.00 129.93 ? 27  GLU A OE2   1 
ATOM   6875  N  N     . HIS C 2 28  ? 380.115 357.780 272.179 1.00 115.38 ? 28  HIS A N     1 
ATOM   6876  C  CA    . HIS C 2 28  ? 380.416 356.568 271.428 1.00 112.45 ? 28  HIS A CA    1 
ATOM   6877  C  C     . HIS C 2 28  ? 379.471 355.413 271.733 1.00 112.33 ? 28  HIS A C     1 
ATOM   6878  O  O     . HIS C 2 28  ? 379.574 354.373 271.075 1.00 117.88 ? 28  HIS A O     1 
ATOM   6879  C  CB    . HIS C 2 28  ? 381.856 356.127 271.699 1.00 112.65 ? 28  HIS A CB    1 
ATOM   6880  C  CG    . HIS C 2 28  ? 382.884 357.037 271.106 1.00 113.60 ? 28  HIS A CG    1 
ATOM   6881  N  ND1   . HIS C 2 28  ? 383.826 357.696 271.866 1.00 118.36 ? 28  HIS A ND1   1 
ATOM   6882  C  CD2   . HIS C 2 28  ? 383.121 357.393 269.822 1.00 114.01 ? 28  HIS A CD2   1 
ATOM   6883  C  CE1   . HIS C 2 28  ? 384.596 358.421 271.076 1.00 122.07 ? 28  HIS A CE1   1 
ATOM   6884  N  NE2   . HIS C 2 28  ? 384.190 358.256 269.830 1.00 121.38 ? 28  HIS A NE2   1 
ATOM   6885  N  N     . GLY C 2 29  ? 378.562 355.555 272.697 1.00 105.45 ? 29  GLY A N     1 
ATOM   6886  C  CA    . GLY C 2 29  ? 377.639 354.486 273.012 1.00 106.88 ? 29  GLY A CA    1 
ATOM   6887  C  C     . GLY C 2 29  ? 378.203 353.389 273.885 1.00 102.40 ? 29  GLY A C     1 
ATOM   6888  O  O     . GLY C 2 29  ? 377.589 352.320 273.975 1.00 104.67 ? 29  GLY A O     1 
ATOM   6889  N  N     . ILE C 2 30  ? 379.346 353.612 274.526 1.00 98.05  ? 30  ILE A N     1 
ATOM   6890  C  CA    . ILE C 2 30  ? 379.942 352.614 275.406 1.00 95.51  ? 30  ILE A CA    1 
ATOM   6891  C  C     . ILE C 2 30  ? 379.224 352.659 276.747 1.00 101.82 ? 30  ILE A C     1 
ATOM   6892  O  O     . ILE C 2 30  ? 379.004 353.736 277.313 1.00 114.17 ? 30  ILE A O     1 
ATOM   6893  C  CB    . ILE C 2 30  ? 381.450 352.868 275.568 1.00 102.54 ? 30  ILE A CB    1 
ATOM   6894  C  CG1   . ILE C 2 30  ? 382.197 352.436 274.309 1.00 106.64 ? 30  ILE A CG1   1 
ATOM   6895  C  CG2   . ILE C 2 30  ? 382.028 352.111 276.769 1.00 104.36 ? 30  ILE A CG2   1 
ATOM   6896  C  CD1   . ILE C 2 30  ? 383.495 353.179 274.095 1.00 103.98 ? 30  ILE A CD1   1 
ATOM   6897  N  N     . GLN C 2 31  ? 378.857 351.487 277.258 1.00 102.49 ? 31  GLN A N     1 
ATOM   6898  C  CA    . GLN C 2 31  ? 378.271 351.399 278.581 1.00 106.46 ? 31  GLN A CA    1 
ATOM   6899  C  C     . GLN C 2 31  ? 379.353 351.626 279.637 1.00 107.44 ? 31  GLN A C     1 
ATOM   6900  O  O     . GLN C 2 31  ? 380.543 351.492 279.346 1.00 111.40 ? 31  GLN A O     1 
ATOM   6901  C  CB    . GLN C 2 31  ? 377.615 350.036 278.775 1.00 103.55 ? 31  GLN A CB    1 
ATOM   6902  C  CG    . GLN C 2 31  ? 376.254 349.916 278.115 1.00 108.21 ? 31  GLN A CG    1 
ATOM   6903  C  CD    . GLN C 2 31  ? 375.699 348.509 278.173 1.00 114.95 ? 31  GLN A CD    1 
ATOM   6904  O  OE1   . GLN C 2 31  ? 376.339 347.597 278.695 1.00 111.71 ? 31  GLN A OE1   1 
ATOM   6905  N  NE2   . GLN C 2 31  ? 374.500 348.324 277.632 1.00 118.39 ? 31  GLN A NE2   1 
ATOM   6906  N  N     . PRO C 2 32  ? 378.974 351.977 280.875 1.00 101.19 ? 32  PRO A N     1 
ATOM   6907  C  CA    . PRO C 2 32  ? 380.004 352.146 281.917 1.00 99.39  ? 32  PRO A CA    1 
ATOM   6908  C  C     . PRO C 2 32  ? 380.773 350.872 282.227 1.00 102.36 ? 32  PRO A C     1 
ATOM   6909  O  O     . PRO C 2 32  ? 381.904 350.948 282.721 1.00 105.24 ? 32  PRO A O     1 
ATOM   6910  C  CB    . PRO C 2 32  ? 379.202 352.630 283.134 1.00 105.03 ? 32  PRO A CB    1 
ATOM   6911  C  CG    . PRO C 2 32  ? 377.804 352.241 282.861 1.00 105.61 ? 32  PRO A CG    1 
ATOM   6912  C  CD    . PRO C 2 32  ? 377.637 352.330 281.386 1.00 105.47 ? 32  PRO A CD    1 
ATOM   6913  N  N     . ASP C 2 33  ? 380.194 349.702 281.952 1.00 114.16 ? 33  ASP A N     1 
ATOM   6914  C  CA    . ASP C 2 33  ? 380.909 348.443 282.111 1.00 118.52 ? 33  ASP A CA    1 
ATOM   6915  C  C     . ASP C 2 33  ? 382.041 348.266 281.105 1.00 117.10 ? 33  ASP A C     1 
ATOM   6916  O  O     . ASP C 2 33  ? 382.904 347.410 281.328 1.00 115.63 ? 33  ASP A O     1 
ATOM   6917  C  CB    . ASP C 2 33  ? 379.932 347.273 281.979 1.00 119.92 ? 33  ASP A CB    1 
ATOM   6918  C  CG    . ASP C 2 33  ? 378.940 347.201 283.128 1.00 126.10 ? 33  ASP A CG    1 
ATOM   6919  O  OD1   . ASP C 2 33  ? 379.164 347.857 284.168 1.00 125.27 ? 33  ASP A OD1   1 
ATOM   6920  O  OD2   . ASP C 2 33  ? 377.926 346.486 282.988 1.00 124.87 ? 33  ASP A OD2   1 
ATOM   6921  N  N     . GLY C 2 34  ? 382.058 349.041 280.015 1.00 110.01 ? 34  GLY A N     1 
ATOM   6922  C  CA    . GLY C 2 34  ? 383.071 348.962 278.982 1.00 106.15 ? 34  GLY A CA    1 
ATOM   6923  C  C     . GLY C 2 34  ? 382.601 348.316 277.695 1.00 105.28 ? 34  GLY A C     1 
ATOM   6924  O  O     . GLY C 2 34  ? 383.232 348.525 276.651 1.00 107.89 ? 34  GLY A O     1 
ATOM   6925  N  N     . GLN C 2 35  ? 381.515 347.548 277.732 1.00 105.94 ? 35  GLN A N     1 
ATOM   6926  C  CA    . GLN C 2 35  ? 381.007 346.885 276.542 1.00 107.43 ? 35  GLN A CA    1 
ATOM   6927  C  C     . GLN C 2 35  ? 380.160 347.839 275.710 1.00 105.28 ? 35  GLN A C     1 
ATOM   6928  O  O     . GLN C 2 35  ? 379.477 348.720 276.240 1.00 106.00 ? 35  GLN A O     1 
ATOM   6929  C  CB    . GLN C 2 35  ? 380.168 345.665 276.927 1.00 108.66 ? 35  GLN A CB    1 
ATOM   6930  C  CG    . GLN C 2 35  ? 380.960 344.473 277.475 1.00 106.83 ? 35  GLN A CG    1 
ATOM   6931  C  CD    . GLN C 2 35  ? 381.914 343.848 276.466 1.00 113.97 ? 35  GLN A CD    1 
ATOM   6932  O  OE1   . GLN C 2 35  ? 383.087 343.628 276.765 1.00 117.92 ? 35  GLN A OE1   1 
ATOM   6933  N  NE2   . GLN C 2 35  ? 381.411 343.545 275.272 1.00 110.48 ? 35  GLN A NE2   1 
ATOM   6934  N  N     . MET C 2 36  ? 380.210 347.645 274.390 1.00 112.17 ? 36  MET A N     1 
ATOM   6935  C  CA    . MET C 2 36  ? 379.384 348.388 273.450 1.00 115.88 ? 36  MET A CA    1 
ATOM   6936  C  C     . MET C 2 36  ? 378.158 347.532 273.148 1.00 115.77 ? 36  MET A C     1 
ATOM   6937  O  O     . MET C 2 36  ? 378.316 346.448 272.565 1.00 119.60 ? 36  MET A O     1 
ATOM   6938  C  CB    . MET C 2 36  ? 380.166 348.682 272.168 1.00 116.14 ? 36  MET A CB    1 
ATOM   6939  C  CG    . MET C 2 36  ? 379.436 349.517 271.106 1.00 119.44 ? 36  MET A CG    1 
ATOM   6940  S  SD    . MET C 2 36  ? 379.717 351.281 271.318 1.00 135.45 ? 36  MET A SD    1 
ATOM   6941  C  CE    . MET C 2 36  ? 381.007 351.569 270.113 1.00 120.50 ? 36  MET A CE    1 
ATOM   6942  N  N     . PRO C 2 37  ? 376.930 347.940 273.505 1.00 117.26 ? 37  PRO A N     1 
ATOM   6943  C  CA    . PRO C 2 37  ? 375.787 347.051 273.246 1.00 120.63 ? 37  PRO A CA    1 
ATOM   6944  C  C     . PRO C 2 37  ? 375.424 346.933 271.776 1.00 123.87 ? 37  PRO A C     1 
ATOM   6945  O  O     . PRO C 2 37  ? 374.750 345.965 271.403 1.00 118.29 ? 37  PRO A O     1 
ATOM   6946  C  CB    . PRO C 2 37  ? 374.654 347.696 274.048 1.00 117.95 ? 37  PRO A CB    1 
ATOM   6947  C  CG    . PRO C 2 37  ? 374.966 349.131 274.015 1.00 120.95 ? 37  PRO A CG    1 
ATOM   6948  C  CD    . PRO C 2 37  ? 376.469 349.244 274.024 1.00 119.57 ? 37  PRO A CD    1 
ATOM   6949  N  N     . SER C 2 38  ? 375.841 347.874 270.934 1.00 135.80 ? 38  SER A N     1 
ATOM   6950  C  CA    . SER C 2 38  ? 375.514 347.828 269.514 1.00 136.88 ? 38  SER A CA    1 
ATOM   6951  C  C     . SER C 2 38  ? 376.227 346.664 268.834 1.00 132.41 ? 38  SER A C     1 
ATOM   6952  O  O     . SER C 2 38  ? 377.448 346.677 268.676 1.00 129.29 ? 38  SER A O     1 
ATOM   6953  C  CB    . SER C 2 38  ? 375.891 349.147 268.835 1.00 134.72 ? 38  SER A CB    1 
ATOM   6954  O  OG    . SER C 2 38  ? 375.488 349.157 267.476 1.00 130.61 ? 38  SER A OG    1 
ATOM   6955  N  N     . GLY C 2 43  ? 378.128 352.421 262.362 1.00 173.34 ? 43  GLY A N     1 
ATOM   6956  C  CA    . GLY C 2 43  ? 379.230 352.068 261.486 1.00 174.74 ? 43  GLY A CA    1 
ATOM   6957  C  C     . GLY C 2 43  ? 380.349 353.091 261.521 1.00 176.84 ? 43  GLY A C     1 
ATOM   6958  O  O     . GLY C 2 43  ? 381.515 352.744 261.708 1.00 177.83 ? 43  GLY A O     1 
ATOM   6959  N  N     . GLY C 2 44  ? 379.989 354.363 261.342 1.00 181.82 ? 44  GLY A N     1 
ATOM   6960  C  CA    . GLY C 2 44  ? 380.969 355.433 261.418 1.00 181.15 ? 44  GLY A CA    1 
ATOM   6961  C  C     . GLY C 2 44  ? 381.521 355.670 262.809 1.00 182.41 ? 44  GLY A C     1 
ATOM   6962  O  O     . GLY C 2 44  ? 382.551 356.337 262.948 1.00 181.16 ? 44  GLY A O     1 
ATOM   6963  N  N     . GLY C 2 45  ? 380.857 355.147 263.842 1.00 175.17 ? 45  GLY A N     1 
ATOM   6964  C  CA    . GLY C 2 45  ? 381.314 355.353 265.202 1.00 172.24 ? 45  GLY A CA    1 
ATOM   6965  C  C     . GLY C 2 45  ? 382.525 354.530 265.594 1.00 175.04 ? 45  GLY A C     1 
ATOM   6966  O  O     . GLY C 2 45  ? 383.161 354.848 266.597 1.00 172.90 ? 45  GLY A O     1 
ATOM   6967  N  N     . ASP C 2 46  ? 382.890 353.521 264.789 1.00 165.73 ? 46  ASP A N     1 
ATOM   6968  C  CA    . ASP C 2 46  ? 383.998 352.581 265.143 1.00 160.62 ? 46  ASP A CA    1 
ATOM   6969  C  C     . ASP C 2 46  ? 385.363 353.280 265.229 1.00 156.53 ? 46  ASP A C     1 
ATOM   6970  O  O     . ASP C 2 46  ? 385.949 353.291 266.319 1.00 154.02 ? 46  ASP A O     1 
ATOM   6971  C  CB    . ASP C 2 46  ? 384.065 351.415 264.155 1.00 158.03 ? 46  ASP A CB    1 
ATOM   6972  C  CG    . ASP C 2 46  ? 382.910 350.439 264.298 1.00 158.05 ? 46  ASP A CG    1 
ATOM   6973  O  OD1   . ASP C 2 46  ? 382.217 350.500 265.334 1.00 159.31 ? 46  ASP A OD1   1 
ATOM   6974  O  OD2   . ASP C 2 46  ? 382.709 349.630 263.372 1.00 156.16 ? 46  ASP A OD2   1 
ATOM   6975  N  N     . ASP C 2 47  ? 385.871 353.794 264.109 1.00 142.15 ? 47  ASP A N     1 
ATOM   6976  C  CA    . ASP C 2 47  ? 387.172 354.512 264.123 1.00 144.06 ? 47  ASP A CA    1 
ATOM   6977  C  C     . ASP C 2 47  ? 387.075 355.658 265.131 1.00 145.21 ? 47  ASP A C     1 
ATOM   6978  O  O     . ASP C 2 47  ? 388.003 355.811 265.943 1.00 143.06 ? 47  ASP A O     1 
ATOM   6979  C  CB    . ASP C 2 47  ? 387.546 355.022 262.730 1.00 147.72 ? 47  ASP A CB    1 
ATOM   6980  C  CG    . ASP C 2 47  ? 387.940 353.922 261.757 1.00 151.47 ? 47  ASP A CG    1 
ATOM   6981  O  OD1   . ASP C 2 47  ? 388.201 352.796 262.224 1.00 149.76 ? 47  ASP A OD1   1 
ATOM   6982  O  OD2   . ASP C 2 47  ? 387.998 354.202 260.543 1.00 150.02 ? 47  ASP A OD2   1 
ATOM   6983  N  N     . SER C 2 48  ? 385.989 356.432 265.072 1.00 149.31 ? 48  SER A N     1 
ATOM   6984  C  CA    . SER C 2 48  ? 385.787 357.517 266.064 1.00 152.18 ? 48  SER A CA    1 
ATOM   6985  C  C     . SER C 2 48  ? 386.054 356.949 267.455 1.00 150.99 ? 48  SER A C     1 
ATOM   6986  O  O     . SER C 2 48  ? 386.690 357.642 268.272 1.00 152.54 ? 48  SER A O     1 
ATOM   6987  C  CB    . SER C 2 48  ? 384.400 358.083 265.968 1.00 150.97 ? 48  SER A CB    1 
ATOM   6988  O  OG    . SER C 2 48  ? 383.437 357.097 266.305 1.00 151.85 ? 48  SER A OG    1 
ATOM   6989  N  N     . PHE C 2 49  ? 385.582 355.728 267.701 1.00 137.53 ? 49  PHE A N     1 
ATOM   6990  C  CA    . PHE C 2 49  ? 385.792 355.082 268.989 1.00 133.85 ? 49  PHE A CA    1 
ATOM   6991  C  C     . PHE C 2 49  ? 387.254 354.707 269.196 1.00 133.29 ? 49  PHE A C     1 
ATOM   6992  O  O     . PHE C 2 49  ? 387.769 354.808 270.315 1.00 134.76 ? 49  PHE A O     1 
ATOM   6993  C  CB    . PHE C 2 49  ? 384.881 353.847 269.080 1.00 133.79 ? 49  PHE A CB    1 
ATOM   6994  C  CG    . PHE C 2 49  ? 385.515 352.662 269.724 1.00 137.20 ? 49  PHE A CG    1 
ATOM   6995  C  CD1   . PHE C 2 49  ? 385.592 352.568 271.094 1.00 142.77 ? 49  PHE A CD1   1 
ATOM   6996  C  CD2   . PHE C 2 49  ? 386.028 351.630 268.953 1.00 133.82 ? 49  PHE A CD2   1 
ATOM   6997  C  CE1   . PHE C 2 49  ? 386.165 351.483 271.685 1.00 141.94 ? 49  PHE A CE1   1 
ATOM   6998  C  CE2   . PHE C 2 49  ? 386.613 350.540 269.547 1.00 133.83 ? 49  PHE A CE2   1 
ATOM   6999  C  CZ    . PHE C 2 49  ? 386.682 350.470 270.917 1.00 134.99 ? 49  PHE A CZ    1 
ATOM   7000  N  N     . ASN C 2 50  ? 387.931 354.269 268.134 1.00 126.70 ? 50  ASN A N     1 
ATOM   7001  C  CA    . ASN C 2 50  ? 389.282 353.732 268.276 1.00 126.00 ? 50  ASN A CA    1 
ATOM   7002  C  C     . ASN C 2 50  ? 390.308 354.781 268.702 1.00 124.52 ? 50  ASN A C     1 
ATOM   7003  O  O     . ASN C 2 50  ? 391.383 354.409 269.184 1.00 121.32 ? 50  ASN A O     1 
ATOM   7004  C  CB    . ASN C 2 50  ? 389.721 353.089 266.959 1.00 130.66 ? 50  ASN A CB    1 
ATOM   7005  C  CG    . ASN C 2 50  ? 391.025 352.327 267.086 1.00 130.64 ? 50  ASN A CG    1 
ATOM   7006  O  OD1   . ASN C 2 50  ? 392.098 352.860 266.802 1.00 127.92 ? 50  ASN A OD1   1 
ATOM   7007  N  ND2   . ASN C 2 50  ? 390.940 351.077 267.521 1.00 132.15 ? 50  ASN A ND2   1 
ATOM   7008  N  N     . THR C 2 51  ? 390.008 356.074 268.543 1.00 122.04 ? 51  THR A N     1 
ATOM   7009  C  CA    . THR C 2 51  ? 390.997 357.112 268.827 1.00 121.27 ? 51  THR A CA    1 
ATOM   7010  C  C     . THR C 2 51  ? 391.363 357.150 270.307 1.00 120.42 ? 51  THR A C     1 
ATOM   7011  O  O     . THR C 2 51  ? 392.547 357.128 270.663 1.00 121.00 ? 51  THR A O     1 
ATOM   7012  C  CB    . THR C 2 51  ? 390.463 358.471 268.370 1.00 124.71 ? 51  THR A CB    1 
ATOM   7013  O  OG1   . THR C 2 51  ? 390.349 358.486 266.942 1.00 122.71 ? 51  THR A OG1   1 
ATOM   7014  C  CG2   . THR C 2 51  ? 391.374 359.613 268.822 1.00 125.38 ? 51  THR A CG2   1 
ATOM   7015  N  N     . PHE C 2 52  ? 390.358 357.194 271.183 1.00 107.54 ? 52  PHE A N     1 
ATOM   7016  C  CA    . PHE C 2 52  ? 390.574 357.357 272.616 1.00 104.74 ? 52  PHE A CA    1 
ATOM   7017  C  C     . PHE C 2 52  ? 390.587 356.047 273.392 1.00 103.37 ? 52  PHE A C     1 
ATOM   7018  O  O     . PHE C 2 52  ? 391.075 356.034 274.528 1.00 109.10 ? 52  PHE A O     1 
ATOM   7019  C  CB    . PHE C 2 52  ? 389.493 358.266 273.211 1.00 109.33 ? 52  PHE A CB    1 
ATOM   7020  C  CG    . PHE C 2 52  ? 389.896 359.707 273.288 1.00 107.34 ? 52  PHE A CG    1 
ATOM   7021  C  CD1   . PHE C 2 52  ? 389.665 360.561 272.227 1.00 105.72 ? 52  PHE A CD1   1 
ATOM   7022  C  CD2   . PHE C 2 52  ? 390.514 360.205 274.420 1.00 111.89 ? 52  PHE A CD2   1 
ATOM   7023  C  CE1   . PHE C 2 52  ? 390.037 361.886 272.296 1.00 108.28 ? 52  PHE A CE1   1 
ATOM   7024  C  CE2   . PHE C 2 52  ? 390.889 361.528 274.494 1.00 114.47 ? 52  PHE A CE2   1 
ATOM   7025  C  CZ    . PHE C 2 52  ? 390.650 362.370 273.431 1.00 112.37 ? 52  PHE A CZ    1 
ATOM   7026  N  N     . PHE C 2 53  ? 390.083 354.958 272.814 1.00 92.72  ? 53  PHE A N     1 
ATOM   7027  C  CA    . PHE C 2 53  ? 389.908 353.683 273.491 1.00 95.06  ? 53  PHE A CA    1 
ATOM   7028  C  C     . PHE C 2 53  ? 390.777 352.608 272.853 1.00 103.48 ? 53  PHE A C     1 
ATOM   7029  O  O     . PHE C 2 53  ? 391.105 352.661 271.665 1.00 108.07 ? 53  PHE A O     1 
ATOM   7030  C  CB    . PHE C 2 53  ? 388.445 353.248 273.440 1.00 97.96  ? 53  PHE A CB    1 
ATOM   7031  C  CG    . PHE C 2 53  ? 387.524 354.107 274.253 1.00 103.32 ? 53  PHE A CG    1 
ATOM   7032  C  CD1   . PHE C 2 53  ? 386.982 355.261 273.720 1.00 103.47 ? 53  PHE A CD1   1 
ATOM   7033  C  CD2   . PHE C 2 53  ? 387.187 353.751 275.546 1.00 105.98 ? 53  PHE A CD2   1 
ATOM   7034  C  CE1   . PHE C 2 53  ? 386.130 356.049 274.463 1.00 103.22 ? 53  PHE A CE1   1 
ATOM   7035  C  CE2   . PHE C 2 53  ? 386.334 354.536 276.294 1.00 101.05 ? 53  PHE A CE2   1 
ATOM   7036  C  CZ    . PHE C 2 53  ? 385.804 355.685 275.750 1.00 99.63  ? 53  PHE A CZ    1 
ATOM   7037  N  N     . SER C 2 54  ? 391.128 351.618 273.671 1.00 119.82 ? 54  SER A N     1 
ATOM   7038  C  CA    . SER C 2 54  ? 391.925 350.465 273.278 1.00 117.31 ? 54  SER A CA    1 
ATOM   7039  C  C     . SER C 2 54  ? 391.017 349.243 273.260 1.00 113.55 ? 54  SER A C     1 
ATOM   7040  O  O     . SER C 2 54  ? 390.286 348.992 274.227 1.00 115.27 ? 54  SER A O     1 
ATOM   7041  C  CB    . SER C 2 54  ? 393.092 350.255 274.241 1.00 114.01 ? 54  SER A CB    1 
ATOM   7042  O  OG    . SER C 2 54  ? 394.057 349.377 273.693 1.00 110.85 ? 54  SER A OG    1 
ATOM   7043  N  N     . GLU C 2 55  ? 391.056 348.505 272.155 1.00 129.56 ? 55  GLU A N     1 
ATOM   7044  C  CA    . GLU C 2 55  ? 390.240 347.312 271.987 1.00 129.71 ? 55  GLU A CA    1 
ATOM   7045  C  C     . GLU C 2 55  ? 390.843 346.139 272.745 1.00 128.96 ? 55  GLU A C     1 
ATOM   7046  O  O     . GLU C 2 55  ? 392.067 345.994 272.824 1.00 132.16 ? 55  GLU A O     1 
ATOM   7047  C  CB    . GLU C 2 55  ? 390.121 346.971 270.500 1.00 132.18 ? 55  GLU A CB    1 
ATOM   7048  C  CG    . GLU C 2 55  ? 389.063 345.928 270.138 1.00 128.76 ? 55  GLU A CG    1 
ATOM   7049  C  CD    . GLU C 2 55  ? 387.684 346.525 270.002 1.00 130.31 ? 55  GLU A CD    1 
ATOM   7050  O  OE1   . GLU C 2 55  ? 387.398 347.504 270.714 1.00 133.07 ? 55  GLU A OE1   1 
ATOM   7051  O  OE2   . GLU C 2 55  ? 386.887 346.018 269.186 1.00 127.21 ? 55  GLU A OE2   1 
ATOM   7052  N  N     . THR C 2 56  ? 389.969 345.307 273.309 1.00 128.36 ? 56  THR A N     1 
ATOM   7053  C  CA    . THR C 2 56  ? 390.330 344.024 273.891 1.00 130.98 ? 56  THR A CA    1 
ATOM   7054  C  C     . THR C 2 56  ? 389.551 342.933 273.169 1.00 133.57 ? 56  THR A C     1 
ATOM   7055  O  O     . THR C 2 56  ? 388.421 343.150 272.721 1.00 132.63 ? 56  THR A O     1 
ATOM   7056  C  CB    . THR C 2 56  ? 390.033 343.993 275.398 1.00 130.34 ? 56  THR A CB    1 
ATOM   7057  O  OG1   . THR C 2 56  ? 390.684 345.099 276.032 1.00 134.25 ? 56  THR A OG1   1 
ATOM   7058  C  CG2   . THR C 2 56  ? 390.538 342.702 276.030 1.00 128.32 ? 56  THR A CG2   1 
ATOM   7059  N  N     . GLY C 2 57  ? 390.170 341.756 273.052 1.00 156.92 ? 57  GLY A N     1 
ATOM   7060  C  CA    . GLY C 2 57  ? 389.583 340.667 272.288 1.00 156.45 ? 57  GLY A CA    1 
ATOM   7061  C  C     . GLY C 2 57  ? 388.258 340.167 272.827 1.00 157.37 ? 57  GLY A C     1 
ATOM   7062  O  O     . GLY C 2 57  ? 387.468 339.596 272.069 1.00 157.85 ? 57  GLY A O     1 
ATOM   7063  N  N     . ALA C 2 58  ? 387.993 340.369 274.116 1.00 148.10 ? 58  ALA A N     1 
ATOM   7064  C  CA    . ALA C 2 58  ? 386.725 339.979 274.717 1.00 147.03 ? 58  ALA A CA    1 
ATOM   7065  C  C     . ALA C 2 58  ? 385.582 340.942 274.404 1.00 145.55 ? 58  ALA A C     1 
ATOM   7066  O  O     . ALA C 2 58  ? 384.450 340.674 274.821 1.00 145.20 ? 58  ALA A O     1 
ATOM   7067  C  CB    . ALA C 2 58  ? 386.886 339.860 276.234 1.00 144.24 ? 58  ALA A CB    1 
ATOM   7068  N  N     . GLY C 2 59  ? 385.841 342.047 273.695 1.00 123.09 ? 59  GLY A N     1 
ATOM   7069  C  CA    . GLY C 2 59  ? 384.836 343.042 273.386 1.00 118.68 ? 59  GLY A CA    1 
ATOM   7070  C  C     . GLY C 2 59  ? 384.819 344.234 274.318 1.00 121.56 ? 59  GLY A C     1 
ATOM   7071  O  O     . GLY C 2 59  ? 384.201 345.251 273.980 1.00 119.07 ? 59  GLY A O     1 
ATOM   7072  N  N     . LYS C 2 60  ? 385.468 344.143 275.475 1.00 122.47 ? 60  LYS A N     1 
ATOM   7073  C  CA    . LYS C 2 60  ? 385.582 345.293 276.359 1.00 118.62 ? 60  LYS A CA    1 
ATOM   7074  C  C     . LYS C 2 60  ? 386.537 346.320 275.763 1.00 115.53 ? 60  LYS A C     1 
ATOM   7075  O  O     . LYS C 2 60  ? 387.480 345.978 275.046 1.00 122.56 ? 60  LYS A O     1 
ATOM   7076  C  CB    . LYS C 2 60  ? 386.072 344.857 277.740 1.00 119.78 ? 60  LYS A CB    1 
ATOM   7077  C  CG    . LYS C 2 60  ? 385.869 345.904 278.830 1.00 118.05 ? 60  LYS A CG    1 
ATOM   7078  C  CD    . LYS C 2 60  ? 386.386 345.440 280.193 1.00 119.40 ? 60  LYS A CD    1 
ATOM   7079  C  CE    . LYS C 2 60  ? 385.532 344.342 280.829 1.00 123.79 ? 60  LYS A CE    1 
ATOM   7080  N  NZ    . LYS C 2 60  ? 384.101 344.720 281.009 1.00 123.72 ? 60  LYS A NZ    1 
ATOM   7081  N  N     . HIS C 2 61  ? 386.273 347.590 276.066 1.00 107.79 ? 61  HIS A N     1 
ATOM   7082  C  CA    . HIS C 2 61  ? 387.068 348.716 275.592 1.00 109.61 ? 61  HIS A CA    1 
ATOM   7083  C  C     . HIS C 2 61  ? 387.646 349.451 276.790 1.00 111.53 ? 61  HIS A C     1 
ATOM   7084  O  O     . HIS C 2 61  ? 386.905 349.814 277.710 1.00 110.99 ? 61  HIS A O     1 
ATOM   7085  C  CB    . HIS C 2 61  ? 386.217 349.666 274.758 1.00 104.46 ? 61  HIS A CB    1 
ATOM   7086  C  CG    . HIS C 2 61  ? 385.299 348.971 273.803 1.00 106.73 ? 61  HIS A CG    1 
ATOM   7087  N  ND1   . HIS C 2 61  ? 385.749 348.105 272.830 1.00 108.84 ? 61  HIS A ND1   1 
ATOM   7088  C  CD2   . HIS C 2 61  ? 383.953 349.021 273.668 1.00 114.49 ? 61  HIS A CD2   1 
ATOM   7089  C  CE1   . HIS C 2 61  ? 384.719 347.650 272.138 1.00 112.46 ? 61  HIS A CE1   1 
ATOM   7090  N  NE2   . HIS C 2 61  ? 383.618 348.190 272.627 1.00 115.78 ? 61  HIS A NE2   1 
ATOM   7091  N  N     . VAL C 2 62  ? 388.950 349.683 276.766 1.00 99.02  ? 62  VAL A N     1 
ATOM   7092  C  CA    . VAL C 2 62  ? 389.687 350.271 277.885 1.00 92.19  ? 62  VAL A CA    1 
ATOM   7093  C  C     . VAL C 2 62  ? 390.028 351.712 277.518 1.00 91.08  ? 62  VAL A C     1 
ATOM   7094  O  O     . VAL C 2 62  ? 390.525 351.947 276.414 1.00 98.36  ? 62  VAL A O     1 
ATOM   7095  C  CB    . VAL C 2 62  ? 390.971 349.479 278.200 1.00 94.56  ? 62  VAL A CB    1 
ATOM   7096  C  CG1   . VAL C 2 62  ? 391.742 350.151 279.333 1.00 101.73 ? 62  VAL A CG1   1 
ATOM   7097  C  CG2   . VAL C 2 62  ? 390.632 348.029 278.552 1.00 95.65  ? 62  VAL A CG2   1 
ATOM   7098  N  N     . PRO C 2 63  ? 389.780 352.704 278.382 1.00 96.66  ? 63  PRO A N     1 
ATOM   7099  C  CA    . PRO C 2 63  ? 390.269 354.054 278.075 1.00 93.01  ? 63  PRO A CA    1 
ATOM   7100  C  C     . PRO C 2 63  ? 391.787 354.112 278.006 1.00 98.67  ? 63  PRO A C     1 
ATOM   7101  O  O     . PRO C 2 63  ? 392.492 353.400 278.724 1.00 100.94 ? 63  PRO A O     1 
ATOM   7102  C  CB    . PRO C 2 63  ? 389.737 354.896 279.238 1.00 92.12  ? 63  PRO A CB    1 
ATOM   7103  C  CG    . PRO C 2 63  ? 388.553 354.193 279.683 1.00 97.13  ? 63  PRO A CG    1 
ATOM   7104  C  CD    . PRO C 2 63  ? 388.891 352.744 279.557 1.00 106.85 ? 63  PRO A CD    1 
ATOM   7105  N  N     . ARG C 2 64  ? 392.285 354.982 277.126 1.00 105.66 ? 64  ARG A N     1 
ATOM   7106  C  CA    . ARG C 2 64  ? 393.712 355.305 277.060 1.00 103.42 ? 64  ARG A CA    1 
ATOM   7107  C  C     . ARG C 2 64  ? 394.004 356.444 278.036 1.00 102.71 ? 64  ARG A C     1 
ATOM   7108  O  O     . ARG C 2 64  ? 394.445 357.533 277.664 1.00 110.60 ? 64  ARG A O     1 
ATOM   7109  C  CB    . ARG C 2 64  ? 394.110 355.685 275.641 1.00 101.30 ? 64  ARG A CB    1 
ATOM   7110  C  CG    . ARG C 2 64  ? 394.075 354.549 274.644 1.00 103.50 ? 64  ARG A CG    1 
ATOM   7111  C  CD    . ARG C 2 64  ? 394.951 354.859 273.444 1.00 101.08 ? 64  ARG A CD    1 
ATOM   7112  N  NE    . ARG C 2 64  ? 394.873 353.821 272.422 1.00 98.55  ? 64  ARG A NE    1 
ATOM   7113  C  CZ    . ARG C 2 64  ? 393.932 353.728 271.489 1.00 106.95 ? 64  ARG A CZ    1 
ATOM   7114  N  NH1   . ARG C 2 64  ? 392.924 354.587 271.417 1.00 114.57 ? 64  ARG A NH1   1 
ATOM   7115  N  NH2   . ARG C 2 64  ? 394.005 352.748 270.595 1.00 107.31 ? 64  ARG A NH2   1 
ATOM   7116  N  N     . ALA C 2 65  ? 393.757 356.156 279.313 1.00 99.28  ? 65  ALA A N     1 
ATOM   7117  C  CA    . ALA C 2 65  ? 393.775 357.146 280.379 1.00 102.62 ? 65  ALA A CA    1 
ATOM   7118  C  C     . ALA C 2 65  ? 394.770 356.734 281.448 1.00 106.05 ? 65  ALA A C     1 
ATOM   7119  O  O     . ALA C 2 65  ? 394.946 355.546 281.732 1.00 120.04 ? 65  ALA A O     1 
ATOM   7120  C  CB    . ALA C 2 65  ? 392.393 357.310 281.014 1.00 108.41 ? 65  ALA A CB    1 
ATOM   7121  N  N     . VAL C 2 66  ? 395.424 357.736 282.029 1.00 85.93  ? 66  VAL A N     1 
ATOM   7122  C  CA    . VAL C 2 66  ? 396.285 357.567 283.193 1.00 87.66  ? 66  VAL A CA    1 
ATOM   7123  C  C     . VAL C 2 66  ? 395.830 358.580 284.230 1.00 88.50  ? 66  VAL A C     1 
ATOM   7124  O  O     . VAL C 2 66  ? 395.966 359.791 284.017 1.00 94.02  ? 66  VAL A O     1 
ATOM   7125  C  CB    . VAL C 2 66  ? 397.772 357.761 282.852 1.00 89.17  ? 66  VAL A CB    1 
ATOM   7126  C  CG1   . VAL C 2 66  ? 398.654 357.375 284.043 1.00 90.79  ? 66  VAL A CG1   1 
ATOM   7127  C  CG2   . VAL C 2 66  ? 398.143 356.953 281.611 1.00 90.15  ? 66  VAL A CG2   1 
ATOM   7128  N  N     . PHE C 2 67  ? 395.291 358.087 285.341 1.00 94.34  ? 67  PHE A N     1 
ATOM   7129  C  CA    . PHE C 2 67  ? 394.821 358.918 286.442 1.00 94.78  ? 67  PHE A CA    1 
ATOM   7130  C  C     . PHE C 2 67  ? 395.864 358.876 287.548 1.00 102.59 ? 67  PHE A C     1 
ATOM   7131  O  O     . PHE C 2 67  ? 396.195 357.795 288.048 1.00 111.47 ? 67  PHE A O     1 
ATOM   7132  C  CB    . PHE C 2 67  ? 393.471 358.425 286.956 1.00 98.04  ? 67  PHE A CB    1 
ATOM   7133  C  CG    . PHE C 2 67  ? 392.303 358.911 286.152 1.00 94.82  ? 67  PHE A CG    1 
ATOM   7134  C  CD1   . PHE C 2 67  ? 392.141 358.523 284.835 1.00 97.38  ? 67  PHE A CD1   1 
ATOM   7135  C  CD2   . PHE C 2 67  ? 391.363 359.754 286.715 1.00 99.47  ? 67  PHE A CD2   1 
ATOM   7136  C  CE1   . PHE C 2 67  ? 391.066 358.969 284.096 1.00 99.23  ? 67  PHE A CE1   1 
ATOM   7137  C  CE2   . PHE C 2 67  ? 390.287 360.201 285.980 1.00 104.40 ? 67  PHE A CE2   1 
ATOM   7138  C  CZ    . PHE C 2 67  ? 390.139 359.808 284.669 1.00 99.48  ? 67  PHE A CZ    1 
ATOM   7139  N  N     . VAL C 2 68  ? 396.374 360.047 287.924 1.00 98.65  ? 68  VAL A N     1 
ATOM   7140  C  CA    . VAL C 2 68  ? 397.463 360.178 288.885 1.00 97.92  ? 68  VAL A CA    1 
ATOM   7141  C  C     . VAL C 2 68  ? 397.050 361.176 289.953 1.00 97.43  ? 68  VAL A C     1 
ATOM   7142  O  O     . VAL C 2 68  ? 396.553 362.262 289.638 1.00 102.88 ? 68  VAL A O     1 
ATOM   7143  C  CB    . VAL C 2 68  ? 398.772 360.629 288.208 1.00 94.97  ? 68  VAL A CB    1 
ATOM   7144  C  CG1   . VAL C 2 68  ? 399.931 360.593 289.209 1.00 101.26 ? 68  VAL A CG1   1 
ATOM   7145  C  CG2   . VAL C 2 68  ? 399.064 359.759 286.987 1.00 98.60  ? 68  VAL A CG2   1 
ATOM   7146  N  N     . ASP C 2 69  ? 397.253 360.804 291.212 1.00 106.82 ? 69  ASP A N     1 
ATOM   7147  C  CA    . ASP C 2 69  ? 397.081 361.720 292.326 1.00 113.03 ? 69  ASP A CA    1 
ATOM   7148  C  C     . ASP C 2 69  ? 397.898 361.194 293.492 1.00 116.59 ? 69  ASP A C     1 
ATOM   7149  O  O     . ASP C 2 69  ? 397.924 359.988 293.741 1.00 121.99 ? 69  ASP A O     1 
ATOM   7150  C  CB    . ASP C 2 69  ? 395.610 361.866 292.725 1.00 118.69 ? 69  ASP A CB    1 
ATOM   7151  C  CG    . ASP C 2 69  ? 395.336 363.160 293.462 1.00 119.23 ? 69  ASP A CG    1 
ATOM   7152  O  OD1   . ASP C 2 69  ? 396.233 363.629 294.193 1.00 120.53 ? 69  ASP A OD1   1 
ATOM   7153  O  OD2   . ASP C 2 69  ? 394.226 363.709 293.311 1.00 118.81 ? 69  ASP A OD2   1 
ATOM   7154  N  N     . LEU C 2 70  ? 398.560 362.103 294.198 1.00 110.49 ? 70  LEU A N     1 
ATOM   7155  C  CA    . LEU C 2 70  ? 399.415 361.718 295.309 1.00 109.46 ? 70  LEU A CA    1 
ATOM   7156  C  C     . LEU C 2 70  ? 398.630 361.383 296.571 1.00 114.62 ? 70  LEU A C     1 
ATOM   7157  O  O     . LEU C 2 70  ? 399.211 360.807 297.496 1.00 122.69 ? 70  LEU A O     1 
ATOM   7158  C  CB    . LEU C 2 70  ? 400.428 362.831 295.592 1.00 114.41 ? 70  LEU A CB    1 
ATOM   7159  C  CG    . LEU C 2 70  ? 401.221 363.344 294.379 1.00 112.59 ? 70  LEU A CG    1 
ATOM   7160  C  CD1   . LEU C 2 70  ? 402.134 364.479 294.790 1.00 114.53 ? 70  LEU A CD1   1 
ATOM   7161  C  CD2   . LEU C 2 70  ? 402.006 362.225 293.705 1.00 112.46 ? 70  LEU A CD2   1 
ATOM   7162  N  N     . GLU C 2 71  ? 397.328 361.739 296.633 1.00 132.16 ? 71  GLU A N     1 
ATOM   7163  C  CA    . GLU C 2 71  ? 396.388 361.277 297.644 1.00 131.87 ? 71  GLU A CA    1 
ATOM   7164  C  C     . GLU C 2 71  ? 395.448 360.234 297.031 1.00 130.96 ? 71  GLU A C     1 
ATOM   7165  O  O     . GLU C 2 71  ? 395.158 360.309 295.833 1.00 134.58 ? 71  GLU A O     1 
ATOM   7166  C  CB    . GLU C 2 71  ? 395.568 362.443 298.215 1.00 134.28 ? 71  GLU A CB    1 
ATOM   7167  C  CG    . GLU C 2 71  ? 394.333 362.845 297.404 1.00 138.96 ? 71  GLU A CG    1 
ATOM   7168  C  CD    . GLU C 2 71  ? 393.820 364.221 297.773 1.00 141.84 ? 71  GLU A CD    1 
ATOM   7169  O  OE1   . GLU C 2 71  ? 393.305 364.382 298.899 1.00 138.63 ? 71  GLU A OE1   1 
ATOM   7170  O  OE2   . GLU C 2 71  ? 393.932 365.143 296.938 1.00 142.93 ? 71  GLU A OE2   1 
ATOM   7171  N  N     . PRO C 2 72  ? 394.938 359.269 297.801 1.00 108.33 ? 72  PRO A N     1 
ATOM   7172  C  CA    . PRO C 2 72  ? 394.113 358.209 297.207 1.00 112.60 ? 72  PRO A CA    1 
ATOM   7173  C  C     . PRO C 2 72  ? 392.609 358.444 297.226 1.00 113.95 ? 72  PRO A C     1 
ATOM   7174  O  O     . PRO C 2 72  ? 391.885 357.612 296.670 1.00 120.85 ? 72  PRO A O     1 
ATOM   7175  C  CB    . PRO C 2 72  ? 394.468 357.011 298.091 1.00 112.63 ? 72  PRO A CB    1 
ATOM   7176  C  CG    . PRO C 2 72  ? 394.606 357.609 299.440 1.00 110.03 ? 72  PRO A CG    1 
ATOM   7177  C  CD    . PRO C 2 72  ? 395.122 359.020 299.246 1.00 106.92 ? 72  PRO A CD    1 
ATOM   7178  N  N     . THR C 2 73  ? 392.112 359.521 297.843 1.00 110.54 ? 73  THR A N     1 
ATOM   7179  C  CA    . THR C 2 73  ? 390.669 359.622 298.088 1.00 115.59 ? 73  THR A CA    1 
ATOM   7180  C  C     . THR C 2 73  ? 389.881 359.795 296.791 1.00 114.31 ? 73  THR A C     1 
ATOM   7181  O  O     . THR C 2 73  ? 388.872 359.115 296.573 1.00 121.09 ? 73  THR A O     1 
ATOM   7182  C  CB    . THR C 2 73  ? 390.329 360.755 299.078 1.00 121.25 ? 73  THR A CB    1 
ATOM   7183  O  OG1   . THR C 2 73  ? 388.917 361.003 299.040 1.00 125.32 ? 73  THR A OG1   1 
ATOM   7184  C  CG2   . THR C 2 73  ? 391.057 362.086 298.801 1.00 118.90 ? 73  THR A CG2   1 
ATOM   7185  N  N     . VAL C 2 74  ? 390.326 360.688 295.911 1.00 108.92 ? 74  VAL A N     1 
ATOM   7186  C  CA    . VAL C 2 74  ? 389.559 360.963 294.699 1.00 115.96 ? 74  VAL A CA    1 
ATOM   7187  C  C     . VAL C 2 74  ? 389.648 359.788 293.725 1.00 118.62 ? 74  VAL A C     1 
ATOM   7188  O  O     . VAL C 2 74  ? 388.661 359.426 293.068 1.00 120.53 ? 74  VAL A O     1 
ATOM   7189  C  CB    . VAL C 2 74  ? 390.022 362.296 294.075 1.00 114.98 ? 74  VAL A CB    1 
ATOM   7190  C  CG1   . VAL C 2 74  ? 391.488 362.249 293.602 1.00 120.18 ? 74  VAL A CG1   1 
ATOM   7191  C  CG2   . VAL C 2 74  ? 389.080 362.723 292.959 1.00 113.59 ? 74  VAL A CG2   1 
ATOM   7192  N  N     . ILE C 2 75  ? 390.822 359.167 293.617 1.00 115.21 ? 75  ILE A N     1 
ATOM   7193  C  CA    . ILE C 2 75  ? 390.944 358.008 292.741 1.00 110.62 ? 75  ILE A CA    1 
ATOM   7194  C  C     . ILE C 2 75  ? 390.171 356.827 293.315 1.00 115.25 ? 75  ILE A C     1 
ATOM   7195  O  O     . ILE C 2 75  ? 389.676 355.983 292.564 1.00 121.88 ? 75  ILE A O     1 
ATOM   7196  C  CB    . ILE C 2 75  ? 392.431 357.687 292.492 1.00 113.93 ? 75  ILE A CB    1 
ATOM   7197  C  CG1   . ILE C 2 75  ? 393.009 358.705 291.504 1.00 113.69 ? 75  ILE A CG1   1 
ATOM   7198  C  CG2   . ILE C 2 75  ? 392.621 356.274 291.930 1.00 113.93 ? 75  ILE A CG2   1 
ATOM   7199  C  CD1   . ILE C 2 75  ? 394.505 358.859 291.567 1.00 116.95 ? 75  ILE A CD1   1 
ATOM   7200  N  N     . ASP C 2 76  ? 390.035 356.744 294.640 1.00 121.16 ? 76  ASP A N     1 
ATOM   7201  C  CA    . ASP C 2 76  ? 389.157 355.730 295.213 1.00 119.78 ? 76  ASP A CA    1 
ATOM   7202  C  C     . ASP C 2 76  ? 387.695 356.051 294.938 1.00 119.73 ? 76  ASP A C     1 
ATOM   7203  O  O     . ASP C 2 76  ? 386.876 355.137 294.795 1.00 126.60 ? 76  ASP A O     1 
ATOM   7204  C  CB    . ASP C 2 76  ? 389.407 355.604 296.715 1.00 125.58 ? 76  ASP A CB    1 
ATOM   7205  C  CG    . ASP C 2 76  ? 390.685 354.838 297.041 1.00 129.28 ? 76  ASP A CG    1 
ATOM   7206  O  OD1   . ASP C 2 76  ? 391.348 354.316 296.119 1.00 127.76 ? 76  ASP A OD1   1 
ATOM   7207  O  OD2   . ASP C 2 76  ? 391.031 354.760 298.238 1.00 129.28 ? 76  ASP A OD2   1 
ATOM   7208  N  N     . GLU C 2 77  ? 387.352 357.339 294.855 1.00 114.42 ? 77  GLU A N     1 
ATOM   7209  C  CA    . GLU C 2 77  ? 386.026 357.717 294.367 1.00 112.53 ? 77  GLU A CA    1 
ATOM   7210  C  C     . GLU C 2 77  ? 385.805 357.199 292.952 1.00 109.99 ? 77  GLU A C     1 
ATOM   7211  O  O     . GLU C 2 77  ? 384.719 356.709 292.623 1.00 106.26 ? 77  GLU A O     1 
ATOM   7212  C  CB    . GLU C 2 77  ? 385.843 359.238 294.397 1.00 114.88 ? 77  GLU A CB    1 
ATOM   7213  C  CG    . GLU C 2 77  ? 384.764 359.713 295.349 1.00 114.64 ? 77  GLU A CG    1 
ATOM   7214  C  CD    . GLU C 2 77  ? 384.581 361.217 295.310 1.00 119.80 ? 77  GLU A CD    1 
ATOM   7215  O  OE1   . GLU C 2 77  ? 385.597 361.941 295.278 1.00 117.38 ? 77  GLU A OE1   1 
ATOM   7216  O  OE2   . GLU C 2 77  ? 383.419 361.676 295.308 1.00 121.74 ? 77  GLU A OE2   1 
ATOM   7217  N  N     . VAL C 2 78  ? 386.828 357.307 292.103 1.00 109.36 ? 78  VAL A N     1 
ATOM   7218  C  CA    . VAL C 2 78  ? 386.740 356.745 290.754 1.00 105.50 ? 78  VAL A CA    1 
ATOM   7219  C  C     . VAL C 2 78  ? 386.574 355.230 290.816 1.00 107.33 ? 78  VAL A C     1 
ATOM   7220  O  O     . VAL C 2 78  ? 385.731 354.653 290.118 1.00 113.43 ? 78  VAL A O     1 
ATOM   7221  C  CB    . VAL C 2 78  ? 387.974 357.137 289.917 1.00 112.43 ? 78  VAL A CB    1 
ATOM   7222  C  CG1   . VAL C 2 78  ? 387.945 356.437 288.560 1.00 109.93 ? 78  VAL A CG1   1 
ATOM   7223  C  CG2   . VAL C 2 78  ? 388.042 358.647 289.711 1.00 114.99 ? 78  VAL A CG2   1 
ATOM   7224  N  N     . ARG C 2 79  ? 387.371 354.564 291.653 1.00 109.11 ? 79  ARG A N     1 
ATOM   7225  C  CA    . ARG C 2 79  ? 387.338 353.110 291.772 1.00 107.49 ? 79  ARG A CA    1 
ATOM   7226  C  C     . ARG C 2 79  ? 386.054 352.587 292.405 1.00 111.75 ? 79  ARG A C     1 
ATOM   7227  O  O     . ARG C 2 79  ? 385.802 351.381 292.325 1.00 110.28 ? 79  ARG A O     1 
ATOM   7228  C  CB    . ARG C 2 79  ? 388.527 352.623 292.602 1.00 108.81 ? 79  ARG A CB    1 
ATOM   7229  C  CG    . ARG C 2 79  ? 389.882 352.755 291.926 1.00 106.77 ? 79  ARG A CG    1 
ATOM   7230  C  CD    . ARG C 2 79  ? 391.008 352.470 292.910 1.00 108.17 ? 79  ARG A CD    1 
ATOM   7231  N  NE    . ARG C 2 79  ? 392.328 352.679 292.320 1.00 110.39 ? 79  ARG A NE    1 
ATOM   7232  C  CZ    . ARG C 2 79  ? 393.442 352.961 292.989 1.00 115.91 ? 79  ARG A CZ    1 
ATOM   7233  N  NH1   . ARG C 2 79  ? 393.464 353.064 294.311 1.00 112.98 ? 79  ARG A NH1   1 
ATOM   7234  N  NH2   . ARG C 2 79  ? 394.572 353.143 292.313 1.00 116.70 ? 79  ARG A NH2   1 
ATOM   7235  N  N     . THR C 2 80  ? 385.272 353.447 293.064 1.00 119.85 ? 80  THR A N     1 
ATOM   7236  C  CA    . THR C 2 80  ? 383.960 353.088 293.589 1.00 113.00 ? 80  THR A CA    1 
ATOM   7237  C  C     . THR C 2 80  ? 382.803 353.582 292.729 1.00 110.09 ? 80  THR A C     1 
ATOM   7238  O  O     . THR C 2 80  ? 381.673 353.124 292.928 1.00 108.97 ? 80  THR A O     1 
ATOM   7239  C  CB    . THR C 2 80  ? 383.788 353.645 295.009 1.00 114.09 ? 80  THR A CB    1 
ATOM   7240  O  OG1   . THR C 2 80  ? 384.107 355.042 295.023 1.00 121.11 ? 80  THR A OG1   1 
ATOM   7241  C  CG2   . THR C 2 80  ? 384.694 352.909 295.984 1.00 110.86 ? 80  THR A CG2   1 
ATOM   7242  N  N     . GLY C 2 81  ? 383.045 354.485 291.785 1.00 110.61 ? 81  GLY A N     1 
ATOM   7243  C  CA    . GLY C 2 81  ? 381.975 355.035 290.985 1.00 111.23 ? 81  GLY A CA    1 
ATOM   7244  C  C     . GLY C 2 81  ? 381.443 354.037 289.972 1.00 112.32 ? 81  GLY A C     1 
ATOM   7245  O  O     . GLY C 2 81  ? 381.829 352.868 289.917 1.00 112.86 ? 81  GLY A O     1 
ATOM   7246  N  N     . THR C 2 82  ? 380.516 354.531 289.148 1.00 110.58 ? 82  THR A N     1 
ATOM   7247  C  CA    . THR C 2 82  ? 379.887 353.685 288.139 1.00 110.09 ? 82  THR A CA    1 
ATOM   7248  C  C     . THR C 2 82  ? 380.876 353.234 287.071 1.00 111.06 ? 82  THR A C     1 
ATOM   7249  O  O     . THR C 2 82  ? 380.706 352.155 286.493 1.00 112.99 ? 82  THR A O     1 
ATOM   7250  C  CB    . THR C 2 82  ? 378.723 354.428 287.484 1.00 106.81 ? 82  THR A CB    1 
ATOM   7251  O  OG1   . THR C 2 82  ? 379.136 355.755 287.137 1.00 108.54 ? 82  THR A OG1   1 
ATOM   7252  C  CG2   . THR C 2 82  ? 377.534 354.502 288.428 1.00 107.26 ? 82  THR A CG2   1 
ATOM   7253  N  N     . TYR C 2 83  ? 381.910 354.036 286.797 1.00 105.39 ? 83  TYR A N     1 
ATOM   7254  C  CA    . TYR C 2 83  ? 382.904 353.734 285.773 1.00 102.89 ? 83  TYR A CA    1 
ATOM   7255  C  C     . TYR C 2 83  ? 384.112 352.983 286.328 1.00 101.92 ? 83  TYR A C     1 
ATOM   7256  O  O     . TYR C 2 83  ? 385.220 353.118 285.793 1.00 110.93 ? 83  TYR A O     1 
ATOM   7257  C  CB    . TYR C 2 83  ? 383.346 355.029 285.087 1.00 102.53 ? 83  TYR A CB    1 
ATOM   7258  C  CG    . TYR C 2 83  ? 382.233 355.739 284.355 1.00 98.58  ? 83  TYR A CG    1 
ATOM   7259  C  CD1   . TYR C 2 83  ? 381.816 355.307 283.105 1.00 101.72 ? 83  TYR A CD1   1 
ATOM   7260  C  CD2   . TYR C 2 83  ? 381.602 356.843 284.909 1.00 100.31 ? 83  TYR A CD2   1 
ATOM   7261  C  CE1   . TYR C 2 83  ? 380.801 355.950 282.429 1.00 106.33 ? 83  TYR A CE1   1 
ATOM   7262  C  CE2   . TYR C 2 83  ? 380.585 357.493 284.241 1.00 107.99 ? 83  TYR A CE2   1 
ATOM   7263  C  CZ    . TYR C 2 83  ? 380.189 357.042 283.001 1.00 109.49 ? 83  TYR A CZ    1 
ATOM   7264  O  OH    . TYR C 2 83  ? 379.177 357.685 282.328 1.00 108.46 ? 83  TYR A OH    1 
ATOM   7265  N  N     . ARG C 2 84  ? 383.932 352.191 287.387 1.00 101.90 ? 84  ARG A N     1 
ATOM   7266  C  CA    . ARG C 2 84  ? 385.066 351.456 287.942 1.00 109.46 ? 84  ARG A CA    1 
ATOM   7267  C  C     . ARG C 2 84  ? 385.513 350.359 286.983 1.00 110.10 ? 84  ARG A C     1 
ATOM   7268  O  O     . ARG C 2 84  ? 386.716 350.139 286.805 1.00 115.87 ? 84  ARG A O     1 
ATOM   7269  C  CB    . ARG C 2 84  ? 384.706 350.920 289.347 1.00 114.14 ? 84  ARG A CB    1 
ATOM   7270  C  CG    . ARG C 2 84  ? 385.354 349.582 289.905 1.00 116.38 ? 84  ARG A CG    1 
ATOM   7271  C  CD    . ARG C 2 84  ? 384.470 348.799 290.896 1.00 116.24 ? 84  ARG A CD    1 
ATOM   7272  N  NE    . ARG C 2 84  ? 383.130 348.459 290.411 1.00 117.87 ? 84  ARG A NE    1 
ATOM   7273  C  CZ    . ARG C 2 84  ? 382.001 349.106 290.693 1.00 116.95 ? 84  ARG A CZ    1 
ATOM   7274  N  NH1   . ARG C 2 84  ? 381.980 350.199 291.444 1.00 116.76 ? 84  ARG A NH1   1 
ATOM   7275  N  NH2   . ARG C 2 84  ? 380.855 348.647 290.198 1.00 112.95 ? 84  ARG A NH2   1 
ATOM   7276  N  N     . GLN C 2 85  ? 384.566 349.658 286.360 1.00 105.63 ? 85  GLN A N     1 
ATOM   7277  C  CA    . GLN C 2 85  ? 384.932 348.606 285.420 1.00 106.31 ? 85  GLN A CA    1 
ATOM   7278  C  C     . GLN C 2 85  ? 385.575 349.161 284.156 1.00 107.97 ? 85  GLN A C     1 
ATOM   7279  O  O     . GLN C 2 85  ? 386.295 348.427 283.471 1.00 110.26 ? 85  GLN A O     1 
ATOM   7280  C  CB    . GLN C 2 85  ? 383.707 347.776 285.032 1.00 108.51 ? 85  GLN A CB    1 
ATOM   7281  C  CG    . GLN C 2 85  ? 382.866 347.268 286.197 1.00 109.39 ? 85  GLN A CG    1 
ATOM   7282  C  CD    . GLN C 2 85  ? 381.649 348.136 286.473 1.00 116.24 ? 85  GLN A CD    1 
ATOM   7283  O  OE1   . GLN C 2 85  ? 381.647 349.336 286.197 1.00 117.21 ? 85  GLN A OE1   1 
ATOM   7284  N  NE2   . GLN C 2 85  ? 380.599 347.525 287.008 1.00 113.75 ? 85  GLN A NE2   1 
ATOM   7285  N  N     . LEU C 2 86  ? 385.325 350.431 283.829 1.00 104.04 ? 86  LEU A N     1 
ATOM   7286  C  CA    . LEU C 2 86  ? 385.789 350.985 282.563 1.00 100.58 ? 86  LEU A CA    1 
ATOM   7287  C  C     . LEU C 2 86  ? 387.309 351.083 282.520 1.00 102.92 ? 86  LEU A C     1 
ATOM   7288  O  O     . LEU C 2 86  ? 387.940 350.663 281.544 1.00 106.43 ? 86  LEU A O     1 
ATOM   7289  C  CB    . LEU C 2 86  ? 385.154 352.359 282.348 1.00 103.88 ? 86  LEU A CB    1 
ATOM   7290  C  CG    . LEU C 2 86  ? 385.325 353.015 280.977 1.00 105.45 ? 86  LEU A CG    1 
ATOM   7291  C  CD1   . LEU C 2 86  ? 384.530 352.280 279.910 1.00 108.31 ? 86  LEU A CD1   1 
ATOM   7292  C  CD2   . LEU C 2 86  ? 384.925 354.480 281.033 1.00 106.89 ? 86  LEU A CD2   1 
ATOM   7293  N  N     . PHE C 2 87  ? 387.915 351.622 283.571 1.00 99.84  ? 87  PHE A N     1 
ATOM   7294  C  CA    . PHE C 2 87  ? 389.327 351.968 283.548 1.00 97.51  ? 87  PHE A CA    1 
ATOM   7295  C  C     . PHE C 2 87  ? 390.204 350.766 283.874 1.00 99.62  ? 87  PHE A C     1 
ATOM   7296  O  O     . PHE C 2 87  ? 389.786 349.815 284.538 1.00 95.00  ? 87  PHE A O     1 
ATOM   7297  C  CB    . PHE C 2 87  ? 389.619 353.097 284.534 1.00 95.92  ? 87  PHE A CB    1 
ATOM   7298  C  CG    . PHE C 2 87  ? 389.105 354.432 284.089 1.00 95.53  ? 87  PHE A CG    1 
ATOM   7299  C  CD1   . PHE C 2 87  ? 389.755 355.143 283.097 1.00 99.40  ? 87  PHE A CD1   1 
ATOM   7300  C  CD2   . PHE C 2 87  ? 387.973 354.978 284.663 1.00 96.44  ? 87  PHE A CD2   1 
ATOM   7301  C  CE1   . PHE C 2 87  ? 389.284 356.370 282.685 1.00 101.70 ? 87  PHE A CE1   1 
ATOM   7302  C  CE2   . PHE C 2 87  ? 387.497 356.206 284.256 1.00 98.41  ? 87  PHE A CE2   1 
ATOM   7303  C  CZ    . PHE C 2 87  ? 388.154 356.903 283.266 1.00 103.43 ? 87  PHE A CZ    1 
ATOM   7304  N  N     . HIS C 2 88  ? 391.435 350.824 283.386 1.00 104.15 ? 88  HIS A N     1 
ATOM   7305  C  CA    . HIS C 2 88  ? 392.436 349.835 283.759 1.00 101.79 ? 88  HIS A CA    1 
ATOM   7306  C  C     . HIS C 2 88  ? 392.728 349.980 285.253 1.00 103.45 ? 88  HIS A C     1 
ATOM   7307  O  O     . HIS C 2 88  ? 393.002 351.098 285.704 1.00 111.67 ? 88  HIS A O     1 
ATOM   7308  C  CB    . HIS C 2 88  ? 393.716 350.047 282.952 1.00 103.34 ? 88  HIS A CB    1 
ATOM   7309  C  CG    . HIS C 2 88  ? 394.449 348.785 282.625 1.00 102.77 ? 88  HIS A CG    1 
ATOM   7310  N  ND1   . HIS C 2 88  ? 394.761 347.837 283.573 1.00 98.45  ? 88  HIS A ND1   1 
ATOM   7311  C  CD2   . HIS C 2 88  ? 394.947 348.324 281.454 1.00 108.02 ? 88  HIS A CD2   1 
ATOM   7312  C  CE1   . HIS C 2 88  ? 395.413 346.841 282.999 1.00 106.10 ? 88  HIS A CE1   1 
ATOM   7313  N  NE2   . HIS C 2 88  ? 395.539 347.113 281.713 1.00 111.17 ? 88  HIS A NE2   1 
ATOM   7314  N  N     . PRO C 2 89  ? 392.653 348.908 286.061 1.00 102.82 ? 89  PRO A N     1 
ATOM   7315  C  CA    . PRO C 2 89  ? 392.997 349.076 287.486 1.00 105.17 ? 89  PRO A CA    1 
ATOM   7316  C  C     . PRO C 2 89  ? 394.431 349.508 287.724 1.00 102.32 ? 89  PRO A C     1 
ATOM   7317  O  O     . PRO C 2 89  ? 394.704 350.213 288.703 1.00 102.19 ? 89  PRO A O     1 
ATOM   7318  C  CB    . PRO C 2 89  ? 392.725 347.687 288.081 1.00 110.52 ? 89  PRO A CB    1 
ATOM   7319  C  CG    . PRO C 2 89  ? 391.769 347.061 287.162 1.00 112.88 ? 89  PRO A CG    1 
ATOM   7320  C  CD    . PRO C 2 89  ? 392.159 347.540 285.808 1.00 105.70 ? 89  PRO A CD    1 
ATOM   7321  N  N     . GLU C 2 90  ? 395.356 349.109 286.854 1.00 121.62 ? 90  GLU A N     1 
ATOM   7322  C  CA    . GLU C 2 90  ? 396.760 349.452 287.040 1.00 121.17 ? 90  GLU A CA    1 
ATOM   7323  C  C     . GLU C 2 90  ? 397.040 350.915 286.715 1.00 118.41 ? 90  GLU A C     1 
ATOM   7324  O  O     . GLU C 2 90  ? 397.911 351.524 287.345 1.00 120.37 ? 90  GLU A O     1 
ATOM   7325  C  CB    . GLU C 2 90  ? 397.683 348.561 286.187 1.00 124.06 ? 90  GLU A CB    1 
ATOM   7326  C  CG    . GLU C 2 90  ? 397.738 347.008 286.421 1.00 131.50 ? 90  GLU A CG    1 
ATOM   7327  C  CD    . GLU C 2 90  ? 396.405 346.280 286.547 1.00 136.45 ? 90  GLU A CD    1 
ATOM   7328  O  OE1   . GLU C 2 90  ? 396.377 345.181 287.142 1.00 131.65 ? 90  GLU A OE1   1 
ATOM   7329  O  OE2   . GLU C 2 90  ? 395.386 346.814 286.061 1.00 136.75 ? 90  GLU A OE2   1 
ATOM   7330  N  N     . GLN C 2 91  ? 396.337 351.488 285.733 1.00 108.96 ? 91  GLN A N     1 
ATOM   7331  C  CA    . GLN C 2 91  ? 396.600 352.873 285.347 1.00 106.38 ? 91  GLN A CA    1 
ATOM   7332  C  C     . GLN C 2 91  ? 396.227 353.853 286.449 1.00 109.12 ? 91  GLN A C     1 
ATOM   7333  O  O     . GLN C 2 91  ? 396.811 354.940 286.530 1.00 116.38 ? 91  GLN A O     1 
ATOM   7334  C  CB    . GLN C 2 91  ? 395.842 353.228 284.069 1.00 105.89 ? 91  GLN A CB    1 
ATOM   7335  C  CG    . GLN C 2 91  ? 396.581 352.871 282.786 1.00 114.80 ? 91  GLN A CG    1 
ATOM   7336  C  CD    . GLN C 2 91  ? 395.659 352.418 281.667 1.00 116.76 ? 91  GLN A CD    1 
ATOM   7337  O  OE1   . GLN C 2 91  ? 395.940 351.432 280.987 1.00 111.42 ? 91  GLN A OE1   1 
ATOM   7338  N  NE2   . GLN C 2 91  ? 394.564 353.145 281.456 1.00 120.59 ? 91  GLN A NE2   1 
ATOM   7339  N  N     . LEU C 2 92  ? 395.267 353.501 287.301 1.00 111.03 ? 92  LEU A N     1 
ATOM   7340  C  CA    . LEU C 2 92  ? 394.883 354.378 288.398 1.00 109.35 ? 92  LEU A CA    1 
ATOM   7341  C  C     . LEU C 2 92  ? 395.989 354.388 289.444 1.00 111.26 ? 92  LEU A C     1 
ATOM   7342  O  O     . LEU C 2 92  ? 396.024 353.533 290.335 1.00 117.80 ? 92  LEU A O     1 
ATOM   7343  C  CB    . LEU C 2 92  ? 393.554 353.924 289.006 1.00 107.32 ? 92  LEU A CB    1 
ATOM   7344  C  CG    . LEU C 2 92  ? 392.385 353.711 288.040 1.00 109.03 ? 92  LEU A CG    1 
ATOM   7345  C  CD1   . LEU C 2 92  ? 391.149 353.278 288.807 1.00 110.19 ? 92  LEU A CD1   1 
ATOM   7346  C  CD2   . LEU C 2 92  ? 392.094 354.962 287.233 1.00 104.68 ? 92  LEU A CD2   1 
ATOM   7347  N  N     . ILE C 2 93  ? 396.896 355.356 289.335 1.00 107.09 ? 93  ILE A N     1 
ATOM   7348  C  CA    . ILE C 2 93  ? 398.090 355.436 290.170 1.00 107.40 ? 93  ILE A CA    1 
ATOM   7349  C  C     . ILE C 2 93  ? 397.796 356.358 291.341 1.00 109.78 ? 93  ILE A C     1 
ATOM   7350  O  O     . ILE C 2 93  ? 397.356 357.498 291.146 1.00 113.06 ? 93  ILE A O     1 
ATOM   7351  C  CB    . ILE C 2 93  ? 399.300 355.940 289.364 1.00 107.12 ? 93  ILE A CB    1 
ATOM   7352  C  CG1   . ILE C 2 93  ? 399.703 354.935 288.279 1.00 110.66 ? 93  ILE A CG1   1 
ATOM   7353  C  CG2   . ILE C 2 93  ? 400.481 356.212 290.280 1.00 110.43 ? 93  ILE A CG2   1 
ATOM   7354  C  CD1   . ILE C 2 93  ? 400.441 355.564 287.133 1.00 112.45 ? 93  ILE A CD1   1 
ATOM   7355  N  N     . THR C 2 94  ? 398.063 355.874 292.555 1.00 110.63 ? 94  THR A N     1 
ATOM   7356  C  CA    . THR C 2 94  ? 397.780 356.593 293.791 1.00 109.51 ? 94  THR A CA    1 
ATOM   7357  C  C     . THR C 2 94  ? 399.041 356.666 294.634 1.00 107.68 ? 94  THR A C     1 
ATOM   7358  O  O     . THR C 2 94  ? 399.641 355.633 294.950 1.00 107.21 ? 94  THR A O     1 
ATOM   7359  C  CB    . THR C 2 94  ? 396.668 355.905 294.587 1.00 117.22 ? 94  THR A CB    1 
ATOM   7360  O  OG1   . THR C 2 94  ? 396.907 354.492 294.624 1.00 120.77 ? 94  THR A OG1   1 
ATOM   7361  C  CG2   . THR C 2 94  ? 395.314 356.171 293.952 1.00 114.77 ? 94  THR A CG2   1 
ATOM   7362  N  N     . GLY C 2 95  ? 399.438 357.885 294.996 1.00 108.33 ? 95  GLY A N     1 
ATOM   7363  C  CA    . GLY C 2 95  ? 400.502 358.068 295.957 1.00 111.65 ? 95  GLY A CA    1 
ATOM   7364  C  C     . GLY C 2 95  ? 400.001 357.905 297.376 1.00 112.67 ? 95  GLY A C     1 
ATOM   7365  O  O     . GLY C 2 95  ? 398.803 357.790 297.632 1.00 111.47 ? 95  GLY A O     1 
ATOM   7366  N  N     . LYS C 2 96  ? 400.949 357.910 298.314 1.00 120.00 ? 96  LYS A N     1 
ATOM   7367  C  CA    . LYS C 2 96  ? 400.620 357.632 299.708 1.00 119.71 ? 96  LYS A CA    1 
ATOM   7368  C  C     . LYS C 2 96  ? 400.116 358.876 300.430 1.00 118.63 ? 96  LYS A C     1 
ATOM   7369  O  O     . LYS C 2 96  ? 399.158 358.797 301.207 1.00 121.07 ? 96  LYS A O     1 
ATOM   7370  C  CB    . LYS C 2 96  ? 401.845 357.057 300.429 1.00 121.99 ? 96  LYS A CB    1 
ATOM   7371  C  CG    . LYS C 2 96  ? 402.237 355.600 300.087 1.00 122.50 ? 96  LYS A CG    1 
ATOM   7372  C  CD    . LYS C 2 96  ? 401.094 354.560 300.078 1.00 125.58 ? 96  LYS A CD    1 
ATOM   7373  C  CE    . LYS C 2 96  ? 400.267 354.513 301.370 1.00 126.30 ? 96  LYS A CE    1 
ATOM   7374  N  NZ    . LYS C 2 96  ? 398.993 353.758 301.179 1.00 126.19 ? 96  LYS A NZ    1 
ATOM   7375  N  N     . GLU C 2 97  ? 400.747 360.030 300.188 1.00 123.57 ? 97  GLU A N     1 
ATOM   7376  C  CA    . GLU C 2 97  ? 400.464 361.261 300.917 1.00 125.52 ? 97  GLU A CA    1 
ATOM   7377  C  C     . GLU C 2 97  ? 400.311 362.426 299.948 1.00 127.91 ? 97  GLU A C     1 
ATOM   7378  O  O     . GLU C 2 97  ? 400.909 362.446 298.869 1.00 129.71 ? 97  GLU A O     1 
ATOM   7379  C  CB    . GLU C 2 97  ? 401.574 361.563 301.933 1.00 127.65 ? 97  GLU A CB    1 
ATOM   7380  C  CG    . GLU C 2 97  ? 401.116 362.402 303.120 1.00 130.37 ? 97  GLU A CG    1 
ATOM   7381  C  CD    . GLU C 2 97  ? 402.178 362.540 304.195 1.00 130.45 ? 97  GLU A CD    1 
ATOM   7382  O  OE1   . GLU C 2 97  ? 403.203 361.830 304.126 1.00 129.83 ? 97  GLU A OE1   1 
ATOM   7383  O  OE2   . GLU C 2 97  ? 401.987 363.364 305.114 1.00 130.80 ? 97  GLU A OE2   1 
ATOM   7384  N  N     . ASP C 2 98  ? 399.503 363.401 300.356 1.00 128.22 ? 98  ASP A N     1 
ATOM   7385  C  CA    . ASP C 2 98  ? 399.177 364.555 299.533 1.00 125.35 ? 98  ASP A CA    1 
ATOM   7386  C  C     . ASP C 2 98  ? 400.362 365.514 299.434 1.00 125.72 ? 98  ASP A C     1 
ATOM   7387  O  O     . ASP C 2 98  ? 401.288 365.490 300.249 1.00 130.35 ? 98  ASP A O     1 
ATOM   7388  C  CB    . ASP C 2 98  ? 397.965 365.286 300.117 1.00 133.09 ? 98  ASP A CB    1 
ATOM   7389  C  CG    . ASP C 2 98  ? 397.294 366.200 299.115 1.00 134.79 ? 98  ASP A CG    1 
ATOM   7390  O  OD1   . ASP C 2 98  ? 397.786 367.332 298.929 1.00 139.11 ? 98  ASP A OD1   1 
ATOM   7391  O  OD2   . ASP C 2 98  ? 396.278 365.792 298.517 1.00 134.50 ? 98  ASP A OD2   1 
ATOM   7392  N  N     . ALA C 2 99  ? 400.318 366.372 298.412 1.00 110.78 ? 99  ALA A N     1 
ATOM   7393  C  CA    . ALA C 2 99  ? 401.307 367.426 298.221 1.00 110.04 ? 99  ALA A CA    1 
ATOM   7394  C  C     . ALA C 2 99  ? 401.047 368.673 299.060 1.00 114.28 ? 99  ALA A C     1 
ATOM   7395  O  O     . ALA C 2 99  ? 401.895 369.571 299.066 1.00 119.09 ? 99  ALA A O     1 
ATOM   7396  C  CB    . ALA C 2 99  ? 401.369 367.830 296.745 1.00 102.77 ? 99  ALA A CB    1 
ATOM   7397  N  N     . ALA C 2 100 ? 399.901 368.763 299.742 1.00 103.84 ? 100 ALA A N     1 
ATOM   7398  C  CA    . ALA C 2 100 ? 399.617 369.854 300.681 1.00 100.84 ? 100 ALA A CA    1 
ATOM   7399  C  C     . ALA C 2 100 ? 399.637 371.219 299.995 1.00 99.62  ? 100 ALA A C     1 
ATOM   7400  O  O     . ALA C 2 100 ? 400.027 372.225 300.589 1.00 108.51 ? 100 ALA A O     1 
ATOM   7401  C  CB    . ALA C 2 100 ? 400.595 369.835 301.856 1.00 106.05 ? 100 ALA A CB    1 
ATOM   7402  N  N     . ASN C 2 101 ? 399.201 371.254 298.734 1.00 91.86  ? 101 ASN A N     1 
ATOM   7403  C  CA    . ASN C 2 101 ? 399.162 372.475 297.921 1.00 95.83  ? 101 ASN A CA    1 
ATOM   7404  C  C     . ASN C 2 101 ? 400.549 373.116 297.788 1.00 91.47  ? 101 ASN A C     1 
ATOM   7405  O  O     . ASN C 2 101 ? 400.676 374.325 297.574 1.00 89.88  ? 101 ASN A O     1 
ATOM   7406  C  CB    . ASN C 2 101 ? 398.122 373.472 298.473 1.00 98.00  ? 101 ASN A CB    1 
ATOM   7407  C  CG    . ASN C 2 101 ? 396.914 373.643 297.555 1.00 105.15 ? 101 ASN A CG    1 
ATOM   7408  O  OD1   . ASN C 2 101 ? 396.527 372.739 296.815 1.00 107.11 ? 101 ASN A OD1   1 
ATOM   7409  N  ND2   . ASN C 2 101 ? 396.306 374.814 297.616 1.00 103.41 ? 101 ASN A ND2   1 
ATOM   7410  N  N     . ASN C 2 102 ? 401.595 372.293 297.838 1.00 102.20 ? 102 ASN A N     1 
ATOM   7411  C  CA    . ASN C 2 102 ? 402.983 372.738 297.835 1.00 102.51 ? 102 ASN A CA    1 
ATOM   7412  C  C     . ASN C 2 102 ? 403.633 372.270 296.540 1.00 100.87 ? 102 ASN A C     1 
ATOM   7413  O  O     . ASN C 2 102 ? 403.746 371.060 296.298 1.00 104.01 ? 102 ASN A O     1 
ATOM   7414  C  CB    . ASN C 2 102 ? 403.717 372.185 299.056 1.00 100.13 ? 102 ASN A CB    1 
ATOM   7415  C  CG    . ASN C 2 102 ? 405.045 372.863 299.306 1.00 101.87 ? 102 ASN A CG    1 
ATOM   7416  O  OD1   . ASN C 2 102 ? 405.628 373.469 298.409 1.00 111.88 ? 102 ASN A OD1   1 
ATOM   7417  N  ND2   . ASN C 2 102 ? 405.538 372.754 300.531 1.00 101.30 ? 102 ASN A ND2   1 
ATOM   7418  N  N     . TYR C 2 103 ? 404.049 373.232 295.709 1.00 94.87  ? 103 TYR A N     1 
ATOM   7419  C  CA    . TYR C 2 103 ? 404.705 372.897 294.448 1.00 93.00  ? 103 TYR A CA    1 
ATOM   7420  C  C     . TYR C 2 103 ? 405.988 372.121 294.691 1.00 94.07  ? 103 TYR A C     1 
ATOM   7421  O  O     . TYR C 2 103 ? 406.288 371.172 293.963 1.00 105.80 ? 103 TYR A O     1 
ATOM   7422  C  CB    . TYR C 2 103 ? 404.992 374.170 293.641 1.00 95.78  ? 103 TYR A CB    1 
ATOM   7423  C  CG    . TYR C 2 103 ? 405.812 373.960 292.379 1.00 96.67  ? 103 TYR A CG    1 
ATOM   7424  C  CD1   . TYR C 2 103 ? 405.199 373.671 291.171 1.00 99.72  ? 103 TYR A CD1   1 
ATOM   7425  C  CD2   . TYR C 2 103 ? 407.198 374.101 292.389 1.00 94.24  ? 103 TYR A CD2   1 
ATOM   7426  C  CE1   . TYR C 2 103 ? 405.944 373.490 290.022 1.00 99.31  ? 103 TYR A CE1   1 
ATOM   7427  C  CE2   . TYR C 2 103 ? 407.943 373.915 291.252 1.00 89.88  ? 103 TYR A CE2   1 
ATOM   7428  C  CZ    . TYR C 2 103 ? 407.313 373.617 290.072 1.00 97.16  ? 103 TYR A CZ    1 
ATOM   7429  O  OH    . TYR C 2 103 ? 408.062 373.439 288.936 1.00 102.36 ? 103 TYR A OH    1 
ATOM   7430  N  N     . ALA C 2 104 ? 406.768 372.524 295.694 1.00 91.49  ? 104 ALA A N     1 
ATOM   7431  C  CA    . ALA C 2 104 ? 408.027 371.843 295.971 1.00 97.87  ? 104 ALA A CA    1 
ATOM   7432  C  C     . ALA C 2 104 ? 407.790 370.397 296.385 1.00 105.57 ? 104 ALA A C     1 
ATOM   7433  O  O     . ALA C 2 104 ? 408.491 369.488 295.923 1.00 110.98 ? 104 ALA A O     1 
ATOM   7434  C  CB    . ALA C 2 104 ? 408.788 372.596 297.058 1.00 103.78 ? 104 ALA A CB    1 
ATOM   7435  N  N     . ARG C 2 105 ? 406.792 370.167 297.239 1.00 106.95 ? 105 ARG A N     1 
ATOM   7436  C  CA    . ARG C 2 105 ? 406.470 368.812 297.673 1.00 104.00 ? 105 ARG A CA    1 
ATOM   7437  C  C     . ARG C 2 105 ? 405.995 367.966 296.500 1.00 105.71 ? 105 ARG A C     1 
ATOM   7438  O  O     . ARG C 2 105 ? 406.449 366.832 296.308 1.00 112.20 ? 105 ARG A O     1 
ATOM   7439  C  CB    . ARG C 2 105 ? 405.402 368.857 298.766 1.00 103.34 ? 105 ARG A CB    1 
ATOM   7440  C  CG    . ARG C 2 105 ? 405.170 367.543 299.483 1.00 108.13 ? 105 ARG A CG    1 
ATOM   7441  C  CD    . ARG C 2 105 ? 404.269 367.729 300.694 1.00 108.95 ? 105 ARG A CD    1 
ATOM   7442  N  NE    . ARG C 2 105 ? 403.660 366.476 301.123 1.00 112.88 ? 105 ARG A NE    1 
ATOM   7443  C  CZ    . ARG C 2 105 ? 404.286 365.503 301.775 1.00 113.33 ? 105 ARG A CZ    1 
ATOM   7444  N  NH1   . ARG C 2 105 ? 405.560 365.599 302.127 1.00 112.32 ? 105 ARG A NH1   1 
ATOM   7445  N  NH2   . ARG C 2 105 ? 403.614 364.399 302.085 1.00 116.62 ? 105 ARG A NH2   1 
ATOM   7446  N  N     . GLY C 2 106 ? 405.077 368.506 295.697 1.00 98.47  ? 106 GLY A N     1 
ATOM   7447  C  CA    . GLY C 2 106 ? 404.559 367.750 294.571 1.00 101.72 ? 106 GLY A CA    1 
ATOM   7448  C  C     . GLY C 2 106 ? 405.564 367.520 293.462 1.00 94.70  ? 106 GLY A C     1 
ATOM   7449  O  O     . GLY C 2 106 ? 405.451 366.524 292.739 1.00 93.61  ? 106 GLY A O     1 
ATOM   7450  N  N     . HIS C 2 107 ? 406.547 368.409 293.317 1.00 100.13 ? 107 HIS A N     1 
ATOM   7451  C  CA    . HIS C 2 107 ? 407.495 368.320 292.215 1.00 94.16  ? 107 HIS A CA    1 
ATOM   7452  C  C     . HIS C 2 107 ? 408.698 367.462 292.580 1.00 99.26  ? 107 HIS A C     1 
ATOM   7453  O  O     . HIS C 2 107 ? 409.071 366.560 291.825 1.00 103.80 ? 107 HIS A O     1 
ATOM   7454  C  CB    . HIS C 2 107 ? 407.947 369.722 291.807 1.00 97.14  ? 107 HIS A CB    1 
ATOM   7455  C  CG    . HIS C 2 107 ? 408.772 369.753 290.560 1.00 99.31  ? 107 HIS A CG    1 
ATOM   7456  N  ND1   . HIS C 2 107 ? 408.215 369.805 289.301 1.00 105.48 ? 107 HIS A ND1   1 
ATOM   7457  C  CD2   . HIS C 2 107 ? 410.114 369.744 290.377 1.00 98.65  ? 107 HIS A CD2   1 
ATOM   7458  C  CE1   . HIS C 2 107 ? 409.177 369.824 288.396 1.00 98.97  ? 107 HIS A CE1   1 
ATOM   7459  N  NE2   . HIS C 2 107 ? 410.339 369.788 289.023 1.00 97.11  ? 107 HIS A NE2   1 
ATOM   7460  N  N     . TYR C 2 108 ? 409.319 367.726 293.733 1.00 102.74 ? 108 TYR A N     1 
ATOM   7461  C  CA    . TYR C 2 108 ? 410.574 367.073 294.086 1.00 101.51 ? 108 TYR A CA    1 
ATOM   7462  C  C     . TYR C 2 108 ? 410.358 365.818 294.926 1.00 107.88 ? 108 TYR A C     1 
ATOM   7463  O  O     . TYR C 2 108 ? 410.524 364.698 294.427 1.00 117.15 ? 108 TYR A O     1 
ATOM   7464  C  CB    . TYR C 2 108 ? 411.454 368.071 294.848 1.00 97.54  ? 108 TYR A CB    1 
ATOM   7465  C  CG    . TYR C 2 108 ? 412.029 369.163 293.979 1.00 101.53 ? 108 TYR A CG    1 
ATOM   7466  C  CD1   . TYR C 2 108 ? 413.192 368.963 293.251 1.00 105.58 ? 108 TYR A CD1   1 
ATOM   7467  C  CD2   . TYR C 2 108 ? 411.402 370.397 293.883 1.00 99.34  ? 108 TYR A CD2   1 
ATOM   7468  C  CE1   . TYR C 2 108 ? 413.716 369.962 292.456 1.00 103.02 ? 108 TYR A CE1   1 
ATOM   7469  C  CE2   . TYR C 2 108 ? 411.917 371.401 293.092 1.00 99.78  ? 108 TYR A CE2   1 
ATOM   7470  C  CZ    . TYR C 2 108 ? 413.074 371.178 292.380 1.00 103.84 ? 108 TYR A CZ    1 
ATOM   7471  O  OH    . TYR C 2 108 ? 413.590 372.177 291.590 1.00 111.66 ? 108 TYR A OH    1 
ATOM   7472  N  N     . THR C 2 109 ? 409.867 365.981 296.155 1.00 108.63 ? 109 THR A N     1 
ATOM   7473  C  CA    . THR C 2 109 ? 409.941 364.896 297.129 1.00 112.28 ? 109 THR A CA    1 
ATOM   7474  C  C     . THR C 2 109 ? 408.941 363.793 296.812 1.00 113.59 ? 109 THR A C     1 
ATOM   7475  O  O     . THR C 2 109 ? 409.326 362.663 296.494 1.00 118.73 ? 109 THR A O     1 
ATOM   7476  C  CB    . THR C 2 109 ? 409.704 365.437 298.541 1.00 113.59 ? 109 THR A CB    1 
ATOM   7477  O  OG1   . THR C 2 109 ? 408.538 366.268 298.550 1.00 117.72 ? 109 THR A OG1   1 
ATOM   7478  C  CG2   . THR C 2 109 ? 410.899 366.247 299.009 1.00 118.49 ? 109 THR A CG2   1 
ATOM   7479  N  N     . ILE C 2 110 ? 407.650 364.109 296.877 1.00 107.51 ? 110 ILE A N     1 
ATOM   7480  C  CA    . ILE C 2 110 ? 406.641 363.094 296.602 1.00 108.86 ? 110 ILE A CA    1 
ATOM   7481  C  C     . ILE C 2 110 ? 406.589 362.782 295.109 1.00 111.08 ? 110 ILE A C     1 
ATOM   7482  O  O     . ILE C 2 110 ? 406.188 361.680 294.719 1.00 113.37 ? 110 ILE A O     1 
ATOM   7483  C  CB    . ILE C 2 110 ? 405.260 363.531 297.137 1.00 108.85 ? 110 ILE A CB    1 
ATOM   7484  C  CG1   . ILE C 2 110 ? 405.339 364.033 298.594 1.00 108.02 ? 110 ILE A CG1   1 
ATOM   7485  C  CG2   . ILE C 2 110 ? 404.251 362.382 297.026 1.00 112.31 ? 110 ILE A CG2   1 
ATOM   7486  C  CD1   . ILE C 2 110 ? 405.962 363.063 299.594 1.00 110.06 ? 110 ILE A CD1   1 
ATOM   7487  N  N     . GLY C 2 111 ? 406.982 363.728 294.255 1.00 110.43 ? 111 GLY A N     1 
ATOM   7488  C  CA    . GLY C 2 111 ? 406.951 363.477 292.824 1.00 110.52 ? 111 GLY A CA    1 
ATOM   7489  C  C     . GLY C 2 111 ? 407.964 362.442 292.371 1.00 113.47 ? 111 GLY A C     1 
ATOM   7490  O  O     . GLY C 2 111 ? 407.678 361.633 291.480 1.00 116.56 ? 111 GLY A O     1 
ATOM   7491  N  N     . LYS C 2 112 ? 409.176 362.479 292.938 1.00 122.25 ? 112 LYS A N     1 
ATOM   7492  C  CA    . LYS C 2 112 ? 410.214 361.564 292.474 1.00 120.93 ? 112 LYS A CA    1 
ATOM   7493  C  C     . LYS C 2 112 ? 409.928 360.110 292.836 1.00 126.26 ? 112 LYS A C     1 
ATOM   7494  O  O     . LYS C 2 112 ? 410.493 359.212 292.202 1.00 128.83 ? 112 LYS A O     1 
ATOM   7495  C  CB    . LYS C 2 112 ? 411.579 361.999 293.019 1.00 126.52 ? 112 LYS A CB    1 
ATOM   7496  C  CG    . LYS C 2 112 ? 411.920 361.518 294.426 1.00 128.96 ? 112 LYS A CG    1 
ATOM   7497  C  CD    . LYS C 2 112 ? 413.070 362.337 295.005 1.00 128.18 ? 112 LYS A CD    1 
ATOM   7498  C  CE    . LYS C 2 112 ? 413.869 361.566 296.045 1.00 126.92 ? 112 LYS A CE    1 
ATOM   7499  N  NZ    . LYS C 2 112 ? 413.062 361.255 297.254 1.00 127.87 ? 112 LYS A NZ    1 
ATOM   7500  N  N     . GLU C 2 113 ? 409.072 359.851 293.827 1.00 139.66 ? 113 GLU A N     1 
ATOM   7501  C  CA    . GLU C 2 113 ? 408.756 358.465 294.167 1.00 140.30 ? 113 GLU A CA    1 
ATOM   7502  C  C     . GLU C 2 113 ? 407.905 357.801 293.088 1.00 141.41 ? 113 GLU A C     1 
ATOM   7503  O  O     . GLU C 2 113 ? 408.108 356.621 292.776 1.00 142.63 ? 113 GLU A O     1 
ATOM   7504  C  CB    . GLU C 2 113 ? 408.046 358.379 295.525 1.00 138.45 ? 113 GLU A CB    1 
ATOM   7505  C  CG    . GLU C 2 113 ? 408.819 358.750 296.831 1.00 143.42 ? 113 GLU A CG    1 
ATOM   7506  C  CD    . GLU C 2 113 ? 408.020 358.708 298.146 1.00 145.90 ? 113 GLU A CD    1 
ATOM   7507  O  OE1   . GLU C 2 113 ? 406.777 358.574 298.154 1.00 145.99 ? 113 GLU A OE1   1 
ATOM   7508  O  OE2   . GLU C 2 113 ? 408.665 358.839 299.207 1.00 145.48 ? 113 GLU A OE2   1 
ATOM   7509  N  N     . ILE C 2 114 ? 406.967 358.544 292.497 1.00 118.15 ? 114 ILE A N     1 
ATOM   7510  C  CA    . ILE C 2 114 ? 405.885 357.989 291.683 1.00 116.04 ? 114 ILE A CA    1 
ATOM   7511  C  C     . ILE C 2 114 ? 406.008 358.349 290.202 1.00 114.00 ? 114 ILE A C     1 
ATOM   7512  O  O     . ILE C 2 114 ? 405.272 357.773 289.366 1.00 118.25 ? 114 ILE A O     1 
ATOM   7513  C  CB    . ILE C 2 114 ? 404.522 358.433 292.258 1.00 111.49 ? 114 ILE A CB    1 
ATOM   7514  C  CG1   . ILE C 2 114 ? 403.420 357.407 291.979 1.00 115.37 ? 114 ILE A CG1   1 
ATOM   7515  C  CG2   . ILE C 2 114 ? 404.114 359.823 291.762 1.00 113.65 ? 114 ILE A CG2   1 
ATOM   7516  C  CD1   . ILE C 2 114 ? 402.144 357.695 292.746 1.00 113.15 ? 114 ILE A CD1   1 
ATOM   7517  N  N     . ILE C 2 115 ? 406.920 359.264 289.842 1.00 115.70 ? 115 ILE A N     1 
ATOM   7518  C  CA    . ILE C 2 115 ? 407.076 359.662 288.445 1.00 116.24 ? 115 ILE A CA    1 
ATOM   7519  C  C     . ILE C 2 115 ? 407.505 358.479 287.582 1.00 121.98 ? 115 ILE A C     1 
ATOM   7520  O  O     . ILE C 2 115 ? 407.101 358.371 286.419 1.00 127.90 ? 115 ILE A O     1 
ATOM   7521  C  CB    . ILE C 2 115 ? 408.070 360.843 288.343 1.00 114.91 ? 115 ILE A CB    1 
ATOM   7522  C  CG1   . ILE C 2 115 ? 408.154 361.424 286.921 1.00 114.92 ? 115 ILE A CG1   1 
ATOM   7523  C  CG2   . ILE C 2 115 ? 409.488 360.440 288.781 1.00 120.96 ? 115 ILE A CG2   1 
ATOM   7524  C  CD1   . ILE C 2 115 ? 406.862 362.008 286.388 1.00 117.29 ? 115 ILE A CD1   1 
ATOM   7525  N  N     . ASP C 2 116 ? 408.334 357.584 288.127 1.00 127.15 ? 116 ASP A N     1 
ATOM   7526  C  CA    . ASP C 2 116 ? 408.814 356.452 287.337 1.00 128.20 ? 116 ASP A CA    1 
ATOM   7527  C  C     . ASP C 2 116 ? 407.675 355.514 286.959 1.00 129.01 ? 116 ASP A C     1 
ATOM   7528  O  O     . ASP C 2 116 ? 407.585 355.073 285.807 1.00 130.33 ? 116 ASP A O     1 
ATOM   7529  C  CB    . ASP C 2 116 ? 409.897 355.690 288.100 1.00 132.45 ? 116 ASP A CB    1 
ATOM   7530  C  CG    . ASP C 2 116 ? 411.292 356.169 287.757 1.00 134.51 ? 116 ASP A CG    1 
ATOM   7531  O  OD1   . ASP C 2 116 ? 412.201 355.322 287.636 1.00 135.99 ? 116 ASP A OD1   1 
ATOM   7532  O  OD2   . ASP C 2 116 ? 411.478 357.394 287.605 1.00 129.90 ? 116 ASP A OD2   1 
ATOM   7533  N  N     . LEU C 2 117 ? 406.789 355.210 287.909 1.00 126.03 ? 117 LEU A N     1 
ATOM   7534  C  CA    . LEU C 2 117 ? 405.641 354.362 287.603 1.00 126.22 ? 117 LEU A CA    1 
ATOM   7535  C  C     . LEU C 2 117 ? 404.716 355.028 286.594 1.00 126.14 ? 117 LEU A C     1 
ATOM   7536  O  O     . LEU C 2 117 ? 404.209 354.366 285.675 1.00 127.09 ? 117 LEU A O     1 
ATOM   7537  C  CB    . LEU C 2 117 ? 404.876 354.030 288.888 1.00 125.58 ? 117 LEU A CB    1 
ATOM   7538  C  CG    . LEU C 2 117 ? 403.945 352.807 288.959 1.00 125.69 ? 117 LEU A CG    1 
ATOM   7539  C  CD1   . LEU C 2 117 ? 404.563 351.516 288.429 1.00 128.25 ? 117 LEU A CD1   1 
ATOM   7540  C  CD2   . LEU C 2 117 ? 403.472 352.614 290.392 1.00 125.02 ? 117 LEU A CD2   1 
ATOM   7541  N  N     . VAL C 2 118 ? 404.484 356.338 286.749 1.00 121.12 ? 118 VAL A N     1 
ATOM   7542  C  CA    . VAL C 2 118 ? 403.608 357.040 285.808 1.00 119.97 ? 118 VAL A CA    1 
ATOM   7543  C  C     . VAL C 2 118 ? 404.189 356.998 284.398 1.00 121.93 ? 118 VAL A C     1 
ATOM   7544  O  O     . VAL C 2 118 ? 403.476 356.720 283.420 1.00 124.48 ? 118 VAL A O     1 
ATOM   7545  C  CB    . VAL C 2 118 ? 403.357 358.485 286.280 1.00 117.04 ? 118 VAL A CB    1 
ATOM   7546  C  CG1   . VAL C 2 118 ? 402.562 359.254 285.236 1.00 119.49 ? 118 VAL A CG1   1 
ATOM   7547  C  CG2   . VAL C 2 118 ? 402.593 358.500 287.600 1.00 118.04 ? 118 VAL A CG2   1 
ATOM   7548  N  N     . LEU C 2 119 ? 405.492 357.248 284.272 1.00 124.77 ? 119 LEU A N     1 
ATOM   7549  C  CA    . LEU C 2 119 ? 406.120 357.196 282.959 1.00 124.39 ? 119 LEU A CA    1 
ATOM   7550  C  C     . LEU C 2 119 ? 406.130 355.783 282.395 1.00 127.03 ? 119 LEU A C     1 
ATOM   7551  O  O     . LEU C 2 119 ? 406.034 355.611 281.178 1.00 130.10 ? 119 LEU A O     1 
ATOM   7552  C  CB    . LEU C 2 119 ? 407.540 357.749 283.036 1.00 120.76 ? 119 LEU A CB    1 
ATOM   7553  C  CG    . LEU C 2 119 ? 407.648 359.241 283.361 1.00 120.09 ? 119 LEU A CG    1 
ATOM   7554  C  CD1   . LEU C 2 119 ? 409.073 359.586 283.749 1.00 128.15 ? 119 LEU A CD1   1 
ATOM   7555  C  CD2   . LEU C 2 119 ? 407.186 360.102 282.192 1.00 118.26 ? 119 LEU A CD2   1 
ATOM   7556  N  N     . ASP C 2 120 ? 406.236 354.763 283.252 1.00 135.10 ? 120 ASP A N     1 
ATOM   7557  C  CA    . ASP C 2 120 ? 406.188 353.387 282.758 1.00 135.23 ? 120 ASP A CA    1 
ATOM   7558  C  C     . ASP C 2 120 ? 404.822 353.066 282.162 1.00 135.68 ? 120 ASP A C     1 
ATOM   7559  O  O     . ASP C 2 120 ? 404.732 352.453 281.088 1.00 136.64 ? 120 ASP A O     1 
ATOM   7560  C  CB    . ASP C 2 120 ? 406.513 352.395 283.889 1.00 137.78 ? 120 ASP A CB    1 
ATOM   7561  C  CG    . ASP C 2 120 ? 407.905 351.745 283.770 1.00 138.21 ? 120 ASP A CG    1 
ATOM   7562  O  OD1   . ASP C 2 120 ? 408.591 351.837 282.727 1.00 134.90 ? 120 ASP A OD1   1 
ATOM   7563  O  OD2   . ASP C 2 120 ? 408.321 351.118 284.767 1.00 140.11 ? 120 ASP A OD2   1 
ATOM   7564  N  N     . ARG C 2 121 ? 403.743 353.473 282.840 1.00 129.31 ? 121 ARG A N     1 
ATOM   7565  C  CA    . ARG C 2 121 ? 402.413 353.229 282.282 1.00 124.29 ? 121 ARG A CA    1 
ATOM   7566  C  C     . ARG C 2 121 ? 402.203 354.009 280.989 1.00 124.94 ? 121 ARG A C     1 
ATOM   7567  O  O     . ARG C 2 121 ? 401.596 353.493 280.037 1.00 125.18 ? 121 ARG A O     1 
ATOM   7568  C  CB    . ARG C 2 121 ? 401.320 353.588 283.289 1.00 120.84 ? 121 ARG A CB    1 
ATOM   7569  C  CG    . ARG C 2 121 ? 401.362 352.900 284.661 1.00 125.46 ? 121 ARG A CG    1 
ATOM   7570  C  CD    . ARG C 2 121 ? 401.878 351.452 284.672 1.00 128.61 ? 121 ARG A CD    1 
ATOM   7571  N  NE    . ARG C 2 121 ? 401.285 350.560 283.677 1.00 131.75 ? 121 ARG A NE    1 
ATOM   7572  C  CZ    . ARG C 2 121 ? 399.992 350.296 283.520 1.00 132.02 ? 121 ARG A CZ    1 
ATOM   7573  N  NH1   . ARG C 2 121 ? 399.077 350.731 284.368 1.00 135.05 ? 121 ARG A NH1   1 
ATOM   7574  N  NH2   . ARG C 2 121 ? 399.607 349.554 282.486 1.00 128.28 ? 121 ARG A NH2   1 
ATOM   7575  N  N     . ILE C 2 122 ? 402.694 355.250 280.935 1.00 112.80 ? 122 ILE A N     1 
ATOM   7576  C  CA    . ILE C 2 122 ? 402.573 356.031 279.707 1.00 104.83 ? 122 ILE A CA    1 
ATOM   7577  C  C     . ILE C 2 122 ? 403.353 355.365 278.579 1.00 108.93 ? 122 ILE A C     1 
ATOM   7578  O  O     . ILE C 2 122 ? 402.903 355.341 277.426 1.00 118.61 ? 122 ILE A O     1 
ATOM   7579  C  CB    . ILE C 2 122 ? 403.034 357.482 279.943 1.00 107.82 ? 122 ILE A CB    1 
ATOM   7580  C  CG1   . ILE C 2 122 ? 402.027 358.229 280.820 1.00 105.78 ? 122 ILE A CG1   1 
ATOM   7581  C  CG2   . ILE C 2 122 ? 403.195 358.234 278.619 1.00 114.90 ? 122 ILE A CG2   1 
ATOM   7582  C  CD1   . ILE C 2 122 ? 402.630 359.364 281.603 1.00 111.40 ? 122 ILE A CD1   1 
ATOM   7583  N  N     . ARG C 2 123 ? 404.527 354.812 278.891 1.00 122.76 ? 123 ARG A N     1 
ATOM   7584  C  CA    . ARG C 2 123 ? 405.314 354.115 277.881 1.00 123.80 ? 123 ARG A CA    1 
ATOM   7585  C  C     . ARG C 2 123 ? 404.587 352.885 277.365 1.00 122.46 ? 123 ARG A C     1 
ATOM   7586  O  O     . ARG C 2 123 ? 404.623 352.598 276.167 1.00 128.89 ? 123 ARG A O     1 
ATOM   7587  C  CB    . ARG C 2 123 ? 406.676 353.719 278.446 1.00 128.82 ? 123 ARG A CB    1 
ATOM   7588  C  CG    . ARG C 2 123 ? 407.743 353.519 277.378 1.00 129.61 ? 123 ARG A CG    1 
ATOM   7589  C  CD    . ARG C 2 123 ? 409.132 353.395 277.976 1.00 130.20 ? 123 ARG A CD    1 
ATOM   7590  N  NE    . ARG C 2 123 ? 409.598 354.664 278.535 1.00 132.00 ? 123 ARG A NE    1 
ATOM   7591  C  CZ    . ARG C 2 123 ? 409.680 354.982 279.825 1.00 130.10 ? 123 ARG A CZ    1 
ATOM   7592  N  NH1   . ARG C 2 123 ? 409.284 354.158 280.786 1.00 127.77 ? 123 ARG A NH1   1 
ATOM   7593  N  NH2   . ARG C 2 123 ? 410.163 356.174 280.164 1.00 127.15 ? 123 ARG A NH2   1 
ATOM   7594  N  N     . LYS C 2 124 ? 403.931 352.138 278.254 1.00 118.14 ? 124 LYS A N     1 
ATOM   7595  C  CA    . LYS C 2 124 ? 403.213 350.947 277.808 1.00 117.88 ? 124 LYS A CA    1 
ATOM   7596  C  C     . LYS C 2 124 ? 402.035 351.319 276.910 1.00 120.25 ? 124 LYS A C     1 
ATOM   7597  O  O     . LYS C 2 124 ? 401.802 350.678 275.872 1.00 123.51 ? 124 LYS A O     1 
ATOM   7598  C  CB    . LYS C 2 124 ? 402.753 350.136 279.020 1.00 117.29 ? 124 LYS A CB    1 
ATOM   7599  C  CG    . LYS C 2 124 ? 402.302 348.707 278.690 1.00 120.91 ? 124 LYS A CG    1 
ATOM   7600  C  CD    . LYS C 2 124 ? 401.663 347.946 279.871 1.00 123.18 ? 124 LYS A CD    1 
ATOM   7601  C  CE    . LYS C 2 124 ? 402.449 348.025 281.187 1.00 122.73 ? 124 LYS A CE    1 
ATOM   7602  N  NZ    . LYS C 2 124 ? 403.864 347.567 281.065 1.00 120.08 ? 124 LYS A NZ    1 
ATOM   7603  N  N     . LEU C 2 125 ? 401.296 352.372 277.276 1.00 115.98 ? 125 LEU A N     1 
ATOM   7604  C  CA    . LEU C 2 125 ? 400.194 352.816 276.425 1.00 114.35 ? 125 LEU A CA    1 
ATOM   7605  C  C     . LEU C 2 125 ? 400.699 353.301 275.068 1.00 118.01 ? 125 LEU A C     1 
ATOM   7606  O  O     . LEU C 2 125 ? 400.119 352.967 274.025 1.00 126.33 ? 125 LEU A O     1 
ATOM   7607  C  CB    . LEU C 2 125 ? 399.396 353.916 277.127 1.00 109.90 ? 125 LEU A CB    1 
ATOM   7608  C  CG    . LEU C 2 125 ? 398.410 353.474 278.216 1.00 111.10 ? 125 LEU A CG    1 
ATOM   7609  C  CD1   . LEU C 2 125 ? 397.941 354.674 279.023 1.00 109.09 ? 125 LEU A CD1   1 
ATOM   7610  C  CD2   . LEU C 2 125 ? 397.212 352.732 277.630 1.00 113.70 ? 125 LEU A CD2   1 
ATOM   7611  N  N     . ALA C 2 126 ? 401.795 354.064 275.056 1.00 125.96 ? 126 ALA A N     1 
ATOM   7612  C  CA    . ALA C 2 126 ? 402.364 354.515 273.790 1.00 123.27 ? 126 ALA A CA    1 
ATOM   7613  C  C     . ALA C 2 126 ? 402.883 353.348 272.962 1.00 126.35 ? 126 ALA A C     1 
ATOM   7614  O  O     . ALA C 2 126 ? 402.813 353.386 271.728 1.00 130.22 ? 126 ALA A O     1 
ATOM   7615  C  CB    . ALA C 2 126 ? 403.485 355.518 274.045 1.00 127.41 ? 126 ALA A CB    1 
ATOM   7616  N  N     . ASP C 2 127 ? 403.434 352.334 273.626 1.00 135.68 ? 127 ASP A N     1 
ATOM   7617  C  CA    . ASP C 2 127 ? 403.914 351.135 272.892 1.00 135.29 ? 127 ASP A CA    1 
ATOM   7618  C  C     . ASP C 2 127 ? 402.721 350.475 272.196 1.00 134.75 ? 127 ASP A C     1 
ATOM   7619  O  O     . ASP C 2 127 ? 402.864 350.087 271.023 1.00 132.85 ? 127 ASP A O     1 
ATOM   7620  C  CB    . ASP C 2 127 ? 404.649 350.172 273.825 1.00 138.43 ? 127 ASP A CB    1 
ATOM   7621  C  CG    . ASP C 2 127 ? 405.998 350.696 274.286 1.00 140.42 ? 127 ASP A CG    1 
ATOM   7622  O  OD1   . ASP C 2 127 ? 406.373 351.805 273.856 1.00 138.96 ? 127 ASP A OD1   1 
ATOM   7623  O  OD2   . ASP C 2 127 ? 406.659 349.995 275.077 1.00 138.60 ? 127 ASP A OD2   1 
ATOM   7624  N  N     . GLN C 2 128 ? 401.571 350.417 272.874 1.00 138.79 ? 128 GLN A N     1 
ATOM   7625  C  CA    . GLN C 2 128 ? 400.341 349.860 272.249 1.00 137.93 ? 128 GLN A CA    1 
ATOM   7626  C  C     . GLN C 2 128 ? 399.890 350.788 271.116 1.00 139.80 ? 128 GLN A C     1 
ATOM   7627  O  O     . GLN C 2 128 ? 399.413 350.269 270.088 1.00 138.28 ? 128 GLN A O     1 
ATOM   7628  C  CB    . GLN C 2 128 ? 399.234 349.724 273.294 1.00 137.43 ? 128 GLN A CB    1 
ATOM   7629  C  CG    . GLN C 2 128 ? 399.636 348.893 274.503 1.00 141.67 ? 128 GLN A CG    1 
ATOM   7630  C  CD    . GLN C 2 128 ? 398.786 349.203 275.710 1.00 143.77 ? 128 GLN A CD    1 
ATOM   7631  O  OE1   . GLN C 2 128 ? 397.868 350.019 275.654 1.00 140.73 ? 128 GLN A OE1   1 
ATOM   7632  N  NE2   . GLN C 2 128 ? 399.088 348.549 276.819 1.00 142.60 ? 128 GLN A NE2   1 
ATOM   7633  N  N     . CYS C 2 129 ? 400.008 352.106 271.311 1.00 149.16 ? 129 CYS A N     1 
ATOM   7634  C  CA    . CYS C 2 129 ? 399.513 353.085 270.303 1.00 144.71 ? 129 CYS A CA    1 
ATOM   7635  C  C     . CYS C 2 129 ? 400.180 352.849 268.944 1.00 145.60 ? 129 CYS A C     1 
ATOM   7636  O  O     . CYS C 2 129 ? 401.423 352.907 268.882 1.00 147.56 ? 129 CYS A O     1 
ATOM   7637  C  CB    . CYS C 2 129 ? 399.784 354.515 270.757 1.00 145.23 ? 129 CYS A CB    1 
ATOM   7638  S  SG    . CYS C 2 129 ? 398.873 354.981 272.252 1.00 158.10 ? 129 CYS A SG    1 
ATOM   7639  N  N     . THR C 2 130 ? 399.380 352.598 267.903 1.00 135.12 ? 130 THR A N     1 
ATOM   7640  C  CA    . THR C 2 130 ? 399.929 352.418 266.532 1.00 134.62 ? 130 THR A CA    1 
ATOM   7641  C  C     . THR C 2 130 ? 400.385 353.776 265.989 1.00 135.07 ? 130 THR A C     1 
ATOM   7642  O  O     . THR C 2 130 ? 401.526 353.855 265.493 1.00 136.33 ? 130 THR A O     1 
ATOM   7643  C  CB    . THR C 2 130 ? 398.886 351.782 265.606 1.00 134.95 ? 130 THR A CB    1 
ATOM   7644  O  OG1   . THR C 2 130 ? 397.802 352.702 265.468 1.00 138.34 ? 130 THR A OG1   1 
ATOM   7645  C  CG2   . THR C 2 130 ? 398.370 350.459 266.126 1.00 133.28 ? 130 THR A CG2   1 
ATOM   7646  N  N     . GLY C 2 131 ? 399.527 354.796 266.083 1.00 129.38 ? 131 GLY A N     1 
ATOM   7647  C  CA    . GLY C 2 131 ? 399.882 356.153 265.621 1.00 126.40 ? 131 GLY A CA    1 
ATOM   7648  C  C     . GLY C 2 131 ? 399.539 357.185 266.680 1.00 128.75 ? 131 GLY A C     1 
ATOM   7649  O  O     . GLY C 2 131 ? 398.353 357.542 266.785 1.00 129.19 ? 131 GLY A O     1 
ATOM   7650  N  N     . LEU C 2 132 ? 400.534 357.648 267.440 1.00 115.43 ? 132 LEU A N     1 
ATOM   7651  C  CA    . LEU C 2 132 ? 400.259 358.585 268.562 1.00 114.49 ? 132 LEU A CA    1 
ATOM   7652  C  C     . LEU C 2 132 ? 400.369 360.022 268.053 1.00 116.51 ? 132 LEU A C     1 
ATOM   7653  O  O     . LEU C 2 132 ? 401.351 360.327 267.359 1.00 118.00 ? 132 LEU A O     1 
ATOM   7654  C  CB    . LEU C 2 132 ? 401.246 358.324 269.702 1.00 114.35 ? 132 LEU A CB    1 
ATOM   7655  C  CG    . LEU C 2 132 ? 401.017 359.148 270.967 1.00 116.61 ? 132 LEU A CG    1 
ATOM   7656  C  CD1   . LEU C 2 132 ? 399.637 358.876 271.545 1.00 115.85 ? 132 LEU A CD1   1 
ATOM   7657  C  CD2   . LEU C 2 132 ? 402.094 358.855 272.001 1.00 117.82 ? 132 LEU A CD2   1 
ATOM   7658  N  N     . GLN C 2 133 ? 399.388 360.860 268.390 1.00 120.61 ? 133 GLN A N     1 
ATOM   7659  C  CA    . GLN C 2 133 ? 399.391 362.270 267.928 1.00 116.05 ? 133 GLN A CA    1 
ATOM   7660  C  C     . GLN C 2 133 ? 399.892 363.152 269.070 1.00 116.97 ? 133 GLN A C     1 
ATOM   7661  O  O     . GLN C 2 133 ? 400.595 364.135 268.781 1.00 118.50 ? 133 GLN A O     1 
ATOM   7662  C  CB    . GLN C 2 133 ? 397.993 362.695 267.482 1.00 116.63 ? 133 GLN A CB    1 
ATOM   7663  C  CG    . GLN C 2 133 ? 397.484 361.967 266.245 1.00 121.82 ? 133 GLN A CG    1 
ATOM   7664  C  CD    . GLN C 2 133 ? 398.349 362.163 265.024 1.00 128.62 ? 133 GLN A CD    1 
ATOM   7665  O  OE1   . GLN C 2 133 ? 398.847 363.256 264.765 1.00 128.76 ? 133 GLN A OE1   1 
ATOM   7666  N  NE2   . GLN C 2 133 ? 398.540 361.100 264.260 1.00 128.02 ? 133 GLN A NE2   1 
ATOM   7667  N  N     . GLY C 2 134 ? 399.550 362.813 270.314 1.00 110.42 ? 134 GLY A N     1 
ATOM   7668  C  CA    . GLY C 2 134 ? 400.085 363.580 271.418 1.00 113.96 ? 134 GLY A CA    1 
ATOM   7669  C  C     . GLY C 2 134 ? 399.396 363.214 272.717 1.00 106.19 ? 134 GLY A C     1 
ATOM   7670  O  O     . GLY C 2 134 ? 398.667 362.223 272.799 1.00 112.72 ? 134 GLY A O     1 
ATOM   7671  N  N     . PHE C 2 135 ? 399.645 364.047 273.727 1.00 86.50  ? 135 PHE A N     1 
ATOM   7672  C  CA    . PHE C 2 135 ? 399.147 363.853 275.082 1.00 90.03  ? 135 PHE A CA    1 
ATOM   7673  C  C     . PHE C 2 135 ? 398.181 364.971 275.450 1.00 100.88 ? 135 PHE A C     1 
ATOM   7674  O  O     . PHE C 2 135 ? 398.393 366.130 275.084 1.00 113.52 ? 135 PHE A O     1 
ATOM   7675  C  CB    . PHE C 2 135 ? 400.299 363.823 276.089 1.00 92.74  ? 135 PHE A CB    1 
ATOM   7676  C  CG    . PHE C 2 135 ? 401.314 362.752 275.820 1.00 96.58  ? 135 PHE A CG    1 
ATOM   7677  C  CD1   . PHE C 2 135 ? 402.398 362.997 274.997 1.00 100.14 ? 135 PHE A CD1   1 
ATOM   7678  C  CD2   . PHE C 2 135 ? 401.188 361.501 276.397 1.00 97.53  ? 135 PHE A CD2   1 
ATOM   7679  C  CE1   . PHE C 2 135 ? 403.334 362.014 274.751 1.00 102.85 ? 135 PHE A CE1   1 
ATOM   7680  C  CE2   . PHE C 2 135 ? 402.122 360.515 276.154 1.00 94.10  ? 135 PHE A CE2   1 
ATOM   7681  C  CZ    . PHE C 2 135 ? 403.196 360.772 275.330 1.00 95.99  ? 135 PHE A CZ    1 
ATOM   7682  N  N     . LEU C 2 136 ? 397.122 364.608 276.177 1.00 108.99 ? 136 LEU A N     1 
ATOM   7683  C  CA    . LEU C 2 136 ? 396.142 365.547 276.721 1.00 104.29 ? 136 LEU A CA    1 
ATOM   7684  C  C     . LEU C 2 136 ? 396.248 365.504 278.240 1.00 111.35 ? 136 LEU A C     1 
ATOM   7685  O  O     . LEU C 2 136 ? 395.904 364.492 278.860 1.00 118.45 ? 136 LEU A O     1 
ATOM   7686  C  CB    . LEU C 2 136 ? 394.730 365.193 276.263 1.00 107.15 ? 136 LEU A CB    1 
ATOM   7687  C  CG    . LEU C 2 136 ? 394.219 365.915 275.016 1.00 108.47 ? 136 LEU A CG    1 
ATOM   7688  C  CD1   . LEU C 2 136 ? 394.893 365.369 273.771 1.00 116.27 ? 136 LEU A CD1   1 
ATOM   7689  C  CD2   . LEU C 2 136 ? 392.711 365.784 274.910 1.00 109.49 ? 136 LEU A CD2   1 
ATOM   7690  N  N     . VAL C 2 137 ? 396.709 366.605 278.833 1.00 100.72 ? 137 VAL A N     1 
ATOM   7691  C  CA    . VAL C 2 137 ? 396.969 366.703 280.265 1.00 94.31  ? 137 VAL A CA    1 
ATOM   7692  C  C     . VAL C 2 137 ? 395.920 367.610 280.892 1.00 92.46  ? 137 VAL A C     1 
ATOM   7693  O  O     . VAL C 2 137 ? 395.597 368.671 280.346 1.00 97.00  ? 137 VAL A O     1 
ATOM   7694  C  CB    . VAL C 2 137 ? 398.389 367.231 280.546 1.00 92.81  ? 137 VAL A CB    1 
ATOM   7695  C  CG1   . VAL C 2 137 ? 398.617 367.371 282.052 1.00 97.49  ? 137 VAL A CG1   1 
ATOM   7696  C  CG2   . VAL C 2 137 ? 399.437 366.313 279.915 1.00 94.00  ? 137 VAL A CG2   1 
ATOM   7697  N  N     . PHE C 2 138 ? 395.391 367.184 282.038 1.00 99.82  ? 138 PHE A N     1 
ATOM   7698  C  CA    . PHE C 2 138 ? 394.371 367.910 282.785 1.00 103.31 ? 138 PHE A CA    1 
ATOM   7699  C  C     . PHE C 2 138 ? 394.866 368.120 284.208 1.00 109.26 ? 138 PHE A C     1 
ATOM   7700  O  O     . PHE C 2 138 ? 395.251 367.159 284.881 1.00 114.01 ? 138 PHE A O     1 
ATOM   7701  C  CB    . PHE C 2 138 ? 393.047 367.142 282.798 1.00 102.30 ? 138 PHE A CB    1 
ATOM   7702  C  CG    . PHE C 2 138 ? 392.367 367.077 281.461 1.00 102.32 ? 138 PHE A CG    1 
ATOM   7703  C  CD1   . PHE C 2 138 ? 392.780 366.169 280.501 1.00 103.61 ? 138 PHE A CD1   1 
ATOM   7704  C  CD2   . PHE C 2 138 ? 391.309 367.917 281.168 1.00 103.65 ? 138 PHE A CD2   1 
ATOM   7705  C  CE1   . PHE C 2 138 ? 392.155 366.105 279.274 1.00 102.43 ? 138 PHE A CE1   1 
ATOM   7706  C  CE2   . PHE C 2 138 ? 390.680 367.857 279.941 1.00 104.71 ? 138 PHE A CE2   1 
ATOM   7707  C  CZ    . PHE C 2 138 ? 391.104 366.949 278.995 1.00 103.39 ? 138 PHE A CZ    1 
ATOM   7708  N  N     . HIS C 2 139 ? 394.850 369.366 284.665 1.00 104.53 ? 139 HIS A N     1 
ATOM   7709  C  CA    . HIS C 2 139 ? 395.361 369.713 285.988 1.00 104.00 ? 139 HIS A CA    1 
ATOM   7710  C  C     . HIS C 2 139 ? 394.888 371.122 286.319 1.00 103.80 ? 139 HIS A C     1 
ATOM   7711  O  O     . HIS C 2 139 ? 394.144 371.742 285.553 1.00 109.53 ? 139 HIS A O     1 
ATOM   7712  C  CB    . HIS C 2 139 ? 396.886 369.622 286.042 1.00 102.11 ? 139 HIS A CB    1 
