data_8V29
# 
_entry.id   8V29 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.399 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8V29         pdb_00008v29 10.2210/pdb8v29/pdb 
WWPDB D_1000278759 ?            ?                   
EMDB  EMD-42902    ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2024-11-20 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8V29 
_pdbx_database_status.recvd_initial_deposition_date   2023-11-22 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        
'Cryo-EM structure of human type I OSM receptor complex: model for full extracellular assembly' 
_pdbx_database_related.db_id          EMD-42902 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              matthew.franklin@regeneron.com 
_pdbx_contact_author.name_first         Matthew 
_pdbx_contact_author.name_last          Franklin 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-1482-0136 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Zhou, Y.'       1 ? 
'Franklin, M.C.' 2 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Nat Commun' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2041-1723 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            15 
_citation.language                  ? 
_citation.page_first                9776 
_citation.page_last                 9776 
_citation.title                     
'Structures of complete extracellular assemblies of type I and type II Oncostatin M receptor complexes.' 
_citation.year                      2024 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1038/s41467-024-54124-1 
_citation.pdbx_database_id_PubMed   39532904 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Zhou, Y.'       1 0000-0002-1650-4591 
primary 'Stevis, P.E.'   2 ?                   
primary 'Cao, J.'        3 ?                   
primary 'Ehrlich, G.'    4 ?                   
primary 'Jones, J.'      5 ?                   
primary 'Rafique, A.'    6 0000-0003-4078-7242 
primary 'Sleeman, M.W.'  7 ?                   
primary 'Olson, W.C.'    8 ?                   
primary 'Franklin, M.C.' 9 0000-0002-1482-0136 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man Oncostatin-M                                                                              22186.369 1 ? ? ? ? 
2 polymer     man 'Interleukin-6 receptor subunit beta'                                                     71233.203 1 ? ? ? ? 
3 polymer     man 'Leukemia inhibitory factor receptor'                                                     92834.812 1 ? ? ? ? 
4 branched    man '2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose' 424.401   5 ? ? ? ? 
5 non-polymer man 2-acetamido-2-deoxy-beta-D-glucopyranose                                                  221.208   9 ? ? ? ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
2 
;IL-6 receptor subunit beta,IL-6R subunit beta,IL-6R-beta,IL-6RB,CDw130,Interleukin-6 signal transducer,Membrane glycoprotein 130,gp130,Oncostatin-M receptor subunit alpha
;
3 'LIF receptor,LIF-R' 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;AAIGSCSKEYRVLLGQLQKQTDLMQDTSRLLDPYIRIQGLDVPKLREHCRERPGAFPSEETLRGLGRRGFLQTLNATLGC
VLHRLADLEQRLPKAQDLERSGLNIEDLEKLQMARPNILGLRNNIYCMAQLLDNSDTAEPTKAGRGASQPPTPTPASDAF
QRKLEGCRFLHGYHRFMHSVGRVFSKWGESPNRSRR
;
;AAIGSCSKEYRVLLGQLQKQTDLMQDTSRLLDPYIRIQGLDVPKLREHCRERPGAFPSEETLRGLGRRGFLQTLNATLGC
VLHRLADLEQRLPKAQDLERSGLNIEDLEKLQMARPNILGLRNNIYCMAQLLDNSDTAEPTKAGRGASQPPTPTPASDAF
QRKLEGCRFLHGYHRFMHSVGRVFSKWGESPNRSRR
;
A ? 
2 'polypeptide(L)' no no 
;ELLDPCGYISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLT
CNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSC
TVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYR
TKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQ
GYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQ
ATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYAD
GPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSL
TSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEEQKLISEEDLGGEQKLISEEDLHHHHHH
;
;ELLDPCGYISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLT
CNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSC
TVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYR
TKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQ
GYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQ
ATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYAD
GPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSL
TSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEEQKLISEEDLGGEQKLISEEDLHHHHHH
;
B ? 
3 'polypeptide(L)' no no 
;QKKGAPHDLKCVTNNLQVWNCSWKAPSGTGRGTDYEVCIENRSRSCYQLEKTSIKIPALSHGDYEITINSLHDFGSSTSK
FTLNEQNVSLIPDTPEILNLSADFSTSTLYLKWNDRGSVFPHRSNVIWEIKVLRKESMELVKLVTHNTTLNGKDTLHHWS
WASDMPLECAIHFVEIRCYIDNLHFSGLEEWSDWSPVKNISWIPDSQTKVFPQDKVILVGSDITFCCVSQEKVLSALIGH
TNCPLIHLDGENVAIKIRNISVSASSGTNVVFTTEDNIFGTVIFAGYPPDTPQQLNCETHDLKEIICSWNPGRVTALVGP
RATSYTLVESFSGKYVRLKRAEAPTNESYQLLFQMLPNQEIYNFTLNAHNPLGRSQSTILVNITEKVYPHTPTSFKVKDI
NSTAVKLSWHLPGNFAKINFLCEIEIKKSNSVQEQRNVTIKGVENSSYLVALDKLNPYTLYTFRIRCSTETFWKWSKWSN
KKQHLTTEASPSKGPDTWREWSSDGKNLIIYWKPLPINEANGKILSYNVSCSSDEETQSLSEIPDPQHKAEIRLDKNDYI
ISVVAKNSVGSSPPSKIASMEIPNDDLKIEQVVGMGKGILLTWHYDPNMTCDYVIKWCNSSRSEPCLMDWRKVPSNSTET
VIESDEFRPGIRYNFFLYGCRNQGYQLLRSMIGYIEELAPIVAPNFTVEDTSADSILVKWEDIPVEELRGFLRGYLFYFG
KGERDTSKMRVLESGRSDIKVKNITDISQKTLRIADLQGKTSYHLVLRAYTDGGVGPEKSMYVVTKENSEQKLISEEDLG
GEQKLISEEDLHHHHHH
;
;QKKGAPHDLKCVTNNLQVWNCSWKAPSGTGRGTDYEVCIENRSRSCYQLEKTSIKIPALSHGDYEITINSLHDFGSSTSK
FTLNEQNVSLIPDTPEILNLSADFSTSTLYLKWNDRGSVFPHRSNVIWEIKVLRKESMELVKLVTHNTTLNGKDTLHHWS
WASDMPLECAIHFVEIRCYIDNLHFSGLEEWSDWSPVKNISWIPDSQTKVFPQDKVILVGSDITFCCVSQEKVLSALIGH
TNCPLIHLDGENVAIKIRNISVSASSGTNVVFTTEDNIFGTVIFAGYPPDTPQQLNCETHDLKEIICSWNPGRVTALVGP
RATSYTLVESFSGKYVRLKRAEAPTNESYQLLFQMLPNQEIYNFTLNAHNPLGRSQSTILVNITEKVYPHTPTSFKVKDI
NSTAVKLSWHLPGNFAKINFLCEIEIKKSNSVQEQRNVTIKGVENSSYLVALDKLNPYTLYTFRIRCSTETFWKWSKWSN
KKQHLTTEASPSKGPDTWREWSSDGKNLIIYWKPLPINEANGKILSYNVSCSSDEETQSLSEIPDPQHKAEIRLDKNDYI
ISVVAKNSVGSSPPSKIASMEIPNDDLKIEQVVGMGKGILLTWHYDPNMTCDYVIKWCNSSRSEPCLMDWRKVPSNSTET
VIESDEFRPGIRYNFFLYGCRNQGYQLLRSMIGYIEELAPIVAPNFTVEDTSADSILVKWEDIPVEELRGFLRGYLFYFG
KGERDTSKMRVLESGRSDIKVKNITDISQKTLRIADLQGKTSYHLVLRAYTDGGVGPEKSMYVVTKENSEQKLISEEDLG
GEQKLISEEDLHHHHHH
;
C ? 
# 
_pdbx_entity_nonpoly.entity_id   5 
_pdbx_entity_nonpoly.name        2-acetamido-2-deoxy-beta-D-glucopyranose 
_pdbx_entity_nonpoly.comp_id     NAG 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   ALA n 
1 2   ALA n 
1 3   ILE n 
1 4   GLY n 
1 5   SER n 
1 6   CYS n 
1 7   SER n 
1 8   LYS n 
1 9   GLU n 
1 10  TYR n 
1 11  ARG n 
1 12  VAL n 
1 13  LEU n 
1 14  LEU n 
1 15  GLY n 
1 16  GLN n 
1 17  LEU n 
1 18  GLN n 
1 19  LYS n 
1 20  GLN n 
1 21  THR n 
1 22  ASP n 
1 23  LEU n 
1 24  MET n 
1 25  GLN n 
1 26  ASP n 
1 27  THR n 
1 28  SER n 
1 29  ARG n 
1 30  LEU n 
1 31  LEU n 
1 32  ASP n 
1 33  PRO n 
1 34  TYR n 
1 35  ILE n 
1 36  ARG n 
1 37  ILE n 
1 38  GLN n 
1 39  GLY n 
1 40  LEU n 
1 41  ASP n 
1 42  VAL n 
1 43  PRO n 
1 44  LYS n 
1 45  LEU n 
1 46  ARG n 
1 47  GLU n 
1 48  HIS n 
1 49  CYS n 
1 50  ARG n 
1 51  GLU n 
1 52  ARG n 
1 53  PRO n 
1 54  GLY n 
1 55  ALA n 
1 56  PHE n 
1 57  PRO n 
1 58  SER n 
1 59  GLU n 
1 60  GLU n 
1 61  THR n 
1 62  LEU n 
1 63  ARG n 
1 64  GLY n 
1 65  LEU n 
1 66  GLY n 
1 67  ARG n 
1 68  ARG n 
1 69  GLY n 
1 70  PHE n 
1 71  LEU n 
1 72  GLN n 
1 73  THR n 
1 74  LEU n 
1 75  ASN n 
1 76  ALA n 
1 77  THR n 
1 78  LEU n 
1 79  GLY n 
1 80  CYS n 
1 81  VAL n 
1 82  LEU n 
1 83  HIS n 
1 84  ARG n 
1 85  LEU n 
1 86  ALA n 
1 87  ASP n 
1 88  LEU n 
1 89  GLU n 
1 90  GLN n 
1 91  ARG n 
1 92  LEU n 
1 93  PRO n 
1 94  LYS n 
1 95  ALA n 
1 96  GLN n 
1 97  ASP n 
1 98  LEU n 
1 99  GLU n 
1 100 ARG n 
1 101 SER n 
1 102 GLY n 
1 103 LEU n 
1 104 ASN n 
1 105 ILE n 
1 106 GLU n 
1 107 ASP n 
1 108 LEU n 
1 109 GLU n 
1 110 LYS n 
1 111 LEU n 
1 112 GLN n 
1 113 MET n 
1 114 ALA n 
1 115 ARG n 
1 116 PRO n 
1 117 ASN n 
1 118 ILE n 
1 119 LEU n 
1 120 GLY n 
1 121 LEU n 
1 122 ARG n 
1 123 ASN n 
1 124 ASN n 
1 125 ILE n 
1 126 TYR n 
1 127 CYS n 
1 128 MET n 
1 129 ALA n 
1 130 GLN n 
1 131 LEU n 
1 132 LEU n 
1 133 ASP n 
1 134 ASN n 
1 135 SER n 
1 136 ASP n 
1 137 THR n 
1 138 ALA n 
1 139 GLU n 
1 140 PRO n 
1 141 THR n 
1 142 LYS n 
1 143 ALA n 
1 144 GLY n 
1 145 ARG n 
1 146 GLY n 
1 147 ALA n 
1 148 SER n 
1 149 GLN n 
1 150 PRO n 
1 151 PRO n 
1 152 THR n 
1 153 PRO n 
1 154 THR n 
1 155 PRO n 
1 156 ALA n 
1 157 SER n 
1 158 ASP n 
1 159 ALA n 
1 160 PHE n 
1 161 GLN n 
1 162 ARG n 
1 163 LYS n 
1 164 LEU n 
1 165 GLU n 
1 166 GLY n 
1 167 CYS n 
1 168 ARG n 
1 169 PHE n 
1 170 LEU n 
1 171 HIS n 
1 172 GLY n 
1 173 TYR n 
1 174 HIS n 
1 175 ARG n 
1 176 PHE n 
1 177 MET n 
1 178 HIS n 
1 179 SER n 
1 180 VAL n 
1 181 GLY n 
1 182 ARG n 
1 183 VAL n 
1 184 PHE n 
1 185 SER n 
1 186 LYS n 
1 187 TRP n 
1 188 GLY n 
1 189 GLU n 
1 190 SER n 
1 191 PRO n 
1 192 ASN n 
1 193 ARG n 
1 194 SER n 
1 195 ARG n 
1 196 ARG n 
2 1   GLU n 
2 2   LEU n 
2 3   LEU n 
2 4   ASP n 
2 5   PRO n 
2 6   CYS n 
2 7   GLY n 
2 8   TYR n 
2 9   ILE n 
2 10  SER n 
2 11  PRO n 
2 12  GLU n 
2 13  SER n 
2 14  PRO n 
2 15  VAL n 
2 16  VAL n 
2 17  GLN n 
2 18  LEU n 
2 19  HIS n 
2 20  SER n 
2 21  ASN n 
2 22  PHE n 
2 23  THR n 
2 24  ALA n 
2 25  VAL n 
2 26  CYS n 
2 27  VAL n 
2 28  LEU n 
2 29  LYS n 
2 30  GLU n 
2 31  LYS n 
2 32  CYS n 
2 33  MET n 
2 34  ASP n 
2 35  TYR n 
2 36  PHE n 
2 37  HIS n 
2 38  VAL n 
2 39  ASN n 
2 40  ALA n 
2 41  ASN n 
2 42  TYR n 
2 43  ILE n 
2 44  VAL n 
2 45  TRP n 
2 46  LYS n 
2 47  THR n 
2 48  ASN n 
2 49  HIS n 
2 50  PHE n 
2 51  THR n 
2 52  ILE n 
2 53  PRO n 
2 54  LYS n 
2 55  GLU n 
2 56  GLN n 
2 57  TYR n 
2 58  THR n 
2 59  ILE n 
2 60  ILE n 
2 61  ASN n 
2 62  ARG n 
2 63  THR n 
2 64  ALA n 
2 65  SER n 
2 66  SER n 
2 67  VAL n 
2 68  THR n 
2 69  PHE n 
2 70  THR n 
2 71  ASP n 
2 72  ILE n 
2 73  ALA n 
2 74  SER n 
2 75  LEU n 
2 76  ASN n 
2 77  ILE n 
2 78  GLN n 
2 79  LEU n 
2 80  THR n 
2 81  CYS n 
2 82  ASN n 
2 83  ILE n 
2 84  LEU n 
2 85  THR n 
2 86  PHE n 
2 87  GLY n 
2 88  GLN n 
2 89  LEU n 
2 90  GLU n 
2 91  GLN n 
2 92  ASN n 
2 93  VAL n 
2 94  TYR n 
2 95  GLY n 
2 96  ILE n 
2 97  THR n 
2 98  ILE n 
2 99  ILE n 
2 100 SER n 
2 101 GLY n 
2 102 LEU n 
2 103 PRO n 
2 104 PRO n 
2 105 GLU n 
2 106 LYS n 
2 107 PRO n 
2 108 LYS n 
2 109 ASN n 
2 110 LEU n 
2 111 SER n 
2 112 CYS n 
2 113 ILE n 
2 114 VAL n 
2 115 ASN n 
2 116 GLU n 
2 117 GLY n 
2 118 LYS n 
2 119 LYS n 
2 120 MET n 
2 121 ARG n 
2 122 CYS n 
2 123 GLU n 
2 124 TRP n 
2 125 ASP n 
2 126 GLY n 
2 127 GLY n 
2 128 ARG n 
2 129 GLU n 
2 130 THR n 
2 131 HIS n 
2 132 LEU n 
2 133 GLU n 
2 134 THR n 
2 135 ASN n 
2 136 PHE n 
2 137 THR n 
2 138 LEU n 
2 139 LYS n 
2 140 SER n 
2 141 GLU n 
2 142 TRP n 
2 143 ALA n 
2 144 THR n 
2 145 HIS n 
2 146 LYS n 
2 147 PHE n 
2 148 ALA n 
2 149 ASP n 
2 150 CYS n 
2 151 LYS n 
2 152 ALA n 
2 153 LYS n 
2 154 ARG n 
2 155 ASP n 
2 156 THR n 
2 157 PRO n 
2 158 THR n 
2 159 SER n 
2 160 CYS n 
2 161 THR n 
2 162 VAL n 
2 163 ASP n 
2 164 TYR n 
2 165 SER n 
2 166 THR n 
2 167 VAL n 
2 168 TYR n 
2 169 PHE n 
2 170 VAL n 
2 171 ASN n 
2 172 ILE n 
2 173 GLU n 
2 174 VAL n 
2 175 TRP n 
2 176 VAL n 
2 177 GLU n 
2 178 ALA n 
2 179 GLU n 
2 180 ASN n 
2 181 ALA n 
2 182 LEU n 
2 183 GLY n 
2 184 LYS n 
2 185 VAL n 
2 186 THR n 
2 187 SER n 
2 188 ASP n 
2 189 HIS n 
2 190 ILE n 
2 191 ASN n 
2 192 PHE n 
2 193 ASP n 
2 194 PRO n 
2 195 VAL n 
2 196 TYR n 
2 197 LYS n 
2 198 VAL n 
2 199 LYS n 
2 200 PRO n 
2 201 ASN n 
2 202 PRO n 
2 203 PRO n 
2 204 HIS n 
2 205 ASN n 
2 206 LEU n 
2 207 SER n 
2 208 VAL n 
2 209 ILE n 
2 210 ASN n 
2 211 SER n 
2 212 GLU n 
2 213 GLU n 
2 214 LEU n 
2 215 SER n 
2 216 SER n 
2 217 ILE n 
2 218 LEU n 
2 219 LYS n 
2 220 LEU n 
2 221 THR n 
2 222 TRP n 
2 223 THR n 
2 224 ASN n 
2 225 PRO n 
2 226 SER n 
2 227 ILE n 
2 228 LYS n 
2 229 SER n 
2 230 VAL n 
2 231 ILE n 
2 232 ILE n 
2 233 LEU n 
2 234 LYS n 
2 235 TYR n 
2 236 ASN n 
2 237 ILE n 
2 238 GLN n 
2 239 TYR n 
2 240 ARG n 
2 241 THR n 
2 242 LYS n 
2 243 ASP n 
2 244 ALA n 
2 245 SER n 
2 246 THR n 
2 247 TRP n 
2 248 SER n 
2 249 GLN n 
2 250 ILE n 
2 251 PRO n 
2 252 PRO n 
2 253 GLU n 
2 254 ASP n 
2 255 THR n 
2 256 ALA n 
2 257 SER n 
2 258 THR n 
2 259 ARG n 
2 260 SER n 
2 261 SER n 
2 262 PHE n 
2 263 THR n 
2 264 VAL n 
2 265 GLN n 
2 266 ASP n 
2 267 LEU n 
2 268 LYS n 
2 269 PRO n 
2 270 PHE n 
2 271 THR n 
2 272 GLU n 
2 273 TYR n 
2 274 VAL n 
2 275 PHE n 
2 276 ARG n 
2 277 ILE n 
2 278 ARG n 
2 279 CYS n 
2 280 MET n 
2 281 LYS n 
2 282 GLU n 
2 283 ASP n 
2 284 GLY n 
2 285 LYS n 
2 286 GLY n 
2 287 TYR n 
2 288 TRP n 
2 289 SER n 
2 290 ASP n 
2 291 TRP n 
2 292 SER n 
2 293 GLU n 
2 294 GLU n 
2 295 ALA n 
2 296 SER n 
2 297 GLY n 
2 298 ILE n 
2 299 THR n 
2 300 TYR n 
2 301 GLU n 
2 302 ASP n 
2 303 ARG n 
2 304 PRO n 
2 305 SER n 
2 306 LYS n 
2 307 ALA n 
2 308 PRO n 
2 309 SER n 
2 310 PHE n 
2 311 TRP n 
2 312 TYR n 
2 313 LYS n 
2 314 ILE n 
2 315 ASP n 
2 316 PRO n 
2 317 SER n 
2 318 HIS n 
2 319 THR n 
2 320 GLN n 
2 321 GLY n 
2 322 TYR n 
2 323 ARG n 
2 324 THR n 
2 325 VAL n 
2 326 GLN n 
2 327 LEU n 
2 328 VAL n 
2 329 TRP n 
2 330 LYS n 
2 331 THR n 
2 332 LEU n 
2 333 PRO n 
2 334 PRO n 
2 335 PHE n 
2 336 GLU n 
2 337 ALA n 
2 338 ASN n 
2 339 GLY n 
2 340 LYS n 
2 341 ILE n 
2 342 LEU n 
2 343 ASP n 
2 344 TYR n 
2 345 GLU n 
2 346 VAL n 
2 347 THR n 
2 348 LEU n 
2 349 THR n 
2 350 ARG n 
2 351 TRP n 
2 352 LYS n 
2 353 SER n 
2 354 HIS n 
2 355 LEU n 
2 356 GLN n 
2 357 ASN n 
2 358 TYR n 
2 359 THR n 
2 360 VAL n 
2 361 ASN n 
2 362 ALA n 
2 363 THR n 
2 364 LYS n 
2 365 LEU n 
2 366 THR n 
2 367 VAL n 
2 368 ASN n 
2 369 LEU n 
2 370 THR n 
2 371 ASN n 
2 372 ASP n 
2 373 ARG n 
2 374 TYR n 
2 375 LEU n 
2 376 ALA n 
2 377 THR n 
2 378 LEU n 
2 379 THR n 
2 380 VAL n 
2 381 ARG n 
2 382 ASN n 
2 383 LEU n 
2 384 VAL n 
2 385 GLY n 
2 386 LYS n 
2 387 SER n 
2 388 ASP n 
2 389 ALA n 
2 390 ALA n 
2 391 VAL n 
2 392 LEU n 
2 393 THR n 
2 394 ILE n 
2 395 PRO n 
2 396 ALA n 
2 397 CYS n 
2 398 ASP n 
2 399 PHE n 
2 400 GLN n 
2 401 ALA n 
2 402 THR n 
2 403 HIS n 
2 404 PRO n 
2 405 VAL n 
2 406 MET n 
2 407 ASP n 
2 408 LEU n 
2 409 LYS n 
2 410 ALA n 
2 411 PHE n 
2 412 PRO n 
2 413 LYS n 
2 414 ASP n 
2 415 ASN n 
2 416 MET n 
2 417 LEU n 
2 418 TRP n 
2 419 VAL n 
2 420 GLU n 
2 421 TRP n 
2 422 THR n 
2 423 THR n 
2 424 PRO n 
2 425 ARG n 
2 426 GLU n 
2 427 SER n 
2 428 VAL n 
2 429 LYS n 
2 430 LYS n 
2 431 TYR n 
2 432 ILE n 
2 433 LEU n 
2 434 GLU n 
2 435 TRP n 
2 436 CYS n 
2 437 VAL n 
2 438 LEU n 
2 439 SER n 
2 440 ASP n 
2 441 LYS n 
2 442 ALA n 
2 443 PRO n 
2 444 CYS n 
2 445 ILE n 
2 446 THR n 
2 447 ASP n 
2 448 TRP n 
2 449 GLN n 
2 450 GLN n 
2 451 GLU n 
2 452 ASP n 
2 453 GLY n 
2 454 THR n 
2 455 VAL n 
2 456 HIS n 
2 457 ARG n 
2 458 THR n 
2 459 TYR n 
2 460 LEU n 
2 461 ARG n 
2 462 GLY n 
2 463 ASN n 
2 464 LEU n 
2 465 ALA n 
2 466 GLU n 
2 467 SER n 
2 468 LYS n 
2 469 CYS n 
2 470 TYR n 
2 471 LEU n 
2 472 ILE n 
2 473 THR n 
2 474 VAL n 
2 475 THR n 
2 476 PRO n 
2 477 VAL n 
2 478 TYR n 
2 479 ALA n 
2 480 ASP n 
2 481 GLY n 
2 482 PRO n 
2 483 GLY n 
2 484 SER n 
2 485 PRO n 
2 486 GLU n 
2 487 SER n 
2 488 ILE n 
2 489 LYS n 
2 490 ALA n 
2 491 TYR n 
2 492 LEU n 
2 493 LYS n 
2 494 GLN n 
2 495 ALA n 
2 496 PRO n 
2 497 PRO n 
2 498 SER n 
2 499 LYS n 
2 500 GLY n 
2 501 PRO n 
2 502 THR n 
2 503 VAL n 
2 504 ARG n 
2 505 THR n 
2 506 LYS n 
2 507 LYS n 
2 508 VAL n 
2 509 GLY n 
2 510 LYS n 
2 511 ASN n 
2 512 GLU n 
2 513 ALA n 
2 514 VAL n 
2 515 LEU n 
2 516 GLU n 
2 517 TRP n 
2 518 ASP n 
2 519 GLN n 
2 520 LEU n 
2 521 PRO n 
2 522 VAL n 
2 523 ASP n 
2 524 VAL n 
2 525 GLN n 
2 526 ASN n 
2 527 GLY n 
2 528 PHE n 
2 529 ILE n 
2 530 ARG n 
2 531 ASN n 
2 532 TYR n 
2 533 THR n 
2 534 ILE n 
2 535 PHE n 
2 536 TYR n 
2 537 ARG n 
2 538 THR n 
2 539 ILE n 
2 540 ILE n 
2 541 GLY n 
2 542 ASN n 
2 543 GLU n 
2 544 THR n 
2 545 ALA n 
2 546 VAL n 
2 547 ASN n 
2 548 VAL n 
2 549 ASP n 
2 550 SER n 
2 551 SER n 
2 552 HIS n 
2 553 THR n 
2 554 GLU n 
2 555 TYR n 
2 556 THR n 
2 557 LEU n 
2 558 SER n 
2 559 SER n 
2 560 LEU n 
2 561 THR n 
2 562 SER n 
2 563 ASP n 
2 564 THR n 
2 565 LEU n 
2 566 TYR n 
2 567 MET n 
2 568 VAL n 
2 569 ARG n 
2 570 MET n 
2 571 ALA n 
2 572 ALA n 
2 573 TYR n 
2 574 THR n 
2 575 ASP n 
2 576 GLU n 
2 577 GLY n 
2 578 GLY n 
2 579 LYS n 
2 580 ASP n 
2 581 GLY n 
2 582 PRO n 
2 583 GLU n 
2 584 PHE n 
2 585 THR n 
2 586 PHE n 
2 587 THR n 
2 588 THR n 
2 589 PRO n 
2 590 LYS n 
2 591 PHE n 
2 592 ALA n 
2 593 GLN n 
2 594 GLY n 
2 595 GLU n 
2 596 ILE n 
2 597 GLU n 
2 598 GLU n 
2 599 GLN n 
2 600 LYS n 
2 601 LEU n 
2 602 ILE n 
2 603 SER n 
2 604 GLU n 
2 605 GLU n 
2 606 ASP n 
2 607 LEU n 
2 608 GLY n 
2 609 GLY n 
2 610 GLU n 
2 611 GLN n 
2 612 LYS n 
2 613 LEU n 
2 614 ILE n 
2 615 SER n 
2 616 GLU n 
2 617 GLU n 
2 618 ASP n 
2 619 LEU n 
2 620 HIS n 
2 621 HIS n 
2 622 HIS n 
2 623 HIS n 
2 624 HIS n 
2 625 HIS n 
3 1   GLN n 
3 2   LYS n 
3 3   LYS n 
3 4   GLY n 
3 5   ALA n 
3 6   PRO n 
3 7   HIS n 
3 8   ASP n 
3 9   LEU n 
3 10  LYS n 
3 11  CYS n 
3 12  VAL n 
3 13  THR n 
3 14  ASN n 
3 15  ASN n 
3 16  LEU n 
3 17  GLN n 
3 18  VAL n 
3 19  TRP n 
3 20  ASN n 
3 21  CYS n 
3 22  SER n 
3 23  TRP n 
3 24  LYS n 
3 25  ALA n 
3 26  PRO n 
3 27  SER n 
3 28  GLY n 
3 29  THR n 
3 30  GLY n 
3 31  ARG n 
3 32  GLY n 
3 33  THR n 
3 34  ASP n 
3 35  TYR n 
3 36  GLU n 
3 37  VAL n 
3 38  CYS n 
3 39  ILE n 
3 40  GLU n 
3 41  ASN n 
3 42  ARG n 
3 43  SER n 
3 44  ARG n 
3 45  SER n 
3 46  CYS n 
3 47  TYR n 
3 48  GLN n 
3 49  LEU n 
3 50  GLU n 
3 51  LYS n 
3 52  THR n 
3 53  SER n 
3 54  ILE n 
3 55  LYS n 
3 56  ILE n 
3 57  PRO n 
3 58  ALA n 
3 59  LEU n 
3 60  SER n 
3 61  HIS n 
3 62  GLY n 
3 63  ASP n 
3 64  TYR n 
3 65  GLU n 
3 66  ILE n 
3 67  THR n 
3 68  ILE n 
3 69  ASN n 
3 70  SER n 
3 71  LEU n 
3 72  HIS n 
3 73  ASP n 
3 74  PHE n 
3 75  GLY n 
3 76  SER n 
3 77  SER n 
3 78  THR n 
3 79  SER n 
3 80  LYS n 
3 81  PHE n 
3 82  THR n 
3 83  LEU n 
3 84  ASN n 
3 85  GLU n 
3 86  GLN n 
3 87  ASN n 
3 88  VAL n 
3 89  SER n 
3 90  LEU n 
3 91  ILE n 
3 92  PRO n 
3 93  ASP n 
3 94  THR n 
3 95  PRO n 
3 96  GLU n 
3 97  ILE n 
3 98  LEU n 
3 99  ASN n 
3 100 LEU n 
3 101 SER n 
3 102 ALA n 
3 103 ASP n 
3 104 PHE n 
3 105 SER n 
3 106 THR n 
3 107 SER n 
3 108 THR n 
3 109 LEU n 
3 110 TYR n 
3 111 LEU n 
3 112 LYS n 
3 113 TRP n 
3 114 ASN n 
3 115 ASP n 
3 116 ARG n 
3 117 GLY n 
3 118 SER n 
3 119 VAL n 
3 120 PHE n 
3 121 PRO n 
3 122 HIS n 
3 123 ARG n 
3 124 SER n 
3 125 ASN n 
3 126 VAL n 
3 127 ILE n 
3 128 TRP n 
3 129 GLU n 
3 130 ILE n 
3 131 LYS n 
3 132 VAL n 
3 133 LEU n 
3 134 ARG n 
3 135 LYS n 
3 136 GLU n 
3 137 SER n 
3 138 MET n 
3 139 GLU n 
3 140 LEU n 
3 141 VAL n 
3 142 LYS n 
3 143 LEU n 
3 144 VAL n 
3 145 THR n 
3 146 HIS n 
3 147 ASN n 
3 148 THR n 
3 149 THR n 
3 150 LEU n 
3 151 ASN n 
3 152 GLY n 
3 153 LYS n 
3 154 ASP n 
3 155 THR n 
3 156 LEU n 
3 157 HIS n 
3 158 HIS n 
3 159 TRP n 
3 160 SER n 
3 161 TRP n 
3 162 ALA n 
3 163 SER n 
3 164 ASP n 
3 165 MET n 
3 166 PRO n 
3 167 LEU n 
3 168 GLU n 
3 169 CYS n 
3 170 ALA n 
3 171 ILE n 
3 172 HIS n 
3 173 PHE n 
3 174 VAL n 
3 175 GLU n 
3 176 ILE n 
3 177 ARG n 
3 178 CYS n 
3 179 TYR n 
3 180 ILE n 
3 181 ASP n 
3 182 ASN n 
3 183 LEU n 
3 184 HIS n 
3 185 PHE n 
3 186 SER n 
3 187 GLY n 
3 188 LEU n 
3 189 GLU n 
3 190 GLU n 
3 191 TRP n 
3 192 SER n 
3 193 ASP n 
3 194 TRP n 
3 195 SER n 
3 196 PRO n 
3 197 VAL n 
3 198 LYS n 
3 199 ASN n 
3 200 ILE n 
3 201 SER n 
3 202 TRP n 
3 203 ILE n 
3 204 PRO n 
3 205 ASP n 
3 206 SER n 
3 207 GLN n 
3 208 THR n 
3 209 LYS n 
3 210 VAL n 
3 211 PHE n 
3 212 PRO n 
3 213 GLN n 
3 214 ASP n 
3 215 LYS n 
3 216 VAL n 
3 217 ILE n 
3 218 LEU n 
3 219 VAL n 
3 220 GLY n 
3 221 SER n 
3 222 ASP n 
3 223 ILE n 
3 224 THR n 
3 225 PHE n 
3 226 CYS n 
3 227 CYS n 
3 228 VAL n 
3 229 SER n 
3 230 GLN n 
3 231 GLU n 
3 232 LYS n 
3 233 VAL n 
3 234 LEU n 
3 235 SER n 
3 236 ALA n 
3 237 LEU n 
3 238 ILE n 
3 239 GLY n 
3 240 HIS n 
3 241 THR n 
3 242 ASN n 
3 243 CYS n 
3 244 PRO n 
3 245 LEU n 
3 246 ILE n 
3 247 HIS n 
3 248 LEU n 
3 249 ASP n 
3 250 GLY n 
3 251 GLU n 
3 252 ASN n 
3 253 VAL n 
3 254 ALA n 
3 255 ILE n 
3 256 LYS n 
3 257 ILE n 
3 258 ARG n 
3 259 ASN n 
3 260 ILE n 
3 261 SER n 
3 262 VAL n 
3 263 SER n 
3 264 ALA n 
3 265 SER n 
3 266 SER n 
3 267 GLY n 
3 268 THR n 
3 269 ASN n 
3 270 VAL n 
3 271 VAL n 
3 272 PHE n 
3 273 THR n 
3 274 THR n 
3 275 GLU n 
3 276 ASP n 
3 277 ASN n 
3 278 ILE n 
3 279 PHE n 
3 280 GLY n 
3 281 THR n 
3 282 VAL n 
3 283 ILE n 
3 284 PHE n 
3 285 ALA n 
3 286 GLY n 
3 287 TYR n 
3 288 PRO n 
3 289 PRO n 
3 290 ASP n 
3 291 THR n 
3 292 PRO n 
3 293 GLN n 
3 294 GLN n 
3 295 LEU n 
3 296 ASN n 
3 297 CYS n 
3 298 GLU n 
3 299 THR n 
3 300 HIS n 
3 301 ASP n 
3 302 LEU n 
3 303 LYS n 
3 304 GLU n 
3 305 ILE n 
3 306 ILE n 
3 307 CYS n 
3 308 SER n 
3 309 TRP n 
3 310 ASN n 
3 311 PRO n 
3 312 GLY n 
3 313 ARG n 
3 314 VAL n 
3 315 THR n 
3 316 ALA n 
3 317 LEU n 
3 318 VAL n 
3 319 GLY n 
3 320 PRO n 
3 321 ARG n 
3 322 ALA n 
3 323 THR n 
3 324 SER n 
3 325 TYR n 
3 326 THR n 
3 327 LEU n 
3 328 VAL n 
3 329 GLU n 
3 330 SER n 
3 331 PHE n 
3 332 SER n 
3 333 GLY n 
3 334 LYS n 
3 335 TYR n 
3 336 VAL n 
3 337 ARG n 
3 338 LEU n 
3 339 LYS n 
3 340 ARG n 
3 341 ALA n 
3 342 GLU n 
3 343 ALA n 
3 344 PRO n 
3 345 THR n 
3 346 ASN n 
3 347 GLU n 
3 348 SER n 
3 349 TYR n 
3 350 GLN n 
3 351 LEU n 
3 352 LEU n 
3 353 PHE n 
3 354 GLN n 
3 355 MET n 
3 356 LEU n 
3 357 PRO n 
3 358 ASN n 
3 359 GLN n 
3 360 GLU n 
3 361 ILE n 
3 362 TYR n 
3 363 ASN n 
3 364 PHE n 
3 365 THR n 
3 366 LEU n 
3 367 ASN n 
3 368 ALA n 
3 369 HIS n 
3 370 ASN n 
3 371 PRO n 
3 372 LEU n 
3 373 GLY n 
3 374 ARG n 
3 375 SER n 
3 376 GLN n 
3 377 SER n 
3 378 THR n 
3 379 ILE n 
3 380 LEU n 
3 381 VAL n 
3 382 ASN n 
3 383 ILE n 
3 384 THR n 
3 385 GLU n 
3 386 LYS n 
3 387 VAL n 
3 388 TYR n 
3 389 PRO n 
3 390 HIS n 
3 391 THR n 
3 392 PRO n 
3 393 THR n 
3 394 SER n 
3 395 PHE n 
3 396 LYS n 
3 397 VAL n 
3 398 LYS n 
3 399 ASP n 
3 400 ILE n 
3 401 ASN n 
3 402 SER n 
3 403 THR n 
3 404 ALA n 
3 405 VAL n 
3 406 LYS n 
3 407 LEU n 
3 408 SER n 
3 409 TRP n 
3 410 HIS n 
3 411 LEU n 
3 412 PRO n 
3 413 GLY n 
3 414 ASN n 
3 415 PHE n 
3 416 ALA n 
3 417 LYS n 
3 418 ILE n 
3 419 ASN n 
3 420 PHE n 
3 421 LEU n 
3 422 CYS n 
3 423 GLU n 
3 424 ILE n 
3 425 GLU n 
3 426 ILE n 
3 427 LYS n 
3 428 LYS n 
3 429 SER n 
3 430 ASN n 
3 431 SER n 
3 432 VAL n 
3 433 GLN n 
3 434 GLU n 
3 435 GLN n 
3 436 ARG n 
3 437 ASN n 
3 438 VAL n 
3 439 THR n 
3 440 ILE n 
3 441 LYS n 
3 442 GLY n 
3 443 VAL n 
3 444 GLU n 
3 445 ASN n 
3 446 SER n 
3 447 SER n 
3 448 TYR n 
3 449 LEU n 
3 450 VAL n 
3 451 ALA n 
3 452 LEU n 
3 453 ASP n 
3 454 LYS n 
3 455 LEU n 
3 456 ASN n 
3 457 PRO n 
3 458 TYR n 
3 459 THR n 
3 460 LEU n 
3 461 TYR n 
3 462 THR n 
3 463 PHE n 
3 464 ARG n 
3 465 ILE n 
3 466 ARG n 
3 467 CYS n 
3 468 SER n 
3 469 THR n 
3 470 GLU n 
3 471 THR n 
3 472 PHE n 
3 473 TRP n 
3 474 LYS n 
3 475 TRP n 
3 476 SER n 
3 477 LYS n 
3 478 TRP n 
3 479 SER n 
3 480 ASN n 
3 481 LYS n 
3 482 LYS n 
3 483 GLN n 
3 484 HIS n 
3 485 LEU n 
3 486 THR n 
3 487 THR n 
3 488 GLU n 
3 489 ALA n 
3 490 SER n 
3 491 PRO n 
3 492 SER n 
3 493 LYS n 
3 494 GLY n 
3 495 PRO n 
3 496 ASP n 
3 497 THR n 
3 498 TRP n 
3 499 ARG n 
3 500 GLU n 
3 501 TRP n 
3 502 SER n 
3 503 SER n 
3 504 ASP n 
3 505 GLY n 
3 506 LYS n 
3 507 ASN n 
3 508 LEU n 
3 509 ILE n 
3 510 ILE n 
3 511 TYR n 
3 512 TRP n 
3 513 LYS n 
3 514 PRO n 
3 515 LEU n 
3 516 PRO n 
3 517 ILE n 
3 518 ASN n 
3 519 GLU n 
3 520 ALA n 
3 521 ASN n 
3 522 GLY n 
3 523 LYS n 
3 524 ILE n 
3 525 LEU n 
3 526 SER n 
3 527 TYR n 
3 528 ASN n 
3 529 VAL n 
3 530 SER n 
3 531 CYS n 
3 532 SER n 
3 533 SER n 
3 534 ASP n 
3 535 GLU n 
3 536 GLU n 
3 537 THR n 
3 538 GLN n 
3 539 SER n 
3 540 LEU n 
3 541 SER n 
3 542 GLU n 
3 543 ILE n 
3 544 PRO n 
3 545 ASP n 
3 546 PRO n 
3 547 GLN n 
3 548 HIS n 
3 549 LYS n 
3 550 ALA n 
3 551 GLU n 
3 552 ILE n 
3 553 ARG n 
3 554 LEU n 
3 555 ASP n 
3 556 LYS n 
3 557 ASN n 
3 558 ASP n 
3 559 TYR n 
3 560 ILE n 
3 561 ILE n 
3 562 SER n 
3 563 VAL n 
3 564 VAL n 
3 565 ALA n 
3 566 LYS n 
3 567 ASN n 
3 568 SER n 
3 569 VAL n 
3 570 GLY n 
3 571 SER n 
3 572 SER n 
3 573 PRO n 
3 574 PRO n 
3 575 SER n 
3 576 LYS n 
3 577 ILE n 
3 578 ALA n 
3 579 SER n 
3 580 MET n 
3 581 GLU n 
3 582 ILE n 
3 583 PRO n 
3 584 ASN n 
3 585 ASP n 
3 586 ASP n 
3 587 LEU n 
3 588 LYS n 
3 589 ILE n 
3 590 GLU n 
3 591 GLN n 
3 592 VAL n 
3 593 VAL n 
3 594 GLY n 
3 595 MET n 
3 596 GLY n 
3 597 LYS n 
3 598 GLY n 
3 599 ILE n 
3 600 LEU n 
3 601 LEU n 
3 602 THR n 
3 603 TRP n 
3 604 HIS n 
3 605 TYR n 
3 606 ASP n 
3 607 PRO n 
3 608 ASN n 
3 609 MET n 
3 610 THR n 
3 611 CYS n 
3 612 ASP n 
3 613 TYR n 
3 614 VAL n 
3 615 ILE n 
3 616 LYS n 
3 617 TRP n 
3 618 CYS n 
3 619 ASN n 
3 620 SER n 
3 621 SER n 
3 622 ARG n 
3 623 SER n 
3 624 GLU n 
3 625 PRO n 
3 626 CYS n 
3 627 LEU n 
3 628 MET n 
3 629 ASP n 
3 630 TRP n 
3 631 ARG n 
3 632 LYS n 
3 633 VAL n 
3 634 PRO n 
3 635 SER n 
3 636 ASN n 
3 637 SER n 
3 638 THR n 
3 639 GLU n 
3 640 THR n 
3 641 VAL n 
3 642 ILE n 
3 643 GLU n 
3 644 SER n 
3 645 ASP n 
3 646 GLU n 
3 647 PHE n 
3 648 ARG n 
3 649 PRO n 
3 650 GLY n 
3 651 ILE n 
3 652 ARG n 
3 653 TYR n 
3 654 ASN n 
3 655 PHE n 
3 656 PHE n 
3 657 LEU n 
3 658 TYR n 
3 659 GLY n 
3 660 CYS n 
3 661 ARG n 
3 662 ASN n 
3 663 GLN n 
3 664 GLY n 
3 665 TYR n 
3 666 GLN n 
3 667 LEU n 
3 668 LEU n 
3 669 ARG n 
3 670 SER n 
3 671 MET n 
3 672 ILE n 
3 673 GLY n 
3 674 TYR n 
3 675 ILE n 
3 676 GLU n 
3 677 GLU n 
3 678 LEU n 
3 679 ALA n 
3 680 PRO n 
3 681 ILE n 
3 682 VAL n 
3 683 ALA n 
3 684 PRO n 
3 685 ASN n 
3 686 PHE n 
3 687 THR n 
3 688 VAL n 
3 689 GLU n 
3 690 ASP n 
3 691 THR n 
3 692 SER n 
3 693 ALA n 
3 694 ASP n 
3 695 SER n 
3 696 ILE n 
3 697 LEU n 
3 698 VAL n 
3 699 LYS n 
3 700 TRP n 
3 701 GLU n 
3 702 ASP n 
3 703 ILE n 
3 704 PRO n 
3 705 VAL n 
3 706 GLU n 
3 707 GLU n 
3 708 LEU n 
3 709 ARG n 
3 710 GLY n 
3 711 PHE n 
3 712 LEU n 
3 713 ARG n 
3 714 GLY n 
3 715 TYR n 
3 716 LEU n 
3 717 PHE n 
3 718 TYR n 
3 719 PHE n 
3 720 GLY n 
3 721 LYS n 
3 722 GLY n 
3 723 GLU n 
3 724 ARG n 
3 725 ASP n 
3 726 THR n 
3 727 SER n 
3 728 LYS n 
3 729 MET n 
3 730 ARG n 
3 731 VAL n 
3 732 LEU n 
3 733 GLU n 
3 734 SER n 
3 735 GLY n 
3 736 ARG n 
3 737 SER n 
3 738 ASP n 
3 739 ILE n 
3 740 LYS n 
3 741 VAL n 
3 742 LYS n 
3 743 ASN n 
3 744 ILE n 
3 745 THR n 
3 746 ASP n 
3 747 ILE n 
3 748 SER n 
3 749 GLN n 
3 750 LYS n 
3 751 THR n 
3 752 LEU n 
3 753 ARG n 
3 754 ILE n 
3 755 ALA n 
3 756 ASP n 
3 757 LEU n 
3 758 GLN n 
3 759 GLY n 
3 760 LYS n 
3 761 THR n 
3 762 SER n 
3 763 TYR n 
3 764 HIS n 
3 765 LEU n 
3 766 VAL n 
3 767 LEU n 
3 768 ARG n 
3 769 ALA n 
3 770 TYR n 
3 771 THR n 
3 772 ASP n 
3 773 GLY n 
3 774 GLY n 
3 775 VAL n 
3 776 GLY n 
3 777 PRO n 
3 778 GLU n 
3 779 LYS n 
3 780 SER n 
3 781 MET n 
3 782 TYR n 
3 783 VAL n 
3 784 VAL n 
3 785 THR n 
3 786 LYS n 
3 787 GLU n 
3 788 ASN n 
3 789 SER n 
3 790 GLU n 
3 791 GLN n 
3 792 LYS n 
3 793 LEU n 
3 794 ILE n 
3 795 SER n 
3 796 GLU n 
3 797 GLU n 
3 798 ASP n 
3 799 LEU n 
3 800 GLY n 
3 801 GLY n 
3 802 GLU n 
3 803 GLN n 
3 804 LYS n 
3 805 LEU n 
3 806 ILE n 
3 807 SER n 
3 808 GLU n 
3 809 GLU n 
3 810 ASP n 
3 811 LEU n 
3 812 HIS n 
3 813 HIS n 
3 814 HIS n 
3 815 HIS n 
3 816 HIS n 
3 817 HIS n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 196 human ? OSM   ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 'Homo sapiens'       9606  ? 
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 625 human ? IL6ST ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 'Cricetulus griseus' 10029 ? 
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
3 1 sample 'Biological sequence' 1 817 human ? LIFR  ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 'Cricetulus griseus' 10029 ? 
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
_pdbx_entity_branch.entity_id   4 
_pdbx_entity_branch.type        oligosaccharide 
# 
loop_
_pdbx_entity_branch_descriptor.ordinal 
_pdbx_entity_branch_descriptor.entity_id 
_pdbx_entity_branch_descriptor.descriptor 
_pdbx_entity_branch_descriptor.type 
_pdbx_entity_branch_descriptor.program 
_pdbx_entity_branch_descriptor.program_version 
1 4 DGlcpNAcb1-4DGlcpNAcb1-                               'Glycam Condensed Sequence' GMML       1.0   
2 4 'WURCS=2.0/1,2,1/[a2122h-1b_1-5_2*NCC/3=O]/1-1/a4-b1' WURCS                       PDB2Glycan 1.1.0 
3 4 '[]{[(4+1)][b-D-GlcpNAc]{[(4+1)][b-D-GlcpNAc]{}}}'    LINUCS                      PDB-CARE   ?     
# 
_pdbx_entity_branch_link.link_id                    1 
_pdbx_entity_branch_link.entity_id                  4 
_pdbx_entity_branch_link.entity_branch_list_num_1   2 
_pdbx_entity_branch_link.comp_id_1                  NAG 
_pdbx_entity_branch_link.atom_id_1                  C1 
_pdbx_entity_branch_link.leaving_atom_id_1          O1 
_pdbx_entity_branch_link.entity_branch_list_num_2   1 
_pdbx_entity_branch_link.comp_id_2                  NAG 
_pdbx_entity_branch_link.atom_id_2                  O4 
_pdbx_entity_branch_link.leaving_atom_id_2          HO4 
_pdbx_entity_branch_link.value_order                sing 
_pdbx_entity_branch_link.details                    ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking'          y ALANINE                                  ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking'          y ARGININE                                 ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking'          y ASPARAGINE                               ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking'          y 'ASPARTIC ACID'                          ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking'          y CYSTEINE                                 ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking'          y GLUTAMINE                                ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking'          y 'GLUTAMIC ACID'                          ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'            y GLYCINE                                  ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking'          y HISTIDINE                                ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking'          y ISOLEUCINE                               ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking'          y LEUCINE                                  ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking'          y LYSINE                                   ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking'          y METHIONINE                               ? 'C5 H11 N O2 S'  149.211 
NAG 'D-saccharide, beta linking' . 2-acetamido-2-deoxy-beta-D-glucopyranose 
;N-acetyl-beta-D-glucosamine; 2-acetamido-2-deoxy-beta-D-glucose; 2-acetamido-2-deoxy-D-glucose; 2-acetamido-2-deoxy-glucose; N-ACETYL-D-GLUCOSAMINE
;
'C8 H15 N O6'    221.208 
PHE 'L-peptide linking'          y PHENYLALANINE                            ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking'          y PROLINE                                  ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking'          y SERINE                                   ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking'          y THREONINE                                ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking'          y TRYPTOPHAN                               ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking'          y TYROSINE                                 ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking'          y VALINE                                   ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_chem_comp_identifier.comp_id 
_pdbx_chem_comp_identifier.type 
_pdbx_chem_comp_identifier.program 
_pdbx_chem_comp_identifier.program_version 
_pdbx_chem_comp_identifier.identifier 
NAG 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DGlcpNAcb                      
NAG 'COMMON NAME'                         GMML     1.0 N-acetyl-b-D-glucopyranosamine 
NAG 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 b-D-GlcpNAc                    
NAG 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 GlcNAc                         
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   ALA 1   26  26  ALA ALA A . n 
A 1 2   ALA 2   27  27  ALA ALA A . n 
A 1 3   ILE 3   28  28  ILE ILE A . n 
A 1 4   GLY 4   29  29  GLY GLY A . n 
A 1 5   SER 5   30  30  SER SER A . n 
A 1 6   CYS 6   31  31  CYS CYS A . n 
A 1 7   SER 7   32  32  SER SER A . n 
A 1 8   LYS 8   33  33  LYS LYS A . n 
A 1 9   GLU 9   34  34  GLU GLU A . n 
A 1 10  TYR 10  35  35  TYR TYR A . n 
A 1 11  ARG 11  36  36  ARG ARG A . n 
A 1 12  VAL 12  37  37  VAL VAL A . n 
A 1 13  LEU 13  38  38  LEU LEU A . n 
A 1 14  LEU 14  39  39  LEU LEU A . n 
A 1 15  GLY 15  40  40  GLY GLY A . n 
A 1 16  GLN 16  41  41  GLN GLN A . n 
A 1 17  LEU 17  42  42  LEU LEU A . n 
A 1 18  GLN 18  43  43  GLN GLN A . n 
A 1 19  LYS 19  44  44  LYS LYS A . n 
A 1 20  GLN 20  45  45  GLN GLN A . n 
A 1 21  THR 21  46  46  THR THR A . n 
A 1 22  ASP 22  47  47  ASP ASP A . n 
A 1 23  LEU 23  48  48  LEU LEU A . n 
A 1 24  MET 24  49  49  MET MET A . n 
A 1 25  GLN 25  50  50  GLN GLN A . n 
A 1 26  ASP 26  51  51  ASP ASP A . n 
A 1 27  THR 27  52  52  THR THR A . n 
A 1 28  SER 28  53  53  SER SER A . n 
A 1 29  ARG 29  54  54  ARG ARG A . n 
A 1 30  LEU 30  55  55  LEU LEU A . n 
A 1 31  LEU 31  56  56  LEU LEU A . n 
A 1 32  ASP 32  57  57  ASP ASP A . n 
A 1 33  PRO 33  58  58  PRO PRO A . n 
A 1 34  TYR 34  59  59  TYR TYR A . n 
A 1 35  ILE 35  60  60  ILE ILE A . n 
A 1 36  ARG 36  61  61  ARG ARG A . n 
A 1 37  ILE 37  62  62  ILE ILE A . n 
A 1 38  GLN 38  63  63  GLN GLN A . n 
A 1 39  GLY 39  64  64  GLY GLY A . n 
A 1 40  LEU 40  65  65  LEU LEU A . n 
A 1 41  ASP 41  66  66  ASP ASP A . n 
A 1 42  VAL 42  67  67  VAL VAL A . n 
A 1 43  PRO 43  68  68  PRO PRO A . n 
A 1 44  LYS 44  69  69  LYS LYS A . n 
A 1 45  LEU 45  70  70  LEU LEU A . n 
A 1 46  ARG 46  71  71  ARG ARG A . n 
A 1 47  GLU 47  72  72  GLU GLU A . n 
A 1 48  HIS 48  73  73  HIS HIS A . n 
A 1 49  CYS 49  74  74  CYS CYS A . n 
A 1 50  ARG 50  75  75  ARG ARG A . n 
A 1 51  GLU 51  76  76  GLU GLU A . n 
A 1 52  ARG 52  77  77  ARG ARG A . n 
A 1 53  PRO 53  78  78  PRO PRO A . n 
A 1 54  GLY 54  79  79  GLY GLY A . n 
A 1 55  ALA 55  80  80  ALA ALA A . n 
A 1 56  PHE 56  81  81  PHE PHE A . n 
A 1 57  PRO 57  82  82  PRO PRO A . n 
A 1 58  SER 58  83  83  SER SER A . n 
A 1 59  GLU 59  84  84  GLU GLU A . n 
A 1 60  GLU 60  85  85  GLU GLU A . n 
A 1 61  THR 61  86  86  THR THR A . n 
A 1 62  LEU 62  87  87  LEU LEU A . n 
A 1 63  ARG 63  88  88  ARG ARG A . n 
A 1 64  GLY 64  89  89  GLY GLY A . n 
A 1 65  LEU 65  90  90  LEU LEU A . n 
A 1 66  GLY 66  91  91  GLY GLY A . n 
A 1 67  ARG 67  92  92  ARG ARG A . n 
A 1 68  ARG 68  93  93  ARG ARG A . n 
A 1 69  GLY 69  94  94  GLY GLY A . n 
A 1 70  PHE 70  95  95  PHE PHE A . n 
A 1 71  LEU 71  96  96  LEU LEU A . n 
A 1 72  GLN 72  97  97  GLN GLN A . n 
A 1 73  THR 73  98  98  THR THR A . n 
A 1 74  LEU 74  99  99  LEU LEU A . n 
A 1 75  ASN 75  100 100 ASN ASN A . n 
A 1 76  ALA 76  101 101 ALA ALA A . n 
A 1 77  THR 77  102 102 THR THR A . n 
A 1 78  LEU 78  103 103 LEU LEU A . n 
A 1 79  GLY 79  104 104 GLY GLY A . n 
A 1 80  CYS 80  105 105 CYS CYS A . n 
A 1 81  VAL 81  106 106 VAL VAL A . n 
A 1 82  LEU 82  107 107 LEU LEU A . n 
A 1 83  HIS 83  108 108 HIS HIS A . n 
A 1 84  ARG 84  109 109 ARG ARG A . n 
A 1 85  LEU 85  110 110 LEU LEU A . n 
A 1 86  ALA 86  111 111 ALA ALA A . n 
A 1 87  ASP 87  112 112 ASP ASP A . n 
A 1 88  LEU 88  113 113 LEU LEU A . n 
A 1 89  GLU 89  114 114 GLU GLU A . n 
A 1 90  GLN 90  115 115 GLN GLN A . n 
A 1 91  ARG 91  116 116 ARG ARG A . n 
A 1 92  LEU 92  117 117 LEU LEU A . n 
A 1 93  PRO 93  118 118 PRO PRO A . n 
A 1 94  LYS 94  119 119 LYS LYS A . n 
A 1 95  ALA 95  120 120 ALA ALA A . n 
A 1 96  GLN 96  121 121 GLN GLN A . n 
A 1 97  ASP 97  122 122 ASP ASP A . n 
A 1 98  LEU 98  123 123 LEU LEU A . n 
A 1 99  GLU 99  124 124 GLU GLU A . n 
A 1 100 ARG 100 125 125 ARG ARG A . n 
A 1 101 SER 101 126 126 SER SER A . n 
A 1 102 GLY 102 127 127 GLY GLY A . n 
A 1 103 LEU 103 128 128 LEU LEU A . n 
A 1 104 ASN 104 129 129 ASN ASN A . n 
A 1 105 ILE 105 130 130 ILE ILE A . n 
A 1 106 GLU 106 131 131 GLU GLU A . n 
A 1 107 ASP 107 132 132 ASP ASP A . n 
A 1 108 LEU 108 133 133 LEU LEU A . n 
A 1 109 GLU 109 134 134 GLU GLU A . n 
A 1 110 LYS 110 135 135 LYS LYS A . n 
A 1 111 LEU 111 136 136 LEU LEU A . n 
A 1 112 GLN 112 137 137 GLN GLN A . n 
A 1 113 MET 113 138 138 MET MET A . n 
A 1 114 ALA 114 139 139 ALA ALA A . n 
A 1 115 ARG 115 140 140 ARG ARG A . n 
A 1 116 PRO 116 141 141 PRO PRO A . n 
A 1 117 ASN 117 142 142 ASN ASN A . n 
A 1 118 ILE 118 143 143 ILE ILE A . n 
A 1 119 LEU 119 144 144 LEU LEU A . n 
A 1 120 GLY 120 145 145 GLY GLY A . n 
A 1 121 LEU 121 146 146 LEU LEU A . n 
A 1 122 ARG 122 147 147 ARG ARG A . n 
A 1 123 ASN 123 148 148 ASN ASN A . n 
A 1 124 ASN 124 149 149 ASN ASN A . n 
A 1 125 ILE 125 150 150 ILE ILE A . n 
A 1 126 TYR 126 151 151 TYR TYR A . n 
A 1 127 CYS 127 152 152 CYS CYS A . n 
A 1 128 MET 128 153 153 MET MET A . n 
A 1 129 ALA 129 154 154 ALA ALA A . n 
A 1 130 GLN 130 155 155 GLN GLN A . n 
A 1 131 LEU 131 156 156 LEU LEU A . n 
A 1 132 LEU 132 157 157 LEU LEU A . n 
A 1 133 ASP 133 158 158 ASP ASP A . n 
A 1 134 ASN 134 159 159 ASN ASN A . n 
A 1 135 SER 135 160 ?   ?   ?   A . n 
A 1 136 ASP 136 161 ?   ?   ?   A . n 
A 1 137 THR 137 162 ?   ?   ?   A . n 
A 1 138 ALA 138 163 ?   ?   ?   A . n 
A 1 139 GLU 139 164 ?   ?   ?   A . n 
A 1 140 PRO 140 165 ?   ?   ?   A . n 
A 1 141 THR 141 166 ?   ?   ?   A . n 
A 1 142 LYS 142 167 ?   ?   ?   A . n 
A 1 143 ALA 143 168 ?   ?   ?   A . n 
A 1 144 GLY 144 169 ?   ?   ?   A . n 
A 1 145 ARG 145 170 ?   ?   ?   A . n 
A 1 146 GLY 146 171 ?   ?   ?   A . n 
A 1 147 ALA 147 172 ?   ?   ?   A . n 
A 1 148 SER 148 173 ?   ?   ?   A . n 
A 1 149 GLN 149 174 ?   ?   ?   A . n 
A 1 150 PRO 150 175 ?   ?   ?   A . n 
A 1 151 PRO 151 176 ?   ?   ?   A . n 
A 1 152 THR 152 177 ?   ?   ?   A . n 
A 1 153 PRO 153 178 ?   ?   ?   A . n 
A 1 154 THR 154 179 179 THR THR A . n 
A 1 155 PRO 155 180 180 PRO PRO A . n 
A 1 156 ALA 156 181 181 ALA ALA A . n 
A 1 157 SER 157 182 182 SER SER A . n 
A 1 158 ASP 158 183 183 ASP ASP A . n 
A 1 159 ALA 159 184 184 ALA ALA A . n 
A 1 160 PHE 160 185 185 PHE PHE A . n 
A 1 161 GLN 161 186 186 GLN GLN A . n 
A 1 162 ARG 162 187 187 ARG ARG A . n 
A 1 163 LYS 163 188 188 LYS LYS A . n 
A 1 164 LEU 164 189 189 LEU LEU A . n 
A 1 165 GLU 165 190 190 GLU GLU A . n 
A 1 166 GLY 166 191 191 GLY GLY A . n 
A 1 167 CYS 167 192 192 CYS CYS A . n 
A 1 168 ARG 168 193 193 ARG ARG A . n 
A 1 169 PHE 169 194 194 PHE PHE A . n 
A 1 170 LEU 170 195 195 LEU LEU A . n 
A 1 171 HIS 171 196 196 HIS HIS A . n 
A 1 172 GLY 172 197 197 GLY GLY A . n 
A 1 173 TYR 173 198 198 TYR TYR A . n 
A 1 174 HIS 174 199 199 HIS HIS A . n 
A 1 175 ARG 175 200 200 ARG ARG A . n 
A 1 176 PHE 176 201 201 PHE PHE A . n 
A 1 177 MET 177 202 202 MET MET A . n 
A 1 178 HIS 178 203 203 HIS HIS A . n 
A 1 179 SER 179 204 204 SER SER A . n 
A 1 180 VAL 180 205 205 VAL VAL A . n 
A 1 181 GLY 181 206 206 GLY GLY A . n 
A 1 182 ARG 182 207 207 ARG ARG A . n 
A 1 183 VAL 183 208 208 VAL VAL A . n 
A 1 184 PHE 184 209 209 PHE PHE A . n 
A 1 185 SER 185 210 210 SER SER A . n 
A 1 186 LYS 186 211 211 LYS LYS A . n 
A 1 187 TRP 187 212 212 TRP TRP A . n 
A 1 188 GLY 188 213 213 GLY GLY A . n 
A 1 189 GLU 189 214 214 GLU GLU A . n 
A 1 190 SER 190 215 215 SER SER A . n 
A 1 191 PRO 191 216 216 PRO PRO A . n 
A 1 192 ASN 192 217 ?   ?   ?   A . n 
A 1 193 ARG 193 218 ?   ?   ?   A . n 
A 1 194 SER 194 219 ?   ?   ?   A . n 
A 1 195 ARG 195 220 ?   ?   ?   A . n 
A 1 196 ARG 196 221 ?   ?   ?   A . n 
B 2 1   GLU 1   23  ?   ?   ?   B . n 
B 2 2   LEU 2   24  ?   ?   ?   B . n 
B 2 3   LEU 3   25  ?   ?   ?   B . n 
B 2 4   ASP 4   26  ?   ?   ?   B . n 
B 2 5   PRO 5   27  27  PRO PRO B . n 
B 2 6   CYS 6   28  28  CYS CYS B . n 
B 2 7   GLY 7   29  29  GLY GLY B . n 
B 2 8   TYR 8   30  30  TYR TYR B . n 
B 2 9   ILE 9   31  31  ILE ILE B . n 
B 2 10  SER 10  32  32  SER SER B . n 
B 2 11  PRO 11  33  33  PRO PRO B . n 
B 2 12  GLU 12  34  34  GLU GLU B . n 
B 2 13  SER 13  35  35  SER SER B . n 
B 2 14  PRO 14  36  36  PRO PRO B . n 
B 2 15  VAL 15  37  37  VAL VAL B . n 
B 2 16  VAL 16  38  38  VAL VAL B . n 
B 2 17  GLN 17  39  39  GLN GLN B . n 
B 2 18  LEU 18  40  40  LEU LEU B . n 
B 2 19  HIS 19  41  41  HIS HIS B . n 
B 2 20  SER 20  42  42  SER SER B . n 
B 2 21  ASN 21  43  43  ASN ASN B . n 
B 2 22  PHE 22  44  44  PHE PHE B . n 
B 2 23  THR 23  45  45  THR THR B . n 
B 2 24  ALA 24  46  46  ALA ALA B . n 
B 2 25  VAL 25  47  47  VAL VAL B . n 
B 2 26  CYS 26  48  48  CYS CYS B . n 
B 2 27  VAL 27  49  49  VAL VAL B . n 
B 2 28  LEU 28  50  50  LEU LEU B . n 
B 2 29  LYS 29  51  51  LYS LYS B . n 
B 2 30  GLU 30  52  52  GLU GLU B . n 
B 2 31  LYS 31  53  53  LYS LYS B . n 
B 2 32  CYS 32  54  54  CYS CYS B . n 
B 2 33  MET 33  55  55  MET MET B . n 
B 2 34  ASP 34  56  56  ASP ASP B . n 
B 2 35  TYR 35  57  57  TYR TYR B . n 
B 2 36  PHE 36  58  58  PHE PHE B . n 
B 2 37  HIS 37  59  59  HIS HIS B . n 
B 2 38  VAL 38  60  60  VAL VAL B . n 
B 2 39  ASN 39  61  61  ASN ASN B . n 
B 2 40  ALA 40  62  62  ALA ALA B . n 
B 2 41  ASN 41  63  63  ASN ASN B . n 
B 2 42  TYR 42  64  64  TYR TYR B . n 
B 2 43  ILE 43  65  65  ILE ILE B . n 
B 2 44  VAL 44  66  66  VAL VAL B . n 
B 2 45  TRP 45  67  67  TRP TRP B . n 
B 2 46  LYS 46  68  68  LYS LYS B . n 
B 2 47  THR 47  69  69  THR THR B . n 
B 2 48  ASN 48  70  70  ASN ASN B . n 
B 2 49  HIS 49  71  71  HIS HIS B . n 
B 2 50  PHE 50  72  72  PHE PHE B . n 
B 2 51  THR 51  73  73  THR THR B . n 
B 2 52  ILE 52  74  74  ILE ILE B . n 
B 2 53  PRO 53  75  75  PRO PRO B . n 
B 2 54  LYS 54  76  76  LYS LYS B . n 
B 2 55  GLU 55  77  77  GLU GLU B . n 
B 2 56  GLN 56  78  78  GLN GLN B . n 
B 2 57  TYR 57  79  79  TYR TYR B . n 
B 2 58  THR 58  80  80  THR THR B . n 
B 2 59  ILE 59  81  81  ILE ILE B . n 
B 2 60  ILE 60  82  82  ILE ILE B . n 
B 2 61  ASN 61  83  83  ASN ASN B . n 
B 2 62  ARG 62  84  84  ARG ARG B . n 
B 2 63  THR 63  85  85  THR THR B . n 
B 2 64  ALA 64  86  86  ALA ALA B . n 
B 2 65  SER 65  87  87  SER SER B . n 
B 2 66  SER 66  88  88  SER SER B . n 
B 2 67  VAL 67  89  89  VAL VAL B . n 
B 2 68  THR 68  90  90  THR THR B . n 
B 2 69  PHE 69  91  91  PHE PHE B . n 
B 2 70  THR 70  92  92  THR THR B . n 
B 2 71  ASP 71  93  93  ASP ASP B . n 
B 2 72  ILE 72  94  94  ILE ILE B . n 
B 2 73  ALA 73  95  95  ALA ALA B . n 
B 2 74  SER 74  96  96  SER SER B . n 
B 2 75  LEU 75  97  97  LEU LEU B . n 
B 2 76  ASN 76  98  98  ASN ASN B . n 
B 2 77  ILE 77  99  99  ILE ILE B . n 
B 2 78  GLN 78  100 100 GLN GLN B . n 
B 2 79  LEU 79  101 101 LEU LEU B . n 
B 2 80  THR 80  102 102 THR THR B . n 
B 2 81  CYS 81  103 103 CYS CYS B . n 
B 2 82  ASN 82  104 104 ASN ASN B . n 
B 2 83  ILE 83  105 105 ILE ILE B . n 
B 2 84  LEU 84  106 106 LEU LEU B . n 
B 2 85  THR 85  107 107 THR THR B . n 
B 2 86  PHE 86  108 108 PHE PHE B . n 
B 2 87  GLY 87  109 109 GLY GLY B . n 
B 2 88  GLN 88  110 110 GLN GLN B . n 
B 2 89  LEU 89  111 111 LEU LEU B . n 
B 2 90  GLU 90  112 112 GLU GLU B . n 
B 2 91  GLN 91  113 113 GLN GLN B . n 
B 2 92  ASN 92  114 114 ASN ASN B . n 
B 2 93  VAL 93  115 115 VAL VAL B . n 
B 2 94  TYR 94  116 116 TYR TYR B . n 
B 2 95  GLY 95  117 117 GLY GLY B . n 
B 2 96  ILE 96  118 118 ILE ILE B . n 
B 2 97  THR 97  119 119 THR THR B . n 
B 2 98  ILE 98  120 120 ILE ILE B . n 
B 2 99  ILE 99  121 121 ILE ILE B . n 
B 2 100 SER 100 122 122 SER SER B . n 
B 2 101 GLY 101 123 123 GLY GLY B . n 
B 2 102 LEU 102 124 124 LEU LEU B . n 
B 2 103 PRO 103 125 125 PRO PRO B . n 
B 2 104 PRO 104 126 126 PRO PRO B . n 
B 2 105 GLU 105 127 127 GLU GLU B . n 
B 2 106 LYS 106 128 128 LYS LYS B . n 
B 2 107 PRO 107 129 129 PRO PRO B . n 
B 2 108 LYS 108 130 130 LYS LYS B . n 
B 2 109 ASN 109 131 131 ASN ASN B . n 
B 2 110 LEU 110 132 132 LEU LEU B . n 
B 2 111 SER 111 133 133 SER SER B . n 
B 2 112 CYS 112 134 134 CYS CYS B . n 
B 2 113 ILE 113 135 135 ILE ILE B . n 
B 2 114 VAL 114 136 136 VAL VAL B . n 
B 2 115 ASN 115 137 137 ASN ASN B . n 
B 2 116 GLU 116 138 138 GLU GLU B . n 
B 2 117 GLY 117 139 139 GLY GLY B . n 
B 2 118 LYS 118 140 140 LYS LYS B . n 
B 2 119 LYS 119 141 141 LYS LYS B . n 
B 2 120 MET 120 142 142 MET MET B . n 
B 2 121 ARG 121 143 143 ARG ARG B . n 
B 2 122 CYS 122 144 144 CYS CYS B . n 
B 2 123 GLU 123 145 145 GLU GLU B . n 
B 2 124 TRP 124 146 146 TRP TRP B . n 
B 2 125 ASP 125 147 147 ASP ASP B . n 
B 2 126 GLY 126 148 148 GLY GLY B . n 
B 2 127 GLY 127 149 149 GLY GLY B . n 
B 2 128 ARG 128 150 150 ARG ARG B . n 
B 2 129 GLU 129 151 151 GLU GLU B . n 
B 2 130 THR 130 152 152 THR THR B . n 
B 2 131 HIS 131 153 153 HIS HIS B . n 
B 2 132 LEU 132 154 154 LEU LEU B . n 
B 2 133 GLU 133 155 155 GLU GLU B . n 
B 2 134 THR 134 156 156 THR THR B . n 
B 2 135 ASN 135 157 157 ASN ASN B . n 
B 2 136 PHE 136 158 158 PHE PHE B . n 
B 2 137 THR 137 159 159 THR THR B . n 
B 2 138 LEU 138 160 160 LEU LEU B . n 
B 2 139 LYS 139 161 161 LYS LYS B . n 
B 2 140 SER 140 162 162 SER SER B . n 
B 2 141 GLU 141 163 163 GLU GLU B . n 
B 2 142 TRP 142 164 164 TRP TRP B . n 
B 2 143 ALA 143 165 165 ALA ALA B . n 
B 2 144 THR 144 166 166 THR THR B . n 
B 2 145 HIS 145 167 167 HIS HIS B . n 
B 2 146 LYS 146 168 168 LYS LYS B . n 
B 2 147 PHE 147 169 169 PHE PHE B . n 
B 2 148 ALA 148 170 170 ALA ALA B . n 
B 2 149 ASP 149 171 171 ASP ASP B . n 
B 2 150 CYS 150 172 172 CYS CYS B . n 
B 2 151 LYS 151 173 173 LYS LYS B . n 
B 2 152 ALA 152 174 174 ALA ALA B . n 
B 2 153 LYS 153 175 175 LYS LYS B . n 
B 2 154 ARG 154 176 176 ARG ARG B . n 
B 2 155 ASP 155 177 177 ASP ASP B . n 
B 2 156 THR 156 178 178 THR THR B . n 
B 2 157 PRO 157 179 179 PRO PRO B . n 
B 2 158 THR 158 180 180 THR THR B . n 
B 2 159 SER 159 181 181 SER SER B . n 
B 2 160 CYS 160 182 182 CYS CYS B . n 
B 2 161 THR 161 183 183 THR THR B . n 
B 2 162 VAL 162 184 184 VAL VAL B . n 
B 2 163 ASP 163 185 185 ASP ASP B . n 
B 2 164 TYR 164 186 186 TYR TYR B . n 
B 2 165 SER 165 187 187 SER SER B . n 
B 2 166 THR 166 188 188 THR THR B . n 
B 2 167 VAL 167 189 189 VAL VAL B . n 
B 2 168 TYR 168 190 190 TYR TYR B . n 
B 2 169 PHE 169 191 191 PHE PHE B . n 
B 2 170 VAL 170 192 192 VAL VAL B . n 
B 2 171 ASN 171 193 193 ASN ASN B . n 
B 2 172 ILE 172 194 194 ILE ILE B . n 
B 2 173 GLU 173 195 195 GLU GLU B . n 
B 2 174 VAL 174 196 196 VAL VAL B . n 
B 2 175 TRP 175 197 197 TRP TRP B . n 
B 2 176 VAL 176 198 198 VAL VAL B . n 
B 2 177 GLU 177 199 199 GLU GLU B . n 
B 2 178 ALA 178 200 200 ALA ALA B . n 
B 2 179 GLU 179 201 201 GLU GLU B . n 
B 2 180 ASN 180 202 202 ASN ASN B . n 
B 2 181 ALA 181 203 203 ALA ALA B . n 
B 2 182 LEU 182 204 204 LEU LEU B . n 
B 2 183 GLY 183 205 205 GLY GLY B . n 
B 2 184 LYS 184 206 206 LYS LYS B . n 
B 2 185 VAL 185 207 207 VAL VAL B . n 
B 2 186 THR 186 208 208 THR THR B . n 
B 2 187 SER 187 209 209 SER SER B . n 
B 2 188 ASP 188 210 210 ASP ASP B . n 
B 2 189 HIS 189 211 211 HIS HIS B . n 
B 2 190 ILE 190 212 212 ILE ILE B . n 
B 2 191 ASN 191 213 213 ASN ASN B . n 
B 2 192 PHE 192 214 214 PHE PHE B . n 
B 2 193 ASP 193 215 215 ASP ASP B . n 
B 2 194 PRO 194 216 216 PRO PRO B . n 
B 2 195 VAL 195 217 217 VAL VAL B . n 
B 2 196 TYR 196 218 218 TYR TYR B . n 
B 2 197 LYS 197 219 219 LYS LYS B . n 
B 2 198 VAL 198 220 220 VAL VAL B . n 
B 2 199 LYS 199 221 221 LYS LYS B . n 
B 2 200 PRO 200 222 222 PRO PRO B . n 
B 2 201 ASN 201 223 223 ASN ASN B . n 
B 2 202 PRO 202 224 224 PRO PRO B . n 
B 2 203 PRO 203 225 225 PRO PRO B . n 
B 2 204 HIS 204 226 226 HIS HIS B . n 
B 2 205 ASN 205 227 227 ASN ASN B . n 
B 2 206 LEU 206 228 228 LEU LEU B . n 
B 2 207 SER 207 229 229 SER SER B . n 
B 2 208 VAL 208 230 230 VAL VAL B . n 
B 2 209 ILE 209 231 231 ILE ILE B . n 
B 2 210 ASN 210 232 232 ASN ASN B . n 
B 2 211 SER 211 233 233 SER SER B . n 
B 2 212 GLU 212 234 234 GLU GLU B . n 
B 2 213 GLU 213 235 235 GLU GLU B . n 
B 2 214 LEU 214 236 236 LEU LEU B . n 
B 2 215 SER 215 237 237 SER SER B . n 
B 2 216 SER 216 238 238 SER SER B . n 
B 2 217 ILE 217 239 239 ILE ILE B . n 
B 2 218 LEU 218 240 240 LEU LEU B . n 
B 2 219 LYS 219 241 241 LYS LYS B . n 
B 2 220 LEU 220 242 242 LEU LEU B . n 
B 2 221 THR 221 243 243 THR THR B . n 
B 2 222 TRP 222 244 244 TRP TRP B . n 
B 2 223 THR 223 245 245 THR THR B . n 
B 2 224 ASN 224 246 246 ASN ASN B . n 
B 2 225 PRO 225 247 247 PRO PRO B . n 
B 2 226 SER 226 248 248 SER SER B . n 
B 2 227 ILE 227 249 249 ILE ILE B . n 
B 2 228 LYS 228 250 250 LYS LYS B . n 
B 2 229 SER 229 251 251 SER SER B . n 
B 2 230 VAL 230 252 252 VAL VAL B . n 
B 2 231 ILE 231 253 253 ILE ILE B . n 
B 2 232 ILE 232 254 254 ILE ILE B . n 
B 2 233 LEU 233 255 255 LEU LEU B . n 
B 2 234 LYS 234 256 256 LYS LYS B . n 
B 2 235 TYR 235 257 257 TYR TYR B . n 
B 2 236 ASN 236 258 258 ASN ASN B . n 
B 2 237 ILE 237 259 259 ILE ILE B . n 
B 2 238 GLN 238 260 260 GLN GLN B . n 
B 2 239 TYR 239 261 261 TYR TYR B . n 
B 2 240 ARG 240 262 262 ARG ARG B . n 
B 2 241 THR 241 263 263 THR THR B . n 
B 2 242 LYS 242 264 264 LYS LYS B . n 
B 2 243 ASP 243 265 265 ASP ASP B . n 
B 2 244 ALA 244 266 266 ALA ALA B . n 
B 2 245 SER 245 267 267 SER SER B . n 
B 2 246 THR 246 268 268 THR THR B . n 
B 2 247 TRP 247 269 269 TRP TRP B . n 
B 2 248 SER 248 270 270 SER SER B . n 
B 2 249 GLN 249 271 271 GLN GLN B . n 
B 2 250 ILE 250 272 272 ILE ILE B . n 
B 2 251 PRO 251 273 273 PRO PRO B . n 
B 2 252 PRO 252 274 274 PRO PRO B . n 
B 2 253 GLU 253 275 275 GLU GLU B . n 
B 2 254 ASP 254 276 276 ASP ASP B . n 
B 2 255 THR 255 277 277 THR THR B . n 
B 2 256 ALA 256 278 278 ALA ALA B . n 
B 2 257 SER 257 279 279 SER SER B . n 
B 2 258 THR 258 280 280 THR THR B . n 
B 2 259 ARG 259 281 281 ARG ARG B . n 
B 2 260 SER 260 282 282 SER SER B . n 
B 2 261 SER 261 283 283 SER SER B . n 
B 2 262 PHE 262 284 284 PHE PHE B . n 
B 2 263 THR 263 285 285 THR THR B . n 
B 2 264 VAL 264 286 286 VAL VAL B . n 
B 2 265 GLN 265 287 287 GLN GLN B . n 
B 2 266 ASP 266 288 288 ASP ASP B . n 
B 2 267 LEU 267 289 289 LEU LEU B . n 
B 2 268 LYS 268 290 290 LYS LYS B . n 
B 2 269 PRO 269 291 291 PRO PRO B . n 
B 2 270 PHE 270 292 292 PHE PHE B . n 
B 2 271 THR 271 293 293 THR THR B . n 
B 2 272 GLU 272 294 294 GLU GLU B . n 
B 2 273 TYR 273 295 295 TYR TYR B . n 
B 2 274 VAL 274 296 296 VAL VAL B . n 
B 2 275 PHE 275 297 297 PHE PHE B . n 
B 2 276 ARG 276 298 298 ARG ARG B . n 
B 2 277 ILE 277 299 299 ILE ILE B . n 
B 2 278 ARG 278 300 300 ARG ARG B . n 
B 2 279 CYS 279 301 301 CYS CYS B . n 
B 2 280 MET 280 302 302 MET MET B . n 
B 2 281 LYS 281 303 303 LYS LYS B . n 
B 2 282 GLU 282 304 304 GLU GLU B . n 
B 2 283 ASP 283 305 305 ASP ASP B . n 
B 2 284 GLY 284 306 306 GLY GLY B . n 
B 2 285 LYS 285 307 307 LYS LYS B . n 
B 2 286 GLY 286 308 308 GLY GLY B . n 
B 2 287 TYR 287 309 309 TYR TYR B . n 
B 2 288 TRP 288 310 310 TRP TRP B . n 
B 2 289 SER 289 311 311 SER SER B . n 
B 2 290 ASP 290 312 312 ASP ASP B . n 
B 2 291 TRP 291 313 313 TRP TRP B . n 
B 2 292 SER 292 314 314 SER SER B . n 
B 2 293 GLU 293 315 315 GLU GLU B . n 
B 2 294 GLU 294 316 316 GLU GLU B . n 
B 2 295 ALA 295 317 317 ALA ALA B . n 
B 2 296 SER 296 318 318 SER SER B . n 
B 2 297 GLY 297 319 319 GLY GLY B . n 
B 2 298 ILE 298 320 320 ILE ILE B . n 
B 2 299 THR 299 321 321 THR THR B . n 
B 2 300 TYR 300 322 322 TYR TYR B . n 
B 2 301 GLU 301 323 323 GLU GLU B . n 
B 2 302 ASP 302 324 324 ASP ASP B . n 
B 2 303 ARG 303 325 325 ARG ARG B . n 
B 2 304 PRO 304 326 326 PRO PRO B . n 
B 2 305 SER 305 327 327 SER SER B . n 
B 2 306 LYS 306 328 328 LYS LYS B . n 
B 2 307 ALA 307 329 329 ALA ALA B . n 
B 2 308 PRO 308 330 330 PRO PRO B . n 
B 2 309 SER 309 331 331 SER SER B . n 
B 2 310 PHE 310 332 332 PHE PHE B . n 
B 2 311 TRP 311 333 333 TRP TRP B . n 
B 2 312 TYR 312 334 334 TYR TYR B . n 
B 2 313 LYS 313 335 335 LYS LYS B . n 
B 2 314 ILE 314 336 336 ILE ILE B . n 
B 2 315 ASP 315 337 337 ASP ASP B . n 
B 2 316 PRO 316 338 338 PRO PRO B . n 
B 2 317 SER 317 339 339 SER SER B . n 
B 2 318 HIS 318 340 340 HIS HIS B . n 
B 2 319 THR 319 341 341 THR THR B . n 
B 2 320 GLN 320 342 342 GLN GLN B . n 
B 2 321 GLY 321 343 343 GLY GLY B . n 
B 2 322 TYR 322 344 344 TYR TYR B . n 
B 2 323 ARG 323 345 345 ARG ARG B . n 
B 2 324 THR 324 346 346 THR THR B . n 
B 2 325 VAL 325 347 347 VAL VAL B . n 
B 2 326 GLN 326 348 348 GLN GLN B . n 
B 2 327 LEU 327 349 349 LEU LEU B . n 
B 2 328 VAL 328 350 350 VAL VAL B . n 
B 2 329 TRP 329 351 351 TRP TRP B . n 
B 2 330 LYS 330 352 352 LYS LYS B . n 
B 2 331 THR 331 353 353 THR THR B . n 
B 2 332 LEU 332 354 354 LEU LEU B . n 
B 2 333 PRO 333 355 355 PRO PRO B . n 
B 2 334 PRO 334 356 356 PRO PRO B . n 
B 2 335 PHE 335 357 357 PHE PHE B . n 
B 2 336 GLU 336 358 358 GLU GLU B . n 
B 2 337 ALA 337 359 359 ALA ALA B . n 
B 2 338 ASN 338 360 360 ASN ASN B . n 
B 2 339 GLY 339 361 361 GLY GLY B . n 
B 2 340 LYS 340 362 362 LYS LYS B . n 
B 2 341 ILE 341 363 363 ILE ILE B . n 
B 2 342 LEU 342 364 364 LEU LEU B . n 
B 2 343 ASP 343 365 365 ASP ASP B . n 
B 2 344 TYR 344 366 366 TYR TYR B . n 
B 2 345 GLU 345 367 367 GLU GLU B . n 
B 2 346 VAL 346 368 368 VAL VAL B . n 
B 2 347 THR 347 369 369 THR THR B . n 
B 2 348 LEU 348 370 370 LEU LEU B . n 
B 2 349 THR 349 371 371 THR THR B . n 
B 2 350 ARG 350 372 372 ARG ARG B . n 
B 2 351 TRP 351 373 373 TRP TRP B . n 
B 2 352 LYS 352 374 374 LYS LYS B . n 
B 2 353 SER 353 375 375 SER SER B . n 
B 2 354 HIS 354 376 376 HIS HIS B . n 
B 2 355 LEU 355 377 377 LEU LEU B . n 
B 2 356 GLN 356 378 378 GLN GLN B . n 
B 2 357 ASN 357 379 379 ASN ASN B . n 
B 2 358 TYR 358 380 380 TYR TYR B . n 
B 2 359 THR 359 381 381 THR THR B . n 
B 2 360 VAL 360 382 382 VAL VAL B . n 
B 2 361 ASN 361 383 383 ASN ASN B . n 
B 2 362 ALA 362 384 384 ALA ALA B . n 
B 2 363 THR 363 385 385 THR THR B . n 
B 2 364 LYS 364 386 386 LYS LYS B . n 
B 2 365 LEU 365 387 387 LEU LEU B . n 
B 2 366 THR 366 388 388 THR THR B . n 
B 2 367 VAL 367 389 389 VAL VAL B . n 
B 2 368 ASN 368 390 390 ASN ASN B . n 
B 2 369 LEU 369 391 391 LEU LEU B . n 
B 2 370 THR 370 392 392 THR THR B . n 
B 2 371 ASN 371 393 393 ASN ASN B . n 
B 2 372 ASP 372 394 394 ASP ASP B . n 
B 2 373 ARG 373 395 395 ARG ARG B . n 
B 2 374 TYR 374 396 396 TYR TYR B . n 
B 2 375 LEU 375 397 397 LEU LEU B . n 
B 2 376 ALA 376 398 398 ALA ALA B . n 
B 2 377 THR 377 399 399 THR THR B . n 
B 2 378 LEU 378 400 400 LEU LEU B . n 
B 2 379 THR 379 401 401 THR THR B . n 
B 2 380 VAL 380 402 402 VAL VAL B . n 
B 2 381 ARG 381 403 403 ARG ARG B . n 
B 2 382 ASN 382 404 404 ASN ASN B . n 
B 2 383 LEU 383 405 405 LEU LEU B . n 
B 2 384 VAL 384 406 406 VAL VAL B . n 
B 2 385 GLY 385 407 407 GLY GLY B . n 
B 2 386 LYS 386 408 408 LYS LYS B . n 
B 2 387 SER 387 409 409 SER SER B . n 
B 2 388 ASP 388 410 410 ASP ASP B . n 
B 2 389 ALA 389 411 411 ALA ALA B . n 
B 2 390 ALA 390 412 412 ALA ALA B . n 
B 2 391 VAL 391 413 413 VAL VAL B . n 
B 2 392 LEU 392 414 414 LEU LEU B . n 
B 2 393 THR 393 415 415 THR THR B . n 
B 2 394 ILE 394 416 416 ILE ILE B . n 
B 2 395 PRO 395 417 417 PRO PRO B . n 
B 2 396 ALA 396 418 418 ALA ALA B . n 
B 2 397 CYS 397 419 419 CYS CYS B . n 
B 2 398 ASP 398 420 420 ASP ASP B . n 
B 2 399 PHE 399 421 421 PHE PHE B . n 
B 2 400 GLN 400 422 422 GLN GLN B . n 
B 2 401 ALA 401 423 423 ALA ALA B . n 
B 2 402 THR 402 424 424 THR THR B . n 
B 2 403 HIS 403 425 425 HIS HIS B . n 
B 2 404 PRO 404 426 426 PRO PRO B . n 
B 2 405 VAL 405 427 427 VAL VAL B . n 
B 2 406 MET 406 428 428 MET MET B . n 
B 2 407 ASP 407 429 429 ASP ASP B . n 
B 2 408 LEU 408 430 430 LEU LEU B . n 
B 2 409 LYS 409 431 431 LYS LYS B . n 
B 2 410 ALA 410 432 432 ALA ALA B . n 
B 2 411 PHE 411 433 433 PHE PHE B . n 
B 2 412 PRO 412 434 434 PRO PRO B . n 
B 2 413 LYS 413 435 435 LYS LYS B . n 
B 2 414 ASP 414 436 436 ASP ASP B . n 
B 2 415 ASN 415 437 437 ASN ASN B . n 
B 2 416 MET 416 438 438 MET MET B . n 
B 2 417 LEU 417 439 439 LEU LEU B . n 
B 2 418 TRP 418 440 440 TRP TRP B . n 
B 2 419 VAL 419 441 441 VAL VAL B . n 
B 2 420 GLU 420 442 442 GLU GLU B . n 
B 2 421 TRP 421 443 443 TRP TRP B . n 
B 2 422 THR 422 444 444 THR THR B . n 
B 2 423 THR 423 445 445 THR THR B . n 
B 2 424 PRO 424 446 446 PRO PRO B . n 
B 2 425 ARG 425 447 447 ARG ARG B . n 
B 2 426 GLU 426 448 448 GLU GLU B . n 
B 2 427 SER 427 449 449 SER SER B . n 
B 2 428 VAL 428 450 450 VAL VAL B . n 
B 2 429 LYS 429 451 451 LYS LYS B . n 
B 2 430 LYS 430 452 452 LYS LYS B . n 
B 2 431 TYR 431 453 453 TYR TYR B . n 
B 2 432 ILE 432 454 454 ILE ILE B . n 
B 2 433 LEU 433 455 455 LEU LEU B . n 
B 2 434 GLU 434 456 456 GLU GLU B . n 
B 2 435 TRP 435 457 457 TRP TRP B . n 
B 2 436 CYS 436 458 458 CYS CYS B . n 
B 2 437 VAL 437 459 459 VAL VAL B . n 
B 2 438 LEU 438 460 460 LEU LEU B . n 
B 2 439 SER 439 461 461 SER SER B . n 
B 2 440 ASP 440 462 462 ASP ASP B . n 
B 2 441 LYS 441 463 463 LYS LYS B . n 
B 2 442 ALA 442 464 464 ALA ALA B . n 
B 2 443 PRO 443 465 465 PRO PRO B . n 
B 2 444 CYS 444 466 466 CYS CYS B . n 
B 2 445 ILE 445 467 467 ILE ILE B . n 
B 2 446 THR 446 468 468 THR THR B . n 
B 2 447 ASP 447 469 469 ASP ASP B . n 
B 2 448 TRP 448 470 470 TRP TRP B . n 
B 2 449 GLN 449 471 471 GLN GLN B . n 
B 2 450 GLN 450 472 472 GLN GLN B . n 
B 2 451 GLU 451 473 473 GLU GLU B . n 
B 2 452 ASP 452 474 474 ASP ASP B . n 
B 2 453 GLY 453 475 475 GLY GLY B . n 
B 2 454 THR 454 476 476 THR THR B . n 
B 2 455 VAL 455 477 477 VAL VAL B . n 
B 2 456 HIS 456 478 478 HIS HIS B . n 
B 2 457 ARG 457 479 479 ARG ARG B . n 
B 2 458 THR 458 480 480 THR THR B . n 
B 2 459 TYR 459 481 481 TYR TYR B . n 
B 2 460 LEU 460 482 482 LEU LEU B . n 
B 2 461 ARG 461 483 483 ARG ARG B . n 
B 2 462 GLY 462 484 484 GLY GLY B . n 
B 2 463 ASN 463 485 485 ASN ASN B . n 
B 2 464 LEU 464 486 486 LEU LEU B . n 
B 2 465 ALA 465 487 487 ALA ALA B . n 
B 2 466 GLU 466 488 488 GLU GLU B . n 
B 2 467 SER 467 489 489 SER SER B . n 
B 2 468 LYS 468 490 490 LYS LYS B . n 
B 2 469 CYS 469 491 491 CYS CYS B . n 
B 2 470 TYR 470 492 492 TYR TYR B . n 
B 2 471 LEU 471 493 493 LEU LEU B . n 
B 2 472 ILE 472 494 494 ILE ILE B . n 
B 2 473 THR 473 495 495 THR THR B . n 
B 2 474 VAL 474 496 496 VAL VAL B . n 
B 2 475 THR 475 497 497 THR THR B . n 
B 2 476 PRO 476 498 498 PRO PRO B . n 
B 2 477 VAL 477 499 499 VAL VAL B . n 
B 2 478 TYR 478 500 500 TYR TYR B . n 
B 2 479 ALA 479 501 501 ALA ALA B . n 
B 2 480 ASP 480 502 502 ASP ASP B . n 
B 2 481 GLY 481 503 503 GLY GLY B . n 
B 2 482 PRO 482 504 504 PRO PRO B . n 
B 2 483 GLY 483 505 505 GLY GLY B . n 
B 2 484 SER 484 506 506 SER SER B . n 
B 2 485 PRO 485 507 507 PRO PRO B . n 
B 2 486 GLU 486 508 508 GLU GLU B . n 
B 2 487 SER 487 509 509 SER SER B . n 
B 2 488 ILE 488 510 510 ILE ILE B . n 
B 2 489 LYS 489 511 511 LYS LYS B . n 
B 2 490 ALA 490 512 512 ALA ALA B . n 
B 2 491 TYR 491 513 513 TYR TYR B . n 
B 2 492 LEU 492 514 514 LEU LEU B . n 
B 2 493 LYS 493 515 515 LYS LYS B . n 
B 2 494 GLN 494 516 516 GLN GLN B . n 
B 2 495 ALA 495 517 517 ALA ALA B . n 
B 2 496 PRO 496 518 518 PRO PRO B . n 
B 2 497 PRO 497 519 519 PRO PRO B . n 
B 2 498 SER 498 520 520 SER SER B . n 
B 2 499 LYS 499 521 521 LYS LYS B . n 
B 2 500 GLY 500 522 522 GLY GLY B . n 
B 2 501 PRO 501 523 523 PRO PRO B . n 
B 2 502 THR 502 524 524 THR THR B . n 
B 2 503 VAL 503 525 525 VAL VAL B . n 
B 2 504 ARG 504 526 526 ARG ARG B . n 
B 2 505 THR 505 527 527 THR THR B . n 
B 2 506 LYS 506 528 528 LYS LYS B . n 
B 2 507 LYS 507 529 529 LYS LYS B . n 
B 2 508 VAL 508 530 530 VAL VAL B . n 
B 2 509 GLY 509 531 531 GLY GLY B . n 
B 2 510 LYS 510 532 532 LYS LYS B . n 
B 2 511 ASN 511 533 533 ASN ASN B . n 
B 2 512 GLU 512 534 534 GLU GLU B . n 
B 2 513 ALA 513 535 535 ALA ALA B . n 
B 2 514 VAL 514 536 536 VAL VAL B . n 
B 2 515 LEU 515 537 537 LEU LEU B . n 
B 2 516 GLU 516 538 538 GLU GLU B . n 
B 2 517 TRP 517 539 539 TRP TRP B . n 
B 2 518 ASP 518 540 540 ASP ASP B . n 
B 2 519 GLN 519 541 541 GLN GLN B . n 
B 2 520 LEU 520 542 542 LEU LEU B . n 
B 2 521 PRO 521 543 543 PRO PRO B . n 
B 2 522 VAL 522 544 544 VAL VAL B . n 
B 2 523 ASP 523 545 545 ASP ASP B . n 
B 2 524 VAL 524 546 546 VAL VAL B . n 
B 2 525 GLN 525 547 547 GLN GLN B . n 
B 2 526 ASN 526 548 548 ASN ASN B . n 
B 2 527 GLY 527 549 549 GLY GLY B . n 
B 2 528 PHE 528 550 550 PHE PHE B . n 
B 2 529 ILE 529 551 551 ILE ILE B . n 
B 2 530 ARG 530 552 552 ARG ARG B . n 
B 2 531 ASN 531 553 553 ASN ASN B . n 
B 2 532 TYR 532 554 554 TYR TYR B . n 
B 2 533 THR 533 555 555 THR THR B . n 
B 2 534 ILE 534 556 556 ILE ILE B . n 
B 2 535 PHE 535 557 557 PHE PHE B . n 
B 2 536 TYR 536 558 558 TYR TYR B . n 
B 2 537 ARG 537 559 559 ARG ARG B . n 
B 2 538 THR 538 560 560 THR THR B . n 
B 2 539 ILE 539 561 561 ILE ILE B . n 
B 2 540 ILE 540 562 562 ILE ILE B . n 
B 2 541 GLY 541 563 563 GLY GLY B . n 
B 2 542 ASN 542 564 564 ASN ASN B . n 
B 2 543 GLU 543 565 565 GLU GLU B . n 
B 2 544 THR 544 566 566 THR THR B . n 
B 2 545 ALA 545 567 567 ALA ALA B . n 
B 2 546 VAL 546 568 568 VAL VAL B . n 
B 2 547 ASN 547 569 569 ASN ASN B . n 
B 2 548 VAL 548 570 570 VAL VAL B . n 
B 2 549 ASP 549 571 571 ASP ASP B . n 
B 2 550 SER 550 572 572 SER SER B . n 
B 2 551 SER 551 573 573 SER SER B . n 
B 2 552 HIS 552 574 574 HIS HIS B . n 
B 2 553 THR 553 575 575 THR THR B . n 
B 2 554 GLU 554 576 576 GLU GLU B . n 
B 2 555 TYR 555 577 577 TYR TYR B . n 
B 2 556 THR 556 578 578 THR THR B . n 
B 2 557 LEU 557 579 579 LEU LEU B . n 
B 2 558 SER 558 580 580 SER SER B . n 
B 2 559 SER 559 581 581 SER SER B . n 
B 2 560 LEU 560 582 582 LEU LEU B . n 
B 2 561 THR 561 583 583 THR THR B . n 
B 2 562 SER 562 584 584 SER SER B . n 
B 2 563 ASP 563 585 585 ASP ASP B . n 
B 2 564 THR 564 586 586 THR THR B . n 
B 2 565 LEU 565 587 587 LEU LEU B . n 
B 2 566 TYR 566 588 588 TYR TYR B . n 
B 2 567 MET 567 589 589 MET MET B . n 
B 2 568 VAL 568 590 590 VAL VAL B . n 
B 2 569 ARG 569 591 591 ARG ARG B . n 
B 2 570 MET 570 592 592 MET MET B . n 
B 2 571 ALA 571 593 593 ALA ALA B . n 
B 2 572 ALA 572 594 594 ALA ALA B . n 
B 2 573 TYR 573 595 595 TYR TYR B . n 
B 2 574 THR 574 596 596 THR THR B . n 
B 2 575 ASP 575 597 597 ASP ASP B . n 
B 2 576 GLU 576 598 598 GLU GLU B . n 
B 2 577 GLY 577 599 599 GLY GLY B . n 
B 2 578 GLY 578 600 600 GLY GLY B . n 
B 2 579 LYS 579 601 601 LYS LYS B . n 
B 2 580 ASP 580 602 602 ASP ASP B . n 
B 2 581 GLY 581 603 603 GLY GLY B . n 
B 2 582 PRO 582 604 604 PRO PRO B . n 
B 2 583 GLU 583 605 605 GLU GLU B . n 
B 2 584 PHE 584 606 606 PHE PHE B . n 
B 2 585 THR 585 607 607 THR THR B . n 
B 2 586 PHE 586 608 608 PHE PHE B . n 
B 2 587 THR 587 609 609 THR THR B . n 
B 2 588 THR 588 610 610 THR THR B . n 
B 2 589 PRO 589 611 611 PRO PRO B . n 
B 2 590 LYS 590 612 612 LYS LYS B . n 
B 2 591 PHE 591 613 ?   ?   ?   B . n 
B 2 592 ALA 592 614 ?   ?   ?   B . n 
B 2 593 GLN 593 615 ?   ?   ?   B . n 
B 2 594 GLY 594 616 ?   ?   ?   B . n 
B 2 595 GLU 595 617 ?   ?   ?   B . n 
B 2 596 ILE 596 618 ?   ?   ?   B . n 
B 2 597 GLU 597 619 ?   ?   ?   B . n 
B 2 598 GLU 598 620 ?   ?   ?   B . n 
B 2 599 GLN 599 621 ?   ?   ?   B . n 
B 2 600 LYS 600 622 ?   ?   ?   B . n 
B 2 601 LEU 601 623 ?   ?   ?   B . n 
B 2 602 ILE 602 624 ?   ?   ?   B . n 
B 2 603 SER 603 625 ?   ?   ?   B . n 
B 2 604 GLU 604 626 ?   ?   ?   B . n 
B 2 605 GLU 605 627 ?   ?   ?   B . n 
B 2 606 ASP 606 628 ?   ?   ?   B . n 
B 2 607 LEU 607 629 ?   ?   ?   B . n 
B 2 608 GLY 608 630 ?   ?   ?   B . n 
B 2 609 GLY 609 631 ?   ?   ?   B . n 
B 2 610 GLU 610 632 ?   ?   ?   B . n 
B 2 611 GLN 611 633 ?   ?   ?   B . n 
B 2 612 LYS 612 634 ?   ?   ?   B . n 
B 2 613 LEU 613 635 ?   ?   ?   B . n 
B 2 614 ILE 614 636 ?   ?   ?   B . n 
B 2 615 SER 615 637 ?   ?   ?   B . n 
B 2 616 GLU 616 638 ?   ?   ?   B . n 
B 2 617 GLU 617 639 ?   ?   ?   B . n 
B 2 618 ASP 618 640 ?   ?   ?   B . n 
B 2 619 LEU 619 641 ?   ?   ?   B . n 
B 2 620 HIS 620 642 ?   ?   ?   B . n 
B 2 621 HIS 621 643 ?   ?   ?   B . n 
B 2 622 HIS 622 644 ?   ?   ?   B . n 
B 2 623 HIS 623 645 ?   ?   ?   B . n 
B 2 624 HIS 624 646 ?   ?   ?   B . n 
B 2 625 HIS 625 647 ?   ?   ?   B . n 
C 3 1   GLN 1   45  ?   ?   ?   C . n 
C 3 2   LYS 2   46  ?   ?   ?   C . n 
C 3 3   LYS 3   47  ?   ?   ?   C . n 
C 3 4   GLY 4   48  ?   ?   ?   C . n 
C 3 5   ALA 5   49  ?   ?   ?   C . n 
C 3 6   PRO 6   50  ?   ?   ?   C . n 
C 3 7   HIS 7   51  51  HIS HIS C . n 
C 3 8   ASP 8   52  52  ASP ASP C . n 
C 3 9   LEU 9   53  53  LEU LEU C . n 
C 3 10  LYS 10  54  54  LYS LYS C . n 
C 3 11  CYS 11  55  55  CYS CYS C . n 
C 3 12  VAL 12  56  56  VAL VAL C . n 
C 3 13  THR 13  57  57  THR THR C . n 
C 3 14  ASN 14  58  58  ASN ASN C . n 
C 3 15  ASN 15  59  59  ASN ASN C . n 
C 3 16  LEU 16  60  60  LEU LEU C . n 
C 3 17  GLN 17  61  61  GLN GLN C . n 
C 3 18  VAL 18  62  62  VAL VAL C . n 
C 3 19  TRP 19  63  63  TRP TRP C . n 
C 3 20  ASN 20  64  64  ASN ASN C . n 
C 3 21  CYS 21  65  65  CYS CYS C . n 
C 3 22  SER 22  66  66  SER SER C . n 
C 3 23  TRP 23  67  67  TRP TRP C . n 
C 3 24  LYS 24  68  68  LYS LYS C . n 
C 3 25  ALA 25  69  69  ALA ALA C . n 
C 3 26  PRO 26  70  70  PRO PRO C . n 
C 3 27  SER 27  71  71  SER SER C . n 
C 3 28  GLY 28  72  72  GLY GLY C . n 
C 3 29  THR 29  73  73  THR THR C . n 
C 3 30  GLY 30  74  74  GLY GLY C . n 
C 3 31  ARG 31  75  75  ARG ARG C . n 
C 3 32  GLY 32  76  76  GLY GLY C . n 
C 3 33  THR 33  77  77  THR THR C . n 
C 3 34  ASP 34  78  78  ASP ASP C . n 
C 3 35  TYR 35  79  79  TYR TYR C . n 
C 3 36  GLU 36  80  80  GLU GLU C . n 
C 3 37  VAL 37  81  81  VAL VAL C . n 
C 3 38  CYS 38  82  82  CYS CYS C . n 
C 3 39  ILE 39  83  83  ILE ILE C . n 
C 3 40  GLU 40  84  84  GLU GLU C . n 
C 3 41  ASN 41  85  85  ASN ASN C . n 
C 3 42  ARG 42  86  86  ARG ARG C . n 
C 3 43  SER 43  87  87  SER SER C . n 
C 3 44  ARG 44  88  88  ARG ARG C . n 
C 3 45  SER 45  89  89  SER SER C . n 
C 3 46  CYS 46  90  90  CYS CYS C . n 
C 3 47  TYR 47  91  91  TYR TYR C . n 
C 3 48  GLN 48  92  92  GLN GLN C . n 
C 3 49  LEU 49  93  93  LEU LEU C . n 
C 3 50  GLU 50  94  94  GLU GLU C . n 
C 3 51  LYS 51  95  95  LYS LYS C . n 
C 3 52  THR 52  96  96  THR THR C . n 
C 3 53  SER 53  97  97  SER SER C . n 
C 3 54  ILE 54  98  98  ILE ILE C . n 
C 3 55  LYS 55  99  99  LYS LYS C . n 
C 3 56  ILE 56  100 100 ILE ILE C . n 
C 3 57  PRO 57  101 101 PRO PRO C . n 
C 3 58  ALA 58  102 102 ALA ALA C . n 
C 3 59  LEU 59  103 103 LEU LEU C . n 
C 3 60  SER 60  104 104 SER SER C . n 
C 3 61  HIS 61  105 105 HIS HIS C . n 
C 3 62  GLY 62  106 106 GLY GLY C . n 
C 3 63  ASP 63  107 107 ASP ASP C . n 
C 3 64  TYR 64  108 108 TYR TYR C . n 
C 3 65  GLU 65  109 109 GLU GLU C . n 
C 3 66  ILE 66  110 110 ILE ILE C . n 
C 3 67  THR 67  111 111 THR THR C . n 
C 3 68  ILE 68  112 112 ILE ILE C . n 
C 3 69  ASN 69  113 113 ASN ASN C . n 
C 3 70  SER 70  114 114 SER SER C . n 
C 3 71  LEU 71  115 115 LEU LEU C . n 
C 3 72  HIS 72  116 116 HIS HIS C . n 
C 3 73  ASP 73  117 117 ASP ASP C . n 
C 3 74  PHE 74  118 118 PHE PHE C . n 
C 3 75  GLY 75  119 119 GLY GLY C . n 
C 3 76  SER 76  120 120 SER SER C . n 
C 3 77  SER 77  121 121 SER SER C . n 
C 3 78  THR 78  122 122 THR THR C . n 
C 3 79  SER 79  123 123 SER SER C . n 
C 3 80  LYS 80  124 124 LYS LYS C . n 
C 3 81  PHE 81  125 125 PHE PHE C . n 
C 3 82  THR 82  126 126 THR THR C . n 
C 3 83  LEU 83  127 127 LEU LEU C . n 
C 3 84  ASN 84  128 128 ASN ASN C . n 
C 3 85  GLU 85  129 129 GLU GLU C . n 
C 3 86  GLN 86  130 130 GLN GLN C . n 
C 3 87  ASN 87  131 131 ASN ASN C . n 
C 3 88  VAL 88  132 132 VAL VAL C . n 
C 3 89  SER 89  133 133 SER SER C . n 
C 3 90  LEU 90  134 134 LEU LEU C . n 
C 3 91  ILE 91  135 135 ILE ILE C . n 
C 3 92  PRO 92  136 136 PRO PRO C . n 
C 3 93  ASP 93  137 137 ASP ASP C . n 
C 3 94  THR 94  138 138 THR THR C . n 
C 3 95  PRO 95  139 139 PRO PRO C . n 
C 3 96  GLU 96  140 140 GLU GLU C . n 
C 3 97  ILE 97  141 141 ILE ILE C . n 
C 3 98  LEU 98  142 142 LEU LEU C . n 
C 3 99  ASN 99  143 143 ASN ASN C . n 
C 3 100 LEU 100 144 144 LEU LEU C . n 
C 3 101 SER 101 145 145 SER SER C . n 
C 3 102 ALA 102 146 146 ALA ALA C . n 
C 3 103 ASP 103 147 147 ASP ASP C . n 
C 3 104 PHE 104 148 148 PHE PHE C . n 
C 3 105 SER 105 149 149 SER SER C . n 
C 3 106 THR 106 150 150 THR THR C . n 
C 3 107 SER 107 151 151 SER SER C . n 
C 3 108 THR 108 152 152 THR THR C . n 
C 3 109 LEU 109 153 153 LEU LEU C . n 
C 3 110 TYR 110 154 154 TYR TYR C . n 
C 3 111 LEU 111 155 155 LEU LEU C . n 
C 3 112 LYS 112 156 156 LYS LYS C . n 
C 3 113 TRP 113 157 157 TRP TRP C . n 
C 3 114 ASN 114 158 158 ASN ASN C . n 
C 3 115 ASP 115 159 159 ASP ASP C . n 
C 3 116 ARG 116 160 160 ARG ARG C . n 
C 3 117 GLY 117 161 161 GLY GLY C . n 
C 3 118 SER 118 162 162 SER SER C . n 
C 3 119 VAL 119 163 163 VAL VAL C . n 
C 3 120 PHE 120 164 164 PHE PHE C . n 
C 3 121 PRO 121 165 165 PRO PRO C . n 
C 3 122 HIS 122 166 166 HIS HIS C . n 
C 3 123 ARG 123 167 167 ARG ARG C . n 
C 3 124 SER 124 168 168 SER SER C . n 
C 3 125 ASN 125 169 169 ASN ASN C . n 
C 3 126 VAL 126 170 170 VAL VAL C . n 
C 3 127 ILE 127 171 171 ILE ILE C . n 
C 3 128 TRP 128 172 172 TRP TRP C . n 
C 3 129 GLU 129 173 173 GLU GLU C . n 
C 3 130 ILE 130 174 174 ILE ILE C . n 
C 3 131 LYS 131 175 175 LYS LYS C . n 
C 3 132 VAL 132 176 176 VAL VAL C . n 
C 3 133 LEU 133 177 177 LEU LEU C . n 
C 3 134 ARG 134 178 178 ARG ARG C . n 
C 3 135 LYS 135 179 179 LYS LYS C . n 
C 3 136 GLU 136 180 180 GLU GLU C . n 
C 3 137 SER 137 181 181 SER SER C . n 
C 3 138 MET 138 182 182 MET MET C . n 
C 3 139 GLU 139 183 183 GLU GLU C . n 
C 3 140 LEU 140 184 184 LEU LEU C . n 
C 3 141 VAL 141 185 185 VAL VAL C . n 
C 3 142 LYS 142 186 186 LYS LYS C . n 
C 3 143 LEU 143 187 187 LEU LEU C . n 
C 3 144 VAL 144 188 188 VAL VAL C . n 
C 3 145 THR 145 189 189 THR THR C . n 
C 3 146 HIS 146 190 190 HIS HIS C . n 
C 3 147 ASN 147 191 191 ASN ASN C . n 
C 3 148 THR 148 192 192 THR THR C . n 
C 3 149 THR 149 193 193 THR THR C . n 
C 3 150 LEU 150 194 194 LEU LEU C . n 
C 3 151 ASN 151 195 195 ASN ASN C . n 
C 3 152 GLY 152 196 196 GLY GLY C . n 
C 3 153 LYS 153 197 197 LYS LYS C . n 
C 3 154 ASP 154 198 198 ASP ASP C . n 
C 3 155 THR 155 199 199 THR THR C . n 
C 3 156 LEU 156 200 200 LEU LEU C . n 
C 3 157 HIS 157 201 201 HIS HIS C . n 
C 3 158 HIS 158 202 202 HIS HIS C . n 
C 3 159 TRP 159 203 203 TRP TRP C . n 
C 3 160 SER 160 204 204 SER SER C . n 
C 3 161 TRP 161 205 205 TRP TRP C . n 
C 3 162 ALA 162 206 206 ALA ALA C . n 
C 3 163 SER 163 207 207 SER SER C . n 
C 3 164 ASP 164 208 208 ASP ASP C . n 
C 3 165 MET 165 209 209 MET MET C . n 
C 3 166 PRO 166 210 210 PRO PRO C . n 
C 3 167 LEU 167 211 211 LEU LEU C . n 
C 3 168 GLU 168 212 212 GLU GLU C . n 
C 3 169 CYS 169 213 213 CYS CYS C . n 
C 3 170 ALA 170 214 214 ALA ALA C . n 
C 3 171 ILE 171 215 215 ILE ILE C . n 
C 3 172 HIS 172 216 216 HIS HIS C . n 
C 3 173 PHE 173 217 217 PHE PHE C . n 
C 3 174 VAL 174 218 218 VAL VAL C . n 
C 3 175 GLU 175 219 219 GLU GLU C . n 
C 3 176 ILE 176 220 220 ILE ILE C . n 
C 3 177 ARG 177 221 221 ARG ARG C . n 
C 3 178 CYS 178 222 222 CYS CYS C . n 
C 3 179 TYR 179 223 223 TYR TYR C . n 
C 3 180 ILE 180 224 224 ILE ILE C . n 
C 3 181 ASP 181 225 225 ASP ASP C . n 
C 3 182 ASN 182 226 226 ASN ASN C . n 
C 3 183 LEU 183 227 227 LEU LEU C . n 
C 3 184 HIS 184 228 228 HIS HIS C . n 
C 3 185 PHE 185 229 229 PHE PHE C . n 
C 3 186 SER 186 230 230 SER SER C . n 
C 3 187 GLY 187 231 231 GLY GLY C . n 
C 3 188 LEU 188 232 232 LEU LEU C . n 
C 3 189 GLU 189 233 233 GLU GLU C . n 
C 3 190 GLU 190 234 234 GLU GLU C . n 
C 3 191 TRP 191 235 235 TRP TRP C . n 
C 3 192 SER 192 236 236 SER SER C . n 
C 3 193 ASP 193 237 237 ASP ASP C . n 
C 3 194 TRP 194 238 238 TRP TRP C . n 
C 3 195 SER 195 239 239 SER SER C . n 
C 3 196 PRO 196 240 240 PRO PRO C . n 
C 3 197 VAL 197 241 241 VAL VAL C . n 
C 3 198 LYS 198 242 242 LYS LYS C . n 
C 3 199 ASN 199 243 243 ASN ASN C . n 
C 3 200 ILE 200 244 244 ILE ILE C . n 
C 3 201 SER 201 245 245 SER SER C . n 
C 3 202 TRP 202 246 246 TRP TRP C . n 
C 3 203 ILE 203 247 247 ILE ILE C . n 
C 3 204 PRO 204 248 248 PRO PRO C . n 
C 3 205 ASP 205 249 249 ASP ASP C . n 
C 3 206 SER 206 250 250 SER SER C . n 
C 3 207 GLN 207 251 251 GLN GLN C . n 
C 3 208 THR 208 252 252 THR THR C . n 
C 3 209 LYS 209 253 253 LYS LYS C . n 
C 3 210 VAL 210 254 254 VAL VAL C . n 
C 3 211 PHE 211 255 255 PHE PHE C . n 
C 3 212 PRO 212 256 256 PRO PRO C . n 
C 3 213 GLN 213 257 257 GLN GLN C . n 
C 3 214 ASP 214 258 258 ASP ASP C . n 
C 3 215 LYS 215 259 259 LYS LYS C . n 
C 3 216 VAL 216 260 260 VAL VAL C . n 
C 3 217 ILE 217 261 261 ILE ILE C . n 
C 3 218 LEU 218 262 262 LEU LEU C . n 
C 3 219 VAL 219 263 263 VAL VAL C . n 
C 3 220 GLY 220 264 264 GLY GLY C . n 
C 3 221 SER 221 265 265 SER SER C . n 
C 3 222 ASP 222 266 266 ASP ASP C . n 
C 3 223 ILE 223 267 267 ILE ILE C . n 
C 3 224 THR 224 268 268 THR THR C . n 
C 3 225 PHE 225 269 269 PHE PHE C . n 
C 3 226 CYS 226 270 270 CYS CYS C . n 
C 3 227 CYS 227 271 271 CYS CYS C . n 
C 3 228 VAL 228 272 272 VAL VAL C . n 
C 3 229 SER 229 273 273 SER SER C . n 
C 3 230 GLN 230 274 274 GLN GLN C . n 
C 3 231 GLU 231 275 275 GLU GLU C . n 
C 3 232 LYS 232 276 276 LYS LYS C . n 
C 3 233 VAL 233 277 277 VAL VAL C . n 
C 3 234 LEU 234 278 278 LEU LEU C . n 
C 3 235 SER 235 279 279 SER SER C . n 
C 3 236 ALA 236 280 280 ALA ALA C . n 
C 3 237 LEU 237 281 281 LEU LEU C . n 
C 3 238 ILE 238 282 282 ILE ILE C . n 
C 3 239 GLY 239 283 283 GLY GLY C . n 
C 3 240 HIS 240 284 284 HIS HIS C . n 
C 3 241 THR 241 285 285 THR THR C . n 
C 3 242 ASN 242 286 286 ASN ASN C . n 
C 3 243 CYS 243 287 287 CYS CYS C . n 
C 3 244 PRO 244 288 288 PRO PRO C . n 
C 3 245 LEU 245 289 289 LEU LEU C . n 
C 3 246 ILE 246 290 290 ILE ILE C . n 
C 3 247 HIS 247 291 291 HIS HIS C . n 
C 3 248 LEU 248 292 292 LEU LEU C . n 
C 3 249 ASP 249 293 293 ASP ASP C . n 
C 3 250 GLY 250 294 294 GLY GLY C . n 
C 3 251 GLU 251 295 295 GLU GLU C . n 
C 3 252 ASN 252 296 296 ASN ASN C . n 
C 3 253 VAL 253 297 297 VAL VAL C . n 
C 3 254 ALA 254 298 298 ALA ALA C . n 
C 3 255 ILE 255 299 299 ILE ILE C . n 
C 3 256 LYS 256 300 300 LYS LYS C . n 
C 3 257 ILE 257 301 301 ILE ILE C . n 
C 3 258 ARG 258 302 302 ARG ARG C . n 
C 3 259 ASN 259 303 303 ASN ASN C . n 
C 3 260 ILE 260 304 304 ILE ILE C . n 
C 3 261 SER 261 305 305 SER SER C . n 
C 3 262 VAL 262 306 306 VAL VAL C . n 
C 3 263 SER 263 307 307 SER SER C . n 
C 3 264 ALA 264 308 308 ALA ALA C . n 
C 3 265 SER 265 309 309 SER SER C . n 
C 3 266 SER 266 310 310 SER SER C . n 
C 3 267 GLY 267 311 311 GLY GLY C . n 
C 3 268 THR 268 312 312 THR THR C . n 
C 3 269 ASN 269 313 313 ASN ASN C . n 
C 3 270 VAL 270 314 314 VAL VAL C . n 
C 3 271 VAL 271 315 315 VAL VAL C . n 
C 3 272 PHE 272 316 316 PHE PHE C . n 
C 3 273 THR 273 317 317 THR THR C . n 
C 3 274 THR 274 318 318 THR THR C . n 
C 3 275 GLU 275 319 319 GLU GLU C . n 
C 3 276 ASP 276 320 320 ASP ASP C . n 
C 3 277 ASN 277 321 321 ASN ASN C . n 
C 3 278 ILE 278 322 322 ILE ILE C . n 
C 3 279 PHE 279 323 323 PHE PHE C . n 
C 3 280 GLY 280 324 324 GLY GLY C . n 
C 3 281 THR 281 325 325 THR THR C . n 
C 3 282 VAL 282 326 326 VAL VAL C . n 
C 3 283 ILE 283 327 327 ILE ILE C . n 
C 3 284 PHE 284 328 328 PHE PHE C . n 
C 3 285 ALA 285 329 329 ALA ALA C . n 
C 3 286 GLY 286 330 330 GLY GLY C . n 
C 3 287 TYR 287 331 331 TYR TYR C . n 
C 3 288 PRO 288 332 332 PRO PRO C . n 
C 3 289 PRO 289 333 333 PRO PRO C . n 
C 3 290 ASP 290 334 334 ASP ASP C . n 
C 3 291 THR 291 335 335 THR THR C . n 
C 3 292 PRO 292 336 336 PRO PRO C . n 
C 3 293 GLN 293 337 337 GLN GLN C . n 
C 3 294 GLN 294 338 338 GLN GLN C . n 
C 3 295 LEU 295 339 339 LEU LEU C . n 
C 3 296 ASN 296 340 340 ASN ASN C . n 
C 3 297 CYS 297 341 341 CYS CYS C . n 
C 3 298 GLU 298 342 342 GLU GLU C . n 
C 3 299 THR 299 343 343 THR THR C . n 
C 3 300 HIS 300 344 344 HIS HIS C . n 
C 3 301 ASP 301 345 345 ASP ASP C . n 
C 3 302 LEU 302 346 346 LEU LEU C . n 
C 3 303 LYS 303 347 347 LYS LYS C . n 
C 3 304 GLU 304 348 348 GLU GLU C . n 
C 3 305 ILE 305 349 349 ILE ILE C . n 
C 3 306 ILE 306 350 350 ILE ILE C . n 
C 3 307 CYS 307 351 351 CYS CYS C . n 
C 3 308 SER 308 352 352 SER SER C . n 
C 3 309 TRP 309 353 353 TRP TRP C . n 
C 3 310 ASN 310 354 354 ASN ASN C . n 
C 3 311 PRO 311 355 355 PRO PRO C . n 
C 3 312 GLY 312 356 356 GLY GLY C . n 
C 3 313 ARG 313 357 357 ARG ARG C . n 
C 3 314 VAL 314 358 358 VAL VAL C . n 
C 3 315 THR 315 359 359 THR THR C . n 
C 3 316 ALA 316 360 360 ALA ALA C . n 
C 3 317 LEU 317 361 361 LEU LEU C . n 
C 3 318 VAL 318 362 362 VAL VAL C . n 
C 3 319 GLY 319 363 363 GLY GLY C . n 
C 3 320 PRO 320 364 364 PRO PRO C . n 
C 3 321 ARG 321 365 365 ARG ARG C . n 
C 3 322 ALA 322 366 366 ALA ALA C . n 
C 3 323 THR 323 367 367 THR THR C . n 
C 3 324 SER 324 368 368 SER SER C . n 
C 3 325 TYR 325 369 369 TYR TYR C . n 
C 3 326 THR 326 370 370 THR THR C . n 
C 3 327 LEU 327 371 371 LEU LEU C . n 
C 3 328 VAL 328 372 372 VAL VAL C . n 
C 3 329 GLU 329 373 373 GLU GLU C . n 
C 3 330 SER 330 374 374 SER SER C . n 
C 3 331 PHE 331 375 375 PHE PHE C . n 
C 3 332 SER 332 376 376 SER SER C . n 
C 3 333 GLY 333 377 377 GLY GLY C . n 
C 3 334 LYS 334 378 378 LYS LYS C . n 
C 3 335 TYR 335 379 379 TYR TYR C . n 
C 3 336 VAL 336 380 380 VAL VAL C . n 
C 3 337 ARG 337 381 381 ARG ARG C . n 
C 3 338 LEU 338 382 382 LEU LEU C . n 
C 3 339 LYS 339 383 383 LYS LYS C . n 
C 3 340 ARG 340 384 384 ARG ARG C . n 
C 3 341 ALA 341 385 385 ALA ALA C . n 
C 3 342 GLU 342 386 386 GLU GLU C . n 
C 3 343 ALA 343 387 387 ALA ALA C . n 
C 3 344 PRO 344 388 388 PRO PRO C . n 
C 3 345 THR 345 389 389 THR THR C . n 
C 3 346 ASN 346 390 390 ASN ASN C . n 
C 3 347 GLU 347 391 391 GLU GLU C . n 
C 3 348 SER 348 392 392 SER SER C . n 
C 3 349 TYR 349 393 393 TYR TYR C . n 
C 3 350 GLN 350 394 394 GLN GLN C . n 
C 3 351 LEU 351 395 395 LEU LEU C . n 
C 3 352 LEU 352 396 396 LEU LEU C . n 
C 3 353 PHE 353 397 397 PHE PHE C . n 
C 3 354 GLN 354 398 398 GLN GLN C . n 
C 3 355 MET 355 399 399 MET MET C . n 
C 3 356 LEU 356 400 400 LEU LEU C . n 
C 3 357 PRO 357 401 401 PRO PRO C . n 
C 3 358 ASN 358 402 402 ASN ASN C . n 
C 3 359 GLN 359 403 403 GLN GLN C . n 
C 3 360 GLU 360 404 404 GLU GLU C . n 
C 3 361 ILE 361 405 405 ILE ILE C . n 
C 3 362 TYR 362 406 406 TYR TYR C . n 
C 3 363 ASN 363 407 407 ASN ASN C . n 
C 3 364 PHE 364 408 408 PHE PHE C . n 
C 3 365 THR 365 409 409 THR THR C . n 
C 3 366 LEU 366 410 410 LEU LEU C . n 
C 3 367 ASN 367 411 411 ASN ASN C . n 
C 3 368 ALA 368 412 412 ALA ALA C . n 
C 3 369 HIS 369 413 413 HIS HIS C . n 
C 3 370 ASN 370 414 414 ASN ASN C . n 
C 3 371 PRO 371 415 415 PRO PRO C . n 
C 3 372 LEU 372 416 416 LEU LEU C . n 
C 3 373 GLY 373 417 417 GLY GLY C . n 
C 3 374 ARG 374 418 418 ARG ARG C . n 
C 3 375 SER 375 419 419 SER SER C . n 
C 3 376 GLN 376 420 420 GLN GLN C . n 
C 3 377 SER 377 421 421 SER SER C . n 
C 3 378 THR 378 422 422 THR THR C . n 
C 3 379 ILE 379 423 423 ILE ILE C . n 
C 3 380 LEU 380 424 424 LEU LEU C . n 
C 3 381 VAL 381 425 425 VAL VAL C . n 
C 3 382 ASN 382 426 426 ASN ASN C . n 
C 3 383 ILE 383 427 427 ILE ILE C . n 
C 3 384 THR 384 428 428 THR THR C . n 
C 3 385 GLU 385 429 429 GLU GLU C . n 
C 3 386 LYS 386 430 430 LYS LYS C . n 
C 3 387 VAL 387 431 431 VAL VAL C . n 
C 3 388 TYR 388 432 432 TYR TYR C . n 
C 3 389 PRO 389 433 433 PRO PRO C . n 
C 3 390 HIS 390 434 434 HIS HIS C . n 
C 3 391 THR 391 435 435 THR THR C . n 
C 3 392 PRO 392 436 436 PRO PRO C . n 
C 3 393 THR 393 437 437 THR THR C . n 
C 3 394 SER 394 438 438 SER SER C . n 
C 3 395 PHE 395 439 439 PHE PHE C . n 
C 3 396 LYS 396 440 440 LYS LYS C . n 
C 3 397 VAL 397 441 441 VAL VAL C . n 
C 3 398 LYS 398 442 442 LYS LYS C . n 
C 3 399 ASP 399 443 443 ASP ASP C . n 
C 3 400 ILE 400 444 444 ILE ILE C . n 
C 3 401 ASN 401 445 445 ASN ASN C . n 
C 3 402 SER 402 446 446 SER SER C . n 
C 3 403 THR 403 447 447 THR THR C . n 
C 3 404 ALA 404 448 448 ALA ALA C . n 
C 3 405 VAL 405 449 449 VAL VAL C . n 
C 3 406 LYS 406 450 450 LYS LYS C . n 
C 3 407 LEU 407 451 451 LEU LEU C . n 
C 3 408 SER 408 452 452 SER SER C . n 
C 3 409 TRP 409 453 453 TRP TRP C . n 
C 3 410 HIS 410 454 454 HIS HIS C . n 
C 3 411 LEU 411 455 455 LEU LEU C . n 
C 3 412 PRO 412 456 456 PRO PRO C . n 
C 3 413 GLY 413 457 457 GLY GLY C . n 
C 3 414 ASN 414 458 458 ASN ASN C . n 
C 3 415 PHE 415 459 459 PHE PHE C . n 
C 3 416 ALA 416 460 460 ALA ALA C . n 
C 3 417 LYS 417 461 461 LYS LYS C . n 
C 3 418 ILE 418 462 462 ILE ILE C . n 
C 3 419 ASN 419 463 463 ASN ASN C . n 
C 3 420 PHE 420 464 464 PHE PHE C . n 
C 3 421 LEU 421 465 465 LEU LEU C . n 
C 3 422 CYS 422 466 466 CYS CYS C . n 
C 3 423 GLU 423 467 467 GLU GLU C . n 
C 3 424 ILE 424 468 468 ILE ILE C . n 
C 3 425 GLU 425 469 469 GLU GLU C . n 
C 3 426 ILE 426 470 470 ILE ILE C . n 
C 3 427 LYS 427 471 471 LYS LYS C . n 
C 3 428 LYS 428 472 472 LYS LYS C . n 
C 3 429 SER 429 473 473 SER SER C . n 
C 3 430 ASN 430 474 474 ASN ASN C . n 
C 3 431 SER 431 475 475 SER SER C . n 
C 3 432 VAL 432 476 476 VAL VAL C . n 
C 3 433 GLN 433 477 477 GLN GLN C . n 
C 3 434 GLU 434 478 478 GLU GLU C . n 
C 3 435 GLN 435 479 479 GLN GLN C . n 
C 3 436 ARG 436 480 480 ARG ARG C . n 
C 3 437 ASN 437 481 481 ASN ASN C . n 
C 3 438 VAL 438 482 482 VAL VAL C . n 
C 3 439 THR 439 483 483 THR THR C . n 
C 3 440 ILE 440 484 484 ILE ILE C . n 
C 3 441 LYS 441 485 485 LYS LYS C . n 
C 3 442 GLY 442 486 486 GLY GLY C . n 
C 3 443 VAL 443 487 487 VAL VAL C . n 
C 3 444 GLU 444 488 488 GLU GLU C . n 
C 3 445 ASN 445 489 489 ASN ASN C . n 
C 3 446 SER 446 490 490 SER SER C . n 
C 3 447 SER 447 491 491 SER SER C . n 
C 3 448 TYR 448 492 492 TYR TYR C . n 
C 3 449 LEU 449 493 493 LEU LEU C . n 
C 3 450 VAL 450 494 494 VAL VAL C . n 
C 3 451 ALA 451 495 495 ALA ALA C . n 
C 3 452 LEU 452 496 496 LEU LEU C . n 
C 3 453 ASP 453 497 497 ASP ASP C . n 
C 3 454 LYS 454 498 498 LYS LYS C . n 
C 3 455 LEU 455 499 499 LEU LEU C . n 
C 3 456 ASN 456 500 500 ASN ASN C . n 
C 3 457 PRO 457 501 501 PRO PRO C . n 
C 3 458 TYR 458 502 502 TYR TYR C . n 
C 3 459 THR 459 503 503 THR THR C . n 
C 3 460 LEU 460 504 504 LEU LEU C . n 
C 3 461 TYR 461 505 505 TYR TYR C . n 
C 3 462 THR 462 506 506 THR THR C . n 
C 3 463 PHE 463 507 507 PHE PHE C . n 
C 3 464 ARG 464 508 508 ARG ARG C . n 
C 3 465 ILE 465 509 509 ILE ILE C . n 
C 3 466 ARG 466 510 510 ARG ARG C . n 
C 3 467 CYS 467 511 511 CYS CYS C . n 
C 3 468 SER 468 512 512 SER SER C . n 
C 3 469 THR 469 513 513 THR THR C . n 
C 3 470 GLU 470 514 514 GLU GLU C . n 
C 3 471 THR 471 515 515 THR THR C . n 
C 3 472 PHE 472 516 516 PHE PHE C . n 
C 3 473 TRP 473 517 517 TRP TRP C . n 
C 3 474 LYS 474 518 518 LYS LYS C . n 
C 3 475 TRP 475 519 519 TRP TRP C . n 
C 3 476 SER 476 520 520 SER SER C . n 
C 3 477 LYS 477 521 521 LYS LYS C . n 
C 3 478 TRP 478 522 522 TRP TRP C . n 
C 3 479 SER 479 523 523 SER SER C . n 
C 3 480 ASN 480 524 524 ASN ASN C . n 
C 3 481 LYS 481 525 525 LYS LYS C . n 
C 3 482 LYS 482 526 526 LYS LYS C . n 
C 3 483 GLN 483 527 527 GLN GLN C . n 
C 3 484 HIS 484 528 528 HIS HIS C . n 
C 3 485 LEU 485 529 529 LEU LEU C . n 
C 3 486 THR 486 530 530 THR THR C . n 
C 3 487 THR 487 531 531 THR THR C . n 
C 3 488 GLU 488 532 532 GLU GLU C . n 
C 3 489 ALA 489 533 533 ALA ALA C . n 
C 3 490 SER 490 534 534 SER SER C . n 
C 3 491 PRO 491 535 535 PRO PRO C . n 
C 3 492 SER 492 536 536 SER SER C . n 
C 3 493 LYS 493 537 537 LYS LYS C . n 
C 3 494 GLY 494 538 538 GLY GLY C . n 
C 3 495 PRO 495 539 539 PRO PRO C . n 
C 3 496 ASP 496 540 540 ASP ASP C . n 
C 3 497 THR 497 541 541 THR THR C . n 
C 3 498 TRP 498 542 542 TRP TRP C . n 
C 3 499 ARG 499 543 543 ARG ARG C . n 
C 3 500 GLU 500 544 544 GLU GLU C . n 
C 3 501 TRP 501 545 545 TRP TRP C . n 
C 3 502 SER 502 546 546 SER SER C . n 
C 3 503 SER 503 547 547 SER SER C . n 
C 3 504 ASP 504 548 548 ASP ASP C . n 
C 3 505 GLY 505 549 549 GLY GLY C . n 
C 3 506 LYS 506 550 550 LYS LYS C . n 
C 3 507 ASN 507 551 551 ASN ASN C . n 
C 3 508 LEU 508 552 552 LEU LEU C . n 
C 3 509 ILE 509 553 553 ILE ILE C . n 
C 3 510 ILE 510 554 554 ILE ILE C . n 
C 3 511 TYR 511 555 555 TYR TYR C . n 
C 3 512 TRP 512 556 556 TRP TRP C . n 
C 3 513 LYS 513 557 557 LYS LYS C . n 
C 3 514 PRO 514 558 558 PRO PRO C . n 
C 3 515 LEU 515 559 559 LEU LEU C . n 
C 3 516 PRO 516 560 560 PRO PRO C . n 
C 3 517 ILE 517 561 561 ILE ILE C . n 
C 3 518 ASN 518 562 562 ASN ASN C . n 
C 3 519 GLU 519 563 563 GLU GLU C . n 
C 3 520 ALA 520 564 564 ALA ALA C . n 
C 3 521 ASN 521 565 565 ASN ASN C . n 
C 3 522 GLY 522 566 566 GLY GLY C . n 
C 3 523 LYS 523 567 567 LYS LYS C . n 
C 3 524 ILE 524 568 568 ILE ILE C . n 
C 3 525 LEU 525 569 569 LEU LEU C . n 
C 3 526 SER 526 570 570 SER SER C . n 
C 3 527 TYR 527 571 571 TYR TYR C . n 
C 3 528 ASN 528 572 572 ASN ASN C . n 
C 3 529 VAL 529 573 573 VAL VAL C . n 
C 3 530 SER 530 574 574 SER SER C . n 
C 3 531 CYS 531 575 575 CYS CYS C . n 
C 3 532 SER 532 576 576 SER SER C . n 
C 3 533 SER 533 577 577 SER SER C . n 
C 3 534 ASP 534 578 578 ASP ASP C . n 
C 3 535 GLU 535 579 579 GLU GLU C . n 
C 3 536 GLU 536 580 580 GLU GLU C . n 
C 3 537 THR 537 581 581 THR THR C . n 
C 3 538 GLN 538 582 582 GLN GLN C . n 
C 3 539 SER 539 583 583 SER SER C . n 
C 3 540 LEU 540 584 584 LEU LEU C . n 
C 3 541 SER 541 585 585 SER SER C . n 
C 3 542 GLU 542 586 586 GLU GLU C . n 
C 3 543 ILE 543 587 587 ILE ILE C . n 
C 3 544 PRO 544 588 588 PRO PRO C . n 
C 3 545 ASP 545 589 589 ASP ASP C . n 
C 3 546 PRO 546 590 590 PRO PRO C . n 
C 3 547 GLN 547 591 591 GLN GLN C . n 
C 3 548 HIS 548 592 592 HIS HIS C . n 
C 3 549 LYS 549 593 593 LYS LYS C . n 
C 3 550 ALA 550 594 594 ALA ALA C . n 
C 3 551 GLU 551 595 595 GLU GLU C . n 
C 3 552 ILE 552 596 596 ILE ILE C . n 
C 3 553 ARG 553 597 597 ARG ARG C . n 
C 3 554 LEU 554 598 598 LEU LEU C . n 
C 3 555 ASP 555 599 599 ASP ASP C . n 
C 3 556 LYS 556 600 600 LYS LYS C . n 
C 3 557 ASN 557 601 601 ASN ASN C . n 
C 3 558 ASP 558 602 602 ASP ASP C . n 
C 3 559 TYR 559 603 603 TYR TYR C . n 
C 3 560 ILE 560 604 604 ILE ILE C . n 
C 3 561 ILE 561 605 605 ILE ILE C . n 
C 3 562 SER 562 606 606 SER SER C . n 
C 3 563 VAL 563 607 607 VAL VAL C . n 
C 3 564 VAL 564 608 608 VAL VAL C . n 
C 3 565 ALA 565 609 609 ALA ALA C . n 
C 3 566 LYS 566 610 610 LYS LYS C . n 
C 3 567 ASN 567 611 611 ASN ASN C . n 
C 3 568 SER 568 612 612 SER SER C . n 
C 3 569 VAL 569 613 613 VAL VAL C . n 
C 3 570 GLY 570 614 614 GLY GLY C . n 
C 3 571 SER 571 615 615 SER SER C . n 
C 3 572 SER 572 616 616 SER SER C . n 
C 3 573 PRO 573 617 617 PRO PRO C . n 
C 3 574 PRO 574 618 618 PRO PRO C . n 
C 3 575 SER 575 619 619 SER SER C . n 
C 3 576 LYS 576 620 620 LYS LYS C . n 
C 3 577 ILE 577 621 621 ILE ILE C . n 
C 3 578 ALA 578 622 622 ALA ALA C . n 
C 3 579 SER 579 623 623 SER SER C . n 
C 3 580 MET 580 624 624 MET MET C . n 
C 3 581 GLU 581 625 625 GLU GLU C . n 
C 3 582 ILE 582 626 626 ILE ILE C . n 
C 3 583 PRO 583 627 627 PRO PRO C . n 
C 3 584 ASN 584 628 628 ASN ASN C . n 
C 3 585 ASP 585 629 629 ASP ASP C . n 
C 3 586 ASP 586 630 630 ASP ASP C . n 
C 3 587 LEU 587 631 631 LEU LEU C . n 
C 3 588 LYS 588 632 632 LYS LYS C . n 
C 3 589 ILE 589 633 633 ILE ILE C . n 
C 3 590 GLU 590 634 634 GLU GLU C . n 
C 3 591 GLN 591 635 635 GLN GLN C . n 
C 3 592 VAL 592 636 636 VAL VAL C . n 
C 3 593 VAL 593 637 637 VAL VAL C . n 
C 3 594 GLY 594 638 638 GLY GLY C . n 
C 3 595 MET 595 639 639 MET MET C . n 
C 3 596 GLY 596 640 640 GLY GLY C . n 
C 3 597 LYS 597 641 641 LYS LYS C . n 
C 3 598 GLY 598 642 642 GLY GLY C . n 
C 3 599 ILE 599 643 643 ILE ILE C . n 
C 3 600 LEU 600 644 644 LEU LEU C . n 
C 3 601 LEU 601 645 645 LEU LEU C . n 
C 3 602 THR 602 646 646 THR THR C . n 
C 3 603 TRP 603 647 647 TRP TRP C . n 
C 3 604 HIS 604 648 648 HIS HIS C . n 
C 3 605 TYR 605 649 649 TYR TYR C . n 
C 3 606 ASP 606 650 650 ASP ASP C . n 
C 3 607 PRO 607 651 651 PRO PRO C . n 
C 3 608 ASN 608 652 652 ASN ASN C . n 
C 3 609 MET 609 653 653 MET MET C . n 
C 3 610 THR 610 654 654 THR THR C . n 
C 3 611 CYS 611 655 655 CYS CYS C . n 
C 3 612 ASP 612 656 656 ASP ASP C . n 
C 3 613 TYR 613 657 657 TYR TYR C . n 
C 3 614 VAL 614 658 658 VAL VAL C . n 
C 3 615 ILE 615 659 659 ILE ILE C . n 
C 3 616 LYS 616 660 660 LYS LYS C . n 
C 3 617 TRP 617 661 661 TRP TRP C . n 
C 3 618 CYS 618 662 662 CYS CYS C . n 
C 3 619 ASN 619 663 663 ASN ASN C . n 
C 3 620 SER 620 664 664 SER SER C . n 
C 3 621 SER 621 665 665 SER SER C . n 
C 3 622 ARG 622 666 666 ARG ARG C . n 
C 3 623 SER 623 667 667 SER SER C . n 
C 3 624 GLU 624 668 668 GLU GLU C . n 
C 3 625 PRO 625 669 669 PRO PRO C . n 
C 3 626 CYS 626 670 670 CYS CYS C . n 
C 3 627 LEU 627 671 671 LEU LEU C . n 
C 3 628 MET 628 672 672 MET MET C . n 
C 3 629 ASP 629 673 673 ASP ASP C . n 
C 3 630 TRP 630 674 674 TRP TRP C . n 
C 3 631 ARG 631 675 675 ARG ARG C . n 
C 3 632 LYS 632 676 676 LYS LYS C . n 
C 3 633 VAL 633 677 677 VAL VAL C . n 
C 3 634 PRO 634 678 678 PRO PRO C . n 
C 3 635 SER 635 679 679 SER SER C . n 
C 3 636 ASN 636 680 680 ASN ASN C . n 
C 3 637 SER 637 681 681 SER SER C . n 
C 3 638 THR 638 682 682 THR THR C . n 
C 3 639 GLU 639 683 683 GLU GLU C . n 
C 3 640 THR 640 684 684 THR THR C . n 
C 3 641 VAL 641 685 685 VAL VAL C . n 
C 3 642 ILE 642 686 686 ILE ILE C . n 
C 3 643 GLU 643 687 687 GLU GLU C . n 
C 3 644 SER 644 688 688 SER SER C . n 
C 3 645 ASP 645 689 689 ASP ASP C . n 
C 3 646 GLU 646 690 690 GLU GLU C . n 
C 3 647 PHE 647 691 691 PHE PHE C . n 
C 3 648 ARG 648 692 692 ARG ARG C . n 
C 3 649 PRO 649 693 693 PRO PRO C . n 
C 3 650 GLY 650 694 694 GLY GLY C . n 
C 3 651 ILE 651 695 695 ILE ILE C . n 
C 3 652 ARG 652 696 696 ARG ARG C . n 
C 3 653 TYR 653 697 697 TYR TYR C . n 
C 3 654 ASN 654 698 698 ASN ASN C . n 
C 3 655 PHE 655 699 699 PHE PHE C . n 
C 3 656 PHE 656 700 700 PHE PHE C . n 
C 3 657 LEU 657 701 701 LEU LEU C . n 
C 3 658 TYR 658 702 702 TYR TYR C . n 
C 3 659 GLY 659 703 703 GLY GLY C . n 
C 3 660 CYS 660 704 704 CYS CYS C . n 
C 3 661 ARG 661 705 705 ARG ARG C . n 
C 3 662 ASN 662 706 706 ASN ASN C . n 
C 3 663 GLN 663 707 707 GLN GLN C . n 
C 3 664 GLY 664 708 708 GLY GLY C . n 
C 3 665 TYR 665 709 709 TYR TYR C . n 
C 3 666 GLN 666 710 710 GLN GLN C . n 
C 3 667 LEU 667 711 711 LEU LEU C . n 
C 3 668 LEU 668 712 712 LEU LEU C . n 
C 3 669 ARG 669 713 713 ARG ARG C . n 
C 3 670 SER 670 714 714 SER SER C . n 
C 3 671 MET 671 715 715 MET MET C . n 
C 3 672 ILE 672 716 716 ILE ILE C . n 
C 3 673 GLY 673 717 717 GLY GLY C . n 
C 3 674 TYR 674 718 718 TYR TYR C . n 
C 3 675 ILE 675 719 719 ILE ILE C . n 
C 3 676 GLU 676 720 720 GLU GLU C . n 
C 3 677 GLU 677 721 721 GLU GLU C . n 
C 3 678 LEU 678 722 722 LEU LEU C . n 
C 3 679 ALA 679 723 723 ALA ALA C . n 
C 3 680 PRO 680 724 724 PRO PRO C . n 
C 3 681 ILE 681 725 725 ILE ILE C . n 
C 3 682 VAL 682 726 726 VAL VAL C . n 
C 3 683 ALA 683 727 727 ALA ALA C . n 
C 3 684 PRO 684 728 728 PRO PRO C . n 
C 3 685 ASN 685 729 729 ASN ASN C . n 
C 3 686 PHE 686 730 730 PHE PHE C . n 
C 3 687 THR 687 731 731 THR THR C . n 
C 3 688 VAL 688 732 732 VAL VAL C . n 
C 3 689 GLU 689 733 733 GLU GLU C . n 
C 3 690 ASP 690 734 734 ASP ASP C . n 
C 3 691 THR 691 735 735 THR THR C . n 
C 3 692 SER 692 736 736 SER SER C . n 
C 3 693 ALA 693 737 737 ALA ALA C . n 
C 3 694 ASP 694 738 738 ASP ASP C . n 
C 3 695 SER 695 739 739 SER SER C . n 
C 3 696 ILE 696 740 740 ILE ILE C . n 
C 3 697 LEU 697 741 741 LEU LEU C . n 
C 3 698 VAL 698 742 742 VAL VAL C . n 
C 3 699 LYS 699 743 743 LYS LYS C . n 
C 3 700 TRP 700 744 744 TRP TRP C . n 
C 3 701 GLU 701 745 745 GLU GLU C . n 
C 3 702 ASP 702 746 746 ASP ASP C . n 
C 3 703 ILE 703 747 747 ILE ILE C . n 
C 3 704 PRO 704 748 748 PRO PRO C . n 
C 3 705 VAL 705 749 749 VAL VAL C . n 
C 3 706 GLU 706 750 750 GLU GLU C . n 
C 3 707 GLU 707 751 751 GLU GLU C . n 
C 3 708 LEU 708 752 752 LEU LEU C . n 
C 3 709 ARG 709 753 753 ARG ARG C . n 
C 3 710 GLY 710 754 754 GLY GLY C . n 
C 3 711 PHE 711 755 755 PHE PHE C . n 
C 3 712 LEU 712 756 756 LEU LEU C . n 
C 3 713 ARG 713 757 757 ARG ARG C . n 
C 3 714 GLY 714 758 758 GLY GLY C . n 
C 3 715 TYR 715 759 759 TYR TYR C . n 
C 3 716 LEU 716 760 760 LEU LEU C . n 
C 3 717 PHE 717 761 761 PHE PHE C . n 
C 3 718 TYR 718 762 762 TYR TYR C . n 
C 3 719 PHE 719 763 763 PHE PHE C . n 
C 3 720 GLY 720 764 764 GLY GLY C . n 
C 3 721 LYS 721 765 765 LYS LYS C . n 
C 3 722 GLY 722 766 766 GLY GLY C . n 
C 3 723 GLU 723 767 ?   ?   ?   C . n 
C 3 724 ARG 724 768 ?   ?   ?   C . n 
C 3 725 ASP 725 769 ?   ?   ?   C . n 
C 3 726 THR 726 770 ?   ?   ?   C . n 
C 3 727 SER 727 771 ?   ?   ?   C . n 
C 3 728 LYS 728 772 ?   ?   ?   C . n 
C 3 729 MET 729 773 ?   ?   ?   C . n 
C 3 730 ARG 730 774 ?   ?   ?   C . n 
C 3 731 VAL 731 775 ?   ?   ?   C . n 
C 3 732 LEU 732 776 ?   ?   ?   C . n 
C 3 733 GLU 733 777 ?   ?   ?   C . n 
C 3 734 SER 734 778 ?   ?   ?   C . n 
C 3 735 GLY 735 779 ?   ?   ?   C . n 
C 3 736 ARG 736 780 ?   ?   ?   C . n 
C 3 737 SER 737 781 ?   ?   ?   C . n 
C 3 738 ASP 738 782 782 ASP ASP C . n 
C 3 739 ILE 739 783 783 ILE ILE C . n 
C 3 740 LYS 740 784 784 LYS LYS C . n 
C 3 741 VAL 741 785 785 VAL VAL C . n 
C 3 742 LYS 742 786 786 LYS LYS C . n 
C 3 743 ASN 743 787 787 ASN ASN C . n 
C 3 744 ILE 744 788 788 ILE ILE C . n 
C 3 745 THR 745 789 789 THR THR C . n 
C 3 746 ASP 746 790 790 ASP ASP C . n 
C 3 747 ILE 747 791 791 ILE ILE C . n 
C 3 748 SER 748 792 792 SER SER C . n 
C 3 749 GLN 749 793 793 GLN GLN C . n 
C 3 750 LYS 750 794 794 LYS LYS C . n 
C 3 751 THR 751 795 795 THR THR C . n 
C 3 752 LEU 752 796 796 LEU LEU C . n 
C 3 753 ARG 753 797 797 ARG ARG C . n 
C 3 754 ILE 754 798 798 ILE ILE C . n 
C 3 755 ALA 755 799 799 ALA ALA C . n 
C 3 756 ASP 756 800 800 ASP ASP C . n 
C 3 757 LEU 757 801 801 LEU LEU C . n 
C 3 758 GLN 758 802 802 GLN GLN C . n 
C 3 759 GLY 759 803 803 GLY GLY C . n 
C 3 760 LYS 760 804 804 LYS LYS C . n 
C 3 761 THR 761 805 805 THR THR C . n 
C 3 762 SER 762 806 806 SER SER C . n 
C 3 763 TYR 763 807 807 TYR TYR C . n 
C 3 764 HIS 764 808 808 HIS HIS C . n 
C 3 765 LEU 765 809 809 LEU LEU C . n 
C 3 766 VAL 766 810 810 VAL VAL C . n 
C 3 767 LEU 767 811 811 LEU LEU C . n 
C 3 768 ARG 768 812 812 ARG ARG C . n 
C 3 769 ALA 769 813 813 ALA ALA C . n 
C 3 770 TYR 770 814 814 TYR TYR C . n 
C 3 771 THR 771 815 815 THR THR C . n 
C 3 772 ASP 772 816 816 ASP ASP C . n 
C 3 773 GLY 773 817 817 GLY GLY C . n 
C 3 774 GLY 774 818 818 GLY GLY C . n 
C 3 775 VAL 775 819 819 VAL VAL C . n 
C 3 776 GLY 776 820 820 GLY GLY C . n 
C 3 777 PRO 777 821 821 PRO PRO C . n 
C 3 778 GLU 778 822 822 GLU GLU C . n 
C 3 779 LYS 779 823 823 LYS LYS C . n 
C 3 780 SER 780 824 824 SER SER C . n 
C 3 781 MET 781 825 825 MET MET C . n 
C 3 782 TYR 782 826 826 TYR TYR C . n 
C 3 783 VAL 783 827 827 VAL VAL C . n 
C 3 784 VAL 784 828 828 VAL VAL C . n 
C 3 785 THR 785 829 829 THR THR C . n 
C 3 786 LYS 786 830 830 LYS LYS C . n 
C 3 787 GLU 787 831 831 GLU GLU C . n 
C 3 788 ASN 788 832 ?   ?   ?   C . n 
C 3 789 SER 789 833 ?   ?   ?   C . n 
C 3 790 GLU 790 834 ?   ?   ?   C . n 
C 3 791 GLN 791 835 ?   ?   ?   C . n 
C 3 792 LYS 792 836 ?   ?   ?   C . n 
C 3 793 LEU 793 837 ?   ?   ?   C . n 
C 3 794 ILE 794 838 ?   ?   ?   C . n 
C 3 795 SER 795 839 ?   ?   ?   C . n 
C 3 796 GLU 796 840 ?   ?   ?   C . n 
C 3 797 GLU 797 841 ?   ?   ?   C . n 
C 3 798 ASP 798 842 ?   ?   ?   C . n 
C 3 799 LEU 799 843 ?   ?   ?   C . n 
C 3 800 GLY 800 844 ?   ?   ?   C . n 
C 3 801 GLY 801 845 ?   ?   ?   C . n 
C 3 802 GLU 802 846 ?   ?   ?   C . n 
C 3 803 GLN 803 847 ?   ?   ?   C . n 
C 3 804 LYS 804 848 ?   ?   ?   C . n 
C 3 805 LEU 805 849 ?   ?   ?   C . n 
C 3 806 ILE 806 850 ?   ?   ?   C . n 
C 3 807 SER 807 851 ?   ?   ?   C . n 
C 3 808 GLU 808 852 ?   ?   ?   C . n 
C 3 809 GLU 809 853 ?   ?   ?   C . n 
C 3 810 ASP 810 854 ?   ?   ?   C . n 
C 3 811 LEU 811 855 ?   ?   ?   C . n 
C 3 812 HIS 812 856 ?   ?   ?   C . n 
C 3 813 HIS 813 857 ?   ?   ?   C . n 
C 3 814 HIS 814 858 ?   ?   ?   C . n 
C 3 815 HIS 815 859 ?   ?   ?   C . n 
C 3 816 HIS 816 860 ?   ?   ?   C . n 
C 3 817 HIS 817 861 ?   ?   ?   C . n 
# 
loop_
_pdbx_branch_scheme.asym_id 
_pdbx_branch_scheme.entity_id 
_pdbx_branch_scheme.mon_id 
_pdbx_branch_scheme.num 
_pdbx_branch_scheme.pdb_asym_id 
_pdbx_branch_scheme.pdb_mon_id 
_pdbx_branch_scheme.pdb_seq_num 
_pdbx_branch_scheme.auth_asym_id 
_pdbx_branch_scheme.auth_mon_id 
_pdbx_branch_scheme.auth_seq_num 
_pdbx_branch_scheme.hetero 
D 4 NAG 1 D NAG 1 A NAG 1104 n 
D 4 NAG 2 D NAG 2 A NAG 1105 n 
E 4 NAG 1 E NAG 1 B NAG 1005 n 
E 4 NAG 2 E NAG 2 B NAG 1006 n 
F 4 NAG 1 F NAG 1 C NAG 1104 n 
F 4 NAG 2 F NAG 2 C NAG 1105 n 
G 4 NAG 1 G NAG 1 C NAG 1108 n 
G 4 NAG 2 G NAG 2 C NAG 1109 n 
H 4 NAG 1 H NAG 1 C NAG 1113 n 
H 4 NAG 2 H NAG 2 C NAG 1114 n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
I 5 NAG 1 701 991  NAG NAG B . 
