data_8V2B
# 
_entry.id   8V2B 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.399 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8V2B         pdb_00008v2b 10.2210/pdb8v2b/pdb 
WWPDB D_1000278770 ?            ?                   
EMDB  EMD-42904    ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2024-11-20 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8V2B 
_pdbx_database_status.recvd_initial_deposition_date   2023-11-22 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        
'Cryo-EM structure of mouse type II OSM receptor complex: model for full extracellular assembly' 
_pdbx_database_related.db_id          EMD-42904 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              matthew.franklin@regeneron.com 
_pdbx_contact_author.name_first         Matthew 
_pdbx_contact_author.name_last          Franklin 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-1482-0136 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Zhou, Y.'       1 ? 
'Franklin, M.C.' 2 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Nat Commun' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2041-1723 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            15 
_citation.language                  ? 
_citation.page_first                9776 
_citation.page_last                 9776 
_citation.title                     
'Structures of complete extracellular assemblies of type I and type II Oncostatin M receptor complexes.' 
_citation.year                      2024 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1038/s41467-024-54124-1 
_citation.pdbx_database_id_PubMed   39532904 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Zhou, Y.'       1 0000-0002-1650-4591 
primary 'Stevis, P.E.'   2 ?                   
primary 'Cao, J.'        3 ?                   
primary 'Ehrlich, G.'    4 ?                   
primary 'Jones, J.'      5 ?                   
primary 'Rafique, A.'    6 0000-0003-4078-7242 
primary 'Sleeman, M.W.'  7 ?                   
primary 'Olson, W.C.'    8 ?                   
primary 'Franklin, M.C.' 9 0000-0002-1482-0136 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man Oncostatin-M                                                                              20645.201 1  ? ? ? ? 
2 polymer     man 'Interleukin-6 receptor subunit beta'                                                     70033.594 1  ? ? ? ? 
3 polymer     man 'Oncostatin-M-specific receptor subunit beta'                                             82357.742 1  ? ? ? ? 
4 branched    man '2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose' 424.401   11 ? ? ? ? 
5 non-polymer man 2-acetamido-2-deoxy-beta-D-glucopyranose                                                  221.208   7  ? ? ? ? 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;ANRGCSNSSSQLLSQLQNQANLTGNTESLLEPYIRLQNLNTPDLRAACTQHSVAFPSEDTLRQLSKPHFLSTVYTTLDRV
LYQLDALRQKFLKTPAFPKLDSARHNILGIRNNVFCMARLLNHSLEIPEPTQTDSGASRSTTTPDVFNTKIGSCGFLWGY
HRFMGSVGRVFREWDDGSTRSRR
;
;ANRGCSNSSSQLLSQLQNQANLTGNTESLLEPYIRLQNLNTPDLRAACTQHSVAFPSEDTLRQLSKPHFLSTVYTTLDRV
LYQLDALRQKFLKTPAFPKLDSARHNILGIRNNVFCMARLLNHSLEIPEPTQTDSGASRSTTTPDVFNTKIGSCGFLWGY
HRFMGSVGRVFREWDDGSTRSRR
;
A ? 
2 'polypeptide(L)' no no 
;QLLEPCGYIYPEFPVVQRGSNFTAICVLKEACLQHYYVNASYIVWKTNHAAVPREQVTVINRTTSSVTFTDVVLPSVQLT
CNILSFGQIEQNVYGVTMLSGFPPDKPTNLTCIVNEGKNMLCQWDPGRETYLETNYTLKSEWATEKFPDCQSKHGTSCMV
SYMPTYYVNIEVWVEAENALGKVSSESINFDPVDKVKPTPPYNLSVTNSEELSSILKLSWVSSGLGGLLDLKSDIQYRTK
DASTWIQVPLEDTMSPRTSFTVQDLKPFTEYVFRIRSIKDSGKGYWSDWSEEASGTTYEDRPSRPPSFWYKTNPSHGQEY
RSVRLIWKALPLSEANGKILDYEVILTQSKSVSQTYTVTGTELTVNLTNDRYVASLAARNKVGKSAAAVLTIPSPHVTAA
YSVVNLKAFPKDNLLWVEWTPPPKPVSKYILEWCVLSENAPCVEDWQQEDATVNRTHLRGRLLESKCYQITVTPVFATGP
GGSESLKAYLKQAAPARGPTVRTKKVGKNEAVLAWDQIPVDDQNGFIRNYSISYRTSVGKEMVVHVDSSHTEYTLSSLSS
DTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEEQKLISEEDLGGEQKLISEEDLHHHHHH
;
;QLLEPCGYIYPEFPVVQRGSNFTAICVLKEACLQHYYVNASYIVWKTNHAAVPREQVTVINRTTSSVTFTDVVLPSVQLT
CNILSFGQIEQNVYGVTMLSGFPPDKPTNLTCIVNEGKNMLCQWDPGRETYLETNYTLKSEWATEKFPDCQSKHGTSCMV
SYMPTYYVNIEVWVEAENALGKVSSESINFDPVDKVKPTPPYNLSVTNSEELSSILKLSWVSSGLGGLLDLKSDIQYRTK
DASTWIQVPLEDTMSPRTSFTVQDLKPFTEYVFRIRSIKDSGKGYWSDWSEEASGTTYEDRPSRPPSFWYKTNPSHGQEY
RSVRLIWKALPLSEANGKILDYEVILTQSKSVSQTYTVTGTELTVNLTNDRYVASLAARNKVGKSAAAVLTIPSPHVTAA
YSVVNLKAFPKDNLLWVEWTPPPKPVSKYILEWCVLSENAPCVEDWQQEDATVNRTHLRGRLLESKCYQITVTPVFATGP
GGSESLKAYLKQAAPARGPTVRTKKVGKNEAVLAWDQIPVDDQNGFIRNYSISYRTSVGKEMVVHVDSSHTEYTLSSLSS
DTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEEQKLISEEDLGGEQKLISEEDLHHHHHH
;
B ? 
3 'polypeptide(L)' no no 
;EVLEEPLPLTPEIHKVSFQLKLQEVNLEWTVPALTHEELNMIFQIEISRLNISNTIWVENYSTTVKREEAVRWNWTSDIP
LECVKHFIRIRALVDDTKSLPQSSWGNWSSWKEVNAKVSVEPDKSLIFPKDKVLEEGSNVTICLMYGQNVYNVSCKLQDE
PIHGEQLDSHVSLLKLNNVVFLSDTGTNINCQATKGPKRIFGTVLFVSKVLEEPKNVSCETRDFKTLDCSWEPGVDTTLT
WRKQRFQNYTLCESFSKRCEVSNYRNSYTWQITEGSQEMYNFTLTAENQLRKRSVNINFNLTHRVHPKAPQDVTLKIIGA
TKANMTWKVHSHGNNYTLLCQVKLQYGEVIHEHNVSVHMSANYLFSDLDPDTKYKAFVRCASANHFWKWSDWTQKEFSTP
ETAPSQALDVWRQVWSENGRRIVTLFWKPLLKSQANGKIISYNIVVENEAKPTESEHYCVWAPALSTNLSLDLQPYKIRI
TTNNSMGASPESLMVLSNDSGHEEVKEKTIKGIKDAFNISWEPVSGDTMGYVVDWCAHSQDQRCDLQWKNLGPNTTSTTI
TSDDFKPGVRYNFRIFERSVEHKARLVEKQRGYTQELAPLVNPKVEIPYSTPNSFVLRWPDYDSDFQAGFIKGYLVYVKS
KEMQCNQPWERTLLPDNSVLCKYDINGSETKTLTVENLQPESLYEFFVTPYTSAGPGPNETFTKVTTPDARSHML
;
;EVLEEPLPLTPEIHKVSFQLKLQEVNLEWTVPALTHEELNMIFQIEISRLNISNTIWVENYSTTVKREEAVRWNWTSDIP
LECVKHFIRIRALVDDTKSLPQSSWGNWSSWKEVNAKVSVEPDKSLIFPKDKVLEEGSNVTICLMYGQNVYNVSCKLQDE
PIHGEQLDSHVSLLKLNNVVFLSDTGTNINCQATKGPKRIFGTVLFVSKVLEEPKNVSCETRDFKTLDCSWEPGVDTTLT
WRKQRFQNYTLCESFSKRCEVSNYRNSYTWQITEGSQEMYNFTLTAENQLRKRSVNINFNLTHRVHPKAPQDVTLKIIGA
TKANMTWKVHSHGNNYTLLCQVKLQYGEVIHEHNVSVHMSANYLFSDLDPDTKYKAFVRCASANHFWKWSDWTQKEFSTP
ETAPSQALDVWRQVWSENGRRIVTLFWKPLLKSQANGKIISYNIVVENEAKPTESEHYCVWAPALSTNLSLDLQPYKIRI
TTNNSMGASPESLMVLSNDSGHEEVKEKTIKGIKDAFNISWEPVSGDTMGYVVDWCAHSQDQRCDLQWKNLGPNTTSTTI
TSDDFKPGVRYNFRIFERSVEHKARLVEKQRGYTQELAPLVNPKVEIPYSTPNSFVLRWPDYDSDFQAGFIKGYLVYVKS
KEMQCNQPWERTLLPDNSVLCKYDINGSETKTLTVENLQPESLYEFFVTPYTSAGPGPNETFTKVTTPDARSHML
;
C ? 
# 
_pdbx_entity_nonpoly.entity_id   5 
_pdbx_entity_nonpoly.name        2-acetamido-2-deoxy-beta-D-glucopyranose 
_pdbx_entity_nonpoly.comp_id     NAG 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   ALA n 
1 2   ASN n 
1 3   ARG n 
1 4   GLY n 
1 5   CYS n 
1 6   SER n 
1 7   ASN n 
1 8   SER n 
1 9   SER n 
1 10  SER n 
1 11  GLN n 
1 12  LEU n 
1 13  LEU n 
1 14  SER n 
1 15  GLN n 
1 16  LEU n 
1 17  GLN n 
1 18  ASN n 
1 19  GLN n 
1 20  ALA n 
1 21  ASN n 
1 22  LEU n 
1 23  THR n 
1 24  GLY n 
1 25  ASN n 
1 26  THR n 
1 27  GLU n 
1 28  SER n 
1 29  LEU n 
1 30  LEU n 
1 31  GLU n 
1 32  PRO n 
1 33  TYR n 
1 34  ILE n 
1 35  ARG n 
1 36  LEU n 
1 37  GLN n 
1 38  ASN n 
1 39  LEU n 
1 40  ASN n 
1 41  THR n 
1 42  PRO n 
1 43  ASP n 
1 44  LEU n 
1 45  ARG n 
1 46  ALA n 
1 47  ALA n 
1 48  CYS n 
1 49  THR n 
1 50  GLN n 
1 51  HIS n 
1 52  SER n 
1 53  VAL n 
1 54  ALA n 
1 55  PHE n 
1 56  PRO n 
1 57  SER n 
1 58  GLU n 
1 59  ASP n 
1 60  THR n 
1 61  LEU n 
1 62  ARG n 
1 63  GLN n 
1 64  LEU n 
1 65  SER n 
1 66  LYS n 
1 67  PRO n 
1 68  HIS n 
1 69  PHE n 
1 70  LEU n 
1 71  SER n 
1 72  THR n 
1 73  VAL n 
1 74  TYR n 
1 75  THR n 
1 76  THR n 
1 77  LEU n 
1 78  ASP n 
1 79  ARG n 
1 80  VAL n 
1 81  LEU n 
1 82  TYR n 
1 83  GLN n 
1 84  LEU n 
1 85  ASP n 
1 86  ALA n 
1 87  LEU n 
1 88  ARG n 
1 89  GLN n 
1 90  LYS n 
1 91  PHE n 
1 92  LEU n 
1 93  LYS n 
1 94  THR n 
1 95  PRO n 
1 96  ALA n 
1 97  PHE n 
1 98  PRO n 
1 99  LYS n 
1 100 LEU n 
1 101 ASP n 
1 102 SER n 
1 103 ALA n 
1 104 ARG n 
1 105 HIS n 
1 106 ASN n 
1 107 ILE n 
1 108 LEU n 
1 109 GLY n 
1 110 ILE n 
1 111 ARG n 
1 112 ASN n 
1 113 ASN n 
1 114 VAL n 
1 115 PHE n 
1 116 CYS n 
1 117 MET n 
1 118 ALA n 
1 119 ARG n 
1 120 LEU n 
1 121 LEU n 
1 122 ASN n 
1 123 HIS n 
1 124 SER n 
1 125 LEU n 
1 126 GLU n 
1 127 ILE n 
1 128 PRO n 
1 129 GLU n 
1 130 PRO n 
1 131 THR n 
1 132 GLN n 
1 133 THR n 
1 134 ASP n 
1 135 SER n 
1 136 GLY n 
1 137 ALA n 
1 138 SER n 
1 139 ARG n 
1 140 SER n 
1 141 THR n 
1 142 THR n 
1 143 THR n 
1 144 PRO n 
1 145 ASP n 
1 146 VAL n 
1 147 PHE n 
1 148 ASN n 
1 149 THR n 
1 150 LYS n 
1 151 ILE n 
1 152 GLY n 
1 153 SER n 
1 154 CYS n 
1 155 GLY n 
1 156 PHE n 
1 157 LEU n 
1 158 TRP n 
1 159 GLY n 
1 160 TYR n 
1 161 HIS n 
1 162 ARG n 
1 163 PHE n 
1 164 MET n 
1 165 GLY n 
1 166 SER n 
1 167 VAL n 
1 168 GLY n 
1 169 ARG n 
1 170 VAL n 
1 171 PHE n 
1 172 ARG n 
1 173 GLU n 
1 174 TRP n 
1 175 ASP n 
1 176 ASP n 
1 177 GLY n 
1 178 SER n 
1 179 THR n 
1 180 ARG n 
1 181 SER n 
1 182 ARG n 
1 183 ARG n 
2 1   GLN n 
2 2   LEU n 
2 3   LEU n 
2 4   GLU n 
2 5   PRO n 
2 6   CYS n 
2 7   GLY n 
2 8   TYR n 
2 9   ILE n 
2 10  TYR n 
2 11  PRO n 
2 12  GLU n 
2 13  PHE n 
2 14  PRO n 
2 15  VAL n 
2 16  VAL n 
2 17  GLN n 
2 18  ARG n 
2 19  GLY n 
2 20  SER n 
2 21  ASN n 
2 22  PHE n 
2 23  THR n 
2 24  ALA n 
2 25  ILE n 
2 26  CYS n 
2 27  VAL n 
2 28  LEU n 
2 29  LYS n 
2 30  GLU n 
2 31  ALA n 
2 32  CYS n 
2 33  LEU n 
2 34  GLN n 
2 35  HIS n 
2 36  TYR n 
2 37  TYR n 
2 38  VAL n 
2 39  ASN n 
2 40  ALA n 
2 41  SER n 
2 42  TYR n 
2 43  ILE n 
2 44  VAL n 
2 45  TRP n 
2 46  LYS n 
2 47  THR n 
2 48  ASN n 
2 49  HIS n 
2 50  ALA n 
2 51  ALA n 
2 52  VAL n 
2 53  PRO n 
2 54  ARG n 
2 55  GLU n 
2 56  GLN n 
2 57  VAL n 
2 58  THR n 
2 59  VAL n 
2 60  ILE n 
2 61  ASN n 
2 62  ARG n 
2 63  THR n 
2 64  THR n 
2 65  SER n 
2 66  SER n 
2 67  VAL n 
2 68  THR n 
2 69  PHE n 
2 70  THR n 
2 71  ASP n 
2 72  VAL n 
2 73  VAL n 
2 74  LEU n 
2 75  PRO n 
2 76  SER n 
2 77  VAL n 
2 78  GLN n 
2 79  LEU n 
2 80  THR n 
2 81  CYS n 
2 82  ASN n 
2 83  ILE n 
2 84  LEU n 
2 85  SER n 
2 86  PHE n 
2 87  GLY n 
2 88  GLN n 
2 89  ILE n 
2 90  GLU n 
2 91  GLN n 
2 92  ASN n 
2 93  VAL n 
2 94  TYR n 
2 95  GLY n 
2 96  VAL n 
2 97  THR n 
2 98  MET n 
2 99  LEU n 
2 100 SER n 
2 101 GLY n 
2 102 PHE n 
2 103 PRO n 
2 104 PRO n 
2 105 ASP n 
2 106 LYS n 
2 107 PRO n 
2 108 THR n 
2 109 ASN n 
2 110 LEU n 
2 111 THR n 
2 112 CYS n 
2 113 ILE n 
2 114 VAL n 
2 115 ASN n 
2 116 GLU n 
2 117 GLY n 
2 118 LYS n 
2 119 ASN n 
2 120 MET n 
2 121 LEU n 
2 122 CYS n 
2 123 GLN n 
2 124 TRP n 
2 125 ASP n 
2 126 PRO n 
2 127 GLY n 
2 128 ARG n 
2 129 GLU n 
2 130 THR n 
2 131 TYR n 
2 132 LEU n 
2 133 GLU n 
2 134 THR n 
2 135 ASN n 
2 136 TYR n 
2 137 THR n 
2 138 LEU n 
2 139 LYS n 
2 140 SER n 
2 141 GLU n 
2 142 TRP n 
2 143 ALA n 
2 144 THR n 
2 145 GLU n 
2 146 LYS n 
2 147 PHE n 
2 148 PRO n 
2 149 ASP n 
2 150 CYS n 
2 151 GLN n 
2 152 SER n 
2 153 LYS n 
2 154 HIS n 
2 155 GLY n 
2 156 THR n 
2 157 SER n 
2 158 CYS n 
2 159 MET n 
2 160 VAL n 
2 161 SER n 
2 162 TYR n 
2 163 MET n 
2 164 PRO n 
2 165 THR n 
2 166 TYR n 
2 167 TYR n 
2 168 VAL n 
2 169 ASN n 
2 170 ILE n 
2 171 GLU n 
2 172 VAL n 
2 173 TRP n 
2 174 VAL n 
2 175 GLU n 
2 176 ALA n 
2 177 GLU n 
2 178 ASN n 
2 179 ALA n 
2 180 LEU n 
2 181 GLY n 
2 182 LYS n 
2 183 VAL n 
2 184 SER n 
2 185 SER n 
2 186 GLU n 
2 187 SER n 
2 188 ILE n 
2 189 ASN n 
2 190 PHE n 
2 191 ASP n 
2 192 PRO n 
2 193 VAL n 
2 194 ASP n 
2 195 LYS n 
2 196 VAL n 
2 197 LYS n 
2 198 PRO n 
2 199 THR n 
2 200 PRO n 
2 201 PRO n 
2 202 TYR n 
2 203 ASN n 
2 204 LEU n 
2 205 SER n 
2 206 VAL n 
2 207 THR n 
2 208 ASN n 
2 209 SER n 
2 210 GLU n 
2 211 GLU n 
2 212 LEU n 
2 213 SER n 
2 214 SER n 
2 215 ILE n 
2 216 LEU n 
2 217 LYS n 
2 218 LEU n 
2 219 SER n 
2 220 TRP n 
2 221 VAL n 
2 222 SER n 
2 223 SER n 
2 224 GLY n 
2 225 LEU n 
2 226 GLY n 
2 227 GLY n 
2 228 LEU n 
2 229 LEU n 
2 230 ASP n 
2 231 LEU n 
2 232 LYS n 
2 233 SER n 
2 234 ASP n 
2 235 ILE n 
2 236 GLN n 
2 237 TYR n 
2 238 ARG n 
2 239 THR n 
2 240 LYS n 
2 241 ASP n 
2 242 ALA n 
2 243 SER n 
2 244 THR n 
2 245 TRP n 
2 246 ILE n 
2 247 GLN n 
2 248 VAL n 
2 249 PRO n 
2 250 LEU n 
2 251 GLU n 
2 252 ASP n 
2 253 THR n 
2 254 MET n 
2 255 SER n 
2 256 PRO n 
2 257 ARG n 
2 258 THR n 
2 259 SER n 
2 260 PHE n 
2 261 THR n 
2 262 VAL n 
2 263 GLN n 
2 264 ASP n 
2 265 LEU n 
2 266 LYS n 
2 267 PRO n 
2 268 PHE n 
2 269 THR n 
2 270 GLU n 
2 271 TYR n 
2 272 VAL n 
2 273 PHE n 
2 274 ARG n 
2 275 ILE n 
2 276 ARG n 
2 277 SER n 
2 278 ILE n 
2 279 LYS n 
2 280 ASP n 
2 281 SER n 
2 282 GLY n 
2 283 LYS n 
2 284 GLY n 
2 285 TYR n 
2 286 TRP n 
2 287 SER n 
2 288 ASP n 
2 289 TRP n 
2 290 SER n 
2 291 GLU n 
2 292 GLU n 
2 293 ALA n 
2 294 SER n 
2 295 GLY n 
2 296 THR n 
2 297 THR n 
2 298 TYR n 
2 299 GLU n 
2 300 ASP n 
2 301 ARG n 
2 302 PRO n 
2 303 SER n 
2 304 ARG n 
2 305 PRO n 
2 306 PRO n 
2 307 SER n 
2 308 PHE n 
2 309 TRP n 
2 310 TYR n 
2 311 LYS n 
2 312 THR n 
2 313 ASN n 
2 314 PRO n 
2 315 SER n 
2 316 HIS n 
2 317 GLY n 
2 318 GLN n 
2 319 GLU n 
2 320 TYR n 
2 321 ARG n 
2 322 SER n 
2 323 VAL n 
2 324 ARG n 
2 325 LEU n 
2 326 ILE n 
2 327 TRP n 
2 328 LYS n 
2 329 ALA n 
2 330 LEU n 
2 331 PRO n 
2 332 LEU n 
2 333 SER n 
2 334 GLU n 
2 335 ALA n 
2 336 ASN n 
2 337 GLY n 
2 338 LYS n 
2 339 ILE n 
2 340 LEU n 
2 341 ASP n 
2 342 TYR n 
2 343 GLU n 
2 344 VAL n 
2 345 ILE n 
2 346 LEU n 
2 347 THR n 
2 348 GLN n 
2 349 SER n 
2 350 LYS n 
2 351 SER n 
2 352 VAL n 
2 353 SER n 
2 354 GLN n 
2 355 THR n 
2 356 TYR n 
2 357 THR n 
2 358 VAL n 
2 359 THR n 
2 360 GLY n 
2 361 THR n 
2 362 GLU n 
2 363 LEU n 
2 364 THR n 
2 365 VAL n 
2 366 ASN n 
2 367 LEU n 
2 368 THR n 
2 369 ASN n 
2 370 ASP n 
2 371 ARG n 
2 372 TYR n 
2 373 VAL n 
2 374 ALA n 
2 375 SER n 
2 376 LEU n 
2 377 ALA n 
2 378 ALA n 
2 379 ARG n 
2 380 ASN n 
2 381 LYS n 
2 382 VAL n 
2 383 GLY n 
2 384 LYS n 
2 385 SER n 
2 386 ALA n 
2 387 ALA n 
2 388 ALA n 
2 389 VAL n 
2 390 LEU n 
2 391 THR n 
2 392 ILE n 
2 393 PRO n 
2 394 SER n 
2 395 PRO n 
2 396 HIS n 
2 397 VAL n 
2 398 THR n 
2 399 ALA n 
2 400 ALA n 
2 401 TYR n 
2 402 SER n 
2 403 VAL n 
2 404 VAL n 
2 405 ASN n 
2 406 LEU n 
2 407 LYS n 
2 408 ALA n 
2 409 PHE n 
2 410 PRO n 
2 411 LYS n 
2 412 ASP n 
2 413 ASN n 
2 414 LEU n 
2 415 LEU n 
2 416 TRP n 
2 417 VAL n 
2 418 GLU n 
2 419 TRP n 
2 420 THR n 
2 421 PRO n 
2 422 PRO n 
2 423 PRO n 
2 424 LYS n 
2 425 PRO n 
2 426 VAL n 
2 427 SER n 
2 428 LYS n 
2 429 TYR n 
2 430 ILE n 
2 431 LEU n 
2 432 GLU n 
2 433 TRP n 
2 434 CYS n 
2 435 VAL n 
2 436 LEU n 
2 437 SER n 
2 438 GLU n 
2 439 ASN n 
2 440 ALA n 
2 441 PRO n 
2 442 CYS n 
2 443 VAL n 
2 444 GLU n 
2 445 ASP n 
2 446 TRP n 
2 447 GLN n 
2 448 GLN n 
2 449 GLU n 
2 450 ASP n 
2 451 ALA n 
2 452 THR n 
2 453 VAL n 
2 454 ASN n 
2 455 ARG n 
2 456 THR n 
2 457 HIS n 
2 458 LEU n 
2 459 ARG n 
2 460 GLY n 
2 461 ARG n 
2 462 LEU n 
2 463 LEU n 
2 464 GLU n 
2 465 SER n 
2 466 LYS n 
2 467 CYS n 
2 468 TYR n 
2 469 GLN n 
2 470 ILE n 
2 471 THR n 
2 472 VAL n 
2 473 THR n 
2 474 PRO n 
2 475 VAL n 
2 476 PHE n 
2 477 ALA n 
2 478 THR n 
2 479 GLY n 
2 480 PRO n 
2 481 GLY n 
2 482 GLY n 
2 483 SER n 
2 484 GLU n 
2 485 SER n 
2 486 LEU n 
2 487 LYS n 
2 488 ALA n 
2 489 TYR n 
2 490 LEU n 
2 491 LYS n 
2 492 GLN n 
2 493 ALA n 
2 494 ALA n 
2 495 PRO n 
2 496 ALA n 
2 497 ARG n 
2 498 GLY n 
2 499 PRO n 
2 500 THR n 
2 501 VAL n 
2 502 ARG n 
2 503 THR n 
2 504 LYS n 
2 505 LYS n 
2 506 VAL n 
2 507 GLY n 
2 508 LYS n 
2 509 ASN n 
2 510 GLU n 
2 511 ALA n 
2 512 VAL n 
2 513 LEU n 
2 514 ALA n 
2 515 TRP n 
2 516 ASP n 
2 517 GLN n 
2 518 ILE n 
2 519 PRO n 
2 520 VAL n 
2 521 ASP n 
2 522 ASP n 
2 523 GLN n 
2 524 ASN n 
2 525 GLY n 
2 526 PHE n 
2 527 ILE n 
2 528 ARG n 
2 529 ASN n 
2 530 TYR n 
2 531 SER n 
2 532 ILE n 
2 533 SER n 
2 534 TYR n 
2 535 ARG n 
2 536 THR n 
2 537 SER n 
2 538 VAL n 
2 539 GLY n 
2 540 LYS n 
2 541 GLU n 
2 542 MET n 
2 543 VAL n 
2 544 VAL n 
2 545 HIS n 
2 546 VAL n 
2 547 ASP n 
2 548 SER n 
2 549 SER n 
2 550 HIS n 
2 551 THR n 
2 552 GLU n 
2 553 TYR n 
2 554 THR n 
2 555 LEU n 
2 556 SER n 
2 557 SER n 
2 558 LEU n 
2 559 SER n 
2 560 SER n 
2 561 ASP n 
2 562 THR n 
2 563 LEU n 
2 564 TYR n 
2 565 MET n 
2 566 VAL n 
2 567 ARG n 
2 568 MET n 
2 569 ALA n 
2 570 ALA n 
2 571 TYR n 
2 572 THR n 
2 573 ASP n 
2 574 GLU n 
2 575 GLY n 
2 576 GLY n 
2 577 LYS n 
2 578 ASP n 
2 579 GLY n 
2 580 PRO n 
2 581 GLU n 
2 582 PHE n 
2 583 THR n 
2 584 PHE n 
2 585 THR n 
2 586 THR n 
2 587 PRO n 
2 588 LYS n 
2 589 PHE n 
2 590 ALA n 
2 591 GLN n 
2 592 GLY n 
2 593 GLU n 
2 594 ILE n 
2 595 GLU n 
2 596 GLU n 
2 597 GLN n 
2 598 LYS n 
2 599 LEU n 
2 600 ILE n 
2 601 SER n 
2 602 GLU n 
2 603 GLU n 
2 604 ASP n 
2 605 LEU n 
2 606 GLY n 
2 607 GLY n 
2 608 GLU n 
2 609 GLN n 
2 610 LYS n 
2 611 LEU n 
2 612 ILE n 
2 613 SER n 
2 614 GLU n 
2 615 GLU n 
2 616 ASP n 
2 617 LEU n 
2 618 HIS n 
2 619 HIS n 
2 620 HIS n 
2 621 HIS n 
2 622 HIS n 
2 623 HIS n 
3 1   GLU n 
3 2   VAL n 
3 3   LEU n 
3 4   GLU n 
3 5   GLU n 
3 6   PRO n 
3 7   LEU n 
3 8   PRO n 
3 9   LEU n 
3 10  THR n 
3 11  PRO n 
3 12  GLU n 
3 13  ILE n 
3 14  HIS n 
3 15  LYS n 
3 16  VAL n 
3 17  SER n 
3 18  PHE n 
3 19  GLN n 
3 20  LEU n 
3 21  LYS n 
3 22  LEU n 
3 23  GLN n 
3 24  GLU n 
3 25  VAL n 
3 26  ASN n 
3 27  LEU n 
3 28  GLU n 
3 29  TRP n 
3 30  THR n 
3 31  VAL n 
3 32  PRO n 
3 33  ALA n 
3 34  LEU n 
3 35  THR n 
3 36  HIS n 
3 37  GLU n 
3 38  GLU n 
3 39  LEU n 
3 40  ASN n 
3 41  MET n 
3 42  ILE n 
3 43  PHE n 
3 44  GLN n 
3 45  ILE n 
3 46  GLU n 
3 47  ILE n 
3 48  SER n 
3 49  ARG n 
3 50  LEU n 
3 51  ASN n 
3 52  ILE n 
3 53  SER n 
3 54  ASN n 
3 55  THR n 
3 56  ILE n 
3 57  TRP n 
3 58  VAL n 
3 59  GLU n 
3 60  ASN n 
3 61  TYR n 
3 62  SER n 
3 63  THR n 
3 64  THR n 
3 65  VAL n 
3 66  LYS n 
3 67  ARG n 
3 68  GLU n 
3 69  GLU n 
3 70  ALA n 
3 71  VAL n 
3 72  ARG n 
3 73  TRP n 
3 74  ASN n 
3 75  TRP n 
3 76  THR n 
3 77  SER n 
3 78  ASP n 
3 79  ILE n 
3 80  PRO n 
3 81  LEU n 
3 82  GLU n 
3 83  CYS n 
3 84  VAL n 
3 85  LYS n 
3 86  HIS n 
3 87  PHE n 
3 88  ILE n 
3 89  ARG n 
3 90  ILE n 
3 91  ARG n 
3 92  ALA n 
3 93  LEU n 
3 94  VAL n 
3 95  ASP n 
3 96  ASP n 
3 97  THR n 
3 98  LYS n 
3 99  SER n 
3 100 LEU n 
3 101 PRO n 
3 102 GLN n 
3 103 SER n 
3 104 SER n 
3 105 TRP n 
3 106 GLY n 
3 107 ASN n 
3 108 TRP n 
3 109 SER n 
3 110 SER n 
3 111 TRP n 
3 112 LYS n 
3 113 GLU n 
3 114 VAL n 
3 115 ASN n 
3 116 ALA n 
3 117 LYS n 
3 118 VAL n 
3 119 SER n 
3 120 VAL n 
3 121 GLU n 
3 122 PRO n 
3 123 ASP n 
3 124 LYS n 
3 125 SER n 
3 126 LEU n 
3 127 ILE n 
3 128 PHE n 
3 129 PRO n 
3 130 LYS n 
3 131 ASP n 
3 132 LYS n 
3 133 VAL n 
3 134 LEU n 
3 135 GLU n 
3 136 GLU n 
3 137 GLY n 
3 138 SER n 
3 139 ASN n 
3 140 VAL n 
3 141 THR n 
3 142 ILE n 
3 143 CYS n 
3 144 LEU n 
3 145 MET n 
3 146 TYR n 
3 147 GLY n 
3 148 GLN n 
3 149 ASN n 
3 150 VAL n 
3 151 TYR n 
3 152 ASN n 
3 153 VAL n 
3 154 SER n 
3 155 CYS n 
3 156 LYS n 
3 157 LEU n 
3 158 GLN n 
3 159 ASP n 
3 160 GLU n 
3 161 PRO n 
3 162 ILE n 
3 163 HIS n 
3 164 GLY n 
3 165 GLU n 
3 166 GLN n 
3 167 LEU n 
3 168 ASP n 
3 169 SER n 
3 170 HIS n 
3 171 VAL n 
3 172 SER n 
3 173 LEU n 
3 174 LEU n 
3 175 LYS n 
3 176 LEU n 
3 177 ASN n 
3 178 ASN n 
3 179 VAL n 
3 180 VAL n 
3 181 PHE n 
3 182 LEU n 
3 183 SER n 
3 184 ASP n 
3 185 THR n 
3 186 GLY n 
3 187 THR n 
3 188 ASN n 
3 189 ILE n 
3 190 ASN n 
3 191 CYS n 
3 192 GLN n 
3 193 ALA n 
3 194 THR n 
3 195 LYS n 
3 196 GLY n 
3 197 PRO n 
3 198 LYS n 
3 199 ARG n 
3 200 ILE n 
3 201 PHE n 
3 202 GLY n 
3 203 THR n 
3 204 VAL n 
3 205 LEU n 
3 206 PHE n 
3 207 VAL n 
3 208 SER n 
3 209 LYS n 
3 210 VAL n 
3 211 LEU n 
3 212 GLU n 
3 213 GLU n 
3 214 PRO n 
3 215 LYS n 
3 216 ASN n 
3 217 VAL n 
3 218 SER n 
3 219 CYS n 
3 220 GLU n 
3 221 THR n 
3 222 ARG n 
3 223 ASP n 
3 224 PHE n 
3 225 LYS n 
3 226 THR n 
3 227 LEU n 
3 228 ASP n 
3 229 CYS n 
3 230 SER n 
3 231 TRP n 
3 232 GLU n 
3 233 PRO n 
3 234 GLY n 
3 235 VAL n 
3 236 ASP n 
3 237 THR n 
3 238 THR n 
3 239 LEU n 
3 240 THR n 
3 241 TRP n 
3 242 ARG n 
3 243 LYS n 
3 244 GLN n 
3 245 ARG n 
3 246 PHE n 
3 247 GLN n 
3 248 ASN n 
3 249 TYR n 
3 250 THR n 
3 251 LEU n 
3 252 CYS n 
3 253 GLU n 
3 254 SER n 
3 255 PHE n 
3 256 SER n 
3 257 LYS n 
3 258 ARG n 
3 259 CYS n 
3 260 GLU n 
3 261 VAL n 
3 262 SER n 
3 263 ASN n 
3 264 TYR n 
3 265 ARG n 
3 266 ASN n 
3 267 SER n 
3 268 TYR n 
3 269 THR n 
3 270 TRP n 
3 271 GLN n 
3 272 ILE n 
3 273 THR n 
3 274 GLU n 
3 275 GLY n 
3 276 SER n 
3 277 GLN n 
3 278 GLU n 
3 279 MET n 
3 280 TYR n 
3 281 ASN n 
3 282 PHE n 
3 283 THR n 
3 284 LEU n 
3 285 THR n 
3 286 ALA n 
3 287 GLU n 
3 288 ASN n 
3 289 GLN n 
3 290 LEU n 
3 291 ARG n 
3 292 LYS n 
3 293 ARG n 
3 294 SER n 
3 295 VAL n 
3 296 ASN n 
3 297 ILE n 
3 298 ASN n 
3 299 PHE n 
3 300 ASN n 
3 301 LEU n 
3 302 THR n 
3 303 HIS n 
3 304 ARG n 
3 305 VAL n 
3 306 HIS n 
3 307 PRO n 
3 308 LYS n 
3 309 ALA n 
3 310 PRO n 
3 311 GLN n 
3 312 ASP n 
3 313 VAL n 
3 314 THR n 
3 315 LEU n 
3 316 LYS n 
3 317 ILE n 
3 318 ILE n 
3 319 GLY n 
3 320 ALA n 
3 321 THR n 
3 322 LYS n 
3 323 ALA n 
3 324 ASN n 
3 325 MET n 
3 326 THR n 
3 327 TRP n 
3 328 LYS n 
3 329 VAL n 
3 330 HIS n 
3 331 SER n 
3 332 HIS n 
3 333 GLY n 
3 334 ASN n 
3 335 ASN n 
3 336 TYR n 
3 337 THR n 
3 338 LEU n 
3 339 LEU n 
3 340 CYS n 
3 341 GLN n 
3 342 VAL n 
3 343 LYS n 
3 344 LEU n 
3 345 GLN n 
3 346 TYR n 
3 347 GLY n 
3 348 GLU n 
3 349 VAL n 
3 350 ILE n 
3 351 HIS n 
3 352 GLU n 
3 353 HIS n 
3 354 ASN n 
3 355 VAL n 
3 356 SER n 
3 357 VAL n 
3 358 HIS n 
3 359 MET n 
3 360 SER n 
3 361 ALA n 
3 362 ASN n 
3 363 TYR n 
3 364 LEU n 
3 365 PHE n 
3 366 SER n 
3 367 ASP n 
3 368 LEU n 
3 369 ASP n 
3 370 PRO n 
3 371 ASP n 
3 372 THR n 
3 373 LYS n 
3 374 TYR n 
3 375 LYS n 
3 376 ALA n 
3 377 PHE n 
3 378 VAL n 
3 379 ARG n 
3 380 CYS n 
3 381 ALA n 
3 382 SER n 
3 383 ALA n 
3 384 ASN n 
3 385 HIS n 
3 386 PHE n 
3 387 TRP n 
3 388 LYS n 
3 389 TRP n 
3 390 SER n 
3 391 ASP n 
3 392 TRP n 
3 393 THR n 
3 394 GLN n 
3 395 LYS n 
3 396 GLU n 
3 397 PHE n 
3 398 SER n 
3 399 THR n 
3 400 PRO n 
3 401 GLU n 
3 402 THR n 
3 403 ALA n 
3 404 PRO n 
3 405 SER n 
3 406 GLN n 
3 407 ALA n 
3 408 LEU n 
3 409 ASP n 
3 410 VAL n 
3 411 TRP n 
3 412 ARG n 
3 413 GLN n 
3 414 VAL n 
3 415 TRP n 
3 416 SER n 
3 417 GLU n 
3 418 ASN n 
3 419 GLY n 
3 420 ARG n 
3 421 ARG n 
3 422 ILE n 
3 423 VAL n 
3 424 THR n 
3 425 LEU n 
3 426 PHE n 
3 427 TRP n 
3 428 LYS n 
3 429 PRO n 
3 430 LEU n 
3 431 LEU n 
3 432 LYS n 
3 433 SER n 
3 434 GLN n 
3 435 ALA n 
3 436 ASN n 
3 437 GLY n 
3 438 LYS n 
3 439 ILE n 
3 440 ILE n 
3 441 SER n 
3 442 TYR n 
3 443 ASN n 
3 444 ILE n 
3 445 VAL n 
3 446 VAL n 
3 447 GLU n 
3 448 ASN n 
3 449 GLU n 
3 450 ALA n 
3 451 LYS n 
3 452 PRO n 
3 453 THR n 
3 454 GLU n 
3 455 SER n 
3 456 GLU n 
3 457 HIS n 
3 458 TYR n 
3 459 CYS n 
3 460 VAL n 
3 461 TRP n 
3 462 ALA n 
3 463 PRO n 
3 464 ALA n 
3 465 LEU n 
3 466 SER n 
3 467 THR n 
3 468 ASN n 
3 469 LEU n 
3 470 SER n 
3 471 LEU n 
3 472 ASP n 
3 473 LEU n 
3 474 GLN n 
3 475 PRO n 
3 476 TYR n 
3 477 LYS n 
3 478 ILE n 
3 479 ARG n 
3 480 ILE n 
3 481 THR n 
3 482 THR n 
3 483 ASN n 
3 484 ASN n 
3 485 SER n 
3 486 MET n 
3 487 GLY n 
3 488 ALA n 
3 489 SER n 
3 490 PRO n 
3 491 GLU n 
3 492 SER n 
3 493 LEU n 
3 494 MET n 
3 495 VAL n 
3 496 LEU n 
3 497 SER n 
3 498 ASN n 
3 499 ASP n 
3 500 SER n 
3 501 GLY n 
3 502 HIS n 
3 503 GLU n 
3 504 GLU n 
3 505 VAL n 
3 506 LYS n 
3 507 GLU n 
3 508 LYS n 
3 509 THR n 
3 510 ILE n 
3 511 LYS n 
3 512 GLY n 
3 513 ILE n 
3 514 LYS n 
3 515 ASP n 
3 516 ALA n 
3 517 PHE n 
3 518 ASN n 
3 519 ILE n 
3 520 SER n 
3 521 TRP n 
3 522 GLU n 
3 523 PRO n 
3 524 VAL n 
3 525 SER n 
3 526 GLY n 
3 527 ASP n 
3 528 THR n 
3 529 MET n 
3 530 GLY n 
3 531 TYR n 
3 532 VAL n 
3 533 VAL n 
3 534 ASP n 
3 535 TRP n 
3 536 CYS n 
3 537 ALA n 
3 538 HIS n 
3 539 SER n 
3 540 GLN n 
3 541 ASP n 
3 542 GLN n 
3 543 ARG n 
3 544 CYS n 
3 545 ASP n 
3 546 LEU n 
3 547 GLN n 
3 548 TRP n 
3 549 LYS n 
3 550 ASN n 
3 551 LEU n 
3 552 GLY n 
3 553 PRO n 
3 554 ASN n 
3 555 THR n 
3 556 THR n 
3 557 SER n 
3 558 THR n 
3 559 THR n 
3 560 ILE n 
3 561 THR n 
3 562 SER n 
3 563 ASP n 
3 564 ASP n 
3 565 PHE n 
3 566 LYS n 
3 567 PRO n 
3 568 GLY n 
3 569 VAL n 
3 570 ARG n 
3 571 TYR n 
3 572 ASN n 
3 573 PHE n 
3 574 ARG n 
3 575 ILE n 
3 576 PHE n 
3 577 GLU n 
3 578 ARG n 
3 579 SER n 
3 580 VAL n 
3 581 GLU n 
3 582 HIS n 
3 583 LYS n 
3 584 ALA n 
3 585 ARG n 
3 586 LEU n 
3 587 VAL n 
3 588 GLU n 
3 589 LYS n 
3 590 GLN n 
3 591 ARG n 
3 592 GLY n 
3 593 TYR n 
3 594 THR n 
3 595 GLN n 
3 596 GLU n 
3 597 LEU n 
3 598 ALA n 
3 599 PRO n 
3 600 LEU n 
3 601 VAL n 
3 602 ASN n 
3 603 PRO n 
3 604 LYS n 
3 605 VAL n 
3 606 GLU n 
3 607 ILE n 
3 608 PRO n 
3 609 TYR n 
3 610 SER n 
3 611 THR n 
3 612 PRO n 
3 613 ASN n 
3 614 SER n 
3 615 PHE n 
3 616 VAL n 
3 617 LEU n 
3 618 ARG n 
3 619 TRP n 
3 620 PRO n 
3 621 ASP n 
3 622 TYR n 
3 623 ASP n 
3 624 SER n 
3 625 ASP n 
3 626 PHE n 
3 627 GLN n 
3 628 ALA n 
3 629 GLY n 
3 630 PHE n 
3 631 ILE n 
3 632 LYS n 
3 633 GLY n 
3 634 TYR n 
3 635 LEU n 
3 636 VAL n 
3 637 TYR n 
3 638 VAL n 
3 639 LYS n 
3 640 SER n 
3 641 LYS n 
3 642 GLU n 
3 643 MET n 
3 644 GLN n 
3 645 CYS n 
3 646 ASN n 
3 647 GLN n 
3 648 PRO n 
3 649 TRP n 
3 650 GLU n 
3 651 ARG n 
3 652 THR n 
3 653 LEU n 
3 654 LEU n 
3 655 PRO n 
3 656 ASP n 
3 657 ASN n 
3 658 SER n 
3 659 VAL n 
3 660 LEU n 
3 661 CYS n 
3 662 LYS n 
3 663 TYR n 
3 664 ASP n 
3 665 ILE n 
3 666 ASN n 
3 667 GLY n 
3 668 SER n 
3 669 GLU n 
3 670 THR n 
3 671 LYS n 
3 672 THR n 
3 673 LEU n 
3 674 THR n 
3 675 VAL n 
3 676 GLU n 
3 677 ASN n 
3 678 LEU n 
3 679 GLN n 
3 680 PRO n 
3 681 GLU n 
3 682 SER n 
3 683 LEU n 
3 684 TYR n 
3 685 GLU n 
3 686 PHE n 
3 687 PHE n 
3 688 VAL n 
3 689 THR n 
3 690 PRO n 
3 691 TYR n 
3 692 THR n 
3 693 SER n 
3 694 ALA n 
3 695 GLY n 
3 696 PRO n 
3 697 GLY n 
3 698 PRO n 
3 699 ASN n 
3 700 GLU n 
3 701 THR n 
3 702 PHE n 
3 703 THR n 
3 704 LYS n 
3 705 VAL n 
3 706 THR n 
3 707 THR n 
3 708 PRO n 
3 709 ASP n 
3 710 ALA n 
3 711 ARG n 
3 712 SER n 
3 713 HIS n 
3 714 MET n 
3 715 LEU n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 183 'house mouse' ? Osm   ? ? ? ? ? ? 'Mus musculus' 10090 ? ? ? ? ? ? ? ? 'Escherichia coli'   
562   ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 623 'house mouse' ? Il6st ? ? ? ? ? ? 'Mus musculus' 10090 ? ? ? ? ? ? ? ? 'Cricetulus griseus' 
10029 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
3 1 sample 'Biological sequence' 1 715 'house mouse' ? Osmr  ? ? ? ? ? ? 'Mus musculus' 10090 ? ? ? ? ? ? ? ? 'Homo sapiens'       
9606  ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
_pdbx_entity_branch.entity_id   4 
_pdbx_entity_branch.type        oligosaccharide 
# 
loop_
_pdbx_entity_branch_descriptor.ordinal 
_pdbx_entity_branch_descriptor.entity_id 
_pdbx_entity_branch_descriptor.descriptor 
_pdbx_entity_branch_descriptor.type 
_pdbx_entity_branch_descriptor.program 
_pdbx_entity_branch_descriptor.program_version 
1 4 DGlcpNAcb1-4DGlcpNAcb1-                               'Glycam Condensed Sequence' GMML       1.0   
2 4 'WURCS=2.0/1,2,1/[a2122h-1b_1-5_2*NCC/3=O]/1-1/a4-b1' WURCS                       PDB2Glycan 1.1.0 
3 4 '[]{[(4+1)][b-D-GlcpNAc]{[(4+1)][b-D-GlcpNAc]{}}}'    LINUCS                      PDB-CARE   ?     
# 
_pdbx_entity_branch_link.link_id                    1 
_pdbx_entity_branch_link.entity_id                  4 
_pdbx_entity_branch_link.entity_branch_list_num_1   2 
_pdbx_entity_branch_link.comp_id_1                  NAG 
_pdbx_entity_branch_link.atom_id_1                  C1 
_pdbx_entity_branch_link.leaving_atom_id_1          O1 
_pdbx_entity_branch_link.entity_branch_list_num_2   1 
_pdbx_entity_branch_link.comp_id_2                  NAG 
_pdbx_entity_branch_link.atom_id_2                  O4 
_pdbx_entity_branch_link.leaving_atom_id_2          HO4 
_pdbx_entity_branch_link.value_order                sing 
_pdbx_entity_branch_link.details                    ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking'          y ALANINE                                  ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking'          y ARGININE                                 ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking'          y ASPARAGINE                               ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking'          y 'ASPARTIC ACID'                          ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking'          y CYSTEINE                                 ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking'          y GLUTAMINE                                ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking'          y 'GLUTAMIC ACID'                          ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'            y GLYCINE                                  ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking'          y HISTIDINE                                ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking'          y ISOLEUCINE                               ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking'          y LEUCINE                                  ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking'          y LYSINE                                   ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking'          y METHIONINE                               ? 'C5 H11 N O2 S'  149.211 
NAG 'D-saccharide, beta linking' . 2-acetamido-2-deoxy-beta-D-glucopyranose 
;N-acetyl-beta-D-glucosamine; 2-acetamido-2-deoxy-beta-D-glucose; 2-acetamido-2-deoxy-D-glucose; 2-acetamido-2-deoxy-glucose; N-ACETYL-D-GLUCOSAMINE
;
'C8 H15 N O6'    221.208 
PHE 'L-peptide linking'          y PHENYLALANINE                            ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking'          y PROLINE                                  ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking'          y SERINE                                   ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking'          y THREONINE                                ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking'          y TRYPTOPHAN                               ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking'          y TYROSINE                                 ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking'          y VALINE                                   ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_chem_comp_identifier.comp_id 
_pdbx_chem_comp_identifier.type 
_pdbx_chem_comp_identifier.program 
_pdbx_chem_comp_identifier.program_version 
_pdbx_chem_comp_identifier.identifier 
NAG 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DGlcpNAcb                      
NAG 'COMMON NAME'                         GMML     1.0 N-acetyl-b-D-glucopyranosamine 
NAG 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 b-D-GlcpNAc                    
NAG 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 GlcNAc                         
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   ALA 1   24  24  ALA ALA A . n 
A 1 2   ASN 2   25  25  ASN ASN A . n 
A 1 3   ARG 3   26  26  ARG ARG A . n 
A 1 4   GLY 4   27  27  GLY GLY A . n 
A 1 5   CYS 5   28  28  CYS CYS A . n 
A 1 6   SER 6   29  29  SER SER A . n 
A 1 7   ASN 7   30  30  ASN ASN A . n 
A 1 8   SER 8   31  31  SER SER A . n 
A 1 9   SER 9   32  32  SER SER A . n 
A 1 10  SER 10  33  33  SER SER A . n 
A 1 11  GLN 11  34  34  GLN GLN A . n 
A 1 12  LEU 12  35  35  LEU LEU A . n 
A 1 13  LEU 13  36  36  LEU LEU A . n 
A 1 14  SER 14  37  37  SER SER A . n 
A 1 15  GLN 15  38  38  GLN GLN A . n 
A 1 16  LEU 16  39  39  LEU LEU A . n 
A 1 17  GLN 17  40  40  GLN GLN A . n 
A 1 18  ASN 18  41  41  ASN ASN A . n 
A 1 19  GLN 19  42  42  GLN GLN A . n 
A 1 20  ALA 20  43  43  ALA ALA A . n 
A 1 21  ASN 21  44  44  ASN ASN A . n 
A 1 22  LEU 22  45  45  LEU LEU A . n 
A 1 23  THR 23  46  46  THR THR A . n 
A 1 24  GLY 24  47  47  GLY GLY A . n 
A 1 25  ASN 25  48  48  ASN ASN A . n 
A 1 26  THR 26  49  49  THR THR A . n 
A 1 27  GLU 27  50  50  GLU GLU A . n 
A 1 28  SER 28  51  51  SER SER A . n 
A 1 29  LEU 29  52  52  LEU LEU A . n 
A 1 30  LEU 30  53  53  LEU LEU A . n 
A 1 31  GLU 31  54  54  GLU GLU A . n 
A 1 32  PRO 32  55  55  PRO PRO A . n 
A 1 33  TYR 33  56  56  TYR TYR A . n 
A 1 34  ILE 34  57  57  ILE ILE A . n 
A 1 35  ARG 35  58  58  ARG ARG A . n 
A 1 36  LEU 36  59  59  LEU LEU A . n 
A 1 37  GLN 37  60  60  GLN GLN A . n 
A 1 38  ASN 38  61  61  ASN ASN A . n 
A 1 39  LEU 39  62  62  LEU LEU A . n 
A 1 40  ASN 40  63  63  ASN ASN A . n 
A 1 41  THR 41  64  64  THR THR A . n 
A 1 42  PRO 42  65  65  PRO PRO A . n 
A 1 43  ASP 43  66  66  ASP ASP A . n 
A 1 44  LEU 44  67  67  LEU LEU A . n 
A 1 45  ARG 45  68  68  ARG ARG A . n 
A 1 46  ALA 46  69  69  ALA ALA A . n 
A 1 47  ALA 47  70  70  ALA ALA A . n 
A 1 48  CYS 48  71  71  CYS CYS A . n 
A 1 49  THR 49  72  72  THR THR A . n 
A 1 50  GLN 50  73  73  GLN GLN A . n 
A 1 51  HIS 51  74  74  HIS HIS A . n 
A 1 52  SER 52  75  75  SER SER A . n 
A 1 53  VAL 53  76  76  VAL VAL A . n 
A 1 54  ALA 54  77  77  ALA ALA A . n 
A 1 55  PHE 55  78  78  PHE PHE A . n 
A 1 56  PRO 56  79  79  PRO PRO A . n 
A 1 57  SER 57  80  80  SER SER A . n 
A 1 58  GLU 58  81  81  GLU GLU A . n 
A 1 59  ASP 59  82  82  ASP ASP A . n 
A 1 60  THR 60  83  83  THR THR A . n 
A 1 61  LEU 61  84  84  LEU LEU A . n 
A 1 62  ARG 62  85  85  ARG ARG A . n 
A 1 63  GLN 63  86  86  GLN GLN A . n 
A 1 64  LEU 64  87  87  LEU LEU A . n 
A 1 65  SER 65  88  88  SER SER A . n 
A 1 66  LYS 66  89  89  LYS LYS A . n 
A 1 67  PRO 67  90  90  PRO PRO A . n 
A 1 68  HIS 68  91  91  HIS HIS A . n 
A 1 69  PHE 69  92  92  PHE PHE A . n 
A 1 70  LEU 70  93  93  LEU LEU A . n 
A 1 71  SER 71  94  94  SER SER A . n 
A 1 72  THR 72  95  95  THR THR A . n 
A 1 73  VAL 73  96  96  VAL VAL A . n 
A 1 74  TYR 74  97  97  TYR TYR A . n 
A 1 75  THR 75  98  98  THR THR A . n 
A 1 76  THR 76  99  99  THR THR A . n 
A 1 77  LEU 77  100 100 LEU LEU A . n 
A 1 78  ASP 78  101 101 ASP ASP A . n 
A 1 79  ARG 79  102 102 ARG ARG A . n 
A 1 80  VAL 80  103 103 VAL VAL A . n 
A 1 81  LEU 81  104 104 LEU LEU A . n 
A 1 82  TYR 82  105 105 TYR TYR A . n 
A 1 83  GLN 83  106 106 GLN GLN A . n 
A 1 84  LEU 84  107 107 LEU LEU A . n 
A 1 85  ASP 85  108 108 ASP ASP A . n 
A 1 86  ALA 86  109 109 ALA ALA A . n 
A 1 87  LEU 87  110 110 LEU LEU A . n 
A 1 88  ARG 88  111 111 ARG ARG A . n 
A 1 89  GLN 89  112 112 GLN GLN A . n 
A 1 90  LYS 90  113 113 LYS LYS A . n 
A 1 91  PHE 91  114 114 PHE PHE A . n 
A 1 92  LEU 92  115 115 LEU LEU A . n 
A 1 93  LYS 93  116 116 LYS LYS A . n 
A 1 94  THR 94  117 117 THR THR A . n 
A 1 95  PRO 95  118 118 PRO PRO A . n 
A 1 96  ALA 96  119 119 ALA ALA A . n 
A 1 97  PHE 97  120 120 PHE PHE A . n 
A 1 98  PRO 98  121 121 PRO PRO A . n 
A 1 99  LYS 99  122 122 LYS LYS A . n 
A 1 100 LEU 100 123 123 LEU LEU A . n 
A 1 101 ASP 101 124 124 ASP ASP A . n 
A 1 102 SER 102 125 125 SER SER A . n 
A 1 103 ALA 103 126 126 ALA ALA A . n 
A 1 104 ARG 104 127 127 ARG ARG A . n 
A 1 105 HIS 105 128 128 HIS HIS A . n 
A 1 106 ASN 106 129 129 ASN ASN A . n 
A 1 107 ILE 107 130 130 ILE ILE A . n 
A 1 108 LEU 108 131 131 LEU LEU A . n 
A 1 109 GLY 109 132 132 GLY GLY A . n 
A 1 110 ILE 110 133 133 ILE ILE A . n 
A 1 111 ARG 111 134 134 ARG ARG A . n 
A 1 112 ASN 112 135 135 ASN ASN A . n 
A 1 113 ASN 113 136 136 ASN ASN A . n 
A 1 114 VAL 114 137 137 VAL VAL A . n 
A 1 115 PHE 115 138 138 PHE PHE A . n 
A 1 116 CYS 116 139 139 CYS CYS A . n 
A 1 117 MET 117 140 140 MET MET A . n 
A 1 118 ALA 118 141 141 ALA ALA A . n 
A 1 119 ARG 119 142 142 ARG ARG A . n 
A 1 120 LEU 120 143 143 LEU LEU A . n 
A 1 121 LEU 121 144 144 LEU LEU A . n 
A 1 122 ASN 122 145 145 ASN ASN A . n 
A 1 123 HIS 123 146 146 HIS HIS A . n 
A 1 124 SER 124 147 147 SER SER A . n 
A 1 125 LEU 125 148 148 LEU LEU A . n 
A 1 126 GLU 126 149 149 GLU GLU A . n 
A 1 127 ILE 127 150 150 ILE ILE A . n 
A 1 128 PRO 128 151 151 PRO PRO A . n 
A 1 129 GLU 129 152 ?   ?   ?   A . n 
A 1 130 PRO 130 153 ?   ?   ?   A . n 
A 1 131 THR 131 154 ?   ?   ?   A . n 
A 1 132 GLN 132 155 ?   ?   ?   A . n 
A 1 133 THR 133 156 ?   ?   ?   A . n 
A 1 134 ASP 134 157 ?   ?   ?   A . n 
A 1 135 SER 135 158 ?   ?   ?   A . n 
A 1 136 GLY 136 159 ?   ?   ?   A . n 
A 1 137 ALA 137 160 ?   ?   ?   A . n 
A 1 138 SER 138 161 ?   ?   ?   A . n 
A 1 139 ARG 139 162 162 ARG ARG A . n 
A 1 140 SER 140 163 163 SER SER A . n 
A 1 141 THR 141 164 164 THR THR A . n 
A 1 142 THR 142 165 165 THR THR A . n 
A 1 143 THR 143 166 166 THR THR A . n 
A 1 144 PRO 144 167 167 PRO PRO A . n 
A 1 145 ASP 145 168 168 ASP ASP A . n 
A 1 146 VAL 146 169 169 VAL VAL A . n 
A 1 147 PHE 147 170 170 PHE PHE A . n 
A 1 148 ASN 148 171 171 ASN ASN A . n 
A 1 149 THR 149 172 172 THR THR A . n 
A 1 150 LYS 150 173 173 LYS LYS A . n 
A 1 151 ILE 151 174 174 ILE ILE A . n 
A 1 152 GLY 152 175 175 GLY GLY A . n 
A 1 153 SER 153 176 176 SER SER A . n 
A 1 154 CYS 154 177 177 CYS CYS A . n 
A 1 155 GLY 155 178 178 GLY GLY A . n 
A 1 156 PHE 156 179 179 PHE PHE A . n 
A 1 157 LEU 157 180 180 LEU LEU A . n 
A 1 158 TRP 158 181 181 TRP TRP A . n 
A 1 159 GLY 159 182 182 GLY GLY A . n 
A 1 160 TYR 160 183 183 TYR TYR A . n 
A 1 161 HIS 161 184 184 HIS HIS A . n 
A 1 162 ARG 162 185 185 ARG ARG A . n 
A 1 163 PHE 163 186 186 PHE PHE A . n 
A 1 164 MET 164 187 187 MET MET A . n 
A 1 165 GLY 165 188 188 GLY GLY A . n 
A 1 166 SER 166 189 189 SER SER A . n 
A 1 167 VAL 167 190 190 VAL VAL A . n 
A 1 168 GLY 168 191 191 GLY GLY A . n 
A 1 169 ARG 169 192 192 ARG ARG A . n 
A 1 170 VAL 170 193 193 VAL VAL A . n 
A 1 171 PHE 171 194 194 PHE PHE A . n 
A 1 172 ARG 172 195 195 ARG ARG A . n 
A 1 173 GLU 173 196 196 GLU GLU A . n 
A 1 174 TRP 174 197 197 TRP TRP A . n 
A 1 175 ASP 175 198 198 ASP ASP A . n 
A 1 176 ASP 176 199 199 ASP ASP A . n 
A 1 177 GLY 177 200 200 GLY GLY A . n 
A 1 178 SER 178 201 201 SER SER A . n 
A 1 179 THR 179 202 202 THR THR A . n 
A 1 180 ARG 180 203 ?   ?   ?   A . n 
A 1 181 SER 181 204 ?   ?   ?   A . n 
A 1 182 ARG 182 205 ?   ?   ?   A . n 
A 1 183 ARG 183 206 ?   ?   ?   A . n 
B 2 1   GLN 1   23  ?   ?   ?   B . n 
B 2 2   LEU 2   24  ?   ?   ?   B . n 
B 2 3   LEU 3   25  ?   ?   ?   B . n 
B 2 4   GLU 4   26  ?   ?   ?   B . n 
B 2 5   PRO 5   27  27  PRO PRO B . n 
B 2 6   CYS 6   28  28  CYS CYS B . n 
B 2 7   GLY 7   29  29  GLY GLY B . n 
B 2 8   TYR 8   30  30  TYR TYR B . n 
B 2 9   ILE 9   31  31  ILE ILE B . n 
B 2 10  TYR 10  32  32  TYR TYR B . n 
B 2 11  PRO 11  33  33  PRO PRO B . n 
B 2 12  GLU 12  34  34  GLU GLU B . n 
B 2 13  PHE 13  35  35  PHE PHE B . n 
B 2 14  PRO 14  36  36  PRO PRO B . n 
B 2 15  VAL 15  37  37  VAL VAL B . n 
B 2 16  VAL 16  38  38  VAL VAL B . n 
B 2 17  GLN 17  39  39  GLN GLN B . n 
B 2 18  ARG 18  40  40  ARG ARG B . n 
B 2 19  GLY 19  41  41  GLY GLY B . n 
B 2 20  SER 20  42  42  SER SER B . n 
B 2 21  ASN 21  43  43  ASN ASN B . n 
B 2 22  PHE 22  44  44  PHE PHE B . n 
B 2 23  THR 23  45  45  THR THR B . n 
B 2 24  ALA 24  46  46  ALA ALA B . n 
B 2 25  ILE 25  47  47  ILE ILE B . n 
B 2 26  CYS 26  48  48  CYS CYS B . n 
B 2 27  VAL 27  49  49  VAL VAL B . n 
B 2 28  LEU 28  50  50  LEU LEU B . n 
B 2 29  LYS 29  51  51  LYS LYS B . n 
B 2 30  GLU 30  52  52  GLU GLU B . n 
B 2 31  ALA 31  53  53  ALA ALA B . n 
B 2 32  CYS 32  54  54  CYS CYS B . n 
B 2 33  LEU 33  55  55  LEU LEU B . n 
B 2 34  GLN 34  56  56  GLN GLN B . n 
B 2 35  HIS 35  57  57  HIS HIS B . n 
B 2 36  TYR 36  58  58  TYR TYR B . n 
B 2 37  TYR 37  59  59  TYR TYR B . n 
B 2 38  VAL 38  60  60  VAL VAL B . n 
B 2 39  ASN 39  61  61  ASN ASN B . n 
B 2 40  ALA 40  62  62  ALA ALA B . n 
B 2 41  SER 41  63  63  SER SER B . n 
B 2 42  TYR 42  64  64  TYR TYR B . n 
B 2 43  ILE 43  65  65  ILE ILE B . n 
B 2 44  VAL 44  66  66  VAL VAL B . n 
B 2 45  TRP 45  67  67  TRP TRP B . n 
B 2 46  LYS 46  68  68  LYS LYS B . n 
B 2 47  THR 47  69  69  THR THR B . n 
B 2 48  ASN 48  70  70  ASN ASN B . n 
B 2 49  HIS 49  71  71  HIS HIS B . n 
B 2 50  ALA 50  72  72  ALA ALA B . n 
B 2 51  ALA 51  73  73  ALA ALA B . n 
B 2 52  VAL 52  74  74  VAL VAL B . n 
B 2 53  PRO 53  75  75  PRO PRO B . n 
B 2 54  ARG 54  76  76  ARG ARG B . n 
B 2 55  GLU 55  77  77  GLU GLU B . n 
B 2 56  GLN 56  78  78  GLN GLN B . n 
B 2 57  VAL 57  79  79  VAL VAL B . n 
B 2 58  THR 58  80  80  THR THR B . n 
B 2 59  VAL 59  81  81  VAL VAL B . n 
B 2 60  ILE 60  82  82  ILE ILE B . n 
B 2 61  ASN 61  83  83  ASN ASN B . n 
B 2 62  ARG 62  84  84  ARG ARG B . n 
B 2 63  THR 63  85  85  THR THR B . n 
B 2 64  THR 64  86  86  THR THR B . n 
B 2 65  SER 65  87  87  SER SER B . n 
B 2 66  SER 66  88  88  SER SER B . n 
B 2 67  VAL 67  89  89  VAL VAL B . n 
B 2 68  THR 68  90  90  THR THR B . n 
B 2 69  PHE 69  91  91  PHE PHE B . n 
B 2 70  THR 70  92  92  THR THR B . n 
B 2 71  ASP 71  93  93  ASP ASP B . n 
B 2 72  VAL 72  94  94  VAL VAL B . n 
B 2 73  VAL 73  95  95  VAL VAL B . n 
B 2 74  LEU 74  96  96  LEU LEU B . n 
B 2 75  PRO 75  97  97  PRO PRO B . n 
B 2 76  SER 76  98  98  SER SER B . n 
B 2 77  VAL 77  99  99  VAL VAL B . n 
B 2 78  GLN 78  100 100 GLN GLN B . n 
B 2 79  LEU 79  101 101 LEU LEU B . n 
B 2 80  THR 80  102 102 THR THR B . n 
B 2 81  CYS 81  103 103 CYS CYS B . n 
B 2 82  ASN 82  104 104 ASN ASN B . n 
B 2 83  ILE 83  105 105 ILE ILE B . n 
B 2 84  LEU 84  106 106 LEU LEU B . n 
B 2 85  SER 85  107 107 SER SER B . n 
B 2 86  PHE 86  108 108 PHE PHE B . n 
B 2 87  GLY 87  109 109 GLY GLY B . n 
B 2 88  GLN 88  110 110 GLN GLN B . n 
B 2 89  ILE 89  111 111 ILE ILE B . n 
B 2 90  GLU 90  112 112 GLU GLU B . n 
B 2 91  GLN 91  113 113 GLN GLN B . n 
B 2 92  ASN 92  114 114 ASN ASN B . n 
B 2 93  VAL 93  115 115 VAL VAL B . n 
B 2 94  TYR 94  116 116 TYR TYR B . n 
B 2 95  GLY 95  117 117 GLY GLY B . n 
B 2 96  VAL 96  118 118 VAL VAL B . n 
B 2 97  THR 97  119 119 THR THR B . n 
B 2 98  MET 98  120 120 MET MET B . n 
B 2 99  LEU 99  121 121 LEU LEU B . n 
B 2 100 SER 100 122 122 SER SER B . n 
B 2 101 GLY 101 123 123 GLY GLY B . n 
B 2 102 PHE 102 124 124 PHE PHE B . n 
B 2 103 PRO 103 125 125 PRO PRO B . n 
B 2 104 PRO 104 126 126 PRO PRO B . n 
B 2 105 ASP 105 127 127 ASP ASP B . n 
B 2 106 LYS 106 128 128 LYS LYS B . n 
B 2 107 PRO 107 129 129 PRO PRO B . n 
B 2 108 THR 108 130 130 THR THR B . n 
B 2 109 ASN 109 131 131 ASN ASN B . n 
B 2 110 LEU 110 132 132 LEU LEU B . n 
B 2 111 THR 111 133 133 THR THR B . n 
B 2 112 CYS 112 134 134 CYS CYS B . n 
B 2 113 ILE 113 135 135 ILE ILE B . n 
B 2 114 VAL 114 136 136 VAL VAL B . n 
B 2 115 ASN 115 137 137 ASN ASN B . n 
B 2 116 GLU 116 138 138 GLU GLU B . n 
B 2 117 GLY 117 139 139 GLY GLY B . n 
B 2 118 LYS 118 140 140 LYS LYS B . n 
B 2 119 ASN 119 141 141 ASN ASN B . n 
B 2 120 MET 120 142 142 MET MET B . n 
B 2 121 LEU 121 143 143 LEU LEU B . n 
B 2 122 CYS 122 144 144 CYS CYS B . n 
B 2 123 GLN 123 145 145 GLN GLN B . n 
B 2 124 TRP 124 146 146 TRP TRP B . n 
B 2 125 ASP 125 147 147 ASP ASP B . n 
B 2 126 PRO 126 148 148 PRO PRO B . n 
B 2 127 GLY 127 149 149 GLY GLY B . n 
B 2 128 ARG 128 150 150 ARG ARG B . n 
B 2 129 GLU 129 151 151 GLU GLU B . n 
B 2 130 THR 130 152 152 THR THR B . n 
B 2 131 TYR 131 153 153 TYR TYR B . n 
B 2 132 LEU 132 154 154 LEU LEU B . n 
B 2 133 GLU 133 155 155 GLU GLU B . n 
B 2 134 THR 134 156 156 THR THR B . n 
B 2 135 ASN 135 157 157 ASN ASN B . n 
B 2 136 TYR 136 158 158 TYR TYR B . n 
B 2 137 THR 137 159 159 THR THR B . n 
B 2 138 LEU 138 160 160 LEU LEU B . n 
B 2 139 LYS 139 161 161 LYS LYS B . n 
B 2 140 SER 140 162 162 SER SER B . n 
B 2 141 GLU 141 163 163 GLU GLU B . n 
B 2 142 TRP 142 164 164 TRP TRP B . n 
B 2 143 ALA 143 165 165 ALA ALA B . n 
B 2 144 THR 144 166 166 THR THR B . n 
B 2 145 GLU 145 167 167 GLU GLU B . n 
B 2 146 LYS 146 168 168 LYS LYS B . n 
B 2 147 PHE 147 169 169 PHE PHE B . n 
B 2 148 PRO 148 170 170 PRO PRO B . n 
B 2 149 ASP 149 171 171 ASP ASP B . n 
B 2 150 CYS 150 172 172 CYS CYS B . n 
B 2 151 GLN 151 173 173 GLN GLN B . n 
B 2 152 SER 152 174 174 SER SER B . n 
B 2 153 LYS 153 175 175 LYS LYS B . n 
B 2 154 HIS 154 176 176 HIS HIS B . n 
B 2 155 GLY 155 177 177 GLY GLY B . n 
B 2 156 THR 156 178 178 THR THR B . n 
B 2 157 SER 157 179 179 SER SER B . n 
B 2 158 CYS 158 180 180 CYS CYS B . n 
B 2 159 MET 159 181 181 MET MET B . n 
B 2 160 VAL 160 182 182 VAL VAL B . n 
B 2 161 SER 161 183 183 SER SER B . n 
B 2 162 TYR 162 184 184 TYR TYR B . n 
B 2 163 MET 163 185 185 MET MET B . n 
B 2 164 PRO 164 186 186 PRO PRO B . n 
B 2 165 THR 165 187 187 THR THR B . n 
B 2 166 TYR 166 188 188 TYR TYR B . n 
B 2 167 TYR 167 189 189 TYR TYR B . n 
B 2 168 VAL 168 190 190 VAL VAL B . n 
B 2 169 ASN 169 191 191 ASN ASN B . n 
B 2 170 ILE 170 192 192 ILE ILE B . n 
B 2 171 GLU 171 193 193 GLU GLU B . n 
B 2 172 VAL 172 194 194 VAL VAL B . n 
B 2 173 TRP 173 195 195 TRP TRP B . n 
B 2 174 VAL 174 196 196 VAL VAL B . n 
B 2 175 GLU 175 197 197 GLU GLU B . n 
B 2 176 ALA 176 198 198 ALA ALA B . n 
B 2 177 GLU 177 199 199 GLU GLU B . n 
B 2 178 ASN 178 200 200 ASN ASN B . n 
B 2 179 ALA 179 201 201 ALA ALA B . n 
B 2 180 LEU 180 202 202 LEU LEU B . n 
B 2 181 GLY 181 203 203 GLY GLY B . n 
B 2 182 LYS 182 204 204 LYS LYS B . n 
B 2 183 VAL 183 205 205 VAL VAL B . n 
B 2 184 SER 184 206 206 SER SER B . n 
B 2 185 SER 185 207 207 SER SER B . n 
B 2 186 GLU 186 208 208 GLU GLU B . n 
B 2 187 SER 187 209 209 SER SER B . n 
B 2 188 ILE 188 210 210 ILE ILE B . n 
B 2 189 ASN 189 211 211 ASN ASN B . n 
B 2 190 PHE 190 212 212 PHE PHE B . n 
B 2 191 ASP 191 213 213 ASP ASP B . n 
B 2 192 PRO 192 214 214 PRO PRO B . n 
B 2 193 VAL 193 215 215 VAL VAL B . n 
B 2 194 ASP 194 216 216 ASP ASP B . n 
B 2 195 LYS 195 217 217 LYS LYS B . n 
B 2 196 VAL 196 218 218 VAL VAL B . n 
B 2 197 LYS 197 219 219 LYS LYS B . n 
B 2 198 PRO 198 220 220 PRO PRO B . n 
B 2 199 THR 199 221 221 THR THR B . n 
B 2 200 PRO 200 222 222 PRO PRO B . n 
B 2 201 PRO 201 223 223 PRO PRO B . n 
B 2 202 TYR 202 224 224 TYR TYR B . n 
B 2 203 ASN 203 225 225 ASN ASN B . n 
B 2 204 LEU 204 226 226 LEU LEU B . n 
B 2 205 SER 205 227 227 SER SER B . n 
B 2 206 VAL 206 228 228 VAL VAL B . n 
B 2 207 THR 207 229 229 THR THR B . n 
B 2 208 ASN 208 230 230 ASN ASN B . n 
B 2 209 SER 209 231 231 SER SER B . n 
B 2 210 GLU 210 232 232 GLU GLU B . n 
B 2 211 GLU 211 233 233 GLU GLU B . n 
B 2 212 LEU 212 234 234 LEU LEU B . n 
B 2 213 SER 213 235 235 SER SER B . n 
B 2 214 SER 214 236 236 SER SER B . n 
B 2 215 ILE 215 237 237 ILE ILE B . n 
B 2 216 LEU 216 238 238 LEU LEU B . n 
B 2 217 LYS 217 239 239 LYS LYS B . n 
B 2 218 LEU 218 240 240 LEU LEU B . n 
B 2 219 SER 219 241 241 SER SER B . n 
B 2 220 TRP 220 242 242 TRP TRP B . n 
B 2 221 VAL 221 243 243 VAL VAL B . n 
B 2 222 SER 222 244 244 SER SER B . n 
B 2 223 SER 223 245 245 SER SER B . n 
B 2 224 GLY 224 246 246 GLY GLY B . n 
B 2 225 LEU 225 247 247 LEU LEU B . n 
B 2 226 GLY 226 248 248 GLY GLY B . n 
B 2 227 GLY 227 249 249 GLY GLY B . n 
B 2 228 LEU 228 250 250 LEU LEU B . n 
B 2 229 LEU 229 251 251 LEU LEU B . n 
B 2 230 ASP 230 252 252 ASP ASP B . n 
B 2 231 LEU 231 253 253 LEU LEU B . n 
B 2 232 LYS 232 254 254 LYS LYS B . n 
B 2 233 SER 233 255 255 SER SER B . n 
B 2 234 ASP 234 256 256 ASP ASP B . n 
B 2 235 ILE 235 257 257 ILE ILE B . n 
B 2 236 GLN 236 258 258 GLN GLN B . n 
B 2 237 TYR 237 259 259 TYR TYR B . n 
B 2 238 ARG 238 260 260 ARG ARG B . n 
B 2 239 THR 239 261 261 THR THR B . n 
B 2 240 LYS 240 262 262 LYS LYS B . n 
B 2 241 ASP 241 263 263 ASP ASP B . n 
B 2 242 ALA 242 264 264 ALA ALA B . n 
B 2 243 SER 243 265 265 SER SER B . n 
B 2 244 THR 244 266 266 THR THR B . n 
B 2 245 TRP 245 267 267 TRP TRP B . n 
B 2 246 ILE 246 268 268 ILE ILE B . n 
B 2 247 GLN 247 269 269 GLN GLN B . n 
B 2 248 VAL 248 270 270 VAL VAL B . n 
B 2 249 PRO 249 271 271 PRO PRO B . n 
B 2 250 LEU 250 272 272 LEU LEU B . n 
B 2 251 GLU 251 273 273 GLU GLU B . n 
B 2 252 ASP 252 274 274 ASP ASP B . n 
B 2 253 THR 253 275 275 THR THR B . n 
B 2 254 MET 254 276 276 MET MET B . n 
B 2 255 SER 255 277 277 SER SER B . n 
B 2 256 PRO 256 278 278 PRO PRO B . n 
B 2 257 ARG 257 279 279 ARG ARG B . n 
B 2 258 THR 258 280 280 THR THR B . n 
B 2 259 SER 259 281 281 SER SER B . n 
B 2 260 PHE 260 282 282 PHE PHE B . n 
B 2 261 THR 261 283 283 THR THR B . n 
B 2 262 VAL 262 284 284 VAL VAL B . n 
B 2 263 GLN 263 285 285 GLN GLN B . n 
B 2 264 ASP 264 286 286 ASP ASP B . n 
B 2 265 LEU 265 287 287 LEU LEU B . n 
B 2 266 LYS 266 288 288 LYS LYS B . n 
B 2 267 PRO 267 289 289 PRO PRO B . n 
B 2 268 PHE 268 290 290 PHE PHE B . n 
B 2 269 THR 269 291 291 THR THR B . n 
B 2 270 GLU 270 292 292 GLU GLU B . n 
B 2 271 TYR 271 293 293 TYR TYR B . n 
B 2 272 VAL 272 294 294 VAL VAL B . n 
B 2 273 PHE 273 295 295 PHE PHE B . n 
B 2 274 ARG 274 296 296 ARG ARG B . n 
B 2 275 ILE 275 297 297 ILE ILE B . n 
B 2 276 ARG 276 298 298 ARG ARG B . n 
B 2 277 SER 277 299 299 SER SER B . n 
B 2 278 ILE 278 300 300 ILE ILE B . n 
B 2 279 LYS 279 301 301 LYS LYS B . n 
B 2 280 ASP 280 302 302 ASP ASP B . n 
B 2 281 SER 281 303 303 SER SER B . n 
B 2 282 GLY 282 304 304 GLY GLY B . n 
B 2 283 LYS 283 305 305 LYS LYS B . n 
B 2 284 GLY 284 306 306 GLY GLY B . n 
B 2 285 TYR 285 307 307 TYR TYR B . n 
B 2 286 TRP 286 308 308 TRP TRP B . n 
B 2 287 SER 287 309 309 SER SER B . n 
B 2 288 ASP 288 310 310 ASP ASP B . n 
B 2 289 TRP 289 311 311 TRP TRP B . n 
B 2 290 SER 290 312 312 SER SER B . n 
B 2 291 GLU 291 313 313 GLU GLU B . n 
B 2 292 GLU 292 314 314 GLU GLU B . n 
B 2 293 ALA 293 315 315 ALA ALA B . n 
B 2 294 SER 294 316 316 SER SER B . n 
B 2 295 GLY 295 317 317 GLY GLY B . n 
B 2 296 THR 296 318 318 THR THR B . n 
B 2 297 THR 297 319 319 THR THR B . n 
B 2 298 TYR 298 320 320 TYR TYR B . n 
B 2 299 GLU 299 321 321 GLU GLU B . n 
B 2 300 ASP 300 322 322 ASP ASP B . n 
B 2 301 ARG 301 323 323 ARG ARG B . n 
B 2 302 PRO 302 324 324 PRO PRO B . n 
B 2 303 SER 303 325 325 SER SER B . n 
B 2 304 ARG 304 326 326 ARG ARG B . n 
B 2 305 PRO 305 327 327 PRO PRO B . n 
B 2 306 PRO 306 328 328 PRO PRO B . n 
B 2 307 SER 307 329 329 SER SER B . n 
B 2 308 PHE 308 330 330 PHE PHE B . n 
B 2 309 TRP 309 331 331 TRP TRP B . n 
B 2 310 TYR 310 332 332 TYR TYR B . n 
B 2 311 LYS 311 333 333 LYS LYS B . n 
B 2 312 THR 312 334 334 THR THR B . n 
B 2 313 ASN 313 335 335 ASN ASN B . n 
B 2 314 PRO 314 336 336 PRO PRO B . n 
B 2 315 SER 315 337 337 SER SER B . n 
B 2 316 HIS 316 338 338 HIS HIS B . n 
B 2 317 GLY 317 339 339 GLY GLY B . n 
B 2 318 GLN 318 340 340 GLN GLN B . n 
B 2 319 GLU 319 341 341 GLU GLU B . n 
B 2 320 TYR 320 342 342 TYR TYR B . n 
B 2 321 ARG 321 343 343 ARG ARG B . n 
B 2 322 SER 322 344 344 SER SER B . n 
B 2 323 VAL 323 345 345 VAL VAL B . n 
B 2 324 ARG 324 346 346 ARG ARG B . n 
B 2 325 LEU 325 347 347 LEU LEU B . n 
B 2 326 ILE 326 348 348 ILE ILE B . n 
B 2 327 TRP 327 349 349 TRP TRP B . n 
B 2 328 LYS 328 350 350 LYS LYS B . n 
B 2 329 ALA 329 351 351 ALA ALA B . n 
B 2 330 LEU 330 352 352 LEU LEU B . n 
B 2 331 PRO 331 353 353 PRO PRO B . n 
B 2 332 LEU 332 354 354 LEU LEU B . n 
B 2 333 SER 333 355 355 SER SER B . n 
B 2 334 GLU 334 356 356 GLU GLU B . n 
B 2 335 ALA 335 357 357 ALA ALA B . n 
B 2 336 ASN 336 358 358 ASN ASN B . n 
B 2 337 GLY 337 359 359 GLY GLY B . n 
B 2 338 LYS 338 360 360 LYS LYS B . n 
B 2 339 ILE 339 361 361 ILE ILE B . n 
B 2 340 LEU 340 362 362 LEU LEU B . n 
B 2 341 ASP 341 363 363 ASP ASP B . n 
B 2 342 TYR 342 364 364 TYR TYR B . n 
B 2 343 GLU 343 365 365 GLU GLU B . n 
B 2 344 VAL 344 366 366 VAL VAL B . n 
B 2 345 ILE 345 367 367 ILE ILE B . n 
B 2 346 LEU 346 368 368 LEU LEU B . n 
B 2 347 THR 347 369 369 THR THR B . n 
B 2 348 GLN 348 370 370 GLN GLN B . n 
B 2 349 SER 349 371 371 SER SER B . n 
B 2 350 LYS 350 372 372 LYS LYS B . n 
B 2 351 SER 351 373 373 SER SER B . n 
B 2 352 VAL 352 374 374 VAL VAL B . n 
B 2 353 SER 353 375 375 SER SER B . n 
B 2 354 GLN 354 376 376 GLN GLN B . n 
B 2 355 THR 355 377 377 THR THR B . n 
B 2 356 TYR 356 378 378 TYR TYR B . n 
B 2 357 THR 357 379 379 THR THR B . n 
B 2 358 VAL 358 380 380 VAL VAL B . n 
B 2 359 THR 359 381 381 THR THR B . n 
B 2 360 GLY 360 382 382 GLY GLY B . n 
B 2 361 THR 361 383 383 THR THR B . n 
B 2 362 GLU 362 384 384 GLU GLU B . n 
B 2 363 LEU 363 385 385 LEU LEU B . n 
B 2 364 THR 364 386 386 THR THR B . n 
B 2 365 VAL 365 387 387 VAL VAL B . n 
B 2 366 ASN 366 388 388 ASN ASN B . n 
B 2 367 LEU 367 389 389 LEU LEU B . n 
B 2 368 THR 368 390 390 THR THR B . n 
B 2 369 ASN 369 391 391 ASN ASN B . n 
B 2 370 ASP 370 392 392 ASP ASP B . n 
B 2 371 ARG 371 393 393 ARG ARG B . n 
B 2 372 TYR 372 394 394 TYR TYR B . n 
B 2 373 VAL 373 395 395 VAL VAL B . n 
B 2 374 ALA 374 396 396 ALA ALA B . n 
B 2 375 SER 375 397 397 SER SER B . n 
B 2 376 LEU 376 398 398 LEU LEU B . n 
B 2 377 ALA 377 399 399 ALA ALA B . n 
B 2 378 ALA 378 400 400 ALA ALA B . n 
B 2 379 ARG 379 401 401 ARG ARG B . n 
B 2 380 ASN 380 402 402 ASN ASN B . n 
B 2 381 LYS 381 403 403 LYS LYS B . n 
B 2 382 VAL 382 404 404 VAL VAL B . n 
B 2 383 GLY 383 405 405 GLY GLY B . n 
B 2 384 LYS 384 406 406 LYS LYS B . n 
B 2 385 SER 385 407 407 SER SER B . n 
B 2 386 ALA 386 408 408 ALA ALA B . n 
B 2 387 ALA 387 409 409 ALA ALA B . n 
B 2 388 ALA 388 410 410 ALA ALA B . n 
B 2 389 VAL 389 411 411 VAL VAL B . n 
B 2 390 LEU 390 412 412 LEU LEU B . n 
B 2 391 THR 391 413 413 THR THR B . n 
B 2 392 ILE 392 414 414 ILE ILE B . n 
B 2 393 PRO 393 415 415 PRO PRO B . n 
B 2 394 SER 394 416 416 SER SER B . n 
B 2 395 PRO 395 417 417 PRO PRO B . n 
B 2 396 HIS 396 418 418 HIS HIS B . n 
B 2 397 VAL 397 419 419 VAL VAL B . n 
B 2 398 THR 398 420 420 THR THR B . n 
B 2 399 ALA 399 421 421 ALA ALA B . n 
B 2 400 ALA 400 422 422 ALA ALA B . n 
B 2 401 TYR 401 423 423 TYR TYR B . n 
B 2 402 SER 402 424 424 SER SER B . n 
B 2 403 VAL 403 425 425 VAL VAL B . n 
B 2 404 VAL 404 426 426 VAL VAL B . n 
B 2 405 ASN 405 427 427 ASN ASN B . n 
B 2 406 LEU 406 428 428 LEU LEU B . n 
B 2 407 LYS 407 429 429 LYS LYS B . n 
B 2 408 ALA 408 430 430 ALA ALA B . n 
B 2 409 PHE 409 431 431 PHE PHE B . n 
B 2 410 PRO 410 432 432 PRO PRO B . n 
B 2 411 LYS 411 433 433 LYS LYS B . n 
B 2 412 ASP 412 434 434 ASP ASP B . n 
B 2 413 ASN 413 435 435 ASN ASN B . n 
B 2 414 LEU 414 436 436 LEU LEU B . n 
B 2 415 LEU 415 437 437 LEU LEU B . n 
B 2 416 TRP 416 438 438 TRP TRP B . n 
B 2 417 VAL 417 439 439 VAL VAL B . n 
B 2 418 GLU 418 440 440 GLU GLU B . n 
B 2 419 TRP 419 441 441 TRP TRP B . n 
B 2 420 THR 420 442 442 THR THR B . n 
B 2 421 PRO 421 443 443 PRO PRO B . n 
B 2 422 PRO 422 444 444 PRO PRO B . n 
B 2 423 PRO 423 445 445 PRO PRO B . n 
B 2 424 LYS 424 446 446 LYS LYS B . n 
B 2 425 PRO 425 447 447 PRO PRO B . n 
B 2 426 VAL 426 448 448 VAL VAL B . n 
B 2 427 SER 427 449 449 SER SER B . n 
B 2 428 LYS 428 450 450 LYS LYS B . n 
B 2 429 TYR 429 451 451 TYR TYR B . n 
B 2 430 ILE 430 452 452 ILE ILE B . n 
B 2 431 LEU 431 453 453 LEU LEU B . n 
B 2 432 GLU 432 454 454 GLU GLU B . n 
B 2 433 TRP 433 455 455 TRP TRP B . n 
B 2 434 CYS 434 456 456 CYS CYS B . n 
B 2 435 VAL 435 457 457 VAL VAL B . n 
B 2 436 LEU 436 458 458 LEU LEU B . n 
B 2 437 SER 437 459 459 SER SER B . n 
B 2 438 GLU 438 460 460 GLU GLU B . n 
B 2 439 ASN 439 461 461 ASN ASN B . n 
B 2 440 ALA 440 462 462 ALA ALA B . n 
B 2 441 PRO 441 463 463 PRO PRO B . n 
B 2 442 CYS 442 464 464 CYS CYS B . n 
B 2 443 VAL 443 465 465 VAL VAL B . n 
B 2 444 GLU 444 466 466 GLU GLU B . n 
B 2 445 ASP 445 467 467 ASP ASP B . n 
B 2 446 TRP 446 468 468 TRP TRP B . n 
B 2 447 GLN 447 469 469 GLN GLN B . n 
B 2 448 GLN 448 470 470 GLN GLN B . n 
B 2 449 GLU 449 471 471 GLU GLU B . n 
B 2 450 ASP 450 472 472 ASP ASP B . n 
B 2 451 ALA 451 473 473 ALA ALA B . n 
B 2 452 THR 452 474 474 THR THR B . n 
B 2 453 VAL 453 475 475 VAL VAL B . n 
B 2 454 ASN 454 476 476 ASN ASN B . n 
B 2 455 ARG 455 477 477 ARG ARG B . n 
B 2 456 THR 456 478 478 THR THR B . n 
B 2 457 HIS 457 479 479 HIS HIS B . n 
B 2 458 LEU 458 480 480 LEU LEU B . n 
B 2 459 ARG 459 481 481 ARG ARG B . n 
B 2 460 GLY 460 482 482 GLY GLY B . n 
B 2 461 ARG 461 483 483 ARG ARG B . n 
B 2 462 LEU 462 484 484 LEU LEU B . n 
B 2 463 LEU 463 485 485 LEU LEU B . n 
B 2 464 GLU 464 486 486 GLU GLU B . n 
B 2 465 SER 465 487 487 SER SER B . n 
B 2 466 LYS 466 488 488 LYS LYS B . n 
B 2 467 CYS 467 489 489 CYS CYS B . n 
B 2 468 TYR 468 490 490 TYR TYR B . n 
B 2 469 GLN 469 491 491 GLN GLN B . n 
B 2 470 ILE 470 492 492 ILE ILE B . n 
B 2 471 THR 471 493 493 THR THR B . n 
B 2 472 VAL 472 494 494 VAL VAL B . n 
B 2 473 THR 473 495 495 THR THR B . n 
B 2 474 PRO 474 496 496 PRO PRO B . n 
B 2 475 VAL 475 497 497 VAL VAL B . n 
B 2 476 PHE 476 498 498 PHE PHE B . n 
B 2 477 ALA 477 499 499 ALA ALA B . n 
B 2 478 THR 478 500 500 THR THR B . n 
B 2 479 GLY 479 501 501 GLY GLY B . n 
B 2 480 PRO 480 502 502 PRO PRO B . n 
B 2 481 GLY 481 503 503 GLY GLY B . n 
B 2 482 GLY 482 504 504 GLY GLY B . n 
B 2 483 SER 483 505 505 SER SER B . n 
B 2 484 GLU 484 506 506 GLU GLU B . n 
B 2 485 SER 485 507 507 SER SER B . n 
B 2 486 LEU 486 508 508 LEU LEU B . n 
B 2 487 LYS 487 509 509 LYS LYS B . n 
B 2 488 ALA 488 510 510 ALA ALA B . n 
B 2 489 TYR 489 511 511 TYR TYR B . n 
B 2 490 LEU 490 512 512 LEU LEU B . n 
B 2 491 LYS 491 513 513 LYS LYS B . n 
B 2 492 GLN 492 514 514 GLN GLN B . n 
B 2 493 ALA 493 515 515 ALA ALA B . n 
B 2 494 ALA 494 516 516 ALA ALA B . n 
B 2 495 PRO 495 517 517 PRO PRO B . n 
B 2 496 ALA 496 518 518 ALA ALA B . n 
B 2 497 ARG 497 519 519 ARG ARG B . n 
B 2 498 GLY 498 520 520 GLY GLY B . n 
B 2 499 PRO 499 521 521 PRO PRO B . n 
B 2 500 THR 500 522 522 THR THR B . n 
B 2 501 VAL 501 523 523 VAL VAL B . n 
B 2 502 ARG 502 524 524 ARG ARG B . n 
B 2 503 THR 503 525 525 THR THR B . n 
B 2 504 LYS 504 526 526 LYS LYS B . n 
B 2 505 LYS 505 527 527 LYS LYS B . n 
B 2 506 VAL 506 528 528 VAL VAL B . n 
B 2 507 GLY 507 529 529 GLY GLY B . n 
B 2 508 LYS 508 530 530 LYS LYS B . n 
B 2 509 ASN 509 531 531 ASN ASN B . n 
B 2 510 GLU 510 532 532 GLU GLU B . n 
B 2 511 ALA 511 533 533 ALA ALA B . n 
B 2 512 VAL 512 534 534 VAL VAL B . n 
B 2 513 LEU 513 535 535 LEU LEU B . n 
B 2 514 ALA 514 536 536 ALA ALA B . n 
B 2 515 TRP 515 537 537 TRP TRP B . n 
B 2 516 ASP 516 538 538 ASP ASP B . n 
B 2 517 GLN 517 539 539 GLN GLN B . n 
B 2 518 ILE 518 540 540 ILE ILE B . n 
B 2 519 PRO 519 541 541 PRO PRO B . n 
B 2 520 VAL 520 542 542 VAL VAL B . n 
B 2 521 ASP 521 543 543 ASP ASP B . n 
B 2 522 ASP 522 544 544 ASP ASP B . n 
B 2 523 GLN 523 545 545 GLN GLN B . n 
B 2 524 ASN 524 546 546 ASN ASN B . n 
B 2 525 GLY 525 547 547 GLY GLY B . n 
B 2 526 PHE 526 548 548 PHE PHE B . n 
B 2 527 ILE 527 549 549 ILE ILE B . n 
B 2 528 ARG 528 550 550 ARG ARG B . n 
B 2 529 ASN 529 551 551 ASN ASN B . n 
B 2 530 TYR 530 552 552 TYR TYR B . n 
B 2 531 SER 531 553 553 SER SER B . n 
B 2 532 ILE 532 554 554 ILE ILE B . n 
B 2 533 SER 533 555 555 SER SER B . n 
B 2 534 TYR 534 556 556 TYR TYR B . n 
B 2 535 ARG 535 557 557 ARG ARG B . n 
B 2 536 THR 536 558 558 THR THR B . n 
B 2 537 SER 537 559 559 SER SER B . n 
B 2 538 VAL 538 560 560 VAL VAL B . n 
B 2 539 GLY 539 561 561 GLY GLY B . n 
B 2 540 LYS 540 562 562 LYS LYS B . n 
B 2 541 GLU 541 563 563 GLU GLU B . n 
B 2 542 MET 542 564 564 MET MET B . n 
B 2 543 VAL 543 565 565 VAL VAL B . n 
B 2 544 VAL 544 566 566 VAL VAL B . n 
B 2 545 HIS 545 567 567 HIS HIS B . n 
B 2 546 VAL 546 568 568 VAL VAL B . n 
B 2 547 ASP 547 569 569 ASP ASP B . n 
B 2 548 SER 548 570 570 SER SER B . n 
B 2 549 SER 549 571 571 SER SER B . n 
B 2 550 HIS 550 572 572 HIS HIS B . n 
B 2 551 THR 551 573 573 THR THR B . n 
B 2 552 GLU 552 574 574 GLU GLU B . n 
B 2 553 TYR 553 575 575 TYR TYR B . n 
B 2 554 THR 554 576 576 THR THR B . n 
B 2 555 LEU 555 577 577 LEU LEU B . n 
B 2 556 SER 556 578 578 SER SER B . n 
B 2 557 SER 557 579 579 SER SER B . n 
B 2 558 LEU 558 580 580 LEU LEU B . n 
B 2 559 SER 559 581 581 SER SER B . n 
B 2 560 SER 560 582 582 SER SER B . n 
B 2 561 ASP 561 583 583 ASP ASP B . n 
B 2 562 THR 562 584 584 THR THR B . n 
B 2 563 LEU 563 585 585 LEU LEU B . n 
B 2 564 TYR 564 586 586 TYR TYR B . n 
B 2 565 MET 565 587 587 MET MET B . n 
B 2 566 VAL 566 588 588 VAL VAL B . n 
B 2 567 ARG 567 589 589 ARG ARG B . n 
B 2 568 MET 568 590 590 MET MET B . n 
B 2 569 ALA 569 591 591 ALA ALA B . n 
B 2 570 ALA 570 592 592 ALA ALA B . n 
B 2 571 TYR 571 593 593 TYR TYR B . n 
B 2 572 THR 572 594 594 THR THR B . n 
B 2 573 ASP 573 595 595 ASP ASP B . n 
B 2 574 GLU 574 596 596 GLU GLU B . n 
B 2 575 GLY 575 597 597 GLY GLY B . n 
B 2 576 GLY 576 598 598 GLY GLY B . n 
B 2 577 LYS 577 599 599 LYS LYS B . n 
B 2 578 ASP 578 600 600 ASP ASP B . n 
B 2 579 GLY 579 601 601 GLY GLY B . n 
B 2 580 PRO 580 602 602 PRO PRO B . n 
B 2 581 GLU 581 603 603 GLU GLU B . n 
B 2 582 PHE 582 604 604 PHE PHE B . n 
B 2 583 THR 583 605 605 THR THR B . n 
B 2 584 PHE 584 606 606 PHE PHE B . n 
B 2 585 THR 585 607 607 THR THR B . n 
B 2 586 THR 586 608 608 THR THR B . n 
B 2 587 PRO 587 609 609 PRO PRO B . n 
B 2 588 LYS 588 610 ?   ?   ?   B . n 
B 2 589 PHE 589 611 ?   ?   ?   B . n 
B 2 590 ALA 590 612 ?   ?   ?   B . n 
B 2 591 GLN 591 613 ?   ?   ?   B . n 
B 2 592 GLY 592 614 ?   ?   ?   B . n 
B 2 593 GLU 593 615 ?   ?   ?   B . n 
B 2 594 ILE 594 616 ?   ?   ?   B . n 
B 2 595 GLU 595 617 ?   ?   ?   B . n 
B 2 596 GLU 596 618 ?   ?   ?   B . n 
B 2 597 GLN 597 619 ?   ?   ?   B . n 
B 2 598 LYS 598 620 ?   ?   ?   B . n 
B 2 599 LEU 599 621 ?   ?   ?   B . n 
B 2 600 ILE 600 622 ?   ?   ?   B . n 
B 2 601 SER 601 623 ?   ?   ?   B . n 
B 2 602 GLU 602 624 ?   ?   ?   B . n 
B 2 603 GLU 603 625 ?   ?   ?   B . n 
B 2 604 ASP 604 626 ?   ?   ?   B . n 
B 2 605 LEU 605 627 ?   ?   ?   B . n 
B 2 606 GLY 606 628 ?   ?   ?   B . n 
B 2 607 GLY 607 629 ?   ?   ?   B . n 
B 2 608 GLU 608 630 ?   ?   ?   B . n 
B 2 609 GLN 609 631 ?   ?   ?   B . n 
B 2 610 LYS 610 632 ?   ?   ?   B . n 
B 2 611 LEU 611 633 ?   ?   ?   B . n 
B 2 612 ILE 612 634 ?   ?   ?   B . n 
B 2 613 SER 613 635 ?   ?   ?   B . n 
B 2 614 GLU 614 636 ?   ?   ?   B . n 
B 2 615 GLU 615 637 ?   ?   ?   B . n 
B 2 616 ASP 616 638 ?   ?   ?   B . n 
B 2 617 LEU 617 639 ?   ?   ?   B . n 
B 2 618 HIS 618 640 ?   ?   ?   B . n 
B 2 619 HIS 619 641 ?   ?   ?   B . n 
B 2 620 HIS 620 642 ?   ?   ?   B . n 
B 2 621 HIS 621 643 ?   ?   ?   B . n 
B 2 622 HIS 622 644 ?   ?   ?   B . n 
B 2 623 HIS 623 645 ?   ?   ?   B . n 
C 3 1   GLU 1   24  ?   ?   ?   C . n 
C 3 2   VAL 2   25  ?   ?   ?   C . n 
C 3 3   LEU 3   26  ?   ?   ?   C . n 
C 3 4   GLU 4   27  ?   ?   ?   C . n 
C 3 5   GLU 5   28  ?   ?   ?   C . n 
C 3 6   PRO 6   29  29  PRO PRO C . n 
C 3 7   LEU 7   30  30  LEU LEU C . n 
C 3 8   PRO 8   31  31  PRO PRO C . n 
C 3 9   LEU 9   32  32  LEU LEU C . n 
C 3 10  THR 10  33  33  THR THR C . n 
C 3 11  PRO 11  34  34  PRO PRO C . n 
C 3 12  GLU 12  35  35  GLU GLU C . n 
C 3 13  ILE 13  36  36  ILE ILE C . n 
C 3 14  HIS 14  37  37  HIS HIS C . n 
C 3 15  LYS 15  38  38  LYS LYS C . n 
C 3 16  VAL 16  39  39  VAL VAL C . n 
C 3 17  SER 17  40  40  SER SER C . n 
C 3 18  PHE 18  41  41  PHE PHE C . n 
C 3 19  GLN 19  42  42  GLN GLN C . n 
C 3 20  LEU 20  43  43  LEU LEU C . n 
C 3 21  LYS 21  44  44  LYS LYS C . n 
C 3 22  LEU 22  45  45  LEU LEU C . n 
C 3 23  GLN 23  46  46  GLN GLN C . n 
C 3 24  GLU 24  47  47  GLU GLU C . n 
C 3 25  VAL 25  48  48  VAL VAL C . n 
C 3 26  ASN 26  49  49  ASN ASN C . n 
C 3 27  LEU 27  50  50  LEU LEU C . n 
C 3 28  GLU 28  51  51  GLU GLU C . n 
C 3 29  TRP 29  52  52  TRP TRP C . n 
C 3 30  THR 30  53  53  THR THR C . n 
C 3 31  VAL 31  54  54  VAL VAL C . n 
C 3 32  PRO 32  55  55  PRO PRO C . n 
C 3 33  ALA 33  56  56  ALA ALA C . n 
C 3 34  LEU 34  57  57  LEU LEU C . n 
C 3 35  THR 35  58  58  THR THR C . n 
C 3 36  HIS 36  59  59  HIS HIS C . n 
C 3 37  GLU 37  60  60  GLU GLU C . n 
C 3 38  GLU 38  61  61  GLU GLU C . n 
C 3 39  LEU 39  62  62  LEU LEU C . n 
C 3 40  ASN 40  63  63  ASN ASN C . n 
C 3 41  MET 41  64  64  MET MET C . n 
C 3 42  ILE 42  65  65  ILE ILE C . n 
C 3 43  PHE 43  66  66  PHE PHE C . n 
C 3 44  GLN 44  67  67  GLN GLN C . n 
C 3 45  ILE 45  68  68  ILE ILE C . n 
C 3 46  GLU 46  69  69  GLU GLU C . n 
C 3 47  ILE 47  70  70  ILE ILE C . n 
C 3 48  SER 48  71  71  SER SER C . n 
C 3 49  ARG 49  72  72  ARG ARG C . n 
C 3 50  LEU 50  73  73  LEU LEU C . n 
C 3 51  ASN 51  74  74  ASN ASN C . n 
C 3 52  ILE 52  75  75  ILE ILE C . n 
C 3 53  SER 53  76  76  SER SER C . n 
C 3 54  ASN 54  77  77  ASN ASN C . n 
C 3 55  THR 55  78  78  THR THR C . n 
C 3 56  ILE 56  79  79  ILE ILE C . n 
C 3 57  TRP 57  80  80  TRP TRP C . n 
C 3 58  VAL 58  81  81  VAL VAL C . n 
C 3 59  GLU 59  82  82  GLU GLU C . n 
C 3 60  ASN 60  83  83  ASN ASN C . n 
C 3 61  TYR 61  84  84  TYR TYR C . n 
C 3 62  SER 62  85  85  SER SER C . n 
C 3 63  THR 63  86  86  THR THR C . n 
C 3 64  THR 64  87  87  THR THR C . n 
C 3 65  VAL 65  88  88  VAL VAL C . n 
C 3 66  LYS 66  89  89  LYS LYS C . n 
C 3 67  ARG 67  90  90  ARG ARG C . n 
C 3 68  GLU 68  91  91  GLU GLU C . n 
C 3 69  GLU 69  92  92  GLU GLU C . n 
C 3 70  ALA 70  93  93  ALA ALA C . n 
C 3 71  VAL 71  94  94  VAL VAL C . n 
C 3 72  ARG 72  95  95  ARG ARG C . n 
C 3 73  TRP 73  96  96  TRP TRP C . n 
C 3 74  ASN 74  97  97  ASN ASN C . n 
C 3 75  TRP 75  98  98  TRP TRP C . n 
C 3 76  THR 76  99  99  THR THR C . n 
C 3 77  SER 77  100 100 SER SER C . n 
C 3 78  ASP 78  101 101 ASP ASP C . n 
C 3 79  ILE 79  102 102 ILE ILE C . n 
C 3 80  PRO 80  103 103 PRO PRO C . n 
C 3 81  LEU 81  104 104 LEU LEU C . n 
C 3 82  GLU 82  105 105 GLU GLU C . n 
C 3 83  CYS 83  106 106 CYS CYS C . n 
C 3 84  VAL 84  107 107 VAL VAL C . n 
C 3 85  LYS 85  108 108 LYS LYS C . n 
C 3 86  HIS 86  109 109 HIS HIS C . n 
C 3 87  PHE 87  110 110 PHE PHE C . n 
C 3 88  ILE 88  111 111 ILE ILE C . n 
C 3 89  ARG 89  112 112 ARG ARG C . n 
C 3 90  ILE 90  113 113 ILE ILE C . n 
C 3 91  ARG 91  114 114 ARG ARG C . n 
C 3 92  ALA 92  115 115 ALA ALA C . n 
C 3 93  LEU 93  116 116 LEU LEU C . n 
C 3 94  VAL 94  117 117 VAL VAL C . n 
C 3 95  ASP 95  118 118 ASP ASP C . n 
C 3 96  ASP 96  119 119 ASP ASP C . n 
C 3 97  THR 97  120 120 THR THR C . n 
C 3 98  LYS 98  121 121 LYS LYS C . n 
C 3 99  SER 99  122 122 SER SER C . n 
C 3 100 LEU 100 123 123 LEU LEU C . n 
C 3 101 PRO 101 124 124 PRO PRO C . n 
C 3 102 GLN 102 125 125 GLN GLN C . n 
C 3 103 SER 103 126 126 SER SER C . n 
C 3 104 SER 104 127 127 SER SER C . n 
C 3 105 TRP 105 128 128 TRP TRP C . n 
C 3 106 GLY 106 129 129 GLY GLY C . n 
C 3 107 ASN 107 130 130 ASN ASN C . n 
C 3 108 TRP 108 131 131 TRP TRP C . n 
C 3 109 SER 109 132 132 SER SER C . n 
C 3 110 SER 110 133 133 SER SER C . n 
C 3 111 TRP 111 134 134 TRP TRP C . n 
C 3 112 LYS 112 135 135 LYS LYS C . n 
C 3 113 GLU 113 136 136 GLU GLU C . n 
C 3 114 VAL 114 137 137 VAL VAL C . n 
C 3 115 ASN 115 138 138 ASN ASN C . n 
C 3 116 ALA 116 139 139 ALA ALA C . n 
C 3 117 LYS 117 140 140 LYS LYS C . n 
C 3 118 VAL 118 141 141 VAL VAL C . n 
C 3 119 SER 119 142 142 SER SER C . n 
C 3 120 VAL 120 143 143 VAL VAL C . n 
C 3 121 GLU 121 144 144 GLU GLU C . n 
C 3 122 PRO 122 145 145 PRO PRO C . n 
C 3 123 ASP 123 146 146 ASP ASP C . n 
C 3 124 LYS 124 147 147 LYS LYS C . n 
C 3 125 SER 125 148 148 SER SER C . n 
C 3 126 LEU 126 149 149 LEU LEU C . n 
C 3 127 ILE 127 150 150 ILE ILE C . n 
C 3 128 PHE 128 151 151 PHE PHE C . n 
C 3 129 PRO 129 152 152 PRO PRO C . n 
C 3 130 LYS 130 153 153 LYS LYS C . n 
C 3 131 ASP 131 154 154 ASP ASP C . n 
C 3 132 LYS 132 155 155 LYS LYS C . n 
C 3 133 VAL 133 156 156 VAL VAL C . n 
C 3 134 LEU 134 157 157 LEU LEU C . n 
C 3 135 GLU 135 158 158 GLU GLU C . n 
C 3 136 GLU 136 159 159 GLU GLU C . n 
C 3 137 GLY 137 160 160 GLY GLY C . n 
C 3 138 SER 138 161 161 SER SER C . n 
C 3 139 ASN 139 162 162 ASN ASN C . n 
C 3 140 VAL 140 163 163 VAL VAL C . n 
C 3 141 THR 141 164 164 THR THR C . n 
C 3 142 ILE 142 165 165 ILE ILE C . n 
C 3 143 CYS 143 166 166 CYS CYS C . n 
C 3 144 LEU 144 167 167 LEU LEU C . n 
C 3 145 MET 145 168 168 MET MET C . n 
C 3 146 TYR 146 169 169 TYR TYR C . n 
C 3 147 GLY 147 170 170 GLY GLY C . n 
C 3 148 GLN 148 171 171 GLN GLN C . n 
C 3 149 ASN 149 172 172 ASN ASN C . n 
C 3 150 VAL 150 173 173 VAL VAL C . n 
C 3 151 TYR 151 174 174 TYR TYR C . n 
C 3 152 ASN 152 175 175 ASN ASN C . n 
C 3 153 VAL 153 176 176 VAL VAL C . n 
C 3 154 SER 154 177 177 SER SER C . n 
C 3 155 CYS 155 178 178 CYS CYS C . n 
C 3 156 LYS 156 179 179 LYS LYS C . n 
C 3 157 LEU 157 180 180 LEU LEU C . n 
C 3 158 GLN 158 181 181 GLN GLN C . n 
C 3 159 ASP 159 182 182 ASP ASP C . n 
C 3 160 GLU 160 183 183 GLU GLU C . n 
C 3 161 PRO 161 184 184 PRO PRO C . n 
C 3 162 ILE 162 185 185 ILE ILE C . n 
C 3 163 HIS 163 186 186 HIS HIS C . n 
C 3 164 GLY 164 187 187 GLY GLY C . n 
C 3 165 GLU 165 188 188 GLU GLU C . n 
C 3 166 GLN 166 189 189 GLN GLN C . n 
C 3 167 LEU 167 190 190 LEU LEU C . n 
C 3 168 ASP 168 191 191 ASP ASP C . n 
C 3 169 SER 169 192 192 SER SER C . n 
C 3 170 HIS 170 193 193 HIS HIS C . n 
C 3 171 VAL 171 194 194 VAL VAL C . n 
C 3 172 SER 172 195 195 SER SER C . n 
C 3 173 LEU 173 196 196 LEU LEU C . n 
C 3 174 LEU 174 197 197 LEU LEU C . n 
C 3 175 LYS 175 198 198 LYS LYS C . n 
C 3 176 LEU 176 199 199 LEU LEU C . n 
C 3 177 ASN 177 200 200 ASN ASN C . n 
C 3 178 ASN 178 201 201 ASN ASN C . n 
C 3 179 VAL 179 202 202 VAL VAL C . n 
C 3 180 VAL 180 203 203 VAL VAL C . n 
C 3 181 PHE 181 204 204 PHE PHE C . n 
C 3 182 LEU 182 205 205 LEU LEU C . n 
C 3 183 SER 183 206 206 SER SER C . n 
C 3 184 ASP 184 207 207 ASP ASP C . n 
C 3 185 THR 185 208 208 THR THR C . n 
C 3 186 GLY 186 209 209 GLY GLY C . n 
C 3 187 THR 187 210 210 THR THR C . n 
C 3 188 ASN 188 211 211 ASN ASN C . n 
C 3 189 ILE 189 212 212 ILE ILE C . n 
C 3 190 ASN 190 213 213 ASN ASN C . n 
C 3 191 CYS 191 214 214 CYS CYS C . n 
C 3 192 GLN 192 215 215 GLN GLN C . n 
C 3 193 ALA 193 216 216 ALA ALA C . n 
C 3 194 THR 194 217 217 THR THR C . n 
C 3 195 LYS 195 218 218 LYS LYS C . n 
C 3 196 GLY 196 219 219 GLY GLY C . n 
C 3 197 PRO 197 220 220 PRO PRO C . n 
C 3 198 LYS 198 221 221 LYS LYS C . n 
C 3 199 ARG 199 222 222 ARG ARG C . n 
C 3 200 ILE 200 223 223 ILE ILE C . n 
C 3 201 PHE 201 224 224 PHE PHE C . n 
C 3 202 GLY 202 225 225 GLY GLY C . n 
C 3 203 THR 203 226 226 THR THR C . n 
C 3 204 VAL 204 227 227 VAL VAL C . n 
C 3 205 LEU 205 228 228 LEU LEU C . n 
C 3 206 PHE 206 229 229 PHE PHE C . n 
C 3 207 VAL 207 230 230 VAL VAL C . n 
C 3 208 SER 208 231 231 SER SER C . n 
C 3 209 LYS 209 232 232 LYS LYS C . n 
C 3 210 VAL 210 233 233 VAL VAL C . n 
C 3 211 LEU 211 234 234 LEU LEU C . n 
C 3 212 GLU 212 235 235 GLU GLU C . n 
C 3 213 GLU 213 236 236 GLU GLU C . n 
C 3 214 PRO 214 237 237 PRO PRO C . n 
C 3 215 LYS 215 238 238 LYS LYS C . n 
C 3 216 ASN 216 239 239 ASN ASN C . n 
C 3 217 VAL 217 240 240 VAL VAL C . n 
C 3 218 SER 218 241 241 SER SER C . n 
C 3 219 CYS 219 242 242 CYS CYS C . n 
C 3 220 GLU 220 243 243 GLU GLU C . n 
C 3 221 THR 221 244 244 THR THR C . n 
C 3 222 ARG 222 245 245 ARG ARG C . n 
C 3 223 ASP 223 246 246 ASP ASP C . n 
C 3 224 PHE 224 247 247 PHE PHE C . n 
C 3 225 LYS 225 248 248 LYS LYS C . n 
C 3 226 THR 226 249 249 THR THR C . n 
C 3 227 LEU 227 250 250 LEU LEU C . n 
C 3 228 ASP 228 251 251 ASP ASP C . n 
C 3 229 CYS 229 252 252 CYS CYS C . n 
C 3 230 SER 230 253 253 SER SER C . n 
C 3 231 TRP 231 254 254 TRP TRP C . n 
C 3 232 GLU 232 255 255 GLU GLU C . n 
C 3 233 PRO 233 256 256 PRO PRO C . n 
C 3 234 GLY 234 257 257 GLY GLY C . n 
C 3 235 VAL 235 258 258 VAL VAL C . n 
C 3 236 ASP 236 259 259 ASP ASP C . n 
C 3 237 THR 237 260 260 THR THR C . n 
C 3 238 THR 238 261 261 THR THR C . n 
C 3 239 LEU 239 262 262 LEU LEU C . n 
C 3 240 THR 240 263 263 THR THR C . n 
C 3 241 TRP 241 264 264 TRP TRP C . n 
C 3 242 ARG 242 265 265 ARG ARG C . n 
C 3 243 LYS 243 266 266 LYS LYS C . n 
C 3 244 GLN 244 267 267 GLN GLN C . n 
C 3 245 ARG 245 268 268 ARG ARG C . n 
C 3 246 PHE 246 269 269 PHE PHE C . n 
C 3 247 GLN 247 270 270 GLN GLN C . n 
C 3 248 ASN 248 271 271 ASN ASN C . n 
C 3 249 TYR 249 272 272 TYR TYR C . n 
C 3 250 THR 250 273 273 THR THR C . n 
C 3 251 LEU 251 274 274 LEU LEU C . n 
C 3 252 CYS 252 275 275 CYS CYS C . n 
C 3 253 GLU 253 276 276 GLU GLU C . n 
C 3 254 SER 254 277 277 SER SER C . n 
C 3 255 PHE 255 278 278 PHE PHE C . n 
C 3 256 SER 256 279 279 SER SER C . n 
C 3 257 LYS 257 280 280 LYS LYS C . n 
C 3 258 ARG 258 281 281 ARG ARG C . n 
C 3 259 CYS 259 282 282 CYS CYS C . n 
C 3 260 GLU 260 283 283 GLU GLU C . n 
C 3 261 VAL 261 284 284 VAL VAL C . n 
C 3 262 SER 262 285 285 SER SER C . n 
C 3 263 ASN 263 286 286 ASN ASN C . n 
C 3 264 TYR 264 287 287 TYR TYR C . n 
C 3 265 ARG 265 288 288 ARG ARG C . n 
C 3 266 ASN 266 289 289 ASN ASN C . n 
C 3 267 SER 267 290 290 SER SER C . n 
C 3 268 TYR 268 291 291 TYR TYR C . n 
C 3 269 THR 269 292 292 THR THR C . n 
C 3 270 TRP 270 293 293 TRP TRP C . n 
C 3 271 GLN 271 294 294 GLN GLN C . n 
C 3 272 ILE 272 295 295 ILE ILE C . n 
C 3 273 THR 273 296 296 THR THR C . n 
C 3 274 GLU 274 297 297 GLU GLU C . n 
C 3 275 GLY 275 298 298 GLY GLY C . n 
C 3 276 SER 276 299 299 SER SER C . n 
C 3 277 GLN 277 300 300 GLN GLN C . n 
C 3 278 GLU 278 301 301 GLU GLU C . n 
C 3 279 MET 279 302 302 MET MET C . n 
C 3 280 TYR 280 303 303 TYR TYR C . n 
C 3 281 ASN 281 304 304 ASN ASN C . n 
C 3 282 PHE 282 305 305 PHE PHE C . n 
C 3 283 THR 283 306 306 THR THR C . n 
C 3 284 LEU 284 307 307 LEU LEU C . n 
C 3 285 THR 285 308 308 THR THR C . n 
C 3 286 ALA 286 309 309 ALA ALA C . n 
C 3 287 GLU 287 310 310 GLU GLU C . n 
C 3 288 ASN 288 311 311 ASN ASN C . n 
C 3 289 GLN 289 312 312 GLN GLN C . n 
C 3 290 LEU 290 313 313 LEU LEU C . n 
C 3 291 ARG 291 314 314 ARG ARG C . n 
C 3 292 LYS 292 315 315 LYS LYS C . n 
C 3 293 ARG 293 316 316 ARG ARG C . n 
C 3 294 SER 294 317 317 SER SER C . n 
C 3 295 VAL 295 318 318 VAL VAL C . n 
C 3 296 ASN 296 319 319 ASN ASN C . n 
C 3 297 ILE 297 320 320 ILE ILE C . n 
C 3 298 ASN 298 321 321 ASN ASN C . n 
C 3 299 PHE 299 322 322 PHE PHE C . n 
C 3 300 ASN 300 323 323 ASN ASN C . n 
C 3 301 LEU 301 324 324 LEU LEU C . n 
C 3 302 THR 302 325 325 THR THR C . n 
C 3 303 HIS 303 326 326 HIS HIS C . n 
C 3 304 ARG 304 327 327 ARG ARG C . n 
C 3 305 VAL 305 328 328 VAL VAL C . n 
C 3 306 HIS 306 329 329 HIS HIS C . n 
C 3 307 PRO 307 330 330 PRO PRO C . n 
C 3 308 LYS 308 331 331 LYS LYS C . n 
C 3 309 ALA 309 332 332 ALA ALA C . n 
C 3 310 PRO 310 333 333 PRO PRO C . n 
C 3 311 GLN 311 334 334 GLN GLN C . n 
C 3 312 ASP 312 335 335 ASP ASP C . n 
C 3 313 VAL 313 336 336 VAL VAL C . n 
C 3 314 THR 314 337 337 THR THR C . n 
C 3 315 LEU 315 338 338 LEU LEU C . n 
C 3 316 LYS 316 339 339 LYS LYS C . n 
C 3 317 ILE 317 340 340 ILE ILE C . n 
C 3 318 ILE 318 341 341 ILE ILE C . n 
C 3 319 GLY 319 342 342 GLY GLY C . n 
C 3 320 ALA 320 343 343 ALA ALA C . n 
C 3 321 THR 321 344 344 THR THR C . n 
C 3 322 LYS 322 345 345 LYS LYS C . n 
C 3 323 ALA 323 346 346 ALA ALA C . n 
C 3 324 ASN 324 347 347 ASN ASN C . n 
C 3 325 MET 325 348 348 MET MET C . n 
C 3 326 THR 326 349 349 THR THR C . n 
C 3 327 TRP 327 350 350 TRP TRP C . n 
C 3 328 LYS 328 351 351 LYS LYS C . n 
C 3 329 VAL 329 352 352 VAL VAL C . n 
C 3 330 HIS 330 353 353 HIS HIS C . n 
C 3 331 SER 331 354 354 SER SER C . n 
C 3 332 HIS 332 355 355 HIS HIS C . n 
C 3 333 GLY 333 356 356 GLY GLY C . n 
C 3 334 ASN 334 357 357 ASN ASN C . n 
C 3 335 ASN 335 358 358 ASN ASN C . n 
C 3 336 TYR 336 359 359 TYR TYR C . n 
C 3 337 THR 337 360 360 THR THR C . n 
C 3 338 LEU 338 361 361 LEU LEU C . n 
C 3 339 LEU 339 362 362 LEU LEU C . n 
C 3 340 CYS 340 363 363 CYS CYS C . n 
C 3 341 GLN 341 364 364 GLN GLN C . n 
C 3 342 VAL 342 365 365 VAL VAL C . n 
C 3 343 LYS 343 366 366 LYS LYS C . n 
C 3 344 LEU 344 367 367 LEU LEU C . n 
C 3 345 GLN 345 368 368 GLN GLN C . n 
C 3 346 TYR 346 369 369 TYR TYR C . n 
C 3 347 GLY 347 370 370 GLY GLY C . n 
C 3 348 GLU 348 371 371 GLU GLU C . n 
C 3 349 VAL 349 372 372 VAL VAL C . n 
C 3 350 ILE 350 373 373 ILE ILE C . n 
C 3 351 HIS 351 374 374 HIS HIS C . n 
C 3 352 GLU 352 375 375 GLU GLU C . n 
C 3 353 HIS 353 376 376 HIS HIS C . n 
C 3 354 ASN 354 377 377 ASN ASN C . n 
C 3 355 VAL 355 378 378 VAL VAL C . n 
C 3 356 SER 356 379 379 SER SER C . n 
C 3 357 VAL 357 380 380 VAL VAL C . n 
C 3 358 HIS 358 381 381 HIS HIS C . n 
C 3 359 MET 359 382 382 MET MET C . n 
C 3 360 SER 360 383 383 SER SER C . n 
C 3 361 ALA 361 384 384 ALA ALA C . n 
C 3 362 ASN 362 385 385 ASN ASN C . n 
C 3 363 TYR 363 386 386 TYR TYR C . n 
C 3 364 LEU 364 387 387 LEU LEU C . n 
C 3 365 PHE 365 388 388 PHE PHE C . n 
C 3 366 SER 366 389 389 SER SER C . n 
C 3 367 ASP 367 390 390 ASP ASP C . n 
C 3 368 LEU 368 391 391 LEU LEU C . n 
C 3 369 ASP 369 392 392 ASP ASP C . n 
C 3 370 PRO 370 393 393 PRO PRO C . n 
C 3 371 ASP 371 394 394 ASP ASP C . n 
C 3 372 THR 372 395 395 THR THR C . n 
C 3 373 LYS 373 396 396 LYS LYS C . n 
C 3 374 TYR 374 397 397 TYR TYR C . n 
C 3 375 LYS 375 398 398 LYS LYS C . n 
C 3 376 ALA 376 399 399 ALA ALA C . n 
C 3 377 PHE 377 400 400 PHE PHE C . n 
C 3 378 VAL 378 401 401 VAL VAL C . n 
C 3 379 ARG 379 402 402 ARG ARG C . n 
C 3 380 CYS 380 403 403 CYS CYS C . n 
C 3 381 ALA 381 404 404 ALA ALA C . n 
C 3 382 SER 382 405 405 SER SER C . n 
C 3 383 ALA 383 406 406 ALA ALA C . n 
C 3 384 ASN 384 407 407 ASN ASN C . n 
C 3 385 HIS 385 408 408 HIS HIS C . n 
C 3 386 PHE 386 409 409 PHE PHE C . n 
C 3 387 TRP 387 410 410 TRP TRP C . n 
C 3 388 LYS 388 411 411 LYS LYS C . n 
C 3 389 TRP 389 412 412 TRP TRP C . n 
C 3 390 SER 390 413 413 SER SER C . n 
C 3 391 ASP 391 414 414 ASP ASP C . n 
C 3 392 TRP 392 415 415 TRP TRP C . n 
C 3 393 THR 393 416 416 THR THR C . n 
C 3 394 GLN 394 417 417 GLN GLN C . n 
C 3 395 LYS 395 418 418 LYS LYS C . n 
C 3 396 GLU 396 419 419 GLU GLU C . n 
C 3 397 PHE 397 420 420 PHE PHE C . n 
C 3 398 SER 398 421 421 SER SER C . n 
C 3 399 THR 399 422 422 THR THR C . n 
C 3 400 PRO 400 423 423 PRO PRO C . n 
C 3 401 GLU 401 424 424 GLU GLU C . n 
C 3 402 THR 402 425 425 THR THR C . n 
C 3 403 ALA 403 426 426 ALA ALA C . n 
C 3 404 PRO 404 427 427 PRO PRO C . n 
C 3 405 SER 405 428 428 SER SER C . n 
C 3 406 GLN 406 429 429 GLN GLN C . n 
C 3 407 ALA 407 430 430 ALA ALA C . n 
C 3 408 LEU 408 431 431 LEU LEU C . n 
C 3 409 ASP 409 432 432 ASP ASP C . n 
C 3 410 VAL 410 433 433 VAL VAL C . n 
C 3 411 TRP 411 434 434 TRP TRP C . n 
C 3 412 ARG 412 435 435 ARG ARG C . n 
C 3 413 GLN 413 436 436 GLN GLN C . n 
C 3 414 VAL 414 437 437 VAL VAL C . n 
C 3 415 TRP 415 438 438 TRP TRP C . n 
C 3 416 SER 416 439 439 SER SER C . n 
C 3 417 GLU 417 440 440 GLU GLU C . n 
C 3 418 ASN 418 441 441 ASN ASN C . n 
C 3 419 GLY 419 442 442 GLY GLY C . n 
C 3 420 ARG 420 443 443 ARG ARG C . n 
C 3 421 ARG 421 444 444 ARG ARG C . n 
C 3 422 ILE 422 445 445 ILE ILE C . n 
C 3 423 VAL 423 446 446 VAL VAL C . n 
C 3 424 THR 424 447 447 THR THR C . n 
C 3 425 LEU 425 448 448 LEU LEU C . n 
C 3 426 PHE 426 449 449 PHE PHE C . n 
C 3 427 TRP 427 450 450 TRP TRP C . n 
C 3 428 LYS 428 451 451 LYS LYS C . n 
C 3 429 PRO 429 452 452 PRO PRO C . n 
C 3 430 LEU 430 453 453 LEU LEU C . n 
C 3 431 LEU 431 454 454 LEU LEU C . n 
C 3 432 LYS 432 455 455 LYS LYS C . n 
C 3 433 SER 433 456 456 SER SER C . n 
C 3 434 GLN 434 457 457 GLN GLN C . n 
C 3 435 ALA 435 458 458 ALA ALA C . n 
C 3 436 ASN 436 459 459 ASN ASN C . n 
C 3 437 GLY 437 460 460 GLY GLY C . n 
C 3 438 LYS 438 461 461 LYS LYS C . n 
C 3 439 ILE 439 462 462 ILE ILE C . n 
C 3 440 ILE 440 463 463 ILE ILE C . n 
C 3 441 SER 441 464 464 SER SER C . n 
C 3 442 TYR 442 465 465 TYR TYR C . n 
C 3 443 ASN 443 466 466 ASN ASN C . n 
C 3 444 ILE 444 467 467 ILE ILE C . n 
C 3 445 VAL 445 468 468 VAL VAL C . n 
C 3 446 VAL 446 469 469 VAL VAL C . n 
C 3 447 GLU 447 470 470 GLU GLU C . n 
C 3 448 ASN 448 471 471 ASN ASN C . n 
C 3 449 GLU 449 472 472 GLU GLU C . n 
C 3 450 ALA 450 473 473 ALA ALA C . n 
C 3 451 LYS 451 474 474 LYS LYS C . n 
C 3 452 PRO 452 475 475 PRO PRO C . n 
C 3 453 THR 453 476 476 THR THR C . n 
C 3 454 GLU 454 477 477 GLU GLU C . n 
C 3 455 SER 455 478 478 SER SER C . n 
C 3 456 GLU 456 479 479 GLU GLU C . n 
C 3 457 HIS 457 480 480 HIS HIS C . n 
C 3 458 TYR 458 481 481 TYR TYR C . n 
C 3 459 CYS 459 482 482 CYS CYS C . n 
C 3 460 VAL 460 483 483 VAL VAL C . n 
C 3 461 TRP 461 484 484 TRP TRP C . n 
C 3 462 ALA 462 485 485 ALA ALA C . n 
C 3 463 PRO 463 486 486 PRO PRO C . n 
C 3 464 ALA 464 487 487 ALA ALA C . n 
C 3 465 LEU 465 488 488 LEU LEU C . n 
C 3 466 SER 466 489 489 SER SER C . n 
C 3 467 THR 467 490 490 THR THR C . n 
C 3 468 ASN 468 491 491 ASN ASN C . n 
C 3 469 LEU 469 492 492 LEU LEU C . n 
C 3 470 SER 470 493 493 SER SER C . n 
C 3 471 LEU 471 494 494 LEU LEU C . n 
C 3 472 ASP 472 495 495 ASP ASP C . n 
C 3 473 LEU 473 496 496 LEU LEU C . n 
C 3 474 GLN 474 497 497 GLN GLN C . n 
C 3 475 PRO 475 498 498 PRO PRO C . n 
C 3 476 TYR 476 499 499 TYR TYR C . n 
C 3 477 LYS 477 500 500 LYS LYS C . n 
C 3 478 ILE 478 501 501 ILE ILE C . n 
C 3 479 ARG 479 502 502 ARG ARG C . n 
C 3 480 ILE 480 503 503 ILE ILE C . n 
C 3 481 THR 481 504 504 THR THR C . n 
C 3 482 THR 482 505 505 THR THR C . n 
C 3 483 ASN 483 506 506 ASN ASN C . n 
C 3 484 ASN 484 507 507 ASN ASN C . n 
C 3 485 SER 485 508 508 SER SER C . n 
C 3 486 MET 486 509 509 MET MET C . n 
C 3 487 GLY 487 510 510 GLY GLY C . n 
C 3 488 ALA 488 511 511 ALA ALA C . n 
C 3 489 SER 489 512 512 SER SER C . n 
C 3 490 PRO 490 513 513 PRO PRO C . n 
C 3 491 GLU 491 514 514 GLU GLU C . n 
C 3 492 SER 492 515 515 SER SER C . n 
C 3 493 LEU 493 516 516 LEU LEU C . n 
C 3 494 MET 494 517 517 MET MET C . n 
C 3 495 VAL 495 518 518 VAL VAL C . n 
C 3 496 LEU 496 519 519 LEU LEU C . n 
C 3 497 SER 497 520 520 SER SER C . n 
C 3 498 ASN 498 521 521 ASN ASN C . n 
C 3 499 ASP 499 522 522 ASP ASP C . n 
C 3 500 SER 500 523 523 SER SER C . n 
C 3 501 GLY 501 524 524 GLY GLY C . n 
C 3 502 HIS 502 525 525 HIS HIS C . n 
C 3 503 GLU 503 526 526 GLU GLU C . n 
C 3 504 GLU 504 527 527 GLU GLU C . n 
C 3 505 VAL 505 528 528 VAL VAL C . n 
C 3 506 LYS 506 529 529 LYS LYS C . n 
C 3 507 GLU 507 530 530 GLU GLU C . n 
C 3 508 LYS 508 531 531 LYS LYS C . n 
C 3 509 THR 509 532 532 THR THR C . n 
C 3 510 ILE 510 533 533 ILE ILE C . n 
C 3 511 LYS 511 534 534 LYS LYS C . n 
C 3 512 GLY 512 535 535 GLY GLY C . n 
C 3 513 ILE 513 536 536 ILE ILE C . n 
C 3 514 LYS 514 537 537 LYS LYS C . n 
C 3 515 ASP 515 538 538 ASP ASP C . n 
C 3 516 ALA 516 539 539 ALA ALA C . n 
C 3 517 PHE 517 540 540 PHE PHE C . n 
C 3 518 ASN 518 541 541 ASN ASN C . n 
C 3 519 ILE 519 542 542 ILE ILE C . n 
C 3 520 SER 520 543 543 SER SER C . n 
C 3 521 TRP 521 544 544 TRP TRP C . n 
C 3 522 GLU 522 545 545 GLU GLU C . n 
C 3 523 PRO 523 546 546 PRO PRO C . n 
C 3 524 VAL 524 547 547 VAL VAL C . n 
C 3 525 SER 525 548 548 SER SER C . n 
C 3 526 GLY 526 549 549 GLY GLY C . n 
C 3 527 ASP 527 550 550 ASP ASP C . n 
C 3 528 THR 528 551 551 THR THR C . n 
C 3 529 MET 529 552 552 MET MET C . n 
C 3 530 GLY 530 553 553 GLY GLY C . n 
C 3 531 TYR 531 554 554 TYR TYR C . n 
C 3 532 VAL 532 555 555 VAL VAL C . n 
C 3 533 VAL 533 556 556 VAL VAL C . n 
C 3 534 ASP 534 557 557 ASP ASP C . n 
C 3 535 TRP 535 558 558 TRP TRP C . n 
C 3 536 CYS 536 559 559 CYS CYS C . n 
C 3 537 ALA 537 560 560 ALA ALA C . n 
C 3 538 HIS 538 561 561 HIS HIS C . n 
C 3 539 SER 539 562 562 SER SER C . n 
C 3 540 GLN 540 563 563 GLN GLN C . n 
C 3 541 ASP 541 564 564 ASP ASP C . n 
C 3 542 GLN 542 565 565 GLN GLN C . n 
C 3 543 ARG 543 566 566 ARG ARG C . n 
C 3 544 CYS 544 567 567 CYS CYS C . n 
C 3 545 ASP 545 568 568 ASP ASP C . n 
C 3 546 LEU 546 569 569 LEU LEU C . n 
C 3 547 GLN 547 570 570 GLN GLN C . n 
C 3 548 TRP 548 571 571 TRP TRP C . n 
C 3 549 LYS 549 572 572 LYS LYS C . n 
C 3 550 ASN 550 573 573 ASN ASN C . n 
C 3 551 LEU 551 574 574 LEU LEU C . n 
C 3 552 GLY 552 575 575 GLY GLY C . n 
C 3 553 PRO 553 576 576 PRO PRO C . n 
C 3 554 ASN 554 577 577 ASN ASN C . n 
C 3 555 THR 555 578 578 THR THR C . n 
C 3 556 THR 556 579 579 THR THR C . n 
C 3 557 SER 557 580 580 SER SER C . n 
C 3 558 THR 558 581 581 THR THR C . n 
C 3 559 THR 559 582 582 THR THR C . n 
C 3 560 ILE 560 583 583 ILE ILE C . n 
C 3 561 THR 561 584 584 THR THR C . n 
C 3 562 SER 562 585 585 SER SER C . n 
C 3 563 ASP 563 586 586 ASP ASP C . n 
C 3 564 ASP 564 587 587 ASP ASP C . n 
C 3 565 PHE 565 588 588 PHE PHE C . n 
C 3 566 LYS 566 589 589 LYS LYS C . n 
C 3 567 PRO 567 590 590 PRO PRO C . n 
C 3 568 GLY 568 591 591 GLY GLY C . n 
C 3 569 VAL 569 592 592 VAL VAL C . n 
C 3 570 ARG 570 593 593 ARG ARG C . n 
C 3 571 TYR 571 594 594 TYR TYR C . n 
C 3 572 ASN 572 595 595 ASN ASN C . n 
C 3 573 PHE 573 596 596 PHE PHE C . n 
C 3 574 ARG 574 597 597 ARG ARG C . n 
C 3 575 ILE 575 598 598 ILE ILE C . n 
C 3 576 PHE 576 599 599 PHE PHE C . n 
C 3 577 GLU 577 600 600 GLU GLU C . n 
C 3 578 ARG 578 601 601 ARG ARG C . n 
C 3 579 SER 579 602 602 SER SER C . n 
C 3 580 VAL 580 603 603 VAL VAL C . n 
C 3 581 GLU 581 604 604 GLU GLU C . n 
C 3 582 HIS 582 605 605 HIS HIS C . n 
C 3 583 LYS 583 606 606 LYS LYS C . n 
C 3 584 ALA 584 607 607 ALA ALA C . n 
C 3 585 ARG 585 608 608 ARG ARG C . n 
C 3 586 LEU 586 609 609 LEU LEU C . n 
C 3 587 VAL 587 610 610 VAL VAL C . n 
C 3 588 GLU 588 611 611 GLU GLU C . n 
C 3 589 LYS 589 612 612 LYS LYS C . n 
C 3 590 GLN 590 613 613 GLN GLN C . n 
C 3 591 ARG 591 614 614 ARG ARG C . n 
C 3 592 GLY 592 615 615 GLY GLY C . n 
C 3 593 TYR 593 616 616 TYR TYR C . n 
C 3 594 THR 594 617 617 THR THR C . n 
C 3 595 GLN 595 618 618 GLN GLN C . n 
C 3 596 GLU 596 619 619 GLU GLU C . n 
C 3 597 LEU 597 620 620 LEU LEU C . n 
C 3 598 ALA 598 621 621 ALA ALA C . n 
C 3 599 PRO 599 622 622 PRO PRO C . n 
C 3 600 LEU 600 623 623 LEU LEU C . n 
C 3 601 VAL 601 624 624 VAL VAL C . n 
C 3 602 ASN 602 625 625 ASN ASN C . n 
C 3 603 PRO 603 626 626 PRO PRO C . n 
C 3 604 LYS 604 627 627 LYS LYS C . n 
C 3 605 VAL 605 628 628 VAL VAL C . n 
C 3 606 GLU 606 629 629 GLU GLU C . n 
C 3 607 ILE 607 630 630 ILE ILE C . n 
C 3 608 PRO 608 631 631 PRO PRO C . n 
C 3 609 TYR 609 632 632 TYR TYR C . n 
C 3 610 SER 610 633 633 SER SER C . n 
C 3 611 THR 611 634 634 THR THR C . n 
C 3 612 PRO 612 635 635 PRO PRO C . n 
C 3 613 ASN 613 636 636 ASN ASN C . n 
C 3 614 SER 614 637 637 SER SER C . n 
C 3 615 PHE 615 638 638 PHE PHE C . n 
C 3 616 VAL 616 639 639 VAL VAL C . n 
C 3 617 LEU 617 640 640 LEU LEU C . n 
C 3 618 ARG 618 641 641 ARG ARG C . n 
C 3 619 TRP 619 642 642 TRP TRP C . n 
C 3 620 PRO 620 643 643 PRO PRO C . n 
C 3 621 ASP 621 644 644 ASP ASP C . n 
C 3 622 TYR 622 645 645 TYR TYR C . n 
C 3 623 ASP 623 646 646 ASP ASP C . n 
C 3 624 SER 624 647 647 SER SER C . n 
C 3 625 ASP 625 648 648 ASP ASP C . n 
C 3 626 PHE 626 649 649 PHE PHE C . n 
C 3 627 GLN 627 650 650 GLN GLN C . n 
C 3 628 ALA 628 651 651 ALA ALA C . n 
C 3 629 GLY 629 652 652 GLY GLY C . n 
C 3 630 PHE 630 653 653 PHE PHE C . n 
C 3 631 ILE 631 654 654 ILE ILE C . n 
C 3 632 LYS 632 655 655 LYS LYS C . n 
C 3 633 GLY 633 656 656 GLY GLY C . n 
C 3 634 TYR 634 657 657 TYR TYR C . n 
C 3 635 LEU 635 658 658 LEU LEU C . n 
C 3 636 VAL 636 659 659 VAL VAL C . n 
C 3 637 TYR 637 660 660 TYR TYR C . n 
C 3 638 VAL 638 661 661 VAL VAL C . n 
C 3 639 LYS 639 662 662 LYS LYS C . n 
C 3 640 SER 640 663 663 SER SER C . n 
C 3 641 LYS 641 664 664 LYS LYS C . n 
C 3 642 GLU 642 665 665 GLU GLU C . n 
C 3 643 MET 643 666 666 MET MET C . n 
C 3 644 GLN 644 667 667 GLN GLN C . n 
C 3 645 CYS 645 668 668 CYS CYS C . n 
C 3 646 ASN 646 669 669 ASN ASN C . n 
C 3 647 GLN 647 670 670 GLN GLN C . n 
C 3 648 PRO 648 671 671 PRO PRO C . n 
C 3 649 TRP 649 672 672 TRP TRP C . n 
C 3 650 GLU 650 673 673 GLU GLU C . n 
C 3 651 ARG 651 674 674 ARG ARG C . n 
C 3 652 THR 652 675 675 THR THR C . n 
C 3 653 LEU 653 676 676 LEU LEU C . n 
C 3 654 LEU 654 677 677 LEU LEU C . n 
C 3 655 PRO 655 678 678 PRO PRO C . n 
C 3 656 ASP 656 679 679 ASP ASP C . n 
C 3 657 ASN 657 680 680 ASN ASN C . n 
C 3 658 SER 658 681 681 SER SER C . n 
C 3 659 VAL 659 682 682 VAL VAL C . n 
C 3 660 LEU 660 683 683 LEU LEU C . n 
C 3 661 CYS 661 684 684 CYS CYS C . n 
C 3 662 LYS 662 685 685 LYS LYS C . n 
C 3 663 TYR 663 686 686 TYR TYR C . n 
C 3 664 ASP 664 687 687 ASP ASP C . n 
C 3 665 ILE 665 688 688 ILE ILE C . n 
C 3 666 ASN 666 689 689 ASN ASN C . n 
C 3 667 GLY 667 690 690 GLY GLY C . n 
C 3 668 SER 668 691 691 SER SER C . n 
C 3 669 GLU 669 692 692 GLU GLU C . n 
C 3 670 THR 670 693 693 THR THR C . n 
C 3 671 LYS 671 694 694 LYS LYS C . n 
C 3 672 THR 672 695 695 THR THR C . n 
C 3 673 LEU 673 696 696 LEU LEU C . n 
C 3 674 THR 674 697 697 THR THR C . n 
C 3 675 VAL 675 698 698 VAL VAL C . n 
C 3 676 GLU 676 699 699 GLU GLU C . n 
C 3 677 ASN 677 700 700 ASN ASN C . n 
C 3 678 LEU 678 701 701 LEU LEU C . n 
C 3 679 GLN 679 702 702 GLN GLN C . n 
C 3 680 PRO 680 703 703 PRO PRO C . n 
C 3 681 GLU 681 704 704 GLU GLU C . n 
C 3 682 SER 682 705 705 SER SER C . n 
C 3 683 LEU 683 706 706 LEU LEU C . n 
C 3 684 TYR 684 707 707 TYR TYR C . n 
C 3 685 GLU 685 708 708 GLU GLU C . n 
C 3 686 PHE 686 709 709 PHE PHE C . n 
C 3 687 PHE 687 710 710 PHE PHE C . n 
C 3 688 VAL 688 711 711 VAL VAL C . n 
C 3 689 THR 689 712 712 THR THR C . n 
C 3 690 PRO 690 713 713 PRO PRO C . n 
C 3 691 TYR 691 714 714 TYR TYR C . n 
C 3 692 THR 692 715 715 THR THR C . n 
C 3 693 SER 693 716 716 SER SER C . n 
C 3 694 ALA 694 717 717 ALA ALA C . n 
C 3 695 GLY 695 718 718 GLY GLY C . n 
C 3 696 PRO 696 719 719 PRO PRO C . n 
C 3 697 GLY 697 720 720 GLY GLY C . n 
C 3 698 PRO 698 721 721 PRO PRO C . n 
C 3 699 ASN 699 722 722 ASN ASN C . n 
C 3 700 GLU 700 723 723 GLU GLU C . n 
C 3 701 THR 701 724 724 THR THR C . n 
C 3 702 PHE 702 725 725 PHE PHE C . n 
C 3 703 THR 703 726 726 THR THR C . n 
C 3 704 LYS 704 727 727 LYS LYS C . n 
C 3 705 VAL 705 728 728 VAL VAL C . n 
C 3 706 THR 706 729 729 THR THR C . n 
C 3 707 THR 707 730 730 THR THR C . n 
C 3 708 PRO 708 731 731 PRO PRO C . n 
C 3 709 ASP 709 732 ?   ?   ?   C . n 
C 3 710 ALA 710 733 ?   ?   ?   C . n 
C 3 711 ARG 711 734 ?   ?   ?   C . n 
C 3 712 SER 712 735 ?   ?   ?   C . n 
C 3 713 HIS 713 736 ?   ?   ?   C . n 
C 3 714 MET 714 737 ?   ?   ?   C . n 
C 3 715 LEU 715 738 ?   ?   ?   C . n 
# 
loop_
_pdbx_branch_scheme.asym_id 
_pdbx_branch_scheme.entity_id 
_pdbx_branch_scheme.mon_id 
_pdbx_branch_scheme.num 
_pdbx_branch_scheme.pdb_asym_id 
_pdbx_branch_scheme.pdb_mon_id 
_pdbx_branch_scheme.pdb_seq_num 
_pdbx_branch_scheme.auth_asym_id 
_pdbx_branch_scheme.auth_mon_id 
_pdbx_branch_scheme.auth_seq_num 
_pdbx_branch_scheme.hetero 
D 4 NAG 1 D NAG 1 B NAG 1009 n 
D 4 NAG 2 D NAG 2 B NAG 1010 n 
E 4 NAG 1 E NAG 1 B NAG 1016 n 
E 4 NAG 2 E NAG 2 B NAG 1017 n 
F 4 NAG 1 F NAG 1 B NAG 1020 n 
F 4 NAG 2 F NAG 2 B NAG 1021 n 
G 4 NAG 1 G NAG 1 B NAG 1022 n 
G 4 NAG 2 G NAG 2 B NAG 1023 n 
H 4 NAG 1 H NAG 1 B NAG 1025 n 
H 4 NAG 2 H NAG 2 B NAG 1026 n 
I 4 NAG 1 I NAG 1 C NAG 1009 n 
I 4 NAG 2 I NAG 2 C NAG 1010 n 
J 4 NAG 1 J NAG 1 C NAG 1013 n 
J 4 NAG 2 J NAG 2 C NAG 1014 n 
K 4 NAG 1 K NAG 1 C NAG 1016 n 
K 4 NAG 2 K NAG 2 C NAG 1017 n 
L 4 NAG 1 L NAG 1 C NAG 1018 n 
L 4 NAG 2 L NAG 2 C NAG 1019 n 
M 4 NAG 1 M NAG 1 C NAG 1020 n 
M 4 NAG 2 M NAG 2 C NAG 1021 n 
N 4 NAG 1 N NAG 1 C NAG 1023 n 
N 4 NAG 2 N NAG 2 C NAG 1024 n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
O 5 NAG 1 701 1003 NAG NAG B . 
P 5 NAG 1 702 1006 NAG NAG B . 
Q 5 NAG 1 703 1024 NAG NAG B . 
R 5 NAG 1 801 1011 NAG NAG C . 
S 5 NAG 1 802 1012 NAG NAG C . 
T 5 NAG 1 803 1015 NAG NAG C . 
U 5 NAG 1 804 1022 NAG NAG C . 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8V2B 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8V2B 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8V2B 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.entry_id                                 8V2B 
_refine.pdbx_diffrn_id                           ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             ? 
_refine.ls_d_res_high                            . 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.B_iso_mean                               ? 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_ksol                 ? 
_refine.solvent_model_param_bsol                 ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.details                                  ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.002  ? 12348 ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.393  ? 16822 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 20.047 ? 1745  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.041  ? 1959  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.003  ? 2107  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     8V2B 
_struct.title                        
'Cryo-EM structure of mouse type II OSM receptor complex: model for full extracellular assembly' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8V2B 
_struct_keywords.text            'cytokine signaling, OSM, gp130, OSMR, CYTOKINE, CYTOKINE-RECEPTOR complex' 
_struct_keywords.pdbx_keywords   CYTOKINE/RECEPTOR 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
E N N 4 ? 
F N N 4 ? 
G N N 4 ? 
H N N 4 ? 
I N N 4 ? 
J N N 4 ? 
K N N 4 ? 
L N N 4 ? 
M N N 4 ? 
N N N 4 ? 
O N N 5 ? 
P N N 5 ? 
Q N N 5 ? 
R N N 5 ? 
S N N 5 ? 
T N N 5 ? 
U N N 5 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP ONCM_MOUSE  P53347 ? 1 
;ANRGCSNSSSQLLSQLQNQANLTGNTESLLEPYIRLQNLNTPDLRAACTQHSVAFPSEDTLRQLSKPHFLSTVYTTLDRV
LYQLDALRQKFLKTPAFPKLDSARHNILGIRNNVFCMARLLNHSLEIPEPTQTDSGASRSTTTPDVFNTKIGSCGFLWGY
HRFMGSVGRVFREWDDGSTRSRR
;
24 
2 UNP IL6RB_MOUSE Q00560 ? 2 
;QLLEPCGYIYPEFPVVQRGSNFTAICVLKEACLQHYYVNASYIVWKTNHAAVPREQVTVINRTTSSVTFTDVVLPSVQLT
CNILSFGQIEQNVYGVTMLSGFPPDKPTNLTCIVNEGKNMLCQWDPGRETYLETNYTLKSEWATEKFPDCQSKHGTSCMV
SYMPTYYVNIEVWVEAENALGKVSSESINFDPVDKVKPTPPYNLSVTNSEELSSILKLSWVSSGLGGLLDLKSDIQYRTK
DASTWIQVPLEDTMSPRTSFTVQDLKPFTEYVFRIRSIKDSGKGYWSDWSEEASGTTYEDRPSRPPSFWYKTNPSHGQEY
RSVRLIWKALPLSEANGKILDYEVILTQSKSVSQTYTVTGTELTVNLTNDRYVASLAARNKVGKSAAAVLTIPSPHVTAA
YSVVNLKAFPKDNLLWVEWTPPPKPVSKYILEWCVLSENAPCVEDWQQEDATVNRTHLRGRLLESKCYQITVTPVFATGP
GGSESLKAYLKQAAPARGPTVRTKKVGKNEAVLAWDQIPVDDQNGFIRNYSISYRTSVGKEMVVHVDSSHTEYTLSSLSS
DTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIE
;
23 
3 UNP OSMR_MOUSE  O70458 ? 3 
;EVLEEPLPLTPEIHKVSFQLKLQEVNLEWTVPALTHEELNMIFQIEISRLNISNTIWVENYSTTVKREEAVRWNWTSDIP
LECVKHFIRIRALVDDTKSLPQSSWGNWSSWKEVNAKVSVEPDKSLIFPKDKVLEEGSNVTICLMYGQNVYNVSCKLQDE
PIHGEQLDSHVSLLKLNNVVFLSDTGTNINCQATKGPKRIFGTVLFVSKVLEEPKNVSCETRDFKTLDCSWEPGVDTTLT
WRKQRFQNYTLCESFSKRCEVSNYRNSYTWQITEGSQEMYNFTLTAENQLRKRSVNINFNLTHRVHPKAPQDVTLKIIGA
TKANMTWKVHSHGNNYTLLCQVKLQYGEVIHEHNVSVHMSANYLFSDLDPDTKYKAFVRCASANHFWKWSDWTQKEFSTP
ETAPSQALDVWRQVWSENGRRIVTLFWKPLLKSQANGKIISYNIVVENEAKPTESEHYCVWAPALSTNLSLDLQPYKIRI
TTNNSMGASPESLMVLSNDSGHEEVKEKTIKGIKDAFNISWEPVSGDTMGYVVDWCAHSQDQRCDLQWKNLGPNTTSTTI
TSDDFKPGVRYNFRIFERSVEHKARLVEKQRGYTQELAPLVNPKVEIPYSTPNSFVLRWPDYDSDFQAGFIKGYLVYVKS
KEMQCNQPWERTLLPDNSVLCKYDINGSETKTLTVENLQPESLYEFFVTPYTSAGPGPNETFTKVTTPDARSHML
;
24 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8V2B A 1 ? 183 ? P53347 24 ? 206 ? 24 206 
2 2 8V2B B 1 ? 595 ? Q00560 23 ? 617 ? 23 617 
3 3 8V2B C 1 ? 715 ? O70458 24 ? 738 ? 24 738 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
2 8V2B GLU B 596 ? UNP Q00560 ? ? 'expression tag' 618 1  
2 8V2B GLN B 597 ? UNP Q00560 ? ? 'expression tag' 619 2  
2 8V2B LYS B 598 ? UNP Q00560 ? ? 'expression tag' 620 3  
2 8V2B LEU B 599 ? UNP Q00560 ? ? 'expression tag' 621 4  
2 8V2B ILE B 600 ? UNP Q00560 ? ? 'expression tag' 622 5  
2 8V2B SER B 601 ? UNP Q00560 ? ? 'expression tag' 623 6  
2 8V2B GLU B 602 ? UNP Q00560 ? ? 'expression tag' 624 7  
2 8V2B GLU B 603 ? UNP Q00560 ? ? 'expression tag' 625 8  
2 8V2B ASP B 604 ? UNP Q00560 ? ? 'expression tag' 626 9  
2 8V2B LEU B 605 ? UNP Q00560 ? ? 'expression tag' 627 10 
2 8V2B GLY B 606 ? UNP Q00560 ? ? 'expression tag' 628 11 
2 8V2B GLY B 607 ? UNP Q00560 ? ? 'expression tag' 629 12 
2 8V2B GLU B 608 ? UNP Q00560 ? ? 'expression tag' 630 13 
2 8V2B GLN B 609 ? UNP Q00560 ? ? 'expression tag' 631 14 
2 8V2B LYS B 610 ? UNP Q00560 ? ? 'expression tag' 632 15 
2 8V2B LEU B 611 ? UNP Q00560 ? ? 'expression tag' 633 16 
2 8V2B ILE B 612 ? UNP Q00560 ? ? 'expression tag' 634 17 
2 8V2B SER B 613 ? UNP Q00560 ? ? 'expression tag' 635 18 
2 8V2B GLU B 614 ? UNP Q00560 ? ? 'expression tag' 636 19 
2 8V2B GLU B 615 ? UNP Q00560 ? ? 'expression tag' 637 20 
2 8V2B ASP B 616 ? UNP Q00560 ? ? 'expression tag' 638 21 
2 8V2B LEU B 617 ? UNP Q00560 ? ? 'expression tag' 639 22 
2 8V2B HIS B 618 ? UNP Q00560 ? ? 'expression tag' 640 23 
2 8V2B HIS B 619 ? UNP Q00560 ? ? 'expression tag' 641 24 
2 8V2B HIS B 620 ? UNP Q00560 ? ? 'expression tag' 642 25 
2 8V2B HIS B 621 ? UNP Q00560 ? ? 'expression tag' 643 26 
2 8V2B HIS B 622 ? UNP Q00560 ? ? 'expression tag' 644 27 
2 8V2B HIS B 623 ? UNP Q00560 ? ? 'expression tag' 645 28 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   trimeric 
_pdbx_struct_assembly.oligomeric_count     3 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R,S,T,U 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 9   ? GLY A 24  ? SER A 32  GLY A 47  1 ? 16 
HELX_P HELX_P2  AA2 LEU A 29  ? GLN A 37  ? LEU A 52  GLN A 60  1 ? 9  
HELX_P HELX_P3  AA3 THR A 41  ? HIS A 51  ? THR A 64  HIS A 74  1 ? 11 
HELX_P HELX_P4  AA4 SER A 57  ? LEU A 64  ? SER A 80  LEU A 87  1 ? 8  
HELX_P HELX_P5  AA5 SER A 65  ? LEU A 92  ? SER A 88  LEU A 115 1 ? 28 
HELX_P HELX_P6  AA6 PRO A 98  ? LEU A 121 ? PRO A 121 LEU A 144 1 ? 24 
HELX_P HELX_P7  AA7 VAL A 146 ? SER A 178 ? VAL A 169 SER A 201 1 ? 33 
HELX_P HELX_P8  AA8 LYS B 29  ? TYR B 37  ? LYS B 51  TYR B 59  1 ? 9  
HELX_P HELX_P9  AA9 ASP B 191 ? ASP B 194 ? ASP B 213 ASP B 216 5 ? 4  
HELX_P HELX_P10 AB1 SER B 223 ? LEU B 228 ? SER B 245 LEU B 250 1 ? 6  
HELX_P HELX_P11 AB2 PRO B 249 ? MET B 254 ? PRO B 271 MET B 276 5 ? 6  
HELX_P HELX_P12 AB3 PRO B 519 ? ASN B 524 ? PRO B 541 ASN B 546 1 ? 6  
HELX_P HELX_P13 AB4 LEU C 431 ? ASN C 436 ? LEU C 454 ASN C 459 1 ? 6  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1  disulf ?    ? A CYS 5   SG  ? ? ? 1_555 A CYS 116 SG ? ? A CYS 28  A CYS 139 1_555 ? ? ? ? ? ? ? 2.029 ? ?               
disulf2  disulf ?    ? A CYS 48  SG  ? ? ? 1_555 A CYS 154 SG ? ? A CYS 71  A CYS 177 1_555 ? ? ? ? ? ? ? 2.030 ? ?               
disulf3  disulf ?    ? B CYS 6   SG  ? ? ? 1_555 B CYS 32  SG ? ? B CYS 28  B CYS 54  1_555 ? ? ? ? ? ? ? 2.031 ? ?               
disulf4  disulf ?    ? B CYS 26  SG  ? ? ? 1_555 B CYS 81  SG ? ? B CYS 48  B CYS 103 1_555 ? ? ? ? ? ? ? 2.033 ? ?               
disulf5  disulf ?    ? B CYS 112 SG  ? ? ? 1_555 B CYS 122 SG ? ? B CYS 134 B CYS 144 1_555 ? ? ? ? ? ? ? 2.030 ? ?               
disulf6  disulf ?    ? B CYS 150 SG  ? ? ? 1_555 B CYS 158 SG ? ? B CYS 172 B CYS 180 1_555 ? ? ? ? ? ? ? 2.033 ? ?               
disulf7  disulf ?    ? B CYS 434 SG  ? ? ? 1_555 B CYS 442 SG ? ? B CYS 456 B CYS 464 1_555 ? ? ? ? ? ? ? 2.032 ? ?               
disulf8  disulf ?    ? C CYS 83  SG  ? ? ? 1_555 C CYS 143 SG ? ? C CYS 106 C CYS 166 1_555 ? ? ? ? ? ? ? 2.032 ? ?               
disulf9  disulf ?    ? C CYS 155 SG  ? ? ? 1_555 C CYS 191 SG ? ? C CYS 178 C CYS 214 1_555 ? ? ? ? ? ? ? 2.031 ? ?               
disulf10 disulf ?    ? C CYS 219 SG  ? ? ? 1_555 C CYS 229 SG ? ? C CYS 242 C CYS 252 1_555 ? ? ? ? ? ? ? 2.034 ? ?               
disulf11 disulf ?    ? C CYS 252 SG  ? ? ? 1_555 C CYS 259 SG ? ? C CYS 275 C CYS 282 1_555 ? ? ? ? ? ? ? 2.035 ? ?               
disulf12 disulf ?    ? C CYS 340 SG  ? ? ? 1_555 C CYS 380 SG ? ? C CYS 363 C CYS 403 1_555 ? ? ? ? ? ? ? 2.031 ? ?               
disulf13 disulf ?    ? C CYS 536 SG  ? ? ? 1_555 C CYS 544 SG ? ? C CYS 559 C CYS 567 1_555 ? ? ? ? ? ? ? 2.030 ? ?               
disulf14 disulf ?    ? C CYS 645 SG  ? ? ? 1_555 C CYS 661 SG ? ? C CYS 668 C CYS 684 1_555 ? ? ? ? ? ? ? 2.031 ? ?               
covale1  covale one  ? B ASN 21  ND2 ? ? ? 1_555 F NAG .   C1 ? ? B ASN 43  F NAG 1   1_555 ? ? ? ? ? ? ? 1.442 ? N-Glycosylation 
covale2  covale one  ? B ASN 39  ND2 ? ? ? 1_555 H NAG .   C1 ? ? B ASN 61  H NAG 1   1_555 ? ? ? ? ? ? ? 1.452 ? N-Glycosylation 
covale3  covale one  ? B ASN 61  ND2 ? ? ? 1_555 D NAG .   C1 ? ? B ASN 83  D NAG 1   1_555 ? ? ? ? ? ? ? 1.440 ? N-Glycosylation 
covale4  covale one  ? B ASN 109 ND2 ? ? ? 1_555 G NAG .   C1 ? ? B ASN 131 G NAG 1   1_555 ? ? ? ? ? ? ? 1.444 ? N-Glycosylation 
covale5  covale one  ? B ASN 135 ND2 ? ? ? 1_555 P NAG .   C1 ? ? B ASN 157 B NAG 702 1_555 ? ? ? ? ? ? ? 1.439 ? N-Glycosylation 
covale6  covale one  ? B ASN 203 ND2 ? ? ? 1_555 O NAG .   C1 ? ? B ASN 225 B NAG 701 1_555 ? ? ? ? ? ? ? 1.441 ? N-Glycosylation 
covale7  covale one  ? B ASN 366 ND2 ? ? ? 1_555 Q NAG .   C1 ? ? B ASN 388 B NAG 703 1_555 ? ? ? ? ? ? ? 1.442 ? N-Glycosylation 
covale8  covale one  ? B ASN 529 ND2 ? ? ? 1_555 E NAG .   C1 ? ? B ASN 551 E NAG 1   1_555 ? ? ? ? ? ? ? 1.442 ? N-Glycosylation 
covale9  covale one  ? C ASN 51  ND2 ? ? ? 1_555 I NAG .   C1 ? ? C ASN 74  I NAG 1   1_555 ? ? ? ? ? ? ? 1.446 ? N-Glycosylation 
covale10 covale one  ? C ASN 74  ND2 ? ? ? 1_555 R NAG .   C1 ? ? C ASN 97  C NAG 801 1_555 ? ? ? ? ? ? ? 1.440 ? N-Glycosylation 
covale11 covale one  ? C ASN 107 ND2 ? ? ? 1_555 S NAG .   C1 ? ? C ASN 130 C NAG 802 1_555 ? ? ? ? ? ? ? 1.440 ? N-Glycosylation 
covale12 covale one  ? C ASN 139 ND2 ? ? ? 1_555 J NAG .   C1 ? ? C ASN 162 J NAG 1   1_555 ? ? ? ? ? ? ? 1.440 ? N-Glycosylation 
covale13 covale one  ? C ASN 216 ND2 ? ? ? 1_555 T NAG .   C1 ? ? C ASN 239 C NAG 803 1_555 ? ? ? ? ? ? ? 1.451 ? N-Glycosylation 
covale14 covale one  ? C ASN 248 ND2 ? ? ? 1_555 K NAG .   C1 ? ? C ASN 271 K NAG 1   1_555 ? ? ? ? ? ? ? 1.442 ? N-Glycosylation 
covale15 covale one  ? C ASN 281 ND2 ? ? ? 1_555 L NAG .   C1 ? ? C ASN 304 L NAG 1   1_555 ? ? ? ? ? ? ? 1.441 ? N-Glycosylation 
covale16 covale one  ? C ASN 300 ND2 ? ? ? 1_555 M NAG .   C1 ? ? C ASN 323 M NAG 1   1_555 ? ? ? ? ? ? ? 1.439 ? N-Glycosylation 
covale17 covale one  ? C ASN 324 ND2 ? ? ? 1_555 N NAG .   C1 ? ? C ASN 347 N NAG 1   1_555 ? ? ? ? ? ? ? 1.442 ? N-Glycosylation 
covale18 covale one  ? C ASN 354 ND2 ? ? ? 1_555 U NAG .   C1 ? ? C ASN 377 C NAG 804 1_555 ? ? ? ? ? ? ? 1.441 ? N-Glycosylation 
covale19 covale both ? D NAG .   O4  ? ? ? 1_555 D NAG .   C1 ? ? D NAG 1   D NAG 2   1_555 ? ? ? ? ? ? ? 1.442 ? ?               
covale20 covale both ? E NAG .   O4  ? ? ? 1_555 E NAG .   C1 ? ? E NAG 1   E NAG 2   1_555 ? ? ? ? ? ? ? 1.444 ? ?               
covale21 covale both ? F NAG .   O4  ? ? ? 1_555 F NAG .   C1 ? ? F NAG 1   F NAG 2   1_555 ? ? ? ? ? ? ? 1.444 ? ?               
covale22 covale both ? G NAG .   O4  ? ? ? 1_555 G NAG .   C1 ? ? G NAG 1   G NAG 2   1_555 ? ? ? ? ? ? ? 1.444 ? ?               
covale23 covale both ? H NAG .   O4  ? ? ? 1_555 H NAG .   C1 ? ? H NAG 1   H NAG 2   1_555 ? ? ? ? ? ? ? 1.442 ? ?               
covale24 covale both ? I NAG .   O4  ? ? ? 1_555 I NAG .   C1 ? ? I NAG 1   I NAG 2   1_555 ? ? ? ? ? ? ? 1.441 ? ?               
covale25 covale both ? J NAG .   O4  ? ? ? 1_555 J NAG .   C1 ? ? J NAG 1   J NAG 2   1_555 ? ? ? ? ? ? ? 1.442 ? ?               
covale26 covale both ? K NAG .   O4  ? ? ? 1_555 K NAG .   C1 ? ? K NAG 1   K NAG 2   1_555 ? ? ? ? ? ? ? 1.442 ? ?               
covale27 covale both ? L NAG .   O4  ? ? ? 1_555 L NAG .   C1 ? ? L NAG 1   L NAG 2   1_555 ? ? ? ? ? ? ? 1.441 ? ?               
covale28 covale both ? M NAG .   O4  ? ? ? 1_555 M NAG .   C1 ? ? M NAG 1   M NAG 2   1_555 ? ? ? ? ? ? ? 1.441 ? ?               
covale29 covale both ? N NAG .   O4  ? ? ? 1_555 N NAG .   C1 ? ? N NAG 1   N NAG 2   1_555 ? ? ? ? ? ? ? 1.441 ? ?               
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
disulf ? ? 
covale ? ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1  NAG D .   ? ASN B 61  ? NAG D 1   ? 1_555 ASN B 83  ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
2  NAG E .   ? ASN B 529 ? NAG E 1   ? 1_555 ASN B 551 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
3  NAG F .   ? ASN B 21  ? NAG F 1   ? 1_555 ASN B 43  ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
4  NAG G .   ? ASN B 109 ? NAG G 1   ? 1_555 ASN B 131 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
5  NAG H .   ? ASN B 39  ? NAG H 1   ? 1_555 ASN B 61  ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
6  NAG I .   ? ASN C 51  ? NAG I 1   ? 1_555 ASN C 74  ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
7  NAG J .   ? ASN C 139 ? NAG J 1   ? 1_555 ASN C 162 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
8  NAG K .   ? ASN C 248 ? NAG K 1   ? 1_555 ASN C 271 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
9  NAG L .   ? ASN C 281 ? NAG L 1   ? 1_555 ASN C 304 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
10 NAG M .   ? ASN C 300 ? NAG M 1   ? 1_555 ASN C 323 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
11 NAG N .   ? ASN C 324 ? NAG N 1   ? 1_555 ASN C 347 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
12 NAG O .   ? ASN B 203 ? NAG B 701 ? 1_555 ASN B 225 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
13 NAG P .   ? ASN B 135 ? NAG B 702 ? 1_555 ASN B 157 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
14 NAG Q .   ? ASN B 366 ? NAG B 703 ? 1_555 ASN B 388 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
15 NAG R .   ? ASN C 74  ? NAG C 801 ? 1_555 ASN C 97  ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
16 NAG S .   ? ASN C 107 ? NAG C 802 ? 1_555 ASN C 130 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
17 NAG T .   ? ASN C 216 ? NAG C 803 ? 1_555 ASN C 239 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
18 NAG U .   ? ASN C 354 ? NAG C 804 ? 1_555 ASN C 377 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
19 CYS A 5   ? CYS A 116 ? CYS A 28  ? 1_555 CYS A 139 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
20 CYS A 48  ? CYS A 154 ? CYS A 71  ? 1_555 CYS A 177 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
21 CYS B 6   ? CYS B 32  ? CYS B 28  ? 1_555 CYS B 54  ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
22 CYS B 26  ? CYS B 81  ? CYS B 48  ? 1_555 CYS B 103 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
23 CYS B 112 ? CYS B 122 ? CYS B 134 ? 1_555 CYS B 144 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
24 CYS B 150 ? CYS B 158 ? CYS B 172 ? 1_555 CYS B 180 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
25 CYS B 434 ? CYS B 442 ? CYS B 456 ? 1_555 CYS B 464 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
26 CYS C 83  ? CYS C 143 ? CYS C 106 ? 1_555 CYS C 166 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
27 CYS C 155 ? CYS C 191 ? CYS C 178 ? 1_555 CYS C 214 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
28 CYS C 219 ? CYS C 229 ? CYS C 242 ? 1_555 CYS C 252 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
29 CYS C 252 ? CYS C 259 ? CYS C 275 ? 1_555 CYS C 282 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
30 CYS C 340 ? CYS C 380 ? CYS C 363 ? 1_555 CYS C 403 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
31 CYS C 536 ? CYS C 544 ? CYS C 559 ? 1_555 CYS C 567 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
32 CYS C 645 ? CYS C 661 ? CYS C 668 ? 1_555 CYS C 684 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 TYR 10  B . ? TYR 32  B PRO 11  B ? PRO 33  B 1 0.01  
2 PHE 128 C . ? PHE 151 C PRO 129 C ? PRO 152 C 1 -1.51 
3 ALA 462 C . ? ALA 485 C PRO 463 C ? PRO 486 C 1 -1.82 
4 GLN 647 C . ? GLN 670 C PRO 648 C ? PRO 671 C 1 0.62  
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 4 ? 
AA2 ? 4 ? 
AA3 ? 4 ? 
AA4 ? 4 ? 
AA5 ? 4 ? 
AA6 ? 3 ? 
AA7 ? 4 ? 
AA8 ? 3 ? 
AA9 ? 4 ? 
AB1 ? 3 ? 
AB2 ? 4 ? 
AB3 ? 3 ? 
AB4 ? 4 ? 
AB5 ? 3 ? 
AB6 ? 4 ? 
AB7 ? 3 ? 
AB8 ? 4 ? 
AB9 ? 2 ? 
AC1 ? 3 ? 
AC2 ? 2 ? 
AC3 ? 3 ? 
AC4 ? 4 ? 
AC5 ? 3 ? 
AC6 ? 4 ? 
AC7 ? 4 ? 
AC8 ? 5 ? 
AC9 ? 2 ? 
AD1 ? 2 ? 
AD2 ? 5 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA2 1 2 ? parallel      
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? parallel      
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB1 2 3 ? anti-parallel 
AB2 1 2 ? anti-parallel 
AB2 2 3 ? anti-parallel 
AB2 3 4 ? anti-parallel 
AB3 1 2 ? anti-parallel 
AB3 2 3 ? anti-parallel 
AB4 1 2 ? anti-parallel 
AB4 2 3 ? anti-parallel 
AB4 3 4 ? anti-parallel 
AB5 1 2 ? anti-parallel 
AB5 2 3 ? anti-parallel 
AB6 1 2 ? anti-parallel 
AB6 2 3 ? anti-parallel 
AB6 3 4 ? anti-parallel 
AB7 1 2 ? anti-parallel 
AB7 2 3 ? anti-parallel 
AB8 1 2 ? parallel      
AB8 2 3 ? anti-parallel 
AB8 3 4 ? anti-parallel 
AB9 1 2 ? anti-parallel 
AC1 1 2 ? anti-parallel 
AC1 2 3 ? anti-parallel 
AC2 1 2 ? anti-parallel 
AC3 1 2 ? anti-parallel 
AC3 2 3 ? anti-parallel 
AC4 1 2 ? anti-parallel 
AC4 2 3 ? anti-parallel 
AC4 3 4 ? anti-parallel 
AC5 1 2 ? anti-parallel 
AC5 2 3 ? anti-parallel 
AC6 1 2 ? anti-parallel 
AC6 2 3 ? anti-parallel 
AC6 3 4 ? anti-parallel 
AC7 1 2 ? parallel      
AC7 2 3 ? anti-parallel 
AC7 3 4 ? anti-parallel 
AC8 1 2 ? parallel      
AC8 2 3 ? anti-parallel 
AC8 3 4 ? anti-parallel 
AC8 4 5 ? anti-parallel 
AC9 1 2 ? anti-parallel 
AD1 1 2 ? anti-parallel 
AD2 1 2 ? anti-parallel 
AD2 2 3 ? anti-parallel 
AD2 3 4 ? anti-parallel 
AD2 4 5 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ILE B 9   ? TYR B 10  ? ILE B 31  TYR B 32  
AA1 2 ASN B 21  ? CYS B 26  ? ASN B 43  CYS B 48  
AA1 3 THR B 64  ? THR B 70  ? THR B 86  THR B 92  
AA1 4 VAL B 57  ? ASN B 61  ? VAL B 79  ASN B 83  
AA2 1 VAL B 15  ? VAL B 16  ? VAL B 37  VAL B 38  
AA2 2 GLU B 90  ? SER B 100 ? GLU B 112 SER B 122 
AA2 3 VAL B 77  ? LEU B 84  ? VAL B 99  LEU B 106 
AA2 4 ILE B 43  ? THR B 47  ? ILE B 65  THR B 69  
AA3 1 CYS B 158 ? MET B 159 ? CYS B 180 MET B 181 
AA3 2 MET B 120 ? ASP B 125 ? MET B 142 ASP B 147 
AA3 3 THR B 108 ? ASN B 115 ? THR B 130 ASN B 137 
AA3 4 VAL B 196 ? LYS B 197 ? VAL B 218 LYS B 219 
AA4 1 CYS B 150 ? GLN B 151 ? CYS B 172 GLN B 173 
AA4 2 ASN B 135 ? GLU B 141 ? ASN B 157 GLU B 163 
AA4 3 ILE B 170 ? GLU B 177 ? ILE B 192 GLU B 199 
AA4 4 LYS B 182 ? SER B 184 ? LYS B 204 SER B 206 
AA5 1 CYS B 150 ? GLN B 151 ? CYS B 172 GLN B 173 
AA5 2 ASN B 135 ? GLU B 141 ? ASN B 157 GLU B 163 
AA5 3 ILE B 170 ? GLU B 177 ? ILE B 192 GLU B 199 
AA5 4 ILE B 188 ? PHE B 190 ? ILE B 210 PHE B 212 
AA6 1 TYR B 202 ? THR B 207 ? TYR B 224 THR B 229 
AA6 2 LEU B 216 ? VAL B 221 ? LEU B 238 VAL B 243 
AA6 3 SER B 259 ? VAL B 262 ? SER B 281 VAL B 284 
AA7 1 ILE B 246 ? GLN B 247 ? ILE B 268 GLN B 269 
AA7 2 LEU B 231 ? ARG B 238 ? LEU B 253 ARG B 260 
AA7 3 GLU B 270 ? LYS B 279 ? GLU B 292 LYS B 301 
AA7 4 ALA B 293 ? THR B 296 ? ALA B 315 THR B 318 
AA8 1 PHE B 308 ? THR B 312 ? PHE B 330 THR B 334 
AA8 2 ARG B 321 ? TRP B 327 ? ARG B 343 TRP B 349 
AA8 3 GLU B 362 ? LEU B 367 ? GLU B 384 LEU B 389 
AA9 1 GLN B 354 ? VAL B 358 ? GLN B 376 VAL B 380 
AA9 2 ASP B 341 ? THR B 347 ? ASP B 363 THR B 369 
AA9 3 TYR B 372 ? ARG B 379 ? TYR B 394 ARG B 401 
AA9 4 ALA B 388 ? ILE B 392 ? ALA B 410 ILE B 414 
AB1 1 VAL B 404 ? LYS B 411 ? VAL B 426 LYS B 433 
AB1 2 LEU B 414 ? THR B 420 ? LEU B 436 THR B 442 
AB1 3 ARG B 455 ? HIS B 457 ? ARG B 477 HIS B 479 
AB2 1 ASP B 445 ? ASP B 450 ? ASP B 467 ASP B 472 
AB2 2 LYS B 428 ? VAL B 435 ? LYS B 450 VAL B 457 
AB2 3 TYR B 468 ? VAL B 475 ? TYR B 490 VAL B 497 
AB2 4 GLU B 484 ? ALA B 488 ? GLU B 506 ALA B 510 
AB3 1 VAL B 501 ? ARG B 502 ? VAL B 523 ARG B 524 
AB3 2 ALA B 511 ? TRP B 515 ? ALA B 533 TRP B 537 
AB3 3 TYR B 553 ? LEU B 555 ? TYR B 575 LEU B 577 
AB4 1 MET B 542 ? ASP B 547 ? MET B 564 ASP B 569 
AB4 2 ASN B 529 ? THR B 536 ? ASN B 551 THR B 558 
AB4 3 TYR B 564 ? THR B 572 ? TYR B 586 THR B 594 
AB4 4 GLY B 575 ? PHE B 584 ? GLY B 597 PHE B 606 
AB5 1 GLU C 12  ? GLN C 19  ? GLU C 35  GLN C 42  
AB5 2 GLU C 24  ? THR C 30  ? GLU C 47  THR C 53  
AB5 3 VAL C 71  ? THR C 76  ? VAL C 94  THR C 99  
AB6 1 THR C 55  ? LYS C 66  ? THR C 78  LYS C 89  
AB6 2 GLU C 38  ? ARG C 49  ? GLU C 61  ARG C 72  
AB6 3 HIS C 86  ? VAL C 94  ? HIS C 109 VAL C 117 
AB6 4 LYS C 112 ? VAL C 114 ? LYS C 135 VAL C 137 
AB7 1 SER C 125 ? PHE C 128 ? SER C 148 PHE C 151 
AB7 2 VAL C 140 ? TYR C 146 ? VAL C 163 TYR C 169 
AB7 3 VAL C 171 ? LEU C 176 ? VAL C 194 LEU C 199 
AB8 1 VAL C 133 ? GLU C 135 ? VAL C 156 GLU C 158 
AB8 2 ILE C 200 ? SER C 208 ? ILE C 223 SER C 231 
AB8 3 THR C 187 ? LYS C 195 ? THR C 210 LYS C 218 
AB8 4 TYR C 151 ? CYS C 155 ? TYR C 174 CYS C 178 
AB9 1 THR C 226 ? SER C 230 ? THR C 249 SER C 253 
AB9 2 SER C 267 ? GLN C 271 ? SER C 290 GLN C 294 
AC1 1 ASN C 248 ? LEU C 251 ? ASN C 271 LEU C 274 
AC1 2 TYR C 280 ? GLU C 287 ? TYR C 303 GLU C 310 
AC1 3 LYS C 292 ? PHE C 299 ? LYS C 315 PHE C 322 
AC2 1 GLN C 311 ? ILE C 317 ? GLN C 334 ILE C 340 
AC2 2 ALA C 323 ? LYS C 328 ? ALA C 346 LYS C 351 
AC3 1 VAL C 349 ? GLU C 352 ? VAL C 372 GLU C 375 
AC3 2 LEU C 338 ? TYR C 346 ? LEU C 361 TYR C 369 
AC3 3 VAL C 355 ? VAL C 357 ? VAL C 378 VAL C 380 
AC4 1 VAL C 349 ? GLU C 352 ? VAL C 372 GLU C 375 
AC4 2 LEU C 338 ? TYR C 346 ? LEU C 361 TYR C 369 
AC4 3 LYS C 373 ? SER C 382 ? LYS C 396 SER C 405 
AC4 4 THR C 393 ? SER C 398 ? THR C 416 SER C 421 
AC5 1 VAL C 410 ? GLU C 417 ? VAL C 433 GLU C 440 
AC5 2 ARG C 420 ? TRP C 427 ? ARG C 443 TRP C 450 
AC5 3 SER C 466 ? LEU C 471 ? SER C 489 LEU C 494 
AC6 1 SER C 455 ? TRP C 461 ? SER C 478 TRP C 484 
AC6 2 SER C 441 ? ASN C 448 ? SER C 464 ASN C 471 
AC6 3 TYR C 476 ? ASN C 483 ? TYR C 499 ASN C 506 
AC6 4 SER C 492 ? VAL C 495 ? SER C 515 VAL C 518 
AC7 1 GLU C 507 ? LYS C 511 ? GLU C 530 LYS C 534 
AC7 2 ALA C 584 ? TYR C 593 ? ALA C 607 TYR C 616 
AC7 3 ARG C 570 ? SER C 579 ? ARG C 593 SER C 602 
AC7 4 ALA C 537 ? HIS C 538 ? ALA C 560 HIS C 561 
AC8 1 GLU C 507 ? LYS C 511 ? GLU C 530 LYS C 534 
AC8 2 ALA C 584 ? TYR C 593 ? ALA C 607 TYR C 616 
AC8 3 ARG C 570 ? SER C 579 ? ARG C 593 SER C 602 
AC8 4 THR C 528 ? TRP C 535 ? THR C 551 TRP C 558 
AC8 5 GLN C 547 ? ASN C 550 ? GLN C 570 ASN C 573 
AC9 1 ILE C 519 ? SER C 520 ? ILE C 542 SER C 543 
AC9 2 SER C 557 ? THR C 558 ? SER C 580 THR C 581 
AD1 1 PHE C 615 ? ARG C 618 ? PHE C 638 ARG C 641 
AD1 2 THR C 672 ? VAL C 675 ? THR C 695 VAL C 698 
AD2 1 GLU C 650 ? LEU C 654 ? GLU C 673 LEU C 677 
AD2 2 SER C 658 ? ASN C 666 ? SER C 681 ASN C 689 
AD2 3 GLY C 633 ? SER C 640 ? GLY C 656 SER C 663 
AD2 4 SER C 682 ? TYR C 691 ? SER C 705 TYR C 714 
AD2 5 THR C 703 ? THR C 707 ? THR C 726 THR C 730 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N TYR B 10  ? N TYR B 32  O ILE B 25  ? O ILE B 47  
AA1 2 3 N PHE B 22  ? N PHE B 44  O PHE B 69  ? O PHE B 91  
AA1 3 4 O SER B 66  ? O SER B 88  N THR B 58  ? N THR B 80  
AA2 1 2 N VAL B 16  ? N VAL B 38  O LEU B 99  ? O LEU B 121 
AA2 2 3 O MET B 98  ? O MET B 120 N VAL B 77  ? N VAL B 99  
AA2 3 4 O ASN B 82  ? O ASN B 104 N VAL B 44  ? N VAL B 66  
AA3 1 2 O CYS B 158 ? O CYS B 180 N CYS B 122 ? N CYS B 144 
AA3 2 3 O LEU B 121 ? O LEU B 143 N ILE B 113 ? N ILE B 135 
AA3 3 4 N VAL B 114 ? N VAL B 136 O LYS B 197 ? O LYS B 219 
AA4 1 2 O CYS B 150 ? O CYS B 172 N LEU B 138 ? N LEU B 160 
AA4 2 3 N LYS B 139 ? N LYS B 161 O TRP B 173 ? O TRP B 195 
AA4 3 4 N ALA B 176 ? N ALA B 198 O VAL B 183 ? O VAL B 205 
AA5 1 2 O CYS B 150 ? O CYS B 172 N LEU B 138 ? N LEU B 160 
AA5 2 3 N LYS B 139 ? N LYS B 161 O TRP B 173 ? O TRP B 195 
AA5 3 4 N ILE B 170 ? N ILE B 192 O PHE B 190 ? O PHE B 212 
AA6 1 2 N SER B 205 ? N SER B 227 O SER B 219 ? O SER B 241 
AA6 2 3 N LEU B 218 ? N LEU B 240 O PHE B 260 ? O PHE B 282 
AA7 1 2 O ILE B 246 ? O ILE B 268 N TYR B 237 ? N TYR B 259 
AA7 2 3 N LYS B 232 ? N LYS B 254 O ILE B 278 ? O ILE B 300 
AA7 3 4 N TYR B 271 ? N TYR B 293 O GLY B 295 ? O GLY B 317 
AA8 1 2 N LYS B 311 ? N LYS B 333 O ARG B 324 ? O ARG B 346 
AA8 2 3 N ARG B 321 ? N ARG B 343 O LEU B 367 ? O LEU B 389 
AA9 1 2 O VAL B 358 ? O VAL B 380 N TYR B 342 ? N TYR B 364 
AA9 2 3 N ASP B 341 ? N ASP B 363 O ARG B 379 ? O ARG B 401 
AA9 3 4 N LEU B 376 ? N LEU B 398 O ALA B 388 ? O ALA B 410 
AB1 1 2 N LYS B 411 ? N LYS B 433 O LEU B 414 ? O LEU B 436 
AB1 2 3 N VAL B 417 ? N VAL B 439 O THR B 456 ? O THR B 478 
AB2 1 2 O GLU B 449 ? O GLU B 471 N TYR B 429 ? N TYR B 451 
AB2 2 3 N GLU B 432 ? N GLU B 454 O THR B 471 ? O THR B 493 
AB2 3 4 N ILE B 470 ? N ILE B 492 O LEU B 486 ? O LEU B 508 
AB3 1 2 N ARG B 502 ? N ARG B 524 O ALA B 514 ? O ALA B 536 
AB3 2 3 N ALA B 511 ? N ALA B 533 O LEU B 555 ? O LEU B 577 
AB4 1 2 O VAL B 546 ? O VAL B 568 N TYR B 530 ? N TYR B 552 
AB4 2 3 N SER B 533 ? N SER B 555 O ARG B 567 ? O ARG B 589 
AB4 3 4 N THR B 572 ? N THR B 594 O GLY B 575 ? O GLY B 597 
AB5 1 2 N GLU C 12  ? N GLU C 35  O THR C 30  ? O THR C 53  
AB5 2 3 N LEU C 27  ? N LEU C 50  O TRP C 73  ? O TRP C 96  
AB6 1 2 O TYR C 61  ? O TYR C 84  N PHE C 43  ? N PHE C 66  
AB6 2 3 N ILE C 42  ? N ILE C 65  O LEU C 93  ? O LEU C 116 
AB6 3 4 N HIS C 86  ? N HIS C 109 O VAL C 114 ? O VAL C 137 
AB7 1 2 N LEU C 126 ? N LEU C 149 O MET C 145 ? O MET C 168 
AB7 2 3 N ILE C 142 ? N ILE C 165 O LEU C 174 ? O LEU C 197 
AB8 1 2 N LEU C 134 ? N LEU C 157 O PHE C 206 ? O PHE C 229 
AB8 2 3 O LEU C 205 ? O LEU C 228 N THR C 187 ? N THR C 210 
AB8 3 4 O THR C 194 ? O THR C 217 N ASN C 152 ? N ASN C 175 
AB9 1 2 N LEU C 227 ? N LEU C 250 O TRP C 270 ? O TRP C 293 
AC1 1 2 N THR C 250 ? N THR C 273 O THR C 285 ? O THR C 308 
AC1 2 3 N ALA C 286 ? N ALA C 309 O ARG C 293 ? O ARG C 316 
AC2 1 2 N GLN C 311 ? N GLN C 334 O LYS C 328 ? O LYS C 351 
AC3 1 2 O HIS C 351 ? O HIS C 374 N LEU C 344 ? N LEU C 367 
AC3 2 3 N LEU C 338 ? N LEU C 361 O VAL C 357 ? O VAL C 380 
AC4 1 2 O HIS C 351 ? O HIS C 374 N LEU C 344 ? N LEU C 367 
AC4 2 3 N GLN C 341 ? N GLN C 364 O ARG C 379 ? O ARG C 402 
AC4 3 4 N ALA C 376 ? N ALA C 399 O LYS C 395 ? O LYS C 418 
AC5 1 2 N TRP C 411 ? N TRP C 434 O PHE C 426 ? O PHE C 449 
AC5 2 3 N VAL C 423 ? N VAL C 446 O LEU C 469 ? O LEU C 492 
AC6 1 2 O TYR C 458 ? O TYR C 481 N ILE C 444 ? N ILE C 467 
AC6 2 3 N GLU C 447 ? N GLU C 470 O LYS C 477 ? O LYS C 500 
AC6 3 4 N ILE C 478 ? N ILE C 501 O MET C 494 ? O MET C 517 
AC7 1 2 N ILE C 510 ? N ILE C 533 O ARG C 591 ? O ARG C 614 
AC7 2 3 O GLN C 590 ? O GLN C 613 N PHE C 573 ? N PHE C 596 
AC7 3 4 O ARG C 570 ? O ARG C 593 N HIS C 538 ? N HIS C 561 
AC8 1 2 N ILE C 510 ? N ILE C 533 O ARG C 591 ? O ARG C 614 
AC8 2 3 O GLN C 590 ? O GLN C 613 N PHE C 573 ? N PHE C 596 
AC8 3 4 O PHE C 576 ? O PHE C 599 N VAL C 532 ? N VAL C 555 
AC8 4 5 N TRP C 535 ? N TRP C 558 O GLN C 547 ? O GLN C 570 
AC9 1 2 N ILE C 519 ? N ILE C 542 O THR C 558 ? O THR C 581 
AD1 1 2 N LEU C 617 ? N LEU C 640 O LEU C 673 ? O LEU C 696 
AD2 1 2 N THR C 652 ? N THR C 675 O LEU C 660 ? O LEU C 683 
AD2 2 3 O ILE C 665 ? O ILE C 688 N TYR C 634 ? N TYR C 657 
AD2 3 4 N LYS C 639 ? N LYS C 662 O GLU C 685 ? O GLU C 708 
AD2 4 5 N PHE C 686 ? N PHE C 709 O THR C 703 ? O THR C 726 
# 
_pdbx_entry_details.entry_id                   8V2B 
_pdbx_entry_details.has_ligand_of_interest     N 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 PHE A 120 ? ? -160.51 74.77   
2  1 GLN B 370 ? ? -92.13  48.74   
3  1 SER B 371 ? ? 65.40   -5.52   
4  1 LEU C 73  ? ? 72.18   -8.97   
5  1 GLU C 91  ? ? 68.48   -3.12   
6  1 LEU C 123 ? ? 52.29   71.90   
7  1 MET C 302 ? ? -174.39 146.20  
8  1 ASN C 311 ? ? -126.80 -169.62 
9  1 ASP C 394 ? ? 39.84   52.74   
10 1 ILE C 463 ? ? -94.88  -60.30  
11 1 PRO C 486 ? ? -97.68  38.55   
12 1 SER C 508 ? ? -69.99  0.27    
13 1 PRO C 671 ? ? -95.77  46.77   
14 1 ASN C 700 ? ? 61.72   61.91   
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8V2B 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    8V2B 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.67 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               99588 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.5 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               'MULTIPLE SOURCES' 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'Mouse OSM in complex with gp130 and OSMR' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       '1, 2, 3' 
# 
_em_imaging.entry_id                        8V2B 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             1400 
_em_imaging.nominal_defocus_max             2600 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              8V2B 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                8V2B 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A GLU 152 ? A GLU 129 
2  1 Y 1 A PRO 153 ? A PRO 130 
3  1 Y 1 A THR 154 ? A THR 131 
4  1 Y 1 A GLN 155 ? A GLN 132 
5  1 Y 1 A THR 156 ? A THR 133 
6  1 Y 1 A ASP 157 ? A ASP 134 
7  1 Y 1 A SER 158 ? A SER 135 
8  1 Y 1 A GLY 159 ? A GLY 136 
9  1 Y 1 A ALA 160 ? A ALA 137 
10 1 Y 1 A SER 161 ? A SER 138 
11 1 Y 1 A ARG 203 ? A ARG 180 
12 1 Y 1 A SER 204 ? A SER 181 
13 1 Y 1 A ARG 205 ? A ARG 182 
14 1 Y 1 A ARG 206 ? A ARG 183 
15 1 Y 1 B GLN 23  ? B GLN 1   
16 1 Y 1 B LEU 24  ? B LEU 2   
17 1 Y 1 B LEU 25  ? B LEU 3   
18 1 Y 1 B GLU 26  ? B GLU 4   
19 1 Y 1 B LYS 610 ? B LYS 588 
20 1 Y 1 B PHE 611 ? B PHE 589 
21 1 Y 1 B ALA 612 ? B ALA 590 
22 1 Y 1 B GLN 613 ? B GLN 591 
23 1 Y 1 B GLY 614 ? B GLY 592 
24 1 Y 1 B GLU 615 ? B GLU 593 
25 1 Y 1 B ILE 616 ? B ILE 594 
26 1 Y 1 B GLU 617 ? B GLU 595 
27 1 Y 1 B GLU 618 ? B GLU 596 
28 1 Y 1 B GLN 619 ? B GLN 597 
29 1 Y 1 B LYS 620 ? B LYS 598 
30 1 Y 1 B LEU 621 ? B LEU 599 
31 1 Y 1 B ILE 622 ? B ILE 600 
32 1 Y 1 B SER 623 ? B SER 601 
33 1 Y 1 B GLU 624 ? B GLU 602 
34 1 Y 1 B GLU 625 ? B GLU 603 
35 1 Y 1 B ASP 626 ? B ASP 604 
36 1 Y 1 B LEU 627 ? B LEU 605 
37 1 Y 1 B GLY 628 ? B GLY 606 
38 1 Y 1 B GLY 629 ? B GLY 607 
39 1 Y 1 B GLU 630 ? B GLU 608 
40 1 Y 1 B GLN 631 ? B GLN 609 
41 1 Y 1 B LYS 632 ? B LYS 610 
42 1 Y 1 B LEU 633 ? B LEU 611 
43 1 Y 1 B ILE 634 ? B ILE 612 
44 1 Y 1 B SER 635 ? B SER 613 
45 1 Y 1 B GLU 636 ? B GLU 614 
46 1 Y 1 B GLU 637 ? B GLU 615 
47 1 Y 1 B ASP 638 ? B ASP 616 
48 1 Y 1 B LEU 639 ? B LEU 617 
49 1 Y 1 B HIS 640 ? B HIS 618 
50 1 Y 1 B HIS 641 ? B HIS 619 
51 1 Y 1 B HIS 642 ? B HIS 620 
52 1 Y 1 B HIS 643 ? B HIS 621 
53 1 Y 1 B HIS 644 ? B HIS 622 
54 1 Y 1 B HIS 645 ? B HIS 623 
55 1 Y 1 C GLU 24  ? C GLU 1   
56 1 Y 1 C VAL 25  ? C VAL 2   
57 1 Y 1 C LEU 26  ? C LEU 3   
58 1 Y 1 C GLU 27  ? C GLU 4   
59 1 Y 1 C GLU 28  ? C GLU 5   
60 1 Y 1 C ASP 732 ? C ASP 709 
61 1 Y 1 C ALA 733 ? C ALA 710 
62 1 Y 1 C ARG 734 ? C ARG 711 
63 1 Y 1 C SER 735 ? C SER 712 
64 1 Y 1 C HIS 736 ? C HIS 713 
65 1 Y 1 C MET 737 ? C MET 714 
66 1 Y 1 C LEU 738 ? C LEU 715 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
NAG C1   C N R 247 
NAG C2   C N R 248 
NAG C3   C N R 249 
NAG C4   C N S 250 
NAG C5   C N R 251 
NAG C6   C N N 252 
NAG C7   C N N 253 
NAG C8   C N N 254 
NAG N2   N N N 255 
NAG O1   O N N 256 
NAG O3   O N N 257 
NAG O4   O N N 258 
NAG O5   O N N 259 
NAG O6   O N N 260 
NAG O7   O N N 261 
NAG H1   H N N 262 
NAG H2   H N N 263 
NAG H3   H N N 264 
NAG H4   H N N 265 
NAG H5   H N N 266 
NAG H61  H N N 267 
NAG H62  H N N 268 
NAG H81  H N N 269 
NAG H82  H N N 270 
NAG H83  H N N 271 
NAG HN2  H N N 272 
NAG HO1  H N N 273 
NAG HO3  H N N 274 
NAG HO4  H N N 275 
NAG HO6  H N N 276 
PHE N    N N N 277 
PHE CA   C N S 278 
PHE C    C N N 279 
PHE O    O N N 280 
PHE CB   C N N 281 
PHE CG   C Y N 282 
PHE CD1  C Y N 283 
PHE CD2  C Y N 284 
PHE CE1  C Y N 285 
PHE CE2  C Y N 286 
PHE CZ   C Y N 287 
PHE OXT  O N N 288 
PHE H    H N N 289 
PHE H2   H N N 290 
PHE HA   H N N 291 
PHE HB2  H N N 292 
PHE HB3  H N N 293 
PHE HD1  H N N 294 
PHE HD2  H N N 295 
PHE HE1  H N N 296 
PHE HE2  H N N 297 
PHE HZ   H N N 298 
PHE HXT  H N N 299 
PRO N    N N N 300 
PRO CA   C N S 301 
PRO C    C N N 302 
PRO O    O N N 303 
PRO CB   C N N 304 
PRO CG   C N N 305 
PRO CD   C N N 306 
PRO OXT  O N N 307 
PRO H    H N N 308 
PRO HA   H N N 309 
PRO HB2  H N N 310 
PRO HB3  H N N 311 
PRO HG2  H N N 312 
PRO HG3  H N N 313 
PRO HD2  H N N 314 
PRO HD3  H N N 315 
PRO HXT  H N N 316 
SER N    N N N 317 
SER CA   C N S 318 
SER C    C N N 319 
SER O    O N N 320 
SER CB   C N N 321 
SER OG   O N N 322 
SER OXT  O N N 323 
SER H    H N N 324 
SER H2   H N N 325 
SER HA   H N N 326 
SER HB2  H N N 327 
SER HB3  H N N 328 
SER HG   H N N 329 
SER HXT  H N N 330 
THR N    N N N 331 
THR CA   C N S 332 
THR C    C N N 333 
THR O    O N N 334 
THR CB   C N R 335 
THR OG1  O N N 336 
THR CG2  C N N 337 
THR OXT  O N N 338 
THR H    H N N 339 
THR H2   H N N 340 
THR HA   H N N 341 
THR HB   H N N 342 
THR HG1  H N N 343 
THR HG21 H N N 344 
THR HG22 H N N 345 
THR HG23 H N N 346 
THR HXT  H N N 347 
TRP N    N N N 348 
TRP CA   C N S 349 
TRP C    C N N 350 
TRP O    O N N 351 
TRP CB   C N N 352 
TRP CG   C Y N 353 
TRP CD1  C Y N 354 
TRP CD2  C Y N 355 
TRP NE1  N Y N 356 
TRP CE2  C Y N 357 
TRP CE3  C Y N 358 
TRP CZ2  C Y N 359 
TRP CZ3  C Y N 360 
TRP CH2  C Y N 361 
TRP OXT  O N N 362 
TRP H    H N N 363 
TRP H2   H N N 364 
TRP HA   H N N 365 
TRP HB2  H N N 366 
TRP HB3  H N N 367 
TRP HD1  H N N 368 
TRP HE1  H N N 369 
TRP HE3  H N N 370 
TRP HZ2  H N N 371 
TRP HZ3  H N N 372 
TRP HH2  H N N 373 
TRP HXT  H N N 374 
TYR N    N N N 375 
TYR CA   C N S 376 
TYR C    C N N 377 
TYR O    O N N 378 
TYR CB   C N N 379 
TYR CG   C Y N 380 
TYR CD1  C Y N 381 
TYR CD2  C Y N 382 
TYR CE1  C Y N 383 
TYR CE2  C Y N 384 
TYR CZ   C Y N 385 
TYR OH   O N N 386 
TYR OXT  O N N 387 
TYR H    H N N 388 
TYR H2   H N N 389 
TYR HA   H N N 390 
TYR HB2  H N N 391 
TYR HB3  H N N 392 
TYR HD1  H N N 393 
TYR HD2  H N N 394 
TYR HE1  H N N 395 
TYR HE2  H N N 396 
TYR HH   H N N 397 
TYR HXT  H N N 398 
VAL N    N N N 399 
VAL CA   C N S 400 
VAL C    C N N 401 
VAL O    O N N 402 
VAL CB   C N N 403 
VAL CG1  C N N 404 
VAL CG2  C N N 405 
VAL OXT  O N N 406 
VAL H    H N N 407 
VAL H2   H N N 408 
VAL HA   H N N 409 
VAL HB   H N N 410 
VAL HG11 H N N 411 
VAL HG12 H N N 412 
VAL HG13 H N N 413 
VAL HG21 H N N 414 
VAL HG22 H N N 415 
VAL HG23 H N N 416 
VAL HXT  H N N 417 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
NAG C1  C2   sing N N 235 
NAG C1  O1   sing N N 236 
NAG C1  O5   sing N N 237 
NAG C1  H1   sing N N 238 
NAG C2  C3   sing N N 239 
NAG C2  N2   sing N N 240 
NAG C2  H2   sing N N 241 
NAG C3  C4   sing N N 242 
NAG C3  O3   sing N N 243 
NAG C3  H3   sing N N 244 
NAG C4  C5   sing N N 245 
NAG C4  O4   sing N N 246 
NAG C4  H4   sing N N 247 
NAG C5  C6   sing N N 248 
NAG C5  O5   sing N N 249 
NAG C5  H5   sing N N 250 
NAG C6  O6   sing N N 251 
NAG C6  H61  sing N N 252 
NAG C6  H62  sing N N 253 
NAG C7  C8   sing N N 254 
NAG C7  N2   sing N N 255 
NAG C7  O7   doub N N 256 
NAG C8  H81  sing N N 257 
NAG C8  H82  sing N N 258 
NAG C8  H83  sing N N 259 
NAG N2  HN2  sing N N 260 
NAG O1  HO1  sing N N 261 
NAG O3  HO3  sing N N 262 
NAG O4  HO4  sing N N 263 
NAG O6  HO6  sing N N 264 
PHE N   CA   sing N N 265 
PHE N   H    sing N N 266 
PHE N   H2   sing N N 267 
PHE CA  C    sing N N 268 
PHE CA  CB   sing N N 269 
PHE CA  HA   sing N N 270 
PHE C   O    doub N N 271 
PHE C   OXT  sing N N 272 
PHE CB  CG   sing N N 273 
PHE CB  HB2  sing N N 274 
PHE CB  HB3  sing N N 275 
PHE CG  CD1  doub Y N 276 
PHE CG  CD2  sing Y N 277 
PHE CD1 CE1  sing Y N 278 
PHE CD1 HD1  sing N N 279 
PHE CD2 CE2  doub Y N 280 
PHE CD2 HD2  sing N N 281 
PHE CE1 CZ   doub Y N 282 
PHE CE1 HE1  sing N N 283 
PHE CE2 CZ   sing Y N 284 
PHE CE2 HE2  sing N N 285 
PHE CZ  HZ   sing N N 286 
PHE OXT HXT  sing N N 287 
PRO N   CA   sing N N 288 
PRO N   CD   sing N N 289 
PRO N   H    sing N N 290 
PRO CA  C    sing N N 291 
PRO CA  CB   sing N N 292 
PRO CA  HA   sing N N 293 
PRO C   O    doub N N 294 
PRO C   OXT  sing N N 295 
PRO CB  CG   sing N N 296 
PRO CB  HB2  sing N N 297 
PRO CB  HB3  sing N N 298 
PRO CG  CD   sing N N 299 
PRO CG  HG2  sing N N 300 
PRO CG  HG3  sing N N 301 
PRO CD  HD2  sing N N 302 
PRO CD  HD3  sing N N 303 
PRO OXT HXT  sing N N 304 
SER N   CA   sing N N 305 
SER N   H    sing N N 306 
SER N   H2   sing N N 307 
SER CA  C    sing N N 308 
SER CA  CB   sing N N 309 
SER CA  HA   sing N N 310 
SER C   O    doub N N 311 
SER C   OXT  sing N N 312 
SER CB  OG   sing N N 313 
SER CB  HB2  sing N N 314 
SER CB  HB3  sing N N 315 
SER OG  HG   sing N N 316 
SER OXT HXT  sing N N 317 
THR N   CA   sing N N 318 
THR N   H    sing N N 319 
THR N   H2   sing N N 320 
THR CA  C    sing N N 321 
THR CA  CB   sing N N 322 
THR CA  HA   sing N N 323 
THR C   O    doub N N 324 
THR C   OXT  sing N N 325 
THR CB  OG1  sing N N 326 
THR CB  CG2  sing N N 327 
THR CB  HB   sing N N 328 
THR OG1 HG1  sing N N 329 
THR CG2 HG21 sing N N 330 
THR CG2 HG22 sing N N 331 
THR CG2 HG23 sing N N 332 
THR OXT HXT  sing N N 333 
TRP N   CA   sing N N 334 
TRP N   H    sing N N 335 
TRP N   H2   sing N N 336 
TRP CA  C    sing N N 337 
TRP CA  CB   sing N N 338 
TRP CA  HA   sing N N 339 
TRP C   O    doub N N 340 
TRP C   OXT  sing N N 341 
TRP CB  CG   sing N N 342 
TRP CB  HB2  sing N N 343 
TRP CB  HB3  sing N N 344 
TRP CG  CD1  doub Y N 345 
TRP CG  CD2  sing Y N 346 
TRP CD1 NE1  sing Y N 347 
TRP CD1 HD1  sing N N 348 
TRP CD2 CE2  doub Y N 349 
TRP CD2 CE3  sing Y N 350 
TRP NE1 CE2  sing Y N 351 
TRP NE1 HE1  sing N N 352 
TRP CE2 CZ2  sing Y N 353 
TRP CE3 CZ3  doub Y N 354 
TRP CE3 HE3  sing N N 355 
TRP CZ2 CH2  doub Y N 356 
TRP CZ2 HZ2  sing N N 357 
TRP CZ3 CH2  sing Y N 358 
TRP CZ3 HZ3  sing N N 359 
TRP CH2 HH2  sing N N 360 
TRP OXT HXT  sing N N 361 
TYR N   CA   sing N N 362 
TYR N   H    sing N N 363 
TYR N   H2   sing N N 364 
TYR CA  C    sing N N 365 
TYR CA  CB   sing N N 366 
TYR CA  HA   sing N N 367 
TYR C   O    doub N N 368 
TYR C   OXT  sing N N 369 
TYR CB  CG   sing N N 370 
TYR CB  HB2  sing N N 371 
TYR CB  HB3  sing N N 372 
TYR CG  CD1  doub Y N 373 
TYR CG  CD2  sing Y N 374 
TYR CD1 CE1  sing Y N 375 
TYR CD1 HD1  sing N N 376 
TYR CD2 CE2  doub Y N 377 
TYR CD2 HD2  sing N N 378 
TYR CE1 CZ   doub Y N 379 
TYR CE1 HE1  sing N N 380 
TYR CE2 CZ   sing Y N 381 
TYR CE2 HE2  sing N N 382 
TYR CZ  OH   sing N N 383 
TYR OH  HH   sing N N 384 
TYR OXT HXT  sing N N 385 
VAL N   CA   sing N N 386 
VAL N   H    sing N N 387 
VAL N   H2   sing N N 388 
VAL CA  C    sing N N 389 
VAL CA  CB   sing N N 390 
VAL CA  HA   sing N N 391 
VAL C   O    doub N N 392 
VAL C   OXT  sing N N 393 
VAL CB  CG1  sing N N 394 
VAL CB  CG2  sing N N 395 
VAL CB  HB   sing N N 396 
VAL CG1 HG11 sing N N 397 
VAL CG1 HG12 sing N N 398 
VAL CG1 HG13 sing N N 399 
VAL CG2 HG21 sing N N 400 
VAL CG2 HG22 sing N N 401 
VAL CG2 HG23 sing N N 402 
VAL OXT HXT  sing N N 403 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2023-11-22 
_em_admin.deposition_site    RCSB 
_em_admin.entry_id           8V2B 
_em_admin.last_update        2024-11-20 
_em_admin.map_release_date   2024-11-20 
_em_admin.title              'Cryo-EM structure of mouse type II OSM receptor complex: model for full extracellular assembly' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         40 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 BIOQUANTUM (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? ? ? 
'IMAGE ACQUISITION'        ? 2  ? ? 1 ? ? 
MASKING                    ? 3  ? ? ? ? ? 
'CTF CORRECTION'           ? 4  1 ? ? ? ? 
'LAYERLINE INDEXING'       ? 5  ? ? ? ? ? 
'DIFFRACTION INDEXING'     ? 6  ? ? ? ? ? 
'MODEL FITTING'            ? 7  ? ? ? ? ? 
'MODEL REFINEMENT'         ? 8  ? ? ? ? ? 
OTHER                      ? 9  ? ? ? ? ? 
'INITIAL EULER ASSIGNMENT' ? 10 1 ? ? ? ? 
'FINAL EULER ASSIGNMENT'   ? 11 1 ? ? ? ? 
CLASSIFICATION             ? 12 1 ? ? ? ? 