ATOM   7713  C  CG    . HIS C 2 139 ? 397.578 370.686 285.252 1.00 100.97 ? 139 HIS A CG    1 
ATOM   7714  N  ND1   . HIS C 2 139 ? 398.451 371.586 285.823 1.00 106.13 ? 139 HIS A ND1   1 
ATOM   7715  C  CD2   . HIS C 2 139 ? 397.518 371.003 283.937 1.00 98.56  ? 139 HIS A CD2   1 
ATOM   7716  C  CE1   . HIS C 2 139 ? 398.906 372.406 284.893 1.00 103.80 ? 139 HIS A CE1   1 
ATOM   7717  N  NE2   . HIS C 2 139 ? 398.356 372.073 283.739 1.00 100.71 ? 139 HIS A NE2   1 
ATOM   7718  N  N     . SER C 2 140 ? 395.320 371.617 287.479 1.00 97.08  ? 140 SER A N     1 
ATOM   7719  C  CA    . SER C 2 140 ? 395.043 372.973 287.932 1.00 98.12  ? 140 SER A CA    1 
ATOM   7720  C  C     . SER C 2 140 ? 396.317 373.576 288.499 1.00 96.03  ? 140 SER A C     1 
ATOM   7721  O  O     . SER C 2 140 ? 397.134 372.870 289.096 1.00 100.40 ? 140 SER A O     1 
ATOM   7722  C  CB    . SER C 2 140 ? 393.941 372.993 288.993 1.00 101.29 ? 140 SER A CB    1 
ATOM   7723  O  OG    . SER C 2 140 ? 394.379 372.376 290.189 1.00 105.83 ? 140 SER A OG    1 
ATOM   7724  N  N     . PHE C 2 141 ? 396.486 374.886 288.308 1.00 94.84  ? 141 PHE A N     1 
ATOM   7725  C  CA    . PHE C 2 141 ? 397.692 375.546 288.797 1.00 100.79 ? 141 PHE A CA    1 
ATOM   7726  C  C     . PHE C 2 141 ? 397.693 375.678 290.313 1.00 103.00 ? 141 PHE A C     1 
ATOM   7727  O  O     . PHE C 2 141 ? 398.752 375.573 290.940 1.00 103.84 ? 141 PHE A O     1 
ATOM   7728  C  CB    . PHE C 2 141 ? 397.831 376.938 288.179 1.00 106.20 ? 141 PHE A CB    1 
ATOM   7729  C  CG    . PHE C 2 141 ? 398.013 376.948 286.683 1.00 105.56 ? 141 PHE A CG    1 
ATOM   7730  C  CD1   . PHE C 2 141 ? 398.969 376.163 286.062 1.00 104.73 ? 141 PHE A CD1   1 
ATOM   7731  C  CD2   . PHE C 2 141 ? 397.244 377.788 285.902 1.00 105.48 ? 141 PHE A CD2   1 
ATOM   7732  C  CE1   . PHE C 2 141 ? 399.131 376.196 284.694 1.00 101.45 ? 141 PHE A CE1   1 
ATOM   7733  C  CE2   . PHE C 2 141 ? 397.405 377.826 284.541 1.00 102.46 ? 141 PHE A CE2   1 
ATOM   7734  C  CZ    . PHE C 2 141 ? 398.351 377.031 283.934 1.00 101.17 ? 141 PHE A CZ    1 
ATOM   7735  N  N     . GLY C 2 142 ? 396.529 375.928 290.914 1.00 105.41 ? 142 GLY A N     1 
ATOM   7736  C  CA    . GLY C 2 142 ? 396.475 376.130 292.351 1.00 105.65 ? 142 GLY A CA    1 
ATOM   7737  C  C     . GLY C 2 142 ? 396.842 374.896 293.148 1.00 104.80 ? 142 GLY A C     1 
ATOM   7738  O  O     . GLY C 2 142 ? 397.406 375.005 294.240 1.00 107.65 ? 142 GLY A O     1 
ATOM   7739  N  N     . GLY C 2 143 ? 396.534 373.714 292.623 1.00 107.17 ? 143 GLY A N     1 
ATOM   7740  C  CA    . GLY C 2 143 ? 396.812 372.497 293.347 1.00 104.42 ? 143 GLY A CA    1 
ATOM   7741  C  C     . GLY C 2 143 ? 398.288 372.153 293.372 1.00 105.73 ? 143 GLY A C     1 
ATOM   7742  O  O     . GLY C 2 143 ? 399.027 372.375 292.419 1.00 106.13 ? 143 GLY A O     1 
ATOM   7743  N  N     . GLY C 2 144 ? 398.710 371.554 294.479 1.00 109.36 ? 144 GLY A N     1 
ATOM   7744  C  CA    . GLY C 2 144 ? 400.104 371.203 294.650 1.00 104.48 ? 144 GLY A CA    1 
ATOM   7745  C  C     . GLY C 2 144 ? 400.466 369.993 293.824 1.00 96.22  ? 144 GLY A C     1 
ATOM   7746  O  O     . GLY C 2 144 ? 401.435 370.030 293.059 1.00 91.73  ? 144 GLY A O     1 
ATOM   7747  N  N     . THR C 2 145 ? 399.679 368.921 293.982 1.00 113.81 ? 145 THR A N     1 
ATOM   7748  C  CA    . THR C 2 145 ? 399.839 367.732 293.151 1.00 115.04 ? 145 THR A CA    1 
ATOM   7749  C  C     . THR C 2 145 ? 399.760 368.090 291.679 1.00 108.88 ? 145 THR A C     1 
ATOM   7750  O  O     . THR C 2 145 ? 400.676 367.782 290.909 1.00 114.52 ? 145 THR A O     1 
ATOM   7751  C  CB    . THR C 2 145 ? 398.764 366.698 293.497 1.00 118.28 ? 145 THR A CB    1 
ATOM   7752  O  OG1   . THR C 2 145 ? 398.965 366.214 294.830 1.00 125.60 ? 145 THR A OG1   1 
ATOM   7753  C  CG2   . THR C 2 145 ? 398.781 365.532 292.512 1.00 111.65 ? 145 THR A CG2   1 
ATOM   7754  N  N     . GLY C 2 146 ? 398.693 368.791 291.292 1.00 106.24 ? 146 GLY A N     1 
ATOM   7755  C  CA    . GLY C 2 146 ? 398.480 369.236 289.931 1.00 107.82 ? 146 GLY A CA    1 
ATOM   7756  C  C     . GLY C 2 146 ? 399.654 370.003 289.370 1.00 105.79 ? 146 GLY A C     1 
ATOM   7757  O  O     . GLY C 2 146 ? 400.300 369.523 288.440 1.00 111.64 ? 146 GLY A O     1 
ATOM   7758  N  N     . SER C 2 147 ? 399.996 371.136 289.985 1.00 111.34 ? 147 SER A N     1 
ATOM   7759  C  CA    . SER C 2 147 ? 401.043 371.998 289.445 1.00 112.64 ? 147 SER A CA    1 
ATOM   7760  C  C     . SER C 2 147 ? 402.405 371.308 289.449 1.00 110.82 ? 147 SER A C     1 
ATOM   7761  O  O     . SER C 2 147 ? 403.066 371.215 288.405 1.00 111.81 ? 147 SER A O     1 
ATOM   7762  C  CB    . SER C 2 147 ? 401.095 373.292 290.255 1.00 113.14 ? 147 SER A CB    1 
ATOM   7763  O  OG    . SER C 2 147 ? 401.906 373.136 291.404 1.00 117.87 ? 147 SER A OG    1 
ATOM   7764  N  N     . GLY C 2 148 ? 402.832 370.791 290.605 1.00 109.94 ? 148 GLY A N     1 
ATOM   7765  C  CA    . GLY C 2 148 ? 404.172 370.235 290.699 1.00 106.31 ? 148 GLY A CA    1 
ATOM   7766  C  C     . GLY C 2 148 ? 404.353 368.982 289.865 1.00 103.49 ? 148 GLY A C     1 
ATOM   7767  O  O     . GLY C 2 148 ? 405.313 368.870 289.090 1.00 109.85 ? 148 GLY A O     1 
ATOM   7768  N  N     . PHE C 2 149 ? 403.437 368.018 290.004 1.00 100.36 ? 149 PHE A N     1 
ATOM   7769  C  CA    . PHE C 2 149 ? 403.597 366.792 289.248 1.00 98.66  ? 149 PHE A CA    1 
ATOM   7770  C  C     . PHE C 2 149 ? 403.342 367.011 287.768 1.00 100.50 ? 149 PHE A C     1 
ATOM   7771  O  O     . PHE C 2 149 ? 403.931 366.310 286.944 1.00 109.31 ? 149 PHE A O     1 
ATOM   7772  C  CB    . PHE C 2 149 ? 402.679 365.701 289.786 1.00 101.25 ? 149 PHE A CB    1 
ATOM   7773  C  CG    . PHE C 2 149 ? 403.129 364.326 289.418 1.00 102.78 ? 149 PHE A CG    1 
ATOM   7774  C  CD1   . PHE C 2 149 ? 404.169 363.725 290.100 1.00 103.02 ? 149 PHE A CD1   1 
ATOM   7775  C  CD2   . PHE C 2 149 ? 402.538 363.648 288.369 1.00 103.57 ? 149 PHE A CD2   1 
ATOM   7776  C  CE1   . PHE C 2 149 ? 404.601 362.469 289.754 1.00 107.92 ? 149 PHE A CE1   1 
ATOM   7777  C  CE2   . PHE C 2 149 ? 402.967 362.388 288.020 1.00 105.76 ? 149 PHE A CE2   1 
ATOM   7778  C  CZ    . PHE C 2 149 ? 403.999 361.797 288.716 1.00 107.93 ? 149 PHE A CZ    1 
ATOM   7779  N  N     . THR C 2 150 ? 402.500 367.981 287.394 1.00 103.22 ? 150 THR A N     1 
ATOM   7780  C  CA    . THR C 2 150 ? 402.347 368.283 285.980 1.00 103.49 ? 150 THR A CA    1 
ATOM   7781  C  C     . THR C 2 150 ? 403.626 368.868 285.411 1.00 103.89 ? 150 THR A C     1 
ATOM   7782  O  O     . THR C 2 150 ? 404.006 368.536 284.290 1.00 106.80 ? 150 THR A O     1 
ATOM   7783  C  CB    . THR C 2 150 ? 401.181 369.244 285.755 1.00 110.64 ? 150 THR A CB    1 
ATOM   7784  O  OG1   . THR C 2 150 ? 399.969 368.659 286.248 1.00 119.19 ? 150 THR A OG1   1 
ATOM   7785  C  CG2   . THR C 2 150 ? 401.026 369.545 284.271 1.00 108.17 ? 150 THR A CG2   1 
ATOM   7786  N  N     . SER C 2 151 ? 404.311 369.730 286.167 1.00 110.58 ? 151 SER A N     1 
ATOM   7787  C  CA    . SER C 2 151 ? 405.585 370.265 285.692 1.00 110.91 ? 151 SER A CA    1 
ATOM   7788  C  C     . SER C 2 151 ? 406.621 369.157 285.529 1.00 107.44 ? 151 SER A C     1 
ATOM   7789  O  O     . SER C 2 151 ? 407.320 369.085 284.506 1.00 112.56 ? 151 SER A O     1 
ATOM   7790  C  CB    . SER C 2 151 ? 406.091 371.334 286.657 1.00 114.88 ? 151 SER A CB    1 
ATOM   7791  O  OG    . SER C 2 151 ? 405.337 372.526 286.531 1.00 120.26 ? 151 SER A OG    1 
ATOM   7792  N  N     . LEU C 2 152 ? 406.716 368.270 286.526 1.00 100.19 ? 152 LEU A N     1 
ATOM   7793  C  CA    . LEU C 2 152 ? 407.670 367.164 286.458 1.00 96.10  ? 152 LEU A CA    1 
ATOM   7794  C  C     . LEU C 2 152 ? 407.357 366.247 285.280 1.00 99.83  ? 152 LEU A C     1 
ATOM   7795  O  O     . LEU C 2 152 ? 408.244 365.897 284.486 1.00 107.74 ? 152 LEU A O     1 
ATOM   7796  C  CB    . LEU C 2 152 ? 407.645 366.379 287.771 1.00 96.69  ? 152 LEU A CB    1 
ATOM   7797  C  CG    . LEU C 2 152 ? 408.616 365.204 287.934 1.00 95.39  ? 152 LEU A CG    1 
ATOM   7798  C  CD1   . LEU C 2 152 ? 410.055 365.691 287.955 1.00 101.92 ? 152 LEU A CD1   1 
ATOM   7799  C  CD2   . LEU C 2 152 ? 408.292 364.428 289.196 1.00 103.96 ? 152 LEU A CD2   1 
ATOM   7800  N  N     . LEU C 2 153 ? 406.088 365.863 285.147 1.00 105.81 ? 153 LEU A N     1 
ATOM   7801  C  CA    . LEU C 2 153 ? 405.669 364.977 284.073 1.00 105.32 ? 153 LEU A CA    1 
ATOM   7802  C  C     . LEU C 2 153 ? 405.864 365.635 282.718 1.00 103.14 ? 153 LEU A C     1 
ATOM   7803  O  O     . LEU C 2 153 ? 406.224 364.968 281.747 1.00 109.53 ? 153 LEU A O     1 
ATOM   7804  C  CB    . LEU C 2 153 ? 404.207 364.590 284.286 1.00 106.01 ? 153 LEU A CB    1 
ATOM   7805  C  CG    . LEU C 2 153 ? 403.561 363.590 283.330 1.00 105.79 ? 153 LEU A CG    1 
ATOM   7806  C  CD1   . LEU C 2 153 ? 403.918 362.186 283.756 1.00 111.13 ? 153 LEU A CD1   1 
ATOM   7807  C  CD2   . LEU C 2 153 ? 402.061 363.779 283.300 1.00 106.10 ? 153 LEU A CD2   1 
ATOM   7808  N  N     . MET C 2 154 ? 405.614 366.941 282.628 1.00 109.01 ? 154 MET A N     1 
ATOM   7809  C  CA    . MET C 2 154 ? 405.768 367.637 281.358 1.00 110.00 ? 154 MET A CA    1 
ATOM   7810  C  C     . MET C 2 154 ? 407.222 367.676 280.925 1.00 110.57 ? 154 MET A C     1 
ATOM   7811  O  O     . MET C 2 154 ? 407.523 367.454 279.750 1.00 118.85 ? 154 MET A O     1 
ATOM   7812  C  CB    . MET C 2 154 ? 405.198 369.051 281.459 1.00 110.95 ? 154 MET A CB    1 
ATOM   7813  C  CG    . MET C 2 154 ? 403.676 369.107 281.294 1.00 110.80 ? 154 MET A CG    1 
ATOM   7814  S  SD    . MET C 2 154 ? 402.953 368.801 279.656 1.00 117.68 ? 154 MET A SD    1 
ATOM   7815  C  CE    . MET C 2 154 ? 404.319 368.958 278.507 1.00 112.91 ? 154 MET A CE    1 
ATOM   7816  N  N     . GLU C 2 155 ? 408.145 367.943 281.855 1.00 110.78 ? 155 GLU A N     1 
ATOM   7817  C  CA    . GLU C 2 155 ? 409.551 367.937 281.459 1.00 108.59 ? 155 GLU A CA    1 
ATOM   7818  C  C     . GLU C 2 155 ? 410.013 366.529 281.089 1.00 109.22 ? 155 GLU A C     1 
ATOM   7819  O  O     . GLU C 2 155 ? 410.756 366.353 280.112 1.00 115.72 ? 155 GLU A O     1 
ATOM   7820  C  CB    . GLU C 2 155 ? 410.428 368.556 282.555 1.00 111.15 ? 155 GLU A CB    1 
ATOM   7821  C  CG    . GLU C 2 155 ? 410.459 367.857 283.904 1.00 114.49 ? 155 GLU A CG    1 
ATOM   7822  C  CD    . GLU C 2 155 ? 411.591 368.351 284.781 1.00 117.34 ? 155 GLU A CD    1 
ATOM   7823  O  OE1   . GLU C 2 155 ? 411.810 369.579 284.834 1.00 118.64 ? 155 GLU A OE1   1 
ATOM   7824  O  OE2   . GLU C 2 155 ? 412.263 367.511 285.415 1.00 115.46 ? 155 GLU A OE2   1 
ATOM   7825  N  N     . ARG C 2 156 ? 409.555 365.509 281.824 1.00 108.06 ? 156 ARG A N     1 
ATOM   7826  C  CA    . ARG C 2 156 ? 409.945 364.141 281.490 1.00 108.63 ? 156 ARG A CA    1 
ATOM   7827  C  C     . ARG C 2 156 ? 409.389 363.720 280.134 1.00 111.98 ? 156 ARG A C     1 
ATOM   7828  O  O     . ARG C 2 156 ? 410.098 363.106 279.325 1.00 111.97 ? 156 ARG A O     1 
ATOM   7829  C  CB    . ARG C 2 156 ? 409.477 363.178 282.581 1.00 108.03 ? 156 ARG A CB    1 
ATOM   7830  C  CG    . ARG C 2 156 ? 410.192 363.341 283.917 1.00 108.53 ? 156 ARG A CG    1 
ATOM   7831  C  CD    . ARG C 2 156 ? 411.635 362.864 283.871 1.00 107.75 ? 156 ARG A CD    1 
ATOM   7832  N  NE    . ARG C 2 156 ? 412.208 362.754 285.211 1.00 112.60 ? 156 ARG A NE    1 
ATOM   7833  C  CZ    . ARG C 2 156 ? 412.243 361.658 285.964 1.00 116.81 ? 156 ARG A CZ    1 
ATOM   7834  N  NH1   . ARG C 2 156 ? 411.737 360.503 285.555 1.00 110.81 ? 156 ARG A NH1   1 
ATOM   7835  N  NH2   . ARG C 2 156 ? 412.799 361.723 287.170 1.00 118.67 ? 156 ARG A NH2   1 
ATOM   7836  N  N     . LEU C 2 157 ? 408.126 364.051 279.861 1.00 110.99 ? 157 LEU A N     1 
ATOM   7837  C  CA    . LEU C 2 157 ? 407.531 363.704 278.578 1.00 103.80 ? 157 LEU A CA    1 
ATOM   7838  C  C     . LEU C 2 157 ? 408.149 364.510 277.449 1.00 110.36 ? 157 LEU A C     1 
ATOM   7839  O  O     . LEU C 2 157 ? 408.244 364.019 276.326 1.00 119.08 ? 157 LEU A O     1 
ATOM   7840  C  CB    . LEU C 2 157 ? 406.018 363.916 278.611 1.00 104.82 ? 157 LEU A CB    1 
ATOM   7841  C  CG    . LEU C 2 157 ? 405.192 362.957 279.468 1.00 107.40 ? 157 LEU A CG    1 
ATOM   7842  C  CD1   . LEU C 2 157 ? 403.774 363.483 279.612 1.00 111.93 ? 157 LEU A CD1   1 
ATOM   7843  C  CD2   . LEU C 2 157 ? 405.184 361.554 278.880 1.00 115.20 ? 157 LEU A CD2   1 
ATOM   7844  N  N     . SER C 2 158 ? 408.566 365.748 277.713 1.00 124.41 ? 158 SER A N     1 
ATOM   7845  C  CA    . SER C 2 158 ? 409.281 366.498 276.689 1.00 124.76 ? 158 SER A CA    1 
ATOM   7846  C  C     . SER C 2 158 ? 410.596 365.816 276.348 1.00 124.77 ? 158 SER A C     1 
ATOM   7847  O  O     . SER C 2 158 ? 410.925 365.648 275.168 1.00 124.98 ? 158 SER A O     1 
ATOM   7848  C  CB    . SER C 2 158 ? 409.521 367.932 277.156 1.00 129.64 ? 158 SER A CB    1 
ATOM   7849  O  OG    . SER C 2 158 ? 410.067 368.717 276.112 1.00 126.03 ? 158 SER A OG    1 
ATOM   7850  N  N     . VAL C 2 159 ? 411.324 365.358 277.372 1.00 122.16 ? 159 VAL A N     1 
ATOM   7851  C  CA    . VAL C 2 159 ? 412.590 364.664 277.145 1.00 119.48 ? 159 VAL A CA    1 
ATOM   7852  C  C     . VAL C 2 159 ? 412.364 363.378 276.356 1.00 119.23 ? 159 VAL A C     1 
ATOM   7853  O  O     . VAL C 2 159 ? 413.130 363.054 275.441 1.00 122.10 ? 159 VAL A O     1 
ATOM   7854  C  CB    . VAL C 2 159 ? 413.293 364.394 278.492 1.00 118.90 ? 159 VAL A CB    1 
ATOM   7855  C  CG1   . VAL C 2 159 ? 414.442 363.391 278.338 1.00 114.96 ? 159 VAL A CG1   1 
ATOM   7856  C  CG2   . VAL C 2 159 ? 413.813 365.696 279.091 1.00 117.32 ? 159 VAL A CG2   1 
ATOM   7857  N  N     . ASP C 2 160 ? 411.311 362.629 276.691 1.00 122.62 ? 160 ASP A N     1 
ATOM   7858  C  CA    . ASP C 2 160 ? 411.085 361.337 276.044 1.00 123.69 ? 160 ASP A CA    1 
ATOM   7859  C  C     . ASP C 2 160 ? 410.414 361.491 274.680 1.00 121.09 ? 160 ASP A C     1 
ATOM   7860  O  O     . ASP C 2 160 ? 411.001 361.157 273.646 1.00 121.74 ? 160 ASP A O     1 
ATOM   7861  C  CB    . ASP C 2 160 ? 410.239 360.444 276.955 1.00 124.63 ? 160 ASP A CB    1 
ATOM   7862  C  CG    . ASP C 2 160 ? 411.011 359.943 278.158 1.00 127.31 ? 160 ASP A CG    1 
ATOM   7863  O  OD1   . ASP C 2 160 ? 412.081 360.513 278.458 1.00 125.31 ? 160 ASP A OD1   1 
ATOM   7864  O  OD2   . ASP C 2 160 ? 410.549 358.980 278.804 1.00 126.61 ? 160 ASP A OD2   1 
ATOM   7865  N  N     . TYR C 2 161 ? 409.182 361.997 274.667 1.00 122.35 ? 161 TYR A N     1 
ATOM   7866  C  CA    . TYR C 2 161 ? 408.342 362.148 273.481 1.00 118.07 ? 161 TYR A CA    1 
ATOM   7867  C  C     . TYR C 2 161 ? 408.249 363.602 273.033 1.00 126.10 ? 161 TYR A C     1 
ATOM   7868  O  O     . TYR C 2 161 ? 407.164 364.059 272.665 1.00 128.65 ? 161 TYR A O     1 
ATOM   7869  C  CB    . TYR C 2 161 ? 406.940 361.606 273.756 1.00 120.09 ? 161 TYR A CB    1 
ATOM   7870  C  CG    . TYR C 2 161 ? 406.877 360.175 274.233 1.00 118.69 ? 161 TYR A CG    1 
ATOM   7871  C  CD1   . TYR C 2 161 ? 407.014 359.862 275.579 1.00 119.29 ? 161 TYR A CD1   1 
ATOM   7872  C  CD2   . TYR C 2 161 ? 406.659 359.140 273.340 1.00 124.19 ? 161 TYR A CD2   1 
ATOM   7873  C  CE1   . TYR C 2 161 ? 406.950 358.559 276.016 1.00 120.77 ? 161 TYR A CE1   1 
ATOM   7874  C  CE2   . TYR C 2 161 ? 406.592 357.834 273.768 1.00 127.91 ? 161 TYR A CE2   1 
ATOM   7875  C  CZ    . TYR C 2 161 ? 406.737 357.549 275.106 1.00 126.12 ? 161 TYR A CZ    1 
ATOM   7876  O  OH    . TYR C 2 161 ? 406.671 356.246 275.533 1.00 127.10 ? 161 TYR A OH    1 
ATOM   7877  N  N     . GLY C 2 162 ? 409.348 364.365 273.061 1.00 141.62 ? 162 GLY A N     1 
ATOM   7878  C  CA    . GLY C 2 162 ? 409.284 365.781 272.718 1.00 140.12 ? 162 GLY A CA    1 
ATOM   7879  C  C     . GLY C 2 162 ? 408.851 366.083 271.294 1.00 137.65 ? 162 GLY A C     1 
ATOM   7880  O  O     . GLY C 2 162 ? 408.490 367.226 270.996 1.00 136.64 ? 162 GLY A O     1 
ATOM   7881  N  N     . LYS C 2 163 ? 408.878 365.088 270.407 1.00 132.98 ? 163 LYS A N     1 
ATOM   7882  C  CA    . LYS C 2 163 ? 408.487 365.312 269.022 1.00 131.64 ? 163 LYS A CA    1 
ATOM   7883  C  C     . LYS C 2 163 ? 406.981 365.519 268.902 1.00 130.84 ? 163 LYS A C     1 
ATOM   7884  O  O     . LYS C 2 163 ? 406.525 366.327 268.084 1.00 131.51 ? 163 LYS A O     1 
ATOM   7885  C  CB    . LYS C 2 163 ? 408.927 364.138 268.134 1.00 130.12 ? 163 LYS A CB    1 
ATOM   7886  C  CG    . LYS C 2 163 ? 410.457 363.889 267.930 1.00 133.20 ? 163 LYS A CG    1 
ATOM   7887  C  CD    . LYS C 2 163 ? 411.330 363.651 269.183 1.00 134.91 ? 163 LYS A CD    1 
ATOM   7888  C  CE    . LYS C 2 163 ? 410.916 362.415 269.990 1.00 134.72 ? 163 LYS A CE    1 
ATOM   7889  N  NZ    . LYS C 2 163 ? 411.558 362.393 271.336 1.00 134.08 ? 163 LYS A NZ    1 
ATOM   7890  N  N     . LYS C 2 164 ? 406.198 364.807 269.707 1.00 113.42 ? 164 LYS A N     1 
ATOM   7891  C  CA    . LYS C 2 164 ? 404.750 364.780 269.571 1.00 110.83 ? 164 LYS A CA    1 
ATOM   7892  C  C     . LYS C 2 164 ? 404.099 365.923 270.348 1.00 113.13 ? 164 LYS A C     1 
ATOM   7893  O  O     . LYS C 2 164 ? 404.718 366.577 271.189 1.00 112.71 ? 164 LYS A O     1 
ATOM   7894  C  CB    . LYS C 2 164 ? 404.210 363.431 270.043 1.00 110.36 ? 164 LYS A CB    1 
ATOM   7895  C  CG    . LYS C 2 164 ? 404.725 362.262 269.220 1.00 114.14 ? 164 LYS A CG    1 
ATOM   7896  C  CD    . LYS C 2 164 ? 404.069 360.955 269.616 1.00 114.99 ? 164 LYS A CD    1 
ATOM   7897  C  CE    . LYS C 2 164 ? 404.491 359.827 268.689 1.00 114.10 ? 164 LYS A CE    1 
ATOM   7898  N  NZ    . LYS C 2 164 ? 403.890 359.955 267.333 1.00 111.18 ? 164 LYS A NZ    1 
ATOM   7899  N  N     . SER C 2 165 ? 402.824 366.158 270.049 1.00 119.00 ? 165 SER A N     1 
ATOM   7900  C  CA    . SER C 2 165 ? 402.086 367.256 270.660 1.00 120.22 ? 165 SER A CA    1 
ATOM   7901  C  C     . SER C 2 165 ? 401.824 366.985 272.137 1.00 119.88 ? 165 SER A C     1 
ATOM   7902  O  O     . SER C 2 165 ? 401.708 365.836 272.571 1.00 120.78 ? 165 SER A O     1 
ATOM   7903  C  CB    . SER C 2 165 ? 400.758 367.470 269.934 1.00 120.10 ? 165 SER A CB    1 
ATOM   7904  O  OG    . SER C 2 165 ? 400.946 367.555 268.533 1.00 117.47 ? 165 SER A OG    1 
ATOM   7905  N  N     . LYS C 2 166 ? 401.745 368.065 272.914 1.00 111.12 ? 166 LYS A N     1 
ATOM   7906  C  CA    . LYS C 2 166 ? 401.409 368.009 274.335 1.00 108.76 ? 166 LYS A CA    1 
ATOM   7907  C  C     . LYS C 2 166 ? 400.480 369.169 274.646 1.00 105.97 ? 166 LYS A C     1 
ATOM   7908  O  O     . LYS C 2 166 ? 400.889 370.329 274.543 1.00 110.13 ? 166 LYS A O     1 
ATOM   7909  C  CB    . LYS C 2 166 ? 402.658 368.088 275.217 1.00 107.94 ? 166 LYS A CB    1 
ATOM   7910  C  CG    . LYS C 2 166 ? 403.613 366.892 275.125 1.00 109.91 ? 166 LYS A CG    1 
ATOM   7911  C  CD    . LYS C 2 166 ? 405.079 367.296 275.254 1.00 111.80 ? 166 LYS A CD    1 
ATOM   7912  C  CE    . LYS C 2 166 ? 405.707 367.526 273.892 1.00 110.89 ? 166 LYS A CE    1 
ATOM   7913  N  NZ    . LYS C 2 166 ? 406.934 368.363 273.974 1.00 111.54 ? 166 LYS A NZ    1 
ATOM   7914  N  N     . LEU C 2 167 ? 399.246 368.858 275.044 1.00 109.23 ? 167 LEU A N     1 
ATOM   7915  C  CA    . LEU C 2 167 ? 398.182 369.844 275.210 1.00 107.60 ? 167 LEU A CA    1 
ATOM   7916  C  C     . LEU C 2 167 ? 397.680 369.784 276.644 1.00 108.04 ? 167 LEU A C     1 
ATOM   7917  O  O     . LEU C 2 167 ? 397.150 368.754 277.075 1.00 114.48 ? 167 LEU A O     1 
ATOM   7918  C  CB    . LEU C 2 167 ? 397.027 369.590 274.236 1.00 112.36 ? 167 LEU A CB    1 
ATOM   7919  C  CG    . LEU C 2 167 ? 397.216 369.813 272.726 1.00 110.21 ? 167 LEU A CG    1 
ATOM   7920  C  CD1   . LEU C 2 167 ? 397.491 371.275 272.429 1.00 114.49 ? 167 LEU A CD1   1 
ATOM   7921  C  CD2   . LEU C 2 167 ? 398.292 368.931 272.103 1.00 109.08 ? 167 LEU A CD2   1 
ATOM   7922  N  N     . GLU C 2 168 ? 397.839 370.886 277.373 1.00 111.85 ? 168 GLU A N     1 
ATOM   7923  C  CA    . GLU C 2 168 ? 397.382 371.003 278.751 1.00 110.32 ? 168 GLU A CA    1 
ATOM   7924  C  C     . GLU C 2 168 ? 396.016 371.667 278.795 1.00 106.21 ? 168 GLU A C     1 
ATOM   7925  O  O     . GLU C 2 168 ? 395.734 372.582 278.018 1.00 112.66 ? 168 GLU A O     1 
ATOM   7926  C  CB    . GLU C 2 168 ? 398.371 371.808 279.597 1.00 114.28 ? 168 GLU A CB    1 
ATOM   7927  C  CG    . GLU C 2 168 ? 399.695 371.108 279.844 1.00 122.48 ? 168 GLU A CG    1 
ATOM   7928  C  CD    . GLU C 2 168 ? 400.671 371.264 278.705 1.00 128.09 ? 168 GLU A CD    1 
ATOM   7929  O  OE1   . GLU C 2 168 ? 400.286 371.009 277.545 1.00 131.58 ? 168 GLU A OE1   1 
ATOM   7930  O  OE2   . GLU C 2 168 ? 401.832 371.621 278.975 1.00 126.70 ? 168 GLU A OE2   1 
ATOM   7931  N  N     . PHE C 2 169 ? 395.167 371.182 279.695 1.00 104.82 ? 169 PHE A N     1 
ATOM   7932  C  CA    . PHE C 2 169 ? 393.886 371.805 280.018 1.00 114.09 ? 169 PHE A CA    1 
ATOM   7933  C  C     . PHE C 2 169 ? 393.980 372.225 281.480 1.00 117.31 ? 169 PHE A C     1 
ATOM   7934  O  O     . PHE C 2 169 ? 393.600 371.482 282.388 1.00 116.53 ? 169 PHE A O     1 
ATOM   7935  C  CB    . PHE C 2 169 ? 392.723 370.861 279.752 1.00 116.82 ? 169 PHE A CB    1 
ATOM   7936  C  CG    . PHE C 2 169 ? 391.957 371.210 278.524 1.00 116.98 ? 169 PHE A CG    1 
ATOM   7937  C  CD1   . PHE C 2 169 ? 390.996 372.201 278.559 1.00 118.15 ? 169 PHE A CD1   1 
ATOM   7938  C  CD2   . PHE C 2 169 ? 392.209 370.564 277.329 1.00 116.58 ? 169 PHE A CD2   1 
ATOM   7939  C  CE1   . PHE C 2 169 ? 390.295 372.535 277.430 1.00 124.86 ? 169 PHE A CE1   1 
ATOM   7940  C  CE2   . PHE C 2 169 ? 391.506 370.892 276.197 1.00 118.37 ? 169 PHE A CE2   1 
ATOM   7941  C  CZ    . PHE C 2 169 ? 390.556 371.887 276.247 1.00 122.58 ? 169 PHE A CZ    1 
ATOM   7942  N  N     . SER C 2 170 ? 394.506 373.425 281.695 1.00 110.01 ? 170 SER A N     1 
ATOM   7943  C  CA    . SER C 2 170 ? 394.796 373.940 283.022 1.00 104.37 ? 170 SER A CA    1 
ATOM   7944  C  C     . SER C 2 170 ? 393.686 374.874 283.478 1.00 104.54 ? 170 SER A C     1 
ATOM   7945  O  O     . SER C 2 170 ? 393.092 375.601 282.678 1.00 113.99 ? 170 SER A O     1 
ATOM   7946  C  CB    . SER C 2 170 ? 396.132 374.680 283.037 1.00 107.88 ? 170 SER A CB    1 
ATOM   7947  O  OG    . SER C 2 170 ? 397.121 373.953 282.329 1.00 114.19 ? 170 SER A OG    1 
ATOM   7948  N  N     . ILE C 2 171 ? 393.417 374.843 284.777 1.00 94.42  ? 171 ILE A N     1 
ATOM   7949  C  CA    . ILE C 2 171 ? 392.450 375.726 285.413 1.00 93.30  ? 171 ILE A CA    1 
ATOM   7950  C  C     . ILE C 2 171 ? 393.229 376.940 285.893 1.00 99.00  ? 171 ILE A C     1 
ATOM   7951  O  O     . ILE C 2 171 ? 394.017 376.852 286.840 1.00 102.04 ? 171 ILE A O     1 
ATOM   7952  C  CB    . ILE C 2 171 ? 391.715 375.026 286.562 1.00 92.77  ? 171 ILE A CB    1 
ATOM   7953  C  CG1   . ILE C 2 171 ? 391.300 373.621 286.105 1.00 92.27  ? 171 ILE A CG1   1 
ATOM   7954  C  CG2   . ILE C 2 171 ? 390.496 375.857 287.015 1.00 96.96  ? 171 ILE A CG2   1 
ATOM   7955  C  CD1   . ILE C 2 171 ? 390.184 372.975 286.880 1.00 94.42  ? 171 ILE A CD1   1 
ATOM   7956  N  N     . TYR C 2 172 ? 393.013 378.065 285.228 1.00 119.67 ? 172 TYR A N     1 
ATOM   7957  C  CA    . TYR C 2 172 ? 393.696 379.291 285.601 1.00 116.78 ? 172 TYR A CA    1 
ATOM   7958  C  C     . TYR C 2 172 ? 393.248 379.733 286.996 1.00 117.57 ? 172 TYR A C     1 
ATOM   7959  O  O     . TYR C 2 172 ? 392.081 379.543 287.354 1.00 120.49 ? 172 TYR A O     1 
ATOM   7960  C  CB    . TYR C 2 172 ? 393.386 380.401 284.591 1.00 114.14 ? 172 TYR A CB    1 
ATOM   7961  C  CG    . TYR C 2 172 ? 394.460 381.452 284.403 1.00 115.37 ? 172 TYR A CG    1 
ATOM   7962  C  CD1   . TYR C 2 172 ? 395.771 381.119 284.066 1.00 118.01 ? 172 TYR A CD1   1 
ATOM   7963  C  CD2   . TYR C 2 172 ? 394.162 382.790 284.601 1.00 117.07 ? 172 TYR A CD2   1 
ATOM   7964  C  CE1   . TYR C 2 172 ? 396.735 382.093 283.913 1.00 120.57 ? 172 TYR A CE1   1 
ATOM   7965  C  CE2   . TYR C 2 172 ? 395.116 383.757 284.453 1.00 119.13 ? 172 TYR A CE2   1 
ATOM   7966  C  CZ    . TYR C 2 172 ? 396.396 383.409 284.111 1.00 121.82 ? 172 TYR A CZ    1 
ATOM   7967  O  OH    . TYR C 2 172 ? 397.331 384.404 283.968 1.00 122.34 ? 172 TYR A OH    1 
ATOM   7968  N  N     . PRO C 2 173 ? 394.133 380.318 287.811 1.00 100.79 ? 173 PRO A N     1 
ATOM   7969  C  CA    . PRO C 2 173 ? 393.654 380.925 289.059 1.00 101.60 ? 173 PRO A CA    1 
ATOM   7970  C  C     . PRO C 2 173 ? 392.758 382.120 288.768 1.00 102.86 ? 173 PRO A C     1 
ATOM   7971  O  O     . PRO C 2 173 ? 393.132 383.031 288.027 1.00 105.18 ? 173 PRO A O     1 
ATOM   7972  C  CB    . PRO C 2 173 ? 394.945 381.336 289.778 1.00 100.99 ? 173 PRO A CB    1 
ATOM   7973  C  CG    . PRO C 2 173 ? 395.952 381.436 288.720 1.00 102.79 ? 173 PRO A CG    1 
ATOM   7974  C  CD    . PRO C 2 173 ? 395.607 380.352 287.762 1.00 99.31  ? 173 PRO A CD    1 
ATOM   7975  N  N     . ALA C 2 174 ? 391.566 382.096 289.351 1.00 104.43 ? 174 ALA A N     1 
ATOM   7976  C  CA    . ALA C 2 174 ? 390.557 383.097 289.058 1.00 108.91 ? 174 ALA A CA    1 
ATOM   7977  C  C     . ALA C 2 174 ? 390.991 384.466 289.592 1.00 109.68 ? 174 ALA A C     1 
ATOM   7978  O  O     . ALA C 2 174 ? 391.813 384.544 290.509 1.00 108.20 ? 174 ALA A O     1 
ATOM   7979  C  CB    . ALA C 2 174 ? 389.233 382.682 289.687 1.00 107.19 ? 174 ALA A CB    1 
ATOM   7980  N  N     . PRO C 2 175 ? 390.461 385.579 289.025 1.00 107.53 ? 175 PRO A N     1 
ATOM   7981  C  CA    . PRO C 2 175 ? 390.885 386.901 289.512 1.00 109.12 ? 175 PRO A CA    1 
ATOM   7982  C  C     . PRO C 2 175 ? 390.477 387.186 290.946 1.00 112.91 ? 175 PRO A C     1 
ATOM   7983  O  O     . PRO C 2 175 ? 391.329 387.500 291.784 1.00 117.54 ? 175 PRO A O     1 
ATOM   7984  C  CB    . PRO C 2 175 ? 390.200 387.873 288.543 1.00 108.28 ? 175 PRO A CB    1 
ATOM   7985  C  CG    . PRO C 2 175 ? 389.061 387.135 287.992 1.00 107.11 ? 175 PRO A CG    1 
ATOM   7986  C  CD    . PRO C 2 175 ? 389.475 385.702 287.934 1.00 109.32 ? 175 PRO A CD    1 
ATOM   7987  N  N     . GLN C 2 176 ? 389.183 387.067 291.239 1.00 118.61 ? 176 GLN A N     1 
ATOM   7988  C  CA    . GLN C 2 176 ? 388.644 387.434 292.545 1.00 116.75 ? 176 GLN A CA    1 
ATOM   7989  C  C     . GLN C 2 176 ? 388.540 386.218 293.462 1.00 117.84 ? 176 GLN A C     1 
ATOM   7990  O  O     . GLN C 2 176 ? 389.111 386.207 294.557 1.00 114.38 ? 176 GLN A O     1 
ATOM   7991  C  CB    . GLN C 2 176 ? 387.274 388.100 292.373 1.00 117.79 ? 176 GLN A CB    1 
ATOM   7992  C  CG    . GLN C 2 176 ? 387.289 389.411 291.592 1.00 120.23 ? 176 GLN A CG    1 
ATOM   7993  C  CD    . GLN C 2 176 ? 387.944 390.550 292.353 1.00 122.24 ? 176 GLN A CD    1 
ATOM   7994  O  OE1   . GLN C 2 176 ? 388.209 390.447 293.550 1.00 120.97 ? 176 GLN A OE1   1 
ATOM   7995  N  NE2   . GLN C 2 176 ? 388.203 391.650 291.656 1.00 124.51 ? 176 GLN A NE2   1 
ATOM   7996  N  N     . VAL C 2 177 ? 387.815 385.186 293.027 1.00 115.02 ? 177 VAL A N     1 
ATOM   7997  C  CA    . VAL C 2 177 ? 387.650 383.994 293.852 1.00 115.71 ? 177 VAL A CA    1 
ATOM   7998  C  C     . VAL C 2 177 ? 388.966 383.232 293.924 1.00 119.81 ? 177 VAL A C     1 
ATOM   7999  O  O     . VAL C 2 177 ? 389.830 383.339 293.043 1.00 122.98 ? 177 VAL A O     1 
ATOM   8000  C  CB    . VAL C 2 177 ? 386.512 383.084 293.342 1.00 111.75 ? 177 VAL A CB    1 
ATOM   8001  C  CG1   . VAL C 2 177 ? 385.175 383.823 293.357 1.00 112.93 ? 177 VAL A CG1   1 
ATOM   8002  C  CG2   . VAL C 2 177 ? 386.805 382.515 291.956 1.00 109.89 ? 177 VAL A CG2   1 
ATOM   8003  N  N     . SER C 2 178 ? 389.126 382.465 294.996 1.00 134.13 ? 178 SER A N     1 
ATOM   8004  C  CA    . SER C 2 178 ? 390.291 381.612 295.165 1.00 136.80 ? 178 SER A CA    1 
ATOM   8005  C  C     . SER C 2 178 ? 389.944 380.527 296.169 1.00 136.32 ? 178 SER A C     1 
ATOM   8006  O  O     . SER C 2 178 ? 388.961 380.631 296.907 1.00 137.40 ? 178 SER A O     1 
ATOM   8007  C  CB    . SER C 2 178 ? 391.511 382.409 295.631 1.00 139.43 ? 178 SER A CB    1 
ATOM   8008  O  OG    . SER C 2 178 ? 392.665 381.591 295.681 1.00 142.58 ? 178 SER A OG    1 
ATOM   8009  N  N     . THR C 2 179 ? 390.771 379.480 296.176 1.00 130.07 ? 179 THR A N     1 
ATOM   8010  C  CA    . THR C 2 179 ? 390.639 378.363 297.099 1.00 128.92 ? 179 THR A CA    1 
ATOM   8011  C  C     . THR C 2 179 ? 391.929 378.058 297.848 1.00 128.41 ? 179 THR A C     1 
ATOM   8012  O  O     . THR C 2 179 ? 391.994 377.032 298.534 1.00 126.72 ? 179 THR A O     1 
ATOM   8013  C  CB    . THR C 2 179 ? 390.188 377.100 296.345 1.00 131.59 ? 179 THR A CB    1 
ATOM   8014  O  OG1   . THR C 2 179 ? 391.135 376.791 295.316 1.00 133.72 ? 179 THR A OG1   1 
ATOM   8015  C  CG2   . THR C 2 179 ? 388.817 377.304 295.721 1.00 131.31 ? 179 THR A CG2   1 
ATOM   8016  N  N     . ALA C 2 180 ? 392.950 378.907 297.740 1.00 106.72 ? 180 ALA A N     1 
ATOM   8017  C  CA    . ALA C 2 180 ? 394.263 378.606 298.286 1.00 105.99 ? 180 ALA A CA    1 
ATOM   8018  C  C     . ALA C 2 180 ? 395.034 379.900 298.480 1.00 103.71 ? 180 ALA A C     1 
ATOM   8019  O  O     . ALA C 2 180 ? 394.861 380.852 297.714 1.00 105.07 ? 180 ALA A O     1 
ATOM   8020  C  CB    . ALA C 2 180 ? 395.034 377.668 297.361 1.00 100.82 ? 180 ALA A CB    1 
ATOM   8021  N  N     . VAL C 2 181 ? 395.882 379.923 299.509 1.00 93.12  ? 181 VAL A N     1 
ATOM   8022  C  CA    . VAL C 2 181 ? 396.685 381.109 299.792 1.00 95.10  ? 181 VAL A CA    1 
ATOM   8023  C  C     . VAL C 2 181 ? 397.981 381.083 298.984 1.00 98.38  ? 181 VAL A C     1 
ATOM   8024  O  O     . VAL C 2 181 ? 398.466 382.129 298.537 1.00 99.41  ? 181 VAL A O     1 
ATOM   8025  C  CB    . VAL C 2 181 ? 396.950 381.214 301.306 1.00 90.92  ? 181 VAL A CB    1 
ATOM   8026  C  CG1   . VAL C 2 181 ? 397.613 382.549 301.649 1.00 93.44  ? 181 VAL A CG1   1 
ATOM   8027  C  CG2   . VAL C 2 181 ? 395.649 381.031 302.085 1.00 96.70  ? 181 VAL A CG2   1 
ATOM   8028  N  N     . VAL C 2 182 ? 398.554 379.894 298.777 1.00 96.95  ? 182 VAL A N     1 
ATOM   8029  C  CA    . VAL C 2 182 ? 399.822 379.727 298.060 1.00 95.23  ? 182 VAL A CA    1 
ATOM   8030  C  C     . VAL C 2 182 ? 399.605 379.490 296.562 1.00 98.64  ? 182 VAL A C     1 
ATOM   8031  O  O     . VAL C 2 182 ? 400.529 379.069 295.846 1.00 110.80 ? 182 VAL A O     1 
ATOM   8032  C  CB    . VAL C 2 182 ? 400.651 378.583 298.683 1.00 99.46  ? 182 VAL A CB    1 
ATOM   8033  C  CG1   . VAL C 2 182 ? 401.016 378.921 300.120 1.00 99.61  ? 182 VAL A CG1   1 
ATOM   8034  C  CG2   . VAL C 2 182 ? 399.933 377.211 298.619 1.00 105.07 ? 182 VAL A CG2   1 
ATOM   8035  N  N     . GLU C 2 183 ? 398.390 379.764 296.082 1.00 99.37  ? 183 GLU A N     1 
ATOM   8036  C  CA    . GLU C 2 183 ? 398.065 379.518 294.679 1.00 102.27 ? 183 GLU A CA    1 
ATOM   8037  C  C     . GLU C 2 183 ? 398.899 380.360 293.720 1.00 105.58 ? 183 GLU A C     1 
ATOM   8038  O  O     . GLU C 2 183 ? 399.314 379.817 292.680 1.00 110.24 ? 183 GLU A O     1 
ATOM   8039  C  CB    . GLU C 2 183 ? 396.547 379.710 294.474 1.00 104.64 ? 183 GLU A CB    1 
ATOM   8040  C  CG    . GLU C 2 183 ? 396.042 380.274 293.152 1.00 110.88 ? 183 GLU A CG    1 
ATOM   8041  C  CD    . GLU C 2 183 ? 394.528 380.397 293.154 1.00 114.19 ? 183 GLU A CD    1 
ATOM   8042  O  OE1   . GLU C 2 183 ? 394.006 381.396 292.619 1.00 116.83 ? 183 GLU A OE1   1 
ATOM   8043  O  OE2   . GLU C 2 183 ? 393.855 379.493 293.696 1.00 107.62 ? 183 GLU A OE2   1 
ATOM   8044  N  N     . PRO C 2 184 ? 399.140 381.656 293.958 1.00 98.72  ? 184 PRO A N     1 
ATOM   8045  C  CA    . PRO C 2 184 ? 400.070 382.388 293.078 1.00 101.39 ? 184 PRO A CA    1 
ATOM   8046  C  C     . PRO C 2 184 ? 401.472 381.802 293.026 1.00 99.32  ? 184 PRO A C     1 
ATOM   8047  O  O     . PRO C 2 184 ? 402.068 381.762 291.943 1.00 106.56 ? 184 PRO A O     1 
ATOM   8048  C  CB    . PRO C 2 184 ? 400.061 383.797 293.676 1.00 96.67  ? 184 PRO A CB    1 
ATOM   8049  C  CG    . PRO C 2 184 ? 398.699 383.935 294.228 1.00 99.55  ? 184 PRO A CG    1 
ATOM   8050  C  CD    . PRO C 2 184 ? 398.357 382.585 294.795 1.00 99.52  ? 184 PRO A CD    1 
ATOM   8051  N  N     . TYR C 2 185 ? 402.011 381.332 294.156 1.00 92.26  ? 185 TYR A N     1 
ATOM   8052  C  CA    . TYR C 2 185 ? 403.326 380.693 294.144 1.00 92.08  ? 185 TYR A CA    1 
ATOM   8053  C  C     . TYR C 2 185 ? 403.319 379.451 293.265 1.00 98.52  ? 185 TYR A C     1 
ATOM   8054  O  O     . TYR C 2 185 ? 404.202 379.272 292.409 1.00 104.10 ? 185 TYR A O     1 
ATOM   8055  C  CB    . TYR C 2 185 ? 403.749 380.310 295.567 1.00 92.25  ? 185 TYR A CB    1 
ATOM   8056  C  CG    . TYR C 2 185 ? 404.230 381.419 296.496 1.00 91.14  ? 185 TYR A CG    1 
ATOM   8057  C  CD1   . TYR C 2 185 ? 404.234 382.758 296.119 1.00 93.40  ? 185 TYR A CD1   1 
ATOM   8058  C  CD2   . TYR C 2 185 ? 404.703 381.104 297.761 1.00 94.85  ? 185 TYR A CD2   1 
ATOM   8059  C  CE1   . TYR C 2 185 ? 404.685 383.739 296.978 1.00 98.73  ? 185 TYR A CE1   1 
ATOM   8060  C  CE2   . TYR C 2 185 ? 405.154 382.078 298.622 1.00 94.46  ? 185 TYR A CE2   1 
ATOM   8061  C  CZ    . TYR C 2 185 ? 405.143 383.392 298.228 1.00 98.89  ? 185 TYR A CZ    1 
ATOM   8062  O  OH    . TYR C 2 185 ? 405.596 384.361 299.090 1.00 106.00 ? 185 TYR A OH    1 
ATOM   8063  N  N     . ASN C 2 186 ? 402.319 378.582 293.463 1.00 109.83 ? 186 ASN A N     1 
ATOM   8064  C  CA    . ASN C 2 186 ? 402.237 377.356 292.674 1.00 110.43 ? 186 ASN A CA    1 
ATOM   8065  C  C     . ASN C 2 186 ? 402.086 377.663 291.191 1.00 114.97 ? 186 ASN A C     1 
ATOM   8066  O  O     . ASN C 2 186 ? 402.760 377.055 290.348 1.00 121.05 ? 186 ASN A O     1 
ATOM   8067  C  CB    . ASN C 2 186 ? 401.068 376.497 293.156 1.00 106.26 ? 186 ASN A CB    1 
ATOM   8068  C  CG    . ASN C 2 186 ? 401.210 376.080 294.602 1.00 108.21 ? 186 ASN A CG    1 
ATOM   8069  O  OD1   . ASN C 2 186 ? 402.312 376.047 295.144 1.00 111.57 ? 186 ASN A OD1   1 
ATOM   8070  N  ND2   . ASN C 2 186 ? 400.091 375.751 295.234 1.00 114.13 ? 186 ASN A ND2   1 
ATOM   8071  N  N     . SER C 2 187 ? 401.229 378.629 290.856 1.00 104.18 ? 187 SER A N     1 
ATOM   8072  C  CA    . SER C 2 187 ? 400.980 378.945 289.457 1.00 101.85 ? 187 SER A CA    1 
ATOM   8073  C  C     . SER C 2 187 ? 402.206 379.553 288.792 1.00 106.18 ? 187 SER A C     1 
ATOM   8074  O  O     . SER C 2 187 ? 402.521 379.213 287.649 1.00 111.77 ? 187 SER A O     1 
ATOM   8075  C  CB    . SER C 2 187 ? 399.787 379.888 289.343 1.00 101.76 ? 187 SER A CB    1 
ATOM   8076  O  OG    . SER C 2 187 ? 400.007 381.053 290.109 1.00 116.23 ? 187 SER A OG    1 
ATOM   8077  N  N     . ILE C 2 188 ? 402.917 380.447 289.484 1.00 104.63 ? 188 ILE A N     1 
ATOM   8078  C  CA    . ILE C 2 188 ? 404.099 381.063 288.886 1.00 100.67 ? 188 ILE A CA    1 
ATOM   8079  C  C     . ILE C 2 188 ? 405.180 380.014 288.652 1.00 98.98  ? 188 ILE A C     1 
ATOM   8080  O  O     . ILE C 2 188 ? 405.785 379.960 287.573 1.00 108.26 ? 188 ILE A O     1 
ATOM   8081  C  CB    . ILE C 2 188 ? 404.607 382.222 289.766 1.00 103.34 ? 188 ILE A CB    1 
ATOM   8082  C  CG1   . ILE C 2 188 ? 403.623 383.408 289.756 1.00 106.15 ? 188 ILE A CG1   1 
ATOM   8083  C  CG2   . ILE C 2 188 ? 406.000 382.685 289.326 1.00 101.20 ? 188 ILE A CG2   1 
ATOM   8084  C  CD1   . ILE C 2 188 ? 403.549 384.225 288.466 1.00 104.67 ? 188 ILE A CD1   1 
ATOM   8085  N  N     . LEU C 2 189 ? 405.421 379.151 289.646 1.00 91.68  ? 189 LEU A N     1 
ATOM   8086  C  CA    . LEU C 2 189 ? 406.465 378.141 289.491 1.00 91.92  ? 189 LEU A CA    1 
ATOM   8087  C  C     . LEU C 2 189 ? 406.126 377.151 288.380 1.00 100.71 ? 189 LEU A C     1 
ATOM   8088  O  O     . LEU C 2 189 ? 406.983 376.820 287.543 1.00 106.80 ? 189 LEU A O     1 
ATOM   8089  C  CB    . LEU C 2 189 ? 406.681 377.411 290.816 1.00 95.01  ? 189 LEU A CB    1 
ATOM   8090  C  CG    . LEU C 2 189 ? 407.229 378.272 291.960 1.00 98.50  ? 189 LEU A CG    1 
ATOM   8091  C  CD1   . LEU C 2 189 ? 406.994 377.618 293.311 1.00 98.76  ? 189 LEU A CD1   1 
ATOM   8092  C  CD2   . LEU C 2 189 ? 408.713 378.545 291.762 1.00 102.38 ? 189 LEU A CD2   1 
ATOM   8093  N  N     . THR C 2 190 ? 404.873 376.689 288.328 1.00 110.11 ? 190 THR A N     1 
ATOM   8094  C  CA    . THR C 2 190 ? 404.534 375.701 287.315 1.00 111.19 ? 190 THR A CA    1 
ATOM   8095  C  C     . THR C 2 190 ? 404.457 376.321 285.928 1.00 112.80 ? 190 THR A C     1 
ATOM   8096  O  O     . THR C 2 190 ? 404.781 375.649 284.948 1.00 121.21 ? 190 THR A O     1 
ATOM   8097  C  CB    . THR C 2 190 ? 403.236 374.983 287.677 1.00 109.97 ? 190 THR A CB    1 
ATOM   8098  O  OG1   . THR C 2 190 ? 403.116 373.786 286.898 1.00 115.76 ? 190 THR A OG1   1 
ATOM   8099  C  CG2   . THR C 2 190 ? 402.021 375.854 287.444 1.00 109.91 ? 190 THR A CG2   1 
ATOM   8100  N  N     . THR C 2 191 ? 404.057 377.592 285.810 1.00 111.77 ? 191 THR A N     1 
ATOM   8101  C  CA    . THR C 2 191 ? 404.103 378.239 284.504 1.00 108.64 ? 191 THR A CA    1 
ATOM   8102  C  C     . THR C 2 191 ? 405.541 378.413 284.041 1.00 105.70 ? 191 THR A C     1 
ATOM   8103  O  O     . THR C 2 191 ? 405.834 378.261 282.850 1.00 104.40 ? 191 THR A O     1 
ATOM   8104  C  CB    . THR C 2 191 ? 403.399 379.594 284.543 1.00 107.58 ? 191 THR A CB    1 
ATOM   8105  O  OG1   . THR C 2 191 ? 403.790 380.308 285.719 1.00 122.31 ? 191 THR A OG1   1 
ATOM   8106  C  CG2   . THR C 2 191 ? 401.890 379.410 284.540 1.00 111.52 ? 191 THR A CG2   1 
ATOM   8107  N  N     . HIS C 2 192 ? 406.450 378.720 284.973 1.00 101.62 ? 192 HIS A N     1 
ATOM   8108  C  CA    . HIS C 2 192 ? 407.862 378.819 284.622 1.00 96.07  ? 192 HIS A CA    1 
ATOM   8109  C  C     . HIS C 2 192 ? 408.393 377.498 284.087 1.00 100.26 ? 192 HIS A C     1 
ATOM   8110  O  O     . HIS C 2 192 ? 409.098 377.473 283.073 1.00 106.11 ? 192 HIS A O     1 
ATOM   8111  C  CB    . HIS C 2 192 ? 408.678 379.251 285.836 1.00 95.77  ? 192 HIS A CB    1 
ATOM   8112  C  CG    . HIS C 2 192 ? 410.156 379.130 285.640 1.00 98.27  ? 192 HIS A CG    1 
ATOM   8113  N  ND1   . HIS C 2 192 ? 410.976 378.492 286.545 1.00 101.49 ? 192 HIS A ND1   1 
ATOM   8114  C  CD2   . HIS C 2 192 ? 410.965 379.578 284.651 1.00 101.24 ? 192 HIS A CD2   1 
ATOM   8115  C  CE1   . HIS C 2 192 ? 412.224 378.542 286.118 1.00 101.00 ? 192 HIS A CE1   1 
ATOM   8116  N  NE2   . HIS C 2 192 ? 412.246 379.196 284.971 1.00 102.02 ? 192 HIS A NE2   1 
ATOM   8117  N  N     . THR C 2 193 ? 408.067 376.388 284.753 1.00 111.59 ? 193 THR A N     1 
ATOM   8118  C  CA    . THR C 2 193 ? 408.557 375.096 284.272 1.00 111.12 ? 193 THR A CA    1 
ATOM   8119  C  C     . THR C 2 193 ? 407.808 374.615 283.029 1.00 110.38 ? 193 THR A C     1 
ATOM   8120  O  O     . THR C 2 193 ? 408.358 373.830 282.248 1.00 112.27 ? 193 THR A O     1 
ATOM   8121  C  CB    . THR C 2 193 ? 408.459 374.041 285.371 1.00 113.90 ? 193 THR A CB    1 
ATOM   8122  O  OG1   . THR C 2 193 ? 407.217 374.192 286.063 1.00 119.56 ? 193 THR A OG1   1 
ATOM   8123  C  CG2   . THR C 2 193 ? 409.616 374.169 286.358 1.00 111.42 ? 193 THR A CG2   1 
ATOM   8124  N  N     . THR C 2 194 ? 406.569 375.067 282.825 1.00 114.13 ? 194 THR A N     1 
ATOM   8125  C  CA    . THR C 2 194 ? 405.719 374.579 281.749 1.00 112.07 ? 194 THR A CA    1 
ATOM   8126  C  C     . THR C 2 194 ? 405.870 375.369 280.453 1.00 116.86 ? 194 THR A C     1 
ATOM   8127  O  O     . THR C 2 194 ? 405.529 374.845 279.386 1.00 122.92 ? 194 THR A O     1 
ATOM   8128  C  CB    . THR C 2 194 ? 404.256 374.618 282.218 1.00 113.22 ? 194 THR A CB    1 
ATOM   8129  O  OG1   . THR C 2 194 ? 404.127 373.866 283.431 1.00 117.53 ? 194 THR A OG1   1 
ATOM   8130  C  CG2   . THR C 2 194 ? 403.311 374.034 281.185 1.00 109.66 ? 194 THR A CG2   1 
ATOM   8131  N  N     . LEU C 2 195 ? 406.380 376.605 280.517 1.00 117.86 ? 195 LEU A N     1 
ATOM   8132  C  CA    . LEU C 2 195 ? 406.477 377.437 279.320 1.00 114.15 ? 195 LEU A CA    1 
ATOM   8133  C  C     . LEU C 2 195 ? 407.398 376.834 278.265 1.00 114.65 ? 195 LEU A C     1 
ATOM   8134  O  O     . LEU C 2 195 ? 407.180 377.045 277.066 1.00 115.21 ? 195 LEU A O     1 
ATOM   8135  C  CB    . LEU C 2 195 ? 406.967 378.834 279.699 1.00 110.88 ? 195 LEU A CB    1 
ATOM   8136  C  CG    . LEU C 2 195 ? 406.602 379.967 278.740 1.00 112.86 ? 195 LEU A CG    1 
ATOM   8137  C  CD1   . LEU C 2 195 ? 405.142 380.366 278.885 1.00 113.03 ? 195 LEU A CD1   1 
ATOM   8138  C  CD2   . LEU C 2 195 ? 407.507 381.163 278.971 1.00 113.03 ? 195 LEU A CD2   1 
ATOM   8139  N  N     . GLU C 2 196 ? 408.417 376.077 278.681 1.00 116.93 ? 196 GLU A N     1 
ATOM   8140  C  CA    . GLU C 2 196 ? 409.361 375.520 277.715 1.00 116.04 ? 196 GLU A CA    1 
ATOM   8141  C  C     . GLU C 2 196 ? 408.810 374.251 277.078 1.00 116.67 ? 196 GLU A C     1 
ATOM   8142  O  O     . GLU C 2 196 ? 408.993 374.024 275.877 1.00 114.93 ? 196 GLU A O     1 
ATOM   8143  C  CB    . GLU C 2 196 ? 410.716 375.223 278.368 1.00 115.72 ? 196 GLU A CB    1 
ATOM   8144  C  CG    . GLU C 2 196 ? 411.271 376.284 279.318 1.00 118.15 ? 196 GLU A CG    1 
ATOM   8145  C  CD    . GLU C 2 196 ? 410.802 376.107 280.747 1.00 123.09 ? 196 GLU A CD    1 
ATOM   8146  O  OE1   . GLU C 2 196 ? 411.643 376.162 281.668 1.00 124.15 ? 196 GLU A OE1   1 
ATOM   8147  O  OE2   . GLU C 2 196 ? 409.588 375.897 280.942 1.00 123.93 ? 196 GLU A OE2   1 
ATOM   8148  N  N     . HIS C 2 197 ? 408.129 373.420 277.866 1.00 119.37 ? 197 HIS A N     1 
ATOM   8149  C  CA    . HIS C 2 197 ? 407.743 372.084 277.432 1.00 120.33 ? 197 HIS A CA    1 
ATOM   8150  C  C     . HIS C 2 197 ? 406.357 372.032 276.810 1.00 118.16 ? 197 HIS A C     1 
ATOM   8151  O  O     . HIS C 2 197 ? 406.109 371.185 275.945 1.00 116.41 ? 197 HIS A O     1 
ATOM   8152  C  CB    . HIS C 2 197 ? 407.804 371.125 278.621 1.00 117.59 ? 197 HIS A CB    1 
ATOM   8153  C  CG    . HIS C 2 197 ? 409.134 371.110 279.306 1.00 121.30 ? 197 HIS A CG    1 
ATOM   8154  N  ND1   . HIS C 2 197 ? 410.301 370.771 278.657 1.00 117.90 ? 197 HIS A ND1   1 
ATOM   8155  C  CD2   . HIS C 2 197 ? 409.484 371.402 280.581 1.00 122.68 ? 197 HIS A CD2   1 
ATOM   8156  C  CE1   . HIS C 2 197 ? 411.312 370.851 279.503 1.00 117.83 ? 197 HIS A CE1   1 
ATOM   8157  N  NE2   . HIS C 2 197 ? 410.843 371.231 280.677 1.00 123.19 ? 197 HIS A NE2   1 
ATOM   8158  N  N     . SER C 2 198 ? 405.449 372.908 277.224 1.00 122.47 ? 198 SER A N     1 
ATOM   8159  C  CA    . SER C 2 198 ? 404.105 372.903 276.671 1.00 117.68 ? 198 SER A CA    1 
ATOM   8160  C  C     . SER C 2 198 ? 404.115 373.364 275.221 1.00 121.58 ? 198 SER A C     1 
ATOM   8161  O  O     . SER C 2 198 ? 404.886 374.245 274.832 1.00 126.17 ? 198 SER A O     1 
ATOM   8162  C  CB    . SER C 2 198 ? 403.195 373.817 277.483 1.00 120.46 ? 198 SER A CB    1 
ATOM   8163  O  OG    . SER C 2 198 ? 401.843 373.673 277.089 1.00 123.60 ? 198 SER A OG    1 
ATOM   8164  N  N     . ASP C 2 199 ? 403.244 372.753 274.420 1.00 111.86 ? 199 ASP A N     1 
ATOM   8165  C  CA    . ASP C 2 199 ? 402.947 373.231 273.075 1.00 113.75 ? 199 ASP A CA    1 
ATOM   8166  C  C     . ASP C 2 199 ? 401.787 374.213 273.059 1.00 111.94 ? 199 ASP A C     1 
ATOM   8167  O  O     . ASP C 2 199 ? 401.858 375.231 272.370 1.00 115.56 ? 199 ASP A O     1 
ATOM   8168  C  CB    . ASP C 2 199 ? 402.626 372.057 272.142 1.00 114.56 ? 199 ASP A CB    1 
ATOM   8169  C  CG    . ASP C 2 199 ? 403.865 371.466 271.490 1.00 120.02 ? 199 ASP A CG    1 
ATOM   8170  O  OD1   . ASP C 2 199 ? 404.984 371.674 272.004 1.00 122.56 ? 199 ASP A OD1   1 
ATOM   8171  O  OD2   . ASP C 2 199 ? 403.717 370.792 270.450 1.00 118.22 ? 199 ASP A OD2   1 
ATOM   8172  N  N     . CYS C 2 200 ? 400.724 373.938 273.812 1.00 106.81 ? 200 CYS A N     1 
ATOM   8173  C  CA    . CYS C 2 200 ? 399.581 374.846 273.872 1.00 105.56 ? 200 CYS A CA    1 
ATOM   8174  C  C     . CYS C 2 200 ? 398.714 374.454 275.056 1.00 104.98 ? 200 CYS A C     1 
ATOM   8175  O  O     . CYS C 2 200 ? 398.326 373.288 275.172 1.00 116.72 ? 200 CYS A O     1 
ATOM   8176  C  CB    . CYS C 2 200 ? 398.786 374.798 272.570 1.00 108.77 ? 200 CYS A CB    1 
ATOM   8177  S  SG    . CYS C 2 200 ? 397.252 375.738 272.594 1.00 120.01 ? 200 CYS A SG    1 
ATOM   8178  N  N     . ALA C 2 201 ? 398.412 375.423 275.921 1.00 83.10  ? 201 ALA A N     1 
ATOM   8179  C  CA    . ALA C 2 201 ? 397.640 375.214 277.141 1.00 88.62  ? 201 ALA A CA    1 
ATOM   8180  C  C     . ALA C 2 201 ? 396.350 376.019 277.061 1.00 98.55  ? 201 ALA A C     1 
ATOM   8181  O  O     . ALA C 2 201 ? 396.389 377.253 277.024 1.00 101.76 ? 201 ALA A O     1 
ATOM   8182  C  CB    . ALA C 2 201 ? 398.447 375.621 278.372 1.00 90.37  ? 201 ALA A CB    1 
ATOM   8183  N  N     . PHE C 2 202 ? 395.217 375.323 277.052 1.00 101.79 ? 202 PHE A N     1 
ATOM   8184  C  CA    . PHE C 2 202 ? 393.916 375.974 276.974 1.00 95.35  ? 202 PHE A CA    1 
ATOM   8185  C  C     . PHE C 2 202 ? 393.453 376.362 278.369 1.00 96.30  ? 202 PHE A C     1 
ATOM   8186  O  O     . PHE C 2 202 ? 393.627 375.600 279.324 1.00 102.20 ? 202 PHE A O     1 
ATOM   8187  C  CB    . PHE C 2 202 ? 392.897 375.045 276.325 1.00 96.62  ? 202 PHE A CB    1 
ATOM   8188  C  CG    . PHE C 2 202 ? 393.382 374.424 275.054 1.00 102.25 ? 202 PHE A CG    1 
ATOM   8189  C  CD1   . PHE C 2 202 ? 393.445 375.155 273.885 1.00 101.16 ? 202 PHE A CD1   1 
ATOM   8190  C  CD2   . PHE C 2 202 ? 393.785 373.104 275.034 1.00 101.09 ? 202 PHE A CD2   1 
ATOM   8191  C  CE1   . PHE C 2 202 ? 393.902 374.575 272.719 1.00 100.34 ? 202 PHE A CE1   1 
ATOM   8192  C  CE2   . PHE C 2 202 ? 394.231 372.520 273.874 1.00 98.43  ? 202 PHE A CE2   1 
ATOM   8193  C  CZ    . PHE C 2 202 ? 394.291 373.257 272.714 1.00 97.48  ? 202 PHE A CZ    1 
ATOM   8194  N  N     . MET C 2 203 ? 392.855 377.546 278.481 1.00 108.94 ? 203 MET A N     1 
ATOM   8195  C  CA    . MET C 2 203 ? 392.638 378.183 279.770 1.00 103.63 ? 203 MET A CA    1 
ATOM   8196  C  C     . MET C 2 203 ? 391.180 378.022 280.185 1.00 104.55 ? 203 MET A C     1 
ATOM   8197  O  O     . MET C 2 203 ? 390.276 378.076 279.346 1.00 114.96 ? 203 MET A O     1 
ATOM   8198  C  CB    . MET C 2 203 ? 392.998 379.667 279.701 1.00 113.24 ? 203 MET A CB    1 
ATOM   8199  C  CG    . MET C 2 203 ? 394.494 380.004 279.510 1.00 113.02 ? 203 MET A CG    1 
ATOM   8200  S  SD    . MET C 2 203 ? 395.854 378.831 279.810 1.00 119.23 ? 203 MET A SD    1 
ATOM   8201  C  CE    . MET C 2 203 ? 395.654 378.247 281.482 1.00 114.18 ? 203 MET A CE    1 
ATOM   8202  N  N     . VAL C 2 204 ? 390.962 377.828 281.485 1.00 91.92  ? 204 VAL A N     1 
ATOM   8203  C  CA    . VAL C 2 204 ? 389.633 377.649 282.062 1.00 97.50  ? 204 VAL A CA    1 
ATOM   8204  C  C     . VAL C 2 204 ? 389.612 378.395 283.391 1.00 103.43 ? 204 VAL A C     1 
ATOM   8205  O  O     . VAL C 2 204 ? 390.625 378.440 284.098 1.00 111.05 ? 204 VAL A O     1 
ATOM   8206  C  CB    . VAL C 2 204 ? 389.296 376.144 282.222 1.00 103.58 ? 204 VAL A CB    1 
ATOM   8207  C  CG1   . VAL C 2 204 ? 388.296 375.868 283.361 1.00 104.75 ? 204 VAL A CG1   1 
ATOM   8208  C  CG2   . VAL C 2 204 ? 388.765 375.583 280.910 1.00 102.48 ? 204 VAL A CG2   1 
ATOM   8209  N  N     . ASP C 2 205 ? 388.464 378.995 283.719 1.00 104.40 ? 205 ASP A N     1 
ATOM   8210  C  CA    . ASP C 2 205 ? 388.306 379.796 284.927 1.00 99.99  ? 205 ASP A CA    1 
ATOM   8211  C  C     . ASP C 2 205 ? 386.979 379.477 285.601 1.00 106.17 ? 205 ASP A C     1 
ATOM   8212  O  O     . ASP C 2 205 ? 385.910 379.589 284.984 1.00 115.04 ? 205 ASP A O     1 
ATOM   8213  C  CB    . ASP C 2 205 ? 388.397 381.285 284.599 1.00 106.11 ? 205 ASP A CB    1 
ATOM   8214  C  CG    . ASP C 2 205 ? 388.678 382.138 285.818 1.00 113.44 ? 205 ASP A CG    1 
ATOM   8215  O  OD1   . ASP C 2 205 ? 388.491 381.653 286.952 1.00 114.62 ? 205 ASP A OD1   1 
ATOM   8216  O  OD2   . ASP C 2 205 ? 389.091 383.303 285.640 1.00 117.59 ? 205 ASP A OD2   1 
ATOM   8217  N  N     . ASN C 2 206 ? 387.061 379.110 286.882 1.00 106.29 ? 206 ASN A N     1 
ATOM   8218  C  CA    . ASN C 2 206 ? 385.874 378.731 287.639 1.00 109.96 ? 206 ASN A CA    1 
ATOM   8219  C  C     . ASN C 2 206 ? 384.918 379.904 287.801 1.00 110.87 ? 206 ASN A C     1 
ATOM   8220  O  O     . ASN C 2 206 ? 383.701 379.729 287.707 1.00 121.46 ? 206 ASN A O     1 
ATOM   8221  C  CB    . ASN C 2 206 ? 386.282 378.182 289.010 1.00 108.44 ? 206 ASN A CB    1 
ATOM   8222  C  CG    . ASN C 2 206 ? 386.929 376.771 288.965 1.00 106.63 ? 206 ASN A CG    1 
ATOM   8223  O  OD1   . ASN C 2 206 ? 387.124 376.180 290.026 1.00 107.50 ? 206 ASN A OD1   1 
ATOM   8224  N  ND2   . ASN C 2 206 ? 387.269 376.238 287.780 1.00 110.38 ? 206 ASN A ND2   1 
ATOM   8225  N  N     . GLU C 2 207 ? 385.447 381.104 288.054 1.00 116.91 ? 207 GLU A N     1 
ATOM   8226  C  CA    . GLU C 2 207 ? 384.586 382.275 288.199 1.00 121.99 ? 207 GLU A CA    1 
ATOM   8227  C  C     . GLU C 2 207 ? 383.862 382.587 286.899 1.00 121.28 ? 207 GLU A C     1 
ATOM   8228  O  O     . GLU C 2 207 ? 382.668 382.923 286.904 1.00 122.45 ? 207 GLU A O     1 
ATOM   8229  C  CB    . GLU C 2 207 ? 385.411 383.480 288.638 1.00 122.38 ? 207 GLU A CB    1 
ATOM   8230  C  CG    . GLU C 2 207 ? 384.585 384.604 289.237 1.00 125.84 ? 207 GLU A CG    1 
ATOM   8231  C  CD    . GLU C 2 207 ? 385.428 385.790 289.653 1.00 128.10 ? 207 GLU A CD    1 
ATOM   8232  O  OE1   . GLU C 2 207 ? 386.559 385.577 290.139 1.00 128.22 ? 207 GLU A OE1   1 
ATOM   8233  O  OE2   . GLU C 2 207 ? 384.960 386.937 289.496 1.00 129.05 ? 207 GLU A OE2   1 
ATOM   8234  N  N     . ALA C 2 208 ? 384.572 382.487 285.775 1.00 112.02 ? 208 ALA A N     1 
ATOM   8235  C  CA    . ALA C 2 208 ? 383.949 382.731 284.483 1.00 110.78 ? 208 ALA A CA    1 
ATOM   8236  C  C     . ALA C 2 208 ? 382.854 381.715 284.206 1.00 112.22 ? 208 ALA A C     1 
ATOM   8237  O  O     . ALA C 2 208 ? 381.779 382.073 283.712 1.00 116.21 ? 208 ALA A O     1 
ATOM   8238  C  CB    . ALA C 2 208 ? 385.002 382.695 283.380 1.00 116.80 ? 208 ALA A CB    1 
ATOM   8239  N  N     . ILE C 2 209 ? 383.097 380.443 284.533 1.00 107.42 ? 209 ILE A N     1 
ATOM   8240  C  CA    . ILE C 2 209 ? 382.067 379.440 284.276 1.00 104.54 ? 209 ILE A CA    1 
ATOM   8241  C  C     . ILE C 2 209 ? 380.891 379.628 285.230 1.00 105.65 ? 209 ILE A C     1 
ATOM   8242  O  O     . ILE C 2 209 ? 379.744 379.355 284.860 1.00 110.26 ? 209 ILE A O     1 
ATOM   8243  C  CB    . ILE C 2 209 ? 382.621 378.002 284.354 1.00 101.10 ? 209 ILE A CB    1 
ATOM   8244  C  CG1   . ILE C 2 209 ? 383.773 377.765 283.364 1.00 102.22 ? 209 ILE A CG1   1 
ATOM   8245  C  CG2   . ILE C 2 209 ? 381.508 377.007 284.013 1.00 105.45 ? 209 ILE A CG2   1 
ATOM   8246  C  CD1   . ILE C 2 209 ? 384.708 376.650 283.778 1.00 105.59 ? 209 ILE A CD1   1 
ATOM   8247  N  N     . TYR C 2 210 ? 381.146 380.071 286.467 1.00 105.89 ? 210 TYR A N     1 
ATOM   8248  C  CA    . TYR C 2 210 ? 380.055 380.399 287.383 1.00 99.40  ? 210 TYR A CA    1 
ATOM   8249  C  C     . TYR C 2 210 ? 379.175 381.496 286.806 1.00 102.92 ? 210 TYR A C     1 
ATOM   8250  O  O     . TYR C 2 210 ? 377.941 381.398 286.825 1.00 110.43 ? 210 TYR A O     1 
ATOM   8251  C  CB    . TYR C 2 210 ? 380.605 380.859 288.740 1.00 103.36 ? 210 TYR A CB    1 
ATOM   8252  C  CG    . TYR C 2 210 ? 381.297 379.829 289.620 1.00 104.07 ? 210 TYR A CG    1 
ATOM   8253  C  CD1   . TYR C 2 210 ? 380.896 378.500 289.651 1.00 103.32 ? 210 TYR A CD1   1 
ATOM   8254  C  CD2   . TYR C 2 210 ? 382.340 380.211 290.452 1.00 103.72 ? 210 TYR A CD2   1 
ATOM   8255  C  CE1   . TYR C 2 210 ? 381.527 377.584 290.468 1.00 105.71 ? 210 TYR A CE1   1 
ATOM   8256  C  CE2   . TYR C 2 210 ? 382.976 379.301 291.269 1.00 106.46 ? 210 TYR A CE2   1 
ATOM   8257  C  CZ    . TYR C 2 210 ? 382.564 377.990 291.274 1.00 110.71 ? 210 TYR A CZ    1 
ATOM   8258  O  OH    . TYR C 2 210 ? 383.193 377.076 292.087 1.00 115.56 ? 210 TYR A OH    1 
ATOM   8259  N  N     . ASP C 2 211 ? 379.798 382.557 286.293 1.00 110.52 ? 211 ASP A N     1 
ATOM   8260  C  CA    . ASP C 2 211 ? 379.023 383.645 285.707 1.00 111.43 ? 211 ASP A CA    1 
ATOM   8261  C  C     . ASP C 2 211 ? 378.276 383.182 284.465 1.00 114.72 ? 211 ASP A C     1 
ATOM   8262  O  O     . ASP C 2 211 ? 377.136 383.599 284.232 1.00 118.91 ? 211 ASP A O     1 
ATOM   8263  C  CB    . ASP C 2 211 ? 379.928 384.833 285.380 1.00 116.42 ? 211 ASP A CB    1 
ATOM   8264  C  CG    . ASP C 2 211 ? 379.925 385.886 286.472 1.00 122.30 ? 211 ASP A CG    1 
ATOM   8265  O  OD1   . ASP C 2 211 ? 378.830 386.333 286.877 1.00 124.34 ? 211 ASP A OD1   1 
ATOM   8266  O  OD2   . ASP C 2 211 ? 381.019 386.262 286.937 1.00 122.75 ? 211 ASP A OD2   1 
ATOM   8267  N  N     . ILE C 2 212 ? 378.896 382.311 283.663 1.00 112.37 ? 212 ILE A N     1 
ATOM   8268  C  CA    . ILE C 2 212 ? 378.231 381.773 282.478 1.00 113.50 ? 212 ILE A CA    1 
ATOM   8269  C  C     . ILE C 2 212 ? 377.000 380.971 282.881 1.00 114.60 ? 212 ILE A C     1 
ATOM   8270  O  O     . ILE C 2 212 ? 375.925 381.116 282.285 1.00 119.39 ? 212 ILE A O     1 
ATOM   8271  C  CB    . ILE C 2 212 ? 379.225 380.926 281.656 1.00 110.63 ? 212 ILE A CB    1 
ATOM   8272  C  CG1   . ILE C 2 212 ? 380.211 381.833 280.918 1.00 110.77 ? 212 ILE A CG1   1 
ATOM   8273  C  CG2   . ILE C 2 212 ? 378.504 380.018 280.644 1.00 112.37 ? 212 ILE A CG2   1 
ATOM   8274  C  CD1   . ILE C 2 212 ? 381.538 381.173 280.604 1.00 113.76 ? 212 ILE A CD1   1 
ATOM   8275  N  N     . CYS C 2 213 ? 377.139 380.119 283.899 1.00 112.73 ? 213 CYS A N     1 
ATOM   8276  C  CA    . CYS C 2 213 ? 376.017 379.309 284.361 1.00 113.36 ? 213 CYS A CA    1 
ATOM   8277  C  C     . CYS C 2 213 ? 374.897 380.186 284.902 1.00 113.61 ? 213 CYS A C     1 
ATOM   8278  O  O     . CYS C 2 213 ? 373.715 379.940 284.634 1.00 117.66 ? 213 CYS A O     1 
ATOM   8279  C  CB    . CYS C 2 213 ? 376.490 378.327 285.432 1.00 114.50 ? 213 CYS A CB    1 
ATOM   8280  S  SG    . CYS C 2 213 ? 377.401 376.903 284.798 1.00 122.21 ? 213 CYS A SG    1 
ATOM   8281  N  N     . ARG C 2 214 ? 375.249 381.218 285.670 1.00 124.45 ? 214 ARG A N     1 
ATOM   8282  C  CA    . ARG C 2 214 ? 374.220 382.061 286.268 1.00 126.16 ? 214 ARG A CA    1 
ATOM   8283  C  C     . ARG C 2 214 ? 373.506 382.904 285.219 1.00 124.67 ? 214 ARG A C     1 
ATOM   8284  O  O     . ARG C 2 214 ? 372.285 383.087 285.291 1.00 128.31 ? 214 ARG A O     1 
ATOM   8285  C  CB    . ARG C 2 214 ? 374.833 382.950 287.350 1.00 130.28 ? 214 ARG A CB    1 
ATOM   8286  C  CG    . ARG C 2 214 ? 373.799 383.544 288.342 1.00 129.13 ? 214 ARG A CG    1 
ATOM   8287  C  CD    . ARG C 2 214 ? 373.328 384.992 288.044 1.00 129.00 ? 214 ARG A CD    1 
ATOM   8288  N  NE    . ARG C 2 214 ? 374.358 385.936 287.609 1.00 135.19 ? 214 ARG A NE    1 
ATOM   8289  C  CZ    . ARG C 2 214 ? 375.488 386.212 288.252 1.00 135.79 ? 214 ARG A CZ    1 
ATOM   8290  N  NH1   . ARG C 2 214 ? 375.733 385.760 289.473 1.00 137.86 ? 214 ARG A NH1   1 
ATOM   8291  N  NH2   . ARG C 2 214 ? 376.393 386.988 287.661 1.00 130.90 ? 214 ARG A NH2   1 
ATOM   8292  N  N     . ARG C 2 215 ? 374.241 383.421 284.232 1.00 117.38 ? 215 ARG A N     1 
ATOM   8293  C  CA    . ARG C 2 215 ? 373.625 384.286 283.229 1.00 119.11 ? 215 ARG A CA    1 
ATOM   8294  C  C     . ARG C 2 215 ? 372.840 383.473 282.207 1.00 119.39 ? 215 ARG A C     1 
ATOM   8295  O  O     . ARG C 2 215 ? 371.628 383.653 282.052 1.00 119.44 ? 215 ARG A O     1 
ATOM   8296  C  CB    . ARG C 2 215 ? 374.687 385.130 282.513 1.00 121.57 ? 215 ARG A CB    1 
ATOM   8297  C  CG    . ARG C 2 215 ? 374.761 386.582 282.962 1.00 126.20 ? 215 ARG A CG    1 
ATOM   8298  C  CD    . ARG C 2 215 ? 375.518 387.432 281.953 1.00 123.61 ? 215 ARG A CD    1 
ATOM   8299  N  NE    . ARG C 2 215 ? 376.903 387.001 281.793 1.00 122.47 ? 215 ARG A NE    1 
ATOM   8300  C  CZ    . ARG C 2 215 ? 377.875 387.195 282.677 1.00 127.69 ? 215 ARG A CZ    1 
ATOM   8301  N  NH1   . ARG C 2 215 ? 377.662 387.808 283.833 1.00 127.65 ? 215 ARG A NH1   1 
ATOM   8302  N  NH2   . ARG C 2 215 ? 379.100 386.763 282.393 1.00 128.07 ? 215 ARG A NH2   1 
ATOM   8303  N  N     . ASN C 2 216 ? 373.521 382.573 281.498 1.00 109.10 ? 216 ASN A N     1 
ATOM   8304  C  CA    . ASN C 2 216 ? 372.909 381.905 280.356 1.00 107.85 ? 216 ASN A CA    1 
ATOM   8305  C  C     . ASN C 2 216 ? 372.040 380.732 280.791 1.00 112.06 ? 216 ASN A C     1 
ATOM   8306  O  O     . ASN C 2 216 ? 370.845 380.680 280.480 1.00 118.38 ? 216 ASN A O     1 
ATOM   8307  C  CB    . ASN C 2 216 ? 374.000 381.444 279.391 1.00 110.08 ? 216 ASN A CB    1 
ATOM   8308  C  CG    . ASN C 2 216 ? 374.836 382.595 278.875 1.00 115.39 ? 216 ASN A CG    1 
ATOM   8309  O  OD1   . ASN C 2 216 ? 374.326 383.690 278.643 1.00 118.24 ? 216 ASN A OD1   1 
ATOM   8310  N  ND2   . ASN C 2 216 ? 376.128 382.358 278.704 1.00 114.18 ? 216 ASN A ND2   1 
ATOM   8311  N  N     . LEU C 2 217 ? 372.622 379.780 281.517 1.00 107.43 ? 217 LEU A N     1 
ATOM   8312  C  CA    . LEU C 2 217 ? 371.893 378.583 281.912 1.00 107.99 ? 217 LEU A CA    1 
ATOM   8313  C  C     . LEU C 2 217 ? 370.879 378.827 283.024 1.00 112.66 ? 217 LEU A C     1 
ATOM   8314  O  O     . LEU C 2 217 ? 370.089 377.922 283.313 1.00 111.37 ? 217 LEU A O     1 
ATOM   8315  C  CB    . LEU C 2 217 ? 372.873 377.493 282.353 1.00 105.64 ? 217 LEU A CB    1 
ATOM   8316  C  CG    . LEU C 2 217 ? 374.052 377.193 281.424 1.00 113.29 ? 217 LEU A CG    1 
ATOM   8317  C  CD1   . LEU C 2 217 ? 374.907 376.087 282.014 1.00 113.06 ? 217 LEU A CD1   1 
ATOM   8318  C  CD2   . LEU C 2 217 ? 373.584 376.816 280.026 1.00 113.29 ? 217 LEU A CD2   1 
ATOM   8319  N  N     . ASP C 2 218 ? 370.882 380.006 283.654 1.00 125.83 ? 218 ASP A N     1 
ATOM   8320  C  CA    . ASP C 2 218 ? 369.926 380.355 284.708 1.00 122.91 ? 218 ASP A CA    1 
ATOM   8321  C  C     . ASP C 2 218 ? 370.006 379.394 285.892 1.00 124.05 ? 218 ASP A C     1 
ATOM   8322  O  O     . ASP C 2 218 ? 369.004 379.137 286.562 1.00 122.67 ? 218 ASP A O     1 
ATOM   8323  C  CB    . ASP C 2 218 ? 368.495 380.406 284.164 1.00 123.63 ? 218 ASP A CB    1 
ATOM   8324  C  CG    . ASP C 2 218 ? 368.347 381.374 283.008 1.00 128.64 ? 218 ASP A CG    1 
ATOM   8325  O  OD1   . ASP C 2 218 ? 368.573 382.585 283.213 1.00 128.54 ? 218 ASP A OD1   1 
ATOM   8326  O  OD2   . ASP C 2 218 ? 368.006 380.924 281.894 1.00 128.54 ? 218 ASP A OD2   1 
ATOM   8327  N  N     . ILE C 2 219 ? 371.199 378.869 286.157 1.00 122.17 ? 219 ILE A N     1 
ATOM   8328  C  CA    . ILE C 2 219 ? 371.431 377.888 287.211 1.00 116.27 ? 219 ILE A CA    1 
ATOM   8329  C  C     . ILE C 2 219 ? 371.935 378.663 288.422 1.00 117.81 ? 219 ILE A C     1 
ATOM   8330  O  O     . ILE C 2 219 ? 373.074 379.136 288.440 1.00 115.59 ? 219 ILE A O     1 
ATOM   8331  C  CB    . ILE C 2 219 ? 372.428 376.810 286.774 1.00 116.45 ? 219 ILE A CB    1 
ATOM   8332  C  CG1   . ILE C 2 219 ? 371.915 376.026 285.551 1.00 119.41 ? 219 ILE A CG1   1 
ATOM   8333  C  CG2   . ILE C 2 219 ? 372.748 375.877 287.938 1.00 115.41 ? 219 ILE A CG2   1 
ATOM   8334  C  CD1   . ILE C 2 219 ? 370.617 375.233 285.750 1.00 120.21 ? 219 ILE A CD1   1 
ATOM   8335  N  N     . GLU C 2 220 ? 371.081 378.796 289.436 1.00 127.73 ? 220 GLU A N     1 
ATOM   8336  C  CA    . GLU C 2 220 ? 371.425 379.518 290.656 1.00 126.81 ? 220 GLU A CA    1 
ATOM   8337  C  C     . GLU C 2 220 ? 372.181 378.667 291.673 1.00 127.29 ? 220 GLU A C     1 
ATOM   8338  O  O     . GLU C 2 220 ? 372.612 379.211 292.696 1.00 126.85 ? 220 GLU A O     1 
ATOM   8339  C  CB    . GLU C 2 220 ? 370.154 380.089 291.313 1.00 126.44 ? 220 GLU A CB    1 
ATOM   8340  C  CG    . GLU C 2 220 ? 369.874 381.583 291.069 1.00 131.12 ? 220 GLU A CG    1 
ATOM   8341  C  CD    . GLU C 2 220 ? 370.970 382.520 291.570 1.00 133.94 ? 220 GLU A CD    1 
ATOM   8342  O  OE1   . GLU C 2 220 ? 371.944 382.038 292.187 1.00 131.43 ? 220 GLU A OE1   1 
ATOM   8343  O  OE2   . GLU C 2 220 ? 370.854 383.742 291.341 1.00 134.99 ? 220 GLU A OE2   1 
ATOM   8344  N  N     . ARG C 2 221 ? 372.359 377.365 291.423 1.00 122.79 ? 221 ARG A N     1 
ATOM   8345  C  CA    . ARG C 2 221 ? 373.136 376.480 292.296 1.00 115.39 ? 221 ARG A CA    1 
ATOM   8346  C  C     . ARG C 2 221 ? 374.086 375.646 291.443 1.00 119.05 ? 221 ARG A C     1 
ATOM   8347  O  O     . ARG C 2 221 ? 373.920 374.430 291.310 1.00 123.53 ? 221 ARG A O     1 
ATOM   8348  C  CB    . ARG C 2 221 ? 372.208 375.589 293.121 1.00 112.89 ? 221 ARG A CB    1 
ATOM   8349  N  N     . PRO C 2 222 ? 375.114 376.277 290.842 1.00 104.03 ? 222 PRO A N     1 
ATOM   8350  C  CA    . PRO C 2 222 ? 376.024 375.517 289.976 1.00 105.70 ? 222 PRO A CA    1 
ATOM   8351  C  C     . PRO C 2 222 ? 377.052 374.725 290.762 1.00 103.36 ? 222 PRO A C     1 
ATOM   8352  O  O     . PRO C 2 222 ? 377.691 375.260 291.674 1.00 102.43 ? 222 PRO A O     1 
ATOM   8353  C  CB    . PRO C 2 222 ? 376.699 376.607 289.130 1.00 107.43 ? 222 PRO A CB    1 
ATOM   8354  C  CG    . PRO C 2 222 ? 376.073 377.907 289.562 1.00 105.31 ? 222 PRO A CG    1 
ATOM   8355  C  CD    . PRO C 2 222 ? 375.585 377.664 290.941 1.00 99.21  ? 222 PRO A CD    1 
ATOM   8356  N  N     . THR C 2 223 ? 377.215 373.456 290.405 1.00 115.36 ? 223 THR A N     1 
ATOM   8357  C  CA    . THR C 2 223 ? 378.172 372.560 291.032 1.00 110.20 ? 223 THR A CA    1 
ATOM   8358  C  C     . THR C 2 223 ? 379.380 372.332 290.126 1.00 113.82 ? 223 THR A C     1 
ATOM   8359  O  O     . THR C 2 223 ? 379.378 372.626 288.920 1.00 122.69 ? 223 THR A O     1 
ATOM   8360  C  CB    . THR C 2 223 ? 377.506 371.224 291.368 1.00 113.38 ? 223 THR A CB    1 
ATOM   8361  O  OG1   . THR C 2 223 ? 376.708 370.793 290.259 1.00 122.23 ? 223 THR A OG1   1 
ATOM   8362  C  CG2   . THR C 2 223 ? 376.629 371.358 292.602 1.00 112.59 ? 223 THR A CG2   1 
ATOM   8363  N  N     . TYR C 2 224 ? 380.426 371.761 290.725 1.00 91.91  ? 224 TYR A N     1 
ATOM   8364  C  CA    . TYR C 2 224 ? 381.583 371.379 289.934 1.00 90.45  ? 224 TYR A CA    1 
ATOM   8365  C  C     . TYR C 2 224 ? 381.256 370.242 288.978 1.00 97.42  ? 224 TYR A C     1 
ATOM   8366  O  O     . TYR C 2 224 ? 381.974 370.069 287.993 1.00 103.01 ? 224 TYR A O     1 
ATOM   8367  C  CB    . TYR C 2 224 ? 382.765 370.984 290.838 1.00 83.96  ? 224 TYR A CB    1 
ATOM   8368  C  CG    . TYR C 2 224 ? 383.768 372.079 291.247 1.00 90.82  ? 224 TYR A CG    1 
ATOM   8369  C  CD1   . TYR C 2 224 ? 383.605 373.421 290.901 1.00 96.96  ? 224 TYR A CD1   1 
ATOM   8370  C  CD2   . TYR C 2 224 ? 384.906 371.742 291.958 1.00 92.82  ? 224 TYR A CD2   1 
ATOM   8371  C  CE1   . TYR C 2 224 ? 384.523 374.376 291.267 1.00 102.92 ? 224 TYR A CE1   1 
ATOM   8372  C  CE2   . TYR C 2 224 ? 385.845 372.692 292.304 1.00 96.34  ? 224 TYR A CE2   1 
ATOM   8373  C  CZ    . TYR C 2 224 ? 385.640 374.009 291.974 1.00 103.20 ? 224 TYR A CZ    1 
ATOM   8374  O  OH    . TYR C 2 224 ? 386.568 374.959 292.334 1.00 106.40 ? 224 TYR A OH    1 
ATOM   8375  N  N     . THR C 2 225 ? 380.178 369.489 289.217 1.00 108.86 ? 225 THR A N     1 
ATOM   8376  C  CA    . THR C 2 225 ? 379.654 368.616 288.173 1.00 110.28 ? 225 THR A CA    1 
ATOM   8377  C  C     . THR C 2 225 ? 379.287 369.417 286.930 1.00 111.68 ? 225 THR A C     1 
ATOM   8378  O  O     . THR C 2 225 ? 379.641 369.031 285.812 1.00 118.60 ? 225 THR A O     1 
ATOM   8379  C  CB    . THR C 2 225 ? 378.437 367.844 288.684 1.00 113.44 ? 225 THR A CB    1 
ATOM   8380  O  OG1   . THR C 2 225 ? 377.440 368.762 289.146 1.00 116.55 ? 225 THR A OG1   1 
ATOM   8381  C  CG2   . THR C 2 225 ? 378.828 366.907 289.816 1.00 111.75 ? 225 THR A CG2   1 
ATOM   8382  N  N     . ASN C 2 226 ? 378.610 370.557 287.107 1.00 110.45 ? 226 ASN A N     1 
ATOM   8383  C  CA    . ASN C 2 226 ? 378.263 371.397 285.963 1.00 112.14 ? 226 ASN A CA    1 
ATOM   8384  C  C     . ASN C 2 226 ? 379.511 371.955 285.288 1.00 114.28 ? 226 ASN A C     1 
ATOM   8385  O  O     . ASN C 2 226 ? 379.600 371.979 284.049 1.00 120.61 ? 226 ASN A O     1 
ATOM   8386  C  CB    . ASN C 2 226 ? 377.349 372.543 286.399 1.00 113.31 ? 226 ASN A CB    1 
ATOM   8387  C  CG    . ASN C 2 226 ? 376.107 372.062 287.121 1.00 117.53 ? 226 ASN A CG    1 
ATOM   8388  O  OD1   . ASN C 2 226 ? 376.160 371.709 288.297 1.00 120.86 ? 226 ASN A OD1   1 
ATOM   8389  N  ND2   . ASN C 2 226 ? 374.979 372.053 286.420 1.00 121.48 ? 226 ASN A ND2   1 
ATOM   8390  N  N     . LEU C 2 227 ? 380.483 372.411 286.085 1.00 102.19 ? 227 LEU A N     1 
ATOM   8391  C  CA    . LEU C 2 227 ? 381.702 372.968 285.497 1.00 102.17 ? 227 LEU A CA    1 
ATOM   8392  C  C     . LEU C 2 227 ? 382.469 371.913 284.707 1.00 106.00 ? 227 LEU A C     1 
ATOM   8393  O  O     . LEU C 2 227 ? 382.939 372.174 283.590 1.00 111.60 ? 227 LEU A O     1 
ATOM   8394  C  CB    . LEU C 2 227 ? 382.598 373.558 286.583 1.00 105.58 ? 227 LEU A CB    1 
ATOM   8395  C  CG    . LEU C 2 227 ? 382.263 374.967 287.073 1.00 108.39 ? 227 LEU A CG    1 
ATOM   8396  C  CD1   . LEU C 2 227 ? 381.048 374.976 287.988 1.00 108.07 ? 227 LEU A CD1   1 
ATOM   8397  C  CD2   . LEU C 2 227 ? 383.464 375.591 287.762 1.00 110.08 ? 227 LEU A CD2   1 
ATOM   8398  N  N     . ASN C 2 228 ? 382.602 370.711 285.269 1.00 100.08 ? 228 ASN A N     1 
ATOM   8399  C  CA    . ASN C 2 228 ? 383.283 369.639 284.564 1.00 99.57  ? 228 ASN A CA    1 
ATOM   8400  C  C     . ASN C 2 228 ? 382.498 369.191 283.340 1.00 102.98 ? 228 ASN A C     1 
ATOM   8401  O  O     . ASN C 2 228 ? 383.100 368.764 282.355 1.00 111.58 ? 228 ASN A O     1 
ATOM   8402  C  CB    . ASN C 2 228 ? 383.521 368.463 285.507 1.00 95.88  ? 228 ASN A CB    1 
ATOM   8403  C  CG    . ASN C 2 228 ? 384.356 368.842 286.709 1.00 103.00 ? 228 ASN A CG    1 
ATOM   8404  O  OD1   . ASN C 2 228 ? 385.000 369.890 286.727 1.00 99.82  ? 228 ASN A OD1   1 
ATOM   8405  N  ND2   . ASN C 2 228 ? 384.332 367.999 287.732 1.00 105.78 ? 228 ASN A ND2   1 
ATOM   8406  N  N     . ARG C 2 229 ? 381.165 369.284 283.375 1.00 106.64 ? 229 ARG A N     1 
ATOM   8407  C  CA    . ARG C 2 229 ? 380.381 368.994 282.176 1.00 102.94 ? 229 ARG A CA    1 
ATOM   8408  C  C     . ARG C 2 229 ? 380.704 369.981 281.063 1.00 103.72 ? 229 ARG A C     1 
ATOM   8409  O  O     . ARG C 2 229 ? 380.866 369.590 279.900 1.00 107.70 ? 229 ARG A O     1 
ATOM   8410  C  CB    . ARG C 2 229 ? 378.878 369.026 282.483 1.00 104.47 ? 229 ARG A CB    1 
ATOM   8411  C  CG    . ARG C 2 229 ? 378.191 367.661 282.534 1.00 106.72 ? 229 ARG A CG    1 
ATOM   8412  C  CD    . ARG C 2 229 ? 378.375 366.990 283.882 1.00 107.64 ? 229 ARG A CD    1 
ATOM   8413  N  NE    . ARG C 2 229 ? 377.711 365.691 283.951 1.00 114.85 ? 229 ARG A NE    1 
ATOM   8414  C  CZ    . ARG C 2 229 ? 376.445 365.481 284.300 1.00 115.88 ? 229 ARG A CZ    1 
ATOM   8415  N  NH1   . ARG C 2 229 ? 375.618 366.477 284.588 1.00 107.81 ? 229 ARG A NH1   1 
ATOM   8416  N  NH2   . ARG C 2 229 ? 375.991 364.232 284.356 1.00 118.55 ? 229 ARG A NH2   1 
ATOM   8417  N  N     . LEU C 2 230 ? 380.806 371.268 281.400 1.00 98.78  ? 230 LEU A N     1 
ATOM   8418  C  CA    . LEU C 2 230 ? 381.151 372.260 280.381 1.00 97.30  ? 230 LEU A CA    1 
ATOM   8419  C  C     . LEU C 2 230 ? 382.562 372.038 279.839 1.00 102.24 ? 230 LEU A C     1 
ATOM   8420  O  O     . LEU C 2 230 ? 382.798 372.153 278.628 1.00 113.05 ? 230 LEU A O     1 
ATOM   8421  C  CB    . LEU C 2 230 ? 381.007 373.676 280.940 1.00 99.66  ? 230 LEU A CB    1 
ATOM   8422  C  CG    . LEU C 2 230 ? 379.668 374.347 280.623 1.00 103.50 ? 230 LEU A CG    1 
ATOM   8423  C  CD1   . LEU C 2 230 ? 378.517 373.618 281.297 1.00 103.45 ? 230 LEU A CD1   1 
ATOM   8424  C  CD2   . LEU C 2 230 ? 379.680 375.803 281.043 1.00 108.68 ? 230 LEU A CD2   1 
ATOM   8425  N  N     . ILE C 2 231 ? 383.511 371.709 280.717 1.00 98.46  ? 231 ILE A N     1 
ATOM   8426  C  CA    . ILE C 2 231 ? 384.876 371.448 280.259 1.00 100.61 ? 231 ILE A CA    1 
ATOM   8427  C  C     . ILE C 2 231 ? 384.914 370.190 279.394 1.00 98.42  ? 231 ILE A C     1 
ATOM   8428  O  O     . ILE C 2 231 ? 385.678 370.105 278.418 1.00 104.39 ? 231 ILE A O     1 
ATOM   8429  C  CB    . ILE C 2 231 ? 385.836 371.347 281.461 1.00 98.59  ? 231 ILE A CB    1 
ATOM   8430  C  CG1   . ILE C 2 231 ? 385.967 372.696 282.183 1.00 98.09  ? 231 ILE A CG1   1 
ATOM   8431  C  CG2   . ILE C 2 231 ? 387.217 370.883 281.016 1.00 101.29 ? 231 ILE A CG2   1 
ATOM   8432  C  CD1   . ILE C 2 231 ? 386.302 372.567 283.649 1.00 96.97  ? 231 ILE A CD1   1 
ATOM   8433  N  N     . SER C 2 232 ? 384.094 369.194 279.738 1.00 93.24  ? 232 SER A N     1 
ATOM   8434  C  CA    . SER C 2 232 ? 383.984 367.995 278.919 1.00 97.25  ? 232 SER A CA    1 
ATOM   8435  C  C     . SER C 2 232 ? 383.448 368.332 277.538 1.00 99.08  ? 232 SER A C     1 
ATOM   8436  O  O     . SER C 2 232 ? 383.918 367.791 276.531 1.00 105.44 ? 232 SER A O     1 
ATOM   8437  C  CB    . SER C 2 232 ? 383.081 366.975 279.608 1.00 104.69 ? 232 SER A CB    1 
ATOM   8438  O  OG    . SER C 2 232 ? 383.581 366.644 280.888 1.00 112.79 ? 232 SER A OG    1 
ATOM   8439  N  N     . GLN C 2 233 ? 382.458 369.225 277.476 1.00 97.52  ? 233 GLN A N     1 
ATOM   8440  C  CA    . GLN C 2 233 ? 381.936 369.662 276.187 1.00 101.25 ? 233 GLN A CA    1 
ATOM   8441  C  C     . GLN C 2 233 ? 383.016 370.359 275.368 1.00 101.83 ? 233 GLN A C     1 
ATOM   8442  O  O     . GLN C 2 233 ? 383.114 370.147 274.152 1.00 106.80 ? 233 GLN A O     1 
ATOM   8443  C  CB    . GLN C 2 233 ? 380.737 370.586 276.396 1.00 103.63 ? 233 GLN A CB    1 
ATOM   8444  C  CG    . GLN C 2 233 ? 379.485 369.885 276.908 1.00 102.81 ? 233 GLN A CG    1 
ATOM   8445  C  CD    . GLN C 2 233 ? 378.812 369.026 275.854 1.00 106.80 ? 233 GLN A CD    1 
ATOM   8446  O  OE1   . GLN C 2 233 ? 379.200 369.034 274.687 1.00 106.35 ? 233 GLN A OE1   1 
ATOM   8447  N  NE2   . GLN C 2 233 ? 377.795 368.279 276.265 1.00 109.83 ? 233 GLN A NE2   1 
ATOM   8448  N  N     . ILE C 2 234 ? 383.851 371.169 276.028 1.00 103.95 ? 234 ILE A N     1 
ATOM   8449  C  CA    . ILE C 2 234 ? 384.954 371.843 275.338 1.00 101.04 ? 234 ILE A CA    1 
ATOM   8450  C  C     . ILE C 2 234 ? 385.904 370.820 274.720 1.00 102.11 ? 234 ILE A C     1 
ATOM   8451  O  O     . ILE C 2 234 ? 386.236 370.891 273.527 1.00 107.63 ? 234 ILE A O     1 
ATOM   8452  C  CB    . ILE C 2 234 ? 385.697 372.785 276.308 1.00 101.00 ? 234 ILE A CB    1 
ATOM   8453  C  CG1   . ILE C 2 234 ? 384.850 374.025 276.637 1.00 105.15 ? 234 ILE A CG1   1 
ATOM   8454  C  CG2   . ILE C 2 234 ? 387.087 373.187 275.773 1.00 100.06 ? 234 ILE A CG2   1 
ATOM   8455  C  CD1   . ILE C 2 234 ? 384.817 375.117 275.560 1.00 107.87 ? 234 ILE A CD1   1 
ATOM   8456  N  N     . VAL C 2 235 ? 386.350 369.845 275.518 1.00 98.36  ? 235 VAL A N     1 
ATOM   8457  C  CA    . VAL C 2 235 ? 387.355 368.920 274.995 1.00 98.71  ? 235 VAL A CA    1 
ATOM   8458  C  C     . VAL C 2 235 ? 386.746 368.003 273.941 1.00 97.84  ? 235 VAL A C     1 
ATOM   8459  O  O     . VAL C 2 235 ? 387.432 367.599 272.995 1.00 105.55 ? 235 VAL A O     1 
ATOM   8460  C  CB    . VAL C 2 235 ? 388.044 368.110 276.115 1.00 94.96  ? 235 VAL A CB    1 
ATOM   8461  C  CG1   . VAL C 2 235 ? 388.604 369.030 277.194 1.00 102.59 ? 235 VAL A CG1   1 
ATOM   8462  C  CG2   . VAL C 2 235 ? 387.122 367.093 276.749 1.00 99.20  ? 235 VAL A CG2   1 
ATOM   8463  N  N     . SER C 2 236 ? 385.475 367.623 274.099 1.00 108.09 ? 236 SER A N     1 
ATOM   8464  C  CA    . SER C 2 236 ? 384.833 366.790 273.091 1.00 112.33 ? 236 SER A CA    1 
ATOM   8465  C  C     . SER C 2 236 ? 384.699 367.541 271.776 1.00 113.54 ? 236 SER A C     1 
ATOM   8466  O  O     . SER C 2 236 ? 384.897 366.959 270.705 1.00 115.55 ? 236 SER A O     1 
ATOM   8467  C  CB    . SER C 2 236 ? 383.466 366.319 273.581 1.00 117.54 ? 236 SER A CB    1 
ATOM   8468  O  OG    . SER C 2 236 ? 382.572 367.406 273.716 1.00 120.25 ? 236 SER A OG    1 
ATOM   8469  N  N     . SER C 2 237 ? 384.372 368.836 271.835 1.00 114.18 ? 237 SER A N     1 
ATOM   8470  C  CA    . SER C 2 237 ? 384.350 369.641 270.619 1.00 112.23 ? 237 SER A CA    1 
ATOM   8471  C  C     . SER C 2 237 ? 385.733 369.717 269.990 1.00 115.12 ? 237 SER A C     1 
ATOM   8472  O  O     . SER C 2 237 ? 385.864 369.746 268.760 1.00 120.17 ? 237 SER A O     1 
ATOM   8473  C  CB    . SER C 2 237 ? 383.827 371.043 270.926 1.00 110.85 ? 237 SER A CB    1 
ATOM   8474  O  OG    . SER C 2 237 ? 382.554 370.987 271.543 1.00 117.96 ? 237 SER A OG    1 
ATOM   8475  N  N     . ILE C 2 238 ? 386.779 369.755 270.816 1.00 106.62 ? 238 ILE A N     1 
ATOM   8476  C  CA    . ILE C 2 238 ? 388.131 369.829 270.269 1.00 105.60 ? 238 ILE A CA    1 
ATOM   8477  C  C     . ILE C 2 238 ? 388.520 368.516 269.594 1.00 108.58 ? 238 ILE A C     1 
ATOM   8478  O  O     . ILE C 2 238 ? 389.088 368.516 268.496 1.00 111.65 ? 238 ILE A O     1 
ATOM   8479  C  CB    . ILE C 2 238 ? 389.122 370.240 271.373 1.00 102.80 ? 238 ILE A CB    1 
ATOM   8480  C  CG1   . ILE C 2 238 ? 389.006 371.745 271.600 1.00 113.29 ? 238 ILE A CG1   1 
ATOM   8481  C  CG2   . ILE C 2 238 ? 390.572 369.914 271.006 1.00 103.39 ? 238 ILE A CG2   1 
ATOM   8482  C  CD1   . ILE C 2 238 ? 389.372 372.202 272.976 1.00 110.96 ? 238 ILE A CD1   1 
ATOM   8483  N  N     . THR C 2 239 ? 388.222 367.385 270.229 1.00 113.44 ? 239 THR A N     1 
ATOM   8484  C  CA    . THR C 2 239 ? 388.674 366.080 269.752 1.00 105.67 ? 239 THR A CA    1 
ATOM   8485  C  C     . THR C 2 239 ? 387.724 365.421 268.755 1.00 109.66 ? 239 THR A C     1 
ATOM   8486  O  O     . THR C 2 239 ? 388.083 364.384 268.177 1.00 112.62 ? 239 THR A O     1 
ATOM   8487  C  CB    . THR C 2 239 ? 388.886 365.138 270.941 1.00 102.74 ? 239 THR A CB    1 
ATOM   8488  O  OG1   . THR C 2 239 ? 387.729 365.159 271.786 1.00 118.33 ? 239 THR A OG1   1 
ATOM   8489  C  CG2   . THR C 2 239 ? 390.111 365.552 271.746 1.00 107.23 ? 239 THR A CG2   1 
ATOM   8490  N  N     . ALA C 2 240 ? 386.534 365.991 268.530 1.00 108.51 ? 240 ALA A N     1 
ATOM   8491  C  CA    . ALA C 2 240 ? 385.598 365.395 267.586 1.00 106.05 ? 240 ALA A CA    1 
ATOM   8492  C  C     . ALA C 2 240 ? 386.142 365.392 266.167 1.00 107.31 ? 240 ALA A C     1 
ATOM   8493  O  O     . ALA C 2 240 ? 385.748 364.547 265.359 1.00 110.80 ? 240 ALA A O     1 
ATOM   8494  C  CB    . ALA C 2 240 ? 384.264 366.138 267.636 1.00 107.75 ? 240 ALA A CB    1 
ATOM   8495  N  N     . SER C 2 241 ? 387.031 366.327 265.834 1.00 116.59 ? 241 SER A N     1 
ATOM   8496  C  CA    . SER C 2 241 ? 387.654 366.298 264.517 1.00 121.13 ? 241 SER A CA    1 
ATOM   8497  C  C     . SER C 2 241 ? 388.524 365.060 264.347 1.00 121.39 ? 241 SER A C     1 
ATOM   8498  O  O     . SER C 2 241 ? 388.490 364.408 263.297 1.00 118.94 ? 241 SER A O     1 
ATOM   8499  C  CB    . SER C 2 241 ? 388.479 367.559 264.301 1.00 121.72 ? 241 SER A CB    1 
ATOM   8500  O  OG    . SER C 2 241 ? 387.663 368.634 263.871 1.00 119.80 ? 241 SER A OG    1 
ATOM   8501  N  N     . LEU C 2 242 ? 389.317 364.724 265.367 1.00 125.95 ? 242 LEU A N     1 
ATOM   8502  C  CA    . LEU C 2 242 ? 390.106 363.498 265.309 1.00 122.15 ? 242 LEU A CA    1 
ATOM   8503  C  C     . LEU C 2 242 ? 389.212 362.271 265.275 1.00 119.88 ? 242 LEU A C     1 
ATOM   8504  O  O     . LEU C 2 242 ? 389.472 361.326 264.521 1.00 127.68 ? 242 LEU A O     1 
ATOM   8505  C  CB    . LEU C 2 242 ? 391.053 363.411 266.505 1.00 121.29 ? 242 LEU A CB    1 
ATOM   8506  C  CG    . LEU C 2 242 ? 392.363 364.191 266.445 1.00 128.55 ? 242 LEU A CG    1 
ATOM   8507  C  CD1   . LEU C 2 242 ? 392.976 364.238 267.830 1.00 129.88 ? 242 LEU A CD1   1 
ATOM   8508  C  CD2   . LEU C 2 242 ? 393.336 363.561 265.454 1.00 125.53 ? 242 LEU A CD2   1 
ATOM   8509  N  N     . ARG C 2 243 ? 388.153 362.264 266.082 1.00 112.85 ? 243 ARG A N     1 
ATOM   8510  C  CA    . ARG C 2 243 ? 387.351 361.047 266.206 1.00 114.25 ? 243 ARG A CA    1 
ATOM   8511  C  C     . ARG C 2 243 ? 386.412 360.872 265.013 1.00 118.68 ? 243 ARG A C     1 
ATOM   8512  O  O     . ARG C 2 243 ? 386.596 359.969 264.192 1.00 124.60 ? 243 ARG A O     1 
ATOM   8513  C  CB    . ARG C 2 243 ? 386.572 361.073 267.523 1.00 112.60 ? 243 ARG A CB    1 
ATOM   8514  C  CG    . ARG C 2 243 ? 387.445 360.933 268.760 1.00 116.04 ? 243 ARG A CG    1 
ATOM   8515  C  CD    . ARG C 2 243 ? 386.922 361.770 269.907 1.00 112.41 ? 243 ARG A CD    1 
ATOM   8516  N  NE    . ARG C 2 243 ? 385.524 361.475 270.195 1.00 117.11 ? 243 ARG A NE    1 
ATOM   8517  C  CZ    . ARG C 2 243 ? 384.689 362.268 270.856 1.00 119.04 ? 243 ARG A CZ    1 
ATOM   8518  N  NH1   . ARG C 2 243 ? 385.066 363.444 271.338 1.00 115.55 ? 243 ARG A NH1   1 
ATOM   8519  N  NH2   . ARG C 2 243 ? 383.437 361.869 271.044 1.00 119.16 ? 243 ARG A NH2   1 
ATOM   8520  N  N     . PHE C 2 244 ? 385.437 361.761 264.869 1.00 109.60 ? 244 PHE A N     1 
ATOM   8521  C  CA    . PHE C 2 244 ? 384.450 361.660 263.805 1.00 105.21 ? 244 PHE A CA    1 
ATOM   8522  C  C     . PHE C 2 244 ? 384.972 362.297 262.525 1.00 110.13 ? 244 PHE A C     1 
ATOM   8523  O  O     . PHE C 2 244 ? 385.783 363.226 262.553 1.00 115.94 ? 244 PHE A O     1 
ATOM   8524  C  CB    . PHE C 2 244 ? 383.142 362.339 264.210 1.00 102.71 ? 244 PHE A CB    1 
ATOM   8525  C  CG    . PHE C 2 244 ? 382.633 361.926 265.558 1.00 101.48 ? 244 PHE A CG    1 
ATOM   8526  C  CD1   . PHE C 2 244 ? 381.843 360.800 265.696 1.00 104.06 ? 244 PHE A CD1   1 
ATOM   8527  C  CD2   . PHE C 2 244 ? 382.939 362.666 266.686 1.00 109.85 ? 244 PHE A CD2   1 
ATOM   8528  C  CE1   . PHE C 2 244 ? 381.368 360.420 266.932 1.00 108.99 ? 244 PHE A CE1   1 
ATOM   8529  C  CE2   . PHE C 2 244 ? 382.470 362.287 267.925 1.00 111.35 ? 244 PHE A CE2   1 
ATOM   8530  C  CZ    . PHE C 2 244 ? 381.685 361.162 268.049 1.00 108.14 ? 244 PHE A CZ    1 
ATOM   8531  N  N     . ASP C 2 245 ? 384.497 361.783 261.395 1.00 120.39 ? 245 ASP A N     1 
ATOM   8532  C  CA    . ASP C 2 245 ? 384.790 362.407 260.116 1.00 125.54 ? 245 ASP A CA    1 
ATOM   8533  C  C     . ASP C 2 245 ? 384.051 363.737 260.004 1.00 126.00 ? 245 ASP A C     1 
ATOM   8534  O  O     . ASP C 2 245 ? 383.036 363.972 260.666 1.00 125.05 ? 245 ASP A O     1 
ATOM   8535  C  CB    . ASP C 2 245 ? 384.394 361.487 258.962 1.00 127.56 ? 245 ASP A CB    1 
ATOM   8536  C  CG    . ASP C 2 245 ? 382.906 361.210 258.923 1.00 127.71 ? 245 ASP A CG    1 
ATOM   8537  O  OD1   . ASP C 2 245 ? 382.262 361.278 259.990 1.00 127.36 ? 245 ASP A OD1   1 
ATOM   8538  O  OD2   . ASP C 2 245 ? 382.381 360.927 257.826 1.00 128.04 ? 245 ASP A OD2   1 
ATOM   8539  N  N     . GLY C 2 246 ? 384.574 364.614 259.151 1.00 106.21 ? 246 GLY A N     1 
ATOM   8540  C  CA    . GLY C 2 246 ? 384.005 365.942 259.015 1.00 101.23 ? 246 GLY A CA    1 
ATOM   8541  C  C     . GLY C 2 246 ? 384.422 366.597 257.720 1.00 100.92 ? 246 GLY A C     1 
ATOM   8542  O  O     . GLY C 2 246 ? 385.331 366.141 257.023 1.00 102.80 ? 246 GLY A O     1 
ATOM   8543  N  N     . ALA C 2 247 ? 383.730 367.694 257.406 1.00 96.03  ? 247 ALA A N     1 
ATOM   8544  C  CA    . ALA C 2 247 ? 384.046 368.451 256.202 1.00 95.86  ? 247 ALA A CA    1 
ATOM   8545  C  C     . ALA C 2 247 ? 385.418 369.105 256.290 1.00 94.63  ? 247 ALA A C     1 
ATOM   8546  O  O     . ALA C 2 247 ? 386.087 369.273 255.265 1.00 100.37 ? 247 ALA A O     1 
ATOM   8547  C  CB    . ALA C 2 247 ? 382.973 369.509 255.954 1.00 98.89  ? 247 ALA A CB    1 
ATOM   8548  N  N     . LEU C 2 248 ? 385.845 369.488 257.493 1.00 101.15 ? 248 LEU A N     1 
ATOM   8549  C  CA    . LEU C 2 248 ? 387.151 370.104 257.715 1.00 102.98 ? 248 LEU A CA    1 
ATOM   8550  C  C     . LEU C 2 248 ? 387.671 369.594 259.051 1.00 107.56 ? 248 LEU A C     1 