J 5 NAG 1 702 992  NAG NAG B . 
K 5 NAG 1 703 993  NAG NAG B . 
L 5 NAG 1 704 1001 NAG NAG B . 
M 5 NAG 1 705 1004 NAG NAG B . 
N 5 NAG 1 706 1007 NAG NAG B . 
O 5 NAG 1 901 1110 NAG NAG C . 
P 5 NAG 1 902 1115 NAG NAG C . 
Q 5 NAG 1 903 1116 NAG NAG C . 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8V29 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8V29 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8V29 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.entry_id                                 8V29 
_refine.pdbx_diffrn_id                           ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             ? 
_refine.ls_d_res_high                            . 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.B_iso_mean                               ? 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_ksol                 ? 
_refine.solvent_model_param_bsol                 ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.details                                  ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.002  ? 12758 ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.391  ? 17349 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 16.522 ? 1759  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.040  ? 1991  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.003  ? 2182  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     8V29 
_struct.title                        
'Cryo-EM structure of human type I OSM receptor complex: model for full extracellular assembly' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8V29 
_struct_keywords.text            'cytokine signaling, OSM, gp130, LIFR, CYTOKINE, CYTOKINE-RECEPTOR complex' 
_struct_keywords.pdbx_keywords   CYTOKINE/RECEPTOR 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
E N N 4 ? 
F N N 4 ? 
G N N 4 ? 
H N N 4 ? 
I N N 5 ? 
J N N 5 ? 
K N N 5 ? 
L N N 5 ? 
M N N 5 ? 
N N N 5 ? 
O N N 5 ? 
P N N 5 ? 
Q N N 5 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP ONCM_HUMAN  P13725 ? 1 
;AAIGSCSKEYRVLLGQLQKQTDLMQDTSRLLDPYIRIQGLDVPKLREHCRERPGAFPSEETLRGLGRRGFLQTLNATLGC
VLHRLADLEQRLPKAQDLERSGLNIEDLEKLQMARPNILGLRNNIYCMAQLLDNSDTAEPTKAGRGASQPPTPTPASDAF
QRKLEGCRFLHGYHRFMHSVGRVFSKWGESPNRSRR
;
26 
2 UNP IL6RB_HUMAN P40189 ? 2 
;ELLDPCGYISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLT
CNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSC
TVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYR
TKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQ
GYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQ
ATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYAD
GPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSL
TSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIE
;
23 
3 UNP LIFR_HUMAN  P42702 ? 3 
;QKKGAPHDLKCVTNNLQVWNCSWKAPSGTGRGTDYEVCIENRSRSCYQLEKTSIKIPALSHGDYEITINSLHDFGSSTSK
FTLNEQNVSLIPDTPEILNLSADFSTSTLYLKWNDRGSVFPHRSNVIWEIKVLRKESMELVKLVTHNTTLNGKDTLHHWS
WASDMPLECAIHFVEIRCYIDNLHFSGLEEWSDWSPVKNISWIPDSQTKVFPQDKVILVGSDITFCCVSQEKVLSALIGH
TNCPLIHLDGENVAIKIRNISVSASSGTNVVFTTEDNIFGTVIFAGYPPDTPQQLNCETHDLKEIICSWNPGRVTALVGP
RATSYTLVESFSGKYVRLKRAEAPTNESYQLLFQMLPNQEIYNFTLNAHNPLGRSQSTILVNITEKVYPHTPTSFKVKDI
NSTAVKLSWHLPGNFAKINFLCEIEIKKSNSVQEQRNVTIKGVENSSYLVALDKLNPYTLYTFRIRCSTETFWKWSKWSN
KKQHLTTEASPSKGPDTWREWSSDGKNLIIYWKPLPINEANGKILSYNVSCSSDEETQSLSEIPDPQHKAEIRLDKNDYI
ISVVAKNSVGSSPPSKIASMEIPNDDLKIEQVVGMGKGILLTWHYDPNMTCDYVIKWCNSSRSEPCLMDWRKVPSNSTET
VIESDEFRPGIRYNFFLYGCRNQGYQLLRSMIGYIEELAPIVAPNFTVEDTSADSILVKWEDIPVEELRGFLRGYLFYFG
KGERDTSKMRVLESGRSDIKVKNITDISQKTLRIADLQGKTSYHLVLRAYTDGGVGPEKSMYVVTKENS
;
45 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8V29 A 1 ? 196 ? P13725 26 ? 221 ? 26 221 
2 2 8V29 B 1 ? 597 ? P40189 23 ? 619 ? 23 619 
3 3 8V29 C 1 ? 789 ? P42702 45 ? 833 ? 45 833 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
2 8V29 GLU B 598 ? UNP P40189 ? ? 'expression tag' 620 1  
2 8V29 GLN B 599 ? UNP P40189 ? ? 'expression tag' 621 2  
2 8V29 LYS B 600 ? UNP P40189 ? ? 'expression tag' 622 3  
2 8V29 LEU B 601 ? UNP P40189 ? ? 'expression tag' 623 4  
2 8V29 ILE B 602 ? UNP P40189 ? ? 'expression tag' 624 5  
2 8V29 SER B 603 ? UNP P40189 ? ? 'expression tag' 625 6  
2 8V29 GLU B 604 ? UNP P40189 ? ? 'expression tag' 626 7  
2 8V29 GLU B 605 ? UNP P40189 ? ? 'expression tag' 627 8  
2 8V29 ASP B 606 ? UNP P40189 ? ? 'expression tag' 628 9  
2 8V29 LEU B 607 ? UNP P40189 ? ? 'expression tag' 629 10 
2 8V29 GLY B 608 ? UNP P40189 ? ? 'expression tag' 630 11 
2 8V29 GLY B 609 ? UNP P40189 ? ? 'expression tag' 631 12 
2 8V29 GLU B 610 ? UNP P40189 ? ? 'expression tag' 632 13 
2 8V29 GLN B 611 ? UNP P40189 ? ? 'expression tag' 633 14 
2 8V29 LYS B 612 ? UNP P40189 ? ? 'expression tag' 634 15 
2 8V29 LEU B 613 ? UNP P40189 ? ? 'expression tag' 635 16 
2 8V29 ILE B 614 ? UNP P40189 ? ? 'expression tag' 636 17 
2 8V29 SER B 615 ? UNP P40189 ? ? 'expression tag' 637 18 
2 8V29 GLU B 616 ? UNP P40189 ? ? 'expression tag' 638 19 
2 8V29 GLU B 617 ? UNP P40189 ? ? 'expression tag' 639 20 
2 8V29 ASP B 618 ? UNP P40189 ? ? 'expression tag' 640 21 
2 8V29 LEU B 619 ? UNP P40189 ? ? 'expression tag' 641 22 
2 8V29 HIS B 620 ? UNP P40189 ? ? 'expression tag' 642 23 
2 8V29 HIS B 621 ? UNP P40189 ? ? 'expression tag' 643 24 
2 8V29 HIS B 622 ? UNP P40189 ? ? 'expression tag' 644 25 
2 8V29 HIS B 623 ? UNP P40189 ? ? 'expression tag' 645 26 
2 8V29 HIS B 624 ? UNP P40189 ? ? 'expression tag' 646 27 
2 8V29 HIS B 625 ? UNP P40189 ? ? 'expression tag' 647 28 
3 8V29 GLU C 790 ? UNP P42702 ? ? 'expression tag' 834 29 
3 8V29 GLN C 791 ? UNP P42702 ? ? 'expression tag' 835 30 
3 8V29 LYS C 792 ? UNP P42702 ? ? 'expression tag' 836 31 
3 8V29 LEU C 793 ? UNP P42702 ? ? 'expression tag' 837 32 
3 8V29 ILE C 794 ? UNP P42702 ? ? 'expression tag' 838 33 
3 8V29 SER C 795 ? UNP P42702 ? ? 'expression tag' 839 34 
3 8V29 GLU C 796 ? UNP P42702 ? ? 'expression tag' 840 35 
3 8V29 GLU C 797 ? UNP P42702 ? ? 'expression tag' 841 36 
3 8V29 ASP C 798 ? UNP P42702 ? ? 'expression tag' 842 37 
3 8V29 LEU C 799 ? UNP P42702 ? ? 'expression tag' 843 38 
3 8V29 GLY C 800 ? UNP P42702 ? ? 'expression tag' 844 39 
3 8V29 GLY C 801 ? UNP P42702 ? ? 'expression tag' 845 40 
3 8V29 GLU C 802 ? UNP P42702 ? ? 'expression tag' 846 41 
3 8V29 GLN C 803 ? UNP P42702 ? ? 'expression tag' 847 42 
3 8V29 LYS C 804 ? UNP P42702 ? ? 'expression tag' 848 43 
3 8V29 LEU C 805 ? UNP P42702 ? ? 'expression tag' 849 44 
3 8V29 ILE C 806 ? UNP P42702 ? ? 'expression tag' 850 45 
3 8V29 SER C 807 ? UNP P42702 ? ? 'expression tag' 851 46 
3 8V29 GLU C 808 ? UNP P42702 ? ? 'expression tag' 852 47 
3 8V29 GLU C 809 ? UNP P42702 ? ? 'expression tag' 853 48 
3 8V29 ASP C 810 ? UNP P42702 ? ? 'expression tag' 854 49 
3 8V29 LEU C 811 ? UNP P42702 ? ? 'expression tag' 855 50 
3 8V29 HIS C 812 ? UNP P42702 ? ? 'expression tag' 856 51 
3 8V29 HIS C 813 ? UNP P42702 ? ? 'expression tag' 857 52 
3 8V29 HIS C 814 ? UNP P42702 ? ? 'expression tag' 858 53 
3 8V29 HIS C 815 ? UNP P42702 ? ? 'expression tag' 859 54 
3 8V29 HIS C 816 ? UNP P42702 ? ? 'expression tag' 860 55 
3 8V29 HIS C 817 ? UNP P42702 ? ? 'expression tag' 861 56 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   trimeric 
_pdbx_struct_assembly.oligomeric_count     3 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 GLU A 9   ? GLN A 25  ? GLU A 34  GLN A 50  1 ? 17 
HELX_P HELX_P2  AA2 ASP A 26  ? GLN A 38  ? ASP A 51  GLN A 63  1 ? 13 
HELX_P HELX_P3  AA3 VAL A 42  ? GLU A 47  ? VAL A 67  GLU A 72  1 ? 6  
HELX_P HELX_P4  AA4 SER A 58  ? LEU A 65  ? SER A 83  LEU A 90  1 ? 8  
HELX_P HELX_P5  AA5 ARG A 67  ? LEU A 92  ? ARG A 92  LEU A 117 1 ? 26 
HELX_P HELX_P6  AA6 LYS A 94  ? GLY A 102 ? LYS A 119 GLY A 127 1 ? 9  
HELX_P HELX_P7  AA7 ILE A 105 ? ASP A 133 ? ILE A 130 ASP A 158 1 ? 29 
HELX_P HELX_P8  AA8 ASP A 158 ? TRP A 187 ? ASP A 183 TRP A 212 1 ? 30 
HELX_P HELX_P9  AA9 LYS B 29  ? HIS B 37  ? LYS B 51  HIS B 59  1 ? 9  
HELX_P HELX_P10 AB1 ASN B 39  ? ILE B 43  ? ASN B 61  ILE B 65  5 ? 5  
HELX_P HELX_P11 AB2 PRO B 53  ? GLU B 55  ? PRO B 75  GLU B 77  5 ? 3  
HELX_P HELX_P12 AB3 ASP B 193 ? TYR B 196 ? ASP B 215 TYR B 218 5 ? 4  
HELX_P HELX_P13 AB4 PRO B 225 ? SER B 229 ? PRO B 247 SER B 251 5 ? 5  
HELX_P HELX_P14 AB5 PRO B 251 ? THR B 255 ? PRO B 273 THR B 277 5 ? 5  
HELX_P HELX_P15 AB6 PRO B 333 ? ASN B 338 ? PRO B 355 ASN B 360 1 ? 6  
HELX_P HELX_P16 AB7 PRO B 521 ? ASN B 526 ? PRO B 543 ASN B 548 1 ? 6  
HELX_P HELX_P17 AB8 ARG C 116 ? PHE C 120 ? ARG C 160 PHE C 164 5 ? 5  
HELX_P HELX_P18 AB9 PRO C 166 ? ALA C 170 ? PRO C 210 ALA C 214 5 ? 5  
HELX_P HELX_P19 AC1 VAL C 318 ? ALA C 322 ? VAL C 362 ALA C 366 5 ? 5  
HELX_P HELX_P20 AC2 PRO C 344 ? SER C 348 ? PRO C 388 SER C 392 5 ? 5  
HELX_P HELX_P21 AC3 PRO C 516 ? ASN C 521 ? PRO C 560 ASN C 565 1 ? 6  
HELX_P HELX_P22 AC4 PRO C 704 ? ARG C 709 ? PRO C 748 ARG C 753 1 ? 6  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1  disulf ?    ? A CYS 6   SG  ? ? ? 1_555 A CYS 127 SG ? ? A CYS 31  A CYS 152 1_555 ? ? ? ? ? ? ? 2.033 ? ?               
disulf2  disulf ?    ? A CYS 49  SG  ? ? ? 1_555 A CYS 167 SG ? ? A CYS 74  A CYS 192 1_555 ? ? ? ? ? ? ? 2.035 ? ?               
disulf3  disulf ?    ? B CYS 6   SG  ? ? ? 1_555 B CYS 32  SG ? ? B CYS 28  B CYS 54  1_555 ? ? ? ? ? ? ? 2.030 ? ?               
disulf4  disulf ?    ? B CYS 26  SG  ? ? ? 1_555 B CYS 81  SG ? ? B CYS 48  B CYS 103 1_555 ? ? ? ? ? ? ? 2.033 ? ?               
disulf5  disulf ?    ? B CYS 112 SG  ? ? ? 1_555 B CYS 122 SG ? ? B CYS 134 B CYS 144 1_555 ? ? ? ? ? ? ? 2.031 ? ?               
disulf6  disulf ?    ? B CYS 150 SG  ? ? ? 1_555 B CYS 160 SG ? ? B CYS 172 B CYS 182 1_555 ? ? ? ? ? ? ? 2.030 ? ?               
disulf7  disulf ?    ? B CYS 436 SG  ? ? ? 1_555 B CYS 444 SG ? ? B CYS 458 B CYS 466 1_555 ? ? ? ? ? ? ? 2.032 ? ?               
disulf8  disulf ?    ? C CYS 11  SG  ? ? ? 1_555 C CYS 21  SG ? ? C CYS 55  C CYS 65  1_555 ? ? ? ? ? ? ? 2.032 ? ?               
disulf9  disulf ?    ? C CYS 38  SG  ? ? ? 1_555 C CYS 46  SG ? ? C CYS 82  C CYS 90  1_555 ? ? ? ? ? ? ? 2.033 ? ?               
disulf10 disulf ?    ? C CYS 169 SG  ? ? ? 1_555 C CYS 226 SG ? ? C CYS 213 C CYS 270 1_555 ? ? ? ? ? ? ? 2.029 ? ?               
disulf11 disulf ?    ? C CYS 297 SG  ? ? ? 1_555 C CYS 307 SG ? ? C CYS 341 C CYS 351 1_555 ? ? ? ? ? ? ? 2.030 ? ?               
disulf12 disulf ?    ? C CYS 422 SG  ? ? ? 1_555 C CYS 467 SG ? ? C CYS 466 C CYS 511 1_555 ? ? ? ? ? ? ? 2.031 ? ?               
disulf13 disulf ?    ? C CYS 611 SG  ? ? ? 1_555 C CYS 660 SG ? ? C CYS 655 C CYS 704 1_555 ? ? ? ? ? ? ? 2.030 ? ?               
disulf14 disulf ?    ? C CYS 618 SG  ? ? ? 1_555 C CYS 626 SG ? ? C CYS 662 C CYS 670 1_555 ? ? ? ? ? ? ? 2.031 ? ?               
covale1  covale one  ? A ASN 75  ND2 ? ? ? 1_555 D NAG .   C1 ? ? A ASN 100 D NAG 1   1_555 ? ? ? ? ? ? ? 1.439 ? N-Glycosylation 
covale2  covale one  ? B ASN 21  ND2 ? ? ? 1_555 E NAG .   C1 ? ? B ASN 43  E NAG 1   1_555 ? ? ? ? ? ? ? 1.445 ? N-Glycosylation 
covale3  covale one  ? B ASN 61  ND2 ? ? ? 1_555 N NAG .   C1 ? ? B ASN 83  B NAG 706 1_555 ? ? ? ? ? ? ? 1.442 ? N-Glycosylation 
covale4  covale one  ? B ASN 109 ND2 ? ? ? 1_555 I NAG .   C1 ? ? B ASN 131 B NAG 701 1_555 ? ? ? ? ? ? ? 1.440 ? N-Glycosylation 
covale5  covale one  ? B ASN 205 ND2 ? ? ? 1_555 K NAG .   C1 ? ? B ASN 227 B NAG 703 1_555 ? ? ? ? ? ? ? 1.443 ? N-Glycosylation 
covale6  covale one  ? B ASN 357 ND2 ? ? ? 1_555 M NAG .   C1 ? ? B ASN 379 B NAG 705 1_555 ? ? ? ? ? ? ? 1.442 ? N-Glycosylation 
covale7  covale one  ? B ASN 361 ND2 ? ? ? 1_555 L NAG .   C1 ? ? B ASN 383 B NAG 704 1_555 ? ? ? ? ? ? ? 1.443 ? N-Glycosylation 
covale8  covale one  ? B ASN 368 ND2 ? ? ? 1_555 J NAG .   C1 ? ? B ASN 390 B NAG 702 1_555 ? ? ? ? ? ? ? 1.443 ? N-Glycosylation 
covale9  covale one  ? C ASN 199 ND2 ? ? ? 1_555 H NAG .   C1 ? ? C ASN 243 H NAG 1   1_555 ? ? ? ? ? ? ? 1.441 ? N-Glycosylation 
covale10 covale one  ? C ASN 259 ND2 ? ? ? 1_555 O NAG .   C1 ? ? C ASN 303 C NAG 901 1_555 ? ? ? ? ? ? ? 1.452 ? N-Glycosylation 
covale11 covale one  ? C ASN 363 ND2 ? ? ? 1_555 F NAG .   C1 ? ? C ASN 407 F NAG 1   1_555 ? ? ? ? ? ? ? 1.439 ? N-Glycosylation 
covale12 covale one  ? C ASN 382 ND2 ? ? ? 1_555 G NAG .   C1 ? ? C ASN 426 G NAG 1   1_555 ? ? ? ? ? ? ? 1.440 ? N-Glycosylation 
covale13 covale one  ? C ASN 401 ND2 ? ? ? 1_555 Q NAG .   C1 ? ? C ASN 445 C NAG 903 1_555 ? ? ? ? ? ? ? 1.441 ? N-Glycosylation 
covale14 covale one  ? C ASN 445 ND2 ? ? ? 1_555 P NAG .   C1 ? ? C ASN 489 C NAG 902 1_555 ? ? ? ? ? ? ? 1.442 ? N-Glycosylation 
covale15 covale both ? D NAG .   O4  ? ? ? 1_555 D NAG .   C1 ? ? D NAG 1   D NAG 2   1_555 ? ? ? ? ? ? ? 1.444 ? ?               
covale16 covale both ? E NAG .   O4  ? ? ? 1_555 E NAG .   C1 ? ? E NAG 1   E NAG 2   1_555 ? ? ? ? ? ? ? 1.441 ? ?               
covale17 covale both ? F NAG .   O4  ? ? ? 1_555 F NAG .   C1 ? ? F NAG 1   F NAG 2   1_555 ? ? ? ? ? ? ? 1.442 ? ?               
covale18 covale both ? G NAG .   O4  ? ? ? 1_555 G NAG .   C1 ? ? G NAG 1   G NAG 2   1_555 ? ? ? ? ? ? ? 1.441 ? ?               
covale19 covale both ? H NAG .   O4  ? ? ? 1_555 H NAG .   C1 ? ? H NAG 1   H NAG 2   1_555 ? ? ? ? ? ? ? 1.443 ? ?               
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
disulf ? ? 
covale ? ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1  NAG D .   ? ASN A 75  ? NAG D 1   ? 1_555 ASN A 100 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
2  NAG E .   ? ASN B 21  ? NAG E 1   ? 1_555 ASN B 43  ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
3  NAG F .   ? ASN C 363 ? NAG F 1   ? 1_555 ASN C 407 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
4  NAG G .   ? ASN C 382 ? NAG G 1   ? 1_555 ASN C 426 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
5  NAG H .   ? ASN C 199 ? NAG H 1   ? 1_555 ASN C 243 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
6  NAG I .   ? ASN B 109 ? NAG B 701 ? 1_555 ASN B 131 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
7  NAG J .   ? ASN B 368 ? NAG B 702 ? 1_555 ASN B 390 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
8  NAG K .   ? ASN B 205 ? NAG B 703 ? 1_555 ASN B 227 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
9  NAG L .   ? ASN B 361 ? NAG B 704 ? 1_555 ASN B 383 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
10 NAG M .   ? ASN B 357 ? NAG B 705 ? 1_555 ASN B 379 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
11 NAG N .   ? ASN B 61  ? NAG B 706 ? 1_555 ASN B 83  ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
12 NAG O .   ? ASN C 259 ? NAG C 901 ? 1_555 ASN C 303 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
13 NAG P .   ? ASN C 445 ? NAG C 902 ? 1_555 ASN C 489 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
14 NAG Q .   ? ASN C 401 ? NAG C 903 ? 1_555 ASN C 445 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
15 CYS A 6   ? CYS A 127 ? CYS A 31  ? 1_555 CYS A 152 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
16 CYS A 49  ? CYS A 167 ? CYS A 74  ? 1_555 CYS A 192 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
17 CYS B 6   ? CYS B 32  ? CYS B 28  ? 1_555 CYS B 54  ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
18 CYS B 26  ? CYS B 81  ? CYS B 48  ? 1_555 CYS B 103 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
19 CYS B 112 ? CYS B 122 ? CYS B 134 ? 1_555 CYS B 144 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
20 CYS B 150 ? CYS B 160 ? CYS B 172 ? 1_555 CYS B 182 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
21 CYS B 436 ? CYS B 444 ? CYS B 458 ? 1_555 CYS B 466 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
22 CYS C 11  ? CYS C 21  ? CYS C 55  ? 1_555 CYS C 65  ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
23 CYS C 38  ? CYS C 46  ? CYS C 82  ? 1_555 CYS C 90  ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
24 CYS C 169 ? CYS C 226 ? CYS C 213 ? 1_555 CYS C 270 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
25 CYS C 297 ? CYS C 307 ? CYS C 341 ? 1_555 CYS C 351 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
26 CYS C 422 ? CYS C 467 ? CYS C 466 ? 1_555 CYS C 511 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
27 CYS C 611 ? CYS C 660 ? CYS C 655 ? 1_555 CYS C 704 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
28 CYS C 618 ? CYS C 626 ? CYS C 662 ? 1_555 CYS C 670 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 SER 10  B . ? SER 32  B PRO 11  B ? PRO 33  B 1 -1.39 
2 PHE 211 C . ? PHE 255 C PRO 212 C ? PRO 256 C 1 -1.54 
3 ASP 545 C . ? ASP 589 C PRO 546 C ? PRO 590 C 1 -0.78 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 4 ? 
AA2 ? 3 ? 
AA3 ? 4 ? 
AA4 ? 4 ? 
AA5 ? 4 ? 
AA6 ? 3 ? 
AA7 ? 4 ? 
AA8 ? 3 ? 
AA9 ? 4 ? 
AB1 ? 3 ? 
AB2 ? 4 ? 
AB3 ? 3 ? 
AB4 ? 4 ? 
AB5 ? 4 ? 
AB6 ? 5 ? 
AB7 ? 3 ? 
AB8 ? 3 ? 
AB9 ? 3 ? 
AC1 ? 4 ? 
AC2 ? 4 ? 
AC3 ? 5 ? 
AC4 ? 3 ? 
AC5 ? 4 ? 
AC6 ? 3 ? 
AC7 ? 4 ? 
AC8 ? 3 ? 
AC9 ? 4 ? 
AD1 ? 7 ? 
AD2 ? 3 ? 
AD3 ? 4 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? parallel      
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB1 2 3 ? anti-parallel 
AB2 1 2 ? anti-parallel 
AB2 2 3 ? anti-parallel 
AB2 3 4 ? anti-parallel 
AB3 1 2 ? anti-parallel 
AB3 2 3 ? anti-parallel 
AB4 1 2 ? anti-parallel 
AB4 2 3 ? anti-parallel 
AB4 3 4 ? anti-parallel 
AB5 1 2 ? anti-parallel 
AB5 2 3 ? anti-parallel 
AB5 3 4 ? anti-parallel 
AB6 1 2 ? anti-parallel 
AB6 2 3 ? anti-parallel 
AB6 3 4 ? parallel      
AB6 4 5 ? parallel      
AB7 1 2 ? anti-parallel 
AB7 2 3 ? anti-parallel 
AB8 1 2 ? anti-parallel 
AB8 2 3 ? anti-parallel 
AB9 1 2 ? anti-parallel 
AB9 2 3 ? anti-parallel 
AC1 1 2 ? anti-parallel 
AC1 2 3 ? anti-parallel 
AC1 3 4 ? anti-parallel 
AC2 1 2 ? anti-parallel 
AC2 2 3 ? anti-parallel 
AC2 3 4 ? anti-parallel 
AC3 1 2 ? parallel      
AC3 2 3 ? anti-parallel 
AC3 3 4 ? anti-parallel 
AC3 4 5 ? anti-parallel 
AC4 1 2 ? anti-parallel 
AC4 2 3 ? anti-parallel 
AC5 1 2 ? anti-parallel 
AC5 2 3 ? anti-parallel 
AC5 3 4 ? anti-parallel 
AC6 1 2 ? anti-parallel 
AC6 2 3 ? anti-parallel 
AC7 1 2 ? anti-parallel 
AC7 2 3 ? anti-parallel 
AC7 3 4 ? anti-parallel 
AC8 1 2 ? anti-parallel 
AC8 2 3 ? anti-parallel 
AC9 1 2 ? anti-parallel 
AC9 2 3 ? anti-parallel 
AC9 3 4 ? anti-parallel 
AD1 1 2 ? anti-parallel 
AD1 2 3 ? anti-parallel 
AD1 3 4 ? anti-parallel 
AD1 4 5 ? parallel      
AD1 5 6 ? anti-parallel 
AD1 6 7 ? anti-parallel 
AD2 1 2 ? anti-parallel 
AD2 2 3 ? anti-parallel 
AD3 1 2 ? anti-parallel 
AD3 2 3 ? anti-parallel 
AD3 3 4 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 GLY B 7   ? SER B 10  ? GLY B 29  SER B 32  
AA1 2 PHE B 22  ? LEU B 28  ? PHE B 44  LEU B 50  
AA1 3 ALA B 64  ? PHE B 69  ? ALA B 86  PHE B 91  
AA1 4 TYR B 57  ? ASN B 61  ? TYR B 79  ASN B 83  
AA2 1 VAL B 44  ? LYS B 46  ? VAL B 66  LYS B 68  
AA2 2 LEU B 79  ? LEU B 84  ? LEU B 101 LEU B 106 
AA2 3 GLU B 90  ? ILE B 96  ? GLU B 112 ILE B 118 
AA3 1 SER B 159 ? THR B 161 ? SER B 181 THR B 183 
AA3 2 MET B 120 ? GLU B 123 ? MET B 142 GLU B 145 
AA3 3 SER B 111 ? ASN B 115 ? SER B 133 ASN B 137 
AA3 4 VAL B 198 ? LYS B 199 ? VAL B 220 LYS B 221 
AA4 1 LYS B 146 ? ASP B 149 ? LYS B 168 ASP B 171 
AA4 2 ASN B 135 ? GLU B 141 ? ASN B 157 GLU B 163 
AA4 3 ILE B 172 ? ASN B 180 ? ILE B 194 ASN B 202 
AA4 4 GLY B 183 ? THR B 186 ? GLY B 205 THR B 208 
AA5 1 LYS B 146 ? ASP B 149 ? LYS B 168 ASP B 171 
AA5 2 ASN B 135 ? GLU B 141 ? ASN B 157 GLU B 163 
AA5 3 ILE B 172 ? ASN B 180 ? ILE B 194 ASN B 202 
AA5 4 ILE B 190 ? PHE B 192 ? ILE B 212 PHE B 214 
AA6 1 HIS B 204 ? ILE B 209 ? HIS B 226 ILE B 231 
AA6 2 LEU B 218 ? THR B 223 ? LEU B 240 THR B 245 
AA6 3 SER B 261 ? VAL B 264 ? SER B 283 VAL B 286 
AA7 1 SER B 248 ? GLN B 249 ? SER B 270 GLN B 271 
AA7 2 LEU B 233 ? THR B 241 ? LEU B 255 THR B 263 
AA7 3 GLU B 272 ? LYS B 281 ? GLU B 294 LYS B 303 
AA7 4 ALA B 295 ? ILE B 298 ? ALA B 317 ILE B 320 
AA8 1 PHE B 310 ? ILE B 314 ? PHE B 332 ILE B 336 
AA8 2 ARG B 323 ? TRP B 329 ? ARG B 345 TRP B 351 
AA8 3 LYS B 364 ? LEU B 369 ? LYS B 386 LEU B 391 
AA9 1 LEU B 355 ? VAL B 360 ? LEU B 377 VAL B 382 
AA9 2 ASP B 343 ? ARG B 350 ? ASP B 365 ARG B 372 
AA9 3 TYR B 374 ? ARG B 381 ? TYR B 396 ARG B 403 
AA9 4 LEU B 392 ? ILE B 394 ? LEU B 414 ILE B 416 
AB1 1 MET B 406 ? PRO B 412 ? MET B 428 PRO B 434 
AB1 2 LEU B 417 ? THR B 422 ? LEU B 439 THR B 444 
AB1 3 ARG B 457 ? TYR B 459 ? ARG B 479 TYR B 481 
AB2 1 ASP B 447 ? ASP B 452 ? ASP B 469 ASP B 474 
AB2 2 LYS B 430 ? VAL B 437 ? LYS B 452 VAL B 459 
AB2 3 CYS B 469 ? VAL B 477 ? CYS B 491 VAL B 499 
AB2 4 GLU B 486 ? TYR B 491 ? GLU B 508 TYR B 513 
AB3 1 VAL B 503 ? VAL B 508 ? VAL B 525 VAL B 530 
AB3 2 ALA B 513 ? TRP B 517 ? ALA B 535 TRP B 539 
AB3 3 GLU B 554 ? LEU B 557 ? GLU B 576 LEU B 579 
AB4 1 THR B 544 ? ASP B 549 ? THR B 566 ASP B 571 
AB4 2 ASN B 531 ? THR B 538 ? ASN B 553 THR B 560 
AB4 3 LEU B 565 ? TYR B 573 ? LEU B 587 TYR B 595 
AB4 4 GLY B 578 ? ASP B 580 ? GLY B 600 ASP B 602 
AB5 1 THR B 544 ? ASP B 549 ? THR B 566 ASP B 571 
AB5 2 ASN B 531 ? THR B 538 ? ASN B 553 THR B 560 
AB5 3 LEU B 565 ? TYR B 573 ? LEU B 587 TYR B 595 
AB5 4 PHE B 584 ? THR B 587 ? PHE B 606 THR B 609 
AB6 1 SER C 53  ? PRO C 57  ? SER C 97  PRO C 101 
AB6 2 VAL C 18  ? TRP C 23  ? VAL C 62  TRP C 67  
AB6 3 LEU C 9   ? THR C 13  ? LEU C 53  THR C 57  
AB6 4 SER C 89  ? LEU C 90  ? SER C 133 LEU C 134 
AB6 5 LEU C 188 ? GLU C 189 ? LEU C 232 GLU C 233 
AB7 1 ASP C 34  ? TYR C 35  ? ASP C 78  TYR C 79  
AB7 2 TYR C 64  ? LEU C 71  ? TYR C 108 LEU C 115 
AB7 3 CYS C 38  ? GLU C 40  ? CYS C 82  GLU C 84  
AB8 1 ASP C 34  ? TYR C 35  ? ASP C 78  TYR C 79  
AB8 2 TYR C 64  ? LEU C 71  ? TYR C 108 LEU C 115 
AB8 3 SER C 77  ? LEU C 83  ? SER C 121 LEU C 127 
AB9 1 ILE C 97  ? ASP C 103 ? ILE C 141 ASP C 147 
AB9 2 THR C 108 ? ASN C 114 ? THR C 152 ASN C 158 
AB9 3 LEU C 156 ? ALA C 162 ? LEU C 200 ALA C 206 
AC1 1 LYS C 142 ? THR C 149 ? LYS C 186 THR C 193 
AC1 2 ASN C 125 ? ARG C 134 ? ASN C 169 ARG C 178 
AC1 3 HIS C 172 ? ASP C 181 ? HIS C 216 ASP C 225 
AC1 4 LYS C 198 ? ILE C 200 ? LYS C 242 ILE C 244 
AC2 1 VAL C 210 ? PHE C 211 ? VAL C 254 PHE C 255 
AC2 2 ILE C 223 ? CYS C 227 ? ILE C 267 CYS C 271 
AC2 3 VAL C 253 ? ILE C 257 ? VAL C 297 ILE C 301 
AC2 4 ILE C 246 ? HIS C 247 ? ILE C 290 HIS C 291 
AC3 1 VAL C 216 ? LEU C 218 ? VAL C 260 LEU C 262 
AC3 2 ILE C 278 ? GLY C 286 ? ILE C 322 GLY C 330 
AC3 3 THR C 268 ? THR C 274 ? THR C 312 THR C 318 
AC3 4 VAL C 233 ? ILE C 238 ? VAL C 277 ILE C 282 
AC3 5 THR C 241 ? CYS C 243 ? THR C 285 CYS C 287 
AC4 1 GLN C 293 ? THR C 299 ? GLN C 337 THR C 343 
AC4 2 GLU C 304 ? ASN C 310 ? GLU C 348 ASN C 354 
AC4 3 GLN C 350 ? GLN C 354 ? GLN C 394 GLN C 398 
AC5 1 TYR C 335 ? ARG C 337 ? TYR C 379 ARG C 381 
AC5 2 SER C 324 ? GLU C 329 ? SER C 368 GLU C 373 
AC5 3 ILE C 361 ? HIS C 369 ? ILE C 405 HIS C 413 
AC5 4 ARG C 374 ? ASN C 382 ? ARG C 418 ASN C 426 
AC6 1 THR C 393 ? ASN C 401 ? THR C 437 ASN C 445 
AC6 2 ALA C 404 ? ASN C 414 ? ALA C 448 ASN C 458 
AC6 3 GLU C 444 ? ASP C 453 ? GLU C 488 ASP C 497 
AC7 1 GLU C 434 ? LYS C 441 ? GLU C 478 LYS C 485 
AC7 2 ASN C 419 ? LYS C 428 ? ASN C 463 LYS C 472 
AC7 3 LEU C 460 ? THR C 469 ? LEU C 504 THR C 513 
AC7 4 LYS C 482 ? LEU C 485 ? LYS C 526 LEU C 529 
AC8 1 THR C 497 ? TRP C 501 ? THR C 541 TRP C 545 
AC8 2 ASN C 507 ? TRP C 512 ? ASN C 551 TRP C 556 
AC8 3 LYS C 549 ? ARG C 553 ? LYS C 593 ARG C 597 
AC9 1 LEU C 540 ? PRO C 544 ? LEU C 584 PRO C 588 
AC9 2 SER C 526 ? SER C 532 ? SER C 570 SER C 576 
AC9 3 ILE C 560 ? LYS C 566 ? ILE C 604 LYS C 610 
AC9 4 SER C 575 ? ALA C 578 ? SER C 619 ALA C 622 
AD1 1 ASP C 629 ? PRO C 634 ? ASP C 673 PRO C 678 
AD1 2 ASP C 612 ? ASN C 619 ? ASP C 656 ASN C 663 
AD1 3 TYR C 653 ? CYS C 660 ? TYR C 697 CYS C 704 
AD1 4 TYR C 665 ? TYR C 674 ? TYR C 709 TYR C 718 
AD1 5 ILE C 589 ? MET C 595 ? ILE C 633 MET C 639 
AD1 6 GLY C 598 ? THR C 602 ? GLY C 642 THR C 646 
AD1 7 GLU C 639 ? ILE C 642 ? GLU C 683 ILE C 686 
AD2 1 PHE C 686 ? THR C 691 ? PHE C 730 THR C 735 
AD2 2 ILE C 696 ? TRP C 700 ? ILE C 740 TRP C 744 
AD2 3 THR C 751 ? ILE C 754 ? THR C 795 ILE C 798 
AD3 1 ILE C 739 ? ILE C 744 ? ILE C 783 ILE C 788 
AD3 2 LEU C 712 ? GLY C 720 ? LEU C 756 GLY C 764 
AD3 3 SER C 762 ? THR C 771 ? SER C 806 THR C 815 
AD3 4 GLY C 774 ? VAL C 784 ? GLY C 818 VAL C 828 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N SER B 10  ? N SER B 32  O VAL B 25  ? O VAL B 47  
AA1 2 3 N ALA B 24  ? N ALA B 46  O VAL B 67  ? O VAL B 89  
AA1 3 4 O SER B 66  ? O SER B 88  N THR B 58  ? N THR B 80  
AA2 1 2 N VAL B 44  ? N VAL B 66  O ASN B 82  ? O ASN B 104 
AA2 2 3 N LEU B 79  ? N LEU B 101 O ILE B 96  ? O ILE B 118 
AA3 1 2 O CYS B 160 ? O CYS B 182 N CYS B 122 ? N CYS B 144 
AA3 2 3 O ARG B 121 ? O ARG B 143 N ILE B 113 ? N ILE B 135 
AA3 3 4 N VAL B 114 ? N VAL B 136 O LYS B 199 ? O LYS B 221 
AA4 1 2 O PHE B 147 ? O PHE B 169 N SER B 140 ? N SER B 162 
AA4 2 3 N THR B 137 ? N THR B 159 O GLU B 177 ? O GLU B 199 
AA4 3 4 N ALA B 178 ? N ALA B 200 O VAL B 185 ? O VAL B 207 
AA5 1 2 O PHE B 147 ? O PHE B 169 N SER B 140 ? N SER B 162 
AA5 2 3 N THR B 137 ? N THR B 159 O GLU B 177 ? O GLU B 199 
AA5 3 4 N VAL B 174 ? N VAL B 196 O ILE B 190 ? O ILE B 212 
AA6 1 2 N ILE B 209 ? N ILE B 231 O LYS B 219 ? O LYS B 241 
AA6 2 3 N LEU B 220 ? N LEU B 242 O PHE B 262 ? O PHE B 284 
AA7 1 2 O SER B 248 ? O SER B 270 N TYR B 239 ? N TYR B 261 
AA7 2 3 N GLN B 238 ? N GLN B 260 O ARG B 276 ? O ARG B 298 
AA7 3 4 N TYR B 273 ? N TYR B 295 O GLY B 297 ? O GLY B 319 
AA8 1 2 N TRP B 311 ? N TRP B 333 O VAL B 328 ? O VAL B 350 
AA8 2 3 N ARG B 323 ? N ARG B 345 O LEU B 369 ? O LEU B 391 
AA9 1 2 O GLN B 356 ? O GLN B 378 N LEU B 348 ? N LEU B 370 
AA9 2 3 N GLU B 345 ? N GLU B 367 O THR B 379 ? O THR B 401 
AA9 3 4 N TYR B 374 ? N TYR B 396 O ILE B 394 ? O ILE B 416 
AB1 1 2 N MET B 406 ? N MET B 428 O THR B 422 ? O THR B 444 
AB1 2 3 N VAL B 419 ? N VAL B 441 O THR B 458 ? O THR B 480 
AB2 1 2 O GLU B 451 ? O GLU B 473 N TYR B 431 ? N TYR B 453 
AB2 2 3 N GLU B 434 ? N GLU B 456 O THR B 473 ? O THR B 495 
AB2 3 4 N TYR B 470 ? N TYR B 492 O ALA B 490 ? O ALA B 512 
AB3 1 2 N LYS B 506 ? N LYS B 528 O VAL B 514 ? O VAL B 536 
AB3 2 3 N LEU B 515 ? N LEU B 537 O TYR B 555 ? O TYR B 577 
AB4 1 2 O VAL B 548 ? O VAL B 570 N TYR B 532 ? N TYR B 554 
AB4 2 3 N PHE B 535 ? N PHE B 557 O ARG B 569 ? O ARG B 591 
AB4 3 4 N ALA B 572 ? N ALA B 594 O LYS B 579 ? O LYS B 601 
AB5 1 2 O VAL B 548 ? O VAL B 570 N TYR B 532 ? N TYR B 554 
AB5 2 3 N PHE B 535 ? N PHE B 557 O ARG B 569 ? O ARG B 591 
AB5 3 4 N VAL B 568 ? N VAL B 590 O PHE B 584 ? O PHE B 606 
AB6 1 2 O ILE C 56  ? O ILE C 100 N TRP C 19  ? N TRP C 63  
AB6 2 3 O ASN C 20  ? O ASN C 64  N VAL C 12  ? N VAL C 56  
AB6 3 4 N CYS C 11  ? N CYS C 55  O SER C 89  ? O SER C 133 
AB6 4 5 N LEU C 90  ? N LEU C 134 O LEU C 188 ? O LEU C 232 
AB7 1 2 N ASP C 34  ? N ASP C 78  O LEU C 71  ? O LEU C 115 
AB7 2 3 O GLU C 65  ? O GLU C 109 N GLU C 40  ? N GLU C 84  
AB8 1 2 N ASP C 34  ? N ASP C 78  O LEU C 71  ? O LEU C 115 
AB8 2 3 N ILE C 66  ? N ILE C 110 O PHE C 81  ? O PHE C 125 
AB9 1 2 N ASP C 103 ? N ASP C 147 O THR C 108 ? O THR C 152 
AB9 2 3 N LEU C 109 ? N LEU C 153 O TRP C 161 ? O TRP C 205 
AC1 1 2 O HIS C 146 ? O HIS C 190 N TRP C 128 ? N TRP C 172 
AC1 2 3 N LYS C 131 ? N LYS C 175 O GLU C 175 ? O GLU C 219 
AC1 3 4 N VAL C 174 ? N VAL C 218 O LYS C 198 ? O LYS C 242 
AC2 1 2 N PHE C 211 ? N PHE C 255 O CYS C 226 ? O CYS C 270 
AC2 2 3 N CYS C 227 ? N CYS C 271 O VAL C 253 ? O VAL C 297 
AC2 3 4 O ALA C 254 ? O ALA C 298 N ILE C 246 ? N ILE C 290 
AC3 1 2 N ILE C 217 ? N ILE C 261 O GLY C 286 ? O GLY C 330 
AC3 2 3 O PHE C 279 ? O PHE C 323 N PHE C 272 ? N PHE C 316 
AC3 3 4 O THR C 273 ? O THR C 317 N LEU C 234 ? N LEU C 278 
AC3 4 5 N ILE C 238 ? N ILE C 282 O THR C 241 ? O THR C 285 
AC4 1 2 N GLN C 293 ? N GLN C 337 O ASN C 310 ? O ASN C 354 
AC4 2 3 N ILE C 305 ? N ILE C 349 O PHE C 353 ? O PHE C 397 
AC5 1 2 O VAL C 336 ? O VAL C 380 N LEU C 327 ? N LEU C 371 
AC5 2 3 N THR C 326 ? N THR C 370 O ASN C 367 ? O ASN C 411 
AC5 3 4 N TYR C 362 ? N TYR C 406 O VAL C 381 ? O VAL C 425 
AC6 1 2 N LYS C 398 ? N LYS C 442 O LYS C 406 ? O LYS C 450 
AC6 2 3 N VAL C 405 ? N VAL C 449 O LEU C 452 ? O LEU C 496 
AC7 1 2 O ARG C 436 ? O ARG C 480 N ILE C 424 ? N ILE C 468 
AC7 2 3 N GLU C 423 ? N GLU C 467 O ARG C 466 ? O ARG C 510 
AC7 3 4 N PHE C 463 ? N PHE C 507 O LYS C 482 ? O LYS C 526 
AC8 1 2 N TRP C 498 ? N TRP C 542 O TYR C 511 ? O TYR C 555 
AC8 2 3 N ILE C 510 ? N ILE C 554 O ALA C 550 ? O ALA C 594 
AC9 1 2 O ILE C 543 ? O ILE C 587 N TYR C 527 ? N TYR C 571 
AC9 2 3 N ASN C 528 ? N ASN C 572 O VAL C 564 ? O VAL C 608 
AC9 3 4 N ILE C 561 ? N ILE C 605 O ILE C 577 ? O ILE C 621 
AD1 1 2 O VAL C 633 ? O VAL C 677 N TYR C 613 ? N TYR C 657 
AD1 2 3 N VAL C 614 ? N VAL C 658 O TYR C 658 ? O TYR C 702 
AD1 3 4 N PHE C 655 ? N PHE C 699 O MET C 671 ? O MET C 715 
AD1 4 5 O ILE C 672 ? O ILE C 716 N GLU C 590 ? N GLU C 634 
AD1 5 6 N MET C 595 ? N MET C 639 O GLY C 598 ? O GLY C 642 
AD1 6 7 N LEU C 601 ? N LEU C 645 O THR C 640 ? O THR C 684 
AD2 1 2 N THR C 687 ? N THR C 731 O LYS C 699 ? O LYS C 743 
AD2 2 3 N VAL C 698 ? N VAL C 742 O LEU C 752 ? O LEU C 796 
AD3 1 2 O ILE C 744 ? O ILE C 788 N TYR C 715 ? N TYR C 759 
AD3 2 3 N TYR C 718 ? N TYR C 762 O VAL C 766 ? O VAL C 810 
AD3 3 4 N THR C 771 ? N THR C 815 O GLY C 774 ? O GLY C 818 
# 
_pdbx_entry_details.entry_id                   8V29 
_pdbx_entry_details.has_ligand_of_interest     N 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 LEU A 65  ? ? -99.20  32.32   
2  1 VAL B 115 ? ? -121.79 -61.28  
3  1 PHE B 292 ? ? 33.87   56.56   
4  1 ASN B 404 ? ? -125.92 -169.89 
5  1 HIS B 425 ? ? 53.45   71.28   
6  1 LEU C 60  ? ? 59.16   14.37   
7  1 THR C 96  ? ? -93.16  52.40   
8  1 GLU C 180 ? ? -39.81  -29.35  
9  1 MET C 182 ? ? -172.04 135.95  
10 1 VAL C 185 ? ? -120.64 -62.23  
11 1 THR C 318 ? ? -127.31 -168.75 
12 1 PRO C 388 ? ? -66.21  -179.86 
13 1 ILE C 444 ? ? -121.23 -60.32  
14 1 PHE C 459 ? ? -99.96  32.03   
15 1 SER C 475 ? ? -163.21 -168.89 
16 1 CYS C 655 ? ? -98.95  -60.08  
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8V29 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    8V29 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.99 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               71514 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.5 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               'MULTIPLE SOURCES' 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'Human OSM in complex with gp130 and LIFR' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       '1, 2, 3' 
# 
_em_imaging.entry_id                        8V29 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             1400 
_em_imaging.nominal_defocus_max             2600 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              8V29 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                8V29 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A SER 160 ? A SER 135 
2   1 Y 1 A ASP 161 ? A ASP 136 
3   1 Y 1 A THR 162 ? A THR 137 
4   1 Y 1 A ALA 163 ? A ALA 138 
5   1 Y 1 A GLU 164 ? A GLU 139 
6   1 Y 1 A PRO 165 ? A PRO 140 
7   1 Y 1 A THR 166 ? A THR 141 
8   1 Y 1 A LYS 167 ? A LYS 142 
9   1 Y 1 A ALA 168 ? A ALA 143 
10  1 Y 1 A GLY 169 ? A GLY 144 
11  1 Y 1 A ARG 170 ? A ARG 145 
12  1 Y 1 A GLY 171 ? A GLY 146 
13  1 Y 1 A ALA 172 ? A ALA 147 
14  1 Y 1 A SER 173 ? A SER 148 
15  1 Y 1 A GLN 174 ? A GLN 149 
16  1 Y 1 A PRO 175 ? A PRO 150 
17  1 Y 1 A PRO 176 ? A PRO 151 
18  1 Y 1 A THR 177 ? A THR 152 
19  1 Y 1 A PRO 178 ? A PRO 153 
20  1 Y 1 A ASN 217 ? A ASN 192 
21  1 Y 1 A ARG 218 ? A ARG 193 
22  1 Y 1 A SER 219 ? A SER 194 
23  1 Y 1 A ARG 220 ? A ARG 195 
24  1 Y 1 A ARG 221 ? A ARG 196 
25  1 Y 1 B GLU 23  ? B GLU 1   
26  1 Y 1 B LEU 24  ? B LEU 2   
27  1 Y 1 B LEU 25  ? B LEU 3   
28  1 Y 1 B ASP 26  ? B ASP 4   
29  1 Y 1 B PHE 613 ? B PHE 591 
30  1 Y 1 B ALA 614 ? B ALA 592 
31  1 Y 1 B GLN 615 ? B GLN 593 
32  1 Y 1 B GLY 616 ? B GLY 594 
33  1 Y 1 B GLU 617 ? B GLU 595 
34  1 Y 1 B ILE 618 ? B ILE 596 
35  1 Y 1 B GLU 619 ? B GLU 597 
36  1 Y 1 B GLU 620 ? B GLU 598 
37  1 Y 1 B GLN 621 ? B GLN 599 
38  1 Y 1 B LYS 622 ? B LYS 600 
39  1 Y 1 B LEU 623 ? B LEU 601 
40  1 Y 1 B ILE 624 ? B ILE 602 
41  1 Y 1 B SER 625 ? B SER 603 
42  1 Y 1 B GLU 626 ? B GLU 604 
43  1 Y 1 B GLU 627 ? B GLU 605 
44  1 Y 1 B ASP 628 ? B ASP 606 
45  1 Y 1 B LEU 629 ? B LEU 607 
46  1 Y 1 B GLY 630 ? B GLY 608 
47  1 Y 1 B GLY 631 ? B GLY 609 
48  1 Y 1 B GLU 632 ? B GLU 610 
49  1 Y 1 B GLN 633 ? B GLN 611 
50  1 Y 1 B LYS 634 ? B LYS 612 
51  1 Y 1 B LEU 635 ? B LEU 613 
52  1 Y 1 B ILE 636 ? B ILE 614 
53  1 Y 1 B SER 637 ? B SER 615 
54  1 Y 1 B GLU 638 ? B GLU 616 
55  1 Y 1 B GLU 639 ? B GLU 617 
56  1 Y 1 B ASP 640 ? B ASP 618 
57  1 Y 1 B LEU 641 ? B LEU 619 
58  1 Y 1 B HIS 642 ? B HIS 620 
59  1 Y 1 B HIS 643 ? B HIS 621 
60  1 Y 1 B HIS 644 ? B HIS 622 
61  1 Y 1 B HIS 645 ? B HIS 623 
62  1 Y 1 B HIS 646 ? B HIS 624 
63  1 Y 1 B HIS 647 ? B HIS 625 
64  1 Y 1 C GLN 45  ? C GLN 1   
65  1 Y 1 C LYS 46  ? C LYS 2   
66  1 Y 1 C LYS 47  ? C LYS 3   
67  1 Y 1 C GLY 48  ? C GLY 4   
68  1 Y 1 C ALA 49  ? C ALA 5   
69  1 Y 1 C PRO 50  ? C PRO 6   
70  1 Y 1 C GLU 767 ? C GLU 723 
71  1 Y 1 C ARG 768 ? C ARG 724 
72  1 Y 1 C ASP 769 ? C ASP 725 
73  1 Y 1 C THR 770 ? C THR 726 
74  1 Y 1 C SER 771 ? C SER 727 
75  1 Y 1 C LYS 772 ? C LYS 728 
76  1 Y 1 C MET 773 ? C MET 729 
77  1 Y 1 C ARG 774 ? C ARG 730 
78  1 Y 1 C VAL 775 ? C VAL 731 
79  1 Y 1 C LEU 776 ? C LEU 732 
80  1 Y 1 C GLU 777 ? C GLU 733 
81  1 Y 1 C SER 778 ? C SER 734 
82  1 Y 1 C GLY 779 ? C GLY 735 
83  1 Y 1 C ARG 780 ? C ARG 736 
84  1 Y 1 C SER 781 ? C SER 737 
85  1 Y 1 C ASN 832 ? C ASN 788 
86  1 Y 1 C SER 833 ? C SER 789 
87  1 Y 1 C GLU 834 ? C GLU 790 
88  1 Y 1 C GLN 835 ? C GLN 791 
89  1 Y 1 C LYS 836 ? C LYS 792 
90  1 Y 1 C LEU 837 ? C LEU 793 
91  1 Y 1 C ILE 838 ? C ILE 794 
92  1 Y 1 C SER 839 ? C SER 795 
93  1 Y 1 C GLU 840 ? C GLU 796 
94  1 Y 1 C GLU 841 ? C GLU 797 
95  1 Y 1 C ASP 842 ? C ASP 798 
96  1 Y 1 C LEU 843 ? C LEU 799 
97  1 Y 1 C GLY 844 ? C GLY 800 
98  1 Y 1 C GLY 845 ? C GLY 801 
99  1 Y 1 C GLU 846 ? C GLU 802 
100 1 Y 1 C GLN 847 ? C GLN 803 
101 1 Y 1 C LYS 848 ? C LYS 804 
102 1 Y 1 C LEU 849 ? C LEU 805 
103 1 Y 1 C ILE 850 ? C ILE 806 
104 1 Y 1 C SER 851 ? C SER 807 
105 1 Y 1 C GLU 852 ? C GLU 808 
106 1 Y 1 C GLU 853 ? C GLU 809 
107 1 Y 1 C ASP 854 ? C ASP 810 
108 1 Y 1 C LEU 855 ? C LEU 811 
109 1 Y 1 C HIS 856 ? C HIS 812 
110 1 Y 1 C HIS 857 ? C HIS 813 
111 1 Y 1 C HIS 858 ? C HIS 814 
112 1 Y 1 C HIS 859 ? C HIS 815 
113 1 Y 1 C HIS 860 ? C HIS 816 
114 1 Y 1 C HIS 861 ? C HIS 817 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
NAG C1   C N R 247 
NAG C2   C N R 248 
NAG C3   C N R 249 
NAG C4   C N S 250 
NAG C5   C N R 251 
NAG C6   C N N 252 
NAG C7   C N N 253 
NAG C8   C N N 254 
NAG N2   N N N 255 
NAG O1   O N N 256 
NAG O3   O N N 257 
NAG O4   O N N 258 
NAG O5   O N N 259 
NAG O6   O N N 260 
NAG O7   O N N 261 
NAG H1   H N N 262 
NAG H2   H N N 263 
NAG H3   H N N 264 
NAG H4   H N N 265 
NAG H5   H N N 266 
NAG H61  H N N 267 
NAG H62  H N N 268 
NAG H81  H N N 269 
NAG H82  H N N 270 
NAG H83  H N N 271 
NAG HN2  H N N 272 
NAG HO1  H N N 273 
NAG HO3  H N N 274 
NAG HO4  H N N 275 
NAG HO6  H N N 276 
PHE N    N N N 277 
PHE CA   C N S 278 
PHE C    C N N 279 
PHE O    O N N 280 
PHE CB   C N N 281 
PHE CG   C Y N 282 
PHE CD1  C Y N 283 
PHE CD2  C Y N 284 
PHE CE1  C Y N 285 
PHE CE2  C Y N 286 
PHE CZ   C Y N 287 
PHE OXT  O N N 288 
PHE H    H N N 289 
PHE H2   H N N 290 
PHE HA   H N N 291 
PHE HB2  H N N 292 
PHE HB3  H N N 293 
PHE HD1  H N N 294 
PHE HD2  H N N 295 
PHE HE1  H N N 296 
PHE HE2  H N N 297 
PHE HZ   H N N 298 
PHE HXT  H N N 299 
PRO N    N N N 300 
PRO CA   C N S 301 
PRO C    C N N 302 
PRO O    O N N 303 
PRO CB   C N N 304 
PRO CG   C N N 305 
PRO CD   C N N 306 
PRO OXT  O N N 307 
PRO H    H N N 308 
PRO HA   H N N 309 
PRO HB2  H N N 310 
PRO HB3  H N N 311 
PRO HG2  H N N 312 
PRO HG3  H N N 313 
PRO HD2  H N N 314 
PRO HD3  H N N 315 
PRO HXT  H N N 316 
SER N    N N N 317 
SER CA   C N S 318 
SER C    C N N 319 
SER O    O N N 320 
SER CB   C N N 321 
SER OG   O N N 322 
SER OXT  O N N 323 
SER H    H N N 324 
SER H2   H N N 325 
SER HA   H N N 326 
SER HB2  H N N 327 
SER HB3  H N N 328 
SER HG   H N N 329 
SER HXT  H N N 330 
THR N    N N N 331 
THR CA   C N S 332 
THR C    C N N 333 
THR O    O N N 334 
THR CB   C N R 335 
THR OG1  O N N 336 
THR CG2  C N N 337 
THR OXT  O N N 338 
THR H    H N N 339 
THR H2   H N N 340 
THR HA   H N N 341 
THR HB   H N N 342 
THR HG1  H N N 343 
THR HG21 H N N 344 
THR HG22 H N N 345 
THR HG23 H N N 346 
THR HXT  H N N 347 
TRP N    N N N 348 
TRP CA   C N S 349 
TRP C    C N N 350 
TRP O    O N N 351 
TRP CB   C N N 352 
TRP CG   C Y N 353 
TRP CD1  C Y N 354 
TRP CD2  C Y N 355 
TRP NE1  N Y N 356 
TRP CE2  C Y N 357 
TRP CE3  C Y N 358 
TRP CZ2  C Y N 359 
TRP CZ3  C Y N 360 
TRP CH2  C Y N 361 
TRP OXT  O N N 362 
TRP H    H N N 363 
TRP H2   H N N 364 
TRP HA   H N N 365 
TRP HB2  H N N 366 
TRP HB3  H N N 367 
TRP HD1  H N N 368 
TRP HE1  H N N 369 
TRP HE3  H N N 370 
TRP HZ2  H N N 371 
TRP HZ3  H N N 372 
TRP HH2  H N N 373 
TRP HXT  H N N 374 
TYR N    N N N 375 
TYR CA   C N S 376 
TYR C    C N N 377 
TYR O    O N N 378 
TYR CB   C N N 379 
TYR CG   C Y N 380 
TYR CD1  C Y N 381 
TYR CD2  C Y N 382 
TYR CE1  C Y N 383 
TYR CE2  C Y N 384 
TYR CZ   C Y N 385 
TYR OH   O N N 386 
TYR OXT  O N N 387 
TYR H    H N N 388 
TYR H2   H N N 389 
TYR HA   H N N 390 
TYR HB2  H N N 391 
TYR HB3  H N N 392 
TYR HD1  H N N 393 
TYR HD2  H N N 394 
TYR HE1  H N N 395 
TYR HE2  H N N 396 
TYR HH   H N N 397 
TYR HXT  H N N 398 
VAL N    N N N 399 
VAL CA   C N S 400 
VAL C    C N N 401 
VAL O    O N N 402 
VAL CB   C N N 403 
VAL CG1  C N N 404 
VAL CG2  C N N 405 
VAL OXT  O N N 406 
VAL H    H N N 407 
VAL H2   H N N 408 
VAL HA   H N N 409 
VAL HB   H N N 410 
VAL HG11 H N N 411 
VAL HG12 H N N 412 
VAL HG13 H N N 413 
VAL HG21 H N N 414 
VAL HG22 H N N 415 
VAL HG23 H N N 416 
VAL HXT  H N N 417 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
NAG C1  C2   sing N N 235 
NAG C1  O1   sing N N 236 
NAG C1  O5   sing N N 237 
NAG C1  H1   sing N N 238 
NAG C2  C3   sing N N 239 
NAG C2  N2   sing N N 240 
NAG C2  H2   sing N N 241 
NAG C3  C4   sing N N 242 
NAG C3  O3   sing N N 243 
NAG C3  H3   sing N N 244 
NAG C4  C5   sing N N 245 
NAG C4  O4   sing N N 246 
NAG C4  H4   sing N N 247 
NAG C5  C6   sing N N 248 
NAG C5  O5   sing N N 249 
NAG C5  H5   sing N N 250 
NAG C6  O6   sing N N 251 
NAG C6  H61  sing N N 252 
NAG C6  H62  sing N N 253 
NAG C7  C8   sing N N 254 
NAG C7  N2   sing N N 255 
NAG C7  O7   doub N N 256 
NAG C8  H81  sing N N 257 
NAG C8  H82  sing N N 258 
NAG C8  H83  sing N N 259 
NAG N2  HN2  sing N N 260 
NAG O1  HO1  sing N N 261 
NAG O3  HO3  sing N N 262 
NAG O4  HO4  sing N N 263 
NAG O6  HO6  sing N N 264 
PHE N   CA   sing N N 265 
PHE N   H    sing N N 266 
PHE N   H2   sing N N 267 
PHE CA  C    sing N N 268 
PHE CA  CB   sing N N 269 
PHE CA  HA   sing N N 270 
PHE C   O    doub N N 271 
PHE C   OXT  sing N N 272 
PHE CB  CG   sing N N 273 
PHE CB  HB2  sing N N 274 
PHE CB  HB3  sing N N 275 
PHE CG  CD1  doub Y N 276 
PHE CG  CD2  sing Y N 277 
PHE CD1 CE1  sing Y N 278 
PHE CD1 HD1  sing N N 279 
PHE CD2 CE2  doub Y N 280 
PHE CD2 HD2  sing N N 281 
PHE CE1 CZ   doub Y N 282 
PHE CE1 HE1  sing N N 283 
PHE CE2 CZ   sing Y N 284 
PHE CE2 HE2  sing N N 285 
PHE CZ  HZ   sing N N 286 
PHE OXT HXT  sing N N 287 
PRO N   CA   sing N N 288 
PRO N   CD   sing N N 289 
PRO N   H    sing N N 290 
PRO CA  C    sing N N 291 
PRO CA  CB   sing N N 292 
PRO CA  HA   sing N N 293 
PRO C   O    doub N N 294 
PRO C   OXT  sing N N 295 
PRO CB  CG   sing N N 296 
PRO CB  HB2  sing N N 297 
PRO CB  HB3  sing N N 298 
PRO CG  CD   sing N N 299 
PRO CG  HG2  sing N N 300 
PRO CG  HG3  sing N N 301 
PRO CD  HD2  sing N N 302 
PRO CD  HD3  sing N N 303 
PRO OXT HXT  sing N N 304 
SER N   CA   sing N N 305 
SER N   H    sing N N 306 
SER N   H2   sing N N 307 
SER CA  C    sing N N 308 
SER CA  CB   sing N N 309 
SER CA  HA   sing N N 310 
SER C   O    doub N N 311 
SER C   OXT  sing N N 312 
SER CB  OG   sing N N 313 
SER CB  HB2  sing N N 314 
SER CB  HB3  sing N N 315 
SER OG  HG   sing N N 316 
SER OXT HXT  sing N N 317 
THR N   CA   sing N N 318 
THR N   H    sing N N 319 
THR N   H2   sing N N 320 
THR CA  C    sing N N 321 
THR CA  CB   sing N N 322 
THR CA  HA   sing N N 323 
THR C   O    doub N N 324 
THR C   OXT  sing N N 325 
THR CB  OG1  sing N N 326 
THR CB  CG2  sing N N 327 
THR CB  HB   sing N N 328 
THR OG1 HG1  sing N N 329 
THR CG2 HG21 sing N N 330 
THR CG2 HG22 sing N N 331 
THR CG2 HG23 sing N N 332 
THR OXT HXT  sing N N 333 
TRP N   CA   sing N N 334 
TRP N   H    sing N N 335 
TRP N   H2   sing N N 336 
TRP CA  C    sing N N 337 
TRP CA  CB   sing N N 338 
TRP CA  HA   sing N N 339 
TRP C   O    doub N N 340 
TRP C   OXT  sing N N 341 
TRP CB  CG   sing N N 342 
TRP CB  HB2  sing N N 343 
TRP CB  HB3  sing N N 344 
TRP CG  CD1  doub Y N 345 
TRP CG  CD2  sing Y N 346 
TRP CD1 NE1  sing Y N 347 
TRP CD1 HD1  sing N N 348 
TRP CD2 CE2  doub Y N 349 
TRP CD2 CE3  sing Y N 350 
TRP NE1 CE2  sing Y N 351 
TRP NE1 HE1  sing N N 352 
TRP CE2 CZ2  sing Y N 353 
TRP CE3 CZ3  doub Y N 354 
TRP CE3 HE3  sing N N 355 
TRP CZ2 CH2  doub Y N 356 
TRP CZ2 HZ2  sing N N 357 
TRP CZ3 CH2  sing Y N 358 
TRP CZ3 HZ3  sing N N 359 
TRP CH2 HH2  sing N N 360 
TRP OXT HXT  sing N N 361 
TYR N   CA   sing N N 362 
TYR N   H    sing N N 363 
TYR N   H2   sing N N 364 
TYR CA  C    sing N N 365 
TYR CA  CB   sing N N 366 
TYR CA  HA   sing N N 367 
TYR C   O    doub N N 368 
TYR C   OXT  sing N N 369 
TYR CB  CG   sing N N 370 
TYR CB  HB2  sing N N 371 
TYR CB  HB3  sing N N 372 
TYR CG  CD1  doub Y N 373 
TYR CG  CD2  sing Y N 374 
TYR CD1 CE1  sing Y N 375 
TYR CD1 HD1  sing N N 376 
TYR CD2 CE2  doub Y N 377 
TYR CD2 HD2  sing N N 378 
TYR CE1 CZ   doub Y N 379 
TYR CE1 HE1  sing N N 380 
TYR CE2 CZ   sing Y N 381 
TYR CE2 HE2  sing N N 382 
TYR CZ  OH   sing N N 383 
TYR OH  HH   sing N N 384 
TYR OXT HXT  sing N N 385 
VAL N   CA   sing N N 386 
VAL N   H    sing N N 387 
VAL N   H2   sing N N 388 
VAL CA  C    sing N N 389 
VAL CA  CB   sing N N 390 
VAL CA  HA   sing N N 391 
VAL C   O    doub N N 392 
VAL C   OXT  sing N N 393 
VAL CB  CG1  sing N N 394 
VAL CB  CG2  sing N N 395 
VAL CB  HB   sing N N 396 
VAL CG1 HG11 sing N N 397 
VAL CG1 HG12 sing N N 398 
VAL CG1 HG13 sing N N 399 
VAL CG2 HG21 sing N N 400 
VAL CG2 HG22 sing N N 401 
VAL CG2 HG23 sing N N 402 
VAL OXT HXT  sing N N 403 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2023-11-22 
_em_admin.deposition_site    RCSB 
_em_admin.entry_id           8V29 
_em_admin.last_update        2024-11-20 
_em_admin.map_release_date   2024-11-20 
_em_admin.title              'Cryo-EM structure of human type I OSM receptor complex: model for full extracellular assembly' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         40 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 BIOQUANTUM (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? ? ? 
'IMAGE ACQUISITION'        ? 2  ? ? 1 ? ? 
MASKING                    ? 3  ? ? ? ? ? 
'CTF CORRECTION'           ? 4  1 ? ? ? ? 
'LAYERLINE INDEXING'       ? 5  ? ? ? ? ? 
'DIFFRACTION INDEXING'     ? 6  ? ? ? ? ? 
'MODEL FITTING'            ? 7  ? ? ? ? ? 
'MODEL REFINEMENT'         ? 8  ? ? ? ? ? 
OTHER                      ? 9  ? ? ? ? ? 
'INITIAL EULER ASSIGNMENT' ? 10 1 ? ? ? ? 
'FINAL EULER ASSIGNMENT'   ? 11 1 ? ? ? ? 
CLASSIFICATION             ? 12 1 ? ? ? ? 