RECONSTRUCTION             ? 13 1 ? ? ? ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'Other private' 
_pdbx_audit_support.country                ? 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
loop_
_pdbx_entity_branch_list.entity_id 
_pdbx_entity_branch_list.comp_id 
_pdbx_entity_branch_list.num 
_pdbx_entity_branch_list.hetero 
4 NAG 1 n 
4 NAG 2 n 
# 
_atom_sites.entry_id                    8V2B 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1     N N   . ALA A 1 1   ? 121.228 153.405 153.386 1.00 80.43  ? 24  ALA A N   1 
ATOM   2     C CA  . ALA A 1 1   ? 120.056 152.549 153.529 1.00 80.43  ? 24  ALA A CA  1 
ATOM   3     C C   . ALA A 1 1   ? 120.016 151.495 152.429 1.00 80.43  ? 24  ALA A C   1 
ATOM   4     O O   . ALA A 1 1   ? 120.577 150.409 152.576 1.00 80.43  ? 24  ALA A O   1 
ATOM   5     C CB  . ALA A 1 1   ? 118.785 153.383 153.511 1.00 80.43  ? 24  ALA A CB  1 
ATOM   6     N N   . ASN A 1 2   ? 119.347 151.821 151.326 1.00 85.18  ? 25  ASN A N   1 
ATOM   7     C CA  . ASN A 1 2   ? 119.231 150.918 150.189 1.00 85.18  ? 25  ASN A CA  1 
ATOM   8     C C   . ASN A 1 2   ? 120.430 150.985 149.251 1.00 85.18  ? 25  ASN A C   1 
ATOM   9     O O   . ASN A 1 2   ? 120.365 150.433 148.148 1.00 85.18  ? 25  ASN A O   1 
ATOM   10    C CB  . ASN A 1 2   ? 117.947 151.217 149.410 1.00 85.18  ? 25  ASN A CB  1 
ATOM   11    C CG  . ASN A 1 2   ? 117.316 149.969 148.827 1.00 85.18  ? 25  ASN A CG  1 
ATOM   12    O OD1 . ASN A 1 2   ? 117.967 148.933 148.695 1.00 85.18  ? 25  ASN A OD1 1 
ATOM   13    N ND2 . ASN A 1 2   ? 116.039 150.062 148.472 1.00 85.18  ? 25  ASN A ND2 1 
ATOM   14    N N   . ARG A 1 3   ? 121.516 151.644 149.659 1.00 74.05  ? 26  ARG A N   1 
ATOM   15    C CA  . ARG A 1 3   ? 122.712 151.776 148.835 1.00 74.05  ? 26  ARG A CA  1 
ATOM   16    C C   . ARG A 1 3   ? 123.745 150.693 149.122 1.00 74.05  ? 26  ARG A C   1 
ATOM   17    O O   . ARG A 1 3   ? 124.948 150.924 148.946 1.00 74.05  ? 26  ARG A O   1 
ATOM   18    C CB  . ARG A 1 3   ? 123.326 153.164 149.023 1.00 74.05  ? 26  ARG A CB  1 
ATOM   19    C CG  . ARG A 1 3   ? 122.327 154.304 148.894 1.00 74.05  ? 26  ARG A CG  1 
ATOM   20    C CD  . ARG A 1 3   ? 122.934 155.492 148.165 1.00 74.05  ? 26  ARG A CD  1 
ATOM   21    N NE  . ARG A 1 3   ? 123.168 155.206 146.752 1.00 74.05  ? 26  ARG A NE  1 
ATOM   22    C CZ  . ARG A 1 3   ? 123.702 156.069 145.894 1.00 74.05  ? 26  ARG A CZ  1 
ATOM   23    N NH1 . ARG A 1 3   ? 123.878 155.723 144.626 1.00 74.05  ? 26  ARG A NH1 1 
ATOM   24    N NH2 . ARG A 1 3   ? 124.061 157.278 146.304 1.00 74.05  ? 26  ARG A NH2 1 
ATOM   25    N N   . GLY A 1 4   ? 123.307 149.520 149.561 1.00 68.33  ? 27  GLY A N   1 
ATOM   26    C CA  . GLY A 1 4   ? 124.224 148.428 149.829 1.00 68.33  ? 27  GLY A CA  1 
ATOM   27    C C   . GLY A 1 4   ? 123.461 147.218 150.315 1.00 68.33  ? 27  GLY A C   1 
ATOM   28    O O   . GLY A 1 4   ? 122.243 147.262 150.520 1.00 68.33  ? 27  GLY A O   1 
ATOM   29    N N   . CYS A 1 5   ? 124.204 146.124 150.500 1.00 74.89  ? 28  CYS A N   1 
ATOM   30    C CA  . CYS A 1 5   ? 123.663 144.866 151.016 1.00 74.89  ? 28  CYS A CA  1 
ATOM   31    C C   . CYS A 1 5   ? 122.531 144.352 150.119 1.00 74.89  ? 28  CYS A C   1 
ATOM   32    O O   . CYS A 1 5   ? 121.358 144.309 150.496 1.00 74.89  ? 28  CYS A O   1 
ATOM   33    C CB  . CYS A 1 5   ? 123.201 145.029 152.468 1.00 74.89  ? 28  CYS A CB  1 
ATOM   34    S SG  . CYS A 1 5   ? 124.556 145.140 153.656 1.00 74.89  ? 28  CYS A SG  1 
ATOM   35    N N   . SER A 1 6   ? 122.929 143.978 148.904 1.00 70.00  ? 29  SER A N   1 
ATOM   36    C CA  . SER A 1 6   ? 121.990 143.546 147.879 1.00 70.00  ? 29  SER A CA  1 
ATOM   37    C C   . SER A 1 6   ? 121.183 142.331 148.343 1.00 70.00  ? 29  SER A C   1 
ATOM   38    O O   . SER A 1 6   ? 121.479 141.691 149.355 1.00 70.00  ? 29  SER A O   1 
ATOM   39    C CB  . SER A 1 6   ? 122.731 143.221 146.583 1.00 70.00  ? 29  SER A CB  1 
ATOM   40    O OG  . SER A 1 6   ? 121.844 143.207 145.479 1.00 70.00  ? 29  SER A OG  1 
ATOM   41    N N   . ASN A 1 7   ? 120.148 142.013 147.562 1.00 62.42  ? 30  ASN A N   1 
ATOM   42    C CA  . ASN A 1 7   ? 119.173 140.989 147.921 1.00 62.42  ? 30  ASN A CA  1 
ATOM   43    C C   . ASN A 1 7   ? 119.762 139.585 147.996 1.00 62.42  ? 30  ASN A C   1 
ATOM   44    O O   . ASN A 1 7   ? 119.053 138.663 148.413 1.00 62.42  ? 30  ASN A O   1 
ATOM   45    C CB  . ASN A 1 7   ? 118.017 141.007 146.919 1.00 62.42  ? 30  ASN A CB  1 
ATOM   46    C CG  . ASN A 1 7   ? 116.737 140.434 147.495 1.00 62.42  ? 30  ASN A CG  1 
ATOM   47    O OD1 . ASN A 1 7   ? 116.435 139.255 147.315 1.00 62.42  ? 30  ASN A OD1 1 
ATOM   48    N ND2 . ASN A 1 7   ? 115.976 141.270 148.191 1.00 62.42  ? 30  ASN A ND2 1 
ATOM   49    N N   . SER A 1 8   ? 121.019 139.394 147.606 1.00 56.00  ? 31  SER A N   1 
ATOM   50    C CA  . SER A 1 8   ? 121.627 138.072 147.676 1.00 56.00  ? 31  SER A CA  1 
ATOM   51    C C   . SER A 1 8   ? 121.794 137.646 149.130 1.00 56.00  ? 31  SER A C   1 
ATOM   52    O O   . SER A 1 8   ? 122.343 138.391 149.948 1.00 56.00  ? 31  SER A O   1 
ATOM   53    C CB  . SER A 1 8   ? 122.977 138.070 146.962 1.00 56.00  ? 31  SER A CB  1 
ATOM   54    O OG  . SER A 1 8   ? 123.779 136.989 147.400 1.00 56.00  ? 31  SER A OG  1 
ATOM   55    N N   . SER A 1 9   ? 121.319 136.444 149.451 1.00 51.75  ? 32  SER A N   1 
ATOM   56    C CA  . SER A 1 9   ? 121.361 135.922 150.812 1.00 51.75  ? 32  SER A CA  1 
ATOM   57    C C   . SER A 1 9   ? 122.463 134.894 151.026 1.00 51.75  ? 32  SER A C   1 
ATOM   58    O O   . SER A 1 9   ? 123.095 134.884 152.088 1.00 51.75  ? 32  SER A O   1 
ATOM   59    C CB  . SER A 1 9   ? 120.010 135.301 151.180 1.00 51.75  ? 32  SER A CB  1 
ATOM   60    O OG  . SER A 1 9   ? 120.033 134.773 152.494 1.00 51.75  ? 32  SER A OG  1 
ATOM   61    N N   . SER A 1 10  ? 122.704 134.022 150.044 1.00 47.83  ? 33  SER A N   1 
ATOM   62    C CA  . SER A 1 10  ? 123.746 133.012 150.196 1.00 47.83  ? 33  SER A CA  1 
ATOM   63    C C   . SER A 1 10  ? 125.125 133.651 150.294 1.00 47.83  ? 33  SER A C   1 
ATOM   64    O O   . SER A 1 10  ? 125.972 133.199 151.074 1.00 47.83  ? 33  SER A O   1 
ATOM   65    C CB  . SER A 1 10  ? 123.692 132.023 149.033 1.00 47.83  ? 33  SER A CB  1 
ATOM   66    O OG  . SER A 1 10  ? 124.372 130.822 149.355 1.00 47.83  ? 33  SER A OG  1 
ATOM   67    N N   . GLN A 1 11  ? 125.369 134.705 149.511 1.00 46.98  ? 34  GLN A N   1 
ATOM   68    C CA  . GLN A 1 11  ? 126.639 135.416 149.608 1.00 46.98  ? 34  GLN A CA  1 
ATOM   69    C C   . GLN A 1 11  ? 126.810 136.046 150.983 1.00 46.98  ? 34  GLN A C   1 
ATOM   70    O O   . GLN A 1 11  ? 127.905 136.018 151.557 1.00 46.98  ? 34  GLN A O   1 
ATOM   71    C CB  . GLN A 1 11  ? 126.731 136.478 148.513 1.00 46.98  ? 34  GLN A CB  1 
ATOM   72    C CG  . GLN A 1 11  ? 127.977 137.343 148.585 1.00 46.98  ? 34  GLN A CG  1 
ATOM   73    C CD  . GLN A 1 11  ? 127.946 138.489 147.594 1.00 46.98  ? 34  GLN A CD  1 
ATOM   74    O OE1 . GLN A 1 11  ? 126.960 138.686 146.885 1.00 46.98  ? 34  GLN A OE1 1 
ATOM   75    N NE2 . GLN A 1 11  ? 129.030 139.255 147.541 1.00 46.98  ? 34  GLN A NE2 1 
ATOM   76    N N   . LEU A 1 12  ? 125.734 136.612 151.533 1.00 44.65  ? 35  LEU A N   1 
ATOM   77    C CA  . LEU A 1 12  ? 125.807 137.202 152.865 1.00 44.65  ? 35  LEU A CA  1 
ATOM   78    C C   . LEU A 1 12  ? 126.092 136.141 153.921 1.00 44.65  ? 35  LEU A C   1 
ATOM   79    O O   . LEU A 1 12  ? 126.891 136.365 154.839 1.00 44.65  ? 35  LEU A O   1 
ATOM   80    C CB  . LEU A 1 12  ? 124.507 137.941 153.179 1.00 44.65  ? 35  LEU A CB  1 
ATOM   81    C CG  . LEU A 1 12  ? 124.593 139.088 154.186 1.00 44.65  ? 35  LEU A CG  1 
ATOM   82    C CD1 . LEU A 1 12  ? 125.621 140.113 153.741 1.00 44.65  ? 35  LEU A CD1 1 
ATOM   83    C CD2 . LEU A 1 12  ? 123.231 139.737 154.366 1.00 44.65  ? 35  LEU A CD2 1 
ATOM   84    N N   . LEU A 1 13  ? 125.455 134.974 153.802 1.00 45.81  ? 36  LEU A N   1 
ATOM   85    C CA  . LEU A 1 13  ? 125.706 133.896 154.754 1.00 45.81  ? 36  LEU A CA  1 
ATOM   86    C C   . LEU A 1 13  ? 127.143 133.399 154.659 1.00 45.81  ? 36  LEU A C   1 
ATOM   87    O O   . LEU A 1 13  ? 127.787 133.133 155.683 1.00 45.81  ? 36  LEU A O   1 
ATOM   88    C CB  . LEU A 1 13  ? 124.723 132.750 154.517 1.00 45.81  ? 36  LEU A CB  1 
ATOM   89    C CG  . LEU A 1 13  ? 124.822 131.562 155.474 1.00 45.81  ? 36  LEU A CG  1 
ATOM   90    C CD1 . LEU A 1 13  ? 124.582 132.010 156.905 1.00 45.81  ? 36  LEU A CD1 1 
ATOM   91    C CD2 . LEU A 1 13  ? 123.837 130.474 155.078 1.00 45.81  ? 36  LEU A CD2 1 
ATOM   92    N N   . SER A 1 14  ? 127.666 133.272 153.437 1.00 43.11  ? 37  SER A N   1 
ATOM   93    C CA  . SER A 1 14  ? 129.050 132.843 153.267 1.00 43.11  ? 37  SER A CA  1 
ATOM   94    C C   . SER A 1 14  ? 130.018 133.868 153.843 1.00 43.11  ? 37  SER A C   1 
ATOM   95    O O   . SER A 1 14  ? 131.013 133.504 154.482 1.00 43.11  ? 37  SER A O   1 
ATOM   96    C CB  . SER A 1 14  ? 129.346 132.597 151.789 1.00 43.11  ? 37  SER A CB  1 
ATOM   97    O OG  . SER A 1 14  ? 130.736 132.682 151.529 1.00 43.11  ? 37  SER A OG  1 
ATOM   98    N N   . GLN A 1 15  ? 129.742 135.158 153.629 1.00 40.93  ? 38  GLN A N   1 
ATOM   99    C CA  . GLN A 1 15  ? 130.588 136.200 154.201 1.00 40.93  ? 38  GLN A CA  1 
ATOM   100   C C   . GLN A 1 15  ? 130.555 136.160 155.723 1.00 40.93  ? 38  GLN A C   1 
ATOM   101   O O   . GLN A 1 15  ? 131.592 136.321 156.377 1.00 40.93  ? 38  GLN A O   1 
ATOM   102   C CB  . GLN A 1 15  ? 130.148 137.572 153.693 1.00 40.93  ? 38  GLN A CB  1 
ATOM   103   C CG  . GLN A 1 15  ? 130.505 137.844 152.243 1.00 40.93  ? 38  GLN A CG  1 
ATOM   104   C CD  . GLN A 1 15  ? 129.841 139.097 151.710 1.00 40.93  ? 38  GLN A CD  1 
ATOM   105   O OE1 . GLN A 1 15  ? 128.802 139.523 152.211 1.00 40.93  ? 38  GLN A OE1 1 
ATOM   106   N NE2 . GLN A 1 15  ? 130.440 139.694 150.688 1.00 40.93  ? 38  GLN A NE2 1 
ATOM   107   N N   . LEU A 1 16  ? 129.373 135.943 156.303 1.00 42.49  ? 39  LEU A N   1 
ATOM   108   C CA  . LEU A 1 16  ? 129.269 135.851 157.756 1.00 42.49  ? 39  LEU A CA  1 
ATOM   109   C C   . LEU A 1 16  ? 130.061 134.665 158.291 1.00 42.49  ? 39  LEU A C   1 
ATOM   110   O O   . LEU A 1 16  ? 130.785 134.789 159.287 1.00 42.49  ? 39  LEU A O   1 
ATOM   111   C CB  . LEU A 1 16  ? 127.803 135.748 158.172 1.00 42.49  ? 39  LEU A CB  1 
ATOM   112   C CG  . LEU A 1 16  ? 127.075 137.070 158.416 1.00 42.49  ? 39  LEU A CG  1 
ATOM   113   C CD1 . LEU A 1 16  ? 125.588 136.832 158.625 1.00 42.49  ? 39  LEU A CD1 1 
ATOM   114   C CD2 . LEU A 1 16  ? 127.676 137.796 159.607 1.00 42.49  ? 39  LEU A CD2 1 
ATOM   115   N N   . GLN A 1 17  ? 129.939 133.505 157.640 1.00 47.93  ? 40  GLN A N   1 
ATOM   116   C CA  . GLN A 1 17  ? 130.680 132.329 158.085 1.00 47.93  ? 40  GLN A CA  1 
ATOM   117   C C   . GLN A 1 17  ? 132.184 132.548 157.975 1.00 47.93  ? 40  GLN A C   1 
ATOM   118   O O   . GLN A 1 17  ? 132.942 132.168 158.876 1.00 47.93  ? 40  GLN A O   1 
ATOM   119   C CB  . GLN A 1 17  ? 130.256 131.102 157.279 1.00 47.93  ? 40  GLN A CB  1 
ATOM   120   C CG  . GLN A 1 17  ? 128.860 130.603 157.599 1.00 47.93  ? 40  GLN A CG  1 
ATOM   121   C CD  . GLN A 1 17  ? 128.489 129.368 156.803 1.00 47.93  ? 40  GLN A CD  1 
ATOM   122   O OE1 . GLN A 1 17  ? 128.114 129.458 155.634 1.00 47.93  ? 40  GLN A OE1 1 
ATOM   123   N NE2 . GLN A 1 17  ? 128.593 128.205 157.434 1.00 47.93  ? 40  GLN A NE2 1 
ATOM   124   N N   . ASN A 1 18  ? 132.634 133.169 156.882 1.00 43.48  ? 41  ASN A N   1 
ATOM   125   C CA  . ASN A 1 18  ? 134.062 133.416 156.713 1.00 43.48  ? 41  ASN A CA  1 
ATOM   126   C C   . ASN A 1 18  ? 134.579 134.407 157.749 1.00 43.48  ? 41  ASN A C   1 
ATOM   127   O O   . ASN A 1 18  ? 135.669 134.221 158.302 1.00 43.48  ? 41  ASN A O   1 
ATOM   128   C CB  . ASN A 1 18  ? 134.346 133.917 155.298 1.00 43.48  ? 41  ASN A CB  1 
ATOM   129   C CG  . ASN A 1 18  ? 134.147 132.840 154.249 1.00 43.48  ? 41  ASN A CG  1 
ATOM   130   O OD1 . ASN A 1 18  ? 133.493 131.828 154.498 1.00 43.48  ? 41  ASN A OD1 1 
ATOM   131   N ND2 . ASN A 1 18  ? 134.712 133.054 153.067 1.00 43.48  ? 41  ASN A ND2 1 
ATOM   132   N N   . GLN A 1 19  ? 133.807 135.459 158.033 1.00 39.37  ? 42  GLN A N   1 
ATOM   133   C CA  . GLN A 1 19  ? 134.224 136.424 159.045 1.00 39.37  ? 42  GLN A CA  1 
ATOM   134   C C   . GLN A 1 19  ? 134.282 135.783 160.425 1.00 39.37  ? 42  GLN A C   1 
ATOM   135   O O   . GLN A 1 19  ? 135.198 136.060 161.208 1.00 39.37  ? 42  GLN A O   1 
ATOM   136   C CB  . GLN A 1 19  ? 133.278 137.624 159.050 1.00 39.37  ? 42  GLN A CB  1 
ATOM   137   C CG  . GLN A 1 19  ? 133.560 138.637 157.957 1.00 39.37  ? 42  GLN A CG  1 
ATOM   138   C CD  . GLN A 1 19  ? 132.626 139.827 158.015 1.00 39.37  ? 42  GLN A CD  1 
ATOM   139   O OE1 . GLN A 1 19  ? 131.425 139.678 158.240 1.00 39.37  ? 42  GLN A OE1 1 
ATOM   140   N NE2 . GLN A 1 19  ? 133.174 141.020 157.815 1.00 39.37  ? 42  GLN A NE2 1 
ATOM   141   N N   . ALA A 1 20  ? 133.317 134.916 160.740 1.00 37.80  ? 43  ALA A N   1 
ATOM   142   C CA  . ALA A 1 20  ? 133.340 134.232 162.028 1.00 37.80  ? 43  ALA A CA  1 
ATOM   143   C C   . ALA A 1 20  ? 134.541 133.301 162.137 1.00 37.80  ? 43  ALA A C   1 
ATOM   144   O O   . ALA A 1 20  ? 135.210 133.262 163.177 1.00 37.80  ? 43  ALA A O   1 
ATOM   145   C CB  . ALA A 1 20  ? 132.038 133.461 162.236 1.00 37.80  ? 43  ALA A CB  1 
ATOM   146   N N   . ASN A 1 21  ? 134.834 132.548 161.073 1.00 47.93  ? 44  ASN A N   1 
ATOM   147   C CA  . ASN A 1 21  ? 135.992 131.660 161.094 1.00 47.93  ? 44  ASN A CA  1 
ATOM   148   C C   . ASN A 1 21  ? 137.299 132.437 161.183 1.00 47.93  ? 44  ASN A C   1 
ATOM   149   O O   . ASN A 1 21  ? 138.265 131.954 161.784 1.00 47.93  ? 44  ASN A O   1 
ATOM   150   C CB  . ASN A 1 21  ? 135.994 130.766 159.853 1.00 47.93  ? 44  ASN A CB  1 
ATOM   151   C CG  . ASN A 1 21  ? 134.880 129.738 159.873 1.00 47.93  ? 44  ASN A CG  1 
ATOM   152   O OD1 . ASN A 1 21  ? 133.950 129.828 160.674 1.00 47.93  ? 44  ASN A OD1 1 
ATOM   153   N ND2 . ASN A 1 21  ? 134.969 128.753 158.987 1.00 47.93  ? 44  ASN A ND2 1 
ATOM   154   N N   . LEU A 1 22  ? 137.352 133.633 160.593 1.00 42.76  ? 45  LEU A N   1 
ATOM   155   C CA  . LEU A 1 22  ? 138.570 134.433 160.659 1.00 42.76  ? 45  LEU A CA  1 
ATOM   156   C C   . LEU A 1 22  ? 138.747 135.062 162.036 1.00 42.76  ? 45  LEU A C   1 
ATOM   157   O O   . LEU A 1 22  ? 139.870 135.148 162.545 1.00 42.76  ? 45  LEU A O   1 
ATOM   158   C CB  . LEU A 1 22  ? 138.547 135.510 159.574 1.00 42.76  ? 45  LEU A CB  1 
ATOM   159   C CG  . LEU A 1 22  ? 139.764 136.433 159.472 1.00 42.76  ? 45  LEU A CG  1 
ATOM   160   C CD1 . LEU A 1 22  ? 140.166 136.620 158.020 1.00 42.76  ? 45  LEU A CD1 1 
ATOM   161   C CD2 . LEU A 1 22  ? 139.479 137.778 160.122 1.00 42.76  ? 45  LEU A CD2 1 
ATOM   162   N N   . THR A 1 23  ? 137.652 135.508 162.654 1.00 43.18  ? 46  THR A N   1 
ATOM   163   C CA  . THR A 1 23  ? 137.751 136.176 163.946 1.00 43.18  ? 46  THR A CA  1 
ATOM   164   C C   . THR A 1 23  ? 137.975 135.183 165.081 1.00 43.18  ? 46  THR A C   1 
ATOM   165   O O   . THR A 1 23  ? 138.726 135.472 166.019 1.00 43.18  ? 46  THR A O   1 
ATOM   166   C CB  . THR A 1 23  ? 136.492 137.004 164.204 1.00 43.18  ? 46  THR A CB  1 
ATOM   167   O OG1 . THR A 1 23  ? 136.266 137.887 163.099 1.00 43.18  ? 46  THR A OG1 1 
ATOM   168   C CG2 . THR A 1 23  ? 136.647 137.825 165.469 1.00 43.18  ? 46  THR A CG2 1 
ATOM   169   N N   . GLY A 1 24  ? 137.350 134.010 165.011 1.00 48.23  ? 47  GLY A N   1 
ATOM   170   C CA  . GLY A 1 24  ? 137.503 133.023 166.061 1.00 48.23  ? 47  GLY A CA  1 
ATOM   171   C C   . GLY A 1 24  ? 138.846 132.324 166.031 1.00 48.23  ? 47  GLY A C   1 
ATOM   172   O O   . GLY A 1 24  ? 138.922 131.116 165.786 1.00 48.23  ? 47  GLY A O   1 
ATOM   173   N N   . ASN A 1 25  ? 139.915 133.075 166.284 1.00 55.45  ? 48  ASN A N   1 
ATOM   174   C CA  . ASN A 1 25  ? 141.268 132.536 166.251 1.00 55.45  ? 48  ASN A CA  1 
ATOM   175   C C   . ASN A 1 25  ? 142.101 133.245 167.306 1.00 55.45  ? 48  ASN A C   1 
ATOM   176   O O   . ASN A 1 25  ? 142.177 134.477 167.311 1.00 55.45  ? 48  ASN A O   1 
ATOM   177   C CB  . ASN A 1 25  ? 141.895 132.709 164.863 1.00 55.45  ? 48  ASN A CB  1 
ATOM   178   C CG  . ASN A 1 25  ? 143.227 132.001 164.733 1.00 55.45  ? 48  ASN A CG  1 
ATOM   179   O OD1 . ASN A 1 25  ? 143.560 131.127 165.532 1.00 55.45  ? 48  ASN A OD1 1 
ATOM   180   N ND2 . ASN A 1 25  ? 143.997 132.374 163.717 1.00 55.45  ? 48  ASN A ND2 1 
ATOM   181   N N   . THR A 1 26  ? 142.723 132.465 168.195 1.00 57.07  ? 49  THR A N   1 
ATOM   182   C CA  . THR A 1 26  ? 143.486 133.044 169.295 1.00 57.07  ? 49  THR A CA  1 
ATOM   183   C C   . THR A 1 26  ? 144.706 133.820 168.818 1.00 57.07  ? 49  THR A C   1 
ATOM   184   O O   . THR A 1 26  ? 145.195 134.689 169.549 1.00 57.07  ? 49  THR A O   1 
ATOM   185   C CB  . THR A 1 26  ? 143.923 131.950 170.270 1.00 57.07  ? 49  THR A CB  1 
ATOM   186   O OG1 . THR A 1 26  ? 144.737 130.992 169.582 1.00 57.07  ? 49  THR A OG1 1 
ATOM   187   C CG2 . THR A 1 26  ? 142.710 131.246 170.858 1.00 57.07  ? 49  THR A CG2 1 
ATOM   188   N N   . GLU A 1 27  ? 145.207 133.533 167.616 1.00 54.73  ? 50  GLU A N   1 
ATOM   189   C CA  . GLU A 1 27  ? 146.351 134.260 167.081 1.00 54.73  ? 50  GLU A CA  1 
ATOM   190   C C   . GLU A 1 27  ? 145.994 135.671 166.637 1.00 54.73  ? 50  GLU A C   1 
ATOM   191   O O   . GLU A 1 27  ? 146.898 136.445 166.302 1.00 54.73  ? 50  GLU A O   1 
ATOM   192   C CB  . GLU A 1 27  ? 146.957 133.484 165.910 1.00 54.73  ? 50  GLU A CB  1 
ATOM   193   C CG  . GLU A 1 27  ? 148.426 133.780 165.652 1.00 54.73  ? 50  GLU A CG  1 
ATOM   194   C CD  . GLU A 1 27  ? 149.328 133.251 166.747 1.00 54.73  ? 50  GLU A CD  1 
ATOM   195   O OE1 . GLU A 1 27  ? 148.955 132.251 167.396 1.00 54.73  ? 50  GLU A OE1 1 
ATOM   196   O OE2 . GLU A 1 27  ? 150.411 133.836 166.961 1.00 54.73  ? 50  GLU A OE2 1 
ATOM   197   N N   . SER A 1 28  ? 144.709 136.027 166.630 1.00 49.13  ? 51  SER A N   1 
ATOM   198   C CA  . SER A 1 28  ? 144.302 137.336 166.133 1.00 49.13  ? 51  SER A CA  1 
ATOM   199   C C   . SER A 1 28  ? 144.606 138.434 167.145 1.00 49.13  ? 51  SER A C   1 
ATOM   200   O O   . SER A 1 28  ? 145.328 139.391 166.844 1.00 49.13  ? 51  SER A O   1 
ATOM   201   C CB  . SER A 1 28  ? 142.813 137.322 165.782 1.00 49.13  ? 51  SER A CB  1 
ATOM   202   O OG  . SER A 1 28  ? 142.391 138.589 165.312 1.00 49.13  ? 51  SER A OG  1 
ATOM   203   N N   . LEU A 1 29  ? 144.061 138.316 168.355 1.00 48.26  ? 52  LEU A N   1 
ATOM   204   C CA  . LEU A 1 29  ? 144.141 139.409 169.316 1.00 48.26  ? 52  LEU A CA  1 
ATOM   205   C C   . LEU A 1 29  ? 144.672 138.956 170.672 1.00 48.26  ? 52  LEU A C   1 
ATOM   206   O O   . LEU A 1 29  ? 145.318 139.735 171.380 1.00 48.26  ? 52  LEU A O   1 
ATOM   207   C CB  . LEU A 1 29  ? 142.762 140.052 169.481 1.00 48.26  ? 52  LEU A CB  1 
ATOM   208   C CG  . LEU A 1 29  ? 142.695 141.364 170.258 1.00 48.26  ? 52  LEU A CG  1 
ATOM   209   C CD1 . LEU A 1 29  ? 143.651 142.369 169.649 1.00 48.26  ? 52  LEU A CD1 1 
ATOM   210   C CD2 . LEU A 1 29  ? 141.275 141.905 170.267 1.00 48.26  ? 52  LEU A CD2 1 
ATOM   211   N N   . LEU A 1 30  ? 144.406 137.703 171.043 1.00 42.46  ? 53  LEU A N   1 
ATOM   212   C CA  . LEU A 1 30  ? 144.767 137.239 172.380 1.00 42.46  ? 53  LEU A CA  1 
ATOM   213   C C   . LEU A 1 30  ? 146.267 136.998 172.501 1.00 42.46  ? 53  LEU A C   1 
ATOM   214   O O   . LEU A 1 30  ? 146.903 137.455 173.458 1.00 42.46  ? 53  LEU A O   1 
ATOM   215   C CB  . LEU A 1 30  ? 143.993 135.968 172.720 1.00 42.46  ? 53  LEU A CB  1 
ATOM   216   C CG  . LEU A 1 30  ? 144.347 135.331 174.065 1.00 42.46  ? 53  LEU A CG  1 
ATOM   217   C CD1 . LEU A 1 30  ? 144.157 136.328 175.196 1.00 42.46  ? 53  LEU A CD1 1 
ATOM   218   C CD2 . LEU A 1 30  ? 143.515 134.084 174.302 1.00 42.46  ? 53  LEU A CD2 1 
ATOM   219   N N   . GLU A 1 31  ? 146.845 136.271 171.550 1.00 50.29  ? 54  GLU A N   1 
ATOM   220   C CA  . GLU A 1 31  ? 148.256 135.904 171.603 1.00 50.29  ? 54  GLU A CA  1 
ATOM   221   C C   . GLU A 1 31  ? 149.178 137.119 171.508 1.00 50.29  ? 54  GLU A C   1 
ATOM   222   O O   . GLU A 1 31  ? 150.161 137.189 172.258 1.00 50.29  ? 54  GLU A O   1 
ATOM   223   C CB  . GLU A 1 31  ? 148.587 134.894 170.501 1.00 50.29  ? 54  GLU A CB  1 
ATOM   224   C CG  . GLU A 1 31  ? 148.044 133.496 170.756 1.00 50.29  ? 54  GLU A CG  1 
ATOM   225   C CD  . GLU A 1 31  ? 148.765 132.784 171.885 1.00 50.29  ? 54  GLU A CD  1 
ATOM   226   O OE1 . GLU A 1 31  ? 148.444 133.050 173.062 1.00 50.29  ? 54  GLU A OE1 1 
ATOM   227   O OE2 . GLU A 1 31  ? 149.654 131.957 171.595 1.00 50.29  ? 54  GLU A OE2 1 
ATOM   228   N N   . PRO A 1 32  ? 148.930 138.085 170.609 1.00 47.15  ? 55  PRO A N   1 
ATOM   229   C CA  . PRO A 1 32  ? 149.775 139.291 170.625 1.00 47.15  ? 55  PRO A CA  1 
ATOM   230   C C   . PRO A 1 32  ? 149.687 140.063 171.928 1.00 47.15  ? 55  PRO A C   1 
ATOM   231   O O   . PRO A 1 32  ? 150.707 140.564 172.418 1.00 47.15  ? 55  PRO A O   1 
ATOM   232   C CB  . PRO A 1 32  ? 149.242 140.108 169.439 1.00 47.15  ? 55  PRO A CB  1 
ATOM   233   C CG  . PRO A 1 32  ? 148.640 139.102 168.537 1.00 47.15  ? 55  PRO A CG  1 
ATOM   234   C CD  . PRO A 1 32  ? 148.022 138.089 169.446 1.00 47.15  ? 55  PRO A CD  1 
ATOM   235   N N   . TYR A 1 33  ? 148.492 140.166 172.512 1.00 41.87  ? 56  TYR A N   1 
ATOM   236   C CA  . TYR A 1 33  ? 148.353 140.873 173.781 1.00 41.87  ? 56  TYR A CA  1 
ATOM   237   C C   . TYR A 1 33  ? 149.071 140.138 174.905 1.00 41.87  ? 56  TYR A C   1 
ATOM   238   O O   . TYR A 1 33  ? 149.647 140.770 175.797 1.00 41.87  ? 56  TYR A O   1 
ATOM   239   C CB  . TYR A 1 33  ? 146.876 141.059 174.122 1.00 41.87  ? 56  TYR A CB  1 
ATOM   240   C CG  . TYR A 1 33  ? 146.642 141.760 175.440 1.00 41.87  ? 56  TYR A CG  1 
ATOM   241   C CD1 . TYR A 1 33  ? 146.338 141.040 176.586 1.00 41.87  ? 56  TYR A CD1 1 
ATOM   242   C CD2 . TYR A 1 33  ? 146.731 143.141 175.538 1.00 41.87  ? 56  TYR A CD2 1 
ATOM   243   C CE1 . TYR A 1 33  ? 146.127 141.675 177.792 1.00 41.87  ? 56  TYR A CE1 1 
ATOM   244   C CE2 . TYR A 1 33  ? 146.521 143.785 176.740 1.00 41.87  ? 56  TYR A CE2 1 
ATOM   245   C CZ  . TYR A 1 33  ? 146.220 143.048 177.863 1.00 41.87  ? 56  TYR A CZ  1 
ATOM   246   O OH  . TYR A 1 33  ? 146.009 143.686 179.063 1.00 41.87  ? 56  TYR A OH  1 
ATOM   247   N N   . ILE A 1 34  ? 149.044 138.804 174.883 1.00 42.18  ? 57  ILE A N   1 
ATOM   248   C CA  . ILE A 1 34  ? 149.737 138.038 175.913 1.00 42.18  ? 57  ILE A CA  1 
ATOM   249   C C   . ILE A 1 34  ? 151.246 138.181 175.760 1.00 42.18  ? 57  ILE A C   1 
ATOM   250   O O   . ILE A 1 34  ? 151.969 138.369 176.746 1.00 42.18  ? 57  ILE A O   1 
ATOM   251   C CB  . ILE A 1 34  ? 149.297 136.563 175.872 1.00 42.18  ? 57  ILE A CB  1 
ATOM   252   C CG1 . ILE A 1 34  ? 147.886 136.414 176.442 1.00 42.18  ? 57  ILE A CG1 1 
ATOM   253   C CG2 . ILE A 1 34  ? 150.273 135.689 176.641 1.00 42.18  ? 57  ILE A CG2 1 
ATOM   254   C CD1 . ILE A 1 34  ? 147.422 134.979 176.554 1.00 42.18  ? 57  ILE A CD1 1 
ATOM   255   N N   . ARG A 1 35  ? 151.746 138.109 174.525 1.00 43.97  ? 58  ARG A N   1 
ATOM   256   C CA  . ARG A 1 35  ? 153.179 138.256 174.299 1.00 43.97  ? 58  ARG A CA  1 
ATOM   257   C C   . ARG A 1 35  ? 153.659 139.683 174.526 1.00 43.97  ? 58  ARG A C   1 
ATOM   258   O O   . ARG A 1 35  ? 154.856 139.891 174.753 1.00 43.97  ? 58  ARG A O   1 
ATOM   259   C CB  . ARG A 1 35  ? 153.540 137.808 172.882 1.00 43.97  ? 58  ARG A CB  1 
ATOM   260   C CG  . ARG A 1 35  ? 153.290 136.334 172.613 1.00 43.97  ? 58  ARG A CG  1 
ATOM   261   C CD  . ARG A 1 35  ? 154.072 135.857 171.402 1.00 43.97  ? 58  ARG A CD  1 
ATOM   262   N NE  . ARG A 1 35  ? 153.888 136.738 170.253 1.00 43.97  ? 58  ARG A NE  1 
ATOM   263   C CZ  . ARG A 1 35  ? 152.970 136.552 169.310 1.00 43.97  ? 58  ARG A CZ  1 
ATOM   264   N NH1 . ARG A 1 35  ? 152.149 135.514 169.377 1.00 43.97  ? 58  ARG A NH1 1 
ATOM   265   N NH2 . ARG A 1 35  ? 152.874 137.404 168.299 1.00 43.97  ? 58  ARG A NH2 1 
ATOM   266   N N   . LEU A 1 36  ? 152.760 140.667 174.469 1.00 43.33  ? 59  LEU A N   1 
ATOM   267   C CA  . LEU A 1 36  ? 153.166 142.054 174.668 1.00 43.33  ? 59  LEU A CA  1 
ATOM   268   C C   . LEU A 1 36  ? 153.239 142.418 176.146 1.00 43.33  ? 59  LEU A C   1 
ATOM   269   O O   . LEU A 1 36  ? 154.171 143.109 176.571 1.00 43.33  ? 59  LEU A O   1 
ATOM   270   C CB  . LEU A 1 36  ? 152.201 142.989 173.937 1.00 43.33  ? 59  LEU A CB  1 
ATOM   271   C CG  . LEU A 1 36  ? 152.398 144.489 174.159 1.00 43.33  ? 59  LEU A CG  1 
ATOM   272   C CD1 . LEU A 1 36  ? 153.772 144.928 173.680 1.00 43.33  ? 59  LEU A CD1 1 
ATOM   273   C CD2 . LEU A 1 36  ? 151.305 145.281 173.459 1.00 43.33  ? 59  LEU A CD2 1 
ATOM   274   N N   . GLN A 1 37  ? 152.273 141.964 176.941 1.00 41.75  ? 60  GLN A N   1 
ATOM   275   C CA  . GLN A 1 37  ? 152.200 142.318 178.353 1.00 41.75  ? 60  GLN A CA  1 
ATOM   276   C C   . GLN A 1 37  ? 153.072 141.437 179.241 1.00 41.75  ? 60  GLN A C   1 
ATOM   277   O O   . GLN A 1 37  ? 152.933 141.503 180.467 1.00 41.75  ? 60  GLN A O   1 
ATOM   278   C CB  . GLN A 1 37  ? 150.748 142.255 178.834 1.00 41.75  ? 60  GLN A CB  1 
ATOM   279   C CG  . GLN A 1 37  ? 149.800 143.156 178.064 1.00 41.75  ? 60  GLN A CG  1 
ATOM   280   C CD  . GLN A 1 37  ? 150.022 144.625 178.358 1.00 41.75  ? 60  GLN A CD  1 
ATOM   281   O OE1 . GLN A 1 37  ? 150.637 144.984 179.361 1.00 41.75  ? 60  GLN A OE1 1 
ATOM   282   N NE2 . GLN A 1 37  ? 149.520 145.485 177.481 1.00 41.75  ? 60  GLN A NE2 1 
ATOM   283   N N   . ASN A 1 38  ? 153.953 140.623 178.655 1.00 40.83  ? 61  ASN A N   1 
ATOM   284   C CA  . ASN A 1 38  ? 154.853 139.748 179.410 1.00 40.83  ? 61  ASN A CA  1 
ATOM   285   C C   . ASN A 1 38  ? 154.068 138.794 180.310 1.00 40.83  ? 61  ASN A C   1 
ATOM   286   O O   . ASN A 1 38  ? 154.292 138.713 181.519 1.00 40.83  ? 61  ASN A O   1 
ATOM   287   C CB  . ASN A 1 38  ? 155.861 140.564 180.223 1.00 40.83  ? 61  ASN A CB  1 
ATOM   288   C CG  . ASN A 1 38  ? 156.624 141.560 179.375 1.00 40.83  ? 61  ASN A CG  1 
ATOM   289   O OD1 . ASN A 1 38  ? 156.828 141.349 178.181 1.00 40.83  ? 61  ASN A OD1 1 
ATOM   290   N ND2 . ASN A 1 38  ? 157.049 142.656 179.991 1.00 40.83  ? 61  ASN A ND2 1 
ATOM   291   N N   . LEU A 1 39  ? 153.135 138.064 179.704 1.00 48.40  ? 62  LEU A N   1 
ATOM   292   C CA  . LEU A 1 39  ? 152.281 137.116 180.408 1.00 48.40  ? 62  LEU A CA  1 
ATOM   293   C C   . LEU A 1 39  ? 152.480 135.702 179.876 1.00 48.40  ? 62  LEU A C   1 
ATOM   294   O O   . LEU A 1 39  ? 151.523 134.947 179.693 1.00 48.40  ? 62  LEU A O   1 
ATOM   295   C CB  . LEU A 1 39  ? 150.814 137.527 180.306 1.00 48.40  ? 62  LEU A CB  1 
ATOM   296   C CG  . LEU A 1 39  ? 150.421 138.860 180.945 1.00 48.40  ? 62  LEU A CG  1 
ATOM   297   C CD1 . LEU A 1 39  ? 148.985 139.216 180.598 1.00 48.40  ? 62  LEU A CD1 1 
ATOM   298   C CD2 . LEU A 1 39  ? 150.609 138.811 182.451 1.00 48.40  ? 62  LEU A CD2 1 
ATOM   299   N N   . ASN A 1 40  ? 153.731 135.325 179.621 1.00 53.27  ? 63  ASN A N   1 
ATOM   300   C CA  . ASN A 1 40  ? 154.041 134.012 179.073 1.00 53.27  ? 63  ASN A CA  1 
ATOM   301   C C   . ASN A 1 40  ? 154.267 132.951 180.142 1.00 53.27  ? 63  ASN A C   1 
ATOM   302   O O   . ASN A 1 40  ? 154.417 131.774 179.800 1.00 53.27  ? 63  ASN A O   1 
ATOM   303   C CB  . ASN A 1 40  ? 155.276 134.096 178.170 1.00 53.27  ? 63  ASN A CB  1 
ATOM   304   C CG  . ASN A 1 40  ? 155.096 133.345 176.867 1.00 53.27  ? 63  ASN A CG  1 
ATOM   305   O OD1 . ASN A 1 40  ? 154.299 132.411 176.781 1.00 53.27  ? 63  ASN A OD1 1 
ATOM   306   N ND2 . ASN A 1 40  ? 155.836 133.751 175.842 1.00 53.27  ? 63  ASN A ND2 1 
ATOM   307   N N   . THR A 1 41  ? 154.297 133.333 181.415 1.00 60.14  ? 64  THR A N   1 
ATOM   308   C CA  . THR A 1 41  ? 154.470 132.358 182.481 1.00 60.14  ? 64  THR A CA  1 
ATOM   309   C C   . THR A 1 41  ? 153.224 131.481 182.591 1.00 60.14  ? 64  THR A C   1 
ATOM   310   O O   . THR A 1 41  ? 152.100 131.986 182.501 1.00 60.14  ? 64  THR A O   1 
ATOM   311   C CB  . THR A 1 41  ? 154.736 133.068 183.810 1.00 60.14  ? 64  THR A CB  1 
ATOM   312   O OG1 . THR A 1 41  ? 155.819 133.993 183.649 1.00 60.14  ? 64  THR A OG1 1 
ATOM   313   C CG2 . THR A 1 41  ? 155.094 132.071 184.902 1.00 60.14  ? 64  THR A CG2 1 
ATOM   314   N N   . PRO A 1 42  ? 153.388 130.165 182.765 1.00 61.02  ? 65  PRO A N   1 
ATOM   315   C CA  . PRO A 1 42  ? 152.208 129.288 182.874 1.00 61.02  ? 65  PRO A CA  1 
ATOM   316   C C   . PRO A 1 42  ? 151.247 129.681 183.983 1.00 61.02  ? 65  PRO A C   1 
ATOM   317   O O   . PRO A 1 42  ? 150.031 129.518 183.819 1.00 61.02  ? 65  PRO A O   1 
ATOM   318   C CB  . PRO A 1 42  ? 152.827 127.908 183.128 1.00 61.02  ? 65  PRO A CB  1 
ATOM   319   C CG  . PRO A 1 42  ? 154.166 127.983 182.486 1.00 61.02  ? 65  PRO A CG  1 
ATOM   320   C CD  . PRO A 1 42  ? 154.641 129.395 182.680 1.00 61.02  ? 65  PRO A CD  1 
ATOM   321   N N   . ASP A 1 43  ? 151.749 130.193 185.109 1.00 58.16  ? 66  ASP A N   1 
ATOM   322   C CA  . ASP A 1 43  ? 150.853 130.654 186.166 1.00 58.16  ? 66  ASP A CA  1 
ATOM   323   C C   . ASP A 1 43  ? 150.027 131.846 185.701 1.00 58.16  ? 66  ASP A C   1 
ATOM   324   O O   . ASP A 1 43  ? 148.842 131.962 186.036 1.00 58.16  ? 66  ASP A O   1 
ATOM   325   C CB  . ASP A 1 43  ? 151.655 131.010 187.417 1.00 58.16  ? 66  ASP A CB  1 
ATOM   326   C CG  . ASP A 1 43  ? 152.369 129.813 188.009 1.00 58.16  ? 66  ASP A CG  1 
ATOM   327   O OD1 . ASP A 1 43  ? 152.221 128.700 187.461 1.00 58.16  ? 66  ASP A OD1 1 
ATOM   328   O OD2 . ASP A 1 43  ? 153.079 129.984 189.022 1.00 58.16  ? 66  ASP A OD2 1 
ATOM   329   N N   . LEU A 1 44  ? 150.632 132.737 184.914 1.00 52.30  ? 67  LEU A N   1 
ATOM   330   C CA  . LEU A 1 44  ? 149.888 133.873 184.383 1.00 52.30  ? 67  LEU A CA  1 
ATOM   331   C C   . LEU A 1 44  ? 148.822 133.418 183.393 1.00 52.30  ? 67  LEU A C   1 
ATOM   332   O O   . LEU A 1 44  ? 147.722 133.980 183.357 1.00 52.30  ? 67  LEU A O   1 
ATOM   333   C CB  . LEU A 1 44  ? 150.849 134.868 183.736 1.00 52.30  ? 67  LEU A CB  1 
ATOM   334   C CG  . LEU A 1 44  ? 151.936 135.397 184.674 1.00 52.30  ? 67  LEU A CG  1 
ATOM   335   C CD1 . LEU A 1 44  ? 152.888 136.329 183.945 1.00 52.30  ? 67  LEU A CD1 1 
ATOM   336   C CD2 . LEU A 1 44  ? 151.315 136.093 185.874 1.00 52.30  ? 67  LEU A CD2 1 
ATOM   337   N N   . ARG A 1 45  ? 149.117 132.387 182.598 1.00 58.64  ? 68  ARG A N   1 
ATOM   338   C CA  . ARG A 1 45  ? 148.108 131.856 181.686 1.00 58.64  ? 68  ARG A CA  1 
ATOM   339   C C   . ARG A 1 45  ? 146.982 131.169 182.449 1.00 58.64  ? 68  ARG A C   1 
ATOM   340   O O   . ARG A 1 45  ? 145.815 131.240 182.045 1.00 58.64  ? 68  ARG A O   1 
ATOM   341   C CB  . ARG A 1 45  ? 148.755 130.894 180.691 1.00 58.64  ? 68  ARG A CB  1 
ATOM   342   C CG  . ARG A 1 45  ? 149.738 131.562 179.747 1.00 58.64  ? 68  ARG A CG  1 
ATOM   343   C CD  . ARG A 1 45  ? 149.910 130.765 178.467 1.00 58.64  ? 68  ARG A CD  1 
ATOM   344   N NE  . ARG A 1 45  ? 150.722 131.481 177.488 1.00 58.64  ? 68  ARG A NE  1 
ATOM   345   C CZ  . ARG A 1 45  ? 150.871 131.105 176.222 1.00 58.64  ? 68  ARG A CZ  1 
ATOM   346   N NH1 . ARG A 1 45  ? 150.262 130.015 175.776 1.00 58.64  ? 68  ARG A NH1 1 
ATOM   347   N NH2 . ARG A 1 45  ? 151.629 131.819 175.402 1.00 58.64  ? 68  ARG A NH2 1 
ATOM   348   N N   . ALA A 1 46  ? 147.310 130.504 183.559 1.00 60.59  ? 69  ALA A N   1 
ATOM   349   C CA  . ALA A 1 46  ? 146.269 129.915 184.395 1.00 60.59  ? 69  ALA A CA  1 
ATOM   350   C C   . ALA A 1 46  ? 145.384 130.994 185.007 1.00 60.59  ? 69  ALA A C   1 
ATOM   351   O O   . ALA A 1 46  ? 144.159 130.839 185.076 1.00 60.59  ? 69  ALA A O   1 
ATOM   352   C CB  . ALA A 1 46  ? 146.898 129.050 185.487 1.00 60.59  ? 69  ALA A CB  1 
ATOM   353   N N   . ALA A 1 47  ? 145.989 132.096 185.455 1.00 59.35  ? 70  ALA A N   1 
ATOM   354   C CA  . ALA A 1 47  ? 145.203 133.211 185.975 1.00 59.35  ? 70  ALA A CA  1 
ATOM   355   C C   . ALA A 1 47  ? 144.340 133.831 184.882 1.00 59.35  ? 70  ALA A C   1 
ATOM   356   O O   . ALA A 1 47  ? 143.216 134.276 185.145 1.00 59.35  ? 70  ALA A O   1 
ATOM   357   C CB  . ALA A 1 47  ? 146.124 134.262 186.594 1.00 59.35  ? 70  ALA A CB  1 
ATOM   358   N N   . CYS A 1 48  ? 144.856 133.877 183.652 1.00 66.64  ? 71  CYS A N   1 
ATOM   359   C CA  . CYS A 1 48  ? 144.058 134.343 182.522 1.00 66.64  ? 71  CYS A CA  1 
ATOM   360   C C   . CYS A 1 48  ? 142.835 133.459 182.317 1.00 66.64  ? 71  CYS A C   1 
ATOM   361   O O   . CYS A 1 48  ? 141.705 133.951 182.215 1.00 66.64  ? 71  CYS A O   1 
ATOM   362   C CB  . CYS A 1 48  ? 144.913 134.366 181.254 1.00 66.64  ? 71  CYS A CB  1 
ATOM   363   S SG  . CYS A 1 48  ? 145.861 135.875 180.983 1.00 66.64  ? 71  CYS A SG  1 
ATOM   364   N N   . THR A 1 49  ? 143.047 132.144 182.252 1.00 67.09  ? 72  THR A N   1 
ATOM   365   C CA  . THR A 1 49  ? 141.948 131.217 182.005 1.00 67.09  ? 72  THR A CA  1 
ATOM   366   C C   . THR A 1 49  ? 140.975 131.135 183.174 1.00 67.09  ? 72  THR A C   1 
ATOM   367   O O   . THR A 1 49  ? 139.818 130.749 182.972 1.00 67.09  ? 72  THR A O   1 
ATOM   368   C CB  . THR A 1 49  ? 142.492 129.822 181.692 1.00 67.09  ? 72  THR A CB  1 
ATOM   369   O OG1 . THR A 1 49  ? 143.307 129.369 182.780 1.00 67.09  ? 72  THR A OG1 1 
ATOM   370   C CG2 . THR A 1 49  ? 143.323 129.849 180.418 1.00 67.09  ? 72  THR A CG2 1 
ATOM   371   N N   . GLN A 1 50  ? 141.409 131.485 184.386 1.00 76.51  ? 73  GLN A N   1 
ATOM   372   C CA  . GLN A 1 50  ? 140.519 131.414 185.541 1.00 76.51  ? 73  GLN A CA  1 
ATOM   373   C C   . GLN A 1 50  ? 139.448 132.497 185.477 1.00 76.51  ? 73  GLN A C   1 
ATOM   374   O O   . GLN A 1 50  ? 138.248 132.201 185.444 1.00 76.51  ? 73  GLN A O   1 
ATOM   375   C CB  . GLN A 1 50  ? 141.328 131.530 186.834 1.00 76.51  ? 73  GLN A CB  1 
ATOM   376   C CG  . GLN A 1 50  ? 140.480 131.536 188.095 1.00 76.51  ? 73  GLN A CG  1 
ATOM   377   C CD  . GLN A 1 50  ? 141.306 131.726 189.351 1.00 76.51  ? 73  GLN A CD  1 
ATOM   378   O OE1 . GLN A 1 50  ? 142.528 131.861 189.290 1.00 76.51  ? 73  GLN A OE1 1 
ATOM   379   N NE2 . GLN A 1 50  ? 140.641 131.736 190.500 1.00 76.51  ? 73  GLN A NE2 1 
ATOM   380   N N   . HIS A 1 51  ? 139.864 133.761 185.460 1.00 72.86  ? 74  HIS A N   1 
ATOM   381   C CA  . HIS A 1 51  ? 138.925 134.877 185.392 1.00 72.86  ? 74  HIS A CA  1 
ATOM   382   C C   . HIS A 1 51  ? 138.324 134.944 183.994 1.00 72.86  ? 74  HIS A C   1 
ATOM   383   O O   . HIS A 1 51  ? 139.024 135.252 183.024 1.00 72.86  ? 74  HIS A O   1 
ATOM   384   C CB  . HIS A 1 51  ? 139.628 136.183 185.747 1.00 72.86  ? 74  HIS A CB  1 
ATOM   385   C CG  . HIS A 1 51  ? 140.165 136.222 187.145 1.00 72.86  ? 74  HIS A CG  1 
ATOM   386   N ND1 . HIS A 1 51  ? 141.193 135.409 187.571 1.00 72.86  ? 74  HIS A ND1 1 
ATOM   387   C CD2 . HIS A 1 51  ? 139.818 136.979 188.212 1.00 72.86  ? 74  HIS A CD2 1 
ATOM   388   C CE1 . HIS A 1 51  ? 141.455 135.662 188.841 1.00 72.86  ? 74  HIS A CE1 1 
ATOM   389   N NE2 . HIS A 1 51  ? 140.634 136.611 189.254 1.00 72.86  ? 74  HIS A NE2 1 
ATOM   390   N N   . SER A 1 52  ? 137.029 134.656 183.883 1.00 68.95  ? 75  SER A N   1 
ATOM   391   C CA  . SER A 1 52  ? 136.336 134.646 182.602 1.00 68.95  ? 75  SER A CA  1 
ATOM   392   C C   . SER A 1 52  ? 135.072 135.486 182.704 1.00 68.95  ? 75  SER A C   1 
ATOM   393   O O   . SER A 1 52  ? 134.328 135.379 183.685 1.00 68.95  ? 75  SER A O   1 
ATOM   394   C CB  . SER A 1 52  ? 135.989 133.217 182.171 1.00 68.95  ? 75  SER A CB  1 
ATOM   395   O OG  . SER A 1 52  ? 135.709 133.158 180.783 1.00 68.95  ? 75  SER A OG  1 
ATOM   396   N N   . VAL A 1 53  ? 134.834 136.316 181.694 1.00 60.44  ? 76  VAL A N   1 
ATOM   397   C CA  . VAL A 1 53  ? 133.640 137.151 181.647 1.00 60.44  ? 76  VAL A CA  1 
ATOM   398   C C   . VAL A 1 53  ? 132.451 136.300 181.227 1.00 60.44  ? 76  VAL A C   1 
ATOM   399   O O   . VAL A 1 53  ? 132.562 135.439 180.345 1.00 60.44  ? 76  VAL A O   1 
ATOM   400   C CB  . VAL A 1 53  ? 133.850 138.338 180.691 1.00 60.44  ? 76  VAL A CB  1 
ATOM   401   C CG1 . VAL A 1 53  ? 132.638 139.256 180.700 1.00 60.44  ? 76  VAL A CG1 1 
ATOM   402   C CG2 . VAL A 1 53  ? 135.106 139.105 181.071 1.00 60.44  ? 76  VAL A CG2 1 
ATOM   403   N N   . ALA A 1 54  ? 131.305 136.536 181.862 1.00 55.79  ? 77  ALA A N   1 
ATOM   404   C CA  . ALA A 1 54  ? 130.099 135.764 181.584 1.00 55.79  ? 77  ALA A CA  1 
ATOM   405   C C   . ALA A 1 54  ? 129.591 136.088 180.184 1.00 55.79  ? 77  ALA A C   1 
ATOM   406   O O   . ALA A 1 54  ? 129.054 137.174 179.944 1.00 55.79  ? 77  ALA A O   1 
ATOM   407   C CB  . ALA A 1 54  ? 129.032 136.058 182.633 1.00 55.79  ? 77  ALA A CB  1 
ATOM   408   N N   . PHE A 1 55  ? 129.761 135.145 179.258 1.00 47.44  ? 78  PHE A N   1 
ATOM   409   C CA  . PHE A 1 55  ? 129.275 135.259 177.893 1.00 47.44  ? 78  PHE A CA  1 
ATOM   410   C C   . PHE A 1 55  ? 128.197 134.212 177.627 1.00 47.44  ? 78  PHE A C   1 
ATOM   411   O O   . PHE A 1 55  ? 128.158 133.174 178.295 1.00 47.44  ? 78  PHE A O   1 
ATOM   412   C CB  . PHE A 1 55  ? 130.415 135.082 176.882 1.00 47.44  ? 78  PHE A CB  1 
ATOM   413   C CG  . PHE A 1 55  ? 131.096 136.367 176.505 1.00 47.44  ? 78  PHE A CG  1 
ATOM   414   C CD1 . PHE A 1 55  ? 130.474 137.276 175.667 1.00 47.44  ? 78  PHE A CD1 1 
ATOM   415   C CD2 . PHE A 1 55  ? 132.361 136.662 176.983 1.00 47.44  ? 78  PHE A CD2 1 
ATOM   416   C CE1 . PHE A 1 55  ? 131.099 138.458 175.318 1.00 47.44  ? 78  PHE A CE1 1 
ATOM   417   C CE2 . PHE A 1 55  ? 132.991 137.842 176.637 1.00 47.44  ? 78  PHE A CE2 1 
ATOM   418   C CZ  . PHE A 1 55  ? 132.358 138.741 175.803 1.00 47.44  ? 78  PHE A CZ  1 
ATOM   419   N N   . PRO A 1 56  ? 127.299 134.457 176.673 1.00 43.83  ? 79  PRO A N   1 
ATOM   420   C CA  . PRO A 1 56  ? 126.264 133.462 176.366 1.00 43.83  ? 79  PRO A CA  1 
ATOM   421   C C   . PRO A 1 56  ? 126.878 132.152 175.893 1.00 43.83  ? 79  PRO A C   1 
ATOM   422   O O   . PRO A 1 56  ? 127.771 132.134 175.043 1.00 43.83  ? 79  PRO A O   1 
ATOM   423   C CB  . PRO A 1 56  ? 125.441 134.135 175.261 1.00 43.83  ? 79  PRO A CB  1 
ATOM   424   C CG  . PRO A 1 56  ? 125.689 135.593 175.440 1.00 43.83  ? 79  PRO A CG  1 
ATOM   425   C CD  . PRO A 1 56  ? 127.104 135.707 175.918 1.00 43.83  ? 79  PRO A CD  1 
ATOM   426   N N   . SER A 1 57  ? 126.389 131.049 176.455 1.00 55.81  ? 80  SER A N   1 
ATOM   427   C CA  . SER A 1 57  ? 126.921 129.735 176.135 1.00 55.81  ? 80  SER A CA  1 
ATOM   428   C C   . SER A 1 57  ? 126.443 129.291 174.752 1.00 55.81  ? 80  SER A C   1 
ATOM   429   O O   . SER A 1 57  ? 125.662 129.970 174.080 1.00 55.81  ? 80  SER A O   1 
ATOM   430   C CB  . SER A 1 57  ? 126.514 128.724 177.204 1.00 55.81  ? 80  SER A CB  1 
ATOM   431   O OG  . SER A 1 57  ? 125.253 128.152 176.908 1.00 55.81  ? 80  SER A OG  1 
ATOM   432   N N   . GLU A 1 58  ? 126.925 128.122 174.325 1.00 61.94  ? 81  GLU A N   1 
ATOM   433   C CA  . GLU A 1 58  ? 126.563 127.603 173.011 1.00 61.94  ? 81  GLU A CA  1 
ATOM   434   C C   . GLU A 1 58  ? 125.143 127.049 172.994 1.00 61.94  ? 81  GLU A C   1 
ATOM   435   O O   . GLU A 1 58  ? 124.412 127.240 172.015 1.00 61.94  ? 81  GLU A O   1 
ATOM   436   C CB  . GLU A 1 58  ? 127.557 126.526 172.581 1.00 61.94  ? 81  GLU A CB  1 
ATOM   437   C CG  . GLU A 1 58  ? 127.354 126.031 171.159 1.00 61.94  ? 81  GLU A CG  1 
ATOM   438   C CD  . GLU A 1 58  ? 128.309 124.915 170.789 1.00 61.94  ? 81  GLU A CD  1 
ATOM   439   O OE1 . GLU A 1 58  ? 128.510 124.002 171.618 1.00 61.94  ? 81  GLU A OE1 1 
ATOM   440   O OE2 . GLU A 1 58  ? 128.857 124.949 169.668 1.00 61.94  ? 81  GLU A OE2 1 
ATOM   441   N N   . ASP A 1 59  ? 124.737 126.363 174.064 1.00 63.80  ? 82  ASP A N   1 
ATOM   442   C CA  . ASP A 1 59  ? 123.399 125.784 174.103 1.00 63.80  ? 82  ASP A CA  1 
ATOM   443   C C   . ASP A 1 59  ? 122.328 126.867 174.129 1.00 63.80  ? 82  ASP A C   1 
ATOM   444   O O   . ASP A 1 59  ? 121.264 126.711 173.519 1.00 63.80  ? 82  ASP A O   1 
ATOM   445   C CB  . ASP A 1 59  ? 123.261 124.862 175.313 1.00 63.80  ? 82  ASP A CB  1 
ATOM   446   C CG  . ASP A 1 59  ? 121.926 124.149 175.352 1.00 63.80  ? 82  ASP A CG  1 
ATOM   447   O OD1 . ASP A 1 59  ? 121.692 123.275 174.491 1.00 63.80  ? 82  ASP A OD1 1 
ATOM   448   O OD2 . ASP A 1 59  ? 121.109 124.462 176.243 1.00 63.80  ? 82  ASP A OD2 1 
ATOM   449   N N   . THR A 1 60  ? 122.593 127.974 174.826 1.00 58.86  ? 83  THR A N   1 
ATOM   450   C CA  . THR A 1 60  ? 121.633 129.072 174.860 1.00 58.86  ? 83  THR A CA  1 
ATOM   451   C C   . THR A 1 60  ? 121.456 129.690 173.479 1.00 58.86  ? 83  THR A C   1 
ATOM   452   O O   . THR A 1 60  ? 120.336 130.028 173.079 1.00 58.86  ? 83  THR A O   1 
ATOM   453   C CB  . THR A 1 60  ? 122.079 130.130 175.869 1.00 58.86  ? 83  THR A CB  1 
ATOM   454   O OG1 . THR A 1 60  ? 122.273 129.518 177.150 1.00 58.86  ? 83  THR A OG1 1 
ATOM   455   C CG2 . THR A 1 60  ? 121.031 131.225 175.993 1.00 58.86  ? 83  THR A CG2 1 
ATOM   456   N N   . LEU A 1 61  ? 122.552 129.842 172.732 1.00 58.04  ? 84  LEU A N   1 
ATOM   457   C CA  . LEU A 1 61  ? 122.453 130.385 171.381 1.00 58.04  ? 84  LEU A CA  1 
ATOM   458   C C   . LEU A 1 61  ? 121.771 129.402 170.437 1.00 58.04  ? 84  LEU A C   1 
ATOM   459   O O   . LEU A 1 61  ? 121.034 129.811 169.533 1.00 58.04  ? 84  LEU A O   1 
ATOM   460   C CB  . LEU A 1 61  ? 123.841 130.756 170.860 1.00 58.04  ? 84  LEU A CB  1 
ATOM   461   C CG  . LEU A 1 61  ? 124.530 131.936 171.547 1.00 58.04  ? 84  LEU A CG  1 
ATOM   462   C CD1 . LEU A 1 61  ? 125.886 132.208 170.917 1.00 58.04  ? 84  LEU A CD1 1 
ATOM   463   C CD2 . LEU A 1 61  ? 123.653 133.175 171.491 1.00 58.04  ? 84  LEU A CD2 1 
ATOM   464   N N   . ARG A 1 62  ? 122.003 128.101 170.631 1.00 63.11  ? 85  ARG A N   1 
ATOM   465   C CA  . ARG A 1 62  ? 121.384 127.107 169.761 1.00 63.11  ? 85  ARG A CA  1 
ATOM   466   C C   . ARG A 1 62  ? 119.895 126.953 170.045 1.00 63.11  ? 85  ARG A C   1 
ATOM   467   O O   . ARG A 1 62  ? 119.127 126.603 169.142 1.00 63.11  ? 85  ARG A O   1 
ATOM   468   C CB  . ARG A 1 62  ? 122.090 125.761 169.912 1.00 63.11  ? 85  ARG A CB  1 
ATOM   469   C CG  . ARG A 1 62  ? 123.448 125.692 169.236 1.00 63.11  ? 85  ARG A CG  1 
ATOM   470   C CD  . ARG A 1 62  ? 124.050 124.302 169.353 1.00 63.11  ? 85  ARG A CD  1 
ATOM   471   N NE  . ARG A 1 62  ? 125.337 124.205 168.670 1.00 63.11  ? 85  ARG A NE  1 
ATOM   472   C CZ  . ARG A 1 62  ? 126.090 123.110 168.650 1.00 63.11  ? 85  ARG A CZ  1 
ATOM   473   N NH1 . ARG A 1 62  ? 125.687 122.014 169.278 1.00 63.11  ? 85  ARG A NH1 1 
ATOM   474   N NH2 . ARG A 1 62  ? 127.247 123.112 168.003 1.00 63.11  ? 85  ARG A NH2 1 
ATOM   475   N N   . GLN A 1 63  ? 119.469 127.205 171.284 1.00 65.51  ? 86  GLN A N   1 
ATOM   476   C CA  . GLN A 1 63  ? 118.065 127.031 171.634 1.00 65.51  ? 86  GLN A CA  1 
ATOM   477   C C   . GLN A 1 63  ? 117.196 128.178 171.135 1.00 65.51  ? 86  GLN A C   1 
ATOM   478   O O   . GLN A 1 63  ? 116.011 127.972 170.851 1.00 65.51  ? 86  GLN A O   1 
ATOM   479   C CB  . GLN A 1 63  ? 117.919 126.884 173.150 1.00 65.51  ? 86  GLN A CB  1 
ATOM   480   C CG  . GLN A 1 63  ? 116.559 126.380 173.600 1.00 65.51  ? 86  GLN A CG  1 
ATOM   481   C CD  . GLN A 1 63  ? 116.503 126.110 175.089 1.00 65.51  ? 86  GLN A CD  1 
ATOM   482   O OE1 . GLN A 1 63  ? 117.476 126.333 175.809 1.00 65.51  ? 86  GLN A OE1 1 
ATOM   483   N NE2 . GLN A 1 63  ? 115.360 125.625 175.561 1.00 65.51  ? 86  GLN A NE2 1 
ATOM   484   N N   . LEU A 1 64  ? 117.755 129.380 171.018 1.00 63.60  ? 87  LEU A N   1 
ATOM   485   C CA  . LEU A 1 64  ? 116.972 130.532 170.601 1.00 63.60  ? 87  LEU A CA  1 
ATOM   486   C C   . LEU A 1 64  ? 116.631 130.451 169.116 1.00 63.60  ? 87  LEU A C   1 
ATOM   487   O O   . LEU A 1 64  ? 117.262 129.727 168.340 1.00 63.60  ? 87  LEU A O   1 
ATOM   488   C CB  . LEU A 1 64  ? 117.728 131.829 170.891 1.00 63.60  ? 87  LEU A CB  1 
ATOM   489   C CG  . LEU A 1 64  ? 117.916 132.201 172.362 1.00 63.60  ? 87  LEU A CG  1 
ATOM   490   C CD1 . LEU A 1 64  ? 118.716 133.488 172.491 1.00 63.60  ? 87  LEU A CD1 1 
ATOM   491   C CD2 . LEU A 1 64  ? 116.571 132.329 173.059 1.00 63.60  ? 87  LEU A CD2 1 
ATOM   492   N N   . SER A 1 65  ? 115.611 131.212 168.725 1.00 68.92  ? 88  SER A N   1 
ATOM   493   C CA  . SER A 1 65  ? 115.208 131.297 167.330 1.00 68.92  ? 88  SER A CA  1 
ATOM   494   C C   . SER A 1 65  ? 116.169 132.204 166.563 1.00 68.92  ? 88  SER A C   1 
ATOM   495   O O   . SER A 1 65  ? 117.181 132.672 167.091 1.00 68.92  ? 88  SER A O   1 
ATOM   496   C CB  . SER A 1 65  ? 113.769 131.795 167.223 1.00 68.92  ? 88  SER A CB  1 
ATOM   497   O OG  . SER A 1 65  ? 113.247 131.564 165.926 1.00 68.92  ? 88  SER A OG  1 
ATOM   498   N N   . LYS A 1 66  ? 115.844 132.466 165.293 1.00 63.85  ? 89  LYS A N   1 
ATOM   499   C CA  . LYS A 1 66  ? 116.752 133.254 164.459 1.00 63.85  ? 89  LYS A CA  1 
ATOM   500   C C   . LYS A 1 66  ? 116.750 134.735 164.823 1.00 63.85  ? 89  LYS A C   1 
ATOM   501   O O   . LYS A 1 66  ? 117.841 135.297 165.028 1.00 63.85  ? 89  LYS A O   1 
ATOM   502   C CB  . LYS A 1 66  ? 116.426 133.027 162.980 1.00 63.85  ? 89  LYS A CB  1 
ATOM   503   C CG  . LYS A 1 66  ? 116.450 131.567 162.562 1.00 63.85  ? 89  LYS A CG  1 
ATOM   504   C CD  . LYS A 1 66  ? 116.093 131.405 161.094 1.00 63.85  ? 89  LYS A CD  1 
ATOM   505   C CE  . LYS A 1 66  ? 116.179 129.950 160.663 1.00 63.85  ? 89  LYS A CE  1 
ATOM   506   N NZ  . LYS A 1 66  ? 115.963 129.790 159.199 1.00 63.85  ? 89  LYS A NZ  1 
ATOM   507   N N   . PRO A 1 67  ? 115.605 135.428 164.914 1.00 60.94  ? 90  PRO A N   1 
ATOM   508   C CA  . PRO A 1 67  ? 115.669 136.864 165.245 1.00 60.94  ? 90  PRO A CA  1 
ATOM   509   C C   . PRO A 1 67  ? 116.224 137.138 166.632 1.00 60.94  ? 90  PRO A C   1 
ATOM   510   O O   . PRO A 1 67  ? 116.988 138.096 166.813 1.00 60.94  ? 90  PRO A O   1 
ATOM   511   C CB  . PRO A 1 67  ? 114.208 137.320 165.114 1.00 60.94  ? 90  PRO A CB  1 
ATOM   512   C CG  . PRO A 1 67  ? 113.547 136.277 164.279 1.00 60.94  ? 90  PRO A CG  1 
ATOM   513   C CD  . PRO A 1 67  ? 114.218 135.001 164.661 1.00 60.94  ? 90  PRO A CD  1 
ATOM   514   N N   . HIS A 1 68  ? 115.857 136.321 167.622 1.00 57.36  ? 91  HIS A N   1 
ATOM   515   C CA  . HIS A 1 68  ? 116.413 136.494 168.960 1.00 57.36  ? 91  HIS A CA  1 
ATOM   516   C C   . HIS A 1 68  ? 117.919 136.276 168.956 1.00 57.36  ? 91  HIS A C   1 
ATOM   517   O O   . HIS A 1 68  ? 118.662 137.001 169.630 1.00 57.36  ? 91  HIS A O   1 
ATOM   518   C CB  . HIS A 1 68  ? 115.733 135.538 169.939 1.00 57.36  ? 91  HIS A CB  1 
ATOM   519   C CG  . HIS A 1 68  ? 114.237 135.602 169.908 1.00 57.36  ? 91  HIS A CG  1 
ATOM   520   N ND1 . HIS A 1 68  ? 113.487 135.015 168.912 1.00 57.36  ? 91  HIS A ND1 1 
ATOM   521   C CD2 . HIS A 1 68  ? 113.352 136.182 170.753 1.00 57.36  ? 91  HIS A CD2 1 
ATOM   522   C CE1 . HIS A 1 68  ? 112.205 135.231 169.144 1.00 57.36  ? 91  HIS A CE1 1 
ATOM   523   N NE2 . HIS A 1 68  ? 112.096 135.938 170.254 1.00 57.36  ? 91  HIS A NE2 1 
ATOM   524   N N   . PHE A 1 69  ? 118.389 135.285 168.195 1.00 51.54  ? 92  PHE A N   1 
ATOM   525   C CA  . PHE A 1 69  ? 119.824 135.044 168.093 1.00 51.54  ? 92  PHE A CA  1 
ATOM   526   C C   . PHE A 1 69  ? 120.536 136.229 167.454 1.00 51.54  ? 92  PHE A C   1 
ATOM   527   O O   . PHE A 1 69  ? 121.607 136.643 167.916 1.00 51.54  ? 92  PHE A O   1 
ATOM   528   C CB  . PHE A 1 69  ? 120.080 133.763 167.300 1.00 51.54  ? 92  PHE A CB  1 
ATOM   529   C CG  . PHE A 1 69  ? 121.501 133.594 166.856 1.00 51.54  ? 92  PHE A CG  1 
ATOM   530   C CD1 . PHE A 1 69  ? 121.843 133.735 165.524 1.00 51.54  ? 92  PHE A CD1 1 
ATOM   531   C CD2 . PHE A 1 69  ? 122.495 133.291 167.770 1.00 51.54  ? 92  PHE A CD2 1 
ATOM   532   C CE1 . PHE A 1 69  ? 123.148 133.579 165.111 1.00 51.54  ? 92  PHE A CE1 1 
ATOM   533   C CE2 . PHE A 1 69  ? 123.804 133.134 167.362 1.00 51.54  ? 92  PHE A CE2 1 
ATOM   534   C CZ  . PHE A 1 69  ? 124.131 133.279 166.031 1.00 51.54  ? 92  PHE A CZ  1 
ATOM   535   N N   . LEU A 1 70  ? 119.952 136.794 166.394 1.00 47.24  ? 93  LEU A N   1 
ATOM   536   C CA  . LEU A 1 70  ? 120.556 137.961 165.757 1.00 47.24  ? 93  LEU A CA  1 
ATOM   537   C C   . LEU A 1 70  ? 120.605 139.148 166.712 1.00 47.24  ? 93  LEU A C   1 
ATOM   538   O O   . LEU A 1 70  ? 121.609 139.869 166.769 1.00 47.24  ? 93  LEU A O   1 
ATOM   539   C CB  . LEU A 1 70  ? 119.787 138.324 164.487 1.00 47.24  ? 93  LEU A CB  1 
ATOM   540   C CG  . LEU A 1 70  ? 119.795 137.285 163.365 1.00 47.24  ? 93  LEU A CG  1 
ATOM   541   C CD1 . LEU A 1 70  ? 119.032 137.796 162.154 1.00 47.24  ? 93  LEU A CD1 1 
ATOM   542   C CD2 . LEU A 1 70  ? 121.218 136.912 162.988 1.00 47.24  ? 93  LEU A CD2 1 
ATOM   543   N N   . SER A 1 71  ? 119.534 139.360 167.480 1.00 49.03  ? 94  SER A N   1 
ATOM   544   C CA  . SER A 1 71  ? 119.516 140.467 168.431 1.00 49.03  ? 94  SER A CA  1 
ATOM   545   C C   . SER A 1 71  ? 120.558 140.273 169.528 1.00 49.03  ? 94  SER A C   1 
ATOM   546   O O   . SER A 1 71  ? 121.234 141.231 169.930 1.00 49.03  ? 94  SER A O   1 
ATOM   547   C CB  . SER A 1 71  ? 118.121 140.616 169.035 1.00 49.03  ? 94  SER A CB  1 
ATOM   548   O OG  . SER A 1 71  ? 117.152 140.840 168.026 1.00 49.03  ? 94  SER A OG  1 
ATOM   549   N N   . THR A 1 72  ? 120.702 139.041 170.025 1.00 50.37  ? 95  THR A N   1 
ATOM   550   C CA  . THR A 1 72  ? 121.708 138.775 171.048 1.00 50.37  ? 95  THR A CA  1 
ATOM   551   C C   . THR A 1 72  ? 123.113 138.988 170.503 1.00 50.37  ? 95  THR A C   1 
ATOM   552   O O   . THR A 1 72  ? 123.978 139.538 171.196 1.00 50.37  ? 95  THR A O   1 
ATOM   553   C CB  . THR A 1 72  ? 121.556 137.354 171.588 1.00 50.37  ? 95  THR A CB  1 
ATOM   554   O OG1 . THR A 1 72  ? 121.498 136.429 170.495 1.00 50.37  ? 95  THR A OG1 1 
ATOM   555   C CG2 . THR A 1 72  ? 120.290 137.232 172.421 1.00 50.37  ? 95  THR A CG2 1 
ATOM   556   N N   . VAL A 1 73  ? 123.360 138.560 169.262 1.00 47.58  ? 96  VAL A N   1 
ATOM   557   C CA  . VAL A 1 73  ? 124.666 138.789 168.649 1.00 47.58  ? 96  VAL A CA  1 
ATOM   558   C C   . VAL A 1 73  ? 124.933 140.283 168.511 1.00 47.58  ? 96  VAL A C   1 
ATOM   559   O O   . VAL A 1 73  ? 126.043 140.758 168.780 1.00 47.58  ? 96  VAL A O   1 
ATOM   560   C CB  . VAL A 1 73  ? 124.753 138.067 167.291 1.00 47.58  ? 96  VAL A CB  1 
ATOM   561   C CG1 . VAL A 1 73  ? 125.952 138.559 166.499 1.00 47.58  ? 96  VAL A CG1 1 
ATOM   562   C CG2 . VAL A 1 73  ? 124.835 136.566 167.500 1.00 47.58  ? 96  VAL A CG2 1 
ATOM   563   N N   . TYR A 1 74  ? 123.916 141.047 168.106 1.00 46.98  ? 97  TYR A N   1 
ATOM   564   C CA  . TYR A 1 74  ? 124.068 142.494 167.979 1.00 46.98  ? 97  TYR A CA  1 
ATOM   565   C C   . TYR A 1 74  ? 124.437 143.128 169.315 1.00 46.98  ? 97  TYR A C   1 
ATOM   566   O O   . TYR A 1 74  ? 125.383 143.924 169.403 1.00 46.98  ? 97  TYR A O   1 
ATOM   567   C CB  . TYR A 1 74  ? 122.773 143.098 167.433 1.00 46.98  ? 97  TYR A CB  1 
ATOM   568   C CG  . TYR A 1 74  ? 122.955 144.369 166.637 1.00 46.98  ? 97  TYR A CG  1 
ATOM   569   C CD1 . TYR A 1 74  ? 122.712 145.610 167.209 1.00 46.98  ? 97  TYR A CD1 1 
ATOM   570   C CD2 . TYR A 1 74  ? 123.355 144.328 165.309 1.00 46.98  ? 97  TYR A CD2 1 
ATOM   571   C CE1 . TYR A 1 74  ? 122.870 146.774 166.484 1.00 46.98  ? 97  TYR A CE1 1 
ATOM   572   C CE2 . TYR A 1 74  ? 123.516 145.487 164.576 1.00 46.98  ? 97  TYR A CE2 1 
ATOM   573   C CZ  . TYR A 1 74  ? 123.273 146.707 165.168 1.00 46.98  ? 97  TYR A CZ  1 
ATOM   574   O OH  . TYR A 1 74  ? 123.432 147.864 164.442 1.00 46.98  ? 97  TYR A OH  1 
ATOM   575   N N   . THR A 1 75  ? 123.701 142.779 170.373 1.00 57.64  ? 98  THR A N   1 
ATOM   576   C CA  . THR A 1 75  ? 123.961 143.370 171.683 1.00 57.64  ? 98  THR A CA  1 
ATOM   577   C C   . THR A 1 75  ? 125.339 142.978 172.208 1.00 57.64  ? 98  THR A C   1 
ATOM   578   O O   . THR A 1 75  ? 126.060 143.812 172.774 1.00 57.64  ? 98  THR A O   1 
ATOM   579   C CB  . THR A 1 75  ? 122.872 142.953 172.671 1.00 57.64  ? 98  THR A CB  1 
ATOM   580   O OG1 . THR A 1 75  ? 121.584 143.241 172.114 1.00 57.64  ? 98  THR A OG1 1 
ATOM   581   C CG2 . THR A 1 75  ? 123.028 143.705 173.984 1.00 57.64  ? 98  THR A CG2 1 
ATOM   582   N N   . THR A 1 76  ? 125.725 141.712 172.027 1.00 48.60  ? 99  THR A N   1 
ATOM   583   C CA  . THR A 1 76  ? 127.032 141.269 172.498 1.00 48.60  ? 99  THR A CA  1 
ATOM   584   C C   . THR A 1 76  ? 128.156 141.962 171.738 1.00 48.60  ? 99  THR A C   1 
ATOM   585   O O   . THR A 1 76  ? 129.174 142.336 172.333 1.00 48.60  ? 99  THR A O   1 
ATOM   586   C CB  . THR A 1 76  ? 127.150 139.752 172.369 1.00 48.60  ? 99  THR A CB  1 
ATOM   587   O OG1 . THR A 1 76  ? 126.001 139.133 172.958 1.00 48.60  ? 99  THR A OG1 1 
ATOM   588   C CG2 . THR A 1 76  ? 128.398 139.258 173.078 1.00 48.60  ? 99  THR A CG2 1 
ATOM   589   N N   . LEU A 1 77  ? 127.989 142.153 170.427 1.00 71.03  ? 100 LEU A N   1 
ATOM   590   C CA  . LEU A 1 77  ? 129.000 142.869 169.659 1.00 71.03  ? 100 LEU A CA  1 
ATOM   591   C C   . LEU A 1 77  ? 129.093 144.325 170.096 1.00 71.03  ? 100 LEU A C   1 
ATOM   592   O O   . LEU A 1 77  ? 130.189 144.895 170.142 1.00 71.03  ? 100 LEU A O   1 
ATOM   593   C CB  . LEU A 1 77  ? 128.695 142.770 168.166 1.00 71.03  ? 100 LEU A CB  1 
ATOM   594   C CG  . LEU A 1 77  ? 128.991 141.413 167.527 1.00 71.03  ? 100 LEU A CG  1 
ATOM   595   C CD1 . LEU A 1 77  ? 128.646 141.431 166.048 1.00 71.03  ? 100 LEU A CD1 1 
ATOM   596   C CD2 . LEU A 1 77  ? 130.446 141.029 167.737 1.00 71.03  ? 100 LEU A CD2 1 
ATOM   597   N N   . ASP A 1 78  ? 127.956 144.941 170.431 1.00 49.07  ? 101 ASP A N   1 
ATOM   598   C CA  . ASP A 1 78  ? 127.992 146.307 170.947 1.00 49.07  ? 101 ASP A CA  1 
ATOM   599   C C   . ASP A 1 78  ? 128.761 146.378 172.262 1.00 49.07  ? 101 ASP A C   1 
ATOM   600   O O   . ASP A 1 78  ? 129.589 147.279 172.463 1.00 49.07  ? 101 ASP A O   1 
ATOM   601   C CB  . ASP A 1 78  ? 126.571 146.837 171.126 1.00 49.07  ? 101 ASP A CB  1 
ATOM   602   C CG  . ASP A 1 78  ? 126.528 148.342 171.304 1.00 49.07  ? 101 ASP A CG  1 
ATOM   603   O OD1 . ASP A 1 78  ? 127.583 148.992 171.145 1.00 49.07  ? 101 ASP A OD1 1 
ATOM   604   O OD2 . ASP A 1 78  ? 125.439 148.875 171.602 1.00 49.07  ? 101 ASP A OD2 1 
ATOM   605   N N   . ARG A 1 79  ? 128.502 145.434 173.170 1.00 41.98  ? 102 ARG A N   1 
ATOM   606   C CA  . ARG A 1 79  ? 129.221 145.422 174.442 1.00 41.98  ? 102 ARG A CA  1 
ATOM   607   C C   . ARG A 1 79  ? 130.715 145.195 174.232 1.00 41.98  ? 102 ARG A C   1 
ATOM   608   O O   . ARG A 1 79  ? 131.548 145.812 174.910 1.00 41.98  ? 102 ARG A O   1 
ATOM   609   C CB  . ARG A 1 79  ? 128.640 144.354 175.368 1.00 41.98  ? 102 ARG A CB  1 
ATOM   610   C CG  . ARG A 1 79  ? 127.221 144.644 175.832 1.00 41.98  ? 102 ARG A CG  1 
ATOM   611   C CD  . ARG A 1 79  ? 126.938 144.026 177.193 1.00 41.98  ? 102 ARG A CD  1 
ATOM   612   N NE  . ARG A 1 79  ? 126.979 142.567 177.161 1.00 41.98  ? 102 ARG A NE  1 
ATOM   613   C CZ  . ARG A 1 79  ? 127.974 141.836 177.654 1.00 41.98  ? 102 ARG A CZ  1 
ATOM   614   N NH1 . ARG A 1 79  ? 129.016 142.427 178.220 1.00 41.98  ? 102 ARG A NH1 1 
ATOM   615   N NH2 . ARG A 1 79  ? 127.926 140.513 177.581 1.00 41.98  ? 102 ARG A NH2 1 
ATOM   616   N N   . VAL A 1 80  ? 131.073 144.316 173.294 1.00 40.51  ? 103 VAL A N   1 
ATOM   617   C CA  . VAL A 1 80  ? 132.483 144.061 173.015 1.00 40.51  ? 103 VAL A CA  1 
ATOM   618   C C   . VAL A 1 80  ? 133.150 145.306 172.444 1.00 40.51  ? 103 VAL A C   1 
ATOM   619   O O   . VAL A 1 80  ? 134.292 145.630 172.793 1.00 40.51  ? 103 VAL A O   1 
ATOM   620   C CB  . VAL A 1 80  ? 132.630 142.852 172.073 1.00 40.51  ? 103 VAL A CB  1 
ATOM   621   C CG1 . VAL A 1 80  ? 134.043 142.771 171.523 1.00 40.51  ? 103 VAL A CG1 1 
ATOM   622   C CG2 . VAL A 1 80  ? 132.274 141.569 172.804 1.00 40.51  ? 103 VAL A CG2 1 
ATOM   623   N N   . LEU A 1 81  ? 132.452 146.025 171.561 1.00 37.91  ? 104 LEU A N   1 
ATOM   624   C CA  . LEU A 1 81  ? 132.991 147.275 171.033 1.00 37.91  ? 104 LEU A CA  1 
ATOM   625   C C   . LEU A 1 81  ? 133.215 148.290 172.145 1.00 37.91  ? 104 LEU A C   1 
ATOM   626   O O   . LEU A 1 81  ? 134.244 148.976 172.173 1.00 37.91  ? 104 LEU A O   1 
ATOM   627   C CB  . LEU A 1 81  ? 132.053 147.846 169.971 1.00 37.91  ? 104 LEU A CB  1 
ATOM   628   C CG  . LEU A 1 81  ? 132.261 147.360 168.537 1.00 37.91  ? 104 LEU A CG  1 
ATOM   629   C CD1 . LEU A 1 81  ? 131.202 147.944 167.619 1.00 37.91  ? 104 LEU A CD1 1 
ATOM   630   C CD2 . LEU A 1 81  ? 133.654 147.720 168.050 1.00 37.91  ? 104 LEU A CD2 1 
ATOM   631   N N   . TYR A 1 82  ? 132.259 148.401 173.071 1.00 35.54  ? 105 TYR A N   1 
ATOM   632   C CA  . TYR A 1 82  ? 132.423 149.327 174.188 1.00 35.54  ? 105 TYR A CA  1 
ATOM   633   C C   . TYR A 1 82  ? 133.628 148.954 175.045 1.00 35.54  ? 105 TYR A C   1 
ATOM   634   O O   . TYR A 1 82  ? 134.418 149.824 175.439 1.00 35.54  ? 105 TYR A O   1 
ATOM   635   C CB  . TYR A 1 82  ? 131.151 149.359 175.035 1.00 35.54  ? 105 TYR A CB  1 
ATOM   636   C CG  . TYR A 1 82  ? 131.259 150.230 176.266 1.00 35.54  ? 105 TYR A CG  1 
ATOM   637   C CD1 . TYR A 1 82  ? 131.452 149.670 177.522 1.00 35.54  ? 105 TYR A CD1 1 
ATOM   638   C CD2 . TYR A 1 82  ? 131.169 151.612 176.171 1.00 35.54  ? 105 TYR A CD2 1 
ATOM   639   C CE1 . TYR A 1 82  ? 131.551 150.462 178.649 1.00 35.54  ? 105 TYR A CE1 1 
ATOM   640   C CE2 . TYR A 1 82  ? 131.267 152.412 177.293 1.00 35.54  ? 105 TYR A CE2 1 
ATOM   641   C CZ  . TYR A 1 82  ? 131.459 151.832 178.529 1.00 35.54  ? 105 TYR A CZ  1 
ATOM   642   O OH  . TYR A 1 82  ? 131.557 152.625 179.649 1.00 35.54  ? 105 TYR A OH  1 
ATOM   643   N N   . GLN A 1 83  ? 133.788 147.662 175.345 1.00 33.86  ? 106 GLN A N   1 
ATOM   644   C CA  . GLN A 1 83  ? 134.917 147.233 176.166 1.00 33.86  ? 106 GLN A CA  1 
ATOM   645   C C   . GLN A 1 83  ? 136.246 147.473 175.457 1.00 33.86  ? 106 GLN A C   1 
ATOM   646   O O   . GLN A 1 83  ? 137.231 147.872 176.091 1.00 33.86  ? 106 GLN A O   1 
ATOM   647   C CB  . GLN A 1 83  ? 134.766 145.759 176.540 1.00 33.86  ? 106 GLN A CB  1 
ATOM   648   C CG  . GLN A 1 83  ? 133.575 145.463 177.435 1.00 33.86  ? 106 GLN A CG  1 
ATOM   649   C CD  . GLN A 1 83  ? 133.742 146.020 178.834 1.00 33.86  ? 106 GLN A CD  1 
ATOM   650   O OE1 . GLN A 1 83  ? 134.858 146.283 179.281 1.00 33.86  ? 106 GLN A OE1 1 
ATOM   651   N NE2 . GLN A 1 83  ? 132.629 146.204 179.533 1.00 33.86  ? 106 GLN A NE2 1 
ATOM   652   N N   . LEU A 1 84  ? 136.294 147.239 174.144 1.00 35.40  ? 107 LEU A N   1 
ATOM   653   C CA  . LEU A 1 84  ? 137.523 147.494 173.400 1.00 35.40  ? 107 LEU A CA  1 
ATOM   654   C C   . LEU A 1 84  ? 137.844 148.982 173.361 1.00 35.40  ? 107 LEU A C   1 
ATOM   655   O O   . LEU A 1 84  ? 139.014 149.373 173.449 1.00 35.40  ? 107 LEU A O   1 
ATOM   656   C CB  . LEU A 1 84  ? 137.411 146.931 171.984 1.00 35.40  ? 107 LEU A CB  1 
ATOM   657   C CG  . LEU A 1 84  ? 137.536 145.412 171.856 1.00 35.40  ? 107 LEU A CG  1 
ATOM   658   C CD1 . LEU A 1 84  ? 137.531 144.995 170.395 1.00 35.40  ? 107 LEU A CD1 1 
ATOM   659   C CD2 . LEU A 1 84  ? 138.791 144.919 172.556 1.00 35.40  ? 107 LEU A CD2 1 
ATOM   660   N N   . ASP A 1 85  ? 136.819 149.829 173.237 1.00 41.51  ? 108 ASP A N   1 
ATOM   661   C CA  . ASP A 1 85  ? 137.048 151.269 173.290 1.00 41.51  ? 108 ASP A CA  1 
ATOM   662   C C   . ASP A 1 85  ? 137.587 151.687 174.651 1.00 41.51  ? 108 ASP A C   1 
ATOM   663   O O   . ASP A 1 85  ? 138.477 152.541 174.741 1.00 41.51  ? 108 ASP A O   1 
ATOM   664   C CB  . ASP A 1 85  ? 135.756 152.019 172.969 1.00 41.51  ? 108 ASP A CB  1 
ATOM   665   C CG  . ASP A 1 85  ? 135.993 153.484 172.664 1.00 41.51  ? 108 ASP A CG  1 
ATOM   666   O OD1 . ASP A 1 85  ? 137.167 153.874 172.490 1.00 41.51  ? 108 ASP A OD1 1 
ATOM   667   O OD2 . ASP A 1 85  ? 135.006 154.247 172.599 1.00 41.51  ? 108 ASP A OD2 1 
ATOM   668   N N   . ALA A 1 86  ? 137.059 151.094 175.725 1.00 39.69  ? 109 ALA A N   1 
ATOM   669   C CA  . ALA A 1 86  ? 137.573 151.397 177.058 1.00 39.69  ? 109 ALA A CA  1 
ATOM   670   C C   . ALA A 1 86  ? 139.029 150.966 177.201 1.00 39.69  ? 109 ALA A C   1 
ATOM   671   O O   . ALA A 1 86  ? 139.854 151.704 177.756 1.00 39.69  ? 109 ALA A O   1 
ATOM   672   C CB  . ALA A 1 86  ? 136.707 150.725 178.122 1.00 39.69  ? 109 ALA A CB  1 
ATOM   673   N N   . LEU A 1 87  ? 139.365 149.774 176.703 1.00 39.70  ? 110 LEU A N   1 
ATOM   674   C CA  . LEU A 1 87  ? 140.748 149.311 176.774 1.00 39.70  ? 110 LEU A CA  1 
ATOM   675   C C   . LEU A 1 87  ? 141.674 150.212 175.966 1.00 39.70  ? 110 LEU A C   1 
ATOM   676   O O   . LEU A 1 87  ? 142.811 150.477 176.376 1.00 39.70  ? 110 LEU A O   1 
ATOM   677   C CB  . LEU A 1 87  ? 140.846 147.865 176.289 1.00 39.70  ? 110 LEU A CB  1 
ATOM   678   C CG  . LEU A 1 87  ? 142.250 147.257 176.279 1.00 39.70  ? 110 LEU A CG  1 
ATOM   679   C CD1 . LEU A 1 87  ? 142.853 147.281 177.673 1.00 39.70  ? 110 LEU A CD1 1 
ATOM   680   C CD2 . LEU A 1 87  ? 142.219 145.841 175.728 1.00 39.70  ? 110 LEU A CD2 1 
ATOM   681   N N   . ARG A 1 88  ? 141.203 150.698 174.815 1.00 41.34  ? 111 ARG A N   1 
ATOM   682   C CA  . ARG A 1 88  ? 142.012 151.610 174.014 1.00 41.34  ? 111 ARG A CA  1 
ATOM   683   C C   . ARG A 1 88  ? 142.218 152.938 174.730 1.00 41.34  ? 111 ARG A C   1 
ATOM   684   O O   . ARG A 1 88  ? 143.323 153.491 174.720 1.00 41.34  ? 111 ARG A O   1 
ATOM   685   C CB  . ARG A 1 88  ? 141.357 151.835 172.651 1.00 41.34  ? 111 ARG A CB  1 
ATOM   686   C CG  . ARG A 1 88  ? 142.160 152.724 171.718 1.00 41.34  ? 111 ARG A CG  1 
ATOM   687   C CD  . ARG A 1 88  ? 141.534 152.776 170.335 1.00 41.34  ? 111 ARG A CD  1 
ATOM   688   N NE  . ARG A 1 88  ? 142.296 153.621 169.421 1.00 41.34  ? 111 ARG A NE  1 
ATOM   689   C CZ  . ARG A 1 88  ? 142.011 153.772 168.132 1.00 41.34  ? 111 ARG A CZ  1 
ATOM   690   N NH1 . ARG A 1 88  ? 142.760 154.561 167.373 1.00 41.34  ? 111 ARG A NH1 1 
ATOM   691   N NH2 . ARG A 1 88  ? 140.979 153.133 167.600 1.00 41.34  ? 111 ARG A NH2 1 
ATOM   692   N N   . GLN A 1 89  ? 141.164 153.464 175.357 1.00 48.60  ? 112 GLN A N   1 
ATOM   693   C CA  . GLN A 1 89  ? 141.276 154.712 176.100 1.00 48.60  ? 112 GLN A CA  1 
ATOM   694   C C   . GLN A 1 89  ? 142.061 154.557 177.395 1.00 48.60  ? 112 GLN A C   1 
ATOM   695   O O   . GLN A 1 89  ? 142.432 155.571 177.995 1.00 48.60  ? 112 GLN A O   1 
ATOM   696   C CB  . GLN A 1 89  ? 139.884 155.268 176.405 1.00 48.60  ? 112 GLN A CB  1 
ATOM   697   C CG  . GLN A 1 89  ? 139.334 156.184 175.325 1.00 48.60  ? 112 GLN A CG  1 
ATOM   698   C CD  . GLN A 1 89  ? 140.048 157.519 175.273 1.00 48.60  ? 112 GLN A CD  1 
ATOM   699   O OE1 . GLN A 1 89  ? 140.690 157.931 176.239 1.00 48.60  ? 112 GLN A OE1 1 
ATOM   700   N NE2 . GLN A 1 89  ? 139.941 158.204 174.141 1.00 48.60  ? 112 GLN A NE2 1 
ATOM   701   N N   . LYS A 1 90  ? 142.292 153.328 177.853 1.00 43.58  ? 113 LYS A N   1 
ATOM   702   C CA  . LYS A 1 90  ? 143.114 153.097 179.035 1.00 43.58  ? 113 LYS A CA  1 
ATOM   703   C C   . LYS A 1 90  ? 144.571 152.783 178.718 1.00 43.58  ? 113 LYS A C   1 
ATOM   704   O O   . LYS A 1 90  ? 145.446 153.084 179.535 1.00 43.58  ? 113 LYS A O   1 
ATOM   705   C CB  . LYS A 1 90  ? 142.533 151.952 179.871 1.00 43.58  ? 113 LYS A CB  1 
ATOM   706   C CG  . LYS A 1 90  ? 141.350 152.351 180.734 1.00 43.58  ? 113 LYS A CG  1 
ATOM   707   C CD  . LYS A 1 90  ? 140.935 151.216 181.654 1.00 43.58  ? 113 LYS A CD  1 
ATOM   708   C CE  . LYS A 1 90  ? 139.854 151.660 182.623 1.00 43.58  ? 113 LYS A CE  1 
ATOM   709   N NZ  . LYS A 1 90  ? 139.466 150.568 183.558 1.00 43.58  ? 113 LYS A NZ  1 
ATOM   710   N N   . PHE A 1 91  ? 144.856 152.184 177.558 1.00 42.10  ? 114 PHE A N   1 
ATOM   711   C CA  . PHE A 1 91  ? 146.226 151.769 177.262 1.00 42.10  ? 114 PHE A CA  1 
ATOM   712   C C   . PHE A 1 91  ? 147.110 152.957 176.898 1.00 42.10  ? 114 PHE A C   1 
ATOM   713   O O   . PHE A 1 91  ? 148.287 152.997 177.277 1.00 42.10  ? 114 PHE A O   1 
ATOM   714   C CB  . PHE A 1 91  ? 146.227 150.735 176.138 1.00 42.10  ? 114 PHE A CB  1 
ATOM   715   C CG  . PHE A 1 91  ? 147.552 150.058 175.938 1.00 42.10  ? 114 PHE A CG  1 
ATOM   716   C CD1 . PHE A 1 91  ? 148.091 149.255 176.928 1.00 42.10  ? 114 PHE A CD1 1 
ATOM   717   C CD2 . PHE A 1 91  ? 148.256 150.219 174.757 1.00 42.10  ? 114 PHE A CD2 1 
ATOM   718   C CE1 . PHE A 1 91  ? 149.309 148.630 176.746 1.00 42.10  ? 114 PHE A CE1 1 
ATOM   719   C CE2 . PHE A 1 91  ? 149.474 149.595 174.569 1.00 42.10  ? 114 PHE A CE2 1 
ATOM   720   C CZ  . PHE A 1 91  ? 150.001 148.799 175.565 1.00 42.10  ? 114 PHE A CZ  1 
ATOM   721   N N   . LEU A 1 92  ? 146.570 153.919 176.145 1.00 49.98  ? 115 LEU A N   1 
ATOM   722   C CA  . LEU A 1 92  ? 147.276 155.153 175.781 1.00 49.98  ? 115 LEU A CA  1 
ATOM   723   C C   . LEU A 1 92  ? 148.496 154.882 174.902 1.00 49.98  ? 115 LEU A C   1 
ATOM   724   O O   . LEU A 1 92  ? 149.538 155.526 175.045 1.00 49.98  ? 115 LEU A O   1 
ATOM   725   C CB  . LEU A 1 92  ? 147.684 155.957 177.020 1.00 49.98  ? 115 LEU A CB  1 
ATOM   726   C CG  . LEU A 1 92  ? 146.683 156.961 177.594 1.00 49.98  ? 115 LEU A CG  1 
ATOM   727   C CD1 . LEU A 1 92  ? 146.314 158.012 176.557 1.00 49.98  ? 115 LEU A CD1 1 
ATOM   728   C CD2 . LEU A 1 92  ? 145.451 156.254 178.117 1.00 49.98  ? 115 LEU A CD2 1 
ATOM   729   N N   . LYS A 1 93  ? 148.374 153.923 173.982 1.00 58.82  ? 116 LYS A N   1 
ATOM   730   C CA  . LYS A 1 93  ? 149.423 153.704 172.985 1.00 58.82  ? 116 LYS A CA  1 
ATOM   731   C C   . LYS A 1 93  ? 148.786 153.021 171.774 1.00 58.82  ? 116 LYS A C   1 
ATOM   732   O O   . LYS A 1 93  ? 148.555 151.809 171.796 1.00 58.82  ? 116 LYS A O   1 
ATOM   733   C CB  . LYS A 1 93  ? 150.570 152.884 173.551 1.00 58.82  ? 116 LYS A CB  1 
ATOM   734   C CG  . LYS A 1 93  ? 151.896 153.628 173.553 1.00 58.82  ? 116 LYS A CG  1 
ATOM   735   C CD  . LYS A 1 93  ? 153.063 152.708 173.858 1.00 58.82  ? 116 LYS A CD  1 
ATOM   736   C CE  . LYS A 1 93  ? 154.376 153.472 173.840 1.00 58.82  ? 116 LYS A CE  1 
ATOM   737   N NZ  . LYS A 1 93  ? 155.544 152.586 174.092 1.00 58.82  ? 116 LYS A NZ  1 
ATOM   738   N N   . THR A 1 94  ? 148.513 153.806 170.737 1.00 70.55  ? 117 THR A N   1 
ATOM   739   C CA  . THR A 1 94  ? 147.941 153.298 169.495 1.00 70.55  ? 117 THR A CA  1 
ATOM   740   C C   . THR A 1 94  ? 148.970 152.663 168.555 1.00 70.55  ? 117 THR A C   1 
ATOM   741   O O   . THR A 1 94  ? 148.676 151.609 167.976 1.00 70.55  ? 117 THR A O   1 
ATOM   742   C CB  . THR A 1 94  ? 147.178 154.411 168.766 1.00 70.55  ? 117 THR A CB  1 
ATOM   743   O OG1 . THR A 1 94  ? 148.089 155.245 168.039 1.00 70.55  ? 117 THR A OG1 1 
ATOM   744   C CG2 . THR A 1 94  ? 146.405 155.265 169.760 1.00 70.55  ? 117 THR A CG2 1 
ATOM   745   N N   . PRO A 1 95  ? 150.167 153.240 168.355 1.00 69.84  ? 118 PRO A N   1 
ATOM   746   C CA  . PRO A 1 95  ? 151.050 152.686 167.314 1.00 69.84  ? 118 PRO A CA  1 
ATOM   747   C C   . PRO A 1 95  ? 151.613 151.318 167.657 1.00 69.84  ? 118 PRO A C   1 
ATOM   748   O O   . PRO A 1 95  ? 151.931 150.549 166.741 1.00 69.84  ? 118 PRO A O   1 
ATOM   749   C CB  . PRO A 1 95  ? 152.168 153.736 167.194 1.00 69.84  ? 118 PRO A CB  1 
ATOM   750   C CG  . PRO A 1 95  ? 151.691 154.928 167.963 1.00 69.84  ? 118 PRO A CG  1 
ATOM   751   C CD  . PRO A 1 95  ? 150.825 154.369 169.034 1.00 69.84  ? 118 PRO A CD  1 
ATOM   752   N N   . ALA A 1 96  ? 151.752 150.989 168.939 1.00 64.69  ? 119 ALA A N   1 
ATOM   753   C CA  . ALA A 1 96  ? 152.348 149.723 169.344 1.00 64.69  ? 119 ALA A CA  1 
ATOM   754   C C   . ALA A 1 96  ? 151.353 148.571 169.367 1.00 64.69  ? 119 ALA A C   1 
ATOM   755   O O   . ALA A 1 96  ? 151.696 147.494 169.868 1.00 64.69  ? 119 ALA A O   1 
ATOM   756   C CB  . ALA A 1 96  ? 153.001 149.865 170.723 1.00 64.69  ? 119 ALA A CB  1 
ATOM   757   N N   . PHE A 1 97  ? 150.145 148.758 168.837 1.00 56.50  ? 120 PHE A N   1 
ATOM   758   C CA  . PHE A 1 97  ? 149.135 147.713 168.941 1.00 56.50  ? 120 PHE A CA  1 
ATOM   759   C C   . PHE A 1 97  ? 148.044 147.918 167.893 1.00 56.50  ? 120 PHE A C   1 
ATOM   760   O O   . PHE A 1 97  ? 146.936 148.357 168.227 1.00 56.50  ? 120 PHE A O   1 
ATOM   761   C CB  . PHE A 1 97  ? 148.556 147.708 170.360 1.00 56.50  ? 120 PHE A CB  1 
ATOM   762   C CG  . PHE A 1 97  ? 147.652 146.543 170.659 1.00 56.50  ? 120 PHE A CG  1 
ATOM   763   C CD1 . PHE A 1 97  ? 148.175 145.275 170.823 1.00 56.50  ? 120 PHE A CD1 1 
ATOM   764   C CD2 . PHE A 1 97  ? 146.292 146.723 170.827 1.00 56.50  ? 120 PHE A CD2 1 
ATOM   765   C CE1 . PHE A 1 97  ? 147.357 144.203 171.113 1.00 56.50  ? 120 PHE A CE1 1 
ATOM   766   C CE2 . PHE A 1 97  ? 145.468 145.649 171.119 1.00 56.50  ? 120 PHE A CE2 1 
ATOM   767   C CZ  . PHE A 1 97  ? 146.003 144.392 171.263 1.00 56.50  ? 120 PHE A CZ  1 
ATOM   768   N N   . PRO A 1 98  ? 148.316 147.618 166.615 1.00 53.24  ? 121 PRO A N   1 
ATOM   769   C CA  . PRO A 1 98  ? 147.291 147.816 165.576 1.00 53.24  ? 121 PRO A CA  1 
ATOM   770   C C   . PRO A 1 98  ? 146.262 146.702 165.503 1.00 53.24  ? 121 PRO A C   1 
ATOM   771   O O   . PRO A 1 98  ? 145.224 146.879 164.843 1.00 53.24  ? 121 PRO A O   1 
ATOM   772   C CB  . PRO A 1 98  ? 148.116 147.882 164.284 1.00 53.24  ? 121 PRO A CB  1 
ATOM   773   C CG  . PRO A 1 98  ? 149.297 147.023 164.573 1.00 53.24  ? 121 PRO A CG  1 
ATOM   774   C CD  . PRO A 1 98  ? 149.600 147.173 166.045 1.00 53.24  ? 121 PRO A CD  1 
ATOM   775   N N   . LYS A 1 99  ? 146.525 145.560 166.142 1.00 49.62  ? 122 LYS A N   1 
ATOM   776   C CA  . LYS A 1 99  ? 145.538 144.489 166.176 1.00 49.62  ? 122 LYS A CA  1 
ATOM   777   C C   . LYS A 1 99  ? 144.221 144.965 166.776 1.00 49.62  ? 122 LYS A C   1 
ATOM   778   O O   . LYS A 1 99  ? 143.161 144.433 166.433 1.00 49.62  ? 122 LYS A O   1 
ATOM   779   C CB  . LYS A 1 99  ? 146.088 143.295 166.956 1.00 49.62  ? 122 LYS A CB  1 
ATOM   780   C CG  . LYS A 1 99  ? 147.353 142.691 166.360 1.00 49.62  ? 122 LYS A CG  1 
ATOM   781   C CD  . LYS A 1 99  ? 147.087 142.089 164.988 1.00 49.62  ? 122 LYS A CD  1 
ATOM   782   C CE  . LYS A 1 99  ? 148.329 141.416 164.416 1.00 49.62  ? 122 LYS A CE  1 
ATOM   783   N NZ  . LYS A 1 99  ? 148.054 140.742 163.113 1.00 49.62  ? 122 LYS A NZ  1 
ATOM   784   N N   . LEU A 1 100 ? 144.262 145.976 167.647 1.00 49.06  ? 123 LEU A N   1 
ATOM   785   C CA  . LEU A 1 100 ? 143.028 146.542 168.186 1.00 49.06  ? 123 LEU A CA  1 
ATOM   786   C C   . LEU A 1 100 ? 142.195 147.191 167.089 1.00 49.06  ? 123 LEU A C   1 
ATOM   787   O O   . LEU A 1 100 ? 140.982 146.968 167.003 1.00 49.06  ? 123 LEU A O   1 
ATOM   788   C CB  . LEU A 1 100 ? 143.348 147.557 169.281 1.00 49.06  ? 123 LEU A CB  1 
ATOM   789   C CG  . LEU A 1 100 ? 142.207 148.065 170.161 1.00 49.06  ? 123 LEU A CG  1 
ATOM   790   C CD1 . LEU A 1 100 ? 141.376 146.906 170.666 1.00 49.06  ? 123 LEU A CD1 1 
ATOM   791   C CD2 . LEU A 1 100 ? 142.791 148.833 171.325 1.00 49.06  ? 123 LEU A CD2 1 
ATOM   792   N N   . ASP A 1 101 ? 142.825 148.015 166.248 1.00 50.78  ? 124 ASP A N   1 
ATOM   793   C CA  . ASP A 1 101 ? 142.093 148.630 165.146 1.00 50.78  ? 124 ASP A CA  1 
ATOM   794   C C   . ASP A 1 101 ? 141.604 147.581 164.157 1.00 50.78  ? 124 ASP A C   1 
ATOM   795   O O   . ASP A 1 101 ? 140.490 147.690 163.626 1.00 50.78  ? 124 ASP A O   1 
ATOM   796   C CB  . ASP A 1 101 ? 142.968 149.663 164.438 1.00 50.78  ? 124 ASP A CB  1 
ATOM   797   C CG  . ASP A 1 101 ? 143.288 150.851 165.316 1.00 50.78  ? 124 ASP A CG  1 
ATOM   798   O OD1 . ASP A 1 101 ? 142.437 151.217 166.153 1.00 50.78  ? 124 ASP A OD1 1 
ATOM   799   O OD2 . ASP A 1 101 ? 144.393 151.416 165.172 1.00 50.78  ? 124 ASP A OD2 1 
ATOM   800   N N   . SER A 1 102 ? 142.421 146.556 163.899 1.00 44.11  ? 125 SER A N   1 
ATOM   801   C CA  . SER A 1 102 ? 142.000 145.496 162.985 1.00 44.11  ? 125 SER A CA  1 
ATOM   802   C C   . SER A 1 102 ? 140.763 144.775 163.511 1.00 44.11  ? 125 SER A C   1 
ATOM   803   O O   . SER A 1 102 ? 139.787 144.567 162.776 1.00 44.11  ? 125 SER A O   1 
ATOM   804   C CB  . SER A 1 102 ? 143.145 144.510 162.758 1.00 44.11  ? 125 SER A CB  1 
ATOM   805   O OG  . SER A 1 102 ? 144.361 145.191 162.505 1.00 44.11  ? 125 SER A OG  1 
ATOM   806   N N   . ALA A 1 103 ? 140.783 144.391 164.791 1.00 46.67  ? 126 ALA A N   1 
ATOM   807   C CA  . ALA A 1 103 ? 139.637 143.712 165.382 1.00 46.67  ? 126 ALA A CA  1 
ATOM   808   C C   . ALA A 1 103 ? 138.420 144.625 165.440 1.00 46.67  ? 126 ALA A C   1 
ATOM   809   O O   . ALA A 1 103 ? 137.288 144.166 165.258 1.00 46.67  ? 126 ALA A O   1 
ATOM   810   C CB  . ALA A 1 103 ? 139.991 143.201 166.778 1.00 46.67  ? 126 ALA A CB  1 
ATOM   811   N N   . ARG A 1 104 ? 138.629 145.921 165.691 1.00 42.52  ? 127 ARG A N   1 
ATOM   812   C CA  . ARG A 1 104 ? 137.510 146.857 165.715 1.00 42.52  ? 127 ARG A CA  1 
ATOM   813   C C   . ARG A 1 104 ? 136.843 146.951 164.350 1.00 42.52  ? 127 ARG A C   1 
ATOM   814   O O   . ARG A 1 104 ? 135.609 146.929 164.248 1.00 42.52  ? 127 ARG A O   1 
ATOM   815   C CB  . ARG A 1 104 ? 137.989 148.232 166.176 1.00 42.52  ? 127 ARG A CB  1 
ATOM   816   C CG  . ARG A 1 104 ? 136.872 149.227 166.433 1.00 42.52  ? 127 ARG A CG  1 
ATOM   817   C CD  . ARG A 1 104 ? 137.405 150.497 167.077 1.00 42.52  ? 127 ARG A CD  1 
ATOM   818   N NE  . ARG A 1 104 ? 136.336 151.434 167.403 1.00 42.52  ? 127 ARG A NE  1 
ATOM   819   C CZ  . ARG A 1 104 ? 135.931 152.415 166.602 1.00 42.52  ? 127 ARG A CZ  1 
ATOM   820   N NH1 . ARG A 1 104 ? 134.948 153.218 166.984 1.00 42.52  ? 127 ARG A NH1 1 
ATOM   821   N NH2 . ARG A 1 104 ? 136.510 152.595 165.423 1.00 42.52  ? 127 ARG A NH2 1 
ATOM   822   N N   . HIS A 1 105 ? 137.644 147.048 163.286 1.00 44.04  ? 128 HIS A N   1 
ATOM   823   C CA  . HIS A 1 105 ? 137.078 147.088 161.942 1.00 44.04  ? 128 HIS A CA  1 
ATOM   824   C C   . HIS A 1 105 ? 136.372 145.781 161.601 1.00 44.04  ? 128 HIS A C   1 
ATOM   825   O O   . HIS A 1 105 ? 135.306 145.788 160.971 1.00 44.04  ? 128 HIS A O   1 
ATOM   826   C CB  . HIS A 1 105 ? 138.173 147.393 160.921 1.00 44.04  ? 128 HIS A CB  1 
ATOM   827   C CG  . HIS A 1 105 ? 138.509 148.847 160.815 1.00 44.04  ? 128 HIS A CG  1 
ATOM   828   N ND1 . HIS A 1 105 ? 137.720 149.745 160.129 1.00 44.04  ? 128 HIS A ND1 1 
ATOM   829   C CD2 . HIS A 1 105 ? 139.548 149.561 161.310 1.00 44.04  ? 128 HIS A CD2 1 
ATOM   830   C CE1 . HIS A 1 105 ? 138.259 150.949 160.206 1.00 44.04  ? 128 HIS A CE1 1 
ATOM   831   N NE2 . HIS A 1 105 ? 139.368 150.865 160.917 1.00 44.04  ? 128 HIS A NE2 1 
ATOM   832   N N   . ASN A 1 106 ? 136.944 144.646 162.013 1.00 41.88  ? 129 ASN A N   1 
ATOM   833   C CA  . ASN A 1 106 ? 136.296 143.363 161.754 1.00 41.88  ? 129 ASN A CA  1 
ATOM   834   C C   . ASN A 1 106 ? 134.955 143.263 162.473 1.00 41.88  ? 129 ASN A C   1 
ATOM   835   O O   . ASN A 1 106 ? 133.973 142.764 161.908 1.00 41.88  ? 129 ASN A O   1 
ATOM   836   C CB  . ASN A 1 106 ? 137.217 142.217 162.169 1.00 41.88  ? 129 ASN A CB  1 
ATOM   837   C CG  . ASN A 1 106 ? 138.420 142.078 161.260 1.00 41.88  ? 129 ASN A CG  1 
ATOM   838   O OD1 . ASN A 1 106 ? 138.727 142.975 160.476 1.00 41.88  ? 129 ASN A OD1 1 
ATOM   839   N ND2 . ASN A 1 106 ? 139.112 140.949 161.362 1.00 41.88  ? 129 ASN A ND2 1 
ATOM   840   N N   . ILE A 1 107 ? 134.892 143.737 163.718 1.00 41.43  ? 130 ILE A N   1 
ATOM   841   C CA  . ILE A 1 107 ? 133.640 143.694 164.467 1.00 41.43  ? 130 ILE A CA  1 
ATOM   842   C C   . ILE A 1 107 ? 132.613 144.629 163.844 1.00 41.43  ? 130 ILE A C   1 
ATOM   843   O O   . ILE A 1 107 ? 131.421 144.306 163.777 1.00 41.43  ? 130 ILE A O   1 
ATOM   844   C CB  . ILE A 1 107 ? 133.892 144.027 165.948 1.00 41.43  ? 130 ILE A CB  1 
ATOM   845   C CG1 . ILE A 1 107 ? 134.718 142.923 166.606 1.00 41.43  ? 130 ILE A CG1 1 
ATOM   846   C CG2 . ILE A 1 107 ? 132.580 144.202 166.690 1.00 41.43  ? 130 ILE A CG2 1 
ATOM   847   C CD1 . ILE A 1 107 ? 135.130 143.237 168.024 1.00 41.43  ? 130 ILE A CD1 1 
ATOM   848   N N   . LEU A 1 108 ? 133.051 145.799 163.370 1.00 44.45  ? 131 LEU A N   1 
ATOM   849   C CA  . LEU A 1 108 ? 132.130 146.697 162.681 1.00 44.45  ? 131 LEU A CA  1 
ATOM   850   C C   . LEU A 1 108 ? 131.580 146.052 161.413 1.00 44.45  ? 131 LEU A C   1 
ATOM   851   O O   . LEU A 1 108 ? 130.387 146.176 161.108 1.00 44.45  ? 131 LEU A O   1 
ATOM   852   C CB  . LEU A 1 108 ? 132.827 148.017 162.356 1.00 44.45  ? 131 LEU A CB  1 
ATOM   853   C CG  . LEU A 1 108 ? 133.050 148.960 163.538 1.00 44.45  ? 131 LEU A CG  1 
ATOM   854   C CD1 . LEU A 1 108 ? 133.824 150.192 163.103 1.00 44.45  ? 131 LEU A CD1 1 
ATOM   855   C CD2 . LEU A 1 108 ? 131.723 149.351 164.166 1.00 44.45  ? 131 LEU A CD2 1 
ATOM   856   N N   . GLY A 1 109 ? 132.436 145.352 160.667 1.00 43.21  ? 132 GLY A N   1 
ATOM   857   C CA  . GLY A 1 109 ? 131.966 144.654 159.481 1.00 43.21  ? 132 GLY A CA  1 
ATOM   858   C C   . GLY A 1 109 ? 130.971 143.556 159.805 1.00 43.21  ? 132 GLY A C   1 
ATOM   859   O O   . GLY A 1 109 ? 129.963 143.393 159.112 1.00 43.21  ? 132 GLY A O   1 
ATOM   860   N N   . ILE A 1 110 ? 131.243 142.785 160.861 1.00 39.60  ? 133 ILE A N   1 
ATOM   861   C CA  . ILE A 1 110 ? 130.316 141.732 161.270 1.00 39.60  ? 133 ILE A CA  1 
ATOM   862   C C   . ILE A 1 110 ? 128.985 142.335 161.705 1.00 39.60  ? 133 ILE A C   1 
ATOM   863   O O   . ILE A 1 110 ? 127.913 141.783 161.425 1.00 39.60  ? 133 ILE A O   1 
ATOM   864   C CB  . ILE A 1 110 ? 130.941 140.870 162.383 1.00 39.60  ? 133 ILE A CB  1 
ATOM   865   C CG1 . ILE A 1 110 ? 132.167 140.125 161.855 1.00 39.60  ? 133 ILE A CG1 1 
ATOM   866   C CG2 . ILE A 1 110 ? 129.927 139.881 162.931 1.00 39.60  ? 133 ILE A CG2 1 
ATOM   867   C CD1 . ILE A 1 110 ? 132.861 139.281 162.899 1.00 39.60  ? 133 ILE A CD1 1 
ATOM   868   N N   . ARG A 1 111 ? 129.032 143.482 162.386 1.00 43.13  ? 134 ARG A N   1 
ATOM   869   C CA  . ARG A 1 111 ? 127.804 144.153 162.798 1.00 43.13  ? 134 ARG A CA  1 
ATOM   870   C C   . ARG A 1 111 ? 127.000 144.614 161.590 1.00 43.13  ? 134 ARG A C   1 
ATOM   871   O O   . ARG A 1 111 ? 125.775 144.450 161.548 1.00 43.13  ? 134 ARG A O   1 
ATOM   872   C CB  . ARG A 1 111 ? 128.141 145.337 163.704 1.00 43.13  ? 134 ARG A CB  1 
ATOM   873   C CG  . ARG A 1 111 ? 127.100 145.639 164.766 1.00 43.13  ? 134 ARG A CG  1 
ATOM   874   C CD  . ARG A 1 111 ? 127.716 146.426 165.911 1.00 43.13  ? 134 ARG A CD  1 
ATOM   875   N NE  . ARG A 1 111 ? 126.743 146.748 166.948 1.00 43.13  ? 134 ARG A NE  1 
ATOM   876   C CZ  . ARG A 1 111 ? 126.192 147.947 167.106 1.00 43.13  ? 134 ARG A CZ  1 
ATOM   877   N NH1 . ARG A 1 111 ? 126.520 148.940 166.292 1.00 43.13  ? 134 ARG A NH1 1 
ATOM   878   N NH2 . ARG A 1 111 ? 125.316 148.154 168.079 1.00 43.13  ? 134 ARG A NH2 1 
ATOM   879   N N   . ASN A 1 112 ? 127.675 145.191 160.593 1.00 40.31  ? 135 ASN A N   1 
ATOM   880   C CA  . ASN A 1 112 ? 126.985 145.595 159.371 1.00 40.31  ? 135 ASN A CA  1 
ATOM   881   C C   . ASN A 1 112 ? 126.357 144.394 158.672 1.00 40.31  ? 135 ASN A C   1 
ATOM   882   O O   . ASN A 1 112 ? 125.208 144.460 158.213 1.00 40.31  ? 135 ASN A O   1 
ATOM   883   C CB  . ASN A 1 112 ? 127.957 146.313 158.436 1.00 40.31  ? 135 ASN A CB  1 
ATOM   884   C CG  . ASN A 1 112 ? 127.347 146.622 157.085 1.00 40.31  ? 135 ASN A CG  1 
ATOM   885   O OD1 . ASN A 1 112 ? 126.155 146.911 156.981 1.00 40.31  ? 135 ASN A OD1 1 
ATOM   886   N ND2 . ASN A 1 112 ? 128.163 146.560 156.040 1.00 40.31  ? 135 ASN A ND2 1 
ATOM   887   N N   . ASN A 1 113 ? 127.094 143.284 158.592 1.00 42.53  ? 136 ASN A N   1 
ATOM   888   C CA  . ASN A 1 113 ? 126.574 142.098 157.919 1.00 42.53  ? 136 ASN A CA  1 
ATOM   889   C C   . ASN A 1 113 ? 125.358 141.536 158.645 1.00 42.53  ? 136 ASN A C   1 
ATOM   890   O O   . ASN A 1 113 ? 124.365 141.163 158.009 1.00 42.53  ? 136 ASN A O   1 
ATOM   891   C CB  . ASN A 1 113 ? 127.667 141.036 157.805 1.00 42.53  ? 136 ASN A CB  1 
ATOM   892   C CG  . ASN A 1 113 ? 128.554 141.242 156.595 1.00 42.53  ? 136 ASN A CG  1 
ATOM   893   O OD1 . ASN A 1 113 ? 128.105 141.728 155.558 1.00 42.53  ? 136 ASN A OD1 1 
ATOM   894   N ND2 . ASN A 1 113 ? 129.822 140.871 156.722 1.00 42.53  ? 136 ASN A ND2 1 
ATOM   895   N N   . VAL A 1 114 ? 125.411 141.472 159.978 1.00 44.68  ? 137 VAL A N   1 
ATOM   896   C CA  . VAL A 1 114 ? 124.280 140.914 160.713 1.00 44.68  ? 137 VAL A CA  1 
ATOM   897   C C   . VAL A 1 114 ? 123.085 141.859 160.658 1.00 44.68  ? 137 VAL A C   1 
ATOM   898   O O   . VAL A 1 114 ? 121.935 141.406 160.616 1.00 44.68  ? 137 VAL A O   1 
ATOM   899   C CB  . VAL A 1 114 ? 124.682 140.569 162.161 1.00 44.68  ? 137 VAL A CB  1 
ATOM   900   C CG1 . VAL A 1 114 ? 124.915 141.820 162.988 1.00 44.68  ? 137 VAL A CG1 1 
ATOM   901   C CG2 . VAL A 1 114 ? 123.625 139.690 162.808 1.00 44.68  ? 137 VAL A CG2 1 
ATOM   902   N N   . PHE A 1 115 ? 123.323 143.173 160.614 1.00 45.05  ? 138 PHE A N   1 
ATOM   903   C CA  . PHE A 1 115 ? 122.211 144.104 160.452 1.00 45.05  ? 138 PHE A CA  1 
ATOM   904   C C   . PHE A 1 115 ? 121.548 143.935 159.093 1.00 45.05  ? 138 PHE A C   1 
ATOM   905   O O   . PHE A 1 115 ? 120.315 143.943 158.991 1.00 45.05  ? 138 PHE A O   1 
ATOM   906   C CB  . PHE A 1 115 ? 122.690 145.544 160.633 1.00 45.05  ? 138 PHE A CB  1 
ATOM   907   C CG  . PHE A 1 115 ? 121.740 146.568 160.082 1.00 45.05  ? 138 PHE A CG  1 
ATOM   908   C CD1 . PHE A 1 115 ? 122.030 147.242 158.909 1.00 45.05  ? 138 PHE A CD1 1 
ATOM   909   C CD2 . PHE A 1 115 ? 120.551 146.849 160.734 1.00 45.05  ? 138 PHE A CD2 1 
ATOM   910   C CE1 . PHE A 1 115 ? 121.155 148.181 158.399 1.00 45.05  ? 138 PHE A CE1 1 
ATOM   911   C CE2 . PHE A 1 115 ? 119.673 147.787 160.229 1.00 45.05  ? 138 PHE A CE2 1 
ATOM   912   C CZ  . PHE A 1 115 ? 119.975 148.454 159.060 1.00 45.05  ? 138 PHE A CZ  1 
ATOM   913   N N   . CYS A 1 116 ? 122.348 143.778 158.036 1.00 50.24  ? 139 CYS A N   1 
ATOM   914   C CA  . CYS A 1 116 ? 121.773 143.568 156.710 1.00 50.24  ? 139 CYS A CA  1 
ATOM   915   C C   . CYS A 1 116 ? 121.014 142.248 156.641 1.00 50.24  ? 139 CYS A C   1 
ATOM   916   O O   . CYS A 1 116 ? 119.942 142.173 156.028 1.00 50.24  ? 139 CYS A O   1 
ATOM   917   C CB  . CYS A 1 116 ? 122.871 143.618 155.651 1.00 50.24  ? 139 CYS A CB  1 
ATOM   918   S SG  . CYS A 1 116 ? 123.624 145.246 155.455 1.00 50.24  ? 139 CYS A SG  1 
ATOM   919   N N   . MET A 1 117 ? 121.551 141.200 157.269 1.00 46.33  ? 140 MET A N   1 
ATOM   920   C CA  . MET A 1 117 ? 120.857 139.916 157.291 1.00 46.33  ? 140 MET A CA  1 
ATOM   921   C C   . MET A 1 117 ? 119.534 140.017 158.040 1.00 46.33  ? 140 MET A C   1 
ATOM   922   O O   . MET A 1 117 ? 118.531 139.424 157.627 1.00 46.33  ? 140 MET A O   1 
ATOM   923   C CB  . MET A 1 117 ? 121.752 138.848 157.919 1.00 46.33  ? 140 MET A CB  1 
ATOM   924   C CG  . MET A 1 117 ? 121.066 137.511 158.142 1.00 46.33  ? 140 MET A CG  1 
ATOM   925   S SD  . MET A 1 117 ? 120.501 136.755 156.607 1.00 46.33  ? 140 MET A SD  1 
ATOM   926   C CE  . MET A 1 117 ? 122.066 136.396 155.815 1.00 46.33  ? 140 MET A CE  1 
ATOM   927   N N   . ALA A 1 118 ? 119.511 140.767 159.145 1.00 58.79  ? 141 ALA A N   1 
ATOM   928   C CA  . ALA A 1 118 ? 118.264 140.957 159.878 1.00 58.79  ? 141 ALA A CA  1 
ATOM   929   C C   . ALA A 1 118 ? 117.266 141.770 159.064 1.00 58.79  ? 141 ALA A C   1 
ATOM   930   O O   . ALA A 1 118 ? 116.058 141.513 159.116 1.00 58.79  ? 141 ALA A O   1 
ATOM   931   C CB  . ALA A 1 118 ? 118.541 141.632 161.221 1.00 58.79  ? 141 ALA A CB  1 
ATOM   932   N N   . ARG A 1 119 ? 117.752 142.758 158.310 1.00 59.65  ? 142 ARG A N   1 
ATOM   933   C CA  . ARG A 1 119 ? 116.862 143.539 157.458 1.00 59.65  ? 142 ARG A CA  1 
ATOM   934   C C   . ARG A 1 119 ? 116.292 142.698 156.324 1.00 59.65  ? 142 ARG A C   1 
ATOM   935   O O   . ARG A 1 119 ? 115.154 142.924 155.898 1.00 59.65  ? 142 ARG A O   1 
ATOM   936   C CB  . ARG A 1 119 ? 117.599 144.754 156.896 1.00 59.65  ? 142 ARG A CB  1 
ATOM   937   C CG  . ARG A 1 119 ? 116.702 145.744 156.169 1.00 59.65  ? 142 ARG A CG  1 
ATOM   938   C CD  . ARG A 1 119 ? 117.517 146.782 155.416 1.00 59.65  ? 142 ARG A CD  1 
ATOM   939   N NE  . ARG A 1 119 ? 118.225 146.202 154.278 1.00 59.65  ? 142 ARG A NE  1 
ATOM   940   C CZ  . ARG A 1 119 ? 118.970 146.900 153.428 1.00 59.65  ? 142 ARG A CZ  1 
ATOM   941   N NH1 . ARG A 1 119 ? 119.108 148.209 153.584 1.00 59.65  ? 142 ARG A NH1 1 
ATOM   942   N NH2 . ARG A 1 119 ? 119.579 146.289 152.420 1.00 59.65  ? 142 ARG A NH2 1 
ATOM   943   N N   . LEU A 1 120 ? 117.062 141.727 155.827 1.00 55.39  ? 143 LEU A N   1 
ATOM   944   C CA  . LEU A 1 120 ? 116.580 140.894 154.730 1.00 55.39  ? 143 LEU A CA  1 
ATOM   945   C C   . LEU A 1 120 ? 115.442 139.981 155.168 1.00 55.39  ? 143 LEU A C   1 
ATOM   946   O O   . LEU A 1 120 ? 114.586 139.625 154.350 1.00 55.39  ? 143 LEU A O   1 
ATOM   947   C CB  . LEU A 1 120 ? 117.731 140.069 154.154 1.00 55.39  ? 143 LEU A CB  1 
ATOM   948   C CG  . LEU A 1 120 ? 117.471 139.392 152.809 1.00 55.39  ? 143 LEU A CG  1 
ATOM   949   C CD1 . LEU A 1 120 ? 117.053 140.418 151.771 1.00 55.39  ? 143 LEU A CD1 1 
ATOM   950   C CD2 . LEU A 1 120 ? 118.703 138.632 152.350 1.00 55.39  ? 143 LEU A CD2 1 
ATOM   951   N N   . LEU A 1 121 ? 115.410 139.594 156.441 1.00 67.16  ? 144 LEU A N   1 
ATOM   952   C CA  . LEU A 1 121 ? 114.362 138.731 156.970 1.00 67.16  ? 144 LEU A CA  1 
ATOM   953   C C   . LEU A 1 121 ? 113.148 139.508 157.464 1.00 67.16  ? 144 LEU A C   1 
ATOM   954   O O   . LEU A 1 121 ? 112.294 138.927 158.142 1.00 67.16  ? 144 LEU A O   1 
ATOM   955   C CB  . LEU A 1 121 ? 114.914 137.864 158.105 1.00 67.16  ? 144 LEU A CB  1 
ATOM   956   C CG  . LEU A 1 121 ? 115.970 136.827 157.721 1.00 67.16  ? 144 LEU A CG  1 
ATOM   957   C CD1 . LEU A 1 121 ? 116.378 136.007 158.934 1.00 67.16  ? 144 LEU A CD1 1 
ATOM   958   C CD2 . LEU A 1 121 ? 115.457 135.928 156.609 1.00 67.16  ? 144 LEU A CD2 1 
ATOM   959   N N   . ASN A 1 122 ? 113.058 140.801 157.144 1.00 77.13  ? 145 ASN A N   1 
ATOM   960   C CA  . ASN A 1 122 ? 111.931 141.647 157.548 1.00 77.13  ? 145 ASN A CA  1 
ATOM   961   C C   . ASN A 1 122 ? 111.776 141.684 159.067 1.00 77.13  ? 145 ASN A C   1 
ATOM   962   O O   . ASN A 1 122 ? 110.663 141.701 159.596 1.00 77.13  ? 145 ASN A O   1 
ATOM   963   C CB  . ASN A 1 122 ? 110.631 141.194 156.879 1.00 77.13  ? 145 ASN A CB  1 
ATOM   964   C CG  . ASN A 1 122 ? 110.774 141.031 155.380 1.00 77.13  ? 145 ASN A CG  1 
ATOM   965   O OD1 . ASN A 1 122 ? 111.592 141.697 154.747 1.00 77.13  ? 145 ASN A OD1 1 
ATOM   966   N ND2 . ASN A 1 122 ? 109.976 140.139 154.803 1.00 77.13  ? 145 ASN A ND2 1 
ATOM   967   N N   . HIS A 1 123 ? 112.903 141.697 159.774 1.00 82.44  ? 146 HIS A N   1 
ATOM   968   C CA  . HIS A 1 123 ? 112.923 141.755 161.228 1.00 82.44  ? 146 HIS A CA  1 
ATOM   969   C C   . HIS A 1 123 ? 113.569 143.056 161.681 1.00 82.44  ? 146 HIS A C   1 
ATOM   970   O O   . HIS A 1 123 ? 114.563 143.503 161.099 1.00 82.44  ? 146 HIS A O   1 
ATOM   971   C CB  . HIS A 1 123 ? 113.679 140.563 161.822 1.00 82.44  ? 146 HIS A CB  1 
ATOM   972   C CG  . HIS A 1 123 ? 113.830 140.625 163.310 1.00 82.44  ? 146 HIS A CG  1 
ATOM   973   N ND1 . HIS A 1 123 ? 112.752 140.701 164.165 1.00 82.44  ? 146 HIS A ND1 1 
ATOM   974   C CD2 . HIS A 1 123 ? 114.934 140.626 164.094 1.00 82.44  ? 146 HIS A CD2 1 
ATOM   975   C CE1 . HIS A 1 123 ? 113.185 140.744 165.413 1.00 82.44  ? 146 HIS A CE1 1 
ATOM   976   N NE2 . HIS A 1 123 ? 114.505 140.700 165.397 1.00 82.44  ? 146 HIS A NE2 1 
ATOM   977   N N   . SER A 1 124 ? 113.001 143.659 162.721 1.00 87.82  ? 147 SER A N   1 
ATOM   978   C CA  . SER A 1 124 ? 113.490 144.920 163.265 1.00 87.82  ? 147 SER A CA  1 
ATOM   979   C C   . SER A 1 124 ? 114.356 144.636 164.485 1.00 87.82  ? 147 SER A C   1 
ATOM   980   O O   . SER A 1 124 ? 113.892 144.022 165.452 1.00 87.82  ? 147 SER A O   1 
ATOM   981   C CB  . SER A 1 124 ? 112.327 145.840 163.633 1.00 87.82  ? 147 SER A CB  1 
ATOM   982   O OG  . SER A 1 124 ? 111.314 145.129 164.323 1.00 87.82  ? 147 SER A OG  1 
ATOM   983   N N   . LEU A 1 125 ? 115.609 145.081 164.436 1.00 93.83  ? 148 LEU A N   1 
ATOM   984   C CA  . LEU A 1 125 ? 116.519 144.877 165.552 1.00 93.83  ? 148 LEU A CA  1 
ATOM   985   C C   . LEU A 1 125 ? 116.159 145.797 166.715 1.00 93.83  ? 148 LEU A C   1 
ATOM   986   O O   . LEU A 1 125 ? 115.533 146.847 166.547 1.00 93.83  ? 148 LEU A O   1 
ATOM   987   C CB  . LEU A 1 125 ? 117.964 145.123 165.118 1.00 93.83  ? 148 LEU A CB  1 
ATOM   988   C CG  . LEU A 1 125 ? 118.581 144.082 164.185 1.00 93.83  ? 148 LEU A CG  1 
ATOM   989   C CD1 . LEU A 1 125 ? 120.009 144.463 163.833 1.00 93.83  ? 148 LEU A CD1 1 
ATOM   990   C CD2 . LEU A 1 125 ? 118.533 142.701 164.818 1.00 93.83  ? 148 LEU A CD2 1 
ATOM   991   N N   . GLU A 1 126 ? 116.568 145.386 167.913 1.00 120.81 ? 149 GLU A N   1 
ATOM   992   C CA  . GLU A 1 126 ? 116.314 146.169 169.113 1.00 120.81 ? 149 GLU A CA  1 
ATOM   993   C C   . GLU A 1 126 ? 117.289 147.336 169.190 1.00 120.81 ? 149 GLU A C   1 
ATOM   994   O O   . GLU A 1 126 ? 118.508 147.144 169.142 1.00 120.81 ? 149 GLU A O   1 
ATOM   995   C CB  . GLU A 1 126 ? 116.435 145.291 170.358 1.00 120.81 ? 149 GLU A CB  1 
ATOM   996   C CG  . GLU A 1 126 ? 115.635 143.998 170.293 1.00 120.81 ? 149 GLU A CG  1 
ATOM   997   C CD  . GLU A 1 126 ? 114.140 144.234 170.189 1.00 120.81 ? 149 GLU A CD  1 
ATOM   998   O OE1 . GLU A 1 126 ? 113.636 144.394 169.057 1.00 120.81 ? 149 GLU A OE1 1 
ATOM   999   O OE2 . GLU A 1 126 ? 113.468 144.260 171.242 1.00 120.81 ? 149 GLU A OE2 1 
ATOM   1000  N N   . ILE A 1 127 ? 116.752 148.541 169.309 1.00 146.89 ? 150 ILE A N   1 
ATOM   1001  C CA  . ILE A 1 127 ? 117.538 149.771 169.368 1.00 146.89 ? 150 ILE A CA  1 
ATOM   1002  C C   . ILE A 1 127 ? 117.513 150.280 170.802 1.00 146.89 ? 150 ILE A C   1 
ATOM   1003  O O   . ILE A 1 127 ? 116.426 150.474 171.358 1.00 146.89 ? 150 ILE A O   1 
ATOM   1004  C CB  . ILE A 1 127 ? 117.000 150.844 168.402 1.00 146.89 ? 150 ILE A CB  1 
ATOM   1005  C CG1 . ILE A 1 127 ? 116.652 150.226 167.046 1.00 146.89 ? 150 ILE A CG1 1 
ATOM   1006  C CG2 . ILE A 1 127 ? 118.012 151.967 168.234 1.00 146.89 ? 150 ILE A CG2 1 
ATOM   1007  C CD1 . ILE A 1 127 ? 117.812 149.519 166.374 1.00 146.89 ? 150 ILE A CD1 1 
ATOM   1008  N N   . PRO A 1 128 ? 118.673 150.509 171.436 1.00 161.15 ? 151 PRO A N   1 
ATOM   1009  C CA  . PRO A 1 128 ? 118.739 151.003 172.815 1.00 161.15 ? 151 PRO A CA  1 
ATOM   1010  C C   . PRO A 1 128 ? 118.315 152.463 172.936 1.00 161.15 ? 151 PRO A C   1 
ATOM   1011  O O   . PRO A 1 128 ? 118.890 153.186 173.750 1.00 161.15 ? 151 PRO A O   1 
ATOM   1012  C CB  . PRO A 1 128 ? 120.217 150.835 173.174 1.00 161.15 ? 151 PRO A CB  1 
ATOM   1013  C CG  . PRO A 1 128 ? 120.926 150.931 171.870 1.00 161.15 ? 151 PRO A CG  1 
ATOM   1014  C CD  . PRO A 1 128 ? 120.012 150.296 170.860 1.00 161.15 ? 151 PRO A CD  1 
ATOM   1015  N N   . ARG A 1 139 ? 133.062 155.490 184.640 1.00 179.47 ? 162 ARG A N   1 
ATOM   1016  C CA  . ARG A 1 139 ? 133.952 155.875 183.551 1.00 179.47 ? 162 ARG A CA  1 
ATOM   1017  C C   . ARG A 1 139 ? 135.143 156.670 184.075 1.00 179.47 ? 162 ARG A C   1 
ATOM   1018  O O   . ARG A 1 139 ? 135.032 157.865 184.351 1.00 179.47 ? 162 ARG A O   1 
ATOM   1019  C CB  . ARG A 1 139 ? 133.194 156.691 182.502 1.00 179.47 ? 162 ARG A CB  1 
ATOM   1020  C CG  . ARG A 1 139 ? 134.038 157.109 181.309 1.00 179.47 ? 162 ARG A CG  1 
ATOM   1021  C CD  . ARG A 1 139 ? 133.230 157.936 180.324 1.00 179.47 ? 162 ARG A CD  1 
ATOM   1022  N NE  . ARG A 1 139 ? 134.029 158.355 179.177 1.00 179.47 ? 162 ARG A NE  1 
ATOM   1023  C CZ  . ARG A 1 139 ? 133.561 159.078 178.164 1.00 179.47 ? 162 ARG A CZ  1 
ATOM   1024  N NH1 . ARG A 1 139 ? 132.293 159.465 178.154 1.00 179.47 ? 162 ARG A NH1 1 
ATOM   1025  N NH2 . ARG A 1 139 ? 134.360 159.414 177.162 1.00 179.47 ? 162 ARG A NH2 1 
ATOM   1026  N N   . SER A 1 140 ? 136.284 155.998 184.212 1.00 143.78 ? 163 SER A N   1 
ATOM   1027  C CA  . SER A 1 140 ? 137.508 156.616 184.701 1.00 143.78 ? 163 SER A CA  1 
ATOM   1028  C C   . SER A 1 140 ? 138.670 156.181 183.823 1.00 143.78 ? 163 SER A C   1 
ATOM   1029  O O   . SER A 1 140 ? 138.879 154.982 183.613 1.00 143.78 ? 163 SER A O   1 
ATOM   1030  C CB  . SER A 1 140 ? 137.775 156.240 186.162 1.00 143.78 ? 163 SER A CB  1 
ATOM   1031  O OG  . SER A 1 140 ? 138.440 154.992 186.254 1.00 143.78 ? 163 SER A OG  1 
ATOM   1032  N N   . THR A 1 141 ? 139.423 157.158 183.311 1.00 114.77 ? 164 THR A N   1 
ATOM   1033  C CA  . THR A 1 141 ? 140.561 156.839 182.456 1.00 114.77 ? 164 THR A CA  1 
ATOM   1034  C C   . THR A 1 141 ? 141.722 156.276 183.267 1.00 114.77 ? 164 THR A C   1 
ATOM   1035  O O   . THR A 1 141 ? 142.356 155.297 182.857 1.00 114.77 ? 164 THR A O   1 
ATOM   1036  C CB  . THR A 1 141 ? 141.000 158.082 181.681 1.00 114.77 ? 164 THR A CB  1 
ATOM   1037  O OG1 . THR A 1 141 ? 139.926 158.529 180.845 1.00 114.77 ? 164 THR A OG1 1 
ATOM   1038  C CG2 . THR A 1 141 ? 142.209 157.770 180.815 1.00 114.77 ? 164 THR A CG2 1 
ATOM   1039  N N   . THR A 1 142 ? 142.013 156.876 184.418 1.00 109.95 ? 165 THR A N   1 
ATOM   1040  C CA  . THR A 1 142 ? 143.104 156.402 185.255 1.00 109.95 ? 165 THR A CA  1 
ATOM   1041  C C   . THR A 1 142 ? 142.771 155.041 185.856 1.00 109.95 ? 165 THR A C   1 
ATOM   1042  O O   . THR A 1 142 ? 141.604 154.686 186.047 1.00 109.95 ? 165 THR A O   1 
ATOM   1043  C CB  . THR A 1 142 ? 143.401 157.406 186.370 1.00 109.95 ? 165 THR A CB  1 
ATOM   1044  O OG1 . THR A 1 142 ? 144.410 156.875 187.238 1.00 109.95 ? 165 THR A OG1 1 
ATOM   1045  C CG2 . THR A 1 142 ? 142.145 157.696 187.177 1.00 109.95 ? 165 THR A CG2 1 
ATOM   1046  N N   . THR A 1 143 ? 143.818 154.271 186.153 1.00 78.46  ? 166 THR A N   1 
ATOM   1047  C CA  . THR A 1 143 ? 143.672 152.931 186.700 1.00 78.46  ? 166 THR A CA  1 
ATOM   1048  C C   . THR A 1 143 ? 144.453 152.836 188.005 1.00 78.46  ? 166 THR A C   1 
ATOM   1049  O O   . THR A 1 143 ? 145.659 153.137 188.028 1.00 78.46  ? 166 THR A O   1 
ATOM   1050  C CB  . THR A 1 143 ? 144.164 151.870 185.707 1.00 78.46  ? 166 THR A CB  1 
ATOM   1051  O OG1 . THR A 1 143 ? 145.492 152.195 185.276 1.00 78.46  ? 166 THR A OG1 1 
ATOM   1052  C CG2 . THR A 1 143 ? 143.246 151.805 184.498 1.00 78.46  ? 166 THR A CG2 1 
ATOM   1053  N N   . PRO A 1 144 ? 143.813 152.433 189.106 1.00 73.43  ? 167 PRO A N   1 
ATOM   1054  C CA  . PRO A 1 144 ? 144.567 152.281 190.364 1.00 73.43  ? 167 PRO A CA  1 
ATOM   1055  C C   . PRO A 1 144 ? 145.629 151.198 190.292 1.00 73.43  ? 167 PRO A C   1 
ATOM   1056  O O   . PRO A 1 144 ? 146.793 151.448 190.632 1.00 73.43  ? 167 PRO A O   1 
ATOM   1057  C CB  . PRO A 1 144 ? 143.470 151.951 191.388 1.00 73.43  ? 167 PRO A CB  1 
ATOM   1058  C CG  . PRO A 1 144 ? 142.190 152.410 190.756 1.00 73.43  ? 167 PRO A CG  1 
ATOM   1059  C CD  . PRO A 1 144 ? 142.373 152.195 189.289 1.00 73.43  ? 167 PRO A CD  1 
ATOM   1060  N N   . ASP A 1 145 ? 145.261 149.996 189.857 1.00 57.08  ? 168 ASP A N   1 
ATOM   1061  C CA  . ASP A 1 145 ? 146.193 148.890 189.717 1.00 57.08  ? 168 ASP A CA  1 
ATOM   1062  C C   . ASP A 1 145 ? 146.282 148.472 188.255 1.00 57.08  ? 168 ASP A C   1 
ATOM   1063  O O   . ASP A 1 145 ? 145.371 148.715 187.459 1.00 57.08  ? 168 ASP A O   1 
ATOM   1064  C CB  . ASP A 1 145 ? 145.775 147.694 190.582 1.00 57.08  ? 168 ASP A CB  1 
ATOM   1065  C CG  . ASP A 1 145 ? 146.909 146.712 190.804 1.00 57.08  ? 168 ASP A CG  1 
ATOM   1066  O OD1 . ASP A 1 145 ? 147.743 146.958 191.699 1.00 57.08  ? 168 ASP A OD1 1 
ATOM   1067  O OD2 . ASP A 1 145 ? 146.968 145.696 190.080 1.00 57.08  ? 168 ASP A OD2 1 
ATOM   1068  N N   . VAL A 1 146 ? 147.399 147.834 187.909 1.00 44.63  ? 169 VAL A N   1 
ATOM   1069  C CA  . VAL A 1 146 ? 147.636 147.388 186.548 1.00 44.63  ? 169 VAL A CA  1 
ATOM   1070  C C   . VAL A 1 146 ? 147.520 145.874 186.400 1.00 44.63  ? 169 VAL A C   1 
ATOM   1071  O O   . VAL A 1 146 ? 147.078 145.401 185.346 1.00 44.63  ? 169 VAL A O   1 
ATOM   1072  C CB  . VAL A 1 146 ? 149.009 147.881 186.048 1.00 44.63  ? 169 VAL A CB  1 
ATOM   1073  C CG1 . VAL A 1 146 ? 149.145 147.662 184.550 1.00 44.63  ? 169 VAL A CG1 1 
ATOM   1074  C CG2 . VAL A 1 146 ? 149.199 149.348 186.392 1.00 44.63  ? 169 VAL A CG2 1 
ATOM   1075  N N   . PHE A 1 147 ? 147.898 145.101 187.420 1.00 40.60  ? 170 PHE A N   1 
ATOM   1076  C CA  . PHE A 1 147 ? 147.823 143.646 187.322 1.00 40.60  ? 170 PHE A CA  1 
ATOM   1077  C C   . PHE A 1 147 ? 146.381 143.178 187.165 1.00 40.60  ? 170 PHE A C   1 
ATOM   1078  O O   . PHE A 1 147 ? 146.079 142.318 186.325 1.00 40.60  ? 170 PHE A O   1 
ATOM   1079  C CB  . PHE A 1 147 ? 148.470 143.011 188.553 1.00 40.60  ? 170 PHE A CB  1 
ATOM   1080  C CG  . PHE A 1 147 ? 148.977 141.618 188.323 1.00 40.60  ? 170 PHE A CG  1 
ATOM   1081  C CD1 . PHE A 1 147 ? 148.336 140.531 188.892 1.00 40.60  ? 170 PHE A CD1 1 
ATOM   1082  C CD2 . PHE A 1 147 ? 150.094 141.395 187.537 1.00 40.60  ? 170 PHE A CD2 1 
ATOM   1083  C CE1 . PHE A 1 147 ? 148.801 139.248 188.682 1.00 40.60  ? 170 PHE A CE1 1 
ATOM   1084  C CE2 . PHE A 1 147 ? 150.563 140.115 187.323 1.00 40.60  ? 170 PHE A CE2 1 
ATOM   1085  C CZ  . PHE A 1 147 ? 149.915 139.040 187.897 1.00 40.60  ? 170 PHE A CZ  1 
ATOM   1086  N N   . ASN A 1 148 ? 145.472 143.732 187.971 1.00 41.55  ? 171 ASN A N   1 
ATOM   1087  C CA  . ASN A 1 148 ? 144.066 143.361 187.864 1.00 41.55  ? 171 ASN A CA  1 
ATOM   1088  C C   . ASN A 1 148 ? 143.496 143.753 186.508 1.00 41.55  ? 171 ASN A C   1 
ATOM   1089  O O   . ASN A 1 148 ? 142.691 143.016 185.928 1.00 41.55  ? 171 ASN A O   1 
ATOM   1090  C CB  . ASN A 1 148 ? 143.263 144.009 188.991 1.00 41.55  ? 171 ASN A CB  1 
ATOM   1091  C CG  . ASN A 1 148 ? 143.732 143.573 190.364 1.00 41.55  ? 171 ASN A CG  1 
ATOM   1092  O OD1 . ASN A 1 148 ? 144.290 142.488 190.526 1.00 41.55  ? 171 ASN A OD1 1 
ATOM   1093  N ND2 . ASN A 1 148 ? 143.507 144.418 191.362 1.00 41.55  ? 171 ASN A ND2 1 
ATOM   1094  N N   . THR A 1 149 ? 143.911 144.908 185.981 1.00 40.10  ? 172 THR A N   1 
ATOM   1095  C CA  . THR A 1 149 ? 143.449 145.326 184.661 1.00 40.10  ? 172 THR A CA  1 
ATOM   1096  C C   . THR A 1 149 ? 143.941 144.371 183.581 1.00 40.10  ? 172 THR A C   1 
ATOM   1097  O O   . THR A 1 149 ? 143.186 144.008 182.670 1.00 40.10  ? 172 THR A O   1 
ATOM   1098  C CB  . THR A 1 149 ? 143.914 146.752 184.370 1.00 40.10  ? 172 THR A CB  1 
ATOM   1099  O OG1 . THR A 1 149 ? 143.445 147.628 185.402 1.00 40.10  ? 172 THR A OG1 1 
ATOM   1100  C CG2 . THR A 1 149 ? 143.375 147.225 183.030 1.00 40.10  ? 172 THR A CG2 1 
ATOM   1101  N N   . LYS A 1 150 ? 145.206 143.952 183.668 1.00 34.03  ? 173 LYS A N   1 
ATOM   1102  C CA  . LYS A 1 150 ? 145.739 142.988 182.711 1.00 34.03  ? 173 LYS A CA  1 
ATOM   1103  C C   . LYS A 1 150 ? 144.966 141.677 182.770 1.00 34.03  ? 173 LYS A C   1 
ATOM   1104  O O   . LYS A 1 150 ? 144.601 141.109 181.733 1.00 34.03  ? 173 LYS A O   1 
ATOM   1105  C CB  . LYS A 1 150 ? 147.223 142.743 182.984 1.00 34.03  ? 173 LYS A CB  1 
ATOM   1106  C CG  . LYS A 1 150 ? 148.129 143.917 182.668 1.00 34.03  ? 173 LYS A CG  1 
ATOM   1107  C CD  . LYS A 1 150 ? 149.573 143.588 183.010 1.00 34.03  ? 173 LYS A CD  1 
ATOM   1108  C CE  . LYS A 1 150 ? 150.508 144.724 182.642 1.00 34.03  ? 173 LYS A CE  1 
ATOM   1109  N NZ  . LYS A 1 150 ? 151.924 144.392 182.956 1.00 34.03  ? 173 LYS A NZ  1 
ATOM   1110  N N   . ILE A 1 151 ? 144.706 141.183 183.983 1.00 42.80  ? 174 ILE A N   1 
ATOM   1111  C CA  . ILE A 1 151 ? 143.986 139.919 184.132 1.00 42.80  ? 174 ILE A CA  1 
ATOM   1112  C C   . ILE A 1 151 ? 142.572 140.038 183.573 1.00 42.80  ? 174 ILE A C   1 
ATOM   1113  O O   . ILE A 1 151 ? 142.082 139.135 182.881 1.00 42.80  ? 174 ILE A O   1 
ATOM   1114  C CB  . ILE A 1 151 ? 143.979 139.479 185.607 1.00 42.80  ? 174 ILE A CB  1 
ATOM   1115  C CG1 . ILE A 1 151 ? 145.405 139.207 186.088 1.00 42.80  ? 174 ILE A CG1 1 
ATOM   1116  C CG2 . ILE A 1 151 ? 143.111 138.246 185.795 1.00 42.80  ? 174 ILE A CG2 1 
ATOM   1117  C CD1 . ILE A 1 151 ? 146.144 138.184 185.258 1.00 42.80  ? 174 ILE A CD1 1 
ATOM   1118  N N   . GLY A 1 152 ? 141.896 141.153 183.861 1.00 65.79  ? 175 GLY A N   1 
ATOM   1119  C CA  . GLY A 1 152 ? 140.550 141.344 183.348 1.00 65.79  ? 175 GLY A CA  1 
ATOM   1120  C C   . GLY A 1 152 ? 140.506 141.420 181.835 1.00 65.79  ? 175 GLY A C   1 
ATOM   1121  O O   . GLY A 1 152 ? 139.632 140.826 181.200 1.00 65.79  ? 175 GLY A O   1 
ATOM   1122  N N   . SER A 1 153 ? 141.450 142.151 181.236 1.00 43.09  ? 176 SER A N   1 
ATOM   1123  C CA  . SER A 1 153 ? 141.501 142.235 179.780 1.00 43.09  ? 176 SER A CA  1 
ATOM   1124  C C   . SER A 1 153 ? 141.787 140.873 179.160 1.00 43.09  ? 176 SER A C   1 
ATOM   1125  O O   . SER A 1 153 ? 141.196 140.512 178.135 1.00 43.09  ? 176 SER A O   1 
ATOM   1126  C CB  . SER A 1 153 ? 142.555 143.255 179.353 1.00 43.09  ? 176 SER A CB  1 
ATOM   1127  O OG  . SER A 1 153 ? 143.850 142.838 179.747 1.00 43.09  ? 176 SER A OG  1 
ATOM   1128  N N   . CYS A 1 154 ? 142.688 140.102 179.771 1.00 47.35  ? 177 CYS A N   1 
ATOM   1129  C CA  . CYS A 1 154 ? 142.987 138.761 179.277 1.00 47.35  ? 177 CYS A CA  1 
ATOM   1130  C C   . CYS A 1 154 ? 141.748 137.874 179.313 1.00 47.35  ? 177 CYS A C   1 
ATOM   1131  O O   . CYS A 1 154 ? 141.429 137.184 178.333 1.00 47.35  ? 177 CYS A O   1 
ATOM   1132  C CB  . CYS A 1 154 ? 144.115 138.155 180.111 1.00 47.35  ? 177 CYS A CB  1 
ATOM   1133  S SG  . CYS A 1 154 ? 144.954 136.740 179.386 1.00 47.35  ? 177 CYS A SG  1 
ATOM   1134  N N   . GLY A 1 155 ? 141.035 137.881 180.441 1.00 59.00  ? 178 GLY A N   1 
ATOM   1135  C CA  . GLY A 1 155 ? 139.826 137.081 180.543 1.00 59.00  ? 178 GLY A CA  1 
ATOM   1136  C C   . GLY A 1 155 ? 138.755 137.514 179.560 1.00 59.00  ? 178 GLY A C   1 
ATOM   1137  O O   . GLY A 1 155 ? 138.060 136.679 178.974 1.00 59.00  ? 178 GLY A O   1 
ATOM   1138  N N   . PHE A 1 156 ? 138.614 138.827 179.358 1.00 48.70  ? 179 PHE A N   1 
ATOM   1139  C CA  . PHE A 1 156 ? 137.630 139.321 178.404 1.00 48.70  ? 179 PHE A CA  1 
ATOM   1140  C C   . PHE A 1 156 ? 137.975 138.890 176.985 1.00 48.70  ? 179 PHE A C   1 
ATOM   1141  O O   . PHE A 1 156 ? 137.089 138.504 176.216 1.00 48.70  ? 179 PHE A O   1 
ATOM   1142  C CB  . PHE A 1 156 ? 137.525 140.842 178.490 1.00 48.70  ? 179 PHE A CB  1 
ATOM   1143  C CG  . PHE A 1 156 ? 136.793 141.461 177.337 1.00 48.70  ? 179 PHE A CG  1 
ATOM   1144  C CD1 . PHE A 1 156 ? 137.475 142.185 176.374 1.00 48.70  ? 179 PHE A CD1 1 
ATOM   1145  C CD2 . PHE A 1 156 ? 135.424 141.309 177.210 1.00 48.70  ? 179 PHE A CD2 1 
ATOM   1146  C CE1 . PHE A 1 156 ? 136.803 142.751 175.309 1.00 48.70  ? 179 PHE A CE1 1 
ATOM   1147  C CE2 . PHE A 1 156 ? 134.746 141.873 176.148 1.00 48.70  ? 179 PHE A CE2 1 
ATOM   1148  C CZ  . PHE A 1 156 ? 135.437 142.594 175.195 1.00 48.70  ? 179 PHE A CZ  1 
ATOM   1149  N N   . LEU A 1 157 ? 139.259 138.942 176.621 1.00 40.30  ? 180 LEU A N   1 
ATOM   1150  C CA  . LEU A 1 157 ? 139.658 138.508 175.286 1.00 40.30  ? 180 LEU A CA  1 
ATOM   1151  C C   . LEU A 1 157 ? 139.419 137.014 175.096 1.00 40.30  ? 180 LEU A C   1 
ATOM   1152  O O   . LEU A 1 157 ? 138.971 136.581 174.026 1.00 40.30  ? 180 LEU A O   1 
ATOM   1153  C CB  . LEU A 1 157 ? 141.124 138.855 175.036 1.00 40.30  ? 180 LEU A CB  1 
ATOM   1154  C CG  . LEU A 1 157 ? 141.438 140.345 174.891 1.00 40.30  ? 180 LEU A CG  1 
ATOM   1155  C CD1 . LEU A 1 157 ? 142.910 140.560 174.586 1.00 40.30  ? 180 LEU A CD1 1 
ATOM   1156  C CD2 . LEU A 1 157 ? 140.568 140.971 173.815 1.00 40.30  ? 180 LEU A CD2 1 
ATOM   1157  N N   . TRP A 1 158 ? 139.701 136.212 176.126 1.00 52.06  ? 181 TRP A N   1 
ATOM   1158  C CA  . TRP A 1 158 ? 139.443 134.777 176.032 1.00 52.06  ? 181 TRP A CA  1 
ATOM   1159  C C   . TRP A 1 158 ? 137.955 134.500 175.847 1.00 52.06  ? 181 TRP A C   1 
ATOM   1160  O O   . TRP A 1 158 ? 137.557 133.700 174.986 1.00 52.06  ? 181 TRP A O   1 
ATOM   1161  C CB  . TRP A 1 158 ? 139.976 134.069 177.277 1.00 52.06  ? 181 TRP A CB  1 
ATOM   1162  C CG  . TRP A 1 158 ? 140.048 132.583 177.136 1.00 52.06  ? 181 TRP A CG  1 
ATOM   1163  C CD1 . TRP A 1 158 ? 140.850 131.879 176.288 1.00 52.06  ? 181 TRP A CD1 1 
ATOM   1164  C CD2 . TRP A 1 158 ? 139.290 131.614 177.869 1.00 52.06  ? 181 TRP A CD2 1 
ATOM   1165  N NE1 . TRP A 1 158 ? 140.638 130.531 176.445 1.00 52.06  ? 181 TRP A NE1 1 
ATOM   1166  C CE2 . TRP A 1 158 ? 139.684 130.342 177.411 1.00 52.06  ? 181 TRP A CE2 1 
ATOM   1167  C CE3 . TRP A 1 158 ? 138.316 131.698 178.868 1.00 52.06  ? 181 TRP A CE3 1 
ATOM   1168  C CZ2 . TRP A 1 158 ? 139.139 129.164 177.916 1.00 52.06  ? 181 TRP A CZ2 1 
ATOM   1169  C CZ3 . TRP A 1 158 ? 137.776 130.528 179.369 1.00 52.06  ? 181 TRP A CZ3 1 
ATOM   1170  C CH2 . TRP A 1 158 ? 138.188 129.278 178.892 1.00 52.06  ? 181 TRP A CH2 1 
ATOM   1171  N N   . GLY A 1 159 ? 137.114 135.157 176.650 1.00 92.30  ? 182 GLY A N   1 
ATOM   1172  C CA  . GLY A 1 159 ? 135.679 134.980 176.502 1.00 92.30  ? 182 GLY A CA  1 
ATOM   1173  C C   . GLY A 1 159 ? 135.173 135.435 175.147 1.00 92.30  ? 182 GLY A C   1 
ATOM   1174  O O   . GLY A 1 159 ? 134.281 134.813 174.565 1.00 92.30  ? 182 GLY A O   1 
ATOM   1175  N N   . TYR A 1 160 ? 135.748 136.517 174.618 1.00 55.31  ? 183 TYR A N   1 
ATOM   1176  C CA  . TYR A 1 160 ? 135.341 137.012 173.308 1.00 55.31  ? 183 TYR A CA  1 
ATOM   1177  C C   . TYR A 1 160 ? 135.707 136.026 172.207 1.00 55.31  ? 183 TYR A C   1 
ATOM   1178  O O   . TYR A 1 160 ? 134.915 135.795 171.285 1.00 55.31  ? 183 TYR A O   1 
ATOM   1179  C CB  . TYR A 1 160 ? 135.980 138.375 173.051 1.00 55.31  ? 183 TYR A CB  1 
ATOM   1180  C CG  . TYR A 1 160 ? 135.968 138.812 171.607 1.00 55.31  ? 183 TYR A CG  1 
ATOM   1181  C CD1 . TYR A 1 160 ? 134.781 139.147 170.973 1.00 55.31  ? 183 TYR A CD1 1 
ATOM   1182  C CD2 . TYR A 1 160 ? 137.147 138.902 170.880 1.00 55.31  ? 183 TYR A CD2 1 
ATOM   1183  C CE1 . TYR A 1 160 ? 134.766 139.553 169.654 1.00 55.31  ? 183 TYR A CE1 1 
ATOM   1184  C CE2 . TYR A 1 160 ? 137.143 139.307 169.561 1.00 55.31  ? 183 TYR A CE2 1 
ATOM   1185  C CZ  . TYR A 1 160 ? 135.950 139.631 168.953 1.00 55.31  ? 183 TYR A CZ  1 
ATOM   1186  O OH  . TYR A 1 160 ? 135.939 140.036 167.640 1.00 55.31  ? 183 TYR A OH  1 
ATOM   1187  N N   . HIS A 1 161 ? 136.897 135.428 172.288 1.00 92.30  ? 184 HIS A N   1 
ATOM   1188  C CA  . HIS A 1 161 ? 137.280 134.430 171.293 1.00 92.30  ? 184 HIS A CA  1 
ATOM   1189  C C   . HIS A 1 161 ? 136.380 133.201 171.371 1.00 92.30  ? 184 HIS A C   1 
ATOM   1190  O O   . HIS A 1 161 ? 135.968 132.655 170.337 1.00 92.30  ? 184 HIS A O   1 
ATOM   1191  C CB  . HIS A 1 161 ? 138.746 134.039 171.474 1.00 92.30  ? 184 HIS A CB  1 
ATOM   1192  C CG  . HIS A 1 161 ? 139.708 135.042 170.918 1.00 92.30  ? 184 HIS A CG  1 
ATOM   1193  N ND1 . HIS A 1 161 ? 139.688 135.439 169.599 1.00 92.30  ? 184 HIS A ND1 1 
ATOM   1194  C CD2 . HIS A 1 161 ? 140.717 135.729 171.503 1.00 92.30  ? 184 HIS A CD2 1 
ATOM   1195  C CE1 . HIS A 1 161 ? 140.644 136.328 169.395 1.00 92.30  ? 184 HIS A CE1 1 
ATOM   1196  N NE2 . HIS A 1 161 ? 141.283 136.521 170.534 1.00 92.30  ? 184 HIS A NE2 1 
ATOM   1197  N N   . ARG A 1 162 ? 136.055 132.756 172.588 1.00 53.82  ? 185 ARG A N   1 
ATOM   1198  C CA  . ARG A 1 162 ? 135.148 131.618 172.728 1.00 53.82  ? 185 ARG A CA  1 
ATOM   1199  C C   . ARG A 1 162 ? 133.768 131.939 172.161 1.00 53.82  ? 185 ARG A C   1 
ATOM   1200  O O   . ARG A 1 162 ? 133.151 131.100 171.491 1.00 53.82  ? 185 ARG A O   1 
ATOM   1201  C CB  . ARG A 1 162 ? 135.043 131.203 174.194 1.00 53.82  ? 185 ARG A CB  1 
ATOM   1202  C CG  . ARG A 1 162 ? 136.255 130.451 174.713 1.00 53.82  ? 185 ARG A CG  1 
ATOM   1203  C CD  . ARG A 1 162 ? 135.874 129.508 175.840 1.00 53.82  ? 185 ARG A CD  1 
ATOM   1204  N NE  . ARG A 1 162 ? 135.085 130.180 176.868 1.00 53.82  ? 185 ARG A NE  1 
ATOM   1205  C CZ  . ARG A 1 162 ? 134.568 129.571 177.930 1.00 53.82  ? 185 ARG A CZ  1 
ATOM   1206  N NH1 . ARG A 1 162 ? 134.757 128.270 178.107 1.00 53.82  ? 185 ARG A NH1 1 
ATOM   1207  N NH2 . ARG A 1 162 ? 133.862 130.261 178.815 1.00 53.82  ? 185 ARG A NH2 1 
ATOM   1208  N N   . PHE A 1 163 ? 133.272 133.152 172.415 1.00 47.39  ? 186 PHE A N   1 
ATOM   1209  C CA  . PHE A 1 163 ? 131.971 133.546 171.886 1.00 47.39  ? 186 PHE A CA  1 
ATOM   1210  C C   . PHE A 1 163 ? 131.990 133.609 170.364 1.00 47.39  ? 186 PHE A C   1 
ATOM   1211  O O   . PHE A 1 163 ? 131.017 133.216 169.711 1.00 47.39  ? 186 PHE A O   1 
ATOM   1212  C CB  . PHE A 1 163 ? 131.554 134.892 172.475 1.00 47.39  ? 186 PHE A CB  1 
ATOM   1213  C CG  . PHE A 1 163 ? 130.333 135.484 171.834 1.00 47.39  ? 186 PHE A CG  1 
ATOM   1214  C CD1 . PHE A 1 163 ? 130.442 136.553 170.961 1.00 47.39  ? 186 PHE A CD1 1 
ATOM   1215  C CD2 . PHE A 1 163 ? 129.076 134.974 172.106 1.00 47.39  ? 186 PHE A CD2 1 
ATOM   1216  C CE1 . PHE A 1 163 ? 129.321 137.099 170.371 1.00 47.39  ? 186 PHE A CE1 1 
ATOM   1217  C CE2 . PHE A 1 163 ? 127.951 135.517 171.519 1.00 47.39  ? 186 PHE A CE2 1 
ATOM   1218  C CZ  . PHE A 1 163 ? 128.074 136.582 170.652 1.00 47.39  ? 186 PHE A CZ  1 
ATOM   1219  N N   . MET A 1 164 ? 133.087 134.099 169.782 1.00 49.35  ? 187 MET A N   1 
ATOM   1220  C CA  . MET A 1 164 ? 133.187 134.138 168.326 1.00 49.35  ? 187 MET A CA  1 
ATOM   1221  C C   . MET A 1 164 ? 133.200 132.733 167.740 1.00 49.35  ? 187 MET A C   1 
ATOM   1222  O O   . MET A 1 164 ? 132.563 132.476 166.711 1.00 49.35  ? 187 MET A O   1 
ATOM   1223  C CB  . MET A 1 164 ? 134.435 134.910 167.901 1.00 49.35  ? 187 MET A CB  1 
ATOM   1224  C CG  . MET A 1 164 ? 134.320 136.412 168.079 1.00 49.35  ? 187 MET A CG  1 
ATOM   1225  S SD  . MET A 1 164 ? 132.817 137.091 167.350 1.00 49.35  ? 187 MET A SD  1 
ATOM   1226  C CE  . MET A 1 164 ? 133.023 136.616 165.636 1.00 49.35  ? 187 MET A CE  1 
ATOM   1227  N N   . GLY A 1 165 ? 133.918 131.809 168.381 1.00 56.21  ? 188 GLY A N   1 
ATOM   1228  C CA  . GLY A 1 165 ? 133.891 130.427 167.924 1.00 56.21  ? 188 GLY A CA  1 
ATOM   1229  C C   . GLY A 1 165 ? 132.503 129.818 167.994 1.00 56.21  ? 188 GLY A C   1 
ATOM   1230  O O   . GLY A 1 165 ? 132.068 129.120 167.070 1.00 56.21  ? 188 GLY A O   1 
ATOM   1231  N N   . SER A 1 166 ? 131.784 130.077 169.089 1.00 51.49  ? 189 SER A N   1 
ATOM   1232  C CA  . SER A 1 166 ? 130.424 129.561 169.218 1.00 51.49  ? 189 SER A CA  1 
ATOM   1233  C C   . SER A 1 166 ? 129.506 130.149 168.152 1.00 51.49  ? 189 SER A C   1 
ATOM   1234  O O   . SER A 1 166 ? 128.669 129.439 167.580 1.00 51.49  ? 189 SER A O   1 
ATOM   1235  C CB  . SER A 1 166 ? 129.883 129.855 170.616 1.00 51.49  ? 189 SER A CB  1 
ATOM   1236  O OG  . SER A 1 166 ? 128.765 129.037 170.911 1.00 51.49  ? 189 SER A OG  1 
ATOM   1237  N N   . VAL A 1 167 ? 129.649 131.445 167.870 1.00 48.56  ? 190 VAL A N   1 
ATOM   1238  C CA  . VAL A 1 167 ? 128.823 132.080 166.847 1.00 48.56  ? 190 VAL A CA  1 
ATOM   1239  C C   . VAL A 1 167 ? 129.138 131.500 165.474 1.00 48.56  ? 190 VAL A C   1 
ATOM   1240  O O   . VAL A 1 167 ? 128.240 131.300 164.646 1.00 48.56  ? 190 VAL A O   1 
ATOM   1241  C CB  . VAL A 1 167 ? 129.014 133.607 166.883 1.00 48.56  ? 190 VAL A CB  1 
ATOM   1242  C CG1 . VAL A 1 167 ? 128.484 134.246 165.615 1.00 48.56  ? 190 VAL A CG1 1 
ATOM   1243  C CG2 . VAL A 1 167 ? 128.316 134.191 168.096 1.00 48.56  ? 190 VAL A CG2 1 
ATOM   1244  N N   . GLY A 1 168 ? 130.414 131.212 165.211 1.00 55.92  ? 191 GLY A N   1 
ATOM   1245  C CA  . GLY A 1 168 ? 130.767 130.566 163.957 1.00 55.92  ? 191 GLY A CA  1 
ATOM   1246  C C   . GLY A 1 168 ? 130.158 129.184 163.824 1.00 55.92  ? 191 GLY A C   1 
ATOM   1247  O O   . GLY A 1 168 ? 129.664 128.810 162.755 1.00 55.92  ? 191 GLY A O   1 
ATOM   1248  N N   . ARG A 1 169 ? 130.173 128.408 164.910 1.00 63.31  ? 192 ARG A N   1 
ATOM   1249  C CA  . ARG A 1 169 ? 129.553 127.087 164.867 1.00 63.31  ? 192 ARG A CA  1 
ATOM   1250  C C   . ARG A 1 169 ? 128.047 127.189 164.651 1.00 63.31  ? 192 ARG A C   1 
ATOM   1251  O O   . ARG A 1 169 ? 127.458 126.374 163.930 1.00 63.31  ? 192 ARG A O   1 
ATOM   1252  C CB  . ARG A 1 169 ? 129.865 126.314 166.147 1.00 63.31  ? 192 ARG A CB  1 
ATOM   1253  C CG  . ARG A 1 169 ? 129.677 124.810 166.019 1.00 63.31  ? 192 ARG A CG  1 
ATOM   1254  C CD  . ARG A 1 169 ? 130.496 124.052 167.052 1.00 63.31  ? 192 ARG A CD  1 
ATOM   1255  N NE  . ARG A 1 169 ? 131.929 124.289 166.901 1.00 63.31  ? 192 ARG A NE  1 
ATOM   1256  C CZ  . ARG A 1 169 ? 132.648 125.058 167.711 1.00 63.31  ? 192 ARG A CZ  1 
ATOM   1257  N NH1 . ARG A 1 169 ? 133.947 125.218 167.497 1.00 63.31  ? 192 ARG A NH1 1 
ATOM   1258  N NH2 . ARG A 1 169 ? 132.070 125.668 168.737 1.00 63.31  ? 192 ARG A NH2 1 
ATOM   1259  N N   . VAL A 1 170 ? 127.408 128.192 165.257 1.00 57.27  ? 193 VAL A N   1 
ATOM   1260  C CA  . VAL A 1 170 ? 125.971 128.371 165.065 1.00 57.27  ? 193 VAL A CA  1 
ATOM   1261  C C   . VAL A 1 170 ? 125.670 128.782 163.627 1.00 57.27  ? 193 VAL A C   1 
ATOM   1262  O O   . VAL A 1 170 ? 124.680 128.337 163.036 1.00 57.27  ? 193 VAL A O   1 
ATOM   1263  C CB  . VAL A 1 170 ? 125.416 129.387 166.080 1.00 57.27  ? 193 VAL A CB  1 
ATOM   1264  C CG1 . VAL A 1 170 ? 123.975 129.740 165.748 1.00 57.27  ? 193 VAL A CG1 1 
ATOM   1265  C CG2 . VAL A 1 170 ? 125.510 128.828 167.489 1.00 57.27  ? 193 VAL A CG2 1 
ATOM   1266  N N   . PHE A 1 171 ? 126.518 129.630 163.039 1.00 61.24  ? 194 PHE A N   1 
ATOM   1267  C CA  . PHE A 1 171 ? 126.352 129.981 161.630 1.00 61.24  ? 194 PHE A CA  1 
ATOM   1268  C C   . PHE A 1 171 ? 126.514 128.761 160.735 1.00 61.24  ? 194 PHE A C   1 
ATOM   1269  O O   . PHE A 1 171 ? 125.792 128.608 159.743 1.00 61.24  ? 194 PHE A O   1 
ATOM   1270  C CB  . PHE A 1 171 ? 127.351 131.066 161.228 1.00 61.24  ? 194 PHE A CB  1 
ATOM   1271  C CG  . PHE A 1 171 ? 127.004 132.436 161.734 1.00 61.24  ? 194 PHE A CG  1 
ATOM   1272  C CD1 . PHE A 1 171 ? 125.730 132.719 162.195 1.00 61.24  ? 194 PHE A CD1 1 
ATOM   1273  C CD2 . PHE A 1 171 ? 127.952 133.445 161.739 1.00 61.24  ? 194 PHE A CD2 1 
ATOM   1274  C CE1 . PHE A 1 171 ? 125.411 133.981 162.655 1.00 61.24  ? 194 PHE A CE1 1 
ATOM   1275  C CE2 . PHE A 1 171 ? 127.639 134.708 162.199 1.00 61.24  ? 194 PHE A CE2 1 
ATOM   1276  C CZ  . PHE A 1 171 ? 126.367 134.976 162.659 1.00 61.24  ? 194 PHE A CZ  1 
ATOM   1277  N N   . ARG A 1 172 ? 127.464 127.884 161.064 1.00 74.98  ? 195 ARG A N   1 
ATOM   1278  C CA  . ARG A 1 172 ? 127.636 126.665 160.279 1.00 74.98  ? 195 ARG A CA  1 
ATOM   1279  C C   . ARG A 1 172 ? 126.412 125.764 160.390 1.00 74.98  ? 195 ARG A C   1 
ATOM   1280  O O   . ARG A 1 172 ? 125.971 125.177 159.395 1.00 74.98  ? 195 ARG A O   1 
ATOM   1281  C CB  . ARG A 1 172 ? 128.895 125.922 160.724 1.00 74.98  ? 195 ARG A CB  1 
ATOM   1282  C CG  . ARG A 1 172 ? 129.426 124.940 159.695 1.00 74.98  ? 195 ARG A CG  1 
ATOM   1283  C CD  . ARG A 1 172 ? 130.760 124.356 160.126 1.00 74.98  ? 195 ARG A CD  1 
ATOM   1284  N NE  . ARG A 1 172 ? 131.611 125.357 160.765 1.00 74.98  ? 195 ARG A NE  1 
ATOM   1285  C CZ  . ARG A 1 172 ? 132.353 126.240 160.104 1.00 74.98  ? 195 ARG A CZ  1 
ATOM   1286  N NH1 . ARG A 1 172 ? 133.096 127.113 160.771 1.00 74.98  ? 195 ARG A NH1 1 
ATOM   1287  N NH2 . ARG A 1 172 ? 132.353 126.252 158.778 1.00 74.98  ? 195 ARG A NH2 1 
ATOM   1288  N N   . GLU A 1 173 ? 125.848 125.647 161.594 1.00 83.42  ? 196 GLU A N   1 
ATOM   1289  C CA  . GLU A 1 173 ? 124.627 124.863 161.764 1.00 83.42  ? 196 GLU A CA  1 
ATOM   1290  C C   . GLU A 1 173 ? 123.466 125.475 160.987 1.00 83.42  ? 196 GLU A C   1 
ATOM   1291  O O   . GLU A 1 173 ? 122.648 124.754 160.403 1.00 83.42  ? 196 GLU A O   1 
ATOM   1292  C CB  . GLU A 1 173 ? 124.279 124.747 163.248 1.00 83.42  ? 196 GLU A CB  1 
ATOM   1293  C CG  . GLU A 1 173 ? 125.274 123.933 164.056 1.00 83.42  ? 196 GLU A CG  1 
ATOM   1294  C CD  . GLU A 1 173 ? 125.175 122.447 163.776 1.00 83.42  ? 196 GLU A CD  1 
ATOM   1295  O OE1 . GLU A 1 173 ? 124.102 121.996 163.323 1.00 83.42  ? 196 GLU A OE1 1 
ATOM   1296  O OE2 . GLU A 1 173 ? 126.170 121.730 164.009 1.00 83.42  ? 196 GLU A OE2 1 
ATOM   1297  N N   . TRP A 1 174 ? 123.381 126.807 160.968 1.00 75.17  ? 197 TRP A N   1 
ATOM   1298  C CA  . TRP A 1 174 ? 122.334 127.479 160.206 1.00 75.17  ? 197 TRP A CA  1 
ATOM   1299  C C   . TRP A 1 174 ? 122.490 127.221 158.713 1.00 75.17  ? 197 TRP A C   1 
ATOM   1300  O O   . TRP A 1 174 ? 121.503 126.984 158.008 1.00 75.17  ? 197 TRP A O   1 
ATOM   1301  C CB  . TRP A 1 174 ? 122.363 128.980 160.500 1.00 75.17  ? 197 TRP A CB  1 
ATOM   1302  C CG  . TRP A 1 174 ? 121.145 129.733 160.051 1.00 75.17  ? 197 TRP A CG  1 
ATOM   1303  C CD1 . TRP A 1 174 ? 120.061 129.231 159.392 1.00 75.17  ? 197 TRP A CD1 1 
ATOM   1304  C CD2 . TRP A 1 174 ? 120.892 131.131 160.231 1.00 75.17  ? 197 TRP A CD2 1 
ATOM   1305  N NE1 . TRP A 1 174 ? 119.150 130.230 159.150 1.00 75.17  ? 197 TRP A NE1 1 
ATOM   1306  C CE2 . TRP A 1 174 ? 119.636 131.406 159.656 1.00 75.17  ? 197 TRP A CE2 1 
ATOM   1307  C CE3 . TRP A 1 174 ? 121.606 132.177 160.824 1.00 75.17  ? 197 TRP A CE3 1 
ATOM   1308  C CZ2 . TRP A 1 174 ? 119.079 132.682 159.656 1.00 75.17  ? 197 TRP A CZ2 1 
ATOM   1309  C CZ3 . TRP A 1 174 ? 121.051 133.443 160.822 1.00 75.17  ? 197 TRP A CZ3 1 
ATOM   1310  C CH2 . TRP A 1 174 ? 119.800 133.685 160.243 1.00 75.17  ? 197 TRP A CH2 1 
ATOM   1311  N N   . ASP A 1 175 ? 123.726 127.274 158.212 1.00 98.82  ? 198 ASP A N   1 
ATOM   1312  C CA  . ASP A 1 175 ? 123.966 126.983 156.803 1.00 98.82  ? 198 ASP A CA  1 
ATOM   1313  C C   . ASP A 1 175 ? 123.660 125.528 156.473 1.00 98.82  ? 198 ASP A C   1 
ATOM   1314  O O   . ASP A 1 175 ? 123.180 125.230 155.373 1.00 98.82  ? 198 ASP A O   1 
ATOM   1315  C CB  . ASP A 1 175 ? 125.411 127.320 156.433 1.00 98.82  ? 198 ASP A CB  1 
ATOM   1316  C CG  . ASP A 1 175 ? 125.747 126.952 155.002 1.00 98.82  ? 198 ASP A CG  1 
ATOM   1317  O OD1 . ASP A 1 175 ? 125.202 127.594 154.079 1.00 98.82  ? 198 ASP A OD1 1 
ATOM   1318  O OD2 . ASP A 1 175 ? 126.555 126.022 154.799 1.00 98.82  ? 198 ASP A OD2 1 
ATOM   1319  N N   . ASP A 1 176 ? 123.932 124.613 157.407 1.00 122.86 ? 199 ASP A N   1 
ATOM   1320  C CA  . ASP A 1 176 ? 123.598 123.209 157.186 1.00 122.86 ? 199 ASP A CA  1 
ATOM   1321  C C   . ASP A 1 176 ? 122.088 123.003 157.151 1.00 122.86 ? 199 ASP A C   1 
ATOM   1322  O O   . ASP A 1 176 ? 121.580 122.233 156.328 1.00 122.86 ? 199 ASP A O   1 
ATOM   1323  C CB  . ASP A 1 176 ? 124.239 122.343 158.271 1.00 122.86 ? 199 ASP A CB  1 
ATOM   1324  C CG  . ASP A 1 176 ? 124.002 120.859 158.054 1.00 122.86 ? 199 ASP A CG  1 
ATOM   1325  O OD1 . ASP A 1 176 ? 122.866 120.390 158.282 1.00 122.86 ? 199 ASP A OD1 1 
ATOM   1326  O OD2 . ASP A 1 176 ? 124.956 120.158 157.655 1.00 122.86 ? 199 ASP A OD2 1 
ATOM   1327  N N   . GLY A 1 177 ? 121.358 123.679 158.035 1.00 137.96 ? 200 GLY A N   1 
ATOM   1328  C CA  . GLY A 1 177 ? 119.913 123.570 158.059 1.00 137.96 ? 200 GLY A CA  1 
ATOM   1329  C C   . GLY A 1 177 ? 119.253 124.201 156.850 1.00 137.96 ? 200 GLY A C   1 
ATOM   1330  O O   . GLY A 1 177 ? 118.676 123.497 156.015 1.00 137.96 ? 200 GLY A O   1 
ATOM   1331  N N   . SER A 1 178 ? 119.341 125.529 156.748 1.00 145.08 ? 201 SER A N   1 
ATOM   1332  C CA  . SER A 1 178 ? 118.797 126.282 155.616 1.00 145.08 ? 201 SER A CA  1 
ATOM   1333  C C   . SER A 1 178 ? 117.310 125.990 155.414 1.00 145.08 ? 201 SER A C   1 
ATOM   1334  O O   . SER A 1 178 ? 116.841 125.763 154.297 1.00 145.08 ? 201 SER A O   1 
ATOM   1335  C CB  . SER A 1 178 ? 119.592 126.001 154.338 1.00 145.08 ? 201 SER A CB  1 
ATOM   1336  O OG  . SER A 1 178 ? 120.951 126.371 154.492 1.00 145.08 ? 201 SER A OG  1 
ATOM   1337  N N   . THR A 1 179 ? 116.566 125.997 156.515 1.00 170.73 ? 202 THR A N   1 
ATOM   1338  C CA  . THR A 1 179 ? 115.131 125.739 156.469 1.00 170.73 ? 202 THR A CA  1 
ATOM   1339  C C   . THR A 1 179 ? 114.381 126.922 155.865 1.00 170.73 ? 202 THR A C   1 
ATOM   1340  O O   . THR A 1 179 ? 113.321 126.756 155.262 1.00 170.73 ? 202 THR A O   1 
ATOM   1341  C CB  . THR A 1 179 ? 114.563 125.443 157.869 1.00 170.73 ? 202 THR A CB  1 
ATOM   1342  O OG1 . THR A 1 179 ? 113.198 125.021 157.755 1.00 170.73 ? 202 THR A OG1 1 
ATOM   1343  C CG2 . THR A 1 179 ? 114.632 126.684 158.745 1.00 170.73 ? 202 THR A CG2 1 
ATOM   1344  N N   . PRO B 2 5   ? 138.002 203.416 143.245 1.00 234.58 ? 27  PRO B N   1 
ATOM   1345  C CA  . PRO B 2 5   ? 137.581 203.471 141.841 1.00 234.58 ? 27  PRO B CA  1 
ATOM   1346  C C   . PRO B 2 5   ? 136.110 203.846 141.687 1.00 234.58 ? 27  PRO B C   1 
ATOM   1347  O O   . PRO B 2 5   ? 135.476 204.262 142.656 1.00 234.58 ? 27  PRO B O   1 
ATOM   1348  C CB  . PRO B 2 5   ? 137.834 202.046 141.347 1.00 234.58 ? 27  PRO B CB  1 
ATOM   1349  C CG  . PRO B 2 5   ? 137.687 201.204 142.564 1.00 234.58 ? 27  PRO B CG  1 
ATOM   1350  C CD  . PRO B 2 5   ? 138.207 202.032 143.707 1.00 234.58 ? 27  PRO B CD  1 
ATOM   1351  N N   . CYS B 2 6   ? 135.578 203.698 140.472 1.00 243.24 ? 28  CYS B N   1 
ATOM   1352  C CA  . CYS B 2 6   ? 134.182 204.026 140.219 1.00 243.24 ? 28  CYS B CA  1 
ATOM   1353  C C   . CYS B 2 6   ? 133.233 202.893 140.586 1.00 243.24 ? 28  CYS B C   1 
ATOM   1354  O O   . CYS B 2 6   ? 132.019 203.117 140.642 1.00 243.24 ? 28  CYS B O   1 
ATOM   1355  C CB  . CYS B 2 6   ? 133.984 204.401 138.748 1.00 243.24 ? 28  CYS B CB  1 
ATOM   1356  S SG  . CYS B 2 6   ? 134.688 205.997 138.278 1.00 243.24 ? 28  CYS B SG  1 
ATOM   1357  N N   . GLY B 2 7   ? 133.745 201.696 140.831 1.00 226.88 ? 29  GLY B N   1 
ATOM   1358  C CA  . GLY B 2 7   ? 132.881 200.585 141.198 1.00 226.88 ? 29  GLY B CA  1 
ATOM   1359  C C   . GLY B 2 7   ? 133.508 199.260 140.797 1.00 226.88 ? 29  GLY B C   1 
ATOM   1360  O O   . GLY B 2 7   ? 134.721 199.077 140.898 1.00 226.88 ? 29  GLY B O   1 
ATOM   1361  N N   . TYR B 2 8   ? 132.648 198.349 140.344 1.00 206.36 ? 30  TYR B N   1 
ATOM   1362  C CA  . TYR B 2 8   ? 133.063 197.011 139.948 1.00 206.36 ? 30  TYR B CA  1 
ATOM   1363  C C   . TYR B 2 8   ? 132.278 196.599 138.709 1.00 206.36 ? 30  TYR B C   1 
ATOM   1364  O O   . TYR B 2 8   ? 131.491 197.374 138.157 1.00 206.36 ? 30  TYR B O   1 
ATOM   1365  C CB  . TYR B 2 8   ? 132.864 196.008 141.092 1.00 206.36 ? 30  TYR B CB  1 
ATOM   1366  C CG  . TYR B 2 8   ? 131.450 195.954 141.628 1.00 206.36 ? 30  TYR B CG  1 
ATOM   1367  C CD1 . TYR B 2 8   ? 131.033 196.819 142.632 1.00 206.36 ? 30  TYR B CD1 1 
ATOM   1368  C CD2 . TYR B 2 8   ? 130.533 195.036 141.134 1.00 206.36 ? 30  TYR B CD2 1 
ATOM   1369  C CE1 . TYR B 2 8   ? 129.743 196.773 143.125 1.00 206.36 ? 30  TYR B CE1 1 
ATOM   1370  C CE2 . TYR B 2 8   ? 129.241 194.983 141.621 1.00 206.36 ? 30  TYR B CE2 1 
ATOM   1371  C CZ  . TYR B 2 8   ? 128.851 195.853 142.616 1.00 206.36 ? 30  TYR B CZ  1 
ATOM   1372  O OH  . TYR B 2 8   ? 127.565 195.802 143.104 1.00 206.36 ? 30  TYR B OH  1 
ATOM   1373  N N   . ILE B 2 9   ? 132.500 195.363 138.272 1.00 192.65 ? 31  ILE B N   1 
ATOM   1374  C CA  . ILE B 2 9   ? 131.820 194.790 137.116 1.00 192.65 ? 31  ILE B CA  1 
ATOM   1375  C C   . ILE B 2 9   ? 131.053 193.563 137.587 1.00 192.65 ? 31  ILE B C   1 
ATOM   1376  O O   . ILE B 2 9   ? 131.636 192.656 138.194 1.00 192.65 ? 31  ILE B O   1 
ATOM   1377  C CB  . ILE B 2 9   ? 132.806 194.424 135.996 1.00 192.65 ? 31  ILE B CB  1 
ATOM   1378  C CG1 . ILE B 2 9   ? 133.534 195.675 135.498 1.00 192.65 ? 31  ILE B CG1 1 
ATOM   1379  C CG2 . ILE B 2 9   ? 132.079 193.733 134.852 1.00 192.65 ? 31  ILE B CG2 1 
ATOM   1380  C CD1 . ILE B 2 9   ? 134.326 195.459 134.227 1.00 192.65 ? 31  ILE B CD1 1 
ATOM   1381  N N   . TYR B 2 10  ? 129.751 193.535 137.309 1.00 182.09 ? 32  TYR B N   1 
ATOM   1382  C CA  . TYR B 2 10  ? 128.898 192.429 137.712 1.00 182.09 ? 32  TYR B CA  1 
ATOM   1383  C C   . TYR B 2 10  ? 128.449 191.643 136.492 1.00 182.09 ? 32  TYR B C   1 
ATOM   1384  O O   . TYR B 2 10  ? 127.887 192.231 135.559 1.00 182.09 ? 32  TYR B O   1 
ATOM   1385  C CB  . TYR B 2 10  ? 127.675 192.943 138.480 1.00 182.09 ? 32  TYR B CB  1 
ATOM   1386  C CG  . TYR B 2 10  ? 127.173 191.991 139.540 1.00 182.09 ? 32  TYR B CG  1 
ATOM   1387  C CD1 . TYR B 2 10  ? 127.758 191.953 140.799 1.00 182.09 ? 32  TYR B CD1 1 
ATOM   1388  C CD2 . TYR B 2 10  ? 126.113 191.132 139.285 1.00 182.09 ? 32  TYR B CD2 1 
ATOM   1389  C CE1 . TYR B 2 10  ? 127.302 191.085 141.773 1.00 182.09 ? 32  TYR B CE1 1 
ATOM   1390  C CE2 . TYR B 2 10  ? 125.649 190.261 140.253 1.00 182.09 ? 32  TYR B CE2 1 
ATOM   1391  C CZ  . TYR B 2 10  ? 126.248 190.241 141.495 1.00 182.09 ? 32  TYR B CZ  1 
ATOM   1392  O OH  . TYR B 2 10  ? 125.791 189.375 142.461 1.00 182.09 ? 32  TYR B OH  1 
ATOM   1393  N N   . PRO B 2 11  ? 128.674 190.319 136.452 1.00 159.11 ? 33  PRO B N   1 
ATOM   1394  C CA  . PRO B 2 11  ? 129.332 189.544 137.510 1.00 159.11 ? 33  PRO B CA  1 
ATOM   1395  C C   . PRO B 2 11  ? 130.854 189.667 137.481 1.00 159.11 ? 33  PRO B C   1 
ATOM   1396  O O   . PRO B 2 11  ? 131.426 189.978 136.437 1.00 159.11 ? 33  PRO B O   1 
ATOM   1397  C CB  . PRO B 2 11  ? 128.901 188.111 137.203 1.00 159.11 ? 33  PRO B CB  1 
ATOM   1398  C CG  . PRO B 2 11  ? 128.746 188.095 135.725 1.00 159.11 ? 33  PRO B CG  1 
ATOM   1399  C CD  . PRO B 2 11  ? 128.236 189.460 135.337 1.00 159.11 ? 33  PRO B CD  1 
ATOM   1400  N N   . GLU B 2 12  ? 131.496 189.419 138.624 1.00 146.55 ? 34  GLU B N   1 
ATOM   1401  C CA  . GLU B 2 12  ? 132.947 189.556 138.700 1.00 146.55 ? 34  GLU B CA  1 
ATOM   1402  C C   . GLU B 2 12  ? 133.652 188.424 137.962 1.00 146.55 ? 34  GLU B C   1 
ATOM   1403  O O   . GLU B 2 12  ? 134.706 188.636 137.351 1.00 146.55 ? 34  GLU B O   1 
ATOM   1404  C CB  . GLU B 2 12  ? 133.392 189.605 140.162 1.00 146.55 ? 34  GLU B CB  1 
ATOM   1405  C CG  . GLU B 2 12  ? 134.887 189.805 140.350 1.00 146.55 ? 34  GLU B CG  1 
ATOM   1406  C CD  . GLU B 2 12  ? 135.284 189.871 141.811 1.00 146.55 ? 34  GLU B CD  1 
ATOM   1407  O OE1 . GLU B 2 12  ? 134.387 190.024 142.666 1.00 146.55 ? 34  GLU B OE1 1 
ATOM   1408  O OE2 . GLU B 2 12  ? 136.494 189.770 142.104 1.00 146.55 ? 34  GLU B OE2 1 
ATOM   1409  N N   . PHE B 2 13  ? 133.086 187.216 138.004 1.00 128.93 ? 35  PHE B N   1 
ATOM   1410  C CA  . PHE B 2 13  ? 133.652 186.041 137.345 1.00 128.93 ? 35  PHE B CA  1 
ATOM   1411  C C   . PHE B 2 13  ? 132.623 185.503 136.357 1.00 128.93 ? 35  PHE B C   1 
ATOM   1412  O O   . PHE B 2 13  ? 131.899 184.542 136.659 1.00 128.93 ? 35  PHE B O   1 
ATOM   1413  C CB  . PHE B 2 13  ? 134.053 184.972 138.360 1.00 128.93 ? 35  PHE B CB  1 
ATOM   1414  C CG  . PHE B 2 13  ? 135.079 185.435 139.354 1.00 128.93 ? 35  PHE B CG  1 
ATOM   1415  C CD1 . PHE B 2 13  ? 136.431 185.320 139.079 1.00 128.93 ? 35  PHE B CD1 1 
ATOM   1416  C CD2 . PHE B 2 13  ? 134.691 185.984 140.565 1.00 128.93 ? 35  PHE B CD2 1 
ATOM   1417  C CE1 . PHE B 2 13  ? 137.377 185.745 139.992 1.00 128.93 ? 35  PHE B CE1 1 
ATOM   1418  C CE2 . PHE B 2 13  ? 135.633 186.411 141.482 1.00 128.93 ? 35  PHE B CE2 1 
ATOM   1419  C CZ  . PHE B 2 13  ? 136.977 186.291 141.195 1.00 128.93 ? 35  PHE B CZ  1 
ATOM   1420  N N   . PRO B 2 14  ? 132.529 186.095 135.164 1.00 130.07 ? 36  PRO B N   1 
ATOM   1421  C CA  . PRO B 2 14  ? 131.533 185.646 134.179 1.00 130.07 ? 36  PRO B CA  1 
ATOM   1422  C C   . PRO B 2 14  ? 131.973 184.351 133.511 1.00 130.07 ? 36  PRO B C   1 
ATOM   1423  O O   . PRO B 2 14  ? 133.033 184.290 132.884 1.00 130.07 ? 36  PRO B O   1 
ATOM   1424  C CB  . PRO B 2 14  ? 131.477 186.807 133.180 1.00 130.07 ? 36  PRO B CB  1 
ATOM   1425  C CG  . PRO B 2 14  ? 132.825 187.438 133.268 1.00 130.07 ? 36  PRO B CG  1 
ATOM   1426  C CD  . PRO B 2 14  ? 133.304 187.254 134.685 1.00 130.07 ? 36  PRO B CD  1 
ATOM   1427  N N   . VAL B 2 15  ? 131.155 183.311 133.652 1.00 101.16 ? 37  VAL B N   1 
ATOM   1428  C CA  . VAL B 2 15  ? 131.397 182.013 133.031 1.00 101.16 ? 37  VAL B CA  1 
ATOM   1429  C C   . VAL B 2 15  ? 130.118 181.613 132.311 1.00 101.16 ? 37  VAL B C   1 
ATOM   1430  O O   . VAL B 2 15  ? 129.122 181.262 132.956 1.00 101.16 ? 37  VAL B O   1 
ATOM   1431  C CB  . VAL B 2 15  ? 131.806 180.942 134.051 1.00 101.16 ? 37  VAL B CB  1 
ATOM   1432  C CG1 . VAL B 2 15  ? 132.030 179.608 133.356 1.00 101.16 ? 37  VAL B CG1 1 
ATOM   1433  C CG2 . VAL B 2 15  ? 133.056 181.370 134.805 1.00 101.16 ? 37  VAL B CG2 1 
ATOM   1434  N N   . VAL B 2 16  ? 130.137 181.667 130.981 1.00 112.69 ? 38  VAL B N   1 
ATOM   1435  C CA  . VAL B 2 16  ? 128.971 181.371 130.159 1.00 112.69 ? 38  VAL B CA  1 
ATOM   1436  C C   . VAL B 2 16  ? 129.306 180.215 129.229 1.00 112.69 ? 38  VAL B C   1 
ATOM   1437  O O   . VAL B 2 16  ? 130.408 180.151 128.673 1.00 112.69 ? 38  VAL B O   1 
ATOM   1438  C CB  . VAL B 2 16  ? 128.517 182.605 129.353 1.00 112.69 ? 38  VAL B CB  1 
ATOM   1439  C CG1 . VAL B 2 16  ? 127.211 182.320 128.627 1.00 112.69 ? 38  VAL B CG1 1 
ATOM   1440  C CG2 . VAL B 2 16  ? 128.370 183.808 130.267 1.00 112.69 ? 38  VAL B CG2 1 
ATOM   1441  N N   . GLN B 2 17  ? 128.352 179.302 129.064 1.00 120.72 ? 39  GLN B N   1 
ATOM   1442  C CA  . GLN B 2 17  ? 128.534 178.182 128.153 1.00 120.72 ? 39  GLN B CA  1 
ATOM   1443  C C   . GLN B 2 17  ? 128.570 178.671 126.711 1.00 120.72 ? 39  GLN B C   1 
ATOM   1444  O O   . GLN B 2 17  ? 127.841 179.592 126.333 1.00 120.72 ? 39  GLN B O   1 
ATOM   1445  C CB  . GLN B 2 17  ? 127.408 177.164 128.337 1.00 120.72 ? 39  GLN B CB  1 
ATOM   1446  C CG  . GLN B 2 17  ? 127.532 175.922 127.469 1.00 120.72 ? 39  GLN B CG  1 
ATOM   1447  C CD  . GLN B 2 17  ? 126.335 175.002 127.597 1.00 120.72 ? 39  GLN B CD  1 
ATOM   1448  O OE1 . GLN B 2 17  ? 125.347 175.336 128.251 1.00 120.72 ? 39  GLN B OE1 1 
ATOM   1449  N NE2 . GLN B 2 17  ? 126.417 173.834 126.970 1.00 120.72 ? 39  GLN B NE2 1 
ATOM   1450  N N   . ARG B 2 18  ? 129.434 178.054 125.907 1.00 118.47 ? 40  ARG B N   1 
ATOM   1451  C CA  . ARG B 2 18  ? 129.553 178.433 124.505 1.00 118.47 ? 40  ARG B CA  1 
ATOM   1452  C C   . ARG B 2 18  ? 128.248 178.161 123.768 1.00 118.47 ? 40  ARG B C   1 
ATOM   1453  O O   . ARG B 2 18  ? 127.702 177.056 123.832 1.00 118.47 ? 40  ARG B O   1 
ATOM   1454  C CB  . ARG B 2 18  ? 130.703 177.669 123.849 1.00 118.47 ? 40  ARG B CB  1 
ATOM   1455  C CG  . ARG B 2 18  ? 132.069 177.993 124.429 1.00 118.47 ? 40  ARG B CG  1 
ATOM   1456  C CD  . ARG B 2 18  ? 133.178 177.308 123.649 1.00 118.47 ? 40  ARG B CD  1 
ATOM   1457  N NE  . ARG B 2 18  ? 134.500 177.659 124.160 1.00 118.47 ? 40  ARG B NE  1 
ATOM   1458  C CZ  . ARG B 2 18  ? 135.641 177.214 123.647 1.00 118.47 ? 40  ARG B CZ  1 
ATOM   1459  N NH1 . ARG B 2 18  ? 135.627 176.396 122.604 1.00 118.47 ? 40  ARG B NH1 1 
ATOM   1460  N NH2 . ARG B 2 18  ? 136.799 177.586 124.177 1.00 118.47 ? 40  ARG B NH2 1 
ATOM   1461  N N   . GLY B 2 19  ? 127.752 179.174 123.069 1.00 150.00 ? 41  GLY B N   1 
ATOM   1462  C CA  . GLY B 2 19  ? 126.500 179.070 122.353 1.00 150.00 ? 41  GLY B CA  1 
ATOM   1463  C C   . GLY B 2 19  ? 125.305 179.705 123.028 1.00 150.00 ? 41  GLY B C   1 
ATOM   1464  O O   . GLY B 2 19  ? 124.175 179.273 122.772 1.00 150.00 ? 41  GLY B O   1 
ATOM   1465  N N   . SER B 2 20  ? 125.512 180.709 123.879 1.00 158.47 ? 42  SER B N   1 
ATOM   1466  C CA  . SER B 2 20  ? 124.428 181.368 124.590 1.00 158.47 ? 42  SER B CA  1 
ATOM   1467  C C   . SER B 2 20  ? 124.693 182.868 124.614 1.00 158.47 ? 42  SER B C   1 
ATOM   1468  O O   . SER B 2 20  ? 125.663 183.360 124.029 1.00 158.47 ? 42  SER B O   1 
ATOM   1469  C CB  . SER B 2 20  ? 124.275 180.807 126.008 1.00 158.47 ? 42  SER B CB  1 
ATOM   1470  O OG  . SER B 2 20  ? 124.357 179.392 126.007 1.00 158.47 ? 42  SER B OG  1 
ATOM   1471  N N   . ASN B 2 21  ? 123.819 183.598 125.300 1.00 179.22 ? 43  ASN B N   1 
ATOM   1472  C CA  . ASN B 2 21  ? 123.930 185.043 125.413 1.00 179.22 ? 43  ASN B CA  1 
ATOM   1473  C C   . ASN B 2 21  ? 124.690 185.429 126.680 1.00 179.22 ? 43  ASN B C   1 
ATOM   1474  O O   . ASN B 2 21  ? 124.967 184.602 127.551 1.00 179.22 ? 43  ASN B O   1 
ATOM   1475  C CB  . ASN B 2 21  ? 122.544 185.687 125.408 1.00 179.22 ? 43  ASN B CB  1 
ATOM   1476  C CG  . ASN B 2 21  ? 121.911 185.697 124.033 1.00 179.22 ? 43  ASN B CG  1 
ATOM   1477  O OD1 . ASN B 2 21  ? 122.602 185.813 123.020 1.00 179.22 ? 43  ASN B OD1 1 
ATOM   1478  N ND2 . ASN B 2 21  ? 120.586 185.574 123.991 1.00 179.22 ? 43  ASN B ND2 1 
ATOM   1479  N N   . PHE B 2 22  ? 125.027 186.714 126.774 1.00 169.69 ? 44  PHE B N   1 
ATOM   1480  C CA  . PHE B 2 22  ? 125.722 187.239 127.940 1.00 169.69 ? 44  PHE B CA  1 
ATOM   1481  C C   . PHE B 2 22  ? 125.538 188.749 127.989 1.00 169.69 ? 44  PHE B C   1 
ATOM   1482  O O   . PHE B 2 22  ? 125.524 189.411 126.948 1.00 169.69 ? 44  PHE B O   1 
ATOM   1483  C CB  . PHE B 2 22  ? 127.214 186.889 127.913 1.00 169.69 ? 44  PHE B CB  1 
ATOM   1484  C CG  . PHE B 2 22  ? 128.016 187.581 128.976 1.00 169.69 ? 44  PHE B CG  1 
ATOM   1485  C CD1 . PHE B 2 22  ? 128.945 188.550 128.642 1.00 169.69 ? 44  PHE B CD1 1 
ATOM   1486  C CD2 . PHE B 2 22  ? 127.831 187.269 130.313 1.00 169.69 ? 44  PHE B CD2 1 
ATOM   1487  C CE1 . PHE B 2 22  ? 129.682 189.191 129.621 1.00 169.69 ? 44  PHE B CE1 1 
ATOM   1488  C CE2 . PHE B 2 22  ? 128.564 187.905 131.296 1.00 169.69 ? 44  PHE B CE2 1 
ATOM   1489  C CZ  . PHE B 2 22  ? 129.490 188.867 130.949 1.00 169.69 ? 44  PHE B CZ  1 
ATOM   1490  N N   . THR B 2 23  ? 125.398 189.282 129.202 1.00 174.84 ? 45  THR B N   1 
ATOM   1491  C CA  . THR B 2 23  ? 125.241 190.716 129.403 1.00 174.84 ? 45  THR B CA  1 
ATOM   1492  C C   . THR B 2 23  ? 125.886 191.102 130.724 1.00 174.84 ? 45  THR B C   1 
ATOM   1493  O O   . THR B 2 23  ? 125.594 190.494 131.758 1.00 174.84 ? 45  THR B O   1 
ATOM   1494  C CB  . THR B 2 23  ? 123.762 191.122 129.394 1.00 174.84 ? 45  THR B CB  1 
ATOM   1495  O OG1 . THR B 2 23  ? 123.188 190.816 128.117 1.00 174.84 ? 45  THR B OG1 1 
ATOM   1496  C CG2 . THR B 2 23  ? 123.615 192.611 129.665 1.00 174.84 ? 45  THR B CG2 1 
ATOM   1497  N N   . ALA B 2 24  ? 126.758 192.106 130.686 1.00 187.14 ? 46  ALA B N   1 
ATOM   1498  C CA  . ALA B 2 24  ? 127.462 192.585 131.865 1.00 187.14 ? 46  ALA B CA  1 
ATOM   1499  C C   . ALA B 2 24  ? 127.175 194.066 132.082 1.00 187.14 ? 46  ALA B C   1 
ATOM   1500  O O   . ALA B 2 24  ? 126.732 194.776 131.175 1.00 187.14 ? 46  ALA B O   1 
ATOM   1501  C CB  . ALA B 2 24  ? 128.974 192.357 131.743 1.00 187.14 ? 46  ALA B CB  1 
ATOM   1502  N N   . ILE B 2 25  ? 127.437 194.526 133.306 1.00 200.44 ? 47  ILE B N   1 
ATOM   1503  C CA  . ILE B 2 25  ? 127.217 195.912 133.691 1.00 200.44 ? 47  ILE B CA  1 
ATOM   1504  C C   . ILE B 2 25  ? 128.501 196.472 134.285 1.00 200.44 ? 47  ILE B C   1 
ATOM   1505  O O   . ILE B 2 25  ? 129.412 195.736 134.670 1.00 200.44 ? 47  ILE B O   1 
ATOM   1506  C CB  . ILE B 2 25  ? 126.052 196.065 134.694 1.00 200.44 ? 47  ILE B CB  1 
ATOM   1507  C CG1 . ILE B 2 25  ? 126.381 195.351 136.007 1.00 200.44 ? 47  ILE B CG1 1 
ATOM   1508  C CG2 . ILE B 2 25  ? 124.759 195.528 134.103 1.00 200.44 ? 47  ILE B CG2 1 
ATOM   1509  C CD1 . ILE B 2 25  ? 125.302 195.483 137.060 1.00 200.44 ? 47  ILE B CD1 1 
ATOM   1510  N N   . CYS B 2 26  ? 128.562 197.802 134.356 1.00 217.55 ? 48  CYS B N   1 
ATOM   1511  C CA  . CYS B 2 26  ? 129.711 198.510 134.923 1.00 217.55 ? 48  CYS B CA  1 
ATOM   1512  C C   . CYS B 2 26  ? 129.178 199.756 135.624 1.00 217.55 ? 48  CYS B C   1 
ATOM   1513  O O   . CYS B 2 26  ? 128.949 200.786 134.982 1.00 217.55 ? 48  CYS B O   1 
ATOM   1514  C CB  . CYS B 2 26  ? 130.730 198.865 133.846 1.00 217.55 ? 48  CYS B CB  1 
ATOM   1515  S SG  . CYS B 2 26  ? 132.136 199.845 134.425 1.00 217.55 ? 48  CYS B SG  1 
ATOM   1516  N N   . VAL B 2 27  ? 128.983 199.658 136.936 1.00 230.65 ? 49  VAL B N   1 
ATOM   1517  C CA  . VAL B 2 27  ? 128.397 200.746 137.711 1.00 230.65 ? 49  VAL B CA  1 
ATOM   1518  C C   . VAL B 2 27  ? 129.476 201.760 138.062 1.00 230.65 ? 49  VAL B C   1 
ATOM   1519  O O   . VAL B 2 27  ? 130.616 201.397 138.378 1.00 230.65 ? 49  VAL B O   1 
ATOM   1520  C CB  . VAL B 2 27  ? 127.712 200.197 138.975 1.00 230.65 ? 49  VAL B CB  1 
ATOM   1521  C CG1 . VAL B 2 27  ? 126.878 201.280 139.644 1.00 230.65 ? 49  VAL B CG1 1 
ATOM   1522  C CG2 . VAL B 2 27  ? 126.852 198.992 138.631 1.00 230.65 ? 49  VAL B CG2 1 
ATOM   1523  N N   . LEU B 2 28  ? 129.118 203.040 138.006 1.00 237.77 ? 50  LEU B N   1 
ATOM   1524  C CA  . LEU B 2 28  ? 130.020 204.134 138.338 1.00 237.77 ? 50  LEU B CA  1 
ATOM   1525  C C   . LEU B 2 28  ? 129.551 204.806 139.621 1.00 237.77 ? 50  LEU B C   1 
ATOM   1526  O O   . LEU B 2 28  ? 128.364 205.117 139.765 1.00 237.77 ? 50  LEU B O   1 
ATOM   1527  C CB  . LEU B 2 28  ? 130.085 205.154 137.199 1.00 237.77 ? 50  LEU B CB  1 
ATOM   1528  C CG  . LEU B 2 28  ? 130.401 204.606 135.806 1.00 237.77 ? 50  LEU B CG  1 
ATOM   1529  C CD1 . LEU B 2 28  ? 130.425 205.728 134.779 1.00 237.77 ? 50  LEU B CD1 1 
ATOM   1530  C CD2 . LEU B 2 28  ? 131.721 203.850 135.811 1.00 237.77 ? 50  LEU B CD2 1 
ATOM   1531  N N   . LYS B 2 29  ? 130.481 205.028 140.546 1.00 247.69 ? 51  LYS B N   1 
ATOM   1532  C CA  . LYS B 2 29  ? 130.153 205.688 141.799 1.00 247.69 ? 51  LYS B CA  1 
ATOM   1533  C C   . LYS B 2 29  ? 129.943 207.183 141.580 1.00 247.69 ? 51  LYS B C   1 
ATOM   1534  O O   . LYS B 2 29  ? 130.344 207.753 140.562 1.00 247.69 ? 51  LYS B O   1 
ATOM   1535  C CB  . LYS B 2 29  ? 131.254 205.460 142.836 1.00 247.69 ? 51  LYS B CB  1 
ATOM   1536  C CG  . LYS B 2 29  ? 131.165 204.126 143.559 1.00 247.69 ? 51  LYS B CG  1 
ATOM   1537  C CD  . LYS B 2 29  ? 132.323 203.945 144.528 1.00 247.69 ? 51  LYS B CD  1 
ATOM   1538  C CE  . LYS B 2 29  ? 132.256 202.595 145.223 1.00 247.69 ? 51  LYS B CE  1 
ATOM   1539  N NZ  . LYS B 2 29  ? 133.412 202.384 146.138 1.00 247.69 ? 51  LYS B NZ  1 
ATOM   1540  N N   . GLU B 2 30  ? 129.303 207.820 142.563 1.00 251.72 ? 52  GLU B N   1 
ATOM   1541  C CA  . GLU B 2 30  ? 129.016 209.247 142.460 1.00 251.72 ? 52  GLU B CA  1 
ATOM   1542  C C   . GLU B 2 30  ? 130.252 210.101 142.711 1.00 251.72 ? 52  GLU B C   1 
ATOM   1543  O O   . GLU B 2 30  ? 130.322 211.235 142.224 1.00 251.72 ? 52  GLU B O   1 
ATOM   1544  C CB  . GLU B 2 30  ? 127.905 209.631 143.439 1.00 251.72 ? 52  GLU B CB  1 
ATOM   1545  C CG  . GLU B 2 30  ? 126.561 208.987 143.135 1.00 251.72 ? 52  GLU B CG  1 
ATOM   1546  C CD  . GLU B 2 30  ? 125.947 209.494 141.844 1.00 251.72 ? 52  GLU B CD  1 
ATOM   1547  O OE1 . GLU B 2 30  ? 126.198 210.664 141.483 1.00 251.72 ? 52  GLU B OE1 1 
ATOM   1548  O OE2 . GLU B 2 30  ? 125.215 208.723 141.189 1.00 251.72 ? 52  GLU B OE2 1 
ATOM   1549  N N   . ALA B 2 31  ? 131.229 209.579 143.456 1.00 252.28 ? 53  ALA B N   1 
ATOM   1550  C CA  . ALA B 2 31  ? 132.448 210.334 143.729 1.00 252.28 ? 53  ALA B CA  1 
ATOM   1551  C C   . ALA B 2 31  ? 133.184 210.667 142.437 1.00 252.28 ? 53  ALA B C   1 
ATOM   1552  O O   . ALA B 2 31  ? 133.393 211.841 142.108 1.00 252.28 ? 53  ALA B O   1 
ATOM   1553  C CB  . ALA B 2 31  ? 133.348 209.545 144.682 1.00 252.28 ? 53  ALA B CB  1 
ATOM   1554  N N   . CYS B 2 32  ? 133.584 209.639 141.686 1.00 256.60 ? 54  CYS B N   1 
ATOM   1555  C CA  . CYS B 2 32  ? 134.240 209.876 140.406 1.00 256.60 ? 54  CYS B CA  1 
ATOM   1556  C C   . CYS B 2 32  ? 133.298 210.501 139.386 1.00 256.60 ? 54  CYS B C   1 
ATOM   1557  O O   . CYS B 2 32  ? 133.765 211.191 138.474 1.00 256.60 ? 54  CYS B O   1 
ATOM   1558  C CB  . CYS B 2 32  ? 134.820 208.571 139.859 1.00 256.60 ? 54  CYS B CB  1 
ATOM   1559  S SG  . CYS B 2 32  ? 133.597 207.355 139.323 1.00 256.60 ? 54  CYS B SG  1 
ATOM   1560  N N   . LEU B 2 33  ? 131.988 210.284 139.524 1.00 254.50 ? 55  LEU B N   1 
ATOM   1561  C CA  . LEU B 2 33  ? 131.028 210.938 138.640 1.00 254.50 ? 55  LEU B CA  1 
ATOM   1562  C C   . LEU B 2 33  ? 131.093 212.453 138.790 1.00 254.50 ? 55  LEU B C   1 
ATOM   1563  O O   . LEU B 2 33  ? 131.061 213.190 137.799 1.00 254.50 ? 55  LEU B O   1 
ATOM   1564  C CB  . LEU B 2 33  ? 129.616 210.427 138.930 1.00 254.50 ? 55  LEU B CB  1 
ATOM   1565  C CG  . LEU B 2 33  ? 128.502 210.872 137.980 1.00 254.50 ? 55  LEU B CG  1 
ATOM   1566  C CD1 . LEU B 2 33  ? 128.955 210.787 136.531 1.00 254.50 ? 55  LEU B CD1 1 
ATOM   1567  C CD2 . LEU B 2 33  ? 127.246 210.042 138.202 1.00 254.50 ? 55  LEU B CD2 1 
ATOM   1568  N N   . GLN B 2 34  ? 131.183 212.935 140.031 1.00 253.01 ? 56  GLN B N   1 
ATOM   1569  C CA  . GLN B 2 34  ? 131.298 214.370 140.263 1.00 253.01 ? 56  GLN B CA  1 
ATOM   1570  C C   . GLN B 2 34  ? 132.717 214.874 140.033 1.00 253.01 ? 56  GLN B C   1 
ATOM   1571  O O   . GLN B 2 34  ? 132.906 216.051 139.707 1.00 253.01 ? 56  GLN B O   1 
ATOM   1572  C CB  . GLN B 2 34  ? 130.846 214.712 141.683 1.00 253.01 ? 56  GLN B CB  1 
ATOM   1573  C CG  . GLN B 2 34  ? 129.368 214.474 141.941 1.00 253.01 ? 56  GLN B CG  1 
ATOM   1574  C CD  . GLN B 2 34  ? 128.945 214.897 143.334 1.00 253.01 ? 56  GLN B CD  1 
ATOM   1575  O OE1 . GLN B 2 34  ? 129.757 215.387 144.119 1.00 253.01 ? 56  GLN B OE1 1 
ATOM   1576  N NE2 . GLN B 2 34  ? 127.669 214.711 143.647 1.00 253.01 ? 56  GLN B NE2 1 
ATOM   1577  N N   . HIS B 2 35  ? 133.719 214.009 140.198 1.00 249.92 ? 57  HIS B N   1 
ATOM   1578  C CA  . HIS B 2 35  ? 135.104 214.434 140.027 1.00 249.92 ? 57  HIS B CA  1 
ATOM   1579  C C   . HIS B 2 35  ? 135.460 214.614 138.555 1.00 249.92 ? 57  HIS B C   1 
ATOM   1580  O O   . HIS B 2 35  ? 136.084 215.612 138.178 1.00 249.92 ? 57  HIS B O   1 
ATOM   1581  C CB  . HIS B 2 35  ? 136.046 213.426 140.688 1.00 249.92 ? 57  HIS B CB  1 
ATOM   1582  C CG  . HIS B 2 35  ? 137.486 213.831 140.653 1.00 249.92 ? 57  HIS B CG  1 
ATOM   1583  N ND1 . HIS B 2 35  ? 137.951 214.981 141.253 1.00 249.92 ? 57  HIS B ND1 1 
ATOM   1584  C CD2 . HIS B 2 35  ? 138.566 213.238 140.091 1.00 249.92 ? 57  HIS B CD2 1 
ATOM   1585  C CE1 . HIS B 2 35  ? 139.254 215.080 141.062 1.00 249.92 ? 57  HIS B CE1 1 
ATOM   1586  N NE2 . HIS B 2 35  ? 139.652 214.034 140.359 1.00 249.92 ? 57  HIS B NE2 1 
ATOM   1587  N N   . TYR B 2 36  ? 135.073 213.658 137.709 1.00 253.56 ? 58  TYR B N   1 
ATOM   1588  C CA  . TYR B 2 36  ? 135.429 213.692 136.297 1.00 253.56 ? 58  TYR B CA  1 
ATOM   1589  C C   . TYR B 2 36  ? 134.334 214.260 135.405 1.00 253.56 ? 58  TYR B C   1 
ATOM   1590  O O   . TYR B 2 36  ? 134.626 214.634 134.263 1.00 253.56 ? 58  TYR B O   1 
ATOM   1591  C CB  . TYR B 2 36  ? 135.787 212.283 135.807 1.00 253.56 ? 58  TYR B CB  1 
ATOM   1592  C CG  . TYR B 2 36  ? 136.989 211.681 136.498 1.00 253.56 ? 58  TYR B CG  1 
ATOM   1593  C CD1 . TYR B 2 36  ? 138.275 211.924 136.034 1.00 253.56 ? 58  TYR B CD1 1 
ATOM   1594  C CD2 . TYR B 2 36  ? 136.838 210.868 137.614 1.00 253.56 ? 58  TYR B CD2 1 
ATOM   1595  C CE1 . TYR B 2 36  ? 139.377 211.375 136.662 1.00 253.56 ? 58  TYR B CE1 1 
ATOM   1596  C CE2 . TYR B 2 36  ? 137.934 210.315 138.249 1.00 253.56 ? 58  TYR B CE2 1 
ATOM   1597  C CZ  . TYR B 2 36  ? 139.200 210.572 137.769 1.00 253.56 ? 58  TYR B CZ  1 
ATOM   1598  O OH  . TYR B 2 36  ? 140.294 210.024 138.398 1.00 253.56 ? 58  TYR B OH  1 
ATOM   1599  N N   . TYR B 2 37  ? 133.093 214.332 135.894 1.00 255.71 ? 59  TYR B N   1 
ATOM   1600  C CA  . TYR B 2 37  ? 131.955 214.826 135.117 1.00 255.71 ? 59  TYR B CA  1 
ATOM   1601  C C   . TYR B 2 37  ? 131.734 214.006 133.848 1.00 255.71 ? 59  TYR B C   1 
ATOM   1602  O O   . TYR B 2 37  ? 131.350 214.543 132.806 1.00 255.71 ? 59  TYR B O   1 
ATOM   1603  C CB  . TYR B 2 37  ? 132.112 216.311 134.772 1.00 255.71 ? 59  TYR B CB  1 
ATOM   1604  C CG  . TYR B 2 37  ? 132.480 217.181 135.953 1.00 255.71 ? 59  TYR B CG  1 
ATOM   1605  C CD1 . TYR B 2 37  ? 131.507 217.637 136.833 1.00 255.71 ? 59  TYR B CD1 1 
ATOM   1606  C CD2 . TYR B 2 37  ? 133.799 217.548 136.186 1.00 255.71 ? 59  TYR B CD2 1 
ATOM   1607  C CE1 . TYR B 2 37  ? 131.838 218.433 137.913 1.00 255.71 ? 59  TYR B CE1 1 
ATOM   1608  C CE2 . TYR B 2 37  ? 134.139 218.343 137.264 1.00 255.71 ? 59  TYR B CE2 1 
ATOM   1609  C CZ  . TYR B 2 37  ? 133.155 218.783 138.124 1.00 255.71 ? 59  TYR B CZ  1 
ATOM   1610  O OH  . TYR B 2 37  ? 133.489 219.575 139.198 1.00 255.71 ? 59  TYR B OH  1 
ATOM   1611  N N   . VAL B 2 38  ? 131.975 212.700 133.927 1.00 254.79 ? 60  VAL B N   1 
ATOM   1612  C CA  . VAL B 2 38  ? 131.792 211.785 132.806 1.00 254.79 ? 60  VAL B CA  1 
ATOM   1613  C C   . VAL B 2 38  ? 130.675 210.820 133.178 1.00 254.79 ? 60  VAL B C   1 
ATOM   1614  O O   . VAL B 2 38  ? 130.847 209.965 134.056 1.00 254.79 ? 60  VAL B O   1 
ATOM   1615  C CB  . VAL B 2 38  ? 133.085 211.031 132.465 1.00 254.79 ? 60  VAL B CB  1 
ATOM   1616  C CG1 . VAL B 2 38  ? 132.946 210.320 131.133 1.00 254.79 ? 60  VAL B CG1 1 
ATOM   1617  C CG2 . VAL B 2 38  ? 134.266 211.988 132.436 1.00 254.79 ? 60  VAL B CG2 1 
ATOM   1618  N N   . ASN B 2 39  ? 129.532 210.947 132.510 1.00 245.39 ? 61  ASN B N   1 
ATOM   1619  C CA  . ASN B 2 39  ? 128.381 210.102 132.788 1.00 245.39 ? 61  ASN B CA  1 
ATOM   1620  C C   . ASN B 2 39  ? 128.550 208.753 132.091 1.00 245.39 ? 61  ASN B C   1 
ATOM   1621  O O   . ASN B 2 39  ? 129.610 208.435 131.545 1.00 245.39 ? 61  ASN B O   1 
ATOM   1622  C CB  . ASN B 2 39  ? 127.092 210.805 132.367 1.00 245.39 ? 61  ASN B CB  1 
ATOM   1623  C CG  . ASN B 2 39  ? 125.961 210.590 133.361 1.00 245.39 ? 61  ASN B CG  1 
ATOM   1624  O OD1 . ASN B 2 39  ? 126.125 209.836 134.320 1.00 245.39 ? 61  ASN B OD1 1 
ATOM   1625  N ND2 . ASN B 2 39  ? 124.809 211.244 133.152 1.00 245.39 ? 61  ASN B ND2 1 
ATOM   1626  N N   . ALA B 2 40  ? 127.494 207.940 132.102 1.00 236.52 ? 62  ALA B N   1 
ATOM   1627  C CA  . ALA B 2 40  ? 127.529 206.617 131.493 1.00 236.52 ? 62  ALA B CA  1 
ATOM   1628  C C   . ALA B 2 40  ? 127.390 206.651 129.977 1.00 236.52 ? 62  ALA B C   1 
ATOM   1629  O O   . ALA B 2 40  ? 127.253 205.588 129.362 1.00 236.52 ? 62  ALA B O   1 
ATOM   1630  C CB  . ALA B 2 40  ? 126.429 205.735 132.089 1.00 236.52 ? 62  ALA B CB  1 
ATOM   1631  N N   . SER B 2 41  ? 127.413 207.832 129.361 1.00 238.31 ? 63  SER B N   1 
ATOM   1632  C CA  . SER B 2 41  ? 127.310 207.939 127.912 1.00 238.31 ? 63  SER B CA  1 
ATOM   1633  C C   . SER B 2 41  ? 128.662 207.905 127.214 1.00 238.31 ? 63  SER B C   1 
ATOM   1634  O O   . SER B 2 41  ? 128.739 207.445 126.069 1.00 238.31 ? 63  SER B O   1 
ATOM   1635  C CB  . SER B 2 41  ? 126.578 209.229 127.527 1.00 238.31 ? 63  SER B CB  1 
ATOM   1636  O OG  . SER B 2 41  ? 127.058 210.330 128.280 1.00 238.31 ? 63  SER B OG  1 
ATOM   1637  N N   . TYR B 2 42  ? 129.721 208.373 127.869 1.00 236.87 ? 64  TYR B N   1 
ATOM   1638  C CA  . TYR B 2 42  ? 131.054 208.409 127.284 1.00 236.87 ? 64  TYR B CA  1 
ATOM   1639  C C   . TYR B 2 42  ? 131.854 207.141 127.555 1.00 236.87 ? 64  TYR B C   1 
ATOM   1640  O O   . TYR B 2 42  ? 133.070 207.132 127.337 1.00 236.87 ? 64  TYR B O   1 
ATOM   1641  C CB  . TYR B 2 42  ? 131.826 209.624 127.803 1.00 236.87 ? 64  TYR B CB  1 
ATOM   1642  C CG  . TYR B 2 42  ? 131.604 210.887 127.002 1.00 236.87 ? 64  TYR B CG  1 
ATOM   1643  C CD1 . TYR B 2 42  ? 132.408 211.191 125.912 1.00 236.87 ? 64  TYR B CD1 1 
ATOM   1644  C CD2 . TYR B 2 42  ? 130.593 211.777 127.340 1.00 236.87 ? 64  TYR B CD2 1 
ATOM   1645  C CE1 . TYR B 2 42  ? 132.210 212.345 125.178 1.00 236.87 ? 64  TYR B CE1 1 
ATOM   1646  C CE2 . TYR B 2 42  ? 130.388 212.933 126.612 1.00 236.87 ? 64  TYR B CE2 1 
ATOM   1647  C CZ  . TYR B 2 42  ? 131.199 213.212 125.533 1.00 236.87 ? 64  TYR B CZ  1 
ATOM   1648  O OH  . TYR B 2 42  ? 130.998 214.363 124.805 1.00 236.87 ? 64  TYR B OH  1 
ATOM   1649  N N   . ILE B 2 43  ? 131.208 206.080 128.026 1.00 230.66 ? 65  ILE B N   1 
ATOM   1650  C CA  . ILE B 2 43  ? 131.898 204.824 128.292 1.00 230.66 ? 65  ILE B CA  1 
ATOM   1651  C C   . ILE B 2 43  ? 132.192 204.124 126.972 1.00 230.66 ? 65  ILE B C   1 
ATOM   1652  O O   . ILE B 2 43  ? 131.375 204.142 126.042 1.00 230.66 ? 65  ILE B O   1 
ATOM   1653  C CB  . ILE B 2 43  ? 131.064 203.936 129.235 1.00 230.66 ? 65  ILE B CB  1 
ATOM   1654  C CG1 . ILE B 2 43  ? 131.828 202.658 129.591 1.00 230.66 ? 65  ILE B CG1 1 
ATOM   1655  C CG2 . ILE B 2 43  ? 129.711 203.606 128.620 1.00 230.66 ? 65  ILE B CG2 1 
ATOM   1656  C CD1 . ILE B 2 43  ? 131.076 201.738 130.527 1.00 230.66 ? 65  ILE B CD1 1 
ATOM   1657  N N   . VAL B 2 44  ? 133.374 203.520 126.877 1.00 223.56 ? 66  VAL B N   1 
ATOM   1658  C CA  . VAL B 2 44  ? 133.804 202.793 125.686 1.00 223.56 ? 66  VAL B CA  1 
ATOM   1659  C C   . VAL B 2 44  ? 134.260 201.417 126.154 1.00 223.56 ? 66  VAL B C   1 
ATOM   1660  O O   . VAL B 2 44  ? 135.356 201.272 126.707 1.00 223.56 ? 66  VAL B O   1 
ATOM   1661  C CB  . VAL B 2 44  ? 134.919 203.517 124.924 1.00 223.56 ? 66  VAL B CB  1 
ATOM   1662  C CG1 . VAL B 2 44  ? 135.406 202.664 123.762 1.00 223.56 ? 66  VAL B CG1 1 
ATOM   1663  C CG2 . VAL B 2 44  ? 134.431 204.869 124.426 1.00 223.56 ? 66  VAL B CG2 1 
ATOM   1664  N N   . TRP B 2 45  ? 133.423 200.406 125.941 1.00 211.71 ? 67  TRP B N   1 
ATOM   1665  C CA  . TRP B 2 45  ? 133.776 199.049 126.329 1.00 211.71 ? 67  TRP B CA  1 
ATOM   1666  C C   . TRP B 2 45  ? 134.872 198.509 125.419 1.00 211.71 ? 67  TRP B C   1 
ATOM   1667  O O   . TRP B 2 45  ? 134.860 198.730 124.205 1.00 211.71 ? 67  TRP B O   1 
ATOM   1668  C CB  . TRP B 2 45  ? 132.547 198.142 126.272 1.00 211.71 ? 67  TRP B CB  1 
ATOM   1669  C CG  . TRP B 2 45  ? 131.441 198.569 127.189 1.00 211.71 ? 67  TRP B CG  1 
ATOM   1670  C CD1 . TRP B 2 45  ? 130.615 199.644 127.033 1.00 211.71 ? 67  TRP B CD1 1 
ATOM   1671  C CD2 . TRP B 2 45  ? 131.037 197.927 128.405 1.00 211.71 ? 67  TRP B CD2 1 
ATOM   1672  N NE1 . TRP B 2 45  ? 129.724 199.712 128.076 1.00 211.71 ? 67  TRP B NE1 1 
ATOM   1673  C CE2 . TRP B 2 45  ? 129.962 198.670 128.933 1.00 211.71 ? 67  TRP B CE2 1 
ATOM   1674  C CE3 . TRP B 2 45  ? 131.480 196.797 129.099 1.00 211.71 ? 67  TRP B CE3 1 
ATOM   1675  C CZ2 . TRP B 2 45  ? 129.324 198.319 130.120 1.00 211.71 ? 67  TRP B CZ2 1 
ATOM   1676  C CZ3 . TRP B 2 45  ? 130.845 196.450 130.278 1.00 211.71 ? 67  TRP B CZ3 1 
ATOM   1677  C CH2 . TRP B 2 45  ? 129.779 197.209 130.776 1.00 211.71 ? 67  TRP B CH2 1 
ATOM   1678  N N   . LYS B 2 46  ? 135.826 197.797 126.014 1.00 208.17 ? 68  LYS B N   1 
ATOM   1679  C CA  . LYS B 2 46  ? 136.964 197.257 125.284 1.00 208.17 ? 68  LYS B CA  1 
ATOM   1680  C C   . LYS B 2 46  ? 137.093 195.770 125.574 1.00 208.17 ? 68  LYS B C   1 
ATOM   1681  O O   . LYS B 2 46  ? 137.145 195.363 126.739 1.00 208.17 ? 68  LYS B O   1 
ATOM   1682  C CB  . LYS B 2 46  ? 138.258 197.986 125.659 1.00 208.17 ? 68  LYS B CB  1 
ATOM   1683  C CG  . LYS B 2 46  ? 138.376 199.381 125.068 1.00 208.17 ? 68  LYS B CG  1 
ATOM   1684  C CD  . LYS B 2 46  ? 139.784 199.932 125.228 1.00 208.17 ? 68  LYS B CD  1 
ATOM   1685  C CE  . LYS B 2 46  ? 139.938 201.265 124.514 1.00 208.17 ? 68  LYS B CE  1 
ATOM   1686  N NZ  . LYS B 2 46  ? 141.329 201.788 124.611 1.00 208.17 ? 68  LYS B NZ  1 
ATOM   1687  N N   . THR B 2 47  ? 137.144 194.968 124.514 1.00 204.77 ? 69  THR B N   1 
ATOM   1688  C CA  . THR B 2 47  ? 137.348 193.526 124.609 1.00 204.77 ? 69  THR B CA  1 
ATOM   1689  C C   . THR B 2 47  ? 138.688 193.202 123.960 1.00 204.77 ? 69  THR B C   1 
ATOM   1690  O O   . THR B 2 47  ? 138.815 193.252 122.732 1.00 204.77 ? 69  THR B O   1 
ATOM   1691  C CB  . THR B 2 47  ? 136.211 192.761 123.934 1.00 204.77 ? 69  THR B CB  1 
ATOM   1692  O OG1 . THR B 2 47  ? 136.127 193.142 122.555 1.00 204.77 ? 69  THR B OG1 1 
ATOM   1693  C CG2 . THR B 2 47  ? 134.887 193.060 124.619 1.00 204.77 ? 69  THR B CG2 1 
ATOM   1694  N N   . ASN B 2 48  ? 139.682 192.875 124.789 1.00 201.39 ? 70  ASN B N   1 
ATOM   1695  C CA  . ASN B 2 48  ? 141.044 192.596 124.330 1.00 201.39 ? 70  ASN B CA  1 
ATOM   1696  C C   . ASN B 2 48  ? 141.613 193.786 123.556 1.00 201.39 ? 70  ASN B C   1 
ATOM   1697  O O   . ASN B 2 48  ? 142.178 193.639 122.470 1.00 201.39 ? 70  ASN B O   1 
ATOM   1698  C CB  . ASN B 2 48  ? 141.094 191.316 123.492 1.00 201.39 ? 70  ASN B CB  1 
ATOM   1699  C CG  . ASN B 2 48  ? 142.469 190.676 123.486 1.00 201.39 ? 70  ASN B CG  1 
ATOM   1700  O OD1 . ASN B 2 48  ? 143.476 191.336 123.746 1.00 201.39 ? 70  ASN B OD1 1 
ATOM   1701  N ND2 . ASN B 2 48  ? 142.519 189.384 123.187 1.00 201.39 ? 70  ASN B ND2 1 
ATOM   1702  N N   . HIS B 2 49  ? 141.450 194.979 124.133 1.00 201.64 ? 71  HIS B N   1 
ATOM   1703  C CA  . HIS B 2 49  ? 141.966 196.223 123.557 1.00 201.64 ? 71  HIS B CA  1 
ATOM   1704  C C   . HIS B 2 49  ? 141.401 196.470 122.159 1.00 201.64 ? 71  HIS B C   1 
ATOM   1705  O O   . HIS B 2 49  ? 142.108 196.917 121.254 1.00 201.64 ? 71  HIS B O   1 
ATOM   1706  C CB  . HIS B 2 49  ? 143.496 196.231 123.536 1.00 201.64 ? 71  HIS B CB  1 
ATOM   1707  C CG  . HIS B 2 49  ? 144.120 195.929 124.863 1.00 201.64 ? 71  HIS B CG  1 
ATOM   1708  N ND1 . HIS B 2 49  ? 144.209 196.863 125.873 1.00 201.64 ? 71  HIS B ND1 1 
ATOM   1709  C CD2 . HIS B 2 49  ? 144.685 194.798 125.346 1.00 201.64 ? 71  HIS B CD2 1 
ATOM   1710  C CE1 . HIS B 2 49  ? 144.802 196.319 126.921 1.00 201.64 ? 71  HIS B CE1 1 
ATOM   1711  N NE2 . HIS B 2 49  ? 145.101 195.067 126.627 1.00 201.64 ? 71  HIS B NE2 1 
ATOM   1712  N N   . ALA B 2 50  ? 140.116 196.176 121.982 1.00 203.44 ? 72  ALA B N   1 
ATOM   1713  C CA  . ALA B 2 50  ? 139.433 196.381 120.713 1.00 203.44 ? 72  ALA B CA  1 
ATOM   1714  C C   . ALA B 2 50  ? 138.145 197.155 120.949 1.00 203.44 ? 72  ALA B C   1 
ATOM   1715  O O   . ALA B 2 50  ? 137.433 196.910 121.927 1.00 203.44 ? 72  ALA B O   1 
ATOM   1716  C CB  . ALA B 2 50  ? 139.125 195.049 120.019 1.00 203.44 ? 72  ALA B CB  1 
ATOM   1717  N N   . ALA B 2 51  ? 137.852 198.089 120.048 1.00 201.08 ? 73  ALA B N   1 