ATOM   8551  O  O     . LEU C 2 248 ? 387.132 369.954 260.102 1.00 110.88 ? 248 LEU A O     1 
ATOM   8552  C  CB    . LEU C 2 248 ? 387.051 371.628 257.712 1.00 103.30 ? 248 LEU A CB    1 
ATOM   8553  C  CG    . LEU C 2 248 ? 387.506 372.337 256.436 1.00 103.22 ? 248 LEU A CG    1 
ATOM   8554  C  CD1   . LEU C 2 248 ? 386.960 373.754 256.403 1.00 107.19 ? 248 LEU A CD1   1 
ATOM   8555  C  CD2   . LEU C 2 248 ? 389.021 372.347 256.326 1.00 107.42 ? 248 LEU A CD2   1 
ATOM   8556  N  N     . ASN C 2 249 ? 388.716 368.771 259.009 1.00 102.24 ? 249 ASN A N     1 
ATOM   8557  C  CA    . ASN C 2 249 ? 389.213 368.060 260.180 1.00 107.43 ? 249 ASN A CA    1 
ATOM   8558  C  C     . ASN C 2 249 ? 390.437 368.766 260.749 1.00 108.94 ? 249 ASN A C     1 
ATOM   8559  O  O     . ASN C 2 249 ? 391.445 368.930 260.054 1.00 105.88 ? 249 ASN A O     1 
ATOM   8560  C  CB    . ASN C 2 249 ? 389.558 366.616 259.818 1.00 106.36 ? 249 ASN A CB    1 
ATOM   8561  C  CG    . ASN C 2 249 ? 388.330 365.795 259.481 1.00 104.34 ? 249 ASN A CG    1 
ATOM   8562  O  OD1   . ASN C 2 249 ? 387.301 365.895 260.149 1.00 101.25 ? 249 ASN A OD1   1 
ATOM   8563  N  ND2   . ASN C 2 249 ? 388.430 364.981 258.437 1.00 107.01 ? 249 ASN A ND2   1 
ATOM   8564  N  N     . VAL C 2 250 ? 390.339 369.174 262.013 1.00 110.95 ? 250 VAL A N     1 
ATOM   8565  C  CA    . VAL C 2 250 ? 391.424 369.815 262.747 1.00 112.83 ? 250 VAL A CA    1 
ATOM   8566  C  C     . VAL C 2 250 ? 392.082 368.773 263.643 1.00 113.05 ? 250 VAL A C     1 
ATOM   8567  O  O     . VAL C 2 250 ? 391.417 368.164 264.490 1.00 109.70 ? 250 VAL A O     1 
ATOM   8568  C  CB    . VAL C 2 250 ? 390.898 370.999 263.579 1.00 115.15 ? 250 VAL A CB    1 
ATOM   8569  C  CG1   . VAL C 2 250 ? 392.044 371.835 264.151 1.00 114.89 ? 250 VAL A CG1   1 
ATOM   8570  C  CG2   . VAL C 2 250 ? 389.970 371.859 262.742 1.00 111.90 ? 250 VAL A CG2   1 
ATOM   8571  N  N     . ASP C 2 251 ? 393.383 368.575 263.461 1.00 136.50 ? 251 ASP A N     1 
ATOM   8572  C  CA    . ASP C 2 251 ? 394.216 367.747 264.322 1.00 133.20 ? 251 ASP A CA    1 
ATOM   8573  C  C     . ASP C 2 251 ? 395.008 368.621 265.288 1.00 136.65 ? 251 ASP A C     1 
ATOM   8574  O  O     . ASP C 2 251 ? 395.009 369.852 265.204 1.00 140.61 ? 251 ASP A O     1 
ATOM   8575  C  CB    . ASP C 2 251 ? 395.166 366.884 263.486 1.00 133.12 ? 251 ASP A CB    1 
ATOM   8576  C  CG    . ASP C 2 251 ? 394.431 365.995 262.508 1.00 137.87 ? 251 ASP A CG    1 
ATOM   8577  O  OD1   . ASP C 2 251 ? 393.187 365.924 262.592 1.00 137.19 ? 251 ASP A OD1   1 
ATOM   8578  O  OD2   . ASP C 2 251 ? 395.095 365.365 261.659 1.00 140.22 ? 251 ASP A OD2   1 
ATOM   8579  N  N     . LEU C 2 252 ? 395.698 367.955 266.216 1.00 126.01 ? 252 LEU A N     1 
ATOM   8580  C  CA    . LEU C 2 252 ? 396.415 368.674 267.264 1.00 129.63 ? 252 LEU A CA    1 
ATOM   8581  C  C     . LEU C 2 252 ? 397.611 369.432 266.705 1.00 129.66 ? 252 LEU A C     1 
ATOM   8582  O  O     . LEU C 2 252 ? 397.940 370.527 267.185 1.00 130.12 ? 252 LEU A O     1 
ATOM   8583  C  CB    . LEU C 2 252 ? 396.869 367.702 268.350 1.00 125.75 ? 252 LEU A CB    1 
ATOM   8584  C  CG    . LEU C 2 252 ? 395.851 366.688 268.876 1.00 124.15 ? 252 LEU A CG    1 
ATOM   8585  C  CD1   . LEU C 2 252 ? 396.401 366.000 270.115 1.00 126.81 ? 252 LEU A CD1   1 
ATOM   8586  C  CD2   . LEU C 2 252 ? 394.503 367.336 269.172 1.00 124.79 ? 252 LEU A CD2   1 
ATOM   8587  N  N     . THR C 2 253 ? 398.284 368.860 265.704 1.00 116.58 ? 253 THR A N     1 
ATOM   8588  C  CA    . THR C 2 253 ? 399.447 369.522 265.125 1.00 119.23 ? 253 THR A CA    1 
ATOM   8589  C  C     . THR C 2 253 ? 399.056 370.841 264.474 1.00 123.29 ? 253 THR A C     1 
ATOM   8590  O  O     . THR C 2 253 ? 399.746 371.851 264.641 1.00 129.02 ? 253 THR A O     1 
ATOM   8591  C  CB    . THR C 2 253 ? 400.125 368.601 264.111 1.00 119.38 ? 253 THR A CB    1 
ATOM   8592  O  OG1   . THR C 2 253 ? 400.110 367.254 264.602 1.00 113.60 ? 253 THR A OG1   1 
ATOM   8593  C  CG2   . THR C 2 253 ? 401.568 369.032 263.870 1.00 119.84 ? 253 THR A CG2   1 
ATOM   8594  N  N     . GLU C 2 254 ? 397.936 370.862 263.749 1.00 121.20 ? 254 GLU A N     1 
ATOM   8595  C  CA    . GLU C 2 254 ? 397.455 372.116 263.178 1.00 125.04 ? 254 GLU A CA    1 
ATOM   8596  C  C     . GLU C 2 254 ? 396.774 373.020 264.200 1.00 117.17 ? 254 GLU A C     1 
ATOM   8597  O  O     . GLU C 2 254 ? 396.751 374.235 263.984 1.00 117.38 ? 254 GLU A O     1 
ATOM   8598  C  CB    . GLU C 2 254 ? 396.520 371.869 261.987 1.00 125.25 ? 254 GLU A CB    1 
ATOM   8599  C  CG    . GLU C 2 254 ? 395.302 371.003 262.207 1.00 121.73 ? 254 GLU A CG    1 
ATOM   8600  C  CD    . GLU C 2 254 ? 394.760 370.447 260.900 1.00 123.66 ? 254 GLU A CD    1 
ATOM   8601  O  OE1   . GLU C 2 254 ? 394.996 371.064 259.840 1.00 121.74 ? 254 GLU A OE1   1 
ATOM   8602  O  OE2   . GLU C 2 254 ? 394.123 369.374 260.927 1.00 121.24 ? 254 GLU A OE2   1 
ATOM   8603  N  N     . PHE C 2 255 ? 396.263 372.483 265.315 1.00 105.84 ? 255 PHE A N     1 
ATOM   8604  C  CA    . PHE C 2 255 ? 395.850 373.354 266.418 1.00 108.98 ? 255 PHE A CA    1 
ATOM   8605  C  C     . PHE C 2 255 ? 397.031 374.170 266.909 1.00 111.71 ? 255 PHE A C     1 
ATOM   8606  O  O     . PHE C 2 255 ? 396.967 375.399 267.017 1.00 114.16 ? 255 PHE A O     1 
ATOM   8607  C  CB    . PHE C 2 255 ? 395.310 372.529 267.589 1.00 106.76 ? 255 PHE A CB    1 
ATOM   8608  C  CG    . PHE C 2 255 ? 393.832 372.318 267.580 1.00 107.17 ? 255 PHE A CG    1 
ATOM   8609  C  CD1   . PHE C 2 255 ? 392.947 373.375 267.700 1.00 110.89 ? 255 PHE A CD1   1 
ATOM   8610  C  CD2   . PHE C 2 255 ? 393.329 371.040 267.482 1.00 109.20 ? 255 PHE A CD2   1 
ATOM   8611  C  CE1   . PHE C 2 255 ? 391.592 373.152 267.697 1.00 114.59 ? 255 PHE A CE1   1 
ATOM   8612  C  CE2   . PHE C 2 255 ? 391.985 370.812 267.479 1.00 112.03 ? 255 PHE A CE2   1 
ATOM   8613  C  CZ    . PHE C 2 255 ? 391.112 371.864 267.587 1.00 114.03 ? 255 PHE A CZ    1 
ATOM   8614  N  N     . GLN C 2 256 ? 398.122 373.474 267.203 1.00 117.76 ? 256 GLN A N     1 
ATOM   8615  C  CA    . GLN C 2 256 ? 399.402 374.103 267.525 1.00 112.19 ? 256 GLN A CA    1 
ATOM   8616  C  C     . GLN C 2 256 ? 399.867 375.088 266.446 1.00 117.42 ? 256 GLN A C     1 
ATOM   8617  O  O     . GLN C 2 256 ? 400.141 376.256 266.759 1.00 119.04 ? 256 GLN A O     1 
ATOM   8618  C  CB    . GLN C 2 256 ? 400.401 372.963 267.826 1.00 115.21 ? 256 GLN A CB    1 
ATOM   8619  C  CG    . GLN C 2 256 ? 401.892 373.226 267.743 1.00 120.23 ? 256 GLN A CG    1 
ATOM   8620  C  CD    . GLN C 2 256 ? 402.396 373.064 266.314 1.00 129.83 ? 256 GLN A CD    1 
ATOM   8621  O  OE1   . GLN C 2 256 ? 402.197 372.030 265.704 1.00 131.86 ? 256 GLN A OE1   1 
ATOM   8622  N  NE2   . GLN C 2 256 ? 402.999 374.109 265.764 1.00 123.85 ? 256 GLN A NE2   1 
ATOM   8623  N  N     . THR C 2 257 ? 399.882 374.671 265.172 1.00 115.22 ? 257 THR A N     1 
ATOM   8624  C  CA    . THR C 2 257 ? 400.415 375.520 264.102 1.00 111.63 ? 257 THR A CA    1 
ATOM   8625  C  C     . THR C 2 257 ? 399.591 376.787 263.915 1.00 110.97 ? 257 THR A C     1 
ATOM   8626  O  O     . THR C 2 257 ? 400.147 377.858 263.649 1.00 112.74 ? 257 THR A O     1 
ATOM   8627  C  CB    . THR C 2 257 ? 400.473 374.740 262.786 1.00 111.15 ? 257 THR A CB    1 
ATOM   8628  O  OG1   . THR C 2 257 ? 401.240 373.542 262.968 1.00 111.48 ? 257 THR A OG1   1 
ATOM   8629  C  CG2   . THR C 2 257 ? 401.099 375.587 261.673 1.00 114.54 ? 257 THR A CG2   1 
ATOM   8630  N  N     . ASN C 2 258 ? 398.267 376.689 264.042 1.00 107.53 ? 258 ASN A N     1 
ATOM   8631  C  CA    . ASN C 2 258 ? 397.408 377.848 263.841 1.00 107.23 ? 258 ASN A CA    1 
ATOM   8632  C  C     . ASN C 2 258 ? 397.411 378.761 265.059 1.00 109.24 ? 258 ASN A C     1 
ATOM   8633  O  O     . ASN C 2 258 ? 397.557 379.981 264.927 1.00 113.46 ? 258 ASN A O     1 
ATOM   8634  C  CB    . ASN C 2 258 ? 395.985 377.389 263.523 1.00 106.59 ? 258 ASN A CB    1 
ATOM   8635  C  CG    . ASN C 2 258 ? 395.827 376.934 262.092 1.00 108.47 ? 258 ASN A CG    1 
ATOM   8636  O  OD1   . ASN C 2 258 ? 395.618 377.744 261.192 1.00 114.75 ? 258 ASN A OD1   1 
ATOM   8637  N  ND2   . ASN C 2 258 ? 395.926 375.631 261.871 1.00 106.77 ? 258 ASN A ND2   1 
ATOM   8638  N  N     . LEU C 2 259 ? 397.250 378.194 266.258 1.00 98.68  ? 259 LEU A N     1 
ATOM   8639  C  CA    . LEU C 2 259 ? 397.021 379.021 267.434 1.00 98.74  ? 259 LEU A CA    1 
ATOM   8640  C  C     . LEU C 2 259 ? 398.299 379.625 268.002 1.00 104.00 ? 259 LEU A C     1 
ATOM   8641  O  O     . LEU C 2 259 ? 398.236 380.715 268.580 1.00 108.83 ? 259 LEU A O     1 
ATOM   8642  C  CB    . LEU C 2 259 ? 396.313 378.202 268.516 1.00 102.03 ? 259 LEU A CB    1 
ATOM   8643  C  CG    . LEU C 2 259 ? 394.841 377.856 268.265 1.00 104.80 ? 259 LEU A CG    1 
ATOM   8644  C  CD1   . LEU C 2 259 ? 394.365 376.800 269.250 1.00 114.06 ? 259 LEU A CD1   1 
ATOM   8645  C  CD2   . LEU C 2 259 ? 393.955 379.093 268.358 1.00 105.98 ? 259 LEU A CD2   1 
ATOM   8646  N  N     . VAL C 2 260 ? 399.447 378.962 267.859 1.00 107.48 ? 260 VAL A N     1 
ATOM   8647  C  CA    . VAL C 2 260 ? 400.656 379.365 268.585 1.00 104.28 ? 260 VAL A CA    1 
ATOM   8648  C  C     . VAL C 2 260 ? 401.598 380.122 267.650 1.00 108.28 ? 260 VAL A C     1 
ATOM   8649  O  O     . VAL C 2 260 ? 402.352 379.478 266.909 1.00 116.80 ? 260 VAL A O     1 
ATOM   8650  C  CB    . VAL C 2 260 ? 401.362 378.142 269.192 1.00 107.12 ? 260 VAL A CB    1 
ATOM   8651  C  CG1   . VAL C 2 260 ? 402.633 378.568 269.934 1.00 105.60 ? 260 VAL A CG1   1 
ATOM   8652  C  CG2   . VAL C 2 260 ? 400.416 377.378 270.119 1.00 112.70 ? 260 VAL A CG2   1 
ATOM   8653  N  N     . PRO C 2 261 ? 401.607 381.477 267.628 1.00 91.27  ? 261 PRO A N     1 
ATOM   8654  C  CA    . PRO C 2 261 ? 402.593 382.172 266.784 1.00 92.94  ? 261 PRO A CA    1 
ATOM   8655  C  C     . PRO C 2 261 ? 404.033 381.960 267.221 1.00 95.31  ? 261 PRO A C     1 
ATOM   8656  O  O     . PRO C 2 261 ? 404.851 381.467 266.437 1.00 97.42  ? 261 PRO A O     1 
ATOM   8657  C  CB    . PRO C 2 261 ? 402.186 383.647 266.903 1.00 88.40  ? 261 PRO A CB    1 
ATOM   8658  C  CG    . PRO C 2 261 ? 401.364 383.734 268.117 1.00 86.12  ? 261 PRO A CG    1 
ATOM   8659  C  CD    . PRO C 2 261 ? 400.656 382.433 268.221 1.00 89.99  ? 261 PRO A CD    1 
ATOM   8660  N  N     . TYR C 2 262 ? 404.343 382.309 268.464 1.00 95.57  ? 262 TYR A N     1 
ATOM   8661  C  CA    . TYR C 2 262 ? 405.678 382.236 269.040 1.00 89.34  ? 262 TYR A CA    1 
ATOM   8662  C  C     . TYR C 2 262 ? 405.741 381.122 270.077 1.00 90.97  ? 262 TYR A C     1 
ATOM   8663  O  O     . TYR C 2 262 ? 404.698 380.664 270.556 1.00 97.76  ? 262 TYR A O     1 
ATOM   8664  C  CB    . TYR C 2 262 ? 406.050 383.580 269.680 1.00 87.62  ? 262 TYR A CB    1 
ATOM   8665  C  CG    . TYR C 2 262 ? 406.002 384.735 268.708 1.00 91.46  ? 262 TYR A CG    1 
ATOM   8666  C  CD1   . TYR C 2 262 ? 407.021 384.932 267.787 1.00 93.12  ? 262 TYR A CD1   1 
ATOM   8667  C  CD2   . TYR C 2 262 ? 404.940 385.625 268.708 1.00 97.15  ? 262 TYR A CD2   1 
ATOM   8668  C  CE1   . TYR C 2 262 ? 406.984 385.984 266.896 1.00 93.45  ? 262 TYR A CE1   1 
ATOM   8669  C  CE2   . TYR C 2 262 ? 404.894 386.680 267.818 1.00 98.43  ? 262 TYR A CE2   1 
ATOM   8670  C  CZ    . TYR C 2 262 ? 405.918 386.854 266.916 1.00 95.92  ? 262 TYR A CZ    1 
ATOM   8671  O  OH    . TYR C 2 262 ? 405.876 387.904 266.029 1.00 95.41  ? 262 TYR A OH    1 
ATOM   8672  N  N     . PRO C 2 263 ? 406.943 380.626 270.422 1.00 94.87  ? 263 PRO A N     1 
ATOM   8673  C  CA    . PRO C 2 263 ? 407.008 379.480 271.351 1.00 100.43 ? 263 PRO A CA    1 
ATOM   8674  C  C     . PRO C 2 263 ? 406.430 379.766 272.724 1.00 105.68 ? 263 PRO A C     1 
ATOM   8675  O  O     . PRO C 2 263 ? 405.800 378.888 273.326 1.00 110.55 ? 263 PRO A O     1 
ATOM   8676  C  CB    . PRO C 2 263 ? 408.513 379.182 271.438 1.00 98.73  ? 263 PRO A CB    1 
ATOM   8677  C  CG    . PRO C 2 263 ? 409.132 379.894 270.301 1.00 102.61 ? 263 PRO A CG    1 
ATOM   8678  C  CD    . PRO C 2 263 ? 408.296 381.096 270.073 1.00 97.83  ? 263 PRO A CD    1 
ATOM   8679  N  N     . ARG C 2 264 ? 406.613 380.985 273.224 1.00 103.83 ? 264 ARG A N     1 
ATOM   8680  C  CA    . ARG C 2 264 ? 406.223 381.346 274.578 1.00 99.79  ? 264 ARG A CA    1 
ATOM   8681  C  C     . ARG C 2 264 ? 404.826 381.950 274.673 1.00 101.14 ? 264 ARG A C     1 
ATOM   8682  O  O     . ARG C 2 264 ? 404.364 382.199 275.792 1.00 105.29 ? 264 ARG A O     1 
ATOM   8683  C  CB    . ARG C 2 264 ? 407.247 382.325 275.157 1.00 100.94 ? 264 ARG A CB    1 
ATOM   8684  C  CG    . ARG C 2 264 ? 408.639 381.719 275.306 1.00 102.48 ? 264 ARG A CG    1 
ATOM   8685  C  CD    . ARG C 2 264 ? 409.659 382.733 275.782 1.00 104.73 ? 264 ARG A CD    1 
ATOM   8686  N  NE    . ARG C 2 264 ? 409.763 382.733 277.241 1.00 102.74 ? 264 ARG A NE    1 
ATOM   8687  C  CZ    . ARG C 2 264 ? 409.456 383.731 278.066 1.00 105.68 ? 264 ARG A CZ    1 
ATOM   8688  N  NH1   . ARG C 2 264 ? 408.968 384.886 277.636 1.00 106.11 ? 264 ARG A NH1   1 
ATOM   8689  N  NH2   . ARG C 2 264 ? 409.638 383.562 279.372 1.00 109.00 ? 264 ARG A NH2   1 
ATOM   8690  N  N     . ILE C 2 265 ? 404.149 382.189 273.545 1.00 95.96  ? 265 ILE A N     1 
ATOM   8691  C  CA    . ILE C 2 265 ? 402.779 382.695 273.525 1.00 98.04  ? 265 ILE A CA    1 
ATOM   8692  C  C     . ILE C 2 265 ? 401.901 381.560 273.017 1.00 100.21 ? 265 ILE A C     1 
ATOM   8693  O  O     . ILE C 2 265 ? 401.671 381.435 271.809 1.00 107.12 ? 265 ILE A O     1 
ATOM   8694  C  CB    . ILE C 2 265 ? 402.661 383.947 272.632 1.00 95.20  ? 265 ILE A CB    1 
ATOM   8695  C  CG1   . ILE C 2 265 ? 403.417 385.131 273.245 1.00 93.51  ? 265 ILE A CG1   1 
ATOM   8696  C  CG2   . ILE C 2 265 ? 401.199 384.333 272.417 1.00 99.50  ? 265 ILE A CG2   1 
ATOM   8697  C  CD1   . ILE C 2 265 ? 404.017 386.050 272.215 1.00 98.49  ? 265 ILE A CD1   1 
ATOM   8698  N  N     . HIS C 2 266 ? 401.435 380.711 273.932 1.00 99.73  ? 266 HIS A N     1 
ATOM   8699  C  CA    . HIS C 2 266 ? 400.696 379.499 273.583 1.00 104.25 ? 266 HIS A CA    1 
ATOM   8700  C  C     . HIS C 2 266 ? 399.571 379.240 274.582 1.00 103.71 ? 266 HIS A C     1 
ATOM   8701  O  O     . HIS C 2 266 ? 399.371 378.116 275.044 1.00 105.13 ? 266 HIS A O     1 
ATOM   8702  C  CB    . HIS C 2 266 ? 401.655 378.315 273.476 1.00 104.32 ? 266 HIS A CB    1 
ATOM   8703  C  CG    . HIS C 2 266 ? 402.440 378.047 274.722 1.00 105.51 ? 266 HIS A CG    1 
ATOM   8704  N  ND1   . HIS C 2 266 ? 403.658 378.640 274.973 1.00 108.12 ? 266 HIS A ND1   1 
ATOM   8705  C  CD2   . HIS C 2 266 ? 402.195 377.231 275.774 1.00 108.22 ? 266 HIS A CD2   1 
ATOM   8706  C  CE1   . HIS C 2 266 ? 404.123 378.212 276.132 1.00 107.07 ? 266 HIS A CE1   1 
ATOM   8707  N  NE2   . HIS C 2 266 ? 403.255 377.356 276.639 1.00 104.94 ? 266 HIS A NE2   1 
ATOM   8708  N  N     . PHE C 2 267 ? 398.805 380.286 274.906 1.00 105.10 ? 267 PHE A N     1 
ATOM   8709  C  CA    . PHE C 2 267 ? 397.742 380.238 275.916 1.00 100.42 ? 267 PHE A CA    1 
ATOM   8710  C  C     . PHE C 2 267 ? 396.431 380.751 275.326 1.00 99.18  ? 267 PHE A C     1 
ATOM   8711  O  O     . PHE C 2 267 ? 396.072 381.919 275.524 1.00 98.94  ? 267 PHE A O     1 
ATOM   8712  C  CB    . PHE C 2 267 ? 398.131 381.060 277.144 1.00 97.65  ? 267 PHE A CB    1 
ATOM   8713  C  CG    . PHE C 2 267 ? 399.387 380.587 277.821 1.00 104.08 ? 267 PHE A CG    1 
ATOM   8714  C  CD1   . PHE C 2 267 ? 400.624 381.075 277.440 1.00 105.88 ? 267 PHE A CD1   1 
ATOM   8715  C  CD2   . PHE C 2 267 ? 399.327 379.667 278.851 1.00 100.01 ? 267 PHE A CD2   1 
ATOM   8716  C  CE1   . PHE C 2 267 ? 401.776 380.645 278.066 1.00 102.10 ? 267 PHE A CE1   1 
ATOM   8717  C  CE2   . PHE C 2 267 ? 400.475 379.234 279.480 1.00 96.20  ? 267 PHE A CE2   1 
ATOM   8718  C  CZ    . PHE C 2 267 ? 401.700 379.724 279.087 1.00 99.25  ? 267 PHE A CZ    1 
ATOM   8719  N  N     . PRO C 2 268 ? 395.687 379.913 274.603 1.00 93.10  ? 268 PRO A N     1 
ATOM   8720  C  CA    . PRO C 2 268 ? 394.361 380.330 274.136 1.00 100.67 ? 268 PRO A CA    1 
ATOM   8721  C  C     . PRO C 2 268 ? 393.321 380.307 275.248 1.00 97.26  ? 268 PRO A C     1 
ATOM   8722  O  O     . PRO C 2 268 ? 393.530 379.747 276.325 1.00 97.48  ? 268 PRO A O     1 
ATOM   8723  C  CB    . PRO C 2 268 ? 394.014 379.302 273.051 1.00 107.94 ? 268 PRO A CB    1 
ATOM   8724  C  CG    . PRO C 2 268 ? 395.263 378.567 272.775 1.00 104.59 ? 268 PRO A CG    1 
ATOM   8725  C  CD    . PRO C 2 268 ? 396.043 378.601 274.037 1.00 99.95  ? 268 PRO A CD    1 
ATOM   8726  N  N     . LEU C 2 269 ? 392.181 380.931 274.950 1.00 101.57 ? 269 LEU A N     1 
ATOM   8727  C  CA    . LEU C 2 269 ? 391.043 381.020 275.859 1.00 96.80  ? 269 LEU A CA    1 
ATOM   8728  C  C     . LEU C 2 269 ? 389.908 380.152 275.336 1.00 104.63 ? 269 LEU A C     1 
ATOM   8729  O  O     . LEU C 2 269 ? 389.469 380.320 274.195 1.00 107.47 ? 269 LEU A O     1 
ATOM   8730  C  CB    . LEU C 2 269 ? 390.562 382.466 275.993 1.00 104.05 ? 269 LEU A CB    1 
ATOM   8731  C  CG    . LEU C 2 269 ? 391.351 383.422 276.891 1.00 110.67 ? 269 LEU A CG    1 
ATOM   8732  C  CD1   . LEU C 2 269 ? 392.748 383.675 276.347 1.00 112.23 ? 269 LEU A CD1   1 
ATOM   8733  C  CD2   . LEU C 2 269 ? 390.591 384.731 277.046 1.00 111.24 ? 269 LEU A CD2   1 
ATOM   8734  N  N     . ALA C 2 270 ? 389.419 379.246 276.178 1.00 111.24 ? 270 ALA A N     1 
ATOM   8735  C  CA    . ALA C 2 270 ? 388.347 378.349 275.779 1.00 109.93 ? 270 ALA A CA    1 
ATOM   8736  C  C     . ALA C 2 270 ? 387.024 379.104 275.670 1.00 111.63 ? 270 ALA A C     1 
ATOM   8737  O  O     . ALA C 2 270 ? 386.846 380.183 276.240 1.00 119.52 ? 270 ALA A O     1 
ATOM   8738  C  CB    . ALA C 2 270 ? 388.219 377.201 276.779 1.00 114.72 ? 270 ALA A CB    1 
ATOM   8739  N  N     . THR C 2 271 ? 386.098 378.540 274.893 1.00 108.95 ? 271 THR A N     1 
ATOM   8740  C  CA    . THR C 2 271 ? 384.744 379.072 274.768 1.00 112.64 ? 271 THR A CA    1 
ATOM   8741  C  C     . THR C 2 271 ? 383.874 378.057 274.041 1.00 118.58 ? 271 THR A C     1 
ATOM   8742  O  O     . THR C 2 271 ? 384.323 377.423 273.083 1.00 123.23 ? 271 THR A O     1 
ATOM   8743  C  CB    . THR C 2 271 ? 384.713 380.417 274.019 1.00 116.16 ? 271 THR A CB    1 
ATOM   8744  O  OG1   . THR C 2 271 ? 385.457 381.408 274.737 1.00 119.31 ? 271 THR A OG1   1 
ATOM   8745  C  CG2   . THR C 2 271 ? 383.282 380.910 273.843 1.00 114.66 ? 271 THR A CG2   1 
ATOM   8746  N  N     . TYR C 2 272 ? 382.636 377.905 274.519 1.00 106.31 ? 272 TYR A N     1 
ATOM   8747  C  CA    . TYR C 2 272 ? 381.599 377.100 273.885 1.00 105.27 ? 272 TYR A CA    1 
ATOM   8748  C  C     . TYR C 2 272 ? 380.376 377.978 273.675 1.00 100.00 ? 272 TYR A C     1 
ATOM   8749  O  O     . TYR C 2 272 ? 380.066 378.838 274.505 1.00 92.79  ? 272 TYR A O     1 
ATOM   8750  C  CB    . TYR C 2 272 ? 381.263 375.840 274.749 1.00 95.15  ? 272 TYR A CB    1 
ATOM   8751  C  CG    . TYR C 2 272 ? 380.316 374.791 274.156 1.00 91.13  ? 272 TYR A CG    1 
ATOM   8752  C  CD1   . TYR C 2 272 ? 378.963 375.051 273.950 1.00 99.91  ? 272 TYR A CD1   1 
ATOM   8753  C  CD2   . TYR C 2 272 ? 380.792 373.542 273.781 1.00 93.59  ? 272 TYR A CD2   1 
ATOM   8754  C  CE1   . TYR C 2 272 ? 378.119 374.105 273.414 1.00 104.86 ? 272 TYR A CE1   1 
ATOM   8755  C  CE2   . TYR C 2 272 ? 379.950 372.588 273.235 1.00 96.24  ? 272 TYR A CE2   1 
ATOM   8756  C  CZ    . TYR C 2 272 ? 378.616 372.875 273.056 1.00 102.09 ? 272 TYR A CZ    1 
ATOM   8757  O  OH    . TYR C 2 272 ? 377.771 371.932 272.517 1.00 110.85 ? 272 TYR A OH    1 
ATOM   8758  N  N     . ALA C 2 273 ? 379.707 377.773 272.543 1.00 103.24 ? 273 ALA A N     1 
ATOM   8759  C  CA    . ALA C 2 273 ? 378.341 378.226 272.343 1.00 101.08 ? 273 ALA A CA    1 
ATOM   8760  C  C     . ALA C 2 273 ? 377.606 377.122 271.595 1.00 108.95 ? 273 ALA A C     1 
ATOM   8761  O  O     . ALA C 2 273 ? 378.254 376.301 270.935 1.00 111.22 ? 273 ALA A O     1 
ATOM   8762  C  CB    . ALA C 2 273 ? 378.288 379.537 271.550 1.00 101.52 ? 273 ALA A CB    1 
ATOM   8763  N  N     . PRO C 2 274 ? 376.265 377.057 271.676 1.00 120.22 ? 274 PRO A N     1 
ATOM   8764  C  CA    . PRO C 2 274 ? 375.366 377.802 272.566 1.00 115.40 ? 274 PRO A CA    1 
ATOM   8765  C  C     . PRO C 2 274 ? 375.436 377.239 273.973 1.00 114.53 ? 274 PRO A C     1 
ATOM   8766  O  O     . PRO C 2 274 ? 375.240 376.036 274.140 1.00 112.84 ? 274 PRO A O     1 
ATOM   8767  C  CB    . PRO C 2 274 ? 373.966 377.559 271.993 1.00 117.23 ? 274 PRO A CB    1 
ATOM   8768  C  CG    . PRO C 2 274 ? 374.131 376.903 270.675 1.00 125.06 ? 274 PRO A CG    1 
ATOM   8769  C  CD    . PRO C 2 274 ? 375.586 376.627 270.445 1.00 120.44 ? 274 PRO A CD    1 
ATOM   8770  N  N     . VAL C 2 275 ? 375.754 378.048 274.979 1.00 117.96 ? 275 VAL A N     1 
ATOM   8771  C  CA    . VAL C 2 275 ? 375.404 377.724 276.362 1.00 119.71 ? 275 VAL A CA    1 
ATOM   8772  C  C     . VAL C 2 275 ? 374.056 378.385 276.633 1.00 118.33 ? 275 VAL A C     1 
ATOM   8773  O  O     . VAL C 2 275 ? 373.928 379.609 276.581 1.00 122.61 ? 275 VAL A O     1 
ATOM   8774  C  CB    . VAL C 2 275 ? 376.482 378.154 277.372 1.00 120.82 ? 275 VAL A CB    1 
ATOM   8775  C  CG1   . VAL C 2 275 ? 377.656 377.189 277.306 1.00 121.43 ? 275 VAL A CG1   1 
ATOM   8776  C  CG2   . VAL C 2 275 ? 376.993 379.584 277.166 1.00 122.05 ? 275 VAL A CG2   1 
ATOM   8777  N  N     . ILE C 2 276 ? 373.030 377.568 276.852 1.00 120.32 ? 276 ILE A N     1 
ATOM   8778  C  CA    . ILE C 2 276 ? 371.664 378.066 276.944 1.00 123.53 ? 276 ILE A CA    1 
ATOM   8779  C  C     . ILE C 2 276 ? 370.831 377.025 277.676 1.00 125.83 ? 276 ILE A C     1 
ATOM   8780  O  O     . ILE C 2 276 ? 371.017 375.819 277.494 1.00 123.13 ? 276 ILE A O     1 
ATOM   8781  C  CB    . ILE C 2 276 ? 371.092 378.387 275.539 1.00 118.36 ? 276 ILE A CB    1 
ATOM   8782  C  CG1   . ILE C 2 276 ? 369.838 379.264 275.634 1.00 121.96 ? 276 ILE A CG1   1 
ATOM   8783  C  CG2   . ILE C 2 276 ? 370.778 377.109 274.767 1.00 116.39 ? 276 ILE A CG2   1 
ATOM   8784  C  CD1   . ILE C 2 276 ? 370.136 380.730 275.860 1.00 121.45 ? 276 ILE A CD1   1 
ATOM   8785  N  N     . SER C 2 277 ? 369.919 377.503 278.514 1.00 140.94 ? 277 SER A N     1 
ATOM   8786  C  CA    . SER C 2 277 ? 368.997 376.618 279.204 1.00 140.00 ? 277 SER A CA    1 
ATOM   8787  C  C     . SER C 2 277 ? 367.944 376.084 278.241 1.00 143.95 ? 277 SER A C     1 
ATOM   8788  O  O     . SER C 2 277 ? 367.604 376.719 277.240 1.00 147.99 ? 277 SER A O     1 
ATOM   8789  C  CB    . SER C 2 277 ? 368.319 377.355 280.356 1.00 140.07 ? 277 SER A CB    1 
ATOM   8790  O  OG    . SER C 2 277 ? 367.194 376.635 280.826 1.00 141.70 ? 277 SER A OG    1 
ATOM   8791  N  N     . ALA C 2 278 ? 367.425 374.896 278.557 1.00 152.27 ? 278 ALA A N     1 
ATOM   8792  C  CA    . ALA C 2 278 ? 366.352 374.319 277.758 1.00 151.80 ? 278 ALA A CA    1 
ATOM   8793  C  C     . ALA C 2 278 ? 365.062 375.122 277.855 1.00 151.29 ? 278 ALA A C     1 
ATOM   8794  O  O     . ALA C 2 278 ? 364.246 375.069 276.928 1.00 149.96 ? 278 ALA A O     1 
ATOM   8795  C  CB    . ALA C 2 278 ? 366.094 372.876 278.190 1.00 149.37 ? 278 ALA A CB    1 
ATOM   8796  N  N     . GLU C 2 279 ? 364.856 375.855 278.952 1.00 167.79 ? 279 GLU A N     1 
ATOM   8797  C  CA    . GLU C 2 279 ? 363.647 376.660 279.094 1.00 167.21 ? 279 GLU A CA    1 
ATOM   8798  C  C     . GLU C 2 279 ? 363.604 377.772 278.052 1.00 166.27 ? 279 GLU A C     1 
ATOM   8799  O  O     . GLU C 2 279 ? 362.567 378.001 277.417 1.00 164.24 ? 279 GLU A O     1 
ATOM   8800  C  CB    . GLU C 2 279 ? 363.578 377.242 280.506 1.00 170.23 ? 279 GLU A CB    1 
ATOM   8801  C  CG    . GLU C 2 279 ? 363.402 376.197 281.597 1.00 171.45 ? 279 GLU A CG    1 
ATOM   8802  C  CD    . GLU C 2 279 ? 363.411 376.797 282.990 1.00 173.07 ? 279 GLU A CD    1 
ATOM   8803  O  OE1   . GLU C 2 279 ? 363.747 377.992 283.125 1.00 172.73 ? 279 GLU A OE1   1 
ATOM   8804  O  OE2   . GLU C 2 279 ? 363.084 376.070 283.951 1.00 173.91 ? 279 GLU A OE2   1 
ATOM   8805  N  N     . LYS C 2 280 ? 364.726 378.470 277.862 1.00 153.37 ? 280 LYS A N     1 
ATOM   8806  C  CA    . LYS C 2 280 ? 364.852 379.524 276.860 1.00 149.63 ? 280 LYS A CA    1 
ATOM   8807  C  C     . LYS C 2 280 ? 365.264 379.009 275.486 1.00 151.12 ? 280 LYS A C     1 
ATOM   8808  O  O     . LYS C 2 280 ? 365.251 379.788 274.527 1.00 152.32 ? 280 LYS A O     1 
ATOM   8809  C  CB    . LYS C 2 280 ? 365.876 380.579 277.322 1.00 146.71 ? 280 LYS A CB    1 
ATOM   8810  C  CG    . LYS C 2 280 ? 365.344 381.812 278.094 1.00 150.60 ? 280 LYS A CG    1 
ATOM   8811  C  CD    . LYS C 2 280 ? 364.291 382.670 277.360 1.00 150.62 ? 280 LYS A CD    1 
ATOM   8812  C  CE    . LYS C 2 280 ? 363.705 383.740 278.279 1.00 147.47 ? 280 LYS A CE    1 
ATOM   8813  N  NZ    . LYS C 2 280 ? 362.483 384.377 277.704 1.00 142.92 ? 280 LYS A NZ    1 
ATOM   8814  N  N     . ALA C 2 281 ? 365.636 377.731 275.361 1.00 157.97 ? 281 ALA A N     1 
ATOM   8815  C  CA    . ALA C 2 281 ? 366.068 377.205 274.071 1.00 155.36 ? 281 ALA A CA    1 
ATOM   8816  C  C     . ALA C 2 281 ? 364.958 377.206 273.028 1.00 154.60 ? 281 ALA A C     1 
ATOM   8817  O  O     . ALA C 2 281 ? 365.256 377.241 271.829 1.00 151.63 ? 281 ALA A O     1 
ATOM   8818  C  CB    . ALA C 2 281 ? 366.601 375.783 274.241 1.00 154.84 ? 281 ALA A CB    1 
ATOM   8819  N  N     . TYR C 2 282 ? 363.693 377.171 273.447 1.00 163.97 ? 282 TYR A N     1 
ATOM   8820  C  CA    . TYR C 2 282 ? 362.594 377.107 272.489 1.00 162.33 ? 282 TYR A CA    1 
ATOM   8821  C  C     . TYR C 2 282 ? 362.391 378.429 271.761 1.00 165.57 ? 282 TYR A C     1 
ATOM   8822  O  O     . TYR C 2 282 ? 361.946 378.431 270.608 1.00 169.62 ? 282 TYR A O     1 
ATOM   8823  C  CB    . TYR C 2 282 ? 361.283 376.712 273.185 1.00 162.34 ? 282 TYR A CB    1 
ATOM   8824  C  CG    . TYR C 2 282 ? 361.148 375.270 273.675 1.00 163.62 ? 282 TYR A CG    1 
ATOM   8825  C  CD1   . TYR C 2 282 ? 362.248 374.427 273.827 1.00 161.92 ? 282 TYR A CD1   1 
ATOM   8826  C  CD2   . TYR C 2 282 ? 359.896 374.759 273.992 1.00 164.33 ? 282 TYR A CD2   1 
ATOM   8827  C  CE1   . TYR C 2 282 ? 362.100 373.129 274.274 1.00 161.73 ? 282 TYR A CE1   1 
ATOM   8828  C  CE2   . TYR C 2 282 ? 359.741 373.461 274.440 1.00 164.11 ? 282 TYR A CE2   1 
ATOM   8829  C  CZ    . TYR C 2 282 ? 360.846 372.651 274.579 1.00 163.35 ? 282 TYR A CZ    1 
ATOM   8830  O  OH    . TYR C 2 282 ? 360.696 371.359 275.025 1.00 164.17 ? 282 TYR A OH    1 
ATOM   8831  N  N     . HIS C 2 283 ? 362.704 379.552 272.406 1.00 166.91 ? 283 HIS A N     1 
ATOM   8832  C  CA    . HIS C 2 283 ? 362.412 380.855 271.820 1.00 164.53 ? 283 HIS A CA    1 
ATOM   8833  C  C     . HIS C 2 283 ? 363.421 381.226 270.738 1.00 165.62 ? 283 HIS A C     1 
ATOM   8834  O  O     . HIS C 2 283 ? 363.038 381.671 269.651 1.00 167.76 ? 283 HIS A O     1 
ATOM   8835  C  CB    . HIS C 2 283 ? 362.387 381.919 272.918 1.00 165.05 ? 283 HIS A CB    1 
ATOM   8836  C  CG    . HIS C 2 283 ? 361.206 381.813 273.832 1.00 166.43 ? 283 HIS A CG    1 
ATOM   8837  N  ND1   . HIS C 2 283 ? 361.155 380.915 274.877 1.00 165.78 ? 283 HIS A ND1   1 
ATOM   8838  C  CD2   . HIS C 2 283 ? 360.032 382.487 273.858 1.00 166.26 ? 283 HIS A CD2   1 
ATOM   8839  C  CE1   . HIS C 2 283 ? 360.002 381.042 275.508 1.00 164.22 ? 283 HIS A CE1   1 
ATOM   8840  N  NE2   . HIS C 2 283 ? 359.302 381.989 274.909 1.00 165.18 ? 283 HIS A NE2   1 
ATOM   8841  N  N     . GLU C 2 284 ? 364.711 381.050 271.017 1.00 161.93 ? 284 GLU A N     1 
ATOM   8842  C  CA    . GLU C 2 284 ? 365.757 381.514 270.118 1.00 162.19 ? 284 GLU A CA    1 
ATOM   8843  C  C     . GLU C 2 284 ? 366.014 380.492 269.008 1.00 162.71 ? 284 GLU A C     1 
ATOM   8844  O  O     . GLU C 2 284 ? 365.812 379.285 269.169 1.00 163.21 ? 284 GLU A O     1 
ATOM   8845  C  CB    . GLU C 2 284 ? 367.034 381.804 270.908 1.00 161.81 ? 284 GLU A CB    1 
ATOM   8846  C  CG    . GLU C 2 284 ? 368.142 382.475 270.103 1.00 162.34 ? 284 GLU A CG    1 
ATOM   8847  C  CD    . GLU C 2 284 ? 369.312 382.902 270.966 1.00 163.06 ? 284 GLU A CD    1 
ATOM   8848  O  OE1   . GLU C 2 284 ? 369.091 383.663 271.932 1.00 164.06 ? 284 GLU A OE1   1 
ATOM   8849  O  OE2   . GLU C 2 284 ? 370.454 382.495 270.672 1.00 161.11 ? 284 GLU A OE2   1 
ATOM   8850  N  N     . GLN C 2 285 ? 366.473 381.001 267.863 1.00 154.92 ? 285 GLN A N     1 
ATOM   8851  C  CA    . GLN C 2 285 ? 366.699 380.202 266.662 1.00 155.09 ? 285 GLN A CA    1 
ATOM   8852  C  C     . GLN C 2 285 ? 367.957 379.345 266.797 1.00 153.97 ? 285 GLN A C     1 
ATOM   8853  O  O     . GLN C 2 285 ? 367.925 378.147 266.505 1.00 156.02 ? 285 GLN A O     1 
ATOM   8854  C  CB    . GLN C 2 285 ? 366.807 381.144 265.449 1.00 153.63 ? 285 GLN A CB    1 
ATOM   8855  C  CG    . GLN C 2 285 ? 367.430 380.610 264.146 1.00 154.99 ? 285 GLN A CG    1 
ATOM   8856  C  CD    . GLN C 2 285 ? 366.728 379.377 263.582 1.00 154.99 ? 285 GLN A CD    1 
ATOM   8857  O  OE1   . GLN C 2 285 ? 366.626 378.341 264.228 1.00 154.41 ? 285 GLN A OE1   1 
ATOM   8858  N  NE2   . GLN C 2 285 ? 366.242 379.496 262.349 1.00 155.36 ? 285 GLN A NE2   1 
ATOM   8859  N  N     . LEU C 2 286 ? 369.052 379.941 267.277 1.00 131.97 ? 286 LEU A N     1 
ATOM   8860  C  CA    . LEU C 2 286 ? 370.375 379.309 267.368 1.00 128.58 ? 286 LEU A CA    1 
ATOM   8861  C  C     . LEU C 2 286 ? 370.896 378.923 265.981 1.00 131.20 ? 286 LEU A C     1 
ATOM   8862  O  O     . LEU C 2 286 ? 371.160 377.754 265.690 1.00 136.35 ? 286 LEU A O     1 
ATOM   8863  C  CB    . LEU C 2 286 ? 370.378 378.078 268.292 1.00 131.87 ? 286 LEU A CB    1 
ATOM   8864  C  CG    . LEU C 2 286 ? 370.103 378.185 269.799 1.00 134.26 ? 286 LEU A CG    1 
ATOM   8865  C  CD1   . LEU C 2 286 ? 371.111 379.099 270.491 1.00 132.78 ? 286 LEU A CD1   1 
ATOM   8866  C  CD2   . LEU C 2 286 ? 368.667 378.603 270.102 1.00 135.80 ? 286 LEU A CD2   1 
ATOM   8867  N  N     . SER C 2 287 ? 371.047 379.935 265.125 1.00 115.85 ? 287 SER A N     1 
ATOM   8868  C  CA    . SER C 2 287 ? 371.684 379.756 263.828 1.00 113.88 ? 287 SER A CA    1 
ATOM   8869  C  C     . SER C 2 287 ? 373.191 379.959 263.949 1.00 110.39 ? 287 SER A C     1 
ATOM   8870  O  O     . SER C 2 287 ? 373.724 380.319 265.008 1.00 113.66 ? 287 SER A O     1 
ATOM   8871  C  CB    . SER C 2 287 ? 371.106 380.718 262.794 1.00 114.25 ? 287 SER A CB    1 
ATOM   8872  O  OG    . SER C 2 287 ? 371.452 380.303 261.483 1.00 117.01 ? 287 SER A OG    1 
ATOM   8873  N  N     . VAL C 2 288 ? 373.878 379.731 262.827 1.00 103.95 ? 288 VAL A N     1 
ATOM   8874  C  CA    . VAL C 2 288 ? 375.333 379.822 262.789 1.00 104.73 ? 288 VAL A CA    1 
ATOM   8875  C  C     . VAL C 2 288 ? 375.786 381.239 263.122 1.00 106.98 ? 288 VAL A C     1 
ATOM   8876  O  O     . VAL C 2 288 ? 376.756 381.438 263.864 1.00 112.56 ? 288 VAL A O     1 
ATOM   8877  C  CB    . VAL C 2 288 ? 375.847 379.357 261.415 1.00 104.65 ? 288 VAL A CB    1 
ATOM   8878  C  CG1   . VAL C 2 288 ? 377.321 379.708 261.224 1.00 107.22 ? 288 VAL A CG1   1 
ATOM   8879  C  CG2   . VAL C 2 288 ? 375.631 377.854 261.255 1.00 104.85 ? 288 VAL A CG2   1 
ATOM   8880  N  N     . ALA C 2 289 ? 375.087 382.243 262.588 1.00 106.03 ? 289 ALA A N     1 
ATOM   8881  C  CA    . ALA C 2 289 ? 375.445 383.628 262.869 1.00 105.84 ? 289 ALA A CA    1 
ATOM   8882  C  C     . ALA C 2 289 ? 375.279 383.959 264.348 1.00 112.46 ? 289 ALA A C     1 
ATOM   8883  O  O     . ALA C 2 289 ? 376.146 384.610 264.944 1.00 112.68 ? 289 ALA A O     1 
ATOM   8884  C  CB    . ALA C 2 289 ? 374.601 384.568 262.011 1.00 100.81 ? 289 ALA A CB    1 
ATOM   8885  N  N     . GLU C 2 290 ? 374.183 383.503 264.964 1.00 124.34 ? 290 GLU A N     1 
ATOM   8886  C  CA    . GLU C 2 290 ? 373.957 383.796 266.377 1.00 115.28 ? 290 GLU A CA    1 
ATOM   8887  C  C     . GLU C 2 290 ? 375.003 383.132 267.261 1.00 112.77 ? 290 GLU A C     1 
ATOM   8888  O  O     . GLU C 2 290 ? 375.528 383.763 268.185 1.00 118.33 ? 290 GLU A O     1 
ATOM   8889  C  CB    . GLU C 2 290 ? 372.554 383.365 266.811 1.00 119.57 ? 290 GLU A CB    1 
ATOM   8890  C  CG    . GLU C 2 290 ? 371.412 384.174 266.207 1.00 122.87 ? 290 GLU A CG    1 
ATOM   8891  C  CD    . GLU C 2 290 ? 370.972 383.665 264.850 1.00 127.52 ? 290 GLU A CD    1 
ATOM   8892  O  OE1   . GLU C 2 290 ? 371.424 384.223 263.829 1.00 128.55 ? 290 GLU A OE1   1 
ATOM   8893  O  OE2   . GLU C 2 290 ? 370.161 382.717 264.804 1.00 125.46 ? 290 GLU A OE2   1 
ATOM   8894  N  N     . ILE C 2 291 ? 375.315 381.857 267.008 1.00 108.64 ? 291 ILE A N     1 
ATOM   8895  C  CA    . ILE C 2 291 ? 376.294 381.184 267.862 1.00 110.89 ? 291 ILE A CA    1 
ATOM   8896  C  C     . ILE C 2 291 ? 377.681 381.787 267.656 1.00 113.11 ? 291 ILE A C     1 
ATOM   8897  O  O     . ILE C 2 291 ? 378.453 381.940 268.612 1.00 118.10 ? 291 ILE A O     1 
ATOM   8898  C  CB    . ILE C 2 291 ? 376.286 379.655 267.636 1.00 110.37 ? 291 ILE A CB    1 
ATOM   8899  C  CG1   . ILE C 2 291 ? 376.736 379.281 266.213 1.00 117.02 ? 291 ILE A CG1   1 
ATOM   8900  C  CG2   . ILE C 2 291 ? 374.880 379.115 267.947 1.00 112.96 ? 291 ILE A CG2   1 
ATOM   8901  C  CD1   . ILE C 2 291 ? 376.617 377.810 265.844 1.00 116.96 ? 291 ILE A CD1   1 
ATOM   8902  N  N     . THR C 2 292 ? 378.012 382.162 266.415 1.00 103.47 ? 292 THR A N     1 
ATOM   8903  C  CA    . THR C 2 292 ? 379.304 382.787 266.158 1.00 94.51  ? 292 THR A CA    1 
ATOM   8904  C  C     . THR C 2 292 ? 379.412 384.134 266.862 1.00 102.26 ? 292 THR A C     1 
ATOM   8905  O  O     . THR C 2 292 ? 380.464 384.468 267.416 1.00 111.04 ? 292 THR A O     1 
ATOM   8906  C  CB    . THR C 2 292 ? 379.512 382.945 264.652 1.00 99.55  ? 292 THR A CB    1 
ATOM   8907  O  OG1   . THR C 2 292 ? 379.337 381.678 264.006 1.00 108.13 ? 292 THR A OG1   1 
ATOM   8908  C  CG2   . THR C 2 292 ? 380.906 383.456 264.356 1.00 104.58 ? 292 THR A CG2   1 
ATOM   8909  N  N     . ASN C 2 293 ? 378.335 384.922 266.850 1.00 109.06 ? 293 ASN A N     1 
ATOM   8910  C  CA    . ASN C 2 293 ? 378.344 386.185 267.580 1.00 106.43 ? 293 ASN A CA    1 
ATOM   8911  C  C     . ASN C 2 293 ? 378.446 385.953 269.082 1.00 106.49 ? 293 ASN A C     1 
ATOM   8912  O  O     . ASN C 2 293 ? 379.132 386.703 269.786 1.00 103.78 ? 293 ASN A O     1 
ATOM   8913  C  CB    . ASN C 2 293 ? 377.091 386.991 267.248 1.00 103.38 ? 293 ASN A CB    1 
ATOM   8914  C  CG    . ASN C 2 293 ? 377.234 387.782 265.967 1.00 108.01 ? 293 ASN A CG    1 
ATOM   8915  O  OD1   . ASN C 2 293 ? 377.753 388.897 265.969 1.00 107.74 ? 293 ASN A OD1   1 
ATOM   8916  N  ND2   . ASN C 2 293 ? 376.779 387.206 264.861 1.00 116.61 ? 293 ASN A ND2   1 
ATOM   8917  N  N     . ALA C 2 294 ? 377.768 384.922 269.591 1.00 110.98 ? 294 ALA A N     1 
ATOM   8918  C  CA    . ALA C 2 294 ? 377.832 384.621 271.016 1.00 104.84 ? 294 ALA A CA    1 
ATOM   8919  C  C     . ALA C 2 294 ? 379.230 384.199 271.441 1.00 104.27 ? 294 ALA A C     1 
ATOM   8920  O  O     . ALA C 2 294 ? 379.620 384.431 272.591 1.00 108.02 ? 294 ALA A O     1 
ATOM   8921  C  CB    . ALA C 2 294 ? 376.826 383.525 271.367 1.00 111.64 ? 294 ALA A CB    1 
ATOM   8922  N  N     . CYS C 2 295 ? 379.988 383.565 270.541 1.00 118.51 ? 295 CYS A N     1 
ATOM   8923  C  CA    . CYS C 2 295 ? 381.341 383.134 270.885 1.00 116.87 ? 295 CYS A CA    1 
ATOM   8924  C  C     . CYS C 2 295 ? 382.240 384.316 271.230 1.00 116.34 ? 295 CYS A C     1 
ATOM   8925  O  O     . CYS C 2 295 ? 383.019 384.252 272.186 1.00 125.27 ? 295 CYS A O     1 
ATOM   8926  C  CB    . CYS C 2 295 ? 381.954 382.336 269.735 1.00 118.50 ? 295 CYS A CB    1 
ATOM   8927  S  SG    . CYS C 2 295 ? 381.490 380.598 269.702 1.00 140.01 ? 295 CYS A SG    1 
ATOM   8928  N  N     . PHE C 2 296 ? 382.140 385.403 270.471 1.00 99.30  ? 296 PHE A N     1 
ATOM   8929  C  CA    . PHE C 2 296 ? 383.051 386.533 270.605 1.00 98.19  ? 296 PHE A CA    1 
ATOM   8930  C  C     . PHE C 2 296 ? 382.626 387.548 271.660 1.00 102.33 ? 296 PHE A C     1 
ATOM   8931  O  O     . PHE C 2 296 ? 383.351 388.526 271.872 1.00 103.45 ? 296 PHE A O     1 
ATOM   8932  C  CB    . PHE C 2 296 ? 383.205 387.233 269.252 1.00 96.23  ? 296 PHE A CB    1 
ATOM   8933  C  CG    . PHE C 2 296 ? 384.139 386.528 268.319 1.00 99.97  ? 296 PHE A CG    1 
ATOM   8934  C  CD1   . PHE C 2 296 ? 383.721 385.422 267.602 1.00 105.62 ? 296 PHE A CD1   1 
ATOM   8935  C  CD2   . PHE C 2 296 ? 385.436 386.976 268.156 1.00 99.64  ? 296 PHE A CD2   1 
ATOM   8936  C  CE1   . PHE C 2 296 ? 384.583 384.772 266.745 1.00 104.95 ? 296 PHE A CE1   1 
ATOM   8937  C  CE2   . PHE C 2 296 ? 386.298 386.333 267.299 1.00 99.74  ? 296 PHE A CE2   1 
ATOM   8938  C  CZ    . PHE C 2 296 ? 385.873 385.229 266.592 1.00 102.94 ? 296 PHE A CZ    1 
ATOM   8939  N  N     . GLU C 2 297 ? 381.492 387.352 272.329 1.00 119.94 ? 297 GLU A N     1 
ATOM   8940  C  CA    . GLU C 2 297 ? 381.092 388.290 273.366 1.00 114.67 ? 297 GLU A CA    1 
ATOM   8941  C  C     . GLU C 2 297 ? 382.040 388.162 274.561 1.00 117.41 ? 297 GLU A C     1 
ATOM   8942  O  O     . GLU C 2 297 ? 382.550 387.069 274.824 1.00 123.53 ? 297 GLU A O     1 
ATOM   8943  C  CB    . GLU C 2 297 ? 379.653 388.015 273.818 1.00 117.99 ? 297 GLU A CB    1 
ATOM   8944  C  CG    . GLU C 2 297 ? 378.519 388.307 272.812 1.00 121.78 ? 297 GLU A CG    1 
ATOM   8945  C  CD    . GLU C 2 297 ? 378.580 389.674 272.140 1.00 127.27 ? 297 GLU A CD    1 
ATOM   8946  O  OE1   . GLU C 2 297 ? 379.186 390.607 272.706 1.00 124.93 ? 297 GLU A OE1   1 
ATOM   8947  O  OE2   . GLU C 2 297 ? 378.013 389.812 271.036 1.00 131.41 ? 297 GLU A OE2   1 
ATOM   8948  N  N     . PRO C 2 298 ? 382.311 389.248 275.302 1.00 113.80 ? 298 PRO A N     1 
ATOM   8949  C  CA    . PRO C 2 298 ? 383.159 389.089 276.497 1.00 112.35 ? 298 PRO A CA    1 
ATOM   8950  C  C     . PRO C 2 298 ? 382.530 388.232 277.580 1.00 113.90 ? 298 PRO A C     1 
ATOM   8951  O  O     . PRO C 2 298 ? 383.254 387.561 278.325 1.00 114.52 ? 298 PRO A O     1 
ATOM   8952  C  CB    . PRO C 2 298 ? 383.367 390.532 276.982 1.00 112.77 ? 298 PRO A CB    1 
ATOM   8953  C  CG    . PRO C 2 298 ? 382.997 391.392 275.846 1.00 115.62 ? 298 PRO A CG    1 
ATOM   8954  C  CD    . PRO C 2 298 ? 381.922 390.662 275.128 1.00 116.04 ? 298 PRO A CD    1 
ATOM   8955  N  N     . ALA C 2 299 ? 381.199 388.238 277.691 1.00 113.44 ? 299 ALA A N     1 
ATOM   8956  C  CA    . ALA C 2 299 ? 380.543 387.585 278.818 1.00 112.80 ? 299 ALA A CA    1 
ATOM   8957  C  C     . ALA C 2 299 ? 380.679 386.068 278.767 1.00 114.47 ? 299 ALA A C     1 
ATOM   8958  O  O     . ALA C 2 299 ? 380.795 385.428 279.819 1.00 114.60 ? 299 ALA A O     1 
ATOM   8959  C  CB    . ALA C 2 299 ? 379.067 387.979 278.860 1.00 110.69 ? 299 ALA A CB    1 
ATOM   8960  N  N     . ASN C 2 300 ? 380.677 385.479 277.573 1.00 108.75 ? 300 ASN A N     1 
ATOM   8961  C  CA    . ASN C 2 300 ? 380.678 384.029 277.420 1.00 111.77 ? 300 ASN A CA    1 
ATOM   8962  C  C     . ASN C 2 300 ? 382.075 383.420 277.358 1.00 111.58 ? 300 ASN A C     1 
ATOM   8963  O  O     . ASN C 2 300 ? 382.193 382.224 277.072 1.00 113.69 ? 300 ASN A O     1 
ATOM   8964  C  CB    . ASN C 2 300 ? 379.893 383.633 276.167 1.00 113.21 ? 300 ASN A CB    1 
ATOM   8965  C  CG    . ASN C 2 300 ? 378.601 384.410 276.020 1.00 118.93 ? 300 ASN A CG    1 
ATOM   8966  O  OD1   . ASN C 2 300 ? 377.875 384.614 276.992 1.00 118.59 ? 300 ASN A OD1   1 
ATOM   8967  N  ND2   . ASN C 2 300 ? 378.297 384.832 274.801 1.00 119.68 ? 300 ASN A ND2   1 
ATOM   8968  N  N     . GLN C 2 301 ? 383.128 384.195 277.607 1.00 105.40 ? 301 GLN A N     1 
ATOM   8969  C  CA    . GLN C 2 301 ? 384.464 383.621 277.698 1.00 108.06 ? 301 GLN A CA    1 
ATOM   8970  C  C     . GLN C 2 301 ? 384.614 382.854 279.005 1.00 110.19 ? 301 GLN A C     1 
ATOM   8971  O  O     . GLN C 2 301 ? 384.129 383.287 280.053 1.00 114.40 ? 301 GLN A O     1 
ATOM   8972  C  CB    . GLN C 2 301 ? 385.529 384.717 277.618 1.00 107.72 ? 301 GLN A CB    1 
ATOM   8973  C  CG    . GLN C 2 301 ? 385.393 385.676 276.440 1.00 110.23 ? 301 GLN A CG    1 
ATOM   8974  C  CD    . GLN C 2 301 ? 385.403 384.967 275.102 1.00 118.91 ? 301 GLN A CD    1 
ATOM   8975  O  OE1   . GLN C 2 301 ? 386.317 384.199 274.805 1.00 122.41 ? 301 GLN A OE1   1 
ATOM   8976  N  NE2   . GLN C 2 301 ? 384.387 385.220 274.285 1.00 123.64 ? 301 GLN A NE2   1 
ATOM   8977  N  N     . MET C 2 302 ? 385.309 381.716 278.945 1.00 112.38 ? 302 MET A N     1 
ATOM   8978  C  CA    . MET C 2 302 ? 385.589 380.916 280.136 1.00 113.26 ? 302 MET A CA    1 
ATOM   8979  C  C     . MET C 2 302 ? 386.810 381.408 280.910 1.00 116.86 ? 302 MET A C     1 
ATOM   8980  O  O     . MET C 2 302 ? 387.277 380.688 281.799 1.00 121.57 ? 302 MET A O     1 
ATOM   8981  C  CB    . MET C 2 302 ? 385.796 379.426 279.804 1.00 114.68 ? 302 MET A CB    1 
ATOM   8982  C  CG    . MET C 2 302 ? 385.039 378.819 278.615 1.00 121.28 ? 302 MET A CG    1 
ATOM   8983  S  SD    . MET C 2 302 ? 383.311 378.459 278.962 1.00 131.01 ? 302 MET A SD    1 
ATOM   8984  C  CE    . MET C 2 302 ? 383.352 376.670 279.022 1.00 114.58 ? 302 MET A CE    1 
ATOM   8985  N  N     . VAL C 2 303 ? 387.343 382.588 280.590 1.00 110.81 ? 303 VAL A N     1 
ATOM   8986  C  CA    . VAL C 2 303 ? 388.394 383.235 281.364 1.00 111.62 ? 303 VAL A CA    1 
ATOM   8987  C  C     . VAL C 2 303 ? 387.947 384.661 281.638 1.00 115.61 ? 303 VAL A C     1 
ATOM   8988  O  O     . VAL C 2 303 ? 387.498 385.360 280.724 1.00 121.12 ? 303 VAL A O     1 
ATOM   8989  C  CB    . VAL C 2 303 ? 389.748 383.219 280.630 1.00 108.01 ? 303 VAL A CB    1 
ATOM   8990  C  CG1   . VAL C 2 303 ? 390.882 383.527 281.598 1.00 108.42 ? 303 VAL A CG1   1 
ATOM   8991  C  CG2   . VAL C 2 303 ? 389.970 381.875 279.949 1.00 106.34 ? 303 VAL A CG2   1 
ATOM   8992  N  N     . LYS C 2 304 ? 388.067 385.094 282.894 1.00 120.63 ? 304 LYS A N     1 
ATOM   8993  C  CA    . LYS C 2 304 ? 387.645 386.439 283.291 1.00 119.96 ? 304 LYS A CA    1 
ATOM   8994  C  C     . LYS C 2 304 ? 388.677 387.451 282.792 1.00 123.20 ? 304 LYS A C     1 
ATOM   8995  O  O     . LYS C 2 304 ? 389.502 387.985 283.537 1.00 124.17 ? 304 LYS A O     1 
ATOM   8996  C  CB    . LYS C 2 304 ? 387.458 386.524 284.801 1.00 122.58 ? 304 LYS A CB    1 
ATOM   8997  C  CG    . LYS C 2 304 ? 386.085 386.083 285.298 1.00 123.47 ? 304 LYS A CG    1 
ATOM   8998  C  CD    . LYS C 2 304 ? 385.269 387.264 285.804 1.00 121.50 ? 304 LYS A CD    1 
ATOM   8999  C  CE    . LYS C 2 304 ? 383.811 386.889 285.988 1.00 126.61 ? 304 LYS A CE    1 
ATOM   9000  N  NZ    . LYS C 2 304 ? 383.081 387.878 286.828 1.00 125.93 ? 304 LYS A NZ    1 
ATOM   9001  N  N     . CYS C 2 305 ? 388.623 387.698 281.485 1.00 120.75 ? 305 CYS A N     1 
ATOM   9002  C  CA    . CYS C 2 305 ? 389.505 388.651 280.819 1.00 118.29 ? 305 CYS A CA    1 
ATOM   9003  C  C     . CYS C 2 305 ? 388.724 389.266 279.673 1.00 118.80 ? 305 CYS A C     1 
ATOM   9004  O  O     . CYS C 2 305 ? 388.326 388.552 278.748 1.00 122.05 ? 305 CYS A O     1 
ATOM   9005  C  CB    . CYS C 2 305 ? 390.775 387.976 280.294 1.00 115.05 ? 305 CYS A CB    1 
ATOM   9006  S  SG    . CYS C 2 305 ? 391.798 387.178 281.546 1.00 135.53 ? 305 CYS A SG    1 
ATOM   9007  N  N     . ASP C 2 306 ? 388.504 390.570 279.729 1.00 116.56 ? 306 ASP A N     1 
ATOM   9008  C  CA    . ASP C 2 306 ? 387.772 391.239 278.664 1.00 118.51 ? 306 ASP A CA    1 
ATOM   9009  C  C     . ASP C 2 306 ? 388.634 391.252 277.403 1.00 119.47 ? 306 ASP A C     1 
ATOM   9010  O  O     . ASP C 2 306 ? 389.709 391.868 277.422 1.00 121.34 ? 306 ASP A O     1 
ATOM   9011  C  CB    . ASP C 2 306 ? 387.424 392.663 279.080 1.00 116.69 ? 306 ASP A CB    1 
ATOM   9012  C  CG    . ASP C 2 306 ? 386.294 393.252 278.261 1.00 124.19 ? 306 ASP A CG    1 
ATOM   9013  O  OD1   . ASP C 2 306 ? 386.008 392.724 277.166 1.00 128.63 ? 306 ASP A OD1   1 
ATOM   9014  O  OD2   . ASP C 2 306 ? 385.693 394.249 278.711 1.00 121.95 ? 306 ASP A OD2   1 
ATOM   9015  N  N     . PRO C 2 307 ? 388.225 390.616 276.291 1.00 113.15 ? 307 PRO A N     1 
ATOM   9016  C  CA    . PRO C 2 307 ? 389.058 390.697 275.077 1.00 113.09 ? 307 PRO A CA    1 
ATOM   9017  C  C     . PRO C 2 307 ? 389.193 392.105 274.531 1.00 115.76 ? 307 PRO A C     1 
ATOM   9018  O  O     . PRO C 2 307 ? 390.176 392.394 273.836 1.00 116.79 ? 307 PRO A O     1 
ATOM   9019  C  CB    . PRO C 2 307 ? 388.331 389.780 274.083 1.00 110.07 ? 307 PRO A CB    1 
ATOM   9020  C  CG    . PRO C 2 307 ? 387.479 388.908 274.911 1.00 112.71 ? 307 PRO A CG    1 
ATOM   9021  C  CD    . PRO C 2 307 ? 387.045 389.764 276.045 1.00 112.88 ? 307 PRO A CD    1 
ATOM   9022  N  N     . ARG C 2 308 ? 388.250 392.996 274.845 1.00 117.17 ? 308 ARG A N     1 
ATOM   9023  C  CA    . ARG C 2 308 ? 388.376 394.397 274.470 1.00 113.32 ? 308 ARG A CA    1 
ATOM   9024  C  C     . ARG C 2 308 ? 389.581 395.066 275.121 1.00 114.02 ? 308 ARG A C     1 
ATOM   9025  O  O     . ARG C 2 308 ? 390.070 396.069 274.592 1.00 114.03 ? 308 ARG A O     1 
ATOM   9026  C  CB    . ARG C 2 308 ? 387.098 395.149 274.840 1.00 114.48 ? 308 ARG A CB    1 
ATOM   9027  C  CG    . ARG C 2 308 ? 385.872 394.702 274.052 1.00 116.62 ? 308 ARG A CG    1 
ATOM   9028  C  CD    . ARG C 2 308 ? 384.596 395.345 274.572 1.00 118.62 ? 308 ARG A CD    1 
ATOM   9029  N  NE    . ARG C 2 308 ? 384.227 394.847 275.893 1.00 125.46 ? 308 ARG A NE    1 
ATOM   9030  C  CZ    . ARG C 2 308 ? 383.141 395.201 276.571 1.00 123.67 ? 308 ARG A CZ    1 
ATOM   9031  N  NH1   . ARG C 2 308 ? 382.260 396.064 276.085 1.00 123.31 ? 308 ARG A NH1   1 
ATOM   9032  N  NH2   . ARG C 2 308 ? 382.929 394.673 277.773 1.00 119.13 ? 308 ARG A NH2   1 
ATOM   9033  N  N     . HIS C 2 309 ? 390.075 394.541 276.248 1.00 117.71 ? 309 HIS A N     1 
ATOM   9034  C  CA    . HIS C 2 309 ? 391.308 395.061 276.827 1.00 118.34 ? 309 HIS A CA    1 
ATOM   9035  C  C     . HIS C 2 309 ? 392.553 394.676 276.035 1.00 114.45 ? 309 HIS A C     1 
ATOM   9036  O  O     . HIS C 2 309 ? 393.630 395.200 276.338 1.00 116.74 ? 309 HIS A O     1 
ATOM   9037  C  CB    . HIS C 2 309 ? 391.472 394.575 278.270 1.00 122.16 ? 309 HIS A CB    1 
ATOM   9038  C  CG    . HIS C 2 309 ? 390.459 395.129 279.226 1.00 121.80 ? 309 HIS A CG    1 
ATOM   9039  N  ND1   . HIS C 2 309 ? 389.690 396.239 278.948 1.00 118.23 ? 309 HIS A ND1   1 
ATOM   9040  C  CD2   . HIS C 2 309 ? 390.108 394.734 280.472 1.00 120.31 ? 309 HIS A CD2   1 
ATOM   9041  C  CE1   . HIS C 2 309 ? 388.898 396.493 279.974 1.00 117.08 ? 309 HIS A CE1   1 
ATOM   9042  N  NE2   . HIS C 2 309 ? 389.133 395.594 280.913 1.00 121.03 ? 309 HIS A NE2   1 
ATOM   9043  N  N     . GLY C 2 310 ? 392.442 393.777 275.053 1.00 108.63 ? 310 GLY A N     1 
ATOM   9044  C  CA    . GLY C 2 310 ? 393.566 393.392 274.220 1.00 112.44 ? 310 GLY A CA    1 
ATOM   9045  C  C     . GLY C 2 310 ? 393.160 393.211 272.774 1.00 110.99 ? 310 GLY A C     1 
ATOM   9046  O  O     . GLY C 2 310 ? 392.108 393.705 272.357 1.00 112.61 ? 310 GLY A O     1 
ATOM   9047  N  N     . LYS C 2 311 ? 393.991 392.508 272.005 1.00 100.70 ? 311 LYS A N     1 
ATOM   9048  C  CA    . LYS C 2 311 ? 393.751 392.232 270.596 1.00 102.50 ? 311 LYS A CA    1 
ATOM   9049  C  C     . LYS C 2 311 ? 393.891 390.741 270.346 1.00 104.46 ? 311 LYS A C     1 
ATOM   9050  O  O     . LYS C 2 311 ? 394.801 390.096 270.873 1.00 104.40 ? 311 LYS A O     1 
ATOM   9051  C  CB    . LYS C 2 311 ? 394.729 392.990 269.699 1.00 100.21 ? 311 LYS A CB    1 
ATOM   9052  C  CG    . LYS C 2 311 ? 394.551 394.493 269.709 1.00 104.80 ? 311 LYS A CG    1 
ATOM   9053  C  CD    . LYS C 2 311 ? 395.486 395.155 268.713 1.00 105.93 ? 311 LYS A CD    1 
ATOM   9054  C  CE    . LYS C 2 311 ? 395.340 396.663 268.730 1.00 107.10 ? 311 LYS A CE    1 
ATOM   9055  N  NZ    . LYS C 2 311 ? 395.976 397.265 269.930 1.00 111.17 ? 311 LYS A NZ    1 
ATOM   9056  N  N     . TYR C 2 312 ? 392.986 390.197 269.540 1.00 101.12 ? 312 TYR A N     1 
ATOM   9057  C  CA    . TYR C 2 312 ? 393.099 388.807 269.137 1.00 95.96  ? 312 TYR A CA    1 
ATOM   9058  C  C     . TYR C 2 312 ? 394.303 388.623 268.225 1.00 97.96  ? 312 TYR A C     1 
ATOM   9059  O  O     . TYR C 2 312 ? 394.650 389.504 267.434 1.00 104.94 ? 312 TYR A O     1 
ATOM   9060  C  CB    . TYR C 2 312 ? 391.826 388.348 268.431 1.00 93.95  ? 312 TYR A CB    1 
ATOM   9061  C  CG    . TYR C 2 312 ? 390.645 388.206 269.356 1.00 93.86  ? 312 TYR A CG    1 
ATOM   9062  C  CD1   . TYR C 2 312 ? 390.542 387.119 270.210 1.00 96.19  ? 312 TYR A CD1   1 
ATOM   9063  C  CD2   . TYR C 2 312 ? 389.635 389.153 269.377 1.00 95.59  ? 312 TYR A CD2   1 
ATOM   9064  C  CE1   . TYR C 2 312 ? 389.468 386.980 271.058 1.00 99.11  ? 312 TYR A CE1   1 
ATOM   9065  C  CE2   . TYR C 2 312 ? 388.555 389.022 270.221 1.00 98.87  ? 312 TYR A CE2   1 
ATOM   9066  C  CZ    . TYR C 2 312 ? 388.476 387.933 271.059 1.00 101.44 ? 312 TYR A CZ    1 
ATOM   9067  O  OH    . TYR C 2 312 ? 387.400 387.800 271.904 1.00 103.99 ? 312 TYR A OH    1 
ATOM   9068  N  N     . MET C 2 313 ? 394.951 387.465 268.365 1.00 96.17  ? 313 MET A N     1 
ATOM   9069  C  CA    . MET C 2 313 ? 396.108 387.097 267.554 1.00 95.73  ? 313 MET A CA    1 
ATOM   9070  C  C     . MET C 2 313 ? 395.979 385.725 266.915 1.00 100.33 ? 313 MET A C     1 
ATOM   9071  O  O     . MET C 2 313 ? 396.711 385.450 265.957 1.00 102.62 ? 313 MET A O     1 
ATOM   9072  C  CB    . MET C 2 313 ? 397.417 387.143 268.374 1.00 91.62  ? 313 MET A CB    1 
ATOM   9073  C  CG    . MET C 2 313 ? 397.372 386.654 269.831 1.00 97.40  ? 313 MET A CG    1 
ATOM   9074  S  SD    . MET C 2 313 ? 398.739 387.192 270.881 1.00 114.54 ? 313 MET A SD    1 
ATOM   9075  C  CE    . MET C 2 313 ? 400.115 387.161 269.752 1.00 105.68 ? 313 MET A CE    1 
ATOM   9076  N  N     . ALA C 2 314 ? 395.087 384.859 267.397 1.00 103.27 ? 314 ALA A N     1 
ATOM   9077  C  CA    . ALA C 2 314 ? 394.765 383.636 266.659 1.00 97.16  ? 314 ALA A CA    1 
ATOM   9078  C  C     . ALA C 2 314 ? 393.466 383.060 267.192 1.00 99.93  ? 314 ALA A C     1 
ATOM   9079  O  O     . ALA C 2 314 ? 393.417 382.637 268.347 1.00 107.09 ? 314 ALA A O     1 
ATOM   9080  C  CB    . ALA C 2 314 ? 395.891 382.608 266.773 1.00 99.95  ? 314 ALA A CB    1 
ATOM   9081  N  N     . CYS C 2 315 ? 392.439 382.999 266.349 1.00 104.89 ? 315 CYS A N     1 
ATOM   9082  C  CA    . CYS C 2 315 ? 391.143 382.434 266.702 1.00 106.93 ? 315 CYS A CA    1 
ATOM   9083  C  C     . CYS C 2 315 ? 390.937 381.142 265.928 1.00 108.38 ? 315 CYS A C     1 
ATOM   9084  O  O     . CYS C 2 315 ? 391.361 381.031 264.776 1.00 113.65 ? 315 CYS A O     1 
ATOM   9085  C  CB    . CYS C 2 315 ? 390.015 383.416 266.400 1.00 108.23 ? 315 CYS A CB    1 
ATOM   9086  S  SG    . CYS C 2 315 ? 389.814 384.678 267.670 1.00 123.77 ? 315 CYS A SG    1 
ATOM   9087  N  N     . CYS C 2 316 ? 390.310 380.161 266.576 1.00 100.90 ? 316 CYS A N     1 
ATOM   9088  C  CA    . CYS C 2 316 ? 390.043 378.855 265.986 1.00 104.14 ? 316 CYS A CA    1 
ATOM   9089  C  C     . CYS C 2 316 ? 388.634 378.436 266.367 1.00 109.80 ? 316 CYS A C     1 
ATOM   9090  O  O     . CYS C 2 316 ? 388.336 378.264 267.552 1.00 114.49 ? 316 CYS A O     1 
ATOM   9091  C  CB    . CYS C 2 316 ? 391.060 377.815 266.461 1.00 103.51 ? 316 CYS A CB    1 
ATOM   9092  S  SG    . CYS C 2 316 ? 390.719 376.132 265.903 1.00 109.72 ? 316 CYS A SG    1 
ATOM   9093  N  N     . LEU C 2 317 ? 387.782 378.262 265.364 1.00 101.58 ? 317 LEU A N     1 
ATOM   9094  C  CA    . LEU C 2 317 ? 386.378 377.918 265.535 1.00 93.57  ? 317 LEU A CA    1 
ATOM   9095  C  C     . LEU C 2 317 ? 386.162 376.488 265.071 1.00 96.44  ? 317 LEU A C     1 
ATOM   9096  O  O     . LEU C 2 317 ? 386.625 376.107 263.989 1.00 103.00 ? 317 LEU A O     1 
ATOM   9097  C  CB    . LEU C 2 317 ? 385.497 378.879 264.743 1.00 95.30  ? 317 LEU A CB    1 
ATOM   9098  C  CG    . LEU C 2 317 ? 385.645 380.344 265.172 1.00 97.05  ? 317 LEU A CG    1 
ATOM   9099  C  CD1   . LEU C 2 317 ? 386.092 381.233 264.022 1.00 104.62 ? 317 LEU A CD1   1 
ATOM   9100  C  CD2   . LEU C 2 317 ? 384.328 380.846 265.747 1.00 99.70  ? 317 LEU A CD2   1 
ATOM   9101  N  N     . LEU C 2 318 ? 385.470 375.706 265.895 1.00 92.48  ? 318 LEU A N     1 
ATOM   9102  C  CA    . LEU C 2 318 ? 385.241 374.281 265.678 1.00 98.01  ? 318 LEU A CA    1 
ATOM   9103  C  C     . LEU C 2 318 ? 383.736 374.067 265.690 1.00 102.09 ? 318 LEU A C     1 
ATOM   9104  O  O     . LEU C 2 318 ? 383.137 373.916 266.756 1.00 110.54 ? 318 LEU A O     1 
ATOM   9105  C  CB    . LEU C 2 318 ? 385.921 373.478 266.747 1.00 94.41  ? 318 LEU A CB    1 
ATOM   9106  C  CG    . LEU C 2 318 ? 387.416 373.728 266.949 1.00 91.98  ? 318 LEU A CG    1 
ATOM   9107  C  CD1   . LEU C 2 318 ? 387.917 372.942 268.135 1.00 95.36  ? 318 LEU A CD1   1 
ATOM   9108  C  CD2   . LEU C 2 318 ? 388.201 373.365 265.706 1.00 96.15  ? 318 LEU A CD2   1 
ATOM   9109  N  N     . TYR C 2 319 ? 383.131 374.107 264.507 1.00 93.32  ? 319 TYR A N     1 
ATOM   9110  C  CA    . TYR C 2 319 ? 381.704 373.873 264.369 1.00 87.10  ? 319 TYR A CA    1 
ATOM   9111  C  C     . TYR C 2 319 ? 381.409 372.382 264.276 1.00 89.94  ? 319 TYR A C     1 
ATOM   9112  O  O     . TYR C 2 319 ? 382.144 371.618 263.637 1.00 95.82  ? 319 TYR A O     1 
ATOM   9113  C  CB    . TYR C 2 319 ? 381.170 374.585 263.129 1.00 92.14  ? 319 TYR A CB    1 
ATOM   9114  C  CG    . TYR C 2 319 ? 381.237 376.091 263.208 1.00 89.13  ? 319 TYR A CG    1 
ATOM   9115  C  CD1   . TYR C 2 319 ? 382.380 376.777 262.826 1.00 90.00  ? 319 TYR A CD1   1 
ATOM   9116  C  CD2   . TYR C 2 319 ? 380.155 376.828 263.662 1.00 91.60  ? 319 TYR A CD2   1 
ATOM   9117  C  CE1   . TYR C 2 319 ? 382.443 378.152 262.897 1.00 93.22  ? 319 TYR A CE1   1 
ATOM   9118  C  CE2   . TYR C 2 319 ? 380.209 378.202 263.738 1.00 91.91  ? 319 TYR A CE2   1 
ATOM   9119  C  CZ    . TYR C 2 319 ? 381.354 378.859 263.354 1.00 94.96  ? 319 TYR A CZ    1 
ATOM   9120  O  OH    . TYR C 2 319 ? 381.410 380.230 263.427 1.00 100.86 ? 319 TYR A OH    1 
ATOM   9121  N  N     . ARG C 2 320 ? 380.312 371.976 264.908 1.00 103.20 ? 320 ARG A N     1 
ATOM   9122  C  CA    . ARG C 2 320 ? 379.878 370.591 264.889 1.00 103.31 ? 320 ARG A CA    1 
ATOM   9123  C  C     . ARG C 2 320 ? 378.362 370.547 264.777 1.00 109.15 ? 320 ARG A C     1 
ATOM   9124  O  O     . ARG C 2 320 ? 377.652 371.242 265.514 1.00 110.15 ? 320 ARG A O     1 
ATOM   9125  C  CB    . ARG C 2 320 ? 380.378 369.843 266.129 1.00 101.01 ? 320 ARG A CB    1 
ATOM   9126  C  CG    . ARG C 2 320 ? 379.718 370.200 267.440 1.00 102.73 ? 320 ARG A CG    1 
ATOM   9127  C  CD    . ARG C 2 320 ? 380.498 369.624 268.612 1.00 100.62 ? 320 ARG A CD    1 
ATOM   9128  N  NE    . ARG C 2 320 ? 380.603 368.169 268.537 1.00 102.31 ? 320 ARG A NE    1 
ATOM   9129  C  CZ    . ARG C 2 320 ? 380.903 367.363 269.549 1.00 108.46 ? 320 ARG A CZ    1 
ATOM   9130  N  NH1   . ARG C 2 320 ? 381.143 367.824 270.768 1.00 109.44 ? 320 ARG A NH1   1 
ATOM   9131  N  NH2   . ARG C 2 320 ? 380.969 366.052 269.331 1.00 107.78 ? 320 ARG A NH2   1 
ATOM   9132  N  N     . GLY C 2 321 ? 377.883 369.738 263.826 1.00 111.61 ? 321 GLY A N     1 
ATOM   9133  C  CA    . GLY C 2 321 ? 376.467 369.499 263.627 1.00 112.91 ? 321 GLY A CA    1 
ATOM   9134  C  C     . GLY C 2 321 ? 375.999 369.978 262.263 1.00 112.65 ? 321 GLY A C     1 
ATOM   9135  O  O     . GLY C 2 321 ? 376.754 369.950 261.283 1.00 111.42 ? 321 GLY A O     1 
ATOM   9136  N  N     . ASP C 2 322 ? 374.742 370.417 262.213 1.00 123.18 ? 322 ASP A N     1 
ATOM   9137  C  CA    . ASP C 2 322 ? 374.105 370.824 260.960 1.00 125.72 ? 322 ASP A CA    1 
ATOM   9138  C  C     . ASP C 2 322 ? 374.621 372.238 260.707 1.00 125.88 ? 322 ASP A C     1 
ATOM   9139  O  O     . ASP C 2 322 ? 374.051 373.232 261.158 1.00 127.42 ? 322 ASP A O     1 
ATOM   9140  C  CB    . ASP C 2 322 ? 372.579 370.712 261.075 1.00 129.37 ? 322 ASP A CB    1 
ATOM   9141  C  CG    . ASP C 2 322 ? 371.799 371.671 260.158 1.00 130.57 ? 322 ASP A CG    1 
ATOM   9142  O  OD1   . ASP C 2 322 ? 372.248 371.984 259.034 1.00 129.82 ? 322 ASP A OD1   1 
ATOM   9143  O  OD2   . ASP C 2 322 ? 370.711 372.116 260.581 1.00 126.24 ? 322 ASP A OD2   1 
ATOM   9144  N  N     . VAL C 2 323 ? 375.754 372.316 260.009 1.00 105.99 ? 323 VAL A N     1 
ATOM   9145  C  CA    . VAL C 2 323 ? 376.490 373.557 259.801 1.00 103.15 ? 323 VAL A CA    1 
ATOM   9146  C  C     . VAL C 2 323 ? 376.945 373.613 258.352 1.00 103.05 ? 323 VAL A C     1 
ATOM   9147  O  O     . VAL C 2 323 ? 377.445 372.619 257.814 1.00 106.73 ? 323 VAL A O     1 
ATOM   9148  C  CB    . VAL C 2 323 ? 377.694 373.663 260.759 1.00 96.69  ? 323 VAL A CB    1 
ATOM   9149  C  CG1   . VAL C 2 323 ? 378.511 374.897 260.438 1.00 99.68  ? 323 VAL A CG1   1 
ATOM   9150  C  CG2   . VAL C 2 323 ? 377.216 373.690 262.211 1.00 103.80 ? 323 VAL A CG2   1 
ATOM   9151  N  N     . VAL C 2 324 ? 376.789 374.784 257.735 1.00 102.76 ? 324 VAL A N     1 
ATOM   9152  C  CA    . VAL C 2 324 ? 377.062 374.993 256.314 1.00 102.33 ? 324 VAL A CA    1 
ATOM   9153  C  C     . VAL C 2 324 ? 378.334 375.833 256.176 1.00 107.47 ? 324 VAL A C     1 
ATOM   9154  O  O     . VAL C 2 324 ? 378.489 376.824 256.917 1.00 114.81 ? 324 VAL A O     1 
ATOM   9155  C  CB    . VAL C 2 324 ? 375.869 375.664 255.613 1.00 106.41 ? 324 VAL A CB    1 
ATOM   9156  C  CG1   . VAL C 2 324 ? 376.134 375.797 254.110 1.00 107.11 ? 324 VAL A CG1   1 
ATOM   9157  C  CG2   . VAL C 2 324 ? 374.585 374.868 255.873 1.00 109.17 ? 324 VAL A CG2   1 
ATOM   9158  N  N     . PRO C 2 325 ? 379.270 375.497 255.267 1.00 105.36 ? 325 PRO A N     1 
ATOM   9159  C  CA    . PRO C 2 325 ? 380.471 376.339 255.139 1.00 105.52 ? 325 PRO A CA    1 
ATOM   9160  C  C     . PRO C 2 325 ? 380.180 377.762 254.704 1.00 105.26 ? 325 PRO A C     1 
ATOM   9161  O  O     . PRO C 2 325 ? 380.890 378.672 255.135 1.00 109.98 ? 325 PRO A O     1 
ATOM   9162  C  CB    . PRO C 2 325 ? 381.320 375.600 254.094 1.00 106.73 ? 325 PRO A CB    1 
ATOM   9163  C  CG    . PRO C 2 325 ? 380.786 374.238 254.049 1.00 106.40 ? 325 PRO A CG    1 
ATOM   9164  C  CD    . PRO C 2 325 ? 379.331 374.380 254.304 1.00 108.10 ? 325 PRO A CD    1 
ATOM   9165  N  N     . LYS C 2 326 ? 379.163 377.992 253.873 1.00 99.68  ? 326 LYS A N     1 
ATOM   9166  C  CA    . LYS C 2 326 ? 378.799 379.365 253.539 1.00 102.24 ? 326 LYS A CA    1 
ATOM   9167  C  C     . LYS C 2 326 ? 378.344 380.122 254.780 1.00 106.40 ? 326 LYS A C     1 
ATOM   9168  O  O     . LYS C 2 326 ? 378.674 381.303 254.950 1.00 109.14 ? 326 LYS A O     1 
ATOM   9169  C  CB    . LYS C 2 326 ? 377.709 379.377 252.466 1.00 103.92 ? 326 LYS A CB    1 
ATOM   9170  C  CG    . LYS C 2 326 ? 377.358 380.767 251.933 1.00 105.53 ? 326 LYS A CG    1 
ATOM   9171  C  CD    . LYS C 2 326 ? 376.117 380.743 251.073 1.00 107.64 ? 326 LYS A CD    1 
ATOM   9172  C  CE    . LYS C 2 326 ? 375.761 382.145 250.622 1.00 107.24 ? 326 LYS A CE    1 
ATOM   9173  N  NZ    . LYS C 2 326 ? 376.793 382.729 249.724 1.00 111.30 ? 326 LYS A NZ    1 
ATOM   9174  N  N     . ASP C 2 327 ? 377.582 379.461 255.652 1.00 115.59 ? 327 ASP A N     1 
ATOM   9175  C  CA    . ASP C 2 327 ? 377.099 380.118 256.859 1.00 115.78 ? 327 ASP A CA    1 
ATOM   9176  C  C     . ASP C 2 327 ? 378.256 380.502 257.772 1.00 112.76 ? 327 ASP A C     1 
ATOM   9177  O  O     . ASP C 2 327 ? 378.331 381.650 258.242 1.00 112.71 ? 327 ASP A O     1 
ATOM   9178  C  CB    . ASP C 2 327 ? 376.112 379.208 257.588 1.00 119.51 ? 327 ASP A CB    1 
ATOM   9179  C  CG    . ASP C 2 327 ? 374.761 379.138 256.899 1.00 123.88 ? 327 ASP A CG    1 
ATOM   9180  O  OD1   . ASP C 2 327 ? 374.620 379.689 255.787 1.00 123.97 ? 327 ASP A OD1   1 
ATOM   9181  O  OD2   . ASP C 2 327 ? 373.835 378.528 257.473 1.00 123.07 ? 327 ASP A OD2   1 
ATOM   9182  N  N     . VAL C 2 328 ? 379.190 379.568 258.009 1.00 108.23 ? 328 VAL A N     1 
ATOM   9183  C  CA    . VAL C 2 328 ? 380.313 379.926 258.878 1.00 103.49 ? 328 VAL A CA    1 
ATOM   9184  C  C     . VAL C 2 328 ? 381.176 380.984 258.204 1.00 102.88 ? 328 VAL A C     1 
ATOM   9185  O  O     . VAL C 2 328 ? 381.664 381.893 258.874 1.00 113.94 ? 328 VAL A O     1 
ATOM   9186  C  CB    . VAL C 2 328 ? 381.160 378.707 259.324 1.00 104.48 ? 328 VAL A CB    1 
ATOM   9187  C  CG1   . VAL C 2 328 ? 380.289 377.551 259.776 1.00 112.13 ? 328 VAL A CG1   1 
ATOM   9188  C  CG2   . VAL C 2 328 ? 382.158 378.248 258.266 1.00 106.44 ? 328 VAL A CG2   1 
ATOM   9189  N  N     . ASN C 2 329 ? 381.332 380.921 256.879 1.00 110.55 ? 329 ASN A N     1 
ATOM   9190  C  CA    . ASN C 2 329 ? 382.161 381.890 256.170 1.00 110.74 ? 329 ASN A CA    1 
ATOM   9191  C  C     . ASN C 2 329 ? 381.601 383.300 256.296 1.00 110.20 ? 329 ASN A C     1 
ATOM   9192  O  O     . ASN C 2 329 ? 382.341 384.253 256.576 1.00 112.58 ? 329 ASN A O     1 
ATOM   9193  C  CB    . ASN C 2 329 ? 382.265 381.483 254.703 1.00 114.29 ? 329 ASN A CB    1 
ATOM   9194  C  CG    . ASN C 2 329 ? 383.376 382.184 253.988 1.00 119.26 ? 329 ASN A CG    1 
ATOM   9195  O  OD1   . ASN C 2 329 ? 384.547 381.917 254.245 1.00 118.79 ? 329 ASN A OD1   1 
ATOM   9196  N  ND2   . ASN C 2 329 ? 383.022 383.083 253.075 1.00 117.99 ? 329 ASN A ND2   1 
ATOM   9197  N  N     . ALA C 2 330 ? 380.288 383.447 256.108 1.00 107.68 ? 330 ALA A N     1 
ATOM   9198  C  CA    . ALA C 2 330 ? 379.666 384.756 256.268 1.00 108.41 ? 330 ALA A CA    1 
ATOM   9199  C  C     . ALA C 2 330 ? 379.786 385.245 257.704 1.00 113.94 ? 330 ALA A C     1 
ATOM   9200  O  O     . ALA C 2 330 ? 380.034 386.435 257.942 1.00 119.44 ? 330 ALA A O     1 
ATOM   9201  C  CB    . ALA C 2 330 ? 378.200 384.699 255.839 1.00 109.62 ? 330 ALA A CB    1 
ATOM   9202  N  N     . ALA C 2 331 ? 379.634 384.338 258.677 1.00 106.21 ? 331 ALA A N     1 
ATOM   9203  C  CA    . ALA C 2 331 ? 379.759 384.744 260.074 1.00 99.88  ? 331 ALA A CA    1 
ATOM   9204  C  C     . ALA C 2 331 ? 381.170 385.235 260.393 1.00 101.95 ? 331 ALA A C     1 
ATOM   9205  O  O     . ALA C 2 331 ? 381.340 386.262 261.065 1.00 107.28 ? 331 ALA A O     1 
ATOM   9206  C  CB    . ALA C 2 331 ? 379.375 383.584 260.990 1.00 105.54 ? 331 ALA A CB    1 
ATOM   9207  N  N     . ILE C 2 332 ? 382.194 384.525 259.912 1.00 107.31 ? 332 ILE A N     1 
ATOM   9208  C  CA    . ILE C 2 332 ? 383.565 384.938 260.210 1.00 103.92 ? 332 ILE A CA    1 
ATOM   9209  C  C     . ILE C 2 332 ? 383.892 386.241 259.494 1.00 111.28 ? 332 ILE A C     1 
ATOM   9210  O  O     . ILE C 2 332 ? 384.627 387.080 260.028 1.00 118.94 ? 332 ILE A O     1 
ATOM   9211  C  CB    . ILE C 2 332 ? 384.599 383.835 259.872 1.00 105.96 ? 332 ILE A CB    1 
ATOM   9212  C  CG1   . ILE C 2 332 ? 384.288 382.463 260.534 1.00 107.15 ? 332 ILE A CG1   1 
ATOM   9213  C  CG2   . ILE C 2 332 ? 386.032 384.323 260.182 1.00 111.86 ? 332 ILE A CG2   1 
ATOM   9214  C  CD1   . ILE C 2 332 ? 383.558 382.470 261.874 1.00 109.69 ? 332 ILE A CD1   1 
ATOM   9215  N  N     . ALA C 2 333 ? 383.381 386.428 258.274 1.00 108.21 ? 333 ALA A N     1 
ATOM   9216  C  CA    . ALA C 2 333 ? 383.603 387.695 257.581 1.00 107.00 ? 333 ALA A CA    1 
ATOM   9217  C  C     . ALA C 2 333 ? 382.965 388.854 258.340 1.00 108.41 ? 333 ALA A C     1 
ATOM   9218  O  O     . ALA C 2 333 ? 383.561 389.932 258.463 1.00 114.31 ? 333 ALA A O     1 
ATOM   9219  C  CB    . ALA C 2 333 ? 383.055 387.616 256.158 1.00 102.71 ? 333 ALA A CB    1 
ATOM   9220  N  N     . THR C 2 334 ? 381.760 388.639 258.871 1.00 109.27 ? 334 THR A N     1 
ATOM   9221  C  CA    . THR C 2 334 ? 381.100 389.659 259.684 1.00 110.30 ? 334 THR A CA    1 
ATOM   9222  C  C     . THR C 2 334 ? 381.925 389.993 260.925 1.00 110.52 ? 334 THR A C     1 
ATOM   9223  O  O     . THR C 2 334 ? 382.143 391.171 261.251 1.00 113.87 ? 334 THR A O     1 
ATOM   9224  C  CB    . THR C 2 334 ? 379.705 389.160 260.072 1.00 109.61 ? 334 THR A CB    1 
ATOM   9225  O  OG1   . THR C 2 334 ? 379.045 388.635 258.912 1.00 112.34 ? 334 THR A OG1   1 
ATOM   9226  C  CG2   . THR C 2 334 ? 378.858 390.269 260.655 1.00 107.76 ? 334 THR A CG2   1 
ATOM   9227  N  N     . ILE C 2 335 ? 382.412 388.959 261.617 1.00 110.41 ? 335 ILE A N     1 
ATOM   9228  C  CA    . ILE C 2 335 ? 383.170 389.178 262.846 1.00 106.52 ? 335 ILE A CA    1 
ATOM   9229  C  C     . ILE C 2 335 ? 384.486 389.884 262.542 1.00 106.62 ? 335 ILE A C     1 
ATOM   9230  O  O     . ILE C 2 335 ? 384.958 390.709 263.332 1.00 106.55 ? 335 ILE A O     1 
ATOM   9231  C  CB    . ILE C 2 335 ? 383.396 387.843 263.583 1.00 111.30 ? 335 ILE A CB    1 
ATOM   9232  C  CG1   . ILE C 2 335 ? 382.071 387.265 264.106 1.00 111.31 ? 335 ILE A CG1   1 
ATOM   9233  C  CG2   . ILE C 2 335 ? 384.390 388.010 264.731 1.00 109.18 ? 335 ILE A CG2   1 
ATOM   9234  C  CD1   . ILE C 2 335 ? 381.496 387.944 265.348 1.00 107.22 ? 335 ILE A CD1   1 
ATOM   9235  N  N     . LYS C 2 336 ? 385.103 389.566 261.402 1.00 110.18 ? 336 LYS A N     1 
ATOM   9236  C  CA    . LYS C 2 336 ? 386.293 390.295 260.981 1.00 108.94 ? 336 LYS A CA    1 
ATOM   9237  C  C     . LYS C 2 336 ? 385.960 391.755 260.705 1.00 112.98 ? 336 LYS A C     1 
ATOM   9238  O  O     . LYS C 2 336 ? 386.760 392.642 261.026 1.00 116.91 ? 336 LYS A O     1 
ATOM   9239  C  CB    . LYS C 2 336 ? 386.914 389.605 259.750 1.00 108.57 ? 336 LYS A CB    1 
ATOM   9240  C  CG    . LYS C 2 336 ? 387.885 390.438 258.852 1.00 115.13 ? 336 LYS A CG    1 
ATOM   9241  C  CD    . LYS C 2 336 ? 388.339 389.696 257.579 1.00 113.33 ? 336 LYS A CD    1 
ATOM   9242  C  CE    . LYS C 2 336 ? 388.906 388.300 257.817 1.00 112.37 ? 336 LYS A CE    1 
ATOM   9243  N  NZ    . LYS C 2 336 ? 389.955 388.283 258.874 1.00 113.19 ? 336 LYS A NZ    1 
ATOM   9244  N  N     . THR C 2 337 ? 384.793 392.025 260.112 1.00 119.45 ? 337 THR A N     1 
ATOM   9245  C  CA    . THR C 2 337 ? 384.479 393.397 259.730 1.00 118.63 ? 337 THR A CA    1 
ATOM   9246  C  C     . THR C 2 337 ? 384.201 394.261 260.956 1.00 120.47 ? 337 THR A C     1 
ATOM   9247  O  O     . THR C 2 337 ? 384.515 395.458 260.942 1.00 122.04 ? 337 THR A O     1 
ATOM   9248  C  CB    . THR C 2 337 ? 383.286 393.419 258.765 1.00 120.67 ? 337 THR A CB    1 
ATOM   9249  O  OG1   . THR C 2 337 ? 383.745 393.115 257.444 1.00 122.14 ? 337 THR A OG1   1 
ATOM   9250  C  CG2   . THR C 2 337 ? 382.615 394.803 258.682 1.00 122.92 ? 337 THR A CG2   1 
ATOM   9251  N  N     . LYS C 2 338 ? 383.616 393.689 262.012 1.00 129.12 ? 338 LYS A N     1 
ATOM   9252  C  CA    . LYS C 2 338 ? 383.343 394.470 263.218 1.00 130.14 ? 338 LYS A CA    1 
ATOM   9253  C  C     . LYS C 2 338 ? 384.632 394.982 263.858 1.00 131.37 ? 338 LYS A C     1 
ATOM   9254  O  O     . LYS C 2 338 ? 385.656 394.293 263.870 1.00 128.18 ? 338 LYS A O     1 
ATOM   9255  C  CB    . LYS C 2 338 ? 382.549 393.643 264.242 1.00 128.19 ? 338 LYS A CB    1 
ATOM   9256  C  CG    . LYS C 2 338 ? 381.149 393.056 263.883 1.00 130.97 ? 338 LYS A CG    1 
ATOM   9257  C  CD    . LYS C 2 338 ? 380.233 393.891 262.945 1.00 132.44 ? 338 LYS A CD    1 
ATOM   9258  C  CE    . LYS C 2 338 ? 380.307 393.622 261.450 1.00 131.14 ? 338 LYS A CE    1 
ATOM   9259  N  NZ    . LYS C 2 338 ? 379.625 394.681 260.664 1.00 128.89 ? 338 LYS A NZ    1 
ATOM   9260  N  N     . ARG C 2 339 ? 384.566 396.209 264.392 1.00 141.67 ? 339 ARG A N     1 
ATOM   9261  C  CA    . ARG C 2 339 ? 385.723 396.911 264.943 1.00 141.73 ? 339 ARG A CA    1 
ATOM   9262  C  C     . ARG C 2 339 ? 385.812 396.870 266.461 1.00 136.76 ? 339 ARG A C     1 
ATOM   9263  O  O     . ARG C 2 339 ? 386.891 397.136 267.002 1.00 137.88 ? 339 ARG A O     1 
ATOM   9264  C  CB    . ARG C 2 339 ? 385.720 398.380 264.497 1.00 144.47 ? 339 ARG A CB    1 
ATOM   9265  C  CG    . ARG C 2 339 ? 385.912 398.601 262.991 1.00 143.88 ? 339 ARG A CG    1 
ATOM   9266  C  CD    . ARG C 2 339 ? 387.320 398.226 262.518 1.00 144.81 ? 339 ARG A CD    1 
ATOM   9267  N  NE    . ARG C 2 339 ? 387.421 396.810 262.167 1.00 146.90 ? 339 ARG A NE    1 
ATOM   9268  C  CZ    . ARG C 2 339 ? 388.515 396.059 262.252 1.00 144.75 ? 339 ARG A CZ    1 
ATOM   9269  N  NH1   . ARG C 2 339 ? 389.688 396.558 262.620 1.00 142.92 ? 339 ARG A NH1   1 
ATOM   9270  N  NH2   . ARG C 2 339 ? 388.433 394.765 261.956 1.00 140.80 ? 339 ARG A NH2   1 
ATOM   9271  N  N     . SER C 2 340 ? 384.719 396.567 267.163 1.00 117.83 ? 340 SER A N     1 
ATOM   9272  C  CA    . SER C 2 340 ? 384.826 396.317 268.596 1.00 118.28 ? 340 SER A CA    1 
ATOM   9273  C  C     . SER C 2 340 ? 385.728 395.120 268.857 1.00 117.68 ? 340 SER A C     1 
ATOM   9274  O  O     . SER C 2 340 ? 386.523 395.121 269.804 1.00 113.79 ? 340 SER A O     1 
ATOM   9275  C  CB    . SER C 2 340 ? 383.441 396.090 269.198 1.00 118.73 ? 340 SER A CB    1 
ATOM   9276  O  OG    . SER C 2 340 ? 382.565 397.157 268.878 1.00 121.25 ? 340 SER A OG    1 
ATOM   9277  N  N     . ILE C 2 341 ? 385.617 394.095 268.020 1.00 116.80 ? 341 ILE A N     1 
ATOM   9278  C  CA    . ILE C 2 341 ? 386.541 392.968 268.015 1.00 113.90 ? 341 ILE A CA    1 
ATOM   9279  C  C     . ILE C 2 341 ? 387.729 393.362 267.146 1.00 112.28 ? 341 ILE A C     1 
ATOM   9280  O  O     . ILE C 2 341 ? 387.573 393.586 265.941 1.00 109.79 ? 341 ILE A O     1 
ATOM   9281  C  CB    . ILE C 2 341 ? 385.858 391.696 267.488 1.00 113.07 ? 341 ILE A CB    1 
ATOM   9282  C  CG1   . ILE C 2 341 ? 384.784 391.206 268.469 1.00 112.77 ? 341 ILE A CG1   1 
ATOM   9283  C  CG2   . ILE C 2 341 ? 386.878 390.593 267.234 1.00 113.53 ? 341 ILE A CG2   1 
ATOM   9284  C  CD1   . ILE C 2 341 ? 383.631 390.498 267.798 1.00 113.78 ? 341 ILE A CD1   1 
ATOM   9285  N  N     . GLN C 2 342 ? 388.913 393.440 267.758 1.00 111.79 ? 342 GLN A N     1 
ATOM   9286  C  CA    . GLN C 2 342 ? 390.131 393.900 267.104 1.00 110.32 ? 342 GLN A CA    1 
ATOM   9287  C  C     . GLN C 2 342 ? 391.144 392.769 267.015 1.00 106.35 ? 342 GLN A C     1 
ATOM   9288  O  O     . GLN C 2 342 ? 391.206 391.897 267.886 1.00 110.90 ? 342 GLN A O     1 
ATOM   9289  C  CB    . GLN C 2 342 ? 390.753 395.081 267.853 1.00 107.61 ? 342 GLN A CB    1 
ATOM   9290  C  CG    . GLN C 2 342 ? 389.876 396.322 267.869 1.00 115.35 ? 342 GLN A CG    1 
ATOM   9291  C  CD    . GLN C 2 342 ? 390.653 397.594 268.155 1.00 119.41 ? 342 GLN A CD    1 
ATOM   9292  O  OE1   . GLN C 2 342 ? 391.829 397.554 268.516 1.00 115.82 ? 342 GLN A OE1   1 
ATOM   9293  N  NE2   . GLN C 2 342 ? 389.994 398.734 267.986 1.00 122.50 ? 342 GLN A NE2   1 
ATOM   9294  N  N     . PHE C 2 343 ? 391.935 392.804 265.943 1.00 98.22  ? 343 PHE A N     1 
ATOM   9295  C  CA    . PHE C 2 343 ? 392.973 391.823 265.668 1.00 104.09 ? 343 PHE A CA    1 
ATOM   9296  C  C     . PHE C 2 343 ? 394.286 392.542 265.401 1.00 107.69 ? 343 PHE A C     1 
ATOM   9297  O  O     . PHE C 2 343 ? 394.311 393.711 265.011 1.00 110.93 ? 343 PHE A O     1 
ATOM   9298  C  CB    . PHE C 2 343 ? 392.613 390.944 264.464 1.00 106.65 ? 343 PHE A CB    1 
ATOM   9299  C  CG    . PHE C 2 343 ? 391.690 389.812 264.796 1.00 104.26 ? 343 PHE A CG    1 
ATOM   9300  C  CD1   . PHE C 2 343 ? 390.365 390.049 265.115 1.00 100.17 ? 343 PHE A CD1   1 
ATOM   9301  C  CD2   . PHE C 2 343 ? 392.149 388.507 264.790 1.00 108.01 ? 343 PHE A CD2   1 
ATOM   9302  C  CE1   . PHE C 2 343 ? 389.518 389.006 265.419 1.00 103.95 ? 343 PHE A CE1   1 
ATOM   9303  C  CE2   . PHE C 2 343 ? 391.305 387.462 265.095 1.00 112.49 ? 343 PHE A CE2   1 
ATOM   9304  C  CZ    . PHE C 2 343 ? 389.988 387.713 265.412 1.00 111.52 ? 343 PHE A CZ    1 
ATOM   9305  N  N     . VAL C 2 344 ? 395.386 391.825 265.629 1.00 104.45 ? 344 VAL A N     1 
ATOM   9306  C  CA    . VAL C 2 344 ? 396.703 392.370 265.329 1.00 100.24 ? 344 VAL A CA    1 
ATOM   9307  C  C     . VAL C 2 344 ? 396.842 392.549 263.824 1.00 104.61 ? 344 VAL A C     1 
ATOM   9308  O  O     . VAL C 2 344 ? 396.430 391.689 263.035 1.00 102.92 ? 344 VAL A O     1 
ATOM   9309  C  CB    . VAL C 2 344 ? 397.818 391.466 265.890 1.00 98.51  ? 344 VAL A CB    1 
ATOM   9310  C  CG1   . VAL C 2 344 ? 397.697 391.346 267.401 1.00 98.64  ? 344 VAL A CG1   1 
ATOM   9311  C  CG2   . VAL C 2 344 ? 397.833 390.084 265.223 1.00 106.21 ? 344 VAL A CG2   1 
ATOM   9312  N  N     . ASP C 2 345 ? 397.408 393.689 263.420 1.00 116.29 ? 345 ASP A N     1 
ATOM   9313  C  CA    . ASP C 2 345 ? 397.581 393.968 261.994 1.00 117.39 ? 345 ASP A CA    1 
ATOM   9314  C  C     . ASP C 2 345 ? 398.516 392.967 261.325 1.00 119.93 ? 345 ASP A C     1 
ATOM   9315  O  O     . ASP C 2 345 ? 398.336 392.644 260.146 1.00 121.66 ? 345 ASP A O     1 
ATOM   9316  C  CB    . ASP C 2 345 ? 398.095 395.399 261.775 1.00 116.22 ? 345 ASP A CB    1 
ATOM   9317  C  CG    . ASP C 2 345 ? 399.340 395.735 262.598 1.00 120.73 ? 345 ASP A CG    1 
ATOM   9318  O  OD1   . ASP C 2 345 ? 400.136 394.830 262.929 1.00 120.41 ? 345 ASP A OD1   1 
ATOM   9319  O  OD2   . ASP C 2 345 ? 399.520 396.928 262.916 1.00 122.99 ? 345 ASP A OD2   1 
ATOM   9320  N  N     . TRP C 2 346 ? 399.509 392.464 262.055 1.00 110.54 ? 346 TRP A N     1 
ATOM   9321  C  CA    . TRP C 2 346 ? 400.486 391.524 261.505 1.00 111.70 ? 346 TRP A CA    1 
ATOM   9322  C  C     . TRP C 2 346 ? 399.954 390.095 261.360 1.00 110.30 ? 346 TRP A C     1 
ATOM   9323  O  O     . TRP C 2 346 ? 400.734 389.211 260.992 1.00 112.65 ? 346 TRP A O     1 
ATOM   9324  C  CB    . TRP C 2 346 ? 401.766 391.508 262.358 1.00 109.45 ? 346 TRP A CB    1 
ATOM   9325  C  CG    . TRP C 2 346 ? 401.577 391.197 263.819 1.00 102.94 ? 346 TRP A CG    1 
ATOM   9326  C  CD1   . TRP C 2 346 ? 401.466 392.103 264.831 1.00 104.81 ? 346 TRP A CD1   1 
ATOM   9327  C  CD2   . TRP C 2 346 ? 401.479 389.903 264.427 1.00 98.24  ? 346 TRP A CD2   1 
ATOM   9328  N  NE1   . TRP C 2 346 ? 401.306 391.458 266.029 1.00 106.06 ? 346 TRP A NE1   1 
ATOM   9329  C  CE2   . TRP C 2 346 ? 401.309 390.106 265.810 1.00 102.12 ? 346 TRP A CE2   1 
ATOM   9330  C  CE3   . TRP C 2 346 ? 401.518 388.593 263.937 1.00 101.07 ? 346 TRP A CE3   1 
ATOM   9331  C  CZ2   . TRP C 2 346 ? 401.179 389.052 266.708 1.00 103.30 ? 346 TRP A CZ2   1 
ATOM   9332  C  CZ3   . TRP C 2 346 ? 401.387 387.548 264.832 1.00 107.81 ? 346 TRP A CZ3   1 
ATOM   9333  C  CH2   . TRP C 2 346 ? 401.220 387.783 266.203 1.00 104.72 ? 346 TRP A CH2   1 
ATOM   9334  N  N     . CYS C 2 347 ? 398.667 389.847 261.620 1.00 111.65 ? 347 CYS A N     1 
ATOM   9335  C  CA    . CYS C 2 347 ? 398.024 388.552 261.384 1.00 108.44 ? 347 CYS A CA    1 
ATOM   9336  C  C     . CYS C 2 347 ? 396.787 388.820 260.533 1.00 107.17 ? 347 CYS A C     1 
ATOM   9337  O  O     . CYS C 2 347 ? 395.670 388.899 261.062 1.00 110.15 ? 347 CYS A O     1 
ATOM   9338  C  CB    . CYS C 2 347 ? 397.665 387.861 262.700 1.00 110.36 ? 347 CYS A CB    1 
ATOM   9339  S  SG    . CYS C 2 347 ? 397.074 386.169 262.506 1.00 122.15 ? 347 CYS A SG    1 
ATOM   9340  N  N     . PRO C 2 348 ? 396.948 389.002 259.213 1.00 98.76  ? 348 PRO A N     1 
ATOM   9341  C  CA    . PRO C 2 348 ? 395.777 389.331 258.377 1.00 99.16  ? 348 PRO A CA    1 
ATOM   9342  C  C     . PRO C 2 348 ? 394.714 388.248 258.346 1.00 98.38  ? 348 PRO A C     1 
ATOM   9343  O  O     . PRO C 2 348 ? 393.541 388.567 258.117 1.00 101.60 ? 348 PRO A O     1 
ATOM   9344  C  CB    . PRO C 2 348 ? 396.383 389.543 256.982 1.00 104.14 ? 348 PRO A CB    1 
ATOM   9345  C  CG    . PRO C 2 348 ? 397.828 389.736 257.197 1.00 105.68 ? 348 PRO A CG    1 
ATOM   9346  C  CD    . PRO C 2 348 ? 398.178 388.943 258.401 1.00 101.43 ? 348 PRO A CD    1 
ATOM   9347  N  N     . THR C 2 349 ? 395.086 386.990 258.570 1.00 106.96 ? 349 THR A N     1 
ATOM   9348  C  CA    . THR C 2 349 ? 394.184 385.840 258.532 1.00 110.51 ? 349 THR A CA    1 
ATOM   9349  C  C     . THR C 2 349 ? 394.155 385.252 259.938 1.00 113.84 ? 349 THR A C     1 
ATOM   9350  O  O     . THR C 2 349 ? 394.931 384.351 260.262 1.00 116.60 ? 349 THR A O     1 
ATOM   9351  C  CB    . THR C 2 349 ? 394.655 384.821 257.506 1.00 114.43 ? 349 THR A CB    1 
ATOM   9352  O  OG1   . THR C 2 349 ? 396.060 384.595 257.667 1.00 109.31 ? 349 THR A OG1   1 
ATOM   9353  C  CG2   . THR C 2 349 ? 394.384 385.321 256.092 1.00 115.01 ? 349 THR A CG2   1 
ATOM   9354  N  N     . GLY C 2 350 ? 393.252 385.769 260.770 1.00 104.59 ? 350 GLY A N     1 
ATOM   9355  C  CA    . GLY C 2 350 ? 393.203 385.421 262.176 1.00 106.14 ? 350 GLY A CA    1 
ATOM   9356  C  C     . GLY C 2 350 ? 392.318 384.257 262.555 1.00 103.11 ? 350 GLY A C     1 
ATOM   9357  O  O     . GLY C 2 350 ? 392.185 383.986 263.752 1.00 108.93 ? 350 GLY A O     1 
ATOM   9358  N  N     . PHE C 2 351 ? 391.717 383.565 261.586 1.00 98.07  ? 351 PHE A N     1 
ATOM   9359  C  CA    . PHE C 2 351 ? 390.700 382.550 261.841 1.00 98.48  ? 351 PHE A CA    1 
ATOM   9360  C  C     . PHE C 2 351 ? 391.087 381.208 261.236 1.00 108.13 ? 351 PHE A C     1 
ATOM   9361  O  O     . PHE C 2 351 ? 391.421 381.123 260.050 1.00 112.79 ? 351 PHE A O     1 
ATOM   9362  C  CB    . PHE C 2 351 ? 389.354 382.999 261.286 1.00 94.08  ? 351 PHE A CB    1 
ATOM   9363  C  CG    . PHE C 2 351 ? 388.900 384.320 261.816 1.00 101.23 ? 351 PHE A CG    1 
ATOM   9364  C  CD1   . PHE C 2 351 ? 388.253 384.404 263.034 1.00 98.03  ? 351 PHE A CD1   1 
ATOM   9365  C  CD2   . PHE C 2 351 ? 389.100 385.477 261.088 1.00 114.53 ? 351 PHE A CD2   1 
ATOM   9366  C  CE1   . PHE C 2 351 ? 387.824 385.620 263.521 1.00 105.06 ? 351 PHE A CE1   1 
ATOM   9367  C  CE2   . PHE C 2 351 ? 388.673 386.694 261.571 1.00 114.04 ? 351 PHE A CE2   1 
ATOM   9368  C  CZ    . PHE C 2 351 ? 388.033 386.766 262.787 1.00 112.15 ? 351 PHE A CZ    1 
ATOM   9369  N  N     . LYS C 2 352 ? 391.038 380.172 262.068 1.00 111.87 ? 352 LYS A N     1 
ATOM   9370  C  CA    . LYS C 2 352 ? 391.085 378.775 261.659 1.00 108.77 ? 352 LYS A CA    1 
ATOM   9371  C  C     . LYS C 2 352 ? 389.671 378.225 261.785 1.00 108.87 ? 352 LYS A C     1 
ATOM   9372  O  O     . LYS C 2 352 ? 388.993 378.496 262.779 1.00 110.39 ? 352 LYS A O     1 
ATOM   9373  C  CB    . LYS C 2 352 ? 392.070 378.004 262.546 1.00 107.84 ? 352 LYS A CB    1 
ATOM   9374  C  CG    . LYS C 2 352 ? 392.004 376.470 262.526 1.00 109.53 ? 352 LYS A CG    1 
ATOM   9375  C  CD    . LYS C 2 352 ? 392.197 375.885 261.143 1.00 104.92 ? 352 LYS A CD    1 
ATOM   9376  C  CE    . LYS C 2 352 ? 392.642 374.438 261.224 1.00 105.25 ? 352 LYS A CE    1 
ATOM   9377  N  NZ    . LYS C 2 352 ? 392.359 373.677 259.977 1.00 111.18 ? 352 LYS A NZ    1 
ATOM   9378  N  N     . VAL C 2 353 ? 389.220 377.486 260.772 1.00 100.96 ? 353 VAL A N     1 
ATOM   9379  C  CA    . VAL C 2 353 ? 387.865 376.946 260.712 1.00 97.31  ? 353 VAL A CA    1 
ATOM   9380  C  C     . VAL C 2 353 ? 387.946 375.430 260.635 1.00 100.92 ? 353 VAL A C     1 
ATOM   9381  O  O     . VAL C 2 353 ? 388.740 374.879 259.865 1.00 103.66 ? 353 VAL A O     1 
ATOM   9382  C  CB    . VAL C 2 353 ? 387.075 377.510 259.512 1.00 99.66  ? 353 VAL A CB    1 
ATOM   9383  C  CG1   . VAL C 2 353 ? 385.587 377.171 259.636 1.00 100.45 ? 353 VAL A CG1   1 
ATOM   9384  C  CG2   . VAL C 2 353 ? 387.275 379.018 259.406 1.00 104.08 ? 353 VAL A CG2   1 
ATOM   9385  N  N     . GLY C 2 354 ? 387.127 374.765 261.447 1.00 108.40 ? 354 GLY A N     1 
ATOM   9386  C  CA    . GLY C 2 354 ? 386.939 373.330 261.371 1.00 107.23 ? 354 GLY A CA    1 
ATOM   9387  C  C     . GLY C 2 354 ? 385.466 373.003 261.451 1.00 106.89 ? 354 GLY A C     1 
ATOM   9388  O  O     . GLY C 2 354 ? 384.743 373.649 262.209 1.00 111.92 ? 354 GLY A O     1 
ATOM   9389  N  N     . ILE C 2 355 ? 385.005 372.034 260.660 1.00 94.87  ? 355 ILE A N     1 