RECONSTRUCTION             ? 13 1 ? ? ? ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'Other private' 
_pdbx_audit_support.country                ? 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
loop_
_pdbx_entity_branch_list.entity_id 
_pdbx_entity_branch_list.comp_id 
_pdbx_entity_branch_list.num 
_pdbx_entity_branch_list.hetero 
4 NAG 1 n 
4 NAG 2 n 
# 
_atom_sites.entry_id                    8V29 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1     N N   . ALA A 1 1   ? 141.115 180.513 157.357 1.00 63.79  ? 26  ALA A N   1 
ATOM   2     C CA  . ALA A 1 1   ? 142.520 180.129 157.292 1.00 63.79  ? 26  ALA A CA  1 
ATOM   3     C C   . ALA A 1 1   ? 142.715 178.692 157.763 1.00 63.79  ? 26  ALA A C   1 
ATOM   4     O O   . ALA A 1 1   ? 142.973 177.795 156.961 1.00 63.79  ? 26  ALA A O   1 
ATOM   5     C CB  . ALA A 1 1   ? 143.369 181.080 158.121 1.00 63.79  ? 26  ALA A CB  1 
ATOM   6     N N   . ALA A 1 2   ? 142.590 178.480 159.071 1.00 65.80  ? 27  ALA A N   1 
ATOM   7     C CA  . ALA A 1 2   ? 142.746 177.150 159.641 1.00 65.80  ? 27  ALA A CA  1 
ATOM   8     C C   . ALA A 1 2   ? 141.444 176.367 159.532 1.00 65.80  ? 27  ALA A C   1 
ATOM   9     O O   . ALA A 1 2   ? 140.360 176.894 159.795 1.00 65.80  ? 27  ALA A O   1 
ATOM   10    C CB  . ALA A 1 2   ? 143.181 177.242 161.103 1.00 65.80  ? 27  ALA A CB  1 
ATOM   11    N N   . ILE A 1 3   ? 141.561 175.099 159.144 1.00 66.19  ? 28  ILE A N   1 
ATOM   12    C CA  . ILE A 1 3   ? 140.388 174.249 158.993 1.00 66.19  ? 28  ILE A CA  1 
ATOM   13    C C   . ILE A 1 3   ? 139.857 173.848 160.366 1.00 66.19  ? 28  ILE A C   1 
ATOM   14    O O   . ILE A 1 3   ? 140.550 173.927 161.383 1.00 66.19  ? 28  ILE A O   1 
ATOM   15    C CB  . ILE A 1 3   ? 140.710 173.013 158.135 1.00 66.19  ? 28  ILE A CB  1 
ATOM   16    C CG1 . ILE A 1 3   ? 142.035 172.388 158.580 1.00 66.19  ? 28  ILE A CG1 1 
ATOM   17    C CG2 . ILE A 1 3   ? 140.757 173.385 156.661 1.00 66.19  ? 28  ILE A CG2 1 
ATOM   18    C CD1 . ILE A 1 3   ? 142.469 171.209 157.739 1.00 66.19  ? 28  ILE A CD1 1 
ATOM   19    N N   . GLY A 1 4   ? 138.598 173.415 160.388 1.00 68.80  ? 29  GLY A N   1 
ATOM   20    C CA  . GLY A 1 4   ? 137.977 172.963 161.617 1.00 68.80  ? 29  GLY A CA  1 
ATOM   21    C C   . GLY A 1 4   ? 138.577 171.669 162.123 1.00 68.80  ? 29  GLY A C   1 
ATOM   22    O O   . GLY A 1 4   ? 139.076 171.603 163.250 1.00 68.80  ? 29  GLY A O   1 
ATOM   23    N N   . SER A 1 5   ? 138.531 170.630 161.294 1.00 77.51  ? 30  SER A N   1 
ATOM   24    C CA  . SER A 1 5   ? 139.136 169.342 161.601 1.00 77.51  ? 30  SER A CA  1 
ATOM   25    C C   . SER A 1 5   ? 140.405 169.181 160.775 1.00 77.51  ? 30  SER A C   1 
ATOM   26    O O   . SER A 1 5   ? 140.396 169.422 159.563 1.00 77.51  ? 30  SER A O   1 
ATOM   27    C CB  . SER A 1 5   ? 138.165 168.195 161.315 1.00 77.51  ? 30  SER A CB  1 
ATOM   28    O OG  . SER A 1 5   ? 138.548 167.019 162.007 1.00 77.51  ? 30  SER A OG  1 
ATOM   29    N N   . CYS A 1 6   ? 141.492 168.775 161.435 1.00 89.52  ? 31  CYS A N   1 
ATOM   30    C CA  . CYS A 1 6   ? 142.774 168.640 160.752 1.00 89.52  ? 31  CYS A CA  1 
ATOM   31    C C   . CYS A 1 6   ? 142.782 167.499 159.743 1.00 89.52  ? 31  CYS A C   1 
ATOM   32    O O   . CYS A 1 6   ? 143.669 167.456 158.884 1.00 89.52  ? 31  CYS A O   1 
ATOM   33    C CB  . CYS A 1 6   ? 143.893 168.443 161.777 1.00 89.52  ? 31  CYS A CB  1 
ATOM   34    S SG  . CYS A 1 6   ? 143.671 167.026 162.878 1.00 89.52  ? 31  CYS A SG  1 
ATOM   35    N N   . SER A 1 7   ? 141.823 166.580 159.824 1.00 73.20  ? 32  SER A N   1 
ATOM   36    C CA  . SER A 1 7   ? 141.735 165.477 158.879 1.00 73.20  ? 32  SER A CA  1 
ATOM   37    C C   . SER A 1 7   ? 140.280 165.054 158.748 1.00 73.20  ? 32  SER A C   1 
ATOM   38    O O   . SER A 1 7   ? 139.477 165.247 159.665 1.00 73.20  ? 32  SER A O   1 
ATOM   39    C CB  . SER A 1 7   ? 142.597 164.287 159.313 1.00 73.20  ? 32  SER A CB  1 
ATOM   40    O OG  . SER A 1 7   ? 142.843 163.413 158.225 1.00 73.20  ? 32  SER A OG  1 
ATOM   41    N N   . LYS A 1 8   ? 139.948 164.474 157.595 1.00 69.77  ? 33  LYS A N   1 
ATOM   42    C CA  . LYS A 1 8   ? 138.591 164.033 157.317 1.00 69.77  ? 33  LYS A CA  1 
ATOM   43    C C   . LYS A 1 8   ? 138.464 162.527 157.139 1.00 69.77  ? 33  LYS A C   1 
ATOM   44    O O   . LYS A 1 8   ? 137.341 162.032 156.997 1.00 69.77  ? 33  LYS A O   1 
ATOM   45    C CB  . LYS A 1 8   ? 138.051 164.738 156.063 1.00 69.77  ? 33  LYS A CB  1 
ATOM   46    C CG  . LYS A 1 8   ? 136.565 165.049 156.118 1.00 69.77  ? 33  LYS A CG  1 
ATOM   47    C CD  . LYS A 1 8   ? 136.237 165.965 157.285 1.00 69.77  ? 33  LYS A CD  1 
ATOM   48    C CE  . LYS A 1 8   ? 134.748 166.257 157.353 1.00 69.77  ? 33  LYS A CE  1 
ATOM   49    N NZ  . LYS A 1 8   ? 134.260 166.923 156.115 1.00 69.77  ? 33  LYS A NZ  1 
ATOM   50    N N   . GLU A 1 9   ? 139.571 161.788 157.145 1.00 54.78  ? 34  GLU A N   1 
ATOM   51    C CA  . GLU A 1 9   ? 139.550 160.340 156.964 1.00 54.78  ? 34  GLU A CA  1 
ATOM   52    C C   . GLU A 1 9   ? 139.604 159.675 158.336 1.00 54.78  ? 34  GLU A C   1 
ATOM   53    O O   . GLU A 1 9   ? 140.643 159.693 159.009 1.00 54.78  ? 34  GLU A O   1 
ATOM   54    C CB  . GLU A 1 9   ? 140.705 159.885 156.076 1.00 54.78  ? 34  GLU A CB  1 
ATOM   55    C CG  . GLU A 1 9   ? 140.667 160.458 154.669 1.00 54.78  ? 34  GLU A CG  1 
ATOM   56    C CD  . GLU A 1 9   ? 141.773 159.913 153.788 1.00 54.78  ? 34  GLU A CD  1 
ATOM   57    O OE1 . GLU A 1 9   ? 142.499 159.002 154.238 1.00 54.78  ? 34  GLU A OE1 1 
ATOM   58    O OE2 . GLU A 1 9   ? 141.916 160.397 152.646 1.00 54.78  ? 34  GLU A OE2 1 
ATOM   59    N N   . TYR A 1 10  ? 138.475 159.087 158.740 1.00 40.52  ? 35  TYR A N   1 
ATOM   60    C CA  . TYR A 1 10  ? 138.369 158.474 160.060 1.00 40.52  ? 35  TYR A CA  1 
ATOM   61    C C   . TYR A 1 10  ? 139.378 157.346 160.234 1.00 40.52  ? 35  TYR A C   1 
ATOM   62    O O   . TYR A 1 10  ? 139.929 157.159 161.325 1.00 40.52  ? 35  TYR A O   1 
ATOM   63    C CB  . TYR A 1 10  ? 136.941 157.969 160.274 1.00 40.52  ? 35  TYR A CB  1 
ATOM   64    C CG  . TYR A 1 10  ? 136.797 156.908 161.338 1.00 40.52  ? 35  TYR A CG  1 
ATOM   65    C CD1 . TYR A 1 10  ? 136.787 157.245 162.684 1.00 40.52  ? 35  TYR A CD1 1 
ATOM   66    C CD2 . TYR A 1 10  ? 136.657 155.570 160.996 1.00 40.52  ? 35  TYR A CD2 1 
ATOM   67    C CE1 . TYR A 1 10  ? 136.651 156.279 163.660 1.00 40.52  ? 35  TYR A CE1 1 
ATOM   68    C CE2 . TYR A 1 10  ? 136.521 154.597 161.965 1.00 40.52  ? 35  TYR A CE2 1 
ATOM   69    C CZ  . TYR A 1 10  ? 136.519 154.957 163.295 1.00 40.52  ? 35  TYR A CZ  1 
ATOM   70    O OH  . TYR A 1 10  ? 136.383 153.993 164.265 1.00 40.52  ? 35  TYR A OH  1 
ATOM   71    N N   . ARG A 1 11  ? 139.646 156.594 159.165 1.00 41.95  ? 36  ARG A N   1 
ATOM   72    C CA  . ARG A 1 11  ? 140.577 155.474 159.260 1.00 41.95  ? 36  ARG A CA  1 
ATOM   73    C C   . ARG A 1 11  ? 141.985 155.955 159.590 1.00 41.95  ? 36  ARG A C   1 
ATOM   74    O O   . ARG A 1 11  ? 142.619 155.459 160.532 1.00 41.95  ? 36  ARG A O   1 
ATOM   75    C CB  . ARG A 1 11  ? 140.572 154.675 157.956 1.00 41.95  ? 36  ARG A CB  1 
ATOM   76    C CG  . ARG A 1 11  ? 139.210 154.581 157.291 1.00 41.95  ? 36  ARG A CG  1 
ATOM   77    C CD  . ARG A 1 11  ? 138.230 153.795 158.146 1.00 41.95  ? 36  ARG A CD  1 
ATOM   78    N NE  . ARG A 1 11  ? 136.902 153.743 157.545 1.00 41.95  ? 36  ARG A NE  1 
ATOM   79    C CZ  . ARG A 1 11  ? 135.851 153.153 158.105 1.00 41.95  ? 36  ARG A CZ  1 
ATOM   80    N NH1 . ARG A 1 11  ? 134.679 153.154 157.486 1.00 41.95  ? 36  ARG A NH1 1 
ATOM   81    N NH2 . ARG A 1 11  ? 135.971 152.564 159.286 1.00 41.95  ? 36  ARG A NH2 1 
ATOM   82    N N   . VAL A 1 12  ? 142.493 156.926 158.827 1.00 30.30  ? 37  VAL A N   1 
ATOM   83    C CA  . VAL A 1 12  ? 143.849 157.397 159.083 1.00 30.30  ? 37  VAL A CA  1 
ATOM   84    C C   . VAL A 1 12  ? 143.907 158.160 160.399 1.00 30.30  ? 37  VAL A C   1 
ATOM   85    O O   . VAL A 1 12  ? 144.939 158.154 161.077 1.00 30.30  ? 37  VAL A O   1 
ATOM   86    C CB  . VAL A 1 12  ? 144.372 158.249 157.909 1.00 30.30  ? 37  VAL A CB  1 
ATOM   87    C CG1 . VAL A 1 12  ? 143.666 159.590 157.853 1.00 30.30  ? 37  VAL A CG1 1 
ATOM   88    C CG2 . VAL A 1 12  ? 145.880 158.433 158.013 1.00 30.30  ? 37  VAL A CG2 1 
ATOM   89    N N   . LEU A 1 13  ? 142.806 158.798 160.806 1.00 26.81  ? 38  LEU A N   1 
ATOM   90    C CA  . LEU A 1 13  ? 142.801 159.479 162.098 1.00 26.81  ? 38  LEU A CA  1 
ATOM   91    C C   . LEU A 1 13  ? 142.916 158.478 163.243 1.00 26.81  ? 38  LEU A C   1 
ATOM   92    O O   . LEU A 1 13  ? 143.686 158.684 164.190 1.00 26.81  ? 38  LEU A O   1 
ATOM   93    C CB  . LEU A 1 13  ? 141.537 160.326 162.240 1.00 26.81  ? 38  LEU A CB  1 
ATOM   94    C CG  . LEU A 1 13  ? 141.663 161.550 163.148 1.00 26.81  ? 38  LEU A CG  1 
ATOM   95    C CD1 . LEU A 1 13  ? 142.717 162.507 162.613 1.00 26.81  ? 38  LEU A CD1 1 
ATOM   96    C CD2 . LEU A 1 13  ? 140.323 162.251 163.295 1.00 26.81  ? 38  LEU A CD2 1 
ATOM   97    N N   . LEU A 1 14  ? 142.159 157.380 163.168 1.00 25.84  ? 39  LEU A N   1 
ATOM   98    C CA  . LEU A 1 14  ? 142.258 156.341 164.187 1.00 25.84  ? 39  LEU A CA  1 
ATOM   99    C C   . LEU A 1 14  ? 143.641 155.704 164.188 1.00 25.84  ? 39  LEU A C   1 
ATOM   100   O O   . LEU A 1 14  ? 144.195 155.404 165.254 1.00 25.84  ? 39  LEU A O   1 
ATOM   101   C CB  . LEU A 1 14  ? 141.175 155.285 163.963 1.00 25.84  ? 39  LEU A CB  1 
ATOM   102   C CG  . LEU A 1 14  ? 141.058 154.182 165.015 1.00 25.84  ? 39  LEU A CG  1 
ATOM   103   C CD1 . LEU A 1 14  ? 139.604 153.967 165.391 1.00 25.84  ? 39  LEU A CD1 1 
ATOM   104   C CD2 . LEU A 1 14  ? 141.676 152.887 164.510 1.00 25.84  ? 39  LEU A CD2 1 
ATOM   105   N N   . GLY A 1 15  ? 144.213 155.483 163.002 1.00 28.88  ? 40  GLY A N   1 
ATOM   106   C CA  . GLY A 1 15  ? 145.566 154.955 162.937 1.00 28.88  ? 40  GLY A CA  1 
ATOM   107   C C   . GLY A 1 15  ? 146.582 155.881 163.578 1.00 28.88  ? 40  GLY A C   1 
ATOM   108   O O   . GLY A 1 15  ? 147.470 155.436 164.311 1.00 28.88  ? 40  GLY A O   1 
ATOM   109   N N   . GLN A 1 16  ? 146.462 157.185 163.311 1.00 29.72  ? 41  GLN A N   1 
ATOM   110   C CA  . GLN A 1 16  ? 147.348 158.162 163.934 1.00 29.72  ? 41  GLN A CA  1 
ATOM   111   C C   . GLN A 1 16  ? 147.202 158.149 165.449 1.00 29.72  ? 41  GLN A C   1 
ATOM   112   O O   . GLN A 1 16  ? 148.202 158.194 166.175 1.00 29.72  ? 41  GLN A O   1 
ATOM   113   C CB  . GLN A 1 16  ? 147.058 159.558 163.382 1.00 29.72  ? 41  GLN A CB  1 
ATOM   114   C CG  . GLN A 1 16  ? 147.586 159.799 161.980 1.00 29.72  ? 41  GLN A CG  1 
ATOM   115   C CD  . GLN A 1 16  ? 147.121 161.122 161.408 1.00 29.72  ? 41  GLN A CD  1 
ATOM   116   O OE1 . GLN A 1 16  ? 147.708 161.642 160.458 1.00 29.72  ? 41  GLN A OE1 1 
ATOM   117   N NE2 . GLN A 1 16  ? 146.061 161.676 161.984 1.00 29.72  ? 41  GLN A NE2 1 
ATOM   118   N N   . LEU A 1 17  ? 145.963 158.093 165.943 1.00 23.74  ? 42  LEU A N   1 
ATOM   119   C CA  . LEU A 1 17  ? 145.740 158.059 167.386 1.00 23.74  ? 42  LEU A CA  1 
ATOM   120   C C   . LEU A 1 17  ? 146.376 156.822 168.012 1.00 23.74  ? 42  LEU A C   1 
ATOM   121   O O   . LEU A 1 17  ? 147.058 156.910 169.042 1.00 23.74  ? 42  LEU A O   1 
ATOM   122   C CB  . LEU A 1 17  ? 144.241 158.102 167.684 1.00 23.74  ? 42  LEU A CB  1 
ATOM   123   C CG  . LEU A 1 17  ? 143.561 159.467 167.573 1.00 23.74  ? 42  LEU A CG  1 
ATOM   124   C CD1 . LEU A 1 17  ? 142.054 159.327 167.710 1.00 23.74  ? 42  LEU A CD1 1 
ATOM   125   C CD2 . LEU A 1 17  ? 144.110 160.421 168.619 1.00 23.74  ? 42  LEU A CD2 1 
ATOM   126   N N   . GLN A 1 18  ? 146.162 155.656 167.397 1.00 21.85  ? 43  GLN A N   1 
ATOM   127   C CA  . GLN A 1 18  ? 146.712 154.419 167.943 1.00 21.85  ? 43  GLN A CA  1 
ATOM   128   C C   . GLN A 1 18  ? 148.235 154.438 167.937 1.00 21.85  ? 43  GLN A C   1 
ATOM   129   O O   . GLN A 1 18  ? 148.872 154.027 168.916 1.00 21.85  ? 43  GLN A O   1 
ATOM   130   C CB  . GLN A 1 18  ? 146.184 153.220 167.157 1.00 21.85  ? 43  GLN A CB  1 
ATOM   131   C CG  . GLN A 1 18  ? 144.722 152.906 167.421 1.00 21.85  ? 43  GLN A CG  1 
ATOM   132   C CD  . GLN A 1 18  ? 144.267 151.632 166.738 1.00 21.85  ? 43  GLN A CD  1 
ATOM   133   O OE1 . GLN A 1 18  ? 143.206 151.091 167.051 1.00 21.85  ? 43  GLN A OE1 1 
ATOM   134   N NE2 . GLN A 1 18  ? 145.068 151.146 165.798 1.00 21.85  ? 43  GLN A NE2 1 
ATOM   135   N N   . LYS A 1 19  ? 148.840 154.916 166.846 1.00 21.81  ? 44  LYS A N   1 
ATOM   136   C CA  . LYS A 1 19  ? 150.297 154.961 166.782 1.00 21.81  ? 44  LYS A CA  1 
ATOM   137   C C   . LYS A 1 19  ? 150.863 155.961 167.783 1.00 21.81  ? 44  LYS A C   1 
ATOM   138   O O   . LYS A 1 19  ? 151.892 155.697 168.416 1.00 21.81  ? 44  LYS A O   1 
ATOM   139   C CB  . LYS A 1 19  ? 150.751 155.292 165.361 1.00 21.81  ? 44  LYS A CB  1 
ATOM   140   C CG  . LYS A 1 19  ? 150.538 154.152 164.376 1.00 21.81  ? 44  LYS A CG  1 
ATOM   141   C CD  . LYS A 1 19  ? 151.529 154.211 163.227 1.00 21.81  ? 44  LYS A CD  1 
ATOM   142   C CE  . LYS A 1 19  ? 151.458 152.956 162.373 1.00 21.81  ? 44  LYS A CE  1 
ATOM   143   N NZ  . LYS A 1 19  ? 152.472 152.970 161.283 1.00 21.81  ? 44  LYS A NZ  1 
ATOM   144   N N   . GLN A 1 20  ? 150.197 157.107 167.956 1.00 29.63  ? 45  GLN A N   1 
ATOM   145   C CA  . GLN A 1 20  ? 150.643 158.078 168.948 1.00 29.63  ? 45  GLN A CA  1 
ATOM   146   C C   . GLN A 1 20  ? 150.578 157.500 170.354 1.00 29.63  ? 45  GLN A C   1 
ATOM   147   O O   . GLN A 1 20  ? 151.488 157.712 171.164 1.00 29.63  ? 45  GLN A O   1 
ATOM   148   C CB  . GLN A 1 20  ? 149.799 159.349 168.856 1.00 29.63  ? 45  GLN A CB  1 
ATOM   149   C CG  . GLN A 1 20  ? 150.338 160.392 167.896 1.00 29.63  ? 45  GLN A CG  1 
ATOM   150   C CD  . GLN A 1 20  ? 149.527 161.671 167.921 1.00 29.63  ? 45  GLN A CD  1 
ATOM   151   O OE1 . GLN A 1 20  ? 148.300 161.640 168.006 1.00 29.63  ? 45  GLN A OE1 1 
ATOM   152   N NE2 . GLN A 1 20  ? 150.211 162.807 167.852 1.00 29.63  ? 45  GLN A NE2 1 
ATOM   153   N N   . THR A 1 21  ? 149.509 156.761 170.665 1.00 21.33  ? 46  THR A N   1 
ATOM   154   C CA  . THR A 1 21  ? 149.401 156.164 171.992 1.00 21.33  ? 46  THR A CA  1 
ATOM   155   C C   . THR A 1 21  ? 150.468 155.096 172.207 1.00 21.33  ? 46  THR A C   1 
ATOM   156   O O   . THR A 1 21  ? 151.094 155.038 173.275 1.00 21.33  ? 46  THR A O   1 
ATOM   157   C CB  . THR A 1 21  ? 148.007 155.575 172.193 1.00 21.33  ? 46  THR A CB  1 
ATOM   158   O OG1 . THR A 1 21  ? 147.021 156.539 171.803 1.00 21.33  ? 46  THR A OG1 1 
ATOM   159   C CG2 . THR A 1 21  ? 147.797 155.214 173.650 1.00 21.33  ? 46  THR A CG2 1 
ATOM   160   N N   . ASP A 1 22  ? 150.693 154.245 171.203 1.00 30.83  ? 47  ASP A N   1 
ATOM   161   C CA  . ASP A 1 22  ? 151.720 153.216 171.329 1.00 30.83  ? 47  ASP A CA  1 
ATOM   162   C C   . ASP A 1 22  ? 153.112 153.824 171.438 1.00 30.83  ? 47  ASP A C   1 
ATOM   163   O O   . ASP A 1 22  ? 154.003 153.226 172.051 1.00 30.83  ? 47  ASP A O   1 
ATOM   164   C CB  . ASP A 1 22  ? 151.648 152.253 170.144 1.00 30.83  ? 47  ASP A CB  1 
ATOM   165   C CG  . ASP A 1 22  ? 150.332 151.503 170.083 1.00 30.83  ? 47  ASP A CG  1 
ATOM   166   O OD1 . ASP A 1 22  ? 149.699 151.324 171.145 1.00 30.83  ? 47  ASP A OD1 1 
ATOM   167   O OD2 . ASP A 1 22  ? 149.931 151.092 168.974 1.00 30.83  ? 47  ASP A OD2 1 
ATOM   168   N N   . LEU A 1 23  ? 153.320 155.005 170.853 1.00 33.01  ? 48  LEU A N   1 
ATOM   169   C CA  . LEU A 1 23  ? 154.610 155.674 170.976 1.00 33.01  ? 48  LEU A CA  1 
ATOM   170   C C   . LEU A 1 23  ? 154.771 156.337 172.339 1.00 33.01  ? 48  LEU A C   1 
ATOM   171   O O   . LEU A 1 23  ? 155.861 156.306 172.922 1.00 33.01  ? 48  LEU A O   1 
ATOM   172   C CB  . LEU A 1 23  ? 154.773 156.703 169.856 1.00 33.01  ? 48  LEU A CB  1 
ATOM   173   C CG  . LEU A 1 23  ? 156.156 157.332 169.678 1.00 33.01  ? 48  LEU A CG  1 
ATOM   174   C CD1 . LEU A 1 23  ? 156.522 157.400 168.205 1.00 33.01  ? 48  LEU A CD1 1 
ATOM   175   C CD2 . LEU A 1 23  ? 156.203 158.718 170.304 1.00 33.01  ? 48  LEU A CD2 1 
ATOM   176   N N   . MET A 1 24  ? 153.703 156.940 172.862 1.00 42.82  ? 49  MET A N   1 
ATOM   177   C CA  . MET A 1 24  ? 153.762 157.623 174.148 1.00 42.82  ? 49  MET A CA  1 
ATOM   178   C C   . MET A 1 24  ? 153.692 156.671 175.335 1.00 42.82  ? 49  MET A C   1 
ATOM   179   O O   . MET A 1 24  ? 153.932 157.104 176.467 1.00 42.82  ? 49  MET A O   1 
ATOM   180   C CB  . MET A 1 24  ? 152.631 158.650 174.249 1.00 42.82  ? 49  MET A CB  1 
ATOM   181   C CG  . MET A 1 24  ? 152.769 159.820 173.288 1.00 42.82  ? 49  MET A CG  1 
ATOM   182   S SD  . MET A 1 24  ? 151.324 160.897 173.292 1.00 42.82  ? 49  MET A SD  1 
ATOM   183   C CE  . MET A 1 24  ? 151.281 161.400 175.009 1.00 42.82  ? 49  MET A CE  1 
ATOM   184   N N   . GLN A 1 25  ? 153.374 155.397 175.109 1.00 29.87  ? 50  GLN A N   1 
ATOM   185   C CA  . GLN A 1 25  ? 153.349 154.411 176.184 1.00 29.87  ? 50  GLN A CA  1 
ATOM   186   C C   . GLN A 1 25  ? 154.741 153.864 176.532 1.00 29.87  ? 50  GLN A C   1 
ATOM   187   O O   . GLN A 1 25  ? 154.839 152.785 177.127 1.00 29.87  ? 50  GLN A O   1 
ATOM   188   C CB  . GLN A 1 25  ? 152.413 153.259 175.808 1.00 29.87  ? 50  GLN A CB  1 
ATOM   189   C CG  . GLN A 1 25  ? 151.754 152.562 176.988 1.00 29.87  ? 50  GLN A CG  1 
ATOM   190   C CD  . GLN A 1 25  ? 151.130 151.238 176.599 1.00 29.87  ? 50  GLN A CD  1 
ATOM   191   O OE1 . GLN A 1 25  ? 150.496 151.122 175.550 1.00 29.87  ? 50  GLN A OE1 1 
ATOM   192   N NE2 . GLN A 1 25  ? 151.315 150.227 177.439 1.00 29.87  ? 50  GLN A NE2 1 
ATOM   193   N N   . ASP A 1 26  ? 155.811 154.575 176.181 1.00 42.63  ? 51  ASP A N   1 
ATOM   194   C CA  . ASP A 1 26  ? 157.176 154.076 176.356 1.00 42.63  ? 51  ASP A CA  1 
ATOM   195   C C   . ASP A 1 26  ? 157.671 154.406 177.761 1.00 42.63  ? 51  ASP A C   1 
ATOM   196   O O   . ASP A 1 26  ? 158.073 155.541 178.050 1.00 42.63  ? 51  ASP A O   1 
ATOM   197   C CB  . ASP A 1 26  ? 158.095 154.657 175.289 1.00 42.63  ? 51  ASP A CB  1 
ATOM   198   C CG  . ASP A 1 26  ? 158.100 153.836 174.015 1.00 42.63  ? 51  ASP A CG  1 
ATOM   199   O OD1 . ASP A 1 26  ? 158.057 152.591 174.110 1.00 42.63  ? 51  ASP A OD1 1 
ATOM   200   O OD2 . ASP A 1 26  ? 158.145 154.435 172.920 1.00 42.63  ? 51  ASP A OD2 1 
ATOM   201   N N   . THR A 1 27  ? 157.659 153.395 178.635 1.00 45.52  ? 52  THR A N   1 
ATOM   202   C CA  . THR A 1 27  ? 158.162 153.576 179.993 1.00 45.52  ? 52  THR A CA  1 
ATOM   203   C C   . THR A 1 27  ? 159.649 153.899 179.985 1.00 45.52  ? 52  THR A C   1 
ATOM   204   O O   . THR A 1 27  ? 160.092 154.841 180.650 1.00 45.52  ? 52  THR A O   1 
ATOM   205   C CB  . THR A 1 27  ? 157.888 152.324 180.828 1.00 45.52  ? 52  THR A CB  1 
ATOM   206   O OG1 . THR A 1 27  ? 158.594 151.210 180.268 1.00 45.52  ? 52  THR A OG1 1 
ATOM   207   C CG2 . THR A 1 27  ? 156.399 152.015 180.851 1.00 45.52  ? 52  THR A CG2 1 
ATOM   208   N N   . SER A 1 28  ? 160.436 153.135 179.222 1.00 33.68  ? 53  SER A N   1 
ATOM   209   C CA  . SER A 1 28  ? 161.872 153.377 179.152 1.00 33.68  ? 53  SER A CA  1 
ATOM   210   C C   . SER A 1 28  ? 162.202 154.743 178.566 1.00 33.68  ? 53  SER A C   1 
ATOM   211   O O   . SER A 1 28  ? 163.304 155.253 178.795 1.00 33.68  ? 53  SER A O   1 
ATOM   212   C CB  . SER A 1 28  ? 162.550 152.282 178.326 1.00 33.68  ? 53  SER A CB  1 
ATOM   213   O OG  . SER A 1 28  ? 163.805 152.719 177.834 1.00 33.68  ? 53  SER A OG  1 
ATOM   214   N N   . ARG A 1 29  ? 161.280 155.344 177.817 1.00 33.67  ? 54  ARG A N   1 
ATOM   215   C CA  . ARG A 1 29  ? 161.506 156.671 177.262 1.00 33.67  ? 54  ARG A CA  1 
ATOM   216   C C   . ARG A 1 29  ? 161.059 157.786 178.193 1.00 33.67  ? 54  ARG A C   1 
ATOM   217   O O   . ARG A 1 29  ? 161.635 158.880 178.152 1.00 33.67  ? 54  ARG A O   1 
ATOM   218   C CB  . ARG A 1 29  ? 160.780 156.822 175.922 1.00 33.67  ? 54  ARG A CB  1 
ATOM   219   C CG  . ARG A 1 29  ? 161.512 156.229 174.730 1.00 33.67  ? 54  ARG A CG  1 
ATOM   220   C CD  . ARG A 1 29  ? 160.707 156.421 173.454 1.00 33.67  ? 54  ARG A CD  1 
ATOM   221   N NE  . ARG A 1 29  ? 161.391 155.887 172.281 1.00 33.67  ? 54  ARG A NE  1 
ATOM   222   C CZ  . ARG A 1 29  ? 162.013 156.634 171.375 1.00 33.67  ? 54  ARG A CZ  1 
ATOM   223   N NH1 . ARG A 1 29  ? 162.037 157.953 171.505 1.00 33.67  ? 54  ARG A NH1 1 
ATOM   224   N NH2 . ARG A 1 29  ? 162.610 156.063 170.338 1.00 33.67  ? 54  ARG A NH2 1 
ATOM   225   N N   . LEU A 1 30  ? 160.042 157.551 179.024 1.00 28.40  ? 55  LEU A N   1 
ATOM   226   C CA  . LEU A 1 30  ? 159.509 158.619 179.868 1.00 28.40  ? 55  LEU A CA  1 
ATOM   227   C C   . LEU A 1 30  ? 159.934 158.503 181.330 1.00 28.40  ? 55  LEU A C   1 
ATOM   228   O O   . LEU A 1 30  ? 160.507 159.446 181.885 1.00 28.40  ? 55  LEU A O   1 
ATOM   229   C CB  . LEU A 1 30  ? 157.981 158.653 179.762 1.00 28.40  ? 55  LEU A CB  1 
ATOM   230   C CG  . LEU A 1 30  ? 157.304 159.740 180.595 1.00 28.40  ? 55  LEU A CG  1 
ATOM   231   C CD1 . LEU A 1 30  ? 157.826 161.115 180.209 1.00 28.40  ? 55  LEU A CD1 1 
ATOM   232   C CD2 . LEU A 1 30  ? 155.801 159.670 180.427 1.00 28.40  ? 55  LEU A CD2 1 
ATOM   233   N N   . LEU A 1 31  ? 159.665 157.364 181.970 1.00 22.03  ? 56  LEU A N   1 
ATOM   234   C CA  . LEU A 1 31  ? 159.860 157.262 183.414 1.00 22.03  ? 56  LEU A CA  1 
ATOM   235   C C   . LEU A 1 31  ? 161.324 157.039 183.774 1.00 22.03  ? 56  LEU A C   1 
ATOM   236   O O   . LEU A 1 31  ? 161.859 157.712 184.662 1.00 22.03  ? 56  LEU A O   1 
ATOM   237   C CB  . LEU A 1 31  ? 158.994 156.137 183.982 1.00 22.03  ? 56  LEU A CB  1 
ATOM   238   C CG  . LEU A 1 31  ? 159.230 155.762 185.448 1.00 22.03  ? 56  LEU A CG  1 
ATOM   239   C CD1 . LEU A 1 31  ? 159.031 156.964 186.355 1.00 22.03  ? 56  LEU A CD1 1 
ATOM   240   C CD2 . LEU A 1 31  ? 158.315 154.620 185.864 1.00 22.03  ? 56  LEU A CD2 1 
ATOM   241   N N   . ASP A 1 32  ? 161.979 156.088 183.109 1.00 27.57  ? 57  ASP A N   1 
ATOM   242   C CA  . ASP A 1 32  ? 163.375 155.791 183.424 1.00 27.57  ? 57  ASP A CA  1 
ATOM   243   C C   . ASP A 1 32  ? 164.300 156.999 183.300 1.00 27.57  ? 57  ASP A C   1 
ATOM   244   O O   . ASP A 1 32  ? 165.187 157.145 184.159 1.00 27.57  ? 57  ASP A O   1 
ATOM   245   C CB  . ASP A 1 32  ? 163.867 154.636 182.542 1.00 27.57  ? 57  ASP A CB  1 
ATOM   246   C CG  . ASP A 1 32  ? 165.145 154.009 183.062 1.00 27.57  ? 57  ASP A CG  1 
ATOM   247   O OD1 . ASP A 1 32  ? 165.511 154.278 184.225 1.00 27.57  ? 57  ASP A OD1 1 
ATOM   248   O OD2 . ASP A 1 32  ? 165.784 153.248 182.306 1.00 27.57  ? 57  ASP A OD2 1 
ATOM   249   N N   . PRO A 1 33  ? 164.179 157.870 182.288 1.00 24.89  ? 58  PRO A N   1 
ATOM   250   C CA  . PRO A 1 33  ? 165.011 159.085 182.290 1.00 24.89  ? 58  PRO A CA  1 
ATOM   251   C C   . PRO A 1 33  ? 164.832 159.940 183.531 1.00 24.89  ? 58  PRO A C   1 
ATOM   252   O O   . PRO A 1 33  ? 165.809 160.510 184.031 1.00 24.89  ? 58  PRO A O   1 
ATOM   253   C CB  . PRO A 1 33  ? 164.549 159.814 181.023 1.00 24.89  ? 58  PRO A CB  1 
ATOM   254   C CG  . PRO A 1 33  ? 164.129 158.727 180.120 1.00 24.89  ? 58  PRO A CG  1 
ATOM   255   C CD  . PRO A 1 33  ? 163.461 157.719 181.009 1.00 24.89  ? 58  PRO A CD  1 
ATOM   256   N N   . TYR A 1 34  ? 163.607 160.036 184.053 1.00 21.03  ? 59  TYR A N   1 
ATOM   257   C CA  . TYR A 1 34  ? 163.368 160.840 185.247 1.00 21.03  ? 59  TYR A CA  1 
ATOM   258   C C   . TYR A 1 34  ? 164.095 160.261 186.456 1.00 21.03  ? 59  TYR A C   1 
ATOM   259   O O   . TYR A 1 34  ? 164.773 160.988 187.193 1.00 21.03  ? 59  TYR A O   1 
ATOM   260   C CB  . TYR A 1 34  ? 161.865 160.936 185.511 1.00 21.03  ? 59  TYR A CB  1 
ATOM   261   C CG  . TYR A 1 34  ? 161.497 161.506 186.863 1.00 21.03  ? 59  TYR A CG  1 
ATOM   262   C CD1 . TYR A 1 34  ? 161.521 162.874 187.091 1.00 21.03  ? 59  TYR A CD1 1 
ATOM   263   C CD2 . TYR A 1 34  ? 161.112 160.674 187.907 1.00 21.03  ? 59  TYR A CD2 1 
ATOM   264   C CE1 . TYR A 1 34  ? 161.180 163.399 188.323 1.00 21.03  ? 59  TYR A CE1 1 
ATOM   265   C CE2 . TYR A 1 34  ? 160.771 161.189 189.143 1.00 21.03  ? 59  TYR A CE2 1 
ATOM   266   C CZ  . TYR A 1 34  ? 160.806 162.552 189.345 1.00 21.03  ? 59  TYR A CZ  1 
ATOM   267   O OH  . TYR A 1 34  ? 160.467 163.070 190.572 1.00 21.03  ? 59  TYR A OH  1 
ATOM   268   N N   . ILE A 1 35  ? 163.966 158.950 186.673 1.00 19.97  ? 60  ILE A N   1 
ATOM   269   C CA  . ILE A 1 35  ? 164.637 158.318 187.803 1.00 19.97  ? 60  ILE A CA  1 
ATOM   270   C C   . ILE A 1 35  ? 166.149 158.383 187.639 1.00 19.97  ? 60  ILE A C   1 
ATOM   271   O O   . ILE A 1 35  ? 166.884 158.498 188.628 1.00 19.97  ? 60  ILE A O   1 
ATOM   272   C CB  . ILE A 1 35  ? 164.148 156.868 187.968 1.00 19.97  ? 60  ILE A CB  1 
ATOM   273   C CG1 . ILE A 1 35  ? 162.619 156.824 187.992 1.00 19.97  ? 60  ILE A CG1 1 
ATOM   274   C CG2 . ILE A 1 35  ? 164.714 156.251 189.236 1.00 19.97  ? 60  ILE A CG2 1 
ATOM   275   C CD1 . ILE A 1 35  ? 162.050 155.428 188.115 1.00 19.97  ? 60  ILE A CD1 1 
ATOM   276   N N   . ARG A 1 36  ? 166.642 158.320 186.401 1.00 41.45  ? 61  ARG A N   1 
ATOM   277   C CA  . ARG A 1 36  ? 168.082 158.405 186.180 1.00 41.45  ? 61  ARG A CA  1 
ATOM   278   C C   . ARG A 1 36  ? 168.602 159.811 186.453 1.00 41.45  ? 61  ARG A C   1 
ATOM   279   O O   . ARG A 1 36  ? 169.687 159.979 187.021 1.00 41.45  ? 61  ARG A O   1 
ATOM   280   C CB  . ARG A 1 36  ? 168.417 157.971 184.753 1.00 41.45  ? 61  ARG A CB  1 
ATOM   281   C CG  . ARG A 1 36  ? 169.868 158.184 184.356 1.00 41.45  ? 61  ARG A CG  1 
ATOM   282   C CD  . ARG A 1 36  ? 170.272 157.275 183.204 1.00 41.45  ? 61  ARG A CD  1 
ATOM   283   N NE  . ARG A 1 36  ? 169.360 157.378 182.069 1.00 41.45  ? 61  ARG A NE  1 
ATOM   284   C CZ  . ARG A 1 36  ? 168.487 156.437 181.723 1.00 41.45  ? 61  ARG A CZ  1 
ATOM   285   N NH1 . ARG A 1 36  ? 168.405 155.316 182.427 1.00 41.45  ? 61  ARG A NH1 1 
ATOM   286   N NH2 . ARG A 1 36  ? 167.696 156.615 180.674 1.00 41.45  ? 61  ARG A NH2 1 
ATOM   287   N N   . ILE A 1 37  ? 167.839 160.834 186.062 1.00 15.97  ? 62  ILE A N   1 
ATOM   288   C CA  . ILE A 1 37  ? 168.285 162.210 186.249 1.00 15.97  ? 62  ILE A CA  1 
ATOM   289   C C   . ILE A 1 37  ? 168.058 162.704 187.672 1.00 15.97  ? 62  ILE A C   1 
ATOM   290   O O   . ILE A 1 37  ? 168.687 163.687 188.085 1.00 15.97  ? 62  ILE A O   1 
ATOM   291   C CB  . ILE A 1 37  ? 167.587 163.137 185.239 1.00 15.97  ? 62  ILE A CB  1 
ATOM   292   C CG1 . ILE A 1 37  ? 168.420 164.396 184.993 1.00 15.97  ? 62  ILE A CG1 1 
ATOM   293   C CG2 . ILE A 1 37  ? 166.190 163.507 185.716 1.00 15.97  ? 62  ILE A CG2 1 
ATOM   294   C CD1 . ILE A 1 37  ? 167.767 165.375 184.044 1.00 15.97  ? 62  ILE A CD1 1 
ATOM   295   N N   . GLN A 1 38  ? 167.184 162.055 188.438 1.00 36.67  ? 63  GLN A N   1 
ATOM   296   C CA  . GLN A 1 38  ? 166.913 162.467 189.808 1.00 36.67  ? 63  GLN A CA  1 
ATOM   297   C C   . GLN A 1 38  ? 167.861 161.840 190.821 1.00 36.67  ? 63  GLN A C   1 
ATOM   298   O O   . GLN A 1 38  ? 167.690 162.060 192.025 1.00 36.67  ? 63  GLN A O   1 
ATOM   299   C CB  . GLN A 1 38  ? 165.466 162.133 190.185 1.00 36.67  ? 63  GLN A CB  1 
ATOM   300   C CG  . GLN A 1 38  ? 164.442 163.109 189.633 1.00 36.67  ? 63  GLN A CG  1 
ATOM   301   C CD  . GLN A 1 38  ? 164.497 164.462 190.313 1.00 36.67  ? 63  GLN A CD  1 
ATOM   302   O OE1 . GLN A 1 38  ? 165.064 164.604 191.396 1.00 36.67  ? 63  GLN A OE1 1 
ATOM   303   N NE2 . GLN A 1 38  ? 163.906 165.467 189.678 1.00 36.67  ? 63  GLN A NE2 1 
ATOM   304   N N   . GLY A 1 39  ? 168.848 161.068 190.372 1.00 23.04  ? 64  GLY A N   1 
ATOM   305   C CA  . GLY A 1 39  ? 169.786 160.450 191.287 1.00 23.04  ? 64  GLY A CA  1 
ATOM   306   C C   . GLY A 1 39  ? 169.254 159.262 192.053 1.00 23.04  ? 64  GLY A C   1 
ATOM   307   O O   . GLY A 1 39  ? 169.905 158.815 193.002 1.00 23.04  ? 64  GLY A O   1 
ATOM   308   N N   . LEU A 1 40  ? 168.089 158.734 191.675 1.00 24.51  ? 65  LEU A N   1 
ATOM   309   C CA  . LEU A 1 40  ? 167.489 157.582 192.337 1.00 24.51  ? 65  LEU A CA  1 
ATOM   310   C C   . LEU A 1 40  ? 167.747 156.283 191.581 1.00 24.51  ? 65  LEU A C   1 
ATOM   311   O O   . LEU A 1 40  ? 166.910 155.375 191.601 1.00 24.51  ? 65  LEU A O   1 
ATOM   312   C CB  . LEU A 1 40  ? 165.987 157.799 192.519 1.00 24.51  ? 65  LEU A CB  1 
ATOM   313   C CG  . LEU A 1 40  ? 165.534 159.189 192.970 1.00 24.51  ? 65  LEU A CG  1 
ATOM   314   C CD1 . LEU A 1 40  ? 164.022 159.236 193.119 1.00 24.51  ? 65  LEU A CD1 1 
ATOM   315   C CD2 . LEU A 1 40  ? 166.213 159.585 194.271 1.00 24.51  ? 65  LEU A CD2 1 
ATOM   316   N N   . ASP A 1 41  ? 168.897 156.176 190.913 1.00 36.31  ? 66  ASP A N   1 
ATOM   317   C CA  . ASP A 1 41  ? 169.212 155.015 190.082 1.00 36.31  ? 66  ASP A CA  1 
ATOM   318   C C   . ASP A 1 41  ? 169.780 153.872 190.929 1.00 36.31  ? 66  ASP A C   1 
ATOM   319   O O   . ASP A 1 41  ? 170.877 153.363 190.700 1.00 36.31  ? 66  ASP A O   1 
ATOM   320   C CB  . ASP A 1 41  ? 170.176 155.414 188.972 1.00 36.31  ? 66  ASP A CB  1 
ATOM   321   C CG  . ASP A 1 41  ? 171.321 156.270 189.475 1.00 36.31  ? 66  ASP A CG  1 
ATOM   322   O OD1 . ASP A 1 41  ? 171.341 156.589 190.682 1.00 36.31  ? 66  ASP A OD1 1 
ATOM   323   O OD2 . ASP A 1 41  ? 172.202 156.625 188.663 1.00 36.31  ? 66  ASP A OD2 1 
ATOM   324   N N   . VAL A 1 42  ? 169.000 153.471 191.928 1.00 36.76  ? 67  VAL A N   1 
ATOM   325   C CA  . VAL A 1 42  ? 169.334 152.323 192.768 1.00 36.76  ? 67  VAL A CA  1 
ATOM   326   C C   . VAL A 1 42  ? 168.092 151.448 192.901 1.00 36.76  ? 67  VAL A C   1 
ATOM   327   O O   . VAL A 1 42  ? 166.967 151.969 192.895 1.00 36.76  ? 67  VAL A O   1 
ATOM   328   C CB  . VAL A 1 42  ? 169.866 152.762 194.142 1.00 36.76  ? 67  VAL A CB  1 
ATOM   329   C CG1 . VAL A 1 42  ? 171.222 153.439 193.999 1.00 36.76  ? 67  VAL A CG1 1 
ATOM   330   C CG2 . VAL A 1 42  ? 168.882 153.695 194.819 1.00 36.76  ? 67  VAL A CG2 1 
ATOM   331   N N   . PRO A 1 43  ? 168.244 150.125 193.008 1.00 41.27  ? 68  PRO A N   1 
ATOM   332   C CA  . PRO A 1 43  ? 167.055 149.257 193.045 1.00 41.27  ? 68  PRO A CA  1 
ATOM   333   C C   . PRO A 1 43  ? 166.186 149.470 194.271 1.00 41.27  ? 68  PRO A C   1 
ATOM   334   O O   . PRO A 1 43  ? 164.956 149.390 194.162 1.00 41.27  ? 68  PRO A O   1 
ATOM   335   C CB  . PRO A 1 43  ? 167.649 147.841 193.017 1.00 41.27  ? 68  PRO A CB  1 
ATOM   336   C CG  . PRO A 1 43  ? 169.050 148.012 192.506 1.00 41.27  ? 68  PRO A CG  1 
ATOM   337   C CD  . PRO A 1 43  ? 169.495 149.350 193.003 1.00 41.27  ? 68  PRO A CD  1 
ATOM   338   N N   . LYS A 1 44  ? 166.785 149.737 195.434 1.00 49.58  ? 69  LYS A N   1 
ATOM   339   C CA  . LYS A 1 44  ? 165.998 149.925 196.648 1.00 49.58  ? 69  LYS A CA  1 
ATOM   340   C C   . LYS A 1 44  ? 165.054 151.113 196.512 1.00 49.58  ? 69  LYS A C   1 
ATOM   341   O O   . LYS A 1 44  ? 163.866 151.019 196.844 1.00 49.58  ? 69  LYS A O   1 
ATOM   342   C CB  . LYS A 1 44  ? 166.924 150.104 197.851 1.00 49.58  ? 69  LYS A CB  1 
ATOM   343   C CG  . LYS A 1 44  ? 166.195 150.368 199.159 1.00 49.58  ? 69  LYS A CG  1 
ATOM   344   C CD  . LYS A 1 44  ? 165.259 149.224 199.513 1.00 49.58  ? 69  LYS A CD  1 
ATOM   345   C CE  . LYS A 1 44  ? 166.030 147.938 199.760 1.00 49.58  ? 69  LYS A CE  1 
ATOM   346   N NZ  . LYS A 1 44  ? 165.122 146.802 200.079 1.00 49.58  ? 69  LYS A NZ  1 
ATOM   347   N N   . LEU A 1 45  ? 165.564 152.243 196.021 1.00 38.73  ? 70  LEU A N   1 
ATOM   348   C CA  . LEU A 1 45  ? 164.713 153.412 195.831 1.00 38.73  ? 70  LEU A CA  1 
ATOM   349   C C   . LEU A 1 45  ? 163.802 153.261 194.620 1.00 38.73  ? 70  LEU A C   1 
ATOM   350   O O   . LEU A 1 45  ? 162.734 153.881 194.575 1.00 38.73  ? 70  LEU A O   1 
ATOM   351   C CB  . LEU A 1 45  ? 165.566 154.674 195.690 1.00 38.73  ? 70  LEU A CB  1 
ATOM   352   C CG  . LEU A 1 45  ? 165.946 155.408 196.979 1.00 38.73  ? 70  LEU A CG  1 
ATOM   353   C CD1 . LEU A 1 45  ? 166.945 154.607 197.800 1.00 38.73  ? 70  LEU A CD1 1 
ATOM   354   C CD2 . LEU A 1 45  ? 166.496 156.790 196.666 1.00 38.73  ? 70  LEU A CD2 1 
ATOM   355   N N   . ARG A 1 46  ? 164.199 152.450 193.637 1.00 40.19  ? 71  ARG A N   1 
ATOM   356   C CA  . ARG A 1 46  ? 163.342 152.233 192.478 1.00 40.19  ? 71  ARG A CA  1 
ATOM   357   C C   . ARG A 1 46  ? 162.138 151.367 192.827 1.00 40.19  ? 71  ARG A C   1 
ATOM   358   O O   . ARG A 1 46  ? 161.078 151.503 192.206 1.00 40.19  ? 71  ARG A O   1 
ATOM   359   C CB  . ARG A 1 46  ? 164.144 151.598 191.342 1.00 40.19  ? 71  ARG A CB  1 
ATOM   360   C CG  . ARG A 1 46  ? 163.384 151.486 190.029 1.00 40.19  ? 71  ARG A CG  1 
ATOM   361   C CD  . ARG A 1 46  ? 164.226 150.820 188.954 1.00 40.19  ? 71  ARG A CD  1 
ATOM   362   N NE  . ARG A 1 46  ? 163.475 150.635 187.716 1.00 40.19  ? 71  ARG A NE  1 
ATOM   363   C CZ  . ARG A 1 46  ? 163.383 151.548 186.755 1.00 40.19  ? 71  ARG A CZ  1 
ATOM   364   N NH1 . ARG A 1 46  ? 163.998 152.715 186.886 1.00 40.19  ? 71  ARG A NH1 1 
ATOM   365   N NH2 . ARG A 1 46  ? 162.675 151.295 185.663 1.00 40.19  ? 71  ARG A NH2 1 
ATOM   366   N N   . GLU A 1 47  ? 162.279 150.481 193.814 1.00 51.52  ? 72  GLU A N   1 
ATOM   367   C CA  . GLU A 1 47  ? 161.174 149.620 194.219 1.00 51.52  ? 72  GLU A CA  1 
ATOM   368   C C   . GLU A 1 47  ? 160.004 150.393 194.810 1.00 51.52  ? 72  GLU A C   1 
ATOM   369   O O   . GLU A 1 47  ? 158.899 149.846 194.885 1.00 51.52  ? 72  GLU A O   1 
ATOM   370   C CB  . GLU A 1 47  ? 161.662 148.582 195.230 1.00 51.52  ? 72  GLU A CB  1 
ATOM   371   C CG  . GLU A 1 47  ? 162.410 147.418 194.612 1.00 51.52  ? 72  GLU A CG  1 
ATOM   372   C CD  . GLU A 1 47  ? 163.063 146.529 195.651 1.00 51.52  ? 72  GLU A CD  1 
ATOM   373   O OE1 . GLU A 1 47  ? 163.433 147.042 196.728 1.00 51.52  ? 72  GLU A OE1 1 
ATOM   374   O OE2 . GLU A 1 47  ? 163.210 145.318 195.390 1.00 51.52  ? 72  GLU A OE2 1 
ATOM   375   N N   . HIS A 1 48  ? 160.211 151.642 195.224 1.00 65.35  ? 73  HIS A N   1 
ATOM   376   C CA  . HIS A 1 48  ? 159.147 152.432 195.827 1.00 65.35  ? 73  HIS A CA  1 
ATOM   377   C C   . HIS A 1 48  ? 158.464 153.377 194.847 1.00 65.35  ? 73  HIS A C   1 
ATOM   378   O O   . HIS A 1 48  ? 157.386 153.890 195.161 1.00 65.35  ? 73  HIS A O   1 
ATOM   379   C CB  . HIS A 1 48  ? 159.694 153.238 197.010 1.00 65.35  ? 73  HIS A CB  1 
ATOM   380   C CG  . HIS A 1 48  ? 160.227 152.391 198.124 1.00 65.35  ? 73  HIS A CG  1 
ATOM   381   N ND1 . HIS A 1 48  ? 159.412 151.788 199.058 1.00 65.35  ? 73  HIS A ND1 1 
ATOM   382   C CD2 . HIS A 1 48  ? 161.495 152.053 198.457 1.00 65.35  ? 73  HIS A CD2 1 
ATOM   383   C CE1 . HIS A 1 48  ? 160.155 151.112 199.916 1.00 65.35  ? 73  HIS A CE1 1 
ATOM   384   N NE2 . HIS A 1 48  ? 161.422 151.256 199.574 1.00 65.35  ? 73  HIS A NE2 1 
ATOM   385   N N   . CYS A 1 49  ? 159.053 153.621 193.676 1.00 62.16  ? 74  CYS A N   1 
ATOM   386   C CA  . CYS A 1 49  ? 158.448 154.501 192.675 1.00 62.16  ? 74  CYS A CA  1 
ATOM   387   C C   . CYS A 1 49  ? 157.295 153.750 192.011 1.00 62.16  ? 74  CYS A C   1 
ATOM   388   O O   . CYS A 1 49  ? 157.398 153.236 190.894 1.00 62.16  ? 74  CYS A O   1 
ATOM   389   C CB  . CYS A 1 49  ? 159.487 154.962 191.658 1.00 62.16  ? 74  CYS A CB  1 
ATOM   390   S SG  . CYS A 1 49  ? 160.802 156.038 192.319 1.00 62.16  ? 74  CYS A SG  1 
ATOM   391   N N   . ARG A 1 50  ? 156.175 153.687 192.729 1.00 56.59  ? 75  ARG A N   1 
ATOM   392   C CA  . ARG A 1 50  ? 154.988 152.966 192.295 1.00 56.59  ? 75  ARG A CA  1 
ATOM   393   C C   . ARG A 1 50  ? 153.790 153.905 192.255 1.00 56.59  ? 75  ARG A C   1 
ATOM   394   O O   . ARG A 1 50  ? 153.822 155.005 192.813 1.00 56.59  ? 75  ARG A O   1 
ATOM   395   C CB  . ARG A 1 50  ? 154.685 151.783 193.224 1.00 56.59  ? 75  ARG A CB  1 
ATOM   396   C CG  . ARG A 1 50  ? 155.870 150.864 193.478 1.00 56.59  ? 75  ARG A CG  1 
ATOM   397   C CD  . ARG A 1 50  ? 155.410 149.445 193.770 1.00 56.59  ? 75  ARG A CD  1 
ATOM   398   N NE  . ARG A 1 50  ? 154.752 148.836 192.617 1.00 56.59  ? 75  ARG A NE  1 
ATOM   399   C CZ  . ARG A 1 50  ? 155.384 148.137 191.680 1.00 56.59  ? 75  ARG A CZ  1 
ATOM   400   N NH1 . ARG A 1 50  ? 154.705 147.619 190.665 1.00 56.59  ? 75  ARG A NH1 1 
ATOM   401   N NH2 . ARG A 1 50  ? 156.695 147.953 191.756 1.00 56.59  ? 75  ARG A NH2 1 
ATOM   402   N N   . GLU A 1 51  ? 152.728 153.456 191.590 1.00 61.67  ? 76  GLU A N   1 
ATOM   403   C CA  . GLU A 1 51  ? 151.521 154.262 191.473 1.00 61.67  ? 76  GLU A CA  1 
ATOM   404   C C   . GLU A 1 51  ? 150.704 154.194 192.758 1.00 61.67  ? 76  GLU A C   1 
ATOM   405   O O   . GLU A 1 51  ? 150.529 153.119 193.340 1.00 61.67  ? 76  GLU A O   1 
ATOM   406   C CB  . GLU A 1 51  ? 150.679 153.788 190.290 1.00 61.67  ? 76  GLU A CB  1 
ATOM   407   C CG  . GLU A 1 51  ? 149.330 154.479 190.167 1.00 61.67  ? 76  GLU A CG  1 
ATOM   408   C CD  . GLU A 1 51  ? 148.445 153.838 189.119 1.00 61.67  ? 76  GLU A CD  1 
ATOM   409   O OE1 . GLU A 1 51  ? 148.828 152.777 188.584 1.00 61.67  ? 76  GLU A OE1 1 
ATOM   410   O OE2 . GLU A 1 51  ? 147.367 154.396 188.829 1.00 61.67  ? 76  GLU A OE2 1 
ATOM   411   N N   . ARG A 1 52  ? 150.207 155.347 193.200 1.00 51.95  ? 77  ARG A N   1 
ATOM   412   C CA  . ARG A 1 52  ? 149.329 155.405 194.362 1.00 51.95  ? 77  ARG A CA  1 
ATOM   413   C C   . ARG A 1 52  ? 147.869 155.310 193.923 1.00 51.95  ? 77  ARG A C   1 
ATOM   414   O O   . ARG A 1 52  ? 147.507 155.821 192.859 1.00 51.95  ? 77  ARG A O   1 
ATOM   415   C CB  . ARG A 1 52  ? 149.544 156.699 195.142 1.00 51.95  ? 77  ARG A CB  1 
ATOM   416   C CG  . ARG A 1 52  ? 149.444 157.958 194.297 1.00 51.95  ? 77  ARG A CG  1 
ATOM   417   C CD  . ARG A 1 52  ? 149.476 159.209 195.160 1.00 51.95  ? 77  ARG A CD  1 
ATOM   418   N NE  . ARG A 1 52  ? 150.670 159.270 195.997 1.00 51.95  ? 77  ARG A NE  1 
ATOM   419   C CZ  . ARG A 1 52  ? 150.935 160.255 196.849 1.00 51.95  ? 77  ARG A CZ  1 
ATOM   420   N NH1 . ARG A 1 52  ? 150.089 161.268 196.979 1.00 51.95  ? 77  ARG A NH1 1 
ATOM   421   N NH2 . ARG A 1 52  ? 152.048 160.230 197.570 1.00 51.95  ? 77  ARG A NH2 1 
ATOM   422   N N   . PRO A 1 53  ? 147.020 154.655 194.713 1.00 47.17  ? 78  PRO A N   1 
ATOM   423   C CA  . PRO A 1 53  ? 145.607 154.537 194.333 1.00 47.17  ? 78  PRO A CA  1 
ATOM   424   C C   . PRO A 1 53  ? 144.901 155.883 194.387 1.00 47.17  ? 78  PRO A C   1 
ATOM   425   O O   . PRO A 1 53  ? 145.143 156.698 195.280 1.00 47.17  ? 78  PRO A O   1 
ATOM   426   C CB  . PRO A 1 53  ? 145.035 153.564 195.372 1.00 47.17  ? 78  PRO A CB  1 
ATOM   427   C CG  . PRO A 1 53  ? 146.230 152.886 195.977 1.00 47.17  ? 78  PRO A CG  1 
ATOM   428   C CD  . PRO A 1 53  ? 147.328 153.897 195.936 1.00 47.17  ? 78  PRO A CD  1 
ATOM   429   N N   . GLY A 1 54  ? 144.020 156.108 193.416 1.00 51.91  ? 79  GLY A N   1 
ATOM   430   C CA  . GLY A 1 54  ? 143.244 157.329 193.366 1.00 51.91  ? 79  GLY A CA  1 
ATOM   431   C C   . GLY A 1 54  ? 143.885 158.476 192.621 1.00 51.91  ? 79  GLY A C   1 
ATOM   432   O O   . GLY A 1 54  ? 143.451 159.621 192.788 1.00 51.91  ? 79  GLY A O   1 
ATOM   433   N N   . ALA A 1 55  ? 144.903 158.211 191.804 1.00 48.73  ? 80  ALA A N   1 
ATOM   434   C CA  . ALA A 1 55  ? 145.586 159.251 191.046 1.00 48.73  ? 80  ALA A CA  1 
ATOM   435   C C   . ALA A 1 55  ? 145.092 159.364 189.611 1.00 48.73  ? 80  ALA A C   1 
ATOM   436   O O   . ALA A 1 55  ? 144.950 160.478 189.097 1.00 48.73  ? 80  ALA A O   1 
ATOM   437   C CB  . ALA A 1 55  ? 147.097 158.999 191.043 1.00 48.73  ? 80  ALA A CB  1 
ATOM   438   N N   . PHE A 1 56  ? 144.828 158.240 188.954 1.00 41.16  ? 81  PHE A N   1 
ATOM   439   C CA  . PHE A 1 56  ? 144.387 158.215 187.571 1.00 41.16  ? 81  PHE A CA  1 
ATOM   440   C C   . PHE A 1 56  ? 143.180 157.301 187.430 1.00 41.16  ? 81  PHE A C   1 
ATOM   441   O O   . PHE A 1 56  ? 143.007 156.370 188.224 1.00 41.16  ? 81  PHE A O   1 
ATOM   442   C CB  . PHE A 1 56  ? 145.513 157.734 186.643 1.00 41.16  ? 81  PHE A CB  1 
ATOM   443   C CG  . PHE A 1 56  ? 146.594 158.753 186.425 1.00 41.16  ? 81  PHE A CG  1 
ATOM   444   C CD1 . PHE A 1 56  ? 147.592 158.936 187.366 1.00 41.16  ? 81  PHE A CD1 1 
ATOM   445   C CD2 . PHE A 1 56  ? 146.612 159.528 185.278 1.00 41.16  ? 81  PHE A CD2 1 
ATOM   446   C CE1 . PHE A 1 56  ? 148.587 159.873 187.169 1.00 41.16  ? 81  PHE A CE1 1 
ATOM   447   C CE2 . PHE A 1 56  ? 147.605 160.467 185.075 1.00 41.16  ? 81  PHE A CE2 1 
ATOM   448   C CZ  . PHE A 1 56  ? 148.594 160.639 186.022 1.00 41.16  ? 81  PHE A CZ  1 
ATOM   449   N N   . PRO A 1 57  ? 142.323 157.549 186.440 1.00 26.48  ? 82  PRO A N   1 
ATOM   450   C CA  . PRO A 1 57  ? 141.152 156.687 186.247 1.00 26.48  ? 82  PRO A CA  1 
ATOM   451   C C   . PRO A 1 57  ? 141.556 155.249 185.957 1.00 26.48  ? 82  PRO A C   1 
ATOM   452   O O   . PRO A 1 57  ? 142.672 154.960 185.518 1.00 26.48  ? 82  PRO A O   1 
ATOM   453   C CB  . PRO A 1 57  ? 140.436 157.319 185.047 1.00 26.48  ? 82  PRO A CB  1 
ATOM   454   C CG  . PRO A 1 57  ? 140.902 158.736 185.034 1.00 26.48  ? 82  PRO A CG  1 
ATOM   455   C CD  . PRO A 1 57  ? 142.319 158.699 185.520 1.00 26.48  ? 82  PRO A CD  1 
ATOM   456   N N   . SER A 1 58  ? 140.622 154.339 186.206 1.00 40.44  ? 83  SER A N   1 
ATOM   457   C CA  . SER A 1 58  ? 140.891 152.914 186.106 1.00 40.44  ? 83  SER A CA  1 
ATOM   458   C C   . SER A 1 58  ? 140.508 152.374 184.732 1.00 40.44  ? 83  SER A C   1 
ATOM   459   O O   . SER A 1 58  ? 139.754 152.993 183.975 1.00 40.44  ? 83  SER A O   1 
ATOM   460   C CB  . SER A 1 58  ? 140.139 152.149 187.196 1.00 40.44  ? 83  SER A CB  1 
ATOM   461   O OG  . SER A 1 58  ? 140.837 152.200 188.428 1.00 40.44  ? 83  SER A OG  1 
ATOM   462   N N   . GLU A 1 59  ? 141.048 151.193 184.419 1.00 50.85  ? 84  GLU A N   1 
ATOM   463   C CA  . GLU A 1 59  ? 140.750 150.553 183.143 1.00 50.85  ? 84  GLU A CA  1 
ATOM   464   C C   . GLU A 1 59  ? 139.274 150.193 183.039 1.00 50.85  ? 84  GLU A C   1 
ATOM   465   O O   . GLU A 1 59  ? 138.676 150.304 181.964 1.00 50.85  ? 84  GLU A O   1 
ATOM   466   C CB  . GLU A 1 59  ? 141.619 149.308 182.966 1.00 50.85  ? 84  GLU A CB  1 
ATOM   467   C CG  . GLU A 1 59  ? 143.101 149.549 183.196 1.00 50.85  ? 84  GLU A CG  1 
ATOM   468   C CD  . GLU A 1 59  ? 143.916 148.274 183.124 1.00 50.85  ? 84  GLU A CD  1 
ATOM   469   O OE1 . GLU A 1 59  ? 143.336 147.214 182.808 1.00 50.85  ? 84  GLU A OE1 1 
ATOM   470   O OE2 . GLU A 1 59  ? 145.137 148.330 183.384 1.00 50.85  ? 84  GLU A OE2 1 
ATOM   471   N N   . GLU A 1 60  ? 138.669 149.762 184.148 1.00 49.93  ? 85  GLU A N   1 
ATOM   472   C CA  . GLU A 1 60  ? 137.244 149.450 184.133 1.00 49.93  ? 85  GLU A CA  1 
ATOM   473   C C   . GLU A 1 60  ? 136.414 150.693 183.839 1.00 49.93  ? 85  GLU A C   1 
ATOM   474   O O   . GLU A 1 60  ? 135.448 150.637 183.067 1.00 49.93  ? 85  GLU A O   1 
ATOM   475   C CB  . GLU A 1 60  ? 136.828 148.828 185.466 1.00 49.93  ? 85  GLU A CB  1 
ATOM   476   C CG  . GLU A 1 60  ? 135.349 148.489 185.565 1.00 49.93  ? 85  GLU A CG  1 
ATOM   477   C CD  . GLU A 1 60  ? 134.949 147.340 184.658 1.00 49.93  ? 85  GLU A CD  1 
ATOM   478   O OE1 . GLU A 1 60  ? 134.727 147.579 183.452 1.00 49.93  ? 85  GLU A OE1 1 
ATOM   479   O OE2 . GLU A 1 60  ? 134.858 146.197 185.152 1.00 49.93  ? 85  GLU A OE2 1 
ATOM   480   N N   . THR A 1 61  ? 136.781 151.829 184.436 1.00 36.80  ? 86  THR A N   1 
ATOM   481   C CA  . THR A 1 61  ? 136.069 153.072 184.163 1.00 36.80  ? 86  THR A CA  1 
ATOM   482   C C   . THR A 1 61  ? 136.252 153.505 182.713 1.00 36.80  ? 86  THR A C   1 
ATOM   483   O O   . THR A 1 61  ? 135.296 153.950 182.066 1.00 36.80  ? 86  THR A O   1 
ATOM   484   C CB  . THR A 1 61  ? 136.545 154.171 185.114 1.00 36.80  ? 86  THR A CB  1 
ATOM   485   O OG1 . THR A 1 61  ? 136.450 153.707 186.466 1.00 36.80  ? 86  THR A OG1 1 
ATOM   486   C CG2 . THR A 1 61  ? 135.693 155.421 184.953 1.00 36.80  ? 86  THR A CG2 1 
ATOM   487   N N   . LEU A 1 62  ? 137.474 153.383 182.186 1.00 35.65  ? 87  LEU A N   1 
ATOM   488   C CA  . LEU A 1 62  ? 137.716 153.753 180.795 1.00 35.65  ? 87  LEU A CA  1 
ATOM   489   C C   . LEU A 1 62  ? 136.956 152.850 179.833 1.00 35.65  ? 87  LEU A C   1 
ATOM   490   O O   . LEU A 1 62  ? 136.518 153.304 178.770 1.00 35.65  ? 87  LEU A O   1 
ATOM   491   C CB  . LEU A 1 62  ? 139.215 153.712 180.494 1.00 35.65  ? 87  LEU A CB  1 
ATOM   492   C CG  . LEU A 1 62  ? 139.938 155.061 180.465 1.00 35.65  ? 87  LEU A CG  1 
ATOM   493   C CD1 . LEU A 1 62  ? 139.779 155.787 181.788 1.00 35.65  ? 87  LEU A CD1 1 
ATOM   494   C CD2 . LEU A 1 62  ? 141.408 154.873 180.129 1.00 35.65  ? 87  LEU A CD2 1 
ATOM   495   N N   . ARG A 1 63  ? 136.786 151.573 180.185 1.00 37.18  ? 88  ARG A N   1 
ATOM   496   C CA  . ARG A 1 63  ? 136.019 150.669 179.336 1.00 37.18  ? 88  ARG A CA  1 
ATOM   497   C C   . ARG A 1 63  ? 134.528 150.969 179.419 1.00 37.18  ? 88  ARG A C   1 
ATOM   498   O O   . ARG A 1 63  ? 133.822 150.920 178.405 1.00 37.18  ? 88  ARG A O   1 
ATOM   499   C CB  . ARG A 1 63  ? 136.295 149.217 179.729 1.00 37.18  ? 88  ARG A CB  1 
ATOM   500   C CG  . ARG A 1 63  ? 137.293 148.500 178.832 1.00 37.18  ? 88  ARG A CG  1 
ATOM   501   C CD  . ARG A 1 63  ? 138.670 149.134 178.918 1.00 37.18  ? 88  ARG A CD  1 
ATOM   502   N NE  . ARG A 1 63  ? 139.677 148.363 178.195 1.00 37.18  ? 88  ARG A NE  1 
ATOM   503   C CZ  . ARG A 1 63  ? 140.452 147.439 178.753 1.00 37.18  ? 88  ARG A CZ  1 
ATOM   504   N NH1 . ARG A 1 63  ? 140.338 147.168 180.046 1.00 37.18  ? 88  ARG A NH1 1 
ATOM   505   N NH2 . ARG A 1 63  ? 141.342 146.786 178.019 1.00 37.18  ? 88  ARG A NH2 1 
ATOM   506   N N   . GLY A 1 64  ? 134.030 151.281 180.617 1.00 45.51  ? 89  GLY A N   1 
ATOM   507   C CA  . GLY A 1 64  ? 132.619 151.583 180.779 1.00 45.51  ? 89  GLY A CA  1 
ATOM   508   C C   . GLY A 1 64  ? 132.204 152.921 180.208 1.00 45.51  ? 89  GLY A C   1 
ATOM   509   O O   . GLY A 1 64  ? 131.035 153.090 179.843 1.00 45.51  ? 89  GLY A O   1 
ATOM   510   N N   . LEU A 1 65  ? 133.128 153.875 180.124 1.00 46.38  ? 90  LEU A N   1 
ATOM   511   C CA  . LEU A 1 65  ? 132.800 155.181 179.575 1.00 46.38  ? 90  LEU A CA  1 
ATOM   512   C C   . LEU A 1 65  ? 132.506 155.079 178.080 1.00 46.38  ? 90  LEU A C   1 
ATOM   513   O O   . LEU A 1 65  ? 132.932 154.145 177.394 1.00 46.38  ? 90  LEU A O   1 
ATOM   514   C CB  . LEU A 1 65  ? 133.943 156.166 179.826 1.00 46.38  ? 90  LEU A CB  1 
ATOM   515   C CG  . LEU A 1 65  ? 133.590 157.655 179.844 1.00 46.38  ? 90  LEU A CG  1 
ATOM   516   C CD1 . LEU A 1 65  ? 132.278 157.890 180.575 1.00 46.38  ? 90  LEU A CD1 1 
ATOM   517   C CD2 . LEU A 1 65  ? 134.710 158.458 180.484 1.00 46.38  ? 90  LEU A CD2 1 
ATOM   518   N N   . GLY A 1 66  ? 131.763 156.062 177.577 1.00 60.30  ? 91  GLY A N   1 
ATOM   519   C CA  . GLY A 1 66  ? 131.364 156.078 176.183 1.00 60.30  ? 91  GLY A CA  1 
ATOM   520   C C   . GLY A 1 66  ? 132.424 156.640 175.259 1.00 60.30  ? 91  GLY A C   1 
ATOM   521   O O   . GLY A 1 66  ? 133.589 156.236 175.322 1.00 60.30  ? 91  GLY A O   1 
ATOM   522   N N   . ARG A 1 67  ? 132.031 157.569 174.387 1.00 74.07  ? 92  ARG A N   1 
ATOM   523   C CA  . ARG A 1 67  ? 132.946 158.181 173.433 1.00 74.07  ? 92  ARG A CA  1 
ATOM   524   C C   . ARG A 1 67  ? 133.199 159.651 173.744 1.00 74.07  ? 92  ARG A C   1 
ATOM   525   O O   . ARG A 1 67  ? 134.352 160.059 173.914 1.00 74.07  ? 92  ARG A O   1 
ATOM   526   C CB  . ARG A 1 67  ? 132.398 158.019 172.008 1.00 74.07  ? 92  ARG A CB  1 
ATOM   527   C CG  . ARG A 1 67  ? 132.015 156.588 171.659 1.00 74.07  ? 92  ARG A CG  1 
ATOM   528   C CD  . ARG A 1 67  ? 131.527 156.471 170.224 1.00 74.07  ? 92  ARG A CD  1 
ATOM   529   N NE  . ARG A 1 67  ? 132.601 156.683 169.260 1.00 74.07  ? 92  ARG A NE  1 
ATOM   530   C CZ  . ARG A 1 67  ? 132.456 156.567 167.944 1.00 74.07  ? 92  ARG A CZ  1 
ATOM   531   N NH1 . ARG A 1 67  ? 133.489 156.777 167.139 1.00 74.07  ? 92  ARG A NH1 1 
ATOM   532   N NH2 . ARG A 1 67  ? 131.277 156.241 167.432 1.00 74.07  ? 92  ARG A NH2 1 
ATOM   533   N N   . ARG A 1 68  ? 132.144 160.464 173.838 1.00 54.35  ? 93  ARG A N   1 
ATOM   534   C CA  . ARG A 1 68  ? 132.338 161.881 174.131 1.00 54.35  ? 93  ARG A CA  1 
ATOM   535   C C   . ARG A 1 68  ? 132.834 162.087 175.559 1.00 54.35  ? 93  ARG A C   1 
ATOM   536   O O   . ARG A 1 68  ? 133.707 162.929 175.802 1.00 54.35  ? 93  ARG A O   1 
ATOM   537   C CB  . ARG A 1 68  ? 131.042 162.658 173.873 1.00 54.35  ? 93  ARG A CB  1 
ATOM   538   C CG  . ARG A 1 68  ? 129.923 162.439 174.886 1.00 54.35  ? 93  ARG A CG  1 
ATOM   539   C CD  . ARG A 1 68  ? 129.112 161.191 174.574 1.00 54.35  ? 93  ARG A CD  1 
ATOM   540   N NE  . ARG A 1 68  ? 127.911 161.098 175.398 1.00 54.35  ? 93  ARG A NE  1 
ATOM   541   C CZ  . ARG A 1 68  ? 127.154 160.011 175.495 1.00 54.35  ? 93  ARG A CZ  1 
ATOM   542   N NH1 . ARG A 1 68  ? 126.078 160.016 176.271 1.00 54.35  ? 93  ARG A NH1 1 
ATOM   543   N NH2 . ARG A 1 68  ? 127.473 158.916 174.819 1.00 54.35  ? 93  ARG A NH2 1 
ATOM   544   N N   . GLY A 1 69  ? 132.308 161.314 176.512 1.00 46.31  ? 94  GLY A N   1 
ATOM   545   C CA  . GLY A 1 69  ? 132.822 161.388 177.869 1.00 46.31  ? 94  GLY A CA  1 
ATOM   546   C C   . GLY A 1 69  ? 134.254 160.901 177.963 1.00 46.31  ? 94  GLY A C   1 
ATOM   547   O O   . GLY A 1 69  ? 135.061 161.458 178.712 1.00 46.31  ? 94  GLY A O   1 
ATOM   548   N N   . PHE A 1 70  ? 134.589 159.861 177.197 1.00 37.47  ? 95  PHE A N   1 
ATOM   549   C CA  . PHE A 1 70  ? 135.967 159.387 177.134 1.00 37.47  ? 95  PHE A CA  1 
ATOM   550   C C   . PHE A 1 70  ? 136.894 160.482 176.622 1.00 37.47  ? 95  PHE A C   1 
ATOM   551   O O   . PHE A 1 70  ? 137.967 160.724 177.189 1.00 37.47  ? 95  PHE A O   1 
ATOM   552   C CB  . PHE A 1 70  ? 136.040 158.148 176.239 1.00 37.47  ? 95  PHE A CB  1 
ATOM   553   C CG  . PHE A 1 70  ? 137.396 157.506 176.192 1.00 37.47  ? 95  PHE A CG  1 
ATOM   554   C CD1 . PHE A 1 70  ? 137.776 156.589 177.156 1.00 37.47  ? 95  PHE A CD1 1 
ATOM   555   C CD2 . PHE A 1 70  ? 138.284 157.806 175.174 1.00 37.47  ? 95  PHE A CD2 1 
ATOM   556   C CE1 . PHE A 1 70  ? 139.020 155.992 177.112 1.00 37.47  ? 95  PHE A CE1 1 
ATOM   557   C CE2 . PHE A 1 70  ? 139.530 157.213 175.125 1.00 37.47  ? 95  PHE A CE2 1 
ATOM   558   C CZ  . PHE A 1 70  ? 139.898 156.304 176.095 1.00 37.47  ? 95  PHE A CZ  1 
ATOM   559   N N   . LEU A 1 71  ? 136.485 161.164 175.550 1.00 40.48  ? 96  LEU A N   1 
ATOM   560   C CA  . LEU A 1 71  ? 137.309 162.230 174.990 1.00 40.48  ? 96  LEU A CA  1 
ATOM   561   C C   . LEU A 1 71  ? 137.455 163.390 175.967 1.00 40.48  ? 96  LEU A C   1 
ATOM   562   O O   . LEU A 1 71  ? 138.545 163.955 176.110 1.00 40.48  ? 96  LEU A O   1 
ATOM   563   C CB  . LEU A 1 71  ? 136.715 162.711 173.666 1.00 40.48  ? 96  LEU A CB  1 
ATOM   564   C CG  . LEU A 1 71  ? 136.798 161.733 172.492 1.00 40.48  ? 96  LEU A CG  1 
ATOM   565   C CD1 . LEU A 1 71  ? 136.122 162.312 171.260 1.00 40.48  ? 96  LEU A CD1 1 
ATOM   566   C CD2 . LEU A 1 71  ? 138.245 161.372 172.193 1.00 40.48  ? 96  LEU A CD2 1 
ATOM   567   N N   . GLN A 1 72  ? 136.371 163.757 176.656 1.00 37.00  ? 97  GLN A N   1 
ATOM   568   C CA  . GLN A 1 72  ? 136.447 164.853 177.619 1.00 37.00  ? 97  GLN A CA  1 
ATOM   569   C C   . GLN A 1 72  ? 137.350 164.499 178.796 1.00 37.00  ? 97  GLN A C   1 
ATOM   570   O O   . GLN A 1 72  ? 138.144 165.334 179.252 1.00 37.00  ? 97  GLN A O   1 
ATOM   571   C CB  . GLN A 1 72  ? 135.046 165.218 178.105 1.00 37.00  ? 97  GLN A CB  1 
ATOM   572   C CG  . GLN A 1 72  ? 134.178 165.875 177.045 1.00 37.00  ? 97  GLN A CG  1 
ATOM   573   C CD  . GLN A 1 72  ? 132.727 165.983 177.466 1.00 37.00  ? 97  GLN A CD  1 
ATOM   574   O OE1 . GLN A 1 72  ? 132.344 165.522 178.540 1.00 37.00  ? 97  GLN A OE1 1 
ATOM   575   N NE2 . GLN A 1 72  ? 131.909 166.596 176.617 1.00 37.00  ? 97  GLN A NE2 1 
ATOM   576   N N   . THR A 1 73  ? 137.240 163.268 179.303 1.00 34.43  ? 98  THR A N   1 
ATOM   577   C CA  . THR A 1 73  ? 138.107 162.836 180.393 1.00 34.43  ? 98  THR A CA  1 
ATOM   578   C C   . THR A 1 73  ? 139.565 162.820 179.959 1.00 34.43  ? 98  THR A C   1 
ATOM   579   O O   . THR A 1 73  ? 140.450 163.240 180.713 1.00 34.43  ? 98  THR A O   1 
ATOM   580   C CB  . THR A 1 73  ? 137.679 161.455 180.889 1.00 34.43  ? 98  THR A CB  1 
ATOM   581   O OG1 . THR A 1 73  ? 136.304 161.494 181.290 1.00 34.43  ? 98  THR A OG1 1 
ATOM   582   C CG2 . THR A 1 73  ? 138.533 161.023 182.071 1.00 34.43  ? 98  THR A CG2 1 
ATOM   583   N N   . LEU A 1 74  ? 139.836 162.346 178.739 1.00 36.27  ? 99  LEU A N   1 
ATOM   584   C CA  . LEU A 1 74  ? 141.206 162.342 178.239 1.00 36.27  ? 99  LEU A CA  1 
ATOM   585   C C   . LEU A 1 74  ? 141.735 163.762 178.073 1.00 36.27  ? 99  LEU A C   1 
ATOM   586   O O   . LEU A 1 74  ? 142.907 164.030 178.356 1.00 36.27  ? 99  LEU A O   1 
ATOM   587   C CB  . LEU A 1 74  ? 141.277 161.578 176.918 1.00 36.27  ? 99  LEU A CB  1 
ATOM   588   C CG  . LEU A 1 74  ? 142.670 161.242 176.382 1.00 36.27  ? 99  LEU A CG  1 
ATOM   589   C CD1 . LEU A 1 74  ? 143.602 160.833 177.509 1.00 36.27  ? 99  LEU A CD1 1 
ATOM   590   C CD2 . LEU A 1 74  ? 142.581 160.143 175.336 1.00 36.27  ? 99  LEU A CD2 1 
ATOM   591   N N   . ASN A 1 75  ? 140.879 164.686 177.635 1.00 45.23  ? 100 ASN A N   1 
ATOM   592   C CA  . ASN A 1 75  ? 141.277 166.084 177.496 1.00 45.23  ? 100 ASN A CA  1 
ATOM   593   C C   . ASN A 1 75  ? 141.641 166.688 178.849 1.00 45.23  ? 100 ASN A C   1 
ATOM   594   O O   . ASN A 1 75  ? 142.682 167.344 178.994 1.00 45.23  ? 100 ASN A O   1 
ATOM   595   C CB  . ASN A 1 75  ? 140.139 166.860 176.832 1.00 45.23  ? 100 ASN A CB  1 
ATOM   596   C CG  . ASN A 1 75  ? 140.484 168.310 176.557 1.00 45.23  ? 100 ASN A CG  1 
ATOM   597   O OD1 . ASN A 1 75  ? 141.649 168.707 176.557 1.00 45.23  ? 100 ASN A OD1 1 
ATOM   598   N ND2 . ASN A 1 75  ? 139.451 169.111 176.314 1.00 45.23  ? 100 ASN A ND2 1 
ATOM   599   N N   . ALA A 1 76  ? 140.791 166.470 179.856 1.00 34.26  ? 101 ALA A N   1 
ATOM   600   C CA  . ALA A 1 76  ? 141.075 166.998 181.189 1.00 34.26  ? 101 ALA A CA  1 
ATOM   601   C C   . ALA A 1 76  ? 142.340 166.379 181.772 1.00 34.26  ? 101 ALA A C   1 
ATOM   602   O O   . ALA A 1 76  ? 143.154 167.073 182.398 1.00 34.26  ? 101 ALA A O   1 
ATOM   603   C CB  . ALA A 1 76  ? 139.882 166.758 182.113 1.00 34.26  ? 101 ALA A CB  1 
ATOM   604   N N   . THR A 1 77  ? 142.525 165.071 181.573 1.00 41.27  ? 102 THR A N   1 
ATOM   605   C CA  . THR A 1 77  ? 143.725 164.413 182.074 1.00 41.27  ? 102 THR A CA  1 
ATOM   606   C C   . THR A 1 77  ? 144.971 164.953 181.389 1.00 41.27  ? 102 THR A C   1 
ATOM   607   O O   . THR A 1 77  ? 145.998 165.172 182.040 1.00 41.27  ? 102 THR A O   1 
ATOM   608   C CB  . THR A 1 77  ? 143.617 162.901 181.876 1.00 41.27  ? 102 THR A CB  1 
ATOM   609   O OG1 . THR A 1 77  ? 142.385 162.431 182.436 1.00 41.27  ? 102 THR A OG1 1 
ATOM   610   C CG2 . THR A 1 77  ? 144.777 162.191 182.557 1.00 41.27  ? 102 THR A CG2 1 
ATOM   611   N N   . LEU A 1 78  ? 144.902 165.176 180.074 1.00 82.10  ? 103 LEU A N   1 
ATOM   612   C CA  . LEU A 1 78  ? 146.041 165.740 179.361 1.00 82.10  ? 103 LEU A CA  1 
ATOM   613   C C   . LEU A 1 78  ? 146.358 167.143 179.856 1.00 82.10  ? 103 LEU A C   1 
ATOM   614   O O   . LEU A 1 78  ? 147.530 167.507 179.988 1.00 82.10  ? 103 LEU A O   1 
ATOM   615   C CB  . LEU A 1 78  ? 145.773 165.747 177.856 1.00 82.10  ? 103 LEU A CB  1 
ATOM   616   C CG  . LEU A 1 78  ? 145.896 164.402 177.137 1.00 82.10  ? 103 LEU A CG  1 
ATOM   617   C CD1 . LEU A 1 78  ? 145.869 164.599 175.630 1.00 82.10  ? 103 LEU A CD1 1 
ATOM   618   C CD2 . LEU A 1 78  ? 147.159 163.671 177.564 1.00 82.10  ? 103 LEU A CD2 1 
ATOM   619   N N   . GLY A 1 79  ? 145.329 167.942 180.145 1.00 66.31  ? 104 GLY A N   1 
ATOM   620   C CA  . GLY A 1 79  ? 145.575 169.257 180.719 1.00 66.31  ? 104 GLY A CA  1 
ATOM   621   C C   . GLY A 1 79  ? 146.266 169.186 182.069 1.00 66.31  ? 104 GLY A C   1 
ATOM   622   O O   . GLY A 1 79  ? 147.219 169.929 182.335 1.00 66.31  ? 104 GLY A O   1 
ATOM   623   N N   . CYS A 1 80  ? 145.797 168.289 182.941 1.00 82.10  ? 105 CYS A N   1 
ATOM   624   C CA  . CYS A 1 80  ? 146.414 168.151 184.258 1.00 82.10  ? 105 CYS A CA  1 
ATOM   625   C C   . CYS A 1 80  ? 147.862 167.684 184.147 1.00 82.10  ? 105 CYS A C   1 
ATOM   626   O O   . CYS A 1 80  ? 148.746 168.198 184.848 1.00 82.10  ? 105 CYS A O   1 
ATOM   627   C CB  . CYS A 1 80  ? 145.603 167.184 185.120 1.00 82.10  ? 105 CYS A CB  1 
ATOM   628   S SG  . CYS A 1 80  ? 146.292 166.902 186.766 1.00 82.10  ? 105 CYS A SG  1 
ATOM   629   N N   . VAL A 1 81  ? 148.124 166.708 183.274 1.00 74.91  ? 106 VAL A N   1 
ATOM   630   C CA  . VAL A 1 81  ? 149.490 166.229 183.094 1.00 74.91  ? 106 VAL A CA  1 
ATOM   631   C C   . VAL A 1 81  ? 150.364 167.308 182.471 1.00 74.91  ? 106 VAL A C   1 
ATOM   632   O O   . VAL A 1 81  ? 151.552 167.402 182.787 1.00 74.91  ? 106 VAL A O   1 
ATOM   633   C CB  . VAL A 1 81  ? 149.515 164.932 182.264 1.00 74.91  ? 106 VAL A CB  1 
ATOM   634   C CG1 . VAL A 1 81  ? 150.929 164.387 182.181 1.00 74.91  ? 106 VAL A CG1 1 
ATOM   635   C CG2 . VAL A 1 81  ? 148.616 163.889 182.898 1.00 74.91  ? 106 VAL A CG2 1 
ATOM   636   N N   . LEU A 1 82  ? 149.802 168.152 181.603 1.00 82.10  ? 107 LEU A N   1 
ATOM   637   C CA  . LEU A 1 82  ? 150.576 169.260 181.052 1.00 82.10  ? 107 LEU A CA  1 
ATOM   638   C C   . LEU A 1 82  ? 150.961 170.254 182.138 1.00 82.10  ? 107 LEU A C   1 
ATOM   639   O O   . LEU A 1 82  ? 152.100 170.735 182.173 1.00 82.10  ? 107 LEU A O   1 
ATOM   640   C CB  . LEU A 1 82  ? 149.785 169.955 179.944 1.00 82.10  ? 107 LEU A CB  1 
ATOM   641   C CG  . LEU A 1 82  ? 149.924 169.367 178.539 1.00 82.10  ? 107 LEU A CG  1 
ATOM   642   C CD1 . LEU A 1 82  ? 148.980 170.062 177.572 1.00 82.10  ? 107 LEU A CD1 1 
ATOM   643   C CD2 . LEU A 1 82  ? 151.363 169.470 178.058 1.00 82.10  ? 107 LEU A CD2 1 
ATOM   644   N N   . HIS A 1 83  ? 150.025 170.571 183.036 1.00 54.66  ? 108 HIS A N   1 
ATOM   645   C CA  . HIS A 1 83  ? 150.342 171.469 184.143 1.00 54.66  ? 108 HIS A CA  1 
ATOM   646   C C   . HIS A 1 83  ? 151.432 170.879 185.034 1.00 54.66  ? 108 HIS A C   1 
ATOM   647   O O   . HIS A 1 83  ? 152.408 171.558 185.386 1.00 54.66  ? 108 HIS A O   1 
ATOM   648   C CB  . HIS A 1 83  ? 149.081 171.766 184.955 1.00 54.66  ? 108 HIS A CB  1 
ATOM   649   C CG  . HIS A 1 83  ? 149.269 172.821 186.000 1.00 54.66  ? 108 HIS A CG  1 
ATOM   650   N ND1 . HIS A 1 83  ? 148.391 172.996 187.048 1.00 54.66  ? 108 HIS A ND1 1 
ATOM   651   C CD2 . HIS A 1 83  ? 150.234 173.758 186.157 1.00 54.66  ? 108 HIS A CD2 1 
ATOM   652   C CE1 . HIS A 1 83  ? 148.807 173.994 187.806 1.00 54.66  ? 108 HIS A CE1 1 
ATOM   653   N NE2 . HIS A 1 83  ? 149.923 174.474 187.288 1.00 54.66  ? 108 HIS A NE2 1 
ATOM   654   N N   . ARG A 1 84  ? 151.284 169.604 185.405 1.00 41.28  ? 109 ARG A N   1 
ATOM   655   C CA  . ARG A 1 84  ? 152.284 168.976 186.263 1.00 41.28  ? 109 ARG A CA  1 
ATOM   656   C C   . ARG A 1 84  ? 153.633 168.855 185.564 1.00 41.28  ? 109 ARG A C   1 
ATOM   657   O O   . ARG A 1 84  ? 154.679 168.970 186.213 1.00 41.28  ? 109 ARG A O   1 
ATOM   658   C CB  . ARG A 1 84  ? 151.798 167.603 186.725 1.00 41.28  ? 109 ARG A CB  1 
ATOM   659   C CG  . ARG A 1 84  ? 152.557 167.057 187.922 1.00 41.28  ? 109 ARG A CG  1 
ATOM   660   C CD  . ARG A 1 84  ? 151.655 166.225 188.817 1.00 41.28  ? 109 ARG A CD  1 
ATOM   661   N NE  . ARG A 1 84  ? 150.486 166.975 189.266 1.00 41.28  ? 109 ARG A NE  1 
ATOM   662   C CZ  . ARG A 1 84  ? 149.523 166.468 190.028 1.00 41.28  ? 109 ARG A CZ  1 
ATOM   663   N NH1 . ARG A 1 84  ? 149.586 165.206 190.429 1.00 41.28  ? 109 ARG A NH1 1 
ATOM   664   N NH2 . ARG A 1 84  ? 148.495 167.224 190.389 1.00 41.28  ? 109 ARG A NH2 1 
ATOM   665   N N   . LEU A 1 85  ? 153.634 168.647 184.246 1.00 54.57  ? 110 LEU A N   1 
ATOM   666   C CA  . LEU A 1 85  ? 154.889 168.555 183.511 1.00 54.57  ? 110 LEU A CA  1 
ATOM   667   C C   . LEU A 1 85  ? 155.564 169.914 183.410 1.00 54.57  ? 110 LEU A C   1 
ATOM   668   O O   . LEU A 1 85  ? 156.794 170.004 183.463 1.00 54.57  ? 110 LEU A O   1 
ATOM   669   C CB  . LEU A 1 85  ? 154.639 167.969 182.122 1.00 54.57  ? 110 LEU A CB  1 
ATOM   670   C CG  . LEU A 1 85  ? 155.876 167.744 181.254 1.00 54.57  ? 110 LEU A CG  1 
ATOM   671   C CD1 . LEU A 1 85  ? 156.930 166.973 182.028 1.00 54.57  ? 110 LEU A CD1 1 
ATOM   672   C CD2 . LEU A 1 85  ? 155.506 167.012 179.974 1.00 54.57  ? 110 LEU A CD2 1 
ATOM   673   N N   . ALA A 1 86  ? 154.778 170.983 183.267 1.00 82.10  ? 111 ALA A N   1 
ATOM   674   C CA  . ALA A 1 86  ? 155.352 172.323 183.326 1.00 82.10  ? 111 ALA A CA  1 
ATOM   675   C C   . ALA A 1 86  ? 155.974 172.585 184.691 1.00 82.10  ? 111 ALA A C   1 
ATOM   676   O O   . ALA A 1 86  ? 157.065 173.161 184.788 1.00 82.10  ? 111 ALA A O   1 
ATOM   677   C CB  . ALA A 1 86  ? 154.283 173.368 183.009 1.00 82.10  ? 111 ALA A CB  1 
ATOM   678   N N   . ASP A 1 87  ? 155.299 172.152 185.759 1.00 39.49  ? 112 ASP A N   1 
ATOM   679   C CA  . ASP A 1 87  ? 155.875 172.289 187.095 1.00 39.49  ? 112 ASP A CA  1 
ATOM   680   C C   . ASP A 1 87  ? 157.190 171.522 187.213 1.00 39.49  ? 112 ASP A C   1 
ATOM   681   O O   . ASP A 1 87  ? 158.182 172.046 187.736 1.00 39.49  ? 112 ASP A O   1 
ATOM   682   C CB  . ASP A 1 87  ? 154.878 171.808 188.149 1.00 39.49  ? 112 ASP A CB  1 
ATOM   683   C CG  . ASP A 1 87  ? 155.323 172.128 189.562 1.00 39.49  ? 112 ASP A CG  1 
ATOM   684   O OD1 . ASP A 1 87  ? 156.239 172.962 189.726 1.00 39.49  ? 112 ASP A OD1 1 
ATOM   685   O OD2 . ASP A 1 87  ? 154.759 171.544 190.511 1.00 39.49  ? 112 ASP A OD2 1 
ATOM   686   N N   . LEU A 1 88  ? 157.216 170.279 186.728 1.00 30.86  ? 113 LEU A N   1 
ATOM   687   C CA  . LEU A 1 88  ? 158.433 169.476 186.808 1.00 30.86  ? 113 LEU A CA  1 
ATOM   688   C C   . LEU A 1 88  ? 159.561 170.095 185.990 1.00 30.86  ? 113 LEU A C   1 
ATOM   689   O O   . LEU A 1 88  ? 160.724 170.078 186.412 1.00 30.86  ? 113 LEU A O   1 
ATOM   690   C CB  . LEU A 1 88  ? 158.153 168.047 186.343 1.00 30.86  ? 113 LEU A CB  1 
ATOM   691   C CG  . LEU A 1 88  ? 157.266 167.204 187.261 1.00 30.86  ? 113 LEU A CG  1 
ATOM   692   C CD1 . LEU A 1 88  ? 157.113 165.794 186.714 1.00 30.86  ? 113 LEU A CD1 1 
ATOM   693   C CD2 . LEU A 1 88  ? 157.828 167.178 188.673 1.00 30.86  ? 113 LEU A CD2 1 
ATOM   694   N N   . GLU A 1 89  ? 159.239 170.640 184.814 1.00 47.07  ? 114 GLU A N   1 
ATOM   695   C CA  . GLU A 1 89  ? 160.250 171.321 184.011 1.00 47.07  ? 114 GLU A CA  1 
ATOM   696   C C   . GLU A 1 89  ? 160.781 172.550 184.734 1.00 47.07  ? 114 GLU A C   1 
ATOM   697   O O   . GLU A 1 89  ? 161.973 172.869 184.640 1.00 47.07  ? 114 GLU A O   1 
ATOM   698   C CB  . GLU A 1 89  ? 159.672 171.704 182.649 1.00 47.07  ? 114 GLU A CB  1 
ATOM   699   C CG  . GLU A 1 89  ? 159.447 170.526 181.716 1.00 47.07  ? 114 GLU A CG  1 
ATOM   700   C CD  . GLU A 1 89  ? 158.712 170.918 180.450 1.00 47.07  ? 114 GLU A CD  1 
ATOM   701   O OE1 . GLU A 1 89  ? 159.201 171.814 179.730 1.00 47.07  ? 114 GLU A OE1 1 
ATOM   702   O OE2 . GLU A 1 89  ? 157.645 170.330 180.175 1.00 47.07  ? 114 GLU A OE2 1 
ATOM   703   N N   . GLN A 1 90  ? 159.910 173.256 185.457 1.00 38.40  ? 115 GLN A N   1 
ATOM   704   C CA  . GLN A 1 90  ? 160.376 174.346 186.305 1.00 38.40  ? 115 GLN A CA  1 
ATOM   705   C C   . GLN A 1 90  ? 161.272 173.832 187.426 1.00 38.40  ? 115 GLN A C   1 
ATOM   706   O O   . GLN A 1 90  ? 162.161 174.555 187.890 1.00 38.40  ? 115 GLN A O   1 
ATOM   707   C CB  . GLN A 1 90  ? 159.181 175.106 186.882 1.00 38.40  ? 115 GLN A CB  1 
ATOM   708   C CG  . GLN A 1 90  ? 159.550 176.320 187.719 1.00 38.40  ? 115 GLN A CG  1 
ATOM   709   C CD  . GLN A 1 90  ? 158.343 176.974 188.359 1.00 38.40  ? 115 GLN A CD  1 
ATOM   710   O OE1 . GLN A 1 90  ? 158.460 177.999 189.030 1.00 38.40  ? 115 GLN A OE1 1 
ATOM   711   N NE2 . GLN A 1 90  ? 157.172 176.381 188.156 1.00 38.40  ? 115 GLN A NE2 1 
ATOM   712   N N   . ARG A 1 91  ? 161.064 172.588 187.861 1.00 26.36  ? 116 ARG A N   1 
ATOM   713   C CA  . ARG A 1 91  ? 161.835 172.050 188.976 1.00 26.36  ? 116 ARG A CA  1 
ATOM   714   C C   . ARG A 1 91  ? 163.196 171.506 188.552 1.00 26.36  ? 116 ARG A C   1 
ATOM   715   O O   . ARG A 1 91  ? 164.161 171.613 189.317 1.00 26.36  ? 116 ARG A O   1 
ATOM   716   C CB  . ARG A 1 91  ? 161.039 170.952 189.682 1.00 26.36  ? 116 ARG A CB  1 
ATOM   717   C CG  . ARG A 1 91  ? 160.088 171.467 190.747 1.00 26.36  ? 116 ARG A CG  1 
ATOM   718   C CD  . ARG A 1 91  ? 160.850 172.092 191.903 1.00 26.36  ? 116 ARG A CD  1 
ATOM   719   N NE  . ARG A 1 91  ? 159.953 172.605 192.933 1.00 26.36  ? 116 ARG A NE  1 
ATOM   720   C CZ  . ARG A 1 91  ? 159.465 173.841 192.948 1.00 26.36  ? 116 ARG A CZ  1 
ATOM   721   N NH1 . ARG A 1 91  ? 159.786 174.694 191.985 1.00 26.36  ? 116 ARG A NH1 1 
ATOM   722   N NH2 . ARG A 1 91  ? 158.654 174.224 193.924 1.00 26.36  ? 116 ARG A NH2 1 
ATOM   723   N N   . LEU A 1 92  ? 163.300 170.924 187.359 1.00 26.39  ? 117 LEU A N   1 
ATOM   724   C CA  . LEU A 1 92  ? 164.526 170.241 186.972 1.00 26.39  ? 117 LEU A CA  1 
ATOM   725   C C   . LEU A 1 92  ? 165.661 171.236 186.720 1.00 26.39  ? 117 LEU A C   1 
ATOM   726   O O   . LEU A 1 92  ? 165.420 172.383 186.333 1.00 26.39  ? 117 LEU A O   1 
ATOM   727   C CB  . LEU A 1 92  ? 164.291 169.379 185.731 1.00 26.39  ? 117 LEU A CB  1 
ATOM   728   C CG  . LEU A 1 92  ? 163.642 169.978 184.481 1.00 26.39  ? 117 LEU A CG  1 
ATOM   729   C CD1 . LEU A 1 92  ? 164.654 170.670 183.582 1.00 26.39  ? 117 LEU A CD1 1 
ATOM   730   C CD2 . LEU A 1 92  ? 162.911 168.886 183.713 1.00 26.39  ? 117 LEU A CD2 1 
ATOM   731   N N   . PRO A 1 93  ? 166.917 170.816 186.938 1.00 31.19  ? 118 PRO A N   1 
ATOM   732   C CA  . PRO A 1 93  ? 168.054 171.730 186.750 1.00 31.19  ? 118 PRO A CA  1 
ATOM   733   C C   . PRO A 1 93  ? 168.377 171.996 185.288 1.00 31.19  ? 118 PRO A C   1 
ATOM   734   O O   . PRO A 1 93  ? 167.651 171.558 184.390 1.00 31.19  ? 118 PRO A O   1 
ATOM   735   C CB  . PRO A 1 93  ? 169.213 171.001 187.448 1.00 31.19  ? 118 PRO A CB  1 
ATOM   736   C CG  . PRO A 1 93  ? 168.575 169.908 188.261 1.00 31.19  ? 118 PRO A CG  1 
ATOM   737   C CD  . PRO A 1 93  ? 167.339 169.532 187.519 1.00 31.19  ? 118 PRO A CD  1 
ATOM   738   N N   . LYS A 1 94  ? 169.470 172.713 185.043 1.00 64.18  ? 119 LYS A N   1 
ATOM   739   C CA  . LYS A 1 94  ? 169.861 173.104 183.698 1.00 64.18  ? 119 LYS A CA  1 
ATOM   740   C C   . LYS A 1 94  ? 170.816 172.084 183.082 1.00 64.18  ? 119 LYS A C   1 
ATOM   741   O O   . LYS A 1 94  ? 171.454 171.288 183.777 1.00 64.18  ? 119 LYS A O   1 
ATOM   742   C CB  . LYS A 1 94  ? 170.511 174.488 183.710 1.00 64.18  ? 119 LYS A CB  1 
ATOM   743   C CG  . LYS A 1 94  ? 169.622 175.592 183.161 1.00 64.18  ? 119 LYS A CG  1 
ATOM   744   C CD  . LYS A 1 94  ? 168.275 175.617 183.865 1.00 64.18  ? 119 LYS A CD  1 
ATOM   745   C CE  . LYS A 1 94  ? 167.350 176.656 183.253 1.00 64.18  ? 119 LYS A CE  1 
ATOM   746   N NZ  . LYS A 1 94  ? 166.002 176.639 183.885 1.00 64.18  ? 119 LYS A NZ  1 
ATOM   747   N N   . ALA A 1 95  ? 170.915 172.134 181.751 1.00 66.38  ? 120 ALA A N   1 
ATOM   748   C CA  . ALA A 1 95  ? 171.710 171.151 181.020 1.00 66.38  ? 120 ALA A CA  1 
ATOM   749   C C   . ALA A 1 95  ? 173.196 171.288 181.330 1.00 66.38  ? 120 ALA A C   1 
ATOM   750   O O   . ALA A 1 95  ? 173.913 170.283 181.407 1.00 66.38  ? 120 ALA A O   1 
ATOM   751   C CB  . ALA A 1 95  ? 171.461 171.287 179.519 1.00 66.38  ? 120 ALA A CB  1 
ATOM   752   N N   . GLN A 1 96  ? 173.680 172.520 181.503 1.00 72.36  ? 121 GLN A N   1 
ATOM   753   C CA  . GLN A 1 96  ? 175.086 172.706 181.844 1.00 72.36  ? 121 GLN A CA  1 
ATOM   754   C C   . GLN A 1 96  ? 175.401 172.117 183.214 1.00 72.36  ? 121 GLN A C   1 
ATOM   755   O O   . GLN A 1 96  ? 176.446 171.482 183.398 1.00 72.36  ? 121 GLN A O   1 
ATOM   756   C CB  . GLN A 1 96  ? 175.455 174.191 181.789 1.00 72.36  ? 121 GLN A CB  1 
ATOM   757   C CG  . GLN A 1 96  ? 174.572 175.103 182.627 1.00 72.36  ? 121 GLN A CG  1 
ATOM   758   C CD  . GLN A 1 96  ? 173.382 175.637 181.854 1.00 72.36  ? 121 GLN A CD  1 
ATOM   759   O OE1 . GLN A 1 96  ? 173.034 175.119 180.793 1.00 72.36  ? 121 GLN A OE1 1 
ATOM   760   N NE2 . GLN A 1 96  ? 172.754 176.681 182.381 1.00 72.36  ? 121 GLN A NE2 1 
ATOM   761   N N   . ASP A 1 97  ? 174.497 172.294 184.181 1.00 81.03  ? 122 ASP A N   1 
ATOM   762   C CA  . ASP A 1 97  ? 174.703 171.699 185.496 1.00 81.03  ? 122 ASP A CA  1 
ATOM   763   C C   . ASP A 1 97  ? 174.626 170.179 185.429 1.00 81.03  ? 122 ASP A C   1 
ATOM   764   O O   . ASP A 1 97  ? 175.375 169.483 186.124 1.00 81.03  ? 122 ASP A O   1 
ATOM   765   C CB  . ASP A 1 97  ? 173.681 172.249 186.490 1.00 81.03  ? 122 ASP A CB  1 
ATOM   766   C CG  . ASP A 1 97  ? 174.111 172.064 187.932 1.00 81.03  ? 122 ASP A CG  1 
ATOM   767   O OD1 . ASP A 1 97  ? 174.252 170.903 188.371 1.00 81.03  ? 122 ASP A OD1 1 
ATOM   768   O OD2 . ASP A 1 97  ? 174.316 173.081 188.626 1.00 81.03  ? 122 ASP A OD2 1 
ATOM   769   N N   . LEU A 1 98  ? 173.729 169.646 184.596 1.00 83.59  ? 123 LEU A N   1 
ATOM   770   C CA  . LEU A 1 98  ? 173.659 168.199 184.412 1.00 83.59  ? 123 LEU A CA  1 
ATOM   771   C C   . LEU A 1 98  ? 174.968 167.656 183.854 1.00 83.59  ? 123 LEU A C   1 
ATOM   772   O O   . LEU A 1 98  ? 175.497 166.648 184.339 1.00 83.59  ? 123 LEU A O   1 
ATOM   773   C CB  . LEU A 1 98  ? 172.493 167.842 183.489 1.00 83.59  ? 123 LEU A CB  1 
ATOM   774   C CG  . LEU A 1 98  ? 171.084 168.157 183.994 1.00 83.59  ? 123 LEU A CG  1 
ATOM   775   C CD1 . LEU A 1 98  ? 170.066 167.964 182.882 1.00 83.59  ? 123 LEU A CD1 1 
ATOM   776   C CD2 . LEU A 1 98  ? 170.738 167.303 185.202 1.00 83.59  ? 123 LEU A CD2 1 
ATOM   777   N N   . GLU A 1 99  ? 175.509 168.320 182.829 1.00 100.77 ? 124 GLU A N   1 
ATOM   778   C CA  . GLU A 1 99  ? 176.758 167.867 182.226 1.00 100.77 ? 124 GLU A CA  1 
ATOM   779   C C   . GLU A 1 99  ? 177.925 168.009 183.197 1.00 100.77 ? 124 GLU A C   1 
ATOM   780   O O   . GLU A 1 99  ? 178.842 167.179 183.197 1.00 100.77 ? 124 GLU A O   1 
ATOM   781   C CB  . GLU A 1 99  ? 177.030 168.644 180.938 1.00 100.77 ? 124 GLU A CB  1 
ATOM   782   C CG  . GLU A 1 99  ? 178.071 168.004 180.032 1.00 100.77 ? 124 GLU A CG  1 
ATOM   783   C CD  . GLU A 1 99  ? 179.480 168.475 180.335 1.00 100.77 ? 124 GLU A CD  1 
ATOM   784   O OE1 . GLU A 1 99  ? 179.628 169.526 180.993 1.00 100.77 ? 124 GLU A OE1 1 
ATOM   785   O OE2 . GLU A 1 99  ? 180.440 167.794 179.915 1.00 100.77 ? 124 GLU A OE2 1 
ATOM   786   N N   . ARG A 1 100 ? 177.911 169.053 184.028 1.00 104.68 ? 125 ARG A N   1 
ATOM   787   C CA  . ARG A 1 100 ? 178.971 169.221 185.017 1.00 104.68 ? 125 ARG A CA  1 
ATOM   788   C C   . ARG A 1 100 ? 178.906 168.136 186.086 1.00 104.68 ? 125 ARG A C   1 
ATOM   789   O O   . ARG A 1 100 ? 179.939 167.589 186.487 1.00 104.68 ? 125 ARG A O   1 
ATOM   790   C CB  . ARG A 1 100 ? 178.883 170.611 185.648 1.00 104.68 ? 125 ARG A CB  1 
ATOM   791   C CG  . ARG A 1 100 ? 179.685 170.769 186.930 1.00 104.68 ? 125 ARG A CG  1 
ATOM   792   C CD  . ARG A 1 100 ? 178.775 170.929 188.137 1.00 104.68 ? 125 ARG A CD  1 
ATOM   793   N NE  . ARG A 1 100 ? 179.524 170.930 189.390 1.00 104.68 ? 125 ARG A NE  1 
ATOM   794   C CZ  . ARG A 1 100 ? 178.971 171.060 190.591 1.00 104.68 ? 125 ARG A CZ  1 
ATOM   795   N NH1 . ARG A 1 100 ? 177.658 171.200 190.708 1.00 104.68 ? 125 ARG A NH1 1 
ATOM   796   N NH2 . ARG A 1 100 ? 179.731 171.049 191.677 1.00 104.68 ? 125 ARG A NH2 1 
ATOM   797   N N   . SER A 1 101 ? 177.699 167.810 186.557 1.00 98.25  ? 126 SER A N   1 
ATOM   798   C CA  . SER A 1 101 ? 177.558 166.777 187.578 1.00 98.25  ? 126 SER A CA  1 
ATOM   799   C C   . SER A 1 101 ? 177.855 165.391 187.022 1.00 98.25  ? 126 SER A C   1 
ATOM   800   O O   . SER A 1 101 ? 178.342 164.523 187.756 1.00 98.25  ? 126 SER A O   1 
ATOM   801   C CB  . SER A 1 101 ? 176.152 166.819 188.176 1.00 98.25  ? 126 SER A CB  1 
ATOM   802   O OG  . SER A 1 101 ? 175.171 166.955 187.164 1.00 98.25  ? 126 SER A OG  1 
ATOM   803   N N   . GLY A 1 102 ? 177.573 165.161 185.742 1.00 89.52  ? 127 GLY A N   1 
ATOM   804   C CA  . GLY A 1 102 ? 177.875 163.882 185.130 1.00 89.52  ? 127 GLY A CA  1 
ATOM   805   C C   . GLY A 1 102 ? 176.657 163.163 184.591 1.00 89.52  ? 127 GLY A C   1 
ATOM   806   O O   . GLY A 1 102 ? 176.752 162.013 184.151 1.00 89.52  ? 127 GLY A O   1 
ATOM   807   N N   . LEU A 1 103 ? 175.506 163.827 184.619 1.00 68.64  ? 128 LEU A N   1 
ATOM   808   C CA  . LEU A 1 103 ? 174.277 163.248 184.092 1.00 68.64  ? 128 LEU A CA  1 
ATOM   809   C C   . LEU A 1 103 ? 174.228 163.462 182.580 1.00 68.64  ? 128 LEU A C   1 
ATOM   810   O O   . LEU A 1 103 ? 175.175 163.960 181.966 1.00 68.64  ? 128 LEU A O   1 
ATOM   811   C CB  . LEU A 1 103 ? 173.066 163.843 184.805 1.00 68.64  ? 128 LEU A CB  1 
ATOM   812   C CG  . LEU A 1 103 ? 173.006 163.605 186.316 1.00 68.64  ? 128 LEU A CG  1 
ATOM   813   C CD1 . LEU A 1 103 ? 171.732 164.188 186.906 1.00 68.64  ? 128 LEU A CD1 1 
ATOM   814   C CD2 . LEU A 1 103 ? 173.117 162.121 186.631 1.00 68.64  ? 128 LEU A CD2 1 
ATOM   815   N N   . ASN A 1 104 ? 173.115 163.084 181.958 1.00 54.46  ? 129 ASN A N   1 
ATOM   816   C CA  . ASN A 1 104 ? 172.951 163.174 180.515 1.00 54.46  ? 129 ASN A CA  1 
ATOM   817   C C   . ASN A 1 104 ? 171.754 164.053 180.181 1.00 54.46  ? 129 ASN A C   1 
ATOM   818   O O   . ASN A 1 104 ? 170.742 164.037 180.889 1.00 54.46  ? 129 ASN A O   1 
ATOM   819   C CB  . ASN A 1 104 ? 172.771 161.785 179.893 1.00 54.46  ? 129 ASN A CB  1 
ATOM   820   C CG  . ASN A 1 104 ? 172.915 161.799 178.385 1.00 54.46  ? 129 ASN A CG  1 
ATOM   821   O OD1 . ASN A 1 104 ? 173.339 162.796 177.799 1.00 54.46  ? 129 ASN A OD1 1 
ATOM   822   N ND2 . ASN A 1 104 ? 172.563 160.689 177.747 1.00 54.46  ? 129 ASN A ND2 1 
ATOM   823   N N   . ILE A 1 105 ? 171.877 164.822 179.093 1.00 38.14  ? 130 ILE A N   1 
ATOM   824   C CA  . ILE A 1 105 ? 170.789 165.687 178.641 1.00 38.14  ? 130 ILE A CA  1 
ATOM   825   C C   . ILE A 1 105 ? 169.748 164.942 177.825 1.00 38.14  ? 130 ILE A C   1 
ATOM   826   O O   . ILE A 1 105 ? 168.760 165.553 177.392 1.00 38.14  ? 130 ILE A O   1 
ATOM   827   C CB  . ILE A 1 105 ? 171.336 166.864 177.810 1.00 38.14  ? 130 ILE A CB  1 
ATOM   828   C CG1 . ILE A 1 105 ? 172.068 166.345 176.571 1.00 38.14  ? 130 ILE A CG1 1 
ATOM   829   C CG2 . ILE A 1 105 ? 172.260 167.726 178.654 1.00 38.14  ? 130 ILE A CG2 1 
ATOM   830   C CD1 . ILE A 1 105 ? 172.636 167.440 175.694 1.00 38.14  ? 130 ILE A CD1 1 
ATOM   831   N N   . GLU A 1 106 ? 169.942 163.641 177.596 1.00 40.87  ? 131 GLU A N   1 
ATOM   832   C CA  . GLU A 1 106 ? 168.954 162.862 176.859 1.00 40.87  ? 131 GLU A CA  1 
ATOM   833   C C   . GLU A 1 106 ? 167.623 162.813 177.594 1.00 40.87  ? 131 GLU A C   1 
ATOM   834   O O   . GLU A 1 106 ? 166.567 162.770 176.958 1.00 40.87  ? 131 GLU A O   1 
ATOM   835   C CB  . GLU A 1 106 ? 169.480 161.447 176.613 1.00 40.87  ? 131 GLU A CB  1 
ATOM   836   C CG  . GLU A 1 106 ? 168.725 160.681 175.539 1.00 40.87  ? 131 GLU A CG  1 
ATOM   837   C CD  . GLU A 1 106 ? 169.053 161.160 174.139 1.00 40.87  ? 131 GLU A CD  1 
ATOM   838   O OE1 . GLU A 1 106 ? 170.100 161.819 173.963 1.00 40.87  ? 131 GLU A OE1 1 
ATOM   839   O OE2 . GLU A 1 106 ? 168.264 160.876 173.213 1.00 40.87  ? 131 GLU A OE2 1 
ATOM   840   N N   . ASP A 1 107 ? 167.652 162.837 178.928 1.00 35.51  ? 132 ASP A N   1 
ATOM   841   C CA  . ASP A 1 107 ? 166.413 162.834 179.698 1.00 35.51  ? 132 ASP A CA  1 
ATOM   842   C C   . ASP A 1 107 ? 165.624 164.118 179.467 1.00 35.51  ? 132 ASP A C   1 
ATOM   843   O O   . ASP A 1 107 ? 164.409 164.085 179.224 1.00 35.51  ? 132 ASP A O   1 
ATOM   844   C CB  . ASP A 1 107 ? 166.732 162.651 181.182 1.00 35.51  ? 132 ASP A CB  1 
ATOM   845   C CG  . ASP A 1 107 ? 167.600 161.433 181.442 1.00 35.51  ? 132 ASP A CG  1 
ATOM   846   O OD1 . ASP A 1 107 ? 167.591 160.505 180.606 1.00 35.51  ? 132 ASP A OD1 1 
ATOM   847   O OD2 . ASP A 1 107 ? 168.294 161.406 182.479 1.00 35.51  ? 132 ASP A OD2 1 
ATOM   848   N N   . LEU A 1 108 ? 166.304 165.264 179.542 1.00 29.43  ? 133 LEU A N   1 
ATOM   849   C CA  . LEU A 1 108 ? 165.645 166.536 179.270 1.00 29.43  ? 133 LEU A CA  1 
ATOM   850   C C   . LEU A 1 108 ? 165.141 166.596 177.834 1.00 29.43  ? 133 LEU A C   1 
ATOM   851   O O   . LEU A 1 108 ? 164.057 167.129 177.571 1.00 29.43  ? 133 LEU A O   1 
ATOM   852   C CB  . LEU A 1 108 ? 166.605 167.692 179.553 1.00 29.43  ? 133 LEU A CB  1 
ATOM   853   C CG  . LEU A 1 108 ? 166.076 169.097 179.271 1.00 29.43  ? 133 LEU A CG  1 
ATOM   854   C CD1 . LEU A 1 108 ? 164.828 169.373 180.093 1.00 29.43  ? 133 LEU A CD1 1 
ATOM   855   C CD2 . LEU A 1 108 ? 167.149 170.136 179.552 1.00 29.43  ? 133 LEU A CD2 1 
ATOM   856   N N   . GLU A 1 109 ? 165.915 166.051 176.891 1.00 48.66  ? 134 GLU A N   1 
ATOM   857   C CA  . GLU A 1 109 ? 165.466 166.013 175.503 1.00 48.66  ? 134 GLU A CA  1 
ATOM   858   C C   . GLU A 1 109 ? 164.207 165.167 175.356 1.00 48.66  ? 134 GLU A C   1 
ATOM   859   O O   . GLU A 1 109 ? 163.270 165.551 174.647 1.00 48.66  ? 134 GLU A O   1 
ATOM   860   C CB  . GLU A 1 109 ? 166.582 165.480 174.605 1.00 48.66  ? 134 GLU A CB  1 
ATOM   861   C CG  . GLU A 1 109 ? 166.243 165.474 173.122 1.00 48.66  ? 134 GLU A CG  1 
ATOM   862   C CD  . GLU A 1 109 ? 165.702 164.138 172.650 1.00 48.66  ? 134 GLU A CD  1 
ATOM   863   O OE1 . GLU A 1 109 ? 165.776 163.158 173.421 1.00 48.66  ? 134 GLU A OE1 1 
ATOM   864   O OE2 . GLU A 1 109 ? 165.203 164.067 171.507 1.00 48.66  ? 134 GLU A OE2 1 
ATOM   865   N N   . LYS A 1 110 ? 164.162 164.017 176.031 1.00 36.63  ? 135 LYS A N   1 
ATOM   866   C CA  . LYS A 1 110 ? 162.989 163.155 175.949 1.00 36.63  ? 135 LYS A CA  1 
ATOM   867   C C   . LYS A 1 110 ? 161.765 163.827 176.556 1.00 36.63  ? 135 LYS A C   1 
ATOM   868   O O   . LYS A 1 110 ? 160.659 163.704 176.023 1.00 36.63  ? 135 LYS A O   1 
ATOM   869   C CB  . LYS A 1 110 ? 163.271 161.818 176.635 1.00 36.63  ? 135 LYS A CB  1 
ATOM   870   C CG  . LYS A 1 110 ? 164.176 160.898 175.832 1.00 36.63  ? 135 LYS A CG  1 
ATOM   871   C CD  . LYS A 1 110 ? 164.371 159.560 176.525 1.00 36.63  ? 135 LYS A CD  1 
ATOM   872   C CE  . LYS A 1 110 ? 165.256 158.640 175.700 1.00 36.63  ? 135 LYS A CE  1 
ATOM   873   N NZ  . LYS A 1 110 ? 165.427 157.308 176.343 1.00 36.63  ? 135 LYS A NZ  1 
ATOM   874   N N   . LEU A 1 111 ? 161.942 164.557 177.659 1.00 30.73  ? 136 LEU A N   1 
ATOM   875   C CA  . LEU A 1 111 ? 160.802 165.258 178.251 1.00 30.73  ? 136 LEU A CA  1 
ATOM   876   C C   . LEU A 1 111 ? 160.320 166.397 177.355 1.00 30.73  ? 136 LEU A C   1 
ATOM   877   O O   . LEU A 1 111 ? 159.107 166.570 177.150 1.00 30.73  ? 136 LEU A O   1 
ATOM   878   C CB  . LEU A 1 111 ? 161.163 165.777 179.642 1.00 30.73  ? 136 LEU A CB  1 
ATOM   879   C CG  . LEU A 1 111 ? 160.917 164.834 180.827 1.00 30.73  ? 136 LEU A CG  1 
ATOM   880   C CD1 . LEU A 1 111 ? 159.431 164.556 180.979 1.00 30.73  ? 136 LEU A CD1 1 
ATOM   881   C CD2 . LEU A 1 111 ? 161.687 163.529 180.699 1.00 30.73  ? 136 LEU A CD2 1 
ATOM   882   N N   . GLN A 1 112 ? 161.253 167.190 176.819 1.00 46.60  ? 137 GLN A N   1 
ATOM   883   C CA  . GLN A 1 112 ? 160.903 168.291 175.932 1.00 46.60  ? 137 GLN A CA  1 
ATOM   884   C C   . GLN A 1 112 ? 160.414 167.819 174.572 1.00 46.60  ? 137 GLN A C   1 
ATOM   885   O O   . GLN A 1 112 ? 159.925 168.641 173.791 1.00 46.60  ? 137 GLN A O   1 
ATOM   886   C CB  . GLN A 1 112 ? 162.105 169.221 175.759 1.00 46.60  ? 137 GLN A CB  1 
ATOM   887   C CG  . GLN A 1 112 ? 162.498 169.964 177.025 1.00 46.60  ? 137 GLN A CG  1 
ATOM   888   C CD  . GLN A 1 112 ? 163.799 170.725 176.874 1.00 46.60  ? 137 GLN A CD  1 
ATOM   889   O OE1 . GLN A 1 112 ? 164.579 170.469 175.957 1.00 46.60  ? 137 GLN A OE1 1 
ATOM   890   N NE2 . GLN A 1 112 ? 164.041 171.669 177.776 1.00 46.60  ? 137 GLN A NE2 1 
ATOM   891   N N   . MET A 1 113 ? 160.569 166.534 174.257 1.00 72.38  ? 138 MET A N   1 
ATOM   892   C CA  . MET A 1 113 ? 159.931 165.955 173.083 1.00 72.38  ? 138 MET A CA  1 
ATOM   893   C C   . MET A 1 113 ? 158.581 165.332 173.412 1.00 72.38  ? 138 MET A C   1 
ATOM   894   O O   . MET A 1 113 ? 157.683 165.325 172.562 1.00 72.38  ? 138 MET A O   1 
ATOM   895   C CB  . MET A 1 113 ? 160.846 164.899 172.454 1.00 72.38  ? 138 MET A CB  1 