ATOM   1718  C CA  . ALA B 2 51  ? 136.644 198.892 120.168 1.00 201.08 ? 73  ALA B CA  1 
ATOM   1719  C C   . ALA B 2 51  ? 135.421 198.063 119.798 1.00 201.08 ? 73  ALA B C   1 
ATOM   1720  O O   . ALA B 2 51  ? 135.413 197.367 118.778 1.00 201.08 ? 73  ALA B O   1 
ATOM   1721  C CB  . ALA B 2 51  ? 136.737 200.129 119.277 1.00 201.08 ? 73  ALA B CB  1 
ATOM   1722  N N   . VAL B 2 52  ? 134.387 198.138 120.630 1.00 198.79 ? 74  VAL B N   1 
ATOM   1723  C CA  . VAL B 2 52  ? 133.155 197.386 120.406 1.00 198.79 ? 74  VAL B CA  1 
ATOM   1724  C C   . VAL B 2 52  ? 132.173 198.259 119.631 1.00 198.79 ? 74  VAL B C   1 
ATOM   1725  O O   . VAL B 2 52  ? 132.228 199.493 119.732 1.00 198.79 ? 74  VAL B O   1 
ATOM   1726  C CB  . VAL B 2 52  ? 132.551 196.900 121.734 1.00 198.79 ? 74  VAL B CB  1 
ATOM   1727  C CG1 . VAL B 2 52  ? 133.592 196.138 122.539 1.00 198.79 ? 74  VAL B CG1 1 
ATOM   1728  C CG2 . VAL B 2 52  ? 132.006 198.072 122.538 1.00 198.79 ? 74  VAL B CG2 1 
ATOM   1729  N N   . PRO B 2 53  ? 131.282 197.674 118.835 1.00 196.57 ? 75  PRO B N   1 
ATOM   1730  C CA  . PRO B 2 53  ? 130.301 198.484 118.106 1.00 196.57 ? 75  PRO B CA  1 
ATOM   1731  C C   . PRO B 2 53  ? 129.284 199.111 119.047 1.00 196.57 ? 75  PRO B C   1 
ATOM   1732  O O   . PRO B 2 53  ? 129.043 198.639 120.160 1.00 196.57 ? 75  PRO B O   1 
ATOM   1733  C CB  . PRO B 2 53  ? 129.633 197.479 117.160 1.00 196.57 ? 75  PRO B CB  1 
ATOM   1734  C CG  . PRO B 2 53  ? 130.561 196.303 117.114 1.00 196.57 ? 75  PRO B CG  1 
ATOM   1735  C CD  . PRO B 2 53  ? 131.212 196.253 118.458 1.00 196.57 ? 75  PRO B CD  1 
ATOM   1736  N N   . ARG B 2 54  ? 128.681 200.202 118.575 1.00 190.12 ? 76  ARG B N   1 
ATOM   1737  C CA  . ARG B 2 54  ? 127.683 200.922 119.355 1.00 190.12 ? 76  ARG B CA  1 
ATOM   1738  C C   . ARG B 2 54  ? 126.310 200.265 119.321 1.00 190.12 ? 76  ARG B C   1 
ATOM   1739  O O   . ARG B 2 54  ? 125.433 200.664 120.095 1.00 190.12 ? 76  ARG B O   1 
ATOM   1740  C CB  . ARG B 2 54  ? 127.570 202.365 118.858 1.00 190.12 ? 76  ARG B CB  1 
ATOM   1741  C CG  . ARG B 2 54  ? 128.779 203.229 119.175 1.00 190.12 ? 76  ARG B CG  1 
ATOM   1742  C CD  . ARG B 2 54  ? 128.519 204.686 118.831 1.00 190.12 ? 76  ARG B CD  1 
ATOM   1743  N NE  . ARG B 2 54  ? 129.615 205.552 119.253 1.00 190.12 ? 76  ARG B NE  1 
ATOM   1744  C CZ  . ARG B 2 54  ? 129.595 206.878 119.163 1.00 190.12 ? 76  ARG B CZ  1 
ATOM   1745  N NH1 . ARG B 2 54  ? 128.533 207.495 118.665 1.00 190.12 ? 76  ARG B NH1 1 
ATOM   1746  N NH2 . ARG B 2 54  ? 130.638 207.588 119.572 1.00 190.12 ? 76  ARG B NH2 1 
ATOM   1747  N N   . GLU B 2 55  ? 126.100 199.276 118.449 1.00 190.48 ? 77  GLU B N   1 
ATOM   1748  C CA  . GLU B 2 55  ? 124.797 198.623 118.374 1.00 190.48 ? 77  GLU B CA  1 
ATOM   1749  C C   . GLU B 2 55  ? 124.530 197.776 119.613 1.00 190.48 ? 77  GLU B C   1 
ATOM   1750  O O   . GLU B 2 55  ? 123.406 197.755 120.127 1.00 190.48 ? 77  GLU B O   1 
ATOM   1751  C CB  . GLU B 2 55  ? 124.713 197.769 117.109 1.00 190.48 ? 77  GLU B CB  1 
ATOM   1752  C CG  . GLU B 2 55  ? 123.476 196.888 117.030 1.00 190.48 ? 77  GLU B CG  1 
ATOM   1753  C CD  . GLU B 2 55  ? 123.394 196.113 115.730 1.00 190.48 ? 77  GLU B CD  1 
ATOM   1754  O OE1 . GLU B 2 55  ? 123.749 196.680 114.675 1.00 190.48 ? 77  GLU B OE1 1 
ATOM   1755  O OE2 . GLU B 2 55  ? 122.975 194.937 115.762 1.00 190.48 ? 77  GLU B OE2 1 
ATOM   1756  N N   . GLN B 2 56  ? 125.550 197.079 120.110 1.00 192.74 ? 78  GLN B N   1 
ATOM   1757  C CA  . GLN B 2 56  ? 125.398 196.220 121.276 1.00 192.74 ? 78  GLN B CA  1 
ATOM   1758  C C   . GLN B 2 56  ? 125.530 196.973 122.593 1.00 192.74 ? 78  GLN B C   1 
ATOM   1759  O O   . GLN B 2 56  ? 125.271 196.386 123.649 1.00 192.74 ? 78  GLN B O   1 
ATOM   1760  C CB  . GLN B 2 56  ? 126.426 195.086 121.227 1.00 192.74 ? 78  GLN B CB  1 
ATOM   1761  C CG  . GLN B 2 56  ? 127.869 195.558 121.153 1.00 192.74 ? 78  GLN B CG  1 
ATOM   1762  C CD  . GLN B 2 56  ? 128.835 194.431 120.844 1.00 192.74 ? 78  GLN B CD  1 
ATOM   1763  O OE1 . GLN B 2 56  ? 128.446 193.395 120.306 1.00 192.74 ? 78  GLN B OE1 1 
ATOM   1764  N NE2 . GLN B 2 56  ? 130.103 194.628 121.184 1.00 192.74 ? 78  GLN B NE2 1 
ATOM   1765  N N   . VAL B 2 57  ? 125.916 198.244 122.562 1.00 195.16 ? 79  VAL B N   1 
ATOM   1766  C CA  . VAL B 2 57  ? 126.066 199.044 123.772 1.00 195.16 ? 79  VAL B CA  1 
ATOM   1767  C C   . VAL B 2 57  ? 124.758 199.780 124.029 1.00 195.16 ? 79  VAL B C   1 
ATOM   1768  O O   . VAL B 2 57  ? 124.262 200.505 123.160 1.00 195.16 ? 79  VAL B O   1 
ATOM   1769  C CB  . VAL B 2 57  ? 127.238 200.029 123.647 1.00 195.16 ? 79  VAL B CB  1 
ATOM   1770  C CG1 . VAL B 2 57  ? 127.370 200.859 124.915 1.00 195.16 ? 79  VAL B CG1 1 
ATOM   1771  C CG2 . VAL B 2 57  ? 128.530 199.283 123.355 1.00 195.16 ? 79  VAL B CG2 1 
ATOM   1772  N N   . THR B 2 58  ? 124.200 199.596 125.223 1.00 203.83 ? 80  THR B N   1 
ATOM   1773  C CA  . THR B 2 58  ? 122.947 200.235 125.601 1.00 203.83 ? 80  THR B CA  1 
ATOM   1774  C C   . THR B 2 58  ? 123.027 200.665 127.057 1.00 203.83 ? 80  THR B C   1 
ATOM   1775  O O   . THR B 2 58  ? 123.474 199.893 127.911 1.00 203.83 ? 80  THR B O   1 
ATOM   1776  C CB  . THR B 2 58  ? 121.754 199.295 125.393 1.00 203.83 ? 80  THR B CB  1 
ATOM   1777  O OG1 . THR B 2 58  ? 121.814 198.727 124.079 1.00 203.83 ? 80  THR B OG1 1 
ATOM   1778  C CG2 . THR B 2 58  ? 120.444 200.051 125.552 1.00 203.83 ? 80  THR B CG2 1 
ATOM   1779  N N   . VAL B 2 59  ? 122.594 201.890 127.334 1.00 216.78 ? 81  VAL B N   1 
ATOM   1780  C CA  . VAL B 2 59  ? 122.588 202.440 128.684 1.00 216.78 ? 81  VAL B CA  1 
ATOM   1781  C C   . VAL B 2 59  ? 121.178 202.330 129.247 1.00 216.78 ? 81  VAL B C   1 
ATOM   1782  O O   . VAL B 2 59  ? 120.190 202.531 128.528 1.00 216.78 ? 81  VAL B O   1 
ATOM   1783  C CB  . VAL B 2 59  ? 123.091 203.898 128.688 1.00 216.78 ? 81  VAL B CB  1 
ATOM   1784  C CG1 . VAL B 2 59  ? 122.206 204.785 127.820 1.00 216.78 ? 81  VAL B CG1 1 
ATOM   1785  C CG2 . VAL B 2 59  ? 123.176 204.436 130.104 1.00 216.78 ? 81  VAL B CG2 1 
ATOM   1786  N N   . ILE B 2 60  ? 121.079 201.989 130.529 1.00 229.36 ? 82  ILE B N   1 
ATOM   1787  C CA  . ILE B 2 60  ? 119.799 201.790 131.199 1.00 229.36 ? 82  ILE B CA  1 
ATOM   1788  C C   . ILE B 2 60  ? 119.503 202.916 132.188 1.00 229.36 ? 82  ILE B C   1 
ATOM   1789  O O   . ILE B 2 60  ? 118.386 203.432 132.234 1.00 229.36 ? 82  ILE B O   1 
ATOM   1790  C CB  . ILE B 2 60  ? 119.738 200.405 131.886 1.00 229.36 ? 82  ILE B CB  1 
ATOM   1791  C CG1 . ILE B 2 60  ? 118.344 200.152 132.466 1.00 229.36 ? 82  ILE B CG1 1 
ATOM   1792  C CG2 . ILE B 2 60  ? 120.837 200.243 132.936 1.00 229.36 ? 82  ILE B CG2 1 
ATOM   1793  C CD1 . ILE B 2 60  ? 118.103 198.714 132.873 1.00 229.36 ? 82  ILE B CD1 1 
ATOM   1794  N N   . ASN B 2 61  ? 120.496 203.314 132.983 1.00 232.36 ? 83  ASN B N   1 
ATOM   1795  C CA  . ASN B 2 61  ? 120.306 204.387 133.950 1.00 232.36 ? 83  ASN B CA  1 
ATOM   1796  C C   . ASN B 2 61  ? 121.481 205.355 133.915 1.00 232.36 ? 83  ASN B C   1 
ATOM   1797  O O   . ASN B 2 61  ? 122.366 205.235 133.062 1.00 232.36 ? 83  ASN B O   1 
ATOM   1798  C CB  . ASN B 2 61  ? 120.114 203.818 135.358 1.00 232.36 ? 83  ASN B CB  1 
ATOM   1799  C CG  . ASN B 2 61  ? 118.668 203.451 135.645 1.00 232.36 ? 83  ASN B CG  1 
ATOM   1800  O OD1 . ASN B 2 61  ? 117.757 203.923 134.965 1.00 232.36 ? 83  ASN B OD1 1 
ATOM   1801  N ND2 . ASN B 2 61  ? 118.448 202.611 136.653 1.00 232.36 ? 83  ASN B ND2 1 
ATOM   1802  N N   . ARG B 2 62  ? 121.499 206.317 134.840 1.00 230.92 ? 84  ARG B N   1 
ATOM   1803  C CA  . ARG B 2 62  ? 122.541 207.337 134.824 1.00 230.92 ? 84  ARG B CA  1 
ATOM   1804  C C   . ARG B 2 62  ? 123.912 206.757 135.146 1.00 230.92 ? 84  ARG B C   1 
ATOM   1805  O O   . ARG B 2 62  ? 124.928 207.270 134.663 1.00 230.92 ? 84  ARG B O   1 
ATOM   1806  C CB  . ARG B 2 62  ? 122.194 208.454 135.809 1.00 230.92 ? 84  ARG B CB  1 
ATOM   1807  C CG  . ARG B 2 62  ? 123.109 209.665 135.722 1.00 230.92 ? 84  ARG B CG  1 
ATOM   1808  C CD  . ARG B 2 62  ? 122.883 210.618 136.885 1.00 230.92 ? 84  ARG B CD  1 
ATOM   1809  N NE  . ARG B 2 62  ? 123.743 211.795 136.799 1.00 230.92 ? 84  ARG B NE  1 
ATOM   1810  C CZ  . ARG B 2 62  ? 123.807 212.743 137.727 1.00 230.92 ? 84  ARG B CZ  1 
ATOM   1811  N NH1 . ARG B 2 62  ? 123.062 212.657 138.820 1.00 230.92 ? 84  ARG B NH1 1 
ATOM   1812  N NH2 . ARG B 2 62  ? 124.619 213.779 137.563 1.00 230.92 ? 84  ARG B NH2 1 
ATOM   1813  N N   . THR B 2 63  ? 123.967 205.691 135.945 1.00 228.70 ? 85  THR B N   1 
ATOM   1814  C CA  . THR B 2 63  ? 125.233 205.131 136.403 1.00 228.70 ? 85  THR B CA  1 
ATOM   1815  C C   . THR B 2 63  ? 125.389 203.657 136.041 1.00 228.70 ? 85  THR B C   1 
ATOM   1816  O O   . THR B 2 63  ? 126.159 202.943 136.690 1.00 228.70 ? 85  THR B O   1 
ATOM   1817  C CB  . THR B 2 63  ? 125.382 205.323 137.914 1.00 228.70 ? 85  THR B CB  1 
ATOM   1818  O OG1 . THR B 2 63  ? 126.660 204.831 138.337 1.00 228.70 ? 85  THR B OG1 1 
ATOM   1819  C CG2 . THR B 2 63  ? 124.278 204.586 138.663 1.00 228.70 ? 85  THR B CG2 1 
ATOM   1820  N N   . THR B 2 64  ? 124.685 203.184 135.014 1.00 227.22 ? 86  THR B N   1 
ATOM   1821  C CA  . THR B 2 64  ? 124.780 201.785 134.619 1.00 227.22 ? 86  THR B CA  1 
ATOM   1822  C C   . THR B 2 64  ? 124.642 201.669 133.109 1.00 227.22 ? 86  THR B C   1 
ATOM   1823  O O   . THR B 2 64  ? 123.738 202.266 132.518 1.00 227.22 ? 86  THR B O   1 
ATOM   1824  C CB  . THR B 2 64  ? 123.707 200.936 135.311 1.00 227.22 ? 86  THR B CB  1 
ATOM   1825  O OG1 . THR B 2 64  ? 123.618 201.301 136.694 1.00 227.22 ? 86  THR B OG1 1 
ATOM   1826  C CG2 . THR B 2 64  ? 124.051 199.457 135.204 1.00 227.22 ? 86  THR B CG2 1 
ATOM   1827  N N   . SER B 2 65  ? 125.538 200.897 132.497 1.00 213.20 ? 87  SER B N   1 
ATOM   1828  C CA  . SER B 2 65  ? 125.502 200.618 131.070 1.00 213.20 ? 87  SER B CA  1 
ATOM   1829  C C   . SER B 2 65  ? 125.686 199.124 130.849 1.00 213.20 ? 87  SER B C   1 
ATOM   1830  O O   . SER B 2 65  ? 126.375 198.447 131.618 1.00 213.20 ? 87  SER B O   1 
ATOM   1831  C CB  . SER B 2 65  ? 126.585 201.399 130.313 1.00 213.20 ? 87  SER B CB  1 
ATOM   1832  O OG  . SER B 2 65  ? 127.823 201.350 131.000 1.00 213.20 ? 87  SER B OG  1 
ATOM   1833  N N   . SER B 2 66  ? 125.065 198.612 129.788 1.00 202.65 ? 88  SER B N   1 
ATOM   1834  C CA  . SER B 2 66  ? 125.065 197.185 129.505 1.00 202.65 ? 88  SER B CA  1 
ATOM   1835  C C   . SER B 2 66  ? 125.437 196.933 128.051 1.00 202.65 ? 88  SER B C   1 
ATOM   1836  O O   . SER B 2 66  ? 125.117 197.725 127.161 1.00 202.65 ? 88  SER B O   1 
ATOM   1837  C CB  . SER B 2 66  ? 123.697 196.556 129.803 1.00 202.65 ? 88  SER B CB  1 
ATOM   1838  O OG  . SER B 2 66  ? 123.549 196.287 131.185 1.00 202.65 ? 88  SER B OG  1 
ATOM   1839  N N   . VAL B 2 67  ? 126.122 195.813 127.823 1.00 196.14 ? 89  VAL B N   1 
ATOM   1840  C CA  . VAL B 2 67  ? 126.469 195.349 126.487 1.00 196.14 ? 89  VAL B CA  1 
ATOM   1841  C C   . VAL B 2 67  ? 126.071 193.885 126.370 1.00 196.14 ? 89  VAL B C   1 
ATOM   1842  O O   . VAL B 2 67  ? 125.963 193.170 127.371 1.00 196.14 ? 89  VAL B O   1 
ATOM   1843  C CB  . VAL B 2 67  ? 127.970 195.534 126.170 1.00 196.14 ? 89  VAL B CB  1 
ATOM   1844  C CG1 . VAL B 2 67  ? 128.371 196.992 126.317 1.00 196.14 ? 89  VAL B CG1 1 
ATOM   1845  C CG2 . VAL B 2 67  ? 128.817 194.652 127.074 1.00 196.14 ? 89  VAL B CG2 1 
ATOM   1846  N N   . THR B 2 68  ? 125.846 193.442 125.136 1.00 186.48 ? 90  THR B N   1 
ATOM   1847  C CA  . THR B 2 68  ? 125.399 192.085 124.867 1.00 186.48 ? 90  THR B CA  1 
ATOM   1848  C C   . THR B 2 68  ? 126.393 191.367 123.963 1.00 186.48 ? 90  THR B C   1 
ATOM   1849  O O   . THR B 2 68  ? 127.149 191.989 123.210 1.00 186.48 ? 90  THR B O   1 
ATOM   1850  C CB  . THR B 2 68  ? 124.007 192.072 124.219 1.00 186.48 ? 90  THR B CB  1 
ATOM   1851  O OG1 . THR B 2 68  ? 123.634 190.724 123.909 1.00 186.48 ? 90  THR B OG1 1 
ATOM   1852  C CG2 . THR B 2 68  ? 124.003 192.901 122.945 1.00 186.48 ? 90  THR B CG2 1 
ATOM   1853  N N   . PHE B 2 69  ? 126.383 190.039 124.054 1.00 179.23 ? 91  PHE B N   1 
ATOM   1854  C CA  . PHE B 2 69  ? 127.221 189.183 123.228 1.00 179.23 ? 91  PHE B CA  1 
ATOM   1855  C C   . PHE B 2 69  ? 126.424 187.951 122.830 1.00 179.23 ? 91  PHE B C   1 
ATOM   1856  O O   . PHE B 2 69  ? 125.734 187.355 123.662 1.00 179.23 ? 91  PHE B O   1 
ATOM   1857  C CB  . PHE B 2 69  ? 128.502 188.766 123.962 1.00 179.23 ? 91  PHE B CB  1 
ATOM   1858  C CG  . PHE B 2 69  ? 129.400 189.916 124.317 1.00 179.23 ? 91  PHE B CG  1 
ATOM   1859  C CD1 . PHE B 2 69  ? 130.309 190.412 123.398 1.00 179.23 ? 91  PHE B CD1 1 
ATOM   1860  C CD2 . PHE B 2 69  ? 129.339 190.497 125.572 1.00 179.23 ? 91  PHE B CD2 1 
ATOM   1861  C CE1 . PHE B 2 69  ? 131.138 191.469 123.723 1.00 179.23 ? 91  PHE B CE1 1 
ATOM   1862  C CE2 . PHE B 2 69  ? 130.165 191.554 125.903 1.00 179.23 ? 91  PHE B CE2 1 
ATOM   1863  C CZ  . PHE B 2 69  ? 131.066 192.040 124.977 1.00 179.23 ? 91  PHE B CZ  1 
ATOM   1864  N N   . THR B 2 70  ? 126.521 187.574 121.558 1.00 179.58 ? 92  THR B N   1 
ATOM   1865  C CA  . THR B 2 70  ? 125.782 186.442 121.012 1.00 179.58 ? 92  THR B CA  1 
ATOM   1866  C C   . THR B 2 70  ? 126.766 185.385 120.531 1.00 179.58 ? 92  THR B C   1 
ATOM   1867  O O   . THR B 2 70  ? 127.524 185.626 119.585 1.00 179.58 ? 92  THR B O   1 
ATOM   1868  C CB  . THR B 2 70  ? 124.869 186.880 119.864 1.00 179.58 ? 92  THR B CB  1 
ATOM   1869  O OG1 . THR B 2 70  ? 123.831 187.727 120.373 1.00 179.58 ? 92  THR B OG1 1 
ATOM   1870  C CG2 . THR B 2 70  ? 124.244 185.668 119.189 1.00 179.58 ? 92  THR B CG2 1 
ATOM   1871  N N   . ASP B 2 71  ? 126.749 184.222 121.184 1.00 162.35 ? 93  ASP B N   1 
ATOM   1872  C CA  . ASP B 2 71  ? 127.544 183.061 120.781 1.00 162.35 ? 93  ASP B CA  1 
ATOM   1873  C C   . ASP B 2 71  ? 129.037 183.395 120.739 1.00 162.35 ? 93  ASP B C   1 
ATOM   1874  O O   . ASP B 2 71  ? 129.680 183.379 119.688 1.00 162.35 ? 93  ASP B O   1 
ATOM   1875  C CB  . ASP B 2 71  ? 127.060 182.513 119.433 1.00 162.35 ? 93  ASP B CB  1 
ATOM   1876  C CG  . ASP B 2 71  ? 127.593 181.124 119.143 1.00 162.35 ? 93  ASP B CG  1 
ATOM   1877  O OD1 . ASP B 2 71  ? 128.251 180.538 120.029 1.00 162.35 ? 93  ASP B OD1 1 
ATOM   1878  O OD2 . ASP B 2 71  ? 127.352 180.616 118.028 1.00 162.35 ? 93  ASP B OD2 1 
ATOM   1879  N N   . VAL B 2 72  ? 129.581 183.707 121.917 1.00 147.75 ? 94  VAL B N   1 
ATOM   1880  C CA  . VAL B 2 72  ? 131.009 183.976 122.030 1.00 147.75 ? 94  VAL B CA  1 
ATOM   1881  C C   . VAL B 2 72  ? 131.792 182.700 121.746 1.00 147.75 ? 94  VAL B C   1 
ATOM   1882  O O   . VAL B 2 72  ? 131.411 181.602 122.174 1.00 147.75 ? 94  VAL B O   1 
ATOM   1883  C CB  . VAL B 2 72  ? 131.339 184.549 123.420 1.00 147.75 ? 94  VAL B CB  1 
ATOM   1884  C CG1 . VAL B 2 72  ? 130.921 183.582 124.520 1.00 147.75 ? 94  VAL B CG1 1 
ATOM   1885  C CG2 . VAL B 2 72  ? 132.821 184.881 123.526 1.00 147.75 ? 94  VAL B CG2 1 
ATOM   1886  N N   . VAL B 2 73  ? 132.887 182.837 120.998 1.00 140.52 ? 95  VAL B N   1 
ATOM   1887  C CA  . VAL B 2 73  ? 133.705 181.692 120.613 1.00 140.52 ? 95  VAL B CA  1 
ATOM   1888  C C   . VAL B 2 73  ? 135.083 181.819 121.248 1.00 140.52 ? 95  VAL B C   1 
ATOM   1889  O O   . VAL B 2 73  ? 135.749 180.814 121.523 1.00 140.52 ? 95  VAL B O   1 
ATOM   1890  C CB  . VAL B 2 73  ? 133.811 181.574 119.081 1.00 140.52 ? 95  VAL B CB  1 
ATOM   1891  C CG1 . VAL B 2 73  ? 134.388 180.222 118.688 1.00 140.52 ? 95  VAL B CG1 1 
ATOM   1892  C CG2 . VAL B 2 73  ? 132.450 181.786 118.436 1.00 140.52 ? 95  VAL B CG2 1 
ATOM   1893  N N   . LEU B 2 74  ? 135.514 183.049 121.488 1.00 141.17 ? 96  LEU B N   1 
ATOM   1894  C CA  . LEU B 2 74  ? 136.825 183.276 122.083 1.00 141.17 ? 96  LEU B CA  1 
ATOM   1895  C C   . LEU B 2 74  ? 136.819 182.812 123.536 1.00 141.17 ? 96  LEU B C   1 
ATOM   1896  O O   . LEU B 2 74  ? 135.960 183.241 124.314 1.00 141.17 ? 96  LEU B O   1 
ATOM   1897  C CB  . LEU B 2 74  ? 137.201 184.753 121.988 1.00 141.17 ? 96  LEU B CB  1 
ATOM   1898  C CG  . LEU B 2 74  ? 138.461 185.212 122.721 1.00 141.17 ? 96  LEU B CG  1 
ATOM   1899  C CD1 . LEU B 2 74  ? 139.699 184.901 121.896 1.00 141.17 ? 96  LEU B CD1 1 
ATOM   1900  C CD2 . LEU B 2 74  ? 138.379 186.700 123.016 1.00 141.17 ? 96  LEU B CD2 1 
ATOM   1901  N N   . PRO B 2 75  ? 137.746 181.938 123.937 1.00 136.18 ? 97  PRO B N   1 
ATOM   1902  C CA  . PRO B 2 75  ? 137.682 181.400 125.306 1.00 136.18 ? 97  PRO B CA  1 
ATOM   1903  C C   . PRO B 2 75  ? 138.048 182.413 126.375 1.00 136.18 ? 97  PRO B C   1 
ATOM   1904  O O   . PRO B 2 75  ? 137.378 182.474 127.414 1.00 136.18 ? 97  PRO B O   1 
ATOM   1905  C CB  . PRO B 2 75  ? 138.672 180.228 125.264 1.00 136.18 ? 97  PRO B CB  1 
ATOM   1906  C CG  . PRO B 2 75  ? 139.632 180.587 124.181 1.00 136.18 ? 97  PRO B CG  1 
ATOM   1907  C CD  . PRO B 2 75  ? 138.842 181.345 123.152 1.00 136.18 ? 97  PRO B CD  1 
ATOM   1908  N N   . SER B 2 76  ? 139.088 183.212 126.159 1.00 145.14 ? 98  SER B N   1 
ATOM   1909  C CA  . SER B 2 76  ? 139.557 184.185 127.144 1.00 145.14 ? 98  SER B CA  1 
ATOM   1910  C C   . SER B 2 76  ? 139.211 185.582 126.639 1.00 145.14 ? 98  SER B C   1 
ATOM   1911  O O   . SER B 2 76  ? 139.908 186.133 125.783 1.00 145.14 ? 98  SER B O   1 
ATOM   1912  C CB  . SER B 2 76  ? 141.055 184.033 127.387 1.00 145.14 ? 98  SER B CB  1 
ATOM   1913  O OG  . SER B 2 76  ? 141.328 182.892 128.182 1.00 145.14 ? 98  SER B OG  1 
ATOM   1914  N N   . VAL B 2 77  ? 138.139 186.154 127.180 1.00 156.17 ? 99  VAL B N   1 
ATOM   1915  C CA  . VAL B 2 77  ? 137.662 187.477 126.794 1.00 156.17 ? 99  VAL B CA  1 
ATOM   1916  C C   . VAL B 2 77  ? 137.936 188.434 127.945 1.00 156.17 ? 99  VAL B C   1 
ATOM   1917  O O   . VAL B 2 77  ? 137.397 188.265 129.046 1.00 156.17 ? 99  VAL B O   1 
ATOM   1918  C CB  . VAL B 2 77  ? 136.168 187.460 126.439 1.00 156.17 ? 99  VAL B CB  1 
ATOM   1919  C CG1 . VAL B 2 77  ? 135.781 188.738 125.711 1.00 156.17 ? 99  VAL B CG1 1 
ATOM   1920  C CG2 . VAL B 2 77  ? 135.836 186.238 125.600 1.00 156.17 ? 99  VAL B CG2 1 
ATOM   1921  N N   . GLN B 2 78  ? 138.772 189.438 127.692 1.00 174.97 ? 100 GLN B N   1 
ATOM   1922  C CA  . GLN B 2 78  ? 139.098 190.457 128.688 1.00 174.97 ? 100 GLN B CA  1 
ATOM   1923  C C   . GLN B 2 78  ? 138.143 191.628 128.498 1.00 174.97 ? 100 GLN B C   1 
ATOM   1924  O O   . GLN B 2 78  ? 138.322 192.453 127.599 1.00 174.97 ? 100 GLN B O   1 
ATOM   1925  C CB  . GLN B 2 78  ? 140.554 190.891 128.558 1.00 174.97 ? 100 GLN B CB  1 
ATOM   1926  C CG  . GLN B 2 78  ? 141.555 189.775 128.801 1.00 174.97 ? 100 GLN B CG  1 
ATOM   1927  C CD  . GLN B 2 78  ? 142.990 190.256 128.731 1.00 174.97 ? 100 GLN B CD  1 
ATOM   1928  O OE1 . GLN B 2 78  ? 143.255 191.407 128.385 1.00 174.97 ? 100 GLN B OE1 1 
ATOM   1929  N NE2 . GLN B 2 78  ? 143.927 189.374 129.059 1.00 174.97 ? 100 GLN B NE2 1 
ATOM   1930  N N   . LEU B 2 79  ? 137.122 191.702 129.347 1.00 191.74 ? 101 LEU B N   1 
ATOM   1931  C CA  . LEU B 2 79  ? 136.107 192.744 129.271 1.00 191.74 ? 101 LEU B CA  1 
ATOM   1932  C C   . LEU B 2 79  ? 136.495 193.880 130.210 1.00 191.74 ? 101 LEU B C   1 
ATOM   1933  O O   . LEU B 2 79  ? 136.646 193.668 131.418 1.00 191.74 ? 101 LEU B O   1 
ATOM   1934  C CB  . LEU B 2 79  ? 134.728 192.181 129.621 1.00 191.74 ? 101 LEU B CB  1 
ATOM   1935  C CG  . LEU B 2 79  ? 133.521 193.114 129.764 1.00 191.74 ? 101 LEU B CG  1 
ATOM   1936  C CD1 . LEU B 2 79  ? 132.258 192.391 129.327 1.00 191.74 ? 101 LEU B CD1 1 
ATOM   1937  C CD2 . LEU B 2 79  ? 133.359 193.609 131.194 1.00 191.74 ? 101 LEU B CD2 1 
ATOM   1938  N N   . THR B 2 80  ? 136.659 195.079 129.653 1.00 207.57 ? 102 THR B N   1 
ATOM   1939  C CA  . THR B 2 80  ? 137.032 196.261 130.418 1.00 207.57 ? 102 THR B CA  1 
ATOM   1940  C C   . THR B 2 80  ? 136.096 197.405 130.060 1.00 207.57 ? 102 THR B C   1 
ATOM   1941  O O   . THR B 2 80  ? 135.878 197.685 128.877 1.00 207.57 ? 102 THR B O   1 
ATOM   1942  C CB  . THR B 2 80  ? 138.484 196.673 130.143 1.00 207.57 ? 102 THR B CB  1 
ATOM   1943  O OG1 . THR B 2 80  ? 138.653 196.929 128.743 1.00 207.57 ? 102 THR B OG1 1 
ATOM   1944  C CG2 . THR B 2 80  ? 139.449 195.577 130.574 1.00 207.57 ? 102 THR B CG2 1 
ATOM   1945  N N   . CYS B 2 81  ? 135.549 198.063 131.079 1.00 215.86 ? 103 CYS B N   1 
ATOM   1946  C CA  . CYS B 2 81  ? 134.704 199.236 130.892 1.00 215.86 ? 103 CYS B CA  1 
ATOM   1947  C C   . CYS B 2 81  ? 135.523 200.483 131.205 1.00 215.86 ? 103 CYS B C   1 
ATOM   1948  O O   . CYS B 2 81  ? 136.011 200.646 132.328 1.00 215.86 ? 103 CYS B O   1 
ATOM   1949  C CB  . CYS B 2 81  ? 133.453 199.164 131.770 1.00 215.86 ? 103 CYS B CB  1 
ATOM   1950  S SG  . CYS B 2 81  ? 133.750 198.974 133.547 1.00 215.86 ? 103 CYS B SG  1 
ATOM   1951  N N   . ASN B 2 82  ? 135.681 201.351 130.209 1.00 228.81 ? 104 ASN B N   1 
ATOM   1952  C CA  . ASN B 2 82  ? 136.491 202.553 130.339 1.00 228.81 ? 104 ASN B CA  1 
ATOM   1953  C C   . ASN B 2 82  ? 135.679 203.765 129.911 1.00 228.81 ? 104 ASN B C   1 
ATOM   1954  O O   . ASN B 2 82  ? 134.894 203.693 128.961 1.00 228.81 ? 104 ASN B O   1 
ATOM   1955  C CB  . ASN B 2 82  ? 137.770 202.458 129.497 1.00 228.81 ? 104 ASN B CB  1 
ATOM   1956  C CG  . ASN B 2 82  ? 138.595 201.229 129.824 1.00 228.81 ? 104 ASN B CG  1 
ATOM   1957  O OD1 . ASN B 2 82  ? 138.572 200.732 130.950 1.00 228.81 ? 104 ASN B OD1 1 
ATOM   1958  N ND2 . ASN B 2 82  ? 139.332 200.732 128.837 1.00 228.81 ? 104 ASN B ND2 1 
ATOM   1959  N N   . ILE B 2 83  ? 135.874 204.875 130.614 1.00 245.17 ? 105 ILE B N   1 
ATOM   1960  C CA  . ILE B 2 83  ? 135.176 206.121 130.327 1.00 245.17 ? 105 ILE B CA  1 
ATOM   1961  C C   . ILE B 2 83  ? 136.122 207.060 129.594 1.00 245.17 ? 105 ILE B C   1 
ATOM   1962  O O   . ILE B 2 83  ? 137.349 206.977 129.729 1.00 245.17 ? 105 ILE B O   1 
ATOM   1963  C CB  . ILE B 2 83  ? 134.631 206.774 131.615 1.00 245.17 ? 105 ILE B CB  1 
ATOM   1964  C CG1 . ILE B 2 83  ? 135.781 207.151 132.552 1.00 245.17 ? 105 ILE B CG1 1 
ATOM   1965  C CG2 . ILE B 2 83  ? 133.652 205.841 132.312 1.00 245.17 ? 105 ILE B CG2 1 
ATOM   1966  C CD1 . ILE B 2 83  ? 135.330 207.804 133.840 1.00 245.17 ? 105 ILE B CD1 1 
ATOM   1967  N N   . LEU B 2 84  ? 135.545 207.962 128.804 1.00 255.90 ? 106 LEU B N   1 
ATOM   1968  C CA  . LEU B 2 84  ? 136.305 208.943 128.038 1.00 255.90 ? 106 LEU B CA  1 
ATOM   1969  C C   . LEU B 2 84  ? 136.149 210.305 128.705 1.00 255.90 ? 106 LEU B C   1 
ATOM   1970  O O   . LEU B 2 84  ? 135.060 210.889 128.695 1.00 255.90 ? 106 LEU B O   1 
ATOM   1971  C CB  . LEU B 2 84  ? 135.833 208.984 126.586 1.00 255.90 ? 106 LEU B CB  1 
ATOM   1972  C CG  . LEU B 2 84  ? 136.641 209.875 125.640 1.00 255.90 ? 106 LEU B CG  1 
ATOM   1973  C CD1 . LEU B 2 84  ? 138.093 209.431 125.597 1.00 255.90 ? 106 LEU B CD1 1 
ATOM   1974  C CD2 . LEU B 2 84  ? 136.033 209.868 124.247 1.00 255.90 ? 106 LEU B CD2 1 
ATOM   1975  N N   . SER B 2 85  ? 137.237 210.809 129.281 1.00 261.55 ? 107 SER B N   1 
ATOM   1976  C CA  . SER B 2 85  ? 137.222 212.100 129.955 1.00 261.55 ? 107 SER B CA  1 
ATOM   1977  C C   . SER B 2 85  ? 137.384 213.217 128.925 1.00 261.55 ? 107 SER B C   1 
ATOM   1978  O O   . SER B 2 85  ? 137.376 212.987 127.713 1.00 261.55 ? 107 SER B O   1 
ATOM   1979  C CB  . SER B 2 85  ? 138.306 212.146 131.028 1.00 261.55 ? 107 SER B CB  1 
ATOM   1980  O OG  . SER B 2 85  ? 139.596 212.021 130.455 1.00 261.55 ? 107 SER B OG  1 
ATOM   1981  N N   . PHE B 2 86  ? 137.534 214.449 129.404 1.00 261.48 ? 108 PHE B N   1 
ATOM   1982  C CA  . PHE B 2 86  ? 137.711 215.582 128.509 1.00 261.48 ? 108 PHE B CA  1 
ATOM   1983  C C   . PHE B 2 86  ? 139.084 215.535 127.847 1.00 261.48 ? 108 PHE B C   1 
ATOM   1984  O O   . PHE B 2 86  ? 140.068 215.075 128.433 1.00 261.48 ? 108 PHE B O   1 
ATOM   1985  C CB  . PHE B 2 86  ? 137.541 216.897 129.270 1.00 261.48 ? 108 PHE B CB  1 
ATOM   1986  C CG  . PHE B 2 86  ? 136.107 217.302 129.465 1.00 261.48 ? 108 PHE B CG  1 
ATOM   1987  C CD1 . PHE B 2 86  ? 135.527 218.257 128.648 1.00 261.48 ? 108 PHE B CD1 1 
ATOM   1988  C CD2 . PHE B 2 86  ? 135.341 216.727 130.465 1.00 261.48 ? 108 PHE B CD2 1 
ATOM   1989  C CE1 . PHE B 2 86  ? 134.208 218.633 128.824 1.00 261.48 ? 108 PHE B CE1 1 
ATOM   1990  C CE2 . PHE B 2 86  ? 134.022 217.098 130.647 1.00 261.48 ? 108 PHE B CE2 1 
ATOM   1991  C CZ  . PHE B 2 86  ? 133.455 218.052 129.825 1.00 261.48 ? 108 PHE B CZ  1 
ATOM   1992  N N   . GLY B 2 87  ? 139.141 216.018 126.609 1.00 265.91 ? 109 GLY B N   1 
ATOM   1993  C CA  . GLY B 2 87  ? 140.375 215.984 125.852 1.00 265.91 ? 109 GLY B CA  1 
ATOM   1994  C C   . GLY B 2 87  ? 140.681 214.657 125.201 1.00 265.91 ? 109 GLY B C   1 
ATOM   1995  O O   . GLY B 2 87  ? 141.845 214.394 124.880 1.00 265.91 ? 109 GLY B O   1 
ATOM   1996  N N   . GLN B 2 88  ? 139.669 213.810 124.998 1.00 265.79 ? 110 GLN B N   1 
ATOM   1997  C CA  . GLN B 2 88  ? 139.832 212.492 124.384 1.00 265.79 ? 110 GLN B CA  1 
ATOM   1998  C C   . GLN B 2 88  ? 140.831 211.627 125.148 1.00 265.79 ? 110 GLN B C   1 
ATOM   1999  O O   . GLN B 2 88  ? 141.564 210.832 124.554 1.00 265.79 ? 110 GLN B O   1 
ATOM   2000  C CB  . GLN B 2 88  ? 140.240 212.609 122.911 1.00 265.79 ? 110 GLN B CB  1 
ATOM   2001  C CG  . GLN B 2 88  ? 139.356 213.541 122.098 1.00 265.79 ? 110 GLN B CG  1 
ATOM   2002  C CD  . GLN B 2 88  ? 137.910 213.087 122.057 1.00 265.79 ? 110 GLN B CD  1 
ATOM   2003  O OE1 . GLN B 2 88  ? 137.623 211.890 122.046 1.00 265.79 ? 110 GLN B OE1 1 
ATOM   2004  N NE2 . GLN B 2 88  ? 136.990 214.044 122.036 1.00 265.79 ? 110 GLN B NE2 1 
ATOM   2005  N N   . ILE B 2 89  ? 140.868 211.774 126.468 1.00 263.16 ? 111 ILE B N   1 
ATOM   2006  C CA  . ILE B 2 89  ? 141.766 211.000 127.317 1.00 263.16 ? 111 ILE B CA  1 
ATOM   2007  C C   . ILE B 2 89  ? 141.006 209.790 127.846 1.00 263.16 ? 111 ILE B C   1 
ATOM   2008  O O   . ILE B 2 89  ? 139.979 209.936 128.518 1.00 263.16 ? 111 ILE B O   1 
ATOM   2009  C CB  . ILE B 2 89  ? 142.318 211.853 128.468 1.00 263.16 ? 111 ILE B CB  1 
ATOM   2010  C CG1 . ILE B 2 89  ? 143.065 213.069 127.918 1.00 263.16 ? 111 ILE B CG1 1 
ATOM   2011  C CG2 . ILE B 2 89  ? 143.228 211.020 129.358 1.00 263.16 ? 111 ILE B CG2 1 
ATOM   2012  C CD1 . ILE B 2 89  ? 143.633 213.973 128.989 1.00 263.16 ? 111 ILE B CD1 1 
ATOM   2013  N N   . GLU B 2 90  ? 141.510 208.596 127.544 1.00 255.96 ? 112 GLU B N   1 
ATOM   2014  C CA  . GLU B 2 90  ? 140.877 207.357 127.973 1.00 255.96 ? 112 GLU B CA  1 
ATOM   2015  C C   . GLU B 2 90  ? 141.434 206.932 129.325 1.00 255.96 ? 112 GLU B C   1 
ATOM   2016  O O   . GLU B 2 90  ? 142.652 206.938 129.532 1.00 255.96 ? 112 GLU B O   1 
ATOM   2017  C CB  . GLU B 2 90  ? 141.098 206.252 126.938 1.00 255.96 ? 112 GLU B CB  1 
ATOM   2018  C CG  . GLU B 2 90  ? 140.169 205.061 127.098 1.00 255.96 ? 112 GLU B CG  1 
ATOM   2019  C CD  . GLU B 2 90  ? 138.754 205.365 126.648 1.00 255.96 ? 112 GLU B CD  1 
ATOM   2020  O OE1 . GLU B 2 90  ? 138.585 206.215 125.748 1.00 255.96 ? 112 GLU B OE1 1 
ATOM   2021  O OE2 . GLU B 2 90  ? 137.810 204.757 127.195 1.00 255.96 ? 112 GLU B OE2 1 
ATOM   2022  N N   . GLN B 2 91  ? 140.541 206.564 130.240 1.00 245.32 ? 113 GLN B N   1 
ATOM   2023  C CA  . GLN B 2 91  ? 140.917 206.132 131.578 1.00 245.32 ? 113 GLN B CA  1 
ATOM   2024  C C   . GLN B 2 91  ? 140.246 204.802 131.888 1.00 245.32 ? 113 GLN B C   1 
ATOM   2025  O O   . GLN B 2 91  ? 139.075 204.595 131.557 1.00 245.32 ? 113 GLN B O   1 
ATOM   2026  C CB  . GLN B 2 91  ? 140.528 207.176 132.631 1.00 245.32 ? 113 GLN B CB  1 
ATOM   2027  C CG  . GLN B 2 91  ? 141.188 208.531 132.433 1.00 245.32 ? 113 GLN B CG  1 
ATOM   2028  C CD  . GLN B 2 91  ? 140.809 209.527 133.510 1.00 245.32 ? 113 GLN B CD  1 
ATOM   2029  O OE1 . GLN B 2 91  ? 140.086 209.197 134.449 1.00 245.32 ? 113 GLN B OE1 1 
ATOM   2030  N NE2 . GLN B 2 91  ? 141.296 210.756 133.378 1.00 245.32 ? 113 GLN B NE2 1 
ATOM   2031  N N   . ASN B 2 92  ? 140.994 203.907 132.527 1.00 227.04 ? 114 ASN B N   1 
ATOM   2032  C CA  . ASN B 2 92  ? 140.496 202.580 132.861 1.00 227.04 ? 114 ASN B CA  1 
ATOM   2033  C C   . ASN B 2 92  ? 139.805 202.598 134.218 1.00 227.04 ? 114 ASN B C   1 
ATOM   2034  O O   . ASN B 2 92  ? 140.272 203.243 135.161 1.00 227.04 ? 114 ASN B O   1 
ATOM   2035  C CB  . ASN B 2 92  ? 141.637 201.562 132.869 1.00 227.04 ? 114 ASN B CB  1 
ATOM   2036  C CG  . ASN B 2 92  ? 141.159 200.153 133.155 1.00 227.04 ? 114 ASN B CG  1 
ATOM   2037  O OD1 . ASN B 2 92  ? 141.110 199.723 134.307 1.00 227.04 ? 114 ASN B OD1 1 
ATOM   2038  N ND2 . ASN B 2 92  ? 140.801 199.425 132.103 1.00 227.04 ? 114 ASN B ND2 1 
ATOM   2039  N N   . VAL B 2 93  ? 138.686 201.881 134.309 1.00 217.86 ? 115 VAL B N   1 
ATOM   2040  C CA  . VAL B 2 93  ? 137.895 201.793 135.535 1.00 217.86 ? 115 VAL B CA  1 
ATOM   2041  C C   . VAL B 2 93  ? 138.005 200.408 136.165 1.00 217.86 ? 115 VAL B C   1 
ATOM   2042  O O   . VAL B 2 93  ? 138.404 200.273 137.323 1.00 217.86 ? 115 VAL B O   1 
ATOM   2043  C CB  . VAL B 2 93  ? 136.421 202.174 135.274 1.00 217.86 ? 115 VAL B CB  1 
ATOM   2044  C CG1 . VAL B 2 93  ? 135.587 201.951 136.525 1.00 217.86 ? 115 VAL B CG1 1 
ATOM   2045  C CG2 . VAL B 2 93  ? 136.320 203.618 134.807 1.00 217.86 ? 115 VAL B CG2 1 
ATOM   2046  N N   . TYR B 2 94  ? 137.654 199.364 135.416 1.00 200.22 ? 116 TYR B N   1 
ATOM   2047  C CA  . TYR B 2 94  ? 137.696 198.005 135.933 1.00 200.22 ? 116 TYR B CA  1 
ATOM   2048  C C   . TYR B 2 94  ? 137.865 197.035 134.773 1.00 200.22 ? 116 TYR B C   1 
ATOM   2049  O O   . TYR B 2 94  ? 137.495 197.328 133.633 1.00 200.22 ? 116 TYR B O   1 
ATOM   2050  C CB  . TYR B 2 94  ? 136.432 197.669 136.734 1.00 200.22 ? 116 TYR B CB  1 
ATOM   2051  C CG  . TYR B 2 94  ? 136.651 196.652 137.831 1.00 200.22 ? 116 TYR B CG  1 
ATOM   2052  C CD1 . TYR B 2 94  ? 136.391 195.305 137.618 1.00 200.22 ? 116 TYR B CD1 1 
ATOM   2053  C CD2 . TYR B 2 94  ? 137.117 197.040 139.080 1.00 200.22 ? 116 TYR B CD2 1 
ATOM   2054  C CE1 . TYR B 2 94  ? 136.589 194.373 138.617 1.00 200.22 ? 116 TYR B CE1 1 
ATOM   2055  C CE2 . TYR B 2 94  ? 137.318 196.114 140.086 1.00 200.22 ? 116 TYR B CE2 1 
ATOM   2056  C CZ  . TYR B 2 94  ? 137.052 194.782 139.849 1.00 200.22 ? 116 TYR B CZ  1 
ATOM   2057  O OH  . TYR B 2 94  ? 137.251 193.857 140.848 1.00 200.22 ? 116 TYR B OH  1 
ATOM   2058  N N   . GLY B 2 95  ? 138.433 195.871 135.079 1.00 190.60 ? 117 GLY B N   1 
ATOM   2059  C CA  . GLY B 2 95  ? 138.654 194.852 134.073 1.00 190.60 ? 117 GLY B CA  1 
ATOM   2060  C C   . GLY B 2 95  ? 138.514 193.439 134.601 1.00 190.60 ? 117 GLY B C   1 
ATOM   2061  O O   . GLY B 2 95  ? 139.043 193.112 135.667 1.00 190.60 ? 117 GLY B O   1 
ATOM   2062  N N   . VAL B 2 96  ? 137.801 192.590 133.860 1.00 174.24 ? 118 VAL B N   1 
ATOM   2063  C CA  . VAL B 2 96  ? 137.585 191.197 134.231 1.00 174.24 ? 118 VAL B CA  1 
ATOM   2064  C C   . VAL B 2 96  ? 137.821 190.324 133.004 1.00 174.24 ? 118 VAL B C   1 
ATOM   2065  O O   . VAL B 2 96  ? 137.882 190.804 131.871 1.00 174.24 ? 118 VAL B O   1 
ATOM   2066  C CB  . VAL B 2 96  ? 136.172 190.951 134.802 1.00 174.24 ? 118 VAL B CB  1 
ATOM   2067  C CG1 . VAL B 2 96  ? 135.969 191.733 136.091 1.00 174.24 ? 118 VAL B CG1 1 
ATOM   2068  C CG2 . VAL B 2 96  ? 135.114 191.322 133.774 1.00 174.24 ? 118 VAL B CG2 1 
ATOM   2069  N N   . THR B 2 97  ? 137.953 189.022 133.247 1.00 152.40 ? 119 THR B N   1 
ATOM   2070  C CA  . THR B 2 97  ? 138.190 188.039 132.198 1.00 152.40 ? 119 THR B CA  1 
ATOM   2071  C C   . THR B 2 97  ? 137.022 187.065 132.149 1.00 152.40 ? 119 THR B C   1 
ATOM   2072  O O   . THR B 2 97  ? 136.654 186.480 133.173 1.00 152.40 ? 119 THR B O   1 
ATOM   2073  C CB  . THR B 2 97  ? 139.499 187.281 132.435 1.00 152.40 ? 119 THR B CB  1 
ATOM   2074  O OG1 . THR B 2 97  ? 140.586 188.211 132.508 1.00 152.40 ? 119 THR B OG1 1 
ATOM   2075  C CG2 . THR B 2 97  ? 139.757 186.298 131.303 1.00 152.40 ? 119 THR B CG2 1 
ATOM   2076  N N   . MET B 2 98  ? 136.446 186.894 130.963 1.00 137.71 ? 120 MET B N   1 
ATOM   2077  C CA  . MET B 2 98  ? 135.326 185.985 130.755 1.00 137.71 ? 120 MET B CA  1 
ATOM   2078  C C   . MET B 2 98  ? 135.826 184.678 130.155 1.00 137.71 ? 120 MET B C   1 
ATOM   2079  O O   . MET B 2 98  ? 136.612 184.687 129.202 1.00 137.71 ? 120 MET B O   1 
ATOM   2080  C CB  . MET B 2 98  ? 134.272 186.615 129.843 1.00 137.71 ? 120 MET B CB  1 
ATOM   2081  C CG  . MET B 2 98  ? 133.128 185.678 129.486 1.00 137.71 ? 120 MET B CG  1 
ATOM   2082  S SD  . MET B 2 98  ? 131.761 186.505 128.652 1.00 137.71 ? 120 MET B SD  1 
ATOM   2083  C CE  . MET B 2 98  ? 132.558 187.059 127.148 1.00 137.71 ? 120 MET B CE  1 
ATOM   2084  N N   . LEU B 2 99  ? 135.368 183.562 130.713 1.00 112.52 ? 121 LEU B N   1 
ATOM   2085  C CA  . LEU B 2 99  ? 135.717 182.235 130.232 1.00 112.52 ? 121 LEU B CA  1 
ATOM   2086  C C   . LEU B 2 99  ? 134.541 181.630 129.477 1.00 112.52 ? 121 LEU B C   1 
ATOM   2087  O O   . LEU B 2 99  ? 133.381 181.976 129.720 1.00 112.52 ? 121 LEU B O   1 
ATOM   2088  C CB  . LEU B 2 99  ? 136.123 181.320 131.390 1.00 112.52 ? 121 LEU B CB  1 
ATOM   2089  C CG  . LEU B 2 99  ? 137.317 181.796 132.219 1.00 112.52 ? 121 LEU B CG  1 
ATOM   2090  C CD1 . LEU B 2 99  ? 137.564 180.867 133.396 1.00 112.52 ? 121 LEU B CD1 1 
ATOM   2091  C CD2 . LEU B 2 99  ? 138.558 181.906 131.349 1.00 112.52 ? 121 LEU B CD2 1 
ATOM   2092  N N   . SER B 2 100 ? 134.850 180.721 128.554 1.00 114.50 ? 122 SER B N   1 
ATOM   2093  C CA  . SER B 2 100 ? 133.843 180.072 127.719 1.00 114.50 ? 122 SER B CA  1 
ATOM   2094  C C   . SER B 2 100 ? 134.122 178.575 127.688 1.00 114.50 ? 122 SER B C   1 
ATOM   2095  O O   . SER B 2 100 ? 135.165 178.145 127.185 1.00 114.50 ? 122 SER B O   1 
ATOM   2096  C CB  . SER B 2 100 ? 133.839 180.655 126.307 1.00 114.50 ? 122 SER B CB  1 
ATOM   2097  O OG  . SER B 2 100 ? 133.283 181.959 126.297 1.00 114.50 ? 122 SER B OG  1 
ATOM   2098  N N   . GLY B 2 101 ? 133.192 177.789 128.222 1.00 111.64 ? 123 GLY B N   1 
ATOM   2099  C CA  . GLY B 2 101 ? 133.329 176.345 128.224 1.00 111.64 ? 123 GLY B CA  1 
ATOM   2100  C C   . GLY B 2 101 ? 131.993 175.681 128.459 1.00 111.64 ? 123 GLY B C   1 
ATOM   2101  O O   . GLY B 2 101 ? 131.058 176.293 128.983 1.00 111.64 ? 123 GLY B O   1 
ATOM   2102  N N   . PHE B 2 102 ? 131.911 174.404 128.057 1.00 101.15 ? 124 PHE B N   1 
ATOM   2103  C CA  . PHE B 2 102 ? 130.654 173.697 128.243 1.00 101.15 ? 124 PHE B CA  1 
ATOM   2104  C C   . PHE B 2 102 ? 130.730 172.772 129.454 1.00 101.15 ? 124 PHE B C   1 
ATOM   2105  O O   . PHE B 2 102 ? 131.817 172.324 129.834 1.00 101.15 ? 124 PHE B O   1 
ATOM   2106  C CB  . PHE B 2 102 ? 130.295 172.885 126.993 1.00 101.15 ? 124 PHE B CB  1 
ATOM   2107  C CG  . PHE B 2 102 ? 131.481 172.309 126.277 1.00 101.15 ? 124 PHE B CG  1 
ATOM   2108  C CD1 . PHE B 2 102 ? 132.047 172.972 125.201 1.00 101.15 ? 124 PHE B CD1 1 
ATOM   2109  C CD2 . PHE B 2 102 ? 132.021 171.097 126.669 1.00 101.15 ? 124 PHE B CD2 1 
ATOM   2110  C CE1 . PHE B 2 102 ? 133.135 172.442 124.536 1.00 101.15 ? 124 PHE B CE1 1 
ATOM   2111  C CE2 . PHE B 2 102 ? 133.107 170.561 126.008 1.00 101.15 ? 124 PHE B CE2 1 
ATOM   2112  C CZ  . PHE B 2 102 ? 133.665 171.234 124.941 1.00 101.15 ? 124 PHE B CZ  1 
ATOM   2113  N N   . PRO B 2 103 ? 129.596 172.476 130.087 1.00 93.21  ? 125 PRO B N   1 
ATOM   2114  C CA  . PRO B 2 103 ? 129.607 171.633 131.290 1.00 93.21  ? 125 PRO B CA  1 
ATOM   2115  C C   . PRO B 2 103 ? 130.069 170.223 130.970 1.00 93.21  ? 125 PRO B C   1 
ATOM   2116  O O   . PRO B 2 103 ? 129.998 169.784 129.813 1.00 93.21  ? 125 PRO B O   1 
ATOM   2117  C CB  . PRO B 2 103 ? 128.139 171.649 131.745 1.00 93.21  ? 125 PRO B CB  1 
ATOM   2118  C CG  . PRO B 2 103 ? 127.366 171.997 130.519 1.00 93.21  ? 125 PRO B CG  1 
ATOM   2119  C CD  . PRO B 2 103 ? 128.239 172.948 129.764 1.00 93.21  ? 125 PRO B CD  1 
ATOM   2120  N N   . PRO B 2 104 ? 130.550 169.478 131.973 1.00 82.00  ? 126 PRO B N   1 
ATOM   2121  C CA  . PRO B 2 104 ? 131.042 168.119 131.711 1.00 82.00  ? 126 PRO B CA  1 
ATOM   2122  C C   . PRO B 2 104 ? 129.924 167.124 131.444 1.00 82.00  ? 126 PRO B C   1 
ATOM   2123  O O   . PRO B 2 104 ? 128.742 167.482 131.455 1.00 82.00  ? 126 PRO B O   1 
ATOM   2124  C CB  . PRO B 2 104 ? 131.802 167.772 132.997 1.00 82.00  ? 126 PRO B CB  1 
ATOM   2125  C CG  . PRO B 2 104 ? 131.121 168.574 134.049 1.00 82.00  ? 126 PRO B CG  1 
ATOM   2126  C CD  . PRO B 2 104 ? 130.712 169.861 133.386 1.00 82.00  ? 126 PRO B CD  1 
ATOM   2127  N N   . ASP B 2 105 ? 130.293 165.871 131.208 1.00 85.35  ? 127 ASP B N   1 
ATOM   2128  C CA  . ASP B 2 105 ? 129.355 164.796 130.923 1.00 85.35  ? 127 ASP B CA  1 
ATOM   2129  C C   . ASP B 2 105 ? 129.361 163.786 132.067 1.00 85.35  ? 127 ASP B C   1 
ATOM   2130  O O   . ASP B 2 105 ? 130.114 163.908 133.037 1.00 85.35  ? 127 ASP B O   1 
ATOM   2131  C CB  . ASP B 2 105 ? 129.698 164.126 129.591 1.00 85.35  ? 127 ASP B CB  1 
ATOM   2132  C CG  . ASP B 2 105 ? 131.112 163.577 129.561 1.00 85.35  ? 127 ASP B CG  1 
ATOM   2133  O OD1 . ASP B 2 105 ? 131.334 162.469 130.091 1.00 85.35  ? 127 ASP B OD1 1 
ATOM   2134  O OD2 . ASP B 2 105 ? 132.002 164.256 129.007 1.00 85.35  ? 127 ASP B OD2 1 
ATOM   2135  N N   . LYS B 2 106 ? 128.507 162.778 131.942 1.00 69.25  ? 128 LYS B N   1 
ATOM   2136  C CA  . LYS B 2 106 ? 128.404 161.744 132.964 1.00 69.25  ? 128 LYS B CA  1 
ATOM   2137  C C   . LYS B 2 106 ? 129.564 160.767 132.826 1.00 69.25  ? 128 LYS B C   1 
ATOM   2138  O O   . LYS B 2 106 ? 129.696 160.124 131.778 1.00 69.25  ? 128 LYS B O   1 
ATOM   2139  C CB  . LYS B 2 106 ? 127.078 161.007 132.843 1.00 69.25  ? 128 LYS B CB  1 
ATOM   2140  C CG  . LYS B 2 106 ? 126.526 160.497 134.163 1.00 69.25  ? 128 LYS B CG  1 
ATOM   2141  C CD  . LYS B 2 106 ? 125.044 160.181 134.053 1.00 69.25  ? 128 LYS B CD  1 
ATOM   2142  C CE  . LYS B 2 106 ? 124.424 159.952 135.421 1.00 69.25  ? 128 LYS B CE  1 
ATOM   2143  N NZ  . LYS B 2 106 ? 122.945 159.802 135.343 1.00 69.25  ? 128 LYS B NZ  1 
ATOM   2144  N N   . PRO B 2 107 ? 130.420 160.627 133.836 1.00 61.09  ? 129 PRO B N   1 
ATOM   2145  C CA  . PRO B 2 107 ? 131.541 159.688 133.726 1.00 61.09  ? 129 PRO B CA  1 
ATOM   2146  C C   . PRO B 2 107 ? 131.061 158.249 133.635 1.00 61.09  ? 129 PRO B C   1 
ATOM   2147  O O   . PRO B 2 107 ? 129.975 157.897 134.101 1.00 61.09  ? 129 PRO B O   1 
ATOM   2148  C CB  . PRO B 2 107 ? 132.336 159.927 135.017 1.00 61.09  ? 129 PRO B CB  1 
ATOM   2149  C CG  . PRO B 2 107 ? 131.884 161.266 135.512 1.00 61.09  ? 129 PRO B CG  1 
ATOM   2150  C CD  . PRO B 2 107 ? 130.454 161.385 135.097 1.00 61.09  ? 129 PRO B CD  1 
ATOM   2151  N N   . THR B 2 108 ? 131.891 157.412 133.017 1.00 67.35  ? 130 THR B N   1 
ATOM   2152  C CA  . THR B 2 108 ? 131.588 155.997 132.842 1.00 67.35  ? 130 THR B CA  1 
ATOM   2153  C C   . THR B 2 108 ? 132.853 155.198 133.138 1.00 67.35  ? 130 THR B C   1 
ATOM   2154  O O   . THR B 2 108 ? 133.856 155.741 133.614 1.00 67.35  ? 130 THR B O   1 
ATOM   2155  C CB  . THR B 2 108 ? 131.052 155.720 131.430 1.00 67.35  ? 130 THR B CB  1 
ATOM   2156  O OG1 . THR B 2 108 ? 131.855 156.413 130.466 1.00 67.35  ? 130 THR B OG1 1 
ATOM   2157  C CG2 . THR B 2 108 ? 129.605 156.176 131.304 1.00 67.35  ? 130 THR B CG2 1 
ATOM   2158  N N   . ASN B 2 109 ? 132.797 153.895 132.853 1.00 82.66  ? 131 ASN B N   1 
ATOM   2159  C CA  . ASN B 2 109 ? 133.932 152.987 133.031 1.00 82.66  ? 131 ASN B CA  1 
ATOM   2160  C C   . ASN B 2 109 ? 134.470 153.045 134.460 1.00 82.66  ? 131 ASN B C   1 
ATOM   2161  O O   . ASN B 2 109 ? 135.673 153.182 134.693 1.00 82.66  ? 131 ASN B O   1 
ATOM   2162  C CB  . ASN B 2 109 ? 135.039 153.286 132.018 1.00 82.66  ? 131 ASN B CB  1 
ATOM   2163  C CG  . ASN B 2 109 ? 134.551 153.224 130.583 1.00 82.66  ? 131 ASN B CG  1 
ATOM   2164  O OD1 . ASN B 2 109 ? 133.590 153.901 130.218 1.00 82.66  ? 131 ASN B OD1 1 
ATOM   2165  N ND2 . ASN B 2 109 ? 135.213 152.415 129.757 1.00 82.66  ? 131 ASN B ND2 1 
ATOM   2166  N N   . LEU B 2 110 ? 133.562 152.940 135.426 1.00 65.46  ? 132 LEU B N   1 
ATOM   2167  C CA  . LEU B 2 110 ? 133.931 152.996 136.838 1.00 65.46  ? 132 LEU B CA  1 
ATOM   2168  C C   . LEU B 2 110 ? 134.364 151.605 137.283 1.00 65.46  ? 132 LEU B C   1 
ATOM   2169  O O   . LEU B 2 110 ? 133.532 150.727 137.519 1.00 65.46  ? 132 LEU B O   1 
ATOM   2170  C CB  . LEU B 2 110 ? 132.769 153.511 137.679 1.00 65.46  ? 132 LEU B CB  1 
ATOM   2171  C CG  . LEU B 2 110 ? 133.062 153.689 139.169 1.00 65.46  ? 132 LEU B CG  1 
ATOM   2172  C CD1 . LEU B 2 110 ? 134.231 154.637 139.375 1.00 65.46  ? 132 LEU B CD1 1 
ATOM   2173  C CD2 . LEU B 2 110 ? 131.828 154.190 139.898 1.00 65.46  ? 132 LEU B CD2 1 
ATOM   2174  N N   . THR B 2 111 ? 135.674 151.401 137.396 1.00 65.20  ? 133 THR B N   1 
ATOM   2175  C CA  . THR B 2 111 ? 136.237 150.135 137.836 1.00 65.20  ? 133 THR B CA  1 
ATOM   2176  C C   . THR B 2 111 ? 137.251 150.390 138.941 1.00 65.20  ? 133 THR B C   1 
ATOM   2177  O O   . THR B 2 111 ? 137.865 151.458 139.009 1.00 65.20  ? 133 THR B O   1 
ATOM   2178  C CB  . THR B 2 111 ? 136.909 149.378 136.683 1.00 65.20  ? 133 THR B CB  1 
ATOM   2179  O OG1 . THR B 2 111 ? 137.864 150.232 136.040 1.00 65.20  ? 133 THR B OG1 1 
ATOM   2180  C CG2 . THR B 2 111 ? 135.874 148.923 135.665 1.00 65.20  ? 133 THR B CG2 1 
ATOM   2181  N N   . CYS B 2 112 ? 137.422 149.394 139.809 1.00 56.66  ? 134 CYS B N   1 
ATOM   2182  C CA  . CYS B 2 112 ? 138.343 149.495 140.930 1.00 56.66  ? 134 CYS B CA  1 
ATOM   2183  C C   . CYS B 2 112 ? 139.157 148.215 141.035 1.00 56.66  ? 134 CYS B C   1 
ATOM   2184  O O   . CYS B 2 112 ? 138.645 147.122 140.781 1.00 56.66  ? 134 CYS B O   1 
ATOM   2185  C CB  . CYS B 2 112 ? 137.597 149.751 142.246 1.00 56.66  ? 134 CYS B CB  1 
ATOM   2186  S SG  . CYS B 2 112 ? 136.640 151.283 142.273 1.00 56.66  ? 134 CYS B SG  1 
ATOM   2187  N N   . ILE B 2 113 ? 140.425 148.361 141.411 1.00 56.02  ? 135 ILE B N   1 
ATOM   2188  C CA  . ILE B 2 113 ? 141.335 147.237 141.584 1.00 56.02  ? 135 ILE B CA  1 
ATOM   2189  C C   . ILE B 2 113 ? 142.015 147.370 142.940 1.00 56.02  ? 135 ILE B C   1 
ATOM   2190  O O   . ILE B 2 113 ? 142.366 148.477 143.364 1.00 56.02  ? 135 ILE B O   1 
ATOM   2191  C CB  . ILE B 2 113 ? 142.374 147.161 140.442 1.00 56.02  ? 135 ILE B CB  1 
ATOM   2192  C CG1 . ILE B 2 113 ? 143.235 145.903 140.576 1.00 56.02  ? 135 ILE B CG1 1 
ATOM   2193  C CG2 . ILE B 2 113 ? 143.232 148.418 140.394 1.00 56.02  ? 135 ILE B CG2 1 
ATOM   2194  C CD1 . ILE B 2 113 ? 144.056 145.592 139.344 1.00 56.02  ? 135 ILE B CD1 1 
ATOM   2195  N N   . VAL B 2 114 ? 142.177 146.245 143.629 1.00 54.58  ? 136 VAL B N   1 
ATOM   2196  C CA  . VAL B 2 114 ? 142.793 146.204 144.950 1.00 54.58  ? 136 VAL B CA  1 
ATOM   2197  C C   . VAL B 2 114 ? 144.069 145.383 144.841 1.00 54.58  ? 136 VAL B C   1 
ATOM   2198  O O   . VAL B 2 114 ? 144.019 144.154 144.715 1.00 54.58  ? 136 VAL B O   1 
ATOM   2199  C CB  . VAL B 2 114 ? 141.846 145.617 146.004 1.00 54.58  ? 136 VAL B CB  1 
ATOM   2200  C CG1 . VAL B 2 114 ? 142.520 145.597 147.367 1.00 54.58  ? 136 VAL B CG1 1 
ATOM   2201  C CG2 . VAL B 2 114 ? 140.551 146.410 146.055 1.00 54.58  ? 136 VAL B CG2 1 
ATOM   2202  N N   . ASN B 2 115 ? 145.214 146.057 144.888 1.00 62.89  ? 137 ASN B N   1 
ATOM   2203  C CA  . ASN B 2 115 ? 146.493 145.366 144.866 1.00 62.89  ? 137 ASN B CA  1 
ATOM   2204  C C   . ASN B 2 115 ? 146.789 144.761 146.233 1.00 62.89  ? 137 ASN B C   1 
ATOM   2205  O O   . ASN B 2 115 ? 146.383 145.289 147.272 1.00 62.89  ? 137 ASN B O   1 
ATOM   2206  C CB  . ASN B 2 115 ? 147.615 146.322 144.462 1.00 62.89  ? 137 ASN B CB  1 
ATOM   2207  C CG  . ASN B 2 115 ? 147.382 146.951 143.104 1.00 62.89  ? 137 ASN B CG  1 
ATOM   2208  O OD1 . ASN B 2 115 ? 147.793 146.410 142.078 1.00 62.89  ? 137 ASN B OD1 1 
ATOM   2209  N ND2 . ASN B 2 115 ? 146.719 148.102 143.091 1.00 62.89  ? 137 ASN B ND2 1 
ATOM   2210  N N   . GLU B 2 116 ? 147.503 143.639 146.223 1.00 65.57  ? 138 GLU B N   1 
ATOM   2211  C CA  . GLU B 2 116 ? 147.839 142.952 147.464 1.00 65.57  ? 138 GLU B CA  1 
ATOM   2212  C C   . GLU B 2 116 ? 148.837 143.782 148.261 1.00 65.57  ? 138 GLU B C   1 
ATOM   2213  O O   . GLU B 2 116 ? 149.941 144.067 147.785 1.00 65.57  ? 138 GLU B O   1 
ATOM   2214  C CB  . GLU B 2 116 ? 148.406 141.567 147.166 1.00 65.57  ? 138 GLU B CB  1 
ATOM   2215  C CG  . GLU B 2 116 ? 148.890 140.821 148.398 1.00 65.57  ? 138 GLU B CG  1 
ATOM   2216  C CD  . GLU B 2 116 ? 149.223 139.371 148.108 1.00 65.57  ? 138 GLU B CD  1 
ATOM   2217  O OE1 . GLU B 2 116 ? 149.097 138.536 149.027 1.00 65.57  ? 138 GLU B OE1 1 
ATOM   2218  O OE2 . GLU B 2 116 ? 149.609 139.066 146.960 1.00 65.57  ? 138 GLU B OE2 1 
ATOM   2219  N N   . GLY B 2 117 ? 148.450 144.169 149.473 1.00 68.14  ? 139 GLY B N   1 
ATOM   2220  C CA  . GLY B 2 117 ? 149.294 144.980 150.323 1.00 68.14  ? 139 GLY B CA  1 
ATOM   2221  C C   . GLY B 2 117 ? 149.173 146.472 150.122 1.00 68.14  ? 139 GLY B C   1 
ATOM   2222  O O   . GLY B 2 117 ? 149.994 147.221 150.665 1.00 68.14  ? 139 GLY B O   1 
ATOM   2223  N N   . LYS B 2 118 ? 148.181 146.932 149.361 1.00 67.47  ? 140 LYS B N   1 
ATOM   2224  C CA  . LYS B 2 118 ? 147.981 148.351 149.112 1.00 67.47  ? 140 LYS B CA  1 
ATOM   2225  C C   . LYS B 2 118 ? 146.499 148.672 149.232 1.00 67.47  ? 140 LYS B C   1 
ATOM   2226  O O   . LYS B 2 118 ? 145.656 147.783 149.382 1.00 67.47  ? 140 LYS B O   1 
ATOM   2227  C CB  . LYS B 2 118 ? 148.511 148.762 147.732 1.00 67.47  ? 140 LYS B CB  1 
ATOM   2228  C CG  . LYS B 2 118 ? 150.010 148.581 147.559 1.00 67.47  ? 140 LYS B CG  1 
ATOM   2229  C CD  . LYS B 2 118 ? 150.450 148.942 146.150 1.00 67.47  ? 140 LYS B CD  1 
ATOM   2230  C CE  . LYS B 2 118 ? 151.938 148.703 145.960 1.00 67.47  ? 140 LYS B CE  1 
ATOM   2231  N NZ  . LYS B 2 118 ? 152.384 149.055 144.584 1.00 67.47  ? 140 LYS B NZ  1 
ATOM   2232  N N   . ASN B 2 119 ? 146.184 149.963 149.164 1.00 67.14  ? 141 ASN B N   1 
ATOM   2233  C CA  . ASN B 2 119 ? 144.805 150.410 149.252 1.00 67.14  ? 141 ASN B CA  1 
ATOM   2234  C C   . ASN B 2 119 ? 144.096 150.234 147.911 1.00 67.14  ? 141 ASN B C   1 
ATOM   2235  O O   . ASN B 2 119 ? 144.706 149.916 146.887 1.00 67.14  ? 141 ASN B O   1 
ATOM   2236  C CB  . ASN B 2 119 ? 144.742 151.869 149.703 1.00 67.14  ? 141 ASN B CB  1 
ATOM   2237  C CG  . ASN B 2 119 ? 145.255 152.063 151.116 1.00 67.14  ? 141 ASN B CG  1 
ATOM   2238  O OD1 . ASN B 2 119 ? 145.117 151.183 151.965 1.00 67.14  ? 141 ASN B OD1 1 
ATOM   2239  N ND2 . ASN B 2 119 ? 145.851 153.221 151.375 1.00 67.14  ? 141 ASN B ND2 1 
ATOM   2240  N N   . MET B 2 120 ? 142.783 150.449 147.928 1.00 63.45  ? 142 MET B N   1 
ATOM   2241  C CA  . MET B 2 120 ? 141.966 150.277 146.735 1.00 63.45  ? 142 MET B CA  1 
ATOM   2242  C C   . MET B 2 120 ? 142.181 151.439 145.774 1.00 63.45  ? 142 MET B C   1 
ATOM   2243  O O   . MET B 2 120 ? 142.169 152.604 146.182 1.00 63.45  ? 142 MET B O   1 
ATOM   2244  C CB  . MET B 2 120 ? 140.491 150.168 147.117 1.00 63.45  ? 142 MET B CB  1 
ATOM   2245  C CG  . MET B 2 120 ? 139.552 150.010 145.935 1.00 63.45  ? 142 MET B CG  1 
ATOM   2246  S SD  . MET B 2 120 ? 137.850 149.724 146.449 1.00 63.45  ? 142 MET B SD  1 
ATOM   2247  C CE  . MET B 2 120 ? 137.548 151.183 147.440 1.00 63.45  ? 142 MET B CE  1 
ATOM   2248  N N   . LEU B 2 121 ? 142.378 151.119 144.498 1.00 61.82  ? 143 LEU B N   1 
ATOM   2249  C CA  . LEU B 2 121 ? 142.590 152.111 143.454 1.00 61.82  ? 143 LEU B CA  1 
ATOM   2250  C C   . LEU B 2 121 ? 141.464 152.018 142.435 1.00 61.82  ? 143 LEU B C   1 
ATOM   2251  O O   . LEU B 2 121 ? 141.182 150.933 141.915 1.00 61.82  ? 143 LEU B O   1 
ATOM   2252  C CB  . LEU B 2 121 ? 143.943 151.909 142.769 1.00 61.82  ? 143 LEU B CB  1 
ATOM   2253  C CG  . LEU B 2 121 ? 144.225 152.801 141.558 1.00 61.82  ? 143 LEU B CG  1 
ATOM   2254  C CD1 . LEU B 2 121 ? 144.212 154.267 141.959 1.00 61.82  ? 143 LEU B CD1 1 
ATOM   2255  C CD2 . LEU B 2 121 ? 145.551 152.428 140.915 1.00 61.82  ? 143 LEU B CD2 1 
ATOM   2256  N N   . CYS B 2 122 ? 140.827 153.151 142.152 1.00 68.71  ? 144 CYS B N   1 
ATOM   2257  C CA  . CYS B 2 122 ? 139.730 153.220 141.200 1.00 68.71  ? 144 CYS B CA  1 
ATOM   2258  C C   . CYS B 2 122 ? 140.090 154.161 140.058 1.00 68.71  ? 144 CYS B C   1 
ATOM   2259  O O   . CYS B 2 122 ? 140.802 155.151 140.248 1.00 68.71  ? 144 CYS B O   1 
ATOM   2260  C CB  . CYS B 2 122 ? 138.436 153.691 141.874 1.00 68.71  ? 144 CYS B CB  1 
ATOM   2261  S SG  . CYS B 2 122 ? 137.857 152.615 143.204 1.00 68.71  ? 144 CYS B SG  1 
ATOM   2262  N N   . GLN B 2 123 ? 139.590 153.840 138.866 1.00 73.79  ? 145 GLN B N   1 
ATOM   2263  C CA  . GLN B 2 123 ? 139.862 154.629 137.674 1.00 73.79  ? 145 GLN B CA  1 
ATOM   2264  C C   . GLN B 2 123 ? 138.583 154.781 136.864 1.00 73.79  ? 145 GLN B C   1 
ATOM   2265  O O   . GLN B 2 123 ? 137.661 153.966 136.958 1.00 73.79  ? 145 GLN B O   1 
ATOM   2266  C CB  . GLN B 2 123 ? 140.961 153.992 136.811 1.00 73.79  ? 145 GLN B CB  1 
ATOM   2267  C CG  . GLN B 2 123 ? 142.340 154.006 137.450 1.00 73.79  ? 145 GLN B CG  1 
ATOM   2268  C CD  . GLN B 2 123 ? 143.395 153.364 136.572 1.00 73.79  ? 145 GLN B CD  1 
ATOM   2269  O OE1 . GLN B 2 123 ? 143.077 152.631 135.635 1.00 73.79  ? 145 GLN B OE1 1 
ATOM   2270  N NE2 . GLN B 2 123 ? 144.660 153.637 136.871 1.00 73.79  ? 145 GLN B NE2 1 
ATOM   2271  N N   . TRP B 2 124 ? 138.540 155.840 136.060 1.00 66.51  ? 146 TRP B N   1 
ATOM   2272  C CA  . TRP B 2 124 ? 137.392 156.119 135.207 1.00 66.51  ? 146 TRP B CA  1 
ATOM   2273  C C   . TRP B 2 124 ? 137.841 157.035 134.078 1.00 66.51  ? 146 TRP B C   1 
ATOM   2274  O O   . TRP B 2 124 ? 138.938 157.597 134.106 1.00 66.51  ? 146 TRP B O   1 
ATOM   2275  C CB  . TRP B 2 124 ? 136.244 156.750 136.002 1.00 66.51  ? 146 TRP B CB  1 
ATOM   2276  C CG  . TRP B 2 124 ? 136.585 158.081 136.599 1.00 66.51  ? 146 TRP B CG  1 
ATOM   2277  C CD1 . TRP B 2 124 ? 136.463 159.302 136.002 1.00 66.51  ? 146 TRP B CD1 1 
ATOM   2278  C CD2 . TRP B 2 124 ? 137.103 158.327 137.911 1.00 66.51  ? 146 TRP B CD2 1 
ATOM   2279  N NE1 . TRP B 2 124 ? 136.873 160.292 136.860 1.00 66.51  ? 146 TRP B NE1 1 
ATOM   2280  C CE2 . TRP B 2 124 ? 137.271 159.720 138.040 1.00 66.51  ? 146 TRP B CE2 1 
ATOM   2281  C CE3 . TRP B 2 124 ? 137.442 157.505 138.990 1.00 66.51  ? 146 TRP B CE3 1 
ATOM   2282  C CZ2 . TRP B 2 124 ? 137.763 160.308 139.202 1.00 66.51  ? 146 TRP B CZ2 1 
ATOM   2283  C CZ3 . TRP B 2 124 ? 137.929 158.092 140.144 1.00 66.51  ? 146 TRP B CZ3 1 
ATOM   2284  C CH2 . TRP B 2 124 ? 138.084 159.479 140.241 1.00 66.51  ? 146 TRP B CH2 1 
ATOM   2285  N N   . ASP B 2 125 ? 136.974 157.176 133.076 1.00 70.89  ? 147 ASP B N   1 
ATOM   2286  C CA  . ASP B 2 125 ? 137.363 158.085 132.008 1.00 70.89  ? 147 ASP B CA  1 
ATOM   2287  C C   . ASP B 2 125 ? 136.617 159.408 132.130 1.00 70.89  ? 147 ASP B C   1 
ATOM   2288  O O   . ASP B 2 125 ? 135.431 159.424 132.481 1.00 70.89  ? 147 ASP B O   1 
ATOM   2289  C CB  . ASP B 2 125 ? 137.087 157.469 130.635 1.00 70.89  ? 147 ASP B CB  1 
ATOM   2290  C CG  . ASP B 2 125 ? 135.608 157.272 130.367 1.00 70.89  ? 147 ASP B CG  1 
ATOM   2291  O OD1 . ASP B 2 125 ? 134.872 156.926 131.313 1.00 70.89  ? 147 ASP B OD1 1 
ATOM   2292  O OD2 . ASP B 2 125 ? 135.182 157.465 129.210 1.00 70.89  ? 147 ASP B OD2 1 
ATOM   2293  N N   . PRO B 2 126 ? 137.282 160.531 131.859 1.00 71.93  ? 148 PRO B N   1 
ATOM   2294  C CA  . PRO B 2 126 ? 136.614 161.832 132.000 1.00 71.93  ? 148 PRO B CA  1 
ATOM   2295  C C   . PRO B 2 126 ? 135.652 162.127 130.861 1.00 71.93  ? 148 PRO B C   1 
ATOM   2296  O O   . PRO B 2 126 ? 134.587 162.713 131.077 1.00 71.93  ? 148 PRO B O   1 
ATOM   2297  C CB  . PRO B 2 126 ? 137.785 162.822 132.019 1.00 71.93  ? 148 PRO B CB  1 
ATOM   2298  C CG  . PRO B 2 126 ? 138.855 162.145 131.234 1.00 71.93  ? 148 PRO B CG  1 
ATOM   2299  C CD  . PRO B 2 126 ? 138.698 160.667 131.477 1.00 71.93  ? 148 PRO B CD  1 
ATOM   2300  N N   . GLY B 2 127 ? 136.013 161.722 129.646 1.00 81.28  ? 149 GLY B N   1 
ATOM   2301  C CA  . GLY B 2 127 ? 135.187 161.993 128.486 1.00 81.28  ? 149 GLY B CA  1 
ATOM   2302  C C   . GLY B 2 127 ? 135.741 163.090 127.600 1.00 81.28  ? 149 GLY B C   1 
ATOM   2303  O O   . GLY B 2 127 ? 136.767 162.904 126.940 1.00 81.28  ? 149 GLY B O   1 
ATOM   2304  N N   . ARG B 2 128 ? 135.071 164.237 127.578 1.00 95.51  ? 150 ARG B N   1 
ATOM   2305  C CA  . ARG B 2 128 ? 135.472 165.369 126.758 1.00 95.51  ? 150 ARG B CA  1 
ATOM   2306  C C   . ARG B 2 128 ? 136.182 166.423 127.601 1.00 95.51  ? 150 ARG B C   1 
ATOM   2307  O O   . ARG B 2 128 ? 136.077 166.449 128.829 1.00 95.51  ? 150 ARG B O   1 
ATOM   2308  C CB  . ARG B 2 128 ? 134.259 165.990 126.060 1.00 95.51  ? 150 ARG B CB  1 
ATOM   2309  C CG  . ARG B 2 128 ? 133.251 166.616 127.012 1.00 95.51  ? 150 ARG B CG  1 
ATOM   2310  C CD  . ARG B 2 128 ? 132.048 167.165 126.262 1.00 95.51  ? 150 ARG B CD  1 
ATOM   2311  N NE  . ARG B 2 128 ? 131.336 166.121 125.531 1.00 95.51  ? 150 ARG B NE  1 
ATOM   2312  C CZ  . ARG B 2 128 ? 130.255 166.336 124.787 1.00 95.51  ? 150 ARG B CZ  1 
ATOM   2313  N NH1 . ARG B 2 128 ? 129.672 165.326 124.156 1.00 95.51  ? 150 ARG B NH1 1 
ATOM   2314  N NH2 . ARG B 2 128 ? 129.758 167.560 124.673 1.00 95.51  ? 150 ARG B NH2 1 
ATOM   2315  N N   . GLU B 2 129 ? 136.912 167.300 126.916 1.00 100.12 ? 151 GLU B N   1 
ATOM   2316  C CA  . GLU B 2 129 ? 137.620 168.386 127.579 1.00 100.12 ? 151 GLU B CA  1 
ATOM   2317  C C   . GLU B 2 129 ? 136.665 169.541 127.852 1.00 100.12 ? 151 GLU B C   1 
ATOM   2318  O O   . GLU B 2 129 ? 135.993 170.032 126.940 1.00 100.12 ? 151 GLU B O   1 
ATOM   2319  C CB  . GLU B 2 129 ? 138.793 168.859 126.721 1.00 100.12 ? 151 GLU B CB  1 
ATOM   2320  C CG  . GLU B 2 129 ? 139.550 170.049 127.291 1.00 100.12 ? 151 GLU B CG  1 
ATOM   2321  C CD  . GLU B 2 129 ? 140.439 169.675 128.463 1.00 100.12 ? 151 GLU B CD  1 
ATOM   2322  O OE1 . GLU B 2 129 ? 139.910 169.472 129.576 1.00 100.12 ? 151 GLU B OE1 1 
ATOM   2323  O OE2 . GLU B 2 129 ? 141.669 169.583 128.270 1.00 100.12 ? 151 GLU B OE2 1 
ATOM   2324  N N   . THR B 2 130 ? 136.610 169.977 129.110 1.00 94.93  ? 152 THR B N   1 
ATOM   2325  C CA  . THR B 2 130 ? 135.700 171.036 129.525 1.00 94.93  ? 152 THR B CA  1 
ATOM   2326  C C   . THR B 2 130 ? 136.310 172.428 129.428 1.00 94.93  ? 152 THR B C   1 
ATOM   2327  O O   . THR B 2 130 ? 135.569 173.414 129.509 1.00 94.93  ? 152 THR B O   1 
ATOM   2328  C CB  . THR B 2 130 ? 135.230 170.797 130.964 1.00 94.93  ? 152 THR B CB  1 
ATOM   2329  O OG1 . THR B 2 130 ? 136.358 170.822 131.847 1.00 94.93  ? 152 THR B OG1 1 
ATOM   2330  C CG2 . THR B 2 130 ? 134.536 169.450 131.079 1.00 94.93  ? 152 THR B CG2 1 
ATOM   2331  N N   . TYR B 2 131 ? 137.630 172.530 129.269 1.00 101.41 ? 153 TYR B N   1 
ATOM   2332  C CA  . TYR B 2 131 ? 138.349 173.801 129.183 1.00 101.41 ? 153 TYR B CA  1 
ATOM   2333  C C   . TYR B 2 131 ? 138.178 174.653 130.437 1.00 101.41 ? 153 TYR B C   1 
ATOM   2334  O O   . TYR B 2 131 ? 138.366 175.873 130.392 1.00 101.41 ? 153 TYR B O   1 
ATOM   2335  C CB  . TYR B 2 131 ? 137.928 174.602 127.944 1.00 101.41 ? 153 TYR B CB  1 
ATOM   2336  C CG  . TYR B 2 131 ? 137.967 173.809 126.657 1.00 101.41 ? 153 TYR B CG  1 
ATOM   2337  C CD1 . TYR B 2 131 ? 139.170 173.550 126.015 1.00 101.41 ? 153 TYR B CD1 1 
ATOM   2338  C CD2 . TYR B 2 131 ? 136.799 173.324 126.083 1.00 101.41 ? 153 TYR B CD2 1 
ATOM   2339  C CE1 . TYR B 2 131 ? 139.210 172.827 124.837 1.00 101.41 ? 153 TYR B CE1 1 
ATOM   2340  C CE2 . TYR B 2 131 ? 136.829 172.600 124.906 1.00 101.41 ? 153 TYR B CE2 1 
ATOM   2341  C CZ  . TYR B 2 131 ? 138.037 172.355 124.288 1.00 101.41 ? 153 TYR B CZ  1 
ATOM   2342  O OH  . TYR B 2 131 ? 138.071 171.635 123.117 1.00 101.41 ? 153 TYR B OH  1 
ATOM   2343  N N   . LEU B 2 132 ? 137.826 174.033 131.561 1.00 91.48  ? 154 LEU B N   1 
ATOM   2344  C CA  . LEU B 2 132 ? 137.637 174.738 132.820 1.00 91.48  ? 154 LEU B CA  1 
ATOM   2345  C C   . LEU B 2 132 ? 138.181 173.881 133.953 1.00 91.48  ? 154 LEU B C   1 
ATOM   2346  O O   . LEU B 2 132 ? 138.446 172.688 133.788 1.00 91.48  ? 154 LEU B O   1 
ATOM   2347  C CB  . LEU B 2 132 ? 136.160 175.077 133.061 1.00 91.48  ? 154 LEU B CB  1 
ATOM   2348  C CG  . LEU B 2 132 ? 135.543 176.150 132.162 1.00 91.48  ? 154 LEU B CG  1 
ATOM   2349  C CD1 . LEU B 2 132 ? 134.045 176.254 132.398 1.00 91.48  ? 154 LEU B CD1 1 
ATOM   2350  C CD2 . LEU B 2 132 ? 136.218 177.491 132.394 1.00 91.48  ? 154 LEU B CD2 1 
ATOM   2351  N N   . GLU B 2 133 ? 138.347 174.505 135.117 1.00 91.68  ? 155 GLU B N   1 
ATOM   2352  C CA  . GLU B 2 133 ? 138.821 173.788 136.293 1.00 91.68  ? 155 GLU B CA  1 
ATOM   2353  C C   . GLU B 2 133 ? 137.728 172.858 136.804 1.00 91.68  ? 155 GLU B C   1 
ATOM   2354  O O   . GLU B 2 133 ? 136.657 173.315 137.218 1.00 91.68  ? 155 GLU B O   1 
ATOM   2355  C CB  . GLU B 2 133 ? 139.243 174.774 137.380 1.00 91.68  ? 155 GLU B CB  1 
ATOM   2356  C CG  . GLU B 2 133 ? 139.932 174.131 138.573 1.00 91.68  ? 155 GLU B CG  1 
ATOM   2357  C CD  . GLU B 2 133 ? 141.256 173.486 138.210 1.00 91.68  ? 155 GLU B CD  1 
ATOM   2358  O OE1 . GLU B 2 133 ? 141.255 172.305 137.805 1.00 91.68  ? 155 GLU B OE1 1 
ATOM   2359  O OE2 . GLU B 2 133 ? 142.300 174.162 138.329 1.00 91.68  ? 155 GLU B OE2 1 
ATOM   2360  N N   . THR B 2 134 ? 137.995 171.555 136.776 1.00 87.97  ? 156 THR B N   1 
ATOM   2361  C CA  . THR B 2 134 ? 137.030 170.545 137.188 1.00 87.97  ? 156 THR B CA  1 
ATOM   2362  C C   . THR B 2 134 ? 137.684 169.601 138.185 1.00 87.97  ? 156 THR B C   1 
ATOM   2363  O O   . THR B 2 134 ? 138.773 169.079 137.926 1.00 87.97  ? 156 THR B O   1 
ATOM   2364  C CB  . THR B 2 134 ? 136.502 169.759 135.983 1.00 87.97  ? 156 THR B CB  1 
ATOM   2365  O OG1 . THR B 2 134 ? 135.892 170.661 135.052 1.00 87.97  ? 156 THR B OG1 1 
ATOM   2366  C CG2 . THR B 2 134 ? 135.477 168.728 136.425 1.00 87.97  ? 156 THR B CG2 1 
ATOM   2367  N N   . ASN B 2 135 ? 137.021 169.386 139.317 1.00 78.68  ? 157 ASN B N   1 
ATOM   2368  C CA  . ASN B 2 135 ? 137.503 168.491 140.358 1.00 78.68  ? 157 ASN B CA  1 
ATOM   2369  C C   . ASN B 2 135 ? 136.671 167.216 140.373 1.00 78.68  ? 157 ASN B C   1 
ATOM   2370  O O   . ASN B 2 135 ? 135.443 167.262 140.253 1.00 78.68  ? 157 ASN B O   1 
ATOM   2371  C CB  . ASN B 2 135 ? 137.446 169.161 141.733 1.00 78.68  ? 157 ASN B CB  1 
ATOM   2372  C CG  . ASN B 2 135 ? 138.310 170.402 141.813 1.00 78.68  ? 157 ASN B CG  1 
ATOM   2373  O OD1 . ASN B 2 135 ? 139.234 170.583 141.021 1.00 78.68  ? 157 ASN B OD1 1 
ATOM   2374  N ND2 . ASN B 2 135 ? 138.012 171.266 142.776 1.00 78.68  ? 157 ASN B ND2 1 
ATOM   2375  N N   . TYR B 2 136 ? 137.346 166.080 140.524 1.00 67.17  ? 158 TYR B N   1 
ATOM   2376  C CA  . TYR B 2 136 ? 136.702 164.775 140.586 1.00 67.17  ? 158 TYR B CA  1 
ATOM   2377  C C   . TYR B 2 136 ? 136.890 164.201 141.984 1.00 67.17  ? 158 TYR B C   1 
ATOM   2378  O O   . TYR B 2 136 ? 138.026 164.008 142.431 1.00 67.17  ? 158 TYR B O   1 
ATOM   2379  C CB  . TYR B 2 136 ? 137.276 163.829 139.532 1.00 67.17  ? 158 TYR B CB  1 
ATOM   2380  C CG  . TYR B 2 136 ? 136.882 164.176 138.114 1.00 67.17  ? 158 TYR B CG  1 
ATOM   2381  C CD1 . TYR B 2 136 ? 135.730 163.650 137.545 1.00 67.17  ? 158 TYR B CD1 1 
ATOM   2382  C CD2 . TYR B 2 136 ? 137.662 165.028 137.344 1.00 67.17  ? 158 TYR B CD2 1 
ATOM   2383  C CE1 . TYR B 2 136 ? 135.366 163.962 136.251 1.00 67.17  ? 158 TYR B CE1 1 
ATOM   2384  C CE2 . TYR B 2 136 ? 137.305 165.346 136.048 1.00 67.17  ? 158 TYR B CE2 1 
ATOM   2385  C CZ  . TYR B 2 136 ? 136.156 164.811 135.507 1.00 67.17  ? 158 TYR B CZ  1 
ATOM   2386  O OH  . TYR B 2 136 ? 135.795 165.124 134.217 1.00 67.17  ? 158 TYR B OH  1 
ATOM   2387  N N   . THR B 2 137 ? 135.780 163.930 142.667 1.00 61.89  ? 159 THR B N   1 
ATOM   2388  C CA  . THR B 2 137 ? 135.792 163.398 144.022 1.00 61.89  ? 159 THR B CA  1 
ATOM   2389  C C   . THR B 2 137 ? 135.182 162.004 144.019 1.00 61.89  ? 159 THR B C   1 
ATOM   2390  O O   . THR B 2 137 ? 134.089 161.802 143.481 1.00 61.89  ? 159 THR B O   1 
ATOM   2391  C CB  . THR B 2 137 ? 135.020 164.309 144.981 1.00 61.89  ? 159 THR B CB  1 
ATOM   2392  O OG1 . THR B 2 137 ? 135.566 165.633 144.928 1.00 61.89  ? 159 THR B OG1 1 
ATOM   2393  C CG2 . THR B 2 137 ? 135.116 163.787 146.406 1.00 61.89  ? 159 THR B CG2 1 
ATOM   2394  N N   . LEU B 2 138 ? 135.889 161.049 144.618 1.00 58.22  ? 160 LEU B N   1 
ATOM   2395  C CA  . LEU B 2 138 ? 135.443 159.663 144.689 1.00 58.22  ? 160 LEU B CA  1 
ATOM   2396  C C   . LEU B 2 138 ? 134.788 159.414 146.042 1.00 58.22  ? 160 LEU B C   1 
ATOM   2397  O O   . LEU B 2 138 ? 135.425 159.590 147.086 1.00 58.22  ? 160 LEU B O   1 
ATOM   2398  C CB  . LEU B 2 138 ? 136.612 158.703 144.475 1.00 58.22  ? 160 LEU B CB  1 
ATOM   2399  C CG  . LEU B 2 138 ? 136.289 157.211 144.558 1.00 58.22  ? 160 LEU B CG  1 
ATOM   2400  C CD1 . LEU B 2 138 ? 135.299 156.815 143.475 1.00 58.22  ? 160 LEU B CD1 1 
ATOM   2401  C CD2 . LEU B 2 138 ? 137.558 156.379 144.460 1.00 58.22  ? 160 LEU B CD2 1 
ATOM   2402  N N   . LYS B 2 139 ? 133.525 159.006 146.020 1.00 56.95  ? 161 LYS B N   1 
ATOM   2403  C CA  . LYS B 2 139 ? 132.774 158.700 147.227 1.00 56.95  ? 161 LYS B CA  1 
ATOM   2404  C C   . LYS B 2 139 ? 132.828 157.206 147.524 1.00 56.95  ? 161 LYS B C   1 
ATOM   2405  O O   . LYS B 2 139 ? 133.035 156.377 146.634 1.00 56.95  ? 161 LYS B O   1 
ATOM   2406  C CB  . LYS B 2 139 ? 131.319 159.155 147.090 1.00 56.95  ? 161 LYS B CB  1 
ATOM   2407  C CG  . LYS B 2 139 ? 131.148 160.660 146.988 1.00 56.95  ? 161 LYS B CG  1 
ATOM   2408  C CD  . LYS B 2 139 ? 131.579 161.351 148.269 1.00 56.95  ? 161 LYS B CD  1 
ATOM   2409  C CE  . LYS B 2 139 ? 131.344 162.850 148.192 1.00 56.95  ? 161 LYS B CE  1 
ATOM   2410  N NZ  . LYS B 2 139 ? 131.682 163.532 149.471 1.00 56.95  ? 161 LYS B NZ  1 
ATOM   2411  N N   . SER B 2 140 ? 132.635 156.870 148.797 1.00 58.54  ? 162 SER B N   1 
ATOM   2412  C CA  . SER B 2 140 ? 132.653 155.482 149.235 1.00 58.54  ? 162 SER B CA  1 
ATOM   2413  C C   . SER B 2 140 ? 131.951 155.384 150.579 1.00 58.54  ? 162 SER B C   1 
ATOM   2414  O O   . SER B 2 140 ? 132.157 156.229 151.454 1.00 58.54  ? 162 SER B O   1 
ATOM   2415  C CB  . SER B 2 140 ? 134.086 154.948 149.342 1.00 58.54  ? 162 SER B CB  1 
ATOM   2416  O OG  . SER B 2 140 ? 134.934 155.891 149.972 1.00 58.54  ? 162 SER B OG  1 
ATOM   2417  N N   . GLU B 2 141 ? 131.127 154.350 150.738 1.00 52.27  ? 163 GLU B N   1 
ATOM   2418  C CA  . GLU B 2 141 ? 130.385 154.163 151.976 1.00 52.27  ? 163 GLU B CA  1 
ATOM   2419  C C   . GLU B 2 141 ? 129.888 152.728 152.056 1.00 52.27  ? 163 GLU B C   1 
ATOM   2420  O O   . GLU B 2 141 ? 129.693 152.065 151.034 1.00 52.27  ? 163 GLU B O   1 
ATOM   2421  C CB  . GLU B 2 141 ? 129.203 155.135 152.075 1.00 52.27  ? 163 GLU B CB  1 
ATOM   2422  C CG  . GLU B 2 141 ? 128.079 154.843 151.097 1.00 52.27  ? 163 GLU B CG  1 
ATOM   2423  C CD  . GLU B 2 141 ? 126.834 155.659 151.380 1.00 52.27  ? 163 GLU B CD  1 
ATOM   2424  O OE1 . GLU B 2 141 ? 126.901 156.572 152.230 1.00 52.27  ? 163 GLU B OE1 1 
ATOM   2425  O OE2 . GLU B 2 141 ? 125.788 155.387 150.755 1.00 52.27  ? 163 GLU B OE2 1 
ATOM   2426  N N   . TRP B 2 142 ? 129.692 152.261 153.285 1.00 35.60  ? 164 TRP B N   1 
ATOM   2427  C CA  . TRP B 2 142 ? 129.090 150.962 153.540 1.00 35.60  ? 164 TRP B CA  1 
ATOM   2428  C C   . TRP B 2 142 ? 127.570 151.113 153.571 1.00 35.60  ? 164 TRP B C   1 
ATOM   2429  O O   . TRP B 2 142 ? 127.017 152.147 153.188 1.00 35.60  ? 164 TRP B O   1 
ATOM   2430  C CB  . TRP B 2 142 ? 129.615 150.375 154.847 1.00 35.60  ? 164 TRP B CB  1 
ATOM   2431  C CG  . TRP B 2 142 ? 130.980 149.780 154.752 1.00 35.60  ? 164 TRP B CG  1 
ATOM   2432  C CD1 . TRP B 2 142 ? 131.742 149.647 153.630 1.00 35.60  ? 164 TRP B CD1 1 
ATOM   2433  C CD2 . TRP B 2 142 ? 131.750 149.231 155.827 1.00 35.60  ? 164 TRP B CD2 1 
ATOM   2434  N NE1 . TRP B 2 142 ? 132.940 149.050 153.939 1.00 35.60  ? 164 TRP B NE1 1 
ATOM   2435  C CE2 . TRP B 2 142 ? 132.969 148.785 155.283 1.00 35.60  ? 164 TRP B CE2 1 
ATOM   2436  C CE3 . TRP B 2 142 ? 131.526 149.074 157.198 1.00 35.60  ? 164 TRP B CE3 1 
ATOM   2437  C CZ2 . TRP B 2 142 ? 133.961 148.193 156.061 1.00 35.60  ? 164 TRP B CZ2 1 
ATOM   2438  C CZ3 . TRP B 2 142 ? 132.512 148.487 157.968 1.00 35.60  ? 164 TRP B CZ3 1 
ATOM   2439  C CH2 . TRP B 2 142 ? 133.714 148.053 157.398 1.00 35.60  ? 164 TRP B CH2 1 
ATOM   2440  N N   . ALA B 2 143 ? 126.876 150.073 154.032 1.00 45.29  ? 165 ALA B N   1 
ATOM   2441  C CA  . ALA B 2 143 ? 125.437 150.168 154.233 1.00 45.29  ? 165 ALA B CA  1 
ATOM   2442  C C   . ALA B 2 143 ? 125.075 150.921 155.505 1.00 45.29  ? 165 ALA B C   1 
ATOM   2443  O O   . ALA B 2 143 ? 123.934 151.377 155.635 1.00 45.29  ? 165 ALA B O   1 
ATOM   2444  C CB  . ALA B 2 143 ? 124.814 148.772 154.266 1.00 45.29  ? 165 ALA B CB  1 
ATOM   2445  N N   . THR B 2 144 ? 126.014 151.060 156.443 1.00 45.39  ? 166 THR B N   1 
ATOM   2446  C CA  . THR B 2 144 ? 125.750 151.761 157.692 1.00 45.39  ? 166 THR B CA  1 
ATOM   2447  C C   . THR B 2 144 ? 126.857 152.721 158.106 1.00 45.39  ? 166 THR B C   1 
ATOM   2448  O O   . THR B 2 144 ? 126.733 153.352 159.160 1.00 45.39  ? 166 THR B O   1 
ATOM   2449  C CB  . THR B 2 144 ? 125.512 150.758 158.834 1.00 45.39  ? 166 THR B CB  1 
ATOM   2450  O OG1 . THR B 2 144 ? 126.525 149.745 158.803 1.00 45.39  ? 166 THR B OG1 1 
ATOM   2451  C CG2 . THR B 2 144 ? 124.144 150.109 158.703 1.00 45.39  ? 166 THR B CG2 1 
ATOM   2452  N N   . GLU B 2 145 ? 127.927 152.854 157.326 1.00 53.29  ? 167 GLU B N   1 
ATOM   2453  C CA  . GLU B 2 145 ? 129.032 153.733 157.676 1.00 53.29  ? 167 GLU B CA  1 
ATOM   2454  C C   . GLU B 2 145 ? 129.571 154.393 156.417 1.00 53.29  ? 167 GLU B C   1 
ATOM   2455  O O   . GLU B 2 145 ? 129.466 153.845 155.317 1.00 53.29  ? 167 GLU B O   1 
ATOM   2456  C CB  . GLU B 2 145 ? 130.153 152.969 158.394 1.00 53.29  ? 167 GLU B CB  1 
ATOM   2457  C CG  . GLU B 2 145 ? 131.069 153.847 159.232 1.00 53.29  ? 167 GLU B CG  1 
ATOM   2458  C CD  . GLU B 2 145 ? 132.232 153.077 159.826 1.00 53.29  ? 167 GLU B CD  1 
ATOM   2459  O OE1 . GLU B 2 145 ? 132.739 152.154 159.155 1.00 53.29  ? 167 GLU B OE1 1 
ATOM   2460  O OE2 . GLU B 2 145 ? 132.639 153.396 160.963 1.00 53.29  ? 167 GLU B OE2 1 
ATOM   2461  N N   . LYS B 2 146 ? 130.151 155.577 156.590 1.00 59.08  ? 168 LYS B N   1 
ATOM   2462  C CA  . LYS B 2 146 ? 130.711 156.346 155.491 1.00 59.08  ? 168 LYS B CA  1 
ATOM   2463  C C   . LYS B 2 146 ? 132.220 156.464 155.654 1.00 59.08  ? 168 LYS B C   1 
ATOM   2464  O O   . LYS B 2 146 ? 132.746 156.434 156.771 1.00 59.08  ? 168 LYS B O   1 
ATOM   2465  C CB  . LYS B 2 146 ? 130.082 157.741 155.411 1.00 59.08  ? 168 LYS B CB  1 
ATOM   2466  C CG  . LYS B 2 146 ? 128.581 157.727 155.179 1.00 59.08  ? 168 LYS B CG  1 
ATOM   2467  C CD  . LYS B 2 146 ? 128.027 159.137 155.063 1.00 59.08  ? 168 LYS B CD  1 
ATOM   2468  C CE  . LYS B 2 146 ? 126.522 159.123 154.858 1.00 59.08  ? 168 LYS B CE  1 
ATOM   2469  N NZ  . LYS B 2 146 ? 126.137 158.386 153.623 1.00 59.08  ? 168 LYS B NZ  1 
ATOM   2470  N N   . PHE B 2 147 ? 132.910 156.600 154.530 1.00 61.52  ? 169 PHE B N   1 
ATOM   2471  C CA  . PHE B 2 147 ? 134.360 156.676 154.481 1.00 61.52  ? 169 PHE B CA  1 
ATOM   2472  C C   . PHE B 2 147 ? 134.817 158.035 153.962 1.00 61.52  ? 169 PHE B C   1 
ATOM   2473  O O   . PHE B 2 147 ? 134.053 158.749 153.304 1.00 61.52  ? 169 PHE B O   1 
ATOM   2474  C CB  . PHE B 2 147 ? 134.919 155.564 153.583 1.00 61.52  ? 169 PHE B CB  1 
ATOM   2475  C CG  . PHE B 2 147 ? 134.913 154.207 154.226 1.00 61.52  ? 169 PHE B CG  1 
ATOM   2476  C CD1 . PHE B 2 147 ? 136.071 153.680 154.769 1.00 61.52  ? 169 PHE B CD1 1 
ATOM   2477  C CD2 . PHE B 2 147 ? 133.748 153.462 154.291 1.00 61.52  ? 169 PHE B CD2 1 
ATOM   2478  C CE1 . PHE B 2 147 ? 136.069 152.433 155.362 1.00 61.52  ? 169 PHE B CE1 1 
ATOM   2479  C CE2 . PHE B 2 147 ? 133.740 152.214 154.883 1.00 61.52  ? 169 PHE B CE2 1 
ATOM   2480  C CZ  . PHE B 2 147 ? 134.903 151.699 155.419 1.00 61.52  ? 169 PHE B CZ  1 
ATOM   2481  N N   . PRO B 2 148 ? 136.057 158.433 154.253 1.00 68.08  ? 170 PRO B N   1 
ATOM   2482  C CA  . PRO B 2 148 ? 136.562 159.710 153.736 1.00 68.08  ? 170 PRO B CA  1 
ATOM   2483  C C   . PRO B 2 148 ? 136.583 159.737 152.215 1.00 68.08  ? 170 PRO B C   1 
ATOM   2484  O O   . PRO B 2 148 ? 136.585 158.704 151.542 1.00 68.08  ? 170 PRO B O   1 
ATOM   2485  C CB  . PRO B 2 148 ? 137.980 159.793 154.313 1.00 68.08  ? 170 PRO B CB  1 
ATOM   2486  C CG  . PRO B 2 148 ? 137.941 158.934 155.528 1.00 68.08  ? 170 PRO B CG  1 
ATOM   2487  C CD  . PRO B 2 148 ? 137.000 157.813 155.201 1.00 68.08  ? 170 PRO B CD  1 
ATOM   2488  N N   . ASP B 2 149 ? 136.606 160.951 151.676 1.00 63.81  ? 171 ASP B N   1 
ATOM   2489  C CA  . ASP B 2 149 ? 136.531 161.159 150.239 1.00 63.81  ? 171 ASP B CA  1 
ATOM   2490  C C   . ASP B 2 149 ? 137.912 161.093 149.599 1.00 63.81  ? 171 ASP B C   1 
ATOM   2491  O O   . ASP B 2 149 ? 138.924 161.445 150.211 1.00 63.81  ? 171 ASP B O   1 
ATOM   2492  C CB  . ASP B 2 149 ? 135.883 162.507 149.926 1.00 63.81  ? 171 ASP B CB  1 
ATOM   2493  C CG  . ASP B 2 149 ? 134.569 162.699 150.650 1.00 63.81  ? 171 ASP B CG  1 
ATOM   2494  O OD1 . ASP B 2 149 ? 133.898 161.688 150.943 1.00 63.81  ? 171 ASP B OD1 1 
ATOM   2495  O OD2 . ASP B 2 149 ? 134.205 163.861 150.924 1.00 63.81  ? 171 ASP B OD2 1 
ATOM   2496  N N   . CYS B 2 150 ? 137.939 160.638 148.351 1.00 71.90  ? 172 CYS B N   1 
ATOM   2497  C CA  . CYS B 2 150 ? 139.163 160.535 147.561 1.00 71.90  ? 172 CYS B CA  1 
ATOM   2498  C C   . CYS B 2 150 ? 139.134 161.658 146.530 1.00 71.90  ? 172 CYS B C   1 
ATOM   2499  O O   . CYS B 2 150 ? 138.443 161.560 145.512 1.00 71.90  ? 172 CYS B O   1 
ATOM   2500  C CB  . CYS B 2 150 ? 139.264 159.164 146.898 1.00 71.90  ? 172 CYS B CB  1 
ATOM   2501  S SG  . CYS B 2 150 ? 140.924 158.650 146.370 1.00 71.90  ? 172 CYS B SG  1 
ATOM   2502  N N   . GLN B 2 151 ? 139.885 162.724 146.797 1.00 80.65  ? 173 GLN B N   1 
ATOM   2503  C CA  . GLN B 2 151 ? 139.973 163.856 145.883 1.00 80.65  ? 173 GLN B CA  1 
ATOM   2504  C C   . GLN B 2 151 ? 141.120 163.622 144.907 1.00 80.65  ? 173 GLN B C   1 
ATOM   2505  O O   . GLN B 2 151 ? 142.270 163.448 145.323 1.00 80.65  ? 173 GLN B O   1 
ATOM   2506  C CB  . GLN B 2 151 ? 140.174 165.163 146.648 1.00 80.65  ? 173 GLN B CB  1 
ATOM   2507  C CG  . GLN B 2 151 ? 140.114 166.396 145.762 1.00 80.65  ? 173 GLN B CG  1 
ATOM   2508  C CD  . GLN B 2 151 ? 140.048 167.685 146.555 1.00 80.65  ? 173 GLN B CD  1 
ATOM   2509  O OE1 . GLN B 2 151 ? 140.011 167.669 147.784 1.00 80.65  ? 173 GLN B OE1 1 
ATOM   2510  N NE2 . GLN B 2 151 ? 140.031 168.813 145.852 1.00 80.65  ? 173 GLN B NE2 1 
ATOM   2511  N N   . SER B 2 152 ? 140.803 163.619 143.614 1.00 94.11  ? 174 SER B N   1 
ATOM   2512  C CA  . SER B 2 152 ? 141.799 163.371 142.576 1.00 94.11  ? 174 SER B CA  1 
ATOM   2513  C C   . SER B 2 152 ? 142.805 164.514 142.546 1.00 94.11  ? 174 SER B C   1 
ATOM   2514  O O   . SER B 2 152 ? 142.459 165.647 142.197 1.00 94.11  ? 174 SER B O   1 
ATOM   2515  C CB  . SER B 2 152 ? 141.118 163.212 141.221 1.00 94.11  ? 174 SER B CB  1 
ATOM   2516  O OG  . SER B 2 152 ? 140.132 164.210 141.025 1.00 94.11  ? 174 SER B OG  1 
ATOM   2517  N N   . LYS B 2 153 ? 144.056 164.219 142.908 1.00 97.74  ? 175 LYS B N   1 
ATOM   2518  C CA  . LYS B 2 153 ? 145.091 165.247 142.885 1.00 97.74  ? 175 LYS B CA  1 
ATOM   2519  C C   . LYS B 2 153 ? 145.499 165.588 141.458 1.00 97.74  ? 175 LYS B C   1 
ATOM   2520  O O   . LYS B 2 153 ? 145.774 166.753 141.145 1.00 97.74  ? 175 LYS B O   1 
ATOM   2521  C CB  . LYS B 2 153 ? 146.302 164.786 143.696 1.00 97.74  ? 175 LYS B CB  1 
ATOM   2522  C CG  . LYS B 2 153 ? 147.363 165.856 143.896 1.00 97.74  ? 175 LYS B CG  1 
ATOM   2523  C CD  . LYS B 2 153 ? 148.738 165.238 144.092 1.00 97.74  ? 175 LYS B CD  1 
ATOM   2524  C CE  . LYS B 2 153 ? 149.190 164.490 142.849 1.00 97.74  ? 175 LYS B CE  1 
ATOM   2525  N NZ  . LYS B 2 153 ? 149.404 165.406 141.696 1.00 97.74  ? 175 LYS B NZ  1 
ATOM   2526  N N   . HIS B 2 154 ? 145.542 164.589 140.580 1.00 99.71  ? 176 HIS B N   1 
ATOM   2527  C CA  . HIS B 2 154 ? 145.911 164.803 139.189 1.00 99.71  ? 176 HIS B CA  1 
ATOM   2528  C C   . HIS B 2 154 ? 145.391 163.640 138.357 1.00 99.71  ? 176 HIS B C   1 
ATOM   2529  O O   . HIS B 2 154 ? 145.459 162.485 138.785 1.00 99.71  ? 176 HIS B O   1 
ATOM   2530  C CB  . HIS B 2 154 ? 147.429 164.938 139.028 1.00 99.71  ? 176 HIS B CB  1 
ATOM   2531  C CG  . HIS B 2 154 ? 147.894 164.845 137.609 1.00 99.71  ? 176 HIS B CG  1 
ATOM   2532  N ND1 . HIS B 2 154 ? 147.500 165.739 136.636 1.00 99.71  ? 176 HIS B ND1 1 
ATOM   2533  C CD2 . HIS B 2 154 ? 148.717 163.961 136.997 1.00 99.71  ? 176 HIS B CD2 1 
ATOM   2534  C CE1 . HIS B 2 154 ? 148.063 165.411 135.487 1.00 99.71  ? 176 HIS B CE1 1 
ATOM   2535  N NE2 . HIS B 2 154 ? 148.805 164.336 135.678 1.00 99.71  ? 176 HIS B NE2 1 
ATOM   2536  N N   . GLY B 2 155 ? 144.872 163.955 137.174 1.00 95.61  ? 177 GLY B N   1 
ATOM   2537  C CA  . GLY B 2 155 ? 144.376 162.937 136.270 1.00 95.61  ? 177 GLY B CA  1 
ATOM   2538  C C   . GLY B 2 155 ? 143.014 162.394 136.646 1.00 95.61  ? 177 GLY B C   1 
ATOM   2539  O O   . GLY B 2 155 ? 142.104 163.154 136.994 1.00 95.61  ? 177 GLY B O   1 
ATOM   2540  N N   . THR B 2 156 ? 142.863 161.069 136.580 1.00 78.97  ? 178 THR B N   1 
ATOM   2541  C CA  . THR B 2 156 ? 141.596 160.415 136.862 1.00 78.97  ? 178 THR B CA  1 
ATOM   2542  C C   . THR B 2 156 ? 141.670 159.351 137.947 1.00 78.97  ? 178 THR B C   1 
ATOM   2543  O O   . THR B 2 156 ? 140.637 159.049 138.554 1.00 78.97  ? 178 THR B O   1 
ATOM   2544  C CB  . THR B 2 156 ? 141.028 159.768 135.588 1.00 78.97  ? 178 THR B CB  1 
ATOM   2545  O OG1 . THR B 2 156 ? 141.963 158.809 135.076 1.00 78.97  ? 178 THR B OG1 1 
ATOM   2546  C CG2 . THR B 2 156 ? 140.767 160.827 134.525 1.00 78.97  ? 178 THR B CG2 1 
ATOM   2547  N N   . SER B 2 157 ? 142.839 158.774 138.203 1.00 73.07  ? 179 SER B N   1 
ATOM   2548  C CA  . SER B 2 157 ? 142.965 157.756 139.236 1.00 73.07  ? 179 SER B CA  1 
ATOM   2549  C C   . SER B 2 157 ? 143.089 158.399 140.611 1.00 73.07  ? 179 SER B C   1 
ATOM   2550  O O   . SER B 2 157 ? 143.690 159.466 140.761 1.00 73.07  ? 179 SER B O   1 
ATOM   2551  C CB  . SER B 2 157 ? 144.179 156.867 138.967 1.00 73.07  ? 179 SER B CB  1 
ATOM   2552  O OG  . SER B 2 157 ? 145.309 157.636 138.594 1.00 73.07  ? 179 SER B OG  1 
ATOM   2553  N N   . CYS B 2 158 ? 142.520 157.741 141.619 1.00 73.27  ? 180 CYS B N   1 
ATOM   2554  C CA  . CYS B 2 158 ? 142.585 158.231 142.990 1.00 73.27  ? 180 CYS B CA  1 
ATOM   2555  C C   . CYS B 2 158 ? 142.723 157.040 143.925 1.00 73.27  ? 180 CYS B C   1 
ATOM   2556  O O   . CYS B 2 158 ? 141.945 156.087 143.835 1.00 73.27  ? 180 CYS B O   1 
ATOM   2557  C CB  . CYS B 2 158 ? 141.339 159.050 143.354 1.00 73.27  ? 180 CYS B CB  1 
ATOM   2558  S SG  . CYS B 2 158 ? 141.458 159.965 144.915 1.00 73.27  ? 180 CYS B SG  1 
ATOM   2559  N N   . MET B 2 159 ? 143.701 157.103 144.824 1.00 67.36  ? 181 MET B N   1 
ATOM   2560  C CA  . MET B 2 159 ? 143.976 156.024 145.764 1.00 67.36  ? 181 MET B CA  1 
ATOM   2561  C C   . MET B 2 159 ? 143.406 156.379 147.130 1.00 67.36  ? 181 MET B C   1 
ATOM   2562  O O   . MET B 2 159 ? 143.722 157.437 147.684 1.00 67.36  ? 181 MET B O   1 
ATOM   2563  C CB  . MET B 2 159 ? 145.480 155.765 145.866 1.00 67.36  ? 181 MET B CB  1 
ATOM   2564  C CG  . MET B 2 159 ? 145.858 154.586 146.743 1.00 67.36  ? 181 MET B CG  1 
ATOM   2565  S SD  . MET B 2 159 ? 147.637 154.305 146.757 1.00 67.36  ? 181 MET B SD  1 
ATOM   2566  C CE  . MET B 2 159 ? 147.748 152.886 147.839 1.00 67.36  ? 181 MET B CE  1 
ATOM   2567  N N   . VAL B 2 160 ? 142.561 155.494 147.667 1.00 66.21  ? 182 VAL B N   1 
ATOM   2568  C CA  . VAL B 2 160 ? 141.936 155.756 148.958 1.00 66.21  ? 182 VAL B CA  1 
ATOM   2569  C C   . VAL B 2 160 ? 142.982 155.706 150.068 1.00 66.21  ? 182 VAL B C   1 
ATOM   2570  O O   . VAL B 2 160 ? 144.095 155.194 149.902 1.00 66.21  ? 182 VAL B O   1 
ATOM   2571  C CB  . VAL B 2 160 ? 140.793 154.765 149.228 1.00 66.21  ? 182 VAL B CB  1 
ATOM   2572  C CG1 . VAL B 2 160 ? 139.729 154.871 148.145 1.00 66.21  ? 182 VAL B CG1 1 
ATOM   2573  C CG2 . VAL B 2 160 ? 141.334 153.347 149.321 1.00 66.21  ? 182 VAL B CG2 1 
ATOM   2574  N N   . SER B 2 161 ? 142.610 156.254 151.226 1.00 71.44  ? 183 SER B N   1 
ATOM   2575  C CA  . SER B 2 161 ? 143.515 156.343 152.362 1.00 71.44  ? 183 SER B CA  1 
ATOM   2576  C C   . SER B 2 161 ? 143.266 155.279 153.422 1.00 71.44  ? 183 SER B C   1 
ATOM   2577  O O   . SER B 2 161 ? 144.170 154.999 154.215 1.00 71.44  ? 183 SER B O   1 
ATOM   2578  C CB  . SER B 2 161 ? 143.414 157.729 153.012 1.00 71.44  ? 183 SER B CB  1 
ATOM   2579  O OG  . SER B 2 161 ? 142.073 158.038 153.347 1.00 71.44  ? 183 SER B OG  1 
ATOM   2580  N N   . TYR B 2 162 ? 142.079 154.684 153.455 1.00 69.36  ? 184 TYR B N   1 
ATOM   2581  C CA  . TYR B 2 162 ? 141.752 153.683 154.457 1.00 69.36  ? 184 TYR B CA  1 
ATOM   2582  C C   . TYR B 2 162 ? 142.161 152.292 153.984 1.00 69.36  ? 184 TYR B C   1 
ATOM   2583  O O   . TYR B 2 162 ? 142.411 152.056 152.800 1.00 69.36  ? 184 TYR B O   1 
ATOM   2584  C CB  . TYR B 2 162 ? 140.257 153.708 154.782 1.00 69.36  ? 184 TYR B CB  1 
ATOM   2585  C CG  . TYR B 2 162 ? 139.358 153.615 153.569 1.00 69.36  ? 184 TYR B CG  1 
ATOM   2586  C CD1 . TYR B 2 162 ? 138.913 154.759 152.921 1.00 69.36  ? 184 TYR B CD1 1 
ATOM   2587  C CD2 . TYR B 2 162 ? 138.951 152.383 153.074 1.00 69.36  ? 184 TYR B CD2 1 
ATOM   2588  C CE1 . TYR B 2 162 ? 138.092 154.680 151.813 1.00 69.36  ? 184 TYR B CE1 1 
ATOM   2589  C CE2 . TYR B 2 162 ? 138.130 152.294 151.966 1.00 69.36  ? 184 TYR B CE2 1 
ATOM   2590  C CZ  . TYR B 2 162 ? 137.704 153.445 151.340 1.00 69.36  ? 184 TYR B CZ  1 
ATOM   2591  O OH  . TYR B 2 162 ? 136.886 153.360 150.237 1.00 69.36  ? 184 TYR B OH  1 
ATOM   2592  N N   . MET B 2 163 ? 142.227 151.364 154.936 1.00 67.17  ? 185 MET B N   1 
ATOM   2593  C CA  . MET B 2 163 ? 142.584 149.990 154.612 1.00 67.17  ? 185 MET B CA  1 
ATOM   2594  C C   . MET B 2 163 ? 141.347 149.220 154.151 1.00 67.17  ? 185 MET B C   1 
ATOM   2595  O O   . MET B 2 163 ? 140.257 149.411 154.697 1.00 67.17  ? 185 MET B O   1 
ATOM   2596  C CB  . MET B 2 163 ? 143.207 149.296 155.820 1.00 67.17  ? 185 MET B CB  1 
ATOM   2597  C CG  . MET B 2 163 ? 144.546 149.876 156.243 1.00 67.17  ? 185 MET B CG  1 
ATOM   2598  S SD  . MET B 2 163 ? 145.788 149.765 154.941 1.00 67.17  ? 185 MET B SD  1 
ATOM   2599  C CE  . MET B 2 163 ? 147.205 150.488 155.762 1.00 67.17  ? 185 MET B CE  1 
ATOM   2600  N N   . PRO B 2 164 ? 141.485 148.351 153.151 1.00 58.71  ? 186 PRO B N   1 
ATOM   2601  C CA  . PRO B 2 164 ? 140.315 147.627 152.636 1.00 58.71  ? 186 PRO B CA  1 
ATOM   2602  C C   . PRO B 2 164 ? 139.859 146.551 153.610 1.00 58.71  ? 186 PRO B C   1 
ATOM   2603  O O   . PRO B 2 164 ? 140.672 145.809 154.166 1.00 58.71  ? 186 PRO B O   1 
ATOM   2604  C CB  . PRO B 2 164 ? 140.823 147.022 151.323 1.00 58.71  ? 186 PRO B CB  1 
ATOM   2605  C CG  . PRO B 2 164 ? 142.291 146.867 151.534 1.00 58.71  ? 186 PRO B CG  1 
ATOM   2606  C CD  . PRO B 2 164 ? 142.717 148.011 152.417 1.00 58.71  ? 186 PRO B CD  1 
ATOM   2607  N N   . THR B 2 165 ? 138.547 146.474 153.816 1.00 52.16  ? 187 THR B N   1 
ATOM   2608  C CA  . THR B 2 165 ? 137.931 145.454 154.652 1.00 52.16  ? 187 THR B CA  1 
ATOM   2609  C C   . THR B 2 165 ? 137.215 144.450 153.760 1.00 52.16  ? 187 THR B C   1 
ATOM   2610  O O   . THR B 2 165 ? 136.386 144.833 152.928 1.00 52.16  ? 187 THR B O   1 
ATOM   2611  C CB  . THR B 2 165 ? 136.949 146.073 155.648 1.00 52.16  ? 187 THR B CB  1 
ATOM   2612  O OG1 . THR B 2 165 ? 137.639 147.015 156.478 1.00 52.16  ? 187 THR B OG1 1 
ATOM   2613  C CG2 . THR B 2 165 ? 136.329 144.995 156.523 1.00 52.16  ? 187 THR B CG2 1 
ATOM   2614  N N   . TYR B 2 166 ? 137.535 143.172 153.935 1.00 41.62  ? 188 TYR B N   1 
ATOM   2615  C CA  . TYR B 2 166 ? 137.004 142.124 153.080 1.00 41.62  ? 188 TYR B CA  1 
ATOM   2616  C C   . TYR B 2 166 ? 135.659 141.622 153.601 1.00 41.62  ? 188 TYR B C   1 
ATOM   2617  O O   . TYR B 2 166 ? 135.263 141.882 154.739 1.00 41.62  ? 188 TYR B O   1 
ATOM   2618  C CB  . TYR B 2 166 ? 138.002 140.972 152.972 1.00 41.62  ? 188 TYR B CB  1 
ATOM   2619  C CG  . TYR B 2 166 ? 139.364 141.397 152.473 1.00 41.62  ? 188 TYR B CG  1 
ATOM   2620  C CD1 . TYR B 2 166 ? 139.626 141.492 151.113 1.00 41.62  ? 188 TYR B CD1 1 
ATOM   2621  C CD2 . TYR B 2 166 ? 140.385 141.708 153.360 1.00 41.62  ? 188 TYR B CD2 1 
ATOM   2622  C CE1 . TYR B 2 166 ? 140.868 141.883 150.651 1.00 41.62  ? 188 TYR B CE1 1 
ATOM   2623  C CE2 . TYR B 2 166 ? 141.630 142.099 152.907 1.00 41.62  ? 188 TYR B CE2 1 
ATOM   2624  C CZ  . TYR B 2 166 ? 141.865 142.184 151.552 1.00 41.62  ? 188 TYR B CZ  1 
ATOM   2625  O OH  . TYR B 2 166 ? 143.103 142.574 151.095 1.00 41.62  ? 188 TYR B OH  1 
ATOM   2626  N N   . TYR B 2 167 ? 134.950 140.898 152.733 1.00 40.26  ? 189 TYR B N   1 
ATOM   2627  C CA  . TYR B 2 167 ? 133.662 140.278 153.040 1.00 40.26  ? 189 TYR B CA  1 
ATOM   2628  C C   . TYR B 2 167 ? 132.594 141.297 153.428 1.00 40.26  ? 189 TYR B C   1 
ATOM   2629  O O   . TYR B 2 167 ? 131.642 140.960 154.138 1.00 40.26  ? 189 TYR B O   1 
ATOM   2630  C CB  . TYR B 2 167 ? 133.801 139.219 154.140 1.00 40.26  ? 189 TYR B CB  1 
ATOM   2631  C CG  . TYR B 2 167 ? 134.864 138.182 153.860 1.00 40.26  ? 189 TYR B CG  1 
ATOM   2632  C CD1 . TYR B 2 167 ? 134.610 137.113 153.012 1.00 40.26  ? 189 TYR B CD1 1 
ATOM   2633  C CD2 . TYR B 2 167 ? 136.119 138.271 154.445 1.00 40.26  ? 189 TYR B CD2 1 
ATOM   2634  C CE1 . TYR B 2 167 ? 135.577 136.163 152.753 1.00 40.26  ? 189 TYR B CE1 1 
ATOM   2635  C CE2 . TYR B 2 167 ? 137.093 137.324 154.192 1.00 40.26  ? 189 TYR B CE2 1 
ATOM   2636  C CZ  . TYR B 2 167 ? 136.816 136.273 153.345 1.00 40.26  ? 189 TYR B CZ  1 
ATOM   2637  O OH  . TYR B 2 167 ? 137.782 135.327 153.090 1.00 40.26  ? 189 TYR B OH  1 
ATOM   2638  N N   . VAL B 2 168 ? 132.728 142.542 152.976 1.00 38.14  ? 190 VAL B N   1 
ATOM   2639  C CA  . VAL B 2 168 ? 131.756 143.593 153.254 1.00 38.14  ? 190 VAL B CA  1 
ATOM   2640  C C   . VAL B 2 168 ? 131.499 144.354 151.962 1.00 38.14  ? 190 VAL B C   1 
ATOM   2641  O O   . VAL B 2 168 ? 132.424 144.946 151.393 1.00 38.14  ? 190 VAL B O   1 
ATOM   2642  C CB  . VAL B 2 168 ? 132.236 144.551 154.357 1.00 38.14  ? 190 VAL B CB  1 
ATOM   2643  C CG1 . VAL B 2 168 ? 131.334 145.771 154.425 1.00 38.14  ? 190 VAL B CG1 1 
ATOM   2644  C CG2 . VAL B 2 168 ? 132.272 143.840 155.701 1.00 38.14  ? 190 VAL B CG2 1 
ATOM   2645  N N   . ASN B 2 169 ? 130.250 144.343 151.502 1.00 39.53  ? 191 ASN B N   1 
ATOM   2646  C CA  . ASN B 2 169 ? 129.899 145.034 150.270 1.00 39.53  ? 191 ASN B CA  1 
ATOM   2647  C C   . ASN B 2 169 ? 130.052 146.540 150.437 1.00 39.53  ? 191 ASN B C   1 
ATOM   2648  O O   . ASN B 2 169 ? 129.634 147.117 151.444 1.00 39.53  ? 191 ASN B O   1 
ATOM   2649  C CB  . ASN B 2 169 ? 128.467 144.697 149.860 1.00 39.53  ? 191 ASN B CB  1 
ATOM   2650  C CG  . ASN B 2 169 ? 128.295 143.240 149.483 1.00 39.53  ? 191 ASN B CG  1 
ATOM   2651  O OD1 . ASN B 2 169 ? 127.527 142.512 150.110 1.00 39.53  ? 191 ASN B OD1 1 
ATOM   2652  N ND2 . ASN B 2 169 ? 129.011 142.807 148.453 1.00 39.53  ? 191 ASN B ND2 1 
ATOM   2653  N N   . ILE B 2 170 ? 130.657 147.177 149.438 1.00 39.13  ? 192 ILE B N   1 
ATOM   2654  C CA  . ILE B 2 170 ? 130.899 148.614 149.444 1.00 39.13  ? 192 ILE B CA  1 
ATOM   2655  C C   . ILE B 2 170 ? 130.380 149.197 148.137 1.00 39.13  ? 192 ILE B C   1 
ATOM   2656  O O   . ILE B 2 170 ? 130.473 148.560 147.082 1.00 39.13  ? 192 ILE B O   1 
ATOM   2657  C CB  . ILE B 2 170 ? 132.397 148.934 149.644 1.00 39.13  ? 192 ILE B CB  1 
ATOM   2658  C CG1 . ILE B 2 170 ? 132.633 150.444 149.698 1.00 39.13  ? 192 ILE B CG1 1 
ATOM   2659  C CG2 . ILE B 2 170 ? 133.239 148.292 148.552 1.00 39.13  ? 192 ILE B CG2 1 
ATOM   2660  C CD1 . ILE B 2 170 ? 134.081 150.825 149.911 1.00 39.13  ? 192 ILE B CD1 1 
ATOM   2661  N N   . GLU B 2 171 ? 129.817 150.401 148.210 1.00 53.11  ? 193 GLU B N   1 
ATOM   2662  C CA  . GLU B 2 171 ? 129.267 151.091 147.050 1.00 53.11  ? 193 GLU B CA  1 
ATOM   2663  C C   . GLU B 2 171 ? 130.030 152.392 146.847 1.00 53.11  ? 193 GLU B C   1 
ATOM   2664  O O   . GLU B 2 171 ? 130.111 153.216 147.764 1.00 53.11  ? 193 GLU B O   1 
ATOM   2665  C CB  . GLU B 2 171 ? 127.772 151.362 147.231 1.00 53.11  ? 193 GLU B CB  1 
ATOM   2666  C CG  . GLU B 2 171 ? 127.191 152.328 146.217 1.00 53.11  ? 193 GLU B CG  1 
ATOM   2667  C CD  . GLU B 2 171 ? 125.682 152.225 146.116 1.00 53.11  ? 193 GLU B CD  1 
ATOM   2668  O OE1 . GLU B 2 171 ? 125.166 151.090 146.053 1.00 53.11  ? 193 GLU B OE1 1 
ATOM   2669  O OE2 . GLU B 2 171 ? 125.013 153.279 146.100 1.00 53.11  ? 193 GLU B OE2 1 
ATOM   2670  N N   . VAL B 2 172 ? 130.583 152.575 145.649 1.00 49.53  ? 194 VAL B N   1 
ATOM   2671  C CA  . VAL B 2 172 ? 131.399 153.739 145.333 1.00 49.53  ? 194 VAL B CA  1 
ATOM   2672  C C   . VAL B 2 172 ? 130.853 154.415 144.084 1.00 49.53  ? 194 VAL B C   1 
ATOM   2673  O O   . VAL B 2 172 ? 130.226 153.780 143.230 1.00 49.53  ? 194 VAL B O   1 
ATOM   2674  C CB  . VAL B 2 172 ? 132.885 153.365 145.137 1.00 49.53  ? 194 VAL B CB  1 
ATOM   2675  C CG1 . VAL B 2 172 ? 133.466 152.805 146.423 1.00 49.53  ? 194 VAL B CG1 1 
ATOM   2676  C CG2 . VAL B 2 172 ? 133.035 152.365 144.003 1.00 49.53  ? 194 VAL B CG2 1 
ATOM   2677  N N   . TRP B 2 173 ? 131.097 155.720 143.985 1.00 53.28  ? 195 TRP B N   1 
ATOM   2678  C CA  . TRP B 2 173 ? 130.705 156.504 142.822 1.00 53.28  ? 195 TRP B CA  1 
ATOM   2679  C C   . TRP B 2 173 ? 131.484 157.810 142.836 1.00 53.28  ? 195 TRP B C   1 
ATOM   2680  O O   . TRP B 2 173 ? 131.907 158.282 143.894 1.00 53.28  ? 195 TRP B O   1 
ATOM   2681  C CB  . TRP B 2 173 ? 129.196 156.775 142.801 1.00 53.28  ? 195 TRP B CB  1 
ATOM   2682  C CG  . TRP B 2 173 ? 128.732 157.717 143.868 1.00 53.28  ? 195 TRP B CG  1 
ATOM   2683  C CD1 . TRP B 2 173 ? 128.615 159.072 143.771 1.00 53.28  ? 195 TRP B CD1 1 
ATOM   2684  C CD2 . TRP B 2 173 ? 128.315 157.373 145.195 1.00 53.28  ? 195 TRP B CD2 1 
ATOM   2685  N NE1 . TRP B 2 173 ? 128.156 159.594 144.954 1.00 53.28  ? 195 TRP B NE1 1 
ATOM   2686  C CE2 . TRP B 2 173 ? 127.963 158.572 145.845 1.00 53.28  ? 195 TRP B CE2 1 
ATOM   2687  C CE3 . TRP B 2 173 ? 128.207 156.169 145.896 1.00 53.28  ? 195 TRP B CE3 1 
ATOM   2688  C CZ2 . TRP B 2 173 ? 127.510 158.601 147.162 1.00 53.28  ? 195 TRP B CZ2 1 
ATOM   2689  C CZ3 . TRP B 2 173 ? 127.757 156.201 147.203 1.00 53.28  ? 195 TRP B CZ3 1 
ATOM   2690  C CH2 . TRP B 2 173 ? 127.415 157.408 147.822 1.00 53.28  ? 195 TRP B CH2 1 
ATOM   2691  N N   . VAL B 2 174 ? 131.667 158.387 141.651 1.00 54.11  ? 196 VAL B N   1 
ATOM   2692  C CA  . VAL B 2 174 ? 132.442 159.609 141.477 1.00 54.11  ? 196 VAL B CA  1 
ATOM   2693  C C   . VAL B 2 174 ? 131.516 160.713 140.986 1.00 54.11  ? 196 VAL B C   1 
ATOM   2694  O O   . VAL B 2 174 ? 130.618 160.469 140.172 1.00 54.11  ? 196 VAL B O   1 
ATOM   2695  C CB  . VAL B 2 174 ? 133.621 159.395 140.502 1.00 54.11  ? 196 VAL B CB  1 
ATOM   2696  C CG1 . VAL B 2 174 ? 133.129 158.840 139.174 1.00 54.11  ? 196 VAL B CG1 1 
ATOM   2697  C CG2 . VAL B 2 174 ? 134.397 160.687 140.297 1.00 54.11  ? 196 VAL B CG2 1 
ATOM   2698  N N   . GLU B 2 175 ? 131.729 161.925 141.493 1.00 60.75  ? 197 GLU B N   1 
ATOM   2699  C CA  . GLU B 2 175 ? 130.944 163.093 141.119 1.00 60.75  ? 197 GLU B CA  1 
ATOM   2700  C C   . GLU B 2 175 ? 131.844 164.107 140.426 1.00 60.75  ? 197 GLU B C   1 
ATOM   2701  O O   . GLU B 2 175 ? 132.930 164.422 140.925 1.00 60.75  ? 197 GLU B O   1 
ATOM   2702  C CB  . GLU B 2 175 ? 130.283 163.726 142.345 1.00 60.75  ? 197 GLU B CB  1 
ATOM   2703  C CG  . GLU B 2 175 ? 129.748 162.723 143.351 1.00 60.75  ? 197 GLU B CG  1 
ATOM   2704  C CD  . GLU B 2 175 ? 128.951 163.380 144.460 1.00 60.75  ? 197 GLU B CD  1 
ATOM   2705  O OE1 . GLU B 2 175 ? 127.909 163.999 144.159 1.00 60.75  ? 197 GLU B OE1 1 
ATOM   2706  O OE2 . GLU B 2 175 ? 129.367 163.278 145.633 1.00 60.75  ? 197 GLU B OE2 1 
ATOM   2707  N N   . ALA B 2 176 ? 131.391 164.612 139.282 1.00 68.09  ? 198 ALA B N   1 
ATOM   2708  C CA  . ALA B 2 176 ? 132.126 165.609 138.514 1.00 68.09  ? 198 ALA B CA  1 
ATOM   2709  C C   . ALA B 2 176 ? 131.483 166.973 138.728 1.00 68.09  ? 198 ALA B C   1 
ATOM   2710  O O   . ALA B 2 176 ? 130.296 167.156 138.441 1.00 68.09  ? 198 ALA B O   1 
ATOM   2711  C CB  . ALA B 2 176 ? 132.143 165.249 137.029 1.00 68.09  ? 198 ALA B CB  1 
ATOM   2712  N N   . GLU B 2 177 ? 132.266 167.926 139.229 1.00 79.40  ? 199 GLU B N   1 
ATOM   2713  C CA  . GLU B 2 177 ? 131.778 169.267 139.515 1.00 79.40  ? 199 GLU B CA  1 
ATOM   2714  C C   . GLU B 2 177 ? 132.718 170.300 138.914 1.00 79.40  ? 199 GLU B C   1 
ATOM   2715  O O   . GLU B 2 177 ? 133.942 170.171 139.010 1.00 79.40  ? 199 GLU B O   1 
ATOM   2716  C CB  . GLU B 2 177 ? 131.646 169.501 141.025 1.00 79.40  ? 199 GLU B CB  1 
ATOM   2717  C CG  . GLU B 2 177 ? 130.911 170.781 141.391 1.00 79.40  ? 199 GLU B CG  1 
ATOM   2718  C CD  . GLU B 2 177 ? 131.010 171.110 142.868 1.00 79.40  ? 199 GLU B CD  1 
ATOM   2719  O OE1 . GLU B 2 177 ? 132.050 171.660 143.288 1.00 79.40  ? 199 GLU B OE1 1 
ATOM   2720  O OE2 . GLU B 2 177 ? 130.048 170.820 143.610 1.00 79.40  ? 199 GLU B OE2 1 
ATOM   2721  N N   . ASN B 2 178 ? 132.136 171.324 138.296 1.00 80.83  ? 200 ASN B N   1 
ATOM   2722  C CA  . ASN B 2 178 ? 132.889 172.435 137.729 1.00 80.83  ? 200 ASN B CA  1 
ATOM   2723  C C   . ASN B 2 178 ? 132.110 173.717 138.002 1.00 80.83  ? 200 ASN B C   1 
ATOM   2724  O O   . ASN B 2 178 ? 131.185 173.744 138.819 1.00 80.83  ? 200 ASN B O   1 
ATOM   2725  C CB  . ASN B 2 178 ? 133.152 172.213 136.233 1.00 80.83  ? 200 ASN B CB  1 
ATOM   2726  C CG  . ASN B 2 178 ? 131.917 172.434 135.382 1.00 80.83  ? 200 ASN B CG  1 
ATOM   2727  O OD1 . ASN B 2 178 ? 130.800 172.124 135.794 1.00 80.83  ? 200 ASN B OD1 1 
ATOM   2728  N ND2 . ASN B 2 178 ? 132.114 172.974 134.186 1.00 80.83  ? 200 ASN B ND2 1 
ATOM   2729  N N   . ALA B 2 179 ? 132.487 174.791 137.314 1.00 73.53  ? 201 ALA B N   1 
ATOM   2730  C CA  . ALA B 2 179 ? 131.837 176.084 137.484 1.00 73.53  ? 201 ALA B CA  1 
ATOM   2731  C C   . ALA B 2 179 ? 130.516 176.197 136.731 1.00 73.53  ? 201 ALA B C   1 
ATOM   2732  O O   . ALA B 2 179 ? 129.960 177.298 136.656 1.00 73.53  ? 201 ALA B O   1 
ATOM   2733  C CB  . ALA B 2 179 ? 132.780 177.206 137.042 1.00 73.53  ? 201 ALA B CB  1 
ATOM   2734  N N   . LEU B 2 180 ? 129.998 175.100 136.174 1.00 78.36  ? 202 LEU B N   1 
ATOM   2735  C CA  . LEU B 2 180 ? 128.751 175.143 135.423 1.00 78.36  ? 202 LEU B CA  1 
ATOM   2736  C C   . LEU B 2 180 ? 127.770 174.028 135.756 1.00 78.36  ? 202 LEU B C   1 
ATOM   2737  O O   . LEU B 2 180 ? 126.646 174.058 135.242 1.00 78.36  ? 202 LEU B O   1 
ATOM   2738  C CB  . LEU B 2 180 ? 129.032 175.114 133.913 1.00 78.36  ? 202 LEU B CB  1 
ATOM   2739  C CG  . LEU B 2 180 ? 129.235 176.481 133.260 1.00 78.36  ? 202 LEU B CG  1 
ATOM   2740  C CD1 . LEU B 2 180 ? 129.424 176.335 131.762 1.00 78.36  ? 202 LEU B CD1 1 
ATOM   2741  C CD2 . LEU B 2 180 ? 128.060 177.395 133.568 1.00 78.36  ? 202 LEU B CD2 1 
ATOM   2742  N N   . GLY B 2 181 ? 128.142 173.057 136.579 1.00 69.68  ? 203 GLY B N   1 
ATOM   2743  C CA  . GLY B 2 181 ? 127.215 172.002 136.937 1.00 69.68  ? 203 GLY B CA  1 
ATOM   2744  C C   . GLY B 2 181 ? 127.913 170.901 137.698 1.00 69.68  ? 203 GLY B C   1 
ATOM   2745  O O   . GLY B 2 181 ? 129.143 170.792 137.708 1.00 69.68  ? 203 GLY B O   1 
ATOM   2746  N N   . LYS B 2 182 ? 127.094 170.075 138.344 1.00 68.90  ? 204 LYS B N   1 
ATOM   2747  C CA  . LYS B 2 182 ? 127.567 168.929 139.108 1.00 68.90  ? 204 LYS B CA  1 
ATOM   2748  C C   . LYS B 2 182 ? 126.788 167.695 138.681 1.00 68.90  ? 204 LYS B C   1 
ATOM   2749  O O   . LYS B 2 182 ? 125.555 167.685 138.740 1.00 68.90  ? 204 LYS B O   1 
ATOM   2750  C CB  . LYS B 2 182 ? 127.411 169.162 140.614 1.00 68.90  ? 204 LYS B CB  1 
ATOM   2751  C CG  . LYS B 2 182 ? 127.936 168.024 141.472 1.00 68.90  ? 204 LYS B CG  1 
ATOM   2752  C CD  . LYS B 2 182 ? 127.790 168.333 142.952 1.00 68.90  ? 204 LYS B CD  1 
ATOM   2753  C CE  . LYS B 2 182 ? 128.450 167.263 143.805 1.00 68.90  ? 204 LYS B CE  1 
ATOM   2754  N NZ  . LYS B 2 182 ? 128.285 167.531 145.260 1.00 68.90  ? 204 LYS B NZ  1 
ATOM   2755  N N   . VAL B 2 183 ? 127.508 166.660 138.255 1.00 60.25  ? 205 VAL B N   1 
ATOM   2756  C CA  . VAL B 2 183 ? 126.903 165.412 137.807 1.00 60.25  ? 205 VAL B CA  1 
ATOM   2757  C C   . VAL B 2 183 ? 127.709 164.253 138.376 1.00 60.25  ? 205 VAL B C   1 
ATOM   2758  O O   . VAL B 2 183 ? 128.944 164.297 138.411 1.00 60.25  ? 205 VAL B O   1 
ATOM   2759  C CB  . VAL B 2 183 ? 126.824 165.344 136.266 1.00 60.25  ? 205 VAL B CB  1 
ATOM   2760  C CG1 . VAL B 2 183 ? 128.199 165.544 135.645 1.00 60.25  ? 205 VAL B CG1 1 
ATOM   2761  C CG2 . VAL B 2 183 ? 126.211 164.028 135.814 1.00 60.25  ? 205 VAL B CG2 1 
ATOM   2762  N N   . SER B 2 184 ? 127.008 163.221 138.838 1.00 56.41  ? 206 SER B N   1 
ATOM   2763  C CA  . SER B 2 184 ? 127.627 162.044 139.428 1.00 56.41  ? 206 SER B CA  1 
ATOM   2764  C C   . SER B 2 184 ? 127.353 160.827 138.557 1.00 56.41  ? 206 SER B C   1 
ATOM   2765  O O   . SER B 2 184 ? 126.268 160.695 137.982 1.00 56.41  ? 206 SER B O   1 
ATOM   2766  C CB  . SER B 2 184 ? 127.107 161.798 140.848 1.00 56.41  ? 206 SER B CB  1 
ATOM   2767  O OG  . SER B 2 184 ? 125.696 161.668 140.857 1.00 56.41  ? 206 SER B OG  1 
ATOM   2768  N N   . SER B 2 185 ? 128.340 159.940 138.464 1.00 56.97  ? 207 SER B N   1 
ATOM   2769  C CA  . SER B 2 185 ? 128.217 158.739 137.654 1.00 56.97  ? 207 SER B CA  1 
ATOM   2770  C C   . SER B 2 185 ? 127.371 157.694 138.378 1.00 56.97  ? 207 SER B C   1 
ATOM   2771  O O   . SER B 2 185 ? 126.836 157.926 139.465 1.00 56.97  ? 207 SER B O   1 
ATOM   2772  C CB  . SER B 2 185 ? 129.597 158.182 137.319 1.00 56.97  ? 207 SER B CB  1 
ATOM   2773  O OG  . SER B 2 185 ? 130.196 157.595 138.461 1.00 56.97  ? 207 SER B OG  1 
ATOM   2774  N N   . GLU B 2 186 ? 127.252 156.521 137.765 1.00 57.01  ? 208 GLU B N   1 
ATOM   2775  C CA  . GLU B 2 186 ? 126.508 155.427 138.365 1.00 57.01  ? 208 GLU B CA  1 
ATOM   2776  C C   . GLU B 2 186 ? 127.348 154.730 139.429 1.00 57.01  ? 208 GLU B C   1 
ATOM   2777  O O   . GLU B 2 186 ? 128.578 154.677 139.345 1.00 57.01  ? 208 GLU B O   1 
ATOM   2778  C CB  . GLU B 2 186 ? 126.075 154.422 137.298 1.00 57.01  ? 208 GLU B CB  1 
ATOM   2779  C CG  . GLU B 2 186 ? 125.268 155.028 136.160 1.00 57.01  ? 208 GLU B CG  1 
ATOM   2780  C CD  . GLU B 2 186 ? 123.832 155.323 136.550 1.00 57.01  ? 208 GLU B CD  1 
ATOM   2781  O OE1 . GLU B 2 186 ? 123.603 156.282 137.316 1.00 57.01  ? 208 GLU B OE1 1 
ATOM   2782  O OE2 . GLU B 2 186 ? 122.930 154.594 136.088 1.00 57.01  ? 208 GLU B OE2 1 
ATOM   2783  N N   . SER B 2 187 ? 126.669 154.195 140.437 1.00 50.77  ? 209 SER B N   1 
ATOM   2784  C CA  . SER B 2 187 ? 127.332 153.516 141.539 1.00 50.77  ? 209 SER B CA  1 
ATOM   2785  C C   . SER B 2 187 ? 127.418 152.019 141.274 1.00 50.77  ? 209 SER B C   1 
ATOM   2786  O O   . SER B 2 187 ? 126.537 151.427 140.645 1.00 50.77  ? 209 SER B O   1 
ATOM   2787  C CB  . SER B 2 187 ? 126.590 153.767 142.852 1.00 50.77  ? 209 SER B CB  1 
ATOM   2788  O OG  . SER B 2 187 ? 125.512 152.861 143.005 1.00 50.77  ? 209 SER B OG  1 
ATOM   2789  N N   . ILE B 2 188 ? 128.495 151.410 141.764 1.00 49.53  ? 210 ILE B N   1 
ATOM   2790  C CA  . ILE B 2 188 ? 128.723 149.977 141.636 1.00 49.53  ? 210 ILE B CA  1 
ATOM   2791  C C   . ILE B 2 188 ? 128.816 149.371 143.028 1.00 49.53  ? 210 ILE B C   1 
ATOM   2792  O O   . ILE B 2 188 ? 129.386 149.976 143.943 1.00 49.53  ? 210 ILE B O   1 
ATOM   2793  C CB  . ILE B 2 188 ? 129.995 149.667 140.820 1.00 49.53  ? 210 ILE B CB  1 
ATOM   2794  C CG1 . ILE B 2 188 ? 131.192 150.440 141.376 1.00 49.53  ? 210 ILE B CG1 1 
ATOM   2795  C CG2 . ILE B 2 188 ? 129.779 149.995 139.352 1.00 49.53  ? 210 ILE B CG2 1 
ATOM   2796  C CD1 . ILE B 2 188 ? 132.496 150.128 140.679 1.00 49.53  ? 210 ILE B CD1 1 
ATOM   2797  N N   . ASN B 2 189 ? 128.249 148.178 143.187 1.00 48.80  ? 211 ASN B N   1 
ATOM   2798  C CA  . ASN B 2 189 ? 128.273 147.447 144.447 1.00 48.80  ? 211 ASN B CA  1 
ATOM   2799  C C   . ASN B 2 189 ? 129.072 146.168 144.245 1.00 48.80  ? 211 ASN B C   1 
ATOM   2800  O O   . ASN B 2 189 ? 128.659 145.291 143.479 1.00 48.80  ? 211 ASN B O   1 
ATOM   2801  C CB  . ASN B 2 189 ? 126.855 147.131 144.927 1.00 48.80  ? 211 ASN B CB  1 
ATOM   2802  C CG  . ASN B 2 189 ? 126.791 146.863 146.416 1.00 48.80  ? 211 ASN B CG  1 
ATOM   2803  O OD1 . ASN B 2 189 ? 127.793 146.517 147.040 1.00 48.80  ? 211 ASN B OD1 1 
ATOM   2804  N ND2 . ASN B 2 189 ? 125.607 147.023 146.995 1.00 48.80  ? 211 ASN B ND2 1 
ATOM   2805  N N   . PHE B 2 190 ? 130.208 146.064 144.930 1.00 40.62  ? 212 PHE B N   1 
ATOM   2806  C CA  . PHE B 2 190 ? 131.113 144.938 144.754 1.00 40.62  ? 212 PHE B CA  1 
ATOM   2807  C C   . PHE B 2 190 ? 131.718 144.555 146.096 1.00 40.62  ? 212 PHE B C   1 
ATOM   2808  O O   . PHE B 2 190 ? 131.548 145.247 147.104 1.00 40.62  ? 212 PHE B O   1 
ATOM   2809  C CB  . PHE B 2 190 ? 132.220 145.263 143.743 1.00 40.62  ? 212 PHE B CB  1 
ATOM   2810  C CG  . PHE B 2 190 ? 133.202 146.289 144.230 1.00 40.62  ? 212 PHE B CG  1 
ATOM   2811  C CD1 . PHE B 2 190 ? 132.890 147.636 144.198 1.00 40.62  ? 212 PHE B CD1 1 
ATOM   2812  C CD2 . PHE B 2 190 ? 134.441 145.906 144.716 1.00 40.62  ? 212 PHE B CD2 1 
ATOM   2813  C CE1 . PHE B 2 190 ? 133.791 148.582 144.644 1.00 40.62  ? 212 PHE B CE1 1 
ATOM   2814  C CE2 . PHE B 2 190 ? 135.346 146.847 145.164 1.00 40.62  ? 212 PHE B CE2 1 
ATOM   2815  C CZ  . PHE B 2 190 ? 135.020 148.186 145.128 1.00 40.62  ? 212 PHE B CZ  1 
ATOM   2816  N N   . ASP B 2 191 ? 132.435 143.432 146.096 1.00 40.99  ? 213 ASP B N   1 
ATOM   2817  C CA  . ASP B 2 191 ? 133.143 142.911 147.258 1.00 40.99  ? 213 ASP B CA  1 
ATOM   2818  C C   . ASP B 2 191 ? 134.635 143.141 147.093 1.00 40.99  ? 213 ASP B C   1 
ATOM   2819  O O   . ASP B 2 191 ? 135.199 142.760 146.057 1.00 40.99  ? 213 ASP B O   1 
ATOM   2820  C CB  . ASP B 2 191 ? 132.862 141.421 147.427 1.00 40.99  ? 213 ASP B CB  1 
ATOM   2821  C CG  . ASP B 2 191 ? 133.116 140.932 148.840 1.00 40.99  ? 213 ASP B CG  1 
ATOM   2822  O OD1 . ASP B 2 191 ? 134.126 141.341 149.447 1.00 40.99  ? 213 ASP B OD1 1 
ATOM   2823  O OD2 . ASP B 2 191 ? 132.302 140.130 149.343 1.00 40.99  ? 213 ASP B OD2 1 
ATOM   2824  N N   . PRO B 2 192 ? 135.307 143.760 148.067 1.00 39.59  ? 214 PRO B N   1 
ATOM   2825  C CA  . PRO B 2 192 ? 136.755 143.988 147.928 1.00 39.59  ? 214 PRO B CA  1 
ATOM   2826  C C   . PRO B 2 192 ? 137.571 142.713 147.805 1.00 39.59  ? 214 PRO B C   1 
ATOM   2827  O O   . PRO B 2 192 ? 138.730 142.780 147.380 1.00 39.59  ? 214 PRO B O   1 
ATOM   2828  C CB  . PRO B 2 192 ? 137.113 144.758 149.206 1.00 39.59  ? 214 PRO B CB  1 
ATOM   2829  C CG  . PRO B 2 192 ? 135.835 145.389 149.639 1.00 39.59  ? 214 PRO B CG  1 
ATOM   2830  C CD  . PRO B 2 192 ? 134.755 144.421 149.260 1.00 39.59  ? 214 PRO B CD  1 
ATOM   2831  N N   . VAL B 2 193 ? 137.011 141.556 148.163 1.00 42.01  ? 215 VAL B N   1 
ATOM   2832  C CA  . VAL B 2 193 ? 137.750 140.305 148.031 1.00 42.01  ? 215 VAL B CA  1 
ATOM   2833  C C   . VAL B 2 193 ? 137.738 139.785 146.598 1.00 42.01  ? 215 VAL B C   1 
ATOM   2834  O O   . VAL B 2 193 ? 138.604 138.981 146.231 1.00 42.01  ? 215 VAL B O   1 
ATOM   2835  C CB  . VAL B 2 193 ? 137.190 139.245 148.997 1.00 42.01  ? 215 VAL B CB  1 
ATOM   2836  C CG1 . VAL B 2 193 ? 135.860 138.702 148.493 1.00 42.01  ? 215 VAL B CG1 1 
ATOM   2837  C CG2 . VAL B 2 193 ? 138.195 138.123 149.212 1.00 42.01  ? 215 VAL B CG2 1 
ATOM   2838  N N   . ASP B 2 194 ? 136.792 140.228 145.773 1.00 46.92  ? 216 ASP B N   1 
ATOM   2839  C CA  . ASP B 2 194 ? 136.702 139.795 144.385 1.00 46.92  ? 216 ASP B CA  1 
ATOM   2840  C C   . ASP B 2 194 ? 137.483 140.688 143.430 1.00 46.92  ? 216 ASP B C   1 
ATOM   2841  O O   . ASP B 2 194 ? 137.408 140.482 142.214 1.00 46.92  ? 216 ASP B O   1 
ATOM   2842  C CB  . ASP B 2 194 ? 135.236 139.735 143.945 1.00 46.92  ? 216 ASP B CB  1 
ATOM   2843  C CG  . ASP B 2 194 ? 134.487 138.581 144.577 1.00 46.92  ? 216 ASP B CG  1 
ATOM   2844  O OD1 . ASP B 2 194 ? 135.120 137.788 145.304 1.00 46.92  ? 216 ASP B OD1 1 
ATOM   2845  O OD2 . ASP B 2 194 ? 133.265 138.467 144.347 1.00 46.92  ? 216 ASP B OD2 1 
ATOM   2846  N N   . LYS B 2 195 ? 138.222 141.671 143.944 1.00 42.66  ? 217 LYS B N   1 
ATOM   2847  C CA  . LYS B 2 195 ? 139.034 142.557 143.118 1.00 42.66  ? 217 LYS B CA  1 
ATOM   2848  C C   . LYS B 2 195 ? 140.502 142.528 143.528 1.00 42.66  ? 217 LYS B C   1 
ATOM   2849  O O   . LYS B 2 195 ? 141.243 143.472 143.240 1.00 42.66  ? 217 LYS B O   1 
ATOM   2850  C CB  . LYS B 2 195 ? 138.497 143.988 143.178 1.00 42.66  ? 217 LYS B CB  1 
ATOM   2851  C CG  . LYS B 2 195 ? 137.009 144.110 142.901 1.00 42.66  ? 217 LYS B CG  1 
ATOM   2852  C CD  . LYS B 2 195 ? 136.663 143.631 141.503 1.00 42.66  ? 217 LYS B CD  1 
ATOM   2853  C CE  . LYS B 2 195 ? 135.182 143.808 141.213 1.00 42.66  ? 217 LYS B CE  1 
ATOM   2854  N NZ  . LYS B 2 195 ? 134.822 143.337 139.848 1.00 42.66  ? 217 LYS B NZ  1 
ATOM   2855  N N   . VAL B 2 196 ? 140.935 141.464 144.196 1.00 45.48  ? 218 VAL B N   1 
ATOM   2856  C CA  . VAL B 2 196 ? 142.302 141.377 144.696 1.00 45.48  ? 218 VAL B CA  1 
ATOM   2857  C C   . VAL B 2 196 ? 143.217 140.896 143.579 1.00 45.48  ? 218 VAL B C   1 
ATOM   2858  O O   . VAL B 2 196 ? 142.929 139.898 142.907 1.00 45.48  ? 218 VAL B O   1 
ATOM   2859  C CB  . VAL B 2 196 ? 142.378 140.444 145.914 1.00 45.48  ? 218 VAL B CB  1 
ATOM   2860  C CG1 . VAL B 2 196 ? 143.804 140.363 146.433 1.00 45.48  ? 218 VAL B CG1 1 
ATOM   2861  C CG2 . VAL B 2 196 ? 141.434 140.920 147.005 1.00 45.48  ? 218 VAL B CG2 1 
ATOM   2862  N N   . LYS B 2 197 ? 144.326 141.609 143.375 1.00 52.59  ? 219 LYS B N   1 
ATOM   2863  C CA  . LYS B 2 197 ? 145.356 141.194 142.435 1.00 52.59  ? 219 LYS B CA  1 
ATOM   2864  C C   . LYS B 2 197 ? 146.539 140.656 143.227 1.00 52.59  ? 219 LYS B C   1 
ATOM   2865  O O   . LYS B 2 197 ? 147.333 141.446 143.760 1.00 52.59  ? 219 LYS B O   1 
ATOM   2866  C CB  . LYS B 2 197 ? 145.787 142.362 141.545 1.00 52.59  ? 219 LYS B CB  1 
ATOM   2867  C CG  . LYS B 2 197 ? 146.814 141.986 140.491 1.00 52.59  ? 219 LYS B CG  1 
ATOM   2868  C CD  . LYS B 2 197 ? 147.125 143.158 139.577 1.00 52.59  ? 219 LYS B CD  1 
ATOM   2869  C CE  . LYS B 2 197 ? 148.108 142.760 138.490 1.00 52.59  ? 219 LYS B CE  1 
ATOM   2870  N NZ  . LYS B 2 197 ? 148.384 143.880 137.550 1.00 52.59  ? 219 LYS B NZ  1 
ATOM   2871  N N   . PRO B 2 198 ? 146.704 139.341 143.341 1.00 54.05  ? 220 PRO B N   1 
ATOM   2872  C CA  . PRO B 2 198 ? 147.769 138.799 144.190 1.00 54.05  ? 220 PRO B CA  1 
ATOM   2873  C C   . PRO B 2 198 ? 149.149 139.071 143.613 1.00 54.05  ? 220 PRO B C   1 
ATOM   2874  O O   . PRO B 2 198 ? 149.315 139.414 142.441 1.00 54.05  ? 220 PRO B O   1 
ATOM   2875  C CB  . PRO B 2 198 ? 147.473 137.294 144.224 1.00 54.05  ? 220 PRO B CB  1 
ATOM   2876  C CG  . PRO B 2 198 ? 146.076 137.145 143.687 1.00 54.05  ? 220 PRO B CG  1 
ATOM   2877  C CD  . PRO B 2 198 ? 145.887 138.279 142.736 1.00 54.05  ? 220 PRO B CD  1 
ATOM   2878  N N   . THR B 2 199 ? 150.152 138.916 144.472 1.00 59.74  ? 221 THR B N   1 
ATOM   2879  C CA  . THR B 2 199 ? 151.536 139.041 144.051 1.00 59.74  ? 221 THR B CA  1 
ATOM   2880  C C   . THR B 2 199 ? 152.014 137.737 143.413 1.00 59.74  ? 221 THR B C   1 
ATOM   2881  O O   . THR B 2 199 ? 151.554 136.653 143.783 1.00 59.74  ? 221 THR B O   1 
ATOM   2882  C CB  . THR B 2 199 ? 152.428 139.390 145.239 1.00 59.74  ? 221 THR B CB  1 
ATOM   2883  O OG1 . THR B 2 199 ? 152.184 138.468 146.308 1.00 59.74  ? 221 THR B OG1 1 
ATOM   2884  C CG2 . THR B 2 199 ? 152.142 140.804 145.720 1.00 59.74  ? 221 THR B CG2 1 
ATOM   2885  N N   . PRO B 2 200 ? 152.927 137.815 142.449 1.00 60.07  ? 222 PRO B N   1 
ATOM   2886  C CA  . PRO B 2 200 ? 153.422 136.599 141.796 1.00 60.07  ? 222 PRO B CA  1 
ATOM   2887  C C   . PRO B 2 200 ? 154.176 135.722 142.778 1.00 60.07  ? 222 PRO B C   1 
ATOM   2888  O O   . PRO B 2 200 ? 154.926 136.228 143.626 1.00 60.07  ? 222 PRO B O   1 
ATOM   2889  C CB  . PRO B 2 200 ? 154.354 137.139 140.700 1.00 60.07  ? 222 PRO B CB  1 
ATOM   2890  C CG  . PRO B 2 200 ? 154.734 138.504 141.162 1.00 60.07  ? 222 PRO B CG  1 
ATOM   2891  C CD  . PRO B 2 200 ? 153.530 139.031 141.879 1.00 60.07  ? 222 PRO B CD  1 
ATOM   2892  N N   . PRO B 2 201 ? 153.991 134.404 142.705 1.00 64.61  ? 223 PRO B N   1 
ATOM   2893  C CA  . PRO B 2 201 ? 154.704 133.509 143.623 1.00 64.61  ? 223 PRO B CA  1 
ATOM   2894  C C   . PRO B 2 201 ? 156.209 133.583 143.415 1.00 64.61  ? 223 PRO B C   1 
ATOM   2895  O O   . PRO B 2 201 ? 156.697 133.818 142.307 1.00 64.61  ? 223 PRO B O   1 
ATOM   2896  C CB  . PRO B 2 201 ? 154.158 132.121 143.265 1.00 64.61  ? 223 PRO B CB  1 
ATOM   2897  C CG  . PRO B 2 201 ? 152.862 132.385 142.564 1.00 64.61  ? 223 PRO B CG  1 
ATOM   2898  C CD  . PRO B 2 201 ? 153.059 133.674 141.832 1.00 64.61  ? 223 PRO B CD  1 
ATOM   2899  N N   . TYR B 2 202 ? 156.945 133.377 144.500 1.00 70.28  ? 224 TYR B N   1 
ATOM   2900  C CA  . TYR B 2 202 ? 158.398 133.459 144.500 1.00 70.28  ? 224 TYR B CA  1 
ATOM   2901  C C   . TYR B 2 202 ? 158.990 132.139 144.985 1.00 70.28  ? 224 TYR B C   1 
ATOM   2902  O O   . TYR B 2 202 ? 158.273 131.215 145.378 1.00 70.28  ? 224 TYR B O   1 
ATOM   2903  C CB  . TYR B 2 202 ? 158.877 134.627 145.367 1.00 70.28  ? 224 TYR B CB  1 
ATOM   2904  C CG  . TYR B 2 202 ? 158.186 134.725 146.709 1.00 70.28  ? 224 TYR B CG  1 
ATOM   2905  C CD1 . TYR B 2 202 ? 157.059 135.520 146.875 1.00 70.28  ? 224 TYR B CD1 1 
ATOM   2906  C CD2 . TYR B 2 202 ? 158.661 134.025 147.809 1.00 70.28  ? 224 TYR B CD2 1 
ATOM   2907  C CE1 . TYR B 2 202 ? 156.425 135.613 148.099 1.00 70.28  ? 224 TYR B CE1 1 
ATOM   2908  C CE2 . TYR B 2 202 ? 158.034 134.112 149.037 1.00 70.28  ? 224 TYR B CE2 1 
ATOM   2909  C CZ  . TYR B 2 202 ? 156.917 134.907 149.176 1.00 70.28  ? 224 TYR B CZ  1 
ATOM   2910  O OH  . TYR B 2 202 ? 156.290 134.996 150.397 1.00 70.28  ? 224 TYR B OH  1 
ATOM   2911  N N   . ASN B 2 203 ? 160.323 132.066 144.947 1.00 74.21  ? 225 ASN B N   1 
ATOM   2912  C CA  . ASN B 2 203 ? 161.071 130.879 145.363 1.00 74.21  ? 225 ASN B CA  1 
ATOM   2913  C C   . ASN B 2 203 ? 160.640 129.644 144.575 1.00 74.21  ? 225 ASN B C   1 
ATOM   2914  O O   . ASN B 2 203 ? 160.483 128.553 145.126 1.00 74.21  ? 225 ASN B O   1 
ATOM   2915  C CB  . ASN B 2 203 ? 160.942 130.641 146.870 1.00 74.21  ? 225 ASN B CB  1 
ATOM   2916  C CG  . ASN B 2 203 ? 161.713 131.659 147.684 1.00 74.21  ? 225 ASN B CG  1 
ATOM   2917  O OD1 . ASN B 2 203 ? 161.774 132.835 147.327 1.00 74.21  ? 225 ASN B OD1 1 
ATOM   2918  N ND2 . ASN B 2 203 ? 162.309 131.213 148.782 1.00 74.21  ? 225 ASN B ND2 1 
ATOM   2919  N N   . LEU B 2 204 ? 160.449 129.821 143.270 1.00 66.42  ? 226 LEU B N   1 
ATOM   2920  C CA  . LEU B 2 204 ? 160.092 128.708 142.400 1.00 66.42  ? 226 LEU B CA  1 
ATOM   2921  C C   . LEU B 2 204 ? 161.309 127.818 142.182 1.00 66.42  ? 226 LEU B C   1 
ATOM   2922  O O   . LEU B 2 204 ? 162.349 128.282 141.703 1.00 66.42  ? 226 LEU B O   1 
ATOM   2923  C CB  . LEU B 2 204 ? 159.560 129.232 141.068 1.00 66.42  ? 226 LEU B CB  1 
ATOM   2924  C CG  . LEU B 2 204 ? 159.177 128.188 140.018 1.00 66.42  ? 226 LEU B CG  1 
ATOM   2925  C CD1 . LEU B 2 204 ? 158.030 127.323 140.513 1.00 66.42  ? 226 LEU B CD1 1 
ATOM   2926  C CD2 . LEU B 2 204 ? 158.814 128.861 138.706 1.00 66.42  ? 226 LEU B CD2 1 
ATOM   2927  N N   . SER B 2 205 ? 161.183 126.542 142.536 1.00 58.00  ? 227 SER B N   1 
ATOM   2928  C CA  . SER B 2 205 ? 162.272 125.583 142.422 1.00 58.00  ? 227 SER B CA  1 
ATOM   2929  C C   . SER B 2 205 ? 161.831 124.395 141.580 1.00 58.00  ? 227 SER B C   1 
ATOM   2930  O O   . SER B 2 205 ? 160.716 123.889 141.738 1.00 58.00  ? 227 SER B O   1 
ATOM   2931  C CB  . SER B 2 205 ? 162.730 125.102 143.802 1.00 58.00  ? 227 SER B CB  1 
ATOM   2932  O OG  . SER B 2 205 ? 161.914 124.040 144.266 1.00 58.00  ? 227 SER B OG  1 
ATOM   2933  N N   . VAL B 2 206 ? 162.712 123.955 140.687 1.00 60.14  ? 228 VAL B N   1 
ATOM   2934  C CA  . VAL B 2 206 ? 162.461 122.816 139.812 1.00 60.14  ? 228 VAL B CA  1 
ATOM   2935  C C   . VAL B 2 206 ? 163.376 121.681 140.248 1.00 60.14  ? 228 VAL B C   1 
ATOM   2936  O O   . VAL B 2 206 ? 164.603 121.840 140.279 1.00 60.14  ? 228 VAL B O   1 
ATOM   2937  C CB  . VAL B 2 206 ? 162.687 123.172 138.335 1.00 60.14  ? 228 VAL B CB  1 
ATOM   2938  C CG1 . VAL B 2 206 ? 162.399 121.969 137.450 1.00 60.14  ? 228 VAL B CG1 1 
ATOM   2939  C CG2 . VAL B 2 206 ? 161.820 124.355 137.938 1.00 60.14  ? 228 VAL B CG2 1 
ATOM   2940  N N   . THR B 2 207 ? 162.783 120.539 140.583 1.00 67.96  ? 229 THR B N   1 
ATOM   2941  C CA  . THR B 2 207 ? 163.519 119.371 141.043 1.00 67.96  ? 229 THR B CA  1 
ATOM   2942  C C   . THR B 2 207 ? 163.247 118.194 140.118 1.00 67.96  ? 229 THR B C   1 
ATOM   2943  O O   . THR B 2 207 ? 162.112 117.987 139.678 1.00 67.96  ? 229 THR B O   1 
ATOM   2944  C CB  . THR B 2 207 ? 163.134 119.000 142.480 1.00 67.96  ? 229 THR B CB  1 
ATOM   2945  O OG1 . THR B 2 207 ? 161.735 118.695 142.538 1.00 67.96  ? 229 THR B OG1 1 
ATOM   2946  C CG2 . THR B 2 207 ? 163.437 120.150 143.427 1.00 67.96  ? 229 THR B CG2 1 
ATOM   2947  N N   . ASN B 2 208 ? 164.293 117.425 139.828 1.00 70.53  ? 230 ASN B N   1 
ATOM   2948  C CA  . ASN B 2 208 ? 164.173 116.253 138.979 1.00 70.53  ? 230 ASN B CA  1 
ATOM   2949  C C   . ASN B 2 208 ? 163.920 115.010 139.831 1.00 70.53  ? 230 ASN B C   1 
ATOM   2950  O O   . ASN B 2 208 ? 163.810 115.074 141.057 1.00 70.53  ? 230 ASN B O   1 
ATOM   2951  C CB  . ASN B 2 208 ? 165.425 116.087 138.120 1.00 70.53  ? 230 ASN B CB  1 
ATOM   2952  C CG  . ASN B 2 208 ? 166.705 116.265 138.913 1.00 70.53  ? 230 ASN B CG  1 
ATOM   2953  O OD1 . ASN B 2 208 ? 166.688 116.292 140.143 1.00 70.53  ? 230 ASN B OD1 1 
ATOM   2954  N ND2 . ASN B 2 208 ? 167.824 116.387 138.210 1.00 70.53  ? 230 ASN B ND2 1 
ATOM   2955  N N   . SER B 2 209 ? 163.823 113.860 139.169 1.00 80.08  ? 231 SER B N   1 
ATOM   2956  C CA  . SER B 2 209 ? 163.599 112.585 139.837 1.00 80.08  ? 231 SER B CA  1 
ATOM   2957  C C   . SER B 2 209 ? 164.562 111.553 139.274 1.00 80.08  ? 231 SER B C   1 
ATOM   2958  O O   . SER B 2 209 ? 164.684 111.414 138.053 1.00 80.08  ? 231 SER B O   1 
ATOM   2959  C CB  . SER B 2 209 ? 162.154 112.111 139.664 1.00 80.08  ? 231 SER B CB  1 
ATOM   2960  O OG  . SER B 2 209 ? 162.053 110.711 139.859 1.00 80.08  ? 231 SER B OG  1 
ATOM   2961  N N   . GLU B 2 210 ? 165.241 110.829 140.166 1.00 89.16  ? 232 GLU B N   1 
ATOM   2962  C CA  . GLU B 2 210 ? 166.200 109.822 139.723 1.00 89.16  ? 232 GLU B CA  1 
ATOM   2963  C C   . GLU B 2 210 ? 165.506 108.616 139.103 1.00 89.16  ? 232 GLU B C   1 
ATOM   2964  O O   . GLU B 2 210 ? 166.033 108.018 138.159 1.00 89.16  ? 232 GLU B O   1 
ATOM   2965  C CB  . GLU B 2 210 ? 167.080 109.386 140.895 1.00 89.16  ? 232 GLU B CB  1 
ATOM   2966  C CG  . GLU B 2 210 ? 168.228 108.466 140.509 1.00 89.16  ? 232 GLU B CG  1 
ATOM   2967  C CD  . GLU B 2 210 ? 167.877 106.999 140.659 1.00 89.16  ? 232 GLU B CD  1 
ATOM   2968  O OE1 . GLU B 2 210 ? 166.838 106.696 141.282 1.00 89.16  ? 232 GLU B OE1 1 
ATOM   2969  O OE2 . GLU B 2 210 ? 168.639 106.148 140.153 1.00 89.16  ? 232 GLU B OE2 1 
ATOM   2970  N N   . GLU B 2 211 ? 164.330 108.246 139.613 1.00 87.02  ? 233 GLU B N   1 
ATOM   2971  C CA  . GLU B 2 211 ? 163.633 107.074 139.097 1.00 87.02  ? 233 GLU B CA  1 
ATOM   2972  C C   . GLU B 2 211 ? 162.960 107.369 137.761 1.00 87.02  ? 233 GLU B C   1 
ATOM   2973  O O   . GLU B 2 211 ? 163.094 106.596 136.806 1.00 87.02  ? 233 GLU B O   1 
ATOM   2974  C CB  . GLU B 2 211 ? 162.606 106.582 140.118 1.00 87.02  ? 233 GLU B CB  1 
ATOM   2975  C CG  . GLU B 2 211 ? 161.874 105.319 139.701 1.00 87.02  ? 233 GLU B CG  1 
ATOM   2976  C CD  . GLU B 2 211 ? 162.783 104.107 139.649 1.00 87.02  ? 233 GLU B CD  1 
ATOM   2977  O OE1 . GLU B 2 211 ? 163.777 104.074 140.406 1.00 87.02  ? 233 GLU B OE1 1 
ATOM   2978  O OE2 . GLU B 2 211 ? 162.506 103.188 138.851 1.00 87.02  ? 233 GLU B OE2 1 
ATOM   2979  N N   . LEU B 2 212 ? 162.234 108.481 137.676 1.00 83.70  ? 234 LEU B N   1 
ATOM   2980  C CA  . LEU B 2 212 ? 161.518 108.873 136.467 1.00 83.70  ? 234 LEU B CA  1 
ATOM   2981  C C   . LEU B 2 212 ? 162.212 110.091 135.871 1.00 83.70  ? 234 LEU B C   1 
ATOM   2982  O O   . LEU B 2 212 ? 162.123 111.195 136.419 1.00 83.70  ? 234 LEU B O   1 
ATOM   2983  C CB  . LEU B 2 212 ? 160.051 109.167 136.771 1.00 83.70  ? 234 LEU B CB  1 
ATOM   2984  C CG  . LEU B 2 212 ? 159.199 107.973 137.203 1.00 83.70  ? 234 LEU B CG  1 
ATOM   2985  C CD1 . LEU B 2 212 ? 157.778 108.414 137.518 1.00 83.70  ? 234 LEU B CD1 1 
ATOM   2986  C CD2 . LEU B 2 212 ? 159.204 106.895 136.130 1.00 83.70  ? 234 LEU B CD2 1 
ATOM   2987  N N   . SER B 2 213 ? 162.902 109.888 134.750 1.00 78.99  ? 235 SER B N   1 
ATOM   2988  C CA  . SER B 2 213 ? 163.617 110.967 134.083 1.00 78.99  ? 235 SER B CA  1 
ATOM   2989  C C   . SER B 2 213 ? 162.711 111.851 133.237 1.00 78.99  ? 235 SER B C   1 
ATOM   2990  O O   . SER B 2 213 ? 163.134 112.943 132.842 1.00 78.99  ? 235 SER B O   1 
ATOM   2991  C CB  . SER B 2 213 ? 164.728 110.391 133.204 1.00 78.99  ? 235 SER B CB  1 
ATOM   2992  O OG  . SER B 2 213 ? 164.259 109.278 132.464 1.00 78.99  ? 235 SER B OG  1 
ATOM   2993  N N   . SER B 2 214 ? 161.485 111.414 132.951 1.00 77.10  ? 236 SER B N   1 
ATOM   2994  C CA  . SER B 2 214 ? 160.570 112.153 132.093 1.00 77.10  ? 236 SER B CA  1 
ATOM   2995  C C   . SER B 2 214 ? 159.622 113.056 132.875 1.00 77.10  ? 236 SER B C   1 
ATOM   2996  O O   . SER B 2 214 ? 158.619 113.515 132.317 1.00 77.10  ? 236 SER B O   1 
ATOM   2997  C CB  . SER B 2 214 ? 159.767 111.182 131.224 1.00 77.10  ? 236 SER B CB  1 
ATOM   2998  O OG  . SER B 2 214 ? 160.603 110.181 130.670 1.00 77.10  ? 236 SER B OG  1 
ATOM   2999  N N   . ILE B 2 215 ? 159.912 113.320 134.149 1.00 66.25  ? 237 ILE B N   1 
ATOM   3000  C CA  . ILE B 2 215 ? 159.058 114.153 134.982 1.00 66.25  ? 237 ILE B CA  1 
ATOM   3001  C C   . ILE B 2 215 ? 159.890 115.268 135.598 1.00 66.25  ? 237 ILE B C   1 
ATOM   3002  O O   . ILE B 2 215 ? 161.117 115.189 135.686 1.00 66.25  ? 237 ILE B O   1 
ATOM   3003  C CB  . ILE B 2 215 ? 158.345 113.345 136.090 1.00 66.25  ? 237 ILE B CB  1 
ATOM   3004  C CG1 . ILE B 2 215 ? 159.350 112.870 137.140 1.00 66.25  ? 237 ILE B CG1 1 
ATOM   3005  C CG2 . ILE B 2 215 ? 157.592 112.165 135.494 1.00 66.25  ? 237 ILE B CG2 1 
ATOM   3006  C CD1 . ILE B 2 215 ? 158.705 112.244 138.357 1.00 66.25  ? 237 ILE B CD1 1 
ATOM   3007  N N   . LEU B 2 216 ? 159.196 116.323 136.023 1.00 63.43  ? 238 LEU B N   1 
ATOM   3008  C CA  . LEU B 2 216 ? 159.835 117.459 136.683 1.00 63.43  ? 238 LEU B CA  1 
ATOM   3009  C C   . LEU B 2 216 ? 158.854 118.017 137.703 1.00 63.43  ? 238 LEU B C   1 
ATOM   3010  O O   . LEU B 2 216 ? 157.846 118.624 137.328 1.00 63.43  ? 238 LEU B O   1 
ATOM   3011  C CB  . LEU B 2 216 ? 160.244 118.529 135.675 1.00 63.43  ? 238 LEU B CB  1 
ATOM   3012  C CG  . LEU B 2 216 ? 161.604 118.361 134.997 1.00 63.43  ? 238 LEU B CG  1 
ATOM   3013  C CD1 . LEU B 2 216 ? 161.914 119.569 134.130 1.00 63.43  ? 238 LEU B CD1 1 
ATOM   3014  C CD2 . LEU B 2 216 ? 162.694 118.147 136.032 1.00 63.43  ? 238 LEU B CD2 1 
ATOM   3015  N N   . LYS B 2 217 ? 159.147 117.813 138.984 1.00 61.30  ? 239 LYS B N   1 
ATOM   3016  C CA  . LYS B 2 217 ? 158.274 118.287 140.047 1.00 61.30  ? 239 LYS B CA  1 
ATOM   3017  C C   . LYS B 2 217 ? 158.552 119.756 140.338 1.00 61.30  ? 239 LYS B C   1 
ATOM   3018  O O   . LYS B 2 217 ? 159.708 120.156 140.512 1.00 61.30  ? 239 LYS B O   1 
ATOM   3019  C CB  . LYS B 2 217 ? 158.471 117.449 141.310 1.00 61.30  ? 239 LYS B CB  1 
ATOM   3020  C CG  . LYS B 2 217 ? 157.658 117.920 142.504 1.00 61.30  ? 239 LYS B CG  1 
ATOM   3021  C CD  . LYS B 2 217 ? 157.937 117.065 143.729 1.00 61.30  ? 239 LYS B CD  1 
ATOM   3022  C CE  . LYS B 2 217 ? 157.136 117.540 144.929 1.00 61.30  ? 239 LYS B CE  1 
ATOM   3023  N NZ  . LYS B 2 217 ? 157.416 116.721 146.140 1.00 61.30  ? 239 LYS B NZ  1 
ATOM   3024  N N   . LEU B 2 218 ? 157.494 120.557 140.387 1.00 58.83  ? 240 LEU B N   1 
ATOM   3025  C CA  . LEU B 2 218 ? 157.600 121.976 140.688 1.00 58.83  ? 240 LEU B CA  1 
ATOM   3026  C C   . LEU B 2 218 ? 157.317 122.227 142.163 1.00 58.83  ? 240 LEU B C   1 
ATOM   3027  O O   . LEU B 2 218 ? 156.592 121.471 142.814 1.00 58.83  ? 240 LEU B O   1 
ATOM   3028  C CB  . LEU B 2 218 ? 156.632 122.791 139.828 1.00 58.83  ? 240 LEU B CB  1 
ATOM   3029  C CG  . LEU B 2 218 ? 156.858 122.719 138.318 1.00 58.83  ? 240 LEU B CG  1 
ATOM   3030  C CD1 . LEU B 2 218 ? 155.915 123.662 137.591 1.00 58.83  ? 240 LEU B CD1 1 
ATOM   3031  C CD2 . LEU B 2 218 ? 158.304 123.037 137.981 1.00 58.83  ? 240 LEU B CD2 1 
ATOM   3032  N N   . SER B 2 219 ? 157.902 123.302 142.686 1.00 60.45  ? 241 SER B N   1 
ATOM   3033  C CA  . SER B 2 219 ? 157.731 123.665 144.088 1.00 60.45  ? 241 SER B CA  1 
ATOM   3034  C C   . SER B 2 219 ? 157.790 125.178 144.206 1.00 60.45  ? 241 SER B C   1 
ATOM   3035  O O   . SER B 2 219 ? 158.780 125.794 143.800 1.00 60.45  ? 241 SER B O   1 
ATOM   3036  C CB  . SER B 2 219 ? 158.806 123.015 144.963 1.00 60.45  ? 241 SER B CB  1 
ATOM   3037  O OG  . SER B 2 219 ? 158.984 121.649 144.631 1.00 60.45  ? 241 SER B OG  1 
ATOM   3038  N N   . TRP B 2 220 ? 156.735 125.773 144.759 1.00 60.33  ? 242 TRP B N   1 
ATOM   3039  C CA  . TRP B 2 220 ? 156.681 127.214 144.942 1.00 60.33  ? 242 TRP B CA  1 
ATOM   3040  C C   . TRP B 2 220 ? 155.853 127.524 146.179 1.00 60.33  ? 242 TRP B C   1 
ATOM   3041  O O   . TRP B 2 220 ? 155.154 126.662 146.716 1.00 60.33  ? 242 TRP B O   1 
ATOM   3042  C CB  . TRP B 2 220 ? 156.093 127.919 143.713 1.00 60.33  ? 242 TRP B CB  1 
ATOM   3043  C CG  . TRP B 2 220 ? 154.627 127.682 143.532 1.00 60.33  ? 242 TRP B CG  1 
ATOM   3044  C CD1 . TRP B 2 220 ? 153.608 128.475 143.972 1.00 60.33  ? 242 TRP B CD1 1 
ATOM   3045  C CD2 . TRP B 2 220 ? 154.013 126.577 142.859 1.00 60.33  ? 242 TRP B CD2 1 
ATOM   3046  N NE1 . TRP B 2 220 ? 152.398 127.932 143.617 1.00 60.33  ? 242 TRP B NE1 1 
ATOM   3047  C CE2 . TRP B 2 220 ? 152.619 126.766 142.932 1.00 60.33  ? 242 TRP B CE2 1 
ATOM   3048  C CE3 . TRP B 2 220 ? 154.507 125.446 142.203 1.00 60.33  ? 242 TRP B CE3 1 
ATOM   3049  C CZ2 . TRP B 2 220 ? 151.714 125.867 142.374 1.00 60.33  ? 242 TRP B CZ2 1 
ATOM   3050  C CZ3 . TRP B 2 220 ? 153.606 124.555 141.649 1.00 60.33  ? 242 TRP B CZ3 1 
ATOM   3051  C CH2 . TRP B 2 220 ? 152.226 124.770 141.738 1.00 60.33  ? 242 TRP B CH2 1 
ATOM   3052  N N   . VAL B 2 221 ? 155.943 128.773 146.627 1.00 66.99  ? 243 VAL B N   1 
ATOM   3053  C CA  . VAL B 2 221 ? 155.197 129.258 147.780 1.00 66.99  ? 243 VAL B CA  1 
ATOM   3054  C C   . VAL B 2 221 ? 154.370 130.461 147.352 1.00 66.99  ? 243 VAL B C   1 
ATOM   3055  O O   . VAL B 2 221 ? 154.775 131.222 146.466 1.00 66.99  ? 243 VAL B O   1 
ATOM   3056  C CB  . VAL B 2 221 ? 156.129 129.620 148.955 1.00 66.99  ? 243 VAL B CB  1 
ATOM   3057  C CG1 . VAL B 2 221 ? 156.869 128.385 149.443 1.00 66.99  ? 243 VAL B CG1 1 
ATOM   3058  C CG2 . VAL B 2 221 ? 157.114 130.701 148.541 1.00 66.99  ? 243 VAL B CG2 1 
ATOM   3059  N N   . SER B 2 222 ? 153.206 130.622 147.973 1.00 64.63  ? 244 SER B N   1 
ATOM   3060  C CA  . SER B 2 222 ? 152.297 131.715 147.670 1.00 64.63  ? 244 SER B CA  1 
ATOM   3061  C C   . SER B 2 222 ? 151.985 132.496 148.938 1.00 64.63  ? 244 SER B C   1 
ATOM   3062  O O   . SER B 2 222 ? 151.945 131.936 150.038 1.00 64.63  ? 244 SER B O   1 
ATOM   3063  C CB  . SER B 2 222 ? 150.995 131.200 147.042 1.00 64.63  ? 244 SER B CB  1 
ATOM   3064  O OG  . SER B 2 222 ? 151.259 130.225 146.049 1.00 64.63  ? 244 SER B OG  1 
ATOM   3065  N N   . SER B 2 223 ? 151.764 133.801 148.775 1.00 64.21  ? 245 SER B N   1 
ATOM   3066  C CA  . SER B 2 223 ? 151.421 134.642 149.916 1.00 64.21  ? 245 SER B CA  1 
ATOM   3067  C C   . SER B 2 223 ? 150.002 134.357 150.393 1.00 64.21  ? 245 SER B C   1 
ATOM   3068  O O   . SER B 2 223 ? 149.789 133.940 151.538 1.00 64.21  ? 245 SER B O   1 
ATOM   3069  C CB  . SER B 2 223 ? 151.585 136.117 149.547 1.00 64.21  ? 245 SER B CB  1 
ATOM   3070  O OG  . SER B 2 223 ? 152.793 136.334 148.839 1.00 64.21  ? 245 SER B OG  1 
ATOM   3071  N N   . GLY B 2 224 ? 149.018 134.571 149.522 1.00 67.31  ? 246 GLY B N   1 
ATOM   3072  C CA  . GLY B 2 224 ? 147.636 134.294 149.864 1.00 67.31  ? 246 GLY B CA  1 
ATOM   3073  C C   . GLY B 2 224 ? 147.095 135.094 151.024 1.00 67.31  ? 246 GLY B C   1 
ATOM   3074  O O   . GLY B 2 224 ? 146.145 134.653 151.677 1.00 67.31  ? 246 GLY B O   1 
ATOM   3075  N N   . LEU B 2 225 ? 147.677 136.264 151.301 1.00 67.72  ? 247 LEU B N   1 
ATOM   3076  C CA  . LEU B 2 225 ? 147.250 137.122 152.408 1.00 67.72  ? 247 LEU B CA  1 
ATOM   3077  C C   . LEU B 2 225 ? 147.301 136.375 153.739 1.00 67.72  ? 247 LEU B C   1 
ATOM   3078  O O   . LEU B 2 225 ? 146.437 136.543 154.601 1.00 67.72  ? 247 LEU B O   1 
ATOM   3079  C CB  . LEU B 2 225 ? 145.853 137.697 152.161 1.00 67.72  ? 247 LEU B CB  1 
ATOM   3080  C CG  . LEU B 2 225 ? 145.734 138.885 151.203 1.00 67.72  ? 247 LEU B CG  1 
ATOM   3081  C CD1 . LEU B 2 225 ? 145.809 138.434 149.752 1.00 67.72  ? 247 LEU B CD1 1 
ATOM   3082  C CD2 . LEU B 2 225 ? 144.444 139.642 151.463 1.00 67.72  ? 247 LEU B CD2 1 
ATOM   3083  N N   . GLY B 2 226 ? 148.324 135.540 153.906 1.00 70.88  ? 248 GLY B N   1 
ATOM   3084  C CA  . GLY B 2 226 ? 148.447 134.751 155.115 1.00 70.88  ? 248 GLY B CA  1 
ATOM   3085  C C   . GLY B 2 226 ? 147.562 133.529 155.159 1.00 70.88  ? 248 GLY B C   1 
ATOM   3086  O O   . GLY B 2 226 ? 147.183 133.086 156.248 1.00 70.88  ? 248 GLY B O   1 
ATOM   3087  N N   . GLY B 2 227 ? 147.216 132.968 154.004 1.00 71.21  ? 249 GLY B N   1 
ATOM   3088  C CA  . GLY B 2 227 ? 146.359 131.802 153.955 1.00 71.21  ? 249 GLY B CA  1 
ATOM   3089  C C   . GLY B 2 227 ? 144.879 132.094 153.897 1.00 71.21  ? 249 GLY B C   1 
ATOM   3090  O O   . GLY B 2 227 ? 144.080 131.256 154.329 1.00 71.21  ? 249 GLY B O   1 
ATOM   3091  N N   . LEU B 2 228 ? 144.484 133.255 153.376 1.00 62.66  ? 250 LEU B N   1 
ATOM   3092  C CA  . LEU B 2 228 ? 143.077 133.632 153.330 1.00 62.66  ? 250 LEU B CA  1 
ATOM   3093  C C   . LEU B 2 228 ? 142.416 133.297 152.000 1.00 62.66  ? 250 LEU B C   1 
ATOM   3094  O O   . LEU B 2 228 ? 141.229 132.952 151.979 1.00 62.66  ? 250 LEU B O   1 
ATOM   3095  C CB  . LEU B 2 228 ? 142.928 135.130 153.613 1.00 62.66  ? 250 LEU B CB  1 
ATOM   3096  C CG  . LEU B 2 228 ? 141.505 135.689 153.674 1.00 62.66  ? 250 LEU B CG  1 
ATOM   3097  C CD1 . LEU B 2 228 ? 140.685 134.953 154.719 1.00 62.66  ? 250 LEU B CD1 1 
ATOM   3098  C CD2 . LEU B 2 228 ? 141.529 137.182 153.960 1.00 62.66  ? 250 LEU B CD2 1 
ATOM   3099  N N   . LEU B 2 229 ? 143.151 133.381 150.896 1.00 62.86  ? 251 LEU B N   1 
ATOM   3100  C CA  . LEU B 2 229 ? 142.601 133.170 149.564 1.00 62.86  ? 251 LEU B CA  1 
ATOM   3101  C C   . LEU B 2 229 ? 143.145 131.877 148.974 1.00 62.86  ? 251 LEU B C   1 
ATOM   3102  O O   . LEU B 2 229 ? 144.362 131.671 148.933 1.00 62.86  ? 251 LEU B O   1 
ATOM   3103  C CB  . LEU B 2 229 ? 142.934 134.346 148.643 1.00 62.86  ? 251 LEU B CB  1 
ATOM   3104  C CG  . LEU B 2 229 ? 142.458 135.725 149.099 1.00 62.86  ? 251 LEU B CG  1 
ATOM   3105  C CD1 . LEU B 2 229 ? 142.796 136.779 148.056 1.00 62.86  ? 251 LEU B CD1 1 
ATOM   3106  C CD2 . LEU B 2 229 ? 140.967 135.704 149.383 1.00 62.86  ? 251 LEU B CD2 1 
ATOM   3107  N N   . ASP B 2 230 ? 142.241 131.012 148.518 1.00 65.73  ? 252 ASP B N   1 
ATOM   3108  C CA  . ASP B 2 230 ? 142.623 129.804 147.796 1.00 65.73  ? 252 ASP B CA  1 
ATOM   3109  C C   . ASP B 2 230 ? 142.938 130.187 146.355 1.00 65.73  ? 252 ASP B C   1 
ATOM   3110  O O   . ASP B 2 230 ? 142.032 130.494 145.575 1.00 65.73  ? 252 ASP B O   1 
ATOM   3111  C CB  . ASP B 2 230 ? 141.509 128.764 147.860 1.00 65.73  ? 252 ASP B CB  1 
ATOM   3112  C CG  . ASP B 2 230 ? 141.205 128.324 149.278 1.00 65.73  ? 252 ASP B CG  1 
ATOM   3113  O OD1 . ASP B 2 230 ? 142.114 128.393 150.131 1.00 65.73  ? 252 ASP B OD1 1 
ATOM   3114  O OD2 . ASP B 2 230 ? 140.057 127.908 149.539 1.00 65.73  ? 252 ASP B OD2 1 
ATOM   3115  N N   . LEU B 2 231 ? 144.219 130.174 146.000 1.00 56.02  ? 253 LEU B N   1 
ATOM   3116  C CA  . LEU B 2 231 ? 144.676 130.658 144.705 1.00 56.02  ? 253 LEU B CA  1 
ATOM   3117  C C   . LEU B 2 231 ? 144.968 129.488 143.775 1.00 56.02  ? 253 LEU B C   1 
ATOM   3118  O O   . LEU B 2 231 ? 145.702 128.565 144.142 1.00 56.02  ? 253 LEU B O   1 
ATOM   3119  C CB  . LEU B 2 231 ? 145.927 131.523 144.862 1.00 56.02  ? 253 LEU B CB  1 
ATOM   3120  C CG  . LEU B 2 231 ? 145.828 132.710 145.822 1.00 56.02  ? 253 LEU B CG  1 
ATOM   3121  C CD1 . LEU B 2 231 ? 147.163 133.431 145.918 1.00 56.02  ? 253 LEU B CD1 1 
ATOM   3122  C CD2 . LEU B 2 231 ? 144.731 133.665 145.383 1.00 56.02  ? 253 LEU B CD2 1 
ATOM   3123  N N   . LYS B 2 232 ? 144.392 129.531 142.578 1.00 58.30  ? 254 LYS B N   1 
ATOM   3124  C CA  . LYS B 2 232 ? 144.736 128.602 141.513 1.00 58.30  ? 254 LYS B CA  1 
ATOM   3125  C C   . LYS B 2 232 ? 145.774 129.244 140.600 1.00 58.30  ? 254 LYS B C   1 
ATOM   3126  O O   . LYS B 2 232 ? 145.825 130.467 140.452 1.00 58.30  ? 254 LYS B O   1 
ATOM   3127  C CB  . LYS B 2 232 ? 143.498 128.193 140.711 1.00 58.30  ? 254 LYS B CB  1 
ATOM   3128  C CG  . LYS B 2 232 ? 142.917 129.288 139.835 1.00 58.30  ? 254 LYS B CG  1 
ATOM   3129  C CD  . LYS B 2 232 ? 141.809 128.743 138.948 1.00 58.30  ? 254 LYS B CD  1 
ATOM   3130  C CE  . LYS B 2 232 ? 141.303 129.797 137.978 1.00 58.30  ? 254 LYS B CE  1 
ATOM   3131  N NZ  . LYS B 2 232 ? 140.241 129.262 137.083 1.00 58.30  ? 254 LYS B NZ  1 
ATOM   3132  N N   . SER B 2 233 ? 146.609 128.406 139.994 1.00 62.40  ? 255 SER B N   1 
ATOM   3133  C CA  . SER B 2 233 ? 147.774 128.877 139.263 1.00 62.40  ? 255 SER B CA  1 
ATOM   3134  C C   . SER B 2 233 ? 147.714 128.456 137.801 1.00 62.40  ? 255 SER B C   1 
ATOM   3135  O O   . SER B 2 233 ? 146.950 127.567 137.413 1.00 62.40  ? 255 SER B O   1 
ATOM   3136  C CB  . SER B 2 233 ? 149.065 128.351 139.900 1.00 62.40  ? 255 SER B CB  1 
ATOM   3137  O OG  . SER B 2 233 ? 148.948 126.977 140.226 1.00 62.40  ? 255 SER B OG  1 
ATOM   3138  N N   . ASP B 2 234 ? 148.540 129.118 136.992 1.00 63.10  ? 256 ASP B N   1 
ATOM   3139  C CA  . ASP B 2 234 ? 148.702 128.805 135.577 1.00 63.10  ? 256 ASP B CA  1 
ATOM   3140  C C   . ASP B 2 234 ? 150.186 128.614 135.305 1.00 63.10  ? 256 ASP B C   1 
ATOM   3141  O O   . ASP B 2 234 ? 150.982 129.531 135.532 1.00 63.10  ? 256 ASP B O   1 
ATOM   3142  C CB  . ASP B 2 234 ? 148.128 129.915 134.693 1.00 63.10  ? 256 ASP B CB  1 
ATOM   3143  C CG  . ASP B 2 234 ? 148.131 129.549 133.223 1.00 63.10  ? 256 ASP B CG  1 
ATOM   3144  O OD1 . ASP B 2 234 ? 148.286 128.352 132.906 1.00 63.10  ? 256 ASP B OD1 1 
ATOM   3145  O OD2 . ASP B 2 234 ? 147.982 130.461 132.383 1.00 63.10  ? 256 ASP B OD2 1 
ATOM   3146  N N   . ILE B 2 235 ? 150.556 127.432 134.819 1.00 64.67  ? 257 ILE B N   1 
ATOM   3147  C CA  . ILE B 2 235 ? 151.951 127.049 134.637 1.00 64.67  ? 257 ILE B CA  1 
ATOM   3148  C C   . ILE B 2 235 ? 152.252 126.972 133.147 1.00 64.67  ? 257 ILE B C   1 
ATOM   3149  O O   . ILE B 2 235 ? 151.520 126.322 132.391 1.00 64.67  ? 257 ILE B O   1 
ATOM   3150  C CB  . ILE B 2 235 ? 152.259 125.710 135.329 1.00 64.67  ? 257 ILE B CB  1 
ATOM   3151  C CG1 . ILE B 2 235 ? 151.968 125.808 136.828 1.00 64.67  ? 257 ILE B CG1 1 
ATOM   3152  C CG2 . ILE B 2 235 ? 153.703 125.304 135.087 1.00 64.67  ? 257 ILE B CG2 1 
ATOM   3153  C CD1 . ILE B 2 235 ? 152.205 124.519 137.581 1.00 64.67  ? 257 ILE B CD1 1 
ATOM   3154  N N   . GLN B 2 236 ? 153.329 127.633 132.730 1.00 59.49  ? 258 GLN B N   1 
ATOM   3155  C CA  . GLN B 2 236 ? 153.813 127.584 131.359 1.00 59.49  ? 258 GLN B CA  1 
ATOM   3156  C C   . GLN B 2 236 ? 155.260 127.112 131.351 1.00 59.49  ? 258 GLN B C   1 
ATOM   3157  O O   . GLN B 2 236 ? 156.068 127.549 132.176 1.00 59.49  ? 258 GLN B O   1 
ATOM   3158  C CB  . GLN B 2 236 ? 153.707 128.953 130.680 1.00 59.49  ? 258 GLN B CB  1 
ATOM   3159  C CG  . GLN B 2 236 ? 152.295 129.345 130.286 1.00 59.49  ? 258 GLN B CG  1 
ATOM   3160  C CD  . GLN B 2 236 ? 152.255 130.621 129.469 1.00 59.49  ? 258 GLN B CD  1 
ATOM   3161  O OE1 . GLN B 2 236 ? 153.268 131.302 129.310 1.00 59.49  ? 258 GLN B OE1 1 
ATOM   3162  N NE2 . GLN B 2 236 ? 151.081 130.951 128.946 1.00 59.49  ? 258 GLN B NE2 1 
ATOM   3163  N N   . TYR B 2 237 ? 155.583 126.220 130.418 1.00 59.23  ? 259 TYR B N   1 
ATOM   3164  C CA  . TYR B 2 237 ? 156.919 125.657 130.310 1.00 59.23  ? 259 TYR B CA  1 
ATOM   3165  C C   . TYR B 2 237 ? 157.385 125.695 128.862 1.00 59.23  ? 259 TYR B C   1 
ATOM   3166  O O   . TYR B 2 237 ? 156.575 125.697 127.931 1.00 59.23  ? 259 TYR B O   1 
ATOM   3167  C CB  . TYR B 2 237 ? 156.966 124.215 130.836 1.00 59.23  ? 259 TYR B CB  1 
ATOM   3168  C CG  . TYR B 2 237 ? 156.292 123.202 129.938 1.00 59.23  ? 259 TYR B CG  1 
ATOM   3169  C CD1 . TYR B 2 237 ? 154.910 123.067 129.924 1.00 59.23  ? 259 TYR B CD1 1 
ATOM   3170  C CD2 . TYR B 2 237 ? 157.037 122.372 129.111 1.00 59.23  ? 259 TYR B CD2 1 
ATOM   3171  C CE1 . TYR B 2 237 ? 154.291 122.141 129.108 1.00 59.23  ? 259 TYR B CE1 1 
ATOM   3172  C CE2 . TYR B 2 237 ? 156.426 121.443 128.291 1.00 59.23  ? 259 TYR B CE2 1 
ATOM   3173  C CZ  . TYR B 2 237 ? 155.053 121.332 128.294 1.00 59.23  ? 259 TYR B CZ  1 
ATOM   3174  O OH  . TYR B 2 237 ? 154.441 120.407 127.480 1.00 59.23  ? 259 TYR B OH  1 
ATOM   3175  N N   . ARG B 2 238 ? 158.703 125.721 128.685 1.00 68.67  ? 260 ARG B N   1 
ATOM   3176  C CA  . ARG B 2 238 ? 159.307 125.747 127.360 1.00 68.67  ? 260 ARG B CA  1 
ATOM   3177  C C   . ARG B 2 238 ? 160.757 125.305 127.483 1.00 68.67  ? 260 ARG B C   1 
ATOM   3178  O O   . ARG B 2 238 ? 161.312 125.223 128.582 1.00 68.67  ? 260 ARG B O   1 
ATOM   3179  C CB  . ARG B 2 238 ? 159.212 127.138 126.727 1.00 68.67  ? 260 ARG B CB  1 
ATOM   3180  C CG  . ARG B 2 238 ? 160.192 128.143 127.309 1.00 68.67  ? 260 ARG B CG  1 
ATOM   3181  C CD  . ARG B 2 238 ? 160.340 129.361 126.413 1.00 68.67  ? 260 ARG B CD  1 
ATOM   3182  N NE  . ARG B 2 238 ? 161.411 130.242 126.868 1.00 68.67  ? 260 ARG B NE  1 
ATOM   3183  C CZ  . ARG B 2 238 ? 161.759 131.371 126.260 1.00 68.67  ? 260 ARG B CZ  1 
ATOM   3184  N NH1 . ARG B 2 238 ? 161.119 131.762 125.167 1.00 68.67  ? 260 ARG B NH1 1 
ATOM   3185  N NH2 . ARG B 2 238 ? 162.747 132.110 126.746 1.00 68.67  ? 260 ARG B NH2 1 
ATOM   3186  N N   . THR B 2 239 ? 161.368 125.025 126.336 1.00 68.28  ? 261 THR B N   1 
ATOM   3187  C CA  . THR B 2 239 ? 162.771 124.638 126.290 1.00 68.28  ? 261 THR B CA  1 
ATOM   3188  C C   . THR B 2 239 ? 163.643 125.890 126.366 1.00 68.28  ? 261 THR B C   1 
ATOM   3189  O O   . THR B 2 239 ? 163.166 126.996 126.636 1.00 68.28  ? 261 THR B O   1 
ATOM   3190  C CB  . THR B 2 239 ? 163.057 123.817 125.035 1.00 68.28  ? 261 THR B CB  1 
ATOM   3191  O OG1 . THR B 2 239 ? 162.787 124.610 123.872 1.00 68.28  ? 261 THR B OG1 1 
ATOM   3192  C CG2 . THR B 2 239 ? 162.185 122.572 125.004 1.00 68.28  ? 261 THR B CG2 1 
ATOM   3193  N N   . LYS B 2 240 ? 164.943 125.729 126.126 1.00 75.64  ? 262 LYS B N   1 
ATOM   3194  C CA  . LYS B 2 240 ? 165.868 126.853 126.173 1.00 75.64  ? 262 LYS B CA  1 
ATOM   3195  C C   . LYS B 2 240 ? 166.123 127.475 124.807 1.00 75.64  ? 262 LYS B C   1 
ATOM   3196  O O   . LYS B 2 240 ? 166.578 128.622 124.740 1.00 75.64  ? 262 LYS B O   1 
ATOM   3197  C CB  . LYS B 2 240 ? 167.201 126.415 126.788 1.00 75.64  ? 262 LYS B CB  1 
ATOM   3198  C CG  . LYS B 2 240 ? 167.994 127.548 127.418 1.00 75.64  ? 262 LYS B CG  1 
ATOM   3199  C CD  . LYS B 2 240 ? 169.242 127.032 128.111 1.00 75.64  ? 262 LYS B CD  1 
ATOM   3200  C CE  . LYS B 2 240 ? 169.894 128.120 128.949 1.00 75.64  ? 262 LYS B CE  1 
ATOM   3201  N NZ  . LYS B 2 240 ? 171.043 127.599 129.741 1.00 75.64  ? 262 LYS B NZ  1 
ATOM   3202  N N   . ASP B 2 241 ? 165.838 126.754 123.723 1.00 83.11  ? 263 ASP B N   1 
ATOM   3203  C CA  . ASP B 2 241 ? 166.077 127.261 122.378 1.00 83.11  ? 263 ASP B CA  1 
ATOM   3204  C C   . ASP B 2 241 ? 164.820 127.776 121.691 1.00 83.11  ? 263 ASP B C   1 
ATOM   3205  O O   . ASP B 2 241 ? 164.932 128.551 120.736 1.00 83.11  ? 263 ASP B O   1 
ATOM   3206  C CB  . ASP B 2 241 ? 166.711 126.171 121.506 1.00 83.11  ? 263 ASP B CB  1 
ATOM   3207  C CG  . ASP B 2 241 ? 165.826 124.948 121.368 1.00 83.11  ? 263 ASP B CG  1 
ATOM   3208  O OD1 . ASP B 2 241 ? 165.057 124.661 122.309 1.00 83.11  ? 263 ASP B OD1 1 
ATOM   3209  O OD2 . ASP B 2 241 ? 165.899 124.273 120.320 1.00 83.11  ? 263 ASP B OD2 1 
ATOM   3210  N N   . ALA B 2 242 ? 163.639 127.371 122.147 1.00 79.72  ? 264 ALA B N   1 
ATOM   3211  C CA  . ALA B 2 242 ? 162.392 127.794 121.531 1.00 79.72  ? 264 ALA B CA  1 
ATOM   3212  C C   . ALA B 2 242 ? 161.873 129.067 122.188 1.00 79.72  ? 264 ALA B C   1 
ATOM   3213  O O   . ALA B 2 242 ? 162.139 129.340 123.361 1.00 79.72  ? 264 ALA B O   1 
ATOM   3214  C CB  . ALA B 2 242 ? 161.337 126.691 121.629 1.00 79.72  ? 264 ALA B CB  1 
ATOM   3215  N N   . SER B 2 243 ? 161.123 129.848 121.412 1.00 79.29  ? 265 SER B N   1 
ATOM   3216  C CA  . SER B 2 243 ? 160.553 131.099 121.894 1.00 79.29  ? 265 SER B CA  1 
ATOM   3217  C C   . SER B 2 243 ? 159.093 130.977 122.299 1.00 79.29  ? 265 SER B C   1 
ATOM   3218  O O   . SER B 2 243 ? 158.633 131.745 123.151 1.00 79.29  ? 265 SER B O   1 
ATOM   3219  C CB  . SER B 2 243 ? 160.686 132.190 120.825 1.00 79.29  ? 265 SER B CB  1 
ATOM   3220  O OG  . SER B 2 243 ? 160.538 133.479 121.393 1.00 79.29  ? 265 SER B OG  1 
ATOM   3221  N N   . THR B 2 244 ? 158.354 130.039 121.714 1.00 77.01  ? 266 THR B N   1 
ATOM   3222  C CA  . THR B 2 244 ? 156.954 129.856 122.060 1.00 77.01  ? 266 THR B CA  1 
ATOM   3223  C C   . THR B 2 244 ? 156.822 129.134 123.396 1.00 77.01  ? 266 THR B C   1 
ATOM   3224  O O   . THR B 2 244 ? 157.685 128.345 123.791 1.00 77.01  ? 266 THR B O   1 
ATOM   3225  C CB  . THR B 2 244 ? 156.225 129.070 120.969 1.00 77.01  ? 266 THR B CB  1 
ATOM   3226  O OG1 . THR B 2 244 ? 154.887 128.785 121.394 1.00 77.01  ? 266 THR B OG1 1 
ATOM   3227  C CG2 . THR B 2 244 ? 156.949 127.763 120.676 1.00 77.01  ? 266 THR B CG2 1 
ATOM   3228  N N   . TRP B 2 245 ? 155.727 129.418 124.095 1.00 67.38  ? 267 TRP B N   1 
ATOM   3229  C CA  . TRP B 2 245 ? 155.448 128.836 125.400 1.00 67.38  ? 267 TRP B CA  1 
ATOM   3230  C C   . TRP B 2 245 ? 154.286 127.860 125.285 1.00 67.38  ? 267 TRP B C   1 
ATOM   3231  O O   . TRP B 2 245 ? 153.237 128.200 124.727 1.00 67.38  ? 267 TRP B O   1 
ATOM   3232  C CB  . TRP B 2 245 ? 155.125 129.924 126.426 1.00 67.38  ? 267 TRP B CB  1 
ATOM   3233  C CG  . TRP B 2 245 ? 156.272 130.844 126.704 1.00 67.38  ? 267 TRP B CG  1 
ATOM   3234  C CD1 . TRP B 2 245 ? 156.635 131.941 125.981 1.00 67.38  ? 267 TRP B CD1 1 
ATOM   3235  C CD2 . TRP B 2 245 ? 157.207 130.749 127.786 1.00 67.38  ? 267 TRP B CD2 1 
ATOM   3236  N NE1 . TRP B 2 245 ? 157.739 132.535 126.544 1.00 67.38  ? 267 TRP B NE1 1 
ATOM   3237  C CE2 . TRP B 2 245 ? 158.109 131.822 127.653 1.00 67.38  ? 267 TRP B CE2 1 
ATOM   3238  C CE3 . TRP B 2 245 ? 157.368 129.860 128.853 1.00 67.38  ? 267 TRP B CE3 1 
ATOM   3239  C CZ2 . TRP B 2 245 ? 159.156 132.031 128.547 1.00 67.38  ? 267 TRP B CZ2 1 
ATOM   3240  C CZ3 . TRP B 2 245 ? 158.408 130.069 129.738 1.00 67.38  ? 267 TRP B CZ3 1 
ATOM   3241  C CH2 . TRP B 2 245 ? 159.289 131.146 129.580 1.00 67.38  ? 267 TRP B CH2 1 
ATOM   3242  N N   . ILE B 2 246 ? 154.476 126.654 125.810 1.00 66.64  ? 268 ILE B N   1 
ATOM   3243  C CA  . ILE B 2 246 ? 153.441 125.627 125.828 1.00 66.64  ? 268 ILE B CA  1 
ATOM   3244  C C   . ILE B 2 246 ? 152.761 125.670 127.188 1.00 66.64  ? 268 ILE B C   1 
ATOM   3245  O O   . ILE B 2 246 ? 153.424 125.559 128.227 1.00 66.64  ? 268 ILE B O   1 
ATOM   3246  C CB  . ILE B 2 246 ? 154.025 124.235 125.543 1.00 66.64  ? 268 ILE B CB  1 
ATOM   3247  C CG1 . ILE B 2 246 ? 154.870 124.264 124.268 1.00 66.64  ? 268 ILE B CG1 1 
ATOM   3248  C CG2 . ILE B 2 246 ? 152.911 123.207 125.425 1.00 66.64  ? 268 ILE B CG2 1 
ATOM   3249  C CD1 . ILE B 2 246 ? 155.551 122.949 123.959 1.00 66.64  ? 268 ILE B CD1 1 
ATOM   3250  N N   . GLN B 2 247 ? 151.442 125.829 127.187 1.00 60.87  ? 269 GLN B N   1 
ATOM   3251  C CA  . GLN B 2 247 ? 150.665 125.941 128.414 1.00 60.87  ? 269 GLN B CA  1 
ATOM   3252  C C   . GLN B 2 247 ? 149.996 124.609 128.725 1.00 60.87  ? 269 GLN B C   1 
ATOM   3253  O O   . GLN B 2 247 ? 149.407 123.981 127.838 1.00 60.87  ? 269 GLN B O   1 
ATOM   3254  C CB  . GLN B 2 247 ? 149.613 127.044 128.294 1.00 60.87  ? 269 GLN B CB  1 
ATOM   3255  C CG  . GLN B 2 247 ? 148.774 127.237 129.546 1.00 60.87  ? 269 GLN B CG  1 
ATOM   3256  C CD  . GLN B 2 247 ? 147.746 128.339 129.393 1.00 60.87  ? 269 GLN B CD  1 
ATOM   3257  O OE1 . GLN B 2 247 ? 147.675 128.998 128.357 1.00 60.87  ? 269 GLN B OE1 1 
ATOM   3258  N NE2 . GLN B 2 247 ? 146.940 128.544 130.429 1.00 60.87  ? 269 GLN B NE2 1 
ATOM   3259  N N   . VAL B 2 248 ? 150.090 124.184 129.980 1.00 64.51  ? 270 VAL B N   1 
ATOM   3260  C CA  . VAL B 2 248 ? 149.448 122.956 130.441 1.00 64.51  ? 270 VAL B CA  1 
ATOM   3261  C C   . VAL B 2 248 ? 147.944 123.200 130.510 1.00 64.51  ? 270 VAL B C   1 
ATOM   3262  O O   . VAL B 2 248 ? 147.514 124.359 130.600 1.00 64.51  ? 270 VAL B O   1 
ATOM   3263  C CB  . VAL B 2 248 ? 150.008 122.512 131.802 1.00 64.51  ? 270 VAL B CB  1 
ATOM   3264  C CG1 . VAL B 2 248 ? 151.492 122.205 131.689 1.00 64.51  ? 270 VAL B CG1 1 
ATOM   3265  C CG2 . VAL B 2 248 ? 149.758 123.581 132.854 1.00 64.51  ? 270 VAL B CG2 1 
ATOM   3266  N N   . PRO B 2 249 ? 147.114 122.159 130.451 1.00 73.04  ? 271 PRO B N   1 
ATOM   3267  C CA  . PRO B 2 249 ? 145.665 122.368 130.574 1.00 73.04  ? 271 PRO B CA  1 
ATOM   3268  C C   . PRO B 2 249 ? 145.310 123.006 131.909 1.00 73.04  ? 271 PRO B C   1 
ATOM   3269  O O   . PRO B 2 249 ? 145.734 122.545 132.971 1.00 73.04  ? 271 PRO B O   1 
ATOM   3270  C CB  . PRO B 2 249 ? 145.091 120.952 130.450 1.00 73.04  ? 271 PRO B CB  1 
ATOM   3271  C CG  . PRO B 2 249 ? 146.124 120.194 129.690 1.00 73.04  ? 271 PRO B CG  1 
ATOM   3272  C CD  . PRO B 2 249 ? 147.443 120.762 130.123 1.00 73.04  ? 271 PRO B CD  1 
ATOM   3273  N N   . LEU B 2 250 ? 144.523 124.083 131.844 1.00 73.45  ? 272 LEU B N   1 
ATOM   3274  C CA  . LEU B 2 250 ? 144.170 124.829 133.046 1.00 73.45  ? 272 LEU B CA  1 
ATOM   3275  C C   . LEU B 2 250 ? 143.289 124.026 133.995 1.00 73.45  ? 272 LEU B C   1 
ATOM   3276  O O   . LEU B 2 250 ? 143.233 124.346 135.187 1.00 73.45  ? 272 LEU B O   1 
ATOM   3277  C CB  . LEU B 2 250 ? 143.470 126.134 132.665 1.00 73.45  ? 272 LEU B CB  1 
ATOM   3278  C CG  . LEU B 2 250 ? 143.427 127.226 133.736 1.00 73.45  ? 272 LEU B CG  1 
ATOM   3279  C CD1 . LEU B 2 250 ? 144.834 127.602 134.170 1.00 73.45  ? 272 LEU B CD1 1 
ATOM   3280  C CD2 . LEU B 2 250 ? 142.674 128.446 133.231 1.00 73.45  ? 272 LEU B CD2 1 
ATOM   3281  N N   . GLU B 2 251 ? 142.606 122.992 133.498 1.00 83.79  ? 273 GLU B N   1 
ATOM   3282  C CA  . GLU B 2 251 ? 141.762 122.180 134.369 1.00 83.79  ? 273 GLU B CA  1 
ATOM   3283  C C   . GLU B 2 251 ? 142.585 121.388 135.376 1.00 83.79  ? 273 GLU B C   1 
ATOM   3284  O O   . GLU B 2 251 ? 142.097 121.084 136.471 1.00 83.79  ? 273 GLU B O   1 
ATOM   3285  C CB  . GLU B 2 251 ? 140.900 121.235 133.533 1.00 83.79  ? 273 GLU B CB  1 
ATOM   3286  C CG  . GLU B 2 251 ? 139.830 121.932 132.712 1.00 83.79  ? 273 GLU B CG  1 
ATOM   3287  C CD  . GLU B 2 251 ? 139.051 120.971 131.838 1.00 83.79  ? 273 GLU B CD  1 
ATOM   3288  O OE1 . GLU B 2 251 ? 139.651 119.990 131.349 1.00 83.79  ? 273 GLU B OE1 1 
ATOM   3289  O OE2 . GLU B 2 251 ? 137.838 121.194 131.640 1.00 83.79  ? 273 GLU B OE2 1 
ATOM   3290  N N   . ASP B 2 252 ? 143.828 121.048 135.031 1.00 79.20  ? 274 ASP B N   1 
ATOM   3291  C CA  . ASP B 2 252 ? 144.668 120.257 135.920 1.00 79.20  ? 274 ASP B CA  1 
ATOM   3292  C C   . ASP B 2 252 ? 145.226 121.063 137.085 1.00 79.20  ? 274 ASP B C   1 
ATOM   3293  O O   . ASP B 2 252 ? 145.657 120.469 138.079 1.00 79.20  ? 274 ASP B O   1 
ATOM   3294  C CB  . ASP B 2 252 ? 145.821 119.632 135.131 1.00 79.20  ? 274 ASP B CB  1 
ATOM   3295  C CG  . ASP B 2 252 ? 145.341 118.811 133.951 1.00 79.20  ? 274 ASP B CG  1 
ATOM   3296  O OD1 . ASP B 2 252 ? 144.235 118.237 134.036 1.00 79.20  ? 274 ASP B OD1 1 
ATOM   3297  O OD2 . ASP B 2 252 ? 146.068 118.740 132.939 1.00 79.20  ? 274 ASP B OD2 1 
ATOM   3298  N N   . THR B 2 253 ? 145.231 122.389 136.989 1.00 74.27  ? 275 THR B N   1 
ATOM   3299  C CA  . THR B 2 253 ? 145.781 123.259 138.022 1.00 74.27  ? 275 THR B CA  1 
ATOM   3300  C C   . THR B 2 253 ? 144.697 124.141 138.631 1.00 74.27  ? 275 THR B C   1 
ATOM   3301  O O   . THR B 2 253 ? 144.900 125.334 138.866 1.00 74.27  ? 275 THR B O   1 
ATOM   3302  C CB  . THR B 2 253 ? 146.916 124.115 137.466 1.00 74.27  ? 275 THR B CB  1 
ATOM   3303  O OG1 . THR B 2 253 ? 146.410 124.975 136.439 1.00 74.27  ? 275 THR B OG1 1 
ATOM   3304  C CG2 . THR B 2 253 ? 148.011 123.233 136.886 1.00 74.27  ? 275 THR B CG2 1 
ATOM   3305  N N   . MET B 2 254 ? 143.527 123.561 138.894 1.00 72.92  ? 276 MET B N   1 
ATOM   3306  C CA  . MET B 2 254 ? 142.430 124.306 139.498 1.00 72.92  ? 276 MET B CA  1 
ATOM   3307  C C   . MET B 2 254 ? 142.400 124.189 141.015 1.00 72.92  ? 276 MET B C   1 
ATOM   3308  O O   . MET B 2 254 ? 141.964 125.127 141.691 1.00 72.92  ? 276 MET B O   1 
ATOM   3309  C CB  . MET B 2 254 ? 141.091 123.833 138.925 1.00 72.92  ? 276 MET B CB  1 
ATOM   3310  C CG  . MET B 2 254 ? 140.921 124.106 137.441 1.00 72.92  ? 276 MET B CG  1 
ATOM   3311  S SD  . MET B 2 254 ? 139.288 123.652 136.827 1.00 72.92  ? 276 MET B SD  1 
ATOM   3312  C CE  . MET B 2 254 ? 138.254 124.793 137.741 1.00 72.92  ? 276 MET B CE  1 
ATOM   3313  N N   . SER B 2 255 ? 142.850 123.065 141.563 1.00 65.48  ? 277 SER B N   1 
ATOM   3314  C CA  . SER B 2 255 ? 142.827 122.878 143.006 1.00 65.48  ? 277 SER B CA  1 
ATOM   3315  C C   . SER B 2 255 ? 143.961 123.667 143.661 1.00 65.48  ? 277 SER B C   1 
ATOM   3316  O O   . SER B 2 255 ? 145.049 123.778 143.091 1.00 65.48  ? 277 SER B O   1 
ATOM   3317  C CB  . SER B 2 255 ? 142.956 121.398 143.358 1.00 65.48  ? 277 SER B CB  1 
ATOM   3318  O OG  . SER B 2 255 ? 142.121 120.604 142.533 1.00 65.48  ? 277 SER B OG  1 
ATOM   3319  N N   . PRO B 2 256 ? 143.730 124.229 144.848 1.00 67.58  ? 278 PRO B N   1 
ATOM   3320  C CA  . PRO B 2 256 ? 144.796 124.965 145.547 1.00 67.58  ? 278 PRO B CA  1 
ATOM   3321  C C   . PRO B 2 256 ? 145.921 124.023 145.950 1.00 67.58  ? 278 PRO B C   1 
ATOM   3322  O O   . PRO B 2 256 ? 145.702 123.047 146.670 1.00 67.58  ? 278 PRO B O   1 
ATOM   3323  C CB  . PRO B 2 256 ? 144.082 125.552 146.772 1.00 67.58  ? 278 PRO B CB  1 
ATOM   3324  C CG  . PRO B 2 256 ? 142.618 125.474 146.451 1.00 67.58  ? 278 PRO B CG  1 
ATOM   3325  C CD  . PRO B 2 256 ? 142.458 124.267 145.586 1.00 67.58  ? 278 PRO B CD  1 
ATOM   3326  N N   . ARG B 2 257 ? 147.129 124.322 145.482 1.00 67.17  ? 279 ARG B N   1 
ATOM   3327  C CA  . ARG B 2 257 ? 148.283 123.480 145.762 1.00 67.17  ? 279 ARG B CA  1 
ATOM   3328  C C   . ARG B 2 257 ? 149.546 124.312 145.617 1.00 67.17  ? 279 ARG B C   1 
ATOM   3329  O O   . ARG B 2 257 ? 149.534 125.397 145.031 1.00 67.17  ? 279 ARG B O   1 
ATOM   3330  C CB  . ARG B 2 257 ? 148.327 122.263 144.832 1.00 67.17  ? 279 ARG B CB  1 
ATOM   3331  C CG  . ARG B 2 257 ? 148.418 122.621 143.359 1.00 67.17  ? 279 ARG B CG  1 
ATOM   3332  C CD  . ARG B 2 257 ? 148.270 121.393 142.479 1.00 67.17  ? 279 ARG B CD  1 
ATOM   3333  N NE  . ARG B 2 257 ? 146.956 120.774 142.618 1.00 67.17  ? 279 ARG B NE  1 
ATOM   3334  C CZ  . ARG B 2 257 ? 146.552 119.717 141.922 1.00 67.17  ? 279 ARG B CZ  1 
ATOM   3335  N NH1 . ARG B 2 257 ? 147.362 119.155 141.035 1.00 67.17  ? 279 ARG B NH1 1 
ATOM   3336  N NH2 . ARG B 2 257 ? 145.338 119.219 142.113 1.00 67.17  ? 279 ARG B NH2 1 
ATOM   3337  N N   . THR B 2 258 ? 150.642 123.785 146.163 1.00 62.35  ? 280 THR B N   1 
ATOM   3338  C CA  . THR B 2 258 ? 151.943 124.435 146.082 1.00 62.35  ? 280 THR B CA  1 
ATOM   3339  C C   . THR B 2 258 ? 152.964 123.601 145.319 1.00 62.35  ? 280 THR B C   1 
ATOM   3340  O O   . THR B 2 258 ? 154.163 123.899 145.382 1.00 62.35  ? 280 THR B O   1 
ATOM   3341  C CB  . THR B 2 258 ? 152.475 124.748 147.484 1.00 62.35  ? 280 THR B CB  1 
ATOM   3342  O OG1 . THR B 2 258 ? 152.650 123.528 148.214 1.00 62.35  ? 280 THR B OG1 1 
ATOM   3343  C CG2 . THR B 2 258 ? 151.505 125.647 148.234 1.00 62.35  ? 280 THR B CG2 1 
ATOM   3344  N N   . SER B 2 259 ? 152.526 122.567 144.603 1.00 59.11  ? 281 SER B N   1 
ATOM   3345  C CA  . SER B 2 259 ? 153.437 121.711 143.860 1.00 59.11  ? 281 SER B CA  1 
ATOM   3346  C C   . SER B 2 259 ? 152.686 121.054 142.713 1.00 59.11  ? 281 SER B C   1 
ATOM   3347  O O   . SER B 2 259 ? 151.483 120.794 142.807 1.00 59.11  ? 281 SER B O   1 
ATOM   3348  C CB  . SER B 2 259 ? 154.068 120.643 144.761 1.00 59.11  ? 281 SER B CB  1 
ATOM   3349  O OG  . SER B 2 259 ? 155.230 120.096 144.164 1.00 59.11  ? 281 SER B OG  1 
ATOM   3350  N N   . PHE B 2 260 ? 153.410 120.787 141.629 1.00 57.45  ? 282 PHE B N   1 
ATOM   3351  C CA  . PHE B 2 260 ? 152.838 120.142 140.457 1.00 57.45  ? 282 PHE B CA  1 
ATOM   3352  C C   . PHE B 2 260 ? 153.925 119.344 139.755 1.00 57.45  ? 282 PHE B C   1 
ATOM   3353  O O   . PHE B 2 260 ? 155.091 119.747 139.728 1.00 57.45  ? 282 PHE B O   1 
ATOM   3354  C CB  . PHE B 2 260 ? 152.219 121.163 139.496 1.00 57.45  ? 282 PHE B CB  1 
ATOM   3355  C CG  . PHE B 2 260 ? 151.578 120.547 138.286 1.00 57.45  ? 282 PHE B CG  1 
ATOM   3356  C CD1 . PHE B 2 260 ? 152.220 120.569 137.059 1.00 57.45  ? 282 PHE B CD1 1 
ATOM   3357  C CD2 . PHE B 2 260 ? 150.335 119.944 138.375 1.00 57.45  ? 282 PHE B CD2 1 
ATOM   3358  C CE1 . PHE B 2 260 ? 151.633 120.003 135.944 1.00 57.45  ? 282 PHE B CE1 1 
ATOM   3359  C CE2 . PHE B 2 260 ? 149.744 119.375 137.263 1.00 57.45  ? 282 PHE B CE2 1 
ATOM   3360  C CZ  . PHE B 2 260 ? 150.393 119.405 136.046 1.00 57.45  ? 282 PHE B CZ  1 
ATOM   3361  N N   . THR B 2 261 ? 153.533 118.206 139.187 1.00 61.25  ? 283 THR B N   1 
ATOM   3362  C CA  . THR B 2 261 ? 154.455 117.290 138.524 1.00 61.25  ? 283 THR B CA  1 
ATOM   3363  C C   . THR B 2 261 ? 154.159 117.292 137.029 1.00 61.25  ? 283 THR B C   1 
ATOM   3364  O O   . THR B 2 261 ? 153.136 116.753 136.592 1.00 61.25  ? 283 THR B O   1 
ATOM   3365  C CB  . THR B 2 261 ? 154.337 115.882 139.101 1.00 61.25  ? 283 THR B CB  1 
ATOM   3366  O OG1 . THR B 2 261 ? 154.662 115.906 140.496 1.00 61.25  ? 283 THR B OG1 1 
ATOM   3367  C CG2 . THR B 2 261 ? 155.282 114.932 138.382 1.00 61.25  ? 283 THR B CG2 1 
ATOM   3368  N N   . VAL B 2 262 ? 155.053 117.893 136.251 1.00 62.15  ? 284 VAL B N   1 
ATOM   3369  C CA  . VAL B 2 262 ? 154.915 117.917 134.799 1.00 62.15  ? 284 VAL B CA  1 
ATOM   3370  C C   . VAL B 2 262 ? 155.467 116.618 134.230 1.00 62.15  ? 284 VAL B C   1 
ATOM   3371  O O   . VAL B 2 262 ? 156.580 116.201 134.570 1.00 62.15  ? 284 VAL B O   1 
ATOM   3372  C CB  . VAL B 2 262 ? 155.637 119.136 134.204 1.00 62.15  ? 284 VAL B CB  1 
ATOM   3373  C CG1 . VAL B 2 262 ? 155.533 119.125 132.687 1.00 62.15  ? 284 VAL B CG1 1 
ATOM   3374  C CG2 . VAL B 2 262 ? 155.062 120.423 134.773 1.00 62.15  ? 284 VAL B CG2 1 
ATOM   3375  N N   . GLN B 2 263 ? 154.692 115.975 133.365 1.00 76.31  ? 285 GLN B N   1 
ATOM   3376  C CA  . GLN B 2 263 ? 155.066 114.706 132.759 1.00 76.31  ? 285 GLN B CA  1 
ATOM   3377  C C   . GLN B 2 263 ? 155.248 114.878 131.254 1.00 76.31  ? 285 GLN B C   1 
ATOM   3378  O O   . GLN B 2 263 ? 155.025 115.955 130.693 1.00 76.31  ? 285 GLN B O   1 
ATOM   3379  C CB  . GLN B 2 263 ? 154.020 113.634 133.069 1.00 76.31  ? 285 GLN B CB  1 
ATOM   3380  C CG  . GLN B 2 263 ? 153.923 113.272 134.541 1.00 76.31  ? 285 GLN B CG  1 
ATOM   3381  C CD  . GLN B 2 263 ? 152.947 112.142 134.799 1.00 76.31  ? 285 GLN B CD  1 
ATOM   3382  O OE1 . GLN B 2 263 ? 152.275 111.666 133.884 1.00 76.31  ? 285 GLN B OE1 1 
ATOM   3383  N NE2 . GLN B 2 263 ? 152.866 111.704 136.050 1.00 76.31  ? 285 GLN B NE2 1 
ATOM   3384  N N   . ASP B 2 264 ? 155.663 113.788 130.604 1.00 80.75  ? 286 ASP B N   1 
ATOM   3385  C CA  . ASP B 2 264 ? 155.885 113.743 129.159 1.00 80.75  ? 286 ASP B CA  1 
ATOM   3386  C C   . ASP B 2 264 ? 156.907 114.798 128.725 1.00 80.75  ? 286 ASP B C   1 
ATOM   3387  O O   . ASP B 2 264 ? 156.611 115.722 127.965 1.00 80.75  ? 286 ASP B O   1 
ATOM   3388  C CB  . ASP B 2 264 ? 154.565 113.901 128.396 1.00 80.75  ? 286 ASP B CB  1 
ATOM   3389  C CG  . ASP B 2 264 ? 154.666 113.436 126.956 1.00 80.75  ? 286 ASP B CG  1 
ATOM   3390  O OD1 . ASP B 2 264 ? 155.715 112.870 126.585 1.00 80.75  ? 286 ASP B OD1 1 
ATOM   3391  O OD2 . ASP B 2 264 ? 153.696 113.638 126.196 1.00 80.75  ? 286 ASP B OD2 1 
ATOM   3392  N N   . LEU B 2 265 ? 158.128 114.639 129.228 1.00 74.82  ? 287 LEU B N   1 
ATOM   3393  C CA  . LEU B 2 265 ? 159.233 115.526 128.906 1.00 74.82  ? 287 LEU B CA  1 
ATOM   3394  C C   . LEU B 2 265 ? 160.386 114.725 128.315 1.00 74.82  ? 287 LEU B C   1 
ATOM   3395  O O   . LEU B 2 265 ? 160.502 113.514 128.522 1.00 74.82  ? 287 LEU B O   1 
ATOM   3396  C CB  . LEU B 2 265 ? 159.710 116.297 130.143 1.00 74.82  ? 287 LEU B CB  1 
ATOM   3397  C CG  . LEU B 2 265 ? 158.664 117.178 130.829 1.00 74.82  ? 287 LEU B CG  1 
ATOM   3398  C CD1 . LEU B 2 265 ? 159.290 117.964 131.971 1.00 74.82  ? 287 LEU B CD1 1 
ATOM   3399  C CD2 . LEU B 2 265 ? 158.008 118.113 129.827 1.00 74.82  ? 287 LEU B CD2 1 
ATOM   3400  N N   . LYS B 2 266 ? 161.240 115.419 127.573 1.00 83.32  ? 288 LYS B N   1 
ATOM   3401  C CA  . LYS B 2 266 ? 162.372 114.769 126.924 1.00 83.32  ? 288 LYS B CA  1 
ATOM   3402  C C   . LYS B 2 266 ? 163.488 114.532 127.936 1.00 83.32  ? 288 LYS B C   1 
ATOM   3403  O O   . LYS B 2 266 ? 163.803 115.430 128.723 1.00 83.32  ? 288 LYS B O   1 
ATOM   3404  C CB  . LYS B 2 266 ? 162.886 115.619 125.766 1.00 83.32  ? 288 LYS B CB  1 
ATOM   3405  C CG  . LYS B 2 266 ? 163.778 114.869 124.791 1.00 83.32  ? 288 LYS B CG  1 
ATOM   3406  C CD  . LYS B 2 266 ? 164.148 115.736 123.601 1.00 83.32  ? 288 LYS B CD  1 
ATOM   3407  C CE  . LYS B 2 266 ? 164.862 114.926 122.533 1.00 83.32  ? 288 LYS B CE  1 
ATOM   3408  N NZ  . LYS B 2 266 ? 164.018 113.806 122.034 1.00 83.32  ? 288 LYS B NZ  1 
ATOM   3409  N N   . PRO B 2 267 ? 164.100 113.348 127.951 1.00 77.55  ? 289 PRO B N   1 
ATOM   3410  C CA  . PRO B 2 267 ? 165.176 113.090 128.915 1.00 77.55  ? 289 PRO B CA  1 
ATOM   3411  C C   . PRO B 2 267 ? 166.420 113.907 128.601 1.00 77.55  ? 289 PRO B C   1 
ATOM   3412  O O   . PRO B 2 267 ? 166.767 114.122 127.437 1.00 77.55  ? 289 PRO B O   1 
ATOM   3413  C CB  . PRO B 2 267 ? 165.443 111.587 128.760 1.00 77.55  ? 289 PRO B CB  1 
ATOM   3414  C CG  . PRO B 2 267 ? 164.236 111.040 128.058 1.00 77.55  ? 289 PRO B CG  1 
ATOM   3415  C CD  . PRO B 2 267 ? 163.751 112.145 127.179 1.00 77.55  ? 289 PRO B CD  1 
ATOM   3416  N N   . PHE B 2 268 ? 167.086 114.363 129.663 1.00 81.97  ? 290 PHE B N   1 
ATOM   3417  C CA  . PHE B 2 268 ? 168.341 115.112 129.565 1.00 81.97  ? 290 PHE B CA  1 
ATOM   3418  C C   . PHE B 2 268 ? 168.166 116.388 128.741 1.00 81.97  ? 290 PHE B C   1 
ATOM   3419  O O   . PHE B 2 268 ? 168.927 116.669 127.814 1.00 81.97  ? 290 PHE B O   1 
ATOM   3420  C CB  . PHE B 2 268 ? 169.460 114.236 128.995 1.00 81.97  ? 290 PHE B CB  1 
ATOM   3421  C CG  . PHE B 2 268 ? 170.839 114.745 129.298 1.00 81.97  ? 290 PHE B CG  1 
ATOM   3422  C CD1 . PHE B 2 268 ? 171.698 115.111 128.275 1.00 81.97  ? 290 PHE B CD1 1 
ATOM   3423  C CD2 . PHE B 2 268 ? 171.275 114.865 130.606 1.00 81.97  ? 290 PHE B CD2 1 
ATOM   3424  C CE1 . PHE B 2 268 ? 172.967 115.582 128.552 1.00 81.97  ? 290 PHE B CE1 1 
ATOM   3425  C CE2 . PHE B 2 268 ? 172.542 115.335 130.890 1.00 81.97  ? 290 PHE B CE2 1 
ATOM   3426  C CZ  . PHE B 2 268 ? 173.389 115.694 129.861 1.00 81.97  ? 290 PHE B CZ  1 
ATOM   3427  N N   . THR B 2 269 ? 167.145 117.168 129.092 1.00 79.33  ? 291 THR B N   1 
ATOM   3428  C CA  . THR B 2 269 ? 166.873 118.445 128.446 1.00 79.33  ? 291 THR B CA  1 
ATOM   3429  C C   . THR B 2 269 ? 166.487 119.470 129.501 1.00 79.33  ? 291 THR B C   1 
ATOM   3430  O O   . THR B 2 269 ? 165.775 119.149 130.457 1.00 79.33  ? 291 THR B O   1 
ATOM   3431  C CB  . THR B 2 269 ? 165.755 118.330 127.398 1.00 79.33  ? 291 THR B CB  1 
ATOM   3432  O OG1 . THR B 2 269 ? 164.586 117.760 128.001 1.00 79.33  ? 291 THR B OG1 1 
ATOM   3433  C CG2 . THR B 2 269 ? 166.193 117.467 126.222 1.00 79.33  ? 291 THR B CG2 1 
ATOM   3434  N N   . GLU B 2 270 ? 166.959 120.700 129.323 1.00 73.97  ? 292 GLU B N   1 
ATOM   3435  C CA  . GLU B 2 270 ? 166.685 121.780 130.258 1.00 73.97  ? 292 GLU B CA  1 
ATOM   3436  C C   . GLU B 2 270 ? 165.381 122.482 129.899 1.00 73.97  ? 292 GLU B C   1 
ATOM   3437  O O   . GLU B 2 270 ? 164.954 122.487 128.742 1.00 73.97  ? 292 GLU B O   1 
ATOM   3438  C CB  . GLU B 2 270 ? 167.835 122.788 130.270 1.00 73.97  ? 292 GLU B CB  1 
ATOM   3439  C CG  . GLU B 2 270 ? 168.025 123.500 131.600 1.00 73.97  ? 292 GLU B CG  1 