ATOM   9390  C  CA    . ILE C 2 355 ? 383.606 371.619 260.621 1.00 91.58  ? 355 ILE A CA    1 
ATOM   9391  C  C     . ILE C 2 355 ? 383.566 370.104 260.735 1.00 96.45  ? 355 ILE A C     1 
ATOM   9392  O  O     . ILE C 2 355 ? 384.418 369.413 260.165 1.00 105.85 ? 355 ILE A O     1 
ATOM   9393  C  CB    . ILE C 2 355 ? 382.895 372.079 259.326 1.00 90.01  ? 355 ILE A CB    1 
ATOM   9394  C  CG1   . ILE C 2 355 ? 382.785 373.605 259.252 1.00 93.87  ? 355 ILE A CG1   1 
ATOM   9395  C  CG2   . ILE C 2 355 ? 381.496 371.469 259.225 1.00 94.29  ? 355 ILE A CG2   1 
ATOM   9396  C  CD1   . ILE C 2 355 ? 382.711 374.128 257.836 1.00 97.65  ? 355 ILE A CD1   1 
ATOM   9397  N  N     . ASN C 2 356 ? 382.593 369.587 261.484 1.00 103.46 ? 356 ASN A N     1 
ATOM   9398  C  CA    . ASN C 2 356 ? 382.312 368.156 261.420 1.00 103.62 ? 356 ASN A CA    1 
ATOM   9399  C  C     . ASN C 2 356 ? 380.824 367.903 261.629 1.00 110.35 ? 356 ASN A C     1 
ATOM   9400  O  O     . ASN C 2 356 ? 380.075 368.768 262.092 1.00 115.22 ? 356 ASN A O     1 
ATOM   9401  C  CB    . ASN C 2 356 ? 383.159 367.361 262.421 1.00 96.58  ? 356 ASN A CB    1 
ATOM   9402  C  CG    . ASN C 2 356 ? 382.648 367.469 263.828 1.00 104.49 ? 356 ASN A CG    1 
ATOM   9403  O  OD1   . ASN C 2 356 ? 382.310 368.553 264.287 1.00 116.83 ? 356 ASN A OD1   1 
ATOM   9404  N  ND2   . ASN C 2 356 ? 382.586 366.342 264.527 1.00 105.51 ? 356 ASN A ND2   1 
ATOM   9405  N  N     . TYR C 2 357 ? 380.400 366.698 261.248 1.00 105.97 ? 357 TYR A N     1 
ATOM   9406  C  CA    . TYR C 2 357 ? 378.977 366.418 261.102 1.00 106.75 ? 357 TYR A CA    1 
ATOM   9407  C  C     . TYR C 2 357 ? 378.305 366.039 262.416 1.00 106.81 ? 357 TYR A C     1 
ATOM   9408  O  O     . TYR C 2 357 ? 377.102 366.268 262.570 1.00 102.59 ? 357 TYR A O     1 
ATOM   9409  C  CB    . TYR C 2 357 ? 378.775 365.303 260.077 1.00 104.28 ? 357 TYR A CB    1 
ATOM   9410  C  CG    . TYR C 2 357 ? 379.476 365.554 258.762 1.00 101.51 ? 357 TYR A CG    1 
ATOM   9411  C  CD1   . TYR C 2 357 ? 379.141 366.644 257.971 1.00 98.23  ? 357 TYR A CD1   1 
ATOM   9412  C  CD2   . TYR C 2 357 ? 380.470 364.698 258.310 1.00 109.69 ? 357 TYR A CD2   1 
ATOM   9413  C  CE1   . TYR C 2 357 ? 379.779 366.876 256.768 1.00 105.35 ? 357 TYR A CE1   1 
ATOM   9414  C  CE2   . TYR C 2 357 ? 381.112 364.921 257.108 1.00 114.32 ? 357 TYR A CE2   1 
ATOM   9415  C  CZ    . TYR C 2 357 ? 380.764 366.011 256.342 1.00 114.14 ? 357 TYR A CZ    1 
ATOM   9416  O  OH    . TYR C 2 357 ? 381.404 366.235 255.146 1.00 112.98 ? 357 TYR A OH    1 
ATOM   9417  N  N     . GLN C 2 358 ? 379.040 365.472 263.362 1.00 100.16 ? 358 GLN A N     1 
ATOM   9418  C  CA    . GLN C 2 358 ? 378.418 364.941 264.571 1.00 95.62  ? 358 GLN A CA    1 
ATOM   9419  C  C     . GLN C 2 358 ? 377.956 366.085 265.473 1.00 94.85  ? 358 GLN A C     1 
ATOM   9420  O  O     . GLN C 2 358 ? 378.802 366.864 265.925 1.00 97.86  ? 358 GLN A O     1 
ATOM   9421  C  CB    . GLN C 2 358 ? 379.414 364.053 265.317 1.00 99.22  ? 358 GLN A CB    1 
ATOM   9422  C  CG    . GLN C 2 358 ? 378.836 363.268 266.499 1.00 97.45  ? 358 GLN A CG    1 
ATOM   9423  C  CD    . GLN C 2 358 ? 377.823 362.222 266.082 1.00 100.27 ? 358 GLN A CD    1 
ATOM   9424  O  OE1   . GLN C 2 358 ? 377.772 361.819 264.920 1.00 99.45  ? 358 GLN A OE1   1 
ATOM   9425  N  NE2   . GLN C 2 358 ? 377.004 361.782 267.029 1.00 102.23 ? 358 GLN A NE2   1 
ATOM   9426  N  N     . PRO C 2 359 ? 376.665 366.228 265.787 1.00 103.68 ? 359 PRO A N     1 
ATOM   9427  C  CA    . PRO C 2 359 ? 376.271 367.244 266.773 1.00 105.51 ? 359 PRO A CA    1 
ATOM   9428  C  C     . PRO C 2 359 ? 376.650 366.805 268.175 1.00 105.12 ? 359 PRO A C     1 
ATOM   9429  O  O     . PRO C 2 359 ? 376.998 365.634 268.389 1.00 106.13 ? 359 PRO A O     1 
ATOM   9430  C  CB    . PRO C 2 359 ? 374.747 367.330 266.606 1.00 103.50 ? 359 PRO A CB    1 
ATOM   9431  C  CG    . PRO C 2 359 ? 374.360 366.019 266.098 1.00 106.72 ? 359 PRO A CG    1 
ATOM   9432  C  CD    . PRO C 2 359 ? 375.468 365.592 265.197 1.00 105.03 ? 359 PRO A CD    1 
ATOM   9433  N  N     . PRO C 2 360 ? 376.604 367.702 269.159 1.00 109.27 ? 360 PRO A N     1 
ATOM   9434  C  CA    . PRO C 2 360 ? 376.921 367.292 270.528 1.00 108.87 ? 360 PRO A CA    1 
ATOM   9435  C  C     . PRO C 2 360 ? 375.803 366.450 271.120 1.00 115.82 ? 360 PRO A C     1 
ATOM   9436  O  O     . PRO C 2 360 ? 374.647 366.517 270.696 1.00 119.42 ? 360 PRO A O     1 
ATOM   9437  C  CB    . PRO C 2 360 ? 377.064 368.622 271.268 1.00 104.83 ? 360 PRO A CB    1 
ATOM   9438  C  CG    . PRO C 2 360 ? 376.106 369.505 270.567 1.00 107.62 ? 360 PRO A CG    1 
ATOM   9439  C  CD    . PRO C 2 360 ? 376.184 369.116 269.112 1.00 110.90 ? 360 PRO A CD    1 
ATOM   9440  N  N     . THR C 2 361 ? 376.169 365.653 272.121 1.00 118.43 ? 361 THR A N     1 
ATOM   9441  C  CA    . THR C 2 361 ? 375.233 364.824 272.871 1.00 120.48 ? 361 THR A CA    1 
ATOM   9442  C  C     . THR C 2 361 ? 375.025 365.436 274.246 1.00 120.66 ? 361 THR A C     1 
ATOM   9443  O  O     . THR C 2 361 ? 375.996 365.779 274.929 1.00 121.93 ? 361 THR A O     1 
ATOM   9444  C  CB    . THR C 2 361 ? 375.750 363.393 273.021 1.00 117.88 ? 361 THR A CB    1 
ATOM   9445  O  OG1   . THR C 2 361 ? 376.995 363.410 273.728 1.00 115.87 ? 361 THR A OG1   1 
ATOM   9446  C  CG2   . THR C 2 361 ? 375.942 362.742 271.658 1.00 117.33 ? 361 THR A CG2   1 
ATOM   9447  N  N     . VAL C 2 362 ? 373.766 365.568 274.647 1.00 124.14 ? 362 VAL A N     1 
ATOM   9448  C  CA    . VAL C 2 362 ? 373.421 366.064 275.976 1.00 123.86 ? 362 VAL A CA    1 
ATOM   9449  C  C     . VAL C 2 362 ? 373.464 364.897 276.952 1.00 126.07 ? 362 VAL A C     1 
ATOM   9450  O  O     . VAL C 2 362 ? 372.907 363.826 276.683 1.00 126.58 ? 362 VAL A O     1 
ATOM   9451  C  CB    . VAL C 2 362 ? 372.042 366.756 275.984 1.00 124.51 ? 362 VAL A CB    1 
ATOM   9452  C  CG1   . VAL C 2 362 ? 372.083 368.016 275.134 1.00 126.39 ? 362 VAL A CG1   1 
ATOM   9453  C  CG2   . VAL C 2 362 ? 370.886 365.827 275.537 1.00 122.15 ? 362 VAL A CG2   1 
ATOM   9454  N  N     . VAL C 2 363 ? 374.140 365.095 278.078 1.00 128.60 ? 363 VAL A N     1 
ATOM   9455  C  CA    . VAL C 2 363 ? 374.257 364.057 279.099 1.00 131.34 ? 363 VAL A CA    1 
ATOM   9456  C  C     . VAL C 2 363 ? 372.880 363.915 279.743 1.00 131.74 ? 363 VAL A C     1 
ATOM   9457  O  O     . VAL C 2 363 ? 372.148 364.913 279.813 1.00 126.73 ? 363 VAL A O     1 
ATOM   9458  C  CB    . VAL C 2 363 ? 375.342 364.403 280.134 1.00 128.35 ? 363 VAL A CB    1 
ATOM   9459  C  CG1   . VAL C 2 363 ? 375.542 363.254 281.127 1.00 124.96 ? 363 VAL A CG1   1 
ATOM   9460  C  CG2   . VAL C 2 363 ? 376.661 364.743 279.436 1.00 123.68 ? 363 VAL A CG2   1 
ATOM   9461  N  N     . PRO C 2 364 ? 372.459 362.729 280.201 1.00 146.43 ? 364 PRO A N     1 
ATOM   9462  C  CA    . PRO C 2 364 ? 371.208 362.663 280.967 1.00 145.88 ? 364 PRO A CA    1 
ATOM   9463  C  C     . PRO C 2 364 ? 371.315 363.453 282.263 1.00 145.59 ? 364 PRO A C     1 
ATOM   9464  O  O     . PRO C 2 364 ? 372.357 363.466 282.921 1.00 142.50 ? 364 PRO A O     1 
ATOM   9465  C  CB    . PRO C 2 364 ? 371.026 361.164 281.230 1.00 144.80 ? 364 PRO A CB    1 
ATOM   9466  C  CG    . PRO C 2 364 ? 371.822 360.494 280.184 1.00 144.99 ? 364 PRO A CG    1 
ATOM   9467  C  CD    . PRO C 2 364 ? 373.002 361.378 279.963 1.00 142.94 ? 364 PRO A CD    1 
ATOM   9468  N  N     . GLY C 2 365 ? 370.221 364.118 282.624 1.00 157.78 ? 365 GLY A N     1 
ATOM   9469  C  CA    . GLY C 2 365 ? 370.223 364.971 283.794 1.00 156.80 ? 365 GLY A CA    1 
ATOM   9470  C  C     . GLY C 2 365 ? 371.064 366.221 283.673 1.00 156.77 ? 365 GLY A C     1 
ATOM   9471  O  O     . GLY C 2 365 ? 371.355 366.852 284.693 1.00 155.18 ? 365 GLY A O     1 
ATOM   9472  N  N     . GLY C 2 366 ? 371.465 366.603 282.456 1.00 153.63 ? 366 GLY A N     1 
ATOM   9473  C  CA    . GLY C 2 366 ? 372.290 367.775 282.272 1.00 151.09 ? 366 GLY A CA    1 
ATOM   9474  C  C     . GLY C 2 366 ? 371.490 369.061 282.283 1.00 152.36 ? 366 GLY A C     1 
ATOM   9475  O  O     . GLY C 2 366 ? 370.259 369.062 282.273 1.00 153.62 ? 366 GLY A O     1 
ATOM   9476  N  N     . ASP C 2 367 ? 372.227 370.173 282.301 1.00 135.97 ? 367 ASP A N     1 
ATOM   9477  C  CA    . ASP C 2 367 ? 371.649 371.511 282.317 1.00 135.50 ? 367 ASP A CA    1 
ATOM   9478  C  C     . ASP C 2 367 ? 371.619 372.175 280.946 1.00 133.26 ? 367 ASP A C     1 
ATOM   9479  O  O     . ASP C 2 367 ? 370.880 373.149 280.769 1.00 132.14 ? 367 ASP A O     1 
ATOM   9480  C  CB    . ASP C 2 367 ? 372.435 372.403 283.286 1.00 137.01 ? 367 ASP A CB    1 
ATOM   9481  C  CG    . ASP C 2 367 ? 372.094 372.132 284.743 1.00 137.82 ? 367 ASP A CG    1 
ATOM   9482  O  OD1   . ASP C 2 367 ? 371.376 371.150 285.025 1.00 137.61 ? 367 ASP A OD1   1 
ATOM   9483  O  OD2   . ASP C 2 367 ? 372.559 372.895 285.613 1.00 137.15 ? 367 ASP A OD2   1 
ATOM   9484  N  N     . LEU C 2 368 ? 372.394 371.680 279.983 1.00 129.54 ? 368 LEU A N     1 
ATOM   9485  C  CA    . LEU C 2 368 ? 372.421 372.256 278.647 1.00 130.73 ? 368 LEU A CA    1 
ATOM   9486  C  C     . LEU C 2 368 ? 371.258 371.738 277.809 1.00 131.24 ? 368 LEU A C     1 
ATOM   9487  O  O     . LEU C 2 368 ? 370.728 370.649 278.045 1.00 129.91 ? 368 LEU A O     1 
ATOM   9488  C  CB    . LEU C 2 368 ? 373.742 371.929 277.948 1.00 131.08 ? 368 LEU A CB    1 
ATOM   9489  C  CG    . LEU C 2 368 ? 374.937 372.836 278.254 1.00 132.68 ? 368 LEU A CG    1 
ATOM   9490  C  CD1   . LEU C 2 368 ? 376.223 372.191 277.767 1.00 128.86 ? 368 LEU A CD1   1 
ATOM   9491  C  CD2   . LEU C 2 368 ? 374.769 374.209 277.616 1.00 131.78 ? 368 LEU A CD2   1 
ATOM   9492  N  N     . ALA C 2 369 ? 370.871 372.536 276.818 1.00 139.49 ? 369 ALA A N     1 
ATOM   9493  C  CA    . ALA C 2 369 ? 369.782 372.197 275.916 1.00 139.51 ? 369 ALA A CA    1 
ATOM   9494  C  C     . ALA C 2 369 ? 370.298 371.385 274.735 1.00 139.31 ? 369 ALA A C     1 
ATOM   9495  O  O     . ALA C 2 369 ? 371.448 371.529 274.312 1.00 141.54 ? 369 ALA A O     1 
ATOM   9496  C  CB    . ALA C 2 369 ? 369.094 373.463 275.409 1.00 137.31 ? 369 ALA A CB    1 
ATOM   9497  N  N     . LYS C 2 370 ? 369.432 370.524 274.206 1.00 142.82 ? 370 LYS A N     1 
ATOM   9498  C  CA    . LYS C 2 370 ? 369.766 369.779 273.000 1.00 144.56 ? 370 LYS A CA    1 
ATOM   9499  C  C     . LYS C 2 370 ? 369.748 370.722 271.804 1.00 145.02 ? 370 LYS A C     1 
ATOM   9500  O  O     . LYS C 2 370 ? 368.780 371.460 271.599 1.00 143.58 ? 370 LYS A O     1 
ATOM   9501  C  CB    . LYS C 2 370 ? 368.778 368.626 272.802 1.00 142.73 ? 370 LYS A CB    1 
ATOM   9502  C  CG    . LYS C 2 370 ? 368.989 367.758 271.550 1.00 143.57 ? 370 LYS A CG    1 
ATOM   9503  C  CD    . LYS C 2 370 ? 370.383 367.144 271.480 1.00 144.11 ? 370 LYS A CD    1 
ATOM   9504  C  CE    . LYS C 2 370 ? 370.506 366.181 270.312 1.00 141.18 ? 370 LYS A CE    1 
ATOM   9505  N  NZ    . LYS C 2 370 ? 371.837 365.517 270.277 1.00 140.36 ? 370 LYS A NZ    1 
ATOM   9506  N  N     . VAL C 2 371 ? 370.824 370.694 271.019 1.00 137.28 ? 371 VAL A N     1 
ATOM   9507  C  CA    . VAL C 2 371 ? 371.023 371.611 269.900 1.00 133.18 ? 371 VAL A CA    1 
ATOM   9508  C  C     . VAL C 2 371 ? 371.600 370.838 268.724 1.00 136.90 ? 371 VAL A C     1 
ATOM   9509  O  O     . VAL C 2 371 ? 372.479 369.987 268.897 1.00 137.92 ? 371 VAL A O     1 
ATOM   9510  C  CB    . VAL C 2 371 ? 371.942 372.794 270.283 1.00 131.08 ? 371 VAL A CB    1 
ATOM   9511  C  CG1   . VAL C 2 371 ? 371.278 373.655 271.343 1.00 133.56 ? 371 VAL A CG1   1 
ATOM   9512  C  CG2   . VAL C 2 371 ? 373.325 372.315 270.771 1.00 130.53 ? 371 VAL A CG2   1 
ATOM   9513  N  N     . GLN C 2 372 ? 371.103 371.140 267.525 1.00 124.62 ? 372 GLN A N     1 
ATOM   9514  C  CA    . GLN C 2 372 ? 371.654 370.568 266.301 1.00 126.51 ? 372 GLN A CA    1 
ATOM   9515  C  C     . GLN C 2 372 ? 372.934 371.258 265.836 1.00 128.47 ? 372 GLN A C     1 
ATOM   9516  O  O     . GLN C 2 372 ? 373.574 370.756 264.904 1.00 126.40 ? 372 GLN A O     1 
ATOM   9517  C  CB    . GLN C 2 372 ? 370.610 370.609 265.175 1.00 125.41 ? 372 GLN A CB    1 
ATOM   9518  C  CG    . GLN C 2 372 ? 370.036 371.989 264.842 1.00 125.56 ? 372 GLN A CG    1 
ATOM   9519  C  CD    . GLN C 2 372 ? 368.669 372.208 265.460 1.00 125.97 ? 372 GLN A CD    1 
ATOM   9520  O  OE1   . GLN C 2 372 ? 368.546 372.382 266.672 1.00 123.65 ? 372 GLN A OE1   1 
ATOM   9521  N  NE2   . GLN C 2 372 ? 367.632 372.200 264.629 1.00 127.59 ? 372 GLN A NE2   1 
ATOM   9522  N  N     . ARG C 2 373 ? 373.316 372.383 266.448 1.00 127.41 ? 373 ARG A N     1 
ATOM   9523  C  CA    . ARG C 2 373 ? 374.522 373.128 266.111 1.00 119.37 ? 373 ARG A CA    1 
ATOM   9524  C  C     . ARG C 2 373 ? 375.304 373.429 267.375 1.00 120.91 ? 373 ARG A C     1 
ATOM   9525  O  O     . ARG C 2 373 ? 374.718 373.701 268.426 1.00 123.04 ? 373 ARG A O     1 
ATOM   9526  C  CB    . ARG C 2 373 ? 374.183 374.444 265.409 1.00 116.94 ? 373 ARG A CB    1 
ATOM   9527  C  CG    . ARG C 2 373 ? 373.807 374.286 263.961 1.00 119.75 ? 373 ARG A CG    1 
ATOM   9528  C  CD    . ARG C 2 373 ? 373.428 375.614 263.334 1.00 120.15 ? 373 ARG A CD    1 
ATOM   9529  N  NE    . ARG C 2 373 ? 372.102 376.055 263.754 1.00 123.36 ? 373 ARG A NE    1 
ATOM   9530  C  CZ    . ARG C 2 373 ? 370.952 375.553 263.318 1.00 124.00 ? 373 ARG A CZ    1 
ATOM   9531  N  NH1   . ARG C 2 373 ? 370.906 374.566 262.434 1.00 123.10 ? 373 ARG A NH1   1 
ATOM   9532  N  NH2   . ARG C 2 373 ? 369.811 376.053 263.785 1.00 124.44 ? 373 ARG A NH2   1 
ATOM   9533  N  N     . ALA C 2 374 ? 376.629 373.383 267.270 1.00 111.74 ? 374 ALA A N     1 
ATOM   9534  C  CA    . ALA C 2 374 ? 377.472 373.839 268.365 1.00 110.56 ? 374 ALA A CA    1 
ATOM   9535  C  C     . ALA C 2 374 ? 378.790 374.322 267.791 1.00 108.23 ? 374 ALA A C     1 
ATOM   9536  O  O     . ALA C 2 374 ? 379.189 373.914 266.700 1.00 111.38 ? 374 ALA A O     1 
ATOM   9537  C  CB    . ALA C 2 374 ? 377.700 372.737 269.402 1.00 112.64 ? 374 ALA A CB    1 
ATOM   9538  N  N     . VAL C 2 375 ? 379.445 375.217 268.527 1.00 100.83 ? 375 VAL A N     1 
ATOM   9539  C  CA    . VAL C 2 375 ? 380.730 375.773 268.131 1.00 97.17  ? 375 VAL A CA    1 
ATOM   9540  C  C     . VAL C 2 375 ? 381.603 375.912 269.368 1.00 102.50 ? 375 VAL A C     1 
ATOM   9541  O  O     . VAL C 2 375 ? 381.132 376.332 270.431 1.00 103.47 ? 375 VAL A O     1 
ATOM   9542  C  CB    . VAL C 2 375 ? 380.571 377.123 267.396 1.00 100.23 ? 375 VAL A CB    1 
ATOM   9543  C  CG1   . VAL C 2 375 ? 379.676 378.087 268.172 1.00 107.45 ? 375 VAL A CG1   1 
ATOM   9544  C  CG2   . VAL C 2 375 ? 381.933 377.747 267.128 1.00 100.45 ? 375 VAL A CG2   1 
ATOM   9545  N  N     . CYS C 2 376 ? 382.872 375.527 269.229 1.00 109.49 ? 376 CYS A N     1 
ATOM   9546  C  CA    . CYS C 2 376 ? 383.889 375.725 270.259 1.00 104.27 ? 376 CYS A CA    1 
ATOM   9547  C  C     . CYS C 2 376 ? 384.928 376.692 269.709 1.00 100.81 ? 376 CYS A C     1 
ATOM   9548  O  O     . CYS C 2 376 ? 385.573 376.401 268.696 1.00 102.07 ? 376 CYS A O     1 
ATOM   9549  C  CB    . CYS C 2 376 ? 384.531 374.402 270.669 1.00 106.60 ? 376 CYS A CB    1 
ATOM   9550  S  SG    . CYS C 2 376 ? 386.029 374.604 271.651 1.00 122.08 ? 376 CYS A SG    1 
ATOM   9551  N  N     . MET C 2 377 ? 385.075 377.838 270.371 1.00 102.42 ? 377 MET A N     1 
ATOM   9552  C  CA    . MET C 2 377 ? 385.982 378.901 269.952 1.00 105.45 ? 377 MET A CA    1 
ATOM   9553  C  C     . MET C 2 377 ? 387.175 378.945 270.898 1.00 106.83 ? 377 MET A C     1 
ATOM   9554  O  O     . MET C 2 377 ? 387.002 378.950 272.121 1.00 114.30 ? 377 MET A O     1 
ATOM   9555  C  CB    . MET C 2 377 ? 385.256 380.246 269.934 1.00 114.30 ? 377 MET A CB    1 
ATOM   9556  C  CG    . MET C 2 377 ? 385.947 381.344 269.144 1.00 113.91 ? 377 MET A CG    1 
ATOM   9557  S  SD    . MET C 2 377 ? 386.946 382.383 270.219 1.00 120.17 ? 377 MET A SD    1 
ATOM   9558  C  CE    . MET C 2 377 ? 385.973 383.882 270.234 1.00 116.70 ? 377 MET A CE    1 
ATOM   9559  N  N     . LEU C 2 378 ? 388.376 378.980 270.324 1.00 100.95 ? 378 LEU A N     1 
ATOM   9560  C  CA    . LEU C 2 378 ? 389.636 378.990 271.057 1.00 98.49  ? 378 LEU A CA    1 
ATOM   9561  C  C     . LEU C 2 378 ? 390.448 380.174 270.560 1.00 96.55  ? 378 LEU A C     1 
ATOM   9562  O  O     . LEU C 2 378 ? 390.834 380.204 269.388 1.00 103.35 ? 378 LEU A O     1 
ATOM   9563  C  CB    . LEU C 2 378 ? 390.400 377.688 270.825 1.00 99.21  ? 378 LEU A CB    1 
ATOM   9564  C  CG    . LEU C 2 378 ? 389.717 376.379 271.230 1.00 106.08 ? 378 LEU A CG    1 
ATOM   9565  C  CD1   . LEU C 2 378 ? 390.678 375.240 271.006 1.00 102.75 ? 378 LEU A CD1   1 
ATOM   9566  C  CD2   . LEU C 2 378 ? 389.242 376.399 272.674 1.00 113.52 ? 378 LEU A CD2   1 
ATOM   9567  N  N     . SER C 2 379 ? 390.723 381.131 271.446 1.00 95.77  ? 379 SER A N     1 
ATOM   9568  C  CA    . SER C 2 379 ? 391.302 382.417 271.067 1.00 103.83 ? 379 SER A CA    1 
ATOM   9569  C  C     . SER C 2 379 ? 392.573 382.678 271.857 1.00 107.54 ? 379 SER A C     1 
ATOM   9570  O  O     . SER C 2 379 ? 392.531 382.811 273.083 1.00 112.06 ? 379 SER A O     1 
ATOM   9571  C  CB    . SER C 2 379 ? 390.301 383.552 271.297 1.00 107.58 ? 379 SER A CB    1 
ATOM   9572  O  OG    . SER C 2 379 ? 389.726 383.469 272.588 1.00 111.52 ? 379 SER A OG    1 
ATOM   9573  N  N     . ASN C 2 380 ? 393.696 382.751 271.148 1.00 93.23  ? 380 ASN A N     1 
ATOM   9574  C  CA    . ASN C 2 380 ? 394.916 383.353 271.654 1.00 93.20  ? 380 ASN A CA    1 
ATOM   9575  C  C     . ASN C 2 380 ? 394.825 384.860 271.464 1.00 94.22  ? 380 ASN A C     1 
ATOM   9576  O  O     . ASN C 2 380 ? 394.702 385.340 270.329 1.00 100.64 ? 380 ASN A O     1 
ATOM   9577  C  CB    . ASN C 2 380 ? 396.135 382.797 270.920 1.00 92.84  ? 380 ASN A CB    1 
ATOM   9578  C  CG    . ASN C 2 380 ? 397.411 382.966 271.707 1.00 99.53  ? 380 ASN A CG    1 
ATOM   9579  O  OD1   . ASN C 2 380 ? 397.499 383.818 272.589 1.00 109.73 ? 380 ASN A OD1   1 
ATOM   9580  N  ND2   . ASN C 2 380 ? 398.409 382.150 271.399 1.00 95.10  ? 380 ASN A ND2   1 
ATOM   9581  N  N     . THR C 2 381 ? 394.910 385.589 272.577 1.00 94.02  ? 381 THR A N     1 
ATOM   9582  C  CA    . THR C 2 381 ? 394.675 387.025 272.633 1.00 94.74  ? 381 THR A CA    1 
ATOM   9583  C  C     . THR C 2 381 ? 395.507 387.607 273.766 1.00 96.46  ? 381 THR A C     1 
ATOM   9584  O  O     . THR C 2 381 ? 395.925 386.896 274.683 1.00 104.76 ? 381 THR A O     1 
ATOM   9585  C  CB    . THR C 2 381 ? 393.182 387.341 272.808 1.00 99.47  ? 381 THR A CB    1 
ATOM   9586  O  OG1   . THR C 2 381 ? 392.932 388.712 272.471 1.00 104.27 ? 381 THR A OG1   1 
ATOM   9587  C  CG2   . THR C 2 381 ? 392.692 387.028 274.221 1.00 92.66  ? 381 THR A CG2   1 
ATOM   9588  N  N     . THR C 2 382 ? 395.741 388.917 273.688 1.00 91.43  ? 382 THR A N     1 
ATOM   9589  C  CA    . THR C 2 382 ? 396.619 389.614 274.621 1.00 95.57  ? 382 THR A CA    1 
ATOM   9590  C  C     . THR C 2 382 ? 395.921 390.065 275.900 1.00 96.99  ? 382 THR A C     1 
ATOM   9591  O  O     . THR C 2 382 ? 396.577 390.670 276.753 1.00 100.18 ? 382 THR A O     1 
ATOM   9592  C  CB    . THR C 2 382 ? 397.242 390.837 273.941 1.00 97.81  ? 382 THR A CB    1 
ATOM   9593  O  OG1   . THR C 2 382 ? 396.211 391.760 273.572 1.00 100.52 ? 382 THR A OG1   1 
ATOM   9594  C  CG2   . THR C 2 382 ? 398.022 390.430 272.699 1.00 95.30  ? 382 THR A CG2   1 
ATOM   9595  N  N     . ALA C 2 383 ? 394.622 389.802 276.055 1.00 103.33 ? 383 ALA A N     1 
ATOM   9596  C  CA    . ALA C 2 383 ? 393.918 390.217 277.264 1.00 109.05 ? 383 ALA A CA    1 
ATOM   9597  C  C     . ALA C 2 383 ? 394.448 389.509 278.504 1.00 109.97 ? 383 ALA A C     1 
ATOM   9598  O  O     . ALA C 2 383 ? 394.475 390.100 279.588 1.00 113.57 ? 383 ALA A O     1 
ATOM   9599  C  CB    . ALA C 2 383 ? 392.421 389.958 277.105 1.00 112.43 ? 383 ALA A CB    1 
ATOM   9600  N  N     . ILE C 2 384 ? 394.874 388.250 278.366 1.00 102.89 ? 384 ILE A N     1 
ATOM   9601  C  CA    . ILE C 2 384 ? 395.420 387.498 279.500 1.00 107.04 ? 384 ILE A CA    1 
ATOM   9602  C  C     . ILE C 2 384 ? 396.772 388.017 279.978 1.00 107.54 ? 384 ILE A C     1 
ATOM   9603  O  O     . ILE C 2 384 ? 397.263 387.566 281.024 1.00 114.65 ? 384 ILE A O     1 
ATOM   9604  C  CB    . ILE C 2 384 ? 395.553 385.981 279.212 1.00 104.63 ? 384 ILE A CB    1 
ATOM   9605  C  CG1   . ILE C 2 384 ? 396.235 385.689 277.857 1.00 102.09 ? 384 ILE A CG1   1 
ATOM   9606  C  CG2   . ILE C 2 384 ? 394.165 385.330 279.321 1.00 110.06 ? 384 ILE A CG2   1 
ATOM   9607  C  CD1   . ILE C 2 384 ? 396.473 384.222 277.562 1.00 108.10 ? 384 ILE A CD1   1 
ATOM   9608  N  N     . ALA C 2 385 ? 397.395 388.951 279.252 1.00 94.16  ? 385 ALA A N     1 
ATOM   9609  C  CA    . ALA C 2 385 ? 398.531 389.675 279.810 1.00 97.89  ? 385 ALA A CA    1 
ATOM   9610  C  C     . ALA C 2 385 ? 398.135 390.428 281.073 1.00 102.41 ? 385 ALA A C     1 
ATOM   9611  O  O     . ALA C 2 385 ? 398.925 390.511 282.019 1.00 103.38 ? 385 ALA A O     1 
ATOM   9612  C  CB    . ALA C 2 385 ? 399.100 390.638 278.772 1.00 98.83  ? 385 ALA A CB    1 
ATOM   9613  N  N     . GLU C 2 386 ? 396.912 390.964 281.113 1.00 114.81 ? 386 GLU A N     1 
ATOM   9614  C  CA    . GLU C 2 386 ? 396.404 391.580 282.336 1.00 115.25 ? 386 GLU A CA    1 
ATOM   9615  C  C     . GLU C 2 386 ? 396.325 390.563 283.466 1.00 113.41 ? 386 GLU A C     1 
ATOM   9616  O  O     . GLU C 2 386 ? 396.639 390.872 284.622 1.00 119.97 ? 386 GLU A O     1 
ATOM   9617  C  CB    . GLU C 2 386 ? 395.019 392.181 282.090 1.00 117.77 ? 386 GLU A CB    1 
ATOM   9618  C  CG    . GLU C 2 386 ? 394.940 393.233 280.989 1.00 121.25 ? 386 GLU A CG    1 
ATOM   9619  C  CD    . GLU C 2 386 ? 395.724 394.490 281.306 1.00 125.79 ? 386 GLU A CD    1 
ATOM   9620  O  OE1   . GLU C 2 386 ? 396.053 394.710 282.491 1.00 126.53 ? 386 GLU A OE1   1 
ATOM   9621  O  OE2   . GLU C 2 386 ? 396.006 395.263 280.367 1.00 125.69 ? 386 GLU A OE2   1 
ATOM   9622  N  N     . ALA C 2 387 ? 395.895 389.343 283.150 1.00 95.64  ? 387 ALA A N     1 
ATOM   9623  C  CA    . ALA C 2 387 ? 395.743 388.320 284.176 1.00 100.61 ? 387 ALA A CA    1 
ATOM   9624  C  C     . ALA C 2 387 ? 397.096 387.888 284.729 1.00 103.47 ? 387 ALA A C     1 
ATOM   9625  O  O     . ALA C 2 387 ? 397.252 387.710 285.945 1.00 110.27 ? 387 ALA A O     1 
ATOM   9626  C  CB    . ALA C 2 387 ? 394.985 387.131 283.597 1.00 98.25  ? 387 ALA A CB    1 
ATOM   9627  N  N     . TRP C 2 388 ? 398.085 387.706 283.853 1.00 106.20 ? 388 TRP A N     1 
ATOM   9628  C  CA    . TRP C 2 388 ? 399.441 387.456 284.334 1.00 107.67 ? 388 TRP A CA    1 
ATOM   9629  C  C     . TRP C 2 388 ? 400.009 388.639 285.104 1.00 108.87 ? 388 TRP A C     1 
ATOM   9630  O  O     . TRP C 2 388 ? 400.794 388.435 286.032 1.00 113.06 ? 388 TRP A O     1 
ATOM   9631  C  CB    . TRP C 2 388 ? 400.366 387.089 283.175 1.00 108.08 ? 388 TRP A CB    1 
ATOM   9632  C  CG    . TRP C 2 388 ? 400.229 385.679 282.683 1.00 112.08 ? 388 TRP A CG    1 
ATOM   9633  C  CD1   . TRP C 2 388 ? 400.317 384.534 283.426 1.00 111.06 ? 388 TRP A CD1   1 
ATOM   9634  C  CD2   . TRP C 2 388 ? 399.951 385.265 281.348 1.00 111.96 ? 388 TRP A CD2   1 
ATOM   9635  N  NE1   . TRP C 2 388 ? 400.130 383.436 282.629 1.00 104.67 ? 388 TRP A NE1   1 
ATOM   9636  C  CE2   . TRP C 2 388 ? 399.900 383.858 281.348 1.00 111.45 ? 388 TRP A CE2   1 
ATOM   9637  C  CE3   . TRP C 2 388 ? 399.748 385.946 280.150 1.00 113.43 ? 388 TRP A CE3   1 
ATOM   9638  C  CZ2   . TRP C 2 388 ? 399.654 383.125 280.196 1.00 116.75 ? 388 TRP A CZ2   1 
ATOM   9639  C  CZ3   . TRP C 2 388 ? 399.503 385.221 279.017 1.00 116.01 ? 388 TRP A CZ3   1 
ATOM   9640  C  CH2   . TRP C 2 388 ? 399.461 383.825 279.042 1.00 119.80 ? 388 TRP A CH2   1 
ATOM   9641  N  N     . ALA C 2 389 ? 399.637 389.870 284.750 1.00 101.01 ? 389 ALA A N     1 
ATOM   9642  C  CA    . ALA C 2 389 ? 400.059 391.011 285.556 1.00 101.15 ? 389 ALA A CA    1 
ATOM   9643  C  C     . ALA C 2 389 ? 399.478 390.926 286.961 1.00 105.37 ? 389 ALA A C     1 
ATOM   9644  O  O     . ALA C 2 389 ? 400.175 391.187 287.948 1.00 109.57 ? 389 ALA A O     1 
ATOM   9645  C  CB    . ALA C 2 389 ? 399.647 392.317 284.880 1.00 100.58 ? 389 ALA A CB    1 
ATOM   9646  N  N     . ARG C 2 390 ? 398.203 390.543 287.064 1.00 113.32 ? 390 ARG A N     1 
ATOM   9647  C  CA    . ARG C 2 390 ? 397.571 390.352 288.367 1.00 109.40 ? 390 ARG A CA    1 
ATOM   9648  C  C     . ARG C 2 390 ? 398.284 389.272 289.172 1.00 112.57 ? 390 ARG A C     1 
ATOM   9649  O  O     . ARG C 2 390 ? 398.580 389.452 290.362 1.00 116.46 ? 390 ARG A O     1 
ATOM   9650  C  CB    . ARG C 2 390 ? 396.102 389.975 288.174 1.00 115.08 ? 390 ARG A CB    1 
ATOM   9651  C  CG    . ARG C 2 390 ? 395.239 390.153 289.419 1.00 120.67 ? 390 ARG A CG    1 
ATOM   9652  C  CD    . ARG C 2 390 ? 393.965 389.302 289.422 1.00 121.96 ? 390 ARG A CD    1 
ATOM   9653  N  NE    . ARG C 2 390 ? 393.431 388.988 288.095 1.00 123.88 ? 390 ARG A NE    1 
ATOM   9654  C  CZ    . ARG C 2 390 ? 393.596 387.847 287.430 1.00 124.39 ? 390 ARG A CZ    1 
ATOM   9655  N  NH1   . ARG C 2 390 ? 394.397 386.884 287.865 1.00 122.01 ? 390 ARG A NH1   1 
ATOM   9656  N  NH2   . ARG C 2 390 ? 392.934 387.665 286.291 1.00 123.45 ? 390 ARG A NH2   1 
ATOM   9657  N  N     . LEU C 2 391 ? 398.562 388.136 288.532 1.00 101.48 ? 391 LEU A N     1 
ATOM   9658  C  CA    . LEU C 2 391 ? 399.187 387.020 289.237 1.00 96.91  ? 391 LEU A CA    1 
ATOM   9659  C  C     . LEU C 2 391 ? 400.607 387.369 289.668 1.00 98.56  ? 391 LEU A C     1 
ATOM   9660  O  O     . LEU C 2 391 ? 401.029 387.024 290.778 1.00 107.24 ? 391 LEU A O     1 
ATOM   9661  C  CB    . LEU C 2 391 ? 399.174 385.776 288.345 1.00 94.46  ? 391 LEU A CB    1 
ATOM   9662  C  CG    . LEU C 2 391 ? 399.169 384.371 288.958 1.00 95.10  ? 391 LEU A CG    1 
ATOM   9663  C  CD1   . LEU C 2 391 ? 398.007 384.148 289.921 1.00 103.66 ? 391 LEU A CD1   1 
ATOM   9664  C  CD2   . LEU C 2 391 ? 399.127 383.350 287.832 1.00 96.77  ? 391 LEU A CD2   1 
ATOM   9665  N  N     . ASP C 2 392 ? 401.350 388.073 288.812 1.00 98.63  ? 392 ASP A N     1 
ATOM   9666  C  CA    . ASP C 2 392 ? 402.693 388.507 289.170 1.00 101.75 ? 392 ASP A CA    1 
ATOM   9667  C  C     . ASP C 2 392 ? 402.663 389.522 290.303 1.00 109.66 ? 392 ASP A C     1 
ATOM   9668  O  O     . ASP C 2 392 ? 403.547 389.518 291.164 1.00 118.71 ? 392 ASP A O     1 
ATOM   9669  C  CB    . ASP C 2 392 ? 403.395 389.095 287.949 1.00 106.24 ? 392 ASP A CB    1 
ATOM   9670  C  CG    . ASP C 2 392 ? 403.932 388.030 287.019 1.00 117.00 ? 392 ASP A CG    1 
ATOM   9671  O  OD1   . ASP C 2 392 ? 403.344 386.930 286.971 1.00 119.48 ? 392 ASP A OD1   1 
ATOM   9672  O  OD2   . ASP C 2 392 ? 404.942 388.294 286.333 1.00 115.29 ? 392 ASP A OD2   1 
ATOM   9673  N  N     . HIS C 2 393 ? 401.665 390.408 290.318 1.00 105.31 ? 393 HIS A N     1 
ATOM   9674  C  CA    . HIS C 2 393 ? 401.552 391.359 291.419 1.00 104.11 ? 393 HIS A CA    1 
ATOM   9675  C  C     . HIS C 2 393 ? 401.256 390.647 292.734 1.00 105.90 ? 393 HIS A C     1 
ATOM   9676  O  O     . HIS C 2 393 ? 401.813 391.006 293.779 1.00 111.53 ? 393 HIS A O     1 
ATOM   9677  C  CB    . HIS C 2 393 ? 400.468 392.389 291.111 1.00 102.78 ? 393 HIS A CB    1 
ATOM   9678  C  CG    . HIS C 2 393 ? 400.320 393.439 292.166 1.00 107.55 ? 393 HIS A CG    1 
ATOM   9679  N  ND1   . HIS C 2 393 ? 399.096 393.946 292.545 1.00 110.87 ? 393 HIS A ND1   1 
ATOM   9680  C  CD2   . HIS C 2 393 ? 401.242 394.077 292.924 1.00 105.04 ? 393 HIS A CD2   1 
ATOM   9681  C  CE1   . HIS C 2 393 ? 399.271 394.852 293.491 1.00 108.65 ? 393 HIS A CE1   1 
ATOM   9682  N  NE2   . HIS C 2 393 ? 400.564 394.950 293.739 1.00 109.72 ? 393 HIS A NE2   1 
ATOM   9683  N  N     . LYS C 2 394 ? 400.381 389.639 292.702 1.00 93.61  ? 394 LYS A N     1 
ATOM   9684  C  CA    . LYS C 2 394 ? 400.106 388.861 293.908 1.00 88.36  ? 394 LYS A CA    1 
ATOM   9685  C  C     . LYS C 2 394 ? 401.357 388.126 294.383 1.00 95.69  ? 394 LYS A C     1 
ATOM   9686  O  O     . LYS C 2 394 ? 401.650 388.079 295.590 1.00 107.24 ? 394 LYS A O     1 
ATOM   9687  C  CB    . LYS C 2 394 ? 398.972 387.873 293.638 1.00 89.28  ? 394 LYS A CB    1 
ATOM   9688  C  CG    . LYS C 2 394 ? 397.615 388.538 293.423 1.00 95.68  ? 394 LYS A CG    1 
ATOM   9689  C  CD    . LYS C 2 394 ? 396.590 387.593 292.803 1.00 98.29  ? 394 LYS A CD    1 
ATOM   9690  C  CE    . LYS C 2 394 ? 396.040 386.609 293.820 1.00 100.49 ? 394 LYS A CE    1 
ATOM   9691  N  NZ    . LYS C 2 394 ? 394.946 385.773 293.251 1.00 94.83  ? 394 LYS A NZ    1 
ATOM   9692  N  N     . PHE C 2 395 ? 402.110 387.555 293.438 1.00 95.74  ? 395 PHE A N     1 
ATOM   9693  C  CA    . PHE C 2 395 ? 403.369 386.897 293.770 1.00 100.79 ? 395 PHE A CA    1 
ATOM   9694  C  C     . PHE C 2 395 ? 404.353 387.879 294.389 1.00 98.36  ? 395 PHE A C     1 
ATOM   9695  O  O     . PHE C 2 395 ? 405.053 387.541 295.347 1.00 101.04 ? 395 PHE A O     1 
ATOM   9696  C  CB    . PHE C 2 395 ? 403.963 386.263 292.511 1.00 102.64 ? 395 PHE A CB    1 
ATOM   9697  C  CG    . PHE C 2 395 ? 405.193 385.435 292.761 1.00 101.09 ? 395 PHE A CG    1 
ATOM   9698  C  CD1   . PHE C 2 395 ? 405.085 384.094 293.075 1.00 103.39 ? 395 PHE A CD1   1 
ATOM   9699  C  CD2   . PHE C 2 395 ? 406.457 385.990 292.656 1.00 97.06  ? 395 PHE A CD2   1 
ATOM   9700  C  CE1   . PHE C 2 395 ? 406.208 383.330 293.297 1.00 104.06 ? 395 PHE A CE1   1 
ATOM   9701  C  CE2   . PHE C 2 395 ? 407.581 385.230 292.880 1.00 95.14  ? 395 PHE A CE2   1 
ATOM   9702  C  CZ    . PHE C 2 395 ? 407.457 383.899 293.197 1.00 100.76 ? 395 PHE A CZ    1 
ATOM   9703  N  N     . ASP C 2 396 ? 404.429 389.094 293.843 1.00 101.41 ? 396 ASP A N     1 
ATOM   9704  C  CA    . ASP C 2 396 ? 405.314 390.112 294.397 1.00 103.27 ? 396 ASP A CA    1 
ATOM   9705  C  C     . ASP C 2 396 ? 404.910 390.472 295.816 1.00 106.96 ? 396 ASP A C     1 
ATOM   9706  O  O     . ASP C 2 396 ? 405.767 390.617 296.696 1.00 106.68 ? 396 ASP A O     1 
ATOM   9707  C  CB    . ASP C 2 396 ? 405.287 391.361 293.519 1.00 108.36 ? 396 ASP A CB    1 
ATOM   9708  C  CG    . ASP C 2 396 ? 405.928 391.142 292.169 1.00 115.90 ? 396 ASP A CG    1 
ATOM   9709  O  OD1   . ASP C 2 396 ? 406.481 390.048 291.936 1.00 119.40 ? 396 ASP A OD1   1 
ATOM   9710  O  OD2   . ASP C 2 396 ? 405.876 392.067 291.332 1.00 115.63 ? 396 ASP A OD2   1 
ATOM   9711  N  N     . LEU C 2 397 ? 403.604 390.619 296.052 1.00 107.90 ? 397 LEU A N     1 
ATOM   9712  C  CA    . LEU C 2 397 ? 403.125 390.987 297.379 1.00 103.58 ? 397 LEU A CA    1 
ATOM   9713  C  C     . LEU C 2 397 ? 403.471 389.921 298.408 1.00 101.86 ? 397 LEU A C     1 
ATOM   9714  O  O     . LEU C 2 397 ? 403.916 390.243 299.515 1.00 100.21 ? 397 LEU A O     1 
ATOM   9715  C  CB    . LEU C 2 397 ? 401.616 391.222 297.346 1.00 105.32 ? 397 LEU A CB    1 
ATOM   9716  C  CG    . LEU C 2 397 ? 401.145 392.527 296.699 1.00 105.93 ? 397 LEU A CG    1 
ATOM   9717  C  CD1   . LEU C 2 397 ? 399.665 392.442 296.360 1.00 104.50 ? 397 LEU A CD1   1 
ATOM   9718  C  CD2   . LEU C 2 397 ? 401.416 393.723 297.602 1.00 105.10 ? 397 LEU A CD2   1 
ATOM   9719  N  N     . MET C 2 398 ? 403.286 388.643 298.063 1.00 98.47  ? 398 MET A N     1 
ATOM   9720  C  CA    . MET C 2 398 ? 403.616 387.599 299.033 1.00 95.12  ? 398 MET A CA    1 
ATOM   9721  C  C     . MET C 2 398 ? 405.124 387.431 299.191 1.00 94.25  ? 398 MET A C     1 
ATOM   9722  O  O     . MET C 2 398 ? 405.624 387.332 300.318 1.00 100.39 ? 398 MET A O     1 
ATOM   9723  C  CB    . MET C 2 398 ? 402.981 386.267 298.645 1.00 96.74  ? 398 MET A CB    1 
ATOM   9724  C  CG    . MET C 2 398 ? 401.491 386.203 298.878 1.00 98.32  ? 398 MET A CG    1 
ATOM   9725  S  SD    . MET C 2 398 ? 400.900 384.507 298.899 1.00 102.34 ? 398 MET A SD    1 
ATOM   9726  C  CE    . MET C 2 398 ? 400.659 384.235 297.158 1.00 94.70  ? 398 MET A CE    1 
ATOM   9727  N  N     . TYR C 2 399 ? 405.869 387.398 298.086 1.00 97.96  ? 399 TYR A N     1 
ATOM   9728  C  CA    . TYR C 2 399 ? 407.291 387.089 298.139 1.00 99.42  ? 399 TYR A CA    1 
ATOM   9729  C  C     . TYR C 2 399 ? 408.136 388.246 298.655 1.00 102.74 ? 399 TYR A C     1 
ATOM   9730  O  O     . TYR C 2 399 ? 409.276 388.017 299.074 1.00 104.42 ? 399 TYR A O     1 
ATOM   9731  C  CB    . TYR C 2 399 ? 407.780 386.680 296.746 1.00 103.51 ? 399 TYR A CB    1 
ATOM   9732  C  CG    . TYR C 2 399 ? 409.191 386.141 296.717 1.00 104.43 ? 399 TYR A CG    1 
ATOM   9733  C  CD1   . TYR C 2 399 ? 409.503 384.926 297.307 1.00 104.01 ? 399 TYR A CD1   1 
ATOM   9734  C  CD2   . TYR C 2 399 ? 410.212 386.855 296.110 1.00 104.52 ? 399 TYR A CD2   1 
ATOM   9735  C  CE1   . TYR C 2 399 ? 410.789 384.434 297.285 1.00 106.55 ? 399 TYR A CE1   1 
ATOM   9736  C  CE2   . TYR C 2 399 ? 411.502 386.371 296.084 1.00 105.52 ? 399 TYR A CE2   1 
ATOM   9737  C  CZ    . TYR C 2 399 ? 411.784 385.160 296.674 1.00 109.61 ? 399 TYR A CZ    1 
ATOM   9738  O  OH    . TYR C 2 399 ? 413.068 384.670 296.653 1.00 110.59 ? 399 TYR A OH    1 
ATOM   9739  N  N     . ALA C 2 400 ? 407.612 389.476 298.640 1.00 104.93 ? 400 ALA A N     1 
ATOM   9740  C  CA    . ALA C 2 400 ? 408.376 390.609 299.150 1.00 104.33 ? 400 ALA A CA    1 
ATOM   9741  C  C     . ALA C 2 400 ? 408.693 390.456 300.632 1.00 103.91 ? 400 ALA A C     1 
ATOM   9742  O  O     . ALA C 2 400 ? 409.732 390.941 301.093 1.00 106.22 ? 400 ALA A O     1 
ATOM   9743  C  CB    . ALA C 2 400 ? 407.611 391.908 298.905 1.00 99.18  ? 400 ALA A CB    1 
ATOM   9744  N  N     . LYS C 2 401 ? 407.818 389.783 301.383 1.00 94.47  ? 401 LYS A N     1 
ATOM   9745  C  CA    . LYS C 2 401 ? 408.006 389.510 302.803 1.00 93.35  ? 401 LYS A CA    1 
ATOM   9746  C  C     . LYS C 2 401 ? 408.293 388.040 303.098 1.00 92.68  ? 401 LYS A C     1 
ATOM   9747  O  O     . LYS C 2 401 ? 408.351 387.665 304.274 1.00 99.03  ? 401 LYS A O     1 
ATOM   9748  C  CB    . LYS C 2 401 ? 406.769 389.965 303.577 1.00 91.71  ? 401 LYS A CB    1 
ATOM   9749  C  CG    . LYS C 2 401 ? 406.522 391.461 303.494 1.00 95.69  ? 401 LYS A CG    1 
ATOM   9750  C  CD    . LYS C 2 401 ? 405.269 391.867 304.240 1.00 94.24  ? 401 LYS A CD    1 
ATOM   9751  C  CE    . LYS C 2 401 ? 405.148 393.378 304.345 1.00 97.79  ? 401 LYS A CE    1 
ATOM   9752  N  NZ    . LYS C 2 401 ? 405.172 394.053 303.017 1.00 97.02  ? 401 LYS A NZ    1 
ATOM   9753  N  N     . ARG C 2 402 ? 408.492 387.205 302.072 1.00 101.39 ? 402 ARG A N     1 
ATOM   9754  C  CA    . ARG C 2 402 ? 408.699 385.764 302.236 1.00 102.61 ? 402 ARG A CA    1 
ATOM   9755  C  C     . ARG C 2 402 ? 407.520 385.135 302.980 1.00 98.82  ? 402 ARG A C     1 
ATOM   9756  O  O     . ARG C 2 402 ? 407.658 384.580 304.071 1.00 103.55 ? 402 ARG A O     1 
ATOM   9757  C  CB    . ARG C 2 402 ? 410.024 385.469 302.954 1.00 102.12 ? 402 ARG A CB    1 
ATOM   9758  C  CG    . ARG C 2 402 ? 411.260 386.093 302.313 1.00 101.84 ? 402 ARG A CG    1 
ATOM   9759  C  CD    . ARG C 2 402 ? 411.540 385.503 300.943 1.00 108.09 ? 402 ARG A CD    1 
ATOM   9760  N  NE    . ARG C 2 402 ? 412.839 385.920 300.422 1.00 111.29 ? 402 ARG A NE    1 
ATOM   9761  C  CZ    . ARG C 2 402 ? 413.090 387.066 299.798 1.00 108.93 ? 402 ARG A CZ    1 
ATOM   9762  N  NH1   . ARG C 2 402 ? 412.151 387.982 299.602 1.00 103.50 ? 402 ARG A NH1   1 
ATOM   9763  N  NH2   . ARG C 2 402 ? 414.322 387.304 299.357 1.00 107.85 ? 402 ARG A NH2   1 
ATOM   9764  N  N     . ALA C 2 403 ? 406.343 385.242 302.357 1.00 91.60  ? 403 ALA A N     1 
ATOM   9765  C  CA    . ALA C 2 403 ? 405.098 384.923 303.047 1.00 89.79  ? 403 ALA A CA    1 
ATOM   9766  C  C     . ALA C 2 403 ? 405.003 383.445 303.402 1.00 91.47  ? 403 ALA A C     1 
ATOM   9767  O  O     . ALA C 2 403 ? 404.624 383.104 304.525 1.00 99.02  ? 403 ALA A O     1 
ATOM   9768  C  CB    . ALA C 2 403 ? 403.907 385.337 302.187 1.00 95.35  ? 403 ALA A CB    1 
ATOM   9769  N  N     . PHE C 2 404 ? 405.327 382.556 302.452 1.00 83.45  ? 404 PHE A N     1 
ATOM   9770  C  CA    . PHE C 2 404 ? 405.215 381.112 302.644 1.00 88.84  ? 404 PHE A CA    1 
ATOM   9771  C  C     . PHE C 2 404 ? 406.437 380.379 302.099 1.00 88.50  ? 404 PHE A C     1 
ATOM   9772  O  O     . PHE C 2 404 ? 406.349 379.186 301.787 1.00 86.10  ? 404 PHE A O     1 
ATOM   9773  C  CB    . PHE C 2 404 ? 403.942 380.568 301.969 1.00 90.21  ? 404 PHE A CB    1 
ATOM   9774  C  CG    . PHE C 2 404 ? 402.666 381.096 302.558 1.00 86.46  ? 404 PHE A CG    1 
ATOM   9775  C  CD1   . PHE C 2 404 ? 402.148 382.314 302.158 1.00 87.69  ? 404 PHE A CD1   1 
ATOM   9776  C  CD2   . PHE C 2 404 ? 401.975 380.359 303.500 1.00 86.05  ? 404 PHE A CD2   1 
ATOM   9777  C  CE1   . PHE C 2 404 ? 400.982 382.796 302.703 1.00 89.78  ? 404 PHE A CE1   1 
ATOM   9778  C  CE2   . PHE C 2 404 ? 400.804 380.837 304.047 1.00 87.80  ? 404 PHE A CE2   1 
ATOM   9779  C  CZ    . PHE C 2 404 ? 400.306 382.056 303.647 1.00 91.09  ? 404 PHE A CZ    1 
ATOM   9780  N  N     . VAL C 2 405 ? 407.579 381.059 301.993 1.00 90.16  ? 405 VAL A N     1 
ATOM   9781  C  CA    . VAL C 2 405 ? 408.730 380.477 301.315 1.00 92.51  ? 405 VAL A CA    1 
ATOM   9782  C  C     . VAL C 2 405 ? 409.334 379.334 302.125 1.00 95.98  ? 405 VAL A C     1 
ATOM   9783  O  O     . VAL C 2 405 ? 409.995 378.454 301.559 1.00 104.08 ? 405 VAL A O     1 
ATOM   9784  C  CB    . VAL C 2 405 ? 409.768 381.579 301.018 1.00 101.24 ? 405 VAL A CB    1 
ATOM   9785  C  CG1   . VAL C 2 405 ? 411.030 380.984 300.390 1.00 105.43 ? 405 VAL A CG1   1 
ATOM   9786  C  CG2   . VAL C 2 405 ? 409.163 382.655 300.108 1.00 102.23 ? 405 VAL A CG2   1 
ATOM   9787  N  N     . HIS C 2 406 ? 409.129 379.318 303.447 1.00 91.58  ? 406 HIS A N     1 
ATOM   9788  C  CA    . HIS C 2 406 ? 409.818 378.333 304.274 1.00 95.20  ? 406 HIS A CA    1 
ATOM   9789  C  C     . HIS C 2 406 ? 409.305 376.917 304.028 1.00 96.53  ? 406 HIS A C     1 
ATOM   9790  O  O     . HIS C 2 406 ? 410.081 375.963 304.136 1.00 98.57  ? 406 HIS A O     1 
ATOM   9791  C  CB    . HIS C 2 406 ? 409.709 378.717 305.754 1.00 96.31  ? 406 HIS A CB    1 
ATOM   9792  C  CG    . HIS C 2 406 ? 408.438 378.284 306.415 1.00 97.25  ? 406 HIS A CG    1 
ATOM   9793  N  ND1   . HIS C 2 406 ? 407.282 379.031 306.364 1.00 99.83  ? 406 HIS A ND1   1 
ATOM   9794  C  CD2   . HIS C 2 406 ? 408.147 377.190 307.158 1.00 91.43  ? 406 HIS A CD2   1 
ATOM   9795  C  CE1   . HIS C 2 406 ? 406.331 378.413 307.040 1.00 97.31  ? 406 HIS A CE1   1 
ATOM   9796  N  NE2   . HIS C 2 406 ? 406.829 377.292 307.530 1.00 95.50  ? 406 HIS A NE2   1 
ATOM   9797  N  N     . TRP C 2 407 ? 408.029 376.755 303.666 1.00 95.94  ? 407 TRP A N     1 
ATOM   9798  C  CA    . TRP C 2 407 ? 407.526 375.428 303.318 1.00 95.77  ? 407 TRP A CA    1 
ATOM   9799  C  C     . TRP C 2 407 ? 408.227 374.888 302.077 1.00 92.55  ? 407 TRP A C     1 
ATOM   9800  O  O     . TRP C 2 407 ? 408.686 373.735 302.054 1.00 90.49  ? 407 TRP A O     1 
ATOM   9801  C  CB    . TRP C 2 407 ? 406.016 375.487 303.082 1.00 87.06  ? 407 TRP A CB    1 
ATOM   9802  C  CG    . TRP C 2 407 ? 405.203 375.704 304.320 1.00 90.43  ? 407 TRP A CG    1 
ATOM   9803  C  CD1   . TRP C 2 407 ? 404.492 376.820 304.645 1.00 90.61  ? 407 TRP A CD1   1 
ATOM   9804  C  CD2   . TRP C 2 407 ? 405.004 374.775 305.391 1.00 94.68  ? 407 TRP A CD2   1 
ATOM   9805  N  NE1   . TRP C 2 407 ? 403.868 376.648 305.856 1.00 95.42  ? 407 TRP A NE1   1 
ATOM   9806  C  CE2   . TRP C 2 407 ? 404.167 375.400 306.334 1.00 93.01  ? 407 TRP A CE2   1 
ATOM   9807  C  CE3   . TRP C 2 407 ? 405.456 373.478 305.645 1.00 95.70  ? 407 TRP A CE3   1 
ATOM   9808  C  CZ2   . TRP C 2 407 ? 403.772 374.772 307.511 1.00 88.80  ? 407 TRP A CZ2   1 
ATOM   9809  C  CZ3   . TRP C 2 407 ? 405.064 372.857 306.814 1.00 95.04  ? 407 TRP A CZ3   1 
ATOM   9810  C  CH2   . TRP C 2 407 ? 404.230 373.503 307.733 1.00 91.46  ? 407 TRP A CH2   1 
ATOM   9811  N  N     . TYR C 2 408 ? 408.347 375.724 301.047 1.00 98.24  ? 408 TYR A N     1 
ATOM   9812  C  CA    . TYR C 2 408 ? 408.981 375.308 299.804 1.00 98.58  ? 408 TYR A CA    1 
ATOM   9813  C  C     . TYR C 2 408 ? 410.466 375.057 300.012 1.00 102.34 ? 408 TYR A C     1 
ATOM   9814  O  O     . TYR C 2 408 ? 411.041 374.155 299.394 1.00 107.73 ? 408 TYR A O     1 
ATOM   9815  C  CB    . TYR C 2 408 ? 408.770 376.370 298.722 1.00 103.20 ? 408 TYR A CB    1 
ATOM   9816  C  CG    . TYR C 2 408 ? 407.326 376.585 298.319 1.00 100.61 ? 408 TYR A CG    1 
ATOM   9817  C  CD1   . TYR C 2 408 ? 406.480 377.385 299.078 1.00 97.50  ? 408 TYR A CD1   1 
ATOM   9818  C  CD2   . TYR C 2 408 ? 406.811 375.998 297.175 1.00 100.01 ? 408 TYR A CD2   1 
ATOM   9819  C  CE1   . TYR C 2 408 ? 405.168 377.582 298.716 1.00 94.14  ? 408 TYR A CE1   1 
ATOM   9820  C  CE2   . TYR C 2 408 ? 405.498 376.193 296.808 1.00 97.28  ? 408 TYR A CE2   1 
ATOM   9821  C  CZ    . TYR C 2 408 ? 404.684 376.985 297.579 1.00 95.21  ? 408 TYR A CZ    1 
ATOM   9822  O  OH    . TYR C 2 408 ? 403.378 377.176 297.203 1.00 104.27 ? 408 TYR A OH    1 
ATOM   9823  N  N     . VAL C 2 409 ? 411.100 375.849 300.878 1.00 101.67 ? 409 VAL A N     1 
ATOM   9824  C  CA    . VAL C 2 409 ? 412.510 375.635 301.179 1.00 97.47  ? 409 VAL A CA    1 
ATOM   9825  C  C     . VAL C 2 409 ? 412.693 374.335 301.950 1.00 102.28 ? 409 VAL A C     1 
ATOM   9826  O  O     . VAL C 2 409 ? 413.675 373.611 301.746 1.00 102.76 ? 409 VAL A O     1 
ATOM   9827  C  CB    . VAL C 2 409 ? 413.083 376.846 301.939 1.00 103.14 ? 409 VAL A CB    1 
ATOM   9828  C  CG1   . VAL C 2 409 ? 414.467 376.537 302.503 1.00 108.00 ? 409 VAL A CG1   1 
ATOM   9829  C  CG2   . VAL C 2 409 ? 413.165 378.058 301.018 1.00 103.79 ? 409 VAL A CG2   1 
ATOM   9830  N  N     . GLY C 2 410 ? 411.761 374.022 302.851 1.00 107.10 ? 410 GLY A N     1 
ATOM   9831  C  CA    . GLY C 2 410 ? 411.829 372.759 303.559 1.00 109.06 ? 410 GLY A CA    1 
ATOM   9832  C  C     . GLY C 2 410 ? 411.670 371.566 302.642 1.00 108.03 ? 410 GLY A C     1 
ATOM   9833  O  O     . GLY C 2 410 ? 412.333 370.543 302.832 1.00 105.46 ? 410 GLY A O     1 
ATOM   9834  N  N     . GLU C 2 411 ? 410.807 371.680 301.633 1.00 120.58 ? 411 GLU A N     1 
ATOM   9835  C  CA    . GLU C 2 411 ? 410.582 370.595 300.685 1.00 121.01 ? 411 GLU A CA    1 
ATOM   9836  C  C     . GLU C 2 411 ? 411.588 370.581 299.530 1.00 118.52 ? 411 GLU A C     1 
ATOM   9837  O  O     . GLU C 2 411 ? 411.353 369.892 298.532 1.00 115.18 ? 411 GLU A O     1 
ATOM   9838  C  CB    . GLU C 2 411 ? 409.147 370.661 300.154 1.00 125.06 ? 411 GLU A CB    1 
ATOM   9839  C  CG    . GLU C 2 411 ? 408.102 370.320 301.211 1.00 129.33 ? 411 GLU A CG    1 
ATOM   9840  C  CD    . GLU C 2 411 ? 408.004 368.829 301.491 1.00 130.06 ? 411 GLU A CD    1 
ATOM   9841  O  OE1   . GLU C 2 411 ? 408.825 368.054 300.958 1.00 130.70 ? 411 GLU A OE1   1 
ATOM   9842  O  OE2   . GLU C 2 411 ? 407.118 368.432 302.274 1.00 128.42 ? 411 GLU A OE2   1 
ATOM   9843  N  N     . GLY C 2 412 ? 412.699 371.311 299.642 1.00 114.19 ? 412 GLY A N     1 
ATOM   9844  C  CA    . GLY C 2 412 ? 413.832 371.101 298.759 1.00 110.86 ? 412 GLY A CA    1 
ATOM   9845  C  C     . GLY C 2 412 ? 413.899 371.953 297.506 1.00 109.99 ? 412 GLY A C     1 
ATOM   9846  O  O     . GLY C 2 412 ? 414.003 371.416 296.399 1.00 108.29 ? 412 GLY A O     1 
ATOM   9847  N  N     . MET C 2 413 ? 413.840 373.275 297.655 1.00 108.12 ? 413 MET A N     1 
ATOM   9848  C  CA    . MET C 2 413 ? 414.151 374.180 296.556 1.00 108.63 ? 413 MET A CA    1 
ATOM   9849  C  C     . MET C 2 413 ? 414.620 375.512 297.125 1.00 116.13 ? 413 MET A C     1 
ATOM   9850  O  O     . MET C 2 413 ? 414.344 375.847 298.278 1.00 115.25 ? 413 MET A O     1 
ATOM   9851  C  CB    . MET C 2 413 ? 412.954 374.354 295.607 1.00 106.92 ? 413 MET A CB    1 
ATOM   9852  C  CG    . MET C 2 413 ? 411.684 374.965 296.209 1.00 107.47 ? 413 MET A CG    1 
ATOM   9853  S  SD    . MET C 2 413 ? 410.807 376.109 295.119 1.00 115.46 ? 413 MET A SD    1 
ATOM   9854  C  CE    . MET C 2 413 ? 410.804 375.239 293.552 1.00 114.03 ? 413 MET A CE    1 
ATOM   9855  N  N     . GLU C 2 414 ? 415.329 376.271 296.296 1.00 125.73 ? 414 GLU A N     1 
ATOM   9856  C  CA    . GLU C 2 414 ? 415.972 377.511 296.708 1.00 124.87 ? 414 GLU A CA    1 
ATOM   9857  C  C     . GLU C 2 414 ? 415.098 378.716 296.368 1.00 123.31 ? 414 GLU A C     1 
ATOM   9858  O  O     . GLU C 2 414 ? 414.129 378.627 295.613 1.00 125.97 ? 414 GLU A O     1 
ATOM   9859  C  CB    . GLU C 2 414 ? 417.344 377.649 296.038 1.00 127.01 ? 414 GLU A CB    1 
ATOM   9860  C  CG    . GLU C 2 414 ? 418.411 376.677 296.555 1.00 128.41 ? 414 GLU A CG    1 
ATOM   9861  C  CD    . GLU C 2 414 ? 418.277 375.262 296.007 1.00 126.06 ? 414 GLU A CD    1 
ATOM   9862  O  OE1   . GLU C 2 414 ? 417.577 375.061 294.992 1.00 121.69 ? 414 GLU A OE1   1 
ATOM   9863  O  OE2   . GLU C 2 414 ? 418.879 374.342 296.600 1.00 128.08 ? 414 GLU A OE2   1 
ATOM   9864  N  N     . GLU C 2 415 ? 415.460 379.862 296.951 1.00 122.09 ? 415 GLU A N     1 
ATOM   9865  C  CA    . GLU C 2 415 ? 414.844 381.129 296.569 1.00 126.79 ? 415 GLU A CA    1 
ATOM   9866  C  C     . GLU C 2 415 ? 415.234 381.555 295.158 1.00 127.27 ? 415 GLU A C     1 
ATOM   9867  O  O     . GLU C 2 415 ? 414.538 382.387 294.555 1.00 130.03 ? 415 GLU A O     1 
ATOM   9868  C  CB    . GLU C 2 415 ? 415.233 382.220 297.565 1.00 129.06 ? 415 GLU A CB    1 
ATOM   9869  C  CG    . GLU C 2 415 ? 414.422 382.199 298.848 1.00 127.71 ? 415 GLU A CG    1 
ATOM   9870  C  CD    . GLU C 2 415 ? 414.961 383.152 299.894 1.00 130.71 ? 415 GLU A CD    1 
ATOM   9871  O  OE1   . GLU C 2 415 ? 414.666 384.361 299.805 1.00 132.82 ? 415 GLU A OE1   1 
ATOM   9872  O  OE2   . GLU C 2 415 ? 415.677 382.691 300.808 1.00 127.84 ? 415 GLU A OE2   1 
ATOM   9873  N  N     . GLY C 2 416 ? 416.338 381.019 294.630 1.00 120.64 ? 416 GLY A N     1 
ATOM   9874  C  CA    . GLY C 2 416 ? 416.675 381.257 293.241 1.00 119.25 ? 416 GLY A CA    1 
ATOM   9875  C  C     . GLY C 2 416 ? 415.606 380.764 292.290 1.00 120.90 ? 416 GLY A C     1 
ATOM   9876  O  O     . GLY C 2 416 ? 415.383 381.369 291.242 1.00 123.48 ? 416 GLY A O     1 
ATOM   9877  N  N     . GLU C 2 417 ? 414.927 379.669 292.643 1.00 119.14 ? 417 GLU A N     1 
ATOM   9878  C  CA    . GLU C 2 417 ? 413.812 379.196 291.829 1.00 118.68 ? 417 GLU A CA    1 
ATOM   9879  C  C     . GLU C 2 417 ? 412.690 380.226 291.782 1.00 121.58 ? 417 GLU A C     1 
ATOM   9880  O  O     . GLU C 2 417 ? 412.137 380.499 290.710 1.00 127.72 ? 417 GLU A O     1 
ATOM   9881  C  CB    . GLU C 2 417 ? 413.288 377.868 292.374 1.00 120.80 ? 417 GLU A CB    1 
ATOM   9882  C  CG    . GLU C 2 417 ? 414.116 376.659 291.979 1.00 124.87 ? 417 GLU A CG    1 
ATOM   9883  C  CD    . GLU C 2 417 ? 413.442 375.820 290.913 1.00 127.07 ? 417 GLU A CD    1 
ATOM   9884  O  OE1   . GLU C 2 417 ? 413.155 376.359 289.824 1.00 127.25 ? 417 GLU A OE1   1 
ATOM   9885  O  OE2   . GLU C 2 417 ? 413.198 374.622 291.165 1.00 129.28 ? 417 GLU A OE2   1 
ATOM   9886  N  N     . PHE C 2 418 ? 412.349 380.814 292.932 1.00 103.67 ? 418 PHE A N     1 
ATOM   9887  C  CA    . PHE C 2 418 ? 411.306 381.835 292.973 1.00 103.67 ? 418 PHE A CA    1 
ATOM   9888  C  C     . PHE C 2 418 ? 411.699 383.050 292.145 1.00 103.90 ? 418 PHE A C     1 
ATOM   9889  O  O     . PHE C 2 418 ? 410.898 383.567 291.354 1.00 107.73 ? 418 PHE A O     1 
ATOM   9890  C  CB    . PHE C 2 418 ? 411.042 382.251 294.420 1.00 101.76 ? 418 PHE A CB    1 
ATOM   9891  C  CG    . PHE C 2 418 ? 410.219 381.270 295.197 1.00 104.25 ? 418 PHE A CG    1 
ATOM   9892  C  CD1   . PHE C 2 418 ? 410.787 380.115 295.700 1.00 107.12 ? 418 PHE A CD1   1 
ATOM   9893  C  CD2   . PHE C 2 418 ? 408.880 381.513 295.442 1.00 103.12 ? 418 PHE A CD2   1 
ATOM   9894  C  CE1   . PHE C 2 418 ? 410.031 379.217 296.420 1.00 108.42 ? 418 PHE A CE1   1 
ATOM   9895  C  CE2   . PHE C 2 418 ? 408.122 380.619 296.161 1.00 103.84 ? 418 PHE A CE2   1 
ATOM   9896  C  CZ    . PHE C 2 418 ? 408.697 379.470 296.650 1.00 106.58 ? 418 PHE A CZ    1 
ATOM   9897  N  N     . SER C 2 419 ? 412.940 383.512 292.310 1.00 105.55 ? 419 SER A N     1 
ATOM   9898  C  CA    . SER C 2 419 ? 413.394 384.689 291.573 1.00 103.96 ? 419 SER A CA    1 
ATOM   9899  C  C     . SER C 2 419 ? 413.426 384.424 290.072 1.00 109.08 ? 419 SER A C     1 
ATOM   9900  O  O     . SER C 2 419 ? 413.005 385.271 289.274 1.00 106.11 ? 419 SER A O     1 
ATOM   9901  C  CB    . SER C 2 419 ? 414.774 385.113 292.070 1.00 106.87 ? 419 SER A CB    1 
ATOM   9902  O  OG    . SER C 2 419 ? 415.769 384.205 291.635 1.00 113.46 ? 419 SER A OG    1 
ATOM   9903  N  N     . GLU C 2 420 ? 413.909 383.247 289.669 1.00 115.52 ? 420 GLU A N     1 
ATOM   9904  C  CA    . GLU C 2 420 ? 413.976 382.909 288.253 1.00 114.47 ? 420 GLU A CA    1 
ATOM   9905  C  C     . GLU C 2 420 ? 412.586 382.773 287.650 1.00 119.24 ? 420 GLU A C     1 
ATOM   9906  O  O     . GLU C 2 420 ? 412.356 383.201 286.514 1.00 123.91 ? 420 GLU A O     1 
ATOM   9907  C  CB    . GLU C 2 420 ? 414.770 381.618 288.068 1.00 112.83 ? 420 GLU A CB    1 
ATOM   9908  C  CG    . GLU C 2 420 ? 416.259 381.773 288.320 1.00 114.53 ? 420 GLU A CG    1 
ATOM   9909  C  CD    . GLU C 2 420 ? 416.938 380.452 288.612 1.00 121.88 ? 420 GLU A CD    1 
ATOM   9910  O  OE1   . GLU C 2 420 ? 416.557 379.437 287.992 1.00 121.34 ? 420 GLU A OE1   1 
ATOM   9911  O  OE2   . GLU C 2 420 ? 417.851 380.427 289.463 1.00 123.21 ? 420 GLU A OE2   1 
ATOM   9912  N  N     . ALA C 2 421 ? 411.646 382.174 288.388 1.00 110.58 ? 421 ALA A N     1 
ATOM   9913  C  CA    . ALA C 2 421 ? 410.282 382.059 287.886 1.00 110.12 ? 421 ALA A CA    1 
ATOM   9914  C  C     . ALA C 2 421 ? 409.639 383.429 287.727 1.00 111.97 ? 421 ALA A C     1 
ATOM   9915  O  O     . ALA C 2 421 ? 408.938 383.684 286.738 1.00 113.20 ? 421 ALA A O     1 
ATOM   9916  C  CB    . ALA C 2 421 ? 409.452 381.181 288.821 1.00 107.78 ? 421 ALA A CB    1 
ATOM   9917  N  N     . ARG C 2 422 ? 409.871 384.327 288.688 1.00 108.58 ? 422 ARG A N     1 
ATOM   9918  C  CA    . ARG C 2 422 ? 409.332 385.677 288.569 1.00 106.76 ? 422 ARG A CA    1 
ATOM   9919  C  C     . ARG C 2 422 ? 409.934 386.402 287.372 1.00 108.09 ? 422 ARG A C     1 
ATOM   9920  O  O     . ARG C 2 422 ? 409.224 387.100 286.638 1.00 109.74 ? 422 ARG A O     1 
ATOM   9921  C  CB    . ARG C 2 422 ? 409.589 386.461 289.858 1.00 106.04 ? 422 ARG A CB    1 
ATOM   9922  C  CG    . ARG C 2 422 ? 409.090 387.917 289.874 1.00 106.99 ? 422 ARG A CG    1 
ATOM   9923  C  CD    . ARG C 2 422 ? 407.589 388.050 289.631 1.00 107.07 ? 422 ARG A CD    1 
ATOM   9924  N  NE    . ARG C 2 422 ? 407.168 389.449 289.647 1.00 110.63 ? 422 ARG A NE    1 
ATOM   9925  C  CZ    . ARG C 2 422 ? 406.922 390.211 288.585 1.00 110.65 ? 422 ARG A CZ    1 
ATOM   9926  N  NH1   . ARG C 2 422 ? 407.086 389.774 287.344 1.00 110.11 ? 422 ARG A NH1   1 
ATOM   9927  N  NH2   . ARG C 2 422 ? 406.502 391.459 288.772 1.00 108.87 ? 422 ARG A NH2   1 
ATOM   9928  N  N     . GLU C 2 423 ? 411.243 386.247 287.159 1.00 105.68 ? 423 GLU A N     1 
ATOM   9929  C  CA    . GLU C 2 423 ? 411.886 386.887 286.016 1.00 105.02 ? 423 GLU A CA    1 
ATOM   9930  C  C     . GLU C 2 423 ? 411.353 386.330 284.702 1.00 108.62 ? 423 GLU A C     1 
ATOM   9931  O  O     . GLU C 2 423 ? 411.140 387.079 283.742 1.00 112.89 ? 423 GLU A O     1 
ATOM   9932  C  CB    . GLU C 2 423 ? 413.399 386.699 286.103 1.00 106.80 ? 423 GLU A CB    1 
ATOM   9933  C  CG    . GLU C 2 423 ? 414.062 387.558 287.164 1.00 113.90 ? 423 GLU A CG    1 
ATOM   9934  C  CD    . GLU C 2 423 ? 415.516 387.196 287.381 1.00 117.00 ? 423 GLU A CD    1 
ATOM   9935  O  OE1   . GLU C 2 423 ? 416.111 386.560 286.487 1.00 116.82 ? 423 GLU A OE1   1 
ATOM   9936  O  OE2   . GLU C 2 423 ? 416.064 387.546 288.448 1.00 113.88 ? 423 GLU A OE2   1 
ATOM   9937  N  N     . ASP C 2 424 ? 411.129 385.017 284.643 1.00 112.79 ? 424 ASP A N     1 
ATOM   9938  C  CA    . ASP C 2 424 ? 410.595 384.408 283.431 1.00 115.16 ? 424 ASP A CA    1 
ATOM   9939  C  C     . ASP C 2 424 ? 409.182 384.895 283.142 1.00 114.42 ? 424 ASP A C     1 
ATOM   9940  O  O     . ASP C 2 424 ? 408.841 385.173 281.987 1.00 120.36 ? 424 ASP A O     1 
ATOM   9941  C  CB    . ASP C 2 424 ? 410.622 382.886 283.560 1.00 115.64 ? 424 ASP A CB    1 
ATOM   9942  C  CG    . ASP C 2 424 ? 410.228 382.188 282.277 1.00 120.24 ? 424 ASP A CG    1 
ATOM   9943  O  OD1   . ASP C 2 424 ? 410.906 382.401 281.251 1.00 121.84 ? 424 ASP A OD1   1 
ATOM   9944  O  OD2   . ASP C 2 424 ? 409.244 381.419 282.295 1.00 121.84 ? 424 ASP A OD2   1 
ATOM   9945  N  N     . MET C 2 425 ? 408.344 385.011 284.174 1.00 108.82 ? 425 MET A N     1 
ATOM   9946  C  CA    . MET C 2 425 ? 406.993 385.521 283.950 1.00 114.21 ? 425 MET A CA    1 
ATOM   9947  C  C     . MET C 2 425 ? 407.012 386.998 283.567 1.00 112.66 ? 425 MET A C     1 
ATOM   9948  O  O     . MET C 2 425 ? 406.174 387.443 282.772 1.00 112.99 ? 425 MET A O     1 
ATOM   9949  C  CB    . MET C 2 425 ? 406.126 385.304 285.195 1.00 110.52 ? 425 MET A CB    1 
ATOM   9950  C  CG    . MET C 2 425 ? 404.668 384.901 284.926 1.00 108.55 ? 425 MET A CG    1 
ATOM   9951  S  SD    . MET C 2 425 ? 404.309 383.447 283.895 1.00 129.89 ? 425 MET A SD    1 
ATOM   9952  C  CE    . MET C 2 425 ? 405.789 382.437 284.031 1.00 116.84 ? 425 MET A CE    1 
ATOM   9953  N  N     . ALA C 2 426 ? 407.960 387.769 284.105 1.00 103.26 ? 426 ALA A N     1 
ATOM   9954  C  CA    . ALA C 2 426 ? 408.127 389.147 283.656 1.00 100.37 ? 426 ALA A CA    1 
ATOM   9955  C  C     . ALA C 2 426 ? 408.508 389.197 282.184 1.00 103.61 ? 426 ALA A C     1 
ATOM   9956  O  O     . ALA C 2 426 ? 407.993 390.028 281.428 1.00 108.67 ? 426 ALA A O     1 
ATOM   9957  C  CB    . ALA C 2 426 ? 409.186 389.853 284.500 1.00 99.28  ? 426 ALA A CB    1 
ATOM   9958  N  N     . ALA C 2 427 ? 409.411 388.310 281.763 1.00 105.59 ? 427 ALA A N     1 
ATOM   9959  C  CA    . ALA C 2 427 ? 409.774 388.231 280.352 1.00 105.50 ? 427 ALA A CA    1 
ATOM   9960  C  C     . ALA C 2 427 ? 408.574 387.845 279.500 1.00 109.59 ? 427 ALA A C     1 
ATOM   9961  O  O     . ALA C 2 427 ? 408.420 388.332 278.376 1.00 114.71 ? 427 ALA A O     1 
ATOM   9962  C  CB    . ALA C 2 427 ? 410.909 387.227 280.160 1.00 102.64 ? 427 ALA A CB    1 
ATOM   9963  N  N     . LEU C 2 428 ? 407.728 386.957 280.031 1.00 109.33 ? 428 LEU A N     1 
ATOM   9964  C  CA    . LEU C 2 428 ? 406.511 386.530 279.289 1.00 109.16 ? 428 LEU A CA    1 
ATOM   9965  C  C     . LEU C 2 428 ? 405.589 387.739 279.111 1.00 110.43 ? 428 LEU A C     1 
ATOM   9966  O  O     . LEU C 2 428 ? 405.142 387.981 277.972 1.00 114.72 ? 428 LEU A O     1 
ATOM   9967  C  CB    . LEU C 2 428 ? 405.805 385.417 280.067 1.00 105.87 ? 428 LEU A CB    1 
ATOM   9968  C  CG    . LEU C 2 428 ? 404.436 385.016 279.517 1.00 107.12 ? 428 LEU A CG    1 
ATOM   9969  C  CD1   . LEU C 2 428 ? 404.582 384.237 278.221 1.00 112.61 ? 428 LEU A CD1   1 
ATOM   9970  C  CD2   . LEU C 2 428 ? 403.649 384.211 280.538 1.00 110.34 ? 428 LEU A CD2   1 
ATOM   9971  N  N     . GLU C 2 429 ? 405.324 388.468 280.198 1.00 115.57 ? 429 GLU A N     1 
ATOM   9972  C  CA    . GLU C 2 429 ? 404.437 389.659 280.131 1.00 111.74 ? 429 GLU A CA    1 
ATOM   9973  C  C     . GLU C 2 429 ? 405.027 390.658 279.130 1.00 113.47 ? 429 GLU A C     1 
ATOM   9974  O  O     . GLU C 2 429 ? 404.252 391.219 278.329 1.00 117.99 ? 429 GLU A O     1 
ATOM   9975  C  CB    . GLU C 2 429 ? 404.287 390.278 281.522 1.00 113.83 ? 429 GLU A CB    1 
ATOM   9976  C  CG    . GLU C 2 429 ? 403.380 391.494 281.551 1.00 118.48 ? 429 GLU A CG    1 
ATOM   9977  C  CD    . GLU C 2 429 ? 403.096 392.033 282.943 1.00 127.38 ? 429 GLU A CD    1 
ATOM   9978  O  OE1   . GLU C 2 429 ? 403.593 391.436 283.919 1.00 128.20 ? 429 GLU A OE1   1 
ATOM   9979  O  OE2   . GLU C 2 429 ? 402.382 393.049 283.046 1.00 128.05 ? 429 GLU A OE2   1 
ATOM   9980  N  N     . LYS C 2 430 ? 406.347 390.857 279.170 1.00 114.29 ? 430 LYS A N     1 
ATOM   9981  C  CA    . LYS C 2 430 ? 407.014 391.773 278.206 1.00 115.24 ? 430 LYS A CA    1 
ATOM   9982  C  C     . LYS C 2 430 ? 406.738 391.283 276.781 1.00 118.86 ? 430 LYS A C     1 
ATOM   9983  O  O     . LYS C 2 430 ? 406.260 392.089 275.964 1.00 118.48 ? 430 LYS A O     1 
ATOM   9984  C  CB    . LYS C 2 430 ? 408.518 391.849 278.489 1.00 115.70 ? 430 LYS A CB    1 
ATOM   9985  C  CG    . LYS C 2 430 ? 409.298 392.815 277.607 1.00 120.25 ? 430 LYS A CG    1 
ATOM   9986  C  CD    . LYS C 2 430 ? 410.769 392.895 277.951 1.00 126.32 ? 430 LYS A CD    1 
ATOM   9987  C  CE    . LYS C 2 430 ? 411.543 393.839 277.055 1.00 124.42 ? 430 LYS A CE    1 
ATOM   9988  N  NZ    . LYS C 2 430 ? 412.977 393.889 277.424 1.00 121.90 ? 430 LYS A NZ    1 
ATOM   9989  N  N     . ASP C 2 431 ? 407.026 390.008 276.503 1.00 121.25 ? 431 ASP A N     1 
ATOM   9990  C  CA    . ASP C 2 431 ? 406.773 389.458 275.174 1.00 118.94 ? 431 ASP A CA    1 
ATOM   9991  C  C     . ASP C 2 431 ? 405.341 389.727 274.732 1.00 114.39 ? 431 ASP A C     1 
ATOM   9992  O  O     . ASP C 2 431 ? 405.095 390.062 273.566 1.00 119.35 ? 431 ASP A O     1 
ATOM   9993  C  CB    . ASP C 2 431 ? 407.057 387.956 275.161 1.00 121.60 ? 431 ASP A CB    1 
ATOM   9994  C  CG    . ASP C 2 431 ? 408.509 387.636 275.443 1.00 124.59 ? 431 ASP A CG    1 
ATOM   9995  O  OD1   . ASP C 2 431 ? 409.326 388.576 275.514 1.00 124.73 ? 431 ASP A OD1   1 
ATOM   9996  O  OD2   . ASP C 2 431 ? 408.834 386.440 275.600 1.00 122.33 ? 431 ASP A OD2   1 
ATOM   9997  N  N     . TYR C 2 432 ? 404.383 389.583 275.650 1.00 105.29 ? 432 TYR A N     1 
ATOM   9998  C  CA    . TYR C 2 432 ? 402.983 389.815 275.297 1.00 106.86 ? 432 TYR A CA    1 
ATOM   9999  C  C     . TYR C 2 432 ? 402.739 391.276 274.936 1.00 106.48 ? 432 TYR A C     1 
ATOM   10000 O  O     . TYR C 2 432 ? 402.096 391.579 273.922 1.00 107.85 ? 432 TYR A O     1 
ATOM   10001 C  CB    . TYR C 2 432 ? 402.058 389.384 276.438 1.00 106.95 ? 432 TYR A CB    1 
ATOM   10002 C  CG    . TYR C 2 432 ? 401.350 388.082 276.160 1.00 105.39 ? 432 TYR A CG    1 
ATOM   10003 C  CD1   . TYR C 2 432 ? 400.089 388.066 275.586 1.00 105.92 ? 432 TYR A CD1   1 
ATOM   10004 C  CD2   . TYR C 2 432 ? 401.947 386.868 276.464 1.00 107.22 ? 432 TYR A CD2   1 
ATOM   10005 C  CE1   . TYR C 2 432 ? 399.439 386.879 275.326 1.00 107.64 ? 432 TYR A CE1   1 
ATOM   10006 C  CE2   . TYR C 2 432 ? 401.305 385.677 276.207 1.00 109.32 ? 432 TYR A CE2   1 
ATOM   10007 C  CZ    . TYR C 2 432 ? 400.052 385.687 275.635 1.00 109.85 ? 432 TYR A CZ    1 
ATOM   10008 O  OH    . TYR C 2 432 ? 399.406 384.501 275.382 1.00 111.39 ? 432 TYR A OH    1 
ATOM   10009 N  N     . GLU C 2 433 ? 403.256 392.203 275.746 1.00 120.36 ? 433 GLU A N     1 
ATOM   10010 C  CA    . GLU C 2 433 ? 403.061 393.612 275.423 1.00 118.64 ? 433 GLU A CA    1 
ATOM   10011 C  C     . GLU C 2 433 ? 403.852 394.010 274.182 1.00 118.17 ? 433 GLU A C     1 
ATOM   10012 O  O     . GLU C 2 433 ? 403.452 394.937 273.472 1.00 117.55 ? 433 GLU A O     1 
ATOM   10013 C  CB    . GLU C 2 433 ? 403.425 394.498 276.621 1.00 121.11 ? 433 GLU A CB    1 
ATOM   10014 C  CG    . GLU C 2 433 ? 404.899 394.858 276.777 1.00 125.25 ? 433 GLU A CG    1 
ATOM   10015 C  CD    . GLU C 2 433 ? 405.208 395.446 278.140 1.00 127.99 ? 433 GLU A CD    1 
ATOM   10016 O  OE1   . GLU C 2 433 ? 404.368 396.210 278.661 1.00 127.52 ? 433 GLU A OE1   1 
ATOM   10017 O  OE2   . GLU C 2 433 ? 406.290 395.151 278.688 1.00 124.08 ? 433 GLU A OE2   1 
ATOM   10018 N  N     . GLU C 2 434 ? 404.966 393.327 273.903 1.00 115.89 ? 434 GLU A N     1 
ATOM   10019 C  CA    . GLU C 2 434 ? 405.727 393.596 272.688 1.00 115.82 ? 434 GLU A CA    1 
ATOM   10020 C  C     . GLU C 2 434 ? 404.945 393.184 271.448 1.00 118.89 ? 434 GLU A C     1 
ATOM   10021 O  O     . GLU C 2 434 ? 404.801 393.970 270.504 1.00 119.47 ? 434 GLU A O     1 
ATOM   10022 C  CB    . GLU C 2 434 ? 407.071 392.865 272.757 1.00 113.42 ? 434 GLU A CB    1 
ATOM   10023 C  CG    . GLU C 2 434 ? 407.820 392.738 271.430 1.00 117.35 ? 434 GLU A CG    1 
ATOM   10024 C  CD    . GLU C 2 434 ? 409.276 392.347 271.612 1.00 119.50 ? 434 GLU A CD    1 
ATOM   10025 O  OE1   . GLU C 2 434 ? 409.947 392.907 272.505 1.00 116.52 ? 434 GLU A OE1   1 
ATOM   10026 O  OE2   . GLU C 2 434 ? 409.752 391.473 270.859 1.00 116.99 ? 434 GLU A OE2   1 
ATOM   10027 N  N     . VAL C 2 435 ? 404.428 391.952 271.429 1.00 114.06 ? 435 VAL A N     1 
ATOM   10028 C  CA    . VAL C 2 435 ? 403.663 391.504 270.269 1.00 105.35 ? 435 VAL A CA    1 
ATOM   10029 C  C     . VAL C 2 435 ? 402.332 392.237 270.166 1.00 103.04 ? 435 VAL A C     1 
ATOM   10030 O  O     . VAL C 2 435 ? 401.734 392.269 269.085 1.00 102.55 ? 435 VAL A O     1 
ATOM   10031 C  CB    . VAL C 2 435 ? 403.441 389.975 270.278 1.00 102.75 ? 435 VAL A CB    1 
ATOM   10032 C  CG1   . VAL C 2 435 ? 404.777 389.239 270.257 1.00 102.01 ? 435 VAL A CG1   1 
ATOM   10033 C  CG2   . VAL C 2 435 ? 402.583 389.517 271.457 1.00 106.91 ? 435 VAL A CG2   1 
ATOM   10034 N  N     . GLY C 2 436 ? 401.847 392.832 271.258 1.00 109.59 ? 436 GLY A N     1 
ATOM   10035 C  CA    . GLY C 2 436 ? 400.686 393.700 271.163 1.00 109.57 ? 436 GLY A CA    1 
ATOM   10036 C  C     . GLY C 2 436 ? 400.939 395.024 270.464 1.00 108.49 ? 436 GLY A C     1 
ATOM   10037 O  O     . GLY C 2 436 ? 399.971 395.719 270.137 1.00 101.48 ? 436 GLY A O     1 
ATOM   10038 N  N     . VAL C 2 437 ? 402.202 395.391 270.228 1.00 124.96 ? 437 VAL A N     1 
ATOM   10039 C  CA    . VAL C 2 437 ? 402.504 396.652 269.560 1.00 124.76 ? 437 VAL A CA    1 
ATOM   10040 C  C     . VAL C 2 437 ? 402.092 396.570 268.098 1.00 122.10 ? 437 VAL A C     1 
ATOM   10041 O  O     . VAL C 2 437 ? 402.321 395.559 267.420 1.00 118.62 ? 437 VAL A O     1 
ATOM   10042 C  CB    . VAL C 2 437 ? 403.999 396.994 269.688 1.00 125.21 ? 437 VAL A CB    1 
ATOM   10043 C  CG1   . VAL C 2 437 ? 404.325 398.265 268.895 1.00 124.19 ? 437 VAL A CG1   1 
ATOM   10044 C  CG2   . VAL C 2 437 ? 404.393 397.141 271.154 1.00 121.87 ? 437 VAL A CG2   1 
ATOM   10045 N  N     . ASP C 2 438 ? 401.479 397.641 267.603 1.00 115.71 ? 438 ASP A N     1 
ATOM   10046 C  CA    . ASP C 2 438 ? 401.144 397.725 266.191 1.00 115.81 ? 438 ASP A CA    1 
ATOM   10047 C  C     . ASP C 2 438 ? 402.405 397.916 265.356 1.00 115.38 ? 438 ASP A C     1 
ATOM   10048 O  O     . ASP C 2 438 ? 403.359 398.580 265.770 1.00 110.05 ? 438 ASP A O     1 
ATOM   10049 C  CB    . ASP C 2 438 ? 400.172 398.878 265.940 1.00 110.20 ? 438 ASP A CB    1 
ATOM   10050 N  N     . SER C 2 439 ? 402.402 397.323 264.166 1.00 127.13 ? 439 SER A N     1 
ATOM   10051 C  CA    . SER C 2 439 ? 403.548 397.427 263.276 1.00 125.03 ? 439 SER A CA    1 
ATOM   10052 C  C     . SER C 2 439 ? 403.705 398.855 262.766 1.00 127.08 ? 439 SER A C     1 
ATOM   10053 O  O     . SER C 2 439 ? 402.726 399.582 262.574 1.00 127.39 ? 439 SER A O     1 
ATOM   10054 C  CB    . SER C 2 439 ? 403.397 396.466 262.098 1.00 119.65 ? 439 SER A CB    1 
ATOM   10055 N  N     . VAL C 2 440 ? 404.960 399.251 262.556 1.00 138.62 ? 440 VAL A N     1 
ATOM   10056 C  CA    . VAL C 2 440 ? 405.319 400.573 262.057 1.00 139.55 ? 440 VAL A CA    1 
ATOM   10057 C  C     . VAL C 2 440 ? 406.339 400.405 260.941 1.00 141.80 ? 440 VAL A C     1 
ATOM   10058 O  O     . VAL C 2 440 ? 407.275 399.607 261.060 1.00 138.49 ? 440 VAL A O     1 
ATOM   10059 C  CB    . VAL C 2 440 ? 405.884 401.472 263.176 1.00 135.46 ? 440 VAL A CB    1 
ATOM   10060 N  N     . GLU C 2 441 ? 406.152 401.157 259.859 1.00 141.51 ? 441 GLU A N     1 
ATOM   10061 C  CA    . GLU C 2 441 ? 407.037 401.104 258.697 1.00 137.94 ? 441 GLU A CA    1 
ATOM   10062 C  C     . GLU C 2 441 ? 407.043 399.712 258.073 1.00 137.00 ? 441 GLU A C     1 
ATOM   10063 O  O     . GLU C 2 441 ? 406.000 399.202 257.662 1.00 131.71 ? 441 GLU A O     1 
ATOM   10064 C  CB    . GLU C 2 441 ? 408.461 401.513 259.084 1.00 131.63 ? 441 GLU A CB    1 
ATOM   10065 N  N     . MET D 2 1   ? 394.496 354.947 183.552 1.00 144.62 ? 1   MET D N     1 
ATOM   10066 C  CA    . MET D 2 1   ? 395.166 355.765 182.501 1.00 145.22 ? 1   MET D CA    1 
ATOM   10067 C  C     . MET D 2 1   ? 395.727 357.045 183.108 1.00 146.28 ? 1   MET D C     1 
ATOM   10068 O  O     . MET D 2 1   ? 396.873 357.413 182.851 1.00 146.49 ? 1   MET D O     1 
ATOM   10069 C  CB    . MET D 2 1   ? 394.180 356.097 181.373 1.00 147.34 ? 1   MET D CB    1 
ATOM   10070 C  CG    . MET D 2 1   ? 394.814 356.374 180.007 1.00 149.04 ? 1   MET D CG    1 
ATOM   10071 S  SD    . MET D 2 1   ? 395.067 358.132 179.689 1.00 158.32 ? 1   MET D SD    1 
ATOM   10072 C  CE    . MET D 2 1   ? 393.892 358.415 178.365 1.00 141.01 ? 1   MET D CE    1 
ATOM   10073 N  N     . ARG D 2 2   ? 394.901 357.715 183.909 1.00 129.68 ? 2   ARG D N     1 
ATOM   10074 C  CA    . ARG D 2 2   ? 395.281 358.929 184.622 1.00 125.58 ? 2   ARG D CA    1 
ATOM   10075 C  C     . ARG D 2 2   ? 394.739 358.833 186.038 1.00 125.01 ? 2   ARG D C     1 
ATOM   10076 O  O     . ARG D 2 2   ? 393.553 358.547 186.226 1.00 124.89 ? 2   ARG D O     1 
ATOM   10077 C  CB    . ARG D 2 2   ? 394.752 360.187 183.918 1.00 124.76 ? 2   ARG D CB    1 
ATOM   10078 C  CG    . ARG D 2 2   ? 393.235 360.251 183.729 1.00 125.38 ? 2   ARG D CG    1 
ATOM   10079 C  CD    . ARG D 2 2   ? 392.858 361.071 182.501 1.00 122.15 ? 2   ARG D CD    1 
ATOM   10080 N  NE    . ARG D 2 2   ? 391.419 361.070 182.264 1.00 127.96 ? 2   ARG D NE    1 
ATOM   10081 C  CZ    . ARG D 2 2   ? 390.718 360.049 181.783 1.00 131.16 ? 2   ARG D CZ    1 
ATOM   10082 N  NH1   . ARG D 2 2   ? 391.288 358.896 181.462 1.00 127.37 ? 2   ARG D NH1   1 
ATOM   10083 N  NH2   . ARG D 2 2   ? 389.406 360.186 181.621 1.00 133.38 ? 2   ARG D NH2   1 
ATOM   10084 N  N     . GLU D 2 3   ? 395.606 359.073 187.022 1.00 119.48 ? 3   GLU D N     1 
ATOM   10085 C  CA    . GLU D 2 3   ? 395.319 358.798 188.423 1.00 113.97 ? 3   GLU D CA    1 
ATOM   10086 C  C     . GLU D 2 3   ? 395.732 359.980 189.288 1.00 114.74 ? 3   GLU D C     1 
ATOM   10087 O  O     . GLU D 2 3   ? 396.577 360.793 188.907 1.00 122.47 ? 3   GLU D O     1 
ATOM   10088 C  CB    . GLU D 2 3   ? 396.051 357.538 188.904 1.00 118.01 ? 3   GLU D CB    1 
ATOM   10089 C  CG    . GLU D 2 3   ? 395.513 356.239 188.329 1.00 123.11 ? 3   GLU D CG    1 
ATOM   10090 C  CD    . GLU D 2 3   ? 396.157 355.879 187.004 1.00 125.73 ? 3   GLU D CD    1 
ATOM   10091 O  OE1   . GLU D 2 3   ? 397.367 355.565 186.997 1.00 128.21 ? 3   GLU D OE1   1 
ATOM   10092 O  OE2   . GLU D 2 3   ? 395.455 355.904 185.972 1.00 123.93 ? 3   GLU D OE2   1 
ATOM   10093 N  N     . CYS D 2 4   ? 395.112 360.059 190.465 1.00 111.77 ? 4   CYS D N     1 
ATOM   10094 C  CA    . CYS D 2 4   ? 395.429 361.060 191.472 1.00 117.47 ? 4   CYS D CA    1 
ATOM   10095 C  C     . CYS D 2 4   ? 395.417 360.401 192.842 1.00 117.39 ? 4   CYS D C     1 
ATOM   10096 O  O     . CYS D 2 4   ? 394.716 359.410 193.060 1.00 121.08 ? 4   CYS D O     1 
ATOM   10097 C  CB    . CYS D 2 4   ? 394.432 362.225 191.449 1.00 113.46 ? 4   CYS D CB    1 
ATOM   10098 S  SG    . CYS D 2 4   ? 394.559 363.283 189.996 1.00 127.41 ? 4   CYS D SG    1 
ATOM   10099 N  N     . ILE D 2 5   ? 396.199 360.967 193.760 1.00 105.79 ? 5   ILE D N     1 
ATOM   10100 C  CA    . ILE D 2 5   ? 396.301 360.498 195.139 1.00 98.91  ? 5   ILE D CA    1 
ATOM   10101 C  C     . ILE D 2 5   ? 395.886 361.643 196.049 1.00 104.16 ? 5   ILE D C     1 
ATOM   10102 O  O     . ILE D 2 5   ? 396.443 362.743 195.960 1.00 111.78 ? 5   ILE D O     1 
ATOM   10103 C  CB    . ILE D 2 5   ? 397.725 360.012 195.475 1.00 99.20  ? 5   ILE D CB    1 
ATOM   10104 C  CG1   . ILE D 2 5   ? 398.053 358.725 194.711 1.00 96.43  ? 5   ILE D CG1   1 
ATOM   10105 C  CG2   . ILE D 2 5   ? 397.875 359.763 196.974 1.00 105.80 ? 5   ILE D CG2   1 
ATOM   10106 C  CD1   . ILE D 2 5   ? 399.533 358.503 194.493 1.00 104.32 ? 5   ILE D CD1   1 
ATOM   10107 N  N     . SER D 2 6   ? 394.916 361.379 196.923 1.00 103.57 ? 6   SER D N     1 
ATOM   10108 C  CA    . SER D 2 6   ? 394.370 362.365 197.849 1.00 101.53 ? 6   SER D CA    1 
ATOM   10109 C  C     . SER D 2 6   ? 394.894 362.068 199.246 1.00 101.99 ? 6   SER D C     1 
ATOM   10110 O  O     . SER D 2 6   ? 394.583 361.017 199.813 1.00 109.79 ? 6   SER D O     1 
ATOM   10111 C  CB    . SER D 2 6   ? 392.842 362.333 197.840 1.00 99.97  ? 6   SER D CB    1 
ATOM   10112 O  OG    . SER D 2 6   ? 392.335 362.566 196.539 1.00 109.24 ? 6   SER D OG    1 
ATOM   10113 N  N     . ILE D 2 7   ? 395.677 362.994 199.795 1.00 94.64  ? 7   ILE D N     1 
ATOM   10114 C  CA    . ILE D 2 7   ? 396.241 362.878 201.137 1.00 93.68  ? 7   ILE D CA    1 
ATOM   10115 C  C     . ILE D 2 7   ? 395.512 363.874 202.026 1.00 90.78  ? 7   ILE D C     1 
ATOM   10116 O  O     . ILE D 2 7   ? 395.437 365.065 201.704 1.00 97.63  ? 7   ILE D O     1 
ATOM   10117 C  CB    . ILE D 2 7   ? 397.759 363.121 201.154 1.00 99.69  ? 7   ILE D CB    1 
ATOM   10118 C  CG1   . ILE D 2 7   ? 398.503 362.054 200.336 1.00 99.93  ? 7   ILE D CG1   1 
ATOM   10119 C  CG2   . ILE D 2 7   ? 398.274 363.127 202.586 1.00 102.34 ? 7   ILE D CG2   1 
ATOM   10120 C  CD1   . ILE D 2 7   ? 399.842 362.510 199.811 1.00 100.77 ? 7   ILE D CD1   1 
ATOM   10121 N  N     . HIS D 2 8   ? 394.975 363.381 203.139 1.00 85.64  ? 8   HIS D N     1 
ATOM   10122 C  CA    . HIS D 2 8   ? 394.133 364.152 204.049 1.00 90.47  ? 8   HIS D CA    1 
ATOM   10123 C  C     . HIS D 2 8   ? 394.830 364.227 205.400 1.00 100.83 ? 8   HIS D C     1 
ATOM   10124 O  O     . HIS D 2 8   ? 394.965 363.211 206.090 1.00 112.02 ? 8   HIS D O     1 
ATOM   10125 C  CB    . HIS D 2 8   ? 392.753 363.509 204.153 1.00 104.79 ? 8   HIS D CB    1 
ATOM   10126 C  CG    . HIS D 2 8   ? 392.079 363.332 202.828 1.00 104.79 ? 8   HIS D CG    1 
ATOM   10127 N  ND1   . HIS D 2 8   ? 391.253 364.290 202.280 1.00 102.07 ? 8   HIS D ND1   1 
ATOM   10128 C  CD2   . HIS D 2 8   ? 392.122 362.317 201.933 1.00 106.43 ? 8   HIS D CD2   1 
ATOM   10129 C  CE1   . HIS D 2 8   ? 390.810 363.868 201.110 1.00 101.25 ? 8   HIS D CE1   1 
ATOM   10130 N  NE2   . HIS D 2 8   ? 391.321 362.673 200.876 1.00 97.51  ? 8   HIS D NE2   1 
ATOM   10131 N  N     . VAL D 2 9   ? 395.250 365.435 205.778 1.00 100.18 ? 9   VAL D N     1 
ATOM   10132 C  CA    . VAL D 2 9   ? 396.133 365.671 206.916 1.00 100.87 ? 9   VAL D CA    1 
ATOM   10133 C  C     . VAL D 2 9   ? 395.394 366.518 207.940 1.00 100.15 ? 9   VAL D C     1 
ATOM   10134 O  O     . VAL D 2 9   ? 394.777 367.529 207.587 1.00 105.42 ? 9   VAL D O     1 
ATOM   10135 C  CB    . VAL D 2 9   ? 397.438 366.368 206.490 1.00 102.67 ? 9   VAL D CB    1 
ATOM   10136 C  CG1   . VAL D 2 9   ? 398.500 366.221 207.572 1.00 107.57 ? 9   VAL D CG1   1 
ATOM   10137 C  CG2   . VAL D 2 9   ? 397.935 365.816 205.161 1.00 104.21 ? 9   VAL D CG2   1 
ATOM   10138 N  N     . GLY D 2 10  ? 395.468 366.111 209.203 1.00 99.64  ? 10  GLY D N     1 
ATOM   10139 C  CA    . GLY D 2 10  ? 394.860 366.874 210.273 1.00 103.72 ? 10  GLY D CA    1 
ATOM   10140 C  C     . GLY D 2 10  ? 393.363 366.678 210.340 1.00 104.33 ? 10  GLY D C     1 
ATOM   10141 O  O     . GLY D 2 10  ? 392.782 366.038 209.459 1.00 108.47 ? 10  GLY D O     1 
ATOM   10142 N  N     . GLN D 2 11  ? 392.734 367.234 211.380 1.00 98.34  ? 11  GLN D N     1 
ATOM   10143 C  CA    . GLN D 2 11  ? 391.297 367.060 211.570 1.00 94.04  ? 11  GLN D CA    1 
ATOM   10144 C  C     . GLN D 2 11  ? 390.519 367.667 210.413 1.00 89.86  ? 11  GLN D C     1 
ATOM   10145 O  O     . GLN D 2 11  ? 389.566 367.066 209.903 1.00 97.15  ? 11  GLN D O     1 
ATOM   10146 C  CB    . GLN D 2 11  ? 390.870 367.687 212.896 1.00 93.50  ? 11  GLN D CB    1 
ATOM   10147 C  CG    . GLN D 2 11  ? 389.369 367.743 213.113 1.00 91.38  ? 11  GLN D CG    1 
ATOM   10148 C  CD    . GLN D 2 11  ? 389.004 367.850 214.579 1.00 91.17  ? 11  GLN D CD    1 
ATOM   10149 O  OE1   . GLN D 2 11  ? 389.801 368.309 215.395 1.00 92.78  ? 11  GLN D OE1   1 
ATOM   10150 N  NE2   . GLN D 2 11  ? 387.795 367.424 214.923 1.00 95.62  ? 11  GLN D NE2   1 
ATOM   10151 N  N     . ALA D 2 12  ? 390.923 368.860 209.978 1.00 73.13  ? 12  ALA D N     1 
ATOM   10152 C  CA    . ALA D 2 12  ? 390.236 369.504 208.867 1.00 82.80  ? 12  ALA D CA    1 
ATOM   10153 C  C     . ALA D 2 12  ? 390.394 368.709 207.587 1.00 91.21  ? 12  ALA D C     1 
ATOM   10154 O  O     . ALA D 2 12  ? 389.419 368.505 206.849 1.00 101.32 ? 12  ALA D O     1 
ATOM   10155 C  CB    . ALA D 2 12  ? 390.768 370.922 208.674 1.00 81.27  ? 12  ALA D CB    1 
ATOM   10156 N  N     . GLY D 2 13  ? 391.611 368.236 207.320 1.00 97.27  ? 13  GLY D N     1 
ATOM   10157 C  CA    . GLY D 2 13  ? 391.844 367.464 206.115 1.00 98.05  ? 13  GLY D CA    1 
ATOM   10158 C  C     . GLY D 2 13  ? 391.028 366.189 206.081 1.00 96.80  ? 13  GLY D C     1 
ATOM   10159 O  O     . GLY D 2 13  ? 390.375 365.887 205.083 1.00 100.76 ? 13  GLY D O     1 
ATOM   10160 N  N     . VAL D 2 14  ? 391.021 365.441 207.187 1.00 97.07  ? 14  VAL D N     1 
ATOM   10161 C  CA    . VAL D 2 14  ? 390.309 364.166 207.186 1.00 97.55  ? 14  VAL D CA    1 
ATOM   10162 C  C     . VAL D 2 14  ? 388.798 364.380 207.155 1.00 99.08  ? 14  VAL D C     1 
ATOM   10163 O  O     . VAL D 2 14  ? 388.079 363.614 206.510 1.00 109.80 ? 14  VAL D O     1 
ATOM   10164 C  CB    . VAL D 2 14  ? 390.733 363.276 208.371 1.00 99.33  ? 14  VAL D CB    1 
ATOM   10165 C  CG1   . VAL D 2 14  ? 392.226 362.955 208.302 1.00 98.55  ? 14  VAL D CG1   1 
ATOM   10166 C  CG2   . VAL D 2 14  ? 390.356 363.884 209.703 1.00 106.96 ? 14  VAL D CG2   1 
ATOM   10167 N  N     . GLN D 2 15  ? 388.279 365.400 207.851 1.00 90.64  ? 15  GLN D N     1 
ATOM   10168 C  CA    . GLN D 2 15  ? 386.833 365.625 207.822 1.00 92.95  ? 15  GLN D CA    1 
ATOM   10169 C  C     . GLN D 2 15  ? 386.366 366.060 206.436 1.00 92.75  ? 15  GLN D C     1 
ATOM   10170 O  O     . GLN D 2 15  ? 385.339 365.570 205.926 1.00 100.48 ? 15  GLN D O     1 
ATOM   10171 C  CB    . GLN D 2 15  ? 386.445 366.664 208.871 1.00 90.87  ? 15  GLN D CB    1 
ATOM   10172 C  CG    . GLN D 2 15  ? 386.432 366.138 210.298 1.00 95.91  ? 15  GLN D CG    1 
ATOM   10173 C  CD    . GLN D 2 15  ? 385.636 367.021 211.235 1.00 100.05 ? 15  GLN D CD    1 
ATOM   10174 O  OE1   . GLN D 2 15  ? 386.113 368.065 211.676 1.00 98.52  ? 15  GLN D OE1   1 
ATOM   10175 N  NE2   . GLN D 2 15  ? 384.414 366.606 211.546 1.00 102.91 ? 15  GLN D NE2   1 
ATOM   10176 N  N     . ILE D 2 16  ? 387.116 366.965 205.800 1.00 82.67  ? 16  ILE D N     1 
ATOM   10177 C  CA    . ILE D 2 16  ? 386.801 367.331 204.426 1.00 84.34  ? 16  ILE D CA    1 
ATOM   10178 C  C     . ILE D 2 16  ? 386.950 366.118 203.520 1.00 91.97  ? 16  ILE D C     1 
ATOM   10179 O  O     . ILE D 2 16  ? 386.196 365.957 202.562 1.00 94.33  ? 16  ILE D O     1 
ATOM   10180 C  CB    . ILE D 2 16  ? 387.674 368.514 203.966 1.00 87.74  ? 16  ILE D CB    1 
ATOM   10181 C  CG1   . ILE D 2 16  ? 387.216 369.804 204.651 1.00 92.25  ? 16  ILE D CG1   1 
ATOM   10182 C  CG2   . ILE D 2 16  ? 387.595 368.707 202.451 1.00 92.35  ? 16  ILE D CG2   1 
ATOM   10183 C  CD1   . ILE D 2 16  ? 388.294 370.848 204.785 1.00 97.45  ? 16  ILE D CD1   1 
ATOM   10184 N  N     . GLY D 2 17  ? 387.903 365.234 203.822 1.00 102.68 ? 17  GLY D N     1 
ATOM   10185 C  CA    . GLY D 2 17  ? 388.029 364.010 203.051 1.00 101.42 ? 17  GLY D CA    1 
ATOM   10186 C  C     . GLY D 2 17  ? 386.833 363.092 203.205 1.00 105.16 ? 17  GLY D C     1 
ATOM   10187 O  O     . GLY D 2 17  ? 386.438 362.416 202.256 1.00 111.29 ? 17  GLY D O     1 
ATOM   10188 N  N     . ASN D 2 18  ? 386.246 363.049 204.403 1.00 107.85 ? 18  ASN D N     1 
ATOM   10189 C  CA    . ASN D 2 18  ? 385.031 362.258 204.602 1.00 103.38 ? 18  ASN D CA    1 
ATOM   10190 C  C     . ASN D 2 18  ? 383.908 362.786 203.730 1.00 99.12  ? 18  ASN D C     1 
ATOM   10191 O  O     . ASN D 2 18  ? 383.237 362.019 203.025 1.00 102.65 ? 18  ASN D O     1 
ATOM   10192 C  CB    . ASN D 2 18  ? 384.581 362.250 206.075 1.00 102.32 ? 18  ASN D CB    1 
ATOM   10193 C  CG    . ASN D 2 18  ? 385.705 361.963 207.096 1.00 113.40 ? 18  ASN D CG    1 
ATOM   10194 O  OD1   . ASN D 2 18  ? 386.755 361.462 206.697 1.00 122.24 ? 18  ASN D OD1   1 
ATOM   10195 N  ND2   . ASN D 2 18  ? 385.546 362.368 208.363 1.00 110.31 ? 18  ASN D ND2   1 
ATOM   10196 N  N     . ALA D 2 19  ? 383.713 364.107 203.740 1.00 96.55  ? 19  ALA D N     1 
ATOM   10197 C  CA    . ALA D 2 19  ? 382.683 364.691 202.881 1.00 97.45  ? 19  ALA D CA    1 
ATOM   10198 C  C     . ALA D 2 19  ? 382.997 364.462 201.404 1.00 99.81  ? 19  ALA D C     1 
ATOM   10199 O  O     . ALA D 2 19  ? 382.102 364.149 200.607 1.00 108.18 ? 19  ALA D O     1 
ATOM   10200 C  CB    . ALA D 2 19  ? 382.536 366.181 203.171 1.00 100.34 ? 19  ALA D CB    1 
ATOM   10201 N  N     . CYS D 2 20  ? 384.272 364.581 201.030 1.00 103.28 ? 20  CYS D N     1 
ATOM   10202 C  CA    . CYS D 2 20  ? 384.675 364.424 199.638 1.00 103.27 ? 20  CYS D CA    1 
ATOM   10203 C  C     . CYS D 2 20  ? 384.431 363.006 199.148 1.00 106.02 ? 20  CYS D C     1 
ATOM   10204 O  O     . CYS D 2 20  ? 383.883 362.804 198.062 1.00 110.55 ? 20  CYS D O     1 
ATOM   10205 C  CB    . CYS D 2 20  ? 386.149 364.799 199.485 1.00 99.35  ? 20  CYS D CB    1 
ATOM   10206 S  SG    . CYS D 2 20  ? 386.475 366.570 199.579 1.00 125.06 ? 20  CYS D SG    1 
ATOM   10207 N  N     . TRP D 2 21  ? 384.825 362.008 199.939 1.00 94.45  ? 21  TRP D N     1 
ATOM   10208 C  CA    . TRP D 2 21  ? 384.650 360.628 199.511 1.00 89.91  ? 21  TRP D CA    1 
ATOM   10209 C  C     . TRP D 2 21  ? 383.189 360.213 199.560 1.00 96.99  ? 21  TRP D C     1 
ATOM   10210 O  O     . TRP D 2 21  ? 382.764 359.387 198.745 1.00 102.34 ? 21  TRP D O     1 
ATOM   10211 C  CB    . TRP D 2 21  ? 385.526 359.705 200.354 1.00 95.93  ? 21  TRP D CB    1 
ATOM   10212 C  CG    . TRP D 2 21  ? 386.975 359.804 199.969 1.00 99.23  ? 21  TRP D CG    1 
ATOM   10213 C  CD1   . TRP D 2 21  ? 387.992 360.310 200.720 1.00 103.58 ? 21  TRP D CD1   1 
ATOM   10214 C  CD2   . TRP D 2 21  ? 387.560 359.399 198.725 1.00 98.59  ? 21  TRP D CD2   1 
ATOM   10215 N  NE1   . TRP D 2 21  ? 389.174 360.243 200.025 1.00 103.15 ? 21  TRP D NE1   1 
ATOM   10216 C  CE2   . TRP D 2 21  ? 388.935 359.687 198.797 1.00 97.55  ? 21  TRP D CE2   1 
ATOM   10217 C  CE3   . TRP D 2 21  ? 387.054 358.819 197.560 1.00 101.10 ? 21  TRP D CE3   1 
ATOM   10218 C  CZ2   . TRP D 2 21  ? 389.809 359.414 197.749 1.00 96.69  ? 21  TRP D CZ2   1 
ATOM   10219 C  CZ3   . TRP D 2 21  ? 387.922 358.549 196.522 1.00 96.51  ? 21  TRP D CZ3   1 
ATOM   10220 C  CH2   . TRP D 2 21  ? 389.283 358.847 196.623 1.00 96.15  ? 21  TRP D CH2   1 
ATOM   10221 N  N     . GLU D 2 22  ? 382.400 360.798 200.467 1.00 103.25 ? 22  GLU D N     1 
ATOM   10222 C  CA    . GLU D 2 22  ? 380.951 360.642 200.387 1.00 97.88  ? 22  GLU D CA    1 
ATOM   10223 C  C     . GLU D 2 22  ? 380.430 361.147 199.046 1.00 98.16  ? 22  GLU D C     1 
ATOM   10224 O  O     . GLU D 2 22  ? 379.636 360.471 198.378 1.00 97.95  ? 22  GLU D O     1 
ATOM   10225 C  CB    . GLU D 2 22  ? 380.289 361.388 201.549 1.00 104.63 ? 22  GLU D CB    1 
ATOM   10226 C  CG    . GLU D 2 22  ? 378.778 361.563 201.442 1.00 108.43 ? 22  GLU D CG    1 
ATOM   10227 C  CD    . GLU D 2 22  ? 378.158 362.002 202.751 1.00 112.22 ? 22  GLU D CD    1 