ATOM   896   C CG  . MET A 1 113 ? 160.379 164.369 171.106 1.00 72.38  ? 138 MET A CG  1 
ATOM   897   S SD  . MET A 1 113 ? 159.943 165.677 169.946 1.00 72.38  ? 138 MET A SD  1 
ATOM   898   C CE  . MET A 1 113 ? 158.308 165.155 169.435 1.00 72.38  ? 138 MET A CE  1 
ATOM   899   N N   . ALA A 1 114 ? 158.418 164.818 174.633 1.00 82.10  ? 139 ALA A N   1 
ATOM   900   C CA  . ALA A 1 114 ? 157.160 164.202 175.033 1.00 82.10  ? 139 ALA A CA  1 
ATOM   901   C C   . ALA A 1 114 ? 156.079 165.233 175.320 1.00 82.10  ? 139 ALA A C   1 
ATOM   902   O O   . ALA A 1 114 ? 154.892 164.937 175.148 1.00 82.10  ? 139 ALA A O   1 
ATOM   903   C CB  . ALA A 1 114 ? 157.376 163.316 176.260 1.00 82.10  ? 139 ALA A CB  1 
ATOM   904   N N   . ARG A 1 115 ? 156.455 166.431 175.769 1.00 39.07  ? 140 ARG A N   1 
ATOM   905   C CA  . ARG A 1 115 ? 155.446 167.472 175.965 1.00 39.07  ? 140 ARG A CA  1 
ATOM   906   C C   . ARG A 1 115 ? 154.746 167.858 174.662 1.00 39.07  ? 140 ARG A C   1 
ATOM   907   O O   . ARG A 1 115 ? 153.499 167.879 174.636 1.00 39.07  ? 140 ARG A O   1 
ATOM   908   C CB  . ARG A 1 115 ? 156.077 168.686 176.657 1.00 39.07  ? 140 ARG A CB  1 
ATOM   909   C CG  . ARG A 1 115 ? 155.127 169.859 176.832 1.00 39.07  ? 140 ARG A CG  1 
ATOM   910   C CD  . ARG A 1 115 ? 155.809 171.020 177.536 1.00 39.07  ? 140 ARG A CD  1 
ATOM   911   N NE  . ARG A 1 115 ? 154.902 172.146 177.738 1.00 39.07  ? 140 ARG A NE  1 
ATOM   912   C CZ  . ARG A 1 115 ? 154.757 173.151 176.881 1.00 39.07  ? 140 ARG A CZ  1 
ATOM   913   N NH1 . ARG A 1 115 ? 155.461 173.173 175.757 1.00 39.07  ? 140 ARG A NH1 1 
ATOM   914   N NH2 . ARG A 1 115 ? 153.909 174.134 177.146 1.00 39.07  ? 140 ARG A NH2 1 
ATOM   915   N N   . PRO A 1 116 ? 155.449 168.159 173.562 1.00 38.01  ? 141 PRO A N   1 
ATOM   916   C CA  . PRO A 1 116 ? 154.739 168.371 172.292 1.00 38.01  ? 141 PRO A CA  1 
ATOM   917   C C   . PRO A 1 116 ? 153.993 167.142 171.814 1.00 38.01  ? 141 PRO A C   1 
ATOM   918   O O   . PRO A 1 116 ? 153.021 167.283 171.067 1.00 38.01  ? 141 PRO A O   1 
ATOM   919   C CB  . PRO A 1 116 ? 155.860 168.761 171.318 1.00 38.01  ? 141 PRO A CB  1 
ATOM   920   C CG  . PRO A 1 116 ? 156.960 169.254 172.184 1.00 38.01  ? 141 PRO A CG  1 
ATOM   921   C CD  . PRO A 1 116 ? 156.893 168.401 173.408 1.00 38.01  ? 141 PRO A CD  1 
ATOM   922   N N   . ASN A 1 117 ? 154.411 165.941 172.221 1.00 40.35  ? 142 ASN A N   1 
ATOM   923   C CA  . ASN A 1 117 ? 153.615 164.755 171.926 1.00 40.35  ? 142 ASN A CA  1 
ATOM   924   C C   . ASN A 1 117 ? 152.255 164.833 172.607 1.00 40.35  ? 142 ASN A C   1 
ATOM   925   O O   . ASN A 1 117 ? 151.231 164.486 172.009 1.00 40.35  ? 142 ASN A O   1 
ATOM   926   C CB  . ASN A 1 117 ? 154.364 163.495 172.357 1.00 40.35  ? 142 ASN A CB  1 
ATOM   927   C CG  . ASN A 1 117 ? 155.561 163.199 171.477 1.00 40.35  ? 142 ASN A CG  1 
ATOM   928   O OD1 . ASN A 1 117 ? 155.559 163.506 170.285 1.00 40.35  ? 142 ASN A OD1 1 
ATOM   929   N ND2 . ASN A 1 117 ? 156.591 162.601 172.062 1.00 40.35  ? 142 ASN A ND2 1 
ATOM   930   N N   . ILE A 1 118 ? 152.225 165.303 173.856 1.00 31.37  ? 143 ILE A N   1 
ATOM   931   C CA  . ILE A 1 118 ? 150.954 165.494 174.550 1.00 31.37  ? 143 ILE A CA  1 
ATOM   932   C C   . ILE A 1 118 ? 150.125 166.564 173.851 1.00 31.37  ? 143 ILE A C   1 
ATOM   933   O O   . ILE A 1 118 ? 148.902 166.429 173.703 1.00 31.37  ? 143 ILE A O   1 
ATOM   934   C CB  . ILE A 1 118 ? 151.201 165.846 176.028 1.00 31.37  ? 143 ILE A CB  1 
ATOM   935   C CG1 . ILE A 1 118 ? 152.068 164.777 176.694 1.00 31.37  ? 143 ILE A CG1 1 
ATOM   936   C CG2 . ILE A 1 118 ? 149.883 166.001 176.768 1.00 31.37  ? 143 ILE A CG2 1 
ATOM   937   C CD1 . ILE A 1 118 ? 152.478 165.119 178.107 1.00 31.37  ? 143 ILE A CD1 1 
ATOM   938   N N   . LEU A 1 119 ? 150.776 167.645 173.411 1.00 29.40  ? 144 LEU A N   1 
ATOM   939   C CA  . LEU A 1 119 ? 150.054 168.693 172.692 1.00 29.40  ? 144 LEU A CA  1 
ATOM   940   C C   . LEU A 1 119 ? 149.429 168.152 171.408 1.00 29.40  ? 144 LEU A C   1 
ATOM   941   O O   . LEU A 1 119 ? 148.262 168.431 171.100 1.00 29.40  ? 144 LEU A O   1 
ATOM   942   C CB  . LEU A 1 119 ? 150.993 169.860 172.387 1.00 29.40  ? 144 LEU A CB  1 
ATOM   943   C CG  . LEU A 1 119 ? 151.441 170.692 173.590 1.00 29.40  ? 144 LEU A CG  1 
ATOM   944   C CD1 . LEU A 1 119 ? 152.446 171.750 173.167 1.00 29.40  ? 144 LEU A CD1 1 
ATOM   945   C CD2 . LEU A 1 119 ? 150.242 171.331 174.271 1.00 29.40  ? 144 LEU A CD2 1 
ATOM   946   N N   . GLY A 1 120 ? 150.195 167.369 170.648 1.00 28.14  ? 145 GLY A N   1 
ATOM   947   C CA  . GLY A 1 120 ? 149.671 166.799 169.419 1.00 28.14  ? 145 GLY A CA  1 
ATOM   948   C C   . GLY A 1 120 ? 148.569 165.788 169.668 1.00 28.14  ? 145 GLY A C   1 
ATOM   949   O O   . GLY A 1 120 ? 147.619 165.690 168.888 1.00 28.14  ? 145 GLY A O   1 
ATOM   950   N N   . LEU A 1 121 ? 148.677 165.025 170.758 1.00 26.15  ? 146 LEU A N   1 
ATOM   951   C CA  . LEU A 1 121 ? 147.602 164.106 171.116 1.00 26.15  ? 146 LEU A CA  1 
ATOM   952   C C   . LEU A 1 121 ? 146.324 164.866 171.443 1.00 26.15  ? 146 LEU A C   1 
ATOM   953   O O   . LEU A 1 121 ? 145.230 164.457 171.038 1.00 26.15  ? 146 LEU A O   1 
ATOM   954   C CB  . LEU A 1 121 ? 148.026 163.232 172.295 1.00 26.15  ? 146 LEU A CB  1 
ATOM   955   C CG  . LEU A 1 121 ? 146.966 162.276 172.846 1.00 26.15  ? 146 LEU A CG  1 
ATOM   956   C CD1 . LEU A 1 121 ? 146.429 161.373 171.748 1.00 26.15  ? 146 LEU A CD1 1 
ATOM   957   C CD2 . LEU A 1 121 ? 147.533 161.451 173.990 1.00 26.15  ? 146 LEU A CD2 1 
ATOM   958   N N   . ARG A 1 122 ? 146.443 165.981 172.166 1.00 36.09  ? 147 ARG A N   1 
ATOM   959   C CA  . ARG A 1 122 ? 145.267 166.799 172.453 1.00 36.09  ? 147 ARG A CA  1 
ATOM   960   C C   . ARG A 1 122 ? 144.663 167.362 171.172 1.00 36.09  ? 147 ARG A C   1 
ATOM   961   O O   . ARG A 1 122 ? 143.435 167.382 171.007 1.00 36.09  ? 147 ARG A O   1 
ATOM   962   C CB  . ARG A 1 122 ? 145.635 167.927 173.415 1.00 36.09  ? 147 ARG A CB  1 
ATOM   963   C CG  . ARG A 1 122 ? 144.447 168.522 174.153 1.00 36.09  ? 147 ARG A CG  1 
ATOM   964   C CD  . ARG A 1 122 ? 144.898 169.503 175.222 1.00 36.09  ? 147 ARG A CD  1 
ATOM   965   N NE  . ARG A 1 122 ? 143.832 169.804 176.173 1.00 36.09  ? 147 ARG A NE  1 
ATOM   966   C CZ  . ARG A 1 122 ? 143.983 170.576 177.243 1.00 36.09  ? 147 ARG A CZ  1 
ATOM   967   N NH1 . ARG A 1 122 ? 142.957 170.795 178.054 1.00 36.09  ? 147 ARG A NH1 1 
ATOM   968   N NH2 . ARG A 1 122 ? 145.158 171.131 177.503 1.00 36.09  ? 147 ARG A NH2 1 
ATOM   969   N N   . ASN A 1 123 ? 145.513 167.821 170.249 1.00 29.05  ? 148 ASN A N   1 
ATOM   970   C CA  . ASN A 1 123 ? 145.011 168.341 168.980 1.00 29.05  ? 148 ASN A CA  1 
ATOM   971   C C   . ASN A 1 123 ? 144.298 167.256 168.180 1.00 29.05  ? 148 ASN A C   1 
ATOM   972   O O   . ASN A 1 123 ? 143.254 167.509 167.567 1.00 29.05  ? 148 ASN A O   1 
ATOM   973   C CB  . ASN A 1 123 ? 146.156 168.937 168.164 1.00 29.05  ? 148 ASN A CB  1 
ATOM   974   C CG  . ASN A 1 123 ? 145.745 169.270 166.744 1.00 29.05  ? 148 ASN A CG  1 
ATOM   975   O OD1 . ASN A 1 123 ? 144.658 169.794 166.506 1.00 29.05  ? 148 ASN A OD1 1 
ATOM   976   N ND2 . ASN A 1 123 ? 146.615 168.963 165.790 1.00 29.05  ? 148 ASN A ND2 1 
ATOM   977   N N   . ASN A 1 124 ? 144.847 166.040 168.174 1.00 32.26  ? 149 ASN A N   1 
ATOM   978   C CA  . ASN A 1 124 ? 144.211 164.947 167.447 1.00 32.26  ? 149 ASN A CA  1 
ATOM   979   C C   . ASN A 1 124 ? 142.894 164.544 168.099 1.00 32.26  ? 149 ASN A C   1 
ATOM   980   O O   . ASN A 1 124 ? 141.938 164.176 167.407 1.00 32.26  ? 149 ASN A O   1 
ATOM   981   C CB  . ASN A 1 124 ? 145.162 163.754 167.363 1.00 32.26  ? 149 ASN A CB  1 
ATOM   982   C CG  . ASN A 1 124 ? 144.925 162.909 166.131 1.00 32.26  ? 149 ASN A CG  1 
ATOM   983   O OD1 . ASN A 1 124 ? 143.784 162.628 165.767 1.00 32.26  ? 149 ASN A OD1 1 
ATOM   984   N ND2 . ASN A 1 124 ? 146.006 162.501 165.477 1.00 32.26  ? 149 ASN A ND2 1 
ATOM   985   N N   . ILE A 1 125 ? 142.823 164.611 169.431 1.00 30.67  ? 150 ILE A N   1 
ATOM   986   C CA  . ILE A 1 125 ? 141.565 164.342 170.121 1.00 30.67  ? 150 ILE A CA  1 
ATOM   987   C C   . ILE A 1 125 ? 140.520 165.381 169.738 1.00 30.67  ? 150 ILE A C   1 
ATOM   988   O O   . ILE A 1 125 ? 139.348 165.052 169.512 1.00 30.67  ? 150 ILE A O   1 
ATOM   989   C CB  . ILE A 1 125 ? 141.791 164.296 171.643 1.00 30.67  ? 150 ILE A CB  1 
ATOM   990   C CG1 . ILE A 1 125 ? 142.570 163.037 172.025 1.00 30.67  ? 150 ILE A CG1 1 
ATOM   991   C CG2 . ILE A 1 125 ? 140.465 164.346 172.387 1.00 30.67  ? 150 ILE A CG2 1 
ATOM   992   C CD1 . ILE A 1 125 ? 143.307 163.156 173.335 1.00 30.67  ? 150 ILE A CD1 1 
ATOM   993   N N   . TYR A 1 126 ? 140.927 166.650 169.653 1.00 31.48  ? 151 TYR A N   1 
ATOM   994   C CA  . TYR A 1 126 ? 140.001 167.687 169.205 1.00 31.48  ? 151 TYR A CA  1 
ATOM   995   C C   . TYR A 1 126 ? 139.546 167.436 167.772 1.00 31.48  ? 151 TYR A C   1 
ATOM   996   O O   . TYR A 1 126 ? 138.364 167.612 167.446 1.00 31.48  ? 151 TYR A O   1 
ATOM   997   C CB  . TYR A 1 126 ? 140.650 169.065 169.323 1.00 31.48  ? 151 TYR A CB  1 
ATOM   998   C CG  . TYR A 1 126 ? 139.941 170.133 168.521 1.00 31.48  ? 151 TYR A CG  1 
ATOM   999   C CD1 . TYR A 1 126 ? 138.707 170.627 168.925 1.00 31.48  ? 151 TYR A CD1 1 
ATOM   1000  C CD2 . TYR A 1 126 ? 140.502 170.643 167.357 1.00 31.48  ? 151 TYR A CD2 1 
ATOM   1001  C CE1 . TYR A 1 126 ? 138.054 171.601 168.194 1.00 31.48  ? 151 TYR A CE1 1 
ATOM   1002  C CE2 . TYR A 1 126 ? 139.855 171.616 166.620 1.00 31.48  ? 151 TYR A CE2 1 
ATOM   1003  C CZ  . TYR A 1 126 ? 138.633 172.092 167.043 1.00 31.48  ? 151 TYR A CZ  1 
ATOM   1004  O OH  . TYR A 1 126 ? 137.986 173.061 166.312 1.00 31.48  ? 151 TYR A OH  1 
ATOM   1005  N N   . CYS A 1 127 ? 140.474 167.034 166.900 1.00 39.69  ? 152 CYS A N   1 
ATOM   1006  C CA  . CYS A 1 127 ? 140.114 166.725 165.519 1.00 39.69  ? 152 CYS A CA  1 
ATOM   1007  C C   . CYS A 1 127 ? 139.098 165.593 165.454 1.00 39.69  ? 152 CYS A C   1 
ATOM   1008  O O   . CYS A 1 127 ? 138.132 165.661 164.686 1.00 39.69  ? 152 CYS A O   1 
ATOM   1009  C CB  . CYS A 1 127 ? 141.362 166.363 164.713 1.00 39.69  ? 152 CYS A CB  1 
ATOM   1010  S SG  . CYS A 1 127 ? 142.499 167.728 164.383 1.00 39.69  ? 152 CYS A SG  1 
ATOM   1011  N N   . MET A 1 128 ? 139.300 164.543 166.252 1.00 32.23  ? 153 MET A N   1 
ATOM   1012  C CA  . MET A 1 128 ? 138.353 163.431 166.266 1.00 32.23  ? 153 MET A CA  1 
ATOM   1013  C C   . MET A 1 128 ? 136.995 163.867 166.801 1.00 32.23  ? 153 MET A C   1 
ATOM   1014  O O   . MET A 1 128 ? 135.952 163.477 166.258 1.00 32.23  ? 153 MET A O   1 
ATOM   1015  C CB  . MET A 1 128 ? 138.913 162.277 167.098 1.00 32.23  ? 153 MET A CB  1 
ATOM   1016  C CG  . MET A 1 128 ? 137.893 161.200 167.437 1.00 32.23  ? 153 MET A CG  1 
ATOM   1017  S SD  . MET A 1 128 ? 137.364 160.255 165.996 1.00 32.23  ? 153 MET A SD  1 
ATOM   1018  C CE  . MET A 1 128 ? 138.882 159.402 165.578 1.00 32.23  ? 153 MET A CE  1 
ATOM   1019  N N   . ALA A 1 129 ? 136.987 164.674 167.865 1.00 35.94  ? 154 ALA A N   1 
ATOM   1020  C CA  . ALA A 1 129 ? 135.727 165.154 168.422 1.00 35.94  ? 154 ALA A CA  1 
ATOM   1021  C C   . ALA A 1 129 ? 134.971 166.024 167.429 1.00 35.94  ? 154 ALA A C   1 
ATOM   1022  O O   . ALA A 1 129 ? 133.735 166.013 167.407 1.00 35.94  ? 154 ALA A O   1 
ATOM   1023  C CB  . ALA A 1 129 ? 135.983 165.924 169.717 1.00 35.94  ? 154 ALA A CB  1 
ATOM   1024  N N   . GLN A 1 130 ? 135.690 166.784 166.602 1.00 50.48  ? 155 GLN A N   1 
ATOM   1025  C CA  . GLN A 1 130 ? 135.028 167.590 165.583 1.00 50.48  ? 155 GLN A CA  1 
ATOM   1026  C C   . GLN A 1 130 ? 134.590 166.752 164.389 1.00 50.48  ? 155 GLN A C   1 
ATOM   1027  O O   . GLN A 1 130 ? 133.586 167.075 163.745 1.00 50.48  ? 155 GLN A O   1 
ATOM   1028  C CB  . GLN A 1 130 ? 135.952 168.720 165.124 1.00 50.48  ? 155 GLN A CB  1 
ATOM   1029  C CG  . GLN A 1 130 ? 135.246 169.826 164.355 1.00 50.48  ? 155 GLN A CG  1 
ATOM   1030  C CD  . GLN A 1 130 ? 134.362 170.680 165.242 1.00 50.48  ? 155 GLN A CD  1 
ATOM   1031  O OE1 . GLN A 1 130 ? 133.345 171.211 164.797 1.00 50.48  ? 155 GLN A OE1 1 
ATOM   1032  N NE2 . GLN A 1 130 ? 134.748 170.819 166.506 1.00 50.48  ? 155 GLN A NE2 1 
ATOM   1033  N N   . LEU A 1 131 ? 135.321 165.678 164.083 1.00 54.08  ? 156 LEU A N   1 
ATOM   1034  C CA  . LEU A 1 131 ? 134.995 164.852 162.927 1.00 54.08  ? 156 LEU A CA  1 
ATOM   1035  C C   . LEU A 1 131 ? 133.803 163.943 163.196 1.00 54.08  ? 156 LEU A C   1 
ATOM   1036  O O   . LEU A 1 131 ? 132.999 163.690 162.291 1.00 54.08  ? 156 LEU A O   1 
ATOM   1037  C CB  . LEU A 1 131 ? 136.214 164.022 162.519 1.00 54.08  ? 156 LEU A CB  1 
ATOM   1038  C CG  . LEU A 1 131 ? 136.008 162.976 161.419 1.00 54.08  ? 156 LEU A CG  1 
ATOM   1039  C CD1 . LEU A 1 131 ? 135.571 163.635 160.119 1.00 54.08  ? 156 LEU A CD1 1 
ATOM   1040  C CD2 . LEU A 1 131 ? 137.268 162.151 161.211 1.00 54.08  ? 156 LEU A CD2 1 
ATOM   1041  N N   . LEU A 1 132 ? 133.671 163.438 164.427 1.00 52.12  ? 157 LEU A N   1 
ATOM   1042  C CA  . LEU A 1 132 ? 132.562 162.538 164.730 1.00 52.12  ? 157 LEU A CA  1 
ATOM   1043  C C   . LEU A 1 132 ? 131.217 163.230 164.536 1.00 52.12  ? 157 LEU A C   1 
ATOM   1044  O O   . LEU A 1 132 ? 130.279 162.631 163.997 1.00 52.12  ? 157 LEU A O   1 
ATOM   1045  C CB  . LEU A 1 132 ? 132.705 161.979 166.150 1.00 52.12  ? 157 LEU A CB  1 
ATOM   1046  C CG  . LEU A 1 132 ? 132.788 162.890 167.379 1.00 52.12  ? 157 LEU A CG  1 
ATOM   1047  C CD1 . LEU A 1 132 ? 131.414 163.265 167.916 1.00 52.12  ? 157 LEU A CD1 1 
ATOM   1048  C CD2 . LEU A 1 132 ? 133.614 162.214 168.463 1.00 52.12  ? 157 LEU A CD2 1 
ATOM   1049  N N   . ASP A 1 133 ? 131.113 164.492 164.949 1.00 55.10  ? 158 ASP A N   1 
ATOM   1050  C CA  . ASP A 1 133 ? 129.927 165.320 164.725 1.00 55.10  ? 158 ASP A CA  1 
ATOM   1051  C C   . ASP A 1 133 ? 128.659 164.622 165.220 1.00 55.10  ? 158 ASP A C   1 
ATOM   1052  O O   . ASP A 1 133 ? 127.734 164.331 164.460 1.00 55.10  ? 158 ASP A O   1 
ATOM   1053  C CB  . ASP A 1 133 ? 129.806 165.700 163.247 1.00 55.10  ? 158 ASP A CB  1 
ATOM   1054  C CG  . ASP A 1 133 ? 128.849 166.854 163.016 1.00 55.10  ? 158 ASP A CG  1 
ATOM   1055  O OD1 . ASP A 1 133 ? 128.383 167.451 164.009 1.00 55.10  ? 158 ASP A OD1 1 
ATOM   1056  O OD2 . ASP A 1 133 ? 128.562 167.161 161.841 1.00 55.10  ? 158 ASP A OD2 1 
ATOM   1057  N N   . ASN A 1 134 ? 128.634 164.355 166.521 1.00 60.09  ? 159 ASN A N   1 
ATOM   1058  C CA  . ASN A 1 134 ? 127.503 163.667 167.133 1.00 60.09  ? 159 ASN A CA  1 
ATOM   1059  C C   . ASN A 1 134 ? 127.067 164.359 168.420 1.00 60.09  ? 159 ASN A C   1 
ATOM   1060  O O   . ASN A 1 134 ? 125.932 164.196 168.870 1.00 60.09  ? 159 ASN A O   1 
ATOM   1061  C CB  . ASN A 1 134 ? 127.855 162.205 167.415 1.00 60.09  ? 159 ASN A CB  1 
ATOM   1062  C CG  . ASN A 1 134 ? 128.356 161.478 166.183 1.00 60.09  ? 159 ASN A CG  1 
ATOM   1063  O OD1 . ASN A 1 134 ? 129.453 160.919 166.180 1.00 60.09  ? 159 ASN A OD1 1 
ATOM   1064  N ND2 . ASN A 1 134 ? 127.554 161.486 165.124 1.00 60.09  ? 159 ASN A ND2 1 
ATOM   1065  N N   . THR A 1 154 ? 148.877 170.824 200.828 1.00 105.43 ? 179 THR A N   1 
ATOM   1066  C CA  . THR A 1 154 ? 150.294 170.681 201.140 1.00 105.43 ? 179 THR A CA  1 
ATOM   1067  C C   . THR A 1 154 ? 150.999 172.033 201.120 1.00 105.43 ? 179 THR A C   1 
ATOM   1068  O O   . THR A 1 154 ? 151.393 172.516 200.058 1.00 105.43 ? 179 THR A O   1 
ATOM   1069  C CB  . THR A 1 154 ? 150.997 169.731 200.153 1.00 105.43 ? 179 THR A CB  1 
ATOM   1070  O OG1 . THR A 1 154 ? 151.281 170.429 198.935 1.00 105.43 ? 179 THR A OG1 1 
ATOM   1071  C CG2 . THR A 1 154 ? 150.115 168.529 199.851 1.00 105.43 ? 179 THR A CG2 1 
ATOM   1072  N N   . PRO A 1 155 ? 151.150 172.647 202.296 1.00 116.51 ? 180 PRO A N   1 
ATOM   1073  C CA  . PRO A 1 155 ? 151.844 173.947 202.348 1.00 116.51 ? 180 PRO A CA  1 
ATOM   1074  C C   . PRO A 1 155 ? 153.300 173.861 201.923 1.00 116.51 ? 180 PRO A C   1 
ATOM   1075  O O   . PRO A 1 155 ? 153.754 174.664 201.097 1.00 116.51 ? 180 PRO A O   1 
ATOM   1076  C CB  . PRO A 1 155 ? 151.693 174.363 203.820 1.00 116.51 ? 180 PRO A CB  1 
ATOM   1077  C CG  . PRO A 1 155 ? 150.559 173.537 204.349 1.00 116.51 ? 180 PRO A CG  1 
ATOM   1078  C CD  . PRO A 1 155 ? 150.634 172.240 203.613 1.00 116.51 ? 180 PRO A CD  1 
ATOM   1079  N N   . ALA A 1 156 ? 154.048 172.904 202.468 1.00 109.27 ? 181 ALA A N   1 
ATOM   1080  C CA  . ALA A 1 156 ? 155.452 172.727 202.130 1.00 109.27 ? 181 ALA A CA  1 
ATOM   1081  C C   . ALA A 1 156 ? 155.776 171.242 202.084 1.00 109.27 ? 181 ALA A C   1 
ATOM   1082  O O   . ALA A 1 156 ? 155.298 170.469 202.919 1.00 109.27 ? 181 ALA A O   1 
ATOM   1083  C CB  . ALA A 1 156 ? 156.367 173.434 203.137 1.00 109.27 ? 181 ALA A CB  1 
ATOM   1084  N N   . SER A 1 157 ? 156.588 170.852 201.107 1.00 92.38  ? 182 SER A N   1 
ATOM   1085  C CA  . SER A 1 157 ? 156.996 169.469 200.926 1.00 92.38  ? 182 SER A CA  1 
ATOM   1086  C C   . SER A 1 157 ? 158.513 169.364 200.999 1.00 92.38  ? 182 SER A C   1 
ATOM   1087  O O   . SER A 1 157 ? 159.235 170.357 200.872 1.00 92.38  ? 182 SER A O   1 
ATOM   1088  C CB  . SER A 1 157 ? 156.493 168.910 199.588 1.00 92.38  ? 182 SER A CB  1 
ATOM   1089  O OG  . SER A 1 157 ? 155.077 168.888 199.545 1.00 92.38  ? 182 SER A OG  1 
ATOM   1090  N N   . ASP A 1 158 ? 158.990 168.141 201.208 1.00 83.26  ? 183 ASP A N   1 
ATOM   1091  C CA  . ASP A 1 158 ? 160.419 167.897 201.322 1.00 83.26  ? 183 ASP A CA  1 
ATOM   1092  C C   . ASP A 1 158 ? 161.047 167.703 199.946 1.00 83.26  ? 183 ASP A C   1 
ATOM   1093  O O   . ASP A 1 158 ? 160.399 167.247 198.997 1.00 83.26  ? 183 ASP A O   1 
ATOM   1094  C CB  . ASP A 1 158 ? 160.687 166.671 202.195 1.00 83.26  ? 183 ASP A CB  1 
ATOM   1095  C CG  . ASP A 1 158 ? 162.105 166.634 202.729 1.00 83.26  ? 183 ASP A CG  1 
ATOM   1096  O OD1 . ASP A 1 158 ? 162.860 167.598 202.481 1.00 83.26  ? 183 ASP A OD1 1 
ATOM   1097  O OD2 . ASP A 1 158 ? 162.465 165.642 203.397 1.00 83.26  ? 183 ASP A OD2 1 
ATOM   1098  N N   . ALA A 1 159 ? 162.330 168.064 199.848 1.00 61.25  ? 184 ALA A N   1 
ATOM   1099  C CA  . ALA A 1 159 ? 163.053 167.898 198.592 1.00 61.25  ? 184 ALA A CA  1 
ATOM   1100  C C   . ALA A 1 159 ? 163.120 166.432 198.185 1.00 61.25  ? 184 ALA A C   1 
ATOM   1101  O O   . ALA A 1 159 ? 163.049 166.106 196.994 1.00 61.25  ? 184 ALA A O   1 
ATOM   1102  C CB  . ALA A 1 159 ? 164.457 168.488 198.712 1.00 61.25  ? 184 ALA A CB  1 
ATOM   1103  N N   . PHE A 1 160 ? 163.256 165.532 199.160 1.00 38.97  ? 185 PHE A N   1 
ATOM   1104  C CA  . PHE A 1 160 ? 163.266 164.109 198.851 1.00 38.97  ? 185 PHE A CA  1 
ATOM   1105  C C   . PHE A 1 160 ? 161.861 163.563 198.637 1.00 38.97  ? 185 PHE A C   1 
ATOM   1106  O O   . PHE A 1 160 ? 161.693 162.556 197.939 1.00 38.97  ? 185 PHE A O   1 
ATOM   1107  C CB  . PHE A 1 160 ? 163.967 163.330 199.964 1.00 38.97  ? 185 PHE A CB  1 
ATOM   1108  C CG  . PHE A 1 160 ? 164.304 161.917 199.589 1.00 38.97  ? 185 PHE A CG  1 
ATOM   1109  C CD1 . PHE A 1 160 ? 165.417 161.641 198.813 1.00 38.97  ? 185 PHE A CD1 1 
ATOM   1110  C CD2 . PHE A 1 160 ? 163.506 160.866 200.007 1.00 38.97  ? 185 PHE A CD2 1 
ATOM   1111  C CE1 . PHE A 1 160 ? 165.729 160.343 198.463 1.00 38.97  ? 185 PHE A CE1 1 
ATOM   1112  C CE2 . PHE A 1 160 ? 163.813 159.566 199.660 1.00 38.97  ? 185 PHE A CE2 1 
ATOM   1113  C CZ  . PHE A 1 160 ? 164.926 159.304 198.886 1.00 38.97  ? 185 PHE A CZ  1 
ATOM   1114  N N   . GLN A 1 161 ? 160.848 164.205 199.220 1.00 44.59  ? 186 GLN A N   1 
ATOM   1115  C CA  . GLN A 1 161 ? 159.472 163.769 199.010 1.00 44.59  ? 186 GLN A CA  1 
ATOM   1116  C C   . GLN A 1 161 ? 158.963 164.144 197.625 1.00 44.59  ? 186 GLN A C   1 
ATOM   1117  O O   . GLN A 1 161 ? 158.132 163.424 197.056 1.00 44.59  ? 186 GLN A O   1 
ATOM   1118  C CB  . GLN A 1 161 ? 158.563 164.367 200.086 1.00 44.59  ? 186 GLN A CB  1 
ATOM   1119  C CG  . GLN A 1 161 ? 157.162 163.782 200.113 1.00 44.59  ? 186 GLN A CG  1 
ATOM   1120  C CD  . GLN A 1 161 ? 157.137 162.349 200.606 1.00 44.59  ? 186 GLN A CD  1 
ATOM   1121  O OE1 . GLN A 1 161 ? 156.279 161.560 200.212 1.00 44.59  ? 186 GLN A OE1 1 
ATOM   1122  N NE2 . GLN A 1 161 ? 158.080 162.006 201.476 1.00 44.59  ? 186 GLN A NE2 1 
ATOM   1123  N N   . ARG A 1 162 ? 159.446 165.259 197.071 1.00 45.15  ? 187 ARG A N   1 
ATOM   1124  C CA  . ARG A 1 162 ? 159.020 165.663 195.734 1.00 45.15  ? 187 ARG A CA  1 
ATOM   1125  C C   . ARG A 1 162 ? 159.449 164.644 194.685 1.00 45.15  ? 187 ARG A C   1 
ATOM   1126  O O   . ARG A 1 162 ? 158.726 164.403 193.710 1.00 45.15  ? 187 ARG A O   1 
ATOM   1127  C CB  . ARG A 1 162 ? 159.577 167.047 195.404 1.00 45.15  ? 187 ARG A CB  1 
ATOM   1128  C CG  . ARG A 1 162 ? 158.897 168.177 196.160 1.00 45.15  ? 187 ARG A CG  1 
ATOM   1129  C CD  . ARG A 1 162 ? 159.484 169.529 195.790 1.00 45.15  ? 187 ARG A CD  1 
ATOM   1130  N NE  . ARG A 1 162 ? 158.691 170.632 196.325 1.00 45.15  ? 187 ARG A NE  1 
ATOM   1131  C CZ  . ARG A 1 162 ? 158.911 171.211 197.501 1.00 45.15  ? 187 ARG A CZ  1 
ATOM   1132  N NH1 . ARG A 1 162 ? 159.906 170.792 198.272 1.00 45.15  ? 187 ARG A NH1 1 
ATOM   1133  N NH2 . ARG A 1 162 ? 158.138 172.208 197.907 1.00 45.15  ? 187 ARG A NH2 1 
ATOM   1134  N N   . LYS A 1 163 ? 160.616 164.022 194.873 1.00 26.14  ? 188 LYS A N   1 
ATOM   1135  C CA  . LYS A 1 163 ? 161.077 163.018 193.919 1.00 26.14  ? 188 LYS A CA  1 
ATOM   1136  C C   . LYS A 1 163 ? 160.192 161.777 193.951 1.00 26.14  ? 188 LYS A C   1 
ATOM   1137  O O   . LYS A 1 163 ? 159.861 161.210 192.900 1.00 26.14  ? 188 LYS A O   1 
ATOM   1138  C CB  . LYS A 1 163 ? 162.532 162.656 194.210 1.00 26.14  ? 188 LYS A CB  1 
ATOM   1139  C CG  . LYS A 1 163 ? 163.413 163.861 194.502 1.00 26.14  ? 188 LYS A CG  1 
ATOM   1140  C CD  . LYS A 1 163 ? 164.789 163.438 194.983 1.00 26.14  ? 188 LYS A CD  1 
ATOM   1141  C CE  . LYS A 1 163 ? 165.614 164.637 195.419 1.00 26.14  ? 188 LYS A CE  1 
ATOM   1142  N NZ  . LYS A 1 163 ? 167.006 164.249 195.779 1.00 26.14  ? 188 LYS A NZ  1 
ATOM   1143  N N   . LEU A 1 164 ? 159.791 161.343 195.148 1.00 42.77  ? 189 LEU A N   1 
ATOM   1144  C CA  . LEU A 1 164 ? 158.881 160.208 195.246 1.00 42.77  ? 189 LEU A CA  1 
ATOM   1145  C C   . LEU A 1 164 ? 157.512 160.552 194.671 1.00 42.77  ? 189 LEU A C   1 
ATOM   1146  O O   . LEU A 1 164 ? 156.861 159.707 194.039 1.00 42.77  ? 189 LEU A O   1 
ATOM   1147  C CB  . LEU A 1 164 ? 158.761 159.756 196.701 1.00 42.77  ? 189 LEU A CB  1 
ATOM   1148  C CG  . LEU A 1 164 ? 159.696 158.626 197.143 1.00 42.77  ? 189 LEU A CG  1 
ATOM   1149  C CD1 . LEU A 1 164 ? 161.154 159.042 197.027 1.00 42.77  ? 189 LEU A CD1 1 
ATOM   1150  C CD2 . LEU A 1 164 ? 159.373 158.189 198.564 1.00 42.77  ? 189 LEU A CD2 1 
ATOM   1151  N N   . GLU A 1 165 ? 157.061 161.794 194.873 1.00 48.30  ? 190 GLU A N   1 
ATOM   1152  C CA  . GLU A 1 165 ? 155.807 162.226 194.263 1.00 48.30  ? 190 GLU A CA  1 
ATOM   1153  C C   . GLU A 1 165 ? 155.898 162.192 192.742 1.00 48.30  ? 190 GLU A C   1 
ATOM   1154  O O   . GLU A 1 165 ? 154.945 161.793 192.062 1.00 48.30  ? 190 GLU A O   1 
ATOM   1155  C CB  . GLU A 1 165 ? 155.440 163.627 194.751 1.00 48.30  ? 190 GLU A CB  1 
ATOM   1156  C CG  . GLU A 1 165 ? 154.967 163.675 196.195 1.00 48.30  ? 190 GLU A CG  1 
ATOM   1157  C CD  . GLU A 1 165 ? 153.653 162.950 196.405 1.00 48.30  ? 190 GLU A CD  1 
ATOM   1158  O OE1 . GLU A 1 165 ? 152.866 162.843 195.440 1.00 48.30  ? 190 GLU A OE1 1 
ATOM   1159  O OE2 . GLU A 1 165 ? 153.408 162.485 197.538 1.00 48.30  ? 190 GLU A OE2 1 
ATOM   1160  N N   . GLY A 1 166 ? 157.041 162.606 192.193 1.00 39.11  ? 191 GLY A N   1 
ATOM   1161  C CA  . GLY A 1 166 ? 157.236 162.514 190.755 1.00 39.11  ? 191 GLY A CA  1 
ATOM   1162  C C   . GLY A 1 166 ? 157.226 161.080 190.258 1.00 39.11  ? 191 GLY A C   1 
ATOM   1163  O O   . GLY A 1 166 ? 156.623 160.775 189.226 1.00 39.11  ? 191 GLY A O   1 
ATOM   1164  N N   . CYS A 1 167 ? 157.903 160.183 190.984 1.00 42.14  ? 192 CYS A N   1 
ATOM   1165  C CA  . CYS A 1 167 ? 157.819 158.756 190.674 1.00 42.14  ? 192 CYS A CA  1 
ATOM   1166  C C   . CYS A 1 167 ? 156.374 158.281 190.605 1.00 42.14  ? 192 CYS A C   1 
ATOM   1167  O O   . CYS A 1 167 ? 155.971 157.634 189.629 1.00 42.14  ? 192 CYS A O   1 
ATOM   1168  C CB  . CYS A 1 167 ? 158.569 157.929 191.719 1.00 42.14  ? 192 CYS A CB  1 
ATOM   1169  S SG  . CYS A 1 167 ? 160.367 157.904 191.634 1.00 42.14  ? 192 CYS A SG  1 
ATOM   1170  N N   . ARG A 1 168 ? 155.591 158.575 191.644 1.00 44.84  ? 193 ARG A N   1 
ATOM   1171  C CA  . ARG A 1 168 ? 154.222 158.075 191.701 1.00 44.84  ? 193 ARG A CA  1 
ATOM   1172  C C   . ARG A 1 168 ? 153.373 158.660 190.580 1.00 44.84  ? 193 ARG A C   1 
ATOM   1173  O O   . ARG A 1 168 ? 152.588 157.943 189.944 1.00 44.84  ? 193 ARG A O   1 
ATOM   1174  C CB  . ARG A 1 168 ? 153.611 158.383 193.067 1.00 44.84  ? 193 ARG A CB  1 
ATOM   1175  C CG  . ARG A 1 168 ? 154.383 157.773 194.227 1.00 44.84  ? 193 ARG A CG  1 
ATOM   1176  C CD  . ARG A 1 168 ? 153.846 158.229 195.571 1.00 44.84  ? 193 ARG A CD  1 
ATOM   1177  N NE  . ARG A 1 168 ? 154.701 157.789 196.668 1.00 44.84  ? 193 ARG A NE  1 
ATOM   1178  C CZ  . ARG A 1 168 ? 154.641 156.584 197.224 1.00 44.84  ? 193 ARG A CZ  1 
ATOM   1179  N NH1 . ARG A 1 168 ? 155.459 156.270 198.218 1.00 44.84  ? 193 ARG A NH1 1 
ATOM   1180  N NH2 . ARG A 1 168 ? 153.765 155.691 196.785 1.00 44.84  ? 193 ARG A NH2 1 
ATOM   1181  N N   . PHE A 1 169 ? 153.533 159.958 190.306 1.00 39.78  ? 194 PHE A N   1 
ATOM   1182  C CA  . PHE A 1 169 ? 152.759 160.587 189.243 1.00 39.78  ? 194 PHE A CA  1 
ATOM   1183  C C   . PHE A 1 169 ? 153.110 160.003 187.882 1.00 39.78  ? 194 PHE A C   1 
ATOM   1184  O O   . PHE A 1 169 ? 152.219 159.735 187.066 1.00 39.78  ? 194 PHE A O   1 
ATOM   1185  C CB  . PHE A 1 169 ? 152.982 162.098 189.251 1.00 39.78  ? 194 PHE A CB  1 
ATOM   1186  C CG  . PHE A 1 169 ? 152.426 162.794 188.044 1.00 39.78  ? 194 PHE A CG  1 
ATOM   1187  C CD1 . PHE A 1 169 ? 151.059 162.864 187.837 1.00 39.78  ? 194 PHE A CD1 1 
ATOM   1188  C CD2 . PHE A 1 169 ? 153.270 163.378 187.115 1.00 39.78  ? 194 PHE A CD2 1 
ATOM   1189  C CE1 . PHE A 1 169 ? 150.542 163.505 186.726 1.00 39.78  ? 194 PHE A CE1 1 
ATOM   1190  C CE2 . PHE A 1 169 ? 152.761 164.021 186.002 1.00 39.78  ? 194 PHE A CE2 1 
ATOM   1191  C CZ  . PHE A 1 169 ? 151.395 164.085 185.807 1.00 39.78  ? 194 PHE A CZ  1 
ATOM   1192  N N   . LEU A 1 170 ? 154.402 159.788 187.618 1.00 29.01  ? 195 LEU A N   1 
ATOM   1193  C CA  . LEU A 1 170 ? 154.796 159.246 186.322 1.00 29.01  ? 195 LEU A CA  1 
ATOM   1194  C C   . LEU A 1 170 ? 154.348 157.798 186.167 1.00 29.01  ? 195 LEU A C   1 
ATOM   1195  O O   . LEU A 1 170 ? 153.953 157.381 185.071 1.00 29.01  ? 195 LEU A O   1 
ATOM   1196  C CB  . LEU A 1 170 ? 156.306 159.370 186.136 1.00 29.01  ? 195 LEU A CB  1 
ATOM   1197  C CG  . LEU A 1 170 ? 156.802 160.795 185.884 1.00 29.01  ? 195 LEU A CG  1 
ATOM   1198  C CD1 . LEU A 1 170 ? 158.272 160.796 185.516 1.00 29.01  ? 195 LEU A CD1 1 
ATOM   1199  C CD2 . LEU A 1 170 ? 155.976 161.466 184.799 1.00 29.01  ? 195 LEU A CD2 1 
ATOM   1200  N N   . HIS A 1 171 ? 154.382 157.018 187.250 1.00 52.54  ? 196 HIS A N   1 
ATOM   1201  C CA  . HIS A 1 171 ? 153.898 155.644 187.164 1.00 52.54  ? 196 HIS A CA  1 
ATOM   1202  C C   . HIS A 1 171 ? 152.396 155.606 186.911 1.00 52.54  ? 196 HIS A C   1 
ATOM   1203  O O   . HIS A 1 171 ? 151.912 154.797 186.108 1.00 52.54  ? 196 HIS A O   1 
ATOM   1204  C CB  . HIS A 1 171 ? 154.249 154.875 188.437 1.00 52.54  ? 196 HIS A CB  1 
ATOM   1205  C CG  . HIS A 1 171 ? 154.204 153.388 188.271 1.00 52.54  ? 196 HIS A CG  1 
ATOM   1206  N ND1 . HIS A 1 171 ? 153.027 152.672 188.287 1.00 52.54  ? 196 HIS A ND1 1 
ATOM   1207  C CD2 . HIS A 1 171 ? 155.192 152.482 188.078 1.00 52.54  ? 196 HIS A CD2 1 
ATOM   1208  C CE1 . HIS A 1 171 ? 153.291 151.389 188.115 1.00 52.54  ? 196 HIS A CE1 1 
ATOM   1209  N NE2 . HIS A 1 171 ? 154.598 151.247 187.986 1.00 52.54  ? 196 HIS A NE2 1 
ATOM   1210  N N   . GLY A 1 172 ? 151.640 156.479 187.581 1.00 48.13  ? 197 GLY A N   1 
ATOM   1211  C CA  . GLY A 1 172 ? 150.215 156.564 187.303 1.00 48.13  ? 197 GLY A CA  1 
ATOM   1212  C C   . GLY A 1 172 ? 149.929 156.998 185.878 1.00 48.13  ? 197 GLY A C   1 
ATOM   1213  O O   . GLY A 1 172 ? 149.000 156.497 185.238 1.00 48.13  ? 197 GLY A O   1 
ATOM   1214  N N   . TYR A 1 173 ? 150.731 157.931 185.358 1.00 48.15  ? 198 TYR A N   1 
ATOM   1215  C CA  . TYR A 1 173 ? 150.554 158.370 183.978 1.00 48.15  ? 198 TYR A CA  1 
ATOM   1216  C C   . TYR A 1 173 ? 150.843 157.240 182.999 1.00 48.15  ? 198 TYR A C   1 
ATOM   1217  O O   . TYR A 1 173 ? 150.140 157.085 181.995 1.00 48.15  ? 198 TYR A O   1 
ATOM   1218  C CB  . TYR A 1 173 ? 151.452 159.572 183.690 1.00 48.15  ? 198 TYR A CB  1 
ATOM   1219  C CG  . TYR A 1 173 ? 151.389 160.049 182.257 1.00 48.15  ? 198 TYR A CG  1 
ATOM   1220  C CD1 . TYR A 1 173 ? 150.305 160.782 181.797 1.00 48.15  ? 198 TYR A CD1 1 
ATOM   1221  C CD2 . TYR A 1 173 ? 152.413 159.764 181.365 1.00 48.15  ? 198 TYR A CD2 1 
ATOM   1222  C CE1 . TYR A 1 173 ? 150.243 161.219 180.488 1.00 48.15  ? 198 TYR A CE1 1 
ATOM   1223  C CE2 . TYR A 1 173 ? 152.359 160.196 180.055 1.00 48.15  ? 198 TYR A CE2 1 
ATOM   1224  C CZ  . TYR A 1 173 ? 151.273 160.923 179.622 1.00 48.15  ? 198 TYR A CZ  1 
ATOM   1225  O OH  . TYR A 1 173 ? 151.218 161.355 178.318 1.00 48.15  ? 198 TYR A OH  1 
ATOM   1226  N N   . HIS A 1 174 ? 151.871 156.435 183.275 1.00 82.10  ? 199 HIS A N   1 
ATOM   1227  C CA  . HIS A 1 174 ? 152.167 155.302 182.403 1.00 82.10  ? 199 HIS A CA  1 
ATOM   1228  C C   . HIS A 1 174 ? 151.061 154.256 182.463 1.00 82.10  ? 199 HIS A C   1 
ATOM   1229  O O   . HIS A 1 174 ? 150.710 153.656 181.439 1.00 82.10  ? 199 HIS A O   1 
ATOM   1230  C CB  . HIS A 1 174 ? 153.512 154.684 182.776 1.00 82.10  ? 199 HIS A CB  1 
ATOM   1231  C CG  . HIS A 1 174 ? 154.677 155.329 182.096 1.00 82.10  ? 199 HIS A CG  1 
ATOM   1232  N ND1 . HIS A 1 174 ? 154.748 155.476 180.728 1.00 82.10  ? 199 HIS A ND1 1 
ATOM   1233  C CD2 . HIS A 1 174 ? 155.818 155.861 182.593 1.00 82.10  ? 199 HIS A CD2 1 
ATOM   1234  C CE1 . HIS A 1 174 ? 155.882 156.076 180.412 1.00 82.10  ? 199 HIS A CE1 1 
ATOM   1235  N NE2 . HIS A 1 174 ? 156.550 156.318 181.525 1.00 82.10  ? 199 HIS A NE2 1 
ATOM   1236  N N   . ARG A 1 175 ? 150.501 154.022 183.652 1.00 45.33  ? 200 ARG A N   1 
ATOM   1237  C CA  . ARG A 1 175 ? 149.372 153.103 183.761 1.00 45.33  ? 200 ARG A CA  1 
ATOM   1238  C C   . ARG A 1 175 ? 148.175 153.610 182.965 1.00 45.33  ? 200 ARG A C   1 
ATOM   1239  O O   . ARG A 1 175 ? 147.507 152.836 182.268 1.00 45.33  ? 200 ARG A O   1 
ATOM   1240  C CB  . ARG A 1 175 ? 148.997 152.904 185.230 1.00 45.33  ? 200 ARG A CB  1 
ATOM   1241  C CG  . ARG A 1 175 ? 148.381 151.549 185.543 1.00 45.33  ? 200 ARG A CG  1 
ATOM   1242  C CD  . ARG A 1 175 ? 146.884 151.544 185.280 1.00 45.33  ? 200 ARG A CD  1 
ATOM   1243  N NE  . ARG A 1 175 ? 146.192 152.574 186.049 1.00 45.33  ? 200 ARG A NE  1 
ATOM   1244  C CZ  . ARG A 1 175 ? 144.882 152.792 185.996 1.00 45.33  ? 200 ARG A CZ  1 
ATOM   1245  N NH1 . ARG A 1 175 ? 144.116 152.052 185.206 1.00 45.33  ? 200 ARG A NH1 1 
ATOM   1246  N NH2 . ARG A 1 175 ? 144.337 153.751 186.731 1.00 45.33  ? 200 ARG A NH2 1 
ATOM   1247  N N   . PHE A 1 176 ? 147.891 154.912 183.054 1.00 35.19  ? 201 PHE A N   1 
ATOM   1248  C CA  . PHE A 1 176 ? 146.782 155.477 182.293 1.00 35.19  ? 201 PHE A CA  1 
ATOM   1249  C C   . PHE A 1 176 ? 147.042 155.398 180.793 1.00 35.19  ? 201 PHE A C   1 
ATOM   1250  O O   . PHE A 1 176 ? 146.113 155.177 180.007 1.00 35.19  ? 201 PHE A O   1 
ATOM   1251  C CB  . PHE A 1 176 ? 146.534 156.922 182.723 1.00 35.19  ? 201 PHE A CB  1 
ATOM   1252  C CG  . PHE A 1 176 ? 145.335 157.548 182.075 1.00 35.19  ? 201 PHE A CG  1 
ATOM   1253  C CD1 . PHE A 1 176 ? 144.056 157.181 182.456 1.00 35.19  ? 201 PHE A CD1 1 
ATOM   1254  C CD2 . PHE A 1 176 ? 145.487 158.505 181.088 1.00 35.19  ? 201 PHE A CD2 1 
ATOM   1255  C CE1 . PHE A 1 176 ? 142.950 157.756 181.862 1.00 35.19  ? 201 PHE A CE1 1 
ATOM   1256  C CE2 . PHE A 1 176 ? 144.385 159.084 180.491 1.00 35.19  ? 201 PHE A CE2 1 
ATOM   1257  C CZ  . PHE A 1 176 ? 143.115 158.709 180.878 1.00 35.19  ? 201 PHE A CZ  1 
ATOM   1258  N N   . MET A 1 177 ? 148.299 155.569 180.378 1.00 39.50  ? 202 MET A N   1 
ATOM   1259  C CA  . MET A 1 177 ? 148.630 155.444 178.963 1.00 39.50  ? 202 MET A CA  1 
ATOM   1260  C C   . MET A 1 177 ? 148.440 154.013 178.480 1.00 39.50  ? 202 MET A C   1 
ATOM   1261  O O   . MET A 1 177 ? 147.929 153.787 177.378 1.00 39.50  ? 202 MET A O   1 
ATOM   1262  C CB  . MET A 1 177 ? 150.064 155.911 178.713 1.00 39.50  ? 202 MET A CB  1 
ATOM   1263  C CG  . MET A 1 177 ? 150.236 157.420 178.738 1.00 39.50  ? 202 MET A CG  1 
ATOM   1264  S SD  . MET A 1 177 ? 149.153 158.263 177.570 1.00 39.50  ? 202 MET A SD  1 
ATOM   1265  C CE  . MET A 1 177 ? 149.641 157.480 176.036 1.00 39.50  ? 202 MET A CE  1 
ATOM   1266  N N   . HIS A 1 178 ? 148.841 153.032 179.291 1.00 46.54  ? 203 HIS A N   1 
ATOM   1267  C CA  . HIS A 1 178 ? 148.592 151.638 178.937 1.00 46.54  ? 203 HIS A CA  1 
ATOM   1268  C C   . HIS A 1 178 ? 147.098 151.356 178.835 1.00 46.54  ? 203 HIS A C   1 
ATOM   1269  O O   . HIS A 1 178 ? 146.649 150.652 177.921 1.00 46.54  ? 203 HIS A O   1 
ATOM   1270  C CB  . HIS A 1 178 ? 149.242 150.711 179.963 1.00 46.54  ? 203 HIS A CB  1 
ATOM   1271  C CG  . HIS A 1 178 ? 148.784 149.289 179.866 1.00 46.54  ? 203 HIS A CG  1 
ATOM   1272  N ND1 . HIS A 1 178 ? 149.134 148.464 178.819 1.00 46.54  ? 203 HIS A ND1 1 
ATOM   1273  C CD2 . HIS A 1 178 ? 148.000 148.547 180.684 1.00 46.54  ? 203 HIS A CD2 1 
ATOM   1274  C CE1 . HIS A 1 178 ? 148.588 147.275 178.997 1.00 46.54  ? 203 HIS A CE1 1 
ATOM   1275  N NE2 . HIS A 1 178 ? 147.894 147.299 180.121 1.00 46.54  ? 203 HIS A NE2 1 
ATOM   1276  N N   . SER A 1 179 ? 146.313 151.906 179.764 1.00 40.63  ? 204 SER A N   1 
ATOM   1277  C CA  . SER A 1 179 ? 144.869 151.696 179.734 1.00 40.63  ? 204 SER A CA  1 
ATOM   1278  C C   . SER A 1 179 ? 144.251 152.293 178.474 1.00 40.63  ? 204 SER A C   1 
ATOM   1279  O O   . SER A 1 179 ? 143.437 151.648 177.803 1.00 40.63  ? 204 SER A O   1 
ATOM   1280  C CB  . SER A 1 179 ? 144.228 152.295 180.986 1.00 40.63  ? 204 SER A CB  1 
ATOM   1281  O OG  . SER A 1 179 ? 142.839 152.018 181.028 1.00 40.63  ? 204 SER A OG  1 
ATOM   1282  N N   . VAL A 1 180 ? 144.631 153.527 178.133 1.00 39.14  ? 205 VAL A N   1 
ATOM   1283  C CA  . VAL A 1 180 ? 144.053 154.162 176.953 1.00 39.14  ? 205 VAL A CA  1 
ATOM   1284  C C   . VAL A 1 180 ? 144.543 153.483 175.678 1.00 39.14  ? 205 VAL A C   1 
ATOM   1285  O O   . VAL A 1 180 ? 143.818 153.435 174.678 1.00 39.14  ? 205 VAL A O   1 
ATOM   1286  C CB  . VAL A 1 180 ? 144.343 155.677 176.948 1.00 39.14  ? 205 VAL A CB  1 
ATOM   1287  C CG1 . VAL A 1 180 ? 145.805 155.960 176.656 1.00 39.14  ? 205 VAL A CG1 1 
ATOM   1288  C CG2 . VAL A 1 180 ? 143.451 156.387 175.942 1.00 39.14  ? 205 VAL A CG2 1 
ATOM   1289  N N   . GLY A 1 181 ? 145.752 152.917 175.693 1.00 39.55  ? 206 GLY A N   1 
ATOM   1290  C CA  . GLY A 1 181 ? 146.208 152.153 174.544 1.00 39.55  ? 206 GLY A CA  1 
ATOM   1291  C C   . GLY A 1 181 ? 145.415 150.876 174.352 1.00 39.55  ? 206 GLY A C   1 
ATOM   1292  O O   . GLY A 1 181 ? 145.035 150.533 173.228 1.00 39.55  ? 206 GLY A O   1 
ATOM   1293  N N   . ARG A 1 182 ? 145.150 150.157 175.446 1.00 48.36  ? 207 ARG A N   1 
ATOM   1294  C CA  . ARG A 1 182 ? 144.291 148.980 175.363 1.00 48.36  ? 207 ARG A CA  1 
ATOM   1295  C C   . ARG A 1 182 ? 142.894 149.355 174.882 1.00 48.36  ? 207 ARG A C   1 
ATOM   1296  O O   . ARG A 1 182 ? 142.283 148.627 174.090 1.00 48.36  ? 207 ARG A O   1 
ATOM   1297  C CB  . ARG A 1 182 ? 144.223 148.281 176.720 1.00 48.36  ? 207 ARG A CB  1 
ATOM   1298  C CG  . ARG A 1 182 ? 145.517 147.603 177.136 1.00 48.36  ? 207 ARG A CG  1 
ATOM   1299  C CD  . ARG A 1 182 ? 145.898 146.501 176.162 1.00 48.36  ? 207 ARG A CD  1 
ATOM   1300  N NE  . ARG A 1 182 ? 147.100 145.790 176.586 1.00 48.36  ? 207 ARG A NE  1 
ATOM   1301  C CZ  . ARG A 1 182 ? 147.639 144.772 175.922 1.00 48.36  ? 207 ARG A CZ  1 
ATOM   1302  N NH1 . ARG A 1 182 ? 147.082 144.342 174.798 1.00 48.36  ? 207 ARG A NH1 1 
ATOM   1303  N NH2 . ARG A 1 182 ? 148.734 144.183 176.382 1.00 48.36  ? 207 ARG A NH2 1 
ATOM   1304  N N   . VAL A 1 183 ? 142.379 150.498 175.343 1.00 43.13  ? 208 VAL A N   1 
ATOM   1305  C CA  . VAL A 1 183 ? 141.061 150.952 174.902 1.00 43.13  ? 208 VAL A CA  1 
ATOM   1306  C C   . VAL A 1 183 ? 141.064 151.210 173.401 1.00 43.13  ? 208 VAL A C   1 
ATOM   1307  O O   . VAL A 1 183 ? 140.196 150.723 172.669 1.00 43.13  ? 208 VAL A O   1 
ATOM   1308  C CB  . VAL A 1 183 ? 140.631 152.203 175.689 1.00 43.13  ? 208 VAL A CB  1 
ATOM   1309  C CG1 . VAL A 1 183 ? 139.439 152.866 175.018 1.00 43.13  ? 208 VAL A CG1 1 
ATOM   1310  C CG2 . VAL A 1 183 ? 140.298 151.838 177.124 1.00 43.13  ? 208 VAL A CG2 1 
ATOM   1311  N N   . PHE A 1 184 ? 142.048 151.977 172.920 1.00 45.99  ? 209 PHE A N   1 
ATOM   1312  C CA  . PHE A 1 184 ? 142.131 152.279 171.493 1.00 45.99  ? 209 PHE A CA  1 
ATOM   1313  C C   . PHE A 1 184 ? 142.282 151.011 170.662 1.00 45.99  ? 209 PHE A C   1 
ATOM   1314  O O   . PHE A 1 184 ? 141.708 150.903 169.572 1.00 45.99  ? 209 PHE A O   1 
ATOM   1315  C CB  . PHE A 1 184 ? 143.291 153.236 171.224 1.00 45.99  ? 209 PHE A CB  1 
ATOM   1316  C CG  . PHE A 1 184 ? 143.000 154.660 171.597 1.00 45.99  ? 209 PHE A CG  1 
ATOM   1317  C CD1 . PHE A 1 184 ? 141.695 155.103 171.729 1.00 45.99  ? 209 PHE A CD1 1 
ATOM   1318  C CD2 . PHE A 1 184 ? 144.032 155.555 171.820 1.00 45.99  ? 209 PHE A CD2 1 
ATOM   1319  C CE1 . PHE A 1 184 ? 141.424 156.414 172.071 1.00 45.99  ? 209 PHE A CE1 1 
ATOM   1320  C CE2 . PHE A 1 184 ? 143.768 156.867 172.165 1.00 45.99  ? 209 PHE A CE2 1 
ATOM   1321  C CZ  . PHE A 1 184 ? 142.462 157.296 172.291 1.00 45.99  ? 209 PHE A CZ  1 
ATOM   1322  N N   . SER A 1 185 ? 143.049 150.038 171.158 1.00 52.24  ? 210 SER A N   1 
ATOM   1323  C CA  . SER A 1 185 ? 143.192 148.779 170.438 1.00 52.24  ? 210 SER A CA  1 
ATOM   1324  C C   . SER A 1 185 ? 141.938 147.919 170.524 1.00 52.24  ? 210 SER A C   1 
ATOM   1325  O O   . SER A 1 185 ? 141.780 146.997 169.717 1.00 52.24  ? 210 SER A O   1 
ATOM   1326  C CB  . SER A 1 185 ? 144.395 148.001 170.969 1.00 52.24  ? 210 SER A CB  1 
ATOM   1327  O OG  . SER A 1 185 ? 144.809 147.011 170.043 1.00 52.24  ? 210 SER A OG  1 
ATOM   1328  N N   . LYS A 1 186 ? 141.049 148.195 171.481 1.00 63.62  ? 211 LYS A N   1 
ATOM   1329  C CA  . LYS A 1 186 ? 139.826 147.407 171.607 1.00 63.62  ? 211 LYS A CA  1 
ATOM   1330  C C   . LYS A 1 186 ? 138.884 147.657 170.435 1.00 63.62  ? 211 LYS A C   1 
ATOM   1331  O O   . LYS A 1 186 ? 138.550 146.735 169.682 1.00 63.62  ? 211 LYS A O   1 
ATOM   1332  C CB  . LYS A 1 186 ? 139.136 147.721 172.936 1.00 63.62  ? 211 LYS A CB  1 
ATOM   1333  C CG  . LYS A 1 186 ? 137.823 146.983 173.143 1.00 63.62  ? 211 LYS A CG  1 
ATOM   1334  C CD  . LYS A 1 186 ? 138.040 145.480 173.215 1.00 63.62  ? 211 LYS A CD  1 
ATOM   1335  C CE  . LYS A 1 186 ? 138.897 145.102 174.413 1.00 63.62  ? 211 LYS A CE  1 
ATOM   1336  N NZ  . LYS A 1 186 ? 138.278 145.534 175.696 1.00 63.62  ? 211 LYS A NZ  1 
ATOM   1337  N N   . TRP A 1 187 ? 138.443 148.901 170.261 1.00 57.26  ? 212 TRP A N   1 
ATOM   1338  C CA  . TRP A 1 187 ? 137.506 149.231 169.194 1.00 57.26  ? 212 TRP A CA  1 
ATOM   1339  C C   . TRP A 1 187 ? 138.275 149.503 167.905 1.00 57.26  ? 212 TRP A C   1 
ATOM   1340  O O   . TRP A 1 187 ? 139.100 150.422 167.845 1.00 57.26  ? 212 TRP A O   1 
ATOM   1341  C CB  . TRP A 1 187 ? 136.638 150.428 169.586 1.00 57.26  ? 212 TRP A CB  1 
ATOM   1342  C CG  . TRP A 1 187 ? 137.390 151.701 169.863 1.00 57.26  ? 212 TRP A CG  1 
ATOM   1343  C CD1 . TRP A 1 187 ? 138.250 151.936 170.892 1.00 57.26  ? 212 TRP A CD1 1 
ATOM   1344  C CD2 . TRP A 1 187 ? 137.314 152.924 169.118 1.00 57.26  ? 212 TRP A CD2 1 
ATOM   1345  N NE1 . TRP A 1 187 ? 138.734 153.220 170.825 1.00 57.26  ? 212 TRP A NE1 1 
ATOM   1346  C CE2 . TRP A 1 187 ? 138.172 153.849 169.746 1.00 57.26  ? 212 TRP A CE2 1 
ATOM   1347  C CE3 . TRP A 1 187 ? 136.611 153.324 167.978 1.00 57.26  ? 212 TRP A CE3 1 
ATOM   1348  C CZ2 . TRP A 1 187 ? 138.346 155.147 169.273 1.00 57.26  ? 212 TRP A CZ2 1 
ATOM   1349  C CZ3 . TRP A 1 187 ? 136.785 154.614 167.509 1.00 57.26  ? 212 TRP A CZ3 1 
ATOM   1350  C CH2 . TRP A 1 187 ? 137.646 155.510 168.156 1.00 57.26  ? 212 TRP A CH2 1 
ATOM   1351  N N   . GLY A 1 188 ? 138.016 148.692 166.882 1.00 65.88  ? 213 GLY A N   1 
ATOM   1352  C CA  . GLY A 1 188 ? 138.705 148.825 165.614 1.00 65.88  ? 213 GLY A CA  1 
ATOM   1353  C C   . GLY A 1 188 ? 138.167 149.940 164.742 1.00 65.88  ? 213 GLY A C   1 
ATOM   1354  O O   . GLY A 1 188 ? 138.887 150.893 164.428 1.00 65.88  ? 213 GLY A O   1 
ATOM   1355  N N   . GLU A 1 189 ? 136.902 149.832 164.340 1.00 60.21  ? 214 GLU A N   1 
ATOM   1356  C CA  . GLU A 1 189 ? 136.276 150.826 163.481 1.00 60.21  ? 214 GLU A CA  1 
ATOM   1357  C C   . GLU A 1 189 ? 134.898 151.170 164.028 1.00 60.21  ? 214 GLU A C   1 
ATOM   1358  O O   . GLU A 1 189 ? 134.292 150.399 164.776 1.00 60.21  ? 214 GLU A O   1 
ATOM   1359  C CB  . GLU A 1 189 ? 136.163 150.334 162.031 1.00 60.21  ? 214 GLU A CB  1 
ATOM   1360  C CG  . GLU A 1 189 ? 137.494 149.986 161.384 1.00 60.21  ? 214 GLU A CG  1 
ATOM   1361  C CD  . GLU A 1 189 ? 137.378 149.783 159.887 1.00 60.21  ? 214 GLU A CD  1 
ATOM   1362  O OE1 . GLU A 1 189 ? 137.918 150.617 159.130 1.00 60.21  ? 214 GLU A OE1 1 
ATOM   1363  O OE2 . GLU A 1 189 ? 136.747 148.791 159.468 1.00 60.21  ? 214 GLU A OE2 1 
ATOM   1364  N N   . SER A 1 190 ? 134.408 152.350 163.640 1.00 62.47  ? 215 SER A N   1 
ATOM   1365  C CA  . SER A 1 190 ? 133.106 152.840 164.061 1.00 62.47  ? 215 SER A CA  1 
ATOM   1366  C C   . SER A 1 190 ? 132.574 153.787 162.998 1.00 62.47  ? 215 SER A C   1 
ATOM   1367  O O   . SER A 1 190 ? 133.337 154.619 162.484 1.00 62.47  ? 215 SER A O   1 
ATOM   1368  C CB  . SER A 1 190 ? 133.173 153.560 165.413 1.00 62.47  ? 215 SER A CB  1 
ATOM   1369  O OG  . SER A 1 190 ? 133.882 152.793 166.371 1.00 62.47  ? 215 SER A OG  1 
ATOM   1370  N N   . PRO A 1 191 ? 131.283 153.693 162.646 1.00 57.65  ? 216 PRO A N   1 
ATOM   1371  C CA  . PRO A 1 191 ? 130.680 154.554 161.623 1.00 57.65  ? 216 PRO A CA  1 
ATOM   1372  C C   . PRO A 1 191 ? 130.562 156.006 162.074 1.00 57.65  ? 216 PRO A C   1 
ATOM   1373  O O   . PRO A 1 191 ? 131.243 156.861 161.509 1.00 57.65  ? 216 PRO A O   1 
ATOM   1374  C CB  . PRO A 1 191 ? 129.297 153.934 161.417 1.00 57.65  ? 216 PRO A CB  1 
ATOM   1375  C CG  . PRO A 1 191 ? 128.992 153.270 162.712 1.00 57.65  ? 216 PRO A CG  1 
ATOM   1376  C CD  . PRO A 1 191 ? 130.306 152.752 163.221 1.00 57.65  ? 216 PRO A CD  1 
ATOM   1377  N N   . PRO B 2 5   ? 166.066 227.112 150.610 1.00 248.08 ? 27  PRO B N   1 
ATOM   1378  C CA  . PRO B 2 5   ? 165.037 226.314 149.934 1.00 248.08 ? 27  PRO B CA  1 
ATOM   1379  C C   . PRO B 2 5   ? 163.683 227.015 149.899 1.00 248.08 ? 27  PRO B C   1 
ATOM   1380  O O   . PRO B 2 5   ? 163.304 227.671 150.869 1.00 248.08 ? 27  PRO B O   1 
ATOM   1381  C CB  . PRO B 2 5   ? 164.971 225.041 150.782 1.00 248.08 ? 27  PRO B CB  1 
ATOM   1382  C CG  . PRO B 2 5   ? 165.404 225.477 152.137 1.00 248.08 ? 27  PRO B CG  1 
ATOM   1383  C CD  . PRO B 2 5   ? 166.442 226.541 151.915 1.00 248.08 ? 27  PRO B CD  1 
ATOM   1384  N N   . CYS B 2 6   ? 162.965 226.877 148.783 1.00 247.61 ? 28  CYS B N   1 
ATOM   1385  C CA  . CYS B 2 6   ? 161.658 227.499 148.628 1.00 247.61 ? 28  CYS B CA  1 
ATOM   1386  C C   . CYS B 2 6   ? 160.600 226.575 148.044 1.00 247.61 ? 28  CYS B C   1 
ATOM   1387  O O   . CYS B 2 6   ? 159.419 226.939 148.061 1.00 247.61 ? 28  CYS B O   1 
ATOM   1388  C CB  . CYS B 2 6   ? 161.762 228.752 147.744 1.00 247.61 ? 28  CYS B CB  1 
ATOM   1389  S SG  . CYS B 2 6   ? 160.381 229.909 147.912 1.00 247.61 ? 28  CYS B SG  1 
ATOM   1390  N N   . GLY B 2 7   ? 160.972 225.398 147.534 1.00 265.46 ? 29  GLY B N   1 
ATOM   1391  C CA  . GLY B 2 7   ? 160.010 224.499 146.937 1.00 265.46 ? 29  GLY B CA  1 
ATOM   1392  C C   . GLY B 2 7   ? 160.313 223.055 147.280 1.00 265.46 ? 29  GLY B C   1 
ATOM   1393  O O   . GLY B 2 7   ? 161.391 222.722 147.780 1.00 265.46 ? 29  GLY B O   1 
ATOM   1394  N N   . TYR B 2 8   ? 159.333 222.200 147.000 1.00 287.48 ? 30  TYR B N   1 
ATOM   1395  C CA  . TYR B 2 8   ? 159.455 220.772 147.252 1.00 287.48 ? 30  TYR B CA  1 
ATOM   1396  C C   . TYR B 2 8   ? 158.511 220.033 146.316 1.00 287.48 ? 30  TYR B C   1 
ATOM   1397  O O   . TYR B 2 8   ? 157.395 220.493 146.063 1.00 287.48 ? 30  TYR B O   1 
ATOM   1398  C CB  . TYR B 2 8   ? 159.140 220.430 148.714 1.00 287.48 ? 30  TYR B CB  1 
ATOM   1399  C CG  . TYR B 2 8   ? 157.740 220.806 149.151 1.00 287.48 ? 30  TYR B CG  1 
ATOM   1400  C CD1 . TYR B 2 8   ? 157.447 222.095 149.578 1.00 287.48 ? 30  TYR B CD1 1 
ATOM   1401  C CD2 . TYR B 2 8   ? 156.713 219.870 149.140 1.00 287.48 ? 30  TYR B CD2 1 
ATOM   1402  C CE1 . TYR B 2 8   ? 156.170 222.442 149.978 1.00 287.48 ? 30  TYR B CE1 1 
ATOM   1403  C CE2 . TYR B 2 8   ? 155.434 220.208 149.538 1.00 287.48 ? 30  TYR B CE2 1 
ATOM   1404  C CZ  . TYR B 2 8   ? 155.168 221.495 149.957 1.00 287.48 ? 30  TYR B CZ  1 
ATOM   1405  O OH  . TYR B 2 8   ? 153.896 221.836 150.355 1.00 287.48 ? 30  TYR B OH  1 
ATOM   1406  N N   . ILE B 2 9   ? 158.965 218.893 145.806 1.00 288.93 ? 31  ILE B N   1 
ATOM   1407  C CA  . ILE B 2 9   ? 158.186 218.074 144.885 1.00 288.93 ? 31  ILE B CA  1 
ATOM   1408  C C   . ILE B 2 9   ? 157.573 216.924 145.671 1.00 288.93 ? 31  ILE B C   1 
ATOM   1409  O O   . ILE B 2 9   ? 158.294 216.118 146.272 1.00 288.93 ? 31  ILE B O   1 
ATOM   1410  C CB  . ILE B 2 9   ? 159.050 217.554 143.726 1.00 288.93 ? 31  ILE B CB  1 
ATOM   1411  C CG1 . ILE B 2 9   ? 159.836 218.702 143.089 1.00 288.93 ? 31  ILE B CG1 1 
ATOM   1412  C CG2 . ILE B 2 9   ? 158.184 216.858 142.687 1.00 288.93 ? 31  ILE B CG2 1 
ATOM   1413  C CD1 . ILE B 2 9   ? 160.780 218.262 141.993 1.00 288.93 ? 31  ILE B CD1 1 
ATOM   1414  N N   . SER B 2 10  ? 156.239 216.850 145.674 1.00 294.92 ? 32  SER B N   1 
ATOM   1415  C CA  . SER B 2 10  ? 155.533 215.798 146.395 1.00 294.92 ? 32  SER B CA  1 
ATOM   1416  C C   . SER B 2 10  ? 155.038 214.740 145.423 1.00 294.92 ? 32  SER B C   1 
ATOM   1417  O O   . SER B 2 10  ? 154.453 215.089 144.387 1.00 294.92 ? 32  SER B O   1 
ATOM   1418  C CB  . SER B 2 10  ? 154.356 216.379 147.173 1.00 294.92 ? 32  SER B CB  1 
ATOM   1419  O OG  . SER B 2 10  ? 153.643 217.322 146.393 1.00 294.92 ? 32  SER B OG  1 
ATOM   1420  N N   . PRO B 2 11  ? 155.246 213.444 145.706 1.00 293.87 ? 33  PRO B N   1 
ATOM   1421  C CA  . PRO B 2 11  ? 155.954 212.944 146.891 1.00 293.87 ? 33  PRO B CA  1 
ATOM   1422  C C   . PRO B 2 11  ? 157.472 213.076 146.776 1.00 293.87 ? 33  PRO B C   1 
ATOM   1423  O O   . PRO B 2 11  ? 157.986 213.344 145.689 1.00 293.87 ? 33  PRO B O   1 
ATOM   1424  C CB  . PRO B 2 11  ? 155.538 211.474 146.948 1.00 293.87 ? 33  PRO B CB  1 
ATOM   1425  C CG  . PRO B 2 11  ? 155.274 211.114 145.534 1.00 293.87 ? 33  PRO B CG  1 
ATOM   1426  C CD  . PRO B 2 11  ? 154.714 212.347 144.879 1.00 293.87 ? 33  PRO B CD  1 
ATOM   1427  N N   . GLU B 2 12  ? 158.174 212.885 147.894 1.00 312.27 ? 34  GLU B N   1 
ATOM   1428  C CA  . GLU B 2 12  ? 159.617 213.110 147.918 1.00 312.27 ? 34  GLU B CA  1 
ATOM   1429  C C   . GLU B 2 12  ? 160.359 212.025 147.146 1.00 312.27 ? 34  GLU B C   1 
ATOM   1430  O O   . GLU B 2 12  ? 161.056 212.309 146.165 1.00 312.27 ? 34  GLU B O   1 
ATOM   1431  C CB  . GLU B 2 12  ? 160.109 213.178 149.367 1.00 312.27 ? 34  GLU B CB  1 
ATOM   1432  C CG  . GLU B 2 12  ? 159.298 214.090 150.295 1.00 312.27 ? 34  GLU B CG  1 
ATOM   1433  C CD  . GLU B 2 12  ? 158.880 215.413 149.663 1.00 312.27 ? 34  GLU B CD  1 
ATOM   1434  O OE1 . GLU B 2 12  ? 159.656 215.985 148.866 1.00 312.27 ? 34  GLU B OE1 1 
ATOM   1435  O OE2 . GLU B 2 12  ? 157.763 215.882 149.967 1.00 312.27 ? 34  GLU B OE2 1 
ATOM   1436  N N   . SER B 2 13  ? 160.227 210.768 147.578 1.00 297.37 ? 35  SER B N   1 
ATOM   1437  C CA  . SER B 2 13  ? 160.900 209.632 146.952 1.00 297.37 ? 35  SER B CA  1 
ATOM   1438  C C   . SER B 2 13  ? 159.846 208.625 146.506 1.00 297.37 ? 35  SER B C   1 
ATOM   1439  O O   . SER B 2 13  ? 159.560 207.650 147.218 1.00 297.37 ? 35  SER B O   1 
ATOM   1440  C CB  . SER B 2 13  ? 161.908 208.987 147.904 1.00 297.37 ? 35  SER B CB  1 
ATOM   1441  O OG  . SER B 2 13  ? 162.540 207.874 147.297 1.00 297.37 ? 35  SER B OG  1 
ATOM   1442  N N   . PRO B 2 14  ? 159.248 208.827 145.335 1.00 264.36 ? 36  PRO B N   1 
ATOM   1443  C CA  . PRO B 2 14  ? 158.235 207.891 144.841 1.00 264.36 ? 36  PRO B CA  1 
ATOM   1444  C C   . PRO B 2 14  ? 158.840 206.700 144.116 1.00 264.36 ? 36  PRO B C   1 
ATOM   1445  O O   . PRO B 2 14  ? 159.858 206.798 143.428 1.00 264.36 ? 36  PRO B O   1 
ATOM   1446  C CB  . PRO B 2 14  ? 157.418 208.758 143.873 1.00 264.36 ? 36  PRO B CB  1 
ATOM   1447  C CG  . PRO B 2 14  ? 158.409 209.741 143.344 1.00 264.36 ? 36  PRO B CG  1 
ATOM   1448  C CD  . PRO B 2 14  ? 159.425 209.981 144.436 1.00 264.36 ? 36  PRO B CD  1 
ATOM   1449  N N   . VAL B 2 15  ? 158.186 205.553 144.288 1.00 221.91 ? 37  VAL B N   1 
ATOM   1450  C CA  . VAL B 2 15  ? 158.565 204.312 143.612 1.00 221.91 ? 37  VAL B CA  1 
ATOM   1451  C C   . VAL B 2 15  ? 157.301 203.792 142.932 1.00 221.91 ? 37  VAL B C   1 
ATOM   1452  O O   . VAL B 2 15  ? 156.491 203.086 143.542 1.00 221.91 ? 37  VAL B O   1 
ATOM   1453  C CB  . VAL B 2 15  ? 159.152 203.269 144.569 1.00 221.91 ? 37  VAL B CB  1 
ATOM   1454  C CG1 . VAL B 2 15  ? 159.546 202.012 143.806 1.00 221.91 ? 37  VAL B CG1 1 
ATOM   1455  C CG2 . VAL B 2 15  ? 160.349 203.842 145.312 1.00 221.91 ? 37  VAL B CG2 1 
ATOM   1456  N N   . VAL B 2 16  ? 157.122 204.143 141.664 1.00 177.66 ? 38  VAL B N   1 
ATOM   1457  C CA  . VAL B 2 16  ? 155.942 203.760 140.901 1.00 177.66 ? 38  VAL B CA  1 
ATOM   1458  C C   . VAL B 2 16  ? 156.306 202.596 139.992 1.00 177.66 ? 38  VAL B C   1 
ATOM   1459  O O   . VAL B 2 16  ? 157.465 202.424 139.596 1.00 177.66 ? 38  VAL B O   1 
ATOM   1460  C CB  . VAL B 2 16  ? 155.386 204.957 140.097 1.00 177.66 ? 38  VAL B CB  1 
ATOM   1461  C CG1 . VAL B 2 16  ? 156.345 205.352 138.982 1.00 177.66 ? 38  VAL B CG1 1 
ATOM   1462  C CG2 . VAL B 2 16  ? 153.995 204.654 139.551 1.00 177.66 ? 38  VAL B CG2 1 
ATOM   1463  N N   . GLN B 2 17  ? 155.307 201.779 139.668 1.00 163.78 ? 39  GLN B N   1 
ATOM   1464  C CA  . GLN B 2 17  ? 155.516 200.641 138.786 1.00 163.78 ? 39  GLN B CA  1 
ATOM   1465  C C   . GLN B 2 17  ? 155.896 201.111 137.385 1.00 163.78 ? 39  GLN B C   1 
ATOM   1466  O O   . GLN B 2 17  ? 155.454 202.163 136.916 1.00 163.78 ? 39  GLN B O   1 
ATOM   1467  C CB  . GLN B 2 17  ? 154.255 199.779 138.728 1.00 163.78 ? 39  GLN B CB  1 
ATOM   1468  C CG  . GLN B 2 17  ? 154.393 198.505 137.911 1.00 163.78 ? 39  GLN B CG  1 
ATOM   1469  C CD  . GLN B 2 17  ? 153.083 197.756 137.779 1.00 163.78 ? 39  GLN B CD  1 
ATOM   1470  O OE1 . GLN B 2 17  ? 152.053 198.189 138.295 1.00 163.78 ? 39  GLN B OE1 1 
ATOM   1471  N NE2 . GLN B 2 17  ? 153.115 196.627 137.081 1.00 163.78 ? 39  GLN B NE2 1 
ATOM   1472  N N   . LEU B 2 18  ? 156.735 200.319 136.722 1.00 165.04 ? 40  LEU B N   1 
ATOM   1473  C CA  . LEU B 2 18  ? 157.139 200.633 135.359 1.00 165.04 ? 40  LEU B CA  1 
ATOM   1474  C C   . LEU B 2 18  ? 155.939 200.575 134.422 1.00 165.04 ? 40  LEU B C   1 
ATOM   1475  O O   . LEU B 2 18  ? 155.068 199.710 134.556 1.00 165.04 ? 40  LEU B O   1 
ATOM   1476  C CB  . LEU B 2 18  ? 158.222 199.663 134.887 1.00 165.04 ? 40  LEU B CB  1 
ATOM   1477  C CG  . LEU B 2 18  ? 159.669 200.157 134.941 1.00 165.04 ? 40  LEU B CG  1 
ATOM   1478  C CD1 . LEU B 2 18  ? 160.063 200.539 136.359 1.00 165.04 ? 40  LEU B CD1 1 
ATOM   1479  C CD2 . LEU B 2 18  ? 160.614 199.102 134.385 1.00 165.04 ? 40  LEU B CD2 1 
ATOM   1480  N N   . HIS B 2 19  ? 155.899 201.512 133.471 1.00 174.85 ? 41  HIS B N   1 
ATOM   1481  C CA  . HIS B 2 19  ? 154.808 201.617 132.501 1.00 174.85 ? 41  HIS B CA  1 
ATOM   1482  C C   . HIS B 2 19  ? 153.461 201.779 133.204 1.00 174.85 ? 41  HIS B C   1 
ATOM   1483  O O   . HIS B 2 19  ? 152.514 201.025 132.971 1.00 174.85 ? 41  HIS B O   1 
ATOM   1484  C CB  . HIS B 2 19  ? 154.795 200.414 131.552 1.00 174.85 ? 41  HIS B CB  1 
ATOM   1485  C CG  . HIS B 2 19  ? 156.127 200.115 130.936 1.00 174.85 ? 41  HIS B CG  1 
ATOM   1486  N ND1 . HIS B 2 19  ? 157.137 199.474 131.620 1.00 174.85 ? 41  HIS B ND1 1 
ATOM   1487  C CD2 . HIS B 2 19  ? 156.613 200.368 129.698 1.00 174.85 ? 41  HIS B CD2 1 
ATOM   1488  C CE1 . HIS B 2 19  ? 158.189 199.347 130.831 1.00 174.85 ? 41  HIS B CE1 1 
ATOM   1489  N NE2 . HIS B 2 19  ? 157.897 199.881 129.658 1.00 174.85 ? 41  HIS B NE2 1 
ATOM   1490  N N   . SER B 2 20  ? 153.383 202.781 134.080 1.00 208.78 ? 42  SER B N   1 
ATOM   1491  C CA  . SER B 2 20  ? 152.166 203.029 134.842 1.00 208.78 ? 42  SER B CA  1 
ATOM   1492  C C   . SER B 2 20  ? 151.870 204.520 134.945 1.00 208.78 ? 42  SER B C   1 
ATOM   1493  O O   . SER B 2 20  ? 152.492 205.335 134.255 1.00 208.78 ? 42  SER B O   1 
ATOM   1494  C CB  . SER B 2 20  ? 152.275 202.414 136.239 1.00 208.78 ? 42  SER B CB  1 
ATOM   1495  O OG  . SER B 2 20  ? 150.998 202.281 136.840 1.00 208.78 ? 42  SER B OG  1 
ATOM   1496  N N   . ASN B 2 21  ? 150.920 204.879 135.803 1.00 274.71 ? 43  ASN B N   1 
ATOM   1497  C CA  . ASN B 2 21  ? 150.499 206.262 135.977 1.00 274.71 ? 43  ASN B CA  1 
ATOM   1498  C C   . ASN B 2 21  ? 151.253 206.903 137.135 1.00 274.71 ? 43  ASN B C   1 
ATOM   1499  O O   . ASN B 2 21  ? 151.456 206.281 138.181 1.00 274.71 ? 43  ASN B O   1 
ATOM   1500  C CB  . ASN B 2 21  ? 148.990 206.323 136.223 1.00 274.71 ? 43  ASN B CB  1 
ATOM   1501  C CG  . ASN B 2 21  ? 148.496 207.724 136.546 1.00 274.71 ? 43  ASN B CG  1 
ATOM   1502  O OD1 . ASN B 2 21  ? 148.606 208.179 137.686 1.00 274.71 ? 43  ASN B OD1 1 
ATOM   1503  N ND2 . ASN B 2 21  ? 147.934 208.415 135.551 1.00 274.71 ? 43  ASN B ND2 1 
ATOM   1504  N N   . PHE B 2 22  ? 151.665 208.155 136.941 1.00 280.02 ? 44  PHE B N   1 
ATOM   1505  C CA  . PHE B 2 22  ? 152.412 208.883 137.955 1.00 280.02 ? 44  PHE B CA  1 
ATOM   1506  C C   . PHE B 2 22  ? 152.120 210.370 137.819 1.00 280.02 ? 44  PHE B C   1 
ATOM   1507  O O   . PHE B 2 22  ? 151.867 210.870 136.720 1.00 280.02 ? 44  PHE B O   1 
ATOM   1508  C CB  . PHE B 2 22  ? 153.919 208.620 137.841 1.00 280.02 ? 44  PHE B CB  1 
ATOM   1509  C CG  . PHE B 2 22  ? 154.755 209.459 138.766 1.00 280.02 ? 44  PHE B CG  1 
ATOM   1510  C CD1 . PHE B 2 22  ? 155.520 210.504 138.274 1.00 280.02 ? 44  PHE B CD1 1 
ATOM   1511  C CD2 . PHE B 2 22  ? 154.770 209.207 140.128 1.00 280.02 ? 44  PHE B CD2 1 
ATOM   1512  C CE1 . PHE B 2 22  ? 156.288 211.279 139.123 1.00 280.02 ? 44  PHE B CE1 1 
ATOM   1513  C CE2 . PHE B 2 22  ? 155.536 209.979 140.981 1.00 280.02 ? 44  PHE B CE2 1 
ATOM   1514  C CZ  . PHE B 2 22  ? 156.296 211.016 140.478 1.00 280.02 ? 44  PHE B CZ  1 
ATOM   1515  N N   . THR B 2 23  ? 152.157 211.072 138.951 1.00 291.36 ? 45  THR B N   1 
ATOM   1516  C CA  . THR B 2 23  ? 151.895 212.505 138.991 1.00 291.36 ? 45  THR B CA  1 
ATOM   1517  C C   . THR B 2 23  ? 152.820 213.157 140.007 1.00 291.36 ? 45  THR B C   1 
ATOM   1518  O O   . THR B 2 23  ? 152.854 212.747 141.171 1.00 291.36 ? 45  THR B O   1 
ATOM   1519  C CB  . THR B 2 23  ? 150.432 212.795 139.350 1.00 291.36 ? 45  THR B CB  1 
ATOM   1520  O OG1 . THR B 2 23  ? 149.572 212.229 138.353 1.00 291.36 ? 45  THR B OG1 1 
ATOM   1521  C CG2 . THR B 2 23  ? 150.190 214.295 139.429 1.00 291.36 ? 45  THR B CG2 1 
ATOM   1522  N N   . ALA B 2 24  ? 153.563 214.168 139.565 1.00 281.77 ? 46  ALA B N   1 
ATOM   1523  C CA  . ALA B 2 24  ? 154.477 214.915 140.417 1.00 281.77 ? 46  ALA B CA  1 
ATOM   1524  C C   . ALA B 2 24  ? 153.996 216.353 140.543 1.00 281.77 ? 46  ALA B C   1 
ATOM   1525  O O   . ALA B 2 24  ? 153.556 216.959 139.561 1.00 281.77 ? 46  ALA B O   1 
ATOM   1526  C CB  . ALA B 2 24  ? 155.905 214.885 139.863 1.00 281.77 ? 46  ALA B CB  1 
ATOM   1527  N N   . VAL B 2 25  ? 154.084 216.898 141.755 1.00 282.94 ? 47  VAL B N   1 
ATOM   1528  C CA  . VAL B 2 25  ? 153.614 218.247 142.053 1.00 282.94 ? 47  VAL B CA  1 
ATOM   1529  C C   . VAL B 2 25  ? 154.726 218.989 142.780 1.00 282.94 ? 47  VAL B C   1 
ATOM   1530  O O   . VAL B 2 25  ? 155.157 218.564 143.859 1.00 282.94 ? 47  VAL B O   1 
ATOM   1531  C CB  . VAL B 2 25  ? 152.330 218.239 142.899 1.00 282.94 ? 47  VAL B CB  1 
ATOM   1532  C CG1 . VAL B 2 25  ? 151.923 219.659 143.256 1.00 282.94 ? 47  VAL B CG1 1 
ATOM   1533  C CG2 . VAL B 2 25  ? 151.206 217.525 142.163 1.00 282.94 ? 47  VAL B CG2 1 
ATOM   1534  N N   . CYS B 2 26  ? 155.183 220.096 142.198 1.00 281.73 ? 48  CYS B N   1 
ATOM   1535  C CA  . CYS B 2 26  ? 156.222 220.936 142.791 1.00 281.73 ? 48  CYS B CA  1 
ATOM   1536  C C   . CYS B 2 26  ? 155.556 222.201 143.325 1.00 281.73 ? 48  CYS B C   1 
ATOM   1537  O O   . CYS B 2 26  ? 155.147 223.074 142.556 1.00 281.73 ? 48  CYS B O   1 
ATOM   1538  C CB  . CYS B 2 26  ? 157.308 221.260 141.769 1.00 281.73 ? 48  CYS B CB  1 
ATOM   1539  S SG  . CYS B 2 26  ? 158.553 222.447 142.333 1.00 281.73 ? 48  CYS B SG  1 
ATOM   1540  N N   . VAL B 2 27  ? 155.448 222.296 144.648 1.00 274.32 ? 49  VAL B N   1 
ATOM   1541  C CA  . VAL B 2 27  ? 154.826 223.436 145.313 1.00 274.32 ? 49  VAL B CA  1 
ATOM   1542  C C   . VAL B 2 27  ? 155.923 224.352 145.835 1.00 274.32 ? 49  VAL B C   1 
ATOM   1543  O O   . VAL B 2 27  ? 156.881 223.890 146.467 1.00 274.32 ? 49  VAL B O   1 
ATOM   1544  C CB  . VAL B 2 27  ? 153.903 222.980 146.456 1.00 274.32 ? 49  VAL B CB  1 
ATOM   1545  C CG1 . VAL B 2 27  ? 153.140 224.166 147.028 1.00 274.32 ? 49  VAL B CG1 1 
ATOM   1546  C CG2 . VAL B 2 27  ? 152.943 221.908 145.967 1.00 274.32 ? 49  VAL B CG2 1 
ATOM   1547  N N   . LEU B 2 28  ? 155.785 225.648 145.575 1.00 260.97 ? 50  LEU B N   1 
ATOM   1548  C CA  . LEU B 2 28  ? 156.740 226.653 146.017 1.00 260.97 ? 50  LEU B CA  1 
ATOM   1549  C C   . LEU B 2 28  ? 156.187 227.414 147.216 1.00 260.97 ? 50  LEU B C   1 
ATOM   1550  O O   . LEU B 2 28  ? 155.001 227.333 147.547 1.00 260.97 ? 50  LEU B O   1 
ATOM   1551  C CB  . LEU B 2 28  ? 157.074 227.624 144.879 1.00 260.97 ? 50  LEU B CB  1 
ATOM   1552  C CG  . LEU B 2 28  ? 157.579 227.013 143.571 1.00 260.97 ? 50  LEU B CG  1 
ATOM   1553  C CD1 . LEU B 2 28  ? 158.013 228.105 142.606 1.00 260.97 ? 50  LEU B CD1 1 
ATOM   1554  C CD2 . LEU B 2 28  ? 158.717 226.040 143.833 1.00 260.97 ? 50  LEU B CD2 1 
ATOM   1555  N N   . LYS B 2 29  ? 157.071 228.161 147.868 1.00 251.83 ? 51  LYS B N   1 
ATOM   1556  C CA  . LYS B 2 29  ? 156.711 228.994 149.005 1.00 251.83 ? 51  LYS B CA  1 
ATOM   1557  C C   . LYS B 2 29  ? 156.586 230.452 148.577 1.00 251.83 ? 51  LYS B C   1 
ATOM   1558  O O   . LYS B 2 29  ? 157.058 230.857 147.512 1.00 251.83 ? 51  LYS B O   1 
ATOM   1559  C CB  . LYS B 2 29  ? 157.743 228.860 150.127 1.00 251.83 ? 51  LYS B CB  1 
ATOM   1560  C CG  . LYS B 2 29  ? 157.765 227.492 150.790 1.00 251.83 ? 51  LYS B CG  1 
ATOM   1561  C CD  . LYS B 2 29  ? 158.912 227.375 151.779 1.00 251.83 ? 51  LYS B CD  1 
ATOM   1562  C CE  . LYS B 2 29  ? 159.002 225.970 152.353 1.00 251.83 ? 51  LYS B CE  1 
ATOM   1563  N NZ  . LYS B 2 29  ? 159.198 224.949 151.287 1.00 251.83 ? 51  LYS B NZ  1 
ATOM   1564  N N   . GLU B 2 30  ? 155.938 231.244 149.435 1.00 235.30 ? 52  GLU B N   1 
ATOM   1565  C CA  . GLU B 2 30  ? 155.696 232.647 149.122 1.00 235.30 ? 52  GLU B CA  1 
ATOM   1566  C C   . GLU B 2 30  ? 156.967 233.487 149.171 1.00 235.30 ? 52  GLU B C   1 
ATOM   1567  O O   . GLU B 2 30  ? 156.977 234.600 148.636 1.00 235.30 ? 52  GLU B O   1 
ATOM   1568  C CB  . GLU B 2 30  ? 154.652 233.225 150.080 1.00 235.30 ? 52  GLU B CB  1 
ATOM   1569  C CG  . GLU B 2 30  ? 153.921 234.448 149.545 1.00 235.30 ? 52  GLU B CG  1 
ATOM   1570  C CD  . GLU B 2 30  ? 152.927 234.104 148.453 1.00 235.30 ? 52  GLU B CD  1 
ATOM   1571  O OE1 . GLU B 2 30  ? 152.495 232.934 148.385 1.00 235.30 ? 52  GLU B OE1 1 
ATOM   1572  O OE2 . GLU B 2 30  ? 152.578 235.003 147.660 1.00 235.30 ? 52  GLU B OE2 1 
ATOM   1573  N N   . LYS B 2 31  ? 158.034 232.980 149.794 1.00 222.47 ? 53  LYS B N   1 
ATOM   1574  C CA  . LYS B 2 31  ? 159.274 233.743 149.897 1.00 222.47 ? 53  LYS B CA  1 
ATOM   1575  C C   . LYS B 2 31  ? 159.843 234.053 148.516 1.00 222.47 ? 53  LYS B C   1 
ATOM   1576  O O   . LYS B 2 31  ? 159.980 235.220 148.131 1.00 222.47 ? 53  LYS B O   1 
ATOM   1577  C CB  . LYS B 2 31  ? 160.290 232.975 150.745 1.00 222.47 ? 53  LYS B CB  1 
ATOM   1578  C CG  . LYS B 2 31  ? 161.351 233.850 151.394 1.00 222.47 ? 53  LYS B CG  1 
ATOM   1579  C CD  . LYS B 2 31  ? 162.615 233.914 150.551 1.00 222.47 ? 53  LYS B CD  1 
ATOM   1580  C CE  . LYS B 2 31  ? 163.690 234.750 151.227 1.00 222.47 ? 53  LYS B CE  1 
ATOM   1581  N NZ  . LYS B 2 31  ? 164.941 234.803 150.422 1.00 222.47 ? 53  LYS B NZ  1 
ATOM   1582  N N   . CYS B 2 32  ? 160.181 233.013 147.752 1.00 221.24 ? 54  CYS B N   1 
ATOM   1583  C CA  . CYS B 2 32  ? 160.671 233.233 146.397 1.00 221.24 ? 54  CYS B CA  1 
ATOM   1584  C C   . CYS B 2 32  ? 159.602 233.862 145.515 1.00 221.24 ? 54  CYS B C   1 
ATOM   1585  O O   . CYS B 2 32  ? 159.928 234.584 144.565 1.00 221.24 ? 54  CYS B O   1 
ATOM   1586  C CB  . CYS B 2 32  ? 161.158 231.917 145.791 1.00 221.24 ? 54  CYS B CB  1 
ATOM   1587  S SG  . CYS B 2 32  ? 160.021 230.533 146.014 1.00 221.24 ? 54  CYS B SG  1 
ATOM   1588  N N   . MET B 2 33  ? 158.326 233.619 145.825 1.00 225.46 ? 55  MET B N   1 
ATOM   1589  C CA  . MET B 2 33  ? 157.243 234.188 145.029 1.00 225.46 ? 55  MET B CA  1 
ATOM   1590  C C   . MET B 2 33  ? 157.260 235.710 145.081 1.00 225.46 ? 55  MET B C   1 
ATOM   1591  O O   . MET B 2 33  ? 157.294 236.376 144.041 1.00 225.46 ? 55  MET B O   1 
ATOM   1592  C CB  . MET B 2 33  ? 155.897 233.645 145.510 1.00 225.46 ? 55  MET B CB  1 
ATOM   1593  C CG  . MET B 2 33  ? 155.561 232.260 144.982 1.00 225.46 ? 55  MET B CG  1 
ATOM   1594  S SD  . MET B 2 33  ? 153.942 231.687 145.527 1.00 225.46 ? 55  MET B SD  1 
ATOM   1595  C CE  . MET B 2 33  ? 152.895 233.013 144.933 1.00 225.46 ? 55  MET B CE  1 
ATOM   1596  N N   . ASP B 2 34  ? 157.238 236.282 146.283 1.00 217.26 ? 56  ASP B N   1 
ATOM   1597  C CA  . ASP B 2 34  ? 157.252 237.732 146.420 1.00 217.26 ? 56  ASP B CA  1 
ATOM   1598  C C   . ASP B 2 34  ? 158.660 238.318 146.387 1.00 217.26 ? 56  ASP B C   1 
ATOM   1599  O O   . ASP B 2 34  ? 158.804 239.543 146.440 1.00 217.26 ? 56  ASP B O   1 
ATOM   1600  C CB  . ASP B 2 34  ? 156.520 238.166 147.699 1.00 217.26 ? 56  ASP B CB  1 
ATOM   1601  C CG  . ASP B 2 34  ? 157.298 237.863 148.971 1.00 217.26 ? 56  ASP B CG  1 
ATOM   1602  O OD1 . ASP B 2 34  ? 156.923 238.410 150.030 1.00 217.26 ? 56  ASP B OD1 1 
ATOM   1603  O OD2 . ASP B 2 34  ? 158.263 237.078 148.931 1.00 217.26 ? 56  ASP B OD2 1 
ATOM   1604  N N   . TYR B 2 35  ? 159.697 237.481 146.302 1.00 190.60 ? 57  TYR B N   1 
ATOM   1605  C CA  . TYR B 2 35  ? 161.042 237.994 146.078 1.00 190.60 ? 57  TYR B CA  1 
ATOM   1606  C C   . TYR B 2 35  ? 161.343 238.164 144.592 1.00 190.60 ? 57  TYR B C   1 
ATOM   1607  O O   . TYR B 2 35  ? 161.830 239.219 144.172 1.00 190.60 ? 57  TYR B O   1 
ATOM   1608  C CB  . TYR B 2 35  ? 162.074 237.065 146.726 1.00 190.60 ? 57  TYR B CB  1 
ATOM   1609  C CG  . TYR B 2 35  ? 163.492 237.586 146.662 1.00 190.60 ? 57  TYR B CG  1 
ATOM   1610  C CD1 . TYR B 2 35  ? 164.371 237.149 145.678 1.00 190.60 ? 57  TYR B CD1 1 
ATOM   1611  C CD2 . TYR B 2 35  ? 163.954 238.517 147.584 1.00 190.60 ? 57  TYR B CD2 1 
ATOM   1612  C CE1 . TYR B 2 35  ? 165.668 237.623 145.614 1.00 190.60 ? 57  TYR B CE1 1 
ATOM   1613  C CE2 . TYR B 2 35  ? 165.250 238.997 147.528 1.00 190.60 ? 57  TYR B CE2 1 
ATOM   1614  C CZ  . TYR B 2 35  ? 166.103 238.547 146.542 1.00 190.60 ? 57  TYR B CZ  1 
ATOM   1615  O OH  . TYR B 2 35  ? 167.393 239.022 146.483 1.00 190.60 ? 57  TYR B OH  1 
ATOM   1616  N N   . PHE B 2 36  ? 161.060 237.142 143.787 1.00 193.34 ? 58  PHE B N   1 
ATOM   1617  C CA  . PHE B 2 36  ? 161.305 237.189 142.352 1.00 193.34 ? 58  PHE B CA  1 
ATOM   1618  C C   . PHE B 2 36  ? 160.087 237.636 141.555 1.00 193.34 ? 58  PHE B C   1 
ATOM   1619  O O   . PHE B 2 36  ? 160.171 237.717 140.324 1.00 193.34 ? 58  PHE B O   1 
ATOM   1620  C CB  . PHE B 2 36  ? 161.769 235.817 141.851 1.00 193.34 ? 58  PHE B CB  1 
ATOM   1621  C CG  . PHE B 2 36  ? 163.047 235.342 142.481 1.00 193.34 ? 58  PHE B CG  1 
ATOM   1622  C CD1 . PHE B 2 36  ? 164.273 235.757 141.989 1.00 193.34 ? 58  PHE B CD1 1 
ATOM   1623  C CD2 . PHE B 2 36  ? 163.023 234.477 143.562 1.00 193.34 ? 58  PHE B CD2 1 
ATOM   1624  C CE1 . PHE B 2 36  ? 165.451 235.320 142.565 1.00 193.34 ? 58  PHE B CE1 1 
ATOM   1625  C CE2 . PHE B 2 36  ? 164.197 234.036 144.142 1.00 193.34 ? 58  PHE B CE2 1 
ATOM   1626  C CZ  . PHE B 2 36  ? 165.413 234.459 143.643 1.00 193.34 ? 58  PHE B CZ  1 
ATOM   1627  N N   . HIS B 2 37  ? 158.965 237.920 142.222 1.00 206.68 ? 59  HIS B N   1 
ATOM   1628  C CA  . HIS B 2 37  ? 157.729 238.347 141.563 1.00 206.68 ? 59  HIS B CA  1 
ATOM   1629  C C   . HIS B 2 37  ? 157.257 237.301 140.552 1.00 206.68 ? 59  HIS B C   1 
ATOM   1630  O O   . HIS B 2 37  ? 156.946 237.608 139.400 1.00 206.68 ? 59  HIS B O   1 
ATOM   1631  C CB  . HIS B 2 37  ? 157.898 239.718 140.903 1.00 206.68 ? 59  HIS B CB  1 
ATOM   1632  C CG  . HIS B 2 37  ? 158.282 240.805 141.858 1.00 206.68 ? 59  HIS B CG  1 
ATOM   1633  N ND1 . HIS B 2 37  ? 158.220 240.650 143.226 1.00 206.68 ? 59  HIS B ND1 1 
ATOM   1634  C CD2 . HIS B 2 37  ? 158.735 242.063 141.643 1.00 206.68 ? 59  HIS B CD2 1 
ATOM   1635  C CE1 . HIS B 2 37  ? 158.617 241.765 143.812 1.00 206.68 ? 59  HIS B CE1 1 
ATOM   1636  N NE2 . HIS B 2 37  ? 158.935 242.639 142.874 1.00 206.68 ? 59  HIS B NE2 1 
ATOM   1637  N N   . VAL B 2 38  ? 157.207 236.048 141.000 1.00 210.41 ? 60  VAL B N   1 
ATOM   1638  C CA  . VAL B 2 38  ? 156.824 234.924 140.159 1.00 210.41 ? 60  VAL B CA  1 
ATOM   1639  C C   . VAL B 2 38  ? 155.663 234.185 140.819 1.00 210.41 ? 60  VAL B C   1 
ATOM   1640  O O   . VAL B 2 38  ? 155.266 234.477 141.947 1.00 210.41 ? 60  VAL B O   1 
ATOM   1641  C CB  . VAL B 2 38  ? 158.000 233.964 139.894 1.00 210.41 ? 60  VAL B CB  1 
ATOM   1642  C CG1 . VAL B 2 38  ? 159.174 234.713 139.283 1.00 210.41 ? 60  VAL B CG1 1 
ATOM   1643  C CG2 . VAL B 2 38  ? 158.415 233.270 141.183 1.00 210.41 ? 60  VAL B CG2 1 
ATOM   1644  N N   . ASN B 2 39  ? 155.121 233.214 140.089 1.00 222.40 ? 61  ASN B N   1 
ATOM   1645  C CA  . ASN B 2 39  ? 154.032 232.379 140.578 1.00 222.40 ? 61  ASN B CA  1 
ATOM   1646  C C   . ASN B 2 39  ? 154.162 231.001 139.938 1.00 222.40 ? 61  ASN B C   1 
ATOM   1647  O O   . ASN B 2 39  ? 155.206 230.656 139.375 1.00 222.40 ? 61  ASN B O   1 
ATOM   1648  C CB  . ASN B 2 39  ? 152.674 233.035 140.293 1.00 222.40 ? 61  ASN B CB  1 
ATOM   1649  C CG  . ASN B 2 39  ? 152.569 233.573 138.878 1.00 222.40 ? 61  ASN B CG  1 
ATOM   1650  O OD1 . ASN B 2 39  ? 153.208 233.065 137.958 1.00 222.40 ? 61  ASN B OD1 1 
ATOM   1651  N ND2 . ASN B 2 39  ? 151.757 234.608 138.699 1.00 222.40 ? 61  ASN B ND2 1 
ATOM   1652  N N   . ALA B 2 40  ? 153.093 230.206 140.024 1.00 233.51 ? 62  ALA B N   1 
ATOM   1653  C CA  . ALA B 2 40  ? 153.119 228.865 139.451 1.00 233.51 ? 62  ALA B CA  1 
ATOM   1654  C C   . ALA B 2 40  ? 153.092 228.880 137.929 1.00 233.51 ? 62  ALA B C   1 
ATOM   1655  O O   . ALA B 2 40  ? 153.419 227.863 137.308 1.00 233.51 ? 62  ALA B O   1 
ATOM   1656  C CB  . ALA B 2 40  ? 151.947 228.039 139.979 1.00 233.51 ? 62  ALA B CB  1 
ATOM   1657  N N   . ASN B 2 41  ? 152.708 230.002 137.314 1.00 220.53 ? 63  ASN B N   1 
ATOM   1658  C CA  . ASN B 2 41  ? 152.684 230.079 135.859 1.00 220.53 ? 63  ASN B CA  1 
ATOM   1659  C C   . ASN B 2 41  ? 154.081 230.053 135.254 1.00 220.53 ? 63  ASN B C   1 
ATOM   1660  O O   . ASN B 2 41  ? 154.230 229.676 134.086 1.00 220.53 ? 63  ASN B O   1 
ATOM   1661  C CB  . ASN B 2 41  ? 151.946 231.341 135.410 1.00 220.53 ? 63  ASN B CB  1 
ATOM   1662  C CG  . ASN B 2 41  ? 150.481 231.330 135.801 1.00 220.53 ? 63  ASN B CG  1 
ATOM   1663  O OD1 . ASN B 2 41  ? 149.857 230.272 135.883 1.00 220.53 ? 63  ASN B OD1 1 
ATOM   1664  N ND2 . ASN B 2 41  ? 149.924 232.510 136.043 1.00 220.53 ? 63  ASN B ND2 1 
ATOM   1665  N N   . TYR B 2 42  ? 155.102 230.441 136.014 1.00 221.16 ? 64  TYR B N   1 
ATOM   1666  C CA  . TYR B 2 42  ? 156.477 230.418 135.537 1.00 221.16 ? 64  TYR B CA  1 
ATOM   1667  C C   . TYR B 2 42  ? 157.194 229.114 135.860 1.00 221.16 ? 64  TYR B C   1 
ATOM   1668  O O   . TYR B 2 42  ? 158.374 228.973 135.521 1.00 221.16 ? 64  TYR B O   1 
ATOM   1669  C CB  . TYR B 2 42  ? 157.262 231.594 136.128 1.00 221.16 ? 64  TYR B CB  1 
ATOM   1670  C CG  . TYR B 2 42  ? 156.662 232.948 135.825 1.00 221.16 ? 64  TYR B CG  1 
ATOM   1671  C CD1 . TYR B 2 42  ? 156.726 233.490 134.549 1.00 221.16 ? 64  TYR B CD1 1 
ATOM   1672  C CD2 . TYR B 2 42  ? 156.036 233.688 136.819 1.00 221.16 ? 64  TYR B CD2 1 
ATOM   1673  C CE1 . TYR B 2 42  ? 156.180 234.729 134.270 1.00 221.16 ? 64  TYR B CE1 1 
ATOM   1674  C CE2 . TYR B 2 42  ? 155.487 234.927 136.550 1.00 221.16 ? 64  TYR B CE2 1 
ATOM   1675  C CZ  . TYR B 2 42  ? 155.563 235.443 135.274 1.00 221.16 ? 64  TYR B CZ  1 
ATOM   1676  O OH  . TYR B 2 42  ? 155.016 236.677 135.002 1.00 221.16 ? 64  TYR B OH  1 
ATOM   1677  N N   . ILE B 2 43  ? 156.519 228.163 136.506 1.00 231.02 ? 65  ILE B N   1 
ATOM   1678  C CA  . ILE B 2 43  ? 157.151 226.895 136.849 1.00 231.02 ? 65  ILE B CA  1 
ATOM   1679  C C   . ILE B 2 43  ? 157.276 226.036 135.599 1.00 231.02 ? 65  ILE B C   1 
ATOM   1680  O O   . ILE B 2 43  ? 156.284 225.756 134.914 1.00 231.02 ? 65  ILE B O   1 
ATOM   1681  C CB  . ILE B 2 43  ? 156.352 226.171 137.942 1.00 231.02 ? 65  ILE B CB  1 
ATOM   1682  C CG1 . ILE B 2 43  ? 156.358 226.985 139.237 1.00 231.02 ? 65  ILE B CG1 1 
ATOM   1683  C CG2 . ILE B 2 43  ? 156.919 224.779 138.181 1.00 231.02 ? 65  ILE B CG2 1 
ATOM   1684  C CD1 . ILE B 2 43  ? 155.649 226.302 140.388 1.00 231.02 ? 65  ILE B CD1 1 
ATOM   1685  N N   . VAL B 2 44  ? 158.501 225.611 135.297 1.00 229.50 ? 66  VAL B N   1 
ATOM   1686  C CA  . VAL B 2 44  ? 158.773 224.755 134.152 1.00 229.50 ? 66  VAL B CA  1 
ATOM   1687  C C   . VAL B 2 44  ? 159.319 223.426 134.655 1.00 229.50 ? 66  VAL B C   1 
ATOM   1688  O O   . VAL B 2 44  ? 159.875 223.325 135.752 1.00 229.50 ? 66  VAL B O   1 
ATOM   1689  C CB  . VAL B 2 44  ? 159.753 225.406 133.153 1.00 229.50 ? 66  VAL B CB  1 
ATOM   1690  C CG1 . VAL B 2 44  ? 159.231 226.763 132.705 1.00 229.50 ? 66  VAL B CG1 1 
ATOM   1691  C CG2 . VAL B 2 44  ? 161.137 225.539 133.771 1.00 229.50 ? 66  VAL B CG2 1 
ATOM   1692  N N   . TRP B 2 45  ? 159.147 222.394 133.834 1.00 226.95 ? 67  TRP B N   1 
ATOM   1693  C CA  . TRP B 2 45  ? 159.599 221.047 134.151 1.00 226.95 ? 67  TRP B CA  1 
ATOM   1694  C C   . TRP B 2 45  ? 160.654 220.623 133.141 1.00 226.95 ? 67  TRP B C   1 
ATOM   1695  O O   . TRP B 2 45  ? 160.429 220.709 131.929 1.00 226.95 ? 67  TRP B O   1 
ATOM   1696  C CB  . TRP B 2 45  ? 158.430 220.058 134.145 1.00 226.95 ? 67  TRP B CB  1 
ATOM   1697  C CG  . TRP B 2 45  ? 157.290 220.470 135.024 1.00 226.95 ? 67  TRP B CG  1 
ATOM   1698  C CD1 . TRP B 2 45  ? 156.272 221.319 134.701 1.00 226.95 ? 67  TRP B CD1 1 
ATOM   1699  C CD2 . TRP B 2 45  ? 157.050 220.048 136.371 1.00 226.95 ? 67  TRP B CD2 1 
ATOM   1700  N NE1 . TRP B 2 45  ? 155.413 221.453 135.765 1.00 226.95 ? 67  TRP B NE1 1 
ATOM   1701  C CE2 . TRP B 2 45  ? 155.868 220.683 136.802 1.00 226.95 ? 67  TRP B CE2 1 
ATOM   1702  C CE3 . TRP B 2 45  ? 157.718 219.196 137.255 1.00 226.95 ? 67  TRP B CE3 1 
ATOM   1703  C CZ2 . TRP B 2 45  ? 155.341 220.493 138.078 1.00 226.95 ? 67  TRP B CZ2 1 
ATOM   1704  C CZ3 . TRP B 2 45  ? 157.194 219.009 138.521 1.00 226.95 ? 67  TRP B CZ3 1 
ATOM   1705  C CH2 . TRP B 2 45  ? 156.017 219.653 138.920 1.00 226.95 ? 67  TRP B CH2 1 
ATOM   1706  N N   . LYS B 2 46  ? 161.800 220.168 133.641 1.00 250.96 ? 68  LYS B N   1 
ATOM   1707  C CA  . LYS B 2 46  ? 162.897 219.717 132.792 1.00 250.96 ? 68  LYS B CA  1 
ATOM   1708  C C   . LYS B 2 46  ? 163.461 218.431 133.373 1.00 250.96 ? 68  LYS B C   1 
ATOM   1709  O O   . LYS B 2 46  ? 163.891 218.408 134.530 1.00 250.96 ? 68  LYS B O   1 
ATOM   1710  C CB  . LYS B 2 46  ? 163.992 220.782 132.681 1.00 250.96 ? 68  LYS B CB  1 
ATOM   1711  C CG  . LYS B 2 46  ? 163.586 222.008 131.882 1.00 250.96 ? 68  LYS B CG  1 
ATOM   1712  C CD  . LYS B 2 46  ? 164.786 222.885 131.568 1.00 250.96 ? 68  LYS B CD  1 
ATOM   1713  C CE  . LYS B 2 46  ? 164.382 224.100 130.750 1.00 250.96 ? 68  LYS B CE  1 
ATOM   1714  N NZ  . LYS B 2 46  ? 165.551 224.964 130.428 1.00 250.96 ? 68  LYS B NZ  1 
ATOM   1715  N N   . THR B 2 47  ? 163.458 217.368 132.574 1.00 301.60 ? 69  THR B N   1 
ATOM   1716  C CA  . THR B 2 47  ? 163.981 216.083 133.002 1.00 301.60 ? 69  THR B CA  1 
ATOM   1717  C C   . THR B 2 47  ? 165.476 216.001 132.704 1.00 301.60 ? 69  THR B C   1 
ATOM   1718  O O   . THR B 2 47  ? 166.091 216.943 132.198 1.00 301.60 ? 69  THR B O   1 
ATOM   1719  C CB  . THR B 2 47  ? 163.223 214.944 132.321 1.00 301.60 ? 69  THR B CB  1 
ATOM   1720  O OG1 . THR B 2 47  ? 163.028 215.257 130.937 1.00 301.60 ? 69  THR B OG1 1 
ATOM   1721  C CG2 . THR B 2 47  ? 161.869 214.735 132.984 1.00 301.60 ? 69  THR B CG2 1 
ATOM   1722  N N   . ASN B 2 48  ? 166.073 214.854 133.023 1.00 336.43 ? 70  ASN B N   1 
ATOM   1723  C CA  . ASN B 2 48  ? 167.489 214.631 132.767 1.00 336.43 ? 70  ASN B CA  1 
ATOM   1724  C C   . ASN B 2 48  ? 167.790 214.341 131.303 1.00 336.43 ? 70  ASN B C   1 
ATOM   1725  O O   . ASN B 2 48  ? 168.964 214.198 130.946 1.00 336.43 ? 70  ASN B O   1 
ATOM   1726  C CB  . ASN B 2 48  ? 168.005 213.480 133.636 1.00 336.43 ? 70  ASN B CB  1 
ATOM   1727  C CG  . ASN B 2 48  ? 169.349 213.785 134.270 1.00 336.43 ? 70  ASN B CG  1 
ATOM   1728  O OD1 . ASN B 2 48  ? 169.693 214.946 134.496 1.00 336.43 ? 70  ASN B OD1 1 
ATOM   1729  N ND2 . ASN B 2 48  ? 170.117 212.742 134.559 1.00 336.43 ? 70  ASN B ND2 1 
ATOM   1730  N N   . HIS B 2 49  ? 166.771 214.250 130.454 1.00 346.97 ? 71  HIS B N   1 
ATOM   1731  C CA  . HIS B 2 49  ? 166.952 213.973 129.034 1.00 346.97 ? 71  HIS B CA  1 
ATOM   1732  C C   . HIS B 2 49  ? 166.345 215.035 128.132 1.00 346.97 ? 71  HIS B C   1 
ATOM   1733  O O   . HIS B 2 49  ? 166.919 215.346 127.085 1.00 346.97 ? 71  HIS B O   1 
ATOM   1734  C CB  . HIS B 2 49  ? 166.351 212.604 128.681 1.00 346.97 ? 71  HIS B CB  1 
ATOM   1735  C CG  . HIS B 2 49  ? 167.108 211.445 129.253 1.00 346.97 ? 71  HIS B CG  1 
ATOM   1736  N ND1 . HIS B 2 49  ? 167.314 211.284 130.606 1.00 346.97 ? 71  HIS B ND1 1 
ATOM   1737  C CD2 . HIS B 2 49  ? 167.710 210.390 128.653 1.00 346.97 ? 71  HIS B CD2 1 
ATOM   1738  C CE1 . HIS B 2 49  ? 168.008 210.180 130.816 1.00 346.97 ? 71  HIS B CE1 1 
ATOM   1739  N NE2 . HIS B 2 49  ? 168.262 209.619 129.647 1.00 346.97 ? 71  HIS B NE2 1 
ATOM   1740  N N   . PHE B 2 50  ? 165.199 215.601 128.505 1.00 289.84 ? 72  PHE B N   1 
ATOM   1741  C CA  . PHE B 2 50  ? 164.542 216.607 127.684 1.00 289.84 ? 72  PHE B CA  1 
ATOM   1742  C C   . PHE B 2 50  ? 163.698 217.505 128.576 1.00 289.84 ? 72  PHE B C   1 
ATOM   1743  O O   . PHE B 2 50  ? 163.537 217.258 129.774 1.00 289.84 ? 72  PHE B O   1 
ATOM   1744  C CB  . PHE B 2 50  ? 163.684 215.962 126.588 1.00 289.84 ? 72  PHE B CB  1 
ATOM   1745  C CG  . PHE B 2 50  ? 162.474 215.238 127.109 1.00 289.84 ? 72  PHE B CG  1 
ATOM   1746  C CD1 . PHE B 2 50  ? 161.221 215.828 127.058 1.00 289.84 ? 72  PHE B CD1 1 
ATOM   1747  C CD2 . PHE B 2 50  ? 162.588 213.966 127.646 1.00 289.84 ? 72  PHE B CD2 1 
ATOM   1748  C CE1 . PHE B 2 50  ? 160.106 215.165 127.535 1.00 289.84 ? 72  PHE B CE1 1 
ATOM   1749  C CE2 . PHE B 2 50  ? 161.476 213.298 128.125 1.00 289.84 ? 72  PHE B CE2 1 
ATOM   1750  C CZ  . PHE B 2 50  ? 160.234 213.898 128.069 1.00 289.84 ? 72  PHE B CZ  1 
ATOM   1751  N N   . THR B 2 51  ? 163.158 218.560 127.972 1.00 233.47 ? 73  THR B N   1 
ATOM   1752  C CA  . THR B 2 51  ? 162.305 219.517 128.664 1.00 233.47 ? 73  THR B CA  1 
ATOM   1753  C C   . THR B 2 51  ? 160.844 219.150 128.443 1.00 233.47 ? 73  THR B C   1 
ATOM   1754  O O   . THR B 2 51  ? 160.413 218.953 127.302 1.00 233.47 ? 73  THR B O   1 
ATOM   1755  C CB  . THR B 2 51  ? 162.571 220.941 128.172 1.00 233.47 ? 73  THR B CB  1 
ATOM   1756  O OG1 . THR B 2 51  ? 163.904 221.330 128.526 1.00 233.47 ? 73  THR B OG1 1 
ATOM   1757  C CG2 . THR B 2 51  ? 161.582 221.917 128.792 1.00 233.47 ? 73  THR B CG2 1 
ATOM   1758  N N   . ILE B 2 52  ? 160.091 219.058 129.531 1.00 205.85 ? 74  ILE B N   1 
ATOM   1759  C CA  . ILE B 2 52  ? 158.667 218.718 129.437 1.00 205.85 ? 74  ILE B CA  1 
ATOM   1760  C C   . ILE B 2 52  ? 157.917 219.878 128.789 1.00 205.85 ? 74  ILE B C   1 
ATOM   1761  O O   . ILE B 2 52  ? 158.060 221.031 129.235 1.00 205.85 ? 74  ILE B O   1 
ATOM   1762  C CB  . ILE B 2 52  ? 158.102 218.401 130.822 1.00 205.85 ? 74  ILE B CB  1 
ATOM   1763  C CG1 . ILE B 2 52  ? 158.622 217.047 131.310 1.00 205.85 ? 74  ILE B CG1 1 
ATOM   1764  C CG2 . ILE B 2 52  ? 156.582 218.416 130.799 1.00 205.85 ? 74  ILE B CG2 1 
ATOM   1765  C CD1 . ILE B 2 52  ? 158.064 216.624 132.650 1.00 205.85 ? 74  ILE B CD1 1 
ATOM   1766  N N   . PRO B 2 53  ? 157.118 219.635 127.745 1.00 193.51 ? 75  PRO B N   1 
ATOM   1767  C CA  . PRO B 2 53  ? 156.393 220.735 127.093 1.00 193.51 ? 75  PRO B CA  1 
ATOM   1768  C C   . PRO B 2 53  ? 155.332 221.360 127.987 1.00 193.51 ? 75  PRO B C   1 
ATOM   1769  O O   . PRO B 2 53  ? 155.092 220.894 129.106 1.00 193.51 ? 75  PRO B O   1 
ATOM   1770  C CB  . PRO B 2 53  ? 155.762 220.064 125.865 1.00 193.51 ? 75  PRO B CB  1 
ATOM   1771  C CG  . PRO B 2 53  ? 156.545 218.802 125.662 1.00 193.51 ? 75  PRO B CG  1 
ATOM   1772  C CD  . PRO B 2 53  ? 156.948 218.360 127.031 1.00 193.51 ? 75  PRO B CD  1 
ATOM   1773  N N   . LYS B 2 54  ? 154.686 222.418 127.493 1.00 200.74 ? 76  LYS B N   1 
ATOM   1774  C CA  . LYS B 2 54  ? 153.685 223.120 128.289 1.00 200.74 ? 76  LYS B CA  1 
ATOM   1775  C C   . LYS B 2 54  ? 152.380 222.337 128.373 1.00 200.74 ? 76  LYS B C   1 
ATOM   1776  O O   . LYS B 2 54  ? 151.720 222.339 129.417 1.00 200.74 ? 76  LYS B O   1 
ATOM   1777  C CB  . LYS B 2 54  ? 153.436 224.512 127.706 1.00 200.74 ? 76  LYS B CB  1 
ATOM   1778  C CG  . LYS B 2 54  ? 152.953 225.537 128.721 1.00 200.74 ? 76  LYS B CG  1 
ATOM   1779  C CD  . LYS B 2 54  ? 151.435 225.620 128.752 1.00 200.74 ? 76  LYS B CD  1 
ATOM   1780  C CE  . LYS B 2 54  ? 150.961 226.666 129.748 1.00 200.74 ? 76  LYS B CE  1 
ATOM   1781  N NZ  . LYS B 2 54  ? 149.475 226.740 129.809 1.00 200.74 ? 76  LYS B NZ  1 
ATOM   1782  N N   . GLU B 2 55  ? 151.996 221.664 127.291 1.00 195.81 ? 77  GLU B N   1 
ATOM   1783  C CA  . GLU B 2 55  ? 150.742 220.922 127.238 1.00 195.81 ? 77  GLU B CA  1 
ATOM   1784  C C   . GLU B 2 55  ? 150.788 219.612 128.015 1.00 195.81 ? 77  GLU B C   1 
ATOM   1785  O O   . GLU B 2 55  ? 149.816 218.850 127.968 1.00 195.81 ? 77  GLU B O   1 
ATOM   1786  C CB  . GLU B 2 55  ? 150.359 220.646 125.781 1.00 195.81 ? 77  GLU B CB  1 
ATOM   1787  C CG  . GLU B 2 55  ? 151.436 219.932 124.977 1.00 195.81 ? 77  GLU B CG  1 
ATOM   1788  C CD  . GLU B 2 55  ? 151.275 218.424 124.993 1.00 195.81 ? 77  GLU B CD  1 
ATOM   1789  O OE1 . GLU B 2 55  ? 150.135 217.948 125.176 1.00 195.81 ? 77  GLU B OE1 1 
ATOM   1790  O OE2 . GLU B 2 55  ? 152.289 217.715 124.823 1.00 195.81 ? 77  GLU B OE2 1 
ATOM   1791  N N   . GLN B 2 56  ? 151.882 219.330 128.724 1.00 203.36 ? 78  GLN B N   1 
ATOM   1792  C CA  . GLN B 2 56  ? 152.007 218.088 129.473 1.00 203.36 ? 78  GLN B CA  1 
ATOM   1793  C C   . GLN B 2 56  ? 151.752 218.250 130.965 1.00 203.36 ? 78  GLN B C   1 
ATOM   1794  O O   . GLN B 2 56  ? 151.460 217.255 131.637 1.00 203.36 ? 78  GLN B O   1 
ATOM   1795  C CB  . GLN B 2 56  ? 153.401 217.481 129.265 1.00 203.36 ? 78  GLN B CB  1 