ATOM   3440  C CD  . GLU B 2 270 ? 169.133 124.535 131.556 1.00 73.97  ? 292 GLU B CD  1 
ATOM   3441  O OE1 . GLU B 2 270 ? 168.885 125.652 131.057 1.00 73.97  ? 292 GLU B OE1 1 
ATOM   3442  O OE2 . GLU B 2 270 ? 170.251 124.231 132.022 1.00 73.97  ? 292 GLU B OE2 1 
ATOM   3443  N N   . TYR B 2 271 ? 164.749 123.077 130.909 1.00 66.91  ? 293 TYR B N   1 
ATOM   3444  C CA  . TYR B 2 271 ? 163.483 123.771 130.724 1.00 66.91  ? 293 TYR B CA  1 
ATOM   3445  C C   . TYR B 2 271 ? 163.455 125.028 131.582 1.00 66.91  ? 293 TYR B C   1 
ATOM   3446  O O   . TYR B 2 271 ? 164.223 125.175 132.535 1.00 66.91  ? 293 TYR B O   1 
ATOM   3447  C CB  . TYR B 2 271 ? 162.289 122.873 131.073 1.00 66.91  ? 293 TYR B CB  1 
ATOM   3448  C CG  . TYR B 2 271 ? 162.077 121.729 130.109 1.00 66.91  ? 293 TYR B CG  1 
ATOM   3449  C CD1 . TYR B 2 271 ? 161.283 121.885 128.980 1.00 66.91  ? 293 TYR B CD1 1 
ATOM   3450  C CD2 . TYR B 2 271 ? 162.665 120.492 130.329 1.00 66.91  ? 293 TYR B CD2 1 
ATOM   3451  C CE1 . TYR B 2 271 ? 161.085 120.841 128.096 1.00 66.91  ? 293 TYR B CE1 1 
ATOM   3452  C CE2 . TYR B 2 271 ? 162.471 119.444 129.453 1.00 66.91  ? 293 TYR B CE2 1 
ATOM   3453  C CZ  . TYR B 2 271 ? 161.682 119.623 128.338 1.00 66.91  ? 293 TYR B CZ  1 
ATOM   3454  O OH  . TYR B 2 271 ? 161.488 118.581 127.462 1.00 66.91  ? 293 TYR B OH  1 
ATOM   3455  N N   . VAL B 2 272 ? 162.551 125.938 131.224 1.00 64.80  ? 294 VAL B N   1 
ATOM   3456  C CA  . VAL B 2 272 ? 162.326 127.179 131.953 1.00 64.80  ? 294 VAL B CA  1 
ATOM   3457  C C   . VAL B 2 272 ? 160.850 127.255 132.315 1.00 64.80  ? 294 VAL B C   1 
ATOM   3458  O O   . VAL B 2 272 ? 159.986 126.904 131.505 1.00 64.80  ? 294 VAL B O   1 
ATOM   3459  C CB  . VAL B 2 272 ? 162.753 128.413 131.129 1.00 64.80  ? 294 VAL B CB  1 
ATOM   3460  C CG1 . VAL B 2 272 ? 162.621 129.681 131.956 1.00 64.80  ? 294 VAL B CG1 1 
ATOM   3461  C CG2 . VAL B 2 272 ? 164.177 128.249 130.623 1.00 64.80  ? 294 VAL B CG2 1 
ATOM   3462  N N   . PHE B 2 273 ? 160.561 127.714 133.532 1.00 57.53  ? 295 PHE B N   1 
ATOM   3463  C CA  . PHE B 2 273 ? 159.202 127.734 134.048 1.00 57.53  ? 295 PHE B CA  1 
ATOM   3464  C C   . PHE B 2 273 ? 158.839 129.127 134.544 1.00 57.53  ? 295 PHE B C   1 
ATOM   3465  O O   . PHE B 2 273 ? 159.706 129.919 134.921 1.00 57.53  ? 295 PHE B O   1 
ATOM   3466  C CB  . PHE B 2 273 ? 159.022 126.718 135.185 1.00 57.53  ? 295 PHE B CB  1 
ATOM   3467  C CG  . PHE B 2 273 ? 159.092 125.286 134.736 1.00 57.53  ? 295 PHE B CG  1 
ATOM   3468  C CD1 . PHE B 2 273 ? 157.935 124.558 134.519 1.00 57.53  ? 295 PHE B CD1 1 
ATOM   3469  C CD2 . PHE B 2 273 ? 160.314 124.669 134.533 1.00 57.53  ? 295 PHE B CD2 1 
ATOM   3470  C CE1 . PHE B 2 273 ? 157.997 123.240 134.107 1.00 57.53  ? 295 PHE B CE1 1 
ATOM   3471  C CE2 . PHE B 2 273 ? 160.381 123.352 134.121 1.00 57.53  ? 295 PHE B CE2 1 
ATOM   3472  C CZ  . PHE B 2 273 ? 159.221 122.638 133.908 1.00 57.53  ? 295 PHE B CZ  1 
ATOM   3473  N N   . ARG B 2 274 ? 157.538 129.412 134.535 1.00 59.59  ? 296 ARG B N   1 
ATOM   3474  C CA  . ARG B 2 274 ? 156.991 130.646 135.078 1.00 59.59  ? 296 ARG B CA  1 
ATOM   3475  C C   . ARG B 2 274 ? 155.543 130.391 135.470 1.00 59.59  ? 296 ARG B C   1 
ATOM   3476  O O   . ARG B 2 274 ? 154.869 129.547 134.874 1.00 59.59  ? 296 ARG B O   1 
ATOM   3477  C CB  . ARG B 2 274 ? 157.086 131.803 134.077 1.00 59.59  ? 296 ARG B CB  1 
ATOM   3478  C CG  . ARG B 2 274 ? 156.364 131.553 132.766 1.00 59.59  ? 296 ARG B CG  1 
ATOM   3479  C CD  . ARG B 2 274 ? 156.432 132.771 131.861 1.00 59.59  ? 296 ARG B CD  1 
ATOM   3480  N NE  . ARG B 2 274 ? 155.720 132.558 130.605 1.00 59.59  ? 296 ARG B NE  1 
ATOM   3481  C CZ  . ARG B 2 274 ? 155.593 133.477 129.654 1.00 59.59  ? 296 ARG B CZ  1 
ATOM   3482  N NH1 . ARG B 2 274 ? 156.133 134.677 129.813 1.00 59.59  ? 296 ARG B NH1 1 
ATOM   3483  N NH2 . ARG B 2 274 ? 154.928 133.195 128.542 1.00 59.59  ? 296 ARG B NH2 1 
ATOM   3484  N N   . ILE B 2 275 ? 155.068 131.123 136.480 1.00 61.26  ? 297 ILE B N   1 
ATOM   3485  C CA  . ILE B 2 275 ? 153.760 130.866 137.066 1.00 61.26  ? 297 ILE B CA  1 
ATOM   3486  C C   . ILE B 2 275 ? 153.102 132.186 137.451 1.00 61.26  ? 297 ILE B C   1 
ATOM   3487  O O   . ILE B 2 275 ? 153.765 133.203 137.663 1.00 61.26  ? 297 ILE B O   1 
ATOM   3488  C CB  . ILE B 2 275 ? 153.867 129.930 138.296 1.00 61.26  ? 297 ILE B CB  1 
ATOM   3489  C CG1 . ILE B 2 275 ? 152.509 129.328 138.656 1.00 61.26  ? 297 ILE B CG1 1 
ATOM   3490  C CG2 . ILE B 2 275 ? 154.435 130.674 139.493 1.00 61.26  ? 297 ILE B CG2 1 
ATOM   3491  C CD1 . ILE B 2 275 ? 152.609 128.170 139.623 1.00 61.26  ? 297 ILE B CD1 1 
ATOM   3492  N N   . ARG B 2 276 ? 151.771 132.157 137.527 1.00 60.60  ? 298 ARG B N   1 
ATOM   3493  C CA  . ARG B 2 276 ? 150.980 133.289 137.983 1.00 60.60  ? 298 ARG B CA  1 
ATOM   3494  C C   . ARG B 2 276 ? 149.701 132.757 138.612 1.00 60.60  ? 298 ARG B C   1 
ATOM   3495  O O   . ARG B 2 276 ? 149.177 131.719 138.198 1.00 60.60  ? 298 ARG B O   1 
ATOM   3496  C CB  . ARG B 2 276 ? 150.660 134.260 136.840 1.00 60.60  ? 298 ARG B CB  1 
ATOM   3497  C CG  . ARG B 2 276 ? 149.863 133.648 135.701 1.00 60.60  ? 298 ARG B CG  1 
ATOM   3498  C CD  . ARG B 2 276 ? 149.524 134.692 134.650 1.00 60.60  ? 298 ARG B CD  1 
ATOM   3499  N NE  . ARG B 2 276 ? 148.683 134.149 133.588 1.00 60.60  ? 298 ARG B NE  1 
ATOM   3500  C CZ  . ARG B 2 276 ? 148.199 134.866 132.579 1.00 60.60  ? 298 ARG B CZ  1 
ATOM   3501  N NH1 . ARG B 2 276 ? 148.473 136.161 132.493 1.00 60.60  ? 298 ARG B NH1 1 
ATOM   3502  N NH2 . ARG B 2 276 ? 147.441 134.290 131.657 1.00 60.60  ? 298 ARG B NH2 1 
ATOM   3503  N N   . SER B 2 277 ? 149.201 133.474 139.614 1.00 61.30  ? 299 SER B N   1 
ATOM   3504  C CA  . SER B 2 277 ? 148.105 132.991 140.439 1.00 61.30  ? 299 SER B CA  1 
ATOM   3505  C C   . SER B 2 277 ? 146.887 133.897 140.319 1.00 61.30  ? 299 SER B C   1 
ATOM   3506  O O   . SER B 2 277 ? 146.987 135.074 139.964 1.00 61.30  ? 299 SER B O   1 
ATOM   3507  C CB  . SER B 2 277 ? 148.527 132.887 141.910 1.00 61.30  ? 299 SER B CB  1 
ATOM   3508  O OG  . SER B 2 277 ? 148.796 134.167 142.454 1.00 61.30  ? 299 SER B OG  1 
ATOM   3509  N N   . ILE B 2 278 ? 145.724 133.318 140.627 1.00 57.20  ? 300 ILE B N   1 
ATOM   3510  C CA  . ILE B 2 278 ? 144.453 134.033 140.635 1.00 57.20  ? 300 ILE B CA  1 
ATOM   3511  C C   . ILE B 2 278 ? 143.520 133.302 141.593 1.00 57.20  ? 300 ILE B C   1 
ATOM   3512  O O   . ILE B 2 278 ? 143.752 132.146 141.954 1.00 57.20  ? 300 ILE B O   1 
ATOM   3513  C CB  . ILE B 2 278 ? 143.832 134.133 139.219 1.00 57.20  ? 300 ILE B CB  1 
ATOM   3514  C CG1 . ILE B 2 278 ? 142.770 135.233 139.163 1.00 57.20  ? 300 ILE B CG1 1 
ATOM   3515  C CG2 . ILE B 2 278 ? 143.236 132.801 138.803 1.00 57.20  ? 300 ILE B CG2 1 
ATOM   3516  C CD1 . ILE B 2 278 ? 142.339 135.592 137.761 1.00 57.20  ? 300 ILE B CD1 1 
ATOM   3517  N N   . LYS B 2 279 ? 142.461 133.990 142.014 1.00 58.42  ? 301 LYS B N   1 
ATOM   3518  C CA  . LYS B 2 279 ? 141.518 133.413 142.963 1.00 58.42  ? 301 LYS B CA  1 
ATOM   3519  C C   . LYS B 2 279 ? 140.842 132.177 142.376 1.00 58.42  ? 301 LYS B C   1 
ATOM   3520  O O   . LYS B 2 279 ? 140.717 132.026 141.158 1.00 58.42  ? 301 LYS B O   1 
ATOM   3521  C CB  . LYS B 2 279 ? 140.468 134.450 143.362 1.00 58.42  ? 301 LYS B CB  1 
ATOM   3522  C CG  . LYS B 2 279 ? 139.745 134.140 144.662 1.00 58.42  ? 301 LYS B CG  1 
ATOM   3523  C CD  . LYS B 2 279 ? 138.795 135.261 145.043 1.00 58.42  ? 301 LYS B CD  1 
ATOM   3524  C CE  . LYS B 2 279 ? 138.041 134.934 146.319 1.00 58.42  ? 301 LYS B CE  1 
ATOM   3525  N NZ  . LYS B 2 279 ? 137.203 133.713 146.167 1.00 58.42  ? 301 LYS B NZ  1 
ATOM   3526  N N   . ASP B 2 280 ? 140.405 131.281 143.267 1.00 61.27  ? 302 ASP B N   1 
ATOM   3527  C CA  . ASP B 2 280 ? 139.807 130.022 142.833 1.00 61.27  ? 302 ASP B CA  1 
ATOM   3528  C C   . ASP B 2 280 ? 138.495 130.250 142.092 1.00 61.27  ? 302 ASP B C   1 
ATOM   3529  O O   . ASP B 2 280 ? 138.203 129.559 141.109 1.00 61.27  ? 302 ASP B O   1 
ATOM   3530  C CB  . ASP B 2 280 ? 139.586 129.106 144.037 1.00 61.27  ? 302 ASP B CB  1 
ATOM   3531  C CG  . ASP B 2 280 ? 139.520 127.640 143.653 1.00 61.27  ? 302 ASP B CG  1 
ATOM   3532  O OD1 . ASP B 2 280 ? 139.325 127.339 142.457 1.00 61.27  ? 302 ASP B OD1 1 
ATOM   3533  O OD2 . ASP B 2 280 ? 139.661 126.785 144.552 1.00 61.27  ? 302 ASP B OD2 1 
ATOM   3534  N N   . SER B 2 281 ? 137.692 131.213 142.543 1.00 62.24  ? 303 SER B N   1 
ATOM   3535  C CA  . SER B 2 281 ? 136.385 131.456 141.944 1.00 62.24  ? 303 SER B CA  1 
ATOM   3536  C C   . SER B 2 281 ? 136.465 132.065 140.551 1.00 62.24  ? 303 SER B C   1 
ATOM   3537  O O   . SER B 2 281 ? 135.417 132.375 139.975 1.00 62.24  ? 303 SER B O   1 
ATOM   3538  C CB  . SER B 2 281 ? 135.555 132.363 142.855 1.00 62.24  ? 303 SER B CB  1 
ATOM   3539  O OG  . SER B 2 281 ? 135.473 131.833 144.167 1.00 62.24  ? 303 SER B OG  1 
ATOM   3540  N N   . GLY B 2 282 ? 137.662 132.243 139.996 1.00 57.61  ? 304 GLY B N   1 
ATOM   3541  C CA  . GLY B 2 282 ? 137.814 132.834 138.685 1.00 57.61  ? 304 GLY B CA  1 
ATOM   3542  C C   . GLY B 2 282 ? 137.663 134.337 138.636 1.00 57.61  ? 304 GLY B C   1 
ATOM   3543  O O   . GLY B 2 282 ? 137.842 134.924 137.561 1.00 57.61  ? 304 GLY B O   1 
ATOM   3544  N N   . LYS B 2 283 ? 137.342 134.979 139.755 1.00 57.70  ? 305 LYS B N   1 
ATOM   3545  C CA  . LYS B 2 283 ? 137.195 136.422 139.803 1.00 57.70  ? 305 LYS B CA  1 
ATOM   3546  C C   . LYS B 2 283 ? 138.542 137.073 140.111 1.00 57.70  ? 305 LYS B C   1 
ATOM   3547  O O   . LYS B 2 283 ? 139.561 136.402 140.294 1.00 57.70  ? 305 LYS B O   1 
ATOM   3548  C CB  . LYS B 2 283 ? 136.138 136.812 140.834 1.00 57.70  ? 305 LYS B CB  1 
ATOM   3549  C CG  . LYS B 2 283 ? 134.790 136.149 140.610 1.00 57.70  ? 305 LYS B CG  1 
ATOM   3550  C CD  . LYS B 2 283 ? 133.801 136.515 141.702 1.00 57.70  ? 305 LYS B CD  1 
ATOM   3551  C CE  . LYS B 2 283 ? 132.453 135.853 141.469 1.00 57.70  ? 305 LYS B CE  1 
ATOM   3552  N NZ  . LYS B 2 283 ? 131.472 136.201 142.533 1.00 57.70  ? 305 LYS B NZ  1 
ATOM   3553  N N   . GLY B 2 284 ? 138.550 138.401 140.168 1.00 49.79  ? 306 GLY B N   1 
ATOM   3554  C CA  . GLY B 2 284 ? 139.778 139.130 140.412 1.00 49.79  ? 306 GLY B CA  1 
ATOM   3555  C C   . GLY B 2 284 ? 140.563 139.397 139.145 1.00 49.79  ? 306 GLY B C   1 
ATOM   3556  O O   . GLY B 2 284 ? 139.983 139.526 138.063 1.00 49.79  ? 306 GLY B O   1 
ATOM   3557  N N   . TYR B 2 285 ? 141.885 139.483 139.265 1.00 51.46  ? 307 TYR B N   1 
ATOM   3558  C CA  . TYR B 2 285 ? 142.747 139.762 138.128 1.00 51.46  ? 307 TYR B CA  1 
ATOM   3559  C C   . TYR B 2 285 ? 143.969 138.857 138.184 1.00 51.46  ? 307 TYR B C   1 
ATOM   3560  O O   . TYR B 2 285 ? 144.473 138.535 139.262 1.00 51.46  ? 307 TYR B O   1 
ATOM   3561  C CB  . TYR B 2 285 ? 143.180 141.233 138.098 1.00 51.46  ? 307 TYR B CB  1 
ATOM   3562  C CG  . TYR B 2 285 ? 142.028 142.210 138.160 1.00 51.46  ? 307 TYR B CG  1 
ATOM   3563  C CD1 . TYR B 2 285 ? 141.273 142.495 137.031 1.00 51.46  ? 307 TYR B CD1 1 
ATOM   3564  C CD2 . TYR B 2 285 ? 141.694 142.846 139.348 1.00 51.46  ? 307 TYR B CD2 1 
ATOM   3565  C CE1 . TYR B 2 285 ? 140.219 143.387 137.083 1.00 51.46  ? 307 TYR B CE1 1 
ATOM   3566  C CE2 . TYR B 2 285 ? 140.642 143.739 139.409 1.00 51.46  ? 307 TYR B CE2 1 
ATOM   3567  C CZ  . TYR B 2 285 ? 139.908 144.005 138.274 1.00 51.46  ? 307 TYR B CZ  1 
ATOM   3568  O OH  . TYR B 2 285 ? 138.859 144.893 138.328 1.00 51.46  ? 307 TYR B OH  1 
ATOM   3569  N N   . TRP B 2 286 ? 144.437 138.450 137.007 1.00 53.02  ? 308 TRP B N   1 
ATOM   3570  C CA  . TRP B 2 286 ? 145.608 137.589 136.923 1.00 53.02  ? 308 TRP B CA  1 
ATOM   3571  C C   . TRP B 2 286 ? 146.860 138.347 137.348 1.00 53.02  ? 308 TRP B C   1 
ATOM   3572  O O   . TRP B 2 286 ? 147.075 139.496 136.953 1.00 53.02  ? 308 TRP B O   1 
ATOM   3573  C CB  . TRP B 2 286 ? 145.778 137.056 135.502 1.00 53.02  ? 308 TRP B CB  1 
ATOM   3574  C CG  . TRP B 2 286 ? 144.804 135.978 135.139 1.00 53.02  ? 308 TRP B CG  1 
ATOM   3575  C CD1 . TRP B 2 286 ? 143.599 136.138 134.520 1.00 53.02  ? 308 TRP B CD1 1 
ATOM   3576  C CD2 . TRP B 2 286 ? 144.953 134.573 135.371 1.00 53.02  ? 308 TRP B CD2 1 
ATOM   3577  N NE1 . TRP B 2 286 ? 142.988 134.919 134.352 1.00 53.02  ? 308 TRP B NE1 1 
ATOM   3578  C CE2 . TRP B 2 286 ? 143.799 133.942 134.867 1.00 53.02  ? 308 TRP B CE2 1 
ATOM   3579  C CE3 . TRP B 2 286 ? 145.950 133.787 135.956 1.00 53.02  ? 308 TRP B CE3 1 
ATOM   3580  C CZ2 . TRP B 2 286 ? 143.614 132.563 134.930 1.00 53.02  ? 308 TRP B CZ2 1 
ATOM   3581  C CZ3 . TRP B 2 286 ? 145.764 132.418 136.018 1.00 53.02  ? 308 TRP B CZ3 1 
ATOM   3582  C CH2 . TRP B 2 286 ? 144.606 131.821 135.508 1.00 53.02  ? 308 TRP B CH2 1 
ATOM   3583  N N   . SER B 2 287 ? 147.688 137.693 138.157 1.00 57.32  ? 309 SER B N   1 
ATOM   3584  C CA  . SER B 2 287 ? 148.917 138.301 138.635 1.00 57.32  ? 309 SER B CA  1 
ATOM   3585  C C   . SER B 2 287 ? 149.969 138.328 137.529 1.00 57.32  ? 309 SER B C   1 
ATOM   3586  O O   . SER B 2 287 ? 149.816 137.720 136.466 1.00 57.32  ? 309 SER B O   1 
ATOM   3587  C CB  . SER B 2 287 ? 149.447 137.546 139.852 1.00 57.32  ? 309 SER B CB  1 
ATOM   3588  O OG  . SER B 2 287 ? 150.643 138.134 140.332 1.00 57.32  ? 309 SER B OG  1 
ATOM   3589  N N   . ASP B 2 288 ? 151.054 139.052 137.793 1.00 69.04  ? 310 ASP B N   1 
ATOM   3590  C CA  . ASP B 2 288 ? 152.153 139.130 136.845 1.00 69.04  ? 310 ASP B CA  1 
ATOM   3591  C C   . ASP B 2 288 ? 152.934 137.817 136.827 1.00 69.04  ? 310 ASP B C   1 
ATOM   3592  O O   . ASP B 2 288 ? 152.797 136.963 137.708 1.00 69.04  ? 310 ASP B O   1 
ATOM   3593  C CB  . ASP B 2 288 ? 153.079 140.294 137.192 1.00 69.04  ? 310 ASP B CB  1 
ATOM   3594  C CG  . ASP B 2 288 ? 152.363 141.629 137.190 1.00 69.04  ? 310 ASP B CG  1 
ATOM   3595  O OD1 . ASP B 2 288 ? 151.428 141.801 136.380 1.00 69.04  ? 310 ASP B OD1 1 
ATOM   3596  O OD2 . ASP B 2 288 ? 152.734 142.505 137.998 1.00 69.04  ? 310 ASP B OD2 1 
ATOM   3597  N N   . TRP B 2 289 ? 153.768 137.663 135.802 1.00 62.05  ? 311 TRP B N   1 
ATOM   3598  C CA  . TRP B 2 289 ? 154.571 136.456 135.673 1.00 62.05  ? 311 TRP B CA  1 
ATOM   3599  C C   . TRP B 2 289 ? 155.682 136.440 136.715 1.00 62.05  ? 311 TRP B C   1 
ATOM   3600  O O   . TRP B 2 289 ? 156.280 137.473 137.027 1.00 62.05  ? 311 TRP B O   1 
ATOM   3601  C CB  . TRP B 2 289 ? 155.163 136.357 134.268 1.00 62.05  ? 311 TRP B CB  1 
ATOM   3602  C CG  . TRP B 2 289 ? 154.141 136.086 133.209 1.00 62.05  ? 311 TRP B CG  1 
ATOM   3603  C CD1 . TRP B 2 289 ? 153.741 136.937 132.221 1.00 62.05  ? 311 TRP B CD1 1 
ATOM   3604  C CD2 . TRP B 2 289 ? 153.384 134.883 133.034 1.00 62.05  ? 311 TRP B CD2 1 
ATOM   3605  N NE1 . TRP B 2 289 ? 152.783 136.337 131.440 1.00 62.05  ? 311 TRP B NE1 1 
ATOM   3606  C CE2 . TRP B 2 289 ? 152.547 135.076 131.918 1.00 62.05  ? 311 TRP B CE2 1 
ATOM   3607  C CE3 . TRP B 2 289 ? 153.335 133.661 133.711 1.00 62.05  ? 311 TRP B CE3 1 
ATOM   3608  C CZ2 . TRP B 2 289 ? 151.670 134.094 131.465 1.00 62.05  ? 311 TRP B CZ2 1 
ATOM   3609  C CZ3 . TRP B 2 289 ? 152.464 132.688 133.259 1.00 62.05  ? 311 TRP B CZ3 1 
ATOM   3610  C CH2 . TRP B 2 289 ? 151.643 132.909 132.147 1.00 62.05  ? 311 TRP B CH2 1 
ATOM   3611  N N   . SER B 2 290 ? 155.952 135.256 137.256 1.00 64.59  ? 312 SER B N   1 
ATOM   3612  C CA  . SER B 2 290 ? 156.969 135.092 138.281 1.00 64.59  ? 312 SER B CA  1 
ATOM   3613  C C   . SER B 2 290 ? 158.362 135.113 137.657 1.00 64.59  ? 312 SER B C   1 
ATOM   3614  O O   . SER B 2 290 ? 158.532 135.258 136.443 1.00 64.59  ? 312 SER B O   1 
ATOM   3615  C CB  . SER B 2 290 ? 156.739 133.793 139.048 1.00 64.59  ? 312 SER B CB  1 
ATOM   3616  O OG  . SER B 2 290 ? 156.471 132.725 138.157 1.00 64.59  ? 312 SER B OG  1 
ATOM   3617  N N   . GLU B 2 291 ? 159.378 134.967 138.503 1.00 74.87  ? 313 GLU B N   1 
ATOM   3618  C CA  . GLU B 2 291 ? 160.746 134.887 138.016 1.00 74.87  ? 313 GLU B CA  1 
ATOM   3619  C C   . GLU B 2 291 ? 160.996 133.532 137.368 1.00 74.87  ? 313 GLU B C   1 
ATOM   3620  O O   . GLU B 2 291 ? 160.565 132.493 137.876 1.00 74.87  ? 313 GLU B O   1 
ATOM   3621  C CB  . GLU B 2 291 ? 161.733 135.118 139.159 1.00 74.87  ? 313 GLU B CB  1 
ATOM   3622  C CG  . GLU B 2 291 ? 161.644 136.499 139.792 1.00 74.87  ? 313 GLU B CG  1 
ATOM   3623  C CD  . GLU B 2 291 ? 162.090 137.606 138.854 1.00 74.87  ? 313 GLU B CD  1 
ATOM   3624  O OE1 . GLU B 2 291 ? 161.272 138.053 138.023 1.00 74.87  ? 313 GLU B OE1 1 
ATOM   3625  O OE2 . GLU B 2 291 ? 163.261 138.029 138.948 1.00 74.87  ? 313 GLU B OE2 1 
ATOM   3626  N N   . GLU B 2 292 ? 161.697 133.547 136.238 1.00 77.24  ? 314 GLU B N   1 
ATOM   3627  C CA  . GLU B 2 292 ? 161.957 132.323 135.492 1.00 77.24  ? 314 GLU B CA  1 
ATOM   3628  C C   . GLU B 2 292 ? 162.926 131.434 136.263 1.00 77.24  ? 314 GLU B C   1 
ATOM   3629  O O   . GLU B 2 292 ? 164.034 131.860 136.606 1.00 77.24  ? 314 GLU B O   1 
ATOM   3630  C CB  . GLU B 2 292 ? 162.514 132.656 134.111 1.00 77.24  ? 314 GLU B CB  1 
ATOM   3631  C CG  . GLU B 2 292 ? 161.549 133.424 133.224 1.00 77.24  ? 314 GLU B CG  1 
ATOM   3632  C CD  . GLU B 2 292 ? 162.061 133.579 131.806 1.00 77.24  ? 314 GLU B CD  1 
ATOM   3633  O OE1 . GLU B 2 292 ? 163.165 133.076 131.513 1.00 77.24  ? 314 GLU B OE1 1 
ATOM   3634  O OE2 . GLU B 2 292 ? 161.358 134.204 130.984 1.00 77.24  ? 314 GLU B OE2 1 
ATOM   3635  N N   . ALA B 2 293 ? 162.509 130.201 136.534 1.00 66.27  ? 315 ALA B N   1 
ATOM   3636  C CA  . ALA B 2 293 ? 163.332 129.218 137.221 1.00 66.27  ? 315 ALA B CA  1 
ATOM   3637  C C   . ALA B 2 293 ? 163.756 128.131 136.244 1.00 66.27  ? 315 ALA B C   1 
ATOM   3638  O O   . ALA B 2 293 ? 162.953 127.669 135.427 1.00 66.27  ? 315 ALA B O   1 
ATOM   3639  C CB  . ALA B 2 293 ? 162.581 128.597 138.401 1.00 66.27  ? 315 ALA B CB  1 
ATOM   3640  N N   . SER B 2 294 ? 165.019 127.725 136.331 1.00 66.82  ? 316 SER B N   1 
ATOM   3641  C CA  . SER B 2 294 ? 165.583 126.729 135.434 1.00 66.82  ? 316 SER B CA  1 
ATOM   3642  C C   . SER B 2 294 ? 165.587 125.355 136.093 1.00 66.82  ? 316 SER B C   1 
ATOM   3643  O O   . SER B 2 294 ? 165.620 125.232 137.319 1.00 66.82  ? 316 SER B O   1 
ATOM   3644  C CB  . SER B 2 294 ? 167.007 127.112 135.023 1.00 66.82  ? 316 SER B CB  1 
ATOM   3645  O OG  . SER B 2 294 ? 167.411 126.402 133.865 1.00 66.82  ? 316 SER B OG  1 
ATOM   3646  N N   . GLY B 2 295 ? 165.551 124.320 135.258 1.00 65.88  ? 317 GLY B N   1 
ATOM   3647  C CA  . GLY B 2 295 ? 165.566 122.952 135.737 1.00 65.88  ? 317 GLY B CA  1 
ATOM   3648  C C   . GLY B 2 295 ? 165.971 121.961 134.666 1.00 65.88  ? 317 GLY B C   1 
ATOM   3649  O O   . GLY B 2 295 ? 165.469 122.018 133.539 1.00 65.88  ? 317 GLY B O   1 
ATOM   3650  N N   . THR B 2 296 ? 166.878 121.050 135.002 1.00 67.71  ? 318 THR B N   1 
ATOM   3651  C CA  . THR B 2 296 ? 167.387 120.057 134.066 1.00 67.71  ? 318 THR B CA  1 
ATOM   3652  C C   . THR B 2 296 ? 166.851 118.682 134.441 1.00 67.71  ? 318 THR B C   1 
ATOM   3653  O O   . THR B 2 296 ? 166.916 118.283 135.608 1.00 67.71  ? 318 THR B O   1 
ATOM   3654  C CB  . THR B 2 296 ? 168.918 120.043 134.060 1.00 67.71  ? 318 THR B CB  1 
ATOM   3655  O OG1 . THR B 2 296 ? 169.409 121.358 133.770 1.00 67.71  ? 318 THR B OG1 1 
ATOM   3656  C CG2 . THR B 2 296 ? 169.440 119.072 133.011 1.00 67.71  ? 318 THR B CG2 1 
ATOM   3657  N N   . THR B 2 297 ? 166.323 117.966 133.452 1.00 70.68  ? 319 THR B N   1 
ATOM   3658  C CA  . THR B 2 297 ? 165.799 116.631 133.691 1.00 70.68  ? 319 THR B CA  1 
ATOM   3659  C C   . THR B 2 297 ? 166.930 115.654 133.998 1.00 70.68  ? 319 THR B C   1 
ATOM   3660  O O   . THR B 2 297 ? 168.091 115.866 133.636 1.00 70.68  ? 319 THR B O   1 
ATOM   3661  C CB  . THR B 2 297 ? 165.002 116.139 132.482 1.00 70.68  ? 319 THR B CB  1 
ATOM   3662  O OG1 . THR B 2 297 ? 165.837 116.156 131.318 1.00 70.68  ? 319 THR B OG1 1 
ATOM   3663  C CG2 . THR B 2 297 ? 163.794 117.027 132.243 1.00 70.68  ? 319 THR B CG2 1 
ATOM   3664  N N   . TYR B 2 298 ? 166.575 114.568 134.678 1.00 80.48  ? 320 TYR B N   1 
ATOM   3665  C CA  . TYR B 2 298 ? 167.539 113.535 135.014 1.00 80.48  ? 320 TYR B CA  1 
ATOM   3666  C C   . TYR B 2 298 ? 167.871 112.694 133.784 1.00 80.48  ? 320 TYR B C   1 
ATOM   3667  O O   . TYR B 2 298 ? 167.098 112.612 132.826 1.00 80.48  ? 320 TYR B O   1 
ATOM   3668  C CB  . TYR B 2 298 ? 167.003 112.645 136.136 1.00 80.48  ? 320 TYR B CB  1 
ATOM   3669  C CG  . TYR B 2 298 ? 168.057 111.803 136.817 1.00 80.48  ? 320 TYR B CG  1 
ATOM   3670  C CD1 . TYR B 2 298 ? 168.170 110.445 136.549 1.00 80.48  ? 320 TYR B CD1 1 
ATOM   3671  C CD2 . TYR B 2 298 ? 168.940 112.364 137.731 1.00 80.48  ? 320 TYR B CD2 1 
ATOM   3672  C CE1 . TYR B 2 298 ? 169.131 109.671 137.169 1.00 80.48  ? 320 TYR B CE1 1 
ATOM   3673  C CE2 . TYR B 2 298 ? 169.905 111.598 138.356 1.00 80.48  ? 320 TYR B CE2 1 
ATOM   3674  C CZ  . TYR B 2 298 ? 169.996 110.252 138.071 1.00 80.48  ? 320 TYR B CZ  1 
ATOM   3675  O OH  . TYR B 2 298 ? 170.954 109.484 138.690 1.00 80.48  ? 320 TYR B OH  1 
ATOM   3676  N N   . GLU B 2 299 ? 169.043 112.066 133.822 1.00 85.09  ? 321 GLU B N   1 
ATOM   3677  C CA  . GLU B 2 299 ? 169.486 111.242 132.710 1.00 85.09  ? 321 GLU B CA  1 
ATOM   3678  C C   . GLU B 2 299 ? 168.674 109.950 132.644 1.00 85.09  ? 321 GLU B C   1 
ATOM   3679  O O   . GLU B 2 299 ? 167.886 109.625 133.536 1.00 85.09  ? 321 GLU B O   1 
ATOM   3680  C CB  . GLU B 2 299 ? 170.976 110.927 132.836 1.00 85.09  ? 321 GLU B CB  1 
ATOM   3681  C CG  . GLU B 2 299 ? 171.869 112.155 132.864 1.00 85.09  ? 321 GLU B CG  1 
ATOM   3682  C CD  . GLU B 2 299 ? 173.342 111.805 132.807 1.00 85.09  ? 321 GLU B CD  1 
ATOM   3683  O OE1 . GLU B 2 299 ? 173.663 110.608 132.653 1.00 85.09  ? 321 GLU B OE1 1 
ATOM   3684  O OE2 . GLU B 2 299 ? 174.179 112.726 132.916 1.00 85.09  ? 321 GLU B OE2 1 
ATOM   3685  N N   . ASP B 2 300 ? 168.879 109.205 131.561 1.00 86.33  ? 322 ASP B N   1 
ATOM   3686  C CA  . ASP B 2 300 ? 168.182 107.945 131.355 1.00 86.33  ? 322 ASP B CA  1 
ATOM   3687  C C   . ASP B 2 300 ? 169.040 107.045 130.478 1.00 86.33  ? 322 ASP B C   1 
ATOM   3688  O O   . ASP B 2 300 ? 170.044 107.473 129.903 1.00 86.33  ? 322 ASP B O   1 
ATOM   3689  C CB  . ASP B 2 300 ? 166.801 108.164 130.726 1.00 86.33  ? 322 ASP B CB  1 
ATOM   3690  C CG  . ASP B 2 300 ? 165.835 107.038 131.036 1.00 86.33  ? 322 ASP B CG  1 
ATOM   3691  O OD1 . ASP B 2 300 ? 166.296 105.896 131.246 1.00 86.33  ? 322 ASP B OD1 1 
ATOM   3692  O OD2 . ASP B 2 300 ? 164.613 107.295 131.071 1.00 86.33  ? 322 ASP B OD2 1 
ATOM   3693  N N   . ARG B 2 301 ? 168.630 105.784 130.387 1.00 92.83  ? 323 ARG B N   1 
ATOM   3694  C CA  . ARG B 2 301 ? 169.355 104.824 129.571 1.00 92.83  ? 323 ARG B CA  1 
ATOM   3695  C C   . ARG B 2 301 ? 169.241 105.201 128.095 1.00 92.83  ? 323 ARG B C   1 
ATOM   3696  O O   . ARG B 2 301 ? 168.154 105.550 127.625 1.00 92.83  ? 323 ARG B O   1 
ATOM   3697  C CB  . ARG B 2 301 ? 168.809 103.414 129.798 1.00 92.83  ? 323 ARG B CB  1 
ATOM   3698  C CG  . ARG B 2 301 ? 169.370 102.361 128.858 1.00 92.83  ? 323 ARG B CG  1 
ATOM   3699  C CD  . ARG B 2 301 ? 168.850 100.978 129.211 1.00 92.83  ? 323 ARG B CD  1 
ATOM   3700  N NE  . ARG B 2 301 ? 169.302 99.964  128.264 1.00 92.83  ? 323 ARG B NE  1 
ATOM   3701  C CZ  . ARG B 2 301 ? 169.048 98.665  128.383 1.00 92.83  ? 323 ARG B CZ  1 
ATOM   3702  N NH1 . ARG B 2 301 ? 168.345 98.217  129.414 1.00 92.83  ? 323 ARG B NH1 1 
ATOM   3703  N NH2 . ARG B 2 301 ? 169.499 97.812  127.473 1.00 92.83  ? 323 ARG B NH2 1 
ATOM   3704  N N   . PRO B 2 302 ? 170.342 105.156 127.345 1.00 86.34  ? 324 PRO B N   1 
ATOM   3705  C CA  . PRO B 2 302 ? 170.272 105.483 125.917 1.00 86.34  ? 324 PRO B CA  1 
ATOM   3706  C C   . PRO B 2 302 ? 169.383 104.502 125.168 1.00 86.34  ? 324 PRO B C   1 
ATOM   3707  O O   . PRO B 2 302 ? 169.218 103.346 125.565 1.00 86.34  ? 324 PRO B O   1 
ATOM   3708  C CB  . PRO B 2 302 ? 171.731 105.383 125.455 1.00 86.34  ? 324 PRO B CB  1 
ATOM   3709  C CG  . PRO B 2 302 ? 172.543 105.512 126.704 1.00 86.34  ? 324 PRO B CG  1 
ATOM   3710  C CD  . PRO B 2 302 ? 171.721 104.889 127.786 1.00 86.34  ? 324 PRO B CD  1 
ATOM   3711  N N   . SER B 2 303 ? 168.805 104.982 124.068 1.00 90.76  ? 325 SER B N   1 
ATOM   3712  C CA  . SER B 2 303 ? 167.847 104.196 123.297 1.00 90.76  ? 325 SER B CA  1 
ATOM   3713  C C   . SER B 2 303 ? 168.523 103.422 122.168 1.00 90.76  ? 325 SER B C   1 
ATOM   3714  O O   . SER B 2 303 ? 168.429 102.192 122.105 1.00 90.76  ? 325 SER B O   1 
ATOM   3715  C CB  . SER B 2 303 ? 166.752 105.112 122.739 1.00 90.76  ? 325 SER B CB  1 
ATOM   3716  O OG  . SER B 2 303 ? 167.315 106.259 122.126 1.00 90.76  ? 325 SER B OG  1 
ATOM   3717  N N   . ARG B 2 304 ? 169.206 104.128 121.273 1.00 90.04  ? 326 ARG B N   1 
ATOM   3718  C CA  . ARG B 2 304 ? 169.784 103.431 120.134 1.00 90.04  ? 326 ARG B CA  1 
ATOM   3719  C C   . ARG B 2 304 ? 171.272 103.185 120.347 1.00 90.04  ? 326 ARG B C   1 
ATOM   3720  O O   . ARG B 2 304 ? 171.993 104.087 120.787 1.00 90.04  ? 326 ARG B O   1 
ATOM   3721  C CB  . ARG B 2 304 ? 169.582 104.240 118.852 1.00 90.04  ? 326 ARG B CB  1 
ATOM   3722  C CG  . ARG B 2 304 ? 169.947 103.499 117.576 1.00 90.04  ? 326 ARG B CG  1 
ATOM   3723  C CD  . ARG B 2 304 ? 169.602 104.322 116.347 1.00 90.04  ? 326 ARG B CD  1 
ATOM   3724  N NE  . ARG B 2 304 ? 170.343 105.579 116.308 1.00 90.04  ? 326 ARG B NE  1 
ATOM   3725  C CZ  . ARG B 2 304 ? 171.474 105.758 115.633 1.00 90.04  ? 326 ARG B CZ  1 
ATOM   3726  N NH1 . ARG B 2 304 ? 171.997 104.760 114.935 1.00 90.04  ? 326 ARG B NH1 1 
ATOM   3727  N NH2 . ARG B 2 304 ? 172.081 106.937 115.654 1.00 90.04  ? 326 ARG B NH2 1 
ATOM   3728  N N   . PRO B 2 305 ? 171.755 101.976 120.052 1.00 91.06  ? 327 PRO B N   1 
ATOM   3729  C CA  . PRO B 2 305 ? 173.189 101.720 120.168 1.00 91.06  ? 327 PRO B CA  1 
ATOM   3730  C C   . PRO B 2 305 ? 173.958 102.474 119.100 1.00 91.06  ? 327 PRO B C   1 
ATOM   3731  O O   . PRO B 2 305 ? 173.430 102.743 118.006 1.00 91.06  ? 327 PRO B O   1 
ATOM   3732  C CB  . PRO B 2 305 ? 173.294 100.197 119.969 1.00 91.06  ? 327 PRO B CB  1 
ATOM   3733  C CG  . PRO B 2 305 ? 172.072 99.832  119.202 1.00 91.06  ? 327 PRO B CG  1 
ATOM   3734  C CD  . PRO B 2 305 ? 171.001 100.769 119.675 1.00 91.06  ? 327 PRO B CD  1 
ATOM   3735  N N   . PRO B 2 306 ? 175.208 102.841 119.368 1.00 90.15  ? 328 PRO B N   1 
ATOM   3736  C CA  . PRO B 2 306 ? 175.981 103.611 118.389 1.00 90.15  ? 328 PRO B CA  1 
ATOM   3737  C C   . PRO B 2 306 ? 176.323 102.784 117.159 1.00 90.15  ? 328 PRO B C   1 
ATOM   3738  O O   . PRO B 2 306 ? 176.272 101.553 117.161 1.00 90.15  ? 328 PRO B O   1 
ATOM   3739  C CB  . PRO B 2 306 ? 177.249 104.004 119.157 1.00 90.15  ? 328 PRO B CB  1 
ATOM   3740  C CG  . PRO B 2 306 ? 176.921 103.780 120.605 1.00 90.15  ? 328 PRO B CG  1 
ATOM   3741  C CD  . PRO B 2 306 ? 175.946 102.651 120.626 1.00 90.15  ? 328 PRO B CD  1 
ATOM   3742  N N   . SER B 2 307 ? 176.680 103.495 116.092 1.00 107.63 ? 329 SER B N   1 
ATOM   3743  C CA  . SER B 2 307 ? 177.054 102.843 114.845 1.00 107.63 ? 329 SER B CA  1 
ATOM   3744  C C   . SER B 2 307 ? 178.398 102.141 114.993 1.00 107.63 ? 329 SER B C   1 
ATOM   3745  O O   . SER B 2 307 ? 179.313 102.645 115.649 1.00 107.63 ? 329 SER B O   1 
ATOM   3746  C CB  . SER B 2 307 ? 177.116 103.865 113.711 1.00 107.63 ? 329 SER B CB  1 
ATOM   3747  O OG  . SER B 2 307 ? 177.792 105.041 114.120 1.00 107.63 ? 329 SER B OG  1 
ATOM   3748  N N   . PHE B 2 308 ? 178.513 100.969 114.373 1.00 125.03 ? 330 PHE B N   1 
ATOM   3749  C CA  . PHE B 2 308 ? 179.701 100.137 114.482 1.00 125.03 ? 330 PHE B CA  1 
ATOM   3750  C C   . PHE B 2 308 ? 180.144 99.686  113.098 1.00 125.03 ? 330 PHE B C   1 
ATOM   3751  O O   . PHE B 2 308 ? 179.319 99.419  112.220 1.00 125.03 ? 330 PHE B O   1 
ATOM   3752  C CB  . PHE B 2 308 ? 179.439 98.914  115.376 1.00 125.03 ? 330 PHE B CB  1 
ATOM   3753  C CG  . PHE B 2 308 ? 180.678 98.145  115.736 1.00 125.03 ? 330 PHE B CG  1 
ATOM   3754  C CD1 . PHE B 2 308 ? 180.643 96.764  115.843 1.00 125.03 ? 330 PHE B CD1 1 
ATOM   3755  C CD2 . PHE B 2 308 ? 181.874 98.799  115.974 1.00 125.03 ? 330 PHE B CD2 1 
ATOM   3756  C CE1 . PHE B 2 308 ? 181.778 96.051  116.175 1.00 125.03 ? 330 PHE B CE1 1 
ATOM   3757  C CE2 . PHE B 2 308 ? 183.014 98.091  116.307 1.00 125.03 ? 330 PHE B CE2 1 
ATOM   3758  C CZ  . PHE B 2 308 ? 182.965 96.715  116.408 1.00 125.03 ? 330 PHE B CZ  1 
ATOM   3759  N N   . TRP B 2 309 ? 181.459 99.607  112.912 1.00 138.16 ? 331 TRP B N   1 
ATOM   3760  C CA  . TRP B 2 309 ? 182.034 99.150  111.655 1.00 138.16 ? 331 TRP B CA  1 
ATOM   3761  C C   . TRP B 2 309 ? 183.465 98.702  111.915 1.00 138.16 ? 331 TRP B C   1 
ATOM   3762  O O   . TRP B 2 309 ? 184.070 99.059  112.929 1.00 138.16 ? 331 TRP B O   1 
ATOM   3763  C CB  . TRP B 2 309 ? 181.985 100.247 110.583 1.00 138.16 ? 331 TRP B CB  1 
ATOM   3764  C CG  . TRP B 2 309 ? 182.400 99.788  109.216 1.00 138.16 ? 331 TRP B CG  1 
ATOM   3765  C CD1 . TRP B 2 309 ? 183.471 100.228 108.495 1.00 138.16 ? 331 TRP B CD1 1 
ATOM   3766  C CD2 . TRP B 2 309 ? 181.753 98.796  108.407 1.00 138.16 ? 331 TRP B CD2 1 
ATOM   3767  N NE1 . TRP B 2 309 ? 183.531 99.575  107.288 1.00 138.16 ? 331 TRP B NE1 1 
ATOM   3768  C CE2 . TRP B 2 309 ? 182.488 98.691  107.210 1.00 138.16 ? 331 TRP B CE2 1 
ATOM   3769  C CE3 . TRP B 2 309 ? 180.625 97.989  108.579 1.00 138.16 ? 331 TRP B CE3 1 
ATOM   3770  C CZ2 . TRP B 2 309 ? 182.131 97.811  106.190 1.00 138.16 ? 331 TRP B CZ2 1 
ATOM   3771  C CZ3 . TRP B 2 309 ? 180.273 97.117  107.566 1.00 138.16 ? 331 TRP B CZ3 1 
ATOM   3772  C CH2 . TRP B 2 309 ? 181.023 97.035  106.387 1.00 138.16 ? 331 TRP B CH2 1 
ATOM   3773  N N   . TYR B 2 310 ? 183.996 97.905  110.990 1.00 150.11 ? 332 TYR B N   1 
ATOM   3774  C CA  . TYR B 2 310 ? 185.352 97.393  111.104 1.00 150.11 ? 332 TYR B CA  1 
ATOM   3775  C C   . TYR B 2 310 ? 186.048 97.483  109.755 1.00 150.11 ? 332 TYR B C   1 
ATOM   3776  O O   . TYR B 2 310 ? 185.406 97.439  108.702 1.00 150.11 ? 332 TYR B O   1 
ATOM   3777  C CB  . TYR B 2 310 ? 185.368 95.942  111.610 1.00 150.11 ? 332 TYR B CB  1 
ATOM   3778  C CG  . TYR B 2 310 ? 185.019 94.915  110.556 1.00 150.11 ? 332 TYR B CG  1 
ATOM   3779  C CD1 . TYR B 2 310 ? 183.700 94.706  110.173 1.00 150.11 ? 332 TYR B CD1 1 
ATOM   3780  C CD2 . TYR B 2 310 ? 186.007 94.152  109.947 1.00 150.11 ? 332 TYR B CD2 1 
ATOM   3781  C CE1 . TYR B 2 310 ? 183.376 93.767  109.211 1.00 150.11 ? 332 TYR B CE1 1 
ATOM   3782  C CE2 . TYR B 2 310 ? 185.692 93.211  108.985 1.00 150.11 ? 332 TYR B CE2 1 
ATOM   3783  C CZ  . TYR B 2 310 ? 184.376 93.023  108.621 1.00 150.11 ? 332 TYR B CZ  1 
ATOM   3784  O OH  . TYR B 2 310 ? 184.057 92.088  107.663 1.00 150.11 ? 332 TYR B OH  1 
ATOM   3785  N N   . LYS B 2 311 ? 187.372 97.611  109.799 1.00 158.96 ? 333 LYS B N   1 
ATOM   3786  C CA  . LYS B 2 311 ? 188.194 97.675  108.600 1.00 158.96 ? 333 LYS B CA  1 
ATOM   3787  C C   . LYS B 2 311 ? 189.412 96.785  108.785 1.00 158.96 ? 333 LYS B C   1 
ATOM   3788  O O   . LYS B 2 311 ? 190.050 96.807  109.842 1.00 158.96 ? 333 LYS B O   1 
ATOM   3789  C CB  . LYS B 2 311 ? 188.631 99.114  108.294 1.00 158.96 ? 333 LYS B CB  1 
ATOM   3790  C CG  . LYS B 2 311 ? 189.519 99.248  107.066 1.00 158.96 ? 333 LYS B CG  1 
ATOM   3791  C CD  . LYS B 2 311 ? 189.879 100.700 106.797 1.00 158.96 ? 333 LYS B CD  1 
ATOM   3792  C CE  . LYS B 2 311 ? 188.653 101.514 106.421 1.00 158.96 ? 333 LYS B CE  1 
ATOM   3793  N NZ  . LYS B 2 311 ? 188.014 101.013 105.173 1.00 158.96 ? 333 LYS B NZ  1 
ATOM   3794  N N   . THR B 2 312 ? 189.729 96.004  107.756 1.00 180.63 ? 334 THR B N   1 
ATOM   3795  C CA  . THR B 2 312 ? 190.838 95.060  107.793 1.00 180.63 ? 334 THR B CA  1 
ATOM   3796  C C   . THR B 2 312 ? 191.807 95.372  106.662 1.00 180.63 ? 334 THR B C   1 
ATOM   3797  O O   . THR B 2 312 ? 191.401 95.463  105.499 1.00 180.63 ? 334 THR B O   1 
ATOM   3798  C CB  . THR B 2 312 ? 190.340 93.617  107.675 1.00 180.63 ? 334 THR B CB  1 
ATOM   3799  O OG1 . THR B 2 312 ? 189.473 93.317  108.777 1.00 180.63 ? 334 THR B OG1 1 
ATOM   3800  C CG2 . THR B 2 312 ? 191.511 92.645  107.680 1.00 180.63 ? 334 THR B CG2 1 
ATOM   3801  N N   . ASN B 2 313 ? 193.091 95.537  107.010 1.00 207.12 ? 335 ASN B N   1 
ATOM   3802  C CA  . ASN B 2 313 ? 194.128 95.787  106.023 1.00 207.12 ? 335 ASN B CA  1 
ATOM   3803  C C   . ASN B 2 313 ? 194.672 94.471  105.474 1.00 207.12 ? 335 ASN B C   1 
ATOM   3804  O O   . ASN B 2 313 ? 194.711 93.462  106.185 1.00 207.12 ? 335 ASN B O   1 
ATOM   3805  C CB  . ASN B 2 313 ? 195.267 96.595  106.639 1.00 207.12 ? 335 ASN B CB  1 
ATOM   3806  C CG  . ASN B 2 313 ? 195.902 95.898  107.825 1.00 207.12 ? 335 ASN B CG  1 
ATOM   3807  O OD1 . ASN B 2 313 ? 196.824 95.098  107.669 1.00 207.12 ? 335 ASN B OD1 1 
ATOM   3808  N ND2 . ASN B 2 313 ? 195.410 96.199  109.021 1.00 207.12 ? 335 ASN B ND2 1 
ATOM   3809  N N   . PRO B 2 314 ? 195.096 94.452  104.207 1.00 224.47 ? 336 PRO B N   1 
ATOM   3810  C CA  . PRO B 2 314 ? 195.616 93.207  103.624 1.00 224.47 ? 336 PRO B CA  1 
ATOM   3811  C C   . PRO B 2 314 ? 196.944 92.784  104.233 1.00 224.47 ? 336 PRO B C   1 
ATOM   3812  O O   . PRO B 2 314 ? 197.961 93.465  104.065 1.00 224.47 ? 336 PRO B O   1 
ATOM   3813  C CB  . PRO B 2 314 ? 195.762 93.550  102.136 1.00 224.47 ? 336 PRO B CB  1 
ATOM   3814  C CG  . PRO B 2 314 ? 195.905 95.034  102.102 1.00 224.47 ? 336 PRO B CG  1 
ATOM   3815  C CD  . PRO B 2 314 ? 195.060 95.552  103.228 1.00 224.47 ? 336 PRO B CD  1 
ATOM   3816  N N   . SER B 2 315 ? 196.941 91.657  104.945 1.00 243.86 ? 337 SER B N   1 
ATOM   3817  C CA  . SER B 2 315 ? 198.142 91.094  105.565 1.00 243.86 ? 337 SER B CA  1 
ATOM   3818  C C   . SER B 2 315 ? 198.219 89.626  105.154 1.00 243.86 ? 337 SER B C   1 
ATOM   3819  O O   . SER B 2 315 ? 197.701 88.748  105.850 1.00 243.86 ? 337 SER B O   1 
ATOM   3820  C CB  . SER B 2 315 ? 198.110 91.261  107.081 1.00 243.86 ? 337 SER B CB  1 
ATOM   3821  O OG  . SER B 2 315 ? 198.314 92.614  107.449 1.00 243.86 ? 337 SER B OG  1 
ATOM   3822  N N   . HIS B 2 316 ? 198.869 89.364  104.023 1.00 262.65 ? 338 HIS B N   1 
ATOM   3823  C CA  . HIS B 2 316 ? 198.979 88.015  103.486 1.00 262.65 ? 338 HIS B CA  1 
ATOM   3824  C C   . HIS B 2 316 ? 200.233 87.339  104.026 1.00 262.65 ? 338 HIS B C   1 
ATOM   3825  O O   . HIS B 2 316 ? 201.306 87.949  104.069 1.00 262.65 ? 338 HIS B O   1 
ATOM   3826  C CB  . HIS B 2 316 ? 199.010 88.045  101.958 1.00 262.65 ? 338 HIS B CB  1 
ATOM   3827  C CG  . HIS B 2 316 ? 198.345 86.867  101.316 1.00 262.65 ? 338 HIS B CG  1 
ATOM   3828  N ND1 . HIS B 2 316 ? 198.662 85.566  101.640 1.00 262.65 ? 338 HIS B ND1 1 
ATOM   3829  C CD2 . HIS B 2 316 ? 197.380 86.795  100.369 1.00 262.65 ? 338 HIS B CD2 1 
ATOM   3830  C CE1 . HIS B 2 316 ? 197.921 84.742  100.921 1.00 262.65 ? 338 HIS B CE1 1 
ATOM   3831  N NE2 . HIS B 2 316 ? 197.135 85.462  100.141 1.00 262.65 ? 338 HIS B NE2 1 
ATOM   3832  N N   . GLY B 2 317 ? 200.092 86.082  104.434 1.00 264.05 ? 339 GLY B N   1 
ATOM   3833  C CA  . GLY B 2 317 ? 201.202 85.309  104.946 1.00 264.05 ? 339 GLY B CA  1 
ATOM   3834  C C   . GLY B 2 317 ? 201.328 85.257  106.452 1.00 264.05 ? 339 GLY B C   1 
ATOM   3835  O O   . GLY B 2 317 ? 202.385 84.854  106.950 1.00 264.05 ? 339 GLY B O   1 
ATOM   3836  N N   . GLN B 2 318 ? 200.293 85.649  107.191 1.00 250.50 ? 340 GLN B N   1 
ATOM   3837  C CA  . GLN B 2 318 ? 200.320 85.633  108.645 1.00 250.50 ? 340 GLN B CA  1 
ATOM   3838  C C   . GLN B 2 318 ? 199.082 84.926  109.175 1.00 250.50 ? 340 GLN B C   1 
ATOM   3839  O O   . GLN B 2 318 ? 198.011 84.968  108.563 1.00 250.50 ? 340 GLN B O   1 
ATOM   3840  C CB  . GLN B 2 318 ? 200.395 87.053  109.224 1.00 250.50 ? 340 GLN B CB  1 
ATOM   3841  C CG  . GLN B 2 318 ? 201.696 87.779  108.927 1.00 250.50 ? 340 GLN B CG  1 
ATOM   3842  C CD  . GLN B 2 318 ? 201.761 89.145  109.580 1.00 250.50 ? 340 GLN B CD  1 
ATOM   3843  O OE1 . GLN B 2 318 ? 200.802 89.591  110.210 1.00 250.50 ? 340 GLN B OE1 1 
ATOM   3844  N NE2 . GLN B 2 318 ? 202.897 89.817  109.434 1.00 250.50 ? 340 GLN B NE2 1 
ATOM   3845  N N   . GLU B 2 319 ? 199.242 84.270  110.327 1.00 235.35 ? 341 GLU B N   1 
ATOM   3846  C CA  . GLU B 2 319 ? 198.110 83.600  110.958 1.00 235.35 ? 341 GLU B CA  1 
ATOM   3847  C C   . GLU B 2 319 ? 197.134 84.609  111.551 1.00 235.35 ? 341 GLU B C   1 
ATOM   3848  O O   . GLU B 2 319 ? 195.915 84.458  111.412 1.00 235.35 ? 341 GLU B O   1 
ATOM   3849  C CB  . GLU B 2 319 ? 198.608 82.634  112.034 1.00 235.35 ? 341 GLU B CB  1 
ATOM   3850  C CG  . GLU B 2 319 ? 197.522 82.129  112.971 1.00 235.35 ? 341 GLU B CG  1 
ATOM   3851  C CD  . GLU B 2 319 ? 196.519 81.231  112.275 1.00 235.35 ? 341 GLU B CD  1 
ATOM   3852  O OE1 . GLU B 2 319 ? 196.890 80.587  111.271 1.00 235.35 ? 341 GLU B OE1 1 
ATOM   3853  O OE2 . GLU B 2 319 ? 195.358 81.169  112.732 1.00 235.35 ? 341 GLU B OE2 1 
ATOM   3854  N N   . TYR B 2 320 ? 197.650 85.644  112.208 1.00 228.64 ? 342 TYR B N   1 
ATOM   3855  C CA  . TYR B 2 320 ? 196.815 86.666  112.820 1.00 228.64 ? 342 TYR B CA  1 
ATOM   3856  C C   . TYR B 2 320 ? 196.595 87.821  111.853 1.00 228.64 ? 342 TYR B C   1 
ATOM   3857  O O   . TYR B 2 320 ? 197.514 88.236  111.141 1.00 228.64 ? 342 TYR B O   1 
ATOM   3858  C CB  . TYR B 2 320 ? 197.451 87.182  114.111 1.00 228.64 ? 342 TYR B CB  1 
ATOM   3859  C CG  . TYR B 2 320 ? 197.615 86.130  115.184 1.00 228.64 ? 342 TYR B CG  1 
ATOM   3860  C CD1 . TYR B 2 320 ? 196.623 85.917  116.132 1.00 228.64 ? 342 TYR B CD1 1 
ATOM   3861  C CD2 . TYR B 2 320 ? 198.764 85.352  115.252 1.00 228.64 ? 342 TYR B CD2 1 
ATOM   3862  C CE1 . TYR B 2 320 ? 196.769 84.957  117.116 1.00 228.64 ? 342 TYR B CE1 1 
ATOM   3863  C CE2 . TYR B 2 320 ? 198.919 84.390  116.232 1.00 228.64 ? 342 TYR B CE2 1 
ATOM   3864  C CZ  . TYR B 2 320 ? 197.919 84.196  117.161 1.00 228.64 ? 342 TYR B CZ  1 
ATOM   3865  O OH  . TYR B 2 320 ? 198.069 83.240  118.139 1.00 228.64 ? 342 TYR B OH  1 
ATOM   3866  N N   . ARG B 2 321 ? 195.370 88.337  111.832 1.00 210.89 ? 343 ARG B N   1 
ATOM   3867  C CA  . ARG B 2 321 ? 195.005 89.473  111.000 1.00 210.89 ? 343 ARG B CA  1 
ATOM   3868  C C   . ARG B 2 321 ? 194.729 90.686  111.879 1.00 210.89 ? 343 ARG B C   1 
ATOM   3869  O O   . ARG B 2 321 ? 194.150 90.561  112.963 1.00 210.89 ? 343 ARG B O   1 
ATOM   3870  C CB  . ARG B 2 321 ? 193.777 89.158  110.140 1.00 210.89 ? 343 ARG B CB  1 
ATOM   3871  C CG  . ARG B 2 321 ? 192.607 88.564  110.911 1.00 210.89 ? 343 ARG B CG  1 
ATOM   3872  C CD  . ARG B 2 321 ? 191.391 88.377  110.017 1.00 210.89 ? 343 ARG B CD  1 
ATOM   3873  N NE  . ARG B 2 321 ? 190.321 87.645  110.690 1.00 210.89 ? 343 ARG B NE  1 
ATOM   3874  C CZ  . ARG B 2 321 ? 189.116 87.438  110.171 1.00 210.89 ? 343 ARG B CZ  1 
ATOM   3875  N NH1 . ARG B 2 321 ? 188.820 87.908  108.967 1.00 210.89 ? 343 ARG B NH1 1 
ATOM   3876  N NH2 . ARG B 2 321 ? 188.204 86.760  110.855 1.00 210.89 ? 343 ARG B NH2 1 
ATOM   3877  N N   . SER B 2 322 ? 195.151 91.857  111.410 1.00 195.49 ? 344 SER B N   1 
ATOM   3878  C CA  . SER B 2 322 ? 194.960 93.101  112.143 1.00 195.49 ? 344 SER B CA  1 
ATOM   3879  C C   . SER B 2 322 ? 193.654 93.750  111.699 1.00 195.49 ? 344 SER B C   1 
ATOM   3880  O O   . SER B 2 322 ? 193.465 94.028  110.510 1.00 195.49 ? 344 SER B O   1 
ATOM   3881  C CB  . SER B 2 322 ? 196.138 94.048  111.917 1.00 195.49 ? 344 SER B CB  1 
ATOM   3882  O OG  . SER B 2 322 ? 196.243 94.417  110.553 1.00 195.49 ? 344 SER B OG  1 
ATOM   3883  N N   . VAL B 2 323 ? 192.758 93.987  112.653 1.00 170.57 ? 345 VAL B N   1 
ATOM   3884  C CA  . VAL B 2 323 ? 191.454 94.581  112.388 1.00 170.57 ? 345 VAL B CA  1 
ATOM   3885  C C   . VAL B 2 323 ? 191.308 95.829  113.245 1.00 170.57 ? 345 VAL B C   1 
ATOM   3886  O O   . VAL B 2 323 ? 191.618 95.812  114.442 1.00 170.57 ? 345 VAL B O   1 
ATOM   3887  C CB  . VAL B 2 323 ? 190.309 93.584  112.668 1.00 170.57 ? 345 VAL B CB  1 
ATOM   3888  C CG1 . VAL B 2 323 ? 188.958 94.262  112.510 1.00 170.57 ? 345 VAL B CG1 1 
ATOM   3889  C CG2 . VAL B 2 323 ? 190.419 92.378  111.748 1.00 170.57 ? 345 VAL B CG2 1 
ATOM   3890  N N   . ARG B 2 324 ? 190.837 96.911  112.631 1.00 143.07 ? 346 ARG B N   1 
ATOM   3891  C CA  . ARG B 2 324 ? 190.661 98.199  113.298 1.00 143.07 ? 346 ARG B CA  1 
ATOM   3892  C C   . ARG B 2 324 ? 189.168 98.423  113.521 1.00 143.07 ? 346 ARG B C   1 
ATOM   3893  O O   . ARG B 2 324 ? 188.421 98.681  112.573 1.00 143.07 ? 346 ARG B O   1 
ATOM   3894  C CB  . ARG B 2 324 ? 191.278 99.324  112.473 1.00 143.07 ? 346 ARG B CB  1 
ATOM   3895  C CG  . ARG B 2 324 ? 190.956 100.719 112.980 1.00 143.07 ? 346 ARG B CG  1 
ATOM   3896  C CD  . ARG B 2 324 ? 191.389 101.778 111.981 1.00 143.07 ? 346 ARG B CD  1 
ATOM   3897  N NE  . ARG B 2 324 ? 190.929 103.110 112.361 1.00 143.07 ? 346 ARG B NE  1 
ATOM   3898  C CZ  . ARG B 2 324 ? 191.101 104.198 111.619 1.00 143.07 ? 346 ARG B CZ  1 
ATOM   3899  N NH1 . ARG B 2 324 ? 191.724 104.115 110.452 1.00 143.07 ? 346 ARG B NH1 1 
ATOM   3900  N NH2 . ARG B 2 324 ? 190.649 105.371 112.043 1.00 143.07 ? 346 ARG B NH2 1 
ATOM   3901  N N   . LEU B 2 325 ? 188.738 98.321  114.776 1.00 129.57 ? 347 LEU B N   1 
ATOM   3902  C CA  . LEU B 2 325 ? 187.341 98.543  115.128 1.00 129.57 ? 347 LEU B CA  1 
ATOM   3903  C C   . LEU B 2 325 ? 187.081 100.039 115.254 1.00 129.57 ? 347 LEU B C   1 
ATOM   3904  O O   . LEU B 2 325 ? 187.769 100.733 116.011 1.00 129.57 ? 347 LEU B O   1 
ATOM   3905  C CB  . LEU B 2 325 ? 186.997 97.825  116.430 1.00 129.57 ? 347 LEU B CB  1 
ATOM   3906  C CG  . LEU B 2 325 ? 187.389 96.350  116.544 1.00 129.57 ? 347 LEU B CG  1 
ATOM   3907  C CD1 . LEU B 2 325 ? 186.739 95.720  117.766 1.00 129.57 ? 347 LEU B CD1 1 
ATOM   3908  C CD2 . LEU B 2 325 ? 187.000 95.590  115.287 1.00 129.57 ? 347 LEU B CD2 1 
ATOM   3909  N N   . ILE B 2 326 ? 186.092 100.536 114.515 1.00 120.32 ? 348 ILE B N   1 
ATOM   3910  C CA  . ILE B 2 326 ? 185.740 101.949 114.525 1.00 120.32 ? 348 ILE B CA  1 
ATOM   3911  C C   . ILE B 2 326 ? 184.274 102.091 114.906 1.00 120.32 ? 348 ILE B C   1 
ATOM   3912  O O   . ILE B 2 326 ? 183.448 101.220 114.618 1.00 120.32 ? 348 ILE B O   1 
ATOM   3913  C CB  . ILE B 2 326 ? 186.018 102.622 113.162 1.00 120.32 ? 348 ILE B CB  1 
ATOM   3914  C CG1 . ILE B 2 326 ? 185.215 101.942 112.052 1.00 120.32 ? 348 ILE B CG1 1 
ATOM   3915  C CG2 . ILE B 2 326 ? 187.503 102.586 112.842 1.00 120.32 ? 348 ILE B CG2 1 
ATOM   3916  C CD1 . ILE B 2 326 ? 185.464 102.518 110.677 1.00 120.32 ? 348 ILE B CD1 1 
ATOM   3917  N N   . TRP B 2 327 ? 183.957 103.202 115.566 1.00 106.84 ? 349 TRP B N   1 
ATOM   3918  C CA  . TRP B 2 327 ? 182.585 103.498 115.951 1.00 106.84 ? 349 TRP B CA  1 
ATOM   3919  C C   . TRP B 2 327 ? 182.481 104.975 116.294 1.00 106.84 ? 349 TRP B C   1 
ATOM   3920  O O   . TRP B 2 327 ? 183.451 105.590 116.743 1.00 106.84 ? 349 TRP B O   1 
ATOM   3921  C CB  . TRP B 2 327 ? 182.129 102.637 117.135 1.00 106.84 ? 349 TRP B CB  1 
ATOM   3922  C CG  . TRP B 2 327 ? 182.879 102.895 118.400 1.00 106.84 ? 349 TRP B CG  1 
ATOM   3923  C CD1 . TRP B 2 327 ? 182.528 103.754 119.400 1.00 106.84 ? 349 TRP B CD1 1 
ATOM   3924  C CD2 . TRP B 2 327 ? 184.107 102.283 118.808 1.00 106.84 ? 349 TRP B CD2 1 
ATOM   3925  N NE1 . TRP B 2 327 ? 183.464 103.718 120.404 1.00 106.84 ? 349 TRP B NE1 1 
ATOM   3926  C CE2 . TRP B 2 327 ? 184.444 102.822 120.065 1.00 106.84 ? 349 TRP B CE2 1 
ATOM   3927  C CE3 . TRP B 2 327 ? 184.955 101.333 118.231 1.00 106.84 ? 349 TRP B CE3 1 
ATOM   3928  C CZ2 . TRP B 2 327 ? 185.593 102.444 120.756 1.00 106.84 ? 349 TRP B CZ2 1 
ATOM   3929  C CZ3 . TRP B 2 327 ? 186.096 100.959 118.919 1.00 106.84 ? 349 TRP B CZ3 1 
ATOM   3930  C CH2 . TRP B 2 327 ? 186.403 101.513 120.168 1.00 106.84 ? 349 TRP B CH2 1 
ATOM   3931  N N   . LYS B 2 328 ? 181.296 105.534 116.077 1.00 101.99 ? 350 LYS B N   1 
ATOM   3932  C CA  . LYS B 2 328 ? 181.039 106.947 116.299 1.00 101.99 ? 350 LYS B CA  1 
ATOM   3933  C C   . LYS B 2 328 ? 180.239 107.148 117.579 1.00 101.99 ? 350 LYS B C   1 
ATOM   3934  O O   . LYS B 2 328 ? 179.585 106.233 118.084 1.00 101.99 ? 350 LYS B O   1 
ATOM   3935  C CB  . LYS B 2 328 ? 180.289 107.561 115.112 1.00 101.99 ? 350 LYS B CB  1 
ATOM   3936  C CG  . LYS B 2 328 ? 181.092 107.586 113.821 1.00 101.99 ? 350 LYS B CG  1 
ATOM   3937  C CD  . LYS B 2 328 ? 180.345 108.316 112.718 1.00 101.99 ? 350 LYS B CD  1 
ATOM   3938  C CE  . LYS B 2 328 ? 181.194 108.431 111.464 1.00 101.99 ? 350 LYS B CE  1 
ATOM   3939  N NZ  . LYS B 2 328 ? 180.479 109.154 110.377 1.00 101.99 ? 350 LYS B NZ  1 
ATOM   3940  N N   . ALA B 2 329 ? 180.304 108.369 118.101 1.00 77.93  ? 351 ALA B N   1 
ATOM   3941  C CA  . ALA B 2 329 ? 179.592 108.710 119.320 1.00 77.93  ? 351 ALA B CA  1 
ATOM   3942  C C   . ALA B 2 329 ? 178.129 109.022 119.019 1.00 77.93  ? 351 ALA B C   1 
ATOM   3943  O O   . ALA B 2 329 ? 177.751 109.337 117.888 1.00 77.93  ? 351 ALA B O   1 
ATOM   3944  C CB  . ALA B 2 329 ? 180.250 109.901 120.015 1.00 77.93  ? 351 ALA B CB  1 
ATOM   3945  N N   . LEU B 2 330 ? 177.304 108.927 120.056 1.00 82.11  ? 352 LEU B N   1 
ATOM   3946  C CA  . LEU B 2 330 ? 175.884 109.207 119.895 1.00 82.11  ? 352 LEU B CA  1 
ATOM   3947  C C   . LEU B 2 330 ? 175.607 110.693 120.103 1.00 82.11  ? 352 LEU B C   1 
ATOM   3948  O O   . LEU B 2 330 ? 176.245 111.332 120.945 1.00 82.11  ? 352 LEU B O   1 
ATOM   3949  C CB  . LEU B 2 330 ? 175.057 108.393 120.885 1.00 82.11  ? 352 LEU B CB  1 
ATOM   3950  C CG  . LEU B 2 330 ? 174.916 106.898 120.595 1.00 82.11  ? 352 LEU B CG  1 
ATOM   3951  C CD1 . LEU B 2 330 ? 174.280 106.184 121.776 1.00 82.11  ? 352 LEU B CD1 1 
ATOM   3952  C CD2 . LEU B 2 330 ? 174.108 106.671 119.327 1.00 82.11  ? 352 LEU B CD2 1 
ATOM   3953  N N   . PRO B 2 331 ? 174.671 111.261 119.347 1.00 82.52  ? 353 PRO B N   1 
ATOM   3954  C CA  . PRO B 2 331 ? 174.304 112.666 119.552 1.00 82.52  ? 353 PRO B CA  1 
ATOM   3955  C C   . PRO B 2 331 ? 173.618 112.865 120.895 1.00 82.52  ? 353 PRO B C   1 
ATOM   3956  O O   . PRO B 2 331 ? 173.244 111.918 121.590 1.00 82.52  ? 353 PRO B O   1 
ATOM   3957  C CB  . PRO B 2 331 ? 173.352 112.966 118.389 1.00 82.52  ? 353 PRO B CB  1 
ATOM   3958  C CG  . PRO B 2 331 ? 173.598 111.873 117.389 1.00 82.52  ? 353 PRO B CG  1 
ATOM   3959  C CD  . PRO B 2 331 ? 173.973 110.671 118.194 1.00 82.52  ? 353 PRO B CD  1 
ATOM   3960  N N   . LEU B 2 332 ? 173.448 114.138 121.256 1.00 87.44  ? 354 LEU B N   1 
ATOM   3961  C CA  . LEU B 2 332 ? 172.831 114.475 122.533 1.00 87.44  ? 354 LEU B CA  1 
ATOM   3962  C C   . LEU B 2 332 ? 171.345 114.140 122.571 1.00 87.44  ? 354 LEU B C   1 
ATOM   3963  O O   . LEU B 2 332 ? 170.749 114.154 123.653 1.00 87.44  ? 354 LEU B O   1 
ATOM   3964  C CB  . LEU B 2 332 ? 173.038 115.958 122.842 1.00 87.44  ? 354 LEU B CB  1 
ATOM   3965  C CG  . LEU B 2 332 ? 174.492 116.426 122.917 1.00 87.44  ? 354 LEU B CG  1 
ATOM   3966  C CD1 . LEU B 2 332 ? 174.565 117.899 123.286 1.00 87.44  ? 354 LEU B CD1 1 
ATOM   3967  C CD2 . LEU B 2 332 ? 175.278 115.580 123.907 1.00 87.44  ? 354 LEU B CD2 1 
ATOM   3968  N N   . SER B 2 333 ? 170.736 113.843 121.424 1.00 93.18  ? 355 SER B N   1 
ATOM   3969  C CA  . SER B 2 333 ? 169.323 113.491 121.380 1.00 93.18  ? 355 SER B CA  1 
ATOM   3970  C C   . SER B 2 333 ? 169.070 112.007 121.599 1.00 93.18  ? 355 SER B C   1 
ATOM   3971  O O   . SER B 2 333 ? 167.978 111.639 122.047 1.00 93.18  ? 355 SER B O   1 
ATOM   3972  C CB  . SER B 2 333 ? 168.713 113.916 120.040 1.00 93.18  ? 355 SER B CB  1 
ATOM   3973  O OG  . SER B 2 333 ? 168.376 115.292 120.047 1.00 93.18  ? 355 SER B OG  1 
ATOM   3974  N N   . GLU B 2 334 ? 170.047 111.148 121.297 1.00 91.95  ? 356 GLU B N   1 
ATOM   3975  C CA  . GLU B 2 334 ? 169.897 109.712 121.481 1.00 91.95  ? 356 GLU B CA  1 
ATOM   3976  C C   . GLU B 2 334 ? 170.718 109.151 122.632 1.00 91.95  ? 356 GLU B C   1 
ATOM   3977  O O   . GLU B 2 334 ? 170.357 108.098 123.166 1.00 91.95  ? 356 GLU B O   1 
ATOM   3978  C CB  . GLU B 2 334 ? 170.277 108.964 120.195 1.00 91.95  ? 356 GLU B CB  1 
ATOM   3979  C CG  . GLU B 2 334 ? 169.516 109.417 118.962 1.00 91.95  ? 356 GLU B CG  1 
ATOM   3980  C CD  . GLU B 2 334 ? 169.710 108.483 117.784 1.00 91.95  ? 356 GLU B CD  1 
ATOM   3981  O OE1 . GLU B 2 334 ? 169.117 107.385 117.790 1.00 91.95  ? 356 GLU B OE1 1 
ATOM   3982  O OE2 . GLU B 2 334 ? 170.457 108.847 116.852 1.00 91.95  ? 356 GLU B OE2 1 
ATOM   3983  N N   . ALA B 2 335 ? 171.807 109.817 123.022 1.00 86.94  ? 357 ALA B N   1 
ATOM   3984  C CA  . ALA B 2 335 ? 172.618 109.315 124.127 1.00 86.94  ? 357 ALA B CA  1 
ATOM   3985  C C   . ALA B 2 335 ? 171.930 109.520 125.470 1.00 86.94  ? 357 ALA B C   1 
ATOM   3986  O O   . ALA B 2 335 ? 172.173 108.753 126.409 1.00 86.94  ? 357 ALA B O   1 
ATOM   3987  C CB  . ALA B 2 335 ? 173.988 109.992 124.125 1.00 86.94  ? 357 ALA B CB  1 
ATOM   3988  N N   . ASN B 2 336 ? 171.077 110.541 125.579 1.00 90.01  ? 358 ASN B N   1 
ATOM   3989  C CA  . ASN B 2 336 ? 170.336 110.841 126.806 1.00 90.01  ? 358 ASN B CA  1 
ATOM   3990  C C   . ASN B 2 336 ? 171.267 111.070 127.994 1.00 90.01  ? 358 ASN B C   1 
ATOM   3991  O O   . ASN B 2 336 ? 170.903 110.803 129.142 1.00 90.01  ? 358 ASN B O   1 
ATOM   3992  C CB  . ASN B 2 336 ? 169.324 109.738 127.128 1.00 90.01  ? 358 ASN B CB  1 
ATOM   3993  C CG  . ASN B 2 336 ? 168.463 109.371 125.937 1.00 90.01  ? 358 ASN B CG  1 
ATOM   3994  O OD1 . ASN B 2 336 ? 168.220 110.195 125.055 1.00 90.01  ? 358 ASN B OD1 1 
ATOM   3995  N ND2 . ASN B 2 336 ? 167.996 108.129 125.905 1.00 90.01  ? 358 ASN B ND2 1 
ATOM   3996  N N   . GLY B 2 337 ? 172.468 111.564 127.733 1.00 87.56  ? 359 GLY B N   1 
ATOM   3997  C CA  . GLY B 2 337 ? 173.425 111.803 128.792 1.00 87.56  ? 359 GLY B CA  1 
ATOM   3998  C C   . GLY B 2 337 ? 174.839 111.810 128.246 1.00 87.56  ? 359 GLY B C   1 
ATOM   3999  O O   . GLY B 2 337 ? 175.060 111.799 127.035 1.00 87.56  ? 359 GLY B O   1 
ATOM   4000  N N   . LYS B 2 338 ? 175.790 111.827 129.175 1.00 88.38  ? 360 LYS B N   1 
ATOM   4001  C CA  . LYS B 2 338 ? 177.207 111.867 128.838 1.00 88.38  ? 360 LYS B CA  1 
ATOM   4002  C C   . LYS B 2 338 ? 177.747 110.445 128.741 1.00 88.38  ? 360 LYS B C   1 
ATOM   4003  O O   . LYS B 2 338 ? 177.736 109.703 129.729 1.00 88.38  ? 360 LYS B O   1 
ATOM   4004  C CB  . LYS B 2 338 ? 177.986 112.670 129.879 1.00 88.38  ? 360 LYS B CB  1 
ATOM   4005  C CG  . LYS B 2 338 ? 179.419 112.978 129.479 1.00 88.38  ? 360 LYS B CG  1 
ATOM   4006  C CD  . LYS B 2 338 ? 179.468 113.867 128.247 1.00 88.38  ? 360 LYS B CD  1 
ATOM   4007  C CE  . LYS B 2 338 ? 180.899 114.114 127.801 1.00 88.38  ? 360 LYS B CE  1 
ATOM   4008  N NZ  . LYS B 2 338 ? 181.583 112.851 127.412 1.00 88.38  ? 360 LYS B NZ  1 
ATOM   4009  N N   . ILE B 2 339 ? 178.219 110.070 127.552 1.00 90.33  ? 361 ILE B N   1 
ATOM   4010  C CA  . ILE B 2 339 ? 178.792 108.745 127.354 1.00 90.33  ? 361 ILE B CA  1 
ATOM   4011  C C   . ILE B 2 339 ? 180.112 108.649 128.105 1.00 90.33  ? 361 ILE B C   1 
ATOM   4012  O O   . ILE B 2 339 ? 180.973 109.532 127.997 1.00 90.33  ? 361 ILE B O   1 
ATOM   4013  C CB  . ILE B 2 339 ? 178.979 108.459 125.856 1.00 90.33  ? 361 ILE B CB  1 
ATOM   4014  C CG1 . ILE B 2 339 ? 177.648 108.604 125.117 1.00 90.33  ? 361 ILE B CG1 1 
ATOM   4015  C CG2 . ILE B 2 339 ? 179.559 107.069 125.645 1.00 90.33  ? 361 ILE B CG2 1 
ATOM   4016  C CD1 . ILE B 2 339 ? 176.570 107.667 125.613 1.00 90.33  ? 361 ILE B CD1 1 
ATOM   4017  N N   . LEU B 2 340 ? 180.278 107.572 128.874 1.00 84.78  ? 362 LEU B N   1 
ATOM   4018  C CA  . LEU B 2 340 ? 181.488 107.380 129.668 1.00 84.78  ? 362 LEU B CA  1 
ATOM   4019  C C   . LEU B 2 340 ? 182.527 106.546 128.921 1.00 84.78  ? 362 LEU B C   1 
ATOM   4020  O O   . LEU B 2 340 ? 183.667 106.984 128.739 1.00 84.78  ? 362 LEU B O   1 
ATOM   4021  C CB  . LEU B 2 340 ? 181.136 106.730 131.011 1.00 84.78  ? 362 LEU B CB  1 
ATOM   4022  C CG  . LEU B 2 340 ? 180.209 107.534 131.924 1.00 84.78  ? 362 LEU B CG  1 
ATOM   4023  C CD1 . LEU B 2 340 ? 180.086 106.867 133.286 1.00 84.78  ? 362 LEU B CD1 1 
ATOM   4024  C CD2 . LEU B 2 340 ? 180.700 108.966 132.066 1.00 84.78  ? 362 LEU B CD2 1 
ATOM   4025  N N   . ASP B 2 341 ? 182.148 105.348 128.486 1.00 94.25  ? 363 ASP B N   1 
ATOM   4026  C CA  . ASP B 2 341 ? 183.074 104.465 127.789 1.00 94.25  ? 363 ASP B CA  1 
ATOM   4027  C C   . ASP B 2 341 ? 182.276 103.490 126.935 1.00 94.25  ? 363 ASP B C   1 
ATOM   4028  O O   . ASP B 2 341 ? 181.054 103.381 127.055 1.00 94.25  ? 363 ASP B O   1 
ATOM   4029  C CB  . ASP B 2 341 ? 183.980 103.719 128.774 1.00 94.25  ? 363 ASP B CB  1 
ATOM   4030  C CG  . ASP B 2 341 ? 183.210 103.125 129.936 1.00 94.25  ? 363 ASP B CG  1 
ATOM   4031  O OD1 . ASP B 2 341 ? 182.171 103.702 130.317 1.00 94.25  ? 363 ASP B OD1 1 
ATOM   4032  O OD2 . ASP B 2 341 ? 183.643 102.082 130.468 1.00 94.25  ? 363 ASP B OD2 1 
ATOM   4033  N N   . TYR B 2 342 ? 182.993 102.778 126.068 1.00 92.80  ? 364 TYR B N   1 
ATOM   4034  C CA  . TYR B 2 342 ? 182.406 101.804 125.158 1.00 92.80  ? 364 TYR B CA  1 
ATOM   4035  C C   . TYR B 2 342 ? 182.993 100.432 125.450 1.00 92.80  ? 364 TYR B C   1 
ATOM   4036  O O   . TYR B 2 342 ? 184.215 100.283 125.543 1.00 92.80  ? 364 TYR B O   1 
ATOM   4037  C CB  . TYR B 2 342 ? 182.658 102.192 123.697 1.00 92.80  ? 364 TYR B CB  1 
ATOM   4038  C CG  . TYR B 2 342 ? 182.234 103.603 123.356 1.00 92.80  ? 364 TYR B CG  1 
ATOM   4039  C CD1 . TYR B 2 342 ? 180.950 103.873 122.902 1.00 92.80  ? 364 TYR B CD1 1 
ATOM   4040  C CD2 . TYR B 2 342 ? 183.117 104.666 123.488 1.00 92.80  ? 364 TYR B CD2 1 
ATOM   4041  C CE1 . TYR B 2 342 ? 180.558 105.160 122.590 1.00 92.80  ? 364 TYR B CE1 1 
ATOM   4042  C CE2 . TYR B 2 342 ? 182.734 105.956 123.178 1.00 92.80  ? 364 TYR B CE2 1 
ATOM   4043  C CZ  . TYR B 2 342 ? 181.454 106.197 122.730 1.00 92.80  ? 364 TYR B CZ  1 
ATOM   4044  O OH  . TYR B 2 342 ? 181.070 107.481 122.421 1.00 92.80  ? 364 TYR B OH  1 
ATOM   4045  N N   . GLU B 2 343 ? 182.123 99.435  125.590 1.00 92.50  ? 365 GLU B N   1 
ATOM   4046  C CA  . GLU B 2 343 ? 182.521 98.076  125.928 1.00 92.50  ? 365 GLU B CA  1 
ATOM   4047  C C   . GLU B 2 343 ? 182.433 97.194  124.691 1.00 92.50  ? 365 GLU B C   1 
ATOM   4048  O O   . GLU B 2 343 ? 181.453 97.263  123.943 1.00 92.50  ? 365 GLU B O   1 
ATOM   4049  C CB  . GLU B 2 343 ? 181.640 97.508  127.042 1.00 92.50  ? 365 GLU B CB  1 
ATOM   4050  C CG  . GLU B 2 343 ? 181.879 98.130  128.408 1.00 92.50  ? 365 GLU B CG  1 
ATOM   4051  C CD  . GLU B 2 343 ? 181.215 99.484  128.559 1.00 92.50  ? 365 GLU B CD  1 
ATOM   4052  O OE1 . GLU B 2 343 ? 180.350 99.821  127.723 1.00 92.50  ? 365 GLU B OE1 1 
ATOM   4053  O OE2 . GLU B 2 343 ? 181.560 100.213 129.512 1.00 92.50  ? 365 GLU B OE2 1 
ATOM   4054  N N   . VAL B 2 344 ? 183.456 96.368  124.481 1.00 110.51 ? 366 VAL B N   1 
ATOM   4055  C CA  . VAL B 2 344 ? 183.490 95.433  123.365 1.00 110.51 ? 366 VAL B CA  1 
ATOM   4056  C C   . VAL B 2 344 ? 183.655 94.021  123.910 1.00 110.51 ? 366 VAL B C   1 
ATOM   4057  O O   . VAL B 2 344 ? 184.291 93.800  124.945 1.00 110.51 ? 366 VAL B O   1 
ATOM   4058  C CB  . VAL B 2 344 ? 184.612 95.770  122.355 1.00 110.51 ? 366 VAL B CB  1 
ATOM   4059  C CG1 . VAL B 2 344 ? 184.503 97.219  121.903 1.00 110.51 ? 366 VAL B CG1 1 
ATOM   4060  C CG2 . VAL B 2 344 ? 185.982 95.501  122.958 1.00 110.51 ? 366 VAL B CG2 1 
ATOM   4061  N N   . ILE B 2 345 ? 183.052 93.062  123.210 1.00 121.13 ? 367 ILE B N   1 
ATOM   4062  C CA  . ILE B 2 345 ? 183.109 91.652  123.581 1.00 121.13 ? 367 ILE B CA  1 
ATOM   4063  C C   . ILE B 2 345 ? 183.337 90.837  122.317 1.00 121.13 ? 367 ILE B C   1 
ATOM   4064  O O   . ILE B 2 345 ? 182.584 90.967  121.347 1.00 121.13 ? 367 ILE B O   1 
ATOM   4065  C CB  . ILE B 2 345 ? 181.823 91.180  124.293 1.00 121.13 ? 367 ILE B CB  1 
ATOM   4066  C CG1 . ILE B 2 345 ? 181.662 91.861  125.655 1.00 121.13 ? 367 ILE B CG1 1 
ATOM   4067  C CG2 . ILE B 2 345 ? 181.822 89.666  124.444 1.00 121.13 ? 367 ILE B CG2 1 
ATOM   4068  C CD1 . ILE B 2 345 ? 180.843 93.137  125.620 1.00 121.13 ? 367 ILE B CD1 1 
ATOM   4069  N N   . LEU B 2 346 ? 184.368 89.997  122.326 1.00 147.66 ? 368 LEU B N   1 
ATOM   4070  C CA  . LEU B 2 346 ? 184.701 89.153  121.187 1.00 147.66 ? 368 LEU B CA  1 
ATOM   4071  C C   . LEU B 2 346 ? 184.715 87.690  121.608 1.00 147.66 ? 368 LEU B C   1 
ATOM   4072  O O   . LEU B 2 346 ? 185.178 87.351  122.702 1.00 147.66 ? 368 LEU B O   1 
ATOM   4073  C CB  . LEU B 2 346 ? 186.056 89.547  120.581 1.00 147.66 ? 368 LEU B CB  1 
ATOM   4074  C CG  . LEU B 2 346 ? 187.304 89.494  121.467 1.00 147.66 ? 368 LEU B CG  1 
ATOM   4075  C CD1 . LEU B 2 346 ? 188.034 88.166  121.323 1.00 147.66 ? 368 LEU B CD1 1 
ATOM   4076  C CD2 . LEU B 2 346 ? 188.231 90.653  121.140 1.00 147.66 ? 368 LEU B CD2 1 
ATOM   4077  N N   . THR B 2 347 ? 184.201 86.829  120.731 1.00 174.09 ? 369 THR B N   1 
ATOM   4078  C CA  . THR B 2 347 ? 184.179 85.391  120.969 1.00 174.09 ? 369 THR B CA  1 
ATOM   4079  C C   . THR B 2 347 ? 183.931 84.687  119.645 1.00 174.09 ? 369 THR B C   1 
ATOM   4080  O O   . THR B 2 347 ? 183.091 85.130  118.855 1.00 174.09 ? 369 THR B O   1 
ATOM   4081  C CB  . THR B 2 347 ? 183.103 85.010  121.997 1.00 174.09 ? 369 THR B CB  1 
ATOM   4082  O OG1 . THR B 2 347 ? 182.988 83.583  122.068 1.00 174.09 ? 369 THR B OG1 1 
ATOM   4083  C CG2 . THR B 2 347 ? 181.754 85.615  121.628 1.00 174.09 ? 369 THR B CG2 1 
ATOM   4084  N N   . GLN B 2 348 ? 184.668 83.609  119.396 1.00 198.86 ? 370 GLN B N   1 
ATOM   4085  C CA  . GLN B 2 348 ? 184.527 82.865  118.144 1.00 198.86 ? 370 GLN B CA  1 
ATOM   4086  C C   . GLN B 2 348 ? 183.517 81.729  118.277 1.00 198.86 ? 370 GLN B C   1 
ATOM   4087  O O   . GLN B 2 348 ? 183.784 80.584  117.913 1.00 198.86 ? 370 GLN B O   1 
ATOM   4088  C CB  . GLN B 2 348 ? 185.887 82.339  117.700 1.00 198.86 ? 370 GLN B CB  1 
ATOM   4089  C CG  . GLN B 2 348 ? 187.045 83.276  118.004 1.00 198.86 ? 370 GLN B CG  1 
ATOM   4090  C CD  . GLN B 2 348 ? 187.705 82.976  119.336 1.00 198.86 ? 370 GLN B CD  1 
ATOM   4091  O OE1 . GLN B 2 348 ? 187.766 81.824  119.767 1.00 198.86 ? 370 GLN B OE1 1 
ATOM   4092  N NE2 . GLN B 2 348 ? 188.201 84.015  119.998 1.00 198.86 ? 370 GLN B NE2 1 
ATOM   4093  N N   . SER B 2 349 ? 182.345 82.055  118.827 1.00 213.07 ? 371 SER B N   1 
ATOM   4094  C CA  . SER B 2 349 ? 181.189 81.164  118.892 1.00 213.07 ? 371 SER B CA  1 
ATOM   4095  C C   . SER B 2 349 ? 181.431 79.941  119.772 1.00 213.07 ? 371 SER B C   1 
ATOM   4096  O O   . SER B 2 349 ? 180.509 79.151  120.003 1.00 213.07 ? 371 SER B O   1 
ATOM   4097  C CB  . SER B 2 349 ? 180.775 80.724  117.484 1.00 213.07 ? 371 SER B CB  1 
ATOM   4098  O OG  . SER B 2 349 ? 180.493 81.843  116.661 1.00 213.07 ? 371 SER B OG  1 
ATOM   4099  N N   . LYS B 2 350 ? 182.657 79.769  120.268 1.00 217.95 ? 372 LYS B N   1 
ATOM   4100  C CA  . LYS B 2 350 ? 182.981 78.614  121.102 1.00 217.95 ? 372 LYS B CA  1 
ATOM   4101  C C   . LYS B 2 350 ? 183.858 78.926  122.304 1.00 217.95 ? 372 LYS B C   1 
ATOM   4102  O O   . LYS B 2 350 ? 183.946 78.082  123.203 1.00 217.95 ? 372 LYS B O   1 
ATOM   4103  C CB  . LYS B 2 350 ? 183.668 77.529  120.263 1.00 217.95 ? 372 LYS B CB  1 
ATOM   4104  C CG  . LYS B 2 350 ? 184.965 77.981  119.611 1.00 217.95 ? 372 LYS B CG  1 
ATOM   4105  C CD  . LYS B 2 350 ? 185.578 76.874  118.769 1.00 217.95 ? 372 LYS B CD  1 
ATOM   4106  C CE  . LYS B 2 350 ? 186.886 77.322  118.137 1.00 217.95 ? 372 LYS B CE  1 
ATOM   4107  N NZ  . LYS B 2 350 ? 186.702 78.518  117.269 1.00 217.95 ? 372 LYS B NZ  1 
ATOM   4108  N N   . SER B 2 351 ? 184.507 80.083  122.371 1.00 212.32 ? 373 SER B N   1 
ATOM   4109  C CA  . SER B 2 351 ? 185.452 80.387  123.430 1.00 212.32 ? 373 SER B CA  1 
ATOM   4110  C C   . SER B 2 351 ? 184.816 81.324  124.456 1.00 212.32 ? 373 SER B C   1 
ATOM   4111  O O   . SER B 2 351 ? 183.625 81.644  124.391 1.00 212.32 ? 373 SER B O   1 
ATOM   4112  C CB  . SER B 2 351 ? 186.729 80.983  122.834 1.00 212.32 ? 373 SER B CB  1 
ATOM   4113  O OG  . SER B 2 351 ? 187.519 81.600  123.836 1.00 212.32 ? 373 SER B OG  1 
ATOM   4114  N N   . VAL B 2 352 ? 185.620 81.771  125.418 1.00 193.02 ? 374 VAL B N   1 
ATOM   4115  C CA  . VAL B 2 352 ? 185.159 82.683  126.459 1.00 193.02 ? 374 VAL B CA  1 
ATOM   4116  C C   . VAL B 2 352 ? 185.111 84.099  125.901 1.00 193.02 ? 374 VAL B C   1 
ATOM   4117  O O   . VAL B 2 352 ? 185.661 84.376  124.829 1.00 193.02 ? 374 VAL B O   1 
ATOM   4118  C CB  . VAL B 2 352 ? 186.061 82.610  127.704 1.00 193.02 ? 374 VAL B CB  1 
ATOM   4119  C CG1 . VAL B 2 352 ? 185.804 81.322  128.470 1.00 193.02 ? 374 VAL B CG1 1 
ATOM   4120  C CG2 . VAL B 2 352 ? 187.525 82.718  127.304 1.00 193.02 ? 374 VAL B CG2 1 
ATOM   4121  N N   . SER B 2 353 ? 184.455 85.002  126.624 1.00 161.58 ? 375 SER B N   1 
ATOM   4122  C CA  . SER B 2 353 ? 184.303 86.383  126.189 1.00 161.58 ? 375 SER B CA  1 
ATOM   4123  C C   . SER B 2 353 ? 185.475 87.221  126.681 1.00 161.58 ? 375 SER B C   1 
ATOM   4124  O O   . SER B 2 353 ? 185.791 87.220  127.875 1.00 161.58 ? 375 SER B O   1 
ATOM   4125  C CB  . SER B 2 353 ? 182.985 86.965  126.701 1.00 161.58 ? 375 SER B CB  1 
ATOM   4126  O OG  . SER B 2 353 ? 183.139 87.513  127.999 1.00 161.58 ? 375 SER B OG  1 
ATOM   4127  N N   . GLN B 2 354 ? 186.115 87.934  125.758 1.00 137.35 ? 376 GLN B N   1 
ATOM   4128  C CA  . GLN B 2 354 ? 187.213 88.839  126.077 1.00 137.35 ? 376 GLN B CA  1 
ATOM   4129  C C   . GLN B 2 354 ? 186.673 90.263  126.116 1.00 137.35 ? 376 GLN B C   1 
ATOM   4130  O O   . GLN B 2 354 ? 186.244 90.796  125.087 1.00 137.35 ? 376 GLN B O   1 
ATOM   4131  C CB  . GLN B 2 354 ? 188.338 88.715  125.050 1.00 137.35 ? 376 GLN B CB  1 
ATOM   4132  C CG  . GLN B 2 354 ? 189.659 89.315  125.499 1.00 137.35 ? 376 GLN B CG  1 
ATOM   4133  C CD  . GLN B 2 354 ? 190.408 88.421  126.466 1.00 137.35 ? 376 GLN B CD  1 
ATOM   4134  O OE1 . GLN B 2 354 ? 190.093 87.239  126.608 1.00 137.35 ? 376 GLN B OE1 1 
ATOM   4135  N NE2 . GLN B 2 354 ? 191.406 88.982  127.139 1.00 137.35 ? 376 GLN B NE2 1 
ATOM   4136  N N   . THR B 2 355 ? 186.696 90.874  127.296 1.00 121.21 ? 377 THR B N   1 
ATOM   4137  C CA  . THR B 2 355 ? 186.112 92.188  127.515 1.00 121.21 ? 377 THR B CA  1 
ATOM   4138  C C   . THR B 2 355 ? 187.201 93.251  127.569 1.00 121.21 ? 377 THR B C   1 
ATOM   4139  O O   . THR B 2 355 ? 188.247 93.052  128.194 1.00 121.21 ? 377 THR B O   1 
ATOM   4140  C CB  . THR B 2 355 ? 185.296 92.216  128.811 1.00 121.21 ? 377 THR B CB  1 
ATOM   4141  O OG1 . THR B 2 355 ? 184.406 91.093  128.842 1.00 121.21 ? 377 THR B OG1 1 
ATOM   4142  C CG2 . THR B 2 355 ? 184.483 93.499  128.905 1.00 121.21 ? 377 THR B CG2 1 
ATOM   4143  N N   . TYR B 2 356 ? 186.947 94.378  126.908 1.00 114.98 ? 378 TYR B N   1 
ATOM   4144  C CA  . TYR B 2 356 ? 187.834 95.530  126.935 1.00 114.98 ? 378 TYR B CA  1 
ATOM   4145  C C   . TYR B 2 356 ? 187.031 96.772  127.292 1.00 114.98 ? 378 TYR B C   1 
ATOM   4146  O O   . TYR B 2 356 ? 185.797 96.761  127.291 1.00 114.98 ? 378 TYR B O   1 
ATOM   4147  C CB  . TYR B 2 356 ? 188.543 95.737  125.589 1.00 114.98 ? 378 TYR B CB  1 
ATOM   4148  C CG  . TYR B 2 356 ? 189.382 94.563  125.141 1.00 114.98 ? 378 TYR B CG  1 
ATOM   4149  C CD1 . TYR B 2 356 ? 190.692 94.415  125.576 1.00 114.98 ? 378 TYR B CD1 1 
ATOM   4150  C CD2 . TYR B 2 356 ? 188.866 93.606  124.278 1.00 114.98 ? 378 TYR B CD2 1 
ATOM   4151  C CE1 . TYR B 2 356 ? 191.464 93.344  125.167 1.00 114.98 ? 378 TYR B CE1 1 
ATOM   4152  C CE2 . TYR B 2 356 ? 189.630 92.532  123.863 1.00 114.98 ? 378 TYR B CE2 1 
ATOM   4153  C CZ  . TYR B 2 356 ? 190.928 92.406  124.310 1.00 114.98 ? 378 TYR B CZ  1 
ATOM   4154  O OH  . TYR B 2 356 ? 191.693 91.339  123.900 1.00 114.98 ? 378 TYR B OH  1 
ATOM   4155  N N   . THR B 2 357 ? 187.747 97.849  127.603 1.00 107.73 ? 379 THR B N   1 
ATOM   4156  C CA  . THR B 2 357 ? 187.136 99.133  127.936 1.00 107.73 ? 379 THR B CA  1 
ATOM   4157  C C   . THR B 2 357 ? 187.943 100.237 127.268 1.00 107.73 ? 379 THR B C   1 
ATOM   4158  O O   . THR B 2 357 ? 189.078 100.512 127.670 1.00 107.73 ? 379 THR B O   1 
ATOM   4159  C CB  . THR B 2 357 ? 187.071 99.344  129.449 1.00 107.73 ? 379 THR B CB  1 
ATOM   4160  O OG1 . THR B 2 357 ? 186.201 98.365  130.031 1.00 107.73 ? 379 THR B OG1 1 
ATOM   4161  C CG2 . THR B 2 357 ? 186.546 100.734 129.768 1.00 107.73 ? 379 THR B CG2 1 
ATOM   4162  N N   . VAL B 2 358 ? 187.360 100.865 126.250 1.00 111.71 ? 380 VAL B N   1 
ATOM   4163  C CA  . VAL B 2 358 ? 188.003 101.939 125.502 1.00 111.71 ? 380 VAL B CA  1 
ATOM   4164  C C   . VAL B 2 358 ? 187.109 103.168 125.584 1.00 111.71 ? 380 VAL B C   1 
ATOM   4165  O O   . VAL B 2 358 ? 185.935 103.114 125.197 1.00 111.71 ? 380 VAL B O   1 
ATOM   4166  C CB  . VAL B 2 358 ? 188.259 101.547 124.039 1.00 111.71 ? 380 VAL B CB  1 
ATOM   4167  C CG1 . VAL B 2 358 ? 188.886 102.706 123.281 1.00 111.71 ? 380 VAL B CG1 1 
ATOM   4168  C CG2 . VAL B 2 358 ? 189.145 100.314 123.966 1.00 111.71 ? 380 VAL B CG2 1 
ATOM   4169  N N   . THR B 2 359 ? 187.662 104.272 126.085 1.00 108.04 ? 381 THR B N   1 
ATOM   4170  C CA  . THR B 2 359 ? 186.919 105.522 126.167 1.00 108.04 ? 381 THR B CA  1 
ATOM   4171  C C   . THR B 2 359 ? 186.953 106.316 124.869 1.00 108.04 ? 381 THR B C   1 
ATOM   4172  O O   . THR B 2 359 ? 186.214 107.298 124.744 1.00 108.04 ? 381 THR B O   1 
ATOM   4173  C CB  . THR B 2 359 ? 187.461 106.390 127.306 1.00 108.04 ? 381 THR B CB  1 
ATOM   4174  O OG1 . THR B 2 359 ? 186.616 107.534 127.480 1.00 108.04 ? 381 THR B OG1 1 
ATOM   4175  C CG2 . THR B 2 359 ? 188.876 106.854 126.993 1.00 108.04 ? 381 THR B CG2 1 
ATOM   4176  N N   . GLY B 2 360 ? 187.786 105.922 123.912 1.00 107.45 ? 382 GLY B N   1 
ATOM   4177  C CA  . GLY B 2 360 ? 187.880 106.594 122.635 1.00 107.45 ? 382 GLY B CA  1 
ATOM   4178  C C   . GLY B 2 360 ? 186.844 106.101 121.647 1.00 107.45 ? 382 GLY B C   1 
ATOM   4179  O O   . GLY B 2 360 ? 185.812 105.533 122.014 1.00 107.45 ? 382 GLY B O   1 
ATOM   4180  N N   . THR B 2 361 ? 187.132 106.325 120.367 1.00 107.97 ? 383 THR B N   1 
ATOM   4181  C CA  . THR B 2 361 ? 186.235 105.935 119.289 1.00 107.97 ? 383 THR B CA  1 
ATOM   4182  C C   . THR B 2 361 ? 186.805 104.835 118.406 1.00 107.97 ? 383 THR B C   1 
ATOM   4183  O O   . THR B 2 361 ? 186.116 104.381 117.487 1.00 107.97 ? 383 THR B O   1 
ATOM   4184  C CB  . THR B 2 361 ? 185.883 107.153 118.426 1.00 107.97 ? 383 THR B CB  1 
ATOM   4185  O OG1 . THR B 2 361 ? 187.077 107.687 117.841 1.00 107.97 ? 383 THR B OG1 1 
ATOM   4186  C CG2 . THR B 2 361 ? 185.214 108.227 119.270 1.00 107.97 ? 383 THR B CG2 1 
ATOM   4187  N N   . GLU B 2 362 ? 188.035 104.393 118.655 1.00 111.36 ? 384 GLU B N   1 
ATOM   4188  C CA  . GLU B 2 362 ? 188.664 103.365 117.841 1.00 111.36 ? 384 GLU B CA  1 
ATOM   4189  C C   . GLU B 2 362 ? 189.327 102.336 118.745 1.00 111.36 ? 384 GLU B C   1 
ATOM   4190  O O   . GLU B 2 362 ? 189.598 102.592 119.921 1.00 111.36 ? 384 GLU B O   1 
ATOM   4191  C CB  . GLU B 2 362 ? 189.697 103.961 116.875 1.00 111.36 ? 384 GLU B CB  1 
ATOM   4192  C CG  . GLU B 2 362 ? 189.116 104.438 115.555 1.00 111.36 ? 384 GLU B CG  1 
ATOM   4193  C CD  . GLU B 2 362 ? 188.426 105.782 115.671 1.00 111.36 ? 384 GLU B CD  1 
ATOM   4194  O OE1 . GLU B 2 362 ? 188.717 106.521 116.635 1.00 111.36 ? 384 GLU B OE1 1 
ATOM   4195  O OE2 . GLU B 2 362 ? 187.593 106.101 114.797 1.00 111.36 ? 384 GLU B OE2 1 
ATOM   4196  N N   . LEU B 2 363 ? 189.584 101.159 118.176 1.00 130.97 ? 385 LEU B N   1 
ATOM   4197  C CA  . LEU B 2 363 ? 190.249 100.082 118.898 1.00 130.97 ? 385 LEU B CA  1 
ATOM   4198  C C   . LEU B 2 363 ? 190.840 99.113  117.887 1.00 130.97 ? 385 LEU B C   1 
ATOM   4199  O O   . LEU B 2 363 ? 190.149 98.691  116.955 1.00 130.97 ? 385 LEU B O   1 
ATOM   4200  C CB  . LEU B 2 363 ? 189.276 99.355  119.833 1.00 130.97 ? 385 LEU B CB  1 
ATOM   4201  C CG  . LEU B 2 363 ? 189.823 98.115  120.541 1.00 130.97 ? 385 LEU B CG  1 
ATOM   4202  C CD1 . LEU B 2 363 ? 191.071 98.454  121.341 1.00 130.97 ? 385 LEU B CD1 1 
ATOM   4203  C CD2 . LEU B 2 363 ? 188.760 97.502  121.437 1.00 130.97 ? 385 LEU B CD2 1 
ATOM   4204  N N   . THR B 2 364 ? 192.111 98.764  118.074 1.00 159.14 ? 386 THR B N   1 
ATOM   4205  C CA  . THR B 2 364 ? 192.828 97.866  117.176 1.00 159.14 ? 386 THR B CA  1 
ATOM   4206  C C   . THR B 2 364 ? 193.296 96.650  117.963 1.00 159.14 ? 386 THR B C   1 
ATOM   4207  O O   . THR B 2 364 ? 194.058 96.786  118.925 1.00 159.14 ? 386 THR B O   1 
ATOM   4208  C CB  . THR B 2 364 ? 194.020 98.572  116.525 1.00 159.14 ? 386 THR B CB  1 
ATOM   4209  O OG1 . THR B 2 364 ? 193.629 99.884  116.103 1.00 159.14 ? 386 THR B OG1 1 
ATOM   4210  C CG2 . THR B 2 364 ? 194.514 97.782  115.322 1.00 159.14 ? 386 THR B CG2 1 
ATOM   4211  N N   . VAL B 2 365 ? 192.837 95.466  117.554 1.00 185.60 ? 387 VAL B N   1 
ATOM   4212  C CA  . VAL B 2 365 ? 193.227 94.210  118.177 1.00 185.60 ? 387 VAL B CA  1 
ATOM   4213  C C   . VAL B 2 365 ? 193.635 93.229  117.086 1.00 185.60 ? 387 VAL B C   1 
ATOM   4214  O O   . VAL B 2 365 ? 193.184 93.311  115.942 1.00 185.60 ? 387 VAL B O   1 
ATOM   4215  C CB  . VAL B 2 365 ? 192.100 93.611  119.049 1.00 185.60 ? 387 VAL B CB  1 
ATOM   4216  C CG1 . VAL B 2 365 ? 191.811 94.513  120.239 1.00 185.60 ? 387 VAL B CG1 1 
ATOM   4217  C CG2 . VAL B 2 365 ? 190.844 93.396  118.220 1.00 185.60 ? 387 VAL B CG2 1 
ATOM   4218  N N   . ASN B 2 366 ? 194.509 92.295  117.456 1.00 209.98 ? 388 ASN B N   1 
ATOM   4219  C CA  . ASN B 2 366 ? 195.000 91.271  116.539 1.00 209.98 ? 388 ASN B CA  1 
ATOM   4220  C C   . ASN B 2 366 ? 194.169 90.002  116.702 1.00 209.98 ? 388 ASN B C   1 
ATOM   4221  O O   . ASN B 2 366 ? 194.172 89.375  117.767 1.00 209.98 ? 388 ASN B O   1 
ATOM   4222  C CB  . ASN B 2 366 ? 196.490 91.006  116.757 1.00 209.98 ? 388 ASN B CB  1 
ATOM   4223  C CG  . ASN B 2 366 ? 196.841 90.740  118.214 1.00 209.98 ? 388 ASN B CG  1 
ATOM   4224  O OD1 . ASN B 2 366 ? 195.979 90.764  119.091 1.00 209.98 ? 388 ASN B OD1 1 
ATOM   4225  N ND2 . ASN B 2 366 ? 198.119 90.481  118.474 1.00 209.98 ? 388 ASN B ND2 1 
ATOM   4226  N N   . LEU B 2 367 ? 193.451 89.633  115.648 1.00 208.60 ? 389 LEU B N   1 
ATOM   4227  C CA  . LEU B 2 367 ? 192.627 88.436  115.628 1.00 208.60 ? 389 LEU B CA  1 
ATOM   4228  C C   . LEU B 2 367 ? 193.194 87.429  114.637 1.00 208.60 ? 389 LEU B C   1 
ATOM   4229  O O   . LEU B 2 367 ? 193.954 87.776  113.730 1.00 208.60 ? 389 LEU B O   1 
ATOM   4230  C CB  . LEU B 2 367 ? 191.178 88.774  115.261 1.00 208.60 ? 389 LEU B CB  1 
ATOM   4231  C CG  . LEU B 2 367 ? 190.540 89.918  116.047 1.00 208.60 ? 389 LEU B CG  1 
ATOM   4232  C CD1 . LEU B 2 367 ? 189.086 90.100  115.646 1.00 208.60 ? 389 LEU B CD1 1 
ATOM   4233  C CD2 . LEU B 2 367 ? 190.660 89.664  117.538 1.00 208.60 ? 389 LEU B CD2 1 
ATOM   4234  N N   . THR B 2 368 ? 192.813 86.169  114.823 1.00 219.66 ? 390 THR B N   1 
ATOM   4235  C CA  . THR B 2 368 ? 193.247 85.100  113.937 1.00 219.66 ? 390 THR B CA  1 
ATOM   4236  C C   . THR B 2 368 ? 192.255 84.964  112.779 1.00 219.66 ? 390 THR B C   1 
ATOM   4237  O O   . THR B 2 368 ? 191.356 85.790  112.601 1.00 219.66 ? 390 THR B O   1 
ATOM   4238  C CB  . THR B 2 368 ? 193.424 83.802  114.725 1.00 219.66 ? 390 THR B CB  1 
ATOM   4239  O OG1 . THR B 2 368 ? 194.146 82.851  113.932 1.00 219.66 ? 390 THR B OG1 1 
ATOM   4240  C CG2 . THR B 2 368 ? 192.081 83.219  115.127 1.00 219.66 ? 390 THR B CG2 1 
ATOM   4241  N N   . ASN B 2 369 ? 192.410 83.912  111.974 1.00 222.67 ? 391 ASN B N   1 
ATOM   4242  C CA  . ASN B 2 369 ? 191.683 83.797  110.716 1.00 222.67 ? 391 ASN B CA  1 
ATOM   4243  C C   . ASN B 2 369 ? 190.266 83.255  110.868 1.00 222.67 ? 391 ASN B C   1 
ATOM   4244  O O   . ASN B 2 369 ? 189.516 83.266  109.887 1.00 222.67 ? 391 ASN B O   1 
ATOM   4245  C CB  . ASN B 2 369 ? 192.460 82.904  109.744 1.00 222.67 ? 391 ASN B CB  1 
ATOM   4246  C CG  . ASN B 2 369 ? 192.349 81.433  110.090 1.00 222.67 ? 391 ASN B CG  1 
ATOM   4247  O OD1 . ASN B 2 369 ? 193.032 80.941  110.988 1.00 222.67 ? 391 ASN B OD1 1 
ATOM   4248  N ND2 . ASN B 2 369 ? 191.487 80.719  109.375 1.00 222.67 ? 391 ASN B ND2 1 
ATOM   4249  N N   . ASP B 2 370 ? 189.877 82.784  112.050 1.00 213.73 ? 392 ASP B N   1 
ATOM   4250  C CA  . ASP B 2 370 ? 188.554 82.201  112.208 1.00 213.73 ? 392 ASP B CA  1 
ATOM   4251  C C   . ASP B 2 370 ? 187.494 83.300  112.295 1.00 213.73 ? 392 ASP B C   1 
ATOM   4252  O O   . ASP B 2 370 ? 187.797 84.497  112.325 1.00 213.73 ? 392 ASP B O   1 
ATOM   4253  C CB  . ASP B 2 370 ? 188.516 81.281  113.429 1.00 213.73 ? 392 ASP B CB  1 
ATOM   4254  C CG  . ASP B 2 370 ? 188.702 82.025  114.741 1.00 213.73 ? 392 ASP B CG  1 
ATOM   4255  O OD1 . ASP B 2 370 ? 188.990 83.239  114.718 1.00 213.73 ? 392 ASP B OD1 1 
ATOM   4256  O OD2 . ASP B 2 370 ? 188.561 81.386  115.804 1.00 213.73 ? 392 ASP B OD2 1 
ATOM   4257  N N   . ARG B 2 371 ? 186.230 82.888  112.337 1.00 195.18 ? 393 ARG B N   1 
ATOM   4258  C CA  . ARG B 2 371 ? 185.126 83.833  112.408 1.00 195.18 ? 393 ARG B CA  1 
ATOM   4259  C C   . ARG B 2 371 ? 184.943 84.337  113.834 1.00 195.18 ? 393 ARG B C   1 
ATOM   4260  O O   . ARG B 2 371 ? 185.008 83.567  114.796 1.00 195.18 ? 393 ARG B O   1 
ATOM   4261  C CB  . ARG B 2 371 ? 183.835 83.183  111.911 1.00 195.18 ? 393 ARG B CB  1 
ATOM   4262  C CG  . ARG B 2 371 ? 182.674 84.150  111.754 1.00 195.18 ? 393 ARG B CG  1 
ATOM   4263  C CD  . ARG B 2 371 ? 181.445 83.449  111.200 1.00 195.18 ? 393 ARG B CD  1 
ATOM   4264  N NE  . ARG B 2 371 ? 180.922 82.450  112.128 1.00 195.18 ? 393 ARG B NE  1 
ATOM   4265  C CZ  . ARG B 2 371 ? 179.955 82.682  113.010 1.00 195.18 ? 393 ARG B CZ  1 
ATOM   4266  N NH1 . ARG B 2 371 ? 179.399 83.884  113.087 1.00 195.18 ? 393 ARG B NH1 1 
ATOM   4267  N NH2 . ARG B 2 371 ? 179.542 81.713  113.815 1.00 195.18 ? 393 ARG B NH2 1 
ATOM   4268  N N   . TYR B 2 372 ? 184.713 85.640  113.964 1.00 184.53 ? 394 TYR B N   1 
ATOM   4269  C CA  . TYR B 2 372 ? 184.504 86.285  115.250 1.00 184.53 ? 394 TYR B CA  1 
ATOM   4270  C C   . TYR B 2 372 ? 183.086 86.832  115.341 1.00 184.53 ? 394 TYR B C   1 
ATOM   4271  O O   . TYR B 2 372 ? 182.439 87.118  114.331 1.00 184.53 ? 394 TYR B O   1 
ATOM   4272  C CB  . TYR B 2 372 ? 185.512 87.419  115.468 1.00 184.53 ? 394 TYR B CB  1 
ATOM   4273  C CG  . TYR B 2 372 ? 186.812 86.980  116.102 1.00 184.53 ? 394 TYR B CG  1 
ATOM   4274  C CD1 . TYR B 2 372 ? 187.020 87.113  117.468 1.00 184.53 ? 394 TYR B CD1 1 
ATOM   4275  C CD2 . TYR B 2 372 ? 187.834 86.440  115.333 1.00 184.53 ? 394 TYR B CD2 1 
ATOM   4276  C CE1 . TYR B 2 372 ? 188.208 86.715  118.052 1.00 184.53 ? 394 TYR B CE1 1 
ATOM   4277  C CE2 . TYR B 2 372 ? 189.025 86.042  115.908 1.00 184.53 ? 394 TYR B CE2 1 
ATOM   4278  C CZ  . TYR B 2 372 ? 189.207 86.180  117.267 1.00 184.53 ? 394 TYR B CZ  1 
ATOM   4279  O OH  . TYR B 2 372 ? 190.392 85.784  117.842 1.00 184.53 ? 394 TYR B OH  1 
ATOM   4280  N N   . VAL B 2 373 ? 182.608 86.974  116.575 1.00 153.29 ? 395 VAL B N   1 
ATOM   4281  C CA  . VAL B 2 373 ? 181.293 87.540  116.863 1.00 153.29 ? 395 VAL B CA  1 
ATOM   4282  C C   . VAL B 2 373 ? 181.512 88.660  117.872 1.00 153.29 ? 395 VAL B C   1 
ATOM   4283  O O   . VAL B 2 373 ? 181.739 88.401  119.059 1.00 153.29 ? 395 VAL B O   1 
ATOM   4284  C CB  . VAL B 2 373 ? 180.306 86.497  117.399 1.00 153.29 ? 395 VAL B CB  1 
ATOM   4285  C CG1 . VAL B 2 373 ? 178.979 87.155  117.743 1.00 153.29 ? 395 VAL B CG1 1 
ATOM   4286  C CG2 . VAL B 2 373 ? 180.105 85.383  116.382 1.00 153.29 ? 395 VAL B CG2 1 
ATOM   4287  N N   . ALA B 2 374 ? 181.444 89.903  117.409 1.00 128.83 ? 396 ALA B N   1 
ATOM   4288  C CA  . ALA B 2 374 ? 181.677 91.068  118.248 1.00 128.83 ? 396 ALA B CA  1 
ATOM   4289  C C   . ALA B 2 374 ? 180.360 91.634  118.767 1.00 128.83 ? 396 ALA B C   1 
ATOM   4290  O O   . ALA B 2 374 ? 179.277 91.325  118.263 1.00 128.83 ? 396 ALA B O   1 
ATOM   4291  C CB  . ALA B 2 374 ? 182.442 92.147  117.476 1.00 128.83 ? 396 ALA B CB  1 
ATOM   4292  N N   . SER B 2 375 ? 180.470 92.471  119.797 1.00 107.45 ? 397 SER B N   1 
ATOM   4293  C CA  . SER B 2 375 ? 179.312 93.127  120.391 1.00 107.45 ? 397 SER B CA  1 
ATOM   4294  C C   . SER B 2 375 ? 179.760 94.443  121.006 1.00 107.45 ? 397 SER B C   1 
ATOM   4295  O O   . SER B 2 375 ? 180.764 94.483  121.723 1.00 107.45 ? 397 SER B O   1 
ATOM   4296  C CB  . SER B 2 375 ? 178.652 92.241  121.455 1.00 107.45 ? 397 SER B CB  1 
ATOM   4297  O OG  . SER B 2 375 ? 178.509 90.907  120.999 1.00 107.45 ? 397 SER B OG  1 
ATOM   4298  N N   . LEU B 2 376 ? 179.018 95.511  120.724 1.00 98.38  ? 398 LEU B N   1 
ATOM   4299  C CA  . LEU B 2 376 ? 179.335 96.841  121.224 1.00 98.38  ? 398 LEU B CA  1 
ATOM   4300  C C   . LEU B 2 376 ? 178.086 97.469  121.822 1.00 98.38  ? 398 LEU B C   1 
ATOM   4301  O O   . LEU B 2 376 ? 176.984 97.309  121.290 1.00 98.38  ? 398 LEU B O   1 
ATOM   4302  C CB  . LEU B 2 376 ? 179.904 97.732  120.105 1.00 98.38  ? 398 LEU B CB  1 
ATOM   4303  C CG  . LEU B 2 376 ? 180.126 99.220  120.388 1.00 98.38  ? 398 LEU B CG  1 
ATOM   4304  C CD1 . LEU B 2 376 ? 181.428 99.688  119.758 1.00 98.38  ? 398 LEU B CD1 1 
ATOM   4305  C CD2 . LEU B 2 376 ? 178.963 100.056 119.872 1.00 98.38  ? 398 LEU B CD2 1 
ATOM   4306  N N   . ALA B 2 377 ? 178.265 98.184  122.931 1.00 83.40  ? 399 ALA B N   1 
ATOM   4307  C CA  . ALA B 2 377 ? 177.160 98.850  123.606 1.00 83.40  ? 399 ALA B CA  1 
ATOM   4308  C C   . ALA B 2 377 ? 177.709 99.997  124.438 1.00 83.40  ? 399 ALA B C   1 
ATOM   4309  O O   . ALA B 2 377 ? 178.617 99.795  125.250 1.00 83.40  ? 399 ALA B O   1 
ATOM   4310  C CB  . ALA B 2 377 ? 176.381 97.873  124.493 1.00 83.40  ? 399 ALA B CB  1 
ATOM   4311  N N   . ALA B 2 378 ? 177.160 101.190 124.234 1.00 82.92  ? 400 ALA B N   1 
ATOM   4312  C CA  . ALA B 2 378 ? 177.604 102.354 124.989 1.00 82.92  ? 400 ALA B CA  1 
ATOM   4313  C C   . ALA B 2 378 ? 177.100 102.284 126.424 1.00 82.92  ? 400 ALA B C   1 
ATOM   4314  O O   . ALA B 2 378 ? 175.960 101.890 126.683 1.00 82.92  ? 400 ALA B O   1 
ATOM   4315  C CB  . ALA B 2 378 ? 177.115 103.638 124.322 1.00 82.92  ? 400 ALA B CB  1 
ATOM   4316  N N   . ARG B 2 379 ? 177.960 102.669 127.362 1.00 82.62  ? 401 ARG B N   1 
ATOM   4317  C CA  . ARG B 2 379 ? 177.626 102.663 128.779 1.00 82.62  ? 401 ARG B CA  1 
ATOM   4318  C C   . ARG B 2 379 ? 177.370 104.083 129.263 1.00 82.62  ? 401 ARG B C   1 
ATOM   4319  O O   . ARG B 2 379 ? 178.105 105.012 128.914 1.00 82.62  ? 401 ARG B O   1 
ATOM   4320  C CB  . ARG B 2 379 ? 178.746 102.024 129.603 1.00 82.62  ? 401 ARG B CB  1 
ATOM   4321  C CG  . ARG B 2 379 ? 178.380 101.780 131.060 1.00 82.62  ? 401 ARG B CG  1 
ATOM   4322  C CD  . ARG B 2 379 ? 179.554 101.213 131.842 1.00 82.62  ? 401 ARG B CD  1 
ATOM   4323  N NE  . ARG B 2 379 ? 180.633 102.184 131.993 1.00 82.62  ? 401 ARG B NE  1 
ATOM   4324  C CZ  . ARG B 2 379 ? 180.749 103.017 133.022 1.00 82.62  ? 401 ARG B CZ  1 
ATOM   4325  N NH1 . ARG B 2 379 ? 181.764 103.868 133.076 1.00 82.62  ? 401 ARG B NH1 1 
ATOM   4326  N NH2 . ARG B 2 379 ? 179.851 103.000 133.997 1.00 82.62  ? 401 ARG B NH2 1 
ATOM   4327  N N   . ASN B 2 380 ? 176.326 104.245 130.065 1.00 78.40  ? 402 ASN B N   1 
ATOM   4328  C CA  . ASN B 2 380 ? 175.942 105.530 130.629 1.00 78.40  ? 402 ASN B CA  1 
ATOM   4329  C C   . ASN B 2 380 ? 176.003 105.457 132.153 1.00 78.40  ? 402 ASN B C   1 
ATOM   4330  O O   . ASN B 2 380 ? 176.422 104.454 132.735 1.00 78.40  ? 402 ASN B O   1 
ATOM   4331  C CB  . ASN B 2 380 ? 174.546 105.939 130.151 1.00 78.40  ? 402 ASN B CB  1 
ATOM   4332  C CG  . ASN B 2 380 ? 174.337 107.440 130.175 1.00 78.40  ? 402 ASN B CG  1 
ATOM   4333  O OD1 . ASN B 2 380 ? 175.296 108.211 130.182 1.00 78.40  ? 402 ASN B OD1 1 
ATOM   4334  N ND2 . ASN B 2 380 ? 173.078 107.863 130.191 1.00 78.40  ? 402 ASN B ND2 1 
ATOM   4335  N N   . LYS B 2 381 ? 175.575 106.544 132.797 1.00 86.69  ? 403 LYS B N   1 
ATOM   4336  C CA  . LYS B 2 381 ? 175.599 106.603 134.255 1.00 86.69  ? 403 LYS B CA  1 
ATOM   4337  C C   . LYS B 2 381 ? 174.600 105.630 134.869 1.00 86.69  ? 403 LYS B C   1 
ATOM   4338  O O   . LYS B 2 381 ? 174.881 105.015 135.904 1.00 86.69  ? 403 LYS B O   1 
ATOM   4339  C CB  . LYS B 2 381 ? 175.318 108.032 134.719 1.00 86.69  ? 403 LYS B CB  1 
ATOM   4340  C CG  . LYS B 2 381 ? 175.160 108.192 136.221 1.00 86.69  ? 403 LYS B CG  1 
ATOM   4341  C CD  . LYS B 2 381 ? 174.720 109.603 136.572 1.00 86.69  ? 403 LYS B CD  1 
ATOM   4342  C CE  . LYS B 2 381 ? 174.469 109.753 138.062 1.00 86.69  ? 403 LYS B CE  1 
ATOM   4343  N NZ  . LYS B 2 381 ? 174.006 111.126 138.407 1.00 86.69  ? 403 LYS B NZ  1 
ATOM   4344  N N   . VAL B 2 382 ? 173.435 105.469 134.243 1.00 86.35  ? 404 VAL B N   1 
ATOM   4345  C CA  . VAL B 2 382 ? 172.386 104.617 134.793 1.00 86.35  ? 404 VAL B CA  1 
ATOM   4346  C C   . VAL B 2 382 ? 172.402 103.200 134.226 1.00 86.35  ? 404 VAL B C   1 
ATOM   4347  O O   . VAL B 2 382 ? 171.877 102.283 134.877 1.00 86.35  ? 404 VAL B O   1 
ATOM   4348  C CB  . VAL B 2 382 ? 170.997 105.253 134.579 1.00 86.35  ? 404 VAL B CB  1 
ATOM   4349  C CG1 . VAL B 2 382 ? 170.902 106.579 135.317 1.00 86.35  ? 404 VAL B CG1 1 
ATOM   4350  C CG2 . VAL B 2 382 ? 170.722 105.440 133.097 1.00 86.35  ? 404 VAL B CG2 1 
ATOM   4351  N N   . GLY B 2 383 ? 172.978 102.991 133.049 1.00 84.25  ? 405 GLY B N   1 
ATOM   4352  C CA  . GLY B 2 383 ? 173.011 101.659 132.479 1.00 84.25  ? 405 GLY B CA  1 
ATOM   4353  C C   . GLY B 2 383 ? 173.727 101.655 131.148 1.00 84.25  ? 405 GLY B C   1 
ATOM   4354  O O   . GLY B 2 383 ? 174.335 102.648 130.743 1.00 84.25  ? 405 GLY B O   1 
ATOM   4355  N N   . LYS B 2 384 ? 173.646 100.514 130.472 1.00 86.95  ? 406 LYS B N   1 
ATOM   4356  C CA  . LYS B 2 384 ? 174.262 100.327 129.168 1.00 86.95  ? 406 LYS B CA  1 
ATOM   4357  C C   . LYS B 2 384 ? 173.216 100.435 128.063 1.00 86.95  ? 406 LYS B C   1 
ATOM   4358  O O   . LYS B 2 384 ? 172.009 100.460 128.308 1.00 86.95  ? 406 LYS B O   1 
ATOM   4359  C CB  . LYS B 2 384 ? 174.975 98.973  129.098 1.00 86.95  ? 406 LYS B CB  1 
ATOM   4360  C CG  . LYS B 2 384 ? 176.213 98.877  129.974 1.00 86.95  ? 406 LYS B CG  1 
ATOM   4361  C CD  . LYS B 2 384 ? 176.962 97.579  129.723 1.00 86.95  ? 406 LYS B CD  1 
ATOM   4362  C CE  . LYS B 2 384 ? 178.251 97.522  130.526 1.00 86.95  ? 406 LYS B CE  1 
ATOM   4363  N NZ  . LYS B 2 384 ? 179.007 96.265  130.269 1.00 86.95  ? 406 LYS B NZ  1 
ATOM   4364  N N   . SER B 2 385 ? 173.703 100.499 126.827 1.00 88.37  ? 407 SER B N   1 
ATOM   4365  C CA  . SER B 2 385 ? 172.842 100.612 125.661 1.00 88.37  ? 407 SER B CA  1 
ATOM   4366  C C   . SER B 2 385 ? 172.527 99.219  125.116 1.00 88.37  ? 407 SER B C   1 
ATOM   4367  O O   . SER B 2 385 ? 172.824 98.199  125.743 1.00 88.37  ? 407 SER B O   1 
ATOM   4368  C CB  . SER B 2 385 ? 173.501 101.497 124.605 1.00 88.37  ? 407 SER B CB  1 
ATOM   4369  O OG  . SER B 2 385 ? 173.579 102.840 125.045 1.00 88.37  ? 407 SER B OG  1 
ATOM   4370  N N   . ALA B 2 386 ? 171.917 99.166  123.936 1.00 94.35  ? 408 ALA B N   1 
ATOM   4371  C CA  . ALA B 2 386 ? 171.628 97.890  123.302 1.00 94.35  ? 408 ALA B CA  1 
ATOM   4372  C C   . ALA B 2 386 ? 172.900 97.282  122.723 1.00 94.35  ? 408 ALA B C   1 
ATOM   4373  O O   . ALA B 2 386 ? 173.844 97.987  122.357 1.00 94.35  ? 408 ALA B O   1 
ATOM   4374  C CB  . ALA B 2 386 ? 170.580 98.062  122.203 1.00 94.35  ? 408 ALA B CB  1 
ATOM   4375  N N   . ALA B 2 387 ? 172.916 95.954  122.639 1.00 100.47 ? 409 ALA B N   1 
ATOM   4376  C CA  . ALA B 2 387 ? 174.083 95.217  122.161 1.00 100.47 ? 409 ALA B CA  1 
ATOM   4377  C C   . ALA B 2 387 ? 173.960 95.030  120.654 1.00 100.47 ? 409 ALA B C   1 
ATOM   4378  O O   . ALA B 2 387 ? 173.213 94.172  120.180 1.00 100.47 ? 409 ALA B O   1 
ATOM   4379  C CB  . ALA B 2 387 ? 174.207 93.879  122.881 1.00 100.47 ? 409 ALA B CB  1 
ATOM   4380  N N   . ALA B 2 388 ? 174.698 95.837  119.897 1.00 95.73  ? 410 ALA B N   1 
ATOM   4381  C CA  . ALA B 2 388 ? 174.743 95.713  118.447 1.00 95.73  ? 410 ALA B CA  1 
ATOM   4382  C C   . ALA B 2 388 ? 175.795 94.683  118.059 1.00 95.73  ? 410 ALA B C   1 
ATOM   4383  O O   . ALA B 2 388 ? 176.946 94.765  118.501 1.00 95.73  ? 410 ALA B O   1 
ATOM   4384  C CB  . ALA B 2 388 ? 175.050 97.062  117.796 1.00 95.73  ? 410 ALA B CB  1 
ATOM   4385  N N   . VAL B 2 389 ? 175.400 93.717  117.236 1.00 100.06 ? 411 VAL B N   1 
ATOM   4386  C CA  . VAL B 2 389 ? 176.268 92.616  116.837 1.00 100.06 ? 411 VAL B CA  1 
ATOM   4387  C C   . VAL B 2 389 ? 176.830 92.899  115.452 1.00 100.06 ? 411 VAL B C   1 
ATOM   4388  O O   . VAL B 2 389 ? 176.119 93.386  114.563 1.00 100.06 ? 411 VAL B O   1 
ATOM   4389  C CB  . VAL B 2 389 ? 175.509 91.274  116.871 1.00 100.06 ? 411 VAL B CB  1 
ATOM   4390  C CG1 . VAL B 2 389 ? 174.236 91.353  116.039 1.00 100.06 ? 411 VAL B CG1 1 
ATOM   4391  C CG2 . VAL B 2 389 ? 176.400 90.135  116.393 1.00 100.06 ? 411 VAL B CG2 1 
ATOM   4392  N N   . LEU B 2 390 ? 178.119 92.605  115.270 1.00 127.00 ? 412 LEU B N   1 
ATOM   4393  C CA  . LEU B 2 390 ? 178.773 92.760  113.971 1.00 127.00 ? 412 LEU B CA  1 
ATOM   4394  C C   . LEU B 2 390 ? 179.883 91.716  113.896 1.00 127.00 ? 412 LEU B C   1 
ATOM   4395  O O   . LEU B 2 390 ? 180.954 91.902  114.481 1.00 127.00 ? 412 LEU B O   1 
ATOM   4396  C CB  . LEU B 2 390 ? 179.314 94.170  113.785 1.00 127.00 ? 412 LEU B CB  1 
ATOM   4397  C CG  . LEU B 2 390 ? 179.560 94.598  112.336 1.00 127.00 ? 412 LEU B CG  1 
ATOM   4398  C CD1 . LEU B 2 390 ? 178.243 94.848  111.618 1.00 127.00 ? 412 LEU B CD1 1 
ATOM   4399  C CD2 . LEU B 2 390 ? 180.447 95.831  112.282 1.00 127.00 ? 412 LEU B CD2 1 
ATOM   4400  N N   . THR B 2 391 ? 179.621 90.630  113.175 1.00 155.80 ? 413 THR B N   1 
ATOM   4401  C CA  . THR B 2 391 ? 180.570 89.535  113.081 1.00 155.80 ? 413 THR B CA  1 
ATOM   4402  C C   . THR B 2 391 ? 181.684 89.862  112.091 1.00 155.80 ? 413 THR B C   1 
ATOM   4403  O O   . THR B 2 391 ? 181.563 90.752  111.245 1.00 155.80 ? 413 THR B O   1 
ATOM   4404  C CB  . THR B 2 391 ? 179.867 88.245  112.657 1.00 155.80 ? 413 THR B CB  1 
ATOM   4405  O OG1 . THR B 2 391 ? 180.830 87.191  112.540 1.00 155.80 ? 413 THR B OG1 1 
ATOM   4406  C CG2 . THR B 2 391 ? 179.169 88.436  111.318 1.00 155.80 ? 413 THR B CG2 1 
ATOM   4407  N N   . ILE B 2 392 ? 182.783 89.124  112.212 1.00 177.59 ? 414 ILE B N   1 
ATOM   4408  C CA  . ILE B 2 392 ? 183.918 89.259  111.303 1.00 177.59 ? 414 ILE B CA  1 
ATOM   4409  C C   . ILE B 2 392 ? 184.137 87.924  110.602 1.00 177.59 ? 414 ILE B C   1 
ATOM   4410  O O   . ILE B 2 392 ? 184.578 86.956  111.238 1.00 177.59 ? 414 ILE B O   1 
ATOM   4411  C CB  . ILE B 2 392 ? 185.184 89.711  112.048 1.00 177.59 ? 414 ILE B CB  1 
ATOM   4412  C CG1 . ILE B 2 392 ? 184.971 91.091  112.675 1.00 177.59 ? 414 ILE B CG1 1 
ATOM   4413  C CG2 . ILE B 2 392 ? 186.379 89.728  111.105 1.00 177.59 ? 414 ILE B CG2 1 
ATOM   4414  C CD1 . ILE B 2 392 ? 186.206 91.656  113.344 1.00 177.59 ? 414 ILE B CD1 1 
ATOM   4415  N N   . PRO B 2 393 ? 183.842 87.820  109.310 1.00 194.08 ? 415 PRO B N   1 
ATOM   4416  C CA  . PRO B 2 393 ? 184.029 86.547  108.607 1.00 194.08 ? 415 PRO B CA  1 
ATOM   4417  C C   . PRO B 2 393 ? 185.504 86.253  108.373 1.00 194.08 ? 415 PRO B C   1 
ATOM   4418  O O   . PRO B 2 393 ? 186.380 87.105  108.535 1.00 194.08 ? 415 PRO B O   1 
ATOM   4419  C CB  . PRO B 2 393 ? 183.283 86.757  107.288 1.00 194.08 ? 415 PRO B CB  1 
ATOM   4420  C CG  . PRO B 2 393 ? 183.340 88.230  107.065 1.00 194.08 ? 415 PRO B CG  1 
ATOM   4421  C CD  . PRO B 2 393 ? 183.289 88.865  108.430 1.00 194.08 ? 415 PRO B CD  1 
ATOM   4422  N N   . SER B 2 394 ? 185.768 85.009  107.985 1.00 220.34 ? 416 SER B N   1 
ATOM   4423  C CA  . SER B 2 394 ? 187.130 84.594  107.701 1.00 220.34 ? 416 SER B CA  1 
ATOM   4424  C C   . SER B 2 394 ? 187.604 85.210  106.385 1.00 220.34 ? 416 SER B C   1 
ATOM   4425  O O   . SER B 2 394 ? 186.797 85.491  105.495 1.00 220.34 ? 416 SER B O   1 
ATOM   4426  C CB  . SER B 2 394 ? 187.221 83.072  107.628 1.00 220.34 ? 416 SER B CB  1 
ATOM   4427  O OG  . SER B 2 394 ? 186.955 82.610  106.318 1.00 220.34 ? 416 SER B OG  1 
ATOM   4428  N N   . PRO B 2 395 ? 188.914 85.436  106.239 1.00 229.06 ? 417 PRO B N   1 
ATOM   4429  C CA  . PRO B 2 395 ? 189.421 86.068  105.009 1.00 229.06 ? 417 PRO B CA  1 
ATOM   4430  C C   . PRO B 2 395 ? 189.233 85.232  103.753 1.00 229.06 ? 417 PRO B C   1 
ATOM   4431  O O   . PRO B 2 395 ? 189.399 85.770  102.650 1.00 229.06 ? 417 PRO B O   1 
ATOM   4432  C CB  . PRO B 2 395 ? 190.913 86.280  105.309 1.00 229.06 ? 417 PRO B CB  1 
ATOM   4433  C CG  . PRO B 2 395 ? 191.028 86.204  106.800 1.00 229.06 ? 417 PRO B CG  1 
ATOM   4434  C CD  . PRO B 2 395 ? 189.980 85.232  107.234 1.00 229.06 ? 417 PRO B CD  1 
ATOM   4435  N N   . HIS B 2 396 ? 188.895 83.947  103.872 1.00 235.02 ? 418 HIS B N   1 
ATOM   4436  C CA  . HIS B 2 396 ? 188.735 83.071  102.717 1.00 235.02 ? 418 HIS B CA  1 
ATOM   4437  C C   . HIS B 2 396 ? 187.277 82.930  102.289 1.00 235.02 ? 418 HIS B C   1 
ATOM   4438  O O   . HIS B 2 396 ? 186.889 81.892  101.742 1.00 235.02 ? 418 HIS B O   1 
ATOM   4439  C CB  . HIS B 2 396 ? 189.351 81.699  103.001 1.00 235.02 ? 418 HIS B CB  1 
ATOM   4440  C CG  . HIS B 2 396 ? 188.684 80.946  104.111 1.00 235.02 ? 418 HIS B CG  1 
ATOM   4441  N ND1 . HIS B 2 396 ? 187.392 80.473  104.023 1.00 235.02 ? 418 HIS B ND1 1 
ATOM   4442  C CD2 . HIS B 2 396 ? 189.136 80.578  105.334 1.00 235.02 ? 418 HIS B CD2 1 
ATOM   4443  C CE1 . HIS B 2 396 ? 187.076 79.848  105.143 1.00 235.02 ? 418 HIS B CE1 1 
ATOM   4444  N NE2 . HIS B 2 396 ? 188.116 79.899  105.956 1.00 235.02 ? 418 HIS B NE2 1 
ATOM   4445  N N   . VAL B 2 397 ? 186.462 83.954  102.527 1.00 240.94 ? 419 VAL B N   1 
ATOM   4446  C CA  . VAL B 2 397 ? 185.067 83.979  102.100 1.00 240.94 ? 419 VAL B CA  1 
ATOM   4447  C C   . VAL B 2 397 ? 184.909 85.062  101.044 1.00 240.94 ? 419 VAL B C   1 
ATOM   4448  O O   . VAL B 2 397 ? 185.326 86.208  101.252 1.00 240.94 ? 419 VAL B O   1 
ATOM   4449  C CB  . VAL B 2 397 ? 184.113 84.222  103.282 1.00 240.94 ? 419 VAL B CB  1 
ATOM   4450  C CG1 . VAL B 2 397 ? 182.676 83.944  102.867 1.00 240.94 ? 419 VAL B CG1 1 
ATOM   4451  C CG2 . VAL B 2 397 ? 184.500 83.353  104.464 1.00 240.94 ? 419 VAL B CG2 1 
ATOM   4452  N N   . THR B 2 398 ? 184.308 84.700  99.915  1.00 245.14 ? 420 THR B N   1 
ATOM   4453  C CA  . THR B 2 398 ? 184.067 85.627  98.818  1.00 245.14 ? 420 THR B CA  1 
ATOM   4454  C C   . THR B 2 398 ? 182.613 86.078  98.846  1.00 245.14 ? 420 THR B C   1 
ATOM   4455  O O   . THR B 2 398 ? 181.708 85.258  99.035  1.00 245.14 ? 420 THR B O   1 
ATOM   4456  C CB  . THR B 2 398 ? 184.393 84.979  97.471  1.00 245.14 ? 420 THR B CB  1 
ATOM   4457  O OG1 . THR B 2 398 ? 185.648 84.293  97.561  1.00 245.14 ? 420 THR B OG1 1 
ATOM   4458  C CG2 . THR B 2 398 ? 184.475 86.034  96.378  1.00 245.14 ? 420 THR B CG2 1 
ATOM   4459  N N   . ALA B 2 399 ? 182.395 87.378  98.664  1.00 243.28 ? 421 ALA B N   1 
ATOM   4460  C CA  . ALA B 2 399 ? 181.042 87.919  98.661  1.00 243.28 ? 421 ALA B CA  1 
ATOM   4461  C C   . ALA B 2 399 ? 180.264 87.390  97.463  1.00 243.28 ? 421 ALA B C   1 
ATOM   4462  O O   . ALA B 2 399 ? 180.727 87.471  96.321  1.00 243.28 ? 421 ALA B O   1 
ATOM   4463  C CB  . ALA B 2 399 ? 181.081 89.446  98.638  1.00 243.28 ? 421 ALA B CB  1 
ATOM   4464  N N   . ALA B 2 400 ? 179.074 86.848  97.726  1.00 238.48 ? 422 ALA B N   1 
ATOM   4465  C CA  . ALA B 2 400 ? 178.239 86.281  96.677  1.00 238.48 ? 422 ALA B CA  1 
ATOM   4466  C C   . ALA B 2 400 ? 177.085 87.184  96.267  1.00 238.48 ? 422 ALA B C   1 
ATOM   4467  O O   . ALA B 2 400 ? 176.530 86.995  95.179  1.00 238.48 ? 422 ALA B O   1 
ATOM   4468  C CB  . ALA B 2 400 ? 177.678 84.924  97.121  1.00 238.48 ? 422 ALA B CB  1 
ATOM   4469  N N   . TYR B 2 401 ? 176.715 88.154  97.099  1.00 229.71 ? 423 TYR B N   1 
ATOM   4470  C CA  . TYR B 2 401 ? 175.617 89.066  96.812  1.00 229.71 ? 423 TYR B CA  1 
ATOM   4471  C C   . TYR B 2 401 ? 176.120 90.499  96.883  1.00 229.71 ? 423 TYR B C   1 
ATOM   4472  O O   . TYR B 2 401 ? 176.678 90.915  97.904  1.00 229.71 ? 423 TYR B O   1 
ATOM   4473  C CB  . TYR B 2 401 ? 174.457 88.861  97.792  1.00 229.71 ? 423 TYR B CB  1 
ATOM   4474  C CG  . TYR B 2 401 ? 173.731 87.547  97.617  1.00 229.71 ? 423 TYR B CG  1 
ATOM   4475  C CD1 . TYR B 2 401 ? 172.689 87.424  96.707  1.00 229.71 ? 423 TYR B CD1 1 
ATOM   4476  C CD2 . TYR B 2 401 ? 174.087 86.431  98.361  1.00 229.71 ? 423 TYR B CD2 1 
ATOM   4477  C CE1 . TYR B 2 401 ? 172.022 86.225  96.544  1.00 229.71 ? 423 TYR B CE1 1 
ATOM   4478  C CE2 . TYR B 2 401 ? 173.426 85.228  98.205  1.00 229.71 ? 423 TYR B CE2 1 
ATOM   4479  C CZ  . TYR B 2 401 ? 172.394 85.130  97.295  1.00 229.71 ? 423 TYR B CZ  1 
ATOM   4480  O OH  . TYR B 2 401 ? 171.733 83.935  97.135  1.00 229.71 ? 423 TYR B OH  1 
ATOM   4481  N N   . SER B 2 402 ? 175.922 91.247  95.802  1.00 228.16 ? 424 SER B N   1 
ATOM   4482  C CA  . SER B 2 402 ? 176.316 92.644  95.731  1.00 228.16 ? 424 SER B CA  1 
ATOM   4483  C C   . SER B 2 402 ? 175.120 93.484  95.307  1.00 228.16 ? 424 SER B C   1 
ATOM   4484  O O   . SER B 2 402 ? 174.117 92.968  94.809  1.00 228.16 ? 424 SER B O   1 
ATOM   4485  C CB  . SER B 2 402 ? 177.482 92.854  94.754  1.00 228.16 ? 424 SER B CB  1 
ATOM   4486  O OG  . SER B 2 402 ? 177.009 93.058  93.433  1.00 228.16 ? 424 SER B OG  1 
ATOM   4487  N N   . VAL B 2 403 ? 175.240 94.791  95.510  1.00 225.89 ? 425 VAL B N   1 
ATOM   4488  C CA  . VAL B 2 403 ? 174.170 95.715  95.156  1.00 225.89 ? 425 VAL B CA  1 
ATOM   4489  C C   . VAL B 2 403 ? 174.258 96.055  93.674  1.00 225.89 ? 425 VAL B C   1 
ATOM   4490  O O   . VAL B 2 403 ? 175.334 96.026  93.065  1.00 225.89 ? 425 VAL B O   1 
ATOM   4491  C CB  . VAL B 2 403 ? 174.231 96.981  96.034  1.00 225.89 ? 425 VAL B CB  1 
ATOM   4492  C CG1 . VAL B 2 403 ? 174.237 96.603  97.505  1.00 225.89 ? 425 VAL B CG1 1 
ATOM   4493  C CG2 . VAL B 2 403 ? 175.458 97.810  95.692  1.00 225.89 ? 425 VAL B CG2 1 
ATOM   4494  N N   . VAL B 2 404 ? 173.106 96.370  93.083  1.00 223.62 ? 426 VAL B N   1 
ATOM   4495  C CA  . VAL B 2 404 ? 173.008 96.730  91.676  1.00 223.62 ? 426 VAL B CA  1 
ATOM   4496  C C   . VAL B 2 404 ? 172.228 98.034  91.561  1.00 223.62 ? 426 VAL B C   1 
ATOM   4497  O O   . VAL B 2 404 ? 171.592 98.491  92.512  1.00 223.62 ? 426 VAL B O   1 
ATOM   4498  C CB  . VAL B 2 404 ? 172.344 95.624  90.829  1.00 223.62 ? 426 VAL B CB  1 
ATOM   4499  C CG1 . VAL B 2 404 ? 173.190 94.360  90.845  1.00 223.62 ? 426 VAL B CG1 1 
ATOM   4500  C CG2 . VAL B 2 404 ? 170.940 95.338  91.337  1.00 223.62 ? 426 VAL B CG2 1 
ATOM   4501  N N   . ASN B 2 405 ? 172.289 98.629  90.369  1.00 223.53 ? 427 ASN B N   1 
ATOM   4502  C CA  . ASN B 2 405 ? 171.604 99.885  90.061  1.00 223.53 ? 427 ASN B CA  1 
ATOM   4503  C C   . ASN B 2 405 ? 172.036 100.994 91.023  1.00 223.53 ? 427 ASN B C   1 
ATOM   4504  O O   . ASN B 2 405 ? 171.240 101.547 91.786  1.00 223.53 ? 427 ASN B O   1 
ATOM   4505  C CB  . ASN B 2 405 ? 170.082 99.697  90.072  1.00 223.53 ? 427 ASN B CB  1 
ATOM   4506  C CG  . ASN B 2 405 ? 169.342 100.892 89.505  1.00 223.53 ? 427 ASN B CG  1 
ATOM   4507  O OD1 . ASN B 2 405 ? 169.904 101.685 88.749  1.00 223.53 ? 427 ASN B OD1 1 
ATOM   4508  N ND2 . ASN B 2 405 ? 168.072 101.029 89.869  1.00 223.53 ? 427 ASN B ND2 1 
ATOM   4509  N N   . LEU B 2 406 ? 173.327 101.308 90.976  1.00 224.73 ? 428 LEU B N   1 
ATOM   4510  C CA  . LEU B 2 406 ? 173.913 102.357 91.799  1.00 224.73 ? 428 LEU B CA  1 
ATOM   4511  C C   . LEU B 2 406 ? 173.957 103.658 91.010  1.00 224.73 ? 428 LEU B C   1 
ATOM   4512  O O   . LEU B 2 406 ? 174.486 103.696 89.894  1.00 224.73 ? 428 LEU B O   1 
ATOM   4513  C CB  . LEU B 2 406 ? 175.318 101.968 92.261  1.00 224.73 ? 428 LEU B CB  1 
ATOM   4514  C CG  . LEU B 2 406 ? 175.404 100.887 93.340  1.00 224.73 ? 428 LEU B CG  1 
ATOM   4515  C CD1 . LEU B 2 406 ? 176.853 100.546 93.646  1.00 224.73 ? 428 LEU B CD1 1 
ATOM   4516  C CD2 . LEU B 2 406 ? 174.682 101.334 94.600  1.00 224.73 ? 428 LEU B CD2 1 
ATOM   4517  N N   . LYS B 2 407 ? 173.400 104.718 91.591  1.00 221.30 ? 429 LYS B N   1 
ATOM   4518  C CA  . LYS B 2 407 ? 173.355 106.017 90.936  1.00 221.30 ? 429 LYS B CA  1 
ATOM   4519  C C   . LYS B 2 407 ? 173.296 107.106 91.996  1.00 221.30 ? 429 LYS B C   1 
ATOM   4520  O O   . LYS B 2 407 ? 172.649 106.938 93.033  1.00 221.30 ? 429 LYS B O   1 
ATOM   4521  C CB  . LYS B 2 407 ? 172.150 106.126 89.994  1.00 221.30 ? 429 LYS B CB  1 
ATOM   4522  C CG  . LYS B 2 407 ? 172.113 107.403 89.170  1.00 221.30 ? 429 LYS B CG  1 
ATOM   4523  C CD  . LYS B 2 407 ? 170.854 107.479 88.323  1.00 221.30 ? 429 LYS B CD  1 
ATOM   4524  C CE  . LYS B 2 407 ? 170.829 108.746 87.485  1.00 221.30 ? 429 LYS B CE  1 
ATOM   4525  N NZ  . LYS B 2 407 ? 170.895 109.971 88.330  1.00 221.30 ? 429 LYS B NZ  1 
ATOM   4526  N N   . ALA B 2 408 ? 173.977 108.218 91.728  1.00 219.47 ? 430 ALA B N   1 
ATOM   4527  C CA  . ALA B 2 408 ? 174.000 109.363 92.625  1.00 219.47 ? 430 ALA B CA  1 
ATOM   4528  C C   . ALA B 2 408 ? 173.794 110.638 91.822  1.00 219.47 ? 430 ALA B C   1 
ATOM   4529  O O   . ALA B 2 408 ? 174.307 110.769 90.706  1.00 219.47 ? 430 ALA B O   1 
ATOM   4530  C CB  . ALA B 2 408 ? 175.319 109.439 93.402  1.00 219.47 ? 430 ALA B CB  1 
ATOM   4531  N N   . PHE B 2 409 ? 173.038 111.577 92.394  1.00 215.04 ? 431 PHE B N   1 
ATOM   4532  C CA  . PHE B 2 409 ? 172.751 112.835 91.729  1.00 215.04 ? 431 PHE B CA  1 
ATOM   4533  C C   . PHE B 2 409 ? 172.609 113.928 92.780  1.00 215.04 ? 431 PHE B C   1 
ATOM   4534  O O   . PHE B 2 409 ? 171.946 113.703 93.805  1.00 215.04 ? 431 PHE B O   1 
ATOM   4535  C CB  . PHE B 2 409 ? 171.480 112.759 90.878  1.00 215.04 ? 431 PHE B CB  1 
ATOM   4536  C CG  . PHE B 2 409 ? 170.328 112.069 91.558  1.00 215.04 ? 431 PHE B CG  1 
ATOM   4537  C CD1 . PHE B 2 409 ? 170.165 110.696 91.456  1.00 215.04 ? 431 PHE B CD1 1 
ATOM   4538  C CD2 . PHE B 2 409 ? 169.402 112.795 92.289  1.00 215.04 ? 431 PHE B CD2 1 
ATOM   4539  C CE1 . PHE B 2 409 ? 169.106 110.061 92.078  1.00 215.04 ? 431 PHE B CE1 1 
ATOM   4540  C CE2 . PHE B 2 409 ? 168.341 112.165 92.913  1.00 215.04 ? 431 PHE B CE2 1 
ATOM   4541  C CZ  . PHE B 2 409 ? 168.192 110.797 92.806  1.00 215.04 ? 431 PHE B CZ  1 
ATOM   4542  N N   . PRO B 2 410 ? 173.216 115.098 92.569  1.00 214.76 ? 432 PRO B N   1 
ATOM   4543  C CA  . PRO B 2 410 ? 173.091 116.185 93.549  1.00 214.76 ? 432 PRO B CA  1 
ATOM   4544  C C   . PRO B 2 410 ? 171.771 116.924 93.378  1.00 214.76 ? 432 PRO B C   1 
ATOM   4545  O O   . PRO B 2 410 ? 171.399 117.312 92.268  1.00 214.76 ? 432 PRO B O   1 
ATOM   4546  C CB  . PRO B 2 410 ? 174.286 117.090 93.228  1.00 214.76 ? 432 PRO B CB  1 
ATOM   4547  C CG  . PRO B 2 410 ? 174.530 116.869 91.771  1.00 214.76 ? 432 PRO B CG  1 
ATOM   4548  C CD  . PRO B 2 410 ? 174.132 115.443 91.467  1.00 214.76 ? 432 PRO B CD  1 
ATOM   4549  N N   . LYS B 2 411 ? 171.061 117.116 94.489  1.00 210.75 ? 433 LYS B N   1 
ATOM   4550  C CA  . LYS B 2 411 ? 169.786 117.820 94.490  1.00 210.75 ? 433 LYS B CA  1 
ATOM   4551  C C   . LYS B 2 411 ? 169.704 118.695 95.729  1.00 210.75 ? 433 LYS B C   1 
ATOM   4552  O O   . LYS B 2 411 ? 169.887 118.205 96.848  1.00 210.75 ? 433 LYS B O   1 
ATOM   4553  C CB  . LYS B 2 411 ? 168.607 116.840 94.455  1.00 210.75 ? 433 LYS B CB  1 
ATOM   4554  C CG  . LYS B 2 411 ? 168.429 116.128 93.126  1.00 210.75 ? 433 LYS B CG  1 
ATOM   4555  C CD  . LYS B 2 411 ? 168.157 117.116 92.004  1.00 210.75 ? 433 LYS B CD  1 
ATOM   4556  C CE  . LYS B 2 411 ? 168.146 116.422 90.652  1.00 210.75 ? 433 LYS B CE  1 
ATOM   4557  N NZ  . LYS B 2 411 ? 169.437 115.731 90.377  1.00 210.75 ? 433 LYS B NZ  1 
ATOM   4558  N N   . ASP B 2 412 ? 169.426 119.984 95.523  1.00 209.90 ? 434 ASP B N   1 
ATOM   4559  C CA  . ASP B 2 412 ? 169.328 120.962 96.609  1.00 209.90 ? 434 ASP B CA  1 
ATOM   4560  C C   . ASP B 2 412 ? 170.610 120.972 97.443  1.00 209.90 ? 434 ASP B C   1 
ATOM   4561  O O   . ASP B 2 412 ? 170.581 120.931 98.675  1.00 209.90 ? 434 ASP B O   1 
ATOM   4562  C CB  . ASP B 2 412 ? 168.098 120.691 97.481  1.00 209.90 ? 434 ASP B CB  1 
ATOM   4563  C CG  . ASP B 2 412 ? 167.691 121.893 98.320  1.00 209.90 ? 434 ASP B CG  1 
ATOM   4564  O OD1 . ASP B 2 412 ? 168.531 122.790 98.547  1.00 209.90 ? 434 ASP B OD1 1 
ATOM   4565  O OD2 . ASP B 2 412 ? 166.522 121.938 98.756  1.00 209.90 ? 434 ASP B OD2 1 
ATOM   4566  N N   . ASN B 2 413 ? 171.748 121.010 96.748  1.00 210.98 ? 435 ASN B N   1 
ATOM   4567  C CA  . ASN B 2 413 ? 173.079 121.020 97.354  1.00 210.98 ? 435 ASN B CA  1 
ATOM   4568  C C   . ASN B 2 413 ? 173.351 119.774 98.194  1.00 210.98 ? 435 ASN B C   1 
ATOM   4569  O O   . ASN B 2 413 ? 174.260 119.773 99.031  1.00 210.98 ? 435 ASN B O   1 
ATOM   4570  C CB  . ASN B 2 413 ? 173.298 122.283 98.197  1.00 210.98 ? 435 ASN B CB  1 
ATOM   4571  C CG  . ASN B 2 413 ? 172.898 123.547 97.465  1.00 210.98 ? 435 ASN B CG  1 
ATOM   4572  O OD1 . ASN B 2 413 ? 172.874 123.585 96.234  1.00 210.98 ? 435 ASN B OD1 1 
ATOM   4573  N ND2 . ASN B 2 413 ? 172.580 124.593 98.219  1.00 210.98 ? 435 ASN B ND2 1 
ATOM   4574  N N   . LEU B 2 414 ? 172.582 118.707 97.988  1.00 209.54 ? 436 LEU B N   1 
ATOM   4575  C CA  . LEU B 2 414 ? 172.777 117.439 98.679  1.00 209.54 ? 436 LEU B CA  1 
ATOM   4576  C C   . LEU B 2 414 ? 172.972 116.338 97.649  1.00 209.54 ? 436 LEU B C   1 
ATOM   4577  O O   . LEU B 2 414 ? 172.130 116.154 96.764  1.00 209.54 ? 436 LEU B O   1 
ATOM   4578  C CB  . LEU B 2 414 ? 171.589 117.106 99.587  1.00 209.54 ? 436 LEU B CB  1 
ATOM   4579  C CG  . LEU B 2 414 ? 170.960 118.239 100.401 1.00 209.54 ? 436 LEU B CG  1 
ATOM   4580  C CD1 . LEU B 2 414 ? 169.821 117.708 101.256 1.00 209.54 ? 436 LEU B CD1 1 
ATOM   4581  C CD2 . LEU B 2 414 ? 172.003 118.923 101.271 1.00 209.54 ? 436 LEU B CD2 1 
ATOM   4582  N N   . LEU B 2 415 ? 174.079 115.609 97.766  1.00 210.48 ? 437 LEU B N   1 
ATOM   4583  C CA  . LEU B 2 415 ? 174.393 114.525 96.838  1.00 210.48 ? 437 LEU B CA  1 
ATOM   4584  C C   . LEU B 2 415 ? 173.634 113.279 97.276  1.00 210.48 ? 437 LEU B C   1 
ATOM   4585  O O   . LEU B 2 415 ? 174.103 112.515 98.123  1.00 210.48 ? 437 LEU B O   1 
ATOM   4586  C CB  . LEU B 2 415 ? 175.896 114.276 96.793  1.00 210.48 ? 437 LEU B CB  1 
ATOM   4587  C CG  . LEU B 2 415 ? 176.388 113.295 95.728  1.00 210.48 ? 437 LEU B CG  1 
ATOM   4588  C CD1 . LEU B 2 415 ? 175.985 113.767 94.340  1.00 210.48 ? 437 LEU B CD1 1 
ATOM   4589  C CD2 . LEU B 2 415 ? 177.895 113.116 95.821  1.00 210.48 ? 437 LEU B CD2 1 
ATOM   4590  N N   . TRP B 2 416 ? 172.455 113.070 96.698  1.00 209.11 ? 438 TRP B N   1 
ATOM   4591  C CA  . TRP B 2 416 ? 171.624 111.923 97.030  1.00 209.11 ? 438 TRP B CA  1 
ATOM   4592  C C   . TRP B 2 416 ? 172.085 110.695 96.257  1.00 209.11 ? 438 TRP B C   1 
ATOM   4593  O O   . TRP B 2 416 ? 172.379 110.772 95.061  1.00 209.11 ? 438 TRP B O   1 
ATOM   4594  C CB  . TRP B 2 416 ? 170.154 112.213 96.719  1.00 209.11 ? 438 TRP B CB  1 
ATOM   4595  C CG  . TRP B 2 416 ? 169.531 113.222 97.633  1.00 209.11 ? 438 TRP B CG  1 
ATOM   4596  C CD1 . TRP B 2 416 ? 169.590 114.580 97.517  1.00 209.11 ? 438 TRP B CD1 1 
ATOM   4597  C CD2 . TRP B 2 416 ? 168.751 112.953 98.804  1.00 209.11 ? 438 TRP B CD2 1 
ATOM   4598  N NE1 . TRP B 2 416 ? 168.896 115.173 98.544  1.00 209.11 ? 438 TRP B NE1 1 
ATOM   4599  C CE2 . TRP B 2 416 ? 168.372 114.196 99.348  1.00 209.11 ? 438 TRP B CE2 1 
ATOM   4600  C CE3 . TRP B 2 416 ? 168.338 111.781 99.446  1.00 209.11 ? 438 TRP B CE3 1 
ATOM   4601  C CZ2 . TRP B 2 416 ? 167.599 114.301 100.503 1.00 209.11 ? 438 TRP B CZ2 1 
ATOM   4602  C CZ3 . TRP B 2 416 ? 167.571 111.888 100.593 1.00 209.11 ? 438 TRP B CZ3 1 
ATOM   4603  C CH2 . TRP B 2 416 ? 167.210 113.139 101.109 1.00 209.11 ? 438 TRP B CH2 1 
ATOM   4604  N N   . VAL B 2 417 ? 172.149 109.562 96.952  1.00 213.31 ? 439 VAL B N   1 
ATOM   4605  C CA  . VAL B 2 417 ? 172.552 108.289 96.366  1.00 213.31 ? 439 VAL B CA  1 
ATOM   4606  C C   . VAL B 2 417 ? 171.427 107.287 96.581  1.00 213.31 ? 439 VAL B C   1 
ATOM   4607  O O   . VAL B 2 417 ? 170.919 107.149 97.699  1.00 213.31 ? 439 VAL B O   1 
ATOM   4608  C CB  . VAL B 2 417 ? 173.868 107.769 96.974  1.00 213.31 ? 439 VAL B CB  1 
ATOM   4609  C CG1 . VAL B 2 417 ? 174.435 106.641 96.125  1.00 213.31 ? 439 VAL B CG1 1 
ATOM   4610  C CG2 . VAL B 2 417 ? 174.878 108.899 97.112  1.00 213.31 ? 439 VAL B CG2 1 
ATOM   4611  N N   . GLU B 2 418 ? 171.043 106.593 95.514  1.00 215.12 ? 440 GLU B N   1 
ATOM   4612  C CA  . GLU B 2 418 ? 169.990 105.592 95.561  1.00 215.12 ? 440 GLU B CA  1 
ATOM   4613  C C   . GLU B 2 418 ? 170.550 104.232 95.163  1.00 215.12 ? 440 GLU B C   1 
ATOM   4614  O O   . GLU B 2 418 ? 171.555 104.132 94.455  1.00 215.12 ? 440 GLU B O   1 
ATOM   4615  C CB  . GLU B 2 418 ? 168.822 105.968 94.641  1.00 215.12 ? 440 GLU B CB  1 
ATOM   4616  C CG  . GLU B 2 418 ? 169.208 106.113 93.179  1.00 215.12 ? 440 GLU B CG  1 
ATOM   4617  C CD  . GLU B 2 418 ? 168.030 106.484 92.300  1.00 215.12 ? 440 GLU B CD  1 
ATOM   4618  O OE1 . GLU B 2 418 ? 166.912 106.634 92.835  1.00 215.12 ? 440 GLU B OE1 1 
ATOM   4619  O OE2 . GLU B 2 418 ? 168.222 106.626 91.074  1.00 215.12 ? 440 GLU B OE2 1 
ATOM   4620  N N   . TRP B 2 419 ? 169.882 103.180 95.629  1.00 209.76 ? 441 TRP B N   1 
ATOM   4621  C CA  . TRP B 2 419 ? 170.304 101.818 95.335  1.00 209.76 ? 441 TRP B CA  1 
ATOM   4622  C C   . TRP B 2 419 ? 169.104 100.892 95.469  1.00 209.76 ? 441 TRP B C   1 
ATOM   4623  O O   . TRP B 2 419 ? 168.056 101.269 96.000  1.00 209.76 ? 441 TRP B O   1 
ATOM   4624  C CB  . TRP B 2 419 ? 171.445 101.373 96.257  1.00 209.76 ? 441 TRP B CB  1 
ATOM   4625  C CG  . TRP B 2 419 ? 171.073 101.334 97.709  1.00 209.76 ? 441 TRP B CG  1 
ATOM   4626  C CD1 . TRP B 2 419 ? 170.511 100.290 98.385  1.00 209.76 ? 441 TRP B CD1 1 
ATOM   4627  C CD2 . TRP B 2 419 ? 171.243 102.386 98.667  1.00 209.76 ? 441 TRP B CD2 1 
ATOM   4628  N NE1 . TRP B 2 419 ? 170.318 100.627 99.703  1.00 209.76 ? 441 TRP B NE1 1 
ATOM   4629  C CE2 . TRP B 2 419 ? 170.760 101.908 99.902  1.00 209.76 ? 441 TRP B CE2 1 
ATOM   4630  C CE3 . TRP B 2 419 ? 171.756 103.685 98.600  1.00 209.76 ? 441 TRP B CE3 1 
ATOM   4631  C CZ2 . TRP B 2 419 ? 170.774 102.684 101.059 1.00 209.76 ? 441 TRP B CZ2 1 
ATOM   4632  C CZ3 . TRP B 2 419 ? 171.770 104.453 99.751  1.00 209.76 ? 441 TRP B CZ3 1 
ATOM   4633  C CH2 . TRP B 2 419 ? 171.282 103.950 100.963 1.00 209.76 ? 441 TRP B CH2 1 
ATOM   4634  N N   . THR B 2 420 ? 169.274 99.667  94.975  1.00 214.52 ? 442 THR B N   1 
ATOM   4635  C CA  . THR B 2 420 ? 168.248 98.641  95.053  1.00 214.52 ? 442 THR B CA  1 
ATOM   4636  C C   . THR B 2 420 ? 168.665 97.568  96.044  1.00 214.52 ? 442 THR B C   1 
ATOM   4637  O O   . THR B 2 420 ? 169.815 97.111  96.004  1.00 214.52 ? 442 THR B O   1 
ATOM   4638  C CB  . THR B 2 420 ? 168.003 98.010  93.678  1.00 214.52 ? 442 THR B CB  1 
ATOM   4639  O OG1 . THR B 2 420 ? 169.219 97.425  93.196  1.00 214.52 ? 442 THR B OG1 1 
ATOM   4640  C CG2 . THR B 2 420 ? 167.524 99.061  92.689  1.00 214.52 ? 442 THR B CG2 1 
ATOM   4641  N N   . PRO B 2 421 ? 167.777 97.148  96.939  1.00 220.03 ? 443 PRO B N   1 
ATOM   4642  C CA  . PRO B 2 421 ? 168.138 96.128  97.928  1.00 220.03 ? 443 PRO B CA  1 
ATOM   4643  C C   . PRO B 2 421 ? 168.402 94.790  97.262  1.00 220.03 ? 443 PRO B C   1 
ATOM   4644  O O   . PRO B 2 421 ? 167.745 94.437  96.272  1.00 220.03 ? 443 PRO B O   1 
ATOM   4645  C CB  . PRO B 2 421 ? 166.902 96.061  98.840  1.00 220.03 ? 443 PRO B CB  1 
ATOM   4646  C CG  . PRO B 2 421 ? 166.159 97.338  98.586  1.00 220.03 ? 443 PRO B CG  1 
ATOM   4647  C CD  . PRO B 2 421 ? 166.416 97.668  97.152  1.00 220.03 ? 443 PRO B CD  1 
ATOM   4648  N N   . PRO B 2 422 ? 169.360 94.021  97.771  1.00 218.89 ? 444 PRO B N   1 
ATOM   4649  C CA  . PRO B 2 422 ? 169.620 92.686  97.220  1.00 218.89 ? 444 PRO B CA  1 
ATOM   4650  C C   . PRO B 2 422 ? 168.459 91.751  97.500  1.00 218.89 ? 444 PRO B C   1 
ATOM   4651  O O   . PRO B 2 422 ? 167.642 92.013  98.397  1.00 218.89 ? 444 PRO B O   1 
ATOM   4652  C CB  . PRO B 2 422 ? 170.891 92.237  97.961  1.00 218.89 ? 444 PRO B CB  1 
ATOM   4653  C CG  . PRO B 2 422 ? 171.483 93.492  98.527  1.00 218.89 ? 444 PRO B CG  1 
ATOM   4654  C CD  . PRO B 2 422 ? 170.320 94.380  98.827  1.00 218.89 ? 444 PRO B CD  1 
ATOM   4655  N N   . PRO B 2 423 ? 168.346 90.645  96.757  1.00 220.24 ? 445 PRO B N   1 
ATOM   4656  C CA  . PRO B 2 423 ? 167.244 89.700  96.999  1.00 220.24 ? 445 PRO B CA  1 
ATOM   4657  C C   . PRO B 2 423 ? 167.363 88.923  98.300  1.00 220.24 ? 445 PRO B C   1 
ATOM   4658  O O   . PRO B 2 423 ? 166.470 88.124  98.605  1.00 220.24 ? 445 PRO B O   1 
ATOM   4659  C CB  . PRO B 2 423 ? 167.322 88.758  95.788  1.00 220.24 ? 445 PRO B CB  1 
ATOM   4660  C CG  . PRO B 2 423 ? 168.744 88.831  95.349  1.00 220.24 ? 445 PRO B CG  1 
ATOM   4661  C CD  . PRO B 2 423 ? 169.178 90.244  95.609  1.00 220.24 ? 445 PRO B CD  1 
ATOM   4662  N N   . LYS B 2 424 ? 168.431 89.127  99.079  1.00 216.24 ? 446 LYS B N   1 
ATOM   4663  C CA  . LYS B 2 424 ? 168.635 88.461  100.354 1.00 216.24 ? 446 LYS B CA  1 
ATOM   4664  C C   . LYS B 2 424 ? 168.353 89.417  101.508 1.00 216.24 ? 446 LYS B C   1 
ATOM   4665  O O   . LYS B 2 424 ? 168.518 90.633  101.370 1.00 216.24 ? 446 LYS B O   1 
ATOM   4666  C CB  . LYS B 2 424 ? 170.069 87.935  100.465 1.00 216.24 ? 446 LYS B CB  1 
ATOM   4667  C CG  . LYS B 2 424 ? 170.292 86.596  99.782  1.00 216.24 ? 446 LYS B CG  1 
ATOM   4668  C CD  . LYS B 2 424 ? 169.463 85.500  100.432 1.00 216.24 ? 446 LYS B CD  1 
ATOM   4669  C CE  . LYS B 2 424 ? 169.714 84.155  99.772  1.00 216.24 ? 446 LYS B CE  1 
ATOM   4670  N NZ  . LYS B 2 424 ? 168.923 83.068  100.413 1.00 216.24 ? 446 LYS B NZ  1 
ATOM   4671  N N   . PRO B 2 425 ? 167.917 88.901  102.659 1.00 206.54 ? 447 PRO B N   1 
ATOM   4672  C CA  . PRO B 2 425 ? 167.616 89.778  103.802 1.00 206.54 ? 447 PRO B CA  1 
ATOM   4673  C C   . PRO B 2 425 ? 168.883 90.423  104.345 1.00 206.54 ? 447 PRO B C   1 
ATOM   4674  O O   . PRO B 2 425 ? 169.793 89.737  104.815 1.00 206.54 ? 447 PRO B O   1 
ATOM   4675  C CB  . PRO B 2 425 ? 166.980 88.826  104.823 1.00 206.54 ? 447 PRO B CB  1 
ATOM   4676  C CG  . PRO B 2 425 ? 167.488 87.474  104.446 1.00 206.54 ? 447 PRO B CG  1 
ATOM   4677  C CD  . PRO B 2 425 ? 167.620 87.488  102.953 1.00 206.54 ? 447 PRO B CD  1 
ATOM   4678  N N   . VAL B 2 426 ? 168.936 91.749  104.276 1.00 193.03 ? 448 VAL B N   1 
ATOM   4679  C CA  . VAL B 2 426 ? 170.066 92.510  104.779 1.00 193.03 ? 448 VAL B CA  1 
ATOM   4680  C C   . VAL B 2 426 ? 169.716 93.062  106.153 1.00 193.03 ? 448 VAL B C   1 
ATOM   4681  O O   . VAL B 2 426 ? 168.548 93.262  106.498 1.00 193.03 ? 448 VAL B O   1 
ATOM   4682  C CB  . VAL B 2 426 ? 170.471 93.647  103.813 1.00 193.03 ? 448 VAL B CB  1 
ATOM   4683  C CG1 . VAL B 2 426 ? 171.088 93.074  102.547 1.00 193.03 ? 448 VAL B CG1 1 
ATOM   4684  C CG2 . VAL B 2 426 ? 169.267 94.515  103.482 1.00 193.03 ? 448 VAL B CG2 1 
ATOM   4685  N N   . SER B 2 427 ? 170.749 93.316  106.955 1.00 180.62 ? 449 SER B N   1 
ATOM   4686  C CA  . SER B 2 427 ? 170.559 93.858  108.295 1.00 180.62 ? 449 SER B CA  1 
ATOM   4687  C C   . SER B 2 427 ? 170.649 95.380  108.312 1.00 180.62 ? 449 SER B C   1 
ATOM   4688  O O   . SER B 2 427 ? 169.795 96.049  108.901 1.00 180.62 ? 449 SER B O   1 
ATOM   4689  C CB  . SER B 2 427 ? 171.587 93.254  109.257 1.00 180.62 ? 449 SER B CB  1 
ATOM   4690  O OG  . SER B 2 427 ? 171.179 93.411  110.605 1.00 180.62 ? 449 SER B OG  1 
ATOM   4691  N N   . LYS B 2 428 ? 171.673 95.939  107.670 1.00 172.67 ? 450 LYS B N   1 
ATOM   4692  C CA  . LYS B 2 428 ? 171.851 97.383  107.617 1.00 172.67 ? 450 LYS B CA  1 
ATOM   4693  C C   . LYS B 2 428 ? 172.777 97.720  106.458 1.00 172.67 ? 450 LYS B C   1 
ATOM   4694  O O   . LYS B 2 428 ? 173.504 96.862  105.951 1.00 172.67 ? 450 LYS B O   1 
ATOM   4695  C CB  . LYS B 2 428 ? 172.408 97.933  108.934 1.00 172.67 ? 450 LYS B CB  1 
ATOM   4696  C CG  . LYS B 2 428 ? 173.730 97.316  109.358 1.00 172.67 ? 450 LYS B CG  1 
ATOM   4697  C CD  . LYS B 2 428 ? 174.183 97.865  110.701 1.00 172.67 ? 450 LYS B CD  1 
ATOM   4698  C CE  . LYS B 2 428 ? 175.500 97.245  111.136 1.00 172.67 ? 450 LYS B CE  1 
ATOM   4699  N NZ  . LYS B 2 428 ? 175.936 97.747  112.469 1.00 172.67 ? 450 LYS B NZ  1 
ATOM   4700  N N   . TYR B 2 429 ? 172.738 98.984  106.046 1.00 181.88 ? 451 TYR B N   1 
ATOM   4701  C CA  . TYR B 2 429 ? 173.539 99.477  104.936 1.00 181.88 ? 451 TYR B CA  1 
ATOM   4702  C C   . TYR B 2 429 ? 174.621 100.417 105.450 1.00 181.88 ? 451 TYR B C   1 
ATOM   4703  O O   . TYR B 2 429 ? 174.380 101.224 106.353 1.00 181.88 ? 451 TYR B O   1 
ATOM   4704  C CB  . TYR B 2 429 ? 172.667 100.200 103.907 1.00 181.88 ? 451 TYR B CB  1 
ATOM   4705  C CG  . TYR B 2 429 ? 171.772 99.278  103.113 1.00 181.88 ? 451 TYR B CG  1 
ATOM   4706  C CD1 . TYR B 2 429 ? 172.274 98.534  102.054 1.00 181.88 ? 451 TYR B CD1 1 
ATOM   4707  C CD2 . TYR B 2 429 ? 170.424 99.154  103.421 1.00 181.88 ? 451 TYR B CD2 1 
ATOM   4708  C CE1 . TYR B 2 429 ? 171.460 97.690  101.326 1.00 181.88 ? 451 TYR B CE1 1 
ATOM   4709  C CE2 . TYR B 2 429 ? 169.602 98.313  102.698 1.00 181.88 ? 451 TYR B CE2 1 
ATOM   4710  C CZ  . TYR B 2 429 ? 170.125 97.583  101.652 1.00 181.88 ? 451 TYR B CZ  1 
ATOM   4711  O OH  . TYR B 2 429 ? 169.309 96.744  100.930 1.00 181.88 ? 451 TYR B OH  1 
ATOM   4712  N N   . ILE B 2 430 ? 175.811 100.311 104.865 1.00 177.57 ? 452 ILE B N   1 
ATOM   4713  C CA  . ILE B 2 430 ? 176.962 101.122 105.242 1.00 177.57 ? 452 ILE B CA  1 
ATOM   4714  C C   . ILE B 2 430 ? 177.428 101.891 104.015 1.00 177.57 ? 452 ILE B C   1 
ATOM   4715  O O   . ILE B 2 430 ? 177.632 101.301 102.947 1.00 177.57 ? 452 ILE B O   1 
ATOM   4716  C CB  . ILE B 2 430 ? 178.103 100.259 105.812 1.00 177.57 ? 452 ILE B CB  1 
ATOM   4717  C CG1 . ILE B 2 430 ? 177.645 99.535  107.079 1.00 177.57 ? 452 ILE B CG1 1 
ATOM   4718  C CG2 . ILE B 2 430 ? 179.328 101.114 106.098 1.00 177.57 ? 452 ILE B CG2 1 
ATOM   4719  C CD1 . ILE B 2 430 ? 177.120 100.457 108.156 1.00 177.57 ? 452 ILE B CD1 1 
ATOM   4720  N N   . LEU B 2 431 ? 177.594 103.202 104.167 1.00 181.97 ? 453 LEU B N   1 
ATOM   4721  C CA  . LEU B 2 431 ? 178.068 104.068 103.098 1.00 181.97 ? 453 LEU B CA  1 
ATOM   4722  C C   . LEU B 2 431 ? 179.422 104.653 103.474 1.00 181.97 ? 453 LEU B C   1 
ATOM   4723  O O   . LEU B 2 431 ? 179.631 105.078 104.614 1.00 181.97 ? 453 LEU B O   1 
ATOM   4724  C CB  . LEU B 2 431 ? 177.072 105.197 102.810 1.00 181.97 ? 453 LEU B CB  1 
ATOM   4725  C CG  . LEU B 2 431 ? 175.588 104.828 102.856 1.00 181.97 ? 453 LEU B CG  1 
ATOM   4726  C CD1 . LEU B 2 431 ? 174.724 106.070 102.714 1.00 181.97 ? 453 LEU B CD1 1 
ATOM   4727  C CD2 . LEU B 2 431 ? 175.251 103.811 101.777 1.00 181.97 ? 453 LEU B CD2 1 
ATOM   4728  N N   . GLU B 2 432 ? 180.337 104.673 102.507 1.00 196.74 ? 454 GLU B N   1 
ATOM   4729  C CA  . GLU B 2 432 ? 181.680 105.194 102.711 1.00 196.74 ? 454 GLU B CA  1 
ATOM   4730  C C   . GLU B 2 432 ? 182.067 106.051 101.516 1.00 196.74 ? 454 GLU B C   1 
ATOM   4731  O O   . GLU B 2 432 ? 181.791 105.688 100.369 1.00 196.74 ? 454 GLU B O   1 
ATOM   4732  C CB  . GLU B 2 432 ? 182.695 104.058 102.903 1.00 196.74 ? 454 GLU B CB  1 
ATOM   4733  C CG  . GLU B 2 432 ? 184.089 104.517 103.299 1.00 196.74 ? 454 GLU B CG  1 
ATOM   4734  C CD  . GLU B 2 432 ? 185.013 104.669 102.106 1.00 196.74 ? 454 GLU B CD  1 
ATOM   4735  O OE1 . GLU B 2 432 ? 184.655 104.190 101.010 1.00 196.74 ? 454 GLU B OE1 1 
ATOM   4736  O OE2 . GLU B 2 432 ? 186.098 105.267 102.266 1.00 196.74 ? 454 GLU B OE2 1 
ATOM   4737  N N   . TRP B 2 433 ? 182.705 107.187 101.789 1.00 194.58 ? 455 TRP B N   1 
ATOM   4738  C CA  . TRP B 2 433 ? 183.087 108.116 100.738 1.00 194.58 ? 455 TRP B CA  1 
ATOM   4739  C C   . TRP B 2 433 ? 184.274 108.946 101.201 1.00 194.58 ? 455 TRP B C   1 
ATOM   4740  O O   . TRP B 2 433 ? 184.448 109.197 102.396 1.00 194.58 ? 455 TRP B O   1 
ATOM   4741  C CB  . TRP B 2 433 ? 181.923 109.036 100.351 1.00 194.58 ? 455 TRP B CB  1 
ATOM   4742  C CG  . TRP B 2 433 ? 181.692 110.147 101.330 1.00 194.58 ? 455 TRP B CG  1 
ATOM   4743  C CD1 . TRP B 2 433 ? 182.146 111.431 101.236 1.00 194.58 ? 455 TRP B CD1 1 
ATOM   4744  C CD2 . TRP B 2 433 ? 180.953 110.072 102.555 1.00 194.58 ? 455 TRP B CD2 1 
ATOM   4745  N NE1 . TRP B 2 433 ? 181.735 112.160 102.325 1.00 194.58 ? 455 TRP B NE1 1 
ATOM   4746  C CE2 . TRP B 2 433 ? 181.000 111.349 103.149 1.00 194.58 ? 455 TRP B CE2 1 
ATOM   4747  C CE3 . TRP B 2 433 ? 180.255 109.051 103.205 1.00 194.58 ? 455 TRP B CE3 1 
ATOM   4748  C CZ2 . TRP B 2 433 ? 180.376 111.630 104.362 1.00 194.58 ? 455 TRP B CZ2 1 
ATOM   4749  C CZ3 . TRP B 2 433 ? 179.637 109.332 104.409 1.00 194.58 ? 455 TRP B CZ3 1 
ATOM   4750  C CH2 . TRP B 2 433 ? 179.702 110.611 104.975 1.00 194.58 ? 455 TRP B CH2 1 
ATOM   4751  N N   . CYS B 2 434 ? 185.088 109.371 100.237 1.00 230.74 ? 456 CYS B N   1 
ATOM   4752  C CA  . CYS B 2 434 ? 186.222 110.240 100.514 1.00 230.74 ? 456 CYS B CA  1 
ATOM   4753  C C   . CYS B 2 434 ? 186.640 110.917 99.218  1.00 230.74 ? 456 CYS B C   1 
ATOM   4754  O O   . CYS B 2 434 ? 186.279 110.479 98.123  1.00 230.74 ? 456 CYS B O   1 
ATOM   4755  C CB  . CYS B 2 434 ? 187.397 109.467 101.123 1.00 230.74 ? 456 CYS B CB  1 
ATOM   4756  S SG  . CYS B 2 434 ? 188.373 108.509 99.942  1.00 230.74 ? 456 CYS B SG  1 
ATOM   4757  N N   . VAL B 2 435 ? 187.411 111.997 99.361  1.00 240.60 ? 457 VAL B N   1 
ATOM   4758  C CA  . VAL B 2 435 ? 187.874 112.741 98.198  1.00 240.60 ? 457 VAL B CA  1 
ATOM   4759  C C   . VAL B 2 435 ? 188.878 111.903 97.415  1.00 240.60 ? 457 VAL B C   1 
ATOM   4760  O O   . VAL B 2 435 ? 189.496 110.969 97.943  1.00 240.60 ? 457 VAL B O   1 
ATOM   4761  C CB  . VAL B 2 435 ? 188.485 114.089 98.621  1.00 240.60 ? 457 VAL B CB  1 
ATOM   4762  C CG1 . VAL B 2 435 ? 187.519 114.852 99.513  1.00 240.60 ? 457 VAL B CG1 1 
ATOM   4763  C CG2 . VAL B 2 435 ? 189.814 113.874 99.328  1.00 240.60 ? 457 VAL B CG2 1 
ATOM   4764  N N   . LEU B 2 436 ? 189.035 112.230 96.136  1.00 243.42 ? 458 LEU B N   1 
ATOM   4765  C CA  . LEU B 2 436 ? 189.981 111.550 95.263  1.00 243.42 ? 458 LEU B CA  1 
ATOM   4766  C C   . LEU B 2 436 ? 191.099 112.518 94.897  1.00 243.42 ? 458 LEU B C   1 
ATOM   4767  O O   . LEU B 2 436 ? 190.861 113.514 94.205  1.00 243.42 ? 458 LEU B O   1 
ATOM   4768  C CB  . LEU B 2 436 ? 189.287 111.024 94.007  1.00 243.42 ? 458 LEU B CB  1 
ATOM   4769  C CG  . LEU B 2 436 ? 190.136 110.148 93.084  1.00 243.42 ? 458 LEU B CG  1 
ATOM   4770  C CD1 . LEU B 2 436 ? 190.746 108.989 93.855  1.00 243.42 ? 458 LEU B CD1 1 
ATOM   4771  C CD2 . LEU B 2 436 ? 189.306 109.638 91.917  1.00 243.42 ? 458 LEU B CD2 1 
ATOM   4772  N N   . SER B 2 437 ? 192.311 112.226 95.363  1.00 249.37 ? 459 SER B N   1 
ATOM   4773  C CA  . SER B 2 437 ? 193.465 113.074 95.111  1.00 249.37 ? 459 SER B CA  1 
ATOM   4774  C C   . SER B 2 437 ? 194.686 112.205 94.855  1.00 249.37 ? 459 SER B C   1 
ATOM   4775  O O   . SER B 2 437 ? 194.897 111.201 95.540  1.00 249.37 ? 459 SER B O   1 
ATOM   4776  C CB  . SER B 2 437 ? 193.732 114.021 96.288  1.00 249.37 ? 459 SER B CB  1 
ATOM   4777  O OG  . SER B 2 437 ? 194.555 113.403 97.262  1.00 249.37 ? 459 SER B OG  1 
ATOM   4778  N N   . GLU B 2 438 ? 195.485 112.599 93.868  1.00 248.99 ? 460 GLU B N   1 
ATOM   4779  C CA  . GLU B 2 438 ? 196.702 111.883 93.515  1.00 248.99 ? 460 GLU B CA  1 
ATOM   4780  C C   . GLU B 2 438 ? 197.933 112.420 94.234  1.00 248.99 ? 460 GLU B C   1 
ATOM   4781  O O   . GLU B 2 438 ? 199.030 111.889 94.034  1.00 248.99 ? 460 GLU B O   1 
ATOM   4782  C CB  . GLU B 2 438 ? 196.927 111.935 92.000  1.00 248.99 ? 460 GLU B CB  1 
ATOM   4783  C CG  . GLU B 2 438 ? 197.210 113.328 91.456  1.00 248.99 ? 460 GLU B CG  1 
ATOM   4784  C CD  . GLU B 2 438 ? 195.946 114.127 91.204  1.00 248.99 ? 460 GLU B CD  1 
ATOM   4785  O OE1 . GLU B 2 438 ? 194.853 113.523 91.179  1.00 248.99 ? 460 GLU B OE1 1 
ATOM   4786  O OE2 . GLU B 2 438 ? 196.044 115.360 91.033  1.00 248.99 ? 460 GLU B OE2 1 
ATOM   4787  N N   . ASN B 2 439 ? 197.779 113.455 95.060  1.00 250.97 ? 461 ASN B N   1 
ATOM   4788  C CA  . ASN B 2 439 ? 198.895 114.023 95.803  1.00 250.97 ? 461 ASN B CA  1 
ATOM   4789  C C   . ASN B 2 439 ? 198.942 113.574 97.256  1.00 250.97 ? 461 ASN B C   1 
ATOM   4790  O O   . ASN B 2 439 ? 200.009 113.650 97.876  1.00 250.97 ? 461 ASN B O   1 
ATOM   4791  C CB  . ASN B 2 439 ? 198.840 115.555 95.754  1.00 250.97 ? 461 ASN B CB  1 
ATOM   4792  C CG  . ASN B 2 439 ? 198.569 116.084 94.360  1.00 250.97 ? 461 ASN B CG  1 
ATOM   4793  O OD1 . ASN B 2 439 ? 198.855 115.419 93.365  1.00 250.97 ? 461 ASN B OD1 1 
ATOM   4794  N ND2 . ASN B 2 439 ? 198.012 117.287 94.281  1.00 250.97 ? 461 ASN B ND2 1 
ATOM   4795  N N   . ALA B 2 440 ? 197.822 113.113 97.811  1.00 252.97 ? 462 ALA B N   1 
ATOM   4796  C CA  . ALA B 2 440 ? 197.768 112.677 99.199  1.00 252.97 ? 462 ALA B CA  1 
ATOM   4797  C C   . ALA B 2 440 ? 196.592 111.728 99.360  1.00 252.97 ? 462 ALA B C   1 
ATOM   4798  O O   . ALA B 2 440 ? 195.573 111.893 98.679  1.00 252.97 ? 462 ALA B O   1 
ATOM   4799  C CB  . ALA B 2 440 ? 197.628 113.872 100.153 1.00 252.97 ? 462 ALA B CB  1 
ATOM   4800  N N   . PRO B 2 441 ? 196.697 110.732 100.236 1.00 255.15 ? 463 PRO B N   1 
ATOM   4801  C CA  . PRO B 2 441 ? 195.571 109.818 100.451 1.00 255.15 ? 463 PRO B CA  1 
ATOM   4802  C C   . PRO B 2 441 ? 194.410 110.514 101.144 1.00 255.15 ? 463 PRO B C   1 
ATOM   4803  O O   . PRO B 2 441 ? 194.553 111.574 101.759 1.00 255.15 ? 463 PRO B O   1 
ATOM   4804  C CB  . PRO B 2 441 ? 196.167 108.718 101.335 1.00 255.15 ? 463 PRO B CB  1 
ATOM   4805  C CG  . PRO B 2 441 ? 197.320 109.370 102.020 1.00 255.15 ? 463 PRO B CG  1 
ATOM   4806  C CD  . PRO B 2 441 ? 197.874 110.364 101.040 1.00 255.15 ? 463 PRO B CD  1 
ATOM   4807  N N   . CYS B 2 442 ? 193.241 109.894 101.034 1.00 245.28 ? 464 CYS B N   1 
ATOM   4808  C CA  . CYS B 2 442 ? 192.018 110.443 101.598 1.00 245.28 ? 464 CYS B CA  1 
ATOM   4809  C C   . CYS B 2 442 ? 191.765 109.888 102.996 1.00 245.28 ? 464 CYS B C   1 
ATOM   4810  O O   . CYS B 2 442 ? 192.250 108.816 103.367 1.00 245.28 ? 464 CYS B O   1 
ATOM   4811  C CB  . CYS B 2 442 ? 190.824 110.139 100.692 1.00 245.28 ? 464 CYS B CB  1 
ATOM   4812  S SG  . CYS B 2 442 ? 190.224 108.433 100.778 1.00 245.28 ? 464 CYS B SG  1 
ATOM   4813  N N   . VAL B 2 443 ? 190.991 110.639 103.772 1.00 234.40 ? 465 VAL B N   1 
ATOM   4814  C CA  . VAL B 2 443 ? 190.597 110.230 105.115 1.00 234.40 ? 465 VAL B CA  1 
ATOM   4815  C C   . VAL B 2 443 ? 189.348 109.368 105.017 1.00 234.40 ? 465 VAL B C   1 
ATOM   4816  O O   . VAL B 2 443 ? 188.548 109.493 104.084 1.00 234.40 ? 465 VAL B O   1 
ATOM   4817  C CB  . VAL B 2 443 ? 190.375 111.455 106.028 1.00 234.40 ? 465 VAL B CB  1 
ATOM   4818  C CG1 . VAL B 2 443 ? 191.596 112.361 106.003 1.00 234.40 ? 465 VAL B CG1 1 
ATOM   4819  C CG2 . VAL B 2 443 ? 189.131 112.221 105.607 1.00 234.40 ? 465 VAL B CG2 1 
ATOM   4820  N N   . GLU B 2 444 ? 189.180 108.474 105.986 1.00 219.12 ? 466 GLU B N   1 
ATOM   4821  C CA  . GLU B 2 444 ? 188.082 107.516 105.977 1.00 219.12 ? 466 GLU B CA  1 
ATOM   4822  C C   . GLU B 2 444 ? 186.877 108.112 106.695 1.00 219.12 ? 466 GLU B C   1 
ATOM   4823  O O   . GLU B 2 444 ? 186.960 108.458 107.878 1.00 219.12 ? 466 GLU B O   1 
ATOM   4824  C CB  . GLU B 2 444 ? 188.500 106.198 106.630 1.00 219.12 ? 466 GLU B CB  1 
ATOM   4825  C CG  . GLU B 2 444 ? 189.455 105.334 105.803 1.00 219.12 ? 466 GLU B CG  1 
ATOM   4826  C CD  . GLU B 2 444 ? 190.749 106.040 105.442 1.00 219.12 ? 466 GLU B CD  1 
ATOM   4827  O OE1 . GLU B 2 444 ? 191.575 106.274 106.349 1.00 219.12 ? 466 GLU B OE1 1 
ATOM   4828  O OE2 . GLU B 2 444 ? 190.938 106.365 104.250 1.00 219.12 ? 466 GLU B OE2 1 
ATOM   4829  N N   . ASP B 2 445 ? 185.763 108.234 105.977 1.00 185.23 ? 467 ASP B N   1 
ATOM   4830  C CA  . ASP B 2 445 ? 184.500 108.689 106.538 1.00 185.23 ? 467 ASP B CA  1 
ATOM   4831  C C   . ASP B 2 445 ? 183.411 107.685 106.189 1.00 185.23 ? 467 ASP B C   1 
ATOM   4832  O O   . ASP B 2 445 ? 183.380 107.154 105.075 1.00 185.23 ? 467 ASP B O   1 
ATOM   4833  C CB  . ASP B 2 445 ? 184.127 110.080 106.015 1.00 185.23 ? 467 ASP B CB  1 
ATOM   4834  C CG  . ASP B 2 445 ? 183.076 110.762 106.869 1.00 185.23 ? 467 ASP B CG  1 
ATOM   4835  O OD1 . ASP B 2 445 ? 182.654 110.168 107.883 1.00 185.23 ? 467 ASP B OD1 1 
ATOM   4836  O OD2 . ASP B 2 445 ? 182.673 111.893 106.527 1.00 185.23 ? 467 ASP B OD2 1 
ATOM   4837  N N   . TRP B 2 446 ? 182.518 107.427 107.142 1.00 154.68 ? 468 TRP B N   1 
ATOM   4838  C CA  . TRP B 2 446 ? 181.494 106.407 106.980 1.00 154.68 ? 468 TRP B CA  1 
ATOM   4839  C C   . TRP B 2 446 ? 180.218 106.841 107.689 1.00 154.68 ? 468 TRP B C   1 
ATOM   4840  O O   . TRP B 2 446 ? 180.189 107.838 108.414 1.00 154.68 ? 468 TRP B O   1 
ATOM   4841  C CB  . TRP B 2 446 ? 181.969 105.051 107.518 1.00 154.68 ? 468 TRP B CB  1 
ATOM   4842  C CG  . TRP B 2 446 ? 182.208 105.049 108.997 1.00 154.68 ? 468 TRP B CG  1 
ATOM   4843  C CD1 . TRP B 2 446 ? 183.207 105.694 109.666 1.00 154.68 ? 468 TRP B CD1 1 
ATOM   4844  C CD2 . TRP B 2 446 ? 181.432 104.370 109.991 1.00 154.68 ? 468 TRP B CD2 1 
ATOM   4845  N NE1 . TRP B 2 446 ? 183.101 105.458 111.015 1.00 154.68 ? 468 TRP B NE1 1 
ATOM   4846  C CE2 . TRP B 2 446 ? 182.020 104.648 111.241 1.00 154.68 ? 468 TRP B CE2 1 
ATOM   4847  C CE3 . TRP B 2 446 ? 180.298 103.553 109.946 1.00 154.68 ? 468 TRP B CE3 1 
ATOM   4848  C CZ2 . TRP B 2 446 ? 181.512 104.139 112.435 1.00 154.68 ? 468 TRP B CZ2 1 
ATOM   4849  C CZ3 . TRP B 2 446 ? 179.796 103.048 111.133 1.00 154.68 ? 468 TRP B CZ3 1 
ATOM   4850  C CH2 . TRP B 2 446 ? 180.403 103.343 112.360 1.00 154.68 ? 468 TRP B CH2 1 
ATOM   4851  N N   . GLN B 2 447 ? 179.155 106.070 107.466 1.00 173.69 ? 469 GLN B N   1 
ATOM   4852  C CA  . GLN B 2 447 ? 177.870 106.302 108.111 1.00 173.69 ? 469 GLN B CA  1 
ATOM   4853  C C   . GLN B 2 447 ? 177.032 105.038 107.991 1.00 173.69 ? 469 GLN B C   1 
ATOM   4854  O O   . GLN B 2 447 ? 177.149 104.292 107.016 1.00 173.69 ? 469 GLN B O   1 
ATOM   4855  C CB  . GLN B 2 447 ? 177.134 107.497 107.497 1.00 173.69 ? 469 GLN B CB  1 
ATOM   4856  C CG  . GLN B 2 447 ? 177.042 107.462 105.983 1.00 173.69 ? 469 GLN B CG  1 
ATOM   4857  C CD  . GLN B 2 447 ? 176.363 108.692 105.416 1.00 173.69 ? 469 GLN B CD  1 
ATOM   4858  O OE1 . GLN B 2 447 ? 175.959 109.588 106.157 1.00 173.69 ? 469 GLN B OE1 1 
ATOM   4859  N NE2 . GLN B 2 447 ? 176.236 108.743 104.095 1.00 173.69 ? 469 GLN B NE2 1 
ATOM   4860  N N   . GLN B 2 448 ? 176.184 104.811 108.991 1.00 161.09 ? 470 GLN B N   1 
ATOM   4861  C CA  . GLN B 2 448 ? 175.366 103.610 109.074 1.00 161.09 ? 470 GLN B CA  1 
ATOM   4862  C C   . GLN B 2 448 ? 173.900 103.951 108.841 1.00 161.09 ? 470 GLN B C   1 
ATOM   4863  O O   . GLN B 2 448 ? 173.379 104.920 109.402 1.00 161.09 ? 470 GLN B O   1 
ATOM   4864  C CB  . GLN B 2 448 ? 175.532 102.928 110.436 1.00 161.09 ? 470 GLN B CB  1 
ATOM   4865  C CG  . GLN B 2 448 ? 174.554 101.791 110.686 1.00 161.09 ? 470 GLN B CG  1 
ATOM   4866  C CD  . GLN B 2 448 ? 174.786 101.103 112.015 1.00 161.09 ? 470 GLN B CD  1 
ATOM   4867  O OE1 . GLN B 2 448 ? 175.926 100.870 112.416 1.00 161.09 ? 470 GLN B OE1 1 
ATOM   4868  N NE2 . GLN B 2 448 ? 173.702 100.776 112.709 1.00 161.09 ? 470 GLN B NE2 1 
ATOM   4869  N N   . GLU B 2 449 ? 173.241 103.147 108.009 1.00 172.21 ? 471 GLU B N   1 
ATOM   4870  C CA  . GLU B 2 449 ? 171.828 103.310 107.709 1.00 172.21 ? 471 GLU B CA  1 
ATOM   4871  C C   . GLU B 2 449 ? 171.113 101.979 107.895 1.00 172.21 ? 471 GLU B C   1 
ATOM   4872  O O   . GLU B 2 449 ? 171.713 100.907 107.789 1.00 172.21 ? 471 GLU B O   1 
ATOM   4873  C CB  . GLU B 2 449 ? 171.610 103.831 106.282 1.00 172.21 ? 471 GLU B CB  1 
ATOM   4874  C CG  . GLU B 2 449 ? 171.955 105.300 106.095 1.00 172.21 ? 471 GLU B CG  1 
ATOM   4875  C CD  . GLU B 2 449 ? 173.448 105.541 105.981 1.00 172.21 ? 471 GLU B CD  1 
ATOM   4876  O OE1 . GLU B 2 449 ? 174.201 104.558 105.818 1.00 172.21 ? 471 GLU B OE1 1 
ATOM   4877  O OE2 . GLU B 2 449 ? 173.868 106.715 106.055 1.00 172.21 ? 471 GLU B OE2 1 
ATOM   4878  N N   . ASP B 2 450 ? 169.813 102.061 108.170 1.00 173.98 ? 472 ASP B N   1 
ATOM   4879  C CA  . ASP B 2 450 ? 169.014 100.870 108.411 1.00 173.98 ? 472 ASP B CA  1 
ATOM   4880  C C   . ASP B 2 450 ? 168.784 100.112 107.103 1.00 173.98 ? 472 ASP B C   1 
ATOM   4881  O O   . ASP B 2 450 ? 169.191 100.538 106.019 1.00 173.98 ? 472 ASP B O   1 
ATOM   4882  C CB  . ASP B 2 450 ? 167.688 101.246 109.068 1.00 173.98 ? 472 ASP B CB  1 
ATOM   4883  C CG  . ASP B 2 450 ? 167.859 101.703 110.504 1.00 173.98 ? 472 ASP B CG  1 
ATOM   4884  O OD1 . ASP B 2 450 ? 168.736 101.154 111.204 1.00 173.98 ? 472 ASP B OD1 1 
ATOM   4885  O OD2 . ASP B 2 450 ? 167.116 102.610 110.934 1.00 173.98 ? 472 ASP B OD2 1 
ATOM   4886  N N   . ALA B 2 451 ? 168.113 98.963  107.214 1.00 183.34 ? 473 ALA B N   1 
ATOM   4887  C CA  . ALA B 2 451 ? 167.866 98.125  106.047 1.00 183.34 ? 473 ALA B CA  1 
ATOM   4888  C C   . ALA B 2 451 ? 166.701 98.633  105.206 1.00 183.34 ? 473 ALA B C   1 
ATOM   4889  O O   . ALA B 2 451 ? 166.640 98.344  104.005 1.00 183.34 ? 473 ALA B O   1 
ATOM   4890  C CB  . ALA B 2 451 ? 167.606 96.682  106.480 1.00 183.34 ? 473 ALA B CB  1 
ATOM   4891  N N   . THR B 2 452 ? 165.775 99.380  105.808 1.00 187.97 ? 474 THR B N   1 
ATOM   4892  C CA  . THR B 2 452 ? 164.612 99.870  105.079 1.00 187.97 ? 474 THR B CA  1 
ATOM   4893  C C   . THR B 2 452 ? 164.931 101.059 104.182 1.00 187.97 ? 474 THR B C   1 
ATOM   4894  O O   . THR B 2 452 ? 164.162 101.342 103.257 1.00 187.97 ? 474 THR B O   1 
ATOM   4895  C CB  . THR B 2 452 ? 163.500 100.258 106.056 1.00 187.97 ? 474 THR B CB  1 
ATOM   4896  O OG1 . THR B 2 452 ? 163.804 101.526 106.650 1.00 187.97 ? 474 THR B OG1 1 
ATOM   4897  C CG2 . THR B 2 452 ? 163.367 99.211  107.153 1.00 187.97 ? 474 THR B CG2 1 
ATOM   4898  N N   . VAL B 2 453 ? 166.037 101.753 104.428 1.00 196.04 ? 475 VAL B N   1 
ATOM   4899  C CA  . VAL B 2 453 ? 166.387 102.937 103.651 1.00 196.04 ? 475 VAL B CA  1 
ATOM   4900  C C   . VAL B 2 453 ? 167.123 102.508 102.389 1.00 196.04 ? 475 VAL B C   1 
ATOM   4901  O O   . VAL B 2 453 ? 168.078 101.724 102.446 1.00 196.04 ? 475 VAL B O   1 
ATOM   4902  C CB  . VAL B 2 453 ? 167.237 103.905 104.488 1.00 196.04 ? 475 VAL B CB  1 
ATOM   4903  C CG1 . VAL B 2 453 ? 167.681 105.090 103.644 1.00 196.04 ? 475 VAL B CG1 1 
ATOM   4904  C CG2 . VAL B 2 453 ? 166.459 104.373 105.708 1.00 196.04 ? 475 VAL B CG2 1 
ATOM   4905  N N   . ASN B 2 454 ? 166.677 103.021 101.241 1.00 206.03 ? 476 ASN B N   1 
ATOM   4906  C CA  . ASN B 2 454 ? 167.313 102.738 99.964  1.00 206.03 ? 476 ASN B CA  1 
ATOM   4907  C C   . ASN B 2 454 ? 167.857 103.974 99.263  1.00 206.03 ? 476 ASN B C   1 
ATOM   4908  O O   . ASN B 2 454 ? 168.525 103.832 98.233  1.00 206.03 ? 476 ASN B O   1 
ATOM   4909  C CB  . ASN B 2 454 ? 166.331 102.022 99.022  1.00 206.03 ? 476 ASN B CB  1 
ATOM   4910  C CG  . ASN B 2 454 ? 164.969 102.687 98.984  1.00 206.03 ? 476 ASN B CG  1 
ATOM   4911  O OD1 . ASN B 2 454 ? 164.812 103.835 99.399  1.00 206.03 ? 476 ASN B OD1 1 
ATOM   4912  N ND2 . ASN B 2 454 ? 163.973 101.965 98.483  1.00 206.03 ? 476 ASN B ND2 1 
ATOM   4913  N N   . ARG B 2 455 ? 167.594 105.172 99.781  1.00 211.01 ? 477 ARG B N   1 
ATOM   4914  C CA  . ARG B 2 455 ? 168.092 106.400 99.176  1.00 211.01 ? 477 ARG B CA  1 
ATOM   4915  C C   . ARG B 2 455 ? 168.264 107.452 100.261 1.00 211.01 ? 477 ARG B C   1 
ATOM   4916  O O   . ARG B 2 455 ? 167.317 107.746 100.996 1.00 211.01 ? 477 ARG B O   1 
ATOM   4917  C CB  . ARG B 2 455 ? 167.141 106.909 98.087  1.00 211.01 ? 477 ARG B CB  1 
ATOM   4918  C CG  . ARG B 2 455 ? 167.645 108.140 97.352  1.00 211.01 ? 477 ARG B CG  1 
ATOM   4919  C CD  . ARG B 2 455 ? 166.545 108.773 96.516  1.00 211.01 ? 477 ARG B CD  1 
ATOM   4920  N NE  . ARG B 2 455 ? 165.920 107.810 95.614  1.00 211.01 ? 477 ARG B NE  1 
ATOM   4921  C CZ  . ARG B 2 455 ? 164.900 108.093 94.809  1.00 211.01 ? 477 ARG B CZ  1 
ATOM   4922  N NH1 . ARG B 2 455 ? 164.386 109.315 94.791  1.00 211.01 ? 477 ARG B NH1 1 
ATOM   4923  N NH2 . ARG B 2 455 ? 164.394 107.153 94.022  1.00 211.01 ? 477 ARG B NH2 1 
ATOM   4924  N N   . THR B 2 456 ? 169.467 108.012 100.354 1.00 210.71 ? 478 THR B N   1 
ATOM   4925  C CA  . THR B 2 456 ? 169.765 109.028 101.354 1.00 210.71 ? 478 THR B CA  1 
ATOM   4926  C C   . THR B 2 456 ? 170.914 109.887 100.846 1.00 210.71 ? 478 THR B C   1 
ATOM   4927  O O   . THR B 2 456 ? 171.525 109.598 99.814  1.00 210.71 ? 478 THR B O   1 
ATOM   4928  C CB  . THR B 2 456 ? 170.109 108.399 102.708 1.00 210.71 ? 478 THR B CB  1 
ATOM   4929  O OG1 . THR B 2 456 ? 170.515 109.424 103.625 1.00 210.71 ? 478 THR B OG1 1 
ATOM   4930  C CG2 . THR B 2 456 ? 171.235 107.388 102.555 1.00 210.71 ? 478 THR B CG2 1 
ATOM   4931  N N   . HIS B 2 457 ? 171.199 110.953 101.588 1.00 201.91 ? 479 HIS B N   1 
ATOM   4932  C CA  . HIS B 2 457 ? 172.263 111.886 101.254 1.00 201.91 ? 479 HIS B CA  1 
ATOM   4933  C C   . HIS B 2 457 ? 173.437 111.712 102.208 1.00 201.91 ? 479 HIS B C   1 
ATOM   4934  O O   . HIS B 2 457 ? 173.306 111.151 103.300 1.00 201.91 ? 479 HIS B O   1 
ATOM   4935  C CB  . HIS B 2 457 ? 171.760 113.333 101.300 1.00 201.91 ? 479 HIS B CB  1 
ATOM   4936  C CG  . HIS B 2 457 ? 171.435 113.817 102.678 1.00 201.91 ? 479 HIS B CG  1 
ATOM   4937  N ND1 . HIS B 2 457 ? 170.194 113.648 103.253 1.00 201.91 ? 479 HIS B ND1 1 
ATOM   4938  C CD2 . HIS B 2 457 ? 172.189 114.468 103.596 1.00 201.91 ? 479 HIS B CD2 1 
ATOM   4939  C CE1 . HIS B 2 457 ? 170.197 114.172 104.466 1.00 201.91 ? 479 HIS B CE1 1 
ATOM   4940  N NE2 . HIS B 2 457 ? 171.396 114.676 104.698 1.00 201.91 ? 479 HIS B NE2 1 
ATOM   4941  N N   . LEU B 2 458 ? 174.596 112.206 101.779 1.00 192.18 ? 480 LEU B N   1 
ATOM   4942  C CA  . LEU B 2 458 ? 175.813 112.107 102.575 1.00 192.18 ? 480 LEU B CA  1 
ATOM   4943  C C   . LEU B 2 458 ? 175.765 113.119 103.713 1.00 192.18 ? 480 LEU B C   1 
ATOM   4944  O O   . LEU B 2 458 ? 175.652 114.326 103.475 1.00 192.18 ? 480 LEU B O   1 
ATOM   4945  C CB  . LEU B 2 458 ? 177.041 112.338 101.698 1.00 192.18 ? 480 LEU B CB  1 
ATOM   4946  C CG  . LEU B 2 458 ? 177.152 111.463 100.448 1.00 192.18 ? 480 LEU B CG  1 
ATOM   4947  C CD1 . LEU B 2 458 ? 178.450 111.746 99.707  1.00 192.18 ? 480 LEU B CD1 1 
ATOM   4948  C CD2 . LEU B 2 458 ? 177.048 109.990 100.811 1.00 192.18 ? 480 LEU B CD2 1 
ATOM   4949  N N   . ARG B 2 459 ? 175.852 112.627 104.948 1.00 185.28 ? 481 ARG B N   1 
ATOM   4950  C CA  . ARG B 2 459 ? 175.827 113.483 106.134 1.00 185.28 ? 481 ARG B CA  1 
ATOM   4951  C C   . ARG B 2 459 ? 177.266 113.817 106.506 1.00 185.28 ? 481 ARG B C   1 
ATOM   4952  O O   . ARG B 2 459 ? 177.940 113.070 107.216 1.00 185.28 ? 481 ARG B O   1 
ATOM   4953  C CB  . ARG B 2 459 ? 175.093 112.798 107.280 1.00 185.28 ? 481 ARG B CB  1 
ATOM   4954  C CG  . ARG B 2 459 ? 173.810 112.097 106.864 1.00 185.28 ? 481 ARG B CG  1 
ATOM   4955  C CD  . ARG B 2 459 ? 173.077 111.527 108.068 1.00 185.28 ? 481 ARG B CD  1 
ATOM   4956  N NE  . ARG B 2 459 ? 173.986 110.872 109.003 1.00 185.28 ? 481 ARG B NE  1 
ATOM   4957  C CZ  . ARG B 2 459 ? 174.392 109.611 108.892 1.00 185.28 ? 481 ARG B CZ  1 
ATOM   4958  N NH1 . ARG B 2 459 ? 173.970 108.863 107.882 1.00 185.28 ? 481 ARG B NH1 1 
ATOM   4959  N NH2 . ARG B 2 459 ? 175.221 109.098 109.791 1.00 185.28 ? 481 ARG B NH2 1 
ATOM   4960  N N   . GLY B 2 460 ? 177.741 114.956 106.019 1.00 198.18 ? 482 GLY B N   1 
ATOM   4961  C CA  . GLY B 2 460 ? 179.099 115.379 106.307 1.00 198.18 ? 482 GLY B CA  1 
ATOM   4962  C C   . GLY B 2 460 ? 179.373 116.727 105.680 1.00 198.18 ? 482 GLY B C   1 
ATOM   4963  O O   . GLY B 2 460 ? 178.519 117.316 105.010 1.00 198.18 ? 482 GLY B O   1 
ATOM   4964  N N   . ARG B 2 461 ? 180.592 117.211 105.911 1.00 204.06 ? 483 ARG B N   1 
ATOM   4965  C CA  . ARG B 2 461 ? 181.033 118.500 105.378 1.00 204.06 ? 483 ARG B CA  1 
ATOM   4966  C C   . ARG B 2 461 ? 181.780 118.245 104.076 1.00 204.06 ? 483 ARG B C   1 
ATOM   4967  O O   . ARG B 2 461 ? 182.991 118.017 104.060 1.00 204.06 ? 483 ARG B O   1 
ATOM   4968  C CB  . ARG B 2 461 ? 181.899 119.237 106.393 1.00 204.06 ? 483 ARG B CB  1 
ATOM   4969  C CG  . ARG B 2 461 ? 182.337 120.625 105.948 1.00 204.06 ? 483 ARG B CG  1 
ATOM   4970  C CD  . ARG B 2 461 ? 181.147 121.557 105.781 1.00 204.06 ? 483 ARG B CD  1 
ATOM   4971  N NE  . ARG B 2 461 ? 180.677 121.608 104.399 1.00 204.06 ? 483 ARG B NE  1 
ATOM   4972  C CZ  . ARG B 2 461 ? 179.603 122.280 104.000 1.00 204.06 ? 483 ARG B CZ  1 
ATOM   4973  N NH1 . ARG B 2 461 ? 178.882 122.964 104.878 1.00 204.06 ? 483 ARG B NH1 1 
ATOM   4974  N NH2 . ARG B 2 461 ? 179.249 122.270 102.722 1.00 204.06 ? 483 ARG B NH2 1 
ATOM   4975  N N   . LEU B 2 462 ? 181.047 118.283 102.969 1.00 208.11 ? 484 LEU B N   1 
ATOM   4976  C CA  . LEU B 2 462 ? 181.623 118.050 101.655 1.00 208.11 ? 484 LEU B CA  1 
ATOM   4977  C C   . LEU B 2 462 ? 182.135 119.355 101.053 1.00 208.11 ? 484 LEU B C   1 
ATOM   4978  O O   . LEU B 2 462 ? 181.710 120.452 101.424 1.00 208.11 ? 484 LEU B O   1 
ATOM   4979  C CB  . LEU B 2 462 ? 180.595 117.411 100.719 1.00 208.11 ? 484 LEU B CB  1 
ATOM   4980  C CG  . LEU B 2 462 ? 180.570 115.883 100.657 1.00 208.11 ? 484 LEU B CG  1 
ATOM   4981  C CD1 . LEU B 2 462 ? 180.065 115.290 101.964 1.00 208.11 ? 484 LEU B CD1 1 
ATOM   4982  C CD2 . LEU B 2 462 ? 179.722 115.410 99.486  1.00 208.11 ? 484 LEU B CD2 1 
ATOM   4983  N N   . LEU B 2 463 ? 183.065 119.220 100.112 1.00 218.53 ? 485 LEU B N   1 
ATOM   4984  C CA  . LEU B 2 463 ? 183.645 120.351 99.404  1.00 218.53 ? 485 LEU B CA  1 
ATOM   4985  C C   . LEU B 2 463 ? 183.274 120.274 97.930  1.00 218.53 ? 485 LEU B C   1 
ATOM   4986  O O   . LEU B 2 463 ? 183.253 119.190 97.340  1.00 218.53 ? 485 LEU B O   1 
ATOM   4987  C CB  . LEU B 2 463 ? 185.169 120.382 99.560  1.00 218.53 ? 485 LEU B CB  1 
ATOM   4988  C CG  . LEU B 2 463 ? 185.700 120.486 100.991 1.00 218.53 ? 485 LEU B CG  1 
ATOM   4989  C CD1 . LEU B 2 463 ? 187.220 120.549 100.996 1.00 218.53 ? 485 LEU B CD1 1 
ATOM   4990  C CD2 . LEU B 2 463 ? 185.107 121.696 101.697 1.00 218.53 ? 485 LEU B CD2 1 
ATOM   4991  N N   . GLU B 2 464 ? 182.981 121.430 97.342  1.00 224.54 ? 486 GLU B N   1 
ATOM   4992  C CA  . GLU B 2 464 ? 182.595 121.488 95.942  1.00 224.54 ? 486 GLU B CA  1 
ATOM   4993  C C   . GLU B 2 464 ? 183.816 121.333 95.040  1.00 224.54 ? 486 GLU B C   1 
ATOM   4994  O O   . GLU B 2 464 ? 184.964 121.494 95.466  1.00 224.54 ? 486 GLU B O   1 
ATOM   4995  C CB  . GLU B 2 464 ? 181.879 122.804 95.634  1.00 224.54 ? 486 GLU B CB  1 
ATOM   4996  C CG  . GLU B 2 464 ? 182.729 124.046 95.856  1.00 224.54 ? 486 GLU B CG  1 
ATOM   4997  C CD  . GLU B 2 464 ? 182.714 124.515 97.298  1.00 224.54 ? 486 GLU B CD  1 
ATOM   4998  O OE1 . GLU B 2 464 ? 181.944 123.949 98.102  1.00 224.54 ? 486 GLU B OE1 1 
ATOM   4999  O OE2 . GLU B 2 464 ? 183.474 125.449 97.628  1.00 224.54 ? 486 GLU B OE2 1 
ATOM   5000  N N   . SER B 2 465 ? 183.547 121.011 93.772  1.00 233.47 ? 487 SER B N   1 
ATOM   5001  C CA  . SER B 2 465 ? 184.584 120.820 92.755  1.00 233.47 ? 487 SER B CA  1 
ATOM   5002  C C   . SER B 2 465 ? 185.591 119.748 93.164  1.00 233.47 ? 487 SER B C   1 
ATOM   5003  O O   . SER B 2 465 ? 186.775 119.834 92.830  1.00 233.47 ? 487 SER B O   1 
ATOM   5004  C CB  . SER B 2 465 ? 185.302 122.135 92.438  1.00 233.47 ? 487 SER B CB  1 
ATOM   5005  O OG  . SER B 2 465 ? 184.383 123.128 92.015  1.00 233.47 ? 487 SER B OG  1 
ATOM   5006  N N   . LYS B 2 466 ? 185.129 118.731 93.888  1.00 234.62 ? 488 LYS B N   1 
ATOM   5007  C CA  . LYS B 2 466 ? 185.976 117.639 94.342  1.00 234.62 ? 488 LYS B CA  1 
ATOM   5008  C C   . LYS B 2 466 ? 185.283 116.313 94.070  1.00 234.62 ? 488 LYS B C   1 
ATOM   5009  O O   . LYS B 2 466 ? 184.079 116.172 94.306  1.00 234.62 ? 488 LYS B O   1 
ATOM   5010  C CB  . LYS B 2 466 ? 186.300 117.765 95.836  1.00 234.62 ? 488 LYS B CB  1 
ATOM   5011  C CG  . LYS B 2 466 ? 187.195 118.943 96.179  1.00 234.62 ? 488 LYS B CG  1 
ATOM   5012  C CD  . LYS B 2 466 ? 188.532 118.844 95.466  1.00 234.62 ? 488 LYS B CD  1 
ATOM   5013  C CE  . LYS B 2 466 ? 189.417 120.038 95.781  1.00 234.62 ? 488 LYS B CE  1 
ATOM   5014  N NZ  . LYS B 2 466 ? 190.727 119.958 95.079  1.00 234.62 ? 488 LYS B NZ  1 
ATOM   5015  N N   . CYS B 2 467 ? 186.046 115.345 93.570  1.00 239.09 ? 489 CYS B N   1 
ATOM   5016  C CA  . CYS B 2 467 ? 185.505 114.026 93.275  1.00 239.09 ? 489 CYS B CA  1 
ATOM   5017  C C   . CYS B 2 467 ? 185.478 113.178 94.540  1.00 239.09 ? 489 CYS B C   1 
ATOM   5018  O O   . CYS B 2 467 ? 186.503 113.011 95.209  1.00 239.09 ? 489 CYS B O   1 
ATOM   5019  C CB  . CYS B 2 467 ? 186.333 113.336 92.193  1.00 239.09 ? 489 CYS B CB  1 
ATOM   5020  S SG  . CYS B 2 467 ? 186.009 111.567 92.018  1.00 239.09 ? 489 CYS B SG  1 
ATOM   5021  N N   . TYR B 2 468 ? 184.304 112.643 94.865  1.00 230.15 ? 490 TYR B N   1 
ATOM   5022  C CA  . TYR B 2 468 ? 184.106 111.828 96.059  1.00 230.15 ? 490 TYR B CA  1 
ATOM   5023  C C   . TYR B 2 468 ? 183.863 110.387 95.628  1.00 230.15 ? 490 TYR B C   1 
ATOM   5024  O O   . TYR B 2 468 ? 182.862 110.090 94.968  1.00 230.15 ? 490 TYR B O   1 
ATOM   5025  C CB  . TYR B 2 468 ? 182.942 112.360 96.893  1.00 230.15 ? 490 TYR B CB  1 
ATOM   5026  C CG  . TYR B 2 468 ? 183.276 113.610 97.675  1.00 230.15 ? 490 TYR B CG  1 
ATOM   5027  C CD1 . TYR B 2 468 ? 183.630 113.541 99.016  1.00 230.15 ? 490 TYR B CD1 1 
ATOM   5028  C CD2 . TYR B 2 468 ? 183.240 114.860 97.071  1.00 230.15 ? 490 TYR B CD2 1 
ATOM   5029  C CE1 . TYR B 2 468 ? 183.936 114.681 99.734  1.00 230.15 ? 490 TYR B CE1 1 
ATOM   5030  C CE2 . TYR B 2 468 ? 183.545 116.006 97.781  1.00 230.15 ? 490 TYR B CE2 1 
ATOM   5031  C CZ  . TYR B 2 468 ? 183.892 115.910 99.112  1.00 230.15 ? 490 TYR B CZ  1 
ATOM   5032  O OH  . TYR B 2 468 ? 184.197 117.048 99.822  1.00 230.15 ? 490 TYR B OH  1 
ATOM   5033  N N   . GLN B 2 469 ? 184.780 109.497 96.001  1.00 223.30 ? 491 GLN B N   1 
ATOM   5034  C CA  . GLN B 2 469 ? 184.674 108.078 95.669  1.00 223.30 ? 491 GLN B CA  1 
ATOM   5035  C C   . GLN B 2 469 ? 183.713 107.423 96.653  1.00 223.30 ? 491 GLN B C   1 
ATOM   5036  O O   . GLN B 2 469 ? 184.078 107.124 97.792  1.00 223.30 ? 491 GLN B O   1 
ATOM   5037  C CB  . GLN B 2 469 ? 186.046 107.417 95.706  1.00 223.30 ? 491 GLN B CB  1 
ATOM   5038  C CG  . GLN B 2 469 ? 186.025 105.923 95.433  1.00 223.30 ? 491 GLN B CG  1 
ATOM   5039  C CD  . GLN B 2 469 ? 187.415 105.320 95.382  1.00 223.30 ? 491 GLN B CD  1 
ATOM   5040  O OE1 . GLN B 2 469 ? 188.415 106.024 95.526  1.00 223.30 ? 491 GLN B OE1 1 
ATOM   5041  N NE2 . GLN B 2 469 ? 187.484 104.011 95.175  1.00 223.30 ? 491 GLN B NE2 1 
ATOM   5042  N N   . ILE B 2 470 ? 182.480 107.196 96.213  1.00 217.02 ? 492 ILE B N   1 
ATOM   5043  C CA  . ILE B 2 470 ? 181.442 106.625 97.064  1.00 217.02 ? 492 ILE B CA  1 
ATOM   5044  C C   . ILE B 2 470 ? 181.460 105.108 96.930  1.00 217.02 ? 492 ILE B C   1 
ATOM   5045  O O   . ILE B 2 470 ? 181.578 104.568 95.823  1.00 217.02 ? 492 ILE B O   1 
ATOM   5046  C CB  . ILE B 2 470 ? 180.061 107.204 96.710  1.00 217.02 ? 492 ILE B CB  1 
ATOM   5047  C CG1 . ILE B 2 470 ? 179.710 106.927 95.246  1.00 217.02 ? 492 ILE B CG1 1 
ATOM   5048  C CG2 . ILE B 2 470 ? 180.021 108.697 96.994  1.00 217.02 ? 492 ILE B CG2 1 
ATOM   5049  C CD1 . ILE B 2 470 ? 178.280 107.262 94.886  1.00 217.02 ? 492 ILE B CD1 1 
ATOM   5050  N N   . THR B 2 471 ? 181.368 104.417 98.065  1.00 208.55 ? 493 THR B N   1 
ATOM   5051  C CA  . THR B 2 471 ? 181.333 102.961 98.108  1.00 208.55 ? 493 THR B CA  1 
ATOM   5052  C C   . THR B 2 471 ? 180.222 102.522 99.049  1.00 208.55 ? 493 THR B C   1 
ATOM   5053  O O   . THR B 2 471 ? 180.114 103.033 100.169 1.00 208.55 ? 493 THR B O   1 
ATOM   5054  C CB  . THR B 2 471 ? 182.674 102.374 98.570  1.00 208.55 ? 493 THR B CB  1 
ATOM   5055  O OG1 . THR B 2 471 ? 183.027 102.922 99.846  1.00 208.55 ? 493 THR B OG1 1 
ATOM   5056  C CG2 . THR B 2 471 ? 183.776 102.683 97.564  1.00 208.55 ? 493 THR B CG2 1 
ATOM   5057  N N   . VAL B 2 472 ? 179.399 101.580 98.595  1.00 203.53 ? 494 VAL B N   1 
ATOM   5058  C CA  . VAL B 2 472 ? 178.289 101.051 99.377  1.00 203.53 ? 494 VAL B CA  1 
ATOM   5059  C C   . VAL B 2 472 ? 178.528 99.568  99.616  1.00 203.53 ? 494 VAL B C   1 
ATOM   5060  O O   . VAL B 2 472 ? 178.845 98.822  98.683  1.00 203.53 ? 494 VAL B O   1 
ATOM   5061  C CB  . VAL B 2 472 ? 176.936 101.282 98.670  1.00 203.53 ? 494 VAL B CB  1 
ATOM   5062  C CG1 . VAL B 2 472 ? 175.806 100.630 99.453  1.00 203.53 ? 494 VAL B CG1 1 
ATOM   5063  C CG2 . VAL B 2 472 ? 176.681 102.770 98.488  1.00 203.53 ? 494 VAL B CG2 1 
ATOM   5064  N N   . THR B 2 473 ? 178.377 99.143  100.870 1.00 197.24 ? 495 THR B N   1 
ATOM   5065  C CA  . THR B 2 473 ? 178.596 97.749  101.236 1.00 197.24 ? 495 THR B CA  1 
ATOM   5066  C C   . THR B 2 473 ? 177.442 97.236  102.089 1.00 197.24 ? 495 THR B C   1 
ATOM   5067  O O   . THR B 2 473 ? 177.255 97.694  103.224 1.00 197.24 ? 495 THR B O   1 
ATOM   5068  C CB  . THR B 2 473 ? 179.918 97.586  101.988 1.00 197.24 ? 495 THR B CB  1 
ATOM   5069  O OG1 . THR B 2 473 ? 180.072 98.656  102.929 1.00 197.24 ? 495 THR B OG1 1 
ATOM   5070  C CG2 . THR B 2 473 ? 181.090 97.597  101.017 1.00 197.24 ? 495 THR B CG2 1 
ATOM   5071  N N   . PRO B 2 474 ? 176.649 96.295  101.583 1.00 198.96 ? 496 PRO B N   1 
ATOM   5072  C CA  . PRO B 2 474 ? 175.567 95.732  102.396 1.00 198.96 ? 496 PRO B CA  1 
ATOM   5073  C C   . PRO B 2 474 ? 176.102 94.764  103.439 1.00 198.96 ? 496 PRO B C   1 
ATOM   5074  O O   . PRO B 2 474 ? 177.103 94.074  103.230 1.00 198.96 ? 496 PRO B O   1 
ATOM   5075  C CB  . PRO B 2 474 ? 174.691 95.011  101.367 1.00 198.96 ? 496 PRO B CB  1 
ATOM   5076  C CG  . PRO B 2 474 ? 175.642 94.636  100.280 1.00 198.96 ? 496 PRO B CG  1 
ATOM   5077  C CD  . PRO B 2 474 ? 176.669 95.737  100.220 1.00 198.96 ? 496 PRO B CD  1 
ATOM   5078  N N   . VAL B 2 475 ? 175.416 94.721  104.578 1.00 189.63 ? 497 VAL B N   1 
ATOM   5079  C CA  . VAL B 2 475 ? 175.791 93.871  105.702 1.00 189.63 ? 497 VAL B CA  1 
ATOM   5080  C C   . VAL B 2 475 ? 174.715 92.809  105.876 1.00 189.63 ? 497 VAL B C   1 
ATOM   5081  O O   . VAL B 2 475 ? 173.534 93.134  106.053 1.00 189.63 ? 497 VAL B O   1 
ATOM   5082  C CB  . VAL B 2 475 ? 175.974 94.684  106.992 1.00 189.63 ? 497 VAL B CB  1 
ATOM   5083  C CG1 . VAL B 2 475 ? 176.376 93.771  108.140 1.00 189.63 ? 497 VAL B CG1 1 
ATOM   5084  C CG2 . VAL B 2 475 ? 177.007 95.779  106.786 1.00 189.63 ? 497 VAL B CG2 1 
ATOM   5085  N N   . PHE B 2 476 ? 175.120 91.544  105.826 1.00 200.40 ? 498 PHE B N   1 
ATOM   5086  C CA  . PHE B 2 476 ? 174.220 90.423  106.036 1.00 200.40 ? 498 PHE B CA  1 
ATOM   5087  C C   . PHE B 2 476 ? 174.378 89.890  107.458 1.00 200.40 ? 498 PHE B C   1 
ATOM   5088  O O   . PHE B 2 476 ? 175.099 90.450  108.287 1.00 200.40 ? 498 PHE B O   1 
ATOM   5089  C CB  . PHE B 2 476 ? 174.480 89.322  105.005 1.00 200.40 ? 498 PHE B CB  1 
ATOM   5090  C CG  . PHE B 2 476 ? 174.197 89.735  103.590 1.00 200.40 ? 498 PHE B CG  1 
ATOM   5091  C CD1 . PHE B 2 476 ? 172.924 89.613  103.060 1.00 200.40 ? 498 PHE B CD1 1 
ATOM   5092  C CD2 . PHE B 2 476 ? 175.206 90.240  102.787 1.00 200.40 ? 498 PHE B CD2 1 
ATOM   5093  C CE1 . PHE B 2 476 ? 172.661 89.989  101.758 1.00 200.40 ? 498 PHE B CE1 1 
ATOM   5094  C CE2 . PHE B 2 476 ? 174.949 90.618  101.483 1.00 200.40 ? 498 PHE B CE2 1 
ATOM   5095  C CZ  . PHE B 2 476 ? 173.674 90.493  100.968 1.00 200.40 ? 498 PHE B CZ  1 
ATOM   5096  N N   . ALA B 2 477 ? 173.687 88.786  107.741 1.00 196.76 ? 499 ALA B N   1 
ATOM   5097  C CA  . ALA B 2 477 ? 173.783 88.156  109.051 1.00 196.76 ? 499 ALA B CA  1 
ATOM   5098  C C   . ALA B 2 477 ? 175.056 87.340  109.218 1.00 196.76 ? 499 ALA B C   1 
ATOM   5099  O O   . ALA B 2 477 ? 175.441 87.044  110.355 1.00 196.76 ? 499 ALA B O   1 
ATOM   5100  C CB  . ALA B 2 477 ? 172.564 87.264  109.297 1.00 196.76 ? 499 ALA B CB  1 
ATOM   5101  N N   . THR B 2 478 ? 175.716 86.972  108.121 1.00 199.00 ? 500 THR B N   1 
ATOM   5102  C CA  . THR B 2 478 ? 176.930 86.169  108.169 1.00 199.00 ? 500 THR B CA  1 
ATOM   5103  C C   . THR B 2 478 ? 178.166 86.921  107.695 1.00 199.00 ? 500 THR B C   1 
ATOM   5104  O O   . THR B 2 478 ? 179.261 86.349  107.700 1.00 199.00 ? 500 THR B O   1 
ATOM   5105  C CB  . THR B 2 478 ? 176.755 84.894  107.335 1.00 199.00 ? 500 THR B CB  1 
ATOM   5106  O OG1 . THR B 2 478 ? 176.089 85.213  106.106 1.00 199.00 ? 500 THR B OG1 1 
ATOM   5107  C CG2 . THR B 2 478 ? 175.933 83.867  108.099 1.00 199.00 ? 500 THR B CG2 1 
ATOM   5108  N N   . GLY B 2 479 ? 178.025 88.179  107.285 1.00 204.11 ? 501 GLY B N   1 
ATOM   5109  C CA  . GLY B 2 479 ? 179.148 88.959  106.824 1.00 204.11 ? 501 GLY B CA  1 
ATOM   5110  C C   . GLY B 2 479 ? 178.744 90.014  105.816 1.00 204.11 ? 501 GLY B C   1 
ATOM   5111  O O   . GLY B 2 479 ? 177.596 90.067  105.363 1.00 204.11 ? 501 GLY B O   1 
ATOM   5112  N N   . PRO B 2 480 ? 179.684 90.879  105.445 1.00 206.42 ? 502 PRO B N   1 
ATOM   5113  C CA  . PRO B 2 480 ? 179.374 91.934  104.476 1.00 206.42 ? 502 PRO B CA  1 
ATOM   5114  C C   . PRO B 2 480 ? 179.185 91.373  103.075 1.00 206.42 ? 502 PRO B C   1 
ATOM   5115  O O   . PRO B 2 480 ? 179.604 90.260  102.752 1.00 206.42 ? 502 PRO B O   1 
ATOM   5116  C CB  . PRO B 2 480 ? 180.600 92.851  104.546 1.00 206.42 ? 502 PRO B CB  1 
ATOM   5117  C CG  . PRO B 2 480 ? 181.705 91.958  104.998 1.00 206.42 ? 502 PRO B CG  1 
ATOM   5118  C CD  . PRO B 2 480 ? 181.077 90.949  105.920 1.00 206.42 ? 502 PRO B CD  1 
ATOM   5119  N N   . GLY B 2 481 ? 178.537 92.172  102.238 1.00 212.94 ? 503 GLY B N   1 
ATOM   5120  C CA  . GLY B 2 481 ? 178.267 91.812  100.861 1.00 212.94 ? 503 GLY B CA  1 
ATOM   5121  C C   . GLY B 2 481 ? 179.323 92.317  99.903  1.00 212.94 ? 503 GLY B C   1 
ATOM   5122  O O   . GLY B 2 481 ? 180.511 92.396  100.232 1.00 212.94 ? 503 GLY B O   1 
ATOM   5123  N N   . GLY B 2 482 ? 178.881 92.664  98.693  1.00 217.73 ? 504 GLY B N   1 
ATOM   5124  C CA  . GLY B 2 482 ? 179.793 93.163  97.689  1.00 217.73 ? 504 GLY B CA  1 
ATOM   5125  C C   . GLY B 2 482 ? 180.191 94.609  97.920  1.00 217.73 ? 504 GLY B C   1 
ATOM   5126  O O   . GLY B 2 482 ? 179.580 95.340  98.699  1.00 217.73 ? 504 GLY B O   1 
ATOM   5127  N N   . SER B 2 483 ? 181.246 95.022  97.220  1.00 217.59 ? 505 SER B N   1 
ATOM   5128  C CA  . SER B 2 483 ? 181.781 96.374  97.324  1.00 217.59 ? 505 SER B CA  1 
ATOM   5129  C C   . SER B 2 483 ? 181.994 96.927  95.924  1.00 217.59 ? 505 SER B C   1 
ATOM   5130  O O   . SER B 2 483 ? 182.738 96.342  95.130  1.00 217.59 ? 505 SER B O   1 
ATOM   5131  C CB  . SER B 2 483 ? 183.093 96.389  98.114  1.00 217.59 ? 505 SER B CB  1 
ATOM   5132  O OG  . SER B 2 483 ? 184.114 95.694  97.420  1.00 217.59 ? 505 SER B OG  1 
ATOM   5133  N N   . GLU B 2 484 ? 181.343 98.049  95.623  1.00 223.46 ? 506 GLU B N   1 
ATOM   5134  C CA  . GLU B 2 484 ? 181.481 98.716  94.338  1.00 223.46 ? 506 GLU B CA  1 
ATOM   5135  C C   . GLU B 2 484 ? 181.884 100.167 94.559  1.00 223.46 ? 506 GLU B C   1 
ATOM   5136  O O   . GLU B 2 484 ? 181.518 100.784 95.562  1.00 223.46 ? 506 GLU B O   1 
ATOM   5137  C CB  . GLU B 2 484 ? 180.180 98.646  93.524  1.00 223.46 ? 506 GLU B CB  1 
ATOM   5138  C CG  . GLU B 2 484 ? 179.733 97.229  93.197  1.00 223.46 ? 506 GLU B CG  1 
ATOM   5139  C CD  . GLU B 2 484 ? 178.563 97.191  92.233  1.00 223.46 ? 506 GLU B CD  1 
ATOM   5140  O OE1 . GLU B 2 484 ? 178.205 98.255  91.687  1.00 223.46 ? 506 GLU B OE1 1 
ATOM   5141  O OE2 . GLU B 2 484 ? 178.003 96.095  92.021  1.00 223.46 ? 506 GLU B OE2 1 
ATOM   5142  N N   . SER B 2 485 ? 182.641 100.705 93.606  1.00 224.83 ? 507 SER B N   1 
ATOM   5143  C CA  . SER B 2 485 ? 183.179 102.056 93.691  1.00 224.83 ? 507 SER B CA  1 
ATOM   5144  C C   . SER B 2 485 ? 182.596 102.910 92.575  1.00 224.83 ? 507 SER B C   1 
ATOM   5145  O O   . SER B 2 485 ? 182.732 102.572 91.394  1.00 224.83 ? 507 SER B O   1 
ATOM   5146  C CB  . SER B 2 485 ? 184.708 102.044 93.604  1.00 224.83 ? 507 SER B CB  1 
ATOM   5147  O OG  . SER B 2 485 ? 185.233 103.358 93.657  1.00 224.83 ? 507 SER B OG  1 
ATOM   5148  N N   . LEU B 2 486 ? 181.950 104.010 92.950  1.00 224.55 ? 508 LEU B N   1 
ATOM   5149  C CA  . LEU B 2 486 ? 181.365 104.954 92.011  1.00 224.55 ? 508 LEU B CA  1 
ATOM   5150  C C   . LEU B 2 486 ? 181.920 106.350 92.270  1.00 224.55 ? 508 LEU B C   1 
ATOM   5151  O O   . LEU B 2 486 ? 182.518 106.627 93.313  1.00 224.55 ? 508 LEU B O   1 
ATOM   5152  C CB  . LEU B 2 486 ? 179.832 104.969 92.108  1.00 224.55 ? 508 LEU B CB  1 
ATOM   5153  C CG  . LEU B 2 486 ? 179.010 103.909 91.364  1.00 224.55 ? 508 LEU B CG  1 
ATOM   5154  C CD1 . LEU B 2 486 ? 179.175 104.063 89.857  1.00 224.55 ? 508 LEU B CD1 1 
ATOM   5155  C CD2 . LEU B 2 486 ? 179.340 102.489 91.806  1.00 224.55 ? 508 LEU B CD2 1 
ATOM   5156  N N   . LYS B 2 487 ? 181.710 107.236 91.299  1.00 227.58 ? 509 LYS B N   1 
ATOM   5157  C CA  . LYS B 2 487 ? 182.164 108.615 91.376  1.00 227.58 ? 509 LYS B CA  1 
ATOM   5158  C C   . LYS B 2 487 ? 180.991 109.560 91.155  1.00 227.58 ? 509 LYS B C   1 
ATOM   5159  O O   . LYS B 2 487 ? 180.059 109.255 90.403  1.00 227.58 ? 509 LYS B O   1 
ATOM   5160  C CB  . LYS B 2 487 ? 183.262 108.899 90.343  1.00 227.58 ? 509 LYS B CB  1 
ATOM   5161  C CG  . LYS B 2 487 ? 184.452 107.956 90.426  1.00 227.58 ? 509 LYS B CG  1 