ATOM   10228 O  OE1   . GLU D 2 22  ? 378.652 362.985 203.341 1.00 105.71 ? 22  GLU D OE1   1 
ATOM   10229 O  OE2   . GLU D 2 22  ? 377.175 361.369 203.189 1.00 114.65 ? 22  GLU D OE2   1 
ATOM   10230 N  N     . LEU D 2 23  ? 380.891 362.326 198.624 1.00 101.33 ? 23  LEU D N     1 
ATOM   10231 C  CA    . LEU D 2 23  ? 380.424 362.880 197.356 1.00 96.53  ? 23  LEU D CA    1 
ATOM   10232 C  C     . LEU D 2 23  ? 380.879 362.036 196.169 1.00 95.70  ? 23  LEU D C     1 
ATOM   10233 O  O     . LEU D 2 23  ? 380.110 361.829 195.224 1.00 100.93 ? 23  LEU D O     1 
ATOM   10234 C  CB    . LEU D 2 23  ? 380.901 364.323 197.200 1.00 100.25 ? 23  LEU D CB    1 
ATOM   10235 C  CG    . LEU D 2 23  ? 380.495 365.056 195.913 1.00 102.24 ? 23  LEU D CG    1 
ATOM   10236 C  CD1   . LEU D 2 23  ? 378.987 365.092 195.715 1.00 106.54 ? 23  LEU D CD1   1 
ATOM   10237 C  CD2   . LEU D 2 23  ? 381.045 366.453 195.952 1.00 109.81 ? 23  LEU D CD2   1 
ATOM   10238 N  N     . TYR D 2 24  ? 382.131 361.566 196.180 1.00 99.91  ? 24  TYR D N     1 
ATOM   10239 C  CA    . TYR D 2 24  ? 382.602 360.743 195.068 1.00 103.46 ? 24  TYR D CA    1 
ATOM   10240 C  C     . TYR D 2 24  ? 381.839 359.428 194.998 1.00 105.80 ? 24  TYR D C     1 
ATOM   10241 O  O     . TYR D 2 24  ? 381.517 358.948 193.904 1.00 107.48 ? 24  TYR D O     1 
ATOM   10242 C  CB    . TYR D 2 24  ? 384.104 360.454 195.153 1.00 103.43 ? 24  TYR D CB    1 
ATOM   10243 C  CG    . TYR D 2 24  ? 385.029 361.653 195.147 1.00 100.87 ? 24  TYR D CG    1 
ATOM   10244 C  CD1   . TYR D 2 24  ? 385.033 362.549 194.087 1.00 100.18 ? 24  TYR D CD1   1 
ATOM   10245 C  CD2   . TYR D 2 24  ? 385.979 361.821 196.142 1.00 105.33 ? 24  TYR D CD2   1 
ATOM   10246 C  CE1   . TYR D 2 24  ? 385.901 363.625 194.066 1.00 102.56 ? 24  TYR D CE1   1 
ATOM   10247 C  CE2   . TYR D 2 24  ? 386.846 362.885 196.129 1.00 108.66 ? 24  TYR D CE2   1 
ATOM   10248 C  CZ    . TYR D 2 24  ? 386.809 363.781 195.088 1.00 109.82 ? 24  TYR D CZ    1 
ATOM   10249 O  OH    . TYR D 2 24  ? 387.689 364.834 195.088 1.00 117.41 ? 24  TYR D OH    1 
ATOM   10250 N  N     . CYS D 2 25  ? 381.558 358.820 196.153 1.00 112.06 ? 25  CYS D N     1 
ATOM   10251 C  CA    . CYS D 2 25  ? 380.774 357.593 196.168 1.00 112.55 ? 25  CYS D CA    1 
ATOM   10252 C  C     . CYS D 2 25  ? 379.371 357.834 195.628 1.00 116.99 ? 25  CYS D C     1 
ATOM   10253 O  O     . CYS D 2 25  ? 378.843 357.016 194.867 1.00 122.41 ? 25  CYS D O     1 
ATOM   10254 C  CB    . CYS D 2 25  ? 380.715 357.034 197.587 1.00 113.65 ? 25  CYS D CB    1 
ATOM   10255 S  SG    . CYS D 2 25  ? 382.224 356.196 198.107 1.00 127.06 ? 25  CYS D SG    1 
ATOM   10256 N  N     . LEU D 2 26  ? 378.755 358.958 196.003 1.00 106.34 ? 26  LEU D N     1 
ATOM   10257 C  CA    . LEU D 2 26  ? 377.428 359.273 195.478 1.00 101.54 ? 26  LEU D CA    1 
ATOM   10258 C  C     . LEU D 2 26  ? 377.465 359.509 193.971 1.00 97.63  ? 26  LEU D C     1 
ATOM   10259 O  O     . LEU D 2 26  ? 376.559 359.080 193.248 1.00 104.84 ? 26  LEU D O     1 
ATOM   10260 C  CB    . LEU D 2 26  ? 376.844 360.495 196.194 1.00 104.86 ? 26  LEU D CB    1 
ATOM   10261 C  CG    . LEU D 2 26  ? 375.895 360.231 197.371 1.00 104.56 ? 26  LEU D CG    1 
ATOM   10262 C  CD1   . LEU D 2 26  ? 374.523 359.815 196.860 1.00 101.66 ? 26  LEU D CD1   1 
ATOM   10263 C  CD2   . LEU D 2 26  ? 376.440 359.187 198.343 1.00 102.55 ? 26  LEU D CD2   1 
ATOM   10264 N  N     . GLU D 2 27  ? 378.501 360.190 193.478 1.00 106.64 ? 27  GLU D N     1 
ATOM   10265 C  CA    . GLU D 2 27  ? 378.582 360.480 192.048 1.00 113.22 ? 27  GLU D CA    1 
ATOM   10266 C  C     . GLU D 2 27  ? 378.820 359.215 191.233 1.00 115.69 ? 27  GLU D C     1 
ATOM   10267 O  O     . GLU D 2 27  ? 378.147 358.985 190.222 1.00 118.21 ? 27  GLU D O     1 
ATOM   10268 C  CB    . GLU D 2 27  ? 379.680 361.516 191.782 1.00 117.97 ? 27  GLU D CB    1 
ATOM   10269 C  CG    . GLU D 2 27  ? 379.241 362.948 192.052 1.00 122.44 ? 27  GLU D CG    1 
ATOM   10270 C  CD    . GLU D 2 27  ? 380.196 363.987 191.508 1.00 122.89 ? 27  GLU D CD    1 
ATOM   10271 O  OE1   . GLU D 2 27  ? 381.413 363.871 191.749 1.00 123.32 ? 27  GLU D OE1   1 
ATOM   10272 O  OE2   . GLU D 2 27  ? 379.725 364.930 190.836 1.00 123.27 ? 27  GLU D OE2   1 
ATOM   10273 N  N     . HIS D 2 28  ? 379.764 358.377 191.659 1.00 118.65 ? 28  HIS D N     1 
ATOM   10274 C  CA    . HIS D 2 28  ? 380.083 357.161 190.922 1.00 117.83 ? 28  HIS D CA    1 
ATOM   10275 C  C     . HIS D 2 28  ? 379.157 355.994 191.242 1.00 116.16 ? 28  HIS D C     1 
ATOM   10276 O  O     . HIS D 2 28  ? 379.302 354.932 190.627 1.00 122.55 ? 28  HIS D O     1 
ATOM   10277 C  CB    . HIS D 2 28  ? 381.527 356.749 191.203 1.00 119.00 ? 28  HIS D CB    1 
ATOM   10278 C  CG    . HIS D 2 28  ? 382.544 357.656 190.590 1.00 117.06 ? 28  HIS D CG    1 
ATOM   10279 N  ND1   . HIS D 2 28  ? 383.491 358.325 191.333 1.00 120.62 ? 28  HIS D ND1   1 
ATOM   10280 C  CD2   . HIS D 2 28  ? 382.763 358.002 189.301 1.00 117.28 ? 28  HIS D CD2   1 
ATOM   10281 C  CE1   . HIS D 2 28  ? 384.252 359.043 190.527 1.00 123.34 ? 28  HIS D CE1   1 
ATOM   10282 N  NE2   . HIS D 2 28  ? 383.830 358.866 189.288 1.00 124.20 ? 28  HIS D NE2   1 
ATOM   10283 N  N     . GLY D 2 29  ? 378.221 356.148 192.178 1.00 102.89 ? 29  GLY D N     1 
ATOM   10284 C  CA    . GLY D 2 29  ? 377.332 355.062 192.523 1.00 106.47 ? 29  GLY D CA    1 
ATOM   10285 C  C     . GLY D 2 29  ? 377.933 354.000 193.415 1.00 102.17 ? 29  GLY D C     1 
ATOM   10286 O  O     . GLY D 2 29  ? 377.306 352.953 193.606 1.00 102.70 ? 29  GLY D O     1 
ATOM   10287 N  N     . ILE D 2 30  ? 379.124 354.228 193.967 1.00 101.11 ? 30  ILE D N     1 
ATOM   10288 C  CA    . ILE D 2 30  ? 379.749 353.253 194.852 1.00 98.59  ? 30  ILE D CA    1 
ATOM   10289 C  C     . ILE D 2 30  ? 379.010 353.292 196.182 1.00 105.89 ? 30  ILE D C     1 
ATOM   10290 O  O     . ILE D 2 30  ? 378.742 354.367 196.730 1.00 116.36 ? 30  ILE D O     1 
ATOM   10291 C  CB    . ILE D 2 30  ? 381.263 353.536 195.023 1.00 106.55 ? 30  ILE D CB    1 
ATOM   10292 C  CG1   . ILE D 2 30  ? 382.103 352.937 193.870 1.00 111.43 ? 30  ILE D CG1   1 
ATOM   10293 C  CG2   . ILE D 2 30  ? 381.821 352.969 196.364 1.00 109.91 ? 30  ILE D CG2   1 
ATOM   10294 C  CD1   . ILE D 2 30  ? 381.946 353.562 192.504 1.00 112.51 ? 30  ILE D CD1   1 
ATOM   10295 N  N     . GLN D 2 31  ? 378.679 352.120 196.708 1.00 108.72 ? 31  GLN D N     1 
ATOM   10296 C  CA    . GLN D 2 31  ? 378.062 352.041 198.018 1.00 110.15 ? 31  GLN D CA    1 
ATOM   10297 C  C     . GLN D 2 31  ? 379.103 352.309 199.104 1.00 110.13 ? 31  GLN D C     1 
ATOM   10298 O  O     . GLN D 2 31  ? 380.305 352.226 198.847 1.00 112.70 ? 31  GLN D O     1 
ATOM   10299 C  CB    . GLN D 2 31  ? 377.432 350.667 198.220 1.00 104.40 ? 31  GLN D CB    1 
ATOM   10300 C  CG    . GLN D 2 31  ? 376.092 350.492 197.524 1.00 105.44 ? 31  GLN D CG    1 
ATOM   10301 C  CD    . GLN D 2 31  ? 375.579 349.069 197.605 1.00 113.10 ? 31  GLN D CD    1 
ATOM   10302 O  OE1   . GLN D 2 31  ? 376.224 348.198 198.188 1.00 110.54 ? 31  GLN D OE1   1 
ATOM   10303 N  NE2   . GLN D 2 31  ? 374.409 348.826 197.027 1.00 115.92 ? 31  GLN D NE2   1 
ATOM   10304 N  N     . PRO D 2 32  ? 378.677 352.642 200.330 1.00 101.73 ? 32  PRO D N     1 
ATOM   10305 C  CA    . PRO D 2 32  ? 379.666 352.770 201.416 1.00 101.32 ? 32  PRO D CA    1 
ATOM   10306 C  C     . PRO D 2 32  ? 380.400 351.474 201.715 1.00 103.26 ? 32  PRO D C     1 
ATOM   10307 O  O     . PRO D 2 32  ? 381.524 351.511 202.229 1.00 101.95 ? 32  PRO D O     1 
ATOM   10308 C  CB    . PRO D 2 32  ? 378.823 353.235 202.613 1.00 102.60 ? 32  PRO D CB    1 
ATOM   10309 C  CG    . PRO D 2 32  ? 377.428 352.876 202.272 1.00 102.35 ? 32  PRO D CG    1 
ATOM   10310 C  CD    . PRO D 2 32  ? 377.324 353.000 200.793 1.00 101.57 ? 32  PRO D CD    1 
ATOM   10311 N  N     . ASP D 2 33  ? 379.795 350.325 201.406 1.00 111.76 ? 33  ASP D N     1 
ATOM   10312 C  CA    . ASP D 2 33  ? 380.493 349.049 201.499 1.00 114.18 ? 33  ASP D CA    1 
ATOM   10313 C  C     . ASP D 2 33  ? 381.651 348.942 200.512 1.00 111.99 ? 33  ASP D C     1 
ATOM   10314 O  O     . ASP D 2 33  ? 382.574 348.157 200.752 1.00 109.75 ? 33  ASP D O     1 
ATOM   10315 C  CB    . ASP D 2 33  ? 379.504 347.906 201.262 1.00 113.93 ? 33  ASP D CB    1 
ATOM   10316 C  CG    . ASP D 2 33  ? 380.094 346.542 201.569 1.00 120.19 ? 33  ASP D CG    1 
ATOM   10317 O  OD1   . ASP D 2 33  ? 381.102 346.466 202.303 1.00 120.06 ? 33  ASP D OD1   1 
ATOM   10318 O  OD2   . ASP D 2 33  ? 379.545 345.537 201.071 1.00 118.65 ? 33  ASP D OD2   1 
ATOM   10319 N  N     . GLY D 2 34  ? 381.623 349.711 199.417 1.00 104.48 ? 34  GLY D N     1 
ATOM   10320 C  CA    . GLY D 2 34  ? 382.636 349.671 198.382 1.00 100.08 ? 34  GLY D CA    1 
ATOM   10321 C  C     . GLY D 2 34  ? 382.209 348.987 197.099 1.00 98.84  ? 34  GLY D C     1 
ATOM   10322 O  O     . GLY D 2 34  ? 382.902 349.133 196.085 1.00 103.04 ? 34  GLY D O     1 
ATOM   10323 N  N     . GLN D 2 35  ? 381.099 348.253 197.109 1.00 99.77  ? 35  GLN D N     1 
ATOM   10324 C  CA    . GLN D 2 35  ? 380.625 347.567 195.918 1.00 101.06 ? 35  GLN D CA    1 
ATOM   10325 C  C     . GLN D 2 35  ? 379.813 348.504 195.035 1.00 98.46  ? 35  GLN D C     1 
ATOM   10326 O  O     . GLN D 2 35  ? 379.122 349.408 195.515 1.00 104.40 ? 35  GLN D O     1 
ATOM   10327 C  CB    . GLN D 2 35  ? 379.766 346.360 196.299 1.00 106.75 ? 35  GLN D CB    1 
ATOM   10328 C  CG    . GLN D 2 35  ? 380.481 345.289 197.115 1.00 107.72 ? 35  GLN D CG    1 
ATOM   10329 C  CD    . GLN D 2 35  ? 381.641 344.655 196.369 1.00 111.45 ? 35  GLN D CD    1 
ATOM   10330 O  OE1   . GLN D 2 35  ? 381.535 344.349 195.182 1.00 109.65 ? 35  GLN D OE1   1 
ATOM   10331 N  NE2   . GLN D 2 35  ? 382.753 344.451 197.063 1.00 111.47 ? 35  GLN D NE2   1 
ATOM   10332 N  N     . MET D 2 36  ? 379.902 348.270 193.725 1.00 108.05 ? 36  MET D N     1 
ATOM   10333 C  CA    . MET D 2 36  ? 379.077 348.955 192.744 1.00 115.68 ? 36  MET D CA    1 
ATOM   10334 C  C     . MET D 2 36  ? 377.825 348.115 192.517 1.00 115.98 ? 36  MET D C     1 
ATOM   10335 O  O     . MET D 2 36  ? 377.939 347.015 191.955 1.00 118.96 ? 36  MET D O     1 
ATOM   10336 C  CB    . MET D 2 36  ? 379.842 349.132 191.433 1.00 115.83 ? 36  MET D CB    1 
ATOM   10337 C  CG    . MET D 2 36  ? 379.085 349.905 190.362 1.00 117.48 ? 36  MET D CG    1 
ATOM   10338 S  SD    . MET D 2 36  ? 380.060 350.189 188.883 1.00 131.31 ? 36  MET D SD    1 
ATOM   10339 C  CE    . MET D 2 36  ? 381.093 351.543 189.428 1.00 121.56 ? 36  MET D CE    1 
ATOM   10340 N  N     . PRO D 2 37  ? 376.619 348.558 192.906 1.00 115.15 ? 37  PRO D N     1 
ATOM   10341 C  CA    . PRO D 2 37  ? 375.449 347.692 192.692 1.00 117.04 ? 37  PRO D CA    1 
ATOM   10342 C  C     . PRO D 2 37  ? 375.042 347.568 191.235 1.00 120.62 ? 37  PRO D C     1 
ATOM   10343 O  O     . PRO D 2 37  ? 374.362 346.596 190.884 1.00 113.88 ? 37  PRO D O     1 
ATOM   10344 C  CB    . PRO D 2 37  ? 374.356 348.368 193.525 1.00 114.88 ? 37  PRO D CB    1 
ATOM   10345 C  CG    . PRO D 2 37  ? 374.699 349.795 193.477 1.00 116.58 ? 37  PRO D CG    1 
ATOM   10346 C  CD    . PRO D 2 37  ? 376.206 349.870 193.446 1.00 119.39 ? 37  PRO D CD    1 
ATOM   10347 N  N     . SER D 2 38  ? 375.437 348.505 190.378 1.00 128.04 ? 38  SER D N     1 
ATOM   10348 C  CA    . SER D 2 38  ? 375.093 348.440 188.963 1.00 127.30 ? 38  SER D CA    1 
ATOM   10349 C  C     . SER D 2 38  ? 375.870 347.325 188.271 1.00 123.04 ? 38  SER D C     1 
ATOM   10350 O  O     . SER D 2 38  ? 377.072 347.446 188.033 1.00 120.78 ? 38  SER D O     1 
ATOM   10351 C  CB    . SER D 2 38  ? 375.375 349.781 188.280 1.00 127.30 ? 38  SER D CB    1 
ATOM   10352 O  OG    . SER D 2 38  ? 374.932 349.774 186.934 1.00 126.00 ? 38  SER D OG    1 
ATOM   10353 N  N     . GLY D 2 43  ? 377.761 353.168 181.666 1.00 181.08 ? 43  GLY D N     1 
ATOM   10354 C  CA    . GLY D 2 43  ? 378.881 352.816 180.813 1.00 181.63 ? 43  GLY D CA    1 
ATOM   10355 C  C     . GLY D 2 43  ? 380.022 353.809 180.918 1.00 182.60 ? 43  GLY D C     1 
ATOM   10356 O  O     . GLY D 2 43  ? 381.175 353.427 181.117 1.00 182.47 ? 43  GLY D O     1 
ATOM   10357 N  N     . GLY D 2 44  ? 379.695 355.096 180.786 1.00 195.29 ? 44  GLY D N     1 
ATOM   10358 C  CA    . GLY D 2 44  ? 380.694 356.139 180.942 1.00 195.75 ? 44  GLY D CA    1 
ATOM   10359 C  C     . GLY D 2 44  ? 381.206 356.299 182.359 1.00 195.64 ? 44  GLY D C     1 
ATOM   10360 O  O     . GLY D 2 44  ? 382.241 356.942 182.563 1.00 192.90 ? 44  GLY D O     1 
ATOM   10361 N  N     . GLY D 2 45  ? 380.503 355.736 183.345 1.00 178.70 ? 45  GLY D N     1 
ATOM   10362 C  CA    . GLY D 2 45  ? 380.929 355.858 184.724 1.00 175.16 ? 45  GLY D CA    1 
ATOM   10363 C  C     . GLY D 2 45  ? 382.157 355.046 185.080 1.00 178.97 ? 45  GLY D C     1 
ATOM   10364 O  O     . GLY D 2 45  ? 382.803 355.351 186.082 1.00 177.35 ? 45  GLY D O     1 
ATOM   10365 N  N     . ASP D 2 46  ? 382.504 354.030 184.285 1.00 169.58 ? 46  ASP D N     1 
ATOM   10366 C  CA    . ASP D 2 46  ? 383.595 353.130 184.663 1.00 163.47 ? 46  ASP D CA    1 
ATOM   10367 C  C     . ASP D 2 46  ? 384.954 353.826 184.601 1.00 159.50 ? 46  ASP D C     1 
ATOM   10368 O  O     . ASP D 2 46  ? 385.743 353.760 185.554 1.00 157.05 ? 46  ASP D O     1 
ATOM   10369 C  CB    . ASP D 2 46  ? 383.584 351.897 183.761 1.00 161.82 ? 46  ASP D CB    1 
ATOM   10370 C  CG    . ASP D 2 46  ? 382.256 351.167 183.790 1.00 163.15 ? 46  ASP D CG    1 
ATOM   10371 O  OD1   . ASP D 2 46  ? 381.418 351.493 184.658 1.00 164.87 ? 46  ASP D OD1   1 
ATOM   10372 O  OD2   . ASP D 2 46  ? 382.048 350.272 182.945 1.00 160.65 ? 46  ASP D OD2   1 
ATOM   10373 N  N     . ASP D 2 47  ? 385.252 354.484 183.478 1.00 140.96 ? 47  ASP D N     1 
ATOM   10374 C  CA    . ASP D 2 47  ? 386.525 355.189 183.349 1.00 140.85 ? 47  ASP D CA    1 
ATOM   10375 C  C     . ASP D 2 47  ? 386.586 356.348 184.338 1.00 142.11 ? 47  ASP D C     1 
ATOM   10376 O  O     . ASP D 2 47  ? 387.640 356.621 184.925 1.00 137.92 ? 47  ASP D O     1 
ATOM   10377 C  CB    . ASP D 2 47  ? 386.690 355.674 181.902 1.00 146.61 ? 47  ASP D CB    1 
ATOM   10378 C  CG    . ASP D 2 47  ? 388.025 356.385 181.635 1.00 150.20 ? 47  ASP D CG    1 
ATOM   10379 O  OD1   . ASP D 2 47  ? 388.878 356.525 182.537 1.00 148.13 ? 47  ASP D OD1   1 
ATOM   10380 O  OD2   . ASP D 2 47  ? 388.220 356.816 180.479 1.00 148.74 ? 47  ASP D OD2   1 
ATOM   10381 N  N     . SER D 2 48  ? 385.458 357.032 184.536 1.00 151.98 ? 48  SER D N     1 
ATOM   10382 C  CA    . SER D 2 48  ? 385.382 358.089 185.540 1.00 156.20 ? 48  SER D CA    1 
ATOM   10383 C  C     . SER D 2 48  ? 385.638 357.541 186.940 1.00 154.31 ? 48  SER D C     1 
ATOM   10384 O  O     . SER D 2 48  ? 386.236 358.217 187.785 1.00 156.43 ? 48  SER D O     1 
ATOM   10385 C  CB    . SER D 2 48  ? 384.010 358.763 185.464 1.00 154.97 ? 48  SER D CB    1 
ATOM   10386 O  OG    . SER D 2 48  ? 383.628 359.307 186.708 1.00 158.21 ? 48  SER D OG    1 
ATOM   10387 N  N     . PHE D 2 49  ? 385.187 356.316 187.198 1.00 135.38 ? 49  PHE D N     1 
ATOM   10388 C  CA    . PHE D 2 49  ? 385.429 355.669 188.483 1.00 131.39 ? 49  PHE D CA    1 
ATOM   10389 C  C     . PHE D 2 49  ? 386.902 355.325 188.659 1.00 129.21 ? 49  PHE D C     1 
ATOM   10390 O  O     . PHE D 2 49  ? 387.447 355.438 189.763 1.00 129.09 ? 49  PHE D O     1 
ATOM   10391 C  CB    . PHE D 2 49  ? 384.552 354.411 188.592 1.00 134.25 ? 49  PHE D CB    1 
ATOM   10392 C  CG    . PHE D 2 49  ? 385.230 353.241 189.232 1.00 136.08 ? 49  PHE D CG    1 
ATOM   10393 C  CD1   . PHE D 2 49  ? 385.335 353.149 190.604 1.00 138.90 ? 49  PHE D CD1   1 
ATOM   10394 C  CD2   . PHE D 2 49  ? 385.752 352.218 188.452 1.00 131.76 ? 49  PHE D CD2   1 
ATOM   10395 C  CE1   . PHE D 2 49  ? 385.952 352.076 191.184 1.00 137.47 ? 49  PHE D CE1   1 
ATOM   10396 C  CE2   . PHE D 2 49  ? 386.378 351.139 189.035 1.00 129.86 ? 49  PHE D CE2   1 
ATOM   10397 C  CZ    . PHE D 2 49  ? 386.478 351.068 190.402 1.00 131.33 ? 49  PHE D CZ    1 
ATOM   10398 N  N     . ASN D 2 50  ? 387.557 354.886 187.583 1.00 121.35 ? 50  ASN D N     1 
ATOM   10399 C  CA    . ASN D 2 50  ? 388.908 354.342 187.695 1.00 120.77 ? 50  ASN D CA    1 
ATOM   10400 C  C     . ASN D 2 50  ? 389.944 355.369 188.145 1.00 120.25 ? 50  ASN D C     1 
ATOM   10401 O  O     . ASN D 2 50  ? 391.003 354.974 188.644 1.00 118.23 ? 50  ASN D O     1 
ATOM   10402 C  CB    . ASN D 2 50  ? 389.340 353.746 186.355 1.00 127.00 ? 50  ASN D CB    1 
ATOM   10403 C  CG    . ASN D 2 50  ? 390.618 352.938 186.462 1.00 127.67 ? 50  ASN D CG    1 
ATOM   10404 O  OD1   . ASN D 2 50  ? 390.589 351.745 186.762 1.00 131.19 ? 50  ASN D OD1   1 
ATOM   10405 N  ND2   . ASN D 2 50  ? 391.751 353.587 186.218 1.00 124.40 ? 50  ASN D ND2   1 
ATOM   10406 N  N     . THR D 2 51  ? 389.674 356.667 187.983 1.00 117.14 ? 51  THR D N     1 
ATOM   10407 C  CA    . THR D 2 51  ? 390.688 357.676 188.277 1.00 115.69 ? 51  THR D CA    1 
ATOM   10408 C  C     . THR D 2 51  ? 391.012 357.734 189.766 1.00 114.45 ? 51  THR D C     1 
ATOM   10409 O  O     . THR D 2 51  ? 392.183 357.666 190.157 1.00 116.64 ? 51  THR D O     1 
ATOM   10410 C  CB    . THR D 2 51  ? 390.219 359.044 187.782 1.00 113.28 ? 51  THR D CB    1 
ATOM   10411 O  OG1   . THR D 2 51  ? 390.013 358.998 186.365 1.00 113.95 ? 51  THR D OG1   1 
ATOM   10412 C  CG2   . THR D 2 51  ? 391.247 360.118 188.109 1.00 115.10 ? 51  THR D CG2   1 
ATOM   10413 N  N     . PHE D 2 52  ? 389.986 357.844 190.611 1.00 102.14 ? 52  PHE D N     1 
ATOM   10414 C  CA    . PHE D 2 52  ? 390.165 358.061 192.043 1.00 100.34 ? 52  PHE D CA    1 
ATOM   10415 C  C     . PHE D 2 52  ? 390.149 356.783 192.874 1.00 98.74  ? 52  PHE D C     1 
ATOM   10416 O  O     . PHE D 2 52  ? 390.426 356.854 194.076 1.00 100.61 ? 52  PHE D O     1 
ATOM   10417 C  CB    . PHE D 2 52  ? 389.079 359.008 192.569 1.00 100.85 ? 52  PHE D CB    1 
ATOM   10418 C  CG    . PHE D 2 52  ? 389.511 360.439 192.632 1.00 99.57  ? 52  PHE D CG    1 
ATOM   10419 C  CD1   . PHE D 2 52  ? 389.399 361.257 191.525 1.00 101.07 ? 52  PHE D CD1   1 
ATOM   10420 C  CD2   . PHE D 2 52  ? 390.031 360.968 193.799 1.00 103.96 ? 52  PHE D CD2   1 
ATOM   10421 C  CE1   . PHE D 2 52  ? 389.796 362.574 191.579 1.00 106.15 ? 52  PHE D CE1   1 
ATOM   10422 C  CE2   . PHE D 2 52  ? 390.430 362.285 193.859 1.00 106.45 ? 52  PHE D CE2   1 
ATOM   10423 C  CZ    . PHE D 2 52  ? 390.312 363.088 192.748 1.00 106.73 ? 52  PHE D CZ    1 
ATOM   10424 N  N     . PHE D 2 53  ? 389.848 355.629 192.274 1.00 99.83  ? 53  PHE D N     1 
ATOM   10425 C  CA    . PHE D 2 53  ? 389.683 354.369 192.985 1.00 100.18 ? 53  PHE D CA    1 
ATOM   10426 C  C     . PHE D 2 53  ? 390.555 353.287 192.367 1.00 110.12 ? 53  PHE D C     1 
ATOM   10427 O  O     . PHE D 2 53  ? 390.769 353.254 191.152 1.00 112.08 ? 53  PHE D O     1 
ATOM   10428 C  CB    . PHE D 2 53  ? 388.227 353.916 192.955 1.00 104.38 ? 53  PHE D CB    1 
ATOM   10429 C  CG    . PHE D 2 53  ? 387.297 354.798 193.732 1.00 107.93 ? 53  PHE D CG    1 
ATOM   10430 C  CD1   . PHE D 2 53  ? 386.742 355.922 193.150 1.00 105.31 ? 53  PHE D CD1   1 
ATOM   10431 C  CD2   . PHE D 2 53  ? 386.965 354.493 195.039 1.00 109.90 ? 53  PHE D CD2   1 
ATOM   10432 C  CE1   . PHE D 2 53  ? 385.882 356.731 193.861 1.00 106.13 ? 53  PHE D CE1   1 
ATOM   10433 C  CE2   . PHE D 2 53  ? 386.104 355.298 195.754 1.00 104.41 ? 53  PHE D CE2   1 
ATOM   10434 C  CZ    . PHE D 2 53  ? 385.562 356.418 195.164 1.00 104.96 ? 53  PHE D CZ    1 
ATOM   10435 N  N     . SER D 2 54  ? 391.049 352.400 193.227 1.00 126.66 ? 54  SER D N     1 
ATOM   10436 C  CA    . SER D 2 54  ? 391.769 351.197 192.837 1.00 122.72 ? 54  SER D CA    1 
ATOM   10437 C  C     . SER D 2 54  ? 390.800 350.027 192.913 1.00 120.25 ? 54  SER D C     1 
ATOM   10438 O  O     . SER D 2 54  ? 390.202 349.779 193.967 1.00 123.28 ? 54  SER D O     1 
ATOM   10439 C  CB    . SER D 2 54  ? 392.975 350.962 193.745 1.00 121.33 ? 54  SER D CB    1 
ATOM   10440 O  OG    . SER D 2 54  ? 393.646 349.763 193.399 1.00 118.77 ? 54  SER D OG    1 
ATOM   10441 N  N     . GLU D 2 55  ? 390.635 349.327 191.796 1.00 131.11 ? 55  GLU D N     1 
ATOM   10442 C  CA    . GLU D 2 55  ? 389.713 348.206 191.723 1.00 130.46 ? 55  GLU D CA    1 
ATOM   10443 C  C     . GLU D 2 55  ? 390.403 346.915 192.142 1.00 128.90 ? 55  GLU D C     1 
ATOM   10444 O  O     . GLU D 2 55  ? 391.592 346.709 191.879 1.00 129.82 ? 55  GLU D O     1 
ATOM   10445 C  CB    . GLU D 2 55  ? 389.162 348.064 190.306 1.00 132.17 ? 55  GLU D CB    1 
ATOM   10446 C  CG    . GLU D 2 55  ? 388.095 346.999 190.163 1.00 131.52 ? 55  GLU D CG    1 
ATOM   10447 C  CD    . GLU D 2 55  ? 387.243 347.198 188.928 1.00 133.88 ? 55  GLU D CD    1 
ATOM   10448 O  OE1   . GLU D 2 55  ? 387.791 347.626 187.890 1.00 134.20 ? 55  GLU D OE1   1 
ATOM   10449 O  OE2   . GLU D 2 55  ? 386.025 346.931 188.994 1.00 132.76 ? 55  GLU D OE2   1 
ATOM   10450 N  N     . THR D 2 56  ? 389.638 346.046 192.800 1.00 132.11 ? 56  THR D N     1 
ATOM   10451 C  CA    . THR D 2 56  ? 390.082 344.725 193.219 1.00 134.49 ? 56  THR D CA    1 
ATOM   10452 C  C     . THR D 2 56  ? 389.309 343.666 192.445 1.00 139.12 ? 56  THR D C     1 
ATOM   10453 O  O     . THR D 2 56  ? 388.205 343.909 191.949 1.00 139.85 ? 56  THR D O     1 
ATOM   10454 C  CB    . THR D 2 56  ? 389.882 344.513 194.725 1.00 131.44 ? 56  THR D CB    1 
ATOM   10455 O  OG1   . THR D 2 56  ? 388.482 344.476 195.023 1.00 136.75 ? 56  THR D OG1   1 
ATOM   10456 C  CG2   . THR D 2 56  ? 390.540 345.631 195.517 1.00 132.96 ? 56  THR D CG2   1 
ATOM   10457 N  N     . GLY D 2 57  ? 389.908 342.477 192.347 1.00 153.56 ? 57  GLY D N     1 
ATOM   10458 C  CA    . GLY D 2 57  ? 389.293 341.388 191.607 1.00 151.47 ? 57  GLY D CA    1 
ATOM   10459 C  C     . GLY D 2 57  ? 387.975 340.912 192.181 1.00 153.05 ? 57  GLY D C     1 
ATOM   10460 O  O     . GLY D 2 57  ? 387.154 340.360 191.441 1.00 155.10 ? 57  GLY D O     1 
ATOM   10461 N  N     . ALA D 2 58  ? 387.749 341.116 193.478 1.00 138.04 ? 58  ALA D N     1 
ATOM   10462 C  CA    . ALA D 2 58  ? 386.509 340.705 194.123 1.00 137.37 ? 58  ALA D CA    1 
ATOM   10463 C  C     . ALA D 2 58  ? 385.343 341.654 193.862 1.00 138.65 ? 58  ALA D C     1 
ATOM   10464 O  O     . ALA D 2 58  ? 384.243 341.394 194.363 1.00 138.67 ? 58  ALA D O     1 
ATOM   10465 C  CB    . ALA D 2 58  ? 386.729 340.575 195.632 1.00 135.88 ? 58  ALA D CB    1 
ATOM   10466 N  N     . GLY D 2 59  ? 385.546 342.740 193.107 1.00 126.99 ? 59  GLY D N     1 
ATOM   10467 C  CA    . GLY D 2 59  ? 384.516 343.725 192.858 1.00 121.76 ? 59  GLY D CA    1 
ATOM   10468 C  C     . GLY D 2 59  ? 384.515 344.898 193.814 1.00 125.08 ? 59  GLY D C     1 
ATOM   10469 O  O     . GLY D 2 59  ? 383.891 345.922 193.508 1.00 126.17 ? 59  GLY D O     1 
ATOM   10470 N  N     . LYS D 2 60  ? 385.189 344.788 194.954 1.00 125.36 ? 60  LYS D N     1 
ATOM   10471 C  CA    . LYS D 2 60  ? 385.322 345.921 195.856 1.00 120.65 ? 60  LYS D CA    1 
ATOM   10472 C  C     . LYS D 2 60  ? 386.228 346.977 195.238 1.00 116.15 ? 60  LYS D C     1 
ATOM   10473 O  O     . LYS D 2 60  ? 387.101 346.674 194.420 1.00 126.05 ? 60  LYS D O     1 
ATOM   10474 C  CB    . LYS D 2 60  ? 385.888 345.470 197.202 1.00 122.03 ? 60  LYS D CB    1 
ATOM   10475 C  CG    . LYS D 2 60  ? 385.694 346.480 198.328 1.00 120.46 ? 60  LYS D CG    1 
ATOM   10476 C  CD    . LYS D 2 60  ? 386.181 345.953 199.680 1.00 122.17 ? 60  LYS D CD    1 
ATOM   10477 C  CE    . LYS D 2 60  ? 385.278 344.877 200.289 1.00 126.97 ? 60  LYS D CE    1 
ATOM   10478 N  NZ    . LYS D 2 60  ? 383.863 345.308 200.471 1.00 125.22 ? 60  LYS D NZ    1 
ATOM   10479 N  N     . HIS D 2 61  ? 386.003 348.229 195.635 1.00 108.08 ? 61  HIS D N     1 
ATOM   10480 C  CA    . HIS D 2 61  ? 386.779 349.372 195.172 1.00 112.86 ? 61  HIS D CA    1 
ATOM   10481 C  C     . HIS D 2 61  ? 387.334 350.115 196.376 1.00 114.73 ? 61  HIS D C     1 
ATOM   10482 O  O     . HIS D 2 61  ? 386.580 350.457 197.292 1.00 112.47 ? 61  HIS D O     1 
ATOM   10483 C  CB    . HIS D 2 61  ? 385.919 350.306 194.328 1.00 106.65 ? 61  HIS D CB    1 
ATOM   10484 C  CG    . HIS D 2 61  ? 385.086 349.596 193.308 1.00 107.87 ? 61  HIS D CG    1 
ATOM   10485 N  ND1   . HIS D 2 61  ? 385.622 348.722 192.388 1.00 114.25 ? 61  HIS D ND1   1 
ATOM   10486 C  CD2   . HIS D 2 61  ? 383.757 349.641 193.054 1.00 112.31 ? 61  HIS D CD2   1 
ATOM   10487 C  CE1   . HIS D 2 61  ? 384.659 348.254 191.614 1.00 116.05 ? 61  HIS D CE1   1 
ATOM   10488 N  NE2   . HIS D 2 61  ? 383.517 348.795 191.998 1.00 115.82 ? 61  HIS D NE2   1 
ATOM   10489 N  N     . VAL D 2 62  ? 388.634 350.368 196.362 1.00 102.95 ? 62  VAL D N     1 
ATOM   10490 C  CA    . VAL D 2 62  ? 389.348 351.016 197.461 1.00 94.95  ? 62  VAL D CA    1 
ATOM   10491 C  C     . VAL D 2 62  ? 389.647 352.451 197.038 1.00 98.03  ? 62  VAL D C     1 
ATOM   10492 O  O     . VAL D 2 62  ? 390.068 352.665 195.898 1.00 101.60 ? 62  VAL D O     1 
ATOM   10493 C  CB    . VAL D 2 62  ? 390.653 350.274 197.807 1.00 99.48  ? 62  VAL D CB    1 
ATOM   10494 C  CG1   . VAL D 2 62  ? 391.410 351.020 198.898 1.00 109.58 ? 62  VAL D CG1   1 
ATOM   10495 C  CG2   . VAL D 2 62  ? 390.356 348.833 198.229 1.00 98.34  ? 62  VAL D CG2   1 
ATOM   10496 N  N     . PRO D 2 63  ? 389.438 353.460 197.889 1.00 100.37 ? 63  PRO D N     1 
ATOM   10497 C  CA    . PRO D 2 63  ? 389.891 354.804 197.519 1.00 96.69  ? 63  PRO D CA    1 
ATOM   10498 C  C     . PRO D 2 63  ? 391.405 354.888 197.438 1.00 102.53 ? 63  PRO D C     1 
ATOM   10499 O  O     . PRO D 2 63  ? 392.130 354.206 198.165 1.00 101.86 ? 63  PRO D O     1 
ATOM   10500 C  CB    . PRO D 2 63  ? 389.351 355.687 198.649 1.00 92.11  ? 63  PRO D CB    1 
ATOM   10501 C  CG    . PRO D 2 63  ? 388.230 354.945 199.199 1.00 96.97  ? 63  PRO D CG    1 
ATOM   10502 C  CD    . PRO D 2 63  ? 388.631 353.515 199.120 1.00 105.78 ? 63  PRO D CD    1 
ATOM   10503 N  N     . ARG D 2 64  ? 391.879 355.753 196.541 1.00 112.85 ? 64  ARG D N     1 
ATOM   10504 C  CA    . ARG D 2 64  ? 393.299 356.103 196.465 1.00 110.34 ? 64  ARG D CA    1 
ATOM   10505 C  C     . ARG D 2 64  ? 393.577 357.226 197.464 1.00 110.63 ? 64  ARG D C     1 
ATOM   10506 O  O     . ARG D 2 64  ? 393.917 358.355 197.107 1.00 119.52 ? 64  ARG D O     1 
ATOM   10507 C  CB    . ARG D 2 64  ? 393.674 356.515 195.048 1.00 109.48 ? 64  ARG D CB    1 
ATOM   10508 C  CG    . ARG D 2 64  ? 393.702 355.382 194.034 1.00 110.34 ? 64  ARG D CG    1 
ATOM   10509 C  CD    . ARG D 2 64  ? 394.580 355.732 192.839 1.00 107.02 ? 64  ARG D CD    1 
ATOM   10510 N  NE    . ARG D 2 64  ? 394.671 354.638 191.875 1.00 102.66 ? 64  ARG D NE    1 
ATOM   10511 C  CZ    . ARG D 2 64  ? 393.828 354.414 190.872 1.00 109.34 ? 64  ARG D CZ    1 
ATOM   10512 N  NH1   . ARG D 2 64  ? 392.769 355.182 190.656 1.00 116.27 ? 64  ARG D NH1   1 
ATOM   10513 N  NH2   . ARG D 2 64  ? 394.053 353.386 190.059 1.00 110.23 ? 64  ARG D NH2   1 
ATOM   10514 N  N     . ALA D 2 65  ? 393.429 356.880 198.745 1.00 104.25 ? 65  ALA D N     1 
ATOM   10515 C  CA    . ALA D 2 65  ? 393.415 357.838 199.841 1.00 105.46 ? 65  ALA D CA    1 
ATOM   10516 C  C     . ALA D 2 65  ? 394.436 357.450 200.897 1.00 108.43 ? 65  ALA D C     1 
ATOM   10517 O  O     . ALA D 2 65  ? 394.704 356.267 201.122 1.00 121.25 ? 65  ALA D O     1 
ATOM   10518 C  CB    . ALA D 2 65  ? 392.030 357.922 200.488 1.00 110.99 ? 65  ALA D CB    1 
ATOM   10519 N  N     . VAL D 2 66  ? 395.007 358.468 201.537 1.00 90.35  ? 66  VAL D N     1 
ATOM   10520 C  CA    . VAL D 2 66  ? 395.893 358.307 202.685 1.00 93.79  ? 66  VAL D CA    1 
ATOM   10521 C  C     . VAL D 2 66  ? 395.443 359.319 203.727 1.00 93.75  ? 66  VAL D C     1 
ATOM   10522 O  O     . VAL D 2 66  ? 395.623 360.528 203.539 1.00 96.27  ? 66  VAL D O     1 
ATOM   10523 C  CB    . VAL D 2 66  ? 397.372 358.513 202.324 1.00 92.32  ? 66  VAL D CB    1 
ATOM   10524 C  CG1   . VAL D 2 66  ? 398.273 358.055 203.471 1.00 94.78  ? 66  VAL D CG1   1 
ATOM   10525 C  CG2   . VAL D 2 66  ? 397.719 357.773 201.036 1.00 93.98  ? 66  VAL D CG2   1 
ATOM   10526 N  N     . PHE D 2 67  ? 394.861 358.831 204.820 1.00 101.48 ? 67  PHE D N     1 
ATOM   10527 C  CA    . PHE D 2 67  ? 394.389 359.667 205.916 1.00 97.14  ? 67  PHE D CA    1 
ATOM   10528 C  C     . PHE D 2 67  ? 395.432 359.633 207.023 1.00 101.74 ? 67  PHE D C     1 
ATOM   10529 O  O     . PHE D 2 67  ? 395.748 358.558 207.544 1.00 109.59 ? 67  PHE D O     1 
ATOM   10530 C  CB    . PHE D 2 67  ? 393.041 359.172 206.436 1.00 101.76 ? 67  PHE D CB    1 
ATOM   10531 C  CG    . PHE D 2 67  ? 391.868 359.637 205.623 1.00 99.40  ? 67  PHE D CG    1 
ATOM   10532 C  CD1   . PHE D 2 67  ? 391.732 359.259 204.300 1.00 101.84 ? 67  PHE D CD1   1 
ATOM   10533 C  CD2   . PHE D 2 67  ? 390.900 360.448 206.183 1.00 104.07 ? 67  PHE D CD2   1 
ATOM   10534 C  CE1   . PHE D 2 67  ? 390.655 359.684 203.553 1.00 102.35 ? 67  PHE D CE1   1 
ATOM   10535 C  CE2   . PHE D 2 67  ? 389.823 360.876 205.439 1.00 108.12 ? 67  PHE D CE2   1 
ATOM   10536 C  CZ    . PHE D 2 67  ? 389.700 360.494 204.123 1.00 102.72 ? 67  PHE D CZ    1 
ATOM   10537 N  N     . VAL D 2 68  ? 395.958 360.805 207.379 1.00 94.28  ? 68  VAL D N     1 
ATOM   10538 C  CA    . VAL D 2 68  ? 397.046 360.938 208.341 1.00 93.42  ? 68  VAL D CA    1 
ATOM   10539 C  C     . VAL D 2 68  ? 396.639 361.949 209.400 1.00 91.34  ? 68  VAL D C     1 
ATOM   10540 O  O     . VAL D 2 68  ? 396.118 363.021 209.077 1.00 96.59  ? 68  VAL D O     1 
ATOM   10541 C  CB    . VAL D 2 68  ? 398.361 361.372 207.666 1.00 93.53  ? 68  VAL D CB    1 
ATOM   10542 C  CG1   . VAL D 2 68  ? 399.531 361.235 208.643 1.00 99.98  ? 68  VAL D CG1   1 
ATOM   10543 C  CG2   . VAL D 2 68  ? 398.600 360.560 206.395 1.00 98.00  ? 68  VAL D CG2   1 
ATOM   10544 N  N     . ASP D 2 69  ? 396.869 361.600 210.662 1.00 101.44 ? 69  ASP D N     1 
ATOM   10545 C  CA    . ASP D 2 69  ? 396.689 362.531 211.763 1.00 109.70 ? 69  ASP D CA    1 
ATOM   10546 C  C     . ASP D 2 69  ? 397.461 361.999 212.957 1.00 109.42 ? 69  ASP D C     1 
ATOM   10547 O  O     . ASP D 2 69  ? 397.427 360.799 213.238 1.00 115.47 ? 69  ASP D O     1 
ATOM   10548 C  CB    . ASP D 2 69  ? 395.213 362.716 212.125 1.00 114.41 ? 69  ASP D CB    1 
ATOM   10549 C  CG    . ASP D 2 69  ? 394.952 364.019 212.850 1.00 114.52 ? 69  ASP D CG    1 
ATOM   10550 O  OD1   . ASP D 2 69  ? 395.888 364.542 213.490 1.00 116.25 ? 69  ASP D OD1   1 
ATOM   10551 O  OD2   . ASP D 2 69  ? 393.811 364.521 212.783 1.00 111.41 ? 69  ASP D OD2   1 
ATOM   10552 N  N     . LEU D 2 70  ? 398.152 362.896 213.654 1.00 106.93 ? 70  LEU D N     1 
ATOM   10553 C  CA    . LEU D 2 70  ? 398.964 362.493 214.791 1.00 105.42 ? 70  LEU D CA    1 
ATOM   10554 C  C     . LEU D 2 70  ? 398.127 362.195 216.028 1.00 108.58 ? 70  LEU D C     1 
ATOM   10555 O  O     . LEU D 2 70  ? 398.636 361.565 216.959 1.00 111.25 ? 70  LEU D O     1 
ATOM   10556 C  CB    . LEU D 2 70  ? 400.002 363.576 215.099 1.00 111.09 ? 70  LEU D CB    1 
ATOM   10557 C  CG    . LEU D 2 70  ? 400.899 364.015 213.935 1.00 111.05 ? 70  LEU D CG    1 
ATOM   10558 C  CD1   . LEU D 2 70  ? 401.787 365.166 214.360 1.00 110.98 ? 70  LEU D CD1   1 
ATOM   10559 C  CD2   . LEU D 2 70  ? 401.741 362.857 213.419 1.00 109.18 ? 70  LEU D CD2   1 
ATOM   10560 N  N     . GLU D 2 71  ? 396.809 362.654 216.061 1.00 128.92 ? 71  GLU D N     1 
ATOM   10561 C  CA    . GLU D 2 71  ? 395.846 362.226 217.064 1.00 127.76 ? 71  GLU D CA    1 
ATOM   10562 C  C     . GLU D 2 71  ? 394.972 361.108 216.497 1.00 128.93 ? 71  GLU D C     1 
ATOM   10563 O  O     . GLU D 2 71  ? 394.652 361.124 215.305 1.00 132.59 ? 71  GLU D O     1 
ATOM   10564 C  CB    . GLU D 2 71  ? 394.956 363.394 217.506 1.00 130.38 ? 71  GLU D CB    1 
ATOM   10565 C  CG    . GLU D 2 71  ? 393.899 363.810 216.489 1.00 134.74 ? 71  GLU D CG    1 
ATOM   10566 C  CD    . GLU D 2 71  ? 393.398 365.222 216.713 1.00 139.35 ? 71  GLU D CD    1 
ATOM   10567 O  OE1   . GLU D 2 71  ? 392.865 365.496 217.809 1.00 137.88 ? 71  GLU D OE1   1 
ATOM   10568 O  OE2   . GLU D 2 71  ? 393.540 366.060 215.797 1.00 142.52 ? 71  GLU D OE2   1 
ATOM   10569 N  N     . PRO D 2 72  ? 394.539 360.117 217.289 1.00 106.96 ? 72  PRO D N     1 
ATOM   10570 C  CA    . PRO D 2 72  ? 393.770 359.004 216.721 1.00 108.88 ? 72  PRO D CA    1 
ATOM   10571 C  C     . PRO D 2 72  ? 392.259 359.180 216.718 1.00 112.83 ? 72  PRO D C     1 
ATOM   10572 O  O     . PRO D 2 72  ? 391.574 358.350 216.107 1.00 120.48 ? 72  PRO D O     1 
ATOM   10573 C  CB    . PRO D 2 72  ? 394.162 357.844 217.641 1.00 108.53 ? 72  PRO D CB    1 
ATOM   10574 C  CG    . PRO D 2 72  ? 394.289 358.486 218.972 1.00 111.70 ? 72  PRO D CG    1 
ATOM   10575 C  CD    . PRO D 2 72  ? 394.735 359.916 218.739 1.00 106.77 ? 72  PRO D CD    1 
ATOM   10576 N  N     . THR D 2 73  ? 391.719 360.212 217.374 1.00 112.23 ? 73  THR D N     1 
ATOM   10577 C  CA    . THR D 2 73  ? 390.277 360.252 217.622 1.00 115.74 ? 73  THR D CA    1 
ATOM   10578 C  C     . THR D 2 73  ? 389.479 360.457 216.337 1.00 115.03 ? 73  THR D C     1 
ATOM   10579 O  O     . THR D 2 73  ? 388.471 359.777 216.116 1.00 126.43 ? 73  THR D O     1 
ATOM   10580 C  CB    . THR D 2 73  ? 389.926 361.332 218.658 1.00 122.06 ? 73  THR D CB    1 
ATOM   10581 O  OG1   . THR D 2 73  ? 388.511 361.330 218.880 1.00 126.10 ? 73  THR D OG1   1 
ATOM   10582 C  CG2   . THR D 2 73  ? 390.345 362.752 218.231 1.00 121.66 ? 73  THR D CG2   1 
ATOM   10583 N  N     . VAL D 2 74  ? 389.911 361.373 215.472 1.00 100.52 ? 74  VAL D N     1 
ATOM   10584 C  CA    . VAL D 2 74  ? 389.136 361.660 214.268 1.00 109.67 ? 74  VAL D CA    1 
ATOM   10585 C  C     . VAL D 2 74  ? 389.219 360.494 213.284 1.00 113.91 ? 74  VAL D C     1 
ATOM   10586 O  O     . VAL D 2 74  ? 388.221 360.121 212.649 1.00 118.10 ? 74  VAL D O     1 
ATOM   10587 C  CB    . VAL D 2 74  ? 389.595 362.999 213.650 1.00 109.98 ? 74  VAL D CB    1 
ATOM   10588 C  CG1   . VAL D 2 74  ? 391.059 362.959 213.165 1.00 116.95 ? 74  VAL D CG1   1 
ATOM   10589 C  CG2   . VAL D 2 74  ? 388.646 363.432 212.538 1.00 110.27 ? 74  VAL D CG2   1 
ATOM   10590 N  N     . ILE D 2 75  ? 390.399 359.889 213.148 1.00 111.91 ? 75  ILE D N     1 
ATOM   10591 C  CA    . ILE D 2 75  ? 390.528 358.746 212.254 1.00 109.20 ? 75  ILE D CA    1 
ATOM   10592 C  C     . ILE D 2 75  ? 389.763 357.551 212.812 1.00 112.72 ? 75  ILE D C     1 
ATOM   10593 O  O     . ILE D 2 75  ? 389.231 356.742 212.048 1.00 119.77 ? 75  ILE D O     1 
ATOM   10594 C  CB    . ILE D 2 75  ? 392.017 358.441 211.999 1.00 113.62 ? 75  ILE D CB    1 
ATOM   10595 C  CG1   . ILE D 2 75  ? 392.578 359.464 211.005 1.00 112.19 ? 75  ILE D CG1   1 
ATOM   10596 C  CG2   . ILE D 2 75  ? 392.220 357.029 211.443 1.00 112.66 ? 75  ILE D CG2   1 
ATOM   10597 C  CD1   . ILE D 2 75  ? 394.076 359.645 211.066 1.00 115.42 ? 75  ILE D CD1   1 
ATOM   10598 N  N     . ASP D 2 76  ? 389.686 357.415 214.136 1.00 117.16 ? 76  ASP D N     1 
ATOM   10599 C  CA    . ASP D 2 76  ? 388.837 356.375 214.708 1.00 113.74 ? 76  ASP D CA    1 
ATOM   10600 C  C     . ASP D 2 76  ? 387.362 356.669 214.464 1.00 114.82 ? 76  ASP D C     1 
ATOM   10601 O  O     . ASP D 2 76  ? 386.563 355.739 214.297 1.00 123.60 ? 76  ASP D O     1 
ATOM   10602 C  CB    . ASP D 2 76  ? 389.117 356.232 216.204 1.00 118.25 ? 76  ASP D CB    1 
ATOM   10603 C  CG    . ASP D 2 76  ? 390.453 355.559 216.493 1.00 123.24 ? 76  ASP D CG    1 
ATOM   10604 O  OD1   . ASP D 2 76  ? 391.109 355.061 215.553 1.00 121.66 ? 76  ASP D OD1   1 
ATOM   10605 O  OD2   . ASP D 2 76  ? 390.851 355.528 217.676 1.00 124.20 ? 76  ASP D OD2   1 
ATOM   10606 N  N     . GLU D 2 77  ? 386.986 357.949 214.436 1.00 111.48 ? 77  GLU D N     1 
ATOM   10607 C  CA    . GLU D 2 77  ? 385.631 358.311 214.023 1.00 109.21 ? 77  GLU D CA    1 
ATOM   10608 C  C     . GLU D 2 77  ? 385.362 357.846 212.599 1.00 105.45 ? 77  GLU D C     1 
ATOM   10609 O  O     . GLU D 2 77  ? 384.277 357.336 212.294 1.00 103.83 ? 77  GLU D O     1 
ATOM   10610 C  CB    . GLU D 2 77  ? 385.415 359.825 214.128 1.00 111.06 ? 77  GLU D CB    1 
ATOM   10611 C  CG    . GLU D 2 77  ? 384.434 360.249 215.208 1.00 112.26 ? 77  GLU D CG    1 
ATOM   10612 C  CD    . GLU D 2 77  ? 383.999 361.693 215.058 1.00 116.39 ? 77  GLU D CD    1 
ATOM   10613 O  OE1   . GLU D 2 77  ? 384.811 362.514 214.582 1.00 113.59 ? 77  GLU D OE1   1 
ATOM   10614 O  OE2   . GLU D 2 77  ? 382.843 362.007 215.408 1.00 114.62 ? 77  GLU D OE2   1 
ATOM   10615 N  N     . VAL D 2 78  ? 386.346 358.016 211.714 1.00 109.72 ? 78  VAL D N     1 
ATOM   10616 C  CA    . VAL D 2 78  ? 386.213 357.514 210.346 1.00 109.48 ? 78  VAL D CA    1 
ATOM   10617 C  C     . VAL D 2 78  ? 386.100 355.993 210.345 1.00 109.57 ? 78  VAL D C     1 
ATOM   10618 O  O     . VAL D 2 78  ? 385.279 355.417 209.621 1.00 114.92 ? 78  VAL D O     1 
ATOM   10619 C  CB    . VAL D 2 78  ? 387.393 357.993 209.478 1.00 116.48 ? 78  VAL D CB    1 
ATOM   10620 C  CG1   . VAL D 2 78  ? 387.333 357.351 208.092 1.00 113.78 ? 78  VAL D CG1   1 
ATOM   10621 C  CG2   . VAL D 2 78  ? 387.390 359.513 209.358 1.00 117.77 ? 78  VAL D CG2   1 
ATOM   10622 N  N     . ARG D 2 79  ? 386.922 355.321 211.152 1.00 106.06 ? 79  ARG D N     1 
ATOM   10623 C  CA    . ARG D 2 79  ? 386.908 353.864 211.241 1.00 104.43 ? 79  ARG D CA    1 
ATOM   10624 C  C     . ARG D 2 79  ? 385.627 353.311 211.848 1.00 110.54 ? 79  ARG D C     1 
ATOM   10625 O  O     . ARG D 2 79  ? 385.374 352.111 211.710 1.00 105.96 ? 79  ARG D O     1 
ATOM   10626 C  CB    . ARG D 2 79  ? 388.091 353.375 212.074 1.00 103.70 ? 79  ARG D CB    1 
ATOM   10627 C  CG    . ARG D 2 79  ? 389.443 353.524 211.408 1.00 103.69 ? 79  ARG D CG    1 
ATOM   10628 C  CD    . ARG D 2 79  ? 390.567 353.256 212.393 1.00 104.80 ? 79  ARG D CD    1 
ATOM   10629 N  NE    . ARG D 2 79  ? 391.882 353.448 211.791 1.00 104.69 ? 79  ARG D NE    1 
ATOM   10630 C  CZ    . ARG D 2 79  ? 393.011 353.682 212.453 1.00 108.88 ? 79  ARG D CZ    1 
ATOM   10631 N  NH1   . ARG D 2 79  ? 393.048 353.760 213.776 1.00 109.03 ? 79  ARG D NH1   1 
ATOM   10632 N  NH2   . ARG D 2 79  ? 394.139 353.840 211.768 1.00 115.19 ? 79  ARG D NH2   1 
ATOM   10633 N  N     . THR D 2 80  ? 384.854 354.133 212.559 1.00 125.98 ? 80  THR D N     1 
ATOM   10634 C  CA    . THR D 2 80  ? 383.536 353.751 213.054 1.00 117.83 ? 80  THR D CA    1 
ATOM   10635 C  C     . THR D 2 80  ? 382.393 354.234 212.167 1.00 114.16 ? 80  THR D C     1 
ATOM   10636 O  O     . THR D 2 80  ? 381.269 353.745 212.320 1.00 115.25 ? 80  THR D O     1 
ATOM   10637 C  CB    . THR D 2 80  ? 383.326 354.291 214.472 1.00 120.96 ? 80  THR D CB    1 
ATOM   10638 O  OG1   . THR D 2 80  ? 383.674 355.679 214.514 1.00 126.58 ? 80  THR D OG1   1 
ATOM   10639 C  CG2   . THR D 2 80  ? 384.184 353.526 215.465 1.00 118.38 ? 80  THR D CG2   1 
ATOM   10640 N  N     . GLY D 2 81  ? 382.641 355.165 211.251 1.00 113.46 ? 81  GLY D N     1 
ATOM   10641 C  CA    . GLY D 2 81  ? 381.583 355.709 210.430 1.00 117.73 ? 81  GLY D CA    1 
ATOM   10642 C  C     . GLY D 2 81  ? 381.071 354.710 209.405 1.00 119.29 ? 81  GLY D C     1 
ATOM   10643 O  O     . GLY D 2 81  ? 381.474 353.548 209.346 1.00 115.25 ? 81  GLY D O     1 
ATOM   10644 N  N     . THR D 2 82  ? 380.145 355.198 208.575 1.00 114.95 ? 82  THR D N     1 
ATOM   10645 C  CA    . THR D 2 82  ? 379.520 354.343 207.570 1.00 110.32 ? 82  THR D CA    1 
ATOM   10646 C  C     . THR D 2 82  ? 380.511 353.893 206.505 1.00 110.67 ? 82  THR D C     1 
ATOM   10647 O  O     . THR D 2 82  ? 380.363 352.796 205.954 1.00 113.33 ? 82  THR D O     1 
ATOM   10648 C  CB    . THR D 2 82  ? 378.350 355.074 206.912 1.00 105.01 ? 82  THR D CB    1 
ATOM   10649 O  OG1   . THR D 2 82  ? 378.740 356.416 206.593 1.00 104.13 ? 82  THR D OG1   1 
ATOM   10650 C  CG2   . THR D 2 82  ? 377.146 355.105 207.838 1.00 103.91 ? 82  THR D CG2   1 
ATOM   10651 N  N     . TYR D 2 83  ? 381.522 354.713 206.207 1.00 107.07 ? 83  TYR D N     1 
ATOM   10652 C  CA    . TYR D 2 83  ? 382.522 354.404 205.192 1.00 106.83 ? 83  TYR D CA    1 
ATOM   10653 C  C     . TYR D 2 83  ? 383.729 353.663 205.762 1.00 105.60 ? 83  TYR D C     1 
ATOM   10654 O  O     . TYR D 2 83  ? 384.835 353.772 205.217 1.00 116.22 ? 83  TYR D O     1 
ATOM   10655 C  CB    . TYR D 2 83  ? 382.958 355.692 204.489 1.00 106.18 ? 83  TYR D CB    1 
ATOM   10656 C  CG    . TYR D 2 83  ? 381.838 356.366 203.733 1.00 104.60 ? 83  TYR D CG    1 
ATOM   10657 C  CD1   . TYR D 2 83  ? 381.445 355.905 202.485 1.00 107.15 ? 83  TYR D CD1   1 
ATOM   10658 C  CD2   . TYR D 2 83  ? 381.170 357.459 204.267 1.00 105.02 ? 83  TYR D CD2   1 
ATOM   10659 C  CE1   . TYR D 2 83  ? 380.422 356.514 201.787 1.00 109.45 ? 83  TYR D CE1   1 
ATOM   10660 C  CE2   . TYR D 2 83  ? 380.144 358.074 203.576 1.00 110.91 ? 83  TYR D CE2   1 
ATOM   10661 C  CZ    . TYR D 2 83  ? 379.774 357.597 202.338 1.00 113.25 ? 83  TYR D CZ    1 
ATOM   10662 O  OH    . TYR D 2 83  ? 378.753 358.206 201.646 1.00 115.41 ? 83  TYR D OH    1 
ATOM   10663 N  N     . ARG D 2 84  ? 383.551 352.907 206.849 1.00 102.28 ? 84  ARG D N     1 
ATOM   10664 C  CA    . ARG D 2 84  ? 384.659 352.113 207.369 1.00 111.68 ? 84  ARG D CA    1 
ATOM   10665 C  C     . ARG D 2 84  ? 385.049 351.003 206.404 1.00 109.77 ? 84  ARG D C     1 
ATOM   10666 O  O     . ARG D 2 84  ? 386.239 350.705 206.255 1.00 112.61 ? 84  ARG D O     1 
ATOM   10667 C  CB    . ARG D 2 84  ? 384.311 351.556 208.760 1.00 114.37 ? 84  ARG D CB    1 
ATOM   10668 C  CG    . ARG D 2 84  ? 383.877 350.079 208.860 1.00 112.20 ? 84  ARG D CG    1 
ATOM   10669 C  CD    . ARG D 2 84  ? 383.452 349.734 210.295 1.00 115.84 ? 84  ARG D CD    1 
ATOM   10670 N  NE    . ARG D 2 84  ? 382.161 350.281 210.706 1.00 120.90 ? 84  ARG D NE    1 
ATOM   10671 C  CZ    . ARG D 2 84  ? 380.984 350.018 210.149 1.00 120.93 ? 84  ARG D CZ    1 
ATOM   10672 N  NH1   . ARG D 2 84  ? 380.841 349.093 209.212 1.00 119.31 ? 84  ARG D NH1   1 
ATOM   10673 N  NH2   . ARG D 2 84  ? 379.909 350.676 210.573 1.00 117.87 ? 84  ARG D NH2   1 
ATOM   10674 N  N     . GLN D 2 85  ? 384.072 350.384 205.744 1.00 105.03 ? 85  GLN D N     1 
ATOM   10675 C  CA    . GLN D 2 85  ? 384.377 349.341 204.776 1.00 107.83 ? 85  GLN D CA    1 
ATOM   10676 C  C     . GLN D 2 85  ? 385.063 349.890 203.533 1.00 109.04 ? 85  GLN D C     1 
ATOM   10677 O  O     . GLN D 2 85  ? 385.781 349.146 202.859 1.00 113.29 ? 85  GLN D O     1 
ATOM   10678 C  CB    . GLN D 2 85  ? 383.092 348.617 204.376 1.00 111.27 ? 85  GLN D CB    1 
ATOM   10679 C  CG    . GLN D 2 85  ? 382.441 347.818 205.497 1.00 113.06 ? 85  GLN D CG    1 
ATOM   10680 C  CD    . GLN D 2 85  ? 383.243 346.594 205.893 1.00 113.54 ? 85  GLN D CD    1 
ATOM   10681 O  OE1   . GLN D 2 85  ? 383.724 346.493 207.022 1.00 110.44 ? 85  GLN D OE1   1 
ATOM   10682 N  NE2   . GLN D 2 85  ? 383.385 345.654 204.967 1.00 114.33 ? 85  GLN D NE2   1 
ATOM   10683 N  N     . LEU D 2 86  ? 384.860 351.171 203.218 1.00 99.95  ? 86  LEU D N     1 
ATOM   10684 C  CA    . LEU D 2 86  ? 385.365 351.723 201.967 1.00 96.57  ? 86  LEU D CA    1 
ATOM   10685 C  C     . LEU D 2 86  ? 386.887 351.796 201.965 1.00 102.28 ? 86  LEU D C     1 
ATOM   10686 O  O     . LEU D 2 86  ? 387.538 351.370 201.004 1.00 102.98 ? 86  LEU D O     1 
ATOM   10687 C  CB    . LEU D 2 86  ? 384.757 353.107 201.741 1.00 98.92  ? 86  LEU D CB    1 
ATOM   10688 C  CG    . LEU D 2 86  ? 384.957 353.757 200.371 1.00 100.70 ? 86  LEU D CG    1 
ATOM   10689 C  CD1   . LEU D 2 86  ? 384.142 353.044 199.302 1.00 107.17 ? 86  LEU D CD1   1 
ATOM   10690 C  CD2   . LEU D 2 86  ? 384.607 355.235 200.420 1.00 101.73 ? 86  LEU D CD2   1 
ATOM   10691 N  N     . PHE D 2 87  ? 387.474 352.320 203.037 1.00 104.43 ? 87  PHE D N     1 
ATOM   10692 C  CA    . PHE D 2 87  ? 388.898 352.617 203.052 1.00 98.82  ? 87  PHE D CA    1 
ATOM   10693 C  C     . PHE D 2 87  ? 389.727 351.379 203.367 1.00 99.54  ? 87  PHE D C     1 
ATOM   10694 O  O     . PHE D 2 87  ? 389.276 350.455 204.048 1.00 98.37  ? 87  PHE D O     1 
ATOM   10695 C  CB    . PHE D 2 87  ? 389.202 353.711 204.075 1.00 92.38  ? 87  PHE D CB    1 
ATOM   10696 C  CG    . PHE D 2 87  ? 388.688 355.063 203.682 1.00 91.16  ? 87  PHE D CG    1 
ATOM   10697 C  CD1   . PHE D 2 87  ? 389.315 355.794 202.690 1.00 98.02  ? 87  PHE D CD1   1 
ATOM   10698 C  CD2   . PHE D 2 87  ? 387.576 355.603 204.301 1.00 95.79  ? 87  PHE D CD2   1 
ATOM   10699 C  CE1   . PHE D 2 87  ? 388.843 357.035 202.323 1.00 102.40 ? 87  PHE D CE1   1 
ATOM   10700 C  CE2   . PHE D 2 87  ? 387.101 356.845 203.939 1.00 99.22  ? 87  PHE D CE2   1 
ATOM   10701 C  CZ    . PHE D 2 87  ? 387.736 357.562 202.948 1.00 103.00 ? 87  PHE D CZ    1 
ATOM   10702 N  N     . HIS D 2 88  ? 390.951 351.372 202.849 1.00 98.98  ? 88  HIS D N     1 
ATOM   10703 C  CA    . HIS D 2 88  ? 391.920 350.355 203.222 1.00 96.96  ? 88  HIS D CA    1 
ATOM   10704 C  C     . HIS D 2 88  ? 392.204 350.495 204.720 1.00 100.40 ? 88  HIS D C     1 
ATOM   10705 O  O     . HIS D 2 88  ? 392.403 351.624 205.188 1.00 107.53 ? 88  HIS D O     1 
ATOM   10706 C  CB    . HIS D 2 88  ? 393.204 350.544 202.414 1.00 100.69 ? 88  HIS D CB    1 
ATOM   10707 C  CG    . HIS D 2 88  ? 394.063 349.322 202.327 1.00 100.33 ? 88  HIS D CG    1 
ATOM   10708 N  ND1   . HIS D 2 88  ? 394.456 348.604 203.435 1.00 101.72 ? 88  HIS D ND1   1 
ATOM   10709 C  CD2   . HIS D 2 88  ? 394.619 348.700 201.261 1.00 103.04 ? 88  HIS D CD2   1 
ATOM   10710 C  CE1   . HIS D 2 88  ? 395.209 347.588 203.055 1.00 106.62 ? 88  HIS D CE1   1 
ATOM   10711 N  NE2   . HIS D 2 88  ? 395.323 347.623 201.740 1.00 109.12 ? 88  HIS D NE2   1 
ATOM   10712 N  N     . PRO D 2 89  ? 392.190 349.410 205.513 1.00 104.60 ? 89  PRO D N     1 
ATOM   10713 C  CA    . PRO D 2 89  ? 392.449 349.591 206.954 1.00 107.74 ? 89  PRO D CA    1 
ATOM   10714 C  C     . PRO D 2 89  ? 393.824 350.150 207.283 1.00 108.18 ? 89  PRO D C     1 
ATOM   10715 O  O     . PRO D 2 89  ? 393.962 350.865 208.284 1.00 109.96 ? 89  PRO D O     1 
ATOM   10716 C  CB    . PRO D 2 89  ? 392.269 348.177 207.525 1.00 110.31 ? 89  PRO D CB    1 
ATOM   10717 C  CG    . PRO D 2 89  ? 391.392 347.499 206.573 1.00 113.55 ? 89  PRO D CG    1 
ATOM   10718 C  CD    . PRO D 2 89  ? 391.798 348.012 205.236 1.00 108.97 ? 89  PRO D CD    1 
ATOM   10719 N  N     . GLU D 2 90  ? 394.844 349.858 206.475 1.00 121.18 ? 90  GLU D N     1 
ATOM   10720 C  CA    . GLU D 2 90  ? 396.187 350.328 206.799 1.00 120.87 ? 90  GLU D CA    1 
ATOM   10721 C  C     . GLU D 2 90  ? 396.332 351.811 206.479 1.00 116.33 ? 90  GLU D C     1 
ATOM   10722 O  O     . GLU D 2 90  ? 397.005 352.543 207.214 1.00 120.74 ? 90  GLU D O     1 
ATOM   10723 C  CB    . GLU D 2 90  ? 397.229 349.499 206.036 1.00 122.79 ? 90  GLU D CB    1 
ATOM   10724 C  CG    . GLU D 2 90  ? 397.355 348.006 206.441 1.00 127.08 ? 90  GLU D CG    1 
ATOM   10725 C  CD    . GLU D 2 90  ? 398.343 347.173 205.628 1.00 131.62 ? 90  GLU D CD    1 
ATOM   10726 O  OE1   . GLU D 2 90  ? 398.845 347.651 204.592 1.00 133.34 ? 90  GLU D OE1   1 
ATOM   10727 O  OE2   . GLU D 2 90  ? 398.622 346.028 206.040 1.00 130.52 ? 90  GLU D OE2   1 
ATOM   10728 N  N     . GLN D 2 91  ? 395.723 352.272 205.379 1.00 111.78 ? 91  GLN D N     1 
ATOM   10729 C  CA    . GLN D 2 91  ? 395.989 353.622 204.883 1.00 114.27 ? 91  GLN D CA    1 
ATOM   10730 C  C     . GLN D 2 91  ? 395.493 354.709 205.829 1.00 119.07 ? 91  GLN D C     1 
ATOM   10731 O  O     . GLN D 2 91  ? 395.910 355.864 205.695 1.00 122.36 ? 91  GLN D O     1 
ATOM   10732 C  CB    . GLN D 2 91  ? 395.363 353.808 203.495 1.00 113.99 ? 91  GLN D CB    1 
ATOM   10733 C  CG    . GLN D 2 91  ? 393.870 354.184 203.488 1.00 121.46 ? 91  GLN D CG    1 
ATOM   10734 C  CD    . GLN D 2 91  ? 393.112 353.899 202.174 1.00 127.49 ? 91  GLN D CD    1 
ATOM   10735 O  OE1   . GLN D 2 91  ? 391.882 353.881 202.182 1.00 127.98 ? 91  GLN D OE1   1 
ATOM   10736 N  NE2   . GLN D 2 91  ? 393.822 353.720 201.052 1.00 126.89 ? 91  GLN D NE2   1 
ATOM   10737 N  N     . LEU D 2 92  ? 394.601 354.380 206.760 1.00 112.38 ? 92  LEU D N     1 
ATOM   10738 C  CA    . LEU D 2 92  ? 394.239 355.282 207.851 1.00 108.28 ? 92  LEU D CA    1 
ATOM   10739 C  C     . LEU D 2 92  ? 395.363 355.216 208.879 1.00 113.65 ? 92  LEU D C     1 
ATOM   10740 O  O     . LEU D 2 92  ? 395.353 354.396 209.798 1.00 121.63 ? 92  LEU D O     1 
ATOM   10741 C  CB    . LEU D 2 92  ? 392.889 354.895 208.446 1.00 104.65 ? 92  LEU D CB    1 
ATOM   10742 C  CG    . LEU D 2 92  ? 391.744 354.627 207.465 1.00 105.81 ? 92  LEU D CG    1 
ATOM   10743 C  CD1   . LEU D 2 92  ? 390.501 354.197 208.219 1.00 105.71 ? 92  LEU D CD1   1 
ATOM   10744 C  CD2   . LEU D 2 92  ? 391.457 355.852 206.618 1.00 108.69 ? 92  LEU D CD2   1 
ATOM   10745 N  N     . ILE D 2 93  ? 396.352 356.090 208.712 1.00 112.94 ? 93  ILE D N     1 
ATOM   10746 C  CA    . ILE D 2 93  ? 397.571 356.088 209.518 1.00 111.70 ? 93  ILE D CA    1 
ATOM   10747 C  C     . ILE D 2 93  ? 397.365 357.062 210.669 1.00 113.64 ? 93  ILE D C     1 
ATOM   10748 O  O     . ILE D 2 93  ? 396.939 358.204 210.454 1.00 114.88 ? 93  ILE D O     1 
ATOM   10749 C  CB    . ILE D 2 93  ? 398.814 356.461 208.679 1.00 110.35 ? 93  ILE D CB    1 
ATOM   10750 C  CG1   . ILE D 2 93  ? 398.931 355.603 207.399 1.00 116.73 ? 93  ILE D CG1   1 
ATOM   10751 C  CG2   . ILE D 2 93  ? 400.099 356.276 209.512 1.00 114.71 ? 93  ILE D CG2   1 
ATOM   10752 C  CD1   . ILE D 2 93  ? 399.976 356.081 206.403 1.00 117.54 ? 93  ILE D CD1   1 
ATOM   10753 N  N     . THR D 2 94  ? 397.674 356.612 211.889 1.00 108.60 ? 94  THR D N     1 
ATOM   10754 C  CA    . THR D 2 94  ? 397.446 357.371 213.114 1.00 104.35 ? 94  THR D CA    1 
ATOM   10755 C  C     . THR D 2 94  ? 398.717 357.432 213.945 1.00 101.65 ? 94  THR D C     1 
ATOM   10756 O  O     . THR D 2 94  ? 399.371 356.410 214.172 1.00 100.67 ? 94  THR D O     1 
ATOM   10757 C  CB    . THR D 2 94  ? 396.334 356.745 213.962 1.00 108.36 ? 94  THR D CB    1 
ATOM   10758 O  OG1   . THR D 2 94  ? 396.535 355.329 214.049 1.00 112.87 ? 94  THR D OG1   1 
ATOM   10759 C  CG2   . THR D 2 94  ? 394.974 357.026 213.355 1.00 106.19 ? 94  THR D CG2   1 
ATOM   10760 N  N     . GLY D 2 95  ? 399.059 358.641 214.397 1.00 102.98 ? 95  GLY D N     1 
ATOM   10761 C  CA    . GLY D 2 95  ? 400.069 358.822 215.418 1.00 101.92 ? 95  GLY D CA    1 
ATOM   10762 C  C     . GLY D 2 95  ? 399.474 358.687 216.808 1.00 106.18 ? 95  GLY D C     1 
ATOM   10763 O  O     . GLY D 2 95  ? 398.267 358.519 216.983 1.00 110.00 ? 95  GLY D O     1 
ATOM   10764 N  N     . LYS D 2 96  ? 400.349 358.793 217.811 1.00 116.02 ? 96  LYS D N     1 
ATOM   10765 C  CA    . LYS D 2 96  ? 399.977 358.518 219.197 1.00 117.64 ? 96  LYS D CA    1 
ATOM   10766 C  C     . LYS D 2 96  ? 399.550 359.765 219.965 1.00 116.58 ? 96  LYS D C     1 
ATOM   10767 O  O     . LYS D 2 96  ? 398.758 359.651 220.908 1.00 115.58 ? 96  LYS D O     1 
ATOM   10768 C  CB    . LYS D 2 96  ? 401.149 357.850 219.938 1.00 117.14 ? 96  LYS D CB    1 
ATOM   10769 C  CG    . LYS D 2 96  ? 401.196 356.288 220.046 1.00 115.05 ? 96  LYS D CG    1 
ATOM   10770 C  CD    . LYS D 2 96  ? 399.865 355.506 220.170 1.00 120.32 ? 96  LYS D CD    1 
ATOM   10771 C  CE    . LYS D 2 96  ? 398.962 355.989 221.308 1.00 120.32 ? 96  LYS D CE    1 
ATOM   10772 N  NZ    . LYS D 2 96  ? 397.574 355.466 221.173 1.00 116.84 ? 96  LYS D NZ    1 
ATOM   10773 N  N     . GLU D 2 97  ? 400.056 360.946 219.601 1.00 119.86 ? 97  GLU D N     1 
ATOM   10774 C  CA    . GLU D 2 97  ? 399.757 362.176 220.326 1.00 118.87 ? 97  GLU D CA    1 
ATOM   10775 C  C     . GLU D 2 97  ? 399.621 363.341 219.356 1.00 120.94 ? 97  GLU D C     1 
ATOM   10776 O  O     . GLU D 2 97  ? 400.206 363.352 218.271 1.00 123.20 ? 97  GLU D O     1 
ATOM   10777 C  CB    . GLU D 2 97  ? 400.836 362.488 221.371 1.00 118.98 ? 97  GLU D CB    1 
ATOM   10778 C  CG    . GLU D 2 97  ? 400.344 363.355 222.519 1.00 124.04 ? 97  GLU D CG    1 
ATOM   10779 C  CD    . GLU D 2 97  ? 401.358 363.476 223.635 1.00 126.51 ? 97  GLU D CD    1 
ATOM   10780 O  OE1   . GLU D 2 97  ? 402.552 363.204 223.387 1.00 126.09 ? 97  GLU D OE1   1 
ATOM   10781 O  OE2   . GLU D 2 97  ? 400.963 363.839 224.763 1.00 124.85 ? 97  GLU D OE2   1 
ATOM   10782 N  N     . ASP D 2 98  ? 398.850 364.337 219.782 1.00 118.73 ? 98  ASP D N     1 
ATOM   10783 C  CA    . ASP D 2 98  ? 398.513 365.489 218.963 1.00 117.62 ? 98  ASP D CA    1 
ATOM   10784 C  C     . ASP D 2 98  ? 399.691 366.458 218.867 1.00 115.58 ? 98  ASP D C     1 
ATOM   10785 O  O     . ASP D 2 98  ? 400.594 366.467 219.707 1.00 117.72 ? 98  ASP D O     1 
ATOM   10786 C  CB    . ASP D 2 98  ? 397.292 366.201 219.549 1.00 126.94 ? 98  ASP D CB    1 
ATOM   10787 C  CG    . ASP D 2 98  ? 396.645 367.158 218.571 1.00 128.89 ? 98  ASP D CG    1 
ATOM   10788 O  OD1   . ASP D 2 98  ? 397.205 368.252 218.361 1.00 131.59 ? 98  ASP D OD1   1 
ATOM   10789 O  OD2   . ASP D 2 98  ? 395.579 366.821 218.018 1.00 130.67 ? 98  ASP D OD2   1 
ATOM   10790 N  N     . ALA D 2 99  ? 399.669 367.284 217.817 1.00 105.87 ? 99  ALA D N     1 
ATOM   10791 C  CA    . ALA D 2 99  ? 400.670 368.327 217.629 1.00 106.42 ? 99  ALA D CA    1 
ATOM   10792 C  C     . ALA D 2 99  ? 400.428 369.560 218.490 1.00 110.04 ? 99  ALA D C     1 
ATOM   10793 O  O     . ALA D 2 99  ? 401.321 370.408 218.574 1.00 117.10 ? 99  ALA D O     1 
ATOM   10794 C  CB    . ALA D 2 99  ? 400.718 368.756 216.163 1.00 105.31 ? 99  ALA D CB    1 
ATOM   10795 N  N     . ALA D 2 100 ? 399.249 369.696 219.101 1.00 100.66 ? 100 ALA D N     1 
ATOM   10796 C  CA    . ALA D 2 100 ? 398.971 370.764 220.064 1.00 100.39 ? 100 ALA D CA    1 
ATOM   10797 C  C     . ALA D 2 100 ? 399.076 372.150 219.430 1.00 100.50 ? 100 ALA D C     1 
ATOM   10798 O  O     . ALA D 2 100 ? 399.544 373.101 220.058 1.00 107.92 ? 100 ALA D O     1 
ATOM   10799 C  CB    . ALA D 2 100 ? 399.895 370.658 221.277 1.00 104.49 ? 100 ALA D CB    1 
ATOM   10800 N  N     . ASN D 2 101 ? 398.610 372.269 218.182 1.00 91.85  ? 101 ASN D N     1 
ATOM   10801 C  CA    . ASN D 2 101 ? 398.622 373.531 217.430 1.00 92.06  ? 101 ASN D CA    1 
ATOM   10802 C  C     . ASN D 2 101 ? 400.041 374.100 217.329 1.00 90.62  ? 101 ASN D C     1 
ATOM   10803 O  O     . ASN D 2 101 ? 400.247 375.314 217.291 1.00 98.13  ? 101 ASN D O     1 
ATOM   10804 C  CB    . ASN D 2 101 ? 397.645 374.555 218.044 1.00 100.09 ? 101 ASN D CB    1 
ATOM   10805 C  CG    . ASN D 2 101 ? 396.207 374.367 217.574 1.00 103.13 ? 101 ASN D CG    1 
ATOM   10806 O  OD1   . ASN D 2 101 ? 395.896 373.482 216.779 1.00 100.69 ? 101 ASN D OD1   1 
ATOM   10807 N  ND2   . ASN D 2 101 ? 395.322 375.226 218.063 1.00 102.87 ? 101 ASN D ND2   1 
ATOM   10808 N  N     . ASN D 2 102 ? 401.028 373.208 217.243 1.00 96.62  ? 102 ASN D N     1 
ATOM   10809 C  CA    . ASN D 2 102 ? 402.443 373.566 217.276 1.00 100.06 ? 102 ASN D CA    1 
ATOM   10810 C  C     . ASN D 2 102 ? 403.087 373.086 215.982 1.00 98.23  ? 102 ASN D C     1 
ATOM   10811 O  O     . ASN D 2 102 ? 403.268 371.876 215.779 1.00 101.36 ? 102 ASN D O     1 
ATOM   10812 C  CB    . ASN D 2 102 ? 403.123 372.960 218.501 1.00 95.14  ? 102 ASN D CB    1 
ATOM   10813 C  CG    . ASN D 2 102 ? 404.470 373.583 218.792 1.00 94.46  ? 102 ASN D CG    1 
ATOM   10814 O  OD1   . ASN D 2 102 ? 405.109 374.151 217.910 1.00 101.42 ? 102 ASN D OD1   1 
ATOM   10815 N  ND2   . ASN D 2 102 ? 404.910 373.478 220.039 1.00 97.94  ? 102 ASN D ND2   1 
ATOM   10816 N  N     . TYR D 2 103 ? 403.425 374.047 215.114 1.00 95.57  ? 103 TYR D N     1 
ATOM   10817 C  CA    . TYR D 2 103 ? 404.157 373.728 213.894 1.00 93.81  ? 103 TYR D CA    1 
ATOM   10818 C  C     . TYR D 2 103 ? 405.469 373.043 214.219 1.00 92.98  ? 103 TYR D C     1 
ATOM   10819 O  O     . TYR D 2 103 ? 405.874 372.113 213.518 1.00 101.43 ? 103 TYR D O     1 
ATOM   10820 C  CB    . TYR D 2 103 ? 404.419 374.998 213.075 1.00 96.05  ? 103 TYR D CB    1 
ATOM   10821 C  CG    . TYR D 2 103 ? 405.237 374.771 211.811 1.00 97.83  ? 103 TYR D CG    1 
ATOM   10822 C  CD1   . TYR D 2 103 ? 404.617 374.472 210.612 1.00 103.86 ? 103 TYR D CD1   1 
ATOM   10823 C  CD2   . TYR D 2 103 ? 406.628 374.885 211.814 1.00 95.32  ? 103 TYR D CD2   1 
ATOM   10824 C  CE1   . TYR D 2 103 ? 405.351 374.269 209.465 1.00 106.03 ? 103 TYR D CE1   1 
ATOM   10825 C  CE2   . TYR D 2 103 ? 407.364 374.669 210.681 1.00 94.54  ? 103 TYR D CE2   1 
ATOM   10826 C  CZ    . TYR D 2 103 ? 406.722 374.371 209.508 1.00 103.02 ? 103 TYR D CZ    1 
ATOM   10827 O  OH    . TYR D 2 103 ? 407.460 374.170 208.374 1.00 105.57 ? 103 TYR D OH    1 
ATOM   10828 N  N     . ALA D 2 104 ? 406.163 373.519 215.254 1.00 96.69  ? 104 ALA D N     1 
ATOM   10829 C  CA    . ALA D 2 104 ? 407.449 372.938 215.617 1.00 99.70  ? 104 ALA D CA    1 
ATOM   10830 C  C     . ALA D 2 104 ? 407.292 371.472 215.988 1.00 104.48 ? 104 ALA D C     1 
ATOM   10831 O  O     . ALA D 2 104 ? 408.025 370.615 215.485 1.00 109.23 ? 104 ALA D O     1 
ATOM   10832 C  CB    . ALA D 2 104 ? 408.061 373.722 216.774 1.00 105.21 ? 104 ALA D CB    1 
ATOM   10833 N  N     . ARG D 2 105 ? 406.292 371.166 216.821 1.00 108.10 ? 105 ARG D N     1 
ATOM   10834 C  CA    . ARG D 2 105 ? 406.045 369.788 217.230 1.00 103.69 ? 105 ARG D CA    1 
ATOM   10835 C  C     . ARG D 2 105 ? 405.727 368.910 216.028 1.00 103.95 ? 105 ARG D C     1 
ATOM   10836 O  O     . ARG D 2 105 ? 406.418 367.912 215.778 1.00 111.79 ? 105 ARG D O     1 
ATOM   10837 C  CB    . ARG D 2 105 ? 404.896 369.748 218.238 1.00 102.11 ? 105 ARG D CB    1 
ATOM   10838 C  CG    . ARG D 2 105 ? 404.728 368.439 218.983 1.00 106.22 ? 105 ARG D CG    1 
ATOM   10839 C  CD    . ARG D 2 105 ? 403.795 368.616 220.172 1.00 108.46 ? 105 ARG D CD    1 
ATOM   10840 N  NE    . ARG D 2 105 ? 403.174 367.362 220.585 1.00 112.48 ? 105 ARG D NE    1 
ATOM   10841 C  CZ    . ARG D 2 105 ? 403.740 366.432 221.346 1.00 113.08 ? 105 ARG D CZ    1 
ATOM   10842 N  NH1   . ARG D 2 105 ? 404.973 366.563 221.816 1.00 111.10 ? 105 ARG D NH1   1 
ATOM   10843 N  NH2   . ARG D 2 105 ? 403.049 365.336 221.646 1.00 118.37 ? 105 ARG D NH2   1 
ATOM   10844 N  N     . GLY D 2 106 ? 404.741 369.325 215.226 1.00 91.90  ? 106 GLY D N     1 
ATOM   10845 C  CA    . GLY D 2 106 ? 404.304 368.498 214.112 1.00 97.25  ? 106 GLY D CA    1 
ATOM   10846 C  C     . GLY D 2 106 ? 405.364 368.324 213.040 1.00 94.19  ? 106 GLY D C     1 
ATOM   10847 O  O     . GLY D 2 106 ? 405.516 367.237 212.477 1.00 94.23  ? 106 GLY D O     1 
ATOM   10848 N  N     . HIS D 2 107 ? 406.111 369.388 212.741 1.00 101.51 ? 107 HIS D N     1 
ATOM   10849 C  CA    . HIS D 2 107 ? 407.113 369.316 211.689 1.00 99.43  ? 107 HIS D CA    1 
ATOM   10850 C  C     . HIS D 2 107 ? 408.339 368.529 212.130 1.00 102.67 ? 107 HIS D C     1 
ATOM   10851 O  O     . HIS D 2 107 ? 408.826 367.675 211.381 1.00 104.89 ? 107 HIS D O     1 
ATOM   10852 C  CB    . HIS D 2 107 ? 407.512 370.728 211.260 1.00 104.84 ? 107 HIS D CB    1 
ATOM   10853 C  CG    . HIS D 2 107 ? 408.315 370.774 209.998 1.00 103.84 ? 107 HIS D CG    1 
ATOM   10854 N  ND1   . HIS D 2 107 ? 407.746 370.646 208.750 1.00 105.65 ? 107 HIS D ND1   1 
ATOM   10855 C  CD2   . HIS D 2 107 ? 409.640 370.955 209.791 1.00 104.16 ? 107 HIS D CD2   1 
ATOM   10856 C  CE1   . HIS D 2 107 ? 408.687 370.734 207.828 1.00 100.42 ? 107 HIS D CE1   1 
ATOM   10857 N  NE2   . HIS D 2 107 ? 409.846 370.923 208.433 1.00 102.18 ? 107 HIS D NE2   1 
ATOM   10858 N  N     . TYR D 2 108 ? 408.842 368.779 213.344 1.00 101.92 ? 108 TYR D N     1 
ATOM   10859 C  CA    . TYR D 2 108 ? 410.156 368.293 213.743 1.00 96.78  ? 108 TYR D CA    1 
ATOM   10860 C  C     . TYR D 2 108 ? 410.095 367.065 214.642 1.00 100.19 ? 108 TYR D C     1 
ATOM   10861 O  O     . TYR D 2 108 ? 410.764 366.072 214.346 1.00 109.04 ? 108 TYR D O     1 
ATOM   10862 C  CB    . TYR D 2 108 ? 410.929 369.418 214.442 1.00 96.32  ? 108 TYR D CB    1 
ATOM   10863 C  CG    . TYR D 2 108 ? 411.436 370.476 213.488 1.00 97.10  ? 108 TYR D CG    1 
ATOM   10864 C  CD1   . TYR D 2 108 ? 412.566 370.259 212.714 1.00 97.24  ? 108 TYR D CD1   1 
ATOM   10865 C  CD2   . TYR D 2 108 ? 410.775 371.689 213.355 1.00 97.29  ? 108 TYR D CD2   1 
ATOM   10866 C  CE1   . TYR D 2 108 ? 413.028 371.223 211.839 1.00 96.00  ? 108 TYR D CE1   1 
ATOM   10867 C  CE2   . TYR D 2 108 ? 411.229 372.659 212.484 1.00 99.39  ? 108 TYR D CE2   1 
ATOM   10868 C  CZ    . TYR D 2 108 ? 412.355 372.420 211.728 1.00 101.16 ? 108 TYR D CZ    1 
ATOM   10869 O  OH    . TYR D 2 108 ? 412.812 373.382 210.858 1.00 112.61 ? 108 TYR D OH    1 
ATOM   10870 N  N     . THR D 2 109 ? 409.302 367.086 215.719 1.00 104.07 ? 109 THR D N     1 
ATOM   10871 C  CA    . THR D 2 109 ? 409.444 366.075 216.767 1.00 108.35 ? 109 THR D CA    1 
ATOM   10872 C  C     . THR D 2 109 ? 408.533 364.874 216.544 1.00 107.98 ? 109 THR D C     1 
ATOM   10873 O  O     . THR D 2 109 ? 409.015 363.740 216.484 1.00 114.31 ? 109 THR D O     1 
ATOM   10874 C  CB    . THR D 2 109 ? 409.181 366.682 218.153 1.00 110.69 ? 109 THR D CB    1 
ATOM   10875 O  OG1   . THR D 2 109 ? 407.860 367.228 218.203 1.00 118.05 ? 109 THR D OG1   1 
ATOM   10876 C  CG2   . THR D 2 109 ? 410.190 367.779 218.455 1.00 114.54 ? 109 THR D CG2   1 
ATOM   10877 N  N     . ILE D 2 110 ? 407.223 365.102 216.427 1.00 105.63 ? 110 ILE D N     1 
ATOM   10878 C  CA    . ILE D 2 110 ? 406.265 364.000 216.372 1.00 105.53 ? 110 ILE D CA    1 
ATOM   10879 C  C     . ILE D 2 110 ? 406.099 363.490 214.944 1.00 105.67 ? 110 ILE D C     1 
ATOM   10880 O  O     . ILE D 2 110 ? 405.891 362.292 214.720 1.00 112.62 ? 110 ILE D O     1 
ATOM   10881 C  CB    . ILE D 2 110 ? 404.912 364.429 216.978 1.00 110.21 ? 110 ILE D CB    1 
ATOM   10882 C  CG1   . ILE D 2 110 ? 405.079 364.985 218.409 1.00 110.94 ? 110 ILE D CG1   1 
ATOM   10883 C  CG2   . ILE D 2 110 ? 403.923 363.257 216.964 1.00 114.64 ? 110 ILE D CG2   1 
ATOM   10884 C  CD1   . ILE D 2 110 ? 405.716 364.033 219.427 1.00 113.11 ? 110 ILE D CD1   1 
ATOM   10885 N  N     . GLY D 2 111 ? 406.161 364.386 213.958 1.00 105.90 ? 111 GLY D N     1 
ATOM   10886 C  CA    . GLY D 2 111 ? 405.974 363.973 212.576 1.00 111.10 ? 111 GLY D CA    1 
ATOM   10887 C  C     . GLY D 2 111 ? 407.082 363.093 212.034 1.00 117.35 ? 111 GLY D C     1 
ATOM   10888 O  O     . GLY D 2 111 ? 406.858 362.359 211.064 1.00 125.64 ? 111 GLY D O     1 
ATOM   10889 N  N     . LYS D 2 112 ? 408.275 363.163 212.627 1.00 122.36 ? 112 LYS D N     1 
ATOM   10890 C  CA    . LYS D 2 112 ? 409.422 362.439 212.090 1.00 119.34 ? 112 LYS D CA    1 
ATOM   10891 C  C     . LYS D 2 112 ? 409.329 360.934 212.332 1.00 125.90 ? 112 LYS D C     1 
ATOM   10892 O  O     . LYS D 2 112 ? 409.984 360.159 211.625 1.00 131.04 ? 112 LYS D O     1 
ATOM   10893 C  CB    . LYS D 2 112 ? 410.710 363.044 212.665 1.00 125.04 ? 112 LYS D CB    1 
ATOM   10894 C  CG    . LYS D 2 112 ? 411.294 362.374 213.917 1.00 127.98 ? 112 LYS D CG    1 
ATOM   10895 C  CD    . LYS D 2 112 ? 412.449 363.194 214.504 1.00 126.47 ? 112 LYS D CD    1 
ATOM   10896 C  CE    . LYS D 2 112 ? 412.523 363.099 216.027 1.00 125.56 ? 112 LYS D CE    1 
ATOM   10897 N  NZ    . LYS D 2 112 ? 412.466 361.716 216.587 1.00 126.27 ? 112 LYS D NZ    1 
ATOM   10898 N  N     . GLU D 2 113 ? 408.533 360.494 213.312 1.00 141.74 ? 113 GLU D N     1 
ATOM   10899 C  CA    . GLU D 2 113 ? 408.367 359.056 213.512 1.00 141.45 ? 113 GLU D CA    1 
ATOM   10900 C  C     . GLU D 2 113 ? 407.527 358.451 212.397 1.00 143.01 ? 113 GLU D C     1 
ATOM   10901 O  O     . GLU D 2 113 ? 407.854 357.377 211.876 1.00 142.92 ? 113 GLU D O     1 
ATOM   10902 C  CB    . GLU D 2 113 ? 407.727 358.719 214.871 1.00 140.89 ? 113 GLU D CB    1 
ATOM   10903 C  CG    . GLU D 2 113 ? 408.429 359.139 216.195 1.00 144.11 ? 113 GLU D CG    1 
ATOM   10904 C  CD    . GLU D 2 113 ? 408.650 360.618 216.381 1.00 150.03 ? 113 GLU D CD    1 
ATOM   10905 O  OE1   . GLU D 2 113 ? 408.355 361.381 215.444 1.00 152.81 ? 113 GLU D OE1   1 
ATOM   10906 O  OE2   . GLU D 2 113 ? 409.106 361.013 217.472 1.00 151.69 ? 113 GLU D OE2   1 
ATOM   10907 N  N     . ILE D 2 114 ? 406.458 359.146 212.000 1.00 117.78 ? 114 ILE D N     1 
ATOM   10908 C  CA    . ILE D 2 114 ? 405.407 358.584 211.163 1.00 118.26 ? 114 ILE D CA    1 
ATOM   10909 C  C     . ILE D 2 114 ? 405.520 359.010 209.700 1.00 116.61 ? 114 ILE D C     1 
ATOM   10910 O  O     . ILE D 2 114 ? 404.810 358.451 208.843 1.00 121.79 ? 114 ILE D O     1 
ATOM   10911 C  CB    . ILE D 2 114 ? 404.034 358.968 211.763 1.00 114.51 ? 114 ILE D CB    1 
ATOM   10912 C  CG1   . ILE D 2 114 ? 402.958 357.933 211.426 1.00 119.69 ? 114 ILE D CG1   1 
ATOM   10913 C  CG2   . ILE D 2 114 ? 403.591 360.373 211.325 1.00 111.94 ? 114 ILE D CG2   1 
ATOM   10914 C  CD1   . ILE D 2 114 ? 401.664 358.160 212.186 1.00 118.90 ? 114 ILE D CD1   1 
ATOM   10915 N  N     . ILE D 2 115 ? 406.391 359.978 209.385 1.00 112.81 ? 115 ILE D N     1 
ATOM   10916 C  CA    . ILE D 2 115 ? 406.546 360.409 207.999 1.00 114.81 ? 115 ILE D CA    1 
ATOM   10917 C  C     . ILE D 2 115 ? 407.081 359.274 207.135 1.00 120.04 ? 115 ILE D C     1 
ATOM   10918 O  O     . ILE D 2 115 ? 406.744 359.175 205.952 1.00 124.24 ? 115 ILE D O     1 
ATOM   10919 C  CB    . ILE D 2 115 ? 407.450 361.661 207.923 1.00 117.29 ? 115 ILE D CB    1 
ATOM   10920 C  CG1   . ILE D 2 115 ? 407.510 362.257 206.505 1.00 119.03 ? 115 ILE D CG1   1 
ATOM   10921 C  CG2   . ILE D 2 115 ? 408.886 361.352 208.366 1.00 118.84 ? 115 ILE D CG2   1 
ATOM   10922 C  CD1   . ILE D 2 115 ? 406.181 362.733 205.942 1.00 118.84 ? 115 ILE D CD1   1 
ATOM   10923 N  N     . ASP D 2 116 ? 407.932 358.412 207.698 1.00 129.14 ? 116 ASP D N     1 
ATOM   10924 C  CA    . ASP D 2 116 ? 408.471 357.303 206.915 1.00 129.91 ? 116 ASP D CA    1 
ATOM   10925 C  C     . ASP D 2 116 ? 407.372 356.328 206.509 1.00 130.43 ? 116 ASP D C     1 
ATOM   10926 O  O     . ASP D 2 116 ? 407.314 355.894 205.352 1.00 132.51 ? 116 ASP D O     1 
ATOM   10927 C  CB    . ASP D 2 116 ? 409.563 356.585 207.707 1.00 133.54 ? 116 ASP D CB    1 
ATOM   10928 C  CG    . ASP D 2 116 ? 410.826 357.411 207.834 1.00 134.85 ? 116 ASP D CG    1 
ATOM   10929 O  OD1   . ASP D 2 116 ? 410.970 358.401 207.086 1.00 137.47 ? 116 ASP D OD1   1 
ATOM   10930 O  OD2   . ASP D 2 116 ? 411.674 357.072 208.685 1.00 133.31 ? 116 ASP D OD2   1 
ATOM   10931 N  N     . LEU D 2 117 ? 406.479 355.990 207.443 1.00 129.49 ? 117 LEU D N     1 
ATOM   10932 C  CA    . LEU D 2 117 ? 405.356 355.115 207.117 1.00 129.98 ? 117 LEU D CA    1 
ATOM   10933 C  C     . LEU D 2 117 ? 404.433 355.767 206.096 1.00 129.48 ? 117 LEU D C     1 
ATOM   10934 O  O     . LEU D 2 117 ? 403.949 355.102 205.167 1.00 128.95 ? 117 LEU D O     1 
ATOM   10935 C  CB    . LEU D 2 117 ? 404.590 354.762 208.394 1.00 129.37 ? 117 LEU D CB    1 
ATOM   10936 C  CG    . LEU D 2 117 ? 403.327 353.899 208.286 1.00 129.15 ? 117 LEU D CG    1 
ATOM   10937 C  CD1   . LEU D 2 117 ? 403.620 352.562 207.622 1.00 130.96 ? 117 LEU D CD1   1 
ATOM   10938 C  CD2   . LEU D 2 117 ? 402.725 353.686 209.665 1.00 128.67 ? 117 LEU D CD2   1 
ATOM   10939 N  N     . VAL D 2 118 ? 404.179 357.071 206.251 1.00 122.16 ? 118 VAL D N     1 
ATOM   10940 C  CA    . VAL D 2 118 ? 403.305 357.773 205.313 1.00 120.16 ? 118 VAL D CA    1 
ATOM   10941 C  C     . VAL D 2 118 ? 403.912 357.776 203.914 1.00 121.42 ? 118 VAL D C     1 
ATOM   10942 O  O     . VAL D 2 118 ? 403.217 357.534 202.918 1.00 123.48 ? 118 VAL D O     1 
ATOM   10943 C  CB    . VAL D 2 118 ? 403.017 359.201 205.816 1.00 119.01 ? 118 VAL D CB    1 
ATOM   10944 C  CG1   . VAL D 2 118 ? 402.279 360.012 204.757 1.00 121.33 ? 118 VAL D CG1   1 
ATOM   10945 C  CG2   . VAL D 2 118 ? 402.178 359.161 207.090 1.00 117.11 ? 118 VAL D CG2   1 
ATOM   10946 N  N     . LEU D 2 119 ? 405.216 358.037 203.816 1.00 124.13 ? 119 LEU D N     1 
ATOM   10947 C  CA    . LEU D 2 119 ? 405.878 358.040 202.518 1.00 122.56 ? 119 LEU D CA    1 
ATOM   10948 C  C     . LEU D 2 119 ? 405.894 356.648 201.904 1.00 124.03 ? 119 LEU D C     1 
ATOM   10949 O  O     . LEU D 2 119 ? 405.749 356.504 200.686 1.00 125.77 ? 119 LEU D O     1 
ATOM   10950 C  CB    . LEU D 2 119 ? 407.299 358.579 202.657 1.00 121.96 ? 119 LEU D CB    1 
ATOM   10951 C  CG    . LEU D 2 119 ? 407.422 360.069 202.980 1.00 123.49 ? 119 LEU D CG    1 
ATOM   10952 C  CD1   . LEU D 2 119 ? 408.818 360.377 203.485 1.00 126.46 ? 119 LEU D CD1   1 
ATOM   10953 C  CD2   . LEU D 2 119 ? 407.098 360.925 201.769 1.00 122.34 ? 119 LEU D CD2   1 
ATOM   10954 N  N     . ASP D 2 120 ? 406.080 355.612 202.726 1.00 134.74 ? 120 ASP D N     1 
ATOM   10955 C  CA    . ASP D 2 120 ? 406.050 354.247 202.209 1.00 135.60 ? 120 ASP D CA    1 
ATOM   10956 C  C     . ASP D 2 120 ? 404.682 353.903 201.634 1.00 135.48 ? 120 ASP D C     1 
ATOM   10957 O  O     . ASP D 2 120 ? 404.586 353.305 200.553 1.00 136.56 ? 120 ASP D O     1 
ATOM   10958 C  CB    . ASP D 2 120 ? 406.425 353.259 203.313 1.00 137.30 ? 120 ASP D CB    1 
ATOM   10959 C  CG    . ASP D 2 120 ? 407.872 353.390 203.755 1.00 142.71 ? 120 ASP D CG    1 
ATOM   10960 O  OD1   . ASP D 2 120 ? 408.648 354.107 203.089 1.00 140.05 ? 120 ASP D OD1   1 
ATOM   10961 O  OD2   . ASP D 2 120 ? 408.235 352.769 204.776 1.00 145.60 ? 120 ASP D OD2   1 
ATOM   10962 N  N     . ARG D 2 121 ? 403.607 354.285 202.328 1.00 127.24 ? 121 ARG D N     1 
ATOM   10963 C  CA    . ARG D 2 121 ? 402.283 353.962 201.807 1.00 125.88 ? 121 ARG D CA    1 
ATOM   10964 C  C     . ARG D 2 121 ? 401.952 354.813 200.585 1.00 124.17 ? 121 ARG D C     1 
ATOM   10965 O  O     . ARG D 2 121 ? 401.260 354.338 199.678 1.00 124.54 ? 121 ARG D O     1 
ATOM   10966 C  CB    . ARG D 2 121 ? 401.238 354.087 202.926 1.00 120.21 ? 121 ARG D CB    1 
ATOM   10967 C  CG    . ARG D 2 121 ? 399.727 354.129 202.529 1.00 121.95 ? 121 ARG D CG    1 
ATOM   10968 C  CD    . ARG D 2 121 ? 399.091 352.751 202.211 1.00 125.24 ? 121 ARG D CD    1 
ATOM   10969 N  NE    . ARG D 2 121 ? 399.687 351.605 202.895 1.00 130.07 ? 121 ARG D NE    1 
ATOM   10970 C  CZ    . ARG D 2 121 ? 399.436 350.329 202.618 1.00 133.71 ? 121 ARG D CZ    1 
ATOM   10971 N  NH1   . ARG D 2 121 ? 398.567 349.969 201.683 1.00 131.34 ? 121 ARG D NH1   1 
ATOM   10972 N  NH2   . ARG D 2 121 ? 400.073 349.384 203.303 1.00 131.46 ? 121 ARG D NH2   1 
ATOM   10973 N  N     . ILE D 2 122 ? 402.451 356.049 200.519 1.00 113.40 ? 122 ILE D N     1 
ATOM   10974 C  CA    . ILE D 2 122 ? 402.265 356.842 199.306 1.00 106.18 ? 122 ILE D CA    1 
ATOM   10975 C  C     . ILE D 2 122 ? 403.022 356.212 198.143 1.00 108.02 ? 122 ILE D C     1 
ATOM   10976 O  O     . ILE D 2 122 ? 402.548 356.219 197.002 1.00 115.39 ? 122 ILE D O     1 
ATOM   10977 C  CB    . ILE D 2 122 ? 402.690 358.305 199.540 1.00 109.64 ? 122 ILE D CB    1 
ATOM   10978 C  CG1   . ILE D 2 122 ? 401.697 359.010 200.466 1.00 107.38 ? 122 ILE D CG1   1 
ATOM   10979 C  CG2   . ILE D 2 122 ? 402.771 359.079 198.220 1.00 113.94 ? 122 ILE D CG2   1 
ATOM   10980 C  CD1   . ILE D 2 122 ? 402.299 360.141 201.251 1.00 114.50 ? 122 ILE D CD1   1 
ATOM   10981 N  N     . ARG D 2 123 ? 404.209 355.663 198.411 1.00 116.45 ? 123 ARG D N     1 
ATOM   10982 C  CA    . ARG D 2 123 ? 404.955 354.949 197.379 1.00 117.18 ? 123 ARG D CA    1 
ATOM   10983 C  C     . ARG D 2 123 ? 404.182 353.736 196.884 1.00 120.43 ? 123 ARG D C     1 
ATOM   10984 O  O     . ARG D 2 123 ? 404.125 353.473 195.676 1.00 124.89 ? 123 ARG D O     1 
ATOM   10985 C  CB    . ARG D 2 123 ? 406.317 354.520 197.925 1.00 121.29 ? 123 ARG D CB    1 
ATOM   10986 C  CG    . ARG D 2 123 ? 407.401 354.352 196.871 1.00 123.18 ? 123 ARG D CG    1 
ATOM   10987 C  CD    . ARG D 2 123 ? 408.778 354.245 197.513 1.00 125.87 ? 123 ARG D CD    1 
ATOM   10988 N  NE    . ARG D 2 123 ? 409.210 355.533 198.060 1.00 129.37 ? 123 ARG D NE    1 
ATOM   10989 C  CZ    . ARG D 2 123 ? 409.571 355.798 199.315 1.00 126.59 ? 123 ARG D CZ    1 
ATOM   10990 N  NH1   . ARG D 2 123 ? 409.592 354.870 200.262 1.00 125.35 ? 123 ARG D NH1   1 
ATOM   10991 N  NH2   . ARG D 2 123 ? 409.921 357.041 199.632 1.00 120.62 ? 123 ARG D NH2   1 
ATOM   10992 N  N     . LYS D 2 124 ? 403.583 352.985 197.808 1.00 125.07 ? 124 LYS D N     1 
ATOM   10993 C  CA    . LYS D 2 124 ? 402.810 351.812 197.415 1.00 123.41 ? 124 LYS D CA    1 
ATOM   10994 C  C     . LYS D 2 124 ? 401.591 352.212 196.593 1.00 123.74 ? 124 LYS D C     1 
ATOM   10995 O  O     . LYS D 2 124 ? 401.241 351.535 195.619 1.00 128.21 ? 124 LYS D O     1 
ATOM   10996 C  CB    . LYS D 2 124 ? 402.392 351.022 198.654 1.00 124.26 ? 124 LYS D CB    1 
ATOM   10997 C  CG    . LYS D 2 124 ? 401.851 349.621 198.336 1.00 130.82 ? 124 LYS D CG    1 
ATOM   10998 C  CD    . LYS D 2 124 ? 401.375 348.830 199.565 1.00 131.44 ? 124 LYS D CD    1 
ATOM   10999 C  CE    . LYS D 2 124 ? 402.415 348.718 200.678 1.00 131.71 ? 124 LYS D CE    1 
ATOM   11000 N  NZ    . LYS D 2 124 ? 403.759 348.317 200.175 1.00 132.42 ? 124 LYS D NZ    1 
ATOM   11001 N  N     . LEU D 2 125 ? 400.927 353.305 196.976 1.00 119.28 ? 125 LEU D N     1 
ATOM   11002 C  CA    . LEU D 2 125 ? 399.806 353.804 196.183 1.00 118.93 ? 125 LEU D CA    1 
ATOM   11003 C  C     . LEU D 2 125 ? 400.260 354.237 194.795 1.00 117.81 ? 125 LEU D C     1 
ATOM   11004 O  O     . LEU D 2 125 ? 399.574 353.978 193.800 1.00 123.05 ? 125 LEU D O     1 
ATOM   11005 C  CB    . LEU D 2 125 ? 399.124 354.974 196.899 1.00 118.26 ? 125 LEU D CB    1 
ATOM   11006 C  CG    . LEU D 2 125 ? 397.909 354.695 197.794 1.00 113.27 ? 125 LEU D CG    1 
ATOM   11007 C  CD1   . LEU D 2 125 ? 396.639 354.580 196.964 1.00 115.92 ? 125 LEU D CD1   1 
ATOM   11008 C  CD2   . LEU D 2 125 ? 398.098 353.450 198.647 1.00 116.86 ? 125 LEU D CD2   1 
ATOM   11009 N  N     . ALA D 2 126 ? 401.412 354.904 194.706 1.00 121.52 ? 126 ALA D N     1 
ATOM   11010 C  CA    . ALA D 2 126 ? 401.893 355.380 193.415 1.00 119.32 ? 126 ALA D CA    1 
ATOM   11011 C  C     . ALA D 2 126 ? 402.329 354.235 192.511 1.00 121.02 ? 126 ALA D C     1 
ATOM   11012 O  O     . ALA D 2 126 ? 402.260 354.361 191.283 1.00 124.31 ? 126 ALA D O     1 
ATOM   11013 C  CB    . ALA D 2 126 ? 403.051 356.355 193.615 1.00 123.38 ? 126 ALA D CB    1 
ATOM   11014 N  N     . ASP D 2 127 ? 402.794 353.124 193.091 1.00 132.23 ? 127 ASP D N     1 
ATOM   11015 C  CA    . ASP D 2 127 ? 403.283 352.015 192.274 1.00 135.05 ? 127 ASP D CA    1 
ATOM   11016 C  C     . ASP D 2 127 ? 402.181 351.393 191.424 1.00 135.80 ? 127 ASP D C     1 
ATOM   11017 O  O     . ASP D 2 127 ? 402.450 350.949 190.302 1.00 134.95 ? 127 ASP D O     1 
ATOM   11018 C  CB    . ASP D 2 127 ? 403.917 350.946 193.164 1.00 137.49 ? 127 ASP D CB    1 
ATOM   11019 C  CG    . ASP D 2 127 ? 405.223 351.401 193.792 1.00 141.27 ? 127 ASP D CG    1 
ATOM   11020 O  OD1   . ASP D 2 127 ? 405.757 352.456 193.390 1.00 138.84 ? 127 ASP D OD1   1 
ATOM   11021 O  OD2   . ASP D 2 127 ? 405.719 350.696 194.696 1.00 141.84 ? 127 ASP D OD2   1 
ATOM   11022 N  N     . GLN D 2 128 ? 400.946 351.358 191.923 1.00 137.39 ? 128 GLN D N     1 
ATOM   11023 C  CA    . GLN D 2 128 ? 399.835 350.740 191.205 1.00 136.01 ? 128 GLN D CA    1 
ATOM   11024 C  C     . GLN D 2 128 ? 399.172 351.676 190.192 1.00 138.77 ? 128 GLN D C     1 
ATOM   11025 O  O     . GLN D 2 128 ? 398.151 351.298 189.608 1.00 139.29 ? 128 GLN D O     1 
ATOM   11026 C  CB    . GLN D 2 128 ? 398.794 350.181 192.202 1.00 135.07 ? 128 GLN D CB    1 
ATOM   11027 C  CG    . GLN D 2 128 ? 398.232 351.108 193.312 1.00 139.35 ? 128 GLN D CG    1 
ATOM   11028 C  CD    . GLN D 2 128 ? 397.315 352.225 192.831 1.00 143.90 ? 128 GLN D CD    1 
ATOM   11029 O  OE1   . GLN D 2 128 ? 396.721 352.152 191.757 1.00 142.90 ? 128 GLN D OE1   1 
ATOM   11030 N  NE2   . GLN D 2 128 ? 397.200 353.272 193.639 1.00 143.87 ? 128 GLN D NE2   1 
ATOM   11031 N  N     . CYS D 2 129 ? 399.733 352.863 189.953 1.00 142.15 ? 129 CYS D N     1 
ATOM   11032 C  CA    . CYS D 2 129 ? 399.185 353.828 189.007 1.00 139.88 ? 129 CYS D CA    1 
ATOM   11033 C  C     . CYS D 2 129 ? 399.913 353.711 187.676 1.00 141.29 ? 129 CYS D C     1 
ATOM   11034 O  O     . CYS D 2 129 ? 401.147 353.657 187.641 1.00 138.61 ? 129 CYS D O     1 
ATOM   11035 C  CB    . CYS D 2 129 ? 399.317 355.252 189.547 1.00 140.37 ? 129 CYS D CB    1 
ATOM   11036 S  SG    . CYS D 2 129 ? 398.163 355.656 190.872 1.00 151.52 ? 129 CYS D SG    1 
ATOM   11037 N  N     . THR D 2 130 ? 399.148 353.671 186.584 1.00 140.28 ? 130 THR D N     1 
ATOM   11038 C  CA    . THR D 2 130 ? 399.755 353.669 185.257 1.00 138.18 ? 130 THR D CA    1 
ATOM   11039 C  C     . THR D 2 130 ? 400.413 355.013 184.969 1.00 136.20 ? 130 THR D C     1 
ATOM   11040 O  O     . THR D 2 130 ? 401.626 355.087 184.737 1.00 140.02 ? 130 THR D O     1 
ATOM   11041 C  CB    . THR D 2 130 ? 398.698 353.341 184.199 1.00 137.95 ? 130 THR D CB    1 
ATOM   11042 O  OG1   . THR D 2 130 ? 398.026 352.126 184.552 1.00 138.65 ? 130 THR D OG1   1 
ATOM   11043 C  CG2   . THR D 2 130 ? 399.337 353.183 182.822 1.00 135.79 ? 130 THR D CG2   1 
ATOM   11044 N  N     . GLY D 2 131 ? 399.618 356.083 184.967 1.00 118.20 ? 131 GLY D N     1 
ATOM   11045 C  CA    . GLY D 2 131 ? 400.110 357.446 184.875 1.00 119.64 ? 131 GLY D CA    1 
ATOM   11046 C  C     . GLY D 2 131 ? 399.540 358.299 185.988 1.00 121.00 ? 131 GLY D C     1 
ATOM   11047 O  O     . GLY D 2 131 ? 398.332 358.546 186.028 1.00 126.12 ? 131 GLY D O     1 
ATOM   11048 N  N     . LEU D 2 132 ? 400.400 358.759 186.893 1.00 106.07 ? 132 LEU D N     1 
ATOM   11049 C  CA    . LEU D 2 132 ? 399.977 359.532 188.057 1.00 106.91 ? 132 LEU D CA    1 
ATOM   11050 C  C     . LEU D 2 132 ? 399.980 361.010 187.687 1.00 112.74 ? 132 LEU D C     1 
ATOM   11051 O  O     . LEU D 2 132 ? 401.038 361.587 187.417 1.00 114.95 ? 132 LEU D O     1 
ATOM   11052 C  CB    . LEU D 2 132 ? 400.897 359.252 189.243 1.00 110.04 ? 132 LEU D CB    1 
ATOM   11053 C  CG    . LEU D 2 132 ? 400.626 359.985 190.560 1.00 112.20 ? 132 LEU D CG    1 
ATOM   11054 C  CD1   . LEU D 2 132 ? 399.247 359.653 191.109 1.00 112.36 ? 132 LEU D CD1   1 
ATOM   11055 C  CD2   . LEU D 2 132 ? 401.701 359.635 191.574 1.00 112.82 ? 132 LEU D CD2   1 
ATOM   11056 N  N     . GLN D 2 133 ? 398.794 361.622 187.674 1.00 125.31 ? 133 GLN D N     1 
ATOM   11057 C  CA    . GLN D 2 133 ? 398.703 363.046 187.372 1.00 120.17 ? 133 GLN D CA    1 
ATOM   11058 C  C     . GLN D 2 133 ? 399.362 363.884 188.458 1.00 117.71 ? 133 GLN D C     1 
ATOM   11059 O  O     . GLN D 2 133 ? 400.060 364.859 188.160 1.00 123.17 ? 133 GLN D O     1 
ATOM   11060 C  CB    . GLN D 2 133 ? 397.241 363.459 187.200 1.00 120.30 ? 133 GLN D CB    1 
ATOM   11061 C  CG    . GLN D 2 133 ? 396.517 362.781 186.047 1.00 123.42 ? 133 GLN D CG    1 
ATOM   11062 C  CD    . GLN D 2 133 ? 397.042 363.210 184.691 1.00 128.36 ? 133 GLN D CD    1 
ATOM   11063 O  OE1   . GLN D 2 133 ? 396.724 364.295 184.205 1.00 127.86 ? 133 GLN D OE1   1 
ATOM   11064 N  NE2   . GLN D 2 133 ? 397.854 362.360 184.074 1.00 130.13 ? 133 GLN D NE2   1 
ATOM   11065 N  N     . GLY D 2 134 ? 399.154 363.524 189.720 1.00 103.38 ? 134 GLY D N     1 