ATOM   1796  C CG  . GLN B 2 56  ? 153.651 216.974 127.854 1.00 203.36 ? 78  GLN B CG  1 
ATOM   1797  C CD  . GLN B 2 56  ? 152.851 215.727 127.530 1.00 203.36 ? 78  GLN B CD  1 
ATOM   1798  O OE1 . GLN B 2 56  ? 152.433 214.993 128.426 1.00 203.36 ? 78  GLN B OE1 1 
ATOM   1799  N NE2 . GLN B 2 56  ? 152.633 215.482 126.244 1.00 203.36 ? 78  GLN B NE2 1 
ATOM   1800  N N   . TYR B 2 57  ? 151.853 219.466 131.497 1.00 210.25 ? 79  TYR B N   1 
ATOM   1801  C CA  . TYR B 2 57  ? 151.594 219.723 132.905 1.00 210.25 ? 79  TYR B CA  1 
ATOM   1802  C C   . TYR B 2 57  ? 150.447 220.714 133.049 1.00 210.25 ? 79  TYR B C   1 
ATOM   1803  O O   . TYR B 2 57  ? 150.231 221.572 132.187 1.00 210.25 ? 79  TYR B O   1 
ATOM   1804  C CB  . TYR B 2 57  ? 152.847 220.254 133.620 1.00 210.25 ? 79  TYR B CB  1 
ATOM   1805  C CG  . TYR B 2 57  ? 153.280 221.640 133.197 1.00 210.25 ? 79  TYR B CG  1 
ATOM   1806  C CD1 . TYR B 2 57  ? 154.080 221.828 132.078 1.00 210.25 ? 79  TYR B CD1 1 
ATOM   1807  C CD2 . TYR B 2 57  ? 152.901 222.760 133.926 1.00 210.25 ? 79  TYR B CD2 1 
ATOM   1808  C CE1 . TYR B 2 57  ? 154.483 223.092 131.693 1.00 210.25 ? 79  TYR B CE1 1 
ATOM   1809  C CE2 . TYR B 2 57  ? 153.298 224.027 133.547 1.00 210.25 ? 79  TYR B CE2 1 
ATOM   1810  C CZ  . TYR B 2 57  ? 154.088 224.188 132.430 1.00 210.25 ? 79  TYR B CZ  1 
ATOM   1811  O OH  . TYR B 2 57  ? 154.486 225.449 132.050 1.00 210.25 ? 79  TYR B OH  1 
ATOM   1812  N N   . THR B 2 58  ? 149.711 220.587 134.151 1.00 235.84 ? 80  THR B N   1 
ATOM   1813  C CA  . THR B 2 58  ? 148.549 221.417 134.430 1.00 235.84 ? 80  THR B CA  1 
ATOM   1814  C C   . THR B 2 58  ? 148.776 222.206 135.712 1.00 235.84 ? 80  THR B C   1 
ATOM   1815  O O   . THR B 2 58  ? 149.211 221.651 136.726 1.00 235.84 ? 80  THR B O   1 
ATOM   1816  C CB  . THR B 2 58  ? 147.278 220.567 134.559 1.00 235.84 ? 80  THR B CB  1 
ATOM   1817  O OG1 . THR B 2 58  ? 147.105 219.781 133.373 1.00 235.84 ? 80  THR B OG1 1 
ATOM   1818  C CG2 . THR B 2 58  ? 146.057 221.454 134.753 1.00 235.84 ? 80  THR B CG2 1 
ATOM   1819  N N   . ILE B 2 59  ? 148.481 223.501 135.659 1.00 245.03 ? 81  ILE B N   1 
ATOM   1820  C CA  . ILE B 2 59  ? 148.648 224.374 136.816 1.00 245.03 ? 81  ILE B CA  1 
ATOM   1821  C C   . ILE B 2 59  ? 147.471 224.179 137.761 1.00 245.03 ? 81  ILE B C   1 
ATOM   1822  O O   . ILE B 2 59  ? 146.307 224.257 137.350 1.00 245.03 ? 81  ILE B O   1 
ATOM   1823  C CB  . ILE B 2 59  ? 148.771 225.841 136.375 1.00 245.03 ? 81  ILE B CB  1 
ATOM   1824  C CG1 . ILE B 2 59  ? 149.928 226.006 135.388 1.00 245.03 ? 81  ILE B CG1 1 
ATOM   1825  C CG2 . ILE B 2 59  ? 148.965 226.746 137.581 1.00 245.03 ? 81  ILE B CG2 1 
ATOM   1826  C CD1 . ILE B 2 59  ? 151.287 225.738 135.994 1.00 245.03 ? 81  ILE B CD1 1 
ATOM   1827  N N   . ILE B 2 60  ? 147.771 223.923 139.034 1.00 256.85 ? 82  ILE B N   1 
ATOM   1828  C CA  . ILE B 2 60  ? 146.718 223.722 140.026 1.00 256.85 ? 82  ILE B CA  1 
ATOM   1829  C C   . ILE B 2 60  ? 146.173 225.059 140.511 1.00 256.85 ? 82  ILE B C   1 
ATOM   1830  O O   . ILE B 2 60  ? 144.977 225.345 140.383 1.00 256.85 ? 82  ILE B O   1 
ATOM   1831  C CB  . ILE B 2 60  ? 147.235 222.867 141.197 1.00 256.85 ? 82  ILE B CB  1 
ATOM   1832  C CG1 . ILE B 2 60  ? 147.570 221.453 140.718 1.00 256.85 ? 82  ILE B CG1 1 
ATOM   1833  C CG2 . ILE B 2 60  ? 146.211 222.826 142.321 1.00 256.85 ? 82  ILE B CG2 1 
ATOM   1834  C CD1 . ILE B 2 60  ? 147.985 220.512 141.829 1.00 256.85 ? 82  ILE B CD1 1 
ATOM   1835  N N   . ASN B 2 61  ? 147.038 225.896 141.072 1.00 262.76 ? 83  ASN B N   1 
ATOM   1836  C CA  . ASN B 2 61  ? 146.626 227.212 141.549 1.00 262.76 ? 83  ASN B CA  1 
ATOM   1837  C C   . ASN B 2 61  ? 147.800 228.172 141.373 1.00 262.76 ? 83  ASN B C   1 
ATOM   1838  O O   . ASN B 2 61  ? 148.743 227.889 140.627 1.00 262.76 ? 83  ASN B O   1 
ATOM   1839  C CB  . ASN B 2 61  ? 146.107 227.130 142.998 1.00 262.76 ? 83  ASN B CB  1 
ATOM   1840  C CG  . ASN B 2 61  ? 147.152 226.625 143.986 1.00 262.76 ? 83  ASN B CG  1 
ATOM   1841  O OD1 . ASN B 2 61  ? 148.351 226.850 143.825 1.00 262.76 ? 83  ASN B OD1 1 
ATOM   1842  N ND2 . ASN B 2 61  ? 146.688 225.942 145.026 1.00 262.76 ? 83  ASN B ND2 1 
ATOM   1843  N N   . ARG B 2 62  ? 147.738 229.316 142.059 1.00 250.75 ? 84  ARG B N   1 
ATOM   1844  C CA  . ARG B 2 62  ? 148.758 230.348 141.911 1.00 250.75 ? 84  ARG B CA  1 
ATOM   1845  C C   . ARG B 2 62  ? 150.137 229.886 142.367 1.00 250.75 ? 84  ARG B C   1 
ATOM   1846  O O   . ARG B 2 62  ? 151.144 230.449 141.925 1.00 250.75 ? 84  ARG B O   1 
ATOM   1847  C CB  . ARG B 2 62  ? 148.342 231.600 142.689 1.00 250.75 ? 84  ARG B CB  1 
ATOM   1848  C CG  . ARG B 2 62  ? 149.199 232.829 142.420 1.00 250.75 ? 84  ARG B CG  1 
ATOM   1849  C CD  . ARG B 2 62  ? 149.047 233.861 143.526 1.00 250.75 ? 84  ARG B CD  1 
ATOM   1850  N NE  . ARG B 2 62  ? 149.951 234.993 143.345 1.00 250.75 ? 84  ARG B NE  1 
ATOM   1851  C CZ  . ARG B 2 62  ? 150.113 235.968 144.233 1.00 250.75 ? 84  ARG B CZ  1 
ATOM   1852  N NH1 . ARG B 2 62  ? 149.431 235.952 145.370 1.00 250.75 ? 84  ARG B NH1 1 
ATOM   1853  N NH2 . ARG B 2 62  ? 150.958 236.959 143.986 1.00 250.75 ? 84  ARG B NH2 1 
ATOM   1854  N N   . THR B 2 63  ? 150.213 228.873 143.236 1.00 269.82 ? 85  THR B N   1 
ATOM   1855  C CA  . THR B 2 63  ? 151.493 228.427 143.777 1.00 269.82 ? 85  THR B CA  1 
ATOM   1856  C C   . THR B 2 63  ? 151.682 226.917 143.662 1.00 269.82 ? 85  THR B C   1 
ATOM   1857  O O   . THR B 2 63  ? 152.430 226.333 144.454 1.00 269.82 ? 85  THR B O   1 
ATOM   1858  C CB  . THR B 2 63  ? 151.642 228.860 145.239 1.00 269.82 ? 85  THR B CB  1 
ATOM   1859  O OG1 . THR B 2 63  ? 152.865 228.339 145.773 1.00 269.82 ? 85  THR B OG1 1 
ATOM   1860  C CG2 . THR B 2 63  ? 150.472 228.351 146.068 1.00 269.82 ? 85  THR B CG2 1 
ATOM   1861  N N   . ALA B 2 64  ? 151.033 226.272 142.696 1.00 267.07 ? 86  ALA B N   1 
ATOM   1862  C CA  . ALA B 2 64  ? 151.151 224.831 142.529 1.00 267.07 ? 86  ALA B CA  1 
ATOM   1863  C C   . ALA B 2 64  ? 151.141 224.477 141.049 1.00 267.07 ? 86  ALA B C   1 
ATOM   1864  O O   . ALA B 2 64  ? 150.476 225.129 140.241 1.00 267.07 ? 86  ALA B O   1 
ATOM   1865  C CB  . ALA B 2 64  ? 150.024 224.084 143.251 1.00 267.07 ? 86  ALA B CB  1 
ATOM   1866  N N   . SER B 2 65  ? 151.886 223.427 140.708 1.00 258.63 ? 87  SER B N   1 
ATOM   1867  C CA  . SER B 2 65  ? 151.954 222.915 139.348 1.00 258.63 ? 87  SER B CA  1 
ATOM   1868  C C   . SER B 2 65  ? 152.088 221.401 139.400 1.00 258.63 ? 87  SER B C   1 
ATOM   1869  O O   . SER B 2 65  ? 152.852 220.867 140.208 1.00 258.63 ? 87  SER B O   1 
ATOM   1870  C CB  . SER B 2 65  ? 153.129 223.525 138.574 1.00 258.63 ? 87  SER B CB  1 
ATOM   1871  O OG  . SER B 2 65  ? 153.116 224.939 138.657 1.00 258.63 ? 87  SER B OG  1 
ATOM   1872  N N   . SER B 2 66  ? 151.344 220.715 138.536 1.00 255.05 ? 88  SER B N   1 
ATOM   1873  C CA  . SER B 2 66  ? 151.295 219.260 138.519 1.00 255.05 ? 88  SER B CA  1 
ATOM   1874  C C   . SER B 2 66  ? 151.614 218.750 137.122 1.00 255.05 ? 88  SER B C   1 
ATOM   1875  O O   . SER B 2 66  ? 151.071 219.254 136.133 1.00 255.05 ? 88  SER B O   1 
ATOM   1876  C CB  . SER B 2 66  ? 149.920 218.752 138.964 1.00 255.05 ? 88  SER B CB  1 
ATOM   1877  O OG  . SER B 2 66  ? 149.028 218.668 137.866 1.00 255.05 ? 88  SER B OG  1 
ATOM   1878  N N   . VAL B 2 67  ? 152.488 217.748 137.047 1.00 250.40 ? 89  VAL B N   1 
ATOM   1879  C CA  . VAL B 2 67  ? 152.853 217.105 135.792 1.00 250.40 ? 89  VAL B CA  1 
ATOM   1880  C C   . VAL B 2 67  ? 152.496 215.628 135.889 1.00 250.40 ? 89  VAL B C   1 
ATOM   1881  O O   . VAL B 2 67  ? 152.435 215.055 136.982 1.00 250.40 ? 89  VAL B O   1 
ATOM   1882  C CB  . VAL B 2 67  ? 154.352 217.297 135.462 1.00 250.40 ? 89  VAL B CB  1 
ATOM   1883  C CG1 . VAL B 2 67  ? 155.218 216.391 136.328 1.00 250.40 ? 89  VAL B CG1 1 
ATOM   1884  C CG2 . VAL B 2 67  ? 154.616 217.055 133.981 1.00 250.40 ? 89  VAL B CG2 1 
ATOM   1885  N N   . THR B 2 68  ? 152.241 215.015 134.735 1.00 255.26 ? 90  THR B N   1 
ATOM   1886  C CA  . THR B 2 68  ? 151.838 213.618 134.670 1.00 255.26 ? 90  THR B CA  1 
ATOM   1887  C C   . THR B 2 68  ? 152.731 212.864 133.695 1.00 255.26 ? 90  THR B C   1 
ATOM   1888  O O   . THR B 2 68  ? 153.284 213.435 132.751 1.00 255.26 ? 90  THR B O   1 
ATOM   1889  C CB  . THR B 2 68  ? 150.369 213.473 134.247 1.00 255.26 ? 90  THR B CB  1 
ATOM   1890  O OG1 . THR B 2 68  ? 150.088 214.374 133.168 1.00 255.26 ? 90  THR B OG1 1 
ATOM   1891  C CG2 . THR B 2 68  ? 149.445 213.786 135.415 1.00 255.26 ? 90  THR B CG2 1 
ATOM   1892  N N   . PHE B 2 69  ? 152.864 211.561 133.939 1.00 234.23 ? 91  PHE B N   1 
ATOM   1893  C CA  . PHE B 2 69  ? 153.640 210.667 133.087 1.00 234.23 ? 91  PHE B CA  1 
ATOM   1894  C C   . PHE B 2 69  ? 152.776 209.467 132.735 1.00 234.23 ? 91  PHE B C   1 
ATOM   1895  O O   . PHE B 2 69  ? 152.318 208.747 133.628 1.00 234.23 ? 91  PHE B O   1 
ATOM   1896  C CB  . PHE B 2 69  ? 154.929 210.218 133.780 1.00 234.23 ? 91  PHE B CB  1 
ATOM   1897  C CG  . PHE B 2 69  ? 156.050 211.212 133.679 1.00 234.23 ? 91  PHE B CG  1 
ATOM   1898  C CD1 . PHE B 2 69  ? 157.047 211.058 132.730 1.00 234.23 ? 91  PHE B CD1 1 
ATOM   1899  C CD2 . PHE B 2 69  ? 156.107 212.300 134.534 1.00 234.23 ? 91  PHE B CD2 1 
ATOM   1900  C CE1 . PHE B 2 69  ? 158.080 211.971 132.635 1.00 234.23 ? 91  PHE B CE1 1 
ATOM   1901  C CE2 . PHE B 2 69  ? 157.137 213.216 134.444 1.00 234.23 ? 91  PHE B CE2 1 
ATOM   1902  C CZ  . PHE B 2 69  ? 158.125 213.052 133.493 1.00 234.23 ? 91  PHE B CZ  1 
ATOM   1903  N N   . THR B 2 70  ? 152.555 209.252 131.439 1.00 220.43 ? 92  THR B N   1 
ATOM   1904  C CA  . THR B 2 70  ? 151.703 208.168 130.971 1.00 220.43 ? 92  THR B CA  1 
ATOM   1905  C C   . THR B 2 70  ? 152.448 206.853 130.784 1.00 220.43 ? 92  THR B C   1 
ATOM   1906  O O   . THR B 2 70  ? 151.802 205.811 130.635 1.00 220.43 ? 92  THR B O   1 
ATOM   1907  C CB  . THR B 2 70  ? 151.030 208.554 129.649 1.00 220.43 ? 92  THR B CB  1 
ATOM   1908  O OG1 . THR B 2 70  ? 150.057 207.562 129.297 1.00 220.43 ? 92  THR B OG1 1 
ATOM   1909  C CG2 . THR B 2 70  ? 152.061 208.665 128.536 1.00 220.43 ? 92  THR B CG2 1 
ATOM   1910  N N   . ASP B 2 71  ? 153.779 206.871 130.791 1.00 186.74 ? 93  ASP B N   1 
ATOM   1911  C CA  . ASP B 2 71  ? 154.555 205.655 130.559 1.00 186.74 ? 93  ASP B CA  1 
ATOM   1912  C C   . ASP B 2 71  ? 155.935 205.838 131.167 1.00 186.74 ? 93  ASP B C   1 
ATOM   1913  O O   . ASP B 2 71  ? 156.678 206.735 130.755 1.00 186.74 ? 93  ASP B O   1 
ATOM   1914  C CB  . ASP B 2 71  ? 154.656 205.354 129.062 1.00 186.74 ? 93  ASP B CB  1 
ATOM   1915  C CG  . ASP B 2 71  ? 155.238 203.984 128.779 1.00 186.74 ? 93  ASP B CG  1 
ATOM   1916  O OD1 . ASP B 2 71  ? 155.413 203.200 129.735 1.00 186.74 ? 93  ASP B OD1 1 
ATOM   1917  O OD2 . ASP B 2 71  ? 155.521 203.690 127.599 1.00 186.74 ? 93  ASP B OD2 1 
ATOM   1918  N N   . ILE B 2 72  ? 156.277 204.997 132.138 1.00 171.28 ? 94  ILE B N   1 
ATOM   1919  C CA  . ILE B 2 72  ? 157.585 205.014 132.783 1.00 171.28 ? 94  ILE B CA  1 
ATOM   1920  C C   . ILE B 2 72  ? 158.331 203.767 132.329 1.00 171.28 ? 94  ILE B C   1 
ATOM   1921  O O   . ILE B 2 72  ? 158.034 202.654 132.780 1.00 171.28 ? 94  ILE B O   1 
ATOM   1922  C CB  . ILE B 2 72  ? 157.471 205.073 134.312 1.00 171.28 ? 94  ILE B CB  1 
ATOM   1923  C CG1 . ILE B 2 72  ? 156.813 206.384 134.748 1.00 171.28 ? 94  ILE B CG1 1 
ATOM   1924  C CG2 . ILE B 2 72  ? 158.843 204.931 134.955 1.00 171.28 ? 94  ILE B CG2 1 
ATOM   1925  C CD1 . ILE B 2 72  ? 157.611 207.618 134.386 1.00 171.28 ? 94  ILE B CD1 1 
ATOM   1926  N N   . ALA B 2 73  ? 159.299 203.950 131.430 1.00 166.33 ? 95  ALA B N   1 
ATOM   1927  C CA  . ALA B 2 73  ? 160.092 202.847 130.904 1.00 166.33 ? 95  ALA B CA  1 
ATOM   1928  C C   . ALA B 2 73  ? 161.576 202.997 131.212 1.00 166.33 ? 95  ALA B C   1 
ATOM   1929  O O   . ALA B 2 73  ? 162.389 202.227 130.688 1.00 166.33 ? 95  ALA B O   1 
ATOM   1930  C CB  . ALA B 2 73  ? 159.883 202.714 129.392 1.00 166.33 ? 95  ALA B CB  1 
ATOM   1931  N N   . SER B 2 74  ? 161.949 203.962 132.046 1.00 198.69 ? 96  SER B N   1 
ATOM   1932  C CA  . SER B 2 74  ? 163.336 204.196 132.413 1.00 198.69 ? 96  SER B CA  1 
ATOM   1933  C C   . SER B 2 74  ? 163.572 203.778 133.858 1.00 198.69 ? 96  SER B C   1 
ATOM   1934  O O   . SER B 2 74  ? 162.670 203.845 134.698 1.00 198.69 ? 96  SER B O   1 
ATOM   1935  C CB  . SER B 2 74  ? 163.714 205.669 132.229 1.00 198.69 ? 96  SER B CB  1 
ATOM   1936  O OG  . SER B 2 74  ? 164.843 206.008 133.014 1.00 198.69 ? 96  SER B OG  1 
ATOM   1937  N N   . LEU B 2 75  ? 164.800 203.342 134.140 1.00 226.88 ? 97  LEU B N   1 
ATOM   1938  C CA  . LEU B 2 75  ? 165.142 202.925 135.495 1.00 226.88 ? 97  LEU B CA  1 
ATOM   1939  C C   . LEU B 2 75  ? 165.309 204.126 136.418 1.00 226.88 ? 97  LEU B C   1 
ATOM   1940  O O   . LEU B 2 75  ? 164.908 204.074 137.586 1.00 226.88 ? 97  LEU B O   1 
ATOM   1941  C CB  . LEU B 2 75  ? 166.417 202.081 135.476 1.00 226.88 ? 97  LEU B CB  1 
ATOM   1942  C CG  . LEU B 2 75  ? 167.008 201.623 136.814 1.00 226.88 ? 97  LEU B CG  1 
ATOM   1943  C CD1 . LEU B 2 75  ? 165.933 201.044 137.727 1.00 226.88 ? 97  LEU B CD1 1 
ATOM   1944  C CD2 . LEU B 2 75  ? 168.126 200.615 136.590 1.00 226.88 ? 97  LEU B CD2 1 
ATOM   1945  N N   . ASN B 2 76  ? 165.887 205.215 135.914 1.00 254.59 ? 98  ASN B N   1 
ATOM   1946  C CA  . ASN B 2 76  ? 166.123 206.418 136.700 1.00 254.59 ? 98  ASN B CA  1 
ATOM   1947  C C   . ASN B 2 76  ? 165.671 207.636 135.908 1.00 254.59 ? 98  ASN B C   1 
ATOM   1948  O O   . ASN B 2 76  ? 166.016 207.777 134.730 1.00 254.59 ? 98  ASN B O   1 
ATOM   1949  C CB  . ASN B 2 76  ? 167.603 206.550 137.079 1.00 254.59 ? 98  ASN B CB  1 
ATOM   1950  C CG  . ASN B 2 76  ? 168.526 206.412 135.884 1.00 254.59 ? 98  ASN B CG  1 
ATOM   1951  O OD1 . ASN B 2 76  ? 168.451 205.437 135.136 1.00 254.59 ? 98  ASN B OD1 1 
ATOM   1952  N ND2 . ASN B 2 76  ? 169.404 207.391 135.698 1.00 254.59 ? 98  ASN B ND2 1 
ATOM   1953  N N   . ILE B 2 77  ? 164.898 208.507 136.555 1.00 279.11 ? 99  ILE B N   1 
ATOM   1954  C CA  . ILE B 2 77  ? 164.411 209.739 135.941 1.00 279.11 ? 99  ILE B CA  1 
ATOM   1955  C C   . ILE B 2 77  ? 164.552 210.860 136.961 1.00 279.11 ? 99  ILE B C   1 
ATOM   1956  O O   . ILE B 2 77  ? 163.955 210.797 138.042 1.00 279.11 ? 99  ILE B O   1 
ATOM   1957  C CB  . ILE B 2 77  ? 162.950 209.624 135.470 1.00 279.11 ? 99  ILE B CB  1 
ATOM   1958  C CG1 . ILE B 2 77  ? 162.859 208.751 134.218 1.00 279.11 ? 99  ILE B CG1 1 
ATOM   1959  C CG2 . ILE B 2 77  ? 162.364 211.004 135.204 1.00 279.11 ? 99  ILE B CG2 1 
ATOM   1960  C CD1 . ILE B 2 77  ? 163.570 209.331 133.015 1.00 279.11 ? 99  ILE B CD1 1 
ATOM   1961  N N   . GLN B 2 78  ? 165.338 211.880 136.625 1.00 288.99 ? 100 GLN B N   1 
ATOM   1962  C CA  . GLN B 2 78  ? 165.562 213.021 137.511 1.00 288.99 ? 100 GLN B CA  1 
ATOM   1963  C C   . GLN B 2 78  ? 164.596 214.133 137.120 1.00 288.99 ? 100 GLN B C   1 
ATOM   1964  O O   . GLN B 2 78  ? 164.860 214.906 136.196 1.00 288.99 ? 100 GLN B O   1 
ATOM   1965  C CB  . GLN B 2 78  ? 167.012 213.487 137.434 1.00 288.99 ? 100 GLN B CB  1 
ATOM   1966  C CG  . GLN B 2 78  ? 168.027 212.427 137.830 1.00 288.99 ? 100 GLN B CG  1 
ATOM   1967  C CD  . GLN B 2 78  ? 169.456 212.930 137.752 1.00 288.99 ? 100 GLN B CD  1 
ATOM   1968  O OE1 . GLN B 2 78  ? 169.702 214.082 137.395 1.00 288.99 ? 100 GLN B OE1 1 
ATOM   1969  N NE2 . GLN B 2 78  ? 170.407 212.065 138.087 1.00 288.99 ? 100 GLN B NE2 1 
ATOM   1970  N N   . LEU B 2 79  ? 163.471 214.214 137.826 1.00 255.67 ? 101 LEU B N   1 
ATOM   1971  C CA  . LEU B 2 79  ? 162.467 215.241 137.578 1.00 255.67 ? 101 LEU B CA  1 
ATOM   1972  C C   . LEU B 2 79  ? 162.778 216.461 138.437 1.00 255.67 ? 101 LEU B C   1 
ATOM   1973  O O   . LEU B 2 79  ? 162.780 216.373 139.669 1.00 255.67 ? 101 LEU B O   1 
ATOM   1974  C CB  . LEU B 2 79  ? 161.066 214.711 137.879 1.00 255.67 ? 101 LEU B CB  1 
ATOM   1975  C CG  . LEU B 2 79  ? 159.909 215.707 137.761 1.00 255.67 ? 101 LEU B CG  1 
ATOM   1976  C CD1 . LEU B 2 79  ? 158.750 215.088 137.000 1.00 255.67 ? 101 LEU B CD1 1 
ATOM   1977  C CD2 . LEU B 2 79  ? 159.451 216.177 139.135 1.00 255.67 ? 101 LEU B CD2 1 
ATOM   1978  N N   . THR B 2 80  ? 163.036 217.594 137.788 1.00 242.77 ? 102 THR B N   1 
ATOM   1979  C CA  . THR B 2 80  ? 163.383 218.830 138.476 1.00 242.77 ? 102 THR B CA  1 
ATOM   1980  C C   . THR B 2 80  ? 162.459 219.946 138.015 1.00 242.77 ? 102 THR B C   1 
ATOM   1981  O O   . THR B 2 80  ? 162.274 220.146 136.811 1.00 242.77 ? 102 THR B O   1 
ATOM   1982  C CB  . THR B 2 80  ? 164.843 219.223 138.219 1.00 242.77 ? 102 THR B CB  1 
ATOM   1983  O OG1 . THR B 2 80  ? 165.063 219.357 136.809 1.00 242.77 ? 102 THR B OG1 1 
ATOM   1984  C CG2 . THR B 2 80  ? 165.788 218.170 138.779 1.00 242.77 ? 102 THR B CG2 1 
ATOM   1985  N N   . CYS B 2 81  ? 161.884 220.667 138.973 1.00 229.40 ? 103 CYS B N   1 
ATOM   1986  C CA  . CYS B 2 81  ? 161.049 221.825 138.689 1.00 229.40 ? 103 CYS B CA  1 
ATOM   1987  C C   . CYS B 2 81  ? 161.882 223.094 138.807 1.00 229.40 ? 103 CYS B C   1 
ATOM   1988  O O   . CYS B 2 81  ? 162.664 223.251 139.749 1.00 229.40 ? 103 CYS B O   1 
ATOM   1989  C CB  . CYS B 2 81  ? 159.850 221.888 139.639 1.00 229.40 ? 103 CYS B CB  1 
ATOM   1990  S SG  . CYS B 2 81  ? 160.266 221.873 141.401 1.00 229.40 ? 103 CYS B SG  1 
ATOM   1991  N N   . ASN B 2 82  ? 161.716 223.995 137.843 1.00 226.08 ? 104 ASN B N   1 
ATOM   1992  C CA  . ASN B 2 82  ? 162.488 225.225 137.793 1.00 226.08 ? 104 ASN B CA  1 
ATOM   1993  C C   . ASN B 2 82  ? 161.552 226.416 137.652 1.00 226.08 ? 104 ASN B C   1 
ATOM   1994  O O   . ASN B 2 82  ? 160.402 226.286 137.227 1.00 226.08 ? 104 ASN B O   1 
ATOM   1995  C CB  . ASN B 2 82  ? 163.497 225.208 136.639 1.00 226.08 ? 104 ASN B CB  1 
ATOM   1996  C CG  . ASN B 2 82  ? 164.375 223.973 136.654 1.00 226.08 ? 104 ASN B CG  1 
ATOM   1997  O OD1 . ASN B 2 82  ? 165.442 223.963 137.267 1.00 226.08 ? 104 ASN B OD1 1 
ATOM   1998  N ND2 . ASN B 2 82  ? 163.927 222.921 135.978 1.00 226.08 ? 104 ASN B ND2 1 
ATOM   1999  N N   . ILE B 2 83  ? 162.067 227.587 138.018 1.00 213.34 ? 105 ILE B N   1 
ATOM   2000  C CA  . ILE B 2 83  ? 161.312 228.831 137.967 1.00 213.34 ? 105 ILE B CA  1 
ATOM   2001  C C   . ILE B 2 83  ? 161.896 229.713 136.873 1.00 213.34 ? 105 ILE B C   1 
ATOM   2002  O O   . ILE B 2 83  ? 163.073 229.597 136.511 1.00 213.34 ? 105 ILE B O   1 
ATOM   2003  C CB  . ILE B 2 83  ? 161.321 229.557 139.331 1.00 213.34 ? 105 ILE B CB  1 
ATOM   2004  C CG1 . ILE B 2 83  ? 160.176 230.569 139.415 1.00 213.34 ? 105 ILE B CG1 1 
ATOM   2005  C CG2 . ILE B 2 83  ? 162.660 230.238 139.573 1.00 213.34 ? 105 ILE B CG2 1 
ATOM   2006  C CD1 . ILE B 2 83  ? 158.801 229.951 139.281 1.00 213.34 ? 105 ILE B CD1 1 
ATOM   2007  N N   . LEU B 2 84  ? 161.055 230.589 136.330 1.00 202.50 ? 106 LEU B N   1 
ATOM   2008  C CA  . LEU B 2 84  ? 161.453 231.538 135.297 1.00 202.50 ? 106 LEU B CA  1 
ATOM   2009  C C   . LEU B 2 84  ? 161.386 232.934 135.905 1.00 202.50 ? 106 LEU B C   1 
ATOM   2010  O O   . LEU B 2 84  ? 160.295 233.463 136.144 1.00 202.50 ? 106 LEU B O   1 
ATOM   2011  C CB  . LEU B 2 84  ? 160.556 231.409 134.065 1.00 202.50 ? 106 LEU B CB  1 
ATOM   2012  C CG  . LEU B 2 84  ? 160.725 232.364 132.877 1.00 202.50 ? 106 LEU B CG  1 
ATOM   2013  C CD1 . LEU B 2 84  ? 160.362 231.638 131.594 1.00 202.50 ? 106 LEU B CD1 1 
ATOM   2014  C CD2 . LEU B 2 84  ? 159.875 233.618 133.019 1.00 202.50 ? 106 LEU B CD2 1 
ATOM   2015  N N   . THR B 2 85  ? 162.550 233.518 136.171 1.00 206.76 ? 107 THR B N   1 
ATOM   2016  C CA  . THR B 2 85  ? 162.655 234.850 136.737 1.00 206.76 ? 107 THR B CA  1 
ATOM   2017  C C   . THR B 2 85  ? 162.834 235.872 135.616 1.00 206.76 ? 107 THR B C   1 
ATOM   2018  O O   . THR B 2 85  ? 162.739 235.550 134.427 1.00 206.76 ? 107 THR B O   1 
ATOM   2019  C CB  . THR B 2 85  ? 163.808 234.908 137.741 1.00 206.76 ? 107 THR B CB  1 
ATOM   2020  O OG1 . THR B 2 85  ? 165.033 234.556 137.084 1.00 206.76 ? 107 THR B OG1 1 
ATOM   2021  C CG2 . THR B 2 85  ? 163.562 233.944 138.891 1.00 206.76 ? 107 THR B CG2 1 
ATOM   2022  N N   . PHE B 2 86  ? 163.098 237.121 135.991 1.00 233.20 ? 108 PHE B N   1 
ATOM   2023  C CA  . PHE B 2 86  ? 163.301 238.170 135.003 1.00 233.20 ? 108 PHE B CA  1 
ATOM   2024  C C   . PHE B 2 86  ? 164.645 237.997 134.307 1.00 233.20 ? 108 PHE B C   1 
ATOM   2025  O O   . PHE B 2 86  ? 165.646 237.631 134.931 1.00 233.20 ? 108 PHE B O   1 
ATOM   2026  C CB  . PHE B 2 86  ? 163.219 239.549 135.661 1.00 233.20 ? 108 PHE B CB  1 
ATOM   2027  C CG  . PHE B 2 86  ? 164.295 239.807 136.680 1.00 233.20 ? 108 PHE B CG  1 
ATOM   2028  C CD1 . PHE B 2 86  ? 164.155 239.361 137.984 1.00 233.20 ? 108 PHE B CD1 1 
ATOM   2029  C CD2 . PHE B 2 86  ? 165.443 240.504 136.336 1.00 233.20 ? 108 PHE B CD2 1 
ATOM   2030  C CE1 . PHE B 2 86  ? 165.141 239.597 138.924 1.00 233.20 ? 108 PHE B CE1 1 
ATOM   2031  C CE2 . PHE B 2 86  ? 166.433 240.743 137.271 1.00 233.20 ? 108 PHE B CE2 1 
ATOM   2032  C CZ  . PHE B 2 86  ? 166.281 240.290 138.567 1.00 233.20 ? 108 PHE B CZ  1 
ATOM   2033  N N   . GLY B 2 87  ? 164.664 238.260 133.003 1.00 250.21 ? 109 GLY B N   1 
ATOM   2034  C CA  . GLY B 2 87  ? 165.875 238.126 132.221 1.00 250.21 ? 109 GLY B CA  1 
ATOM   2035  C C   . GLY B 2 87  ? 166.137 236.745 131.669 1.00 250.21 ? 109 GLY B C   1 
ATOM   2036  O O   . GLY B 2 87  ? 167.294 236.427 131.370 1.00 250.21 ? 109 GLY B O   1 
ATOM   2037  N N   . GLN B 2 88  ? 165.101 235.916 131.522 1.00 254.73 ? 110 GLN B N   1 
ATOM   2038  C CA  . GLN B 2 88  ? 165.236 234.553 131.001 1.00 254.73 ? 110 GLN B CA  1 
ATOM   2039  C C   . GLN B 2 88  ? 166.245 233.742 131.811 1.00 254.73 ? 110 GLN B C   1 
ATOM   2040  O O   . GLN B 2 88  ? 167.028 232.963 131.263 1.00 254.73 ? 110 GLN B O   1 
ATOM   2041  C CB  . GLN B 2 88  ? 165.609 234.561 129.516 1.00 254.73 ? 110 GLN B CB  1 
ATOM   2042  C CG  . GLN B 2 88  ? 164.445 234.836 128.573 1.00 254.73 ? 110 GLN B CG  1 
ATOM   2043  C CD  . GLN B 2 88  ? 164.191 236.317 128.358 1.00 254.73 ? 110 GLN B CD  1 
ATOM   2044  O OE1 . GLN B 2 88  ? 164.260 237.115 129.291 1.00 254.73 ? 110 GLN B OE1 1 
ATOM   2045  N NE2 . GLN B 2 88  ? 163.894 236.690 127.118 1.00 254.73 ? 110 GLN B NE2 1 
ATOM   2046  N N   . LEU B 2 89  ? 166.228 233.927 133.128 1.00 229.39 ? 111 LEU B N   1 
ATOM   2047  C CA  . LEU B 2 89  ? 167.128 233.225 134.033 1.00 229.39 ? 111 LEU B CA  1 
ATOM   2048  C C   . LEU B 2 89  ? 166.400 232.052 134.675 1.00 229.39 ? 111 LEU B C   1 
ATOM   2049  O O   . LEU B 2 89  ? 165.276 232.205 135.164 1.00 229.39 ? 111 LEU B O   1 
ATOM   2050  C CB  . LEU B 2 89  ? 167.666 234.170 135.109 1.00 229.39 ? 111 LEU B CB  1 
ATOM   2051  C CG  . LEU B 2 89  ? 168.580 235.298 134.627 1.00 229.39 ? 111 LEU B CG  1 
ATOM   2052  C CD1 . LEU B 2 89  ? 169.059 236.139 135.799 1.00 229.39 ? 111 LEU B CD1 1 
ATOM   2053  C CD2 . LEU B 2 89  ? 169.759 234.737 133.847 1.00 229.39 ? 111 LEU B CD2 1 
ATOM   2054  N N   . GLU B 2 90  ? 167.041 230.888 134.668 1.00 217.28 ? 112 GLU B N   1 
ATOM   2055  C CA  . GLU B 2 90  ? 166.479 229.677 135.247 1.00 217.28 ? 112 GLU B CA  1 
ATOM   2056  C C   . GLU B 2 90  ? 167.197 229.341 136.548 1.00 217.28 ? 112 GLU B C   1 
ATOM   2057  O O   . GLU B 2 90  ? 168.422 229.463 136.643 1.00 217.28 ? 112 GLU B O   1 
ATOM   2058  C CB  . GLU B 2 90  ? 166.589 228.505 134.269 1.00 217.28 ? 112 GLU B CB  1 
ATOM   2059  C CG  . GLU B 2 90  ? 165.868 227.247 134.720 1.00 217.28 ? 112 GLU B CG  1 
ATOM   2060  C CD  . GLU B 2 90  ? 165.927 226.140 133.686 1.00 217.28 ? 112 GLU B CD  1 
ATOM   2061  O OE1 . GLU B 2 90  ? 166.607 226.325 132.655 1.00 217.28 ? 112 GLU B OE1 1 
ATOM   2062  O OE2 . GLU B 2 90  ? 165.293 225.087 133.903 1.00 217.28 ? 112 GLU B OE2 1 
ATOM   2063  N N   . GLN B 2 91  ? 166.427 228.919 137.548 1.00 215.17 ? 113 GLN B N   1 
ATOM   2064  C CA  . GLN B 2 91  ? 166.956 228.589 138.864 1.00 215.17 ? 113 GLN B CA  1 
ATOM   2065  C C   . GLN B 2 91  ? 166.408 227.240 139.302 1.00 215.17 ? 113 GLN B C   1 
ATOM   2066  O O   . GLN B 2 91  ? 165.203 226.992 139.198 1.00 215.17 ? 113 GLN B O   1 
ATOM   2067  C CB  . GLN B 2 91  ? 166.592 229.669 139.890 1.00 215.17 ? 113 GLN B CB  1 
ATOM   2068  C CG  . GLN B 2 91  ? 167.130 229.410 141.287 1.00 215.17 ? 113 GLN B CG  1 
ATOM   2069  C CD  . GLN B 2 91  ? 166.734 230.493 142.271 1.00 215.17 ? 113 GLN B CD  1 
ATOM   2070  O OE1 . GLN B 2 91  ? 166.009 231.425 141.926 1.00 215.17 ? 113 GLN B OE1 1 
ATOM   2071  N NE2 . GLN B 2 91  ? 167.211 230.375 143.504 1.00 215.17 ? 113 GLN B NE2 1 
ATOM   2072  N N   . ASN B 2 92  ? 167.292 226.374 139.791 1.00 228.74 ? 114 ASN B N   1 
ATOM   2073  C CA  . ASN B 2 92  ? 166.884 225.062 140.268 1.00 228.74 ? 114 ASN B CA  1 
ATOM   2074  C C   . ASN B 2 92  ? 166.191 225.175 141.620 1.00 228.74 ? 114 ASN B C   1 
ATOM   2075  O O   . ASN B 2 92  ? 166.503 226.051 142.432 1.00 228.74 ? 114 ASN B O   1 
ATOM   2076  C CB  . ASN B 2 92  ? 168.091 224.130 140.378 1.00 228.74 ? 114 ASN B CB  1 
ATOM   2077  C CG  . ASN B 2 92  ? 169.114 224.618 141.385 1.00 228.74 ? 114 ASN B CG  1 
ATOM   2078  O OD1 . ASN B 2 92  ? 169.279 225.822 141.586 1.00 228.74 ? 114 ASN B OD1 1 
ATOM   2079  N ND2 . ASN B 2 92  ? 169.806 223.684 142.027 1.00 228.74 ? 114 ASN B ND2 1 
ATOM   2080  N N   . VAL B 2 93  ? 165.238 224.274 141.857 1.00 239.35 ? 115 VAL B N   1 
ATOM   2081  C CA  . VAL B 2 93  ? 164.470 224.284 143.097 1.00 239.35 ? 115 VAL B CA  1 
ATOM   2082  C C   . VAL B 2 93  ? 164.627 222.952 143.822 1.00 239.35 ? 115 VAL B C   1 
ATOM   2083  O O   . VAL B 2 93  ? 165.128 222.905 144.951 1.00 239.35 ? 115 VAL B O   1 
ATOM   2084  C CB  . VAL B 2 93  ? 162.984 224.590 142.831 1.00 239.35 ? 115 VAL B CB  1 
ATOM   2085  C CG1 . VAL B 2 93  ? 162.273 224.912 144.133 1.00 239.35 ? 115 VAL B CG1 1 
ATOM   2086  C CG2 . VAL B 2 93  ? 162.843 225.743 141.847 1.00 239.35 ? 115 VAL B CG2 1 
ATOM   2087  N N   . TYR B 2 94  ? 164.203 221.865 143.181 1.00 255.34 ? 116 TYR B N   1 
ATOM   2088  C CA  . TYR B 2 94  ? 164.230 220.554 143.816 1.00 255.34 ? 116 TYR B CA  1 
ATOM   2089  C C   . TYR B 2 94  ? 164.197 219.479 142.740 1.00 255.34 ? 116 TYR B C   1 
ATOM   2090  O O   . TYR B 2 94  ? 163.844 219.739 141.587 1.00 255.34 ? 116 TYR B O   1 
ATOM   2091  C CB  . TYR B 2 94  ? 163.059 220.383 144.791 1.00 255.34 ? 116 TYR B CB  1 
ATOM   2092  C CG  . TYR B 2 94  ? 163.206 219.214 145.740 1.00 255.34 ? 116 TYR B CG  1 
ATOM   2093  C CD1 . TYR B 2 94  ? 164.084 219.273 146.814 1.00 255.34 ? 116 TYR B CD1 1 
ATOM   2094  C CD2 . TYR B 2 94  ? 162.463 218.054 145.564 1.00 255.34 ? 116 TYR B CD2 1 
ATOM   2095  C CE1 . TYR B 2 94  ? 164.221 218.208 147.684 1.00 255.34 ? 116 TYR B CE1 1 
ATOM   2096  C CE2 . TYR B 2 94  ? 162.593 216.984 146.428 1.00 255.34 ? 116 TYR B CE2 1 
ATOM   2097  C CZ  . TYR B 2 94  ? 163.473 217.066 147.487 1.00 255.34 ? 116 TYR B CZ  1 
ATOM   2098  O OH  . TYR B 2 94  ? 163.606 216.004 148.351 1.00 255.34 ? 116 TYR B OH  1 
ATOM   2099  N N   . GLY B 2 95  ? 164.570 218.269 143.134 1.00 256.21 ? 117 GLY B N   1 
ATOM   2100  C CA  . GLY B 2 95  ? 164.581 217.141 142.217 1.00 256.21 ? 117 GLY B CA  1 
ATOM   2101  C C   . GLY B 2 95  ? 164.249 215.855 142.938 1.00 256.21 ? 117 GLY B C   1 
ATOM   2102  O O   . GLY B 2 95  ? 164.545 215.694 144.126 1.00 256.21 ? 117 GLY B O   1 
ATOM   2103  N N   . ILE B 2 96  ? 163.624 214.931 142.209 1.00 262.22 ? 118 ILE B N   1 
ATOM   2104  C CA  . ILE B 2 96  ? 163.214 213.639 142.738 1.00 262.22 ? 118 ILE B CA  1 
ATOM   2105  C C   . ILE B 2 96  ? 163.720 212.542 141.805 1.00 262.22 ? 118 ILE B C   1 
ATOM   2106  O O   . ILE B 2 96  ? 164.383 212.808 140.803 1.00 262.22 ? 118 ILE B O   1 
ATOM   2107  C CB  . ILE B 2 96  ? 161.686 213.539 142.921 1.00 262.22 ? 118 ILE B CB  1 
ATOM   2108  C CG1 . ILE B 2 96  ? 160.977 213.660 141.571 1.00 262.22 ? 118 ILE B CG1 1 
ATOM   2109  C CG2 . ILE B 2 96  ? 161.192 214.604 143.886 1.00 262.22 ? 118 ILE B CG2 1 
ATOM   2110  C CD1 . ILE B 2 96  ? 159.484 213.442 141.646 1.00 262.22 ? 118 ILE B CD1 1 
ATOM   2111  N N   . THR B 2 97  ? 163.391 211.298 142.147 1.00 252.30 ? 119 THR B N   1 
ATOM   2112  C CA  . THR B 2 97  ? 163.809 210.147 141.358 1.00 252.30 ? 119 THR B CA  1 
ATOM   2113  C C   . THR B 2 97  ? 162.918 208.960 141.694 1.00 252.30 ? 119 THR B C   1 
ATOM   2114  O O   . THR B 2 97  ? 162.400 208.850 142.808 1.00 252.30 ? 119 THR B O   1 
ATOM   2115  C CB  . THR B 2 97  ? 165.279 209.792 141.610 1.00 252.30 ? 119 THR B CB  1 
ATOM   2116  O OG1 . THR B 2 97  ? 165.605 208.583 140.913 1.00 252.30 ? 119 THR B OG1 1 
ATOM   2117  C CG2 . THR B 2 97  ? 165.533 209.599 143.098 1.00 252.30 ? 119 THR B CG2 1 
ATOM   2118  N N   . ILE B 2 98  ? 162.747 208.076 140.712 1.00 238.80 ? 120 ILE B N   1 
ATOM   2119  C CA  . ILE B 2 98  ? 161.947 206.865 140.855 1.00 238.80 ? 120 ILE B CA  1 
ATOM   2120  C C   . ILE B 2 98  ? 162.788 205.685 140.393 1.00 238.80 ? 120 ILE B C   1 
ATOM   2121  O O   . ILE B 2 98  ? 163.252 205.663 139.247 1.00 238.80 ? 120 ILE B O   1 
ATOM   2122  C CB  . ILE B 2 98  ? 160.639 206.943 140.046 1.00 238.80 ? 120 ILE B CB  1 
ATOM   2123  C CG1 . ILE B 2 98  ? 159.871 208.221 140.384 1.00 238.80 ? 120 ILE B CG1 1 
ATOM   2124  C CG2 . ILE B 2 98  ? 159.784 205.715 140.300 1.00 238.80 ? 120 ILE B CG2 1 
ATOM   2125  C CD1 . ILE B 2 98  ? 158.607 208.401 139.581 1.00 238.80 ? 120 ILE B CD1 1 
ATOM   2126  N N   . ILE B 2 99  ? 162.968 204.700 141.271 1.00 245.00 ? 121 ILE B N   1 
ATOM   2127  C CA  . ILE B 2 99  ? 163.878 203.584 141.031 1.00 245.00 ? 121 ILE B CA  1 
ATOM   2128  C C   . ILE B 2 99  ? 163.144 202.275 141.295 1.00 245.00 ? 121 ILE B C   1 
ATOM   2129  O O   . ILE B 2 99  ? 162.557 202.096 142.369 1.00 245.00 ? 121 ILE B O   1 
ATOM   2130  C CB  . ILE B 2 99  ? 165.139 203.668 141.912 1.00 245.00 ? 121 ILE B CB  1 
ATOM   2131  C CG1 . ILE B 2 99  ? 165.874 205.001 141.727 1.00 245.00 ? 121 ILE B CG1 1 
ATOM   2132  C CG2 . ILE B 2 99  ? 166.070 202.500 141.619 1.00 245.00 ? 121 ILE B CG2 1 
ATOM   2133  C CD1 . ILE B 2 99  ? 166.174 205.362 140.290 1.00 245.00 ? 121 ILE B CD1 1 
ATOM   2134  N N   . SER B 2 100 ? 163.182 201.366 140.317 1.00 233.09 ? 122 SER B N   1 
ATOM   2135  C CA  . SER B 2 100 ? 162.876 199.945 140.503 1.00 233.09 ? 122 SER B CA  1 
ATOM   2136  C C   . SER B 2 100 ? 161.460 199.733 141.052 1.00 233.09 ? 122 SER B C   1 
ATOM   2137  O O   . SER B 2 100 ? 161.254 199.288 142.182 1.00 233.09 ? 122 SER B O   1 
ATOM   2138  C CB  . SER B 2 100 ? 163.922 199.287 141.412 1.00 233.09 ? 122 SER B CB  1 
ATOM   2139  O OG  . SER B 2 100 ? 163.420 198.092 141.983 1.00 233.09 ? 122 SER B OG  1 
ATOM   2140  N N   . GLY B 2 101 ? 160.482 200.067 140.213 1.00 184.31 ? 123 GLY B N   1 
ATOM   2141  C CA  . GLY B 2 101 ? 159.094 199.819 140.556 1.00 184.31 ? 123 GLY B CA  1 
ATOM   2142  C C   . GLY B 2 101 ? 158.464 198.677 139.782 1.00 184.31 ? 123 GLY B C   1 
ATOM   2143  O O   . GLY B 2 101 ? 158.209 198.806 138.580 1.00 184.31 ? 123 GLY B O   1 
ATOM   2144  N N   . LEU B 2 102 ? 158.206 197.551 140.458 1.00 136.46 ? 124 LEU B N   1 
ATOM   2145  C CA  . LEU B 2 102 ? 157.587 196.387 139.829 1.00 136.46 ? 124 LEU B CA  1 
ATOM   2146  C C   . LEU B 2 102 ? 157.056 195.423 140.886 1.00 136.46 ? 124 LEU B C   1 
ATOM   2147  O O   . LEU B 2 102 ? 157.775 195.086 141.836 1.00 136.46 ? 124 LEU B O   1 
ATOM   2148  C CB  . LEU B 2 102 ? 158.586 195.676 138.914 1.00 136.46 ? 124 LEU B CB  1 
ATOM   2149  C CG  . LEU B 2 102 ? 158.020 194.620 137.963 1.00 136.46 ? 124 LEU B CG  1 
ATOM   2150  C CD1 . LEU B 2 102 ? 157.139 195.268 136.907 1.00 136.46 ? 124 LEU B CD1 1 
ATOM   2151  C CD2 . LEU B 2 102 ? 159.141 193.828 137.312 1.00 136.46 ? 124 LEU B CD2 1 
ATOM   2152  N N   . PRO B 2 103 ? 155.815 194.958 140.758 1.00 108.46 ? 125 PRO B N   1 
ATOM   2153  C CA  . PRO B 2 103 ? 155.241 194.067 141.773 1.00 108.46 ? 125 PRO B CA  1 
ATOM   2154  C C   . PRO B 2 103 ? 155.604 192.617 141.508 1.00 108.46 ? 125 PRO B C   1 
ATOM   2155  O O   . PRO B 2 103 ? 155.809 192.219 140.351 1.00 108.46 ? 125 PRO B O   1 
ATOM   2156  C CB  . PRO B 2 103 ? 153.732 194.297 141.620 1.00 108.46 ? 125 PRO B CB  1 
ATOM   2157  C CG  . PRO B 2 103 ? 153.569 194.611 140.168 1.00 108.46 ? 125 PRO B CG  1 
ATOM   2158  C CD  . PRO B 2 103 ? 154.826 195.337 139.734 1.00 108.46 ? 125 PRO B CD  1 
ATOM   2159  N N   . PRO B 2 104 ? 155.694 191.791 142.558 1.00 107.33 ? 126 PRO B N   1 
ATOM   2160  C CA  . PRO B 2 104 ? 156.008 190.371 142.360 1.00 107.33 ? 126 PRO B CA  1 
ATOM   2161  C C   . PRO B 2 104 ? 154.772 189.511 142.136 1.00 107.33 ? 126 PRO B C   1 
ATOM   2162  O O   . PRO B 2 104 ? 153.645 190.015 142.137 1.00 107.33 ? 126 PRO B O   1 
ATOM   2163  C CB  . PRO B 2 104 ? 156.720 189.996 143.664 1.00 107.33 ? 126 PRO B CB  1 
ATOM   2164  C CG  . PRO B 2 104 ? 156.072 190.871 144.686 1.00 107.33 ? 126 PRO B CG  1 
ATOM   2165  C CD  . PRO B 2 104 ? 155.683 192.159 143.985 1.00 107.33 ? 126 PRO B CD  1 
ATOM   2166  N N   . GLU B 2 105 ? 154.979 188.208 141.952 1.00 113.00 ? 127 GLU B N   1 
ATOM   2167  C CA  . GLU B 2 105 ? 153.903 187.261 141.702 1.00 113.00 ? 127 GLU B CA  1 
ATOM   2168  C C   . GLU B 2 105 ? 154.009 186.105 142.690 1.00 113.00 ? 127 GLU B C   1 
ATOM   2169  O O   . GLU B 2 105 ? 155.084 185.817 143.224 1.00 113.00 ? 127 GLU B O   1 
ATOM   2170  C CB  . GLU B 2 105 ? 153.945 186.767 140.244 1.00 113.00 ? 127 GLU B CB  1 
ATOM   2171  C CG  . GLU B 2 105 ? 152.719 185.994 139.783 1.00 113.00 ? 127 GLU B CG  1 
ATOM   2172  C CD  . GLU B 2 105 ? 152.849 184.506 140.029 1.00 113.00 ? 127 GLU B CD  1 
ATOM   2173  O OE1 . GLU B 2 105 ? 153.991 184.001 139.998 1.00 113.00 ? 127 GLU B OE1 1 
ATOM   2174  O OE2 . GLU B 2 105 ? 151.818 183.839 140.258 1.00 113.00 ? 127 GLU B OE2 1 
ATOM   2175  N N   . LYS B 2 106 ? 152.874 185.448 142.934 1.00 91.38  ? 128 LYS B N   1 
ATOM   2176  C CA  . LYS B 2 106 ? 152.789 184.453 143.994 1.00 91.38  ? 128 LYS B CA  1 
ATOM   2177  C C   . LYS B 2 106 ? 153.599 183.203 143.647 1.00 91.38  ? 128 LYS B C   1 
ATOM   2178  O O   . LYS B 2 106 ? 153.767 182.867 142.471 1.00 91.38  ? 128 LYS B O   1 
ATOM   2179  C CB  . LYS B 2 106 ? 151.333 184.069 144.255 1.00 91.38  ? 128 LYS B CB  1 
ATOM   2180  C CG  . LYS B 2 106 ? 150.690 183.232 143.165 1.00 91.38  ? 128 LYS B CG  1 
ATOM   2181  C CD  . LYS B 2 106 ? 149.305 182.765 143.580 1.00 91.38  ? 128 LYS B CD  1 
ATOM   2182  C CE  . LYS B 2 106 ? 148.705 181.843 142.534 1.00 91.38  ? 128 LYS B CE  1 
ATOM   2183  N NZ  . LYS B 2 106 ? 147.358 181.363 142.931 1.00 91.38  ? 128 LYS B NZ  1 
ATOM   2184  N N   . PRO B 2 107 ? 154.113 182.493 144.657 1.00 108.00 ? 129 PRO B N   1 
ATOM   2185  C CA  . PRO B 2 107 ? 154.943 181.313 144.379 1.00 108.00 ? 129 PRO B CA  1 
ATOM   2186  C C   . PRO B 2 107 ? 154.131 180.039 144.193 1.00 108.00 ? 129 PRO B C   1 
ATOM   2187  O O   . PRO B 2 107 ? 152.899 180.057 144.266 1.00 108.00 ? 129 PRO B O   1 
ATOM   2188  C CB  . PRO B 2 107 ? 155.834 181.227 145.622 1.00 108.00 ? 129 PRO B CB  1 
ATOM   2189  C CG  . PRO B 2 107 ? 154.970 181.772 146.716 1.00 108.00 ? 129 PRO B CG  1 
ATOM   2190  C CD  . PRO B 2 107 ? 154.075 182.816 146.095 1.00 108.00 ? 129 PRO B CD  1 
ATOM   2191  N N   . LYS B 2 108 ? 154.824 178.929 143.955 1.00 134.91 ? 130 LYS B N   1 
ATOM   2192  C CA  . LYS B 2 108 ? 154.192 177.629 143.762 1.00 134.91 ? 130 LYS B CA  1 
ATOM   2193  C C   . LYS B 2 108 ? 155.221 176.564 144.138 1.00 134.91 ? 130 LYS B C   1 
ATOM   2194  O O   . LYS B 2 108 ? 156.273 176.875 144.706 1.00 134.91 ? 130 LYS B O   1 
ATOM   2195  C CB  . LYS B 2 108 ? 153.665 177.514 142.321 1.00 134.91 ? 130 LYS B CB  1 
ATOM   2196  C CG  . LYS B 2 108 ? 152.764 176.313 142.026 1.00 134.91 ? 130 LYS B CG  1 
ATOM   2197  C CD  . LYS B 2 108 ? 151.502 176.335 142.874 1.00 134.91 ? 130 LYS B CD  1 
ATOM   2198  C CE  . LYS B 2 108 ? 150.619 177.517 142.520 1.00 134.91 ? 130 LYS B CE  1 
ATOM   2199  N NZ  . LYS B 2 108 ? 150.047 177.383 141.154 1.00 134.91 ? 130 LYS B NZ  1 
ATOM   2200  N N   . ASN B 2 109 ? 154.913 175.301 143.833 1.00 197.83 ? 131 ASN B N   1 
ATOM   2201  C CA  . ASN B 2 109 ? 155.795 174.166 144.112 1.00 197.83 ? 131 ASN B CA  1 
ATOM   2202  C C   . ASN B 2 109 ? 156.086 174.058 145.611 1.00 197.83 ? 131 ASN B C   1 
ATOM   2203  O O   . ASN B 2 109 ? 157.232 174.119 146.062 1.00 197.83 ? 131 ASN B O   1 
ATOM   2204  C CB  . ASN B 2 109 ? 157.092 174.263 143.299 1.00 197.83 ? 131 ASN B CB  1 
ATOM   2205  C CG  . ASN B 2 109 ? 157.561 172.915 142.786 1.00 197.83 ? 131 ASN B CG  1 
ATOM   2206  O OD1 . ASN B 2 109 ? 157.402 171.893 143.455 1.00 197.83 ? 131 ASN B OD1 1 
ATOM   2207  N ND2 . ASN B 2 109 ? 158.146 172.906 141.595 1.00 197.83 ? 131 ASN B ND2 1 
ATOM   2208  N N   . LEU B 2 110 ? 155.013 173.892 146.381 1.00 172.81 ? 132 LEU B N   1 
ATOM   2209  C CA  . LEU B 2 110 ? 155.098 173.789 147.833 1.00 172.81 ? 132 LEU B CA  1 
ATOM   2210  C C   . LEU B 2 110 ? 155.356 172.334 148.209 1.00 172.81 ? 132 LEU B C   1 
ATOM   2211  O O   . LEU B 2 110 ? 154.513 171.464 147.967 1.00 172.81 ? 132 LEU B O   1 
ATOM   2212  C CB  . LEU B 2 110 ? 153.819 174.310 148.484 1.00 172.81 ? 132 LEU B CB  1 
ATOM   2213  C CG  . LEU B 2 110 ? 153.744 174.208 150.007 1.00 172.81 ? 132 LEU B CG  1 
ATOM   2214  C CD1 . LEU B 2 110 ? 154.958 174.859 150.650 1.00 172.81 ? 132 LEU B CD1 1 
ATOM   2215  C CD2 . LEU B 2 110 ? 152.459 174.838 150.519 1.00 172.81 ? 132 LEU B CD2 1 
ATOM   2216  N N   . SER B 2 111 ? 156.520 172.072 148.798 1.00 167.66 ? 133 SER B N   1 
ATOM   2217  C CA  . SER B 2 111 ? 156.898 170.731 149.218 1.00 167.66 ? 133 SER B CA  1 
ATOM   2218  C C   . SER B 2 111 ? 157.702 170.818 150.506 1.00 167.66 ? 133 SER B C   1 
ATOM   2219  O O   . SER B 2 111 ? 158.587 171.668 150.638 1.00 167.66 ? 133 SER B O   1 
ATOM   2220  C CB  . SER B 2 111 ? 157.715 170.013 148.136 1.00 167.66 ? 133 SER B CB  1 
ATOM   2221  O OG  . SER B 2 111 ? 159.096 170.307 148.262 1.00 167.66 ? 133 SER B OG  1 
ATOM   2222  N N   . CYS B 2 112 ? 157.391 169.933 151.449 1.00 127.70 ? 134 CYS B N   1 
ATOM   2223  C CA  . CYS B 2 112 ? 158.060 169.891 152.739 1.00 127.70 ? 134 CYS B CA  1 
ATOM   2224  C C   . CYS B 2 112 ? 158.677 168.516 152.960 1.00 127.70 ? 134 CYS B C   1 
ATOM   2225  O O   . CYS B 2 112 ? 158.138 167.497 152.519 1.00 127.70 ? 134 CYS B O   1 
ATOM   2226  C CB  . CYS B 2 112 ? 157.090 170.215 153.881 1.00 127.70 ? 134 CYS B CB  1 
ATOM   2227  S SG  . CYS B 2 112 ? 156.244 171.804 153.713 1.00 127.70 ? 134 CYS B SG  1 
ATOM   2228  N N   . ILE B 2 113 ? 159.813 168.499 153.652 1.00 101.77 ? 135 ILE B N   1 
ATOM   2229  C CA  . ILE B 2 113 ? 160.548 167.274 153.938 1.00 101.77 ? 135 ILE B CA  1 
ATOM   2230  C C   . ILE B 2 113 ? 160.903 167.257 155.418 1.00 101.77 ? 135 ILE B C   1 
ATOM   2231  O O   . ILE B 2 113 ? 161.290 168.284 155.986 1.00 101.77 ? 135 ILE B O   1 
ATOM   2232  C CB  . ILE B 2 113 ? 161.813 167.152 153.058 1.00 101.77 ? 135 ILE B CB  1 
ATOM   2233  C CG1 . ILE B 2 113 ? 162.624 165.910 153.436 1.00 101.77 ? 135 ILE B CG1 1 
ATOM   2234  C CG2 . ILE B 2 113 ? 162.662 168.414 153.151 1.00 101.77 ? 135 ILE B CG2 1 
ATOM   2235  C CD1 . ILE B 2 113 ? 163.845 165.693 152.570 1.00 101.77 ? 135 ILE B CD1 1 
ATOM   2236  N N   . VAL B 2 114 ? 160.759 166.092 156.045 1.00 61.77  ? 136 VAL B N   1 
ATOM   2237  C CA  . VAL B 2 114 ? 161.030 165.915 157.465 1.00 61.77  ? 136 VAL B CA  1 
ATOM   2238  C C   . VAL B 2 114 ? 162.229 164.992 157.621 1.00 61.77  ? 136 VAL B C   1 
ATOM   2239  O O   . VAL B 2 114 ? 162.342 163.982 156.918 1.00 61.77  ? 136 VAL B O   1 
ATOM   2240  C CB  . VAL B 2 114 ? 159.804 165.348 158.212 1.00 61.77  ? 136 VAL B CB  1 
ATOM   2241  C CG1 . VAL B 2 114 ? 160.053 165.329 159.712 1.00 61.77  ? 136 VAL B CG1 1 
ATOM   2242  C CG2 . VAL B 2 114 ? 158.560 166.157 157.883 1.00 61.77  ? 136 VAL B CG2 1 
ATOM   2243  N N   . ASN B 2 115 ? 163.125 165.345 158.536 1.00 84.29  ? 137 ASN B N   1 
ATOM   2244  C CA  . ASN B 2 115 ? 164.294 164.534 158.839 1.00 84.29  ? 137 ASN B CA  1 
ATOM   2245  C C   . ASN B 2 115 ? 164.045 163.697 160.090 1.00 84.29  ? 137 ASN B C   1 
ATOM   2246  O O   . ASN B 2 115 ? 163.038 163.849 160.785 1.00 84.29  ? 137 ASN B O   1 
ATOM   2247  C CB  . ASN B 2 115 ? 165.530 165.419 159.020 1.00 84.29  ? 137 ASN B CB  1 
ATOM   2248  C CG  . ASN B 2 115 ? 165.837 166.247 157.789 1.00 84.29  ? 137 ASN B CG  1 
ATOM   2249  O OD1 . ASN B 2 115 ? 164.971 166.466 156.942 1.00 84.29  ? 137 ASN B OD1 1 
ATOM   2250  N ND2 . ASN B 2 115 ? 167.076 166.714 157.684 1.00 84.29  ? 137 ASN B ND2 1 
ATOM   2251  N N   . GLU B 2 116 ? 164.987 162.800 160.372 1.00 84.28  ? 138 GLU B N   1 
ATOM   2252  C CA  . GLU B 2 116 ? 164.873 161.913 161.526 1.00 84.28  ? 138 GLU B CA  1 
ATOM   2253  C C   . GLU B 2 116 ? 165.125 162.702 162.804 1.00 84.28  ? 138 GLU B C   1 
ATOM   2254  O O   . GLU B 2 116 ? 166.266 163.068 163.103 1.00 84.28  ? 138 GLU B O   1 
ATOM   2255  C CB  . GLU B 2 116 ? 165.853 160.751 161.400 1.00 84.28  ? 138 GLU B CB  1 
ATOM   2256  C CG  . GLU B 2 116 ? 165.668 159.675 162.458 1.00 84.28  ? 138 GLU B CG  1 
ATOM   2257  C CD  . GLU B 2 116 ? 166.736 158.602 162.396 1.00 84.28  ? 138 GLU B CD  1 
ATOM   2258  O OE1 . GLU B 2 116 ? 167.842 158.829 162.931 1.00 84.28  ? 138 GLU B OE1 1 
ATOM   2259  O OE2 . GLU B 2 116 ? 166.469 157.531 161.813 1.00 84.28  ? 138 GLU B OE2 1 
ATOM   2260  N N   . GLY B 2 117 ? 164.063 162.963 163.561 1.00 100.36 ? 139 GLY B N   1 
ATOM   2261  C CA  . GLY B 2 117 ? 164.197 163.668 164.822 1.00 100.36 ? 139 GLY B CA  1 
ATOM   2262  C C   . GLY B 2 117 ? 164.616 165.115 164.697 1.00 100.36 ? 139 GLY B C   1 
ATOM   2263  O O   . GLY B 2 117 ? 165.240 165.653 165.617 1.00 100.36 ? 139 GLY B O   1 
ATOM   2264  N N   . LYS B 2 118 ? 164.292 165.763 163.582 1.00 105.66 ? 140 LYS B N   1 
ATOM   2265  C CA  . LYS B 2 118 ? 164.635 167.159 163.352 1.00 105.66 ? 140 LYS B CA  1 
ATOM   2266  C C   . LYS B 2 118 ? 163.381 167.921 162.939 1.00 105.66 ? 140 LYS B C   1 
ATOM   2267  O O   . LYS B 2 118 ? 162.280 167.366 162.876 1.00 105.66 ? 140 LYS B O   1 
ATOM   2268  C CB  . LYS B 2 118 ? 165.736 167.293 162.292 1.00 105.66 ? 140 LYS B CB  1 
ATOM   2269  C CG  . LYS B 2 118 ? 167.069 166.687 162.702 1.00 105.66 ? 140 LYS B CG  1 
ATOM   2270  C CD  . LYS B 2 118 ? 168.118 166.876 161.619 1.00 105.66 ? 140 LYS B CD  1 
ATOM   2271  C CE  . LYS B 2 118 ? 169.440 166.240 162.015 1.00 105.66 ? 140 LYS B CE  1 
ATOM   2272  N NZ  . LYS B 2 118 ? 170.473 166.403 160.956 1.00 105.66 ? 140 LYS B NZ  1 
ATOM   2273  N N   . LYS B 2 119 ? 163.556 169.208 162.657 1.00 100.39 ? 141 LYS B N   1 
ATOM   2274  C CA  . LYS B 2 119 ? 162.439 170.057 162.276 1.00 100.39 ? 141 LYS B CA  1 
ATOM   2275  C C   . LYS B 2 119 ? 162.105 169.878 160.798 1.00 100.39 ? 141 LYS B C   1 
ATOM   2276  O O   . LYS B 2 119 ? 162.902 169.368 160.006 1.00 100.39 ? 141 LYS B O   1 
ATOM   2277  C CB  . LYS B 2 119 ? 162.753 171.524 162.571 1.00 100.39 ? 141 LYS B CB  1 
ATOM   2278  C CG  . LYS B 2 119 ? 162.719 171.882 164.049 1.00 100.39 ? 141 LYS B CG  1 
ATOM   2279  C CD  . LYS B 2 119 ? 164.087 171.721 164.693 1.00 100.39 ? 141 LYS B CD  1 
ATOM   2280  C CE  . LYS B 2 119 ? 164.058 172.123 166.158 1.00 100.39 ? 141 LYS B CE  1 
ATOM   2281  N NZ  . LYS B 2 119 ? 165.391 171.963 166.803 1.00 100.39 ? 141 LYS B NZ  1 
ATOM   2282  N N   . MET B 2 120 ? 160.902 170.312 160.431 1.00 95.84  ? 142 MET B N   1 
ATOM   2283  C CA  . MET B 2 120 ? 160.408 170.175 159.068 1.00 95.84  ? 142 MET B CA  1 
ATOM   2284  C C   . MET B 2 120 ? 160.852 171.367 158.229 1.00 95.84  ? 142 MET B C   1 
ATOM   2285  O O   . MET B 2 120 ? 160.734 172.517 158.662 1.00 95.84  ? 142 MET B O   1 
ATOM   2286  C CB  . MET B 2 120 ? 158.883 170.059 159.060 1.00 95.84  ? 142 MET B CB  1 
ATOM   2287  C CG  . MET B 2 120 ? 158.279 169.908 157.676 1.00 95.84  ? 142 MET B CG  1 
ATOM   2288  S SD  . MET B 2 120 ? 156.498 169.646 157.733 1.00 95.84  ? 142 MET B SD  1 
ATOM   2289  C CE  . MET B 2 120 ? 155.969 171.118 158.605 1.00 95.84  ? 142 MET B CE  1 
ATOM   2290  N N   . ARG B 2 121 ? 161.360 171.086 157.033 1.00 127.61 ? 143 ARG B N   1 
ATOM   2291  C CA  . ARG B 2 121 ? 161.833 172.110 156.112 1.00 127.61 ? 143 ARG B CA  1 
ATOM   2292  C C   . ARG B 2 121 ? 160.978 172.098 154.852 1.00 127.61 ? 143 ARG B C   1 
ATOM   2293  O O   . ARG B 2 121 ? 160.767 171.040 154.251 1.00 127.61 ? 143 ARG B O   1 
ATOM   2294  C CB  . ARG B 2 121 ? 163.305 171.888 155.756 1.00 127.61 ? 143 ARG B CB  1 
ATOM   2295  C CG  . ARG B 2 121 ? 163.867 172.905 154.777 1.00 127.61 ? 143 ARG B CG  1 
ATOM   2296  C CD  . ARG B 2 121 ? 165.319 172.605 154.446 1.00 127.61 ? 143 ARG B CD  1 
ATOM   2297  N NE  . ARG B 2 121 ? 165.483 171.274 153.870 1.00 127.61 ? 143 ARG B NE  1 
ATOM   2298  C CZ  . ARG B 2 121 ? 166.651 170.759 153.499 1.00 127.61 ? 143 ARG B CZ  1 
ATOM   2299  N NH1 . ARG B 2 121 ? 167.764 171.465 153.643 1.00 127.61 ? 143 ARG B NH1 1 
ATOM   2300  N NH2 . ARG B 2 121 ? 166.707 169.539 152.984 1.00 127.61 ? 143 ARG B NH2 1 
ATOM   2301  N N   . CYS B 2 122 ? 160.493 173.273 154.458 1.00 165.99 ? 144 CYS B N   1 
ATOM   2302  C CA  . CYS B 2 122 ? 159.659 173.429 153.274 1.00 165.99 ? 144 CYS B CA  1 
ATOM   2303  C C   . CYS B 2 122 ? 160.370 174.312 152.259 1.00 165.99 ? 144 CYS B C   1 
ATOM   2304  O O   . CYS B 2 122 ? 161.120 175.220 152.630 1.00 165.99 ? 144 CYS B O   1 
ATOM   2305  C CB  . CYS B 2 122 ? 158.297 174.032 153.631 1.00 165.99 ? 144 CYS B CB  1 
ATOM   2306  S SG  . CYS B 2 122 ? 157.352 173.079 154.841 1.00 165.99 ? 144 CYS B SG  1 
ATOM   2307  N N   . GLU B 2 123 ? 160.131 174.040 150.978 1.00 189.70 ? 145 GLU B N   1 
ATOM   2308  C CA  . GLU B 2 123 ? 160.751 174.784 149.892 1.00 189.70 ? 145 GLU B CA  1 
ATOM   2309  C C   . GLU B 2 123 ? 159.701 175.159 148.855 1.00 189.70 ? 145 GLU B C   1 
ATOM   2310  O O   . GLU B 2 123 ? 158.594 174.614 148.831 1.00 189.70 ? 145 GLU B O   1 
ATOM   2311  C CB  . GLU B 2 123 ? 161.877 173.978 149.226 1.00 189.70 ? 145 GLU B CB  1 
ATOM   2312  C CG  . GLU B 2 123 ? 163.007 173.588 150.165 1.00 189.70 ? 145 GLU B CG  1 
ATOM   2313  C CD  . GLU B 2 123 ? 164.050 172.720 149.491 1.00 189.70 ? 145 GLU B CD  1 
ATOM   2314  O OE1 . GLU B 2 123 ? 164.005 172.589 148.249 1.00 189.70 ? 145 GLU B OE1 1 
ATOM   2315  O OE2 . GLU B 2 123 ? 164.916 172.168 150.202 1.00 189.70 ? 145 GLU B OE2 1 
ATOM   2316  N N   . TRP B 2 124 ? 160.068 176.103 147.994 1.00 182.53 ? 146 TRP B N   1 
ATOM   2317  C CA  . TRP B 2 124 ? 159.209 176.562 146.909 1.00 182.53 ? 146 TRP B CA  1 
ATOM   2318  C C   . TRP B 2 124 ? 160.095 177.205 145.847 1.00 182.53 ? 146 TRP B C   1 
ATOM   2319  O O   . TRP B 2 124 ? 161.322 177.061 145.870 1.00 182.53 ? 146 TRP B O   1 
ATOM   2320  C CB  . TRP B 2 124 ? 158.134 177.524 147.428 1.00 182.53 ? 146 TRP B CB  1 
ATOM   2321  C CG  . TRP B 2 124 ? 158.687 178.713 148.152 1.00 182.53 ? 146 TRP B CG  1 
ATOM   2322  C CD1 . TRP B 2 124 ? 159.083 179.897 147.601 1.00 182.53 ? 146 TRP B CD1 1 
ATOM   2323  C CD2 . TRP B 2 124 ? 158.902 178.835 149.563 1.00 182.53 ? 146 TRP B CD2 1 
ATOM   2324  N NE1 . TRP B 2 124 ? 159.533 180.747 148.582 1.00 182.53 ? 146 TRP B NE1 1 
ATOM   2325  C CE2 . TRP B 2 124 ? 159.432 180.119 149.795 1.00 182.53 ? 146 TRP B CE2 1 
ATOM   2326  C CE3 . TRP B 2 124 ? 158.699 177.983 150.652 1.00 182.53 ? 146 TRP B CE3 1 
ATOM   2327  C CZ2 . TRP B 2 124 ? 159.761 180.571 151.070 1.00 182.53 ? 146 TRP B CZ2 1 
ATOM   2328  C CZ3 . TRP B 2 124 ? 159.026 178.433 151.917 1.00 182.53 ? 146 TRP B CZ3 1 
ATOM   2329  C CH2 . TRP B 2 124 ? 159.552 179.715 152.117 1.00 182.53 ? 146 TRP B CH2 1 
ATOM   2330  N N   . ASP B 2 125 ? 159.473 177.913 144.908 1.00 171.67 ? 147 ASP B N   1 
ATOM   2331  C CA  . ASP B 2 125 ? 160.190 178.628 143.864 1.00 171.67 ? 147 ASP B CA  1 
ATOM   2332  C C   . ASP B 2 125 ? 159.923 180.122 143.985 1.00 171.67 ? 147 ASP B C   1 
ATOM   2333  O O   . ASP B 2 125 ? 158.893 180.545 144.520 1.00 171.67 ? 147 ASP B O   1 
ATOM   2334  C CB  . ASP B 2 125 ? 159.790 178.135 142.465 1.00 171.67 ? 147 ASP B CB  1 
ATOM   2335  C CG  . ASP B 2 125 ? 158.321 178.358 142.163 1.00 171.67 ? 147 ASP B CG  1 
ATOM   2336  O OD1 . ASP B 2 125 ? 157.942 179.503 141.835 1.00 171.67 ? 147 ASP B OD1 1 
ATOM   2337  O OD2 . ASP B 2 125 ? 157.544 177.385 142.245 1.00 171.67 ? 147 ASP B OD2 1 
ATOM   2338  N N   . GLY B 2 126 ? 160.861 180.919 143.479 1.00 180.46 ? 148 GLY B N   1 
ATOM   2339  C CA  . GLY B 2 126 ? 160.737 182.361 143.538 1.00 180.46 ? 148 GLY B CA  1 
ATOM   2340  C C   . GLY B 2 126 ? 159.767 182.922 142.520 1.00 180.46 ? 148 GLY B C   1 
ATOM   2341  O O   . GLY B 2 126 ? 158.989 183.830 142.827 1.00 180.46 ? 148 GLY B O   1 
ATOM   2342  N N   . GLY B 2 127 ? 159.802 182.387 141.302 1.00 183.77 ? 149 GLY B N   1 
ATOM   2343  C CA  . GLY B 2 127 ? 158.921 182.851 140.249 1.00 183.77 ? 149 GLY B CA  1 
ATOM   2344  C C   . GLY B 2 127 ? 159.591 183.820 139.297 1.00 183.77 ? 149 GLY B C   1 
ATOM   2345  O O   . GLY B 2 127 ? 160.811 183.778 139.114 1.00 183.77 ? 149 GLY B O   1 
ATOM   2346  N N   . ARG B 2 128 ? 158.802 184.698 138.686 1.00 155.65 ? 150 ARG B N   1 
ATOM   2347  C CA  . ARG B 2 128 ? 159.347 185.670 137.752 1.00 155.65 ? 150 ARG B CA  1 
ATOM   2348  C C   . ARG B 2 128 ? 160.078 186.783 138.498 1.00 155.65 ? 150 ARG B C   1 
ATOM   2349  O O   . ARG B 2 128 ? 159.826 187.053 139.676 1.00 155.65 ? 150 ARG B O   1 
ATOM   2350  C CB  . ARG B 2 128 ? 158.236 186.262 136.885 1.00 155.65 ? 150 ARG B CB  1 
ATOM   2351  C CG  . ARG B 2 128 ? 157.216 187.082 137.658 1.00 155.65 ? 150 ARG B CG  1 
ATOM   2352  C CD  . ARG B 2 128 ? 156.155 187.653 136.734 1.00 155.65 ? 150 ARG B CD  1 
ATOM   2353  N NE  . ARG B 2 128 ? 155.184 188.471 137.454 1.00 155.65 ? 150 ARG B NE  1 
ATOM   2354  C CZ  . ARG B 2 128 ? 154.138 189.062 136.885 1.00 155.65 ? 150 ARG B CZ  1 
ATOM   2355  N NH1 . ARG B 2 128 ? 153.925 188.926 135.584 1.00 155.65 ? 150 ARG B NH1 1 
ATOM   2356  N NH2 . ARG B 2 128 ? 153.305 189.788 137.617 1.00 155.65 ? 150 ARG B NH2 1 
ATOM   2357  N N   . GLU B 2 129 ? 160.998 187.432 137.790 1.00 143.12 ? 151 GLU B N   1 
ATOM   2358  C CA  . GLU B 2 129 ? 161.762 188.522 138.380 1.00 143.12 ? 151 GLU B CA  1 
ATOM   2359  C C   . GLU B 2 129 ? 160.881 189.750 138.571 1.00 143.12 ? 151 GLU B C   1 
ATOM   2360  O O   . GLU B 2 129 ? 160.070 190.095 137.706 1.00 143.12 ? 151 GLU B O   1 
ATOM   2361  C CB  . GLU B 2 129 ? 162.965 188.865 137.500 1.00 143.12 ? 151 GLU B CB  1 
ATOM   2362  C CG  . GLU B 2 129 ? 163.833 190.005 138.023 1.00 143.12 ? 151 GLU B CG  1 
ATOM   2363  C CD  . GLU B 2 129 ? 164.522 189.685 139.340 1.00 143.12 ? 151 GLU B CD  1 
ATOM   2364  O OE1 . GLU B 2 129 ? 165.051 190.621 139.974 1.00 143.12 ? 151 GLU B OE1 1 
ATOM   2365  O OE2 . GLU B 2 129 ? 164.557 188.499 139.733 1.00 143.12 ? 151 GLU B OE2 1 
ATOM   2366  N N   . THR B 2 130 ? 161.043 190.410 139.717 1.00 146.76 ? 152 THR B N   1 
ATOM   2367  C CA  . THR B 2 130 ? 160.280 191.606 140.041 1.00 146.76 ? 152 THR B CA  1 
ATOM   2368  C C   . THR B 2 130 ? 161.154 192.822 140.309 1.00 146.76 ? 152 THR B C   1 
ATOM   2369  O O   . THR B 2 130 ? 160.616 193.900 140.589 1.00 146.76 ? 152 THR B O   1 
ATOM   2370  C CB  . THR B 2 130 ? 159.382 191.355 141.261 1.00 146.76 ? 152 THR B CB  1 
ATOM   2371  O OG1 . THR B 2 130 ? 158.735 192.576 141.640 1.00 146.76 ? 152 THR B OG1 1 
ATOM   2372  C CG2 . THR B 2 130 ? 160.206 190.839 142.430 1.00 146.76 ? 152 THR B CG2 1 
ATOM   2373  N N   . HIS B 2 131 ? 162.479 192.681 140.244 1.00 167.93 ? 153 HIS B N   1 
ATOM   2374  C CA  . HIS B 2 131 ? 163.428 193.767 140.485 1.00 167.93 ? 153 HIS B CA  1 
ATOM   2375  C C   . HIS B 2 131 ? 163.240 194.414 141.854 1.00 167.93 ? 153 HIS B C   1 
ATOM   2376  O O   . HIS B 2 131 ? 163.658 195.557 142.067 1.00 167.93 ? 153 HIS B O   1 
ATOM   2377  C CB  . HIS B 2 131 ? 163.347 194.833 139.384 1.00 167.93 ? 153 HIS B CB  1 
ATOM   2378  C CG  . HIS B 2 131 ? 163.560 194.294 138.004 1.00 167.93 ? 153 HIS B CG  1 
ATOM   2379  N ND1 . HIS B 2 131 ? 164.812 194.148 137.447 1.00 167.93 ? 153 HIS B ND1 1 
ATOM   2380  C CD2 . HIS B 2 131 ? 162.679 193.869 137.067 1.00 167.93 ? 153 HIS B CD2 1 
ATOM   2381  C CE1 . HIS B 2 131 ? 164.693 193.654 136.227 1.00 167.93 ? 153 HIS B CE1 1 
ATOM   2382  N NE2 . HIS B 2 131 ? 163.410 193.476 135.972 1.00 167.93 ? 153 HIS B NE2 1 
ATOM   2383  N N   . LEU B 2 132 ? 162.618 193.703 142.791 1.00 181.34 ? 154 LEU B N   1 
ATOM   2384  C CA  . LEU B 2 132 ? 162.357 194.240 144.118 1.00 181.34 ? 154 LEU B CA  1 
ATOM   2385  C C   . LEU B 2 132 ? 162.414 193.109 145.133 1.00 181.34 ? 154 LEU B C   1 
ATOM   2386  O O   . LEU B 2 132 ? 162.344 191.928 144.783 1.00 181.34 ? 154 LEU B O   1 
ATOM   2387  C CB  . LEU B 2 132 ? 160.998 194.947 144.183 1.00 181.34 ? 154 LEU B CB  1 
ATOM   2388  C CG  . LEU B 2 132 ? 160.985 196.438 143.842 1.00 181.34 ? 154 LEU B CG  1 
ATOM   2389  C CD1 . LEU B 2 132 ? 159.572 196.992 143.916 1.00 181.34 ? 154 LEU B CD1 1 
ATOM   2390  C CD2 . LEU B 2 132 ? 161.915 197.205 144.769 1.00 181.34 ? 154 LEU B CD2 1 
ATOM   2391  N N   . GLU B 2 133 ? 162.544 193.488 146.400 1.00 182.68 ? 155 GLU B N   1 
ATOM   2392  C CA  . GLU B 2 133 ? 162.572 192.516 147.480 1.00 182.68 ? 155 GLU B CA  1 
ATOM   2393  C C   . GLU B 2 133 ? 161.161 192.055 147.824 1.00 182.68 ? 155 GLU B C   1 
ATOM   2394  O O   . GLU B 2 133 ? 160.199 192.827 147.767 1.00 182.68 ? 155 GLU B O   1 
ATOM   2395  C CB  . GLU B 2 133 ? 163.248 193.107 148.717 1.00 182.68 ? 155 GLU B CB  1 
ATOM   2396  C CG  . GLU B 2 133 ? 162.668 194.438 149.170 1.00 182.68 ? 155 GLU B CG  1 
ATOM   2397  C CD  . GLU B 2 133 ? 161.565 194.276 150.197 1.00 182.68 ? 155 GLU B CD  1 
ATOM   2398  O OE1 . GLU B 2 133 ? 161.454 193.179 150.784 1.00 182.68 ? 155 GLU B OE1 1 
ATOM   2399  O OE2 . GLU B 2 133 ? 160.807 195.244 150.416 1.00 182.68 ? 155 GLU B OE2 1 
ATOM   2400  N N   . THR B 2 134 ? 161.045 190.778 148.181 1.00 173.63 ? 156 THR B N   1 
ATOM   2401  C CA  . THR B 2 134 ? 159.766 190.186 148.556 1.00 173.63 ? 156 THR B CA  1 
ATOM   2402  C C   . THR B 2 134 ? 160.000 189.227 149.712 1.00 173.63 ? 156 THR B C   1 
ATOM   2403  O O   . THR B 2 134 ? 160.732 188.244 149.564 1.00 173.63 ? 156 THR B O   1 
ATOM   2404  C CB  . THR B 2 134 ? 159.120 189.454 147.375 1.00 173.63 ? 156 THR B CB  1 
ATOM   2405  O OG1 . THR B 2 134 ? 158.870 190.384 146.314 1.00 173.63 ? 156 THR B OG1 1 
ATOM   2406  C CG2 . THR B 2 134 ? 157.808 188.813 147.801 1.00 173.63 ? 156 THR B CG2 1 
ATOM   2407  N N   . ASN B 2 135 ? 159.382 189.512 150.854 1.00 154.58 ? 157 ASN B N   1 
ATOM   2408  C CA  . ASN B 2 135 ? 159.535 188.690 152.049 1.00 154.58 ? 157 ASN B CA  1 
ATOM   2409  C C   . ASN B 2 135 ? 158.512 187.561 152.003 1.00 154.58 ? 157 ASN B C   1 
ATOM   2410  O O   . ASN B 2 135 ? 157.315 187.788 152.205 1.00 154.58 ? 157 ASN B O   1 
ATOM   2411  C CB  . ASN B 2 135 ? 159.370 189.536 153.309 1.00 154.58 ? 157 ASN B CB  1 
ATOM   2412  C CG  . ASN B 2 135 ? 160.393 190.651 153.399 1.00 154.58 ? 157 ASN B CG  1 
ATOM   2413  O OD1 . ASN B 2 135 ? 161.487 190.464 153.931 1.00 154.58 ? 157 ASN B OD1 1 
ATOM   2414  N ND2 . ASN B 2 135 ? 160.042 191.820 152.876 1.00 154.58 ? 157 ASN B ND2 1 
ATOM   2415  N N   . PHE B 2 136 ? 158.983 186.346 151.735 1.00 136.27 ? 158 PHE B N   1 
ATOM   2416  C CA  . PHE B 2 136 ? 158.121 185.174 151.684 1.00 136.27 ? 158 PHE B CA  1 
ATOM   2417  C C   . PHE B 2 136 ? 157.988 184.571 153.076 1.00 136.27 ? 158 PHE B C   1 
ATOM   2418  O O   . PHE B 2 136 ? 158.991 184.325 153.753 1.00 136.27 ? 158 PHE B O   1 
ATOM   2419  C CB  . PHE B 2 136 ? 158.676 184.136 150.708 1.00 136.27 ? 158 PHE B CB  1 
ATOM   2420  C CG  . PHE B 2 136 ? 158.700 184.598 149.280 1.00 136.27 ? 158 PHE B CG  1 
ATOM   2421  C CD1 . PHE B 2 136 ? 157.572 184.491 148.484 1.00 136.27 ? 158 PHE B CD1 1 
ATOM   2422  C CD2 . PHE B 2 136 ? 159.852 185.137 148.731 1.00 136.27 ? 158 PHE B CD2 1 
ATOM   2423  C CE1 . PHE B 2 136 ? 157.590 184.914 147.169 1.00 136.27 ? 158 PHE B CE1 1 
ATOM   2424  C CE2 . PHE B 2 136 ? 159.877 185.561 147.416 1.00 136.27 ? 158 PHE B CE2 1 
ATOM   2425  C CZ  . PHE B 2 136 ? 158.744 185.450 146.634 1.00 136.27 ? 158 PHE B CZ  1 
ATOM   2426  N N   . THR B 2 137 ? 156.748 184.336 153.500 1.00 100.54 ? 159 THR B N   1 
ATOM   2427  C CA  . THR B 2 137 ? 156.461 183.759 154.807 1.00 100.54 ? 159 THR B CA  1 
ATOM   2428  C C   . THR B 2 137 ? 155.412 182.668 154.644 1.00 100.54 ? 159 THR B C   1 
ATOM   2429  O O   . THR B 2 137 ? 154.427 182.851 153.922 1.00 100.54 ? 159 THR B O   1 
ATOM   2430  C CB  . THR B 2 137 ? 155.993 184.830 155.801 1.00 100.54 ? 159 THR B CB  1 
ATOM   2431  O OG1 . THR B 2 137 ? 155.709 184.224 157.068 1.00 100.54 ? 159 THR B OG1 1 
ATOM   2432  C CG2 . THR B 2 137 ? 154.757 185.564 155.289 1.00 100.54 ? 159 THR B CG2 1 
ATOM   2433  N N   . LEU B 2 138 ? 155.642 181.528 155.286 1.00 75.85  ? 160 LEU B N   1 
ATOM   2434  C CA  . LEU B 2 138 ? 154.705 180.416 155.261 1.00 75.85  ? 160 LEU B CA  1 
ATOM   2435  C C   . LEU B 2 138 ? 154.014 180.286 156.612 1.00 75.85  ? 160 LEU B C   1 
ATOM   2436  O O   . LEU B 2 138 ? 154.615 180.514 157.665 1.00 75.85  ? 160 LEU B O   1 
ATOM   2437  C CB  . LEU B 2 138 ? 155.411 179.106 154.896 1.00 75.85  ? 160 LEU B CB  1 
ATOM   2438  C CG  . LEU B 2 138 ? 156.195 178.347 155.970 1.00 75.85  ? 160 LEU B CG  1 
ATOM   2439  C CD1 . LEU B 2 138 ? 156.478 176.924 155.515 1.00 75.85  ? 160 LEU B CD1 1 
ATOM   2440  C CD2 . LEU B 2 138 ? 157.489 179.061 156.306 1.00 75.85  ? 160 LEU B CD2 1 
ATOM   2441  N N   . LYS B 2 139 ? 152.734 179.929 156.569 1.00 76.18  ? 161 LYS B N   1 
ATOM   2442  C CA  . LYS B 2 139 ? 151.915 179.780 157.763 1.00 76.18  ? 161 LYS B CA  1 
ATOM   2443  C C   . LYS B 2 139 ? 151.652 178.302 158.013 1.00 76.18  ? 161 LYS B C   1 
ATOM   2444  O O   . LYS B 2 139 ? 151.105 177.610 157.148 1.00 76.18  ? 161 LYS B O   1 
ATOM   2445  C CB  . LYS B 2 139 ? 150.594 180.537 157.619 1.00 76.18  ? 161 LYS B CB  1 
ATOM   2446  C CG  . LYS B 2 139 ? 149.833 180.718 158.922 1.00 76.18  ? 161 LYS B CG  1 
ATOM   2447  C CD  . LYS B 2 139 ? 150.556 181.676 159.856 1.00 76.18  ? 161 LYS B CD  1 
ATOM   2448  C CE  . LYS B 2 139 ? 149.737 181.954 161.106 1.00 76.18  ? 161 LYS B CE  1 
ATOM   2449  N NZ  . LYS B 2 139 ? 149.481 180.716 161.890 1.00 76.18  ? 161 LYS B NZ  1 
ATOM   2450  N N   . SER B 2 140 ? 152.040 177.825 159.193 1.00 47.90  ? 162 SER B N   1 
ATOM   2451  C CA  . SER B 2 140 ? 151.850 176.433 159.581 1.00 47.90  ? 162 SER B CA  1 
ATOM   2452  C C   . SER B 2 140 ? 151.092 176.400 160.897 1.00 47.90  ? 162 SER B C   1 
ATOM   2453  O O   . SER B 2 140 ? 151.529 177.005 161.882 1.00 47.90  ? 162 SER B O   1 
ATOM   2454  C CB  . SER B 2 140 ? 153.192 175.707 159.714 1.00 47.90  ? 162 SER B CB  1 
ATOM   2455  O OG  . SER B 2 140 ? 154.007 176.320 160.697 1.00 47.90  ? 162 SER B OG  1 
ATOM   2456  N N   . GLU B 2 141 ? 149.963 175.697 160.915 1.00 82.10  ? 163 GLU B N   1 
ATOM   2457  C CA  . GLU B 2 141 ? 149.137 175.628 162.111 1.00 82.10  ? 163 GLU B CA  1 
ATOM   2458  C C   . GLU B 2 141 ? 148.287 174.370 162.052 1.00 82.10  ? 163 GLU B C   1 
ATOM   2459  O O   . GLU B 2 141 ? 148.022 173.824 160.978 1.00 82.10  ? 163 GLU B O   1 
ATOM   2460  C CB  . GLU B 2 141 ? 148.255 176.873 162.255 1.00 82.10  ? 163 GLU B CB  1 
ATOM   2461  C CG  . GLU B 2 141 ? 146.942 176.806 161.493 1.00 82.10  ? 163 GLU B CG  1 
ATOM   2462  C CD  . GLU B 2 141 ? 147.133 176.876 159.992 1.00 82.10  ? 163 GLU B CD  1 
ATOM   2463  O OE1 . GLU B 2 141 ? 148.187 177.375 159.547 1.00 82.10  ? 163 GLU B OE1 1 
ATOM   2464  O OE2 . GLU B 2 141 ? 146.227 176.432 159.256 1.00 82.10  ? 163 GLU B OE2 1 
ATOM   2465  N N   . TRP B 2 142 ? 147.863 173.918 163.227 1.00 31.98  ? 164 TRP B N   1 
ATOM   2466  C CA  . TRP B 2 142 ? 147.009 172.748 163.346 1.00 31.98  ? 164 TRP B CA  1 
ATOM   2467  C C   . TRP B 2 142 ? 145.548 173.170 163.200 1.00 31.98  ? 164 TRP B C   1 
ATOM   2468  O O   . TRP B 2 142 ? 145.240 174.300 162.814 1.00 31.98  ? 164 TRP B O   1 
ATOM   2469  C CB  . TRP B 2 142 ? 147.265 172.040 164.674 1.00 31.98  ? 164 TRP B CB  1 
ATOM   2470  C CG  . TRP B 2 142 ? 148.575 171.324 164.731 1.00 31.98  ? 164 TRP B CG  1 
ATOM   2471  C CD1 . TRP B 2 142 ? 149.375 170.997 163.677 1.00 31.98  ? 164 TRP B CD1 1 
ATOM   2472  C CD2 . TRP B 2 142 ? 149.241 170.845 165.905 1.00 31.98  ? 164 TRP B CD2 1 
ATOM   2473  N NE1 . TRP B 2 142 ? 150.499 170.343 164.121 1.00 31.98  ? 164 TRP B NE1 1 
ATOM   2474  C CE2 . TRP B 2 142 ? 150.440 170.237 165.486 1.00 31.98  ? 164 TRP B CE2 1 
ATOM   2475  C CE3 . TRP B 2 142 ? 148.940 170.871 167.270 1.00 31.98  ? 164 TRP B CE3 1 
ATOM   2476  C CZ2 . TRP B 2 142 ? 151.337 169.660 166.381 1.00 31.98  ? 164 TRP B CZ2 1 
ATOM   2477  C CZ3 . TRP B 2 142 ? 149.832 170.298 168.157 1.00 31.98  ? 164 TRP B CZ3 1 
ATOM   2478  C CH2 . TRP B 2 142 ? 151.016 169.701 167.710 1.00 31.98  ? 164 TRP B CH2 1 
ATOM   2479  N N   . ALA B 2 143 ? 144.628 172.255 163.507 1.00 46.46  ? 165 ALA B N   1 
ATOM   2480  C CA  . ALA B 2 143 ? 143.211 172.593 163.447 1.00 46.46  ? 165 ALA B CA  1 
ATOM   2481  C C   . ALA B 2 143 ? 142.808 173.534 164.575 1.00 46.46  ? 165 ALA B C   1 
ATOM   2482  O O   . ALA B 2 143 ? 141.817 174.260 164.449 1.00 46.46  ? 165 ALA B O   1 
ATOM   2483  C CB  . ALA B 2 143 ? 142.363 171.323 163.488 1.00 46.46  ? 165 ALA B CB  1 
ATOM   2484  N N   . THR B 2 144 ? 143.558 173.536 165.680 1.00 33.72  ? 166 THR B N   1 
ATOM   2485  C CA  . THR B 2 144 ? 143.229 174.386 166.814 1.00 33.72  ? 166 THR B CA  1 
ATOM   2486  C C   . THR B 2 144 ? 144.428 175.106 167.414 1.00 33.72  ? 166 THR B C   1 
ATOM   2487  O O   . THR B 2 144 ? 144.243 175.890 168.349 1.00 33.72  ? 166 THR B O   1 
ATOM   2488  C CB  . THR B 2 144 ? 142.538 173.566 167.915 1.00 33.72  ? 166 THR B CB  1 
ATOM   2489  O OG1 . THR B 2 144 ? 142.184 174.426 169.005 1.00 33.72  ? 166 THR B OG1 1 
ATOM   2490  C CG2 . THR B 2 144 ? 143.462 172.470 168.421 1.00 33.72  ? 166 THR B CG2 1 
ATOM   2491  N N   . HIS B 2 145 ? 145.641 174.872 166.920 1.00 44.70  ? 167 HIS B N   1 
ATOM   2492  C CA  . HIS B 2 145 ? 146.834 175.519 167.443 1.00 44.70  ? 167 HIS B CA  1 
ATOM   2493  C C   . HIS B 2 145 ? 147.585 176.200 166.310 1.00 44.70  ? 167 HIS B C   1 
ATOM   2494  O O   . HIS B 2 145 ? 147.692 175.655 165.208 1.00 44.70  ? 167 HIS B O   1 
ATOM   2495  C CB  . HIS B 2 145 ? 147.754 174.517 168.148 1.00 44.70  ? 167 HIS B CB  1 
ATOM   2496  C CG  . HIS B 2 145 ? 149.069 175.097 168.566 1.00 44.70  ? 167 HIS B CG  1 
ATOM   2497  N ND1 . HIS B 2 145 ? 149.183 176.033 169.572 1.00 44.70  ? 167 HIS B ND1 1 
ATOM   2498  C CD2 . HIS B 2 145 ? 150.325 174.878 168.112 1.00 44.70  ? 167 HIS B CD2 1 
ATOM   2499  C CE1 . HIS B 2 145 ? 150.454 176.363 169.721 1.00 44.70  ? 167 HIS B CE1 1 
ATOM   2500  N NE2 . HIS B 2 145 ? 151.168 175.677 168.847 1.00 44.70  ? 167 HIS B NE2 1 
ATOM   2501  N N   . LYS B 2 146 ? 148.106 177.392 166.589 1.00 82.10  ? 168 LYS B N   1 
ATOM   2502  C CA  . LYS B 2 146 ? 148.863 178.173 165.620 1.00 82.10  ? 168 LYS B CA  1 
ATOM   2503  C C   . LYS B 2 146 ? 150.324 178.217 166.042 1.00 82.10  ? 168 LYS B C   1 
ATOM   2504  O O   . LYS B 2 146 ? 150.630 178.489 167.208 1.00 82.10  ? 168 LYS B O   1 
ATOM   2505  C CB  . LYS B 2 146 ? 148.302 179.591 165.497 1.00 82.10  ? 168 LYS B CB  1 
ATOM   2506  C CG  . LYS B 2 146 ? 147.248 179.756 164.413 1.00 82.10  ? 168 LYS B CG  1 
ATOM   2507  C CD  . LYS B 2 146 ? 145.927 179.122 164.818 1.00 82.10  ? 168 LYS B CD  1 
ATOM   2508  C CE  . LYS B 2 146 ? 144.864 179.330 163.752 1.00 82.10  ? 168 LYS B CE  1 
ATOM   2509  N NZ  . LYS B 2 146 ? 143.561 178.725 164.142 1.00 82.10  ? 168 LYS B NZ  1 
ATOM   2510  N N   . PHE B 2 147 ? 151.219 177.949 165.098 1.00 52.53  ? 169 PHE B N   1 
ATOM   2511  C CA  . PHE B 2 147 ? 152.649 177.940 165.355 1.00 52.53  ? 169 PHE B CA  1 
ATOM   2512  C C   . PHE B 2 147 ? 153.273 179.265 164.927 1.00 52.53  ? 169 PHE B C   1 
ATOM   2513  O O   . PHE B 2 147 ? 152.592 180.200 164.499 1.00 52.53  ? 169 PHE B O   1 
ATOM   2514  C CB  . PHE B 2 147 ? 153.316 176.768 164.635 1.00 52.53  ? 169 PHE B CB  1 
ATOM   2515  C CG  . PHE B 2 147 ? 152.950 175.426 165.193 1.00 52.53  ? 169 PHE B CG  1 
ATOM   2516  C CD1 . PHE B 2 147 ? 153.681 174.872 166.228 1.00 52.53  ? 169 PHE B CD1 1 
ATOM   2517  C CD2 . PHE B 2 147 ? 151.878 174.715 164.679 1.00 52.53  ? 169 PHE B CD2 1 
ATOM   2518  C CE1 . PHE B 2 147 ? 153.351 173.636 166.743 1.00 52.53  ? 169 PHE B CE1 1 
ATOM   2519  C CE2 . PHE B 2 147 ? 151.543 173.477 165.191 1.00 52.53  ? 169 PHE B CE2 1 
ATOM   2520  C CZ  . PHE B 2 147 ? 152.282 172.938 166.224 1.00 52.53  ? 169 PHE B CZ  1 
ATOM   2521  N N   . ALA B 2 148 ? 154.595 179.340 165.046 1.00 72.80  ? 170 ALA B N   1 
ATOM   2522  C CA  . ALA B 2 148 ? 155.338 180.520 164.636 1.00 72.80  ? 170 ALA B CA  1 
ATOM   2523  C C   . ALA B 2 148 ? 155.520 180.528 163.119 1.00 72.80  ? 170 ALA B C   1 
ATOM   2524  O O   . ALA B 2 148 ? 155.117 179.600 162.411 1.00 72.80  ? 170 ALA B O   1 
ATOM   2525  C CB  . ALA B 2 148 ? 156.684 180.576 165.354 1.00 72.80  ? 170 ALA B CB  1 
ATOM   2526  N N   . ASP B 2 149 ? 156.138 181.589 162.609 1.00 86.13  ? 171 ASP B N   1 
ATOM   2527  C CA  . ASP B 2 149 ? 156.351 181.771 161.182 1.00 86.13  ? 171 ASP B CA  1 
ATOM   2528  C C   . ASP B 2 149 ? 157.842 181.857 160.881 1.00 86.13  ? 171 ASP B C   1 
ATOM   2529  O O   . ASP B 2 149 ? 158.670 182.080 161.766 1.00 86.13  ? 171 ASP B O   1 
ATOM   2530  C CB  . ASP B 2 149 ? 155.636 183.032 160.675 1.00 86.13  ? 171 ASP B CB  1 
ATOM   2531  C CG  . ASP B 2 149 ? 154.162 183.053 161.036 1.00 86.13  ? 171 ASP B CG  1 
ATOM   2532  O OD1 . ASP B 2 149 ? 153.578 181.964 161.221 1.00 86.13  ? 171 ASP B OD1 1 
ATOM   2533  O OD2 . ASP B 2 149 ? 153.588 184.158 161.131 1.00 86.13  ? 171 ASP B OD2 1 
ATOM   2534  N N   . CYS B 2 150 ? 158.179 181.672 159.608 1.00 110.04 ? 172 CYS B N   1 
ATOM   2535  C CA  . CYS B 2 150 ? 159.541 181.827 159.115 1.00 110.04 ? 172 CYS B CA  1 
ATOM   2536  C C   . CYS B 2 150 ? 159.632 183.038 158.199 1.00 110.04 ? 172 CYS B C   1 
ATOM   2537  O O   . CYS B 2 150 ? 158.714 183.307 157.417 1.00 110.04 ? 172 CYS B O   1 
ATOM   2538  C CB  . CYS B 2 150 ? 160.007 180.584 158.352 1.00 110.04 ? 172 CYS B CB  1 
ATOM   2539  S SG  . CYS B 2 150 ? 161.400 180.901 157.238 1.00 110.04 ? 172 CYS B SG  1 
ATOM   2540  N N   . LYS B 2 151 ? 160.744 183.760 158.301 1.00 129.22 ? 173 LYS B N   1 
ATOM   2541  C CA  . LYS B 2 151 ? 161.011 184.922 157.467 1.00 129.22 ? 173 LYS B CA  1 
ATOM   2542  C C   . LYS B 2 151 ? 162.011 184.527 156.391 1.00 129.22 ? 173 LYS B C   1 
ATOM   2543  O O   . LYS B 2 151 ? 163.012 183.865 156.685 1.00 129.22 ? 173 LYS B O   1 
ATOM   2544  C CB  . LYS B 2 151 ? 161.551 186.090 158.298 1.00 129.22 ? 173 LYS B CB  1 
ATOM   2545  C CG  . LYS B 2 151 ? 160.801 186.413 159.606 1.00 129.22 ? 173 LYS B CG  1 
ATOM   2546  C CD  . LYS B 2 151 ? 159.284 186.197 159.560 1.00 129.22 ? 173 LYS B CD  1 
ATOM   2547  C CE  . LYS B 2 151 ? 158.585 187.140 158.588 1.00 129.22 ? 173 LYS B CE  1 
ATOM   2548  N NZ  . LYS B 2 151 ? 157.136 186.812 158.456 1.00 129.22 ? 173 LYS B NZ  1 
ATOM   2549  N N   . ALA B 2 152 ? 161.739 184.926 155.152 1.00 140.17 ? 174 ALA B N   1 
ATOM   2550  C CA  . ALA B 2 152 ? 162.613 184.581 154.036 1.00 140.17 ? 174 ALA B CA  1 
ATOM   2551  C C   . ALA B 2 152 ? 163.964 185.264 154.201 1.00 140.17 ? 174 ALA B C   1 
ATOM   2552  O O   . ALA B 2 152 ? 164.046 186.496 154.243 1.00 140.17 ? 174 ALA B O   1 
ATOM   2553  C CB  . ALA B 2 152 ? 161.969 184.979 152.711 1.00 140.17 ? 174 ALA B CB  1 
ATOM   2554  N N   . LYS B 2 153 ? 165.022 184.464 154.296 1.00 162.25 ? 175 LYS B N   1 
ATOM   2555  C CA  . LYS B 2 153 ? 166.364 185.002 154.431 1.00 162.25 ? 175 LYS B CA  1 
ATOM   2556  C C   . LYS B 2 153 ? 166.879 185.503 153.084 1.00 162.25 ? 175 LYS B C   1 
ATOM   2557  O O   . LYS B 2 153 ? 166.366 185.149 152.019 1.00 162.25 ? 175 LYS B O   1 
ATOM   2558  C CB  . LYS B 2 153 ? 167.311 183.946 154.999 1.00 162.25 ? 175 LYS B CB  1 
ATOM   2559  C CG  . LYS B 2 153 ? 166.824 183.310 156.290 1.00 162.25 ? 175 LYS B CG  1 
ATOM   2560  C CD  . LYS B 2 153 ? 166.581 184.359 157.363 1.00 162.25 ? 175 LYS B CD  1 
ATOM   2561  C CE  . LYS B 2 153 ? 166.070 183.726 158.646 1.00 162.25 ? 175 LYS B CE  1 
ATOM   2562  N NZ  . LYS B 2 153 ? 165.836 184.739 159.712 1.00 162.25 ? 175 LYS B NZ  1 
ATOM   2563  N N   . ARG B 2 154 ? 167.913 186.343 153.145 1.00 186.59 ? 176 ARG B N   1 
ATOM   2564  C CA  . ARG B 2 154 ? 168.480 186.926 151.936 1.00 186.59 ? 176 ARG B CA  1 
ATOM   2565  C C   . ARG B 2 154 ? 169.391 185.963 151.187 1.00 186.59 ? 176 ARG B C   1 
ATOM   2566  O O   . ARG B 2 154 ? 169.566 186.117 149.974 1.00 186.59 ? 176 ARG B O   1 
ATOM   2567  C CB  . ARG B 2 154 ? 169.252 188.202 152.280 1.00 186.59 ? 176 ARG B CB  1 
ATOM   2568  C CG  . ARG B 2 154 ? 168.398 189.285 152.916 1.00 186.59 ? 176 ARG B CG  1 
ATOM   2569  C CD  . ARG B 2 154 ? 169.190 190.563 153.127 1.00 186.59 ? 176 ARG B CD  1 
ATOM   2570  N NE  . ARG B 2 154 ? 168.371 191.621 153.713 1.00 186.59 ? 176 ARG B NE  1 
ATOM   2571  C CZ  . ARG B 2 154 ? 168.806 192.851 153.962 1.00 186.59 ? 176 ARG B CZ  1 
ATOM   2572  N NH1 . ARG B 2 154 ? 170.057 193.186 153.675 1.00 186.59 ? 176 ARG B NH1 1 
ATOM   2573  N NH2 . ARG B 2 154 ? 167.990 193.749 154.497 1.00 186.59 ? 176 ARG B NH2 1 
ATOM   2574  N N   . ASP B 2 155 ? 169.976 184.982 151.877 1.00 198.02 ? 177 ASP B N   1 
ATOM   2575  C CA  . ASP B 2 155 ? 170.825 184.008 151.199 1.00 198.02 ? 177 ASP B CA  1 
ATOM   2576  C C   . ASP B 2 155 ? 169.998 183.093 150.304 1.00 198.02 ? 177 ASP B C   1 
ATOM   2577  O O   . ASP B 2 155 ? 170.351 182.857 149.143 1.00 198.02 ? 177 ASP B O   1 
ATOM   2578  C CB  . ASP B 2 155 ? 171.612 183.193 152.226 1.00 198.02 ? 177 ASP B CB  1 
ATOM   2579  C CG  . ASP B 2 155 ? 172.917 182.657 151.670 1.00 198.02 ? 177 ASP B CG  1 
ATOM   2580  O OD1 . ASP B 2 155 ? 173.014 182.481 150.437 1.00 198.02 ? 177 ASP B OD1 1 
ATOM   2581  O OD2 . ASP B 2 155 ? 173.847 182.411 152.467 1.00 198.02 ? 177 ASP B OD2 1 
ATOM   2582  N N   . THR B 2 156 ? 168.893 182.570 150.828 1.00 212.48 ? 178 THR B N   1 
ATOM   2583  C CA  . THR B 2 156 ? 167.998 181.718 150.057 1.00 212.48 ? 178 THR B CA  1 
ATOM   2584  C C   . THR B 2 156 ? 166.548 181.985 150.451 1.00 212.48 ? 178 THR B C   1 
ATOM   2585  O O   . THR B 2 156 ? 166.122 181.637 151.559 1.00 212.48 ? 178 THR B O   1 
ATOM   2586  C CB  . THR B 2 156 ? 168.364 180.240 150.242 1.00 212.48 ? 178 THR B CB  1 
ATOM   2587  O OG1 . THR B 2 156 ? 167.333 179.411 149.691 1.00 212.48 ? 178 THR B OG1 1 
ATOM   2588  C CG2 . THR B 2 156 ? 168.593 179.897 151.715 1.00 212.48 ? 178 THR B CG2 1 
ATOM   2589  N N   . PRO B 2 157 ? 165.763 182.615 149.576 1.00 208.83 ? 179 PRO B N   1 
ATOM   2590  C CA  . PRO B 2 157 ? 164.369 182.926 149.904 1.00 208.83 ? 179 PRO B CA  1 
ATOM   2591  C C   . PRO B 2 157 ? 163.393 181.780 149.685 1.00 208.83 ? 179 PRO B C   1 
ATOM   2592  O O   . PRO B 2 157 ? 162.184 182.024 149.658 1.00 208.83 ? 179 PRO B O   1 
ATOM   2593  C CB  . PRO B 2 157 ? 164.059 184.089 148.950 1.00 208.83 ? 179 PRO B CB  1 
ATOM   2594  C CG  . PRO B 2 157 ? 164.890 183.795 147.750 1.00 208.83 ? 179 PRO B CG  1 
ATOM   2595  C CD  . PRO B 2 157 ? 166.153 183.137 148.254 1.00 208.83 ? 179 PRO B CD  1 
ATOM   2596  N N   . THR B 2 158 ? 163.872 180.550 149.524 1.00 202.20 ? 180 THR B N   1 
ATOM   2597  C CA  . THR B 2 158 ? 163.018 179.397 149.269 1.00 202.20 ? 180 THR B CA  1 
ATOM   2598  C C   . THR B 2 158 ? 163.337 178.264 150.234 1.00 202.20 ? 180 THR B C   1 
ATOM   2599  O O   . THR B 2 158 ? 163.389 177.092 149.850 1.00 202.20 ? 180 THR B O   1 
ATOM   2600  C CB  . THR B 2 158 ? 163.159 178.920 147.825 1.00 202.20 ? 180 THR B CB  1 
ATOM   2601  O OG1 . THR B 2 158 ? 164.544 178.714 147.523 1.00 202.20 ? 180 THR B OG1 1 
ATOM   2602  C CG2 . THR B 2 158 ? 162.583 179.948 146.861 1.00 202.20 ? 180 THR B CG2 1 
ATOM   2603  N N   . SER B 2 159 ? 163.553 178.595 151.506 1.00 202.13 ? 181 SER B N   1 
ATOM   2604  C CA  . SER B 2 159 ? 163.884 177.590 152.507 1.00 202.13 ? 181 SER B CA  1 
ATOM   2605  C C   . SER B 2 159 ? 163.525 178.119 153.888 1.00 202.13 ? 181 SER B C   1 
ATOM   2606  O O   . SER B 2 159 ? 163.728 179.300 154.177 1.00 202.13 ? 181 SER B O   1 
ATOM   2607  C CB  . SER B 2 159 ? 165.369 177.215 152.448 1.00 202.13 ? 181 SER B CB  1 
ATOM   2608  O OG  . SER B 2 159 ? 165.614 176.263 151.427 1.00 202.13 ? 181 SER B OG  1 
ATOM   2609  N N   . CYS B 2 160 ? 162.997 177.235 154.734 1.00 151.79 ? 182 CYS B N   1 
ATOM   2610  C CA  . CYS B 2 160 ? 162.621 177.584 156.097 1.00 151.79 ? 182 CYS B CA  1 
ATOM   2611  C C   . CYS B 2 160 ? 162.758 176.369 156.999 1.00 151.79 ? 182 CYS B C   1 
ATOM   2612  O O   . CYS B 2 160 ? 162.422 175.250 156.603 1.00 151.79 ? 182 CYS B O   1 
ATOM   2613  C CB  . CYS B 2 160 ? 161.187 178.123 156.177 1.00 151.79 ? 182 CYS B CB  1 
ATOM   2614  S SG  . CYS B 2 160 ? 160.978 179.807 155.581 1.00 151.79 ? 182 CYS B SG  1 
ATOM   2615  N N   . THR B 2 161 ? 163.256 176.604 158.211 1.00 119.02 ? 183 THR B N   1 
ATOM   2616  C CA  . THR B 2 161 ? 163.328 175.592 159.257 1.00 119.02 ? 183 THR B CA  1 
ATOM   2617  C C   . THR B 2 161 ? 162.520 176.086 160.447 1.00 119.02 ? 183 THR B C   1 
ATOM   2618  O O   . THR B 2 161 ? 162.836 177.134 161.022 1.00 119.02 ? 183 THR B O   1 
ATOM   2619  C CB  . THR B 2 161 ? 164.775 175.316 159.670 1.00 119.02 ? 183 THR B CB  1 
ATOM   2620  O OG1 . THR B 2 161 ? 165.226 176.346 160.559 1.00 119.02 ? 183 THR B OG1 1 
ATOM   2621  C CG2 . THR B 2 161 ? 165.680 175.275 158.452 1.00 119.02 ? 183 THR B CG2 1 
ATOM   2622  N N   . VAL B 2 162 ? 161.483 175.335 160.812 1.00 84.80  ? 184 VAL B N   1 
ATOM   2623  C CA  . VAL B 2 162 ? 160.604 175.717 161.911 1.00 84.80  ? 184 VAL B CA  1 
ATOM   2624  C C   . VAL B 2 162 ? 161.360 175.603 163.228 1.00 84.80  ? 184 VAL B C   1 
ATOM   2625  O O   . VAL B 2 162 ? 162.444 175.014 163.287 1.00 84.80  ? 184 VAL B O   1 
ATOM   2626  C CB  . VAL B 2 162 ? 159.326 174.859 161.929 1.00 84.80  ? 184 VAL B CB  1 
ATOM   2627  C CG1 . VAL B 2 162 ? 158.389 175.288 160.812 1.00 84.80  ? 184 VAL B CG1 1 
ATOM   2628  C CG2 . VAL B 2 162 ? 159.672 173.383 161.808 1.00 84.80  ? 184 VAL B CG2 1 
ATOM   2629  N N   . ASP B 2 163 ? 160.793 176.170 164.293 1.00 72.20  ? 185 ASP B N   1 
ATOM   2630  C CA  . ASP B 2 163 ? 161.438 176.201 165.599 1.00 72.20  ? 185 ASP B CA  1 
ATOM   2631  C C   . ASP B 2 163 ? 160.818 175.227 166.595 1.00 72.20  ? 185 ASP B C   1 
ATOM   2632  O O   . ASP B 2 163 ? 161.270 175.161 167.743 1.00 72.20  ? 185 ASP B O   1 
ATOM   2633  C CB  . ASP B 2 163 ? 161.414 177.626 166.159 1.00 72.20  ? 185 ASP B CB  1 
ATOM   2634  C CG  . ASP B 2 163 ? 160.007 178.205 166.252 1.00 72.20  ? 185 ASP B CG  1 
ATOM   2635  O OD1 . ASP B 2 163 ? 159.853 179.414 165.979 1.00 72.20  ? 185 ASP B OD1 1 
ATOM   2636  O OD2 . ASP B 2 163 ? 159.058 177.468 166.591 1.00 72.20  ? 185 ASP B OD2 1 
ATOM   2637  N N   . TYR B 2 164 ? 159.803 174.471 166.189 1.00 49.54  ? 186 TYR B N   1 
ATOM   2638  C CA  . TYR B 2 164 ? 159.138 173.521 167.067 1.00 49.54  ? 186 TYR B CA  1 
ATOM   2639  C C   . TYR B 2 164 ? 159.425 172.099 166.609 1.00 49.54  ? 186 TYR B C   1 
ATOM   2640  O O   . TYR B 2 164 ? 159.678 171.847 165.427 1.00 49.54  ? 186 TYR B O   1 
ATOM   2641  C CB  . TYR B 2 164 ? 157.622 173.763 167.109 1.00 49.54  ? 186 TYR B CB  1 
ATOM   2642  C CG  . TYR B 2 164 ? 156.940 173.691 165.761 1.00 49.54  ? 186 TYR B CG  1 
ATOM   2643  C CD1 . TYR B 2 164 ? 156.850 174.813 164.948 1.00 49.54  ? 186 TYR B CD1 1 
ATOM   2644  C CD2 . TYR B 2 164 ? 156.379 172.506 165.305 1.00 49.54  ? 186 TYR B CD2 1 
ATOM   2645  C CE1 . TYR B 2 164 ? 156.226 174.756 163.719 1.00 49.54  ? 186 TYR B CE1 1 
ATOM   2646  C CE2 . TYR B 2 164 ? 155.752 172.439 164.075 1.00 49.54  ? 186 TYR B CE2 1 
ATOM   2647  C CZ  . TYR B 2 164 ? 155.679 173.567 163.286 1.00 49.54  ? 186 TYR B CZ  1 
ATOM   2648  O OH  . TYR B 2 164 ? 155.056 173.505 162.060 1.00 49.54  ? 186 TYR B OH  1 
ATOM   2649  N N   . SER B 2 165 ? 159.380 171.170 167.560 1.00 53.68  ? 187 SER B N   1 
ATOM   2650  C CA  . SER B 2 165 ? 159.668 169.774 167.264 1.00 53.68  ? 187 SER B CA  1 
ATOM   2651  C C   . SER B 2 165 ? 158.565 169.167 166.406 1.00 53.68  ? 187 SER B C   1 
ATOM   2652  O O   . SER B 2 165 ? 157.392 169.532 166.521 1.00 53.68  ? 187 SER B O   1 
ATOM   2653  C CB  . SER B 2 165 ? 159.822 168.979 168.559 1.00 53.68  ? 187 SER B CB  1 
ATOM   2654  O OG  . SER B 2 165 ? 158.570 168.794 169.196 1.00 53.68  ? 187 SER B OG  1 
ATOM   2655  N N   . THR B 2 166 ? 158.951 168.232 165.542 1.00 44.55  ? 188 THR B N   1 
ATOM   2656  C CA  . THR B 2 166 ? 157.999 167.587 164.648 1.00 44.55  ? 188 THR B CA  1 
ATOM   2657  C C   . THR B 2 166 ? 157.133 166.606 165.429 1.00 44.55  ? 188 THR B C   1 
ATOM   2658  O O   . THR B 2 166 ? 157.644 165.648 166.019 1.00 44.55  ? 188 THR B O   1 
ATOM   2659  C CB  . THR B 2 166 ? 158.734 166.869 163.520 1.00 44.55  ? 188 THR B CB  1 
ATOM   2660  O OG1 . THR B 2 166 ? 159.574 167.801 162.827 1.00 44.55  ? 188 THR B OG1 1 
ATOM   2661  C CG2 . THR B 2 166 ? 157.741 166.265 162.540 1.00 44.55  ? 188 THR B CG2 1 
ATOM   2662  N N   . VAL B 2 167 ? 155.826 166.843 165.431 1.00 45.57  ? 189 VAL B N   1 
ATOM   2663  C CA  . VAL B 2 167 ? 154.865 165.975 166.102 1.00 45.57  ? 189 VAL B CA  1 
ATOM   2664  C C   . VAL B 2 167 ? 154.258 165.062 165.045 1.00 45.57  ? 189 VAL B C   1 
ATOM   2665  O O   . VAL B 2 167 ? 153.503 165.514 164.178 1.00 45.57  ? 189 VAL B O   1 
ATOM   2666  C CB  . VAL B 2 167 ? 153.786 166.784 166.832 1.00 45.57  ? 189 VAL B CB  1 
ATOM   2667  C CG1 . VAL B 2 167 ? 152.860 165.856 167.601 1.00 45.57  ? 189 VAL B CG1 1 
ATOM   2668  C CG2 . VAL B 2 167 ? 154.428 167.800 167.764 1.00 45.57  ? 189 VAL B CG2 1 
ATOM   2669  N N   . TYR B 2 168 ? 154.586 163.776 165.116 1.00 82.10  ? 190 TYR B N   1 
ATOM   2670  C CA  . TYR B 2 168 ? 154.137 162.829 164.108 1.00 82.10  ? 190 TYR B CA  1 
ATOM   2671  C C   . TYR B 2 168 ? 152.648 162.531 164.262 1.00 82.10  ? 190 TYR B C   1 
ATOM   2672  O O   . TYR B 2 168 ? 152.035 162.798 165.300 1.00 82.10  ? 190 TYR B O   1 
ATOM   2673  C CB  . TYR B 2 168 ? 154.941 161.532 164.198 1.00 82.10  ? 190 TYR B CB  1 
ATOM   2674  C CG  . TYR B 2 168 ? 156.426 161.718 163.982 1.00 82.10  ? 190 TYR B CG  1 
ATOM   2675  C CD1 . TYR B 2 168 ? 156.978 161.629 162.712 1.00 82.10  ? 190 TYR B CD1 1 
ATOM   2676  C CD2 . TYR B 2 168 ? 157.275 161.984 165.048 1.00 82.10  ? 190 TYR B CD2 1 
ATOM   2677  C CE1 . TYR B 2 168 ? 158.333 161.798 162.509 1.00 82.10  ? 190 TYR B CE1 1 
ATOM   2678  C CE2 . TYR B 2 168 ? 158.631 162.155 164.854 1.00 82.10  ? 190 TYR B CE2 1 
ATOM   2679  C CZ  . TYR B 2 168 ? 159.155 162.061 163.583 1.00 82.10  ? 190 TYR B CZ  1 
ATOM   2680  O OH  . TYR B 2 168 ? 160.505 162.230 163.385 1.00 82.10  ? 190 TYR B OH  1 
ATOM   2681  N N   . PHE B 2 169 ? 152.070 161.975 163.196 1.00 40.73  ? 191 PHE B N   1 
ATOM   2682  C CA  . PHE B 2 169 ? 150.675 161.530 163.181 1.00 40.73  ? 191 PHE B CA  1 
ATOM   2683  C C   . PHE B 2 169 ? 149.710 162.685 163.445 1.00 40.73  ? 191 PHE B C   1 
ATOM   2684  O O   . PHE B 2 169 ? 148.668 162.514 164.081 1.00 40.73  ? 191 PHE B O   1 
ATOM   2685  C CB  . PHE B 2 169 ? 150.449 160.392 164.179 1.00 40.73  ? 191 PHE B CB  1 
ATOM   2686  C CG  . PHE B 2 169 ? 151.517 159.337 164.146 1.00 40.73  ? 191 PHE B CG  1 
ATOM   2687  C CD1 . PHE B 2 169 ? 151.641 158.495 163.055 1.00 40.73  ? 191 PHE B CD1 1 
ATOM   2688  C CD2 . PHE B 2 169 ? 152.394 159.187 165.206 1.00 40.73  ? 191 PHE B CD2 1 
ATOM   2689  C CE1 . PHE B 2 169 ? 152.624 157.524 163.019 1.00 40.73  ? 191 PHE B CE1 1 
ATOM   2690  C CE2 . PHE B 2 169 ? 153.378 158.216 165.177 1.00 40.73  ? 191 PHE B CE2 1 
ATOM   2691  C CZ  . PHE B 2 169 ? 153.492 157.384 164.082 1.00 40.73  ? 191 PHE B CZ  1 
ATOM   2692  N N   . VAL B 2 170 ? 150.056 163.872 162.950 1.00 49.64  ? 192 VAL B N   1 
ATOM   2693  C CA  . VAL B 2 170 ? 149.236 165.068 163.119 1.00 49.64  ? 192 VAL B CA  1 
ATOM   2694  C C   . VAL B 2 170 ? 149.171 165.782 161.775 1.00 49.64  ? 192 VAL B C   1 
ATOM   2695  O O   . VAL B 2 170 ? 150.157 166.391 161.346 1.00 49.64  ? 192 VAL B O   1 
ATOM   2696  C CB  . VAL B 2 170 ? 149.785 166.010 164.201 1.00 49.64  ? 192 VAL B CB  1 