ATOM   5162  C CD  . LYS B 2 487 ? 185.115 108.024 91.791  1.00 227.58 ? 509 LYS B CD  1 
ATOM   5163  C CE  . LYS B 2 487 ? 186.253 107.023 91.902  1.00 227.58 ? 509 LYS B CE  1 
ATOM   5164  N NZ  . LYS B 2 487 ? 185.768 105.619 91.798  1.00 227.58 ? 509 LYS B NZ  1 
ATOM   5165  N N   . ALA B 2 488 ? 181.045 110.714 91.816  1.00 233.16 ? 510 ALA B N   1 
ATOM   5166  C CA  . ALA B 2 488 ? 179.985 111.707 91.711  1.00 233.16 ? 510 ALA B CA  1 
ATOM   5167  C C   . ALA B 2 488 ? 180.557 113.073 92.064  1.00 233.16 ? 510 ALA B C   1 
ATOM   5168  O O   . ALA B 2 488 ? 181.694 113.193 92.526  1.00 233.16 ? 510 ALA B O   1 
ATOM   5169  C CB  . ALA B 2 488 ? 178.798 111.357 92.614  1.00 233.16 ? 510 ALA B CB  1 
ATOM   5170  N N   . TYR B 2 489 ? 179.747 114.105 91.837  1.00 234.55 ? 511 TYR B N   1 
ATOM   5171  C CA  . TYR B 2 489 ? 180.128 115.477 92.131  1.00 234.55 ? 511 TYR B CA  1 
ATOM   5172  C C   . TYR B 2 489 ? 178.940 116.215 92.729  1.00 234.55 ? 511 TYR B C   1 
ATOM   5173  O O   . TYR B 2 489 ? 177.784 115.928 92.406  1.00 234.55 ? 511 TYR B O   1 
ATOM   5174  C CB  . TYR B 2 489 ? 180.619 116.211 90.875  1.00 234.55 ? 511 TYR B CB  1 
ATOM   5175  C CG  . TYR B 2 489 ? 182.104 116.077 90.624  1.00 234.55 ? 511 TYR B CG  1 
ATOM   5176  C CD1 . TYR B 2 489 ? 182.999 117.017 91.117  1.00 234.55 ? 511 TYR B CD1 1 
ATOM   5177  C CD2 . TYR B 2 489 ? 182.610 115.012 89.891  1.00 234.55 ? 511 TYR B CD2 1 
ATOM   5178  C CE1 . TYR B 2 489 ? 184.357 116.900 90.889  1.00 234.55 ? 511 TYR B CE1 1 
ATOM   5179  C CE2 . TYR B 2 489 ? 183.967 114.886 89.657  1.00 234.55 ? 511 TYR B CE2 1 
ATOM   5180  C CZ  . TYR B 2 489 ? 184.835 115.833 90.158  1.00 234.55 ? 511 TYR B CZ  1 
ATOM   5181  O OH  . TYR B 2 489 ? 186.186 115.712 89.928  1.00 234.55 ? 511 TYR B OH  1 
ATOM   5182  N N   . LEU B 2 490 ? 179.236 117.171 93.609  1.00 223.61 ? 512 LEU B N   1 
ATOM   5183  C CA  . LEU B 2 490 ? 178.199 117.980 94.238  1.00 223.61 ? 512 LEU B CA  1 
ATOM   5184  C C   . LEU B 2 490 ? 177.889 119.230 93.421  1.00 223.61 ? 512 LEU B C   1 
ATOM   5185  O O   . LEU B 2 490 ? 176.725 119.499 93.108  1.00 223.61 ? 512 LEU B O   1 
ATOM   5186  C CB  . LEU B 2 490 ? 178.623 118.365 95.660  1.00 223.61 ? 512 LEU B CB  1 
ATOM   5187  C CG  . LEU B 2 490 ? 177.726 119.332 96.441  1.00 223.61 ? 512 LEU B CG  1 
ATOM   5188  C CD1 . LEU B 2 490 ? 176.256 118.939 96.337  1.00 223.61 ? 512 LEU B CD1 1 
ATOM   5189  C CD2 . LEU B 2 490 ? 178.159 119.414 97.898  1.00 223.61 ? 512 LEU B CD2 1 
ATOM   5190  N N   . LYS B 2 491 ? 178.918 119.999 93.069  1.00 230.74 ? 513 LYS B N   1 
ATOM   5191  C CA  . LYS B 2 491 ? 178.753 121.223 92.284  1.00 230.74 ? 513 LYS B CA  1 
ATOM   5192  C C   . LYS B 2 491 ? 179.952 121.333 91.348  1.00 230.74 ? 513 LYS B C   1 
ATOM   5193  O O   . LYS B 2 491 ? 181.035 121.756 91.764  1.00 230.74 ? 513 LYS B O   1 
ATOM   5194  C CB  . LYS B 2 491 ? 178.633 122.447 93.184  1.00 230.74 ? 513 LYS B CB  1 
ATOM   5195  C CG  . LYS B 2 491 ? 178.449 123.755 92.431  1.00 230.74 ? 513 LYS B CG  1 
ATOM   5196  C CD  . LYS B 2 491 ? 178.339 124.930 93.388  1.00 230.74 ? 513 LYS B CD  1 
ATOM   5197  C CE  . LYS B 2 491 ? 178.128 126.236 92.639  1.00 230.74 ? 513 LYS B CE  1 
ATOM   5198  N NZ  . LYS B 2 491 ? 177.999 127.391 93.569  1.00 230.74 ? 513 LYS B NZ  1 
ATOM   5199  N N   . GLN B 2 492 ? 179.754 120.952 90.089  1.00 247.70 ? 514 GLN B N   1 
ATOM   5200  C CA  . GLN B 2 492 ? 180.833 120.983 89.117  1.00 247.70 ? 514 GLN B CA  1 
ATOM   5201  C C   . GLN B 2 492 ? 181.191 122.422 88.754  1.00 247.70 ? 514 GLN B C   1 
ATOM   5202  O O   . GLN B 2 492 ? 180.395 123.352 88.912  1.00 247.70 ? 514 GLN B O   1 
ATOM   5203  C CB  . GLN B 2 492 ? 180.444 120.204 87.860  1.00 247.70 ? 514 GLN B CB  1 
ATOM   5204  C CG  . GLN B 2 492 ? 180.062 118.756 88.125  1.00 247.70 ? 514 GLN B CG  1 
ATOM   5205  C CD  . GLN B 2 492 ? 179.658 118.018 86.865  1.00 247.70 ? 514 GLN B CD  1 
ATOM   5206  O OE1 . GLN B 2 492 ? 180.486 117.386 86.208  1.00 247.70 ? 514 GLN B OE1 1 
ATOM   5207  N NE2 . GLN B 2 492 ? 178.377 118.092 86.521  1.00 247.70 ? 514 GLN B NE2 1 
ATOM   5208  N N   . ALA B 2 493 ? 182.416 122.596 88.264  1.00 253.86 ? 515 ALA B N   1 
ATOM   5209  C CA  . ALA B 2 493 ? 182.910 123.908 87.874  1.00 253.86 ? 515 ALA B CA  1 
ATOM   5210  C C   . ALA B 2 493 ? 183.927 123.738 86.755  1.00 253.86 ? 515 ALA B C   1 
ATOM   5211  O O   . ALA B 2 493 ? 184.366 122.626 86.448  1.00 253.86 ? 515 ALA B O   1 
ATOM   5212  C CB  . ALA B 2 493 ? 183.523 124.654 89.064  1.00 253.86 ? 515 ALA B CB  1 
ATOM   5213  N N   . ALA B 2 494 ? 184.295 124.859 86.144  1.00 253.51 ? 516 ALA B N   1 
ATOM   5214  C CA  . ALA B 2 494 ? 185.275 124.828 85.070  1.00 253.51 ? 516 ALA B CA  1 
ATOM   5215  C C   . ALA B 2 494 ? 186.644 124.436 85.621  1.00 253.51 ? 516 ALA B C   1 
ATOM   5216  O O   . ALA B 2 494 ? 186.982 124.789 86.756  1.00 253.51 ? 516 ALA B O   1 
ATOM   5217  C CB  . ALA B 2 494 ? 185.358 126.188 84.379  1.00 253.51 ? 516 ALA B CB  1 
ATOM   5218  N N   . PRO B 2 495 ? 187.447 123.700 84.853  1.00 252.99 ? 517 PRO B N   1 
ATOM   5219  C CA  . PRO B 2 495 ? 188.776 123.310 85.336  1.00 252.99 ? 517 PRO B CA  1 
ATOM   5220  C C   . PRO B 2 495 ? 189.674 124.521 85.540  1.00 252.99 ? 517 PRO B C   1 
ATOM   5221  O O   . PRO B 2 495 ? 189.484 125.583 84.943  1.00 252.99 ? 517 PRO B O   1 
ATOM   5222  C CB  . PRO B 2 495 ? 189.311 122.401 84.221  1.00 252.99 ? 517 PRO B CB  1 
ATOM   5223  C CG  . PRO B 2 495 ? 188.097 121.962 83.460  1.00 252.99 ? 517 PRO B CG  1 
ATOM   5224  C CD  . PRO B 2 495 ? 187.139 123.109 83.540  1.00 252.99 ? 517 PRO B CD  1 
ATOM   5225  N N   . ALA B 2 496 ? 190.672 124.346 86.409  1.00 243.97 ? 518 ALA B N   1 
ATOM   5226  C CA  . ALA B 2 496 ? 191.583 125.444 86.712  1.00 243.97 ? 518 ALA B CA  1 
ATOM   5227  C C   . ALA B 2 496 ? 192.548 125.700 85.561  1.00 243.97 ? 518 ALA B C   1 
ATOM   5228  O O   . ALA B 2 496 ? 192.810 126.856 85.210  1.00 243.97 ? 518 ALA B O   1 
ATOM   5229  C CB  . ALA B 2 496 ? 192.349 125.152 88.002  1.00 243.97 ? 518 ALA B CB  1 
ATOM   5230  N N   . ARG B 2 497 ? 193.086 124.639 84.963  1.00 241.91 ? 519 ARG B N   1 
ATOM   5231  C CA  . ARG B 2 497 ? 194.044 124.770 83.877  1.00 241.91 ? 519 ARG B CA  1 
ATOM   5232  C C   . ARG B 2 497 ? 193.709 123.767 82.782  1.00 241.91 ? 519 ARG B C   1 
ATOM   5233  O O   . ARG B 2 497 ? 193.207 122.673 83.053  1.00 241.91 ? 519 ARG B O   1 
ATOM   5234  C CB  . ARG B 2 497 ? 195.483 124.553 84.366  1.00 241.91 ? 519 ARG B CB  1 
ATOM   5235  C CG  . ARG B 2 497 ? 196.551 125.023 83.391  1.00 241.91 ? 519 ARG B CG  1 
ATOM   5236  C CD  . ARG B 2 497 ? 197.936 124.577 83.832  1.00 241.91 ? 519 ARG B CD  1 
ATOM   5237  N NE  . ARG B 2 497 ? 198.025 123.126 83.960  1.00 241.91 ? 519 ARG B NE  1 
ATOM   5238  C CZ  . ARG B 2 497 ? 198.243 122.297 82.944  1.00 241.91 ? 519 ARG B CZ  1 
ATOM   5239  N NH1 . ARG B 2 497 ? 198.394 122.773 81.716  1.00 241.91 ? 519 ARG B NH1 1 
ATOM   5240  N NH2 . ARG B 2 497 ? 198.308 120.989 83.156  1.00 241.91 ? 519 ARG B NH2 1 
ATOM   5241  N N   . GLY B 2 498 ? 193.994 124.153 81.543  1.00 246.87 ? 520 GLY B N   1 
ATOM   5242  C CA  . GLY B 2 498 ? 193.762 123.291 80.409  1.00 246.87 ? 520 GLY B CA  1 
ATOM   5243  C C   . GLY B 2 498 ? 194.816 122.214 80.291  1.00 246.87 ? 520 GLY B C   1 
ATOM   5244  O O   . GLY B 2 498 ? 195.891 122.266 80.907  1.00 246.87 ? 520 GLY B O   1 
ATOM   5245  N N   . PRO B 2 499 ? 194.515 121.203 79.479  1.00 260.80 ? 521 PRO B N   1 
ATOM   5246  C CA  . PRO B 2 499 ? 195.454 120.090 79.317  1.00 260.80 ? 521 PRO B CA  1 
ATOM   5247  C C   . PRO B 2 499 ? 196.669 120.492 78.496  1.00 260.80 ? 521 PRO B C   1 
ATOM   5248  O O   . PRO B 2 499 ? 196.598 121.343 77.606  1.00 260.80 ? 521 PRO B O   1 
ATOM   5249  C CB  . PRO B 2 499 ? 194.620 119.028 78.592  1.00 260.80 ? 521 PRO B CB  1 
ATOM   5250  C CG  . PRO B 2 499 ? 193.600 119.814 77.839  1.00 260.80 ? 521 PRO B CG  1 
ATOM   5251  C CD  . PRO B 2 499 ? 193.283 121.013 78.693  1.00 260.80 ? 521 PRO B CD  1 
ATOM   5252  N N   . THR B 2 500 ? 197.798 119.862 78.812  1.00 266.63 ? 522 THR B N   1 
ATOM   5253  C CA  . THR B 2 500 ? 199.030 120.102 78.072  1.00 266.63 ? 522 THR B CA  1 
ATOM   5254  C C   . THR B 2 500 ? 198.975 119.367 76.738  1.00 266.63 ? 522 THR B C   1 
ATOM   5255  O O   . THR B 2 500 ? 198.870 118.137 76.702  1.00 266.63 ? 522 THR B O   1 
ATOM   5256  C CB  . THR B 2 500 ? 200.238 119.645 78.886  1.00 266.63 ? 522 THR B CB  1 
ATOM   5257  O OG1 . THR B 2 500 ? 200.143 118.237 79.136  1.00 266.63 ? 522 THR B OG1 1 
ATOM   5258  C CG2 . THR B 2 500 ? 200.294 120.386 80.214  1.00 266.63 ? 522 THR B CG2 1 
ATOM   5259  N N   . VAL B 2 501 ? 199.048 120.119 75.643  1.00 269.40 ? 523 VAL B N   1 
ATOM   5260  C CA  . VAL B 2 501 ? 198.924 119.571 74.297  1.00 269.40 ? 523 VAL B CA  1 
ATOM   5261  C C   . VAL B 2 501 ? 200.315 119.423 73.697  1.00 269.40 ? 523 VAL B C   1 
ATOM   5262  O O   . VAL B 2 501 ? 201.109 120.372 73.705  1.00 269.40 ? 523 VAL B O   1 
ATOM   5263  C CB  . VAL B 2 501 ? 198.035 120.463 73.415  1.00 269.40 ? 523 VAL B CB  1 
ATOM   5264  C CG1 . VAL B 2 501 ? 198.010 119.943 71.988  1.00 269.40 ? 523 VAL B CG1 1 
ATOM   5265  C CG2 . VAL B 2 501 ? 196.630 120.535 73.987  1.00 269.40 ? 523 VAL B CG2 1 
ATOM   5266  N N   . ARG B 2 502 ? 200.608 118.233 73.178  1.00 272.39 ? 524 ARG B N   1 
ATOM   5267  C CA  . ARG B 2 502 ? 201.884 117.945 72.542  1.00 272.39 ? 524 ARG B CA  1 
ATOM   5268  C C   . ARG B 2 502 ? 201.638 117.322 71.175  1.00 272.39 ? 524 ARG B C   1 
ATOM   5269  O O   . ARG B 2 502 ? 200.551 116.817 70.884  1.00 272.39 ? 524 ARG B O   1 
ATOM   5270  C CB  . ARG B 2 502 ? 202.744 117.009 73.402  1.00 272.39 ? 524 ARG B CB  1 
ATOM   5271  C CG  . ARG B 2 502 ? 202.011 115.771 73.889  1.00 272.39 ? 524 ARG B CG  1 
ATOM   5272  C CD  . ARG B 2 502 ? 202.656 115.204 75.143  1.00 272.39 ? 524 ARG B CD  1 
ATOM   5273  N NE  . ARG B 2 502 ? 201.844 114.153 75.749  1.00 272.39 ? 524 ARG B NE  1 
ATOM   5274  C CZ  . ARG B 2 502 ? 200.818 114.379 76.564  1.00 272.39 ? 524 ARG B CZ  1 
ATOM   5275  N NH1 . ARG B 2 502 ? 200.474 115.621 76.873  1.00 272.39 ? 524 ARG B NH1 1 
ATOM   5276  N NH2 . ARG B 2 502 ? 200.135 113.361 77.069  1.00 272.39 ? 524 ARG B NH2 1 
ATOM   5277  N N   . THR B 2 503 ? 202.667 117.365 70.334  1.00 268.97 ? 525 THR B N   1 
ATOM   5278  C CA  . THR B 2 503 ? 202.609 116.824 68.982  1.00 268.97 ? 525 THR B CA  1 
ATOM   5279  C C   . THR B 2 503 ? 203.458 115.562 68.918  1.00 268.97 ? 525 THR B C   1 
ATOM   5280  O O   . THR B 2 503 ? 204.663 115.605 69.190  1.00 268.97 ? 525 THR B O   1 
ATOM   5281  C CB  . THR B 2 503 ? 203.095 117.849 67.957  1.00 268.97 ? 525 THR B CB  1 
ATOM   5282  O OG1 . THR B 2 503 ? 202.438 119.103 68.184  1.00 268.97 ? 525 THR B OG1 1 
ATOM   5283  C CG2 . THR B 2 503 ? 202.792 117.373 66.544  1.00 268.97 ? 525 THR B CG2 1 
ATOM   5284  N N   . LYS B 2 504 ? 202.829 114.441 68.559  1.00 269.43 ? 526 LYS B N   1 
ATOM   5285  C CA  . LYS B 2 504 ? 203.553 113.180 68.459  1.00 269.43 ? 526 LYS B CA  1 
ATOM   5286  C C   . LYS B 2 504 ? 204.273 113.036 67.125  1.00 269.43 ? 526 LYS B C   1 
ATOM   5287  O O   . LYS B 2 504 ? 205.360 112.450 67.074  1.00 269.43 ? 526 LYS B O   1 
ATOM   5288  C CB  . LYS B 2 504 ? 202.595 112.005 68.665  1.00 269.43 ? 526 LYS B CB  1 
ATOM   5289  C CG  . LYS B 2 504 ? 201.978 111.945 70.052  1.00 269.43 ? 526 LYS B CG  1 
ATOM   5290  C CD  . LYS B 2 504 ? 203.046 111.786 71.122  1.00 269.43 ? 526 LYS B CD  1 
ATOM   5291  C CE  . LYS B 2 504 ? 202.606 112.408 72.437  1.00 269.43 ? 526 LYS B CE  1 
ATOM   5292  N NZ  . LYS B 2 504 ? 201.728 111.492 73.218  1.00 269.43 ? 526 LYS B NZ  1 
ATOM   5293  N N   . LYS B 2 505 ? 203.694 113.557 66.046  1.00 270.05 ? 527 LYS B N   1 
ATOM   5294  C CA  . LYS B 2 505 ? 204.311 113.467 64.731  1.00 270.05 ? 527 LYS B CA  1 
ATOM   5295  C C   . LYS B 2 505 ? 203.776 114.591 63.856  1.00 270.05 ? 527 LYS B C   1 
ATOM   5296  O O   . LYS B 2 505 ? 202.671 115.093 64.075  1.00 270.05 ? 527 LYS B O   1 
ATOM   5297  C CB  . LYS B 2 505 ? 204.047 112.103 64.078  1.00 270.05 ? 527 LYS B CB  1 
ATOM   5298  C CG  . LYS B 2 505 ? 202.577 111.799 63.815  1.00 270.05 ? 527 LYS B CG  1 
ATOM   5299  C CD  . LYS B 2 505 ? 202.199 112.057 62.363  1.00 270.05 ? 527 LYS B CD  1 
ATOM   5300  C CE  . LYS B 2 505 ? 200.755 111.671 62.090  1.00 270.05 ? 527 LYS B CE  1 
ATOM   5301  N NZ  . LYS B 2 505 ? 200.367 111.938 60.677  1.00 270.05 ? 527 LYS B NZ  1 
ATOM   5302  N N   . VAL B 2 506 ? 204.577 114.979 62.867  1.00 268.54 ? 528 VAL B N   1 
ATOM   5303  C CA  . VAL B 2 506 ? 204.204 116.003 61.901  1.00 268.54 ? 528 VAL B CA  1 
ATOM   5304  C C   . VAL B 2 506 ? 204.448 115.455 60.501  1.00 268.54 ? 528 VAL B C   1 
ATOM   5305  O O   . VAL B 2 506 ? 205.415 114.720 60.271  1.00 268.54 ? 528 VAL B O   1 
ATOM   5306  C CB  . VAL B 2 506 ? 204.984 117.318 62.133  1.00 268.54 ? 528 VAL B CB  1 
ATOM   5307  C CG1 . VAL B 2 506 ? 206.483 117.102 61.962  1.00 268.54 ? 528 VAL B CG1 1 
ATOM   5308  C CG2 . VAL B 2 506 ? 204.479 118.418 61.208  1.00 268.54 ? 528 VAL B CG2 1 
ATOM   5309  N N   . GLY B 2 507 ? 203.556 115.793 59.573  1.00 276.03 ? 529 GLY B N   1 
ATOM   5310  C CA  . GLY B 2 507 ? 203.666 115.305 58.212  1.00 276.03 ? 529 GLY B CA  1 
ATOM   5311  C C   . GLY B 2 507 ? 203.572 116.398 57.169  1.00 276.03 ? 529 GLY B C   1 
ATOM   5312  O O   . GLY B 2 507 ? 203.595 117.588 57.501  1.00 276.03 ? 529 GLY B O   1 
ATOM   5313  N N   . LYS B 2 508 ? 203.465 116.004 55.898  1.00 282.94 ? 530 LYS B N   1 
ATOM   5314  C CA  . LYS B 2 508 ? 203.369 116.990 54.826  1.00 282.94 ? 530 LYS B CA  1 
ATOM   5315  C C   . LYS B 2 508 ? 202.016 117.692 54.839  1.00 282.94 ? 530 LYS B C   1 
ATOM   5316  O O   . LYS B 2 508 ? 201.947 118.919 54.711  1.00 282.94 ? 530 LYS B O   1 
ATOM   5317  C CB  . LYS B 2 508 ? 203.613 116.319 53.474  1.00 282.94 ? 530 LYS B CB  1 
ATOM   5318  C CG  . LYS B 2 508 ? 204.928 115.549 53.359  1.00 282.94 ? 530 LYS B CG  1 
ATOM   5319  C CD  . LYS B 2 508 ? 206.147 116.434 53.605  1.00 282.94 ? 530 LYS B CD  1 
ATOM   5320  C CE  . LYS B 2 508 ? 206.768 116.179 54.973  1.00 282.94 ? 530 LYS B CE  1 
ATOM   5321  N NZ  . LYS B 2 508 ? 207.918 117.086 55.241  1.00 282.94 ? 530 LYS B NZ  1 
ATOM   5322  N N   . ASN B 2 509 ? 200.930 116.930 54.994  1.00 284.45 ? 531 ASN B N   1 
ATOM   5323  C CA  . ASN B 2 509 ? 199.596 117.516 55.020  1.00 284.45 ? 531 ASN B CA  1 
ATOM   5324  C C   . ASN B 2 509 ? 198.729 116.959 56.143  1.00 284.45 ? 531 ASN B C   1 
ATOM   5325  O O   . ASN B 2 509 ? 197.544 117.310 56.218  1.00 284.45 ? 531 ASN B O   1 
ATOM   5326  C CB  . ASN B 2 509 ? 198.893 117.312 53.671  1.00 284.45 ? 531 ASN B CB  1 
ATOM   5327  C CG  . ASN B 2 509 ? 198.679 115.848 53.339  1.00 284.45 ? 531 ASN B CG  1 
ATOM   5328  O OD1 . ASN B 2 509 ? 197.748 115.215 53.836  1.00 284.45 ? 531 ASN B OD1 1 
ATOM   5329  N ND2 . ASN B 2 509 ? 199.545 115.301 52.493  1.00 284.45 ? 531 ASN B ND2 1 
ATOM   5330  N N   . GLU B 2 510 ? 199.271 116.109 57.011  1.00 283.02 ? 532 GLU B N   1 
ATOM   5331  C CA  . GLU B 2 510 ? 198.521 115.554 58.128  1.00 283.02 ? 532 GLU B CA  1 
ATOM   5332  C C   . GLU B 2 510 ? 199.354 115.673 59.395  1.00 283.02 ? 532 GLU B C   1 
ATOM   5333  O O   . GLU B 2 510 ? 200.586 115.717 59.352  1.00 283.02 ? 532 GLU B O   1 
ATOM   5334  C CB  . GLU B 2 510 ? 198.135 114.088 57.883  1.00 283.02 ? 532 GLU B CB  1 
ATOM   5335  C CG  . GLU B 2 510 ? 197.085 113.889 56.801  1.00 283.02 ? 532 GLU B CG  1 
ATOM   5336  C CD  . GLU B 2 510 ? 195.745 114.495 57.169  1.00 283.02 ? 532 GLU B CD  1 
ATOM   5337  O OE1 . GLU B 2 510 ? 195.364 115.513 56.556  1.00 283.02 ? 532 GLU B OE1 1 
ATOM   5338  O OE2 . GLU B 2 510 ? 195.073 113.953 58.072  1.00 283.02 ? 532 GLU B OE2 1 
ATOM   5339  N N   . ALA B 2 511 ? 198.663 115.723 60.533  1.00 282.51 ? 533 ALA B N   1 
ATOM   5340  C CA  . ALA B 2 511 ? 199.328 115.847 61.824  1.00 282.51 ? 533 ALA B CA  1 
ATOM   5341  C C   . ALA B 2 511 ? 198.366 115.416 62.919  1.00 282.51 ? 533 ALA B C   1 
ATOM   5342  O O   . ALA B 2 511 ? 197.234 115.907 62.980  1.00 282.51 ? 533 ALA B O   1 
ATOM   5343  C CB  . ALA B 2 511 ? 199.805 117.284 62.067  1.00 282.51 ? 533 ALA B CB  1 
ATOM   5344  N N   . VAL B 2 512 ? 198.814 114.506 63.774  1.00 282.53 ? 534 VAL B N   1 
ATOM   5345  C CA  . VAL B 2 512 ? 198.026 114.049 64.912  1.00 282.53 ? 534 VAL B CA  1 
ATOM   5346  C C   . VAL B 2 512 ? 198.308 114.964 66.096  1.00 282.53 ? 534 VAL B C   1 
ATOM   5347  O O   . VAL B 2 512 ? 199.372 115.584 66.192  1.00 282.53 ? 534 VAL B O   1 
ATOM   5348  C CB  . VAL B 2 512 ? 198.333 112.571 65.242  1.00 282.53 ? 534 VAL B CB  1 
ATOM   5349  C CG1 . VAL B 2 512 ? 199.660 112.444 65.978  1.00 282.53 ? 534 VAL B CG1 1 
ATOM   5350  C CG2 . VAL B 2 512 ? 197.200 111.952 66.051  1.00 282.53 ? 534 VAL B CG2 1 
ATOM   5351  N N   . LEU B 2 513 ? 197.337 115.066 66.999  1.00 282.07 ? 535 LEU B N   1 
ATOM   5352  C CA  . LEU B 2 513 ? 197.447 115.908 68.182  1.00 282.07 ? 535 LEU B CA  1 
ATOM   5353  C C   . LEU B 2 513 ? 197.171 115.072 69.423  1.00 282.07 ? 535 LEU B C   1 
ATOM   5354  O O   . LEU B 2 513 ? 196.172 114.348 69.478  1.00 282.07 ? 535 LEU B O   1 
ATOM   5355  C CB  . LEU B 2 513 ? 196.477 117.090 68.109  1.00 282.07 ? 535 LEU B CB  1 
ATOM   5356  C CG  . LEU B 2 513 ? 196.886 118.336 68.897  1.00 282.07 ? 535 LEU B CG  1 
ATOM   5357  C CD1 . LEU B 2 513 ? 198.197 118.898 68.368  1.00 282.07 ? 535 LEU B CD1 1 
ATOM   5358  C CD2 . LEU B 2 513 ? 195.789 119.387 68.849  1.00 282.07 ? 535 LEU B CD2 1 
ATOM   5359  N N   . ALA B 2 514 ? 198.054 115.176 70.411  1.00 280.07 ? 536 ALA B N   1 
ATOM   5360  C CA  . ALA B 2 514 ? 197.928 114.443 71.659  1.00 280.07 ? 536 ALA B CA  1 
ATOM   5361  C C   . ALA B 2 514 ? 197.810 115.416 72.825  1.00 280.07 ? 536 ALA B C   1 
ATOM   5362  O O   . ALA B 2 514 ? 198.101 116.609 72.700  1.00 280.07 ? 536 ALA B O   1 
ATOM   5363  C CB  . ALA B 2 514 ? 199.120 113.504 71.880  1.00 280.07 ? 536 ALA B CB  1 
ATOM   5364  N N   . TRP B 2 515 ? 197.378 114.887 73.966  1.00 277.83 ? 537 TRP B N   1 
ATOM   5365  C CA  . TRP B 2 515 ? 197.209 115.691 75.167  1.00 277.83 ? 537 TRP B CA  1 
ATOM   5366  C C   . TRP B 2 515 ? 197.233 114.771 76.378  1.00 277.83 ? 537 TRP B C   1 
ATOM   5367  O O   . TRP B 2 515 ? 197.070 113.554 76.259  1.00 277.83 ? 537 TRP B O   1 
ATOM   5368  C CB  . TRP B 2 515 ? 195.907 116.500 75.126  1.00 277.83 ? 537 TRP B CB  1 
ATOM   5369  C CG  . TRP B 2 515 ? 194.697 115.679 74.797  1.00 277.83 ? 537 TRP B CG  1 
ATOM   5370  C CD1 . TRP B 2 515 ? 193.930 114.965 75.671  1.00 277.83 ? 537 TRP B CD1 1 
ATOM   5371  C CD2 . TRP B 2 515 ? 194.112 115.489 73.503  1.00 277.83 ? 537 TRP B CD2 1 
ATOM   5372  N NE1 . TRP B 2 515 ? 192.905 114.341 75.001  1.00 277.83 ? 537 TRP B NE1 1 
ATOM   5373  C CE2 . TRP B 2 515 ? 192.994 114.647 73.669  1.00 277.83 ? 537 TRP B CE2 1 
ATOM   5374  C CE3 . TRP B 2 515 ? 194.425 115.949 72.220  1.00 277.83 ? 537 TRP B CE3 1 
ATOM   5375  C CZ2 . TRP B 2 515 ? 192.189 114.256 72.601  1.00 277.83 ? 537 TRP B CZ2 1 
ATOM   5376  C CZ3 . TRP B 2 515 ? 193.625 115.558 71.161  1.00 277.83 ? 537 TRP B CZ3 1 
ATOM   5377  C CH2 . TRP B 2 515 ? 192.520 114.720 71.358  1.00 277.83 ? 537 TRP B CH2 1 
ATOM   5378  N N   . ASP B 2 516 ? 197.440 115.371 77.544  1.00 272.41 ? 538 ASP B N   1 
ATOM   5379  C CA  . ASP B 2 516 ? 197.488 114.641 78.800  1.00 272.41 ? 538 ASP B CA  1 
ATOM   5380  C C   . ASP B 2 516 ? 196.176 114.827 79.552  1.00 272.41 ? 538 ASP B C   1 
ATOM   5381  O O   . ASP B 2 516 ? 195.476 115.828 79.380  1.00 272.41 ? 538 ASP B O   1 
ATOM   5382  C CB  . ASP B 2 516 ? 198.667 115.111 79.659  1.00 272.41 ? 538 ASP B CB  1 
ATOM   5383  C CG  . ASP B 2 516 ? 198.893 114.238 80.882  1.00 272.41 ? 538 ASP B CG  1 
ATOM   5384  O OD1 . ASP B 2 516 ? 198.000 114.168 81.752  1.00 272.41 ? 538 ASP B OD1 1 
ATOM   5385  O OD2 . ASP B 2 516 ? 199.973 113.617 80.973  1.00 272.41 ? 538 ASP B OD2 1 
ATOM   5386  N N   . GLN B 2 517 ? 195.846 113.847 80.388  1.00 262.96 ? 539 GLN B N   1 
ATOM   5387  C CA  . GLN B 2 517 ? 194.593 113.885 81.127  1.00 262.96 ? 539 GLN B CA  1 
ATOM   5388  C C   . GLN B 2 517 ? 194.622 114.974 82.193  1.00 262.96 ? 539 GLN B C   1 
ATOM   5389  O O   . GLN B 2 517 ? 195.676 115.334 82.724  1.00 262.96 ? 539 GLN B O   1 
ATOM   5390  C CB  . GLN B 2 517 ? 194.306 112.519 81.760  1.00 262.96 ? 539 GLN B CB  1 
ATOM   5391  C CG  . GLN B 2 517 ? 195.354 112.021 82.758  1.00 262.96 ? 539 GLN B CG  1 
ATOM   5392  C CD  . GLN B 2 517 ? 195.238 112.666 84.128  1.00 262.96 ? 539 GLN B CD  1 
ATOM   5393  O OE1 . GLN B 2 517 ? 194.211 112.552 84.796  1.00 262.96 ? 539 GLN B OE1 1 
ATOM   5394  N NE2 . GLN B 2 517 ? 196.293 113.353 84.549  1.00 262.96 ? 539 GLN B NE2 1 
ATOM   5395  N N   . ILE B 2 518 ? 193.446 115.503 82.501  1.00 257.65 ? 540 ILE B N   1 
ATOM   5396  C CA  . ILE B 2 518 ? 193.321 116.498 83.566  1.00 257.65 ? 540 ILE B CA  1 
ATOM   5397  C C   . ILE B 2 518 ? 193.261 115.773 84.908  1.00 257.65 ? 540 ILE B C   1 
ATOM   5398  O O   . ILE B 2 518 ? 192.450 114.845 85.064  1.00 257.65 ? 540 ILE B O   1 
ATOM   5399  C CB  . ILE B 2 518 ? 192.084 117.363 83.351  1.00 257.65 ? 540 ILE B CB  1 
ATOM   5400  C CG1 . ILE B 2 518 ? 192.215 118.162 82.053  1.00 257.65 ? 540 ILE B CG1 1 
ATOM   5401  C CG2 . ILE B 2 518 ? 191.879 118.302 84.525  1.00 257.65 ? 540 ILE B CG2 1 
ATOM   5402  C CD1 . ILE B 2 518 ? 191.141 119.211 81.873  1.00 257.65 ? 540 ILE B CD1 1 
ATOM   5403  N N   . PRO B 2 519 ? 194.093 116.146 85.880  1.00 256.27 ? 541 PRO B N   1 
ATOM   5404  C CA  . PRO B 2 519 ? 194.082 115.451 87.172  1.00 256.27 ? 541 PRO B CA  1 
ATOM   5405  C C   . PRO B 2 519 ? 192.739 115.583 87.874  1.00 256.27 ? 541 PRO B C   1 
ATOM   5406  O O   . PRO B 2 519 ? 191.930 116.464 87.575  1.00 256.27 ? 541 PRO B O   1 
ATOM   5407  C CB  . PRO B 2 519 ? 195.196 116.149 87.963  1.00 256.27 ? 541 PRO B CB  1 
ATOM   5408  C CG  . PRO B 2 519 ? 196.071 116.773 86.923  1.00 256.27 ? 541 PRO B CG  1 
ATOM   5409  C CD  . PRO B 2 519 ? 195.151 117.167 85.808  1.00 256.27 ? 541 PRO B CD  1 
ATOM   5410  N N   . VAL B 2 520 ? 192.511 114.679 88.831  1.00 254.56 ? 542 VAL B N   1 
ATOM   5411  C CA  . VAL B 2 520 ? 191.235 114.647 89.542  1.00 254.56 ? 542 VAL B CA  1 
ATOM   5412  C C   . VAL B 2 520 ? 191.027 115.934 90.329  1.00 254.56 ? 542 VAL B C   1 
ATOM   5413  O O   . VAL B 2 520 ? 189.909 116.460 90.403  1.00 254.56 ? 542 VAL B O   1 
ATOM   5414  C CB  . VAL B 2 520 ? 191.164 113.408 90.453  1.00 254.56 ? 542 VAL B CB  1 
ATOM   5415  C CG1 . VAL B 2 520 ? 189.737 113.178 90.920  1.00 254.56 ? 542 VAL B CG1 1 
ATOM   5416  C CG2 . VAL B 2 520 ? 191.696 112.184 89.725  1.00 254.56 ? 542 VAL B CG2 1 
ATOM   5417  N N   . ASP B 2 521 ? 192.095 116.463 90.929  1.00 251.70 ? 543 ASP B N   1 
ATOM   5418  C CA  . ASP B 2 521 ? 192.001 117.729 91.644  1.00 251.70 ? 543 ASP B CA  1 
ATOM   5419  C C   . ASP B 2 521 ? 191.881 118.924 90.707  1.00 251.70 ? 543 ASP B C   1 
ATOM   5420  O O   . ASP B 2 521 ? 191.698 120.048 91.185  1.00 251.70 ? 543 ASP B O   1 
ATOM   5421  C CB  . ASP B 2 521 ? 193.214 117.907 92.558  1.00 251.70 ? 543 ASP B CB  1 
ATOM   5422  C CG  . ASP B 2 521 ? 193.201 116.953 93.736  1.00 251.70 ? 543 ASP B CG  1 
ATOM   5423  O OD1 . ASP B 2 521 ? 192.104 116.672 94.264  1.00 251.70 ? 543 ASP B OD1 1 
ATOM   5424  O OD2 . ASP B 2 521 ? 194.287 116.484 94.136  1.00 251.70 ? 543 ASP B OD2 1 
ATOM   5425  N N   . ASP B 2 522 ? 191.977 118.708 89.394  1.00 250.82 ? 544 ASP B N   1 
ATOM   5426  C CA  . ASP B 2 522 ? 191.878 119.779 88.415  1.00 250.82 ? 544 ASP B CA  1 
ATOM   5427  C C   . ASP B 2 522 ? 190.655 119.659 87.516  1.00 250.82 ? 544 ASP B C   1 
ATOM   5428  O O   . ASP B 2 522 ? 190.298 120.636 86.852  1.00 250.82 ? 544 ASP B O   1 
ATOM   5429  C CB  . ASP B 2 522 ? 193.145 119.812 87.544  1.00 250.82 ? 544 ASP B CB  1 
ATOM   5430  C CG  . ASP B 2 522 ? 193.345 121.141 86.837  1.00 250.82 ? 544 ASP B CG  1 
ATOM   5431  O OD1 . ASP B 2 522 ? 192.517 122.057 87.019  1.00 250.82 ? 544 ASP B OD1 1 
ATOM   5432  O OD2 . ASP B 2 522 ? 194.341 121.270 86.094  1.00 250.82 ? 544 ASP B OD2 1 
ATOM   5433  N N   . GLN B 2 523 ? 190.002 118.495 87.485  1.00 251.59 ? 545 GLN B N   1 
ATOM   5434  C CA  . GLN B 2 523 ? 188.825 118.327 86.638  1.00 251.59 ? 545 GLN B CA  1 
ATOM   5435  C C   . GLN B 2 523 ? 187.666 119.187 87.127  1.00 251.59 ? 545 GLN B C   1 
ATOM   5436  O O   . GLN B 2 523 ? 187.015 119.877 86.333  1.00 251.59 ? 545 GLN B O   1 
ATOM   5437  C CB  . GLN B 2 523 ? 188.421 116.853 86.590  1.00 251.59 ? 545 GLN B CB  1 
ATOM   5438  C CG  . GLN B 2 523 ? 189.340 115.980 85.750  1.00 251.59 ? 545 GLN B CG  1 
ATOM   5439  C CD  . GLN B 2 523 ? 188.999 114.506 85.852  1.00 251.59 ? 545 GLN B CD  1 
ATOM   5440  O OE1 . GLN B 2 523 ? 188.176 114.103 86.673  1.00 251.59 ? 545 GLN B OE1 1 
ATOM   5441  N NE2 . GLN B 2 523 ? 189.633 113.693 85.015  1.00 251.59 ? 545 GLN B NE2 1 
ATOM   5442  N N   . ASN B 2 524 ? 187.393 119.154 88.434  1.00 249.04 ? 546 ASN B N   1 
ATOM   5443  C CA  . ASN B 2 524 ? 186.293 119.905 89.044  1.00 249.04 ? 546 ASN B CA  1 
ATOM   5444  C C   . ASN B 2 524 ? 184.944 119.532 88.434  1.00 249.04 ? 546 ASN B C   1 
ATOM   5445  O O   . ASN B 2 524 ? 184.035 120.362 88.354  1.00 249.04 ? 546 ASN B O   1 
ATOM   5446  C CB  . ASN B 2 524 ? 186.524 121.416 88.947  1.00 249.04 ? 546 ASN B CB  1 
ATOM   5447  C CG  . ASN B 2 524 ? 187.791 121.859 89.653  1.00 249.04 ? 546 ASN B CG  1 
ATOM   5448  O OD1 . ASN B 2 524 ? 188.225 121.237 90.622  1.00 249.04 ? 546 ASN B OD1 1 
ATOM   5449  N ND2 . ASN B 2 524 ? 188.393 122.939 89.167  1.00 249.04 ? 546 ASN B ND2 1 
ATOM   5450  N N   . GLY B 2 525 ? 184.806 118.291 88.002  1.00 249.12 ? 547 GLY B N   1 
ATOM   5451  C CA  . GLY B 2 525 ? 183.568 117.824 87.412  1.00 249.12 ? 547 GLY B CA  1 
ATOM   5452  C C   . GLY B 2 525 ? 183.836 116.698 86.436  1.00 249.12 ? 547 GLY B C   1 
ATOM   5453  O O   . GLY B 2 525 ? 184.977 116.348 86.148  1.00 249.12 ? 547 GLY B O   1 
ATOM   5454  N N   . PHE B 2 526 ? 182.743 116.135 85.927  1.00 248.14 ? 548 PHE B N   1 
ATOM   5455  C CA  . PHE B 2 526 ? 182.822 115.051 84.957  1.00 248.14 ? 548 PHE B CA  1 
ATOM   5456  C C   . PHE B 2 526 ? 183.042 115.630 83.565  1.00 248.14 ? 548 PHE B C   1 
ATOM   5457  O O   . PHE B 2 526 ? 182.237 116.438 83.088  1.00 248.14 ? 548 PHE B O   1 
ATOM   5458  C CB  . PHE B 2 526 ? 181.552 114.205 84.993  1.00 248.14 ? 548 PHE B CB  1 
ATOM   5459  C CG  . PHE B 2 526 ? 181.479 113.269 86.165  1.00 248.14 ? 548 PHE B CG  1 
ATOM   5460  C CD1 . PHE B 2 526 ? 182.248 112.117 86.196  1.00 248.14 ? 548 PHE B CD1 1 
ATOM   5461  C CD2 . PHE B 2 526 ? 180.641 113.538 87.233  1.00 248.14 ? 548 PHE B CD2 1 
ATOM   5462  C CE1 . PHE B 2 526 ? 182.183 111.253 87.272  1.00 248.14 ? 548 PHE B CE1 1 
ATOM   5463  C CE2 . PHE B 2 526 ? 180.571 112.677 88.312  1.00 248.14 ? 548 PHE B CE2 1 
ATOM   5464  C CZ  . PHE B 2 526 ? 181.344 111.533 88.331  1.00 248.14 ? 548 PHE B CZ  1 
ATOM   5465  N N   . ILE B 2 527 ? 184.130 115.217 82.914  1.00 254.92 ? 549 ILE B N   1 
ATOM   5466  C CA  . ILE B 2 527 ? 184.429 115.708 81.576  1.00 254.92 ? 549 ILE B CA  1 
ATOM   5467  C C   . ILE B 2 527 ? 183.463 115.084 80.577  1.00 254.92 ? 549 ILE B C   1 
ATOM   5468  O O   . ILE B 2 527 ? 183.104 113.903 80.680  1.00 254.92 ? 549 ILE B O   1 
ATOM   5469  C CB  . ILE B 2 527 ? 185.896 115.415 81.213  1.00 254.92 ? 549 ILE B CB  1 
ATOM   5470  C CG1 . ILE B 2 527 ? 186.258 116.045 79.865  1.00 254.92 ? 549 ILE B CG1 1 
ATOM   5471  C CG2 . ILE B 2 527 ? 186.172 113.915 81.215  1.00 254.92 ? 549 ILE B CG2 1 
ATOM   5472  C CD1 . ILE B 2 527 ? 186.171 117.555 79.857  1.00 254.92 ? 549 ILE B CD1 1 
ATOM   5473  N N   . ARG B 2 528 ? 183.019 115.885 79.611  1.00 260.85 ? 550 ARG B N   1 
ATOM   5474  C CA  . ARG B 2 528 ? 182.055 115.449 78.608  1.00 260.85 ? 550 ARG B CA  1 
ATOM   5475  C C   . ARG B 2 528 ? 182.637 115.357 77.208  1.00 260.85 ? 550 ARG B C   1 
ATOM   5476  O O   . ARG B 2 528 ? 182.362 114.390 76.495  1.00 260.85 ? 550 ARG B O   1 
ATOM   5477  C CB  . ARG B 2 528 ? 180.850 116.397 78.587  1.00 260.85 ? 550 ARG B CB  1 
ATOM   5478  C CG  . ARG B 2 528 ? 180.224 116.630 79.951  1.00 260.85 ? 550 ARG B CG  1 
ATOM   5479  C CD  . ARG B 2 528 ? 179.792 115.322 80.593  1.00 260.85 ? 550 ARG B CD  1 
ATOM   5480  N NE  . ARG B 2 528 ? 179.162 115.535 81.892  1.00 260.85 ? 550 ARG B NE  1 
ATOM   5481  C CZ  . ARG B 2 528 ? 178.724 114.557 82.679  1.00 260.85 ? 550 ARG B CZ  1 
ATOM   5482  N NH1 . ARG B 2 528 ? 178.847 113.292 82.299  1.00 260.85 ? 550 ARG B NH1 1 
ATOM   5483  N NH2 . ARG B 2 528 ? 178.162 114.843 83.845  1.00 260.85 ? 550 ARG B NH2 1 
ATOM   5484  N N   . ASN B 2 529 ? 183.437 116.336 76.794  1.00 270.13 ? 551 ASN B N   1 
ATOM   5485  C CA  . ASN B 2 529 ? 184.015 116.348 75.458  1.00 270.13 ? 551 ASN B CA  1 
ATOM   5486  C C   . ASN B 2 529 ? 185.334 117.112 75.510  1.00 270.13 ? 551 ASN B C   1 
ATOM   5487  O O   . ASN B 2 529 ? 185.776 117.553 76.575  1.00 270.13 ? 551 ASN B O   1 
ATOM   5488  C CB  . ASN B 2 529 ? 183.029 116.952 74.448  1.00 270.13 ? 551 ASN B CB  1 
ATOM   5489  C CG  . ASN B 2 529 ? 182.532 118.327 74.863  1.00 270.13 ? 551 ASN B CG  1 
ATOM   5490  O OD1 . ASN B 2 529 ? 183.094 118.964 75.754  1.00 270.13 ? 551 ASN B OD1 1 
ATOM   5491  N ND2 . ASN B 2 529 ? 181.471 118.793 74.213  1.00 270.13 ? 551 ASN B ND2 1 
ATOM   5492  N N   . TYR B 2 530 ? 185.963 117.272 74.347  1.00 275.20 ? 552 TYR B N   1 
ATOM   5493  C CA  . TYR B 2 530 ? 187.205 118.023 74.225  1.00 275.20 ? 552 TYR B CA  1 
ATOM   5494  C C   . TYR B 2 530 ? 187.157 118.835 72.941  1.00 275.20 ? 552 TYR B C   1 
ATOM   5495  O O   . TYR B 2 530 ? 186.867 118.291 71.872  1.00 275.20 ? 552 TYR B O   1 
ATOM   5496  C CB  . TYR B 2 530 ? 188.424 117.093 74.222  1.00 275.20 ? 552 TYR B CB  1 
ATOM   5497  C CG  . TYR B 2 530 ? 188.833 116.606 75.594  1.00 275.20 ? 552 TYR B CG  1 
ATOM   5498  C CD1 . TYR B 2 530 ? 188.913 117.482 76.669  1.00 275.20 ? 552 TYR B CD1 1 
ATOM   5499  C CD2 . TYR B 2 530 ? 189.143 115.270 75.814  1.00 275.20 ? 552 TYR B CD2 1 
ATOM   5500  C CE1 . TYR B 2 530 ? 189.288 117.041 77.924  1.00 275.20 ? 552 TYR B CE1 1 
ATOM   5501  C CE2 . TYR B 2 530 ? 189.519 114.820 77.066  1.00 275.20 ? 552 TYR B CE2 1 
ATOM   5502  C CZ  . TYR B 2 530 ? 189.590 115.710 78.117  1.00 275.20 ? 552 TYR B CZ  1 
ATOM   5503  O OH  . TYR B 2 530 ? 189.963 115.266 79.365  1.00 275.20 ? 552 TYR B OH  1 
ATOM   5504  N N   . SER B 2 531 ? 187.439 120.129 73.049  1.00 277.40 ? 553 SER B N   1 
ATOM   5505  C CA  . SER B 2 531 ? 187.397 121.044 71.916  1.00 277.40 ? 553 SER B CA  1 
ATOM   5506  C C   . SER B 2 531 ? 188.814 121.354 71.459  1.00 277.40 ? 553 SER B C   1 
ATOM   5507  O O   . SER B 2 531 ? 189.658 121.757 72.266  1.00 277.40 ? 553 SER B O   1 
ATOM   5508  C CB  . SER B 2 531 ? 186.662 122.335 72.281  1.00 277.40 ? 553 SER B CB  1 
ATOM   5509  O OG  . SER B 2 531 ? 185.462 122.058 72.982  1.00 277.40 ? 553 SER B OG  1 
ATOM   5510  N N   . ILE B 2 532 ? 189.071 121.162 70.168  1.00 283.16 ? 554 ILE B N   1 
ATOM   5511  C CA  . ILE B 2 532 ? 190.374 121.423 69.566  1.00 283.16 ? 554 ILE B CA  1 
ATOM   5512  C C   . ILE B 2 532 ? 190.218 122.582 68.592  1.00 283.16 ? 554 ILE B C   1 
ATOM   5513  O O   . ILE B 2 532 ? 189.486 122.475 67.600  1.00 283.16 ? 554 ILE B O   1 
ATOM   5514  C CB  . ILE B 2 532 ? 190.932 120.178 68.860  1.00 283.16 ? 554 ILE B CB  1 
ATOM   5515  C CG1 . ILE B 2 532 ? 191.055 119.015 69.846  1.00 283.16 ? 554 ILE B CG1 1 
ATOM   5516  C CG2 . ILE B 2 532 ? 192.277 120.487 68.221  1.00 283.16 ? 554 ILE B CG2 1 
ATOM   5517  C CD1 . ILE B 2 532 ? 191.514 117.723 69.209  1.00 283.16 ? 554 ILE B CD1 1 
ATOM   5518  N N   . SER B 2 533 ? 190.905 123.686 68.873  1.00 286.32 ? 555 SER B N   1 
ATOM   5519  C CA  . SER B 2 533 ? 190.860 124.879 68.041  1.00 286.32 ? 555 SER B CA  1 
ATOM   5520  C C   . SER B 2 533 ? 192.245 125.162 67.477  1.00 286.32 ? 555 SER B C   1 
ATOM   5521  O O   . SER B 2 533 ? 193.251 125.031 68.182  1.00 286.32 ? 555 SER B O   1 
ATOM   5522  C CB  . SER B 2 533 ? 190.359 126.088 68.837  1.00 286.32 ? 555 SER B CB  1 
ATOM   5523  O OG  . SER B 2 533 ? 191.270 126.437 69.864  1.00 286.32 ? 555 SER B OG  1 
ATOM   5524  N N   . TYR B 2 534 ? 192.293 125.549 66.204  1.00 287.99 ? 556 TYR B N   1 
ATOM   5525  C CA  . TYR B 2 534 ? 193.556 125.812 65.533  1.00 287.99 ? 556 TYR B CA  1 
ATOM   5526  C C   . TYR B 2 534 ? 193.339 126.843 64.435  1.00 287.99 ? 556 TYR B C   1 
ATOM   5527  O O   . TYR B 2 534 ? 192.276 126.894 63.811  1.00 287.99 ? 556 TYR B O   1 
ATOM   5528  C CB  . TYR B 2 534 ? 194.161 124.530 64.945  1.00 287.99 ? 556 TYR B CB  1 
ATOM   5529  C CG  . TYR B 2 534 ? 193.271 123.827 63.944  1.00 287.99 ? 556 TYR B CG  1 
ATOM   5530  C CD1 . TYR B 2 534 ? 192.255 122.978 64.365  1.00 287.99 ? 556 TYR B CD1 1 
ATOM   5531  C CD2 . TYR B 2 534 ? 193.450 124.006 62.579  1.00 287.99 ? 556 TYR B CD2 1 
ATOM   5532  C CE1 . TYR B 2 534 ? 191.440 122.333 63.455  1.00 287.99 ? 556 TYR B CE1 1 
ATOM   5533  C CE2 . TYR B 2 534 ? 192.640 123.364 61.661  1.00 287.99 ? 556 TYR B CE2 1 
ATOM   5534  C CZ  . TYR B 2 534 ? 191.637 122.529 62.105  1.00 287.99 ? 556 TYR B CZ  1 
ATOM   5535  O OH  . TYR B 2 534 ? 190.828 121.887 61.197  1.00 287.99 ? 556 TYR B OH  1 
ATOM   5536  N N   . ARG B 2 535 ? 194.363 127.663 64.207  1.00 282.34 ? 557 ARG B N   1 
ATOM   5537  C CA  . ARG B 2 535 ? 194.317 128.690 63.177  1.00 282.34 ? 557 ARG B CA  1 
ATOM   5538  C C   . ARG B 2 535 ? 195.738 129.125 62.856  1.00 282.34 ? 557 ARG B C   1 
ATOM   5539  O O   . ARG B 2 535 ? 196.579 129.222 63.754  1.00 282.34 ? 557 ARG B O   1 
ATOM   5540  C CB  . ARG B 2 535 ? 193.481 129.896 63.624  1.00 282.34 ? 557 ARG B CB  1 
ATOM   5541  C CG  . ARG B 2 535 ? 193.234 130.924 62.532  1.00 282.34 ? 557 ARG B CG  1 
ATOM   5542  C CD  . ARG B 2 535 ? 192.964 132.302 63.116  1.00 282.34 ? 557 ARG B CD  1 
ATOM   5543  N NE  . ARG B 2 535 ? 194.197 132.986 63.496  1.00 282.34 ? 557 ARG B NE  1 
ATOM   5544  C CZ  . ARG B 2 535 ? 194.661 133.054 64.740  1.00 282.34 ? 557 ARG B CZ  1 
ATOM   5545  N NH1 . ARG B 2 535 ? 193.994 132.480 65.731  1.00 282.34 ? 557 ARG B NH1 1 
ATOM   5546  N NH2 . ARG B 2 535 ? 195.792 133.698 64.993  1.00 282.34 ? 557 ARG B NH2 1 
ATOM   5547  N N   . THR B 2 536 ? 195.997 129.385 61.578  1.00 277.84 ? 558 THR B N   1 
ATOM   5548  C CA  . THR B 2 536 ? 197.299 129.863 61.142  1.00 277.84 ? 558 THR B CA  1 
ATOM   5549  C C   . THR B 2 536 ? 197.323 131.392 61.199  1.00 277.84 ? 558 THR B C   1 
ATOM   5550  O O   . THR B 2 536 ? 196.423 132.029 61.752  1.00 277.84 ? 558 THR B O   1 
ATOM   5551  C CB  . THR B 2 536 ? 197.627 129.318 59.751  1.00 277.84 ? 558 THR B CB  1 
ATOM   5552  O OG1 . THR B 2 536 ? 198.987 129.627 59.421  1.00 277.84 ? 558 THR B OG1 1 
ATOM   5553  C CG2 . THR B 2 536 ? 196.706 129.912 58.702  1.00 277.84 ? 558 THR B CG2 1 
ATOM   5554  N N   . SER B 2 537 ? 198.365 131.999 60.625  1.00 275.32 ? 559 SER B N   1 
ATOM   5555  C CA  . SER B 2 537 ? 198.559 133.438 60.774  1.00 275.32 ? 559 SER B CA  1 
ATOM   5556  C C   . SER B 2 537 ? 197.537 134.246 59.982  1.00 275.32 ? 559 SER B C   1 
ATOM   5557  O O   . SER B 2 537 ? 197.200 135.367 60.380  1.00 275.32 ? 559 SER B O   1 
ATOM   5558  C CB  . SER B 2 537 ? 199.976 133.821 60.349  1.00 275.32 ? 559 SER B CB  1 
ATOM   5559  O OG  . SER B 2 537 ? 200.942 133.056 61.049  1.00 275.32 ? 559 SER B OG  1 
ATOM   5560  N N   . VAL B 2 538 ? 197.035 133.709 58.872  1.00 275.99 ? 560 VAL B N   1 
ATOM   5561  C CA  . VAL B 2 538 ? 196.143 134.468 58.001  1.00 275.99 ? 560 VAL B CA  1 
ATOM   5562  C C   . VAL B 2 538 ? 194.854 133.695 57.754  1.00 275.99 ? 560 VAL B C   1 
ATOM   5563  O O   . VAL B 2 538 ? 193.932 134.196 57.100  1.00 275.99 ? 560 VAL B O   1 
ATOM   5564  C CB  . VAL B 2 538 ? 196.834 134.814 56.670  1.00 275.99 ? 560 VAL B CB  1 
ATOM   5565  C CG1 . VAL B 2 538 ? 197.865 135.915 56.877  1.00 275.99 ? 560 VAL B CG1 1 
ATOM   5566  C CG2 . VAL B 2 538 ? 197.481 133.575 56.071  1.00 275.99 ? 560 VAL B CG2 1 
ATOM   5567  N N   . GLY B 2 539 ? 194.779 132.472 58.273  1.00 281.39 ? 561 GLY B N   1 
ATOM   5568  C CA  . GLY B 2 539 ? 193.622 131.630 58.064  1.00 281.39 ? 561 GLY B CA  1 
ATOM   5569  C C   . GLY B 2 539 ? 192.477 131.953 59.003  1.00 281.39 ? 561 GLY B C   1 
ATOM   5570  O O   . GLY B 2 539 ? 192.536 132.863 59.831  1.00 281.39 ? 561 GLY B O   1 
ATOM   5571  N N   . LYS B 2 540 ? 191.408 131.179 58.861  1.00 286.36 ? 562 LYS B N   1 
ATOM   5572  C CA  . LYS B 2 540 ? 190.208 131.333 59.668  1.00 286.36 ? 562 LYS B CA  1 
ATOM   5573  C C   . LYS B 2 540 ? 190.216 130.349 60.833  1.00 286.36 ? 562 LYS B C   1 
ATOM   5574  O O   . LYS B 2 540 ? 190.883 129.312 60.801  1.00 286.36 ? 562 LYS B O   1 
ATOM   5575  C CB  . LYS B 2 540 ? 188.952 131.136 58.810  1.00 286.36 ? 562 LYS B CB  1 
ATOM   5576  C CG  . LYS B 2 540 ? 188.794 129.743 58.208  1.00 286.36 ? 562 LYS B CG  1 
ATOM   5577  C CD  . LYS B 2 540 ? 187.879 128.859 59.047  1.00 286.36 ? 562 LYS B CD  1 
ATOM   5578  C CE  . LYS B 2 540 ? 187.555 127.559 58.330  1.00 286.36 ? 562 LYS B CE  1 
ATOM   5579  N NZ  . LYS B 2 540 ? 186.799 126.618 59.202  1.00 286.36 ? 562 LYS B NZ  1 
ATOM   5580  N N   . GLU B 2 541 ? 189.458 130.692 61.871  1.00 287.71 ? 563 GLU B N   1 
ATOM   5581  C CA  . GLU B 2 541 ? 189.362 129.855 63.060  1.00 287.71 ? 563 GLU B CA  1 
ATOM   5582  C C   . GLU B 2 541 ? 188.453 128.664 62.780  1.00 287.71 ? 563 GLU B C   1 
ATOM   5583  O O   . GLU B 2 541 ? 187.304 128.837 62.359  1.00 287.71 ? 563 GLU B O   1 
ATOM   5584  C CB  . GLU B 2 541 ? 188.837 130.667 64.243  1.00 287.71 ? 563 GLU B CB  1 
ATOM   5585  C CG  . GLU B 2 541 ? 188.670 129.868 65.531  1.00 287.71 ? 563 GLU B CG  1 
ATOM   5586  C CD  . GLU B 2 541 ? 189.861 128.979 65.844  1.00 287.71 ? 563 GLU B CD  1 
ATOM   5587  O OE1 . GLU B 2 541 ? 191.014 129.422 65.651  1.00 287.71 ? 563 GLU B OE1 1 
ATOM   5588  O OE2 . GLU B 2 541 ? 189.642 127.829 66.276  1.00 287.71 ? 563 GLU B OE2 1 
ATOM   5589  N N   . MET B 2 542 ? 188.967 127.459 63.012  1.00 285.43 ? 564 MET B N   1 
ATOM   5590  C CA  . MET B 2 542 ? 188.212 126.226 62.842  1.00 285.43 ? 564 MET B CA  1 
ATOM   5591  C C   . MET B 2 542 ? 188.265 125.433 64.139  1.00 285.43 ? 564 MET B C   1 
ATOM   5592  O O   . MET B 2 542 ? 189.351 125.160 64.660  1.00 285.43 ? 564 MET B O   1 
ATOM   5593  C CB  . MET B 2 542 ? 188.764 125.395 61.681  1.00 285.43 ? 564 MET B CB  1 
ATOM   5594  C CG  . MET B 2 542 ? 188.088 124.045 61.506  1.00 285.43 ? 564 MET B CG  1 
ATOM   5595  S SD  . MET B 2 542 ? 187.926 123.566 59.775  1.00 285.43 ? 564 MET B SD  1 
ATOM   5596  C CE  . MET B 2 542 ? 189.519 124.070 59.129  1.00 285.43 ? 564 MET B CE  1 
ATOM   5597  N N   . VAL B 2 543 ? 187.094 125.067 64.656  1.00 283.37 ? 565 VAL B N   1 
ATOM   5598  C CA  . VAL B 2 543 ? 186.971 124.370 65.930  1.00 283.37 ? 565 VAL B CA  1 
ATOM   5599  C C   . VAL B 2 543 ? 186.350 123.003 65.678  1.00 283.37 ? 565 VAL B C   1 
ATOM   5600  O O   . VAL B 2 543 ? 185.316 122.899 65.009  1.00 283.37 ? 565 VAL B O   1 
ATOM   5601  C CB  . VAL B 2 543 ? 186.127 125.174 66.937  1.00 283.37 ? 565 VAL B CB  1 
ATOM   5602  C CG1 . VAL B 2 543 ? 185.930 124.381 68.221  1.00 283.37 ? 565 VAL B CG1 1 
ATOM   5603  C CG2 . VAL B 2 543 ? 186.780 126.516 67.226  1.00 283.37 ? 565 VAL B CG2 1 
ATOM   5604  N N   . VAL B 2 544 ? 186.982 121.961 66.215  1.00 281.31 ? 566 VAL B N   1 
ATOM   5605  C CA  . VAL B 2 544 ? 186.453 120.607 66.164  1.00 281.31 ? 566 VAL B CA  1 
ATOM   5606  C C   . VAL B 2 544 ? 186.282 120.106 67.592  1.00 281.31 ? 566 VAL B C   1 
ATOM   5607  O O   . VAL B 2 544 ? 186.931 120.582 68.528  1.00 281.31 ? 566 VAL B O   1 
ATOM   5608  C CB  . VAL B 2 544 ? 187.353 119.653 65.351  1.00 281.31 ? 566 VAL B CB  1 
ATOM   5609  C CG1 . VAL B 2 544 ? 187.457 120.123 63.908  1.00 281.31 ? 566 VAL B CG1 1 
ATOM   5610  C CG2 . VAL B 2 544 ? 188.731 119.552 65.983  1.00 281.31 ? 566 VAL B CG2 1 
ATOM   5611  N N   . HIS B 2 545 ? 185.390 119.131 67.753  1.00 278.45 ? 567 HIS B N   1 
ATOM   5612  C CA  . HIS B 2 545 ? 185.056 118.587 69.062  1.00 278.45 ? 567 HIS B CA  1 
ATOM   5613  C C   . HIS B 2 545 ? 185.264 117.081 69.054  1.00 278.45 ? 567 HIS B C   1 
ATOM   5614  O O   . HIS B 2 545 ? 184.794 116.390 68.145  1.00 278.45 ? 567 HIS B O   1 
ATOM   5615  C CB  . HIS B 2 545 ? 183.611 118.922 69.447  1.00 278.45 ? 567 HIS B CB  1 
ATOM   5616  C CG  . HIS B 2 545 ? 183.322 120.390 69.488  1.00 278.45 ? 567 HIS B CG  1 
ATOM   5617  N ND1 . HIS B 2 545 ? 183.491 121.151 70.624  1.00 278.45 ? 567 HIS B ND1 1 
ATOM   5618  C CD2 . HIS B 2 545 ? 182.876 121.238 68.531  1.00 278.45 ? 567 HIS B CD2 1 
ATOM   5619  C CE1 . HIS B 2 545 ? 183.161 122.404 70.366  1.00 278.45 ? 567 HIS B CE1 1 
ATOM   5620  N NE2 . HIS B 2 545 ? 182.784 122.484 69.103  1.00 278.45 ? 567 HIS B NE2 1 
ATOM   5621  N N   . VAL B 2 546 ? 185.969 116.578 70.066  1.00 277.80 ? 568 VAL B N   1 
ATOM   5622  C CA  . VAL B 2 546 ? 186.219 115.153 70.223  1.00 277.80 ? 568 VAL B CA  1 
ATOM   5623  C C   . VAL B 2 546 ? 185.773 114.729 71.615  1.00 277.80 ? 568 VAL B C   1 
ATOM   5624  O O   . VAL B 2 546 ? 185.762 115.529 72.556  1.00 277.80 ? 568 VAL B O   1 
ATOM   5625  C CB  . VAL B 2 546 ? 187.704 114.796 69.992  1.00 277.80 ? 568 VAL B CB  1 
ATOM   5626  C CG1 . VAL B 2 546 ? 188.042 114.879 68.514  1.00 277.80 ? 568 VAL B CG1 1 
ATOM   5627  C CG2 . VAL B 2 546 ? 188.604 115.714 70.802  1.00 277.80 ? 568 VAL B CG2 1 
ATOM   5628  N N   . ASP B 2 547 ? 185.399 113.458 71.739  1.00 271.75 ? 569 ASP B N   1 
ATOM   5629  C CA  . ASP B 2 547 ? 184.926 112.936 73.010  1.00 271.75 ? 569 ASP B CA  1 
ATOM   5630  C C   . ASP B 2 547 ? 186.084 112.813 74.002  1.00 271.75 ? 569 ASP B C   1 
ATOM   5631  O O   . ASP B 2 547 ? 187.263 112.884 73.643  1.00 271.75 ? 569 ASP B O   1 
ATOM   5632  C CB  . ASP B 2 547 ? 184.246 111.582 72.811  1.00 271.75 ? 569 ASP B CB  1 
ATOM   5633  C CG  . ASP B 2 547 ? 183.246 111.263 73.906  1.00 271.75 ? 569 ASP B CG  1 
ATOM   5634  O OD1 . ASP B 2 547 ? 182.347 110.429 73.666  1.00 271.75 ? 569 ASP B OD1 1 
ATOM   5635  O OD2 . ASP B 2 547 ? 183.356 111.846 75.005  1.00 271.75 ? 569 ASP B OD2 1 
ATOM   5636  N N   . SER B 2 548 ? 185.727 112.623 75.274  1.00 268.30 ? 570 SER B N   1 
ATOM   5637  C CA  . SER B 2 548 ? 186.735 112.492 76.320  1.00 268.30 ? 570 SER B CA  1 
ATOM   5638  C C   . SER B 2 548 ? 187.434 111.141 76.287  1.00 268.30 ? 570 SER B C   1 
ATOM   5639  O O   . SER B 2 548 ? 188.554 111.025 76.796  1.00 268.30 ? 570 SER B O   1 
ATOM   5640  C CB  . SER B 2 548 ? 186.099 112.712 77.693  1.00 268.30 ? 570 SER B CB  1 
ATOM   5641  O OG  . SER B 2 548 ? 185.241 113.838 77.683  1.00 268.30 ? 570 SER B OG  1 
ATOM   5642  N N   . SER B 2 549 ? 186.804 110.120 75.703  1.00 273.20 ? 571 SER B N   1 
ATOM   5643  C CA  . SER B 2 549 ? 187.409 108.796 75.640  1.00 273.20 ? 571 SER B CA  1 
ATOM   5644  C C   . SER B 2 549 ? 188.558 108.717 74.644  1.00 273.20 ? 571 SER B C   1 
ATOM   5645  O O   . SER B 2 549 ? 189.285 107.718 74.645  1.00 273.20 ? 571 SER B O   1 
ATOM   5646  C CB  . SER B 2 549 ? 186.348 107.752 75.285  1.00 273.20 ? 571 SER B CB  1 
ATOM   5647  O OG  . SER B 2 549 ? 185.166 107.948 76.042  1.00 273.20 ? 571 SER B OG  1 
ATOM   5648  N N   . HIS B 2 550 ? 188.740 109.731 73.804  1.00 273.83 ? 572 HIS B N   1 
ATOM   5649  C CA  . HIS B 2 550 ? 189.807 109.748 72.816  1.00 273.83 ? 572 HIS B CA  1 
ATOM   5650  C C   . HIS B 2 550 ? 190.974 110.588 73.316  1.00 273.83 ? 572 HIS B C   1 
ATOM   5651  O O   . HIS B 2 550 ? 190.779 111.625 73.957  1.00 273.83 ? 572 HIS B O   1 
ATOM   5652  C CB  . HIS B 2 550 ? 189.306 110.298 71.479  1.00 273.83 ? 572 HIS B CB  1 
ATOM   5653  C CG  . HIS B 2 550 ? 188.199 109.494 70.871  1.00 273.83 ? 572 HIS B CG  1 
ATOM   5654  N ND1 . HIS B 2 550 ? 186.908 109.522 71.352  1.00 273.83 ? 572 HIS B ND1 1 
ATOM   5655  C CD2 . HIS B 2 550 ? 188.191 108.639 69.821  1.00 273.83 ? 572 HIS B CD2 1 
ATOM   5656  C CE1 . HIS B 2 550 ? 186.152 108.720 70.624  1.00 273.83 ? 572 HIS B CE1 1 
ATOM   5657  N NE2 . HIS B 2 550 ? 186.906 108.172 69.689  1.00 273.83 ? 572 HIS B NE2 1 
ATOM   5658  N N   . THR B 2 551 ? 192.188 110.132 73.019  1.00 279.95 ? 573 THR B N   1 
ATOM   5659  C CA  . THR B 2 551 ? 193.413 110.843 73.367  1.00 279.95 ? 573 THR B CA  1 
ATOM   5660  C C   . THR B 2 551 ? 194.188 111.320 72.150  1.00 279.95 ? 573 THR B C   1 
ATOM   5661  O O   . THR B 2 551 ? 194.719 112.432 72.158  1.00 279.95 ? 573 THR B O   1 
ATOM   5662  C CB  . THR B 2 551 ? 194.316 109.949 74.227  1.00 279.95 ? 573 THR B CB  1 
ATOM   5663  O OG1 . THR B 2 551 ? 193.602 109.530 75.396  1.00 279.95 ? 573 THR B OG1 1 
ATOM   5664  C CG2 . THR B 2 551 ? 195.568 110.701 74.657  1.00 279.95 ? 573 THR B CG2 1 
ATOM   5665  N N   . GLU B 2 552 ? 194.255 110.509 71.099  1.00 280.07 ? 574 GLU B N   1 
ATOM   5666  C CA  . GLU B 2 552 ? 194.904 110.887 69.853  1.00 280.07 ? 574 GLU B CA  1 
ATOM   5667  C C   . GLU B 2 552 ? 193.852 111.258 68.817  1.00 280.07 ? 574 GLU B C   1 
ATOM   5668  O O   . GLU B 2 552 ? 192.824 110.586 68.691  1.00 280.07 ? 574 GLU B O   1 
ATOM   5669  C CB  . GLU B 2 552 ? 195.779 109.748 69.324  1.00 280.07 ? 574 GLU B CB  1 
ATOM   5670  C CG  . GLU B 2 552 ? 196.752 109.185 70.346  1.00 280.07 ? 574 GLU B CG  1 
ATOM   5671  C CD  . GLU B 2 552 ? 197.700 110.235 70.888  1.00 280.07 ? 574 GLU B CD  1 
ATOM   5672  O OE1 . GLU B 2 552 ? 197.633 110.531 72.099  1.00 280.07 ? 574 GLU B OE1 1 
ATOM   5673  O OE2 . GLU B 2 552 ? 198.514 110.765 70.102  1.00 280.07 ? 574 GLU B OE2 1 
ATOM   5674  N N   . TYR B 2 553 ? 194.114 112.332 68.076  1.00 283.50 ? 575 TYR B N   1 
ATOM   5675  C CA  . TYR B 2 553 ? 193.187 112.801 67.052  1.00 283.50 ? 575 TYR B CA  1 
ATOM   5676  C C   . TYR B 2 553 ? 193.988 113.404 65.910  1.00 283.50 ? 575 TYR B C   1 
ATOM   5677  O O   . TYR B 2 553 ? 194.793 114.314 66.129  1.00 283.50 ? 575 TYR B O   1 
ATOM   5678  C CB  . TYR B 2 553 ? 192.204 113.826 67.623  1.00 283.50 ? 575 TYR B CB  1 
ATOM   5679  C CG  . TYR B 2 553 ? 191.274 114.420 66.591  1.00 283.50 ? 575 TYR B CG  1 
ATOM   5680  C CD1 . TYR B 2 553 ? 191.413 115.739 66.179  1.00 283.50 ? 575 TYR B CD1 1 
ATOM   5681  C CD2 . TYR B 2 553 ? 190.260 113.660 66.023  1.00 283.50 ? 575 TYR B CD2 1 
ATOM   5682  C CE1 . TYR B 2 553 ? 190.566 116.287 65.235  1.00 283.50 ? 575 TYR B CE1 1 
ATOM   5683  C CE2 . TYR B 2 553 ? 189.408 114.199 65.077  1.00 283.50 ? 575 TYR B CE2 1 
ATOM   5684  C CZ  . TYR B 2 553 ? 189.565 115.512 64.687  1.00 283.50 ? 575 TYR B CZ  1 
ATOM   5685  O OH  . TYR B 2 553 ? 188.720 116.053 63.746  1.00 283.50 ? 575 TYR B OH  1 
ATOM   5686  N N   . THR B 2 554 ? 193.765 112.899 64.699  1.00 287.29 ? 576 THR B N   1 
ATOM   5687  C CA  . THR B 2 554 ? 194.475 113.369 63.518  1.00 287.29 ? 576 THR B CA  1 
ATOM   5688  C C   . THR B 2 554 ? 193.779 114.600 62.952  1.00 287.29 ? 576 THR B C   1 
ATOM   5689  O O   . THR B 2 554 ? 192.557 114.602 62.769  1.00 287.29 ? 576 THR B O   1 
ATOM   5690  C CB  . THR B 2 554 ? 194.548 112.271 62.457  1.00 287.29 ? 576 THR B CB  1 
ATOM   5691  O OG1 . THR B 2 554 ? 193.308 112.211 61.742  1.00 287.29 ? 576 THR B OG1 1 
ATOM   5692  C CG2 . THR B 2 554 ? 194.818 110.921 63.105  1.00 287.29 ? 576 THR B CG2 1 
ATOM   5693  N N   . LEU B 2 555 ? 194.559 115.642 62.678  1.00 286.55 ? 577 LEU B N   1 
ATOM   5694  C CA  . LEU B 2 555 ? 194.032 116.883 62.124  1.00 286.55 ? 577 LEU B CA  1 
ATOM   5695  C C   . LEU B 2 555 ? 194.229 116.879 60.613  1.00 286.55 ? 577 LEU B C   1 
ATOM   5696  O O   . LEU B 2 555 ? 195.353 116.705 60.128  1.00 286.55 ? 577 LEU B O   1 
ATOM   5697  C CB  . LEU B 2 555 ? 194.715 118.097 62.753  1.00 286.55 ? 577 LEU B CB  1 
ATOM   5698  C CG  . LEU B 2 555 ? 194.139 118.632 64.068  1.00 286.55 ? 577 LEU B CG  1 
ATOM   5699  C CD1 . LEU B 2 555 ? 192.683 119.035 63.889  1.00 286.55 ? 577 LEU B CD1 1 
ATOM   5700  C CD2 . LEU B 2 555 ? 194.290 117.630 65.204  1.00 286.55 ? 577 LEU B CD2 1 
ATOM   5701  N N   . SER B 2 556 ? 193.141 117.070 59.874  1.00 289.18 ? 578 SER B N   1 
ATOM   5702  C CA  . SER B 2 556 ? 193.174 117.083 58.422  1.00 289.18 ? 578 SER B CA  1 
ATOM   5703  C C   . SER B 2 556 ? 193.134 118.521 57.910  1.00 289.18 ? 578 SER B C   1 
ATOM   5704  O O   . SER B 2 556 ? 193.098 119.484 58.680  1.00 289.18 ? 578 SER B O   1 
ATOM   5705  C CB  . SER B 2 556 ? 192.015 116.260 57.856  1.00 289.18 ? 578 SER B CB  1 
ATOM   5706  O OG  . SER B 2 556 ? 191.884 115.025 58.539  1.00 289.18 ? 578 SER B OG  1 
ATOM   5707  N N   . SER B 2 557 ? 193.141 118.657 56.581  1.00 291.67 ? 579 SER B N   1 
ATOM   5708  C CA  . SER B 2 557 ? 193.095 119.957 55.909  1.00 291.67 ? 579 SER B CA  1 
ATOM   5709  C C   . SER B 2 557 ? 194.247 120.855 56.361  1.00 291.67 ? 579 SER B C   1 
ATOM   5710  O O   . SER B 2 557 ? 194.071 122.042 56.641  1.00 291.67 ? 579 SER B O   1 
ATOM   5711  C CB  . SER B 2 557 ? 191.744 120.643 56.127  1.00 291.67 ? 579 SER B CB  1 
ATOM   5712  O OG  . SER B 2 557 ? 190.673 119.735 55.937  1.00 291.67 ? 579 SER B OG  1 
ATOM   5713  N N   . LEU B 2 558 ? 195.441 120.272 56.430  1.00 287.16 ? 580 LEU B N   1 
ATOM   5714  C CA  . LEU B 2 558 ? 196.643 120.987 56.836  1.00 287.16 ? 580 LEU B CA  1 
ATOM   5715  C C   . LEU B 2 558 ? 197.483 121.301 55.604  1.00 287.16 ? 580 LEU B C   1 
ATOM   5716  O O   . LEU B 2 558 ? 197.784 120.406 54.808  1.00 287.16 ? 580 LEU B O   1 
ATOM   5717  C CB  . LEU B 2 558 ? 197.454 120.163 57.838  1.00 287.16 ? 580 LEU B CB  1 
ATOM   5718  C CG  . LEU B 2 558 ? 198.822 120.696 58.273  1.00 287.16 ? 580 LEU B CG  1 
ATOM   5719  C CD1 . LEU B 2 558 ? 198.753 122.177 58.622  1.00 287.16 ? 580 LEU B CD1 1 
ATOM   5720  C CD2 . LEU B 2 558 ? 199.363 119.892 59.444  1.00 287.16 ? 580 LEU B CD2 1 
ATOM   5721  N N   . SER B 2 559 ? 197.857 122.569 55.453  1.00 282.92 ? 581 SER B N   1 
ATOM   5722  C CA  . SER B 2 559 ? 198.674 123.004 54.332  1.00 282.92 ? 581 SER B CA  1 
ATOM   5723  C C   . SER B 2 559 ? 200.149 122.979 54.710  1.00 282.92 ? 581 SER B C   1 
ATOM   5724  O O   . SER B 2 559 ? 200.517 123.288 55.847  1.00 282.92 ? 581 SER B O   1 
ATOM   5725  C CB  . SER B 2 559 ? 198.276 124.412 53.885  1.00 282.92 ? 581 SER B CB  1 
ATOM   5726  O OG  . SER B 2 559 ? 199.332 125.038 53.177  1.00 282.92 ? 581 SER B OG  1 
ATOM   5727  N N   . SER B 2 560 ? 200.989 122.609 53.749  1.00 280.24 ? 582 SER B N   1 
ATOM   5728  C CA  . SER B 2 560 ? 202.422 122.563 53.980  1.00 280.24 ? 582 SER B CA  1 
ATOM   5729  C C   . SER B 2 560 ? 203.022 123.965 53.912  1.00 280.24 ? 582 SER B C   1 
ATOM   5730  O O   . SER B 2 560 ? 202.464 124.880 53.300  1.00 280.24 ? 582 SER B O   1 
ATOM   5731  C CB  . SER B 2 560 ? 203.104 121.648 52.963  1.00 280.24 ? 582 SER B CB  1 
ATOM   5732  O OG  . SER B 2 560 ? 204.388 121.255 53.413  1.00 280.24 ? 582 SER B OG  1 
ATOM   5733  N N   . ASP B 2 561 ? 204.181 124.118 54.558  1.00 280.39 ? 583 ASP B N   1 
ATOM   5734  C CA  . ASP B 2 561 ? 204.898 125.393 54.627  1.00 280.39 ? 583 ASP B CA  1 
ATOM   5735  C C   . ASP B 2 561 ? 204.005 126.481 55.226  1.00 280.39 ? 583 ASP B C   1 
ATOM   5736  O O   . ASP B 2 561 ? 203.924 127.601 54.720  1.00 280.39 ? 583 ASP B O   1 
ATOM   5737  C CB  . ASP B 2 561 ? 205.439 125.796 53.248  1.00 280.39 ? 583 ASP B CB  1 
ATOM   5738  C CG  . ASP B 2 561 ? 206.446 126.940 53.312  1.00 280.39 ? 583 ASP B CG  1 
ATOM   5739  O OD1 . ASP B 2 561 ? 207.661 126.655 53.360  1.00 280.39 ? 583 ASP B OD1 1 
ATOM   5740  O OD2 . ASP B 2 561 ? 206.035 128.119 53.280  1.00 280.39 ? 583 ASP B OD2 1 
ATOM   5741  N N   . THR B 2 562 ? 203.306 126.138 56.306  1.00 278.03 ? 584 THR B N   1 
ATOM   5742  C CA  . THR B 2 562 ? 202.426 127.073 56.996  1.00 278.03 ? 584 THR B CA  1 
ATOM   5743  C C   . THR B 2 562 ? 202.545 126.859 58.495  1.00 278.03 ? 584 THR B C   1 
ATOM   5744  O O   . THR B 2 562 ? 202.419 125.728 58.974  1.00 278.03 ? 584 THR B O   1 
ATOM   5745  C CB  . THR B 2 562 ? 200.964 126.899 56.562  1.00 278.03 ? 584 THR B CB  1 
ATOM   5746  O OG1 . THR B 2 562 ? 200.652 125.504 56.474  1.00 278.03 ? 584 THR B OG1 1 
ATOM   5747  C CG2 . THR B 2 562 ? 200.717 127.559 55.213  1.00 278.03 ? 584 THR B CG2 1 
ATOM   5748  N N   . LEU B 2 563 ? 202.783 127.941 59.231  1.00 270.45 ? 585 LEU B N   1 
ATOM   5749  C CA  . LEU B 2 563 ? 202.842 127.868 60.684  1.00 270.45 ? 585 LEU B CA  1 
ATOM   5750  C C   . LEU B 2 563 ? 201.434 127.836 61.262  1.00 270.45 ? 585 LEU B C   1 
ATOM   5751  O O   . LEU B 2 563 ? 200.571 128.627 60.874  1.00 270.45 ? 585 LEU B O   1 
ATOM   5752  C CB  . LEU B 2 563 ? 203.619 129.055 61.256  1.00 270.45 ? 585 LEU B CB  1 
ATOM   5753  C CG  . LEU B 2 563 ? 205.151 128.996 61.276  1.00 270.45 ? 585 LEU B CG  1 
ATOM   5754  C CD1 . LEU B 2 563 ? 205.629 127.891 62.207  1.00 270.45 ? 585 LEU B CD1 1 
ATOM   5755  C CD2 . LEU B 2 563 ? 205.749 128.829 59.882  1.00 270.45 ? 585 LEU B CD2 1 
ATOM   5756  N N   . TYR B 2 564 ? 201.207 126.919 62.199  1.00 273.51 ? 586 TYR B N   1 
ATOM   5757  C CA  . TYR B 2 564 ? 199.889 126.710 62.780  1.00 273.51 ? 586 TYR B CA  1 
ATOM   5758  C C   . TYR B 2 564 ? 199.971 126.764 64.297  1.00 273.51 ? 586 TYR B C   1 
ATOM   5759  O O   . TYR B 2 564 ? 200.886 126.196 64.901  1.00 273.51 ? 586 TYR B O   1 
ATOM   5760  C CB  . TYR B 2 564 ? 199.293 125.367 62.337  1.00 273.51 ? 586 TYR B CB  1 
ATOM   5761  C CG  . TYR B 2 564 ? 198.396 125.464 61.123  1.00 273.51 ? 586 TYR B CG  1 
ATOM   5762  C CD1 . TYR B 2 564 ? 197.016 125.366 61.245  1.00 273.51 ? 586 TYR B CD1 1 
ATOM   5763  C CD2 . TYR B 2 564 ? 198.929 125.654 59.855  1.00 273.51 ? 586 TYR B CD2 1 
ATOM   5764  C CE1 . TYR B 2 564 ? 196.192 125.454 60.138  1.00 273.51 ? 586 TYR B CE1 1 
ATOM   5765  C CE2 . TYR B 2 564 ? 198.114 125.744 58.742  1.00 273.51 ? 586 TYR B CE2 1 
ATOM   5766  C CZ  . TYR B 2 564 ? 196.746 125.643 58.889  1.00 273.51 ? 586 TYR B CZ  1 
ATOM   5767  O OH  . TYR B 2 564 ? 195.931 125.732 57.784  1.00 273.51 ? 586 TYR B OH  1 
ATOM   5768  N N   . MET B 2 565 ? 199.007 127.450 64.905  1.00 276.51 ? 587 MET B N   1 
ATOM   5769  C CA  . MET B 2 565 ? 198.893 127.556 66.353  1.00 276.51 ? 587 MET B CA  1 
ATOM   5770  C C   . MET B 2 565 ? 197.630 126.836 66.806  1.00 276.51 ? 587 MET B C   1 
ATOM   5771  O O   . MET B 2 565 ? 196.546 127.079 66.265  1.00 276.51 ? 587 MET B O   1 
ATOM   5772  C CB  . MET B 2 565 ? 198.862 129.021 66.795  1.00 276.51 ? 587 MET B CB  1 
ATOM   5773  C CG  . MET B 2 565 ? 198.401 129.233 68.228  1.00 276.51 ? 587 MET B CG  1 
ATOM   5774  S SD  . MET B 2 565 ? 196.685 129.775 68.330  1.00 276.51 ? 587 MET B SD  1 
ATOM   5775  C CE  . MET B 2 565 ? 196.771 131.331 67.447  1.00 276.51 ? 587 MET B CE  1 
ATOM   5776  N N   . VAL B 2 566 ? 197.772 125.957 67.794  1.00 277.43 ? 588 VAL B N   1 
ATOM   5777  C CA  . VAL B 2 566 ? 196.668 125.137 68.275  1.00 277.43 ? 588 VAL B CA  1 
ATOM   5778  C C   . VAL B 2 566 ? 196.297 125.569 69.686  1.00 277.43 ? 588 VAL B C   1 
ATOM   5779  O O   . VAL B 2 566 ? 197.134 126.059 70.453  1.00 277.43 ? 588 VAL B O   1 
ATOM   5780  C CB  . VAL B 2 566 ? 197.015 123.634 68.239  1.00 277.43 ? 588 VAL B CB  1 
ATOM   5781  C CG1 . VAL B 2 566 ? 197.019 123.124 66.807  1.00 277.43 ? 588 VAL B CG1 1 
ATOM   5782  C CG2 . VAL B 2 566 ? 198.359 123.384 68.906  1.00 277.43 ? 588 VAL B CG2 1 
ATOM   5783  N N   . ARG B 2 567 ? 195.023 125.381 70.024  1.00 278.74 ? 589 ARG B N   1 
ATOM   5784  C CA  . ARG B 2 567 ? 194.518 125.673 71.359  1.00 278.74 ? 589 ARG B CA  1 
ATOM   5785  C C   . ARG B 2 567 ? 193.408 124.684 71.681  1.00 278.74 ? 589 ARG B C   1 
ATOM   5786  O O   . ARG B 2 567 ? 192.450 124.556 70.914  1.00 278.74 ? 589 ARG B O   1 
ATOM   5787  C CB  . ARG B 2 567 ? 193.997 127.111 71.458  1.00 278.74 ? 589 ARG B CB  1 
ATOM   5788  C CG  . ARG B 2 567 ? 193.192 127.389 72.719  1.00 278.74 ? 589 ARG B CG  1 
ATOM   5789  C CD  . ARG B 2 567 ? 192.476 128.727 72.640  1.00 278.74 ? 589 ARG B CD  1 
ATOM   5790  N NE  . ARG B 2 567 ? 193.407 129.851 72.653  1.00 278.74 ? 589 ARG B NE  1 
ATOM   5791  C CZ  . ARG B 2 567 ? 193.037 131.127 72.629  1.00 278.74 ? 589 ARG B CZ  1 
ATOM   5792  N NH1 . ARG B 2 567 ? 191.750 131.446 72.589  1.00 278.74 ? 589 ARG B NH1 1 
ATOM   5793  N NH2 . ARG B 2 567 ? 193.953 132.086 72.644  1.00 278.74 ? 589 ARG B NH2 1 
ATOM   5794  N N   . MET B 2 568 ? 193.540 123.993 72.810  1.00 277.01 ? 590 MET B N   1 
ATOM   5795  C CA  . MET B 2 568 ? 192.587 122.975 73.228  1.00 277.01 ? 590 MET B CA  1 
ATOM   5796  C C   . MET B 2 568 ? 191.999 123.355 74.578  1.00 277.01 ? 590 MET B C   1 
ATOM   5797  O O   . MET B 2 568 ? 192.738 123.686 75.511  1.00 277.01 ? 590 MET B O   1 
ATOM   5798  C CB  . MET B 2 568 ? 193.254 121.599 73.305  1.00 277.01 ? 590 MET B CB  1 
ATOM   5799  C CG  . MET B 2 568 ? 192.379 120.513 73.906  1.00 277.01 ? 590 MET B CG  1 
ATOM   5800  S SD  . MET B 2 568 ? 193.253 118.946 74.078  1.00 277.01 ? 590 MET B SD  1 
ATOM   5801  C CE  . MET B 2 568 ? 192.017 117.964 74.921  1.00 277.01 ? 590 MET B CE  1 
ATOM   5802  N N   . ALA B 2 569 ? 190.674 123.304 74.678  1.00 271.08 ? 591 ALA B N   1 
ATOM   5803  C CA  . ALA B 2 569 ? 189.963 123.624 75.904  1.00 271.08 ? 591 ALA B CA  1 
ATOM   5804  C C   . ALA B 2 569 ? 189.092 122.448 76.321  1.00 271.08 ? 591 ALA B C   1 
ATOM   5805  O O   . ALA B 2 569 ? 188.559 121.718 75.479  1.00 271.08 ? 591 ALA B O   1 
ATOM   5806  C CB  . ALA B 2 569 ? 189.098 124.879 75.736  1.00 271.08 ? 591 ALA B CB  1 
ATOM   5807  N N   . ALA B 2 570 ? 188.952 122.271 77.631  1.00 269.87 ? 592 ALA B N   1 
ATOM   5808  C CA  . ALA B 2 570 ? 188.137 121.210 78.208  1.00 269.87 ? 592 ALA B CA  1 
ATOM   5809  C C   . ALA B 2 570 ? 186.888 121.831 78.817  1.00 269.87 ? 592 ALA B C   1 
ATOM   5810  O O   . ALA B 2 570 ? 186.985 122.689 79.701  1.00 269.87 ? 592 ALA B O   1 
ATOM   5811  C CB  . ALA B 2 570 ? 188.920 120.426 79.261  1.00 269.87 ? 592 ALA B CB  1 
ATOM   5812  N N   . TYR B 2 571 ? 185.723 121.396 78.346  1.00 269.09 ? 593 TYR B N   1 
ATOM   5813  C CA  . TYR B 2 571 ? 184.444 121.944 78.776  1.00 269.09 ? 593 TYR B CA  1 
ATOM   5814  C C   . TYR B 2 571 ? 183.744 120.953 79.694  1.00 269.09 ? 593 TYR B C   1 
ATOM   5815  O O   . TYR B 2 571 ? 183.704 119.752 79.407  1.00 269.09 ? 593 TYR B O   1 
ATOM   5816  C CB  . TYR B 2 571 ? 183.559 122.270 77.571  1.00 269.09 ? 593 TYR B CB  1 
ATOM   5817  C CG  . TYR B 2 571 ? 184.018 123.478 76.786  1.00 269.09 ? 593 TYR B CG  1 
ATOM   5818  C CD1 . TYR B 2 571 ? 183.430 124.722 76.981  1.00 269.09 ? 593 TYR B CD1 1 
ATOM   5819  C CD2 . TYR B 2 571 ? 185.040 123.376 75.852  1.00 269.09 ? 593 TYR B CD2 1 
ATOM   5820  C CE1 . TYR B 2 571 ? 183.847 125.829 76.267  1.00 269.09 ? 593 TYR B CE1 1 
ATOM   5821  C CE2 . TYR B 2 571 ? 185.464 124.478 75.133  1.00 269.09 ? 593 TYR B CE2 1 
ATOM   5822  C CZ  . TYR B 2 571 ? 184.864 125.701 75.344  1.00 269.09 ? 593 TYR B CZ  1 
ATOM   5823  O OH  . TYR B 2 571 ? 185.283 126.800 74.630  1.00 269.09 ? 593 TYR B OH  1 
ATOM   5824  N N   . THR B 2 572 ? 183.199 121.460 80.793  1.00 264.46 ? 594 THR B N   1 
ATOM   5825  C CA  . THR B 2 572 ? 182.466 120.669 81.771  1.00 264.46 ? 594 THR B CA  1 
ATOM   5826  C C   . THR B 2 572 ? 181.011 121.147 81.783  1.00 264.46 ? 594 THR B C   1 
ATOM   5827  O O   . THR B 2 572 ? 180.612 122.000 80.985  1.00 264.46 ? 594 THR B O   1 
ATOM   5828  C CB  . THR B 2 572 ? 183.138 120.779 83.145  1.00 264.46 ? 594 THR B CB  1 
ATOM   5829  O OG1 . THR B 2 572 ? 184.559 120.825 82.973  1.00 264.46 ? 594 THR B OG1 1 
ATOM   5830  C CG2 . THR B 2 572 ? 182.808 119.569 84.014  1.00 264.46 ? 594 THR B CG2 1 
ATOM   5831  N N   . ASP B 2 573 ? 180.210 120.587 82.694  1.00 263.86 ? 595 ASP B N   1 
ATOM   5832  C CA  . ASP B 2 573 ? 178.808 120.975 82.792  1.00 263.86 ? 595 ASP B CA  1 
ATOM   5833  C C   . ASP B 2 573 ? 178.632 122.414 83.259  1.00 263.86 ? 595 ASP B C   1 
ATOM   5834  O O   . ASP B 2 573 ? 177.546 122.980 83.090  1.00 263.86 ? 595 ASP B O   1 
ATOM   5835  C CB  . ASP B 2 573 ? 178.066 120.030 83.740  1.00 263.86 ? 595 ASP B CB  1 
ATOM   5836  C CG  . ASP B 2 573 ? 178.156 118.581 83.306  1.00 263.86 ? 595 ASP B CG  1 
ATOM   5837  O OD1 . ASP B 2 573 ? 178.588 118.328 82.162  1.00 263.86 ? 595 ASP B OD1 1 
ATOM   5838  O OD2 . ASP B 2 573 ? 177.796 117.694 84.109  1.00 263.86 ? 595 ASP B OD2 1 
ATOM   5839  N N   . GLU B 2 574 ? 179.666 123.018 83.840  1.00 264.43 ? 596 GLU B N   1 
ATOM   5840  C CA  . GLU B 2 574 ? 179.616 124.391 84.327  1.00 264.43 ? 596 GLU B CA  1 
ATOM   5841  C C   . GLU B 2 574 ? 180.604 125.273 83.573  1.00 264.43 ? 596 GLU B C   1 
ATOM   5842  O O   . GLU B 2 574 ? 181.300 126.105 84.160  1.00 264.43 ? 596 GLU B O   1 
ATOM   5843  C CB  . GLU B 2 574 ? 179.881 124.443 85.831  1.00 264.43 ? 596 GLU B CB  1 
ATOM   5844  C CG  . GLU B 2 574 ? 179.215 125.613 86.542  1.00 264.43 ? 596 GLU B CG  1 
ATOM   5845  C CD  . GLU B 2 574 ? 177.710 125.458 86.642  1.00 264.43 ? 596 GLU B CD  1 
ATOM   5846  O OE1 . GLU B 2 574 ? 177.223 124.309 86.584  1.00 264.43 ? 596 GLU B OE1 1 
ATOM   5847  O OE2 . GLU B 2 574 ? 177.014 126.486 86.778  1.00 264.43 ? 596 GLU B OE2 1 
ATOM   5848  N N   . GLY B 2 575 ? 180.678 125.098 82.261  1.00 264.93 ? 597 GLY B N   1 
ATOM   5849  C CA  . GLY B 2 575 ? 181.560 125.890 81.431  1.00 264.93 ? 597 GLY B CA  1 
ATOM   5850  C C   . GLY B 2 575 ? 182.812 125.142 81.018  1.00 264.93 ? 597 GLY B C   1 
ATOM   5851  O O   . GLY B 2 575 ? 182.893 123.912 81.060  1.00 264.93 ? 597 GLY B O   1 
ATOM   5852  N N   . GLY B 2 576 ? 183.813 125.920 80.610  1.00 264.08 ? 598 GLY B N   1 
ATOM   5853  C CA  . GLY B 2 576 ? 185.078 125.371 80.172  1.00 264.08 ? 598 GLY B CA  1 
ATOM   5854  C C   . GLY B 2 576 ? 186.214 126.319 80.489  1.00 264.08 ? 598 GLY B C   1 
ATOM   5855  O O   . GLY B 2 576 ? 186.009 127.422 81.001  1.00 264.08 ? 598 GLY B O   1 
ATOM   5856  N N   . LYS B 2 577 ? 187.429 125.874 80.175  1.00 257.89 ? 599 LYS B N   1 
ATOM   5857  C CA  . LYS B 2 577 ? 188.633 126.655 80.423  1.00 257.89 ? 599 LYS B CA  1 
ATOM   5858  C C   . LYS B 2 577 ? 189.629 126.404 79.303  1.00 257.89 ? 599 LYS B C   1 
ATOM   5859  O O   . LYS B 2 577 ? 189.921 125.250 78.976  1.00 257.89 ? 599 LYS B O   1 
ATOM   5860  C CB  . LYS B 2 577 ? 189.258 126.298 81.776  1.00 257.89 ? 599 LYS B CB  1 
ATOM   5861  C CG  . LYS B 2 577 ? 190.330 127.270 82.239  1.00 257.89 ? 599 LYS B CG  1 
ATOM   5862  C CD  . LYS B 2 577 ? 189.738 128.636 82.546  1.00 257.89 ? 599 LYS B CD  1 
ATOM   5863  C CE  . LYS B 2 577 ? 188.698 128.551 83.651  1.00 257.89 ? 599 LYS B CE  1 
ATOM   5864  N NZ  . LYS B 2 577 ? 188.100 129.880 83.954  1.00 257.89 ? 599 LYS B NZ  1 
ATOM   5865  N N   . ASP B 2 578 ? 190.146 127.482 78.720  1.00 256.72 ? 600 ASP B N   1 
ATOM   5866  C CA  . ASP B 2 578 ? 191.113 127.358 77.641  1.00 256.72 ? 600 ASP B CA  1 
ATOM   5867  C C   . ASP B 2 578 ? 192.454 126.865 78.173  1.00 256.72 ? 600 ASP B C   1 
ATOM   5868  O O   . ASP B 2 578 ? 192.807 127.080 79.336  1.00 256.72 ? 600 ASP B O   1 
ATOM   5869  C CB  . ASP B 2 578 ? 191.292 128.698 76.928  1.00 256.72 ? 600 ASP B CB  1 
ATOM   5870  C CG  . ASP B 2 578 ? 190.027 129.161 76.233  1.00 256.72 ? 600 ASP B CG  1 
ATOM   5871  O OD1 . ASP B 2 578 ? 189.015 128.431 76.289  1.00 256.72 ? 600 ASP B OD1 1 
ATOM   5872  O OD2 . ASP B 2 578 ? 190.044 130.255 75.631  1.00 256.72 ? 600 ASP B OD2 1 
ATOM   5873  N N   . GLY B 2 579 ? 193.204 126.194 77.304  1.00 260.08 ? 601 GLY B N   1 
ATOM   5874  C CA  . GLY B 2 579 ? 194.496 125.662 77.663  1.00 260.08 ? 601 GLY B CA  1 
ATOM   5875  C C   . GLY B 2 579 ? 195.635 126.493 77.111  1.00 260.08 ? 601 GLY B C   1 
ATOM   5876  O O   . GLY B 2 579 ? 195.429 127.539 76.487  1.00 260.08 ? 601 GLY B O   1 
ATOM   5877  N N   . PRO B 2 580 ? 196.866 126.041 77.336  1.00 263.05 ? 602 PRO B N   1 
ATOM   5878  C CA  . PRO B 2 580 ? 198.027 126.778 76.827  1.00 263.05 ? 602 PRO B CA  1 
ATOM   5879  C C   . PRO B 2 580 ? 198.138 126.672 75.314  1.00 263.05 ? 602 PRO B C   1 
ATOM   5880  O O   . PRO B 2 580 ? 197.593 125.767 74.679  1.00 263.05 ? 602 PRO B O   1 
ATOM   5881  C CB  . PRO B 2 580 ? 199.212 126.101 77.521  1.00 263.05 ? 602 PRO B CB  1 
ATOM   5882  C CG  . PRO B 2 580 ? 198.728 124.724 77.829  1.00 263.05 ? 602 PRO B CG  1 
ATOM   5883  C CD  . PRO B 2 580 ? 197.255 124.843 78.099  1.00 263.05 ? 602 PRO B CD  1 
ATOM   5884  N N   . GLU B 2 581 ? 198.862 127.626 74.739  1.00 268.97 ? 603 GLU B N   1 
ATOM   5885  C CA  . GLU B 2 581 ? 199.042 127.698 73.297  1.00 268.97 ? 603 GLU B CA  1 
ATOM   5886  C C   . GLU B 2 581 ? 200.295 126.944 72.869  1.00 268.97 ? 603 GLU B C   1 
ATOM   5887  O O   . GLU B 2 581 ? 201.295 126.897 73.590  1.00 268.97 ? 603 GLU B O   1 
ATOM   5888  C CB  . GLU B 2 581 ? 199.130 129.154 72.836  1.00 268.97 ? 603 GLU B CB  1 
ATOM   5889  C CG  . GLU B 2 581 ? 197.917 129.999 73.192  1.00 268.97 ? 603 GLU B CG  1 
ATOM   5890  C CD  . GLU B 2 581 ? 196.828 129.937 72.137  1.00 268.97 ? 603 GLU B CD  1 
ATOM   5891  O OE1 . GLU B 2 581 ? 196.743 128.916 71.423  1.00 268.97 ? 603 GLU B OE1 1 
ATOM   5892  O OE2 . GLU B 2 581 ? 196.058 130.913 72.020  1.00 268.97 ? 603 GLU B OE2 1 
ATOM   5893  N N   . PHE B 2 582 ? 200.227 126.351 71.679  1.00 269.66 ? 604 PHE B N   1 
ATOM   5894  C CA  . PHE B 2 582 ? 201.351 125.633 71.098  1.00 269.66 ? 604 PHE B CA  1 
ATOM   5895  C C   . PHE B 2 582 ? 201.400 125.907 69.602  1.00 269.66 ? 604 PHE B C   1 
ATOM   5896  O O   . PHE B 2 582 ? 200.365 126.092 68.956  1.00 269.66 ? 604 PHE B O   1 
ATOM   5897  C CB  . PHE B 2 582 ? 201.262 124.120 71.351  1.00 269.66 ? 604 PHE B CB  1 
ATOM   5898  C CG  . PHE B 2 582 ? 201.107 123.754 72.800  1.00 269.66 ? 604 PHE B CG  1 
ATOM   5899  C CD1 . PHE B 2 582 ? 202.219 123.489 73.582  1.00 269.66 ? 604 PHE B CD1 1 
ATOM   5900  C CD2 . PHE B 2 582 ? 199.852 123.662 73.378  1.00 269.66 ? 604 PHE B CD2 1 
ATOM   5901  C CE1 . PHE B 2 582 ? 202.083 123.149 74.915  1.00 269.66 ? 604 PHE B CE1 1 
ATOM   5902  C CE2 . PHE B 2 582 ? 199.709 123.323 74.710  1.00 269.66 ? 604 PHE B CE2 1 
ATOM   5903  C CZ  . PHE B 2 582 ? 200.826 123.065 75.479  1.00 269.66 ? 604 PHE B CZ  1 
ATOM   5904  N N   . THR B 2 583 ? 202.615 125.932 69.060  1.00 273.56 ? 605 THR B N   1 
ATOM   5905  C CA  . THR B 2 583 ? 202.839 126.194 67.644  1.00 273.56 ? 605 THR B CA  1 
ATOM   5906  C C   . THR B 2 583 ? 203.807 125.159 67.094  1.00 273.56 ? 605 THR B C   1 
ATOM   5907  O O   . THR B 2 583 ? 204.879 124.940 67.667  1.00 273.56 ? 605 THR B O   1 
ATOM   5908  C CB  . THR B 2 583 ? 203.389 127.608 67.419  1.00 273.56 ? 605 THR B CB  1 
ATOM   5909  O OG1 . THR B 2 583 ? 202.439 128.573 67.889  1.00 273.56 ? 605 THR B OG1 1 
ATOM   5910  C CG2 . THR B 2 583 ? 203.656 127.848 65.941  1.00 273.56 ? 605 THR B CG2 1 
ATOM   5911  N N   . PHE B 2 584 ? 203.428 124.526 65.987  1.00 275.92 ? 606 PHE B N   1 
ATOM   5912  C CA  . PHE B 2 584 ? 204.242 123.506 65.344  1.00 275.92 ? 606 PHE B CA  1 
ATOM   5913  C C   . PHE B 2 584 ? 204.497 123.885 63.891  1.00 275.92 ? 606 PHE B C   1 
ATOM   5914  O O   . PHE B 2 584 ? 203.699 124.590 63.265  1.00 275.92 ? 606 PHE B O   1 
ATOM   5915  C CB  . PHE B 2 584 ? 203.569 122.126 65.417  1.00 275.92 ? 606 PHE B CB  1 
ATOM   5916  C CG  . PHE B 2 584 ? 202.251 122.051 64.698  1.00 275.92 ? 606 PHE B CG  1 
ATOM   5917  C CD1 . PHE B 2 584 ? 201.088 122.498 65.304  1.00 275.92 ? 606 PHE B CD1 1 
ATOM   5918  C CD2 . PHE B 2 584 ? 202.172 121.523 63.419  1.00 275.92 ? 606 PHE B CD2 1 
ATOM   5919  C CE1 . PHE B 2 584 ? 199.874 122.428 64.646  1.00 275.92 ? 606 PHE B CE1 1 
ATOM   5920  C CE2 . PHE B 2 584 ? 200.961 121.450 62.757  1.00 275.92 ? 606 PHE B CE2 1 
ATOM   5921  C CZ  . PHE B 2 584 ? 199.811 121.903 63.371  1.00 275.92 ? 606 PHE B CZ  1 
ATOM   5922  N N   . THR B 2 585 ? 205.620 123.409 63.361  1.00 280.27 ? 607 THR B N   1 
ATOM   5923  C CA  . THR B 2 585 ? 206.032 123.699 61.994  1.00 280.27 ? 607 THR B CA  1 
ATOM   5924  C C   . THR B 2 585 ? 205.711 122.511 61.099  1.00 280.27 ? 607 THR B C   1 
ATOM   5925  O O   . THR B 2 585 ? 205.990 121.362 61.459  1.00 280.27 ? 607 THR B O   1 
ATOM   5926  C CB  . THR B 2 585 ? 207.526 124.018 61.929  1.00 280.27 ? 607 THR B CB  1 
ATOM   5927  O OG1 . THR B 2 585 ? 208.282 122.822 62.158  1.00 280.27 ? 607 THR B OG1 1 
ATOM   5928  C CG2 . THR B 2 585 ? 207.897 125.053 62.980  1.00 280.27 ? 607 THR B CG2 1 
ATOM   5929  N N   . THR B 2 586 ? 205.126 122.790 59.934  1.00 282.40 ? 608 THR B N   1 
ATOM   5930  C CA  . THR B 2 586 ? 204.789 121.749 58.976  1.00 282.40 ? 608 THR B CA  1 
ATOM   5931  C C   . THR B 2 586 ? 205.804 121.763 57.844  1.00 282.40 ? 608 THR B C   1 
ATOM   5932  O O   . THR B 2 586 ? 205.743 122.654 56.984  1.00 282.40 ? 608 THR B O   1 
ATOM   5933  C CB  . THR B 2 586 ? 203.379 121.955 58.426  1.00 282.40 ? 608 THR B CB  1 
ATOM   5934  O OG1 . THR B 2 586 ? 203.363 123.099 57.564  1.00 282.40 ? 608 THR B OG1 1 
ATOM   5935  C CG2 . THR B 2 586 ? 202.393 122.172 59.563  1.00 282.40 ? 608 THR B CG2 1 
ATOM   5936  N N   . PRO B 2 587 ? 206.749 120.812 57.794  1.00 279.67 ? 609 PRO B N   1 
ATOM   5937  C CA  . PRO B 2 587 ? 207.758 120.760 56.731  1.00 279.67 ? 609 PRO B CA  1 
ATOM   5938  C C   . PRO B 2 587 ? 207.181 120.297 55.397  1.00 279.67 ? 609 PRO B C   1 
ATOM   5939  O O   . PRO B 2 587 ? 206.063 119.780 55.376  1.00 279.67 ? 609 PRO B O   1 
ATOM   5940  C CB  . PRO B 2 587 ? 208.773 119.748 57.266  1.00 279.67 ? 609 PRO B CB  1 
ATOM   5941  C CG  . PRO B 2 587 ? 207.971 118.853 58.141  1.00 279.67 ? 609 PRO B CG  1 
ATOM   5942  C CD  . PRO B 2 587 ? 206.919 119.723 58.772  1.00 279.67 ? 609 PRO B CD  1 
ATOM   5943  N N   . PRO C 3 6   ? 170.199 174.029 234.734 1.00 205.46 ? 29  PRO C N   1 
ATOM   5944  C CA  . PRO C 3 6   ? 170.198 174.063 233.268 1.00 205.46 ? 29  PRO C CA  1 
ATOM   5945  C C   . PRO C 3 6   ? 168.812 174.326 232.689 1.00 205.46 ? 29  PRO C C   1 
ATOM   5946  O O   . PRO C 3 6   ? 167.809 173.964 233.305 1.00 205.46 ? 29  PRO C O   1 
ATOM   5947  C CB  . PRO C 3 6   ? 170.691 172.665 232.887 1.00 205.46 ? 29  PRO C CB  1 
ATOM   5948  C CG  . PRO C 3 6   ? 170.287 171.806 234.033 1.00 205.46 ? 29  PRO C CG  1 
ATOM   5949  C CD  . PRO C 3 6   ? 170.417 172.669 235.256 1.00 205.46 ? 29  PRO C CD  1 
ATOM   5950  N N   . LEU C 3 7   ? 168.763 174.949 231.518 1.00 198.17 ? 30  LEU C N   1 
ATOM   5951  C CA  . LEU C 3 7   ? 167.490 175.249 230.874 1.00 198.17 ? 30  LEU C CA  1 
ATOM   5952  C C   . LEU C 3 7   ? 166.931 173.988 230.226 1.00 198.17 ? 30  LEU C C   1 
ATOM   5953  O O   . LEU C 3 7   ? 167.556 173.449 229.305 1.00 198.17 ? 30  LEU C O   1 
ATOM   5954  C CB  . LEU C 3 7   ? 167.667 176.344 229.830 1.00 198.17 ? 30  LEU C CB  1 
ATOM   5955  C CG  . LEU C 3 7   ? 166.439 176.728 229.003 1.00 198.17 ? 30  LEU C CG  1 
ATOM   5956  C CD1 . LEU C 3 7   ? 165.285 177.138 229.905 1.00 198.17 ? 30  LEU C CD1 1 
ATOM   5957  C CD2 . LEU C 3 7   ? 166.781 177.843 228.026 1.00 198.17 ? 30  LEU C CD2 1 
ATOM   5958  N N   . PRO C 3 8   ? 165.775 173.486 230.667 1.00 191.34 ? 31  PRO C N   1 
ATOM   5959  C CA  . PRO C 3 8   ? 165.231 172.258 230.072 1.00 191.34 ? 31  PRO C CA  1 
ATOM   5960  C C   . PRO C 3 8   ? 164.647 172.488 228.687 1.00 191.34 ? 31  PRO C C   1 
ATOM   5961  O O   . PRO C 3 8   ? 163.427 172.587 228.528 1.00 191.34 ? 31  PRO C O   1 
ATOM   5962  C CB  . PRO C 3 8   ? 164.152 171.834 231.075 1.00 191.34 ? 31  PRO C CB  1 
ATOM   5963  C CG  . PRO C 3 8   ? 163.718 173.111 231.712 1.00 191.34 ? 31  PRO C CG  1 
ATOM   5964  C CD  . PRO C 3 8   ? 164.938 173.992 231.768 1.00 191.34 ? 31  PRO C CD  1 
ATOM   5965  N N   . LEU C 3 9   ? 165.513 172.569 227.676 1.00 179.24 ? 32  LEU C N   1 
ATOM   5966  C CA  . LEU C 3 9   ? 165.080 172.760 226.291 1.00 179.24 ? 32  LEU C CA  1 
ATOM   5967  C C   . LEU C 3 9   ? 164.599 171.422 225.725 1.00 179.24 ? 32  LEU C C   1 
ATOM   5968  O O   . LEU C 3 9   ? 165.242 170.784 224.890 1.00 179.24 ? 32  LEU C O   1 
ATOM   5969  C CB  . LEU C 3 9   ? 166.207 173.351 225.456 1.00 179.24 ? 32  LEU C CB  1 
ATOM   5970  C CG  . LEU C 3 9   ? 166.545 174.821 225.709 1.00 179.24 ? 32  LEU C CG  1 
ATOM   5971  C CD1 . LEU C 3 9   ? 167.791 175.225 224.937 1.00 179.24 ? 32  LEU C CD1 1 
ATOM   5972  C CD2 . LEU C 3 9   ? 165.369 175.710 225.338 1.00 179.24 ? 32  LEU C CD2 1 
ATOM   5973  N N   . THR C 3 10  ? 163.429 171.001 226.205 1.00 158.33 ? 33  THR C N   1 
ATOM   5974  C CA  . THR C 3 10  ? 162.840 169.739 225.786 1.00 158.33 ? 33  THR C CA  1 
ATOM   5975  C C   . THR C 3 10  ? 161.845 169.997 224.666 1.00 158.33 ? 33  THR C C   1 
ATOM   5976  O O   . THR C 3 10  ? 160.812 170.640 224.907 1.00 158.33 ? 33  THR C O   1 
ATOM   5977  C CB  . THR C 3 10  ? 162.152 169.048 226.961 1.00 158.33 ? 33  THR C CB  1 
ATOM   5978  O OG1 . THR C 3 10  ? 161.043 169.842 227.401 1.00 158.33 ? 33  THR C OG1 1 
ATOM   5979  C CG2 . THR C 3 10  ? 163.127 168.865 228.115 1.00 158.33 ? 33  THR C CG2 1 
ATOM   5980  N N   . PRO C 3 11  ? 162.102 169.533 223.446 1.00 136.74 ? 34  PRO C N   1 
ATOM   5981  C CA  . PRO C 3 11  ? 161.145 169.758 222.357 1.00 136.74 ? 34  PRO C CA  1 
ATOM   5982  C C   . PRO C 3 11  ? 159.849 168.998 222.584 1.00 136.74 ? 34  PRO C C   1 
ATOM   5983  O O   . PRO C 3 11  ? 159.828 167.909 223.163 1.00 136.74 ? 34  PRO C O   1 
ATOM   5984  C CB  . PRO C 3 11  ? 161.884 169.236 221.118 1.00 136.74 ? 34  PRO C CB  1 
ATOM   5985  C CG  . PRO C 3 11  ? 163.329 169.181 221.517 1.00 136.74 ? 34  PRO C CG  1 
ATOM   5986  C CD  . PRO C 3 11  ? 163.327 168.868 222.977 1.00 136.74 ? 34  PRO C CD  1 
ATOM   5987  N N   . GLU C 3 12  ? 158.755 169.592 222.114 1.00 125.76 ? 35  GLU C N   1 
ATOM   5988  C CA  . GLU C 3 12  ? 157.421 169.018 222.243 1.00 125.76 ? 35  GLU C CA  1 
ATOM   5989  C C   . GLU C 3 12  ? 156.829 168.838 220.853 1.00 125.76 ? 35  GLU C C   1 
ATOM   5990  O O   . GLU C 3 12  ? 156.656 169.817 220.118 1.00 125.76 ? 35  GLU C O   1 
ATOM   5991  C CB  . GLU C 3 12  ? 156.521 169.907 223.104 1.00 125.76 ? 35  GLU C CB  1 
ATOM   5992  C CG  . GLU C 3 12  ? 155.051 169.525 223.066 1.00 125.76 ? 35  GLU C CG  1 
ATOM   5993  C CD  . GLU C 3 12  ? 154.213 170.352 224.021 1.00 125.76 ? 35  GLU C CD  1 
ATOM   5994  O OE1 . GLU C 3 12  ? 154.583 170.447 225.210 1.00 125.76 ? 35  GLU C OE1 1 
ATOM   5995  O OE2 . GLU C 3 12  ? 153.184 170.907 223.582 1.00 125.76 ? 35  GLU C OE2 1 
ATOM   5996  N N   . ILE C 3 13  ? 156.522 167.595 220.498 1.00 107.40 ? 36  ILE C N   1 
ATOM   5997  C CA  . ILE C 3 13  ? 155.959 167.287 219.187 1.00 107.40 ? 36  ILE C CA  1 
ATOM   5998  C C   . ILE C 3 13  ? 154.484 167.670 219.183 1.00 107.40 ? 36  ILE C C   1 
ATOM   5999  O O   . ILE C 3 13  ? 153.712 167.220 220.037 1.00 107.40 ? 36  ILE C O   1 
ATOM   6000  C CB  . ILE C 3 13  ? 156.149 165.804 218.840 1.00 107.40 ? 36  ILE C CB  1 
ATOM   6001  C CG1 . ILE C 3 13  ? 157.612 165.529 218.479 1.00 107.40 ? 36  ILE C CG1 1 
ATOM   6002  C CG2 . ILE C 3 13  ? 155.222 165.396 217.705 1.00 107.40 ? 36  ILE C CG2 1 
ATOM   6003  C CD1 . ILE C 3 13  ? 157.890 164.097 218.086 1.00 107.40 ? 36  ILE C CD1 1 
ATOM   6004  N N   . HIS C 3 14  ? 154.091 168.504 218.221 1.00 110.22 ? 37  HIS C N   1 
ATOM   6005  C CA  . HIS C 3 14  ? 152.715 168.981 218.129 1.00 110.22 ? 37  HIS C CA  1 
ATOM   6006  C C   . HIS C 3 14  ? 151.876 168.116 217.191 1.00 110.22 ? 37  HIS C C   1 
ATOM   6007  O O   . HIS C 3 14  ? 150.867 167.537 217.605 1.00 110.22 ? 37  HIS C O   1 
ATOM   6008  C CB  . HIS C 3 14  ? 152.695 170.442 217.667 1.00 110.22 ? 37  HIS C CB  1 
ATOM   6009  C CG  . HIS C 3 14  ? 153.302 171.396 218.649 1.00 110.22 ? 37  HIS C CG  1 
ATOM   6010  N ND1 . HIS C 3 14  ? 152.553 172.078 219.584 1.00 110.22 ? 37  HIS C ND1 1 
ATOM   6011  C CD2 . HIS C 3 14  ? 154.585 171.782 218.839 1.00 110.22 ? 37  HIS C CD2 1 
ATOM   6012  C CE1 . HIS C 3 14  ? 153.350 172.843 220.309 1.00 110.22 ? 37  HIS C CE1 1 
ATOM   6013  N NE2 . HIS C 3 14  ? 154.588 172.682 219.878 1.00 110.22 ? 37  HIS C NE2 1 
ATOM   6014  N N   . LYS C 3 15  ? 152.282 168.022 215.927 1.00 95.05  ? 38  LYS C N   1 
ATOM   6015  C CA  . LYS C 3 15  ? 151.509 167.315 214.916 1.00 95.05  ? 38  LYS C CA  1 
ATOM   6016  C C   . LYS C 3 15  ? 152.438 166.477 214.052 1.00 95.05  ? 38  LYS C C   1 
ATOM   6017  O O   . LYS C 3 15  ? 153.526 166.925 213.681 1.00 95.05  ? 38  LYS C O   1 
ATOM   6018  C CB  . LYS C 3 15  ? 150.718 168.294 214.038 1.00 95.05  ? 38  LYS C CB  1 
ATOM   6019  C CG  . LYS C 3 15  ? 149.970 167.641 212.888 1.00 95.05  ? 38  LYS C CG  1 
ATOM   6020  C CD  . LYS C 3 15  ? 149.389 168.680 211.944 1.00 95.05  ? 38  LYS C CD  1 
ATOM   6021  C CE  . LYS C 3 15  ? 148.748 168.025 210.732 1.00 95.05  ? 38  LYS C CE  1 
ATOM   6022  N NZ  . LYS C 3 15  ? 148.212 169.031 209.775 1.00 95.05  ? 38  LYS C NZ  1 
ATOM   6023  N N   . VAL C 3 16  ? 152.000 165.260 213.736 1.00 74.94  ? 39  VAL C N   1 
ATOM   6024  C CA  . VAL C 3 16  ? 152.727 164.354 212.857 1.00 74.94  ? 39  VAL C CA  1 
ATOM   6025  C C   . VAL C 3 16  ? 151.812 163.960 211.706 1.00 74.94  ? 39  VAL C C   1 
ATOM   6026  O O   . VAL C 3 16  ? 150.616 163.718 211.905 1.00 74.94  ? 39  VAL C O   1 
ATOM   6027  C CB  . VAL C 3 16  ? 153.238 163.111 213.619 1.00 74.94  ? 39  VAL C CB  1 
ATOM   6028  C CG1 . VAL C 3 16  ? 152.087 162.374 214.292 1.00 74.94  ? 39  VAL C CG1 1 
ATOM   6029  C CG2 . VAL C 3 16  ? 154.005 162.184 212.687 1.00 74.94  ? 39  VAL C CG2 1 
ATOM   6030  N N   . SER C 3 17  ? 152.370 163.919 210.499 1.00 73.56  ? 40  SER C N   1 
ATOM   6031  C CA  . SER C 3 17  ? 151.627 163.564 209.300 1.00 73.56  ? 40  SER C CA  1 
ATOM   6032  C C   . SER C 3 17  ? 152.406 162.519 208.513 1.00 73.56  ? 40  SER C C   1 
ATOM   6033  O O   . SER C 3 17  ? 153.573 162.235 208.796 1.00 73.56  ? 40  SER C O   1 
ATOM   6034  C CB  . SER C 3 17  ? 151.351 164.794 208.426 1.00 73.56  ? 40  SER C CB  1 
ATOM   6035  O OG  . SER C 3 17  ? 151.095 164.416 207.084 1.00 73.56  ? 40  SER C OG  1 
ATOM   6036  N N   . PHE C 3 18  ? 151.745 161.943 207.512 1.00 69.01  ? 41  PHE C N   1 
ATOM   6037  C CA  . PHE C 3 18  ? 152.343 160.920 206.670 1.00 69.01  ? 41  PHE C CA  1 
ATOM   6038  C C   . PHE C 3 18  ? 152.063 161.225 205.206 1.00 69.01  ? 41  PHE C C   1 
ATOM   6039  O O   . PHE C 3 18  ? 151.187 162.026 204.871 1.00 69.01  ? 41  PHE C O   1 
ATOM   6040  C CB  . PHE C 3 18  ? 151.817 159.520 207.018 1.00 69.01  ? 41  PHE C CB  1 
ATOM   6041  C CG  . PHE C 3 18  ? 151.571 159.311 208.482 1.00 69.01  ? 41  PHE C CG  1 
ATOM   6042  C CD1 . PHE C 3 18  ? 152.630 159.190 209.365 1.00 69.01  ? 41  PHE C CD1 1 
ATOM   6043  C CD2 . PHE C 3 18  ? 150.281 159.232 208.977 1.00 69.01  ? 41  PHE C CD2 1 
ATOM   6044  C CE1 . PHE C 3 18  ? 152.406 158.998 210.714 1.00 69.01  ? 41  PHE C CE1 1 
ATOM   6045  C CE2 . PHE C 3 18  ? 150.051 159.039 210.325 1.00 69.01  ? 41  PHE C CE2 1 
ATOM   6046  C CZ  . PHE C 3 18  ? 151.116 158.921 211.195 1.00 69.01  ? 41  PHE C CZ  1 
ATOM   6047  N N   . GLN C 3 19  ? 152.828 160.569 204.334 1.00 67.92  ? 42  GLN C N   1 
ATOM   6048  C CA  . GLN C 3 19  ? 152.637 160.689 202.890 1.00 67.92  ? 42  GLN C CA  1 
ATOM   6049  C C   . GLN C 3 19  ? 153.004 159.339 202.280 1.00 67.92  ? 42  GLN C C   1 
ATOM   6050  O O   . GLN C 3 19  ? 154.181 159.069 202.025 1.00 67.92  ? 42  GLN C O   1 
ATOM   6051  C CB  . GLN C 3 19  ? 153.479 161.817 202.311 1.00 67.92  ? 42  GLN C CB  1 
ATOM   6052  C CG  . GLN C 3 19  ? 153.202 162.107 200.847 1.00 67.92  ? 42  GLN C CG  1 
ATOM   6053  C CD  . GLN C 3 19  ? 153.929 163.341 200.352 1.00 67.92  ? 42  GLN C CD  1 
ATOM   6054  O OE1 . GLN C 3 19  ? 154.629 164.009 201.112 1.00 67.92  ? 42  GLN C OE1 1 
ATOM   6055  N NE2 . GLN C 3 19  ? 153.765 163.651 199.071 1.00 67.92  ? 42  GLN C NE2 1 
ATOM   6056  N N   . LEU C 3 20  ? 151.991 158.500 202.051 1.00 66.22  ? 43  LEU C N   1 
ATOM   6057  C CA  . LEU C 3 20  ? 152.236 157.134 201.606 1.00 66.22  ? 43  LEU C CA  1 
ATOM   6058  C C   . LEU C 3 20  ? 152.736 157.061 200.170 1.00 66.22  ? 43  LEU C C   1 
ATOM   6059  O O   . LEU C 3 20  ? 153.307 156.038 199.780 1.00 66.22  ? 43  LEU C O   1 
ATOM   6060  C CB  . LEU C 3 20  ? 150.962 156.301 201.754 1.00 66.22  ? 43  LEU C CB  1 
ATOM   6061  C CG  . LEU C 3 20  ? 150.295 156.330 203.131 1.00 66.22  ? 43  LEU C CG  1 
ATOM   6062  C CD1 . LEU C 3 20  ? 149.105 155.384 203.172 1.00 66.22  ? 43  LEU C CD1 1 
ATOM   6063  C CD2 . LEU C 3 20  ? 151.296 155.986 204.223 1.00 66.22  ? 43  LEU C CD2 1 
ATOM   6064  N N   . LYS C 3 21  ? 152.538 158.115 199.376 1.00 67.00  ? 44  LYS C N   1 
ATOM   6065  C CA  . LYS C 3 21  ? 152.977 158.074 197.984 1.00 67.00  ? 44  LYS C CA  1 
ATOM   6066  C C   . LYS C 3 21  ? 154.493 158.184 197.877 1.00 67.00  ? 44  LYS C C   1 
ATOM   6067  O O   . LYS C 3 21  ? 155.111 157.515 197.040 1.00 67.00  ? 44  LYS C O   1 
ATOM   6068  C CB  . LYS C 3 21  ? 152.299 159.188 197.187 1.00 67.00  ? 44  LYS C CB  1 
ATOM   6069  C CG  . LYS C 3 21  ? 152.669 159.210 195.713 1.00 67.00  ? 44  LYS C CG  1 
ATOM   6070  C CD  . LYS C 3 21  ? 152.287 157.909 195.026 1.00 67.00  ? 44  LYS C CD  1 
ATOM   6071  C CE  . LYS C 3 21  ? 150.779 157.727 194.985 1.00 67.00  ? 44  LYS C CE  1 
ATOM   6072  N NZ  . LYS C 3 21  ? 150.110 158.814 194.220 1.00 67.00  ? 44  LYS C NZ  1 
ATOM   6073  N N   . LEU C 3 22  ? 155.109 159.017 198.713 1.00 67.03  ? 45  LEU C N   1 
ATOM   6074  C CA  . LEU C 3 22  ? 156.549 159.231 198.683 1.00 67.03  ? 45  LEU C CA  1 
ATOM   6075  C C   . LEU C 3 22  ? 157.273 158.591 199.858 1.00 67.03  ? 45  LEU C C   1 
ATOM   6076  O O   . LEU C 3 22  ? 158.500 158.714 199.949 1.00 67.03  ? 45  LEU C O   1 
ATOM   6077  C CB  . LEU C 3 22  ? 156.859 160.732 198.647 1.00 67.03  ? 45  LEU C CB  1 
ATOM   6078  C CG  . LEU C 3 22  ? 157.015 161.383 197.271 1.00 67.03  ? 45  LEU C CG  1 
ATOM   6079  C CD1 . LEU C 3 22  ? 155.693 161.401 196.518 1.00 67.03  ? 45  LEU C CD1 1 
ATOM   6080  C CD2 . LEU C 3 22  ? 157.574 162.790 197.410 1.00 67.03  ? 45  LEU C CD2 1 
ATOM   6081  N N   . GLN C 3 23  ? 156.552 157.914 200.754 1.00 68.98  ? 46  GLN C N   1 
ATOM   6082  C CA  . GLN C 3 23  ? 157.129 157.287 201.943 1.00 68.98  ? 46  GLN C CA  1 
ATOM   6083  C C   . GLN C 3 23  ? 157.901 158.311 202.779 1.00 68.98  ? 46  GLN C C   1 
ATOM   6084  O O   . GLN C 3 23  ? 159.098 158.174 203.040 1.00 68.98  ? 46  GLN C O   1 
ATOM   6085  C CB  . GLN C 3 23  ? 158.019 156.098 201.562 1.00 68.98  ? 46  GLN C CB  1 
ATOM   6086  C CG  . GLN C 3 23  ? 157.386 155.138 200.569 1.00 68.98  ? 46  GLN C CG  1 
ATOM   6087  C CD  . GLN C 3 23  ? 156.281 154.302 201.183 1.00 68.98  ? 46  GLN C CD  1 
ATOM   6088  O OE1 . GLN C 3 23  ? 156.148 154.227 202.405 1.00 68.98  ? 46  GLN C OE1 1 
ATOM   6089  N NE2 . GLN C 3 23  ? 155.479 153.667 200.336 1.00 68.98  ? 46  GLN C NE2 1 
ATOM   6090  N N   . GLU C 3 24  ? 157.185 159.351 203.198 1.00 68.90  ? 47  GLU C N   1 
ATOM   6091  C CA  . GLU C 3 24  ? 157.761 160.432 203.982 1.00 68.90  ? 47  GLU C CA  1 
ATOM   6092  C C   . GLU C 3 24  ? 156.940 160.642 205.245 1.00 68.90  ? 47  GLU C C   1 
ATOM   6093  O O   . GLU C 3 24  ? 155.730 160.405 205.266 1.00 68.90  ? 47  GLU C O   1 
ATOM   6094  C CB  . GLU C 3 24  ? 157.827 161.739 203.176 1.00 68.90  ? 47  GLU C CB  1 
ATOM   6095  C CG  . GLU C 3 24  ? 158.926 162.701 203.614 1.00 68.90  ? 47  GLU C CG  1 
ATOM   6096  C CD  . GLU C 3 24  ? 160.327 162.199 203.298 1.00 68.90  ? 47  GLU C CD  1 
ATOM   6097  O OE1 . GLU C 3 24  ? 160.464 161.135 202.658 1.00 68.90  ? 47  GLU C OE1 1 
ATOM   6098  O OE2 . GLU C 3 24  ? 161.299 162.876 203.696 1.00 68.90  ? 47  GLU C OE2 1 
ATOM   6099  N N   . VAL C 3 25  ? 157.614 161.090 206.300 1.00 64.57  ? 48  VAL C N   1 
ATOM   6100  C CA  . VAL C 3 25  ? 156.991 161.339 207.597 1.00 64.57  ? 48  VAL C CA  1 
ATOM   6101  C C   . VAL C 3 25  ? 157.274 162.792 207.955 1.00 64.57  ? 48  VAL C C   1 
ATOM   6102  O O   . VAL C 3 25  ? 158.385 163.133 208.377 1.00 64.57  ? 48  VAL C O   1 
ATOM   6103  C CB  . VAL C 3 25  ? 157.507 160.388 208.681 1.00 64.57  ? 48  VAL C CB  1 
ATOM   6104  C CG1 . VAL C 3 25  ? 156.858 160.709 210.018 1.00 64.57  ? 48  VAL C CG1 1 
ATOM   6105  C CG2 . VAL C 3 25  ? 157.247 158.943 208.288 1.00 64.57  ? 48  VAL C CG2 1 
ATOM   6106  N N   . ASN C 3 26  ? 156.273 163.654 207.793 1.00 70.19  ? 49  ASN C N   1 
ATOM   6107  C CA  . ASN C 3 26  ? 156.416 165.058 208.150 1.00 70.19  ? 49  ASN C CA  1 
ATOM   6108  C C   . ASN C 3 26  ? 156.233 165.230 209.652 1.00 70.19  ? 49  ASN C C   1 
ATOM   6109  O O   . ASN C 3 26  ? 155.228 164.790 210.219 1.00 70.19  ? 49  ASN C O   1 
ATOM   6110  C CB  . ASN C 3 26  ? 155.401 165.910 207.389 1.00 70.19  ? 49  ASN C CB  1 
ATOM   6111  C CG  . ASN C 3 26  ? 155.538 165.774 205.886 1.00 70.19  ? 49  ASN C CG  1 
ATOM   6112  O OD1 . ASN C 3 26  ? 156.329 166.477 205.258 1.00 70.19  ? 49  ASN C OD1 1 
ATOM   6113  N ND2 . ASN C 3 26  ? 154.764 164.868 205.301 1.00 70.19  ? 49  ASN C ND2 1 
ATOM   6114  N N   . LEU C 3 27  ? 157.205 165.873 210.295 1.00 92.78  ? 50  LEU C N   1 
ATOM   6115  C CA  . LEU C 3 27  ? 157.206 166.046 211.741 1.00 92.78  ? 50  LEU C CA  1 
ATOM   6116  C C   . LEU C 3 27  ? 157.386 167.519 212.073 1.00 92.78  ? 50  LEU C C   1 
ATOM   6117  O O   . LEU C 3 27  ? 158.286 168.173 211.537 1.00 92.78  ? 50  LEU C O   1 
ATOM   6118  C CB  . LEU C 3 27  ? 158.316 165.215 212.392 1.00 92.78  ? 50  LEU C CB  1 
ATOM   6119  C CG  . LEU C 3 27  ? 158.440 165.302 213.913 1.00 92.78  ? 50  LEU C CG  1 
ATOM   6120  C CD1 . LEU C 3 27  ? 157.086 165.094 214.571 1.00 92.78  ? 50  LEU C CD1 1 
ATOM   6121  C CD2 . LEU C 3 27  ? 159.449 164.288 214.425 1.00 92.78  ? 50  LEU C CD2 1 
ATOM   6122  N N   . GLU C 3 28  ? 156.532 168.033 212.956 1.00 108.83 ? 51  GLU C N   1 
ATOM   6123  C CA  . GLU C 3 28  ? 156.597 169.416 213.405 1.00 108.83 ? 51  GLU C CA  1 
ATOM   6124  C C   . GLU C 3 28  ? 156.644 169.449 214.925 1.00 108.83 ? 51  GLU C C   1 
ATOM   6125  O O   . GLU C 3 28  ? 155.931 168.693 215.592 1.00 108.83 ? 51  GLU C O   1 
ATOM   6126  C CB  . GLU C 3 28  ? 155.396 170.228 212.902 1.00 108.83 ? 51  GLU C CB  1 
ATOM   6127  C CG  . GLU C 3 28  ? 154.960 169.887 211.487 1.00 108.83 ? 51  GLU C CG  1 
ATOM   6128  C CD  . GLU C 3 28  ? 153.745 170.677 211.046 1.00 108.83 ? 51  GLU C CD  1 
ATOM   6129  O OE1 . GLU C 3 28  ? 153.903 171.863 210.688 1.00 108.83 ? 51  GLU C OE1 1 
ATOM   6130  O OE2 . GLU C 3 28  ? 152.631 170.113 211.057 1.00 108.83 ? 51  GLU C OE2 1 
ATOM   6131  N N   . TRP C 3 29  ? 157.484 170.327 215.469 1.00 118.41 ? 52  TRP C N   1 
ATOM   6132  C CA  . TRP C 3 29  ? 157.626 170.439 216.913 1.00 118.41 ? 52  TRP C CA  1 
ATOM   6133  C C   . TRP C 3 29  ? 158.181 171.812 217.258 1.00 118.41 ? 52  TRP C C   1 
ATOM   6134  O O   . TRP C 3 29  ? 158.941 172.402 216.485 1.00 118.41 ? 52  TRP C O   1 
ATOM   6135  C CB  . TRP C 3 29  ? 158.537 169.342 217.474 1.00 118.41 ? 52  TRP C CB  1 
ATOM   6136  C CG  . TRP C 3 29  ? 159.989 169.554 217.172 1.00 118.41 ? 52  TRP C CG  1 
ATOM   6137  C CD1 . TRP C 3 29  ? 160.905 170.187 217.960 1.00 118.41 ? 52  TRP C CD1 1 
ATOM   6138  C CD2 . TRP C 3 29  ? 160.692 169.132 215.998 1.00 118.41 ? 52  TRP C CD2 1 
ATOM   6139  N NE1 . TRP C 3 29  ? 162.136 170.186 217.349 1.00 118.41 ? 52  TRP C NE1 1 
ATOM   6140  C CE2 . TRP C 3 29  ? 162.032 169.544 216.143 1.00 118.41 ? 52  TRP C CE2 1 
ATOM   6141  C CE3 . TRP C 3 29  ? 160.320 168.445 214.839 1.00 118.41 ? 52  TRP C CE3 1 
ATOM   6142  C CZ2 . TRP C 3 29  ? 162.999 169.292 215.174 1.00 118.41 ? 52  TRP C CZ2 1 
ATOM   6143  C CZ3 . TRP C 3 29  ? 161.281 168.197 213.878 1.00 118.41 ? 52  TRP C CZ3 1 
ATOM   6144  C CH2 . TRP C 3 29  ? 162.605 168.619 214.051 1.00 118.41 ? 52  TRP C CH2 1 
ATOM   6145  N N   . THR C 3 30  ? 157.787 172.312 218.427 1.00 132.69 ? 53  THR C N   1 
ATOM   6146  C CA  . THR C 3 30  ? 158.287 173.569 218.965 1.00 132.69 ? 53  THR C CA  1 
ATOM   6147  C C   . THR C 3 30  ? 158.813 173.333 220.374 1.00 132.69 ? 53  THR C C   1 
ATOM   6148  O O   . THR C 3 30  ? 158.632 172.262 220.959 1.00 132.69 ? 53  THR C O   1 
ATOM   6149  C CB  . THR C 3 30  ? 157.202 174.656 218.985 1.00 132.69 ? 53  THR C CB  1 
ATOM   6150  O OG1 . THR C 3 30  ? 156.334 174.448 220.106 1.00 132.69 ? 53  THR C OG1 1 
ATOM   6151  C CG2 . THR C 3 30  ? 156.384 174.633 217.701 1.00 132.69 ? 53  THR C CG2 1 
ATOM   6152  N N   . VAL C 3 31  ? 159.472 174.354 220.922 1.00 155.51 ? 54  VAL C N   1 
ATOM   6153  C CA  . VAL C 3 31  ? 160.012 174.309 222.272 1.00 155.51 ? 54  VAL C CA  1 
ATOM   6154  C C   . VAL C 3 31  ? 159.513 175.523 223.048 1.00 155.51 ? 54  VAL C C   1 
ATOM   6155  O O   . VAL C 3 31  ? 159.728 176.660 222.620 1.00 155.51 ? 54  VAL C O   1 
ATOM   6156  C CB  . VAL C 3 31  ? 161.550 174.249 222.289 1.00 155.51 ? 54  VAL C CB  1 
ATOM   6157  C CG1 . VAL C 3 31  ? 162.159 175.345 221.418 1.00 155.51 ? 54  VAL C CG1 1 
ATOM   6158  C CG2 . VAL C 3 31  ? 162.069 174.346 223.716 1.00 155.51 ? 54  VAL C CG2 1 
ATOM   6159  N N   . PRO C 3 32  ? 158.812 175.341 224.171 1.00 174.62 ? 55  PRO C N   1 
ATOM   6160  C CA  . PRO C 3 32  ? 158.346 176.498 224.948 1.00 174.62 ? 55  PRO C CA  1 
ATOM   6161  C C   . PRO C 3 32  ? 159.387 177.068 225.896 1.00 174.62 ? 55  PRO C C   1 
ATOM   6162  O O   . PRO C 3 32  ? 159.164 178.154 226.448 1.00 174.62 ? 55  PRO C O   1 
ATOM   6163  C CB  . PRO C 3 32  ? 157.146 175.934 225.734 1.00 174.62 ? 55  PRO C CB  1 
ATOM   6164  C CG  . PRO C 3 32  ? 156.912 174.536 225.191 1.00 174.62 ? 55  PRO C CG  1 
ATOM   6165  C CD  . PRO C 3 32  ? 158.230 174.085 224.662 1.00 174.62 ? 55  PRO C CD  1 
ATOM   6166  N N   . ALA C 3 33  ? 160.509 176.380 226.102 1.00 190.86 ? 56  ALA C N   1 
ATOM   6167  C CA  . ALA C 3 33  ? 161.512 176.787 227.076 1.00 190.86 ? 56  ALA C CA  1 
ATOM   6168  C C   . ALA C 3 33  ? 162.480 177.839 226.544 1.00 190.86 ? 56  ALA C C   1 
ATOM   6169  O O   . ALA C 3 33  ? 163.534 178.052 227.157 1.00 190.86 ? 56  ALA C O   1 
ATOM   6170  C CB  . ALA C 3 33  ? 162.292 175.565 227.567 1.00 190.86 ? 56  ALA C CB  1 
ATOM   6171  N N   . LEU C 3 34  ? 162.164 178.500 225.433 1.00 200.45 ? 57  LEU C N   1 
ATOM   6172  C CA  . LEU C 3 34  ? 163.039 179.535 224.904 1.00 200.45 ? 57  LEU C CA  1 
ATOM   6173  C C   . LEU C 3 34  ? 162.746 180.872 225.572 1.00 200.45 ? 57  LEU C C   1 
ATOM   6174  O O   . LEU C 3 34  ? 161.594 181.192 225.881 1.00 200.45 ? 57  LEU C O   1 
ATOM   6175  C CB  . LEU C 3 34  ? 162.881 179.656 223.386 1.00 200.45 ? 57  LEU C CB  1 
ATOM   6176  C CG  . LEU C 3 34  ? 161.506 179.992 222.803 1.00 200.45 ? 57  LEU C CG  1 
ATOM   6177  C CD1 . LEU C 3 34  ? 161.364 181.488 222.566 1.00 200.45 ? 57  LEU C CD1 1 
ATOM   6178  C CD2 . LEU C 3 34  ? 161.282 179.229 221.509 1.00 200.45 ? 57  LEU C CD2 1 
ATOM   6179  N N   . THR C 3 35  ? 163.800 181.651 225.798 1.00 213.13 ? 58  THR C N   1 
ATOM   6180  C CA  . THR C 3 35  ? 163.695 182.966 226.420 1.00 213.13 ? 58  THR C CA  1 
ATOM   6181  C C   . THR C 3 35  ? 164.093 184.101 225.491 1.00 213.13 ? 58  THR C C   1 
ATOM   6182  O O   . THR C 3 35  ? 163.408 185.126 225.448 1.00 213.13 ? 58  THR C O   1 
ATOM   6183  C CB  . THR C 3 35  ? 164.561 183.023 227.685 1.00 213.13 ? 58  THR C CB  1 
ATOM   6184  O OG1 . THR C 3 35  ? 164.149 181.995 228.594 1.00 213.13 ? 58  THR C OG1 1 
ATOM   6185  C CG2 . THR C 3 35  ? 164.428 184.376 228.369 1.00 213.13 ? 58  THR C CG2 1 
ATOM   6186  N N   . HIS C 3 36  ? 165.176 183.941 224.735 1.00 219.75 ? 59  HIS C N   1 
ATOM   6187  C CA  . HIS C 3 36  ? 165.640 184.976 223.822 1.00 219.75 ? 59  HIS C CA  1 
ATOM   6188  C C   . HIS C 3 36  ? 164.775 184.972 222.562 1.00 219.75 ? 59  HIS C C   1 
ATOM   6189  O O   . HIS C 3 36  ? 163.755 184.282 222.477 1.00 219.75 ? 59  HIS C O   1 
ATOM   6190  C CB  . HIS C 3 36  ? 167.120 184.778 223.507 1.00 219.75 ? 59  HIS C CB  1 
ATOM   6191  C CG  . HIS C 3 36  ? 168.008 184.839 224.710 1.00 219.75 ? 59  HIS C CG  1 
ATOM   6192  N ND1 . HIS C 3 36  ? 168.042 183.842 225.662 1.00 219.75 ? 59  HIS C ND1 1 
ATOM   6193  C CD2 . HIS C 3 36  ? 168.894 185.778 225.117 1.00 219.75 ? 59  HIS C CD2 1 
ATOM   6194  C CE1 . HIS C 3 36  ? 168.912 184.164 226.603 1.00 219.75 ? 59  HIS C CE1 1 
ATOM   6195  N NE2 . HIS C 3 36  ? 169.443 185.335 226.296 1.00 219.75 ? 59  HIS C NE2 1 
ATOM   6196  N N   . GLU C 3 37  ? 165.181 185.750 221.559 1.00 227.00 ? 60  GLU C N   1 
ATOM   6197  C CA  . GLU C 3 37  ? 164.403 185.889 220.334 1.00 227.00 ? 60  GLU C CA  1 
ATOM   6198  C C   . GLU C 3 37  ? 164.842 184.904 219.254 1.00 227.00 ? 60  GLU C C   1 
ATOM   6199  O O   . GLU C 3 37  ? 164.000 184.269 218.612 1.00 227.00 ? 60  GLU C O   1 
ATOM   6200  C CB  . GLU C 3 37  ? 164.505 187.325 219.811 1.00 227.00 ? 60  GLU C CB  1 
ATOM   6201  C CG  . GLU C 3 37  ? 163.595 187.625 218.630 1.00 227.00 ? 60  GLU C CG  1 
ATOM   6202  C CD  . GLU C 3 37  ? 164.307 187.494 217.298 1.00 227.00 ? 60  GLU C CD  1 
ATOM   6203  O OE1 . GLU C 3 37  ? 165.532 187.733 217.250 1.00 227.00 ? 60  GLU C OE1 1 
ATOM   6204  O OE2 . GLU C 3 37  ? 163.642 187.150 216.298 1.00 227.00 ? 60  GLU C OE2 1 
ATOM   6205  N N   . GLU C 3 38  ? 166.149 184.764 219.043 1.00 222.72 ? 61  GLU C N   1 
ATOM   6206  C CA  . GLU C 3 38  ? 166.662 183.915 217.976 1.00 222.72 ? 61  GLU C CA  1 
ATOM   6207  C C   . GLU C 3 38  ? 167.971 183.281 218.420 1.00 222.72 ? 61  GLU C C   1 
ATOM   6208  O O   . GLU C 3 38  ? 168.906 183.990 218.803 1.00 222.72 ? 61  GLU C O   1 
ATOM   6209  C CB  . GLU C 3 38  ? 166.869 184.718 216.688 1.00 222.72 ? 61  GLU C CB  1 
ATOM   6210  C CG  . GLU C 3 38  ? 167.769 184.043 215.669 1.00 222.72 ? 61  GLU C CG  1 
ATOM   6211  C CD  . GLU C 3 38  ? 167.897 184.840 214.387 1.00 222.72 ? 61  GLU C CD  1 
ATOM   6212  O OE1 . GLU C 3 38  ? 166.925 185.530 214.014 1.00 222.72 ? 61  GLU C OE1 1 
ATOM   6213  O OE2 . GLU C 3 38  ? 168.971 184.777 213.751 1.00 222.72 ? 61  GLU C OE2 1 
ATOM   6214  N N   . LEU C 3 39  ? 168.030 181.952 218.367 1.00 213.70 ? 62  LEU C N   1 
ATOM   6215  C CA  . LEU C 3 39  ? 169.226 181.208 218.736 1.00 213.70 ? 62  LEU C CA  1 
ATOM   6216  C C   . LEU C 3 39  ? 169.393 180.027 217.791 1.00 213.70 ? 62  LEU C C   1 
ATOM   6217  O O   . LEU C 3 39  ? 168.439 179.573 217.154 1.00 213.70 ? 62  LEU C O   1 
ATOM   6218  C CB  . LEU C 3 39  ? 169.169 180.706 220.188 1.00 213.70 ? 62  LEU C CB  1 
ATOM   6219  C CG  . LEU C 3 39  ? 168.802 181.695 221.297 1.00 213.70 ? 62  LEU C CG  1 
ATOM   6220  C CD1 . LEU C 3 39  ? 167.312 181.638 221.596 1.00 213.70 ? 62  LEU C CD1 1 
ATOM   6221  C CD2 . LEU C 3 39  ? 169.615 181.419 222.553 1.00 213.70 ? 62  LEU C CD2 1 
ATOM   6222  N N   . ASN C 3 40  ? 170.625 179.532 217.708 1.00 205.97 ? 63  ASN C N   1 
ATOM   6223  C CA  . ASN C 3 40  ? 170.932 178.350 216.917 1.00 205.97 ? 63  ASN C CA  1 
ATOM   6224  C C   . ASN C 3 40  ? 170.853 177.108 217.794 1.00 205.97 ? 63  ASN C C   1 
ATOM   6225  O O   . ASN C 3 40  ? 171.342 177.102 218.928 1.00 205.97 ? 63  ASN C O   1 
ATOM   6226  C CB  . ASN C 3 40  ? 172.322 178.463 216.288 1.00 205.97 ? 63  ASN C CB  1 
ATOM   6227  C CG  . ASN C 3 40  ? 172.520 179.767 215.542 1.00 205.97 ? 63  ASN C CG  1 
ATOM   6228  O OD1 . ASN C 3 40  ? 171.558 180.395 215.100 1.00 205.97 ? 63  ASN C OD1 1 
ATOM   6229  N ND2 . ASN C 3 40  ? 173.773 180.181 215.396 1.00 205.97 ? 63  ASN C ND2 1 
ATOM   6230  N N   . MET C 3 41  ? 170.233 176.057 217.264 1.00 181.75 ? 64  MET C N   1 
ATOM   6231  C CA  . MET C 3 41  ? 170.003 174.833 218.016 1.00 181.75 ? 64  MET C CA  1 
ATOM   6232  C C   . MET C 3 41  ? 170.402 173.622 217.185 1.00 181.75 ? 64  MET C C   1 
ATOM   6233  O O   . MET C 3 41  ? 170.499 173.685 215.957 1.00 181.75 ? 64  MET C O   1 
ATOM   6234  C CB  . MET C 3 41  ? 168.535 174.708 218.450 1.00 181.75 ? 64  MET C CB  1 
ATOM   6235  C CG  . MET C 3 41  ? 168.076 175.792 219.411 1.00 181.75 ? 64  MET C CG  1 
ATOM   6236  S SD  . MET C 3 41  ? 169.037 175.820 220.935 1.00 181.75 ? 64  MET C SD  1 
ATOM   6237  C CE  . MET C 3 41  ? 168.312 177.231 221.767 1.00 181.75 ? 64  MET C CE  1 
ATOM   6238  N N   . ILE C 3 42  ? 170.636 172.512 217.880 1.00 162.56 ? 65  ILE C N   1 
ATOM   6239  C CA  . ILE C 3 42  ? 170.954 171.229 217.264 1.00 162.56 ? 65  ILE C CA  1 
ATOM   6240  C C   . ILE C 3 42  ? 169.958 170.207 217.790 1.00 162.56 ? 65  ILE C C   1 
ATOM   6241  O O   . ILE C 3 42  ? 169.838 170.020 219.008 1.00 162.56 ? 65  ILE C O   1 
ATOM   6242  C CB  . ILE C 3 42  ? 172.396 170.787 217.558 1.00 162.56 ? 65  ILE C CB  1 
ATOM   6243  C CG1 . ILE C 3 42  ? 173.395 171.734 216.891 1.00 162.56 ? 65  ILE C CG1 1 
ATOM   6244  C CG2 . ILE C 3 42  ? 172.621 169.356 217.091 1.00 162.56 ? 65  ILE C CG2 1 
ATOM   6245  C CD1 . ILE C 3 42  ? 173.901 172.826 217.803 1.00 162.56 ? 65  ILE C CD1 1 
ATOM   6246  N N   . PHE C 3 43  ? 169.247 169.548 216.881 1.00 126.48 ? 66  PHE C N   1 
ATOM   6247  C CA  . PHE C 3 43  ? 168.205 168.587 217.234 1.00 126.48 ? 66  PHE C CA  1 
ATOM   6248  C C   . PHE C 3 43  ? 168.677 167.188 216.852 1.00 126.48 ? 66  PHE C C   1 
ATOM   6249  O O   . PHE C 3 43  ? 168.662 166.817 215.675 1.00 126.48 ? 66  PHE C O   1 
ATOM   6250  C CB  . PHE C 3 43  ? 166.889 168.940 216.547 1.00 126.48 ? 66  PHE C CB  1 
ATOM   6251  C CG  . PHE C 3 43  ? 166.295 170.239 217.007 1.00 126.48 ? 66  PHE C CG  1 
ATOM   6252  C CD1 . PHE C 3 43  ? 165.654 170.327 218.232 1.00 126.48 ? 66  PHE C CD1 1 
ATOM   6253  C CD2 . PHE C 3 43  ? 166.376 171.372 216.216 1.00 126.48 ? 66  PHE C CD2 1 
ATOM   6254  C CE1 . PHE C 3 43  ? 165.106 171.520 218.659 1.00 126.48 ? 66  PHE C CE1 1 
ATOM   6255  C CE2 . PHE C 3 43  ? 165.829 172.569 216.638 1.00 126.48 ? 66  PHE C CE2 1 
ATOM   6256  C CZ  . PHE C 3 43  ? 165.194 172.642 217.861 1.00 126.48 ? 66  PHE C CZ  1 
ATOM   6257  N N   . GLN C 3 44  ? 169.095 166.415 217.851 1.00 114.80 ? 67  GLN C N   1 
ATOM   6258  C CA  . GLN C 3 44  ? 169.462 165.021 217.641 1.00 114.80 ? 67  GLN C CA  1 
ATOM   6259  C C   . GLN C 3 44  ? 168.197 164.174 217.580 1.00 114.80 ? 67  GLN C C   1 
ATOM   6260  O O   . GLN C 3 44  ? 167.389 164.188 218.515 1.00 114.80 ? 67  GLN C O   1 
ATOM   6261  C CB  . GLN C 3 44  ? 170.386 164.538 218.756 1.00 114.80 ? 67  GLN C CB  1 
ATOM   6262  C CG  . GLN C 3 44  ? 170.959 163.151 218.529 1.00 114.80 ? 67  GLN C CG  1 
ATOM   6263  C CD  . GLN C 3 44  ? 171.820 162.683 219.685 1.00 114.80 ? 67  GLN C CD  1 
ATOM   6264  O OE1 . GLN C 3 44  ? 171.575 163.036 220.838 1.00 114.80 ? 67  GLN C OE1 1 
ATOM   6265  N NE2 . GLN C 3 44  ? 172.835 161.884 219.381 1.00 114.80 ? 67  GLN C NE2 1 
ATOM   6266  N N   . ILE C 3 45  ? 168.026 163.439 216.486 1.00 92.81  ? 68  ILE C N   1 
ATOM   6267  C CA  . ILE C 3 45  ? 166.816 162.668 216.226 1.00 92.81  ? 68  ILE C CA  1 
ATOM   6268  C C   . ILE C 3 45  ? 167.158 161.187 216.287 1.00 92.81  ? 68  ILE C C   1 
ATOM   6269  O O   . ILE C 3 45  ? 168.173 160.754 215.729 1.00 92.81  ? 68  ILE C O   1 
ATOM   6270  C CB  . ILE C 3 45  ? 166.201 163.038 214.866 1.00 92.81  ? 68  ILE C CB  1 
ATOM   6271  C CG1 . ILE C 3 45  ? 166.043 164.555 214.758 1.00 92.81  ? 68  ILE C CG1 1 
ATOM   6272  C CG2 . ILE C 3 45  ? 164.862 162.345 214.677 1.00 92.81  ? 68  ILE C CG2 1 
ATOM   6273  C CD1 . ILE C 3 45  ? 165.623 165.029 213.390 1.00 92.81  ? 68  ILE C CD1 1 
ATOM   6274  N N   . GLU C 3 46  ? 166.313 160.414 216.965 1.00 87.64  ? 69  GLU C N   1 
ATOM   6275  C CA  . GLU C 3 46  ? 166.482 158.974 217.098 1.00 87.64  ? 69  GLU C CA  1 
ATOM   6276  C C   . GLU C 3 46  ? 165.210 158.280 216.632 1.00 87.64  ? 69  GLU C C   1 
ATOM   6277  O O   . GLU C 3 46  ? 164.106 158.671 217.026 1.00 87.64  ? 69  GLU C O   1 
ATOM   6278  C CB  . GLU C 3 46  ? 166.804 158.589 218.544 1.00 87.64  ? 69  GLU C CB  1 
ATOM   6279  C CG  . GLU C 3 46  ? 166.922 157.095 218.780 1.00 87.64  ? 69  GLU C CG  1 
ATOM   6280  C CD  . GLU C 3 46  ? 167.468 156.767 220.155 1.00 87.64  ? 69  GLU C CD  1 
ATOM   6281  O OE1 . GLU C 3 46  ? 168.212 155.772 220.279 1.00 87.64  ? 69  GLU C OE1 1 
ATOM   6282  O OE2 . GLU C 3 46  ? 167.153 157.505 221.111 1.00 87.64  ? 69  GLU C OE2 1 
ATOM   6283  N N   . ILE C 3 47  ? 165.366 157.255 215.798 1.00 72.12  ? 70  ILE C N   1 
ATOM   6284  C CA  . ILE C 3 47  ? 164.246 156.537 215.203 1.00 72.12  ? 70  ILE C CA  1 
ATOM   6285  C C   . ILE C 3 47  ? 164.335 155.071 215.599 1.00 72.12  ? 70  ILE C C   1 
ATOM   6286  O O   . ILE C 3 47  ? 165.425 154.490 215.625 1.00 72.12  ? 70  ILE C O   1 
ATOM   6287  C CB  . ILE C 3 47  ? 164.231 156.691 213.668 1.00 72.12  ? 70  ILE C CB  1 
ATOM   6288  C CG1 . ILE C 3 47  ? 164.342 158.166 213.284 1.00 72.12  ? 70  ILE C CG1 1 
ATOM   6289  C CG2 . ILE C 3 47  ? 162.969 156.081 213.079 1.00 72.12  ? 70  ILE C CG2 1 
ATOM   6290  C CD1 . ILE C 3 47  ? 164.391 158.407 211.795 1.00 72.12  ? 70  ILE C CD1 1 
ATOM   6291  N N   . SER C 3 48  ? 163.187 154.476 215.909 1.00 77.39  ? 71  SER C N   1 
ATOM   6292  C CA  . SER C 3 48  ? 163.096 153.076 216.291 1.00 77.39  ? 71  SER C CA  1 
ATOM   6293  C C   . SER C 3 48  ? 162.122 152.347 215.372 1.00 77.39  ? 71  SER C C   1 
ATOM   6294  O O   . SER C 3 48  ? 161.440 152.953 214.542 1.00 77.39  ? 71  SER C O   1 
ATOM   6295  C CB  . SER C 3 48  ? 162.663 152.933 217.755 1.00 77.39  ? 71  SER C CB  1 
ATOM   6296  O OG  . SER C 3 48  ? 163.398 153.812 218.588 1.00 77.39  ? 71  SER C OG  1 
ATOM   6297  N N   . ARG C 3 49  ? 162.063 151.025 215.530 1.00 71.04  ? 72  ARG C N   1 
ATOM   6298  C CA  . ARG C 3 49  ? 161.214 150.193 214.686 1.00 71.04  ? 72  ARG C CA  1 
ATOM   6299  C C   . ARG C 3 49  ? 160.751 148.974 215.470 1.00 71.04  ? 72  ARG C C   1 
ATOM   6300  O O   . ARG C 3 49  ? 161.575 148.258 216.047 1.00 71.04  ? 72  ARG C O   1 
ATOM   6301  C CB  . ARG C 3 49  ? 161.956 149.758 213.418 1.00 71.04  ? 72  ARG C CB  1 
ATOM   6302  C CG  . ARG C 3 49  ? 161.105 148.964 212.442 1.00 71.04  ? 72  ARG C CG  1 
ATOM   6303  C CD  . ARG C 3 49  ? 161.892 148.606 211.191 1.00 71.04  ? 72  ARG C CD  1 
ATOM   6304  N NE  . ARG C 3 49  ? 162.409 149.791 210.511 1.00 71.04  ? 72  ARG C NE  1 
ATOM   6305  C CZ  . ARG C 3 49  ? 163.201 149.753 209.445 1.00 71.04  ? 72  ARG C CZ  1 
ATOM   6306  N NH1 . ARG C 3 49  ? 163.571 148.588 208.932 1.00 71.04  ? 72  ARG C NH1 1 
ATOM   6307  N NH2 . ARG C 3 49  ? 163.624 150.881 208.890 1.00 71.04  ? 72  ARG C NH2 1 
ATOM   6308  N N   . LEU C 3 50  ? 159.431 148.774 215.510 1.00 77.93  ? 73  LEU C N   1 
ATOM   6309  C CA  . LEU C 3 50  ? 158.774 147.599 216.082 1.00 77.93  ? 73  LEU C CA  1 
ATOM   6310  C C   . LEU C 3 50  ? 158.841 147.579 217.606 1.00 77.93  ? 73  LEU C C   1 
ATOM   6311  O O   . LEU C 3 50  ? 158.175 146.759 218.246 1.00 77.93  ? 73  LEU C O   1 
ATOM   6312  C CB  . LEU C 3 50  ? 159.374 146.312 215.507 1.00 77.93  ? 73  LEU C CB  1 
ATOM   6313  C CG  . LEU C 3 50  ? 158.478 145.072 215.508 1.00 77.93  ? 73  LEU C CG  1 
ATOM   6314  C CD1 . LEU C 3 50  ? 157.195 145.333 214.736 1.00 77.93  ? 73  LEU C CD1 1 
ATOM   6315  C CD2 . LEU C 3 50  ? 159.219 143.876 214.930 1.00 77.93  ? 73  LEU C CD2 1 
ATOM   6316  N N   . ASN C 3 51  ? 159.618 148.490 218.190 1.00 84.37  ? 74  ASN C N   1 
ATOM   6317  C CA  . ASN C 3 51  ? 159.674 148.740 219.627 1.00 84.37  ? 74  ASN C CA  1 
ATOM   6318  C C   . ASN C 3 51  ? 160.644 149.889 219.856 1.00 84.37  ? 74  ASN C C   1 
ATOM   6319  O O   . ASN C 3 51  ? 161.453 150.221 218.985 1.00 84.37  ? 74  ASN C O   1 
ATOM   6320  C CB  . ASN C 3 51  ? 160.096 147.508 220.443 1.00 84.37  ? 74  ASN C CB  1 
ATOM   6321  C CG  . ASN C 3 51  ? 161.332 146.821 219.892 1.00 84.37  ? 74  ASN C CG  1 
ATOM   6322  O OD1 . ASN C 3 51  ? 161.928 147.266 218.911 1.00 84.37  ? 74  ASN C OD1 1 
ATOM   6323  N ND2 . ASN C 3 51  ? 161.720 145.720 220.534 1.00 84.37  ? 74  ASN C ND2 1 
ATOM   6324  N N   . ILE C 3 52  ? 160.557 150.490 221.048 1.00 93.15  ? 75  ILE C N   1 
ATOM   6325  C CA  . ILE C 3 52  ? 161.346 151.682 221.357 1.00 93.15  ? 75  ILE C CA  1 
ATOM   6326  C C   . ILE C 3 52  ? 162.792 151.373 221.703 1.00 93.15  ? 75  ILE C C   1 
ATOM   6327  O O   . ILE C 3 52  ? 163.547 152.296 222.034 1.00 93.15  ? 75  ILE C O   1 
ATOM   6328  C CB  . ILE C 3 52  ? 160.715 152.474 222.520 1.00 93.15  ? 75  ILE C CB  1 
ATOM   6329  C CG1 . ILE C 3 52  ? 160.699 151.629 223.794 1.00 93.15  ? 75  ILE C CG1 1 
ATOM   6330  C CG2 . ILE C 3 52  ? 159.309 152.923 222.157 1.00 93.15  ? 75  ILE C CG2 1 
ATOM   6331  C CD1 . ILE C 3 52  ? 160.128 152.349 224.996 1.00 93.15  ? 75  ILE C CD1 1 
ATOM   6332  N N   . SER C 3 53  ? 163.207 150.109 221.639 1.00 86.18  ? 76  SER C N   1 
ATOM   6333  C CA  . SER C 3 53  ? 164.569 149.723 221.979 1.00 86.18  ? 76  SER C CA  1 
ATOM   6334  C C   . SER C 3 53  ? 165.407 149.342 220.767 1.00 86.18  ? 76  SER C C   1 
ATOM   6335  O O   . SER C 3 53  ? 166.566 148.947 220.935 1.00 86.18  ? 76  SER C O   1 
ATOM   6336  C CB  . SER C 3 53  ? 164.553 148.561 222.979 1.00 86.18  ? 76  SER C CB  1 
ATOM   6337  O OG  . SER C 3 53  ? 165.803 148.438 223.634 1.00 86.18  ? 76  SER C OG  1 
ATOM   6338  N N   . ASN C 3 54  ? 164.863 149.446 219.559 1.00 83.68  ? 77  ASN C N   1 
ATOM   6339  C CA  . ASN C 3 54  ? 165.569 149.075 218.334 1.00 83.68  ? 77  ASN C CA  1 
ATOM   6340  C C   . ASN C 3 54  ? 165.995 150.354 217.615 1.00 83.68  ? 77  ASN C C   1 
ATOM   6341  O O   . ASN C 3 54  ? 165.307 150.835 216.714 1.00 83.68  ? 77  ASN C O   1 
ATOM   6342  C CB  . ASN C 3 54  ? 164.688 148.201 217.445 1.00 83.68  ? 77  ASN C CB  1 
ATOM   6343  C CG  . ASN C 3 54  ? 165.437 147.638 216.254 1.00 83.68  ? 77  ASN C CG  1 
ATOM   6344  O OD1 . ASN C 3 54  ? 166.667 147.620 216.232 1.00 83.68  ? 77  ASN C OD1 1 
ATOM   6345  N ND2 . ASN C 3 54  ? 164.696 147.171 215.256 1.00 83.68  ? 77  ASN C ND2 1 
ATOM   6346  N N   . THR C 3 55  ? 167.145 150.894 218.011 1.00 76.54  ? 78  THR C N   1 
ATOM   6347  C CA  . THR C 3 55  ? 167.671 152.095 217.374 1.00 76.54  ? 78  THR C CA  1 
ATOM   6348  C C   . THR C 3 55  ? 168.201 151.750 215.988 1.00 76.54  ? 78  THR C C   1 
ATOM   6349  O O   . THR C 3 55  ? 169.052 150.867 215.844 1.00 76.54  ? 78  THR C O   1 
ATOM   6350  C CB  . THR C 3 55  ? 168.772 152.713 218.231 1.00 76.54  ? 78  THR C CB  1 
ATOM   6351  O OG1 . THR C 3 55  ? 168.244 153.056 219.518 1.00 76.54  ? 78  THR C OG1 1 
ATOM   6352  C CG2 . THR C 3 55  ? 169.324 153.965 217.566 1.00 76.54  ? 78  THR C CG2 1 
ATOM   6353  N N   . ILE C 3 56  ? 167.700 152.445 214.969 1.00 66.91  ? 79  ILE C N   1 
ATOM   6354  C CA  . ILE C 3 56  ? 168.080 152.172 213.587 1.00 66.91  ? 79  ILE C CA  1 
ATOM   6355  C C   . ILE C 3 56  ? 168.651 153.386 212.872 1.00 66.91  ? 79  ILE C C   1 
ATOM   6356  O O   . ILE C 3 56  ? 169.248 153.223 211.797 1.00 66.91  ? 79  ILE C O   1 
ATOM   6357  C CB  . ILE C 3 56  ? 166.895 151.601 212.778 1.00 66.91  ? 79  ILE C CB  1 
ATOM   6358  C CG1 . ILE C 3 56  ? 165.789 152.648 212.641 1.00 66.91  ? 79  ILE C CG1 1 
ATOM   6359  C CG2 . ILE C 3 56  ? 166.358 150.339 213.433 1.00 66.91  ? 79  ILE C CG2 1 
ATOM   6360  C CD1 . ILE C 3 56  ? 164.606 152.180 211.827 1.00 66.91  ? 79  ILE C CD1 1 
ATOM   6361  N N   . TRP C 3 57  ? 168.495 154.591 213.415 1.00 71.88  ? 80  TRP C N   1 
ATOM   6362  C CA  . TRP C 3 57  ? 168.982 155.787 212.742 1.00 71.88  ? 80  TRP C CA  1 
ATOM   6363  C C   . TRP C 3 57  ? 169.190 156.892 213.766 1.00 71.88  ? 80  TRP C C   1 
ATOM   6364  O O   . TRP C 3 57  ? 168.341 157.110 214.633 1.00 71.88  ? 80  TRP C O   1 
ATOM   6365  C CB  . TRP C 3 57  ? 168.004 156.249 211.655 1.00 71.88  ? 80  TRP C CB  1 
ATOM   6366  C CG  . TRP C 3 57  ? 168.502 157.407 210.847 1.00 71.88  ? 80  TRP C CG  1 
ATOM   6367  C CD1 . TRP C 3 57  ? 168.442 158.728 211.183 1.00 71.88  ? 80  TRP C CD1 1 
ATOM   6368  C CD2 . TRP C 3 57  ? 169.132 157.348 209.562 1.00 71.88  ? 80  TRP C CD2 1 
ATOM   6369  N NE1 . TRP C 3 57  ? 168.997 159.495 210.188 1.00 71.88  ? 80  TRP C NE1 1 
ATOM   6370  C CE2 . TRP C 3 57  ? 169.428 158.671 209.182 1.00 71.88  ? 80  TRP C CE2 1 
ATOM   6371  C CE3 . TRP C 3 57  ? 169.474 156.305 208.697 1.00 71.88  ? 80  TRP C CE3 1 
ATOM   6372  C CZ2 . TRP C 3 57  ? 170.051 158.979 207.975 1.00 71.88  ? 80  TRP C CZ2 1 
ATOM   6373  C CZ3 . TRP C 3 57  ? 170.093 156.612 207.499 1.00 71.88  ? 80  TRP C CZ3 1 
ATOM   6374  C CH2 . TRP C 3 57  ? 170.374 157.938 207.149 1.00 71.88  ? 80  TRP C CH2 1 
ATOM   6375  N N   . VAL C 3 58  ? 170.322 157.583 213.654 1.00 77.57  ? 81  VAL C N   1 
ATOM   6376  C CA  . VAL C 3 58  ? 170.647 158.728 214.497 1.00 77.57  ? 81  VAL C CA  1 
ATOM   6377  C C   . VAL C 3 58  ? 171.187 159.832 213.601 1.00 77.57  ? 81  VAL C C   1 
ATOM   6378  O O   . VAL C 3 58  ? 172.142 159.612 212.847 1.00 77.57  ? 81  VAL C O   1 
ATOM   6379  C CB  . VAL C 3 58  ? 171.671 158.369 215.591 1.00 77.57  ? 81  VAL C CB  1 
ATOM   6380  C CG1 . VAL C 3 58  ? 172.108 159.620 216.336 1.00 77.57  ? 81  VAL C CG1 1 
ATOM   6381  C CG2 . VAL C 3 58  ? 171.087 157.350 216.557 1.00 77.57  ? 81  VAL C CG2 1 
ATOM   6382  N N   . GLU C 3 59  ? 170.581 161.014 213.681 1.00 89.28  ? 82  GLU C N   1 
ATOM   6383  C CA  . GLU C 3 59  ? 170.961 162.135 212.836 1.00 89.28  ? 82  GLU C CA  1 
ATOM   6384  C C   . GLU C 3 59  ? 171.023 163.406 213.669 1.00 89.28  ? 82  GLU C C   1 
ATOM   6385  O O   . GLU C 3 59  ? 170.372 163.517 214.711 1.00 89.28  ? 82  GLU C O   1 
ATOM   6386  C CB  . GLU C 3 59  ? 169.979 162.321 211.672 1.00 89.28  ? 82  GLU C CB  1 
ATOM   6387  C CG  . GLU C 3 59  ? 170.590 162.960 210.438 1.00 89.28  ? 82  GLU C CG  1 
ATOM   6388  C CD  . GLU C 3 59  ? 169.547 163.352 209.411 1.00 89.28  ? 82  GLU C CD  1 
ATOM   6389  O OE1 . GLU C 3 59  ? 168.720 164.237 209.712 1.00 89.28  ? 82  GLU C OE1 1 
ATOM   6390  O OE2 . GLU C 3 59  ? 169.554 162.774 208.304 1.00 89.28  ? 82  GLU C OE2 1 
ATOM   6391  N N   . ASN C 3 60  ? 171.817 164.365 213.198 1.00 105.74 ? 83  ASN C N   1 
ATOM   6392  C CA  . ASN C 3 60  ? 171.959 165.667 213.836 1.00 105.74 ? 83  ASN C CA  1 
ATOM   6393  C C   . ASN C 3 60  ? 171.433 166.734 212.888 1.00 105.74 ? 83  ASN C C   1 
ATOM   6394  O O   . ASN C 3 60  ? 171.921 166.862 211.760 1.00 105.74 ? 83  ASN C O   1 
ATOM   6395  C CB  . ASN C 3 60  ? 173.418 165.944 214.207 1.00 105.74 ? 83  ASN C CB  1 
ATOM   6396  C CG  . ASN C 3 60  ? 173.957 164.959 215.224 1.00 105.74 ? 83  ASN C CG  1 
ATOM   6397  O OD1 . ASN C 3 60  ? 173.201 164.371 215.997 1.00 105.74 ? 83  ASN C OD1 1 
ATOM   6398  N ND2 . ASN C 3 60  ? 175.272 164.775 215.230 1.00 105.74 ? 83  ASN C ND2 1 
ATOM   6399  N N   . TYR C 3 61  ? 170.440 167.494 213.344 1.00 128.20 ? 84  TYR C N   1 
ATOM   6400  C CA  . TYR C 3 61  ? 169.793 168.527 212.540 1.00 128.20 ? 84  TYR C CA  1 
ATOM   6401  C C   . TYR C 3 61  ? 169.997 169.871 213.226 1.00 128.20 ? 84  TYR C C   1 
ATOM   6402  O O   . TYR C 3 61  ? 169.380 170.144 214.262 1.00 128.20 ? 84  TYR C O   1 
ATOM   6403  C CB  . TYR C 3 61  ? 168.307 168.221 212.356 1.00 128.20 ? 84  TYR C CB  1 
ATOM   6404  C CG  . TYR C 3 61  ? 167.551 169.261 211.562 1.00 128.20 ? 84  TYR C CG  1 
ATOM   6405  C CD1 . TYR C 3 61  ? 166.694 170.155 212.190 1.00 128.20 ? 84  TYR C CD1 1 
ATOM   6406  C CD2 . TYR C 3 61  ? 167.690 169.345 210.183 1.00 128.20 ? 84  TYR C CD2 1 
ATOM   6407  C CE1 . TYR C 3 61  ? 165.999 171.105 211.468 1.00 128.20 ? 84  TYR C CE1 1 
ATOM   6408  C CE2 . TYR C 3 61  ? 166.999 170.293 209.452 1.00 128.20 ? 84  TYR C CE2 1 
ATOM   6409  C CZ  . TYR C 3 61  ? 166.154 171.169 210.099 1.00 128.20 ? 84  TYR C CZ  1 
ATOM   6410  O OH  . TYR C 3 61  ? 165.464 172.114 209.376 1.00 128.20 ? 84  TYR C OH  1 
ATOM   6411  N N   . SER C 3 62  ? 170.858 170.705 212.651 1.00 153.71 ? 85  SER C N   1 
ATOM   6412  C CA  . SER C 3 62  ? 171.154 172.027 213.188 1.00 153.71 ? 85  SER C CA  1 
ATOM   6413  C C   . SER C 3 62  ? 170.473 173.082 212.326 1.00 153.71 ? 85  SER C C   1 
ATOM   6414  O O   . SER C 3 62  ? 170.731 173.165 211.120 1.00 153.71 ? 85  SER C O   1 
ATOM   6415  C CB  . SER C 3 62  ? 172.662 172.269 213.242 1.00 153.71 ? 85  SER C CB  1 
ATOM   6416  O OG  . SER C 3 62  ? 172.973 173.350 214.105 1.00 153.71 ? 85  SER C OG  1 
ATOM   6417  N N   . THR C 3 63  ? 169.609 173.885 212.945 1.00 169.23 ? 86  THR C N   1 
ATOM   6418  C CA  . THR C 3 63  ? 168.891 174.934 212.232 1.00 169.23 ? 86  THR C CA  1 
ATOM   6419  C C   . THR C 3 63  ? 168.466 175.997 213.232 1.00 169.23 ? 86  THR C C   1 
ATOM   6420  O O   . THR C 3 63  ? 167.928 175.670 214.294 1.00 169.23 ? 86  THR C O   1 
ATOM   6421  C CB  . THR C 3 63  ? 167.669 174.370 211.495 1.00 169.23 ? 86  THR C CB  1 
ATOM   6422  O OG1 . THR C 3 63  ? 168.103 173.507 210.437 1.00 169.23 ? 86  THR C OG1 1 
ATOM   6423  C CG2 . THR C 3 63  ? 166.827 175.495 210.909 1.00 169.23 ? 86  THR C CG2 1 
ATOM   6424  N N   . THR C 3 64  ? 168.712 177.260 212.892 1.00 197.41 ? 87  THR C N   1 
ATOM   6425  C CA  . THR C 3 64  ? 168.336 178.364 213.765 1.00 197.41 ? 87  THR C CA  1 
ATOM   6426  C C   . THR C 3 64  ? 166.819 178.446 213.892 1.00 197.41 ? 87  THR C C   1 
ATOM   6427  O O   . THR C 3 64  ? 166.100 178.440 212.888 1.00 197.41 ? 87  THR C O   1 
ATOM   6428  C CB  . THR C 3 64  ? 168.894 179.680 213.224 1.00 197.41 ? 87  THR C CB  1 
ATOM   6429  O OG1 . THR C 3 64  ? 170.326 179.628 213.219 1.00 197.41 ? 87  THR C OG1 1 
ATOM   6430  C CG2 . THR C 3 64  ? 168.437 180.847 214.082 1.00 197.41 ? 87  THR C CG2 1 
ATOM   6431  N N   . VAL C 3 65  ? 166.335 178.523 215.129 1.00 206.33 ? 88  VAL C N   1 
ATOM   6432  C CA  . VAL C 3 65  ? 164.910 178.600 215.421 1.00 206.33 ? 88  VAL C CA  1 
ATOM   6433  C C   . VAL C 3 65  ? 164.633 179.913 216.138 1.00 206.33 ? 88  VAL C C   1 
ATOM   6434  O O   . VAL C 3 65  ? 165.421 180.351 216.984 1.00 206.33 ? 88  VAL C O   1 
ATOM   6435  C CB  . VAL C 3 65  ? 164.439 177.393 216.263 1.00 206.33 ? 88  VAL C CB  1 
ATOM   6436  C CG1 . VAL C 3 65  ? 165.274 177.258 217.529 1.00 206.33 ? 88  VAL C CG1 1 
ATOM   6437  C CG2 . VAL C 3 65  ? 162.956 177.508 216.597 1.00 206.33 ? 88  VAL C CG2 1 
ATOM   6438  N N   . LYS C 3 66  ? 163.518 180.549 215.787 1.00 208.45 ? 89  LYS C N   1 
ATOM   6439  C CA  . LYS C 3 66  ? 163.113 181.809 216.384 1.00 208.45 ? 89  LYS C CA  1 
ATOM   6440  C C   . LYS C 3 66  ? 161.971 181.577 217.371 1.00 208.45 ? 89  LYS C C   1 
ATOM   6441  O O   . LYS C 3 66  ? 161.531 180.449 217.605 1.00 208.45 ? 89  LYS C O   1 
ATOM   6442  C CB  . LYS C 3 66  ? 162.707 182.808 215.298 1.00 208.45 ? 89  LYS C CB  1 
ATOM   6443  C CG  . LYS C 3 66  ? 163.796 183.096 214.279 1.00 208.45 ? 89  LYS C CG  1 
ATOM   6444  C CD  . LYS C 3 66  ? 163.298 184.038 213.194 1.00 208.45 ? 89  LYS C CD  1 
ATOM   6445  C CE  . LYS C 3 66  ? 164.369 184.288 212.146 1.00 208.45 ? 89  LYS C CE  1 
ATOM   6446  N NZ  . LYS C 3 66  ? 163.887 185.192 211.066 1.00 208.45 ? 89  LYS C NZ  1 
ATOM   6447  N N   . ARG C 3 67  ? 161.488 182.668 217.958 1.00 204.40 ? 90  ARG C N   1 
ATOM   6448  C CA  . ARG C 3 67  ? 160.380 182.586 218.899 1.00 204.40 ? 90  ARG C CA  1 
ATOM   6449  C C   . ARG C 3 67  ? 159.083 182.289 218.157 1.00 204.40 ? 90  ARG C C   1 
ATOM   6450  O O   . ARG C 3 67  ? 158.786 182.912 217.133 1.00 204.40 ? 90  ARG C O   1 
ATOM   6451  C CB  . ARG C 3 67  ? 160.257 183.890 219.686 1.00 204.40 ? 90  ARG C CB  1 
ATOM   6452  C CG  . ARG C 3 67  ? 159.224 183.853 220.798 1.00 204.40 ? 90  ARG C CG  1 
ATOM   6453  C CD  . ARG C 3 67  ? 159.527 184.899 221.859 1.00 204.40 ? 90  ARG C CD  1 
ATOM   6454  N NE  . ARG C 3 67  ? 158.700 184.727 223.049 1.00 204.40 ? 90  ARG C NE  1 
ATOM   6455  C CZ  . ARG C 3 67  ? 158.882 185.392 224.186 1.00 204.40 ? 90  ARG C CZ  1 
ATOM   6456  N NH1 . ARG C 3 67  ? 159.865 186.275 224.289 1.00 204.40 ? 90  ARG C NH1 1 
ATOM   6457  N NH2 . ARG C 3 67  ? 158.081 185.173 225.220 1.00 204.40 ? 90  ARG C NH2 1 
ATOM   6458  N N   . GLU C 3 68  ? 158.324 181.317 218.665 1.00 201.02 ? 91  GLU C N   1 
ATOM   6459  C CA  . GLU C 3 68  ? 157.035 180.867 218.143 1.00 201.02 ? 91  GLU C CA  1 
ATOM   6460  C C   . GLU C 3 68  ? 157.166 180.162 216.796 1.00 201.02 ? 91  GLU C C   1 
ATOM   6461  O O   . GLU C 3 68  ? 156.164 179.656 216.276 1.00 201.02 ? 91  GLU C O   1 
ATOM   6462  C CB  . GLU C 3 68  ? 156.023 182.020 218.025 1.00 201.02 ? 91  GLU C CB  1 
ATOM   6463  C CG  . GLU C 3 68  ? 154.558 181.604 218.059 1.00 201.02 ? 91  GLU C CG  1 
ATOM   6464  C CD  . GLU C 3 68  ? 153.929 181.565 216.680 1.00 201.02 ? 91  GLU C CD  1 
ATOM   6465  O OE1 . GLU C 3 68  ? 154.376 182.331 215.800 1.00 201.02 ? 91  GLU C OE1 1 
ATOM   6466  O OE2 . GLU C 3 68  ? 152.990 180.768 216.474 1.00 201.02 ? 91  GLU C OE2 1 
ATOM   6467  N N   . GLU C 3 69  ? 158.365 180.086 216.224 1.00 192.23 ? 92  GLU C N   1 
ATOM   6468  C CA  . GLU C 3 69  ? 158.555 179.437 214.935 1.00 192.23 ? 92  GLU C CA  1 
ATOM   6469  C C   . GLU C 3 69  ? 158.542 177.923 215.104 1.00 192.23 ? 92  GLU C C   1 
ATOM   6470  O O   . GLU C 3 69  ? 159.241 177.378 215.964 1.00 192.23 ? 92  GLU C O   1 
ATOM   6471  C CB  . GLU C 3 69  ? 159.869 179.891 214.301 1.00 192.23 ? 92  GLU C CB  1 
ATOM   6472  C CG  . GLU C 3 69  ? 160.258 179.123 213.049 1.00 192.23 ? 92  GLU C CG  1 
ATOM   6473  C CD  . GLU C 3 69  ? 161.553 179.621 212.440 1.00 192.23 ? 92  GLU C CD  1 
ATOM   6474  O OE1 . GLU C 3 69  ? 161.880 180.812 212.627 1.00 192.23 ? 92  GLU C OE1 1 
ATOM   6475  O OE2 . GLU C 3 69  ? 162.246 178.823 211.775 1.00 192.23 ? 92  GLU C OE2 1 
ATOM   6476  N N   . ALA C 3 70  ? 157.746 177.245 214.281 1.00 160.10 ? 93  ALA C N   1 
ATOM   6477  C CA  . ALA C 3 70  ? 157.645 175.793 214.321 1.00 160.10 ? 93  ALA C CA  1 
ATOM   6478  C C   . ALA C 3 70  ? 158.702 175.179 213.414 1.00 160.10 ? 93  ALA C C   1 
ATOM   6479  O O   . ALA C 3 70  ? 158.882 175.618 212.273 1.00 160.10 ? 93  ALA C O   1 
ATOM   6480  C CB  . ALA C 3 70  ? 156.249 175.336 213.897 1.00 160.10 ? 93  ALA C CB  1 
ATOM   6481  N N   . VAL C 3 71  ? 159.395 174.166 213.922 1.00 132.60 ? 94  VAL C N   1 
ATOM   6482  C CA  . VAL C 3 71  ? 160.459 173.500 213.180 1.00 132.60 ? 94  VAL C CA  1 
ATOM   6483  C C   . VAL C 3 71  ? 159.864 172.333 212.405 1.00 132.60 ? 94  VAL C C   1 
ATOM   6484  O O   . VAL C 3 71  ? 159.155 171.493 212.973 1.00 132.60 ? 94  VAL C O   1 
ATOM   6485  C CB  . VAL C 3 71  ? 161.574 173.024 214.125 1.00 132.60 ? 94  VAL C CB  1 
ATOM   6486  C CG1 . VAL C 3 71  ? 162.723 172.424 213.330 1.00 132.60 ? 94  VAL C CG1 1 
ATOM   6487  C CG2 . VAL C 3 71  ? 162.061 174.175 214.992 1.00 132.60 ? 94  VAL C CG2 1 
ATOM   6488  N N   . ARG C 3 72  ? 160.151 172.279 211.108 1.00 114.01 ? 95  ARG C N   1 
ATOM   6489  C CA  . ARG C 3 72  ? 159.673 171.219 210.234 1.00 114.01 ? 95  ARG C CA  1 
ATOM   6490  C C   . ARG C 3 72  ? 160.841 170.347 209.795 1.00 114.01 ? 95  ARG C C   1 
ATOM   6491  O O   . ARG C 3 72  ? 161.915 170.855 209.457 1.00 114.01 ? 95  ARG C O   1 
ATOM   6492  C CB  . ARG C 3 72  ? 158.960 171.796 209.009 1.00 114.01 ? 95  ARG C CB  1 
ATOM   6493  C CG  . ARG C 3 72  ? 157.816 172.739 209.344 1.00 114.01 ? 95  ARG C CG  1 
ATOM   6494  C CD  . ARG C 3 72  ? 157.650 173.806 208.275 1.00 114.01 ? 95  ARG C CD  1 
ATOM   6495  N NE  . ARG C 3 72  ? 157.283 173.236 206.982 1.00 114.01 ? 95  ARG C NE  1 
ATOM   6496  C CZ  . ARG C 3 72  ? 156.048 173.231 206.491 1.00 114.01 ? 95  ARG C CZ  1 
ATOM   6497  N NH1 . ARG C 3 72  ? 155.054 173.768 207.186 1.00 114.01 ? 95  ARG C NH1 1 
ATOM   6498  N NH2 . ARG C 3 72  ? 155.806 172.690 205.305 1.00 114.01 ? 95  ARG C NH2 1 
ATOM   6499  N N   . TRP C 3 73  ? 160.626 169.033 209.802 1.00 90.54  ? 96  TRP C N   1 
ATOM   6500  C CA  . TRP C 3 73  ? 161.653 168.084 209.403 1.00 90.54  ? 96  TRP C CA  1 
ATOM   6501  C C   . TRP C 3 73  ? 160.988 166.891 208.734 1.00 90.54  ? 96  TRP C C   1 
ATOM   6502  O O   . TRP C 3 73  ? 159.829 166.573 209.011 1.00 90.54  ? 96  TRP C O   1 
ATOM   6503  C CB  . TRP C 3 73  ? 162.493 167.627 210.601 1.00 90.54  ? 96  TRP C CB  1 
ATOM   6504  C CG  . TRP C 3 73  ? 163.682 166.802 210.223 1.00 90.54  ? 96  TRP C CG  1 
ATOM   6505  C CD1 . TRP C 3 73  ? 164.826 167.240 209.623 1.00 90.54  ? 96  TRP C CD1 1 
ATOM   6506  C CD2 . TRP C 3 73  ? 163.847 165.394 210.421 1.00 90.54  ? 96  TRP C CD2 1 
ATOM   6507  N NE1 . TRP C 3 73  ? 165.693 166.192 209.434 1.00 90.54  ? 96  TRP C NE1 1 
ATOM   6508  C CE2 . TRP C 3 73  ? 165.116 165.047 209.916 1.00 90.54  ? 96  TRP C CE2 1 
ATOM   6509  C CE3 . TRP C 3 73  ? 163.046 164.392 210.977 1.00 90.54  ? 96  TRP C CE3 1 
ATOM   6510  C CZ2 . TRP C 3 73  ? 165.601 163.742 209.950 1.00 90.54  ? 96  TRP C CZ2 1 
ATOM   6511  C CZ3 . TRP C 3 73  ? 163.530 163.097 211.011 1.00 90.54  ? 96  TRP C CZ3 1 
ATOM   6512  C CH2 . TRP C 3 73  ? 164.795 162.784 210.500 1.00 90.54  ? 96  TRP C CH2 1 
ATOM   6513  N N   . ASN C 3 74  ? 161.735 166.233 207.850 1.00 81.59  ? 97  ASN C N   1 
ATOM   6514  C CA  . ASN C 3 74  ? 161.227 165.105 207.087 1.00 81.59  ? 97  ASN C CA  1 
ATOM   6515  C C   . ASN C 3 74  ? 162.219 163.952 207.142 1.00 81.59  ? 97  ASN C C   1 
ATOM   6516  O O   . ASN C 3 74  ? 163.420 164.152 207.340 1.00 81.59  ? 97  ASN C O   1 
ATOM   6517  C CB  . ASN C 3 74  ? 160.961 165.492 205.628 1.00 81.59  ? 97  ASN C CB  1 
ATOM   6518  C CG  . ASN C 3 74  ? 160.217 166.805 205.501 1.00 81.59  ? 97  ASN C CG  1 
ATOM   6519  O OD1 . ASN C 3 74  ? 159.185 167.011 206.139 1.00 81.59  ? 97  ASN C OD1 1 
ATOM   6520  N ND2 . ASN C 3 74  ? 160.740 167.704 204.676 1.00 81.59  ? 97  ASN C ND2 1 
ATOM   6521  N N   . TRP C 3 75  ? 161.698 162.740 206.964 1.00 68.70  ? 98  TRP C N   1 
ATOM   6522  C CA  . TRP C 3 75  ? 162.512 161.535 206.944 1.00 68.70  ? 98  TRP C CA  1 
ATOM   6523  C C   . TRP C 3 75  ? 161.909 160.542 205.962 1.00 68.70  ? 98  TRP C C   1 
ATOM   6524  O O   . TRP C 3 75  ? 160.688 160.459 205.812 1.00 68.70  ? 98  TRP C O   1 
ATOM   6525  C CB  . TRP C 3 75  ? 162.623 160.898 208.335 1.00 68.70  ? 98  TRP C CB  1 
ATOM   6526  C CG  . TRP C 3 75  ? 163.472 159.666 208.360 1.00 68.70  ? 98  TRP C CG  1 
ATOM   6527  C CD1 . TRP C 3 75  ? 164.829 159.604 208.239 1.00 68.70  ? 98  TRP C CD1 1 
ATOM   6528  C CD2 . TRP C 3 75  ? 163.021 158.315 208.513 1.00 68.70  ? 98  TRP C CD2 1 
ATOM   6529  N NE1 . TRP C 3 75  ? 165.252 158.299 208.308 1.00 68.70  ? 98  TRP C NE1 1 
ATOM   6530  C CE2 . TRP C 3 75  ? 164.161 157.488 208.475 1.00 68.70  ? 98  TRP C CE2 1 
ATOM   6531  C CE3 . TRP C 3 75  ? 161.765 157.725 208.678 1.00 68.70  ? 98  TRP C CE3 1 
ATOM   6532  C CZ2 . TRP C 3 75  ? 164.082 156.103 208.598 1.00 68.70  ? 98  TRP C CZ2 1 
ATOM   6533  C CZ3 . TRP C 3 75  ? 161.689 156.351 208.800 1.00 68.70  ? 98  TRP C CZ3 1 
ATOM   6534  C CH2 . TRP C 3 75  ? 162.840 155.555 208.759 1.00 68.70  ? 98  TRP C CH2 1 
ATOM   6535  N N   . THR C 3 76  ? 162.778 159.788 205.297 1.00 62.89  ? 99  THR C N   1 
ATOM   6536  C CA  . THR C 3 76  ? 162.372 158.816 204.294 1.00 62.89  ? 99  THR C CA  1 
ATOM   6537  C C   . THR C 3 76  ? 162.660 157.405 204.788 1.00 62.89  ? 99  THR C C   1 
ATOM   6538  O O   . THR C 3 76  ? 163.738 157.133 205.325 1.00 62.89  ? 99  THR C O   1 
ATOM   6539  C CB  . THR C 3 76  ? 163.097 159.060 202.967 1.00 62.89  ? 99  THR C CB  1 
ATOM   6540  O OG1 . THR C 3 76  ? 162.916 160.423 202.565 1.00 62.89  ? 99  THR C OG1 1 
ATOM   6541  C CG2 . THR C 3 76  ? 162.551 158.143 201.882 1.00 62.89  ? 99  THR C CG2 1 
ATOM   6542  N N   . SER C 3 77  ? 161.690 156.514 204.607 1.00 63.06  ? 100 SER C N   1 
ATOM   6543  C CA  . SER C 3 77  ? 161.827 155.111 204.964 1.00 63.06  ? 100 SER C CA  1 
ATOM   6544  C C   . SER C 3 77  ? 161.869 154.265 203.699 1.00 63.06  ? 100 SER C C   1 
ATOM   6545  O O   . SER C 3 77  ? 161.112 154.506 202.754 1.00 63.06  ? 100 SER C O   1 
ATOM   6546  C CB  . SER C 3 77  ? 160.673 154.653 205.859 1.00 63.06  ? 100 SER C CB  1 
ATOM   6547  O OG  . SER C 3 77  ? 160.508 153.248 205.796 1.00 63.06  ? 100 SER C OG  1 
ATOM   6548  N N   . ASP C 3 78  ? 162.758 153.270 203.686 1.00 63.70  ? 101 ASP C N   1 
ATOM   6549  C CA  . ASP C 3 78  ? 162.889 152.415 202.511 1.00 63.70  ? 101 ASP C CA  1 
ATOM   6550  C C   . ASP C 3 78  ? 161.694 151.479 202.377 1.00 63.70  ? 101 ASP C C   1 
ATOM   6551  O O   . ASP C 3 78  ? 161.102 151.361 201.298 1.00 63.70  ? 101 ASP C O   1 
ATOM   6552  C CB  . ASP C 3 78  ? 164.194 151.623 202.581 1.00 63.70  ? 101 ASP C CB  1 
ATOM   6553  C CG  . ASP C 3 78  ? 164.437 151.020 203.951 1.00 63.70  ? 101 ASP C CG  1 
ATOM   6554  O OD1 . ASP C 3 78  ? 163.983 151.612 204.952 1.00 63.70  ? 101 ASP C OD1 1 
ATOM   6555  O OD2 . ASP C 3 78  ? 165.083 149.954 204.025 1.00 63.70  ? 101 ASP C OD2 1 
ATOM   6556  N N   . ILE C 3 79  ? 161.324 150.808 203.462 1.00 56.44  ? 102 ILE C N   1 
ATOM   6557  C CA  . ILE C 3 79  ? 160.190 149.889 203.459 1.00 56.44  ? 102 ILE C CA  1 
ATOM   6558  C C   . ILE C 3 79  ? 158.902 150.702 203.518 1.00 56.44  ? 102 ILE C C   1 
ATOM   6559  O O   . ILE C 3 79  ? 158.899 151.813 204.068 1.00 56.44  ? 102 ILE C O   1 
ATOM   6560  C CB  . ILE C 3 79  ? 160.286 148.887 204.621 1.00 56.44  ? 102 ILE C CB  1 
ATOM   6561  C CG1 . ILE C 3 79  ? 160.307 149.620 205.962 1.00 56.44  ? 102 ILE C CG1 1 
ATOM   6562  C CG2 . ILE C 3 79  ? 161.525 148.018 204.473 1.00 56.44  ? 102 ILE C CG2 1 
ATOM   6563  C CD1 . ILE C 3 79  ? 160.233 148.698 207.150 1.00 56.44  ? 102 ILE C CD1 1 
ATOM   6564  N N   . PRO C 3 80  ? 157.802 150.210 202.948 1.00 54.61  ? 103 PRO C N   1 
ATOM   6565  C CA  . PRO C 3 80  ? 156.548 150.973 202.987 1.00 54.61  ? 103 PRO C CA  1 
ATOM   6566  C C   . PRO C 3 80  ? 156.074 151.200 204.415 1.00 54.61  ? 103 PRO C C   1 
ATOM   6567  O O   . PRO C 3 80  ? 156.255 150.355 205.293 1.00 54.61  ? 103 PRO C O   1 
ATOM   6568  C CB  . PRO C 3 80  ? 155.572 150.091 202.201 1.00 54.61  ? 103 PRO C CB  1 
ATOM   6569  C CG  . PRO C 3 80  ? 156.441 149.253 201.326 1.00 54.61  ? 103 PRO C CG  1 
ATOM   6570  C CD  . PRO C 3 80  ? 157.685 148.998 202.121 1.00 54.61  ? 103 PRO C CD  1 
ATOM   6571  N N   . LEU C 3 81  ? 155.458 152.363 204.638 1.00 63.13  ? 104 LEU C N   1 
ATOM   6572  C CA  . LEU C 3 81  ? 155.029 152.737 205.980 1.00 63.13  ? 104 LEU C CA  1 
ATOM   6573  C C   . LEU C 3 81  ? 153.804 151.960 206.443 1.00 63.13  ? 104 LEU C C   1 
ATOM   6574  O O   . LEU C 3 81  ? 153.592 151.832 207.653 1.00 63.13  ? 104 LEU C O   1 
ATOM   6575  C CB  . LEU C 3 81  ? 154.742 154.237 206.038 1.00 63.13  ? 104 LEU C CB  1 
ATOM   6576  C CG  . LEU C 3 81  ? 155.939 155.160 205.809 1.00 63.13  ? 104 LEU C CG  1 
ATOM   6577  C CD1 . LEU C 3 81  ? 155.511 156.617 205.870 1.00 63.13  ? 104 LEU C CD1 1 
ATOM   6578  C CD2 . LEU C 3 81  ? 157.034 154.877 206.825 1.00 63.13  ? 104 LEU C CD2 1 
ATOM   6579  N N   . GLU C 3 82  ? 152.998 151.438 205.517 1.00 67.94  ? 105 GLU C N   1 
ATOM   6580  C CA  . GLU C 3 82  ? 151.788 150.713 205.889 1.00 67.94  ? 105 GLU C CA  1 
ATOM   6581  C C   . GLU C 3 82  ? 152.068 149.314 206.421 1.00 67.94  ? 105 GLU C C   1 
ATOM   6582  O O   . GLU C 3 82  ? 151.113 148.577 206.691 1.00 67.94  ? 105 GLU C O   1 
ATOM   6583  C CB  . GLU C 3 82  ? 150.840 150.621 204.691 1.00 67.94  ? 105 GLU C CB  1 
ATOM   6584  C CG  . GLU C 3 82  ? 150.633 151.931 203.952 1.00 67.94  ? 105 GLU C CG  1 
ATOM   6585  C CD  . GLU C 3 82  ? 151.555 152.077 202.759 1.00 67.94  ? 105 GLU C CD  1 
ATOM   6586  O OE1 . GLU C 3 82  ? 152.471 151.242 202.610 1.00 67.94  ? 105 GLU C OE1 1 
ATOM   6587  O OE2 . GLU C 3 82  ? 151.363 153.025 201.969 1.00 67.94  ? 105 GLU C OE2 1 
ATOM   6588  N N   . CYS C 3 83  ? 153.333 148.927 206.580 1.00 64.31  ? 106 CYS C N   1 
ATOM   6589  C CA  . CYS C 3 83  ? 153.688 147.581 207.010 1.00 64.31  ? 106 CYS C CA  1 
ATOM   6590  C C   . CYS C 3 83  ? 154.100 147.515 208.476 1.00 64.31  ? 106 CYS C C   1 
ATOM   6591  O O   . CYS C 3 83  ? 153.734 146.568 209.177 1.00 64.31  ? 106 CYS C O   1 
ATOM   6592  C CB  . CYS C 3 83  ? 154.814 147.031 206.127 1.00 64.31  ? 106 CYS C CB  1 
ATOM   6593  S SG  . CYS C 3 83  ? 154.304 146.624 204.441 1.00 64.31  ? 106 CYS C SG  1 
ATOM   6594  N N   . VAL C 3 84  ? 154.855 148.500 208.959 1.00 62.72  ? 107 VAL C N   1 
ATOM   6595  C CA  . VAL C 3 84  ? 155.359 148.489 210.326 1.00 62.72  ? 107 VAL C CA  1 
ATOM   6596  C C   . VAL C 3 84  ? 155.330 149.907 210.882 1.00 62.72  ? 107 VAL C C   1 
ATOM   6597  O O   . VAL C 3 84  ? 155.426 150.889 210.141 1.00 62.72  ? 107 VAL C O   1 
ATOM   6598  C CB  . VAL C 3 84  ? 156.786 147.894 210.396 1.00 62.72  ? 107 VAL C CB  1 
ATOM   6599  C CG1 . VAL C 3 84  ? 157.778 148.819 209.722 1.00 62.72  ? 107 VAL C CG1 1 
ATOM   6600  C CG2 . VAL C 3 84  ? 157.194 147.599 211.835 1.00 62.72  ? 107 VAL C CG2 1 
ATOM   6601  N N   . LYS C 3 85  ? 155.179 150.006 212.200 1.00 72.01  ? 108 LYS C N   1 
ATOM   6602  C CA  . LYS C 3 85  ? 155.187 151.280 212.899 1.00 72.01  ? 108 LYS C CA  1 
ATOM   6603  C C   . LYS C 3 85  ? 156.606 151.645 213.334 1.00 72.01  ? 108 LYS C C   1 
ATOM   6604  O O   . LYS C 3 85  ? 157.536 150.840 213.259 1.00 72.01  ? 108 LYS C O   1 
ATOM   6605  C CB  . LYS C 3 85  ? 154.254 151.229 214.108 1.00 72.01  ? 108 LYS C CB  1 
ATOM   6606  C CG  . LYS C 3 85  ? 154.468 150.018 215.002 1.00 72.01  ? 108 LYS C CG  1 
ATOM   6607  C CD  . LYS C 3 85  ? 153.501 150.015 216.174 1.00 72.01  ? 108 LYS C CD  1 
ATOM   6608  C CE  . LYS C 3 85  ? 153.617 148.733 216.981 1.00 72.01  ? 108 LYS C CE  1 
ATOM   6609  N NZ  . LYS C 3 85  ? 155.003 148.514 217.477 1.00 72.01  ? 108 LYS C NZ  1 
ATOM   6610  N N   . HIS C 3 86  ? 156.765 152.886 213.795 1.00 68.17  ? 109 HIS C N   1 
ATOM   6611  C CA  . HIS C 3 86  ? 158.056 153.392 214.240 1.00 68.17  ? 109 HIS C CA  1 
ATOM   6612  C C   . HIS C 3 86  ? 157.863 154.198 215.519 1.00 68.17  ? 109 HIS C C   1 
ATOM   6613  O O   . HIS C 3 86  ? 156.742 154.381 216.003 1.00 68.17  ? 109 HIS C O   1 
ATOM   6614  C CB  . HIS C 3 86  ? 158.726 154.244 213.156 1.00 68.17  ? 109 HIS C CB  1 
ATOM   6615  C CG  . HIS C 3 86  ? 159.036 153.494 211.898 1.00 68.17  ? 109 HIS C CG  1 
ATOM   6616  N ND1 . HIS C 3 86  ? 158.073 153.165 210.969 1.00 68.17  ? 109 HIS C ND1 1 
ATOM   6617  C CD2 . HIS C 3 86  ? 160.206 153.013 211.414 1.00 68.17  ? 109 HIS C CD2 1 
ATOM   6618  C CE1 . HIS C 3 86  ? 158.635 152.512 209.968 1.00 68.17  ? 109 HIS C CE1 1 
ATOM   6619  N NE2 . HIS C 3 86  ? 159.928 152.406 210.213 1.00 68.17  ? 109 HIS C NE2 1 
ATOM   6620  N N   . PHE C 3 87  ? 158.976 154.680 216.070 1.00 76.90  ? 110 PHE C N   1 
ATOM   6621  C CA  . PHE C 3 87  ? 158.962 155.526 217.257 1.00 76.90  ? 110 PHE C CA  1 
ATOM   6622  C C   . PHE C 3 87  ? 160.088 156.541 217.135 1.00 76.90  ? 110 PHE C C   1 
ATOM   6623  O O   . PHE C 3 87  ? 161.227 156.168 216.839 1.00 76.90  ? 110 PHE C O   1 
ATOM   6624  C CB  . PHE C 3 87  ? 159.123 154.697 218.536 1.00 76.90  ? 110 PHE C CB  1 
ATOM   6625  C CG  . PHE C 3 87  ? 157.984 153.755 218.796 1.00 76.90  ? 110 PHE C CG  1 
ATOM   6626  C CD1 . PHE C 3 87  ? 156.837 154.193 219.436 1.00 76.90  ? 110 PHE C CD1 1 
ATOM   6627  C CD2 . PHE C 3 87  ? 158.060 152.429 218.402 1.00 76.90  ? 110 PHE C CD2 1 
ATOM   6628  C CE1 . PHE C 3 87  ? 155.787 153.328 219.677 1.00 76.90  ? 110 PHE C CE1 1 
ATOM   6629  C CE2 . PHE C 3 87  ? 157.013 151.560 218.640 1.00 76.90  ? 110 PHE C CE2 1 
ATOM   6630  C CZ  . PHE C 3 87  ? 155.876 152.010 219.279 1.00 76.90  ? 110 PHE C CZ  1 
ATOM   6631  N N   . ILE C 3 88  ? 159.771 157.814 217.363 1.00 72.17  ? 111 ILE C N   1 
ATOM   6632  C CA  . ILE C 3 88  ? 160.711 158.909 217.161 1.00 72.17  ? 111 ILE C CA  1 
ATOM   6633  C C   . ILE C 3 88  ? 160.741 159.780 218.408 1.00 72.17  ? 111 ILE C C   1 
ATOM   6634  O O   . ILE C 3 88  ? 159.694 160.082 218.992 1.00 72.17  ? 111 ILE C O   1 
ATOM   6635  C CB  . ILE C 3 88  ? 160.340 159.753 215.922 1.00 72.17  ? 111 ILE C CB  1 
ATOM   6636  C CG1 . ILE C 3 88  ? 160.223 158.865 214.682 1.00 72.17  ? 111 ILE C CG1 1 
ATOM   6637  C CG2 . ILE C 3 88  ? 161.364 160.853 215.692 1.00 72.17  ? 111 ILE C CG2 1 
ATOM   6638  C CD1 . ILE C 3 88  ? 159.829 159.615 213.430 1.00 72.17  ? 111 ILE C CD1 1 
ATOM   6639  N N   . ARG C 3 89  ? 161.944 160.184 218.816 1.00 88.76  ? 112 ARG C N   1 
ATOM   6640  C CA  . ARG C 3 89  ? 162.129 161.114 219.921 1.00 88.76  ? 112 ARG C CA  1 
ATOM   6641  C C   . ARG C 3 89  ? 163.294 162.038 219.598 1.00 88.76  ? 112 ARG C C   1 
ATOM   6642  O O   . ARG C 3 89  ? 164.286 161.612 219.000 1.00 88.76  ? 112 ARG C O   1 
ATOM   6643  C CB  . ARG C 3 89  ? 162.381 160.379 221.244 1.00 88.76  ? 112 ARG C CB  1 
ATOM   6644  C CG  . ARG C 3 89  ? 163.617 159.497 221.252 1.00 88.76  ? 112 ARG C CG  1 
ATOM   6645  C CD  . ARG C 3 89  ? 163.923 159.002 222.655 1.00 88.76  ? 112 ARG C CD  1 
ATOM   6646  N NE  . ARG C 3 89  ? 165.177 158.257 222.714 1.00 88.76  ? 112 ARG C NE  1 
ATOM   6647  C CZ  . ARG C 3 89  ? 165.713 157.788 223.836 1.00 88.76  ? 112 ARG C CZ  1 
ATOM   6648  N NH1 . ARG C 3 89  ? 165.104 157.986 224.997 1.00 88.76  ? 112 ARG C NH1 1 
ATOM   6649  N NH2 . ARG C 3 89  ? 166.857 157.120 223.798 1.00 88.76  ? 112 ARG C NH2 1 
ATOM   6650  N N   . ILE C 3 90  ? 163.165 163.306 219.988 1.00 105.06 ? 113 ILE C N   1 
ATOM   6651  C CA  . ILE C 3 90  ? 164.151 164.331 219.670 1.00 105.06 ? 113 ILE C CA  1 
ATOM   6652  C C   . ILE C 3 90  ? 164.521 165.086 220.938 1.00 105.06 ? 113 ILE C C   1 
ATOM   6653  O O   . ILE C 3 90  ? 163.684 165.313 221.817 1.00 105.06 ? 113 ILE C O   1 
ATOM   6654  C CB  . ILE C 3 90  ? 163.636 165.315 218.593 1.00 105.06 ? 113 ILE C CB  1 
ATOM   6655  C CG1 . ILE C 3 90  ? 162.946 164.566 217.452 1.00 105.06 ? 113 ILE C CG1 1 
ATOM   6656  C CG2 . ILE C 3 90  ? 164.775 166.163 218.048 1.00 105.06 ? 113 ILE C CG2 1 
ATOM   6657  C CD1 . ILE C 3 90  ? 162.408 165.472 216.368 1.00 105.06 ? 113 ILE C CD1 1 
ATOM   6658  N N   . ARG C 3 91  ? 165.791 165.476 221.028 1.00 126.42 ? 114 ARG C N   1 
ATOM   6659  C CA  . ARG C 3 91  ? 166.277 166.348 222.087 1.00 126.42 ? 114 ARG C CA  1 
ATOM   6660  C C   . ARG C 3 91  ? 167.078 167.482 221.464 1.00 126.42 ? 114 ARG C C   1 
ATOM   6661  O O   . ARG C 3 91  ? 167.619 167.356 220.362 1.00 126.42 ? 114 ARG C O   1 
ATOM   6662  C CB  . ARG C 3 91  ? 167.132 165.586 223.110 1.00 126.42 ? 114 ARG C CB  1 
ATOM   6663  C CG  . ARG C 3 91  ? 168.445 165.054 222.565 1.00 126.42 ? 114 ARG C CG  1 
ATOM   6664  C CD  . ARG C 3 91  ? 169.266 164.401 223.666 1.00 126.42 ? 114 ARG C CD  1 
ATOM   6665  N NE  . ARG C 3 91  ? 170.493 163.797 223.154 1.00 126.42 ? 114 ARG C NE  1 
ATOM   6666  C CZ  . ARG C 3 91  ? 171.334 163.077 223.889 1.00 126.42 ? 114 ARG C CZ  1 
ATOM   6667  N NH1 . ARG C 3 91  ? 171.083 162.867 225.174 1.00 126.42 ? 114 ARG C NH1 1 
ATOM   6668  N NH2 . ARG C 3 91  ? 172.426 162.566 223.339 1.00 126.42 ? 114 ARG C NH2 1 
ATOM   6669  N N   . ALA C 3 92  ? 167.149 168.598 222.181 1.00 153.79 ? 115 ALA C N   1 
ATOM   6670  C CA  . ALA C 3 92  ? 167.749 169.818 221.664 1.00 153.79 ? 115 ALA C CA  1 
ATOM   6671  C C   . ALA C 3 92  ? 169.134 170.050 222.260 1.00 153.79 ? 115 ALA C C   1 
ATOM   6672  O O   . ALA C 3 92  ? 169.527 169.441 223.258 1.00 153.79 ? 115 ALA C O   1 
ATOM   6673  C CB  . ALA C 3 92  ? 166.842 171.020 221.943 1.00 153.79 ? 115 ALA C CB  1 
ATOM   6674  N N   . LEU C 3 93  ? 169.876 170.954 221.623 1.00 175.97 ? 116 LEU C N   1 
ATOM   6675  C CA  . LEU C 3 93  ? 171.215 171.322 222.059 1.00 175.97 ? 116 LEU C CA  1 
ATOM   6676  C C   . LEU C 3 93  ? 171.572 172.664 221.438 1.00 175.97 ? 116 LEU C C   1 
ATOM   6677  O O   . LEU C 3 93  ? 171.248 172.917 220.275 1.00 175.97 ? 116 LEU C O   1 
ATOM   6678  C CB  . LEU C 3 93  ? 172.247 170.262 221.663 1.00 175.97 ? 116 LEU C CB  1 
ATOM   6679  C CG  . LEU C 3 93  ? 173.640 170.414 222.275 1.00 175.97 ? 116 LEU C CG  1 
ATOM   6680  C CD1 . LEU C 3 93  ? 173.646 169.938 223.718 1.00 175.97 ? 116 LEU C CD1 1 
ATOM   6681  C CD2 . LEU C 3 93  ? 174.678 169.666 221.453 1.00 175.97 ? 116 LEU C CD2 1 
ATOM   6682  N N   . VAL C 3 94  ? 172.241 173.514 222.213 1.00 209.15 ? 117 VAL C N   1 
ATOM   6683  C CA  . VAL C 3 94  ? 172.614 174.856 221.782 1.00 209.15 ? 117 VAL C CA  1 
ATOM   6684  C C   . VAL C 3 94  ? 174.120 174.904 221.558 1.00 209.15 ? 117 VAL C C   1 
ATOM   6685  O O   . VAL C 3 94  ? 174.896 174.354 222.349 1.00 209.15 ? 117 VAL C O   1 
ATOM   6686  C CB  . VAL C 3 94  ? 172.164 175.922 222.802 1.00 209.15 ? 117 VAL C CB  1 
ATOM   6687  C CG1 . VAL C 3 94  ? 172.757 175.645 224.179 1.00 209.15 ? 117 VAL C CG1 1 
ATOM   6688  C CG2 . VAL C 3 94  ? 172.535 177.318 222.321 1.00 209.15 ? 117 VAL C CG2 1 
ATOM   6689  N N   . ASP C 3 95  ? 174.529 175.545 220.462 1.00 230.96 ? 118 ASP C N   1 
ATOM   6690  C CA  . ASP C 3 95  ? 175.944 175.730 220.141 1.00 230.96 ? 118 ASP C CA  1 
ATOM   6691  C C   . ASP C 3 95  ? 176.347 177.142 220.556 1.00 230.96 ? 118 ASP C C   1 
ATOM   6692  O O   . ASP C 3 95  ? 176.493 178.049 219.737 1.00 230.96 ? 118 ASP C O   1 
ATOM   6693  C CB  . ASP C 3 95  ? 176.198 175.477 218.658 1.00 230.96 ? 118 ASP C CB  1 
ATOM   6694  C CG  . ASP C 3 95  ? 175.167 176.144 217.769 1.00 230.96 ? 118 ASP C CG  1 
ATOM   6695  O OD1 . ASP C 3 95  ? 174.186 176.699 218.308 1.00 230.96 ? 118 ASP C OD1 1 
ATOM   6696  O OD2 . ASP C 3 95  ? 175.337 176.114 216.532 1.00 230.96 ? 118 ASP C OD2 1 
ATOM   6697  N N   . ASP C 3 96  ? 176.531 177.321 221.862 1.00 264.40 ? 119 ASP C N   1 
ATOM   6698  C CA  . ASP C 3 96  ? 176.903 178.615 222.432 1.00 264.40 ? 119 ASP C CA  1 
ATOM   6699  C C   . ASP C 3 96  ? 178.394 178.573 222.751 1.00 264.40 ? 119 ASP C C   1 
ATOM   6700  O O   . ASP C 3 96  ? 178.803 178.259 223.869 1.00 264.40 ? 119 ASP C O   1 
ATOM   6701  C CB  . ASP C 3 96  ? 176.066 178.927 223.667 1.00 264.40 ? 119 ASP C CB  1 
ATOM   6702  C CG  . ASP C 3 96  ? 175.858 180.415 223.869 1.00 264.40 ? 119 ASP C CG  1 
ATOM   6703  O OD1 . ASP C 3 96  ? 176.258 181.198 222.982 1.00 264.40 ? 119 ASP C OD1 1 
ATOM   6704  O OD2 . ASP C 3 96  ? 175.294 180.802 224.914 1.00 264.40 ? 119 ASP C OD2 1 
ATOM   6705  N N   . THR C 3 97  ? 179.213 178.894 221.750 1.00 277.53 ? 120 THR C N   1 
ATOM   6706  C CA  . THR C 3 97  ? 180.661 178.917 221.913 1.00 277.53 ? 120 THR C CA  1 
ATOM   6707  C C   . THR C 3 97  ? 181.174 180.238 222.470 1.00 277.53 ? 120 THR C C   1 
ATOM   6708  O O   . THR C 3 97  ? 182.391 180.395 222.622 1.00 277.53 ? 120 THR C O   1 
ATOM   6709  C CB  . THR C 3 97  ? 181.348 178.625 220.576 1.00 277.53 ? 120 THR C CB  1 
ATOM   6710  O OG1 . THR C 3 97  ? 182.767 178.759 220.726 1.00 277.53 ? 120 THR C OG1 1 
ATOM   6711  C CG2 . THR C 3 97  ? 180.863 179.592 219.506 1.00 277.53 ? 120 THR C CG2 1 
ATOM   6712  N N   . LYS C 3 98  ? 180.286 181.185 222.775 1.00 278.39 ? 121 LYS C N   1 
ATOM   6713  C CA  . LYS C 3 98  ? 180.680 182.471 223.332 1.00 278.39 ? 121 LYS C CA  1 
ATOM   6714  C C   . LYS C 3 98  ? 180.304 182.643 224.795 1.00 278.39 ? 121 LYS C C   1 
ATOM   6715  O O   . LYS C 3 98  ? 180.899 183.487 225.472 1.00 278.39 ? 121 LYS C O   1 
ATOM   6716  C CB  . LYS C 3 98  ? 180.056 183.617 222.522 1.00 278.39 ? 121 LYS C CB  1 
ATOM   6717  C CG  . LYS C 3 98  ? 178.536 183.605 222.503 1.00 278.39 ? 121 LYS C CG  1 
ATOM   6718  C CD  . LYS C 3 98  ? 177.982 184.794 221.736 1.00 278.39 ? 121 LYS C CD  1 
ATOM   6719  C CE  . LYS C 3 98  ? 176.462 184.787 221.730 1.00 278.39 ? 121 LYS C CE  1 
ATOM   6720  N NZ  . LYS C 3 98  ? 175.905 185.952 220.989 1.00 278.39 ? 121 LYS C NZ  1 
ATOM   6721  N N   . SER C 3 99  ? 179.340 181.874 225.296 1.00 276.84 ? 122 SER C N   1 
ATOM   6722  C CA  . SER C 3 99  ? 178.920 181.963 226.686 1.00 276.84 ? 122 SER C CA  1 
ATOM   6723  C C   . SER C 3 99  ? 178.439 180.594 227.141 1.00 276.84 ? 122 SER C C   1 
ATOM   6724  O O   . SER C 3 99  ? 177.817 179.862 226.366 1.00 276.84 ? 122 SER C O   1 
ATOM   6725  C CB  . SER C 3 99  ? 177.813 183.008 226.871 1.00 276.84 ? 122 SER C CB  1 
ATOM   6726  O OG  . SER C 3 99  ? 176.833 182.899 225.853 1.00 276.84 ? 122 SER C OG  1 
ATOM   6727  N N   . LEU C 3 100 ? 178.725 180.264 228.403 1.00 270.96 ? 123 LEU C N   1 
ATOM   6728  C CA  . LEU C 3 100 ? 178.393 178.974 229.000 1.00 270.96 ? 123 LEU C CA  1 
ATOM   6729  C C   . LEU C 3 100 ? 178.910 177.832 228.133 1.00 270.96 ? 123 LEU C C   1 
ATOM   6730  O O   . LEU C 3 100 ? 178.118 177.137 227.484 1.00 270.96 ? 123 LEU C O   1 
ATOM   6731  C CB  . LEU C 3 100 ? 176.882 178.838 229.212 1.00 270.96 ? 123 LEU C CB  1 
ATOM   6732  C CG  . LEU C 3 100 ? 176.146 179.976 229.926 1.00 270.96 ? 123 LEU C CG  1 
ATOM   6733  C CD1 . LEU C 3 100 ? 175.529 180.952 228.933 1.00 270.96 ? 123 LEU C CD1 1 
ATOM   6734  C CD2 . LEU C 3 100 ? 175.084 179.420 230.864 1.00 270.96 ? 123 LEU C CD2 1 
ATOM   6735  N N   . PRO C 3 101 ? 180.228 177.605 228.092 1.00 263.30 ? 124 PRO C N   1 
ATOM   6736  C CA  . PRO C 3 101 ? 180.766 176.543 227.232 1.00 263.30 ? 124 PRO C CA  1 
ATOM   6737  C C   . PRO C 3 101 ? 180.541 175.149 227.799 1.00 263.30 ? 124 PRO C C   1 
ATOM   6738  O O   . PRO C 3 101 ? 181.490 174.372 227.945 1.00 263.30 ? 124 PRO C O   1 
ATOM   6739  C CB  . PRO C 3 101 ? 182.259 176.882 227.159 1.00 263.30 ? 124 PRO C CB  1 
ATOM   6740  C CG  . PRO C 3 101 ? 182.540 177.550 228.462 1.00 263.30 ? 124 PRO C CG  1 
ATOM   6741  C CD  . PRO C 3 101 ? 181.289 178.312 228.831 1.00 263.30 ? 124 PRO C CD  1 
ATOM   6742  N N   . GLN C 3 102 ? 179.290 174.822 228.121 1.00 237.51 ? 125 GLN C N   1 
ATOM   6743  C CA  . GLN C 3 102 ? 178.913 173.508 228.644 1.00 237.51 ? 125 GLN C CA  1 
ATOM   6744  C C   . GLN C 3 102 ? 177.729 173.012 227.819 1.00 237.51 ? 125 GLN C C   1 
ATOM   6745  O O   . GLN C 3 102 ? 176.570 173.248 228.172 1.00 237.51 ? 125 GLN C O   1 
ATOM   6746  C CB  . GLN C 3 102 ? 178.581 173.579 230.132 1.00 237.51 ? 125 GLN C CB  1 
ATOM   6747  C CG  . GLN C 3 102 ? 178.361 172.223 230.782 1.00 237.51 ? 125 GLN C CG  1 
ATOM   6748  C CD  . GLN C 3 102 ? 178.153 172.322 232.280 1.00 237.51 ? 125 GLN C CD  1 
ATOM   6749  O OE1 . GLN C 3 102 ? 178.118 173.417 232.842 1.00 237.51 ? 125 GLN C OE1 1 
ATOM   6750  N NE2 . GLN C 3 102 ? 178.015 171.176 232.935 1.00 237.51 ? 125 GLN C NE2 1 
ATOM   6751  N N   . SER C 3 103 ? 178.025 172.323 226.719 1.00 206.71 ? 126 SER C N   1 
ATOM   6752  C CA  . SER C 3 103 ? 176.995 171.811 225.816 1.00 206.71 ? 126 SER C CA  1 
ATOM   6753  C C   . SER C 3 103 ? 176.476 170.492 226.375 1.00 206.71 ? 126 SER C C   1 
ATOM   6754  O O   . SER C 3 103 ? 177.017 169.418 226.106 1.00 206.71 ? 126 SER C O   1 
ATOM   6755  C CB  . SER C 3 103 ? 177.552 171.643 224.408 1.00 206.71 ? 126 SER C CB  1 
ATOM   6756  O OG  . SER C 3 103 ? 176.509 171.591 223.450 1.00 206.71 ? 126 SER C OG  1 
ATOM   6757  N N   . SER C 3 104 ? 175.409 170.576 227.163 1.00 179.52 ? 127 SER C N   1 
ATOM   6758  C CA  . SER C 3 104 ? 174.784 169.413 227.774 1.00 179.52 ? 127 SER C CA  1 
ATOM   6759  C C   . SER C 3 104 ? 173.440 169.140 227.112 1.00 179.52 ? 127 SER C C   1 
ATOM   6760  O O   . SER C 3 104 ? 172.645 170.060 226.897 1.00 179.52 ? 127 SER C O   1 
ATOM   6761  C CB  . SER C 3 104 ? 174.593 169.617 229.280 1.00 179.52 ? 127 SER C CB  1 
ATOM   6762  O OG  . SER C 3 104 ? 173.692 168.662 229.813 1.00 179.52 ? 127 SER C OG  1 
ATOM   6763  N N   . TRP C 3 105 ? 173.194 167.874 226.792 1.00 152.02 ? 128 TRP C N   1 
ATOM   6764  C CA  . TRP C 3 105 ? 171.948 167.494 226.144 1.00 152.02 ? 128 TRP C CA  1 
ATOM   6765  C C   . TRP C 3 105 ? 170.786 167.552 227.129 1.00 152.02 ? 128 TRP C C   1 
ATOM   6766  O O   . TRP C 3 105 ? 170.949 167.337 228.333 1.00 152.02 ? 128 TRP C O   1 
ATOM   6767  C CB  . TRP C 3 105 ? 172.059 166.088 225.554 1.00 152.02 ? 128 TRP C CB  1 
ATOM   6768  C CG  . TRP C 3 105 ? 173.074 165.969 224.459 1.00 152.02 ? 128 TRP C CG  1 
ATOM   6769  C CD1 . TRP C 3 105 ? 174.375 165.579 224.588 1.00 152.02 ? 128 TRP C CD1 1 
ATOM   6770  C CD2 . TRP C 3 105 ? 172.871 166.236 223.066 1.00 152.02 ? 128 TRP C CD2 1 
ATOM   6771  N NE1 . TRP C 3 105 ? 174.996 165.589 223.362 1.00 152.02 ? 128 TRP C NE1 1 
ATOM   6772  C CE2 . TRP C 3 105 ? 174.094 165.989 222.411 1.00 152.02 ? 128 TRP C CE2 1 
ATOM   6773  C CE3 . TRP C 3 105 ? 171.775 166.662 222.310 1.00 152.02 ? 128 TRP C CE3 1 
ATOM   6774  C CZ2 . TRP C 3 105 ? 174.251 166.152 221.037 1.00 152.02 ? 128 TRP C CZ2 1 
ATOM   6775  C CZ3 . TRP C 3 105 ? 171.933 166.823 220.946 1.00 152.02 ? 128 TRP C CZ3 1 
ATOM   6776  C CH2 . TRP C 3 105 ? 173.161 166.569 220.323 1.00 152.02 ? 128 TRP C CH2 1 
ATOM   6777  N N   . GLY C 3 106 ? 169.598 167.848 226.601 1.00 152.34 ? 129 GLY C N   1 
ATOM   6778  C CA  . GLY C 3 106 ? 168.398 167.907 227.406 1.00 152.34 ? 129 GLY C CA  1 
ATOM   6779  C C   . GLY C 3 106 ? 167.720 166.554 227.537 1.00 152.34 ? 129 GLY C C   1 
ATOM   6780  O O   . GLY C 3 106 ? 168.214 165.524 227.080 1.00 152.34 ? 129 GLY C O   1 
ATOM   6781  N N   . ASN C 3 107 ? 166.557 166.573 228.181 1.00 144.95 ? 130 ASN C N   1 
ATOM   6782  C CA  . ASN C 3 107 ? 165.789 165.352 228.376 1.00 144.95 ? 130 ASN C CA  1 
ATOM   6783  C C   . ASN C 3 107 ? 165.175 164.885 227.062 1.00 144.95 ? 130 ASN C C   1 
ATOM   6784  O O   . ASN C 3 107 ? 164.854 165.684 226.178 1.00 144.95 ? 130 ASN C O   1 
ATOM   6785  C CB  . ASN C 3 107 ? 164.690 165.573 229.415 1.00 144.95 ? 130 ASN C CB  1 
ATOM   6786  C CG  . ASN C 3 107 ? 165.240 165.978 230.767 1.00 144.95 ? 130 ASN C CG  1 
ATOM   6787  O OD1 . ASN C 3 107 ? 165.445 167.162 231.037 1.00 144.95 ? 130 ASN C OD1 1 
ATOM   6788  N ND2 . ASN C 3 107 ? 165.480 164.996 231.627 1.00 144.95 ? 130 ASN C ND2 1 
ATOM   6789  N N   . TRP C 3 108 ? 165.013 163.571 226.940 1.00 110.05 ? 131 TRP C N   1 
ATOM   6790  C CA  . TRP C 3 108 ? 164.414 162.990 225.747 1.00 110.05 ? 131 TRP C CA  1 
ATOM   6791  C C   . TRP C 3 108 ? 162.904 163.181 225.765 1.00 110.05 ? 131 TRP C C   1 
ATOM   6792  O O   . TRP C 3 108 ? 162.267 163.127 226.821 1.00 110.05 ? 131 TRP C O   1 
ATOM   6793  C CB  . TRP C 3 108 ? 164.752 161.503 225.648 1.00 110.05 ? 131 TRP C CB  1 
ATOM   6794  C CG  . TRP C 3 108 ? 166.140 161.228 225.153 1.00 110.05 ? 131 TRP C CG  1 
ATOM   6795  C CD1 . TRP C 3 108 ? 167.194 160.764 225.885 1.00 110.05 ? 131 TRP C CD1 1 
ATOM   6796  C CD2 . TRP C 3 108 ? 166.625 161.400 223.816 1.00 110.05 ? 131 TRP C CD2 1 
ATOM   6797  N NE1 . TRP C 3 108 ? 168.304 160.635 225.087 1.00 110.05 ? 131 TRP C NE1 1 
ATOM   6798  C CE2 . TRP C 3 108 ? 167.981 161.020 223.812 1.00 110.05 ? 131 TRP C CE2 1 
ATOM   6799  C CE3 . TRP C 3 108 ? 166.044 161.839 222.623 1.00 110.05 ? 131 TRP C CE3 1 
ATOM   6800  C CZ2 . TRP C 3 108 ? 168.765 161.064 222.662 1.00 110.05 ? 131 TRP C CZ2 1 
ATOM   6801  C CZ3 . TRP C 3 108 ? 166.824 161.882 221.482 1.00 110.05 ? 131 TRP C CZ3 1 
ATOM   6802  C CH2 . TRP C 3 108 ? 168.170 161.498 221.510 1.00 110.05 ? 131 TRP C CH2 1 
ATOM   6803  N N   . SER C 3 109 ? 162.333 163.404 224.585 1.00 98.00  ? 132 SER C N   1 
ATOM   6804  C CA  . SER C 3 109 ? 160.898 163.595 224.465 1.00 98.00  ? 132 SER C CA  1 
ATOM   6805  C C   . SER C 3 109 ? 160.170 162.254 224.541 1.00 98.00  ? 132 SER C C   1 
ATOM   6806  O O   . SER C 3 109 ? 160.779 161.183 224.602 1.00 98.00  ? 132 SER C O   1 
ATOM   6807  C CB  . SER C 3 109 ? 160.561 164.310 223.157 1.00 98.00  ? 132 SER C CB  1 
ATOM   6808  O OG  . SER C 3 109 ? 160.819 163.477 222.041 1.00 98.00  ? 132 SER C OG  1 
ATOM   6809  N N   . SER C 3 110 ? 158.842 162.326 224.540 1.00 95.78  ? 133 SER C N   1 
ATOM   6810  C CA  . SER C 3 110 ? 158.027 161.122 224.585 1.00 95.78  ? 133 SER C CA  1 
ATOM   6811  C C   . SER C 3 110 ? 158.051 160.405 223.240 1.00 95.78  ? 133 SER C C   1 
ATOM   6812  O O   . SER C 3 110 ? 158.166 161.025 222.179 1.00 95.78  ? 133 SER C O   1 
ATOM   6813  C CB  . SER C 3 110 ? 156.588 161.465 224.969 1.00 95.78  ? 133 SER C CB  1 
ATOM   6814  O OG  . SER C 3 110 ? 155.823 161.805 223.826 1.00 95.78  ? 133 SER C OG  1 
ATOM   6815  N N   . TRP C 3 111 ? 157.937 159.081 223.293 1.00 88.38  ? 134 TRP C N   1 
ATOM   6816  C CA  . TRP C 3 111 ? 157.950 158.254 222.088 1.00 88.38  ? 134 TRP C CA  1 
ATOM   6817  C C   . TRP C 3 111 ? 156.631 158.435 221.348 1.00 88.38  ? 134 TRP C C   1 
ATOM   6818  O O   . TRP C 3 111 ? 155.620 157.822 221.695 1.00 88.38  ? 134 TRP C O   1 
ATOM   6819  C CB  . TRP C 3 111 ? 158.180 156.792 222.451 1.00 88.38  ? 134 TRP C CB  1 
ATOM   6820  C CG  . TRP C 3 111 ? 159.477 156.543 223.154 1.00 88.38  ? 134 TRP C CG  1 
ATOM   6821  C CD1 . TRP C 3 111 ? 159.711 156.623 224.496 1.00 88.38  ? 134 TRP C CD1 1 
ATOM   6822  C CD2 . TRP C 3 111 ? 160.721 156.168 222.552 1.00 88.38  ? 134 TRP C CD2 1 
ATOM   6823  N NE1 . TRP C 3 111 ? 161.024 156.323 224.766 1.00 88.38  ? 134 TRP C NE1 1 
ATOM   6824  C CE2 . TRP C 3 111 ? 161.665 156.039 223.590 1.00 88.38  ? 134 TRP C CE2 1 
ATOM   6825  C CE3 . TRP C 3 111 ? 161.129 155.928 221.236 1.00 88.38  ? 134 TRP C CE3 1 
ATOM   6826  C CZ2 . TRP C 3 111 ? 162.991 155.682 223.353 1.00 88.38  ? 134 TRP C CZ2 1 
ATOM   6827  C CZ3 . TRP C 3 111 ? 162.445 155.575 221.004 1.00 88.38  ? 134 TRP C CZ3 1 
ATOM   6828  C CH2 . TRP C 3 111 ? 163.360 155.456 222.056 1.00 88.38  ? 134 TRP C CH2 1 
ATOM   6829  N N   . LYS C 3 112 ? 156.638 159.278 220.319 1.00 80.43  ? 135 LYS C N   1 
ATOM   6830  C CA  . LYS C 3 112 ? 155.445 159.517 219.513 1.00 80.43  ? 135 LYS C CA  1 
ATOM   6831  C C   . LYS C 3 112 ? 155.270 158.358 218.541 1.00 80.43  ? 135 LYS C C   1 
ATOM   6832  O O   . LYS C 3 112 ? 156.099 158.156 217.648 1.00 80.43  ? 135 LYS C O   1 
ATOM   6833  C CB  . LYS C 3 112 ? 155.556 160.847 218.774 1.00 80.43  ? 135 LYS C CB  1 
ATOM   6834  C CG  . LYS C 3 112 ? 155.277 162.061 219.644 1.00 80.43  ? 135 LYS C CG  1 
ATOM   6835  C CD  . LYS C 3 112 ? 153.829 162.089 220.103 1.00 80.43  ? 135 LYS C CD  1 
ATOM   6836  C CE  . LYS C 3 112 ? 153.531 163.338 220.915 1.00 80.43  ? 135 LYS C CE  1 
ATOM   6837  N NZ  . LYS C 3 112 ? 152.108 163.392 221.350 1.00 80.43  ? 135 LYS C NZ  1 
ATOM   6838  N N   . GLU C 3 113 ? 154.193 157.597 218.712 1.00 81.56  ? 136 GLU C N   1 
ATOM   6839  C CA  . GLU C 3 113 ? 153.951 156.429 217.875 1.00 81.56  ? 136 GLU C CA  1 
ATOM   6840  C C   . GLU C 3 113 ? 153.612 156.862 216.454 1.00 81.56  ? 136 GLU C C   1 
ATOM   6841  O O   . GLU C 3 113 ? 152.659 157.618 216.237 1.00 81.56  ? 136 GLU C O   1 
ATOM   6842  C CB  . GLU C 3 113 ? 152.824 155.584 218.461 1.00 81.56  ? 136 GLU C CB  1 
ATOM   6843  C CG  . GLU C 3 113 ? 152.416 154.410 217.587 1.00 81.56  ? 136 GLU C CG  1 
ATOM   6844  C CD  . GLU C 3 113 ? 151.281 153.604 218.185 1.00 81.56  ? 136 GLU C CD  1 
ATOM   6845  O OE1 . GLU C 3 113 ? 150.875 153.903 219.327 1.00 81.56  ? 136 GLU C OE1 1 
ATOM   6846  O OE2 . GLU C 3 113 ? 150.794 152.671 217.512 1.00 81.56  ? 136 GLU C OE2 1 
ATOM   6847  N N   . VAL C 3 114 ? 154.391 156.384 215.490 1.00 73.86  ? 137 VAL C N   1 
ATOM   6848  C CA  . VAL C 3 114 ? 154.143 156.625 214.075 1.00 73.86  ? 137 VAL C CA  1 
ATOM   6849  C C   . VAL C 3 114 ? 153.546 155.339 213.515 1.00 73.86  ? 137 VAL C C   1 
ATOM   6850  O O   . VAL C 3 114 ? 154.264 154.376 213.234 1.00 73.86  ? 137 VAL C O   1 
ATOM   6851  C CB  . VAL C 3 114 ? 155.420 157.032 213.336 1.00 73.86  ? 137 VAL C CB  1 
ATOM   6852  C CG1 . VAL C 3 114 ? 155.161 157.133 211.840 1.00 73.86  ? 137 VAL C CG1 1 
ATOM   6853  C CG2 . VAL C 3 114 ? 155.948 158.350 213.881 1.00 73.86  ? 137 VAL C CG2 1 
ATOM   6854  N N   . ASN C 3 115 ? 152.226 155.318 213.354 1.00 78.20  ? 138 ASN C N   1 
ATOM   6855  C CA  . ASN C 3 115 ? 151.502 154.128 212.928 1.00 78.20  ? 138 ASN C CA  1 
ATOM   6856  C C   . ASN C 3 115 ? 150.817 154.398 211.597 1.00 78.20  ? 138 ASN C C   1 
ATOM   6857  O O   . ASN C 3 115 ? 150.149 155.424 211.434 1.00 78.20  ? 138 ASN C O   1 
ATOM   6858  C CB  . ASN C 3 115 ? 150.471 153.708 213.980 1.00 78.20  ? 138 ASN C CB  1 
ATOM   6859  C CG  . ASN C 3 115 ? 150.082 152.248 213.865 1.00 78.20  ? 138 ASN C CG  1 
ATOM   6860  O OD1 . ASN C 3 115 ? 150.192 151.646 212.797 1.00 78.20  ? 138 ASN C OD1 1 
ATOM   6861  N ND2 . ASN C 3 115 ? 149.623 151.671 214.969 1.00 78.20  ? 138 ASN C ND2 1 
ATOM   6862  N N   . ALA C 3 116 ? 150.985 153.473 210.649 1.00 71.44  ? 139 ALA C N   1 
ATOM   6863  C CA  . ALA C 3 116 ? 150.356 153.609 209.341 1.00 71.44  ? 139 ALA C CA  1 
ATOM   6864  C C   . ALA C 3 116 ? 149.757 152.302 208.836 1.00 71.44  ? 139 ALA C C   1 
ATOM   6865  O O   . ALA C 3 116 ? 149.347 152.239 207.671 1.00 71.44  ? 139 ALA C O   1 
ATOM   6866  C CB  . ALA C 3 116 ? 151.358 154.148 208.315 1.00 71.44  ? 139 ALA C CB  1 
ATOM   6867  N N   . LYS C 3 117 ? 149.698 151.260 209.664 1.00 72.66  ? 140 LYS C N   1 
ATOM   6868  C CA  . LYS C 3 117 ? 149.083 149.998 209.265 1.00 72.66  ? 140 LYS C CA  1 
ATOM   6869  C C   . LYS C 3 117 ? 147.580 150.200 209.119 1.00 72.66  ? 140 LYS C C   1 
ATOM   6870  O O   . LYS C 3 117 ? 146.877 150.422 210.110 1.00 72.66  ? 140 LYS C O   1 
ATOM   6871  C CB  . LYS C 3 117 ? 149.393 148.913 210.291 1.00 72.66  ? 140 LYS C CB  1 
ATOM   6872  C CG  . LYS C 3 117 ? 150.867 148.789 210.634 1.00 72.66  ? 140 LYS C CG  1 
ATOM   6873  C CD  . LYS C 3 117 ? 151.098 147.734 211.702 1.00 72.66  ? 140 LYS C CD  1 
ATOM   6874  C CE  . LYS C 3 117 ? 150.664 146.360 211.221 1.00 72.66  ? 140 LYS C CE  1 
ATOM   6875  N NZ  . LYS C 3 117 ? 150.934 145.307 212.238 1.00 72.66  ? 140 LYS C NZ  1 
ATOM   6876  N N   . VAL C 3 118 ? 147.083 150.126 207.886 1.00 86.69  ? 141 VAL C N   1 
ATOM   6877  C CA  . VAL C 3 118 ? 145.688 150.445 207.606 1.00 86.69  ? 141 VAL C CA  1 
ATOM   6878  C C   . VAL C 3 118 ? 144.765 149.346 208.122 1.00 86.69  ? 141 VAL C C   1 
ATOM   6879  O O   . VAL C 3 118 ? 143.965 149.579 209.035 1.00 86.69  ? 141 VAL C O   1 
ATOM   6880  C CB  . VAL C 3 118 ? 145.475 150.707 206.102 1.00 86.69  ? 141 VAL C CB  1 
ATOM   6881  C CG1 . VAL C 3 118 ? 145.961 152.100 205.743 1.00 86.69  ? 141 VAL C CG1 1 
ATOM   6882  C CG2 . VAL C 3 118 ? 146.223 149.682 205.259 1.00 86.69  ? 141 VAL C CG2 1 
ATOM   6883  N N   . SER C 3 119 ? 144.883 148.142 207.566 1.00 98.21  ? 142 SER C N   1 