ATOM   11066 C  CA    . GLY D 2 134 ? 399.723 364.295 190.808 1.00 107.80 ? 134 GLY D CA    1 
ATOM   11067 C  C     . GLY D 2 134 ? 399.090 363.917 192.131 1.00 98.36  ? 134 GLY D C     1 
ATOM   11068 O  O     . GLY D 2 134 ? 398.473 362.859 192.259 1.00 106.58 ? 134 GLY D O     1 
ATOM   11069 N  N     . PHE D 2 135 ? 399.253 364.812 193.106 1.00 89.84  ? 135 PHE D N     1 
ATOM   11070 C  CA    . PHE D 2 135 ? 398.794 364.617 194.474 1.00 91.57  ? 135 PHE D CA    1 
ATOM   11071 C  C     . PHE D 2 135 ? 397.831 365.729 194.863 1.00 101.33 ? 135 PHE D C     1 
ATOM   11072 O  O     . PHE D 2 135 ? 398.044 366.895 194.518 1.00 114.88 ? 135 PHE D O     1 
ATOM   11073 C  CB    . PHE D 2 135 ? 399.970 364.600 195.456 1.00 96.27  ? 135 PHE D CB    1 
ATOM   11074 C  CG    . PHE D 2 135 ? 400.970 363.513 195.191 1.00 100.53 ? 135 PHE D CG    1 
ATOM   11075 C  CD1   . PHE D 2 135 ? 402.009 363.707 194.298 1.00 102.00 ? 135 PHE D CD1   1 
ATOM   11076 C  CD2   . PHE D 2 135 ? 400.876 362.298 195.845 1.00 100.91 ? 135 PHE D CD2   1 
ATOM   11077 C  CE1   . PHE D 2 135 ? 402.929 362.708 194.057 1.00 102.58 ? 135 PHE D CE1   1 
ATOM   11078 C  CE2   . PHE D 2 135 ? 401.794 361.296 195.608 1.00 97.82  ? 135 PHE D CE2   1 
ATOM   11079 C  CZ    . PHE D 2 135 ? 402.821 361.501 194.714 1.00 98.92  ? 135 PHE D CZ    1 
ATOM   11080 N  N     . LEU D 2 136 ? 396.772 365.352 195.575 1.00 112.94 ? 136 LEU D N     1 
ATOM   11081 C  CA    . LEU D 2 136 ? 395.836 366.281 196.195 1.00 110.97 ? 136 LEU D CA    1 
ATOM   11082 C  C     . LEU D 2 136 ? 396.056 366.251 197.700 1.00 112.26 ? 136 LEU D C     1 
ATOM   11083 O  O     . LEU D 2 136 ? 396.141 365.170 198.291 1.00 120.45 ? 136 LEU D O     1 
ATOM   11084 C  CB    . LEU D 2 136 ? 394.390 365.911 195.860 1.00 112.20 ? 136 LEU D CB    1 
ATOM   11085 C  CG    . LEU D 2 136 ? 393.816 366.563 194.600 1.00 112.83 ? 136 LEU D CG    1 
ATOM   11086 C  CD1   . LEU D 2 136 ? 394.485 366.006 193.354 1.00 120.02 ? 136 LEU D CD1   1 
ATOM   11087 C  CD2   . LEU D 2 136 ? 392.312 366.365 194.534 1.00 112.83 ? 136 LEU D CD2   1 
ATOM   11088 N  N     . VAL D 2 137 ? 396.153 367.433 198.311 1.00 104.57 ? 137 VAL D N     1 
ATOM   11089 C  CA    . VAL D 2 137 ? 396.467 367.581 199.729 1.00 99.97  ? 137 VAL D CA    1 
ATOM   11090 C  C     . VAL D 2 137 ? 395.373 368.408 200.386 1.00 102.62 ? 137 VAL D C     1 
ATOM   11091 O  O     . VAL D 2 137 ? 394.919 369.412 199.826 1.00 105.82 ? 137 VAL D O     1 
ATOM   11092 C  CB    . VAL D 2 137 ? 397.851 368.229 199.945 1.00 101.36 ? 137 VAL D CB    1 
ATOM   11093 C  CG1   . VAL D 2 137 ? 398.252 368.168 201.423 1.00 102.88 ? 137 VAL D CG1   1 
ATOM   11094 C  CG2   . VAL D 2 137 ? 398.893 367.542 199.069 1.00 102.66 ? 137 VAL D CG2   1 
ATOM   11095 N  N     . PHE D 2 138 ? 394.944 367.972 201.570 1.00 108.18 ? 138 PHE D N     1 
ATOM   11096 C  CA    . PHE D 2 138 ? 393.901 368.630 202.348 1.00 106.24 ? 138 PHE D CA    1 
ATOM   11097 C  C     . PHE D 2 138 ? 394.418 368.843 203.760 1.00 108.75 ? 138 PHE D C     1 
ATOM   11098 O  O     . PHE D 2 138 ? 394.869 367.893 204.407 1.00 113.89 ? 138 PHE D O     1 
ATOM   11099 C  CB    . PHE D 2 138 ? 392.621 367.793 202.380 1.00 106.27 ? 138 PHE D CB    1 
ATOM   11100 C  CG    . PHE D 2 138 ? 391.932 367.688 201.054 1.00 107.76 ? 138 PHE D CG    1 
ATOM   11101 C  CD1   . PHE D 2 138 ? 392.367 366.780 200.104 1.00 107.22 ? 138 PHE D CD1   1 
ATOM   11102 C  CD2   . PHE D 2 138 ? 390.850 368.495 200.755 1.00 108.73 ? 138 PHE D CD2   1 
ATOM   11103 C  CE1   . PHE D 2 138 ? 391.739 366.679 198.885 1.00 106.98 ? 138 PHE D CE1   1 
ATOM   11104 C  CE2   . PHE D 2 138 ? 390.219 368.396 199.535 1.00 107.63 ? 138 PHE D CE2   1 
ATOM   11105 C  CZ    . PHE D 2 138 ? 390.665 367.486 198.600 1.00 106.80 ? 138 PHE D CZ    1 
ATOM   11106 N  N     . HIS D 2 139 ? 394.346 370.078 204.236 1.00 96.29  ? 139 HIS D N     1 
ATOM   11107 C  CA    . HIS D 2 139 ? 394.848 370.426 205.560 1.00 100.95 ? 139 HIS D CA    1 
ATOM   11108 C  C     . HIS D 2 139 ? 394.323 371.812 205.908 1.00 100.94 ? 139 HIS D C     1 
ATOM   11109 O  O     . HIS D 2 139 ? 393.549 372.411 205.155 1.00 102.50 ? 139 HIS D O     1 
ATOM   11110 C  CB    . HIS D 2 139 ? 396.375 370.388 205.603 1.00 99.44  ? 139 HIS D CB    1 
ATOM   11111 C  CG    . HIS D 2 139 ? 397.022 371.387 204.696 1.00 96.22  ? 139 HIS D CG    1 
ATOM   11112 N  ND1   . HIS D 2 139 ? 397.350 371.101 203.390 1.00 96.65  ? 139 HIS D ND1   1 
ATOM   11113 C  CD2   . HIS D 2 139 ? 397.380 372.677 204.900 1.00 94.86  ? 139 HIS D CD2   1 
ATOM   11114 C  CE1   . HIS D 2 139 ? 397.899 372.165 202.833 1.00 98.06  ? 139 HIS D CE1   1 
ATOM   11115 N  NE2   . HIS D 2 139 ? 397.928 373.136 203.728 1.00 96.48  ? 139 HIS D NE2   1 
ATOM   11116 N  N     . SER D 2 140 ? 394.760 372.317 207.060 1.00 102.48 ? 140 SER D N     1 
ATOM   11117 C  CA    . SER D 2 140 ? 394.473 373.670 207.511 1.00 101.58 ? 140 SER D CA    1 
ATOM   11118 C  C     . SER D 2 140 ? 395.764 374.312 207.993 1.00 102.10 ? 140 SER D C     1 
ATOM   11119 O  O     . SER D 2 140 ? 396.581 373.662 208.650 1.00 108.58 ? 140 SER D O     1 
ATOM   11120 C  CB    . SER D 2 140 ? 393.431 373.675 208.635 1.00 105.42 ? 140 SER D CB    1 
ATOM   11121 O  OG    . SER D 2 140 ? 394.025 373.362 209.881 1.00 111.58 ? 140 SER D OG    1 
ATOM   11122 N  N     . PHE D 2 141 ? 395.945 375.589 207.651 1.00 98.89  ? 141 PHE D N     1 
ATOM   11123 C  CA    . PHE D 2 141 ? 397.119 376.324 208.113 1.00 103.06 ? 141 PHE D CA    1 
ATOM   11124 C  C     . PHE D 2 141 ? 397.133 376.450 209.630 1.00 103.43 ? 141 PHE D C     1 
ATOM   11125 O  O     . PHE D 2 141 ? 398.197 376.361 210.253 1.00 100.75 ? 141 PHE D O     1 
ATOM   11126 C  CB    . PHE D 2 141 ? 397.149 377.721 207.478 1.00 110.15 ? 141 PHE D CB    1 
ATOM   11127 C  CG    . PHE D 2 141 ? 397.383 377.750 205.972 1.00 105.72 ? 141 PHE D CG    1 
ATOM   11128 C  CD1   . PHE D 2 141 ? 397.924 376.677 205.273 1.00 104.50 ? 141 PHE D CD1   1 
ATOM   11129 C  CD2   . PHE D 2 141 ? 397.046 378.887 205.259 1.00 104.42 ? 141 PHE D CD2   1 
ATOM   11130 C  CE1   . PHE D 2 141 ? 398.131 376.751 203.912 1.00 105.49 ? 141 PHE D CE1   1 
ATOM   11131 C  CE2   . PHE D 2 141 ? 397.243 378.957 203.896 1.00 101.30 ? 141 PHE D CE2   1 
ATOM   11132 C  CZ    . PHE D 2 141 ? 397.782 377.888 203.223 1.00 101.18 ? 141 PHE D CZ    1 
ATOM   11133 N  N     . GLY D 2 142 ? 395.968 376.671 210.239 1.00 107.80 ? 142 GLY D N     1 
ATOM   11134 C  CA    . GLY D 2 142 ? 395.921 376.897 211.672 1.00 106.80 ? 142 GLY D CA    1 
ATOM   11135 C  C     . GLY D 2 142 ? 396.336 375.695 212.494 1.00 105.98 ? 142 GLY D C     1 
ATOM   11136 O  O     . GLY D 2 142 ? 396.997 375.846 213.526 1.00 110.79 ? 142 GLY D O     1 
ATOM   11137 N  N     . GLY D 2 143 ? 395.959 374.496 212.060 1.00 112.07 ? 143 GLY D N     1 
ATOM   11138 C  CA    . GLY D 2 143 ? 396.278 373.307 212.818 1.00 112.97 ? 143 GLY D CA    1 
ATOM   11139 C  C     . GLY D 2 143 ? 397.765 373.022 212.861 1.00 110.21 ? 143 GLY D C     1 
ATOM   11140 O  O     . GLY D 2 143 ? 398.504 373.234 211.901 1.00 111.16 ? 143 GLY D O     1 
ATOM   11141 N  N     . GLY D 2 144 ? 398.205 372.506 214.004 1.00 107.30 ? 144 GLY D N     1 
ATOM   11142 C  CA    . GLY D 2 144 ? 399.601 372.169 214.185 1.00 104.55 ? 144 GLY D CA    1 
ATOM   11143 C  C     . GLY D 2 144 ? 399.998 370.965 213.362 1.00 96.94  ? 144 GLY D C     1 
ATOM   11144 O  O     . GLY D 2 144 ? 401.013 370.994 212.658 1.00 93.52  ? 144 GLY D O     1 
ATOM   11145 N  N     . THR D 2 145 ? 399.191 369.902 213.442 1.00 110.88 ? 145 THR D N     1 
ATOM   11146 C  CA    . THR D 2 145 ? 399.428 368.716 212.627 1.00 112.62 ? 145 THR D CA    1 
ATOM   11147 C  C     . THR D 2 145 ? 399.368 369.059 211.151 1.00 103.03 ? 145 THR D C     1 
ATOM   11148 O  O     . THR D 2 145 ? 400.267 368.695 210.388 1.00 108.60 ? 145 THR D O     1 
ATOM   11149 C  CB    . THR D 2 145 ? 398.406 367.625 212.952 1.00 115.69 ? 145 THR D CB    1 
ATOM   11150 O  OG1   . THR D 2 145 ? 398.542 367.220 214.319 1.00 125.29 ? 145 THR D OG1   1 
ATOM   11151 C  CG2   . THR D 2 145 ? 398.594 366.421 212.040 1.00 107.03 ? 145 THR D CG2   1 
ATOM   11152 N  N     . GLY D 2 146 ? 398.324 369.785 210.740 1.00 106.17 ? 146 GLY D N     1 
ATOM   11153 C  CA    . GLY D 2 146 ? 398.188 370.156 209.341 1.00 108.29 ? 146 GLY D CA    1 
ATOM   11154 C  C     . GLY D 2 146 ? 399.364 370.968 208.840 1.00 111.10 ? 146 GLY D C     1 
ATOM   11155 O  O     . GLY D 2 146 ? 400.024 370.583 207.878 1.00 119.22 ? 146 GLY D O     1 
ATOM   11156 N  N     . SER D 2 147 ? 399.701 372.042 209.558 1.00 114.36 ? 147 SER D N     1 
ATOM   11157 C  CA    . SER D 2 147 ? 400.809 372.915 209.179 1.00 111.95 ? 147 SER D CA    1 
ATOM   11158 C  C     . SER D 2 147 ? 402.136 372.157 209.119 1.00 106.63 ? 147 SER D C     1 
ATOM   11159 O  O     . SER D 2 147 ? 402.763 372.056 208.053 1.00 106.90 ? 147 SER D O     1 
ATOM   11160 C  CB    . SER D 2 147 ? 400.885 374.070 210.179 1.00 113.28 ? 147 SER D CB    1 
ATOM   11161 O  OG    . SER D 2 147 ? 401.057 373.584 211.497 1.00 124.78 ? 147 SER D OG    1 
ATOM   11162 N  N     . GLY D 2 148 ? 402.563 371.592 210.253 1.00 104.68 ? 148 GLY D N     1 
ATOM   11163 C  CA    . GLY D 2 148 ? 403.868 370.953 210.304 1.00 104.53 ? 148 GLY D CA    1 
ATOM   11164 C  C     . GLY D 2 148 ? 403.974 369.744 209.395 1.00 100.42 ? 148 GLY D C     1 
ATOM   11165 O  O     . GLY D 2 148 ? 404.945 369.599 208.643 1.00 106.97 ? 148 GLY D O     1 
ATOM   11166 N  N     . PHE D 2 149 ? 402.971 368.863 209.436 1.00 101.30 ? 149 PHE D N     1 
ATOM   11167 C  CA    . PHE D 2 149 ? 403.078 367.638 208.667 1.00 101.92 ? 149 PHE D CA    1 
ATOM   11168 C  C     . PHE D 2 149 ? 402.908 367.890 207.178 1.00 102.79 ? 149 PHE D C     1 
ATOM   11169 O  O     . PHE D 2 149 ? 403.553 367.215 206.376 1.00 113.29 ? 149 PHE D O     1 
ATOM   11170 C  CB    . PHE D 2 149 ? 402.067 366.600 209.136 1.00 104.56 ? 149 PHE D CB    1 
ATOM   11171 C  CG    . PHE D 2 149 ? 402.468 365.206 208.782 1.00 102.62 ? 149 PHE D CG    1 
ATOM   11172 C  CD1   . PHE D 2 149 ? 401.923 364.577 207.680 1.00 104.80 ? 149 PHE D CD1   1 
ATOM   11173 C  CD2   . PHE D 2 149 ? 403.414 364.532 209.534 1.00 97.97  ? 149 PHE D CD2   1 
ATOM   11174 C  CE1   . PHE D 2 149 ? 402.308 363.303 207.339 1.00 109.34 ? 149 PHE D CE1   1 
ATOM   11175 C  CE2   . PHE D 2 149 ? 403.798 363.255 209.200 1.00 101.97 ? 149 PHE D CE2   1 
ATOM   11176 C  CZ    . PHE D 2 149 ? 403.245 362.640 208.103 1.00 107.96 ? 149 PHE D CZ    1 
ATOM   11177 N  N     . THR D 2 150 ? 402.048 368.833 206.767 1.00 103.21 ? 150 THR D N     1 
ATOM   11178 C  CA    . THR D 2 150 ? 401.968 369.108 205.340 1.00 107.66 ? 150 THR D CA    1 
ATOM   11179 C  C     . THR D 2 150 ? 403.240 369.776 204.846 1.00 112.48 ? 150 THR D C     1 
ATOM   11180 O  O     . THR D 2 150 ? 403.649 369.527 203.714 1.00 112.22 ? 150 THR D O     1 
ATOM   11181 C  CB    . THR D 2 150 ? 400.728 369.944 204.993 1.00 115.31 ? 150 THR D CB    1 
ATOM   11182 O  OG1   . THR D 2 150 ? 400.366 369.700 203.628 1.00 115.23 ? 150 THR D OG1   1 
ATOM   11183 C  CG2   . THR D 2 150 ? 400.949 371.449 205.173 1.00 121.40 ? 150 THR D CG2   1 
ATOM   11184 N  N     . SER D 2 151 ? 403.909 370.577 205.682 1.00 114.91 ? 151 SER D N     1 
ATOM   11185 C  CA    . SER D 2 151 ? 405.202 371.124 205.277 1.00 112.26 ? 151 SER D CA    1 
ATOM   11186 C  C     . SER D 2 151 ? 406.226 370.012 205.073 1.00 110.80 ? 151 SER D C     1 
ATOM   11187 O  O     . SER D 2 151 ? 406.896 369.944 204.028 1.00 111.56 ? 151 SER D O     1 
ATOM   11188 C  CB    . SER D 2 151 ? 405.689 372.118 206.325 1.00 114.19 ? 151 SER D CB    1 
ATOM   11189 O  OG    . SER D 2 151 ? 404.804 373.216 206.417 1.00 119.10 ? 151 SER D OG    1 
ATOM   11190 N  N     . LEU D 2 152 ? 406.339 369.118 206.060 1.00 106.51 ? 152 LEU D N     1 
ATOM   11191 C  CA    . LEU D 2 152 ? 407.289 368.012 205.978 1.00 99.21  ? 152 LEU D CA    1 
ATOM   11192 C  C     . LEU D 2 152 ? 406.969 367.105 204.792 1.00 99.62  ? 152 LEU D C     1 
ATOM   11193 O  O     . LEU D 2 152 ? 407.857 366.729 204.015 1.00 109.30 ? 152 LEU D O     1 
ATOM   11194 C  CB    . LEU D 2 152 ? 407.259 367.230 207.294 1.00 99.16  ? 152 LEU D CB    1 
ATOM   11195 C  CG    . LEU D 2 152 ? 408.134 365.987 207.457 1.00 98.02  ? 152 LEU D CG    1 
ATOM   11196 C  CD1   . LEU D 2 152 ? 409.603 366.356 207.418 1.00 101.94 ? 152 LEU D CD1   1 
ATOM   11197 C  CD2   . LEU D 2 152 ? 407.795 365.287 208.760 1.00 108.78 ? 152 LEU D CD2   1 
ATOM   11198 N  N     . LEU D 2 153 ? 405.691 366.771 204.626 1.00 102.01 ? 153 LEU D N     1 
ATOM   11199 C  CA    . LEU D 2 153 ? 405.261 365.885 203.556 1.00 105.94 ? 153 LEU D CA    1 
ATOM   11200 C  C     . LEU D 2 153 ? 405.474 366.523 202.191 1.00 107.84 ? 153 LEU D C     1 
ATOM   11201 O  O     . LEU D 2 153 ? 405.869 365.841 201.243 1.00 111.64 ? 153 LEU D O     1 
ATOM   11202 C  CB    . LEU D 2 153 ? 403.791 365.525 203.769 1.00 104.91 ? 153 LEU D CB    1 
ATOM   11203 C  CG    . LEU D 2 153 ? 403.101 364.572 202.793 1.00 99.82  ? 153 LEU D CG    1 
ATOM   11204 C  CD1   . LEU D 2 153 ? 403.618 363.163 202.986 1.00 105.38 ? 153 LEU D CD1   1 
ATOM   11205 C  CD2   . LEU D 2 153 ? 401.598 364.620 202.980 1.00 104.41 ? 153 LEU D CD2   1 
ATOM   11206 N  N     . MET D 2 154 ? 405.198 367.823 202.064 1.00 109.97 ? 154 MET D N     1 
ATOM   11207 C  CA    . MET D 2 154 ? 405.407 368.505 200.794 1.00 108.92 ? 154 MET D CA    1 
ATOM   11208 C  C     . MET D 2 154 ? 406.875 368.525 200.408 1.00 111.03 ? 154 MET D C     1 
ATOM   11209 O  O     . MET D 2 154 ? 407.208 368.276 199.244 1.00 116.09 ? 154 MET D O     1 
ATOM   11210 C  CB    . MET D 2 154 ? 404.847 369.924 200.863 1.00 110.13 ? 154 MET D CB    1 
ATOM   11211 C  CG    . MET D 2 154 ? 403.315 369.981 200.763 1.00 109.45 ? 154 MET D CG    1 
ATOM   11212 S  SD    . MET D 2 154 ? 402.513 369.795 199.140 1.00 115.17 ? 154 MET D SD    1 
ATOM   11213 C  CE    . MET D 2 154 ? 403.819 370.033 197.934 1.00 114.59 ? 154 MET D CE    1 
ATOM   11214 N  N     . GLU D 2 155 ? 407.774 368.805 201.359 1.00 115.64 ? 155 GLU D N     1 
ATOM   11215 C  CA    . GLU D 2 155 ? 409.189 368.794 200.993 1.00 116.96 ? 155 GLU D CA    1 
ATOM   11216 C  C     . GLU D 2 155 ? 409.654 367.383 200.641 1.00 114.45 ? 155 GLU D C     1 
ATOM   11217 O  O     . GLU D 2 155 ? 410.411 367.198 199.678 1.00 116.73 ? 155 GLU D O     1 
ATOM   11218 C  CB    . GLU D 2 155 ? 410.052 369.412 202.100 1.00 117.12 ? 155 GLU D CB    1 
ATOM   11219 C  CG    . GLU D 2 155 ? 410.034 368.727 203.451 1.00 119.69 ? 155 GLU D CG    1 
ATOM   11220 C  CD    . GLU D 2 155 ? 411.096 369.270 204.385 1.00 122.63 ? 155 GLU D CD    1 
ATOM   11221 O  OE1   . GLU D 2 155 ? 411.262 370.506 204.444 1.00 124.65 ? 155 GLU D OE1   1 
ATOM   11222 O  OE2   . GLU D 2 155 ? 411.768 368.460 205.058 1.00 119.44 ? 155 GLU D OE2   1 
ATOM   11223 N  N     . ARG D 2 156 ? 409.179 366.369 201.374 1.00 113.28 ? 156 ARG D N     1 
ATOM   11224 C  CA    . ARG D 2 156 ? 409.581 364.998 201.064 1.00 110.64 ? 156 ARG D CA    1 
ATOM   11225 C  C     . ARG D 2 156 ? 409.055 364.556 199.701 1.00 109.30 ? 156 ARG D C     1 
ATOM   11226 O  O     . ARG D 2 156 ? 409.782 363.924 198.926 1.00 112.90 ? 156 ARG D O     1 
ATOM   11227 C  CB    . ARG D 2 156 ? 409.101 364.047 202.159 1.00 108.02 ? 156 ARG D CB    1 
ATOM   11228 C  CG    . ARG D 2 156 ? 409.794 364.238 203.505 1.00 111.02 ? 156 ARG D CG    1 
ATOM   11229 C  CD    . ARG D 2 156 ? 411.219 363.704 203.511 1.00 111.96 ? 156 ARG D CD    1 
ATOM   11230 N  NE    . ARG D 2 156 ? 411.791 363.723 204.858 1.00 114.84 ? 156 ARG D NE    1 
ATOM   11231 C  CZ    . ARG D 2 156 ? 411.839 362.704 205.711 1.00 116.83 ? 156 ARG D CZ    1 
ATOM   11232 N  NH1   . ARG D 2 156 ? 411.353 361.507 205.413 1.00 111.43 ? 156 ARG D NH1   1 
ATOM   11233 N  NH2   . ARG D 2 156 ? 412.387 362.891 206.908 1.00 118.34 ? 156 ARG D NH2   1 
ATOM   11234 N  N     . LEU D 2 157 ? 407.800 364.884 199.385 1.00 104.36 ? 157 LEU D N     1 
ATOM   11235 C  CA    . LEU D 2 157 ? 407.240 364.510 198.089 1.00 102.93 ? 157 LEU D CA    1 
ATOM   11236 C  C     . LEU D 2 157 ? 407.909 365.273 196.956 1.00 106.70 ? 157 LEU D C     1 
ATOM   11237 O  O     . LEU D 2 157 ? 408.089 364.728 195.863 1.00 114.45 ? 157 LEU D O     1 
ATOM   11238 C  CB    . LEU D 2 157 ? 405.730 364.755 198.060 1.00 102.84 ? 157 LEU D CB    1 
ATOM   11239 C  CG    . LEU D 2 157 ? 404.789 363.635 198.525 1.00 102.55 ? 157 LEU D CG    1 
ATOM   11240 C  CD1   . LEU D 2 157 ? 405.347 362.852 199.711 1.00 109.95 ? 157 LEU D CD1   1 
ATOM   11241 C  CD2   . LEU D 2 157 ? 403.411 364.202 198.843 1.00 107.84 ? 157 LEU D CD2   1 
ATOM   11242 N  N     . SER D 2 158 ? 408.263 366.539 197.181 1.00 115.37 ? 158 SER D N     1 
ATOM   11243 C  CA    . SER D 2 158 ? 408.974 367.286 196.152 1.00 120.58 ? 158 SER D CA    1 
ATOM   11244 C  C     . SER D 2 158 ? 410.350 366.686 195.902 1.00 122.19 ? 158 SER D C     1 
ATOM   11245 O  O     . SER D 2 158 ? 410.823 366.657 194.760 1.00 119.96 ? 158 SER D O     1 
ATOM   11246 C  CB    . SER D 2 158 ? 409.090 368.754 196.555 1.00 123.64 ? 158 SER D CB    1 
ATOM   11247 O  OG    . SER D 2 158 ? 409.655 369.520 195.506 1.00 123.99 ? 158 SER D OG    1 
ATOM   11248 N  N     . VAL D 2 159 ? 411.009 366.204 196.957 1.00 124.43 ? 159 VAL D N     1 
ATOM   11249 C  CA    . VAL D 2 159 ? 412.289 365.525 196.775 1.00 121.99 ? 159 VAL D CA    1 
ATOM   11250 C  C     . VAL D 2 159 ? 412.094 364.218 196.013 1.00 117.58 ? 159 VAL D C     1 
ATOM   11251 O  O     . VAL D 2 159 ? 412.871 363.888 195.110 1.00 120.35 ? 159 VAL D O     1 
ATOM   11252 C  CB    . VAL D 2 159 ? 412.969 365.298 198.141 1.00 121.67 ? 159 VAL D CB    1 
ATOM   11253 C  CG1   . VAL D 2 159 ? 414.136 364.313 198.030 1.00 116.18 ? 159 VAL D CG1   1 
ATOM   11254 C  CG2   . VAL D 2 159 ? 413.460 366.622 198.716 1.00 119.03 ? 159 VAL D CG2   1 
ATOM   11255 N  N     . ASP D 2 160 ? 411.056 363.455 196.362 1.00 112.63 ? 160 ASP D N     1 
ATOM   11256 C  CA    . ASP D 2 160 ? 410.902 362.111 195.811 1.00 114.03 ? 160 ASP D CA    1 
ATOM   11257 C  C     . ASP D 2 160 ? 410.360 362.136 194.384 1.00 111.51 ? 160 ASP D C     1 
ATOM   11258 O  O     . ASP D 2 160 ? 411.034 361.700 193.445 1.00 114.29 ? 160 ASP D O     1 
ATOM   11259 C  CB    . ASP D 2 160 ? 409.982 361.282 196.711 1.00 115.91 ? 160 ASP D CB    1 
ATOM   11260 C  CG    . ASP D 2 160 ? 410.690 360.762 197.946 1.00 120.55 ? 160 ASP D CG    1 
ATOM   11261 O  OD1   . ASP D 2 160 ? 411.707 361.366 198.348 1.00 118.40 ? 160 ASP D OD1   1 
ATOM   11262 O  OD2   . ASP D 2 160 ? 410.231 359.750 198.515 1.00 117.56 ? 160 ASP D OD2   1 
ATOM   11263 N  N     . TYR D 2 161 ? 409.143 362.646 194.205 1.00 116.81 ? 161 TYR D N     1 
ATOM   11264 C  CA    . TYR D 2 161 ? 408.462 362.604 192.916 1.00 116.79 ? 161 TYR D CA    1 
ATOM   11265 C  C     . TYR D 2 161 ? 408.860 363.772 192.021 1.00 118.61 ? 161 TYR D C     1 
ATOM   11266 O  O     . TYR D 2 161 ? 409.301 363.564 190.887 1.00 118.21 ? 161 TYR D O     1 
ATOM   11267 C  CB    . TYR D 2 161 ? 406.949 362.594 193.135 1.00 115.83 ? 161 TYR D CB    1 
ATOM   11268 C  CG    . TYR D 2 161 ? 406.467 361.343 193.824 1.00 115.60 ? 161 TYR D CG    1 
ATOM   11269 C  CD1   . TYR D 2 161 ? 406.147 360.206 193.099 1.00 117.28 ? 161 TYR D CD1   1 
ATOM   11270 C  CD2   . TYR D 2 161 ? 406.348 361.294 195.205 1.00 119.95 ? 161 TYR D CD2   1 
ATOM   11271 C  CE1   . TYR D 2 161 ? 405.715 359.059 193.730 1.00 118.74 ? 161 TYR D CE1   1 
ATOM   11272 C  CE2   . TYR D 2 161 ? 405.916 360.154 195.843 1.00 119.89 ? 161 TYR D CE2   1 
ATOM   11273 C  CZ    . TYR D 2 161 ? 405.601 359.040 195.101 1.00 119.34 ? 161 TYR D CZ    1 
ATOM   11274 O  OH    . TYR D 2 161 ? 405.171 357.902 195.737 1.00 126.40 ? 161 TYR D OH    1 
ATOM   11275 N  N     . GLY D 2 162 ? 408.702 365.000 192.509 1.00 125.17 ? 162 GLY D N     1 
ATOM   11276 C  CA    . GLY D 2 162 ? 409.199 366.158 191.792 1.00 126.15 ? 162 GLY D CA    1 
ATOM   11277 C  C     . GLY D 2 162 ? 408.245 366.725 190.762 1.00 124.58 ? 162 GLY D C     1 
ATOM   11278 O  O     . GLY D 2 162 ? 407.360 367.520 191.093 1.00 127.38 ? 162 GLY D O     1 
ATOM   11279 N  N     . LYS D 2 163 ? 408.437 366.327 189.500 1.00 124.23 ? 163 LYS D N     1 
ATOM   11280 C  CA    . LYS D 2 163 ? 407.769 366.987 188.381 1.00 127.13 ? 163 LYS D CA    1 
ATOM   11281 C  C     . LYS D 2 163 ? 406.251 366.838 188.424 1.00 132.23 ? 163 LYS D C     1 
ATOM   11282 O  O     . LYS D 2 163 ? 405.538 367.667 187.847 1.00 135.43 ? 163 LYS D O     1 
ATOM   11283 C  CB    . LYS D 2 163 ? 408.306 366.433 187.062 1.00 122.42 ? 163 LYS D CB    1 
ATOM   11284 N  N     . LYS D 2 164 ? 405.735 365.803 189.082 1.00 110.56 ? 164 LYS D N     1 
ATOM   11285 C  CA    . LYS D 2 164 ? 404.297 365.582 189.087 1.00 106.29 ? 164 LYS D CA    1 
ATOM   11286 C  C     . LYS D 2 164 ? 403.581 366.667 189.890 1.00 109.29 ? 164 LYS D C     1 
ATOM   11287 O  O     . LYS D 2 164 ? 404.143 367.284 190.798 1.00 110.76 ? 164 LYS D O     1 
ATOM   11288 C  CB    . LYS D 2 164 ? 403.971 364.199 189.647 1.00 106.14 ? 164 LYS D CB    1 
ATOM   11289 C  CG    . LYS D 2 164 ? 404.497 363.068 188.781 1.00 110.16 ? 164 LYS D CG    1 
ATOM   11290 C  CD    . LYS D 2 164 ? 403.946 361.719 189.203 1.00 110.80 ? 164 LYS D CD    1 
ATOM   11291 C  CE    . LYS D 2 164 ? 404.340 360.633 188.215 1.00 113.66 ? 164 LYS D CE    1 
ATOM   11292 N  NZ    . LYS D 2 164 ? 403.627 360.774 186.914 1.00 109.80 ? 164 LYS D NZ    1 
ATOM   11293 N  N     . SER D 2 165 ? 402.319 366.894 189.533 1.00 118.46 ? 165 SER D N     1 
ATOM   11294 C  CA    . SER D 2 165 ? 401.540 367.975 190.121 1.00 118.56 ? 165 SER D CA    1 
ATOM   11295 C  C     . SER D 2 165 ? 401.288 367.729 191.604 1.00 117.97 ? 165 SER D C     1 
ATOM   11296 O  O     . SER D 2 165 ? 401.232 366.587 192.068 1.00 122.11 ? 165 SER D O     1 
ATOM   11297 C  CB    . SER D 2 165 ? 400.206 368.126 189.392 1.00 119.28 ? 165 SER D CB    1 
ATOM   11298 O  OG    . SER D 2 165 ? 400.399 368.229 187.992 1.00 120.38 ? 165 SER D OG    1 
ATOM   11299 N  N     . LYS D 2 166 ? 401.148 368.824 192.351 1.00 107.85 ? 166 LYS D N     1 
ATOM   11300 C  CA    . LYS D 2 166 ? 400.944 368.783 193.800 1.00 104.65 ? 166 LYS D CA    1 
ATOM   11301 C  C     . LYS D 2 166 ? 400.005 369.930 194.160 1.00 103.53 ? 166 LYS D C     1 
ATOM   11302 O  O     . LYS D 2 166 ? 400.440 371.082 194.249 1.00 111.85 ? 166 LYS D O     1 
ATOM   11303 C  CB    . LYS D 2 166 ? 402.265 368.903 194.548 1.00 104.90 ? 166 LYS D CB    1 
ATOM   11304 C  CG    . LYS D 2 166 ? 403.158 367.666 194.505 1.00 106.01 ? 166 LYS D CG    1 
ATOM   11305 C  CD    . LYS D 2 166 ? 404.597 368.000 194.901 1.00 111.76 ? 166 LYS D CD    1 
ATOM   11306 C  CE    . LYS D 2 166 ? 405.497 368.269 193.695 1.00 110.74 ? 166 LYS D CE    1 
ATOM   11307 N  NZ    . LYS D 2 166 ? 405.193 369.565 193.027 1.00 111.36 ? 166 LYS D NZ    1 
ATOM   11308 N  N     . LEU D 2 167 ? 398.730 369.608 194.375 1.00 102.73 ? 167 LEU D N     1 
ATOM   11309 C  CA    . LEU D 2 167 ? 397.686 370.587 194.659 1.00 101.33 ? 167 LEU D CA    1 
ATOM   11310 C  C     . LEU D 2 167 ? 397.257 370.471 196.114 1.00 106.35 ? 167 LEU D C     1 
ATOM   11311 O  O     . LEU D 2 167 ? 396.980 369.368 196.593 1.00 118.97 ? 167 LEU D O     1 
ATOM   11312 C  CB    . LEU D 2 167 ? 396.477 370.374 193.744 1.00 107.50 ? 167 LEU D CB    1 
ATOM   11313 C  CG    . LEU D 2 167 ? 396.736 370.312 192.238 1.00 107.62 ? 167 LEU D CG    1 
ATOM   11314 C  CD1   . LEU D 2 167 ? 395.450 369.985 191.503 1.00 110.97 ? 167 LEU D CD1   1 
ATOM   11315 C  CD2   . LEU D 2 167 ? 397.317 371.620 191.733 1.00 109.78 ? 167 LEU D CD2   1 
ATOM   11316 N  N     . GLU D 2 168 ? 397.212 371.608 196.810 1.00 108.38 ? 168 GLU D N     1 
ATOM   11317 C  CA    . GLU D 2 168 ? 396.688 371.695 198.166 1.00 108.01 ? 168 GLU D CA    1 
ATOM   11318 C  C     . GLU D 2 168 ? 395.305 372.327 198.133 1.00 109.25 ? 168 GLU D C     1 
ATOM   11319 O  O     . GLU D 2 168 ? 394.981 373.107 197.233 1.00 118.25 ? 168 GLU D O     1 
ATOM   11320 C  CB    . GLU D 2 168 ? 397.570 372.524 199.123 1.00 111.81 ? 168 GLU D CB    1 
ATOM   11321 C  CG    . GLU D 2 168 ? 398.970 372.006 199.514 1.00 119.46 ? 168 GLU D CG    1 
ATOM   11322 C  CD    . GLU D 2 168 ? 399.780 372.928 200.401 1.00 125.86 ? 168 GLU D CD    1 
ATOM   11323 O  OE1   . GLU D 2 168 ? 399.378 374.089 200.602 1.00 132.56 ? 168 GLU D OE1   1 
ATOM   11324 O  OE2   . GLU D 2 168 ? 400.822 372.475 200.915 1.00 122.92 ? 168 GLU D OE2   1 
ATOM   11325 N  N     . PHE D 2 169 ? 394.486 371.968 199.122 1.00 105.93 ? 169 PHE D N     1 
ATOM   11326 C  CA    . PHE D 2 169 ? 393.212 372.633 199.394 1.00 112.38 ? 169 PHE D CA    1 
ATOM   11327 C  C     . PHE D 2 169 ? 393.254 373.009 200.868 1.00 112.39 ? 169 PHE D C     1 
ATOM   11328 O  O     . PHE D 2 169 ? 392.798 372.247 201.724 1.00 112.99 ? 169 PHE D O     1 
ATOM   11329 C  CB    . PHE D 2 169 ? 392.021 371.751 199.072 1.00 110.98 ? 169 PHE D CB    1 
ATOM   11330 C  CG    . PHE D 2 169 ? 391.655 371.755 197.626 1.00 112.91 ? 169 PHE D CG    1 
ATOM   11331 C  CD1   . PHE D 2 169 ? 392.378 371.000 196.721 1.00 115.85 ? 169 PHE D CD1   1 
ATOM   11332 C  CD2   . PHE D 2 169 ? 390.626 372.550 197.160 1.00 115.63 ? 169 PHE D CD2   1 
ATOM   11333 C  CE1   . PHE D 2 169 ? 392.057 371.006 195.386 1.00 113.81 ? 169 PHE D CE1   1 
ATOM   11334 C  CE2   . PHE D 2 169 ? 390.308 372.570 195.821 1.00 118.59 ? 169 PHE D CE2   1 
ATOM   11335 C  CZ    . PHE D 2 169 ? 391.022 371.787 194.934 1.00 116.70 ? 169 PHE D CZ    1 
ATOM   11336 N  N     . SER D 2 170 ? 393.795 374.187 201.151 1.00 104.57 ? 170 SER D N     1 
ATOM   11337 C  CA    . SER D 2 170 ? 394.049 374.632 202.510 1.00 101.02 ? 170 SER D CA    1 
ATOM   11338 C  C     . SER D 2 170 ? 392.946 375.562 202.986 1.00 100.38 ? 170 SER D C     1 
ATOM   11339 O  O     . SER D 2 170 ? 392.293 376.244 202.193 1.00 111.11 ? 170 SER D O     1 
ATOM   11340 C  CB    . SER D 2 170 ? 395.391 375.350 202.601 1.00 102.60 ? 170 SER D CB    1 
ATOM   11341 O  OG    . SER D 2 170 ? 396.387 374.661 201.868 1.00 106.38 ? 170 SER D OG    1 
ATOM   11342 N  N     . ILE D 2 171 ? 392.750 375.576 204.299 1.00 89.32  ? 171 ILE D N     1 
ATOM   11343 C  CA    . ILE D 2 171 ? 391.796 376.455 204.958 1.00 89.83  ? 171 ILE D CA    1 
ATOM   11344 C  C     . ILE D 2 171 ? 392.576 377.679 205.408 1.00 99.46  ? 171 ILE D C     1 
ATOM   11345 O  O     . ILE D 2 171 ? 393.325 377.627 206.389 1.00 106.37 ? 171 ILE D O     1 
ATOM   11346 C  CB    . ILE D 2 171 ? 391.100 375.752 206.131 1.00 92.76  ? 171 ILE D CB    1 
ATOM   11347 C  CG1   . ILE D 2 171 ? 390.716 374.333 205.694 1.00 93.71  ? 171 ILE D CG1   1 
ATOM   11348 C  CG2   . ILE D 2 171 ? 389.880 376.565 206.608 1.00 101.49 ? 171 ILE D CG2   1 
ATOM   11349 C  CD1   . ILE D 2 171 ? 389.643 373.675 206.485 1.00 97.55  ? 171 ILE D CD1   1 
ATOM   11350 N  N     . TYR D 2 172 ? 392.416 378.771 204.673 1.00 121.04 ? 172 TYR D N     1 
ATOM   11351 C  CA    . TYR D 2 172 ? 393.107 380.001 205.014 1.00 115.57 ? 172 TYR D CA    1 
ATOM   11352 C  C     . TYR D 2 172 ? 392.584 380.509 206.359 1.00 115.74 ? 172 TYR D C     1 
ATOM   11353 O  O     . TYR D 2 172 ? 391.389 380.357 206.642 1.00 117.72 ? 172 TYR D O     1 
ATOM   11354 C  CB    . TYR D 2 172 ? 392.876 381.043 203.920 1.00 115.03 ? 172 TYR D CB    1 
ATOM   11355 C  CG    . TYR D 2 172 ? 393.791 382.235 203.997 1.00 117.28 ? 172 TYR D CG    1 
ATOM   11356 C  CD1   . TYR D 2 172 ? 395.052 382.204 203.421 1.00 118.69 ? 172 TYR D CD1   1 
ATOM   11357 C  CD2   . TYR D 2 172 ? 393.395 383.392 204.645 1.00 118.77 ? 172 TYR D CD2   1 
ATOM   11358 C  CE1   . TYR D 2 172 ? 395.893 383.294 203.490 1.00 118.05 ? 172 TYR D CE1   1 
ATOM   11359 C  CE2   . TYR D 2 172 ? 394.227 384.483 204.723 1.00 123.54 ? 172 TYR D CE2   1 
ATOM   11360 C  CZ    . TYR D 2 172 ? 395.474 384.432 204.143 1.00 122.45 ? 172 TYR D CZ    1 
ATOM   11361 O  OH    . TYR D 2 172 ? 396.303 385.526 204.218 1.00 120.31 ? 172 TYR D OH    1 
ATOM   11362 N  N     . PRO D 2 173 ? 393.432 381.078 207.228 1.00 94.92  ? 173 PRO D N     1 
ATOM   11363 C  CA    . PRO D 2 173 ? 392.907 381.609 208.493 1.00 98.58  ? 173 PRO D CA    1 
ATOM   11364 C  C     . PRO D 2 173 ? 391.934 382.756 208.259 1.00 102.85 ? 173 PRO D C     1 
ATOM   11365 O  O     . PRO D 2 173 ? 392.167 383.636 207.430 1.00 103.06 ? 173 PRO D O     1 
ATOM   11366 C  CB    . PRO D 2 173 ? 394.164 382.075 209.236 1.00 98.79  ? 173 PRO D CB    1 
ATOM   11367 C  CG    . PRO D 2 173 ? 395.182 382.255 208.185 1.00 99.15  ? 173 PRO D CG    1 
ATOM   11368 C  CD    . PRO D 2 173 ? 394.905 381.169 207.210 1.00 93.42  ? 173 PRO D CD    1 
ATOM   11369 N  N     . ALA D 2 174 ? 390.835 382.733 209.006 1.00 110.40 ? 174 ALA D N     1 
ATOM   11370 C  CA    . ALA D 2 174 ? 389.771 383.695 208.788 1.00 110.11 ? 174 ALA D CA    1 
ATOM   11371 C  C     . ALA D 2 174 ? 390.233 385.096 209.197 1.00 113.65 ? 174 ALA D C     1 
ATOM   11372 O  O     . ALA D 2 174 ? 391.110 385.239 210.052 1.00 113.11 ? 174 ALA D O     1 
ATOM   11373 C  CB    . ALA D 2 174 ? 388.528 383.292 209.575 1.00 110.60 ? 174 ALA D CB    1 
ATOM   11374 N  N     . PRO D 2 175 ? 389.669 386.150 208.593 1.00 110.99 ? 175 PRO D N     1 
ATOM   11375 C  CA    . PRO D 2 175 ? 390.205 387.490 208.875 1.00 110.62 ? 175 PRO D CA    1 
ATOM   11376 C  C     . PRO D 2 175 ? 389.910 387.973 210.278 1.00 113.82 ? 175 PRO D C     1 
ATOM   11377 O  O     . PRO D 2 175 ? 390.816 388.462 210.964 1.00 119.07 ? 175 PRO D O     1 
ATOM   11378 C  CB    . PRO D 2 175 ? 389.514 388.366 207.824 1.00 109.73 ? 175 PRO D CB    1 
ATOM   11379 C  CG    . PRO D 2 175 ? 388.238 387.700 207.576 1.00 110.84 ? 175 PRO D CG    1 
ATOM   11380 C  CD    . PRO D 2 175 ? 388.499 386.224 207.697 1.00 112.35 ? 175 PRO D CD    1 
ATOM   11381 N  N     . GLN D 2 176 ? 388.665 387.835 210.727 1.00 115.81 ? 176 GLN D N     1 
ATOM   11382 C  CA    . GLN D 2 176 ? 388.225 388.380 212.005 1.00 115.36 ? 176 GLN D CA    1 
ATOM   11383 C  C     . GLN D 2 176 ? 388.322 387.335 213.109 1.00 116.50 ? 176 GLN D C     1 
ATOM   11384 O  O     . GLN D 2 176 ? 388.974 387.563 214.134 1.00 114.94 ? 176 GLN D O     1 
ATOM   11385 C  CB    . GLN D 2 176 ? 386.788 388.895 211.874 1.00 117.28 ? 176 GLN D CB    1 
ATOM   11386 C  CG    . GLN D 2 176 ? 386.649 390.138 211.005 1.00 118.65 ? 176 GLN D CG    1 
ATOM   11387 C  CD    . GLN D 2 176 ? 387.187 391.390 211.673 1.00 120.93 ? 176 GLN D CD    1 
ATOM   11388 O  OE1   . GLN D 2 176 ? 387.384 391.428 212.887 1.00 119.79 ? 176 GLN D OE1   1 
ATOM   11389 N  NE2   . GLN D 2 176 ? 387.435 392.422 210.876 1.00 125.77 ? 176 GLN D NE2   1 
ATOM   11390 N  N     . VAL D 2 177 ? 387.688 386.185 212.903 1.00 110.70 ? 177 VAL D N     1 
ATOM   11391 C  CA    . VAL D 2 177 ? 387.632 385.134 213.906 1.00 113.54 ? 177 VAL D CA    1 
ATOM   11392 C  C     . VAL D 2 177 ? 388.815 384.190 213.720 1.00 121.23 ? 177 VAL D C     1 
ATOM   11393 O  O     . VAL D 2 177 ? 389.452 384.146 212.666 1.00 127.36 ? 177 VAL D O     1 
ATOM   11394 C  CB    . VAL D 2 177 ? 386.289 384.373 213.832 1.00 113.50 ? 177 VAL D CB    1 
ATOM   11395 C  CG1   . VAL D 2 177 ? 386.242 383.454 212.602 1.00 105.49 ? 177 VAL D CG1   1 
ATOM   11396 C  CG2   . VAL D 2 177 ? 386.012 383.605 215.134 1.00 118.47 ? 177 VAL D CG2   1 
ATOM   11397 N  N     . SER D 2 178 ? 389.120 383.435 214.772 1.00 124.11 ? 178 SER D N     1 
ATOM   11398 C  CA    . SER D 2 178 ? 390.119 382.380 214.707 1.00 121.99 ? 178 SER D CA    1 
ATOM   11399 C  C     . SER D 2 178 ? 389.911 381.451 215.893 1.00 121.42 ? 178 SER D C     1 
ATOM   11400 O  O     . SER D 2 178 ? 389.605 381.909 216.996 1.00 123.21 ? 178 SER D O     1 
ATOM   11401 C  CB    . SER D 2 178 ? 391.544 382.945 214.713 1.00 128.37 ? 178 SER D CB    1 
ATOM   11402 O  OG    . SER D 2 178 ? 391.790 383.729 213.558 1.00 129.00 ? 178 SER D OG    1 
ATOM   11403 N  N     . THR D 2 179 ? 390.085 380.151 215.654 1.00 125.78 ? 179 THR D N     1 
ATOM   11404 C  CA    . THR D 2 179 ? 389.910 379.121 216.669 1.00 125.75 ? 179 THR D CA    1 
ATOM   11405 C  C     . THR D 2 179 ? 391.231 378.708 217.318 1.00 123.93 ? 179 THR D C     1 
ATOM   11406 O  O     . THR D 2 179 ? 391.314 377.623 217.902 1.00 120.34 ? 179 THR D O     1 
ATOM   11407 C  CB    . THR D 2 179 ? 389.224 377.900 216.056 1.00 126.15 ? 179 THR D CB    1 
ATOM   11408 O  OG1   . THR D 2 179 ? 390.010 377.409 214.965 1.00 126.08 ? 179 THR D OG1   1 
ATOM   11409 C  CG2   . THR D 2 179 ? 387.836 378.260 215.550 1.00 125.63 ? 179 THR D CG2   1 
ATOM   11410 N  N     . ALA D 2 180 ? 392.263 379.545 217.226 1.00 106.91 ? 180 ALA D N     1 
ATOM   11411 C  CA    . ALA D 2 180 ? 393.565 379.219 217.792 1.00 106.31 ? 180 ALA D CA    1 
ATOM   11412 C  C     . ALA D 2 180 ? 394.379 380.499 217.870 1.00 103.42 ? 180 ALA D C     1 
ATOM   11413 O  O     . ALA D 2 180 ? 394.387 381.283 216.918 1.00 109.03 ? 180 ALA D O     1 
ATOM   11414 C  CB    . ALA D 2 180 ? 394.292 378.170 216.944 1.00 102.44 ? 180 ALA D CB    1 
ATOM   11415 N  N     . VAL D 2 181 ? 395.043 380.718 219.005 1.00 98.99  ? 181 VAL D N     1 
ATOM   11416 C  CA    . VAL D 2 181 ? 395.814 381.946 219.174 1.00 101.06 ? 181 VAL D CA    1 
ATOM   11417 C  C     . VAL D 2 181 ? 397.114 381.884 218.375 1.00 103.80 ? 181 VAL D C     1 
ATOM   11418 O  O     . VAL D 2 181 ? 397.538 382.885 217.792 1.00 106.89 ? 181 VAL D O     1 
ATOM   11419 C  CB    . VAL D 2 181 ? 396.062 382.230 220.668 1.00 97.41  ? 181 VAL D CB    1 
ATOM   11420 C  CG1   . VAL D 2 181 ? 394.742 382.262 221.424 1.00 106.29 ? 181 VAL D CG1   1 
ATOM   11421 C  CG2   . VAL D 2 181 ? 397.011 381.220 221.290 1.00 101.87 ? 181 VAL D CG2   1 
ATOM   11422 N  N     . VAL D 2 182 ? 397.742 380.707 218.296 1.00 100.85 ? 182 VAL D N     1 
ATOM   11423 C  CA    . VAL D 2 182 ? 399.024 380.531 217.604 1.00 95.63  ? 182 VAL D CA    1 
ATOM   11424 C  C     . VAL D 2 182 ? 398.855 380.289 216.098 1.00 97.52  ? 182 VAL D C     1 
ATOM   11425 O  O     . VAL D 2 182 ? 399.807 379.869 215.412 1.00 104.88 ? 182 VAL D O     1 
ATOM   11426 C  CB    . VAL D 2 182 ? 399.845 379.395 218.254 1.00 98.96  ? 182 VAL D CB    1 
ATOM   11427 C  CG1   . VAL D 2 182 ? 400.167 379.741 219.701 1.00 99.98  ? 182 VAL D CG1   1 
ATOM   11428 C  CG2   . VAL D 2 182 ? 399.142 378.027 218.179 1.00 106.56 ? 182 VAL D CG2   1 
ATOM   11429 N  N     . GLU D 2 183 ? 397.644 380.532 215.584 1.00 100.63 ? 183 GLU D N     1 
ATOM   11430 C  CA    . GLU D 2 183 ? 397.380 380.448 214.149 1.00 102.32 ? 183 GLU D CA    1 
ATOM   11431 C  C     . GLU D 2 183 ? 398.339 381.264 213.290 1.00 105.64 ? 183 GLU D C     1 
ATOM   11432 O  O     . GLU D 2 183 ? 398.758 380.745 212.244 1.00 111.21 ? 183 GLU D O     1 
ATOM   11433 C  CB    . GLU D 2 183 ? 395.938 380.894 213.843 1.00 107.50 ? 183 GLU D CB    1 
ATOM   11434 C  CG    . GLU D 2 183 ? 395.189 379.978 212.906 1.00 108.91 ? 183 GLU D CG    1 
ATOM   11435 C  CD    . GLU D 2 183 ? 393.732 380.370 212.761 1.00 111.90 ? 183 GLU D CD    1 
ATOM   11436 O  OE1   . GLU D 2 183 ? 393.455 381.569 212.552 1.00 112.35 ? 183 GLU D OE1   1 
ATOM   11437 O  OE2   . GLU D 2 183 ? 392.863 379.479 212.863 1.00 109.46 ? 183 GLU D OE2   1 
ATOM   11438 N  N     . PRO D 2 184 ? 398.689 382.521 213.617 1.00 96.57  ? 184 PRO D N     1 
ATOM   11439 C  CA    . PRO D 2 184 ? 399.649 383.243 212.759 1.00 100.35 ? 184 PRO D CA    1 
ATOM   11440 C  C     . PRO D 2 184 ? 401.008 382.575 212.649 1.00 99.98  ? 184 PRO D C     1 
ATOM   11441 O  O     . PRO D 2 184 ? 401.557 382.493 211.543 1.00 99.65  ? 184 PRO D O     1 
ATOM   11442 C  CB    . PRO D 2 184 ? 399.752 384.616 213.435 1.00 97.94  ? 184 PRO D CB    1 
ATOM   11443 C  CG    . PRO D 2 184 ? 398.480 384.776 214.150 1.00 97.17  ? 184 PRO D CG    1 
ATOM   11444 C  CD    . PRO D 2 184 ? 398.128 383.415 214.646 1.00 93.51  ? 184 PRO D CD    1 
ATOM   11445 N  N     . TYR D 2 185 ? 401.553 382.071 213.760 1.00 98.96  ? 185 TYR D N     1 
ATOM   11446 C  CA    . TYR D 2 185 ? 402.842 381.387 213.712 1.00 96.78  ? 185 TYR D CA    1 
ATOM   11447 C  C     . TYR D 2 185 ? 402.760 380.136 212.849 1.00 102.54 ? 185 TYR D C     1 
ATOM   11448 O  O     . TYR D 2 185 ? 403.599 379.926 211.956 1.00 104.03 ? 185 TYR D O     1 
ATOM   11449 C  CB    . TYR D 2 185 ? 403.301 381.018 215.128 1.00 97.60  ? 185 TYR D CB    1 
ATOM   11450 C  CG    . TYR D 2 185 ? 403.751 382.155 216.042 1.00 93.88  ? 185 TYR D CG    1 
ATOM   11451 C  CD1   . TYR D 2 185 ? 403.697 383.488 215.653 1.00 93.02  ? 185 TYR D CD1   1 
ATOM   11452 C  CD2   . TYR D 2 185 ? 404.239 381.874 217.311 1.00 97.87  ? 185 TYR D CD2   1 
ATOM   11453 C  CE1   . TYR D 2 185 ? 404.115 384.494 216.495 1.00 97.48  ? 185 TYR D CE1   1 
ATOM   11454 C  CE2   . TYR D 2 185 ? 404.655 382.877 218.158 1.00 93.11  ? 185 TYR D CE2   1 
ATOM   11455 C  CZ    . TYR D 2 185 ? 404.591 384.183 217.746 1.00 97.78  ? 185 TYR D CZ    1 
ATOM   11456 O  OH    . TYR D 2 185 ? 405.006 385.186 218.590 1.00 107.30 ? 185 TYR D OH    1 
ATOM   11457 N  N     . ASN D 2 186 ? 401.738 379.301 213.091 1.00 110.97 ? 186 ASN D N     1 
ATOM   11458 C  CA    . ASN D 2 186 ? 401.603 378.065 212.321 1.00 110.68 ? 186 ASN D CA    1 
ATOM   11459 C  C     . ASN D 2 186 ? 401.412 378.355 210.837 1.00 116.55 ? 186 ASN D C     1 
ATOM   11460 O  O     . ASN D 2 186 ? 402.063 377.733 209.984 1.00 125.53 ? 186 ASN D O     1 
ATOM   11461 C  CB    . ASN D 2 186 ? 400.432 377.241 212.849 1.00 106.72 ? 186 ASN D CB    1 
ATOM   11462 C  CG    . ASN D 2 186 ? 400.626 376.810 214.281 1.00 109.39 ? 186 ASN D CG    1 
ATOM   11463 O  OD1   . ASN D 2 186 ? 401.747 376.774 214.783 1.00 112.89 ? 186 ASN D OD1   1 
ATOM   11464 N  ND2   . ASN D 2 186 ? 399.531 376.472 214.947 1.00 116.07 ? 186 ASN D ND2   1 
ATOM   11465 N  N     . SER D 2 187 ? 400.549 379.321 210.519 1.00 101.62 ? 187 SER D N     1 
ATOM   11466 C  CA    . SER D 2 187 ? 400.262 379.663 209.133 1.00 99.33  ? 187 SER D CA    1 
ATOM   11467 C  C     . SER D 2 187 ? 401.497 380.195 208.422 1.00 104.92 ? 187 SER D C     1 
ATOM   11468 O  O     . SER D 2 187 ? 401.796 379.784 207.296 1.00 108.08 ? 187 SER D O     1 
ATOM   11469 C  CB    . SER D 2 187 ? 399.138 380.691 209.085 1.00 103.01 ? 187 SER D CB    1 
ATOM   11470 O  OG    . SER D 2 187 ? 399.663 381.985 209.305 1.00 119.23 ? 187 SER D OG    1 
ATOM   11471 N  N     . ILE D 2 188 ? 402.221 381.119 209.064 1.00 106.48 ? 188 ILE D N     1 
ATOM   11472 C  CA    . ILE D 2 188 ? 403.386 381.726 208.428 1.00 104.14 ? 188 ILE D CA    1 
ATOM   11473 C  C     . ILE D 2 188 ? 404.443 380.669 208.158 1.00 100.75 ? 188 ILE D C     1 
ATOM   11474 O  O     . ILE D 2 188 ? 405.030 380.623 207.069 1.00 101.39 ? 188 ILE D O     1 
ATOM   11475 C  CB    . ILE D 2 188 ? 403.932 382.874 209.303 1.00 107.16 ? 188 ILE D CB    1 
ATOM   11476 C  CG1   . ILE D 2 188 ? 402.990 384.087 209.266 1.00 110.08 ? 188 ILE D CG1   1 
ATOM   11477 C  CG2   . ILE D 2 188 ? 405.344 383.294 208.875 1.00 101.83 ? 188 ILE D CG2   1 
ATOM   11478 C  CD1   . ILE D 2 188 ? 403.046 384.931 207.990 1.00 104.93 ? 188 ILE D CD1   1 
ATOM   11479 N  N     . LEU D 2 189 ? 404.678 379.780 209.126 1.00 95.10  ? 189 LEU D N     1 
ATOM   11480 C  CA    . LEU D 2 189 ? 405.705 378.765 208.925 1.00 92.82  ? 189 LEU D CA    1 
ATOM   11481 C  C     . LEU D 2 189 ? 405.313 377.779 207.825 1.00 98.35  ? 189 LEU D C     1 
ATOM   11482 O  O     . LEU D 2 189 ? 406.148 377.428 206.971 1.00 107.36 ? 189 LEU D O     1 
ATOM   11483 C  CB    . LEU D 2 189 ? 405.982 378.046 210.242 1.00 92.09  ? 189 LEU D CB    1 
ATOM   11484 C  CG    . LEU D 2 189 ? 406.589 378.933 211.340 1.00 93.48  ? 189 LEU D CG    1 
ATOM   11485 C  CD1   . LEU D 2 189 ? 406.411 378.334 212.729 1.00 98.76  ? 189 LEU D CD1   1 
ATOM   11486 C  CD2   . LEU D 2 189 ? 408.060 379.215 211.063 1.00 101.20 ? 189 LEU D CD2   1 
ATOM   11487 N  N     . THR D 2 190 ? 404.044 377.342 207.797 1.00 107.97 ? 190 THR D N     1 
ATOM   11488 C  CA    . THR D 2 190 ? 403.677 376.376 206.767 1.00 113.41 ? 190 THR D CA    1 
ATOM   11489 C  C     . THR D 2 190 ? 403.687 376.996 205.379 1.00 117.49 ? 190 THR D C     1 
ATOM   11490 O  O     . THR D 2 190 ? 404.137 376.340 204.441 1.00 126.71 ? 190 THR D O     1 
ATOM   11491 C  CB    . THR D 2 190 ? 402.322 375.708 207.041 1.00 115.77 ? 190 THR D CB    1 
ATOM   11492 O  OG1   . THR D 2 190 ? 402.095 374.681 206.067 1.00 122.60 ? 190 THR D OG1   1 
ATOM   11493 C  CG2   . THR D 2 190 ? 401.158 376.672 207.008 1.00 116.60 ? 190 THR D CG2   1 
ATOM   11494 N  N     . THR D 2 191 ? 403.228 378.245 205.209 1.00 110.25 ? 191 THR D N     1 
ATOM   11495 C  CA    . THR D 2 191 ? 403.272 378.808 203.857 1.00 111.29 ? 191 THR D CA    1 
ATOM   11496 C  C     . THR D 2 191 ? 404.701 379.162 203.448 1.00 110.83 ? 191 THR D C     1 
ATOM   11497 O  O     . THR D 2 191 ? 405.026 379.099 202.252 1.00 110.74 ? 191 THR D O     1 
ATOM   11498 C  CB    . THR D 2 191 ? 402.325 380.009 203.692 1.00 110.31 ? 191 THR D CB    1 
ATOM   11499 O  OG1   . THR D 2 191 ? 402.501 380.565 202.382 1.00 112.68 ? 191 THR D OG1   1 
ATOM   11500 C  CG2   . THR D 2 191 ? 402.547 381.102 204.701 1.00 112.05 ? 191 THR D CG2   1 
ATOM   11501 N  N     . HIS D 2 192 ? 405.577 379.475 204.416 1.00 103.10 ? 192 HIS D N     1 
ATOM   11502 C  CA    . HIS D 2 192 ? 407.003 379.599 204.115 1.00 95.18  ? 192 HIS D CA    1 
ATOM   11503 C  C     . HIS D 2 192 ? 407.557 378.312 203.525 1.00 95.41  ? 192 HIS D C     1 
ATOM   11504 O  O     . HIS D 2 192 ? 408.280 378.345 202.524 1.00 102.92 ? 192 HIS D O     1 
ATOM   11505 C  CB    . HIS D 2 192 ? 407.780 379.965 205.381 1.00 96.01  ? 192 HIS D CB    1 
ATOM   11506 C  CG    . HIS D 2 192 ? 409.268 379.990 205.199 1.00 97.11  ? 192 HIS D CG    1 
ATOM   11507 N  ND1   . HIS D 2 192 ? 410.140 379.568 206.179 1.00 98.73  ? 192 HIS D ND1   1 
ATOM   11508 C  CD2   . HIS D 2 192 ? 410.040 380.405 204.166 1.00 100.47 ? 192 HIS D CD2   1 
ATOM   11509 C  CE1   . HIS D 2 192 ? 411.383 379.705 205.751 1.00 96.20  ? 192 HIS D CE1   1 
ATOM   11510 N  NE2   . HIS D 2 192 ? 411.349 380.211 204.532 1.00 96.72  ? 192 HIS D NE2   1 
ATOM   11511 N  N     . THR D 2 193 ? 407.232 377.169 204.128 1.00 103.89 ? 193 THR D N     1 
ATOM   11512 C  CA    . THR D 2 193 ? 407.704 375.908 203.555 1.00 104.22 ? 193 THR D CA    1 
ATOM   11513 C  C     . THR D 2 193 ? 406.967 375.544 202.268 1.00 106.77 ? 193 THR D C     1 
ATOM   11514 O  O     . THR D 2 193 ? 407.546 374.899 201.387 1.00 104.01 ? 193 THR D O     1 
ATOM   11515 C  CB    . THR D 2 193 ? 407.560 374.781 204.570 1.00 108.25 ? 193 THR D CB    1 
ATOM   11516 O  OG1   . THR D 2 193 ? 406.222 374.776 205.082 1.00 116.40 ? 193 THR D OG1   1 
ATOM   11517 C  CG2   . THR D 2 193 ? 408.559 374.939 205.707 1.00 102.70 ? 193 THR D CG2   1 
ATOM   11518 N  N     . THR D 2 194 ? 405.703 375.943 202.140 1.00 120.11 ? 194 THR D N     1 
ATOM   11519 C  CA    . THR D 2 194 ? 404.878 375.532 201.010 1.00 118.69 ? 194 THR D CA    1 
ATOM   11520 C  C     . THR D 2 194 ? 405.232 376.285 199.732 1.00 123.22 ? 194 THR D C     1 
ATOM   11521 O  O     . THR D 2 194 ? 404.989 375.763 198.636 1.00 127.02 ? 194 THR D O     1 
ATOM   11522 C  CB    . THR D 2 194 ? 403.398 375.743 201.356 1.00 119.91 ? 194 THR D CB    1 
ATOM   11523 O  OG1   . THR D 2 194 ? 403.075 375.014 202.547 1.00 118.70 ? 194 THR D OG1   1 
ATOM   11524 C  CG2   . THR D 2 194 ? 402.480 375.250 200.258 1.00 117.77 ? 194 THR D CG2   1 
ATOM   11525 N  N     . LEU D 2 195 ? 405.790 377.500 199.854 1.00 121.62 ? 195 LEU D N     1 
ATOM   11526 C  CA    . LEU D 2 195 ? 406.046 378.333 198.677 1.00 116.24 ? 195 LEU D CA    1 
ATOM   11527 C  C     . LEU D 2 195 ? 406.983 377.666 197.675 1.00 117.45 ? 195 LEU D C     1 
ATOM   11528 O  O     . LEU D 2 195 ? 406.796 377.816 196.462 1.00 116.93 ? 195 LEU D O     1 
ATOM   11529 C  CB    . LEU D 2 195 ? 406.642 379.678 199.093 1.00 112.73 ? 195 LEU D CB    1 
ATOM   11530 C  CG    . LEU D 2 195 ? 405.652 380.829 199.246 1.00 111.78 ? 195 LEU D CG    1 
ATOM   11531 C  CD1   . LEU D 2 195 ? 406.180 381.847 200.240 1.00 115.27 ? 195 LEU D CD1   1 
ATOM   11532 C  CD2   . LEU D 2 195 ? 405.379 381.479 197.898 1.00 117.67 ? 195 LEU D CD2   1 
ATOM   11533 N  N     . GLU D 2 196 ? 407.982 376.926 198.151 1.00 119.16 ? 196 GLU D N     1 
ATOM   11534 C  CA    . GLU D 2 196 ? 408.968 376.327 197.259 1.00 116.59 ? 196 GLU D CA    1 
ATOM   11535 C  C     . GLU D 2 196 ? 408.463 375.046 196.610 1.00 117.99 ? 196 GLU D C     1 
ATOM   11536 O  O     . GLU D 2 196 ? 408.739 374.801 195.430 1.00 119.41 ? 196 GLU D O     1 
ATOM   11537 C  CB    . GLU D 2 196 ? 410.269 376.024 198.010 1.00 120.34 ? 196 GLU D CB    1 
ATOM   11538 C  CG    . GLU D 2 196 ? 410.984 377.237 198.623 1.00 122.78 ? 196 GLU D CG    1 
ATOM   11539 C  CD    . GLU D 2 196 ? 410.394 377.711 199.945 1.00 124.76 ? 196 GLU D CD    1 
ATOM   11540 O  OE1   . GLU D 2 196 ? 409.526 377.011 200.509 1.00 129.36 ? 196 GLU D OE1   1 
ATOM   11541 O  OE2   . GLU D 2 196 ? 410.802 378.791 200.420 1.00 123.60 ? 196 GLU D OE2   1 
ATOM   11542 N  N     . HIS D 2 197 ? 407.720 374.229 197.358 1.00 118.65 ? 197 HIS D N     1 
ATOM   11543 C  CA    . HIS D 2 197 ? 407.383 372.877 196.936 1.00 121.31 ? 197 HIS D CA    1 
ATOM   11544 C  C     . HIS D 2 197 ? 406.013 372.760 196.287 1.00 120.15 ? 197 HIS D C     1 
ATOM   11545 O  O     . HIS D 2 197 ? 405.795 371.819 195.517 1.00 121.00 ? 197 HIS D O     1 
ATOM   11546 C  CB    . HIS D 2 197 ? 407.447 371.930 198.137 1.00 118.98 ? 197 HIS D CB    1 
ATOM   11547 C  CG    . HIS D 2 197 ? 408.783 371.909 198.810 1.00 123.70 ? 197 HIS D CG    1 
ATOM   11548 N  ND1   . HIS D 2 197 ? 409.927 371.469 198.179 1.00 122.82 ? 197 HIS D ND1   1 
ATOM   11549 C  CD2   . HIS D 2 197 ? 409.161 372.282 200.055 1.00 121.83 ? 197 HIS D CD2   1 
ATOM   11550 C  CE1   . HIS D 2 197 ? 410.950 371.568 199.008 1.00 121.30 ? 197 HIS D CE1   1 
ATOM   11551 N  NE2   . HIS D 2 197 ? 410.512 372.059 200.153 1.00 123.94 ? 197 HIS D NE2   1 
ATOM   11552 N  N     . SER D 2 198 ? 405.090 373.675 196.566 1.00 120.12 ? 198 SER D N     1 
ATOM   11553 C  CA    . SER D 2 198 ? 403.757 373.555 196.003 1.00 115.99 ? 198 SER D CA    1 
ATOM   11554 C  C     . SER D 2 198 ? 403.752 373.890 194.517 1.00 120.00 ? 198 SER D C     1 
ATOM   11555 O  O     . SER D 2 198 ? 404.719 374.419 193.963 1.00 124.68 ? 198 SER D O     1 
ATOM   11556 C  CB    . SER D 2 198 ? 402.784 374.477 196.725 1.00 120.39 ? 198 SER D CB    1 
ATOM   11557 O  OG    . SER D 2 198 ? 401.455 374.227 196.310 1.00 124.79 ? 198 SER D OG    1 
ATOM   11558 N  N     . ASP D 2 199 ? 402.634 373.553 193.876 1.00 116.50 ? 199 ASP D N     1 
ATOM   11559 C  CA    . ASP D 2 199 ? 402.316 373.954 192.512 1.00 116.28 ? 199 ASP D CA    1 
ATOM   11560 C  C     . ASP D 2 199 ? 401.121 374.889 192.436 1.00 115.71 ? 199 ASP D C     1 
ATOM   11561 O  O     . ASP D 2 199 ? 401.175 375.891 191.723 1.00 118.10 ? 199 ASP D O     1 
ATOM   11562 C  CB    . ASP D 2 199 ? 402.042 372.716 191.653 1.00 120.76 ? 199 ASP D CB    1 
ATOM   11563 C  CG    . ASP D 2 199 ? 403.274 371.858 191.460 1.00 124.56 ? 199 ASP D CG    1 
ATOM   11564 O  OD1   . ASP D 2 199 ? 404.322 372.403 191.055 1.00 122.01 ? 199 ASP D OD1   1 
ATOM   11565 O  OD2   . ASP D 2 199 ? 403.196 370.637 191.711 1.00 129.79 ? 199 ASP D OD2   1 
ATOM   11566 N  N     . CYS D 2 200 ? 400.040 374.586 193.151 1.00 111.75 ? 200 CYS D N     1 
ATOM   11567 C  CA    . CYS D 2 200 ? 398.881 375.474 193.207 1.00 107.22 ? 200 CYS D CA    1 
ATOM   11568 C  C     . CYS D 2 200 ? 398.040 375.089 194.411 1.00 102.89 ? 200 CYS D C     1 
ATOM   11569 O  O     . CYS D 2 200 ? 397.525 373.969 194.465 1.00 113.62 ? 200 CYS D O     1 
ATOM   11570 C  CB    . CYS D 2 200 ? 398.060 375.385 191.922 1.00 111.50 ? 200 CYS D CB    1 
ATOM   11571 S  SG    . CYS D 2 200 ? 396.767 376.633 191.784 1.00 118.34 ? 200 CYS D SG    1 
ATOM   11572 N  N     . ALA D 2 201 ? 397.891 376.014 195.358 1.00 81.64  ? 201 ALA D N     1 
ATOM   11573 C  CA    . ALA D 2 201 ? 397.129 375.804 196.584 1.00 91.68  ? 201 ALA D CA    1 
ATOM   11574 C  C     . ALA D 2 201 ? 395.883 376.674 196.554 1.00 101.17 ? 201 ALA D C     1 
ATOM   11575 O  O     . ALA D 2 201 ? 395.974 377.881 196.313 1.00 107.29 ? 201 ALA D O     1 
ATOM   11576 C  CB    . ALA D 2 201 ? 397.974 376.133 197.814 1.00 97.85  ? 201 ALA D CB    1 
ATOM   11577 N  N     . PHE D 2 202 ? 394.728 376.061 196.803 1.00 105.71 ? 202 PHE D N     1 
ATOM   11578 C  CA    . PHE D 2 202 ? 393.435 376.729 196.722 1.00 99.61  ? 202 PHE D CA    1 
ATOM   11579 C  C     . PHE D 2 202 ? 392.968 377.098 198.127 1.00 106.68 ? 202 PHE D C     1 
ATOM   11580 O  O     . PHE D 2 202 ? 392.667 376.216 198.937 1.00 110.08 ? 202 PHE D O     1 
ATOM   11581 C  CB    . PHE D 2 202 ? 392.420 375.819 196.031 1.00 95.07  ? 202 PHE D CB    1 
ATOM   11582 C  CG    . PHE D 2 202 ? 392.867 375.338 194.681 1.00 102.29 ? 202 PHE D CG    1 
ATOM   11583 C  CD1   . PHE D 2 202 ? 392.703 376.130 193.559 1.00 105.43 ? 202 PHE D CD1   1 
ATOM   11584 C  CD2   . PHE D 2 202 ? 393.479 374.106 194.541 1.00 104.89 ? 202 PHE D CD2   1 
ATOM   11585 C  CE1   . PHE D 2 202 ? 393.122 375.690 192.320 1.00 107.25 ? 202 PHE D CE1   1 
ATOM   11586 C  CE2   . PHE D 2 202 ? 393.899 373.662 193.305 1.00 99.22  ? 202 PHE D CE2   1 
ATOM   11587 C  CZ    . PHE D 2 202 ? 393.722 374.455 192.193 1.00 100.79 ? 202 PHE D CZ    1 
ATOM   11588 N  N     . MET D 2 203 ? 392.892 378.397 198.402 1.00 111.36 ? 203 MET D N     1 
ATOM   11589 C  CA    . MET D 2 203 ? 392.474 378.885 199.708 1.00 104.48 ? 203 MET D CA    1 
ATOM   11590 C  C     . MET D 2 203 ? 390.980 378.701 199.936 1.00 105.68 ? 203 MET D C     1 
ATOM   11591 O  O     . MET D 2 203 ? 390.177 378.703 199.000 1.00 109.79 ? 203 MET D O     1 
ATOM   11592 C  CB    . MET D 2 203 ? 392.823 380.367 199.867 1.00 108.38 ? 203 MET D CB    1 
ATOM   11593 C  CG    . MET D 2 203 ? 394.284 380.794 199.673 1.00 111.79 ? 203 MET D CG    1 
ATOM   11594 S  SD    . MET D 2 203 ? 395.554 379.844 200.554 1.00 130.41 ? 203 MET D SD    1 
ATOM   11595 C  CE    . MET D 2 203 ? 395.769 378.344 199.612 1.00 116.55 ? 203 MET D CE    1 
ATOM   11596 N  N     . VAL D 2 204 ? 390.619 378.554 201.209 1.00 103.60 ? 204 VAL D N     1 
ATOM   11597 C  CA    . VAL D 2 204 ? 389.236 378.429 201.659 1.00 101.87 ? 204 VAL D CA    1 
ATOM   11598 C  C     . VAL D 2 204 ? 389.145 379.138 203.006 1.00 106.62 ? 204 VAL D C     1 
ATOM   11599 O  O     . VAL D 2 204 ? 390.089 379.083 203.802 1.00 114.34 ? 204 VAL D O     1 
ATOM   11600 C  CB    . VAL D 2 204 ? 388.809 376.941 201.748 1.00 107.21 ? 204 VAL D CB    1 
ATOM   11601 C  CG1   . VAL D 2 204 ? 387.656 376.719 202.746 1.00 110.63 ? 204 VAL D CG1   1 
ATOM   11602 C  CG2   . VAL D 2 204 ? 388.437 376.407 200.364 1.00 108.91 ? 204 VAL D CG2   1 
ATOM   11603 N  N     . ASP D 2 205 ? 388.014 379.807 203.259 1.00 106.53 ? 205 ASP D N     1 
ATOM   11604 C  CA    . ASP D 2 205 ? 387.798 380.584 204.478 1.00 106.58 ? 205 ASP D CA    1 
ATOM   11605 C  C     . ASP D 2 205 ? 386.487 380.181 205.139 1.00 112.05 ? 205 ASP D C     1 
ATOM   11606 O  O     . ASP D 2 205 ? 385.418 380.243 204.516 1.00 118.34 ? 205 ASP D O     1 
ATOM   11607 C  CB    . ASP D 2 205 ? 387.792 382.086 204.175 1.00 110.48 ? 205 ASP D CB    1 
ATOM   11608 C  CG    . ASP D 2 205 ? 387.694 382.943 205.425 1.00 117.01 ? 205 ASP D CG    1 
ATOM   11609 O  OD1   . ASP D 2 205 ? 387.816 382.409 206.548 1.00 116.71 ? 205 ASP D OD1   1 
ATOM   11610 O  OD2   . ASP D 2 205 ? 387.482 384.165 205.283 1.00 121.59 ? 205 ASP D OD2   1 
ATOM   11611 N  N     . ASN D 2 206 ? 386.578 379.819 206.422 1.00 109.35 ? 206 ASN D N     1 
ATOM   11612 C  CA    . ASN D 2 206 ? 385.397 379.431 207.184 1.00 109.74 ? 206 ASN D CA    1 
ATOM   11613 C  C     . ASN D 2 206 ? 384.411 380.584 207.304 1.00 112.81 ? 206 ASN D C     1 
ATOM   11614 O  O     . ASN D 2 206 ? 383.200 380.386 207.157 1.00 121.71 ? 206 ASN D O     1 
ATOM   11615 C  CB    . ASN D 2 206 ? 385.808 378.949 208.575 1.00 111.27 ? 206 ASN D CB    1 
ATOM   11616 C  CG    . ASN D 2 206 ? 386.765 377.775 208.531 1.00 111.06 ? 206 ASN D CG    1 
ATOM   11617 O  OD1   . ASN D 2 206 ? 387.902 377.871 208.989 1.00 115.03 ? 206 ASN D OD1   1 
ATOM   11618 N  ND2   . ASN D 2 206 ? 386.309 376.659 207.982 1.00 107.58 ? 206 ASN D ND2   1 
ATOM   11619 N  N     . GLU D 2 207 ? 384.909 381.791 207.585 1.00 114.79 ? 207 GLU D N     1 
ATOM   11620 C  CA    . GLU D 2 207 ? 384.027 382.947 207.723 1.00 115.50 ? 207 GLU D CA    1 
ATOM   11621 C  C     . GLU D 2 207 ? 383.318 383.260 206.414 1.00 117.77 ? 207 GLU D C     1 
ATOM   11622 O  O     . GLU D 2 207 ? 382.122 383.582 206.406 1.00 120.31 ? 207 GLU D O     1 
ATOM   11623 C  CB    . GLU D 2 207 ? 384.827 384.160 208.194 1.00 115.85 ? 207 GLU D CB    1 
ATOM   11624 C  CG    . GLU D 2 207 ? 383.974 385.249 208.816 1.00 123.74 ? 207 GLU D CG    1 
ATOM   11625 C  CD    . GLU D 2 207 ? 384.784 386.466 209.212 1.00 125.99 ? 207 GLU D CD    1 
ATOM   11626 O  OE1   . GLU D 2 207 ? 385.872 386.290 209.800 1.00 125.92 ? 207 GLU D OE1   1 
ATOM   11627 O  OE2   . GLU D 2 207 ? 384.334 387.597 208.935 1.00 122.45 ? 207 GLU D OE2   1 
ATOM   11628 N  N     . ALA D 2 208 ? 384.043 383.172 205.297 1.00 114.29 ? 208 ALA D N     1 
ATOM   11629 C  CA    . ALA D 2 208 ? 383.428 383.411 203.999 1.00 111.38 ? 208 ALA D CA    1 
ATOM   11630 C  C     . ALA D 2 208 ? 382.344 382.384 203.711 1.00 112.40 ? 208 ALA D C     1 
ATOM   11631 O  O     . ALA D 2 208 ? 381.277 382.731 203.191 1.00 115.78 ? 208 ALA D O     1 
ATOM   11632 C  CB    . ALA D 2 208 ? 384.489 383.387 202.901 1.00 116.77 ? 208 ALA D CB    1 
ATOM   11633 N  N     . ILE D 2 209 ? 382.589 381.114 204.050 1.00 113.48 ? 209 ILE D N     1 
ATOM   11634 C  CA    . ILE D 2 209 ? 381.563 380.111 203.769 1.00 111.26 ? 209 ILE D CA    1 
ATOM   11635 C  C     . ILE D 2 209 ? 380.363 380.295 204.696 1.00 111.75 ? 209 ILE D C     1 
ATOM   11636 O  O     . ILE D 2 209 ? 379.224 380.043 204.286 1.00 114.86 ? 209 ILE D O     1 
ATOM   11637 C  CB    . ILE D 2 209 ? 382.103 378.669 203.853 1.00 107.37 ? 209 ILE D CB    1 
ATOM   11638 C  CG1   . ILE D 2 209 ? 383.295 378.432 202.915 1.00 109.24 ? 209 ILE D CG1   1 
ATOM   11639 C  CG2   . ILE D 2 209 ? 380.996 377.693 203.423 1.00 108.05 ? 209 ILE D CG2   1 
ATOM   11640 C  CD1   . ILE D 2 209 ? 384.188 377.285 203.348 1.00 111.57 ? 209 ILE D CD1   1 
ATOM   11641 N  N     . TYR D 2 210 ? 380.584 380.705 205.953 1.00 108.39 ? 210 TYR D N     1 
ATOM   11642 C  CA    . TYR D 2 210 ? 379.457 381.026 206.831 1.00 102.41 ? 210 TYR D CA    1 
ATOM   11643 C  C     . TYR D 2 210 ? 378.615 382.147 206.246 1.00 104.61 ? 210 TYR D C     1 
ATOM   11644 O  O     . TYR D 2 210 ? 377.377 382.079 206.251 1.00 110.40 ? 210 TYR D O     1 
ATOM   11645 C  CB    . TYR D 2 210 ? 379.929 381.455 208.223 1.00 107.08 ? 210 TYR D CB    1 
ATOM   11646 C  CG    . TYR D 2 210 ? 380.781 380.486 209.006 1.00 106.87 ? 210 TYR D CG    1 
ATOM   11647 C  CD1   . TYR D 2 210 ? 380.688 379.116 208.821 1.00 106.50 ? 210 TYR D CD1   1 
ATOM   11648 C  CD2   . TYR D 2 210 ? 381.677 380.956 209.953 1.00 110.02 ? 210 TYR D CD2   1 
ATOM   11649 C  CE1   . TYR D 2 210 ? 381.469 378.250 209.555 1.00 111.62 ? 210 TYR D CE1   1 
ATOM   11650 C  CE2   . TYR D 2 210 ? 382.459 380.100 210.682 1.00 111.85 ? 210 TYR D CE2   1 
ATOM   11651 C  CZ    . TYR D 2 210 ? 382.352 378.751 210.480 1.00 114.18 ? 210 TYR D CZ    1 
ATOM   11652 O  OH    . TYR D 2 210 ? 383.141 377.909 211.215 1.00 116.95 ? 210 TYR D OH    1 
ATOM   11653 N  N     . ASP D 2 211 ? 379.273 383.195 205.749 1.00 112.00 ? 211 ASP D N     1 
ATOM   11654 C  CA    . ASP D 2 211 ? 378.542 384.302 205.151 1.00 114.42 ? 211 ASP D CA    1 
ATOM   11655 C  C     . ASP D 2 211 ? 377.781 383.853 203.913 1.00 116.92 ? 211 ASP D C     1 
ATOM   11656 O  O     . ASP D 2 211 ? 376.644 384.278 203.697 1.00 121.02 ? 211 ASP D O     1 
ATOM   11657 C  CB    . ASP D 2 211 ? 379.498 385.442 204.814 1.00 117.65 ? 211 ASP D CB    1 
ATOM   11658 C  CG    . ASP D 2 211 ? 379.845 386.282 206.022 1.00 124.39 ? 211 ASP D CG    1 
ATOM   11659 O  OD1   . ASP D 2 211 ? 379.730 385.772 207.156 1.00 125.92 ? 211 ASP D OD1   1 
ATOM   11660 O  OD2   . ASP D 2 211 ? 380.211 387.460 205.840 1.00 128.95 ? 211 ASP D OD2   1 
ATOM   11661 N  N     . ILE D 2 212 ? 378.382 382.981 203.100 1.00 115.95 ? 212 ILE D N     1 
ATOM   11662 C  CA    . ILE D 2 212 ? 377.694 382.470 201.914 1.00 115.29 ? 212 ILE D CA    1 
ATOM   11663 C  C     . ILE D 2 212 ? 376.459 381.672 202.318 1.00 118.72 ? 212 ILE D C     1 
ATOM   11664 O  O     . ILE D 2 212 ? 375.377 381.836 201.736 1.00 123.08 ? 212 ILE D O     1 
ATOM   11665 C  CB    . ILE D 2 212 ? 378.664 381.629 201.060 1.00 115.78 ? 212 ILE D CB    1 
ATOM   11666 C  CG1   . ILE D 2 212 ? 379.652 382.540 200.333 1.00 116.49 ? 212 ILE D CG1   1 
ATOM   11667 C  CG2   . ILE D 2 212 ? 377.917 380.771 200.028 1.00 117.04 ? 212 ILE D CG2   1 
ATOM   11668 C  CD1   . ILE D 2 212 ? 380.969 381.882 200.029 1.00 119.20 ? 212 ILE D CD1   1 
ATOM   11669 N  N     . CYS D 2 213 ? 376.604 380.800 203.320 1.00 121.73 ? 213 CYS D N     1 
ATOM   11670 C  CA    . CYS D 2 213 ? 375.494 379.963 203.762 1.00 121.35 ? 213 CYS D CA    1 
ATOM   11671 C  C     . CYS D 2 213 ? 374.351 380.809 204.303 1.00 121.60 ? 213 CYS D C     1 
ATOM   11672 O  O     . CYS D 2 213 ? 373.177 380.537 204.030 1.00 124.70 ? 213 CYS D O     1 
ATOM   11673 C  CB    . CYS D 2 213 ? 375.979 378.977 204.825 1.00 120.63 ? 213 CYS D CB    1 
ATOM   11674 S  SG    . CYS D 2 213 ? 376.929 377.585 204.179 1.00 119.97 ? 213 CYS D SG    1 
ATOM   11675 N  N     . ARG D 2 214 ? 374.677 381.842 205.079 1.00 123.58 ? 214 ARG D N     1 
ATOM   11676 C  CA    . ARG D 2 214 ? 373.636 382.728 205.585 1.00 124.29 ? 214 ARG D CA    1 
ATOM   11677 C  C     . ARG D 2 214 ? 372.987 383.512 204.448 1.00 124.80 ? 214 ARG D C     1 
ATOM   11678 O  O     . ARG D 2 214 ? 371.759 383.637 204.388 1.00 126.90 ? 214 ARG D O     1 
ATOM   11679 C  CB    . ARG D 2 214 ? 374.229 383.674 206.631 1.00 126.44 ? 214 ARG D CB    1 
ATOM   11680 C  CG    . ARG D 2 214 ? 373.208 384.556 207.392 1.00 124.38 ? 214 ARG D CG    1 
ATOM   11681 C  CD    . ARG D 2 214 ? 373.804 385.858 207.945 1.00 126.88 ? 214 ARG D CD    1 
ATOM   11682 N  NE    . ARG D 2 214 ? 375.241 385.762 208.214 1.00 134.62 ? 214 ARG D NE    1 
ATOM   11683 C  CZ    . ARG D 2 214 ? 376.162 386.689 207.964 1.00 133.88 ? 214 ARG D CZ    1 
ATOM   11684 N  NH1   . ARG D 2 214 ? 375.853 387.886 207.483 1.00 131.52 ? 214 ARG D NH1   1 
ATOM   11685 N  NH2   . ARG D 2 214 ? 377.438 386.411 208.215 1.00 133.58 ? 214 ARG D NH2   1 
ATOM   11686 N  N     . ARG D 2 215 ? 373.799 384.049 203.534 1.00 123.78 ? 215 ARG D N     1 
ATOM   11687 C  CA    . ARG D 2 215 ? 373.295 385.024 202.575 1.00 122.89 ? 215 ARG D CA    1 
ATOM   11688 C  C     . ARG D 2 215 ? 372.442 384.368 201.498 1.00 123.49 ? 215 ARG D C     1 
ATOM   11689 O  O     . ARG D 2 215 ? 371.368 384.878 201.157 1.00 124.41 ? 215 ARG D O     1 
ATOM   11690 C  CB    . ARG D 2 215 ? 374.467 385.767 201.937 1.00 123.33 ? 215 ARG D CB    1 
ATOM   11691 C  CG    . ARG D 2 215 ? 374.125 387.116 201.351 1.00 126.94 ? 215 ARG D CG    1 
ATOM   11692 C  CD    . ARG D 2 215 ? 375.174 387.540 200.322 1.00 127.34 ? 215 ARG D CD    1 
ATOM   11693 N  NE    . ARG D 2 215 ? 376.568 387.356 200.729 1.00 126.35 ? 215 ARG D NE    1 
ATOM   11694 C  CZ    . ARG D 2 215 ? 377.158 387.849 201.812 1.00 129.11 ? 215 ARG D CZ    1 
ATOM   11695 N  NH1   . ARG D 2 215 ? 376.547 388.697 202.625 1.00 129.06 ? 215 ARG D NH1   1 
ATOM   11696 N  NH2   . ARG D 2 215 ? 378.417 387.510 202.067 1.00 128.50 ? 215 ARG D NH2   1 
ATOM   11697 N  N     . ASN D 2 216 ? 372.889 383.227 200.966 1.00 116.19 ? 216 ASN D N     1 
ATOM   11698 C  CA    . ASN D 2 216 ? 372.319 382.653 199.751 1.00 116.42 ? 216 ASN D CA    1 
ATOM   11699 C  C     . ASN D 2 216 ? 371.456 381.435 200.072 1.00 120.33 ? 216 ASN D C     1 
ATOM   11700 O  O     . ASN D 2 216 ? 370.292 381.387 199.671 1.00 127.94 ? 216 ASN D O     1 
ATOM   11701 C  CB    . ASN D 2 216 ? 373.438 382.281 198.775 1.00 115.38 ? 216 ASN D CB    1 
ATOM   11702 C  CG    . ASN D 2 216 ? 374.014 383.489 198.048 1.00 123.60 ? 216 ASN D CG    1 
ATOM   11703 O  OD1   . ASN D 2 216 ? 373.372 384.533 197.930 1.00 129.23 ? 216 ASN D OD1   1 
ATOM   11704 N  ND2   . ASN D 2 216 ? 375.241 383.351 197.563 1.00 124.36 ? 216 ASN D ND2   1 
ATOM   11705 N  N     . LEU D 2 217 ? 371.992 380.452 200.788 1.00 116.40 ? 217 LEU D N     1 
ATOM   11706 C  CA    . LEU D 2 217 ? 371.240 379.237 201.070 1.00 119.06 ? 217 LEU D CA    1 
ATOM   11707 C  C     . LEU D 2 217 ? 370.149 379.456 202.125 1.00 122.51 ? 217 LEU D C     1 
ATOM   11708 O  O     . LEU D 2 217 ? 369.363 378.541 202.388 1.00 122.80 ? 217 LEU D O     1 
ATOM   11709 C  CB    . LEU D 2 217 ? 372.187 378.127 201.534 1.00 115.55 ? 217 LEU D CB    1 
ATOM   11710 C  CG    . LEU D 2 217 ? 373.050 377.249 200.622 1.00 120.27 ? 217 LEU D CG    1 
ATOM   11711 C  CD1   . LEU D 2 217 ? 372.303 376.753 199.407 1.00 125.60 ? 217 LEU D CD1   1 
ATOM   11712 C  CD2   . LEU D 2 217 ? 374.303 377.994 200.213 1.00 124.42 ? 217 LEU D CD2   1 
ATOM   11713 N  N     . ASP D 2 218 ? 370.114 380.631 202.773 1.00 139.98 ? 218 ASP D N     1 
ATOM   11714 C  CA    . ASP D 2 218 ? 369.038 381.004 203.704 1.00 140.26 ? 218 ASP D CA    1 
ATOM   11715 C  C     . ASP D 2 218 ? 368.930 380.049 204.889 1.00 140.02 ? 218 ASP D C     1 
ATOM   11716 O  O     . ASP D 2 218 ? 367.850 379.882 205.462 1.00 141.03 ? 218 ASP D O     1 
ATOM   11717 C  CB    . ASP D 2 218 ? 367.689 381.090 202.989 1.00 142.69 ? 218 ASP D CB    1 
ATOM   11718 C  CG    . ASP D 2 218 ? 367.714 382.032 201.810 1.00 145.04 ? 218 ASP D CG    1 
ATOM   11719 O  OD1   . ASP D 2 218 ? 367.948 383.241 202.022 1.00 141.63 ? 218 ASP D OD1   1 
ATOM   11720 O  OD2   . ASP D 2 218 ? 367.501 381.566 200.671 1.00 145.57 ? 218 ASP D OD2   1 
ATOM   11721 N  N     . ILE D 2 219 ? 370.107 379.600 205.353 1.00 133.72 ? 219 ILE D N     1 
ATOM   11722 C  CA    . ILE D 2 219 ? 370.208 378.814 206.619 1.00 132.38 ? 219 ILE D CA    1 
ATOM   11723 C  C     . ILE D 2 219 ? 370.768 379.814 207.638 1.00 131.44 ? 219 ILE D C     1 
ATOM   11724 O  O     . ILE D 2 219 ? 371.245 380.873 207.188 1.00 127.12 ? 219 ILE D O     1 
ATOM   11725 C  CB    . ILE D 2 219 ? 371.124 377.588 206.448 1.00 131.16 ? 219 ILE D CB    1 
ATOM   11726 C  CG1   . ILE D 2 219 ? 371.017 376.623 207.632 1.00 132.12 ? 219 ILE D CG1   1 
ATOM   11727 C  CG2   . ILE D 2 219 ? 372.561 378.014 206.199 1.00 130.36 ? 219 ILE D CG2   1 
ATOM   11728 C  CD1   . ILE D 2 219 ? 369.618 376.112 207.880 1.00 132.83 ? 219 ILE D CD1   1 
ATOM   11729 N  N     . GLU D 2 220 ? 370.729 379.530 208.944 1.00 144.55 ? 220 GLU D N     1 
ATOM   11730 C  CA    . GLU D 2 220 ? 371.144 380.569 209.932 1.00 142.82 ? 220 GLU D CA    1 
ATOM   11731 C  C     . GLU D 2 220 ? 372.282 380.091 210.843 1.00 142.21 ? 220 GLU D C     1 
ATOM   11732 O  O     . GLU D 2 220 ? 373.102 380.941 211.235 1.00 133.54 ? 220 GLU D O     1 
ATOM   11733 C  CB    . GLU D 2 220 ? 369.942 381.002 210.774 1.00 142.39 ? 220 GLU D CB    1 
ATOM   11734 C  CG    . GLU D 2 220 ? 370.232 382.163 211.710 1.00 141.93 ? 220 GLU D CG    1 
ATOM   11735 C  CD    . GLU D 2 220 ? 370.494 383.501 211.037 1.00 145.06 ? 220 GLU D CD    1 
ATOM   11736 O  OE1   . GLU D 2 220 ? 371.488 383.609 210.291 1.00 143.52 ? 220 GLU D OE1   1 
ATOM   11737 O  OE2   . GLU D 2 220 ? 369.699 384.435 211.261 1.00 147.28 ? 220 GLU D OE2   1 
ATOM   11738 N  N     . ARG D 2 221 ? 372.331 378.800 211.177 1.00 158.27 ? 221 ARG D N     1 
ATOM   11739 C  CA    . ARG D 2 221 ? 373.368 378.312 212.124 1.00 153.93 ? 221 ARG D CA    1 
ATOM   11740 C  C     . ARG D 2 221 ? 374.197 377.190 211.490 1.00 158.65 ? 221 ARG D C     1 
ATOM   11741 O  O     . ARG D 2 221 ? 374.191 376.077 212.044 1.00 157.14 ? 221 ARG D O     1 
ATOM   11742 C  CB    . ARG D 2 221 ? 372.704 377.832 213.418 1.00 150.48 ? 221 ARG D CB    1 
ATOM   11743 N  N     . PRO D 2 222 ? 374.844 377.356 210.306 1.00 154.00 ? 222 PRO D N     1 
ATOM   11744 C  CA    . PRO D 2 222 ? 375.569 376.248 209.649 1.00 154.47 ? 222 PRO D CA    1 
ATOM   11745 C  C     . PRO D 2 222 ? 376.633 375.530 210.494 1.00 150.54 ? 222 PRO D C     1 
ATOM   11746 O  O     . PRO D 2 222 ? 377.017 376.051 211.527 1.00 146.65 ? 222 PRO D O     1 
ATOM   11747 C  CB    . PRO D 2 222 ? 376.308 376.927 208.485 1.00 150.67 ? 222 PRO D CB    1 
ATOM   11748 C  CG    . PRO D 2 222 ? 375.429 378.092 208.129 1.00 147.66 ? 222 PRO D CG    1 
ATOM   11749 C  CD    . PRO D 2 222 ? 374.858 378.555 209.451 1.00 144.10 ? 222 PRO D CD    1 
ATOM   11750 N  N     . THR D 2 223 ? 377.102 374.371 210.016 1.00 138.43 ? 223 THR D N     1 
ATOM   11751 C  CA    . THR D 2 223 ? 378.140 373.588 210.744 1.00 129.92 ? 223 THR D CA    1 
ATOM   11752 C  C     . THR D 2 223 ? 379.201 373.096 209.752 1.00 131.54 ? 223 THR D C     1 
ATOM   11753 O  O     . THR D 2 223 ? 378.962 373.219 208.534 1.00 136.05 ? 223 THR D O     1 
ATOM   11754 C  CB    . THR D 2 223 ? 377.508 372.425 211.518 1.00 133.56 ? 223 THR D CB    1 
ATOM   11755 O  OG1   . THR D 2 223 ? 378.549 371.527 211.905 1.00 139.84 ? 223 THR D OG1   1 
ATOM   11756 C  CG2   . THR D 2 223 ? 376.471 371.675 210.712 1.00 134.26 ? 223 THR D CG2   1 
ATOM   11757 N  N     . TYR D 2 224 ? 380.307 372.535 210.251 1.00 91.91  ? 224 TYR D N     1 
ATOM   11758 C  CA    . TYR D 2 224 ? 381.424 372.085 209.372 1.00 91.06  ? 224 TYR D CA    1 
ATOM   11759 C  C     . TYR D 2 224 ? 380.890 371.195 208.248 1.00 94.49  ? 224 TYR D C     1 
ATOM   11760 O  O     . TYR D 2 224 ? 381.367 371.324 207.104 1.00 97.62  ? 224 TYR D O     1 
ATOM   11761 C  CB    . TYR D 2 224 ? 382.474 371.331 210.194 1.00 84.18  ? 224 TYR D CB    1 
ATOM   11762 C  CG    . TYR D 2 224 ? 383.420 372.206 211.005 1.00 90.04  ? 224 TYR D CG    1 
ATOM   11763 C  CD1   . TYR D 2 224 ? 384.377 371.643 211.841 1.00 91.94  ? 224 TYR D CD1   1 
ATOM   11764 C  CD2   . TYR D 2 224 ? 383.366 373.592 210.925 1.00 92.86  ? 224 TYR D CD2   1 
ATOM   11765 C  CE1   . TYR D 2 224 ? 385.242 372.430 212.580 1.00 91.41  ? 224 TYR D CE1   1 
ATOM   11766 C  CE2   . TYR D 2 224 ? 384.227 374.391 211.658 1.00 94.19  ? 224 TYR D CE2   1 
ATOM   11767 C  CZ    . TYR D 2 224 ? 385.168 373.808 212.488 1.00 94.05  ? 224 TYR D CZ    1 
ATOM   11768 O  OH    . TYR D 2 224 ? 386.020 374.589 213.215 1.00 100.24 ? 224 TYR D OH    1 
ATOM   11769 N  N     . THR D 2 225 ? 379.949 370.301 208.565 1.00 104.70 ? 225 THR D N     1 
ATOM   11770 C  CA    . THR D 2 225 ? 379.396 369.368 207.546 1.00 110.35 ? 225 THR D CA    1 
ATOM   11771 C  C     . THR D 2 225 ? 379.084 370.140 206.261 1.00 113.83 ? 225 THR D C     1 
ATOM   11772 O  O     . THR D 2 225 ? 379.671 369.801 205.215 1.00 120.17 ? 225 THR D O     1 
ATOM   11773 C  CB    . THR D 2 225 ? 378.149 368.653 208.078 1.00 113.89 ? 225 THR D CB    1 
ATOM   11774 O  OG1   . THR D 2 225 ? 377.086 369.605 208.153 1.00 112.87 ? 225 THR D OG1   1 
ATOM   11775 C  CG2   . THR D 2 225 ? 378.369 368.024 209.437 1.00 113.03 ? 225 THR D CG2   1 
ATOM   11776 N  N     . ASN D 2 226 ? 378.193 371.132 206.339 1.00 125.41 ? 226 ASN D N     1 
ATOM   11777 C  CA    . ASN D 2 226 ? 377.819 371.925 205.168 1.00 128.48 ? 226 ASN D CA    1 
ATOM   11778 C  C     . ASN D 2 226 ? 379.044 372.544 204.509 1.00 130.46 ? 226 ASN D C     1 
ATOM   11779 O  O     . ASN D 2 226 ? 379.139 372.587 203.275 1.00 135.82 ? 226 ASN D O     1 
ATOM   11780 C  CB    . ASN D 2 226 ? 376.824 373.018 205.559 1.00 126.76 ? 226 ASN D CB    1 
ATOM   11781 C  CG    . ASN D 2 226 ? 375.633 372.468 206.303 1.00 131.57 ? 226 ASN D CG    1 
ATOM   11782 O  OD1   . ASN D 2 226 ? 375.769 371.986 207.427 1.00 134.76 ? 226 ASN D OD1   1 
ATOM   11783 N  ND2   . ASN D 2 226 ? 374.464 372.545 205.699 1.00 133.01 ? 226 ASN D ND2   1 
ATOM   11784 N  N     . LEU D 2 227 ? 379.981 373.042 205.320 1.00 105.64 ? 227 LEU D N     1 
ATOM   11785 C  CA    . LEU D 2 227 ? 381.213 373.608 204.773 1.00 105.22 ? 227 LEU D CA    1 
ATOM   11786 C  C     . LEU D 2 227 ? 382.002 372.565 203.992 1.00 111.88 ? 227 LEU D C     1 
ATOM   11787 O  O     . LEU D 2 227 ? 382.484 372.831 202.883 1.00 115.27 ? 227 LEU D O     1 
ATOM   11788 C  CB    . LEU D 2 227 ? 382.074 374.169 205.904 1.00 107.28 ? 227 LEU D CB    1 
ATOM   11789 C  CG    . LEU D 2 227 ? 381.762 375.591 206.371 1.00 110.56 ? 227 LEU D CG    1 
ATOM   11790 C  CD1   . LEU D 2 227 ? 380.550 375.622 207.279 1.00 108.22 ? 227 LEU D CD1   1 
ATOM   11791 C  CD2   . LEU D 2 227 ? 382.957 376.235 207.063 1.00 114.37 ? 227 LEU D CD2   1 
ATOM   11792 N  N     . ASN D 2 228 ? 382.137 371.366 204.555 1.00 101.50 ? 228 ASN D N     1 
ATOM   11793 C  CA    . ASN D 2 228 ? 382.846 370.300 203.868 1.00 103.58 ? 228 ASN D CA    1 
ATOM   11794 C  C     . ASN D 2 228 ? 382.071 369.813 202.654 1.00 107.60 ? 228 ASN D C     1 
ATOM   11795 O  O     . ASN D 2 228 ? 382.680 369.368 201.684 1.00 115.18 ? 228 ASN D O     1 
ATOM   11796 C  CB    . ASN D 2 228 ? 383.118 369.150 204.833 1.00 97.64  ? 228 ASN D CB    1 
ATOM   11797 C  CG    . ASN D 2 228 ? 383.908 369.587 206.048 1.00 102.38 ? 228 ASN D CG    1 
ATOM   11798 O  OD1   . ASN D 2 228 ? 384.497 370.666 206.066 1.00 101.01 ? 228 ASN D OD1   1 
ATOM   11799 N  ND2   . ASN D 2 228 ? 383.926 368.745 207.074 1.00 106.62 ? 228 ASN D ND2   1 
ATOM   11800 N  N     . ARG D 2 229 ? 380.738 369.896 202.681 1.00 108.77 ? 229 ARG D N     1 
ATOM   11801 C  CA    . ARG D 2 229 ? 379.954 369.591 201.485 1.00 105.39 ? 229 ARG D CA    1 
ATOM   11802 C  C     . ARG D 2 229 ? 380.270 370.575 200.368 1.00 109.27 ? 229 ARG D C     1 
ATOM   11803 O  O     . ARG D 2 229 ? 380.432 370.180 199.209 1.00 112.75 ? 229 ARG D O     1 
ATOM   11804 C  CB    . ARG D 2 229 ? 378.450 369.619 201.794 1.00 104.49 ? 229 ARG D CB    1 
ATOM   11805 C  CG    . ARG D 2 229 ? 377.760 368.253 201.887 1.00 110.29 ? 229 ARG D CG    1 
ATOM   11806 C  CD    . ARG D 2 229 ? 377.951 367.609 203.248 1.00 113.56 ? 229 ARG D CD    1 
ATOM   11807 N  NE    . ARG D 2 229 ? 377.310 366.299 203.340 1.00 120.56 ? 229 ARG D NE    1 
ATOM   11808 C  CZ    . ARG D 2 229 ? 376.051 366.072 203.704 1.00 117.93 ? 229 ARG D CZ    1 
ATOM   11809 N  NH1   . ARG D 2 229 ? 375.209 367.057 203.985 1.00 110.74 ? 229 ARG D NH1   1 
ATOM   11810 N  NH2   . ARG D 2 229 ? 375.619 364.817 203.784 1.00 116.79 ? 229 ARG D NH2   1 
ATOM   11811 N  N     . LEU D 2 230 ? 380.362 371.864 200.700 1.00 104.31 ? 230 LEU D N     1 
ATOM   11812 C  CA    . LEU D 2 230 ? 380.705 372.862 199.687 1.00 104.71 ? 230 LEU D CA    1 
ATOM   11813 C  C     . LEU D 2 230 ? 382.122 372.651 199.157 1.00 108.12 ? 230 LEU D C     1 
ATOM   11814 O  O     . LEU D 2 230 ? 382.366 372.755 197.947 1.00 118.04 ? 230 LEU D O     1 
ATOM   11815 C  CB    . LEU D 2 230 ? 380.549 374.273 200.259 1.00 104.21 ? 230 LEU D CB    1 
ATOM   11816 C  CG    . LEU D 2 230 ? 379.208 374.957 199.979 1.00 109.34 ? 230 LEU D CG    1 
ATOM   11817 C  CD1   . LEU D 2 230 ? 378.049 374.226 200.641 1.00 109.70 ? 230 LEU D CD1   1 
ATOM   11818 C  CD2   . LEU D 2 230 ? 379.244 376.400 200.445 1.00 113.64 ? 230 LEU D CD2   1 
ATOM   11819 N  N     . ILE D 2 231 ? 383.067 372.342 200.045 1.00 99.48  ? 231 ILE D N     1 
ATOM   11820 C  CA    . ILE D 2 231 ? 384.438 372.092 199.605 1.00 101.69 ? 231 ILE D CA    1 
ATOM   11821 C  C     . ILE D 2 231 ? 384.497 370.821 198.759 1.00 101.32 ? 231 ILE D C     1 
ATOM   11822 O  O     . ILE D 2 231 ? 385.265 370.731 197.789 1.00 102.91 ? 231 ILE D O     1 
ATOM   11823 C  CB    . ILE D 2 231 ? 385.385 372.021 200.820 1.00 100.90 ? 231 ILE D CB    1 
ATOM   11824 C  CG1   . ILE D 2 231 ? 385.494 373.386 201.517 1.00 102.16 ? 231 ILE D CG1   1 
ATOM   11825 C  CG2   . ILE D 2 231 ? 386.776 371.564 200.398 1.00 101.83 ? 231 ILE D CG2   1 
ATOM   11826 C  CD1   . ILE D 2 231 ? 385.826 373.291 202.987 1.00 101.39 ? 231 ILE D CD1   1 
ATOM   11827 N  N     . SER D 2 232 ? 383.684 369.823 199.110 1.00 103.39 ? 232 SER D N     1 
ATOM   11828 C  CA    . SER D 2 232 ? 383.585 368.616 198.304 1.00 109.69 ? 232 SER D CA    1 
ATOM   11829 C  C     . SER D 2 232 ? 383.045 368.935 196.920 1.00 110.45 ? 232 SER D C     1 
ATOM   11830 O  O     . SER D 2 232 ? 383.509 368.378 195.922 1.00 114.60 ? 232 SER D O     1 
ATOM   11831 C  CB    . SER D 2 232 ? 382.693 367.592 199.002 1.00 115.06 ? 232 SER D CB    1 
ATOM   11832 O  OG    . SER D 2 232 ? 383.191 367.273 200.288 1.00 118.36 ? 232 SER D OG    1 
ATOM   11833 N  N     . GLN D 2 233 ? 382.054 369.824 196.845 1.00 103.50 ? 233 GLN D N     1 
ATOM   11834 C  CA    . GLN D 2 233 ? 381.538 370.251 195.550 1.00 105.96 ? 233 GLN D CA    1 
ATOM   11835 C  C     . GLN D 2 233 ? 382.626 370.937 194.734 1.00 107.49 ? 233 GLN D C     1 
ATOM   11836 O  O     . GLN D 2 233 ? 382.717 370.736 193.516 1.00 113.41 ? 233 GLN D O     1 
ATOM   11837 C  CB    . GLN D 2 233 ? 380.338 371.177 195.740 1.00 106.51 ? 233 GLN D CB    1 
ATOM   11838 C  CG    . GLN D 2 233 ? 379.083 370.477 196.252 1.00 106.53 ? 233 GLN D CG    1 
ATOM   11839 C  CD    . GLN D 2 233 ? 378.388 369.644 195.193 1.00 109.79 ? 233 GLN D CD    1 
ATOM   11840 O  OE1   . GLN D 2 233 ? 378.766 369.660 194.022 1.00 109.24 ? 233 GLN D OE1   1 
ATOM   11841 N  NE2   . GLN D 2 233 ? 377.364 368.906 195.603 1.00 109.90 ? 233 GLN D NE2   1 
ATOM   11842 N  N     . ILE D 2 234 ? 383.473 371.733 195.396 1.00 112.90 ? 234 ILE D N     1 
ATOM   11843 C  CA    . ILE D 2 234 ? 384.584 372.390 194.701 1.00 112.28 ? 234 ILE D CA    1 
ATOM   11844 C  C     . ILE D 2 234 ? 385.529 371.356 194.099 1.00 109.54 ? 234 ILE D C     1 
ATOM   11845 O  O     . ILE D 2 234 ? 385.870 371.422 192.910 1.00 111.24 ? 234 ILE D O     1 
ATOM   11846 C  CB    . ILE D 2 234 ? 385.332 373.344 195.656 1.00 111.75 ? 234 ILE D CB    1 
ATOM   11847 C  CG1   . ILE D 2 234 ? 384.514 374.611 195.927 1.00 113.32 ? 234 ILE D CG1   1 
ATOM   11848 C  CG2   . ILE D 2 234 ? 386.728 373.724 195.124 1.00 109.97 ? 234 ILE D CG2   1 
ATOM   11849 C  CD1   . ILE D 2 234 ? 384.496 375.640 194.785 1.00 118.41 ? 234 ILE D CD1   1 
ATOM   11850 N  N     . VAL D 2 235 ? 385.972 370.388 194.905 1.00 102.56 ? 235 VAL D N     1 
ATOM   11851 C  CA    . VAL D 2 235 ? 386.954 369.440 194.376 1.00 103.77 ? 235 VAL D CA    1 
ATOM   11852 C  C     . VAL D 2 235 ? 386.317 368.519 193.344 1.00 104.04 ? 235 VAL D C     1 
ATOM   11853 O  O     . VAL D 2 235 ? 386.987 368.081 192.403 1.00 111.87 ? 235 VAL D O     1 
ATOM   11854 C  CB    . VAL D 2 235 ? 387.646 368.637 195.495 1.00 99.59  ? 235 VAL D CB    1 
ATOM   11855 C  CG1   . VAL D 2 235 ? 388.232 369.571 196.519 1.00 105.17 ? 235 VAL D CG1   1 
ATOM   11856 C  CG2   . VAL D 2 235 ? 386.710 367.669 196.166 1.00 103.53 ? 235 VAL D CG2   1 
ATOM   11857 N  N     . SER D 2 236 ? 385.035 368.186 193.509 1.00 110.46 ? 236 SER D N     1 
ATOM   11858 C  CA    . SER D 2 236 ? 384.356 367.375 192.509 1.00 117.02 ? 236 SER D CA    1 
ATOM   11859 C  C     . SER D 2 236 ? 384.266 368.113 191.184 1.00 116.77 ? 236 SER D C     1 
ATOM   11860 O  O     . SER D 2 236 ? 384.492 367.520 190.125 1.00 117.99 ? 236 SER D O     1 
ATOM   11861 C  CB    . SER D 2 236 ? 382.961 366.993 192.998 1.00 122.10 ? 236 SER D CB    1 
ATOM   11862 O  OG    . SER D 2 236 ? 382.136 368.138 193.103 1.00 122.13 ? 236 SER D OG    1 
ATOM   11863 N  N     . SER D 2 237 ? 383.952 369.411 191.221 1.00 116.72 ? 237 SER D N     1 
ATOM   11864 C  CA    . SER D 2 237 ? 383.953 370.202 189.996 1.00 117.02 ? 237 SER D CA    1 
ATOM   11865 C  C     . SER D 2 237 ? 385.348 370.272 189.392 1.00 119.30 ? 237 SER D C     1 
ATOM   11866 O  O     . SER D 2 237 ? 385.503 370.283 188.165 1.00 123.92 ? 237 SER D O     1 
ATOM   11867 C  CB    . SER D 2 237 ? 383.421 371.606 190.280 1.00 112.98 ? 237 SER D CB    1 
ATOM   11868 O  OG    . SER D 2 237 ? 382.138 371.551 190.878 1.00 119.42 ? 237 SER D OG    1 
ATOM   11869 N  N     . ILE D 2 238 ? 386.378 370.321 190.237 1.00 109.32 ? 238 ILE D N     1 
ATOM   11870 C  CA    . ILE D 2 238 ? 387.744 370.432 189.730 1.00 104.24 ? 238 ILE D CA    1 
ATOM   11871 C  C     . ILE D 2 238 ? 388.168 369.130 189.053 1.00 108.75 ? 238 ILE D C     1 
ATOM   11872 O  O     . ILE D 2 238 ? 388.806 369.142 187.994 1.00 110.47 ? 238 ILE D O     1 
ATOM   11873 C  CB    . ILE D 2 238 ? 388.697 370.845 190.868 1.00 101.33 ? 238 ILE D CB    1 
ATOM   11874 C  CG1   . ILE D 2 238 ? 388.612 372.363 191.058 1.00 112.21 ? 238 ILE D CG1   1 
ATOM   11875 C  CG2   . ILE D 2 238 ? 390.160 370.479 190.578 1.00 103.16 ? 238 ILE D CG2   1 
ATOM   11876 C  CD1   . ILE D 2 238 ? 388.971 372.865 192.439 1.00 115.78 ? 238 ILE D CD1   1 
ATOM   11877 N  N     . THR D 2 239 ? 387.815 367.992 189.650 1.00 115.42 ? 239 THR D N     1 
ATOM   11878 C  CA    . THR D 2 239 ? 388.261 366.683 189.183 1.00 107.66 ? 239 THR D CA    1 
ATOM   11879 C  C     . THR D 2 239 ? 387.320 366.032 188.171 1.00 110.52 ? 239 THR D C     1 
ATOM   11880 O  O     . THR D 2 239 ? 387.686 365.001 187.585 1.00 114.51 ? 239 THR D O     1 
ATOM   11881 C  CB    . THR D 2 239 ? 388.436 365.740 190.379 1.00 106.83 ? 239 THR D CB    1 
ATOM   11882 O  OG1   . THR D 2 239 ? 387.253 365.760 191.187 1.00 116.44 ? 239 THR D OG1   1 
ATOM   11883 C  CG2   . THR D 2 239 ? 389.638 366.146 191.227 1.00 109.61 ? 239 THR D CG2   1 
ATOM   11884 N  N     . ALA D 2 240 ? 386.129 366.599 187.947 1.00 112.65 ? 240 ALA D N     1 
ATOM   11885 C  CA    . ALA D 2 240 ? 385.185 365.995 187.017 1.00 112.17 ? 240 ALA D CA    1 
ATOM   11886 C  C     . ALA D 2 240 ? 385.715 365.981 185.593 1.00 109.68 ? 240 ALA D C     1 
ATOM   11887 O  O     . ALA D 2 240 ? 385.310 365.135 184.795 1.00 113.37 ? 240 ALA D O     1 
ATOM   11888 C  CB    . ALA D 2 240 ? 383.851 366.736 187.071 1.00 110.88 ? 240 ALA D CB    1 
ATOM   11889 N  N     . SER D 2 241 ? 386.604 366.908 185.245 1.00 111.98 ? 241 SER D N     1 
ATOM   11890 C  CA    . SER D 2 241 ? 387.211 366.855 183.922 1.00 116.48 ? 241 SER D CA    1 
ATOM   11891 C  C     . SER D 2 241 ? 388.123 365.643 183.782 1.00 117.45 ? 241 SER D C     1 
ATOM   11892 O  O     . SER D 2 241 ? 388.147 364.998 182.728 1.00 116.99 ? 241 SER D O     1 
ATOM   11893 C  CB    . SER D 2 241 ? 387.975 368.142 183.646 1.00 117.79 ? 241 SER D CB    1 
ATOM   11894 O  OG    . SER D 2 241 ? 387.089 369.148 183.189 1.00 115.93 ? 241 SER D OG    1 
ATOM   11895 N  N     . LEU D 2 242 ? 388.886 365.322 184.829 1.00 122.40 ? 242 LEU D N     1 
ATOM   11896 C  CA    . LEU D 2 242 ? 389.692 364.106 184.800 1.00 117.72 ? 242 LEU D CA    1 
ATOM   11897 C  C     . LEU D 2 242 ? 388.812 362.867 184.737 1.00 117.58 ? 242 LEU D C     1 
ATOM   11898 O  O     . LEU D 2 242 ? 389.087 361.942 183.964 1.00 125.62 ? 242 LEU D O     1 
ATOM   11899 C  CB    . LEU D 2 242 ? 390.602 364.035 186.026 1.00 117.29 ? 242 LEU D CB    1 
ATOM   11900 C  CG    . LEU D 2 242 ? 391.900 364.844 185.995 1.00 126.29 ? 242 LEU D CG    1 
ATOM   11901 C  CD1   . LEU D 2 242 ? 392.474 364.963 187.396 1.00 127.02 ? 242 LEU D CD1   1 
ATOM   11902 C  CD2   . LEU D 2 242 ? 392.919 364.204 185.059 1.00 124.59 ? 242 LEU D CD2   1 
ATOM   11903 N  N     . ARG D 2 243 ? 387.746 362.833 185.535 1.00 115.62 ? 243 ARG D N     1 