ATOM   2697  C CG1 . VAL B 2 170 ? 149.007 167.313 164.208 1.00 49.64  ? 192 VAL B CG1 1 
ATOM   2698  C CG2 . VAL B 2 170 ? 149.727 165.347 165.568 1.00 49.64  ? 192 VAL B CG2 1 
ATOM   2699  N N   . ASN B 2 171 ? 148.017 165.715 161.113 1.00 36.80  ? 193 ASN B N   1 
ATOM   2700  C CA  . ASN B 2 171 ? 147.841 166.369 159.819 1.00 36.80  ? 193 ASN B CA  1 
ATOM   2701  C C   . ASN B 2 171 ? 147.850 167.881 160.007 1.00 36.80  ? 193 ASN B C   1 
ATOM   2702  O O   . ASN B 2 171 ? 146.946 168.443 160.632 1.00 36.80  ? 193 ASN B O   1 
ATOM   2703  C CB  . ASN B 2 171 ? 146.544 165.907 159.163 1.00 36.80  ? 193 ASN B CB  1 
ATOM   2704  C CG  . ASN B 2 171 ? 146.722 164.640 158.349 1.00 36.80  ? 193 ASN B CG  1 
ATOM   2705  O OD1 . ASN B 2 171 ? 147.838 164.285 157.970 1.00 36.80  ? 193 ASN B OD1 1 
ATOM   2706  N ND2 . ASN B 2 171 ? 145.620 163.955 158.070 1.00 36.80  ? 193 ASN B ND2 1 
ATOM   2707  N N   . ILE B 2 172 ? 148.871 168.540 159.465 1.00 24.57  ? 194 ILE B N   1 
ATOM   2708  C CA  . ILE B 2 172 ? 149.044 169.982 159.584 1.00 24.57  ? 194 ILE B CA  1 
ATOM   2709  C C   . ILE B 2 172 ? 148.835 170.614 158.214 1.00 24.57  ? 194 ILE B C   1 
ATOM   2710  O O   . ILE B 2 172 ? 149.186 170.024 157.186 1.00 24.57  ? 194 ILE B O   1 
ATOM   2711  C CB  . ILE B 2 172 ? 150.434 170.329 160.157 1.00 24.57  ? 194 ILE B CB  1 
ATOM   2712  C CG1 . ILE B 2 172 ? 150.565 171.833 160.405 1.00 24.57  ? 194 ILE B CG1 1 
ATOM   2713  C CG2 . ILE B 2 172 ? 151.542 169.831 159.240 1.00 24.57  ? 194 ILE B CG2 1 
ATOM   2714  C CD1 . ILE B 2 172 ? 151.775 172.208 161.233 1.00 24.57  ? 194 ILE B CD1 1 
ATOM   2715  N N   . GLU B 2 173 ? 148.244 171.807 158.201 1.00 38.89  ? 195 GLU B N   1 
ATOM   2716  C CA  . GLU B 2 173 ? 148.012 172.557 156.973 1.00 38.89  ? 195 GLU B CA  1 
ATOM   2717  C C   . GLU B 2 173 ? 149.038 173.680 156.877 1.00 38.89  ? 195 GLU B C   1 
ATOM   2718  O O   . GLU B 2 173 ? 149.150 174.503 157.792 1.00 38.89  ? 195 GLU B O   1 
ATOM   2719  C CB  . GLU B 2 173 ? 146.592 173.120 156.933 1.00 38.89  ? 195 GLU B CB  1 
ATOM   2720  C CG  . GLU B 2 173 ? 146.339 174.073 155.776 1.00 38.89  ? 195 GLU B CG  1 
ATOM   2721  C CD  . GLU B 2 173 ? 144.878 174.450 155.640 1.00 38.89  ? 195 GLU B CD  1 
ATOM   2722  O OE1 . GLU B 2 173 ? 144.017 173.658 156.076 1.00 38.89  ? 195 GLU B OE1 1 
ATOM   2723  O OE2 . GLU B 2 173 ? 144.590 175.538 155.099 1.00 38.89  ? 195 GLU B OE2 1 
ATOM   2724  N N   . VAL B 2 174 ? 149.779 173.713 155.772 1.00 51.13  ? 196 VAL B N   1 
ATOM   2725  C CA  . VAL B 2 174 ? 150.852 174.677 155.565 1.00 51.13  ? 196 VAL B CA  1 
ATOM   2726  C C   . VAL B 2 174 ? 150.627 175.376 154.232 1.00 51.13  ? 196 VAL B C   1 
ATOM   2727  O O   . VAL B 2 174 ? 150.321 174.723 153.228 1.00 51.13  ? 196 VAL B O   1 
ATOM   2728  C CB  . VAL B 2 174 ? 152.237 174.001 155.593 1.00 51.13  ? 196 VAL B CB  1 
ATOM   2729  C CG1 . VAL B 2 174 ? 153.336 175.019 155.338 1.00 51.13  ? 196 VAL B CG1 1 
ATOM   2730  C CG2 . VAL B 2 174 ? 152.459 173.296 156.922 1.00 51.13  ? 196 VAL B CG2 1 
ATOM   2731  N N   . TRP B 2 175 ? 150.774 176.700 154.223 1.00 82.10  ? 197 TRP B N   1 
ATOM   2732  C CA  . TRP B 2 175 ? 150.680 177.476 152.996 1.00 82.10  ? 197 TRP B CA  1 
ATOM   2733  C C   . TRP B 2 175 ? 151.619 178.669 153.090 1.00 82.10  ? 197 TRP B C   1 
ATOM   2734  O O   . TRP B 2 175 ? 151.823 179.233 154.168 1.00 82.10  ? 197 TRP B O   1 
ATOM   2735  C CB  . TRP B 2 175 ? 149.242 177.941 152.725 1.00 82.10  ? 197 TRP B CB  1 
ATOM   2736  C CG  . TRP B 2 175 ? 148.806 179.117 153.551 1.00 82.10  ? 197 TRP B CG  1 
ATOM   2737  C CD1 . TRP B 2 175 ? 148.991 180.437 153.260 1.00 82.10  ? 197 TRP B CD1 1 
ATOM   2738  C CD2 . TRP B 2 175 ? 148.100 179.076 154.796 1.00 82.10  ? 197 TRP B CD2 1 
ATOM   2739  N NE1 . TRP B 2 175 ? 148.450 181.220 154.250 1.00 82.10  ? 197 TRP B NE1 1 
ATOM   2740  C CE2 . TRP B 2 175 ? 147.896 180.409 155.204 1.00 82.10  ? 197 TRP B CE2 1 
ATOM   2741  C CE3 . TRP B 2 175 ? 147.622 178.043 155.607 1.00 82.10  ? 197 TRP B CE3 1 
ATOM   2742  C CZ2 . TRP B 2 175 ? 147.236 180.735 156.387 1.00 82.10  ? 197 TRP B CZ2 1 
ATOM   2743  C CZ3 . TRP B 2 175 ? 146.967 178.369 156.781 1.00 82.10  ? 197 TRP B CZ3 1 
ATOM   2744  C CH2 . TRP B 2 175 ? 146.780 179.703 157.159 1.00 82.10  ? 197 TRP B CH2 1 
ATOM   2745  N N   . VAL B 2 176 ? 152.186 179.047 151.947 1.00 78.79  ? 198 VAL B N   1 
ATOM   2746  C CA  . VAL B 2 176 ? 153.120 180.163 151.855 1.00 78.79  ? 198 VAL B CA  1 
ATOM   2747  C C   . VAL B 2 176 ? 152.359 181.397 151.392 1.00 78.79  ? 198 VAL B C   1 
ATOM   2748  O O   . VAL B 2 176 ? 151.575 181.331 150.437 1.00 78.79  ? 198 VAL B O   1 
ATOM   2749  C CB  . VAL B 2 176 ? 154.281 179.842 150.899 1.00 78.79  ? 198 VAL B CB  1 
ATOM   2750  C CG1 . VAL B 2 176 ? 155.289 180.981 150.884 1.00 78.79  ? 198 VAL B CG1 1 
ATOM   2751  C CG2 . VAL B 2 176 ? 154.950 178.537 151.297 1.00 78.79  ? 198 VAL B CG2 1 
ATOM   2752  N N   . GLU B 2 177 ? 152.589 182.521 152.065 1.00 74.52  ? 199 GLU B N   1 
ATOM   2753  C CA  . GLU B 2 177 ? 151.939 183.786 151.745 1.00 74.52  ? 199 GLU B CA  1 
ATOM   2754  C C   . GLU B 2 177 ? 152.993 184.775 151.269 1.00 74.52  ? 199 GLU B C   1 
ATOM   2755  O O   . GLU B 2 177 ? 153.958 185.052 151.990 1.00 74.52  ? 199 GLU B O   1 
ATOM   2756  C CB  . GLU B 2 177 ? 151.186 184.338 152.957 1.00 74.52  ? 199 GLU B CB  1 
ATOM   2757  C CG  . GLU B 2 177 ? 150.634 185.740 152.763 1.00 74.52  ? 199 GLU B CG  1 
ATOM   2758  C CD  . GLU B 2 177 ? 149.791 186.199 153.936 1.00 74.52  ? 199 GLU B CD  1 
ATOM   2759  O OE1 . GLU B 2 177 ? 149.637 185.420 154.900 1.00 74.52  ? 199 GLU B OE1 1 
ATOM   2760  O OE2 . GLU B 2 177 ? 149.281 187.338 153.894 1.00 74.52  ? 199 GLU B OE2 1 
ATOM   2761  N N   . ALA B 2 178 ? 152.808 185.302 150.062 1.00 66.70  ? 200 ALA B N   1 
ATOM   2762  C CA  . ALA B 2 178 ? 153.732 186.269 149.485 1.00 66.70  ? 200 ALA B CA  1 
ATOM   2763  C C   . ALA B 2 178 ? 153.266 187.677 149.831 1.00 66.70  ? 200 ALA B C   1 
ATOM   2764  O O   . ALA B 2 178 ? 152.152 188.074 149.470 1.00 66.70  ? 200 ALA B O   1 
ATOM   2765  C CB  . ALA B 2 178 ? 153.830 186.089 147.971 1.00 66.70  ? 200 ALA B CB  1 
ATOM   2766  N N   . GLU B 2 179 ? 154.117 188.429 150.525 1.00 73.26  ? 201 GLU B N   1 
ATOM   2767  C CA  . GLU B 2 179 ? 153.793 189.774 150.978 1.00 73.26  ? 201 GLU B CA  1 
ATOM   2768  C C   . GLU B 2 179 ? 154.891 190.730 150.543 1.00 73.26  ? 201 GLU B C   1 
ATOM   2769  O O   . GLU B 2 179 ? 156.078 190.448 150.737 1.00 73.26  ? 201 GLU B O   1 
ATOM   2770  C CB  . GLU B 2 179 ? 153.626 189.819 152.501 1.00 73.26  ? 201 GLU B CB  1 
ATOM   2771  C CG  . GLU B 2 179 ? 153.449 191.218 153.066 1.00 73.26  ? 201 GLU B CG  1 
ATOM   2772  C CD  . GLU B 2 179 ? 153.479 191.241 154.581 1.00 73.26  ? 201 GLU B CD  1 
ATOM   2773  O OE1 . GLU B 2 179 ? 153.342 192.338 155.163 1.00 73.26  ? 201 GLU B OE1 1 
ATOM   2774  O OE2 . GLU B 2 179 ? 153.641 190.163 155.190 1.00 73.26  ? 201 GLU B OE2 1 
ATOM   2775  N N   . ASN B 2 180 ? 154.494 191.856 149.957 1.00 68.28  ? 202 ASN B N   1 
ATOM   2776  C CA  . ASN B 2 180 ? 155.431 192.886 149.531 1.00 68.28  ? 202 ASN B CA  1 
ATOM   2777  C C   . ASN B 2 180 ? 154.809 194.245 149.832 1.00 68.28  ? 202 ASN B C   1 
ATOM   2778  O O   . ASN B 2 180 ? 153.804 194.347 150.543 1.00 68.28  ? 202 ASN B O   1 
ATOM   2779  C CB  . ASN B 2 180 ? 155.789 192.716 148.048 1.00 68.28  ? 202 ASN B CB  1 
ATOM   2780  C CG  . ASN B 2 180 ? 154.676 193.163 147.125 1.00 68.28  ? 202 ASN B CG  1 
ATOM   2781  O OD1 . ASN B 2 180 ? 153.611 192.548 147.072 1.00 68.28  ? 202 ASN B OD1 1 
ATOM   2782  N ND2 . ASN B 2 180 ? 154.918 194.240 146.387 1.00 68.28  ? 202 ASN B ND2 1 
ATOM   2783  N N   . ALA B 2 181 ? 155.411 195.300 149.285 1.00 72.23  ? 203 ALA B N   1 
ATOM   2784  C CA  . ALA B 2 181 ? 154.952 196.661 149.530 1.00 72.23  ? 203 ALA B CA  1 
ATOM   2785  C C   . ALA B 2 181 ? 153.791 197.077 148.636 1.00 72.23  ? 203 ALA B C   1 
ATOM   2786  O O   . ALA B 2 181 ? 153.387 198.244 148.682 1.00 72.23  ? 203 ALA B O   1 
ATOM   2787  C CB  . ALA B 2 181 ? 156.113 197.644 149.353 1.00 72.23  ? 203 ALA B CB  1 
ATOM   2788  N N   . LEU B 2 182 ? 153.244 196.163 147.831 1.00 69.17  ? 204 LEU B N   1 
ATOM   2789  C CA  . LEU B 2 182 ? 152.152 196.491 146.923 1.00 69.17  ? 204 LEU B CA  1 
ATOM   2790  C C   . LEU B 2 182 ? 150.956 195.558 147.073 1.00 69.17  ? 204 LEU B C   1 
ATOM   2791  O O   . LEU B 2 182 ? 149.999 195.670 146.298 1.00 69.17  ? 204 LEU B O   1 
ATOM   2792  C CB  . LEU B 2 182 ? 152.639 196.478 145.469 1.00 69.17  ? 204 LEU B CB  1 
ATOM   2793  C CG  . LEU B 2 182 ? 153.753 197.467 145.120 1.00 69.17  ? 204 LEU B CG  1 
ATOM   2794  C CD1 . LEU B 2 182 ? 154.150 197.337 143.658 1.00 69.17  ? 204 LEU B CD1 1 
ATOM   2795  C CD2 . LEU B 2 182 ? 153.325 198.890 145.436 1.00 69.17  ? 204 LEU B CD2 1 
ATOM   2796  N N   . GLY B 2 183 ? 150.980 194.650 148.032 1.00 69.39  ? 205 GLY B N   1 
ATOM   2797  C CA  . GLY B 2 183 ? 149.860 193.757 148.253 1.00 69.39  ? 205 GLY B CA  1 
ATOM   2798  C C   . GLY B 2 183 ? 150.329 192.437 148.828 1.00 69.39  ? 205 GLY B C   1 
ATOM   2799  O O   . GLY B 2 183 ? 151.520 192.189 148.998 1.00 69.39  ? 205 GLY B O   1 
ATOM   2800  N N   . LYS B 2 184 ? 149.350 191.586 149.127 1.00 55.69  ? 206 LYS B N   1 
ATOM   2801  C CA  . LYS B 2 184 ? 149.597 190.260 149.671 1.00 55.69  ? 206 LYS B CA  1 
ATOM   2802  C C   . LYS B 2 184 ? 148.851 189.224 148.845 1.00 55.69  ? 206 LYS B C   1 
ATOM   2803  O O   . LYS B 2 184 ? 147.813 189.514 148.244 1.00 55.69  ? 206 LYS B O   1 
ATOM   2804  C CB  . LYS B 2 184 ? 149.166 190.160 151.141 1.00 55.69  ? 206 LYS B CB  1 
ATOM   2805  C CG  . LYS B 2 184 ? 149.879 191.126 152.070 1.00 55.69  ? 206 LYS B CG  1 
ATOM   2806  C CD  . LYS B 2 184 ? 149.402 190.960 153.504 1.00 55.69  ? 206 LYS B CD  1 
ATOM   2807  C CE  . LYS B 2 184 ? 150.048 191.983 154.424 1.00 55.69  ? 206 LYS B CE  1 
ATOM   2808  N NZ  . LYS B 2 184 ? 149.611 191.816 155.837 1.00 55.69  ? 206 LYS B NZ  1 
ATOM   2809  N N   . VAL B 2 185 ? 149.390 188.008 148.824 1.00 52.70  ? 207 VAL B N   1 
ATOM   2810  C CA  . VAL B 2 185 ? 148.783 186.905 148.089 1.00 52.70  ? 207 VAL B CA  1 
ATOM   2811  C C   . VAL B 2 185 ? 149.273 185.603 148.708 1.00 52.70  ? 207 VAL B C   1 
ATOM   2812  O O   . VAL B 2 185 ? 150.446 185.472 149.068 1.00 52.70  ? 207 VAL B O   1 
ATOM   2813  C CB  . VAL B 2 185 ? 149.106 186.992 146.578 1.00 52.70  ? 207 VAL B CB  1 
ATOM   2814  C CG1 . VAL B 2 185 ? 150.609 187.051 146.348 1.00 52.70  ? 207 VAL B CG1 1 
ATOM   2815  C CG2 . VAL B 2 185 ? 148.482 185.826 145.824 1.00 52.70  ? 207 VAL B CG2 1 
ATOM   2816  N N   . THR B 2 186 ? 148.360 184.645 148.842 1.00 50.35  ? 208 THR B N   1 
ATOM   2817  C CA  . THR B 2 186 ? 148.653 183.357 149.448 1.00 50.35  ? 208 THR B CA  1 
ATOM   2818  C C   . THR B 2 186 ? 148.629 182.259 148.392 1.00 50.35  ? 208 THR B C   1 
ATOM   2819  O O   . THR B 2 186 ? 147.916 182.352 147.389 1.00 50.35  ? 208 THR B O   1 
ATOM   2820  C CB  . THR B 2 186 ? 147.649 183.024 150.555 1.00 50.35  ? 208 THR B CB  1 
ATOM   2821  O OG1 . THR B 2 186 ? 146.351 182.826 149.981 1.00 50.35  ? 208 THR B OG1 1 
ATOM   2822  C CG2 . THR B 2 186 ? 147.580 184.155 151.568 1.00 50.35  ? 208 THR B CG2 1 
ATOM   2823  N N   . SER B 2 187 ? 149.415 181.215 148.632 1.00 53.21  ? 209 SER B N   1 
ATOM   2824  C CA  . SER B 2 187 ? 149.472 180.068 147.741 1.00 53.21  ? 209 SER B CA  1 
ATOM   2825  C C   . SER B 2 187 ? 148.371 179.077 148.117 1.00 53.21  ? 209 SER B C   1 
ATOM   2826  O O   . SER B 2 187 ? 147.473 179.381 148.906 1.00 53.21  ? 209 SER B O   1 
ATOM   2827  C CB  . SER B 2 187 ? 150.859 179.430 147.790 1.00 53.21  ? 209 SER B CB  1 
ATOM   2828  O OG  . SER B 2 187 ? 151.861 180.357 147.413 1.00 53.21  ? 209 SER B OG  1 
ATOM   2829  N N   . ASP B 2 188 ? 148.431 177.876 147.550 1.00 67.43  ? 210 ASP B N   1 
ATOM   2830  C CA  . ASP B 2 188 ? 147.433 176.861 147.846 1.00 67.43  ? 210 ASP B CA  1 
ATOM   2831  C C   . ASP B 2 188 ? 147.631 176.305 149.254 1.00 67.43  ? 210 ASP B C   1 
ATOM   2832  O O   . ASP B 2 188 ? 148.716 176.378 149.837 1.00 67.43  ? 210 ASP B O   1 
ATOM   2833  C CB  . ASP B 2 188 ? 147.499 175.730 146.819 1.00 67.43  ? 210 ASP B CB  1 
ATOM   2834  C CG  . ASP B 2 188 ? 147.229 176.210 145.408 1.00 67.43  ? 210 ASP B CG  1 
ATOM   2835  O OD1 . ASP B 2 188 ? 146.411 177.138 145.241 1.00 67.43  ? 210 ASP B OD1 1 
ATOM   2836  O OD2 . ASP B 2 188 ? 147.837 175.660 144.465 1.00 67.43  ? 210 ASP B OD2 1 
ATOM   2837  N N   . HIS B 2 189 ? 146.556 175.744 149.799 1.00 82.10  ? 211 HIS B N   1 
ATOM   2838  C CA  . HIS B 2 189 ? 146.561 175.165 151.136 1.00 82.10  ? 211 HIS B CA  1 
ATOM   2839  C C   . HIS B 2 189 ? 146.563 173.645 151.021 1.00 82.10  ? 211 HIS B C   1 
ATOM   2840  O O   . HIS B 2 189 ? 145.643 173.061 150.439 1.00 82.10  ? 211 HIS B O   1 
ATOM   2841  C CB  . HIS B 2 189 ? 145.353 175.644 151.940 1.00 82.10  ? 211 HIS B CB  1 
ATOM   2842  C CG  . HIS B 2 189 ? 145.152 177.127 151.906 1.00 82.10  ? 211 HIS B CG  1 
ATOM   2843  N ND1 . HIS B 2 189 ? 145.916 177.999 152.652 1.00 82.10  ? 211 HIS B ND1 1 
ATOM   2844  C CD2 . HIS B 2 189 ? 144.273 177.893 151.217 1.00 82.10  ? 211 HIS B CD2 1 
ATOM   2845  C CE1 . HIS B 2 189 ? 145.517 179.238 152.423 1.00 82.10  ? 211 HIS B CE1 1 
ATOM   2846  N NE2 . HIS B 2 189 ? 144.521 179.201 151.556 1.00 82.10  ? 211 HIS B NE2 1 
ATOM   2847  N N   . ILE B 2 190 ? 147.594 173.011 151.577 1.00 72.00  ? 212 ILE B N   1 
ATOM   2848  C CA  . ILE B 2 190 ? 147.738 171.561 151.540 1.00 72.00  ? 212 ILE B CA  1 
ATOM   2849  C C   . ILE B 2 190 ? 147.880 171.042 152.964 1.00 72.00  ? 212 ILE B C   1 
ATOM   2850  O O   . ILE B 2 190 ? 148.375 171.738 153.856 1.00 72.00  ? 212 ILE B O   1 
ATOM   2851  C CB  . ILE B 2 190 ? 148.943 171.121 150.681 1.00 72.00  ? 212 ILE B CB  1 
ATOM   2852  C CG1 . ILE B 2 190 ? 150.247 171.666 151.267 1.00 72.00  ? 212 ILE B CG1 1 
ATOM   2853  C CG2 . ILE B 2 190 ? 148.767 171.575 149.241 1.00 72.00  ? 212 ILE B CG2 1 
ATOM   2854  C CD1 . ILE B 2 190 ? 151.490 171.149 150.578 1.00 72.00  ? 212 ILE B CD1 1 
ATOM   2855  N N   . ASN B 2 191 ? 147.435 169.804 153.171 1.00 82.10  ? 213 ASN B N   1 
ATOM   2856  C CA  . ASN B 2 191 ? 147.523 169.139 154.462 1.00 82.10  ? 213 ASN B CA  1 
ATOM   2857  C C   . ASN B 2 191 ? 148.193 167.785 154.287 1.00 82.10  ? 213 ASN B C   1 
ATOM   2858  O O   . ASN B 2 191 ? 147.878 167.045 153.350 1.00 82.10  ? 213 ASN B O   1 
ATOM   2859  C CB  . ASN B 2 191 ? 146.137 168.967 155.096 1.00 82.10  ? 213 ASN B CB  1 
ATOM   2860  C CG  . ASN B 2 191 ? 145.091 168.516 154.097 1.00 82.10  ? 213 ASN B CG  1 
ATOM   2861  O OD1 . ASN B 2 191 ? 145.384 168.327 152.917 1.00 82.10  ? 213 ASN B OD1 1 
ATOM   2862  N ND2 . ASN B 2 191 ? 143.862 168.344 154.566 1.00 82.10  ? 213 ASN B ND2 1 
ATOM   2863  N N   . PHE B 2 192 ? 149.114 167.462 155.191 1.00 82.10  ? 214 PHE B N   1 
ATOM   2864  C CA  . PHE B 2 192 ? 149.869 166.224 155.074 1.00 82.10  ? 214 PHE B CA  1 
ATOM   2865  C C   . PHE B 2 192 ? 150.374 165.803 156.445 1.00 82.10  ? 214 PHE B C   1 
ATOM   2866  O O   . PHE B 2 192 ? 150.539 166.631 157.345 1.00 82.10  ? 214 PHE B O   1 
ATOM   2867  C CB  . PHE B 2 192 ? 151.044 166.374 154.101 1.00 82.10  ? 214 PHE B CB  1 
ATOM   2868  C CG  . PHE B 2 192 ? 152.082 167.363 154.549 1.00 82.10  ? 214 PHE B CG  1 
ATOM   2869  C CD1 . PHE B 2 192 ? 151.898 168.720 154.344 1.00 82.10  ? 214 PHE B CD1 1 
ATOM   2870  C CD2 . PHE B 2 192 ? 153.243 166.936 155.170 1.00 82.10  ? 214 PHE B CD2 1 
ATOM   2871  C CE1 . PHE B 2 192 ? 152.850 169.631 154.753 1.00 82.10  ? 214 PHE B CE1 1 
ATOM   2872  C CE2 . PHE B 2 192 ? 154.199 167.843 155.582 1.00 82.10  ? 214 PHE B CE2 1 
ATOM   2873  C CZ  . PHE B 2 192 ? 154.002 169.192 155.372 1.00 82.10  ? 214 PHE B CZ  1 
ATOM   2874  N N   . ASP B 2 193 ? 150.623 164.509 156.583 1.00 40.19  ? 215 ASP B N   1 
ATOM   2875  C CA  . ASP B 2 193 ? 151.143 163.893 157.797 1.00 40.19  ? 215 ASP B CA  1 
ATOM   2876  C C   . ASP B 2 193 ? 152.668 163.936 157.774 1.00 40.19  ? 215 ASP B C   1 
ATOM   2877  O O   . ASP B 2 193 ? 153.278 163.432 156.824 1.00 40.19  ? 215 ASP B O   1 
ATOM   2878  C CB  . ASP B 2 193 ? 150.655 162.452 157.900 1.00 40.19  ? 215 ASP B CB  1 
ATOM   2879  C CG  . ASP B 2 193 ? 150.870 161.848 159.274 1.00 40.19  ? 215 ASP B CG  1 
ATOM   2880  O OD1 . ASP B 2 193 ? 151.439 162.524 160.152 1.00 40.19  ? 215 ASP B OD1 1 
ATOM   2881  O OD2 . ASP B 2 193 ? 150.453 160.690 159.479 1.00 40.19  ? 215 ASP B OD2 1 
ATOM   2882  N N   . PRO B 2 194 ? 153.314 164.532 158.781 1.00 32.06  ? 216 PRO B N   1 
ATOM   2883  C CA  . PRO B 2 194 ? 154.783 164.641 158.749 1.00 32.06  ? 216 PRO B CA  1 
ATOM   2884  C C   . PRO B 2 194 ? 155.506 163.307 158.718 1.00 32.06  ? 216 PRO B C   1 
ATOM   2885  O O   . PRO B 2 194 ? 156.666 163.264 158.293 1.00 32.06  ? 216 PRO B O   1 
ATOM   2886  C CB  . PRO B 2 194 ? 155.106 165.420 160.032 1.00 32.06  ? 216 PRO B CB  1 
ATOM   2887  C CG  . PRO B 2 194 ? 153.860 166.168 160.340 1.00 32.06  ? 216 PRO B CG  1 
ATOM   2888  C CD  . PRO B 2 194 ? 152.732 165.287 159.902 1.00 32.06  ? 216 PRO B CD  1 
ATOM   2889  N N   . VAL B 2 195 ? 154.869 162.218 159.155 1.00 42.26  ? 217 VAL B N   1 
ATOM   2890  C CA  . VAL B 2 195 ? 155.517 160.915 159.075 1.00 42.26  ? 217 VAL B CA  1 
ATOM   2891  C C   . VAL B 2 195 ? 155.632 160.444 157.631 1.00 42.26  ? 217 VAL B C   1 
ATOM   2892  O O   . VAL B 2 195 ? 156.492 159.613 157.318 1.00 42.26  ? 217 VAL B O   1 
ATOM   2893  C CB  . VAL B 2 195 ? 154.765 159.887 159.943 1.00 42.26  ? 217 VAL B CB  1 
ATOM   2894  C CG1 . VAL B 2 195 ? 153.460 159.474 159.280 1.00 42.26  ? 217 VAL B CG1 1 
ATOM   2895  C CG2 . VAL B 2 195 ? 155.644 158.676 160.225 1.00 42.26  ? 217 VAL B CG2 1 
ATOM   2896  N N   . TYR B 2 196 ? 154.795 160.968 156.733 1.00 24.05  ? 218 TYR B N   1 
ATOM   2897  C CA  . TYR B 2 196 ? 154.861 160.614 155.322 1.00 24.05  ? 218 TYR B CA  1 
ATOM   2898  C C   . TYR B 2 196 ? 155.985 161.326 154.583 1.00 24.05  ? 218 TYR B C   1 
ATOM   2899  O O   . TYR B 2 196 ? 156.285 160.957 153.443 1.00 24.05  ? 218 TYR B O   1 
ATOM   2900  C CB  . TYR B 2 196 ? 153.525 160.923 154.642 1.00 24.05  ? 218 TYR B CB  1 
ATOM   2901  C CG  . TYR B 2 196 ? 152.512 159.807 154.752 1.00 24.05  ? 218 TYR B CG  1 
ATOM   2902  C CD1 . TYR B 2 196 ? 152.054 159.145 153.622 1.00 24.05  ? 218 TYR B CD1 1 
ATOM   2903  C CD2 . TYR B 2 196 ? 152.018 159.410 155.987 1.00 24.05  ? 218 TYR B CD2 1 
ATOM   2904  C CE1 . TYR B 2 196 ? 151.130 158.123 153.717 1.00 24.05  ? 218 TYR B CE1 1 
ATOM   2905  C CE2 . TYR B 2 196 ? 151.094 158.389 156.093 1.00 24.05  ? 218 TYR B CE2 1 
ATOM   2906  C CZ  . TYR B 2 196 ? 150.653 157.749 154.955 1.00 24.05  ? 218 TYR B CZ  1 
ATOM   2907  O OH  . TYR B 2 196 ? 149.733 156.731 155.053 1.00 24.05  ? 218 TYR B OH  1 
ATOM   2908  N N   . LYS B 2 197 ? 156.611 162.330 155.198 1.00 28.71  ? 219 LYS B N   1 
ATOM   2909  C CA  . LYS B 2 197 ? 157.712 163.063 154.587 1.00 28.71  ? 219 LYS B CA  1 
ATOM   2910  C C   . LYS B 2 197 ? 159.034 162.819 155.307 1.00 28.71  ? 219 LYS B C   1 
ATOM   2911  O O   . LYS B 2 197 ? 159.961 163.625 155.184 1.00 28.71  ? 219 LYS B O   1 
ATOM   2912  C CB  . LYS B 2 197 ? 157.400 164.559 154.553 1.00 28.71  ? 219 LYS B CB  1 
ATOM   2913  C CG  . LYS B 2 197 ? 156.050 164.905 153.950 1.00 28.71  ? 219 LYS B CG  1 
ATOM   2914  C CD  . LYS B 2 197 ? 155.985 164.538 152.478 1.00 28.71  ? 219 LYS B CD  1 
ATOM   2915  C CE  . LYS B 2 197 ? 154.664 164.969 151.864 1.00 28.71  ? 219 LYS B CE  1 
ATOM   2916  N NZ  . LYS B 2 197 ? 154.596 164.654 150.412 1.00 28.71  ? 219 LYS B NZ  1 
ATOM   2917  N N   . VAL B 2 198 ? 159.138 161.726 156.055 1.00 25.37  ? 220 VAL B N   1 
ATOM   2918  C CA  . VAL B 2 198 ? 160.341 161.437 156.827 1.00 25.37  ? 220 VAL B CA  1 
ATOM   2919  C C   . VAL B 2 198 ? 161.407 160.864 155.905 1.00 25.37  ? 220 VAL B C   1 
ATOM   2920  O O   . VAL B 2 198 ? 161.161 159.898 155.173 1.00 25.37  ? 220 VAL B O   1 
ATOM   2921  C CB  . VAL B 2 198 ? 160.028 160.470 157.980 1.00 25.37  ? 220 VAL B CB  1 
ATOM   2922  C CG1 . VAL B 2 198 ? 161.315 159.960 158.608 1.00 25.37  ? 220 VAL B CG1 1 
ATOM   2923  C CG2 . VAL B 2 198 ? 159.164 161.156 159.023 1.00 25.37  ? 220 VAL B CG2 1 
ATOM   2924  N N   . LYS B 2 199 ? 162.599 161.462 155.938 1.00 50.84  ? 221 LYS B N   1 
ATOM   2925  C CA  . LYS B 2 199 ? 163.744 160.959 155.194 1.00 50.84  ? 221 LYS B CA  1 
ATOM   2926  C C   . LYS B 2 199 ? 164.610 160.137 156.138 1.00 50.84  ? 221 LYS B C   1 
ATOM   2927  O O   . LYS B 2 199 ? 165.306 160.710 156.989 1.00 50.84  ? 221 LYS B O   1 
ATOM   2928  C CB  . LYS B 2 199 ? 164.549 162.111 154.588 1.00 50.84  ? 221 LYS B CB  1 
ATOM   2929  C CG  . LYS B 2 199 ? 165.732 161.666 153.744 1.00 50.84  ? 221 LYS B CG  1 
ATOM   2930  C CD  . LYS B 2 199 ? 166.476 162.857 153.165 1.00 50.84  ? 221 LYS B CD  1 
ATOM   2931  C CE  . LYS B 2 199 ? 167.613 162.412 152.261 1.00 50.84  ? 221 LYS B CE  1 
ATOM   2932  N NZ  . LYS B 2 199 ? 168.609 161.580 152.992 1.00 50.84  ? 221 LYS B NZ  1 
ATOM   2933  N N   . PRO B 2 200 ? 164.603 158.810 156.041 1.00 56.56  ? 222 PRO B N   1 
ATOM   2934  C CA  . PRO B 2 200 ? 165.351 157.993 157.002 1.00 56.56  ? 222 PRO B CA  1 
ATOM   2935  C C   . PRO B 2 200 ? 166.853 158.190 156.870 1.00 56.56  ? 222 PRO B C   1 
ATOM   2936  O O   . PRO B 2 200 ? 167.366 158.673 155.858 1.00 56.56  ? 222 PRO B O   1 
ATOM   2937  C CB  . PRO B 2 200 ? 164.950 156.556 156.643 1.00 56.56  ? 222 PRO B CB  1 
ATOM   2938  C CG  . PRO B 2 200 ? 163.705 156.689 155.818 1.00 56.56  ? 222 PRO B CG  1 
ATOM   2939  C CD  . PRO B 2 200 ? 163.844 157.985 155.088 1.00 56.56  ? 222 PRO B CD  1 
ATOM   2940  N N   . ASN B 2 201 ? 167.558 157.806 157.928 1.00 83.13  ? 223 ASN B N   1 
ATOM   2941  C CA  . ASN B 2 201 ? 169.011 157.879 157.946 1.00 83.13  ? 223 ASN B CA  1 
ATOM   2942  C C   . ASN B 2 201 ? 169.605 156.641 157.276 1.00 83.13  ? 223 ASN B C   1 
ATOM   2943  O O   . ASN B 2 201 ? 169.100 155.531 157.468 1.00 83.13  ? 223 ASN B O   1 
ATOM   2944  C CB  . ASN B 2 201 ? 169.522 157.991 159.382 1.00 83.13  ? 223 ASN B CB  1 
ATOM   2945  C CG  . ASN B 2 201 ? 170.983 158.387 159.453 1.00 83.13  ? 223 ASN B CG  1 
ATOM   2946  O OD1 . ASN B 2 201 ? 171.872 157.539 159.387 1.00 83.13  ? 223 ASN B OD1 1 
ATOM   2947  N ND2 . ASN B 2 201 ? 171.238 159.683 159.590 1.00 83.13  ? 223 ASN B ND2 1 
ATOM   2948  N N   . PRO B 2 202 ? 170.660 156.801 156.482 1.00 78.50  ? 224 PRO B N   1 
ATOM   2949  C CA  . PRO B 2 202 ? 171.281 155.645 155.825 1.00 78.50  ? 224 PRO B CA  1 
ATOM   2950  C C   . PRO B 2 202 ? 171.855 154.682 156.847 1.00 78.50  ? 224 PRO B C   1 
ATOM   2951  O O   . PRO B 2 202 ? 172.464 155.107 157.840 1.00 78.50  ? 224 PRO B O   1 
ATOM   2952  C CB  . PRO B 2 202 ? 172.390 156.277 154.969 1.00 78.50  ? 224 PRO B CB  1 
ATOM   2953  C CG  . PRO B 2 202 ? 172.638 157.616 155.586 1.00 78.50  ? 224 PRO B CG  1 
ATOM   2954  C CD  . PRO B 2 202 ? 171.309 158.067 156.102 1.00 78.50  ? 224 PRO B CD  1 
ATOM   2955  N N   . PRO B 2 203 ? 171.673 153.377 156.644 1.00 75.73  ? 225 PRO B N   1 
ATOM   2956  C CA  . PRO B 2 203 ? 172.207 152.402 157.602 1.00 75.73  ? 225 PRO B CA  1 
ATOM   2957  C C   . PRO B 2 203 ? 173.726 152.452 157.659 1.00 75.73  ? 225 PRO B C   1 
ATOM   2958  O O   . PRO B 2 203 ? 174.400 152.668 156.650 1.00 75.73  ? 225 PRO B O   1 
ATOM   2959  C CB  . PRO B 2 203 ? 171.707 151.058 157.057 1.00 75.73  ? 225 PRO B CB  1 
ATOM   2960  C CG  . PRO B 2 203 ? 170.546 151.405 156.179 1.00 75.73  ? 225 PRO B CG  1 
ATOM   2961  C CD  . PRO B 2 203 ? 170.882 152.736 155.582 1.00 75.73  ? 225 PRO B CD  1 
ATOM   2962  N N   . HIS B 2 204 ? 174.260 152.252 158.859 1.00 78.77  ? 226 HIS B N   1 
ATOM   2963  C CA  . HIS B 2 204 ? 175.691 152.297 159.112 1.00 78.77  ? 226 HIS B CA  1 
ATOM   2964  C C   . HIS B 2 204 ? 176.162 150.960 159.668 1.00 78.77  ? 226 HIS B C   1 
ATOM   2965  O O   . HIS B 2 204 ? 175.362 150.107 160.065 1.00 78.77  ? 226 HIS B O   1 
ATOM   2966  C CB  . HIS B 2 204 ? 176.041 153.430 160.086 1.00 78.77  ? 226 HIS B CB  1 
ATOM   2967  C CG  . HIS B 2 204 ? 175.179 153.461 161.309 1.00 78.77  ? 226 HIS B CG  1 
ATOM   2968  N ND1 . HIS B 2 204 ? 174.079 154.283 161.425 1.00 78.77  ? 226 HIS B ND1 1 
ATOM   2969  C CD2 . HIS B 2 204 ? 175.252 152.766 162.469 1.00 78.77  ? 226 HIS B CD2 1 
ATOM   2970  C CE1 . HIS B 2 204 ? 173.513 154.096 162.604 1.00 78.77  ? 226 HIS B CE1 1 
ATOM   2971  N NE2 . HIS B 2 204 ? 174.205 153.180 163.257 1.00 78.77  ? 226 HIS B NE2 1 
ATOM   2972  N N   . ASN B 2 205 ? 177.485 150.789 159.688 1.00 86.54  ? 227 ASN B N   1 
ATOM   2973  C CA  . ASN B 2 205 ? 178.132 149.592 160.227 1.00 86.54  ? 227 ASN B CA  1 
ATOM   2974  C C   . ASN B 2 205 ? 177.634 148.331 159.517 1.00 86.54  ? 227 ASN B C   1 
ATOM   2975  O O   . ASN B 2 205 ? 177.005 147.451 160.108 1.00 86.54  ? 227 ASN B O   1 
ATOM   2976  C CB  . ASN B 2 205 ? 177.931 149.501 161.746 1.00 86.54  ? 227 ASN B CB  1 
ATOM   2977  C CG  . ASN B 2 205 ? 178.839 148.470 162.399 1.00 86.54  ? 227 ASN B CG  1 
ATOM   2978  O OD1 . ASN B 2 205 ? 178.506 147.286 162.448 1.00 86.54  ? 227 ASN B OD1 1 
ATOM   2979  N ND2 . ASN B 2 205 ? 179.988 148.913 162.909 1.00 86.54  ? 227 ASN B ND2 1 
ATOM   2980  N N   . LEU B 2 206 ? 177.921 148.268 158.220 1.00 56.58  ? 228 LEU B N   1 
ATOM   2981  C CA  . LEU B 2 206 ? 177.571 147.115 157.402 1.00 56.58  ? 228 LEU B CA  1 
ATOM   2982  C C   . LEU B 2 206 ? 178.739 146.139 157.371 1.00 56.58  ? 228 LEU B C   1 
ATOM   2983  O O   . LEU B 2 206 ? 179.873 146.529 157.075 1.00 56.58  ? 228 LEU B O   1 
ATOM   2984  C CB  . LEU B 2 206 ? 177.204 147.550 155.983 1.00 56.58  ? 228 LEU B CB  1 
ATOM   2985  C CG  . LEU B 2 206 ? 176.970 146.427 154.972 1.00 56.58  ? 228 LEU B CG  1 
ATOM   2986  C CD1 . LEU B 2 206 ? 175.806 145.551 155.405 1.00 56.58  ? 228 LEU B CD1 1 
ATOM   2987  C CD2 . LEU B 2 206 ? 176.730 146.997 153.583 1.00 56.58  ? 228 LEU B CD2 1 
ATOM   2988  N N   . SER B 2 207 ? 178.459 144.874 157.675 1.00 48.06  ? 229 SER B N   1 
ATOM   2989  C CA  . SER B 2 207 ? 179.480 143.839 157.717 1.00 48.06  ? 229 SER B CA  1 
ATOM   2990  C C   . SER B 2 207 ? 179.039 142.643 156.887 1.00 48.06  ? 229 SER B C   1 
ATOM   2991  O O   . SER B 2 207 ? 177.849 142.325 156.806 1.00 48.06  ? 229 SER B O   1 
ATOM   2992  C CB  . SER B 2 207 ? 179.771 143.396 159.157 1.00 48.06  ? 229 SER B CB  1 
ATOM   2993  O OG  . SER B 2 207 ? 178.591 142.952 159.802 1.00 48.06  ? 229 SER B OG  1 
ATOM   2994  N N   . VAL B 2 208 ? 180.016 141.983 156.270 1.00 48.51  ? 230 VAL B N   1 
ATOM   2995  C CA  . VAL B 2 208 ? 179.786 140.806 155.441 1.00 48.51  ? 230 VAL B CA  1 
ATOM   2996  C C   . VAL B 2 208 ? 180.445 139.613 156.117 1.00 48.51  ? 230 VAL B C   1 
ATOM   2997  O O   . VAL B 2 208 ? 181.635 139.661 156.449 1.00 48.51  ? 230 VAL B O   1 
ATOM   2998  C CB  . VAL B 2 208 ? 180.337 140.997 154.015 1.00 48.51  ? 230 VAL B CB  1 
ATOM   2999  C CG1 . VAL B 2 208 ? 179.934 139.828 153.130 1.00 48.51  ? 230 VAL B CG1 1 
ATOM   3000  C CG2 . VAL B 2 208 ? 179.852 142.314 153.429 1.00 48.51  ? 230 VAL B CG2 1 
ATOM   3001  N N   . ILE B 2 209 ? 179.674 138.548 156.318 1.00 59.48  ? 231 ILE B N   1 
ATOM   3002  C CA  . ILE B 2 209 ? 180.152 137.331 156.961 1.00 59.48  ? 231 ILE B CA  1 
ATOM   3003  C C   . ILE B 2 209 ? 179.940 136.168 156.004 1.00 59.48  ? 231 ILE B C   1 
ATOM   3004  O O   . ILE B 2 209 ? 178.832 135.974 155.491 1.00 59.48  ? 231 ILE B O   1 
ATOM   3005  C CB  . ILE B 2 209 ? 179.437 137.076 158.300 1.00 59.48  ? 231 ILE B CB  1 
ATOM   3006  C CG1 . ILE B 2 209 ? 179.651 138.254 159.252 1.00 59.48  ? 231 ILE B CG1 1 
ATOM   3007  C CG2 . ILE B 2 209 ? 179.929 135.782 158.930 1.00 59.48  ? 231 ILE B CG2 1 
ATOM   3008  C CD1 . ILE B 2 209 ? 178.977 138.084 160.596 1.00 59.48  ? 231 ILE B CD1 1 
ATOM   3009  N N   . ASN B 2 210 ? 180.998 135.398 155.768 1.00 83.01  ? 232 ASN B N   1 
ATOM   3010  C CA  . ASN B 2 210 ? 180.934 134.248 154.880 1.00 83.01  ? 232 ASN B CA  1 
ATOM   3011  C C   . ASN B 2 210 ? 180.517 133.010 155.672 1.00 83.01  ? 232 ASN B C   1 
ATOM   3012  O O   . ASN B 2 210 ? 180.113 133.094 156.835 1.00 83.01  ? 232 ASN B O   1 
ATOM   3013  C CB  . ASN B 2 210 ? 182.273 134.051 154.173 1.00 83.01  ? 232 ASN B CB  1 
ATOM   3014  C CG  . ASN B 2 210 ? 183.453 134.146 155.120 1.00 83.01  ? 232 ASN B CG  1 
ATOM   3015  O OD1 . ASN B 2 210 ? 183.287 134.160 156.339 1.00 83.01  ? 232 ASN B OD1 1 
ATOM   3016  N ND2 . ASN B 2 210 ? 184.656 134.210 154.561 1.00 83.01  ? 232 ASN B ND2 1 
ATOM   3017  N N   . SER B 2 211 ? 180.611 131.841 155.044 1.00 102.24 ? 233 SER B N   1 
ATOM   3018  C CA  . SER B 2 211 ? 180.233 130.585 155.671 1.00 102.24 ? 233 SER B CA  1 
ATOM   3019  C C   . SER B 2 211 ? 181.335 129.556 155.472 1.00 102.24 ? 233 SER B C   1 
ATOM   3020  O O   . SER B 2 211 ? 182.133 129.648 154.535 1.00 102.24 ? 233 SER B O   1 
ATOM   3021  C CB  . SER B 2 211 ? 178.915 130.047 155.102 1.00 102.24 ? 233 SER B CB  1 
ATOM   3022  O OG  . SER B 2 211 ? 179.109 129.488 153.814 1.00 102.24 ? 233 SER B OG  1 
ATOM   3023  N N   . GLU B 2 212 ? 181.371 128.572 156.370 1.00 118.44 ? 234 GLU B N   1 
ATOM   3024  C CA  . GLU B 2 212 ? 182.346 127.493 156.290 1.00 118.44 ? 234 GLU B CA  1 
ATOM   3025  C C   . GLU B 2 212 ? 181.786 126.262 155.588 1.00 118.44 ? 234 GLU B C   1 
ATOM   3026  O O   . GLU B 2 212 ? 182.515 125.578 154.861 1.00 118.44 ? 234 GLU B O   1 
ATOM   3027  C CB  . GLU B 2 212 ? 182.829 127.120 157.695 1.00 118.44 ? 234 GLU B CB  1 
ATOM   3028  C CG  . GLU B 2 212 ? 183.881 126.021 157.732 1.00 118.44 ? 234 GLU B CG  1 
ATOM   3029  C CD  . GLU B 2 212 ? 185.152 126.401 156.998 1.00 118.44 ? 234 GLU B CD  1 
ATOM   3030  O OE1 . GLU B 2 212 ? 185.249 126.114 155.787 1.00 118.44 ? 234 GLU B OE1 1 
ATOM   3031  O OE2 . GLU B 2 212 ? 186.054 126.987 157.633 1.00 118.44 ? 234 GLU B OE2 1 
ATOM   3032  N N   . GLU B 2 213 ? 180.498 125.972 155.784 1.00 121.88 ? 235 GLU B N   1 
ATOM   3033  C CA  . GLU B 2 213 ? 179.897 124.792 155.171 1.00 121.88 ? 235 GLU B CA  1 
ATOM   3034  C C   . GLU B 2 213 ? 179.655 125.010 153.682 1.00 121.88 ? 235 GLU B C   1 
ATOM   3035  O O   . GLU B 2 213 ? 180.195 124.285 152.838 1.00 121.88 ? 235 GLU B O   1 
ATOM   3036  C CB  . GLU B 2 213 ? 178.592 124.441 155.887 1.00 121.88 ? 235 GLU B CB  1 
ATOM   3037  C CG  . GLU B 2 213 ? 178.072 123.046 155.587 1.00 121.88 ? 235 GLU B CG  1 
ATOM   3038  C CD  . GLU B 2 213 ? 176.727 122.776 156.231 1.00 121.88 ? 235 GLU B CD  1 
ATOM   3039  O OE1 . GLU B 2 213 ? 175.763 123.510 155.927 1.00 121.88 ? 235 GLU B OE1 1 
ATOM   3040  O OE2 . GLU B 2 213 ? 176.634 121.832 157.043 1.00 121.88 ? 235 GLU B OE2 1 
ATOM   3041  N N   . LEU B 2 214 ? 178.845 126.006 153.340 1.00 108.00 ? 236 LEU B N   1 
ATOM   3042  C CA  . LEU B 2 214 ? 178.521 126.292 151.952 1.00 108.00 ? 236 LEU B CA  1 
ATOM   3043  C C   . LEU B 2 214 ? 179.483 127.327 151.376 1.00 108.00 ? 236 LEU B C   1 
ATOM   3044  O O   . LEU B 2 214 ? 180.190 128.030 152.101 1.00 108.00 ? 236 LEU B O   1 
ATOM   3045  C CB  . LEU B 2 214 ? 177.080 126.786 151.824 1.00 108.00 ? 236 LEU B CB  1 
ATOM   3046  C CG  . LEU B 2 214 ? 175.989 125.786 152.214 1.00 108.00 ? 236 LEU B CG  1 
ATOM   3047  C CD1 . LEU B 2 214 ? 174.609 126.395 152.025 1.00 108.00 ? 236 LEU B CD1 1 
ATOM   3048  C CD2 . LEU B 2 214 ? 176.128 124.502 151.410 1.00 108.00 ? 236 LEU B CD2 1 
ATOM   3049  N N   . SER B 2 215 ? 179.499 127.410 150.046 1.00 93.88  ? 237 SER B N   1 
ATOM   3050  C CA  . SER B 2 215 ? 180.378 128.319 149.322 1.00 93.88  ? 237 SER B CA  1 
ATOM   3051  C C   . SER B 2 215 ? 179.590 129.264 148.420 1.00 93.88  ? 237 SER B C   1 
ATOM   3052  O O   . SER B 2 215 ? 180.115 129.765 147.424 1.00 93.88  ? 237 SER B O   1 
ATOM   3053  C CB  . SER B 2 215 ? 181.408 127.538 148.507 1.00 93.88  ? 237 SER B CB  1 
ATOM   3054  O OG  . SER B 2 215 ? 180.773 126.685 147.570 1.00 93.88  ? 237 SER B OG  1 
ATOM   3055  N N   . SER B 2 216 ? 178.321 129.515 148.758 1.00 81.51  ? 238 SER B N   1 
ATOM   3056  C CA  . SER B 2 216 ? 177.487 130.379 147.932 1.00 81.51  ? 238 SER B CA  1 
ATOM   3057  C C   . SER B 2 216 ? 176.601 131.305 148.761 1.00 81.51  ? 238 SER B C   1 
ATOM   3058  O O   . SER B 2 216 ? 175.623 131.845 148.230 1.00 81.51  ? 238 SER B O   1 
ATOM   3059  C CB  . SER B 2 216 ? 176.611 129.546 146.993 1.00 81.51  ? 238 SER B CB  1 
ATOM   3060  O OG  . SER B 2 216 ? 177.381 128.988 145.946 1.00 81.51  ? 238 SER B OG  1 
ATOM   3061  N N   . ILE B 2 217 ? 176.908 131.503 150.040 1.00 79.73  ? 239 ILE B N   1 
ATOM   3062  C CA  . ILE B 2 217 ? 176.066 132.302 150.918 1.00 79.73  ? 239 ILE B CA  1 
ATOM   3063  C C   . ILE B 2 217 ? 176.922 133.310 151.670 1.00 79.73  ? 239 ILE B C   1 
ATOM   3064  O O   . ILE B 2 217 ? 178.077 133.042 152.016 1.00 79.73  ? 239 ILE B O   1 
ATOM   3065  C CB  . ILE B 2 217 ? 175.269 131.420 151.903 1.00 79.73  ? 239 ILE B CB  1 
ATOM   3066  C CG1 . ILE B 2 217 ? 176.184 130.396 152.575 1.00 79.73  ? 239 ILE B CG1 1 
ATOM   3067  C CG2 . ILE B 2 217 ? 174.130 130.715 151.185 1.00 79.73  ? 239 ILE B CG2 1 
ATOM   3068  C CD1 . ILE B 2 217 ? 175.566 129.739 153.790 1.00 79.73  ? 239 ILE B CD1 1 
ATOM   3069  N N   . LEU B 2 218 ? 176.341 134.481 151.920 1.00 54.54  ? 240 LEU B N   1 
ATOM   3070  C CA  . LEU B 2 218 ? 176.987 135.543 152.680 1.00 54.54  ? 240 LEU B CA  1 
ATOM   3071  C C   . LEU B 2 218 ? 175.989 136.102 153.679 1.00 54.54  ? 240 LEU B C   1 
ATOM   3072  O O   . LEU B 2 218 ? 174.864 136.448 153.307 1.00 54.54  ? 240 LEU B O   1 
ATOM   3073  C CB  . LEU B 2 218 ? 177.494 136.663 151.763 1.00 54.54  ? 240 LEU B CB  1 
ATOM   3074  C CG  . LEU B 2 218 ? 178.745 136.398 150.925 1.00 54.54  ? 240 LEU B CG  1 
ATOM   3075  C CD1 . LEU B 2 218 ? 179.053 137.603 150.051 1.00 54.54  ? 240 LEU B CD1 1 
ATOM   3076  C CD2 . LEU B 2 218 ? 179.929 136.064 151.816 1.00 54.54  ? 240 LEU B CD2 1 
ATOM   3077  N N   . LYS B 2 219 ? 176.400 136.192 154.941 1.00 56.51  ? 241 LYS B N   1 
ATOM   3078  C CA  . LYS B 2 219 ? 175.540 136.702 156.004 1.00 56.51  ? 241 LYS B CA  1 
ATOM   3079  C C   . LYS B 2 219 ? 175.778 138.200 156.151 1.00 56.51  ? 241 LYS B C   1 
ATOM   3080  O O   . LYS B 2 219 ? 176.821 138.626 156.658 1.00 56.51  ? 241 LYS B O   1 
ATOM   3081  C CB  . LYS B 2 219 ? 175.808 135.966 157.314 1.00 56.51  ? 241 LYS B CB  1 
ATOM   3082  C CG  . LYS B 2 219 ? 175.499 134.479 157.258 1.00 56.51  ? 241 LYS B CG  1 
ATOM   3083  C CD  . LYS B 2 219 ? 175.735 133.813 158.602 1.00 56.51  ? 241 LYS B CD  1 
ATOM   3084  C CE  . LYS B 2 219 ? 175.431 132.326 158.539 1.00 56.51  ? 241 LYS B CE  1 
ATOM   3085  N NZ  . LYS B 2 219 ? 175.645 131.658 159.853 1.00 56.51  ? 241 LYS B NZ  1 
ATOM   3086  N N   . LEU B 2 220 ? 174.812 138.998 155.705 1.00 43.86  ? 242 LEU B N   1 
ATOM   3087  C CA  . LEU B 2 220 ? 174.904 140.448 155.787 1.00 43.86  ? 242 LEU B CA  1 
ATOM   3088  C C   . LEU B 2 220 ? 174.311 140.940 157.100 1.00 43.86  ? 242 LEU B C   1 
ATOM   3089  O O   . LEU B 2 220 ? 173.244 140.486 157.523 1.00 43.86  ? 242 LEU B O   1 
ATOM   3090  C CB  . LEU B 2 220 ? 174.180 141.103 154.609 1.00 43.86  ? 242 LEU B CB  1 
ATOM   3091  C CG  . LEU B 2 220 ? 174.998 141.372 153.343 1.00 43.86  ? 242 LEU B CG  1 
ATOM   3092  C CD1 . LEU B 2 220 ? 176.161 142.304 153.645 1.00 43.86  ? 242 LEU B CD1 1 
ATOM   3093  C CD2 . LEU B 2 220 ? 175.492 140.078 152.710 1.00 43.86  ? 242 LEU B CD2 1 
ATOM   3094  N N   . THR B 2 221 ? 175.013 141.870 157.745 1.00 40.69  ? 243 THR B N   1 
ATOM   3095  C CA  . THR B 2 221 ? 174.566 142.449 159.003 1.00 40.69  ? 243 THR B CA  1 
ATOM   3096  C C   . THR B 2 221 ? 174.789 143.953 158.973 1.00 40.69  ? 243 THR B C   1 
ATOM   3097  O O   . THR B 2 221 ? 175.845 144.424 158.539 1.00 40.69  ? 243 THR B O   1 
ATOM   3098  C CB  . THR B 2 221 ? 175.301 141.837 160.202 1.00 40.69  ? 243 THR B CB  1 
ATOM   3099  O OG1 . THR B 2 221 ? 176.705 141.775 159.922 1.00 40.69  ? 243 THR B OG1 1 
ATOM   3100  C CG2 . THR B 2 221 ? 174.781 140.436 160.492 1.00 40.69  ? 243 THR B CG2 1 
ATOM   3101  N N   . TRP B 2 222 ? 173.793 144.701 159.442 1.00 42.72  ? 244 TRP B N   1 
ATOM   3102  C CA  . TRP B 2 222 ? 173.861 146.154 159.451 1.00 42.72  ? 244 TRP B CA  1 
ATOM   3103  C C   . TRP B 2 222 ? 173.066 146.679 160.638 1.00 42.72  ? 244 TRP B C   1 
ATOM   3104  O O   . TRP B 2 222 ? 172.368 145.931 161.327 1.00 42.72  ? 244 TRP B O   1 
ATOM   3105  C CB  . TRP B 2 222 ? 173.336 146.746 158.139 1.00 42.72  ? 244 TRP B CB  1 
ATOM   3106  C CG  . TRP B 2 222 ? 171.902 146.413 157.865 1.00 42.72  ? 244 TRP B CG  1 
ATOM   3107  C CD1 . TRP B 2 222 ? 170.809 147.151 158.214 1.00 42.72  ? 244 TRP B CD1 1 
ATOM   3108  C CD2 . TRP B 2 222 ? 171.404 145.254 157.186 1.00 42.72  ? 244 TRP B CD2 1 
ATOM   3109  N NE1 . TRP B 2 222 ? 169.661 146.524 157.793 1.00 42.72  ? 244 TRP B NE1 1 
ATOM   3110  C CE2 . TRP B 2 222 ? 170.000 145.357 157.160 1.00 42.72  ? 244 TRP B CE2 1 
ATOM   3111  C CE3 . TRP B 2 222 ? 172.010 144.140 156.598 1.00 42.72  ? 244 TRP B CE3 1 
ATOM   3112  C CZ2 . TRP B 2 222 ? 169.191 144.389 156.568 1.00 42.72  ? 244 TRP B CZ2 1 
ATOM   3113  C CZ3 . TRP B 2 222 ? 171.206 143.180 156.011 1.00 42.72  ? 244 TRP B CZ3 1 
ATOM   3114  C CH2 . TRP B 2 222 ? 169.812 143.311 156.001 1.00 42.72  ? 244 TRP B CH2 1 
ATOM   3115  N N   . THR B 2 223 ? 173.178 147.985 160.867 1.00 50.94  ? 245 THR B N   1 
ATOM   3116  C CA  . THR B 2 223 ? 172.494 148.654 161.964 1.00 50.94  ? 245 THR B CA  1 
ATOM   3117  C C   . THR B 2 223 ? 171.308 149.442 161.424 1.00 50.94  ? 245 THR B C   1 
ATOM   3118  O O   . THR B 2 223 ? 171.457 150.233 160.486 1.00 50.94  ? 245 THR B O   1 
ATOM   3119  C CB  . THR B 2 223 ? 173.446 149.586 162.715 1.00 50.94  ? 245 THR B CB  1 
ATOM   3120  O OG1 . THR B 2 223 ? 174.591 148.847 163.159 1.00 50.94  ? 245 THR B OG1 1 
ATOM   3121  C CG2 . THR B 2 223 ? 172.750 150.201 163.919 1.00 50.94  ? 245 THR B CG2 1 
ATOM   3122  N N   . ASN B 2 224 ? 170.127 149.224 162.022 1.00 31.25  ? 246 ASN B N   1 
ATOM   3123  C CA  . ASN B 2 224 ? 168.921 149.922 161.608 1.00 31.25  ? 246 ASN B CA  1 
ATOM   3124  C C   . ASN B 2 224 ? 168.769 151.235 162.370 1.00 31.25  ? 246 ASN B C   1 
ATOM   3125  O O   . ASN B 2 224 ? 169.203 151.346 163.522 1.00 31.25  ? 246 ASN B O   1 
ATOM   3126  C CB  . ASN B 2 224 ? 167.692 149.049 161.844 1.00 31.25  ? 246 ASN B CB  1 
ATOM   3127  C CG  . ASN B 2 224 ? 167.688 147.804 160.980 1.00 31.25  ? 246 ASN B CG  1 
ATOM   3128  O OD1 . ASN B 2 224 ? 168.737 147.340 160.536 1.00 31.25  ? 246 ASN B OD1 1 
ATOM   3129  N ND2 . ASN B 2 224 ? 166.503 147.258 160.736 1.00 31.25  ? 246 ASN B ND2 1 
ATOM   3130  N N   . PRO B 2 225 ? 168.163 152.244 161.748 1.00 31.39  ? 247 PRO B N   1 
ATOM   3131  C CA  . PRO B 2 225 ? 167.954 153.523 162.435 1.00 31.39  ? 247 PRO B CA  1 
ATOM   3132  C C   . PRO B 2 225 ? 166.997 153.376 163.610 1.00 31.39  ? 247 PRO B C   1 
ATOM   3133  O O   . PRO B 2 225 ? 166.375 152.335 163.829 1.00 31.39  ? 247 PRO B O   1 
ATOM   3134  C CB  . PRO B 2 225 ? 167.367 154.426 161.346 1.00 31.39  ? 247 PRO B CB  1 
ATOM   3135  C CG  . PRO B 2 225 ? 167.755 153.775 160.054 1.00 31.39  ? 247 PRO B CG  1 
ATOM   3136  C CD  . PRO B 2 225 ? 167.757 152.305 160.334 1.00 31.39  ? 247 PRO B CD  1 
ATOM   3137  N N   . SER B 2 226 ? 166.880 154.463 164.373 1.00 33.64  ? 248 SER B N   1 
ATOM   3138  C CA  . SER B 2 226 ? 166.066 154.467 165.582 1.00 33.64  ? 248 SER B CA  1 
ATOM   3139  C C   . SER B 2 226 ? 164.574 154.591 165.303 1.00 33.64  ? 248 SER B C   1 
ATOM   3140  O O   . SER B 2 226 ? 163.777 154.482 166.240 1.00 33.64  ? 248 SER B O   1 
ATOM   3141  C CB  . SER B 2 226 ? 166.508 155.604 166.506 1.00 33.64  ? 248 SER B CB  1 
ATOM   3142  O OG  . SER B 2 226 ? 167.921 155.670 166.592 1.00 33.64  ? 248 SER B OG  1 
ATOM   3143  N N   . ILE B 2 227 ? 164.177 154.813 164.052 1.00 35.16  ? 249 ILE B N   1 
ATOM   3144  C CA  . ILE B 2 227 ? 162.767 154.957 163.710 1.00 35.16  ? 249 ILE B CA  1 
ATOM   3145  C C   . ILE B 2 227 ? 162.211 153.609 163.274 1.00 35.16  ? 249 ILE B C   1 
ATOM   3146  O O   . ILE B 2 227 ? 161.122 153.531 162.695 1.00 35.16  ? 249 ILE B O   1 
ATOM   3147  C CB  . ILE B 2 227 ? 162.563 156.019 162.615 1.00 35.16  ? 249 ILE B CB  1 
ATOM   3148  C CG1 . ILE B 2 227 ? 163.472 155.732 161.418 1.00 35.16  ? 249 ILE B CG1 1 
ATOM   3149  C CG2 . ILE B 2 227 ? 162.822 157.411 163.169 1.00 35.16  ? 249 ILE B CG2 1 
ATOM   3150  C CD1 . ILE B 2 227 ? 163.344 156.740 160.298 1.00 35.16  ? 249 ILE B CD1 1 
ATOM   3151  N N   . LYS B 2 228 ? 162.958 152.537 163.548 1.00 42.90  ? 250 LYS B N   1 
ATOM   3152  C CA  . LYS B 2 228 ? 162.499 151.204 163.173 1.00 42.90  ? 250 LYS B CA  1 
ATOM   3153  C C   . LYS B 2 228 ? 161.305 150.762 164.009 1.00 42.90  ? 250 LYS B C   1 
ATOM   3154  O O   . LYS B 2 228 ? 160.537 149.894 163.579 1.00 42.90  ? 250 LYS B O   1 
ATOM   3155  C CB  . LYS B 2 228 ? 163.641 150.198 163.305 1.00 42.90  ? 250 LYS B CB  1 
ATOM   3156  C CG  . LYS B 2 228 ? 164.180 150.054 164.718 1.00 42.90  ? 250 LYS B CG  1 
ATOM   3157  C CD  . LYS B 2 228 ? 165.282 149.010 164.783 1.00 42.90  ? 250 LYS B CD  1 
ATOM   3158  C CE  . LYS B 2 228 ? 165.799 148.841 166.202 1.00 42.90  ? 250 LYS B CE  1 
ATOM   3159  N NZ  . LYS B 2 228 ? 166.860 147.800 166.283 1.00 42.90  ? 250 LYS B NZ  1 
ATOM   3160  N N   . SER B 2 229 ? 161.134 151.339 165.200 1.00 82.10  ? 251 SER B N   1 
ATOM   3161  C CA  . SER B 2 229 ? 160.011 150.981 166.057 1.00 82.10  ? 251 SER B CA  1 
ATOM   3162  C C   . SER B 2 229 ? 158.751 151.773 165.739 1.00 82.10  ? 251 SER B C   1 
ATOM   3163  O O   . SER B 2 229 ? 157.652 151.326 166.084 1.00 82.10  ? 251 SER B O   1 
ATOM   3164  C CB  . SER B 2 229 ? 160.386 151.185 167.527 1.00 82.10  ? 251 SER B CB  1 
ATOM   3165  O OG  . SER B 2 229 ? 160.717 152.539 167.785 1.00 82.10  ? 251 SER B OG  1 
ATOM   3166  N N   . VAL B 2 230 ? 158.882 152.930 165.093 1.00 39.45  ? 252 VAL B N   1 
ATOM   3167  C CA  . VAL B 2 230 ? 157.716 153.754 164.787 1.00 39.45  ? 252 VAL B CA  1 
ATOM   3168  C C   . VAL B 2 230 ? 156.985 153.217 163.563 1.00 39.45  ? 252 VAL B C   1 
ATOM   3169  O O   . VAL B 2 230 ? 155.782 152.936 163.610 1.00 39.45  ? 252 VAL B O   1 
ATOM   3170  C CB  . VAL B 2 230 ? 158.132 155.223 164.593 1.00 39.45  ? 252 VAL B CB  1 
ATOM   3171  C CG1 . VAL B 2 230 ? 156.909 156.092 164.346 1.00 39.45  ? 252 VAL B CG1 1 
ATOM   3172  C CG2 . VAL B 2 230 ? 158.910 155.717 165.802 1.00 39.45  ? 252 VAL B CG2 1 
ATOM   3173  N N   . ILE B 2 231 ? 157.701 153.067 162.451 1.00 32.32  ? 253 ILE B N   1 
ATOM   3174  C CA  . ILE B 2 231 ? 157.111 152.628 161.194 1.00 32.32  ? 253 ILE B CA  1 
ATOM   3175  C C   . ILE B 2 231 ? 157.937 151.487 160.620 1.00 32.32  ? 253 ILE B C   1 
ATOM   3176  O O   . ILE B 2 231 ? 159.142 151.378 160.867 1.00 32.32  ? 253 ILE B O   1 
ATOM   3177  C CB  . ILE B 2 231 ? 157.010 153.783 160.173 1.00 32.32  ? 253 ILE B CB  1 
ATOM   3178  C CG1 . ILE B 2 231 ? 158.368 154.471 160.015 1.00 32.32  ? 253 ILE B CG1 1 
ATOM   3179  C CG2 . ILE B 2 231 ? 155.941 154.778 160.597 1.00 32.32  ? 253 ILE B CG2 1 
ATOM   3180  C CD1 . ILE B 2 231 ? 158.367 155.599 159.009 1.00 32.32  ? 253 ILE B CD1 1 
ATOM   3181  N N   . ILE B 2 232 ? 157.275 150.633 159.846 1.00 34.05  ? 254 ILE B N   1 
ATOM   3182  C CA  . ILE B 2 232 ? 157.942 149.524 159.177 1.00 34.05  ? 254 ILE B CA  1 
ATOM   3183  C C   . ILE B 2 232 ? 158.650 150.046 157.935 1.00 34.05  ? 254 ILE B C   1 
ATOM   3184  O O   . ILE B 2 232 ? 158.099 150.857 157.180 1.00 34.05  ? 254 ILE B O   1 
ATOM   3185  C CB  . ILE B 2 232 ? 156.932 148.418 158.825 1.00 34.05  ? 254 ILE B CB  1 
ATOM   3186  C CG1 . ILE B 2 232 ? 155.996 148.159 160.008 1.00 34.05  ? 254 ILE B CG1 1 
ATOM   3187  C CG2 . ILE B 2 232 ? 157.654 147.142 158.427 1.00 34.05  ? 254 ILE B CG2 1 
ATOM   3188  C CD1 . ILE B 2 232 ? 154.937 147.117 159.731 1.00 34.05  ? 254 ILE B CD1 1 
ATOM   3189  N N   . LEU B 2 233 ? 159.876 149.581 157.716 1.00 31.58  ? 255 LEU B N   1 
ATOM   3190  C CA  . LEU B 2 233 ? 160.708 150.060 156.623 1.00 31.58  ? 255 LEU B CA  1 
ATOM   3191  C C   . LEU B 2 233 ? 161.198 148.886 155.789 1.00 31.58  ? 255 LEU B C   1 
ATOM   3192  O O   . LEU B 2 233 ? 161.294 147.754 156.272 1.00 31.58  ? 255 LEU B O   1 
ATOM   3193  C CB  . LEU B 2 233 ? 161.906 150.874 157.144 1.00 31.58  ? 255 LEU B CB  1 
ATOM   3194  C CG  . LEU B 2 233 ? 163.073 150.135 157.805 1.00 31.58  ? 255 LEU B CG  1 
ATOM   3195  C CD1 . LEU B 2 233 ? 164.301 151.028 157.853 1.00 31.58  ? 255 LEU B CD1 1 
ATOM   3196  C CD2 . LEU B 2 233 ? 162.712 149.663 159.205 1.00 31.58  ? 255 LEU B CD2 1 
ATOM   3197  N N   . LYS B 2 234 ? 161.505 149.169 154.526 1.00 39.84  ? 256 LYS B N   1 
ATOM   3198  C CA  . LYS B 2 234 ? 162.024 148.184 153.590 1.00 39.84  ? 256 LYS B CA  1 
ATOM   3199  C C   . LYS B 2 234 ? 163.453 148.547 153.205 1.00 39.84  ? 256 LYS B C   1 
ATOM   3200  O O   . LYS B 2 234 ? 163.972 149.605 153.572 1.00 39.84  ? 256 LYS B O   1 
ATOM   3201  C CB  . LYS B 2 234 ? 161.140 148.087 152.340 1.00 39.84  ? 256 LYS B CB  1 
ATOM   3202  C CG  . LYS B 2 234 ? 160.931 149.407 151.619 1.00 39.84  ? 256 LYS B CG  1 
ATOM   3203  C CD  . LYS B 2 234 ? 159.996 149.239 150.433 1.00 39.84  ? 256 LYS B CD  1 
ATOM   3204  C CE  . LYS B 2 234 ? 159.711 150.571 149.760 1.00 39.84  ? 256 LYS B CE  1 
ATOM   3205  N NZ  . LYS B 2 234 ? 158.778 150.421 148.609 1.00 39.84  ? 256 LYS B NZ  1 
ATOM   3206  N N   . TYR B 2 235 ? 164.092 147.653 152.453 1.00 38.88  ? 257 TYR B N   1 
ATOM   3207  C CA  . TYR B 2 235 ? 165.492 147.811 152.093 1.00 38.88  ? 257 TYR B CA  1 
ATOM   3208  C C   . TYR B 2 235 ? 165.698 147.437 150.632 1.00 38.88  ? 257 TYR B C   1 
ATOM   3209  O O   . TYR B 2 235 ? 164.888 146.732 150.026 1.00 38.88  ? 257 TYR B O   1 
ATOM   3210  C CB  . TYR B 2 235 ? 166.405 146.951 152.978 1.00 38.88  ? 257 TYR B CB  1 
ATOM   3211  C CG  . TYR B 2 235 ? 166.100 147.037 154.456 1.00 38.88  ? 257 TYR B CG  1 
ATOM   3212  C CD1 . TYR B 2 235 ? 166.673 148.023 155.247 1.00 38.88  ? 257 TYR B CD1 1 
ATOM   3213  C CD2 . TYR B 2 235 ? 165.243 146.127 155.062 1.00 38.88  ? 257 TYR B CD2 1 
ATOM   3214  C CE1 . TYR B 2 235 ? 166.399 148.103 156.599 1.00 38.88  ? 257 TYR B CE1 1 
ATOM   3215  C CE2 . TYR B 2 235 ? 164.963 146.199 156.412 1.00 38.88  ? 257 TYR B CE2 1 
ATOM   3216  C CZ  . TYR B 2 235 ? 165.543 147.189 157.176 1.00 38.88  ? 257 TYR B CZ  1 
ATOM   3217  O OH  . TYR B 2 235 ? 165.266 147.263 158.522 1.00 38.88  ? 257 TYR B OH  1 
ATOM   3218  N N   . ASN B 2 236 ? 166.805 147.924 150.073 1.00 45.36  ? 258 ASN B N   1 
ATOM   3219  C CA  . ASN B 2 236 ? 167.229 147.585 148.720 1.00 45.36  ? 258 ASN B CA  1 
ATOM   3220  C C   . ASN B 2 236 ? 168.721 147.295 148.744 1.00 45.36  ? 258 ASN B C   1 
ATOM   3221  O O   . ASN B 2 236 ? 169.524 148.190 149.029 1.00 45.36  ? 258 ASN B O   1 
ATOM   3222  C CB  . ASN B 2 236 ? 166.916 148.715 147.736 1.00 45.36  ? 258 ASN B CB  1 
ATOM   3223  C CG  . ASN B 2 236 ? 165.469 148.713 147.292 1.00 45.36  ? 258 ASN B CG  1 
ATOM   3224  O OD1 . ASN B 2 236 ? 164.868 149.768 147.091 1.00 45.36  ? 258 ASN B OD1 1 
ATOM   3225  N ND2 . ASN B 2 236 ? 164.899 147.524 147.139 1.00 45.36  ? 258 ASN B ND2 1 
ATOM   3226  N N   . ILE B 2 237 ? 169.089 146.054 148.444 1.00 45.74  ? 259 ILE B N   1 
ATOM   3227  C CA  . ILE B 2 237 ? 170.474 145.604 148.502 1.00 45.74  ? 259 ILE B CA  1 
ATOM   3228  C C   . ILE B 2 237 ? 171.004 145.487 147.081 1.00 45.74  ? 259 ILE B C   1 
ATOM   3229  O O   . ILE B 2 237 ? 170.479 144.710 146.274 1.00 45.74  ? 259 ILE B O   1 
ATOM   3230  C CB  . ILE B 2 237 ? 170.598 144.266 149.248 1.00 45.74  ? 259 ILE B CB  1 
ATOM   3231  C CG1 . ILE B 2 237 ? 170.013 144.387 150.657 1.00 45.74  ? 259 ILE B CG1 1 
ATOM   3232  C CG2 . ILE B 2 237 ? 172.051 143.822 149.304 1.00 45.74  ? 259 ILE B CG2 1 
ATOM   3233  C CD1 . ILE B 2 237 ? 170.010 143.088 151.431 1.00 45.74  ? 259 ILE B CD1 1 
ATOM   3234  N N   . GLN B 2 238 ? 172.043 146.258 146.773 1.00 63.45  ? 260 GLN B N   1 
ATOM   3235  C CA  . GLN B 2 238 ? 172.703 146.219 145.474 1.00 63.45  ? 260 GLN B CA  1 
ATOM   3236  C C   . GLN B 2 238 ? 174.095 145.632 145.655 1.00 63.45  ? 260 GLN B C   1 
ATOM   3237  O O   . GLN B 2 238 ? 174.912 146.181 146.402 1.00 63.45  ? 260 GLN B O   1 
ATOM   3238  C CB  . GLN B 2 238 ? 172.779 147.613 144.853 1.00 63.45  ? 260 GLN B CB  1 
ATOM   3239  C CG  . GLN B 2 238 ? 171.429 148.183 144.449 1.00 63.45  ? 260 GLN B CG  1 
ATOM   3240  C CD  . GLN B 2 238 ? 171.554 149.457 143.637 1.00 63.45  ? 260 GLN B CD  1 
ATOM   3241  O OE1 . GLN B 2 238 ? 172.657 149.945 143.391 1.00 63.45  ? 260 GLN B OE1 1 
ATOM   3242  N NE2 . GLN B 2 238 ? 170.419 150.004 143.216 1.00 63.45  ? 260 GLN B NE2 1 
ATOM   3243  N N   . TYR B 2 239 ? 174.361 144.522 144.973 1.00 60.15  ? 261 TYR B N   1 
ATOM   3244  C CA  . TYR B 2 239 ? 175.634 143.826 145.070 1.00 60.15  ? 261 TYR B CA  1 
ATOM   3245  C C   . TYR B 2 239 ? 176.276 143.722 143.694 1.00 60.15  ? 261 TYR B C   1 
ATOM   3246  O O   . TYR B 2 239 ? 175.593 143.753 142.666 1.00 60.15  ? 261 TYR B O   1 
ATOM   3247  C CB  . TYR B 2 239 ? 175.460 142.424 145.670 1.00 60.15  ? 261 TYR B CB  1 
ATOM   3248  C CG  . TYR B 2 239 ? 174.774 141.438 144.750 1.00 60.15  ? 261 TYR B CG  1 
ATOM   3249  C CD1 . TYR B 2 239 ? 173.396 141.456 144.584 1.00 60.15  ? 261 TYR B CD1 1 
ATOM   3250  C CD2 . TYR B 2 239 ? 175.505 140.485 144.052 1.00 60.15  ? 261 TYR B CD2 1 
ATOM   3251  C CE1 . TYR B 2 239 ? 172.765 140.556 143.746 1.00 60.15  ? 261 TYR B CE1 1 
ATOM   3252  C CE2 . TYR B 2 239 ? 174.883 139.582 143.212 1.00 60.15  ? 261 TYR B CE2 1 
ATOM   3253  C CZ  . TYR B 2 239 ? 173.513 139.622 143.063 1.00 60.15  ? 261 TYR B CZ  1 
ATOM   3254  O OH  . TYR B 2 239 ? 172.888 138.724 142.227 1.00 60.15  ? 261 TYR B OH  1 
ATOM   3255  N N   . ARG B 2 240 ? 177.600 143.597 143.687 1.00 101.42 ? 262 ARG B N   1 
ATOM   3256  C CA  . ARG B 2 240 ? 178.352 143.477 142.447 1.00 101.42 ? 262 ARG B CA  1 
ATOM   3257  C C   . ARG B 2 240 ? 179.699 142.843 142.753 1.00 101.42 ? 262 ARG B C   1 
ATOM   3258  O O   . ARG B 2 240 ? 180.126 142.775 143.908 1.00 101.42 ? 262 ARG B O   1 
ATOM   3259  C CB  . ARG B 2 240 ? 178.538 144.836 141.765 1.00 101.42 ? 262 ARG B CB  1 
ATOM   3260  C CG  . ARG B 2 240 ? 179.500 145.764 142.488 1.00 101.42 ? 262 ARG B CG  1 
ATOM   3261  C CD  . ARG B 2 240 ? 179.955 146.897 141.585 1.00 101.42 ? 262 ARG B CD  1 
ATOM   3262  N NE  . ARG B 2 240 ? 180.951 147.745 142.234 1.00 101.42 ? 262 ARG B NE  1 
ATOM   3263  C CZ  . ARG B 2 240 ? 182.258 147.510 142.216 1.00 101.42 ? 262 ARG B CZ  1 
ATOM   3264  N NH1 . ARG B 2 240 ? 182.734 146.448 141.580 1.00 101.42 ? 262 ARG B NH1 1 
ATOM   3265  N NH2 . ARG B 2 240 ? 183.091 148.336 142.834 1.00 101.42 ? 262 ARG B NH2 1 
ATOM   3266  N N   . THR B 2 241 ? 180.364 142.382 141.697 1.00 136.75 ? 263 THR B N   1 
ATOM   3267  C CA  . THR B 2 241 ? 181.680 141.780 141.834 1.00 136.75 ? 263 THR B CA  1 
ATOM   3268  C C   . THR B 2 241 ? 182.751 142.868 141.886 1.00 136.75 ? 263 THR B C   1 
ATOM   3269  O O   . THR B 2 241 ? 182.464 144.067 141.830 1.00 136.75 ? 263 THR B O   1 
ATOM   3270  C CB  . THR B 2 241 ? 181.943 140.808 140.686 1.00 136.75 ? 263 THR B CB  1 
ATOM   3271  O OG1 . THR B 2 241 ? 182.241 141.545 139.494 1.00 136.75 ? 263 THR B OG1 1 
ATOM   3272  C CG2 . THR B 2 241 ? 180.722 139.936 140.438 1.00 136.75 ? 263 THR B CG2 1 
ATOM   3273  N N   . LYS B 2 242 ? 184.009 142.444 141.995 1.00 154.92 ? 264 LYS B N   1 
ATOM   3274  C CA  . LYS B 2 242 ? 185.121 143.384 142.041 1.00 154.92 ? 264 LYS B CA  1 
ATOM   3275  C C   . LYS B 2 242 ? 185.601 143.797 140.657 1.00 154.92 ? 264 LYS B C   1 
ATOM   3276  O O   . LYS B 2 242 ? 186.109 144.913 140.494 1.00 154.92 ? 264 LYS B O   1 
ATOM   3277  C CB  . LYS B 2 242 ? 186.290 142.784 142.827 1.00 154.92 ? 264 LYS B CB  1 
ATOM   3278  C CG  . LYS B 2 242 ? 186.023 142.637 144.316 1.00 154.92 ? 264 LYS B CG  1 
ATOM   3279  C CD  . LYS B 2 242 ? 185.764 143.986 144.967 1.00 154.92 ? 264 LYS B CD  1 
ATOM   3280  C CE  . LYS B 2 242 ? 186.975 144.898 144.854 1.00 154.92 ? 264 LYS B CE  1 
ATOM   3281  N NZ  . LYS B 2 242 ? 188.177 144.305 145.502 1.00 154.92 ? 264 LYS B NZ  1 
ATOM   3282  N N   . ASP B 2 243 ? 185.454 142.928 139.658 1.00 213.87 ? 265 ASP B N   1 
ATOM   3283  C CA  . ASP B 2 243 ? 185.883 143.248 138.303 1.00 213.87 ? 265 ASP B CA  1 
ATOM   3284  C C   . ASP B 2 243 ? 184.810 143.966 137.498 1.00 213.87 ? 265 ASP B C   1 
ATOM   3285  O O   . ASP B 2 243 ? 185.141 144.783 136.630 1.00 213.87 ? 265 ASP B O   1 
ATOM   3286  C CB  . ASP B 2 243 ? 186.305 141.972 137.568 1.00 213.87 ? 265 ASP B CB  1 
ATOM   3287  C CG  . ASP B 2 243 ? 185.296 140.851 137.719 1.00 213.87 ? 265 ASP B CG  1 
ATOM   3288  O OD1 . ASP B 2 243 ? 184.308 141.036 138.460 1.00 213.87 ? 265 ASP B OD1 1 
ATOM   3289  O OD2 . ASP B 2 243 ? 185.491 139.785 137.098 1.00 213.87 ? 265 ASP B OD2 1 
ATOM   3290  N N   . ALA B 2 244 ? 183.538 143.686 137.763 1.00 205.81 ? 266 ALA B N   1 
ATOM   3291  C CA  . ALA B 2 244 ? 182.432 144.313 137.056 1.00 205.81 ? 266 ALA B CA  1 
ATOM   3292  C C   . ALA B 2 244 ? 181.913 145.507 137.846 1.00 205.81 ? 266 ALA B C   1 
ATOM   3293  O O   . ALA B 2 244 ? 181.809 145.455 139.075 1.00 205.81 ? 266 ALA B O   1 
ATOM   3294  C CB  . ALA B 2 244 ? 181.299 143.314 136.814 1.00 205.81 ? 266 ALA B CB  1 
ATOM   3295  N N   . SER B 2 245 ? 181.590 146.583 137.131 1.00 177.46 ? 267 SER B N   1 
ATOM   3296  C CA  . SER B 2 245 ? 181.067 147.793 137.749 1.00 177.46 ? 267 SER B CA  1 
ATOM   3297  C C   . SER B 2 245 ? 179.545 147.837 137.785 1.00 177.46 ? 267 SER B C   1 
ATOM   3298  O O   . SER B 2 245 ? 178.983 148.661 138.515 1.00 177.46 ? 267 SER B O   1 
ATOM   3299  C CB  . SER B 2 245 ? 181.592 149.032 137.015 1.00 177.46 ? 267 SER B CB  1 
ATOM   3300  O OG  . SER B 2 245 ? 180.760 150.154 137.251 1.00 177.46 ? 267 SER B OG  1 
ATOM   3301  N N   . THR B 2 246 ? 178.870 146.982 137.020 1.00 152.16 ? 268 THR B N   1 
ATOM   3302  C CA  . THR B 2 246 ? 177.414 146.966 137.019 1.00 152.16 ? 268 THR B CA  1 
ATOM   3303  C C   . THR B 2 246 ? 176.893 146.442 138.351 1.00 152.16 ? 268 THR B C   1 
ATOM   3304  O O   . THR B 2 246 ? 177.319 145.384 138.825 1.00 152.16 ? 268 THR B O   1 
ATOM   3305  C CB  . THR B 2 246 ? 176.891 146.103 135.872 1.00 152.16 ? 268 THR B CB  1 
ATOM   3306  O OG1 . THR B 2 246 ? 177.660 144.896 135.791 1.00 152.16 ? 268 THR B OG1 1 
ATOM   3307  C CG2 . THR B 2 246 ? 176.995 146.854 134.552 1.00 152.16 ? 268 THR B CG2 1 
ATOM   3308  N N   . TRP B 2 247 ? 175.967 147.183 138.953 1.00 87.83  ? 269 TRP B N   1 
ATOM   3309  C CA  . TRP B 2 247 ? 175.414 146.832 140.255 1.00 87.83  ? 269 TRP B CA  1 
ATOM   3310  C C   . TRP B 2 247 ? 174.147 146.007 140.066 1.00 87.83  ? 269 TRP B C   1 
ATOM   3311  O O   . TRP B 2 247 ? 173.176 146.480 139.465 1.00 87.83  ? 269 TRP B O   1 
ATOM   3312  C CB  . TRP B 2 247 ? 175.119 148.089 141.071 1.00 87.83  ? 269 TRP B CB  1 
ATOM   3313  C CG  . TRP B 2 247 ? 176.345 148.771 141.589 1.00 87.83  ? 269 TRP B CG  1 
ATOM   3314  C CD1 . TRP B 2 247 ? 177.141 149.651 140.916 1.00 87.83  ? 269 TRP B CD1 1 
ATOM   3315  C CD2 . TRP B 2 247 ? 176.917 148.632 142.895 1.00 87.83  ? 269 TRP B CD2 1 
ATOM   3316  N NE1 . TRP B 2 247 ? 178.173 150.068 141.720 1.00 87.83  ? 269 TRP B NE1 1 
ATOM   3317  C CE2 . TRP B 2 247 ? 178.058 149.457 142.941 1.00 87.83  ? 269 TRP B CE2 1 
ATOM   3318  C CE3 . TRP B 2 247 ? 176.576 147.889 144.030 1.00 87.83  ? 269 TRP B CE3 1 
ATOM   3319  C CZ2 . TRP B 2 247 ? 178.860 149.559 144.076 1.00 87.83  ? 269 TRP B CZ2 1 
ATOM   3320  C CZ3 . TRP B 2 247 ? 177.372 147.993 145.155 1.00 87.83  ? 269 TRP B CZ3 1 
ATOM   3321  C CH2 . TRP B 2 247 ? 178.501 148.822 145.170 1.00 87.83  ? 269 TRP B CH2 1 
ATOM   3322  N N   . SER B 2 248 ? 174.159 144.780 140.577 1.00 70.74  ? 270 SER B N   1 
ATOM   3323  C CA  . SER B 2 248 ? 172.984 143.920 140.553 1.00 70.74  ? 270 SER B CA  1 
ATOM   3324  C C   . SER B 2 248 ? 172.145 144.182 141.796 1.00 70.74  ? 270 SER B C   1 
ATOM   3325  O O   . SER B 2 248 ? 172.662 144.157 142.918 1.00 70.74  ? 270 SER B O   1 
ATOM   3326  C CB  . SER B 2 248 ? 173.391 142.448 140.484 1.00 70.74  ? 270 SER B CB  1 
ATOM   3327  O OG  . SER B 2 248 ? 174.449 142.169 141.385 1.00 70.74  ? 270 SER B OG  1 
ATOM   3328  N N   . GLN B 2 249 ? 170.856 144.434 141.595 1.00 52.81  ? 271 GLN B N   1 
ATOM   3329  C CA  . GLN B 2 249 ? 169.955 144.809 142.676 1.00 52.81  ? 271 GLN B CA  1 
ATOM   3330  C C   . GLN B 2 249 ? 169.109 143.613 143.092 1.00 52.81  ? 271 GLN B C   1 
ATOM   3331  O O   . GLN B 2 249 ? 168.543 142.919 142.241 1.00 52.81  ? 271 GLN B O   1 
ATOM   3332  C CB  . GLN B 2 249 ? 169.054 145.970 142.254 1.00 52.81  ? 271 GLN B CB  1 
ATOM   3333  C CG  . GLN B 2 249 ? 168.005 146.347 143.286 1.00 52.81  ? 271 GLN B CG  1 
ATOM   3334  C CD  . GLN B 2 249 ? 167.212 147.575 142.888 1.00 52.81  ? 271 GLN B CD  1 
ATOM   3335  O OE1 . GLN B 2 249 ? 167.723 148.466 142.210 1.00 52.81  ? 271 GLN B OE1 1 
ATOM   3336  N NE2 . GLN B 2 249 ? 165.953 147.628 143.309 1.00 52.81  ? 271 GLN B NE2 1 
ATOM   3337  N N   . ILE B 2 250 ? 169.031 143.379 144.395 1.00 48.52  ? 272 ILE B N   1 
ATOM   3338  C CA  . ILE B 2 250 ? 168.164 142.320 144.924 1.00 48.52  ? 272 ILE B CA  1 
ATOM   3339  C C   . ILE B 2 250 ? 166.712 142.768 144.819 1.00 48.52  ? 272 ILE B C   1 
ATOM   3340  O O   . ILE B 2 250 ? 166.407 143.935 145.124 1.00 48.52  ? 272 ILE B O   1 
ATOM   3341  C CB  . ILE B 2 250 ? 168.544 142.001 146.373 1.00 48.52  ? 272 ILE B CB  1 
ATOM   3342  C CG1 . ILE B 2 250 ? 169.894 141.283 146.422 1.00 48.52  ? 272 ILE B CG1 1 
ATOM   3343  C CG2 . ILE B 2 250 ? 167.466 141.165 147.052 1.00 48.52  ? 272 ILE B CG2 1 
ATOM   3344  C CD1 . ILE B 2 250 ? 169.877 139.911 145.785 1.00 48.52  ? 272 ILE B CD1 1 
ATOM   3345  N N   . PRO B 2 251 ? 165.796 141.908 144.378 1.00 53.73  ? 273 PRO B N   1 
ATOM   3346  C CA  . PRO B 2 251 ? 164.383 142.297 144.295 1.00 53.73  ? 273 PRO B CA  1 
ATOM   3347  C C   . PRO B 2 251 ? 163.855 142.738 145.648 1.00 53.73  ? 273 PRO B C   1 
ATOM   3348  O O   . PRO B 2 251 ? 164.119 142.089 146.671 1.00 53.73  ? 273 PRO B O   1 
ATOM   3349  C CB  . PRO B 2 251 ? 163.691 141.011 143.818 1.00 53.73  ? 273 PRO B CB  1 
ATOM   3350  C CG  . PRO B 2 251 ? 164.757 140.259 143.100 1.00 53.73  ? 273 PRO B CG  1 
ATOM   3351  C CD  . PRO B 2 251 ? 166.034 140.562 143.830 1.00 53.73  ? 273 PRO B CD  1 
ATOM   3352  N N   . PRO B 2 252 ? 163.106 143.844 145.695 1.00 60.02  ? 274 PRO B N   1 
ATOM   3353  C CA  . PRO B 2 252 ? 162.603 144.346 146.985 1.00 60.02  ? 274 PRO B CA  1 
ATOM   3354  C C   . PRO B 2 252 ? 161.547 143.459 147.625 1.00 60.02  ? 274 PRO B C   1 
ATOM   3355  O O   . PRO B 2 252 ? 161.150 143.734 148.765 1.00 60.02  ? 274 PRO B O   1 
ATOM   3356  C CB  . PRO B 2 252 ? 162.020 145.722 146.627 1.00 60.02  ? 274 PRO B CB  1 
ATOM   3357  C CG  . PRO B 2 252 ? 162.577 146.054 145.271 1.00 60.02  ? 274 PRO B CG  1 
ATOM   3358  C CD  . PRO B 2 252 ? 162.765 144.744 144.582 1.00 60.02  ? 274 PRO B CD  1 
ATOM   3359  N N   . GLU B 2 253 ? 161.078 142.416 146.937 1.00 82.59  ? 275 GLU B N   1 
ATOM   3360  C CA  . GLU B 2 253 ? 160.053 141.551 147.511 1.00 82.59  ? 275 GLU B CA  1 
ATOM   3361  C C   . GLU B 2 253 ? 160.585 140.752 148.695 1.00 82.59  ? 275 GLU B C   1 
ATOM   3362  O O   . GLU B 2 253 ? 159.802 140.311 149.544 1.00 82.59  ? 275 GLU B O   1 
ATOM   3363  C CB  . GLU B 2 253 ? 159.499 140.610 146.442 1.00 82.59  ? 275 GLU B CB  1 
ATOM   3364  C CG  . GLU B 2 253 ? 158.564 141.280 145.446 1.00 82.59  ? 275 GLU B CG  1 
ATOM   3365  C CD  . GLU B 2 253 ? 159.302 142.113 144.416 1.00 82.59  ? 275 GLU B CD  1 
ATOM   3366  O OE1 . GLU B 2 253 ? 160.534 141.951 144.288 1.00 82.59  ? 275 GLU B OE1 1 
ATOM   3367  O OE2 . GLU B 2 253 ? 158.651 142.932 143.734 1.00 82.59  ? 275 GLU B OE2 1 
ATOM   3368  N N   . ASP B 2 254 ? 161.900 140.554 148.769 1.00 75.35  ? 276 ASP B N   1 
ATOM   3369  C CA  . ASP B 2 254 ? 162.501 139.811 149.869 1.00 75.35  ? 276 ASP B CA  1 
ATOM   3370  C C   . ASP B 2 254 ? 162.940 140.700 151.023 1.00 75.35  ? 276 ASP B C   1 
ATOM   3371  O O   . ASP B 2 254 ? 163.217 140.183 152.112 1.00 75.35  ? 276 ASP B O   1 
ATOM   3372  C CB  . ASP B 2 254 ? 163.702 139.004 149.366 1.00 75.35  ? 276 ASP B CB  1 
ATOM   3373  C CG  . ASP B 2 254 ? 163.324 138.012 148.284 1.00 75.35  ? 276 ASP B CG  1 
ATOM   3374  O OD1 . ASP B 2 254 ? 162.177 137.519 148.302 1.00 75.35  ? 276 ASP B OD1 1 
ATOM   3375  O OD2 . ASP B 2 254 ? 164.174 137.727 147.414 1.00 75.35  ? 276 ASP B OD2 1 
ATOM   3376  N N   . THR B 2 255 ? 163.011 142.015 150.817 1.00 58.18  ? 277 THR B N   1 
ATOM   3377  C CA  . THR B 2 255 ? 163.438 142.952 151.850 1.00 58.18  ? 277 THR B CA  1 
ATOM   3378  C C   . THR B 2 255 ? 162.351 143.977 152.158 1.00 58.18  ? 277 THR B C   1 
ATOM   3379  O O   . THR B 2 255 ? 162.647 145.119 152.516 1.00 58.18  ? 277 THR B O   1 
ATOM   3380  C CB  . THR B 2 255 ? 164.732 143.656 151.442 1.00 58.18  ? 277 THR B CB  1 
ATOM   3381  O OG1 . THR B 2 255 ? 164.525 144.373 150.219 1.00 58.18  ? 277 THR B OG1 1 
ATOM   3382  C CG2 . THR B 2 255 ? 165.851 142.644 151.245 1.00 58.18  ? 277 THR B CG2 1 
ATOM   3383  N N   . ALA B 2 256 ? 161.087 143.582 152.024 1.00 51.90  ? 278 ALA B N   1 
ATOM   3384  C CA  . ALA B 2 256 ? 159.958 144.470 152.259 1.00 51.90  ? 278 ALA B CA  1 
ATOM   3385  C C   . ALA B 2 256 ? 159.506 144.486 153.715 1.00 51.90  ? 278 ALA B C   1 
ATOM   3386  O O   . ALA B 2 256 ? 158.430 145.016 154.010 1.00 51.90  ? 278 ALA B O   1 
ATOM   3387  C CB  . ALA B 2 256 ? 158.785 144.081 151.356 1.00 51.90  ? 278 ALA B CB  1 
ATOM   3388  N N   . SER B 2 257 ? 160.292 143.917 154.625 1.00 41.59  ? 279 SER B N   1 
ATOM   3389  C CA  . SER B 2 257 ? 159.952 143.884 156.039 1.00 41.59  ? 279 SER B CA  1 
ATOM   3390  C C   . SER B 2 257 ? 161.135 144.372 156.862 1.00 41.59  ? 279 SER B C   1 
ATOM   3391  O O   . SER B 2 257 ? 162.268 144.445 156.379 1.00 41.59  ? 279 SER B O   1 
ATOM   3392  C CB  . SER B 2 257 ? 159.545 142.473 156.487 1.00 41.59  ? 279 SER B CB  1 
ATOM   3393  O OG  . SER B 2 257 ? 160.603 141.552 156.290 1.00 41.59  ? 279 SER B OG  1 
ATOM   3394  N N   . THR B 2 258 ? 160.855 144.709 158.118 1.00 36.78  ? 280 THR B N   1 
ATOM   3395  C CA  . THR B 2 258 ? 161.897 145.167 159.029 1.00 36.78  ? 280 THR B CA  1 
ATOM   3396  C C   . THR B 2 258 ? 162.827 144.009 159.372 1.00 36.78  ? 280 THR B C   1 
ATOM   3397  O O   . THR B 2 258 ? 162.406 143.027 159.991 1.00 36.78  ? 280 THR B O   1 
ATOM   3398  C CB  . THR B 2 258 ? 161.277 145.749 160.297 1.00 36.78  ? 280 THR B CB  1 
ATOM   3399  O OG1 . THR B 2 258 ? 160.544 146.936 159.971 1.00 36.78  ? 280 THR B OG1 1 
ATOM   3400  C CG2 . THR B 2 258 ? 162.360 146.091 161.309 1.00 36.78  ? 280 THR B CG2 1 
ATOM   3401  N N   . ARG B 2 259 ? 164.090 144.124 158.968 1.00 41.81  ? 281 ARG B N   1 
ATOM   3402  C CA  . ARG B 2 259 ? 165.066 143.072 159.213 1.00 41.81  ? 281 ARG B CA  1 
ATOM   3403  C C   . ARG B 2 259 ? 166.457 143.685 159.227 1.00 41.81  ? 281 ARG B C   1 
ATOM   3404  O O   . ARG B 2 259 ? 166.686 144.764 158.674 1.00 41.81  ? 281 ARG B O   1 
ATOM   3405  C CB  . ARG B 2 259 ? 164.975 141.965 158.157 1.00 41.81  ? 281 ARG B CB  1 
ATOM   3406  C CG  . ARG B 2 259 ? 165.312 142.429 156.749 1.00 41.81  ? 281 ARG B CG  1 
ATOM   3407  C CD  . ARG B 2 259 ? 164.737 141.489 155.704 1.00 41.81  ? 281 ARG B CD  1 
ATOM   3408  N NE  . ARG B 2 259 ? 165.166 140.110 155.917 1.00 41.81  ? 281 ARG B NE  1 
ATOM   3409  C CZ  . ARG B 2 259 ? 164.760 139.081 155.181 1.00 41.81  ? 281 ARG B CZ  1 
ATOM   3410  N NH1 . ARG B 2 259 ? 163.911 139.273 154.182 1.00 41.81  ? 281 ARG B NH1 1 
ATOM   3411  N NH2 . ARG B 2 259 ? 165.203 137.859 155.445 1.00 41.81  ? 281 ARG B NH2 1 
ATOM   3412  N N   . SER B 2 260 ? 167.386 142.978 159.873 1.00 36.93  ? 282 SER B N   1 
ATOM   3413  C CA  . SER B 2 260 ? 168.777 143.407 159.954 1.00 36.93  ? 282 SER B CA  1 
ATOM   3414  C C   . SER B 2 260 ? 169.734 142.348 159.419 1.00 36.93  ? 282 SER B C   1 
ATOM   3415  O O   . SER B 2 260 ? 170.940 142.419 159.679 1.00 36.93  ? 282 SER B O   1 
ATOM   3416  C CB  . SER B 2 260 ? 169.144 143.773 161.393 1.00 36.93  ? 282 SER B CB  1 
ATOM   3417  O OG  . SER B 2 260 ? 170.488 144.217 161.478 1.00 36.93  ? 282 SER B OG  1 
ATOM   3418  N N   . SER B 2 261 ? 169.225 141.367 158.678 1.00 40.18  ? 283 SER B N   1 
ATOM   3419  C CA  . SER B 2 261 ? 170.058 140.295 158.155 1.00 40.18  ? 283 SER B CA  1 
ATOM   3420  C C   . SER B 2 261 ? 169.441 139.753 156.874 1.00 40.18  ? 283 SER B C   1 
ATOM   3421  O O   . SER B 2 261 ? 168.217 139.717 156.723 1.00 40.18  ? 283 SER B O   1 
ATOM   3422  C CB  . SER B 2 261 ? 170.229 139.167 159.178 1.00 40.18  ? 283 SER B CB  1 
ATOM   3423  O OG  . SER B 2 261 ? 168.976 138.607 159.531 1.00 40.18  ? 283 SER B OG  1 
ATOM   3424  N N   . PHE B 2 262 ? 170.307 139.330 155.955 1.00 42.67  ? 284 PHE B N   1 
ATOM   3425  C CA  . PHE B 2 262 ? 169.874 138.752 154.692 1.00 42.67  ? 284 PHE B CA  1 
ATOM   3426  C C   . PHE B 2 262 ? 171.027 137.959 154.098 1.00 42.67  ? 284 PHE B C   1 
ATOM   3427  O O   . PHE B 2 262 ? 172.197 138.262 154.344 1.00 42.67  ? 284 PHE B O   1 
ATOM   3428  C CB  . PHE B 2 262 ? 169.400 139.828 153.708 1.00 42.67  ? 284 PHE B CB  1 
ATOM   3429  C CG  . PHE B 2 262 ? 168.766 139.273 152.465 1.00 42.67  ? 284 PHE B CG  1 
ATOM   3430  C CD1 . PHE B 2 262 ? 169.463 139.248 151.268 1.00 42.67  ? 284 PHE B CD1 1 
ATOM   3431  C CD2 . PHE B 2 262 ? 167.476 138.771 152.494 1.00 42.67  ? 284 PHE B CD2 1 
ATOM   3432  C CE1 . PHE B 2 262 ? 168.883 138.736 150.123 1.00 42.67  ? 284 PHE B CE1 1 
ATOM   3433  C CE2 . PHE B 2 262 ? 166.891 138.258 151.352 1.00 42.67  ? 284 PHE B CE2 1 
ATOM   3434  C CZ  . PHE B 2 262 ? 167.596 138.241 150.165 1.00 42.67  ? 284 PHE B CZ  1 
ATOM   3435  N N   . THR B 2 263 ? 170.682 136.941 153.313 1.00 45.31  ? 285 THR B N   1 
ATOM   3436  C CA  . THR B 2 263 ? 171.654 136.035 152.716 1.00 45.31  ? 285 THR B CA  1 
ATOM   3437  C C   . THR B 2 263 ? 171.524 136.071 151.201 1.00 45.31  ? 285 THR B C   1 
ATOM   3438  O O   . THR B 2 263 ? 170.417 135.945 150.666 1.00 45.31  ? 285 THR B O   1 
ATOM   3439  C CB  . THR B 2 263 ? 171.457 134.606 153.229 1.00 45.31  ? 285 THR B CB  1 
ATOM   3440  O OG1 . THR B 2 263 ? 171.626 134.578 154.651 1.00 45.31  ? 285 THR B OG1 1 
ATOM   3441  C CG2 . THR B 2 263 ? 172.462 133.668 152.588 1.00 45.31  ? 285 THR B CG2 1 
ATOM   3442  N N   . VAL B 2 264 ? 172.653 136.242 150.515 1.00 54.86  ? 286 VAL B N   1 
ATOM   3443  C CA  . VAL B 2 264 ? 172.704 136.246 149.056 1.00 54.86  ? 286 VAL B CA  1 
ATOM   3444  C C   . VAL B 2 264 ? 173.135 134.863 148.587 1.00 54.86  ? 286 VAL B C   1 
ATOM   3445  O O   . VAL B 2 264 ? 173.925 134.185 149.258 1.00 54.86  ? 286 VAL B O   1 
ATOM   3446  C CB  . VAL B 2 264 ? 173.655 137.344 148.537 1.00 54.86  ? 286 VAL B CB  1 
ATOM   3447  C CG1 . VAL B 2 264 ? 175.057 137.153 149.097 1.00 54.86  ? 286 VAL B CG1 1 
ATOM   3448  C CG2 . VAL B 2 264 ? 173.669 137.385 147.013 1.00 54.86  ? 286 VAL B CG2 1 
ATOM   3449  N N   . GLN B 2 265 ? 172.609 134.435 147.444 1.00 67.20  ? 287 GLN B N   1 
ATOM   3450  C CA  . GLN B 2 265 ? 172.858 133.105 146.911 1.00 67.20  ? 287 GLN B CA  1 
ATOM   3451  C C   . GLN B 2 265 ? 173.482 133.194 145.523 1.00 67.20  ? 287 GLN B C   1 
ATOM   3452  O O   . GLN B 2 265 ? 173.631 134.274 144.946 1.00 67.20  ? 287 GLN B O   1 
ATOM   3453  C CB  . GLN B 2 265 ? 171.561 132.288 146.852 1.00 67.20  ? 287 GLN B CB  1 
ATOM   3454  C CG  . GLN B 2 265 ? 171.036 131.845 148.207 1.00 67.20  ? 287 GLN B CG  1 
ATOM   3455  C CD  . GLN B 2 265 ? 171.666 130.551 148.683 1.00 67.20  ? 287 GLN B CD  1 
ATOM   3456  O OE1 . GLN B 2 265 ? 172.593 130.033 148.062 1.00 67.20  ? 287 GLN B OE1 1 
ATOM   3457  N NE2 . GLN B 2 265 ? 171.161 130.021 149.791 1.00 67.20  ? 287 GLN B NE2 1 
ATOM   3458  N N   . ASP B 2 266 ? 173.859 132.023 145.004 1.00 73.55  ? 288 ASP B N   1 
ATOM   3459  C CA  . ASP B 2 266 ? 174.315 131.862 143.620 1.00 73.55  ? 288 ASP B CA  1 
ATOM   3460  C C   . ASP B 2 266 ? 175.606 132.633 143.347 1.00 73.55  ? 288 ASP B C   1 
ATOM   3461  O O   . ASP B 2 266 ? 175.761 133.265 142.301 1.00 73.55  ? 288 ASP B O   1 
ATOM   3462  C CB  . ASP B 2 266 ? 173.221 132.270 142.630 1.00 73.55  ? 288 ASP B CB  1 
ATOM   3463  C CG  . ASP B 2 266 ? 171.918 131.531 142.865 1.00 73.55  ? 288 ASP B CG  1 
ATOM   3464  O OD1 . ASP B 2 266 ? 171.963 130.387 143.364 1.00 73.55  ? 288 ASP B OD1 1 
ATOM   3465  O OD2 . ASP B 2 266 ? 170.849 132.095 142.551 1.00 73.55  ? 288 ASP B OD2 1 
ATOM   3466  N N   . LEU B 2 267 ? 176.548 132.578 144.295 1.00 77.25  ? 289 LEU B N   1 
ATOM   3467  C CA  . LEU B 2 267 ? 177.895 133.130 144.113 1.00 77.25  ? 289 LEU B CA  1 
ATOM   3468  C C   . LEU B 2 267 ? 178.888 132.045 144.527 1.00 77.25  ? 289 LEU B C   1 
ATOM   3469  O O   . LEU B 2 267 ? 179.389 132.040 145.653 1.00 77.25  ? 289 LEU B O   1 
ATOM   3470  C CB  . LEU B 2 267 ? 178.077 134.415 144.924 1.00 77.25  ? 289 LEU B CB  1 
ATOM   3471  C CG  . LEU B 2 267 ? 176.951 135.450 144.851 1.00 77.25  ? 289 LEU B CG  1 
ATOM   3472  C CD1 . LEU B 2 267 ? 177.134 136.518 145.918 1.00 77.25  ? 289 LEU B CD1 1 
ATOM   3473  C CD2 . LEU B 2 267 ? 176.882 136.078 143.468 1.00 77.25  ? 289 LEU B CD2 1 
ATOM   3474  N N   . LYS B 2 268 ? 179.172 131.123 143.607 1.00 92.89  ? 290 LYS B N   1 
ATOM   3475  C CA  . LYS B 2 268 ? 180.009 129.972 143.928 1.00 92.89  ? 290 LYS B CA  1 
ATOM   3476  C C   . LYS B 2 268 ? 181.501 130.299 143.994 1.00 92.89  ? 290 LYS B C   1 
ATOM   3477  O O   . LYS B 2 268 ? 182.101 130.192 145.071 1.00 92.89  ? 290 LYS B O   1 
ATOM   3478  C CB  . LYS B 2 268 ? 179.767 128.843 142.918 1.00 92.89  ? 290 LYS B CB  1 
ATOM   3479  C CG  . LYS B 2 268 ? 178.524 128.005 143.180 1.00 92.89  ? 290 LYS B CG  1 
ATOM   3480  C CD  . LYS B 2 268 ? 177.269 128.684 142.653 1.00 92.89  ? 290 LYS B CD  1 
ATOM   3481  C CE  . LYS B 2 268 ? 177.377 128.965 141.163 1.00 92.89  ? 290 LYS B CE  1 
ATOM   3482  N NZ  . LYS B 2 268 ? 176.161 129.647 140.638 1.00 92.89  ? 290 LYS B NZ  1 
ATOM   3483  N N   . PRO B 2 269 ? 182.147 130.701 142.878 1.00 92.44  ? 291 PRO B N   1 
ATOM   3484  C CA  . PRO B 2 269 ? 183.615 130.657 142.847 1.00 92.44  ? 291 PRO B CA  1 
ATOM   3485  C C   . PRO B 2 269 ? 184.312 131.882 143.421 1.00 92.44  ? 291 PRO B C   1 
ATOM   3486  O O   . PRO B 2 269 ? 184.321 132.939 142.783 1.00 92.44  ? 291 PRO B O   1 
ATOM   3487  C CB  . PRO B 2 269 ? 183.915 130.510 141.350 1.00 92.44  ? 291 PRO B CB  1 
ATOM   3488  C CG  . PRO B 2 269 ? 182.699 131.104 140.642 1.00 92.44  ? 291 PRO B CG  1 
ATOM   3489  C CD  . PRO B 2 269 ? 181.622 131.365 141.672 1.00 92.44  ? 291 PRO B CD  1 
ATOM   3490  N N   . PHE B 2 270 ? 184.881 131.741 144.624 1.00 95.62  ? 292 PHE B N   1 
ATOM   3491  C CA  . PHE B 2 270 ? 185.973 132.567 145.143 1.00 95.62  ? 292 PHE B CA  1 
ATOM   3492  C C   . PHE B 2 270 ? 185.936 134.023 144.689 1.00 95.62  ? 292 PHE B C   1 
ATOM   3493  O O   . PHE B 2 270 ? 186.906 134.512 144.101 1.00 95.62  ? 292 PHE B O   1 
ATOM   3494  C CB  . PHE B 2 270 ? 187.317 131.947 144.753 1.00 95.62  ? 292 PHE B CB  1 
ATOM   3495  C CG  . PHE B 2 270 ? 188.444 132.314 145.675 1.00 95.62  ? 292 PHE B CG  1 
ATOM   3496  C CD1 . PHE B 2 270 ? 189.489 133.107 145.233 1.00 95.62  ? 292 PHE B CD1 1 
ATOM   3497  C CD2 . PHE B 2 270 ? 188.457 131.867 146.986 1.00 95.62  ? 292 PHE B CD2 1 
ATOM   3498  C CE1 . PHE B 2 270 ? 190.527 133.446 146.080 1.00 95.62  ? 292 PHE B CE1 1 
ATOM   3499  C CE2 . PHE B 2 270 ? 189.492 132.203 147.838 1.00 95.62  ? 292 PHE B CE2 1 
ATOM   3500  C CZ  . PHE B 2 270 ? 190.528 132.994 147.384 1.00 95.62  ? 292 PHE B CZ  1 
ATOM   3501  N N   . THR B 2 271 ? 184.838 134.725 144.946 1.00 91.68  ? 293 THR B N   1 
ATOM   3502  C CA  . THR B 2 271 ? 184.656 136.084 144.453 1.00 91.68  ? 293 THR B CA  1 
ATOM   3503  C C   . THR B 2 271 ? 184.347 137.021 145.610 1.00 91.68  ? 293 THR B C   1 
ATOM   3504  O O   . THR B 2 271 ? 183.525 136.699 146.474 1.00 91.68  ? 293 THR B O   1 
ATOM   3505  C CB  . THR B 2 271 ? 183.535 136.145 143.411 1.00 91.68  ? 293 THR B CB  1 
ATOM   3506  O OG1 . THR B 2 271 ? 183.767 135.158 142.398 1.00 91.68  ? 293 THR B OG1 1 
ATOM   3507  C CG2 . THR B 2 271 ? 183.484 137.521 142.763 1.00 91.68  ? 293 THR B CG2 1 
ATOM   3508  N N   . GLU B 2 272 ? 185.010 138.173 145.624 1.00 100.22 ? 294 GLU B N   1 
ATOM   3509  C CA  . GLU B 2 272 ? 184.723 139.225 146.587 1.00 100.22 ? 294 GLU B CA  1 
ATOM   3510  C C   . GLU B 2 272 ? 183.643 140.142 146.032 1.00 100.22 ? 294 GLU B C   1 
ATOM   3511  O O   . GLU B 2 272 ? 183.640 140.467 144.841 1.00 100.22 ? 294 GLU B O   1 
ATOM   3512  C CB  . GLU B 2 272 ? 185.987 140.027 146.905 1.00 100.22 ? 294 GLU B CB  1 
ATOM   3513  C CG  . GLU B 2 272 ? 185.839 140.992 148.070 1.00 100.22 ? 294 GLU B CG  1 
ATOM   3514  C CD  . GLU B 2 272 ? 187.085 141.827 148.294 1.00 100.22 ? 294 GLU B CD  1 
ATOM   3515  O OE1 . GLU B 2 272 ? 187.794 142.115 147.308 1.00 100.22 ? 294 GLU B OE1 1 
ATOM   3516  O OE2 . GLU B 2 272 ? 187.355 142.194 149.457 1.00 100.22 ? 294 GLU B OE2 1 
ATOM   3517  N N   . TYR B 2 273 ? 182.721 140.554 146.898 1.00 91.54  ? 295 TYR B N   1 
ATOM   3518  C CA  . TYR B 2 273 ? 181.581 141.357 146.487 1.00 91.54  ? 295 TYR B CA  1 
ATOM   3519  C C   . TYR B 2 273 ? 181.474 142.606 147.350 1.00 91.54  ? 295 TYR B C   1 
ATOM   3520  O O   . TYR B 2 273 ? 181.942 142.638 148.491 1.00 91.54  ? 295 TYR B O   1 
ATOM   3521  C CB  . TYR B 2 273 ? 180.276 140.555 146.566 1.00 91.54  ? 295 TYR B CB  1 
ATOM   3522  C CG  . TYR B 2 273 ? 180.248 139.357 145.646 1.00 91.54  ? 295 TYR B CG  1 
ATOM   3523  C CD1 . TYR B 2 273 ? 179.838 139.482 144.326 1.00 91.54  ? 295 TYR B CD1 1 
ATOM   3524  C CD2 . TYR B 2 273 ? 180.635 138.102 146.096 1.00 91.54  ? 295 TYR B CD2 1 
ATOM   3525  C CE1 . TYR B 2 273 ? 179.812 138.390 143.480 1.00 91.54  ? 295 TYR B CE1 1 
ATOM   3526  C CE2 . TYR B 2 273 ? 180.612 137.005 145.257 1.00 91.54  ? 295 TYR B CE2 1 
ATOM   3527  C CZ  . TYR B 2 273 ? 180.200 137.155 143.950 1.00 91.54  ? 295 TYR B CZ  1 
ATOM   3528  O OH  . TYR B 2 273 ? 180.176 136.066 143.109 1.00 91.54  ? 295 TYR B OH  1 
ATOM   3529  N N   . VAL B 2 274 ? 180.848 143.635 146.785 1.00 77.22  ? 296 VAL B N   1 
ATOM   3530  C CA  . VAL B 2 274 ? 180.604 144.899 147.468 1.00 77.22  ? 296 VAL B CA  1 
ATOM   3531  C C   . VAL B 2 274 ? 179.101 145.059 147.646 1.00 77.22  ? 296 VAL B C   1 
ATOM   3532  O O   . VAL B 2 274 ? 178.323 144.756 146.733 1.00 77.22  ? 296 VAL B O   1 
ATOM   3533  C CB  . VAL B 2 274 ? 181.198 146.087 146.686 1.00 77.22  ? 296 VAL B CB  1 
ATOM   3534  C CG1 . VAL B 2 274 ? 181.093 147.367 147.499 1.00 77.22  ? 296 VAL B CG1 1 
ATOM   3535  C CG2 . VAL B 2 274 ? 182.644 145.803 146.309 1.00 77.22  ? 296 VAL B CG2 1 
ATOM   3536  N N   . PHE B 2 275 ? 178.693 145.536 148.819 1.00 64.52  ? 297 PHE B N   1 
ATOM   3537  C CA  . PHE B 2 275 ? 177.285 145.655 149.161 1.00 64.52  ? 297 PHE B CA  1 
ATOM   3538  C C   . PHE B 2 275 ? 176.965 147.077 149.598 1.00 64.52  ? 297 PHE B C   1 
ATOM   3539  O O   . PHE B 2 275 ? 177.794 147.763 150.202 1.00 64.52  ? 297 PHE B O   1 
ATOM   3540  C CB  . PHE B 2 275 ? 176.895 144.673 150.276 1.00 64.52  ? 297 PHE B CB  1 
ATOM   3541  C CG  . PHE B 2 275 ? 176.954 143.229 149.863 1.00 64.52  ? 297 PHE B CG  1 
ATOM   3542  C CD1 . PHE B 2 275 ? 175.813 142.569 149.438 1.00 64.52  ? 297 PHE B CD1 1 
ATOM   3543  C CD2 . PHE B 2 275 ? 178.149 142.531 149.903 1.00 64.52  ? 297 PHE B CD2 1 
ATOM   3544  C CE1 . PHE B 2 275 ? 175.863 141.241 149.059 1.00 64.52  ? 297 PHE B CE1 1 
ATOM   3545  C CE2 . PHE B 2 275 ? 178.205 141.203 149.525 1.00 64.52  ? 297 PHE B CE2 1 
ATOM   3546  C CZ  . PHE B 2 275 ? 177.061 140.557 149.103 1.00 64.52  ? 297 PHE B CZ  1 
ATOM   3547  N N   . ARG B 2 276 ? 175.747 147.510 149.282 1.00 62.00  ? 298 ARG B N   1 
ATOM   3548  C CA  . ARG B 2 276 ? 175.235 148.798 149.722 1.00 62.00  ? 298 ARG B CA  1 
ATOM   3549  C C   . ARG B 2 276 ? 173.729 148.680 149.894 1.00 62.00  ? 298 ARG B C   1 
ATOM   3550  O O   . ARG B 2 276 ? 173.073 147.895 149.203 1.00 62.00  ? 298 ARG B O   1 
ATOM   3551  C CB  . ARG B 2 276 ? 175.583 149.921 148.737 1.00 62.00  ? 298 ARG B CB  1 
ATOM   3552  C CG  . ARG B 2 276 ? 175.032 149.724 147.336 1.00 62.00  ? 298 ARG B CG  1 
ATOM   3553  C CD  . ARG B 2 276 ? 175.403 150.894 146.440 1.00 62.00  ? 298 ARG B CD  1 
ATOM   3554  N NE  . ARG B 2 276 ? 174.895 150.731 145.081 1.00 62.00  ? 298 ARG B NE  1 
ATOM   3555  C CZ  . ARG B 2 276 ? 175.136 151.582 144.089 1.00 62.00  ? 298 ARG B CZ  1 
ATOM   3556  N NH1 . ARG B 2 276 ? 175.880 152.659 144.302 1.00 62.00  ? 298 ARG B NH1 1 
ATOM   3557  N NH2 . ARG B 2 276 ? 174.634 151.355 142.883 1.00 62.00  ? 298 ARG B NH2 1 
ATOM   3558  N N   . ILE B 2 277 ? 173.185 149.462 150.823 1.00 45.56  ? 299 ILE B N   1 
ATOM   3559  C CA  . ILE B 2 277 ? 171.784 149.328 151.206 1.00 45.56  ? 299 ILE B CA  1 
ATOM   3560  C C   . ILE B 2 277 ? 171.221 150.706 151.523 1.00 45.56  ? 299 ILE B C   1 
ATOM   3561  O O   . ILE B 2 277 ? 171.930 151.584 152.025 1.00 45.56  ? 299 ILE B O   1 
ATOM   3562  C CB  . ILE B 2 277 ? 171.629 148.359 152.401 1.00 45.56  ? 299 ILE B CB  1 
ATOM   3563  C CG1 . ILE B 2 277 ? 170.157 148.028 152.651 1.00 45.56  ? 299 ILE B CG1 1 
ATOM   3564  C CG2 . ILE B 2 277 ? 172.280 148.931 153.654 1.00 45.56  ? 299 ILE B CG2 1 
ATOM   3565  C CD1 . ILE B 2 277 ? 169.956 146.864 153.595 1.00 45.56  ? 299 ILE B CD1 1 
ATOM   3566  N N   . ARG B 2 278 ? 169.943 150.896 151.203 1.00 41.57  ? 300 ARG B N   1 
ATOM   3567  C CA  . ARG B 2 278 ? 169.189 152.083 151.574 1.00 41.57  ? 300 ARG B CA  1 
ATOM   3568  C C   . ARG B 2 278 ? 167.871 151.647 152.200 1.00 41.57  ? 300 ARG B C   1 
ATOM   3569  O O   . ARG B 2 278 ? 167.561 150.455 152.275 1.00 41.57  ? 300 ARG B O   1 
ATOM   3570  C CB  . ARG B 2 278 ? 168.943 152.996 150.364 1.00 41.57  ? 300 ARG B CB  1 
ATOM   3571  C CG  . ARG B 2 278 ? 168.169 152.339 149.235 1.00 41.57  ? 300 ARG B CG  1 
ATOM   3572  C CD  . ARG B 2 278 ? 167.803 153.350 148.161 1.00 41.57  ? 300 ARG B CD  1 
ATOM   3573  N NE  . ARG B 2 278 ? 166.994 152.753 147.103 1.00 41.57  ? 300 ARG B NE  1 
ATOM   3574  C CZ  . ARG B 2 278 ? 166.473 153.433 146.087 1.00 41.57  ? 300 ARG B CZ  1 
ATOM   3575  N NH1 . ARG B 2 278 ? 166.675 154.739 145.988 1.00 41.57  ? 300 ARG B NH1 1 
ATOM   3576  N NH2 . ARG B 2 278 ? 165.749 152.807 145.170 1.00 41.57  ? 300 ARG B NH2 1 
ATOM   3577  N N   . CYS B 2 279 ? 167.086 152.622 152.655 1.00 40.51  ? 301 CYS B N   1 
ATOM   3578  C CA  . CYS B 2 279 ? 165.834 152.311 153.328 1.00 40.51  ? 301 CYS B CA  1 
ATOM   3579  C C   . CYS B 2 279 ? 164.889 153.502 153.254 1.00 40.51  ? 301 CYS B C   1 
ATOM   3580  O O   . CYS B 2 279 ? 165.320 154.656 153.193 1.00 40.51  ? 301 CYS B O   1 
ATOM   3581  C CB  . CYS B 2 279 ? 166.070 151.918 154.791 1.00 40.51  ? 301 CYS B CB  1 
ATOM   3582  S SG  . CYS B 2 279 ? 167.215 152.998 155.678 1.00 40.51  ? 301 CYS B SG  1 
ATOM   3583  N N   . MET B 2 280 ? 163.595 153.202 153.263 1.00 33.47  ? 302 MET B N   1 
ATOM   3584  C CA  . MET B 2 280 ? 162.541 154.210 153.299 1.00 33.47  ? 302 MET B CA  1 
ATOM   3585  C C   . MET B 2 280 ? 161.300 153.560 153.902 1.00 33.47  ? 302 MET B C   1 
ATOM   3586  O O   . MET B 2 280 ? 161.342 152.409 154.349 1.00 33.47  ? 302 MET B O   1 
ATOM   3587  C CB  . MET B 2 280 ? 162.279 154.785 151.902 1.00 33.47  ? 302 MET B CB  1 
ATOM   3588  C CG  . MET B 2 280 ? 161.437 153.893 151.001 1.00 33.47  ? 302 MET B CG  1 
ATOM   3589  S SD  . MET B 2 280 ? 160.682 154.802 149.639 1.00 33.47  ? 302 MET B SD  1 
ATOM   3590  C CE  . MET B 2 280 ? 159.764 156.051 150.534 1.00 33.47  ? 302 MET B CE  1 
ATOM   3591  N N   . LYS B 2 281 ? 160.192 154.297 153.920 1.00 36.16  ? 303 LYS B N   1 
ATOM   3592  C CA  . LYS B 2 281 ? 158.949 153.754 154.447 1.00 36.16  ? 303 LYS B CA  1 
ATOM   3593  C C   . LYS B 2 281 ? 158.482 152.569 153.603 1.00 36.16  ? 303 LYS B C   1 
ATOM   3594  O O   . LYS B 2 281 ? 158.840 152.422 152.431 1.00 36.16  ? 303 LYS B O   1 
ATOM   3595  C CB  . LYS B 2 281 ? 157.869 154.834 154.492 1.00 36.16  ? 303 LYS B CB  1 
ATOM   3596  C CG  . LYS B 2 281 ? 156.841 154.631 155.593 1.00 36.16  ? 303 LYS B CG  1 