ATOM   6884  C CA  . SER C 3 119 ? 144.006 147.028 207.910 1.00 98.21  ? 142 SER C CA  1 
ATOM   6885  C C   . SER C 3 119 ? 144.492 145.791 207.170 1.00 98.21  ? 142 SER C C   1 
ATOM   6886  O O   . SER C 3 119 ? 145.416 145.853 206.354 1.00 98.21  ? 142 SER C O   1 
ATOM   6887  C CB  . SER C 3 119 ? 142.543 147.322 207.561 1.00 98.21  ? 142 SER C CB  1 
ATOM   6888  O OG  . SER C 3 119 ? 141.799 146.122 207.437 1.00 98.21  ? 142 SER C OG  1 
ATOM   6889  N N   . VAL C 3 120 ? 143.852 144.663 207.466 1.00 96.79  ? 143 VAL C N   1 
ATOM   6890  C CA  . VAL C 3 120 ? 144.155 143.402 206.799 1.00 96.79  ? 143 VAL C CA  1 
ATOM   6891  C C   . VAL C 3 120 ? 142.956 142.480 206.969 1.00 96.79  ? 143 VAL C C   1 
ATOM   6892  O O   . VAL C 3 120 ? 142.349 142.418 208.042 1.00 96.79  ? 143 VAL C O   1 
ATOM   6893  C CB  . VAL C 3 120 ? 145.456 142.772 207.352 1.00 96.79  ? 143 VAL C CB  1 
ATOM   6894  C CG1 . VAL C 3 120 ? 145.362 142.566 208.858 1.00 96.79  ? 143 VAL C CG1 1 
ATOM   6895  C CG2 . VAL C 3 120 ? 145.763 141.463 206.642 1.00 96.79  ? 143 VAL C CG2 1 
ATOM   6896  N N   . GLU C 3 121 ? 142.607 141.777 205.894 1.00 107.39 ? 144 GLU C N   1 
ATOM   6897  C CA  . GLU C 3 121 ? 141.497 140.839 205.976 1.00 107.39 ? 144 GLU C CA  1 
ATOM   6898  C C   . GLU C 3 121 ? 142.009 139.424 206.207 1.00 107.39 ? 144 GLU C C   1 
ATOM   6899  O O   . GLU C 3 121 ? 143.068 139.054 205.687 1.00 107.39 ? 144 GLU C O   1 
ATOM   6900  C CB  . GLU C 3 121 ? 140.660 140.872 204.696 1.00 107.39 ? 144 GLU C CB  1 
ATOM   6901  C CG  . GLU C 3 121 ? 139.868 142.155 204.503 1.00 107.39 ? 144 GLU C CG  1 
ATOM   6902  C CD  . GLU C 3 121 ? 140.673 143.240 203.815 1.00 107.39 ? 144 GLU C CD  1 
ATOM   6903  O OE1 . GLU C 3 121 ? 141.832 142.971 203.434 1.00 107.39 ? 144 GLU C OE1 1 
ATOM   6904  O OE2 . GLU C 3 121 ? 140.148 144.361 203.655 1.00 107.39 ? 144 GLU C OE2 1 
ATOM   6905  N N   . PRO C 3 122 ? 141.282 138.617 206.984 1.00 104.86 ? 145 PRO C N   1 
ATOM   6906  C CA  . PRO C 3 122 ? 141.751 137.249 207.262 1.00 104.86 ? 145 PRO C CA  1 
ATOM   6907  C C   . PRO C 3 122 ? 141.832 136.365 206.030 1.00 104.86 ? 145 PRO C C   1 
ATOM   6908  O O   . PRO C 3 122 ? 142.557 135.363 206.055 1.00 104.86 ? 145 PRO C O   1 
ATOM   6909  C CB  . PRO C 3 122 ? 140.715 136.718 208.263 1.00 104.86 ? 145 PRO C CB  1 
ATOM   6910  C CG  . PRO C 3 122 ? 140.068 137.940 208.838 1.00 104.86 ? 145 PRO C CG  1 
ATOM   6911  C CD  . PRO C 3 122 ? 140.058 138.945 207.731 1.00 104.86 ? 145 PRO C CD  1 
ATOM   6912  N N   . ASP C 3 123 ? 141.114 136.696 204.955 1.00 103.84 ? 146 ASP C N   1 
ATOM   6913  C CA  . ASP C 3 123 ? 141.115 135.889 203.739 1.00 103.84 ? 146 ASP C CA  1 
ATOM   6914  C C   . ASP C 3 123 ? 141.658 136.655 202.538 1.00 103.84 ? 146 ASP C C   1 
ATOM   6915  O O   . ASP C 3 123 ? 141.422 136.253 201.394 1.00 103.84 ? 146 ASP C O   1 
ATOM   6916  C CB  . ASP C 3 123 ? 139.706 135.371 203.443 1.00 103.84 ? 146 ASP C CB  1 
ATOM   6917  C CG  . ASP C 3 123 ? 138.686 136.488 203.339 1.00 103.84 ? 146 ASP C CG  1 
ATOM   6918  O OD1 . ASP C 3 123 ? 138.860 137.518 204.022 1.00 103.84 ? 146 ASP C OD1 1 
ATOM   6919  O OD2 . ASP C 3 123 ? 137.711 136.335 202.574 1.00 103.84 ? 146 ASP C OD2 1 
ATOM   6920  N N   . LYS C 3 124 ? 142.380 137.748 202.770 1.00 89.56  ? 147 LYS C N   1 
ATOM   6921  C CA  . LYS C 3 124 ? 142.941 138.562 201.701 1.00 89.56  ? 147 LYS C CA  1 
ATOM   6922  C C   . LYS C 3 124 ? 144.395 138.884 202.024 1.00 89.56  ? 147 LYS C C   1 
ATOM   6923  O O   . LYS C 3 124 ? 144.930 138.487 203.063 1.00 89.56  ? 147 LYS C O   1 
ATOM   6924  C CB  . LYS C 3 124 ? 142.127 139.846 201.496 1.00 89.56  ? 147 LYS C CB  1 
ATOM   6925  C CG  . LYS C 3 124 ? 140.745 139.619 200.907 1.00 89.56  ? 147 LYS C CG  1 
ATOM   6926  C CD  . LYS C 3 124 ? 140.051 140.937 200.607 1.00 89.56  ? 147 LYS C CD  1 
ATOM   6927  C CE  . LYS C 3 124 ? 138.691 140.712 199.968 1.00 89.56  ? 147 LYS C CE  1 
ATOM   6928  N NZ  . LYS C 3 124 ? 138.006 141.997 199.655 1.00 89.56  ? 147 LYS C NZ  1 
ATOM   6929  N N   . SER C 3 125 ? 145.038 139.616 201.116 1.00 71.24  ? 148 SER C N   1 
ATOM   6930  C CA  . SER C 3 125 ? 146.432 139.996 201.280 1.00 71.24  ? 148 SER C CA  1 
ATOM   6931  C C   . SER C 3 125 ? 146.689 141.285 200.515 1.00 71.24  ? 148 SER C C   1 
ATOM   6932  O O   . SER C 3 125 ? 146.027 141.573 199.514 1.00 71.24  ? 148 SER C O   1 
ATOM   6933  C CB  . SER C 3 125 ? 147.378 138.892 200.795 1.00 71.24  ? 148 SER C CB  1 
ATOM   6934  O OG  . SER C 3 125 ? 147.308 138.747 199.388 1.00 71.24  ? 148 SER C OG  1 
ATOM   6935  N N   . LEU C 3 126 ? 147.659 142.058 200.997 1.00 62.41  ? 149 LEU C N   1 
ATOM   6936  C CA  . LEU C 3 126 ? 148.031 143.325 200.391 1.00 62.41  ? 149 LEU C CA  1 
ATOM   6937  C C   . LEU C 3 126 ? 149.518 143.326 200.062 1.00 62.41  ? 149 LEU C C   1 
ATOM   6938  O O   . LEU C 3 126 ? 150.301 142.547 200.613 1.00 62.41  ? 149 LEU C O   1 
ATOM   6939  C CB  . LEU C 3 126 ? 147.698 144.503 201.314 1.00 62.41  ? 149 LEU C CB  1 
ATOM   6940  C CG  . LEU C 3 126 ? 146.243 144.619 201.771 1.00 62.41  ? 149 LEU C CG  1 
ATOM   6941  C CD1 . LEU C 3 126 ? 146.059 145.826 202.678 1.00 62.41  ? 149 LEU C CD1 1 
ATOM   6942  C CD2 . LEU C 3 126 ? 145.308 144.697 200.575 1.00 62.41  ? 149 LEU C CD2 1 
ATOM   6943  N N   . ILE C 3 127 ? 149.901 144.216 199.151 1.00 47.31  ? 150 ILE C N   1 
ATOM   6944  C CA  . ILE C 3 127 ? 151.290 144.346 198.725 1.00 47.31  ? 150 ILE C CA  1 
ATOM   6945  C C   . ILE C 3 127 ? 151.571 145.814 198.434 1.00 47.31  ? 150 ILE C C   1 
ATOM   6946  O O   . ILE C 3 127 ? 150.740 146.516 197.849 1.00 47.31  ? 150 ILE C O   1 
ATOM   6947  C CB  . ILE C 3 127 ? 151.590 143.447 197.504 1.00 47.31  ? 150 ILE C CB  1 
ATOM   6948  C CG1 . ILE C 3 127 ? 153.071 143.522 197.125 1.00 47.31  ? 150 ILE C CG1 1 
ATOM   6949  C CG2 . ILE C 3 127 ? 150.693 143.803 196.328 1.00 47.31  ? 150 ILE C CG2 1 
ATOM   6950  C CD1 . ILE C 3 127 ? 153.509 142.440 196.163 1.00 47.31  ? 150 ILE C CD1 1 
ATOM   6951  N N   . PHE C 3 128 ? 152.742 146.282 198.866 1.00 49.23  ? 151 PHE C N   1 
ATOM   6952  C CA  . PHE C 3 128 ? 153.162 147.663 198.685 1.00 49.23  ? 151 PHE C CA  1 
ATOM   6953  C C   . PHE C 3 128 ? 154.641 147.693 198.322 1.00 49.23  ? 151 PHE C C   1 
ATOM   6954  O O   . PHE C 3 128 ? 155.421 146.880 198.840 1.00 49.23  ? 151 PHE C O   1 
ATOM   6955  C CB  . PHE C 3 128 ? 152.926 148.500 199.950 1.00 49.23  ? 151 PHE C CB  1 
ATOM   6956  C CG  . PHE C 3 128 ? 151.530 148.404 200.490 1.00 49.23  ? 151 PHE C CG  1 
ATOM   6957  C CD1 . PHE C 3 128 ? 150.527 149.224 200.002 1.00 49.23  ? 151 PHE C CD1 1 
ATOM   6958  C CD2 . PHE C 3 128 ? 151.221 147.498 201.489 1.00 49.23  ? 151 PHE C CD2 1 
ATOM   6959  C CE1 . PHE C 3 128 ? 149.242 149.139 200.499 1.00 49.23  ? 151 PHE C CE1 1 
ATOM   6960  C CE2 . PHE C 3 128 ? 149.938 147.408 201.990 1.00 49.23  ? 151 PHE C CE2 1 
ATOM   6961  C CZ  . PHE C 3 128 ? 148.947 148.230 201.494 1.00 49.23  ? 151 PHE C CZ  1 
ATOM   6962  N N   . PRO C 3 129 ? 155.060 148.613 197.440 1.00 42.56  ? 152 PRO C N   1 
ATOM   6963  C CA  . PRO C 3 129 ? 154.203 149.588 196.760 1.00 42.56  ? 152 PRO C CA  1 
ATOM   6964  C C   . PRO C 3 129 ? 153.587 149.037 195.478 1.00 42.56  ? 152 PRO C C   1 
ATOM   6965  O O   . PRO C 3 129 ? 153.928 147.933 195.056 1.00 42.56  ? 152 PRO C O   1 
ATOM   6966  C CB  . PRO C 3 129 ? 155.167 150.730 196.451 1.00 42.56  ? 152 PRO C CB  1 
ATOM   6967  C CG  . PRO C 3 129 ? 156.467 150.042 196.223 1.00 42.56  ? 152 PRO C CG  1 
ATOM   6968  C CD  . PRO C 3 129 ? 156.484 148.827 197.123 1.00 42.56  ? 152 PRO C CD  1 
ATOM   6969  N N   . LYS C 3 130 ? 152.690 149.806 194.869 1.00 46.92  ? 153 LYS C N   1 
ATOM   6970  C CA  . LYS C 3 130 ? 151.993 149.403 193.656 1.00 46.92  ? 153 LYS C CA  1 
ATOM   6971  C C   . LYS C 3 130 ? 152.388 150.324 192.511 1.00 46.92  ? 153 LYS C C   1 
ATOM   6972  O O   . LYS C 3 130 ? 152.263 151.548 192.624 1.00 46.92  ? 153 LYS C O   1 
ATOM   6973  C CB  . LYS C 3 130 ? 150.478 149.433 193.862 1.00 46.92  ? 153 LYS C CB  1 
ATOM   6974  C CG  . LYS C 3 130 ? 150.004 148.645 195.071 1.00 46.92  ? 153 LYS C CG  1 
ATOM   6975  C CD  . LYS C 3 130 ? 148.520 148.847 195.319 1.00 46.92  ? 153 LYS C CD  1 
ATOM   6976  C CE  . LYS C 3 130 ? 148.075 148.138 196.588 1.00 46.92  ? 153 LYS C CE  1 
ATOM   6977  N NZ  . LYS C 3 130 ? 146.637 148.379 196.887 1.00 46.92  ? 153 LYS C NZ  1 
ATOM   6978  N N   . ASP C 3 131 ? 152.864 149.730 191.415 1.00 41.74  ? 154 ASP C N   1 
ATOM   6979  C CA  . ASP C 3 131 ? 153.244 150.458 190.204 1.00 41.74  ? 154 ASP C CA  1 
ATOM   6980  C C   . ASP C 3 131 ? 154.323 151.501 190.505 1.00 41.74  ? 154 ASP C C   1 
ATOM   6981  O O   . ASP C 3 131 ? 154.132 152.707 190.336 1.00 41.74  ? 154 ASP C O   1 
ATOM   6982  C CB  . ASP C 3 131 ? 152.017 151.102 189.550 1.00 41.74  ? 154 ASP C CB  1 
ATOM   6983  C CG  . ASP C 3 131 ? 150.865 150.132 189.397 1.00 41.74  ? 154 ASP C CG  1 
ATOM   6984  O OD1 . ASP C 3 131 ? 151.124 148.925 189.209 1.00 41.74  ? 154 ASP C OD1 1 
ATOM   6985  O OD2 . ASP C 3 131 ? 149.700 150.575 189.466 1.00 41.74  ? 154 ASP C OD2 1 
ATOM   6986  N N   . LYS C 3 132 ? 155.472 151.008 190.956 1.00 34.02  ? 155 LYS C N   1 
ATOM   6987  C CA  . LYS C 3 132 ? 156.603 151.861 191.291 1.00 34.02  ? 155 LYS C CA  1 
ATOM   6988  C C   . LYS C 3 132 ? 157.425 152.148 190.042 1.00 34.02  ? 155 LYS C C   1 
ATOM   6989  O O   . LYS C 3 132 ? 157.726 151.236 189.265 1.00 34.02  ? 155 LYS C O   1 
ATOM   6990  C CB  . LYS C 3 132 ? 157.475 151.199 192.359 1.00 34.02  ? 155 LYS C CB  1 
ATOM   6991  C CG  . LYS C 3 132 ? 158.667 152.033 192.797 1.00 34.02  ? 155 LYS C CG  1 
ATOM   6992  C CD  . LYS C 3 132 ? 158.225 153.289 193.528 1.00 34.02  ? 155 LYS C CD  1 
ATOM   6993  C CE  . LYS C 3 132 ? 159.419 154.061 194.064 1.00 34.02  ? 155 LYS C CE  1 
ATOM   6994  N NZ  . LYS C 3 132 ? 159.001 155.270 194.826 1.00 34.02  ? 155 LYS C NZ  1 
ATOM   6995  N N   . VAL C 3 133 ? 157.782 153.415 189.851 1.00 38.53  ? 156 VAL C N   1 
ATOM   6996  C CA  . VAL C 3 133 ? 158.624 153.841 188.739 1.00 38.53  ? 156 VAL C CA  1 
ATOM   6997  C C   . VAL C 3 133 ? 160.038 154.037 189.268 1.00 38.53  ? 156 VAL C C   1 
ATOM   6998  O O   . VAL C 3 133 ? 160.258 154.820 190.200 1.00 38.53  ? 156 VAL C O   1 
ATOM   6999  C CB  . VAL C 3 133 ? 158.092 155.128 188.091 1.00 38.53  ? 156 VAL C CB  1 
ATOM   7000  C CG1 . VAL C 3 133 ? 158.978 155.539 186.927 1.00 38.53  ? 156 VAL C CG1 1 
ATOM   7001  C CG2 . VAL C 3 133 ? 156.658 154.933 187.631 1.00 38.53  ? 156 VAL C CG2 1 
ATOM   7002  N N   . LEU C 3 134 ? 160.996 153.330 188.676 1.00 48.95  ? 157 LEU C N   1 
ATOM   7003  C CA  . LEU C 3 134 ? 162.382 153.352 189.122 1.00 48.95  ? 157 LEU C CA  1 
ATOM   7004  C C   . LEU C 3 134 ? 163.296 153.605 187.930 1.00 48.95  ? 157 LEU C C   1 
ATOM   7005  O O   . LEU C 3 134 ? 162.851 153.705 186.782 1.00 48.95  ? 157 LEU C O   1 
ATOM   7006  C CB  . LEU C 3 134 ? 162.760 152.039 189.818 1.00 48.95  ? 157 LEU C CB  1 
ATOM   7007  C CG  . LEU C 3 134 ? 162.061 151.737 191.142 1.00 48.95  ? 157 LEU C CG  1 
ATOM   7008  C CD1 . LEU C 3 134 ? 162.395 150.329 191.599 1.00 48.95  ? 157 LEU C CD1 1 
ATOM   7009  C CD2 . LEU C 3 134 ? 162.454 152.756 192.199 1.00 48.95  ? 157 LEU C CD2 1 
ATOM   7010  N N   . GLU C 3 135 ? 164.590 153.708 188.214 1.00 59.31  ? 158 GLU C N   1 
ATOM   7011  C CA  . GLU C 3 135 ? 165.616 153.869 187.198 1.00 59.31  ? 158 GLU C CA  1 
ATOM   7012  C C   . GLU C 3 135 ? 166.408 152.576 187.062 1.00 59.31  ? 158 GLU C C   1 
ATOM   7013  O O   . GLU C 3 135 ? 166.630 151.859 188.043 1.00 59.31  ? 158 GLU C O   1 
ATOM   7014  C CB  . GLU C 3 135 ? 166.555 155.029 187.543 1.00 59.31  ? 158 GLU C CB  1 
ATOM   7015  C CG  . GLU C 3 135 ? 167.436 155.482 186.391 1.00 59.31  ? 158 GLU C CG  1 
ATOM   7016  C CD  . GLU C 3 135 ? 168.093 156.821 186.653 1.00 59.31  ? 158 GLU C CD  1 
ATOM   7017  O OE1 . GLU C 3 135 ? 167.672 157.516 187.601 1.00 59.31  ? 158 GLU C OE1 1 
ATOM   7018  O OE2 . GLU C 3 135 ? 169.030 157.181 185.910 1.00 59.31  ? 158 GLU C OE2 1 
ATOM   7019  N N   . GLU C 3 136 ? 166.825 152.280 185.834 1.00 57.72  ? 159 GLU C N   1 
ATOM   7020  C CA  . GLU C 3 136 ? 167.554 151.048 185.559 1.00 57.72  ? 159 GLU C CA  1 
ATOM   7021  C C   . GLU C 3 136 ? 168.866 151.020 186.331 1.00 57.72  ? 159 GLU C C   1 
ATOM   7022  O O   . GLU C 3 136 ? 169.763 151.831 186.082 1.00 57.72  ? 159 GLU C O   1 
ATOM   7023  C CB  . GLU C 3 136 ? 167.811 150.920 184.059 1.00 57.72  ? 159 GLU C CB  1 
ATOM   7024  C CG  . GLU C 3 136 ? 168.799 149.829 183.686 1.00 57.72  ? 159 GLU C CG  1 
ATOM   7025  C CD  . GLU C 3 136 ? 169.089 149.793 182.198 1.00 57.72  ? 159 GLU C CD  1 
ATOM   7026  O OE1 . GLU C 3 136 ? 168.156 150.036 181.404 1.00 57.72  ? 159 GLU C OE1 1 
ATOM   7027  O OE2 . GLU C 3 136 ? 170.248 149.522 181.823 1.00 57.72  ? 159 GLU C OE2 1 
ATOM   7028  N N   . GLY C 3 137 ? 168.975 150.083 187.273 1.00 53.54  ? 160 GLY C N   1 
ATOM   7029  C CA  . GLY C 3 137 ? 170.171 149.924 188.076 1.00 53.54  ? 160 GLY C CA  1 
ATOM   7030  C C   . GLY C 3 137 ? 170.017 150.285 189.537 1.00 53.54  ? 160 GLY C C   1 
ATOM   7031  O O   . GLY C 3 137 ? 171.017 150.270 190.265 1.00 53.54  ? 160 GLY C O   1 
ATOM   7032  N N   . SER C 3 138 ? 168.811 150.608 189.994 1.00 53.54  ? 161 SER C N   1 
ATOM   7033  C CA  . SER C 3 138 ? 168.574 150.987 191.376 1.00 53.54  ? 161 SER C CA  1 
ATOM   7034  C C   . SER C 3 138 ? 168.057 149.789 192.171 1.00 53.54  ? 161 SER C C   1 
ATOM   7035  O O   . SER C 3 138 ? 167.870 148.690 191.645 1.00 53.54  ? 161 SER C O   1 
ATOM   7036  C CB  . SER C 3 138 ? 167.594 152.160 191.447 1.00 53.54  ? 161 SER C CB  1 
ATOM   7037  O OG  . SER C 3 138 ? 167.664 152.807 192.705 1.00 53.54  ? 161 SER C OG  1 
ATOM   7038  N N   . ASN C 3 139 ? 167.826 150.012 193.460 1.00 61.05  ? 162 ASN C N   1 
ATOM   7039  C CA  . ASN C 3 139 ? 167.320 148.992 194.366 1.00 61.05  ? 162 ASN C CA  1 
ATOM   7040  C C   . ASN C 3 139 ? 165.899 149.330 194.798 1.00 61.05  ? 162 ASN C C   1 
ATOM   7041  O O   . ASN C 3 139 ? 165.411 150.447 194.607 1.00 61.05  ? 162 ASN C O   1 
ATOM   7042  C CB  . ASN C 3 139 ? 168.231 148.854 195.591 1.00 61.05  ? 162 ASN C CB  1 
ATOM   7043  C CG  . ASN C 3 139 ? 169.592 148.290 195.244 1.00 61.05  ? 162 ASN C CG  1 
ATOM   7044  O OD1 . ASN C 3 139 ? 169.737 147.528 194.289 1.00 61.05  ? 162 ASN C OD1 1 
ATOM   7045  N ND2 . ASN C 3 139 ? 170.600 148.665 196.021 1.00 61.05  ? 162 ASN C ND2 1 
ATOM   7046  N N   . VAL C 3 140 ? 165.236 148.341 195.397 1.00 50.88  ? 163 VAL C N   1 
ATOM   7047  C CA  . VAL C 3 140 ? 163.859 148.500 195.849 1.00 50.88  ? 163 VAL C CA  1 
ATOM   7048  C C   . VAL C 3 140 ? 163.586 147.440 196.905 1.00 50.88  ? 163 VAL C C   1 
ATOM   7049  O O   . VAL C 3 140 ? 164.196 146.368 196.901 1.00 50.88  ? 163 VAL C O   1 
ATOM   7050  C CB  . VAL C 3 140 ? 162.866 148.405 194.662 1.00 50.88  ? 163 VAL C CB  1 
ATOM   7051  C CG1 . VAL C 3 140 ? 162.799 146.984 194.126 1.00 50.88  ? 163 VAL C CG1 1 
ATOM   7052  C CG2 . VAL C 3 140 ? 161.486 148.903 195.067 1.00 50.88  ? 163 VAL C CG2 1 
ATOM   7053  N N   . THR C 3 141 ? 162.674 147.751 197.824 1.00 39.53  ? 164 THR C N   1 
ATOM   7054  C CA  . THR C 3 141 ? 162.252 146.824 198.870 1.00 39.53  ? 164 THR C CA  1 
ATOM   7055  C C   . THR C 3 141 ? 160.731 146.775 198.875 1.00 39.53  ? 164 THR C C   1 
ATOM   7056  O O   . THR C 3 141 ? 160.077 147.763 199.222 1.00 39.53  ? 164 THR C O   1 
ATOM   7057  C CB  . THR C 3 141 ? 162.786 147.247 200.238 1.00 39.53  ? 164 THR C CB  1 
ATOM   7058  O OG1 . THR C 3 141 ? 164.218 147.272 200.207 1.00 39.53  ? 164 THR C OG1 1 
ATOM   7059  C CG2 . THR C 3 141 ? 162.326 146.271 201.309 1.00 39.53  ? 164 THR C CG2 1 
ATOM   7060  N N   . ILE C 3 142 ? 160.171 145.630 198.494 1.00 40.80  ? 165 ILE C N   1 
ATOM   7061  C CA  . ILE C 3 142 ? 158.727 145.447 198.405 1.00 40.80  ? 165 ILE C CA  1 
ATOM   7062  C C   . ILE C 3 142 ? 158.258 144.662 199.621 1.00 40.80  ? 165 ILE C C   1 
ATOM   7063  O O   . ILE C 3 142 ? 158.776 143.575 199.907 1.00 40.80  ? 165 ILE C O   1 
ATOM   7064  C CB  . ILE C 3 142 ? 158.336 144.728 197.103 1.00 40.80  ? 165 ILE C CB  1 
ATOM   7065  C CG1 . ILE C 3 142 ? 158.670 145.599 195.891 1.00 40.80  ? 165 ILE C CG1 1 
ATOM   7066  C CG2 . ILE C 3 142 ? 156.858 144.371 197.114 1.00 40.80  ? 165 ILE C CG2 1 
ATOM   7067  C CD1 . ILE C 3 142 ? 158.279 144.981 194.568 1.00 40.80  ? 165 ILE C CD1 1 
ATOM   7068  N N   . CYS C 3 143 ? 157.279 145.209 200.334 1.00 44.92  ? 166 CYS C N   1 
ATOM   7069  C CA  . CYS C 3 143 ? 156.706 144.564 201.504 1.00 44.92  ? 166 CYS C CA  1 
ATOM   7070  C C   . CYS C 3 143 ? 155.376 143.912 201.148 1.00 44.92  ? 166 CYS C C   1 
ATOM   7071  O O   . CYS C 3 143 ? 154.649 144.380 200.269 1.00 44.92  ? 166 CYS C O   1 
ATOM   7072  C CB  . CYS C 3 143 ? 156.504 145.570 202.639 1.00 44.92  ? 166 CYS C CB  1 
ATOM   7073  S SG  . CYS C 3 143 ? 155.416 144.993 203.961 1.00 44.92  ? 166 CYS C SG  1 
ATOM   7074  N N   . LEU C 3 144 ? 155.066 142.821 201.843 1.00 52.66  ? 167 LEU C N   1 
ATOM   7075  C CA  . LEU C 3 144 ? 153.836 142.073 201.625 1.00 52.66  ? 167 LEU C CA  1 
ATOM   7076  C C   . LEU C 3 144 ? 153.213 141.741 202.970 1.00 52.66  ? 167 LEU C C   1 
ATOM   7077  O O   . LEU C 3 144 ? 153.897 141.242 203.869 1.00 52.66  ? 167 LEU C O   1 
ATOM   7078  C CB  . LEU C 3 144 ? 154.102 140.793 200.823 1.00 52.66  ? 167 LEU C CB  1 
ATOM   7079  C CG  . LEU C 3 144 ? 152.885 140.001 200.341 1.00 52.66  ? 167 LEU C CG  1 
ATOM   7080  C CD1 . LEU C 3 144 ? 153.159 139.397 198.977 1.00 52.66  ? 167 LEU C CD1 1 
ATOM   7081  C CD2 . LEU C 3 144 ? 152.515 138.908 201.333 1.00 52.66  ? 167 LEU C CD2 1 
ATOM   7082  N N   . MET C 3 145 ? 151.917 142.017 203.104 1.00 62.30  ? 168 MET C N   1 
ATOM   7083  C CA  . MET C 3 145 ? 151.181 141.774 204.339 1.00 62.30  ? 168 MET C CA  1 
ATOM   7084  C C   . MET C 3 145 ? 149.972 140.909 204.024 1.00 62.30  ? 168 MET C C   1 
ATOM   7085  O O   . MET C 3 145 ? 149.084 141.331 203.276 1.00 62.30  ? 168 MET C O   1 
ATOM   7086  C CB  . MET C 3 145 ? 150.748 143.091 204.989 1.00 62.30  ? 168 MET C CB  1 
ATOM   7087  C CG  . MET C 3 145 ? 149.840 142.921 206.194 1.00 62.30  ? 168 MET C CG  1 
ATOM   7088  S SD  . MET C 3 145 ? 149.488 144.489 207.011 1.00 62.30  ? 168 MET C SD  1 
ATOM   7089  C CE  . MET C 3 145 ? 148.905 145.463 205.626 1.00 62.30  ? 168 MET C CE  1 
ATOM   7090  N N   . TYR C 3 146 ? 149.938 139.709 204.591 1.00 72.05  ? 169 TYR C N   1 
ATOM   7091  C CA  . TYR C 3 146 ? 148.840 138.776 204.397 1.00 72.05  ? 169 TYR C CA  1 
ATOM   7092  C C   . TYR C 3 146 ? 148.018 138.659 205.674 1.00 72.05  ? 169 TYR C C   1 
ATOM   7093  O O   . TYR C 3 146 ? 148.407 139.135 206.743 1.00 72.05  ? 169 TYR C O   1 
ATOM   7094  C CB  . TYR C 3 146 ? 149.361 137.399 203.964 1.00 72.05  ? 169 TYR C CB  1 
ATOM   7095  C CG  . TYR C 3 146 ? 150.507 136.873 204.799 1.00 72.05  ? 169 TYR C CG  1 
ATOM   7096  C CD1 . TYR C 3 146 ? 151.820 136.996 204.367 1.00 72.05  ? 169 TYR C CD1 1 
ATOM   7097  C CD2 . TYR C 3 146 ? 150.275 136.248 206.017 1.00 72.05  ? 169 TYR C CD2 1 
ATOM   7098  C CE1 . TYR C 3 146 ? 152.870 136.514 205.125 1.00 72.05  ? 169 TYR C CE1 1 
ATOM   7099  C CE2 . TYR C 3 146 ? 151.318 135.764 206.782 1.00 72.05  ? 169 TYR C CE2 1 
ATOM   7100  C CZ  . TYR C 3 146 ? 152.613 135.899 206.332 1.00 72.05  ? 169 TYR C CZ  1 
ATOM   7101  O OH  . TYR C 3 146 ? 153.654 135.418 207.091 1.00 72.05  ? 169 TYR C OH  1 
ATOM   7102  N N   . GLY C 3 147 ? 146.864 138.010 205.548 1.00 86.36  ? 170 GLY C N   1 
ATOM   7103  C CA  . GLY C 3 147 ? 145.958 137.830 206.661 1.00 86.36  ? 170 GLY C CA  1 
ATOM   7104  C C   . GLY C 3 147 ? 146.437 136.775 207.637 1.00 86.36  ? 170 GLY C C   1 
ATOM   7105  O O   . GLY C 3 147 ? 147.605 136.378 207.652 1.00 86.36  ? 170 GLY C O   1 
ATOM   7106  N N   . GLN C 3 148 ? 145.505 136.316 208.471 1.00 91.07  ? 171 GLN C N   1 
ATOM   7107  C CA  . GLN C 3 148 ? 145.808 135.294 209.465 1.00 91.07  ? 171 GLN C CA  1 
ATOM   7108  C C   . GLN C 3 148 ? 145.642 133.883 208.914 1.00 91.07  ? 171 GLN C C   1 
ATOM   7109  O O   . GLN C 3 148 ? 146.420 132.988 209.261 1.00 91.07  ? 171 GLN C O   1 
ATOM   7110  C CB  . GLN C 3 148 ? 144.917 135.481 210.696 1.00 91.07  ? 171 GLN C CB  1 
ATOM   7111  C CG  . GLN C 3 148 ? 145.255 134.559 211.856 1.00 91.07  ? 171 GLN C CG  1 
ATOM   7112  C CD  . GLN C 3 148 ? 144.354 134.779 213.055 1.00 91.07  ? 171 GLN C CD  1 
ATOM   7113  O OE1 . GLN C 3 148 ? 144.559 134.189 214.116 1.00 91.07  ? 171 GLN C OE1 1 
ATOM   7114  N NE2 . GLN C 3 148 ? 143.349 135.630 212.891 1.00 91.07  ? 171 GLN C NE2 1 
ATOM   7115  N N   . ASN C 3 149 ? 144.643 133.667 208.057 1.00 93.24  ? 172 ASN C N   1 
ATOM   7116  C CA  . ASN C 3 149 ? 144.398 132.335 207.517 1.00 93.24  ? 172 ASN C CA  1 
ATOM   7117  C C   . ASN C 3 149 ? 145.383 131.968 206.416 1.00 93.24  ? 172 ASN C C   1 
ATOM   7118  O O   . ASN C 3 149 ? 145.650 130.780 206.202 1.00 93.24  ? 172 ASN C O   1 
ATOM   7119  C CB  . ASN C 3 149 ? 142.965 132.239 206.992 1.00 93.24  ? 172 ASN C CB  1 
ATOM   7120  C CG  . ASN C 3 149 ? 141.942 132.710 208.005 1.00 93.24  ? 172 ASN C CG  1 
ATOM   7121  O OD1 . ASN C 3 149 ? 142.150 132.596 209.213 1.00 93.24  ? 172 ASN C OD1 1 
ATOM   7122  N ND2 . ASN C 3 149 ? 140.829 133.245 207.518 1.00 93.24  ? 172 ASN C ND2 1 
ATOM   7123  N N   . VAL C 3 150 ? 145.928 132.960 205.709 1.00 83.63  ? 173 VAL C N   1 
ATOM   7124  C CA  . VAL C 3 150 ? 146.877 132.684 204.639 1.00 83.63  ? 173 VAL C CA  1 
ATOM   7125  C C   . VAL C 3 150 ? 148.175 132.154 205.232 1.00 83.63  ? 173 VAL C C   1 
ATOM   7126  O O   . VAL C 3 150 ? 148.653 132.639 206.267 1.00 83.63  ? 173 VAL C O   1 
ATOM   7127  C CB  . VAL C 3 150 ? 147.119 133.949 203.799 1.00 83.63  ? 173 VAL C CB  1 
ATOM   7128  C CG1 . VAL C 3 150 ? 147.939 133.619 202.561 1.00 83.63  ? 173 VAL C CG1 1 
ATOM   7129  C CG2 . VAL C 3 150 ? 145.794 134.585 203.411 1.00 83.63  ? 173 VAL C CG2 1 
ATOM   7130  N N   . TYR C 3 151 ? 148.753 131.149 204.578 1.00 94.79  ? 174 TYR C N   1 
ATOM   7131  C CA  . TYR C 3 151 ? 149.962 130.503 205.064 1.00 94.79  ? 174 TYR C CA  1 
ATOM   7132  C C   . TYR C 3 151 ? 150.829 130.089 203.883 1.00 94.79  ? 174 TYR C C   1 
ATOM   7133  O O   . TYR C 3 151 ? 150.322 129.735 202.815 1.00 94.79  ? 174 TYR C O   1 
ATOM   7134  C CB  . TYR C 3 151 ? 149.629 129.281 205.933 1.00 94.79  ? 174 TYR C CB  1 
ATOM   7135  C CG  . TYR C 3 151 ? 150.833 128.626 206.568 1.00 94.79  ? 174 TYR C CG  1 
ATOM   7136  C CD1 . TYR C 3 151 ? 151.518 129.244 207.606 1.00 94.79  ? 174 TYR C CD1 1 
ATOM   7137  C CD2 . TYR C 3 151 ? 151.283 127.386 206.134 1.00 94.79  ? 174 TYR C CD2 1 
ATOM   7138  C CE1 . TYR C 3 151 ? 152.619 128.646 208.192 1.00 94.79  ? 174 TYR C CE1 1 
ATOM   7139  C CE2 . TYR C 3 151 ? 152.382 126.781 206.713 1.00 94.79  ? 174 TYR C CE2 1 
ATOM   7140  C CZ  . TYR C 3 151 ? 153.047 127.415 207.741 1.00 94.79  ? 174 TYR C CZ  1 
ATOM   7141  O OH  . TYR C 3 151 ? 154.142 126.816 208.319 1.00 94.79  ? 174 TYR C OH  1 
ATOM   7142  N N   . ASN C 3 152 ? 152.146 130.141 204.092 1.00 90.35  ? 175 ASN C N   1 
ATOM   7143  C CA  . ASN C 3 152 ? 153.140 129.733 203.097 1.00 90.35  ? 175 ASN C CA  1 
ATOM   7144  C C   . ASN C 3 152 ? 152.989 130.532 201.800 1.00 90.35  ? 175 ASN C C   1 
ATOM   7145  O O   . ASN C 3 152 ? 152.684 129.996 200.734 1.00 90.35  ? 175 ASN C O   1 
ATOM   7146  C CB  . ASN C 3 152 ? 153.062 128.225 202.830 1.00 90.35  ? 175 ASN C CB  1 
ATOM   7147  C CG  . ASN C 3 152 ? 154.009 127.429 203.705 1.00 90.35  ? 175 ASN C CG  1 
ATOM   7148  O OD1 . ASN C 3 152 ? 154.956 127.974 204.273 1.00 90.35  ? 175 ASN C OD1 1 
ATOM   7149  N ND2 . ASN C 3 152 ? 153.761 126.129 203.816 1.00 90.35  ? 175 ASN C ND2 1 
ATOM   7150  N N   . VAL C 3 153 ? 153.211 131.837 201.914 1.00 70.52  ? 176 VAL C N   1 
ATOM   7151  C CA  . VAL C 3 153 ? 153.183 132.721 200.754 1.00 70.52  ? 176 VAL C CA  1 
ATOM   7152  C C   . VAL C 3 153 ? 154.523 132.636 200.038 1.00 70.52  ? 176 VAL C C   1 
ATOM   7153  O O   . VAL C 3 153 ? 155.584 132.690 200.671 1.00 70.52  ? 176 VAL C O   1 
ATOM   7154  C CB  . VAL C 3 153 ? 152.867 134.163 201.177 1.00 70.52  ? 176 VAL C CB  1 
ATOM   7155  C CG1 . VAL C 3 153 ? 152.644 135.037 199.956 1.00 70.52  ? 176 VAL C CG1 1 
ATOM   7156  C CG2 . VAL C 3 153 ? 151.652 134.191 202.089 1.00 70.52  ? 176 VAL C CG2 1 
ATOM   7157  N N   . SER C 3 154 ? 154.482 132.500 198.714 1.00 61.79  ? 177 SER C N   1 
ATOM   7158  C CA  . SER C 3 154 ? 155.686 132.366 197.899 1.00 61.79  ? 177 SER C CA  1 
ATOM   7159  C C   . SER C 3 154 ? 155.556 133.273 196.684 1.00 61.79  ? 177 SER C C   1 
ATOM   7160  O O   . SER C 3 154 ? 154.719 133.029 195.810 1.00 61.79  ? 177 SER C O   1 
ATOM   7161  C CB  . SER C 3 154 ? 155.904 130.913 197.474 1.00 61.79  ? 177 SER C CB  1 
ATOM   7162  O OG  . SER C 3 154 ? 154.810 130.437 196.709 1.00 61.79  ? 177 SER C OG  1 
ATOM   7163  N N   . CYS C 3 155 ? 156.382 134.312 196.628 1.00 55.87  ? 178 CYS C N   1 
ATOM   7164  C CA  . CYS C 3 155 ? 156.381 135.255 195.521 1.00 55.87  ? 178 CYS C CA  1 
ATOM   7165  C C   . CYS C 3 155 ? 157.451 134.878 194.505 1.00 55.87  ? 178 CYS C C   1 
ATOM   7166  O O   . CYS C 3 155 ? 158.467 134.266 194.843 1.00 55.87  ? 178 CYS C O   1 
ATOM   7167  C CB  . CYS C 3 155 ? 156.616 136.682 196.018 1.00 55.87  ? 178 CYS C CB  1 
ATOM   7168  S SG  . CYS C 3 155 ? 155.364 137.279 197.170 1.00 55.87  ? 178 CYS C SG  1 
ATOM   7169  N N   . LYS C 3 156 ? 157.210 135.252 193.251 1.00 51.82  ? 179 LYS C N   1 
ATOM   7170  C CA  . LYS C 3 156 ? 158.123 134.937 192.164 1.00 51.82  ? 179 LYS C CA  1 
ATOM   7171  C C   . LYS C 3 156 ? 158.175 136.098 191.182 1.00 51.82  ? 179 LYS C C   1 
ATOM   7172  O O   . LYS C 3 156 ? 157.225 136.874 191.058 1.00 51.82  ? 179 LYS C O   1 
ATOM   7173  C CB  . LYS C 3 156 ? 157.706 133.658 191.423 1.00 51.82  ? 179 LYS C CB  1 
ATOM   7174  C CG  . LYS C 3 156 ? 157.896 132.378 192.218 1.00 51.82  ? 179 LYS C CG  1 
ATOM   7175  C CD  . LYS C 3 156 ? 157.514 131.159 191.398 1.00 51.82  ? 179 LYS C CD  1 
ATOM   7176  C CE  . LYS C 3 156 ? 157.766 129.877 192.172 1.00 51.82  ? 179 LYS C CE  1 
ATOM   7177  N NZ  . LYS C 3 156 ? 157.428 128.674 191.366 1.00 51.82  ? 179 LYS C NZ  1 
ATOM   7178  N N   . LEU C 3 157 ? 159.303 136.202 190.482 1.00 47.70  ? 180 LEU C N   1 
ATOM   7179  C CA  . LEU C 3 157 ? 159.445 137.129 189.368 1.00 47.70  ? 180 LEU C CA  1 
ATOM   7180  C C   . LEU C 3 157 ? 158.810 136.478 188.141 1.00 47.70  ? 180 LEU C C   1 
ATOM   7181  O O   . LEU C 3 157 ? 158.024 135.536 188.289 1.00 47.70  ? 180 LEU C O   1 
ATOM   7182  C CB  . LEU C 3 157 ? 160.920 137.482 189.146 1.00 47.70  ? 180 LEU C CB  1 
ATOM   7183  C CG  . LEU C 3 157 ? 161.302 138.642 188.220 1.00 47.70  ? 180 LEU C CG  1 
ATOM   7184  C CD1 . LEU C 3 157 ? 160.773 139.957 188.767 1.00 47.70  ? 180 LEU C CD1 1 
ATOM   7185  C CD2 . LEU C 3 157 ? 162.805 138.704 188.008 1.00 47.70  ? 180 LEU C CD2 1 
ATOM   7186  N N   . GLN C 3 158 ? 159.100 136.992 186.942 1.00 48.10  ? 181 GLN C N   1 
ATOM   7187  C CA  . GLN C 3 158 ? 158.560 136.414 185.713 1.00 48.10  ? 181 GLN C CA  1 
ATOM   7188  C C   . GLN C 3 158 ? 158.701 134.895 185.704 1.00 48.10  ? 181 GLN C C   1 
ATOM   7189  O O   . GLN C 3 158 ? 157.704 134.165 185.690 1.00 48.10  ? 181 GLN C O   1 
ATOM   7190  C CB  . GLN C 3 158 ? 159.261 137.031 184.501 1.00 48.10  ? 181 GLN C CB  1 
ATOM   7191  C CG  . GLN C 3 158 ? 158.635 138.324 184.012 1.00 48.10  ? 181 GLN C CG  1 
ATOM   7192  C CD  . GLN C 3 158 ? 157.380 138.089 183.196 1.00 48.10  ? 181 GLN C CD  1 
ATOM   7193  O OE1 . GLN C 3 158 ? 156.298 137.881 183.745 1.00 48.10  ? 181 GLN C OE1 1 
ATOM   7194  N NE2 . GLN C 3 158 ? 157.519 138.118 181.876 1.00 48.10  ? 181 GLN C NE2 1 
ATOM   7195  N N   . ASP C 3 159 ? 159.940 134.396 185.716 1.00 63.59  ? 182 ASP C N   1 
ATOM   7196  C CA  . ASP C 3 159 ? 160.193 132.967 185.930 1.00 63.59  ? 182 ASP C CA  1 
ATOM   7197  C C   . ASP C 3 159 ? 161.487 132.798 186.730 1.00 63.59  ? 182 ASP C C   1 
ATOM   7198  O O   . ASP C 3 159 ? 162.568 132.619 186.161 1.00 63.59  ? 182 ASP C O   1 
ATOM   7199  C CB  . ASP C 3 159 ? 160.229 132.218 184.599 1.00 63.59  ? 182 ASP C CB  1 
ATOM   7200  C CG  . ASP C 3 159 ? 161.203 132.826 183.601 1.00 63.59  ? 182 ASP C CG  1 
ATOM   7201  O OD1 . ASP C 3 159 ? 161.795 133.884 183.900 1.00 63.59  ? 182 ASP C OD1 1 
ATOM   7202  O OD2 . ASP C 3 159 ? 161.373 132.242 182.510 1.00 63.59  ? 182 ASP C OD2 1 
ATOM   7203  N N   . GLU C 3 160 ? 161.357 132.820 188.061 1.00 61.87  ? 183 GLU C N   1 
ATOM   7204  C CA  . GLU C 3 160 ? 162.438 132.538 189.001 1.00 61.87  ? 183 GLU C CA  1 
ATOM   7205  C C   . GLU C 3 160 ? 161.898 132.600 190.425 1.00 61.87  ? 183 GLU C C   1 
ATOM   7206  O O   . GLU C 3 160 ? 160.900 133.285 190.680 1.00 61.87  ? 183 GLU C O   1 
ATOM   7207  C CB  . GLU C 3 160 ? 163.601 133.520 188.834 1.00 61.87  ? 183 GLU C CB  1 
ATOM   7208  C CG  . GLU C 3 160 ? 163.385 134.876 189.478 1.00 61.87  ? 183 GLU C CG  1 
ATOM   7209  C CD  . GLU C 3 160 ? 164.551 135.817 189.252 1.00 61.87  ? 183 GLU C CD  1 
ATOM   7210  O OE1 . GLU C 3 160 ? 165.347 135.568 188.322 1.00 61.87  ? 183 GLU C OE1 1 
ATOM   7211  O OE2 . GLU C 3 160 ? 164.675 136.806 190.005 1.00 61.87  ? 183 GLU C OE2 1 
ATOM   7212  N N   . PRO C 3 161 ? 162.514 131.902 191.373 1.00 56.28  ? 184 PRO C N   1 
ATOM   7213  C CA  . PRO C 3 161 ? 162.120 132.055 192.775 1.00 56.28  ? 184 PRO C CA  1 
ATOM   7214  C C   . PRO C 3 161 ? 162.687 133.335 193.374 1.00 56.28  ? 184 PRO C C   1 
ATOM   7215  O O   . PRO C 3 161 ? 163.632 133.936 192.859 1.00 56.28  ? 184 PRO C O   1 
ATOM   7216  C CB  . PRO C 3 161 ? 162.720 130.817 193.457 1.00 56.28  ? 184 PRO C CB  1 
ATOM   7217  C CG  . PRO C 3 161 ? 163.131 129.898 192.336 1.00 56.28  ? 184 PRO C CG  1 
ATOM   7218  C CD  . PRO C 3 161 ? 163.463 130.794 191.190 1.00 56.28  ? 184 PRO C CD  1 
ATOM   7219  N N   . ILE C 3 162 ? 162.080 133.750 194.484 1.00 53.36  ? 185 ILE C N   1 
ATOM   7220  C CA  . ILE C 3 162 ? 162.503 134.935 195.221 1.00 53.36  ? 185 ILE C CA  1 
ATOM   7221  C C   . ILE C 3 162 ? 162.606 134.565 196.692 1.00 53.36  ? 185 ILE C C   1 
ATOM   7222  O O   . ILE C 3 162 ? 161.626 134.103 197.290 1.00 53.36  ? 185 ILE C O   1 
ATOM   7223  C CB  . ILE C 3 162 ? 161.538 136.117 195.025 1.00 53.36  ? 185 ILE C CB  1 
ATOM   7224  C CG1 . ILE C 3 162 ? 161.598 136.620 193.581 1.00 53.36  ? 185 ILE C CG1 1 
ATOM   7225  C CG2 . ILE C 3 162 ? 161.869 137.240 195.994 1.00 53.36  ? 185 ILE C CG2 1 
ATOM   7226  C CD1 . ILE C 3 162 ? 160.701 137.809 193.310 1.00 53.36  ? 185 ILE C CD1 1 
ATOM   7227  N N   . HIS C 3 163 ? 163.787 134.766 197.275 1.00 62.13  ? 186 HIS C N   1 
ATOM   7228  C CA  . HIS C 3 163 ? 164.038 134.436 198.677 1.00 62.13  ? 186 HIS C CA  1 
ATOM   7229  C C   . HIS C 3 163 ? 163.617 135.625 199.531 1.00 62.13  ? 186 HIS C C   1 
ATOM   7230  O O   . HIS C 3 163 ? 164.365 136.586 199.712 1.00 62.13  ? 186 HIS C O   1 
ATOM   7231  C CB  . HIS C 3 163 ? 165.504 134.079 198.890 1.00 62.13  ? 186 HIS C CB  1 
ATOM   7232  C CG  . HIS C 3 163 ? 165.848 133.762 200.312 1.00 62.13  ? 186 HIS C CG  1 
ATOM   7233  N ND1 . HIS C 3 163 ? 165.290 132.703 200.994 1.00 62.13  ? 186 HIS C ND1 1 
ATOM   7234  C CD2 . HIS C 3 163 ? 166.694 134.366 201.180 1.00 62.13  ? 186 HIS C CD2 1 
ATOM   7235  C CE1 . HIS C 3 163 ? 165.777 132.668 202.222 1.00 62.13  ? 186 HIS C CE1 1 
ATOM   7236  N NE2 . HIS C 3 163 ? 166.631 133.665 202.360 1.00 62.13  ? 186 HIS C NE2 1 
ATOM   7237  N N   . GLY C 3 164 ? 162.401 135.557 200.064 1.00 53.65  ? 187 GLY C N   1 
ATOM   7238  C CA  . GLY C 3 164 ? 161.877 136.626 200.888 1.00 53.65  ? 187 GLY C CA  1 
ATOM   7239  C C   . GLY C 3 164 ? 162.242 136.468 202.354 1.00 53.65  ? 187 GLY C C   1 
ATOM   7240  O O   . GLY C 3 164 ? 162.421 135.362 202.857 1.00 53.65  ? 187 GLY C O   1 
ATOM   7241  N N   . GLU C 3 165 ? 162.348 137.603 203.038 1.00 65.21  ? 188 GLU C N   1 
ATOM   7242  C CA  . GLU C 3 165 ? 162.672 137.648 204.458 1.00 65.21  ? 188 GLU C CA  1 
ATOM   7243  C C   . GLU C 3 165 ? 161.426 138.025 205.247 1.00 65.21  ? 188 GLU C C   1 
ATOM   7244  O O   . GLU C 3 165 ? 160.704 138.954 204.868 1.00 65.21  ? 188 GLU C O   1 
ATOM   7245  C CB  . GLU C 3 165 ? 163.796 138.648 204.731 1.00 65.21  ? 188 GLU C CB  1 
ATOM   7246  C CG  . GLU C 3 165 ? 164.320 138.619 206.156 1.00 65.21  ? 188 GLU C CG  1 
ATOM   7247  C CD  . GLU C 3 165 ? 165.204 139.808 206.474 1.00 65.21  ? 188 GLU C CD  1 
ATOM   7248  O OE1 . GLU C 3 165 ? 164.705 140.775 207.086 1.00 65.21  ? 188 GLU C OE1 1 
ATOM   7249  O OE2 . GLU C 3 165 ? 166.399 139.776 206.111 1.00 65.21  ? 188 GLU C OE2 1 
ATOM   7250  N N   . GLN C 3 166 ? 161.180 137.308 206.340 1.00 68.82  ? 189 GLN C N   1 
ATOM   7251  C CA  . GLN C 3 166 ? 160.011 137.546 207.185 1.00 68.82  ? 189 GLN C CA  1 
ATOM   7252  C C   . GLN C 3 166 ? 160.385 138.572 208.247 1.00 68.82  ? 189 GLN C C   1 
ATOM   7253  O O   . GLN C 3 166 ? 161.065 138.253 209.226 1.00 68.82  ? 189 GLN C O   1 
ATOM   7254  C CB  . GLN C 3 166 ? 159.524 136.244 207.810 1.00 68.82  ? 189 GLN C CB  1 
ATOM   7255  C CG  . GLN C 3 166 ? 159.004 135.233 206.802 1.00 68.82  ? 189 GLN C CG  1 
ATOM   7256  C CD  . GLN C 3 166 ? 158.508 133.960 207.457 1.00 68.82  ? 189 GLN C CD  1 
ATOM   7257  O OE1 . GLN C 3 166 ? 158.673 133.762 208.660 1.00 68.82  ? 189 GLN C OE1 1 
ATOM   7258  N NE2 . GLN C 3 166 ? 157.893 133.089 206.666 1.00 68.82  ? 189 GLN C NE2 1 
ATOM   7259  N N   . LEU C 3 167 ? 159.937 139.814 208.053 1.00 67.85  ? 190 LEU C N   1 
ATOM   7260  C CA  . LEU C 3 167 ? 160.215 140.862 209.030 1.00 67.85  ? 190 LEU C CA  1 
ATOM   7261  C C   . LEU C 3 167 ? 159.472 140.611 210.335 1.00 67.85  ? 190 LEU C C   1 
ATOM   7262  O O   . LEU C 3 167 ? 160.014 140.846 211.421 1.00 67.85  ? 190 LEU C O   1 
ATOM   7263  C CB  . LEU C 3 167 ? 159.843 142.227 208.452 1.00 67.85  ? 190 LEU C CB  1 
ATOM   7264  C CG  . LEU C 3 167 ? 159.849 143.413 209.420 1.00 67.85  ? 190 LEU C CG  1 
ATOM   7265  C CD1 . LEU C 3 167 ? 161.253 143.676 209.941 1.00 67.85  ? 190 LEU C CD1 1 
ATOM   7266  C CD2 . LEU C 3 167 ? 159.278 144.653 208.752 1.00 67.85  ? 190 LEU C CD2 1 
ATOM   7267  N N   . ASP C 3 168 ? 158.235 140.131 210.250 1.00 77.18  ? 191 ASP C N   1 
ATOM   7268  C CA  . ASP C 3 168 ? 157.424 139.849 211.425 1.00 77.18  ? 191 ASP C CA  1 
ATOM   7269  C C   . ASP C 3 168 ? 156.672 138.546 211.179 1.00 77.18  ? 191 ASP C C   1 
ATOM   7270  O O   . ASP C 3 168 ? 156.977 137.796 210.247 1.00 77.18  ? 191 ASP C O   1 
ATOM   7271  C CB  . ASP C 3 168 ? 156.482 141.022 211.732 1.00 77.18  ? 191 ASP C CB  1 
ATOM   7272  C CG  . ASP C 3 168 ? 156.186 141.159 213.211 1.00 77.18  ? 191 ASP C CG  1 
ATOM   7273  O OD1 . ASP C 3 168 ? 156.767 140.392 214.008 1.00 77.18  ? 191 ASP C OD1 1 
ATOM   7274  O OD2 . ASP C 3 168 ? 155.372 142.032 213.577 1.00 77.18  ? 191 ASP C OD2 1 
ATOM   7275  N N   . SER C 3 169 ? 155.678 138.274 212.026 1.00 77.98  ? 192 SER C N   1 
ATOM   7276  C CA  . SER C 3 169 ? 154.950 137.015 211.925 1.00 77.98  ? 192 SER C CA  1 
ATOM   7277  C C   . SER C 3 169 ? 153.983 137.006 210.748 1.00 77.98  ? 192 SER C C   1 
ATOM   7278  O O   . SER C 3 169 ? 153.722 135.942 210.174 1.00 77.98  ? 192 SER C O   1 
ATOM   7279  C CB  . SER C 3 169 ? 154.200 136.738 213.228 1.00 77.98  ? 192 SER C CB  1 
ATOM   7280  O OG  . SER C 3 169 ? 152.956 137.416 213.252 1.00 77.98  ? 192 SER C OG  1 
ATOM   7281  N N   . HIS C 3 170 ? 153.443 138.166 210.371 1.00 77.19  ? 193 HIS C N   1 
ATOM   7282  C CA  . HIS C 3 170 ? 152.432 138.238 209.322 1.00 77.19  ? 193 HIS C CA  1 
ATOM   7283  C C   . HIS C 3 170 ? 152.851 139.101 208.138 1.00 77.19  ? 193 HIS C C   1 
ATOM   7284  O O   . HIS C 3 170 ? 152.013 139.395 207.277 1.00 77.19  ? 193 HIS C O   1 
ATOM   7285  C CB  . HIS C 3 170 ? 151.109 138.754 209.897 1.00 77.19  ? 193 HIS C CB  1 
ATOM   7286  C CG  . HIS C 3 170 ? 150.332 137.717 210.646 1.00 77.19  ? 193 HIS C CG  1 
ATOM   7287  N ND1 . HIS C 3 170 ? 149.592 136.741 210.014 1.00 77.19  ? 193 HIS C ND1 1 
ATOM   7288  C CD2 . HIS C 3 170 ? 150.179 137.504 211.975 1.00 77.19  ? 193 HIS C CD2 1 
ATOM   7289  C CE1 . HIS C 3 170 ? 149.017 135.971 210.921 1.00 77.19  ? 193 HIS C CE1 1 
ATOM   7290  N NE2 . HIS C 3 170 ? 149.357 136.413 212.119 1.00 77.19  ? 193 HIS C NE2 1 
ATOM   7291  N N   . VAL C 3 171 ? 154.116 139.516 208.064 1.00 60.85  ? 194 VAL C N   1 
ATOM   7292  C CA  . VAL C 3 171 ? 154.608 140.303 206.942 1.00 60.85  ? 194 VAL C CA  1 
ATOM   7293  C C   . VAL C 3 171 ? 155.851 139.630 206.376 1.00 60.85  ? 194 VAL C C   1 
ATOM   7294  O O   . VAL C 3 171 ? 156.486 138.794 207.022 1.00 60.85  ? 194 VAL C O   1 
ATOM   7295  C CB  . VAL C 3 171 ? 154.919 141.765 207.332 1.00 60.85  ? 194 VAL C CB  1 
ATOM   7296  C CG1 . VAL C 3 171 ? 153.719 142.406 208.010 1.00 60.85  ? 194 VAL C CG1 1 
ATOM   7297  C CG2 . VAL C 3 171 ? 156.144 141.829 208.225 1.00 60.85  ? 194 VAL C CG2 1 
ATOM   7298  N N   . SER C 3 172 ? 156.191 140.009 205.146 1.00 56.61  ? 195 SER C N   1 
ATOM   7299  C CA  . SER C 3 172 ? 157.359 139.468 204.468 1.00 56.61  ? 195 SER C CA  1 
ATOM   7300  C C   . SER C 3 172 ? 157.949 140.542 203.569 1.00 56.61  ? 195 SER C C   1 
ATOM   7301  O O   . SER C 3 172 ? 157.214 141.260 202.885 1.00 56.61  ? 195 SER C O   1 
ATOM   7302  C CB  . SER C 3 172 ? 157.005 138.223 203.646 1.00 56.61  ? 195 SER C CB  1 
ATOM   7303  O OG  . SER C 3 172 ? 156.547 137.174 204.481 1.00 56.61  ? 195 SER C OG  1 
ATOM   7304  N N   . LEU C 3 173 ? 159.274 140.647 203.573 1.00 47.57  ? 196 LEU C N   1 
ATOM   7305  C CA  . LEU C 3 173 ? 159.990 141.644 202.792 1.00 47.57  ? 196 LEU C CA  1 
ATOM   7306  C C   . LEU C 3 173 ? 160.654 140.991 201.588 1.00 47.57  ? 196 LEU C C   1 
ATOM   7307  O O   . LEU C 3 173 ? 161.233 139.906 201.697 1.00 47.57  ? 196 LEU C O   1 
ATOM   7308  C CB  . LEU C 3 173 ? 161.044 142.356 203.643 1.00 47.57  ? 196 LEU C CB  1 
ATOM   7309  C CG  . LEU C 3 173 ? 160.532 143.102 204.875 1.00 47.57  ? 196 LEU C CG  1 
ATOM   7310  C CD1 . LEU C 3 173 ? 161.675 143.815 205.580 1.00 47.57  ? 196 LEU C CD1 1 
ATOM   7311  C CD2 . LEU C 3 173 ? 159.438 144.084 204.491 1.00 47.57  ? 196 LEU C CD2 1 
ATOM   7312  N N   . LEU C 3 174 ? 160.567 141.659 200.441 1.00 42.73  ? 197 LEU C N   1 
ATOM   7313  C CA  . LEU C 3 174 ? 161.211 141.217 199.212 1.00 42.73  ? 197 LEU C CA  1 
ATOM   7314  C C   . LEU C 3 174 ? 162.240 142.256 198.796 1.00 42.73  ? 197 LEU C C   1 
ATOM   7315  O O   . LEU C 3 174 ? 161.917 143.442 198.678 1.00 42.73  ? 197 LEU C O   1 
ATOM   7316  C CB  . LEU C 3 174 ? 160.187 141.007 198.094 1.00 42.73  ? 197 LEU C CB  1 
ATOM   7317  C CG  . LEU C 3 174 ? 159.039 140.040 198.387 1.00 42.73  ? 197 LEU C CG  1 
ATOM   7318  C CD1 . LEU C 3 174 ? 158.150 139.883 197.165 1.00 42.73  ? 197 LEU C CD1 1 
ATOM   7319  C CD2 . LEU C 3 174 ? 159.575 138.693 198.839 1.00 42.73  ? 197 LEU C CD2 1 
ATOM   7320  N N   . LYS C 3 175 ? 163.474 141.812 198.575 1.00 38.35  ? 198 LYS C N   1 
ATOM   7321  C CA  . LYS C 3 175 ? 164.575 142.692 198.211 1.00 38.35  ? 198 LYS C CA  1 
ATOM   7322  C C   . LYS C 3 175 ? 165.045 142.367 196.801 1.00 38.35  ? 198 LYS C C   1 
ATOM   7323  O O   . LYS C 3 175 ? 165.307 141.203 196.481 1.00 38.35  ? 198 LYS C O   1 
ATOM   7324  C CB  . LYS C 3 175 ? 165.733 142.557 199.202 1.00 38.35  ? 198 LYS C CB  1 
ATOM   7325  C CG  . LYS C 3 175 ? 165.369 142.933 200.628 1.00 38.35  ? 198 LYS C CG  1 
ATOM   7326  C CD  . LYS C 3 175 ? 166.573 142.843 201.549 1.00 38.35  ? 198 LYS C CD  1 
ATOM   7327  C CE  . LYS C 3 175 ? 166.219 143.277 202.961 1.00 38.35  ? 198 LYS C CE  1 
ATOM   7328  N NZ  . LYS C 3 175 ? 167.395 143.216 203.871 1.00 38.35  ? 198 LYS C NZ  1 
ATOM   7329  N N   . LEU C 3 176 ? 165.149 143.397 195.964 1.00 48.06  ? 199 LEU C N   1 
ATOM   7330  C CA  . LEU C 3 176 ? 165.598 143.261 194.584 1.00 48.06  ? 199 LEU C CA  1 
ATOM   7331  C C   . LEU C 3 176 ? 166.807 144.161 194.378 1.00 48.06  ? 199 LEU C C   1 
ATOM   7332  O O   . LEU C 3 176 ? 166.756 145.354 194.695 1.00 48.06  ? 199 LEU C O   1 
ATOM   7333  C CB  . LEU C 3 176 ? 164.481 143.623 193.604 1.00 48.06  ? 199 LEU C CB  1 
ATOM   7334  C CG  . LEU C 3 176 ? 163.119 142.979 193.864 1.00 48.06  ? 199 LEU C CG  1 
ATOM   7335  C CD1 . LEU C 3 176 ? 162.098 143.450 192.841 1.00 48.06  ? 199 LEU C CD1 1 
ATOM   7336  C CD2 . LEU C 3 176 ? 163.231 141.464 193.853 1.00 48.06  ? 199 LEU C CD2 1 
ATOM   7337  N N   . ASN C 3 177 ? 167.887 143.592 193.854 1.00 55.13  ? 200 ASN C N   1 
ATOM   7338  C CA  . ASN C 3 177 ? 169.126 144.323 193.638 1.00 55.13  ? 200 ASN C CA  1 
ATOM   7339  C C   . ASN C 3 177 ? 169.417 144.464 192.149 1.00 55.13  ? 200 ASN C C   1 
ATOM   7340  O O   . ASN C 3 177 ? 169.226 143.527 191.370 1.00 55.13  ? 200 ASN C O   1 
ATOM   7341  C CB  . ASN C 3 177 ? 170.297 143.624 194.331 1.00 55.13  ? 200 ASN C CB  1 
ATOM   7342  C CG  . ASN C 3 177 ? 170.106 143.517 195.830 1.00 55.13  ? 200 ASN C CG  1 
ATOM   7343  O OD1 . ASN C 3 177 ? 170.467 144.422 196.581 1.00 55.13  ? 200 ASN C OD1 1 
ATOM   7344  N ND2 . ASN C 3 177 ? 169.533 142.405 196.275 1.00 55.13  ? 200 ASN C ND2 1 
ATOM   7345  N N   . ASN C 3 178 ? 169.893 145.651 191.774 1.00 59.94  ? 201 ASN C N   1 
ATOM   7346  C CA  . ASN C 3 178 ? 170.261 146.016 190.402 1.00 59.94  ? 201 ASN C CA  1 
ATOM   7347  C C   . ASN C 3 178 ? 169.257 145.473 189.384 1.00 59.94  ? 201 ASN C C   1 
ATOM   7348  O O   . ASN C 3 178 ? 169.576 144.663 188.514 1.00 59.94  ? 201 ASN C O   1 
ATOM   7349  C CB  . ASN C 3 178 ? 171.690 145.575 190.064 1.00 59.94  ? 201 ASN C CB  1 
ATOM   7350  C CG  . ASN C 3 178 ? 171.983 144.143 190.467 1.00 59.94  ? 201 ASN C CG  1 
ATOM   7351  O OD1 . ASN C 3 178 ? 171.588 143.199 189.783 1.00 59.94  ? 201 ASN C OD1 1 
ATOM   7352  N ND2 . ASN C 3 178 ? 172.679 143.976 191.585 1.00 59.94  ? 201 ASN C ND2 1 
ATOM   7353  N N   . VAL C 3 179 ? 168.013 145.940 189.522 1.00 55.27  ? 202 VAL C N   1 
ATOM   7354  C CA  . VAL C 3 179 ? 166.962 145.544 188.594 1.00 55.27  ? 202 VAL C CA  1 
ATOM   7355  C C   . VAL C 3 179 ? 167.321 145.994 187.185 1.00 55.27  ? 202 VAL C C   1 
ATOM   7356  O O   . VAL C 3 179 ? 167.877 147.080 186.977 1.00 55.27  ? 202 VAL C O   1 
ATOM   7357  C CB  . VAL C 3 179 ? 165.609 146.123 189.038 1.00 55.27  ? 202 VAL C CB  1 
ATOM   7358  C CG1 . VAL C 3 179 ? 165.109 145.405 190.280 1.00 55.27  ? 202 VAL C CG1 1 
ATOM   7359  C CG2 . VAL C 3 179 ? 165.729 147.616 189.299 1.00 55.27  ? 202 VAL C CG2 1 
ATOM   7360  N N   . VAL C 3 180 ? 167.008 145.151 186.207 1.00 47.50  ? 203 VAL C N   1 
ATOM   7361  C CA  . VAL C 3 180 ? 167.352 145.411 184.817 1.00 47.50  ? 203 VAL C CA  1 
ATOM   7362  C C   . VAL C 3 180 ? 166.085 145.734 184.037 1.00 47.50  ? 203 VAL C C   1 
ATOM   7363  O O   . VAL C 3 180 ? 164.966 145.407 184.442 1.00 47.50  ? 203 VAL C O   1 
ATOM   7364  C CB  . VAL C 3 180 ? 168.102 144.225 184.178 1.00 47.50  ? 203 VAL C CB  1 
ATOM   7365  C CG1 . VAL C 3 180 ? 169.332 143.872 184.999 1.00 47.50  ? 203 VAL C CG1 1 
ATOM   7366  C CG2 . VAL C 3 180 ? 167.180 143.024 184.044 1.00 47.50  ? 203 VAL C CG2 1 
ATOM   7367  N N   . PHE C 3 181 ? 166.276 146.392 182.896 1.00 45.95  ? 204 PHE C N   1 
ATOM   7368  C CA  . PHE C 3 181 ? 165.167 146.764 182.027 1.00 45.95  ? 204 PHE C CA  1 
ATOM   7369  C C   . PHE C 3 181 ? 164.737 145.555 181.206 1.00 45.95  ? 204 PHE C C   1 
ATOM   7370  O O   . PHE C 3 181 ? 165.557 144.945 180.511 1.00 45.95  ? 204 PHE C O   1 
ATOM   7371  C CB  . PHE C 3 181 ? 165.573 147.921 181.116 1.00 45.95  ? 204 PHE C CB  1 
ATOM   7372  C CG  . PHE C 3 181 ? 164.474 148.397 180.210 1.00 45.95  ? 204 PHE C CG  1 
ATOM   7373  C CD1 . PHE C 3 181 ? 164.401 147.961 178.898 1.00 45.95  ? 204 PHE C CD1 1 
ATOM   7374  C CD2 . PHE C 3 181 ? 163.517 149.285 180.669 1.00 45.95  ? 204 PHE C CD2 1 
ATOM   7375  C CE1 . PHE C 3 181 ? 163.393 148.399 178.062 1.00 45.95  ? 204 PHE C CE1 1 
ATOM   7376  C CE2 . PHE C 3 181 ? 162.506 149.727 179.837 1.00 45.95  ? 204 PHE C CE2 1 
ATOM   7377  C CZ  . PHE C 3 181 ? 162.444 149.283 178.533 1.00 45.95  ? 204 PHE C CZ  1 
ATOM   7378  N N   . LEU C 3 182 ? 163.454 145.209 181.286 1.00 44.92  ? 205 LEU C N   1 
ATOM   7379  C CA  . LEU C 3 182 ? 162.893 144.089 180.542 1.00 44.92  ? 205 LEU C CA  1 
ATOM   7380  C C   . LEU C 3 182 ? 162.045 144.540 179.363 1.00 44.92  ? 205 LEU C C   1 
ATOM   7381  O O   . LEU C 3 182 ? 162.269 144.096 178.233 1.00 44.92  ? 205 LEU C O   1 
ATOM   7382  C CB  . LEU C 3 182 ? 162.062 143.201 181.481 1.00 44.92  ? 205 LEU C CB  1 
ATOM   7383  C CG  . LEU C 3 182 ? 161.648 141.813 180.984 1.00 44.92  ? 205 LEU C CG  1 
ATOM   7384  C CD1 . LEU C 3 182 ? 161.614 140.832 182.144 1.00 44.92  ? 205 LEU C CD1 1 
ATOM   7385  C CD2 . LEU C 3 182 ? 160.294 141.851 180.292 1.00 44.92  ? 205 LEU C CD2 1 
ATOM   7386  N N   . SER C 3 183 ? 161.073 145.417 179.599 1.00 47.46  ? 206 SER C N   1 
ATOM   7387  C CA  . SER C 3 183 ? 160.222 145.928 178.534 1.00 47.46  ? 206 SER C CA  1 
ATOM   7388  C C   . SER C 3 183 ? 159.576 147.220 179.009 1.00 47.46  ? 206 SER C C   1 
ATOM   7389  O O   . SER C 3 183 ? 159.523 147.505 180.208 1.00 47.46  ? 206 SER C O   1 
ATOM   7390  C CB  . SER C 3 183 ? 159.154 144.907 178.125 1.00 47.46  ? 206 SER C CB  1 
ATOM   7391  O OG  . SER C 3 183 ? 158.609 145.222 176.856 1.00 47.46  ? 206 SER C OG  1 
ATOM   7392  N N   . ASP C 3 184 ? 159.082 148.000 178.047 1.00 52.27  ? 207 ASP C N   1 
ATOM   7393  C CA  . ASP C 3 184 ? 158.450 149.275 178.365 1.00 52.27  ? 207 ASP C CA  1 
ATOM   7394  C C   . ASP C 3 184 ? 157.096 149.114 179.041 1.00 52.27  ? 207 ASP C C   1 
ATOM   7395  O O   . ASP C 3 184 ? 156.514 150.118 179.465 1.00 52.27  ? 207 ASP C O   1 
ATOM   7396  C CB  . ASP C 3 184 ? 158.296 150.116 177.096 1.00 52.27  ? 207 ASP C CB  1 
ATOM   7397  C CG  . ASP C 3 184 ? 157.447 149.433 176.042 1.00 52.27  ? 207 ASP C CG  1 
ATOM   7398  O OD1 . ASP C 3 184 ? 156.204 149.498 176.143 1.00 52.27  ? 207 ASP C OD1 1 
ATOM   7399  O OD2 . ASP C 3 184 ? 158.024 148.832 175.112 1.00 52.27  ? 207 ASP C OD2 1 
ATOM   7400  N N   . THR C 3 185 ? 156.580 147.891 179.149 1.00 41.34  ? 208 THR C N   1 
ATOM   7401  C CA  . THR C 3 185 ? 155.291 147.640 179.777 1.00 41.34  ? 208 THR C CA  1 
ATOM   7402  C C   . THR C 3 185 ? 155.411 147.197 181.228 1.00 41.34  ? 208 THR C C   1 
ATOM   7403  O O   . THR C 3 185 ? 154.386 146.972 181.878 1.00 41.34  ? 208 THR C O   1 
ATOM   7404  C CB  . THR C 3 185 ? 154.510 146.590 178.982 1.00 41.34  ? 208 THR C CB  1 
ATOM   7405  O OG1 . THR C 3 185 ? 153.261 146.328 179.633 1.00 41.34  ? 208 THR C OG1 1 
ATOM   7406  C CG2 . THR C 3 185 ? 155.305 145.300 178.882 1.00 41.34  ? 208 THR C CG2 1 
ATOM   7407  N N   . GLY C 3 186 ? 156.624 147.065 181.749 1.00 38.40  ? 209 GLY C N   1 
ATOM   7408  C CA  . GLY C 3 186 ? 156.829 146.722 183.138 1.00 38.40  ? 209 GLY C CA  1 
ATOM   7409  C C   . GLY C 3 186 ? 157.063 145.234 183.342 1.00 38.40  ? 209 GLY C C   1 
ATOM   7410  O O   . GLY C 3 186 ? 156.766 144.398 182.486 1.00 38.40  ? 209 GLY C O   1 
ATOM   7411  N N   . THR C 3 187 ? 157.609 144.905 184.510 1.00 36.30  ? 210 THR C N   1 
ATOM   7412  C CA  . THR C 3 187 ? 157.895 143.528 184.892 1.00 36.30  ? 210 THR C CA  1 
ATOM   7413  C C   . THR C 3 187 ? 156.860 143.072 185.913 1.00 36.30  ? 210 THR C C   1 
ATOM   7414  O O   . THR C 3 187 ? 156.752 143.657 186.995 1.00 36.30  ? 210 THR C O   1 
ATOM   7415  C CB  . THR C 3 187 ? 159.305 143.402 185.467 1.00 36.30  ? 210 THR C CB  1 
ATOM   7416  O OG1 . THR C 3 187 ? 160.266 143.767 184.469 1.00 36.30  ? 210 THR C OG1 1 
ATOM   7417  C CG2 . THR C 3 187 ? 159.567 141.976 185.920 1.00 36.30  ? 210 THR C CG2 1 
ATOM   7418  N N   . ASN C 3 188 ? 156.110 142.028 185.570 1.00 36.25  ? 211 ASN C N   1 
ATOM   7419  C CA  . ASN C 3 188 ? 155.044 141.541 186.433 1.00 36.25  ? 211 ASN C CA  1 
ATOM   7420  C C   . ASN C 3 188 ? 155.619 140.712 187.574 1.00 36.25  ? 211 ASN C C   1 
ATOM   7421  O O   . ASN C 3 188 ? 156.444 139.820 187.351 1.00 36.25  ? 211 ASN C O   1 
ATOM   7422  C CB  . ASN C 3 188 ? 154.047 140.709 185.628 1.00 36.25  ? 211 ASN C CB  1 
ATOM   7423  C CG  . ASN C 3 188 ? 153.411 141.494 184.501 1.00 36.25  ? 211 ASN C CG  1 
ATOM   7424  O OD1 . ASN C 3 188 ? 153.089 142.671 184.654 1.00 36.25  ? 211 ASN C OD1 1 
ATOM   7425  N ND2 . ASN C 3 188 ? 153.229 140.845 183.357 1.00 36.25  ? 211 ASN C ND2 1 
ATOM   7426  N N   . ILE C 3 189 ? 155.182 141.009 188.796 1.00 34.31  ? 212 ILE C N   1 
ATOM   7427  C CA  . ILE C 3 189 ? 155.594 140.251 189.972 1.00 34.31  ? 212 ILE C CA  1 
ATOM   7428  C C   . ILE C 3 189 ? 154.390 139.500 190.520 1.00 34.31  ? 212 ILE C C   1 
ATOM   7429  O O   . ILE C 3 189 ? 153.608 140.047 191.305 1.00 34.31  ? 212 ILE C O   1 
ATOM   7430  C CB  . ILE C 3 189 ? 156.209 141.168 191.044 1.00 34.31  ? 212 ILE C CB  1 
ATOM   7431  C CG1 . ILE C 3 189 ? 157.373 141.967 190.458 1.00 34.31  ? 212 ILE C CG1 1 
ATOM   7432  C CG2 . ILE C 3 189 ? 156.670 140.353 192.244 1.00 34.31  ? 212 ILE C CG2 1 
ATOM   7433  C CD1 . ILE C 3 189 ? 158.057 142.870 191.459 1.00 34.31  ? 212 ILE C CD1 1 
ATOM   7434  N N   . ASN C 3 190 ? 154.229 138.245 190.110 1.00 46.25  ? 213 ASN C N   1 
ATOM   7435  C CA  . ASN C 3 190 ? 153.101 137.430 190.540 1.00 46.25  ? 213 ASN C CA  1 
ATOM   7436  C C   . ASN C 3 190 ? 153.474 136.649 191.793 1.00 46.25  ? 213 ASN C C   1 
ATOM   7437  O O   . ASN C 3 190 ? 154.549 136.045 191.861 1.00 46.25  ? 213 ASN C O   1 
ATOM   7438  C CB  . ASN C 3 190 ? 152.668 136.475 189.427 1.00 46.25  ? 213 ASN C CB  1 
ATOM   7439  C CG  . ASN C 3 190 ? 153.817 135.651 188.886 1.00 46.25  ? 213 ASN C CG  1 
ATOM   7440  O OD1 . ASN C 3 190 ? 154.118 134.574 189.399 1.00 46.25  ? 213 ASN C OD1 1 
ATOM   7441  N ND2 . ASN C 3 190 ? 154.463 136.152 187.841 1.00 46.25  ? 213 ASN C ND2 1 
ATOM   7442  N N   . CYS C 3 191 ? 152.583 136.666 192.782 1.00 55.20  ? 214 CYS C N   1 
ATOM   7443  C CA  . CYS C 3 191 ? 152.798 135.977 194.049 1.00 55.20  ? 214 CYS C CA  1 
ATOM   7444  C C   . CYS C 3 191 ? 151.560 135.158 194.375 1.00 55.20  ? 214 CYS C C   1 
ATOM   7445  O O   . CYS C 3 191 ? 150.494 135.721 194.645 1.00 55.20  ? 214 CYS C O   1 
ATOM   7446  C CB  . CYS C 3 191 ? 153.099 136.972 195.173 1.00 55.20  ? 214 CYS C CB  1 
ATOM   7447  S SG  . CYS C 3 191 ? 153.702 136.211 196.697 1.00 55.20  ? 214 CYS C SG  1 
ATOM   7448  N N   . GLN C 3 192 ? 151.701 133.836 194.355 1.00 66.15  ? 215 GLN C N   1 
ATOM   7449  C CA  . GLN C 3 192 ? 150.604 132.917 194.619 1.00 66.15  ? 215 GLN C CA  1 
ATOM   7450  C C   . GLN C 3 192 ? 150.822 132.219 195.954 1.00 66.15  ? 215 GLN C C   1 
ATOM   7451  O O   . GLN C 3 192 ? 151.940 131.803 196.273 1.00 66.15  ? 215 GLN C O   1 
ATOM   7452  C CB  . GLN C 3 192 ? 150.478 131.879 193.501 1.00 66.15  ? 215 GLN C CB  1 
ATOM   7453  C CG  . GLN C 3 192 ? 149.376 130.856 193.718 1.00 66.15  ? 215 GLN C CG  1 
ATOM   7454  C CD  . GLN C 3 192 ? 149.340 129.799 192.632 1.00 66.15  ? 215 GLN C CD  1 
ATOM   7455  O OE1 . GLN C 3 192 ? 150.209 129.757 191.761 1.00 66.15  ? 215 GLN C OE1 1 
ATOM   7456  N NE2 . GLN C 3 192 ? 148.333 128.935 192.680 1.00 66.15  ? 215 GLN C NE2 1 
ATOM   7457  N N   . ALA C 3 193 ? 149.749 132.092 196.730 1.00 85.68  ? 216 ALA C N   1 
ATOM   7458  C CA  . ALA C 3 193 ? 149.825 131.441 198.028 1.00 85.68  ? 216 ALA C CA  1 
ATOM   7459  C C   . ALA C 3 193 ? 149.734 129.929 197.874 1.00 85.68  ? 216 ALA C C   1 
ATOM   7460  O O   . ALA C 3 193 ? 148.932 129.416 197.088 1.00 85.68  ? 216 ALA C O   1 
ATOM   7461  C CB  . ALA C 3 193 ? 148.709 131.942 198.945 1.00 85.68  ? 216 ALA C CB  1 
ATOM   7462  N N   . THR C 3 194 ? 150.567 129.214 198.633 1.00 101.88 ? 217 THR C N   1 
ATOM   7463  C CA  . THR C 3 194 ? 150.550 127.755 198.578 1.00 101.88 ? 217 THR C CA  1 
ATOM   7464  C C   . THR C 3 194 ? 149.311 127.195 199.265 1.00 101.88 ? 217 THR C C   1 
ATOM   7465  O O   . THR C 3 194 ? 148.568 126.400 198.678 1.00 101.88 ? 217 THR C O   1 
ATOM   7466  C CB  . THR C 3 194 ? 151.820 127.189 199.213 1.00 101.88 ? 217 THR C CB  1 
ATOM   7467  O OG1 . THR C 3 194 ? 152.960 127.571 198.433 1.00 101.88 ? 217 THR C OG1 1 
ATOM   7468  C CG2 . THR C 3 194 ? 151.749 125.671 199.287 1.00 101.88 ? 217 THR C CG2 1 
ATOM   7469  N N   . LYS C 3 195 ? 149.072 127.599 200.508 1.00 112.35 ? 218 LYS C N   1 
ATOM   7470  C CA  . LYS C 3 195 ? 147.916 127.160 201.274 1.00 112.35 ? 218 LYS C CA  1 
ATOM   7471  C C   . LYS C 3 195 ? 146.900 128.290 201.379 1.00 112.35 ? 218 LYS C C   1 
ATOM   7472  O O   . LYS C 3 195 ? 147.185 129.451 201.074 1.00 112.35 ? 218 LYS C O   1 
ATOM   7473  C CB  . LYS C 3 195 ? 148.337 126.683 202.669 1.00 112.35 ? 218 LYS C CB  1 
ATOM   7474  C CG  . LYS C 3 195 ? 149.210 125.438 202.660 1.00 112.35 ? 218 LYS C CG  1 
ATOM   7475  C CD  . LYS C 3 195 ? 149.545 124.987 204.073 1.00 112.35 ? 218 LYS C CD  1 
ATOM   7476  C CE  . LYS C 3 195 ? 150.377 123.715 204.064 1.00 112.35 ? 218 LYS C CE  1 
ATOM   7477  N NZ  . LYS C 3 195 ? 149.652 122.581 203.427 1.00 112.35 ? 218 LYS C NZ  1 
ATOM   7478  N N   . GLY C 3 196 ? 145.696 127.932 201.818 1.00 125.80 ? 219 GLY C N   1 
ATOM   7479  C CA  . GLY C 3 196 ? 144.622 128.886 201.950 1.00 125.80 ? 219 GLY C CA  1 
ATOM   7480  C C   . GLY C 3 196 ? 143.940 129.161 200.626 1.00 125.80 ? 219 GLY C C   1 
ATOM   7481  O O   . GLY C 3 196 ? 143.810 128.277 199.773 1.00 125.80 ? 219 GLY C O   1 
ATOM   7482  N N   . PRO C 3 197 ? 143.482 130.398 200.431 1.00 125.22 ? 220 PRO C N   1 
ATOM   7483  C CA  . PRO C 3 197 ? 142.828 130.764 199.164 1.00 125.22 ? 220 PRO C CA  1 
ATOM   7484  C C   . PRO C 3 197 ? 143.813 130.692 198.006 1.00 125.22 ? 220 PRO C C   1 
ATOM   7485  O O   . PRO C 3 197 ? 144.843 131.369 198.007 1.00 125.22 ? 220 PRO C O   1 
ATOM   7486  C CB  . PRO C 3 197 ? 142.347 132.200 199.411 1.00 125.22 ? 220 PRO C CB  1 
ATOM   7487  C CG  . PRO C 3 197 ? 142.340 132.359 200.902 1.00 125.22 ? 220 PRO C CG  1 
ATOM   7488  C CD  . PRO C 3 197 ? 143.460 131.503 201.403 1.00 125.22 ? 220 PRO C CD  1 
ATOM   7489  N N   . LYS C 3 198 ? 143.489 129.864 197.015 1.00 118.12 ? 221 LYS C N   1 
ATOM   7490  C CA  . LYS C 3 198 ? 144.342 129.671 195.844 1.00 118.12 ? 221 LYS C CA  1 
ATOM   7491  C C   . LYS C 3 198 ? 143.991 130.735 194.811 1.00 118.12 ? 221 LYS C C   1 
ATOM   7492  O O   . LYS C 3 198 ? 142.977 130.634 194.116 1.00 118.12 ? 221 LYS C O   1 
ATOM   7493  C CB  . LYS C 3 198 ? 144.173 128.266 195.277 1.00 118.12 ? 221 LYS C CB  1 
ATOM   7494  C CG  . LYS C 3 198 ? 144.628 127.157 196.212 1.00 118.12 ? 221 LYS C CG  1 
ATOM   7495  C CD  . LYS C 3 198 ? 143.455 126.551 196.965 1.00 118.12 ? 221 LYS C CD  1 
ATOM   7496  C CE  . LYS C 3 198 ? 143.909 125.426 197.881 1.00 118.12 ? 221 LYS C CE  1 
ATOM   7497  N NZ  . LYS C 3 198 ? 142.773 124.836 198.640 1.00 118.12 ? 221 LYS C NZ  1 
ATOM   7498  N N   . ARG C 3 199 ? 144.834 131.758 194.709 1.00 92.82  ? 222 ARG C N   1 
ATOM   7499  C CA  . ARG C 3 199 ? 144.640 132.832 193.744 1.00 92.82  ? 222 ARG C CA  1 
ATOM   7500  C C   . ARG C 3 199 ? 145.995 133.472 193.469 1.00 92.82  ? 222 ARG C C   1 
ATOM   7501  O O   . ARG C 3 199 ? 147.013 133.092 194.054 1.00 92.82  ? 222 ARG C O   1 
ATOM   7502  C CB  . ARG C 3 199 ? 143.623 133.857 194.252 1.00 92.82  ? 222 ARG C CB  1 
ATOM   7503  C CG  . ARG C 3 199 ? 142.599 134.276 193.210 1.00 92.82  ? 222 ARG C CG  1 
ATOM   7504  C CD  . ARG C 3 199 ? 141.530 135.170 193.813 1.00 92.82  ? 222 ARG C CD  1 
ATOM   7505  N NE  . ARG C 3 199 ? 140.461 135.458 192.861 1.00 92.82  ? 222 ARG C NE  1 
ATOM   7506  C CZ  . ARG C 3 199 ? 139.410 136.226 193.128 1.00 92.82  ? 222 ARG C CZ  1 
ATOM   7507  N NH1 . ARG C 3 199 ? 139.282 136.787 194.322 1.00 92.82  ? 222 ARG C NH1 1 
ATOM   7508  N NH2 . ARG C 3 199 ? 138.485 136.433 192.200 1.00 92.82  ? 222 ARG C NH2 1 
ATOM   7509  N N   . ILE C 3 200 ? 146.001 134.452 192.571 1.00 55.25  ? 223 ILE C N   1 
ATOM   7510  C CA  . ILE C 3 200 ? 147.217 135.144 192.161 1.00 55.25  ? 223 ILE C CA  1 
ATOM   7511  C C   . ILE C 3 200 ? 147.036 136.632 192.418 1.00 55.25  ? 223 ILE C C   1 
ATOM   7512  O O   . ILE C 3 200 ? 146.038 137.225 191.992 1.00 55.25  ? 223 ILE C O   1 
ATOM   7513  C CB  . ILE C 3 200 ? 147.551 134.877 190.682 1.00 55.25  ? 223 ILE C CB  1 
ATOM   7514  C CG1 . ILE C 3 200 ? 148.068 133.448 190.505 1.00 55.25  ? 223 ILE C CG1 1 
ATOM   7515  C CG2 . ILE C 3 200 ? 148.573 135.882 190.172 1.00 55.25  ? 223 ILE C CG2 1 
ATOM   7516  C CD1 . ILE C 3 200 ? 148.624 133.165 189.128 1.00 55.25  ? 223 ILE C CD1 1 
ATOM   7517  N N   . PHE C 3 201 ? 148.000 137.231 193.116 1.00 50.16  ? 224 PHE C N   1 
ATOM   7518  C CA  . PHE C 3 201 ? 147.991 138.658 193.396 1.00 50.16  ? 224 PHE C CA  1 
ATOM   7519  C C   . PHE C 3 201 ? 149.407 139.199 193.266 1.00 50.16  ? 224 PHE C C   1 
ATOM   7520  O O   . PHE C 3 201 ? 150.382 138.510 193.576 1.00 50.16  ? 224 PHE C O   1 
ATOM   7521  C CB  . PHE C 3 201 ? 147.435 138.960 194.796 1.00 50.16  ? 224 PHE C CB  1 
ATOM   7522  C CG  . PHE C 3 201 ? 148.198 138.302 195.911 1.00 50.16  ? 224 PHE C CG  1 
ATOM   7523  C CD1 . PHE C 3 201 ? 147.892 137.013 196.311 1.00 50.16  ? 224 PHE C CD1 1 
ATOM   7524  C CD2 . PHE C 3 201 ? 149.216 138.976 196.565 1.00 50.16  ? 224 PHE C CD2 1 
ATOM   7525  C CE1 . PHE C 3 201 ? 148.591 136.406 197.338 1.00 50.16  ? 224 PHE C CE1 1 
ATOM   7526  C CE2 . PHE C 3 201 ? 149.918 138.375 197.591 1.00 50.16  ? 224 PHE C CE2 1 
ATOM   7527  C CZ  . PHE C 3 201 ? 149.605 137.088 197.978 1.00 50.16  ? 224 PHE C CZ  1 
ATOM   7528  N N   . GLY C 3 202 ? 149.509 140.437 192.804 1.00 50.13  ? 225 GLY C N   1 
ATOM   7529  C CA  . GLY C 3 202 ? 150.804 141.062 192.632 1.00 50.13  ? 225 GLY C CA  1 
ATOM   7530  C C   . GLY C 3 202 ? 150.663 142.421 191.984 1.00 50.13  ? 225 GLY C C   1 
ATOM   7531  O O   . GLY C 3 202 ? 149.559 142.885 191.685 1.00 50.13  ? 225 GLY C O   1 
ATOM   7532  N N   . THR C 3 203 ? 151.814 143.054 191.774 1.00 38.31  ? 226 THR C N   1 
ATOM   7533  C CA  . THR C 3 203 ? 151.886 144.375 191.169 1.00 38.31  ? 226 THR C CA  1 
ATOM   7534  C C   . THR C 3 203 ? 152.919 144.371 190.052 1.00 38.31  ? 226 THR C C   1 
ATOM   7535  O O   . THR C 3 203 ? 153.719 143.442 189.913 1.00 38.31  ? 226 THR C O   1 
ATOM   7536  C CB  . THR C 3 203 ? 152.236 145.451 192.205 1.00 38.31  ? 226 THR C CB  1 
ATOM   7537  O OG1 . THR C 3 203 ? 153.409 145.057 192.928 1.00 38.31  ? 226 THR C OG1 1 
ATOM   7538  C CG2 . THR C 3 203 ? 151.087 145.650 193.178 1.00 38.31  ? 226 THR C CG2 1 
ATOM   7539  N N   . VAL C 3 204 ? 152.893 145.430 189.249 1.00 34.86  ? 227 VAL C N   1 
ATOM   7540  C CA  . VAL C 3 204 ? 153.818 145.608 188.137 1.00 34.86  ? 227 VAL C CA  1 
ATOM   7541  C C   . VAL C 3 204 ? 154.906 146.582 188.558 1.00 34.86  ? 227 VAL C C   1 
ATOM   7542  O O   . VAL C 3 204 ? 154.623 147.629 189.152 1.00 34.86  ? 227 VAL C O   1 
ATOM   7543  C CB  . VAL C 3 204 ? 153.084 146.109 186.879 1.00 34.86  ? 227 VAL C CB  1 
ATOM   7544  C CG1 . VAL C 3 204 ? 154.041 146.193 185.702 1.00 34.86  ? 227 VAL C CG1 1 
ATOM   7545  C CG2 . VAL C 3 204 ? 151.911 145.201 186.555 1.00 34.86  ? 227 VAL C CG2 1 
ATOM   7546  N N   . LEU C 3 205 ? 156.155 146.239 188.253 1.00 34.90  ? 228 LEU C N   1 
ATOM   7547  C CA  . LEU C 3 205 ? 157.308 147.074 188.571 1.00 34.90  ? 228 LEU C CA  1 
ATOM   7548  C C   . LEU C 3 205 ? 157.785 147.740 187.286 1.00 34.90  ? 228 LEU C C   1 
ATOM   7549  O O   . LEU C 3 205 ? 158.332 147.073 186.401 1.00 34.90  ? 228 LEU C O   1 
ATOM   7550  C CB  . LEU C 3 205 ? 158.421 146.247 189.209 1.00 34.90  ? 228 LEU C CB  1 
ATOM   7551  C CG  . LEU C 3 205 ? 159.698 147.008 189.569 1.00 34.90  ? 228 LEU C CG  1 
ATOM   7552  C CD1 . LEU C 3 205 ? 159.407 148.086 190.600 1.00 34.90  ? 228 LEU C CD1 1 
ATOM   7553  C CD2 . LEU C 3 205 ? 160.769 146.053 190.073 1.00 34.90  ? 228 LEU C CD2 1 
ATOM   7554  N N   . PHE C 3 206 ? 157.577 149.050 187.185 1.00 33.28  ? 229 PHE C N   1 
ATOM   7555  C CA  . PHE C 3 206 ? 157.970 149.810 186.006 1.00 33.28  ? 229 PHE C CA  1 
ATOM   7556  C C   . PHE C 3 206 ? 159.431 150.225 186.133 1.00 33.28  ? 229 PHE C C   1 
ATOM   7557  O O   . PHE C 3 206 ? 159.806 150.912 187.089 1.00 33.28  ? 229 PHE C O   1 
ATOM   7558  C CB  . PHE C 3 206 ? 157.077 151.038 185.831 1.00 33.28  ? 229 PHE C CB  1 
ATOM   7559  C CG  . PHE C 3 206 ? 155.708 150.722 185.303 1.00 33.28  ? 229 PHE C CG  1 
ATOM   7560  C CD1 . PHE C 3 206 ? 155.497 150.556 183.945 1.00 33.28  ? 229 PHE C CD1 1 
ATOM   7561  C CD2 . PHE C 3 206 ? 154.631 150.598 186.162 1.00 33.28  ? 229 PHE C CD2 1 
ATOM   7562  C CE1 . PHE C 3 206 ? 154.239 150.267 183.456 1.00 33.28  ? 229 PHE C CE1 1 
ATOM   7563  C CE2 . PHE C 3 206 ? 153.370 150.310 185.678 1.00 33.28  ? 229 PHE C CE2 1 
ATOM   7564  C CZ  . PHE C 3 206 ? 153.174 150.144 184.323 1.00 33.28  ? 229 PHE C CZ  1 
ATOM   7565  N N   . VAL C 3 207 ? 160.250 149.806 185.172 1.00 42.80  ? 230 VAL C N   1 
ATOM   7566  C CA  . VAL C 3 207 ? 161.666 150.151 185.123 1.00 42.80  ? 230 VAL C CA  1 
ATOM   7567  C C   . VAL C 3 207 ? 161.907 150.990 183.877 1.00 42.80  ? 230 VAL C C   1 
ATOM   7568  O O   . VAL C 3 207 ? 161.505 150.603 182.774 1.00 42.80  ? 230 VAL C O   1 
ATOM   7569  C CB  . VAL C 3 207 ? 162.553 148.895 185.122 1.00 42.80  ? 230 VAL C CB  1 
ATOM   7570  C CG1 . VAL C 3 207 ? 164.022 149.284 185.108 1.00 42.80  ? 230 VAL C CG1 1 
ATOM   7571  C CG2 . VAL C 3 207 ? 162.239 148.024 186.327 1.00 42.80  ? 230 VAL C CG2 1 
ATOM   7572  N N   . SER C 3 208 ? 162.559 152.136 184.053 1.00 48.38  ? 231 SER C N   1 
ATOM   7573  C CA  . SER C 3 208 ? 162.827 153.063 182.966 1.00 48.38  ? 231 SER C CA  1 
ATOM   7574  C C   . SER C 3 208 ? 164.325 153.175 182.719 1.00 48.38  ? 231 SER C C   1 
ATOM   7575  O O   . SER C 3 208 ? 165.142 152.849 183.585 1.00 48.38  ? 231 SER C O   1 
ATOM   7576  C CB  . SER C 3 208 ? 162.250 154.448 183.269 1.00 48.38  ? 231 SER C CB  1 
ATOM   7577  O OG  . SER C 3 208 ? 163.176 155.232 184.000 1.00 48.38  ? 231 SER C OG  1 
ATOM   7578  N N   . LYS C 3 209 ? 164.677 153.643 181.525 1.00 52.18  ? 232 LYS C N   1 
ATOM   7579  C CA  . LYS C 3 209 ? 166.071 153.811 181.152 1.00 52.18  ? 232 LYS C CA  1 
ATOM   7580  C C   . LYS C 3 209 ? 166.625 155.116 181.720 1.00 52.18  ? 232 LYS C C   1 
ATOM   7581  O O   . LYS C 3 209 ? 165.918 155.906 182.352 1.00 52.18  ? 232 LYS C O   1 
ATOM   7582  C CB  . LYS C 3 209 ? 166.226 153.783 179.633 1.00 52.18  ? 232 LYS C CB  1 
ATOM   7583  C CG  . LYS C 3 209 ? 165.808 152.472 178.992 1.00 52.18  ? 232 LYS C CG  1 
ATOM   7584  C CD  . LYS C 3 209 ? 166.008 152.509 177.488 1.00 52.18  ? 232 LYS C CD  1 
ATOM   7585  C CE  . LYS C 3 209 ? 165.617 151.189 176.845 1.00 52.18  ? 232 LYS C CE  1 
ATOM   7586  N NZ  . LYS C 3 209 ? 165.791 151.219 175.367 1.00 52.18  ? 232 LYS C NZ  1 
ATOM   7587  N N   . VAL C 3 210 ? 167.914 155.338 181.485 1.00 50.38  ? 233 VAL C N   1 
ATOM   7588  C CA  . VAL C 3 210 ? 168.604 156.527 181.969 1.00 50.38  ? 233 VAL C CA  1 
ATOM   7589  C C   . VAL C 3 210 ? 168.538 157.607 180.898 1.00 50.38  ? 233 VAL C C   1 
ATOM   7590  O O   . VAL C 3 210 ? 168.773 157.337 179.714 1.00 50.38  ? 233 VAL C O   1 
ATOM   7591  C CB  . VAL C 3 210 ? 170.060 156.204 182.340 1.00 50.38  ? 233 VAL C CB  1 
ATOM   7592  C CG1 . VAL C 3 210 ? 170.743 157.426 182.934 1.00 50.38  ? 233 VAL C CG1 1 
ATOM   7593  C CG2 . VAL C 3 210 ? 170.112 155.034 183.309 1.00 50.38  ? 233 VAL C CG2 1 
ATOM   7594  N N   . LEU C 3 211 ? 168.218 158.831 181.312 1.00 53.98  ? 234 LEU C N   1 
ATOM   7595  C CA  . LEU C 3 211 ? 168.138 159.952 180.386 1.00 53.98  ? 234 LEU C CA  1 
ATOM   7596  C C   . LEU C 3 211 ? 169.537 160.444 180.037 1.00 53.98  ? 234 LEU C C   1 
ATOM   7597  O O   . LEU C 3 211 ? 170.358 160.692 180.925 1.00 53.98  ? 234 LEU C O   1 
ATOM   7598  C CB  . LEU C 3 211 ? 167.313 161.086 180.994 1.00 53.98  ? 234 LEU C CB  1 
ATOM   7599  C CG  . LEU C 3 211 ? 167.241 162.381 180.185 1.00 53.98  ? 234 LEU C CG  1 
ATOM   7600  C CD1 . LEU C 3 211 ? 166.673 162.118 178.802 1.00 53.98  ? 234 LEU C CD1 1 
ATOM   7601  C CD2 . LEU C 3 211 ? 166.413 163.423 180.916 1.00 53.98  ? 234 LEU C CD2 1 
ATOM   7602  N N   . GLU C 3 212 ? 169.805 160.585 178.743 1.00 68.36  ? 235 GLU C N   1 
ATOM   7603  C CA  . GLU C 3 212 ? 171.106 161.011 178.253 1.00 68.36  ? 235 GLU C CA  1 
ATOM   7604  C C   . GLU C 3 212 ? 171.114 162.506 177.958 1.00 68.36  ? 235 GLU C C   1 
ATOM   7605  O O   . GLU C 3 212 ? 170.072 163.164 177.905 1.00 68.36  ? 235 GLU C O   1 
ATOM   7606  C CB  . GLU C 3 212 ? 171.494 160.230 176.995 1.00 68.36  ? 235 GLU C CB  1 
ATOM   7607  C CG  . GLU C 3 212 ? 172.084 158.859 177.275 1.00 68.36  ? 235 GLU C CG  1 
ATOM   7608  C CD  . GLU C 3 212 ? 172.578 158.173 176.017 1.00 68.36  ? 235 GLU C CD  1 
ATOM   7609  O OE1 . GLU C 3 212 ? 171.970 158.383 174.947 1.00 68.36  ? 235 GLU C OE1 1 
ATOM   7610  O OE2 . GLU C 3 212 ? 173.574 157.424 176.099 1.00 68.36  ? 235 GLU C OE2 1 
ATOM   7611  N N   . GLU C 3 213 ? 172.318 163.035 177.765 1.00 64.36  ? 236 GLU C N   1 
ATOM   7612  C CA  . GLU C 3 213 ? 172.515 164.446 177.464 1.00 64.36  ? 236 GLU C CA  1 
ATOM   7613  C C   . GLU C 3 213 ? 172.452 164.676 175.955 1.00 64.36  ? 236 GLU C C   1 
ATOM   7614  O O   . GLU C 3 213 ? 172.963 163.861 175.182 1.00 64.36  ? 236 GLU C O   1 
ATOM   7615  C CB  . GLU C 3 213 ? 173.861 164.920 178.008 1.00 64.36  ? 236 GLU C CB  1 
ATOM   7616  C CG  . GLU C 3 213 ? 174.012 166.427 178.106 1.00 64.36  ? 236 GLU C CG  1 
ATOM   7617  C CD  . GLU C 3 213 ? 175.316 166.837 178.757 1.00 64.36  ? 236 GLU C CD  1 
ATOM   7618  O OE1 . GLU C 3 213 ? 176.256 166.015 178.775 1.00 64.36  ? 236 GLU C OE1 1 
ATOM   7619  O OE2 . GLU C 3 213 ? 175.403 167.980 179.253 1.00 64.36  ? 236 GLU C OE2 1 
ATOM   7620  N N   . PRO C 3 214 ? 171.821 165.762 175.509 1.00 59.92  ? 237 PRO C N   1 
ATOM   7621  C CA  . PRO C 3 214 ? 171.804 166.066 174.071 1.00 59.92  ? 237 PRO C CA  1 
ATOM   7622  C C   . PRO C 3 214 ? 173.215 166.267 173.537 1.00 59.92  ? 237 PRO C C   1 
ATOM   7623  O O   . PRO C 3 214 ? 174.038 166.951 174.148 1.00 59.92  ? 237 PRO C O   1 
ATOM   7624  C CB  . PRO C 3 214 ? 170.977 167.354 173.991 1.00 59.92  ? 237 PRO C CB  1 
ATOM   7625  C CG  . PRO C 3 214 ? 170.143 167.348 175.227 1.00 59.92  ? 237 PRO C CG  1 
ATOM   7626  C CD  . PRO C 3 214 ? 170.982 166.694 176.282 1.00 59.92  ? 237 PRO C CD  1 
ATOM   7627  N N   . LYS C 3 215 ? 173.488 165.662 172.384 1.00 61.75  ? 238 LYS C N   1 
ATOM   7628  C CA  . LYS C 3 215 ? 174.817 165.664 171.790 1.00 61.75  ? 238 LYS C CA  1 
ATOM   7629  C C   . LYS C 3 215 ? 174.823 166.473 170.499 1.00 61.75  ? 238 LYS C C   1 
ATOM   7630  O O   . LYS C 3 215 ? 173.875 166.410 169.710 1.00 61.75  ? 238 LYS C O   1 
ATOM   7631  C CB  . LYS C 3 215 ? 175.293 164.236 171.513 1.00 61.75  ? 238 LYS C CB  1 
ATOM   7632  C CG  . LYS C 3 215 ? 175.478 163.396 172.766 1.00 61.75  ? 238 LYS C CG  1 
ATOM   7633  C CD  . LYS C 3 215 ? 176.083 162.041 172.442 1.00 61.75  ? 238 LYS C CD  1 
ATOM   7634  C CE  . LYS C 3 215 ? 176.326 161.232 173.705 1.00 61.75  ? 238 LYS C CE  1 
ATOM   7635  N NZ  . LYS C 3 215 ? 176.947 159.912 173.409 1.00 61.75  ? 238 LYS C NZ  1 
ATOM   7636  N N   . ASN C 3 216 ? 175.907 167.223 170.293 1.00 69.40  ? 239 ASN C N   1 
ATOM   7637  C CA  . ASN C 3 216 ? 176.092 168.085 169.125 1.00 69.40  ? 239 ASN C CA  1 
ATOM   7638  C C   . ASN C 3 216 ? 174.909 169.038 168.946 1.00 69.40  ? 239 ASN C C   1 
ATOM   7639  O O   . ASN C 3 216 ? 174.172 168.989 167.960 1.00 69.40  ? 239 ASN C O   1 
ATOM   7640  C CB  . ASN C 3 216 ? 176.338 167.261 167.856 1.00 69.40  ? 239 ASN C CB  1 
ATOM   7641  C CG  . ASN C 3 216 ? 177.372 167.904 166.944 1.00 69.40  ? 239 ASN C CG  1 
ATOM   7642  O OD1 . ASN C 3 216 ? 177.686 169.082 167.116 1.00 69.40  ? 239 ASN C OD1 1 
ATOM   7643  N ND2 . ASN C 3 216 ? 177.913 167.153 165.976 1.00 69.40  ? 239 ASN C ND2 1 
ATOM   7644  N N   . VAL C 3 217 ? 174.741 169.917 169.929 1.00 64.27  ? 240 VAL C N   1 
ATOM   7645  C CA  . VAL C 3 217 ? 173.702 170.938 169.893 1.00 64.27  ? 240 VAL C CA  1 
ATOM   7646  C C   . VAL C 3 217 ? 174.256 172.140 169.137 1.00 64.27  ? 240 VAL C C   1 
ATOM   7647  O O   . VAL C 3 217 ? 175.192 172.798 169.598 1.00 64.27  ? 240 VAL C O   1 
ATOM   7648  C CB  . VAL C 3 217 ? 173.248 171.330 171.304 1.00 64.27  ? 240 VAL C CB  1 
ATOM   7649  C CG1 . VAL C 3 217 ? 172.136 172.363 171.235 1.00 64.27  ? 240 VAL C CG1 1 
ATOM   7650  C CG2 . VAL C 3 217 ? 172.796 170.102 172.076 1.00 64.27  ? 240 VAL C CG2 1 
ATOM   7651  N N   . SER C 3 218 ? 173.678 172.427 167.973 1.00 67.75  ? 241 SER C N   1 
ATOM   7652  C CA  . SER C 3 218 ? 174.099 173.551 167.152 1.00 67.75  ? 241 SER C CA  1 
ATOM   7653  C C   . SER C 3 218 ? 172.880 174.157 166.475 1.00 67.75  ? 241 SER C C   1 
ATOM   7654  O O   . SER C 3 218 ? 171.894 173.467 166.205 1.00 67.75  ? 241 SER C O   1 
ATOM   7655  C CB  . SER C 3 218 ? 175.130 173.127 166.098 1.00 67.75  ? 241 SER C CB  1 
ATOM   7656  O OG  . SER C 3 218 ? 174.494 172.663 164.921 1.00 67.75  ? 241 SER C OG  1 
ATOM   7657  N N   . CYS C 3 219 ? 172.959 175.455 166.194 1.00 68.47  ? 242 CYS C N   1 
ATOM   7658  C CA  . CYS C 3 219 ? 171.854 176.187 165.597 1.00 68.47  ? 242 CYS C CA  1 
ATOM   7659  C C   . CYS C 3 219 ? 172.373 177.002 164.419 1.00 68.47  ? 242 CYS C C   1 
ATOM   7660  O O   . CYS C 3 219 ? 173.582 177.134 164.212 1.00 68.47  ? 242 CYS C O   1 
ATOM   7661  C CB  . CYS C 3 219 ? 171.174 177.089 166.633 1.00 68.47  ? 242 CYS C CB  1 
ATOM   7662  S SG  . CYS C 3 219 ? 169.602 177.784 166.110 1.00 68.47  ? 242 CYS C SG  1 
ATOM   7663  N N   . GLU C 3 220 ? 171.444 177.563 163.647 1.00 67.74  ? 243 GLU C N   1 
ATOM   7664  C CA  . GLU C 3 220 ? 171.797 178.258 162.417 1.00 67.74  ? 243 GLU C CA  1 
ATOM   7665  C C   . GLU C 3 220 ? 170.723 179.283 162.085 1.00 67.74  ? 243 GLU C C   1 
ATOM   7666  O O   . GLU C 3 220 ? 169.608 179.235 162.609 1.00 67.74  ? 243 GLU C O   1 
ATOM   7667  C CB  . GLU C 3 220 ? 171.968 177.271 161.256 1.00 67.74  ? 243 GLU C CB  1 
ATOM   7668  C CG  . GLU C 3 220 ? 172.955 177.707 160.191 1.00 67.74  ? 243 GLU C CG  1 
ATOM   7669  C CD  . GLU C 3 220 ? 173.126 176.662 159.107 1.00 67.74  ? 243 GLU C CD  1 
ATOM   7670  O OE1 . GLU C 3 220 ? 172.142 175.957 158.802 1.00 67.74  ? 243 GLU C OE1 1 
ATOM   7671  O OE2 . GLU C 3 220 ? 174.244 176.542 158.564 1.00 67.74  ? 243 GLU C OE2 1 
ATOM   7672  N N   . THR C 3 221 ? 171.074 180.216 161.200 1.00 69.17  ? 244 THR C N   1 
ATOM   7673  C CA  . THR C 3 221 ? 170.145 181.223 160.710 1.00 69.17  ? 244 THR C CA  1 
ATOM   7674  C C   . THR C 3 221 ? 170.139 181.214 159.188 1.00 69.17  ? 244 THR C C   1 
ATOM   7675  O O   . THR C 3 221 ? 171.136 180.867 158.548 1.00 69.17  ? 244 THR C O   1 
ATOM   7676  C CB  . THR C 3 221 ? 170.497 182.632 161.218 1.00 69.17  ? 244 THR C CB  1 
ATOM   7677  O OG1 . THR C 3 221 ? 169.555 183.577 160.695 1.00 69.17  ? 244 THR C OG1 1 
ATOM   7678  C CG2 . THR C 3 221 ? 171.896 183.029 160.784 1.00 69.17  ? 244 THR C CG2 1 
ATOM   7679  N N   . ARG C 3 222 ? 168.999 181.593 158.613 1.00 72.14  ? 245 ARG C N   1 
ATOM   7680  C CA  . ARG C 3 222 ? 168.822 181.600 157.167 1.00 72.14  ? 245 ARG C CA  1 
ATOM   7681  C C   . ARG C 3 222 ? 168.502 182.981 156.618 1.00 72.14  ? 245 ARG C C   1 
ATOM   7682  O O   . ARG C 3 222 ? 169.124 183.412 155.639 1.00 72.14  ? 245 ARG C O   1 
ATOM   7683  C CB  . ARG C 3 222 ? 167.715 180.611 156.770 1.00 72.14  ? 245 ARG C CB  1 
ATOM   7684  C CG  . ARG C 3 222 ? 167.459 180.533 155.275 1.00 72.14  ? 245 ARG C CG  1 
ATOM   7685  C CD  . ARG C 3 222 ? 168.698 180.077 154.528 1.00 72.14  ? 245 ARG C CD  1 
ATOM   7686  N NE  . ARG C 3 222 ? 169.146 178.759 154.965 1.00 72.14  ? 245 ARG C NE  1 
ATOM   7687  C CZ  . ARG C 3 222 ? 168.769 177.617 154.400 1.00 72.14  ? 245 ARG C CZ  1 
ATOM   7688  N NH1 . ARG C 3 222 ? 169.227 176.463 154.863 1.00 72.14  ? 245 ARG C NH1 1 
ATOM   7689  N NH2 . ARG C 3 222 ? 167.934 177.630 153.370 1.00 72.14  ? 245 ARG C NH2 1 
ATOM   7690  N N   . ASP C 3 223 ? 167.545 183.692 157.220 1.00 76.58  ? 246 ASP C N   1 
ATOM   7691  C CA  . ASP C 3 223 ? 167.119 184.991 156.712 1.00 76.58  ? 246 ASP C CA  1 
ATOM   7692  C C   . ASP C 3 223 ? 166.951 186.007 157.836 1.00 76.58  ? 246 ASP C C   1 
ATOM   7693  O O   . ASP C 3 223 ? 166.122 186.918 157.734 1.00 76.58  ? 246 ASP C O   1 
ATOM   7694  C CB  . ASP C 3 223 ? 165.814 184.870 155.924 1.00 76.58  ? 246 ASP C CB  1 
ATOM   7695  C CG  . ASP C 3 223 ? 164.667 184.361 156.774 1.00 76.58  ? 246 ASP C CG  1 
ATOM   7696  O OD1 . ASP C 3 223 ? 164.929 183.629 157.752 1.00 76.58  ? 246 ASP C OD1 1 
ATOM   7697  O OD2 . ASP C 3 223 ? 163.503 184.692 156.466 1.00 76.58  ? 246 ASP C OD2 1 
ATOM   7698  N N   . PHE C 3 224 ? 167.723 185.860 158.914 1.00 80.46  ? 247 PHE C N   1 
ATOM   7699  C CA  . PHE C 3 224 ? 167.698 186.763 160.064 1.00 80.46  ? 247 PHE C CA  1 
ATOM   7700  C C   . PHE C 3 224 ? 166.322 186.837 160.720 1.00 80.46  ? 247 PHE C C   1 
ATOM   7701  O O   . PHE C 3 224 ? 166.002 187.826 161.387 1.00 80.46  ? 247 PHE C O   1 
ATOM   7702  C CB  . PHE C 3 224 ? 168.173 188.169 159.676 1.00 80.46  ? 247 PHE C CB  1 
ATOM   7703  C CG  . PHE C 3 224 ? 169.655 188.270 159.460 1.00 80.46  ? 247 PHE C CG  1 
ATOM   7704  C CD1 . PHE C 3 224 ? 170.475 188.817 160.432 1.00 80.46  ? 247 PHE C CD1 1 
ATOM   7705  C CD2 . PHE C 3 224 ? 170.229 187.817 158.284 1.00 80.46  ? 247 PHE C CD2 1 
ATOM   7706  C CE1 . PHE C 3 224 ? 171.839 188.911 160.235 1.00 80.46  ? 247 PHE C CE1 1 
ATOM   7707  C CE2 . PHE C 3 224 ? 171.592 187.908 158.083 1.00 80.46  ? 247 PHE C CE2 1 
ATOM   7708  C CZ  . PHE C 3 224 ? 172.398 188.456 159.060 1.00 80.46  ? 247 PHE C CZ  1 
ATOM   7709  N N   . LYS C 3 225 ? 165.503 185.811 160.546 1.00 79.92  ? 248 LYS C N   1 
ATOM   7710  C CA  . LYS C 3 225 ? 164.167 185.777 161.132 1.00 79.92  ? 248 LYS C CA  1 
ATOM   7711  C C   . LYS C 3 225 ? 163.903 184.517 161.942 1.00 79.92  ? 248 LYS C C   1 
ATOM   7712  O O   . LYS C 3 225 ? 163.205 184.583 162.957 1.00 79.92  ? 248 LYS C O   1 
ATOM   7713  C CB  . LYS C 3 225 ? 163.105 185.915 160.028 1.00 79.92  ? 248 LYS C CB  1 
ATOM   7714  C CG  . LYS C 3 225 ? 163.199 187.206 159.232 1.00 79.92  ? 248 LYS C CG  1 
ATOM   7715  C CD  . LYS C 3 225 ? 162.188 187.232 158.098 1.00 79.92  ? 248 LYS C CD  1 
ATOM   7716  C CE  . LYS C 3 225 ? 162.320 188.500 157.270 1.00 79.92  ? 248 LYS C CE  1 
ATOM   7717  N NZ  . LYS C 3 225 ? 161.380 188.513 156.115 1.00 79.92  ? 248 LYS C NZ  1 
ATOM   7718  N N   . THR C 3 226 ? 164.438 183.374 161.521 1.00 70.94  ? 249 THR C N   1 
ATOM   7719  C CA  . THR C 3 226 ? 164.222 182.110 162.208 1.00 70.94  ? 249 THR C CA  1 
ATOM   7720  C C   . THR C 3 226 ? 165.561 181.453 162.511 1.00 70.94  ? 249 THR C C   1 
ATOM   7721  O O   . THR C 3 226 ? 166.533 181.613 161.768 1.00 70.94  ? 249 THR C O   1 
ATOM   7722  C CB  . THR C 3 226 ? 163.357 181.154 161.375 1.00 70.94  ? 249 THR C CB  1 
ATOM   7723  O OG1 . THR C 3 226 ? 163.946 180.982 160.080 1.00 70.94  ? 249 THR C OG1 1 
ATOM   7724  C CG2 . THR C 3 226 ? 161.946 181.706 161.221 1.00 70.94  ? 249 THR C CG2 1 
ATOM   7725  N N   . LEU C 3 227 ? 165.600 180.711 163.616 1.00 63.02  ? 250 LEU C N   1 
ATOM   7726  C CA  . LEU C 3 227 ? 166.783 179.966 164.037 1.00 63.02  ? 250 LEU C CA  1 
ATOM   7727  C C   . LEU C 3 227 ? 166.399 178.498 164.159 1.00 63.02  ? 250 LEU C C   1 
ATOM   7728  O O   . LEU C 3 227 ? 165.723 178.107 165.116 1.00 63.02  ? 250 LEU C O   1 
ATOM   7729  C CB  . LEU C 3 227 ? 167.332 180.499 165.359 1.00 63.02  ? 250 LEU C CB  1 
ATOM   7730  C CG  . LEU C 3 227 ? 167.640 181.995 165.419 1.00 63.02  ? 250 LEU C CG  1 
ATOM   7731  C CD1 . LEU C 3 227 ? 168.237 182.371 166.764 1.00 63.02  ? 250 LEU C CD1 1 
ATOM   7732  C CD2 . LEU C 3 227 ? 168.572 182.390 164.291 1.00 63.02  ? 250 LEU C CD2 1 
ATOM   7733  N N   . ASP C 3 228 ? 166.832 177.688 163.195 1.00 65.63  ? 251 ASP C N   1 
ATOM   7734  C CA  . ASP C 3 228 ? 166.505 176.263 163.174 1.00 65.63  ? 251 ASP C CA  1 
ATOM   7735  C C   . ASP C 3 228 ? 167.585 175.495 163.930 1.00 65.63  ? 251 ASP C C   1 
ATOM   7736  O O   . ASP C 3 228 ? 168.529 174.957 163.350 1.00 65.63  ? 251 ASP C O   1 
ATOM   7737  C CB  . ASP C 3 228 ? 166.331 175.773 161.739 1.00 65.63  ? 251 ASP C CB  1 
ATOM   7738  C CG  . ASP C 3 228 ? 167.529 176.088 160.854 1.00 65.63  ? 251 ASP C CG  1 
ATOM   7739  O OD1 . ASP C 3 228 ? 168.460 176.775 161.325 1.00 65.63  ? 251 ASP C OD1 1 
ATOM   7740  O OD2 . ASP C 3 228 ? 167.542 175.646 159.684 1.00 65.63  ? 251 ASP C OD2 1 
ATOM   7741  N N   . CYS C 3 229 ? 167.429 175.429 165.248 1.00 64.29  ? 252 CYS C N   1 
ATOM   7742  C CA  . CYS C 3 229 ? 168.374 174.731 166.105 1.00 64.29  ? 252 CYS C CA  1 
ATOM   7743  C C   . CYS C 3 229 ? 168.023 173.249 166.174 1.00 64.29  ? 252 CYS C C   1 
ATOM   7744  O O   . CYS C 3 229 ? 166.846 172.878 166.206 1.00 64.29  ? 252 CYS C O   1 
ATOM   7745  C CB  . CYS C 3 229 ? 168.372 175.342 167.506 1.00 64.29  ? 252 CYS C CB  1 
ATOM   7746  S SG  . CYS C 3 229 ? 168.300 177.158 167.542 1.00 64.29  ? 252 CYS C SG  1 
ATOM   7747  N N   . SER C 3 230 ? 169.053 172.405 166.202 1.00 59.06  ? 253 SER C N   1 
ATOM   7748  C CA  . SER C 3 230 ? 168.869 170.962 166.189 1.00 59.06  ? 253 SER C CA  1 
ATOM   7749  C C   . SER C 3 230 ? 169.826 170.312 167.178 1.00 59.06  ? 253 SER C C   1 
ATOM   7750  O O   . SER C 3 230 ? 170.843 170.892 167.565 1.00 59.06  ? 253 SER C O   1 
ATOM   7751  C CB  . SER C 3 230 ? 169.085 170.382 164.785 1.00 59.06  ? 253 SER C CB  1 
ATOM   7752  O OG  . SER C 3 230 ? 170.448 170.067 164.568 1.00 59.06  ? 253 SER C OG  1 
ATOM   7753  N N   . TRP C 3 231 ? 169.485 169.090 167.580 1.00 57.17  ? 254 TRP C N   1 
ATOM   7754  C CA  . TRP C 3 231 ? 170.277 168.330 168.538 1.00 57.17  ? 254 TRP C CA  1 
ATOM   7755  C C   . TRP C 3 231 ? 169.928 166.854 168.386 1.00 57.17  ? 254 TRP C C   1 
ATOM   7756  O O   . TRP C 3 231 ? 169.154 166.466 167.508 1.00 57.17  ? 254 TRP C O   1 
ATOM   7757  C CB  . TRP C 3 231 ? 170.032 168.817 169.969 1.00 57.17  ? 254 TRP C CB  1 
ATOM   7758  C CG  . TRP C 3 231 ? 168.607 168.689 170.407 1.00 57.17  ? 254 TRP C CG  1 
ATOM   7759  C CD1 . TRP C 3 231 ? 168.009 167.585 170.939 1.00 57.17  ? 254 TRP C CD1 1 
ATOM   7760  C CD2 . TRP C 3 231 ? 167.597 169.703 170.346 1.00 57.17  ? 254 TRP C CD2 1 
ATOM   7761  N NE1 . TRP C 3 231 ? 166.690 167.849 171.217 1.00 57.17  ? 254 TRP C NE1 1 
ATOM   7762  C CE2 . TRP C 3 231 ? 166.412 169.143 170.862 1.00 57.17  ? 254 TRP C CE2 1 
ATOM   7763  C CE3 . TRP C 3 231 ? 167.580 171.030 169.909 1.00 57.17  ? 254 TRP C CE3 1 
ATOM   7764  C CZ2 . TRP C 3 231 ? 165.223 169.863 170.951 1.00 57.17  ? 254 TRP C CZ2 1 
ATOM   7765  C CZ3 . TRP C 3 231 ? 166.398 171.744 169.998 1.00 57.17  ? 254 TRP C CZ3 1 
ATOM   7766  C CH2 . TRP C 3 231 ? 165.236 171.159 170.515 1.00 57.17  ? 254 TRP C CH2 1 
ATOM   7767  N N   . GLU C 3 232 ? 170.509 166.030 169.258 1.00 65.41  ? 255 GLU C N   1 
ATOM   7768  C CA  . GLU C 3 232 ? 170.229 164.604 169.284 1.00 65.41  ? 255 GLU C CA  1 
ATOM   7769  C C   . GLU C 3 232 ? 169.389 164.260 170.502 1.00 65.41  ? 255 GLU C C   1 
ATOM   7770  O O   . GLU C 3 232 ? 169.768 164.610 171.627 1.00 65.41  ? 255 GLU C O   1 
ATOM   7771  C CB  . GLU C 3 232 ? 171.528 163.792 169.304 1.00 65.41  ? 255 GLU C CB  1 
ATOM   7772  C CG  . GLU C 3 232 ? 172.340 163.885 168.026 1.00 65.41  ? 255 GLU C CG  1 
ATOM   7773  C CD  . GLU C 3 232 ? 173.205 162.661 167.799 1.00 65.41  ? 255 GLU C CD  1 
ATOM   7774  O OE1 . GLU C 3 232 ? 172.647 161.584 167.500 1.00 65.41  ? 255 GLU C OE1 1 
ATOM   7775  O OE2 . GLU C 3 232 ? 174.442 162.774 167.925 1.00 65.41  ? 255 GLU C OE2 1 
ATOM   7776  N N   . PRO C 3 233 ? 168.253 163.579 170.326 1.00 60.40  ? 256 PRO C N   1 
ATOM   7777  C CA  . PRO C 3 233 ? 167.409 163.270 171.489 1.00 60.40  ? 256 PRO C CA  1 
ATOM   7778  C C   . PRO C 3 233 ? 167.980 162.180 172.378 1.00 60.40  ? 256 PRO C C   1 
ATOM   7779  O O   . PRO C 3 233 ? 167.734 162.197 173.590 1.00 60.40  ? 256 PRO C O   1 
ATOM   7780  C CB  . PRO C 3 233 ? 166.082 162.841 170.851 1.00 60.40  ? 256 PRO C CB  1 
ATOM   7781  C CG  . PRO C 3 233 ? 166.478 162.288 169.524 1.00 60.40  ? 256 PRO C CG  1 
ATOM   7782  C CD  . PRO C 3 233 ? 167.667 163.090 169.066 1.00 60.40  ? 256 PRO C CD  1 
ATOM   7783  N N   . GLY C 3 234 ? 168.734 161.238 171.820 1.00 59.73  ? 257 GLY C N   1 
ATOM   7784  C CA  . GLY C 3 234 ? 169.282 160.153 172.608 1.00 59.73  ? 257 GLY C CA  1 
ATOM   7785  C C   . GLY C 3 234 ? 168.391 158.928 172.637 1.00 59.73  ? 257 GLY C C   1 
ATOM   7786  O O   . GLY C 3 234 ? 167.860 158.515 171.602 1.00 59.73  ? 257 GLY C O   1 
ATOM   7787  N N   . VAL C 3 235 ? 168.220 158.340 173.815 1.00 60.55  ? 258 VAL C N   1 
ATOM   7788  C CA  . VAL C 3 235 ? 167.411 157.138 173.980 1.00 60.55  ? 258 VAL C CA  1 
ATOM   7789  C C   . VAL C 3 235 ? 166.035 157.531 174.501 1.00 60.55  ? 258 VAL C C   1 
ATOM   7790  O O   . VAL C 3 235 ? 165.898 158.462 175.304 1.00 60.55  ? 258 VAL C O   1 
ATOM   7791  C CB  . VAL C 3 235 ? 168.112 156.136 174.920 1.00 60.55  ? 258 VAL C CB  1 
ATOM   7792  C CG1 . VAL C 3 235 ? 168.309 156.737 176.305 1.00 60.55  ? 258 VAL C CG1 1 
ATOM   7793  C CG2 . VAL C 3 235 ? 167.335 154.830 174.995 1.00 60.55  ? 258 VAL C CG2 1 
ATOM   7794  N N   . ASP C 3 236 ? 165.007 156.830 174.029 1.00 57.60  ? 259 ASP C N   1 
ATOM   7795  C CA  . ASP C 3 236 ? 163.638 157.108 174.441 1.00 57.60  ? 259 ASP C CA  1 
ATOM   7796  C C   . ASP C 3 236 ? 163.366 156.489 175.807 1.00 57.60  ? 259 ASP C C   1 
ATOM   7797  O O   . ASP C 3 236 ? 163.686 155.320 176.043 1.00 57.60  ? 259 ASP C O   1 
ATOM   7798  C CB  . ASP C 3 236 ? 162.652 156.569 173.406 1.00 57.60  ? 259 ASP C CB  1 
ATOM   7799  C CG  . ASP C 3 236 ? 161.257 157.135 173.579 1.00 57.60  ? 259 ASP C CG  1 
ATOM   7800  O OD1 . ASP C 3 236 ? 161.082 158.051 174.410 1.00 57.60  ? 259 ASP C OD1 1 
ATOM   7801  O OD2 . ASP C 3 236 ? 160.333 156.663 172.883 1.00 57.60  ? 259 ASP C OD2 1 
ATOM   7802  N N   . THR C 3 237 ? 162.773 157.274 176.703 1.00 49.38  ? 260 THR C N   1 
ATOM   7803  C CA  . THR C 3 237 ? 162.461 156.847 178.064 1.00 49.38  ? 260 THR C CA  1 
ATOM   7804  C C   . THR C 3 237 ? 160.989 157.087 178.371 1.00 49.38  ? 260 THR C C   1 
ATOM   7805  O O   . THR C 3 237 ? 160.622 157.627 179.417 1.00 49.38  ? 260 THR C O   1 
ATOM   7806  C CB  . THR C 3 237 ? 163.337 157.567 179.086 1.00 49.38  ? 260 THR C CB  1 
ATOM   7807  O OG1 . THR C 3 237 ? 163.134 158.982 178.979 1.00 49.38  ? 260 THR C OG1 1 
ATOM   7808  C CG2 . THR C 3 237 ? 164.806 157.252 178.850 1.00 49.38  ? 260 THR C CG2 1 
ATOM   7809  N N   . THR C 3 238 ? 160.119 156.684 177.450 1.00 45.83  ? 261 THR C N   1 
ATOM   7810  C CA  . THR C 3 238 ? 158.680 156.853 177.593 1.00 45.83  ? 261 THR C CA  1 
ATOM   7811  C C   . THR C 3 238 ? 158.023 155.492 177.781 1.00 45.83  ? 261 THR C C   1 
ATOM   7812  O O   . THR C 3 238 ? 158.252 154.573 176.988 1.00 45.83  ? 261 THR C O   1 
ATOM   7813  C CB  . THR C 3 238 ? 158.086 157.560 176.374 1.00 45.83  ? 261 THR C CB  1 
ATOM   7814  O OG1 . THR C 3 238 ? 158.734 158.825 176.191 1.00 45.83  ? 261 THR C OG1 1 
ATOM   7815  C CG2 . THR C 3 238 ? 156.595 157.785 176.563 1.00 45.83  ? 261 THR C CG2 1 
ATOM   7816  N N   . LEU C 3 239 ? 157.209 155.369 178.827 1.00 48.58  ? 262 LEU C N   1 
ATOM   7817  C CA  . LEU C 3 239 ? 156.506 154.131 179.118 1.00 48.58  ? 262 LEU C CA  1 
ATOM   7818  C C   . LEU C 3 239 ? 155.188 154.084 178.346 1.00 48.58  ? 262 LEU C C   1 
ATOM   7819  O O   . LEU C 3 239 ? 154.836 155.007 177.608 1.00 48.58  ? 262 LEU C O   1 
ATOM   7820  C CB  . LEU C 3 239 ? 156.280 153.989 180.622 1.00 48.58  ? 262 LEU C CB  1 
ATOM   7821  C CG  . LEU C 3 239 ? 157.543 154.035 181.484 1.00 48.58  ? 262 LEU C CG  1 
ATOM   7822  C CD1 . LEU C 3 239 ? 157.209 153.769 182.942 1.00 48.58  ? 262 LEU C CD1 1 
ATOM   7823  C CD2 . LEU C 3 239 ? 158.578 153.043 180.979 1.00 48.58  ? 262 LEU C CD2 1 
ATOM   7824  N N   . THR C 3 240 ? 154.444 152.992 178.517 1.00 51.39  ? 263 THR C N   1 
ATOM   7825  C CA  . THR C 3 240 ? 153.219 152.770 177.757 1.00 51.39  ? 263 THR C CA  1 
ATOM   7826  C C   . THR C 3 240 ? 151.954 153.118 178.529 1.00 51.39  ? 263 THR C C   1 
ATOM   7827  O O   . THR C 3 240 ? 150.995 153.619 177.934 1.00 51.39  ? 263 THR C O   1 
ATOM   7828  C CB  . THR C 3 240 ? 153.141 151.313 177.287 1.00 51.39  ? 263 THR C CB  1 
ATOM   7829  O OG1 . THR C 3 240 ? 151.872 151.076 176.667 1.00 51.39  ? 263 THR C OG1 1 
ATOM   7830  C CG2 . THR C 3 240 ? 153.320 150.358 178.454 1.00 51.39  ? 263 THR C CG2 1 
ATOM   7831  N N   . TRP C 3 241 ? 151.919 152.874 179.836 1.00 43.61  ? 264 TRP C N   1 
ATOM   7832  C CA  . TRP C 3 241 ? 150.735 153.170 180.630 1.00 43.61  ? 264 TRP C CA  1 
ATOM   7833  C C   . TRP C 3 241 ? 150.719 154.658 180.978 1.00 43.61  ? 264 TRP C C   1 
ATOM   7834  O O   . TRP C 3 241 ? 151.489 155.458 180.439 1.00 43.61  ? 264 TRP C O   1 
ATOM   7835  C CB  . TRP C 3 241 ? 150.691 152.283 181.871 1.00 43.61  ? 264 TRP C CB  1 
ATOM   7836  C CG  . TRP C 3 241 ? 150.430 150.837 181.566 1.00 43.61  ? 264 TRP C CG  1 
ATOM   7837  C CD1 . TRP C 3 241 ? 151.363 149.859 181.376 1.00 43.61  ? 264 TRP C CD1 1 
ATOM   7838  C CD2 . TRP C 3 241 ? 149.152 150.205 181.415 1.00 43.61  ? 264 TRP C CD2 1 
ATOM   7839  N NE1 . TRP C 3 241 ? 150.746 148.660 181.117 1.00 43.61  ? 264 TRP C NE1 1 
ATOM   7840  C CE2 . TRP C 3 241 ? 149.389 148.845 181.135 1.00 43.61  ? 264 TRP C CE2 1 
ATOM   7841  C CE3 . TRP C 3 241 ? 147.832 150.658 181.490 1.00 43.61  ? 264 TRP C CE3 1 
ATOM   7842  C CZ2 . TRP C 3 241 ? 148.355 147.934 180.930 1.00 43.61  ? 264 TRP C CZ2 1 
ATOM   7843  C CZ3 . TRP C 3 241 ? 146.807 149.751 181.285 1.00 43.61  ? 264 TRP C CZ3 1 
ATOM   7844  C CH2 . TRP C 3 241 ? 147.075 148.405 181.009 1.00 43.61  ? 264 TRP C CH2 1 
ATOM   7845  N N   . ARG C 3 242 ? 149.832 155.048 181.891 1.00 53.47  ? 265 ARG C N   1 
ATOM   7846  C CA  . ARG C 3 242 ? 149.681 156.441 182.291 1.00 53.47  ? 265 ARG C CA  1 
ATOM   7847  C C   . ARG C 3 242 ? 150.751 156.902 183.276 1.00 53.47  ? 265 ARG C C   1 
ATOM   7848  O O   . ARG C 3 242 ? 150.577 157.949 183.911 1.00 53.47  ? 265 ARG C O   1 
ATOM   7849  C CB  . ARG C 3 242 ? 148.291 156.663 182.891 1.00 53.47  ? 265 ARG C CB  1 
ATOM   7850  C CG  . ARG C 3 242 ? 147.183 156.793 181.861 1.00 53.47  ? 265 ARG C CG  1 
ATOM   7851  C CD  . ARG C 3 242 ? 146.790 158.245 181.654 1.00 53.47  ? 265 ARG C CD  1 
ATOM   7852  N NE  . ARG C 3 242 ? 145.862 158.405 180.539 1.00 53.47  ? 265 ARG C NE  1 
ATOM   7853  C CZ  . ARG C 3 242 ? 145.282 159.554 180.207 1.00 53.47  ? 265 ARG C CZ  1 
ATOM   7854  N NH1 . ARG C 3 242 ? 145.532 160.652 180.907 1.00 53.47  ? 265 ARG C NH1 1 
ATOM   7855  N NH2 . ARG C 3 242 ? 144.453 159.605 179.174 1.00 53.47  ? 265 ARG C NH2 1 
ATOM   7856  N N   . LYS C 3 243 ? 151.847 156.155 183.421 1.00 52.56  ? 266 LYS C N   1 
ATOM   7857  C CA  . LYS C 3 243 ? 152.875 156.517 184.392 1.00 52.56  ? 266 LYS C CA  1 
ATOM   7858  C C   . LYS C 3 243 ? 153.768 157.638 183.870 1.00 52.56  ? 266 LYS C C   1 
ATOM   7859  O O   . LYS C 3 243 ? 153.831 158.722 184.460 1.00 52.56  ? 266 LYS C O   1 
ATOM   7860  C CB  . LYS C 3 243 ? 153.709 155.286 184.753 1.00 52.56  ? 266 LYS C CB  1 
ATOM   7861  C CG  . LYS C 3 243 ? 152.904 154.171 185.397 1.00 52.56  ? 266 LYS C CG  1 
ATOM   7862  C CD  . LYS C 3 243 ? 152.059 154.699 186.544 1.00 52.56  ? 266 LYS C CD  1 
ATOM   7863  C CE  . LYS C 3 243 ? 151.057 153.660 187.016 1.00 52.56  ? 266 LYS C CE  1 
ATOM   7864  N NZ  . LYS C 3 243 ? 150.178 154.189 188.095 1.00 52.56  ? 266 LYS C NZ  1 
ATOM   7865  N N   . GLN C 3 244 ? 154.466 157.395 182.763 1.00 51.90  ? 267 GLN C N   1 
ATOM   7866  C CA  . GLN C 3 244 ? 155.375 158.373 182.178 1.00 51.90  ? 267 GLN C CA  1 
ATOM   7867  C C   . GLN C 3 244 ? 155.046 158.522 180.702 1.00 51.90  ? 267 GLN C C   1 
ATOM   7868  O O   . GLN C 3 244 ? 155.169 157.561 179.937 1.00 51.90  ? 267 GLN C O   1 
ATOM   7869  C CB  . GLN C 3 244 ? 156.835 157.953 182.367 1.00 51.90  ? 267 GLN C CB  1 
ATOM   7870  C CG  . GLN C 3 244 ? 157.843 158.986 181.899 1.00 51.90  ? 267 GLN C CG  1 
ATOM   7871  C CD  . GLN C 3 244 ? 159.253 158.664 182.349 1.00 51.90  ? 267 GLN C CD  1 
ATOM   7872  O OE1 . GLN C 3 244 ? 159.465 157.775 183.173 1.00 51.90  ? 267 GLN C OE1 1 
ATOM   7873  N NE2 . GLN C 3 244 ? 160.226 159.387 181.810 1.00 51.90  ? 267 GLN C NE2 1 
ATOM   7874  N N   . ARG C 3 245 ? 154.631 159.720 180.306 1.00 54.14  ? 268 ARG C N   1 
ATOM   7875  C CA  . ARG C 3 245 ? 154.219 159.990 178.934 1.00 54.14  ? 268 ARG C CA  1 
ATOM   7876  C C   . ARG C 3 245 ? 155.070 161.039 178.239 1.00 54.14  ? 268 ARG C C   1 
ATOM   7877  O O   . ARG C 3 245 ? 155.440 160.853 177.078 1.00 54.14  ? 268 ARG C O   1 
ATOM   7878  C CB  . ARG C 3 245 ? 152.751 160.438 178.903 1.00 54.14  ? 268 ARG C CB  1 
ATOM   7879  C CG  . ARG C 3 245 ? 151.775 159.437 179.493 1.00 54.14  ? 268 ARG C CG  1 
ATOM   7880  C CD  . ARG C 3 245 ? 150.437 160.096 179.786 1.00 54.14  ? 268 ARG C CD  1 
ATOM   7881  N NE  . ARG C 3 245 ? 149.917 160.812 178.625 1.00 54.14  ? 268 ARG C NE  1 
ATOM   7882  C CZ  . ARG C 3 245 ? 148.880 161.642 178.661 1.00 54.14  ? 268 ARG C CZ  1 
ATOM   7883  N NH1 . ARG C 3 245 ? 148.248 161.867 179.804 1.00 54.14  ? 268 ARG C NH1 1 
ATOM   7884  N NH2 . ARG C 3 245 ? 148.477 162.250 177.554 1.00 54.14  ? 268 ARG C NH2 1 
ATOM   7885  N N   . PHE C 3 246 ? 155.391 162.138 178.915 1.00 49.75  ? 269 PHE C N   1 
ATOM   7886  C CA  . PHE C 3 246 ? 156.034 163.281 178.284 1.00 49.75  ? 269 PHE C CA  1 
ATOM   7887  C C   . PHE C 3 246 ? 157.531 163.294 178.563 1.00 49.75  ? 269 PHE C C   1 
ATOM   7888  O O   . PHE C 3 246 ? 157.978 162.926 179.654 1.00 49.75  ? 269 PHE C O   1 
ATOM   7889  C CB  . PHE C 3 246 ? 155.410 164.590 178.771 1.00 49.75  ? 269 PHE C CB  1 
ATOM   7890  C CG  . PHE C 3 246 ? 153.938 164.698 178.499 1.00 49.75  ? 269 PHE C CG  1 
ATOM   7891  C CD1 . PHE C 3 246 ? 153.475 164.972 177.223 1.00 49.75  ? 269 PHE C CD1 1 
ATOM   7892  C CD2 . PHE C 3 246 ? 153.018 164.531 179.519 1.00 49.75  ? 269 PHE C CD2 1 
ATOM   7893  C CE1 . PHE C 3 246 ? 152.121 165.074 176.970 1.00 49.75  ? 269 PHE C CE1 1 
ATOM   7894  C CE2 . PHE C 3 246 ? 151.663 164.632 179.273 1.00 49.75  ? 269 PHE C CE2 1 
ATOM   7895  C CZ  . PHE C 3 246 ? 151.214 164.904 177.996 1.00 49.75  ? 269 PHE C CZ  1 
ATOM   7896  N N   . GLN C 3 247 ? 158.299 163.721 177.561 1.00 51.05  ? 270 GLN C N   1 
ATOM   7897  C CA  . GLN C 3 247 ? 159.738 163.961 177.675 1.00 51.05  ? 270 GLN C CA  1 
ATOM   7898  C C   . GLN C 3 247 ? 159.989 165.318 177.023 1.00 51.05  ? 270 GLN C C   1 
ATOM   7899  O O   . GLN C 3 247 ? 160.250 165.402 175.820 1.00 51.05  ? 270 GLN C O   1 
ATOM   7900  C CB  . GLN C 3 247 ? 160.546 162.848 177.016 1.00 51.05  ? 270 GLN C CB  1 
ATOM   7901  C CG  . GLN C 3 247 ? 162.049 162.986 177.184 1.00 51.05  ? 270 GLN C CG  1 
ATOM   7902  C CD  . GLN C 3 247 ? 162.819 161.942 176.401 1.00 51.05  ? 270 GLN C CD  1 
ATOM   7903  O OE1 . GLN C 3 247 ? 162.243 161.189 175.617 1.00 51.05  ? 270 GLN C OE1 1 
ATOM   7904  N NE2 . GLN C 3 247 ? 164.129 161.893 176.610 1.00 51.05  ? 270 GLN C NE2 1 
ATOM   7905  N N   . ASN C 3 248 ? 159.906 166.377 177.821 1.00 54.40  ? 271 ASN C N   1 
ATOM   7906  C CA  . ASN C 3 248 ? 159.915 167.738 177.308 1.00 54.40  ? 271 ASN C CA  1 
ATOM   7907  C C   . ASN C 3 248 ? 161.337 168.243 177.091 1.00 54.40  ? 271 ASN C C   1 
ATOM   7908  O O   . ASN C 3 248 ? 162.274 167.853 177.793 1.00 54.40  ? 271 ASN C O   1 
ATOM   7909  C CB  . ASN C 3 248 ? 159.172 168.672 178.264 1.00 54.40  ? 271 ASN C CB  1 
ATOM   7910  C CG  . ASN C 3 248 ? 157.706 168.309 178.408 1.00 54.40  ? 271 ASN C CG  1 
ATOM   7911  O OD1 . ASN C 3 248 ? 157.114 167.714 177.508 1.00 54.40  ? 271 ASN C OD1 1 
ATOM   7912  N ND2 . ASN C 3 248 ? 157.114 168.666 179.543 1.00 54.40  ? 271 ASN C ND2 1 
ATOM   7913  N N   . TYR C 3 249 ? 161.483 169.122 176.101 1.00 49.62  ? 272 TYR C N   1 
ATOM   7914  C CA  . TYR C 3 249 ? 162.747 169.771 175.775 1.00 49.62  ? 272 TYR C CA  1 
ATOM   7915  C C   . TYR C 3 249 ? 162.542 171.278 175.828 1.00 49.62  ? 272 TYR C C   1 
ATOM   7916  O O   . TYR C 3 249 ? 161.772 171.828 175.034 1.00 49.62  ? 272 TYR C O   1 
ATOM   7917  C CB  . TYR C 3 249 ? 163.244 169.346 174.393 1.00 49.62  ? 272 TYR C CB  1 
ATOM   7918  C CG  . TYR C 3 249 ? 163.952 168.013 174.378 1.00 49.62  ? 272 TYR C CG  1 
ATOM   7919  C CD1 . TYR C 3 249 ? 165.334 167.941 174.475 1.00 49.62  ? 272 TYR C CD1 1 
ATOM   7920  C CD2 . TYR C 3 249 ? 163.240 166.828 174.264 1.00 49.62  ? 272 TYR C CD2 1 
ATOM   7921  C CE1 . TYR C 3 249 ? 165.987 166.726 174.461 1.00 49.62  ? 272 TYR C CE1 1 
ATOM   7922  C CE2 . TYR C 3 249 ? 163.885 165.607 174.249 1.00 49.62  ? 272 TYR C CE2 1 
ATOM   7923  C CZ  . TYR C 3 249 ? 165.259 165.563 174.349 1.00 49.62  ? 272 TYR C CZ  1 
ATOM   7924  O OH  . TYR C 3 249 ? 165.910 164.352 174.336 1.00 49.62  ? 272 TYR C OH  1 
ATOM   7925  N N   . THR C 3 250 ? 163.225 171.939 176.758 1.00 55.91  ? 273 THR C N   1 
ATOM   7926  C CA  . THR C 3 250 ? 163.084 173.373 176.971 1.00 55.91  ? 273 THR C CA  1 
ATOM   7927  C C   . THR C 3 250 ? 164.366 174.089 176.567 1.00 55.91  ? 273 THR C C   1 
ATOM   7928  O O   . THR C 3 250 ? 165.451 173.750 177.051 1.00 55.91  ? 273 THR C O   1 
ATOM   7929  C CB  . THR C 3 250 ? 162.754 173.680 178.434 1.00 55.91  ? 273 THR C CB  1 
ATOM   7930  O OG1 . THR C 3 250 ? 161.528 173.032 178.796 1.00 55.91  ? 273 THR C OG1 1 
ATOM   7931  C CG2 . THR C 3 250 ? 162.606 175.179 178.641 1.00 55.91  ? 273 THR C CG2 1 
ATOM   7932  N N   . LEU C 3 251 ? 164.235 175.081 175.687 1.00 56.98  ? 274 LEU C N   1 
ATOM   7933  C CA  . LEU C 3 251 ? 165.342 175.924 175.243 1.00 56.98  ? 274 LEU C CA  1 
ATOM   7934  C C   . LEU C 3 251 ? 165.028 177.351 175.667 1.00 56.98  ? 274 LEU C C   1 
ATOM   7935  O O   . LEU C 3 251 ? 164.116 177.977 175.116 1.00 56.98  ? 274 LEU C O   1 
ATOM   7936  C CB  . LEU C 3 251 ? 165.531 175.829 173.730 1.00 56.98  ? 274 LEU C CB  1 
ATOM   7937  C CG  . LEU C 3 251 ? 166.654 176.664 173.115 1.00 56.98  ? 274 LEU C CG  1 
ATOM   7938  C CD1 . LEU C 3 251 ? 168.010 176.154 173.569 1.00 56.98  ? 274 LEU C CD1 1 
ATOM   7939  C CD2 . LEU C 3 251 ? 166.555 176.655 171.599 1.00 56.98  ? 274 LEU C CD2 1 
ATOM   7940  N N   . CYS C 3 252 ? 165.771 177.868 176.645 1.00 71.37  ? 275 CYS C N   1 
ATOM   7941  C CA  . CYS C 3 252 ? 165.392 179.113 177.299 1.00 71.37  ? 275 CYS C CA  1 
ATOM   7942  C C   . CYS C 3 252 ? 166.589 180.051 177.317 1.00 71.37  ? 275 CYS C C   1 
ATOM   7943  O O   . CYS C 3 252 ? 167.585 179.781 177.998 1.00 71.37  ? 275 CYS C O   1 
ATOM   7944  C CB  . CYS C 3 252 ? 164.873 178.831 178.716 1.00 71.37  ? 275 CYS C CB  1 
ATOM   7945  S SG  . CYS C 3 252 ? 164.056 180.207 179.570 1.00 71.37  ? 275 CYS C SG  1 
ATOM   7946  N N   . GLU C 3 253 ? 166.490 181.144 176.567 1.00 73.43  ? 276 GLU C N   1 
ATOM   7947  C CA  . GLU C 3 253 ? 167.576 182.101 176.440 1.00 73.43  ? 276 GLU C CA  1 
ATOM   7948  C C   . GLU C 3 253 ? 167.649 182.999 177.672 1.00 73.43  ? 276 GLU C C   1 
ATOM   7949  O O   . GLU C 3 253 ? 166.674 183.178 178.405 1.00 73.43  ? 276 GLU C O   1 
ATOM   7950  C CB  . GLU C 3 253 ? 167.398 182.942 175.175 1.00 73.43  ? 276 GLU C CB  1 
ATOM   7951  C CG  . GLU C 3 253 ? 168.690 183.468 174.578 1.00 73.43  ? 276 GLU C CG  1 
ATOM   7952  C CD  . GLU C 3 253 ? 168.966 184.908 174.960 1.00 73.43  ? 276 GLU C CD  1 
ATOM   7953  O OE1 . GLU C 3 253 ? 168.057 185.560 175.514 1.00 73.43  ? 276 GLU C OE1 1 
ATOM   7954  O OE2 . GLU C 3 253 ? 170.091 185.388 174.706 1.00 73.43  ? 276 GLU C OE2 1 
ATOM   7955  N N   . SER C 3 254 ? 168.834 183.567 177.896 1.00 75.86  ? 277 SER C N   1 
ATOM   7956  C CA  . SER C 3 254 ? 169.085 184.381 179.079 1.00 75.86  ? 277 SER C CA  1 
ATOM   7957  C C   . SER C 3 254 ? 168.791 185.860 178.855 1.00 75.86  ? 277 SER C C   1 
ATOM   7958  O O   . SER C 3 254 ? 168.126 186.487 179.686 1.00 75.86  ? 277 SER C O   1 
ATOM   7959  C CB  . SER C 3 254 ? 170.536 184.206 179.535 1.00 75.86  ? 277 SER C CB  1 
ATOM   7960  O OG  . SER C 3 254 ? 171.428 184.849 178.643 1.00 75.86  ? 277 SER C OG  1 
ATOM   7961  N N   . PHE C 3 255 ? 169.272 186.435 177.750 1.00 79.60  ? 278 PHE C N   1 
ATOM   7962  C CA  . PHE C 3 255 ? 169.117 187.868 177.528 1.00 79.60  ? 278 PHE C CA  1 
ATOM   7963  C C   . PHE C 3 255 ? 167.681 188.265 177.209 1.00 79.60  ? 278 PHE C C   1 
ATOM   7964  O O   . PHE C 3 255 ? 167.355 189.455 177.273 1.00 79.60  ? 278 PHE C O   1 
ATOM   7965  C CB  . PHE C 3 255 ? 170.041 188.332 176.401 1.00 79.60  ? 278 PHE C CB  1 
ATOM   7966  C CG  . PHE C 3 255 ? 171.499 188.288 176.755 1.00 79.60  ? 278 PHE C CG  1 
ATOM   7967  C CD1 . PHE C 3 255 ? 172.126 189.396 177.300 1.00 79.60  ? 278 PHE C CD1 1 
ATOM   7968  C CD2 . PHE C 3 255 ? 172.245 187.142 176.538 1.00 79.60  ? 278 PHE C CD2 1 
ATOM   7969  C CE1 . PHE C 3 255 ? 173.468 189.359 177.627 1.00 79.60  ? 278 PHE C CE1 1 
ATOM   7970  C CE2 . PHE C 3 255 ? 173.586 187.099 176.862 1.00 79.60  ? 278 PHE C CE2 1 
ATOM   7971  C CZ  . PHE C 3 255 ? 174.199 188.209 177.407 1.00 79.60  ? 278 PHE C CZ  1 
ATOM   7972  N N   . SER C 3 256 ? 166.819 187.307 176.866 1.00 79.01  ? 279 SER C N   1 
ATOM   7973  C CA  . SER C 3 256 ? 165.440 187.608 176.512 1.00 79.01  ? 279 SER C CA  1 
ATOM   7974  C C   . SER C 3 256 ? 164.414 186.998 177.455 1.00 79.01  ? 279 SER C C   1 
ATOM   7975  O O   . SER C 3 256 ? 163.280 187.485 177.499 1.00 79.01  ? 279 SER C O   1 
ATOM   7976  C CB  . SER C 3 256 ? 165.141 187.134 175.082 1.00 79.01  ? 279 SER C CB  1 
ATOM   7977  O OG  . SER C 3 256 ? 163.750 186.961 174.884 1.00 79.01  ? 279 SER C OG  1 
ATOM   7978  N N   . LYS C 3 257 ? 164.781 185.957 178.204 1.00 78.79  ? 280 LYS C N   1 
ATOM   7979  C CA  . LYS C 3 257 ? 163.879 185.276 179.133 1.00 78.79  ? 280 LYS C CA  1 
ATOM   7980  C C   . LYS C 3 257 ? 162.626 184.779 178.407 1.00 78.79  ? 280 LYS C C   1 
ATOM   7981  O O   . LYS C 3 257 ? 161.492 185.122 178.749 1.00 78.79  ? 280 LYS C O   1 
ATOM   7982  C CB  . LYS C 3 257 ? 163.513 186.183 180.314 1.00 78.79  ? 280 LYS C CB  1 
ATOM   7983  C CG  . LYS C 3 257 ? 164.664 186.477 181.262 1.00 78.79  ? 280 LYS C CG  1 
ATOM   7984  C CD  . LYS C 3 257 ? 165.355 187.782 180.907 1.00 78.79  ? 280 LYS C CD  1 
ATOM   7985  C CE  . LYS C 3 257 ? 166.412 188.144 181.934 1.00 78.79  ? 280 LYS C CE  1 
ATOM   7986  N NZ  . LYS C 3 257 ? 167.056 189.450 181.629 1.00 78.79  ? 280 LYS C NZ  1 
ATOM   7987  N N   . ARG C 3 258 ? 162.855 183.955 177.388 1.00 78.12  ? 281 ARG C N   1 
ATOM   7988  C CA  . ARG C 3 258 ? 161.783 183.388 176.581 1.00 78.12  ? 281 ARG C CA  1 
ATOM   7989  C C   . ARG C 3 258 ? 162.020 181.898 176.404 1.00 78.12  ? 281 ARG C C   1 
ATOM   7990  O O   . ARG C 3 258 ? 163.098 181.488 175.960 1.00 78.12  ? 281 ARG C O   1 
ATOM   7991  C CB  . ARG C 3 258 ? 161.700 184.067 175.211 1.00 78.12  ? 281 ARG C CB  1 
ATOM   7992  C CG  . ARG C 3 258 ? 160.906 185.356 175.192 1.00 78.12  ? 281 ARG C CG  1 
ATOM   7993  C CD  . ARG C 3 258 ? 160.727 185.834 173.764 1.00 78.12  ? 281 ARG C CD  1 
ATOM   7994  N NE  . ARG C 3 258 ? 160.306 184.743 172.890 1.00 78.12  ? 281 ARG C NE  1 
ATOM   7995  C CZ  . ARG C 3 258 ? 160.268 184.815 171.564 1.00 78.12  ? 281 ARG C CZ  1 
ATOM   7996  N NH1 . ARG C 3 258 ? 160.631 185.931 170.947 1.00 78.12  ? 281 ARG C NH1 1 
ATOM   7997  N NH2 . ARG C 3 258 ? 159.870 183.769 170.854 1.00 78.12  ? 281 ARG C NH2 1 
ATOM   7998  N N   . CYS C 3 259 ? 161.010 181.095 176.736 1.00 77.59  ? 282 CYS C N   1 
ATOM   7999  C CA  . CYS C 3 259 ? 161.108 179.645 176.608 1.00 77.59  ? 282 CYS C CA  1 
ATOM   8000  C C   . CYS C 3 259 ? 159.742 178.993 176.740 1.00 77.59  ? 282 CYS C C   1 
ATOM   8001  O O   . CYS C 3 259 ? 158.946 179.370 177.605 1.00 77.59  ? 282 CYS C O   1 
ATOM   8002  C CB  . CYS C 3 259 ? 162.094 179.070 177.628 1.00 77.59  ? 282 CYS C CB  1 
ATOM   8003  S SG  . CYS C 3 259 ? 162.085 179.784 179.292 1.00 77.59  ? 282 CYS C SG  1 
ATOM   8004  N N   . GLU C 3 260 ? 159.483 178.021 175.867 1.00 78.04  ? 283 GLU C N   1 
ATOM   8005  C CA  . GLU C 3 260 ? 158.236 177.276 175.851 1.00 78.04  ? 283 GLU C CA  1 
ATOM   8006  C C   . GLU C 3 260 ? 158.540 175.841 175.451 1.00 78.04  ? 283 GLU C C   1 
ATOM   8007  O O   . GLU C 3 260 ? 159.600 175.544 174.894 1.00 78.04  ? 283 GLU C O   1 
ATOM   8008  C CB  . GLU C 3 260 ? 157.220 177.904 174.890 1.00 78.04  ? 283 GLU C CB  1 
ATOM   8009  C CG  . GLU C 3 260 ? 157.685 177.948 173.438 1.00 78.04  ? 283 GLU C CG  1 
ATOM   8010  C CD  . GLU C 3 260 ? 158.490 179.193 173.109 1.00 78.04  ? 283 GLU C CD  1 
ATOM   8011  O OE1 . GLU C 3 260 ? 158.836 179.949 174.040 1.00 78.04  ? 283 GLU C OE1 1 
ATOM   8012  O OE2 . GLU C 3 260 ? 158.778 179.416 171.915 1.00 78.04  ? 283 GLU C OE2 1 
ATOM   8013  N N   . VAL C 3 261 ? 157.593 174.948 175.743 1.00 72.88  ? 284 VAL C N   1 
ATOM   8014  C CA  . VAL C 3 261 ? 157.773 173.534 175.435 1.00 72.88  ? 284 VAL C CA  1 
ATOM   8015  C C   . VAL C 3 261 ? 157.729 173.331 173.927 1.00 72.88  ? 284 VAL C C   1 
ATOM   8016  O O   . VAL C 3 261 ? 156.772 173.738 173.256 1.00 72.88  ? 284 VAL C O   1 
ATOM   8017  C CB  . VAL C 3 261 ? 156.704 172.686 176.141 1.00 72.88  ? 284 VAL C CB  1 
ATOM   8018  C CG1 . VAL C 3 261 ? 156.833 171.224 175.741 1.00 72.88  ? 284 VAL C CG1 1 
ATOM   8019  C CG2 . VAL C 3 261 ? 156.815 172.840 177.651 1.00 72.88  ? 284 VAL C CG2 1 
ATOM   8020  N N   . SER C 3 262 ? 158.769 172.701 173.388 1.00 69.26  ? 285 SER C N   1 
ATOM   8021  C CA  . SER C 3 262 ? 158.839 172.434 171.958 1.00 69.26  ? 285 SER C CA  1 
ATOM   8022  C C   . SER C 3 262 ? 157.948 171.256 171.589 1.00 69.26  ? 285 SER C C   1 
ATOM   8023  O O   . SER C 3 262 ? 157.788 170.310 172.365 1.00 69.26  ? 285 SER C O   1 
ATOM   8024  C CB  . SER C 3 262 ? 160.280 172.152 171.537 1.00 69.26  ? 285 SER C CB  1 
ATOM   8025  O OG  . SER C 3 262 ? 160.320 171.415 170.328 1.00 69.26  ? 285 SER C OG  1 
ATOM   8026  N N   . ASN C 3 263 ? 157.368 171.318 170.390 1.00 76.62  ? 286 ASN C N   1 
ATOM   8027  C CA  . ASN C 3 263 ? 156.483 170.263 169.916 1.00 76.62  ? 286 ASN C CA  1 
ATOM   8028  C C   . ASN C 3 263 ? 157.226 169.110 169.256 1.00 76.62  ? 286 ASN C C   1 
ATOM   8029  O O   . ASN C 3 263 ? 156.622 168.056 169.030 1.00 76.62  ? 286 ASN C O   1 
ATOM   8030  C CB  . ASN C 3 263 ? 155.459 170.838 168.934 1.00 76.62  ? 286 ASN C CB  1 
ATOM   8031  C CG  . ASN C 3 263 ? 154.523 171.835 169.586 1.00 76.62  ? 286 ASN C CG  1 
ATOM   8032  O OD1 . ASN C 3 263 ? 154.239 171.749 170.780 1.00 76.62  ? 286 ASN C OD1 1 
ATOM   8033  N ND2 . ASN C 3 263 ? 154.038 172.791 168.802 1.00 76.62  ? 286 ASN C ND2 1 
ATOM   8034  N N   . TYR C 3 264 ? 158.506 169.277 168.942 1.00 75.38  ? 287 TYR C N   1 
ATOM   8035  C CA  . TYR C 3 264 ? 159.310 168.235 168.322 1.00 75.38  ? 287 TYR C CA  1 
ATOM   8036  C C   . TYR C 3 264 ? 160.332 167.700 169.316 1.00 75.38  ? 287 TYR C C   1 
ATOM   8037  O O   . TYR C 3 264 ? 160.508 168.231 170.416 1.00 75.38  ? 287 TYR C O   1 
ATOM   8038  C CB  . TYR C 3 264 ? 160.008 168.761 167.063 1.00 75.38  ? 287 TYR C CB  1 
ATOM   8039  C CG  . TYR C 3 264 ? 159.065 169.048 165.917 1.00 75.38  ? 287 TYR C CG  1 
ATOM   8040  C CD1 . TYR C 3 264 ? 158.733 168.058 165.002 1.00 75.38  ? 287 TYR C CD1 1 
ATOM   8041  C CD2 . TYR C 3 264 ? 158.506 170.308 165.752 1.00 75.38  ? 287 TYR C CD2 1 
ATOM   8042  C CE1 . TYR C 3 264 ? 157.871 168.315 163.953 1.00 75.38  ? 287 TYR C CE1 1 
ATOM   8043  C CE2 . TYR C 3 264 ? 157.643 170.574 164.706 1.00 75.38  ? 287 TYR C CE2 1 
ATOM   8044  C CZ  . TYR C 3 264 ? 157.330 169.574 163.810 1.00 75.38  ? 287 TYR C CZ  1 
ATOM   8045  O OH  . TYR C 3 264 ? 156.471 169.835 162.767 1.00 75.38  ? 287 TYR C OH  1 
ATOM   8046  N N   . ARG C 3 265 ? 161.011 166.628 168.912 1.00 67.60  ? 288 ARG C N   1 
ATOM   8047  C CA  . ARG C 3 265 ? 161.979 165.951 169.766 1.00 67.60  ? 288 ARG C CA  1 
ATOM   8048  C C   . ARG C 3 265 ? 163.420 166.339 169.467 1.00 67.60  ? 288 ARG C C   1 
ATOM   8049  O O   . ARG C 3 265 ? 164.229 166.447 170.393 1.00 67.60  ? 288 ARG C O   1 
ATOM   8050  C CB  . ARG C 3 265 ? 161.827 164.433 169.636 1.00 67.60  ? 288 ARG C CB  1 
ATOM   8051  C CG  . ARG C 3 265 ? 162.169 163.665 170.902 1.00 67.60  ? 288 ARG C CG  1 
ATOM   8052  C CD  . ARG C 3 265 ? 161.840 162.189 170.757 1.00 67.60  ? 288 ARG C CD  1 
ATOM   8053  N NE  . ARG C 3 265 ? 161.720 161.526 172.052 1.00 67.60  ? 288 ARG C NE  1 
ATOM   8054  C CZ  . ARG C 3 265 ? 160.599 161.474 172.763 1.00 67.60  ? 288 ARG C CZ  1 
ATOM   8055  N NH1 . ARG C 3 265 ? 160.582 160.848 173.932 1.00 67.60  ? 288 ARG C NH1 1 
ATOM   8056  N NH2 . ARG C 3 265 ? 159.495 162.049 172.308 1.00 67.60  ? 288 ARG C NH2 1 
ATOM   8057  N N   . ASN C 3 266 ? 163.767 166.551 168.194 1.00 65.35  ? 289 ASN C N   1 
ATOM   8058  C CA  . ASN C 3 266 ? 165.138 166.876 167.816 1.00 65.35  ? 289 ASN C CA  1 
ATOM   8059  C C   . ASN C 3 266 ? 165.214 168.107 166.919 1.00 65.35  ? 289 ASN C C   1 
ATOM   8060  O O   . ASN C 3 266 ? 166.167 168.243 166.146 1.00 65.35  ? 289 ASN C O   1 
ATOM   8061  C CB  . ASN C 3 266 ? 165.806 165.683 167.127 1.00 65.35  ? 289 ASN C CB  1 
ATOM   8062  C CG  . ASN C 3 266 ? 164.950 165.089 166.027 1.00 65.35  ? 289 ASN C CG  1 
ATOM   8063  O OD1 . ASN C 3 266 ? 163.978 165.699 165.581 1.00 65.35  ? 289 ASN C OD1 1 
ATOM   8064  N ND2 . ASN C 3 266 ? 165.309 163.892 165.581 1.00 65.35  ? 289 ASN C ND2 1 
ATOM   8065  N N   . SER C 3 267 ? 164.235 169.005 167.003 1.00 68.53  ? 290 SER C N   1 
ATOM   8066  C CA  . SER C 3 267 ? 164.237 170.206 166.180 1.00 68.53  ? 290 SER C CA  1 
ATOM   8067  C C   . SER C 3 267 ? 163.309 171.236 166.805 1.00 68.53  ? 290 SER C C   1 
ATOM   8068  O O   . SER C 3 267 ? 162.418 170.903 167.589 1.00 68.53  ? 290 SER C O   1 
ATOM   8069  C CB  . SER C 3 267 ? 163.812 169.904 164.739 1.00 68.53  ? 290 SER C CB  1 
ATOM   8070  O OG  . SER C 3 267 ? 163.418 171.087 164.067 1.00 68.53  ? 290 SER C OG  1 
ATOM   8071  N N   . TYR C 3 268 ? 163.533 172.497 166.439 1.00 63.66  ? 291 TYR C N   1 
ATOM   8072  C CA  . TYR C 3 268 ? 162.720 173.606 166.917 1.00 63.66  ? 291 TYR C CA  1 
ATOM   8073  C C   . TYR C 3 268 ? 163.015 174.827 166.061 1.00 63.66  ? 291 TYR C C   1 
ATOM   8074  O O   . TYR C 3 268 ? 164.169 175.069 165.699 1.00 63.66  ? 291 TYR C O   1 
ATOM   8075  C CB  . TYR C 3 268 ? 163.000 173.913 168.394 1.00 63.66  ? 291 TYR C CB  1 
ATOM   8076  C CG  . TYR C 3 268 ? 162.214 175.085 168.935 1.00 63.66  ? 291 TYR C CG  1 
ATOM   8077  C CD1 . TYR C 3 268 ? 162.825 176.311 169.160 1.00 63.66  ? 291 TYR C CD1 1 
ATOM   8078  C CD2 . TYR C 3 268 ? 160.860 174.967 169.218 1.00 63.66  ? 291 TYR C CD2 1 
ATOM   8079  C CE1 . TYR C 3 268 ? 162.110 177.385 169.653 1.00 63.66  ? 291 TYR C CE1 1 
ATOM   8080  C CE2 . TYR C 3 268 ? 160.137 176.035 169.711 1.00 63.66  ? 291 TYR C CE2 1 
ATOM   8081  C CZ  . TYR C 3 268 ? 160.767 177.241 169.927 1.00 63.66  ? 291 TYR C CZ  1 
ATOM   8082  O OH  . TYR C 3 268 ? 160.051 178.308 170.417 1.00 63.66  ? 291 TYR C OH  1 
ATOM   8083  N N   . THR C 3 269 ? 161.971 175.587 165.743 1.00 58.73  ? 292 THR C N   1 
ATOM   8084  C CA  . THR C 3 269 ? 162.084 176.795 164.932 1.00 58.73  ? 292 THR C CA  1 
ATOM   8085  C C   . THR C 3 269 ? 161.893 178.002 165.842 1.00 58.73  ? 292 THR C C   1 
ATOM   8086  O O   . THR C 3 269 ? 160.767 178.310 166.246 1.00 58.73  ? 292 THR C O   1 
ATOM   8087  C CB  . THR C 3 269 ? 161.060 176.794 163.800 1.00 58.73  ? 292 THR C CB  1 
ATOM   8088  O OG1 . THR C 3 269 ? 161.256 175.636 162.978 1.00 58.73  ? 292 THR C OG1 1 
ATOM   8089  C CG2 . THR C 3 269 ? 161.210 178.043 162.947 1.00 58.73  ? 292 THR C CG2 1 
ATOM   8090  N N   . TRP C 3 270 ? 162.990 178.683 166.159 1.00 64.01  ? 293 TRP C N   1 
ATOM   8091  C CA  . TRP C 3 270 ? 162.959 179.830 167.053 1.00 64.01  ? 293 TRP C CA  1 
ATOM   8092  C C   . TRP C 3 270 ? 162.595 181.093 166.286 1.00 64.01  ? 293 TRP C C   1 
ATOM   8093  O O   . TRP C 3 270 ? 163.024 181.288 165.146 1.00 64.01  ? 293 TRP C O   1 
ATOM   8094  C CB  . TRP C 3 270 ? 164.311 180.009 167.745 1.00 64.01  ? 293 TRP C CB  1 
ATOM   8095  C CG  . TRP C 3 270 ? 164.392 181.230 168.611 1.00 64.01  ? 293 TRP C CG  1 
ATOM   8096  C CD1 . TRP C 3 270 ? 164.775 182.483 168.228 1.00 64.01  ? 293 TRP C CD1 1 
ATOM   8097  C CD2 . TRP C 3 270 ? 164.087 181.314 170.008 1.00 64.01  ? 293 TRP C CD2 1 
ATOM   8098  N NE1 . TRP C 3 270 ? 164.724 183.341 169.299 1.00 64.01  ? 293 TRP C NE1 1 
ATOM   8099  C CE2 . TRP C 3 270 ? 164.305 182.648 170.404 1.00 64.01  ? 293 TRP C CE2 1 
ATOM   8100  C CE3 . TRP C 3 270 ? 163.649 180.390 170.962 1.00 64.01  ? 293 TRP C CE3 1 
ATOM   8101  C CZ2 . TRP C 3 270 ? 164.101 183.081 171.712 1.00 64.01  ? 293 TRP C CZ2 1 
ATOM   8102  C CZ3 . TRP C 3 270 ? 163.447 180.823 172.260 1.00 64.01  ? 293 TRP C CZ3 1 
ATOM   8103  C CH2 . TRP C 3 270 ? 163.673 182.156 172.623 1.00 64.01  ? 293 TRP C CH2 1 
ATOM   8104  N N   . GLN C 3 271 ? 161.798 181.948 166.920 1.00 70.85  ? 294 GLN C N   1 
ATOM   8105  C CA  . GLN C 3 271 ? 161.403 183.234 166.360 1.00 70.85  ? 294 GLN C CA  1 
ATOM   8106  C C   . GLN C 3 271 ? 162.094 184.339 167.146 1.00 70.85  ? 294 GLN C C   1 
ATOM   8107  O O   . GLN C 3 271 ? 161.904 184.453 168.361 1.00 70.85  ? 294 GLN C O   1 
ATOM   8108  C CB  . GLN C 3 271 ? 159.885 183.408 166.404 1.00 70.85  ? 294 GLN C CB  1 
ATOM   8109  C CG  . GLN C 3 271 ? 159.124 182.458 165.496 1.00 70.85  ? 294 GLN C CG  1 
ATOM   8110  C CD  . GLN C 3 271 ? 159.271 182.813 164.030 1.00 70.85  ? 294 GLN C CD  1 
ATOM   8111  O OE1 . GLN C 3 271 ? 159.628 183.939 163.684 1.00 70.85  ? 294 GLN C OE1 1 
ATOM   8112  N NE2 . GLN C 3 271 ? 158.996 181.850 163.158 1.00 70.85  ? 294 GLN C NE2 1 
ATOM   8113  N N   . ILE C 3 272 ? 162.890 185.145 166.455 1.00 83.51  ? 295 ILE C N   1 
ATOM   8114  C CA  . ILE C 3 272 ? 163.646 186.221 167.086 1.00 83.51  ? 295 ILE C CA  1 
ATOM   8115  C C   . ILE C 3 272 ? 162.840 187.509 167.014 1.00 83.51  ? 295 ILE C C   1 
ATOM   8116  O O   . ILE C 3 272 ? 162.212 187.815 165.992 1.00 83.51  ? 295 ILE C O   1 
ATOM   8117  C CB  . ILE C 3 272 ? 165.029 186.380 166.424 1.00 83.51  ? 295 ILE C CB  1 
ATOM   8118  C CG1 . ILE C 3 272 ? 165.795 187.555 167.038 1.00 83.51  ? 295 ILE C CG1 1 
ATOM   8119  C CG2 . ILE C 3 272 ? 164.893 186.547 164.917 1.00 83.51  ? 295 ILE C CG2 1 
ATOM   8120  C CD1 . ILE C 3 272 ? 166.058 187.408 168.521 1.00 83.51  ? 295 ILE C CD1 1 
ATOM   8121  N N   . THR C 3 273 ? 162.844 188.263 168.109 1.00 94.19  ? 296 THR C N   1 
ATOM   8122  C CA  . THR C 3 273 ? 162.169 189.549 168.148 1.00 94.19  ? 296 THR C CA  1 
ATOM   8123  C C   . THR C 3 273 ? 163.055 190.633 167.545 1.00 94.19  ? 296 THR C C   1 
ATOM   8124  O O   . THR C 3 273 ? 164.284 190.522 167.523 1.00 94.19  ? 296 THR C O   1 
ATOM   8125  C CB  . THR C 3 273 ? 161.798 189.924 169.583 1.00 94.19  ? 296 THR C CB  1 
ATOM   8126  O OG1 . THR C 3 273 ? 162.887 189.608 170.459 1.00 94.19  ? 296 THR C OG1 1 
ATOM   8127  C CG2 . THR C 3 273 ? 160.559 189.163 170.028 1.00 94.19  ? 296 THR C CG2 1 
ATOM   8128  N N   . GLU C 3 274 ? 162.414 191.688 167.049 1.00 105.84 ? 297 GLU C N   1 
ATOM   8129  C CA  . GLU C 3 274 ? 163.144 192.789 166.444 1.00 105.84 ? 297 GLU C CA  1 
ATOM   8130  C C   . GLU C 3 274 ? 163.960 193.536 167.496 1.00 105.84 ? 297 GLU C C   1 
ATOM   8131  O O   . GLU C 3 274 ? 163.692 193.466 168.699 1.00 105.84 ? 297 GLU C O   1 
ATOM   8132  C CB  . GLU C 3 274 ? 162.181 193.748 165.744 1.00 105.84 ? 297 GLU C CB  1 
ATOM   8133  C CG  . GLU C 3 274 ? 161.230 193.070 164.771 1.00 105.84 ? 297 GLU C CG  1 
ATOM   8134  C CD  . GLU C 3 274 ? 161.942 192.490 163.565 1.00 105.84 ? 297 GLU C CD  1 
ATOM   8135  O OE1 . GLU C 3 274 ? 163.011 193.018 163.191 1.00 105.84 ? 297 GLU C OE1 1 
ATOM   8136  O OE2 . GLU C 3 274 ? 161.434 191.503 162.991 1.00 105.84 ? 297 GLU C OE2 1 
ATOM   8137  N N   . GLY C 3 275 ? 164.972 194.258 167.024 1.00 108.79 ? 298 GLY C N   1 
ATOM   8138  C CA  . GLY C 3 275 ? 165.838 195.012 167.909 1.00 108.79 ? 298 GLY C CA  1 
ATOM   8139  C C   . GLY C 3 275 ? 167.290 194.976 167.483 1.00 108.79 ? 298 GLY C C   1 
ATOM   8140  O O   . GLY C 3 275 ? 168.124 195.700 168.037 1.00 108.79 ? 298 GLY C O   1 
ATOM   8141  N N   . SER C 3 276 ? 167.597 194.137 166.492 1.00 104.91 ? 299 SER C N   1 
ATOM   8142  C CA  . SER C 3 276 ? 168.956 193.980 165.965 1.00 104.91 ? 299 SER C CA  1 
ATOM   8143  C C   . SER C 3 276 ? 169.948 193.631 167.074 1.00 104.91 ? 299 SER C C   1 
ATOM   8144  O O   . SER C 3 276 ? 171.074 194.130 167.106 1.00 104.91 ? 299 SER C O   1 
ATOM   8145  C CB  . SER C 3 276 ? 169.409 195.228 165.202 1.00 104.91 ? 299 SER C CB  1 
ATOM   8146  O OG  . SER C 3 276 ? 169.441 196.370 166.040 1.00 104.91 ? 299 SER C OG  1 
ATOM   8147  N N   . GLN C 3 277 ? 169.525 192.765 167.991 1.00 96.40  ? 300 GLN C N   1 
ATOM   8148  C CA  . GLN C 3 277 ? 170.394 192.313 169.068 1.00 96.40  ? 300 GLN C CA  1 
ATOM   8149  C C   . GLN C 3 277 ? 171.268 191.166 168.577 1.00 96.40  ? 300 GLN C C   1 
ATOM   8150  O O   . GLN C 3 277 ? 170.758 190.137 168.123 1.00 96.40  ? 300 GLN C O   1 
ATOM   8151  C CB  . GLN C 3 277 ? 169.565 191.872 170.274 1.00 96.40  ? 300 GLN C CB  1 
ATOM   8152  C CG  . GLN C 3 277 ? 170.385 191.298 171.418 1.00 96.40  ? 300 GLN C CG  1 
ATOM   8153  C CD  . GLN C 3 277 ? 171.147 192.362 172.182 1.00 96.40  ? 300 GLN C CD  1 
ATOM   8154  O OE1 . GLN C 3 277 ? 172.207 192.097 172.749 1.00 96.40  ? 300 GLN C OE1 1 
ATOM   8155  N NE2 . GLN C 3 277 ? 170.609 193.576 172.203 1.00 96.40  ? 300 GLN C NE2 1 
ATOM   8156  N N   . GLU C 3 278 ? 172.584 191.341 168.673 1.00 94.70  ? 301 GLU C N   1 
ATOM   8157  C CA  . GLU C 3 278 ? 173.545 190.348 168.201 1.00 94.70  ? 301 GLU C CA  1 
ATOM   8158  C C   . GLU C 3 278 ? 174.262 189.759 169.413 1.00 94.70  ? 301 GLU C C   1 
ATOM   8159  O O   . GLU C 3 278 ? 175.361 190.177 169.780 1.00 94.70  ? 301 GLU C O   1 
ATOM   8160  C CB  . GLU C 3 278 ? 174.529 190.977 167.210 1.00 94.70  ? 301 GLU C CB  1 
ATOM   8161  C CG  . GLU C 3 278 ? 173.867 191.684 166.036 1.00 94.70  ? 301 GLU C CG  1 
ATOM   8162  C CD  . GLU C 3 278 ? 172.944 190.774 165.248 1.00 94.70  ? 301 GLU C CD  1 
ATOM   8163  O OE1 . GLU C 3 278 ? 171.723 190.792 165.508 1.00 94.70  ? 301 GLU C OE1 1 
ATOM   8164  O OE2 . GLU C 3 278 ? 173.441 190.041 164.368 1.00 94.70  ? 301 GLU C OE2 1 
ATOM   8165  N N   . MET C 3 279 ? 173.625 188.764 170.025 1.00 84.17  ? 302 MET C N   1 
ATOM   8166  C CA  . MET C 3 279 ? 174.168 187.995 171.137 1.00 84.17  ? 302 MET C CA  1 
ATOM   8167  C C   . MET C 3 279 ? 173.189 186.874 171.446 1.00 84.17  ? 302 MET C C   1 
ATOM   8168  O O   . MET C 3 279 ? 171.974 187.049 171.312 1.00 84.17  ? 302 MET C O   1 
ATOM   8169  C CB  . MET C 3 279 ? 174.394 188.863 172.381 1.00 84.17  ? 302 MET C CB  1 
ATOM   8170  C CG  . MET C 3 279 ? 175.245 188.201 173.452 1.00 84.17  ? 302 MET C CG  1 
ATOM   8171  S SD  . MET C 3 279 ? 176.885 187.752 172.856 1.00 84.17  ? 302 MET C SD  1 
ATOM   8172  C CE  . MET C 3 279 ? 177.524 189.356 172.384 1.00 84.17  ? 302 MET C CE  1 
ATOM   8173  N N   . TYR C 3 280 ? 173.722 185.730 171.867 1.00 70.81  ? 303 TYR C N   1 
ATOM   8174  C CA  . TYR C 3 280 ? 172.881 184.580 172.167 1.00 70.81  ? 303 TYR C CA  1 
ATOM   8175  C C   . TYR C 3 280 ? 173.548 183.721 173.228 1.00 70.81  ? 303 TYR C C   1 
ATOM   8176  O O   . TYR C 3 280 ? 174.750 183.452 173.150 1.00 70.81  ? 303 TYR C O   1 
ATOM   8177  C CB  . TYR C 3 280 ? 172.605 183.754 170.906 1.00 70.81  ? 303 TYR C CB  1 
ATOM   8178  C CG  . TYR C 3 280 ? 171.611 184.402 169.971 1.00 70.81  ? 303 TYR C CG  1 
ATOM   8179  C CD1 . TYR C 3 280 ? 170.250 184.377 170.247 1.00 70.81  ? 303 TYR C CD1 1 
ATOM   8180  C CD2 . TYR C 3 280 ? 172.032 185.050 168.818 1.00 70.81  ? 303 TYR C CD2 1 
ATOM   8181  C CE1 . TYR C 3 280 ? 169.338 184.972 169.398 1.00 70.81  ? 303 TYR C CE1 1 
ATOM   8182  C CE2 . TYR C 3 280 ? 171.127 185.648 167.964 1.00 70.81  ? 303 TYR C CE2 1 
ATOM   8183  C CZ  . TYR C 3 280 ? 169.782 185.606 168.258 1.00 70.81  ? 303 TYR C CZ  1 
ATOM   8184  O OH  . TYR C 3 280 ? 168.879 186.200 167.409 1.00 70.81  ? 303 TYR C OH  1 
ATOM   8185  N N   . ASN C 3 281 ? 172.759 183.296 174.216 1.00 69.77  ? 304 ASN C N   1 
ATOM   8186  C CA  . ASN C 3 281 ? 173.239 182.432 175.295 1.00 69.77  ? 304 ASN C CA  1 
ATOM   8187  C C   . ASN C 3 281 ? 172.069 181.527 175.688 1.00 69.77  ? 304 ASN C C   1 
ATOM   8188  O O   . ASN C 3 281 ? 171.237 181.894 176.520 1.00 69.77  ? 304 ASN C O   1 
ATOM   8189  C CB  . ASN C 3 281 ? 173.746 183.249 176.474 1.00 69.77  ? 304 ASN C CB  1 
ATOM   8190  C CG  . ASN C 3 281 ? 174.260 182.387 177.608 1.00 69.77  ? 304 ASN C CG  1 
ATOM   8191  O OD1 . ASN C 3 281 ? 174.648 181.237 177.405 1.00 69.77  ? 304 ASN C OD1 1 
ATOM   8192  N ND2 . ASN C 3 281 ? 174.266 182.943 178.813 1.00 69.77  ? 304 ASN C ND2 1 
ATOM   8193  N N   . PHE C 3 282 ? 172.023 180.347 175.082 1.00 60.37  ? 305 PHE C N   1 
ATOM   8194  C CA  . PHE C 3 282 ? 170.910 179.425 175.248 1.00 60.37  ? 305 PHE C CA  1 
ATOM   8195  C C   . PHE C 3 282 ? 171.227 178.372 176.303 1.00 60.37  ? 305 PHE C C   1 
ATOM   8196  O O   . PHE C 3 282 ? 172.368 178.205 176.737 1.00 60.37  ? 305 PHE C O   1 
ATOM   8197  C CB  . PHE C 3 282 ? 170.567 178.754 173.915 1.00 60.37  ? 305 PHE C CB  1 
ATOM   8198  C CG  . PHE C 3 282 ? 169.859 179.656 172.947 1.00 60.37  ? 305 PHE C CG  1 
ATOM   8199  C CD1 . PHE C 3 282 ? 168.516 179.951 173.109 1.00 60.37  ? 305 PHE C CD1 1 
ATOM   8200  C CD2 . PHE C 3 282 ? 170.535 180.205 171.872 1.00 60.37  ? 305 PHE C CD2 1 
ATOM   8201  C CE1 . PHE C 3 282 ? 167.862 180.780 172.219 1.00 60.37  ? 305 PHE C CE1 1 
ATOM   8202  C CE2 . PHE C 3 282 ? 169.885 181.034 170.978 1.00 60.37  ? 305 PHE C CE2 1 
ATOM   8203  C CZ  . PHE C 3 282 ? 168.547 181.322 171.152 1.00 60.37  ? 305 PHE C CZ  1 
ATOM   8204  N N   . THR C 3 283 ? 170.181 177.656 176.718 1.00 55.17  ? 306 THR C N   1 
ATOM   8205  C CA  . THR C 3 283 ? 170.324 176.575 177.693 1.00 55.17  ? 306 THR C CA  1 
ATOM   8206  C C   . THR C 3 283 ? 169.224 175.556 177.409 1.00 55.17  ? 306 THR C C   1 
ATOM   8207  O O   . THR C 3 283 ? 168.084 175.732 177.849 1.00 55.17  ? 306 THR C O   1 
ATOM   8208  C CB  . THR C 3 283 ? 170.241 177.101 179.120 1.00 55.17  ? 306 THR C CB  1 
ATOM   8209  O OG1 . THR C 3 283 ? 171.258 178.090 179.327 1.00 55.17  ? 306 THR C OG1 1 
ATOM   8210  C CG2 . THR C 3 283 ? 170.438 175.968 180.116 1.00 55.17  ? 306 THR C CG2 1 
ATOM   8211  N N   . LEU C 3 284 ? 169.571 174.502 176.675 1.00 52.54  ? 307 LEU C N   1 
ATOM   8212  C CA  . LEU C 3 284 ? 168.621 173.439 176.377 1.00 52.54  ? 307 LEU C CA  1 
ATOM   8213  C C   . LEU C 3 284 ? 168.490 172.514 177.580 1.00 52.54  ? 307 LEU C C   1 
ATOM   8214  O O   . LEU C 3 284 ? 169.493 172.126 178.186 1.00 52.54  ? 307 LEU C O   1 
ATOM   8215  C CB  . LEU C 3 284 ? 169.067 172.653 175.146 1.00 52.54  ? 307 LEU C CB  1 
ATOM   8216  C CG  . LEU C 3 284 ? 168.188 171.465 174.754 1.00 52.54  ? 307 LEU C CG  1 
ATOM   8217  C CD1 . LEU C 3 284 ? 166.757 171.915 174.517 1.00 52.54  ? 307 LEU C CD1 1 
ATOM   8218  C CD2 . LEU C 3 284 ? 168.745 170.770 173.523 1.00 52.54  ? 307 LEU C CD2 1 
ATOM   8219  N N   . THR C 3 285 ? 167.253 172.162 177.925 1.00 52.03  ? 308 THR C N   1 
ATOM   8220  C CA  . THR C 3 285 ? 166.974 171.351 179.102 1.00 52.03  ? 308 THR C CA  1 
ATOM   8221  C C   . THR C 3 285 ? 165.994 170.244 178.744 1.00 52.03  ? 308 THR C C   1 
ATOM   8222  O O   . THR C 3 285 ? 164.911 170.516 178.218 1.00 52.03  ? 308 THR C O   1 
ATOM   8223  C CB  . THR C 3 285 ? 166.407 172.205 180.241 1.00 52.03  ? 308 THR C CB  1 
ATOM   8224  O OG1 . THR C 3 285 ? 167.413 173.114 180.705 1.00 52.03  ? 308 THR C OG1 1 
ATOM   8225  C CG2 . THR C 3 285 ? 165.956 171.324 181.395 1.00 52.03  ? 308 THR C CG2 1 
ATOM   8226  N N   . ALA C 3 286 ? 166.377 169.003 179.032 1.00 52.99  ? 309 ALA C N   1 
ATOM   8227  C CA  . ALA C 3 286 ? 165.516 167.841 178.859 1.00 52.99  ? 309 ALA C CA  1 
ATOM   8228  C C   . ALA C 3 286 ? 165.155 167.304 180.236 1.00 52.99  ? 309 ALA C C   1 
ATOM   8229  O O   . ALA C 3 286 ? 166.044 167.002 181.039 1.00 52.99  ? 309 ALA C O   1 
ATOM   8230  C CB  . ALA C 3 286 ? 166.204 166.764 178.021 1.00 52.99  ? 309 ALA C CB  1 
ATOM   8231  N N   . GLU C 3 287 ? 163.857 167.185 180.507 1.00 66.33  ? 310 GLU C N   1 
ATOM   8232  C CA  . GLU C 3 287 ? 163.385 166.802 181.829 1.00 66.33  ? 310 GLU C CA  1 
ATOM   8233  C C   . GLU C 3 287 ? 162.289 165.754 181.713 1.00 66.33  ? 310 GLU C C   1 
ATOM   8234  O O   . GLU C 3 287 ? 161.420 165.843 180.842 1.00 66.33  ? 310 GLU C O   1 
ATOM   8235  C CB  . GLU C 3 287 ? 162.859 168.018 182.603 1.00 66.33  ? 310 GLU C CB  1 
ATOM   8236  C CG  . GLU C 3 287 ? 162.509 167.731 184.054 1.00 66.33  ? 310 GLU C CG  1 
ATOM   8237  C CD  . GLU C 3 287 ? 161.813 168.897 184.727 1.00 66.33  ? 310 GLU C CD  1 
ATOM   8238  O OE1 . GLU C 3 287 ? 160.983 169.557 184.067 1.00 66.33  ? 310 GLU C OE1 1 
ATOM   8239  O OE2 . GLU C 3 287 ? 162.096 169.154 185.916 1.00 66.33  ? 310 GLU C OE2 1 
ATOM   8240  N N   . ASN C 3 288 ? 162.342 164.760 182.600 1.00 57.92  ? 311 ASN C N   1 
ATOM   8241  C CA  . ASN C 3 288 ? 161.277 163.773 182.724 1.00 57.92  ? 311 ASN C CA  1 
ATOM   8242  C C   . ASN C 3 288 ? 160.816 163.703 184.174 1.00 57.92  ? 311 ASN C C   1 
ATOM   8243  O O   . ASN C 3 288 ? 161.196 164.548 184.990 1.00 57.92  ? 311 ASN C O   1 
ATOM   8244  C CB  . ASN C 3 288 ? 161.740 162.399 182.234 1.00 57.92  ? 311 ASN C CB  1 
ATOM   8245  C CG  . ASN C 3 288 ? 163.055 161.968 182.851 1.00 57.92  ? 311 ASN C CG  1 
ATOM   8246  O OD1 . ASN C 3 288 ? 163.577 162.620 183.755 1.00 57.92  ? 311 ASN C OD1 1 
ATOM   8247  N ND2 . ASN C 3 288 ? 163.599 160.858 182.365 1.00 57.92  ? 311 ASN C ND2 1 
ATOM   8248  N N   . GLN C 3 289 ? 159.997 162.704 184.507 1.00 53.77  ? 312 GLN C N   1 
ATOM   8249  C CA  . GLN C 3 289 ? 159.488 162.583 185.868 1.00 53.77  ? 312 GLN C CA  1 
ATOM   8250  C C   . GLN C 3 289 ? 160.554 162.160 186.871 1.00 53.77  ? 312 GLN C C   1 
ATOM   8251  O O   . GLN C 3 289 ? 160.280 162.174 188.076 1.00 53.77  ? 312 GLN C O   1 
ATOM   8252  C CB  . GLN C 3 289 ? 158.329 161.586 185.907 1.00 53.77  ? 312 GLN C CB  1 
ATOM   8253  C CG  . GLN C 3 289 ? 157.095 162.036 185.146 1.00 53.77  ? 312 GLN C CG  1 
ATOM   8254  C CD  . GLN C 3 289 ? 155.931 161.079 185.310 1.00 53.77  ? 312 GLN C CD  1 
ATOM   8255  O OE1 . GLN C 3 289 ? 156.036 160.071 186.008 1.00 53.77  ? 312 GLN C OE1 1 
ATOM   8256  N NE2 . GLN C 3 289 ? 154.813 161.391 184.665 1.00 53.77  ? 312 GLN C NE2 1 
ATOM   8257  N N   . LEU C 3 290 ? 161.751 161.791 186.417 1.00 53.02  ? 313 LEU C N   1 
ATOM   8258  C CA  . LEU C 3 290 ? 162.806 161.309 187.299 1.00 53.02  ? 313 LEU C CA  1 
ATOM   8259  C C   . LEU C 3 290 ? 163.940 162.305 187.485 1.00 53.02  ? 313 LEU C C   1 
ATOM   8260  O O   . LEU C 3 290 ? 164.276 162.651 188.621 1.00 53.02  ? 313 LEU C O   1 
ATOM   8261  C CB  . LEU C 3 290 ? 163.365 159.981 186.769 1.00 53.02  ? 313 LEU C CB  1 
ATOM   8262  C CG  . LEU C 3 290 ? 162.413 158.787 186.835 1.00 53.02  ? 313 LEU C CG  1 
ATOM   8263  C CD1 . LEU C 3 290 ? 163.079 157.542 186.277 1.00 53.02  ? 313 LEU C CD1 1 
ATOM   8264  C CD2 . LEU C 3 290 ? 161.949 158.555 188.263 1.00 53.02  ? 313 LEU C CD2 1 
ATOM   8265  N N   . ARG C 3 291 ? 164.544 162.779 186.398 1.00 54.12  ? 314 ARG C N   1 
ATOM   8266  C CA  . ARG C 3 291 ? 165.720 163.636 186.483 1.00 54.12  ? 314 ARG C CA  1 
ATOM   8267  C C   . ARG C 3 291 ? 165.548 164.802 185.516 1.00 54.12  ? 314 ARG C C   1 
ATOM   8268  O O   . ARG C 3 291 ? 164.470 165.016 184.953 1.00 54.12  ? 314 ARG C O   1 
ATOM   8269  C CB  . ARG C 3 291 ? 166.996 162.833 186.200 1.00 54.12  ? 314 ARG C CB  1 
ATOM   8270  C CG  . ARG C 3 291 ? 166.964 162.058 184.894 1.00 54.12  ? 314 ARG C CG  1 
ATOM   8271  C CD  . ARG C 3 291 ? 168.340 161.519 184.532 1.00 54.12  ? 314 ARG C CD  1 
ATOM   8272  N NE  . ARG C 3 291 ? 168.883 160.645 185.569 1.00 54.12  ? 314 ARG C NE  1 
ATOM   8273  C CZ  . ARG C 3 291 ? 169.872 160.983 186.390 1.00 54.12  ? 314 ARG C CZ  1 
ATOM   8274  N NH1 . ARG C 3 291 ? 170.432 162.182 186.297 1.00 54.12  ? 314 ARG C NH1 1 
ATOM   8275  N NH2 . ARG C 3 291 ? 170.301 160.124 187.303 1.00 54.12  ? 314 ARG C NH2 1 
ATOM   8276  N N   . LYS C 3 292 ? 166.625 165.563 185.324 1.00 52.52  ? 315 LYS C N   1 
ATOM   8277  C CA  . LYS C 3 292 ? 166.578 166.758 184.485 1.00 52.52  ? 315 LYS C CA  1 
ATOM   8278  C C   . LYS C 3 292 ? 167.994 167.068 184.018 1.00 52.52  ? 315 LYS C C   1 
ATOM   8279  O O   . LYS C 3 292 ? 168.854 167.405 184.836 1.00 52.52  ? 315 LYS C O   1 
ATOM   8280  C CB  . LYS C 3 292 ? 165.979 167.930 185.255 1.00 52.52  ? 315 LYS C CB  1 
ATOM   8281  C CG  . LYS C 3 292 ? 166.231 169.291 184.631 1.00 52.52  ? 315 LYS C CG  1 
ATOM   8282  C CD  . LYS C 3 292 ? 165.797 170.405 185.570 1.00 52.52  ? 315 LYS C CD  1 
ATOM   8283  C CE  . LYS C 3 292 ? 166.212 171.769 185.045 1.00 52.52  ? 315 LYS C CE  1 
ATOM   8284  N NZ  . LYS C 3 292 ? 165.860 172.858 185.997 1.00 52.52  ? 315 LYS C NZ  1 
ATOM   8285  N N   . ARG C 3 293 ? 168.230 166.952 182.715 1.00 53.94  ? 316 ARG C N   1 
ATOM   8286  C CA  . ARG C 3 293 ? 169.522 167.253 182.118 1.00 53.94  ? 316 ARG C CA  1 
ATOM   8287  C C   . ARG C 3 293 ? 169.481 168.613 181.434 1.00 53.94  ? 316 ARG C C   1 
ATOM   8288  O O   . ARG C 3 293 ? 168.432 169.061 180.963 1.00 53.94  ? 316 ARG C O   1 
ATOM   8289  C CB  . ARG C 3 293 ? 169.922 166.175 181.109 1.00 53.94  ? 316 ARG C CB  1 
ATOM   8290  C CG  . ARG C 3 293 ? 170.284 164.840 181.736 1.00 53.94  ? 316 ARG C CG  1 
ATOM   8291  C CD  . ARG C 3 293 ? 171.526 164.955 182.601 1.00 53.94  ? 316 ARG C CD  1 
ATOM   8292  N NE  . ARG C 3 293 ? 171.851 163.693 183.258 1.00 53.94  ? 316 ARG C NE  1 
ATOM   8293  C CZ  . ARG C 3 293 ? 172.582 162.730 182.706 1.00 53.94  ? 316 ARG C CZ  1 
ATOM   8294  N NH1 . ARG C 3 293 ? 173.066 162.882 181.481 1.00 53.94  ? 316 ARG C NH1 1 
ATOM   8295  N NH2 . ARG C 3 293 ? 172.827 161.613 183.377 1.00 53.94  ? 316 ARG C NH2 1 
ATOM   8296  N N   . SER C 3 294 ? 170.638 169.269 181.379 1.00 48.57  ? 317 SER C N   1 
ATOM   8297  C CA  . SER C 3 294 ? 170.730 170.604 180.808 1.00 48.57  ? 317 SER C CA  1 
ATOM   8298  C C   . SER C 3 294 ? 172.076 170.773 180.120 1.00 48.57  ? 317 SER C C   1 
ATOM   8299  O O   . SER C 3 294 ? 173.094 170.264 180.596 1.00 48.57  ? 317 SER C O   1 
ATOM   8300  C CB  . SER C 3 294 ? 170.547 171.683 181.880 1.00 48.57  ? 317 SER C CB  1 
ATOM   8301  O OG  . SER C 3 294 ? 171.114 172.913 181.465 1.00 48.57  ? 317 SER C OG  1 
ATOM   8302  N N   . VAL C 3 295 ? 172.070 171.493 179.001 1.00 49.44  ? 318 VAL C N   1 
ATOM   8303  C CA  . VAL C 3 295 ? 173.276 171.779 178.233 1.00 49.44  ? 318 VAL C CA  1 
ATOM   8304  C C   . VAL C 3 295 ? 173.209 173.225 177.759 1.00 49.44  ? 318 VAL C C   1 
ATOM   8305  O O   . VAL C 3 295 ? 172.143 173.713 177.369 1.00 49.44  ? 318 VAL C O   1 
ATOM   8306  C CB  . VAL C 3 295 ? 173.438 170.803 177.047 1.00 49.44  ? 318 VAL C CB  1 
ATOM   8307  C CG1 . VAL C 3 295 ? 172.190 170.800 176.176 1.00 49.44  ? 318 VAL C CG1 1 
ATOM   8308  C CG2 . VAL C 3 295 ? 174.674 171.144 176.226 1.00 49.44  ? 318 VAL C CG2 1 
ATOM   8309  N N   . ASN C 3 296 ? 174.347 173.914 177.804 1.00 56.46  ? 319 ASN C N   1 
ATOM   8310  C CA  . ASN C 3 296 ? 174.432 175.322 177.445 1.00 56.46  ? 319 ASN C CA  1 
ATOM   8311  C C   . ASN C 3 296 ? 175.324 175.499 176.225 1.00 56.46  ? 319 ASN C C   1 
ATOM   8312  O O   . ASN C 3 296 ? 176.392 174.886 176.130 1.00 56.46  ? 319 ASN C O   1 
ATOM   8313  C CB  . ASN C 3 296 ? 174.975 176.155 178.610 1.00 56.46  ? 319 ASN C CB  1 
ATOM   8314  C CG  . ASN C 3 296 ? 175.522 177.495 178.162 1.00 56.46  ? 319 ASN C CG  1 
ATOM   8315  O OD1 . ASN C 3 296 ? 176.731 177.662 177.998 1.00 56.46  ? 319 ASN C OD1 1 
ATOM   8316  N ND2 . ASN C 3 296 ? 174.633 178.459 177.958 1.00 56.46  ? 319 ASN C ND2 1 
ATOM   8317  N N   . ILE C 3 297 ? 174.880 176.345 175.294 1.00 59.29  ? 320 ILE C N   1 
ATOM   8318  C CA  . ILE C 3 297 ? 175.636 176.666 174.093 1.00 59.29  ? 320 ILE C CA  1 
ATOM   8319  C C   . ILE C 3 297 ? 175.775 178.179 173.996 1.00 59.29  ? 320 ILE C C   1 
ATOM   8320  O O   . ILE C 3 297 ? 175.010 178.939 174.594 1.00 59.29  ? 320 ILE C O   1 
ATOM   8321  C CB  . ILE C 3 297 ? 174.981 176.105 172.813 1.00 59.29  ? 320 ILE C CB  1 
ATOM   8322  C CG1 . ILE C 3 297 ? 173.594 176.717 172.609 1.00 59.29  ? 320 ILE C CG1 1 
ATOM   8323  C CG2 . ILE C 3 297 ? 174.897 174.589 172.875 1.00 59.29  ? 320 ILE C CG2 1 
ATOM   8324  C CD1 . ILE C 3 297 ? 172.893 176.237 171.359 1.00 59.29  ? 320 ILE C CD1 1 
ATOM   8325  N N   . ASN C 3 298 ? 176.772 178.611 173.227 1.00 64.82  ? 321 ASN C N   1 
ATOM   8326  C CA  . ASN C 3 298 ? 177.046 180.027 173.031 1.00 64.82  ? 321 ASN C CA  1 
ATOM   8327  C C   . ASN C 3 298 ? 177.548 180.243 171.613 1.00 64.82  ? 321 ASN C C   1 
ATOM   8328  O O   . ASN C 3 298 ? 178.515 179.601 171.192 1.00 64.82  ? 321 ASN C O   1 
ATOM   8329  C CB  . ASN C 3 298 ? 178.078 180.540 174.042 1.00 64.82  ? 321 ASN C CB  1 
ATOM   8330  C CG  . ASN C 3 298 ? 178.408 182.005 173.845 1.00 64.82  ? 321 ASN C CG  1 
ATOM   8331  O OD1 . ASN C 3 298 ? 177.593 182.775 173.339 1.00 64.82  ? 321 ASN C OD1 1 
ATOM   8332  N ND2 . ASN C 3 298 ? 179.612 182.398 174.244 1.00 64.82  ? 321 ASN C ND2 1 
ATOM   8333  N N   . PHE C 3 299 ? 176.894 181.144 170.884 1.00 65.86  ? 322 PHE C N   1 
ATOM   8334  C CA  . PHE C 3 299 ? 177.264 181.431 169.506 1.00 65.86  ? 322 PHE C CA  1 
ATOM   8335  C C   . PHE C 3 299 ? 176.898 182.875 169.189 1.00 65.86  ? 322 PHE C C   1 
ATOM   8336  O O   . PHE C 3 299 ? 176.374 183.607 170.033 1.00 65.86  ? 322 PHE C O   1 
ATOM   8337  C CB  . PHE C 3 299 ? 176.586 180.455 168.539 1.00 65.86  ? 322 PHE C CB  1 
ATOM   8338  C CG  . PHE C 3 299 ? 175.101 180.652 168.414 1.00 65.86  ? 322 PHE C CG  1 
ATOM   8339  C CD1 . PHE C 3 299 ? 174.234 180.077 169.327 1.00 65.86  ? 322 PHE C CD1 1 
ATOM   8340  C CD2 . PHE C 3 299 ? 174.572 181.404 167.379 1.00 65.86  ? 322 PHE C CD2 1 
ATOM   8341  C CE1 . PHE C 3 299 ? 172.869 180.253 169.213 1.00 65.86  ? 322 PHE C CE1 1 
ATOM   8342  C CE2 . PHE C 3 299 ? 173.208 181.585 167.260 1.00 65.86  ? 322 PHE C CE2 1 
ATOM   8343  C CZ  . PHE C 3 299 ? 172.356 181.008 168.178 1.00 65.86  ? 322 PHE C CZ  1 
ATOM   8344  N N   . ASN C 3 300 ? 177.184 183.281 167.956 1.00 77.68  ? 323 ASN C N   1 
ATOM   8345  C CA  . ASN C 3 300 ? 176.883 184.616 167.469 1.00 77.68  ? 323 ASN C CA  1 
ATOM   8346  C C   . ASN C 3 300 ? 175.943 184.525 166.275 1.00 77.68  ? 323 ASN C C   1 
ATOM   8347  O O   . ASN C 3 300 ? 175.927 183.524 165.553 1.00 77.68  ? 323 ASN C O   1 
ATOM   8348  C CB  . ASN C 3 300 ? 178.160 185.361 167.071 1.00 77.68  ? 323 ASN C CB  1 
ATOM   8349  C CG  . ASN C 3 300 ? 178.179 186.790 167.566 1.00 77.68  ? 323 ASN C CG  1 
ATOM   8350  O OD1 . ASN C 3 300 ? 177.138 187.440 167.663 1.00 77.68  ? 323 ASN C OD1 1 
ATOM   8351  N ND2 . ASN C 3 300 ? 179.368 187.288 167.881 1.00 77.68  ? 323 ASN C ND2 1 
ATOM   8352  N N   . LEU C 3 301 ? 175.159 185.585 166.067 1.00 76.85  ? 324 LEU C N   1 
ATOM   8353  C CA  . LEU C 3 301 ? 174.200 185.578 164.967 1.00 76.85  ? 324 LEU C CA  1 
ATOM   8354  C C   . LEU C 3 301 ? 174.892 185.783 163.625 1.00 76.85  ? 324 LEU C C   1 
ATOM   8355  O O   . LEU C 3 301 ? 174.569 185.102 162.645 1.00 76.85  ? 324 LEU C O   1 
ATOM   8356  C CB  . LEU C 3 301 ? 173.134 186.649 165.189 1.00 76.85  ? 324 LEU C CB  1 
ATOM   8357  C CG  . LEU C 3 301 ? 172.006 186.677 164.156 1.00 76.85  ? 324 LEU C CG  1 
ATOM   8358  C CD1 . LEU C 3 301 ? 171.395 185.294 163.989 1.00 76.85  ? 324 LEU C CD1 1 
ATOM   8359  C CD2 . LEU C 3 301 ? 170.943 187.692 164.548 1.00 76.85  ? 324 LEU C CD2 1 
ATOM   8360  N N   . THR C 3 302 ? 175.843 186.713 163.560 1.00 76.89  ? 325 THR C N   1 
ATOM   8361  C CA  . THR C 3 302 ? 176.533 187.010 162.311 1.00 76.89  ? 325 THR C CA  1 
ATOM   8362  C C   . THR C 3 302 ? 177.593 185.977 161.951 1.00 76.89  ? 325 THR C C   1 
ATOM   8363  O O   . THR C 3 302 ? 178.049 185.961 160.803 1.00 76.89  ? 325 THR C O   1 
ATOM   8364  C CB  . THR C 3 302 ? 177.182 188.395 162.381 1.00 76.89  ? 325 THR C CB  1 
ATOM   8365  O OG1 . THR C 3 302 ? 178.074 188.451 163.501 1.00 76.89  ? 325 THR C OG1 1 
ATOM   8366  C CG2 . THR C 3 302 ? 176.121 189.473 162.532 1.00 76.89  ? 325 THR C CG2 1 
ATOM   8367  N N   . HIS C 3 303 ? 177.993 185.121 162.889 1.00 68.38  ? 326 HIS C N   1 
ATOM   8368  C CA  . HIS C 3 303 ? 179.045 184.144 162.653 1.00 68.38  ? 326 HIS C CA  1 
ATOM   8369  C C   . HIS C 3 303 ? 178.515 182.778 162.241 1.00 68.38  ? 326 HIS C C   1 
ATOM   8370  O O   . HIS C 3 303 ? 179.311 181.858 162.034 1.00 68.38  ? 326 HIS C O   1 
ATOM   8371  C CB  . HIS C 3 303 ? 179.919 183.996 163.903 1.00 68.38  ? 326 HIS C CB  1 
ATOM   8372  C CG  . HIS C 3 303 ? 180.739 185.209 164.213 1.00 68.38  ? 326 HIS C CG  1 
ATOM   8373  N ND1 . HIS C 3 303 ? 181.728 185.212 165.173 1.00 68.38  ? 326 HIS C ND1 1 
ATOM   8374  C CD2 . HIS C 3 303 ? 180.717 186.458 163.692 1.00 68.38  ? 326 HIS C CD2 1 
ATOM   8375  C CE1 . HIS C 3 303 ? 182.281 186.410 165.229 1.00 68.38  ? 326 HIS C CE1 1 
ATOM   8376  N NE2 . HIS C 3 303 ? 181.685 187.185 164.341 1.00 68.38  ? 326 HIS C NE2 1 
ATOM   8377  N N   . ARG C 3 304 ? 177.200 182.620 162.119 1.00 69.63  ? 327 ARG C N   1 
ATOM   8378  C CA  . ARG C 3 304 ? 176.587 181.352 161.736 1.00 69.63  ? 327 ARG C CA  1 
ATOM   8379  C C   . ARG C 3 304 ? 175.511 181.578 160.683 1.00 69.63  ? 327 ARG C C   1 
ATOM   8380  O O   . ARG C 3 304 ? 174.405 181.041 160.760 1.00 69.63  ? 327 ARG C O   1 
ATOM   8381  C CB  . ARG C 3 304 ? 176.011 180.636 162.953 1.00 69.63  ? 327 ARG C CB  1 
ATOM   8382  C CG  . ARG C 3 304 ? 177.057 179.974 163.832 1.00 69.63  ? 327 ARG C CG  1 
ATOM   8383  C CD  . ARG C 3 304 ? 176.422 179.345 165.057 1.00 69.63  ? 327 ARG C CD  1 
ATOM   8384  N NE  . ARG C 3 304 ? 177.396 178.615 165.863 1.00 69.63  ? 327 ARG C NE  1 
ATOM   8385  C CZ  . ARG C 3 304 ? 177.527 177.293 165.858 1.00 69.63  ? 327 ARG C CZ  1 
ATOM   8386  N NH1 . ARG C 3 304 ? 176.745 176.551 165.087 1.00 69.63  ? 327 ARG C NH1 1 
ATOM   8387  N NH2 . ARG C 3 304 ? 178.440 176.713 166.625 1.00 69.63  ? 327 ARG C NH2 1 
ATOM   8388  N N   . VAL C 3 305 ? 175.832 182.381 159.674 1.00 75.78  ? 328 VAL C N   1 
ATOM   8389  C CA  . VAL C 3 305 ? 174.885 182.720 158.619 1.00 75.78  ? 328 VAL C CA  1 
ATOM   8390  C C   . VAL C 3 305 ? 175.077 181.765 157.450 1.00 75.78  ? 328 VAL C C   1 
ATOM   8391  O O   . VAL C 3 305 ? 176.196 181.587 156.956 1.00 75.78  ? 328 VAL C O   1 
ATOM   8392  C CB  . VAL C 3 305 ? 175.061 184.180 158.171 1.00 75.78  ? 328 VAL C CB  1 
ATOM   8393  C CG1 . VAL C 3 305 ? 173.917 184.592 157.259 1.00 75.78  ? 328 VAL C CG1 1 
ATOM   8394  C CG2 . VAL C 3 305 ? 175.146 185.098 159.378 1.00 75.78  ? 328 VAL C CG2 1 
ATOM   8395  N N   . HIS C 3 306 ? 173.980 181.150 157.005 1.00 72.84  ? 329 HIS C N   1 
ATOM   8396  C CA  . HIS C 3 306 ? 173.974 180.234 155.865 1.00 72.84  ? 329 HIS C CA  1 
ATOM   8397  C C   . HIS C 3 306 ? 173.133 180.861 154.762 1.00 72.84  ? 329 HIS C C   1 
ATOM   8398  O O   . HIS C 3 306 ? 171.903 180.695 154.737 1.00 72.84  ? 329 HIS C O   1 
ATOM   8399  C CB  . HIS C 3 306 ? 173.434 178.863 156.263 1.00 72.84  ? 329 HIS C CB  1 
ATOM   8400  C CG  . HIS C 3 306 ? 173.187 177.949 155.103 1.00 72.84  ? 329 HIS C CG  1 
ATOM   8401  N ND1 . HIS C 3 306 ? 171.991 177.922 154.420 1.00 72.84  ? 329 HIS C ND1 1 
ATOM   8402  C CD2 . HIS C 3 306 ? 173.981 177.028 154.509 1.00 72.84  ? 329 HIS C CD2 1 
ATOM   8403  C CE1 . HIS C 3 306 ? 172.059 177.024 153.453 1.00 72.84  ? 329 HIS C CE1 1 
ATOM   8404  N NE2 . HIS C 3 306 ? 173.256 176.468 153.485 1.00 72.84  ? 329 HIS C NE2 1 
ATOM   8405  N N   . PRO C 3 307 ? 173.747 181.596 153.836 1.00 87.05  ? 330 PRO C N   1 
ATOM   8406  C CA  . PRO C 3 307 ? 172.968 182.255 152.782 1.00 87.05  ? 330 PRO C CA  1 
ATOM   8407  C C   . PRO C 3 307 ? 172.293 181.244 151.867 1.00 87.05  ? 330 PRO C C   1 
ATOM   8408  O O   . PRO C 3 307 ? 172.820 180.163 151.598 1.00 87.05  ? 330 PRO C O   1 
ATOM   8409  C CB  . PRO C 3 307 ? 174.016 183.080 152.025 1.00 87.05  ? 330 PRO C CB  1 
ATOM   8410  C CG  . PRO C 3 307 ? 175.172 183.204 152.969 1.00 87.05  ? 330 PRO C CG  1 
ATOM   8411  C CD  . PRO C 3 307 ? 175.176 181.938 153.765 1.00 87.05  ? 330 PRO C CD  1 
ATOM   8412  N N   . LYS C 3 308 ? 171.105 181.611 151.394 1.00 102.78 ? 331 LYS C N   1 
ATOM   8413  C CA  . LYS C 3 308 ? 170.337 180.768 150.493 1.00 102.78 ? 331 LYS C CA  1 
ATOM   8414  C C   . LYS C 3 308 ? 170.711 181.073 149.044 1.00 102.78 ? 331 LYS C C   1 
ATOM   8415  O O   . LYS C 3 308 ? 171.601 181.877 148.757 1.00 102.78 ? 331 LYS C O   1 
ATOM   8416  C CB  . LYS C 3 308 ? 168.841 180.963 150.732 1.00 102.78 ? 331 LYS C CB  1 
ATOM   8417  C CG  . LYS C 3 308 ? 168.403 182.417 150.747 1.00 102.78 ? 331 LYS C CG  1 
ATOM   8418  C CD  . LYS C 3 308 ? 166.968 182.559 151.224 1.00 102.78 ? 331 LYS C CD  1 
ATOM   8419  C CE  . LYS C 3 308 ? 166.577 184.020 151.365 1.00 102.78 ? 331 LYS C CE  1 
ATOM   8420  N NZ  . LYS C 3 308 ? 165.191 184.177 151.886 1.00 102.78 ? 331 LYS C NZ  1 
ATOM   8421  N N   . ALA C 3 309 ? 170.020 180.419 148.115 1.00 122.82 ? 332 ALA C N   1 
ATOM   8422  C CA  . ALA C 3 309 ? 170.291 180.635 146.703 1.00 122.82 ? 332 ALA C CA  1 
ATOM   8423  C C   . ALA C 3 309 ? 169.849 182.038 146.291 1.00 122.82 ? 332 ALA C C   1 
ATOM   8424  O O   . ALA C 3 309 ? 168.809 182.522 146.748 1.00 122.82 ? 332 ALA C O   1 
ATOM   8425  C CB  . ALA C 3 309 ? 169.575 179.589 145.850 1.00 122.82 ? 332 ALA C CB  1 
ATOM   8426  N N   . PRO C 3 310 ? 170.616 182.716 145.440 1.00 132.97 ? 333 PRO C N   1 
ATOM   8427  C CA  . PRO C 3 310 ? 170.231 184.064 145.012 1.00 132.97 ? 333 PRO C CA  1 
ATOM   8428  C C   . PRO C 3 310 ? 168.953 184.047 144.188 1.00 132.97 ? 333 PRO C C   1 
ATOM   8429  O O   . PRO C 3 310 ? 168.569 183.037 143.595 1.00 132.97 ? 333 PRO C O   1 
ATOM   8430  C CB  . PRO C 3 310 ? 171.426 184.529 144.170 1.00 132.97 ? 333 PRO C CB  1 
ATOM   8431  C CG  . PRO C 3 310 ? 172.556 183.625 144.562 1.00 132.97 ? 333 PRO C CG  1 
ATOM   8432  C CD  . PRO C 3 310 ? 171.921 182.313 144.893 1.00 132.97 ? 333 PRO C CD  1 
ATOM   8433  N N   . GLN C 3 311 ? 168.290 185.200 144.161 1.00 155.25 ? 334 GLN C N   1 
ATOM   8434  C CA  . GLN C 3 311 ? 167.044 185.382 143.431 1.00 155.25 ? 334 GLN C CA  1 
ATOM   8435  C C   . GLN C 3 311 ? 167.194 186.554 142.468 1.00 155.25 ? 334 GLN C C   1 
ATOM   8436  O O   . GLN C 3 311 ? 168.230 187.226 142.430 1.00 155.25 ? 334 GLN C O   1 
ATOM   8437  C CB  . GLN C 3 311 ? 165.868 185.607 144.389 1.00 155.25 ? 334 GLN C CB  1 
ATOM   8438  C CG  . GLN C 3 311 ? 165.647 184.473 145.376 1.00 155.25 ? 334 GLN C CG  1 
ATOM   8439  C CD  . GLN C 3 311 ? 164.482 184.733 146.309 1.00 155.25 ? 334 GLN C CD  1 
ATOM   8440  O OE1 . GLN C 3 311 ? 163.806 185.757 146.206 1.00 155.25 ? 334 GLN C OE1 1 
ATOM   8441  N NE2 . GLN C 3 311 ? 164.240 183.806 147.228 1.00 155.25 ? 334 GLN C NE2 1 
ATOM   8442  N N   . ASP C 3 312 ? 166.142 186.791 141.681 1.00 162.23 ? 335 ASP C N   1 
ATOM   8443  C CA  . ASP C 3 312 ? 166.108 187.882 140.705 1.00 162.23 ? 335 ASP C CA  1 
ATOM   8444  C C   . ASP C 3 312 ? 167.273 187.787 139.723 1.00 162.23 ? 335 ASP C C   1 
ATOM   8445  O O   . ASP C 3 312 ? 167.853 188.795 139.317 1.00 162.23 ? 335 ASP C O   1 
ATOM   8446  C CB  . ASP C 3 312 ? 166.091 189.246 141.401 1.00 162.23 ? 335 ASP C CB  1 
ATOM   8447  C CG  . ASP C 3 312 ? 165.085 189.310 142.534 1.00 162.23 ? 335 ASP C CG  1 
ATOM   8448  O OD1 . ASP C 3 312 ? 163.889 189.539 142.257 1.00 162.23 ? 335 ASP C OD1 1 
ATOM   8449  O OD2 . ASP C 3 312 ? 165.491 189.131 143.701 1.00 162.23 ? 335 ASP C OD2 1 
ATOM   8450  N N   . VAL C 3 313 ? 167.621 186.562 139.341 1.00 167.94 ? 336 VAL C N   1 
ATOM   8451  C CA  . VAL C 3 313 ? 168.732 186.330 138.425 1.00 167.94 ? 336 VAL C CA  1 
ATOM   8452  C C   . VAL C 3 313 ? 168.273 186.617 136.999 1.00 167.94 ? 336 VAL C C   1 
ATOM   8453  O O   . VAL C 3 313 ? 167.336 185.990 136.494 1.00 167.94 ? 336 VAL C O   1 
ATOM   8454  C CB  . VAL C 3 313 ? 169.279 184.901 138.568 1.00 167.94 ? 336 VAL C CB  1 
ATOM   8455  C CG1 . VAL C 3 313 ? 168.156 183.871 138.498 1.00 167.94 ? 336 VAL C CG1 1 
ATOM   8456  C CG2 . VAL C 3 313 ? 170.325 184.626 137.501 1.00 167.94 ? 336 VAL C CG2 1 
ATOM   8457  N N   . THR C 3 314 ? 168.925 187.582 136.353 1.00 176.36 ? 337 THR C N   1 
ATOM   8458  C CA  . THR C 3 314 ? 168.605 187.969 134.986 1.00 176.36 ? 337 THR C CA  1 
ATOM   8459  C C   . THR C 3 314 ? 169.891 188.310 134.250 1.00 176.36 ? 337 THR C C   1 
ATOM   8460  O O   . THR C 3 314 ? 170.795 188.928 134.819 1.00 176.36 ? 337 THR C O   1 
ATOM   8461  C CB  . THR C 3 314 ? 167.650 189.172 134.941 1.00 176.36 ? 337 THR C CB  1 
ATOM   8462  O OG1 . THR C 3 314 ? 168.064 190.151 135.902 1.00 176.36 ? 337 THR C OG1 1 
ATOM   8463  C CG2 . THR C 3 314 ? 166.219 188.742 135.237 1.00 176.36 ? 337 THR C CG2 1 
ATOM   8464  N N   . LEU C 3 315 ? 169.964 187.913 132.982 1.00 181.23 ? 338 LEU C N   1 
ATOM   8465  C CA  . LEU C 3 315 ? 171.134 188.153 132.152 1.00 181.23 ? 338 LEU C CA  1 
ATOM   8466  C C   . LEU C 3 315 ? 170.731 188.941 130.916 1.00 181.23 ? 338 LEU C C   1 
ATOM   8467  O O   . LEU C 3 315 ? 169.649 188.731 130.358 1.00 181.23 ? 338 LEU C O   1 
ATOM   8468  C CB  . LEU C 3 315 ? 171.805 186.835 131.740 1.00 181.23 ? 338 LEU C CB  1 
ATOM   8469  C CG  . LEU C 3 315 ? 173.186 186.936 131.087 1.00 181.23 ? 338 LEU C CG  1 
ATOM   8470  C CD1 . LEU C 3 315 ? 174.123 185.879 131.648 1.00 181.23 ? 338 LEU C CD1 1 
ATOM   8471  C CD2 . LEU C 3 315 ? 173.081 186.810 129.574 1.00 181.23 ? 338 LEU C CD2 1 
ATOM   8472  N N   . LYS C 3 316 ? 171.607 189.850 130.492 1.00 178.59 ? 339 LYS C N   1 
ATOM   8473  C CA  . LYS C 3 316 ? 171.386 190.663 129.307 1.00 178.59 ? 339 LYS C CA  1 
ATOM   8474  C C   . LYS C 3 316 ? 172.641 190.657 128.446 1.00 178.59 ? 339 LYS C C   1 
ATOM   8475  O O   . LYS C 3 316 ? 173.763 190.581 128.956 1.00 178.59 ? 339 LYS C O   1 
ATOM   8476  C CB  . LYS C 3 316 ? 171.007 192.105 129.673 1.00 178.59 ? 339 LYS C CB  1 
ATOM   8477  C CG  . LYS C 3 316 ? 171.996 192.791 130.601 1.00 178.59 ? 339 LYS C CG  1 
ATOM   8478  C CD  . LYS C 3 316 ? 171.541 194.199 130.949 1.00 178.59 ? 339 LYS C CD  1 
ATOM   8479  C CE  . LYS C 3 316 ? 170.176 194.190 131.616 1.00 178.59 ? 339 LYS C CE  1 
ATOM   8480  N NZ  . LYS C 3 316 ? 170.174 193.377 132.864 1.00 178.59 ? 339 LYS C NZ  1 
ATOM   8481  N N   . ILE C 3 317 ? 172.440 190.737 127.135 1.00 183.41 ? 340 ILE C N   1 
ATOM   8482  C CA  . ILE C 3 317 ? 173.531 190.727 126.167 1.00 183.41 ? 340 ILE C CA  1 
ATOM   8483  C C   . ILE C 3 317 ? 173.716 192.142 125.640 1.00 183.41 ? 340 ILE C C   1 
ATOM   8484  O O   . ILE C 3 317 ? 172.781 192.738 125.091 1.00 183.41 ? 340 ILE C O   1 
ATOM   8485  C CB  . ILE C 3 317 ? 173.255 189.741 125.021 1.00 183.41 ? 340 ILE C CB  1 
ATOM   8486  C CG1 . ILE C 3 317 ? 173.246 188.304 125.546 1.00 183.41 ? 340 ILE C CG1 1 
ATOM   8487  C CG2 . ILE C 3 317 ? 174.288 189.904 123.918 1.00 183.41 ? 340 ILE C CG2 1 
ATOM   8488  C CD1 . ILE C 3 317 ? 173.023 187.263 124.471 1.00 183.41 ? 340 ILE C CD1 1 
ATOM   8489  N N   . ILE C 3 318 ? 174.922 192.683 125.806 1.00 185.46 ? 341 ILE C N   1 
ATOM   8490  C CA  . ILE C 3 318 ? 175.243 194.024 125.330 1.00 185.46 ? 341 ILE C CA  1 
ATOM   8491  C C   . ILE C 3 318 ? 176.321 193.906 124.259 1.00 185.46 ? 341 ILE C C   1 
ATOM   8492  O O   . ILE C 3 318 ? 177.154 194.804 124.091 1.00 185.46 ? 341 ILE C O   1 
ATOM   8493  C CB  . ILE C 3 318 ? 175.694 194.939 126.485 1.00 185.46 ? 341 ILE C CB  1 
ATOM   8494  C CG1 . ILE C 3 318 ? 174.921 194.613 127.765 1.00 185.46 ? 341 ILE C CG1 1 
ATOM   8495  C CG2 . ILE C 3 318 ? 175.475 196.404 126.128 1.00 185.46 ? 341 ILE C CG2 1 
ATOM   8496  C CD1 . ILE C 3 318 ? 173.443 194.945 127.694 1.00 185.46 ? 341 ILE C CD1 1 
ATOM   8497  N N   . GLY C 3 319 ? 176.314 192.792 123.532 1.00 190.30 ? 342 GLY C N   1 
ATOM   8498  C CA  . GLY C 3 319 ? 177.291 192.566 122.485 1.00 190.30 ? 342 GLY C CA  1 
ATOM   8499  C C   . GLY C 3 319 ? 177.764 191.129 122.418 1.00 190.30 ? 342 GLY C C   1 
ATOM   8500  O O   . GLY C 3 319 ? 177.499 190.337 123.327 1.00 190.30 ? 342 GLY C O   1 
ATOM   8501  N N   . ALA C 3 320 ? 178.470 190.779 121.341 1.00 194.96 ? 343 ALA C N   1 
ATOM   8502  C CA  . ALA C 3 320 ? 178.959 189.417 121.172 1.00 194.96 ? 343 ALA C CA  1 
ATOM   8503  C C   . ALA C 3 320 ? 180.127 189.088 122.091 1.00 194.96 ? 343 ALA C C   1 
ATOM   8504  O O   . ALA C 3 320 ? 180.439 187.904 122.265 1.00 194.96 ? 343 ALA C O   1 
ATOM   8505  C CB  . ALA C 3 320 ? 179.368 189.182 119.717 1.00 194.96 ? 343 ALA C CB  1 
ATOM   8506  N N   . THR C 3 321 ? 180.777 190.093 122.679 1.00 192.37 ? 344 THR C N   1 
ATOM   8507  C CA  . THR C 3 321 ? 181.910 189.873 123.566 1.00 192.37 ? 344 THR C CA  1 
ATOM   8508  C C   . THR C 3 321 ? 181.688 190.413 124.972 1.00 192.37 ? 344 THR C C   1 
ATOM   8509  O O   . THR C 3 321 ? 182.575 190.265 125.820 1.00 192.37 ? 344 THR C O   1 
ATOM   8510  C CB  . THR C 3 321 ? 183.182 190.506 122.981 1.00 192.37 ? 344 THR C CB  1 
ATOM   8511  O OG1 . THR C 3 321 ? 183.165 191.920 123.213 1.00 192.37 ? 344 THR C OG1 1 
ATOM   8512  C CG2 . THR C 3 321 ? 183.279 190.241 121.485 1.00 192.37 ? 344 THR C CG2 1 
ATOM   8513  N N   . LYS C 3 322 ? 180.541 191.030 125.246 1.00 186.71 ? 345 LYS C N   1 
ATOM   8514  C CA  . LYS C 3 322 ? 180.257 191.616 126.548 1.00 186.71 ? 345 LYS C CA  1 
ATOM   8515  C C   . LYS C 3 322 ? 178.854 191.229 126.991 1.00 186.71 ? 345 LYS C C   1 
ATOM   8516  O O   . LYS C 3 322 ? 177.944 191.109 126.165 1.00 186.71 ? 345 LYS C O   1 
ATOM   8517  C CB  . LYS C 3 322 ? 180.394 193.144 126.513 1.00 186.71 ? 345 LYS C CB  1 
ATOM   8518  C CG  . LYS C 3 322 ? 181.783 193.634 126.133 1.00 186.71 ? 345 LYS C CG  1 
ATOM   8519  C CD  . LYS C 3 322 ? 181.834 195.150 126.044 1.00 186.71 ? 345 LYS C CD  1 
ATOM   8520  C CE  . LYS C 3 322 ? 183.210 195.628 125.607 1.00 186.71 ? 345 LYS C CE  1 
ATOM   8521  N NZ  . LYS C 3 322 ? 183.276 197.112 125.501 1.00 186.71 ? 345 LYS C NZ  1 
ATOM   8522  N N   . ALA C 3 323 ? 178.686 191.039 128.298 1.00 172.39 ? 346 ALA C N   1 
ATOM   8523  C CA  . ALA C 3 323 ? 177.399 190.654 128.860 1.00 172.39 ? 346 ALA C CA  1 
ATOM   8524  C C   . ALA C 3 323 ? 177.387 190.985 130.345 1.00 172.39 ? 346 ALA C C   1 
ATOM   8525  O O   . ALA C 3 323 ? 178.424 190.915 131.010 1.00 172.39 ? 346 ALA C O   1 
ATOM   8526  C CB  . ALA C 3 323 ? 177.118 189.162 128.646 1.00 172.39 ? 346 ALA C CB  1 
ATOM   8527  N N   . ASN C 3 324 ? 176.213 191.343 130.854 1.00 172.30 ? 347 ASN C N   1 
ATOM   8528  C CA  . ASN C 3 324 ? 176.028 191.676 132.257 1.00 172.30 ? 347 ASN C CA  1 
ATOM   8529  C C   . ASN C 3 324 ? 175.350 190.521 132.987 1.00 172.30 ? 347 ASN C C   1 
ATOM   8530  O O   . ASN C 3 324 ? 174.622 189.723 132.391 1.00 172.30 ? 347 ASN C O   1 
ATOM   8531  C CB  . ASN C 3 324 ? 175.200 192.958 132.408 1.00 172.30 ? 347 ASN C CB  1 
ATOM   8532  C CG  . ASN C 3 324 ? 175.152 193.467 133.844 1.00 172.30 ? 347 ASN C CG  1 
ATOM   8533  O OD1 . ASN C 3 324 ? 174.830 192.718 134.765 1.00 172.30 ? 347 ASN C OD1 1 
ATOM   8534  N ND2 . ASN C 3 324 ? 175.468 194.745 134.041 1.00 172.30 ? 347 ASN C ND2 1 
ATOM   8535  N N   . MET C 3 325 ? 175.602 190.442 134.293 1.00 173.49 ? 348 MET C N   1 
ATOM   8536  C CA  . MET C 3 325 ? 175.032 189.414 135.159 1.00 173.49 ? 348 MET C CA  1 
ATOM   8537  C C   . MET C 3 325 ? 174.370 190.108 136.342 1.00 173.49 ? 348 MET C C   1 
ATOM   8538  O O   . MET C 3 325 ? 175.060 190.631 137.223 1.00 173.49 ? 348 MET C O   1 
ATOM   8539  C CB  . MET C 3 325 ? 176.108 188.434 135.630 1.00 173.49 ? 348 MET C CB  1 
ATOM   8540  C CG  . MET C 3 325 ? 175.593 187.166 136.307 1.00 173.49 ? 348 MET C CG  1 
ATOM   8541  S SD  . MET C 3 325 ? 174.462 186.179 135.304 1.00 173.49 ? 348 MET C SD  1 
ATOM   8542  C CE  . MET C 3 325 ? 172.871 186.730 135.914 1.00 173.49 ? 348 MET C CE  1 
ATOM   8543  N N   . THR C 3 326 ? 173.040 190.117 136.364 1.00 169.75 ? 349 THR C N   1 
ATOM   8544  C CA  . THR C 3 326 ? 172.271 190.806 137.392 1.00 169.75 ? 349 THR C CA  1 
ATOM   8545  C C   . THR C 3 326 ? 171.645 189.793 138.340 1.00 169.75 ? 349 THR C C   1 
ATOM   8546  O O   . THR C 3 326 ? 171.065 188.797 137.896 1.00 169.75 ? 349 THR C O   1 
ATOM   8547  C CB  . THR C 3 326 ? 171.180 191.681 136.770 1.00 169.75 ? 349 THR C CB  1 
ATOM   8548  O OG1 . THR C 3 326 ? 170.299 190.865 135.989 1.00 169.75 ? 349 THR C OG1 1 
ATOM   8549  C CG2 . THR C 3 326 ? 171.793 192.750 135.880 1.00 169.75 ? 349 THR C CG2 1 
ATOM   8550  N N   . TRP C 3 327 ? 171.762 190.052 139.641 1.00 156.08 ? 350 TRP C N   1 
ATOM   8551  C CA  . TRP C 3 327 ? 171.143 189.204 140.651 1.00 156.08 ? 350 TRP C CA  1 
ATOM   8552  C C   . TRP C 3 327 ? 170.925 190.025 141.914 1.00 156.08 ? 350 TRP C C   1 
ATOM   8553  O O   . TRP C 3 327 ? 171.520 191.090 142.094 1.00 156.08 ? 350 TRP C O   1 
ATOM   8554  C CB  . TRP C 3 327 ? 171.993 187.963 140.946 1.00 156.08 ? 350 TRP C CB  1 
ATOM   8555  C CG  . TRP C 3 327 ? 173.227 188.242 141.749 1.00 156.08 ? 350 TRP C CG  1 
ATOM   8556  C CD1 . TRP C 3 327 ? 173.358 188.157 143.105 1.00 156.08 ? 350 TRP C CD1 1 
ATOM   8557  C CD2 . TRP C 3 327 ? 174.507 188.641 141.247 1.00 156.08 ? 350 TRP C CD2 1 
ATOM   8558  N NE1 . TRP C 3 327 ? 174.640 188.483 143.478 1.00 156.08 ? 350 TRP C NE1 1 
ATOM   8559  C CE2 . TRP C 3 327 ? 175.365 188.784 142.355 1.00 156.08 ? 350 TRP C CE2 1 
ATOM   8560  C CE3 . TRP C 3 327 ? 175.011 188.893 139.967 1.00 156.08 ? 350 TRP C CE3 1 
ATOM   8561  C CZ2 . TRP C 3 327 ? 176.698 189.167 142.223 1.00 156.08 ? 350 TRP C CZ2 1 
ATOM   8562  C CZ3 . TRP C 3 327 ? 176.335 189.274 139.839 1.00 156.08 ? 350 TRP C CZ3 1 
ATOM   8563  C CH2 . TRP C 3 327 ? 177.163 189.407 140.960 1.00 156.08 ? 350 TRP C CH2 1 
ATOM   8564  N N   . LYS C 3 328 ? 170.062 189.509 142.788 1.00 154.82 ? 351 LYS C N   1 
ATOM   8565  C CA  . LYS C 3 328 ? 169.705 190.191 144.025 1.00 154.82 ? 351 LYS C CA  1 
ATOM   8566  C C   . LYS C 3 328 ? 169.616 189.179 145.157 1.00 154.82 ? 351 LYS C C   1 
ATOM   8567  O O   . LYS C 3 328 ? 169.165 188.048 144.955 1.00 154.82 ? 351 LYS C O   1 
ATOM   8568  C CB  . LYS C 3 328 ? 168.373 190.937 143.884 1.00 154.82 ? 351 LYS C CB  1 
ATOM   8569  C CG  . LYS C 3 328 ? 168.110 191.958 144.977 1.00 154.82 ? 351 LYS C CG  1 
ATOM   8570  C CD  . LYS C 3 328 ? 166.892 192.804 144.648 1.00 154.82 ? 351 LYS C CD  1 
ATOM   8571  C CE  . LYS C 3 328 ? 166.683 193.905 145.674 1.00 154.82 ? 351 LYS C CE  1 
ATOM   8572  N NZ  . LYS C 3 328 ? 165.529 194.775 145.316 1.00 154.82 ? 351 LYS C NZ  1 
ATOM   8573  N N   . VAL C 3 329 ? 170.047 189.591 146.347 1.00 153.06 ? 352 VAL C N   1 
ATOM   8574  C CA  . VAL C 3 329 ? 170.049 188.734 147.523 1.00 153.06 ? 352 VAL C CA  1 
ATOM   8575  C C   . VAL C 3 329 ? 169.294 189.448 148.644 1.00 153.06 ? 352 VAL C C   1 
ATOM   8576  O O   . VAL C 3 329 ? 168.895 190.606 148.515 1.00 153.06 ? 352 VAL C O   1 
ATOM   8577  C CB  . VAL C 3 329 ? 171.481 188.359 147.960 1.00 153.06 ? 352 VAL C CB  1 
ATOM   8578  C CG1 . VAL C 3 329 ? 172.161 189.539 148.646 1.00 153.06 ? 352 VAL C CG1 1 
ATOM   8579  C CG2 . VAL C 3 329 ? 171.490 187.093 148.820 1.00 153.06 ? 352 VAL C CG2 1 
ATOM   8580  N N   . HIS C 3 330 ? 169.102 188.737 149.754 1.00 146.97 ? 353 HIS C N   1 
ATOM   8581  C CA  . HIS C 3 330 ? 168.377 189.240 150.916 1.00 146.97 ? 353 HIS C CA  1 
ATOM   8582  C C   . HIS C 3 330 ? 169.389 189.564 152.008 1.00 146.97 ? 353 HIS C C   1 
ATOM   8583  O O   . HIS C 3 330 ? 170.085 188.670 152.502 1.00 146.97 ? 353 HIS C O   1 
ATOM   8584  C CB  . HIS C 3 330 ? 167.357 188.214 151.406 1.00 146.97 ? 353 HIS C CB  1 
ATOM   8585  C CG  . HIS C 3 330 ? 166.315 187.865 150.390 1.00 146.97 ? 353 HIS C CG  1 
ATOM   8586  N ND1 . HIS C 3 330 ? 166.618 187.251 149.193 1.00 146.97 ? 353 HIS C ND1 1 
ATOM   8587  C CD2 . HIS C 3 330 ? 164.973 188.041 150.392 1.00 146.97 ? 353 HIS C CD2 1 
ATOM   8588  C CE1 . HIS C 3 330 ? 165.508 187.065 148.502 1.00 146.97 ? 353 HIS C CE1 1 
ATOM   8589  N NE2 . HIS C 3 330 ? 164.495 187.536 149.207 1.00 146.97 ? 353 HIS C NE2 1 
ATOM   8590  N N   . SER C 3 331 ? 169.470 190.838 152.385 1.00 149.75 ? 354 SER C N   1 
ATOM   8591  C CA  . SER C 3 331 ? 170.414 191.299 153.392 1.00 149.75 ? 354 SER C CA  1 
ATOM   8592  C C   . SER C 3 331 ? 169.684 192.108 154.453 1.00 149.75 ? 354 SER C C   1 
ATOM   8593  O O   . SER C 3 331 ? 168.760 192.866 154.143 1.00 149.75 ? 354 SER C O   1 
ATOM   8594  C CB  . SER C 3 331 ? 171.529 192.147 152.766 1.00 149.75 ? 354 SER C CB  1 
ATOM   8595  O OG  . SER C 3 331 ? 172.127 192.996 153.731 1.00 149.75 ? 354 SER C OG  1 
ATOM   8596  N N   . HIS C 3 332 ? 170.105 191.941 155.704 1.00 143.20 ? 355 HIS C N   1 
ATOM   8597  C CA  . HIS C 3 332 ? 169.540 192.652 156.849 1.00 143.20 ? 355 HIS C CA  1 
ATOM   8598  C C   . HIS C 3 332 ? 170.661 193.470 157.485 1.00 143.20 ? 355 HIS C C   1 
ATOM   8599  O O   . HIS C 3 332 ? 171.413 192.969 158.324 1.00 143.20 ? 355 HIS C O   1 
ATOM   8600  C CB  . HIS C 3 332 ? 168.913 191.680 157.850 1.00 143.20 ? 355 HIS C CB  1 
ATOM   8601  C CG  . HIS C 3 332 ? 168.292 192.351 159.036 1.00 143.20 ? 355 HIS C CG  1 
ATOM   8602  N ND1 . HIS C 3 332 ? 167.215 193.205 158.930 1.00 143.20 ? 355 HIS C ND1 1 
ATOM   8603  C CD2 . HIS C 3 332 ? 168.596 192.292 160.354 1.00 143.20 ? 355 HIS C CD2 1 
ATOM   8604  C CE1 . HIS C 3 332 ? 166.883 193.643 160.131 1.00 143.20 ? 355 HIS C CE1 1 
ATOM   8605  N NE2 . HIS C 3 332 ? 167.705 193.105 161.013 1.00 143.20 ? 355 HIS C NE2 1 