ATOM   11904 C  CA    . ARG D 2 243 ? 386.956 361.607 185.625 1.00 118.66 ? 243 ARG D CA    1 
ATOM   11905 C  C     . ARG D 2 243 ? 386.003 361.459 184.440 1.00 120.15 ? 243 ARG D C     1 
ATOM   11906 O  O     . ARG D 2 243 ? 386.160 360.553 183.615 1.00 125.19 ? 243 ARG D O     1 
ATOM   11907 C  CB    . ARG D 2 243 ? 386.180 361.570 186.943 1.00 114.61 ? 243 ARG D CB    1 
ATOM   11908 C  CG    . ARG D 2 243 ? 387.053 361.459 188.183 1.00 117.43 ? 243 ARG D CG    1 
ATOM   11909 C  CD    . ARG D 2 243 ? 386.559 362.360 189.294 1.00 118.26 ? 243 ARG D CD    1 
ATOM   11910 N  NE    . ARG D 2 243 ? 385.182 362.052 189.656 1.00 120.28 ? 243 ARG D NE    1 
ATOM   11911 C  CZ    . ARG D 2 243 ? 384.419 362.781 190.460 1.00 122.51 ? 243 ARG D CZ    1 
ATOM   11912 N  NH1   . ARG D 2 243 ? 384.851 363.907 191.009 1.00 118.15 ? 243 ARG D NH1   1 
ATOM   11913 N  NH2   . ARG D 2 243 ? 383.184 362.368 190.722 1.00 126.45 ? 243 ARG D NH2   1 
ATOM   11914 N  N     . PHE D 2 244 ? 385.030 362.356 184.324 1.00 111.35 ? 244 PHE D N     1 
ATOM   11915 C  CA    . PHE D 2 244 ? 384.026 362.274 183.274 1.00 108.43 ? 244 PHE D CA    1 
ATOM   11916 C  C     . PHE D 2 244 ? 384.534 362.905 181.985 1.00 114.12 ? 244 PHE D C     1 
ATOM   11917 O  O     . PHE D 2 244 ? 385.408 363.776 181.994 1.00 118.93 ? 244 PHE D O     1 
ATOM   11918 C  CB    . PHE D 2 244 ? 382.737 362.977 183.702 1.00 104.82 ? 244 PHE D CB    1 
ATOM   11919 C  CG    . PHE D 2 244 ? 382.240 362.571 185.058 1.00 104.11 ? 244 PHE D CG    1 
ATOM   11920 C  CD1   . PHE D 2 244 ? 381.427 361.462 185.207 1.00 106.21 ? 244 PHE D CD1   1 
ATOM   11921 C  CD2   . PHE D 2 244 ? 382.577 363.303 186.182 1.00 115.43 ? 244 PHE D CD2   1 
ATOM   11922 C  CE1   . PHE D 2 244 ? 380.963 361.090 186.451 1.00 111.57 ? 244 PHE D CE1   1 
ATOM   11923 C  CE2   . PHE D 2 244 ? 382.119 362.933 187.428 1.00 116.81 ? 244 PHE D CE2   1 
ATOM   11924 C  CZ    . PHE D 2 244 ? 381.311 361.826 187.563 1.00 112.53 ? 244 PHE D CZ    1 
ATOM   11925 N  N     . ASP D 2 245 ? 383.973 362.453 180.867 1.00 121.63 ? 245 ASP D N     1 
ATOM   11926 C  CA    . ASP D 2 245 ? 384.258 363.071 179.582 1.00 124.33 ? 245 ASP D CA    1 
ATOM   11927 C  C     . ASP D 2 245 ? 383.549 364.419 179.478 1.00 123.62 ? 245 ASP D C     1 
ATOM   11928 O  O     . ASP D 2 245 ? 382.582 364.700 180.191 1.00 124.67 ? 245 ASP D O     1 
ATOM   11929 C  CB    . ASP D 2 245 ? 383.822 362.158 178.438 1.00 124.64 ? 245 ASP D CB    1 
ATOM   11930 C  CG    . ASP D 2 245 ? 382.321 361.976 178.380 1.00 127.81 ? 245 ASP D CG    1 
ATOM   11931 O  OD1   . ASP D 2 245 ? 381.677 362.021 179.449 1.00 129.12 ? 245 ASP D OD1   1 
ATOM   11932 O  OD2   . ASP D 2 245 ? 381.785 361.790 177.268 1.00 127.88 ? 245 ASP D OD2   1 
ATOM   11933 N  N     . GLY D 2 246 ? 384.044 365.259 178.571 1.00 104.84 ? 246 GLY D N     1 
ATOM   11934 C  CA    . GLY D 2 246 ? 383.493 366.593 178.422 1.00 106.04 ? 246 GLY D CA    1 
ATOM   11935 C  C     . GLY D 2 246 ? 383.886 367.218 177.104 1.00 106.14 ? 246 GLY D C     1 
ATOM   11936 O  O     . GLY D 2 246 ? 384.773 366.737 176.395 1.00 105.83 ? 246 GLY D O     1 
ATOM   11937 N  N     . ALA D 2 247 ? 383.200 368.318 176.785 1.00 102.57 ? 247 ALA D N     1 
ATOM   11938 C  CA    . ALA D 2 247 ? 383.473 369.027 175.539 1.00 103.58 ? 247 ALA D CA    1 
ATOM   11939 C  C     . ALA D 2 247 ? 384.846 369.685 175.564 1.00 104.69 ? 247 ALA D C     1 
ATOM   11940 O  O     . ALA D 2 247 ? 385.531 369.736 174.536 1.00 111.12 ? 247 ALA D O     1 
ATOM   11941 C  CB    . ALA D 2 247 ? 382.386 370.069 175.283 1.00 104.22 ? 247 ALA D CB    1 
ATOM   11942 N  N     . LEU D 2 248 ? 385.256 370.202 176.723 1.00 107.45 ? 248 LEU D N     1 
ATOM   11943 C  CA    . LEU D 2 248 ? 386.552 370.856 176.908 1.00 110.64 ? 248 LEU D CA    1 
ATOM   11944 C  C     . LEU D 2 248 ? 387.160 370.310 178.195 1.00 113.62 ? 248 LEU D C     1 
ATOM   11945 O  O     . LEU D 2 248 ? 386.774 370.721 179.293 1.00 115.40 ? 248 LEU D O     1 
ATOM   11946 C  CB    . LEU D 2 248 ? 386.401 372.373 176.963 1.00 108.49 ? 248 LEU D CB    1 
ATOM   11947 C  CG    . LEU D 2 248 ? 386.751 373.129 175.680 1.00 109.30 ? 248 LEU D CG    1 
ATOM   11948 C  CD1   . LEU D 2 248 ? 386.144 374.521 175.702 1.00 111.02 ? 248 LEU D CD1   1 
ATOM   11949 C  CD2   . LEU D 2 248 ? 388.259 373.211 175.492 1.00 110.00 ? 248 LEU D CD2   1 
ATOM   11950 N  N     . ASN D 2 249 ? 388.112 369.392 178.053 1.00 103.48 ? 249 ASN D N     1 
ATOM   11951 C  CA    . ASN D 2 249 ? 388.735 368.716 179.181 1.00 101.44 ? 249 ASN D CA    1 
ATOM   11952 C  C     . ASN D 2 249 ? 389.987 369.459 179.623 1.00 108.12 ? 249 ASN D C     1 
ATOM   11953 O  O     . ASN D 2 249 ? 390.723 370.010 178.799 1.00 110.57 ? 249 ASN D O     1 
ATOM   11954 C  CB    . ASN D 2 249 ? 389.082 367.271 178.821 1.00 103.56 ? 249 ASN D CB    1 
ATOM   11955 C  CG    . ASN D 2 249 ? 387.853 366.394 178.687 1.00 107.77 ? 249 ASN D CG    1 
ATOM   11956 O  OD1   . ASN D 2 249 ? 386.916 366.495 179.478 1.00 101.37 ? 249 ASN D OD1   1 
ATOM   11957 N  ND2   . ASN D 2 249 ? 387.849 365.529 177.681 1.00 112.92 ? 249 ASN D ND2   1 
ATOM   11958 N  N     . VAL D 2 250 ? 390.214 369.465 180.934 1.00 119.15 ? 250 VAL D N     1 
ATOM   11959 C  CA    . VAL D 2 250 ? 391.292 370.201 181.583 1.00 123.80 ? 250 VAL D CA    1 
ATOM   11960 C  C     . VAL D 2 250 ? 391.942 369.302 182.627 1.00 122.63 ? 250 VAL D C     1 
ATOM   11961 O  O     . VAL D 2 250 ? 391.249 368.573 183.346 1.00 113.89 ? 250 VAL D O     1 
ATOM   11962 C  CB    . VAL D 2 250 ? 390.771 371.515 182.212 1.00 120.55 ? 250 VAL D CB    1 
ATOM   11963 C  CG1   . VAL D 2 250 ? 390.172 372.405 181.142 1.00 122.63 ? 250 VAL D CG1   1 
ATOM   11964 C  CG2   . VAL D 2 250 ? 389.688 371.249 183.265 1.00 118.94 ? 250 VAL D CG2   1 
ATOM   11965 N  N     . ASP D 2 251 ? 393.270 369.359 182.708 1.00 147.20 ? 251 ASP D N     1 
ATOM   11966 C  CA    . ASP D 2 251 ? 394.078 368.544 183.607 1.00 145.03 ? 251 ASP D CA    1 
ATOM   11967 C  C     . ASP D 2 251 ? 394.785 369.429 184.628 1.00 146.70 ? 251 ASP D C     1 
ATOM   11968 O  O     . ASP D 2 251 ? 394.772 370.659 184.542 1.00 149.05 ? 251 ASP D O     1 
ATOM   11969 C  CB    . ASP D 2 251 ? 395.099 367.720 182.813 1.00 145.27 ? 251 ASP D CB    1 
ATOM   11970 C  CG    . ASP D 2 251 ? 394.449 366.637 181.978 1.00 148.79 ? 251 ASP D CG    1 
ATOM   11971 O  OD1   . ASP D 2 251 ? 393.296 366.830 181.542 1.00 151.12 ? 251 ASP D OD1   1 
ATOM   11972 O  OD2   . ASP D 2 251 ? 395.093 365.590 181.758 1.00 147.80 ? 251 ASP D OD2   1 
ATOM   11973 N  N     . LEU D 2 252 ? 395.423 368.778 185.604 1.00 129.26 ? 252 LEU D N     1 
ATOM   11974 C  CA    . LEU D 2 252 ? 396.076 369.513 186.686 1.00 130.50 ? 252 LEU D CA    1 
ATOM   11975 C  C     . LEU D 2 252 ? 397.322 370.240 186.192 1.00 130.17 ? 252 LEU D C     1 
ATOM   11976 O  O     . LEU D 2 252 ? 397.649 371.332 186.677 1.00 133.09 ? 252 LEU D O     1 
ATOM   11977 C  CB    . LEU D 2 252 ? 396.429 368.560 187.829 1.00 127.12 ? 252 LEU D CB    1 
ATOM   11978 C  CG    . LEU D 2 252 ? 395.365 367.544 188.263 1.00 124.44 ? 252 LEU D CG    1 
ATOM   11979 C  CD1   . LEU D 2 252 ? 395.821 366.810 189.514 1.00 127.17 ? 252 LEU D CD1   1 
ATOM   11980 C  CD2   . LEU D 2 252 ? 394.006 368.203 188.482 1.00 123.21 ? 252 LEU D CD2   1 
ATOM   11981 N  N     . THR D 2 253 ? 398.040 369.647 185.236 1.00 129.91 ? 253 THR D N     1 
ATOM   11982 C  CA    . THR D 2 253 ? 399.183 370.334 184.645 1.00 134.52 ? 253 THR D CA    1 
ATOM   11983 C  C     . THR D 2 253 ? 398.737 371.605 183.934 1.00 135.18 ? 253 THR D C     1 
ATOM   11984 O  O     . THR D 2 253 ? 399.395 372.650 184.029 1.00 138.48 ? 253 THR D O     1 
ATOM   11985 C  CB    . THR D 2 253 ? 399.911 369.399 183.680 1.00 135.11 ? 253 THR D CB    1 
ATOM   11986 O  OG1   . THR D 2 253 ? 400.367 368.239 184.387 1.00 133.85 ? 253 THR D OG1   1 
ATOM   11987 C  CG2   . THR D 2 253 ? 401.106 370.099 183.045 1.00 135.11 ? 253 THR D CG2   1 
ATOM   11988 N  N     . GLU D 2 254 ? 397.604 371.541 183.234 1.00 117.85 ? 254 GLU D N     1 
ATOM   11989 C  CA    . GLU D 2 254 ? 397.079 372.735 182.585 1.00 121.79 ? 254 GLU D CA    1 
ATOM   11990 C  C     . GLU D 2 254 ? 396.542 373.732 183.604 1.00 114.59 ? 254 GLU D C     1 
ATOM   11991 O  O     . GLU D 2 254 ? 396.591 374.942 183.359 1.00 111.50 ? 254 GLU D O     1 
ATOM   11992 C  CB    . GLU D 2 254 ? 395.998 372.352 181.571 1.00 117.54 ? 254 GLU D CB    1 
ATOM   11993 C  CG    . GLU D 2 254 ? 396.401 371.235 180.594 1.00 123.50 ? 254 GLU D CG    1 
ATOM   11994 C  CD    . GLU D 2 254 ? 397.720 371.505 179.875 1.00 121.49 ? 254 GLU D CD    1 
ATOM   11995 O  OE1   . GLU D 2 254 ? 398.035 372.688 179.620 1.00 110.94 ? 254 GLU D OE1   1 
ATOM   11996 O  OE2   . GLU D 2 254 ? 398.445 370.535 179.573 1.00 107.36 ? 254 GLU D OE2   1 
ATOM   11997 N  N     . PHE D 2 255 ? 396.048 373.255 184.752 1.00 111.77 ? 255 PHE D N     1 
ATOM   11998 C  CA    . PHE D 2 255 ? 395.720 374.171 185.843 1.00 113.81 ? 255 PHE D CA    1 
ATOM   11999 C  C     . PHE D 2 255 ? 396.945 374.941 186.304 1.00 120.23 ? 255 PHE D C     1 
ATOM   12000 O  O     . PHE D 2 255 ? 396.874 376.154 186.516 1.00 123.76 ? 255 PHE D O     1 
ATOM   12001 C  CB    . PHE D 2 255 ? 395.120 373.423 187.032 1.00 113.01 ? 255 PHE D CB    1 
ATOM   12002 C  CG    . PHE D 2 255 ? 393.640 373.256 186.962 1.00 113.03 ? 255 PHE D CG    1 
ATOM   12003 C  CD1   . PHE D 2 255 ? 393.028 372.836 185.802 1.00 120.04 ? 255 PHE D CD1   1 
ATOM   12004 C  CD2   . PHE D 2 255 ? 392.858 373.518 188.070 1.00 114.72 ? 255 PHE D CD2   1 
ATOM   12005 C  CE1   . PHE D 2 255 ? 391.674 372.687 185.746 1.00 122.64 ? 255 PHE D CE1   1 
ATOM   12006 C  CE2   . PHE D 2 255 ? 391.495 373.367 188.016 1.00 120.98 ? 255 PHE D CE2   1 
ATOM   12007 C  CZ    . PHE D 2 255 ? 390.903 372.949 186.851 1.00 123.33 ? 255 PHE D CZ    1 
ATOM   12008 N  N     . GLN D 2 256 ? 398.076 374.253 186.471 1.00 123.85 ? 256 GLN D N     1 
ATOM   12009 C  CA    . GLN D 2 256 ? 399.307 374.954 186.831 1.00 118.84 ? 256 GLN D CA    1 
ATOM   12010 C  C     . GLN D 2 256 ? 399.686 375.972 185.763 1.00 124.76 ? 256 GLN D C     1 
ATOM   12011 O  O     . GLN D 2 256 ? 399.894 377.156 186.069 1.00 127.45 ? 256 GLN D O     1 
ATOM   12012 C  CB    . GLN D 2 256 ? 400.453 373.963 187.027 1.00 122.25 ? 256 GLN D CB    1 
ATOM   12013 C  CG    . GLN D 2 256 ? 400.253 372.973 188.149 1.00 126.10 ? 256 GLN D CG    1 
ATOM   12014 C  CD    . GLN D 2 256 ? 401.294 371.874 188.130 1.00 130.45 ? 256 GLN D CD    1 
ATOM   12015 O  OE1   . GLN D 2 256 ? 400.964 370.694 188.038 1.00 133.11 ? 256 GLN D OE1   1 
ATOM   12016 N  NE2   . GLN D 2 256 ? 402.562 372.258 188.211 1.00 127.42 ? 256 GLN D NE2   1 
ATOM   12017 N  N     . THR D 2 257 ? 399.694 375.536 184.499 1.00 120.35 ? 257 THR D N     1 
ATOM   12018 C  CA    . THR D 2 257 ? 400.146 376.379 183.395 1.00 117.83 ? 257 THR D CA    1 
ATOM   12019 C  C     . THR D 2 257 ? 399.278 377.621 183.240 1.00 117.31 ? 257 THR D C     1 
ATOM   12020 O  O     . THR D 2 257 ? 399.789 378.706 182.941 1.00 120.82 ? 257 THR D O     1 
ATOM   12021 C  CB    . THR D 2 257 ? 400.148 375.571 182.096 1.00 116.82 ? 257 THR D CB    1 
ATOM   12022 O  OG1   . THR D 2 257 ? 400.988 374.420 182.247 1.00 118.38 ? 257 THR D OG1   1 
ATOM   12023 C  CG2   . THR D 2 257 ? 400.648 376.413 180.930 1.00 120.44 ? 257 THR D CG2   1 
ATOM   12024 N  N     . ASN D 2 258 ? 397.969 377.487 183.444 1.00 104.43 ? 258 ASN D N     1 
ATOM   12025 C  CA    . ASN D 2 258 ? 397.061 378.615 183.301 1.00 105.93 ? 258 ASN D CA    1 
ATOM   12026 C  C     . ASN D 2 258 ? 397.045 379.505 184.539 1.00 106.56 ? 258 ASN D C     1 
ATOM   12027 O  O     . ASN D 2 258 ? 397.238 380.719 184.431 1.00 111.31 ? 258 ASN D O     1 
ATOM   12028 C  CB    . ASN D 2 258 ? 395.650 378.107 182.998 1.00 102.39 ? 258 ASN D CB    1 
ATOM   12029 C  CG    . ASN D 2 258 ? 395.507 377.608 181.576 1.00 108.46 ? 258 ASN D CG    1 
ATOM   12030 O  OD1   . ASN D 2 258 ? 395.369 378.396 180.642 1.00 115.67 ? 258 ASN D OD1   1 
ATOM   12031 N  ND2   . ASN D 2 258 ? 395.543 376.293 181.403 1.00 108.24 ? 258 ASN D ND2   1 
ATOM   12032 N  N     . LEU D 2 259 ? 396.819 378.927 185.720 1.00 99.16  ? 259 LEU D N     1 
ATOM   12033 C  CA    . LEU D 2 259 ? 396.570 379.737 186.904 1.00 98.82  ? 259 LEU D CA    1 
ATOM   12034 C  C     . LEU D 2 259 ? 397.837 380.355 187.481 1.00 102.75 ? 259 LEU D C     1 
ATOM   12035 O  O     . LEU D 2 259 ? 397.744 381.388 188.153 1.00 105.98 ? 259 LEU D O     1 
ATOM   12036 C  CB    . LEU D 2 259 ? 395.875 378.908 187.990 1.00 100.38 ? 259 LEU D CB    1 
ATOM   12037 C  CG    . LEU D 2 259 ? 394.382 378.562 187.871 1.00 99.43  ? 259 LEU D CG    1 
ATOM   12038 C  CD1   . LEU D 2 259 ? 393.529 379.796 188.128 1.00 103.64 ? 259 LEU D CD1   1 
ATOM   12039 C  CD2   . LEU D 2 259 ? 393.997 377.931 186.539 1.00 101.43 ? 259 LEU D CD2   1 
ATOM   12040 N  N     . VAL D 2 260 ? 399.009 379.763 187.246 1.00 102.94 ? 260 VAL D N     1 
ATOM   12041 C  CA    . VAL D 2 260 ? 400.239 380.206 187.908 1.00 100.53 ? 260 VAL D CA    1 
ATOM   12042 C  C     . VAL D 2 260 ? 401.038 381.082 186.944 1.00 104.28 ? 260 VAL D C     1 
ATOM   12043 O  O     . VAL D 2 260 ? 401.676 380.539 186.030 1.00 114.78 ? 260 VAL D O     1 
ATOM   12044 C  CB    . VAL D 2 260 ? 401.066 378.998 188.380 1.00 104.08 ? 260 VAL D CB    1 
ATOM   12045 C  CG1   . VAL D 2 260 ? 402.311 379.452 189.142 1.00 103.16 ? 260 VAL D CG1   1 
ATOM   12046 C  CG2   . VAL D 2 260 ? 400.203 378.063 189.236 1.00 109.80 ? 260 VAL D CG2   1 
ATOM   12047 N  N     . PRO D 2 261 ? 401.058 382.437 187.089 1.00 94.19  ? 261 PRO D N     1 
ATOM   12048 C  CA    . PRO D 2 261 ? 401.876 383.245 186.171 1.00 99.43  ? 261 PRO D CA    1 
ATOM   12049 C  C     . PRO D 2 261 ? 403.356 383.242 186.517 1.00 101.70 ? 261 PRO D C     1 
ATOM   12050 O  O     . PRO D 2 261 ? 404.205 383.263 185.620 1.00 101.18 ? 261 PRO D O     1 
ATOM   12051 C  CB    . PRO D 2 261 ? 401.278 384.647 186.319 1.00 99.05  ? 261 PRO D CB    1 
ATOM   12052 C  CG    . PRO D 2 261 ? 400.800 384.684 187.704 1.00 96.34  ? 261 PRO D CG    1 
ATOM   12053 C  CD    . PRO D 2 261 ? 400.270 383.307 187.984 1.00 98.21  ? 261 PRO D CD    1 
ATOM   12054 N  N     . TYR D 2 262 ? 403.667 383.228 187.807 1.00 99.39  ? 262 TYR D N     1 
ATOM   12055 C  CA    . TYR D 2 262 ? 405.019 383.189 188.340 1.00 93.63  ? 262 TYR D CA    1 
ATOM   12056 C  C     . TYR D 2 262 ? 405.085 382.101 189.399 1.00 100.88 ? 262 TYR D C     1 
ATOM   12057 O  O     . TYR D 2 262 ? 404.052 381.729 189.965 1.00 106.68 ? 262 TYR D O     1 
ATOM   12058 C  CB    . TYR D 2 262 ? 405.420 384.544 188.942 1.00 92.62  ? 262 TYR D CB    1 
ATOM   12059 C  CG    . TYR D 2 262 ? 405.288 385.696 187.975 1.00 96.99  ? 262 TYR D CG    1 
ATOM   12060 C  CD1   . TYR D 2 262 ? 406.245 385.913 186.995 1.00 100.99 ? 262 TYR D CD1   1 
ATOM   12061 C  CD2   . TYR D 2 262 ? 404.210 386.565 188.040 1.00 102.15 ? 262 TYR D CD2   1 
ATOM   12062 C  CE1   . TYR D 2 262 ? 406.132 386.963 186.107 1.00 101.77 ? 262 TYR D CE1   1 
ATOM   12063 C  CE2   . TYR D 2 262 ? 404.088 387.618 187.155 1.00 105.90 ? 262 TYR D CE2   1 
ATOM   12064 C  CZ    . TYR D 2 262 ? 405.052 387.811 186.191 1.00 103.61 ? 262 TYR D CZ    1 
ATOM   12065 O  OH    . TYR D 2 262 ? 404.937 388.858 185.308 1.00 100.30 ? 262 TYR D OH    1 
ATOM   12066 N  N     . PRO D 2 263 ? 406.284 381.558 189.685 1.00 104.50 ? 263 PRO D N     1 
ATOM   12067 C  CA    . PRO D 2 263 ? 406.350 380.335 190.514 1.00 107.14 ? 263 PRO D CA    1 
ATOM   12068 C  C     . PRO D 2 263 ? 405.797 380.485 191.921 1.00 109.75 ? 263 PRO D C     1 
ATOM   12069 O  O     . PRO D 2 263 ? 405.206 379.535 192.448 1.00 112.23 ? 263 PRO D O     1 
ATOM   12070 C  CB    . PRO D 2 263 ? 407.853 380.013 190.544 1.00 102.06 ? 263 PRO D CB    1 
ATOM   12071 C  CG    . PRO D 2 263 ? 408.447 380.780 189.433 1.00 107.69 ? 263 PRO D CG    1 
ATOM   12072 C  CD    . PRO D 2 263 ? 407.639 382.021 189.332 1.00 103.93 ? 263 PRO D CD    1 
ATOM   12073 N  N     . ARG D 2 264 ? 405.958 381.654 192.538 1.00 104.12 ? 264 ARG D N     1 
ATOM   12074 C  CA    . ARG D 2 264 ? 405.513 381.866 193.909 1.00 102.50 ? 264 ARG D CA    1 
ATOM   12075 C  C     . ARG D 2 264 ? 404.063 382.320 194.007 1.00 104.78 ? 264 ARG D C     1 
ATOM   12076 O  O     . ARG D 2 264 ? 403.431 382.092 195.045 1.00 109.15 ? 264 ARG D O     1 
ATOM   12077 C  CB    . ARG D 2 264 ? 406.420 382.892 194.592 1.00 102.96 ? 264 ARG D CB    1 
ATOM   12078 C  CG    . ARG D 2 264 ? 407.832 382.367 194.836 1.00 105.20 ? 264 ARG D CG    1 
ATOM   12079 C  CD    . ARG D 2 264 ? 408.795 383.447 195.301 1.00 108.78 ? 264 ARG D CD    1 
ATOM   12080 N  NE    . ARG D 2 264 ? 408.748 383.612 196.755 1.00 105.72 ? 264 ARG D NE    1 
ATOM   12081 C  CZ    . ARG D 2 264 ? 408.540 384.740 197.431 1.00 110.47 ? 264 ARG D CZ    1 
ATOM   12082 N  NH1   . ARG D 2 264 ? 408.362 385.909 196.830 1.00 114.94 ? 264 ARG D NH1   1 
ATOM   12083 N  NH2   . ARG D 2 264 ? 408.516 384.696 198.759 1.00 113.10 ? 264 ARG D NH2   1 
ATOM   12084 N  N     . ILE D 2 265 ? 403.526 382.943 192.962 1.00 101.50 ? 265 ILE D N     1 
ATOM   12085 C  CA    . ILE D 2 265 ? 402.130 383.424 192.969 1.00 102.19 ? 265 ILE D CA    1 
ATOM   12086 C  C     . ILE D 2 265 ? 401.290 382.279 192.415 1.00 105.07 ? 265 ILE D C     1 
ATOM   12087 O  O     . ILE D 2 265 ? 400.991 382.196 191.222 1.00 111.88 ? 265 ILE D O     1 
ATOM   12088 C  CB    . ILE D 2 265 ? 401.964 384.720 192.166 1.00 100.13 ? 265 ILE D CB    1 
ATOM   12089 C  CG1   . ILE D 2 265 ? 402.717 385.880 192.828 1.00 97.44  ? 265 ILE D CG1   1 
ATOM   12090 C  CG2   . ILE D 2 265 ? 400.487 385.075 192.008 1.00 105.05 ? 265 ILE D CG2   1 
ATOM   12091 C  CD1   . ILE D 2 265 ? 403.276 386.860 191.831 1.00 102.13 ? 265 ILE D CD1   1 
ATOM   12092 N  N     . HIS D 2 266 ? 400.919 381.357 193.303 1.00 102.76 ? 266 HIS D N     1 
ATOM   12093 C  CA    . HIS D 2 266 ? 400.116 380.186 192.942 1.00 108.25 ? 266 HIS D CA    1 
ATOM   12094 C  C     . HIS D 2 266 ? 399.043 379.924 193.998 1.00 109.73 ? 266 HIS D C     1 
ATOM   12095 O  O     . HIS D 2 266 ? 398.883 378.804 194.486 1.00 113.79 ? 266 HIS D O     1 
ATOM   12096 C  CB    . HIS D 2 266 ? 401.017 378.969 192.696 1.00 111.14 ? 266 HIS D CB    1 
ATOM   12097 C  CG    . HIS D 2 266 ? 401.987 378.662 193.800 1.00 111.35 ? 266 HIS D CG    1 
ATOM   12098 N  ND1   . HIS D 2 266 ? 403.228 378.117 193.554 1.00 112.94 ? 266 HIS D ND1   1 
ATOM   12099 C  CD2   . HIS D 2 266 ? 401.890 378.777 195.145 1.00 107.23 ? 266 HIS D CD2   1 
ATOM   12100 C  CE1   . HIS D 2 266 ? 403.864 377.936 194.698 1.00 107.74 ? 266 HIS D CE1   1 
ATOM   12101 N  NE2   . HIS D 2 266 ? 403.073 378.329 195.679 1.00 105.59 ? 266 HIS D NE2   1 
ATOM   12102 N  N     . PHE D 2 267 ? 398.288 380.970 194.353 1.00 106.57 ? 267 PHE D N     1 
ATOM   12103 C  CA    . PHE D 2 267 ? 397.257 380.916 195.395 1.00 100.21 ? 267 PHE D CA    1 
ATOM   12104 C  C     . PHE D 2 267 ? 395.935 381.460 194.862 1.00 98.08  ? 267 PHE D C     1 
ATOM   12105 O  O     . PHE D 2 267 ? 395.591 382.621 195.121 1.00 99.68  ? 267 PHE D O     1 
ATOM   12106 C  CB    . PHE D 2 267 ? 397.684 381.721 196.622 1.00 96.38  ? 267 PHE D CB    1 
ATOM   12107 C  CG    . PHE D 2 267 ? 398.799 381.098 197.410 1.00 103.16 ? 267 PHE D CG    1 
ATOM   12108 C  CD1   . PHE D 2 267 ? 400.118 381.280 197.032 1.00 100.74 ? 267 PHE D CD1   1 
ATOM   12109 C  CD2   . PHE D 2 267 ? 398.533 380.362 198.548 1.00 103.54 ? 267 PHE D CD2   1 
ATOM   12110 C  CE1   . PHE D 2 267 ? 401.144 380.736 197.775 1.00 97.73  ? 267 PHE D CE1   1 
ATOM   12111 C  CE2   . PHE D 2 267 ? 399.558 379.805 199.286 1.00 102.78 ? 267 PHE D CE2   1 
ATOM   12112 C  CZ    . PHE D 2 267 ? 400.864 379.990 198.896 1.00 99.96  ? 267 PHE D CZ    1 
ATOM   12113 N  N     . PRO D 2 268 ? 395.160 380.660 194.128 1.00 92.01  ? 268 PRO D N     1 
ATOM   12114 C  CA    . PRO D 2 268 ? 393.836 381.116 193.689 1.00 98.96  ? 268 PRO D CA    1 
ATOM   12115 C  C     . PRO D 2 268 ? 392.806 381.043 194.814 1.00 94.84  ? 268 PRO D C     1 
ATOM   12116 O  O     . PRO D 2 268 ? 393.072 380.546 195.906 1.00 97.04  ? 268 PRO D O     1 
ATOM   12117 C  CB    . PRO D 2 268 ? 393.482 380.154 192.548 1.00 103.82 ? 268 PRO D CB    1 
ATOM   12118 C  CG    . PRO D 2 268 ? 394.739 379.446 192.217 1.00 98.67  ? 268 PRO D CG    1 
ATOM   12119 C  CD    . PRO D 2 268 ? 395.492 379.374 193.491 1.00 95.54  ? 268 PRO D CD    1 
ATOM   12120 N  N     . LEU D 2 269 ? 391.612 381.556 194.513 1.00 99.10  ? 269 LEU D N     1 
ATOM   12121 C  CA    . LEU D 2 269 ? 390.478 381.599 195.431 1.00 101.07 ? 269 LEU D CA    1 
ATOM   12122 C  C     . LEU D 2 269 ? 389.364 380.707 194.902 1.00 109.22 ? 269 LEU D C     1 
ATOM   12123 O  O     . LEU D 2 269 ? 388.944 380.853 193.750 1.00 110.57 ? 269 LEU D O     1 
ATOM   12124 C  CB    . LEU D 2 269 ? 389.948 383.025 195.591 1.00 105.58 ? 269 LEU D CB    1 
ATOM   12125 C  CG    . LEU D 2 269 ? 390.744 384.034 196.423 1.00 109.71 ? 269 LEU D CG    1 
ATOM   12126 C  CD1   . LEU D 2 269 ? 392.033 384.448 195.730 1.00 113.05 ? 269 LEU D CD1   1 
ATOM   12127 C  CD2   . LEU D 2 269 ? 389.878 385.255 196.707 1.00 110.50 ? 269 LEU D CD2   1 
ATOM   12128 N  N     . ALA D 2 270 ? 388.873 379.808 195.748 1.00 120.12 ? 270 ALA D N     1 
ATOM   12129 C  CA    . ALA D 2 270 ? 387.796 378.911 195.362 1.00 117.19 ? 270 ALA D CA    1 
ATOM   12130 C  C     . ALA D 2 270 ? 386.468 379.658 195.291 1.00 117.85 ? 270 ALA D C     1 
ATOM   12131 O  O     . ALA D 2 270 ? 386.256 380.659 195.980 1.00 122.75 ? 270 ALA D O     1 
ATOM   12132 C  CB    . ALA D 2 270 ? 387.689 377.754 196.353 1.00 121.89 ? 270 ALA D CB    1 
ATOM   12133 N  N     . THR D 2 271 ? 385.572 379.165 194.437 1.00 113.60 ? 271 THR D N     1 
ATOM   12134 C  CA    . THR D 2 271 ? 384.222 379.704 194.329 1.00 117.78 ? 271 THR D CA    1 
ATOM   12135 C  C     . THR D 2 271 ? 383.355 378.717 193.562 1.00 119.45 ? 271 THR D C     1 
ATOM   12136 O  O     . THR D 2 271 ? 383.791 378.159 192.552 1.00 126.97 ? 271 THR D O     1 
ATOM   12137 C  CB    . THR D 2 271 ? 384.204 381.071 193.627 1.00 117.94 ? 271 THR D CB    1 
ATOM   12138 O  OG1   . THR D 2 271 ? 384.925 382.033 194.406 1.00 120.58 ? 271 THR D OG1   1 
ATOM   12139 C  CG2   . THR D 2 271 ? 382.774 381.560 193.429 1.00 114.87 ? 271 THR D CG2   1 
ATOM   12140 N  N     . TYR D 2 272 ? 382.133 378.510 194.054 1.00 107.15 ? 272 TYR D N     1 
ATOM   12141 C  CA    . TYR D 2 272 ? 381.125 377.673 193.418 1.00 107.69 ? 272 TYR D CA    1 
ATOM   12142 C  C     . TYR D 2 272 ? 379.874 378.504 193.172 1.00 107.22 ? 272 TYR D C     1 
ATOM   12143 O  O     . TYR D 2 272 ? 379.565 379.427 193.932 1.00 102.02 ? 272 TYR D O     1 
ATOM   12144 C  CB    . TYR D 2 272 ? 380.784 376.445 194.293 1.00 104.04 ? 272 TYR D CB    1 
ATOM   12145 C  CG    . TYR D 2 272 ? 379.773 375.483 193.701 1.00 101.47 ? 272 TYR D CG    1 
ATOM   12146 C  CD1   . TYR D 2 272 ? 380.184 374.400 192.938 1.00 98.74  ? 272 TYR D CD1   1 
ATOM   12147 C  CD2   . TYR D 2 272 ? 378.412 375.633 193.938 1.00 110.15 ? 272 TYR D CD2   1 
ATOM   12148 C  CE1   . TYR D 2 272 ? 379.270 373.515 192.404 1.00 102.96 ? 272 TYR D CE1   1 
ATOM   12149 C  CE2   . TYR D 2 272 ? 377.493 374.755 193.407 1.00 109.83 ? 272 TYR D CE2   1 
ATOM   12150 C  CZ    . TYR D 2 272 ? 377.926 373.697 192.644 1.00 108.04 ? 272 TYR D CZ    1 
ATOM   12151 O  OH    . TYR D 2 272 ? 377.007 372.820 192.118 1.00 117.82 ? 272 TYR D OH    1 
ATOM   12152 N  N     . ALA D 2 273 ? 379.167 378.182 192.092 1.00 111.00 ? 273 ALA D N     1 
ATOM   12153 C  CA    . ALA D 2 273 ? 377.834 378.707 191.856 1.00 106.05 ? 273 ALA D CA    1 
ATOM   12154 C  C     . ALA D 2 273 ? 377.063 377.669 191.055 1.00 113.64 ? 273 ALA D C     1 
ATOM   12155 O  O     . ALA D 2 273 ? 377.682 376.853 190.363 1.00 116.90 ? 273 ALA D O     1 
ATOM   12156 C  CB    . ALA D 2 273 ? 377.875 380.046 191.106 1.00 104.92 ? 273 ALA D CB    1 
ATOM   12157 N  N     . PRO D 2 274 ? 375.720 377.653 191.130 1.00 122.91 ? 274 PRO D N     1 
ATOM   12158 C  CA    . PRO D 2 274 ? 374.817 378.474 191.950 1.00 120.63 ? 274 PRO D CA    1 
ATOM   12159 C  C     . PRO D 2 274 ? 374.619 377.903 193.341 1.00 119.38 ? 274 PRO D C     1 
ATOM   12160 O  O     . PRO D 2 274 ? 374.017 376.842 193.482 1.00 122.80 ? 274 PRO D O     1 
ATOM   12161 C  CB    . PRO D 2 274 ? 373.498 378.442 191.178 1.00 123.66 ? 274 PRO D CB    1 
ATOM   12162 C  CG    . PRO D 2 274 ? 373.566 377.274 190.250 1.00 129.18 ? 274 PRO D CG    1 
ATOM   12163 C  CD    . PRO D 2 274 ? 374.982 376.770 190.212 1.00 123.14 ? 274 PRO D CD    1 
ATOM   12164 N  N     . VAL D 2 275 ? 375.111 378.577 194.375 1.00 120.57 ? 275 VAL D N     1 
ATOM   12165 C  CA    . VAL D 2 275 ? 374.708 378.264 195.744 1.00 120.63 ? 275 VAL D CA    1 
ATOM   12166 C  C     . VAL D 2 275 ? 373.355 378.927 195.981 1.00 122.81 ? 275 VAL D C     1 
ATOM   12167 O  O     . VAL D 2 275 ? 373.231 380.155 195.933 1.00 129.08 ? 275 VAL D O     1 
ATOM   12168 C  CB    . VAL D 2 275 ? 375.761 378.704 196.782 1.00 122.23 ? 275 VAL D CB    1 
ATOM   12169 C  CG1   . VAL D 2 275 ? 376.950 377.755 196.758 1.00 122.57 ? 275 VAL D CG1   1 
ATOM   12170 C  CG2   . VAL D 2 275 ? 376.267 380.153 196.600 1.00 125.63 ? 275 VAL D CG2   1 
ATOM   12171 N  N     . ILE D 2 276 ? 372.324 378.112 196.185 1.00 129.29 ? 276 ILE D N     1 
ATOM   12172 C  CA    . ILE D 2 276 ? 370.959 378.621 196.258 1.00 134.24 ? 276 ILE D CA    1 
ATOM   12173 C  C     . ILE D 2 276 ? 370.110 377.598 196.995 1.00 135.68 ? 276 ILE D C     1 
ATOM   12174 O  O     . ILE D 2 276 ? 370.269 376.387 196.816 1.00 133.91 ? 276 ILE D O     1 
ATOM   12175 C  CB    . ILE D 2 276 ? 370.402 378.929 194.846 1.00 131.96 ? 276 ILE D CB    1 
ATOM   12176 C  CG1   . ILE D 2 276 ? 369.155 379.818 194.924 1.00 135.36 ? 276 ILE D CG1   1 
ATOM   12177 C  CG2   . ILE D 2 276 ? 370.085 377.643 194.083 1.00 129.99 ? 276 ILE D CG2   1 
ATOM   12178 C  CD1   . ILE D 2 276 ? 369.468 381.283 195.146 1.00 134.87 ? 276 ILE D CD1   1 
ATOM   12179 N  N     . SER D 2 277 ? 369.213 378.099 197.837 1.00 152.52 ? 277 SER D N     1 
ATOM   12180 C  CA    . SER D 2 277 ? 368.300 377.238 198.566 1.00 152.39 ? 277 SER D CA    1 
ATOM   12181 C  C     . SER D 2 277 ? 367.328 376.560 197.611 1.00 157.36 ? 277 SER D C     1 
ATOM   12182 O  O     . SER D 2 277 ? 367.034 377.066 196.525 1.00 160.54 ? 277 SER D O     1 
ATOM   12183 C  CB    . SER D 2 277 ? 367.517 378.046 199.597 1.00 151.75 ? 277 SER D CB    1 
ATOM   12184 O  OG    . SER D 2 277 ? 366.526 377.250 200.221 1.00 156.66 ? 277 SER D OG    1 
ATOM   12185 N  N     . ALA D 2 278 ? 366.823 375.399 198.030 1.00 163.98 ? 278 ALA D N     1 
ATOM   12186 C  CA    . ALA D 2 278 ? 365.780 374.733 197.259 1.00 160.73 ? 278 ALA D CA    1 
ATOM   12187 C  C     . ALA D 2 278 ? 364.500 375.559 197.216 1.00 160.85 ? 278 ALA D C     1 
ATOM   12188 O  O     . ALA D 2 278 ? 363.741 375.472 196.244 1.00 159.91 ? 278 ALA D O     1 
ATOM   12189 C  CB    . ALA D 2 278 ? 365.498 373.351 197.845 1.00 157.06 ? 278 ALA D CB    1 
ATOM   12190 N  N     . GLU D 2 279 ? 364.242 376.367 198.249 1.00 174.54 ? 279 GLU D N     1 
ATOM   12191 C  CA    . GLU D 2 279 ? 363.017 377.161 198.274 1.00 172.19 ? 279 GLU D CA    1 
ATOM   12192 C  C     . GLU D 2 279 ? 363.068 378.276 197.237 1.00 171.62 ? 279 GLU D C     1 
ATOM   12193 O  O     . GLU D 2 279 ? 362.085 378.512 196.525 1.00 171.73 ? 279 GLU D O     1 
ATOM   12194 C  CB    . GLU D 2 279 ? 362.738 377.754 199.670 1.00 174.44 ? 279 GLU D CB    1 
ATOM   12195 C  CG    . GLU D 2 279 ? 362.378 376.826 200.893 1.00 176.17 ? 279 GLU D CG    1 
ATOM   12196 C  CD    . GLU D 2 279 ? 362.188 377.494 202.247 1.00 175.77 ? 279 GLU D CD    1 
ATOM   12197 O  OE1   . GLU D 2 279 ? 362.505 378.694 202.371 1.00 178.29 ? 279 GLU D OE1   1 
ATOM   12198 O  OE2   . GLU D 2 279 ? 361.712 376.816 203.185 1.00 175.79 ? 279 GLU D OE2   1 
ATOM   12199 N  N     . LYS D 2 280 ? 364.207 378.965 197.131 1.00 166.33 ? 280 LYS D N     1 
ATOM   12200 C  CA    . LYS D 2 280 ? 364.378 380.042 196.161 1.00 167.17 ? 280 LYS D CA    1 
ATOM   12201 C  C     . LYS D 2 280 ? 364.849 379.557 194.794 1.00 167.90 ? 280 LYS D C     1 
ATOM   12202 O  O     . LYS D 2 280 ? 364.901 380.366 193.862 1.00 168.50 ? 280 LYS D O     1 
ATOM   12203 C  CB    . LYS D 2 280 ? 365.374 381.080 196.693 1.00 164.45 ? 280 LYS D CB    1 
ATOM   12204 C  CG    . LYS D 2 280 ? 364.953 382.543 196.518 1.00 163.98 ? 280 LYS D CG    1 
ATOM   12205 C  CD    . LYS D 2 280 ? 363.779 382.954 197.410 1.00 165.59 ? 280 LYS D CD    1 
ATOM   12206 C  CE    . LYS D 2 280 ? 363.254 384.331 197.027 1.00 164.34 ? 280 LYS D CE    1 
ATOM   12207 N  NZ    . LYS D 2 280 ? 362.282 384.864 198.022 1.00 161.08 ? 280 LYS D NZ    1 
ATOM   12208 N  N     . ALA D 2 281 ? 365.196 378.274 194.643 1.00 168.03 ? 281 ALA D N     1 
ATOM   12209 C  CA    . ALA D 2 281 ? 365.634 377.779 193.341 1.00 165.64 ? 281 ALA D CA    1 
ATOM   12210 C  C     . ALA D 2 281 ? 364.513 377.817 192.310 1.00 166.86 ? 281 ALA D C     1 
ATOM   12211 O  O     . ALA D 2 281 ? 364.785 377.937 191.110 1.00 167.14 ? 281 ALA D O     1 
ATOM   12212 C  CB    . ALA D 2 281 ? 366.173 376.355 193.475 1.00 164.77 ? 281 ALA D CB    1 
ATOM   12213 N  N     . TYR D 2 282 ? 363.257 377.703 192.750 1.00 166.19 ? 282 TYR D N     1 
ATOM   12214 C  CA    . TYR D 2 282 ? 362.137 377.693 191.814 1.00 164.15 ? 282 TYR D CA    1 
ATOM   12215 C  C     . TYR D 2 282 ? 361.999 379.026 191.090 1.00 166.75 ? 282 TYR D C     1 
ATOM   12216 O  O     . TYR D 2 282 ? 361.715 379.059 189.887 1.00 169.89 ? 282 TYR D O     1 
ATOM   12217 C  CB    . TYR D 2 282 ? 360.843 377.358 192.554 1.00 161.57 ? 282 TYR D CB    1 
ATOM   12218 C  CG    . TYR D 2 282 ? 360.806 375.959 193.125 1.00 162.89 ? 282 TYR D CG    1 
ATOM   12219 C  CD1   . TYR D 2 282 ? 360.387 374.885 192.353 1.00 164.29 ? 282 TYR D CD1   1 
ATOM   12220 C  CD2   . TYR D 2 282 ? 361.183 375.714 194.438 1.00 163.21 ? 282 TYR D CD2   1 
ATOM   12221 C  CE1   . TYR D 2 282 ? 360.349 373.605 192.871 1.00 164.87 ? 282 TYR D CE1   1 
ATOM   12222 C  CE2   . TYR D 2 282 ? 361.148 374.438 194.965 1.00 163.40 ? 282 TYR D CE2   1 
ATOM   12223 C  CZ    . TYR D 2 282 ? 360.731 373.387 194.178 1.00 163.97 ? 282 TYR D CZ    1 
ATOM   12224 O  OH    . TYR D 2 282 ? 360.695 372.115 194.699 1.00 164.23 ? 282 TYR D OH    1 
ATOM   12225 N  N     . HIS D 2 283 ? 362.196 380.136 191.801 1.00 172.59 ? 283 HIS D N     1 
ATOM   12226 C  CA    . HIS D 2 283 ? 361.933 381.453 191.234 1.00 170.99 ? 283 HIS D CA    1 
ATOM   12227 C  C     . HIS D 2 283 ? 362.985 381.899 190.226 1.00 172.03 ? 283 HIS D C     1 
ATOM   12228 O  O     . HIS D 2 283 ? 362.661 382.693 189.336 1.00 173.27 ? 283 HIS D O     1 
ATOM   12229 C  CB    . HIS D 2 283 ? 361.836 382.490 192.354 1.00 170.73 ? 283 HIS D CB    1 
ATOM   12230 C  CG    . HIS D 2 283 ? 360.702 382.248 193.301 1.00 172.26 ? 283 HIS D CG    1 
ATOM   12231 N  ND1   . HIS D 2 283 ? 360.769 381.323 194.321 1.00 172.24 ? 283 HIS D ND1   1 
ATOM   12232 C  CD2   . HIS D 2 283 ? 359.473 382.809 193.381 1.00 172.56 ? 283 HIS D CD2   1 
ATOM   12233 C  CE1   . HIS D 2 283 ? 359.629 381.326 194.989 1.00 170.33 ? 283 HIS D CE1   1 
ATOM   12234 N  NE2   . HIS D 2 283 ? 358.826 382.218 194.439 1.00 170.67 ? 283 HIS D NE2   1 
ATOM   12235 N  N     . GLU D 2 284 ? 364.218 381.408 190.335 1.00 170.33 ? 284 GLU D N     1 
ATOM   12236 C  CA    . GLU D 2 284 ? 365.334 381.861 189.512 1.00 168.04 ? 284 GLU D CA    1 
ATOM   12237 C  C     . GLU D 2 284 ? 365.614 380.860 188.397 1.00 167.78 ? 284 GLU D C     1 
ATOM   12238 O  O     . GLU D 2 284 ? 365.460 379.649 188.580 1.00 170.26 ? 284 GLU D O     1 
ATOM   12239 C  CB    . GLU D 2 284 ? 366.584 382.056 190.370 1.00 167.05 ? 284 GLU D CB    1 
ATOM   12240 C  CG    . GLU D 2 284 ? 366.460 383.154 191.414 1.00 172.15 ? 284 GLU D CG    1 
ATOM   12241 C  CD    . GLU D 2 284 ? 367.687 383.261 192.299 1.00 170.90 ? 284 GLU D CD    1 
ATOM   12242 O  OE1   . GLU D 2 284 ? 368.568 382.379 192.212 1.00 168.28 ? 284 GLU D OE1   1 
ATOM   12243 O  OE2   . GLU D 2 284 ? 367.771 384.227 193.086 1.00 170.41 ? 284 GLU D OE2   1 
ATOM   12244 N  N     . GLN D 2 285 ? 366.029 381.379 187.238 1.00 156.51 ? 285 GLN D N     1 
ATOM   12245 C  CA    . GLN D 2 285 ? 366.264 380.523 186.077 1.00 157.28 ? 285 GLN D CA    1 
ATOM   12246 C  C     . GLN D 2 285 ? 367.566 379.741 186.210 1.00 155.09 ? 285 GLN D C     1 
ATOM   12247 O  O     . GLN D 2 285 ? 367.635 378.573 185.811 1.00 154.35 ? 285 GLN D O     1 
ATOM   12248 C  CB    . GLN D 2 285 ? 366.277 381.372 184.804 1.00 155.19 ? 285 GLN D CB    1 
ATOM   12249 C  CG    . GLN D 2 285 ? 366.359 380.570 183.509 1.00 154.57 ? 285 GLN D CG    1 
ATOM   12250 C  CD    . GLN D 2 285 ? 366.196 381.434 182.272 1.00 158.25 ? 285 GLN D CD    1 
ATOM   12251 O  OE1   . GLN D 2 285 ? 365.541 382.475 182.307 1.00 159.64 ? 285 GLN D OE1   1 
ATOM   12252 N  NE2   . GLN D 2 285 ? 366.795 381.002 181.168 1.00 158.50 ? 285 GLN D NE2   1 
ATOM   12253 N  N     . LEU D 2 286 ? 368.610 380.376 186.752 1.00 138.58 ? 286 LEU D N     1 
ATOM   12254 C  CA    . LEU D 2 286 ? 369.946 379.784 186.893 1.00 136.26 ? 286 LEU D CA    1 
ATOM   12255 C  C     . LEU D 2 286 ? 370.511 379.390 185.525 1.00 138.31 ? 286 LEU D C     1 
ATOM   12256 O  O     . LEU D 2 286 ? 370.897 378.243 185.295 1.00 142.01 ? 286 LEU D O     1 
ATOM   12257 C  CB    . LEU D 2 286 ? 369.953 378.580 187.851 1.00 139.57 ? 286 LEU D CB    1 
ATOM   12258 C  CG    . LEU D 2 286 ? 369.761 378.774 189.362 1.00 138.32 ? 286 LEU D CG    1 
ATOM   12259 C  CD1   . LEU D 2 286 ? 370.724 379.803 189.936 1.00 135.87 ? 286 LEU D CD1   1 
ATOM   12260 C  CD2   . LEU D 2 286 ? 368.329 379.120 189.699 1.00 140.55 ? 286 LEU D CD2   1 
ATOM   12261 N  N     . SER D 2 287 ? 370.545 380.357 184.611 1.00 123.27 ? 287 SER D N     1 
ATOM   12262 C  CA    . SER D 2 287 ? 371.154 380.143 183.308 1.00 124.33 ? 287 SER D CA    1 
ATOM   12263 C  C     . SER D 2 287 ? 372.664 380.365 183.394 1.00 121.14 ? 287 SER D C     1 
ATOM   12264 O  O     . SER D 2 287 ? 373.220 380.689 184.452 1.00 125.00 ? 287 SER D O     1 
ATOM   12265 C  CB    . SER D 2 287 ? 370.522 381.062 182.268 1.00 124.07 ? 287 SER D CB    1 
ATOM   12266 O  OG    . SER D 2 287 ? 371.018 380.777 180.973 1.00 124.24 ? 287 SER D OG    1 
ATOM   12267 N  N     . VAL D 2 288 ? 373.328 380.184 182.249 1.00 107.65 ? 288 VAL D N     1 
ATOM   12268 C  CA    . VAL D 2 288 ? 374.785 380.274 182.194 1.00 108.41 ? 288 VAL D CA    1 
ATOM   12269 C  C     . VAL D 2 288 ? 375.245 381.684 182.542 1.00 112.89 ? 288 VAL D C     1 
ATOM   12270 O  O     . VAL D 2 288 ? 376.194 381.869 183.312 1.00 119.45 ? 288 VAL D O     1 
ATOM   12271 C  CB    . VAL D 2 288 ? 375.293 379.834 180.807 1.00 108.34 ? 288 VAL D CB    1 
ATOM   12272 C  CG1   . VAL D 2 288 ? 376.784 380.130 180.652 1.00 106.88 ? 288 VAL D CG1   1 
ATOM   12273 C  CG2   . VAL D 2 288 ? 375.015 378.347 180.584 1.00 111.13 ? 288 VAL D CG2   1 
ATOM   12274 N  N     . ALA D 2 289 ? 374.575 382.697 181.988 1.00 105.70 ? 289 ALA D N     1 
ATOM   12275 C  CA    . ALA D 2 289 ? 374.935 384.078 182.292 1.00 101.45 ? 289 ALA D CA    1 
ATOM   12276 C  C     . ALA D 2 289 ? 374.706 384.397 183.764 1.00 105.52 ? 289 ALA D C     1 
ATOM   12277 O  O     . ALA D 2 289 ? 375.520 385.085 184.391 1.00 112.08 ? 289 ALA D O     1 
ATOM   12278 C  CB    . ALA D 2 289 ? 374.136 385.032 181.406 1.00 100.79 ? 289 ALA D CB    1 
ATOM   12279 N  N     . GLU D 2 290 ? 373.610 383.891 184.334 1.00 124.18 ? 290 GLU D N     1 
ATOM   12280 C  CA    . GLU D 2 290 ? 373.307 384.149 185.739 1.00 122.60 ? 290 GLU D CA    1 
ATOM   12281 C  C     . GLU D 2 290 ? 374.368 383.553 186.655 1.00 120.17 ? 290 GLU D C     1 
ATOM   12282 O  O     . GLU D 2 290 ? 374.881 384.237 187.549 1.00 122.36 ? 290 GLU D O     1 
ATOM   12283 C  CB    . GLU D 2 290 ? 371.922 383.597 186.090 1.00 125.94 ? 290 GLU D CB    1 
ATOM   12284 C  CG    . GLU D 2 290 ? 370.735 384.299 185.416 1.00 127.55 ? 290 GLU D CG    1 
ATOM   12285 C  CD    . GLU D 2 290 ? 369.384 383.677 185.733 1.00 132.42 ? 290 GLU D CD    1 
ATOM   12286 O  OE1   . GLU D 2 290 ? 369.348 382.580 186.326 1.00 133.66 ? 290 GLU D OE1   1 
ATOM   12287 O  OE2   . GLU D 2 290 ? 368.354 384.293 185.389 1.00 132.02 ? 290 GLU D OE2   1 
ATOM   12288 N  N     . ILE D 2 291 ? 374.721 382.281 186.447 1.00 117.66 ? 291 ILE D N     1 
ATOM   12289 C  CA    . ILE D 2 291 ? 375.723 381.661 187.314 1.00 116.12 ? 291 ILE D CA    1 
ATOM   12290 C  C     . ILE D 2 291 ? 377.095 382.288 187.083 1.00 118.95 ? 291 ILE D C     1 
ATOM   12291 O  O     . ILE D 2 291 ? 377.884 382.449 188.023 1.00 122.61 ? 291 ILE D O     1 
ATOM   12292 C  CB    . ILE D 2 291 ? 375.750 380.129 187.128 1.00 117.44 ? 291 ILE D CB    1 
ATOM   12293 C  CG1   . ILE D 2 291 ? 376.186 379.723 185.710 1.00 126.00 ? 291 ILE D CG1   1 
ATOM   12294 C  CG2   . ILE D 2 291 ? 374.382 379.542 187.460 1.00 122.11 ? 291 ILE D CG2   1 
ATOM   12295 C  CD1   . ILE D 2 291 ? 376.077 378.237 185.419 1.00 126.46 ? 291 ILE D CD1   1 
ATOM   12296 N  N     . THR D 2 292 ? 377.403 382.657 185.835 1.00 110.82 ? 292 THR D N     1 
ATOM   12297 C  CA    . THR D 2 292 ? 378.690 383.280 185.549 1.00 105.72 ? 292 THR D CA    1 
ATOM   12298 C  C     . THR D 2 292 ? 378.813 384.634 186.236 1.00 107.50 ? 292 THR D C     1 
ATOM   12299 O  O     . THR D 2 292 ? 379.879 384.978 186.757 1.00 110.75 ? 292 THR D O     1 
ATOM   12300 C  CB    . THR D 2 292 ? 378.870 383.420 184.038 1.00 109.52 ? 292 THR D CB    1 
ATOM   12301 O  OG1   . THR D 2 292 ? 378.756 382.133 183.418 1.00 113.92 ? 292 THR D OG1   1 
ATOM   12302 C  CG2   . THR D 2 292 ? 380.226 384.009 183.712 1.00 111.88 ? 292 THR D CG2   1 
ATOM   12303 N  N     . ASN D 2 293 ? 377.733 385.418 186.247 1.00 117.52 ? 293 ASN D N     1 
ATOM   12304 C  CA    . ASN D 2 293 ? 377.748 386.673 186.990 1.00 115.70 ? 293 ASN D CA    1 
ATOM   12305 C  C     . ASN D 2 293 ? 377.823 386.423 188.490 1.00 115.89 ? 293 ASN D C     1 
ATOM   12306 O  O     . ASN D 2 293 ? 378.492 387.168 189.215 1.00 116.40 ? 293 ASN D O     1 
ATOM   12307 C  CB    . ASN D 2 293 ? 376.513 387.504 186.649 1.00 114.36 ? 293 ASN D CB    1 
ATOM   12308 C  CG    . ASN D 2 293 ? 376.691 388.315 185.384 1.00 114.02 ? 293 ASN D CG    1 
ATOM   12309 O  OD1   . ASN D 2 293 ? 377.263 389.403 185.407 1.00 112.66 ? 293 ASN D OD1   1 
ATOM   12310 N  ND2   . ASN D 2 293 ? 376.202 387.787 184.268 1.00 122.08 ? 293 ASN D ND2   1 
ATOM   12311 N  N     . ALA D 2 294 ? 377.137 385.384 188.974 1.00 121.75 ? 294 ALA D N     1 
ATOM   12312 C  CA    . ALA D 2 294 ? 377.176 385.065 190.398 1.00 118.38 ? 294 ALA D CA    1 
ATOM   12313 C  C     . ALA D 2 294 ? 378.572 384.661 190.851 1.00 118.72 ? 294 ALA D C     1 
ATOM   12314 O  O     . ALA D 2 294 ? 378.916 384.846 192.023 1.00 121.26 ? 294 ALA D O     1 
ATOM   12315 C  CB    . ALA D 2 294 ? 376.180 383.949 190.710 1.00 122.12 ? 294 ALA D CB    1 
ATOM   12316 N  N     . CYS D 2 295 ? 379.376 384.089 189.952 1.00 127.26 ? 295 CYS D N     1 
ATOM   12317 C  CA    . CYS D 2 295 ? 380.738 383.707 190.317 1.00 124.48 ? 295 CYS D CA    1 
ATOM   12318 C  C     . CYS D 2 295 ? 381.576 384.916 190.718 1.00 124.23 ? 295 CYS D C     1 
ATOM   12319 O  O     . CYS D 2 295 ? 382.353 384.849 191.677 1.00 130.91 ? 295 CYS D O     1 
ATOM   12320 C  CB    . CYS D 2 295 ? 381.410 382.972 189.158 1.00 125.35 ? 295 CYS D CB    1 
ATOM   12321 S  SG    . CYS D 2 295 ? 381.019 381.219 189.063 1.00 147.95 ? 295 CYS D SG    1 
ATOM   12322 N  N     . PHE D 2 296 ? 381.429 386.028 190.003 1.00 104.90 ? 296 PHE D N     1 
ATOM   12323 C  CA    . PHE D 2 296 ? 382.347 387.156 190.111 1.00 100.00 ? 296 PHE D CA    1 
ATOM   12324 C  C     . PHE D 2 296 ? 381.939 388.203 191.144 1.00 104.03 ? 296 PHE D C     1 
ATOM   12325 O  O     . PHE D 2 296 ? 382.675 389.178 191.324 1.00 101.59 ? 296 PHE D O     1 
ATOM   12326 C  CB    . PHE D 2 296 ? 382.501 387.823 188.741 1.00 99.73  ? 296 PHE D CB    1 
ATOM   12327 C  CG    . PHE D 2 296 ? 383.436 387.097 187.826 1.00 102.49 ? 296 PHE D CG    1 
ATOM   12328 C  CD1   . PHE D 2 296 ? 383.012 385.991 187.112 1.00 108.09 ? 296 PHE D CD1   1 
ATOM   12329 C  CD2   . PHE D 2 296 ? 384.743 387.521 187.682 1.00 101.08 ? 296 PHE D CD2   1 
ATOM   12330 C  CE1   . PHE D 2 296 ? 383.878 385.322 186.271 1.00 107.40 ? 296 PHE D CE1   1 
ATOM   12331 C  CE2   . PHE D 2 296 ? 385.609 386.860 186.844 1.00 103.99 ? 296 PHE D CE2   1 
ATOM   12332 C  CZ    . PHE D 2 296 ? 385.178 385.759 186.137 1.00 106.82 ? 296 PHE D CZ    1 
ATOM   12333 N  N     . GLU D 2 297 ? 380.809 388.040 191.826 1.00 128.33 ? 297 GLU D N     1 
ATOM   12334 C  CA    . GLU D 2 297 ? 380.445 389.006 192.852 1.00 126.74 ? 297 GLU D CA    1 
ATOM   12335 C  C     . GLU D 2 297 ? 381.410 388.887 194.035 1.00 128.81 ? 297 GLU D C     1 
ATOM   12336 O  O     . GLU D 2 297 ? 381.919 387.795 194.304 1.00 133.04 ? 297 GLU D O     1 
ATOM   12337 C  CB    . GLU D 2 297 ? 379.010 388.776 193.337 1.00 128.35 ? 297 GLU D CB    1 
ATOM   12338 C  CG    . GLU D 2 297 ? 377.920 388.641 192.260 1.00 131.67 ? 297 GLU D CG    1 
ATOM   12339 C  CD    . GLU D 2 297 ? 377.934 389.720 191.180 1.00 135.98 ? 297 GLU D CD    1 
ATOM   12340 O  OE1   . GLU D 2 297 ? 378.513 390.806 191.387 1.00 134.36 ? 297 GLU D OE1   1 
ATOM   12341 O  OE2   . GLU D 2 297 ? 377.344 389.477 190.107 1.00 138.18 ? 297 GLU D OE2   1 
ATOM   12342 N  N     . PRO D 2 298 ? 381.692 389.980 194.761 1.00 126.10 ? 298 PRO D N     1 
ATOM   12343 C  CA    . PRO D 2 298 ? 382.488 389.818 195.991 1.00 124.15 ? 298 PRO D CA    1 
ATOM   12344 C  C     . PRO D 2 298 ? 381.779 389.006 197.058 1.00 125.65 ? 298 PRO D C     1 
ATOM   12345 O  O     . PRO D 2 298 ? 382.441 388.389 197.902 1.00 124.18 ? 298 PRO D O     1 
ATOM   12346 C  CB    . PRO D 2 298 ? 382.727 391.263 196.458 1.00 124.77 ? 298 PRO D CB    1 
ATOM   12347 C  CG    . PRO D 2 298 ? 382.356 392.125 195.315 1.00 126.47 ? 298 PRO D CG    1 
ATOM   12348 C  CD    . PRO D 2 298 ? 381.295 391.389 194.585 1.00 127.61 ? 298 PRO D CD    1 
ATOM   12349 N  N     . ALA D 2 299 ? 380.444 388.999 197.047 1.00 124.09 ? 299 ALA D N     1 
ATOM   12350 C  CA    . ALA D 2 299 ? 379.679 388.345 198.102 1.00 121.36 ? 299 ALA D CA    1 
ATOM   12351 C  C     . ALA D 2 299 ? 379.892 386.836 198.125 1.00 121.50 ? 299 ALA D C     1 
ATOM   12352 O  O     . ALA D 2 299 ? 379.950 386.242 199.208 1.00 117.70 ? 299 ALA D O     1 
ATOM   12353 C  CB    . ALA D 2 299 ? 378.195 388.665 197.928 1.00 119.33 ? 299 ALA D CB    1 
ATOM   12354 N  N     . ASN D 2 300 ? 380.018 386.207 196.959 1.00 122.10 ? 300 ASN D N     1 
ATOM   12355 C  CA    . ASN D 2 300 ? 380.065 384.754 196.845 1.00 122.10 ? 300 ASN D CA    1 
ATOM   12356 C  C     . ASN D 2 300 ? 381.478 384.185 196.789 1.00 120.40 ? 300 ASN D C     1 
ATOM   12357 O  O     . ASN D 2 300 ? 381.634 382.999 196.482 1.00 119.59 ? 300 ASN D O     1 
ATOM   12358 C  CB    . ASN D 2 300 ? 379.279 384.307 195.609 1.00 122.23 ? 300 ASN D CB    1 
ATOM   12359 C  CG    . ASN D 2 300 ? 378.012 385.116 195.406 1.00 126.50 ? 300 ASN D CG    1 
ATOM   12360 O  OD1   . ASN D 2 300 ? 377.242 385.324 196.343 1.00 128.01 ? 300 ASN D OD1   1 
ATOM   12361 N  ND2   . ASN D 2 300 ? 377.788 385.576 194.184 1.00 126.41 ? 300 ASN D ND2   1 
ATOM   12362 N  N     . GLN D 2 301 ? 382.506 384.984 197.072 1.00 117.34 ? 301 GLN D N     1 
ATOM   12363 C  CA    . GLN D 2 301 ? 383.855 384.447 197.183 1.00 119.72 ? 301 GLN D CA    1 
ATOM   12364 C  C     . GLN D 2 301 ? 384.013 383.686 198.492 1.00 121.00 ? 301 GLN D C     1 
ATOM   12365 O  O     . GLN D 2 301 ? 383.517 384.112 199.539 1.00 125.51 ? 301 GLN D O     1 
ATOM   12366 C  CB    . GLN D 2 301 ? 384.889 385.572 197.109 1.00 118.97 ? 301 GLN D CB    1 
ATOM   12367 C  CG    . GLN D 2 301 ? 384.743 386.514 195.919 1.00 120.51 ? 301 GLN D CG    1 
ATOM   12368 C  CD    . GLN D 2 301 ? 384.794 385.789 194.589 1.00 130.16 ? 301 GLN D CD    1 
ATOM   12369 O  OE1   . GLN D 2 301 ? 385.741 385.056 194.309 1.00 130.37 ? 301 GLN D OE1   1 
ATOM   12370 N  NE2   . GLN D 2 301 ? 383.775 385.989 193.762 1.00 135.52 ? 301 GLN D NE2   1 
ATOM   12371 N  N     . MET D 2 302 ? 384.721 382.559 198.431 1.00 121.47 ? 302 MET D N     1 
ATOM   12372 C  CA    . MET D 2 302 ? 384.969 381.714 199.592 1.00 123.70 ? 302 MET D CA    1 
ATOM   12373 C  C     . MET D 2 302 ? 386.229 382.106 200.365 1.00 123.90 ? 302 MET D C     1 
ATOM   12374 O  O     . MET D 2 302 ? 386.634 381.369 201.270 1.00 125.84 ? 302 MET D O     1 
ATOM   12375 C  CB    . MET D 2 302 ? 385.049 380.243 199.162 1.00 123.85 ? 302 MET D CB    1 
ATOM   12376 C  CG    . MET D 2 302 ? 383.711 379.664 198.718 1.00 127.23 ? 302 MET D CG    1 
ATOM   12377 S  SD    . MET D 2 302 ? 383.486 377.945 199.194 1.00 138.89 ? 302 MET D SD    1 
ATOM   12378 C  CE    . MET D 2 302 ? 383.265 377.190 197.596 1.00 123.64 ? 302 MET D CE    1 
ATOM   12379 N  N     . VAL D 2 303 ? 386.860 383.231 200.026 1.00 110.88 ? 303 VAL D N     1 
ATOM   12380 C  CA    . VAL D 2 303 ? 387.888 383.859 200.848 1.00 109.45 ? 303 VAL D CA    1 
ATOM   12381 C  C     . VAL D 2 303 ? 387.461 385.299 201.083 1.00 114.72 ? 303 VAL D C     1 
ATOM   12382 O  O     . VAL D 2 303 ? 387.104 386.006 200.134 1.00 118.06 ? 303 VAL D O     1 
ATOM   12383 C  CB    . VAL D 2 303 ? 389.275 383.798 200.184 1.00 103.21 ? 303 VAL D CB    1 
ATOM   12384 C  CG1   . VAL D 2 303 ? 390.371 384.122 201.199 1.00 104.63 ? 303 VAL D CG1   1 
ATOM   12385 C  CG2   . VAL D 2 303 ? 389.503 382.435 199.552 1.00 107.28 ? 303 VAL D CG2   1 
ATOM   12386 N  N     . LYS D 2 304 ? 387.503 385.735 202.342 1.00 124.85 ? 304 LYS D N     1 
ATOM   12387 C  CA    . LYS D 2 304 ? 387.040 387.074 202.710 1.00 121.97 ? 304 LYS D CA    1 
ATOM   12388 C  C     . LYS D 2 304 ? 388.068 388.093 202.224 1.00 125.35 ? 304 LYS D C     1 
ATOM   12389 O  O     . LYS D 2 304 ? 388.890 388.617 202.979 1.00 129.42 ? 304 LYS D O     1 
ATOM   12390 C  CB    . LYS D 2 304 ? 386.822 387.179 204.216 1.00 124.08 ? 304 LYS D CB    1 
ATOM   12391 C  CG    . LYS D 2 304 ? 385.451 386.722 204.707 1.00 128.84 ? 304 LYS D CG    1 
ATOM   12392 C  CD    . LYS D 2 304 ? 384.657 387.877 205.300 1.00 124.91 ? 304 LYS D CD    1 
ATOM   12393 C  CE    . LYS D 2 304 ? 383.215 387.487 205.556 1.00 129.63 ? 304 LYS D CE    1 
ATOM   12394 N  NZ    . LYS D 2 304 ? 382.509 388.511 206.372 1.00 129.75 ? 304 LYS D NZ    1 
ATOM   12395 N  N     . CYS D 2 305 ? 388.018 388.364 200.922 1.00 121.89 ? 305 CYS D N     1 
ATOM   12396 C  CA    . CYS D 2 305 ? 388.909 389.320 200.274 1.00 120.49 ? 305 CYS D CA    1 
ATOM   12397 C  C     . CYS D 2 305 ? 388.138 389.939 199.122 1.00 118.79 ? 305 CYS D C     1 
ATOM   12398 O  O     . CYS D 2 305 ? 387.751 389.227 198.192 1.00 121.81 ? 305 CYS D O     1 
ATOM   12399 C  CB    . CYS D 2 305 ? 390.183 388.645 199.758 1.00 122.08 ? 305 CYS D CB    1 
ATOM   12400 S  SG    . CYS D 2 305 ? 391.207 387.848 201.010 1.00 133.75 ? 305 CYS D SG    1 
ATOM   12401 N  N     . ASP D 2 306 ? 387.915 391.241 199.179 1.00 115.34 ? 306 ASP D N     1 
ATOM   12402 C  CA    . ASP D 2 306 ? 387.161 391.901 198.124 1.00 120.14 ? 306 ASP D CA    1 
ATOM   12403 C  C     . ASP D 2 306 ? 388.008 391.934 196.853 1.00 121.26 ? 306 ASP D C     1 
ATOM   12404 O  O     . ASP D 2 306 ? 389.075 392.566 196.864 1.00 124.31 ? 306 ASP D O     1 
ATOM   12405 C  CB    . ASP D 2 306 ? 386.791 393.318 198.548 1.00 117.41 ? 306 ASP D CB    1 
ATOM   12406 C  CG    . ASP D 2 306 ? 385.647 393.891 197.736 1.00 123.29 ? 306 ASP D CG    1 
ATOM   12407 O  OD1   . ASP D 2 306 ? 385.364 393.362 196.641 1.00 127.30 ? 306 ASP D OD1   1 
ATOM   12408 O  OD2   . ASP D 2 306 ? 385.031 394.877 198.192 1.00 122.17 ? 306 ASP D OD2   1 
ATOM   12409 N  N     . PRO D 2 307 ? 387.594 391.304 195.741 1.00 117.44 ? 307 PRO D N     1 
ATOM   12410 C  CA    . PRO D 2 307 ? 388.403 391.418 194.514 1.00 118.62 ? 307 PRO D CA    1 
ATOM   12411 C  C     . PRO D 2 307 ? 388.498 392.835 193.984 1.00 123.30 ? 307 PRO D C     1 
ATOM   12412 O  O     . PRO D 2 307 ? 389.458 393.154 193.272 1.00 126.47 ? 307 PRO D O     1 
ATOM   12413 C  CB    . PRO D 2 307 ? 387.679 390.498 193.520 1.00 115.95 ? 307 PRO D CB    1 
ATOM   12414 C  CG    . PRO D 2 307 ? 386.853 389.602 194.348 1.00 119.88 ? 307 PRO D CG    1 
ATOM   12415 C  CD    . PRO D 2 307 ? 386.426 390.432 195.504 1.00 118.24 ? 307 PRO D CD    1 
ATOM   12416 N  N     . ARG D 2 308 ? 387.544 393.702 194.332 1.00 123.12 ? 308 ARG D N     1 
ATOM   12417 C  CA    . ARG D 2 308 ? 387.633 395.111 193.974 1.00 120.99 ? 308 ARG D CA    1 
ATOM   12418 C  C     . ARG D 2 308 ? 388.844 395.788 194.603 1.00 120.89 ? 308 ARG D C     1 
ATOM   12419 O  O     . ARG D 2 308 ? 389.324 396.791 194.065 1.00 120.47 ? 308 ARG D O     1 
ATOM   12420 C  CB    . ARG D 2 308 ? 386.352 395.841 194.389 1.00 121.11 ? 308 ARG D CB    1 
ATOM   12421 C  CG    . ARG D 2 308 ? 385.065 395.251 193.799 1.00 121.81 ? 308 ARG D CG    1 
ATOM   12422 C  CD    . ARG D 2 308 ? 383.810 395.988 194.257 1.00 123.65 ? 308 ARG D CD    1 
ATOM   12423 N  NE    . ARG D 2 308 ? 383.607 395.907 195.704 1.00 129.47 ? 308 ARG D NE    1 
ATOM   12424 C  CZ    . ARG D 2 308 ? 382.436 395.950 196.333 1.00 127.62 ? 308 ARG D CZ    1 
ATOM   12425 N  NH1   . ARG D 2 308 ? 381.290 396.110 195.683 1.00 126.96 ? 308 ARG D NH1   1 
ATOM   12426 N  NH2   . ARG D 2 308 ? 382.411 395.836 197.657 1.00 126.32 ? 308 ARG D NH2   1 
ATOM   12427 N  N     . HIS D 2 309 ? 389.353 395.268 195.726 1.00 119.61 ? 309 HIS D N     1 
ATOM   12428 C  CA    . HIS D 2 309 ? 390.586 395.800 196.296 1.00 119.31 ? 309 HIS D CA    1 
ATOM   12429 C  C     . HIS D 2 309 ? 391.829 395.420 195.499 1.00 116.51 ? 309 HIS D C     1 
ATOM   12430 O  O     . HIS D 2 309 ? 392.902 395.961 195.788 1.00 117.45 ? 309 HIS D O     1 
ATOM   12431 C  CB    . HIS D 2 309 ? 390.760 395.322 197.741 1.00 122.11 ? 309 HIS D CB    1 
ATOM   12432 C  CG    . HIS D 2 309 ? 389.754 395.881 198.702 1.00 121.66 ? 309 HIS D CG    1 
ATOM   12433 N  ND1   . HIS D 2 309 ? 388.998 397.003 198.433 1.00 121.68 ? 309 HIS D ND1   1 
ATOM   12434 C  CD2   . HIS D 2 309 ? 389.398 395.480 199.945 1.00 118.54 ? 309 HIS D CD2   1 
ATOM   12435 C  CE1   . HIS D 2 309 ? 388.210 397.258 199.461 1.00 121.32 ? 309 HIS D CE1   1 
ATOM   12436 N  NE2   . HIS D 2 309 ? 388.433 396.349 200.392 1.00 121.33 ? 309 HIS D NE2   1 
ATOM   12437 N  N     . GLY D 2 310 ? 391.721 394.509 194.527 1.00 111.77 ? 310 GLY D N     1 
ATOM   12438 C  CA    . GLY D 2 310 ? 392.851 394.106 193.710 1.00 114.91 ? 310 GLY D CA    1 
ATOM   12439 C  C     . GLY D 2 310 ? 392.467 393.899 192.261 1.00 114.94 ? 310 GLY D C     1 
ATOM   12440 O  O     . GLY D 2 310 ? 391.421 394.380 191.818 1.00 115.47 ? 310 GLY D O     1 
ATOM   12441 N  N     . LYS D 2 311 ? 393.319 393.193 191.517 1.00 111.82 ? 311 LYS D N     1 
ATOM   12442 C  CA    . LYS D 2 311 ? 393.097 392.878 190.114 1.00 109.08 ? 311 LYS D CA    1 
ATOM   12443 C  C     . LYS D 2 311 ? 393.287 391.388 189.893 1.00 109.59 ? 311 LYS D C     1 
ATOM   12444 O  O     . LYS D 2 311 ? 394.222 390.785 190.426 1.00 112.66 ? 311 LYS D O     1 
ATOM   12445 C  CB    . LYS D 2 311 ? 394.058 393.647 189.205 1.00 111.52 ? 311 LYS D CB    1 
ATOM   12446 C  CG    . LYS D 2 311 ? 393.828 395.143 189.162 1.00 112.50 ? 311 LYS D CG    1 
ATOM   12447 C  CD    . LYS D 2 311 ? 394.701 395.787 188.098 1.00 111.26 ? 311 LYS D CD    1 
ATOM   12448 C  CE    . LYS D 2 311 ? 394.489 397.286 188.025 1.00 112.96 ? 311 LYS D CE    1 
ATOM   12449 N  NZ    . LYS D 2 311 ? 395.060 397.988 189.204 1.00 115.32 ? 311 LYS D NZ    1 
ATOM   12450 N  N     . TYR D 2 312 ? 392.393 390.800 189.107 1.00 101.68 ? 312 TYR D N     1 
ATOM   12451 C  CA    . TYR D 2 312 ? 392.571 389.424 188.680 1.00 99.84  ? 312 TYR D CA    1 
ATOM   12452 C  C     . TYR D 2 312 ? 393.767 389.323 187.745 1.00 99.60  ? 312 TYR D C     1 
ATOM   12453 O  O     . TYR D 2 312 ? 394.090 390.264 187.016 1.00 103.13 ? 312 TYR D O     1 
ATOM   12454 C  CB    . TYR D 2 312 ? 391.317 388.920 187.968 1.00 102.86 ? 312 TYR D CB    1 
ATOM   12455 C  CG    . TYR D 2 312 ? 390.105 388.813 188.860 1.00 103.77 ? 312 TYR D CG    1 
ATOM   12456 C  CD1   . TYR D 2 312 ? 389.937 387.730 189.706 1.00 105.38 ? 312 TYR D CD1   1 
ATOM   12457 C  CD2   . TYR D 2 312 ? 389.130 389.799 188.858 1.00 102.61 ? 312 TYR D CD2   1 
ATOM   12458 C  CE1   . TYR D 2 312 ? 388.834 387.627 190.523 1.00 105.78 ? 312 TYR D CE1   1 
ATOM   12459 C  CE2   . TYR D 2 312 ? 388.022 389.705 189.671 1.00 104.64 ? 312 TYR D CE2   1 
ATOM   12460 C  CZ    . TYR D 2 312 ? 387.878 388.617 190.501 1.00 106.41 ? 312 TYR D CZ    1 
ATOM   12461 O  OH    . TYR D 2 312 ? 386.776 388.519 191.317 1.00 108.17 ? 312 TYR D OH    1 
ATOM   12462 N  N     . MET D 2 313 ? 394.441 388.170 187.791 1.00 106.53 ? 313 MET D N     1 
ATOM   12463 C  CA    . MET D 2 313 ? 395.481 387.837 186.826 1.00 109.24 ? 313 MET D CA    1 
ATOM   12464 C  C     . MET D 2 313 ? 395.349 386.438 186.248 1.00 109.51 ? 313 MET D C     1 
ATOM   12465 O  O     . MET D 2 313 ? 396.051 386.137 185.277 1.00 111.72 ? 313 MET D O     1 
ATOM   12466 C  CB    . MET D 2 313 ? 396.881 387.992 187.446 1.00 108.94 ? 313 MET D CB    1 
ATOM   12467 C  CG    . MET D 2 313 ? 397.281 386.898 188.449 1.00 112.38 ? 313 MET D CG    1 
ATOM   12468 S  SD    . MET D 2 313 ? 398.648 387.232 189.598 1.00 128.49 ? 313 MET D SD    1 
ATOM   12469 C  CE    . MET D 2 313 ? 398.311 388.870 190.235 1.00 115.73 ? 313 MET D CE    1 
ATOM   12470 N  N     . ALA D 2 314 ? 394.494 385.574 186.797 1.00 101.40 ? 314 ALA D N     1 
ATOM   12471 C  CA    . ALA D 2 314 ? 394.216 384.308 186.118 1.00 99.35  ? 314 ALA D CA    1 
ATOM   12472 C  C     . ALA D 2 314 ? 392.904 383.736 186.636 1.00 105.21 ? 314 ALA D C     1 
ATOM   12473 O  O     . ALA D 2 314 ? 392.845 383.278 187.777 1.00 113.89 ? 314 ALA D O     1 
ATOM   12474 C  CB    . ALA D 2 314 ? 395.359 383.322 186.324 1.00 106.53 ? 314 ALA D CB    1 
ATOM   12475 N  N     . CYS D 2 315 ? 391.878 383.726 185.789 1.00 118.83 ? 315 CYS D N     1 
ATOM   12476 C  CA    . CYS D 2 315 ? 390.579 383.153 186.112 1.00 120.15 ? 315 CYS D CA    1 
ATOM   12477 C  C     . CYS D 2 315 ? 390.393 381.860 185.332 1.00 120.04 ? 315 CYS D C     1 
ATOM   12478 O  O     . CYS D 2 315 ? 390.757 381.782 184.157 1.00 123.11 ? 315 CYS D O     1 
ATOM   12479 C  CB    . CYS D 2 315 ? 389.454 384.134 185.784 1.00 121.68 ? 315 CYS D CB    1 
ATOM   12480 S  SG    . CYS D 2 315 ? 389.173 385.353 187.080 1.00 134.35 ? 315 CYS D SG    1 
ATOM   12481 N  N     . CYS D 2 316 ? 389.841 380.846 185.997 1.00 104.24 ? 316 CYS D N     1 
ATOM   12482 C  CA    . CYS D 2 316 ? 389.622 379.530 185.408 1.00 104.45 ? 316 CYS D CA    1 
ATOM   12483 C  C     . CYS D 2 316 ? 388.262 379.024 185.856 1.00 108.78 ? 316 CYS D C     1 
ATOM   12484 O  O     . CYS D 2 316 ? 388.034 378.834 187.054 1.00 112.94 ? 316 CYS D O     1 
ATOM   12485 C  CB    . CYS D 2 316 ? 390.724 378.555 185.822 1.00 108.85 ? 316 CYS D CB    1 
ATOM   12486 S  SG    . CYS D 2 316 ? 390.477 376.855 185.264 1.00 113.83 ? 316 CYS D SG    1 
ATOM   12487 N  N     . LEU D 2 317 ? 387.371 378.803 184.894 1.00 98.94  ? 317 LEU D N     1 
ATOM   12488 C  CA    . LEU D 2 317 ? 385.987 378.423 185.145 1.00 96.97  ? 317 LEU D CA    1 
ATOM   12489 C  C     . LEU D 2 317 ? 385.740 377.018 184.624 1.00 100.66 ? 317 LEU D C     1 
ATOM   12490 O  O     . LEU D 2 317 ? 386.221 376.653 183.544 1.00 106.69 ? 317 LEU D O     1 
ATOM   12491 C  CB    . LEU D 2 317 ? 385.015 379.412 184.500 1.00 95.47  ? 317 LEU D CB    1 
ATOM   12492 C  CG    . LEU D 2 317 ? 384.700 380.688 185.298 1.00 102.22 ? 317 LEU D CG    1 
ATOM   12493 C  CD1   . LEU D 2 317 ? 385.913 381.345 185.926 1.00 106.70 ? 317 LEU D CD1   1 
ATOM   12494 C  CD2   . LEU D 2 317 ? 384.011 381.675 184.421 1.00 100.95 ? 317 LEU D CD2   1 
ATOM   12495 N  N     . LEU D 2 318 ? 384.991 376.243 185.406 1.00 98.38  ? 318 LEU D N     1 
ATOM   12496 C  CA    . LEU D 2 318 ? 384.776 374.818 185.184 1.00 97.89  ? 318 LEU D CA    1 
ATOM   12497 C  C     . LEU D 2 318 ? 383.267 374.616 185.213 1.00 102.42 ? 318 LEU D C     1 
ATOM   12498 O  O     . LEU D 2 318 ? 382.680 374.491 186.290 1.00 111.38 ? 318 LEU D O     1 
ATOM   12499 C  CB    . LEU D 2 318 ? 385.489 374.000 186.249 1.00 98.04  ? 318 LEU D CB    1 
ATOM   12500 C  CG    . LEU D 2 318 ? 386.986 374.298 186.409 1.00 98.43  ? 318 LEU D CG    1 
ATOM   12501 C  CD1   . LEU D 2 318 ? 387.557 373.551 187.589 1.00 105.73 ? 318 LEU D CD1   1 
ATOM   12502 C  CD2   . LEU D 2 318 ? 387.754 373.956 185.142 1.00 100.02 ? 318 LEU D CD2   1 
ATOM   12503 N  N     . TYR D 2 319 ? 382.652 374.655 184.035 1.00 100.14 ? 319 TYR D N     1 
ATOM   12504 C  CA    . TYR D 2 319 ? 381.228 374.423 183.883 1.00 98.33  ? 319 TYR D CA    1 
ATOM   12505 C  C     . TYR D 2 319 ? 380.933 372.933 183.777 1.00 101.74 ? 319 TYR D C     1 
ATOM   12506 O  O     . TYR D 2 319 ? 381.681 372.163 183.160 1.00 106.38 ? 319 TYR D O     1 
ATOM   12507 C  CB    . TYR D 2 319 ? 380.703 375.138 182.639 1.00 100.56 ? 319 TYR D CB    1 
ATOM   12508 C  CG    . TYR D 2 319 ? 380.787 376.644 182.707 1.00 100.79 ? 319 TYR D CG    1 
ATOM   12509 C  CD1   . TYR D 2 319 ? 381.920 377.318 182.277 1.00 102.01 ? 319 TYR D CD1   1 
ATOM   12510 C  CD2   . TYR D 2 319 ? 379.722 377.393 183.179 1.00 99.55  ? 319 TYR D CD2   1 
ATOM   12511 C  CE1   . TYR D 2 319 ? 381.994 378.695 182.334 1.00 103.21 ? 319 TYR D CE1   1 
ATOM   12512 C  CE2   . TYR D 2 319 ? 379.786 378.767 183.240 1.00 101.17 ? 319 TYR D CE2   1 
ATOM   12513 C  CZ    . TYR D 2 319 ? 380.922 379.414 182.815 1.00 104.68 ? 319 TYR D CZ    1 
ATOM   12514 O  OH    . TYR D 2 319 ? 380.984 380.786 182.874 1.00 106.60 ? 319 TYR D OH    1 
ATOM   12515 N  N     . ARG D 2 320 ? 379.810 372.535 184.369 1.00 112.73 ? 320 ARG D N     1 
ATOM   12516 C  CA    . ARG D 2 320 ? 379.401 371.141 184.376 1.00 111.07 ? 320 ARG D CA    1 
ATOM   12517 C  C     . ARG D 2 320 ? 377.887 371.062 184.269 1.00 114.67 ? 320 ARG D C     1 
ATOM   12518 O  O     . ARG D 2 320 ? 377.169 371.730 185.023 1.00 115.09 ? 320 ARG D O     1 
ATOM   12519 C  CB    . ARG D 2 320 ? 379.917 370.430 185.632 1.00 110.99 ? 320 ARG D CB    1 
ATOM   12520 C  CG    . ARG D 2 320 ? 379.314 370.880 186.943 1.00 111.90 ? 320 ARG D CG    1 
ATOM   12521 C  CD    . ARG D 2 320 ? 380.092 370.310 188.120 1.00 111.46 ? 320 ARG D CD    1 
ATOM   12522 N  NE    . ARG D 2 320 ? 380.102 368.849 188.112 1.00 112.89 ? 320 ARG D NE    1 
ATOM   12523 C  CZ    . ARG D 2 320 ? 380.411 368.075 189.146 1.00 116.62 ? 320 ARG D CZ    1 
ATOM   12524 N  NH1   . ARG D 2 320 ? 380.750 368.578 190.324 1.00 117.90 ? 320 ARG D NH1   1 
ATOM   12525 N  NH2   . ARG D 2 320 ? 380.385 366.754 188.992 1.00 114.56 ? 320 ARG D NH2   1 
ATOM   12526 N  N     . GLY D 2 321 ? 377.420 370.260 183.309 1.00 120.86 ? 321 GLY D N     1 
ATOM   12527 C  CA    . GLY D 2 321 ? 376.006 370.019 183.092 1.00 121.79 ? 321 GLY D CA    1 
ATOM   12528 C  C     . GLY D 2 321 ? 375.568 370.490 181.713 1.00 121.05 ? 321 GLY D C     1 
ATOM   12529 O  O     . GLY D 2 321 ? 376.338 370.422 180.744 1.00 119.13 ? 321 GLY D O     1 
ATOM   12530 N  N     . ASP D 2 322 ? 374.329 370.967 181.631 1.00 137.05 ? 322 ASP D N     1 
ATOM   12531 C  CA    . ASP D 2 322 ? 373.728 371.387 180.366 1.00 140.19 ? 322 ASP D CA    1 
ATOM   12532 C  C     . ASP D 2 322 ? 374.236 372.784 180.035 1.00 139.54 ? 322 ASP D C     1 
ATOM   12533 O  O     . ASP D 2 322 ? 373.617 373.793 180.374 1.00 139.95 ? 322 ASP D O     1 
ATOM   12534 C  CB    . ASP D 2 322 ? 372.207 371.350 180.457 1.00 141.23 ? 322 ASP D CB    1 
ATOM   12535 C  CG    . ASP D 2 322 ? 371.533 371.962 179.245 1.00 143.76 ? 322 ASP D CG    1 
ATOM   12536 O  OD1   . ASP D 2 322 ? 371.977 371.683 178.111 1.00 143.91 ? 322 ASP D OD1   1 
ATOM   12537 O  OD2   . ASP D 2 322 ? 370.562 372.725 179.427 1.00 141.20 ? 322 ASP D OD2   1 
ATOM   12538 N  N     . VAL D 2 323 ? 375.384 372.834 179.360 1.00 110.03 ? 323 VAL D N     1 
ATOM   12539 C  CA    . VAL D 2 323 ? 376.061 374.079 179.012 1.00 105.63 ? 323 VAL D CA    1 
ATOM   12540 C  C     . VAL D 2 323 ? 376.536 373.975 177.572 1.00 107.85 ? 323 VAL D C     1 
ATOM   12541 O  O     . VAL D 2 323 ? 377.010 372.917 177.143 1.00 112.38 ? 323 VAL D O     1 
ATOM   12542 C  CB    . VAL D 2 323 ? 377.243 374.366 179.964 1.00 101.27 ? 323 VAL D CB    1 
ATOM   12543 C  CG1   . VAL D 2 323 ? 377.970 375.644 179.549 1.00 108.69 ? 323 VAL D CG1   1 
ATOM   12544 C  CG2   . VAL D 2 323 ? 376.753 374.452 181.410 1.00 104.66 ? 323 VAL D CG2   1 
ATOM   12545 N  N     . VAL D 2 324 ? 376.415 375.079 176.835 1.00 101.81 ? 324 VAL D N     1 
ATOM   12546 C  CA    . VAL D 2 324 ? 376.817 375.169 175.428 1.00 104.86 ? 324 VAL D CA    1 
ATOM   12547 C  C     . VAL D 2 324 ? 378.015 376.112 175.338 1.00 105.66 ? 324 VAL D C     1 
ATOM   12548 O  O     . VAL D 2 324 ? 378.163 376.981 176.210 1.00 108.61 ? 324 VAL D O     1 
ATOM   12549 C  CB    . VAL D 2 324 ? 375.661 375.640 174.526 1.00 107.59 ? 324 VAL D CB    1 
ATOM   12550 C  CG1   . VAL D 2 324 ? 374.651 374.520 174.334 1.00 112.98 ? 324 VAL D CG1   1 
ATOM   12551 C  CG2   . VAL D 2 324 ? 374.965 376.887 175.075 1.00 107.04 ? 324 VAL D CG2   1 
ATOM   12552 N  N     . PRO D 2 325 ? 378.900 375.988 174.338 1.00 112.15 ? 325 PRO D N     1 
ATOM   12553 C  CA    . PRO D 2 325 ? 380.059 376.898 174.294 1.00 113.16 ? 325 PRO D CA    1 
ATOM   12554 C  C     . PRO D 2 325 ? 379.698 378.357 174.064 1.00 112.72 ? 325 PRO D C     1 
ATOM   12555 O  O     . PRO D 2 325 ? 380.384 379.243 174.588 1.00 117.44 ? 325 PRO D O     1 
ATOM   12556 C  CB    . PRO D 2 325 ? 380.900 376.346 173.132 1.00 119.04 ? 325 PRO D CB    1 
ATOM   12557 C  CG    . PRO D 2 325 ? 380.404 374.974 172.898 1.00 119.52 ? 325 PRO D CG    1 
ATOM   12558 C  CD    . PRO D 2 325 ? 378.957 375.013 173.233 1.00 120.28 ? 325 PRO D CD    1 
ATOM   12559 N  N     . LYS D 2 326 ? 378.651 378.642 173.287 1.00 92.11  ? 326 LYS D N     1 
ATOM   12560 C  CA    . LYS D 2 326 ? 378.366 380.031 172.932 1.00 94.09  ? 326 LYS D CA    1 
ATOM   12561 C  C     . LYS D 2 326 ? 377.858 380.823 174.128 1.00 96.26  ? 326 LYS D C     1 
ATOM   12562 O  O     . LYS D 2 326 ? 378.171 382.012 174.261 1.00 99.54  ? 326 LYS D O     1 
ATOM   12563 C  CB    . LYS D 2 326 ? 377.353 380.103 171.782 1.00 96.95  ? 326 LYS D CB    1 
ATOM   12564 C  CG    . LYS D 2 326 ? 376.974 381.505 171.212 1.00 104.12 ? 326 LYS D CG    1 
ATOM   12565 C  CD    . LYS D 2 326 ? 375.986 381.574 170.019 1.00 100.53 ? 326 LYS D CD    1 
ATOM   12566 C  CE    . LYS D 2 326 ? 375.721 383.017 169.621 1.00 90.02  ? 326 LYS D CE    1 
ATOM   12567 N  NZ    . LYS D 2 326 ? 374.776 383.108 168.478 1.00 96.26  ? 326 LYS D NZ    1 
ATOM   12568 N  N     . ASP D 2 327 ? 377.072 380.193 175.002 1.00 111.72 ? 327 ASP D N     1 
ATOM   12569 C  CA    . ASP D 2 327 ? 376.577 380.896 176.182 1.00 116.28 ? 327 ASP D CA    1 
ATOM   12570 C  C     . ASP D 2 327 ? 377.727 381.302 177.096 1.00 114.98 ? 327 ASP D C     1 
ATOM   12571 O  O     . ASP D 2 327 ? 377.797 382.453 177.549 1.00 119.06 ? 327 ASP D O     1 
ATOM   12572 C  CB    . ASP D 2 327 ? 375.575 380.020 176.935 1.00 118.64 ? 327 ASP D CB    1 
ATOM   12573 C  CG    . ASP D 2 327 ? 374.241 379.912 176.222 1.00 122.99 ? 327 ASP D CG    1 
ATOM   12574 O  OD1   . ASP D 2 327 ? 374.139 380.368 175.064 1.00 122.37 ? 327 ASP D OD1   1 
ATOM   12575 O  OD2   . ASP D 2 327 ? 373.290 379.367 176.822 1.00 121.13 ? 327 ASP D OD2   1 
ATOM   12576 N  N     . VAL D 2 328 ? 378.657 380.379 177.352 1.00 108.46 ? 328 VAL D N     1 
ATOM   12577 C  CA    . VAL D 2 328 ? 379.803 380.718 178.190 1.00 108.29 ? 328 VAL D CA    1 
ATOM   12578 C  C     . VAL D 2 328 ? 380.690 381.740 177.492 1.00 108.27 ? 328 VAL D C     1 
ATOM   12579 O  O     . VAL D 2 328 ? 381.241 382.629 178.140 1.00 117.47 ? 328 VAL D O     1 
ATOM   12580 C  CB    . VAL D 2 328 ? 380.598 379.461 178.609 1.00 108.48 ? 328 VAL D CB    1 
ATOM   12581 C  CG1   . VAL D 2 328 ? 379.755 378.570 179.500 1.00 112.89 ? 328 VAL D CG1   1 
ATOM   12582 C  CG2   . VAL D 2 328 ? 381.117 378.659 177.420 1.00 111.79 ? 328 VAL D CG2   1 
ATOM   12583 N  N     . ASN D 2 329 ? 380.833 381.649 176.167 1.00 113.24 ? 329 ASN D N     1 
ATOM   12584 C  CA    . ASN D 2 329 ? 381.683 382.601 175.458 1.00 114.92 ? 329 ASN D CA    1 
ATOM   12585 C  C     . ASN D 2 329 ? 381.116 384.014 175.548 1.00 116.35 ? 329 ASN D C     1 
ATOM   12586 O  O     . ASN D 2 329 ? 381.846 384.975 175.825 1.00 120.77 ? 329 ASN D O     1 
ATOM   12587 C  CB    . ASN D 2 329 ? 381.843 382.169 174.000 1.00 119.22 ? 329 ASN D CB    1 
ATOM   12588 C  CG    . ASN D 2 329 ? 382.611 383.178 173.174 1.00 123.80 ? 329 ASN D CG    1 
ATOM   12589 O  OD1   . ASN D 2 329 ? 383.842 383.191 173.176 1.00 124.31 ? 329 ASN D OD1   1 
ATOM   12590 N  ND2   . ASN D 2 329 ? 381.888 384.027 172.454 1.00 122.58 ? 329 ASN D ND2   1 
ATOM   12591 N  N     . ALA D 2 330 ? 379.802 384.151 175.351 1.00 108.31 ? 330 ALA D N     1 
ATOM   12592 C  CA    . ALA D 2 330 ? 379.162 385.455 175.484 1.00 110.71 ? 330 ALA D CA    1 
ATOM   12593 C  C     . ALA D 2 330 ? 379.263 385.976 176.911 1.00 114.12 ? 330 ALA D C     1 
ATOM   12594 O  O     . ALA D 2 330 ? 379.548 387.161 177.128 1.00 122.09 ? 330 ALA D O     1 
ATOM   12595 C  CB    . ALA D 2 330 ? 377.700 385.363 175.047 1.00 109.88 ? 330 ALA D CB    1 
ATOM   12596 N  N     . ALA D 2 331 ? 379.053 385.100 177.900 1.00 103.27 ? 331 ALA D N     1 
ATOM   12597 C  CA    . ALA D 2 331 ? 379.139 385.525 179.293 1.00 101.93 ? 331 ALA D CA    1 
ATOM   12598 C  C     . ALA D 2 331 ? 380.550 385.980 179.655 1.00 107.50 ? 331 ALA D C     1 
ATOM   12599 O  O     . ALA D 2 331 ? 380.720 386.965 180.382 1.00 111.85 ? 331 ALA D O     1 
ATOM   12600 C  CB    . ALA D 2 331 ? 378.692 384.389 180.211 1.00 103.42 ? 331 ALA D CB    1 
ATOM   12601 N  N     . ILE D 2 332 ? 381.575 385.279 179.165 1.00 116.23 ? 332 ILE D N     1 
ATOM   12602 C  CA    . ILE D 2 332 ? 382.944 385.636 179.522 1.00 112.14 ? 332 ILE D CA    1 
ATOM   12603 C  C     . ILE D 2 332 ? 383.345 386.921 178.813 1.00 118.04 ? 332 ILE D C     1 
ATOM   12604 O  O     . ILE D 2 332 ? 384.075 387.744 179.376 1.00 125.40 ? 332 ILE D O     1 
ATOM   12605 C  CB    . ILE D 2 332 ? 383.908 384.469 179.200 1.00 115.92 ? 332 ILE D CB    1 
ATOM   12606 C  CG1   . ILE D 2 332 ? 383.740 383.252 180.156 1.00 120.54 ? 332 ILE D CG1   1 
ATOM   12607 C  CG2   . ILE D 2 332 ? 385.394 384.952 179.206 1.00 120.40 ? 332 ILE D CG2   1 
ATOM   12608 C  CD1   . ILE D 2 332 ? 383.499 383.458 181.638 1.00 120.52 ? 332 ILE D CD1   1 
ATOM   12609 N  N     . ALA D 2 333 ? 382.880 387.121 177.573 1.00 109.89 ? 333 ALA D N     1 
ATOM   12610 C  CA    . ALA D 2 333 ? 383.096 388.407 176.916 1.00 108.72 ? 333 ALA D CA    1 
ATOM   12611 C  C     . ALA D 2 333 ? 382.447 389.537 177.706 1.00 109.52 ? 333 ALA D C     1 
ATOM   12612 O  O     . ALA D 2 333 ? 383.039 390.608 177.873 1.00 115.78 ? 333 ALA D O     1 
ATOM   12613 C  CB    . ALA D 2 333 ? 382.552 388.372 175.489 1.00 105.62 ? 333 ALA D CB    1 
ATOM   12614 N  N     . THR D 2 334 ? 381.243 389.297 178.230 1.00 111.44 ? 334 THR D N     1 
ATOM   12615 C  CA    . THR D 2 334 ? 380.560 390.299 179.043 1.00 114.09 ? 334 THR D CA    1 
ATOM   12616 C  C     . THR D 2 334 ? 381.357 390.615 180.308 1.00 115.62 ? 334 THR D C     1 
ATOM   12617 O  O     . THR D 2 334 ? 381.575 391.786 180.651 1.00 119.05 ? 334 THR D O     1 
ATOM   12618 C  CB    . THR D 2 334 ? 379.155 389.786 179.388 1.00 112.71 ? 334 THR D CB    1 
ATOM   12619 O  OG1   . THR D 2 334 ? 378.471 389.431 178.180 1.00 115.89 ? 334 THR D OG1   1 
ATOM   12620 C  CG2   . THR D 2 334 ? 378.311 390.837 180.123 1.00 110.70 ? 334 THR D CG2   1 
ATOM   12621 N  N     . ILE D 2 335 ? 381.807 389.572 181.010 1.00 121.41 ? 335 ILE D N     1 
ATOM   12622 C  CA    . ILE D 2 335 ? 382.525 389.765 182.268 1.00 117.74 ? 335 ILE D CA    1 
ATOM   12623 C  C     . ILE D 2 335 ? 383.854 390.463 182.021 1.00 117.83 ? 335 ILE D C     1 
ATOM   12624 O  O     . ILE D 2 335 ? 384.295 391.277 182.840 1.00 117.67 ? 335 ILE D O     1 
ATOM   12625 C  CB    . ILE D 2 335 ? 382.715 388.414 182.990 1.00 119.74 ? 335 ILE D CB    1 
ATOM   12626 C  CG1   . ILE D 2 335 ? 381.370 387.850 183.473 1.00 121.67 ? 335 ILE D CG1   1 
ATOM   12627 C  CG2   . ILE D 2 335 ? 383.689 388.538 184.168 1.00 117.48 ? 335 ILE D CG2   1 
ATOM   12628 C  CD1   . ILE D 2 335 ? 380.789 388.510 184.722 1.00 120.36 ? 335 ILE D CD1   1 
ATOM   12629 N  N     . LYS D 2 336 ? 384.515 390.161 180.903 1.00 119.20 ? 336 LYS D N     1 
ATOM   12630 C  CA    . LYS D 2 336 ? 385.715 390.899 180.530 1.00 116.30 ? 336 LYS D CA    1 
ATOM   12631 C  C     . LYS D 2 336 ? 385.389 392.357 180.228 1.00 116.97 ? 336 LYS D C     1 
ATOM   12632 O  O     . LYS D 2 336 ? 386.179 393.255 180.542 1.00 117.62 ? 336 LYS D O     1 
ATOM   12633 C  CB    . LYS D 2 336 ? 386.373 390.233 179.321 1.00 115.75 ? 336 LYS D CB    1 
ATOM   12634 C  CG    . LYS D 2 336 ? 387.848 390.551 179.147 1.00 120.27 ? 336 LYS D CG    1 
ATOM   12635 C  CD    . LYS D 2 336 ? 388.465 389.742 178.007 1.00 119.63 ? 336 LYS D CD    1 
ATOM   12636 C  CE    . LYS D 2 336 ? 388.036 390.260 176.638 1.00 118.29 ? 336 LYS D CE    1 
ATOM   12637 N  NZ    . LYS D 2 336 ? 388.804 389.625 175.527 1.00 121.41 ? 336 LYS D NZ    1 
ATOM   12638 N  N     . THR D 2 337 ? 384.227 392.608 179.620 1.00 122.80 ? 337 THR D N     1 
ATOM   12639 C  CA    . THR D 2 337 ? 383.892 393.959 179.183 1.00 121.83 ? 337 THR D CA    1 
ATOM   12640 C  C     . THR D 2 337 ? 383.559 394.877 180.354 1.00 122.72 ? 337 THR D C     1 
ATOM   12641 O  O     . THR D 2 337 ? 383.920 396.059 180.333 1.00 122.58 ? 337 THR D O     1 
ATOM   12642 C  CB    . THR D 2 337 ? 382.728 393.909 178.193 1.00 124.32 ? 337 THR D CB    1 
ATOM   12643 O  OG1   . THR D 2 337 ? 383.082 393.092 177.070 1.00 126.54 ? 337 THR D OG1   1 
ATOM   12644 C  CG2   . THR D 2 337 ? 382.364 395.306 177.714 1.00 123.93 ? 337 THR D CG2   1 
ATOM   12645 N  N     . LYS D 2 338 ? 382.951 394.313 181.406 1.00 129.07 ? 338 LYS D N     1 
ATOM   12646 C  CA    . LYS D 2 338 ? 382.551 395.107 182.603 1.00 130.35 ? 338 LYS D CA    1 
ATOM   12647 C  C     . LYS D 2 338 ? 383.737 395.910 183.152 1.00 131.11 ? 338 LYS D C     1 
ATOM   12648 O  O     . LYS D 2 338 ? 384.887 395.452 182.994 1.00 129.31 ? 338 LYS D O     1 
ATOM   12649 C  CB    . LYS D 2 338 ? 381.996 394.184 183.691 1.00 127.84 ? 338 LYS D CB    1 
ATOM   12650 C  CG    . LYS D 2 338 ? 381.481 394.875 184.948 1.00 130.21 ? 338 LYS D CG    1 
ATOM   12651 C  CD    . LYS D 2 338 ? 380.897 393.928 185.978 1.00 131.82 ? 338 LYS D CD    1 
ATOM   12652 C  CE    . LYS D 2 338 ? 380.412 394.625 187.232 1.00 130.06 ? 338 LYS D CE    1 
ATOM   12653 N  NZ    . LYS D 2 338 ? 379.850 393.666 188.211 1.00 127.11 ? 338 LYS D NZ    1 
ATOM   12654 N  N     . ARG D 2 339 ? 383.458 397.041 183.811 1.00 139.05 ? 339 ARG D N     1 
ATOM   12655 C  CA    . ARG D 2 339 ? 384.543 397.921 184.329 1.00 139.59 ? 339 ARG D CA    1 
ATOM   12656 C  C     . ARG D 2 339 ? 384.717 397.729 185.841 1.00 135.84 ? 339 ARG D C     1 
ATOM   12657 O  O     . ARG D 2 339 ? 385.832 397.994 186.331 1.00 135.14 ? 339 ARG D O     1 
ATOM   12658 C  CB    . ARG D 2 339 ? 384.235 399.384 183.995 1.00 141.63 ? 339 ARG D CB    1 
ATOM   12659 C  CG    . ARG D 2 339 ? 384.279 399.698 182.507 1.00 142.04 ? 339 ARG D CG    1 
ATOM   12660 C  CD    . ARG D 2 339 ? 384.018 401.162 182.213 1.00 143.71 ? 339 ARG D CD    1 
ATOM   12661 N  NE    . ARG D 2 339 ? 383.993 401.434 180.783 1.00 145.17 ? 339 ARG D NE    1 
ATOM   12662 C  CZ    . ARG D 2 339 ? 383.674 402.605 180.245 1.00 141.54 ? 339 ARG D CZ    1 
ATOM   12663 N  NH1   . ARG D 2 339 ? 383.355 403.625 181.022 1.00 134.85 ? 339 ARG D NH1   1 
ATOM   12664 N  NH2   . ARG D 2 339 ? 383.674 402.752 178.931 1.00 138.42 ? 339 ARG D NH2   1 
ATOM   12665 N  N     . SER D 2 340 ? 383.664 397.313 186.554 1.00 128.42 ? 340 SER D N     1 
ATOM   12666 C  CA    . SER D 2 340 ? 383.796 397.026 188.008 1.00 128.72 ? 340 SER D CA    1 
ATOM   12667 C  C     . SER D 2 340 ? 384.967 396.062 188.203 1.00 128.26 ? 340 SER D C     1 
ATOM   12668 O  O     . SER D 2 340 ? 385.969 396.471 188.822 1.00 127.78 ? 340 SER D O     1 
ATOM   12669 C  CB    . SER D 2 340 ? 382.519 396.462 188.568 1.00 130.70 ? 340 SER D CB    1 
ATOM   12670 O  OG    . SER D 2 340 ? 381.438 397.357 188.356 1.00 132.42 ? 340 SER D OG    1 
ATOM   12671 N  N     . ILE D 2 341 ? 384.837 394.829 187.708 1.00 127.49 ? 341 ILE D N     1 
ATOM   12672 C  CA    . ILE D 2 341 ? 385.942 393.881 187.743 1.00 126.86 ? 341 ILE D CA    1 
ATOM   12673 C  C     . ILE D 2 341 ? 387.120 394.535 187.037 1.00 125.14 ? 341 ILE D C     1 
ATOM   12674 O  O     . ILE D 2 341 ? 386.929 395.369 186.144 1.00 125.22 ? 341 ILE D O     1 
ATOM   12675 C  CB    . ILE D 2 341 ? 385.548 392.542 187.091 1.00 125.15 ? 341 ILE D CB    1 
ATOM   12676 C  CG1   . ILE D 2 341 ? 385.244 392.661 185.583 1.00 128.58 ? 341 ILE D CG1   1 
ATOM   12677 C  CG2   . ILE D 2 341 ? 384.332 391.968 187.791 1.00 121.84 ? 341 ILE D CG2   1 
ATOM   12678 C  CD1   . ILE D 2 341 ? 386.430 392.427 184.612 1.00 127.04 ? 341 ILE D CD1   1 
ATOM   12679 N  N     . GLN D 2 342 ? 388.333 394.170 187.441 1.00 113.09 ? 342 GLN D N     1 
ATOM   12680 C  CA    . GLN D 2 342 ? 389.551 394.650 186.807 1.00 111.89 ? 342 GLN D CA    1 
ATOM   12681 C  C     . GLN D 2 342 ? 390.566 393.522 186.700 1.00 107.31 ? 342 GLN D C     1 
ATOM   12682 O  O     . GLN D 2 342 ? 390.684 392.680 187.594 1.00 112.75 ? 342 GLN D O     1 
ATOM   12683 C  CB    . GLN D 2 342 ? 390.146 395.832 187.577 1.00 115.18 ? 342 GLN D CB    1 
ATOM   12684 C  CG    . GLN D 2 342 ? 389.230 397.055 187.620 1.00 116.31 ? 342 GLN D CG    1 
ATOM   12685 C  CD    . GLN D 2 342 ? 389.971 398.361 187.845 1.00 118.08 ? 342 GLN D CD    1 
ATOM   12686 O  OE1   . GLN D 2 342 ? 391.166 398.375 188.128 1.00 117.13 ? 342 GLN D OE1   1 
ATOM   12687 N  NE2   . GLN D 2 342 ? 389.260 399.473 187.695 1.00 120.19 ? 342 GLN D NE2   1 
ATOM   12688 N  N     . PHE D 2 343 ? 391.298 393.532 185.587 1.00 100.92 ? 343 PHE D N     1 
ATOM   12689 C  CA    . PHE D 2 343 ? 392.319 392.547 185.269 1.00 107.03 ? 343 PHE D CA    1 
ATOM   12690 C  C     . PHE D 2 343 ? 393.635 393.260 185.009 1.00 112.56 ? 343 PHE D C     1 
ATOM   12691 O  O     . PHE D 2 343 ? 393.658 394.433 184.630 1.00 115.00 ? 343 PHE D O     1 
ATOM   12692 C  CB    . PHE D 2 343 ? 391.933 391.716 184.038 1.00 107.84 ? 343 PHE D CB    1 
ATOM   12693 C  CG    . PHE D 2 343 ? 391.024 390.563 184.341 1.00 108.97 ? 343 PHE D CG    1 
ATOM   12694 C  CD1   . PHE D 2 343 ? 389.712 390.775 184.722 1.00 107.63 ? 343 PHE D CD1   1 
ATOM   12695 C  CD2   . PHE D 2 343 ? 391.478 389.262 184.214 1.00 114.06 ? 343 PHE D CD2   1 
ATOM   12696 C  CE1   . PHE D 2 343 ? 388.877 389.711 184.995 1.00 108.55 ? 343 PHE D CE1   1 
ATOM   12697 C  CE2   . PHE D 2 343 ? 390.648 388.196 184.480 1.00 118.59 ? 343 PHE D CE2   1 
ATOM   12698 C  CZ    . PHE D 2 343 ? 389.345 388.420 184.871 1.00 116.01 ? 343 PHE D CZ    1 
ATOM   12699 N  N     . VAL D 2 344 ? 394.736 392.544 185.231 1.00 111.62 ? 344 VAL D N     1 
ATOM   12700 C  CA    . VAL D 2 344 ? 396.051 393.098 184.938 1.00 107.93 ? 344 VAL D CA    1 
ATOM   12701 C  C     . VAL D 2 344 ? 396.199 393.282 183.434 1.00 110.92 ? 344 VAL D C     1 
ATOM   12702 O  O     . VAL D 2 344 ? 395.773 392.434 182.638 1.00 109.68 ? 344 VAL D O     1 
ATOM   12703 C  CB    . VAL D 2 344 ? 397.170 392.202 185.500 1.00 102.43 ? 344 VAL D CB    1 
ATOM   12704 C  CG1   . VAL D 2 344 ? 397.060 392.094 187.014 1.00 100.82 ? 344 VAL D CG1   1 
ATOM   12705 C  CG2   . VAL D 2 344 ? 397.190 390.815 184.835 1.00 111.40 ? 344 VAL D CG2   1 
ATOM   12706 N  N     . ASP D 2 345 ? 396.802 394.404 183.037 1.00 120.62 ? 345 ASP D N     1 
ATOM   12707 C  CA    . ASP D 2 345 ? 396.987 394.686 181.616 1.00 119.76 ? 345 ASP D CA    1 
ATOM   12708 C  C     . ASP D 2 345 ? 397.947 393.702 180.957 1.00 121.84 ? 345 ASP D C     1 
ATOM   12709 O  O     . ASP D 2 345 ? 397.820 393.427 179.759 1.00 123.99 ? 345 ASP D O     1 
ATOM   12710 C  CB    . ASP D 2 345 ? 397.494 396.114 181.426 1.00 119.28 ? 345 ASP D CB    1 
ATOM   12711 C  CG    . ASP D 2 345 ? 398.854 396.336 182.052 1.00 124.91 ? 345 ASP D CG    1 
ATOM   12712 O  OD1   . ASP D 2 345 ? 398.977 396.157 183.281 1.00 125.07 ? 345 ASP D OD1   1 
ATOM   12713 O  OD2   . ASP D 2 345 ? 399.800 396.685 181.316 1.00 125.82 ? 345 ASP D OD2   1 
ATOM   12714 N  N     . TRP D 2 346 ? 398.906 393.162 181.710 1.00 108.21 ? 346 TRP D N     1 
ATOM   12715 C  CA    . TRP D 2 346 ? 399.899 392.249 181.145 1.00 107.75 ? 346 TRP D CA    1 
ATOM   12716 C  C     . TRP D 2 346 ? 399.374 390.832 180.914 1.00 107.24 ? 346 TRP D C     1 
ATOM   12717 O  O     . TRP D 2 346 ? 400.162 389.967 180.517 1.00 108.03 ? 346 TRP D O     1 
ATOM   12718 C  CB    . TRP D 2 346 ? 401.156 392.190 182.034 1.00 104.73 ? 346 TRP D CB    1 
ATOM   12719 C  CG    . TRP D 2 346 ? 400.931 391.808 183.474 1.00 100.08 ? 346 TRP D CG    1 
ATOM   12720 C  CD1   . TRP D 2 346 ? 400.794 392.660 184.527 1.00 103.38 ? 346 TRP D CD1   1 
ATOM   12721 C  CD2   . TRP D 2 346 ? 400.829 390.485 184.013 1.00 96.59  ? 346 TRP D CD2   1 
ATOM   12722 N  NE1   . TRP D 2 346 ? 400.609 391.954 185.689 1.00 104.94 ? 346 TRP D NE1   1 
ATOM   12723 C  CE2   . TRP D 2 346 ? 400.626 390.615 185.400 1.00 98.83  ? 346 TRP D CE2   1 
ATOM   12724 C  CE3   . TRP D 2 346 ? 400.887 389.203 183.459 1.00 100.77 ? 346 TRP D CE3   1 
ATOM   12725 C  CZ2   . TRP D 2 346 ? 400.481 389.515 186.240 1.00 101.75 ? 346 TRP D CZ2   1 
ATOM   12726 C  CZ3   . TRP D 2 346 ? 400.742 388.112 184.295 1.00 104.45 ? 346 TRP D CZ3   1 
ATOM   12727 C  CH2   . TRP D 2 346 ? 400.542 388.275 185.670 1.00 104.97 ? 346 TRP D CH2   1 
ATOM   12728 N  N     . CYS D 2 347 ? 398.082 390.572 181.142 1.00 113.17 ? 347 CYS D N     1 
ATOM   12729 C  CA    . CYS D 2 347 ? 397.433 389.300 180.821 1.00 106.82 ? 347 CYS D CA    1 
ATOM   12730 C  C     . CYS D 2 347 ? 396.224 389.611 179.946 1.00 107.55 ? 347 CYS D C     1 
ATOM   12731 O  O     . CYS D 2 347 ? 395.114 389.796 180.469 1.00 111.20 ? 347 CYS D O     1 
ATOM   12732 C  CB    . CYS D 2 347 ? 397.015 388.557 182.085 1.00 109.10 ? 347 CYS D CB    1 
ATOM   12733 S  SG    . CYS D 2 347 ? 396.206 386.980 181.748 1.00 128.96 ? 347 CYS D SG    1 
ATOM   12734 N  N     . PRO D 2 348 ? 396.390 389.720 178.619 1.00 97.84  ? 348 PRO D N     1 
ATOM   12735 C  CA    . PRO D 2 348 ? 395.224 390.015 177.765 1.00 102.42 ? 348 PRO D CA    1 
ATOM   12736 C  C     . PRO D 2 348 ? 394.128 388.966 177.824 1.00 100.87 ? 348 PRO D C     1 
ATOM   12737 O  O     . PRO D 2 348 ? 392.946 389.322 177.737 1.00 99.99  ? 348 PRO D O     1 
ATOM   12738 C  CB    . PRO D 2 348 ? 395.831 390.104 176.357 1.00 107.04 ? 348 PRO D CB    1 
ATOM   12739 C  CG    . PRO D 2 348 ? 397.262 390.387 176.567 1.00 105.95 ? 348 PRO D CG    1 
ATOM   12740 C  CD    . PRO D 2 348 ? 397.638 389.701 177.834 1.00 101.04 ? 348 PRO D CD    1 
ATOM   12741 N  N     . THR D 2 349 ? 394.484 387.692 177.975 1.00 117.33 ? 349 THR D N     1 
ATOM   12742 C  CA    . THR D 2 349 ? 393.543 386.573 178.027 1.00 117.84 ? 349 THR D CA    1 