ATOM   3597  C CD  . LYS B 2 281 ? 155.875 155.800 155.676 1.00 36.16  ? 303 LYS B CD  1 
ATOM   3598  C CE  . LYS B 2 281 ? 154.918 155.639 156.845 1.00 36.16  ? 303 LYS B CE  1 
ATOM   3599  N NZ  . LYS B 2 281 ? 154.139 154.373 156.755 1.00 36.16  ? 303 LYS B NZ  1 
ATOM   3600  N N   . GLU B 2 282 ? 157.664 151.714 154.222 1.00 38.33  ? 304 GLU B N   1 
ATOM   3601  C CA  . GLU B 2 282 ? 157.241 150.480 153.566 1.00 38.33  ? 304 GLU B CA  1 
ATOM   3602  C C   . GLU B 2 282 ? 156.316 150.763 152.388 1.00 38.33  ? 304 GLU B C   1 
ATOM   3603  O O   . GLU B 2 282 ? 156.519 150.238 151.287 1.00 38.33  ? 304 GLU B O   1 
ATOM   3604  C CB  . GLU B 2 282 ? 156.558 149.558 154.576 1.00 38.33  ? 304 GLU B CB  1 
ATOM   3605  C CG  . GLU B 2 282 ? 155.634 148.528 153.945 1.00 38.33  ? 304 GLU B CG  1 
ATOM   3606  C CD  . GLU B 2 282 ? 155.056 147.563 154.960 1.00 38.33  ? 304 GLU B CD  1 
ATOM   3607  O OE1 . GLU B 2 282 ? 155.842 146.920 155.687 1.00 38.33  ? 304 GLU B OE1 1 
ATOM   3608  O OE2 . GLU B 2 282 ? 153.815 147.447 155.032 1.00 38.33  ? 304 GLU B OE2 1 
ATOM   3609  N N   . ASP B 2 283 ? 155.293 151.593 152.598 1.00 52.50  ? 305 ASP B N   1 
ATOM   3610  C CA  . ASP B 2 283 ? 154.315 151.870 151.551 1.00 52.50  ? 305 ASP B CA  1 
ATOM   3611  C C   . ASP B 2 283 ? 154.867 152.733 150.422 1.00 52.50  ? 305 ASP B C   1 
ATOM   3612  O O   . ASP B 2 283 ? 154.106 153.082 149.513 1.00 52.50  ? 305 ASP B O   1 
ATOM   3613  C CB  . ASP B 2 283 ? 153.077 152.535 152.156 1.00 52.50  ? 305 ASP B CB  1 
ATOM   3614  C CG  . ASP B 2 283 ? 153.424 153.697 153.064 1.00 52.50  ? 305 ASP B CG  1 
ATOM   3615  O OD1 . ASP B 2 283 ? 154.626 153.997 153.217 1.00 52.50  ? 305 ASP B OD1 1 
ATOM   3616  O OD2 . ASP B 2 283 ? 152.493 154.310 153.628 1.00 52.50  ? 305 ASP B OD2 1 
ATOM   3617  N N   . GLY B 2 284 ? 156.150 153.085 150.452 1.00 47.79  ? 306 GLY B N   1 
ATOM   3618  C CA  . GLY B 2 284 ? 156.745 153.867 149.388 1.00 47.79  ? 306 GLY B CA  1 
ATOM   3619  C C   . GLY B 2 284 ? 156.501 155.356 149.465 1.00 47.79  ? 306 GLY B C   1 
ATOM   3620  O O   . GLY B 2 284 ? 156.797 156.065 148.497 1.00 47.79  ? 306 GLY B O   1 
ATOM   3621  N N   . LYS B 2 285 ? 155.974 155.855 150.579 1.00 33.01  ? 307 LYS B N   1 
ATOM   3622  C CA  . LYS B 2 285 ? 155.711 157.276 150.758 1.00 33.01  ? 307 LYS B CA  1 
ATOM   3623  C C   . LYS B 2 285 ? 156.878 157.902 151.512 1.00 33.01  ? 307 LYS B C   1 
ATOM   3624  O O   . LYS B 2 285 ? 157.201 157.478 152.627 1.00 33.01  ? 307 LYS B O   1 
ATOM   3625  C CB  . LYS B 2 285 ? 154.400 157.497 151.510 1.00 33.01  ? 307 LYS B CB  1 
ATOM   3626  C CG  . LYS B 2 285 ? 153.238 156.673 150.980 1.00 33.01  ? 307 LYS B CG  1 
ATOM   3627  C CD  . LYS B 2 285 ? 152.899 157.054 149.549 1.00 33.01  ? 307 LYS B CD  1 
ATOM   3628  C CE  . LYS B 2 285 ? 152.311 158.453 149.476 1.00 33.01  ? 307 LYS B CE  1 
ATOM   3629  N NZ  . LYS B 2 285 ? 151.033 158.556 150.232 1.00 33.01  ? 307 LYS B NZ  1 
ATOM   3630  N N   . GLY B 2 286 ? 157.504 158.911 150.905 1.00 27.16  ? 308 GLY B N   1 
ATOM   3631  C CA  . GLY B 2 286 ? 158.655 159.570 151.483 1.00 27.16  ? 308 GLY B CA  1 
ATOM   3632  C C   . GLY B 2 286 ? 159.817 159.620 150.505 1.00 27.16  ? 308 GLY B C   1 
ATOM   3633  O O   . GLY B 2 286 ? 159.622 159.705 149.287 1.00 27.16  ? 308 GLY B O   1 
ATOM   3634  N N   . TYR B 2 287 ? 161.027 159.565 151.055 1.00 37.17  ? 309 TYR B N   1 
ATOM   3635  C CA  . TYR B 2 287 ? 162.246 159.605 150.262 1.00 37.17  ? 309 TYR B CA  1 
ATOM   3636  C C   . TYR B 2 287 ? 163.179 158.484 150.695 1.00 37.17  ? 309 TYR B C   1 
ATOM   3637  O O   . TYR B 2 287 ? 163.246 158.132 151.876 1.00 37.17  ? 309 TYR B O   1 
ATOM   3638  C CB  . TYR B 2 287 ? 162.961 160.957 150.394 1.00 37.17  ? 309 TYR B CB  1 
ATOM   3639  C CG  . TYR B 2 287 ? 162.072 162.150 150.127 1.00 37.17  ? 309 TYR B CG  1 
ATOM   3640  C CD1 . TYR B 2 287 ? 161.808 162.567 148.829 1.00 37.17  ? 309 TYR B CD1 1 
ATOM   3641  C CD2 . TYR B 2 287 ? 161.498 162.862 151.172 1.00 37.17  ? 309 TYR B CD2 1 
ATOM   3642  C CE1 . TYR B 2 287 ? 160.997 163.657 148.579 1.00 37.17  ? 309 TYR B CE1 1 
ATOM   3643  C CE2 . TYR B 2 287 ? 160.685 163.954 150.932 1.00 37.17  ? 309 TYR B CE2 1 
ATOM   3644  C CZ  . TYR B 2 287 ? 160.438 164.346 149.634 1.00 37.17  ? 309 TYR B CZ  1 
ATOM   3645  O OH  . TYR B 2 287 ? 159.629 165.432 149.389 1.00 37.17  ? 309 TYR B OH  1 
ATOM   3646  N N   . TRP B 2 288 ? 163.899 157.927 149.725 1.00 38.29  ? 310 TRP B N   1 
ATOM   3647  C CA  . TRP B 2 288 ? 164.871 156.882 150.008 1.00 38.29  ? 310 TRP B CA  1 
ATOM   3648  C C   . TRP B 2 288 ? 166.087 157.470 150.709 1.00 38.29  ? 310 TRP B C   1 
ATOM   3649  O O   . TRP B 2 288 ? 166.540 158.571 150.382 1.00 38.29  ? 310 TRP B O   1 
ATOM   3650  C CB  . TRP B 2 288 ? 165.303 156.184 148.718 1.00 38.29  ? 310 TRP B CB  1 
ATOM   3651  C CG  . TRP B 2 288 ? 164.341 155.141 148.235 1.00 38.29  ? 310 TRP B CG  1 
ATOM   3652  C CD1 . TRP B 2 288 ? 163.482 155.244 147.181 1.00 38.29  ? 310 TRP B CD1 1 
ATOM   3653  C CD2 . TRP B 2 288 ? 164.145 153.831 148.784 1.00 38.29  ? 310 TRP B CD2 1 
ATOM   3654  N NE1 . TRP B 2 288 ? 162.761 154.084 147.041 1.00 38.29  ? 310 TRP B NE1 1 
ATOM   3655  C CE2 . TRP B 2 288 ? 163.150 153.200 148.012 1.00 38.29  ? 310 TRP B CE2 1 
ATOM   3656  C CE3 . TRP B 2 288 ? 164.713 153.133 149.854 1.00 38.29  ? 310 TRP B CE3 1 
ATOM   3657  C CZ2 . TRP B 2 288 ? 162.710 151.905 148.277 1.00 38.29  ? 310 TRP B CZ2 1 
ATOM   3658  C CZ3 . TRP B 2 288 ? 164.275 151.847 150.114 1.00 38.29  ? 310 TRP B CZ3 1 
ATOM   3659  C CH2 . TRP B 2 288 ? 163.283 151.247 149.330 1.00 38.29  ? 310 TRP B CH2 1 
ATOM   3660  N N   . SER B 2 289 ? 166.616 156.730 151.680 1.00 46.79  ? 311 SER B N   1 
ATOM   3661  C CA  . SER B 2 289 ? 167.793 157.180 152.402 1.00 46.79  ? 311 SER B CA  1 
ATOM   3662  C C   . SER B 2 289 ? 169.032 157.079 151.516 1.00 46.79  ? 311 SER B C   1 
ATOM   3663  O O   . SER B 2 289 ? 169.003 156.530 150.411 1.00 46.79  ? 311 SER B O   1 
ATOM   3664  C CB  . SER B 2 289 ? 167.987 156.362 153.678 1.00 46.79  ? 311 SER B CB  1 
ATOM   3665  O OG  . SER B 2 289 ? 168.202 154.994 153.377 1.00 46.79  ? 311 SER B OG  1 
ATOM   3666  N N   . ASP B 2 290 ? 170.136 157.622 152.019 1.00 55.30  ? 312 ASP B N   1 
ATOM   3667  C CA  . ASP B 2 290 ? 171.394 157.553 151.295 1.00 55.30  ? 312 ASP B CA  1 
ATOM   3668  C C   . ASP B 2 290 ? 171.917 156.118 151.272 1.00 55.30  ? 312 ASP B C   1 
ATOM   3669  O O   . ASP B 2 290 ? 171.478 155.253 152.035 1.00 55.30  ? 312 ASP B O   1 
ATOM   3670  C CB  . ASP B 2 290 ? 172.429 158.483 151.928 1.00 55.30  ? 312 ASP B CB  1 
ATOM   3671  C CG  . ASP B 2 290 ? 173.464 158.967 150.931 1.00 55.30  ? 312 ASP B CG  1 
ATOM   3672  O OD1 . ASP B 2 290 ? 173.693 158.269 149.921 1.00 55.30  ? 312 ASP B OD1 1 
ATOM   3673  O OD2 . ASP B 2 290 ? 174.048 160.048 151.158 1.00 55.30  ? 312 ASP B OD2 1 
ATOM   3674  N N   . TRP B 2 291 ? 172.867 155.872 150.376 1.00 50.18  ? 313 TRP B N   1 
ATOM   3675  C CA  . TRP B 2 291 ? 173.463 154.550 150.255 1.00 50.18  ? 313 TRP B CA  1 
ATOM   3676  C C   . TRP B 2 291 ? 174.495 154.332 151.353 1.00 50.18  ? 313 TRP B C   1 
ATOM   3677  O O   . TRP B 2 291 ? 175.274 155.231 151.681 1.00 50.18  ? 313 TRP B O   1 
ATOM   3678  C CB  . TRP B 2 291 ? 174.108 154.377 148.880 1.00 50.18  ? 313 TRP B CB  1 
ATOM   3679  C CG  . TRP B 2 291 ? 173.113 154.296 147.763 1.00 50.18  ? 313 TRP B CG  1 
ATOM   3680  C CD1 . TRP B 2 291 ? 172.819 155.270 146.855 1.00 50.18  ? 313 TRP B CD1 1 
ATOM   3681  C CD2 . TRP B 2 291 ? 172.275 153.179 147.440 1.00 50.18  ? 313 TRP B CD2 1 
ATOM   3682  N NE1 . TRP B 2 291 ? 171.852 154.829 145.984 1.00 50.18  ? 313 TRP B NE1 1 
ATOM   3683  C CE2 . TRP B 2 291 ? 171.501 153.548 146.322 1.00 50.18  ? 313 TRP B CE2 1 
ATOM   3684  C CE3 . TRP B 2 291 ? 172.106 151.903 147.986 1.00 50.18  ? 313 TRP B CE3 1 
ATOM   3685  C CZ2 . TRP B 2 291 ? 170.573 152.688 145.741 1.00 50.18  ? 313 TRP B CZ2 1 
ATOM   3686  C CZ3 . TRP B 2 291 ? 171.183 151.051 147.407 1.00 50.18  ? 313 TRP B CZ3 1 
ATOM   3687  C CH2 . TRP B 2 291 ? 170.428 151.447 146.296 1.00 50.18  ? 313 TRP B CH2 1 
ATOM   3688  N N   . SER B 2 292 ? 174.493 153.129 151.921 1.00 61.87  ? 314 SER B N   1 
ATOM   3689  C CA  . SER B 2 292 ? 175.414 152.803 152.996 1.00 61.87  ? 314 SER B CA  1 
ATOM   3690  C C   . SER B 2 292 ? 176.848 152.739 152.472 1.00 61.87  ? 314 SER B C   1 
ATOM   3691  O O   . SER B 2 292 ? 177.105 152.757 151.264 1.00 61.87  ? 314 SER B O   1 
ATOM   3692  C CB  . SER B 2 292 ? 175.028 151.475 153.647 1.00 61.87  ? 314 SER B CB  1 
ATOM   3693  O OG  . SER B 2 292 ? 175.120 150.407 152.721 1.00 61.87  ? 314 SER B OG  1 
ATOM   3694  N N   . GLU B 2 293 ? 177.792 152.664 153.406 1.00 69.93  ? 315 GLU B N   1 
ATOM   3695  C CA  . GLU B 2 293 ? 179.199 152.587 153.041 1.00 69.93  ? 315 GLU B CA  1 
ATOM   3696  C C   . GLU B 2 293 ? 179.495 151.269 152.337 1.00 69.93  ? 315 GLU B C   1 
ATOM   3697  O O   . GLU B 2 293 ? 178.934 150.223 152.677 1.00 69.93  ? 315 GLU B O   1 
ATOM   3698  C CB  . GLU B 2 293 ? 180.080 152.732 154.281 1.00 69.93  ? 315 GLU B CB  1 
ATOM   3699  C CG  . GLU B 2 293 ? 179.791 153.975 155.105 1.00 69.93  ? 315 GLU B CG  1 
ATOM   3700  C CD  . GLU B 2 293 ? 180.780 154.166 156.237 1.00 69.93  ? 315 GLU B CD  1 
ATOM   3701  O OE1 . GLU B 2 293 ? 181.939 153.721 156.097 1.00 69.93  ? 315 GLU B OE1 1 
ATOM   3702  O OE2 . GLU B 2 293 ? 180.400 154.762 157.267 1.00 69.93  ? 315 GLU B OE2 1 
ATOM   3703  N N   . GLU B 2 294 ? 180.381 151.326 151.346 1.00 84.77  ? 316 GLU B N   1 
ATOM   3704  C CA  . GLU B 2 294 ? 180.731 150.139 150.577 1.00 84.77  ? 316 GLU B CA  1 
ATOM   3705  C C   . GLU B 2 294 ? 181.550 149.184 151.437 1.00 84.77  ? 316 GLU B C   1 
ATOM   3706  O O   . GLU B 2 294 ? 182.675 149.504 151.835 1.00 84.77  ? 316 GLU B O   1 
ATOM   3707  C CB  . GLU B 2 294 ? 181.505 150.534 149.322 1.00 84.77  ? 316 GLU B CB  1 
ATOM   3708  C CG  . GLU B 2 294 ? 180.638 151.121 148.221 1.00 84.77  ? 316 GLU B CG  1 
ATOM   3709  C CD  . GLU B 2 294 ? 181.439 151.509 146.994 1.00 84.77  ? 316 GLU B CD  1 
ATOM   3710  O OE1 . GLU B 2 294 ? 182.509 152.132 147.154 1.00 84.77  ? 316 GLU B OE1 1 
ATOM   3711  O OE2 . GLU B 2 294 ? 180.997 151.191 145.870 1.00 84.77  ? 316 GLU B OE2 1 
ATOM   3712  N N   . ALA B 2 295 ? 180.986 148.015 151.722 1.00 83.12  ? 317 ALA B N   1 
ATOM   3713  C CA  . ALA B 2 295 ? 181.642 146.994 152.524 1.00 83.12  ? 317 ALA B CA  1 
ATOM   3714  C C   . ALA B 2 295 ? 182.018 145.810 151.644 1.00 83.12  ? 317 ALA B C   1 
ATOM   3715  O O   . ALA B 2 295 ? 181.251 145.411 150.762 1.00 83.12  ? 317 ALA B O   1 
ATOM   3716  C CB  . ALA B 2 295 ? 180.740 146.529 153.670 1.00 83.12  ? 317 ALA B CB  1 
ATOM   3717  N N   . SER B 2 296 ? 183.198 145.253 151.889 1.00 91.16  ? 318 SER B N   1 
ATOM   3718  C CA  . SER B 2 296 ? 183.715 144.136 151.115 1.00 91.16  ? 318 SER B CA  1 
ATOM   3719  C C   . SER B 2 296 ? 183.525 142.825 151.869 1.00 91.16  ? 318 SER B C   1 
ATOM   3720  O O   . SER B 2 296 ? 183.382 142.796 153.094 1.00 91.16  ? 318 SER B O   1 
ATOM   3721  C CB  . SER B 2 296 ? 185.196 144.344 150.787 1.00 91.16  ? 318 SER B CB  1 
ATOM   3722  O OG  . SER B 2 296 ? 185.438 145.666 150.340 1.00 91.16  ? 318 SER B OG  1 
ATOM   3723  N N   . GLY B 2 297 ? 183.525 141.731 151.113 1.00 92.60  ? 319 GLY B N   1 
ATOM   3724  C CA  . GLY B 2 297 ? 183.373 140.410 151.689 1.00 92.60  ? 319 GLY B CA  1 
ATOM   3725  C C   . GLY B 2 297 ? 183.711 139.301 150.715 1.00 92.60  ? 319 GLY B C   1 
ATOM   3726  O O   . GLY B 2 297 ? 183.250 139.309 149.570 1.00 92.60  ? 319 GLY B O   1 
ATOM   3727  N N   . ILE B 2 298 ? 184.516 138.338 151.159 1.00 92.85  ? 320 ILE B N   1 
ATOM   3728  C CA  . ILE B 2 298 ? 184.939 137.216 150.330 1.00 92.85  ? 320 ILE B CA  1 
ATOM   3729  C C   . ILE B 2 298 ? 184.126 135.991 150.720 1.00 92.85  ? 320 ILE B C   1 
ATOM   3730  O O   . ILE B 2 298 ? 184.022 135.657 151.907 1.00 92.85  ? 320 ILE B O   1 
ATOM   3731  C CB  . ILE B 2 298 ? 186.446 136.947 150.482 1.00 92.85  ? 320 ILE B CB  1 
ATOM   3732  C CG1 . ILE B 2 298 ? 187.247 138.220 150.199 1.00 92.85  ? 320 ILE B CG1 1 
ATOM   3733  C CG2 . ILE B 2 298 ? 186.883 135.823 149.555 1.00 92.85  ? 320 ILE B CG2 1 
ATOM   3734  C CD1 . ILE B 2 298 ? 188.741 138.050 150.365 1.00 92.85  ? 320 ILE B CD1 1 
ATOM   3735  N N   . THR B 2 299 ? 183.551 135.321 149.725 1.00 84.37  ? 321 THR B N   1 
ATOM   3736  C CA  . THR B 2 299 ? 182.758 134.129 149.971 1.00 84.37  ? 321 THR B CA  1 
ATOM   3737  C C   . THR B 2 299 ? 183.669 132.916 150.147 1.00 84.37  ? 321 THR B C   1 
ATOM   3738  O O   . THR B 2 299 ? 184.894 132.996 150.012 1.00 84.37  ? 321 THR B O   1 
ATOM   3739  C CB  . THR B 2 299 ? 181.771 133.897 148.829 1.00 84.37  ? 321 THR B CB  1 
ATOM   3740  O OG1 . THR B 2 299 ? 182.442 133.253 147.738 1.00 84.37  ? 321 THR B OG1 1 
ATOM   3741  C CG2 . THR B 2 299 ? 181.196 135.217 148.347 1.00 84.37  ? 321 THR B CG2 1 
ATOM   3742  N N   . TYR B 2 300 ? 183.062 131.775 150.452 1.00 93.78  ? 322 TYR B N   1 
ATOM   3743  C CA  . TYR B 2 300 ? 183.803 130.530 150.548 1.00 93.78  ? 322 TYR B CA  1 
ATOM   3744  C C   . TYR B 2 300 ? 184.045 129.959 149.156 1.00 93.78  ? 322 TYR B C   1 
ATOM   3745  O O   . TYR B 2 300 ? 183.291 130.220 148.214 1.00 93.78  ? 322 TYR B O   1 
ATOM   3746  C CB  . TYR B 2 300 ? 183.049 129.522 151.415 1.00 93.78  ? 322 TYR B CB  1 
ATOM   3747  C CG  . TYR B 2 300 ? 183.862 128.309 151.803 1.00 93.78  ? 322 TYR B CG  1 
ATOM   3748  C CD1 . TYR B 2 300 ? 183.486 127.037 151.392 1.00 93.78  ? 322 TYR B CD1 1 
ATOM   3749  C CD2 . TYR B 2 300 ? 185.007 128.435 152.578 1.00 93.78  ? 322 TYR B CD2 1 
ATOM   3750  C CE1 . TYR B 2 300 ? 184.225 125.925 151.744 1.00 93.78  ? 322 TYR B CE1 1 
ATOM   3751  C CE2 . TYR B 2 300 ? 185.753 127.329 152.935 1.00 93.78  ? 322 TYR B CE2 1 
ATOM   3752  C CZ  . TYR B 2 300 ? 185.358 126.076 152.515 1.00 93.78  ? 322 TYR B CZ  1 
ATOM   3753  O OH  . TYR B 2 300 ? 186.097 124.971 152.867 1.00 93.78  ? 322 TYR B OH  1 
ATOM   3754  N N   . GLU B 2 301 ? 185.110 129.175 149.033 1.00 104.22 ? 323 GLU B N   1 
ATOM   3755  C CA  . GLU B 2 301 ? 185.554 128.662 147.745 1.00 104.22 ? 323 GLU B CA  1 
ATOM   3756  C C   . GLU B 2 301 ? 184.989 127.270 147.495 1.00 104.22 ? 323 GLU B C   1 
ATOM   3757  O O   . GLU B 2 301 ? 184.881 126.453 148.415 1.00 104.22 ? 323 GLU B O   1 
ATOM   3758  C CB  . GLU B 2 301 ? 187.083 128.627 147.669 1.00 104.22 ? 323 GLU B CB  1 
ATOM   3759  C CG  . GLU B 2 301 ? 187.752 127.713 148.687 1.00 104.22 ? 323 GLU B CG  1 
ATOM   3760  C CD  . GLU B 2 301 ? 187.918 128.367 150.045 1.00 104.22 ? 323 GLU B CD  1 
ATOM   3761  O OE1 . GLU B 2 301 ? 187.646 129.581 150.159 1.00 104.22 ? 323 GLU B OE1 1 
ATOM   3762  O OE2 . GLU B 2 301 ? 188.320 127.668 150.998 1.00 104.22 ? 323 GLU B OE2 1 
ATOM   3763  N N   . ASP B 2 302 ? 184.618 127.013 146.245 1.00 121.20 ? 324 ASP B N   1 
ATOM   3764  C CA  . ASP B 2 302 ? 184.214 125.691 145.794 1.00 121.20 ? 324 ASP B CA  1 
ATOM   3765  C C   . ASP B 2 302 ? 185.365 125.046 145.032 1.00 121.20 ? 324 ASP B C   1 
ATOM   3766  O O   . ASP B 2 302 ? 186.187 125.731 144.419 1.00 121.20 ? 324 ASP B O   1 
ATOM   3767  C CB  . ASP B 2 302 ? 182.970 125.768 144.907 1.00 121.20 ? 324 ASP B CB  1 
ATOM   3768  C CG  . ASP B 2 302 ? 182.291 124.423 144.738 1.00 121.20 ? 324 ASP B CG  1 
ATOM   3769  O OD1 . ASP B 2 302 ? 182.700 123.458 145.417 1.00 121.20 ? 324 ASP B OD1 1 
ATOM   3770  O OD2 . ASP B 2 302 ? 181.347 124.330 143.925 1.00 121.20 ? 324 ASP B OD2 1 
ATOM   3771  N N   . ARG B 2 303 ? 185.419 123.716 145.076 1.00 110.66 ? 325 ARG B N   1 
ATOM   3772  C CA  . ARG B 2 303 ? 186.533 122.954 144.511 1.00 110.66 ? 325 ARG B CA  1 
ATOM   3773  C C   . ARG B 2 303 ? 186.021 121.914 143.522 1.00 110.66 ? 325 ARG B C   1 
ATOM   3774  O O   . ARG B 2 303 ? 185.969 120.716 143.834 1.00 110.66 ? 325 ARG B O   1 
ATOM   3775  C CB  . ARG B 2 303 ? 187.352 122.292 145.619 1.00 110.66 ? 325 ARG B CB  1 
ATOM   3776  C CG  . ARG B 2 303 ? 187.709 123.225 146.766 1.00 110.66 ? 325 ARG B CG  1 
ATOM   3777  C CD  . ARG B 2 303 ? 188.106 122.448 148.009 1.00 110.66 ? 325 ARG B CD  1 
ATOM   3778  N NE  . ARG B 2 303 ? 188.377 123.328 149.141 1.00 110.66 ? 325 ARG B NE  1 
ATOM   3779  C CZ  . ARG B 2 303 ? 187.460 123.716 150.021 1.00 110.66 ? 325 ARG B CZ  1 
ATOM   3780  N NH1 . ARG B 2 303 ? 186.206 123.302 149.902 1.00 110.66 ? 325 ARG B NH1 1 
ATOM   3781  N NH2 . ARG B 2 303 ? 187.796 124.519 151.022 1.00 110.66 ? 325 ARG B NH2 1 
ATOM   3782  N N   . PRO B 2 304 ? 185.631 122.335 142.312 1.00 117.58 ? 326 PRO B N   1 
ATOM   3783  C CA  . PRO B 2 304 ? 185.341 121.357 141.256 1.00 117.58 ? 326 PRO B CA  1 
ATOM   3784  C C   . PRO B 2 304 ? 186.617 120.862 140.593 1.00 117.58 ? 326 PRO B C   1 
ATOM   3785  O O   . PRO B 2 304 ? 187.721 121.212 141.024 1.00 117.58 ? 326 PRO B O   1 
ATOM   3786  C CB  . PRO B 2 304 ? 184.461 122.141 140.270 1.00 117.58 ? 326 PRO B CB  1 
ATOM   3787  C CG  . PRO B 2 304 ? 184.112 123.433 140.971 1.00 117.58 ? 326 PRO B CG  1 
ATOM   3788  C CD  . PRO B 2 304 ? 185.240 123.693 141.909 1.00 117.58 ? 326 PRO B CD  1 
ATOM   3789  N N   . SER B 2 305 ? 186.483 120.051 139.545 1.00 134.05 ? 327 SER B N   1 
ATOM   3790  C CA  . SER B 2 305 ? 187.634 119.513 138.838 1.00 134.05 ? 327 SER B CA  1 
ATOM   3791  C C   . SER B 2 305 ? 187.380 119.560 137.339 1.00 134.05 ? 327 SER B C   1 
ATOM   3792  O O   . SER B 2 305 ? 186.255 119.356 136.876 1.00 134.05 ? 327 SER B O   1 
ATOM   3793  C CB  . SER B 2 305 ? 187.942 118.074 139.274 1.00 134.05 ? 327 SER B CB  1 
ATOM   3794  O OG  . SER B 2 305 ? 188.692 118.055 140.476 1.00 134.05 ? 327 SER B OG  1 
ATOM   3795  N N   . LYS B 2 306 ? 188.443 119.833 136.584 1.00 176.39 ? 328 LYS B N   1 
ATOM   3796  C CA  . LYS B 2 306 ? 188.388 119.905 135.132 1.00 176.39 ? 328 LYS B CA  1 
ATOM   3797  C C   . LYS B 2 306 ? 189.433 118.969 134.539 1.00 176.39 ? 328 LYS B C   1 
ATOM   3798  O O   . LYS B 2 306 ? 190.276 118.410 135.245 1.00 176.39 ? 328 LYS B O   1 
ATOM   3799  C CB  . LYS B 2 306 ? 188.610 121.340 134.632 1.00 176.39 ? 328 LYS B CB  1 
ATOM   3800  C CG  . LYS B 2 306 ? 187.333 122.069 134.244 1.00 176.39 ? 328 LYS B CG  1 
ATOM   3801  C CD  . LYS B 2 306 ? 186.458 122.346 135.456 1.00 176.39 ? 328 LYS B CD  1 
ATOM   3802  C CE  . LYS B 2 306 ? 185.172 123.053 135.059 1.00 176.39 ? 328 LYS B CE  1 
ATOM   3803  N NZ  . LYS B 2 306 ? 184.283 123.289 136.230 1.00 176.39 ? 328 LYS B NZ  1 
ATOM   3804  N N   . ALA B 2 307 ? 189.370 118.802 133.216 1.00 229.78 ? 329 ALA B N   1 
ATOM   3805  C CA  . ALA B 2 307 ? 190.290 117.908 132.520 1.00 229.78 ? 329 ALA B CA  1 
ATOM   3806  C C   . ALA B 2 307 ? 191.520 118.678 132.053 1.00 229.78 ? 329 ALA B C   1 
ATOM   3807  O O   . ALA B 2 307 ? 191.382 119.684 131.347 1.00 229.78 ? 329 ALA B O   1 
ATOM   3808  C CB  . ALA B 2 307 ? 189.610 117.254 131.326 1.00 229.78 ? 329 ALA B CB  1 
ATOM   3809  N N   . PRO B 2 308 ? 192.720 118.245 132.420 1.00 213.93 ? 330 PRO B N   1 
ATOM   3810  C CA  . PRO B 2 308 ? 193.939 118.936 131.992 1.00 213.93 ? 330 PRO B CA  1 
ATOM   3811  C C   . PRO B 2 308 ? 194.366 118.484 130.599 1.00 213.93 ? 330 PRO B C   1 
ATOM   3812  O O   . PRO B 2 308 ? 193.697 117.693 129.937 1.00 213.93 ? 330 PRO B O   1 
ATOM   3813  C CB  . PRO B 2 308 ? 194.956 118.520 133.054 1.00 213.93 ? 330 PRO B CB  1 
ATOM   3814  C CG  . PRO B 2 308 ? 194.515 117.151 133.453 1.00 213.93 ? 330 PRO B CG  1 
ATOM   3815  C CD  . PRO B 2 308 ? 193.009 117.129 133.337 1.00 213.93 ? 330 PRO B CD  1 
ATOM   3816  N N   . SER B 2 309 ? 195.509 119.008 130.162 1.00 218.39 ? 331 SER B N   1 
ATOM   3817  C CA  . SER B 2 309 ? 196.105 118.662 128.880 1.00 218.39 ? 331 SER B CA  1 
ATOM   3818  C C   . SER B 2 309 ? 197.481 118.054 129.109 1.00 218.39 ? 331 SER B C   1 
ATOM   3819  O O   . SER B 2 309 ? 198.257 118.546 129.934 1.00 218.39 ? 331 SER B O   1 
ATOM   3820  C CB  . SER B 2 309 ? 196.218 119.890 127.970 1.00 218.39 ? 331 SER B CB  1 
ATOM   3821  O OG  . SER B 2 309 ? 197.276 120.736 128.385 1.00 218.39 ? 331 SER B OG  1 
ATOM   3822  N N   . PHE B 2 310 ? 197.781 116.985 128.374 1.00 207.49 ? 332 PHE B N   1 
ATOM   3823  C CA  . PHE B 2 310 ? 199.027 116.253 128.545 1.00 207.49 ? 332 PHE B CA  1 
ATOM   3824  C C   . PHE B 2 310 ? 199.602 115.890 127.185 1.00 207.49 ? 332 PHE B C   1 
ATOM   3825  O O   . PHE B 2 310 ? 198.858 115.620 126.239 1.00 207.49 ? 332 PHE B O   1 
ATOM   3826  C CB  . PHE B 2 310 ? 198.812 114.984 129.381 1.00 207.49 ? 332 PHE B CB  1 
ATOM   3827  C CG  . PHE B 2 310 ? 200.064 114.189 129.613 1.00 207.49 ? 332 PHE B CG  1 
ATOM   3828  C CD1 . PHE B 2 310 ? 200.964 114.562 130.597 1.00 207.49 ? 332 PHE B CD1 1 
ATOM   3829  C CD2 . PHE B 2 310 ? 200.337 113.065 128.852 1.00 207.49 ? 332 PHE B CD2 1 
ATOM   3830  C CE1 . PHE B 2 310 ? 202.115 113.831 130.814 1.00 207.49 ? 332 PHE B CE1 1 
ATOM   3831  C CE2 . PHE B 2 310 ? 201.487 112.330 129.065 1.00 207.49 ? 332 PHE B CE2 1 
ATOM   3832  C CZ  . PHE B 2 310 ? 202.376 112.714 130.047 1.00 207.49 ? 332 PHE B CZ  1 
ATOM   3833  N N   . TRP B 2 311 ? 200.931 115.884 127.096 1.00 213.01 ? 333 TRP B N   1 
ATOM   3834  C CA  . TRP B 2 311 ? 201.623 115.512 125.871 1.00 213.01 ? 333 TRP B CA  1 
ATOM   3835  C C   . TRP B 2 311 ? 203.033 115.058 126.217 1.00 213.01 ? 333 TRP B C   1 
ATOM   3836  O O   . TRP B 2 311 ? 203.620 115.505 127.205 1.00 213.01 ? 333 TRP B O   1 
ATOM   3837  C CB  . TRP B 2 311 ? 201.664 116.674 124.869 1.00 213.01 ? 333 TRP B CB  1 
ATOM   3838  C CG  . TRP B 2 311 ? 202.385 116.344 123.597 1.00 213.01 ? 333 TRP B CG  1 
ATOM   3839  C CD1 . TRP B 2 311 ? 203.550 116.894 123.150 1.00 213.01 ? 333 TRP B CD1 1 
ATOM   3840  C CD2 . TRP B 2 311 ? 201.991 115.382 122.611 1.00 213.01 ? 333 TRP B CD2 1 
ATOM   3841  N NE1 . TRP B 2 311 ? 203.905 116.337 121.946 1.00 213.01 ? 333 TRP B NE1 1 
ATOM   3842  C CE2 . TRP B 2 311 ? 202.965 115.406 121.593 1.00 213.01 ? 333 TRP B CE2 1 
ATOM   3843  C CE3 . TRP B 2 311 ? 200.910 114.504 122.490 1.00 213.01 ? 333 TRP B CE3 1 
ATOM   3844  C CZ2 . TRP B 2 311 ? 202.889 114.586 120.469 1.00 213.01 ? 333 TRP B CZ2 1 
ATOM   3845  C CZ3 . TRP B 2 311 ? 200.837 113.691 121.373 1.00 213.01 ? 333 TRP B CZ3 1 
ATOM   3846  C CH2 . TRP B 2 311 ? 201.821 113.738 120.378 1.00 213.01 ? 333 TRP B CH2 1 
ATOM   3847  N N   . TYR B 2 312 ? 203.570 114.162 125.391 1.00 197.63 ? 334 TYR B N   1 
ATOM   3848  C CA  . TYR B 2 312 ? 204.894 113.596 125.594 1.00 197.63 ? 334 TYR B CA  1 
ATOM   3849  C C   . TYR B 2 312 ? 205.801 113.948 124.422 1.00 197.63 ? 334 TYR B C   1 
ATOM   3850  O O   . TYR B 2 312 ? 205.340 114.258 123.320 1.00 197.63 ? 334 TYR B O   1 
ATOM   3851  C CB  . TYR B 2 312 ? 204.825 112.072 125.759 1.00 197.63 ? 334 TYR B CB  1 
ATOM   3852  C CG  . TYR B 2 312 ? 204.681 111.325 124.452 1.00 197.63 ? 334 TYR B CG  1 
ATOM   3853  C CD1 . TYR B 2 312 ? 203.471 111.307 123.770 1.00 197.63 ? 334 TYR B CD1 1 
ATOM   3854  C CD2 . TYR B 2 312 ? 205.754 110.637 123.901 1.00 197.63 ? 334 TYR B CD2 1 
ATOM   3855  C CE1 . TYR B 2 312 ? 203.335 110.627 122.575 1.00 197.63 ? 334 TYR B CE1 1 
ATOM   3856  C CE2 . TYR B 2 312 ? 205.626 109.954 122.706 1.00 197.63 ? 334 TYR B CE2 1 
ATOM   3857  C CZ  . TYR B 2 312 ? 204.415 109.952 122.049 1.00 197.63 ? 334 TYR B CZ  1 
ATOM   3858  O OH  . TYR B 2 312 ? 204.285 109.272 120.860 1.00 197.63 ? 334 TYR B OH  1 
ATOM   3859  N N   . LYS B 2 313 ? 207.108 113.893 124.676 1.00 192.50 ? 335 LYS B N   1 
ATOM   3860  C CA  . LYS B 2 313 ? 208.117 114.171 123.664 1.00 192.50 ? 335 LYS B CA  1 
ATOM   3861  C C   . LYS B 2 313 ? 209.282 113.209 123.841 1.00 192.50 ? 335 LYS B C   1 
ATOM   3862  O O   . LYS B 2 313 ? 209.647 112.867 124.969 1.00 192.50 ? 335 LYS B O   1 
ATOM   3863  C CB  . LYS B 2 313 ? 208.616 115.620 123.749 1.00 192.50 ? 335 LYS B CB  1 
ATOM   3864  C CG  . LYS B 2 313 ? 207.585 116.664 123.348 1.00 192.50 ? 335 LYS B CG  1 
ATOM   3865  C CD  . LYS B 2 313 ? 208.106 118.073 123.577 1.00 192.50 ? 335 LYS B CD  1 
ATOM   3866  C CE  . LYS B 2 313 ? 207.045 119.112 123.254 1.00 192.50 ? 335 LYS B CE  1 
ATOM   3867  N NZ  . LYS B 2 313 ? 207.503 120.490 123.580 1.00 192.50 ? 335 LYS B NZ  1 
ATOM   3868  N N   . ILE B 2 314 ? 209.867 112.783 122.723 1.00 190.29 ? 336 ILE B N   1 
ATOM   3869  C CA  . ILE B 2 314 ? 210.972 111.833 122.715 1.00 190.29 ? 336 ILE B CA  1 
ATOM   3870  C C   . ILE B 2 314 ? 212.187 112.502 122.087 1.00 190.29 ? 336 ILE B C   1 
ATOM   3871  O O   . ILE B 2 314 ? 212.067 113.207 121.079 1.00 190.29 ? 336 ILE B O   1 
ATOM   3872  C CB  . ILE B 2 314 ? 210.607 110.541 121.954 1.00 190.29 ? 336 ILE B CB  1 
ATOM   3873  C CG1 . ILE B 2 314 ? 209.282 109.974 122.466 1.00 190.29 ? 336 ILE B CG1 1 
ATOM   3874  C CG2 . ILE B 2 314 ? 211.713 109.507 122.091 1.00 190.29 ? 336 ILE B CG2 1 
ATOM   3875  C CD1 . ILE B 2 314 ? 208.876 108.680 121.796 1.00 190.29 ? 336 ILE B CD1 1 
ATOM   3876  N N   . ASP B 2 315 ? 213.380 112.276 122.699 1.00 204.09 ? 337 ASP B N   1 
ATOM   3877  C CA  . ASP B 2 315 ? 214.606 112.863 122.182 1.00 204.09 ? 337 ASP B CA  1 
ATOM   3878  C C   . ASP B 2 315 ? 215.290 111.914 121.200 1.00 204.09 ? 337 ASP B C   1 
ATOM   3879  O O   . ASP B 2 315 ? 215.147 110.692 121.304 1.00 204.09 ? 337 ASP B O   1 
ATOM   3880  C CB  . ASP B 2 315 ? 215.562 113.198 123.326 1.00 204.09 ? 337 ASP B CB  1 
ATOM   3881  C CG  . ASP B 2 315 ? 216.139 111.962 123.992 1.00 204.09 ? 337 ASP B CG  1 
ATOM   3882  O OD1 . ASP B 2 315 ? 215.440 110.929 124.057 1.00 204.09 ? 337 ASP B OD1 1 
ATOM   3883  O OD2 . ASP B 2 315 ? 217.297 112.025 124.455 1.00 204.09 ? 337 ASP B OD2 1 
ATOM   3884  N N   . PRO B 2 316 ? 216.030 112.453 120.226 1.00 201.13 ? 338 PRO B N   1 
ATOM   3885  C CA  . PRO B 2 316 ? 216.737 111.577 119.277 1.00 201.13 ? 338 PRO B CA  1 
ATOM   3886  C C   . PRO B 2 316 ? 217.893 110.812 119.897 1.00 201.13 ? 338 PRO B C   1 
ATOM   3887  O O   . PRO B 2 316 ? 218.313 109.797 119.329 1.00 201.13 ? 338 PRO B O   1 
ATOM   3888  C CB  . PRO B 2 316 ? 217.232 112.551 118.196 1.00 201.13 ? 338 PRO B CB  1 
ATOM   3889  C CG  . PRO B 2 316 ? 216.423 113.801 118.387 1.00 201.13 ? 338 PRO B CG  1 
ATOM   3890  C CD  . PRO B 2 316 ? 216.139 113.872 119.852 1.00 201.13 ? 338 PRO B CD  1 
ATOM   3891  N N   . SER B 2 317 ? 218.420 111.260 121.035 1.00 209.79 ? 339 SER B N   1 
ATOM   3892  C CA  . SER B 2 317 ? 219.542 110.592 121.693 1.00 209.79 ? 339 SER B CA  1 
ATOM   3893  C C   . SER B 2 317 ? 218.996 109.434 122.519 1.00 209.79 ? 339 SER B C   1 
ATOM   3894  O O   . SER B 2 317 ? 218.610 109.591 123.679 1.00 209.79 ? 339 SER B O   1 
ATOM   3895  C CB  . SER B 2 317 ? 220.324 111.574 122.556 1.00 209.79 ? 339 SER B CB  1 
ATOM   3896  O OG  . SER B 2 317 ? 219.452 112.385 123.324 1.00 209.79 ? 339 SER B OG  1 
ATOM   3897  N N   . HIS B 2 318 ? 218.964 108.252 121.912 1.00 227.80 ? 340 HIS B N   1 
ATOM   3898  C CA  . HIS B 2 318 ? 218.438 107.053 122.550 1.00 227.80 ? 340 HIS B CA  1 
ATOM   3899  C C   . HIS B 2 318 ? 219.575 106.255 123.173 1.00 227.80 ? 340 HIS B C   1 
ATOM   3900  O O   . HIS B 2 318 ? 220.557 105.929 122.497 1.00 227.80 ? 340 HIS B O   1 
ATOM   3901  C CB  . HIS B 2 318 ? 217.678 106.188 121.544 1.00 227.80 ? 340 HIS B CB  1 
ATOM   3902  C CG  . HIS B 2 318 ? 216.400 106.801 121.065 1.00 227.80 ? 340 HIS B CG  1 
ATOM   3903  N ND1 . HIS B 2 318 ? 215.204 106.647 121.733 1.00 227.80 ? 340 HIS B ND1 1 
ATOM   3904  C CD2 . HIS B 2 318 ? 216.130 107.570 119.983 1.00 227.80 ? 340 HIS B CD2 1 
ATOM   3905  C CE1 . HIS B 2 318 ? 214.253 107.294 121.084 1.00 227.80 ? 340 HIS B CE1 1 
ATOM   3906  N NE2 . HIS B 2 318 ? 214.788 107.863 120.019 1.00 227.80 ? 340 HIS B NE2 1 
ATOM   3907  N N   . THR B 2 319 ? 219.438 105.943 124.458 1.00 275.17 ? 341 THR B N   1 
ATOM   3908  C CA  . THR B 2 319 ? 220.402 105.102 125.146 1.00 275.17 ? 341 THR B CA  1 
ATOM   3909  C C   . THR B 2 319 ? 220.213 103.645 124.726 1.00 275.17 ? 341 THR B C   1 
ATOM   3910  O O   . THR B 2 319 ? 219.139 103.233 124.279 1.00 275.17 ? 341 THR B O   1 
ATOM   3911  C CB  . THR B 2 319 ? 220.253 105.247 126.663 1.00 275.17 ? 341 THR B CB  1 
ATOM   3912  O OG1 . THR B 2 319 ? 220.039 106.625 126.991 1.00 275.17 ? 341 THR B OG1 1 
ATOM   3913  C CG2 . THR B 2 319 ? 221.507 104.765 127.381 1.00 275.17 ? 341 THR B CG2 1 
ATOM   3914  N N   . GLN B 2 320 ? 221.281 102.861 124.864 1.00 285.57 ? 342 GLN B N   1 
ATOM   3915  C CA  . GLN B 2 320 ? 221.230 101.455 124.487 1.00 285.57 ? 342 GLN B CA  1 
ATOM   3916  C C   . GLN B 2 320 ? 220.401 100.661 125.490 1.00 285.57 ? 342 GLN B C   1 
ATOM   3917  O O   . GLN B 2 320 ? 220.922 100.201 126.512 1.00 285.57 ? 342 GLN B O   1 
ATOM   3918  C CB  . GLN B 2 320 ? 222.642 100.876 124.380 1.00 285.57 ? 342 GLN B CB  1 
ATOM   3919  C CG  . GLN B 2 320 ? 223.612 101.755 123.607 1.00 285.57 ? 342 GLN B CG  1 
ATOM   3920  C CD  . GLN B 2 320 ? 223.113 102.091 122.215 1.00 285.57 ? 342 GLN B CD  1 
ATOM   3921  O OE1 . GLN B 2 320 ? 222.610 101.227 121.497 1.00 285.57 ? 342 GLN B OE1 1 
ATOM   3922  N NE2 . GLN B 2 320 ? 223.248 103.354 121.827 1.00 285.57 ? 342 GLN B NE2 1 
ATOM   3923  N N   . GLY B 2 321 ? 219.110 100.497 125.205 1.00 279.98 ? 343 GLY B N   1 
ATOM   3924  C CA  . GLY B 2 321 ? 218.196 99.773  126.060 1.00 279.98 ? 343 GLY B CA  1 
ATOM   3925  C C   . GLY B 2 321 ? 217.122 100.629 126.697 1.00 279.98 ? 343 GLY B C   1 
ATOM   3926  O O   . GLY B 2 321 ? 216.114 100.085 127.167 1.00 279.98 ? 343 GLY B O   1 
ATOM   3927  N N   . TYR B 2 322 ? 217.303 101.948 126.727 1.00 272.31 ? 344 TYR B N   1 
ATOM   3928  C CA  . TYR B 2 322 ? 216.339 102.853 127.337 1.00 272.31 ? 344 TYR B CA  1 
ATOM   3929  C C   . TYR B 2 322 ? 216.219 104.111 126.489 1.00 272.31 ? 344 TYR B C   1 
ATOM   3930  O O   . TYR B 2 322 ? 217.152 104.489 125.776 1.00 272.31 ? 344 TYR B O   1 
ATOM   3931  C CB  . TYR B 2 322 ? 216.740 103.226 128.772 1.00 272.31 ? 344 TYR B CB  1 
ATOM   3932  C CG  . TYR B 2 322 ? 216.679 102.077 129.755 1.00 272.31 ? 344 TYR B CG  1 
ATOM   3933  C CD1 . TYR B 2 322 ? 215.528 101.828 130.492 1.00 272.31 ? 344 TYR B CD1 1 
ATOM   3934  C CD2 . TYR B 2 322 ? 217.774 101.245 129.950 1.00 272.31 ? 344 TYR B CD2 1 
ATOM   3935  C CE1 . TYR B 2 322 ? 215.469 100.781 131.393 1.00 272.31 ? 344 TYR B CE1 1 
ATOM   3936  C CE2 . TYR B 2 322 ? 217.724 100.196 130.849 1.00 272.31 ? 344 TYR B CE2 1 
ATOM   3937  C CZ  . TYR B 2 322 ? 216.569 99.968  131.567 1.00 272.31 ? 344 TYR B CZ  1 
ATOM   3938  O OH  . TYR B 2 322 ? 216.514 98.925  132.462 1.00 272.31 ? 344 TYR B OH  1 
ATOM   3939  N N   . ARG B 2 323 ? 215.059 104.758 126.576 1.00 245.88 ? 345 ARG B N   1 
ATOM   3940  C CA  . ARG B 2 323 ? 214.797 105.996 125.857 1.00 245.88 ? 345 ARG B CA  1 
ATOM   3941  C C   . ARG B 2 323 ? 214.358 107.072 126.839 1.00 245.88 ? 345 ARG B C   1 
ATOM   3942  O O   . ARG B 2 323 ? 213.590 106.801 127.768 1.00 245.88 ? 345 ARG B O   1 
ATOM   3943  C CB  . ARG B 2 323 ? 213.726 105.800 124.774 1.00 245.88 ? 345 ARG B CB  1 
ATOM   3944  C CG  . ARG B 2 323 ? 212.452 105.138 125.268 1.00 245.88 ? 345 ARG B CG  1 
ATOM   3945  C CD  . ARG B 2 323 ? 211.472 104.904 124.131 1.00 245.88 ? 345 ARG B CD  1 
ATOM   3946  N NE  . ARG B 2 323 ? 210.264 104.221 124.585 1.00 245.88 ? 345 ARG B NE  1 
ATOM   3947  C CZ  . ARG B 2 323 ? 209.266 103.857 123.786 1.00 245.88 ? 345 ARG B CZ  1 
ATOM   3948  N NH1 . ARG B 2 323 ? 209.330 104.109 122.485 1.00 245.88 ? 345 ARG B NH1 1 
ATOM   3949  N NH2 . ARG B 2 323 ? 208.205 103.240 124.286 1.00 245.88 ? 345 ARG B NH2 1 
ATOM   3950  N N   . THR B 2 324 ? 214.854 108.290 126.634 1.00 220.41 ? 346 THR B N   1 
ATOM   3951  C CA  . THR B 2 324 ? 214.536 109.420 127.501 1.00 220.41 ? 346 THR B CA  1 
ATOM   3952  C C   . THR B 2 324 ? 213.322 110.148 126.934 1.00 220.41 ? 346 THR B C   1 
ATOM   3953  O O   . THR B 2 324 ? 213.434 110.886 125.950 1.00 220.41 ? 346 THR B O   1 
ATOM   3954  C CB  . THR B 2 324 ? 215.731 110.361 127.627 1.00 220.41 ? 346 THR B CB  1 
ATOM   3955  O OG1 . THR B 2 324 ? 216.843 109.651 128.185 1.00 220.41 ? 346 THR B OG1 1 
ATOM   3956  C CG2 . THR B 2 324 ? 215.387 111.538 128.527 1.00 220.41 ? 346 THR B CG2 1 
ATOM   3957  N N   . VAL B 2 325 ? 212.165 109.943 127.556 1.00 211.50 ? 347 VAL B N   1 
ATOM   3958  C CA  . VAL B 2 325 ? 210.911 110.550 127.126 1.00 211.50 ? 347 VAL B CA  1 
ATOM   3959  C C   . VAL B 2 325 ? 210.482 111.546 128.192 1.00 211.50 ? 347 VAL B C   1 
ATOM   3960  O O   . VAL B 2 325 ? 210.378 111.193 129.374 1.00 211.50 ? 347 VAL B O   1 
ATOM   3961  C CB  . VAL B 2 325 ? 209.822 109.493 126.884 1.00 211.50 ? 347 VAL B CB  1 
ATOM   3962  C CG1 . VAL B 2 325 ? 208.599 110.126 126.241 1.00 211.50 ? 347 VAL B CG1 1 
ATOM   3963  C CG2 . VAL B 2 325 ? 210.365 108.374 126.009 1.00 211.50 ? 347 VAL B CG2 1 
ATOM   3964  N N   . GLN B 2 326 ? 210.239 112.786 127.779 1.00 193.43 ? 348 GLN B N   1 
ATOM   3965  C CA  . GLN B 2 326 ? 209.850 113.854 128.688 1.00 193.43 ? 348 GLN B CA  1 
ATOM   3966  C C   . GLN B 2 326 ? 208.347 114.086 128.614 1.00 193.43 ? 348 GLN B C   1 
ATOM   3967  O O   . GLN B 2 326 ? 207.744 113.990 127.541 1.00 193.43 ? 348 GLN B O   1 
ATOM   3968  C CB  . GLN B 2 326 ? 210.597 115.150 128.361 1.00 193.43 ? 348 GLN B CB  1 
ATOM   3969  C CG  . GLN B 2 326 ? 210.513 115.575 126.902 1.00 193.43 ? 348 GLN B CG  1 
ATOM   3970  C CD  . GLN B 2 326 ? 211.621 114.981 126.054 1.00 193.43 ? 348 GLN B CD  1 
ATOM   3971  O OE1 . GLN B 2 326 ? 212.328 114.069 126.484 1.00 193.43 ? 348 GLN B OE1 1 
ATOM   3972  N NE2 . GLN B 2 326 ? 211.779 115.496 124.840 1.00 193.43 ? 348 GLN B NE2 1 
ATOM   3973  N N   . LEU B 2 327 ? 207.749 114.390 129.762 1.00 192.15 ? 349 LEU B N   1 
ATOM   3974  C CA  . LEU B 2 327 ? 206.319 114.642 129.872 1.00 192.15 ? 349 LEU B CA  1 
ATOM   3975  C C   . LEU B 2 327 ? 206.093 116.101 130.238 1.00 192.15 ? 349 LEU B C   1 
ATOM   3976  O O   . LEU B 2 327 ? 206.718 116.615 131.172 1.00 192.15 ? 349 LEU B O   1 
ATOM   3977  C CB  . LEU B 2 327 ? 205.682 113.726 130.918 1.00 192.15 ? 349 LEU B CB  1 
ATOM   3978  C CG  . LEU B 2 327 ? 206.105 112.256 130.878 1.00 192.15 ? 349 LEU B CG  1 
ATOM   3979  C CD1 . LEU B 2 327 ? 205.423 111.473 131.988 1.00 192.15 ? 349 LEU B CD1 1 
ATOM   3980  C CD2 . LEU B 2 327 ? 205.801 111.642 129.520 1.00 192.15 ? 349 LEU B CD2 1 
ATOM   3981  N N   . VAL B 2 328 ? 205.202 116.763 129.505 1.00 196.45 ? 350 VAL B N   1 
ATOM   3982  C CA  . VAL B 2 328 ? 204.908 118.175 129.705 1.00 196.45 ? 350 VAL B CA  1 
ATOM   3983  C C   . VAL B 2 328 ? 203.396 118.362 129.726 1.00 196.45 ? 350 VAL B C   1 
ATOM   3984  O O   . VAL B 2 328 ? 202.670 117.724 128.957 1.00 196.45 ? 350 VAL B O   1 
ATOM   3985  C CB  . VAL B 2 328 ? 205.564 119.049 128.611 1.00 196.45 ? 350 VAL B CB  1 
ATOM   3986  C CG1 . VAL B 2 328 ? 205.154 118.576 127.223 1.00 196.45 ? 350 VAL B CG1 1 
ATOM   3987  C CG2 . VAL B 2 328 ? 205.225 120.521 128.811 1.00 196.45 ? 350 VAL B CG2 1 
ATOM   3988  N N   . TRP B 2 329 ? 202.924 119.228 130.622 1.00 183.18 ? 351 TRP B N   1 
ATOM   3989  C CA  . TRP B 2 329 ? 201.506 119.526 130.745 1.00 183.18 ? 351 TRP B CA  1 
ATOM   3990  C C   . TRP B 2 329 ? 201.331 121.016 130.995 1.00 183.18 ? 351 TRP B C   1 
ATOM   3991  O O   . TRP B 2 329 ? 202.242 121.699 131.470 1.00 183.18 ? 351 TRP B O   1 
ATOM   3992  C CB  . TRP B 2 329 ? 200.850 118.713 131.870 1.00 183.18 ? 351 TRP B CB  1 
ATOM   3993  C CG  . TRP B 2 329 ? 201.613 118.738 133.158 1.00 183.18 ? 351 TRP B CG  1 
ATOM   3994  C CD1 . TRP B 2 329 ? 201.376 119.541 134.235 1.00 183.18 ? 351 TRP B CD1 1 
ATOM   3995  C CD2 . TRP B 2 329 ? 202.736 117.920 133.506 1.00 183.18 ? 351 TRP B CD2 1 
ATOM   3996  N NE1 . TRP B 2 329 ? 202.283 119.275 135.232 1.00 183.18 ? 351 TRP B NE1 1 
ATOM   3997  C CE2 . TRP B 2 329 ? 203.129 118.283 134.809 1.00 183.18 ? 351 TRP B CE2 1 
ATOM   3998  C CE3 . TRP B 2 329 ? 203.447 116.916 132.842 1.00 183.18 ? 351 TRP B CE3 1 
ATOM   3999  C CZ2 . TRP B 2 329 ? 204.201 117.679 135.461 1.00 183.18 ? 351 TRP B CZ2 1 
ATOM   4000  C CZ3 . TRP B 2 329 ? 204.512 116.318 133.491 1.00 183.18 ? 351 TRP B CZ3 1 
ATOM   4001  C CH2 . TRP B 2 329 ? 204.878 116.701 134.786 1.00 183.18 ? 351 TRP B CH2 1 
ATOM   4002  N N   . LYS B 2 330 ? 200.144 121.516 130.669 1.00 182.17 ? 352 LYS B N   1 
ATOM   4003  C CA  . LYS B 2 330 ? 199.831 122.930 130.795 1.00 182.17 ? 352 LYS B CA  1 
ATOM   4004  C C   . LYS B 2 330 ? 199.067 123.201 132.085 1.00 182.17 ? 352 LYS B C   1 
ATOM   4005  O O   . LYS B 2 330 ? 198.369 122.331 132.613 1.00 182.17 ? 352 LYS B O   1 
ATOM   4006  C CB  . LYS B 2 330 ? 199.016 123.418 129.596 1.00 182.17 ? 352 LYS B CB  1 
ATOM   4007  C CG  . LYS B 2 330 ? 199.768 123.367 128.276 1.00 182.17 ? 352 LYS B CG  1 
ATOM   4008  C CD  . LYS B 2 330 ? 201.068 124.151 128.353 1.00 182.17 ? 352 LYS B CD  1 
ATOM   4009  C CE  . LYS B 2 330 ? 201.827 124.096 127.038 1.00 182.17 ? 352 LYS B CE  1 
ATOM   4010  N NZ  . LYS B 2 330 ? 203.123 124.827 127.115 1.00 182.17 ? 352 LYS B NZ  1 
ATOM   4011  N N   . THR B 2 331 ? 199.209 124.425 132.587 1.00 148.40 ? 353 THR B N   1 
ATOM   4012  C CA  . THR B 2 331 ? 198.534 124.818 133.815 1.00 148.40 ? 353 THR B CA  1 
ATOM   4013  C C   . THR B 2 331 ? 197.051 125.050 133.554 1.00 148.40 ? 353 THR B C   1 
ATOM   4014  O O   . THR B 2 331 ? 196.666 125.634 132.536 1.00 148.40 ? 353 THR B O   1 
ATOM   4015  C CB  . THR B 2 331 ? 199.176 126.083 134.389 1.00 148.40 ? 353 THR B CB  1 
ATOM   4016  O OG1 . THR B 2 331 ? 200.558 125.832 134.672 1.00 148.40 ? 353 THR B OG1 1 
ATOM   4017  C CG2 . THR B 2 331 ? 198.478 126.513 135.672 1.00 148.40 ? 353 THR B CG2 1 
ATOM   4018  N N   . LEU B 2 332 ? 196.216 124.584 134.478 1.00 125.86 ? 354 LEU B N   1 
ATOM   4019  C CA  . LEU B 2 332 ? 194.779 124.745 134.327 1.00 125.86 ? 354 LEU B CA  1 
ATOM   4020  C C   . LEU B 2 332 ? 194.398 126.218 134.459 1.00 125.86 ? 354 LEU B C   1 
ATOM   4021  O O   . LEU B 2 332 ? 194.938 126.926 135.315 1.00 125.86 ? 354 LEU B O   1 
ATOM   4022  C CB  . LEU B 2 332 ? 194.027 123.919 135.371 1.00 125.86 ? 354 LEU B CB  1 
ATOM   4023  C CG  . LEU B 2 332 ? 193.758 122.440 135.074 1.00 125.86 ? 354 LEU B CG  1 
ATOM   4024  C CD1 . LEU B 2 332 ? 192.879 122.288 133.839 1.00 125.86 ? 354 LEU B CD1 1 
ATOM   4025  C CD2 . LEU B 2 332 ? 195.049 121.643 134.927 1.00 125.86 ? 354 LEU B CD2 1 
ATOM   4026  N N   . PRO B 2 333 ? 193.483 126.708 133.628 1.00 120.04 ? 355 PRO B N   1 
ATOM   4027  C CA  . PRO B 2 333 ? 193.050 128.107 133.731 1.00 120.04 ? 355 PRO B CA  1 
ATOM   4028  C C   . PRO B 2 333 ? 192.333 128.358 135.044 1.00 120.04 ? 355 PRO B C   1 
ATOM   4029  O O   . PRO B 2 333 ? 191.846 127.414 135.685 1.00 120.04 ? 355 PRO B O   1 
ATOM   4030  C CB  . PRO B 2 333 ? 192.098 128.272 132.535 1.00 120.04 ? 355 PRO B CB  1 
ATOM   4031  C CG  . PRO B 2 333 ? 192.451 127.159 131.601 1.00 120.04 ? 355 PRO B CG  1 
ATOM   4032  C CD  . PRO B 2 333 ? 192.870 126.023 132.479 1.00 120.04 ? 355 PRO B CD  1 
ATOM   4033  N N   . PRO B 2 334 ? 192.255 129.616 135.485 1.00 118.76 ? 356 PRO B N   1 
ATOM   4034  C CA  . PRO B 2 334 ? 191.555 129.903 136.749 1.00 118.76 ? 356 PRO B CA  1 
ATOM   4035  C C   . PRO B 2 334 ? 190.092 129.505 136.732 1.00 118.76 ? 356 PRO B C   1 
ATOM   4036  O O   . PRO B 2 334 ? 189.556 129.107 137.774 1.00 118.76 ? 356 PRO B O   1 
ATOM   4037  C CB  . PRO B 2 334 ? 191.725 131.421 136.906 1.00 118.76 ? 356 PRO B CB  1 
ATOM   4038  C CG  . PRO B 2 334 ? 192.918 131.763 136.073 1.00 118.76 ? 356 PRO B CG  1 
ATOM   4039  C CD  . PRO B 2 334 ? 192.879 130.820 134.911 1.00 118.76 ? 356 PRO B CD  1 
ATOM   4040  N N   . PHE B 2 335 ? 189.426 129.598 135.580 1.00 137.79 ? 357 PHE B N   1 
ATOM   4041  C CA  . PHE B 2 335 ? 188.036 129.172 135.482 1.00 137.79 ? 357 PHE B CA  1 
ATOM   4042  C C   . PHE B 2 335 ? 187.893 127.657 135.424 1.00 137.79 ? 357 PHE B C   1 
ATOM   4043  O O   . PHE B 2 335 ? 186.786 127.145 135.618 1.00 137.79 ? 357 PHE B O   1 
ATOM   4044  C CB  . PHE B 2 335 ? 187.376 129.801 134.254 1.00 137.79 ? 357 PHE B CB  1 
ATOM   4045  C CG  . PHE B 2 335 ? 187.032 131.253 134.429 1.00 137.79 ? 357 PHE B CG  1 
ATOM   4046  C CD1 . PHE B 2 335 ? 186.804 132.063 133.328 1.00 137.79 ? 357 PHE B CD1 1 
ATOM   4047  C CD2 . PHE B 2 335 ? 186.936 131.808 135.694 1.00 137.79 ? 357 PHE B CD2 1 
ATOM   4048  C CE1 . PHE B 2 335 ? 186.487 133.399 133.487 1.00 137.79 ? 357 PHE B CE1 1 
ATOM   4049  C CE2 . PHE B 2 335 ? 186.620 133.144 135.859 1.00 137.79 ? 357 PHE B CE2 1 
ATOM   4050  C CZ  . PHE B 2 335 ? 186.395 133.940 134.754 1.00 137.79 ? 357 PHE B CZ  1 
ATOM   4051  N N   . GLU B 2 336 ? 188.981 126.934 135.160 1.00 140.08 ? 358 GLU B N   1 
ATOM   4052  C CA  . GLU B 2 336 ? 188.969 125.478 135.156 1.00 140.08 ? 358 GLU B CA  1 
ATOM   4053  C C   . GLU B 2 336 ? 189.625 124.863 136.381 1.00 140.08 ? 358 GLU B C   1 
ATOM   4054  O O   . GLU B 2 336 ? 189.182 123.807 136.836 1.00 140.08 ? 358 GLU B O   1 
ATOM   4055  C CB  . GLU B 2 336 ? 189.666 124.941 133.899 1.00 140.08 ? 358 GLU B CB  1 
ATOM   4056  C CG  . GLU B 2 336 ? 189.127 125.512 132.599 1.00 140.08 ? 358 GLU B CG  1 
ATOM   4057  C CD  . GLU B 2 336 ? 189.386 124.603 131.413 1.00 140.08 ? 358 GLU B CD  1 
ATOM   4058  O OE1 . GLU B 2 336 ? 188.719 123.552 131.312 1.00 140.08 ? 358 GLU B OE1 1 
ATOM   4059  O OE2 . GLU B 2 336 ? 190.256 124.939 130.583 1.00 140.08 ? 358 GLU B OE2 1 
ATOM   4060  N N   . ALA B 2 337 ? 190.668 125.495 136.925 1.00 122.14 ? 359 ALA B N   1 
ATOM   4061  C CA  . ALA B 2 337 ? 191.283 124.983 138.144 1.00 122.14 ? 359 ALA B CA  1 
ATOM   4062  C C   . ALA B 2 337 ? 190.381 125.207 139.351 1.00 122.14 ? 359 ALA B C   1 
ATOM   4063  O O   . ALA B 2 337 ? 190.220 124.309 140.187 1.00 122.14 ? 359 ALA B O   1 
ATOM   4064  C CB  . ALA B 2 337 ? 192.646 125.638 138.362 1.00 122.14 ? 359 ALA B CB  1 
ATOM   4065  N N   . ASN B 2 338 ? 189.788 126.399 139.456 1.00 122.08 ? 360 ASN B N   1 
ATOM   4066  C CA  . ASN B 2 338 ? 188.850 126.734 140.530 1.00 122.08 ? 360 ASN B CA  1 
ATOM   4067  C C   . ASN B 2 338 ? 189.494 126.570 141.905 1.00 122.08 ? 360 ASN B C   1 
ATOM   4068  O O   . ASN B 2 338 ? 188.877 126.064 142.845 1.00 122.08 ? 360 ASN B O   1 
ATOM   4069  C CB  . ASN B 2 338 ? 187.570 125.902 140.425 1.00 122.08 ? 360 ASN B CB  1 
ATOM   4070  C CG  . ASN B 2 338 ? 186.867 126.080 139.094 1.00 122.08 ? 360 ASN B CG  1 
ATOM   4071  O OD1 . ASN B 2 338 ? 186.863 127.169 138.522 1.00 122.08 ? 360 ASN B OD1 1 
ATOM   4072  N ND2 . ASN B 2 338 ? 186.268 125.005 138.594 1.00 122.08 ? 360 ASN B ND2 1 
ATOM   4073  N N   . GLY B 2 339 ? 190.740 126.998 142.022 1.00 111.72 ? 361 GLY B N   1 
ATOM   4074  C CA  . GLY B 2 339 ? 191.456 126.889 143.276 1.00 111.72 ? 361 GLY B CA  1 
ATOM   4075  C C   . GLY B 2 339 ? 192.950 126.898 143.043 1.00 111.72 ? 361 GLY B C   1 
ATOM   4076  O O   . GLY B 2 339 ? 193.431 126.974 141.912 1.00 111.72 ? 361 GLY B O   1 
ATOM   4077  N N   . LYS B 2 340 ? 193.679 126.818 144.152 1.00 110.93 ? 362 LYS B N   1 
ATOM   4078  C CA  . LYS B 2 340 ? 195.136 126.821 144.112 1.00 110.93 ? 362 LYS B CA  1 
ATOM   4079  C C   . LYS B 2 340 ? 195.642 125.422 143.781 1.00 110.93 ? 362 LYS B C   1 
ATOM   4080  O O   . LYS B 2 340 ? 195.323 124.458 144.485 1.00 110.93 ? 362 LYS B O   1 
ATOM   4081  C CB  . LYS B 2 340 ? 195.705 127.302 145.445 1.00 110.93 ? 362 LYS B CB  1 
ATOM   4082  C CG  . LYS B 2 340 ? 197.217 127.457 145.454 1.00 110.93 ? 362 LYS B CG  1 
ATOM   4083  C CD  . LYS B 2 340 ? 197.703 128.048 146.767 1.00 110.93 ? 362 LYS B CD  1 
ATOM   4084  C CE  . LYS B 2 340 ? 199.209 128.251 146.757 1.00 110.93 ? 362 LYS B CE  1 
ATOM   4085  N NZ  . LYS B 2 340 ? 199.696 128.861 148.025 1.00 110.93 ? 362 LYS B NZ  1 
ATOM   4086  N N   . ILE B 2 341 ? 196.427 125.313 142.710 1.00 119.60 ? 363 ILE B N   1 
ATOM   4087  C CA  . ILE B 2 341 ? 196.988 124.027 142.316 1.00 119.60 ? 363 ILE B CA  1 
ATOM   4088  C C   . ILE B 2 341 ? 198.032 123.598 143.338 1.00 119.60 ? 363 ILE B C   1 
ATOM   4089  O O   . ILE B 2 341 ? 198.938 124.367 143.686 1.00 119.60 ? 363 ILE B O   1 
ATOM   4090  C CB  . ILE B 2 341 ? 197.587 124.110 140.904 1.00 119.60 ? 363 ILE B CB  1 
ATOM   4091  C CG1 . ILE B 2 341 ? 196.496 124.433 139.882 1.00 119.60 ? 363 ILE B CG1 1 
ATOM   4092  C CG2 . ILE B 2 341 ? 198.290 122.810 140.543 1.00 119.60 ? 363 ILE B CG2 1 
ATOM   4093  C CD1 . ILE B 2 341 ? 195.384 123.407 139.832 1.00 119.60 ? 363 ILE B CD1 1 
ATOM   4094  N N   . LEU B 2 342 ? 197.909 122.364 143.825 1.00 122.61 ? 364 LEU B N   1 
ATOM   4095  C CA  . LEU B 2 342 ? 198.819 121.848 144.843 1.00 122.61 ? 364 LEU B CA  1 
ATOM   4096  C C   . LEU B 2 342 ? 200.003 121.113 144.219 1.00 122.61 ? 364 LEU B C   1 
ATOM   4097  O O   . LEU B 2 342 ? 201.159 121.493 144.430 1.00 122.61 ? 364 LEU B O   1 
ATOM   4098  C CB  . LEU B 2 342 ? 198.059 120.930 145.806 1.00 122.61 ? 364 LEU B CB  1 
ATOM   4099  C CG  . LEU B 2 342 ? 196.831 121.543 146.483 1.00 122.61 ? 364 LEU B CG  1 
ATOM   4100  C CD1 . LEU B 2 342 ? 196.199 120.554 147.450 1.00 122.61 ? 364 LEU B CD1 1 
ATOM   4101  C CD2 . LEU B 2 342 ? 197.201 122.835 147.196 1.00 122.61 ? 364 LEU B CD2 1 
ATOM   4102  N N   . ASP B 2 343 ? 199.728 120.066 143.446 1.00 136.21 ? 365 ASP B N   1 
ATOM   4103  C CA  . ASP B 2 343 ? 200.781 119.274 142.824 1.00 136.21 ? 365 ASP B CA  1 
ATOM   4104  C C   . ASP B 2 343 ? 200.175 118.454 141.695 1.00 136.21 ? 365 ASP B C   1 
ATOM   4105  O O   . ASP B 2 343 ? 198.953 118.368 141.547 1.00 136.21 ? 365 ASP B O   1 
ATOM   4106  C CB  . ASP B 2 343 ? 201.479 118.369 143.845 1.00 136.21 ? 365 ASP B CB  1 
ATOM   4107  C CG  . ASP B 2 343 ? 200.498 117.617 144.721 1.00 136.21 ? 365 ASP B CG  1 
ATOM   4108  O OD1 . ASP B 2 343 ? 199.282 117.887 144.622 1.00 136.21 ? 365 ASP B OD1 1 
ATOM   4109  O OD2 . ASP B 2 343 ? 200.942 116.756 145.509 1.00 136.21 ? 365 ASP B OD2 1 
ATOM   4110  N N   . TYR B 2 344 ? 201.051 117.847 140.900 1.00 164.75 ? 366 TYR B N   1 
ATOM   4111  C CA  . TYR B 2 344 ? 200.657 117.009 139.778 1.00 164.75 ? 366 TYR B CA  1 
ATOM   4112  C C   . TYR B 2 344 ? 201.077 115.569 140.039 1.00 164.75 ? 366 TYR B C   1 
ATOM   4113  O O   . TYR B 2 344 ? 202.172 115.315 140.550 1.00 164.75 ? 366 TYR B O   1 
ATOM   4114  C CB  . TYR B 2 344 ? 201.283 117.505 138.471 1.00 164.75 ? 366 TYR B CB  1 
ATOM   4115  C CG  . TYR B 2 344 ? 200.869 118.906 138.078 1.00 164.75 ? 366 TYR B CG  1 
ATOM   4116  C CD1 . TYR B 2 344 ? 199.749 119.123 137.287 1.00 164.75 ? 366 TYR B CD1 1 
ATOM   4117  C CD2 . TYR B 2 344 ? 201.600 120.010 138.496 1.00 164.75 ? 366 TYR B CD2 1 
ATOM   4118  C CE1 . TYR B 2 344 ? 199.367 120.402 136.924 1.00 164.75 ? 366 TYR B CE1 1 
ATOM   4119  C CE2 . TYR B 2 344 ? 201.226 121.292 138.139 1.00 164.75 ? 366 TYR B CE2 1 
ATOM   4120  C CZ  . TYR B 2 344 ? 200.110 121.482 137.353 1.00 164.75 ? 366 TYR B CZ  1 
ATOM   4121  O OH  . TYR B 2 344 ? 199.734 122.756 136.995 1.00 164.75 ? 366 TYR B OH  1 
ATOM   4122  N N   . GLU B 2 345 ? 200.201 114.631 139.686 1.00 158.24 ? 367 GLU B N   1 
ATOM   4123  C CA  . GLU B 2 345 ? 200.457 113.206 139.856 1.00 158.24 ? 367 GLU B CA  1 
ATOM   4124  C C   . GLU B 2 345 ? 200.360 112.524 138.499 1.00 158.24 ? 367 GLU B C   1 
ATOM   4125  O O   . GLU B 2 345 ? 199.304 112.556 137.859 1.00 158.24 ? 367 GLU B O   1 
ATOM   4126  C CB  . GLU B 2 345 ? 199.470 112.582 140.845 1.00 158.24 ? 367 GLU B CB  1 
ATOM   4127  C CG  . GLU B 2 345 ? 199.589 111.072 140.967 1.00 158.24 ? 367 GLU B CG  1 
ATOM   4128  C CD  . GLU B 2 345 ? 198.696 110.502 142.050 1.00 158.24 ? 367 GLU B CD  1 
ATOM   4129  O OE1 . GLU B 2 345 ? 198.307 111.262 142.962 1.00 158.24 ? 367 GLU B OE1 1 
ATOM   4130  O OE2 . GLU B 2 345 ? 198.382 109.295 141.990 1.00 158.24 ? 367 GLU B OE2 1 
ATOM   4131  N N   . VAL B 2 346 ? 201.459 111.912 138.065 1.00 181.01 ? 368 VAL B N   1 
ATOM   4132  C CA  . VAL B 2 346 ? 201.528 111.201 136.795 1.00 181.01 ? 368 VAL B CA  1 
ATOM   4133  C C   . VAL B 2 346 ? 201.857 109.744 137.081 1.00 181.01 ? 368 VAL B C   1 
ATOM   4134  O O   . VAL B 2 346 ? 202.803 109.450 137.822 1.00 181.01 ? 368 VAL B O   1 
ATOM   4135  C CB  . VAL B 2 346 ? 202.571 111.824 135.849 1.00 181.01 ? 368 VAL B CB  1 
ATOM   4136  C CG1 . VAL B 2 346 ? 202.699 110.999 134.577 1.00 181.01 ? 368 VAL B CG1 1 
ATOM   4137  C CG2 . VAL B 2 346 ? 202.199 113.262 135.523 1.00 181.01 ? 368 VAL B CG2 1 
ATOM   4138  N N   . THR B 2 347 ? 201.080 108.837 136.497 1.00 190.83 ? 369 THR B N   1 
ATOM   4139  C CA  . THR B 2 347 ? 201.259 107.405 136.684 1.00 190.83 ? 369 THR B CA  1 
ATOM   4140  C C   . THR B 2 347 ? 201.713 106.763 135.380 1.00 190.83 ? 369 THR B C   1 
ATOM   4141  O O   . THR B 2 347 ? 201.192 107.078 134.306 1.00 190.83 ? 369 THR B O   1 
ATOM   4142  C CB  . THR B 2 347 ? 199.963 106.744 137.163 1.00 190.83 ? 369 THR B CB  1 
ATOM   4143  O OG1 . THR B 2 347 ? 198.979 106.807 136.123 1.00 190.83 ? 369 THR B OG1 1 
ATOM   4144  C CG2 . THR B 2 347 ? 199.430 107.453 138.400 1.00 190.83 ? 369 THR B CG2 1 
ATOM   4145  N N   . LEU B 2 348 ? 202.687 105.862 135.482 1.00 189.65 ? 370 LEU B N   1 
ATOM   4146  C CA  . LEU B 2 348 ? 203.234 105.148 134.334 1.00 189.65 ? 370 LEU B CA  1 
ATOM   4147  C C   . LEU B 2 348 ? 202.952 103.663 134.508 1.00 189.65 ? 370 LEU B C   1 
ATOM   4148  O O   . LEU B 2 348 ? 203.426 103.047 135.468 1.00 189.65 ? 370 LEU B O   1 
ATOM   4149  C CB  . LEU B 2 348 ? 204.736 105.401 134.193 1.00 189.65 ? 370 LEU B CB  1 
ATOM   4150  C CG  . LEU B 2 348 ? 205.167 106.867 134.110 1.00 189.65 ? 370 LEU B CG  1 
ATOM   4151  C CD1 . LEU B 2 348 ? 206.680 106.976 133.998 1.00 189.65 ? 370 LEU B CD1 1 
ATOM   4152  C CD2 . LEU B 2 348 ? 204.487 107.563 132.941 1.00 189.65 ? 370 LEU B CD2 1 
ATOM   4153  N N   . THR B 2 349 ? 202.184 103.094 133.581 1.00 214.32 ? 371 THR B N   1 
ATOM   4154  C CA  . THR B 2 349 ? 201.778 101.695 133.647 1.00 214.32 ? 371 THR B CA  1 
ATOM   4155  C C   . THR B 2 349 ? 202.174 101.003 132.353 1.00 214.32 ? 371 THR B C   1 
ATOM   4156  O O   . THR B 2 349 ? 201.757 101.424 131.269 1.00 214.32 ? 371 THR B O   1 
ATOM   4157  C CB  . THR B 2 349 ? 200.270 101.567 133.881 1.00 214.32 ? 371 THR B CB  1 
ATOM   4158  O OG1 . THR B 2 349 ? 199.574 102.492 133.036 1.00 214.32 ? 371 THR B OG1 1 
ATOM   4159  C CG2 . THR B 2 349 ? 199.930 101.864 135.332 1.00 214.32 ? 371 THR B CG2 1 
ATOM   4160  N N   . ARG B 2 350 ? 202.976 99.947  132.466 1.00 216.75 ? 372 ARG B N   1 
ATOM   4161  C CA  . ARG B 2 350 ? 203.363 99.147  131.317 1.00 216.75 ? 372 ARG B CA  1 
ATOM   4162  C C   . ARG B 2 350 ? 202.324 98.051  131.078 1.00 216.75 ? 372 ARG B C   1 
ATOM   4163  O O   . ARG B 2 350 ? 201.308 97.959  131.771 1.00 216.75 ? 372 ARG B O   1 
ATOM   4164  C CB  . ARG B 2 350 ? 204.760 98.562  131.524 1.00 216.75 ? 372 ARG B CB  1 
ATOM   4165  C CG  . ARG B 2 350 ? 205.547 98.331  130.242 1.00 216.75 ? 372 ARG B CG  1 
ATOM   4166  C CD  . ARG B 2 350 ? 206.847 97.589  130.510 1.00 216.75 ? 372 ARG B CD  1 
ATOM   4167  N NE  . ARG B 2 350 ? 206.621 96.259  131.066 1.00 216.75 ? 372 ARG B NE  1 
ATOM   4168  C CZ  . ARG B 2 350 ? 207.591 95.394  131.348 1.00 216.75 ? 372 ARG B CZ  1 
ATOM   4169  N NH1 . ARG B 2 350 ? 208.857 95.719  131.124 1.00 216.75 ? 372 ARG B NH1 1 
ATOM   4170  N NH2 . ARG B 2 350 ? 207.295 94.204  131.852 1.00 216.75 ? 372 ARG B NH2 1 
ATOM   4171  N N   . TRP B 2 351 ? 202.581 97.206  130.083 1.00 211.41 ? 373 TRP B N   1 
ATOM   4172  C CA  . TRP B 2 351 ? 201.670 96.118  129.728 1.00 211.41 ? 373 TRP B CA  1 
ATOM   4173  C C   . TRP B 2 351 ? 201.800 95.014  130.769 1.00 211.41 ? 373 TRP B C   1 
ATOM   4174  O O   . TRP B 2 351 ? 202.667 94.142  130.679 1.00 211.41 ? 373 TRP B O   1 
ATOM   4175  C CB  . TRP B 2 351 ? 201.968 95.603  128.325 1.00 211.41 ? 373 TRP B CB  1 
ATOM   4176  C CG  . TRP B 2 351 ? 201.082 94.470  127.902 1.00 211.41 ? 373 TRP B CG  1 
ATOM   4177  C CD1 . TRP B 2 351 ? 201.372 93.138  127.958 1.00 211.41 ? 373 TRP B CD1 1 
ATOM   4178  C CD2 . TRP B 2 351 ? 199.760 94.571  127.358 1.00 211.41 ? 373 TRP B CD2 1 
ATOM   4179  N NE1 . TRP B 2 351 ? 200.313 92.403  127.482 1.00 211.41 ? 373 TRP B NE1 1 
ATOM   4180  C CE2 . TRP B 2 351 ? 199.311 93.259  127.108 1.00 211.41 ? 373 TRP B CE2 1 
ATOM   4181  C CE3 . TRP B 2 351 ? 198.914 95.643  127.059 1.00 211.41 ? 373 TRP B CE3 1 
ATOM   4182  C CZ2 . TRP B 2 351 ? 198.053 92.991  126.572 1.00 211.41 ? 373 TRP B CZ2 1 
ATOM   4183  C CZ3 . TRP B 2 351 ? 197.666 95.374  126.527 1.00 211.41 ? 373 TRP B CZ3 1 
ATOM   4184  C CH2 . TRP B 2 351 ? 197.247 94.059  126.290 1.00 211.41 ? 373 TRP B CH2 1 
ATOM   4185  N N   . LYS B 2 352 ? 200.920 95.057  131.771 1.00 222.61 ? 374 LYS B N   1 
ATOM   4186  C CA  . LYS B 2 352 ? 200.844 94.040  132.821 1.00 222.61 ? 374 LYS B CA  1 
ATOM   4187  C C   . LYS B 2 352 ? 202.179 93.904  133.558 1.00 222.61 ? 374 LYS B C   1 
ATOM   4188  O O   . LYS B 2 352 ? 202.838 92.863  133.529 1.00 222.61 ? 374 LYS B O   1 
ATOM   4189  C CB  . LYS B 2 352 ? 200.386 92.696  132.244 1.00 222.61 ? 374 LYS B CB  1 
ATOM   4190  C CG  . LYS B 2 352 ? 199.081 92.774  131.466 1.00 222.61 ? 374 LYS B CG  1 
ATOM   4191  C CD  . LYS B 2 352 ? 198.732 91.442  130.824 1.00 222.61 ? 374 LYS B CD  1 
ATOM   4192  C CE  . LYS B 2 352 ? 197.457 91.547  130.003 1.00 222.61 ? 374 LYS B CE  1 
ATOM   4193  N NZ  . LYS B 2 352 ? 197.120 90.263  129.329 1.00 222.61 ? 374 LYS B NZ  1 
ATOM   4194  N N   . SER B 2 353 ? 202.568 94.987  134.224 1.00 231.83 ? 375 SER B N   1 
ATOM   4195  C CA  . SER B 2 353 ? 203.812 95.022  134.981 1.00 231.83 ? 375 SER B CA  1 
ATOM   4196  C C   . SER B 2 353 ? 203.614 95.926  136.192 1.00 231.83 ? 375 SER B C   1 
ATOM   4197  O O   . SER B 2 353 ? 202.486 96.278  136.550 1.00 231.83 ? 375 SER B O   1 
ATOM   4198  C CB  . SER B 2 353 ? 204.976 95.493  134.100 1.00 231.83 ? 375 SER B CB  1 
ATOM   4199  O OG  . SER B 2 353 ? 205.099 96.903  134.142 1.00 231.83 ? 375 SER B OG  1 
ATOM   4200  N N   . HIS B 2 354 ? 204.722 96.301  136.826 1.00 236.40 ? 376 HIS B N   1 
ATOM   4201  C CA  . HIS B 2 354 ? 204.665 97.134  138.019 1.00 236.40 ? 376 HIS B CA  1 
ATOM   4202  C C   . HIS B 2 354 ? 204.180 98.540  137.681 1.00 236.40 ? 376 HIS B C   1 
ATOM   4203  O O   . HIS B 2 354 ? 204.424 99.064  136.591 1.00 236.40 ? 376 HIS B O   1 
ATOM   4204  C CB  . HIS B 2 354 ? 206.039 97.201  138.687 1.00 236.40 ? 376 HIS B CB  1 
ATOM   4205  C CG  . HIS B 2 354 ? 206.073 98.055  139.915 1.00 236.40 ? 376 HIS B CG  1 
ATOM   4206  N ND1 . HIS B 2 354 ? 205.278 97.810  141.014 1.00 236.40 ? 376 HIS B ND1 1 
ATOM   4207  C CD2 . HIS B 2 354 ? 206.804 99.154  140.218 1.00 236.40 ? 376 HIS B CD2 1 
ATOM   4208  C CE1 . HIS B 2 354 ? 205.519 98.720  141.941 1.00 236.40 ? 376 HIS B CE1 1 
ATOM   4209  N NE2 . HIS B 2 354 ? 206.441 99.547  141.483 1.00 236.40 ? 376 HIS B NE2 1 
ATOM   4210  N N   . LEU B 2 355 ? 203.485 99.149  138.637 1.00 220.24 ? 377 LEU B N   1 
ATOM   4211  C CA  . LEU B 2 355 ? 202.960 100.499 138.496 1.00 220.24 ? 377 LEU B CA  1 
ATOM   4212  C C   . LEU B 2 355 ? 203.921 101.497 139.127 1.00 220.24 ? 377 LEU B C   1 
ATOM   4213  O O   . LEU B 2 355 ? 204.456 101.259 140.214 1.00 220.24 ? 377 LEU B O   1 
ATOM   4214  C CB  . LEU B 2 355 ? 201.579 100.623 139.147 1.00 220.24 ? 377 LEU B CB  1 
ATOM   4215  C CG  . LEU B 2 355 ? 200.415 99.863  138.505 1.00 220.24 ? 377 LEU B CG  1 
ATOM   4216  C CD1 . LEU B 2 355 ? 200.323 98.440  139.040 1.00 220.24 ? 377 LEU B CD1 1 
ATOM   4217  C CD2 . LEU B 2 355 ? 199.106 100.606 138.727 1.00 220.24 ? 377 LEU B CD2 1 
ATOM   4218  N N   . GLN B 2 356 ? 204.137 102.616 138.439 1.00 198.37 ? 378 GLN B N   1 
ATOM   4219  C CA  . GLN B 2 356 ? 205.037 103.666 138.899 1.00 198.37 ? 378 GLN B CA  1 
ATOM   4220  C C   . GLN B 2 356 ? 204.277 104.984 138.939 1.00 198.37 ? 378 GLN B C   1 
ATOM   4221  O O   . GLN B 2 356 ? 203.704 105.404 137.929 1.00 198.37 ? 378 GLN B O   1 
ATOM   4222  C CB  . GLN B 2 356 ? 206.262 103.778 137.988 1.00 198.37 ? 378 GLN B CB  1 
ATOM   4223  C CG  . GLN B 2 356 ? 207.085 102.505 137.895 1.00 198.37 ? 378 GLN B CG  1 
ATOM   4224  C CD  . GLN B 2 356 ? 208.310 102.665 137.016 1.00 198.37 ? 378 GLN B CD  1 
ATOM   4225  O OE1 . GLN B 2 356 ? 208.568 103.744 136.483 1.00 198.37 ? 378 GLN B OE1 1 
ATOM   4226  N NE2 . GLN B 2 356 ? 209.072 101.589 136.860 1.00 198.37 ? 378 GLN B NE2 1 
ATOM   4227  N N   . ASN B 2 357 ? 204.273 105.629 140.103 1.00 199.11 ? 379 ASN B N   1 
ATOM   4228  C CA  . ASN B 2 357 ? 203.614 106.912 140.297 1.00 199.11 ? 379 ASN B CA  1 
ATOM   4229  C C   . ASN B 2 357 ? 204.633 107.939 140.771 1.00 199.11 ? 379 ASN B C   1 
ATOM   4230  O O   . ASN B 2 357 ? 205.519 107.625 141.572 1.00 199.11 ? 379 ASN B O   1 
ATOM   4231  C CB  . ASN B 2 357 ? 202.469 106.802 141.311 1.00 199.11 ? 379 ASN B CB  1 
ATOM   4232  C CG  . ASN B 2 357 ? 201.615 105.565 141.095 1.00 199.11 ? 379 ASN B CG  1 
ATOM   4233  O OD1 . ASN B 2 357 ? 201.401 105.140 139.960 1.00 199.11 ? 379 ASN B OD1 1 
ATOM   4234  N ND2 . ASN B 2 357 ? 201.123 104.978 142.184 1.00 199.11 ? 379 ASN B ND2 1 
ATOM   4235  N N   . TYR B 2 358 ? 204.503 109.167 140.272 1.00 170.36 ? 380 TYR B N   1 
ATOM   4236  C CA  . TYR B 2 358 ? 205.420 110.244 140.615 1.00 170.36 ? 380 TYR B CA  1 
ATOM   4237  C C   . TYR B 2 358 ? 204.636 111.523 140.864 1.00 170.36 ? 380 TYR B C   1 
ATOM   4238  O O   . TYR B 2 358 ? 203.680 111.825 140.144 1.00 170.36 ? 380 TYR B O   1 
ATOM   4239  C CB  . TYR B 2 358 ? 206.455 110.474 139.506 1.00 170.36 ? 380 TYR B CB  1 
ATOM   4240  C CG  . TYR B 2 358 ? 207.223 109.233 139.115 1.00 170.36 ? 380 TYR B CG  1 
ATOM   4241  C CD1 . TYR B 2 358 ? 208.322 108.811 139.851 1.00 170.36 ? 380 TYR B CD1 1 
ATOM   4242  C CD2 . TYR B 2 358 ? 206.850 108.483 138.007 1.00 170.36 ? 380 TYR B CD2 1 
ATOM   4243  C CE1 . TYR B 2 358 ? 209.027 107.677 139.496 1.00 170.36 ? 380 TYR B CE1 1 
ATOM   4244  C CE2 . TYR B 2 358 ? 207.549 107.347 137.644 1.00 170.36 ? 380 TYR B CE2 1 
ATOM   4245  C CZ  . TYR B 2 358 ? 208.637 106.949 138.392 1.00 170.36 ? 380 TYR B CZ  1 
ATOM   4246  O OH  . TYR B 2 358 ? 209.336 105.819 138.035 1.00 170.36 ? 380 TYR B OH  1 
ATOM   4247  N N   . THR B 2 359 ? 205.048 112.269 141.885 1.00 181.64 ? 381 THR B N   1 
ATOM   4248  C CA  . THR B 2 359 ? 204.445 113.550 142.230 1.00 181.64 ? 381 THR B CA  1 
ATOM   4249  C C   . THR B 2 359 ? 205.391 114.663 141.803 1.00 181.64 ? 381 THR B C   1 
ATOM   4250  O O   . THR B 2 359 ? 206.545 114.704 142.243 1.00 181.64 ? 381 THR B O   1 
ATOM   4251  C CB  . THR B 2 359 ? 204.153 113.638 143.728 1.00 181.64 ? 381 THR B CB  1 
ATOM   4252  O OG1 . THR B 2 359 ? 203.583 112.403 144.179 1.00 181.64 ? 381 THR B OG1 1 
ATOM   4253  C CG2 . THR B 2 359 ? 203.182 114.773 144.015 1.00 181.64 ? 381 THR B CG2 1 
ATOM   4254  N N   . VAL B 2 360 ? 204.905 115.560 140.948 1.00 201.92 ? 382 VAL B N   1 
ATOM   4255  C CA  . VAL B 2 360 ? 205.707 116.642 140.390 1.00 201.92 ? 382 VAL B CA  1 
ATOM   4256  C C   . VAL B 2 360 ? 205.036 117.966 140.727 1.00 201.92 ? 382 VAL B C   1 
ATOM   4257  O O   . VAL B 2 360 ? 203.829 118.129 140.515 1.00 201.92 ? 382 VAL B O   1 
ATOM   4258  C CB  . VAL B 2 360 ? 205.882 116.490 138.867 1.00 201.92 ? 382 VAL B CB  1 
ATOM   4259  C CG1 . VAL B 2 360 ? 206.644 117.675 138.294 1.00 201.92 ? 382 VAL B CG1 1 
ATOM   4260  C CG2 . VAL B 2 360 ? 206.595 115.187 138.546 1.00 201.92 ? 382 VAL B CG2 1 
ATOM   4261  N N   . ASN B 2 361 ? 205.820 118.909 141.252 1.00 215.11 ? 383 ASN B N   1 
ATOM   4262  C CA  . ASN B 2 361 ? 205.344 120.246 141.576 1.00 215.11 ? 383 ASN B CA  1 
ATOM   4263  C C   . ASN B 2 361 ? 205.643 121.250 140.468 1.00 215.11 ? 383 ASN B C   1 
ATOM   4264  O O   . ASN B 2 361 ? 205.694 122.457 140.727 1.00 215.11 ? 383 ASN B O   1 
ATOM   4265  C CB  . ASN B 2 361 ? 205.955 120.716 142.897 1.00 215.11 ? 383 ASN B CB  1 
ATOM   4266  C CG  . ASN B 2 361 ? 205.106 121.762 143.595 1.00 215.11 ? 383 ASN B CG  1 
ATOM   4267  O OD1 . ASN B 2 361 ? 203.888 121.810 143.417 1.00 215.11 ? 383 ASN B OD1 1 
ATOM   4268  N ND2 . ASN B 2 361 ? 205.750 122.608 144.395 1.00 215.11 ? 383 ASN B ND2 1 
ATOM   4269  N N   . ALA B 2 362 ? 205.840 120.776 139.241 1.00 195.22 ? 384 ALA B N   1 
ATOM   4270  C CA  . ALA B 2 362 ? 206.146 121.636 138.106 1.00 195.22 ? 384 ALA B CA  1 
ATOM   4271  C C   . ALA B 2 362 ? 205.309 121.171 136.919 1.00 195.22 ? 384 ALA B C   1 
ATOM   4272  O O   . ALA B 2 362 ? 204.392 120.356 137.061 1.00 195.22 ? 384 ALA B O   1 
ATOM   4273  C CB  . ALA B 2 362 ? 207.650 121.624 137.802 1.00 195.22 ? 384 ALA B CB  1 
ATOM   4274  N N   . THR B 2 363 ? 205.627 121.696 135.735 1.00 198.11 ? 385 THR B N   1 
ATOM   4275  C CA  . THR B 2 363 ? 204.910 121.361 134.512 1.00 198.11 ? 385 THR B CA  1 
ATOM   4276  C C   . THR B 2 363 ? 205.759 120.538 133.549 1.00 198.11 ? 385 THR B C   1 
ATOM   4277  O O   . THR B 2 363 ? 205.494 120.534 132.342 1.00 198.11 ? 385 THR B O   1 
ATOM   4278  C CB  . THR B 2 363 ? 204.415 122.632 133.820 1.00 198.11 ? 385 THR B CB  1 
ATOM   4279  O OG1 . THR B 2 363 ? 205.493 123.233 133.091 1.00 198.11 ? 385 THR B OG1 1 
ATOM   4280  C CG2 . THR B 2 363 ? 203.887 123.626 134.844 1.00 198.11 ? 385 THR B CG2 1 
ATOM   4281  N N   . LYS B 2 364 ? 206.773 119.838 134.055 1.00 191.41 ? 386 LYS B N   1 
ATOM   4282  C CA  . LYS B 2 364 ? 207.652 119.047 133.208 1.00 191.41 ? 386 LYS B CA  1 
ATOM   4283  C C   . LYS B 2 364 ? 208.264 117.922 134.030 1.00 191.41 ? 386 LYS B C   1 
ATOM   4284  O O   . LYS B 2 364 ? 208.698 118.139 135.165 1.00 191.41 ? 386 LYS B O   1 
ATOM   4285  C CB  . LYS B 2 364 ? 208.756 119.913 132.587 1.00 191.41 ? 386 LYS B CB  1 
ATOM   4286  C CG  . LYS B 2 364 ? 209.785 119.134 131.784 1.00 191.41 ? 386 LYS B CG  1 
ATOM   4287  C CD  . LYS B 2 364 ? 210.396 119.993 130.688 1.00 191.41 ? 386 LYS B CD  1 
ATOM   4288  C CE  . LYS B 2 364 ? 211.403 119.205 129.866 1.00 191.41 ? 386 LYS B CE  1 
ATOM   4289  N NZ  . LYS B 2 364 ? 210.777 118.587 128.664 1.00 191.41 ? 386 LYS B NZ  1 
ATOM   4290  N N   . LEU B 2 365 ? 208.292 116.724 133.451 1.00 188.25 ? 387 LEU B N   1 
ATOM   4291  C CA  . LEU B 2 365 ? 208.880 115.562 134.109 1.00 188.25 ? 387 LEU B CA  1 
ATOM   4292  C C   . LEU B 2 365 ? 209.388 114.602 133.045 1.00 188.25 ? 387 LEU B C   1 
ATOM   4293  O O   . LEU B 2 365 ? 208.603 114.110 132.230 1.00 188.25 ? 387 LEU B O   1 
ATOM   4294  C CB  . LEU B 2 365 ? 207.863 114.865 135.015 1.00 188.25 ? 387 LEU B CB  1 
ATOM   4295  C CG  . LEU B 2 365 ? 208.240 113.450 135.461 1.00 188.25 ? 387 LEU B CG  1 
ATOM   4296  C CD1 . LEU B 2 365 ? 209.301 113.493 136.551 1.00 188.25 ? 387 LEU B CD1 1 
ATOM   4297  C CD2 . LEU B 2 365 ? 207.013 112.680 135.925 1.00 188.25 ? 387 LEU B CD2 1 
ATOM   4298  N N   . THR B 2 366 ? 210.691 114.341 133.054 1.00 201.73 ? 388 THR B N   1 
ATOM   4299  C CA  . THR B 2 366 ? 211.305 113.367 132.164 1.00 201.73 ? 388 THR B CA  1 
ATOM   4300  C C   . THR B 2 366 ? 211.707 112.134 132.961 1.00 201.73 ? 388 THR B C   1 
ATOM   4301  O O   . THR B 2 366 ? 212.162 112.241 134.104 1.00 201.73 ? 388 THR B O   1 
ATOM   4302  C CB  . THR B 2 366 ? 212.524 113.958 131.447 1.00 201.73 ? 388 THR B CB  1 
ATOM   4303  O OG1 . THR B 2 366 ? 213.163 112.939 130.666 1.00 201.73 ? 388 THR B OG1 1 
ATOM   4304  C CG2 . THR B 2 366 ? 213.519 114.533 132.447 1.00 201.73 ? 388 THR B CG2 1 
ATOM   4305  N N   . VAL B 2 367 ? 211.521 110.960 132.359 1.00 226.98 ? 389 VAL B N   1 
ATOM   4306  C CA  . VAL B 2 367 ? 211.812 109.693 133.017 1.00 226.98 ? 389 VAL B CA  1 
ATOM   4307  C C   . VAL B 2 367 ? 212.474 108.755 132.019 1.00 226.98 ? 389 VAL B C   1 
ATOM   4308  O O   . VAL B 2 367 ? 212.264 108.855 130.806 1.00 226.98 ? 389 VAL B O   1 
ATOM   4309  C CB  . VAL B 2 367 ? 210.541 109.041 133.607 1.00 226.98 ? 389 VAL B CB  1 
ATOM   4310  C CG1 . VAL B 2 367 ? 210.112 109.758 134.878 1.00 226.98 ? 389 VAL B CG1 1 
ATOM   4311  C CG2 . VAL B 2 367 ? 209.419 109.047 132.581 1.00 226.98 ? 389 VAL B CG2 1 
ATOM   4312  N N   . ASN B 2 368 ? 213.284 107.838 132.542 1.00 290.49 ? 390 ASN B N   1 
ATOM   4313  C CA  . ASN B 2 368 ? 213.897 106.808 131.712 1.00 290.49 ? 390 ASN B CA  1 
ATOM   4314  C C   . ASN B 2 368 ? 212.841 105.787 131.310 1.00 290.49 ? 390 ASN B C   1 
ATOM   4315  O O   . ASN B 2 368 ? 212.221 105.152 132.170 1.00 290.49 ? 390 ASN B O   1 
ATOM   4316  C CB  . ASN B 2 368 ? 215.040 106.133 132.465 1.00 290.49 ? 390 ASN B CB  1 
ATOM   4317  C CG  . ASN B 2 368 ? 216.400 106.668 132.063 1.00 290.49 ? 390 ASN B CG  1 
ATOM   4318  O OD1 . ASN B 2 368 ? 216.685 106.843 130.877 1.00 290.49 ? 390 ASN B OD1 1 
ATOM   4319  N ND2 . ASN B 2 368 ? 217.248 106.929 133.054 1.00 290.49 ? 390 ASN B ND2 1 
ATOM   4320  N N   . LEU B 2 369 ? 212.635 105.628 130.006 1.00 253.72 ? 391 LEU B N   1 
ATOM   4321  C CA  . LEU B 2 369 ? 211.591 104.763 129.482 1.00 253.72 ? 391 LEU B CA  1 
ATOM   4322  C C   . LEU B 2 369 ? 212.221 103.616 128.703 1.00 253.72 ? 391 LEU B C   1 
ATOM   4323  O O   . LEU B 2 369 ? 213.274 103.775 128.078 1.00 253.72 ? 391 LEU B O   1 
ATOM   4324  C CB  . LEU B 2 369 ? 210.626 105.550 128.581 1.00 253.72 ? 391 LEU B CB  1 
ATOM   4325  C CG  . LEU B 2 369 ? 209.353 104.821 128.153 1.00 253.72 ? 391 LEU B CG  1 
ATOM   4326  C CD1 . LEU B 2 369 ? 208.738 104.149 129.366 1.00 253.72 ? 391 LEU B CD1 1 
ATOM   4327  C CD2 . LEU B 2 369 ? 208.360 105.768 127.502 1.00 253.72 ? 391 LEU B CD2 1 
ATOM   4328  N N   . THR B 2 370 ? 211.573 102.455 128.748 1.00 232.01 ? 392 THR B N   1 
ATOM   4329  C CA  . THR B 2 370 ? 212.053 101.280 128.039 1.00 232.01 ? 392 THR B CA  1 
ATOM   4330  C C   . THR B 2 370 ? 211.441 101.241 126.639 1.00 232.01 ? 392 THR B C   1 
ATOM   4331  O O   . THR B 2 370 ? 210.814 102.202 126.183 1.00 232.01 ? 392 THR B O   1 
ATOM   4332  C CB  . THR B 2 370 ? 211.740 100.010 128.829 1.00 232.01 ? 392 THR B CB  1 
ATOM   4333  O OG1 . THR B 2 370 ? 210.340 99.721  128.740 1.00 232.01 ? 392 THR B OG1 1 
ATOM   4334  C CG2 . THR B 2 370 ? 212.123 100.186 130.290 1.00 232.01 ? 392 THR B CG2 1 
ATOM   4335  N N   . ASN B 2 371 ? 211.616 100.122 125.941 1.00 224.97 ? 393 ASN B N   1 
ATOM   4336  C CA  . ASN B 2 371 ? 211.152 99.977  124.567 1.00 224.97 ? 393 ASN B CA  1 
ATOM   4337  C C   . ASN B 2 371 ? 209.763 99.361  124.464 1.00 224.97 ? 393 ASN B C   1 
ATOM   4338  O O   . ASN B 2 371 ? 209.290 99.124  123.347 1.00 224.97 ? 393 ASN B O   1 
ATOM   4339  C CB  . ASN B 2 371 ? 212.147 99.133  123.764 1.00 224.97 ? 393 ASN B CB  1 
ATOM   4340  C CG  . ASN B 2 371 ? 213.554 99.697  123.804 1.00 224.97 ? 393 ASN B CG  1 
ATOM   4341  O OD1 . ASN B 2 371 ? 213.747 100.906 123.924 1.00 224.97 ? 393 ASN B OD1 1 
ATOM   4342  N ND2 . ASN B 2 371 ? 214.546 98.820  123.702 1.00 224.97 ? 393 ASN B ND2 1 
ATOM   4343  N N   . ASP B 2 372 ? 209.102 99.096  125.587 1.00 209.47 ? 394 ASP B N   1 
ATOM   4344  C CA  . ASP B 2 372 ? 207.785 98.483  125.575 1.00 209.47 ? 394 ASP B CA  1 
ATOM   4345  C C   . ASP B 2 372 ? 206.702 99.550  125.418 1.00 209.47 ? 394 ASP B C   1 
ATOM   4346  O O   . ASP B 2 372 ? 206.978 100.749 125.326 1.00 209.47 ? 394 ASP B O   1 
ATOM   4347  C CB  . ASP B 2 372 ? 207.571 97.662  126.846 1.00 209.47 ? 394 ASP B CB  1 
ATOM   4348  C CG  . ASP B 2 372 ? 208.589 96.550  126.998 1.00 209.47 ? 394 ASP B CG  1 
ATOM   4349  O OD1 . ASP B 2 372 ? 209.098 96.064  125.966 1.00 209.47 ? 394 ASP B OD1 1 
ATOM   4350  O OD2 . ASP B 2 372 ? 208.881 96.161  128.149 1.00 209.47 ? 394 ASP B OD2 1 
ATOM   4351  N N   . ARG B 2 373 ? 205.448 99.106  125.383 1.00 197.71 ? 395 ARG B N   1 
ATOM   4352  C CA  . ARG B 2 373 ? 204.307 100.002 125.260 1.00 197.71 ? 395 ARG B CA  1 
ATOM   4353  C C   . ARG B 2 373 ? 203.848 100.442 126.644 1.00 197.71 ? 395 ARG B C   1 
ATOM   4354  O O   . ARG B 2 373 ? 203.662 99.609  127.538 1.00 197.71 ? 395 ARG B O   1 
ATOM   4355  C CB  . ARG B 2 373 ? 203.162 99.319  124.513 1.00 197.71 ? 395 ARG B CB  1 
ATOM   4356  C CG  . ARG B 2 373 ? 201.898 100.156 124.414 1.00 197.71 ? 395 ARG B CG  1 
ATOM   4357  C CD  . ARG B 2 373 ? 200.856 99.478  123.541 1.00 197.71 ? 395 ARG B CD  1 
ATOM   4358  N NE  . ARG B 2 373 ? 199.618 100.248 123.471 1.00 197.71 ? 395 ARG B NE  1 
ATOM   4359  C CZ  . ARG B 2 373 ? 198.584 99.930  122.699 1.00 197.71 ? 395 ARG B CZ  1 
ATOM   4360  N NH1 . ARG B 2 373 ? 198.637 98.855  121.925 1.00 197.71 ? 395 ARG B NH1 1 
ATOM   4361  N NH2 . ARG B 2 373 ? 197.496 100.689 122.699 1.00 197.71 ? 395 ARG B NH2 1 
ATOM   4362  N N   . TYR B 2 374 ? 203.663 101.748 126.816 1.00 200.48 ? 396 TYR B N   1 
ATOM   4363  C CA  . TYR B 2 374 ? 203.306 102.324 128.103 1.00 200.48 ? 396 TYR B CA  1 
ATOM   4364  C C   . TYR B 2 374 ? 202.041 103.160 127.965 1.00 200.48 ? 396 TYR B C   1 
ATOM   4365  O O   . TYR B 2 374 ? 201.649 103.562 126.866 1.00 200.48 ? 396 TYR B O   1 
ATOM   4366  C CB  . TYR B 2 374 ? 204.446 103.184 128.668 1.00 200.48 ? 396 TYR B CB  1 
ATOM   4367  C CG  . TYR B 2 374 ? 205.619 102.383 129.187 1.00 200.48 ? 396 TYR B CG  1 
ATOM   4368  C CD1 . TYR B 2 374 ? 205.884 102.304 130.548 1.00 200.48 ? 396 TYR B CD1 1 
ATOM   4369  C CD2 . TYR B 2 374 ? 206.458 101.700 128.316 1.00 200.48 ? 396 TYR B CD2 1 
ATOM   4370  C CE1 . TYR B 2 374 ? 206.954 101.571 131.026 1.00 200.48 ? 396 TYR B CE1 1 
ATOM   4371  C CE2 . TYR B 2 374 ? 207.529 100.966 128.783 1.00 200.48 ? 396 TYR B CE2 1 
ATOM   4372  C CZ  . TYR B 2 374 ? 207.774 100.905 130.139 1.00 200.48 ? 396 TYR B CZ  1 
ATOM   4373  O OH  . TYR B 2 374 ? 208.840 100.173 130.608 1.00 200.48 ? 396 TYR B OH  1 
ATOM   4374  N N   . LEU B 2 375 ? 201.404 103.417 129.106 1.00 207.65 ? 397 LEU B N   1 
ATOM   4375  C CA  . LEU B 2 375 ? 200.188 104.221 129.179 1.00 207.65 ? 397 LEU B CA  1 
ATOM   4376  C C   . LEU B 2 375 ? 200.346 105.217 130.320 1.00 207.65 ? 397 LEU B C   1 
ATOM   4377  O O   . LEU B 2 375 ? 200.449 104.820 131.485 1.00 207.65 ? 397 LEU B O   1 
ATOM   4378  C CB  . LEU B 2 375 ? 198.955 103.341 129.387 1.00 207.65 ? 397 LEU B CB  1 
ATOM   4379  C CG  . LEU B 2 375 ? 197.638 104.074 129.648 1.00 207.65 ? 397 LEU B CG  1 
ATOM   4380  C CD1 . LEU B 2 375 ? 197.297 104.998 128.489 1.00 207.65 ? 397 LEU B CD1 1 
ATOM   4381  C CD2 . LEU B 2 375 ? 196.514 103.080 129.896 1.00 207.65 ? 397 LEU B CD2 1 
ATOM   4382  N N   . ALA B 2 376 ? 200.364 106.504 129.987 1.00 188.57 ? 398 ALA B N   1 
ATOM   4383  C CA  . ALA B 2 376 ? 200.565 107.563 130.966 1.00 188.57 ? 398 ALA B CA  1 
ATOM   4384  C C   . ALA B 2 376 ? 199.246 108.257 131.281 1.00 188.57 ? 398 ALA B C   1 
ATOM   4385  O O   . ALA B 2 376 ? 198.432 108.504 130.387 1.00 188.57 ? 398 ALA B O   1 
ATOM   4386  C CB  . ALA B 2 376 ? 201.584 108.585 130.459 1.00 188.57 ? 398 ALA B CB  1 
ATOM   4387  N N   . THR B 2 377 ? 199.043 108.564 132.560 1.00 186.95 ? 399 THR B N   1 
ATOM   4388  C CA  . THR B 2 377 ? 197.869 109.287 133.026 1.00 186.95 ? 399 THR B CA  1 
ATOM   4389  C C   . THR B 2 377 ? 198.303 110.546 133.763 1.00 186.95 ? 399 THR B C   1 
ATOM   4390  O O   . THR B 2 377 ? 199.383 110.595 134.360 1.00 186.95 ? 399 THR B O   1 
ATOM   4391  C CB  . THR B 2 377 ? 197.001 108.423 133.953 1.00 186.95 ? 399 THR B CB  1 
ATOM   4392  O OG1 . THR B 2 377 ? 197.569 108.410 135.269 1.00 186.95 ? 399 THR B OG1 1 
ATOM   4393  C CG2 . THR B 2 377 ? 196.910 106.996 133.431 1.00 186.95 ? 399 THR B CG2 1 
ATOM   4394  N N   . LEU B 2 378 ? 197.450 111.567 133.719 1.00 175.43 ? 400 LEU B N   1 
ATOM   4395  C CA  . LEU B 2 378 ? 197.709 112.845 134.372 1.00 175.43 ? 400 LEU B CA  1 
ATOM   4396  C C   . LEU B 2 378 ? 196.540 113.177 135.288 1.00 175.43 ? 400 LEU B C   1 
ATOM   4397  O O   . LEU B 2 378 ? 195.404 113.317 134.822 1.00 175.43 ? 400 LEU B O   1 
ATOM   4398  C CB  . LEU B 2 378 ? 197.919 113.958 133.344 1.00 175.43 ? 400 LEU B CB  1 
ATOM   4399  C CG  . LEU B 2 378 ? 198.023 115.378 133.902 1.00 175.43 ? 400 LEU B CG  1 
ATOM   4400  C CD1 . LEU B 2 378 ? 199.232 115.512 134.815 1.00 175.43 ? 400 LEU B CD1 1 
ATOM   4401  C CD2 . LEU B 2 378 ? 198.082 116.395 132.773 1.00 175.43 ? 400 LEU B CD2 1 
ATOM   4402  N N   . THR B 2 379 ? 196.820 113.305 136.584 1.00 142.49 ? 401 THR B N   1 
ATOM   4403  C CA  . THR B 2 379 ? 195.807 113.626 137.585 1.00 142.49 ? 401 THR B CA  1 
ATOM   4404  C C   . THR B 2 379 ? 196.338 114.750 138.464 1.00 142.49 ? 401 THR B C   1 
ATOM   4405  O O   . THR B 2 379 ? 197.294 114.551 139.221 1.00 142.49 ? 401 THR B O   1 
ATOM   4406  C CB  . THR B 2 379 ? 195.451 112.402 138.431 1.00 142.49 ? 401 THR B CB  1 
ATOM   4407  O OG1 . THR B 2 379 ? 196.647 111.832 138.976 1.00 142.49 ? 401 THR B OG1 1 
ATOM   4408  C CG2 . THR B 2 379 ? 194.733 111.358 137.590 1.00 142.49 ? 401 THR B CG2 1 
ATOM   4409  N N   . VAL B 2 380 ? 195.721 115.922 138.367 1.00 129.16 ? 402 VAL B N   1 
ATOM   4410  C CA  . VAL B 2 380 ? 196.091 117.068 139.189 1.00 129.16 ? 402 VAL B CA  1 
ATOM   4411  C C   . VAL B 2 380 ? 195.297 117.015 140.487 1.00 129.16 ? 402 VAL B C   1 
ATOM   4412  O O   . VAL B 2 380 ? 194.112 116.658 140.497 1.00 129.16 ? 402 VAL B O   1 
ATOM   4413  C CB  . VAL B 2 380 ? 195.859 118.389 138.429 1.00 129.16 ? 402 VAL B CB  1 
ATOM   4414  C CG1 . VAL B 2 380 ? 194.392 118.559 138.062 1.00 129.16 ? 402 VAL B CG1 1 
ATOM   4415  C CG2 . VAL B 2 380 ? 196.353 119.575 139.248 1.00 129.16 ? 402 VAL B CG2 1 
ATOM   4416  N N   . ARG B 2 381 ? 195.956 117.349 141.591 1.00 120.52 ? 403 ARG B N   1 
ATOM   4417  C CA  . ARG B 2 381 ? 195.349 117.291 142.913 1.00 120.52 ? 403 ARG B CA  1 
ATOM   4418  C C   . ARG B 2 381 ? 194.987 118.691 143.389 1.00 120.52 ? 403 ARG B C   1 
ATOM   4419  O O   . ARG B 2 381 ? 195.749 119.643 143.195 1.00 120.52 ? 403 ARG B O   1 
ATOM   4420  C CB  . ARG B 2 381 ? 196.293 116.625 143.916 1.00 120.52 ? 403 ARG B CB  1 
ATOM   4421  C CG  . ARG B 2 381 ? 195.643 116.273 145.243 1.00 120.52 ? 403 ARG B CG  1 
ATOM   4422  C CD  . ARG B 2 381 ? 196.629 115.599 146.181 1.00 120.52 ? 403 ARG B CD  1 
ATOM   4423  N NE  . ARG B 2 381 ? 197.672 116.517 146.628 1.00 120.52 ? 403 ARG B NE  1 
ATOM   4424  C CZ  . ARG B 2 381 ? 197.579 117.283 147.710 1.00 120.52 ? 403 ARG B CZ  1 
ATOM   4425  N NH1 . ARG B 2 381 ? 196.487 117.242 148.461 1.00 120.52 ? 403 ARG B NH1 1 
ATOM   4426  N NH2 . ARG B 2 381 ? 198.578 118.089 148.042 1.00 120.52 ? 403 ARG B NH2 1 
ATOM   4427  N N   . ASN B 2 382 ? 193.817 118.809 144.017 1.00 112.24 ? 404 ASN B N   1 
ATOM   4428  C CA  . ASN B 2 382 ? 193.370 120.082 144.566 1.00 112.24 ? 404 ASN B CA  1 
ATOM   4429  C C   . ASN B 2 382 ? 193.016 119.928 146.040 1.00 112.24 ? 404 ASN B C   1 
ATOM   4430  O O   . ASN B 2 382 ? 193.304 118.892 146.648 1.00 112.24 ? 404 ASN B O   1 
ATOM   4431  C CB  . ASN B 2 382 ? 192.177 120.628 143.775 1.00 112.24 ? 404 ASN B CB  1 
ATOM   4432  C CG  . ASN B 2 382 ? 191.101 119.585 143.536 1.00 112.24 ? 404 ASN B CG  1 
ATOM   4433  O OD1 . ASN B 2 382 ? 190.879 118.700 144.360 1.00 112.24 ? 404 ASN B OD1 1 
ATOM   4434  N ND2 . ASN B 2 382 ? 190.423 119.688 142.398 1.00 112.24 ? 404 ASN B ND2 1 
ATOM   4435  N N   . LEU B 2 383 ? 192.396 120.956 146.624 1.00 104.38 ? 405 LEU B N   1 
ATOM   4436  C CA  . LEU B 2 383 ? 192.088 120.932 148.049 1.00 104.38 ? 405 LEU B CA  1 
ATOM   4437  C C   . LEU B 2 383 ? 191.007 119.917 148.403 1.00 104.38 ? 405 LEU B C   1 
ATOM   4438  O O   . LEU B 2 383 ? 190.883 119.552 149.577 1.00 104.38 ? 405 LEU B O   1 
ATOM   4439  C CB  . LEU B 2 383 ? 191.665 122.326 148.516 1.00 104.38 ? 405 LEU B CB  1 
ATOM   4440  C CG  . LEU B 2 383 ? 192.681 123.450 148.303 1.00 104.38 ? 405 LEU B CG  1 
ATOM   4441  C CD1 . LEU B 2 383 ? 192.108 124.785 148.752 1.00 104.38 ? 405 LEU B CD1 1 
ATOM   4442  C CD2 . LEU B 2 383 ? 193.978 123.148 149.036 1.00 104.38 ? 405 LEU B CD2 1 
ATOM   4443  N N   . VAL B 2 384 ? 190.225 119.455 147.428 1.00 113.70 ? 406 VAL B N   1 
ATOM   4444  C CA  . VAL B 2 384 ? 189.167 118.487 147.699 1.00 113.70 ? 406 VAL B CA  1 
ATOM   4445  C C   . VAL B 2 384 ? 189.519 117.077 147.229 1.00 113.70 ? 406 VAL B C   1 
ATOM   4446  O O   . VAL B 2 384 ? 188.967 116.104 147.767 1.00 113.70 ? 406 VAL B O   1 
ATOM   4447  C CB  . VAL B 2 384 ? 187.831 118.941 147.071 1.00 113.70 ? 406 VAL B CB  1 
ATOM   4448  C CG1 . VAL B 2 384 ? 187.812 118.665 145.573 1.00 113.70 ? 406 VAL B CG1 1 
ATOM   4449  C CG2 . VAL B 2 384 ? 186.652 118.272 147.767 1.00 113.70 ? 406 VAL B CG2 1 
ATOM   4450  N N   . GLY B 2 385 ? 190.418 116.935 146.259 1.00 124.32 ? 407 GLY B N   1 
ATOM   4451  C CA  . GLY B 2 385 ? 190.774 115.625 145.750 1.00 124.32 ? 407 GLY B CA  1 
ATOM   4452  C C   . GLY B 2 385 ? 191.597 115.684 144.481 1.00 124.32 ? 407 GLY B C   1 
ATOM   4453  O O   . GLY B 2 385 ? 192.553 116.458 144.388 1.00 124.32 ? 407 GLY B O   1 
ATOM   4454  N N   . LYS B 2 386 ? 191.237 114.866 143.494 1.00 133.73 ? 408 LYS B N   1 
ATOM   4455  C CA  . LYS B 2 386 ? 191.937 114.824 142.221 1.00 133.73 ? 408 LYS B CA  1 
ATOM   4456  C C   . LYS B 2 386 ? 190.939 114.981 141.082 1.00 133.73 ? 408 LYS B C   1 
ATOM   4457  O O   . LYS B 2 386 ? 189.740 114.738 141.239 1.00 133.73 ? 408 LYS B O   1 
ATOM   4458  C CB  . LYS B 2 386 ? 192.727 113.517 142.054 1.00 133.73 ? 408 LYS B CB  1 
ATOM   4459  C CG  . LYS B 2 386 ? 193.728 113.250 143.167 1.00 133.73 ? 408 LYS B CG  1 
ATOM   4460  C CD  . LYS B 2 386 ? 194.367 111.880 143.020 1.00 133.73 ? 408 LYS B CD  1 
ATOM   4461  C CE  . LYS B 2 386 ? 195.239 111.547 144.219 1.00 133.73 ? 408 LYS B CE  1 
ATOM   4462  N NZ  . LYS B 2 386 ? 195.915 110.229 144.067 1.00 133.73 ? 408 LYS B NZ  1 
ATOM   4463  N N   . SER B 2 387 ? 191.454 115.395 139.928 1.00 127.57 ? 409 SER B N   1 
ATOM   4464  C CA  . SER B 2 387 ? 190.639 115.578 138.738 1.00 127.57 ? 409 SER B CA  1 
ATOM   4465  C C   . SER B 2 387 ? 190.638 114.290 137.915 1.00 127.57 ? 409 SER B C   1 
ATOM   4466  O O   . SER B 2 387 ? 191.093 113.236 138.367 1.00 127.57 ? 409 SER B O   1 
ATOM   4467  C CB  . SER B 2 387 ? 191.146 116.770 137.930 1.00 127.57 ? 409 SER B CB  1 
ATOM   4468  O OG  . SER B 2 387 ? 192.139 116.370 137.002 1.00 127.57 ? 409 SER B OG  1 
ATOM   4469  N N   . ASP B 2 388 ? 190.123 114.366 136.691 1.00 136.32 ? 410 ASP B N   1 
ATOM   4470  C CA  . ASP B 2 388 ? 190.088 113.201 135.822 1.00 136.32 ? 410 ASP B CA  1 
ATOM   4471  C C   . ASP B 2 388 ? 191.486 112.878 135.300 1.00 136.32 ? 410 ASP B C   1 
ATOM   4472  O O   . ASP B 2 388 ? 192.396 113.712 135.313 1.00 136.32 ? 410 ASP B O   1 
ATOM   4473  C CB  . ASP B 2 388 ? 189.129 113.433 134.655 1.00 136.32 ? 410 ASP B CB  1 
ATOM   4474  C CG  . ASP B 2 388 ? 187.719 113.747 135.114 1.00 136.32 ? 410 ASP B CG  1 
ATOM   4475  O OD1 . ASP B 2 388 ? 187.328 113.275 136.203 1.00 136.32 ? 410 ASP B OD1 1 
ATOM   4476  O OD2 . ASP B 2 388 ? 187.001 114.466 134.388 1.00 136.32 ? 410 ASP B OD2 1 
ATOM   4477  N N   . ALA B 2 389 ? 191.648 111.642 134.836 1.00 157.27 ? 411 ALA B N   1 
ATOM   4478  C CA  . ALA B 2 389 ? 192.931 111.155 134.347 1.00 157.27 ? 411 ALA B CA  1 
ATOM   4479  C C   . ALA B 2 389 ? 193.033 111.402 132.846 1.00 157.27 ? 411 ALA B C   1 
ATOM   4480  O O   . ALA B 2 389 ? 192.159 110.979 132.081 1.00 157.27 ? 411 ALA B O   1 
ATOM   4481  C CB  . ALA B 2 389 ? 193.099 109.669 134.660 1.00 157.27 ? 411 ALA B CB  1 
ATOM   4482  N N   . ALA B 2 390 ? 194.098 112.084 132.430 1.00 174.23 ? 412 ALA B N   1 
ATOM   4483  C CA  . ALA B 2 390 ? 194.354 112.338 131.014 1.00 174.23 ? 412 ALA B CA  1 
ATOM   4484  C C   . ALA B 2 390 ? 195.002 111.097 130.416 1.00 174.23 ? 412 ALA B C   1 
ATOM   4485  O O   . ALA B 2 390 ? 196.187 110.832 130.631 1.00 174.23 ? 412 ALA B O   1 
ATOM   4486  C CB  . ALA B 2 390 ? 195.236 113.569 130.838 1.00 174.23 ? 412 ALA B CB  1 
ATOM   4487  N N   . VAL B 2 391 ? 194.223 110.332 129.659 1.00 192.57 ? 413 VAL B N   1 
ATOM   4488  C CA  . VAL B 2 391 ? 194.703 109.079 129.086 1.00 192.57 ? 413 VAL B CA  1 
ATOM   4489  C C   . VAL B 2 391 ? 195.471 109.373 127.805 1.00 192.57 ? 413 VAL B C   1 
ATOM   4490  O O   . VAL B 2 391 ? 194.968 110.058 126.906 1.00 192.57 ? 413 VAL B O   1 
ATOM   4491  C CB  . VAL B 2 391 ? 193.532 108.118 128.824 1.00 192.57 ? 413 VAL B CB  1 
ATOM   4492  C CG1 . VAL B 2 391 ? 194.025 106.853 128.138 1.00 192.57 ? 413 VAL B CG1 1 
ATOM   4493  C CG2 . VAL B 2 391 ? 192.819 107.784 130.126 1.00 192.57 ? 413 VAL B CG2 1 
ATOM   4494  N N   . LEU B 2 392 ? 196.694 108.857 127.721 1.00 192.41 ? 414 LEU B N   1 
ATOM   4495  C CA  . LEU B 2 392 ? 197.517 109.005 126.525 1.00 192.41 ? 414 LEU B CA  1 
ATOM   4496  C C   . LEU B 2 392 ? 198.450 107.809 126.438 1.00 192.41 ? 414 LEU B C   1 