ATOM   8606  N N   . GLY C 3 333 ? 170.768 194.723 157.083 1.00 154.64 ? 356 GLY C N   1 
ATOM   8607  C CA  . GLY C 3 333 ? 171.804 195.602 157.582 1.00 154.64 ? 356 GLY C CA  1 
ATOM   8608  C C   . GLY C 3 333 ? 172.810 195.951 156.498 1.00 154.64 ? 356 GLY C C   1 
ATOM   8609  O O   . GLY C 3 333 ? 173.118 195.146 155.609 1.00 154.64 ? 356 GLY C O   1 
ATOM   8610  N N   . ASN C 3 334 ? 173.333 197.176 156.574 1.00 162.20 ? 357 ASN C N   1 
ATOM   8611  C CA  . ASN C 3 334 ? 174.289 197.648 155.580 1.00 162.20 ? 357 ASN C CA  1 
ATOM   8612  C C   . ASN C 3 334 ? 175.696 197.115 155.814 1.00 162.20 ? 357 ASN C C   1 
ATOM   8613  O O   . ASN C 3 334 ? 176.489 197.065 154.867 1.00 162.20 ? 357 ASN C O   1 
ATOM   8614  C CB  . ASN C 3 334 ? 174.317 199.178 155.559 1.00 162.20 ? 357 ASN C CB  1 
ATOM   8615  C CG  . ASN C 3 334 ? 174.416 199.779 156.947 1.00 162.20 ? 357 ASN C CG  1 
ATOM   8616  O OD1 . ASN C 3 334 ? 174.722 199.087 157.918 1.00 162.20 ? 357 ASN C OD1 1 
ATOM   8617  N ND2 . ASN C 3 334 ? 174.158 201.078 157.047 1.00 162.20 ? 357 ASN C ND2 1 
ATOM   8618  N N   . ASN C 3 335 ? 176.025 196.720 157.046 1.00 152.81 ? 358 ASN C N   1 
ATOM   8619  C CA  . ASN C 3 335 ? 177.364 196.213 157.322 1.00 152.81 ? 358 ASN C CA  1 
ATOM   8620  C C   . ASN C 3 335 ? 177.554 194.800 156.785 1.00 152.81 ? 358 ASN C C   1 
ATOM   8621  O O   . ASN C 3 335 ? 178.675 194.420 156.426 1.00 152.81 ? 358 ASN C O   1 
ATOM   8622  C CB  . ASN C 3 335 ? 177.644 196.251 158.824 1.00 152.81 ? 358 ASN C CB  1 
ATOM   8623  C CG  . ASN C 3 335 ? 179.054 195.808 159.165 1.00 152.81 ? 358 ASN C CG  1 
ATOM   8624  O OD1 . ASN C 3 335 ? 179.309 194.624 159.383 1.00 152.81 ? 358 ASN C OD1 1 
ATOM   8625  N ND2 . ASN C 3 335 ? 179.978 196.760 159.213 1.00 152.81 ? 358 ASN C ND2 1 
ATOM   8626  N N   . TYR C 3 336 ? 176.484 194.012 156.722 1.00 122.17 ? 359 TYR C N   1 
ATOM   8627  C CA  . TYR C 3 336 ? 176.566 192.633 156.254 1.00 122.17 ? 359 TYR C CA  1 
ATOM   8628  C C   . TYR C 3 336 ? 176.686 192.625 154.735 1.00 122.17 ? 359 TYR C C   1 
ATOM   8629  O O   . TYR C 3 336 ? 175.707 192.878 154.026 1.00 122.17 ? 359 TYR C O   1 
ATOM   8630  C CB  . TYR C 3 336 ? 175.345 191.843 156.714 1.00 122.17 ? 359 TYR C CB  1 
ATOM   8631  C CG  . TYR C 3 336 ? 175.334 190.407 156.246 1.00 122.17 ? 359 TYR C CG  1 
ATOM   8632  C CD1 . TYR C 3 336 ? 174.506 189.999 155.208 1.00 122.17 ? 359 TYR C CD1 1 
ATOM   8633  C CD2 . TYR C 3 336 ? 176.154 189.459 156.841 1.00 122.17 ? 359 TYR C CD2 1 
ATOM   8634  C CE1 . TYR C 3 336 ? 174.494 188.686 154.779 1.00 122.17 ? 359 TYR C CE1 1 
ATOM   8635  C CE2 . TYR C 3 336 ? 176.150 188.145 156.419 1.00 122.17 ? 359 TYR C CE2 1 
ATOM   8636  C CZ  . TYR C 3 336 ? 175.319 187.764 155.388 1.00 122.17 ? 359 TYR C CZ  1 
ATOM   8637  O OH  . TYR C 3 336 ? 175.313 186.455 154.967 1.00 122.17 ? 359 TYR C OH  1 
ATOM   8638  N N   . THR C 3 337 ? 177.883 192.333 154.234 1.00 121.81 ? 360 THR C N   1 
ATOM   8639  C CA  . THR C 3 337 ? 178.144 192.252 152.805 1.00 121.81 ? 360 THR C CA  1 
ATOM   8640  C C   . THR C 3 337 ? 178.473 190.815 152.426 1.00 121.81 ? 360 THR C C   1 
ATOM   8641  O O   . THR C 3 337 ? 179.187 190.119 153.154 1.00 121.81 ? 360 THR C O   1 
ATOM   8642  C CB  . THR C 3 337 ? 179.297 193.174 152.398 1.00 121.81 ? 360 THR C CB  1 
ATOM   8643  O OG1 . THR C 3 337 ? 180.504 192.746 153.040 1.00 121.81 ? 360 THR C OG1 1 
ATOM   8644  C CG2 . THR C 3 337 ? 178.996 194.608 152.803 1.00 121.81 ? 360 THR C CG2 1 
ATOM   8645  N N   . LEU C 3 338 ? 177.947 190.374 151.288 1.00 106.97 ? 361 LEU C N   1 
ATOM   8646  C CA  . LEU C 3 338 ? 178.130 189.002 150.838 1.00 106.97 ? 361 LEU C CA  1 
ATOM   8647  C C   . LEU C 3 338 ? 179.321 188.895 149.896 1.00 106.97 ? 361 LEU C C   1 
ATOM   8648  O O   . LEU C 3 338 ? 179.554 189.777 149.065 1.00 106.97 ? 361 LEU C O   1 
ATOM   8649  C CB  . LEU C 3 338 ? 176.868 188.492 150.142 1.00 106.97 ? 361 LEU C CB  1 
ATOM   8650  C CG  . LEU C 3 338 ? 175.807 187.890 151.062 1.00 106.97 ? 361 LEU C CG  1 
ATOM   8651  C CD1 . LEU C 3 338 ? 174.680 187.307 150.243 1.00 106.97 ? 361 LEU C CD1 1 
ATOM   8652  C CD2 . LEU C 3 338 ? 176.415 186.830 151.958 1.00 106.97 ? 361 LEU C CD2 1 
ATOM   8653  N N   . LEU C 3 339 ? 180.076 187.808 150.039 1.00 103.08 ? 362 LEU C N   1 
ATOM   8654  C CA  . LEU C 3 339 ? 181.210 187.497 149.171 1.00 103.08 ? 362 LEU C CA  1 
ATOM   8655  C C   . LEU C 3 339 ? 180.773 186.376 148.232 1.00 103.08 ? 362 LEU C C   1 
ATOM   8656  O O   . LEU C 3 339 ? 180.828 185.197 148.591 1.00 103.08 ? 362 LEU C O   1 
ATOM   8657  C CB  . LEU C 3 339 ? 182.436 187.099 149.988 1.00 103.08 ? 362 LEU C CB  1 
ATOM   8658  C CG  . LEU C 3 339 ? 183.692 186.709 149.203 1.00 103.08 ? 362 LEU C CG  1 
ATOM   8659  C CD1 . LEU C 3 339 ? 184.190 187.875 148.364 1.00 103.08 ? 362 LEU C CD1 1 
ATOM   8660  C CD2 . LEU C 3 339 ? 184.789 186.209 150.134 1.00 103.08 ? 362 LEU C CD2 1 
ATOM   8661  N N   . CYS C 3 340 ? 180.339 186.747 147.034 1.00 115.26 ? 363 CYS C N   1 
ATOM   8662  C CA  . CYS C 3 340 ? 179.854 185.792 146.051 1.00 115.26 ? 363 CYS C CA  1 
ATOM   8663  C C   . CYS C 3 340 ? 180.977 185.371 145.112 1.00 115.26 ? 363 CYS C C   1 
ATOM   8664  O O   . CYS C 3 340 ? 182.039 185.996 145.050 1.00 115.26 ? 363 CYS C O   1 
ATOM   8665  C CB  . CYS C 3 340 ? 178.692 186.382 145.248 1.00 115.26 ? 363 CYS C CB  1 
ATOM   8666  S SG  . CYS C 3 340 ? 177.328 187.008 146.255 1.00 115.26 ? 363 CYS C SG  1 
ATOM   8667  N N   . GLN C 3 341 ? 180.727 184.289 144.378 1.00 113.56 ? 364 GLN C N   1 
ATOM   8668  C CA  . GLN C 3 341 ? 181.685 183.747 143.421 1.00 113.56 ? 364 GLN C CA  1 
ATOM   8669  C C   . GLN C 3 341 ? 180.982 183.536 142.090 1.00 113.56 ? 364 GLN C C   1 
ATOM   8670  O O   . GLN C 3 341 ? 180.016 182.770 142.010 1.00 113.56 ? 364 GLN C O   1 
ATOM   8671  C CB  . GLN C 3 341 ? 182.289 182.433 143.923 1.00 113.56 ? 364 GLN C CB  1 
ATOM   8672  C CG  . GLN C 3 341 ? 183.396 182.611 144.948 1.00 113.56 ? 364 GLN C CG  1 
ATOM   8673  C CD  . GLN C 3 341 ? 184.125 181.317 145.249 1.00 113.56 ? 364 GLN C CD  1 
ATOM   8674  O OE1 . GLN C 3 341 ? 183.641 180.231 144.931 1.00 113.56 ? 364 GLN C OE1 1 
ATOM   8675  N NE2 . GLN C 3 341 ? 185.296 181.427 145.864 1.00 113.56 ? 364 GLN C NE2 1 
ATOM   8676  N N   . VAL C 3 342 ? 181.463 184.211 141.055 1.00 120.29 ? 365 VAL C N   1 
ATOM   8677  C CA  . VAL C 3 342 ? 180.927 184.063 139.708 1.00 120.29 ? 365 VAL C CA  1 
ATOM   8678  C C   . VAL C 3 342 ? 181.729 182.997 138.976 1.00 120.29 ? 365 VAL C C   1 
ATOM   8679  O O   . VAL C 3 342 ? 182.955 182.911 139.116 1.00 120.29 ? 365 VAL C O   1 
ATOM   8680  C CB  . VAL C 3 342 ? 180.948 185.410 138.959 1.00 120.29 ? 365 VAL C CB  1 
ATOM   8681  C CG1 . VAL C 3 342 ? 182.372 185.927 138.804 1.00 120.29 ? 365 VAL C CG1 1 
ATOM   8682  C CG2 . VAL C 3 342 ? 180.268 185.279 137.606 1.00 120.29 ? 365 VAL C CG2 1 
ATOM   8683  N N   . LYS C 3 343 ? 181.033 182.161 138.207 1.00 125.30 ? 366 LYS C N   1 
ATOM   8684  C CA  . LYS C 3 343 ? 181.651 181.050 137.491 1.00 125.30 ? 366 LYS C CA  1 
ATOM   8685  C C   . LYS C 3 343 ? 181.138 181.049 136.058 1.00 125.30 ? 366 LYS C C   1 
ATOM   8686  O O   . LYS C 3 343 ? 179.948 180.819 135.822 1.00 125.30 ? 366 LYS C O   1 
ATOM   8687  C CB  . LYS C 3 343 ? 181.350 179.719 138.181 1.00 125.30 ? 366 LYS C CB  1 
ATOM   8688  C CG  . LYS C 3 343 ? 181.897 178.501 137.461 1.00 125.30 ? 366 LYS C CG  1 
ATOM   8689  C CD  . LYS C 3 343 ? 181.535 177.225 138.202 1.00 125.30 ? 366 LYS C CD  1 
ATOM   8690  C CE  . LYS C 3 343 ? 182.091 175.999 137.500 1.00 125.30 ? 366 LYS C CE  1 
ATOM   8691  N NZ  . LYS C 3 343 ? 181.747 174.745 138.225 1.00 125.30 ? 366 LYS C NZ  1 
ATOM   8692  N N   . LEU C 3 344 ? 182.033 181.305 135.108 1.00 140.57 ? 367 LEU C N   1 
ATOM   8693  C CA  . LEU C 3 344 ? 181.709 181.312 133.686 1.00 140.57 ? 367 LEU C CA  1 
ATOM   8694  C C   . LEU C 3 344 ? 182.335 180.075 133.054 1.00 140.57 ? 367 LEU C C   1 
ATOM   8695  O O   . LEU C 3 344 ? 183.564 179.971 132.966 1.00 140.57 ? 367 LEU C O   1 
ATOM   8696  C CB  . LEU C 3 344 ? 182.213 182.589 133.017 1.00 140.57 ? 367 LEU C CB  1 
ATOM   8697  C CG  . LEU C 3 344 ? 181.959 182.712 131.514 1.00 140.57 ? 367 LEU C CG  1 
ATOM   8698  C CD1 . LEU C 3 344 ? 180.467 182.736 131.224 1.00 140.57 ? 367 LEU C CD1 1 
ATOM   8699  C CD2 . LEU C 3 344 ? 182.638 183.952 130.954 1.00 140.57 ? 367 LEU C CD2 1 
ATOM   8700  N N   . GLN C 3 345 ? 181.494 179.143 132.615 1.00 145.24 ? 368 GLN C N   1 
ATOM   8701  C CA  . GLN C 3 345 ? 181.943 177.873 132.064 1.00 145.24 ? 368 GLN C CA  1 
ATOM   8702  C C   . GLN C 3 345 ? 181.438 177.727 130.636 1.00 145.24 ? 368 GLN C C   1 
ATOM   8703  O O   . GLN C 3 345 ? 180.268 178.005 130.354 1.00 145.24 ? 368 GLN C O   1 
ATOM   8704  C CB  . GLN C 3 345 ? 181.456 176.700 132.920 1.00 145.24 ? 368 GLN C CB  1 
ATOM   8705  C CG  . GLN C 3 345 ? 181.935 175.340 132.440 1.00 145.24 ? 368 GLN C CG  1 
ATOM   8706  C CD  . GLN C 3 345 ? 181.412 174.204 133.296 1.00 145.24 ? 368 GLN C CD  1 
ATOM   8707  O OE1 . GLN C 3 345 ? 180.670 174.423 134.252 1.00 145.24 ? 368 GLN C OE1 1 
ATOM   8708  N NE2 . GLN C 3 345 ? 181.799 172.980 132.954 1.00 145.24 ? 368 GLN C NE2 1 
ATOM   8709  N N   . TYR C 3 346 ? 182.324 177.292 129.743 1.00 161.33 ? 369 TYR C N   1 
ATOM   8710  C CA  . TYR C 3 346 ? 181.968 177.035 128.354 1.00 161.33 ? 369 TYR C CA  1 
ATOM   8711  C C   . TYR C 3 346 ? 182.843 175.904 127.837 1.00 161.33 ? 369 TYR C C   1 
ATOM   8712  O O   . TYR C 3 346 ? 184.072 175.977 127.928 1.00 161.33 ? 369 TYR C O   1 
ATOM   8713  C CB  . TYR C 3 346 ? 182.133 178.292 127.489 1.00 161.33 ? 369 TYR C CB  1 
ATOM   8714  C CG  . TYR C 3 346 ? 183.547 178.828 127.414 1.00 161.33 ? 369 TYR C CG  1 
ATOM   8715  C CD1 . TYR C 3 346 ? 184.091 179.562 128.460 1.00 161.33 ? 369 TYR C CD1 1 
ATOM   8716  C CD2 . TYR C 3 346 ? 184.336 178.604 126.292 1.00 161.33 ? 369 TYR C CD2 1 
ATOM   8717  C CE1 . TYR C 3 346 ? 185.382 180.053 128.394 1.00 161.33 ? 369 TYR C CE1 1 
ATOM   8718  C CE2 . TYR C 3 346 ? 185.627 179.091 126.217 1.00 161.33 ? 369 TYR C CE2 1 
ATOM   8719  C CZ  . TYR C 3 346 ? 186.145 179.815 127.270 1.00 161.33 ? 369 TYR C CZ  1 
ATOM   8720  O OH  . TYR C 3 346 ? 187.429 180.303 127.200 1.00 161.33 ? 369 TYR C OH  1 
ATOM   8721  N N   . GLY C 3 347 ? 182.208 174.860 127.309 1.00 163.87 ? 370 GLY C N   1 
ATOM   8722  C CA  . GLY C 3 347 ? 182.938 173.698 126.842 1.00 163.87 ? 370 GLY C CA  1 
ATOM   8723  C C   . GLY C 3 347 ? 183.722 173.026 127.950 1.00 163.87 ? 370 GLY C C   1 
ATOM   8724  O O   . GLY C 3 347 ? 183.142 172.395 128.838 1.00 163.87 ? 370 GLY C O   1 
ATOM   8725  N N   . GLU C 3 348 ? 185.048 173.156 127.907 1.00 162.57 ? 371 GLU C N   1 
ATOM   8726  C CA  . GLU C 3 348 ? 185.916 172.619 128.943 1.00 162.57 ? 371 GLU C CA  1 
ATOM   8727  C C   . GLU C 3 348 ? 186.655 173.693 129.728 1.00 162.57 ? 371 GLU C C   1 
ATOM   8728  O O   . GLU C 3 348 ? 187.320 173.364 130.716 1.00 162.57 ? 371 GLU C O   1 
ATOM   8729  C CB  . GLU C 3 348 ? 186.938 171.648 128.332 1.00 162.57 ? 371 GLU C CB  1 
ATOM   8730  C CG  . GLU C 3 348 ? 186.328 170.367 127.787 1.00 162.57 ? 371 GLU C CG  1 
ATOM   8731  C CD  . GLU C 3 348 ? 185.855 169.432 128.883 1.00 162.57 ? 371 GLU C CD  1 
ATOM   8732  O OE1 . GLU C 3 348 ? 186.345 169.556 130.026 1.00 162.57 ? 371 GLU C OE1 1 
ATOM   8733  O OE2 . GLU C 3 348 ? 184.993 168.573 128.603 1.00 162.57 ? 371 GLU C OE2 1 
ATOM   8734  N N   . VAL C 3 349 ? 186.558 174.953 129.322 1.00 158.44 ? 372 VAL C N   1 
ATOM   8735  C CA  . VAL C 3 349 ? 187.226 176.053 130.008 1.00 158.44 ? 372 VAL C CA  1 
ATOM   8736  C C   . VAL C 3 349 ? 186.289 176.622 131.062 1.00 158.44 ? 372 VAL C C   1 
ATOM   8737  O O   . VAL C 3 349 ? 185.097 176.832 130.808 1.00 158.44 ? 372 VAL C O   1 
ATOM   8738  C CB  . VAL C 3 349 ? 187.664 177.138 129.007 1.00 158.44 ? 372 VAL C CB  1 
ATOM   8739  C CG1 . VAL C 3 349 ? 188.648 178.097 129.660 1.00 158.44 ? 372 VAL C CG1 1 
ATOM   8740  C CG2 . VAL C 3 349 ? 188.272 176.501 127.767 1.00 158.44 ? 372 VAL C CG2 1 
ATOM   8741  N N   . ILE C 3 350 ? 186.828 176.873 132.252 1.00 141.43 ? 373 ILE C N   1 
ATOM   8742  C CA  . ILE C 3 350 ? 186.068 177.415 133.372 1.00 141.43 ? 373 ILE C CA  1 
ATOM   8743  C C   . ILE C 3 350 ? 186.739 178.703 133.827 1.00 141.43 ? 373 ILE C C   1 
ATOM   8744  O O   . ILE C 3 350 ? 187.947 178.719 134.092 1.00 141.43 ? 373 ILE C O   1 
ATOM   8745  C CB  . ILE C 3 350 ? 185.968 176.408 134.531 1.00 141.43 ? 373 ILE C CB  1 
ATOM   8746  C CG1 . ILE C 3 350 ? 185.254 175.136 134.071 1.00 141.43 ? 373 ILE C CG1 1 
ATOM   8747  C CG2 . ILE C 3 350 ? 185.244 177.027 135.715 1.00 141.43 ? 373 ILE C CG2 1 
ATOM   8748  C CD1 . ILE C 3 350 ? 185.106 174.092 135.155 1.00 141.43 ? 373 ILE C CD1 1 
ATOM   8749  N N   . HIS C 3 351 ? 185.957 179.777 133.916 1.00 132.74 ? 374 HIS C N   1 
ATOM   8750  C CA  . HIS C 3 351 ? 186.447 181.088 134.322 1.00 132.74 ? 374 HIS C CA  1 
ATOM   8751  C C   . HIS C 3 351 ? 185.729 181.504 135.597 1.00 132.74 ? 374 HIS C C   1 
ATOM   8752  O O   . HIS C 3 351 ? 184.504 181.667 135.597 1.00 132.74 ? 374 HIS C O   1 
ATOM   8753  C CB  . HIS C 3 351 ? 186.228 182.121 133.216 1.00 132.74 ? 374 HIS C CB  1 
ATOM   8754  C CG  . HIS C 3 351 ? 187.145 183.301 133.299 1.00 132.74 ? 374 HIS C CG  1 
ATOM   8755  N ND1 . HIS C 3 351 ? 188.509 183.197 133.129 1.00 132.74 ? 374 HIS C ND1 1 
ATOM   8756  C CD2 . HIS C 3 351 ? 186.894 184.611 133.531 1.00 132.74 ? 374 HIS C CD2 1 
ATOM   8757  C CE1 . HIS C 3 351 ? 189.059 184.391 133.255 1.00 132.74 ? 374 HIS C CE1 1 
ATOM   8758  N NE2 . HIS C 3 351 ? 188.101 185.267 133.499 1.00 132.74 ? 374 HIS C NE2 1 
ATOM   8759  N N   . GLU C 3 352 ? 186.487 181.673 136.678 1.00 122.61 ? 375 GLU C N   1 
ATOM   8760  C CA  . GLU C 3 352 ? 185.933 182.031 137.974 1.00 122.61 ? 375 GLU C CA  1 
ATOM   8761  C C   . GLU C 3 352 ? 186.671 183.239 138.535 1.00 122.61 ? 375 GLU C C   1 
ATOM   8762  O O   . GLU C 3 352 ? 187.824 183.508 138.187 1.00 122.61 ? 375 GLU C O   1 
ATOM   8763  C CB  . GLU C 3 352 ? 186.014 180.859 138.962 1.00 122.61 ? 375 GLU C CB  1 
ATOM   8764  C CG  . GLU C 3 352 ? 185.480 179.547 138.411 1.00 122.61 ? 375 GLU C CG  1 
ATOM   8765  C CD  . GLU C 3 352 ? 185.523 178.425 139.428 1.00 122.61 ? 375 GLU C CD  1 
ATOM   8766  O OE1 . GLU C 3 352 ? 185.103 178.650 140.582 1.00 122.61 ? 375 GLU C OE1 1 
ATOM   8767  O OE2 . GLU C 3 352 ? 185.975 177.316 139.073 1.00 122.61 ? 375 GLU C OE2 1 
ATOM   8768  N N   . HIS C 3 353 ? 185.989 183.966 139.415 1.00 117.36 ? 376 HIS C N   1 
ATOM   8769  C CA  . HIS C 3 353 ? 186.542 185.166 140.030 1.00 117.36 ? 376 HIS C CA  1 
ATOM   8770  C C   . HIS C 3 353 ? 185.919 185.334 141.412 1.00 117.36 ? 376 HIS C C   1 
ATOM   8771  O O   . HIS C 3 353 ? 185.277 184.421 141.939 1.00 117.36 ? 376 HIS C O   1 
ATOM   8772  C CB  . HIS C 3 353 ? 186.304 186.391 139.138 1.00 117.36 ? 376 HIS C CB  1 
ATOM   8773  C CG  . HIS C 3 353 ? 187.372 186.610 138.113 1.00 117.36 ? 376 HIS C CG  1 
ATOM   8774  N ND1 . HIS C 3 353 ? 188.545 187.279 138.391 1.00 117.36 ? 376 HIS C ND1 1 
ATOM   8775  C CD2 . HIS C 3 353 ? 187.444 186.254 136.808 1.00 117.36 ? 376 HIS C CD2 1 
ATOM   8776  C CE1 . HIS C 3 353 ? 189.294 187.323 137.304 1.00 117.36 ? 376 HIS C CE1 1 
ATOM   8777  N NE2 . HIS C 3 353 ? 188.649 186.708 136.329 1.00 117.36 ? 376 HIS C NE2 1 
ATOM   8778  N N   . ASN C 3 354 ? 186.115 186.513 142.002 1.00 114.28 ? 377 ASN C N   1 
ATOM   8779  C CA  . ASN C 3 354 ? 185.563 186.849 143.307 1.00 114.28 ? 377 ASN C CA  1 
ATOM   8780  C C   . ASN C 3 354 ? 184.888 188.211 143.236 1.00 114.28 ? 377 ASN C C   1 
ATOM   8781  O O   . ASN C 3 354 ? 185.430 189.151 142.647 1.00 114.28 ? 377 ASN C O   1 
ATOM   8782  C CB  . ASN C 3 354 ? 186.650 186.865 144.387 1.00 114.28 ? 377 ASN C CB  1 
ATOM   8783  C CG  . ASN C 3 354 ? 187.001 185.478 144.883 1.00 114.28 ? 377 ASN C CG  1 
ATOM   8784  O OD1 . ASN C 3 354 ? 186.248 184.524 144.685 1.00 114.28 ? 377 ASN C OD1 1 
ATOM   8785  N ND2 . ASN C 3 354 ? 188.151 185.360 145.536 1.00 114.28 ? 377 ASN C ND2 1 
ATOM   8786  N N   . VAL C 3 355 ? 183.705 188.314 143.842 1.00 109.01 ? 378 VAL C N   1 
ATOM   8787  C CA  . VAL C 3 355 ? 182.939 189.553 143.857 1.00 109.01 ? 378 VAL C CA  1 
ATOM   8788  C C   . VAL C 3 355 ? 182.349 189.761 145.245 1.00 109.01 ? 378 VAL C C   1 
ATOM   8789  O O   . VAL C 3 355 ? 182.008 188.804 145.947 1.00 109.01 ? 378 VAL C O   1 
ATOM   8790  C CB  . VAL C 3 355 ? 181.821 189.557 142.789 1.00 109.01 ? 378 VAL C CB  1 
ATOM   8791  C CG1 . VAL C 3 355 ? 182.407 189.780 141.404 1.00 109.01 ? 378 VAL C CG1 1 
ATOM   8792  C CG2 . VAL C 3 355 ? 181.036 188.257 142.838 1.00 109.01 ? 378 VAL C CG2 1 
ATOM   8793  N N   . SER C 3 356 ? 182.233 191.027 145.637 1.00 108.70 ? 379 SER C N   1 
ATOM   8794  C CA  . SER C 3 356 ? 181.650 191.416 146.914 1.00 108.70 ? 379 SER C CA  1 
ATOM   8795  C C   . SER C 3 356 ? 180.468 192.340 146.659 1.00 108.70 ? 379 SER C C   1 
ATOM   8796  O O   . SER C 3 356 ? 180.605 193.347 145.957 1.00 108.70 ? 379 SER C O   1 
ATOM   8797  C CB  . SER C 3 356 ? 182.684 192.107 147.806 1.00 108.70 ? 379 SER C CB  1 
ATOM   8798  O OG  . SER C 3 356 ? 183.435 193.059 147.073 1.00 108.70 ? 379 SER C OG  1 
ATOM   8799  N N   . VAL C 3 357 ? 179.312 191.997 147.230 1.00 119.99 ? 380 VAL C N   1 
ATOM   8800  C CA  . VAL C 3 357 ? 178.083 192.750 147.024 1.00 119.99 ? 380 VAL C CA  1 
ATOM   8801  C C   . VAL C 3 357 ? 177.497 193.132 148.377 1.00 119.99 ? 380 VAL C C   1 
ATOM   8802  O O   . VAL C 3 357 ? 177.799 192.527 149.408 1.00 119.99 ? 380 VAL C O   1 
ATOM   8803  C CB  . VAL C 3 357 ? 177.045 191.959 146.197 1.00 119.99 ? 380 VAL C CB  1 
ATOM   8804  C CG1 . VAL C 3 357 ? 177.674 191.419 144.923 1.00 119.99 ? 380 VAL C CG1 1 
ATOM   8805  C CG2 . VAL C 3 357 ? 176.453 190.828 147.024 1.00 119.99 ? 380 VAL C CG2 1 
ATOM   8806  N N   . HIS C 3 358 ? 176.652 194.164 148.360 1.00 131.22 ? 381 HIS C N   1 
ATOM   8807  C CA  . HIS C 3 358 ? 175.904 194.584 149.541 1.00 131.22 ? 381 HIS C CA  1 
ATOM   8808  C C   . HIS C 3 358 ? 174.467 194.076 149.502 1.00 131.22 ? 381 HIS C C   1 
ATOM   8809  O O   . HIS C 3 358 ? 174.033 193.349 150.401 1.00 131.22 ? 381 HIS C O   1 
ATOM   8810  C CB  . HIS C 3 358 ? 175.926 196.113 149.665 1.00 131.22 ? 381 HIS C CB  1 
ATOM   8811  C CG  . HIS C 3 358 ? 177.269 196.674 150.013 1.00 131.22 ? 381 HIS C CG  1 
ATOM   8812  N ND1 . HIS C 3 358 ? 178.368 196.539 149.192 1.00 131.22 ? 381 HIS C ND1 1 
ATOM   8813  C CD2 . HIS C 3 358 ? 177.689 197.375 151.092 1.00 131.22 ? 381 HIS C CD2 1 
ATOM   8814  C CE1 . HIS C 3 358 ? 179.408 197.131 149.752 1.00 131.22 ? 381 HIS C CE1 1 
ATOM   8815  N NE2 . HIS C 3 358 ? 179.023 197.646 150.906 1.00 131.22 ? 381 HIS C NE2 1 
ATOM   8816  N N   . MET C 3 359 ? 173.723 194.448 148.474 1.00 141.46 ? 382 MET C N   1 
ATOM   8817  C CA  . MET C 3 359 ? 172.374 193.945 148.241 1.00 141.46 ? 382 MET C CA  1 
ATOM   8818  C C   . MET C 3 359 ? 172.185 193.420 146.827 1.00 141.46 ? 382 MET C C   1 
ATOM   8819  O O   . MET C 3 359 ? 171.477 192.427 146.637 1.00 141.46 ? 382 MET C O   1 
ATOM   8820  C CB  . MET C 3 359 ? 171.339 195.044 148.537 1.00 141.46 ? 382 MET C CB  1 
ATOM   8821  C CG  . MET C 3 359 ? 171.607 196.363 147.829 1.00 141.46 ? 382 MET C CG  1 
ATOM   8822  S SD  . MET C 3 359 ? 170.337 197.601 148.156 1.00 141.46 ? 382 MET C SD  1 
ATOM   8823  C CE  . MET C 3 359 ? 170.926 198.963 147.154 1.00 141.46 ? 382 MET C CE  1 
ATOM   8824  N N   . SER C 3 360 ? 172.805 194.057 145.834 1.00 150.49 ? 383 SER C N   1 
ATOM   8825  C CA  . SER C 3 360 ? 172.720 193.625 144.445 1.00 150.49 ? 383 SER C CA  1 
ATOM   8826  C C   . SER C 3 360 ? 173.792 194.317 143.614 1.00 150.49 ? 383 SER C C   1 
ATOM   8827  O O   . SER C 3 360 ? 173.934 195.542 143.670 1.00 150.49 ? 383 SER C O   1 
ATOM   8828  C CB  . SER C 3 360 ? 171.332 193.916 143.869 1.00 150.49 ? 383 SER C CB  1 
ATOM   8829  O OG  . SER C 3 360 ? 171.245 193.501 142.517 1.00 150.49 ? 383 SER C OG  1 
ATOM   8830  N N   . ALA C 3 361 ? 174.551 193.544 142.841 1.00 155.64 ? 384 ALA C N   1 
ATOM   8831  C CA  . ALA C 3 361 ? 175.595 194.101 141.994 1.00 155.64 ? 384 ALA C CA  1 
ATOM   8832  C C   . ALA C 3 361 ? 175.735 193.234 140.752 1.00 155.64 ? 384 ALA C C   1 
ATOM   8833  O O   . ALA C 3 361 ? 175.126 192.167 140.639 1.00 155.64 ? 384 ALA C O   1 
ATOM   8834  C CB  . ALA C 3 361 ? 176.928 194.211 142.740 1.00 155.64 ? 384 ALA C CB  1 
ATOM   8835  N N   . ASN C 3 362 ? 176.550 193.707 139.815 1.00 164.70 ? 385 ASN C N   1 
ATOM   8836  C CA  . ASN C 3 362 ? 176.757 193.041 138.540 1.00 164.70 ? 385 ASN C CA  1 
ATOM   8837  C C   . ASN C 3 362 ? 178.238 192.747 138.334 1.00 164.70 ? 385 ASN C C   1 
ATOM   8838  O O   . ASN C 3 362 ? 179.097 193.165 139.113 1.00 164.70 ? 385 ASN C O   1 
ATOM   8839  C CB  . ASN C 3 362 ? 176.218 193.890 137.382 1.00 164.70 ? 385 ASN C CB  1 
ATOM   8840  C CG  . ASN C 3 362 ? 174.737 194.187 137.518 1.00 164.70 ? 385 ASN C CG  1 
ATOM   8841  O OD1 . ASN C 3 362 ? 174.008 193.467 138.201 1.00 164.70 ? 385 ASN C OD1 1 
ATOM   8842  N ND2 . ASN C 3 362 ? 174.284 195.251 136.865 1.00 164.70 ? 385 ASN C ND2 1 
ATOM   8843  N N   . TYR C 3 363 ? 178.526 192.012 137.261 1.00 154.47 ? 386 TYR C N   1 
ATOM   8844  C CA  . TYR C 3 363 ? 179.893 191.653 136.896 1.00 154.47 ? 386 TYR C CA  1 
ATOM   8845  C C   . TYR C 3 363 ? 179.995 191.686 135.379 1.00 154.47 ? 386 TYR C C   1 
ATOM   8846  O O   . TYR C 3 363 ? 179.447 190.812 134.699 1.00 154.47 ? 386 TYR C O   1 
ATOM   8847  C CB  . TYR C 3 363 ? 180.269 190.276 137.444 1.00 154.47 ? 386 TYR C CB  1 
ATOM   8848  C CG  . TYR C 3 363 ? 181.691 189.861 137.144 1.00 154.47 ? 386 TYR C CG  1 
ATOM   8849  C CD1 . TYR C 3 363 ? 181.969 188.936 136.146 1.00 154.47 ? 386 TYR C CD1 1 
ATOM   8850  C CD2 . TYR C 3 363 ? 182.756 190.393 137.858 1.00 154.47 ? 386 TYR C CD2 1 
ATOM   8851  C CE1 . TYR C 3 363 ? 183.268 188.552 135.869 1.00 154.47 ? 386 TYR C CE1 1 
ATOM   8852  C CE2 . TYR C 3 363 ? 184.058 190.016 137.588 1.00 154.47 ? 386 TYR C CE2 1 
ATOM   8853  C CZ  . TYR C 3 363 ? 184.308 189.096 136.593 1.00 154.47 ? 386 TYR C CZ  1 
ATOM   8854  O OH  . TYR C 3 363 ? 185.602 188.717 136.320 1.00 154.47 ? 386 TYR C OH  1 
ATOM   8855  N N   . LEU C 3 364 ? 180.695 192.687 134.850 1.00 159.86 ? 387 LEU C N   1 
ATOM   8856  C CA  . LEU C 3 364 ? 180.796 192.885 133.407 1.00 159.86 ? 387 LEU C CA  1 
ATOM   8857  C C   . LEU C 3 364 ? 181.775 191.874 132.824 1.00 159.86 ? 387 LEU C C   1 
ATOM   8858  O O   . LEU C 3 364 ? 182.975 191.923 133.110 1.00 159.86 ? 387 LEU C O   1 
ATOM   8859  C CB  . LEU C 3 364 ? 181.236 194.312 133.092 1.00 159.86 ? 387 LEU C CB  1 
ATOM   8860  C CG  . LEU C 3 364 ? 180.287 195.443 133.492 1.00 159.86 ? 387 LEU C CG  1 
ATOM   8861  C CD1 . LEU C 3 364 ? 180.618 195.963 134.883 1.00 159.86 ? 387 LEU C CD1 1 
ATOM   8862  C CD2 . LEU C 3 364 ? 180.338 196.567 132.469 1.00 159.86 ? 387 LEU C CD2 1 
ATOM   8863  N N   . PHE C 3 365 ? 181.266 190.958 132.006 1.00 164.84 ? 388 PHE C N   1 
ATOM   8864  C CA  . PHE C 3 365 ? 182.118 189.998 131.323 1.00 164.84 ? 388 PHE C CA  1 
ATOM   8865  C C   . PHE C 3 365 ? 182.693 190.609 130.051 1.00 164.84 ? 388 PHE C C   1 
ATOM   8866  O O   . PHE C 3 365 ? 182.088 191.486 129.428 1.00 164.84 ? 388 PHE C O   1 
ATOM   8867  C CB  . PHE C 3 365 ? 181.336 188.729 130.984 1.00 164.84 ? 388 PHE C CB  1 
ATOM   8868  C CG  . PHE C 3 365 ? 180.789 188.015 132.185 1.00 164.84 ? 388 PHE C CG  1 
ATOM   8869  C CD1 . PHE C 3 365 ? 181.554 187.077 132.858 1.00 164.84 ? 388 PHE C CD1 1 
ATOM   8870  C CD2 . PHE C 3 365 ? 179.509 188.281 132.641 1.00 164.84 ? 388 PHE C CD2 1 
ATOM   8871  C CE1 . PHE C 3 365 ? 181.052 186.418 133.963 1.00 164.84 ? 388 PHE C CE1 1 
ATOM   8872  C CE2 . PHE C 3 365 ? 179.003 187.625 133.745 1.00 164.84 ? 388 PHE C CE2 1 
ATOM   8873  C CZ  . PHE C 3 365 ? 179.775 186.693 134.407 1.00 164.84 ? 388 PHE C CZ  1 
ATOM   8874  N N   . SER C 3 366 ? 183.877 190.136 129.670 1.00 177.83 ? 389 SER C N   1 
ATOM   8875  C CA  . SER C 3 366 ? 184.560 190.628 128.483 1.00 177.83 ? 389 SER C CA  1 
ATOM   8876  C C   . SER C 3 366 ? 185.287 189.474 127.807 1.00 177.83 ? 389 SER C C   1 
ATOM   8877  O O   . SER C 3 366 ? 185.469 188.399 128.386 1.00 177.83 ? 389 SER C O   1 
ATOM   8878  C CB  . SER C 3 366 ? 185.541 191.757 128.825 1.00 177.83 ? 389 SER C CB  1 
ATOM   8879  O OG  . SER C 3 366 ? 184.951 192.696 129.707 1.00 177.83 ? 389 SER C OG  1 
ATOM   8880  N N   . ASP C 3 367 ? 185.700 189.715 126.560 1.00 186.78 ? 390 ASP C N   1 
ATOM   8881  C CA  . ASP C 3 367 ? 186.458 188.746 125.766 1.00 186.78 ? 390 ASP C CA  1 
ATOM   8882  C C   . ASP C 3 367 ? 185.694 187.430 125.617 1.00 186.78 ? 390 ASP C C   1 
ATOM   8883  O O   . ASP C 3 367 ? 186.218 186.345 125.878 1.00 186.78 ? 390 ASP C O   1 
ATOM   8884  C CB  . ASP C 3 367 ? 187.847 188.512 126.365 1.00 186.78 ? 390 ASP C CB  1 
ATOM   8885  C CG  . ASP C 3 367 ? 188.646 189.793 126.500 1.00 186.78 ? 390 ASP C CG  1 
ATOM   8886  O OD1 . ASP C 3 367 ? 188.413 190.727 125.705 1.00 186.78 ? 390 ASP C OD1 1 
ATOM   8887  O OD2 . ASP C 3 367 ? 189.507 189.866 127.402 1.00 186.78 ? 390 ASP C OD2 1 
ATOM   8888  N N   . LEU C 3 368 ? 184.440 187.536 125.190 1.00 192.64 ? 391 LEU C N   1 
ATOM   8889  C CA  . LEU C 3 368 ? 183.608 186.367 124.954 1.00 192.64 ? 391 LEU C CA  1 
ATOM   8890  C C   . LEU C 3 368 ? 183.689 185.944 123.492 1.00 192.64 ? 391 LEU C C   1 
ATOM   8891  O O   . LEU C 3 368 ? 183.821 186.775 122.590 1.00 192.64 ? 391 LEU C O   1 
ATOM   8892  C CB  . LEU C 3 368 ? 182.154 186.649 125.336 1.00 192.64 ? 391 LEU C CB  1 
ATOM   8893  C CG  . LEU C 3 368 ? 181.911 187.102 126.777 1.00 192.64 ? 391 LEU C CG  1 
ATOM   8894  C CD1 . LEU C 3 368 ? 180.427 187.320 127.028 1.00 192.64 ? 391 LEU C CD1 1 
ATOM   8895  C CD2 . LEU C 3 368 ? 182.483 186.094 127.761 1.00 192.64 ? 391 LEU C CD2 1 
ATOM   8896  N N   . ASP C 3 369 ? 183.609 184.635 123.268 1.00 199.08 ? 392 ASP C N   1 
ATOM   8897  C CA  . ASP C 3 369 ? 183.696 184.142 121.899 1.00 199.08 ? 392 ASP C CA  1 
ATOM   8898  C C   . ASP C 3 369 ? 182.310 184.090 121.262 1.00 199.08 ? 392 ASP C C   1 
ATOM   8899  O O   . ASP C 3 369 ? 181.350 183.647 121.901 1.00 199.08 ? 392 ASP C O   1 
ATOM   8900  C CB  . ASP C 3 369 ? 184.325 182.753 121.863 1.00 199.08 ? 392 ASP C CB  1 
ATOM   8901  C CG  . ASP C 3 369 ? 185.682 182.712 122.537 1.00 199.08 ? 392 ASP C CG  1 
ATOM   8902  O OD1 . ASP C 3 369 ? 186.385 183.744 122.524 1.00 199.08 ? 392 ASP C OD1 1 
ATOM   8903  O OD2 . ASP C 3 369 ? 186.046 181.647 123.080 1.00 199.08 ? 392 ASP C OD2 1 
ATOM   8904  N N   . PRO C 3 370 ? 182.184 184.537 120.015 1.00 206.56 ? 393 PRO C N   1 
ATOM   8905  C CA  . PRO C 3 370 ? 180.882 184.497 119.340 1.00 206.56 ? 393 PRO C CA  1 
ATOM   8906  C C   . PRO C 3 370 ? 180.442 183.066 119.067 1.00 206.56 ? 393 PRO C C   1 
ATOM   8907  O O   . PRO C 3 370 ? 181.219 182.114 119.163 1.00 206.56 ? 393 PRO C O   1 
ATOM   8908  C CB  . PRO C 3 370 ? 181.127 185.265 118.035 1.00 206.56 ? 393 PRO C CB  1 
ATOM   8909  C CG  . PRO C 3 370 ? 182.400 186.031 118.261 1.00 206.56 ? 393 PRO C CG  1 
ATOM   8910  C CD  . PRO C 3 370 ? 183.213 185.192 119.193 1.00 206.56 ? 393 PRO C CD  1 
ATOM   8911  N N   . ASP C 3 371 ? 179.164 182.941 118.702 1.00 205.59 ? 394 ASP C N   1 
ATOM   8912  C CA  . ASP C 3 371 ? 178.500 181.664 118.415 1.00 205.59 ? 394 ASP C CA  1 
ATOM   8913  C C   . ASP C 3 371 ? 178.929 180.571 119.393 1.00 205.59 ? 394 ASP C C   1 
ATOM   8914  O O   . ASP C 3 371 ? 179.350 179.477 119.010 1.00 205.59 ? 394 ASP C O   1 
ATOM   8915  C CB  . ASP C 3 371 ? 178.725 181.230 116.961 1.00 205.59 ? 394 ASP C CB  1 
ATOM   8916  C CG  . ASP C 3 371 ? 180.193 181.145 116.583 1.00 205.59 ? 394 ASP C CG  1 
ATOM   8917  O OD1 . ASP C 3 371 ? 180.778 182.187 116.219 1.00 205.59 ? 394 ASP C OD1 1 
ATOM   8918  O OD2 . ASP C 3 371 ? 180.763 180.035 116.645 1.00 205.59 ? 394 ASP C OD2 1 
ATOM   8919  N N   . THR C 3 372 ? 178.807 180.880 120.682 1.00 203.22 ? 395 THR C N   1 
ATOM   8920  C CA  . THR C 3 372 ? 179.193 179.958 121.742 1.00 203.22 ? 395 THR C CA  1 
ATOM   8921  C C   . THR C 3 372 ? 178.189 180.058 122.879 1.00 203.22 ? 395 THR C C   1 
ATOM   8922  O O   . THR C 3 372 ? 177.866 181.161 123.329 1.00 203.22 ? 395 THR C O   1 
ATOM   8923  C CB  . THR C 3 372 ? 180.606 180.262 122.256 1.00 203.22 ? 395 THR C CB  1 
ATOM   8924  O OG1 . THR C 3 372 ? 181.548 180.110 121.187 1.00 203.22 ? 395 THR C OG1 1 
ATOM   8925  C CG2 . THR C 3 372 ? 180.979 179.319 123.391 1.00 203.22 ? 395 THR C CG2 1 
ATOM   8926  N N   . LYS C 3 373 ? 177.697 178.909 123.336 1.00 191.88 ? 396 LYS C N   1 
ATOM   8927  C CA  . LYS C 3 373 ? 176.758 178.873 124.449 1.00 191.88 ? 396 LYS C CA  1 
ATOM   8928  C C   . LYS C 3 373 ? 177.517 178.885 125.770 1.00 191.88 ? 396 LYS C C   1 
ATOM   8929  O O   . LYS C 3 373 ? 178.438 178.088 125.975 1.00 191.88 ? 396 LYS C O   1 
ATOM   8930  C CB  . LYS C 3 373 ? 175.869 177.634 124.358 1.00 191.88 ? 396 LYS C CB  1 
ATOM   8931  C CG  . LYS C 3 373 ? 174.884 177.493 125.506 1.00 191.88 ? 396 LYS C CG  1 
ATOM   8932  C CD  . LYS C 3 373 ? 174.059 176.225 125.372 1.00 191.88 ? 396 LYS C CD  1 
ATOM   8933  C CE  . LYS C 3 373 ? 173.096 176.069 126.537 1.00 191.88 ? 396 LYS C CE  1 
ATOM   8934  N NZ  . LYS C 3 373 ? 172.288 174.822 126.430 1.00 191.88 ? 396 LYS C NZ  1 
ATOM   8935  N N   . TYR C 3 374 ? 177.130 179.791 126.664 1.00 184.22 ? 397 TYR C N   1 
ATOM   8936  C CA  . TYR C 3 374 ? 177.782 179.950 127.954 1.00 184.22 ? 397 TYR C CA  1 
ATOM   8937  C C   . TYR C 3 374 ? 176.815 179.601 129.077 1.00 184.22 ? 397 TYR C C   1 
ATOM   8938  O O   . TYR C 3 374 ? 175.598 179.756 128.944 1.00 184.22 ? 397 TYR C O   1 
ATOM   8939  C CB  . TYR C 3 374 ? 178.300 181.381 128.141 1.00 184.22 ? 397 TYR C CB  1 
ATOM   8940  C CG  . TYR C 3 374 ? 179.432 181.749 127.209 1.00 184.22 ? 397 TYR C CG  1 
ATOM   8941  C CD1 . TYR C 3 374 ? 180.754 181.529 127.572 1.00 184.22 ? 397 TYR C CD1 1 
ATOM   8942  C CD2 . TYR C 3 374 ? 179.179 182.315 125.968 1.00 184.22 ? 397 TYR C CD2 1 
ATOM   8943  C CE1 . TYR C 3 374 ? 181.792 181.862 126.724 1.00 184.22 ? 397 TYR C CE1 1 
ATOM   8944  C CE2 . TYR C 3 374 ? 180.211 182.652 125.113 1.00 184.22 ? 397 TYR C CE2 1 
ATOM   8945  C CZ  . TYR C 3 374 ? 181.515 182.423 125.497 1.00 184.22 ? 397 TYR C CZ  1 
ATOM   8946  O OH  . TYR C 3 374 ? 182.546 182.756 124.650 1.00 184.22 ? 397 TYR C OH  1 
ATOM   8947  N N   . LYS C 3 375 ? 177.374 179.127 130.189 1.00 158.19 ? 398 LYS C N   1 
ATOM   8948  C CA  . LYS C 3 375 ? 176.604 178.769 131.372 1.00 158.19 ? 398 LYS C CA  1 
ATOM   8949  C C   . LYS C 3 375 ? 177.183 179.495 132.575 1.00 158.19 ? 398 LYS C C   1 
ATOM   8950  O O   . LYS C 3 375 ? 178.381 179.381 132.855 1.00 158.19 ? 398 LYS C O   1 
ATOM   8951  C CB  . LYS C 3 375 ? 176.617 177.255 131.609 1.00 158.19 ? 398 LYS C CB  1 
ATOM   8952  C CG  . LYS C 3 375 ? 176.104 176.437 130.436 1.00 158.19 ? 398 LYS C CG  1 
ATOM   8953  C CD  . LYS C 3 375 ? 176.189 174.947 130.725 1.00 158.19 ? 398 LYS C CD  1 
ATOM   8954  C CE  . LYS C 3 375 ? 175.778 174.126 129.514 1.00 158.19 ? 398 LYS C CE  1 
ATOM   8955  N NZ  . LYS C 3 375 ? 175.827 172.665 129.793 1.00 158.19 ? 398 LYS C NZ  1 
ATOM   8956  N N   . ALA C 3 376 ? 176.336 180.238 133.281 1.00 143.00 ? 399 ALA C N   1 
ATOM   8957  C CA  . ALA C 3 376 ? 176.754 181.018 134.436 1.00 143.00 ? 399 ALA C CA  1 
ATOM   8958  C C   . ALA C 3 376 ? 176.370 180.304 135.725 1.00 143.00 ? 399 ALA C C   1 
ATOM   8959  O O   . ALA C 3 376 ? 175.256 179.788 135.855 1.00 143.00 ? 399 ALA C O   1 
ATOM   8960  C CB  . ALA C 3 376 ? 176.128 182.414 134.407 1.00 143.00 ? 399 ALA C CB  1 
ATOM   8961  N N   . PHE C 3 377 ? 177.301 180.277 136.676 1.00 131.47 ? 400 PHE C N   1 
ATOM   8962  C CA  . PHE C 3 377 ? 177.081 179.675 137.985 1.00 131.47 ? 400 PHE C CA  1 
ATOM   8963  C C   . PHE C 3 377 ? 177.465 180.690 139.049 1.00 131.47 ? 400 PHE C C   1 
ATOM   8964  O O   . PHE C 3 377 ? 178.612 181.148 139.085 1.00 131.47 ? 400 PHE C O   1 
ATOM   8965  C CB  . PHE C 3 377 ? 177.893 178.387 138.149 1.00 131.47 ? 400 PHE C CB  1 
ATOM   8966  C CG  . PHE C 3 377 ? 177.518 177.305 137.179 1.00 131.47 ? 400 PHE C CG  1 
ATOM   8967  C CD1 . PHE C 3 377 ? 176.443 176.469 137.434 1.00 131.47 ? 400 PHE C CD1 1 
ATOM   8968  C CD2 . PHE C 3 377 ? 178.242 177.119 136.014 1.00 131.47 ? 400 PHE C CD2 1 
ATOM   8969  C CE1 . PHE C 3 377 ? 176.096 175.471 136.544 1.00 131.47 ? 400 PHE C CE1 1 
ATOM   8970  C CE2 . PHE C 3 377 ? 177.900 176.123 135.120 1.00 131.47 ? 400 PHE C CE2 1 
ATOM   8971  C CZ  . PHE C 3 377 ? 176.826 175.298 135.385 1.00 131.47 ? 400 PHE C CZ  1 
ATOM   8972  N N   . VAL C 3 378 ? 176.512 181.044 139.909 1.00 120.68 ? 401 VAL C N   1 
ATOM   8973  C CA  . VAL C 3 378 ? 176.715 182.057 140.937 1.00 120.68 ? 401 VAL C CA  1 
ATOM   8974  C C   . VAL C 3 378 ? 176.291 181.485 142.282 1.00 120.68 ? 401 VAL C C   1 
ATOM   8975  O O   . VAL C 3 378 ? 175.204 180.909 142.402 1.00 120.68 ? 401 VAL C O   1 
ATOM   8976  C CB  . VAL C 3 378 ? 175.932 183.350 140.633 1.00 120.68 ? 401 VAL C CB  1 
ATOM   8977  C CG1 . VAL C 3 378 ? 176.252 184.418 141.667 1.00 120.68 ? 401 VAL C CG1 1 
ATOM   8978  C CG2 . VAL C 3 378 ? 176.245 183.851 139.231 1.00 120.68 ? 401 VAL C CG2 1 
ATOM   8979  N N   . ARG C 3 379 ? 177.149 181.644 143.287 1.00 110.77 ? 402 ARG C N   1 
ATOM   8980  C CA  . ARG C 3 379 ? 176.829 181.287 144.661 1.00 110.77 ? 402 ARG C CA  1 
ATOM   8981  C C   . ARG C 3 379 ? 177.468 182.310 145.588 1.00 110.77 ? 402 ARG C C   1 
ATOM   8982  O O   . ARG C 3 379 ? 178.467 182.945 145.239 1.00 110.77 ? 402 ARG C O   1 
ATOM   8983  C CB  . ARG C 3 379 ? 177.310 179.873 145.014 1.00 110.77 ? 402 ARG C CB  1 
ATOM   8984  C CG  . ARG C 3 379 ? 178.817 179.742 145.149 1.00 110.77 ? 402 ARG C CG  1 
ATOM   8985  C CD  . ARG C 3 379 ? 179.197 178.448 145.846 1.00 110.77 ? 402 ARG C CD  1 
ATOM   8986  N NE  . ARG C 3 379 ? 180.644 178.291 145.949 1.00 110.77 ? 402 ARG C NE  1 
ATOM   8987  C CZ  . ARG C 3 379 ? 181.244 177.227 146.473 1.00 110.77 ? 402 ARG C CZ  1 
ATOM   8988  N NH1 . ARG C 3 379 ? 180.521 176.220 146.942 1.00 110.77 ? 402 ARG C NH1 1 
ATOM   8989  N NH2 . ARG C 3 379 ? 182.567 177.169 146.526 1.00 110.77 ? 402 ARG C NH2 1 
ATOM   8990  N N   . CYS C 3 380 ? 176.883 182.469 146.772 1.00 107.05 ? 403 CYS C N   1 
ATOM   8991  C CA  . CYS C 3 380 ? 177.322 183.483 147.717 1.00 107.05 ? 403 CYS C CA  1 
ATOM   8992  C C   . CYS C 3 380 ? 177.551 182.864 149.088 1.00 107.05 ? 403 CYS C C   1 
ATOM   8993  O O   . CYS C 3 380 ? 177.047 181.782 149.401 1.00 107.05 ? 403 CYS C O   1 
ATOM   8994  C CB  . CYS C 3 380 ? 176.303 184.626 147.826 1.00 107.05 ? 403 CYS C CB  1 
ATOM   8995  S SG  . CYS C 3 380 ? 175.980 185.489 146.270 1.00 107.05 ? 403 CYS C SG  1 
ATOM   8996  N N   . ALA C 3 381 ? 178.325 183.574 149.904 1.00 97.00  ? 404 ALA C N   1 
ATOM   8997  C CA  . ALA C 3 381 ? 178.602 183.166 151.274 1.00 97.00  ? 404 ALA C CA  1 
ATOM   8998  C C   . ALA C 3 381 ? 179.041 184.395 152.055 1.00 97.00  ? 404 ALA C C   1 
ATOM   8999  O O   . ALA C 3 381 ? 179.276 185.465 151.487 1.00 97.00  ? 404 ALA C O   1 
ATOM   9000  C CB  . ALA C 3 381 ? 179.666 182.066 151.331 1.00 97.00  ? 404 ALA C CB  1 
ATOM   9001  N N   . SER C 3 382 ? 179.156 184.227 153.371 1.00 82.53  ? 405 SER C N   1 
ATOM   9002  C CA  . SER C 3 382 ? 179.541 185.336 154.233 1.00 82.53  ? 405 SER C CA  1 
ATOM   9003  C C   . SER C 3 382 ? 180.954 185.804 153.904 1.00 82.53  ? 405 SER C C   1 
ATOM   9004  O O   . SER C 3 382 ? 181.820 185.018 153.510 1.00 82.53  ? 405 SER C O   1 
ATOM   9005  C CB  . SER C 3 382 ? 179.448 184.925 155.702 1.00 82.53  ? 405 SER C CB  1 
ATOM   9006  O OG  . SER C 3 382 ? 178.099 184.874 156.131 1.00 82.53  ? 405 SER C OG  1 
ATOM   9007  N N   . ALA C 3 383 ? 181.184 187.107 154.071 1.00 79.64  ? 406 ALA C N   1 
ATOM   9008  C CA  . ALA C 3 383 ? 182.461 187.695 153.683 1.00 79.64  ? 406 ALA C CA  1 
ATOM   9009  C C   . ALA C 3 383 ? 183.530 187.472 154.748 1.00 79.64  ? 406 ALA C C   1 
ATOM   9010  O O   . ALA C 3 383 ? 184.552 186.827 154.491 1.00 79.64  ? 406 ALA C O   1 
ATOM   9011  C CB  . ALA C 3 383 ? 182.286 189.190 153.403 1.00 79.64  ? 406 ALA C CB  1 
ATOM   9012  N N   . ASN C 3 384 ? 183.308 187.998 155.952 1.00 86.67  ? 407 ASN C N   1 
ATOM   9013  C CA  . ASN C 3 384 ? 184.322 187.912 156.998 1.00 86.67  ? 407 ASN C CA  1 
ATOM   9014  C C   . ASN C 3 384 ? 184.315 186.543 157.670 1.00 86.67  ? 407 ASN C C   1 
ATOM   9015  O O   . ASN C 3 384 ? 185.315 185.817 157.637 1.00 86.67  ? 407 ASN C O   1 
ATOM   9016  C CB  . ASN C 3 384 ? 184.104 189.020 158.032 1.00 86.67  ? 407 ASN C CB  1 
ATOM   9017  C CG  . ASN C 3 384 ? 184.200 190.407 157.429 1.00 86.67  ? 407 ASN C CG  1 
ATOM   9018  O OD1 . ASN C 3 384 ? 183.287 191.221 157.567 1.00 86.67  ? 407 ASN C OD1 1 
ATOM   9019  N ND2 . ASN C 3 384 ? 185.309 190.683 156.752 1.00 86.67  ? 407 ASN C ND2 1 
ATOM   9020  N N   . HIS C 3 385 ? 183.194 186.173 158.283 1.00 74.88  ? 408 HIS C N   1 
ATOM   9021  C CA  . HIS C 3 385 ? 183.079 184.925 159.035 1.00 74.88  ? 408 HIS C CA  1 
ATOM   9022  C C   . HIS C 3 385 ? 182.318 183.922 158.174 1.00 74.88  ? 408 HIS C C   1 
ATOM   9023  O O   . HIS C 3 385 ? 181.098 183.789 158.269 1.00 74.88  ? 408 HIS C O   1 
ATOM   9024  C CB  . HIS C 3 385 ? 182.391 185.166 160.372 1.00 74.88  ? 408 HIS C CB  1 
ATOM   9025  C CG  . HIS C 3 385 ? 182.868 186.397 161.078 1.00 74.88  ? 408 HIS C CG  1 
ATOM   9026  N ND1 . HIS C 3 385 ? 183.967 186.399 161.910 1.00 74.88  ? 408 HIS C ND1 1 
ATOM   9027  C CD2 . HIS C 3 385 ? 182.399 187.667 161.071 1.00 74.88  ? 408 HIS C CD2 1 
ATOM   9028  C CE1 . HIS C 3 385 ? 184.153 187.617 162.387 1.00 74.88  ? 408 HIS C CE1 1 
ATOM   9029  N NE2 . HIS C 3 385 ? 183.215 188.405 161.894 1.00 74.88  ? 408 HIS C NE2 1 
ATOM   9030  N N   . PHE C 3 386 ? 183.056 183.207 157.329 1.00 81.19  ? 409 PHE C N   1 
ATOM   9031  C CA  . PHE C 3 386 ? 182.446 182.238 156.430 1.00 81.19  ? 409 PHE C CA  1 
ATOM   9032  C C   . PHE C 3 386 ? 181.945 181.030 157.211 1.00 81.19  ? 409 PHE C C   1 
ATOM   9033  O O   . PHE C 3 386 ? 182.673 180.458 158.028 1.00 81.19  ? 409 PHE C O   1 
ATOM   9034  C CB  . PHE C 3 386 ? 183.450 181.802 155.364 1.00 81.19  ? 409 PHE C CB  1 
ATOM   9035  C CG  . PHE C 3 386 ? 183.208 180.418 154.833 1.00 81.19  ? 409 PHE C CG  1 
ATOM   9036  C CD1 . PHE C 3 386 ? 184.049 179.373 155.177 1.00 81.19  ? 409 PHE C CD1 1 
ATOM   9037  C CD2 . PHE C 3 386 ? 182.141 180.163 153.987 1.00 81.19  ? 409 PHE C CD2 1 
ATOM   9038  C CE1 . PHE C 3 386 ? 183.829 178.099 154.690 1.00 81.19  ? 409 PHE C CE1 1 
ATOM   9039  C CE2 . PHE C 3 386 ? 181.917 178.891 153.497 1.00 81.19  ? 409 PHE C CE2 1 
ATOM   9040  C CZ  . PHE C 3 386 ? 182.762 177.858 153.849 1.00 81.19  ? 409 PHE C CZ  1 
ATOM   9041  N N   . TRP C 3 387 ? 180.696 180.641 156.956 1.00 70.34  ? 410 TRP C N   1 
ATOM   9042  C CA  . TRP C 3 387 ? 180.095 179.475 157.588 1.00 70.34  ? 410 TRP C CA  1 
ATOM   9043  C C   . TRP C 3 387 ? 179.794 178.374 156.579 1.00 70.34  ? 410 TRP C C   1 
ATOM   9044  O O   . TRP C 3 387 ? 180.261 177.243 156.739 1.00 70.34  ? 410 TRP C O   1 
ATOM   9045  C CB  . TRP C 3 387 ? 178.817 179.881 158.335 1.00 70.34  ? 410 TRP C CB  1 
ATOM   9046  C CG  . TRP C 3 387 ? 178.012 178.717 158.819 1.00 70.34  ? 410 TRP C CG  1 
ATOM   9047  C CD1 . TRP C 3 387 ? 176.920 178.168 158.215 1.00 70.34  ? 410 TRP C CD1 1 
ATOM   9048  C CD2 . TRP C 3 387 ? 178.234 177.956 160.013 1.00 70.34  ? 410 TRP C CD2 1 
ATOM   9049  N NE1 . TRP C 3 387 ? 176.448 177.113 158.956 1.00 70.34  ? 410 TRP C NE1 1 
ATOM   9050  C CE2 . TRP C 3 387 ? 177.237 176.962 160.065 1.00 70.34  ? 410 TRP C CE2 1 
ATOM   9051  C CE3 . TRP C 3 387 ? 179.179 178.019 161.041 1.00 70.34  ? 410 TRP C CE3 1 
ATOM   9052  C CZ2 . TRP C 3 387 ? 177.158 176.039 161.105 1.00 70.34  ? 410 TRP C CZ2 1 
ATOM   9053  C CZ3 . TRP C 3 387 ? 179.098 177.101 162.073 1.00 70.34  ? 410 TRP C CZ3 1 
ATOM   9054  C CH2 . TRP C 3 387 ? 178.096 176.125 162.097 1.00 70.34  ? 410 TRP C CH2 1 
ATOM   9055  N N   . LYS C 3 388 ? 179.029 178.680 155.533 1.00 77.99  ? 411 LYS C N   1 
ATOM   9056  C CA  . LYS C 3 388 ? 178.677 177.695 154.522 1.00 77.99  ? 411 LYS C CA  1 
ATOM   9057  C C   . LYS C 3 388 ? 178.471 178.400 153.190 1.00 77.99  ? 411 LYS C C   1 
ATOM   9058  O O   . LYS C 3 388 ? 178.335 179.624 153.127 1.00 77.99  ? 411 LYS C O   1 
ATOM   9059  C CB  . LYS C 3 388 ? 177.417 176.910 154.908 1.00 77.99  ? 411 LYS C CB  1 
ATOM   9060  C CG  . LYS C 3 388 ? 177.678 175.686 155.769 1.00 77.99  ? 411 LYS C CG  1 
ATOM   9061  C CD  . LYS C 3 388 ? 176.396 174.914 156.032 1.00 77.99  ? 411 LYS C CD  1 
ATOM   9062  C CE  . LYS C 3 388 ? 176.660 173.674 156.870 1.00 77.99  ? 411 LYS C CE  1 
ATOM   9063  N NZ  . LYS C 3 388 ? 175.419 172.883 157.098 1.00 77.99  ? 411 LYS C NZ  1 
ATOM   9064  N N   . TRP C 3 389 ? 178.450 177.608 152.123 1.00 90.81  ? 412 TRP C N   1 
ATOM   9065  C CA  . TRP C 3 389 ? 178.229 178.112 150.775 1.00 90.81  ? 412 TRP C CA  1 
ATOM   9066  C C   . TRP C 3 389 ? 176.778 177.892 150.370 1.00 90.81  ? 412 TRP C C   1 
ATOM   9067  O O   . TRP C 3 389 ? 176.160 176.894 150.749 1.00 90.81  ? 412 TRP C O   1 
ATOM   9068  C CB  . TRP C 3 389 ? 179.159 177.425 149.773 1.00 90.81  ? 412 TRP C CB  1 
ATOM   9069  C CG  . TRP C 3 389 ? 180.604 177.780 149.949 1.00 90.81  ? 412 TRP C CG  1 
ATOM   9070  C CD1 . TRP C 3 389 ? 181.545 177.065 150.629 1.00 90.81  ? 412 TRP C CD1 1 
ATOM   9071  C CD2 . TRP C 3 389 ? 181.273 178.936 149.433 1.00 90.81  ? 412 TRP C CD2 1 
ATOM   9072  N NE1 . TRP C 3 389 ? 182.759 177.705 150.570 1.00 90.81  ? 412 TRP C NE1 1 
ATOM   9073  C CE2 . TRP C 3 389 ? 182.619 178.857 149.842 1.00 90.81  ? 412 TRP C CE2 1 
ATOM   9074  C CE3 . TRP C 3 389 ? 180.866 180.031 148.666 1.00 90.81  ? 412 TRP C CE3 1 
ATOM   9075  C CZ2 . TRP C 3 389 ? 183.559 179.829 149.510 1.00 90.81  ? 412 TRP C CZ2 1 
ATOM   9076  C CZ3 . TRP C 3 389 ? 181.801 180.996 148.337 1.00 90.81  ? 412 TRP C CZ3 1 
ATOM   9077  C CH2 . TRP C 3 389 ? 183.131 180.889 148.759 1.00 90.81  ? 412 TRP C CH2 1 
ATOM   9078  N N   . SER C 3 390 ? 176.241 178.830 149.595 1.00 102.93 ? 413 SER C N   1 
ATOM   9079  C CA  . SER C 3 390 ? 174.863 178.749 149.132 1.00 102.93 ? 413 SER C CA  1 
ATOM   9080  C C   . SER C 3 390 ? 174.767 177.752 147.977 1.00 102.93 ? 413 SER C C   1 
ATOM   9081  O O   . SER C 3 390 ? 175.732 177.066 147.629 1.00 102.93 ? 413 SER C O   1 
ATOM   9082  C CB  . SER C 3 390 ? 174.357 180.133 148.736 1.00 102.93 ? 413 SER C CB  1 
ATOM   9083  O OG  . SER C 3 390 ? 175.324 180.830 147.971 1.00 102.93 ? 413 SER C OG  1 
ATOM   9084  N N   . ASP C 3 391 ? 173.589 177.664 147.369 1.00 119.47 ? 414 ASP C N   1 
ATOM   9085  C CA  . ASP C 3 391 ? 173.362 176.762 146.251 1.00 119.47 ? 414 ASP C CA  1 
ATOM   9086  C C   . ASP C 3 391 ? 173.732 177.437 144.936 1.00 119.47 ? 414 ASP C C   1 
ATOM   9087  O O   . ASP C 3 391 ? 173.661 178.661 144.800 1.00 119.47 ? 414 ASP C O   1 
ATOM   9088  C CB  . ASP C 3 391 ? 171.902 176.309 146.213 1.00 119.47 ? 414 ASP C CB  1 
ATOM   9089  C CG  . ASP C 3 391 ? 171.539 175.417 147.384 1.00 119.47 ? 414 ASP C CG  1 
ATOM   9090  O OD1 . ASP C 3 391 ? 172.434 174.710 147.894 1.00 119.47 ? 414 ASP C OD1 1 
ATOM   9091  O OD2 . ASP C 3 391 ? 170.360 175.424 147.796 1.00 119.47 ? 414 ASP C OD2 1 
ATOM   9092  N N   . TRP C 3 392 ? 174.132 176.621 143.965 1.00 124.06 ? 415 TRP C N   1 
ATOM   9093  C CA  . TRP C 3 392 ? 174.519 177.130 142.657 1.00 124.06 ? 415 TRP C CA  1 
ATOM   9094  C C   . TRP C 3 392 ? 173.291 177.534 141.852 1.00 124.06 ? 415 TRP C C   1 
ATOM   9095  O O   . TRP C 3 392 ? 172.266 176.846 141.865 1.00 124.06 ? 415 TRP C O   1 
ATOM   9096  C CB  . TRP C 3 392 ? 175.320 176.078 141.889 1.00 124.06 ? 415 TRP C CB  1 
ATOM   9097  C CG  . TRP C 3 392 ? 176.705 175.860 142.416 1.00 124.06 ? 415 TRP C CG  1 
ATOM   9098  C CD1 . TRP C 3 392 ? 177.152 174.781 143.120 1.00 124.06 ? 415 TRP C CD1 1 
ATOM   9099  C CD2 . TRP C 3 392 ? 177.828 176.740 142.275 1.00 124.06 ? 415 TRP C CD2 1 
ATOM   9100  N NE1 . TRP C 3 392 ? 178.482 174.934 143.429 1.00 124.06 ? 415 TRP C NE1 1 
ATOM   9101  C CE2 . TRP C 3 392 ? 178.920 176.129 142.922 1.00 124.06 ? 415 TRP C CE2 1 
ATOM   9102  C CE3 . TRP C 3 392 ? 178.014 177.985 141.668 1.00 124.06 ? 415 TRP C CE3 1 
ATOM   9103  C CZ2 . TRP C 3 392 ? 180.181 176.719 142.976 1.00 124.06 ? 415 TRP C CZ2 1 
ATOM   9104  C CZ3 . TRP C 3 392 ? 179.267 178.570 141.723 1.00 124.06 ? 415 TRP C CZ3 1 
ATOM   9105  C CH2 . TRP C 3 392 ? 180.333 177.937 142.374 1.00 124.06 ? 415 TRP C CH2 1 
ATOM   9106  N N   . THR C 3 393 ? 173.401 178.659 141.150 1.00 129.26 ? 416 THR C N   1 
ATOM   9107  C CA  . THR C 3 393 ? 172.348 179.156 140.274 1.00 129.26 ? 416 THR C CA  1 
ATOM   9108  C C   . THR C 3 393 ? 172.847 179.095 138.837 1.00 129.26 ? 416 THR C C   1 
ATOM   9109  O O   . THR C 3 393 ? 173.827 179.762 138.488 1.00 129.26 ? 416 THR C O   1 
ATOM   9110  C CB  . THR C 3 393 ? 171.948 180.584 140.645 1.00 129.26 ? 416 THR C CB  1 
ATOM   9111  O OG1 . THR C 3 393 ? 171.450 180.609 141.988 1.00 129.26 ? 416 THR C OG1 1 
ATOM   9112  C CG2 . THR C 3 393 ? 170.870 181.097 139.702 1.00 129.26 ? 416 THR C CG2 1 
ATOM   9113  N N   . GLN C 3 394 ? 172.176 178.298 138.010 1.00 142.95 ? 417 GLN C N   1 
ATOM   9114  C CA  . GLN C 3 394 ? 172.589 178.059 136.633 1.00 142.95 ? 417 GLN C CA  1 
ATOM   9115  C C   . GLN C 3 394 ? 171.691 178.835 135.680 1.00 142.95 ? 417 GLN C C   1 
ATOM   9116  O O   . GLN C 3 394 ? 170.464 178.824 135.827 1.00 142.95 ? 417 GLN C O   1 
ATOM   9117  C CB  . GLN C 3 394 ? 172.547 176.566 136.303 1.00 142.95 ? 417 GLN C CB  1 
ATOM   9118  C CG  . GLN C 3 394 ? 172.980 176.231 134.886 1.00 142.95 ? 417 GLN C CG  1 
ATOM   9119  C CD  . GLN C 3 394 ? 173.057 174.738 134.640 1.00 142.95 ? 417 GLN C CD  1 
ATOM   9120  O OE1 . GLN C 3 394 ? 172.893 173.936 135.559 1.00 142.95 ? 417 GLN C OE1 1 
ATOM   9121  N NE2 . GLN C 3 394 ? 173.308 174.356 133.393 1.00 142.95 ? 417 GLN C NE2 1 
ATOM   9122  N N   . LYS C 3 395 ? 172.306 179.502 134.705 1.00 154.45 ? 418 LYS C N   1 
ATOM   9123  C CA  . LYS C 3 395 ? 171.576 180.243 133.685 1.00 154.45 ? 418 LYS C CA  1 
ATOM   9124  C C   . LYS C 3 395 ? 172.342 180.149 132.375 1.00 154.45 ? 418 LYS C C   1 
ATOM   9125  O O   . LYS C 3 395 ? 173.527 180.488 132.324 1.00 154.45 ? 418 LYS C O   1 
ATOM   9126  C CB  . LYS C 3 395 ? 171.387 181.709 134.090 1.00 154.45 ? 418 LYS C CB  1 
ATOM   9127  C CG  . LYS C 3 395 ? 170.183 181.957 134.982 1.00 154.45 ? 418 LYS C CG  1 
ATOM   9128  C CD  . LYS C 3 395 ? 168.884 181.677 134.247 1.00 154.45 ? 418 LYS C CD  1 
ATOM   9129  C CE  . LYS C 3 395 ? 167.680 182.009 135.113 1.00 154.45 ? 418 LYS C CE  1 
ATOM   9130  N NZ  . LYS C 3 395 ? 166.397 181.793 134.388 1.00 154.45 ? 418 LYS C NZ  1 
ATOM   9131  N N   . GLU C 3 396 ? 171.666 179.690 131.327 1.00 170.51 ? 419 GLU C N   1 
ATOM   9132  C CA  . GLU C 3 396 ? 172.276 179.496 130.021 1.00 170.51 ? 419 GLU C CA  1 
ATOM   9133  C C   . GLU C 3 396 ? 171.835 180.590 129.058 1.00 170.51 ? 419 GLU C C   1 
ATOM   9134  O O   . GLU C 3 396 ? 170.708 181.089 129.129 1.00 170.51 ? 419 GLU C O   1 
ATOM   9135  C CB  . GLU C 3 396 ? 171.915 178.123 129.445 1.00 170.51 ? 419 GLU C CB  1 
ATOM   9136  C CG  . GLU C 3 396 ? 172.160 176.967 130.400 1.00 170.51 ? 419 GLU C CG  1 
ATOM   9137  C CD  . GLU C 3 396 ? 171.815 175.623 129.788 1.00 170.51 ? 419 GLU C CD  1 
ATOM   9138  O OE1 . GLU C 3 396 ? 172.541 174.643 130.056 1.00 170.51 ? 419 GLU C OE1 1 
ATOM   9139  O OE2 . GLU C 3 396 ? 170.819 175.548 129.039 1.00 170.51 ? 419 GLU C OE2 1 
ATOM   9140  N N   . PHE C 3 397 ? 172.739 180.956 128.153 1.00 186.03 ? 420 PHE C N   1 
ATOM   9141  C CA  . PHE C 3 397 ? 172.455 181.964 127.141 1.00 186.03 ? 420 PHE C CA  1 
ATOM   9142  C C   . PHE C 3 397 ? 173.405 181.758 125.971 1.00 186.03 ? 420 PHE C C   1 
ATOM   9143  O O   . PHE C 3 397 ? 174.477 181.164 126.116 1.00 186.03 ? 420 PHE C O   1 
ATOM   9144  C CB  . PHE C 3 397 ? 172.582 183.384 127.704 1.00 186.03 ? 420 PHE C CB  1 
ATOM   9145  C CG  . PHE C 3 397 ? 173.999 183.812 127.960 1.00 186.03 ? 420 PHE C CG  1 
ATOM   9146  C CD1 . PHE C 3 397 ? 174.681 183.365 129.079 1.00 186.03 ? 420 PHE C CD1 1 
ATOM   9147  C CD2 . PHE C 3 397 ? 174.648 184.668 127.084 1.00 186.03 ? 420 PHE C CD2 1 
ATOM   9148  C CE1 . PHE C 3 397 ? 175.984 183.759 129.319 1.00 186.03 ? 420 PHE C CE1 1 
ATOM   9149  C CE2 . PHE C 3 397 ? 175.951 185.066 127.318 1.00 186.03 ? 420 PHE C CE2 1 
ATOM   9150  C CZ  . PHE C 3 397 ? 176.620 184.610 128.437 1.00 186.03 ? 420 PHE C CZ  1 
ATOM   9151  N N   . SER C 3 398 ? 172.996 182.258 124.808 1.00 196.57 ? 421 SER C N   1 
ATOM   9152  C CA  . SER C 3 398 ? 173.765 182.126 123.578 1.00 196.57 ? 421 SER C CA  1 
ATOM   9153  C C   . SER C 3 398 ? 174.078 183.508 123.023 1.00 196.57 ? 421 SER C C   1 
ATOM   9154  O O   . SER C 3 398 ? 173.180 184.345 122.885 1.00 196.57 ? 421 SER C O   1 
ATOM   9155  C CB  . SER C 3 398 ? 173.004 181.298 122.539 1.00 196.57 ? 421 SER C CB  1 
ATOM   9156  O OG  . SER C 3 398 ? 173.878 180.814 121.534 1.00 196.57 ? 421 SER C OG  1 
ATOM   9157  N N   . THR C 3 399 ? 175.351 183.741 122.708 1.00 199.02 ? 422 THR C N   1 
ATOM   9158  C CA  . THR C 3 399 ? 175.778 185.010 122.144 1.00 199.02 ? 422 THR C CA  1 
ATOM   9159  C C   . THR C 3 399 ? 175.427 185.084 120.657 1.00 199.02 ? 422 THR C C   1 
ATOM   9160  O O   . THR C 3 399 ? 175.451 184.071 119.953 1.00 199.02 ? 422 THR C O   1 
ATOM   9161  C CB  . THR C 3 399 ? 177.282 185.197 122.333 1.00 199.02 ? 422 THR C CB  1 
ATOM   9162  O OG1 . THR C 3 399 ? 177.703 186.416 121.708 1.00 199.02 ? 422 THR C OG1 1 
ATOM   9163  C CG2 . THR C 3 399 ? 178.053 184.029 121.735 1.00 199.02 ? 422 THR C CG2 1 
ATOM   9164  N N   . PRO C 3 400 ? 175.080 186.276 120.158 1.00 201.37 ? 423 PRO C N   1 
ATOM   9165  C CA  . PRO C 3 400 ? 174.754 186.407 118.731 1.00 201.37 ? 423 PRO C CA  1 
ATOM   9166  C C   . PRO C 3 400 ? 175.983 186.333 117.839 1.00 201.37 ? 423 PRO C C   1 
ATOM   9167  O O   . PRO C 3 400 ? 177.101 186.128 118.322 1.00 201.37 ? 423 PRO C O   1 
ATOM   9168  C CB  . PRO C 3 400 ? 174.084 187.785 118.652 1.00 201.37 ? 423 PRO C CB  1 
ATOM   9169  C CG  . PRO C 3 400 ? 174.651 188.540 119.804 1.00 201.37 ? 423 PRO C CG  1 
ATOM   9170  C CD  . PRO C 3 400 ? 174.849 187.529 120.897 1.00 201.37 ? 423 PRO C CD  1 
ATOM   9171  N N   . GLU C 3 401 ? 175.786 186.503 116.536 1.00 213.92 ? 424 GLU C N   1 
ATOM   9172  C CA  . GLU C 3 401 ? 176.860 186.413 115.560 1.00 213.92 ? 424 GLU C CA  1 
ATOM   9173  C C   . GLU C 3 401 ? 177.361 187.803 115.179 1.00 213.92 ? 424 GLU C C   1 
ATOM   9174  O O   . GLU C 3 401 ? 176.759 188.827 115.511 1.00 213.92 ? 424 GLU C O   1 
ATOM   9175  C CB  . GLU C 3 401 ? 176.391 185.652 114.316 1.00 213.92 ? 424 GLU C CB  1 
ATOM   9176  C CG  . GLU C 3 401 ? 176.163 184.167 114.549 1.00 213.92 ? 424 GLU C CG  1 
ATOM   9177  C CD  . GLU C 3 401 ? 175.419 183.504 113.407 1.00 213.92 ? 424 GLU C CD  1 
ATOM   9178  O OE1 . GLU C 3 401 ? 174.318 183.980 113.057 1.00 213.92 ? 424 GLU C OE1 1 
ATOM   9179  O OE2 . GLU C 3 401 ? 175.934 182.507 112.859 1.00 213.92 ? 424 GLU C OE2 1 
ATOM   9180  N N   . THR C 3 402 ? 178.487 187.825 114.468 1.00 219.67 ? 425 THR C N   1 
ATOM   9181  C CA  . THR C 3 402 ? 179.123 189.064 114.046 1.00 219.67 ? 425 THR C CA  1 
ATOM   9182  C C   . THR C 3 402 ? 179.768 188.850 112.683 1.00 219.67 ? 425 THR C C   1 
ATOM   9183  O O   . THR C 3 402 ? 180.154 187.731 112.333 1.00 219.67 ? 425 THR C O   1 
ATOM   9184  C CB  . THR C 3 402 ? 180.174 189.535 115.067 1.00 219.67 ? 425 THR C CB  1 
ATOM   9185  O OG1 . THR C 3 402 ? 179.634 189.435 116.390 1.00 219.67 ? 425 THR C OG1 1 
ATOM   9186  C CG2 . THR C 3 402 ? 180.572 190.982 114.811 1.00 219.67 ? 425 THR C CG2 1 
ATOM   9187  N N   . ALA C 3 403 ? 179.869 189.932 111.913 1.00 226.17 ? 426 ALA C N   1 
ATOM   9188  C CA  . ALA C 3 403 ? 180.490 189.863 110.600 1.00 226.17 ? 426 ALA C CA  1 
ATOM   9189  C C   . ALA C 3 403 ? 181.961 189.464 110.730 1.00 226.17 ? 426 ALA C C   1 
ATOM   9190  O O   . ALA C 3 403 ? 182.605 189.757 111.742 1.00 226.17 ? 426 ALA C O   1 
ATOM   9191  C CB  . ALA C 3 403 ? 180.370 191.207 109.885 1.00 226.17 ? 426 ALA C CB  1 
ATOM   9192  N N   . PRO C 3 404 ? 182.514 188.789 109.724 1.00 227.64 ? 427 PRO C N   1 
ATOM   9193  C CA  . PRO C 3 404 ? 183.918 188.370 109.800 1.00 227.64 ? 427 PRO C CA  1 
ATOM   9194  C C   . PRO C 3 404 ? 184.864 189.561 109.820 1.00 227.64 ? 427 PRO C C   1 
ATOM   9195  O O   . PRO C 3 404 ? 184.514 190.683 109.446 1.00 227.64 ? 427 PRO C O   1 
ATOM   9196  C CB  . PRO C 3 404 ? 184.114 187.530 108.531 1.00 227.64 ? 427 PRO C CB  1 
ATOM   9197  C CG  . PRO C 3 404 ? 182.734 187.157 108.091 1.00 227.64 ? 427 PRO C CG  1 
ATOM   9198  C CD  . PRO C 3 404 ? 181.858 188.296 108.502 1.00 227.64 ? 427 PRO C CD  1 
ATOM   9199  N N   . SER C 3 405 ? 186.092 189.294 110.270 1.00 219.18 ? 428 SER C N   1 
ATOM   9200  C CA  . SER C 3 405 ? 187.112 190.323 110.400 1.00 219.18 ? 428 SER C CA  1 
ATOM   9201  C C   . SER C 3 405 ? 188.375 190.055 109.596 1.00 219.18 ? 428 SER C C   1 
ATOM   9202  O O   . SER C 3 405 ? 189.162 190.987 109.399 1.00 219.18 ? 428 SER C O   1 
ATOM   9203  C CB  . SER C 3 405 ? 187.502 190.508 111.875 1.00 219.18 ? 428 SER C CB  1 
ATOM   9204  O OG  . SER C 3 405 ? 187.679 189.256 112.515 1.00 219.18 ? 428 SER C OG  1 
ATOM   9205  N N   . GLN C 3 406 ? 188.596 188.829 109.134 1.00 219.63 ? 429 GLN C N   1 
ATOM   9206  C CA  . GLN C 3 406 ? 189.788 188.485 108.376 1.00 219.63 ? 429 GLN C CA  1 
ATOM   9207  C C   . GLN C 3 406 ? 189.480 188.445 106.884 1.00 219.63 ? 429 GLN C C   1 
ATOM   9208  O O   . GLN C 3 406 ? 188.352 188.165 106.470 1.00 219.63 ? 429 GLN C O   1 
ATOM   9209  C CB  . GLN C 3 406 ? 190.356 187.138 108.831 1.00 219.63 ? 429 GLN C CB  1 
ATOM   9210  C CG  . GLN C 3 406 ? 189.324 186.030 108.945 1.00 219.63 ? 429 GLN C CG  1 
ATOM   9211  C CD  . GLN C 3 406 ? 189.233 185.184 107.691 1.00 219.63 ? 429 GLN C CD  1 
ATOM   9212  O OE1 . GLN C 3 406 ? 190.145 185.180 106.864 1.00 219.63 ? 429 GLN C OE1 1 
ATOM   9213  N NE2 . GLN C 3 406 ? 188.129 184.461 107.543 1.00 219.63 ? 429 GLN C NE2 1 
ATOM   9214  N N   . ALA C 3 407 ? 190.500 188.732 106.080 1.00 228.17 ? 430 ALA C N   1 
ATOM   9215  C CA  . ALA C 3 407 ? 190.340 188.772 104.634 1.00 228.17 ? 430 ALA C CA  1 
ATOM   9216  C C   . ALA C 3 407 ? 190.441 187.373 104.041 1.00 228.17 ? 430 ALA C C   1 
ATOM   9217  O O   . ALA C 3 407 ? 191.201 186.528 104.525 1.00 228.17 ? 430 ALA C O   1 
ATOM   9218  C CB  . ALA C 3 407 ? 191.393 189.683 104.004 1.00 228.17 ? 430 ALA C CB  1 
ATOM   9219  N N   . LEU C 3 408 ? 189.667 187.134 102.987 1.00 241.55 ? 431 LEU C N   1 
ATOM   9220  C CA  . LEU C 3 408 ? 189.655 185.849 102.303 1.00 241.55 ? 431 LEU C CA  1 
ATOM   9221  C C   . LEU C 3 408 ? 190.670 185.869 101.166 1.00 241.55 ? 431 LEU C C   1 
ATOM   9222  O O   . LEU C 3 408 ? 190.643 186.766 100.317 1.00 241.55 ? 431 LEU C O   1 
ATOM   9223  C CB  . LEU C 3 408 ? 188.248 185.541 101.781 1.00 241.55 ? 431 LEU C CB  1 
ATOM   9224  C CG  . LEU C 3 408 ? 187.927 184.226 101.061 1.00 241.55 ? 431 LEU C CG  1 
ATOM   9225  C CD1 . LEU C 3 408 ? 186.446 183.928 101.184 1.00 241.55 ? 431 LEU C CD1 1 
ATOM   9226  C CD2 . LEU C 3 408 ? 188.298 184.289 99.592  1.00 241.55 ? 431 LEU C CD2 1 
ATOM   9227  N N   . ASP C 3 409 ? 191.560 184.879 101.154 1.00 251.44 ? 432 ASP C N   1 
ATOM   9228  C CA  . ASP C 3 409 ? 192.582 184.802 100.119 1.00 251.44 ? 432 ASP C CA  1 
ATOM   9229  C C   . ASP C 3 409 ? 191.968 184.340 98.803  1.00 251.44 ? 432 ASP C C   1 
ATOM   9230  O O   . ASP C 3 409 ? 191.218 183.360 98.764  1.00 251.44 ? 432 ASP C O   1 
ATOM   9231  C CB  . ASP C 3 409 ? 193.702 183.856 100.551 1.00 251.44 ? 432 ASP C CB  1 
ATOM   9232  C CG  . ASP C 3 409 ? 193.214 182.438 100.778 1.00 251.44 ? 432 ASP C CG  1 
ATOM   9233  O OD1 . ASP C 3 409 ? 193.366 181.602 99.863  1.00 251.44 ? 432 ASP C OD1 1 
ATOM   9234  O OD2 . ASP C 3 409 ? 192.677 182.160 101.871 1.00 251.44 ? 432 ASP C OD2 1 
ATOM   9235  N N   . VAL C 3 410 ? 192.290 185.047 97.722  1.00 255.92 ? 433 VAL C N   1 
ATOM   9236  C CA  . VAL C 3 410 ? 191.708 184.779 96.415  1.00 255.92 ? 433 VAL C CA  1 
ATOM   9237  C C   . VAL C 3 410 ? 192.820 184.464 95.423  1.00 255.92 ? 433 VAL C C   1 
ATOM   9238  O O   . VAL C 3 410 ? 193.984 184.830 95.610  1.00 255.92 ? 433 VAL C O   1 
ATOM   9239  C CB  . VAL C 3 410 ? 190.849 185.957 95.909  1.00 255.92 ? 433 VAL C CB  1 
ATOM   9240  C CG1 . VAL C 3 410 ? 189.775 186.308 96.925  1.00 255.92 ? 433 VAL C CG1 1 
ATOM   9241  C CG2 . VAL C 3 410 ? 191.724 187.165 95.617  1.00 255.92 ? 433 VAL C CG2 1 
ATOM   9242  N N   . TRP C 3 411 ? 192.441 183.766 94.355  1.00 262.91 ? 434 TRP C N   1 
ATOM   9243  C CA  . TRP C 3 411 ? 193.357 183.445 93.269  1.00 262.91 ? 434 TRP C CA  1 
ATOM   9244  C C   . TRP C 3 411 ? 192.537 183.183 92.015  1.00 262.91 ? 434 TRP C C   1 
ATOM   9245  O O   . TRP C 3 411 ? 191.348 182.861 92.085  1.00 262.91 ? 434 TRP C O   1 
ATOM   9246  C CB  . TRP C 3 411 ? 194.240 182.239 93.610  1.00 262.91 ? 434 TRP C CB  1 
ATOM   9247  C CG  . TRP C 3 411 ? 195.398 182.054 92.673  1.00 262.91 ? 434 TRP C CG  1 
ATOM   9248  C CD1 . TRP C 3 411 ? 195.660 180.958 91.903  1.00 262.91 ? 434 TRP C CD1 1 
ATOM   9249  C CD2 . TRP C 3 411 ? 196.449 182.992 92.406  1.00 262.91 ? 434 TRP C CD2 1 
ATOM   9250  N NE1 . TRP C 3 411 ? 196.808 181.155 91.174  1.00 262.91 ? 434 TRP C NE1 1 
ATOM   9251  C CE2 . TRP C 3 411 ? 197.311 182.396 91.464  1.00 262.91 ? 434 TRP C CE2 1 
ATOM   9252  C CE3 . TRP C 3 411 ? 196.744 184.278 92.871  1.00 262.91 ? 434 TRP C CE3 1 
ATOM   9253  C CZ2 . TRP C 3 411 ? 198.448 183.040 90.980  1.00 262.91 ? 434 TRP C CZ2 1 
ATOM   9254  C CZ3 . TRP C 3 411 ? 197.872 184.916 92.388  1.00 262.91 ? 434 TRP C CZ3 1 
ATOM   9255  C CH2 . TRP C 3 411 ? 198.710 184.296 91.453  1.00 262.91 ? 434 TRP C CH2 1 
ATOM   9256  N N   . ARG C 3 412 ? 193.189 183.326 90.864  1.00 266.76 ? 435 ARG C N   1 
ATOM   9257  C CA  . ARG C 3 412 ? 192.524 183.232 89.574  1.00 266.76 ? 435 ARG C CA  1 
ATOM   9258  C C   . ARG C 3 412 ? 193.324 182.339 88.635  1.00 266.76 ? 435 ARG C C   1 
ATOM   9259  O O   . ARG C 3 412 ? 194.465 181.961 88.914  1.00 266.76 ? 435 ARG C O   1 
ATOM   9260  C CB  . ARG C 3 412 ? 192.335 184.619 88.946  1.00 266.76 ? 435 ARG C CB  1 
ATOM   9261  C CG  . ARG C 3 412 ? 193.638 185.362 88.706  1.00 266.76 ? 435 ARG C CG  1 
ATOM   9262  C CD  . ARG C 3 412 ? 193.424 186.589 87.839  1.00 266.76 ? 435 ARG C CD  1 
ATOM   9263  N NE  . ARG C 3 412 ? 194.655 187.352 87.659  1.00 266.76 ? 435 ARG C NE  1 
ATOM   9264  C CZ  . ARG C 3 412 ? 195.022 188.369 88.433  1.00 266.76 ? 435 ARG C CZ  1 
ATOM   9265  N NH1 . ARG C 3 412 ? 194.251 188.747 89.443  1.00 266.76 ? 435 ARG C NH1 1 
ATOM   9266  N NH2 . ARG C 3 412 ? 196.159 189.008 88.197  1.00 266.76 ? 435 ARG C NH2 1 
ATOM   9267  N N   . GLN C 3 413 ? 192.700 182.006 87.507  1.00 272.55 ? 436 GLN C N   1 
ATOM   9268  C CA  . GLN C 3 413 ? 193.348 181.225 86.455  1.00 272.55 ? 436 GLN C CA  1 
ATOM   9269  C C   . GLN C 3 413 ? 192.738 181.655 85.129  1.00 272.55 ? 436 GLN C C   1 
ATOM   9270  O O   . GLN C 3 413 ? 191.552 181.412 84.886  1.00 272.55 ? 436 GLN C O   1 
ATOM   9271  C CB  . GLN C 3 413 ? 193.170 179.727 86.687  1.00 272.55 ? 436 GLN C CB  1 
ATOM   9272  C CG  . GLN C 3 413 ? 193.601 178.861 85.513  1.00 272.55 ? 436 GLN C CG  1 
ATOM   9273  C CD  . GLN C 3 413 ? 195.093 178.934 85.249  1.00 272.55 ? 436 GLN C CD  1 
ATOM   9274  O OE1 . GLN C 3 413 ? 195.886 179.167 86.161  1.00 272.55 ? 436 GLN C OE1 1 
ATOM   9275  N NE2 . GLN C 3 413 ? 195.482 178.733 83.996  1.00 272.55 ? 436 GLN C NE2 1 
ATOM   9276  N N   . VAL C 3 414 ? 193.540 182.290 84.280  1.00 277.37 ? 437 VAL C N   1 
ATOM   9277  C CA  . VAL C 3 414 ? 193.056 182.850 83.027  1.00 277.37 ? 437 VAL C CA  1 
ATOM   9278  C C   . VAL C 3 414 ? 193.606 182.039 81.860  1.00 277.37 ? 437 VAL C C   1 
ATOM   9279  O O   . VAL C 3 414 ? 194.645 181.377 81.955  1.00 277.37 ? 437 VAL C O   1 
ATOM   9280  C CB  . VAL C 3 414 ? 193.430 184.340 82.880  1.00 277.37 ? 437 VAL C CB  1 
ATOM   9281  C CG1 . VAL C 3 414 ? 192.932 185.131 84.078  1.00 277.37 ? 437 VAL C CG1 1 
ATOM   9282  C CG2 . VAL C 3 414 ? 194.935 184.499 82.718  1.00 277.37 ? 437 VAL C CG2 1 
ATOM   9283  N N   . TRP C 3 415 ? 192.885 182.094 80.745  1.00 281.66 ? 438 TRP C N   1 
ATOM   9284  C CA  . TRP C 3 415 ? 193.302 181.451 79.506  1.00 281.66 ? 438 TRP C CA  1 
ATOM   9285  C C   . TRP C 3 415 ? 192.570 182.126 78.353  1.00 281.66 ? 438 TRP C C   1 
ATOM   9286  O O   . TRP C 3 415 ? 191.724 183.001 78.556  1.00 281.66 ? 438 TRP C O   1 
ATOM   9287  C CB  . TRP C 3 415 ? 193.038 179.941 79.540  1.00 281.66 ? 438 TRP C CB  1 
ATOM   9288  C CG  . TRP C 3 415 ? 191.585 179.562 79.613  1.00 281.66 ? 438 TRP C CG  1 
ATOM   9289  C CD1 . TRP C 3 415 ? 190.673 179.600 78.597  1.00 281.66 ? 438 TRP C CD1 1 
ATOM   9290  C CD2 . TRP C 3 415 ? 190.882 179.073 80.762  1.00 281.66 ? 438 TRP C CD2 1 
ATOM   9291  N NE1 . TRP C 3 415 ? 189.447 179.174 79.044  1.00 281.66 ? 438 TRP C NE1 1 
ATOM   9292  C CE2 . TRP C 3 415 ? 189.548 178.844 80.370  1.00 281.66 ? 438 TRP C CE2 1 
ATOM   9293  C CE3 . TRP C 3 415 ? 191.250 178.811 82.085  1.00 281.66 ? 438 TRP C CE3 1 
ATOM   9294  C CZ2 . TRP C 3 415 ? 188.582 178.365 81.252  1.00 281.66 ? 438 TRP C CZ2 1 
ATOM   9295  C CZ3 . TRP C 3 415 ? 190.290 178.336 82.960  1.00 281.66 ? 438 TRP C CZ3 1 
ATOM   9296  C CH2 . TRP C 3 415 ? 188.972 178.117 82.539  1.00 281.66 ? 438 TRP C CH2 1 
ATOM   9297  N N   . SER C 3 416 ? 192.903 181.711 77.135  1.00 285.55 ? 439 SER C N   1 
ATOM   9298  C CA  . SER C 3 416 ? 192.281 182.238 75.929  1.00 285.55 ? 439 SER C CA  1 
ATOM   9299  C C   . SER C 3 416 ? 191.260 181.237 75.404  1.00 285.55 ? 439 SER C C   1 
ATOM   9300  O O   . SER C 3 416 ? 191.595 180.075 75.152  1.00 285.55 ? 439 SER C O   1 
ATOM   9301  C CB  . SER C 3 416 ? 193.331 182.536 74.857  1.00 285.55 ? 439 SER C CB  1 
ATOM   9302  O OG  . SER C 3 416 ? 192.747 183.175 73.735  1.00 285.55 ? 439 SER C OG  1 
ATOM   9303  N N   . GLU C 3 417 ? 190.019 181.691 75.242  1.00 284.23 ? 440 GLU C N   1 
ATOM   9304  C CA  . GLU C 3 417 ? 188.945 180.835 74.751  1.00 284.23 ? 440 GLU C CA  1 
ATOM   9305  C C   . GLU C 3 417 ? 187.911 181.707 74.058  1.00 284.23 ? 440 GLU C C   1 
ATOM   9306  O O   . GLU C 3 417 ? 187.428 182.679 74.648  1.00 284.23 ? 440 GLU C O   1 
ATOM   9307  C CB  . GLU C 3 417 ? 188.307 180.041 75.894  1.00 284.23 ? 440 GLU C CB  1 
ATOM   9308  C CG  . GLU C 3 417 ? 187.305 178.993 75.440  1.00 284.23 ? 440 GLU C CG  1 
ATOM   9309  C CD  . GLU C 3 417 ? 186.776 178.157 76.588  1.00 284.23 ? 440 GLU C CD  1 
ATOM   9310  O OE1 . GLU C 3 417 ? 187.308 178.282 77.711  1.00 284.23 ? 440 GLU C OE1 1 
ATOM   9311  O OE2 . GLU C 3 417 ? 185.827 177.375 76.368  1.00 284.23 ? 440 GLU C OE2 1 
ATOM   9312  N N   . ASN C 3 418 ? 187.580 181.357 72.813  1.00 281.62 ? 441 ASN C N   1 
ATOM   9313  C CA  . ASN C 3 418 ? 186.630 182.113 71.993  1.00 281.62 ? 441 ASN C CA  1 
ATOM   9314  C C   . ASN C 3 418 ? 187.051 183.571 71.833  1.00 281.62 ? 441 ASN C C   1 
ATOM   9315  O O   . ASN C 3 418 ? 186.209 184.459 71.679  1.00 281.62 ? 441 ASN C O   1 
ATOM   9316  C CB  . ASN C 3 418 ? 185.208 182.029 72.559  1.00 281.62 ? 441 ASN C CB  1 
ATOM   9317  C CG  . ASN C 3 418 ? 184.896 180.671 73.156  1.00 281.62 ? 441 ASN C CG  1 
ATOM   9318  O OD1 . ASN C 3 418 ? 184.913 179.655 72.461  1.00 281.62 ? 441 ASN C OD1 1 
ATOM   9319  N ND2 . ASN C 3 418 ? 184.601 180.648 74.451  1.00 281.62 ? 441 ASN C ND2 1 
ATOM   9320  N N   . GLY C 3 419 ? 188.359 183.830 71.868  1.00 282.28 ? 442 GLY C N   1 
ATOM   9321  C CA  . GLY C 3 419 ? 188.881 185.174 71.746  1.00 282.28 ? 442 GLY C CA  1 
ATOM   9322  C C   . GLY C 3 419 ? 188.726 186.044 72.972  1.00 282.28 ? 442 GLY C C   1 
ATOM   9323  O O   . GLY C 3 419 ? 189.264 187.159 72.990  1.00 282.28 ? 442 GLY C O   1 
ATOM   9324  N N   . ARG C 3 420 ? 188.014 185.583 73.996  1.00 282.53 ? 443 ARG C N   1 
ATOM   9325  C CA  . ARG C 3 420 ? 187.796 186.346 75.214  1.00 282.53 ? 443 ARG C CA  1 
ATOM   9326  C C   . ARG C 3 420 ? 188.649 185.788 76.346  1.00 282.53 ? 443 ARG C C   1 
ATOM   9327  O O   . ARG C 3 420 ? 189.037 184.616 76.336  1.00 282.53 ? 443 ARG C O   1 
ATOM   9328  C CB  . ARG C 3 420 ? 186.319 186.326 75.620  1.00 282.53 ? 443 ARG C CB  1 
ATOM   9329  C CG  . ARG C 3 420 ? 185.377 186.879 74.563  1.00 282.53 ? 443 ARG C CG  1 
ATOM   9330  C CD  . ARG C 3 420 ? 183.960 187.000 75.097  1.00 282.53 ? 443 ARG C CD  1 
ATOM   9331  N NE  . ARG C 3 420 ? 183.879 187.917 76.230  1.00 282.53 ? 443 ARG C NE  1 
ATOM   9332  C CZ  . ARG C 3 420 ? 182.755 188.214 76.873  1.00 282.53 ? 443 ARG C CZ  1 
ATOM   9333  N NH1 . ARG C 3 420 ? 181.608 187.665 76.494  1.00 282.53 ? 443 ARG C NH1 1 
ATOM   9334  N NH2 . ARG C 3 420 ? 182.775 189.059 77.894  1.00 282.53 ? 443 ARG C NH2 1 
ATOM   9335  N N   . ARG C 3 421 ? 188.937 186.643 77.324  1.00 280.33 ? 444 ARG C N   1 
ATOM   9336  C CA  . ARG C 3 421 ? 189.741 186.261 78.482  1.00 280.33 ? 444 ARG C CA  1 
ATOM   9337  C C   . ARG C 3 421 ? 188.827 185.615 79.515  1.00 280.33 ? 444 ARG C C   1 
ATOM   9338  O O   . ARG C 3 421 ? 188.118 186.303 80.254  1.00 280.33 ? 444 ARG C O   1 
ATOM   9339  C CB  . ARG C 3 421 ? 190.461 187.475 79.058  1.00 280.33 ? 444 ARG C CB  1 
ATOM   9340  C CG  . ARG C 3 421 ? 191.309 187.174 80.282  1.00 280.33 ? 444 ARG C CG  1 
ATOM   9341  C CD  . ARG C 3 421 ? 191.903 188.446 80.862  1.00 280.33 ? 444 ARG C CD  1 
ATOM   9342  N NE  . ARG C 3 421 ? 192.702 189.172 79.880  1.00 280.33 ? 444 ARG C NE  1 
ATOM   9343  C CZ  . ARG C 3 421 ? 193.262 190.357 80.100  1.00 280.33 ? 444 ARG C CZ  1 
ATOM   9344  N NH1 . ARG C 3 421 ? 193.109 190.956 81.273  1.00 280.33 ? 444 ARG C NH1 1 
ATOM   9345  N NH2 . ARG C 3 421 ? 193.973 190.944 79.148  1.00 280.33 ? 444 ARG C NH2 1 
ATOM   9346  N N   . ILE C 3 422 ? 188.840 184.288 79.569  1.00 280.60 ? 445 ILE C N   1 
ATOM   9347  C CA  . ILE C 3 422 ? 188.023 183.537 80.515  1.00 280.60 ? 445 ILE C CA  1 
ATOM   9348  C C   . ILE C 3 422 ? 188.809 183.382 81.810  1.00 280.60 ? 445 ILE C C   1 
ATOM   9349  O O   . ILE C 3 422 ? 189.914 182.827 81.814  1.00 280.60 ? 445 ILE C O   1 
ATOM   9350  C CB  . ILE C 3 422 ? 187.622 182.170 79.943  1.00 280.60 ? 445 ILE C CB  1 
ATOM   9351  C CG1 . ILE C 3 422 ? 186.941 182.340 78.584  1.00 280.60 ? 445 ILE C CG1 1 
ATOM   9352  C CG2 . ILE C 3 422 ? 186.709 181.434 80.912  1.00 280.60 ? 445 ILE C CG2 1 
ATOM   9353  C CD1 . ILE C 3 422 ? 185.682 183.177 78.632  1.00 280.60 ? 445 ILE C CD1 1 
ATOM   9354  N N   . VAL C 3 423 ? 188.241 183.871 82.909  1.00 273.66 ? 446 VAL C N   1 
ATOM   9355  C CA  . VAL C 3 423 ? 188.881 183.827 84.218  1.00 273.66 ? 446 VAL C CA  1 
ATOM   9356  C C   . VAL C 3 423 ? 188.046 182.954 85.145  1.00 273.66 ? 446 VAL C C   1 
ATOM   9357  O O   . VAL C 3 423 ? 186.811 183.011 85.128  1.00 273.66 ? 446 VAL C O   1 
ATOM   9358  C CB  . VAL C 3 423 ? 189.076 185.243 84.805  1.00 273.66 ? 446 VAL C CB  1 
ATOM   9359  C CG1 . VAL C 3 423 ? 187.737 185.938 85.025  1.00 273.66 ? 446 VAL C CG1 1 
ATOM   9360  C CG2 . VAL C 3 423 ? 189.871 185.182 86.101  1.00 273.66 ? 446 VAL C CG2 1 
ATOM   9361  N N   . THR C 3 424 ? 188.726 182.125 85.934  1.00 268.18 ? 447 THR C N   1 
ATOM   9362  C CA  . THR C 3 424 ? 188.088 181.254 86.913  1.00 268.18 ? 447 THR C CA  1 
ATOM   9363  C C   . THR C 3 424 ? 188.634 181.597 88.290  1.00 268.18 ? 447 THR C C   1 
ATOM   9364  O O   . THR C 3 424 ? 189.838 181.465 88.535  1.00 268.18 ? 447 THR C O   1 
ATOM   9365  C CB  . THR C 3 424 ? 188.334 179.779 86.588  1.00 268.18 ? 447 THR C CB  1 
ATOM   9366  O OG1 . THR C 3 424 ? 188.155 179.562 85.183  1.00 268.18 ? 447 THR C OG1 1 
ATOM   9367  C CG2 . THR C 3 424 ? 187.365 178.895 87.358  1.00 268.18 ? 447 THR C CG2 1 
ATOM   9368  N N   . LEU C 3 425 ? 187.752 182.036 89.183  1.00 262.77 ? 448 LEU C N   1 
ATOM   9369  C CA  . LEU C 3 425 ? 188.134 182.454 90.524  1.00 262.77 ? 448 LEU C CA  1 
ATOM   9370  C C   . LEU C 3 425 ? 187.954 181.297 91.497  1.00 262.77 ? 448 LEU C C   1 
ATOM   9371  O O   . LEU C 3 425 ? 186.889 180.673 91.539  1.00 262.77 ? 448 LEU C O   1 
ATOM   9372  C CB  . LEU C 3 425 ? 187.307 183.660 90.977  1.00 262.77 ? 448 LEU C CB  1 
ATOM   9373  C CG  . LEU C 3 425 ? 187.210 184.839 90.005  1.00 262.77 ? 448 LEU C CG  1 
ATOM   9374  C CD1 . LEU C 3 425 ? 185.959 184.744 89.143  1.00 262.77 ? 448 LEU C CD1 1 
ATOM   9375  C CD2 . LEU C 3 425 ? 187.243 186.159 90.758  1.00 262.77 ? 448 LEU C CD2 1 
ATOM   9376  N N   . PHE C 3 426 ? 188.998 181.014 92.272  1.00 260.98 ? 449 PHE C N   1 
ATOM   9377  C CA  . PHE C 3 426 ? 188.973 179.969 93.283  1.00 260.98 ? 449 PHE C CA  1 
ATOM   9378  C C   . PHE C 3 426 ? 189.174 180.586 94.660  1.00 260.98 ? 449 PHE C C   1 
ATOM   9379  O O   . PHE C 3 426 ? 189.903 181.570 94.817  1.00 260.98 ? 449 PHE C O   1 
ATOM   9380  C CB  . PHE C 3 426 ? 190.056 178.912 93.025  1.00 260.98 ? 449 PHE C CB  1 
ATOM   9381  C CG  . PHE C 3 426 ? 189.904 178.193 91.714  1.00 260.98 ? 449 PHE C CG  1 
ATOM   9382  C CD1 . PHE C 3 426 ? 189.119 177.056 91.620  1.00 260.98 ? 449 PHE C CD1 1 
ATOM   9383  C CD2 . PHE C 3 426 ? 190.549 178.653 90.578  1.00 260.98 ? 449 PHE C CD2 1 
ATOM   9384  C CE1 . PHE C 3 426 ? 188.978 176.391 90.416  1.00 260.98 ? 449 PHE C CE1 1 
ATOM   9385  C CE2 . PHE C 3 426 ? 190.412 177.993 89.371  1.00 260.98 ? 449 PHE C CE2 1 
ATOM   9386  C CZ  . PHE C 3 426 ? 189.626 176.861 89.290  1.00 260.98 ? 449 PHE C CZ  1 
ATOM   9387  N N   . TRP C 3 427 ? 188.519 179.999 95.659  1.00 256.48 ? 450 TRP C N   1 
ATOM   9388  C CA  . TRP C 3 427 ? 188.632 180.479 97.028  1.00 256.48 ? 450 TRP C CA  1 
ATOM   9389  C C   . TRP C 3 427 ? 188.450 179.313 97.986  1.00 256.48 ? 450 TRP C C   1 
ATOM   9390  O O   . TRP C 3 427 ? 187.664 178.398 97.722  1.00 256.48 ? 450 TRP C O   1 
ATOM   9391  C CB  . TRP C 3 427 ? 187.606 181.579 97.325  1.00 256.48 ? 450 TRP C CB  1 
ATOM   9392  C CG  . TRP C 3 427 ? 186.190 181.186 97.041  1.00 256.48 ? 450 TRP C CG  1 
ATOM   9393  C CD1 . TRP C 3 427 ? 185.322 180.573 97.896  1.00 256.48 ? 450 TRP C CD1 1 
ATOM   9394  C CD2 . TRP C 3 427 ? 185.473 181.389 95.817  1.00 256.48 ? 450 TRP C CD2 1 
ATOM   9395  N NE1 . TRP C 3 427 ? 184.110 180.378 97.280  1.00 256.48 ? 450 TRP C NE1 1 
ATOM   9396  C CE2 . TRP C 3 427 ? 184.176 180.871 96.004  1.00 256.48 ? 450 TRP C CE2 1 
ATOM   9397  C CE3 . TRP C 3 427 ? 185.801 181.957 94.583  1.00 256.48 ? 450 TRP C CE3 1 
ATOM   9398  C CZ2 . TRP C 3 427 ? 183.209 180.902 95.002  1.00 256.48 ? 450 TRP C CZ2 1 
ATOM   9399  C CZ3 . TRP C 3 427 ? 184.839 181.987 93.590  1.00 256.48 ? 450 TRP C CZ3 1 
ATOM   9400  C CH2 . TRP C 3 427 ? 183.559 181.463 93.805  1.00 256.48 ? 450 TRP C CH2 1 
ATOM   9401  N N   . LYS C 3 428 ? 189.187 179.357 99.107  1.00 242.31 ? 451 LYS C N   1 
ATOM   9402  C CA  . LYS C 3 428 ? 189.186 178.345 100.151 1.00 242.31 ? 451 LYS C CA  1 
ATOM   9403  C C   . LYS C 3 428 ? 188.137 178.666 101.211 1.00 242.31 ? 451 LYS C C   1 
ATOM   9404  O O   . LYS C 3 428 ? 187.859 179.838 101.486 1.00 242.31 ? 451 LYS C O   1 
ATOM   9405  C CB  . LYS C 3 428 ? 190.561 178.257 100.806 1.00 242.31 ? 451 LYS C CB  1 
ATOM   9406  C CG  . LYS C 3 428 ? 191.700 178.026 99.828  1.00 242.31 ? 451 LYS C CG  1 
ATOM   9407  C CD  . LYS C 3 428 ? 193.046 178.071 100.531 1.00 242.31 ? 451 LYS C CD  1 
ATOM   9408  C CE  . LYS C 3 428 ? 194.186 177.875 99.547  1.00 242.31 ? 451 LYS C CE  1 
ATOM   9409  N NZ  . LYS C 3 428 ? 195.515 177.953 100.215 1.00 242.31 ? 451 LYS C NZ  1 
ATOM   9410  N N   . PRO C 3 429 ? 187.539 177.643 101.820 1.00 223.66 ? 452 PRO C N   1 
ATOM   9411  C CA  . PRO C 3 429 ? 186.528 177.896 102.853 1.00 223.66 ? 452 PRO C CA  1 
ATOM   9412  C C   . PRO C 3 429 ? 187.156 178.468 104.114 1.00 223.66 ? 452 PRO C C   1 
ATOM   9413  O O   . PRO C 3 429 ? 188.274 178.112 104.493 1.00 223.66 ? 452 PRO C O   1 
ATOM   9414  C CB  . PRO C 3 429 ? 185.922 176.511 103.105 1.00 223.66 ? 452 PRO C CB  1 
ATOM   9415  C CG  . PRO C 3 429 ? 187.000 175.557 102.714 1.00 223.66 ? 452 PRO C CG  1 
ATOM   9416  C CD  . PRO C 3 429 ? 187.728 176.203 101.570 1.00 223.66 ? 452 PRO C CD  1 
ATOM   9417  N N   . LEU C 3 430 ? 186.419 179.364 104.764 1.00 207.48 ? 453 LEU C N   1 
ATOM   9418  C CA  . LEU C 3 430 ? 186.896 180.000 105.980 1.00 207.48 ? 453 LEU C CA  1 
ATOM   9419  C C   . LEU C 3 430 ? 186.770 179.053 107.169 1.00 207.48 ? 453 LEU C C   1 
ATOM   9420  O O   . LEU C 3 430 ? 185.976 178.108 107.168 1.00 207.48 ? 453 LEU C O   1 
ATOM   9421  C CB  . LEU C 3 430 ? 186.121 181.290 106.253 1.00 207.48 ? 453 LEU C CB  1 
ATOM   9422  C CG  . LEU C 3 430 ? 186.011 182.291 105.101 1.00 207.48 ? 453 LEU C CG  1 
ATOM   9423  C CD1 . LEU C 3 430 ? 185.460 183.617 105.598 1.00 207.48 ? 453 LEU C CD1 1 
ATOM   9424  C CD2 . LEU C 3 430 ? 187.365 182.492 104.436 1.00 207.48 ? 453 LEU C CD2 1 
ATOM   9425  N N   . LEU C 3 431 ? 187.572 179.321 108.195 1.00 190.21 ? 454 LEU C N   1 
ATOM   9426  C CA  . LEU C 3 431 ? 187.567 178.510 109.401 1.00 190.21 ? 454 LEU C CA  1 
ATOM   9427  C C   . LEU C 3 431 ? 186.363 178.866 110.270 1.00 190.21 ? 454 LEU C C   1 
ATOM   9428  O O   . LEU C 3 431 ? 185.537 179.716 109.924 1.00 190.21 ? 454 LEU C O   1 
ATOM   9429  C CB  . LEU C 3 431 ? 188.873 178.687 110.176 1.00 190.21 ? 454 LEU C CB  1 
ATOM   9430  C CG  . LEU C 3 431 ? 190.180 178.084 109.642 1.00 190.21 ? 454 LEU C CG  1 
ATOM   9431  C CD1 . LEU C 3 431 ? 190.643 178.731 108.340 1.00 190.21 ? 454 LEU C CD1 1 
ATOM   9432  C CD2 . LEU C 3 431 ? 191.271 178.172 110.700 1.00 190.21 ? 454 LEU C CD2 1 
ATOM   9433  N N   . LYS C 3 432 ? 186.261 178.203 111.424 1.00 181.09 ? 455 LYS C N   1 
ATOM   9434  C CA  . LYS C 3 432 ? 185.152 178.462 112.336 1.00 181.09 ? 455 LYS C CA  1 
ATOM   9435  C C   . LYS C 3 432 ? 185.325 179.802 113.041 1.00 181.09 ? 455 LYS C C   1 
ATOM   9436  O O   . LYS C 3 432 ? 184.473 180.692 112.933 1.00 181.09 ? 455 LYS C O   1 
ATOM   9437  C CB  . LYS C 3 432 ? 185.035 177.327 113.354 1.00 181.09 ? 455 LYS C CB  1 
ATOM   9438  C CG  . LYS C 3 432 ? 183.815 177.427 114.254 1.00 181.09 ? 455 LYS C CG  1 
ATOM   9439  C CD  . LYS C 3 432 ? 184.027 176.676 115.558 1.00 181.09 ? 455 LYS C CD  1 
ATOM   9440  C CE  . LYS C 3 432 ? 185.129 177.316 116.386 1.00 181.09 ? 455 LYS C CE  1 
ATOM   9441  N NZ  . LYS C 3 432 ? 184.866 178.760 116.637 1.00 181.09 ? 455 LYS C NZ  1 
ATOM   9442  N N   . SER C 3 433 ? 186.430 179.965 113.771 1.00 183.69 ? 456 SER C N   1 
ATOM   9443  C CA  . SER C 3 433 ? 186.680 181.204 114.496 1.00 183.69 ? 456 SER C CA  1 
ATOM   9444  C C   . SER C 3 433 ? 187.051 182.362 113.581 1.00 183.69 ? 456 SER C C   1 
ATOM   9445  O O   . SER C 3 433 ? 187.082 183.507 114.044 1.00 183.69 ? 456 SER C O   1 
ATOM   9446  C CB  . SER C 3 433 ? 187.785 180.991 115.532 1.00 183.69 ? 456 SER C CB  1 
ATOM   9447  O OG  . SER C 3 433 ? 187.271 180.399 116.712 1.00 183.69 ? 456 SER C OG  1 
ATOM   9448  N N   . GLN C 3 434 ? 187.333 182.099 112.306 1.00 190.60 ? 457 GLN C N   1 
ATOM   9449  C CA  . GLN C 3 434 ? 187.669 183.157 111.364 1.00 190.60 ? 457 GLN C CA  1 
ATOM   9450  C C   . GLN C 3 434 ? 186.454 183.713 110.635 1.00 190.60 ? 457 GLN C C   1 
ATOM   9451  O O   . GLN C 3 434 ? 186.532 184.816 110.083 1.00 190.60 ? 457 GLN C O   1 
ATOM   9452  C CB  . GLN C 3 434 ? 188.688 182.648 110.340 1.00 190.60 ? 457 GLN C CB  1 
ATOM   9453  C CG  . GLN C 3 434 ? 190.139 182.842 110.756 1.00 190.60 ? 457 GLN C CG  1 
ATOM   9454  C CD  . GLN C 3 434 ? 190.549 181.943 111.909 1.00 190.60 ? 457 GLN C CD  1 
ATOM   9455  O OE1 . GLN C 3 434 ? 189.842 180.999 112.260 1.00 190.60 ? 457 GLN C OE1 1 
ATOM   9456  N NE2 . GLN C 3 434 ? 191.699 182.235 112.504 1.00 190.60 ? 457 GLN C NE2 1 
ATOM   9457  N N   . ALA C 3 435 ? 185.341 182.982 110.620 1.00 201.53 ? 458 ALA C N   1 
ATOM   9458  C CA  . ALA C 3 435 ? 184.121 183.443 109.970 1.00 201.53 ? 458 ALA C CA  1 
ATOM   9459  C C   . ALA C 3 435 ? 183.150 184.120 110.924 1.00 201.53 ? 458 ALA C C   1 
ATOM   9460  O O   . ALA C 3 435 ? 182.357 184.960 110.485 1.00 201.53 ? 458 ALA C O   1 
ATOM   9461  C CB  . ALA C 3 435 ? 183.412 182.273 109.279 1.00 201.53 ? 458 ALA C CB  1 
ATOM   9462  N N   . ASN C 3 436 ? 183.191 183.769 112.211 1.00 201.72 ? 459 ASN C N   1 
ATOM   9463  C CA  . ASN C 3 436 ? 182.319 184.354 113.231 1.00 201.72 ? 459 ASN C CA  1 
ATOM   9464  C C   . ASN C 3 436 ? 180.842 184.152 112.903 1.00 201.72 ? 459 ASN C C   1 
ATOM   9465  O O   . ASN C 3 436 ? 179.998 184.981 113.252 1.00 201.72 ? 459 ASN C O   1 
ATOM   9466  C CB  . ASN C 3 436 ? 182.621 185.842 113.436 1.00 201.72 ? 459 ASN C CB  1 
ATOM   9467  C CG  . ASN C 3 436 ? 184.077 186.101 113.771 1.00 201.72 ? 459 ASN C CG  1 
ATOM   9468  O OD1 . ASN C 3 436 ? 184.740 185.269 114.390 1.00 201.72 ? 459 ASN C OD1 1 
ATOM   9469  N ND2 . ASN C 3 436 ? 184.582 187.258 113.361 1.00 201.72 ? 459 ASN C ND2 1 
ATOM   9470  N N   . GLY C 3 437 ? 180.519 183.058 112.237 1.00 207.92 ? 460 GLY C N   1 
ATOM   9471  C CA  . GLY C 3 437 ? 179.146 182.771 111.873 1.00 207.92 ? 460 GLY C CA  1 
ATOM   9472  C C   . GLY C 3 437 ? 179.093 181.911 110.627 1.00 207.92 ? 460 GLY C C   1 
ATOM   9473  O O   . GLY C 3 437 ? 180.111 181.547 110.046 1.00 207.92 ? 460 GLY C O   1 
ATOM   9474  N N   . LYS C 3 438 ? 177.864 181.591 110.230 1.00 223.79 ? 461 LYS C N   1 
ATOM   9475  C CA  . LYS C 3 438 ? 177.633 180.769 109.051 1.00 223.79 ? 461 LYS C CA  1 
ATOM   9476  C C   . LYS C 3 438 ? 177.710 181.623 107.791 1.00 223.79 ? 461 LYS C C   1 
ATOM   9477  O O   . LYS C 3 438 ? 177.068 182.675 107.703 1.00 223.79 ? 461 LYS C O   1 
ATOM   9478  C CB  . LYS C 3 438 ? 176.274 180.076 109.142 1.00 223.79 ? 461 LYS C CB  1 
ATOM   9479  C CG  . LYS C 3 438 ? 175.962 179.154 107.972 1.00 223.79 ? 461 LYS C CG  1 
ATOM   9480  C CD  . LYS C 3 438 ? 174.911 179.758 107.054 1.00 223.79 ? 461 LYS C CD  1 
ATOM   9481  C CE  . LYS C 3 438 ? 174.553 178.806 105.924 1.00 223.79 ? 461 LYS C CE  1 
ATOM   9482  N NZ  . LYS C 3 438 ? 173.553 179.400 104.994 1.00 223.79 ? 461 LYS C NZ  1 
ATOM   9483  N N   . ILE C 3 439 ? 178.494 181.168 106.820 1.00 234.84 ? 462 ILE C N   1 
ATOM   9484  C CA  . ILE C 3 439 ? 178.631 181.876 105.552 1.00 234.84 ? 462 ILE C CA  1 
ATOM   9485  C C   . ILE C 3 439 ? 177.397 181.610 104.701 1.00 234.84 ? 462 ILE C C   1 
ATOM   9486  O O   . ILE C 3 439 ? 177.025 180.454 104.467 1.00 234.84 ? 462 ILE C O   1 
ATOM   9487  C CB  . ILE C 3 439 ? 179.913 181.444 104.822 1.00 234.84 ? 462 ILE C CB  1 
ATOM   9488  C CG1 . ILE C 3 439 ? 181.140 181.715 105.695 1.00 234.84 ? 462 ILE C CG1 1 
ATOM   9489  C CG2 . ILE C 3 439 ? 180.035 182.162 103.487 1.00 234.84 ? 462 ILE C CG2 1 
ATOM   9490  C CD1 . ILE C 3 439 ? 181.316 183.171 106.068 1.00 234.84 ? 462 ILE C CD1 1 
ATOM   9491  N N   . ILE C 3 440 ? 176.758 182.682 104.235 1.00 243.91 ? 463 ILE C N   1 
ATOM   9492  C CA  . ILE C 3 440 ? 175.549 182.565 103.427 1.00 243.91 ? 463 ILE C CA  1 
ATOM   9493  C C   . ILE C 3 440 ? 175.917 182.605 101.951 1.00 243.91 ? 463 ILE C C   1 
ATOM   9494  O O   . ILE C 3 440 ? 175.652 181.654 101.207 1.00 243.91 ? 463 ILE C O   1 
ATOM   9495  C CB  . ILE C 3 440 ? 174.539 183.675 103.771 1.00 243.91 ? 463 ILE C CB  1 
ATOM   9496  C CG1 . ILE C 3 440 ? 174.150 183.602 105.249 1.00 243.91 ? 463 ILE C CG1 1 
ATOM   9497  C CG2 . ILE C 3 440 ? 173.309 183.568 102.884 1.00 243.91 ? 463 ILE C CG2 1 
ATOM   9498  C CD1 . ILE C 3 440 ? 173.151 184.658 105.668 1.00 243.91 ? 463 ILE C CD1 1 
ATOM   9499  N N   . SER C 3 441 ? 176.529 183.704 101.517 1.00 257.32 ? 464 SER C N   1 
ATOM   9500  C CA  . SER C 3 441 ? 176.910 183.868 100.123 1.00 257.32 ? 464 SER C CA  1 
ATOM   9501  C C   . SER C 3 441 ? 178.152 184.743 100.046 1.00 257.32 ? 464 SER C C   1 
ATOM   9502  O O   . SER C 3 441 ? 178.588 185.333 101.038 1.00 257.32 ? 464 SER C O   1 
ATOM   9503  C CB  . SER C 3 441 ? 175.767 184.471 99.298  1.00 257.32 ? 464 SER C CB  1 
ATOM   9504  O OG  . SER C 3 441 ? 175.971 184.260 97.912  1.00 257.32 ? 464 SER C OG  1 
ATOM   9505  N N   . TYR C 3 442 ? 178.721 184.819 98.846  1.00 259.71 ? 465 TYR C N   1 
ATOM   9506  C CA  . TYR C 3 442 ? 179.902 185.625 98.577  1.00 259.71 ? 465 TYR C CA  1 
ATOM   9507  C C   . TYR C 3 442 ? 179.559 186.707 97.563  1.00 259.71 ? 465 TYR C C   1 
ATOM   9508  O O   . TYR C 3 442 ? 178.867 186.447 96.574  1.00 259.71 ? 465 TYR C O   1 
ATOM   9509  C CB  . TYR C 3 442 ? 181.055 184.764 98.051  1.00 259.71 ? 465 TYR C CB  1 
ATOM   9510  C CG  . TYR C 3 442 ? 181.358 183.552 98.903  1.00 259.71 ? 465 TYR C CG  1 
ATOM   9511  C CD1 . TYR C 3 442 ? 182.203 183.644 100.000 1.00 259.71 ? 465 TYR C CD1 1 
ATOM   9512  C CD2 . TYR C 3 442 ? 180.800 182.315 98.607  1.00 259.71 ? 465 TYR C CD2 1 
ATOM   9513  C CE1 . TYR C 3 442 ? 182.484 182.539 100.780 1.00 259.71 ? 465 TYR C CE1 1 
ATOM   9514  C CE2 . TYR C 3 442 ? 181.074 181.204 99.382  1.00 259.71 ? 465 TYR C CE2 1 
ATOM   9515  C CZ  . TYR C 3 442 ? 181.916 181.322 100.467 1.00 259.71 ? 465 TYR C CZ  1 
ATOM   9516  O OH  . TYR C 3 442 ? 182.192 180.219 101.242 1.00 259.71 ? 465 TYR C OH  1 
ATOM   9517  N N   . ASN C 3 443 ? 180.045 187.919 97.814  1.00 265.02 ? 466 ASN C N   1 
ATOM   9518  C CA  . ASN C 3 443 ? 179.824 189.053 96.927  1.00 265.02 ? 466 ASN C CA  1 
ATOM   9519  C C   . ASN C 3 443 ? 181.036 189.236 96.025  1.00 265.02 ? 466 ASN C C   1 
ATOM   9520  O O   . ASN C 3 443 ? 182.168 189.335 96.510  1.00 265.02 ? 466 ASN C O   1 
ATOM   9521  C CB  . ASN C 3 443 ? 179.561 190.330 97.728  1.00 265.02 ? 466 ASN C CB  1 
ATOM   9522  C CG  . ASN C 3 443 ? 178.588 190.112 98.870  1.00 265.02 ? 466 ASN C CG  1 
ATOM   9523  O OD1 . ASN C 3 443 ? 177.377 190.268 98.708  1.00 265.02 ? 466 ASN C OD1 1 
ATOM   9524  N ND2 . ASN C 3 443 ? 179.114 189.755 100.036 1.00 265.02 ? 466 ASN C ND2 1 
ATOM   9525  N N   . ILE C 3 444 ? 180.797 189.281 94.717  1.00 270.45 ? 467 ILE C N   1 
ATOM   9526  C CA  . ILE C 3 444 ? 181.848 189.447 93.719  1.00 270.45 ? 467 ILE C CA  1 
ATOM   9527  C C   . ILE C 3 444 ? 181.598 190.767 93.005  1.00 270.45 ? 467 ILE C C   1 
ATOM   9528  O O   . ILE C 3 444 ? 180.626 190.899 92.250  1.00 270.45 ? 467 ILE C O   1 
ATOM   9529  C CB  . ILE C 3 444 ? 181.898 188.282 92.718  1.00 270.45 ? 467 ILE C CB  1 
ATOM   9530  C CG1 . ILE C 3 444 ? 182.046 186.936 93.438  1.00 270.45 ? 467 ILE C CG1 1 
ATOM   9531  C CG2 . ILE C 3 444 ? 183.034 188.485 91.724  1.00 270.45 ? 467 ILE C CG2 1 
ATOM   9532  C CD1 . ILE C 3 444 ? 180.734 186.273 93.821  1.00 270.45 ? 467 ILE C CD1 1 
ATOM   9533  N N   . VAL C 3 445 ? 182.472 191.741 93.238  1.00 268.18 ? 468 VAL C N   1 
ATOM   9534  C CA  . VAL C 3 445 ? 182.377 193.061 92.625  1.00 268.18 ? 468 VAL C CA  1 
ATOM   9535  C C   . VAL C 3 445 ? 183.563 193.213 91.683  1.00 268.18 ? 468 VAL C C   1 
ATOM   9536  O O   . VAL C 3 445 ? 184.713 193.311 92.128  1.00 268.18 ? 468 VAL C O   1 
ATOM   9537  C CB  . VAL C 3 445 ? 182.352 194.179 93.675  1.00 268.18 ? 468 VAL C CB  1 
ATOM   9538  C CG1 . VAL C 3 445 ? 182.426 195.541 93.002  1.00 268.18 ? 468 VAL C CG1 1 
ATOM   9539  C CG2 . VAL C 3 445 ? 181.102 194.070 94.536  1.00 268.18 ? 468 VAL C CG2 1 
ATOM   9540  N N   . VAL C 3 446 ? 183.288 193.230 90.382  1.00 268.51 ? 469 VAL C N   1 
ATOM   9541  C CA  . VAL C 3 446 ? 184.314 193.367 89.354  1.00 268.51 ? 469 VAL C CA  1 
ATOM   9542  C C   . VAL C 3 446 ? 184.196 194.762 88.756  1.00 268.51 ? 469 VAL C C   1 
ATOM   9543  O O   . VAL C 3 446 ? 183.140 195.133 88.229  1.00 268.51 ? 469 VAL C O   1 
ATOM   9544  C CB  . VAL C 3 446 ? 184.181 192.287 88.271  1.00 268.51 ? 469 VAL C CB  1 
ATOM   9545  C CG1 . VAL C 3 446 ? 185.403 192.290 87.369  1.00 268.51 ? 469 VAL C CG1 1 
ATOM   9546  C CG2 . VAL C 3 446 ? 183.984 190.920 88.909  1.00 268.51 ? 469 VAL C CG2 1 
ATOM   9547  N N   . GLU C 3 447 ? 185.278 195.533 88.837  1.00 272.69 ? 470 GLU C N   1 
ATOM   9548  C CA  . GLU C 3 447 ? 185.305 196.914 88.373  1.00 272.69 ? 470 GLU C CA  1 
ATOM   9549  C C   . GLU C 3 447 ? 186.307 197.052 87.236  1.00 272.69 ? 470 GLU C C   1 
ATOM   9550  O O   . GLU C 3 447 ? 187.440 196.572 87.341  1.00 272.69 ? 470 GLU C O   1 
ATOM   9551  C CB  . GLU C 3 447 ? 185.666 197.870 89.514  1.00 272.69 ? 470 GLU C CB  1 
ATOM   9552  C CG  . GLU C 3 447 ? 184.642 197.915 90.636  1.00 272.69 ? 470 GLU C CG  1 
ATOM   9553  C CD  . GLU C 3 447 ? 185.098 198.758 91.810  1.00 272.69 ? 470 GLU C CD  1 
ATOM   9554  O OE1 . GLU C 3 447 ? 184.959 198.299 92.963  1.00 272.69 ? 470 GLU C OE1 1 
ATOM   9555  O OE2 . GLU C 3 447 ? 185.595 199.881 91.580  1.00 272.69 ? 470 GLU C OE2 1 
ATOM   9556  N N   . ASN C 3 448 ? 185.888 197.707 86.157  1.00 279.89 ? 471 ASN C N   1 
ATOM   9557  C CA  . ASN C 3 448 ? 186.758 197.962 85.018  1.00 279.89 ? 471 ASN C CA  1 
ATOM   9558  C C   . ASN C 3 448 ? 187.462 199.302 85.179  1.00 279.89 ? 471 ASN C C   1 
ATOM   9559  O O   . ASN C 3 448 ? 186.869 200.278 85.648  1.00 279.89 ? 471 ASN C O   1 
ATOM   9560  C CB  . ASN C 3 448 ? 185.961 197.945 83.713  1.00 279.89 ? 471 ASN C CB  1 
ATOM   9561  C CG  . ASN C 3 448 ? 186.695 197.237 82.591  1.00 279.89 ? 471 ASN C CG  1 
ATOM   9562  O OD1 . ASN C 3 448 ? 187.536 196.373 82.831  1.00 279.89 ? 471 ASN C OD1 1 
ATOM   9563  N ND2 . ASN C 3 448 ? 186.377 197.602 81.354  1.00 279.89 ? 471 ASN C ND2 1 
ATOM   9564  N N   . GLU C 3 449 ? 188.737 199.342 84.787  1.00 279.45 ? 472 GLU C N   1 
ATOM   9565  C CA  . GLU C 3 449 ? 189.495 200.586 84.871  1.00 279.45 ? 472 GLU C CA  1 
ATOM   9566  C C   . GLU C 3 449 ? 189.094 201.553 83.764  1.00 279.45 ? 472 GLU C C   1 
ATOM   9567  O O   . GLU C 3 449 ? 189.110 202.773 83.961  1.00 279.45 ? 472 GLU C O   1 
ATOM   9568  C CB  . GLU C 3 449 ? 190.994 200.294 84.814  1.00 279.45 ? 472 GLU C CB  1 
ATOM   9569  C CG  . GLU C 3 449 ? 191.415 199.055 85.586  1.00 279.45 ? 472 GLU C CG  1 
ATOM   9570  C CD  . GLU C 3 449 ? 192.910 199.003 85.833  1.00 279.45 ? 472 GLU C CD  1 
ATOM   9571  O OE1 . GLU C 3 449 ? 193.504 200.064 86.120  1.00 279.45 ? 472 GLU C OE1 1 
ATOM   9572  O OE2 . GLU C 3 449 ? 193.492 197.902 85.744  1.00 279.45 ? 472 GLU C OE2 1 
ATOM   9573  N N   . ALA C 3 450 ? 188.732 201.027 82.591  1.00 281.27 ? 473 ALA C N   1 
ATOM   9574  C CA  . ALA C 3 450 ? 188.320 201.893 81.492  1.00 281.27 ? 473 ALA C CA  1 
ATOM   9575  C C   . ALA C 3 450 ? 186.938 202.488 81.731  1.00 281.27 ? 473 ALA C C   1 
ATOM   9576  O O   . ALA C 3 450 ? 186.652 203.595 81.261  1.00 281.27 ? 473 ALA C O   1 
ATOM   9577  C CB  . ALA C 3 450 ? 188.344 201.119 80.174  1.00 281.27 ? 473 ALA C CB  1 
ATOM   9578  N N   . LYS C 3 451 ? 186.074 201.777 82.455  1.00 280.14 ? 474 LYS C N   1 
ATOM   9579  C CA  . LYS C 3 451 ? 184.730 202.259 82.765  1.00 280.14 ? 474 LYS C CA  1 
ATOM   9580  C C   . LYS C 3 451 ? 184.422 201.952 84.223  1.00 280.14 ? 474 LYS C C   1 
ATOM   9581  O O   . LYS C 3 451 ? 183.835 200.911 84.546  1.00 280.14 ? 474 LYS C O   1 
ATOM   9582  C CB  . LYS C 3 451 ? 183.685 201.636 81.838  1.00 280.14 ? 474 LYS C CB  1 
ATOM   9583  C CG  . LYS C 3 451 ? 183.955 200.184 81.473  1.00 280.14 ? 474 LYS C CG  1 
ATOM   9584  C CD  . LYS C 3 451 ? 182.837 199.615 80.613  1.00 280.14 ? 474 LYS C CD  1 
ATOM   9585  C CE  . LYS C 3 451 ? 183.017 198.123 80.387  1.00 280.14 ? 474 LYS C CE  1 
ATOM   9586  N NZ  . LYS C 3 451 ? 182.979 197.361 81.666  1.00 280.14 ? 474 LYS C NZ  1 
ATOM   9587  N N   . PRO C 3 452 ? 184.806 202.845 85.140  1.00 277.18 ? 475 PRO C N   1 
ATOM   9588  C CA  . PRO C 3 452 ? 184.521 202.607 86.564  1.00 277.18 ? 475 PRO C CA  1 
ATOM   9589  C C   . PRO C 3 452 ? 183.057 202.778 86.932  1.00 277.18 ? 475 PRO C C   1 
ATOM   9590  O O   . PRO C 3 452 ? 182.677 202.421 88.055  1.00 277.18 ? 475 PRO C O   1 
ATOM   9591  C CB  . PRO C 3 452 ? 185.396 203.647 87.273  1.00 277.18 ? 475 PRO C CB  1 
ATOM   9592  C CG  . PRO C 3 452 ? 185.530 204.752 86.280  1.00 277.18 ? 475 PRO C CG  1 
ATOM   9593  C CD  . PRO C 3 452 ? 185.543 204.102 84.922  1.00 277.18 ? 475 PRO C CD  1 
ATOM   9594  N N   . THR C 3 453 ? 182.228 203.309 86.032  1.00 277.29 ? 476 THR C N   1 
ATOM   9595  C CA  . THR C 3 453 ? 180.811 203.480 86.335  1.00 277.29 ? 476 THR C CA  1 
ATOM   9596  C C   . THR C 3 453 ? 180.033 202.186 86.130  1.00 277.29 ? 476 THR C C   1 
ATOM   9597  O O   . THR C 3 453 ? 179.153 201.854 86.932  1.00 277.29 ? 476 THR C O   1 
ATOM   9598  C CB  . THR C 3 453 ? 180.219 204.596 85.474  1.00 277.29 ? 476 THR C CB  1 
ATOM   9599  O OG1 . THR C 3 453 ? 180.696 204.469 84.128  1.00 277.29 ? 476 THR C OG1 1 
ATOM   9600  C CG2 . THR C 3 453 ? 180.618 205.959 86.021  1.00 277.29 ? 476 THR C CG2 1 
ATOM   9601  N N   . GLU C 3 454 ? 180.342 201.445 85.067  1.00 278.20 ? 477 GLU C N   1 
ATOM   9602  C CA  . GLU C 3 454 ? 179.659 200.187 84.766  1.00 278.20 ? 477 GLU C CA  1 
ATOM   9603  C C   . GLU C 3 454 ? 180.391 199.065 85.492  1.00 278.20 ? 477 GLU C C   1 
ATOM   9604  O O   . GLU C 3 454 ? 181.412 198.555 85.029  1.00 278.20 ? 477 GLU C O   1 
ATOM   9605  C CB  . GLU C 3 454 ? 179.603 199.948 83.262  1.00 278.20 ? 477 GLU C CB  1 
ATOM   9606  C CG  . GLU C 3 454 ? 179.046 198.588 82.867  1.00 278.20 ? 477 GLU C CG  1 
ATOM   9607  C CD  . GLU C 3 454 ? 177.679 198.319 83.466  1.00 278.20 ? 477 GLU C CD  1 
ATOM   9608  O OE1 . GLU C 3 454 ? 176.819 199.223 83.420  1.00 278.20 ? 477 GLU C OE1 1 
ATOM   9609  O OE2 . GLU C 3 454 ? 177.465 197.203 83.984  1.00 278.20 ? 477 GLU C OE2 1 
ATOM   9610  N N   . SER C 3 455 ? 179.864 198.683 86.650  1.00 274.57 ? 478 SER C N   1 
ATOM   9611  C CA  . SER C 3 455 ? 180.425 197.614 87.464  1.00 274.57 ? 478 SER C CA  1 
ATOM   9612  C C   . SER C 3 455 ? 179.406 196.491 87.591  1.00 274.57 ? 478 SER C C   1 
ATOM   9613  O O   . SER C 3 455 ? 178.223 196.746 87.837  1.00 274.57 ? 478 SER C O   1 
ATOM   9614  C CB  . SER C 3 455 ? 180.825 198.130 88.848  1.00 274.57 ? 478 SER C CB  1 
ATOM   9615  O OG  . SER C 3 455 ? 182.083 198.781 88.804  1.00 274.57 ? 478 SER C OG  1 
ATOM   9616  N N   . GLU C 3 456 ? 179.866 195.255 87.424  1.00 271.05 ? 479 GLU C N   1 
ATOM   9617  C CA  . GLU C 3 456 ? 179.006 194.084 87.498  1.00 271.05 ? 479 GLU C CA  1 
ATOM   9618  C C   . GLU C 3 456 ? 179.031 193.503 88.905  1.00 271.05 ? 479 GLU C C   1 
ATOM   9619  O O   . GLU C 3 456 ? 180.063 193.527 89.582  1.00 271.05 ? 479 GLU C O   1 
ATOM   9620  C CB  . GLU C 3 456 ? 179.442 193.023 86.485  1.00 271.05 ? 479 GLU C CB  1 
ATOM   9621  C CG  . GLU C 3 456 ? 180.922 192.679 86.539  1.00 271.05 ? 479 GLU C CG  1 
ATOM   9622  C CD  . GLU C 3 456 ? 181.342 191.731 85.433  1.00 271.05 ? 479 GLU C CD  1 
ATOM   9623  O OE1 . GLU C 3 456 ? 180.462 191.271 84.675  1.00 271.05 ? 479 GLU C OE1 1 
ATOM   9624  O OE2 . GLU C 3 456 ? 182.553 191.445 85.320  1.00 271.05 ? 479 GLU C OE2 1 
ATOM   9625  N N   . HIS C 3 457 ? 177.886 192.983 89.340  1.00 269.00 ? 480 HIS C N   1 
ATOM   9626  C CA  . HIS C 3 457 ? 177.737 192.381 90.657  1.00 269.00 ? 480 HIS C CA  1 
ATOM   9627  C C   . HIS C 3 457 ? 177.286 190.937 90.498  1.00 269.00 ? 480 HIS C C   1 
ATOM   9628  O O   . HIS C 3 457 ? 176.285 190.666 89.827  1.00 269.00 ? 480 HIS C O   1 
ATOM   9629  C CB  . HIS C 3 457 ? 176.733 193.162 91.510  1.00 269.00 ? 480 HIS C CB  1 
ATOM   9630  C CG  . HIS C 3 457 ? 176.687 192.727 92.942  1.00 269.00 ? 480 HIS C CG  1 
ATOM   9631  N ND1 . HIS C 3 457 ? 175.695 193.129 93.811  1.00 269.00 ? 480 HIS C ND1 1 
ATOM   9632  C CD2 . HIS C 3 457 ? 177.511 191.925 93.658  1.00 269.00 ? 480 HIS C CD2 1 
ATOM   9633  C CE1 . HIS C 3 457 ? 175.910 192.594 94.999  1.00 269.00 ? 480 HIS C CE1 1 
ATOM   9634  N NE2 . HIS C 3 457 ? 177.005 191.859 94.933  1.00 269.00 ? 480 HIS C NE2 1 
ATOM   9635  N N   . TYR C 3 458 ? 178.025 190.017 91.114  1.00 269.22 ? 481 TYR C N   1 
ATOM   9636  C CA  . TYR C 3 458 ? 177.718 188.595 91.060  1.00 269.22 ? 481 TYR C CA  1 
ATOM   9637  C C   . TYR C 3 458 ? 177.634 188.042 92.474  1.00 269.22 ? 481 TYR C C   1 
ATOM   9638  O O   . TYR C 3 458 ? 178.359 188.487 93.369  1.00 269.22 ? 481 TYR C O   1 
ATOM   9639  C CB  . TYR C 3 458 ? 178.774 187.824 90.257  1.00 269.22 ? 481 TYR C CB  1 
ATOM   9640  C CG  . TYR C 3 458 ? 178.629 187.969 88.758  1.00 269.22 ? 481 TYR C CG  1 
ATOM   9641  C CD1 . TYR C 3 458 ? 177.950 187.015 88.012  1.00 269.22 ? 481 TYR C CD1 1 
ATOM   9642  C CD2 . TYR C 3 458 ? 179.171 189.059 88.091  1.00 269.22 ? 481 TYR C CD2 1 
ATOM   9643  C CE1 . TYR C 3 458 ? 177.815 187.142 86.642  1.00 269.22 ? 481 TYR C CE1 1 
ATOM   9644  C CE2 . TYR C 3 458 ? 179.041 189.195 86.722  1.00 269.22 ? 481 TYR C CE2 1 
ATOM   9645  C CZ  . TYR C 3 458 ? 178.363 188.234 86.003  1.00 269.22 ? 481 TYR C CZ  1 
ATOM   9646  O OH  . TYR C 3 458 ? 178.231 188.366 84.639  1.00 269.22 ? 481 TYR C OH  1 
ATOM   9647  N N   . CYS C 3 459 ? 176.744 187.071 92.671  1.00 273.16 ? 482 CYS C N   1 
ATOM   9648  C CA  . CYS C 3 459 ? 176.531 186.449 93.972  1.00 273.16 ? 482 CYS C CA  1 
ATOM   9649  C C   . CYS C 3 459 ? 176.642 184.941 93.822  1.00 273.16 ? 482 CYS C C   1 
ATOM   9650  O O   . CYS C 3 459 ? 175.824 184.322 93.133  1.00 273.16 ? 482 CYS C O   1 
ATOM   9651  C CB  . CYS C 3 459 ? 175.167 186.833 94.552  1.00 273.16 ? 482 CYS C CB  1 
ATOM   9652  S SG  . CYS C 3 459 ? 174.644 185.826 95.959  1.00 273.16 ? 482 CYS C SG  1 
ATOM   9653  N N   . VAL C 3 460 ? 177.649 184.354 94.463  1.00 269.47 ? 483 VAL C N   1 
ATOM   9654  C CA  . VAL C 3 460 ? 177.860 182.911 94.466  1.00 269.47 ? 483 VAL C CA  1 
ATOM   9655  C C   . VAL C 3 460 ? 177.481 182.389 95.845  1.00 269.47 ? 483 VAL C C   1 
ATOM   9656  O O   . VAL C 3 460 ? 178.084 182.781 96.852  1.00 269.47 ? 483 VAL C O   1 
ATOM   9657  C CB  . VAL C 3 460 ? 179.310 182.547 94.114  1.00 269.47 ? 483 VAL C CB  1 
ATOM   9658  C CG1 . VAL C 3 460 ? 179.561 181.070 94.367  1.00 269.47 ? 483 VAL C CG1 1 
ATOM   9659  C CG2 . VAL C 3 460 ? 179.607 182.900 92.664  1.00 269.47 ? 483 VAL C CG2 1 
ATOM   9660  N N   . TRP C 3 461 ? 176.485 181.510 95.890  1.00 266.56 ? 484 TRP C N   1 
ATOM   9661  C CA  . TRP C 3 461 ? 175.978 181.005 97.156  1.00 266.56 ? 484 TRP C CA  1 
ATOM   9662  C C   . TRP C 3 461 ? 176.856 179.877 97.687  1.00 266.56 ? 484 TRP C C   1 
ATOM   9663  O O   . TRP C 3 461 ? 177.468 179.123 96.926  1.00 266.56 ? 484 TRP C O   1 
ATOM   9664  C CB  . TRP C 3 461 ? 174.538 180.513 96.998  1.00 266.56 ? 484 TRP C CB  1 
ATOM   9665  C CG  . TRP C 3 461 ? 173.592 181.579 96.539  1.00 266.56 ? 484 TRP C CG  1 
ATOM   9666  C CD1 . TRP C 3 461 ? 173.284 181.902 95.250  1.00 266.56 ? 484 TRP C CD1 1 
ATOM   9667  C CD2 . TRP C 3 461 ? 172.831 182.467 97.368  1.00 266.56 ? 484 TRP C CD2 1 
ATOM   9668  N NE1 . TRP C 3 461 ? 172.377 182.934 95.224  1.00 266.56 ? 484 TRP C NE1 1 
ATOM   9669  C CE2 . TRP C 3 461 ? 172.083 183.299 96.511  1.00 266.56 ? 484 TRP C CE2 1 
ATOM   9670  C CE3 . TRP C 3 461 ? 172.709 182.637 98.750  1.00 266.56 ? 484 TRP C CE3 1 
ATOM   9671  C CZ2 . TRP C 3 461 ? 171.226 184.287 96.992  1.00 266.56 ? 484 TRP C CZ2 1 
ATOM   9672  C CZ3 . TRP C 3 461 ? 171.858 183.619 99.225  1.00 266.56 ? 484 TRP C CZ3 1 
ATOM   9673  C CH2 . TRP C 3 461 ? 171.127 184.431 98.348  1.00 266.56 ? 484 TRP C CH2 1 
ATOM   9674  N N   . ALA C 3 462 ? 176.910 179.774 99.012  1.00 261.31 ? 485 ALA C N   1 
ATOM   9675  C CA  . ALA C 3 462 ? 177.673 178.718 99.654  1.00 261.31 ? 485 ALA C CA  1 
ATOM   9676  C C   . ALA C 3 462 ? 177.000 177.364 99.424  1.00 261.31 ? 485 ALA C C   1 
ATOM   9677  O O   . ALA C 3 462 ? 175.783 177.292 99.234  1.00 261.31 ? 485 ALA C O   1 
ATOM   9678  C CB  . ALA C 3 462 ? 177.801 178.994 101.150 1.00 261.31 ? 485 ALA C CB  1 
ATOM   9679  N N   . PRO C 3 463 ? 177.773 176.264 99.436  1.00 256.68 ? 486 PRO C N   1 
ATOM   9680  C CA  . PRO C 3 463 ? 179.227 176.208 99.612  1.00 256.68 ? 486 PRO C CA  1 
ATOM   9681  C C   . PRO C 3 463 ? 179.998 176.103 98.299  1.00 256.68 ? 486 PRO C C   1 
ATOM   9682  O O   . PRO C 3 463 ? 180.995 175.383 98.237  1.00 256.68 ? 486 PRO C O   1 
ATOM   9683  C CB  . PRO C 3 463 ? 179.412 174.943 100.444 1.00 256.68 ? 486 PRO C CB  1 
ATOM   9684  C CG  . PRO C 3 463 ? 178.329 174.034 99.938  1.00 256.68 ? 486 PRO C CG  1 
ATOM   9685  C CD  . PRO C 3 463 ? 177.183 174.914 99.462  1.00 256.68 ? 486 PRO C CD  1 
ATOM   9686  N N   . ALA C 3 464 ? 179.542 176.807 97.266  1.00 258.21 ? 487 ALA C N   1 
ATOM   9687  C CA  . ALA C 3 464 ? 180.233 176.779 95.984  1.00 258.21 ? 487 ALA C CA  1 
ATOM   9688  C C   . ALA C 3 464 ? 181.573 177.497 96.095  1.00 258.21 ? 487 ALA C C   1 
ATOM   9689  O O   . ALA C 3 464 ? 181.655 178.602 96.639  1.00 258.21 ? 487 ALA C O   1 
ATOM   9690  C CB  . ALA C 3 464 ? 179.371 177.423 94.900  1.00 258.21 ? 487 ALA C CB  1 
ATOM   9691  N N   . LEU C 3 465 ? 182.626 176.863 95.579  1.00 257.71 ? 488 LEU C N   1 
ATOM   9692  C CA  . LEU C 3 465 ? 183.978 177.401 95.662  1.00 257.71 ? 488 LEU C CA  1 
ATOM   9693  C C   . LEU C 3 465 ? 184.581 177.700 94.295  1.00 257.71 ? 488 LEU C C   1 
ATOM   9694  O O   . LEU C 3 465 ? 185.805 177.840 94.189  1.00 257.71 ? 488 LEU C O   1 
ATOM   9695  C CB  . LEU C 3 465 ? 184.887 176.438 96.431  1.00 257.71 ? 488 LEU C CB  1 
ATOM   9696  C CG  . LEU C 3 465 ? 184.435 176.056 97.842  1.00 257.71 ? 488 LEU C CG  1 
ATOM   9697  C CD1 . LEU C 3 465 ? 185.422 175.088 98.474  1.00 257.71 ? 488 LEU C CD1 1 
ATOM   9698  C CD2 . LEU C 3 465 ? 184.265 177.294 98.707  1.00 257.71 ? 488 LEU C CD2 1 
ATOM   9699  N N   . SER C 3 466 ? 183.764 177.800 93.249  1.00 260.94 ? 489 SER C N   1 
ATOM   9700  C CA  . SER C 3 466 ? 184.274 178.066 91.913  1.00 260.94 ? 489 SER C CA  1 
ATOM   9701  C C   . SER C 3 466 ? 183.203 178.765 91.089  1.00 260.94 ? 489 SER C C   1 
ATOM   9702  O O   . SER C 3 466 ? 182.007 178.507 91.251  1.00 260.94 ? 489 SER C O   1 
ATOM   9703  C CB  . SER C 3 466 ? 184.722 176.777 91.214  1.00 260.94 ? 489 SER C CB  1 
ATOM   9704  O OG  . SER C 3 466 ? 184.888 176.983 89.822  1.00 260.94 ? 489 SER C OG  1 
ATOM   9705  N N   . THR C 3 467 ? 183.649 179.653 90.204  1.00 262.26 ? 490 THR C N   1 
ATOM   9706  C CA  . THR C 3 467 ? 182.759 180.358 89.294  1.00 262.26 ? 490 THR C CA  1 
ATOM   9707  C C   . THR C 3 467 ? 183.545 180.754 88.053  1.00 262.26 ? 490 THR C C   1 
ATOM   9708  O O   . THR C 3 467 ? 184.776 180.827 88.071  1.00 262.26 ? 490 THR C O   1 
ATOM   9709  C CB  . THR C 3 467 ? 182.133 181.596 89.951  1.00 262.26 ? 490 THR C CB  1 
ATOM   9710  O OG1 . THR C 3 467 ? 181.245 182.234 89.025  1.00 262.26 ? 490 THR C OG1 1 
ATOM   9711  C CG2 . THR C 3 467 ? 183.212 182.581 90.372  1.00 262.26 ? 490 THR C CG2 1 
ATOM   9712  N N   . ASN C 3 468 ? 182.816 181.010 86.969  1.00 259.15 ? 491 ASN C N   1 
ATOM   9713  C CA  . ASN C 3 468 ? 183.410 181.360 85.686  1.00 259.15 ? 491 ASN C CA  1 
ATOM   9714  C C   . ASN C 3 468 ? 182.884 182.712 85.228  1.00 259.15 ? 491 ASN C C   1 
ATOM   9715  O O   . ASN C 3 468 ? 181.675 182.965 85.282  1.00 259.15 ? 491 ASN C O   1 
ATOM   9716  C CB  . ASN C 3 468 ? 183.117 180.287 84.632  1.00 259.15 ? 491 ASN C CB  1 
ATOM   9717  C CG  . ASN C 3 468 ? 181.692 179.772 84.701  1.00 259.15 ? 491 ASN C CG  1 
ATOM   9718  O OD1 . ASN C 3 468 ? 180.869 180.283 85.460  1.00 259.15 ? 491 ASN C OD1 1 
ATOM   9719  N ND2 . ASN C 3 468 ? 181.393 178.752 83.904  1.00 259.15 ? 491 ASN C ND2 1 
ATOM   9720  N N   . LEU C 3 469 ? 183.793 183.576 84.784  1.00 264.06 ? 492 LEU C N   1 
ATOM   9721  C CA  . LEU C 3 469 ? 183.452 184.892 84.265  1.00 264.06 ? 492 LEU C CA  1 
ATOM   9722  C C   . LEU C 3 469 ? 184.018 185.055 82.861  1.00 264.06 ? 492 LEU C C   1 
ATOM   9723  O O   . LEU C 3 469 ? 185.095 184.540 82.543  1.00 264.06 ? 492 LEU C O   1 
ATOM   9724  C CB  . LEU C 3 469 ? 183.983 186.016 85.169  1.00 264.06 ? 492 LEU C CB  1 
ATOM   9725  C CG  . LEU C 3 469 ? 183.113 186.495 86.337  1.00 264.06 ? 492 LEU C CG  1 
ATOM   9726  C CD1 . LEU C 3 469 ? 181.816 187.101 85.820  1.00 264.06 ? 492 LEU C CD1 1 
ATOM   9727  C CD2 . LEU C 3 469 ? 182.831 185.384 87.337  1.00 264.06 ? 492 LEU C CD2 1 
ATOM   9728  N N   . SER C 3 470 ? 183.281 185.780 82.024  1.00 273.69 ? 493 SER C N   1 
ATOM   9729  C CA  . SER C 3 470 ? 183.664 186.036 80.640  1.00 273.69 ? 493 SER C CA  1 
ATOM   9730  C C   . SER C 3 470 ? 183.987 187.518 80.498  1.00 273.69 ? 493 SER C C   1 
ATOM   9731  O O   . SER C 3 470 ? 183.087 188.363 80.548  1.00 273.69 ? 493 SER C O   1 
ATOM   9732  C CB  . SER C 3 470 ? 182.552 185.620 79.679  1.00 273.69 ? 493 SER C CB  1 
ATOM   9733  O OG  . SER C 3 470 ? 182.581 184.224 79.439  1.00 273.69 ? 493 SER C OG  1 
ATOM   9734  N N   . LEU C 3 471 ? 185.269 187.830 80.322  1.00 278.87 ? 494 LEU C N   1 
ATOM   9735  C CA  . LEU C 3 471 ? 185.729 189.202 80.181  1.00 278.87 ? 494 LEU C CA  1 
ATOM   9736  C C   . LEU C 3 471 ? 186.607 189.321 78.943  1.00 278.87 ? 494 LEU C C   1 
ATOM   9737  O O   . LEU C 3 471 ? 187.095 188.326 78.402  1.00 278.87 ? 494 LEU C O   1 
ATOM   9738  C CB  . LEU C 3 471 ? 186.503 189.668 81.423  1.00 278.87 ? 494 LEU C CB  1 
ATOM   9739  C CG  . LEU C 3 471 ? 185.751 189.600 82.754  1.00 278.87 ? 494 LEU C CG  1 
ATOM   9740  C CD1 . LEU C 3 471 ? 186.675 189.935 83.915  1.00 278.87 ? 494 LEU C CD1 1 
ATOM   9741  C CD2 . LEU C 3 471 ? 184.546 190.528 82.738  1.00 278.87 ? 494 LEU C CD2 1 
ATOM   9742  N N   . ASP C 3 472 ? 186.800 190.559 78.498  1.00 282.52 ? 495 ASP C N   1 
ATOM   9743  C CA  . ASP C 3 472 ? 187.637 190.844 77.344  1.00 282.52 ? 495 ASP C CA  1 
ATOM   9744  C C   . ASP C 3 472 ? 189.068 191.117 77.807  1.00 282.52 ? 495 ASP C C   1 
ATOM   9745  O O   . ASP C 3 472 ? 189.428 190.883 78.964  1.00 282.52 ? 495 ASP C O   1 
ATOM   9746  C CB  . ASP C 3 472 ? 187.058 192.010 76.546  1.00 282.52 ? 495 ASP C CB  1 
ATOM   9747  C CG  . ASP C 3 472 ? 186.738 193.211 77.414  1.00 282.52 ? 495 ASP C CG  1 
ATOM   9748  O OD1 . ASP C 3 472 ? 186.844 193.097 78.653  1.00 282.52 ? 495 ASP C OD1 1 
ATOM   9749  O OD2 . ASP C 3 472 ? 186.381 194.270 76.857  1.00 282.52 ? 495 ASP C OD2 1 
ATOM   9750  N N   . LEU C 3 473 ? 189.904 191.619 76.899  1.00 281.59 ? 496 LEU C N   1 
ATOM   9751  C CA  . LEU C 3 473 ? 191.297 191.914 77.211  1.00 281.59 ? 496 LEU C CA  1 
ATOM   9752  C C   . LEU C 3 473 ? 191.471 193.175 78.047  1.00 281.59 ? 496 LEU C C   1 
ATOM   9753  O O   . LEU C 3 473 ? 192.610 193.533 78.365  1.00 281.59 ? 496 LEU C O   1 
ATOM   9754  C CB  . LEU C 3 473 ? 192.108 192.031 75.915  1.00 281.59 ? 496 LEU C CB  1 
ATOM   9755  C CG  . LEU C 3 473 ? 191.704 193.112 74.908  1.00 281.59 ? 496 LEU C CG  1 
ATOM   9756  C CD1 . LEU C 3 473 ? 192.535 194.378 75.082  1.00 281.59 ? 496 LEU C CD1 1 
ATOM   9757  C CD2 . LEU C 3 473 ? 191.816 192.586 73.484  1.00 281.59 ? 496 LEU C CD2 1 
ATOM   9758  N N   . GLN C 3 474 ? 190.386 193.852 78.408  1.00 282.61 ? 497 GLN C N   1 
ATOM   9759  C CA  . GLN C 3 474 ? 190.500 195.055 79.218  1.00 282.61 ? 497 GLN C CA  1 
ATOM   9760  C C   . GLN C 3 474 ? 190.869 194.687 80.654  1.00 282.61 ? 497 GLN C C   1 
ATOM   9761  O O   . GLN C 3 474 ? 190.425 193.654 81.165  1.00 282.61 ? 497 GLN C O   1 
ATOM   9762  C CB  . GLN C 3 474 ? 189.191 195.843 79.198  1.00 282.61 ? 497 GLN C CB  1 
ATOM   9763  C CG  . GLN C 3 474 ? 188.804 196.370 77.826  1.00 282.61 ? 497 GLN C CG  1 
ATOM   9764  C CD  . GLN C 3 474 ? 187.522 197.179 77.853  1.00 282.61 ? 497 GLN C CD  1 
ATOM   9765  O OE1 . GLN C 3 474 ? 186.927 197.386 78.911  1.00 282.61 ? 497 GLN C OE1 1 
ATOM   9766  N NE2 . GLN C 3 474 ? 187.090 197.642 76.686  1.00 282.61 ? 497 GLN C NE2 1 
ATOM   9767  N N   . PRO C 3 475 ? 191.678 195.505 81.327  1.00 281.70 ? 498 PRO C N   1 
ATOM   9768  C CA  . PRO C 3 475 ? 192.054 195.192 82.712  1.00 281.70 ? 498 PRO C CA  1 
ATOM   9769  C C   . PRO C 3 475 ? 190.888 195.424 83.663  1.00 281.70 ? 498 PRO C C   1 
ATOM   9770  O O   . PRO C 3 475 ? 190.288 196.501 83.682  1.00 281.70 ? 498 PRO C O   1 
ATOM   9771  C CB  . PRO C 3 475 ? 193.214 196.155 82.992  1.00 281.70 ? 498 PRO C CB  1 
ATOM   9772  C CG  . PRO C 3 475 ? 192.980 197.299 82.062  1.00 281.70 ? 498 PRO C CG  1 
ATOM   9773  C CD  . PRO C 3 475 ? 192.344 196.721 80.828  1.00 281.70 ? 498 PRO C CD  1 
ATOM   9774  N N   . TYR C 3 476 ? 190.571 194.402 84.452  1.00 277.63 ? 499 TYR C N   1 
ATOM   9775  C CA  . TYR C 3 476 ? 189.484 194.456 85.416  1.00 277.63 ? 499 TYR C CA  1 
ATOM   9776  C C   . TYR C 3 476 ? 190.035 194.434 86.836  1.00 277.63 ? 499 TYR C C   1 
ATOM   9777  O O   . TYR C 3 476 ? 191.166 194.000 87.077  1.00 277.63 ? 499 TYR C O   1 
ATOM   9778  C CB  . TYR C 3 476 ? 188.514 193.285 85.222  1.00 277.63 ? 499 TYR C CB  1 
ATOM   9779  C CG  . TYR C 3 476 ? 187.491 193.499 84.130  1.00 277.63 ? 499 TYR C CG  1 
ATOM   9780  C CD1 . TYR C 3 476 ? 186.236 194.021 84.419  1.00 277.63 ? 499 TYR C CD1 1 
ATOM   9781  C CD2 . TYR C 3 476 ? 187.776 193.173 82.811  1.00 277.63 ? 499 TYR C CD2 1 
ATOM   9782  C CE1 . TYR C 3 476 ? 185.296 194.216 83.424  1.00 277.63 ? 499 TYR C CE1 1 
ATOM   9783  C CE2 . TYR C 3 476 ? 186.843 193.364 81.810  1.00 277.63 ? 499 TYR C CE2 1 
ATOM   9784  C CZ  . TYR C 3 476 ? 185.605 193.886 82.121  1.00 277.63 ? 499 TYR C CZ  1 
ATOM   9785  O OH  . TYR C 3 476 ? 184.674 194.077 81.127  1.00 277.63 ? 499 TYR C OH  1 
ATOM   9786  N N   . LYS C 3 477 ? 189.221 194.908 87.776  1.00 269.58 ? 500 LYS C N   1 
ATOM   9787  C CA  . LYS C 3 477 ? 189.550 194.901 89.196  1.00 269.58 ? 500 LYS C CA  1 
ATOM   9788  C C   . LYS C 3 477 ? 188.425 194.199 89.941  1.00 269.58 ? 500 LYS C C   1 
ATOM   9789  O O   . LYS C 3 477 ? 187.271 194.639 89.885  1.00 269.58 ? 500 LYS C O   1 
ATOM   9790  C CB  . LYS C 3 477 ? 189.749 196.323 89.723  1.00 269.58 ? 500 LYS C CB  1 
ATOM   9791  C CG  . LYS C 3 477 ? 190.133 196.396 91.192  1.00 269.58 ? 500 LYS C CG  1 
ATOM   9792  C CD  . LYS C 3 477 ? 190.299 197.838 91.646  1.00 269.58 ? 500 LYS C CD  1 
ATOM   9793  C CE  . LYS C 3 477 ? 191.391 198.543 90.857  1.00 269.58 ? 500 LYS C CE  1 
ATOM   9794  N NZ  . LYS C 3 477 ? 192.711 197.872 91.014  1.00 269.58 ? 500 LYS C NZ  1 
ATOM   9795  N N   . ILE C 3 478 ? 188.758 193.117 90.637  1.00 265.48 ? 501 ILE C N   1 
ATOM   9796  C CA  . ILE C 3 478 ? 187.767 192.282 91.291  1.00 265.48 ? 501 ILE C CA  1 
ATOM   9797  C C   . ILE C 3 478 ? 187.751 192.583 92.784  1.00 265.48 ? 501 ILE C C   1 
ATOM   9798  O O   . ILE C 3 478 ? 188.721 193.083 93.361  1.00 265.48 ? 501 ILE C O   1 
ATOM   9799  C CB  . ILE C 3 478 ? 188.029 190.781 91.034  1.00 265.48 ? 501 ILE C CB  1 
ATOM   9800  C CG1 . ILE C 3 478 ? 189.321 190.340 91.724  1.00 265.48 ? 501 ILE C CG1 1 
ATOM   9801  C CG2 . ILE C 3 478 ? 188.091 190.499 89.540  1.00 265.48 ? 501 ILE C CG2 1 
ATOM   9802  C CD1 . ILE C 3 478 ? 189.589 188.855 91.634  1.00 265.48 ? 501 ILE C CD1 1 
ATOM   9803  N N   . ARG C 3 479 ? 186.622 192.273 93.419  1.00 260.90 ? 502 ARG C N   1 
ATOM   9804  C CA  . ARG C 3 479 ? 186.460 192.457 94.858  1.00 260.90 ? 502 ARG C CA  1 
ATOM   9805  C C   . ARG C 3 479 ? 185.575 191.338 95.382  1.00 260.90 ? 502 ARG C C   1 
ATOM   9806  O O   . ARG C 3 479 ? 184.416 191.222 94.972  1.00 260.90 ? 502 ARG C O   1 
ATOM   9807  C CB  . ARG C 3 479 ? 185.849 193.824 95.176  1.00 260.90 ? 502 ARG C CB  1 
ATOM   9808  C CG  . ARG C 3 479 ? 186.862 194.952 95.282  1.00 260.90 ? 502 ARG C CG  1 
ATOM   9809  C CD  . ARG C 3 479 ? 187.766 194.771 96.490  1.00 260.90 ? 502 ARG C CD  1 
ATOM   9810  N NE  . ARG C 3 479 ? 188.652 195.915 96.686  1.00 260.90 ? 502 ARG C NE  1 
ATOM   9811  C CZ  . ARG C 3 479 ? 189.488 196.045 97.710  1.00 260.90 ? 502 ARG C CZ  1 
ATOM   9812  N NH1 . ARG C 3 479 ? 189.556 195.100 98.637  1.00 260.90 ? 502 ARG C NH1 1 
ATOM   9813  N NH2 . ARG C 3 479 ? 190.257 197.121 97.808  1.00 260.90 ? 502 ARG C NH2 1 
ATOM   9814  N N   . ILE C 3 480 ? 186.116 190.521 96.282  1.00 260.41 ? 503 ILE C N   1 
ATOM   9815  C CA  . ILE C 3 480 ? 185.415 189.366 96.828  1.00 260.41 ? 503 ILE C CA  1 
ATOM   9816  C C   . ILE C 3 480 ? 185.327 189.510 98.340  1.00 260.41 ? 503 ILE C C   1 
ATOM   9817  O O   . ILE C 3 480 ? 186.309 189.872 98.998  1.00 260.41 ? 503 ILE C O   1 
ATOM   9818  C CB  . ILE C 3 480 ? 186.113 188.043 96.446  1.00 260.41 ? 503 ILE C CB  1 
ATOM   9819  C CG1 . ILE C 3 480 ? 186.346 187.978 94.935  1.00 260.41 ? 503 ILE C CG1 1 
ATOM   9820  C CG2 . ILE C 3 480 ? 185.294 186.850 96.918  1.00 260.41 ? 503 ILE C CG2 1 
ATOM   9821  C CD1 . ILE C 3 480 ? 186.717 186.600 94.429  1.00 260.41 ? 503 ILE C CD1 1 
ATOM   9822  N N   . THR C 3 481 ? 184.147 189.225 98.888  1.00 261.36 ? 504 THR C N   1 
ATOM   9823  C CA  . THR C 3 481 ? 183.934 189.258 100.328 1.00 261.36 ? 504 THR C CA  1 
ATOM   9824  C C   . THR C 3 481 ? 182.838 188.264 100.684 1.00 261.36 ? 504 THR C C   1 
ATOM   9825  O O   . THR C 3 481 ? 182.103 187.781 99.819  1.00 261.36 ? 504 THR C O   1 
ATOM   9826  C CB  . THR C 3 481 ? 183.571 190.665 100.815 1.00 261.36 ? 504 THR C CB  1 
ATOM   9827  O OG1 . THR C 3 481 ? 183.531 190.682 102.247 1.00 261.36 ? 504 THR C OG1 1 
ATOM   9828  C CG2 . THR C 3 481 ? 182.215 191.086 100.269 1.00 261.36 ? 504 THR C CG2 1 
ATOM   9829  N N   . THR C 3 482 ? 182.736 187.961 101.974 1.00 255.96 ? 505 THR C N   1 
ATOM   9830  C CA  . THR C 3 482 ? 181.748 187.020 102.483 1.00 255.96 ? 505 THR C CA  1 
ATOM   9831  C C   . THR C 3 482 ? 180.595 187.773 103.132 1.00 255.96 ? 505 THR C C   1 
ATOM   9832  O O   . THR C 3 482 ? 180.802 188.778 103.817 1.00 255.96 ? 505 THR C O   1 
ATOM   9833  C CB  . THR C 3 482 ? 182.370 186.057 103.497 1.00 255.96 ? 505 THR C CB  1 
ATOM   9834  O OG1 . THR C 3 482 ? 182.838 186.792 104.634 1.00 255.96 ? 505 THR C OG1 1 
ATOM   9835  C CG2 . THR C 3 482 ? 183.537 185.311 102.874 1.00 255.96 ? 505 THR C CG2 1 
ATOM   9836  N N   . ASN C 3 483 ? 179.379 187.279 102.911 1.00 251.25 ? 506 ASN C N   1 
ATOM   9837  C CA  . ASN C 3 483 ? 178.169 187.875 103.463 1.00 251.25 ? 506 ASN C CA  1 
ATOM   9838  C C   . ASN C 3 483 ? 177.488 186.858 104.367 1.00 251.25 ? 506 ASN C C   1 
ATOM   9839  O O   . ASN C 3 483 ? 177.165 185.750 103.926 1.00 251.25 ? 506 ASN C O   1 
ATOM   9840  C CB  . ASN C 3 483 ? 177.220 188.327 102.352 1.00 251.25 ? 506 ASN C CB  1 
ATOM   9841  C CG  . ASN C 3 483 ? 175.999 189.052 102.887 1.00 251.25 ? 506 ASN C CG  1 
ATOM   9842  O OD1 . ASN C 3 483 ? 176.016 189.587 103.996 1.00 251.25 ? 506 ASN C OD1 1 
ATOM   9843  N ND2 . ASN C 3 483 ? 174.931 189.073 102.098 1.00 251.25 ? 506 ASN C ND2 1 
ATOM   9844  N N   . ASN C 3 484 ? 177.275 187.234 105.621 1.00 243.61 ? 507 ASN C N   1 
ATOM   9845  C CA  . ASN C 3 484 ? 176.575 186.408 106.594 1.00 243.61 ? 507 ASN C CA  1 
ATOM   9846  C C   . ASN C 3 484 ? 175.318 187.144 107.061 1.00 243.61 ? 507 ASN C C   1 
ATOM   9847  O O   . ASN C 3 484 ? 174.948 188.191 106.523 1.00 243.61 ? 507 ASN C O   1 
ATOM   9848  C CB  . ASN C 3 484 ? 177.495 186.049 107.763 1.00 243.61 ? 507 ASN C CB  1 
ATOM   9849  C CG  . ASN C 3 484 ? 178.150 187.265 108.388 1.00 243.61 ? 507 ASN C CG  1 
ATOM   9850  O OD1 . ASN C 3 484 ? 177.969 188.391 107.924 1.00 243.61 ? 507 ASN C OD1 1 
ATOM   9851  N ND2 . ASN C 3 484 ? 178.914 187.043 109.451 1.00 243.61 ? 507 ASN C ND2 1 
ATOM   9852  N N   . SER C 3 485 ? 174.660 186.583 108.076 1.00 240.23 ? 508 SER C N   1 
ATOM   9853  C CA  . SER C 3 485 ? 173.426 187.159 108.598 1.00 240.23 ? 508 SER C CA  1 
ATOM   9854  C C   . SER C 3 485 ? 173.640 188.472 109.342 1.00 240.23 ? 508 SER C C   1 
ATOM   9855  O O   . SER C 3 485 ? 172.660 189.044 109.832 1.00 240.23 ? 508 SER C O   1 
ATOM   9856  C CB  . SER C 3 485 ? 172.732 186.154 109.519 1.00 240.23 ? 508 SER C CB  1 
ATOM   9857  O OG  . SER C 3 485 ? 172.733 184.856 108.952 1.00 240.23 ? 508 SER C OG  1 
ATOM   9858  N N   . MET C 3 486 ? 174.873 188.963 109.444 1.00 237.28 ? 509 MET C N   1 
ATOM   9859  C CA  . MET C 3 486 ? 175.159 190.195 110.169 1.00 237.28 ? 509 MET C CA  1 
ATOM   9860  C C   . MET C 3 486 ? 175.651 191.312 109.263 1.00 237.28 ? 509 MET C C   1 
ATOM   9861  O O   . MET C 3 486 ? 175.069 192.404 109.265 1.00 237.28 ? 509 MET C O   1 
ATOM   9862  C CB  . MET C 3 486 ? 176.191 189.926 111.276 1.00 237.28 ? 509 MET C CB  1 
ATOM   9863  C CG  . MET C 3 486 ? 175.789 188.818 112.236 1.00 237.28 ? 509 MET C CG  1 
ATOM   9864  S SD  . MET C 3 486 ? 174.170 189.094 112.980 1.00 237.28 ? 509 MET C SD  1 
ATOM   9865  C CE  . MET C 3 486 ? 174.441 190.653 113.819 1.00 237.28 ? 509 MET C CE  1 
ATOM   9866  N N   . GLY C 3 487 ? 176.705 191.076 108.486 1.00 243.91 ? 510 GLY C N   1 
ATOM   9867  C CA  . GLY C 3 487 ? 177.249 192.113 107.632 1.00 243.91 ? 510 GLY C CA  1 
ATOM   9868  C C   . GLY C 3 487 ? 178.201 191.604 106.570 1.00 243.91 ? 510 GLY C C   1 
ATOM   9869  O O   . GLY C 3 487 ? 177.991 190.530 105.998 1.00 243.91 ? 510 GLY C O   1 
ATOM   9870  N N   . ALA C 3 488 ? 179.254 192.371 106.296 1.00 250.08 ? 511 ALA C N   1 
ATOM   9871  C CA  . ALA C 3 488 ? 180.231 192.035 105.273 1.00 250.08 ? 511 ALA C CA  1 
ATOM   9872  C C   . ALA C 3 488 ? 181.622 191.935 105.885 1.00 250.08 ? 511 ALA C C   1 
ATOM   9873  O O   . ALA C 3 488 ? 181.904 192.527 106.931 1.00 250.08 ? 511 ALA C O   1 
ATOM   9874  C CB  . ALA C 3 488 ? 180.233 193.072 104.143 1.00 250.08 ? 511 ALA C CB  1 
ATOM   9875  N N   . SER C 3 489 ? 182.488 191.177 105.218 1.00 252.31 ? 512 SER C N   1 
ATOM   9876  C CA  . SER C 3 489 ? 183.862 190.957 105.640 1.00 252.31 ? 512 SER C CA  1 
ATOM   9877  C C   . SER C 3 489 ? 184.808 191.887 104.894 1.00 252.31 ? 512 SER C C   1 
ATOM   9878  O O   . SER C 3 489 ? 184.449 192.452 103.855 1.00 252.31 ? 512 SER C O   1 
ATOM   9879  C CB  . SER C 3 489 ? 184.255 189.502 105.392 1.00 252.31 ? 512 SER C CB  1 
ATOM   9880  O OG  . SER C 3 489 ? 183.832 189.071 104.110 1.00 252.31 ? 512 SER C OG  1 
ATOM   9881  N N   . PRO C 3 490 ? 186.022 192.086 105.408 1.00 248.73 ? 513 PRO C N   1 
ATOM   9882  C CA  . PRO C 3 490 ? 187.010 192.885 104.669 1.00 248.73 ? 513 PRO C CA  1 
ATOM   9883  C C   . PRO C 3 490 ? 187.301 192.278 103.304 1.00 248.73 ? 513 PRO C C   1 
ATOM   9884  O O   . PRO C 3 490 ? 187.540 191.075 103.176 1.00 248.73 ? 513 PRO C O   1 
ATOM   9885  C CB  . PRO C 3 490 ? 188.242 192.855 105.579 1.00 248.73 ? 513 PRO C CB  1 
ATOM   9886  C CG  . PRO C 3 490 ? 187.692 192.630 106.943 1.00 248.73 ? 513 PRO C CG  1 
ATOM   9887  C CD  . PRO C 3 490 ? 186.497 191.738 106.759 1.00 248.73 ? 513 PRO C CD  1 
ATOM   9888  N N   . GLU C 3 491 ? 187.279 193.126 102.281 1.00 254.84 ? 514 GLU C N   1 
ATOM   9889  C CA  . GLU C 3 491 ? 187.447 192.672 100.910 1.00 254.84 ? 514 GLU C CA  1 
ATOM   9890  C C   . GLU C 3 491 ? 188.923 192.588 100.539 1.00 254.84 ? 514 GLU C C   1 
ATOM   9891  O O   . GLU C 3 491 ? 189.764 193.323 101.065 1.00 254.84 ? 514 GLU C O   1 
ATOM   9892  C CB  . GLU C 3 491 ? 186.724 193.611 99.942  1.00 254.84 ? 514 GLU C CB  1 
ATOM   9893  C CG  . GLU C 3 491 ? 185.271 193.887 100.302 1.00 254.84 ? 514 GLU C CG  1 
ATOM   9894  C CD  . GLU C 3 491 ? 185.112 195.073 101.234 1.00 254.84 ? 514 GLU C CD  1 
ATOM   9895  O OE1 . GLU C 3 491 ? 186.111 195.783 101.472 1.00 254.84 ? 514 GLU C OE1 1 
ATOM   9896  O OE2 . GLU C 3 491 ? 183.987 195.295 101.730 1.00 254.84 ? 514 GLU C OE2 1 
ATOM   9897  N N   . SER C 3 492 ? 189.231 191.677 99.621  1.00 254.23 ? 515 SER C N   1 
ATOM   9898  C CA  . SER C 3 492 ? 190.574 191.523 99.082  1.00 254.23 ? 515 SER C CA  1 
ATOM   9899  C C   . SER C 3 492 ? 190.652 192.187 97.714  1.00 254.23 ? 515 SER C C   1 
ATOM   9900  O O   . SER C 3 492 ? 189.712 192.107 96.919  1.00 254.23 ? 515 SER C O   1 
ATOM   9901  C CB  . SER C 3 492 ? 190.955 190.045 98.973  1.00 254.23 ? 515 SER C CB  1 
ATOM   9902  O OG  . SER C 3 492 ? 190.921 189.415 100.242 1.00 254.23 ? 515 SER C OG  1 
ATOM   9903  N N   . LEU C 3 493 ? 191.778 192.841 97.444  1.00 261.18 ? 516 LEU C N   1 
ATOM   9904  C CA  . LEU C 3 493 ? 191.963 193.612 96.222  1.00 261.18 ? 516 LEU C CA  1 
ATOM   9905  C C   . LEU C 3 493 ? 192.833 192.829 95.247  1.00 261.18 ? 516 LEU C C   1 
ATOM   9906  O O   . LEU C 3 493 ? 193.941 192.408 95.596  1.00 261.18 ? 516 LEU C O   1 
ATOM   9907  C CB  . LEU C 3 493 ? 192.589 194.973 96.526  1.00 261.18 ? 516 LEU C CB  1 
ATOM   9908  C CG  . LEU C 3 493 ? 192.999 195.807 95.312  1.00 261.18 ? 516 LEU C CG  1 
ATOM   9909  C CD1 . LEU C 3 493 ? 191.799 196.549 94.750  1.00 261.18 ? 516 LEU C CD1 1 
ATOM   9910  C CD2 . LEU C 3 493 ? 194.105 196.781 95.679  1.00 261.18 ? 516 LEU C CD2 1 
ATOM   9911  N N   . MET C 3 494 ? 192.328 192.637 94.029  1.00 264.14 ? 517 MET C N   1 
ATOM   9912  C CA  . MET C 3 494 ? 193.069 191.982 92.961  1.00 264.14 ? 517 MET C CA  1 
ATOM   9913  C C   . MET C 3 494 ? 192.727 192.658 91.642  1.00 264.14 ? 517 MET C C   1 
ATOM   9914  O O   . MET C 3 494 ? 191.587 193.082 91.432  1.00 264.14 ? 517 MET C O   1 
ATOM   9915  C CB  . MET C 3 494 ? 192.749 190.484 92.886  1.00 264.14 ? 517 MET C CB  1 
ATOM   9916  C CG  . MET C 3 494 ? 193.679 189.606 93.708  1.00 264.14 ? 517 MET C CG  1 
ATOM   9917  S SD  . MET C 3 494 ? 195.370 189.594 93.084  1.00 264.14 ? 517 MET C SD  1 
ATOM   9918  C CE  . MET C 3 494 ? 196.108 188.344 94.133  1.00 264.14 ? 517 MET C CE  1 
ATOM   9919  N N   . VAL C 3 495 ? 193.717 192.754 90.757  1.00 268.45 ? 518 VAL C N   1 
ATOM   9920  C CA  . VAL C 3 495 ? 193.558 193.434 89.479  1.00 268.45 ? 518 VAL C CA  1 
ATOM   9921  C C   . VAL C 3 495 ? 194.119 192.547 88.377  1.00 268.45 ? 518 VAL C C   1 
ATOM   9922  O O   . VAL C 3 495 ? 194.983 191.697 88.614  1.00 268.45 ? 518 VAL C O   1 
ATOM   9923  C CB  . VAL C 3 495 ? 194.249 194.820 89.482  1.00 268.45 ? 518 VAL C CB  1 
ATOM   9924  C CG1 . VAL C 3 495 ? 195.763 194.670 89.417  1.00 268.45 ? 518 VAL C CG1 1 
ATOM   9925  C CG2 . VAL C 3 495 ? 193.730 195.694 88.345  1.00 268.45 ? 518 VAL C CG2 1 
ATOM   9926  N N   . LEU C 3 496 ? 193.608 192.741 87.164  1.00 273.39 ? 519 LEU C N   1 
ATOM   9927  C CA  . LEU C 3 496 ? 194.065 192.018 85.988  1.00 273.39 ? 519 LEU C CA  1 
ATOM   9928  C C   . LEU C 3 496 ? 194.888 192.943 85.101  1.00 273.39 ? 519 LEU C C   1 
ATOM   9929  O O   . LEU C 3 496 ? 194.713 194.164 85.117  1.00 273.39 ? 519 LEU C O   1 
ATOM   9930  C CB  . LEU C 3 496 ? 192.886 191.449 85.191  1.00 273.39 ? 519 LEU C CB  1 
ATOM   9931  C CG  . LEU C 3 496 ? 191.689 190.898 85.970  1.00 273.39 ? 519 LEU C CG  1 
ATOM   9932  C CD1 . LEU C 3 496 ? 190.653 190.326 85.015  1.00 273.39 ? 519 LEU C CD1 1 
ATOM   9933  C CD2 . LEU C 3 496 ? 192.127 189.845 86.974  1.00 273.39 ? 519 LEU C CD2 1 
ATOM   9934  N N   . SER C 3 497 ? 195.789 192.349 84.328  1.00 274.08 ? 520 SER C N   1 
ATOM   9935  C CA  . SER C 3 497 ? 196.651 193.081 83.413  1.00 274.08 ? 520 SER C CA  1 
ATOM   9936  C C   . SER C 3 497 ? 196.403 192.616 81.981  1.00 274.08 ? 520 SER C C   1 
ATOM   9937  O O   . SER C 3 497 ? 195.533 191.783 81.711  1.00 274.08 ? 520 SER C O   1 
ATOM   9938  C CB  . SER C 3 497 ? 198.121 192.909 83.804  1.00 274.08 ? 520 SER C CB  1 
ATOM   9939  O OG  . SER C 3 497 ? 198.682 191.765 83.186  1.00 274.08 ? 520 SER C OG  1 
ATOM   9940  N N   . ASN C 3 498 ? 197.185 193.167 81.056  1.00 272.45 ? 521 ASN C N   1 
ATOM   9941  C CA  . ASN C 3 498 ? 197.060 192.849 79.640  1.00 272.45 ? 521 ASN C CA  1 
ATOM   9942  C C   . ASN C 3 498 ? 197.803 191.577 79.246  1.00 272.45 ? 521 ASN C C   1 
ATOM   9943  O O   . ASN C 3 498 ? 197.876 191.268 78.052  1.00 272.45 ? 521 ASN C O   1 
ATOM   9944  C CB  . ASN C 3 498 ? 197.559 194.023 78.792  1.00 272.45 ? 521 ASN C CB  1 
ATOM   9945  C CG  . ASN C 3 498 ? 198.990 194.406 79.114  1.00 272.45 ? 521 ASN C CG  1 
ATOM   9946  O OD1 . ASN C 3 498 ? 199.243 195.205 80.015  1.00 272.45 ? 521 ASN C OD1 1 
ATOM   9947  N ND2 . ASN C 3 498 ? 199.936 193.836 78.376  1.00 272.45 ? 521 ASN C ND2 1 
ATOM   9948  N N   . ASP C 3 499 ? 198.352 190.840 80.208  1.00 275.95 ? 522 ASP C N   1 
ATOM   9949  C CA  . ASP C 3 499 ? 199.068 189.612 79.902  1.00 275.95 ? 522 ASP C CA  1 
ATOM   9950  C C   . ASP C 3 499 ? 198.090 188.494 79.564  1.00 275.95 ? 522 ASP C C   1 
ATOM   9951  O O   . ASP C 3 499 ? 197.038 188.356 80.193  1.00 275.95 ? 522 ASP C O   1 
ATOM   9952  C CB  . ASP C 3 499 ? 199.954 189.198 81.078  1.00 275.95 ? 522 ASP C CB  1 
ATOM   9953  C CG  . ASP C 3 499 ? 199.157 188.889 82.330  1.00 275.95 ? 522 ASP C CG  1 
ATOM   9954  O OD1 . ASP C 3 499 ? 198.124 189.552 82.559  1.00 275.95 ? 522 ASP C OD1 1 
ATOM   9955  O OD2 . ASP C 3 499 ? 199.564 187.982 83.086  1.00 275.95 ? 522 ASP C OD2 1 
ATOM   9956  N N   . SER C 3 500 ? 198.443 187.698 78.556  1.00 284.31 ? 523 SER C N   1 
ATOM   9957  C CA  . SER C 3 500 ? 197.616 186.578 78.131  1.00 284.31 ? 523 SER C CA  1 
ATOM   9958  C C   . SER C 3 500 ? 197.908 185.296 78.897  1.00 284.31 ? 523 SER C C   1 
ATOM   9959  O O   . SER C 3 500 ? 197.211 184.297 78.690  1.00 284.31 ? 523 SER C O   1 
ATOM   9960  C CB  . SER C 3 500 ? 197.799 186.326 76.630  1.00 284.31 ? 523 SER C CB  1 
ATOM   9961  O OG  . SER C 3 500 ? 198.898 185.466 76.388  1.00 284.31 ? 523 SER C OG  1 
ATOM   9962  N N   . GLY C 3 501 ? 198.912 185.297 79.771  1.00 285.07 ? 524 GLY C N   1 
ATOM   9963  C CA  . GLY C 3 501 ? 199.283 184.114 80.516  1.00 285.07 ? 524 GLY C CA  1 
ATOM   9964  C C   . GLY C 3 501 ? 200.219 183.170 79.796  1.00 285.07 ? 524 GLY C C   1 
ATOM   9965  O O   . GLY C 3 501 ? 200.578 182.130 80.363  1.00 285.07 ? 524 GLY C O   1 
ATOM   9966  N N   . HIS C 3 502 ? 200.628 183.495 78.569  1.00 290.14 ? 525 HIS C N   1 
ATOM   9967  C CA  . HIS C 3 502 ? 201.528 182.658 77.786  1.00 290.14 ? 525 HIS C CA  1 
ATOM   9968  C C   . HIS C 3 502 ? 202.940 183.231 77.722  1.00 290.14 ? 525 HIS C C   1 
ATOM   9969  O O   . HIS C 3 502 ? 203.624 183.084 76.702  1.00 290.14 ? 525 HIS C O   1 
ATOM   9970  C CB  . HIS C 3 502 ? 200.972 182.457 76.376  1.00 290.14 ? 525 HIS C CB  1 
ATOM   9971  C CG  . HIS C 3 502 ? 199.547 181.998 76.348  1.00 290.14 ? 525 HIS C CG  1 
ATOM   9972  N ND1 . HIS C 3 502 ? 198.483 182.864 76.474  1.00 290.14 ? 525 HIS C ND1 1 
ATOM   9973  C CD2 . HIS C 3 502 ? 199.012 180.761 76.210  1.00 290.14 ? 525 HIS C CD2 1 
ATOM   9974  C CE1 . HIS C 3 502 ? 197.353 182.181 76.413  1.00 290.14 ? 525 HIS C CE1 1 
ATOM   9975  N NE2 . HIS C 3 502 ? 197.646 180.903 76.253  1.00 290.14 ? 525 HIS C NE2 1 
ATOM   9976  N N   . GLU C 3 503 ? 203.389 183.885 78.790  1.00 289.65 ? 526 GLU C N   1 
ATOM   9977  C CA  . GLU C 3 503 ? 204.732 184.449 78.814  1.00 289.65 ? 526 GLU C CA  1 
ATOM   9978  C C   . GLU C 3 503 ? 205.770 183.334 78.844  1.00 289.65 ? 526 GLU C C   1 
ATOM   9979  O O   . GLU C 3 503 ? 205.740 182.464 79.721  1.00 289.65 ? 526 GLU C O   1 
ATOM   9980  C CB  . GLU C 3 503 ? 204.902 185.366 80.024  1.00 289.65 ? 526 GLU C CB  1 
ATOM   9981  C CG  . GLU C 3 503 ? 203.876 186.486 80.105  1.00 289.65 ? 526 GLU C CG  1 
ATOM   9982  C CD  . GLU C 3 503 ? 204.193 187.490 81.196  1.00 289.65 ? 526 GLU C CD  1 
ATOM   9983  O OE1 . GLU C 3 503 ? 205.391 187.735 81.451  1.00 289.65 ? 526 GLU C OE1 1 
ATOM   9984  O OE2 . GLU C 3 503 ? 203.244 188.036 81.798  1.00 289.65 ? 526 GLU C OE2 1 
ATOM   9985  N N   . GLU C 3 504 ? 206.690 183.361 77.883  1.00 290.19 ? 527 GLU C N   1 
ATOM   9986  C CA  . GLU C 3 504 ? 207.710 182.325 77.758  1.00 290.19 ? 527 GLU C CA  1 
ATOM   9987  C C   . GLU C 3 504 ? 208.808 182.575 78.784  1.00 290.19 ? 527 GLU C C   1 
ATOM   9988  O O   . GLU C 3 504 ? 209.595 183.518 78.647  1.00 290.19 ? 527 GLU C O   1 
ATOM   9989  C CB  . GLU C 3 504 ? 208.276 182.302 76.341  1.00 290.19 ? 527 GLU C CB  1 
ATOM   9990  C CG  . GLU C 3 504 ? 209.161 181.101 76.041  1.00 290.19 ? 527 GLU C CG  1 
ATOM   9991  C CD  . GLU C 3 504 ? 208.609 179.807 76.608  1.00 290.19 ? 527 GLU C CD  1 
ATOM   9992  O OE1 . GLU C 3 504 ? 209.334 179.133 77.370  1.00 290.19 ? 527 GLU C OE1 1 
ATOM   9993  O OE2 . GLU C 3 504 ? 207.453 179.458 76.285  1.00 290.19 ? 527 GLU C OE2 1 
ATOM   9994  N N   . VAL C 3 505 ? 208.862 181.732 79.813  1.00 284.54 ? 528 VAL C N   1 
ATOM   9995  C CA  . VAL C 3 505 ? 209.889 181.804 80.841  1.00 284.54 ? 528 VAL C CA  1 
ATOM   9996  C C   . VAL C 3 505 ? 210.681 180.501 80.822  1.00 284.54 ? 528 VAL C C   1 
ATOM   9997  O O   . VAL C 3 505 ? 210.383 179.575 80.067  1.00 284.54 ? 528 VAL C O   1 
ATOM   9998  C CB  . VAL C 3 505 ? 209.302 182.071 82.240  1.00 284.54 ? 528 VAL C CB  1 
ATOM   9999  C CG1 . VAL C 3 505 ? 208.830 183.513 82.349  1.00 284.54 ? 528 VAL C CG1 1 
ATOM   10000 C CG2 . VAL C 3 505 ? 208.162 181.106 82.529  1.00 284.54 ? 528 VAL C CG2 1 
ATOM   10001 N N   . LYS C 3 506 ? 211.704 180.440 81.670  1.00 279.91 ? 529 LYS C N   1 
ATOM   10002 C CA  . LYS C 3 506 ? 212.555 179.261 81.738  1.00 279.91 ? 529 LYS C CA  1 
ATOM   10003 C C   . LYS C 3 506 ? 211.879 178.159 82.544  1.00 279.91 ? 529 LYS C C   1 
ATOM   10004 O O   . LYS C 3 506 ? 211.185 178.423 83.530  1.00 279.91 ? 529 LYS C O   1 
ATOM   10005 C CB  . LYS C 3 506 ? 213.916 179.618 82.344  1.00 279.91 ? 529 LYS C CB  1 
ATOM   10006 C CG  . LYS C 3 506 ? 213.879 180.168 83.768  1.00 279.91 ? 529 LYS C CG  1 
ATOM   10007 C CD  . LYS C 3 506 ? 214.093 179.076 84.809  1.00 279.91 ? 529 LYS C CD  1 
ATOM   10008 C CE  . LYS C 3 506 ? 214.303 179.665 86.194  1.00 279.91 ? 529 LYS C CE  1 
ATOM   10009 N NZ  . LYS C 3 506 ? 214.571 178.612 87.212  1.00 279.91 ? 529 LYS C NZ  1 
ATOM   10010 N N   . GLU C 3 507 ? 212.081 176.918 82.111  1.00 278.70 ? 530 GLU C N   1 
ATOM   10011 C CA  . GLU C 3 507 ? 211.515 175.749 82.771  1.00 278.70 ? 530 GLU C CA  1 
ATOM   10012 C C   . GLU C 3 507 ? 212.610 175.048 83.564  1.00 278.70 ? 530 GLU C C   1 
ATOM   10013 O O   . GLU C 3 507 ? 213.642 174.665 83.002  1.00 278.70 ? 530 GLU C O   1 
ATOM   10014 C CB  . GLU C 3 507 ? 210.891 174.796 81.751  1.00 278.70 ? 530 GLU C CB  1 
ATOM   10015 C CG  . GLU C 3 507 ? 209.919 175.464 80.793  1.00 278.70 ? 530 GLU C CG  1 
ATOM   10016 C CD  . GLU C 3 507 ? 208.690 176.009 81.494  1.00 278.70 ? 530 GLU C CD  1 
ATOM   10017 O OE1 . GLU C 3 507 ? 208.159 175.317 82.388  1.00 278.70 ? 530 GLU C OE1 1 
ATOM   10018 O OE2 . GLU C 3 507 ? 208.255 177.128 81.152  1.00 278.70 ? 530 GLU C OE2 1 
ATOM   10019 N N   . LYS C 3 508 ? 212.384 174.880 84.865  1.00 273.66 ? 531 LYS C N   1 
ATOM   10020 C CA  . LYS C 3 508 ? 213.342 174.243 85.758  1.00 273.66 ? 531 LYS C CA  1 
ATOM   10021 C C   . LYS C 3 508 ? 212.716 172.991 86.353  1.00 273.66 ? 531 LYS C C   1 
ATOM   10022 O O   . LYS C 3 508 ? 211.585 173.031 86.847  1.00 273.66 ? 531 LYS C O   1 
ATOM   10023 C CB  . LYS C 3 508 ? 213.780 175.201 86.871  1.00 273.66 ? 531 LYS C CB  1 
ATOM   10024 C CG  . LYS C 3 508 ? 215.183 174.943 87.401  1.00 273.66 ? 531 LYS C CG  1 
ATOM   10025 C CD  . LYS C 3 508 ? 215.175 173.913 88.519  1.00 273.66 ? 531 LYS C CD  1 
ATOM   10026 C CE  . LYS C 3 508 ? 216.579 173.645 89.035  1.00 273.66 ? 531 LYS C CE  1 
ATOM   10027 N NZ  . LYS C 3 508 ? 216.585 172.619 90.114  1.00 273.66 ? 531 LYS C NZ  1 
ATOM   10028 N N   . THR C 3 509 ? 213.454 171.886 86.305  1.00 271.17 ? 532 THR C N   1 
ATOM   10029 C CA  . THR C 3 509 ? 213.005 170.614 86.854  1.00 271.17 ? 532 THR C CA  1 
ATOM   10030 C C   . THR C 3 509 ? 213.658 170.390 88.211  1.00 271.17 ? 532 THR C C   1 
ATOM   10031 O O   . THR C 3 509 ? 214.885 170.465 88.334  1.00 271.17 ? 532 THR C O   1 
ATOM   10032 C CB  . THR C 3 509 ? 213.343 169.460 85.909  1.00 271.17 ? 532 THR C CB  1 
ATOM   10033 O OG1 . THR C 3 509 ? 214.679 169.620 85.415  1.00 271.17 ? 532 THR C OG1 1 
ATOM   10034 C CG2 . THR C 3 509 ? 212.376 169.434 84.735  1.00 271.17 ? 532 THR C CG2 1 
ATOM   10035 N N   . ILE C 3 510 ? 212.839 170.117 89.222  1.00 273.16 ? 533 ILE C N   1 
ATOM   10036 C CA  . ILE C 3 510 ? 213.315 169.910 90.582  1.00 273.16 ? 533 ILE C CA  1 
ATOM   10037 C C   . ILE C 3 510 ? 212.979 168.491 91.016  1.00 273.16 ? 533 ILE C C   1 
ATOM   10038 O O   . ILE C 3 510 ? 212.025 167.877 90.527  1.00 273.16 ? 533 ILE C O   1 
ATOM   10039 C CB  . ILE C 3 510 ? 212.711 170.936 91.566  1.00 273.16 ? 533 ILE C CB  1 
ATOM   10040 C CG1 . ILE C 3 510 ? 211.182 170.872 91.533  1.00 273.16 ? 533 ILE C CG1 1 
ATOM   10041 C CG2 . ILE C 3 510 ? 213.197 172.339 91.238  1.00 273.16 ? 533 ILE C CG2 1 
ATOM   10042 C CD1 . ILE C 3 510 ? 210.509 171.862 92.458  1.00 273.16 ? 533 ILE C CD1 1 
ATOM   10043 N N   . LYS C 3 511 ? 213.780 167.969 91.943  1.00 273.71 ? 534 LYS C N   1 
ATOM   10044 C CA  . LYS C 3 511 ? 213.560 166.650 92.526  1.00 273.71 ? 534 LYS C CA  1 
ATOM   10045 C C   . LYS C 3 511 ? 212.895 166.840 93.884  1.00 273.71 ? 534 LYS C C   1 
ATOM   10046 O O   . LYS C 3 511 ? 213.543 167.259 94.849  1.00 273.71 ? 534 LYS C O   1 
ATOM   10047 C CB  . LYS C 3 511 ? 214.874 165.883 92.657  1.00 273.71 ? 534 LYS C CB  1 
ATOM   10048 C CG  . LYS C 3 511 ? 214.706 164.439 93.098  1.00 273.71 ? 534 LYS C CG  1 
ATOM   10049 C CD  . LYS C 3 511 ? 213.877 163.650 92.097  1.00 273.71 ? 534 LYS C CD  1 
ATOM   10050 C CE  . LYS C 3 511 ? 213.591 162.245 92.601  1.00 273.71 ? 534 LYS C CE  1 
ATOM   10051 N NZ  . LYS C 3 511 ? 212.778 162.258 93.848  1.00 273.71 ? 534 LYS C NZ  1 
ATOM   10052 N N   . GLY C 3 512 ? 211.601 166.532 93.957  1.00 273.16 ? 535 GLY C N   1 
ATOM   10053 C CA  . GLY C 3 512 ? 210.843 166.778 95.164  1.00 273.16 ? 535 GLY C CA  1 
ATOM   10054 C C   . GLY C 3 512 ? 211.100 165.759 96.257  1.00 273.16 ? 535 GLY C C   1 
ATOM   10055 O O   . GLY C 3 512 ? 211.603 164.659 96.031  1.00 273.16 ? 535 GLY C O   1 
ATOM   10056 N N   . ILE C 3 513 ? 210.738 166.152 97.473  1.00 270.85 ? 536 ILE C N   1 
ATOM   10057 C CA  . ILE C 3 513 ? 210.843 165.296 98.640  1.00 270.85 ? 536 ILE C CA  1 
ATOM   10058 C C   . ILE C 3 513 ? 209.512 164.575 98.817  1.00 270.85 ? 536 ILE C C   1 
ATOM   10059 O O   . ILE C 3 513 ? 208.479 164.981 98.276  1.00 270.85 ? 536 ILE C O   1 
ATOM   10060 C CB  . ILE C 3 513 ? 211.234 166.103 99.905  1.00 270.85 ? 536 ILE C CB  1 
ATOM   10061 C CG1 . ILE C 3 513 ? 212.393 167.054 99.594  1.00 270.85 ? 536 ILE C CG1 1 
ATOM   10062 C CG2 . ILE C 3 513 ? 211.651 165.184 101.043 1.00 270.85 ? 536 ILE C CG2 1 
ATOM   10063 C CD1 . ILE C 3 513 ? 211.977 168.490 99.347  1.00 270.85 ? 536 ILE C CD1 1 
ATOM   10064 N N   . LYS C 3 514 ? 209.539 163.470 99.571  1.00 268.20 ? 537 LYS C N   1 
ATOM   10065 C CA  . LYS C 3 514 ? 208.347 162.645 99.748  1.00 268.20 ? 537 LYS C CA  1 
ATOM   10066 C C   . LYS C 3 514 ? 207.165 163.441 100.290 1.00 268.20 ? 537 LYS C C   1 
ATOM   10067 O O   . LYS C 3 514 ? 206.011 163.126 99.979  1.00 268.20 ? 537 LYS C O   1 
ATOM   10068 C CB  . LYS C 3 514 ? 208.660 161.465 100.673 1.00 268.20 ? 537 LYS C CB  1 
ATOM   10069 C CG  . LYS C 3 514 ? 209.031 161.858 102.095 1.00 268.20 ? 537 LYS C CG  1 
ATOM   10070 C CD  . LYS C 3 514 ? 209.834 160.766 102.781 1.00 268.20 ? 537 LYS C CD  1 
ATOM   10071 C CE  . LYS C 3 514 ? 211.239 160.672 102.211 1.00 268.20 ? 537 LYS C CE  1 
ATOM   10072 N NZ  . LYS C 3 514 ? 211.933 161.989 102.230 1.00 268.20 ? 537 LYS C NZ  1 
ATOM   10073 N N   . ASP C 3 515 ? 207.426 164.473 101.098 1.00 267.05 ? 538 ASP C N   1 
ATOM   10074 C CA  . ASP C 3 515 ? 206.355 165.304 101.635 1.00 267.05 ? 538 ASP C CA  1 
ATOM   10075 C C   . ASP C 3 515 ? 206.728 166.782 101.606 1.00 267.05 ? 538 ASP C C   1 
ATOM   10076 O O   . ASP C 3 515 ? 206.244 167.564 102.432 1.00 267.05 ? 538 ASP C O   1 
ATOM   10077 C CB  . ASP C 3 515 ? 205.994 164.882 103.061 1.00 267.05 ? 538 ASP C CB  1 
ATOM   10078 C CG  . ASP C 3 515 ? 204.554 165.198 103.415 1.00 267.05 ? 538 ASP C CG  1 
ATOM   10079 O OD1 . ASP C 3 515 ? 203.820 165.696 102.535 1.00 267.05 ? 538 ASP C OD1 1 
ATOM   10080 O OD2 . ASP C 3 515 ? 204.155 164.948 104.572 1.00 267.05 ? 538 ASP C OD2 1 
ATOM   10081 N N   . ALA C 3 516 ? 207.580 167.182 100.665 1.00 268.56 ? 539 ALA C N   1 
ATOM   10082 C CA  . ALA C 3 516 ? 207.999 168.571 100.554 1.00 268.56 ? 539 ALA C CA  1 
ATOM   10083 C C   . ALA C 3 516 ? 208.527 168.816 99.148  1.00 268.56 ? 539 ALA C C   1 
ATOM   10084 O O   . ALA C 3 516 ? 208.729 167.881 98.369  1.00 268.56 ? 539 ALA C O   1 
ATOM   10085 C CB  . ALA C 3 516 ? 209.062 168.926 101.600 1.00 268.56 ? 539 ALA C CB  1 
ATOM   10086 N N   . PHE C 3 517 ? 208.748 170.091 98.836  1.00 272.05 ? 540 PHE C N   1 
ATOM   10087 C CA  . PHE C 3 517 ? 209.274 170.497 97.542  1.00 272.05 ? 540 PHE C CA  1 
ATOM   10088 C C   . PHE C 3 517 ? 210.209 171.682 97.728  1.00 272.05 ? 540 PHE C C   1 
ATOM   10089 O O   . PHE C 3 517 ? 209.943 172.570 98.542  1.00 272.05 ? 540 PHE C O   1 
ATOM   10090 C CB  . PHE C 3 517 ? 208.148 170.863 96.567  1.00 272.05 ? 540 PHE C CB  1 
ATOM   10091 C CG  . PHE C 3 517 ? 207.636 169.699 95.768  1.00 272.05 ? 540 PHE C CG  1 
ATOM   10092 C CD1 . PHE C 3 517 ? 208.232 169.351 94.567  1.00 272.05 ? 540 PHE C CD1 1 
ATOM   10093 C CD2 . PHE C 3 517 ? 206.561 168.951 96.219  1.00 272.05 ? 540 PHE C CD2 1 
ATOM   10094 C CE1 . PHE C 3 517 ? 207.763 168.280 93.829  1.00 272.05 ? 540 PHE C CE1 1 
ATOM   10095 C CE2 . PHE C 3 517 ? 206.088 167.879 95.486  1.00 272.05 ? 540 PHE C CE2 1 
ATOM   10096 C CZ  . PHE C 3 517 ? 206.690 167.544 94.289  1.00 272.05 ? 540 PHE C CZ  1 
ATOM   10097 N N   . ASN C 3 518 ? 211.302 171.688 96.969  1.00 271.62 ? 541 ASN C N   1 
ATOM   10098 C CA  . ASN C 3 518 ? 212.306 172.750 97.036  1.00 271.62 ? 541 ASN C CA  1 
ATOM   10099 C C   . ASN C 3 518 ? 212.017 173.746 95.916  1.00 271.62 ? 541 ASN C C   1 
ATOM   10100 O O   . ASN C 3 518 ? 212.617 173.696 94.842  1.00 271.62 ? 541 ASN C O   1 
ATOM   10101 C CB  . ASN C 3 518 ? 213.713 172.173 96.935  1.00 271.62 ? 541 ASN C CB  1 
ATOM   10102 C CG  . ASN C 3 518 ? 213.831 171.103 95.866  1.00 271.62 ? 541 ASN C CG  1 
ATOM   10103 O OD1 . ASN C 3 518 ? 212.871 170.815 95.151  1.00 271.62 ? 541 ASN C OD1 1 
ATOM   10104 N ND2 . ASN C 3 518 ? 215.013 170.509 95.751  1.00 271.62 ? 541 ASN C ND2 1 
ATOM   10105 N N   . ILE C 3 519 ? 211.090 174.662 96.177  1.00 273.17 ? 542 ILE C N   1 
ATOM   10106 C CA  . ILE C 3 519 ? 210.702 175.690 95.219  1.00 273.17 ? 542 ILE C CA  1 
ATOM   10107 C C   . ILE C 3 519 ? 211.584 176.909 95.448  1.00 273.17 ? 542 ILE C C   1 
ATOM   10108 O O   . ILE C 3 519 ? 211.601 177.476 96.548  1.00 273.17 ? 542 ILE C O   1 
ATOM   10109 C CB  . ILE C 3 519 ? 209.214 176.050 95.351  1.00 273.17 ? 542 ILE C CB  1 
ATOM   10110 C CG1 . ILE C 3 519 ? 208.342 174.826 95.061  1.00 273.17 ? 542 ILE C CG1 1 
ATOM   10111 C CG2 . ILE C 3 519 ? 208.858 177.196 94.415  1.00 273.17 ? 542 ILE C CG2 1 
ATOM   10112 C CD1 . ILE C 3 519 ? 206.856 175.098 95.157  1.00 273.17 ? 542 ILE C CD1 1 
ATOM   10113 N N   . SER C 3 520 ? 212.316 177.314 94.413  1.00 273.49 ? 543 SER C N   1 
ATOM   10114 C CA  . SER C 3 520 ? 213.214 178.461 94.492  1.00 273.49 ? 543 SER C CA  1 
ATOM   10115 C C   . SER C 3 520 ? 212.977 179.349 93.281  1.00 273.49 ? 543 SER C C   1 
ATOM   10116 O O   . SER C 3 520 ? 213.137 178.902 92.142  1.00 273.49 ? 543 SER C O   1 
ATOM   10117 C CB  . SER C 3 520 ? 214.678 178.017 94.554  1.00 273.49 ? 543 SER C CB  1 
ATOM   10118 O OG  . SER C 3 520 ? 215.545 179.063 94.152  1.00 273.49 ? 543 SER C OG  1 
ATOM   10119 N N   . TRP C 3 521 ? 212.600 180.601 93.528  1.00 275.54 ? 544 TRP C N   1 
ATOM   10120 C CA  . TRP C 3 521 ? 212.343 181.568 92.473  1.00 275.54 ? 544 TRP C CA  1 
ATOM   10121 C C   . TRP C 3 521 ? 213.300 182.745 92.605  1.00 275.54 ? 544 TRP C C   1 
ATOM   10122 O O   . TRP C 3 521 ? 213.662 183.153 93.713  1.00 275.54 ? 544 TRP C O   1 
ATOM   10123 C CB  . TRP C 3 521 ? 210.893 182.067 92.513  1.00 275.54 ? 544 TRP C CB  1 
ATOM   10124 C CG  . TRP C 3 521 ? 210.526 182.756 93.792  1.00 275.54 ? 544 TRP C CG  1 
ATOM   10125 C CD1 . TRP C 3 521 ? 210.559 184.098 94.039  1.00 275.54 ? 544 TRP C CD1 1 
ATOM   10126 C CD2 . TRP C 3 521 ? 210.067 182.138 95.001  1.00 275.54 ? 544 TRP C CD2 1 
ATOM   10127 N NE1 . TRP C 3 521 ? 210.150 184.353 95.325  1.00 275.54 ? 544 TRP C NE1 1 
ATOM   10128 C CE2 . TRP C 3 521 ? 209.843 183.167 95.937  1.00 275.54 ? 544 TRP C CE2 1 
ATOM   10129 C CE3 . TRP C 3 521 ? 209.825 180.815 95.382  1.00 275.54 ? 544 TRP C CE3 1 
ATOM   10130 C CZ2 . TRP C 3 521 ? 209.389 182.914 97.230  1.00 275.54 ? 544 TRP C CZ2 1 
ATOM   10131 C CZ3 . TRP C 3 521 ? 209.374 180.566 96.666  1.00 275.54 ? 544 TRP C CZ3 1 
ATOM   10132 C CH2 . TRP C 3 521 ? 209.161 181.610 97.574  1.00 275.54 ? 544 TRP C CH2 1 
ATOM   10133 N N   . GLU C 3 522 ? 213.706 183.288 91.460  1.00 275.63 ? 545 GLU C N   1 
ATOM   10134 C CA  . GLU C 3 522 ? 214.632 184.415 91.442  1.00 275.63 ? 545 GLU C CA  1 
ATOM   10135 C C   . GLU C 3 522 ? 213.858 185.724 91.347  1.00 275.63 ? 545 GLU C C   1 
ATOM   10136 O O   . GLU C 3 522 ? 213.022 185.876 90.449  1.00 275.63 ? 545 GLU C O   1 
ATOM   10137 C CB  . GLU C 3 522 ? 215.601 184.304 90.273  1.00 275.63 ? 545 GLU C CB  1 
ATOM   10138 C CG  . GLU C 3 522 ? 216.813 183.422 90.542  1.00 275.63 ? 545 GLU C CG  1 
ATOM   10139 C CD  . GLU C 3 522 ? 216.436 181.992 90.882  1.00 275.63 ? 545 GLU C CD  1 
ATOM   10140 O OE1 . GLU C 3 522 ? 215.794 181.330 90.040  1.00 275.63 ? 545 GLU C OE1 1 
ATOM   10141 O OE2 . GLU C 3 522 ? 216.782 181.531 91.990  1.00 275.63 ? 545 GLU C OE2 1 
ATOM   10142 N N   . PRO C 3 523 ? 214.099 186.677 92.246  1.00 270.95 ? 546 PRO C N   1 
ATOM   10143 C CA  . PRO C 3 523 ? 213.369 187.949 92.181  1.00 270.95 ? 546 PRO C CA  1 
ATOM   10144 C C   . PRO C 3 523 ? 213.759 188.752 90.951  1.00 270.95 ? 546 PRO C C   1 
ATOM   10145 O O   . PRO C 3 523 ? 214.928 188.798 90.558  1.00 270.95 ? 546 PRO C O   1 
ATOM   10146 C CB  . PRO C 3 523 ? 213.783 188.667 93.473  1.00 270.95 ? 546 PRO C CB  1 
ATOM   10147 C CG  . PRO C 3 523 ? 214.381 187.601 94.348  1.00 270.95 ? 546 PRO C CG  1 
ATOM   10148 C CD  . PRO C 3 523 ? 214.993 186.610 93.413  1.00 270.95 ? 546 PRO C CD  1 
ATOM   10149 N N   . VAL C 3 524 ? 212.763 189.389 90.342  1.00 269.26 ? 547 VAL C N   1 
ATOM   10150 C CA  . VAL C 3 524 ? 212.984 190.214 89.162  1.00 269.26 ? 547 VAL C CA  1 
ATOM   10151 C C   . VAL C 3 524 ? 212.813 191.703 89.448  1.00 269.26 ? 547 VAL C C   1 
ATOM   10152 O O   . VAL C 3 524 ? 213.419 192.525 88.741  1.00 269.26 ? 547 VAL C O   1 
ATOM   10153 C CB  . VAL C 3 524 ? 212.063 189.778 88.001  1.00 269.26 ? 547 VAL C CB  1 
ATOM   10154 C CG1 . VAL C 3 524 ? 210.605 190.073 88.327  1.00 269.26 ? 547 VAL C CG1 1 
ATOM   10155 C CG2 . VAL C 3 524 ? 212.482 190.434 86.687  1.00 269.26 ? 547 VAL C CG2 1 
ATOM   10156 N N   . SER C 3 525 ? 212.041 192.078 90.464  1.00 268.23 ? 548 SER C N   1 
ATOM   10157 C CA  . SER C 3 525 ? 211.820 193.471 90.814  1.00 268.23 ? 548 SER C CA  1 
ATOM   10158 C C   . SER C 3 525 ? 212.197 193.707 92.270  1.00 268.23 ? 548 SER C C   1 
ATOM   10159 O O   . SER C 3 525 ? 212.256 192.776 93.079  1.00 268.23 ? 548 SER C O   1 
ATOM   10160 C CB  . SER C 3 525 ? 210.360 193.880 90.577  1.00 268.23 ? 548 SER C CB  1 
ATOM   10161 O OG  . SER C 3 525 ? 209.893 193.399 89.329  1.00 268.23 ? 548 SER C OG  1 
ATOM   10162 N N   . GLY C 3 526 ? 212.454 194.971 92.597  1.00 264.99 ? 549 GLY C N   1 
ATOM   10163 C CA  . GLY C 3 526 ? 212.844 195.338 93.943  1.00 264.99 ? 549 GLY C CA  1 
ATOM   10164 C C   . GLY C 3 526 ? 211.712 195.925 94.760  1.00 264.99 ? 549 GLY C C   1 
ATOM   10165 O O   . GLY C 3 526 ? 211.864 196.161 95.963  1.00 264.99 ? 549 GLY C O   1 
ATOM   10166 N N   . ASP C 3 527 ? 210.571 196.166 94.120  1.00 263.09 ? 550 ASP C N   1 
ATOM   10167 C CA  . ASP C 3 527 ? 209.391 196.733 94.770  1.00 263.09 ? 550 ASP C CA  1 
ATOM   10168 C C   . ASP C 3 527 ? 208.231 195.761 94.566  1.00 263.09 ? 550 ASP C C   1 
ATOM   10169 O O   . ASP C 3 527 ? 207.483 195.865 93.591  1.00 263.09 ? 550 ASP C O   1 
ATOM   10170 C CB  . ASP C 3 527 ? 209.069 198.121 94.215  1.00 263.09 ? 550 ASP C CB  1 
ATOM   10171 C CG  . ASP C 3 527 ? 209.617 199.237 95.084  1.00 263.09 ? 550 ASP C CG  1 
ATOM   10172 O OD1 . ASP C 3 527 ? 210.373 198.938 96.033  1.00 263.09 ? 550 ASP C OD1 1 
ATOM   10173 O OD2 . ASP C 3 527 ? 209.292 200.413 94.819  1.00 263.09 ? 550 ASP C OD2 1 
ATOM   10174 N N   . THR C 3 528 ? 208.087 194.816 95.491  1.00 265.80 ? 551 THR C N   1 
ATOM   10175 C CA  . THR C 3 528 ? 207.032 193.816 95.432  1.00 265.80 ? 551 THR C CA  1 
ATOM   10176 C C   . THR C 3 528 ? 206.388 193.671 96.804  1.00 265.80 ? 551 THR C C   1 
ATOM   10177 O O   . THR C 3 528 ? 206.938 194.097 97.822  1.00 265.80 ? 551 THR C O   1 
ATOM   10178 C CB  . THR C 3 528 ? 207.566 192.455 94.960  1.00 265.80 ? 551 THR C CB  1 
ATOM   10179 O OG1 . THR C 3 528 ? 206.519 191.479 95.031  1.00 265.80 ? 551 THR C OG1 1 
ATOM   10180 C CG2 . THR C 3 528 ? 208.730 192.008 95.831  1.00 265.80 ? 551 THR C CG2 1 
ATOM   10181 N N   . MET C 3 529 ? 205.204 193.058 96.816  1.00 263.55 ? 552 MET C N   1 
ATOM   10182 C CA  . MET C 3 529 ? 204.461 192.832 98.046  1.00 263.55 ? 552 MET C CA  1 
ATOM   10183 C C   . MET C 3 529 ? 204.376 191.366 98.445  1.00 263.55 ? 552 MET C C   1 
ATOM   10184 O O   . MET C 3 529 ? 203.977 191.074 99.577  1.00 263.55 ? 552 MET C O   1 
ATOM   10185 C CB  . MET C 3 529 ? 203.039 193.400 97.922  1.00 263.55 ? 552 MET C CB  1 
ATOM   10186 C CG  . MET C 3 529 ? 202.988 194.890 97.629  1.00 263.55 ? 552 MET C CG  1 
ATOM   10187 S SD  . MET C 3 529 ? 201.363 195.597 97.958  1.00 263.55 ? 552 MET C SD  1 
ATOM   10188 C CE  . MET C 3 529 ? 200.306 194.380 97.178  1.00 263.55 ? 552 MET C CE  1 
ATOM   10189 N N   . GLY C 3 530 ? 204.731 190.448 97.561  1.00 268.23 ? 553 GLY C N   1 
ATOM   10190 C CA  . GLY C 3 530 ? 204.685 189.038 97.886  1.00 268.23 ? 553 GLY C CA  1 
ATOM   10191 C C   . GLY C 3 530 ? 204.611 188.195 96.633  1.00 268.23 ? 553 GLY C C   1 
ATOM   10192 O O   . GLY C 3 530 ? 204.492 188.699 95.516  1.00 268.23 ? 553 GLY C O   1 
ATOM   10193 N N   . TYR C 3 531 ? 204.683 186.885 96.849  1.00 270.61 ? 554 TYR C N   1 
ATOM   10194 C CA  . TYR C 3 531 ? 204.625 185.904 95.777  1.00 270.61 ? 554 TYR C CA  1 
ATOM   10195 C C   . TYR C 3 531 ? 203.480 184.932 96.025  1.00 270.61 ? 554 TYR C C   1 
ATOM   10196 O O   . TYR C 3 531 ? 203.072 184.705 97.167  1.00 270.61 ? 554 TYR C O   1 
ATOM   10197 C CB  . TYR C 3 531 ? 205.944 185.127 95.658  1.00 270.61 ? 554 TYR C CB  1 
ATOM   10198 C CG  . TYR C 3 531 ? 207.150 185.993 95.372  1.00 270.61 ? 554 TYR C CG  1 
ATOM   10199 C CD1 . TYR C 3 531 ? 207.539 186.267 94.067  1.00 270.61 ? 554 TYR C CD1 1 
ATOM   10200 C CD2 . TYR C 3 531 ? 207.903 186.532 96.407  1.00 270.61 ? 554 TYR C CD2 1 
ATOM   10201 C CE1 . TYR C 3 531 ? 208.643 187.055 93.801  1.00 270.61 ? 554 TYR C CE1 1 
ATOM   10202 C CE2 . TYR C 3 531 ? 209.008 187.322 96.151  1.00 270.61 ? 554 TYR C CE2 1 
ATOM   10203 C CZ  . TYR C 3 531 ? 209.373 187.580 94.846  1.00 270.61 ? 554 TYR C CZ  1 
ATOM   10204 O OH  . TYR C 3 531 ? 210.472 188.366 94.586  1.00 270.61 ? 554 TYR C OH  1 
ATOM   10205 N N   . VAL C 3 532 ? 202.956 184.370 94.938  1.00 268.87 ? 555 VAL C N   1 
ATOM   10206 C CA  . VAL C 3 532 ? 201.927 183.337 94.989  1.00 268.87 ? 555 VAL C CA  1 
ATOM   10207 C C   . VAL C 3 532 ? 202.337 182.215 94.047  1.00 268.87 ? 555 VAL C C   1 
ATOM   10208 O O   . VAL C 3 532 ? 202.691 182.469 92.890  1.00 268.87 ? 555 VAL C O   1 
ATOM   10209 C CB  . VAL C 3 532 ? 200.535 183.877 94.607  1.00 268.87 ? 555 VAL C CB  1 
ATOM   10210 C CG1 . VAL C 3 532 ? 199.469 182.827 94.885  1.00 268.87 ? 555 VAL C CG1 1 
ATOM   10211 C CG2 . VAL C 3 532 ? 200.224 185.157 95.364  1.00 268.87 ? 555 VAL C CG2 1 
ATOM   10212 N N   . VAL C 3 533 ? 202.289 180.980 94.539  1.00 270.89 ? 556 VAL C N   1 
ATOM   10213 C CA  . VAL C 3 533 ? 202.632 179.802 93.755  1.00 270.89 ? 556 VAL C CA  1 
ATOM   10214 C C   . VAL C 3 533 ? 201.410 178.897 93.682  1.00 270.89 ? 556 VAL C C   1 
ATOM   10215 O O   . VAL C 3 533 ? 200.604 178.846 94.618  1.00 270.89 ? 556 VAL C O   1 
ATOM   10216 C CB  . VAL C 3 533 ? 203.847 179.055 94.348  1.00 270.89 ? 556 VAL C CB  1 
ATOM   10217 C CG1 . VAL C 3 533 ? 203.485 178.377 95.664  1.00 270.89 ? 556 VAL C CG1 1 
ATOM   10218 C CG2 . VAL C 3 533 ? 204.404 178.049 93.349  1.00 270.89 ? 556 VAL C CG2 1 
ATOM   10219 N N   . ASP C 3 534 ? 201.260 178.202 92.556  1.00 275.67 ? 557 ASP C N   1 
ATOM   10220 C CA  . ASP C 3 534 ? 200.164 177.267 92.359  1.00 275.67 ? 557 ASP C CA  1 
ATOM   10221 C C   . ASP C 3 534 ? 200.652 176.096 91.520  1.00 275.67 ? 557 ASP C C   1 
ATOM   10222 O O   . ASP C 3 534 ? 201.623 176.213 90.769  1.00 275.67 ? 557 ASP C O   1 
ATOM   10223 C CB  . ASP C 3 534 ? 198.955 177.938 91.689  1.00 275.67 ? 557 ASP C CB  1 
ATOM   10224 C CG  . ASP C 3 534 ? 199.354 178.865 90.557  1.00 275.67 ? 557 ASP C CG  1 
ATOM   10225 O OD1 . ASP C 3 534 ? 198.473 179.583 90.037  1.00 275.67 ? 557 ASP C OD1 1 
ATOM   10226 O OD2 . ASP C 3 534 ? 200.546 178.878 90.187  1.00 275.67 ? 557 ASP C OD2 1 
ATOM   10227 N N   . TRP C 3 535 ? 199.966 174.963 91.657  1.00 274.81 ? 558 TRP C N   1 
ATOM   10228 C CA  . TRP C 3 535 ? 200.359 173.747 90.962  1.00 274.81 ? 558 TRP C CA  1 
ATOM   10229 C C   . TRP C 3 535 ? 199.116 172.948 90.606  1.00 274.81 ? 558 TRP C C   1 
ATOM   10230 O O   . TRP C 3 535 ? 198.067 173.070 91.245  1.00 274.81 ? 558 TRP C O   1 
ATOM   10231 C CB  . TRP C 3 535 ? 201.315 172.899 91.810  1.00 274.81 ? 558 TRP C CB  1 
ATOM   10232 C CG  . TRP C 3 535 ? 200.809 172.629 93.194  1.00 274.81 ? 558 TRP C CG  1 
ATOM   10233 C CD1 . TRP C 3 535 ? 200.130 171.524 93.617  1.00 274.81 ? 558 TRP C CD1 1 
ATOM   10234 C CD2 . TRP C 3 535 ? 200.943 173.480 94.339  1.00 274.81 ? 558 TRP C CD2 1 
ATOM   10235 N NE1 . TRP C 3 535 ? 199.832 171.634 94.954  1.00 274.81 ? 558 TRP C NE1 1 
ATOM   10236 C CE2 . TRP C 3 535 ? 200.320 172.826 95.421  1.00 274.81 ? 558 TRP C CE2 1 
ATOM   10237 C CE3 . TRP C 3 535 ? 201.528 174.731 94.555  1.00 274.81 ? 558 TRP C CE3 1 
ATOM   10238 C CZ2 . TRP C 3 535 ? 200.266 173.380 96.698  1.00 274.81 ? 558 TRP C CZ2 1 
ATOM   10239 C CZ3 . TRP C 3 535 ? 201.473 175.280 95.823  1.00 274.81 ? 558 TRP C CZ3 1 
ATOM   10240 C CH2 . TRP C 3 535 ? 200.847 174.605 96.878  1.00 274.81 ? 558 TRP C CH2 1 
ATOM   10241 N N   . CYS C 3 536 ? 199.248 172.122 89.571  1.00 277.93 ? 559 CYS C N   1 
ATOM   10242 C CA  . CYS C 3 536 ? 198.165 171.268 89.107  1.00 277.93 ? 559 CYS C CA  1 
ATOM   10243 C C   . CYS C 3 536 ? 198.695 169.862 88.875  1.00 277.93 ? 559 CYS C C   1 
ATOM   10244 O O   . CYS C 3 536 ? 199.789 169.685 88.333  1.00 277.93 ? 559 CYS C O   1 
ATOM   10245 C CB  . CYS C 3 536 ? 197.537 171.809 87.816  1.00 277.93 ? 559 CYS C CB  1 
ATOM   10246 S SG  . CYS C 3 536 ? 196.221 173.021 88.065  1.00 277.93 ? 559 CYS C SG  1 
ATOM   10247 N N   . ALA C 3 537 ? 197.913 168.867 89.289  1.00 279.81 ? 560 ALA C N   1 
ATOM   10248 C CA  . ALA C 3 537 ? 198.269 167.471 89.059  1.00 279.81 ? 560 ALA C CA  1 
ATOM   10249 C C   . ALA C 3 537 ? 198.067 167.141 87.586  1.00 279.81 ? 560 ALA C C   1 
ATOM   10250 O O   . ALA C 3 537 ? 196.930 167.017 87.119  1.00 279.81 ? 560 ALA C O   1 
ATOM   10251 C CB  . ALA C 3 537 ? 197.431 166.557 89.948  1.00 279.81 ? 560 ALA C CB  1 
ATOM   10252 N N   . HIS C 3 538 ? 199.167 166.998 86.851  1.00 277.24 ? 561 HIS C N   1 
ATOM   10253 C CA  . HIS C 3 538 ? 199.109 166.771 85.409  1.00 277.24 ? 561 HIS C CA  1 
ATOM   10254 C C   . HIS C 3 538 ? 198.800 165.301 85.152  1.00 277.24 ? 561 HIS C C   1 
ATOM   10255 O O   . HIS C 3 538 ? 199.687 164.446 85.204  1.00 277.24 ? 561 HIS C O   1 
ATOM   10256 C CB  . HIS C 3 538 ? 200.418 167.185 84.747  1.00 277.24 ? 561 HIS C CB  1 
ATOM   10257 C CG  . HIS C 3 538 ? 200.248 167.735 83.366  1.00 277.24 ? 561 HIS C CG  1 
ATOM   10258 N ND1 . HIS C 3 538 ? 199.740 168.993 83.123  1.00 277.24 ? 561 HIS C ND1 1 
ATOM   10259 C CD2 . HIS C 3 538 ? 200.511 167.195 82.153  1.00 277.24 ? 561 HIS C CD2 1 
ATOM   10260 C CE1 . HIS C 3 538 ? 199.702 169.206 81.819  1.00 277.24 ? 561 HIS C CE1 1 
ATOM   10261 N NE2 . HIS C 3 538 ? 200.164 168.130 81.208  1.00 277.24 ? 561 HIS C NE2 1 
ATOM   10262 N N   . SER C 3 539 ? 197.531 165.006 84.872  1.00 284.75 ? 562 SER C N   1 
ATOM   10263 C CA  . SER C 3 539 ? 197.111 163.648 84.552  1.00 284.75 ? 562 SER C CA  1 
ATOM   10264 C C   . SER C 3 539 ? 196.260 163.643 83.288  1.00 284.75 ? 562 SER C C   1 
ATOM   10265 O O   . SER C 3 539 ? 196.173 164.657 82.588  1.00 284.75 ? 562 SER C O   1 
ATOM   10266 C CB  . SER C 3 539 ? 196.347 163.026 85.722  1.00 284.75 ? 562 SER C CB  1 
ATOM   10267 O OG  . SER C 3 539 ? 197.176 162.904 86.865  1.00 284.75 ? 562 SER C OG  1 
ATOM   10268 N N   . GLN C 3 540 ? 195.628 162.508 82.988  1.00 289.67 ? 563 GLN C N   1 
ATOM   10269 C CA  . GLN C 3 540 ? 194.920 162.338 81.723  1.00 289.67 ? 563 GLN C CA  1 
ATOM   10270 C C   . GLN C 3 540 ? 193.478 162.841 81.787  1.00 289.67 ? 563 GLN C C   1 
ATOM   10271 O O   . GLN C 3 540 ? 193.089 163.725 81.018  1.00 289.67 ? 563 GLN C O   1 
ATOM   10272 C CB  . GLN C 3 540 ? 194.952 160.864 81.302  1.00 289.67 ? 563 GLN C CB  1 
ATOM   10273 C CG  . GLN C 3 540 ? 196.349 160.309 81.072  1.00 289.67 ? 563 GLN C CG  1 
ATOM   10274 C CD  . GLN C 3 540 ? 196.978 159.761 82.339  1.00 289.67 ? 563 GLN C CD  1 
ATOM   10275 O OE1 . GLN C 3 540 ? 196.310 159.611 83.362  1.00 289.67 ? 563 GLN C OE1 1 
ATOM   10276 N NE2 . GLN C 3 540 ? 198.270 159.460 82.276  1.00 289.67 ? 563 GLN C NE2 1 
ATOM   10277 N N   . ASP C 3 541 ? 192.677 162.289 82.699  1.00 292.72 ? 564 ASP C N   1 
ATOM   10278 C CA  . ASP C 3 541 ? 191.239 162.534 82.679  1.00 292.72 ? 564 ASP C CA  1 
ATOM   10279 C C   . ASP C 3 541 ? 190.730 163.167 83.969  1.00 292.72 ? 564 ASP C C   1 
ATOM   10280 O O   . ASP C 3 541 ? 189.719 162.722 84.522  1.00 292.72 ? 564 ASP C O   1 
ATOM   10281 C CB  . ASP C 3 541 ? 190.488 161.227 82.414  1.00 292.72 ? 564 ASP C CB  1 
ATOM   10282 C CG  . ASP C 3 541 ? 191.094 160.426 81.279  1.00 292.72 ? 564 ASP C CG  1 
ATOM   10283 O OD1 . ASP C 3 541 ? 190.942 160.840 80.110  1.00 292.72 ? 564 ASP C OD1 1 
ATOM   10284 O OD2 . ASP C 3 541 ? 191.723 159.383 81.555  1.00 292.72 ? 564 ASP C OD2 1 
ATOM   10285 N N   . GLN C 3 542 ? 191.413 164.199 84.460  1.00 285.41 ? 565 GLN C N   1 
ATOM   10286 C CA  . GLN C 3 542 ? 190.978 164.890 85.665  1.00 285.41 ? 565 GLN C CA  1 
ATOM   10287 C C   . GLN C 3 542 ? 191.160 166.391 85.491  1.00 285.41 ? 565 GLN C C   1 
ATOM   10288 O O   . GLN C 3 542 ? 191.947 166.853 84.661  1.00 285.41 ? 565 GLN C O   1 
ATOM   10289 C CB  . GLN C 3 542 ? 191.738 164.396 86.908  1.00 285.41 ? 565 GLN C CB  1 
ATOM   10290 C CG  . GLN C 3 542 ? 193.258 164.395 86.778  1.00 285.41 ? 565 GLN C CG  1 
ATOM   10291 C CD  . GLN C 3 542 ? 193.871 165.779 86.896  1.00 285.41 ? 565 GLN C CD  1 
ATOM   10292 O OE1 . GLN C 3 542 ? 193.378 166.628 87.638  1.00 285.41 ? 565 GLN C OE1 1 
ATOM   10293 N NE2 . GLN C 3 542 ? 194.948 166.015 86.156  1.00 285.41 ? 565 GLN C NE2 1 
ATOM   10294 N N   . ARG C 3 543 ? 190.415 167.149 86.291  1.00 280.35 ? 566 ARG C N   1 
ATOM   10295 C CA  . ARG C 3 543 ? 190.556 168.597 86.368  1.00 280.35 ? 566 ARG C CA  1 
ATOM   10296 C C   . ARG C 3 543 ? 191.307 168.936 87.650  1.00 280.35 ? 566 ARG C C   1 
ATOM   10297 O O   . ARG C 3 543 ? 190.868 168.571 88.746  1.00 280.35 ? 566 ARG C O   1 
ATOM   10298 C CB  . ARG C 3 543 ? 189.192 169.286 86.337  1.00 280.35 ? 566 ARG C CB  1 
ATOM   10299 C CG  . ARG C 3 543 ? 188.292 168.830 85.199  1.00 280.35 ? 566 ARG C CG  1 
ATOM   10300 C CD  . ARG C 3 543 ? 186.905 169.442 85.311  1.00 280.35 ? 566 ARG C CD  1 
ATOM   10301 N NE  . ARG C 3 543 ? 185.999 168.933 84.286  1.00 280.35 ? 566 ARG C NE  1 
ATOM   10302 C CZ  . ARG C 3 543 ? 184.714 169.261 84.194  1.00 280.35 ? 566 ARG C CZ  1 
ATOM   10303 N NH1 . ARG C 3 543 ? 184.178 170.102 85.069  1.00 280.35 ? 566 ARG C NH1 1 
ATOM   10304 N NH2 . ARG C 3 543 ? 183.964 168.750 83.227  1.00 280.35 ? 566 ARG C NH2 1 
ATOM   10305 N N   . CYS C 3 544 ? 192.435 169.627 87.510  1.00 273.93 ? 567 CYS C N   1 
ATOM   10306 C CA  . CYS C 3 544 ? 193.301 169.883 88.652  1.00 273.93 ? 567 CYS C CA  1 
ATOM   10307 C C   . CYS C 3 544 ? 192.646 170.850 89.630  1.00 273.93 ? 567 CYS C C   1 
ATOM   10308 O O   . CYS C 3 544 ? 191.924 171.770 89.234  1.00 273.93 ? 567 CYS C O   1 
ATOM   10309 C CB  . CYS C 3 544 ? 194.644 170.441 88.185  1.00 273.93 ? 567 CYS C CB  1 
ATOM   10310 S SG  . CYS C 3 544 ? 194.553 172.070 87.405  1.00 273.93 ? 567 CYS C SG  1 
ATOM   10311 N N   . ASP C 3 545 ? 192.901 170.632 90.917  1.00 264.04 ? 568 ASP C N   1 
ATOM   10312 C CA  . ASP C 3 545 ? 192.426 171.520 91.973  1.00 264.04 ? 568 ASP C CA  1 
ATOM   10313 C C   . ASP C 3 545 ? 193.496 172.575 92.225  1.00 264.04 ? 568 ASP C C   1 
ATOM   10314 O O   . ASP C 3 545 ? 194.554 172.275 92.788  1.00 264.04 ? 568 ASP C O   1 
ATOM   10315 C CB  . ASP C 3 545 ? 192.113 170.733 93.243  1.00 264.04 ? 568 ASP C CB  1 
ATOM   10316 C CG  . ASP C 3 545 ? 191.135 171.454 94.148  1.00 264.04 ? 568 ASP C CG  1 
ATOM   10317 O OD1 . ASP C 3 545 ? 189.928 171.136 94.095  1.00 264.04 ? 568 ASP C OD1 1 
ATOM   10318 O OD2 . ASP C 3 545 ? 191.573 172.339 94.913  1.00 264.04 ? 568 ASP C OD2 1 
ATOM   10319 N N   . LEU C 3 546 ? 193.224 173.807 91.803  1.00 266.58 ? 569 LEU C N   1 
ATOM   10320 C CA  . LEU C 3 546 ? 194.200 174.887 91.907  1.00 266.58 ? 569 LEU C CA  1 
ATOM   10321 C C   . LEU C 3 546 ? 194.417 175.242 93.372  1.00 266.58 ? 569 LEU C C   1 
ATOM   10322 O O   . LEU C 3 546 ? 193.565 175.880 94.000  1.00 266.58 ? 569 LEU C O   1 
ATOM   10323 C CB  . LEU C 3 546 ? 193.724 176.100 91.113  1.00 266.58 ? 569 LEU C CB  1 
ATOM   10324 C CG  . LEU C 3 546 ? 194.777 177.165 90.799  1.00 266.58 ? 569 LEU C CG  1 
ATOM   10325 C CD1 . LEU C 3 546 ? 195.894 176.579 89.951  1.00 266.58 ? 569 LEU C CD1 1 
ATOM   10326 C CD2 . LEU C 3 546 ? 194.139 178.355 90.101  1.00 266.58 ? 569 LEU C CD2 1 
ATOM   10327 N N   . GLN C 3 547 ? 195.557 174.830 93.920  1.00 269.15 ? 570 GLN C N   1 