ATOM   12743 C  C     . THR D 2 349 ? 393.623 385.977 179.427 1.00 121.77 ? 349 THR D C     1 
ATOM   12744 O  O     . THR D 2 349 ? 394.471 385.124 179.701 1.00 123.82 ? 349 THR D O     1 
ATOM   12745 C  CB    . THR D 2 349 ? 393.865 385.535 176.960 1.00 123.93 ? 349 THR D CB    1 
ATOM   12746 O  OG1   . THR D 2 349 ? 395.251 385.179 177.038 1.00 123.34 ? 349 THR D OG1   1 
ATOM   12747 C  CG2   . THR D 2 349 ? 393.562 386.083 175.575 1.00 124.01 ? 349 THR D CG2   1 
ATOM   12748 N  N     . GLY D 2 350 ? 392.736 386.431 180.307 1.00 118.37 ? 350 GLY D N     1 
ATOM   12749 C  CA    . GLY D 2 350 ? 392.697 386.007 181.690 1.00 120.48 ? 350 GLY D CA    1 
ATOM   12750 C  C     . GLY D 2 350 ? 391.709 384.910 182.017 1.00 118.39 ? 350 GLY D C     1 
ATOM   12751 O  O     . GLY D 2 350 ? 391.487 384.649 183.205 1.00 122.02 ? 350 GLY D O     1 
ATOM   12752 N  N     . PHE D 2 351 ? 391.119 384.255 181.016 1.00 110.01 ? 351 PHE D N     1 
ATOM   12753 C  CA    . PHE D 2 351 ? 390.072 383.257 181.210 1.00 107.42 ? 351 PHE D CA    1 
ATOM   12754 C  C     . PHE D 2 351 ? 390.499 381.915 180.635 1.00 112.71 ? 351 PHE D C     1 
ATOM   12755 O  O     . PHE D 2 351 ? 390.925 381.833 179.478 1.00 115.35 ? 351 PHE D O     1 
ATOM   12756 C  CB    . PHE D 2 351 ? 388.765 383.711 180.563 1.00 105.25 ? 351 PHE D CB    1 
ATOM   12757 C  CG    . PHE D 2 351 ? 388.260 385.018 181.088 1.00 110.68 ? 351 PHE D CG    1 
ATOM   12758 C  CD1   . PHE D 2 351 ? 387.604 385.079 182.304 1.00 104.71 ? 351 PHE D CD1   1 
ATOM   12759 C  CD2   . PHE D 2 351 ? 388.441 386.187 180.370 1.00 120.11 ? 351 PHE D CD2   1 
ATOM   12760 C  CE1   . PHE D 2 351 ? 387.137 386.280 182.795 1.00 112.13 ? 351 PHE D CE1   1 
ATOM   12761 C  CE2   . PHE D 2 351 ? 387.975 387.390 180.856 1.00 119.61 ? 351 PHE D CE2   1 
ATOM   12762 C  CZ    . PHE D 2 351 ? 387.321 387.437 182.070 1.00 119.15 ? 351 PHE D CZ    1 
ATOM   12763 N  N     . LYS D 2 352 ? 390.388 380.876 181.460 1.00 120.28 ? 352 LYS D N     1 
ATOM   12764 C  CA    . LYS D 2 352 ? 390.496 379.482 181.055 1.00 120.42 ? 352 LYS D CA    1 
ATOM   12765 C  C     . LYS D 2 352 ? 389.118 378.863 181.228 1.00 122.73 ? 352 LYS D C     1 
ATOM   12766 O  O     . LYS D 2 352 ? 388.462 379.097 182.247 1.00 124.16 ? 352 LYS D O     1 
ATOM   12767 C  CB    . LYS D 2 352 ? 391.546 378.747 181.900 1.00 120.24 ? 352 LYS D CB    1 
ATOM   12768 C  CG    . LYS D 2 352 ? 391.652 377.231 181.693 1.00 116.81 ? 352 LYS D CG    1 
ATOM   12769 C  CD    . LYS D 2 352 ? 391.963 376.855 180.255 1.00 114.98 ? 352 LYS D CD    1 
ATOM   12770 C  CE    . LYS D 2 352 ? 392.184 375.359 180.121 1.00 116.64 ? 352 LYS D CE    1 
ATOM   12771 N  NZ    . LYS D 2 352 ? 392.307 374.931 178.702 1.00 123.94 ? 352 LYS D NZ    1 
ATOM   12772 N  N     . VAL D 2 353 ? 388.676 378.100 180.230 1.00 113.50 ? 353 VAL D N     1 
ATOM   12773 C  CA    . VAL D 2 353 ? 387.336 377.526 180.191 1.00 108.72 ? 353 VAL D CA    1 
ATOM   12774 C  C     . VAL D 2 353 ? 387.458 376.012 180.129 1.00 113.54 ? 353 VAL D C     1 
ATOM   12775 O  O     . VAL D 2 353 ? 388.253 375.476 179.349 1.00 115.06 ? 353 VAL D O     1 
ATOM   12776 C  CB    . VAL D 2 353 ? 386.526 378.057 178.989 1.00 108.57 ? 353 VAL D CB    1 
ATOM   12777 C  CG1   . VAL D 2 353 ? 385.049 377.673 179.118 1.00 109.21 ? 353 VAL D CG1   1 
ATOM   12778 C  CG2   . VAL D 2 353 ? 386.688 379.569 178.864 1.00 111.71 ? 353 VAL D CG2   1 
ATOM   12779 N  N     . GLY D 2 354 ? 386.679 375.331 180.966 1.00 119.96 ? 354 GLY D N     1 
ATOM   12780 C  CA    . GLY D 2 354 ? 386.504 373.895 180.877 1.00 115.84 ? 354 GLY D CA    1 
ATOM   12781 C  C     . GLY D 2 354 ? 385.035 373.560 180.988 1.00 114.20 ? 354 GLY D C     1 
ATOM   12782 O  O     . GLY D 2 354 ? 384.331 374.179 181.787 1.00 117.28 ? 354 GLY D O     1 
ATOM   12783 N  N     . ILE D 2 355 ? 384.555 372.621 180.173 1.00 103.86 ? 355 ILE D N     1 
ATOM   12784 C  CA    . ILE D 2 355 ? 383.153 372.214 180.144 1.00 103.87 ? 355 ILE D CA    1 
ATOM   12785 C  C     . ILE D 2 355 ? 383.102 370.698 180.236 1.00 105.19 ? 355 ILE D C     1 
ATOM   12786 O  O     . ILE D 2 355 ? 383.950 370.007 179.659 1.00 109.09 ? 355 ILE D O     1 
ATOM   12787 C  CB    . ILE D 2 355 ? 382.425 372.696 178.866 1.00 100.37 ? 355 ILE D CB    1 
ATOM   12788 C  CG1   . ILE D 2 355 ? 382.383 374.227 178.769 1.00 102.71 ? 355 ILE D CG1   1 
ATOM   12789 C  CG2   . ILE D 2 355 ? 381.000 372.148 178.812 1.00 101.98 ? 355 ILE D CG2   1 
ATOM   12790 C  CD1   . ILE D 2 355 ? 382.300 374.732 177.346 1.00 104.94 ? 355 ILE D CD1   1 
ATOM   12791 N  N     . ASN D 2 356 ? 382.121 370.179 180.973 1.00 103.02 ? 356 ASN D N     1 
ATOM   12792 C  CA    . ASN D 2 356 ? 381.826 368.752 180.903 1.00 100.58 ? 356 ASN D CA    1 
ATOM   12793 C  C     . ASN D 2 356 ? 380.331 368.519 181.080 1.00 106.88 ? 356 ASN D C     1 
ATOM   12794 O  O     . ASN D 2 356 ? 379.586 369.396 181.524 1.00 111.16 ? 356 ASN D O     1 
ATOM   12795 C  CB    . ASN D 2 356 ? 382.634 367.948 181.926 1.00 93.07  ? 356 ASN D CB    1 
ATOM   12796 C  CG    . ASN D 2 356 ? 382.205 368.214 183.339 1.00 101.44 ? 356 ASN D CG    1 
ATOM   12797 O  OD1   . ASN D 2 356 ? 381.924 369.350 183.704 1.00 110.86 ? 356 ASN D OD1   1 
ATOM   12798 N  ND2   . ASN D 2 356 ? 382.137 367.164 184.146 1.00 102.13 ? 356 ASN D ND2   1 
ATOM   12799 N  N     . TYR D 2 357 ? 379.898 367.319 180.696 1.00 104.60 ? 357 TYR D N     1 
ATOM   12800 C  CA    . TYR D 2 357 ? 378.475 367.033 180.571 1.00 106.00 ? 357 TYR D CA    1 
ATOM   12801 C  C     . TYR D 2 357 ? 377.814 366.637 181.884 1.00 105.11 ? 357 TYR D C     1 
ATOM   12802 O  O     . TYR D 2 357 ? 376.612 366.870 182.044 1.00 100.47 ? 357 TYR D O     1 
ATOM   12803 C  CB    . TYR D 2 357 ? 378.263 365.923 179.540 1.00 106.27 ? 357 TYR D CB    1 
ATOM   12804 C  CG    . TYR D 2 357 ? 378.953 366.183 178.220 1.00 104.11 ? 357 TYR D CG    1 
ATOM   12805 C  CD1   . TYR D 2 357 ? 378.626 367.291 177.451 1.00 102.62 ? 357 TYR D CD1   1 
ATOM   12806 C  CD2   . TYR D 2 357 ? 379.933 365.324 177.747 1.00 107.66 ? 357 TYR D CD2   1 
ATOM   12807 C  CE1   . TYR D 2 357 ? 379.254 367.533 176.245 1.00 108.60 ? 357 TYR D CE1   1 
ATOM   12808 C  CE2   . TYR D 2 357 ? 380.567 365.558 176.542 1.00 113.26 ? 357 TYR D CE2   1 
ATOM   12809 C  CZ    . TYR D 2 357 ? 380.223 366.664 175.796 1.00 114.83 ? 357 TYR D CZ    1 
ATOM   12810 O  OH    . TYR D 2 357 ? 380.853 366.900 174.596 1.00 116.98 ? 357 TYR D OH    1 
ATOM   12811 N  N     . GLN D 2 358 ? 378.552 366.057 182.820 1.00 105.99 ? 358 GLN D N     1 
ATOM   12812 C  CA    . GLN D 2 358 ? 377.938 365.519 184.031 1.00 105.13 ? 358 GLN D CA    1 
ATOM   12813 C  C     . GLN D 2 358 ? 377.485 366.658 184.946 1.00 99.27  ? 358 GLN D C     1 
ATOM   12814 O  O     . GLN D 2 358 ? 378.336 367.431 185.398 1.00 101.01 ? 358 GLN D O     1 
ATOM   12815 C  CB    . GLN D 2 358 ? 378.941 364.626 184.761 1.00 112.10 ? 358 GLN D CB    1 
ATOM   12816 C  CG    . GLN D 2 358 ? 378.374 363.824 185.936 1.00 109.33 ? 358 GLN D CG    1 
ATOM   12817 C  CD    . GLN D 2 358 ? 377.384 362.760 185.508 1.00 115.27 ? 358 GLN D CD    1 
ATOM   12818 O  OE1   . GLN D 2 358 ? 377.334 362.373 184.340 1.00 116.24 ? 358 GLN D OE1   1 
ATOM   12819 N  NE2   . GLN D 2 358 ? 376.584 362.283 186.454 1.00 114.46 ? 358 GLN D NE2   1 
ATOM   12820 N  N     . PRO D 2 359 ? 376.196 366.798 185.272 1.00 106.02 ? 359 PRO D N     1 
ATOM   12821 C  CA    . PRO D 2 359 ? 375.809 367.811 186.264 1.00 111.63 ? 359 PRO D CA    1 
ATOM   12822 C  C     . PRO D 2 359 ? 376.175 367.358 187.665 1.00 110.60 ? 359 PRO D C     1 
ATOM   12823 O  O     . PRO D 2 359 ? 376.508 366.182 187.872 1.00 105.87 ? 359 PRO D O     1 
ATOM   12824 C  CB    . PRO D 2 359 ? 374.287 367.917 186.089 1.00 111.71 ? 359 PRO D CB    1 
ATOM   12825 C  CG    . PRO D 2 359 ? 373.887 366.606 185.589 1.00 114.60 ? 359 PRO D CG    1 
ATOM   12826 C  CD    . PRO D 2 359 ? 374.996 366.156 184.696 1.00 111.47 ? 359 PRO D CD    1 
ATOM   12827 N  N     . PRO D 2 360 ? 376.135 368.249 188.655 1.00 117.47 ? 360 PRO D N     1 
ATOM   12828 C  CA    . PRO D 2 360 ? 376.448 367.828 190.023 1.00 116.70 ? 360 PRO D CA    1 
ATOM   12829 C  C     . PRO D 2 360 ? 375.336 366.970 190.603 1.00 122.50 ? 360 PRO D C     1 
ATOM   12830 O  O     . PRO D 2 360 ? 374.182 367.026 190.175 1.00 128.00 ? 360 PRO D O     1 
ATOM   12831 C  CB    . PRO D 2 360 ? 376.575 369.152 190.779 1.00 113.48 ? 360 PRO D CB    1 
ATOM   12832 C  CG    . PRO D 2 360 ? 375.651 370.053 190.062 1.00 116.11 ? 360 PRO D CG    1 
ATOM   12833 C  CD    . PRO D 2 360 ? 375.750 369.672 188.610 1.00 116.88 ? 360 PRO D CD    1 
ATOM   12834 N  N     . THR D 2 361 ? 375.710 366.167 191.598 1.00 123.46 ? 361 THR D N     1 
ATOM   12835 C  CA    . THR D 2 361 ? 374.784 365.314 192.337 1.00 125.88 ? 361 THR D CA    1 
ATOM   12836 C  C     . THR D 2 361 ? 374.601 365.902 193.726 1.00 128.00 ? 361 THR D C     1 
ATOM   12837 O  O     . THR D 2 361 ? 375.585 366.141 194.434 1.00 129.41 ? 361 THR D O     1 
ATOM   12838 C  CB    . THR D 2 361 ? 375.309 363.885 192.453 1.00 121.60 ? 361 THR D CB    1 
ATOM   12839 O  OG1   . THR D 2 361 ? 376.589 363.901 193.093 1.00 119.00 ? 361 THR D OG1   1 
ATOM   12840 C  CG2   . THR D 2 361 ? 375.433 363.247 191.074 1.00 122.74 ? 361 THR D CG2   1 
ATOM   12841 N  N     . VAL D 2 362 ? 373.353 366.128 194.115 1.00 129.71 ? 362 VAL D N     1 
ATOM   12842 C  CA    . VAL D 2 362 ? 373.051 366.593 195.463 1.00 128.80 ? 362 VAL D CA    1 
ATOM   12843 C  C     . VAL D 2 362 ? 373.082 365.405 196.414 1.00 131.16 ? 362 VAL D C     1 
ATOM   12844 O  O     . VAL D 2 362 ? 372.536 364.334 196.121 1.00 129.95 ? 362 VAL D O     1 
ATOM   12845 C  CB    . VAL D 2 362 ? 371.698 367.331 195.494 1.00 124.36 ? 362 VAL D CB    1 
ATOM   12846 C  CG1   . VAL D 2 362 ? 371.639 368.367 194.383 1.00 128.51 ? 362 VAL D CG1   1 
ATOM   12847 C  CG2   . VAL D 2 362 ? 370.524 366.365 195.363 1.00 122.07 ? 362 VAL D CG2   1 
ATOM   12848 N  N     . VAL D 2 363 ? 373.763 365.574 197.542 1.00 135.00 ? 363 VAL D N     1 
ATOM   12849 C  CA    . VAL D 2 363 ? 373.837 364.521 198.552 1.00 136.35 ? 363 VAL D CA    1 
ATOM   12850 C  C     . VAL D 2 363 ? 372.465 364.429 199.215 1.00 139.03 ? 363 VAL D C     1 
ATOM   12851 O  O     . VAL D 2 363 ? 371.725 365.424 199.204 1.00 134.46 ? 363 VAL D O     1 
ATOM   12852 C  CB    . VAL D 2 363 ? 374.943 364.794 199.586 1.00 132.42 ? 363 VAL D CB    1 
ATOM   12853 C  CG1   . VAL D 2 363 ? 376.290 364.955 198.897 1.00 128.02 ? 363 VAL D CG1   1 
ATOM   12854 C  CG2   . VAL D 2 363 ? 374.613 366.017 200.448 1.00 134.97 ? 363 VAL D CG2   1 
ATOM   12855 N  N     . PRO D 2 364 ? 372.064 363.287 199.781 1.00 152.91 ? 364 PRO D N     1 
ATOM   12856 C  CA    . PRO D 2 364 ? 370.809 363.268 200.543 1.00 151.19 ? 364 PRO D CA    1 
ATOM   12857 C  C     . PRO D 2 364 ? 370.905 364.152 201.777 1.00 152.29 ? 364 PRO D C     1 
ATOM   12858 O  O     . PRO D 2 364 ? 371.937 364.204 202.449 1.00 151.19 ? 364 PRO D O     1 
ATOM   12859 C  CB    . PRO D 2 364 ? 370.635 361.791 200.917 1.00 150.20 ? 364 PRO D CB    1 
ATOM   12860 C  CG    . PRO D 2 364 ? 371.503 361.043 199.980 1.00 150.24 ? 364 PRO D CG    1 
ATOM   12861 C  CD    . PRO D 2 364 ? 372.660 361.941 199.704 1.00 148.00 ? 364 PRO D CD    1 
ATOM   12862 N  N     . GLY D 2 365 ? 369.813 364.853 202.070 1.00 161.97 ? 365 GLY D N     1 
ATOM   12863 C  CA    . GLY D 2 365 ? 369.779 365.731 203.222 1.00 160.59 ? 365 GLY D CA    1 
ATOM   12864 C  C     . GLY D 2 365 ? 370.580 367.005 203.085 1.00 159.26 ? 365 GLY D C     1 
ATOM   12865 O  O     . GLY D 2 365 ? 370.761 367.711 204.083 1.00 157.45 ? 365 GLY D O     1 
ATOM   12866 N  N     . GLY D 2 366 ? 371.067 367.329 201.884 1.00 151.67 ? 366 GLY D N     1 
ATOM   12867 C  CA    . GLY D 2 366 ? 371.834 368.539 201.689 1.00 149.65 ? 366 GLY D CA    1 
ATOM   12868 C  C     . GLY D 2 366 ? 370.957 369.765 201.538 1.00 151.43 ? 366 GLY D C     1 
ATOM   12869 O  O     . GLY D 2 366 ? 369.742 369.681 201.356 1.00 153.83 ? 366 GLY D O     1 
ATOM   12870 N  N     . ASP D 2 367 ? 371.609 370.926 201.618 1.00 145.38 ? 367 ASP D N     1 
ATOM   12871 C  CA    . ASP D 2 367 ? 370.948 372.216 201.466 1.00 144.38 ? 367 ASP D CA    1 
ATOM   12872 C  C     . ASP D 2 367 ? 371.024 372.759 200.047 1.00 140.47 ? 367 ASP D C     1 
ATOM   12873 O  O     . ASP D 2 367 ? 370.189 373.591 199.673 1.00 136.67 ? 367 ASP D O     1 
ATOM   12874 C  CB    . ASP D 2 367 ? 371.573 373.230 202.423 1.00 145.19 ? 367 ASP D CB    1 
ATOM   12875 C  CG    . ASP D 2 367 ? 371.219 372.953 203.863 1.00 147.12 ? 367 ASP D CG    1 
ATOM   12876 O  OD1   . ASP D 2 367 ? 370.280 372.170 204.112 1.00 144.83 ? 367 ASP D OD1   1 
ATOM   12877 O  OD2   . ASP D 2 367 ? 371.901 373.501 204.749 1.00 149.50 ? 367 ASP D OD2   1 
ATOM   12878 N  N     . LEU D 2 368 ? 372.000 372.320 199.258 1.00 142.73 ? 368 LEU D N     1 
ATOM   12879 C  CA    . LEU D 2 368 ? 372.102 372.765 197.875 1.00 144.82 ? 368 LEU D CA    1 
ATOM   12880 C  C     . LEU D 2 368 ? 370.914 372.267 197.065 1.00 146.08 ? 368 LEU D C     1 
ATOM   12881 O  O     . LEU D 2 368 ? 370.477 371.121 197.206 1.00 145.91 ? 368 LEU D O     1 
ATOM   12882 C  CB    . LEU D 2 368 ? 373.406 372.261 197.242 1.00 144.11 ? 368 LEU D CB    1 
ATOM   12883 C  CG    . LEU D 2 368 ? 374.643 373.167 197.186 1.00 142.55 ? 368 LEU D CG    1 
ATOM   12884 C  CD1   . LEU D 2 368 ? 374.368 374.515 196.524 1.00 141.14 ? 368 LEU D CD1   1 
ATOM   12885 C  CD2   . LEU D 2 368 ? 375.180 373.369 198.595 1.00 143.99 ? 368 LEU D CD2   1 
ATOM   12886 N  N     . ALA D 2 369 ? 370.392 373.143 196.214 1.00 152.62 ? 369 ALA D N     1 
ATOM   12887 C  CA    . ALA D 2 369 ? 369.292 372.789 195.334 1.00 149.88 ? 369 ALA D CA    1 
ATOM   12888 C  C     . ALA D 2 369 ? 369.806 372.006 194.134 1.00 148.49 ? 369 ALA D C     1 
ATOM   12889 O  O     . ALA D 2 369 ? 370.934 372.201 193.674 1.00 149.02 ? 369 ALA D O     1 
ATOM   12890 C  CB    . ALA D 2 369 ? 368.564 374.045 194.861 1.00 147.66 ? 369 ALA D CB    1 
ATOM   12891 N  N     . LYS D 2 370 ? 368.965 371.108 193.630 1.00 146.09 ? 370 LYS D N     1 
ATOM   12892 C  CA    . LYS D 2 370 ? 369.300 370.382 192.414 1.00 148.07 ? 370 LYS D CA    1 
ATOM   12893 C  C     . LYS D 2 370 ? 369.267 371.341 191.231 1.00 148.54 ? 370 LYS D C     1 
ATOM   12894 O  O     . LYS D 2 370 ? 368.314 372.109 191.070 1.00 146.42 ? 370 LYS D O     1 
ATOM   12895 C  CB    . LYS D 2 370 ? 368.320 369.224 192.206 1.00 145.86 ? 370 LYS D CB    1 
ATOM   12896 C  CG    . LYS D 2 370 ? 368.541 368.365 190.951 1.00 146.18 ? 370 LYS D CG    1 
ATOM   12897 C  CD    . LYS D 2 370 ? 369.924 367.723 190.906 1.00 147.00 ? 370 LYS D CD    1 
ATOM   12898 C  CE    . LYS D 2 370 ? 370.065 366.789 189.715 1.00 145.54 ? 370 LYS D CE    1 
ATOM   12899 N  NZ    . LYS D 2 370 ? 371.368 366.070 189.723 1.00 145.62 ? 370 LYS D NZ    1 
ATOM   12900 N  N     . VAL D 2 371 ? 370.314 371.299 190.409 1.00 143.04 ? 371 VAL D N     1 
ATOM   12901 C  CA    . VAL D 2 371 ? 370.467 372.197 189.269 1.00 137.82 ? 371 VAL D CA    1 
ATOM   12902 C  C     . VAL D 2 371 ? 371.083 371.424 188.114 1.00 141.46 ? 371 VAL D C     1 
ATOM   12903 O  O     . VAL D 2 371 ? 371.982 370.600 188.311 1.00 141.73 ? 371 VAL D O     1 
ATOM   12904 C  CB    . VAL D 2 371 ? 371.322 373.435 189.623 1.00 136.23 ? 371 VAL D CB    1 
ATOM   12905 C  CG1   . VAL D 2 371 ? 370.546 374.370 190.537 1.00 138.15 ? 371 VAL D CG1   1 
ATOM   12906 C  CG2   . VAL D 2 371 ? 372.655 373.037 190.281 1.00 136.32 ? 371 VAL D CG2   1 
ATOM   12907 N  N     . GLN D 2 372 ? 370.594 371.693 186.903 1.00 129.33 ? 372 GLN D N     1 
ATOM   12908 C  CA    . GLN D 2 372 ? 371.155 371.086 185.702 1.00 130.79 ? 372 GLN D CA    1 
ATOM   12909 C  C     . GLN D 2 372 ? 372.450 371.748 185.239 1.00 131.53 ? 372 GLN D C     1 
ATOM   12910 O  O     . GLN D 2 372 ? 373.109 371.202 184.348 1.00 130.59 ? 372 GLN D O     1 
ATOM   12911 C  CB    . GLN D 2 372 ? 370.128 371.113 184.559 1.00 130.16 ? 372 GLN D CB    1 
ATOM   12912 C  CG    . GLN D 2 372 ? 369.578 372.490 184.183 1.00 130.95 ? 372 GLN D CG    1 
ATOM   12913 C  CD    . GLN D 2 372 ? 368.202 372.741 184.766 1.00 132.51 ? 372 GLN D CD    1 
ATOM   12914 O  OE1   . GLN D 2 372 ? 368.059 372.979 185.965 1.00 129.24 ? 372 GLN D OE1   1 
ATOM   12915 N  NE2   . GLN D 2 372 ? 367.179 372.685 183.920 1.00 133.18 ? 372 GLN D NE2   1 
ATOM   12916 N  N     . ARG D 2 373 ? 372.820 372.900 185.807 1.00 131.90 ? 373 ARG D N     1 
ATOM   12917 C  CA    . ARG D 2 373 ? 374.046 373.614 185.475 1.00 124.93 ? 373 ARG D CA    1 
ATOM   12918 C  C     . ARG D 2 373 ? 374.792 373.954 186.753 1.00 125.34 ? 373 ARG D C     1 
ATOM   12919 O  O     . ARG D 2 373 ? 374.175 374.243 187.782 1.00 129.15 ? 373 ARG D O     1 
ATOM   12920 C  CB    . ARG D 2 373 ? 373.748 374.905 184.710 1.00 122.91 ? 373 ARG D CB    1 
ATOM   12921 C  CG    . ARG D 2 373 ? 373.340 374.696 183.270 1.00 127.10 ? 373 ARG D CG    1 
ATOM   12922 C  CD    . ARG D 2 373 ? 372.967 376.012 182.607 1.00 127.37 ? 373 ARG D CD    1 
ATOM   12923 N  NE    . ARG D 2 373 ? 371.707 376.543 183.116 1.00 130.61 ? 373 ARG D NE    1 
ATOM   12924 C  CZ    . ARG D 2 373 ? 370.496 376.110 182.780 1.00 130.74 ? 373 ARG D CZ    1 
ATOM   12925 N  NH1   . ARG D 2 373 ? 370.319 375.117 181.918 1.00 128.46 ? 373 ARG D NH1   1 
ATOM   12926 N  NH2   . ARG D 2 373 ? 369.430 376.687 183.324 1.00 130.32 ? 373 ARG D NH2   1 
ATOM   12927 N  N     . ALA D 2 374 ? 376.120 373.918 186.685 1.00 111.14 ? 374 ALA D N     1 
ATOM   12928 C  CA    . ALA D 2 374 ? 376.938 374.397 187.789 1.00 111.93 ? 374 ALA D CA    1 
ATOM   12929 C  C     . ALA D 2 374 ? 378.260 374.890 187.230 1.00 113.29 ? 374 ALA D C     1 
ATOM   12930 O  O     . ALA D 2 374 ? 378.660 374.507 186.129 1.00 117.07 ? 374 ALA D O     1 
ATOM   12931 C  CB    . ALA D 2 374 ? 377.165 373.308 188.840 1.00 117.31 ? 374 ALA D CB    1 
ATOM   12932 N  N     . VAL D 2 375 ? 378.925 375.752 187.996 1.00 109.38 ? 375 VAL D N     1 
ATOM   12933 C  CA    . VAL D 2 375 ? 380.199 376.339 187.603 1.00 104.72 ? 375 VAL D CA    1 
ATOM   12934 C  C     . VAL D 2 375 ? 381.069 376.484 188.842 1.00 107.24 ? 375 VAL D C     1 
ATOM   12935 O  O     . VAL D 2 375 ? 380.581 376.843 189.920 1.00 112.95 ? 375 VAL D O     1 
ATOM   12936 C  CB    . VAL D 2 375 ? 380.005 377.694 186.884 1.00 105.23 ? 375 VAL D CB    1 
ATOM   12937 C  CG1   . VAL D 2 375 ? 379.135 378.649 187.698 1.00 110.48 ? 375 VAL D CG1   1 
ATOM   12938 C  CG2   . VAL D 2 375 ? 381.351 378.331 186.569 1.00 105.08 ? 375 VAL D CG2   1 
ATOM   12939 N  N     . CYS D 2 376 ? 382.356 376.179 188.686 1.00 113.34 ? 376 CYS D N     1 
ATOM   12940 C  CA    . CYS D 2 376 ? 383.359 376.342 189.737 1.00 112.61 ? 376 CYS D CA    1 
ATOM   12941 C  C     . CYS D 2 376 ? 384.419 377.306 189.221 1.00 106.65 ? 376 CYS D C     1 
ATOM   12942 O  O     . CYS D 2 376 ? 385.049 377.045 188.191 1.00 107.18 ? 376 CYS D O     1 
ATOM   12943 C  CB    . CYS D 2 376 ? 383.962 374.993 190.122 1.00 113.39 ? 376 CYS D CB    1 
ATOM   12944 S  SG    . CYS D 2 376 ? 385.408 375.088 191.186 1.00 127.82 ? 376 CYS D SG    1 
ATOM   12945 N  N     . MET D 2 377 ? 384.598 378.422 189.930 1.00 106.72 ? 377 MET D N     1 
ATOM   12946 C  CA    . MET D 2 377 ? 385.476 379.510 189.513 1.00 106.97 ? 377 MET D CA    1 
ATOM   12947 C  C     . MET D 2 377 ? 386.682 379.568 190.443 1.00 108.50 ? 377 MET D C     1 
ATOM   12948 O  O     . MET D 2 377 ? 386.524 379.671 191.664 1.00 112.97 ? 377 MET D O     1 
ATOM   12949 C  CB    . MET D 2 377 ? 384.719 380.840 189.523 1.00 117.12 ? 377 MET D CB    1 
ATOM   12950 C  CG    . MET D 2 377 ? 385.557 382.062 189.160 1.00 118.36 ? 377 MET D CG    1 
ATOM   12951 S  SD    . MET D 2 377 ? 385.973 383.095 190.573 1.00 133.93 ? 377 MET D SD    1 
ATOM   12952 C  CE    . MET D 2 377 ? 386.018 384.704 189.791 1.00 118.80 ? 377 MET D CE    1 
ATOM   12953 N  N     . LEU D 2 378 ? 387.879 379.504 189.858 1.00 100.40 ? 378 LEU D N     1 
ATOM   12954 C  CA    . LEU D 2 378 ? 389.148 379.592 190.568 1.00 102.60 ? 378 LEU D CA    1 
ATOM   12955 C  C     . LEU D 2 378 ? 389.896 380.804 190.039 1.00 105.94 ? 378 LEU D C     1 
ATOM   12956 O  O     . LEU D 2 378 ? 390.196 380.869 188.843 1.00 112.31 ? 378 LEU D O     1 
ATOM   12957 C  CB    . LEU D 2 378 ? 389.985 378.326 190.358 1.00 102.72 ? 378 LEU D CB    1 
ATOM   12958 C  CG    . LEU D 2 378 ? 389.488 376.983 190.901 1.00 106.81 ? 378 LEU D CG    1 
ATOM   12959 C  CD1   . LEU D 2 378 ? 390.365 375.824 190.478 1.00 114.99 ? 378 LEU D CD1   1 
ATOM   12960 C  CD2   . LEU D 2 378 ? 389.421 377.047 192.417 1.00 106.18 ? 378 LEU D CD2   1 
ATOM   12961 N  N     . SER D 2 379 ? 390.216 381.746 190.926 1.00 111.09 ? 379 SER D N     1 
ATOM   12962 C  CA    . SER D 2 379 ? 390.745 383.048 190.527 1.00 116.27 ? 379 SER D CA    1 
ATOM   12963 C  C     . SER D 2 379 ? 392.015 383.355 191.302 1.00 116.41 ? 379 SER D C     1 
ATOM   12964 O  O     . SER D 2 379 ? 391.984 383.480 192.529 1.00 116.73 ? 379 SER D O     1 
ATOM   12965 C  CB    . SER D 2 379 ? 389.704 384.147 190.755 1.00 118.58 ? 379 SER D CB    1 
ATOM   12966 O  OG    . SER D 2 379 ? 389.160 384.070 192.059 1.00 124.38 ? 379 SER D OG    1 
ATOM   12967 N  N     . ASN D 2 380 ? 393.122 383.479 190.574 1.00 105.16 ? 380 ASN D N     1 
ATOM   12968 C  CA    . ASN D 2 380 ? 394.361 384.046 191.085 1.00 103.24 ? 380 ASN D CA    1 
ATOM   12969 C  C     . ASN D 2 380 ? 394.305 385.555 190.895 1.00 103.51 ? 380 ASN D C     1 
ATOM   12970 O  O     . ASN D 2 380 ? 394.216 386.040 189.757 1.00 104.22 ? 380 ASN D O     1 
ATOM   12971 C  CB    . ASN D 2 380 ? 395.566 383.454 190.357 1.00 104.79 ? 380 ASN D CB    1 
ATOM   12972 C  CG    . ASN D 2 380 ? 396.853 383.591 191.145 1.00 105.92 ? 380 ASN D CG    1 
ATOM   12973 O  OD1   . ASN D 2 380 ? 396.924 384.338 192.120 1.00 113.26 ? 380 ASN D OD1   1 
ATOM   12974 N  ND2   . ASN D 2 380 ? 397.883 382.871 190.720 1.00 102.16 ? 380 ASN D ND2   1 
ATOM   12975 N  N     . THR D 2 381 ? 394.355 386.281 192.012 1.00 106.03 ? 381 THR D N     1 
ATOM   12976 C  CA    . THR D 2 381 ? 394.170 387.723 192.050 1.00 107.22 ? 381 THR D CA    1 
ATOM   12977 C  C     . THR D 2 381 ? 394.998 388.294 193.192 1.00 106.65 ? 381 THR D C     1 
ATOM   12978 O  O     . THR D 2 381 ? 395.446 387.568 194.083 1.00 110.23 ? 381 THR D O     1 
ATOM   12979 C  CB    . THR D 2 381 ? 392.692 388.103 192.223 1.00 105.81 ? 381 THR D CB    1 
ATOM   12980 O  OG1   . THR D 2 381 ? 392.550 389.526 192.140 1.00 105.71 ? 381 THR D OG1   1 
ATOM   12981 C  CG2   . THR D 2 381 ? 392.134 387.619 193.567 1.00 98.55  ? 381 THR D CG2   1 
ATOM   12982 N  N     . THR D 2 382 ? 395.191 389.612 193.159 1.00 103.35 ? 382 THR D N     1 
ATOM   12983 C  CA    . THR D 2 382 ? 396.033 390.297 194.133 1.00 104.24 ? 382 THR D CA    1 
ATOM   12984 C  C     . THR D 2 382 ? 395.322 390.619 195.443 1.00 106.83 ? 382 THR D C     1 
ATOM   12985 O  O     . THR D 2 382 ? 395.964 391.163 196.348 1.00 108.25 ? 382 THR D O     1 
ATOM   12986 C  CB    . THR D 2 382 ? 396.577 391.597 193.534 1.00 103.94 ? 382 THR D CB    1 
ATOM   12987 O  OG1   . THR D 2 382 ? 395.487 392.433 193.127 1.00 105.73 ? 382 THR D OG1   1 
ATOM   12988 C  CG2   . THR D 2 382 ? 397.463 391.308 192.337 1.00 101.88 ? 382 THR D CG2   1 
ATOM   12989 N  N     . ALA D 2 383 ? 394.029 390.312 195.576 1.00 110.24 ? 383 ALA D N     1 
ATOM   12990 C  CA    . ALA D 2 383 ? 393.305 390.635 196.801 1.00 113.67 ? 383 ALA D CA    1 
ATOM   12991 C  C     . ALA D 2 383 ? 393.836 389.882 198.015 1.00 115.67 ? 383 ALA D C     1 
ATOM   12992 O  O     . ALA D 2 383 ? 393.686 390.367 199.141 1.00 115.72 ? 383 ALA D O     1 
ATOM   12993 C  CB    . ALA D 2 383 ? 391.818 390.337 196.621 1.00 114.81 ? 383 ALA D CB    1 
ATOM   12994 N  N     . ILE D 2 384 ? 394.455 388.716 197.816 1.00 109.36 ? 384 ILE D N     1 
ATOM   12995 C  CA    . ILE D 2 384 ? 395.059 387.967 198.915 1.00 109.58 ? 384 ILE D CA    1 
ATOM   12996 C  C     . ILE D 2 384 ? 396.278 388.674 199.502 1.00 113.75 ? 384 ILE D C     1 
ATOM   12997 O  O     . ILE D 2 384 ? 396.716 388.327 200.609 1.00 118.95 ? 384 ILE D O     1 
ATOM   12998 C  CB    . ILE D 2 384 ? 395.374 386.543 198.396 1.00 105.84 ? 384 ILE D CB    1 
ATOM   12999 C  CG1   . ILE D 2 384 ? 395.645 385.551 199.539 1.00 111.90 ? 384 ILE D CG1   1 
ATOM   13000 C  CG2   . ILE D 2 384 ? 396.531 386.547 197.382 1.00 105.73 ? 384 ILE D CG2   1 
ATOM   13001 C  CD1   . ILE D 2 384 ? 394.431 384.741 199.939 1.00 111.09 ? 384 ILE D CD1   1 
ATOM   13002 N  N     . ALA D 2 385 ? 396.843 389.656 198.792 1.00 102.50 ? 385 ALA D N     1 
ATOM   13003 C  CA    . ALA D 2 385 ? 397.921 390.458 199.359 1.00 103.23 ? 385 ALA D CA    1 
ATOM   13004 C  C     . ALA D 2 385 ? 397.459 391.194 200.609 1.00 107.33 ? 385 ALA D C     1 
ATOM   13005 O  O     . ALA D 2 385 ? 398.216 391.322 201.576 1.00 108.58 ? 385 ALA D O     1 
ATOM   13006 C  CB    . ALA D 2 385 ? 398.440 391.447 198.317 1.00 102.21 ? 385 ALA D CB    1 
ATOM   13007 N  N     . GLU D 2 386 ? 396.213 391.675 200.612 1.00 117.59 ? 386 GLU D N     1 
ATOM   13008 C  CA    . GLU D 2 386 ? 395.663 392.308 201.808 1.00 117.86 ? 386 GLU D CA    1 
ATOM   13009 C  C     . GLU D 2 386 ? 395.580 391.319 202.963 1.00 117.25 ? 386 GLU D C     1 
ATOM   13010 O  O     . GLU D 2 386 ? 395.895 391.660 204.112 1.00 122.89 ? 386 GLU D O     1 
ATOM   13011 C  CB    . GLU D 2 386 ? 394.276 392.881 201.510 1.00 119.25 ? 386 GLU D CB    1 
ATOM   13012 C  CG    . GLU D 2 386 ? 394.226 393.908 200.383 1.00 123.44 ? 386 GLU D CG    1 
ATOM   13013 C  CD    . GLU D 2 386 ? 394.995 395.175 200.703 1.00 129.74 ? 386 GLU D CD    1 
ATOM   13014 O  OE1   . GLU D 2 386 ? 395.217 395.453 201.900 1.00 133.15 ? 386 GLU D OE1   1 
ATOM   13015 O  OE2   . GLU D 2 386 ? 395.378 395.892 199.756 1.00 129.87 ? 386 GLU D OE2   1 
ATOM   13016 N  N     . ALA D 2 387 ? 395.152 390.089 202.676 1.00 102.66 ? 387 ALA D N     1 
ATOM   13017 C  CA    . ALA D 2 387 ? 395.030 389.088 203.727 1.00 105.44 ? 387 ALA D CA    1 
ATOM   13018 C  C     . ALA D 2 387 ? 396.387 388.737 204.315 1.00 104.73 ? 387 ALA D C     1 
ATOM   13019 O  O     . ALA D 2 387 ? 396.529 388.605 205.537 1.00 108.87 ? 387 ALA D O     1 
ATOM   13020 C  CB    . ALA D 2 387 ? 394.342 387.839 203.184 1.00 102.41 ? 387 ALA D CB    1 
ATOM   13021 N  N     . TRP D 2 388 ? 397.401 388.593 203.463 1.00 104.73 ? 388 TRP D N     1 
ATOM   13022 C  CA    . TRP D 2 388 ? 398.737 388.323 203.981 1.00 104.28 ? 388 TRP D CA    1 
ATOM   13023 C  C     . TRP D 2 388 ? 399.328 389.537 204.677 1.00 108.91 ? 388 TRP D C     1 
ATOM   13024 O  O     . TRP D 2 388 ? 400.155 389.378 205.574 1.00 117.36 ? 388 TRP D O     1 
ATOM   13025 C  CB    . TRP D 2 388 ? 399.668 387.856 202.862 1.00 104.40 ? 388 TRP D CB    1 
ATOM   13026 C  CG    . TRP D 2 388 ? 399.667 386.369 202.598 1.00 113.43 ? 388 TRP D CG    1 
ATOM   13027 C  CD1   . TRP D 2 388 ? 399.690 385.346 203.514 1.00 116.85 ? 388 TRP D CD1   1 
ATOM   13028 C  CD2   . TRP D 2 388 ? 399.623 385.748 201.319 1.00 113.99 ? 388 TRP D CD2   1 
ATOM   13029 N  NE1   . TRP D 2 388 ? 399.668 384.136 202.875 1.00 109.26 ? 388 TRP D NE1   1 
ATOM   13030 C  CE2   . TRP D 2 388 ? 399.627 384.356 201.525 1.00 116.47 ? 388 TRP D CE2   1 
ATOM   13031 C  CE3   . TRP D 2 388 ? 399.582 386.235 200.014 1.00 110.99 ? 388 TRP D CE3   1 
ATOM   13032 C  CZ2   . TRP D 2 388 ? 399.594 383.455 200.476 1.00 118.60 ? 388 TRP D CZ2   1 
ATOM   13033 C  CZ3   . TRP D 2 388 ? 399.553 385.342 198.985 1.00 117.48 ? 388 TRP D CZ3   1 
ATOM   13034 C  CH2   . TRP D 2 388 ? 399.555 383.973 199.215 1.00 123.08 ? 388 TRP D CH2   1 
ATOM   13035 N  N     . ALA D 2 389 ? 398.919 390.748 204.299 1.00 101.08 ? 389 ALA D N     1 
ATOM   13036 C  CA    . ALA D 2 389 ? 399.328 391.919 205.067 1.00 99.98  ? 389 ALA D CA    1 
ATOM   13037 C  C     . ALA D 2 389 ? 398.760 391.862 206.478 1.00 103.72 ? 389 ALA D C     1 
ATOM   13038 O  O     . ALA D 2 389 ? 399.471 392.132 207.454 1.00 105.89 ? 389 ALA D O     1 
ATOM   13039 C  CB    . ALA D 2 389 ? 398.881 393.195 204.356 1.00 99.57  ? 389 ALA D CB    1 
ATOM   13040 N  N     . ARG D 2 390 ? 397.483 391.486 206.601 1.00 115.46 ? 390 ARG D N     1 
ATOM   13041 C  CA    . ARG D 2 390 ? 396.881 391.310 207.922 1.00 113.36 ? 390 ARG D CA    1 
ATOM   13042 C  C     . ARG D 2 390 ? 397.601 390.228 208.715 1.00 115.41 ? 390 ARG D C     1 
ATOM   13043 O  O     . ARG D 2 390 ? 397.891 390.400 209.907 1.00 120.69 ? 390 ARG D O     1 
ATOM   13044 C  CB    . ARG D 2 390 ? 395.408 390.934 207.786 1.00 114.23 ? 390 ARG D CB    1 
ATOM   13045 C  CG    . ARG D 2 390 ? 394.498 392.013 207.232 1.00 123.66 ? 390 ARG D CG    1 
ATOM   13046 C  CD    . ARG D 2 390 ? 393.005 391.691 207.422 1.00 121.71 ? 390 ARG D CD    1 
ATOM   13047 N  NE    . ARG D 2 390 ? 392.483 390.741 206.440 1.00 120.67 ? 390 ARG D NE    1 
ATOM   13048 C  CZ    . ARG D 2 390 ? 392.606 389.418 206.487 1.00 122.16 ? 390 ARG D CZ    1 
ATOM   13049 N  NH1   . ARG D 2 390 ? 393.137 388.795 207.529 1.00 119.72 ? 390 ARG D NH1   1 
ATOM   13050 N  NH2   . ARG D 2 390 ? 392.165 388.692 205.463 1.00 120.42 ? 390 ARG D NH2   1 
ATOM   13051 N  N     . LEU D 2 391 ? 397.890 389.102 208.066 1.00 106.18 ? 391 LEU D N     1 
ATOM   13052 C  CA    . LEU D 2 391 ? 398.516 387.981 208.756 1.00 103.49 ? 391 LEU D CA    1 
ATOM   13053 C  C     . LEU D 2 391 ? 399.942 388.322 209.174 1.00 104.04 ? 391 LEU D C     1 
ATOM   13054 O  O     . LEU D 2 391 ? 400.387 387.938 210.262 1.00 107.89 ? 391 LEU D O     1 
ATOM   13055 C  CB    . LEU D 2 391 ? 398.479 386.755 207.845 1.00 96.71  ? 391 LEU D CB    1 
ATOM   13056 C  CG    . LEU D 2 391 ? 398.646 385.349 208.417 1.00 96.59  ? 391 LEU D CG    1 
ATOM   13057 C  CD1   . LEU D 2 391 ? 397.544 385.016 209.413 1.00 102.10 ? 391 LEU D CD1   1 
ATOM   13058 C  CD2   . LEU D 2 391 ? 398.640 384.366 207.256 1.00 101.46 ? 391 LEU D CD2   1 
ATOM   13059 N  N     . ASP D 2 392 ? 400.666 389.059 208.330 1.00 105.33 ? 392 ASP D N     1 
ATOM   13060 C  CA    . ASP D 2 392 ? 402.003 389.513 208.685 1.00 106.98 ? 392 ASP D CA    1 
ATOM   13061 C  C     . ASP D 2 392 ? 401.959 390.501 209.840 1.00 112.23 ? 392 ASP D C     1 
ATOM   13062 O  O     . ASP D 2 392 ? 402.839 390.488 210.704 1.00 117.46 ? 392 ASP D O     1 
ATOM   13063 C  CB    . ASP D 2 392 ? 402.677 390.147 207.470 1.00 115.22 ? 392 ASP D CB    1 
ATOM   13064 C  CG    . ASP D 2 392 ? 403.261 389.120 206.524 1.00 121.64 ? 392 ASP D CG    1 
ATOM   13065 O  OD1   . ASP D 2 392 ? 404.026 388.248 206.985 1.00 124.71 ? 392 ASP D OD1   1 
ATOM   13066 O  OD2   . ASP D 2 392 ? 402.955 389.184 205.316 1.00 125.57 ? 392 ASP D OD2   1 
ATOM   13067 N  N     . HIS D 2 393 ? 400.953 391.379 209.862 1.00 108.46 ? 393 HIS D N     1 
ATOM   13068 C  CA    . HIS D 2 393 ? 400.804 392.294 210.990 1.00 108.51 ? 393 HIS D CA    1 
ATOM   13069 C  C     . HIS D 2 393 ? 400.541 391.533 212.283 1.00 109.42 ? 393 HIS D C     1 
ATOM   13070 O  O     . HIS D 2 393 ? 401.103 391.868 213.335 1.00 116.41 ? 393 HIS D O     1 
ATOM   13071 C  CB    . HIS D 2 393 ? 399.673 393.281 210.710 1.00 111.23 ? 393 HIS D CB    1 
ATOM   13072 C  CG    . HIS D 2 393 ? 399.561 394.374 211.725 1.00 114.77 ? 393 HIS D CG    1 
ATOM   13073 N  ND1   . HIS D 2 393 ? 398.452 394.532 212.527 1.00 117.63 ? 393 HIS D ND1   1 
ATOM   13074 C  CD2   . HIS D 2 393 ? 400.420 395.360 212.072 1.00 111.81 ? 393 HIS D CD2   1 
ATOM   13075 C  CE1   . HIS D 2 393 ? 398.631 395.572 213.322 1.00 116.03 ? 393 HIS D CE1   1 
ATOM   13076 N  NE2   . HIS D 2 393 ? 399.818 396.092 213.066 1.00 114.98 ? 393 HIS D NE2   1 
ATOM   13077 N  N     . LYS D 2 394 ? 399.694 390.503 212.219 1.00 94.36  ? 394 LYS D N     1 
ATOM   13078 C  CA    . LYS D 2 394 ? 399.436 389.672 213.392 1.00 91.77  ? 394 LYS D CA    1 
ATOM   13079 C  C     . LYS D 2 394 ? 400.706 388.970 213.859 1.00 95.27  ? 394 LYS D C     1 
ATOM   13080 O  O     . LYS D 2 394 ? 401.007 388.933 215.063 1.00 107.88 ? 394 LYS D O     1 
ATOM   13081 C  CB    . LYS D 2 394 ? 398.345 388.652 213.065 1.00 91.61  ? 394 LYS D CB    1 
ATOM   13082 C  CG    . LYS D 2 394 ? 396.963 389.273 212.882 1.00 95.62  ? 394 LYS D CG    1 
ATOM   13083 C  CD    . LYS D 2 394 ? 395.958 388.306 212.260 1.00 98.40  ? 394 LYS D CD    1 
ATOM   13084 C  CE    . LYS D 2 394 ? 395.394 387.327 213.279 1.00 104.62 ? 394 LYS D CE    1 
ATOM   13085 N  NZ    . LYS D 2 394 ? 394.238 386.564 212.734 1.00 99.51  ? 394 LYS D NZ    1 
ATOM   13086 N  N     . PHE D 2 395 ? 401.473 388.421 212.912 1.00 97.85  ? 395 PHE D N     1 
ATOM   13087 C  CA    . PHE D 2 395 ? 402.725 387.756 213.254 1.00 104.35 ? 395 PHE D CA    1 
ATOM   13088 C  C     . PHE D 2 395 ? 403.713 388.734 213.871 1.00 103.31 ? 395 PHE D C     1 
ATOM   13089 O  O     . PHE D 2 395 ? 404.426 388.387 214.815 1.00 106.26 ? 395 PHE D O     1 
ATOM   13090 C  CB    . PHE D 2 395 ? 403.329 387.103 212.009 1.00 103.71 ? 395 PHE D CB    1 
ATOM   13091 C  CG    . PHE D 2 395 ? 404.586 386.320 212.279 1.00 102.88 ? 395 PHE D CG    1 
ATOM   13092 C  CD1   . PHE D 2 395 ? 404.514 385.001 212.686 1.00 103.22 ? 395 PHE D CD1   1 
ATOM   13093 C  CD2   . PHE D 2 395 ? 405.835 386.895 212.117 1.00 99.46  ? 395 PHE D CD2   1 
ATOM   13094 C  CE1   . PHE D 2 395 ? 405.660 384.275 212.935 1.00 103.86 ? 395 PHE D CE1   1 
ATOM   13095 C  CE2   . PHE D 2 395 ? 406.982 386.173 212.370 1.00 99.00  ? 395 PHE D CE2   1 
ATOM   13096 C  CZ    . PHE D 2 395 ? 406.894 384.862 212.776 1.00 102.59 ? 395 PHE D CZ    1 
ATOM   13097 N  N     . ASP D 2 396 ? 403.787 389.953 213.334 1.00 101.68 ? 396 ASP D N     1 
ATOM   13098 C  CA    . ASP D 2 396 ? 404.697 390.953 213.880 1.00 99.42  ? 396 ASP D CA    1 
ATOM   13099 C  C     . ASP D 2 396 ? 404.308 391.328 215.300 1.00 101.92 ? 396 ASP D C     1 
ATOM   13100 O  O     . ASP D 2 396 ? 405.171 391.427 216.180 1.00 105.23 ? 396 ASP D O     1 
ATOM   13101 C  CB    . ASP D 2 396 ? 404.706 392.197 212.992 1.00 105.56 ? 396 ASP D CB    1 
ATOM   13102 C  CG    . ASP D 2 396 ? 405.315 391.941 211.628 1.00 114.61 ? 396 ASP D CG    1 
ATOM   13103 O  OD1   . ASP D 2 396 ? 405.995 390.909 211.452 1.00 119.84 ? 396 ASP D OD1   1 
ATOM   13104 O  OD2   . ASP D 2 396 ? 405.111 392.777 210.723 1.00 115.69 ? 396 ASP D OD2   1 
ATOM   13105 N  N     . LEU D 2 397 ? 403.007 391.526 215.542 1.00 107.06 ? 397 LEU D N     1 
ATOM   13106 C  CA    . LEU D 2 397 ? 402.543 391.868 216.883 1.00 107.24 ? 397 LEU D CA    1 
ATOM   13107 C  C     . LEU D 2 397 ? 402.866 390.763 217.876 1.00 105.73 ? 397 LEU D C     1 
ATOM   13108 O  O     . LEU D 2 397 ? 403.278 391.037 219.009 1.00 105.87 ? 397 LEU D O     1 
ATOM   13109 C  CB    . LEU D 2 397 ? 401.039 392.135 216.871 1.00 110.07 ? 397 LEU D CB    1 
ATOM   13110 C  CG    . LEU D 2 397 ? 400.550 393.489 216.357 1.00 110.46 ? 397 LEU D CG    1 
ATOM   13111 C  CD1   . LEU D 2 397 ? 399.048 393.428 216.127 1.00 106.50 ? 397 LEU D CD1   1 
ATOM   13112 C  CD2   . LEU D 2 397 ? 400.899 394.611 217.328 1.00 114.13 ? 397 LEU D CD2   1 
ATOM   13113 N  N     . MET D 2 398 ? 402.692 389.506 217.471 1.00 101.74 ? 398 MET D N     1 
ATOM   13114 C  CA    . MET D 2 398 ? 403.005 388.406 218.377 1.00 98.26  ? 398 MET D CA    1 
ATOM   13115 C  C     . MET D 2 398 ? 404.508 388.274 218.600 1.00 100.78 ? 398 MET D C     1 
ATOM   13116 O  O     . MET D 2 398 ? 404.967 388.139 219.740 1.00 106.09 ? 398 MET D O     1 
ATOM   13117 C  CB    . MET D 2 398 ? 402.436 387.105 217.829 1.00 104.71 ? 398 MET D CB    1 
ATOM   13118 C  CG    . MET D 2 398 ? 400.935 387.042 217.826 1.00 105.73 ? 398 MET D CG    1 
ATOM   13119 S  SD    . MET D 2 398 ? 400.375 385.939 219.120 1.00 113.35 ? 398 MET D SD    1 
ATOM   13120 C  CE    . MET D 2 398 ? 399.995 384.508 218.130 1.00 102.98 ? 398 MET D CE    1 
ATOM   13121 N  N     . TYR D 2 399 ? 405.290 388.312 217.523 1.00 102.19 ? 399 TYR D N     1 
ATOM   13122 C  CA    . TYR D 2 399 ? 406.707 387.988 217.584 1.00 98.36  ? 399 TYR D CA    1 
ATOM   13123 C  C     . TYR D 2 399 ? 407.559 389.121 218.139 1.00 100.55 ? 399 TYR D C     1 
ATOM   13124 O  O     . TYR D 2 399 ? 408.684 388.865 218.582 1.00 103.22 ? 399 TYR D O     1 
ATOM   13125 C  CB    . TYR D 2 399 ? 407.193 387.605 216.182 1.00 102.26 ? 399 TYR D CB    1 
ATOM   13126 C  CG    . TYR D 2 399 ? 408.627 387.137 216.111 1.00 101.26 ? 399 TYR D CG    1 
ATOM   13127 C  CD1   . TYR D 2 399 ? 409.027 385.962 216.729 1.00 101.45 ? 399 TYR D CD1   1 
ATOM   13128 C  CD2   . TYR D 2 399 ? 409.579 387.872 215.422 1.00 103.51 ? 399 TYR D CD2   1 
ATOM   13129 C  CE1   . TYR D 2 399 ? 410.335 385.533 216.662 1.00 104.38 ? 399 TYR D CE1   1 
ATOM   13130 C  CE2   . TYR D 2 399 ? 410.888 387.452 215.351 1.00 105.11 ? 399 TYR D CE2   1 
ATOM   13131 C  CZ    . TYR D 2 399 ? 411.262 386.284 215.975 1.00 107.94 ? 399 TYR D CZ    1 
ATOM   13132 O  OH    . TYR D 2 399 ? 412.567 385.863 215.900 1.00 111.00 ? 399 TYR D OH    1 
ATOM   13133 N  N     . ALA D 2 400 ? 407.057 390.361 218.135 1.00 105.28 ? 400 ALA D N     1 
ATOM   13134 C  CA    . ALA D 2 400 ? 407.824 391.462 218.707 1.00 106.76 ? 400 ALA D CA    1 
ATOM   13135 C  C     . ALA D 2 400 ? 408.066 391.261 220.195 1.00 105.78 ? 400 ALA D C     1 
ATOM   13136 O  O     . ALA D 2 400 ? 409.116 391.662 220.710 1.00 109.70 ? 400 ALA D O     1 
ATOM   13137 C  CB    . ALA D 2 400 ? 407.102 392.785 218.461 1.00 102.20 ? 400 ALA D CB    1 
ATOM   13138 N  N     . LYS D 2 401 ? 407.114 390.642 220.893 1.00 97.65  ? 401 LYS D N     1 
ATOM   13139 C  CA    . LYS D 2 401 ? 407.224 390.330 222.312 1.00 98.73  ? 401 LYS D CA    1 
ATOM   13140 C  C     . LYS D 2 401 ? 407.549 388.865 222.587 1.00 98.17  ? 401 LYS D C     1 
ATOM   13141 O  O     . LYS D 2 401 ? 407.614 388.478 223.757 1.00 98.68  ? 401 LYS D O     1 
ATOM   13142 C  CB    . LYS D 2 401 ? 405.920 390.712 223.014 1.00 93.60  ? 401 LYS D CB    1 
ATOM   13143 C  CG    . LYS D 2 401 ? 405.745 392.208 223.157 1.00 98.11  ? 401 LYS D CG    1 
ATOM   13144 C  CD    . LYS D 2 401 ? 404.434 392.559 223.823 1.00 97.50  ? 401 LYS D CD    1 
ATOM   13145 C  CE    . LYS D 2 401 ? 404.402 394.019 224.231 1.00 102.76 ? 401 LYS D CE    1 
ATOM   13146 N  NZ    . LYS D 2 401 ? 404.581 394.933 223.068 1.00 102.20 ? 401 LYS D NZ    1 
ATOM   13147 N  N     . ARG D 2 402 ? 407.775 388.049 221.550 1.00 105.65 ? 402 ARG D N     1 
ATOM   13148 C  CA    . ARG D 2 402 ? 408.017 386.612 221.695 1.00 103.53 ? 402 ARG D CA    1 
ATOM   13149 C  C     . ARG D 2 402 ? 406.845 385.948 222.421 1.00 99.22  ? 402 ARG D C     1 
ATOM   13150 O  O     . ARG D 2 402 ? 406.991 385.350 223.488 1.00 97.47  ? 402 ARG D O     1 
ATOM   13151 C  CB    . ARG D 2 402 ? 409.345 386.342 222.415 1.00 102.18 ? 402 ARG D CB    1 
ATOM   13152 C  CG    . ARG D 2 402 ? 410.563 387.009 221.774 1.00 102.54 ? 402 ARG D CG    1 
ATOM   13153 C  CD    . ARG D 2 402 ? 410.846 386.455 220.387 1.00 107.54 ? 402 ARG D CD    1 
ATOM   13154 N  NE    . ARG D 2 402 ? 412.210 386.738 219.948 1.00 109.74 ? 402 ARG D NE    1 
ATOM   13155 C  CZ    . ARG D 2 402 ? 412.613 387.847 219.336 1.00 108.75 ? 402 ARG D CZ    1 
ATOM   13156 N  NH1   . ARG D 2 402 ? 411.787 388.854 219.084 1.00 101.67 ? 402 ARG D NH1   1 
ATOM   13157 N  NH2   . ARG D 2 402 ? 413.887 387.954 218.968 1.00 109.45 ? 402 ARG D NH2   1 
ATOM   13158 N  N     . ALA D 2 403 ? 405.668 386.072 221.805 1.00 95.95  ? 403 ALA D N     1 
ATOM   13159 C  CA    . ALA D 2 403 ? 404.420 385.771 222.498 1.00 95.39  ? 403 ALA D CA    1 
ATOM   13160 C  C     . ALA D 2 403 ? 404.292 384.292 222.837 1.00 93.88  ? 403 ALA D C     1 
ATOM   13161 O  O     . ALA D 2 403 ? 403.801 383.950 223.915 1.00 96.75  ? 403 ALA D O     1 
ATOM   13162 C  CB    . ALA D 2 403 ? 403.232 386.222 221.651 1.00 99.30  ? 403 ALA D CB    1 
ATOM   13163 N  N     . PHE D 2 404 ? 404.685 383.401 221.914 1.00 91.58  ? 404 PHE D N     1 
ATOM   13164 C  CA    . PHE D 2 404 ? 404.565 381.958 222.114 1.00 96.30  ? 404 PHE D CA    1 
ATOM   13165 C  C     . PHE D 2 404 ? 405.795 381.214 221.603 1.00 94.74  ? 404 PHE D C     1 
ATOM   13166 O  O     . PHE D 2 404 ? 405.705 380.021 221.293 1.00 91.82  ? 404 PHE D O     1 
ATOM   13167 C  CB    . PHE D 2 404 ? 403.310 381.402 221.416 1.00 93.93  ? 404 PHE D CB    1 
ATOM   13168 C  CG    . PHE D 2 404 ? 402.020 381.999 221.905 1.00 90.08  ? 404 PHE D CG    1 
ATOM   13169 C  CD1   . PHE D 2 404 ? 401.530 383.179 221.371 1.00 95.45  ? 404 PHE D CD1   1 
ATOM   13170 C  CD2   . PHE D 2 404 ? 401.292 381.369 222.894 1.00 86.48  ? 404 PHE D CD2   1 
ATOM   13171 C  CE1   . PHE D 2 404 ? 400.348 383.721 221.828 1.00 94.74  ? 404 PHE D CE1   1 
ATOM   13172 C  CE2   . PHE D 2 404 ? 400.110 381.907 223.354 1.00 85.94  ? 404 PHE D CE2   1 
ATOM   13173 C  CZ    . PHE D 2 404 ? 399.636 383.083 222.819 1.00 92.50  ? 404 PHE D CZ    1 
ATOM   13174 N  N     . VAL D 2 405 ? 406.946 381.882 221.525 1.00 89.76  ? 405 VAL D N     1 
ATOM   13175 C  CA    . VAL D 2 405 ? 408.087 381.306 220.825 1.00 88.05  ? 405 VAL D CA    1 
ATOM   13176 C  C     . VAL D 2 405 ? 408.718 380.171 221.624 1.00 90.60  ? 405 VAL D C     1 
ATOM   13177 O  O     . VAL D 2 405 ? 409.376 379.298 221.046 1.00 101.40 ? 405 VAL D O     1 
ATOM   13178 C  CB    . VAL D 2 405 ? 409.110 382.411 220.493 1.00 97.97  ? 405 VAL D CB    1 
ATOM   13179 C  CG1   . VAL D 2 405 ? 410.341 381.823 219.799 1.00 101.66 ? 405 VAL D CG1   1 
ATOM   13180 C  CG2   . VAL D 2 405 ? 408.460 383.493 219.621 1.00 101.99 ? 405 VAL D CG2   1 
ATOM   13181 N  N     . HIS D 2 406 ? 408.547 380.153 222.950 1.00 85.97  ? 406 HIS D N     1 
ATOM   13182 C  CA    . HIS D 2 406 ? 409.222 379.134 223.749 1.00 92.14  ? 406 HIS D CA    1 
ATOM   13183 C  C     . HIS D 2 406 ? 408.649 377.743 223.498 1.00 92.48  ? 406 HIS D C     1 
ATOM   13184 O  O     . HIS D 2 406 ? 409.392 376.758 223.558 1.00 92.71  ? 406 HIS D O     1 
ATOM   13185 C  CB    . HIS D 2 406 ? 409.157 379.495 225.236 1.00 92.20  ? 406 HIS D CB    1 
ATOM   13186 C  CG    . HIS D 2 406 ? 407.838 379.207 225.880 1.00 94.00  ? 406 HIS D CG    1 
ATOM   13187 N  ND1   . HIS D 2 406 ? 407.563 378.011 226.508 1.00 91.63  ? 406 HIS D ND1   1 
ATOM   13188 C  CD2   . HIS D 2 406 ? 406.720 379.959 225.996 1.00 92.95  ? 406 HIS D CD2   1 
ATOM   13189 C  CE1   . HIS D 2 406 ? 406.330 378.039 226.981 1.00 96.51  ? 406 HIS D CE1   1 
ATOM   13190 N  NE2   . HIS D 2 406 ? 405.796 379.210 226.683 1.00 97.86  ? 406 HIS D NE2   1 
ATOM   13191 N  N     . TRP D 2 407 ? 407.353 377.640 223.184 1.00 94.45  ? 407 TRP D N     1 
ATOM   13192 C  CA    . TRP D 2 407 ? 406.778 376.343 222.841 1.00 92.35  ? 407 TRP D CA    1 
ATOM   13193 C  C     . TRP D 2 407 ? 407.402 375.787 221.571 1.00 91.44  ? 407 TRP D C     1 
ATOM   13194 O  O     . TRP D 2 407 ? 407.657 374.581 221.469 1.00 88.28  ? 407 TRP D O     1 
ATOM   13195 C  CB    . TRP D 2 407 ? 405.265 376.463 222.670 1.00 84.82  ? 407 TRP D CB    1 
ATOM   13196 C  CG    . TRP D 2 407 ? 404.520 376.600 223.948 1.00 89.07  ? 407 TRP D CG    1 
ATOM   13197 C  CD1   . TRP D 2 407 ? 403.811 377.682 224.370 1.00 87.04  ? 407 TRP D CD1   1 
ATOM   13198 C  CD2   . TRP D 2 407 ? 404.395 375.612 224.974 1.00 94.44  ? 407 TRP D CD2   1 
ATOM   13199 N  NE1   . TRP D 2 407 ? 403.256 377.433 225.598 1.00 91.76  ? 407 TRP D NE1   1 
ATOM   13200 C  CE2   . TRP D 2 407 ? 403.599 376.166 225.992 1.00 93.18  ? 407 TRP D CE2   1 
ATOM   13201 C  CE3   . TRP D 2 407 ? 404.881 374.311 225.132 1.00 94.84  ? 407 TRP D CE3   1 
ATOM   13202 C  CZ2   . TRP D 2 407 ? 403.280 375.465 227.152 1.00 91.16  ? 407 TRP D CZ2   1 
ATOM   13203 C  CZ3   . TRP D 2 407 ? 404.563 373.619 226.283 1.00 90.82  ? 407 TRP D CZ3   1 
ATOM   13204 C  CH2   . TRP D 2 407 ? 403.770 374.197 227.277 1.00 91.82  ? 407 TRP D CH2   1 
ATOM   13205 N  N     . TYR D 2 408 ? 407.651 376.652 220.590 1.00 102.88 ? 408 TYR D N     1 
ATOM   13206 C  CA    . TYR D 2 408 ? 408.250 376.204 219.340 1.00 98.89  ? 408 TYR D CA    1 
ATOM   13207 C  C     . TYR D 2 408 ? 409.730 375.901 219.524 1.00 96.70  ? 408 TYR D C     1 
ATOM   13208 O  O     . TYR D 2 408 ? 410.260 374.964 218.917 1.00 101.47 ? 408 TYR D O     1 
ATOM   13209 C  CB    . TYR D 2 408 ? 408.048 377.263 218.256 1.00 100.86 ? 408 TYR D CB    1 
ATOM   13210 C  CG    . TYR D 2 408 ? 406.605 377.456 217.838 1.00 95.71  ? 408 TYR D CG    1 
ATOM   13211 C  CD1   . TYR D 2 408 ? 405.726 378.193 218.620 1.00 97.22  ? 408 TYR D CD1   1 
ATOM   13212 C  CD2   . TYR D 2 408 ? 406.123 376.904 216.661 1.00 98.09  ? 408 TYR D CD2   1 
ATOM   13213 C  CE1   . TYR D 2 408 ? 404.414 378.368 218.248 1.00 96.35  ? 408 TYR D CE1   1 
ATOM   13214 C  CE2   . TYR D 2 408 ? 404.808 377.078 216.280 1.00 94.60  ? 408 TYR D CE2   1 
ATOM   13215 C  CZ    . TYR D 2 408 ? 403.960 377.811 217.079 1.00 93.51  ? 408 TYR D CZ    1 
ATOM   13216 O  OH    . TYR D 2 408 ? 402.649 377.991 216.709 1.00 104.15 ? 408 TYR D OH    1 
ATOM   13217 N  N     . VAL D 2 409 ? 410.414 376.686 220.358 1.00 95.70  ? 409 VAL D N     1 
ATOM   13218 C  CA    . VAL D 2 409 ? 411.834 376.458 220.599 1.00 94.42  ? 409 VAL D CA    1 
ATOM   13219 C  C     . VAL D 2 409 ? 412.046 375.164 221.371 1.00 98.77  ? 409 VAL D C     1 
ATOM   13220 O  O     . VAL D 2 409 ? 413.054 374.475 221.170 1.00 101.02 ? 409 VAL D O     1 
ATOM   13221 C  CB    . VAL D 2 409 ? 412.450 377.670 221.326 1.00 96.41  ? 409 VAL D CB    1 
ATOM   13222 C  CG1   . VAL D 2 409 ? 413.853 377.351 221.842 1.00 99.20  ? 409 VAL D CG1   1 
ATOM   13223 C  CG2   . VAL D 2 409 ? 412.512 378.874 220.395 1.00 98.27  ? 409 VAL D CG2   1 
ATOM   13224 N  N     . GLY D 2 410 ? 411.124 374.819 222.274 1.00 98.74  ? 410 GLY D N     1 
ATOM   13225 C  CA    . GLY D 2 410 ? 411.240 373.564 222.995 1.00 101.67 ? 410 GLY D CA    1 
ATOM   13226 C  C     . GLY D 2 410 ? 411.192 372.352 222.088 1.00 99.62  ? 410 GLY D C     1 
ATOM   13227 O  O     . GLY D 2 410 ? 411.872 371.355 222.344 1.00 96.48  ? 410 GLY D O     1 
ATOM   13228 N  N     . GLU D 2 411 ? 410.403 372.423 221.018 1.00 112.87 ? 411 GLU D N     1 
ATOM   13229 C  CA    . GLU D 2 411 ? 410.266 371.333 220.061 1.00 109.41 ? 411 GLU D CA    1 
ATOM   13230 C  C     . GLU D 2 411 ? 411.274 371.421 218.915 1.00 110.07 ? 411 GLU D C     1 
ATOM   13231 O  O     . GLU D 2 411 ? 411.060 370.803 217.869 1.00 107.85 ? 411 GLU D O     1 
ATOM   13232 C  CB    . GLU D 2 411 ? 408.838 371.305 219.501 1.00 112.12 ? 411 GLU D CB    1 
ATOM   13233 C  CG    . GLU D 2 411 ? 407.723 371.155 220.546 1.00 118.24 ? 411 GLU D CG    1 
ATOM   13234 C  CD    . GLU D 2 411 ? 407.592 369.745 221.091 1.00 120.63 ? 411 GLU D CD    1 
ATOM   13235 O  OE1   . GLU D 2 411 ? 408.466 368.903 220.807 1.00 121.74 ? 411 GLU D OE1   1 
ATOM   13236 O  OE2   . GLU D 2 411 ? 406.613 369.481 221.819 1.00 120.13 ? 411 GLU D OE2   1 
ATOM   13237 N  N     . GLY D 2 412 ? 412.353 372.186 219.075 1.00 117.12 ? 412 GLY D N     1 
ATOM   13238 C  CA    . GLY D 2 412 ? 413.468 372.111 218.150 1.00 115.91 ? 412 GLY D CA    1 
ATOM   13239 C  C     . GLY D 2 412 ? 413.389 372.970 216.902 1.00 114.92 ? 412 GLY D C     1 
ATOM   13240 O  O     . GLY D 2 412 ? 413.453 372.443 215.787 1.00 113.06 ? 412 GLY D O     1 
ATOM   13241 N  N     . MET D 2 413 ? 413.246 374.284 217.063 1.00 113.67 ? 413 MET D N     1 
ATOM   13242 C  CA    . MET D 2 413 ? 413.523 375.220 215.981 1.00 113.32 ? 413 MET D CA    1 
ATOM   13243 C  C     . MET D 2 413 ? 414.022 376.527 216.577 1.00 119.37 ? 413 MET D C     1 
ATOM   13244 O  O     . MET D 2 413 ? 413.744 376.853 217.733 1.00 120.88 ? 413 MET D O     1 
ATOM   13245 C  CB    . MET D 2 413 ? 412.302 375.483 215.087 1.00 111.97 ? 413 MET D CB    1 
ATOM   13246 C  CG    . MET D 2 413 ? 411.024 375.892 215.826 1.00 111.69 ? 413 MET D CG    1 
ATOM   13247 S  SD    . MET D 2 413 ? 409.579 376.349 214.819 1.00 124.39 ? 413 MET D SD    1 
ATOM   13248 C  CE    . MET D 2 413 ? 410.246 377.113 213.346 1.00 113.62 ? 413 MET D CE    1 
ATOM   13249 N  N     . GLU D 2 414 ? 414.758 377.277 215.763 1.00 126.86 ? 414 GLU D N     1 
ATOM   13250 C  CA    . GLU D 2 414 ? 415.395 378.517 216.181 1.00 124.57 ? 414 GLU D CA    1 
ATOM   13251 C  C     . GLU D 2 414 ? 414.552 379.722 215.777 1.00 122.86 ? 414 GLU D C     1 
ATOM   13252 O  O     . GLU D 2 414 ? 413.678 379.643 214.911 1.00 128.91 ? 414 GLU D O     1 
ATOM   13253 C  CB    . GLU D 2 414 ? 416.793 378.639 215.570 1.00 126.69 ? 414 GLU D CB    1 
ATOM   13254 C  CG    . GLU D 2 414 ? 417.821 377.640 216.111 1.00 129.53 ? 414 GLU D CG    1 
ATOM   13255 C  CD    . GLU D 2 414 ? 417.697 376.242 215.519 1.00 129.55 ? 414 GLU D CD    1 
ATOM   13256 O  OE1   . GLU D 2 414 ? 416.889 376.044 214.587 1.00 127.67 ? 414 GLU D OE1   1 
ATOM   13257 O  OE2   . GLU D 2 414 ? 418.413 375.336 215.992 1.00 128.20 ? 414 GLU D OE2   1 
ATOM   13258 N  N     . GLU D 2 415 ? 414.834 380.855 216.424 1.00 115.64 ? 415 GLU D N     1 
ATOM   13259 C  CA    . GLU D 2 415 ? 414.198 382.114 216.056 1.00 121.01 ? 415 GLU D CA    1 
ATOM   13260 C  C     . GLU D 2 415 ? 414.622 382.591 214.671 1.00 122.90 ? 415 GLU D C     1 
ATOM   13261 O  O     . GLU D 2 415 ? 413.907 383.393 214.053 1.00 128.51 ? 415 GLU D O     1 
ATOM   13262 C  CB    . GLU D 2 415 ? 414.528 383.180 217.099 1.00 124.54 ? 415 GLU D CB    1 
ATOM   13263 C  CG    . GLU D 2 415 ? 414.110 382.802 218.509 1.00 123.63 ? 415 GLU D CG    1 
ATOM   13264 C  CD    . GLU D 2 415 ? 414.124 383.982 219.458 1.00 128.35 ? 415 GLU D CD    1 
ATOM   13265 O  OE1   . GLU D 2 415 ? 414.746 385.011 219.122 1.00 128.52 ? 415 GLU D OE1   1 
ATOM   13266 O  OE2   . GLU D 2 415 ? 413.514 383.880 220.543 1.00 127.73 ? 415 GLU D OE2   1 
ATOM   13267 N  N     . GLY D 2 416 ? 415.777 382.131 214.183 1.00 121.35 ? 416 GLY D N     1 
ATOM   13268 C  CA    . GLY D 2 416 ? 416.168 382.430 212.820 1.00 123.25 ? 416 GLY D CA    1 
ATOM   13269 C  C     . GLY D 2 416 ? 415.176 381.909 211.803 1.00 123.54 ? 416 GLY D C     1 
ATOM   13270 O  O     . GLY D 2 416 ? 414.952 382.545 210.774 1.00 125.97 ? 416 GLY D O     1 
ATOM   13271 N  N     . GLU D 2 417 ? 414.563 380.756 212.075 1.00 119.31 ? 417 GLU D N     1 
ATOM   13272 C  CA    . GLU D 2 417 ? 413.534 380.245 211.176 1.00 120.93 ? 417 GLU D CA    1 
ATOM   13273 C  C     . GLU D 2 417 ? 412.310 381.154 211.163 1.00 120.52 ? 417 GLU D C     1 
ATOM   13274 O  O     . GLU D 2 417 ? 411.715 381.382 210.104 1.00 127.23 ? 417 GLU D O     1 
ATOM   13275 C  CB    . GLU D 2 417 ? 413.149 378.822 211.574 1.00 122.53 ? 417 GLU D CB    1 
ATOM   13276 C  CG    . GLU D 2 417 ? 412.148 378.174 210.631 1.00 123.50 ? 417 GLU D CG    1 
ATOM   13277 C  CD    . GLU D 2 417 ? 412.347 376.676 210.500 1.00 127.84 ? 417 GLU D CD    1 
ATOM   13278 O  OE1   . GLU D 2 417 ? 412.746 376.034 211.494 1.00 129.22 ? 417 GLU D OE1   1 
ATOM   13279 O  OE2   . GLU D 2 417 ? 412.101 376.138 209.400 1.00 128.01 ? 417 GLU D OE2   1 
ATOM   13280 N  N     . PHE D 2 418 ? 411.921 381.681 212.328 1.00 99.53  ? 418 PHE D N     1 
ATOM   13281 C  CA    . PHE D 2 418 ? 410.808 382.627 212.389 1.00 100.80 ? 418 PHE D CA    1 
ATOM   13282 C  C     . PHE D 2 418 ? 411.115 383.879 211.578 1.00 102.04 ? 418 PHE D C     1 
ATOM   13283 O  O     . PHE D 2 418 ? 410.284 384.351 210.788 1.00 105.67 ? 418 PHE D O     1 
ATOM   13284 C  CB    . PHE D 2 418 ? 410.525 383.004 213.844 1.00 97.87  ? 418 PHE D CB    1 
ATOM   13285 C  CG    . PHE D 2 418 ? 409.642 382.031 214.567 1.00 101.11 ? 418 PHE D CG    1 
ATOM   13286 C  CD1   . PHE D 2 418 ? 410.118 380.785 214.930 1.00 105.27 ? 418 PHE D CD1   1 
ATOM   13287 C  CD2   . PHE D 2 418 ? 408.343 382.369 214.898 1.00 101.26 ? 418 PHE D CD2   1 
ATOM   13288 C  CE1   . PHE D 2 418 ? 409.311 379.890 215.599 1.00 110.20 ? 418 PHE D CE1   1 
ATOM   13289 C  CE2   . PHE D 2 418 ? 407.532 381.478 215.568 1.00 102.89 ? 418 PHE D CE2   1 
ATOM   13290 C  CZ    . PHE D 2 418 ? 408.017 380.237 215.920 1.00 107.64 ? 418 PHE D CZ    1 
ATOM   13291 N  N     . SER D 2 419 ? 412.320 384.423 211.760 1.00 103.49 ? 419 SER D N     1 
ATOM   13292 C  CA    . SER D 2 419 ? 412.708 385.624 211.026 1.00 103.73 ? 419 SER D CA    1 
ATOM   13293 C  C     . SER D 2 419 ? 412.778 385.355 209.528 1.00 107.68 ? 419 SER D C     1 
ATOM   13294 O  O     . SER D 2 419 ? 412.372 386.197 208.719 1.00 106.52 ? 419 SER D O     1 
ATOM   13295 C  CB    . SER D 2 419 ? 414.049 386.140 211.541 1.00 108.07 ? 419 SER D CB    1 
ATOM   13296 O  OG    . SER D 2 419 ? 415.114 385.323 211.090 1.00 114.70 ? 419 SER D OG    1 
ATOM   13297 N  N     . GLU D 2 420 ? 413.282 384.181 209.140 1.00 112.82 ? 420 GLU D N     1 
ATOM   13298 C  CA    . GLU D 2 420 ? 413.357 383.826 207.728 1.00 112.84 ? 420 GLU D CA    1 
ATOM   13299 C  C     . GLU D 2 420 ? 411.970 383.682 207.118 1.00 117.45 ? 420 GLU D C     1 
ATOM   13300 O  O     . GLU D 2 420 ? 411.745 384.098 205.976 1.00 122.24 ? 420 GLU D O     1 
ATOM   13301 C  CB    . GLU D 2 420 ? 414.148 382.532 207.560 1.00 113.77 ? 420 GLU D CB    1 
ATOM   13302 C  CG    . GLU D 2 420 ? 415.647 382.710 207.686 1.00 115.29 ? 420 GLU D CG    1 
ATOM   13303 C  CD    . GLU D 2 420 ? 416.379 381.391 207.811 1.00 120.59 ? 420 GLU D CD    1 
ATOM   13304 O  OE1   . GLU D 2 420 ? 415.849 380.369 207.326 1.00 117.93 ? 420 GLU D OE1   1 
ATOM   13305 O  OE2   . GLU D 2 420 ? 417.482 381.375 208.395 1.00 123.25 ? 420 GLU D OE2   1 
ATOM   13306 N  N     . ALA D 2 421 ? 411.032 383.081 207.854 1.00 111.00 ? 421 ALA D N     1 
ATOM   13307 C  CA    . ALA D 2 421 ? 409.668 382.964 207.351 1.00 109.91 ? 421 ALA D CA    1 
ATOM   13308 C  C     . ALA D 2 421 ? 409.031 384.335 207.172 1.00 113.37 ? 421 ALA D C     1 
ATOM   13309 O  O     . ALA D 2 421 ? 408.352 384.589 206.167 1.00 114.28 ? 421 ALA D O     1 
ATOM   13310 C  CB    . ALA D 2 421 ? 408.832 382.103 208.296 1.00 107.74 ? 421 ALA D CB    1 
ATOM   13311 N  N     . ARG D 2 422 ? 409.250 385.239 208.131 1.00 112.13 ? 422 ARG D N     1 
ATOM   13312 C  CA    . ARG D 2 422 ? 408.700 386.584 207.993 1.00 109.52 ? 422 ARG D CA    1 
ATOM   13313 C  C     . ARG D 2 422 ? 409.331 387.316 206.814 1.00 106.89 ? 422 ARG D C     1 
ATOM   13314 O  O     . ARG D 2 422 ? 408.647 388.054 206.095 1.00 108.85 ? 422 ARG D O     1 
ATOM   13315 C  CB    . ARG D 2 422 ? 408.897 387.372 209.290 1.00 106.79 ? 422 ARG D CB    1 
ATOM   13316 C  CG    . ARG D 2 422 ? 408.421 388.840 209.269 1.00 108.36 ? 422 ARG D CG    1 
ATOM   13317 C  CD    . ARG D 2 422 ? 406.957 389.011 208.852 1.00 108.71 ? 422 ARG D CD    1 
ATOM   13318 N  NE    . ARG D 2 422 ? 406.553 390.418 208.890 1.00 113.82 ? 422 ARG D NE    1 
ATOM   13319 C  CZ    . ARG D 2 422 ? 406.205 391.183 207.857 1.00 113.57 ? 422 ARG D CZ    1 
ATOM   13320 N  NH1   . ARG D 2 422 ? 406.242 390.750 206.603 1.00 109.90 ? 422 ARG D NH1   1 
ATOM   13321 N  NH2   . ARG D 2 422 ? 405.815 392.433 208.087 1.00 112.37 ? 422 ARG D NH2   1 
ATOM   13322 N  N     . GLU D 2 423 ? 410.636 387.130 206.604 1.00 101.26 ? 423 GLU D N     1 
ATOM   13323 C  CA    . GLU D 2 423 ? 411.300 387.748 205.460 1.00 107.10 ? 423 GLU D CA    1 
ATOM   13324 C  C     . GLU D 2 423 ? 410.752 387.207 204.147 1.00 109.86 ? 423 GLU D C     1 
ATOM   13325 O  O     . GLU D 2 423 ? 410.549 387.962 203.188 1.00 111.17 ? 423 GLU D O     1 
ATOM   13326 C  CB    . GLU D 2 423 ? 412.805 387.509 205.546 1.00 108.48 ? 423 GLU D CB    1 
ATOM   13327 C  CG    . GLU D 2 423 ? 413.507 388.393 206.555 1.00 113.17 ? 423 GLU D CG    1 
ATOM   13328 C  CD    . GLU D 2 423 ? 414.977 388.056 206.697 1.00 115.31 ? 423 GLU D CD    1 
ATOM   13329 O  OE1   . GLU D 2 423 ? 415.481 387.243 205.895 1.00 114.85 ? 423 GLU D OE1   1 
ATOM   13330 O  OE2   . GLU D 2 423 ? 415.627 388.603 207.612 1.00 112.14 ? 423 GLU D OE2   1 
ATOM   13331 N  N     . ASP D 2 424 ? 410.510 385.896 204.085 1.00 111.38 ? 424 ASP D N     1 
ATOM   13332 C  CA    . ASP D 2 424 ? 409.934 385.309 202.883 1.00 114.06 ? 424 ASP D CA    1 
ATOM   13333 C  C     . ASP D 2 424 ? 408.538 385.855 202.623 1.00 114.37 ? 424 ASP D C     1 
ATOM   13334 O  O     . ASP D 2 424 ? 408.163 386.091 201.470 1.00 118.45 ? 424 ASP D O     1 
ATOM   13335 C  CB    . ASP D 2 424 ? 409.893 383.786 203.006 1.00 115.60 ? 424 ASP D CB    1 
ATOM   13336 C  CG    . ASP D 2 424 ? 409.617 383.101 201.680 1.00 116.74 ? 424 ASP D CG    1 
ATOM   13337 O  OD1   . ASP D 2 424 ? 410.134 383.564 200.642 1.00 115.37 ? 424 ASP D OD1   1 
ATOM   13338 O  OD2   . ASP D 2 424 ? 408.873 382.100 201.670 1.00 119.26 ? 424 ASP D OD2   1 
ATOM   13339 N  N     . MET D 2 425 ? 407.755 386.070 203.680 1.00 114.50 ? 425 MET D N     1 
ATOM   13340 C  CA    . MET D 2 425 ? 406.408 386.594 203.475 1.00 118.23 ? 425 MET D CA    1 
ATOM   13341 C  C     . MET D 2 425 ? 406.443 388.058 203.058 1.00 116.70 ? 425 MET D C     1 
ATOM   13342 O  O     . MET D 2 425 ? 405.606 388.500 202.255 1.00 114.48 ? 425 MET D O     1 
ATOM   13343 C  CB    . MET D 2 425 ? 405.584 386.404 204.741 1.00 116.47 ? 425 MET D CB    1 
ATOM   13344 C  CG    . MET D 2 425 ? 404.109 386.225 204.442 1.00 114.10 ? 425 MET D CG    1 
ATOM   13345 S  SD    . MET D 2 425 ? 403.617 384.611 203.745 1.00 126.58 ? 425 MET D SD    1 
ATOM   13346 C  CE    . MET D 2 425 ? 404.937 383.448 204.152 1.00 118.95 ? 425 MET D CE    1 
ATOM   13347 N  N     . ALA D 2 426 ? 407.409 388.814 203.585 1.00 106.08 ? 426 ALA D N     1 
ATOM   13348 C  CA    . ALA D 2 426 ? 407.648 390.167 203.100 1.00 102.39 ? 426 ALA D CA    1 
ATOM   13349 C  C     . ALA D 2 426 ? 407.956 390.153 201.611 1.00 105.85 ? 426 ALA D C     1 
ATOM   13350 O  O     . ALA D 2 426 ? 407.395 390.941 200.842 1.00 113.38 ? 426 ALA D O     1 
ATOM   13351 C  CB    . ALA D 2 426 ? 408.799 390.802 203.880 1.00 101.98 ? 426 ALA D CB    1 
ATOM   13352 N  N     . ALA D 2 427 ? 408.826 389.232 201.188 1.00 106.69 ? 427 ALA D N     1 
ATOM   13353 C  CA    . ALA D 2 427 ? 409.158 389.110 199.771 1.00 109.18 ? 427 ALA D CA    1 
ATOM   13354 C  C     . ALA D 2 427 ? 407.934 388.736 198.944 1.00 111.43 ? 427 ALA D C     1 
ATOM   13355 O  O     . ALA D 2 427 ? 407.762 389.224 197.821 1.00 117.55 ? 427 ALA D O     1 
ATOM   13356 C  CB    . ALA D 2 427 ? 410.265 388.074 199.583 1.00 107.55 ? 427 ALA D CB    1 
ATOM   13357 N  N     . LEU D 2 428 ? 407.073 387.870 199.486 1.00 111.09 ? 428 LEU D N     1 
ATOM   13358 C  CA    . LEU D 2 428 ? 405.860 387.474 198.774 1.00 112.85 ? 428 LEU D CA    1 
ATOM   13359 C  C     . LEU D 2 428 ? 404.948 388.671 198.534 1.00 114.89 ? 428 LEU D C     1 
ATOM   13360 O  O     . LEU D 2 428 ? 404.442 388.869 197.423 1.00 121.84 ? 428 LEU D O     1 
ATOM   13361 C  CB    . LEU D 2 428 ? 405.119 386.388 199.560 1.00 108.45 ? 428 LEU D CB    1 
ATOM   13362 C  CG    . LEU D 2 428 ? 403.808 385.839 198.977 1.00 110.07 ? 428 LEU D CG    1 
ATOM   13363 C  CD1   . LEU D 2 428 ? 404.028 385.236 197.595 1.00 110.15 ? 428 LEU D CD1   1 
ATOM   13364 C  CD2   . LEU D 2 428 ? 403.189 384.825 199.924 1.00 112.81 ? 428 LEU D CD2   1 
ATOM   13365 N  N     . GLU D 2 429 ? 404.725 389.485 199.568 1.00 114.09 ? 429 GLU D N     1 
ATOM   13366 C  CA    . GLU D 2 429 ? 403.831 390.626 199.384 1.00 111.46 ? 429 GLU D CA    1 
ATOM   13367 C  C     . GLU D 2 429 ? 404.474 391.718 198.530 1.00 111.87 ? 429 GLU D C     1 
ATOM   13368 O  O     . GLU D 2 429 ? 403.763 392.419 197.795 1.00 113.70 ? 429 GLU D O     1 
ATOM   13369 C  CB    . GLU D 2 429 ? 403.357 391.174 200.733 1.00 110.78 ? 429 GLU D CB    1 
ATOM   13370 C  CG    . GLU D 2 429 ? 404.424 391.711 201.650 1.00 123.94 ? 429 GLU D CG    1 
ATOM   13371 C  CD    . GLU D 2 429 ? 403.870 392.091 203.008 1.00 123.37 ? 429 GLU D CD    1 
ATOM   13372 O  OE1   . GLU D 2 429 ? 402.725 392.585 203.068 1.00 118.35 ? 429 GLU D OE1   1 
ATOM   13373 O  OE2   . GLU D 2 429 ? 404.577 391.890 204.018 1.00 124.79 ? 429 GLU D OE2   1 
ATOM   13374 N  N     . LYS D 2 430 ? 405.806 391.860 198.576 1.00 117.27 ? 430 LYS D N     1 
ATOM   13375 C  CA    . LYS D 2 430 ? 406.464 392.742 197.613 1.00 117.54 ? 430 LYS D CA    1 
ATOM   13376 C  C     . LYS D 2 430 ? 406.258 392.253 196.184 1.00 118.85 ? 430 LYS D C     1 
ATOM   13377 O  O     . LYS D 2 430 ? 406.004 393.058 195.282 1.00 118.57 ? 430 LYS D O     1 
ATOM   13378 C  CB    . LYS D 2 430 ? 407.959 392.910 197.911 1.00 116.02 ? 430 LYS D CB    1 
ATOM   13379 C  CG    . LYS D 2 430 ? 408.405 393.482 199.293 1.00 121.66 ? 430 LYS D CG    1 
ATOM   13380 C  CD    . LYS D 2 430 ? 407.399 394.392 200.037 1.00 127.48 ? 430 LYS D CD    1 
ATOM   13381 C  CE    . LYS D 2 430 ? 407.767 394.551 201.507 1.00 128.26 ? 430 LYS D CE    1 
ATOM   13382 N  NZ    . LYS D 2 430 ? 407.193 393.475 202.370 1.00 124.99 ? 430 LYS D NZ    1 
ATOM   13383 N  N     . ASP D 2 431 ? 406.342 390.938 195.959 1.00 118.31 ? 431 ASP D N     1 
ATOM   13384 C  CA    . ASP D 2 431 ? 406.083 390.400 194.625 1.00 116.35 ? 431 ASP D CA    1 
ATOM   13385 C  C     . ASP D 2 431 ? 404.641 390.649 194.198 1.00 115.30 ? 431 ASP D C     1 
ATOM   13386 O  O     . ASP D 2 431 ? 404.373 390.940 193.025 1.00 121.24 ? 431 ASP D O     1 
ATOM   13387 C  CB    . ASP D 2 431 ? 406.391 388.903 194.590 1.00 120.48 ? 431 ASP D CB    1 
ATOM   13388 C  CG    . ASP D 2 431 ? 407.847 388.601 194.872 1.00 124.00 ? 431 ASP D CG    1 
ATOM   13389 O  OD1   . ASP D 2 431 ? 408.619 389.556 195.096 1.00 124.08 ? 431 ASP D OD1   1 
ATOM   13390 O  OD2   . ASP D 2 431 ? 408.220 387.410 194.872 1.00 122.07 ? 431 ASP D OD2   1 
ATOM   13391 N  N     . TYR D 2 432 ? 403.699 390.521 195.133 1.00 111.33 ? 432 TYR D N     1 
ATOM   13392 C  CA    . TYR D 2 432 ? 402.291 390.732 194.799 1.00 110.23 ? 432 TYR D CA    1 
ATOM   13393 C  C     . TYR D 2 432 ? 402.025 392.178 194.395 1.00 107.80 ? 432 TYR D C     1 
ATOM   13394 O  O     . TYR D 2 432 ? 401.371 392.437 193.376 1.00 108.03 ? 432 TYR D O     1 
ATOM   13395 C  CB    . TYR D 2 432 ? 401.394 390.323 195.968 1.00 109.84 ? 432 TYR D CB    1 
ATOM   13396 C  CG    . TYR D 2 432 ? 400.790 388.952 195.793 1.00 111.00 ? 432 TYR D CG    1 
ATOM   13397 C  CD1   . TYR D 2 432 ? 399.559 388.793 195.176 1.00 110.88 ? 432 TYR D CD1   1 
ATOM   13398 C  CD2   . TYR D 2 432 ? 401.461 387.816 196.216 1.00 112.91 ? 432 TYR D CD2   1 
ATOM   13399 C  CE1   . TYR D 2 432 ? 399.003 387.544 195.004 1.00 108.35 ? 432 TYR D CE1   1 
ATOM   13400 C  CE2   . TYR D 2 432 ? 400.917 386.563 196.042 1.00 113.76 ? 432 TYR D CE2   1 
ATOM   13401 C  CZ    . TYR D 2 432 ? 399.684 386.433 195.440 1.00 112.43 ? 432 TYR D CZ    1 
ATOM   13402 O  OH    . TYR D 2 432 ? 399.129 385.186 195.266 1.00 116.35 ? 432 TYR D OH    1 
ATOM   13403 N  N     . GLU D 2 433 ? 402.526 393.141 195.173 1.00 119.78 ? 433 GLU D N     1 
ATOM   13404 C  CA    . GLU D 2 433 ? 402.336 394.534 194.773 1.00 120.32 ? 433 GLU D CA    1 
ATOM   13405 C  C     . GLU D 2 433 ? 403.139 394.869 193.520 1.00 119.83 ? 433 GLU D C     1 
ATOM   13406 O  O     . GLU D 2 433 ? 402.753 395.768 192.766 1.00 120.54 ? 433 GLU D O     1 
ATOM   13407 C  CB    . GLU D 2 433 ? 402.695 395.486 195.917 1.00 121.56 ? 433 GLU D CB    1 
ATOM   13408 C  CG    . GLU D 2 433 ? 404.146 395.463 196.337 1.00 127.68 ? 433 GLU D CG    1 
ATOM   13409 C  CD    . GLU D 2 433 ? 404.435 396.361 197.526 1.00 130.94 ? 433 GLU D CD    1 
ATOM   13410 O  OE1   . GLU D 2 433 ? 403.482 396.748 198.235 1.00 133.22 ? 433 GLU D OE1   1 
ATOM   13411 O  OE2   . GLU D 2 433 ? 405.622 396.676 197.756 1.00 127.07 ? 433 GLU D OE2   1 
ATOM   13412 N  N     . GLU D 2 434 ? 404.255 394.173 193.285 1.00 113.03 ? 434 GLU D N     1 
ATOM   13413 C  CA    . GLU D 2 434 ? 405.017 394.381 192.059 1.00 111.71 ? 434 GLU D CA    1 
ATOM   13414 C  C     . GLU D 2 434 ? 404.202 393.979 190.837 1.00 114.05 ? 434 GLU D C     1 
ATOM   13415 O  O     . GLU D 2 434 ? 404.054 394.760 189.890 1.00 113.04 ? 434 GLU D O     1 
ATOM   13416 C  CB    . GLU D 2 434 ? 406.323 393.588 192.125 1.00 112.27 ? 434 GLU D CB    1 
ATOM   13417 C  CG    . GLU D 2 434 ? 407.165 393.631 190.858 1.00 115.63 ? 434 GLU D CG    1 
ATOM   13418 C  CD    . GLU D 2 434 ? 408.578 393.137 191.089 1.00 119.47 ? 434 GLU D CD    1 
ATOM   13419 O  OE1   . GLU D 2 434 ? 409.265 393.687 191.974 1.00 116.85 ? 434 GLU D OE1   1 
ATOM   13420 O  OE2   . GLU D 2 434 ? 409.001 392.196 190.386 1.00 119.30 ? 434 GLU D OE2   1 
ATOM   13421 N  N     . VAL D 2 435 ? 403.660 392.759 190.842 1.00 117.31 ? 435 VAL D N     1 
ATOM   13422 C  CA    . VAL D 2 435 ? 402.859 392.314 189.706 1.00 110.97 ? 435 VAL D CA    1 
ATOM   13423 C  C     . VAL D 2 435 ? 401.538 393.069 189.618 1.00 105.53 ? 435 VAL D C     1 
ATOM   13424 O  O     . VAL D 2 435 ? 400.938 393.125 188.540 1.00 107.66 ? 435 VAL D O     1 
ATOM   13425 C  CB    . VAL D 2 435 ? 402.612 390.788 189.744 1.00 107.80 ? 435 VAL D CB    1 
ATOM   13426 C  CG1   . VAL D 2 435 ? 403.934 390.032 189.710 1.00 102.34 ? 435 VAL D CG1   1 
ATOM   13427 C  CG2   . VAL D 2 435 ? 401.780 390.362 190.956 1.00 110.27 ? 435 VAL D CG2   1 
ATOM   13428 N  N     . GLY D 2 436 ? 401.065 393.658 190.718 1.00 104.17 ? 436 GLY D N     1 
ATOM   13429 C  CA    . GLY D 2 436 ? 399.833 394.424 190.672 1.00 107.43 ? 436 GLY D CA    1 
ATOM   13430 C  C     . GLY D 2 436 ? 399.931 395.781 190.002 1.00 106.54 ? 436 GLY D C     1 
ATOM   13431 O  O     . GLY D 2 436 ? 398.893 396.417 189.798 1.00 103.55 ? 436 GLY D O     1 
ATOM   13432 N  N     . VAL D 2 437 ? 401.135 396.241 189.650 1.00 115.30 ? 437 VAL D N     1 
ATOM   13433 C  CA    . VAL D 2 437 ? 401.346 397.545 189.026 1.00 117.69 ? 437 VAL D CA    1 
ATOM   13434 C  C     . VAL D 2 437 ? 401.335 397.368 187.515 1.00 115.26 ? 437 VAL D C     1 
ATOM   13435 O  O     . VAL D 2 437 ? 401.846 396.371 186.989 1.00 111.27 ? 437 VAL D O     1 
ATOM   13436 C  CB    . VAL D 2 437 ? 402.665 398.179 189.513 1.00 119.75 ? 437 VAL D CB    1 
ATOM   13437 C  CG1   . VAL D 2 437 ? 403.059 399.385 188.662 1.00 117.04 ? 437 VAL D CG1   1 
ATOM   13438 C  CG2   . VAL D 2 437 ? 402.541 398.602 190.970 1.00 113.40 ? 437 VAL D CG2   1 
ATOM   13439 N  N     . ASP D 2 438 ? 400.752 398.338 186.814 1.00 122.20 ? 438 ASP D N     1 
ATOM   13440 C  CA    . ASP D 2 438 ? 400.635 398.267 185.368 1.00 123.56 ? 438 ASP D CA    1 
ATOM   13441 C  C     . ASP D 2 438 ? 402.010 398.369 184.710 1.00 124.61 ? 438 ASP D C     1 
ATOM   13442 O  O     . ASP D 2 438 ? 403.001 398.775 185.323 1.00 119.81 ? 438 ASP D O     1 
ATOM   13443 C  CB    . ASP D 2 438 ? 399.720 399.376 184.852 1.00 118.45 ? 438 ASP D CB    1 
ATOM   13444 N  N     . SER D 2 439 ? 402.057 397.989 183.436 1.00 135.51 ? 439 SER D N     1 
ATOM   13445 C  CA    . SER D 2 439 ? 403.305 397.989 182.692 1.00 133.39 ? 439 SER D CA    1 
ATOM   13446 C  C     . SER D 2 439 ? 403.742 399.414 182.366 1.00 135.08 ? 439 SER D C     1 
ATOM   13447 O  O     . SER D 2 439 ? 402.937 400.348 182.314 1.00 133.69 ? 439 SER D O     1 
ATOM   13448 C  CB    . SER D 2 439 ? 403.158 397.181 181.403 1.00 128.66 ? 439 SER D CB    1 
ATOM   13449 N  N     . VAL D 2 440 ? 405.048 399.570 182.141 1.00 147.38 ? 440 VAL D N     1 
ATOM   13450 C  CA    . VAL D 2 440 ? 405.603 400.883 181.831 1.00 147.84 ? 440 VAL D CA    1 
ATOM   13451 C  C     . VAL D 2 440 ? 405.267 401.341 180.417 1.00 149.85 ? 440 VAL D C     1 
ATOM   13452 O  O     . VAL D 2 440 ? 405.256 402.551 180.156 1.00 144.56 ? 440 VAL D O     1 
ATOM   13453 C  CB    . VAL D 2 440 ? 407.129 400.882 182.019 1.00 142.42 ? 440 VAL D CB    1 
ATOM   13454 N  N     . GLU D 2 441 ? 404.998 400.418 179.498 1.00 153.36 ? 441 GLU D N     1 
ATOM   13455 C  CA    . GLU D 2 441 ? 404.679 400.775 178.120 1.00 149.08 ? 441 GLU D CA    1 
ATOM   13456 C  C     . GLU D 2 441 ? 403.900 399.656 177.440 1.00 147.06 ? 441 GLU D C     1 
ATOM   13457 O  O     . GLU D 2 441 ? 403.938 398.506 177.877 1.00 145.39 ? 441 GLU D O     1 
ATOM   13458 C  CB    . GLU D 2 441 ? 405.957 401.079 177.336 1.00 142.87 ? 441 GLU D CB    1 
HETATM 13459 P  PB    . GDP E 3 .   ? 396.164 368.951 334.963 1.00 79.92  ? 501 GDP B PB    1 
HETATM 13460 O  O1B   . GDP E 3 .   ? 396.142 368.264 333.624 1.00 79.92  ? 501 GDP B O1B   1 
HETATM 13461 O  O2B   . GDP E 3 .   ? 395.633 368.026 336.030 1.00 79.92  ? 501 GDP B O2B   1 
HETATM 13462 O  O3B   . GDP E 3 .   ? 397.588 369.308 335.305 1.00 79.92  ? 501 GDP B O3B   1 
HETATM 13463 O  O3A   . GDP E 3 .   ? 395.287 370.298 334.919 1.00 79.92  ? 501 GDP B O3A   1 
HETATM 13464 P  PA    . GDP E 3 .   ? 394.064 370.505 333.891 1.00 79.92  ? 501 GDP B PA    1 
HETATM 13465 O  O1A   . GDP E 3 .   ? 394.366 369.940 332.526 1.00 79.92  ? 501 GDP B O1A   1 
HETATM 13466 O  O2A   . GDP E 3 .   ? 392.796 369.904 334.443 1.00 79.92  ? 501 GDP B O2A   1 
HETATM 13467 O  "O5'" . GDP E 3 .   ? 393.929 372.103 333.803 1.00 79.92  ? 501 GDP B "O5'" 1 
HETATM 13468 C  "C5'" . GDP E 3 .   ? 392.756 372.740 334.297 1.00 79.92  ? 501 GDP B "C5'" 1 
HETATM 13469 C  "C4'" . GDP E 3 .   ? 392.159 373.620 333.214 1.00 79.92  ? 501 GDP B "C4'" 1 
HETATM 13470 O  "O4'" . GDP E 3 .   ? 391.545 372.779 332.239 1.00 79.92  ? 501 GDP B "O4'" 1 
HETATM 13471 C  "C3'" . GDP E 3 .   ? 391.079 374.524 333.779 1.00 79.92  ? 501 GDP B "C3'" 1 
HETATM 13472 O  "O3'" . GDP E 3 .   ? 391.460 375.892 333.616 1.00 79.92  ? 501 GDP B "O3'" 1 
HETATM 13473 C  "C2'" . GDP E 3 .   ? 389.826 374.237 332.979 1.00 79.92  ? 501 GDP B "C2'" 1 
HETATM 13474 O  "O2'" . GDP E 3 .   ? 389.348 375.441 332.376 1.00 79.92  ? 501 GDP B "O2'" 1 
HETATM 13475 C  "C1'" . GDP E 3 .   ? 390.237 373.246 331.905 1.00 79.92  ? 501 GDP B "C1'" 1 
HETATM 13476 N  N9    . GDP E 3 .   ? 389.299 372.099 331.866 1.00 79.92  ? 501 GDP B N9    1 
HETATM 13477 C  C8    . GDP E 3 .   ? 389.173 371.150 332.811 1.00 79.92  ? 501 GDP B C8    1 
HETATM 13478 N  N7    . GDP E 3 .   ? 388.233 370.236 332.461 1.00 79.92  ? 501 GDP B N7    1 
HETATM 13479 C  C5    . GDP E 3 .   ? 387.743 370.599 331.264 1.00 79.92  ? 501 GDP B C5    1 
HETATM 13480 C  C6    . GDP E 3 .   ? 386.728 370.079 330.322 1.00 79.92  ? 501 GDP B C6    1 
HETATM 13481 O  O6    . GDP E 3 .   ? 386.080 369.044 330.579 1.00 79.92  ? 501 GDP B O6    1 
HETATM 13482 N  N1    . GDP E 3 .   ? 386.518 370.753 329.187 1.00 79.92  ? 501 GDP B N1    1 
HETATM 13483 C  C2    . GDP E 3 .   ? 387.197 371.873 328.883 1.00 79.92  ? 501 GDP B C2    1 
HETATM 13484 N  N2    . GDP E 3 .   ? 386.927 372.496 327.712 1.00 79.92  ? 501 GDP B N2    1 
HETATM 13485 N  N3    . GDP E 3 .   ? 388.142 372.406 329.697 1.00 79.92  ? 501 GDP B N3    1 
HETATM 13486 C  C4    . GDP E 3 .   ? 388.451 371.825 330.877 1.00 79.92  ? 501 GDP B C4    1 
HETATM 13487 P  PB    . GDP F 3 .   ? 395.619 369.770 254.436 1.00 71.15  ? 501 GDP E PB    1 
HETATM 13488 O  O1B   . GDP F 3 .   ? 395.647 369.119 253.077 1.00 71.15  ? 501 GDP E O1B   1 
HETATM 13489 O  O2B   . GDP F 3 .   ? 395.067 368.804 255.454 1.00 71.15  ? 501 GDP E O2B   1 
HETATM 13490 O  O3B   . GDP F 3 .   ? 397.025 370.137 254.843 1.00 71.15  ? 501 GDP E O3B   1 
HETATM 13491 O  O3A   . GDP F 3 .   ? 394.724 371.107 254.418 1.00 71.15  ? 501 GDP E O3A   1 
HETATM 13492 P  PA    . GDP F 3 .   ? 393.502 371.313 253.392 1.00 71.15  ? 501 GDP E PA    1 
HETATM 13493 O  O1A   . GDP F 3 .   ? 393.833 370.787 252.018 1.00 71.15  ? 501 GDP E O1A   1 
HETATM 13494 O  O2A   . GDP F 3 .   ? 392.245 370.671 253.924 1.00 71.15  ? 501 GDP E O2A   1 
HETATM 13495 O  "O5'" . GDP F 3 .   ? 393.330 372.909 253.341 1.00 71.15  ? 501 GDP E "O5'" 1 
HETATM 13496 C  "C5'" . GDP F 3 .   ? 392.096 373.500 253.735 1.00 71.15  ? 501 GDP E "C5'" 1 
HETATM 13497 C  "C4'" . GDP F 3 .   ? 391.492 374.250 252.559 1.00 71.15  ? 501 GDP E "C4'" 1 
HETATM 13498 O  "O4'" . GDP F 3 .   ? 390.895 373.304 251.674 1.00 71.15  ? 501 GDP E "O4'" 1 
HETATM 13499 C  "C3'" . GDP F 3 .   ? 390.393 375.193 253.010 1.00 71.15  ? 501 GDP E "C3'" 1 
HETATM 13500 O  "O3'" . GDP F 3 .   ? 390.731 376.529 252.632 1.00 71.15  ? 501 GDP E "O3'" 1 
HETATM 13501 C  "C2'" . GDP F 3 .   ? 389.139 374.767 252.277 1.00 71.15  ? 501 GDP E "C2'" 1 
HETATM 13502 O  "O2'" . GDP F 3 .   ? 388.556 375.890 251.612 1.00 71.15  ? 501 GDP E "O2'" 1 
HETATM 13503 C  "C1'" . GDP F 3 .   ? 389.601 373.743 251.257 1.00 71.15  ? 501 GDP E "C1'" 1 
HETATM 13504 N  N9    . GDP F 3 .   ? 388.665 372.595 251.188 1.00 71.15  ? 501 GDP E N9    1 
HETATM 13505 C  C8    . GDP F 3 .   ? 388.573 371.590 252.077 1.00 71.15  ? 501 GDP E C8    1 
HETATM 13506 N  N7    . GDP F 3 .   ? 387.622 370.696 251.706 1.00 71.15  ? 501 GDP E N7    1 
HETATM 13507 C  C5    . GDP F 3 .   ? 387.090 371.129 250.550 1.00 71.15  ? 501 GDP E C5    1 
HETATM 13508 C  C6    . GDP F 3 .   ? 386.043 370.664 249.615 1.00 71.15  ? 501 GDP E C6    1 
HETATM 13509 O  O6    . GDP F 3 .   ? 385.406 369.613 249.831 1.00 71.15  ? 501 GDP E O6    1 
HETATM 13510 N  N1    . GDP F 3 .   ? 385.795 371.405 248.529 1.00 71.15  ? 501 GDP E N1    1 
HETATM 13511 C  C2    . GDP F 3 .   ? 386.462 372.543 248.269 1.00 71.15  ? 501 GDP E C2    1 
HETATM 13512 N  N2    . GDP F 3 .   ? 386.152 373.236 247.148 1.00 71.15  ? 501 GDP E N2    1 
HETATM 13513 N  N3    . GDP F 3 .   ? 387.434 373.028 249.082 1.00 71.15  ? 501 GDP E N3    1 
HETATM 13514 C  C4    . GDP F 3 .   ? 387.784 372.377 250.213 1.00 71.15  ? 501 GDP E C4    1 
HETATM 13515 P  PG    . GTP G 4 .   ? 396.674 368.978 295.946 1.00 112.64 ? 501 GTP A PG    1 
HETATM 13516 O  O1G   . GTP G 4 .   ? 396.060 367.637 296.268 1.00 101.32 ? 501 GTP A O1G   1 
HETATM 13517 O  O2G   . GTP G 4 .   ? 398.065 369.061 296.522 1.00 102.53 ? 501 GTP A O2G   1 
HETATM 13518 O  O3G   . GTP G 4 .   ? 395.808 370.082 296.496 1.00 115.45 ? 501 GTP A O3G   1 
HETATM 13519 O  O3B   . GTP G 4 .   ? 396.735 369.134 294.351 1.00 101.09 ? 501 GTP A O3B   1 
HETATM 13520 P  PB    . GTP G 4 .   ? 395.357 369.097 293.534 1.00 108.16 ? 501 GTP A PB    1 
HETATM 13521 O  O1B   . GTP G 4 .   ? 395.673 369.245 292.068 1.00 104.41 ? 501 GTP A O1B   1 
HETATM 13522 O  O2B   . GTP G 4 .   ? 394.584 367.836 293.825 1.00 100.72 ? 501 GTP A O2B   1 
HETATM 13523 O  O3A   . GTP G 4 .   ? 394.586 370.397 294.083 1.00 106.37 ? 501 GTP A O3A   1 
HETATM 13524 P  PA    . GTP G 4 .   ? 393.386 371.094 293.272 1.00 119.95 ? 501 GTP A PA    1 
HETATM 13525 O  O1A   . GTP G 4 .   ? 393.449 370.740 291.809 1.00 109.81 ? 501 GTP A O1A   1 
HETATM 13526 O  O2A   . GTP G 4 .   ? 392.056 370.705 293.866 1.00 109.10 ? 501 GTP A O2A   1 
HETATM 13527 O  "O5'" . GTP G 4 .   ? 393.645 372.670 293.459 1.00 116.54 ? 501 GTP A "O5'" 1 
HETATM 13528 C  "C5'" . GTP G 4 .   ? 392.592 373.537 293.817 1.00 108.65 ? 501 GTP A "C5'" 1 
HETATM 13529 C  "C4'" . GTP G 4 .   ? 391.892 374.076 292.577 1.00 99.39  ? 501 GTP A "C4'" 1 
HETATM 13530 O  "O4'" . GTP G 4 .   ? 391.444 373.014 291.764 1.00 103.46 ? 501 GTP A "O4'" 1 
HETATM 13531 C  "C3'" . GTP G 4 .   ? 390.656 374.875 292.941 1.00 104.64 ? 501 GTP A "C3'" 1 
HETATM 13532 O  "O3'" . GTP G 4 .   ? 390.923 376.252 292.830 1.00 108.08 ? 501 GTP A "O3'" 1 
HETATM 13533 C  "C2'" . GTP G 4 .   ? 389.603 374.468 291.933 1.00 101.01 ? 501 GTP A "C2'" 1 
HETATM 13534 O  "O2'" . GTP G 4 .   ? 389.277 375.557 291.104 1.00 105.40 ? 501 GTP A "O2'" 1 
HETATM 13535 C  "C1'" . GTP G 4 .   ? 390.241 373.363 291.111 1.00 104.45 ? 501 GTP A "C1'" 1 
HETATM 13536 N  N9    . GTP G 4 .   ? 389.350 372.194 291.023 1.00 101.55 ? 501 GTP A N9    1 
HETATM 13537 C  C8    . GTP G 4 .   ? 389.375 371.084 291.823 1.00 102.25 ? 501 GTP A C8    1 
HETATM 13538 N  N7    . GTP G 4 .   ? 388.409 370.235 291.405 1.00 107.20 ? 501 GTP A N7    1 
HETATM 13539 C  C5    . GTP G 4 .   ? 387.781 370.775 290.340 1.00 103.13 ? 501 GTP A C5    1 
HETATM 13540 C  C6    . GTP G 4 .   ? 386.736 370.332 289.538 1.00 103.93 ? 501 GTP A C6    1 
HETATM 13541 O  O6    . GTP G 4 .   ? 386.205 369.246 289.756 1.00 105.72 ? 501 GTP A O6    1 
HETATM 13542 N  N1    . GTP G 4 .   ? 386.286 371.123 288.504 1.00 101.86 ? 501 GTP A N1    1 
HETATM 13543 C  C2    . GTP G 4 .   ? 386.881 372.343 288.268 1.00 100.78 ? 501 GTP A C2    1 
HETATM 13544 N  N2    . GTP G 4 .   ? 386.454 373.105 287.268 1.00 103.91 ? 501 GTP A N2    1 
HETATM 13545 N  N3    . GTP G 4 .   ? 387.917 372.776 289.068 1.00 98.52  ? 501 GTP A N3    1 
HETATM 13546 C  C4    . GTP G 4 .   ? 388.362 372.008 290.090 1.00 100.22 ? 501 GTP A C4    1 
HETATM 13547 MG MG    . MG  H 5 .   ? 394.218 367.137 295.658 1.00 89.58  ? 502 MG  A MG    1 
HETATM 13548 P  PG    . GTP I 4 .   ? 396.131 369.746 215.274 1.00 122.74 ? 501 GTP D PG    1 
HETATM 13549 O  O1G   . GTP I 4 .   ? 394.761 369.425 215.814 1.00 118.20 ? 501 GTP D O1G   1 
HETATM 13550 O  O2G   . GTP I 4 .   ? 397.128 368.694 215.690 1.00 114.12 ? 501 GTP D O2G   1 
HETATM 13551 O  O3G   . GTP I 4 .   ? 396.601 371.090 215.763 1.00 114.02 ? 501 GTP D O3G   1 
HETATM 13552 O  O3B   . GTP I 4 .   ? 396.052 369.791 213.674 1.00 112.47 ? 501 GTP D O3B   1 
HETATM 13553 P  PB    . GTP I 4 .   ? 394.622 369.897 212.960 1.00 116.49 ? 501 GTP D PB    1 
HETATM 13554 O  O1B   . GTP I 4 .   ? 394.850 369.993 211.473 1.00 115.42 ? 501 GTP D O1B   1 
HETATM 13555 O  O2B   . GTP I 4 .   ? 393.764 368.710 213.319 1.00 109.69 ? 501 GTP D O2B   1 
HETATM 13556 O  O3A   . GTP I 4 .   ? 394.005 371.270 213.527 1.00 114.55 ? 501 GTP D O3A   1 
HETATM 13557 P  PA    . GTP I 4 .   ? 392.751 371.977 212.811 1.00 123.83 ? 501 GTP D PA    1 
HETATM 13558 O  O1A   . GTP I 4 .   ? 392.640 371.511 211.384 1.00 118.23 ? 501 GTP D O1A   1 
HETATM 13559 O  O2A   . GTP I 4 .   ? 391.484 371.690 213.576 1.00 116.31 ? 501 GTP D O2A   1 
HETATM 13560 O  "O5'" . GTP I 4 .   ? 393.079 373.551 212.833 1.00 123.16 ? 501 GTP D "O5'" 1 
HETATM 13561 C  "C5'" . GTP I 4 .   ? 392.094 374.476 213.235 1.00 117.18 ? 501 GTP D "C5'" 1 
HETATM 13562 C  "C4'" . GTP I 4 .   ? 391.278 374.980 212.050 1.00 109.20 ? 501 GTP D "C4'" 1 
HETATM 13563 O  "O4'" . GTP I 4 .   ? 390.840 373.916 211.235 1.00 111.39 ? 501 GTP D "O4'" 1 
HETATM 13564 C  "C3'" . GTP I 4 .   ? 390.019 375.674 212.531 1.00 114.32 ? 501 GTP D "C3'" 1 
HETATM 13565 O  "O3'" . GTP I 4 .   ? 390.168 377.069 212.423 1.00 114.43 ? 501 GTP D "O3'" 1 
HETATM 13566 C  "C2'" . GTP I 4 .   ? 388.905 375.202 211.621 1.00 112.23 ? 501 GTP D "C2'" 1 
HETATM 13567 O  "O2'" . GTP I 4 .   ? 388.391 376.286 210.885 1.00 110.57 ? 501 GTP D "O2'" 1 
HETATM 13568 C  "C1'" . GTP I 4 .   ? 389.563 374.201 210.690 1.00 112.72 ? 501 GTP D "C1'" 1 
HETATM 13569 N  N9    . GTP I 4 .   ? 388.791 372.954 210.585 1.00 111.81 ? 501 GTP D N9    1 
HETATM 13570 C  C8    . GTP I 4 .   ? 388.903 371.858 211.398 1.00 111.08 ? 501 GTP D C8    1 
HETATM 13571 N  N7    . GTP I 4 .   ? 388.047 370.910 210.958 1.00 114.98 ? 501 GTP D N7    1 
HETATM 13572 C  C5    . GTP I 4 .   ? 387.391 371.382 209.876 1.00 113.45 ? 501 GTP D C5    1 
HETATM 13573 C  C6    . GTP I 4 .   ? 386.441 370.813 209.042 1.00 112.99 ? 501 GTP D C6    1 
HETATM 13574 O  O6    . GTP I 4 .   ? 386.021 369.681 209.274 1.00 117.82 ? 501 GTP D O6    1 
HETATM 13575 N  N1    . GTP I 4 .   ? 385.932 371.533 207.988 1.00 105.84 ? 501 GTP D N1    1 
HETATM 13576 C  C2    . GTP I 4 .   ? 386.405 372.805 207.757 1.00 108.05 ? 501 GTP D C2    1 
HETATM 13577 N  N2    . GTP I 4 .   ? 385.933 373.507 206.735 1.00 114.26 ? 501 GTP D N2    1 
HETATM 13578 N  N3    . GTP I 4 .   ? 387.363 373.358 208.582 1.00 108.32 ? 501 GTP D N3    1 
HETATM 13579 C  C4    . GTP I 4 .   ? 387.857 372.660 209.623 1.00 109.56 ? 501 GTP D C4    1 
HETATM 13580 MG MG    . MG  J 5 .   ? 394.400 367.692 214.949 1.00 89.38  ? 502 MG  D MG    1 
# 