ATOM   10328 C CA  . GLN C 3 547 ? 195.933 175.125 95.295  1.00 269.15 ? 570 GLN C CA  1 
ATOM   10329 C C   . GLN C 3 547 ? 197.020 176.190 95.298  1.00 269.15 ? 570 GLN C C   1 
ATOM   10330 O O   . GLN C 3 547 ? 197.976 176.108 94.519  1.00 269.15 ? 570 GLN C O   1 
ATOM   10331 C CB  . GLN C 3 547 ? 196.419 173.865 96.015  1.00 269.15 ? 570 GLN C CB  1 
ATOM   10332 C CG  . GLN C 3 547 ? 196.752 174.078 97.483  1.00 269.15 ? 570 GLN C CG  1 
ATOM   10333 C CD  . GLN C 3 547 ? 197.224 172.808 98.164  1.00 269.15 ? 570 GLN C CD  1 
ATOM   10334 O OE1 . GLN C 3 547 ? 197.414 171.778 97.518  1.00 269.15 ? 570 GLN C OE1 1 
ATOM   10335 N NE2 . GLN C 3 547 ? 197.416 172.877 99.476  1.00 269.15 ? 570 GLN C NE2 1 
ATOM   10336 N N   . TRP C 3 548 ? 196.874 177.182 96.173  1.00 261.12 ? 571 TRP C N   1 
ATOM   10337 C CA  . TRP C 3 548 ? 197.806 178.298 96.236  1.00 261.12 ? 571 TRP C CA  1 
ATOM   10338 C C   . TRP C 3 548 ? 198.014 178.705 97.687  1.00 261.12 ? 571 TRP C C   1 
ATOM   10339 O O   . TRP C 3 548 ? 197.239 178.344 98.575  1.00 261.12 ? 571 TRP C O   1 
ATOM   10340 C CB  . TRP C 3 548 ? 197.305 179.497 95.419  1.00 261.12 ? 571 TRP C CB  1 
ATOM   10341 C CG  . TRP C 3 548 ? 196.137 180.196 96.044  1.00 261.12 ? 571 TRP C CG  1 
ATOM   10342 C CD1 . TRP C 3 548 ? 196.162 181.366 96.746  1.00 261.12 ? 571 TRP C CD1 1 
ATOM   10343 C CD2 . TRP C 3 548 ? 194.770 179.767 96.029  1.00 261.12 ? 571 TRP C CD2 1 
ATOM   10344 N NE1 . TRP C 3 548 ? 194.895 181.693 97.166  1.00 261.12 ? 571 TRP C NE1 1 
ATOM   10345 C CE2 . TRP C 3 548 ? 194.023 180.726 96.739  1.00 261.12 ? 571 TRP C CE2 1 
ATOM   10346 C CE3 . TRP C 3 548 ? 194.106 178.665 95.481  1.00 261.12 ? 571 TRP C CE3 1 
ATOM   10347 C CZ2 . TRP C 3 548 ? 192.645 180.618 96.917  1.00 261.12 ? 571 TRP C CZ2 1 
ATOM   10348 C CZ3 . TRP C 3 548 ? 192.739 178.558 95.659  1.00 261.12 ? 571 TRP C CZ3 1 
ATOM   10349 C CH2 . TRP C 3 548 ? 192.024 179.529 96.371  1.00 261.12 ? 571 TRP C CH2 1 
ATOM   10350 N N   . LYS C 3 549 ? 199.082 179.467 97.915  1.00 266.44 ? 572 LYS C N   1 
ATOM   10351 C CA  . LYS C 3 549 ? 199.392 179.982 99.239  1.00 266.44 ? 572 LYS C CA  1 
ATOM   10352 C C   . LYS C 3 549 ? 200.024 181.358 99.095  1.00 266.44 ? 572 LYS C C   1 
ATOM   10353 O O   . LYS C 3 549 ? 200.736 181.632 98.125  1.00 266.44 ? 572 LYS C O   1 
ATOM   10354 C CB  . LYS C 3 549 ? 200.326 179.041 100.010 1.00 266.44 ? 572 LYS C CB  1 
ATOM   10355 C CG  . LYS C 3 549 ? 201.573 178.634 99.245  1.00 266.44 ? 572 LYS C CG  1 
ATOM   10356 C CD  . LYS C 3 549 ? 202.387 177.617 100.028 1.00 266.44 ? 572 LYS C CD  1 
ATOM   10357 C CE  . LYS C 3 549 ? 201.562 176.381 100.349 1.00 266.44 ? 572 LYS C CE  1 
ATOM   10358 N NZ  . LYS C 3 549 ? 202.307 175.421 101.209 1.00 266.44 ? 572 LYS C NZ  1 
ATOM   10359 N N   . ASN C 3 550 ? 199.755 182.221 100.071 1.00 266.80 ? 573 ASN C N   1 
ATOM   10360 C CA  . ASN C 3 550 ? 200.257 183.588 100.055 1.00 266.80 ? 573 ASN C CA  1 
ATOM   10361 C C   . ASN C 3 550 ? 201.603 183.654 100.765 1.00 266.80 ? 573 ASN C C   1 
ATOM   10362 O O   . ASN C 3 550 ? 201.741 183.178 101.896 1.00 266.80 ? 573 ASN C O   1 
ATOM   10363 C CB  . ASN C 3 550 ? 199.260 184.537 100.720 1.00 266.80 ? 573 ASN C CB  1 
ATOM   10364 C CG  . ASN C 3 550 ? 199.682 185.991 100.623 1.00 266.80 ? 573 ASN C CG  1 
ATOM   10365 O OD1 . ASN C 3 550 ? 199.329 186.809 101.472 1.00 266.80 ? 573 ASN C OD1 1 
ATOM   10366 N ND2 . ASN C 3 550 ? 200.435 186.321 99.580  1.00 266.80 ? 573 ASN C ND2 1 
ATOM   10367 N N   . LEU C 3 551 ? 202.590 184.244 100.097 1.00 267.59 ? 574 LEU C N   1 
ATOM   10368 C CA  . LEU C 3 551 ? 203.919 184.432 100.653 1.00 267.59 ? 574 LEU C CA  1 
ATOM   10369 C C   . LEU C 3 551 ? 204.258 185.917 100.688 1.00 267.59 ? 574 LEU C C   1 
ATOM   10370 O O   . LEU C 3 551 ? 203.627 186.737 100.015 1.00 267.59 ? 574 LEU C O   1 
ATOM   10371 C CB  . LEU C 3 551 ? 204.979 183.666 99.847  1.00 267.59 ? 574 LEU C CB  1 
ATOM   10372 C CG  . LEU C 3 551 ? 204.744 182.167 99.633  1.00 267.59 ? 574 LEU C CG  1 
ATOM   10373 C CD1 . LEU C 3 551 ? 204.065 181.892 98.300  1.00 267.59 ? 574 LEU C CD1 1 
ATOM   10374 C CD2 . LEU C 3 551 ? 206.054 181.404 99.732  1.00 267.59 ? 574 LEU C CD2 1 
ATOM   10375 N N   . GLY C 3 552 ? 205.267 186.255 101.487 1.00 268.01 ? 575 GLY C N   1 
ATOM   10376 C CA  . GLY C 3 552 ? 205.669 187.629 101.665 1.00 268.01 ? 575 GLY C CA  1 
ATOM   10377 C C   . GLY C 3 552 ? 206.694 188.076 100.644 1.00 268.01 ? 575 GLY C C   1 
ATOM   10378 O O   . GLY C 3 552 ? 207.175 187.290 99.822  1.00 268.01 ? 575 GLY C O   1 
ATOM   10379 N N   . PRO C 3 553 ? 207.046 189.366 100.674 1.00 267.33 ? 576 PRO C N   1 
ATOM   10380 C CA  . PRO C 3 553 ? 208.045 189.882 99.730  1.00 267.33 ? 576 PRO C CA  1 
ATOM   10381 C C   . PRO C 3 553 ? 209.482 189.702 100.189 1.00 267.33 ? 576 PRO C C   1 
ATOM   10382 O O   . PRO C 3 553 ? 210.400 190.036 99.427  1.00 267.33 ? 576 PRO C O   1 
ATOM   10383 C CB  . PRO C 3 553 ? 207.685 191.368 99.634  1.00 267.33 ? 576 PRO C CB  1 
ATOM   10384 C CG  . PRO C 3 553 ? 207.136 191.691 100.989 1.00 267.33 ? 576 PRO C CG  1 
ATOM   10385 C CD  . PRO C 3 553 ? 206.489 190.430 101.527 1.00 267.33 ? 576 PRO C CD  1 
ATOM   10386 N N   . ASN C 3 554 ? 209.708 189.193 101.399 1.00 270.86 ? 577 ASN C N   1 
ATOM   10387 C CA  . ASN C 3 554 ? 211.050 189.028 101.942 1.00 270.86 ? 577 ASN C CA  1 
ATOM   10388 C C   . ASN C 3 554 ? 211.515 187.578 101.934 1.00 270.86 ? 577 ASN C C   1 
ATOM   10389 O O   . ASN C 3 554 ? 212.529 187.260 102.564 1.00 270.86 ? 577 ASN C O   1 
ATOM   10390 C CB  . ASN C 3 554 ? 211.113 189.589 103.365 1.00 270.86 ? 577 ASN C CB  1 
ATOM   10391 C CG  . ASN C 3 554 ? 210.042 189.008 104.267 1.00 270.86 ? 577 ASN C CG  1 
ATOM   10392 O OD1 . ASN C 3 554 ? 209.092 188.381 103.799 1.00 270.86 ? 577 ASN C OD1 1 
ATOM   10393 N ND2 . ASN C 3 554 ? 210.190 189.215 105.571 1.00 270.86 ? 577 ASN C ND2 1 
ATOM   10394 N N   . THR C 3 555 ? 210.806 186.694 101.241 1.00 272.32 ? 578 THR C N   1 
ATOM   10395 C CA  . THR C 3 555 ? 211.168 185.288 101.161 1.00 272.32 ? 578 THR C CA  1 
ATOM   10396 C C   . THR C 3 555 ? 211.577 184.927 99.739  1.00 272.32 ? 578 THR C C   1 
ATOM   10397 O O   . THR C 3 555 ? 211.187 185.581 98.768  1.00 272.32 ? 578 THR C O   1 
ATOM   10398 C CB  . THR C 3 555 ? 210.010 184.390 101.615 1.00 272.32 ? 578 THR C CB  1 
ATOM   10399 O OG1 . THR C 3 555 ? 210.393 183.015 101.494 1.00 272.32 ? 578 THR C OG1 1 
ATOM   10400 C CG2 . THR C 3 555 ? 208.774 184.641 100.767 1.00 272.32 ? 578 THR C CG2 1 
ATOM   10401 N N   . THR C 3 556 ? 212.381 183.870 99.630  1.00 275.22 ? 579 THR C N   1 
ATOM   10402 C CA  . THR C 3 556 ? 212.857 183.386 98.340  1.00 275.22 ? 579 THR C CA  1 
ATOM   10403 C C   . THR C 3 556 ? 212.631 181.899 98.111  1.00 275.22 ? 579 THR C C   1 
ATOM   10404 O O   . THR C 3 556 ? 212.574 181.481 96.949  1.00 275.22 ? 579 THR C O   1 
ATOM   10405 C CB  . THR C 3 556 ? 214.355 183.683 98.171  1.00 275.22 ? 579 THR C CB  1 
ATOM   10406 O OG1 . THR C 3 556 ? 215.063 183.270 99.346  1.00 275.22 ? 579 THR C OG1 1 
ATOM   10407 C CG2 . THR C 3 556 ? 214.582 185.171 97.943  1.00 275.22 ? 579 THR C CG2 1 
ATOM   10408 N N   . SER C 3 557 ? 212.502 181.091 99.162  1.00 275.66 ? 580 SER C N   1 
ATOM   10409 C CA  . SER C 3 557 ? 212.281 179.661 99.013  1.00 275.66 ? 580 SER C CA  1 
ATOM   10410 C C   . SER C 3 557 ? 211.444 179.166 100.183 1.00 275.66 ? 580 SER C C   1 
ATOM   10411 O O   . SER C 3 557 ? 211.713 179.513 101.336 1.00 275.66 ? 580 SER C O   1 
ATOM   10412 C CB  . SER C 3 557 ? 213.605 178.893 98.945  1.00 275.66 ? 580 SER C CB  1 
ATOM   10413 O OG  . SER C 3 557 ? 214.163 178.954 97.644  1.00 275.66 ? 580 SER C OG  1 
ATOM   10414 N N   . THR C 3 558 ? 210.433 178.356 99.878  1.00 277.51 ? 581 THR C N   1 
ATOM   10415 C CA  . THR C 3 558 ? 209.548 177.813 100.897 1.00 277.51 ? 581 THR C CA  1 
ATOM   10416 C C   . THR C 3 558 ? 209.145 176.400 100.504 1.00 277.51 ? 581 THR C C   1 
ATOM   10417 O O   . THR C 3 558 ? 208.855 176.132 99.334  1.00 277.51 ? 581 THR C O   1 
ATOM   10418 C CB  . THR C 3 558 ? 208.299 178.684 101.083 1.00 277.51 ? 581 THR C CB  1 
ATOM   10419 O OG1 . THR C 3 558 ? 208.676 180.066 101.110 1.00 277.51 ? 581 THR C OG1 1 
ATOM   10420 C CG2 . THR C 3 558 ? 207.591 178.333 102.383 1.00 277.51 ? 581 THR C CG2 1 
ATOM   10421 N N   . THR C 3 559 ? 209.130 175.503 101.486 1.00 279.02 ? 582 THR C N   1 
ATOM   10422 C CA  . THR C 3 559 ? 208.763 174.111 101.266 1.00 279.02 ? 582 THR C CA  1 
ATOM   10423 C C   . THR C 3 559 ? 207.274 173.934 101.537 1.00 279.02 ? 582 THR C C   1 
ATOM   10424 O O   . THR C 3 559 ? 206.793 174.263 102.627 1.00 279.02 ? 582 THR C O   1 
ATOM   10425 C CB  . THR C 3 559 ? 209.585 173.185 102.161 1.00 279.02 ? 582 THR C CB  1 
ATOM   10426 O OG1 . THR C 3 559 ? 209.030 173.178 103.482 1.00 279.02 ? 582 THR C OG1 1 
ATOM   10427 C CG2 . THR C 3 559 ? 211.031 173.655 102.228 1.00 279.02 ? 582 THR C CG2 1 
ATOM   10428 N N   . ILE C 3 560 ? 206.550 173.418 100.551 1.00 282.55 ? 583 ILE C N   1 
ATOM   10429 C CA  . ILE C 3 560 ? 205.113 173.206 100.668 1.00 282.55 ? 583 ILE C CA  1 
ATOM   10430 C C   . ILE C 3 560 ? 204.854 171.793 101.173 1.00 282.55 ? 583 ILE C C   1 
ATOM   10431 O O   . ILE C 3 560 ? 205.591 170.850 100.866 1.00 282.55 ? 583 ILE C O   1 
ATOM   10432 C CB  . ILE C 3 560 ? 204.401 173.469 99.323  1.00 282.55 ? 583 ILE C CB  1 
ATOM   10433 C CG1 . ILE C 3 560 ? 204.807 172.426 98.279  1.00 282.55 ? 583 ILE C CG1 1 
ATOM   10434 C CG2 . ILE C 3 560 ? 204.709 174.873 98.824  1.00 282.55 ? 583 ILE C CG2 1 
ATOM   10435 C CD1 . ILE C 3 560 ? 203.896 172.383 97.072  1.00 282.55 ? 583 ILE C CD1 1 
ATOM   10436 N N   . THR C 3 561 ? 203.801 171.650 101.976 1.00 291.27 ? 584 THR C N   1 
ATOM   10437 C CA  . THR C 3 561 ? 203.407 170.367 102.541 1.00 291.27 ? 584 THR C CA  1 
ATOM   10438 C C   . THR C 3 561 ? 201.958 170.080 102.183 1.00 291.27 ? 584 THR C C   1 
ATOM   10439 O O   . THR C 3 561 ? 201.095 170.957 102.299 1.00 291.27 ? 584 THR C O   1 
ATOM   10440 C CB  . THR C 3 561 ? 203.575 170.342 104.069 1.00 291.27 ? 584 THR C CB  1 
ATOM   10441 O OG1 . THR C 3 561 ? 202.474 171.021 104.685 1.00 291.27 ? 584 THR C OG1 1 
ATOM   10442 C CG2 . THR C 3 561 ? 204.877 171.015 104.483 1.00 291.27 ? 584 THR C CG2 1 
ATOM   10443 N N   . SER C 3 562 ? 201.695 168.849 101.750 1.00 291.79 ? 585 SER C N   1 
ATOM   10444 C CA  . SER C 3 562 ? 200.348 168.436 101.383 1.00 291.79 ? 585 SER C CA  1 
ATOM   10445 C C   . SER C 3 562 ? 200.293 166.916 101.355 1.00 291.79 ? 585 SER C C   1 
ATOM   10446 O O   . SER C 3 562 ? 201.244 166.263 100.918 1.00 291.79 ? 585 SER C O   1 
ATOM   10447 C CB  . SER C 3 562 ? 199.936 169.011 100.023 1.00 291.79 ? 585 SER C CB  1 
ATOM   10448 O OG  . SER C 3 562 ? 200.403 168.196 98.963  1.00 291.79 ? 585 SER C OG  1 
ATOM   10449 N N   . ASP C 3 563 ? 199.175 166.361 101.824 1.00 292.34 ? 586 ASP C N   1 
ATOM   10450 C CA  . ASP C 3 563 ? 199.006 164.915 101.881 1.00 292.34 ? 586 ASP C CA  1 
ATOM   10451 C C   . ASP C 3 563 ? 198.481 164.321 100.580 1.00 292.34 ? 586 ASP C C   1 
ATOM   10452 O O   . ASP C 3 563 ? 198.538 163.098 100.413 1.00 292.34 ? 586 ASP C O   1 
ATOM   10453 C CB  . ASP C 3 563 ? 198.066 164.541 103.029 1.00 292.34 ? 586 ASP C CB  1 
ATOM   10454 C CG  . ASP C 3 563 ? 198.800 164.338 104.340 1.00 292.34 ? 586 ASP C CG  1 
ATOM   10455 O OD1 . ASP C 3 563 ? 199.649 163.425 104.412 1.00 292.34 ? 586 ASP C OD1 1 
ATOM   10456 O OD2 . ASP C 3 563 ? 198.528 165.092 105.298 1.00 292.34 ? 586 ASP C OD2 1 
ATOM   10457 N N   . ASP C 3 564 ? 197.976 165.144 99.663  1.00 288.45 ? 587 ASP C N   1 
ATOM   10458 C CA  . ASP C 3 564 ? 197.456 164.649 98.394  1.00 288.45 ? 587 ASP C CA  1 
ATOM   10459 C C   . ASP C 3 564 ? 198.551 164.346 97.379  1.00 288.45 ? 587 ASP C C   1 
ATOM   10460 O O   . ASP C 3 564 ? 198.244 163.833 96.298  1.00 288.45 ? 587 ASP C O   1 
ATOM   10461 C CB  . ASP C 3 564 ? 196.468 165.659 97.800  1.00 288.45 ? 587 ASP C CB  1 
ATOM   10462 C CG  . ASP C 3 564 ? 197.150 166.916 97.296  1.00 288.45 ? 587 ASP C CG  1 
ATOM   10463 O OD1 . ASP C 3 564 ? 198.161 167.330 97.900  1.00 288.45 ? 587 ASP C OD1 1 
ATOM   10464 O OD2 . ASP C 3 564 ? 196.674 167.491 96.294  1.00 288.45 ? 587 ASP C OD2 1 
ATOM   10465 N N   . PHE C 3 565 ? 199.807 164.649 97.695  1.00 281.16 ? 588 PHE C N   1 
ATOM   10466 C CA  . PHE C 3 565 ? 200.905 164.386 96.772  1.00 281.16 ? 588 PHE C CA  1 
ATOM   10467 C C   . PHE C 3 565 ? 201.199 162.892 96.730  1.00 281.16 ? 588 PHE C C   1 
ATOM   10468 O O   . PHE C 3 565 ? 201.542 162.290 97.752  1.00 281.16 ? 588 PHE C O   1 
ATOM   10469 C CB  . PHE C 3 565 ? 202.148 165.164 97.195  1.00 281.16 ? 588 PHE C CB  1 
ATOM   10470 C CG  . PHE C 3 565 ? 202.097 166.625 96.851  1.00 281.16 ? 588 PHE C CG  1 
ATOM   10471 C CD1 . PHE C 3 565 ? 201.084 167.128 96.052  1.00 281.16 ? 588 PHE C CD1 1 
ATOM   10472 C CD2 . PHE C 3 565 ? 203.064 167.494 97.326  1.00 281.16 ? 588 PHE C CD2 1 
ATOM   10473 C CE1 . PHE C 3 565 ? 201.035 168.472 95.735  1.00 281.16 ? 588 PHE C CE1 1 
ATOM   10474 C CE2 . PHE C 3 565 ? 203.021 168.839 97.012  1.00 281.16 ? 588 PHE C CE2 1 
ATOM   10475 C CZ  . PHE C 3 565 ? 202.005 169.328 96.215  1.00 281.16 ? 588 PHE C CZ  1 
ATOM   10476 N N   . LYS C 3 566 ? 201.063 162.292 95.548  1.00 275.87 ? 589 LYS C N   1 
ATOM   10477 C CA  . LYS C 3 566 ? 201.333 160.876 95.394  1.00 275.87 ? 589 LYS C CA  1 
ATOM   10478 C C   . LYS C 3 566 ? 202.412 160.649 94.343  1.00 275.87 ? 589 LYS C C   1 
ATOM   10479 O O   . LYS C 3 566 ? 202.495 161.404 93.367  1.00 275.87 ? 589 LYS C O   1 
ATOM   10480 C CB  . LYS C 3 566 ? 200.050 160.107 95.015  1.00 275.87 ? 589 LYS C CB  1 
ATOM   10481 C CG  . LYS C 3 566 ? 199.432 160.456 93.659  1.00 275.87 ? 589 LYS C CG  1 
ATOM   10482 C CD  . LYS C 3 566 ? 199.968 159.579 92.529  1.00 275.87 ? 589 LYS C CD  1 
ATOM   10483 C CE  . LYS C 3 566 ? 199.173 159.774 91.249  1.00 275.87 ? 589 LYS C CE  1 
ATOM   10484 N NZ  . LYS C 3 566 ? 199.797 159.072 90.095  1.00 275.87 ? 589 LYS C NZ  1 
ATOM   10485 N N   . PRO C 3 567 ? 203.258 159.636 94.518  1.00 273.02 ? 590 PRO C N   1 
ATOM   10486 C CA  . PRO C 3 567 ? 204.295 159.363 93.515  1.00 273.02 ? 590 PRO C CA  1 
ATOM   10487 C C   . PRO C 3 567 ? 203.693 158.846 92.217  1.00 273.02 ? 590 PRO C C   1 
ATOM   10488 O O   . PRO C 3 567 ? 202.832 157.963 92.216  1.00 273.02 ? 590 PRO C O   1 
ATOM   10489 C CB  . PRO C 3 567 ? 205.172 158.298 94.188  1.00 273.02 ? 590 PRO C CB  1 
ATOM   10490 C CG  . PRO C 3 567 ? 204.823 158.363 95.651  1.00 273.02 ? 590 PRO C CG  1 
ATOM   10491 C CD  . PRO C 3 567 ? 203.386 158.767 95.698  1.00 273.02 ? 590 PRO C CD  1 
ATOM   10492 N N   . GLY C 3 568 ? 204.161 159.405 91.105  1.00 273.40 ? 591 GLY C N   1 
ATOM   10493 C CA  . GLY C 3 568 ? 203.692 159.027 89.783  1.00 273.40 ? 591 GLY C CA  1 
ATOM   10494 C C   . GLY C 3 568 ? 203.015 160.134 89.003  1.00 273.40 ? 591 GLY C C   1 
ATOM   10495 O O   . GLY C 3 568 ? 202.713 159.935 87.816  1.00 273.40 ? 591 GLY C O   1 
ATOM   10496 N N   . VAL C 3 569 ? 202.756 161.291 89.606  1.00 277.52 ? 592 VAL C N   1 
ATOM   10497 C CA  . VAL C 3 569 ? 202.106 162.401 88.923  1.00 277.52 ? 592 VAL C CA  1 
ATOM   10498 C C   . VAL C 3 569 ? 203.008 163.625 89.010  1.00 277.52 ? 592 VAL C C   1 
ATOM   10499 O O   . VAL C 3 569 ? 203.660 163.872 90.030  1.00 277.52 ? 592 VAL C O   1 
ATOM   10500 C CB  . VAL C 3 569 ? 200.706 162.695 89.513  1.00 277.52 ? 592 VAL C CB  1 
ATOM   10501 C CG1 . VAL C 3 569 ? 200.801 162.999 91.002  1.00 277.52 ? 592 VAL C CG1 1 
ATOM   10502 C CG2 . VAL C 3 569 ? 200.022 163.831 88.762  1.00 277.52 ? 592 VAL C CG2 1 
ATOM   10503 N N   . ARG C 3 570 ? 203.050 164.388 87.922  1.00 277.87 ? 593 ARG C N   1 
ATOM   10504 C CA  . ARG C 3 570 ? 203.860 165.594 87.840  1.00 277.87 ? 593 ARG C CA  1 
ATOM   10505 C C   . ARG C 3 570 ? 203.026 166.810 88.223  1.00 277.87 ? 593 ARG C C   1 
ATOM   10506 O O   . ARG C 3 570 ? 201.856 166.919 87.845  1.00 277.87 ? 593 ARG C O   1 
ATOM   10507 C CB  . ARG C 3 570 ? 204.427 165.774 86.430  1.00 277.87 ? 593 ARG C CB  1 
ATOM   10508 C CG  . ARG C 3 570 ? 205.463 166.881 86.308  1.00 277.87 ? 593 ARG C CG  1 
ATOM   10509 C CD  . ARG C 3 570 ? 205.800 167.157 84.851  1.00 277.87 ? 593 ARG C CD  1 
ATOM   10510 N NE  . ARG C 3 570 ? 204.657 167.695 84.119  1.00 277.87 ? 593 ARG C NE  1 
ATOM   10511 C CZ  . ARG C 3 570 ? 204.674 168.008 82.828  1.00 277.87 ? 593 ARG C CZ  1 
ATOM   10512 N NH1 . ARG C 3 570 ? 205.779 167.836 82.115  1.00 277.87 ? 593 ARG C NH1 1 
ATOM   10513 N NH2 . ARG C 3 570 ? 203.585 168.492 82.247  1.00 277.87 ? 593 ARG C NH2 1 
ATOM   10514 N N   . TYR C 3 571 ? 203.638 167.723 88.974  1.00 279.14 ? 594 TYR C N   1 
ATOM   10515 C CA  . TYR C 3 571 ? 202.996 168.962 89.400  1.00 279.14 ? 594 TYR C CA  1 
ATOM   10516 C C   . TYR C 3 571 ? 203.747 170.125 88.767  1.00 279.14 ? 594 TYR C C   1 
ATOM   10517 O O   . TYR C 3 571 ? 204.921 170.354 89.076  1.00 279.14 ? 594 TYR C O   1 
ATOM   10518 C CB  . TYR C 3 571 ? 202.981 169.080 90.924  1.00 279.14 ? 594 TYR C CB  1 
ATOM   10519 C CG  . TYR C 3 571 ? 202.198 167.989 91.620  1.00 279.14 ? 594 TYR C CG  1 
ATOM   10520 C CD1 . TYR C 3 571 ? 200.828 168.106 91.813  1.00 279.14 ? 594 TYR C CD1 1 
ATOM   10521 C CD2 . TYR C 3 571 ? 202.829 166.843 92.089  1.00 279.14 ? 594 TYR C CD2 1 
ATOM   10522 C CE1 . TYR C 3 571 ? 200.107 167.113 92.450  1.00 279.14 ? 594 TYR C CE1 1 
ATOM   10523 C CE2 . TYR C 3 571 ? 202.117 165.845 92.727  1.00 279.14 ? 594 TYR C CE2 1 
ATOM   10524 C CZ  . TYR C 3 571 ? 200.756 165.985 92.904  1.00 279.14 ? 594 TYR C CZ  1 
ATOM   10525 O OH  . TYR C 3 571 ? 200.041 164.995 93.539  1.00 279.14 ? 594 TYR C OH  1 
ATOM   10526 N N   . ASN C 3 572 ? 203.073 170.855 87.881  1.00 279.54 ? 595 ASN C N   1 
ATOM   10527 C CA  . ASN C 3 572 ? 203.671 171.999 87.196  1.00 279.54 ? 595 ASN C CA  1 
ATOM   10528 C C   . ASN C 3 572 ? 203.499 173.226 88.081  1.00 279.54 ? 595 ASN C C   1 
ATOM   10529 O O   . ASN C 3 572 ? 202.425 173.830 88.127  1.00 279.54 ? 595 ASN C O   1 
ATOM   10530 C CB  . ASN C 3 572 ? 203.035 172.201 85.825  1.00 279.54 ? 595 ASN C CB  1 
ATOM   10531 C CG  . ASN C 3 572 ? 203.393 171.098 84.848  1.00 279.54 ? 595 ASN C CG  1 
ATOM   10532 O OD1 . ASN C 3 572 ? 203.816 170.013 85.247  1.00 279.54 ? 595 ASN C OD1 1 
ATOM   10533 N ND2 . ASN C 3 572 ? 203.223 171.370 83.560  1.00 279.54 ? 595 ASN C ND2 1 
ATOM   10534 N N   . PHE C 3 573 ? 204.562 173.596 88.790  1.00 276.91 ? 596 PHE C N   1 
ATOM   10535 C CA  . PHE C 3 573 ? 204.523 174.755 89.668  1.00 276.91 ? 596 PHE C CA  1 
ATOM   10536 C C   . PHE C 3 573 ? 204.697 176.036 88.863  1.00 276.91 ? 596 PHE C C   1 
ATOM   10537 O O   . PHE C 3 573 ? 205.519 176.104 87.945  1.00 276.91 ? 596 PHE C O   1 
ATOM   10538 C CB  . PHE C 3 573 ? 205.613 174.656 90.736  1.00 276.91 ? 596 PHE C CB  1 
ATOM   10539 C CG  . PHE C 3 573 ? 205.592 173.367 91.508  1.00 276.91 ? 596 PHE C CG  1 
ATOM   10540 C CD1 . PHE C 3 573 ? 204.759 173.216 92.604  1.00 276.91 ? 596 PHE C CD1 1 
ATOM   10541 C CD2 . PHE C 3 573 ? 206.407 172.310 91.141  1.00 276.91 ? 596 PHE C CD2 1 
ATOM   10542 C CE1 . PHE C 3 573 ? 204.737 172.033 93.318  1.00 276.91 ? 596 PHE C CE1 1 
ATOM   10543 C CE2 . PHE C 3 573 ? 206.390 171.124 91.851  1.00 276.91 ? 596 PHE C CE2 1 
ATOM   10544 C CZ  . PHE C 3 573 ? 205.553 170.985 92.941  1.00 276.91 ? 596 PHE C CZ  1 
ATOM   10545 N N   . ARG C 3 574 ? 203.914 177.053 89.214  1.00 272.48 ? 597 ARG C N   1 
ATOM   10546 C CA  . ARG C 3 574 ? 203.977 178.358 88.567  1.00 272.48 ? 597 ARG C CA  1 
ATOM   10547 C C   . ARG C 3 574 ? 204.115 179.421 89.644  1.00 272.48 ? 597 ARG C C   1 
ATOM   10548 O O   . ARG C 3 574 ? 203.269 179.514 90.539  1.00 272.48 ? 597 ARG C O   1 
ATOM   10549 C CB  . ARG C 3 574 ? 202.736 178.613 87.708  1.00 272.48 ? 597 ARG C CB  1 
ATOM   10550 C CG  . ARG C 3 574 ? 202.572 177.639 86.552  1.00 272.48 ? 597 ARG C CG  1 
ATOM   10551 C CD  . ARG C 3 574 ? 201.320 177.939 85.745  1.00 272.48 ? 597 ARG C CD  1 
ATOM   10552 N NE  . ARG C 3 574 ? 200.107 177.816 86.549  1.00 272.48 ? 597 ARG C NE  1 
ATOM   10553 C CZ  . ARG C 3 574 ? 198.880 178.031 86.087  1.00 272.48 ? 597 ARG C CZ  1 
ATOM   10554 N NH1 . ARG C 3 574 ? 198.697 178.382 84.821  1.00 272.48 ? 597 ARG C NH1 1 
ATOM   10555 N NH2 . ARG C 3 574 ? 197.833 177.896 86.890  1.00 272.48 ? 597 ARG C NH2 1 
ATOM   10556 N N   . ILE C 3 575 ? 205.176 180.217 89.559  1.00 270.65 ? 598 ILE C N   1 
ATOM   10557 C CA  . ILE C 3 575 ? 205.471 181.249 90.546  1.00 270.65 ? 598 ILE C CA  1 
ATOM   10558 C C   . ILE C 3 575 ? 205.016 182.589 89.987  1.00 270.65 ? 598 ILE C C   1 
ATOM   10559 O O   . ILE C 3 575 ? 205.454 183.003 88.906  1.00 270.65 ? 598 ILE C O   1 
ATOM   10560 C CB  . ILE C 3 575 ? 206.965 181.276 90.905  1.00 270.65 ? 598 ILE C CB  1 
ATOM   10561 C CG1 . ILE C 3 575 ? 207.365 179.997 91.648  1.00 270.65 ? 598 ILE C CG1 1 
ATOM   10562 C CG2 . ILE C 3 575 ? 207.289 182.505 91.740  1.00 270.65 ? 598 ILE C CG2 1 
ATOM   10563 C CD1 . ILE C 3 575 ? 207.873 178.888 90.749  1.00 270.65 ? 598 ILE C CD1 1 
ATOM   10564 N N   . PHE C 3 576 ? 204.139 183.268 90.722  1.00 268.72 ? 599 PHE C N   1 
ATOM   10565 C CA  . PHE C 3 576 ? 203.614 184.569 90.331  1.00 268.72 ? 599 PHE C CA  1 
ATOM   10566 C C   . PHE C 3 576 ? 204.040 185.609 91.355  1.00 268.72 ? 599 PHE C C   1 
ATOM   10567 O O   . PHE C 3 576 ? 203.915 185.384 92.564  1.00 268.72 ? 599 PHE C O   1 
ATOM   10568 C CB  . PHE C 3 576 ? 202.087 184.535 90.213  1.00 268.72 ? 599 PHE C CB  1 
ATOM   10569 C CG  . PHE C 3 576 ? 201.590 183.847 88.974  1.00 268.72 ? 599 PHE C CG  1 
ATOM   10570 C CD1 . PHE C 3 576 ? 201.312 184.571 87.827  1.00 268.72 ? 599 PHE C CD1 1 
ATOM   10571 C CD2 . PHE C 3 576 ? 201.399 182.475 88.958  1.00 268.72 ? 599 PHE C CD2 1 
ATOM   10572 C CE1 . PHE C 3 576 ? 200.853 183.941 86.686  1.00 268.72 ? 599 PHE C CE1 1 
ATOM   10573 C CE2 . PHE C 3 576 ? 200.941 181.838 87.819  1.00 268.72 ? 599 PHE C CE2 1 
ATOM   10574 C CZ  . PHE C 3 576 ? 200.668 182.572 86.682  1.00 268.72 ? 599 PHE C CZ  1 
ATOM   10575 N N   . GLU C 3 577 ? 204.542 186.741 90.872  1.00 266.22 ? 600 GLU C N   1 
ATOM   10576 C CA  . GLU C 3 577 ? 204.989 187.833 91.726  1.00 266.22 ? 600 GLU C CA  1 
ATOM   10577 C C   . GLU C 3 577 ? 203.951 188.946 91.719  1.00 266.22 ? 600 GLU C C   1 
ATOM   10578 O O   . GLU C 3 577 ? 203.513 189.387 90.651  1.00 266.22 ? 600 GLU C O   1 
ATOM   10579 C CB  . GLU C 3 577 ? 206.344 188.368 91.261  1.00 266.22 ? 600 GLU C CB  1 
ATOM   10580 C CG  . GLU C 3 577 ? 206.739 189.692 91.895  1.00 266.22 ? 600 GLU C CG  1 
ATOM   10581 C CD  . GLU C 3 577 ? 208.062 190.215 91.373  1.00 266.22 ? 600 GLU C CD  1 
ATOM   10582 O OE1 . GLU C 3 577 ? 208.962 189.393 91.101  1.00 266.22 ? 600 GLU C OE1 1 
ATOM   10583 O OE2 . GLU C 3 577 ? 208.202 191.449 91.233  1.00 266.22 ? 600 GLU C OE2 1 
ATOM   10584 N N   . ARG C 3 578 ? 203.561 189.395 92.908  1.00 262.84 ? 601 ARG C N   1 
ATOM   10585 C CA  . ARG C 3 578 ? 202.587 190.467 93.065  1.00 262.84 ? 601 ARG C CA  1 
ATOM   10586 C C   . ARG C 3 578 ? 203.323 191.776 93.321  1.00 262.84 ? 601 ARG C C   1 
ATOM   10587 O O   . ARG C 3 578 ? 204.108 191.877 94.270  1.00 262.84 ? 601 ARG C O   1 
ATOM   10588 C CB  . ARG C 3 578 ? 201.619 190.161 94.207  1.00 262.84 ? 601 ARG C CB  1 
ATOM   10589 C CG  . ARG C 3 578 ? 200.679 189.001 93.928  1.00 262.84 ? 601 ARG C CG  1 
ATOM   10590 C CD  . ARG C 3 578 ? 199.772 188.732 95.116  1.00 262.84 ? 601 ARG C CD  1 
ATOM   10591 N NE  . ARG C 3 578 ? 199.056 189.929 95.546  1.00 262.84 ? 601 ARG C NE  1 
ATOM   10592 C CZ  . ARG C 3 578 ? 198.215 189.967 96.573  1.00 262.84 ? 601 ARG C CZ  1 
ATOM   10593 N NH1 . ARG C 3 578 ? 197.980 188.870 97.281  1.00 262.84 ? 601 ARG C NH1 1 
ATOM   10594 N NH2 . ARG C 3 578 ? 197.606 191.100 96.894  1.00 262.84 ? 601 ARG C NH2 1 
ATOM   10595 N N   . SER C 3 579 ? 203.069 192.772 92.476  1.00 261.69 ? 602 SER C N   1 
ATOM   10596 C CA  . SER C 3 579 ? 203.700 194.077 92.614  1.00 261.69 ? 602 SER C CA  1 
ATOM   10597 C C   . SER C 3 579 ? 202.932 194.909 93.640  1.00 261.69 ? 602 SER C C   1 
ATOM   10598 O O   . SER C 3 579 ? 202.050 194.413 94.347  1.00 261.69 ? 602 SER C O   1 
ATOM   10599 C CB  . SER C 3 579 ? 203.780 194.770 91.256  1.00 261.69 ? 602 SER C CB  1 
ATOM   10600 O OG  . SER C 3 579 ? 202.559 194.648 90.548  1.00 261.69 ? 602 SER C OG  1 
ATOM   10601 N N   . VAL C 3 580 ? 203.264 196.199 93.733  1.00 263.12 ? 603 VAL C N   1 
ATOM   10602 C CA  . VAL C 3 580 ? 202.579 197.077 94.673  1.00 263.12 ? 603 VAL C CA  1 
ATOM   10603 C C   . VAL C 3 580 ? 201.151 197.371 94.232  1.00 263.12 ? 603 VAL C C   1 
ATOM   10604 O O   . VAL C 3 580 ? 200.310 197.725 95.067  1.00 263.12 ? 603 VAL C O   1 
ATOM   10605 C CB  . VAL C 3 580 ? 203.367 198.386 94.859  1.00 263.12 ? 603 VAL C CB  1 
ATOM   10606 C CG1 . VAL C 3 580 ? 204.600 198.144 95.715  1.00 263.12 ? 603 VAL C CG1 1 
ATOM   10607 C CG2 . VAL C 3 580 ? 203.754 198.970 93.509  1.00 263.12 ? 603 VAL C CG2 1 
ATOM   10608 N N   . GLU C 3 581 ? 200.853 197.234 92.941  1.00 265.46 ? 604 GLU C N   1 
ATOM   10609 C CA  . GLU C 3 581 ? 199.516 197.470 92.414  1.00 265.46 ? 604 GLU C CA  1 
ATOM   10610 C C   . GLU C 3 581 ? 198.667 196.203 92.375  1.00 265.46 ? 604 GLU C C   1 
ATOM   10611 O O   . GLU C 3 581 ? 197.694 196.146 91.613  1.00 265.46 ? 604 GLU C O   1 
ATOM   10612 C CB  . GLU C 3 581 ? 199.602 198.089 91.017  1.00 265.46 ? 604 GLU C CB  1 
ATOM   10613 C CG  . GLU C 3 581 ? 200.460 199.343 90.945  1.00 265.46 ? 604 GLU C CG  1 
ATOM   10614 C CD  . GLU C 3 581 ? 199.896 200.486 91.768  1.00 265.46 ? 604 GLU C CD  1 
ATOM   10615 O OE1 . GLU C 3 581 ? 198.657 200.577 91.894  1.00 265.46 ? 604 GLU C OE1 1 
ATOM   10616 O OE2 . GLU C 3 581 ? 200.693 201.293 92.290  1.00 265.46 ? 604 GLU C OE2 1 
ATOM   10617 N N   . HIS C 3 582 ? 199.018 195.193 93.174  1.00 264.16 ? 605 HIS C N   1 
ATOM   10618 C CA  . HIS C 3 582 ? 198.279 193.931 93.246  1.00 264.16 ? 605 HIS C CA  1 
ATOM   10619 C C   . HIS C 3 582 ? 198.188 193.243 91.886  1.00 264.16 ? 605 HIS C C   1 
ATOM   10620 O O   . HIS C 3 582 ? 197.194 192.583 91.576  1.00 264.16 ? 605 HIS C O   1 
ATOM   10621 C CB  . HIS C 3 582 ? 196.880 194.138 93.835  1.00 264.16 ? 605 HIS C CB  1 
ATOM   10622 C CG  . HIS C 3 582 ? 196.886 194.621 95.252  1.00 264.16 ? 605 HIS C CG  1 
ATOM   10623 N ND1 . HIS C 3 582 ? 197.364 195.862 95.613  1.00 264.16 ? 605 HIS C ND1 1 
ATOM   10624 C CD2 . HIS C 3 582 ? 196.471 194.030 96.397  1.00 264.16 ? 605 HIS C CD2 1 
ATOM   10625 C CE1 . HIS C 3 582 ? 197.245 196.014 96.920  1.00 264.16 ? 605 HIS C CE1 1 
ATOM   10626 N NE2 . HIS C 3 582 ? 196.706 194.917 97.420  1.00 264.16 ? 605 HIS C NE2 1 
ATOM   10627 N N   . LYS C 3 583 ? 199.224 193.392 91.065  1.00 258.79 ? 606 LYS C N   1 
ATOM   10628 C CA  . LYS C 3 583 ? 199.277 192.782 89.744  1.00 258.79 ? 606 LYS C CA  1 
ATOM   10629 C C   . LYS C 3 583 ? 200.166 191.546 89.789  1.00 258.79 ? 606 LYS C C   1 
ATOM   10630 O O   . LYS C 3 583 ? 201.320 191.620 90.224  1.00 258.79 ? 606 LYS C O   1 
ATOM   10631 C CB  . LYS C 3 583 ? 199.802 193.775 88.706  1.00 258.79 ? 606 LYS C CB  1 
ATOM   10632 C CG  . LYS C 3 583 ? 199.798 193.246 87.282  1.00 258.79 ? 606 LYS C CG  1 
ATOM   10633 C CD  . LYS C 3 583 ? 200.434 194.241 86.325  1.00 258.79 ? 606 LYS C CD  1 
ATOM   10634 C CE  . LYS C 3 583 ? 201.901 194.460 86.652  1.00 258.79 ? 606 LYS C CE  1 
ATOM   10635 N NZ  . LYS C 3 583 ? 202.674 193.189 86.604  1.00 258.79 ? 606 LYS C NZ  1 
ATOM   10636 N N   . ALA C 3 584 ? 199.627 190.416 89.337  1.00 259.99 ? 607 ALA C N   1 
ATOM   10637 C CA  . ALA C 3 584 ? 200.356 189.155 89.339  1.00 259.99 ? 607 ALA C CA  1 
ATOM   10638 C C   . ALA C 3 584 ? 201.016 188.934 87.984  1.00 259.99 ? 607 ALA C C   1 
ATOM   10639 O O   . ALA C 3 584 ? 200.351 188.993 86.944  1.00 259.99 ? 607 ALA C O   1 
ATOM   10640 C CB  . ALA C 3 584 ? 199.420 187.992 89.670  1.00 259.99 ? 607 ALA C CB  1 
ATOM   10641 N N   . ARG C 3 585 ? 202.321 188.678 88.001  1.00 263.23 ? 608 ARG C N   1 
ATOM   10642 C CA  . ARG C 3 585 ? 203.098 188.440 86.793  1.00 263.23 ? 608 ARG C CA  1 
ATOM   10643 C C   . ARG C 3 585 ? 203.796 187.091 86.889  1.00 263.23 ? 608 ARG C C   1 
ATOM   10644 O O   . ARG C 3 585 ? 204.299 186.715 87.952  1.00 263.23 ? 608 ARG C O   1 
ATOM   10645 C CB  . ARG C 3 585 ? 204.129 189.553 86.568  1.00 263.23 ? 608 ARG C CB  1 
ATOM   10646 C CG  . ARG C 3 585 ? 205.028 189.822 87.765  1.00 263.23 ? 608 ARG C CG  1 
ATOM   10647 C CD  . ARG C 3 585 ? 206.084 190.868 87.444  1.00 263.23 ? 608 ARG C CD  1 
ATOM   10648 N NE  . ARG C 3 585 ? 205.491 192.155 87.092  1.00 263.23 ? 608 ARG C NE  1 
ATOM   10649 C CZ  . ARG C 3 585 ? 206.192 193.242 86.789  1.00 263.23 ? 608 ARG C CZ  1 
ATOM   10650 N NH1 . ARG C 3 585 ? 207.517 193.201 86.793  1.00 263.23 ? 608 ARG C NH1 1 
ATOM   10651 N NH2 . ARG C 3 585 ? 205.569 194.371 86.481  1.00 263.23 ? 608 ARG C NH2 1 
ATOM   10652 N N   . LEU C 3 586 ? 203.823 186.365 85.773  1.00 268.77 ? 609 LEU C N   1 
ATOM   10653 C CA  . LEU C 3 586 ? 204.475 185.063 85.723  1.00 268.77 ? 609 LEU C CA  1 
ATOM   10654 C C   . LEU C 3 586 ? 205.973 185.258 85.520  1.00 268.77 ? 609 LEU C C   1 
ATOM   10655 O O   . LEU C 3 586 ? 206.397 185.887 84.545  1.00 268.77 ? 609 LEU C O   1 
ATOM   10656 C CB  . LEU C 3 586 ? 203.882 184.213 84.602  1.00 268.77 ? 609 LEU C CB  1 
ATOM   10657 C CG  . LEU C 3 586 ? 204.420 182.789 84.446  1.00 268.77 ? 609 LEU C CG  1 
ATOM   10658 C CD1 . LEU C 3 586 ? 204.547 182.101 85.799  1.00 268.77 ? 609 LEU C CD1 1 
ATOM   10659 C CD2 . LEU C 3 586 ? 203.530 181.983 83.513  1.00 268.77 ? 609 LEU C CD2 1 
ATOM   10660 N N   . VAL C 3 587 ? 206.775 184.718 86.441  1.00 266.63 ? 610 VAL C N   1 
ATOM   10661 C CA  . VAL C 3 587 ? 208.220 184.886 86.419  1.00 266.63 ? 610 VAL C CA  1 
ATOM   10662 C C   . VAL C 3 587 ? 208.948 183.561 86.225  1.00 266.63 ? 610 VAL C C   1 
ATOM   10663 O O   . VAL C 3 587 ? 209.936 183.496 85.484  1.00 266.63 ? 610 VAL C O   1 
ATOM   10664 C CB  . VAL C 3 587 ? 208.715 185.600 87.699  1.00 266.63 ? 610 VAL C CB  1 
ATOM   10665 C CG1 . VAL C 3 587 ? 208.212 184.889 88.950  1.00 266.63 ? 610 VAL C CG1 1 
ATOM   10666 C CG2 . VAL C 3 587 ? 210.234 185.705 87.707  1.00 266.63 ? 610 VAL C CG2 1 
ATOM   10667 N N   . GLU C 3 588 ? 208.476 182.491 86.861  1.00 271.56 ? 611 GLU C N   1 
ATOM   10668 C CA  . GLU C 3 588 ? 209.169 181.212 86.823  1.00 271.56 ? 611 GLU C CA  1 
ATOM   10669 C C   . GLU C 3 588 ? 208.160 180.073 86.795  1.00 271.56 ? 611 GLU C C   1 
ATOM   10670 O O   . GLU C 3 588 ? 207.075 180.166 87.376  1.00 271.56 ? 611 GLU C O   1 
ATOM   10671 C CB  . GLU C 3 588 ? 210.108 181.048 88.027  1.00 271.56 ? 611 GLU C CB  1 
ATOM   10672 C CG  . GLU C 3 588 ? 211.109 179.913 87.889  1.00 271.56 ? 611 GLU C CG  1 
ATOM   10673 C CD  . GLU C 3 588 ? 211.753 179.538 89.209  1.00 271.56 ? 611 GLU C CD  1 
ATOM   10674 O OE1 . GLU C 3 588 ? 211.037 179.501 90.231  1.00 271.56 ? 611 GLU C OE1 1 
ATOM   10675 O OE2 . GLU C 3 588 ? 212.975 179.280 89.224  1.00 271.56 ? 611 GLU C OE2 1 
ATOM   10676 N N   . LYS C 3 589 ? 208.534 178.995 86.108  1.00 275.23 ? 612 LYS C N   1 
ATOM   10677 C CA  . LYS C 3 589 ? 207.743 177.774 86.046  1.00 275.23 ? 612 LYS C CA  1 
ATOM   10678 C C   . LYS C 3 589 ? 208.610 176.608 86.494  1.00 275.23 ? 612 LYS C C   1 
ATOM   10679 O O   . LYS C 3 589 ? 209.766 176.494 86.074  1.00 275.23 ? 612 LYS C O   1 
ATOM   10680 C CB  . LYS C 3 589 ? 207.209 177.524 84.631  1.00 275.23 ? 612 LYS C CB  1 
ATOM   10681 C CG  . LYS C 3 589 ? 205.937 178.286 84.297  1.00 275.23 ? 612 LYS C CG  1 
ATOM   10682 C CD  . LYS C 3 589 ? 205.365 177.832 82.963  1.00 275.23 ? 612 LYS C CD  1 
ATOM   10683 C CE  . LYS C 3 589 ? 203.982 178.416 82.727  1.00 275.23 ? 612 LYS C CE  1 
ATOM   10684 N NZ  . LYS C 3 589 ? 203.407 177.973 81.427  1.00 275.23 ? 612 LYS C NZ  1 
ATOM   10685 N N   . GLN C 3 590 ? 208.054 175.746 87.342  1.00 275.68 ? 613 GLN C N   1 
ATOM   10686 C CA  . GLN C 3 590 ? 208.775 174.601 87.874  1.00 275.68 ? 613 GLN C CA  1 
ATOM   10687 C C   . GLN C 3 590 ? 207.919 173.349 87.747  1.00 275.68 ? 613 GLN C C   1 
ATOM   10688 O O   . GLN C 3 590 ? 206.694 173.416 87.622  1.00 275.68 ? 613 GLN C O   1 
ATOM   10689 C CB  . GLN C 3 590 ? 209.173 174.816 89.342  1.00 275.68 ? 613 GLN C CB  1 
ATOM   10690 C CG  . GLN C 3 590 ? 210.152 175.958 89.562  1.00 275.68 ? 613 GLN C CG  1 
ATOM   10691 C CD  . GLN C 3 590 ? 210.535 176.123 91.020  1.00 275.68 ? 613 GLN C CD  1 
ATOM   10692 O OE1 . GLN C 3 590 ? 210.072 175.377 91.883  1.00 275.68 ? 613 GLN C OE1 1 
ATOM   10693 N NE2 . GLN C 3 590 ? 211.385 177.103 91.302  1.00 275.68 ? 613 GLN C NE2 1 
ATOM   10694 N N   . ARG C 3 591 ? 208.587 172.198 87.779  1.00 276.03 ? 614 ARG C N   1 
ATOM   10695 C CA  . ARG C 3 591 ? 207.911 170.912 87.700  1.00 276.03 ? 614 ARG C CA  1 
ATOM   10696 C C   . ARG C 3 591 ? 208.794 169.850 88.338  1.00 276.03 ? 614 ARG C C   1 
ATOM   10697 O O   . ARG C 3 591 ? 210.024 169.946 88.310  1.00 276.03 ? 614 ARG C O   1 
ATOM   10698 C CB  . ARG C 3 591 ? 207.582 170.532 86.251  1.00 276.03 ? 614 ARG C CB  1 
ATOM   10699 C CG  . ARG C 3 591 ? 208.790 170.474 85.332  1.00 276.03 ? 614 ARG C CG  1 
ATOM   10700 C CD  . ARG C 3 591 ? 208.379 170.176 83.899  1.00 276.03 ? 614 ARG C CD  1 
ATOM   10701 N NE  . ARG C 3 591 ? 209.529 170.122 83.001  1.00 276.03 ? 614 ARG C NE  1 
ATOM   10702 C CZ  . ARG C 3 591 ? 209.445 169.904 81.693  1.00 276.03 ? 614 ARG C CZ  1 
ATOM   10703 N NH1 . ARG C 3 591 ? 208.262 169.718 81.124  1.00 276.03 ? 614 ARG C NH1 1 
ATOM   10704 N NH2 . ARG C 3 591 ? 210.545 169.871 80.952  1.00 276.03 ? 614 ARG C NH2 1 
ATOM   10705 N N   . GLY C 3 592 ? 208.155 168.841 88.915  1.00 276.44 ? 615 GLY C N   1 
ATOM   10706 C CA  . GLY C 3 592 ? 208.890 167.766 89.557  1.00 276.44 ? 615 GLY C CA  1 
ATOM   10707 C C   . GLY C 3 592 ? 207.936 166.716 90.080  1.00 276.44 ? 615 GLY C C   1 
ATOM   10708 O O   . GLY C 3 592 ? 206.711 166.881 90.055  1.00 276.44 ? 615 GLY C O   1 
ATOM   10709 N N   . TYR C 3 593 ? 208.524 165.623 90.559  1.00 274.03 ? 616 TYR C N   1 
ATOM   10710 C CA  . TYR C 3 593 ? 207.780 164.506 91.118  1.00 274.03 ? 616 TYR C CA  1 
ATOM   10711 C C   . TYR C 3 593 ? 208.133 164.336 92.589  1.00 274.03 ? 616 TYR C C   1 
ATOM   10712 O O   . TYR C 3 593 ? 209.257 164.624 93.013  1.00 274.03 ? 616 TYR C O   1 
ATOM   10713 C CB  . TYR C 3 593 ? 208.075 163.202 90.364  1.00 274.03 ? 616 TYR C CB  1 
ATOM   10714 C CG  . TYR C 3 593 ? 207.612 163.198 88.925  1.00 274.03 ? 616 TYR C CG  1 
ATOM   10715 C CD1 . TYR C 3 593 ? 206.392 162.639 88.570  1.00 274.03 ? 616 TYR C CD1 1 
ATOM   10716 C CD2 . TYR C 3 593 ? 208.397 163.749 87.921  1.00 274.03 ? 616 TYR C CD2 1 
ATOM   10717 C CE1 . TYR C 3 593 ? 205.965 162.630 87.256  1.00 274.03 ? 616 TYR C CE1 1 
ATOM   10718 C CE2 . TYR C 3 593 ? 207.978 163.746 86.604  1.00 274.03 ? 616 TYR C CE2 1 
ATOM   10719 C CZ  . TYR C 3 593 ? 206.762 163.185 86.277  1.00 274.03 ? 616 TYR C CZ  1 
ATOM   10720 O OH  . TYR C 3 593 ? 206.341 163.180 84.967  1.00 274.03 ? 616 TYR C OH  1 
ATOM   10721 N N   . THR C 3 594 ? 207.157 163.867 93.368  1.00 270.79 ? 617 THR C N   1 
ATOM   10722 C CA  . THR C 3 594 ? 207.409 163.584 94.777  1.00 270.79 ? 617 THR C CA  1 
ATOM   10723 C C   . THR C 3 594 ? 208.360 162.404 94.931  1.00 270.79 ? 617 THR C C   1 
ATOM   10724 O O   . THR C 3 594 ? 209.297 162.448 95.738  1.00 270.79 ? 617 THR C O   1 
ATOM   10725 C CB  . THR C 3 594 ? 206.091 163.311 95.503  1.00 270.79 ? 617 THR C CB  1 
ATOM   10726 O OG1 . THR C 3 594 ? 205.561 162.050 95.076  1.00 270.79 ? 617 THR C OG1 1 
ATOM   10727 C CG2 . THR C 3 594 ? 205.082 164.405 95.195  1.00 270.79 ? 617 THR C CG2 1 
ATOM   10728 N N   . GLN C 3 595 ? 208.133 161.341 94.164  1.00 268.88 ? 618 GLN C N   1 
ATOM   10729 C CA  . GLN C 3 595 ? 209.013 160.175 94.171  1.00 268.88 ? 618 GLN C CA  1 
ATOM   10730 C C   . GLN C 3 595 ? 208.923 159.528 92.797  1.00 268.88 ? 618 GLN C C   1 
ATOM   10731 O O   . GLN C 3 595 ? 207.886 158.956 92.448  1.00 268.88 ? 618 GLN C O   1 
ATOM   10732 C CB  . GLN C 3 595 ? 208.623 159.192 95.271  1.00 268.88 ? 618 GLN C CB  1 
ATOM   10733 C CG  . GLN C 3 595 ? 209.523 157.970 95.359  1.00 268.88 ? 618 GLN C CG  1 
ATOM   10734 C CD  . GLN C 3 595 ? 209.103 157.016 96.460  1.00 268.88 ? 618 GLN C CD  1 
ATOM   10735 O OE1 . GLN C 3 595 ? 208.104 157.240 97.144  1.00 268.88 ? 618 GLN C OE1 1 
ATOM   10736 N NE2 . GLN C 3 595 ? 209.866 155.943 96.636  1.00 268.88 ? 618 GLN C NE2 1 
ATOM   10737 N N   . GLU C 3 596 ? 209.998 159.627 92.019  1.00 269.34 ? 619 GLU C N   1 
ATOM   10738 C CA  . GLU C 3 596 ? 210.003 159.070 90.673  1.00 269.34 ? 619 GLU C CA  1 
ATOM   10739 C C   . GLU C 3 596 ? 209.976 157.548 90.730  1.00 269.34 ? 619 GLU C C   1 
ATOM   10740 O O   . GLU C 3 596 ? 210.743 156.929 91.475  1.00 269.34 ? 619 GLU C O   1 
ATOM   10741 C CB  . GLU C 3 596 ? 211.231 159.554 89.905  1.00 269.34 ? 619 GLU C CB  1 
ATOM   10742 C CG  . GLU C 3 596 ? 211.214 161.041 89.584  1.00 269.34 ? 619 GLU C CG  1 
ATOM   10743 C CD  . GLU C 3 596 ? 212.513 161.520 88.966  1.00 269.34 ? 619 GLU C CD  1 
ATOM   10744 O OE1 . GLU C 3 596 ? 213.572 160.935 89.278  1.00 269.34 ? 619 GLU C OE1 1 
ATOM   10745 O OE2 . GLU C 3 596 ? 212.476 162.481 88.170  1.00 269.34 ? 619 GLU C OE2 1 
ATOM   10746 N N   . LEU C 3 597 ? 209.091 156.947 89.943  1.00 268.38 ? 620 LEU C N   1 
ATOM   10747 C CA  . LEU C 3 597 ? 208.920 155.502 89.883  1.00 268.38 ? 620 LEU C CA  1 
ATOM   10748 C C   . LEU C 3 597 ? 209.271 155.000 88.485  1.00 268.38 ? 620 LEU C C   1 
ATOM   10749 O O   . LEU C 3 597 ? 209.631 155.770 87.592  1.00 268.38 ? 620 LEU C O   1 
ATOM   10750 C CB  . LEU C 3 597 ? 207.490 155.104 90.261  1.00 268.38 ? 620 LEU C CB  1 
ATOM   10751 C CG  . LEU C 3 597 ? 206.835 155.844 91.428  1.00 268.38 ? 620 LEU C CG  1 
ATOM   10752 C CD1 . LEU C 3 597 ? 205.435 155.309 91.676  1.00 268.38 ? 620 LEU C CD1 1 
ATOM   10753 C CD2 . LEU C 3 597 ? 207.682 155.716 92.684  1.00 268.38 ? 620 LEU C CD2 1 
ATOM   10754 N N   . ALA C 3 598 ? 209.160 153.687 88.306  1.00 270.94 ? 621 ALA C N   1 
ATOM   10755 C CA  . ALA C 3 598 ? 209.454 153.082 87.019  1.00 270.94 ? 621 ALA C CA  1 
ATOM   10756 C C   . ALA C 3 598 ? 208.352 153.411 86.012  1.00 270.94 ? 621 ALA C C   1 
ATOM   10757 O O   . ALA C 3 598 ? 207.198 153.630 86.393  1.00 270.94 ? 621 ALA C O   1 
ATOM   10758 C CB  . ALA C 3 598 ? 209.594 151.569 87.161  1.00 270.94 ? 621 ALA C CB  1 
ATOM   10759 N N   . PRO C 3 599 ? 208.685 153.467 84.722  1.00 275.11 ? 622 PRO C N   1 
ATOM   10760 C CA  . PRO C 3 599 ? 207.656 153.731 83.710  1.00 275.11 ? 622 PRO C CA  1 
ATOM   10761 C C   . PRO C 3 599 ? 206.605 152.632 83.685  1.00 275.11 ? 622 PRO C C   1 
ATOM   10762 O O   . PRO C 3 599 ? 206.867 151.480 84.036  1.00 275.11 ? 622 PRO C O   1 
ATOM   10763 C CB  . PRO C 3 599 ? 208.449 153.778 82.398  1.00 275.11 ? 622 PRO C CB  1 
ATOM   10764 C CG  . PRO C 3 599 ? 209.855 154.071 82.809  1.00 275.11 ? 622 PRO C CG  1 
ATOM   10765 C CD  . PRO C 3 599 ? 210.034 153.400 84.135  1.00 275.11 ? 622 PRO C CD  1 
ATOM   10766 N N   . LEU C 3 600 ? 205.396 153.006 83.261  1.00 269.59 ? 623 LEU C N   1 
ATOM   10767 C CA  . LEU C 3 600 ? 204.267 152.086 83.236  1.00 269.59 ? 623 LEU C CA  1 
ATOM   10768 C C   . LEU C 3 600 ? 203.873 151.630 81.840  1.00 269.59 ? 623 LEU C C   1 
ATOM   10769 O O   . LEU C 3 600 ? 203.178 150.617 81.717  1.00 269.59 ? 623 LEU C O   1 
ATOM   10770 C CB  . LEU C 3 600 ? 203.040 152.721 83.910  1.00 269.59 ? 623 LEU C CB  1 
ATOM   10771 C CG  . LEU C 3 600 ? 202.265 153.808 83.156  1.00 269.59 ? 623 LEU C CG  1 
ATOM   10772 C CD1 . LEU C 3 600 ? 200.886 153.991 83.772  1.00 269.59 ? 623 LEU C CD1 1 
ATOM   10773 C CD2 . LEU C 3 600 ? 203.016 155.132 83.144  1.00 269.59 ? 623 LEU C CD2 1 
ATOM   10774 N N   . VAL C 3 601 ? 204.292 152.339 80.795  1.00 269.19 ? 624 VAL C N   1 
ATOM   10775 C CA  . VAL C 3 601 ? 203.933 151.999 79.424  1.00 269.19 ? 624 VAL C CA  1 
ATOM   10776 C C   . VAL C 3 601 ? 205.182 152.079 78.557  1.00 269.19 ? 624 VAL C C   1 
ATOM   10777 O O   . VAL C 3 601 ? 205.997 152.997 78.703  1.00 269.19 ? 624 VAL C O   1 
ATOM   10778 C CB  . VAL C 3 601 ? 202.815 152.921 78.886  1.00 269.19 ? 624 VAL C CB  1 
ATOM   10779 C CG1 . VAL C 3 601 ? 203.201 154.387 79.039  1.00 269.19 ? 624 VAL C CG1 1 
ATOM   10780 C CG2 . VAL C 3 601 ? 202.489 152.591 77.435  1.00 269.19 ? 624 VAL C CG2 1 
ATOM   10781 N N   . ASN C 3 602 ? 205.339 151.104 77.662  1.00 278.93 ? 625 ASN C N   1 
ATOM   10782 C CA  . ASN C 3 602 ? 206.459 151.063 76.733  1.00 278.93 ? 625 ASN C CA  1 
ATOM   10783 C C   . ASN C 3 602 ? 206.038 151.586 75.365  1.00 278.93 ? 625 ASN C C   1 
ATOM   10784 O O   . ASN C 3 602 ? 204.900 151.361 74.938  1.00 278.93 ? 625 ASN C O   1 
ATOM   10785 C CB  . ASN C 3 602 ? 206.991 149.637 76.587  1.00 278.93 ? 625 ASN C CB  1 
ATOM   10786 C CG  . ASN C 3 602 ? 207.412 149.033 77.912  1.00 278.93 ? 625 ASN C CG  1 
ATOM   10787 O OD1 . ASN C 3 602 ? 207.791 149.747 78.840  1.00 278.93 ? 625 ASN C OD1 1 
ATOM   10788 N ND2 . ASN C 3 602 ? 207.346 147.710 78.007  1.00 278.93 ? 625 ASN C ND2 1 
ATOM   10789 N N   . PRO C 3 603 ? 206.925 152.285 74.661  1.00 287.12 ? 626 PRO C N   1 
ATOM   10790 C CA  . PRO C 3 603 ? 206.561 152.812 73.342  1.00 287.12 ? 626 PRO C CA  1 
ATOM   10791 C C   . PRO C 3 603 ? 206.488 151.711 72.297  1.00 287.12 ? 626 PRO C C   1 
ATOM   10792 O O   . PRO C 3 603 ? 207.224 150.723 72.344  1.00 287.12 ? 626 PRO C O   1 
ATOM   10793 C CB  . PRO C 3 603 ? 207.691 153.800 73.032  1.00 287.12 ? 626 PRO C CB  1 
ATOM   10794 C CG  . PRO C 3 603 ? 208.856 153.282 73.805  1.00 287.12 ? 626 PRO C CG  1 
ATOM   10795 C CD  . PRO C 3 603 ? 208.290 152.671 75.059  1.00 287.12 ? 626 PRO C CD  1 
ATOM   10796 N N   . LYS C 3 604 ? 205.579 151.896 71.342  1.00 289.47 ? 627 LYS C N   1 
ATOM   10797 C CA  . LYS C 3 604 ? 205.417 150.932 70.262  1.00 289.47 ? 627 LYS C CA  1 
ATOM   10798 C C   . LYS C 3 604 ? 206.587 151.033 69.291  1.00 289.47 ? 627 LYS C C   1 
ATOM   10799 O O   . LYS C 3 604 ? 206.930 152.124 68.826  1.00 289.47 ? 627 LYS C O   1 
ATOM   10800 C CB  . LYS C 3 604 ? 204.096 151.170 69.532  1.00 289.47 ? 627 LYS C CB  1 
ATOM   10801 C CG  . LYS C 3 604 ? 203.742 150.098 68.512  1.00 289.47 ? 627 LYS C CG  1 
ATOM   10802 C CD  . LYS C 3 604 ? 204.021 150.566 67.091  1.00 289.47 ? 627 LYS C CD  1 
ATOM   10803 C CE  . LYS C 3 604 ? 203.228 151.818 66.754  1.00 289.47 ? 627 LYS C CE  1 
ATOM   10804 N NZ  . LYS C 3 604 ? 203.511 152.298 65.373  1.00 289.47 ? 627 LYS C NZ  1 
ATOM   10805 N N   . VAL C 3 605 ? 207.196 149.892 68.981  1.00 293.36 ? 628 VAL C N   1 
ATOM   10806 C CA  . VAL C 3 605 ? 208.353 149.838 68.097  1.00 293.36 ? 628 VAL C CA  1 
ATOM   10807 C C   . VAL C 3 605 ? 207.895 149.446 66.700  1.00 293.36 ? 628 VAL C C   1 
ATOM   10808 O O   . VAL C 3 605 ? 206.919 148.707 66.520  1.00 293.36 ? 628 VAL C O   1 
ATOM   10809 C CB  . VAL C 3 605 ? 209.426 148.864 68.638  1.00 293.36 ? 628 VAL C CB  1 
ATOM   10810 C CG1 . VAL C 3 605 ? 208.974 147.417 68.492  1.00 293.36 ? 628 VAL C CG1 1 
ATOM   10811 C CG2 . VAL C 3 605 ? 210.762 149.093 67.942  1.00 293.36 ? 628 VAL C CG2 1 
ATOM   10812 N N   . GLU C 3 606 ? 208.596 149.967 65.695  1.00 293.78 ? 629 GLU C N   1 
ATOM   10813 C CA  . GLU C 3 606 ? 208.303 149.668 64.301  1.00 293.78 ? 629 GLU C CA  1 
ATOM   10814 C C   . GLU C 3 606 ? 209.598 149.736 63.507  1.00 293.78 ? 629 GLU C C   1 
ATOM   10815 O O   . GLU C 3 606 ? 210.387 150.669 63.676  1.00 293.78 ? 629 GLU C O   1 
ATOM   10816 C CB  . GLU C 3 606 ? 207.267 150.640 63.722  1.00 293.78 ? 629 GLU C CB  1 
ATOM   10817 C CG  . GLU C 3 606 ? 206.914 150.380 62.265  1.00 293.78 ? 629 GLU C CG  1 
ATOM   10818 C CD  . GLU C 3 606 ? 206.114 149.107 62.074  1.00 293.78 ? 629 GLU C CD  1 
ATOM   10819 O OE1 . GLU C 3 606 ? 205.428 148.682 63.028  1.00 293.78 ? 629 GLU C OE1 1 
ATOM   10820 O OE2 . GLU C 3 606 ? 206.169 148.529 60.967  1.00 293.78 ? 629 GLU C OE2 1 
ATOM   10821 N N   . ILE C 3 607 ? 209.808 148.749 62.644  1.00 290.78 ? 630 ILE C N   1 
ATOM   10822 C CA  . ILE C 3 607 ? 211.038 148.634 61.867  1.00 290.78 ? 630 ILE C CA  1 
ATOM   10823 C C   . ILE C 3 607 ? 210.846 149.380 60.547  1.00 290.78 ? 630 ILE C C   1 
ATOM   10824 O O   . ILE C 3 607 ? 209.894 149.075 59.810  1.00 290.78 ? 630 ILE C O   1 
ATOM   10825 C CB  . ILE C 3 607 ? 211.429 147.166 61.641  1.00 290.78 ? 630 ILE C CB  1 
ATOM   10826 C CG1 . ILE C 3 607 ? 212.825 147.062 61.018  1.00 290.78 ? 630 ILE C CG1 1 
ATOM   10827 C CG2 . ILE C 3 607 ? 210.363 146.382 60.864  1.00 290.78 ? 630 ILE C CG2 1 
ATOM   10828 C CD1 . ILE C 3 607 ? 213.526 145.754 61.309  1.00 290.78 ? 630 ILE C CD1 1 
ATOM   10829 N N   . PRO C 3 608 ? 211.667 150.390 60.245  1.00 286.91 ? 631 PRO C N   1 
ATOM   10830 C CA  . PRO C 3 608 ? 211.548 151.077 58.952  1.00 286.91 ? 631 PRO C CA  1 
ATOM   10831 C C   . PRO C 3 608 ? 212.241 150.339 57.817  1.00 286.91 ? 631 PRO C C   1 
ATOM   10832 O O   . PRO C 3 608 ? 211.770 150.361 56.675  1.00 286.91 ? 631 PRO C O   1 
ATOM   10833 C CB  . PRO C 3 608 ? 212.206 152.435 59.221  1.00 286.91 ? 631 PRO C CB  1 
ATOM   10834 C CG  . PRO C 3 608 ? 213.210 152.150 60.285  1.00 286.91 ? 631 PRO C CG  1 
ATOM   10835 C CD  . PRO C 3 608 ? 212.630 151.053 61.142  1.00 286.91 ? 631 PRO C CD  1 
ATOM   10836 N N   . TYR C 3 609 ? 213.359 149.682 58.119  1.00 290.63 ? 632 TYR C N   1 
ATOM   10837 C CA  . TYR C 3 609 ? 214.165 149.027 57.099  1.00 290.63 ? 632 TYR C CA  1 
ATOM   10838 C C   . TYR C 3 609 ? 214.813 147.786 57.693  1.00 290.63 ? 632 TYR C C   1 
ATOM   10839 O O   . TYR C 3 609 ? 215.131 147.745 58.885  1.00 290.63 ? 632 TYR C O   1 
ATOM   10840 C CB  . TYR C 3 609 ? 215.237 149.972 56.543  1.00 290.63 ? 632 TYR C CB  1 
ATOM   10841 C CG  . TYR C 3 609 ? 215.649 149.674 55.119  1.00 290.63 ? 632 TYR C CG  1 
ATOM   10842 C CD1 . TYR C 3 609 ? 215.030 150.306 54.049  1.00 290.63 ? 632 TYR C CD1 1 
ATOM   10843 C CD2 . TYR C 3 609 ? 216.662 148.764 54.845  1.00 290.63 ? 632 TYR C CD2 1 
ATOM   10844 C CE1 . TYR C 3 609 ? 215.405 150.039 52.746  1.00 290.63 ? 632 TYR C CE1 1 
ATOM   10845 C CE2 . TYR C 3 609 ? 217.044 148.490 53.545  1.00 290.63 ? 632 TYR C CE2 1 
ATOM   10846 C CZ  . TYR C 3 609 ? 216.412 149.130 52.500  1.00 290.63 ? 632 TYR C CZ  1 
ATOM   10847 O OH  . TYR C 3 609 ? 216.789 148.860 51.204  1.00 290.63 ? 632 TYR C OH  1 
ATOM   10848 N N   . SER C 3 610 ? 215.013 146.778 56.847  1.00 301.81 ? 633 SER C N   1 
ATOM   10849 C CA  . SER C 3 610 ? 215.596 145.510 57.273  1.00 301.81 ? 633 SER C CA  1 
ATOM   10850 C C   . SER C 3 610 ? 216.619 145.064 56.241  1.00 301.81 ? 633 SER C C   1 
ATOM   10851 O O   . SER C 3 610 ? 216.267 144.809 55.085  1.00 301.81 ? 633 SER C O   1 
ATOM   10852 C CB  . SER C 3 610 ? 214.516 144.439 57.457  1.00 301.81 ? 633 SER C CB  1 
ATOM   10853 O OG  . SER C 3 610 ? 215.073 143.138 57.393  1.00 301.81 ? 633 SER C OG  1 
ATOM   10854 N N   . THR C 3 611 ? 217.875 144.969 56.658  1.00 311.41 ? 634 THR C N   1 
ATOM   10855 C CA  . THR C 3 611 ? 218.965 144.490 55.827  1.00 311.41 ? 634 THR C CA  1 
ATOM   10856 C C   . THR C 3 611 ? 219.451 143.134 56.321  1.00 311.41 ? 634 THR C C   1 
ATOM   10857 O O   . THR C 3 611 ? 219.286 142.795 57.498  1.00 311.41 ? 634 THR C O   1 
ATOM   10858 C CB  . THR C 3 611 ? 220.134 145.487 55.831  1.00 311.41 ? 634 THR C CB  1 
ATOM   10859 O OG1 . THR C 3 611 ? 220.821 145.417 57.086  1.00 311.41 ? 634 THR C OG1 1 
ATOM   10860 C CG2 . THR C 3 611 ? 219.628 146.904 55.615  1.00 311.41 ? 634 THR C CG2 1 
ATOM   10861 N N   . PRO C 3 612 ? 220.049 142.320 55.444  1.00 313.15 ? 635 PRO C N   1 
ATOM   10862 C CA  . PRO C 3 612 ? 220.542 141.003 55.883  1.00 313.15 ? 635 PRO C CA  1 
ATOM   10863 C C   . PRO C 3 612 ? 221.644 141.070 56.931  1.00 313.15 ? 635 PRO C C   1 
ATOM   10864 O O   . PRO C 3 612 ? 221.947 140.038 57.543  1.00 313.15 ? 635 PRO C O   1 
ATOM   10865 C CB  . PRO C 3 612 ? 221.054 140.367 54.582  1.00 313.15 ? 635 PRO C CB  1 
ATOM   10866 C CG  . PRO C 3 612 ? 220.326 141.085 53.495  1.00 313.15 ? 635 PRO C CG  1 
ATOM   10867 C CD  . PRO C 3 612 ? 220.158 142.491 53.985  1.00 313.15 ? 635 PRO C CD  1 
ATOM   10868 N N   . ASN C 3 613 ? 222.247 142.237 57.162  1.00 312.95 ? 636 ASN C N   1 
ATOM   10869 C CA  . ASN C 3 613 ? 223.317 142.373 58.138  1.00 312.95 ? 636 ASN C CA  1 
ATOM   10870 C C   . ASN C 3 613 ? 222.996 143.327 59.279  1.00 312.95 ? 636 ASN C C   1 
ATOM   10871 O O   . ASN C 3 613 ? 223.777 143.396 60.236  1.00 312.95 ? 636 ASN C O   1 
ATOM   10872 C CB  . ASN C 3 613 ? 224.611 142.838 57.452  1.00 312.95 ? 636 ASN C CB  1 
ATOM   10873 C CG  . ASN C 3 613 ? 224.420 144.109 56.648  1.00 312.95 ? 636 ASN C CG  1 
ATOM   10874 O OD1 . ASN C 3 613 ? 223.430 144.262 55.932  1.00 312.95 ? 636 ASN C OD1 1 
ATOM   10875 N ND2 . ASN C 3 613 ? 225.370 145.030 56.763  1.00 312.95 ? 636 ASN C ND2 1 
ATOM   10876 N N   . SER C 3 614 ? 221.884 144.056 59.215  1.00 308.62 ? 637 SER C N   1 
ATOM   10877 C CA  . SER C 3 614 ? 221.522 144.998 60.264  1.00 308.62 ? 637 SER C CA  1 
ATOM   10878 C C   . SER C 3 614 ? 220.061 145.383 60.094  1.00 308.62 ? 637 SER C C   1 
ATOM   10879 O O   . SER C 3 614 ? 219.464 145.174 59.035  1.00 308.62 ? 637 SER C O   1 
ATOM   10880 C CB  . SER C 3 614 ? 222.411 146.246 60.234  1.00 308.62 ? 637 SER C CB  1 
ATOM   10881 O OG  . SER C 3 614 ? 221.889 147.223 59.351  1.00 308.62 ? 637 SER C OG  1 
ATOM   10882 N N   . PHE C 3 615 ? 219.492 145.951 61.155  1.00 297.95 ? 638 PHE C N   1 
ATOM   10883 C CA  . PHE C 3 615 ? 218.119 146.432 61.127  1.00 297.95 ? 638 PHE C CA  1 
ATOM   10884 C C   . PHE C 3 615 ? 218.007 147.686 61.980  1.00 297.95 ? 638 PHE C C   1 
ATOM   10885 O O   . PHE C 3 615 ? 218.665 147.815 63.016  1.00 297.95 ? 638 PHE C O   1 
ATOM   10886 C CB  . PHE C 3 615 ? 217.128 145.361 61.612  1.00 297.95 ? 638 PHE C CB  1 
ATOM   10887 C CG  . PHE C 3 615 ? 217.295 144.979 63.055  1.00 297.95 ? 638 PHE C CG  1 
ATOM   10888 C CD1 . PHE C 3 615 ? 218.246 144.047 63.433  1.00 297.95 ? 638 PHE C CD1 1 
ATOM   10889 C CD2 . PHE C 3 615 ? 216.492 145.541 64.034  1.00 297.95 ? 638 PHE C CD2 1 
ATOM   10890 C CE1 . PHE C 3 615 ? 218.399 143.688 64.759  1.00 297.95 ? 638 PHE C CE1 1 
ATOM   10891 C CE2 . PHE C 3 615 ? 216.641 145.187 65.362  1.00 297.95 ? 638 PHE C CE2 1 
ATOM   10892 C CZ  . PHE C 3 615 ? 217.596 144.260 65.724  1.00 297.95 ? 638 PHE C CZ  1 
ATOM   10893 N N   . VAL C 3 616 ? 217.165 148.611 61.529  1.00 292.95 ? 639 VAL C N   1 
ATOM   10894 C CA  . VAL C 3 616 ? 216.963 149.897 62.185  1.00 292.95 ? 639 VAL C CA  1 
ATOM   10895 C C   . VAL C 3 616 ? 215.697 149.821 63.027  1.00 292.95 ? 639 VAL C C   1 
ATOM   10896 O O   . VAL C 3 616 ? 214.726 149.153 62.649  1.00 292.95 ? 639 VAL C O   1 
ATOM   10897 C CB  . VAL C 3 616 ? 216.879 151.032 61.144  1.00 292.95 ? 639 VAL C CB  1 
ATOM   10898 C CG1 . VAL C 3 616 ? 216.625 152.375 61.813  1.00 292.95 ? 639 VAL C CG1 1 
ATOM   10899 C CG2 . VAL C 3 616 ? 218.150 151.078 60.308  1.00 292.95 ? 639 VAL C CG2 1 
ATOM   10900 N N   . LEU C 3 617 ? 215.707 150.495 64.176  1.00 290.23 ? 640 LEU C N   1 
ATOM   10901 C CA  . LEU C 3 617 ? 214.564 150.528 65.076  1.00 290.23 ? 640 LEU C CA  1 
ATOM   10902 C C   . LEU C 3 617 ? 214.181 151.971 65.365  1.00 290.23 ? 640 LEU C C   1 
ATOM   10903 O O   . LEU C 3 617 ? 215.047 152.846 65.456  1.00 290.23 ? 640 LEU C O   1 
ATOM   10904 C CB  . LEU C 3 617 ? 214.865 149.795 66.387  1.00 290.23 ? 640 LEU C CB  1 
ATOM   10905 C CG  . LEU C 3 617 ? 215.126 148.293 66.277  1.00 290.23 ? 640 LEU C CG  1 
ATOM   10906 C CD1 . LEU C 3 617 ? 215.434 147.703 67.644  1.00 290.23 ? 640 LEU C CD1 1 
ATOM   10907 C CD2 . LEU C 3 617 ? 213.937 147.591 65.640  1.00 290.23 ? 640 LEU C CD2 1 
ATOM   10908 N N   . ARG C 3 618 ? 212.880 152.212 65.510  1.00 292.12 ? 641 ARG C N   1 
ATOM   10909 C CA  . ARG C 3 618 ? 212.377 153.548 65.794  1.00 292.12 ? 641 ARG C CA  1 
ATOM   10910 C C   . ARG C 3 618 ? 211.030 153.432 66.491  1.00 292.12 ? 641 ARG C C   1 
ATOM   10911 O O   . ARG C 3 618 ? 210.306 152.448 66.314  1.00 292.12 ? 641 ARG C O   1 
ATOM   10912 C CB  . ARG C 3 618 ? 212.247 154.385 64.515  1.00 292.12 ? 641 ARG C CB  1 
ATOM   10913 C CG  . ARG C 3 618 ? 211.281 153.810 63.491  1.00 292.12 ? 641 ARG C CG  1 
ATOM   10914 C CD  . ARG C 3 618 ? 211.128 154.733 62.293  1.00 292.12 ? 641 ARG C CD  1 
ATOM   10915 N NE  . ARG C 3 618 ? 210.219 154.183 61.291  1.00 292.12 ? 641 ARG C NE  1 
ATOM   10916 C CZ  . ARG C 3 618 ? 208.902 154.360 61.298  1.00 292.12 ? 641 ARG C CZ  1 
ATOM   10917 N NH1 . ARG C 3 618 ? 208.333 155.076 62.258  1.00 292.12 ? 641 ARG C NH1 1 
ATOM   10918 N NH2 . ARG C 3 618 ? 208.154 153.822 60.345  1.00 292.12 ? 641 ARG C NH2 1 
ATOM   10919 N N   . TRP C 3 619 ? 210.706 154.448 67.287  1.00 288.38 ? 642 TRP C N   1 
ATOM   10920 C CA  . TRP C 3 619 ? 209.443 154.512 68.006  1.00 288.38 ? 642 TRP C CA  1 
ATOM   10921 C C   . TRP C 3 619 ? 209.005 155.964 68.081  1.00 288.38 ? 642 TRP C C   1 
ATOM   10922 O O   . TRP C 3 619 ? 209.855 156.863 68.102  1.00 288.38 ? 642 TRP C O   1 
ATOM   10923 C CB  . TRP C 3 619 ? 209.563 153.917 69.418  1.00 288.38 ? 642 TRP C CB  1 
ATOM   10924 C CG  . TRP C 3 619 ? 210.746 154.412 70.190  1.00 288.38 ? 642 TRP C CG  1 
ATOM   10925 C CD1 . TRP C 3 619 ? 210.839 155.580 70.888  1.00 288.38 ? 642 TRP C CD1 1 
ATOM   10926 C CD2 . TRP C 3 619 ? 212.006 153.749 70.347  1.00 288.38 ? 642 TRP C CD2 1 
ATOM   10927 N NE1 . TRP C 3 619 ? 212.080 155.686 71.469  1.00 288.38 ? 642 TRP C NE1 1 
ATOM   10928 C CE2 . TRP C 3 619 ? 212.815 154.575 71.151  1.00 288.38 ? 642 TRP C CE2 1 
ATOM   10929 C CE3 . TRP C 3 619 ? 212.529 152.537 69.884  1.00 288.38 ? 642 TRP C CE3 1 
ATOM   10930 C CZ2 . TRP C 3 619 ? 214.118 154.230 71.502  1.00 288.38 ? 642 TRP C CZ2 1 
ATOM   10931 C CZ3 . TRP C 3 619 ? 213.822 152.196 70.234  1.00 288.38 ? 642 TRP C CZ3 1 
ATOM   10932 C CH2 . TRP C 3 619 ? 214.602 153.039 71.035  1.00 288.38 ? 642 TRP C CH2 1 
ATOM   10933 N N   . PRO C 3 620 ? 207.701 156.230 68.116  1.00 285.86 ? 643 PRO C N   1 
ATOM   10934 C CA  . PRO C 3 620 ? 207.229 157.618 68.185  1.00 285.86 ? 643 PRO C CA  1 
ATOM   10935 C C   . PRO C 3 620 ? 207.606 158.269 69.508  1.00 285.86 ? 643 PRO C C   1 
ATOM   10936 O O   . PRO C 3 620 ? 208.060 157.625 70.455  1.00 285.86 ? 643 PRO C O   1 
ATOM   10937 C CB  . PRO C 3 620 ? 205.710 157.489 68.038  1.00 285.86 ? 643 PRO C CB  1 
ATOM   10938 C CG  . PRO C 3 620 ? 205.405 156.091 68.465  1.00 285.86 ? 643 PRO C CG  1 
ATOM   10939 C CD  . PRO C 3 620 ? 206.586 155.271 68.037  1.00 285.86 ? 643 PRO C CD  1 
ATOM   10940 N N   . ASP C 3 621 ? 207.407 159.584 69.557  1.00 283.24 ? 644 ASP C N   1 
ATOM   10941 C CA  . ASP C 3 621 ? 207.771 160.353 70.738  1.00 283.24 ? 644 ASP C CA  1 
ATOM   10942 C C   . ASP C 3 621 ? 206.866 160.002 71.912  1.00 283.24 ? 644 ASP C C   1 
ATOM   10943 O O   . ASP C 3 621 ? 205.653 159.831 71.757  1.00 283.24 ? 644 ASP C O   1 
ATOM   10944 C CB  . ASP C 3 621 ? 207.693 161.850 70.442  1.00 283.24 ? 644 ASP C CB  1 
ATOM   10945 C CG  . ASP C 3 621 ? 209.045 162.448 70.106  1.00 283.24 ? 644 ASP C CG  1 
ATOM   10946 O OD1 . ASP C 3 621 ? 209.139 163.689 70.002  1.00 283.24 ? 644 ASP C OD1 1 
ATOM   10947 O OD2 . ASP C 3 621 ? 210.015 161.676 69.947  1.00 283.24 ? 644 ASP C OD2 1 
ATOM   10948 N N   . TYR C 3 622 ? 207.467 159.895 73.093  1.00 276.74 ? 645 TYR C N   1 
ATOM   10949 C CA  . TYR C 3 622 ? 206.734 159.562 74.302  1.00 276.74 ? 645 TYR C CA  1 
ATOM   10950 C C   . TYR C 3 622 ? 206.086 160.807 74.901  1.00 276.74 ? 645 TYR C C   1 
ATOM   10951 O O   . TYR C 3 622 ? 206.403 161.943 74.540  1.00 276.74 ? 645 TYR C O   1 
ATOM   10952 C CB  . TYR C 3 622 ? 207.661 158.910 75.329  1.00 276.74 ? 645 TYR C CB  1 
ATOM   10953 C CG  . TYR C 3 622 ? 208.662 159.865 75.942  1.00 276.74 ? 645 TYR C CG  1 
ATOM   10954 C CD1 . TYR C 3 622 ? 208.507 160.323 77.244  1.00 276.74 ? 645 TYR C CD1 1 
ATOM   10955 C CD2 . TYR C 3 622 ? 209.762 160.307 75.219  1.00 276.74 ? 645 TYR C CD2 1 
ATOM   10956 C CE1 . TYR C 3 622 ? 209.419 161.196 77.807  1.00 276.74 ? 645 TYR C CE1 1 
ATOM   10957 C CE2 . TYR C 3 622 ? 210.678 161.180 75.773  1.00 276.74 ? 645 TYR C CE2 1 
ATOM   10958 C CZ  . TYR C 3 622 ? 210.502 161.620 77.068  1.00 276.74 ? 645 TYR C CZ  1 
ATOM   10959 O OH  . TYR C 3 622 ? 211.413 162.489 77.624  1.00 276.74 ? 645 TYR C OH  1 
ATOM   10960 N N   . ASP C 3 623 ? 205.165 160.575 75.834  1.00 274.23 ? 646 ASP C N   1 
ATOM   10961 C CA  . ASP C 3 623 ? 204.469 161.654 76.531  1.00 274.23 ? 646 ASP C CA  1 
ATOM   10962 C C   . ASP C 3 623 ? 205.253 162.002 77.791  1.00 274.23 ? 646 ASP C C   1 
ATOM   10963 O O   . ASP C 3 623 ? 205.209 161.279 78.790  1.00 274.23 ? 646 ASP C O   1 
ATOM   10964 C CB  . ASP C 3 623 ? 203.031 161.252 76.846  1.00 274.23 ? 646 ASP C CB  1 
ATOM   10965 C CG  . ASP C 3 623 ? 202.931 159.873 77.473  1.00 274.23 ? 646 ASP C CG  1 
ATOM   10966 O OD1 . ASP C 3 623 ? 203.959 159.168 77.539  1.00 274.23 ? 646 ASP C OD1 1 
ATOM   10967 O OD2 . ASP C 3 623 ? 201.820 159.495 77.901  1.00 274.23 ? 646 ASP C OD2 1 
ATOM   10968 N N   . SER C 3 624 ? 205.979 163.118 77.745  1.00 276.24 ? 647 SER C N   1 
ATOM   10969 C CA  . SER C 3 624 ? 206.764 163.576 78.883  1.00 276.24 ? 647 SER C CA  1 
ATOM   10970 C C   . SER C 3 624 ? 205.928 164.299 79.930  1.00 276.24 ? 647 SER C C   1 
ATOM   10971 O O   . SER C 3 624 ? 206.491 164.805 80.907  1.00 276.24 ? 647 SER C O   1 
ATOM   10972 C CB  . SER C 3 624 ? 207.896 164.491 78.406  1.00 276.24 ? 647 SER C CB  1 
ATOM   10973 O OG  . SER C 3 624 ? 208.907 164.607 79.391  1.00 276.24 ? 647 SER C OG  1 
ATOM   10974 N N   . ASP C 3 625 ? 204.607 164.363 79.752  1.00 276.17 ? 648 ASP C N   1 
ATOM   10975 C CA  . ASP C 3 625 ? 203.728 165.047 80.689  1.00 276.17 ? 648 ASP C CA  1 
ATOM   10976 C C   . ASP C 3 625 ? 202.786 164.117 81.438  1.00 276.17 ? 648 ASP C C   1 
ATOM   10977 O O   . ASP C 3 625 ? 202.280 164.504 82.496  1.00 276.17 ? 648 ASP C O   1 
ATOM   10978 C CB  . ASP C 3 625 ? 202.895 166.110 79.956  1.00 276.17 ? 648 ASP C CB  1 
ATOM   10979 C CG  . ASP C 3 625 ? 203.755 167.158 79.276  1.00 276.17 ? 648 ASP C CG  1 
ATOM   10980 O OD1 . ASP C 3 625 ? 204.879 167.412 79.759  1.00 276.17 ? 648 ASP C OD1 1 
ATOM   10981 O OD2 . ASP C 3 625 ? 203.307 167.728 78.260  1.00 276.17 ? 648 ASP C OD2 1 
ATOM   10982 N N   . PHE C 3 626 ? 202.540 162.914 80.926  1.00 276.92 ? 649 PHE C N   1 
ATOM   10983 C CA  . PHE C 3 626 ? 201.644 161.947 81.547  1.00 276.92 ? 649 PHE C CA  1 
ATOM   10984 C C   . PHE C 3 626 ? 202.402 160.695 81.972  1.00 276.92 ? 649 PHE C C   1 
ATOM   10985 O O   . PHE C 3 626 ? 201.937 159.569 81.784  1.00 276.92 ? 649 PHE C O   1 
ATOM   10986 C CB  . PHE C 3 626 ? 200.496 161.586 80.606  1.00 276.92 ? 649 PHE C CB  1 
ATOM   10987 C CG  . PHE C 3 626 ? 199.820 162.777 79.989  1.00 276.92 ? 649 PHE C CG  1 
ATOM   10988 C CD1 . PHE C 3 626 ? 198.877 163.500 80.699  1.00 276.92 ? 649 PHE C CD1 1 
ATOM   10989 C CD2 . PHE C 3 626 ? 200.125 163.170 78.696  1.00 276.92 ? 649 PHE C CD2 1 
ATOM   10990 C CE1 . PHE C 3 626 ? 198.253 164.596 80.134  1.00 276.92 ? 649 PHE C CE1 1 
ATOM   10991 C CE2 . PHE C 3 626 ? 199.504 164.265 78.125  1.00 276.92 ? 649 PHE C CE2 1 
ATOM   10992 C CZ  . PHE C 3 626 ? 198.567 164.979 78.845  1.00 276.92 ? 649 PHE C CZ  1 
ATOM   10993 N N   . GLN C 3 627 ? 203.584 160.881 82.551  1.00 275.28 ? 650 GLN C N   1 
ATOM   10994 C CA  . GLN C 3 627 ? 204.431 159.784 82.992  1.00 275.28 ? 650 GLN C CA  1 
ATOM   10995 C C   . GLN C 3 627 ? 204.652 159.870 84.497  1.00 275.28 ? 650 GLN C C   1 
ATOM   10996 O O   . GLN C 3 627 ? 204.281 160.847 85.153  1.00 275.28 ? 650 GLN C O   1 
ATOM   10997 C CB  . GLN C 3 627 ? 205.774 159.796 82.253  1.00 275.28 ? 650 GLN C CB  1 
ATOM   10998 C CG  . GLN C 3 627 ? 206.532 161.107 82.371  1.00 275.28 ? 650 GLN C CG  1 
ATOM   10999 C CD  . GLN C 3 627 ? 207.636 161.233 81.342  1.00 275.28 ? 650 GLN C CD  1 
ATOM   11000 O OE1 . GLN C 3 627 ? 207.644 160.526 80.335  1.00 275.28 ? 650 GLN C OE1 1 
ATOM   11001 N NE2 . GLN C 3 627 ? 208.577 162.138 81.590  1.00 275.28 ? 650 GLN C NE2 1 
ATOM   11002 N N   . ALA C 3 628 ? 205.269 158.824 85.042  1.00 271.25 ? 651 ALA C N   1 
ATOM   11003 C CA  . ALA C 3 628 ? 205.551 158.738 86.468  1.00 271.25 ? 651 ALA C CA  1 
ATOM   11004 C C   . ALA C 3 628 ? 206.918 159.296 86.842  1.00 271.25 ? 651 ALA C C   1 
ATOM   11005 O O   . ALA C 3 628 ? 207.269 159.291 88.026  1.00 271.25 ? 651 ALA C O   1 
ATOM   11006 C CB  . ALA C 3 628 ? 205.445 157.284 86.940  1.00 271.25 ? 651 ALA C CB  1 
ATOM   11007 N N   . GLY C 3 629 ? 207.689 159.772 85.874  1.00 271.93 ? 652 GLY C N   1 
ATOM   11008 C CA  . GLY C 3 629 ? 209.002 160.313 86.166  1.00 271.93 ? 652 GLY C CA  1 
ATOM   11009 C C   . GLY C 3 629 ? 209.691 160.738 84.888  1.00 271.93 ? 652 GLY C C   1 
ATOM   11010 O O   . GLY C 3 629 ? 209.352 160.284 83.790  1.00 271.93 ? 652 GLY C O   1 
ATOM   11011 N N   . PHE C 3 630 ? 210.672 161.623 85.055  1.00 272.07 ? 653 PHE C N   1 
ATOM   11012 C CA  . PHE C 3 630 ? 211.422 162.145 83.920  1.00 272.07 ? 653 PHE C CA  1 
ATOM   11013 C C   . PHE C 3 630 ? 212.243 161.030 83.283  1.00 272.07 ? 653 PHE C C   1 
ATOM   11014 O O   . PHE C 3 630 ? 213.064 160.393 83.951  1.00 272.07 ? 653 PHE C O   1 
ATOM   11015 C CB  . PHE C 3 630 ? 212.325 163.292 84.365  1.00 272.07 ? 653 PHE C CB  1 
ATOM   11016 C CG  . PHE C 3 630 ? 211.575 164.503 84.843  1.00 272.07 ? 653 PHE C CG  1 
ATOM   11017 C CD1 . PHE C 3 630 ? 210.946 165.346 83.941  1.00 272.07 ? 653 PHE C CD1 1 
ATOM   11018 C CD2 . PHE C 3 630 ? 211.501 164.800 86.193  1.00 272.07 ? 653 PHE C CD2 1 
ATOM   11019 C CE1 . PHE C 3 630 ? 210.256 166.461 84.377  1.00 272.07 ? 653 PHE C CE1 1 
ATOM   11020 C CE2 . PHE C 3 630 ? 210.813 165.914 86.636  1.00 272.07 ? 653 PHE C CE2 1 
ATOM   11021 C CZ  . PHE C 3 630 ? 210.189 166.745 85.727  1.00 272.07 ? 653 PHE C CZ  1 
ATOM   11022 N N   . ILE C 3 631 ? 212.022 160.797 81.994  1.00 273.41 ? 654 ILE C N   1 
ATOM   11023 C CA  . ILE C 3 631 ? 212.725 159.742 81.273  1.00 273.41 ? 654 ILE C CA  1 
ATOM   11024 C C   . ILE C 3 631 ? 214.124 160.226 80.919  1.00 273.41 ? 654 ILE C C   1 
ATOM   11025 O O   . ILE C 3 631 ? 214.293 161.289 80.309  1.00 273.41 ? 654 ILE C O   1 
ATOM   11026 C CB  . ILE C 3 631 ? 211.945 159.329 80.015  1.00 273.41 ? 654 ILE C CB  1 
ATOM   11027 C CG1 . ILE C 3 631 ? 210.507 158.953 80.378  1.00 273.41 ? 654 ILE C CG1 1 
ATOM   11028 C CG2 . ILE C 3 631 ? 212.639 158.175 79.313  1.00 273.41 ? 654 ILE C CG2 1 
ATOM   11029 C CD1 . ILE C 3 631 ? 210.399 157.725 81.254  1.00 273.41 ? 654 ILE C CD1 1 
ATOM   11030 N N   . LYS C 3 632 ? 215.134 159.446 81.303  1.00 272.85 ? 655 LYS C N   1 
ATOM   11031 C CA  . LYS C 3 632 ? 216.519 159.782 81.003  1.00 272.85 ? 655 LYS C CA  1 
ATOM   11032 C C   . LYS C 3 632 ? 217.026 159.132 79.724  1.00 272.85 ? 655 LYS C C   1 
ATOM   11033 O O   . LYS C 3 632 ? 218.026 159.596 79.164  1.00 272.85 ? 655 LYS C O   1 
ATOM   11034 C CB  . LYS C 3 632 ? 217.427 159.379 82.169  1.00 272.85 ? 655 LYS C CB  1 
ATOM   11035 C CG  . LYS C 3 632 ? 217.739 160.509 83.139  1.00 272.85 ? 655 LYS C CG  1 
ATOM   11036 C CD  . LYS C 3 632 ? 216.537 160.843 84.008  1.00 272.85 ? 655 LYS C CD  1 
ATOM   11037 C CE  . LYS C 3 632 ? 216.967 161.384 85.362  1.00 272.85 ? 655 LYS C CE  1 
ATOM   11038 N NZ  . LYS C 3 632 ? 215.856 162.088 86.059  1.00 272.85 ? 655 LYS C NZ  1 
ATOM   11039 N N   . GLY C 3 633 ? 216.367 158.076 79.252  1.00 278.82 ? 656 GLY C N   1 
ATOM   11040 C CA  . GLY C 3 633 ? 216.785 157.401 78.039  1.00 278.82 ? 656 GLY C CA  1 
ATOM   11041 C C   . GLY C 3 633 ? 215.977 156.152 77.751  1.00 278.82 ? 656 GLY C C   1 
ATOM   11042 O O   . GLY C 3 633 ? 214.797 156.072 78.105  1.00 278.82 ? 656 GLY C O   1 
ATOM   11043 N N   . TYR C 3 634 ? 216.602 155.168 77.109  1.00 283.28 ? 657 TYR C N   1 
ATOM   11044 C CA  . TYR C 3 634 ? 215.940 153.916 76.776  1.00 283.28 ? 657 TYR C CA  1 
ATOM   11045 C C   . TYR C 3 634 ? 216.914 152.763 76.961  1.00 283.28 ? 657 TYR C C   1 
ATOM   11046 O O   . TYR C 3 634 ? 218.106 152.895 76.672  1.00 283.28 ? 657 TYR C O   1 
ATOM   11047 C CB  . TYR C 3 634 ? 215.411 153.924 75.335  1.00 283.28 ? 657 TYR C CB  1 
ATOM   11048 C CG  . TYR C 3 634 ? 214.294 154.912 75.091  1.00 283.28 ? 657 TYR C CG  1 
ATOM   11049 C CD1 . TYR C 3 634 ? 212.970 154.564 75.321  1.00 283.28 ? 657 TYR C CD1 1 
ATOM   11050 C CD2 . TYR C 3 634 ? 214.563 156.193 74.625  1.00 283.28 ? 657 TYR C CD2 1 
ATOM   11051 C CE1 . TYR C 3 634 ? 211.945 155.464 75.097  1.00 283.28 ? 657 TYR C CE1 1 
ATOM   11052 C CE2 . TYR C 3 634 ? 213.545 157.099 74.398  1.00 283.28 ? 657 TYR C CE2 1 
ATOM   11053 C CZ  . TYR C 3 634 ? 212.239 156.730 74.636  1.00 283.28 ? 657 TYR C CZ  1 
ATOM   11054 O OH  . TYR C 3 634 ? 211.222 157.628 74.411  1.00 283.28 ? 657 TYR C OH  1 
ATOM   11055 N N   . LEU C 3 635 ? 216.400 151.635 77.447  1.00 283.81 ? 658 LEU C N   1 
ATOM   11056 C CA  . LEU C 3 635 ? 217.183 150.416 77.621  1.00 283.81 ? 658 LEU C CA  1 
ATOM   11057 C C   . LEU C 3 635 ? 216.587 149.336 76.728  1.00 283.81 ? 658 LEU C C   1 
ATOM   11058 O O   . LEU C 3 635 ? 215.464 148.879 76.963  1.00 283.81 ? 658 LEU C O   1 
ATOM   11059 C CB  . LEU C 3 635 ? 217.200 149.968 79.082  1.00 283.81 ? 658 LEU C CB  1 
ATOM   11060 C CG  . LEU C 3 635 ? 217.345 151.039 80.164  1.00 283.81 ? 658 LEU C CG  1 
ATOM   11061 C CD1 . LEU C 3 635 ? 217.399 150.390 81.537  1.00 283.81 ? 658 LEU C CD1 1 
ATOM   11062 C CD2 . LEU C 3 635 ? 218.586 151.883 79.924  1.00 283.81 ? 658 LEU C CD2 1 
ATOM   11063 N N   . VAL C 3 636 ? 217.337 148.932 75.707  1.00 282.47 ? 659 VAL C N   1 
ATOM   11064 C CA  . VAL C 3 636 ? 216.916 147.875 74.798  1.00 282.47 ? 659 VAL C CA  1 
ATOM   11065 C C   . VAL C 3 636 ? 217.656 146.597 75.165  1.00 282.47 ? 659 VAL C C   1 
ATOM   11066 O O   . VAL C 3 636 ? 218.768 146.628 75.706  1.00 282.47 ? 659 VAL C O   1 
ATOM   11067 C CB  . VAL C 3 636 ? 217.159 148.249 73.320  1.00 282.47 ? 659 VAL C CB  1 
ATOM   11068 C CG1 . VAL C 3 636 ? 216.483 149.570 72.990  1.00 282.47 ? 659 VAL C CG1 1 
ATOM   11069 C CG2 . VAL C 3 636 ? 218.648 148.318 73.021  1.00 282.47 ? 659 VAL C CG2 1 
ATOM   11070 N N   . TYR C 3 637 ? 217.021 145.463 74.879  1.00 279.20 ? 660 TYR C N   1 
ATOM   11071 C CA  . TYR C 3 637 ? 217.599 144.152 75.162  1.00 279.20 ? 660 TYR C CA  1 
ATOM   11072 C C   . TYR C 3 637 ? 217.351 143.258 73.956  1.00 279.20 ? 660 TYR C C   1 
ATOM   11073 O O   . TYR C 3 637 ? 216.215 142.837 73.716  1.00 279.20 ? 660 TYR C O   1 
ATOM   11074 C CB  . TYR C 3 637 ? 216.999 143.539 76.427  1.00 279.20 ? 660 TYR C CB  1 
ATOM   11075 C CG  . TYR C 3 637 ? 217.307 144.309 77.691  1.00 279.20 ? 660 TYR C CG  1 
ATOM   11076 C CD1 . TYR C 3 637 ? 218.442 144.028 78.439  1.00 279.20 ? 660 TYR C CD1 1 
ATOM   11077 C CD2 . TYR C 3 637 ? 216.460 145.315 78.139  1.00 279.20 ? 660 TYR C CD2 1 
ATOM   11078 C CE1 . TYR C 3 637 ? 218.727 144.728 79.596  1.00 279.20 ? 660 TYR C CE1 1 
ATOM   11079 C CE2 . TYR C 3 637 ? 216.736 146.020 79.294  1.00 279.20 ? 660 TYR C CE2 1 
ATOM   11080 C CZ  . TYR C 3 637 ? 217.871 145.723 80.019  1.00 279.20 ? 660 TYR C CZ  1 
ATOM   11081 O OH  . TYR C 3 637 ? 218.150 146.423 81.170  1.00 279.20 ? 660 TYR C OH  1 
ATOM   11082 N N   . VAL C 3 638 ? 218.403 142.971 73.206  1.00 275.62 ? 661 VAL C N   1 
ATOM   11083 C CA  . VAL C 3 638 ? 218.309 142.119 72.028  1.00 275.62 ? 661 VAL C CA  1 
ATOM   11084 C C   . VAL C 3 638 ? 218.617 140.683 72.427  1.00 275.62 ? 661 VAL C C   1 
ATOM   11085 O O   . VAL C 3 638 ? 219.379 140.421 73.365  1.00 275.62 ? 661 VAL C O   1 
ATOM   11086 C CB  . VAL C 3 638 ? 219.250 142.615 70.909  1.00 275.62 ? 661 VAL C CB  1 
ATOM   11087 C CG1 . VAL C 3 638 ? 218.981 144.080 70.606  1.00 275.62 ? 661 VAL C CG1 1 
ATOM   11088 C CG2 . VAL C 3 638 ? 220.703 142.413 71.305  1.00 275.62 ? 661 VAL C CG2 1 
ATOM   11089 N N   . LYS C 3 639 ? 218.006 139.740 71.714  1.00 275.05 ? 662 LYS C N   1 
ATOM   11090 C CA  . LYS C 3 639 ? 218.195 138.320 71.975  1.00 275.05 ? 662 LYS C CA  1 
ATOM   11091 C C   . LYS C 3 639 ? 218.449 137.607 70.657  1.00 275.05 ? 662 LYS C C   1 
ATOM   11092 O O   . LYS C 3 639 ? 217.705 137.802 69.692  1.00 275.05 ? 662 LYS C O   1 
ATOM   11093 C CB  . LYS C 3 639 ? 216.974 137.718 72.682  1.00 275.05 ? 662 LYS C CB  1 
ATOM   11094 C CG  . LYS C 3 639 ? 217.128 136.253 73.058  1.00 275.05 ? 662 LYS C CG  1 
ATOM   11095 C CD  . LYS C 3 639 ? 215.894 135.742 73.783  1.00 275.05 ? 662 LYS C CD  1 
ATOM   11096 C CE  . LYS C 3 639 ? 216.058 134.291 74.202  1.00 275.05 ? 662 LYS C CE  1 
ATOM   11097 N NZ  . LYS C 3 639 ? 214.865 133.792 74.939  1.00 275.05 ? 662 LYS C NZ  1 
ATOM   11098 N N   . SER C 3 640 ? 219.495 136.786 70.620  1.00 272.29 ? 663 SER C N   1 
ATOM   11099 C CA  . SER C 3 640 ? 219.869 136.066 69.412  1.00 272.29 ? 663 SER C CA  1 
ATOM   11100 C C   . SER C 3 640 ? 220.485 134.731 69.807  1.00 272.29 ? 663 SER C C   1 
ATOM   11101 O O   . SER C 3 640 ? 220.591 134.397 70.991  1.00 272.29 ? 663 SER C O   1 
ATOM   11102 C CB  . SER C 3 640 ? 220.829 136.896 68.554  1.00 272.29 ? 663 SER C CB  1 
ATOM   11103 O OG  . SER C 3 640 ? 221.821 137.511 69.357  1.00 272.29 ? 663 SER C OG  1 
ATOM   11104 N N   . LYS C 3 641 ? 220.894 133.960 68.796  1.00 269.57 ? 664 LYS C N   1 
ATOM   11105 C CA  . LYS C 3 641 ? 221.494 132.651 69.010  1.00 269.57 ? 664 LYS C CA  1 
ATOM   11106 C C   . LYS C 3 641 ? 222.989 132.614 68.735  1.00 269.57 ? 664 LYS C C   1 
ATOM   11107 O O   . LYS C 3 641 ? 223.675 131.736 69.269  1.00 269.57 ? 664 LYS C O   1 
ATOM   11108 C CB  . LYS C 3 641 ? 220.813 131.589 68.128  1.00 269.57 ? 664 LYS C CB  1 
ATOM   11109 C CG  . LYS C 3 641 ? 219.294 131.704 67.975  1.00 269.57 ? 664 LYS C CG  1 
ATOM   11110 C CD  . LYS C 3 641 ? 218.579 131.971 69.293  1.00 269.57 ? 664 LYS C CD  1 
ATOM   11111 C CE  . LYS C 3 641 ? 217.193 132.552 69.058  1.00 269.57 ? 664 LYS C CE  1 
ATOM   11112 N NZ  . LYS C 3 641 ? 217.242 133.804 68.254  1.00 269.57 ? 664 LYS C NZ  1 
ATOM   11113 N N   . GLU C 3 642 ? 223.508 133.535 67.923  1.00 275.92 ? 665 GLU C N   1 
ATOM   11114 C CA  . GLU C 3 642 ? 224.923 133.538 67.561  1.00 275.92 ? 665 GLU C CA  1 
ATOM   11115 C C   . GLU C 3 642 ? 225.594 134.898 67.668  1.00 275.92 ? 665 GLU C C   1 
ATOM   11116 O O   . GLU C 3 642 ? 226.825 134.943 67.766  1.00 275.92 ? 665 GLU C O   1 
ATOM   11117 C CB  . GLU C 3 642 ? 225.103 133.002 66.133  1.00 275.92 ? 665 GLU C CB  1 
ATOM   11118 C CG  . GLU C 3 642 ? 226.411 132.259 65.886  1.00 275.92 ? 665 GLU C CG  1 
ATOM   11119 C CD  . GLU C 3 642 ? 227.531 133.170 65.419  1.00 275.92 ? 665 GLU C CD  1 
ATOM   11120 O OE1 . GLU C 3 642 ? 227.247 134.334 65.064  1.00 275.92 ? 665 GLU C OE1 1 
ATOM   11121 O OE2 . GLU C 3 642 ? 228.696 132.721 65.406  1.00 275.92 ? 665 GLU C OE2 1 
ATOM   11122 N N   . MET C 3 643 ? 224.849 136.002 67.667  1.00 284.98 ? 666 MET C N   1 
ATOM   11123 C CA  . MET C 3 643 ? 225.449 137.327 67.708  1.00 284.98 ? 666 MET C CA  1 
ATOM   11124 C C   . MET C 3 643 ? 226.207 137.541 69.016  1.00 284.98 ? 666 MET C C   1 
ATOM   11125 O O   . MET C 3 643 ? 225.849 137.013 70.072  1.00 284.98 ? 666 MET C O   1 
ATOM   11126 C CB  . MET C 3 643 ? 224.372 138.400 67.543  1.00 284.98 ? 666 MET C CB  1 
ATOM   11127 C CG  . MET C 3 643 ? 224.905 139.813 67.367  1.00 284.98 ? 666 MET C CG  1 
ATOM   11128 S SD  . MET C 3 643 ? 223.681 141.073 67.768  1.00 284.98 ? 666 MET C SD  1 
ATOM   11129 C CE  . MET C 3 643 ? 223.140 140.511 69.379  1.00 284.98 ? 666 MET C CE  1 
ATOM   11130 N N   . GLN C 3 644 ? 227.277 138.329 68.931  1.00 293.73 ? 667 GLN C N   1 
ATOM   11131 C CA  . GLN C 3 644 ? 228.097 138.679 70.079  1.00 293.73 ? 667 GLN C CA  1 
ATOM   11132 C C   . GLN C 3 644 ? 227.863 140.137 70.450  1.00 293.73 ? 667 GLN C C   1 
ATOM   11133 O O   . GLN C 3 644 ? 227.491 140.958 69.606  1.00 293.73 ? 667 GLN C O   1 
ATOM   11134 C CB  . GLN C 3 644 ? 229.585 138.444 69.793  1.00 293.73 ? 667 GLN C CB  1 
ATOM   11135 C CG  . GLN C 3 644 ? 229.956 136.981 69.607  1.00 293.73 ? 667 GLN C CG  1 
ATOM   11136 C CD  . GLN C 3 644 ? 231.305 136.803 68.940  1.00 293.73 ? 667 GLN C CD  1 
ATOM   11137 O OE1 . GLN C 3 644 ? 232.337 136.735 69.607  1.00 293.73 ? 667 GLN C OE1 1 
ATOM   11138 N NE2 . GLN C 3 644 ? 231.303 136.725 67.614  1.00 293.73 ? 667 GLN C NE2 1 
ATOM   11139 N N   . CYS C 3 645 ? 228.084 140.453 71.725  1.00 293.97 ? 668 CYS C N   1 
ATOM   11140 C CA  . CYS C 3 645 ? 227.860 141.802 72.244  1.00 293.97 ? 668 CYS C CA  1 
ATOM   11141 C C   . CYS C 3 645 ? 229.133 142.615 72.045  1.00 293.97 ? 668 CYS C C   1 
ATOM   11142 O O   . CYS C 3 645 ? 230.067 142.557 72.845  1.00 293.97 ? 668 CYS C O   1 
ATOM   11143 C CB  . CYS C 3 645 ? 227.446 141.755 73.709  1.00 293.97 ? 668 CYS C CB  1 
ATOM   11144 S SG  . CYS C 3 645 ? 226.044 140.668 74.059  1.00 293.97 ? 668 CYS C SG  1 
ATOM   11145 N N   . ASN C 3 646 ? 229.169 143.383 70.960  1.00 300.92 ? 669 ASN C N   1 
ATOM   11146 C CA  . ASN C 3 646 ? 230.294 144.266 70.695  1.00 300.92 ? 669 ASN C CA  1 
ATOM   11147 C C   . ASN C 3 646 ? 230.160 145.540 71.522  1.00 300.92 ? 669 ASN C C   1 
ATOM   11148 O O   . ASN C 3 646 ? 229.054 145.993 71.826  1.00 300.92 ? 669 ASN C O   1 
ATOM   11149 C CB  . ASN C 3 646 ? 230.371 144.604 69.203  1.00 300.92 ? 669 ASN C CB  1 
ATOM   11150 C CG  . ASN C 3 646 ? 231.639 145.359 68.832  1.00 300.92 ? 669 ASN C CG  1 
ATOM   11151 O OD1 . ASN C 3 646 ? 231.957 146.398 69.411  1.00 300.92 ? 669 ASN C OD1 1 
ATOM   11152 N ND2 . ASN C 3 646 ? 232.369 144.835 67.854  1.00 300.92 ? 669 ASN C ND2 1 
ATOM   11153 N N   . GLN C 3 647 ? 231.305 146.112 71.887  1.00 303.17 ? 670 GLN C N   1 
ATOM   11154 C CA  . GLN C 3 647 ? 231.314 147.317 72.701  1.00 303.17 ? 670 GLN C CA  1 
ATOM   11155 C C   . GLN C 3 647 ? 230.577 148.450 71.985  1.00 303.17 ? 670 GLN C C   1 
ATOM   11156 O O   . GLN C 3 647 ? 230.614 148.545 70.754  1.00 303.17 ? 670 GLN C O   1 
ATOM   11157 C CB  . GLN C 3 647 ? 232.750 147.737 73.012  1.00 303.17 ? 670 GLN C CB  1 
ATOM   11158 C CG  . GLN C 3 647 ? 233.248 147.281 74.374  1.00 303.17 ? 670 GLN C CG  1 
ATOM   11159 C CD  . GLN C 3 647 ? 233.086 145.789 74.585  1.00 303.17 ? 670 GLN C CD  1 
ATOM   11160 O OE1 . GLN C 3 647 ? 233.776 144.983 73.959  1.00 303.17 ? 670 GLN C OE1 1 
ATOM   11161 N NE2 . GLN C 3 647 ? 232.172 145.412 75.471  1.00 303.17 ? 670 GLN C NE2 1 
ATOM   11162 N N   . PRO C 3 648 ? 229.895 149.332 72.734  1.00 298.93 ? 671 PRO C N   1 
ATOM   11163 C CA  . PRO C 3 648 ? 229.798 149.320 74.196  1.00 298.93 ? 671 PRO C CA  1 
ATOM   11164 C C   . PRO C 3 648 ? 228.546 148.625 74.731  1.00 298.93 ? 671 PRO C C   1 
ATOM   11165 O O   . PRO C 3 648 ? 227.880 149.171 75.611  1.00 298.93 ? 671 PRO C O   1 
ATOM   11166 C CB  . PRO C 3 648 ? 229.768 150.807 74.539  1.00 298.93 ? 671 PRO C CB  1 
ATOM   11167 C CG  . PRO C 3 648 ? 229.018 151.414 73.389  1.00 298.93 ? 671 PRO C CG  1 
ATOM   11168 C CD  . PRO C 3 648 ? 229.290 150.551 72.167  1.00 298.93 ? 671 PRO C CD  1 
ATOM   11169 N N   . TRP C 3 649 ? 228.231 147.442 74.211  1.00 288.62 ? 672 TRP C N   1 
ATOM   11170 C CA  . TRP C 3 649 ? 227.081 146.678 74.676  1.00 288.62 ? 672 TRP C CA  1 
ATOM   11171 C C   . TRP C 3 649 ? 227.515 145.713 75.772  1.00 288.62 ? 672 TRP C C   1 
ATOM   11172 O O   . TRP C 3 649 ? 228.470 144.949 75.594  1.00 288.62 ? 672 TRP C O   1 
ATOM   11173 C CB  . TRP C 3 649 ? 226.430 145.911 73.524  1.00 288.62 ? 672 TRP C CB  1 
ATOM   11174 C CG  . TRP C 3 649 ? 225.782 146.787 72.490  1.00 288.62 ? 672 TRP C CG  1 
ATOM   11175 C CD1 . TRP C 3 649 ? 226.387 147.748 71.732  1.00 288.62 ? 672 TRP C CD1 1 
ATOM   11176 C CD2 . TRP C 3 649 ? 224.405 146.773 72.093  1.00 288.62 ? 672 TRP C CD2 1 
ATOM   11177 N NE1 . TRP C 3 649 ? 225.472 148.337 70.893  1.00 288.62 ? 672 TRP C NE1 1 
ATOM   11178 C CE2 . TRP C 3 649 ? 224.247 147.756 71.095  1.00 288.62 ? 672 TRP C CE2 1 
ATOM   11179 C CE3 . TRP C 3 649 ? 223.289 146.028 72.487  1.00 288.62 ? 672 TRP C CE3 1 
ATOM   11180 C CZ2 . TRP C 3 649 ? 223.021 148.012 70.485  1.00 288.62 ? 672 TRP C CZ2 1 
ATOM   11181 C CZ3 . TRP C 3 649 ? 222.072 146.283 71.880  1.00 288.62 ? 672 TRP C CZ3 1 
ATOM   11182 C CH2 . TRP C 3 649 ? 221.948 147.267 70.891  1.00 288.62 ? 672 TRP C CH2 1 
ATOM   11183 N N   . GLU C 3 650 ? 226.812 145.750 76.902  1.00 274.45 ? 673 GLU C N   1 
ATOM   11184 C CA  . GLU C 3 650 ? 227.114 144.864 78.017  1.00 274.45 ? 673 GLU C CA  1 
ATOM   11185 C C   . GLU C 3 650 ? 226.590 143.463 77.728  1.00 274.45 ? 673 GLU C C   1 
ATOM   11186 O O   . GLU C 3 650 ? 225.431 143.293 77.337  1.00 274.45 ? 673 GLU C O   1 
ATOM   11187 C CB  . GLU C 3 650 ? 226.498 145.403 79.308  1.00 274.45 ? 673 GLU C CB  1 
ATOM   11188 C CG  . GLU C 3 650 ? 226.363 144.365 80.411  1.00 274.45 ? 673 GLU C CG  1 
ATOM   11189 C CD  . GLU C 3 650 ? 225.498 144.844 81.559  1.00 274.45 ? 673 GLU C CD  1 
ATOM   11190 O OE1 . GLU C 3 650 ? 225.461 146.068 81.806  1.00 274.45 ? 673 GLU C OE1 1 
ATOM   11191 O OE2 . GLU C 3 650 ? 224.856 143.997 82.215  1.00 274.45 ? 673 GLU C OE2 1 
ATOM   11192 N N   . ARG C 3 651 ? 227.444 142.462 77.921  1.00 262.05 ? 674 ARG C N   1 
ATOM   11193 C CA  . ARG C 3 651 ? 227.083 141.070 77.687  1.00 262.05 ? 674 ARG C CA  1 
ATOM   11194 C C   . ARG C 3 651 ? 226.640 140.426 78.994  1.00 262.05 ? 674 ARG C C   1 
ATOM   11195 O O   . ARG C 3 651 ? 227.301 140.582 80.026  1.00 262.05 ? 674 ARG C O   1 
ATOM   11196 C CB  . ARG C 3 651 ? 228.255 140.292 77.086  1.00 262.05 ? 674 ARG C CB  1 
ATOM   11197 C CG  . ARG C 3 651 ? 227.920 138.849 76.739  1.00 262.05 ? 674 ARG C CG  1 
ATOM   11198 C CD  . ARG C 3 651 ? 229.092 138.144 76.078  1.00 262.05 ? 674 ARG C CD  1 
ATOM   11199 N NE  . ARG C 3 651 ? 228.763 136.769 75.714  1.00 262.05 ? 674 ARG C NE  1 
ATOM   11200 C CZ  . ARG C 3 651 ? 229.601 135.936 75.106  1.00 262.05 ? 674 ARG C CZ  1 
ATOM   11201 N NH1 . ARG C 3 651 ? 230.825 136.335 74.791  1.00 262.05 ? 674 ARG C NH1 1 
ATOM   11202 N NH2 . ARG C 3 651 ? 229.215 134.702 74.813  1.00 262.05 ? 674 ARG C NH2 1 
ATOM   11203 N N   . THR C 3 652 ? 225.521 139.706 78.944  1.00 254.44 ? 675 THR C N   1 
ATOM   11204 C CA  . THR C 3 652 ? 224.996 138.987 80.097  1.00 254.44 ? 675 THR C CA  1 
ATOM   11205 C C   . THR C 3 652 ? 224.505 137.624 79.638  1.00 254.44 ? 675 THR C C   1 
ATOM   11206 O O   . THR C 3 652 ? 223.672 137.536 78.731  1.00 254.44 ? 675 THR C O   1 
ATOM   11207 C CB  . THR C 3 652 ? 223.858 139.764 80.772  1.00 254.44 ? 675 THR C CB  1 
ATOM   11208 O OG1 . THR C 3 652 ? 224.374 140.973 81.342  1.00 254.44 ? 675 THR C OG1 1 
ATOM   11209 C CG2 . THR C 3 652 ? 223.217 138.925 81.868  1.00 254.44 ? 675 THR C CG2 1 
ATOM   11210 N N   . LEU C 3 653 ? 225.019 136.570 80.262  1.00 242.54 ? 676 LEU C N   1 
ATOM   11211 C CA  . LEU C 3 653 ? 224.686 135.214 79.856  1.00 242.54 ? 676 LEU C CA  1 
ATOM   11212 C C   . LEU C 3 653 ? 223.338 134.789 80.427  1.00 242.54 ? 676 LEU C C   1 
ATOM   11213 O O   . LEU C 3 653 ? 222.921 135.235 81.500  1.00 242.54 ? 676 LEU C O   1 
ATOM   11214 C CB  . LEU C 3 653 ? 225.773 134.236 80.305  1.00 242.54 ? 676 LEU C CB  1 
ATOM   11215 C CG  . LEU C 3 653 ? 227.190 134.468 79.775  1.00 242.54 ? 676 LEU C CG  1 
ATOM   11216 C CD1 . LEU C 3 653 ? 228.002 133.185 79.849  1.00 242.54 ? 676 LEU C CD1 1 
ATOM   11217 C CD2 . LEU C 3 653 ? 227.165 135.001 78.348  1.00 242.54 ? 676 LEU C CD2 1 
ATOM   11218 N N   . LEU C 3 654 ? 222.655 133.916 79.688  1.00 248.01 ? 677 LEU C N   1 
ATOM   11219 C CA  . LEU C 3 654 ? 221.373 133.364 80.084  1.00 248.01 ? 677 LEU C CA  1 
ATOM   11220 C C   . LEU C 3 654 ? 221.471 131.848 80.209  1.00 248.01 ? 677 LEU C C   1 
ATOM   11221 O O   . LEU C 3 654 ? 222.142 131.204 79.395  1.00 248.01 ? 677 LEU C O   1 
ATOM   11222 C CB  . LEU C 3 654 ? 220.280 133.727 79.065  1.00 248.01 ? 677 LEU C CB  1 
ATOM   11223 C CG  . LEU C 3 654 ? 218.830 133.734 79.554  1.00 248.01 ? 677 LEU C CG  1 
ATOM   11224 C CD1 . LEU C 3 654 ? 218.616 134.819 80.597  1.00 248.01 ? 677 LEU C CD1 1 
ATOM   11225 C CD2 . LEU C 3 654 ? 217.869 133.912 78.389  1.00 248.01 ? 677 LEU C CD2 1 
ATOM   11226 N N   . PRO C 3 655 ? 220.825 131.250 81.216  1.00 255.10 ? 678 PRO C N   1 
ATOM   11227 C CA  . PRO C 3 655 ? 220.897 129.787 81.374  1.00 255.10 ? 678 PRO C CA  1 
ATOM   11228 C C   . PRO C 3 655 ? 220.301 129.005 80.213  1.00 255.10 ? 678 PRO C C   1 
ATOM   11229 O O   . PRO C 3 655 ? 220.482 127.781 80.163  1.00 255.10 ? 678 PRO C O   1 
ATOM   11230 C CB  . PRO C 3 655 ? 220.114 129.534 82.670  1.00 255.10 ? 678 PRO C CB  1 
ATOM   11231 C CG  . PRO C 3 655 ? 220.167 130.832 83.406  1.00 255.10 ? 678 PRO C CG  1 
ATOM   11232 C CD  . PRO C 3 655 ? 220.142 131.896 82.350  1.00 255.10 ? 678 PRO C CD  1 
ATOM   11233 N N   . ASP C 3 656 ? 219.602 129.658 79.284  1.00 257.76 ? 679 ASP C N   1 
ATOM   11234 C CA  . ASP C 3 656 ? 219.013 128.990 78.132  1.00 257.76 ? 679 ASP C CA  1 
ATOM   11235 C C   . ASP C 3 656 ? 219.981 128.878 76.958  1.00 257.76 ? 679 ASP C C   1 
ATOM   11236 O O   . ASP C 3 656 ? 219.536 128.708 75.817  1.00 257.76 ? 679 ASP C O   1 
ATOM   11237 C CB  . ASP C 3 656 ? 217.741 129.720 77.695  1.00 257.76 ? 679 ASP C CB  1 
ATOM   11238 C CG  . ASP C 3 656 ? 216.557 129.414 78.591  1.00 257.76 ? 679 ASP C CG  1 
ATOM   11239 O OD1 . ASP C 3 656 ? 216.753 128.757 79.635  1.00 257.76 ? 679 ASP C OD1 1 
ATOM   11240 O OD2 . ASP C 3 656 ? 215.429 129.832 78.251  1.00 257.76 ? 679 ASP C OD2 1 
ATOM   11241 N N   . ASN C 3 657 ? 221.288 128.974 77.216  1.00 258.07 ? 680 ASN C N   1 
ATOM   11242 C CA  . ASN C 3 657 ? 222.318 128.864 76.180  1.00 258.07 ? 680 ASN C CA  1 
ATOM   11243 C C   . ASN C 3 657 ? 222.123 129.913 75.087  1.00 258.07 ? 680 ASN C C   1 
ATOM   11244 O O   . ASN C 3 657 ? 222.166 129.609 73.893  1.00 258.07 ? 680 ASN C O   1 
ATOM   11245 C CB  . ASN C 3 657 ? 222.357 127.455 75.582  1.00 258.07 ? 680 ASN C CB  1 
ATOM   11246 C CG  . ASN C 3 657 ? 222.809 126.409 76.582  1.00 258.07 ? 680 ASN C CG  1 
ATOM   11247 O OD1 . ASN C 3 657 ? 223.952 125.953 76.547  1.00 258.07 ? 680 ASN C OD1 1 
ATOM   11248 N ND2 . ASN C 3 657 ? 221.911 126.021 77.480  1.00 258.07 ? 680 ASN C ND2 1 
ATOM   11249 N N   . SER C 3 658 ? 221.907 131.157 75.498  1.00 253.03 ? 681 SER C N   1 
ATOM   11250 C CA  . SER C 3 658 ? 221.683 132.268 74.584  1.00 253.03 ? 681 SER C CA  1 
ATOM   11251 C C   . SER C 3 658 ? 222.629 133.417 74.924  1.00 253.03 ? 681 SER C C   1 
ATOM   11252 O O   . SER C 3 658 ? 223.534 133.288 75.752  1.00 253.03 ? 681 SER C O   1 
ATOM   11253 C CB  . SER C 3 658 ? 220.224 132.727 74.633  1.00 253.03 ? 681 SER C CB  1 
ATOM   11254 O OG  . SER C 3 658 ? 219.911 133.297 75.891  1.00 253.03 ? 681 SER C OG  1 
ATOM   11255 N N   . VAL C 3 659 ? 222.406 134.552 74.265  1.00 264.16 ? 682 VAL C N   1 
ATOM   11256 C CA  . VAL C 3 659 ? 223.213 135.751 74.446  1.00 264.16 ? 682 VAL C CA  1 
ATOM   11257 C C   . VAL C 3 659 ? 222.278 136.937 74.645  1.00 264.16 ? 682 VAL C C   1 
ATOM   11258 O O   . VAL C 3 659 ? 221.227 137.027 74.000  1.00 264.16 ? 682 VAL C O   1 
ATOM   11259 C CB  . VAL C 3 659 ? 224.161 135.980 73.247  1.00 264.16 ? 682 VAL C CB  1 
ATOM   11260 C CG1 . VAL C 3 659 ? 223.378 136.017 71.941  1.00 264.16 ? 682 VAL C CG1 1 
ATOM   11261 C CG2 . VAL C 3 659 ? 224.977 137.252 73.431  1.00 264.16 ? 682 VAL C CG2 1 
ATOM   11262 N N   . LEU C 3 660 ? 222.653 137.841 75.550  1.00 264.21 ? 683 LEU C N   1 
ATOM   11263 C CA  . LEU C 3 660 ? 221.853 139.018 75.866  1.00 264.21 ? 683 LEU C CA  1 
ATOM   11264 C C   . LEU C 3 660 ? 222.766 140.232 75.926  1.00 264.21 ? 683 LEU C C   1 
ATOM   11265 O O   . LEU C 3 660 ? 223.648 140.305 76.787  1.00 264.21 ? 683 LEU C O   1 
ATOM   11266 C CB  . LEU C 3 660 ? 221.107 138.839 77.191  1.00 264.21 ? 683 LEU C CB  1 
ATOM   11267 C CG  . LEU C 3 660 ? 220.225 140.002 77.647  1.00 264.21 ? 683 LEU C CG  1 
ATOM   11268 C CD1 . LEU C 3 660 ? 219.090 140.233 76.663  1.00 264.21 ? 683 LEU C CD1 1 
ATOM   11269 C CD2 . LEU C 3 660 ? 219.682 139.748 79.044  1.00 264.21 ? 683 LEU C CD2 1 
ATOM   11270 N N   . CYS C 3 661 ? 222.555 141.178 75.015  1.00 278.29 ? 684 CYS C N   1 
ATOM   11271 C CA  . CYS C 3 661 ? 223.326 142.411 74.957  1.00 278.29 ? 684 CYS C CA  1 
ATOM   11272 C C   . CYS C 3 661 ? 222.471 143.578 75.433  1.00 278.29 ? 684 CYS C C   1 
ATOM   11273 O O   . CYS C 3 661 ? 221.292 143.680 75.080  1.00 278.29 ? 684 CYS C O   1 
ATOM   11274 C CB  . CYS C 3 661 ? 223.834 142.678 73.537  1.00 278.29 ? 684 CYS C CB  1 
ATOM   11275 S SG  . CYS C 3 661 ? 224.615 141.256 72.741  1.00 278.29 ? 684 CYS C SG  1 
ATOM   11276 N N   . LYS C 3 662 ? 223.069 144.455 76.234  1.00 281.97 ? 685 LYS C N   1 
ATOM   11277 C CA  . LYS C 3 662 ? 222.378 145.598 76.812  1.00 281.97 ? 685 LYS C CA  1 
ATOM   11278 C C   . LYS C 3 662 ? 222.935 146.893 76.235  1.00 281.97 ? 685 LYS C C   1 
ATOM   11279 O O   . LYS C 3 662 ? 224.151 147.046 76.085  1.00 281.97 ? 685 LYS C O   1 
ATOM   11280 C CB  . LYS C 3 662 ? 222.514 145.605 78.337  1.00 281.97 ? 685 LYS C CB  1 
ATOM   11281 C CG  . LYS C 3 662 ? 221.788 146.751 79.023  1.00 281.97 ? 685 LYS C CG  1 
ATOM   11282 C CD  . LYS C 3 662 ? 221.917 146.662 80.534  1.00 281.97 ? 685 LYS C CD  1 
ATOM   11283 C CE  . LYS C 3 662 ? 221.161 147.788 81.217  1.00 281.97 ? 685 LYS C CE  1 
ATOM   11284 N NZ  . LYS C 3 662 ? 221.225 147.679 82.700  1.00 281.97 ? 685 LYS C NZ  1 
ATOM   11285 N N   . TYR C 3 663 ? 222.037 147.824 75.915  1.00 286.05 ? 686 TYR C N   1 
ATOM   11286 C CA  . TYR C 3 663 ? 222.407 149.126 75.372  1.00 286.05 ? 686 TYR C CA  1 
ATOM   11287 C C   . TYR C 3 663 ? 221.659 150.198 76.149  1.00 286.05 ? 686 TYR C C   1 
ATOM   11288 O O   . TYR C 3 663 ? 220.423 150.215 76.156  1.00 286.05 ? 686 TYR C O   1 
ATOM   11289 C CB  . TYR C 3 663 ? 222.081 149.210 73.876  1.00 286.05 ? 686 TYR C CB  1 
ATOM   11290 C CG  . TYR C 3 663 ? 222.348 150.556 73.228  1.00 286.05 ? 686 TYR C CG  1 
ATOM   11291 C CD1 . TYR C 3 663 ? 223.286 151.439 73.751  1.00 286.05 ? 686 TYR C CD1 1 
ATOM   11292 C CD2 . TYR C 3 663 ? 221.652 150.943 72.091  1.00 286.05 ? 686 TYR C CD2 1 
ATOM   11293 C CE1 . TYR C 3 663 ? 223.523 152.666 73.159  1.00 286.05 ? 686 TYR C CE1 1 
ATOM   11294 C CE2 . TYR C 3 663 ? 221.883 152.167 71.491  1.00 286.05 ? 686 TYR C CE2 1 
ATOM   11295 C CZ  . TYR C 3 663 ? 222.818 153.024 72.029  1.00 286.05 ? 686 TYR C CZ  1 
ATOM   11296 O OH  . TYR C 3 663 ? 223.050 154.243 71.435  1.00 286.05 ? 686 TYR C OH  1 
ATOM   11297 N N   . ASP C 3 664 ? 222.405 151.088 76.798  1.00 285.22 ? 687 ASP C N   1 
ATOM   11298 C CA  . ASP C 3 664 ? 221.828 152.221 77.518  1.00 285.22 ? 687 ASP C CA  1 
ATOM   11299 C C   . ASP C 3 664 ? 221.856 153.424 76.583  1.00 285.22 ? 687 ASP C C   1 
ATOM   11300 O O   . ASP C 3 664 ? 222.909 154.023 76.352  1.00 285.22 ? 687 ASP C O   1 
ATOM   11301 C CB  . ASP C 3 664 ? 222.596 152.490 78.808  1.00 285.22 ? 687 ASP C CB  1 
ATOM   11302 C CG  . ASP C 3 664 ? 221.955 153.571 79.663  1.00 285.22 ? 687 ASP C CG  1 
ATOM   11303 O OD1 . ASP C 3 664 ? 220.914 154.130 79.256  1.00 285.22 ? 687 ASP C OD1 1 
ATOM   11304 O OD2 . ASP C 3 664 ? 222.497 153.863 80.750  1.00 285.22 ? 687 ASP C OD2 1 
ATOM   11305 N N   . ILE C 3 665 ? 220.693 153.781 76.041  1.00 284.28 ? 688 ILE C N   1 
ATOM   11306 C CA  . ILE C 3 665 ? 220.576 154.913 75.123  1.00 284.28 ? 688 ILE C CA  1 
ATOM   11307 C C   . ILE C 3 665 ? 220.654 156.185 75.961  1.00 284.28 ? 688 ILE C C   1 
ATOM   11308 O O   . ILE C 3 665 ? 219.676 156.590 76.591  1.00 284.28 ? 688 ILE C O   1 
ATOM   11309 C CB  . ILE C 3 665 ? 219.288 154.853 74.300  1.00 284.28 ? 688 ILE C CB  1 
ATOM   11310 C CG1 . ILE C 3 665 ? 219.250 153.572 73.463  1.00 284.28 ? 688 ILE C CG1 1 
ATOM   11311 C CG2 . ILE C 3 665 ? 219.171 156.077 73.403  1.00 284.28 ? 688 ILE C CG2 1 
ATOM   11312 C CD1 . ILE C 3 665 ? 217.941 153.352 72.737  1.00 284.28 ? 688 ILE C CD1 1 
ATOM   11313 N N   . ASN C 3 666 ? 221.825 156.819 75.972  1.00 279.78 ? 689 ASN C N   1 
ATOM   11314 C CA  . ASN C 3 666 ? 222.035 158.042 76.739  1.00 279.78 ? 689 ASN C CA  1 
ATOM   11315 C C   . ASN C 3 666 ? 221.348 159.199 76.023  1.00 279.78 ? 689 ASN C C   1 
ATOM   11316 O O   . ASN C 3 666 ? 221.762 159.597 74.930  1.00 279.78 ? 689 ASN C O   1 
ATOM   11317 C CB  . ASN C 3 666 ? 223.527 158.310 76.916  1.00 279.78 ? 689 ASN C CB  1 
ATOM   11318 C CG  . ASN C 3 666 ? 224.297 157.069 77.322  1.00 279.78 ? 689 ASN C CG  1 
ATOM   11319 O OD1 . ASN C 3 666 ? 224.072 156.508 78.395  1.00 279.78 ? 689 ASN C OD1 1 
ATOM   11320 N ND2 . ASN C 3 666 ? 225.211 156.633 76.464  1.00 279.78 ? 689 ASN C ND2 1 
ATOM   11321 N N   . GLY C 3 667 ? 220.298 159.737 76.637  1.00 276.36 ? 690 GLY C N   1 
ATOM   11322 C CA  . GLY C 3 667 ? 219.554 160.829 76.043  1.00 276.36 ? 690 GLY C CA  1 
ATOM   11323 C C   . GLY C 3 667 ? 218.148 160.434 75.644  1.00 276.36 ? 690 GLY C C   1 
ATOM   11324 O O   . GLY C 3 667 ? 217.952 159.449 74.926  1.00 276.36 ? 690 GLY C O   1 
ATOM   11325 N N   . SER C 3 668 ? 217.160 161.196 76.105  1.00 275.45 ? 691 SER C N   1 
ATOM   11326 C CA  . SER C 3 668 ? 215.760 160.928 75.806  1.00 275.45 ? 691 SER C CA  1 
ATOM   11327 C C   . SER C 3 668 ? 215.294 161.598 74.519  1.00 275.45 ? 691 SER C C   1 
ATOM   11328 O O   . SER C 3 668 ? 214.087 161.638 74.258  1.00 275.45 ? 691 SER C O   1 
ATOM   11329 C CB  . SER C 3 668 ? 214.879 161.376 76.975  1.00 275.45 ? 691 SER C CB  1 
ATOM   11330 O OG  . SER C 3 668 ? 213.580 160.822 76.876  1.00 275.45 ? 691 SER C OG  1 
ATOM   11331 N N   . GLU C 3 669 ? 216.218 162.121 73.714  1.00 277.30 ? 692 GLU C N   1 
ATOM   11332 C CA  . GLU C 3 669 ? 215.870 162.785 72.464  1.00 277.30 ? 692 GLU C CA  1 
ATOM   11333 C C   . GLU C 3 669 ? 215.898 161.821 71.282  1.00 277.30 ? 692 GLU C C   1 
ATOM   11334 O O   . GLU C 3 669 ? 214.895 161.669 70.577  1.00 277.30 ? 692 GLU C O   1 
ATOM   11335 C CB  . GLU C 3 669 ? 216.821 163.960 72.214  1.00 277.30 ? 692 GLU C CB  1 
ATOM   11336 C CG  . GLU C 3 669 ? 216.492 164.796 70.983  1.00 277.30 ? 692 GLU C CG  1 
ATOM   11337 C CD  . GLU C 3 669 ? 215.002 164.996 70.785  1.00 277.30 ? 692 GLU C CD  1 
ATOM   11338 O OE1 . GLU C 3 669 ? 214.423 164.333 69.898  1.00 277.30 ? 692 GLU C OE1 1 
ATOM   11339 O OE2 . GLU C 3 669 ? 214.409 165.816 71.516  1.00 277.30 ? 692 GLU C OE2 1 
ATOM   11340 N N   . THR C 3 670 ? 217.033 161.164 71.056  1.00 280.92 ? 693 THR C N   1 
ATOM   11341 C CA  . THR C 3 670 ? 217.156 160.250 69.929  1.00 280.92 ? 693 THR C CA  1 
ATOM   11342 C C   . THR C 3 670 ? 216.251 159.036 70.114  1.00 280.92 ? 693 THR C C   1 
ATOM   11343 O O   . THR C 3 670 ? 216.160 158.462 71.203  1.00 280.92 ? 693 THR C O   1 
ATOM   11344 C CB  . THR C 3 670 ? 218.612 159.811 69.753  1.00 280.92 ? 693 THR C CB  1 
ATOM   11345 O OG1 . THR C 3 670 ? 218.708 158.878 68.669  1.00 280.92 ? 693 THR C OG1 1 
ATOM   11346 C CG2 . THR C 3 670 ? 219.157 159.176 71.029  1.00 280.92 ? 693 THR C CG2 1 
ATOM   11347 N N   . LYS C 3 671 ? 215.560 158.660 69.037  1.00 286.89 ? 694 LYS C N   1 
ATOM   11348 C CA  . LYS C 3 671 ? 214.651 157.520 69.046  1.00 286.89 ? 694 LYS C CA  1 
ATOM   11349 C C   . LYS C 3 671 ? 215.007 156.488 67.985  1.00 286.89 ? 694 LYS C C   1 
ATOM   11350 O O   . LYS C 3 671 ? 214.195 155.597 67.705  1.00 286.89 ? 694 LYS C O   1 
ATOM   11351 C CB  . LYS C 3 671 ? 213.205 157.988 68.851  1.00 286.89 ? 694 LYS C CB  1 
ATOM   11352 C CG  . LYS C 3 671 ? 212.804 159.182 69.707  1.00 286.89 ? 694 LYS C CG  1 
ATOM   11353 C CD  . LYS C 3 671 ? 212.919 158.872 71.190  1.00 286.89 ? 694 LYS C CD  1 
ATOM   11354 C CE  . LYS C 3 671 ? 212.223 159.930 72.031  1.00 286.89 ? 694 LYS C CE  1 
ATOM   11355 N NZ  . LYS C 3 671 ? 212.739 161.297 71.741  1.00 286.89 ? 694 LYS C NZ  1 
ATOM   11356 N N   . THR C 3 672 ? 216.193 156.580 67.388  1.00 289.14 ? 695 THR C N   1 
ATOM   11357 C CA  . THR C 3 672 ? 216.608 155.686 66.315  1.00 289.14 ? 695 THR C CA  1 
ATOM   11358 C C   . THR C 3 672 ? 217.963 155.087 66.655  1.00 289.14 ? 695 THR C C   1 
ATOM   11359 O O   . THR C 3 672 ? 218.888 155.811 67.037  1.00 289.14 ? 695 THR C O   1 
ATOM   11360 C CB  . THR C 3 672 ? 216.679 156.426 64.974  1.00 289.14 ? 695 THR C CB  1 
ATOM   11361 O OG1 . THR C 3 672 ? 215.529 157.269 64.829  1.00 289.14 ? 695 THR C OG1 1 
ATOM   11362 C CG2 . THR C 3 672 ? 216.722 155.436 63.821  1.00 289.14 ? 695 THR C CG2 1 
ATOM   11363 N N   . LEU C 3 673 ? 218.076 153.768 66.516  1.00 290.31 ? 696 LEU C N   1 
ATOM   11364 C CA  . LEU C 3 673 ? 219.312 153.053 66.800  1.00 290.31 ? 696 LEU C CA  1 
ATOM   11365 C C   . LEU C 3 673 ? 219.476 151.917 65.801  1.00 290.31 ? 696 LEU C C   1 
ATOM   11366 O O   . LEU C 3 673 ? 218.495 151.285 65.400  1.00 290.31 ? 696 LEU C O   1 
ATOM   11367 C CB  . LEU C 3 673 ? 219.338 152.503 68.237  1.00 290.31 ? 696 LEU C CB  1 
ATOM   11368 C CG  . LEU C 3 673 ? 218.448 151.314 68.621  1.00 290.31 ? 696 LEU C CG  1 
ATOM   11369 C CD1 . LEU C 3 673 ? 218.833 150.792 69.993  1.00 290.31 ? 696 LEU C CD1 1 
ATOM   11370 C CD2 . LEU C 3 673 ? 216.975 151.687 68.606  1.00 290.31 ? 696 LEU C CD2 1 
ATOM   11371 N N   . THR C 3 674 ? 220.721 151.672 65.395  1.00 298.48 ? 697 THR C N   1 
ATOM   11372 C CA  . THR C 3 674 ? 221.050 150.621 64.438  1.00 298.48 ? 697 THR C CA  1 
ATOM   11373 C C   . THR C 3 674 ? 222.120 149.725 65.041  1.00 298.48 ? 697 THR C C   1 
ATOM   11374 O O   . THR C 3 674 ? 223.188 150.208 65.431  1.00 298.48 ? 697 THR C O   1 
ATOM   11375 C CB  . THR C 3 674 ? 221.536 151.205 63.106  1.00 298.48 ? 697 THR C CB  1 
ATOM   11376 O OG1 . THR C 3 674 ? 222.906 151.609 63.230  1.00 298.48 ? 697 THR C OG1 1 
ATOM   11377 C CG2 . THR C 3 674 ? 220.693 152.406 62.697  1.00 298.48 ? 697 THR C CG2 1 
ATOM   11378 N N   . VAL C 3 675 ? 221.835 148.427 65.117  1.00 303.47 ? 698 VAL C N   1 
ATOM   11379 C CA  . VAL C 3 675 ? 222.774 147.435 65.627  1.00 303.47 ? 698 VAL C CA  1 
ATOM   11380 C C   . VAL C 3 675 ? 223.335 146.647 64.451  1.00 303.47 ? 698 VAL C C   1 
ATOM   11381 O O   . VAL C 3 675 ? 222.618 146.354 63.485  1.00 303.47 ? 698 VAL C O   1 
ATOM   11382 C CB  . VAL C 3 675 ? 222.098 146.510 66.660  1.00 303.47 ? 698 VAL C CB  1 
ATOM   11383 C CG1 . VAL C 3 675 ? 220.873 145.834 66.060  1.00 303.47 ? 698 VAL C CG1 1 
ATOM   11384 C CG2 . VAL C 3 675 ? 223.083 145.480 67.199  1.00 303.47 ? 698 VAL C CG2 1 
ATOM   11385 N N   . GLU C 3 676 ? 224.619 146.312 64.522  1.00 303.19 ? 699 GLU C N   1 
ATOM   11386 C CA  . GLU C 3 676 ? 225.328 145.641 63.440  1.00 303.19 ? 699 GLU C CA  1 
ATOM   11387 C C   . GLU C 3 676 ? 225.800 144.262 63.906  1.00 303.19 ? 699 GLU C C   1 
ATOM   11388 O O   . GLU C 3 676 ? 225.447 143.795 64.994  1.00 303.19 ? 699 GLU C O   1 
ATOM   11389 C CB  . GLU C 3 676 ? 226.481 146.519 62.941  1.00 303.19 ? 699 GLU C CB  1 
ATOM   11390 C CG  . GLU C 3 676 ? 227.522 146.890 63.994  1.00 303.19 ? 699 GLU C CG  1 
ATOM   11391 C CD  . GLU C 3 676 ? 228.544 145.796 64.232  1.00 303.19 ? 699 GLU C CD  1 
ATOM   11392 O OE1 . GLU C 3 676 ? 228.844 145.047 63.279  1.00 303.19 ? 699 GLU C OE1 1 
ATOM   11393 O OE2 . GLU C 3 676 ? 229.045 145.685 65.370  1.00 303.19 ? 699 GLU C OE2 1 
ATOM   11394 N N   . ASN C 3 677 ? 226.601 143.610 63.059  1.00 301.96 ? 700 ASN C N   1 
ATOM   11395 C CA  . ASN C 3 677 ? 227.117 142.261 63.301  1.00 301.96 ? 700 ASN C CA  1 
ATOM   11396 C C   . ASN C 3 677 ? 225.973 141.248 63.407  1.00 301.96 ? 700 ASN C C   1 
ATOM   11397 O O   . ASN C 3 677 ? 225.759 140.604 64.435  1.00 301.96 ? 700 ASN C O   1 
ATOM   11398 C CB  . ASN C 3 677 ? 228.013 142.228 64.547  1.00 301.96 ? 700 ASN C CB  1 
ATOM   11399 C CG  . ASN C 3 677 ? 228.683 140.881 64.751  1.00 301.96 ? 700 ASN C CG  1 
ATOM   11400 O OD1 . ASN C 3 677 ? 229.752 140.617 64.200  1.00 301.96 ? 700 ASN C OD1 1 
ATOM   11401 N ND2 . ASN C 3 677 ? 228.057 140.024 65.548  1.00 301.96 ? 700 ASN C ND2 1 
ATOM   11402 N N   . LEU C 3 678 ? 225.230 141.126 62.310  1.00 304.39 ? 701 LEU C N   1 
ATOM   11403 C CA  . LEU C 3 678 ? 224.143 140.166 62.195  1.00 304.39 ? 701 LEU C CA  1 
ATOM   11404 C C   . LEU C 3 678 ? 224.386 139.252 61.003  1.00 304.39 ? 701 LEU C C   1 
ATOM   11405 O O   . LEU C 3 678 ? 225.036 139.637 60.026  1.00 304.39 ? 701 LEU C O   1 
ATOM   11406 C CB  . LEU C 3 678 ? 222.788 140.869 62.037  1.00 304.39 ? 701 LEU C CB  1 
ATOM   11407 C CG  . LEU C 3 678 ? 222.101 141.383 63.302  1.00 304.39 ? 701 LEU C CG  1 
ATOM   11408 C CD1 . LEU C 3 678 ? 222.632 142.753 63.687  1.00 304.39 ? 701 LEU C CD1 1 
ATOM   11409 C CD2 . LEU C 3 678 ? 220.598 141.431 63.098  1.00 304.39 ? 701 LEU C CD2 1 
ATOM   11410 N N   . GLN C 3 679 ? 223.855 138.028 61.090  1.00 303.18 ? 702 GLN C N   1 
ATOM   11411 C CA  . GLN C 3 679 ? 223.950 137.101 59.975  1.00 303.18 ? 702 GLN C CA  1 
ATOM   11412 C C   . GLN C 3 679 ? 222.576 136.863 59.357  1.00 303.18 ? 702 GLN C C   1 
ATOM   11413 O O   . GLN C 3 679 ? 221.569 136.823 60.074  1.00 303.18 ? 702 GLN C O   1 
ATOM   11414 C CB  . GLN C 3 679 ? 224.565 135.758 60.400  1.00 303.18 ? 702 GLN C CB  1 
ATOM   11415 C CG  . GLN C 3 679 ? 223.701 134.887 61.306  1.00 303.18 ? 702 GLN C CG  1 
ATOM   11416 C CD  . GLN C 3 679 ? 223.580 135.439 62.713  1.00 303.18 ? 702 GLN C CD  1 
ATOM   11417 O OE1 . GLN C 3 679 ? 224.403 136.244 63.149  1.00 303.18 ? 702 GLN C OE1 1 
ATOM   11418 N NE2 . GLN C 3 679 ? 222.552 135.006 63.434  1.00 303.18 ? 702 GLN C NE2 1 
ATOM   11419 N N   . PRO C 3 680 ? 222.500 136.725 58.037  1.00 306.51 ? 703 PRO C N   1 
ATOM   11420 C CA  . PRO C 3 680 ? 221.202 136.588 57.371  1.00 306.51 ? 703 PRO C CA  1 
ATOM   11421 C C   . PRO C 3 680 ? 220.626 135.187 57.544  1.00 306.51 ? 703 PRO C C   1 
ATOM   11422 O O   . PRO C 3 680 ? 221.304 134.248 57.965  1.00 306.51 ? 703 PRO C O   1 
ATOM   11423 C CB  . PRO C 3 680 ? 221.521 136.879 55.897  1.00 306.51 ? 703 PRO C CB  1 
ATOM   11424 C CG  . PRO C 3 680 ? 222.934 137.416 55.880  1.00 306.51 ? 703 PRO C CG  1 
ATOM   11425 C CD  . PRO C 3 680 ? 223.604 136.820 57.071  1.00 306.51 ? 703 PRO C CD  1 
ATOM   11426 N N   . GLU C 3 681 ? 219.345 135.066 57.189  1.00 302.44 ? 704 GLU C N   1 
ATOM   11427 C CA  . GLU C 3 681 ? 218.577 133.830 57.357  1.00 302.44 ? 704 GLU C CA  1 
ATOM   11428 C C   . GLU C 3 681 ? 218.677 133.315 58.792  1.00 302.44 ? 704 GLU C C   1 
ATOM   11429 O O   . GLU C 3 681 ? 218.955 132.140 59.043  1.00 302.44 ? 704 GLU C O   1 
ATOM   11430 C CB  . GLU C 3 681 ? 219.007 132.750 56.356  1.00 302.44 ? 704 GLU C CB  1 
ATOM   11431 C CG  . GLU C 3 681 ? 219.003 133.157 54.879  1.00 302.44 ? 704 GLU C CG  1 
ATOM   11432 C CD  . GLU C 3 681 ? 220.157 134.061 54.492  1.00 302.44 ? 704 GLU C CD  1 
ATOM   11433 O OE1 . GLU C 3 681 ? 221.292 133.803 54.945  1.00 302.44 ? 704 GLU C OE1 1 
ATOM   11434 O OE2 . GLU C 3 681 ? 219.930 135.028 53.735  1.00 302.44 ? 704 GLU C OE2 1 
ATOM   11435 N N   . SER C 3 682 ? 218.443 134.213 59.746  1.00 297.48 ? 705 SER C N   1 
ATOM   11436 C CA  . SER C 3 682 ? 218.557 133.901 61.164  1.00 297.48 ? 705 SER C CA  1 
ATOM   11437 C C   . SER C 3 682 ? 217.278 134.318 61.883  1.00 297.48 ? 705 SER C C   1 
ATOM   11438 O O   . SER C 3 682 ? 216.316 134.791 61.272  1.00 297.48 ? 705 SER C O   1 
ATOM   11439 C CB  . SER C 3 682 ? 219.780 134.589 61.783  1.00 297.48 ? 705 SER C CB  1 
ATOM   11440 O OG  . SER C 3 682 ? 219.653 134.692 63.191  1.00 297.48 ? 705 SER C OG  1 
ATOM   11441 N N   . LEU C 3 683 ? 217.277 134.130 63.201  1.00 287.25 ? 706 LEU C N   1 
ATOM   11442 C CA  . LEU C 3 683 ? 216.164 134.501 64.062  1.00 287.25 ? 706 LEU C CA  1 
ATOM   11443 C C   . LEU C 3 683 ? 216.646 135.502 65.102  1.00 287.25 ? 706 LEU C C   1 
ATOM   11444 O O   . LEU C 3 683 ? 217.751 135.369 65.638  1.00 287.25 ? 706 LEU C O   1 
ATOM   11445 C CB  . LEU C 3 683 ? 215.564 133.270 64.752  1.00 287.25 ? 706 LEU C CB  1 
ATOM   11446 C CG  . LEU C 3 683 ? 214.089 133.347 65.152  1.00 287.25 ? 706 LEU C CG  1 
ATOM   11447 C CD1 . LEU C 3 683 ? 213.204 133.495 63.924  1.00 287.25 ? 706 LEU C CD1 1 
ATOM   11448 C CD2 . LEU C 3 683 ? 213.687 132.125 65.963  1.00 287.25 ? 706 LEU C CD2 1 
ATOM   11449 N N   . TYR C 3 684 ? 215.819 136.507 65.382  1.00 287.97 ? 707 TYR C N   1 
ATOM   11450 C CA  . TYR C 3 684 ? 216.178 137.562 66.317  1.00 287.97 ? 707 TYR C CA  1 
ATOM   11451 C C   . TYR C 3 684 ? 214.959 137.976 67.126  1.00 287.97 ? 707 TYR C C   1 
ATOM   11452 O O   . TYR C 3 684 ? 213.845 138.041 66.598  1.00 287.97 ? 707 TYR C O   1 
ATOM   11453 C CB  . TYR C 3 684 ? 216.757 138.782 65.589  1.00 287.97 ? 707 TYR C CB  1 
ATOM   11454 C CG  . TYR C 3 684 ? 218.096 138.525 64.938  1.00 287.97 ? 707 TYR C CG  1 
ATOM   11455 C CD1 . TYR C 3 684 ? 219.272 138.601 65.671  1.00 287.97 ? 707 TYR C CD1 1 
ATOM   11456 C CD2 . TYR C 3 684 ? 218.184 138.205 63.590  1.00 287.97 ? 707 TYR C CD2 1 
ATOM   11457 C CE1 . TYR C 3 684 ? 220.499 138.367 65.081  1.00 287.97 ? 707 TYR C CE1 1 
ATOM   11458 C CE2 . TYR C 3 684 ? 219.405 137.969 62.990  1.00 287.97 ? 707 TYR C CE2 1 
ATOM   11459 C CZ  . TYR C 3 684 ? 220.559 138.050 63.741  1.00 287.97 ? 707 TYR C CZ  1 
ATOM   11460 O OH  . TYR C 3 684 ? 221.777 137.817 63.147  1.00 287.97 ? 707 TYR C OH  1 
ATOM   11461 N N   . GLU C 3 685 ? 215.180 138.253 68.409  1.00 281.62 ? 708 GLU C N   1 
ATOM   11462 C CA  . GLU C 3 685 ? 214.141 138.729 69.308  1.00 281.62 ? 708 GLU C CA  1 
ATOM   11463 C C   . GLU C 3 685 ? 214.653 139.948 70.063  1.00 281.62 ? 708 GLU C C   1 
ATOM   11464 O O   . GLU C 3 685 ? 215.844 140.052 70.366  1.00 281.62 ? 708 GLU C O   1 
ATOM   11465 C CB  . GLU C 3 685 ? 213.704 137.641 70.304  1.00 281.62 ? 708 GLU C CB  1 
ATOM   11466 C CG  . GLU C 3 685 ? 213.111 136.394 69.664  1.00 281.62 ? 708 GLU C CG  1 
ATOM   11467 C CD  . GLU C 3 685 ? 214.168 135.411 69.198  1.00 281.62 ? 708 GLU C CD  1 
ATOM   11468 O OE1 . GLU C 3 685 ? 214.192 135.086 67.993  1.00 281.62 ? 708 GLU C OE1 1 
ATOM   11469 O OE2 . GLU C 3 685 ? 214.976 134.962 70.039  1.00 281.62 ? 708 GLU C OE2 1 
ATOM   11470 N N   . PHE C 3 686 ? 213.741 140.869 70.364  1.00 281.59 ? 709 PHE C N   1 
ATOM   11471 C CA  . PHE C 3 686 ? 214.108 142.107 71.040  1.00 281.59 ? 709 PHE C CA  1 
ATOM   11472 C C   . PHE C 3 686 ? 212.856 142.738 71.633  1.00 281.59 ? 709 PHE C C   1 
ATOM   11473 O O   . PHE C 3 686 ? 211.728 142.382 71.285  1.00 281.59 ? 709 PHE C O   1 
ATOM   11474 C CB  . PHE C 3 686 ? 214.805 143.081 70.084  1.00 281.59 ? 709 PHE C CB  1 
ATOM   11475 C CG  . PHE C 3 686 ? 213.866 143.777 69.138  1.00 281.59 ? 709 PHE C CG  1 
ATOM   11476 C CD1 . PHE C 3 686 ? 213.382 143.125 68.016  1.00 281.59 ? 709 PHE C CD1 1 
ATOM   11477 C CD2 . PHE C 3 686 ? 213.467 145.084 69.372  1.00 281.59 ? 709 PHE C CD2 1 
ATOM   11478 C CE1 . PHE C 3 686 ? 212.517 143.762 67.146  1.00 281.59 ? 709 PHE C CE1 1 
ATOM   11479 C CE2 . PHE C 3 686 ? 212.601 145.725 68.506  1.00 281.59 ? 709 PHE C CE2 1 
ATOM   11480 C CZ  . PHE C 3 686 ? 212.127 145.063 67.391  1.00 281.59 ? 709 PHE C CZ  1 
ATOM   11481 N N   . PHE C 3 687 ? 213.076 143.691 72.537  1.00 284.51 ? 710 PHE C N   1 
ATOM   11482 C CA  . PHE C 3 687 ? 211.998 144.473 73.122  1.00 284.51 ? 710 PHE C CA  1 
ATOM   11483 C C   . PHE C 3 687 ? 212.586 145.759 73.685  1.00 284.51 ? 710 PHE C C   1 
ATOM   11484 O O   . PHE C 3 687 ? 213.718 145.775 74.175  1.00 284.51 ? 710 PHE C O   1 
ATOM   11485 C CB  . PHE C 3 687 ? 211.252 143.692 74.212  1.00 284.51 ? 710 PHE C CB  1 
ATOM   11486 C CG  . PHE C 3 687 ? 212.046 143.490 75.472  1.00 284.51 ? 710 PHE C CG  1 
ATOM   11487 C CD1 . PHE C 3 687 ? 211.838 144.301 76.576  1.00 284.51 ? 710 PHE C CD1 1 
ATOM   11488 C CD2 . PHE C 3 687 ? 212.992 142.482 75.556  1.00 284.51 ? 710 PHE C CD2 1 
ATOM   11489 C CE1 . PHE C 3 687 ? 212.565 144.115 77.737  1.00 284.51 ? 710 PHE C CE1 1 
ATOM   11490 C CE2 . PHE C 3 687 ? 213.721 142.291 76.714  1.00 284.51 ? 710 PHE C CE2 1 
ATOM   11491 C CZ  . PHE C 3 687 ? 213.507 143.109 77.805  1.00 284.51 ? 710 PHE C CZ  1 
ATOM   11492 N N   . VAL C 3 688 ? 211.805 146.833 73.607  1.00 284.51 ? 711 VAL C N   1 
ATOM   11493 C CA  . VAL C 3 688 ? 212.246 148.154 74.034  1.00 284.51 ? 711 VAL C CA  1 
ATOM   11494 C C   . VAL C 3 688 ? 211.438 148.582 75.251  1.00 284.51 ? 711 VAL C C   1 
ATOM   11495 O O   . VAL C 3 688 ? 210.266 148.217 75.409  1.00 284.51 ? 711 VAL C O   1 
ATOM   11496 C CB  . VAL C 3 688 ? 212.127 149.187 72.889  1.00 284.51 ? 711 VAL C CB  1 
ATOM   11497 C CG1 . VAL C 3 688 ? 210.668 149.506 72.592  1.00 284.51 ? 711 VAL C CG1 1 
ATOM   11498 C CG2 . VAL C 3 688 ? 212.905 150.453 73.220  1.00 284.51 ? 711 VAL C CG2 1 
ATOM   11499 N N   . THR C 3 689 ? 212.085 149.354 76.131  1.00 284.41 ? 712 THR C N   1 
ATOM   11500 C CA  . THR C 3 689 ? 211.439 149.887 77.322  1.00 284.41 ? 712 THR C CA  1 
ATOM   11501 C C   . THR C 3 689 ? 212.243 151.071 77.829  1.00 284.41 ? 712 THR C C   1 
ATOM   11502 O O   . THR C 3 689 ? 213.477 151.058 77.716  1.00 284.41 ? 712 THR C O   1 
ATOM   11503 C CB  . THR C 3 689 ? 211.302 148.817 78.417  1.00 284.41 ? 712 THR C CB  1 
ATOM   11504 O OG1 . THR C 3 689 ? 210.507 149.327 79.496  1.00 284.41 ? 712 THR C OG1 1 
ATOM   11505 C CG2 . THR C 3 689 ? 212.665 148.381 78.946  1.00 284.41 ? 712 THR C CG2 1 
ATOM   11506 N N   . PRO C 3 690 ? 211.599 152.109 78.348  1.00 282.06 ? 713 PRO C N   1 
ATOM   11507 C CA  . PRO C 3 690 ? 212.330 153.248 78.909  1.00 282.06 ? 713 PRO C CA  1 
ATOM   11508 C C   . PRO C 3 690 ? 212.773 152.951 80.338  1.00 282.06 ? 713 PRO C C   1 
ATOM   11509 O O   . PRO C 3 690 ? 212.585 151.855 80.862  1.00 282.06 ? 713 PRO C O   1 
ATOM   11510 C CB  . PRO C 3 690 ? 211.299 154.377 78.860  1.00 282.06 ? 713 PRO C CB  1 
ATOM   11511 C CG  . PRO C 3 690 ? 209.992 153.678 79.009  1.00 282.06 ? 713 PRO C CG  1 
ATOM   11512 C CD  . PRO C 3 690 ? 210.143 152.338 78.331  1.00 282.06 ? 713 PRO C CD  1 
ATOM   11513 N N   . TYR C 3 691 ? 213.374 153.959 80.968  1.00 274.29 ? 714 TYR C N   1 
ATOM   11514 C CA  . TYR C 3 691 ? 213.838 153.827 82.341  1.00 274.29 ? 714 TYR C CA  1 
ATOM   11515 C C   . TYR C 3 691 ? 213.860 155.196 83.002  1.00 274.29 ? 714 TYR C C   1 
ATOM   11516 O O   . TYR C 3 691 ? 214.086 156.217 82.346  1.00 274.29 ? 714 TYR C O   1 
ATOM   11517 C CB  . TYR C 3 691 ? 215.227 153.180 82.407  1.00 274.29 ? 714 TYR C CB  1 
ATOM   11518 C CG  . TYR C 3 691 ? 216.376 154.158 82.306  1.00 274.29 ? 714 TYR C CG  1 
ATOM   11519 C CD1 . TYR C 3 691 ? 216.710 154.743 81.092  1.00 274.29 ? 714 TYR C CD1 1 
ATOM   11520 C CD2 . TYR C 3 691 ? 217.131 154.490 83.423  1.00 274.29 ? 714 TYR C CD2 1 
ATOM   11521 C CE1 . TYR C 3 691 ? 217.761 155.635 80.995  1.00 274.29 ? 714 TYR C CE1 1 
ATOM   11522 C CE2 . TYR C 3 691 ? 218.183 155.382 83.335  1.00 274.29 ? 714 TYR C CE2 1 
ATOM   11523 C CZ  . TYR C 3 691 ? 218.493 155.951 82.119  1.00 274.29 ? 714 TYR C CZ  1 
ATOM   11524 O OH  . TYR C 3 691 ? 219.540 156.839 82.026  1.00 274.29 ? 714 TYR C OH  1 
ATOM   11525 N N   . THR C 3 692 ? 213.619 155.203 84.307  1.00 271.43 ? 715 THR C N   1 
ATOM   11526 C CA  . THR C 3 692 ? 213.641 156.408 85.125  1.00 271.43 ? 715 THR C CA  1 
ATOM   11527 C C   . THR C 3 692 ? 214.769 156.296 86.152  1.00 271.43 ? 715 THR C C   1 
ATOM   11528 O O   . THR C 3 692 ? 215.562 155.351 86.136  1.00 271.43 ? 715 THR C O   1 
ATOM   11529 C CB  . THR C 3 692 ? 212.285 156.630 85.799  1.00 271.43 ? 715 THR C CB  1 
ATOM   11530 O OG1 . THR C 3 692 ? 211.782 155.380 86.289  1.00 271.43 ? 715 THR C OG1 1 
ATOM   11531 C CG2 . THR C 3 692 ? 211.290 157.220 84.813  1.00 271.43 ? 715 THR C CG2 1 
ATOM   11532 N N   . SER C 3 693 ? 214.835 157.280 87.052  1.00 270.45 ? 716 SER C N   1 
ATOM   11533 C CA  . SER C 3 693 ? 215.852 157.268 88.097  1.00 270.45 ? 716 SER C CA  1 
ATOM   11534 C C   . SER C 3 693 ? 215.649 156.134 89.093  1.00 270.45 ? 716 SER C C   1 
ATOM   11535 O O   . SER C 3 693 ? 216.583 155.800 89.830  1.00 270.45 ? 716 SER C O   1 
ATOM   11536 C CB  . SER C 3 693 ? 215.866 158.608 88.833  1.00 270.45 ? 716 SER C CB  1 
ATOM   11537 O OG  . SER C 3 693 ? 214.633 158.841 89.491  1.00 270.45 ? 716 SER C OG  1 
ATOM   11538 N N   . ALA C 3 694 ? 214.458 155.536 89.133  1.00 270.58 ? 717 ALA C N   1 
ATOM   11539 C CA  . ALA C 3 694 ? 214.189 154.431 90.044  1.00 270.58 ? 717 ALA C CA  1 
ATOM   11540 C C   . ALA C 3 694 ? 214.493 153.073 89.429  1.00 270.58 ? 717 ALA C C   1 
ATOM   11541 O O   . ALA C 3 694 ? 214.867 152.144 90.154  1.00 270.58 ? 717 ALA C O   1 
ATOM   11542 C CB  . ALA C 3 694 ? 212.729 154.468 90.502  1.00 270.58 ? 717 ALA C CB  1 
ATOM   11543 N N   . GLY C 3 695 ? 214.342 152.935 88.114  1.00 275.10 ? 718 GLY C N   1 
ATOM   11544 C CA  . GLY C 3 695 ? 214.612 151.685 87.445  1.00 275.10 ? 718 GLY C CA  1 
ATOM   11545 C C   . GLY C 3 695 ? 213.927 151.589 86.097  1.00 275.10 ? 718 GLY C C   1 
ATOM   11546 O O   . GLY C 3 695 ? 213.176 152.481 85.689  1.00 275.10 ? 718 GLY C O   1 
ATOM   11547 N N   . PRO C 3 696 ? 214.175 150.498 85.377  1.00 279.99 ? 719 PRO C N   1 
ATOM   11548 C CA  . PRO C 3 696 ? 213.557 150.323 84.059  1.00 279.99 ? 719 PRO C CA  1 
ATOM   11549 C C   . PRO C 3 696 ? 212.085 149.960 84.180  1.00 279.99 ? 719 PRO C C   1 
ATOM   11550 O O   . PRO C 3 696 ? 211.567 149.657 85.257  1.00 279.99 ? 719 PRO C O   1 
ATOM   11551 C CB  . PRO C 3 696 ? 214.366 149.183 83.438  1.00 279.99 ? 719 PRO C CB  1 
ATOM   11552 C CG  . PRO C 3 696 ? 214.841 148.392 84.611  1.00 279.99 ? 719 PRO C CG  1 
ATOM   11553 C CD  . PRO C 3 696 ? 215.074 149.383 85.723  1.00 279.99 ? 719 PRO C CD  1 
ATOM   11554 N N   . GLY C 3 697 ? 211.406 149.994 83.036  1.00 281.29 ? 720 GLY C N   1 
ATOM   11555 C CA  . GLY C 3 697 ? 210.000 149.680 82.973  1.00 281.29 ? 720 GLY C CA  1 
ATOM   11556 C C   . GLY C 3 697 ? 209.728 148.196 83.121  1.00 281.29 ? 720 GLY C C   1 
ATOM   11557 O O   . GLY C 3 697 ? 210.621 147.404 83.439  1.00 281.29 ? 720 GLY C O   1 
ATOM   11558 N N   . PRO C 3 698 ? 208.481 147.792 82.892  1.00 282.88 ? 721 PRO C N   1 
ATOM   11559 C CA  . PRO C 3 698 ? 208.134 146.374 83.023  1.00 282.88 ? 721 PRO C CA  1 
ATOM   11560 C C   . PRO C 3 698 ? 208.696 145.551 81.876  1.00 282.88 ? 721 PRO C C   1 
ATOM   11561 O O   . PRO C 3 698 ? 208.782 146.007 80.733  1.00 282.88 ? 721 PRO C O   1 
ATOM   11562 C CB  . PRO C 3 698 ? 206.602 146.381 83.004  1.00 282.88 ? 721 PRO C CB  1 
ATOM   11563 C CG  . PRO C 3 698 ? 206.252 147.598 82.215  1.00 282.88 ? 721 PRO C CG  1 
ATOM   11564 C CD  . PRO C 3 698 ? 207.320 148.617 82.515  1.00 282.88 ? 721 PRO C CD  1 
ATOM   11565 N N   . ASN C 3 699 ? 209.083 144.319 82.198  1.00 279.48 ? 722 ASN C N   1 
ATOM   11566 C CA  . ASN C 3 699 ? 209.632 143.399 81.208  1.00 279.48 ? 722 ASN C CA  1 
ATOM   11567 C C   . ASN C 3 699 ? 208.497 142.878 80.334  1.00 279.48 ? 722 ASN C C   1 
ATOM   11568 O O   . ASN C 3 699 ? 207.631 142.135 80.806  1.00 279.48 ? 722 ASN C O   1 
ATOM   11569 C CB  . ASN C 3 699 ? 210.370 142.253 81.894  1.00 279.48 ? 722 ASN C CB  1 
ATOM   11570 C CG  . ASN C 3 699 ? 210.802 141.173 80.923  1.00 279.48 ? 722 ASN C CG  1 
ATOM   11571 O OD1 . ASN C 3 699 ? 210.295 140.052 80.956  1.00 279.48 ? 722 ASN C OD1 1 
ATOM   11572 N ND2 . ASN C 3 699 ? 211.745 141.507 80.049  1.00 279.48 ? 722 ASN C ND2 1 
ATOM   11573 N N   . GLU C 3 700 ? 208.500 143.266 79.063  1.00 281.02 ? 723 GLU C N   1 
ATOM   11574 C CA  . GLU C 3 700 ? 207.478 142.853 78.117  1.00 281.02 ? 723 GLU C CA  1 
ATOM   11575 C C   . GLU C 3 700 ? 207.988 141.688 77.272  1.00 281.02 ? 723 GLU C C   1 
ATOM   11576 O O   . GLU C 3 700 ? 209.128 141.237 77.404  1.00 281.02 ? 723 GLU C O   1 
ATOM   11577 C CB  . GLU C 3 700 ? 207.058 144.032 77.237  1.00 281.02 ? 723 GLU C CB  1 
ATOM   11578 C CG  . GLU C 3 700 ? 208.133 144.497 76.266  1.00 281.02 ? 723 GLU C CG  1 
ATOM   11579 C CD  . GLU C 3 700 ? 207.677 145.656 75.402  1.00 281.02 ? 723 GLU C CD  1 
ATOM   11580 O OE1 . GLU C 3 700 ? 206.739 146.372 75.812  1.00 281.02 ? 723 GLU C OE1 1 
ATOM   11581 O OE2 . GLU C 3 700 ? 208.256 145.851 74.313  1.00 281.02 ? 723 GLU C OE2 1 
ATOM   11582 N N   . THR C 3 701 ? 207.123 141.195 76.389  1.00 281.20 ? 724 THR C N   1 
ATOM   11583 C CA  . THR C 3 701 ? 207.491 140.096 75.513  1.00 281.20 ? 724 THR C CA  1 
ATOM   11584 C C   . THR C 3 701 ? 208.440 140.582 74.417  1.00 281.20 ? 724 THR C C   1 
ATOM   11585 O O   . THR C 3 701 ? 208.593 141.782 74.170  1.00 281.20 ? 724 THR C O   1 
ATOM   11586 C CB  . THR C 3 701 ? 206.247 139.460 74.893  1.00 281.20 ? 724 THR C CB  1 
ATOM   11587 O OG1 . THR C 3 701 ? 206.619 138.278 74.175  1.00 281.20 ? 724 THR C OG1 1 
ATOM   11588 C CG2 . THR C 3 701 ? 205.569 140.434 73.940  1.00 281.20 ? 724 THR C CG2 1 
ATOM   11589 N N   . PHE C 3 702 ? 209.083 139.625 73.755  1.00 280.38 ? 725 PHE C N   1 
ATOM   11590 C CA  . PHE C 3 702 ? 210.027 139.921 72.687  1.00 280.38 ? 725 PHE C CA  1 
ATOM   11591 C C   . PHE C 3 702 ? 209.284 140.058 71.364  1.00 280.38 ? 725 PHE C C   1 
ATOM   11592 O O   . PHE C 3 702 ? 208.440 139.221 71.028  1.00 280.38 ? 725 PHE C O   1 
ATOM   11593 C CB  . PHE C 3 702 ? 211.089 138.825 72.586  1.00 280.38 ? 725 PHE C CB  1 
ATOM   11594 C CG  . PHE C 3 702 ? 212.123 138.878 73.675  1.00 280.38 ? 725 PHE C CG  1 
ATOM   11595 C CD1 . PHE C 3 702 ? 213.375 139.420 73.435  1.00 280.38 ? 725 PHE C CD1 1 
ATOM   11596 C CD2 . PHE C 3 702 ? 211.843 138.385 74.939  1.00 280.38 ? 725 PHE C CD2 1 
ATOM   11597 C CE1 . PHE C 3 702 ? 214.329 139.469 74.434  1.00 280.38 ? 725 PHE C CE1 1 
ATOM   11598 C CE2 . PHE C 3 702 ? 212.792 138.432 75.943  1.00 280.38 ? 725 PHE C CE2 1 
ATOM   11599 C CZ  . PHE C 3 702 ? 214.037 138.974 75.690  1.00 280.38 ? 725 PHE C CZ  1 
ATOM   11600 N N   . THR C 3 703 ? 209.600 141.115 70.619  1.00 277.30 ? 726 THR C N   1 
ATOM   11601 C CA  . THR C 3 703 ? 208.968 141.334 69.325  1.00 277.30 ? 726 THR C CA  1 
ATOM   11602 C C   . THR C 3 703 ? 209.501 140.336 68.306  1.00 277.30 ? 726 THR C C   1 
ATOM   11603 O O   . THR C 3 703 ? 210.714 140.130 68.197  1.00 277.30 ? 726 THR C O   1 
ATOM   11604 C CB  . THR C 3 703 ? 209.214 142.764 68.846  1.00 277.30 ? 726 THR C CB  1 
ATOM   11605 O OG1 . THR C 3 703 ? 208.961 143.680 69.919  1.00 277.30 ? 726 THR C OG1 1 
ATOM   11606 C CG2 . THR C 3 703 ? 208.299 143.099 67.677  1.00 277.30 ? 726 THR C CG2 1 
ATOM   11607 N N   . LYS C 3 704 ? 208.592 139.717 67.556  1.00 272.73 ? 727 LYS C N   1 
ATOM   11608 C CA  . LYS C 3 704 ? 208.949 138.698 66.576  1.00 272.73 ? 727 LYS C CA  1 
ATOM   11609 C C   . LYS C 3 704 ? 209.312 139.382 65.263  1.00 272.73 ? 727 LYS C C   1 
ATOM   11610 O O   . LYS C 3 704 ? 208.451 139.971 64.601  1.00 272.73 ? 727 LYS C O   1 
ATOM   11611 C CB  . LYS C 3 704 ? 207.800 137.710 66.385  1.00 272.73 ? 727 LYS C CB  1 
ATOM   11612 C CG  . LYS C 3 704 ? 208.118 136.521 65.482  1.00 272.73 ? 727 LYS C CG  1 
ATOM   11613 C CD  . LYS C 3 704 ? 209.562 136.055 65.624  1.00 272.73 ? 727 LYS C CD  1 
ATOM   11614 C CE  . LYS C 3 704 ? 209.739 135.143 66.828  1.00 272.73 ? 727 LYS C CE  1 
ATOM   11615 N NZ  . LYS C 3 704 ? 211.005 134.363 66.747  1.00 272.73 ? 727 LYS C NZ  1 
ATOM   11616 N N   . VAL C 3 705 ? 210.587 139.306 64.888  1.00 278.41 ? 728 VAL C N   1 
ATOM   11617 C CA  . VAL C 3 705 ? 211.080 139.853 63.632  1.00 278.41 ? 728 VAL C CA  1 
ATOM   11618 C C   . VAL C 3 705 ? 211.918 138.788 62.938  1.00 278.41 ? 728 VAL C C   1 
ATOM   11619 O O   . VAL C 3 705 ? 212.579 137.978 63.597  1.00 278.41 ? 728 VAL C O   1 
ATOM   11620 C CB  . VAL C 3 705 ? 211.905 141.139 63.847  1.00 278.41 ? 728 VAL C CB  1 
ATOM   11621 C CG1 . VAL C 3 705 ? 210.988 142.311 64.160  1.00 278.41 ? 728 VAL C CG1 1 
ATOM   11622 C CG2 . VAL C 3 705 ? 212.923 140.938 64.959  1.00 278.41 ? 728 VAL C CG2 1 
ATOM   11623 N N   . THR C 3 706 ? 211.886 138.789 61.608  1.00 289.19 ? 729 THR C N   1 
ATOM   11624 C CA  . THR C 3 706 ? 212.630 137.832 60.798  1.00 289.19 ? 729 THR C CA  1 
ATOM   11625 C C   . THR C 3 706 ? 213.543 138.597 59.851  1.00 289.19 ? 729 THR C C   1 
ATOM   11626 O O   . THR C 3 706 ? 213.072 139.425 59.064  1.00 289.19 ? 729 THR C O   1 
ATOM   11627 C CB  . THR C 3 706 ? 211.685 136.919 60.013  1.00 289.19 ? 729 THR C CB  1 
ATOM   11628 O OG1 . THR C 3 706 ? 210.827 136.220 60.924  1.00 289.19 ? 729 THR C OG1 1 
ATOM   11629 C CG2 . THR C 3 706 ? 212.477 135.909 59.195  1.00 289.19 ? 729 THR C CG2 1 
ATOM   11630 N N   . THR C 3 707 ? 214.843 138.320 59.931  1.00 301.12 ? 730 THR C N   1 
ATOM   11631 C CA  . THR C 3 707 ? 215.817 138.977 59.070  1.00 301.12 ? 730 THR C CA  1 
ATOM   11632 C C   . THR C 3 707 ? 216.060 138.125 57.831  1.00 301.12 ? 730 THR C C   1 
ATOM   11633 O O   . THR C 3 707 ? 216.416 136.947 57.966  1.00 301.12 ? 730 THR C O   1 
ATOM   11634 C CB  . THR C 3 707 ? 217.126 139.200 59.809  1.00 301.12 ? 730 THR C CB  1 
ATOM   11635 O OG1 . THR C 3 707 ? 216.855 139.710 61.121  1.00 301.12 ? 730 THR C OG1 1 
ATOM   11636 C CG2 . THR C 3 707 ? 218.000 140.192 59.057  1.00 301.12 ? 730 THR C CG2 1 
ATOM   11637 N N   . PRO C 3 708 ? 215.883 138.667 56.617  1.00 306.11 ? 731 PRO C N   1 
ATOM   11638 C CA  . PRO C 3 708 ? 216.102 137.916 55.377  1.00 306.11 ? 731 PRO C CA  1 
ATOM   11639 C C   . PRO C 3 708 ? 217.581 137.660 55.101  1.00 306.11 ? 731 PRO C C   1 
ATOM   11640 O O   . PRO C 3 708 ? 218.417 138.439 55.558  1.00 306.11 ? 731 PRO C O   1 
ATOM   11641 C CB  . PRO C 3 708 ? 215.499 138.827 54.306  1.00 306.11 ? 731 PRO C CB  1 
ATOM   11642 C CG  . PRO C 3 708 ? 215.625 140.197 54.874  1.00 306.11 ? 731 PRO C CG  1 
ATOM   11643 C CD  . PRO C 3 708 ? 215.436 140.046 56.357  1.00 306.11 ? 731 PRO C CD  1 
HETATM 11644 C C1  . NAG D 4 .   ? 119.499 202.050 137.462 1.00 231.43 ? 1   NAG D C1  1 
HETATM 11645 C C2  . NAG D 4 .   ? 119.141 202.150 138.953 1.00 231.43 ? 1   NAG D C2  1 
HETATM 11646 C C3  . NAG D 4 .   ? 118.888 200.763 139.554 1.00 231.43 ? 1   NAG D C3  1 
HETATM 11647 C C4  . NAG D 4 .   ? 120.075 199.831 139.337 1.00 231.43 ? 1   NAG D C4  1 
HETATM 11648 C C5  . NAG D 4 .   ? 120.703 200.067 137.970 1.00 231.43 ? 1   NAG D C5  1 
HETATM 11649 C C6  . NAG D 4 .   ? 121.125 198.788 137.285 0.10 231.43 ? 1   NAG D C6  1 
HETATM 11650 C C7  . NAG D 4 .   ? 119.957 203.996 140.349 0.10 231.43 ? 1   NAG D C7  1 
HETATM 11651 C C8  . NAG D 4 .   ? 121.138 204.581 141.063 0.10 231.43 ? 1   NAG D C8  1 
HETATM 11652 N N2  . NAG D 4 .   ? 120.176 202.850 139.696 0.10 231.43 ? 1   NAG D N2  1 
HETATM 11653 O O3  . NAG D 4 .   ? 117.718 200.202 138.970 1.00 231.43 ? 1   NAG D O3  1 
HETATM 11654 O O4  . NAG D 4 .   ? 121.053 200.041 140.350 1.00 231.43 ? 1   NAG D O4  1 
HETATM 11655 O O5  . NAG D 4 .   ? 119.739 200.694 137.116 1.00 231.43 ? 1   NAG D O5  1 
HETATM 11656 O O6  . NAG D 4 .   ? 120.779 198.798 135.907 0.10 231.43 ? 1   NAG D O6  1 
HETATM 11657 O O7  . NAG D 4 .   ? 118.855 204.536 140.362 0.10 231.43 ? 1   NAG D O7  1 
HETATM 11658 C C1  . NAG D 4 .   ? 120.640 199.326 141.532 1.00 231.02 ? 2   NAG D C1  1 
HETATM 11659 C C2  . NAG D 4 .   ? 121.726 198.308 141.897 1.00 231.02 ? 2   NAG D C2  1 
HETATM 11660 C C3  . NAG D 4 .   ? 121.357 197.572 143.184 1.00 231.02 ? 2   NAG D C3  1 
HETATM 11661 C C4  . NAG D 4 .   ? 121.045 198.566 144.295 1.00 231.02 ? 2   NAG D C4  1 
HETATM 11662 C C5  . NAG D 4 .   ? 119.987 199.563 143.831 1.00 231.02 ? 2   NAG D C5  1 
HETATM 11663 C C6  . NAG D 4 .   ? 119.709 200.647 144.846 1.00 231.02 ? 2   NAG D C6  1 
HETATM 11664 C C7  . NAG D 4 .   ? 121.051 196.528 140.316 1.00 231.02 ? 2   NAG D C7  1 
HETATM 11665 C C8  . NAG D 4 .   ? 121.513 195.641 139.199 1.00 231.02 ? 2   NAG D C8  1 
HETATM 11666 N N2  . NAG D 4 .   ? 121.969 197.368 140.812 1.00 231.02 ? 2   NAG D N2  1 
HETATM 11667 O O3  . NAG D 4 .   ? 122.435 196.729 143.573 1.00 231.02 ? 2   NAG D O3  1 
HETATM 11668 O O4  . NAG D 4 .   ? 120.566 197.875 145.444 1.00 231.02 ? 2   NAG D O4  1 
HETATM 11669 O O5  . NAG D 4 .   ? 120.427 200.220 142.633 1.00 231.02 ? 2   NAG D O5  1 
HETATM 11670 O O6  . NAG D 4 .   ? 120.625 200.591 145.931 1.00 231.02 ? 2   NAG D O6  1 
HETATM 11671 O O7  . NAG D 4 .   ? 119.900 196.483 140.744 1.00 231.02 ? 2   NAG D O7  1 
HETATM 11672 C C1  . NAG E 4 .   ? 180.931 120.091 74.534  1.00 261.81 ? 1   NAG E C1  1 
HETATM 11673 C C2  . NAG E 4 .   ? 179.742 120.461 73.655  1.00 261.81 ? 1   NAG E C2  1 
HETATM 11674 C C3  . NAG E 4 .   ? 179.265 121.872 73.987  1.00 261.81 ? 1   NAG E C3  1 
HETATM 11675 C C4  . NAG E 4 .   ? 178.992 122.009 75.480  1.00 261.81 ? 1   NAG E C4  1 
HETATM 11676 C C5  . NAG E 4 .   ? 180.197 121.537 76.293  1.00 261.81 ? 1   NAG E C5  1 
HETATM 11677 C C6  . NAG E 4 .   ? 179.932 121.504 77.780  1.00 261.81 ? 1   NAG E C6  1 
HETATM 11678 C C7  . NAG E 4 .   ? 179.444 119.533 71.403  1.00 261.81 ? 1   NAG E C7  1 
HETATM 11679 C C8  . NAG E 4 .   ? 179.923 119.549 69.982  1.00 261.81 ? 1   NAG E C8  1 
HETATM 11680 N N2  . NAG E 4 .   ? 180.080 120.354 72.245  1.00 261.81 ? 1   NAG E N2  1 
HETATM 11681 O O3  . NAG E 4 .   ? 178.083 122.159 73.247  1.00 261.81 ? 1   NAG E O3  1 
HETATM 11682 O O4  . NAG E 4 .   ? 178.732 123.373 75.794  1.00 261.81 ? 1   NAG E O4  1 
HETATM 11683 O O5  . NAG E 4 .   ? 180.563 120.204 75.909  1.00 261.81 ? 1   NAG E O5  1 
HETATM 11684 O O6  . NAG E 4 .   ? 180.105 120.196 78.310  1.00 261.81 ? 1   NAG E O6  1 
HETATM 11685 O O7  . NAG E 4 .   ? 178.524 118.809 71.771  1.00 261.81 ? 1   NAG E O7  1 
HETATM 11686 C C1  . NAG E 4 .   ? 177.364 123.525 76.229  0.50 252.77 ? 2   NAG E C1  1 
HETATM 11687 C C2  . NAG E 4 .   ? 177.095 125.021 76.403  0.50 252.77 ? 2   NAG E C2  1 
HETATM 11688 C C3  . NAG E 4 .   ? 175.761 125.412 75.762  0.50 252.77 ? 2   NAG E C3  1 
HETATM 11689 C C4  . NAG E 4 .   ? 174.663 124.401 76.079  0.50 252.77 ? 2   NAG E C4  1 
HETATM 11690 C C5  . NAG E 4 .   ? 175.114 122.976 75.772  0.50 252.77 ? 2   NAG E C5  1 
HETATM 11691 C C6  . NAG E 4 .   ? 174.271 122.303 74.714  0.50 252.77 ? 2   NAG E C6  1 
HETATM 11692 C C7  . NAG E 4 .   ? 178.241 125.684 78.470  0.50 252.77 ? 2   NAG E C7  1 
HETATM 11693 C C8  . NAG E 4 .   ? 178.078 126.050 79.915  0.50 252.77 ? 2   NAG E C8  1 
HETATM 11694 N N2  . NAG E 4 .   ? 177.116 125.395 77.808  0.50 252.77 ? 2   NAG E N2  1 
HETATM 11695 O O3  . NAG E 4 .   ? 175.928 125.520 74.353  0.50 252.77 ? 2   NAG E O3  1 
HETATM 11696 O O4  . NAG E 4 .   ? 174.304 124.491 77.453  0.50 252.77 ? 2   NAG E O4  1 
HETATM 11697 O O5  . NAG E 4 .   ? 176.460 122.987 75.282  0.50 252.77 ? 2   NAG E O5  1 
HETATM 11698 O O6  . NAG E 4 .   ? 174.610 120.931 74.574  0.50 252.77 ? 2   NAG E O6  1 
HETATM 11699 O O7  . NAG E 4 .   ? 179.342 125.652 77.928  0.50 252.77 ? 2   NAG E O7  1 
HETATM 11700 C C1  . NAG F 4 .   ? 119.841 185.569 122.756 1.00 208.36 ? 1   NAG F C1  1 
HETATM 11701 C C2  . NAG F 4 .   ? 119.722 186.979 122.170 1.00 208.36 ? 1   NAG F C2  1 
HETATM 11702 C C3  . NAG F 4 .   ? 120.163 186.998 120.704 1.00 208.36 ? 1   NAG F C3  1 
HETATM 11703 C C4  . NAG F 4 .   ? 119.491 185.890 119.901 1.00 208.36 ? 1   NAG F C4  1 
HETATM 11704 C C5  . NAG F 4 .   ? 119.578 184.555 120.634 1.00 208.36 ? 1   NAG F C5  1 
HETATM 11705 C C6  . NAG F 4 .   ? 120.185 183.457 119.793 0.00 208.36 ? 1   NAG F C6  1 
HETATM 11706 C C7  . NAG F 4 .   ? 118.079 188.676 122.838 0.00 208.36 ? 1   NAG F C7  1 
HETATM 11707 C C8  . NAG F 4 .   ? 116.626 189.038 122.895 0.00 208.36 ? 1   NAG F C8  1 
HETATM 11708 N N2  . NAG F 4 .   ? 118.365 187.485 122.302 1.00 208.36 ? 1   NAG F N2  1 
HETATM 11709 O O3  . NAG F 4 .   ? 121.577 186.857 120.635 1.00 208.36 ? 1   NAG F O3  1 
HETATM 11710 O O4  . NAG F 4 .   ? 118.122 186.212 119.682 0.50 208.36 ? 1   NAG F O4  1 
HETATM 11711 O O5  . NAG F 4 .   ? 120.410 184.698 121.792 1.00 208.36 ? 1   NAG F O5  1 
HETATM 11712 O O6  . NAG F 4 .   ? 119.338 182.318 119.736 0.00 208.36 ? 1   NAG F O6  1 
HETATM 11713 O O7  . NAG F 4 .   ? 118.954 189.427 123.258 0.00 208.36 ? 1   NAG F O7  1 
HETATM 11714 C C1  . NAG F 4 .   ? 117.944 186.750 118.354 0.50 220.63 ? 2   NAG F C1  1 
HETATM 11715 C C2  . NAG F 4 .   ? 117.489 188.208 118.482 0.50 220.63 ? 2   NAG F C2  1 
HETATM 11716 C C3  . NAG F 4 .   ? 117.330 188.841 117.102 0.50 220.63 ? 2   NAG F C3  1 
HETATM 11717 C C4  . NAG F 4 .   ? 118.605 188.669 116.287 1.00 220.63 ? 2   NAG F C4  1 
HETATM 11718 C C5  . NAG F 4 .   ? 119.010 187.198 116.242 1.00 220.63 ? 2   NAG F C5  1 
HETATM 11719 C C6  . NAG F 4 .   ? 120.331 186.970 115.544 1.00 220.63 ? 2   NAG F C6  1 
HETATM 11720 C C7  . NAG F 4 .   ? 115.090 187.764 118.903 1.00 220.63 ? 2   NAG F C7  1 
HETATM 11721 C C8  . NAG F 4 .   ? 113.946 188.006 119.841 1.00 220.63 ? 2   NAG F C8  1 
HETATM 11722 N N2  . NAG F 4 .   ? 116.258 188.321 119.252 1.00 220.63 ? 2   NAG F N2  1 
HETATM 11723 O O3  . NAG F 4 .   ? 117.027 190.224 117.247 1.00 220.63 ? 2   NAG F O3  1 
HETATM 11724 O O4  . NAG F 4 .   ? 118.403 189.141 114.960 0.50 220.63 ? 2   NAG F O4  1 
HETATM 11725 O O5  . NAG F 4 .   ? 119.154 186.689 117.576 0.50 220.63 ? 2   NAG F O5  1 
HETATM 11726 O O6  . NAG F 4 .   ? 121.421 187.423 116.336 1.00 220.63 ? 2   NAG F O6  1 
HETATM 11727 O O7  . NAG F 4 .   ? 114.959 187.096 117.880 1.00 220.63 ? 2   NAG F O7  1 
HETATM 11728 C C1  . NAG G 4 .   ? 136.342 151.613 130.165 1.00 108.98 ? 1   NAG G C1  1 
HETATM 11729 C C2  . NAG G 4 .   ? 136.616 150.503 129.148 1.00 108.98 ? 1   NAG G C2  1 
HETATM 11730 C C3  . NAG G 4 .   ? 138.099 150.471 128.761 1.00 108.98 ? 1   NAG G C3  1 
HETATM 11731 C C4  . NAG G 4 .   ? 139.005 150.527 129.987 1.00 108.98 ? 1   NAG G C4  1 
HETATM 11732 C C5  . NAG G 4 .   ? 138.567 151.632 130.943 1.00 108.98 ? 1   NAG G C5  1 
HETATM 11733 C C6  . NAG G 4 .   ? 139.673 152.609 131.267 0.00 108.98 ? 1   NAG G C6  1 
HETATM 11734 C C7  . NAG G 4 .   ? 135.183 148.511 129.132 0.00 108.98 ? 1   NAG G C7  1 
HETATM 11735 C C8  . NAG G 4 .   ? 134.882 147.196 129.785 0.00 108.98 ? 1   NAG G C8  1 
HETATM 11736 N N2  . NAG G 4 .   ? 136.193 149.210 129.659 1.00 108.98 ? 1   NAG G N2  1 
HETATM 11737 O O3  . NAG G 4 .   ? 138.385 151.565 127.896 1.00 108.98 ? 1   NAG G O3  1 
HETATM 11738 O O4  . NAG G 4 .   ? 138.975 149.277 130.669 0.50 108.98 ? 1   NAG G O4  1 
HETATM 11739 O O5  . NAG G 4 .   ? 137.509 152.391 130.346 1.00 108.98 ? 1   NAG G O5  1 
HETATM 11740 O O6  . NAG G 4 .   ? 139.925 152.662 132.665 0.00 108.98 ? 1   NAG G O6  1 
HETATM 11741 O O7  . NAG G 4 .   ? 134.540 148.922 128.171 0.00 108.98 ? 1   NAG G O7  1 
HETATM 11742 C C1  . NAG G 4 .   ? 140.316 148.757 130.801 0.50 118.92 ? 2   NAG G C1  1 
HETATM 11743 C C2  . NAG G 4 .   ? 140.697 148.037 129.503 0.50 118.92 ? 2   NAG G C2  1 
HETATM 11744 C C3  . NAG G 4 .   ? 142.132 147.518 129.581 0.50 118.92 ? 2   NAG G C3  1 
HETATM 11745 C C4  . NAG G 4 .   ? 143.085 148.644 129.960 1.00 118.92 ? 2   NAG G C4  1 
HETATM 11746 C C5  . NAG G 4 .   ? 142.612 149.330 131.239 1.00 118.92 ? 2   NAG G C5  1 
HETATM 11747 C C6  . NAG G 4 .   ? 143.451 150.530 131.612 1.00 118.92 ? 2   NAG G C6  1 
HETATM 11748 C C7  . NAG G 4 .   ? 139.563 145.887 129.971 1.00 118.92 ? 2   NAG G C7  1 
HETATM 11749 C C8  . NAG G 4 .   ? 138.563 144.894 129.462 1.00 118.92 ? 2   NAG G C8  1 
HETATM 11750 N N2  . NAG G 4 .   ? 139.770 146.958 129.193 1.00 118.92 ? 2   NAG G N2  1 
HETATM 11751 O O3  . NAG G 4 .   ? 142.506 146.966 128.324 1.00 118.92 ? 2   NAG G O3  1 
HETATM 11752 O O4  . NAG G 4 .   ? 144.394 148.125 130.163 0.50 118.92 ? 2   NAG G O4  1 
HETATM 11753 O O5  . NAG G 4 .   ? 141.267 149.801 131.071 0.50 118.92 ? 2   NAG G O5  1 
HETATM 11754 O O6  . NAG G 4 .   ? 142.896 151.732 131.097 1.00 118.92 ? 2   NAG G O6  1 
HETATM 11755 O O7  . NAG G 4 .   ? 140.154 145.724 131.037 1.00 118.92 ? 2   NAG G O7  1 
HETATM 11756 C C1  . NAG H 4 .   ? 124.436 212.163 132.091 1.00 251.52 ? 1   NAG H C1  1 
HETATM 11757 C C2  . NAG H 4 .   ? 125.064 213.556 132.216 1.00 251.52 ? 1   NAG H C2  1 
HETATM 11758 C C3  . NAG H 4 .   ? 125.458 214.099 130.840 1.00 251.52 ? 1   NAG H C3  1 
HETATM 11759 C C4  . NAG H 4 .   ? 124.364 213.863 129.803 1.00 251.52 ? 1   NAG H C4  1 
HETATM 11760 C C5  . NAG H 4 .   ? 123.895 212.410 129.809 1.00 251.52 ? 1   NAG H C5  1 
HETATM 11761 C C6  . NAG H 4 .   ? 124.091 211.720 128.479 0.10 251.52 ? 1   NAG H C6  1 
HETATM 11762 C C7  . NAG H 4 .   ? 124.589 215.483 133.659 0.10 251.52 ? 1   NAG H C7  1 
HETATM 11763 C C8  . NAG H 4 .   ? 123.522 216.335 134.278 0.10 251.52 ? 1   NAG H C8  1 
HETATM 11764 N N2  . NAG H 4 .   ? 124.162 214.476 132.890 0.10 251.52 ? 1   NAG H N2  1 
HETATM 11765 O O3  . NAG H 4 .   ? 126.668 213.481 130.417 1.00 251.52 ? 1   NAG H O3  1 
HETATM 11766 O O4  . NAG H 4 .   ? 123.254 214.713 130.067 1.00 251.52 ? 1   NAG H O4  1 
HETATM 11767 O O5  . NAG H 4 .   ? 124.640 211.663 130.778 1.00 251.52 ? 1   NAG H O5  1 
HETATM 11768 O O6  . NAG H 4 .   ? 122.931 210.994 128.095 0.10 251.52 ? 1   NAG H O6  1 
HETATM 11769 O O7  . NAG H 4 .   ? 125.782 215.697 133.848 0.10 251.52 ? 1   NAG H O7  1 
HETATM 11770 C C1  . NAG H 4 .   ? 123.324 215.848 129.181 1.00 254.91 ? 2   NAG H C1  1 
HETATM 11771 C C2  . NAG H 4 .   ? 121.929 216.109 128.606 1.00 254.91 ? 2   NAG H C2  1 
HETATM 11772 C C3  . NAG H 4 .   ? 121.944 217.344 127.708 1.00 254.91 ? 2   NAG H C3  1 
HETATM 11773 C C4  . NAG H 4 .   ? 122.533 218.535 128.453 1.00 254.91 ? 2   NAG H C4  1 
HETATM 11774 C C5  . NAG H 4 .   ? 123.900 218.176 129.028 1.00 254.91 ? 2   NAG H C5  1 
HETATM 11775 C C6  . NAG H 4 .   ? 124.492 219.276 129.878 1.00 254.91 ? 2   NAG H C6  1 
HETATM 11776 C C7  . NAG H 4 .   ? 121.994 214.413 126.804 1.00 254.91 ? 2   NAG H C7  1 
HETATM 11777 C C8  . NAG H 4 .   ? 121.299 213.221 126.219 1.00 254.91 ? 2   NAG H C8  1 
HETATM 11778 N N2  . NAG H 4 .   ? 121.417 214.950 127.888 1.00 254.91 ? 2   NAG H N2  1 
HETATM 11779 O O3  . NAG H 4 .   ? 120.618 217.641 127.285 1.00 254.91 ? 2   NAG H O3  1 
HETATM 11780 O O4  . NAG H 4 .   ? 122.671 219.642 127.569 1.00 254.91 ? 2   NAG H O4  1 
HETATM 11781 O O5  . NAG H 4 .   ? 123.788 217.018 129.869 1.00 254.91 ? 2   NAG H O5  1 
HETATM 11782 O O6  . NAG H 4 .   ? 124.395 218.970 131.263 1.00 254.91 ? 2   NAG H O6  1 
HETATM 11783 O O7  . NAG H 4 .   ? 123.026 214.866 126.315 1.00 254.91 ? 2   NAG H O7  1 
HETATM 11784 C C1  . NAG I 4 .   ? 162.868 144.915 220.182 1.00 97.64  ? 1   NAG I C1  1 
HETATM 11785 C C2  . NAG I 4 .   ? 162.602 143.980 219.000 1.00 97.64  ? 1   NAG I C2  1 
HETATM 11786 C C3  . NAG I 4 .   ? 163.812 143.929 218.060 1.00 97.64  ? 1   NAG I C3  1 
HETATM 11787 C C4  . NAG I 4 .   ? 165.127 143.832 218.829 1.00 97.64  ? 1   NAG I C4  1 
HETATM 11788 C C5  . NAG I 4 .   ? 165.204 144.876 219.940 1.00 97.64  ? 1   NAG I C5  1 
HETATM 11789 C C6  . NAG I 4 .   ? 166.379 145.815 219.792 0.10 97.64  ? 1   NAG I C6  1 
HETATM 11790 C C7  . NAG I 4 .   ? 161.594 141.759 218.713 0.10 97.64  ? 1   NAG I C7  1 
HETATM 11791 C C8  . NAG I 4 .   ? 161.327 140.429 219.351 0.10 97.64  ? 1   NAG I C8  1 
HETATM 11792 N N2  . NAG I 4 .   ? 162.259 142.644 219.462 0.10 97.64  ? 1   NAG I N2  1 
HETATM 11793 O O3  . NAG I 4 .   ? 163.817 145.085 217.230 1.00 97.64  ? 1   NAG I O3  1 
HETATM 11794 O O4  . NAG I 4 .   ? 165.265 142.535 219.398 1.00 97.64  ? 1   NAG I O4  1 
HETATM 11795 O O5  . NAG I 4 .   ? 164.022 145.685 219.926 1.00 97.64  ? 1   NAG I O5  1 
HETATM 11796 O O6  . NAG I 4 .   ? 166.814 145.893 218.442 0.10 97.64  ? 1   NAG I O6  1 
HETATM 11797 O O7  . NAG I 4 .   ? 161.223 142.019 217.573 0.10 97.64  ? 1   NAG I O7  1 
HETATM 11798 C C1  . NAG I 4 .   ? 165.821 141.643 218.412 1.00 108.90 ? 2   NAG I C1  1 
HETATM 11799 C C2  . NAG I 4 .   ? 167.159 141.105 218.929 1.00 108.90 ? 2   NAG I C2  1 
HETATM 11800 C C3  . NAG I 4 .   ? 167.745 140.091 217.948 1.00 108.90 ? 2   NAG I C3  1 
HETATM 11801 C C4  . NAG I 4 .   ? 166.726 139.004 217.633 1.00 108.90 ? 2   NAG I C4  1 
HETATM 11802 C C5  . NAG I 4 .   ? 165.419 139.631 217.158 1.00 108.90 ? 2   NAG I C5  1 
HETATM 11803 C C6  . NAG I 4 .   ? 164.324 138.615 216.930 1.00 108.90 ? 2   NAG I C6  1 
HETATM 11804 C C7  . NAG I 4 .   ? 168.577 143.020 218.259 1.00 108.90 ? 2   NAG I C7  1 
HETATM 11805 C C8  . NAG I 4 .   ? 169.547 144.055 218.744 1.00 108.90 ? 2   NAG I C8  1 
HETATM 11806 N N2  . NAG I 4 .   ? 168.106 142.180 219.191 1.00 108.90 ? 2   NAG I N2  1 
HETATM 11807 O O3  . NAG I 4 .   ? 168.917 139.512 218.509 1.00 108.90 ? 2   NAG I O3  1 
HETATM 11808 O O4  . NAG I 4 .   ? 167.231 138.143 216.619 1.00 108.90 ? 2   NAG I O4  1 
HETATM 11809 O O5  . NAG I 4 .   ? 164.932 140.550 218.147 1.00 108.90 ? 2   NAG I O5  1 
HETATM 11810 O O6  . NAG I 4 .   ? 164.771 137.296 217.215 1.00 108.90 ? 2   NAG I O6  1 
HETATM 11811 O O7  . NAG I 4 .   ? 168.237 142.952 217.080 1.00 108.90 ? 2   NAG I O7  1 
HETATM 11812 C C1  . NAG J 4 .   ? 171.942 148.195 195.795 1.00 89.43  ? 1   NAG J C1  1 
HETATM 11813 C C2  . NAG J 4 .   ? 172.949 149.357 195.843 1.00 89.43  ? 1   NAG J C2  1 
HETATM 11814 C C3  . NAG J 4 .   ? 173.788 149.312 197.126 1.00 89.43  ? 1   NAG J C3  1 
HETATM 11815 C C4  . NAG J 4 .   ? 174.509 147.978 197.286 1.00 89.43  ? 1   NAG J C4  1 
HETATM 11816 C C5  . NAG J 4 .   ? 173.677 146.843 196.703 1.00 89.43  ? 1   NAG J C5  1 
HETATM 11817 C C6  . NAG J 4 .   ? 173.818 145.551 197.472 0.10 89.43  ? 1   NAG J C6  1 
HETATM 11818 C C7  . NAG J 4 .   ? 173.691 150.251 193.681 0.10 89.43  ? 1   NAG J C7  1 
HETATM 11819 C C8  . NAG J 4 .   ? 174.658 150.103 192.545 0.10 89.43  ? 1   NAG J C8  1 
HETATM 11820 N N2  . NAG J 4 .   ? 173.807 149.358 194.669 0.10 89.43  ? 1   NAG J N2  1 
HETATM 11821 O O3  . NAG J 4 .   ? 172.946 149.546 198.249 1.00 89.43  ? 1   NAG J O3  1 
HETATM 11822 O O4  . NAG J 4 .   ? 175.776 148.020 196.640 1.00 89.43  ? 1   NAG J O4  1 
HETATM 11823 O O5  . NAG J 4 .   ? 172.294 147.211 196.760 1.00 89.43  ? 1   NAG J O5  1 
HETATM 11824 O O6  . NAG J 4 .   ? 173.200 145.636 198.749 0.10 89.43  ? 1   NAG J O6  1 
HETATM 11825 O O7  . NAG J 4 .   ? 172.844 151.139 193.703 0.10 89.43  ? 1   NAG J O7  1 
HETATM 11826 C C1  . NAG J 4 .   ? 176.693 148.753 197.478 1.00 113.21 ? 2   NAG J C1  1 
HETATM 11827 C C2  . NAG J 4 .   ? 177.781 147.799 197.984 1.00 113.21 ? 2   NAG J C2  1 
HETATM 11828 C C3  . NAG J 4 .   ? 178.813 148.558 198.816 1.00 113.21 ? 2   NAG J C3  1 
HETATM 11829 C C4  . NAG J 4 .   ? 179.353 149.751 198.038 1.00 113.21 ? 2   NAG J C4  1 
HETATM 11830 C C5  . NAG J 4 .   ? 178.202 150.623 197.543 1.00 113.21 ? 2   NAG J C5  1 
HETATM 11831 C C6  . NAG J 4 .   ? 178.661 151.765 196.667 1.00 113.21 ? 2   NAG J C6  1 
HETATM 11832 C C7  . NAG J 4 .   ? 176.520 146.823 199.878 1.00 113.21 ? 2   NAG J C7  1 
HETATM 11833 C C8  . NAG J 4 .   ? 176.031 145.548 200.496 1.00 113.21 ? 2   NAG J C8  1 
HETATM 11834 N N2  . NAG J 4 .   ? 177.217 146.690 198.741 1.00 113.21 ? 2   NAG J N2  1 
HETATM 11835 O O3  . NAG J 4 .   ? 179.878 147.682 199.166 1.00 113.21 ? 2   NAG J O3  1 
HETATM 11836 O O4  . NAG J 4 .   ? 180.205 150.529 198.871 1.00 113.21 ? 2   NAG J O4  1 
HETATM 11837 O O5  . NAG J 4 .   ? 177.297 149.835 196.756 1.00 113.21 ? 2   NAG J O5  1 
HETATM 11838 O O6  . NAG J 4 .   ? 179.384 151.295 195.538 1.00 113.21 ? 2   NAG J O6  1 
HETATM 11839 O O7  . NAG J 4 .   ? 176.291 147.919 200.384 1.00 113.21 ? 2   NAG J O7  1 
HETATM 11840 C C1  . NAG K 4 .   ? 155.723 168.371 179.781 1.00 67.23  ? 1   NAG K C1  1 
HETATM 11841 C C2  . NAG K 4 .   ? 155.257 168.929 181.133 1.00 67.23  ? 1   NAG K C2  1 
HETATM 11842 C C3  . NAG K 4 .   ? 154.137 169.960 180.951 1.00 67.23  ? 1   NAG K C3  1 
HETATM 11843 C C4  . NAG K 4 .   ? 152.993 169.413 180.103 1.00 67.23  ? 1   NAG K C4  1 
HETATM 11844 C C5  . NAG K 4 .   ? 153.525 168.585 178.941 1.00 67.23  ? 1   NAG K C5  1 
HETATM 11845 C C6  . NAG K 4 .   ? 152.826 168.880 177.635 0.10 67.23  ? 1   NAG K C6  1 
HETATM 11846 C C7  . NAG K 4 .   ? 155.666 167.214 182.839 0.10 67.23  ? 1   NAG K C7  1 
HETATM 11847 C C8  . NAG K 4 .   ? 155.057 166.138 183.686 0.10 67.23  ? 1   NAG K C8  1 
HETATM 11848 N N2  . NAG K 4 .   ? 154.829 167.860 182.020 0.10 67.23  ? 1   NAG K N2  1 
HETATM 11849 O O3  . NAG K 4 .   ? 154.670 171.133 180.346 1.00 67.23  ? 1   NAG K O3  1 
HETATM 11850 O O4  . NAG K 4 .   ? 152.132 168.609 180.901 1.00 67.23  ? 1   NAG K O4  1 
HETATM 11851 O O5  . NAG K 4 .   ? 154.910 168.888 178.746 1.00 67.23  ? 1   NAG K O5  1 
HETATM 11852 O O6  . NAG K 4 .   ? 153.064 170.214 177.207 0.10 67.23  ? 1   NAG K O6  1 
HETATM 11853 O O7  . NAG K 4 .   ? 156.861 167.486 182.892 0.10 67.23  ? 1   NAG K O7  1 
HETATM 11854 C C1  . NAG K 4 .   ? 151.230 169.473 181.621 1.00 80.77  ? 2   NAG K C1  1 
HETATM 11855 C C2  . NAG K 4 .   ? 149.794 169.177 181.175 1.00 80.77  ? 2   NAG K C2  1 
HETATM 11856 C C3  . NAG K 4 .   ? 148.802 170.024 181.970 1.00 80.77  ? 2   NAG K C3  1 
HETATM 11857 C C4  . NAG K 4 .   ? 149.030 169.849 183.466 1.00 80.77  ? 2   NAG K C4  1 
HETATM 11858 C C5  . NAG K 4 .   ? 150.490 170.125 183.813 1.00 80.77  ? 2   NAG K C5  1 
HETATM 11859 C C6  . NAG K 4 .   ? 150.812 169.858 185.265 1.00 80.77  ? 2   NAG K C6  1 
HETATM 11860 C C7  . NAG K 4 .   ? 149.791 170.557 179.121 1.00 80.77  ? 2   NAG K C7  1 
HETATM 11861 C C8  . NAG K 4 .   ? 149.560 170.549 177.640 1.00 80.77  ? 2   NAG K C8  1 
HETATM 11862 N N2  . NAG K 4 .   ? 149.621 169.383 179.744 1.00 80.77  ? 2   NAG K N2  1 
HETATM 11863 O O3  . NAG K 4 .   ? 147.474 169.641 181.632 1.00 80.77  ? 2   NAG K O3  1 
HETATM 11864 O O4  . NAG K 4 .   ? 148.198 170.745 184.193 1.00 80.77  ? 2   NAG K O4  1 
HETATM 11865 O O5  . NAG K 4 .   ? 151.346 169.274 183.037 1.00 80.77  ? 2   NAG K O5  1 
HETATM 11866 O O6  . NAG K 4 .   ? 150.691 168.478 185.578 1.00 80.77  ? 2   NAG K O6  1 
HETATM 11867 O O7  . NAG K 4 .   ? 150.118 171.579 179.720 1.00 80.77  ? 2   NAG K O7  1 
HETATM 11868 C C1  . NAG L 4 .   ? 174.732 182.232 179.976 1.00 80.31  ? 1   NAG L C1  1 
HETATM 11869 C C2  . NAG L 4 .   ? 174.681 183.127 181.219 1.00 80.31  ? 1   NAG L C2  1 
HETATM 11870 C C3  . NAG L 4 .   ? 173.842 182.481 182.327 1.00 80.31  ? 1   NAG L C3  1 
HETATM 11871 C C4  . NAG L 4 .   ? 174.277 181.045 182.599 1.00 80.31  ? 1   NAG L C4  1 
HETATM 11872 C C5  . NAG L 4 .   ? 174.499 180.287 181.295 1.00 80.31  ? 1   NAG L C5  1 
HETATM 11873 C C6  . NAG L 4 .   ? 173.795 178.951 181.262 0.10 80.31  ? 1   NAG L C6  1 
HETATM 11874 C C7  . NAG L 4 .   ? 176.626 184.600 181.483 0.10 80.31  ? 1   NAG L C7  1 
HETATM 11875 C C8  . NAG L 4 .   ? 178.006 184.741 182.050 0.10 80.31  ? 1   NAG L C8  1 
HETATM 11876 N N2  . NAG L 4 .   ? 176.019 183.429 181.700 0.10 80.31  ? 1   NAG L N2  1 
HETATM 11877 O O3  . NAG L 4 .   ? 172.469 182.509 181.955 1.00 80.31  ? 1   NAG L O3  1 
HETATM 11878 O O4  . NAG L 4 .   ? 175.480 181.036 183.359 1.00 80.31  ? 1   NAG L O4  1 
HETATM 11879 O O5  . NAG L 4 .   ? 173.979 181.056 180.205 1.00 80.31  ? 1   NAG L O5  1 
HETATM 11880 O O6  . NAG L 4 .   ? 172.399 179.106 181.050 0.10 80.31  ? 1   NAG L O6  1 
HETATM 11881 O O7  . NAG L 4 .   ? 176.085 185.506 180.856 0.10 80.31  ? 1   NAG L O7  1 
HETATM 11882 C C1  . NAG L 4 .   ? 175.150 181.244 184.746 1.00 99.15  ? 2   NAG L C1  1 
HETATM 11883 C C2  . NAG L 4 .   ? 175.665 180.051 185.556 1.00 99.15  ? 2   NAG L C2  1 
HETATM 11884 C C3  . NAG L 4 .   ? 175.396 180.259 187.045 1.00 99.15  ? 2   NAG L C3  1 
HETATM 11885 C C4  . NAG L 4 .   ? 175.953 181.600 187.504 1.00 99.15  ? 2   NAG L C4  1 
HETATM 11886 C C5  . NAG L 4 .   ? 175.421 182.724 186.620 1.00 99.15  ? 2   NAG L C5  1 
HETATM 11887 C C6  . NAG L 4 .   ? 176.025 184.070 186.948 1.00 99.15  ? 2   NAG L C6  1 
HETATM 11888 C C7  . NAG L 4 .   ? 173.777 178.512 185.113 1.00 99.15  ? 2   NAG L C7  1 
HETATM 11889 C C8  . NAG L 4 .   ? 173.395 177.161 184.590 1.00 99.15  ? 2   NAG L C8  1 
HETATM 11890 N N2  . NAG L 4 .   ? 175.087 178.797 185.094 1.00 99.15  ? 2   NAG L N2  1 
HETATM 11891 O O3  . NAG L 4 .   ? 175.994 179.203 187.788 1.00 99.15  ? 2   NAG L O3  1 
HETATM 11892 O O4  . NAG L 4 .   ? 175.576 181.847 188.854 1.00 99.15  ? 2   NAG L O4  1 
HETATM 11893 O O5  . NAG L 4 .   ? 175.736 182.454 185.245 1.00 99.15  ? 2   NAG L O5  1 
HETATM 11894 O O6  . NAG L 4 .   ? 177.434 183.983 187.106 1.00 99.15  ? 2   NAG L O6  1 
HETATM 11895 O O7  . NAG L 4 .   ? 172.938 179.306 185.532 1.00 99.15  ? 2   NAG L O7  1 
HETATM 11896 C C1  . NAG M 4 .   ? 179.515 188.637 168.360 1.00 102.68 ? 1   NAG M C1  1 
HETATM 11897 C C2  . NAG M 4 .   ? 180.982 188.960 168.643 1.00 102.68 ? 1   NAG M C2  1 
HETATM 11898 C C3  . NAG M 4 .   ? 181.357 190.336 168.082 1.00 102.68 ? 1   NAG M C3  1 
HETATM 11899 C C4  . NAG M 4 .   ? 180.283 191.380 168.370 1.00 102.68 ? 1   NAG M C4  1 
HETATM 11900 C C5  . NAG M 4 .   ? 178.896 190.877 167.981 1.00 102.68 ? 1   NAG M C5  1 
HETATM 11901 C C6  . NAG M 4 .   ? 178.227 191.737 166.934 0.10 102.68 ? 1   NAG M C6  1 
HETATM 11902 C C7  . NAG M 4 .   ? 182.418 188.416 170.557 0.10 102.68 ? 1   NAG M C7  1 
HETATM 11903 C C8  . NAG M 4 .   ? 182.546 188.420 172.050 0.10 102.68 ? 1   NAG M C8  1 
HETATM 11904 N N2  . NAG M 4 .   ? 181.269 188.893 170.066 0.10 102.68 ? 1   NAG M N2  1 
HETATM 11905 O O3  . NAG M 4 .   ? 181.568 190.231 166.678 1.00 102.68 ? 1   NAG M O3  1 
HETATM 11906 O O4  . NAG M 4 .   ? 180.285 191.722 169.751 1.00 102.68 ? 1   NAG M O4  1 
HETATM 11907 O O5  . NAG M 4 .   ? 178.998 189.559 167.429 1.00 102.68 ? 1   NAG M O5  1 
HETATM 11908 O O6  . NAG M 4 .   ? 178.238 191.107 165.660 0.10 102.68 ? 1   NAG M O6  1 
HETATM 11909 O O7  . NAG M 4 .   ? 183.313 188.001 169.828 0.10 102.68 ? 1   NAG M O7  1 
HETATM 11910 C C1  . NAG M 4 .   ? 181.341 192.671 169.997 1.00 120.99 ? 2   NAG M C1  1 
HETATM 11911 C C2  . NAG M 4 .   ? 180.723 194.025 170.366 1.00 120.99 ? 2   NAG M C2  1 
HETATM 11912 C C3  . NAG M 4 .   ? 181.816 195.036 170.708 1.00 120.99 ? 2   NAG M C3  1 
HETATM 11913 C C4  . NAG M 4 .   ? 182.747 194.474 171.774 1.00 120.99 ? 2   NAG M C4  1 
HETATM 11914 C C5  . NAG M 4 .   ? 183.284 193.113 171.342 1.00 120.99 ? 2   NAG M C5  1 
HETATM 11915 C C6  . NAG M 4 .   ? 184.125 192.445 172.406 1.00 120.99 ? 2   NAG M C6  1 
HETATM 11916 C C7  . NAG M 4 .   ? 180.274 194.831 168.069 1.00 120.99 ? 2   NAG M C7  1 
HETATM 11917 C C8  . NAG M 4 .   ? 179.218 195.339 167.133 1.00 120.99 ? 2   NAG M C8  1 
HETATM 11918 N N2  . NAG M 4 .   ? 179.860 194.531 169.308 1.00 120.99 ? 2   NAG M N2  1 
HETATM 11919 O O3  . NAG M 4 .   ? 181.219 196.242 171.170 1.00 120.99 ? 2   NAG M O3  1 
HETATM 11920 O O4  . NAG M 4 .   ? 183.839 195.363 171.983 1.00 120.99 ? 2   NAG M O4  1 
HETATM 11921 O O5  . NAG M 4 .   ? 182.193 192.225 171.060 1.00 120.99 ? 2   NAG M O5  1 
HETATM 11922 O O6  . NAG M 4 .   ? 183.636 192.734 173.708 1.00 120.99 ? 2   NAG M O6  1 
HETATM 11923 O O7  . NAG M 4 .   ? 181.442 194.697 167.715 1.00 120.99 ? 2   NAG M O7  1 
HETATM 11924 C C1  . NAG N 4 .   ? 175.848 195.657 132.990 1.00 170.45 ? 1   NAG N C1  1 
HETATM 11925 C C2  . NAG N 4 .   ? 174.670 196.538 132.514 1.00 170.45 ? 1   NAG N C2  1 
HETATM 11926 C C3  . NAG N 4 .   ? 174.221 197.517 133.607 1.00 170.45 ? 1   NAG N C3  1 
HETATM 11927 C C4  . NAG N 4 .   ? 175.375 197.905 134.523 1.00 170.45 ? 1   NAG N C4  1 
HETATM 11928 C C5  . NAG N 4 .   ? 176.683 197.858 133.746 1.00 170.45 ? 1   NAG N C5  1 
HETATM 11929 C C6  . NAG N 4 .   ? 177.863 198.372 134.539 0.10 170.45 ? 1   NAG N C6  1 
HETATM 11930 C C7  . NAG N 4 .   ? 174.052 197.658 130.417 0.10 170.45 ? 1   NAG N C7  1 
HETATM 11931 C C8  . NAG N 4 .   ? 174.557 198.368 129.197 0.10 170.45 ? 1   NAG N C8  1 
HETATM 11932 N N2  . NAG N 4 .   ? 174.985 197.242 131.280 0.10 170.45 ? 1   NAG N N2  1 
HETATM 11933 O O3  . NAG N 4 .   ? 173.179 196.905 134.359 1.00 170.45 ? 1   NAG N O3  1 
HETATM 11934 O O4  . NAG N 4 .   ? 175.205 199.233 135.010 1.00 170.45 ? 1   NAG N O4  1 
HETATM 11935 O O5  . NAG N 4 .   ? 176.983 196.502 133.386 1.00 170.45 ? 1   NAG N O5  1 
HETATM 11936 O O6  . NAG N 4 .   ? 177.582 198.400 135.931 0.10 170.45 ? 1   NAG N O6  1 
HETATM 11937 O O7  . NAG N 4 .   ? 172.856 197.469 130.612 0.10 170.45 ? 1   NAG N O7  1 
HETATM 11938 C C1  . NAG N 4 .   ? 174.125 199.337 135.958 1.00 172.07 ? 2   NAG N C1  1 
HETATM 11939 C C2  . NAG N 4 .   ? 174.612 200.077 137.209 1.00 172.07 ? 2   NAG N C2  1 
HETATM 11940 C C3  . NAG N 4 .   ? 173.459 200.295 138.189 1.00 172.07 ? 2   NAG N C3  1 
HETATM 11941 C C4  . NAG N 4 .   ? 172.285 200.968 137.492 1.00 172.07 ? 2   NAG N C4  1 
HETATM 11942 C C5  . NAG N 4 .   ? 171.888 200.175 136.251 1.00 172.07 ? 2   NAG N C5  1 
HETATM 11943 C C6  . NAG N 4 .   ? 170.797 200.842 135.448 1.00 172.07 ? 2   NAG N C6  1 
HETATM 11944 C C7  . NAG N 4 .   ? 175.627 198.146 138.378 1.00 172.07 ? 2   NAG N C7  1 
HETATM 11945 C C8  . NAG N 4 .   ? 176.882 197.611 139.000 1.00 172.07 ? 2   NAG N C8  1 
HETATM 11946 N N2  . NAG N 4 .   ? 175.714 199.376 137.854 1.00 172.07 ? 2   NAG N N2  1 
HETATM 11947 O O3  . NAG N 4 .   ? 173.906 201.098 139.275 1.00 172.07 ? 2   NAG N O3  1 
HETATM 11948 O O4  . NAG N 4 .   ? 171.172 201.043 138.375 1.00 172.07 ? 2   NAG N O4  1 
HETATM 11949 O O5  . NAG N 4 .   ? 173.021 200.042 135.380 1.00 172.07 ? 2   NAG N O5  1 
HETATM 11950 O O6  . NAG N 4 .   ? 171.032 202.237 135.312 1.00 172.07 ? 2   NAG N O6  1 
HETATM 11951 O O7  . NAG N 4 .   ? 174.588 197.491 138.350 1.00 172.07 ? 2   NAG N O7  1 
HETATM 11952 C C1  . NAG O 5 .   ? 163.067 132.115 149.611 1.00 97.42  ? 701 NAG B C1  1 
HETATM 11953 C C2  . NAG O 5 .   ? 162.954 131.756 151.092 1.00 97.42  ? 701 NAG B C2  1 
HETATM 11954 C C3  . NAG O 5 .   ? 164.319 131.858 151.782 1.00 97.42  ? 701 NAG B C3  1 
HETATM 11955 C C4  . NAG O 5 .   ? 165.079 133.108 151.350 1.00 97.42  ? 701 NAG B C4  1 
HETATM 11956 C C5  . NAG O 5 .   ? 165.136 133.226 149.829 1.00 97.42  ? 701 NAG B C5  1 
HETATM 11957 C C6  . NAG O 5 .   ? 166.545 133.180 149.285 1.00 97.42  ? 701 NAG B C6  1 
HETATM 11958 C C7  . NAG O 5 .   ? 160.801 132.154 152.202 1.00 97.42  ? 701 NAG B C7  1 
HETATM 11959 C C8  . NAG O 5 .   ? 159.919 133.166 152.867 1.00 97.42  ? 701 NAG B C8  1 
HETATM 11960 N N2  . NAG O 5 .   ? 161.980 132.603 151.761 1.00 97.42  ? 701 NAG B N2  1 
HETATM 11961 O O3  . NAG O 5 .   ? 165.086 130.697 151.485 1.00 97.42  ? 701 NAG B O3  1 
HETATM 11962 O O4  . NAG O 5 .   ? 164.449 134.267 151.883 1.00 97.42  ? 701 NAG B O4  1 
HETATM 11963 O O5  . NAG O 5 .   ? 164.427 132.135 149.231 1.00 97.42  ? 701 NAG B O5  1 
HETATM 11964 O O6  . NAG O 5 .   ? 166.580 132.617 147.981 1.00 97.42  ? 701 NAG B O6  1 
HETATM 11965 O O7  . NAG O 5 .   ? 160.461 130.982 152.069 1.00 97.42  ? 701 NAG B O7  1 
HETATM 11966 C C1  . NAG P 5 .   ? 138.761 172.482 142.954 1.00 90.77  ? 702 NAG B C1  1 
HETATM 11967 C C2  . NAG P 5 .   ? 137.926 173.545 143.673 1.00 90.77  ? 702 NAG B C2  1 
HETATM 11968 C C3  . NAG P 5 .   ? 138.742 174.821 143.872 1.00 90.77  ? 702 NAG B C3  1 
HETATM 11969 C C4  . NAG P 5 .   ? 140.061 174.505 144.564 1.00 90.77  ? 702 NAG B C4  1 
HETATM 11970 C C5  . NAG P 5 .   ? 140.807 173.410 143.807 1.00 90.77  ? 702 NAG B C5  1 
HETATM 11971 C C6  . NAG P 5 .   ? 142.072 172.966 144.505 1.00 90.77  ? 702 NAG B C6  1 
HETATM 11972 C C7  . NAG P 5 .   ? 136.616 174.311 141.718 1.00 90.77  ? 702 NAG B C7  1 
HETATM 11973 C C8  . NAG P 5 .   ? 135.235 174.527 141.178 1.00 90.77  ? 702 NAG B C8  1 
HETATM 11974 N N2  . NAG P 5 .   ? 136.685 173.825 142.965 1.00 90.77  ? 702 NAG B N2  1 
HETATM 11975 O O3  . NAG P 5 .   ? 137.992 175.746 144.649 1.00 90.77  ? 702 NAG B O3  1 
HETATM 11976 O O4  . NAG P 5 .   ? 140.873 175.673 144.621 1.00 90.77  ? 702 NAG B O4  1 
HETATM 11977 O O5  . NAG P 5 .   ? 139.974 172.249 143.681 1.00 90.77  ? 702 NAG B O5  1 
HETATM 11978 O O6  . NAG P 5 .   ? 142.801 172.036 143.716 1.00 90.77  ? 702 NAG B O6  1 
HETATM 11979 O O7  . NAG P 5 .   ? 137.618 174.566 141.055 1.00 90.77  ? 702 NAG B O7  1 
HETATM 11980 C C1  . NAG Q 5 .   ? 199.121 90.449  117.437 1.00 225.90 ? 703 NAG B C1  1 
HETATM 11981 C C2  . NAG Q 5 .   ? 200.083 91.638  117.525 1.00 225.90 ? 703 NAG B C2  1 
HETATM 11982 C C3  . NAG Q 5 .   ? 201.539 91.164  117.476 1.00 225.90 ? 703 NAG B C3  1 
HETATM 11983 C C4  . NAG Q 5 .   ? 201.768 90.157  116.353 1.00 225.90 ? 703 NAG B C4  1 
HETATM 11984 C C5  . NAG Q 5 .   ? 200.712 89.057  116.375 1.00 225.90 ? 703 NAG B C5  1 
HETATM 11985 C C6  . NAG Q 5 .   ? 201.305 87.673  116.505 0.00 225.90 ? 703 NAG B C6  1 
HETATM 11986 C C7  . NAG Q 5 .   ? 200.174 93.884  116.534 0.00 225.90 ? 703 NAG B C7  1 
HETATM 11987 C C8  . NAG Q 5 .   ? 199.828 94.726  115.343 0.00 225.90 ? 703 NAG B C8  1 
HETATM 11988 N N2  . NAG Q 5 .   ? 199.824 92.595  116.462 1.00 225.90 ? 703 NAG B N2  1 
HETATM 11989 O O3  . NAG Q 5 .   ? 201.885 90.581  118.728 1.00 225.90 ? 703 NAG B O3  1 
HETATM 11990 O O4  . NAG Q 5 .   ? 201.725 90.818  115.092 0.50 225.90 ? 703 NAG B O4  1 
HETATM 11991 O O5  . NAG Q 5 .   ? 199.850 89.241  117.503 1.00 225.90 ? 703 NAG B O5  1 
HETATM 11992 O O6  . NAG Q 5 .   ? 202.353 87.464  115.567 0.00 225.90 ? 703 NAG B O6  1 
HETATM 11993 O O7  . NAG Q 5 .   ? 200.741 94.349  117.517 0.00 225.90 ? 703 NAG B O7  1 
HETATM 11994 C C1  . NAG R 5 .   ? 160.113 168.986 204.483 1.00 100.86 ? 801 NAG C C1  1 
HETATM 11995 C C2  . NAG R 5 .   ? 161.103 170.007 203.925 1.00 100.86 ? 801 NAG C C2  1 
HETATM 11996 C C3  . NAG R 5 .   ? 160.448 170.860 202.835 1.00 100.86 ? 801 NAG C C3  1 
HETATM 11997 C C4  . NAG R 5 .   ? 159.032 171.275 203.218 1.00 100.86 ? 801 NAG C C4  1 
HETATM 11998 C C5  . NAG R 5 .   ? 158.194 170.071 203.642 1.00 100.86 ? 801 NAG C C5  1 
HETATM 11999 C C6  . NAG R 5 .   ? 157.021 169.816 202.725 0.10 100.86 ? 801 NAG C C6  1 
HETATM 12000 C C7  . NAG R 5 .   ? 162.887 170.750 205.438 0.10 100.86 ? 801 NAG C C7  1 
HETATM 12001 C C8  . NAG R 5 .   ? 163.267 171.700 206.534 0.10 100.86 ? 801 NAG C C8  1 
HETATM 12002 N N2  . NAG R 5 .   ? 161.634 170.851 204.984 0.10 100.86 ? 801 NAG C N2  1 
HETATM 12003 O O3  . NAG R 5 .   ? 160.425 170.127 201.615 1.00 100.86 ? 801 NAG C O3  1 
HETATM 12004 O O4  . NAG R 5 .   ? 159.074 172.213 204.287 1.00 100.86 ? 801 NAG C O4  1 
HETATM 12005 O O5  . NAG R 5 .   ? 158.999 168.887 203.620 1.00 100.86 ? 801 NAG C O5  1 
HETATM 12006 O O6  . NAG R 5 .   ? 157.320 168.810 201.767 0.10 100.86 ? 801 NAG C O6  1 
HETATM 12007 O O7  . NAG R 5 .   ? 163.679 169.929 204.986 0.10 100.86 ? 801 NAG C O7  1 
HETATM 12008 C C1  . NAG S 5 .   ? 166.004 165.277 232.939 1.00 168.04 ? 802 NAG C C1  1 
HETATM 12009 C C2  . NAG S 5 .   ? 165.554 164.227 233.957 1.00 168.04 ? 802 NAG C C2  1 
HETATM 12010 C C3  . NAG S 5 .   ? 166.735 163.760 234.814 1.00 168.04 ? 802 NAG C C3  1 
HETATM 12011 C C4  . NAG S 5 .   ? 167.579 164.935 235.298 1.00 168.04 ? 802 NAG C C4  1 
HETATM 12012 C C5  . NAG S 5 .   ? 167.942 165.867 234.146 1.00 168.04 ? 802 NAG C C5  1 
HETATM 12013 C C6  . NAG S 5 .   ? 169.433 166.013 233.950 0.10 168.04 ? 802 NAG C C6  1 
HETATM 12014 C C7  . NAG S 5 .   ? 163.246 164.237 234.791 0.10 168.04 ? 802 NAG C C7  1 
HETATM 12015 C C8  . NAG S 5 .   ? 162.267 164.888 235.721 0.10 168.04 ? 802 NAG C C8  1 
HETATM 12016 N N2  . NAG S 5 .   ? 164.484 164.740 234.797 0.10 168.04 ? 802 NAG C N2  1 
HETATM 12017 O O3  . NAG S 5 .   ? 167.540 162.862 234.060 1.00 168.04 ? 802 NAG C O3  1 
HETATM 12018 O O4  . NAG S 5 .   ? 166.867 165.670 236.287 1.00 168.04 ? 802 NAG C O4  1 
HETATM 12019 O O5  . NAG S 5 .   ? 167.414 165.347 232.920 1.00 168.04 ? 802 NAG C O5  1 
HETATM 12020 O O6  . NAG S 5 .   ? 169.806 165.770 232.601 0.10 168.04 ? 802 NAG C O6  1 
HETATM 12021 O O7  . NAG S 5 .   ? 162.929 163.298 234.066 0.10 168.04 ? 802 NAG C O7  1 
HETATM 12022 C C1  . NAG T 5 .   ? 177.679 165.767 165.614 1.00 79.87  ? 803 NAG C C1  1 
HETATM 12023 C C2  . NAG T 5 .   ? 178.289 164.742 166.567 1.00 79.87  ? 803 NAG C C2  1 
HETATM 12024 C C3  . NAG T 5 .   ? 177.599 163.383 166.411 1.00 79.87  ? 803 NAG C C3  1 
HETATM 12025 C C4  . NAG T 5 .   ? 177.087 163.158 164.990 1.00 79.87  ? 803 NAG C C4  1 
HETATM 12026 C C5  . NAG T 5 .   ? 176.205 164.309 164.502 1.00 79.87  ? 803 NAG C C5  1 
HETATM 12027 C C6  . NAG T 5 .   ? 174.738 163.952 164.452 0.10 79.87  ? 803 NAG C C6  1 
HETATM 12028 C C7  . NAG T 5 .   ? 180.569 164.227 167.313 0.10 79.87  ? 803 NAG C C7  1 
HETATM 12029 C C8  . NAG T 5 .   ? 182.014 164.153 166.921 0.10 79.87  ? 803 NAG C C8  1 
HETATM 12030 N N2  . NAG T 5 .   ? 179.722 164.617 166.355 0.10 79.87  ? 803 NAG C N2  1 
HETATM 12031 O O3  . NAG T 5 .   ? 176.522 163.291 167.336 1.00 79.87  ? 803 NAG C O3  1 
HETATM 12032 O O4  . NAG T 5 .   ? 178.183 162.991 164.097 1.00 79.87  ? 803 NAG C O4  1 
HETATM 12033 O O5  . NAG T 5 .   ? 176.327 165.441 165.373 1.00 79.87  ? 803 NAG C O5  1 
HETATM 12034 O O6  . NAG T 5 .   ? 174.225 164.052 163.131 0.10 79.87  ? 803 NAG C O6  1 
HETATM 12035 O O7  . NAG T 5 .   ? 180.186 163.948 168.445 0.10 79.87  ? 803 NAG C O7  1 
HETATM 12036 C C1  . NAG U 5 .   ? 188.598 184.095 146.062 1.00 110.94 ? 804 NAG C C1  1 
HETATM 12037 C C2  . NAG U 5 .   ? 189.390 183.301 145.019 1.00 110.94 ? 804 NAG C C2  1 
HETATM 12038 C C3  . NAG U 5 .   ? 190.776 182.930 145.554 1.00 110.94 ? 804 NAG C C3  1 
HETATM 12039 C C4  . NAG U 5 .   ? 190.688 182.269 146.925 1.00 110.94 ? 804 NAG C C4  1 
HETATM 12040 C C5  . NAG U 5 .   ? 189.746 183.042 147.841 1.00 110.94 ? 804 NAG C C5  1 
HETATM 12041 C C6  . NAG U 5 .   ? 190.367 183.384 149.175 0.10 110.94 ? 804 NAG C C6  1 
HETATM 12042 C C7  . NAG U 5 .   ? 188.848 181.508 143.432 0.10 110.94 ? 804 NAG C C7  1 
HETATM 12043 C C8  . NAG U 5 .   ? 188.013 180.289 143.179 0.10 110.94 ? 804 NAG C C8  1 
HETATM 12044 N N2  . NAG U 5 .   ? 188.664 182.109 144.612 0.10 110.94 ? 804 NAG C N2  1 
HETATM 12045 O O3  . NAG U 5 .   ? 191.580 184.102 145.632 1.00 110.94 ? 804 NAG C O3  1 
HETATM 12046 O O4  . NAG U 5 .   ? 190.214 180.934 146.790 1.00 110.94 ? 804 NAG C O4  1 
HETATM 12047 O O5  . NAG U 5 .   ? 189.390 184.283 147.220 1.00 110.94 ? 804 NAG C O5  1 
HETATM 12048 O O6  . NAG U 5 .   ? 190.904 184.700 149.176 0.10 110.94 ? 804 NAG C O6  1 
HETATM 12049 O O7  . NAG U 5 .   ? 189.650 181.930 142.605 0.10 110.94 ? 804 NAG C O7  1 
# 