ATOM   4497  O O   . LEU B 2 392 ? 199.204 107.543 127.379 1.00 192.41 ? 414 LEU B O   1 
ATOM   4498  C CB  . LEU B 2 392 ? 198.312 110.312 126.555 1.00 192.41 ? 414 LEU B CB  1 
ATOM   4499  C CG  . LEU B 2 392 ? 199.205 110.571 125.341 1.00 192.41 ? 414 LEU B CG  1 
ATOM   4500  C CD1 . LEU B 2 392 ? 198.389 110.532 124.059 1.00 192.41 ? 414 LEU B CD1 1 
ATOM   4501  C CD2 . LEU B 2 392 ? 199.928 111.900 125.478 1.00 192.41 ? 414 LEU B CD2 1 
ATOM   4502  N N   . THR B 2 393 ? 198.398 107.093 125.319 1.00 194.57 ? 415 THR B N   1 
ATOM   4503  C CA  . THR B 2 393 ? 199.187 105.883 125.137 1.00 194.57 ? 415 THR B CA  1 
ATOM   4504  C C   . THR B 2 393 ? 200.518 106.221 124.477 1.00 194.57 ? 415 THR B C   1 
ATOM   4505  O O   . THR B 2 393 ? 200.555 106.922 123.460 1.00 194.57 ? 415 THR B O   1 
ATOM   4506  C CB  . THR B 2 393 ? 198.424 104.862 124.292 1.00 194.57 ? 415 THR B CB  1 
ATOM   4507  O OG1 . THR B 2 393 ? 197.107 104.685 124.829 1.00 194.57 ? 415 THR B OG1 1 
ATOM   4508  C CG2 . THR B 2 393 ? 199.147 103.524 124.295 1.00 194.57 ? 415 THR B CG2 1 
ATOM   4509  N N   . ILE B 2 394 ? 201.605 105.720 125.057 1.00 191.28 ? 416 ILE B N   1 
ATOM   4510  C CA  . ILE B 2 394 ? 202.950 105.919 124.528 1.00 191.28 ? 416 ILE B CA  1 
ATOM   4511  C C   . ILE B 2 394 ? 203.296 104.704 123.670 1.00 191.28 ? 416 ILE B C   1 
ATOM   4512  O O   . ILE B 2 394 ? 203.378 103.586 124.206 1.00 191.28 ? 416 ILE B O   1 
ATOM   4513  C CB  . ILE B 2 394 ? 203.977 106.116 125.650 1.00 191.28 ? 416 ILE B CB  1 
ATOM   4514  C CG1 . ILE B 2 394 ? 203.632 107.356 126.477 1.00 191.28 ? 416 ILE B CG1 1 
ATOM   4515  C CG2 . ILE B 2 394 ? 205.380 106.228 125.073 1.00 191.28 ? 416 ILE B CG2 1 
ATOM   4516  C CD1 . ILE B 2 394 ? 204.598 107.623 127.610 1.00 191.28 ? 416 ILE B CD1 1 
ATOM   4517  N N   . PRO B 2 395 ? 203.501 104.863 122.366 1.00 202.37 ? 417 PRO B N   1 
ATOM   4518  C CA  . PRO B 2 395 ? 203.790 103.705 121.513 1.00 202.37 ? 417 PRO B CA  1 
ATOM   4519  C C   . PRO B 2 395 ? 205.196 103.175 121.751 1.00 202.37 ? 417 PRO B C   1 
ATOM   4520  O O   . PRO B 2 395 ? 206.042 103.808 122.385 1.00 202.37 ? 417 PRO B O   1 
ATOM   4521  C CB  . PRO B 2 395 ? 203.634 104.262 120.096 1.00 202.37 ? 417 PRO B CB  1 
ATOM   4522  C CG  . PRO B 2 395 ? 203.954 105.713 120.237 1.00 202.37 ? 417 PRO B CG  1 
ATOM   4523  C CD  . PRO B 2 395 ? 203.461 106.122 121.600 1.00 202.37 ? 417 PRO B CD  1 
ATOM   4524  N N   . ALA B 2 396 ? 205.435 101.977 121.223 1.00 225.02 ? 418 ALA B N   1 
ATOM   4525  C CA  . ALA B 2 396 ? 206.734 101.335 121.339 1.00 225.02 ? 418 ALA B CA  1 
ATOM   4526  C C   . ALA B 2 396 ? 207.706 101.923 120.318 1.00 225.02 ? 418 ALA B C   1 
ATOM   4527  O O   . ALA B 2 396 ? 207.375 102.832 119.551 1.00 225.02 ? 418 ALA B O   1 
ATOM   4528  C CB  . ALA B 2 396 ? 206.596 99.824  121.166 1.00 225.02 ? 418 ALA B CB  1 
ATOM   4529  N N   . CYS B 2 397 ? 208.930 101.392 120.306 1.00 238.61 ? 419 CYS B N   1 
ATOM   4530  C CA  . CYS B 2 397 ? 209.950 101.892 119.392 1.00 238.61 ? 419 CYS B CA  1 
ATOM   4531  C C   . CYS B 2 397 ? 209.714 101.447 117.956 1.00 238.61 ? 419 CYS B C   1 
ATOM   4532  O O   . CYS B 2 397 ? 210.193 102.110 117.029 1.00 238.61 ? 419 CYS B O   1 
ATOM   4533  C CB  . CYS B 2 397 ? 211.336 101.437 119.851 1.00 238.61 ? 419 CYS B CB  1 
ATOM   4534  S SG  . CYS B 2 397 ? 211.439 99.682  120.272 1.00 238.61 ? 419 CYS B SG  1 
ATOM   4535  N N   . ASP B 2 398 ? 208.991 100.349 117.750 1.00 241.35 ? 420 ASP B N   1 
ATOM   4536  C CA  . ASP B 2 398 ? 208.740 99.812  116.420 1.00 241.35 ? 420 ASP B CA  1 
ATOM   4537  C C   . ASP B 2 398 ? 207.338 100.124 115.913 1.00 241.35 ? 420 ASP B C   1 
ATOM   4538  O O   . ASP B 2 398 ? 206.930 99.584  114.880 1.00 241.35 ? 420 ASP B O   1 
ATOM   4539  C CB  . ASP B 2 398 ? 208.975 98.300  116.411 1.00 241.35 ? 420 ASP B CB  1 
ATOM   4540  C CG  . ASP B 2 398 ? 208.175 97.581  117.480 1.00 241.35 ? 420 ASP B CG  1 
ATOM   4541  O OD1 . ASP B 2 398 ? 207.931 98.183  118.547 1.00 241.35 ? 420 ASP B OD1 1 
ATOM   4542  O OD2 . ASP B 2 398 ? 207.792 96.414  117.254 1.00 241.35 ? 420 ASP B OD2 1 
ATOM   4543  N N   . PHE B 2 399 ? 206.594 100.979 116.610 1.00 228.83 ? 421 PHE B N   1 
ATOM   4544  C CA  . PHE B 2 399 ? 205.238 101.322 116.200 1.00 228.83 ? 421 PHE B CA  1 
ATOM   4545  C C   . PHE B 2 399 ? 205.287 102.403 115.126 1.00 228.83 ? 421 PHE B C   1 
ATOM   4546  O O   . PHE B 2 399 ? 205.857 103.477 115.343 1.00 228.83 ? 421 PHE B O   1 
ATOM   4547  C CB  . PHE B 2 399 ? 204.417 101.786 117.401 1.00 228.83 ? 421 PHE B CB  1 
ATOM   4548  C CG  . PHE B 2 399 ? 202.937 101.827 117.143 1.00 228.83 ? 421 PHE B CG  1 
ATOM   4549  C CD1 . PHE B 2 399 ? 202.169 100.680 117.257 1.00 228.83 ? 421 PHE B CD1 1 
ATOM   4550  C CD2 . PHE B 2 399 ? 202.313 103.012 116.789 1.00 228.83 ? 421 PHE B CD2 1 
ATOM   4551  C CE1 . PHE B 2 399 ? 200.808 100.713 117.020 1.00 228.83 ? 421 PHE B CE1 1 
ATOM   4552  C CE2 . PHE B 2 399 ? 200.952 103.052 116.552 1.00 228.83 ? 421 PHE B CE2 1 
ATOM   4553  C CZ  . PHE B 2 399 ? 200.199 101.901 116.668 1.00 228.83 ? 421 PHE B CZ  1 
ATOM   4554  N N   . GLN B 2 400 ? 204.690 102.118 113.972 1.00 221.56 ? 422 GLN B N   1 
ATOM   4555  C CA  . GLN B 2 400 ? 204.672 103.050 112.851 1.00 221.56 ? 422 GLN B CA  1 
ATOM   4556  C C   . GLN B 2 400 ? 203.417 103.910 112.929 1.00 221.56 ? 422 GLN B C   1 
ATOM   4557  O O   . GLN B 2 400 ? 202.300 103.385 112.993 1.00 221.56 ? 422 GLN B O   1 
ATOM   4558  C CB  . GLN B 2 400 ? 204.728 102.295 111.524 1.00 221.56 ? 422 GLN B CB  1 
ATOM   4559  C CG  . GLN B 2 400 ? 204.957 103.184 110.312 1.00 221.56 ? 422 GLN B CG  1 
ATOM   4560  C CD  . GLN B 2 400 ? 206.385 103.683 110.217 1.00 221.56 ? 422 GLN B CD  1 
ATOM   4561  O OE1 . GLN B 2 400 ? 207.292 103.125 110.835 1.00 221.56 ? 422 GLN B OE1 1 
ATOM   4562  N NE2 . GLN B 2 400 ? 206.592 104.739 109.440 1.00 221.56 ? 422 GLN B NE2 1 
ATOM   4563  N N   . ALA B 2 401 ? 203.601 105.228 112.923 1.00 216.99 ? 423 ALA B N   1 
ATOM   4564  C CA  . ALA B 2 401 ? 202.481 106.160 112.973 1.00 216.99 ? 423 ALA B CA  1 
ATOM   4565  C C   . ALA B 2 401 ? 201.832 106.253 111.598 1.00 216.99 ? 423 ALA B C   1 
ATOM   4566  O O   . ALA B 2 401 ? 202.465 106.697 110.634 1.00 216.99 ? 423 ALA B O   1 
ATOM   4567  C CB  . ALA B 2 401 ? 202.953 107.534 113.444 1.00 216.99 ? 423 ALA B CB  1 
ATOM   4568  N N   . THR B 2 402 ? 200.574 105.835 111.507 1.00 223.79 ? 424 THR B N   1 
ATOM   4569  C CA  . THR B 2 402 ? 199.825 105.829 110.257 1.00 223.79 ? 424 THR B CA  1 
ATOM   4570  C C   . THR B 2 402 ? 198.555 106.667 110.411 1.00 223.79 ? 424 THR B C   1 
ATOM   4571  O O   . THR B 2 402 ? 198.327 107.307 111.442 1.00 223.79 ? 424 THR B O   1 
ATOM   4572  C CB  . THR B 2 402 ? 199.497 104.395 109.830 1.00 223.79 ? 424 THR B CB  1 
ATOM   4573  O OG1 . THR B 2 402 ? 198.480 103.860 110.686 1.00 223.79 ? 424 THR B OG1 1 
ATOM   4574  C CG2 . THR B 2 402 ? 200.735 103.511 109.904 1.00 223.79 ? 424 THR B CG2 1 
ATOM   4575  N N   . HIS B 2 403 ? 197.723 106.647 109.366 1.00 224.66 ? 425 HIS B N   1 
ATOM   4576  C CA  . HIS B 2 403 ? 196.457 107.370 109.297 1.00 224.66 ? 425 HIS B CA  1 
ATOM   4577  C C   . HIS B 2 403 ? 196.639 108.854 109.601 1.00 224.66 ? 425 HIS B C   1 
ATOM   4578  O O   . HIS B 2 403 ? 196.218 109.325 110.666 1.00 224.66 ? 425 HIS B O   1 
ATOM   4579  C CB  . HIS B 2 403 ? 195.438 106.756 110.260 1.00 224.66 ? 425 HIS B CB  1 
ATOM   4580  C CG  . HIS B 2 403 ? 195.182 105.301 110.022 1.00 224.66 ? 425 HIS B CG  1 
ATOM   4581  N ND1 . HIS B 2 403 ? 196.020 104.311 110.490 1.00 224.66 ? 425 HIS B ND1 1 
ATOM   4582  C CD2 . HIS B 2 403 ? 194.184 104.667 109.361 1.00 224.66 ? 425 HIS B CD2 1 
ATOM   4583  C CE1 . HIS B 2 403 ? 195.547 103.131 110.131 1.00 224.66 ? 425 HIS B CE1 1 
ATOM   4584  N NE2 . HIS B 2 403 ? 194.435 103.319 109.445 1.00 224.66 ? 425 HIS B NE2 1 
ATOM   4585  N N   . PRO B 2 404 ? 197.254 109.618 108.704 1.00 194.61 ? 426 PRO B N   1 
ATOM   4586  C CA  . PRO B 2 404 ? 197.420 111.055 108.938 1.00 194.61 ? 426 PRO B CA  1 
ATOM   4587  C C   . PRO B 2 404 ? 196.159 111.828 108.569 1.00 194.61 ? 426 PRO B C   1 
ATOM   4588  O O   . PRO B 2 404 ? 195.223 111.305 107.963 1.00 194.61 ? 426 PRO B O   1 
ATOM   4589  C CB  . PRO B 2 404 ? 198.585 111.422 108.017 1.00 194.61 ? 426 PRO B CB  1 
ATOM   4590  C CG  . PRO B 2 404 ? 198.438 110.480 106.869 1.00 194.61 ? 426 PRO B CG  1 
ATOM   4591  C CD  . PRO B 2 404 ? 197.854 109.198 107.425 1.00 194.61 ? 426 PRO B CD  1 
ATOM   4592  N N   . VAL B 2 405 ? 196.154 113.104 108.953 1.00 176.41 ? 427 VAL B N   1 
ATOM   4593  C CA  . VAL B 2 405 ? 195.032 113.977 108.635 1.00 176.41 ? 427 VAL B CA  1 
ATOM   4594  C C   . VAL B 2 405 ? 195.115 114.416 107.176 1.00 176.41 ? 427 VAL B C   1 
ATOM   4595  O O   . VAL B 2 405 ? 196.142 114.270 106.508 1.00 176.41 ? 427 VAL B O   1 
ATOM   4596  C CB  . VAL B 2 405 ? 194.990 115.190 109.581 1.00 176.41 ? 427 VAL B CB  1 
ATOM   4597  C CG1 . VAL B 2 405 ? 194.821 114.732 111.022 1.00 176.41 ? 427 VAL B CG1 1 
ATOM   4598  C CG2 . VAL B 2 405 ? 196.249 116.027 109.425 1.00 176.41 ? 427 VAL B CG2 1 
ATOM   4599  N N   . MET B 2 406 ? 194.010 114.965 106.678 1.00 178.31 ? 428 MET B N   1 
ATOM   4600  C CA  . MET B 2 406 ? 193.906 115.397 105.294 1.00 178.31 ? 428 MET B CA  1 
ATOM   4601  C C   . MET B 2 406 ? 193.479 116.858 105.224 1.00 178.31 ? 428 MET B C   1 
ATOM   4602  O O   . MET B 2 406 ? 192.981 117.430 106.198 1.00 178.31 ? 428 MET B O   1 
ATOM   4603  C CB  . MET B 2 406 ? 192.910 114.526 104.514 1.00 178.31 ? 428 MET B CB  1 
ATOM   4604  C CG  . MET B 2 406 ? 193.204 113.036 104.576 1.00 178.31 ? 428 MET B CG  1 
ATOM   4605  S SD  . MET B 2 406 ? 194.856 112.626 103.981 1.00 178.31 ? 428 MET B SD  1 
ATOM   4606  C CE  . MET B 2 406 ? 194.773 113.238 102.300 1.00 178.31 ? 428 MET B CE  1 
ATOM   4607  N N   . ASP B 2 407 ? 193.687 117.452 104.048 1.00 175.41 ? 429 ASP B N   1 
ATOM   4608  C CA  . ASP B 2 407 ? 193.291 118.830 103.756 1.00 175.41 ? 429 ASP B CA  1 
ATOM   4609  C C   . ASP B 2 407 ? 193.943 119.815 104.729 1.00 175.41 ? 429 ASP B C   1 
ATOM   4610  O O   . ASP B 2 407 ? 193.277 120.512 105.498 1.00 175.41 ? 429 ASP B O   1 
ATOM   4611  C CB  . ASP B 2 407 ? 191.764 118.972 103.762 1.00 175.41 ? 429 ASP B CB  1 
ATOM   4612  C CG  . ASP B 2 407 ? 191.095 118.100 102.719 1.00 175.41 ? 429 ASP B CG  1 
ATOM   4613  O OD1 . ASP B 2 407 ? 191.720 117.841 101.669 1.00 175.41 ? 429 ASP B OD1 1 
ATOM   4614  O OD2 . ASP B 2 407 ? 189.944 117.673 102.949 1.00 175.41 ? 429 ASP B OD2 1 
ATOM   4615  N N   . LEU B 2 408 ? 195.272 119.862 104.678 1.00 159.32 ? 430 LEU B N   1 
ATOM   4616  C CA  . LEU B 2 408 ? 196.028 120.777 105.525 1.00 159.32 ? 430 LEU B CA  1 
ATOM   4617  C C   . LEU B 2 408 ? 195.894 122.200 104.996 1.00 159.32 ? 430 LEU B C   1 
ATOM   4618  O O   . LEU B 2 408 ? 196.339 122.501 103.883 1.00 159.32 ? 430 LEU B O   1 
ATOM   4619  C CB  . LEU B 2 408 ? 197.496 120.361 105.580 1.00 159.32 ? 430 LEU B CB  1 
ATOM   4620  C CG  . LEU B 2 408 ? 197.916 119.296 106.601 1.00 159.32 ? 430 LEU B CG  1 
ATOM   4621  C CD1 . LEU B 2 408 ? 197.658 119.783 108.020 1.00 159.32 ? 430 LEU B CD1 1 
ATOM   4622  C CD2 . LEU B 2 408 ? 197.233 117.956 106.351 1.00 159.32 ? 430 LEU B CD2 1 
ATOM   4623  N N   . LYS B 2 409 ? 195.281 123.075 105.791 1.00 173.30 ? 431 LYS B N   1 
ATOM   4624  C CA  . LYS B 2 409 ? 195.067 124.463 105.413 1.00 173.30 ? 431 LYS B CA  1 
ATOM   4625  C C   . LYS B 2 409 ? 195.422 125.375 106.578 1.00 173.30 ? 431 LYS B C   1 
ATOM   4626  O O   . LYS B 2 409 ? 195.237 125.020 107.745 1.00 173.30 ? 431 LYS B O   1 
ATOM   4627  C CB  . LYS B 2 409 ? 193.614 124.713 104.980 1.00 173.30 ? 431 LYS B CB  1 
ATOM   4628  C CG  . LYS B 2 409 ? 193.197 123.951 103.732 1.00 173.30 ? 431 LYS B CG  1 
ATOM   4629  C CD  . LYS B 2 409 ? 191.755 124.250 103.359 1.00 173.30 ? 431 LYS B CD  1 
ATOM   4630  C CE  . LYS B 2 409 ? 191.338 123.484 102.114 1.00 173.30 ? 431 LYS B CE  1 
ATOM   4631  N NZ  . LYS B 2 409 ? 189.938 123.795 101.714 1.00 173.30 ? 431 LYS B NZ  1 
ATOM   4632  N N   . ALA B 2 410 ? 195.934 126.559 106.248 1.00 204.26 ? 432 ALA B N   1 
ATOM   4633  C CA  . ALA B 2 410 ? 196.329 127.532 107.263 1.00 204.26 ? 432 ALA B CA  1 
ATOM   4634  C C   . ALA B 2 410 ? 196.279 128.922 106.651 1.00 204.26 ? 432 ALA B C   1 
ATOM   4635  O O   . ALA B 2 410 ? 197.012 129.203 105.697 1.00 204.26 ? 432 ALA B O   1 
ATOM   4636  C CB  . ALA B 2 410 ? 197.727 127.227 107.801 1.00 204.26 ? 432 ALA B CB  1 
ATOM   4637  N N   . PHE B 2 411 ? 195.422 129.787 107.196 1.00 248.38 ? 433 PHE B N   1 
ATOM   4638  C CA  . PHE B 2 411 ? 195.284 131.156 106.723 1.00 248.38 ? 433 PHE B CA  1 
ATOM   4639  C C   . PHE B 2 411 ? 194.814 132.023 107.881 1.00 248.38 ? 433 PHE B C   1 
ATOM   4640  O O   . PHE B 2 411 ? 193.993 131.569 108.691 1.00 248.38 ? 433 PHE B O   1 
ATOM   4641  C CB  . PHE B 2 411 ? 194.304 131.267 105.550 1.00 248.38 ? 433 PHE B CB  1 
ATOM   4642  C CG  . PHE B 2 411 ? 193.036 130.482 105.736 1.00 248.38 ? 433 PHE B CG  1 
ATOM   4643  C CD1 . PHE B 2 411 ? 192.954 129.163 105.321 1.00 248.38 ? 433 PHE B CD1 1 
ATOM   4644  C CD2 . PHE B 2 411 ? 191.924 131.066 106.318 1.00 248.38 ? 433 PHE B CD2 1 
ATOM   4645  C CE1 . PHE B 2 411 ? 191.789 128.440 105.489 1.00 248.38 ? 433 PHE B CE1 1 
ATOM   4646  C CE2 . PHE B 2 411 ? 190.756 130.348 106.488 1.00 248.38 ? 433 PHE B CE2 1 
ATOM   4647  C CZ  . PHE B 2 411 ? 190.688 129.033 106.073 1.00 248.38 ? 433 PHE B CZ  1 
ATOM   4648  N N   . PRO B 2 412 ? 195.309 133.255 107.990 1.00 265.37 ? 434 PRO B N   1 
ATOM   4649  C CA  . PRO B 2 412 ? 194.955 134.093 109.141 1.00 265.37 ? 434 PRO B CA  1 
ATOM   4650  C C   . PRO B 2 412 ? 193.554 134.673 109.025 1.00 265.37 ? 434 PRO B C   1 
ATOM   4651  O O   . PRO B 2 412 ? 193.135 135.142 107.963 1.00 265.37 ? 434 PRO B O   1 
ATOM   4652  C CB  . PRO B 2 412 ? 196.014 135.201 109.105 1.00 265.37 ? 434 PRO B CB  1 
ATOM   4653  C CG  . PRO B 2 412 ? 196.383 135.309 107.665 1.00 265.37 ? 434 PRO B CG  1 
ATOM   4654  C CD  . PRO B 2 412 ? 196.269 133.920 107.090 1.00 265.37 ? 434 PRO B CD  1 
ATOM   4655  N N   . LYS B 2 413 ? 192.827 134.633 110.140 1.00 301.42 ? 435 LYS B N   1 
ATOM   4656  C CA  . LYS B 2 413 ? 191.510 135.246 110.251 1.00 301.42 ? 435 LYS B CA  1 
ATOM   4657  C C   . LYS B 2 413 ? 191.451 136.050 111.540 1.00 301.42 ? 435 LYS B C   1 
ATOM   4658  O O   . LYS B 2 413 ? 191.733 135.518 112.619 1.00 301.42 ? 435 LYS B O   1 
ATOM   4659  C CB  . LYS B 2 413 ? 190.392 134.196 110.231 1.00 301.42 ? 435 LYS B CB  1 
ATOM   4660  C CG  . LYS B 2 413 ? 190.484 133.198 109.088 1.00 301.42 ? 435 LYS B CG  1 
ATOM   4661  C CD  . LYS B 2 413 ? 189.227 132.349 109.000 1.00 301.42 ? 435 LYS B CD  1 
ATOM   4662  C CE  . LYS B 2 413 ? 189.100 131.422 110.196 1.00 301.42 ? 435 LYS B CE  1 
ATOM   4663  N NZ  . LYS B 2 413 ? 188.658 130.057 109.797 1.00 301.42 ? 435 LYS B NZ  1 
ATOM   4664  N N   . ASP B 2 414 ? 191.085 137.328 111.421 1.00 354.28 ? 436 ASP B N   1 
ATOM   4665  C CA  . ASP B 2 414 ? 191.011 138.249 112.558 1.00 354.28 ? 436 ASP B CA  1 
ATOM   4666  C C   . ASP B 2 414 ? 192.357 138.314 113.283 1.00 354.28 ? 436 ASP B C   1 
ATOM   4667  O O   . ASP B 2 414 ? 192.448 138.136 114.499 1.00 354.28 ? 436 ASP B O   1 
ATOM   4668  C CB  . ASP B 2 414 ? 189.873 137.857 113.509 1.00 354.28 ? 436 ASP B CB  1 
ATOM   4669  C CG  . ASP B 2 414 ? 189.602 138.910 114.572 1.00 354.28 ? 436 ASP B CG  1 
ATOM   4670  O OD1 . ASP B 2 414 ? 188.827 139.849 114.292 1.00 354.28 ? 436 ASP B OD1 1 
ATOM   4671  O OD2 . ASP B 2 414 ? 190.145 138.794 115.691 1.00 354.28 ? 436 ASP B OD2 1 
ATOM   4672  N N   . ASN B 2 415 ? 193.416 138.557 112.507 1.00 336.08 ? 437 ASN B N   1 
ATOM   4673  C CA  . ASN B 2 415 ? 194.787 138.632 113.017 1.00 336.08 ? 437 ASN B CA  1 
ATOM   4674  C C   . ASN B 2 415 ? 195.174 137.372 113.790 1.00 336.08 ? 437 ASN B C   1 
ATOM   4675  O O   . ASN B 2 415 ? 195.955 137.430 114.743 1.00 336.08 ? 437 ASN B O   1 
ATOM   4676  C CB  . ASN B 2 415 ? 194.991 139.877 113.886 1.00 336.08 ? 437 ASN B CB  1 
ATOM   4677  C CG  . ASN B 2 415 ? 196.430 140.358 113.888 1.00 336.08 ? 437 ASN B CG  1 
ATOM   4678  O OD1 . ASN B 2 415 ? 197.175 140.126 112.936 1.00 336.08 ? 437 ASN B OD1 1 
ATOM   4679  N ND2 . ASN B 2 415 ? 196.827 141.031 114.961 1.00 336.08 ? 437 ASN B ND2 1 
ATOM   4680  N N   . MET B 2 416 ? 194.631 136.226 113.384 1.00 314.02 ? 438 MET B N   1 
ATOM   4681  C CA  . MET B 2 416 ? 194.885 134.966 114.069 1.00 314.02 ? 438 MET B CA  1 
ATOM   4682  C C   . MET B 2 416 ? 194.872 133.839 113.049 1.00 314.02 ? 438 MET B C   1 
ATOM   4683  O O   . MET B 2 416 ? 193.960 133.759 112.222 1.00 314.02 ? 438 MET B O   1 
ATOM   4684  C CB  . MET B 2 416 ? 193.838 134.710 115.160 1.00 314.02 ? 438 MET B CB  1 
ATOM   4685  C CG  . MET B 2 416 ? 194.074 133.440 115.961 1.00 314.02 ? 438 MET B CG  1 
ATOM   4686  S SD  . MET B 2 416 ? 195.519 133.556 117.031 1.00 314.02 ? 438 MET B SD  1 
ATOM   4687  C CE  . MET B 2 416 ? 196.586 132.325 116.290 1.00 314.02 ? 438 MET B CE  1 
ATOM   4688  N N   . LEU B 2 417 ? 195.881 132.974 113.112 1.00 284.03 ? 439 LEU B N   1 
ATOM   4689  C CA  . LEU B 2 417 ? 195.973 131.845 112.197 1.00 284.03 ? 439 LEU B CA  1 
ATOM   4690  C C   . LEU B 2 417 ? 195.035 130.732 112.644 1.00 284.03 ? 439 LEU B C   1 
ATOM   4691  O O   . LEU B 2 417 ? 195.032 130.343 113.816 1.00 284.03 ? 439 LEU B O   1 
ATOM   4692  C CB  . LEU B 2 417 ? 197.409 131.327 112.125 1.00 284.03 ? 439 LEU B CB  1 
ATOM   4693  C CG  . LEU B 2 417 ? 198.310 131.870 111.014 1.00 284.03 ? 439 LEU B CG  1 
ATOM   4694  C CD1 . LEU B 2 417 ? 197.789 131.457 109.645 1.00 284.03 ? 439 LEU B CD1 1 
ATOM   4695  C CD2 . LEU B 2 417 ? 198.441 133.380 111.111 1.00 284.03 ? 439 LEU B CD2 1 
ATOM   4696  N N   . TRP B 2 418 ? 194.238 130.223 111.709 1.00 274.63 ? 440 TRP B N   1 
ATOM   4697  C CA  . TRP B 2 418 ? 193.317 129.124 111.968 1.00 274.63 ? 440 TRP B CA  1 
ATOM   4698  C C   . TRP B 2 418 ? 193.689 127.958 111.065 1.00 274.63 ? 440 TRP B C   1 
ATOM   4699  O O   . TRP B 2 418 ? 193.631 128.077 109.836 1.00 274.63 ? 440 TRP B O   1 
ATOM   4700  C CB  . TRP B 2 418 ? 191.866 129.550 111.733 1.00 274.63 ? 440 TRP B CB  1 
ATOM   4701  C CG  . TRP B 2 418 ? 191.352 130.508 112.763 1.00 274.63 ? 440 TRP B CG  1 
ATOM   4702  C CD1 . TRP B 2 418 ? 191.719 131.812 112.925 1.00 274.63 ? 440 TRP B CD1 1 
ATOM   4703  C CD2 . TRP B 2 418 ? 190.378 130.237 113.778 1.00 274.63 ? 440 TRP B CD2 1 
ATOM   4704  N NE1 . TRP B 2 418 ? 191.033 132.370 113.976 1.00 274.63 ? 440 TRP B NE1 1 
ATOM   4705  C CE2 . TRP B 2 418 ? 190.203 131.424 114.517 1.00 274.63 ? 440 TRP B CE2 1 
ATOM   4706  C CE3 . TRP B 2 418 ? 189.635 129.106 114.133 1.00 274.63 ? 440 TRP B CE3 1 
ATOM   4707  C CZ2 . TRP B 2 418 ? 189.318 131.513 115.589 1.00 274.63 ? 440 TRP B CZ2 1 
ATOM   4708  C CZ3 . TRP B 2 418 ? 188.757 129.197 115.198 1.00 274.63 ? 440 TRP B CZ3 1 
ATOM   4709  C CH2 . TRP B 2 418 ? 188.605 130.391 115.913 1.00 274.63 ? 440 TRP B CH2 1 
ATOM   4710  N N   . VAL B 2 419 ? 194.069 126.839 111.673 1.00 227.69 ? 441 VAL B N   1 
ATOM   4711  C CA  . VAL B 2 419 ? 194.474 125.642 110.947 1.00 227.69 ? 441 VAL B CA  1 
ATOM   4712  C C   . VAL B 2 419 ? 193.307 124.665 110.951 1.00 227.69 ? 441 VAL B C   1 
ATOM   4713  O O   . VAL B 2 419 ? 192.860 124.221 112.016 1.00 227.69 ? 441 VAL B O   1 
ATOM   4714  C CB  . VAL B 2 419 ? 195.728 125.006 111.567 1.00 227.69 ? 441 VAL B CB  1 
ATOM   4715  C CG1 . VAL B 2 419 ? 196.240 123.877 110.687 1.00 227.69 ? 441 VAL B CG1 1 
ATOM   4716  C CG2 . VAL B 2 419 ? 196.806 126.059 111.778 1.00 227.69 ? 441 VAL B CG2 1 
ATOM   4717  N N   . GLU B 2 420 ? 192.812 124.331 109.763 1.00 200.37 ? 442 GLU B N   1 
ATOM   4718  C CA  . GLU B 2 420 ? 191.719 123.386 109.603 1.00 200.37 ? 442 GLU B CA  1 
ATOM   4719  C C   . GLU B 2 420 ? 192.190 122.190 108.788 1.00 200.37 ? 442 GLU B C   1 
ATOM   4720  O O   . GLU B 2 420 ? 193.089 122.304 107.949 1.00 200.37 ? 442 GLU B O   1 
ATOM   4721  C CB  . GLU B 2 420 ? 190.508 124.040 108.924 1.00 200.37 ? 442 GLU B CB  1 
ATOM   4722  C CG  . GLU B 2 420 ? 190.797 124.609 107.545 1.00 200.37 ? 442 GLU B CG  1 
ATOM   4723  C CD  . GLU B 2 420 ? 189.578 125.255 106.916 1.00 200.37 ? 442 GLU B CD  1 
ATOM   4724  O OE1 . GLU B 2 420 ? 188.521 125.304 107.579 1.00 200.37 ? 442 GLU B OE1 1 
ATOM   4725  O OE2 . GLU B 2 420 ? 189.677 125.713 105.758 1.00 200.37 ? 442 GLU B OE2 1 
ATOM   4726  N N   . TRP B 2 421 ? 191.574 121.039 109.045 1.00 200.71 ? 443 TRP B N   1 
ATOM   4727  C CA  . TRP B 2 421 ? 191.950 119.809 108.364 1.00 200.71 ? 443 TRP B CA  1 
ATOM   4728  C C   . TRP B 2 421 ? 190.774 118.846 108.403 1.00 200.71 ? 443 TRP B C   1 
ATOM   4729  O O   . TRP B 2 421 ? 189.869 118.973 109.231 1.00 200.71 ? 443 TRP B O   1 
ATOM   4730  C CB  . TRP B 2 421 ? 193.190 119.171 109.001 1.00 200.71 ? 443 TRP B CB  1 
ATOM   4731  C CG  . TRP B 2 421 ? 192.965 118.709 110.407 1.00 200.71 ? 443 TRP B CG  1 
ATOM   4732  C CD1 . TRP B 2 421 ? 192.590 117.460 110.809 1.00 200.71 ? 443 TRP B CD1 1 
ATOM   4733  C CD2 . TRP B 2 421 ? 193.096 119.491 111.600 1.00 200.71 ? 443 TRP B CD2 1 
ATOM   4734  N NE1 . TRP B 2 421 ? 192.482 117.415 112.177 1.00 200.71 ? 443 TRP B NE1 1 
ATOM   4735  C CE2 . TRP B 2 421 ? 192.787 118.650 112.687 1.00 200.71 ? 443 TRP B CE2 1 
ATOM   4736  C CE3 . TRP B 2 421 ? 193.445 120.821 111.854 1.00 200.71 ? 443 TRP B CE3 1 
ATOM   4737  C CZ2 . TRP B 2 421 ? 192.816 119.094 114.007 1.00 200.71 ? 443 TRP B CZ2 1 
ATOM   4738  C CZ3 . TRP B 2 421 ? 193.474 121.260 113.166 1.00 200.71 ? 443 TRP B CZ3 1 
ATOM   4739  C CH2 . TRP B 2 421 ? 193.161 120.399 114.225 1.00 200.71 ? 443 TRP B CH2 1 
ATOM   4740  N N   . THR B 2 422 ? 190.802 117.879 107.490 1.00 197.14 ? 444 THR B N   1 
ATOM   4741  C CA  . THR B 2 422 ? 189.775 116.848 107.443 1.00 197.14 ? 444 THR B CA  1 
ATOM   4742  C C   . THR B 2 422 ? 190.127 115.727 108.412 1.00 197.14 ? 444 THR B C   1 
ATOM   4743  O O   . THR B 2 422 ? 191.248 115.208 108.395 1.00 197.14 ? 444 THR B O   1 
ATOM   4744  C CB  . THR B 2 422 ? 189.631 116.298 106.024 1.00 197.14 ? 444 THR B CB  1 
ATOM   4745  O OG1 . THR B 2 422 ? 189.229 117.352 105.140 1.00 197.14 ? 444 THR B OG1 1 
ATOM   4746  C CG2 . THR B 2 422 ? 188.591 115.188 105.985 1.00 197.14 ? 444 THR B CG2 1 
ATOM   4747  N N   . THR B 2 423 ? 189.171 115.361 109.261 1.00 234.40 ? 445 THR B N   1 
ATOM   4748  C CA  . THR B 2 423 ? 189.412 114.311 110.237 1.00 234.40 ? 445 THR B CA  1 
ATOM   4749  C C   . THR B 2 423 ? 189.601 112.969 109.531 1.00 234.40 ? 445 THR B C   1 
ATOM   4750  O O   . THR B 2 423 ? 188.945 112.698 108.520 1.00 234.40 ? 445 THR B O   1 
ATOM   4751  C CB  . THR B 2 423 ? 188.253 114.224 111.234 1.00 234.40 ? 445 THR B CB  1 
ATOM   4752  O OG1 . THR B 2 423 ? 188.436 113.089 112.090 1.00 234.40 ? 445 THR B OG1 1 
ATOM   4753  C CG2 . THR B 2 423 ? 186.919 114.105 110.507 1.00 234.40 ? 445 THR B CG2 1 
ATOM   4754  N N   . PRO B 2 424 ? 190.501 112.121 110.023 1.00 257.98 ? 446 PRO B N   1 
ATOM   4755  C CA  . PRO B 2 424 ? 190.708 110.811 109.395 1.00 257.98 ? 446 PRO B CA  1 
ATOM   4756  C C   . PRO B 2 424 ? 189.488 109.916 109.561 1.00 257.98 ? 446 PRO B C   1 
ATOM   4757  O O   . PRO B 2 424 ? 188.542 110.217 110.291 1.00 257.98 ? 446 PRO B O   1 
ATOM   4758  C CB  . PRO B 2 424 ? 191.923 110.242 110.136 1.00 257.98 ? 446 PRO B CB  1 
ATOM   4759  C CG  . PRO B 2 424 ? 192.585 111.430 110.768 1.00 257.98 ? 446 PRO B CG  1 
ATOM   4760  C CD  . PRO B 2 424 ? 191.475 112.379 111.095 1.00 257.98 ? 446 PRO B CD  1 
ATOM   4761  N N   . ARG B 2 425 ? 189.529 108.783 108.857 1.00 302.37 ? 447 ARG B N   1 
ATOM   4762  C CA  . ARG B 2 425 ? 188.413 107.845 108.900 1.00 302.37 ? 447 ARG B CA  1 
ATOM   4763  C C   . ARG B 2 425 ? 188.325 107.134 110.244 1.00 302.37 ? 447 ARG B C   1 
ATOM   4764  O O   . ARG B 2 425 ? 187.242 106.683 110.634 1.00 302.37 ? 447 ARG B O   1 
ATOM   4765  C CB  . ARG B 2 425 ? 188.539 106.824 107.768 1.00 302.37 ? 447 ARG B CB  1 
ATOM   4766  C CG  . ARG B 2 425 ? 188.038 107.316 106.417 1.00 302.37 ? 447 ARG B CG  1 
ATOM   4767  C CD  . ARG B 2 425 ? 189.069 108.192 105.721 1.00 302.37 ? 447 ARG B CD  1 
ATOM   4768  N NE  . ARG B 2 425 ? 190.334 107.491 105.515 1.00 302.37 ? 447 ARG B NE  1 
ATOM   4769  C CZ  . ARG B 2 425 ? 191.397 108.026 104.923 1.00 302.37 ? 447 ARG B CZ  1 
ATOM   4770  N NH1 . ARG B 2 425 ? 191.351 109.274 104.476 1.00 302.37 ? 447 ARG B NH1 1 
ATOM   4771  N NH2 . ARG B 2 425 ? 192.506 107.315 104.779 1.00 302.37 ? 447 ARG B NH2 1 
ATOM   4772  N N   . GLU B 2 426 ? 189.439 107.024 110.961 1.00 303.84 ? 448 GLU B N   1 
ATOM   4773  C CA  . GLU B 2 426 ? 189.450 106.341 112.243 1.00 303.84 ? 448 GLU B CA  1 
ATOM   4774  C C   . GLU B 2 426 ? 188.849 107.228 113.331 1.00 303.84 ? 448 GLU B C   1 
ATOM   4775  O O   . GLU B 2 426 ? 188.655 108.435 113.159 1.00 303.84 ? 448 GLU B O   1 
ATOM   4776  C CB  . GLU B 2 426 ? 190.873 105.928 112.617 1.00 303.84 ? 448 GLU B CB  1 
ATOM   4777  C CG  . GLU B 2 426 ? 191.545 105.009 111.607 1.00 303.84 ? 448 GLU B CG  1 
ATOM   4778  C CD  . GLU B 2 426 ? 190.956 103.611 111.599 1.00 303.84 ? 448 GLU B CD  1 
ATOM   4779  O OE1 . GLU B 2 426 ? 189.883 103.415 110.989 1.00 303.84 ? 448 GLU B OE1 1 
ATOM   4780  O OE2 . GLU B 2 426 ? 191.567 102.705 112.204 1.00 303.84 ? 448 GLU B OE2 1 
ATOM   4781  N N   . SER B 2 427 ? 188.550 106.608 114.471 1.00 305.80 ? 449 SER B N   1 
ATOM   4782  C CA  . SER B 2 427 ? 187.976 107.313 115.615 1.00 305.80 ? 449 SER B CA  1 
ATOM   4783  C C   . SER B 2 427 ? 189.097 108.034 116.351 1.00 305.80 ? 449 SER B C   1 
ATOM   4784  O O   . SER B 2 427 ? 189.809 107.439 117.163 1.00 305.80 ? 449 SER B O   1 
ATOM   4785  C CB  . SER B 2 427 ? 187.244 106.341 116.532 1.00 305.80 ? 449 SER B CB  1 
ATOM   4786  O OG  . SER B 2 427 ? 187.113 106.873 117.839 1.00 305.80 ? 449 SER B OG  1 
ATOM   4787  N N   . VAL B 2 428 ? 189.257 109.322 116.068 1.00 276.63 ? 450 VAL B N   1 
ATOM   4788  C CA  . VAL B 2 428 ? 190.293 110.121 116.710 1.00 276.63 ? 450 VAL B CA  1 
ATOM   4789  C C   . VAL B 2 428 ? 189.878 110.441 118.140 1.00 276.63 ? 450 VAL B C   1 
ATOM   4790  O O   . VAL B 2 428 ? 188.695 110.628 118.445 1.00 276.63 ? 450 VAL B O   1 
ATOM   4791  C CB  . VAL B 2 428 ? 190.571 111.404 115.902 1.00 276.63 ? 450 VAL B CB  1 
ATOM   4792  C CG1 . VAL B 2 428 ? 191.252 111.063 114.587 1.00 276.63 ? 450 VAL B CG1 1 
ATOM   4793  C CG2 . VAL B 2 428 ? 189.278 112.168 115.656 1.00 276.63 ? 450 VAL B CG2 1 
ATOM   4794  N N   . LYS B 2 429 ? 190.867 110.499 119.031 1.00 257.91 ? 451 LYS B N   1 
ATOM   4795  C CA  . LYS B 2 429 ? 190.639 110.796 120.439 1.00 257.91 ? 451 LYS B CA  1 
ATOM   4796  C C   . LYS B 2 429 ? 190.953 112.246 120.786 1.00 257.91 ? 451 LYS B C   1 
ATOM   4797  O O   . LYS B 2 429 ? 190.108 112.946 121.351 1.00 257.91 ? 451 LYS B O   1 
ATOM   4798  C CB  . LYS B 2 429 ? 191.475 109.854 121.315 1.00 257.91 ? 451 LYS B CB  1 
ATOM   4799  C CG  . LYS B 2 429 ? 191.043 109.808 122.772 1.00 257.91 ? 451 LYS B CG  1 
ATOM   4800  C CD  . LYS B 2 429 ? 192.035 110.534 123.665 1.00 257.91 ? 451 LYS B CD  1 
ATOM   4801  C CE  . LYS B 2 429 ? 191.606 110.487 125.122 1.00 257.91 ? 451 LYS B CE  1 
ATOM   4802  N NZ  . LYS B 2 429 ? 192.555 111.222 126.003 1.00 257.91 ? 451 LYS B NZ  1 
ATOM   4803  N N   . LYS B 2 430 ? 192.155 112.713 120.453 1.00 261.23 ? 452 LYS B N   1 
ATOM   4804  C CA  . LYS B 2 430 ? 192.562 114.084 120.720 1.00 261.23 ? 452 LYS B CA  1 
ATOM   4805  C C   . LYS B 2 430 ? 193.403 114.587 119.556 1.00 261.23 ? 452 LYS B C   1 
ATOM   4806  O O   . LYS B 2 430 ? 193.682 113.858 118.600 1.00 261.23 ? 452 LYS B O   1 
ATOM   4807  C CB  . LYS B 2 430 ? 193.344 114.197 122.036 1.00 261.23 ? 452 LYS B CB  1 
ATOM   4808  C CG  . LYS B 2 430 ? 192.482 114.113 123.285 1.00 261.23 ? 452 LYS B CG  1 
ATOM   4809  C CD  . LYS B 2 430 ? 191.485 115.256 123.348 1.00 261.23 ? 452 LYS B CD  1 
ATOM   4810  C CE  . LYS B 2 430 ? 190.584 115.136 124.567 1.00 261.23 ? 452 LYS B CE  1 
ATOM   4811  N NZ  . LYS B 2 430 ? 189.790 113.877 124.546 1.00 261.23 ? 452 LYS B NZ  1 
ATOM   4812  N N   . TYR B 2 431 ? 193.806 115.852 119.645 1.00 246.29 ? 453 TYR B N   1 
ATOM   4813  C CA  . TYR B 2 431 ? 194.644 116.481 118.636 1.00 246.29 ? 453 TYR B CA  1 
ATOM   4814  C C   . TYR B 2 431 ? 195.690 117.351 119.316 1.00 246.29 ? 453 TYR B C   1 
ATOM   4815  O O   . TYR B 2 431 ? 195.401 118.024 120.309 1.00 246.29 ? 453 TYR B O   1 
ATOM   4816  C CB  . TYR B 2 431 ? 193.814 117.326 117.663 1.00 246.29 ? 453 TYR B CB  1 
ATOM   4817  C CG  . TYR B 2 431 ? 193.092 116.515 116.613 1.00 246.29 ? 453 TYR B CG  1 
ATOM   4818  C CD1 . TYR B 2 431 ? 193.770 116.010 115.511 1.00 246.29 ? 453 TYR B CD1 1 
ATOM   4819  C CD2 . TYR B 2 431 ? 191.732 116.258 116.720 1.00 246.29 ? 453 TYR B CD2 1 
ATOM   4820  C CE1 . TYR B 2 431 ? 193.114 115.268 114.548 1.00 246.29 ? 453 TYR B CE1 1 
ATOM   4821  C CE2 . TYR B 2 431 ? 191.068 115.518 115.761 1.00 246.29 ? 453 TYR B CE2 1 
ATOM   4822  C CZ  . TYR B 2 431 ? 191.763 115.026 114.677 1.00 246.29 ? 453 TYR B CZ  1 
ATOM   4823  O OH  . TYR B 2 431 ? 191.105 114.289 113.721 1.00 246.29 ? 453 TYR B OH  1 
ATOM   4824  N N   . ILE B 2 432 ? 196.905 117.332 118.775 1.00 233.34 ? 454 ILE B N   1 
ATOM   4825  C CA  . ILE B 2 432 ? 198.015 118.118 119.296 1.00 233.34 ? 454 ILE B CA  1 
ATOM   4826  C C   . ILE B 2 432 ? 198.565 118.980 118.169 1.00 233.34 ? 454 ILE B C   1 
ATOM   4827  O O   . ILE B 2 432 ? 198.681 118.526 117.025 1.00 233.34 ? 454 ILE B O   1 
ATOM   4828  C CB  . ILE B 2 432 ? 199.117 117.218 119.901 1.00 233.34 ? 454 ILE B CB  1 
ATOM   4829  C CG1 . ILE B 2 432 ? 200.265 118.065 120.453 1.00 233.34 ? 454 ILE B CG1 1 
ATOM   4830  C CG2 . ILE B 2 432 ? 199.620 116.208 118.879 1.00 233.34 ? 454 ILE B CG2 1 
ATOM   4831  C CD1 . ILE B 2 432 ? 199.855 118.972 121.590 1.00 233.34 ? 454 ILE B CD1 1 
ATOM   4832  N N   . LEU B 2 433 ? 198.883 120.232 118.489 1.00 243.04 ? 455 LEU B N   1 
ATOM   4833  C CA  . LEU B 2 433 ? 199.407 121.188 117.520 1.00 243.04 ? 455 LEU B CA  1 
ATOM   4834  C C   . LEU B 2 433 ? 200.755 121.695 118.009 1.00 243.04 ? 455 LEU B C   1 
ATOM   4835  O O   . LEU B 2 433 ? 200.834 122.348 119.055 1.00 243.04 ? 455 LEU B O   1 
ATOM   4836  C CB  . LEU B 2 433 ? 198.438 122.355 117.313 1.00 243.04 ? 455 LEU B CB  1 
ATOM   4837  C CG  . LEU B 2 433 ? 196.944 122.034 117.239 1.00 243.04 ? 455 LEU B CG  1 
ATOM   4838  C CD1 . LEU B 2 433 ? 196.142 123.301 117.000 1.00 243.04 ? 455 LEU B CD1 1 
ATOM   4839  C CD2 . LEU B 2 433 ? 196.670 121.021 116.140 1.00 243.04 ? 455 LEU B CD2 1 
ATOM   4840  N N   . GLU B 2 434 ? 201.807 121.397 117.253 1.00 225.33 ? 456 GLU B N   1 
ATOM   4841  C CA  . GLU B 2 434 ? 203.153 121.867 117.547 1.00 225.33 ? 456 GLU B CA  1 
ATOM   4842  C C   . GLU B 2 434 ? 203.565 122.882 116.491 1.00 225.33 ? 456 GLU B C   1 
ATOM   4843  O O   . GLU B 2 434 ? 203.414 122.630 115.291 1.00 225.33 ? 456 GLU B O   1 
ATOM   4844  C CB  . GLU B 2 434 ? 204.148 120.705 117.585 1.00 225.33 ? 456 GLU B CB  1 
ATOM   4845  C CG  . GLU B 2 434 ? 205.285 120.894 118.575 1.00 225.33 ? 456 GLU B CG  1 
ATOM   4846  C CD  . GLU B 2 434 ? 204.865 120.617 120.005 1.00 225.33 ? 456 GLU B CD  1 
ATOM   4847  O OE1 . GLU B 2 434 ? 203.941 119.802 120.205 1.00 225.33 ? 456 GLU B OE1 1 
ATOM   4848  O OE2 . GLU B 2 434 ? 205.459 121.213 120.928 1.00 225.33 ? 456 GLU B OE2 1 
ATOM   4849  N N   . TRP B 2 435 ? 204.084 124.023 116.937 1.00 235.44 ? 457 TRP B N   1 
ATOM   4850  C CA  . TRP B 2 435 ? 204.489 125.088 116.033 1.00 235.44 ? 457 TRP B CA  1 
ATOM   4851  C C   . TRP B 2 435 ? 205.733 125.771 116.577 1.00 235.44 ? 457 TRP B C   1 
ATOM   4852  O O   . TRP B 2 435 ? 205.879 125.941 117.791 1.00 235.44 ? 457 TRP B O   1 
ATOM   4853  C CB  . TRP B 2 435 ? 203.368 126.119 115.841 1.00 235.44 ? 457 TRP B CB  1 
ATOM   4854  C CG  . TRP B 2 435 ? 203.089 126.942 117.062 1.00 235.44 ? 457 TRP B CG  1 
ATOM   4855  C CD1 . TRP B 2 435 ? 203.619 128.162 117.367 1.00 235.44 ? 457 TRP B CD1 1 
ATOM   4856  C CD2 . TRP B 2 435 ? 202.212 126.604 118.143 1.00 235.44 ? 457 TRP B CD2 1 
ATOM   4857  N NE1 . TRP B 2 435 ? 203.126 128.605 118.570 1.00 235.44 ? 457 TRP B NE1 1 
ATOM   4858  C CE2 . TRP B 2 435 ? 202.259 127.667 119.067 1.00 235.44 ? 457 TRP B CE2 1 
ATOM   4859  C CE3 . TRP B 2 435 ? 201.389 125.508 118.418 1.00 235.44 ? 457 TRP B CE3 1 
ATOM   4860  C CZ2 . TRP B 2 435 ? 201.517 127.665 120.246 1.00 235.44 ? 457 TRP B CZ2 1 
ATOM   4861  C CZ3 . TRP B 2 435 ? 200.654 125.507 119.590 1.00 235.44 ? 457 TRP B CZ3 1 
ATOM   4862  C CH2 . TRP B 2 435 ? 200.723 126.579 120.489 1.00 235.44 ? 457 TRP B CH2 1 
ATOM   4863  N N   . CYS B 2 436 ? 206.628 126.154 115.671 1.00 242.73 ? 458 CYS B N   1 
ATOM   4864  C CA  . CYS B 2 436 ? 207.840 126.871 116.031 1.00 242.73 ? 458 CYS B CA  1 
ATOM   4865  C C   . CYS B 2 436 ? 208.168 127.870 114.933 1.00 242.73 ? 458 CYS B C   1 
ATOM   4866  O O   . CYS B 2 436 ? 207.699 127.745 113.799 1.00 242.73 ? 458 CYS B O   1 
ATOM   4867  C CB  . CYS B 2 436 ? 209.024 125.920 116.245 1.00 242.73 ? 458 CYS B CB  1 
ATOM   4868  S SG  . CYS B 2 436 ? 209.715 125.218 114.724 1.00 242.73 ? 458 CYS B SG  1 
ATOM   4869  N N   . VAL B 2 437 ? 208.979 128.862 115.281 1.00 262.02 ? 459 VAL B N   1 
ATOM   4870  C CA  . VAL B 2 437 ? 209.433 129.844 114.305 1.00 262.02 ? 459 VAL B CA  1 
ATOM   4871  C C   . VAL B 2 437 ? 210.672 129.308 113.600 1.00 262.02 ? 459 VAL B C   1 
ATOM   4872  O O   . VAL B 2 437 ? 211.532 128.663 114.215 1.00 262.02 ? 459 VAL B O   1 
ATOM   4873  C CB  . VAL B 2 437 ? 209.695 131.204 114.980 1.00 262.02 ? 459 VAL B CB  1 
ATOM   4874  C CG1 . VAL B 2 437 ? 210.942 131.160 115.853 1.00 262.02 ? 459 VAL B CG1 1 
ATOM   4875  C CG2 . VAL B 2 437 ? 209.810 132.303 113.933 1.00 262.02 ? 459 VAL B CG2 1 
ATOM   4876  N N   . LEU B 2 438 ? 210.747 129.537 112.293 1.00 277.53 ? 460 LEU B N   1 
ATOM   4877  C CA  . LEU B 2 438 ? 211.877 129.083 111.496 1.00 277.53 ? 460 LEU B CA  1 
ATOM   4878  C C   . LEU B 2 438 ? 212.961 130.152 111.487 1.00 277.53 ? 460 LEU B C   1 
ATOM   4879  O O   . LEU B 2 438 ? 212.677 131.333 111.262 1.00 277.53 ? 460 LEU B O   1 
ATOM   4880  C CB  . LEU B 2 438 ? 211.439 128.753 110.069 1.00 277.53 ? 460 LEU B CB  1 
ATOM   4881  C CG  . LEU B 2 438 ? 210.551 127.516 109.913 1.00 277.53 ? 460 LEU B CG  1 
ATOM   4882  C CD1 . LEU B 2 438 ? 210.298 127.214 108.444 1.00 277.53 ? 460 LEU B CD1 1 
ATOM   4883  C CD2 . LEU B 2 438 ? 211.171 126.315 110.612 1.00 277.53 ? 460 LEU B CD2 1 
ATOM   4884  N N   . SER B 2 439 ? 214.199 129.734 111.740 1.00 343.82 ? 461 SER B N   1 
ATOM   4885  C CA  . SER B 2 439 ? 215.328 130.651 111.756 1.00 343.82 ? 461 SER B CA  1 
ATOM   4886  C C   . SER B 2 439 ? 216.606 129.853 111.549 1.00 343.82 ? 461 SER B C   1 
ATOM   4887  O O   . SER B 2 439 ? 216.766 128.771 112.117 1.00 343.82 ? 461 SER B O   1 
ATOM   4888  C CB  . SER B 2 439 ? 215.395 131.435 113.072 1.00 343.82 ? 461 SER B CB  1 
ATOM   4889  O OG  . SER B 2 439 ? 215.181 130.585 114.184 1.00 343.82 ? 461 SER B OG  1 
ATOM   4890  N N   . ASP B 2 440 ? 217.508 130.396 110.734 1.00 389.57 ? 462 ASP B N   1 
ATOM   4891  C CA  . ASP B 2 440 ? 218.787 129.753 110.466 1.00 389.57 ? 462 ASP B CA  1 
ATOM   4892  C C   . ASP B 2 440 ? 219.793 129.935 111.596 1.00 389.57 ? 462 ASP B C   1 
ATOM   4893  O O   . ASP B 2 440 ? 220.937 129.487 111.461 1.00 389.57 ? 462 ASP B O   1 
ATOM   4894  C CB  . ASP B 2 440 ? 219.378 130.286 109.158 1.00 389.57 ? 462 ASP B CB  1 
ATOM   4895  C CG  . ASP B 2 440 ? 218.447 130.092 107.977 1.00 389.57 ? 462 ASP B CG  1 
ATOM   4896  O OD1 . ASP B 2 440 ? 217.567 129.210 108.051 1.00 389.57 ? 462 ASP B OD1 1 
ATOM   4897  O OD2 . ASP B 2 440 ? 218.596 130.822 106.974 1.00 389.57 ? 462 ASP B OD2 1 
ATOM   4898  N N   . LYS B 2 441 ? 219.402 130.576 112.697 1.00 397.42 ? 463 LYS B N   1 
ATOM   4899  C CA  . LYS B 2 441 ? 220.298 130.800 113.824 1.00 397.42 ? 463 LYS B CA  1 
ATOM   4900  C C   . LYS B 2 441 ? 219.753 130.325 115.162 1.00 397.42 ? 463 LYS B C   1 
ATOM   4901  O O   . LYS B 2 441 ? 220.553 130.059 116.067 1.00 397.42 ? 463 LYS B O   1 
ATOM   4902  C CB  . LYS B 2 441 ? 220.656 132.291 113.936 1.00 397.42 ? 463 LYS B CB  1 
ATOM   4903  C CG  . LYS B 2 441 ? 219.456 133.231 113.976 1.00 397.42 ? 463 LYS B CG  1 
ATOM   4904  C CD  . LYS B 2 441 ? 219.051 133.579 115.401 1.00 397.42 ? 463 LYS B CD  1 
ATOM   4905  C CE  . LYS B 2 441 ? 217.837 134.492 115.425 1.00 397.42 ? 463 LYS B CE  1 
ATOM   4906  N NZ  . LYS B 2 441 ? 217.474 134.894 116.812 1.00 397.42 ? 463 LYS B NZ  1 
ATOM   4907  N N   . ALA B 2 442 ? 218.435 130.206 115.325 1.00 368.14 ? 464 ALA B N   1 
ATOM   4908  C CA  . ALA B 2 442 ? 217.850 129.794 116.586 1.00 368.14 ? 464 ALA B CA  1 
ATOM   4909  C C   . ALA B 2 442 ? 216.958 128.574 116.390 1.00 368.14 ? 464 ALA B C   1 
ATOM   4910  O O   . ALA B 2 442 ? 216.221 128.497 115.401 1.00 368.14 ? 464 ALA B O   1 
ATOM   4911  C CB  . ALA B 2 442 ? 217.028 130.931 117.211 1.00 368.14 ? 464 ALA B CB  1 
ATOM   4912  N N   . PRO B 2 443 ? 217.000 127.607 117.311 1.00 338.87 ? 465 PRO B N   1 
ATOM   4913  C CA  . PRO B 2 443 ? 216.147 126.419 117.172 1.00 338.87 ? 465 PRO B CA  1 
ATOM   4914  C C   . PRO B 2 443 ? 214.689 126.713 117.488 1.00 338.87 ? 465 PRO B C   1 
ATOM   4915  O O   . PRO B 2 443 ? 214.323 127.862 117.758 1.00 338.87 ? 465 PRO B O   1 
ATOM   4916  C CB  . PRO B 2 443 ? 216.754 125.436 118.180 1.00 338.87 ? 465 PRO B CB  1 
ATOM   4917  C CG  . PRO B 2 443 ? 217.365 126.311 119.221 1.00 338.87 ? 465 PRO B CG  1 
ATOM   4918  C CD  . PRO B 2 443 ? 217.864 127.537 118.502 1.00 338.87 ? 465 PRO B CD  1 
ATOM   4919  N N   . CYS B 2 444 ? 213.850 125.681 117.457 1.00 285.63 ? 466 CYS B N   1 
ATOM   4920  C CA  . CYS B 2 444 ? 212.426 125.852 117.708 1.00 285.63 ? 466 CYS B CA  1 
ATOM   4921  C C   . CYS B 2 444 ? 212.131 125.839 119.202 1.00 285.63 ? 466 CYS B C   1 
ATOM   4922  O O   . CYS B 2 444 ? 212.666 125.010 119.946 1.00 285.63 ? 466 CYS B O   1 
ATOM   4923  C CB  . CYS B 2 444 ? 211.623 124.755 117.011 1.00 285.63 ? 466 CYS B CB  1 
ATOM   4924  S SG  . CYS B 2 444 ? 211.647 124.814 115.208 1.00 285.63 ? 466 CYS B SG  1 
ATOM   4925  N N   . ILE B 2 445 ? 211.276 126.759 119.635 1.00 278.57 ? 467 ILE B N   1 
ATOM   4926  C CA  . ILE B 2 445 ? 210.722 126.761 120.983 1.00 278.57 ? 467 ILE B CA  1 
ATOM   4927  C C   . ILE B 2 445 ? 209.366 126.065 120.897 1.00 278.57 ? 467 ILE B C   1 
ATOM   4928  O O   . ILE B 2 445 ? 208.345 126.681 120.575 1.00 278.57 ? 467 ILE B O   1 
ATOM   4929  C CB  . ILE B 2 445 ? 210.631 128.178 121.560 1.00 278.57 ? 467 ILE B CB  1 
ATOM   4930  C CG1 . ILE B 2 445 ? 210.005 129.149 120.552 1.00 278.57 ? 467 ILE B CG1 1 
ATOM   4931  C CG2 . ILE B 2 445 ? 212.007 128.663 121.999 1.00 278.57 ? 467 ILE B CG2 1 
ATOM   4932  C CD1 . ILE B 2 445 ? 209.999 130.592 121.012 1.00 278.57 ? 467 ILE B CD1 1 
ATOM   4933  N N   . THR B 2 446 ? 209.359 124.764 121.179 1.00 252.97 ? 468 THR B N   1 
ATOM   4934  C CA  . THR B 2 446 ? 208.185 123.930 120.943 1.00 252.97 ? 468 THR B CA  1 
ATOM   4935  C C   . THR B 2 446 ? 207.071 124.303 121.914 1.00 252.97 ? 468 THR B C   1 
ATOM   4936  O O   . THR B 2 446 ? 207.113 123.937 123.092 1.00 252.97 ? 468 THR B O   1 
ATOM   4937  C CB  . THR B 2 446 ? 208.554 122.456 121.081 1.00 252.97 ? 468 THR B CB  1 
ATOM   4938  O OG1 . THR B 2 446 ? 208.943 122.184 122.434 1.00 252.97 ? 468 THR B OG1 1 
ATOM   4939  C CG2 . THR B 2 446 ? 209.706 122.107 120.150 1.00 252.97 ? 468 THR B CG2 1 
ATOM   4940  N N   . ASP B 2 447 ? 206.074 125.030 121.418 1.00 247.80 ? 469 ASP B N   1 
ATOM   4941  C CA  . ASP B 2 447 ? 204.863 125.337 122.164 1.00 247.80 ? 469 ASP B CA  1 
ATOM   4942  C C   . ASP B 2 447 ? 203.717 124.506 121.604 1.00 247.80 ? 469 ASP B C   1 
ATOM   4943  O O   . ASP B 2 447 ? 203.590 124.352 120.385 1.00 247.80 ? 469 ASP B O   1 
ATOM   4944  C CB  . ASP B 2 447 ? 204.524 126.828 122.086 1.00 247.80 ? 469 ASP B CB  1 
ATOM   4945  C CG  . ASP B 2 447 ? 203.488 127.247 123.112 1.00 247.80 ? 469 ASP B CG  1 
ATOM   4946  O OD1 . ASP B 2 447 ? 203.151 126.425 123.990 1.00 247.80 ? 469 ASP B OD1 1 
ATOM   4947  O OD2 . ASP B 2 447 ? 203.011 128.399 123.042 1.00 247.80 ? 469 ASP B OD2 1 
ATOM   4948  N N   . TRP B 2 448 ? 202.885 123.969 122.493 1.00 242.84 ? 470 TRP B N   1 
ATOM   4949  C CA  . TRP B 2 448 ? 201.850 123.030 122.092 1.00 242.84 ? 470 TRP B CA  1 
ATOM   4950  C C   . TRP B 2 448 ? 200.543 123.358 122.799 1.00 242.84 ? 470 TRP B C   1 
ATOM   4951  O O   . TRP B 2 448 ? 200.515 124.055 123.816 1.00 242.84 ? 470 TRP B O   1 
ATOM   4952  C CB  . TRP B 2 448 ? 202.262 121.584 122.394 1.00 242.84 ? 470 TRP B CB  1 
ATOM   4953  C CG  . TRP B 2 448 ? 202.610 121.356 123.830 1.00 242.84 ? 470 TRP B CG  1 
ATOM   4954  C CD1 . TRP B 2 448 ? 203.818 121.573 124.425 1.00 242.84 ? 470 TRP B CD1 1 
ATOM   4955  C CD2 . TRP B 2 448 ? 201.739 120.869 124.857 1.00 242.84 ? 470 TRP B CD2 1 
ATOM   4956  N NE1 . TRP B 2 448 ? 203.753 121.250 125.758 1.00 242.84 ? 470 TRP B NE1 1 
ATOM   4957  C CE2 . TRP B 2 448 ? 202.488 120.814 126.048 1.00 242.84 ? 470 TRP B CE2 1 
ATOM   4958  C CE3 . TRP B 2 448 ? 200.398 120.472 124.883 1.00 242.84 ? 470 TRP B CE3 1 
ATOM   4959  C CZ2 . TRP B 2 448 ? 201.941 120.380 127.254 1.00 242.84 ? 470 TRP B CZ2 1 
ATOM   4960  C CZ3 . TRP B 2 448 ? 199.857 120.041 126.081 1.00 242.84 ? 470 TRP B CZ3 1 
ATOM   4961  C CH2 . TRP B 2 448 ? 200.628 119.998 127.250 1.00 242.84 ? 470 TRP B CH2 1 
ATOM   4962  N N   . GLN B 2 449 ? 199.453 122.838 122.237 1.00 299.61 ? 471 GLN B N   1 
ATOM   4963  C CA  . GLN B 2 449 ? 198.127 122.982 122.817 1.00 299.61 ? 471 GLN B CA  1 
ATOM   4964  C C   . GLN B 2 449 ? 197.293 121.773 122.421 1.00 299.61 ? 471 GLN B C   1 
ATOM   4965  O O   . GLN B 2 449 ? 197.440 121.231 121.322 1.00 299.61 ? 471 GLN B O   1 
ATOM   4966  C CB  . GLN B 2 449 ? 197.447 124.281 122.367 1.00 299.61 ? 471 GLN B CB  1 
ATOM   4967  C CG  . GLN B 2 449 ? 197.209 124.382 120.869 1.00 299.61 ? 471 GLN B CG  1 
ATOM   4968  C CD  . GLN B 2 449 ? 196.577 125.700 120.469 1.00 299.61 ? 471 GLN B CD  1 
ATOM   4969  O OE1 . GLN B 2 449 ? 196.654 126.686 121.202 1.00 299.61 ? 471 GLN B OE1 1 
ATOM   4970  N NE2 . GLN B 2 449 ? 195.944 125.724 119.302 1.00 299.61 ? 471 GLN B NE2 1 
ATOM   4971  N N   . GLN B 2 450 ? 196.418 121.351 123.330 1.00 291.33 ? 472 GLN B N   1 
ATOM   4972  C CA  . GLN B 2 450 ? 195.608 120.155 123.149 1.00 291.33 ? 472 GLN B CA  1 
ATOM   4973  C C   . GLN B 2 450 ? 194.136 120.536 123.091 1.00 291.33 ? 472 GLN B C   1 
ATOM   4974  O O   . GLN B 2 450 ? 193.659 121.317 123.922 1.00 291.33 ? 472 GLN B O   1 
ATOM   4975  C CB  . GLN B 2 450 ? 195.852 119.150 124.279 1.00 291.33 ? 472 GLN B CB  1 
ATOM   4976  C CG  . GLN B 2 450 ? 194.969 117.914 124.214 1.00 291.33 ? 472 GLN B CG  1 
ATOM   4977  C CD  . GLN B 2 450 ? 195.268 116.926 125.323 1.00 291.33 ? 472 GLN B CD  1 
ATOM   4978  O OE1 . GLN B 2 450 ? 196.303 117.011 125.984 1.00 291.33 ? 472 GLN B OE1 1 
ATOM   4979  N NE2 . GLN B 2 450 ? 194.360 115.980 125.534 1.00 291.33 ? 472 GLN B NE2 1 
ATOM   4980  N N   . GLU B 2 451 ? 193.424 119.986 122.111 1.00 268.74 ? 473 GLU B N   1 
ATOM   4981  C CA  . GLU B 2 451 ? 191.995 120.201 121.950 1.00 268.74 ? 473 GLU B CA  1 
ATOM   4982  C C   . GLU B 2 451 ? 191.311 118.861 121.711 1.00 268.74 ? 473 GLU B C   1 
ATOM   4983  O O   . GLU B 2 451 ? 191.958 117.846 121.439 1.00 268.74 ? 473 GLU B O   1 
ATOM   4984  C CB  . GLU B 2 451 ? 191.697 121.170 120.797 1.00 268.74 ? 473 GLU B CB  1 
ATOM   4985  C CG  . GLU B 2 451 ? 192.121 120.663 119.428 1.00 268.74 ? 473 GLU B CG  1 
ATOM   4986  C CD  . GLU B 2 451 ? 193.579 120.951 119.122 1.00 268.74 ? 473 GLU B CD  1 
ATOM   4987  O OE1 . GLU B 2 451 ? 194.258 121.564 119.972 1.00 268.74 ? 473 GLU B OE1 1 
ATOM   4988  O OE2 . GLU B 2 451 ? 194.044 120.565 118.030 1.00 268.74 ? 473 GLU B OE2 1 
ATOM   4989  N N   . ASP B 2 452 ? 189.985 118.868 121.814 1.00 242.52 ? 474 ASP B N   1 
ATOM   4990  C CA  . ASP B 2 452 ? 189.215 117.646 121.645 1.00 242.52 ? 474 ASP B CA  1 
ATOM   4991  C C   . ASP B 2 452 ? 189.250 117.178 120.192 1.00 242.52 ? 474 ASP B C   1 
ATOM   4992  O O   . ASP B 2 452 ? 189.613 117.921 119.276 1.00 242.52 ? 474 ASP B O   1 
ATOM   4993  C CB  . ASP B 2 452 ? 187.769 117.856 122.093 1.00 242.52 ? 474 ASP B CB  1 
ATOM   4994  C CG  . ASP B 2 452 ? 187.143 119.095 121.483 1.00 242.52 ? 474 ASP B CG  1 
ATOM   4995  O OD1 . ASP B 2 452 ? 187.872 119.873 120.831 1.00 242.52 ? 474 ASP B OD1 1 
ATOM   4996  O OD2 . ASP B 2 452 ? 185.921 119.291 121.653 1.00 242.52 ? 474 ASP B OD2 1 
ATOM   4997  N N   . GLY B 2 453 ? 188.863 115.921 119.991 1.00 229.53 ? 475 GLY B N   1 
ATOM   4998  C CA  . GLY B 2 453 ? 188.825 115.325 118.673 1.00 229.53 ? 475 GLY B CA  1 
ATOM   4999  C C   . GLY B 2 453 ? 187.581 115.606 117.865 1.00 229.53 ? 475 GLY B C   1 
ATOM   5000  O O   . GLY B 2 453 ? 187.491 115.170 116.714 1.00 229.53 ? 475 GLY B O   1 
ATOM   5001  N N   . THR B 2 454 ? 186.611 116.323 118.432 1.00 221.19 ? 476 THR B N   1 
ATOM   5002  C CA  . THR B 2 454 ? 185.376 116.635 117.727 1.00 221.19 ? 476 THR B CA  1 
ATOM   5003  C C   . THR B 2 454 ? 185.481 117.879 116.856 1.00 221.19 ? 476 THR B C   1 
ATOM   5004  O O   . THR B 2 454 ? 184.707 118.016 115.902 1.00 221.19 ? 476 THR B O   1 
ATOM   5005  C CB  . THR B 2 454 ? 184.227 116.818 118.723 1.00 221.19 ? 476 THR B CB  1 
ATOM   5006  O OG1 . THR B 2 454 ? 184.302 118.125 119.307 1.00 221.19 ? 476 THR B OG1 1 
ATOM   5007  C CG2 . THR B 2 454 ? 184.306 115.772 119.825 1.00 221.19 ? 476 THR B CG2 1 
ATOM   5008  N N   . VAL B 2 455 ? 186.411 118.782 117.158 1.00 219.62 ? 477 VAL B N   1 
ATOM   5009  C CA  . VAL B 2 455 ? 186.597 120.012 116.398 1.00 219.62 ? 477 VAL B CA  1 
ATOM   5010  C C   . VAL B 2 455 ? 187.759 119.818 115.437 1.00 219.62 ? 477 VAL B C   1 
ATOM   5011  O O   . VAL B 2 455 ? 188.822 119.317 115.827 1.00 219.62 ? 477 VAL B O   1 
ATOM   5012  C CB  . VAL B 2 455 ? 186.845 121.211 117.330 1.00 219.62 ? 477 VAL B CB  1 
ATOM   5013  C CG1 . VAL B 2 455 ? 186.763 122.514 116.550 1.00 219.62 ? 477 VAL B CG1 1 
ATOM   5014  C CG2 . VAL B 2 455 ? 185.847 121.205 118.477 1.00 219.62 ? 477 VAL B CG2 1 
ATOM   5015  N N   . HIS B 2 456 ? 187.561 120.213 114.179 1.00 207.97 ? 478 HIS B N   1 
ATOM   5016  C CA  . HIS B 2 456 ? 188.574 120.067 113.142 1.00 207.97 ? 478 HIS B CA  1 
ATOM   5017  C C   . HIS B 2 456 ? 189.207 121.396 112.748 1.00 207.97 ? 478 HIS B C   1 
ATOM   5018  O O   . HIS B 2 456 ? 189.953 121.448 111.764 1.00 207.97 ? 478 HIS B O   1 
ATOM   5019  C CB  . HIS B 2 456 ? 187.973 119.387 111.910 1.00 207.97 ? 478 HIS B CB  1 
ATOM   5020  C CG  . HIS B 2 456 ? 186.737 120.056 111.392 1.00 207.97 ? 478 HIS B CG  1 
ATOM   5021  N ND1 . HIS B 2 456 ? 186.762 121.278 110.756 1.00 207.97 ? 478 HIS B ND1 1 
ATOM   5022  C CD2 . HIS B 2 456 ? 185.439 119.671 111.416 1.00 207.97 ? 478 HIS B CD2 1 
ATOM   5023  C CE1 . HIS B 2 456 ? 185.533 121.618 110.411 1.00 207.97 ? 478 HIS B CE1 1 
ATOM   5024  N NE2 . HIS B 2 456 ? 184.711 120.660 110.800 1.00 207.97 ? 478 HIS B NE2 1 
ATOM   5025  N N   . ARG B 2 457 ? 188.932 122.468 113.487 1.00 226.44 ? 479 ARG B N   1 
ATOM   5026  C CA  . ARG B 2 457 ? 189.490 123.780 113.175 1.00 226.44 ? 479 ARG B CA  1 
ATOM   5027  C C   . ARG B 2 457 ? 189.638 124.567 114.466 1.00 226.44 ? 479 ARG B C   1 
ATOM   5028  O O   . ARG B 2 457 ? 188.638 124.903 115.107 1.00 226.44 ? 479 ARG B O   1 
ATOM   5029  C CB  . ARG B 2 457 ? 188.605 124.533 112.179 1.00 226.44 ? 479 ARG B CB  1 
ATOM   5030  C CG  . ARG B 2 457 ? 187.117 124.265 112.341 1.00 226.44 ? 479 ARG B CG  1 
ATOM   5031  C CD  . ARG B 2 457 ? 186.297 125.108 111.379 1.00 226.44 ? 479 ARG B CD  1 
ATOM   5032  N NE  . ARG B 2 457 ? 186.402 126.533 111.679 1.00 226.44 ? 479 ARG B NE  1 
ATOM   5033  C CZ  . ARG B 2 457 ? 185.774 127.488 111.000 1.00 226.44 ? 479 ARG B CZ  1 
ATOM   5034  N NH1 . ARG B 2 457 ? 184.992 127.172 109.976 1.00 226.44 ? 479 ARG B NH1 1 
ATOM   5035  N NH2 . ARG B 2 457 ? 185.928 128.759 111.344 1.00 226.44 ? 479 ARG B NH2 1 
ATOM   5036  N N   . THR B 2 458 ? 190.882 124.858 114.846 1.00 282.83 ? 480 THR B N   1 
ATOM   5037  C CA  . THR B 2 458 ? 191.179 125.605 116.059 1.00 282.83 ? 480 THR B CA  1 
ATOM   5038  C C   . THR B 2 458 ? 192.201 126.686 115.732 1.00 282.83 ? 480 THR B C   1 
ATOM   5039  O O   . THR B 2 458 ? 192.688 126.792 114.602 1.00 282.83 ? 480 THR B O   1 
ATOM   5040  C CB  . THR B 2 458 ? 191.697 124.687 117.175 1.00 282.83 ? 480 THR B CB  1 
ATOM   5041  O OG1 . THR B 2 458 ? 192.899 124.036 116.744 1.00 282.83 ? 480 THR B OG1 1 
ATOM   5042  C CG2 . THR B 2 458 ? 190.656 123.638 117.545 1.00 282.83 ? 480 THR B CG2 1 
ATOM   5043  N N   . TYR B 2 459 ? 192.526 127.497 116.736 1.00 331.60 ? 481 TYR B N   1 
ATOM   5044  C CA  . TYR B 2 459 ? 193.507 128.562 116.605 1.00 331.60 ? 481 TYR B CA  1 
ATOM   5045  C C   . TYR B 2 459 ? 194.601 128.387 117.650 1.00 331.60 ? 481 TYR B C   1 
ATOM   5046  O O   . TYR B 2 459 ? 194.386 127.779 118.703 1.00 331.60 ? 481 TYR B O   1 
ATOM   5047  C CB  . TYR B 2 459 ? 192.858 129.947 116.753 1.00 331.60 ? 481 TYR B CB  1 
ATOM   5048  C CG  . TYR B 2 459 ? 192.286 130.225 118.126 1.00 331.60 ? 481 TYR B CG  1 
ATOM   5049  C CD1 . TYR B 2 459 ? 192.922 131.097 119.000 1.00 331.60 ? 481 TYR B CD1 1 
ATOM   5050  C CD2 . TYR B 2 459 ? 191.105 129.625 118.544 1.00 331.60 ? 481 TYR B CD2 1 
ATOM   5051  C CE1 . TYR B 2 459 ? 192.402 131.356 120.255 1.00 331.60 ? 481 TYR B CE1 1 
ATOM   5052  C CE2 . TYR B 2 459 ? 190.578 129.878 119.796 1.00 331.60 ? 481 TYR B CE2 1 
ATOM   5053  C CZ  . TYR B 2 459 ? 191.230 130.745 120.647 1.00 331.60 ? 481 TYR B CZ  1 
ATOM   5054  O OH  . TYR B 2 459 ? 190.708 131.000 121.894 1.00 331.60 ? 481 TYR B OH  1 
ATOM   5055  N N   . LEU B 2 460 ? 195.779 128.927 117.347 1.00 332.78 ? 482 LEU B N   1 
ATOM   5056  C CA  . LEU B 2 460 ? 196.938 128.802 118.225 1.00 332.78 ? 482 LEU B CA  1 
ATOM   5057  C C   . LEU B 2 460 ? 196.795 129.779 119.386 1.00 332.78 ? 482 LEU B C   1 
ATOM   5058  O O   . LEU B 2 460 ? 196.899 130.996 119.201 1.00 332.78 ? 482 LEU B O   1 
ATOM   5059  C CB  . LEU B 2 460 ? 198.227 129.053 117.449 1.00 332.78 ? 482 LEU B CB  1 
ATOM   5060  C CG  . LEU B 2 460 ? 198.409 128.291 116.133 1.00 332.78 ? 482 LEU B CG  1 
ATOM   5061  C CD1 . LEU B 2 460 ? 197.940 129.118 114.946 1.00 332.78 ? 482 LEU B CD1 1 
ATOM   5062  C CD2 . LEU B 2 460 ? 199.858 127.871 115.952 1.00 332.78 ? 482 LEU B CD2 1 
ATOM   5063  N N   . ARG B 2 461 ? 196.558 129.250 120.584 1.00 367.88 ? 483 ARG B N   1 
ATOM   5064  C CA  . ARG B 2 461 ? 196.426 130.069 121.788 1.00 367.88 ? 483 ARG B CA  1 
ATOM   5065  C C   . ARG B 2 461 ? 197.823 130.420 122.284 1.00 367.88 ? 483 ARG B C   1 
ATOM   5066  O O   . ARG B 2 461 ? 198.432 129.693 123.070 1.00 367.88 ? 483 ARG B O   1 
ATOM   5067  C CB  . ARG B 2 461 ? 195.622 129.335 122.854 1.00 367.88 ? 483 ARG B CB  1 
ATOM   5068  C CG  . ARG B 2 461 ? 194.164 129.108 122.488 1.00 367.88 ? 483 ARG B CG  1 
ATOM   5069  C CD  . ARG B 2 461 ? 193.533 128.039 123.366 1.00 367.88 ? 483 ARG B CD  1 
ATOM   5070  N NE  . ARG B 2 461 ? 194.080 126.713 123.096 1.00 367.88 ? 483 ARG B NE  1 
ATOM   5071  C CZ  . ARG B 2 461 ? 193.648 125.595 123.672 1.00 367.88 ? 483 ARG B CZ  1 
ATOM   5072  N NH1 . ARG B 2 461 ? 192.659 125.641 124.555 1.00 367.88 ? 483 ARG B NH1 1 
ATOM   5073  N NH2 . ARG B 2 461 ? 194.203 124.431 123.366 1.00 367.88 ? 483 ARG B NH2 1 
ATOM   5074  N N   . GLY B 2 462 ? 198.338 131.551 121.815 1.00 361.82 ? 484 GLY B N   1 
ATOM   5075  C CA  . GLY B 2 462 ? 199.662 131.986 122.219 1.00 361.82 ? 484 GLY B CA  1 
ATOM   5076  C C   . GLY B 2 462 ? 199.949 133.375 121.695 1.00 361.82 ? 484 GLY B C   1 
ATOM   5077  O O   . GLY B 2 462 ? 199.180 133.943 120.915 1.00 361.82 ? 484 GLY B O   1 
ATOM   5078  N N   . ASN B 2 463 ? 201.081 133.918 122.140 1.00 341.00 ? 485 ASN B N   1 
ATOM   5079  C CA  . ASN B 2 463 ? 201.522 135.252 121.734 1.00 341.00 ? 485 ASN B CA  1 
ATOM   5080  C C   . ASN B 2 463 ? 202.353 135.111 120.466 1.00 341.00 ? 485 ASN B C   1 
ATOM   5081  O O   . ASN B 2 463 ? 203.576 134.970 120.509 1.00 341.00 ? 485 ASN B O   1 
ATOM   5082  C CB  . ASN B 2 463 ? 202.307 135.925 122.852 1.00 341.00 ? 485 ASN B CB  1 
ATOM   5083  C CG  . ASN B 2 463 ? 202.503 137.410 122.615 1.00 341.00 ? 485 ASN B CG  1 
ATOM   5084  O OD1 . ASN B 2 463 ? 203.552 137.968 122.934 1.00 341.00 ? 485 ASN B OD1 1 
ATOM   5085  N ND2 . ASN B 2 463 ? 201.489 138.058 122.053 1.00 341.00 ? 485 ASN B ND2 1 
ATOM   5086  N N   . LEU B 2 464 ? 201.680 135.151 119.321 1.00 285.10 ? 486 LEU B N   1 
ATOM   5087  C CA  . LEU B 2 464 ? 202.360 135.024 118.041 1.00 285.10 ? 486 LEU B CA  1 
ATOM   5088  C C   . LEU B 2 464 ? 202.963 136.358 117.619 1.00 285.10 ? 486 LEU B C   1 
ATOM   5089  O O   . LEU B 2 464 ? 202.408 137.428 117.883 1.00 285.10 ? 486 LEU B O   1 
ATOM   5090  C CB  . LEU B 2 464 ? 201.398 134.525 116.960 1.00 285.10 ? 486 LEU B CB  1 
ATOM   5091  C CG  . LEU B 2 464 ? 201.117 133.022 116.863 1.00 285.10 ? 486 LEU B CG  1 
ATOM   5092  C CD1 . LEU B 2 464 ? 200.402 132.489 118.099 1.00 285.10 ? 486 LEU B CD1 1 
ATOM   5093  C CD2 . LEU B 2 464 ? 200.320 132.713 115.604 1.00 285.10 ? 486 LEU B CD2 1 
ATOM   5094  N N   . ALA B 2 465 ? 204.113 136.282 116.957 1.00 247.62 ? 487 ALA B N   1 
ATOM   5095  C CA  . ALA B 2 465 ? 204.823 137.454 116.469 1.00 247.62 ? 487 ALA B CA  1 
ATOM   5096  C C   . ALA B 2 465 ? 204.640 137.579 114.963 1.00 247.62 ? 487 ALA B C   1 
ATOM   5097  O O   . ALA B 2 465 ? 204.644 136.577 114.241 1.00 247.62 ? 487 ALA B O   1 
ATOM   5098  C CB  . ALA B 2 465 ? 206.313 137.377 116.810 1.00 247.62 ? 487 ALA B CB  1 
ATOM   5099  N N   . GLU B 2 466 ? 204.477 138.814 114.496 1.00 245.05 ? 488 GLU B N   1 
ATOM   5100  C CA  . GLU B 2 466 ? 204.278 139.069 113.080 1.00 245.05 ? 488 GLU B CA  1 
ATOM   5101  C C   . GLU B 2 466 ? 205.602 138.963 112.325 1.00 245.05 ? 488 GLU B C   1 
ATOM   5102  O O   . GLU B 2 466 ? 206.688 138.959 112.912 1.00 245.05 ? 488 GLU B O   1 
ATOM   5103  C CB  . GLU B 2 466 ? 203.649 140.445 112.870 1.00 245.05 ? 488 GLU B CB  1 
ATOM   5104  C CG  . GLU B 2 466 ? 202.645 140.834 113.944 1.00 245.05 ? 488 GLU B CG  1 
ATOM   5105  C CD  . GLU B 2 466 ? 201.875 142.092 113.596 1.00 245.05 ? 488 GLU B CD  1 
ATOM   5106  O OE1 . GLU B 2 466 ? 200.913 142.001 112.805 1.00 245.05 ? 488 GLU B OE1 1 
ATOM   5107  O OE2 . GLU B 2 466 ? 202.233 143.171 114.112 1.00 245.05 ? 488 GLU B OE2 1 
ATOM   5108  N N   . SER B 2 467 ? 205.494 138.871 110.998 1.00 249.81 ? 489 SER B N   1 
ATOM   5109  C CA  . SER B 2 467 ? 206.650 138.761 110.105 1.00 249.81 ? 489 SER B CA  1 
ATOM   5110  C C   . SER B 2 467 ? 207.524 137.559 110.451 1.00 249.81 ? 489 SER B C   1 
ATOM   5111  O O   . SER B 2 467 ? 208.747 137.602 110.298 1.00 249.81 ? 489 SER B O   1 
ATOM   5112  C CB  . SER B 2 467 ? 207.483 140.047 110.112 1.00 249.81 ? 489 SER B CB  1 
ATOM   5113  O OG  . SER B 2 467 ? 208.789 139.811 109.616 1.00 249.81 ? 489 SER B OG  1 
ATOM   5114  N N   . LYS B 2 468 ? 206.904 136.478 110.919 1.00 233.51 ? 490 LYS B N   1 
ATOM   5115  C CA  . LYS B 2 468 ? 207.613 135.266 111.301 1.00 233.51 ? 490 LYS B CA  1 
ATOM   5116  C C   . LYS B 2 468 ? 206.915 134.056 110.700 1.00 233.51 ? 490 LYS B C   1 
ATOM   5117  O O   . LYS B 2 468 ? 205.682 133.987 110.678 1.00 233.51 ? 490 LYS B O   1 
ATOM   5118  C CB  . LYS B 2 468 ? 207.691 135.122 112.826 1.00 233.51 ? 490 LYS B CB  1 
ATOM   5119  C CG  . LYS B 2 468 ? 208.537 136.184 113.509 1.00 233.51 ? 490 LYS B CG  1 
ATOM   5120  C CD  . LYS B 2 468 ? 209.981 136.125 113.037 1.00 233.51 ? 490 LYS B CD  1 
ATOM   5121  C CE  . LYS B 2 468 ? 210.825 137.196 113.709 1.00 233.51 ? 490 LYS B CE  1 
ATOM   5122  N NZ  . LYS B 2 468 ? 212.243 137.151 113.256 1.00 233.51 ? 490 LYS B NZ  1 
ATOM   5123  N N   . CYS B 2 469 ? 207.708 133.106 110.213 1.00 224.39 ? 491 CYS B N   1 
ATOM   5124  C CA  . CYS B 2 469 ? 207.181 131.889 109.610 1.00 224.39 ? 491 CYS B CA  1 
ATOM   5125  C C   . CYS B 2 469 ? 206.997 130.831 110.691 1.00 224.39 ? 491 CYS B C   1 
ATOM   5126  O O   . CYS B 2 469 ? 207.960 130.454 111.368 1.00 224.39 ? 491 CYS B O   1 
ATOM   5127  C CB  . CYS B 2 469 ? 208.114 131.380 108.512 1.00 224.39 ? 491 CYS B CB  1 
ATOM   5128  S SG  . CYS B 2 469 ? 207.747 129.704 107.944 1.00 224.39 ? 491 CYS B SG  1 
ATOM   5129  N N   . TYR B 2 470 ? 205.766 130.355 110.849 1.00 218.91 ? 492 TYR B N   1 
ATOM   5130  C CA  . TYR B 2 470 ? 205.427 129.346 111.843 1.00 218.91 ? 492 TYR B CA  1 
ATOM   5131  C C   . TYR B 2 470 ? 205.222 128.005 111.152 1.00 218.91 ? 492 TYR B C   1 
ATOM   5132  O O   . TYR B 2 470 ? 204.442 127.906 110.199 1.00 218.91 ? 492 TYR B O   1 
ATOM   5133  C CB  . TYR B 2 470 ? 204.170 129.741 112.619 1.00 218.91 ? 492 TYR B CB  1 
ATOM   5134  C CG  . TYR B 2 470 ? 204.374 130.911 113.555 1.00 218.91 ? 492 TYR B CG  1 
ATOM   5135  C CD1 . TYR B 2 470 ? 204.732 130.710 114.881 1.00 218.91 ? 492 TYR B CD1 1 
ATOM   5136  C CD2 . TYR B 2 470 ? 204.210 132.217 113.110 1.00 218.91 ? 492 TYR B CD2 1 
ATOM   5137  C CE1 . TYR B 2 470 ? 204.921 131.777 115.739 1.00 218.91 ? 492 TYR B CE1 1 
ATOM   5138  C CE2 . TYR B 2 470 ? 204.397 133.290 113.961 1.00 218.91 ? 492 TYR B CE2 1 
ATOM   5139  C CZ  . TYR B 2 470 ? 204.752 133.064 115.274 1.00 218.91 ? 492 TYR B CZ  1 
ATOM   5140  O OH  . TYR B 2 470 ? 204.939 134.128 116.126 1.00 218.91 ? 492 TYR B OH  1 
ATOM   5141  N N   . LEU B 2 471 ? 205.924 126.981 111.631 1.00 181.97 ? 493 LEU B N   1 
ATOM   5142  C CA  . LEU B 2 471 ? 205.823 125.628 111.085 1.00 181.97 ? 493 LEU B CA  1 
ATOM   5143  C C   . LEU B 2 471 ? 204.858 124.842 111.966 1.00 181.97 ? 493 LEU B C   1 
ATOM   5144  O O   . LEU B 2 471 ? 205.250 124.234 112.963 1.00 181.97 ? 493 LEU B O   1 
ATOM   5145  C CB  . LEU B 2 471 ? 207.195 124.968 111.013 1.00 181.97 ? 493 LEU B CB  1 
ATOM   5146  C CG  . LEU B 2 471 ? 207.248 123.579 110.374 1.00 181.97 ? 493 LEU B CG  1 
ATOM   5147  C CD1 . LEU B 2 471 ? 206.732 123.630 108.944 1.00 181.97 ? 493 LEU B CD1 1 
ATOM   5148  C CD2 . LEU B 2 471 ? 208.662 123.021 110.418 1.00 181.97 ? 493 LEU B CD2 1 
ATOM   5149  N N   . ILE B 2 472 ? 203.584 124.854 111.589 1.00 176.57 ? 494 ILE B N   1 
ATOM   5150  C CA  . ILE B 2 472 ? 202.550 124.175 112.362 1.00 176.57 ? 494 ILE B CA  1 
ATOM   5151  C C   . ILE B 2 472 ? 202.602 122.683 112.062 1.00 176.57 ? 494 ILE B C   1 
ATOM   5152  O O   . ILE B 2 472 ? 202.611 122.270 110.897 1.00 176.57 ? 494 ILE B O   1 
ATOM   5153  C CB  . ILE B 2 472 ? 201.160 124.754 112.050 1.00 176.57 ? 494 ILE B CB  1 
ATOM   5154  C CG1 . ILE B 2 472 ? 201.152 126.277 112.214 1.00 176.57 ? 494 ILE B CG1 1 
ATOM   5155  C CG2 . ILE B 2 472 ? 200.105 124.117 112.942 1.00 176.57 ? 494 ILE B CG2 1 
ATOM   5156  C CD1 . ILE B 2 472 ? 201.325 127.043 110.915 1.00 176.57 ? 494 ILE B CD1 1 
ATOM   5157  N N   . THR B 2 473 ? 202.635 121.871 113.116 1.00 174.30 ? 495 THR B N   1 
ATOM   5158  C CA  . THR B 2 473 ? 202.657 120.418 113.000 1.00 174.30 ? 495 THR B CA  1 
ATOM   5159  C C   . THR B 2 473 ? 201.475 119.849 113.771 1.00 174.30 ? 495 THR B C   1 
ATOM   5160  O O   . THR B 2 473 ? 201.349 120.081 114.978 1.00 174.30 ? 495 THR B O   1 
ATOM   5161  C CB  . THR B 2 473 ? 203.971 119.839 113.527 1.00 174.30 ? 495 THR B CB  1 
ATOM   5162  O OG1 . THR B 2 473 ? 205.068 120.378 112.777 1.00 174.30 ? 495 THR B OG1 1 
ATOM   5163  C CG2 . THR B 2 473 ? 203.973 118.323 113.399 1.00 174.30 ? 495 THR B CG2 1 
ATOM   5164  N N   . VAL B 2 474 ? 200.616 119.108 113.076 1.00 172.98 ? 496 VAL B N   1 
ATOM   5165  C CA  . VAL B 2 474 ? 199.429 118.501 113.666 1.00 172.98 ? 496 VAL B CA  1 
ATOM   5166  C C   . VAL B 2 474 ? 199.605 116.989 113.674 1.00 172.98 ? 496 VAL B C   1 
ATOM   5167  O O   . VAL B 2 474 ? 200.156 116.410 112.729 1.00 172.98 ? 496 VAL B O   1 
ATOM   5168  C CB  . VAL B 2 474 ? 198.148 118.915 112.912 1.00 172.98 ? 496 VAL B CB  1 
ATOM   5169  C CG1 . VAL B 2 474 ? 198.182 118.426 111.470 1.00 172.98 ? 496 VAL B CG1 1 
ATOM   5170  C CG2 . VAL B 2 474 ? 196.909 118.393 113.628 1.00 172.98 ? 496 VAL B CG2 1 
ATOM   5171  N N   . THR B 2 475 ? 199.158 116.353 114.754 1.00 192.29 ? 497 THR B N   1 
ATOM   5172  C CA  . THR B 2 475 ? 199.266 114.907 114.887 1.00 192.29 ? 497 THR B CA  1 
ATOM   5173  C C   . THR B 2 475 ? 198.003 114.341 115.523 1.00 192.29 ? 497 THR B C   1 
ATOM   5174  O O   . THR B 2 475 ? 197.667 114.695 116.660 1.00 192.29 ? 497 THR B O   1 
ATOM   5175  C CB  . THR B 2 475 ? 200.493 114.530 115.720 1.00 192.29 ? 497 THR B CB  1 
ATOM   5176  O OG1 . THR B 2 475 ? 201.673 115.056 115.101 1.00 192.29 ? 497 THR B OG1 1 
ATOM   5177  C CG2 . THR B 2 475 ? 200.615 113.020 115.831 1.00 192.29 ? 497 THR B CG2 1 
ATOM   5178  N N   . PRO B 2 476 ? 197.278 113.467 114.827 1.00 216.79 ? 498 PRO B N   1 
ATOM   5179  C CA  . PRO B 2 476 ? 196.072 112.879 115.420 1.00 216.79 ? 498 PRO B CA  1 
ATOM   5180  C C   . PRO B 2 476 ? 196.424 111.861 116.492 1.00 216.79 ? 498 PRO B C   1 
ATOM   5181  O O   . PRO B 2 476 ? 197.389 111.103 116.364 1.00 216.79 ? 498 PRO B O   1 
ATOM   5182  C CB  . PRO B 2 476 ? 195.375 112.219 114.225 1.00 216.79 ? 498 PRO B CB  1 
ATOM   5183  C CG  . PRO B 2 476 ? 196.486 111.905 113.279 1.00 216.79 ? 498 PRO B CG  1 
ATOM   5184  C CD  . PRO B 2 476 ? 197.509 112.998 113.450 1.00 216.79 ? 498 PRO B CD  1 
ATOM   5185  N N   . VAL B 2 477 ? 195.628 111.849 117.558 1.00 241.81 ? 499 VAL B N   1 
ATOM   5186  C CA  . VAL B 2 477 ? 195.835 110.959 118.696 1.00 241.81 ? 499 VAL B CA  1 
ATOM   5187  C C   . VAL B 2 477 ? 194.754 109.889 118.664 1.00 241.81 ? 499 VAL B C   1 
ATOM   5188  O O   . VAL B 2 477 ? 193.562 110.194 118.794 1.00 241.81 ? 499 VAL B O   1 
ATOM   5189  C CB  . VAL B 2 477 ? 195.813 111.725 120.027 1.00 241.81 ? 499 VAL B CB  1 
ATOM   5190  C CG1 . VAL B 2 477 ? 195.903 110.757 121.196 1.00 241.81 ? 499 VAL B CG1 1 
ATOM   5191  C CG2 . VAL B 2 477 ? 196.949 112.736 120.075 1.00 241.81 ? 499 VAL B CG2 1 
ATOM   5192  N N   . TYR B 2 478 ? 195.169 108.639 118.490 1.00 239.98 ? 500 TYR B N   1 
ATOM   5193  C CA  . TYR B 2 478 ? 194.265 107.503 118.466 1.00 239.98 ? 500 TYR B CA  1 
ATOM   5194  C C   . TYR B 2 478 ? 194.338 106.758 119.798 1.00 239.98 ? 500 TYR B C   1 
ATOM   5195  O O   . TYR B 2 478 ? 194.999 107.192 120.746 1.00 239.98 ? 500 TYR B O   1 
ATOM   5196  C CB  . TYR B 2 478 ? 194.600 106.593 117.283 1.00 239.98 ? 500 TYR B CB  1 
ATOM   5197  C CG  . TYR B 2 478 ? 194.594 107.300 115.948 1.00 239.98 ? 500 TYR B CG  1 
ATOM   5198  C CD1 . TYR B 2 478 ? 193.407 107.514 115.259 1.00 239.98 ? 500 TYR B CD1 1 
ATOM   5199  C CD2 . TYR B 2 478 ? 195.775 107.753 115.375 1.00 239.98 ? 500 TYR B CD2 1 
ATOM   5200  C CE1 . TYR B 2 478 ? 193.396 108.160 114.038 1.00 239.98 ? 500 TYR B CE1 1 
ATOM   5201  C CE2 . TYR B 2 478 ? 195.774 108.400 114.153 1.00 239.98 ? 500 TYR B CE2 1 
ATOM   5202  C CZ  . TYR B 2 478 ? 194.582 108.601 113.490 1.00 239.98 ? 500 TYR B CZ  1 
ATOM   5203  O OH  . TYR B 2 478 ? 194.576 109.245 112.274 1.00 239.98 ? 500 TYR B OH  1 
ATOM   5204  N N   . ALA B 2 479 ? 193.649 105.618 119.875 1.00 232.03 ? 501 ALA B N   1 
ATOM   5205  C CA  . ALA B 2 479 ? 193.654 104.816 121.091 1.00 232.03 ? 501 ALA B CA  1 
ATOM   5206  C C   . ALA B 2 479 ? 194.948 104.035 121.277 1.00 232.03 ? 501 ALA B C   1 
ATOM   5207  O O   . ALA B 2 479 ? 195.302 103.713 122.417 1.00 232.03 ? 501 ALA B O   1 
ATOM   5208  C CB  . ALA B 2 479 ? 192.468 103.850 121.090 1.00 232.03 ? 501 ALA B CB  1 
ATOM   5209  N N   . ASP B 2 480 ? 195.659 103.726 120.194 1.00 219.56 ? 502 ASP B N   1 
ATOM   5210  C CA  . ASP B 2 480 ? 196.910 102.982 120.265 1.00 219.56 ? 502 ASP B CA  1 
ATOM   5211  C C   . ASP B 2 480 ? 198.138 103.881 120.259 1.00 219.56 ? 502 ASP B C   1 
ATOM   5212  O O   . ASP B 2 480 ? 199.094 103.619 120.994 1.00 219.56 ? 502 ASP B O   1 
ATOM   5213  C CB  . ASP B 2 480 ? 197.003 101.990 119.101 1.00 219.56 ? 502 ASP B CB  1 
ATOM   5214  C CG  . ASP B 2 480 ? 195.935 100.916 119.164 1.00 219.56 ? 502 ASP B CG  1 
ATOM   5215  O OD1 . ASP B 2 480 ? 194.747 101.245 118.970 1.00 219.56 ? 502 ASP B OD1 1 
ATOM   5216  O OD2 . ASP B 2 480 ? 196.285 99.742  119.407 1.00 219.56 ? 502 ASP B OD2 1 
ATOM   5217  N N   . GLY B 2 481 ? 198.136 104.934 119.446 1.00 214.81 ? 503 GLY B N   1 
ATOM   5218  C CA  . GLY B 2 481 ? 199.253 105.842 119.376 1.00 214.81 ? 503 GLY B CA  1 
ATOM   5219  C C   . GLY B 2 481 ? 198.976 107.029 118.477 1.00 214.81 ? 503 GLY B C   1 
ATOM   5220  O O   . GLY B 2 481 ? 197.922 107.125 117.840 1.00 214.81 ? 503 GLY B O   1 
ATOM   5221  N N   . PRO B 2 482 ? 199.923 107.961 118.410 1.00 212.44 ? 504 PRO B N   1 
ATOM   5222  C CA  . PRO B 2 482 ? 199.732 109.142 117.563 1.00 212.44 ? 504 PRO B CA  1 
ATOM   5223  C C   . PRO B 2 482 ? 199.867 108.802 116.088 1.00 212.44 ? 504 PRO B C   1 
ATOM   5224  O O   . PRO B 2 482 ? 200.517 107.826 115.704 1.00 212.44 ? 504 PRO B O   1 
ATOM   5225  C CB  . PRO B 2 482 ? 200.848 110.088 118.020 1.00 212.44 ? 504 PRO B CB  1 
ATOM   5226  C CG  . PRO B 2 482 ? 201.915 109.177 118.524 1.00 212.44 ? 504 PRO B CG  1 
ATOM   5227  C CD  . PRO B 2 482 ? 201.207 107.995 119.132 1.00 212.44 ? 504 PRO B CD  1 
ATOM   5228  N N   . GLY B 2 483 ? 199.237 109.626 115.257 1.00 204.00 ? 505 GLY B N   1 
ATOM   5229  C CA  . GLY B 2 483 ? 199.285 109.452 113.822 1.00 204.00 ? 505 GLY B CA  1 
ATOM   5230  C C   . GLY B 2 483 ? 200.531 110.065 113.209 1.00 204.00 ? 505 GLY B C   1 
ATOM   5231  O O   . GLY B 2 483 ? 201.452 110.515 113.893 1.00 204.00 ? 505 GLY B O   1 
ATOM   5232  N N   . SER B 2 484 ? 200.550 110.074 111.883 1.00 184.15 ? 506 SER B N   1 
ATOM   5233  C CA  . SER B 2 484 ? 201.676 110.645 111.153 1.00 184.15 ? 506 SER B CA  1 
ATOM   5234  C C   . SER B 2 484 ? 201.610 112.167 111.206 1.00 184.15 ? 506 SER B C   1 
ATOM   5235  O O   . SER B 2 484 ? 200.583 112.750 110.843 1.00 184.15 ? 506 SER B O   1 
ATOM   5236  C CB  . SER B 2 484 ? 201.675 110.169 109.704 1.00 184.15 ? 506 SER B CB  1 
ATOM   5237  O OG  . SER B 2 484 ? 202.053 108.806 109.615 1.00 184.15 ? 506 SER B OG  1 
ATOM   5238  N N   . PRO B 2 485 ? 202.671 112.840 111.647 1.00 153.29 ? 507 PRO B N   1 
ATOM   5239  C CA  . PRO B 2 485 ? 202.631 114.304 111.736 1.00 153.29 ? 507 PRO B CA  1 
ATOM   5240  C C   . PRO B 2 485 ? 202.775 114.958 110.371 1.00 153.29 ? 507 PRO B C   1 
ATOM   5241  O O   . PRO B 2 485 ? 203.528 114.495 109.510 1.00 153.29 ? 507 PRO B O   1 
ATOM   5242  C CB  . PRO B 2 485 ? 203.827 114.632 112.637 1.00 153.29 ? 507 PRO B CB  1 
ATOM   5243  C CG  . PRO B 2 485 ? 204.784 113.514 112.393 1.00 153.29 ? 507 PRO B CG  1 
ATOM   5244  C CD  . PRO B 2 485 ? 203.948 112.287 112.130 1.00 153.29 ? 507 PRO B CD  1 
ATOM   5245  N N   . GLU B 2 486 ? 202.038 116.049 110.182 1.00 143.64 ? 508 GLU B N   1 
ATOM   5246  C CA  . GLU B 2 486 ? 202.081 116.834 108.957 1.00 143.64 ? 508 GLU B CA  1 
ATOM   5247  C C   . GLU B 2 486 ? 202.484 118.263 109.289 1.00 143.64 ? 508 GLU B C   1 
ATOM   5248  O O   . GLU B 2 486 ? 202.017 118.835 110.278 1.00 143.64 ? 508 GLU B O   1 
ATOM   5249  C CB  . GLU B 2 486 ? 200.726 116.822 108.241 1.00 143.64 ? 508 GLU B CB  1 
ATOM   5250  C CG  . GLU B 2 486 ? 200.248 115.437 107.826 1.00 143.64 ? 508 GLU B CG  1 
ATOM   5251  C CD  . GLU B 2 486 ? 200.917 114.939 106.558 1.00 143.64 ? 508 GLU B CD  1 
ATOM   5252  O OE1 . GLU B 2 486 ? 202.134 114.663 106.589 1.00 143.64 ? 508 GLU B OE1 1 
ATOM   5253  O OE2 . GLU B 2 486 ? 200.222 114.823 105.526 1.00 143.64 ? 508 GLU B OE2 1 
ATOM   5254  N N   . SER B 2 487 ? 203.349 118.837 108.457 1.00 141.84 ? 509 SER B N   1 
ATOM   5255  C CA  . SER B 2 487 ? 203.883 120.171 108.681 1.00 141.84 ? 509 SER B CA  1 
ATOM   5256  C C   . SER B 2 487 ? 203.360 121.135 107.625 1.00 141.84 ? 509 SER B C   1 
ATOM   5257  O O   . SER B 2 487 ? 203.096 120.749 106.482 1.00 141.84 ? 509 SER B O   1 
ATOM   5258  C CB  . SER B 2 487 ? 205.417 120.164 108.664 1.00 141.84 ? 509 SER B CB  1 
ATOM   5259  O OG  . SER B 2 487 ? 205.936 119.548 109.830 1.00 141.84 ? 509 SER B OG  1 
ATOM   5260  N N   . ILE B 2 488 ? 203.214 122.398 108.023 1.00 160.87 ? 510 ILE B N   1 
ATOM   5261  C CA  . ILE B 2 488 ? 202.747 123.450 107.129 1.00 160.87 ? 510 ILE B CA  1 
ATOM   5262  C C   . ILE B 2 488 ? 203.293 124.779 107.634 1.00 160.87 ? 510 ILE B C   1 
ATOM   5263  O O   . ILE B 2 488 ? 203.442 124.992 108.840 1.00 160.87 ? 510 ILE B O   1 
ATOM   5264  C CB  . ILE B 2 488 ? 201.201 123.467 107.026 1.00 160.87 ? 510 ILE B CB  1 
ATOM   5265  C CG1 . ILE B 2 488 ? 200.738 124.438 105.936 1.00 160.87 ? 510 ILE B CG1 1 
ATOM   5266  C CG2 . ILE B 2 488 ? 200.568 123.809 108.368 1.00 160.87 ? 510 ILE B CG2 1 
ATOM   5267  C CD1 . ILE B 2 488 ? 199.239 124.455 105.728 1.00 160.87 ? 510 ILE B CD1 1 
ATOM   5268  N N   . LYS B 2 489 ? 203.610 125.670 106.698 1.00 181.05 ? 511 LYS B N   1 
ATOM   5269  C CA  . LYS B 2 489 ? 204.167 126.976 107.010 1.00 181.05 ? 511 LYS B CA  1 
ATOM   5270  C C   . LYS B 2 489 ? 203.125 128.064 106.785 1.00 181.05 ? 511 LYS B C   1 
ATOM   5271  O O   . LYS B 2 489 ? 202.271 127.957 105.900 1.00 181.05 ? 511 LYS B O   1 
ATOM   5272  C CB  . LYS B 2 489 ? 205.409 127.263 106.160 1.00 181.05 ? 511 LYS B CB  1 
ATOM   5273  C CG  . LYS B 2 489 ? 206.502 126.216 106.286 1.00 181.05 ? 511 LYS B CG  1 
ATOM   5274  C CD  . LYS B 2 489 ? 207.681 126.538 105.383 1.00 181.05 ? 511 LYS B CD  1 
ATOM   5275  C CE  . LYS B 2 489 ? 208.758 125.471 105.482 1.00 181.05 ? 511 LYS B CE  1 
ATOM   5276  N NZ  . LYS B 2 489 ? 209.926 125.782 104.612 1.00 181.05 ? 511 LYS B NZ  1 
ATOM   5277  N N   . ALA B 2 490 ? 203.208 129.117 107.595 1.00 222.87 ? 512 ALA B N   1 
ATOM   5278  C CA  . ALA B 2 490 ? 202.283 130.238 107.497 1.00 222.87 ? 512 ALA B CA  1 
ATOM   5279  C C   . ALA B 2 490 ? 202.928 131.458 108.139 1.00 222.87 ? 512 ALA B C   1 
ATOM   5280  O O   . ALA B 2 490 ? 203.977 131.367 108.782 1.00 222.87 ? 512 ALA B O   1 
ATOM   5281  C CB  . ALA B 2 490 ? 200.938 129.915 108.156 1.00 222.87 ? 512 ALA B CB  1 
ATOM   5282  N N   . TYR B 2 491 ? 202.282 132.607 107.955 1.00 257.61 ? 513 TYR B N   1 
ATOM   5283  C CA  . TYR B 2 491 ? 202.748 133.869 108.508 1.00 257.61 ? 513 TYR B CA  1 
ATOM   5284  C C   . TYR B 2 491 ? 201.599 134.578 109.209 1.00 257.61 ? 513 TYR B C   1 
ATOM   5285  O O   . TYR B 2 491 ? 200.447 134.508 108.774 1.00 257.61 ? 513 TYR B O   1 
ATOM   5286  C CB  . TYR B 2 491 ? 203.330 134.783 107.420 1.00 257.61 ? 513 TYR B CB  1 
ATOM   5287  C CG  . TYR B 2 491 ? 204.735 134.426 106.995 1.00 257.61 ? 513 TYR B CG  1 
ATOM   5288  C CD1 . TYR B 2 491 ? 205.835 135.033 107.585 1.00 257.61 ? 513 TYR B CD1 1 
ATOM   5289  C CD2 . TYR B 2 491 ? 204.963 133.486 105.998 1.00 257.61 ? 513 TYR B CD2 1 
ATOM   5290  C CE1 . TYR B 2 491 ? 207.122 134.712 107.199 1.00 257.61 ? 513 TYR B CE1 1 
ATOM   5291  C CE2 . TYR B 2 491 ? 206.246 133.159 105.604 1.00 257.61 ? 513 TYR B CE2 1 
ATOM   5292  C CZ  . TYR B 2 491 ? 207.322 133.775 106.207 1.00 257.61 ? 513 TYR B CZ  1 
ATOM   5293  O OH  . TYR B 2 491 ? 208.602 133.452 105.820 1.00 257.61 ? 513 TYR B OH  1 
ATOM   5294  N N   . LEU B 2 492 ? 201.927 135.268 110.303 1.00 255.75 ? 514 LEU B N   1 
ATOM   5295  C CA  . LEU B 2 492 ? 200.916 136.037 111.021 1.00 255.75 ? 514 LEU B CA  1 
ATOM   5296  C C   . LEU B 2 492 ? 200.487 137.257 110.216 1.00 255.75 ? 514 LEU B C   1 
ATOM   5297  O O   . LEU B 2 492 ? 199.290 137.505 110.032 1.00 255.75 ? 514 LEU B O   1 
ATOM   5298  C CB  . LEU B 2 492 ? 201.447 136.451 112.393 1.00 255.75 ? 514 LEU B CB  1 
ATOM   5299  C CG  . LEU B 2 492 ? 200.435 137.098 113.342 1.00 255.75 ? 514 LEU B CG  1 
ATOM   5300  C CD1 . LEU B 2 492 ? 199.251 136.173 113.576 1.00 255.75 ? 514 LEU B CD1 1 
ATOM   5301  C CD2 . LEU B 2 492 ? 201.096 137.472 114.660 1.00 255.75 ? 514 LEU B CD2 1 
ATOM   5302  N N   . LYS B 2 493 ? 201.455 138.030 109.728 1.00 261.61 ? 515 LYS B N   1 
ATOM   5303  C CA  . LYS B 2 493 ? 201.171 139.176 108.867 1.00 261.61 ? 515 LYS B CA  1 
ATOM   5304  C C   . LYS B 2 493 ? 202.376 139.375 107.960 1.00 261.61 ? 515 LYS B C   1 
ATOM   5305  O O   . LYS B 2 493 ? 203.466 139.702 108.441 1.00 261.61 ? 515 LYS B O   1 
ATOM   5306  C CB  . LYS B 2 493 ? 200.881 140.430 109.687 1.00 261.61 ? 515 LYS B CB  1 
ATOM   5307  C CG  . LYS B 2 493 ? 200.467 141.630 108.851 1.00 261.61 ? 515 LYS B CG  1 
ATOM   5308  C CD  . LYS B 2 493 ? 200.082 142.811 109.726 1.00 261.61 ? 515 LYS B CD  1 
ATOM   5309  C CE  . LYS B 2 493 ? 199.639 143.998 108.886 1.00 261.61 ? 515 LYS B CE  1 
ATOM   5310  N NZ  . LYS B 2 493 ? 199.251 145.162 109.728 1.00 261.61 ? 515 LYS B NZ  1 
ATOM   5311  N N   . GLN B 2 494 ? 202.181 139.176 106.660 1.00 311.28 ? 516 GLN B N   1 
ATOM   5312  C CA  . GLN B 2 494 ? 203.283 139.271 105.715 1.00 311.28 ? 516 GLN B CA  1 
ATOM   5313  C C   . GLN B 2 494 ? 203.770 140.710 105.589 1.00 311.28 ? 516 GLN B C   1 
ATOM   5314  O O   . GLN B 2 494 ? 203.020 141.668 105.797 1.00 311.28 ? 516 GLN B O   1 
ATOM   5315  C CB  . GLN B 2 494 ? 202.860 138.737 104.347 1.00 311.28 ? 516 GLN B CB  1 
ATOM   5316  C CG  . GLN B 2 494 ? 202.615 137.237 104.322 1.00 311.28 ? 516 GLN B CG  1 
ATOM   5317  C CD  . GLN B 2 494 ? 202.092 136.753 102.984 1.00 311.28 ? 516 GLN B CD  1 
ATOM   5318  O OE1 . GLN B 2 494 ? 202.676 135.868 102.360 1.00 311.28 ? 516 GLN B OE1 1 
ATOM   5319  N NE2 . GLN B 2 494 ? 200.983 137.332 102.538 1.00 311.28 ? 516 GLN B NE2 1 
ATOM   5320  N N   . ALA B 2 495 ? 205.047 140.853 105.245 1.00 320.68 ? 517 ALA B N   1 
ATOM   5321  C CA  . ALA B 2 495 ? 205.690 142.152 105.118 1.00 320.68 ? 517 ALA B CA  1 
ATOM   5322  C C   . ALA B 2 495 ? 206.725 142.071 104.009 1.00 320.68 ? 517 ALA B C   1 
ATOM   5323  O O   . ALA B 2 495 ? 207.220 140.977 103.709 1.00 320.68 ? 517 ALA B O   1 
ATOM   5324  C CB  . ALA B 2 495 ? 206.352 142.583 106.435 1.00 320.68 ? 517 ALA B CB  1 
ATOM   5325  N N   . PRO B 2 496 ? 207.061 143.193 103.375 1.00 322.19 ? 518 PRO B N   1 
ATOM   5326  C CA  . PRO B 2 496 ? 208.095 143.161 102.346 1.00 322.19 ? 518 PRO B CA  1 
ATOM   5327  C C   . PRO B 2 496 ? 209.425 142.746 102.939 1.00 322.19 ? 518 PRO B C   1 
ATOM   5328  O O   . PRO B 2 496 ? 209.697 142.983 104.131 1.00 322.19 ? 518 PRO B O   1 
ATOM   5329  C CB  . PRO B 2 496 ? 208.131 144.609 101.837 1.00 322.19 ? 518 PRO B CB  1 
ATOM   5330  C CG  . PRO B 2 496 ? 206.795 145.167 102.181 1.00 322.19 ? 518 PRO B CG  1 
ATOM   5331  C CD  . PRO B 2 496 ? 206.416 144.513 103.473 1.00 322.19 ? 518 PRO B CD  1 
ATOM   5332  N N   . PRO B 2 497 ? 210.287 142.110 102.145 1.00 327.51 ? 519 PRO B N   1 
ATOM   5333  C CA  . PRO B 2 497 ? 211.584 141.666 102.667 1.00 327.51 ? 519 PRO B CA  1 
ATOM   5334  C C   . PRO B 2 497 ? 212.450 142.841 103.096 1.00 327.51 ? 519 PRO B C   1 
ATOM   5335  O O   . PRO B 2 497 ? 212.287 143.975 102.641 1.00 327.51 ? 519 PRO B O   1 
ATOM   5336  C CB  . PRO B 2 497 ? 212.209 140.916 101.483 1.00 327.51 ? 519 PRO B CB  1 
ATOM   5337  C CG  . PRO B 2 497 ? 211.057 140.571 100.590 1.00 327.51 ? 519 PRO B CG  1 
ATOM   5338  C CD  . PRO B 2 497 ? 210.079 141.693 100.749 1.00 327.51 ? 519 PRO B CD  1 
ATOM   5339  N N   . SER B 2 498 ? 213.392 142.549 103.996 1.00 337.24 ? 520 SER B N   1 
ATOM   5340  C CA  . SER B 2 498 ? 214.282 143.586 104.504 1.00 337.24 ? 520 SER B CA  1 
ATOM   5341  C C   . SER B 2 498 ? 215.422 143.885 103.540 1.00 337.24 ? 520 SER B C   1 
ATOM   5342  O O   . SER B 2 498 ? 215.916 145.018 103.506 1.00 337.24 ? 520 SER B O   1 
ATOM   5343  C CB  . SER B 2 498 ? 214.844 143.176 105.866 1.00 337.24 ? 520 SER B CB  1 
ATOM   5344  O OG  . SER B 2 498 ? 215.842 142.179 105.727 1.00 337.24 ? 520 SER B OG  1 
ATOM   5345  N N   . LYS B 2 499 ? 215.850 142.898 102.756 1.00 337.12 ? 521 LYS B N   1 
ATOM   5346  C CA  . LYS B 2 499 ? 216.929 143.081 101.799 1.00 337.12 ? 521 LYS B CA  1 
ATOM   5347  C C   . LYS B 2 499 ? 216.654 142.237 100.563 1.00 337.12 ? 521 LYS B C   1 
ATOM   5348  O O   . LYS B 2 499 ? 216.029 141.177 100.643 1.00 337.12 ? 521 LYS B O   1 
ATOM   5349  C CB  . LYS B 2 499 ? 218.293 142.714 102.406 1.00 337.12 ? 521 LYS B CB  1 
ATOM   5350  C CG  . LYS B 2 499 ? 218.372 141.308 102.989 1.00 337.12 ? 521 LYS B CG  1 
ATOM   5351  C CD  . LYS B 2 499 ? 219.023 140.333 102.017 1.00 337.12 ? 521 LYS B CD  1 
ATOM   5352  C CE  . LYS B 2 499 ? 219.085 138.930 102.597 1.00 337.12 ? 521 LYS B CE  1 
ATOM   5353  N NZ  . LYS B 2 499 ? 219.792 137.983 101.691 1.00 337.12 ? 521 LYS B NZ  1 
ATOM   5354  N N   . GLY B 2 500 ? 217.129 142.721 99.419  1.00 335.04 ? 522 GLY B N   1 
ATOM   5355  C CA  . GLY B 2 500 ? 216.952 142.025 98.168  1.00 335.04 ? 522 GLY B CA  1 
ATOM   5356  C C   . GLY B 2 500 ? 218.020 140.976 97.940  1.00 335.04 ? 522 GLY B C   1 
ATOM   5357  O O   . GLY B 2 500 ? 219.078 140.982 98.577  1.00 335.04 ? 522 GLY B O   1 
ATOM   5358  N N   . PRO B 2 501 ? 217.761 140.049 97.021  1.00 355.48 ? 523 PRO B N   1 
ATOM   5359  C CA  . PRO B 2 501 ? 218.737 138.990 96.752  1.00 355.48 ? 523 PRO B CA  1 
ATOM   5360  C C   . PRO B 2 501 ? 219.921 139.508 95.951  1.00 355.48 ? 523 PRO B C   1 
ATOM   5361  O O   . PRO B 2 501 ? 219.817 140.473 95.190  1.00 355.48 ? 523 PRO B O   1 
ATOM   5362  C CB  . PRO B 2 501 ? 217.932 137.962 95.951  1.00 355.48 ? 523 PRO B CB  1 
ATOM   5363  C CG  . PRO B 2 501 ? 216.878 138.771 95.273  1.00 355.48 ? 523 PRO B CG  1 
ATOM   5364  C CD  . PRO B 2 501 ? 216.539 139.901 96.211  1.00 355.48 ? 523 PRO B CD  1 
ATOM   5365  N N   . THR B 2 502 ? 221.059 138.846 96.133  1.00 363.66 ? 524 THR B N   1 
ATOM   5366  C CA  . THR B 2 502 ? 222.291 139.187 95.434  1.00 363.66 ? 524 THR B CA  1 
ATOM   5367  C C   . THR B 2 502 ? 222.423 138.322 94.188  1.00 363.66 ? 524 THR B C   1 
ATOM   5368  O O   . THR B 2 502 ? 222.254 137.100 94.254  1.00 363.66 ? 524 THR B O   1 
ATOM   5369  C CB  . THR B 2 502 ? 223.508 138.996 96.341  1.00 363.66 ? 524 THR B CB  1 
ATOM   5370  O OG1 . THR B 2 502 ? 223.859 137.607 96.386  1.00 363.66 ? 524 THR B OG1 1 
ATOM   5371  C CG2 . THR B 2 502 ? 223.203 139.482 97.750  1.00 363.66 ? 524 THR B CG2 1 
ATOM   5372  N N   . VAL B 2 503 ? 222.722 138.957 93.059  1.00 380.25 ? 525 VAL B N   1 
ATOM   5373  C CA  . VAL B 2 503 ? 222.838 138.265 91.785  1.00 380.25 ? 525 VAL B CA  1 
ATOM   5374  C C   . VAL B 2 503 ? 224.309 138.137 91.413  1.00 380.25 ? 525 VAL B C   1 
ATOM   5375  O O   . VAL B 2 503 ? 225.175 138.866 91.907  1.00 380.25 ? 525 VAL B O   1 
ATOM   5376  C CB  . VAL B 2 503 ? 222.051 138.979 90.666  1.00 380.25 ? 525 VAL B CB  1 
ATOM   5377  C CG1 . VAL B 2 503 ? 220.596 139.147 91.069  1.00 380.25 ? 525 VAL B CG1 1 
ATOM   5378  C CG2 . VAL B 2 503 ? 222.682 140.326 90.350  1.00 380.25 ? 525 VAL B CG2 1 
ATOM   5379  N N   . ARG B 2 504 ? 224.588 137.184 90.526  1.00 369.79 ? 526 ARG B N   1 
ATOM   5380  C CA  . ARG B 2 504 ? 225.937 136.952 90.035  1.00 369.79 ? 526 ARG B CA  1 
ATOM   5381  C C   . ARG B 2 504 ? 225.854 136.344 88.643  1.00 369.79 ? 526 ARG B C   1 
ATOM   5382  O O   . ARG B 2 504 ? 224.909 135.617 88.324  1.00 369.79 ? 526 ARG B O   1 
ATOM   5383  C CB  . ARG B 2 504 ? 226.733 136.036 90.973  1.00 369.79 ? 526 ARG B CB  1 
ATOM   5384  C CG  . ARG B 2 504 ? 226.031 134.732 91.312  1.00 369.79 ? 526 ARG B CG  1 
ATOM   5385  C CD  . ARG B 2 504 ? 226.858 133.893 92.271  1.00 369.79 ? 526 ARG B CD  1 
ATOM   5386  N NE  . ARG B 2 504 ? 226.131 132.715 92.734  1.00 369.79 ? 526 ARG B NE  1 
ATOM   5387  C CZ  . ARG B 2 504 ? 225.362 132.690 93.817  1.00 369.79 ? 526 ARG B CZ  1 
ATOM   5388  N NH1 . ARG B 2 504 ? 225.217 133.782 94.555  1.00 369.79 ? 526 ARG B NH1 1 
ATOM   5389  N NH2 . ARG B 2 504 ? 224.737 131.573 94.164  1.00 369.79 ? 526 ARG B NH2 1 
ATOM   5390  N N   . THR B 2 505 ? 226.852 136.649 87.819  1.00 339.14 ? 527 THR B N   1 
ATOM   5391  C CA  . THR B 2 505 ? 226.888 136.186 86.438  1.00 339.14 ? 527 THR B CA  1 
ATOM   5392  C C   . THR B 2 505 ? 227.580 134.830 86.373  1.00 339.14 ? 527 THR B C   1 
ATOM   5393  O O   . THR B 2 505 ? 228.721 134.686 86.826  1.00 339.14 ? 527 THR B O   1 
ATOM   5394  C CB  . THR B 2 505 ? 227.607 137.197 85.546  1.00 339.14 ? 527 THR B CB  1 
ATOM   5395  O OG1 . THR B 2 505 ? 228.995 137.247 85.900  1.00 339.14 ? 527 THR B OG1 1 
ATOM   5396  C CG2 . THR B 2 505 ? 226.997 138.581 85.710  1.00 339.14 ? 527 THR B CG2 1 
ATOM   5397  N N   . LYS B 2 506 ? 226.888 133.838 85.810  1.00 314.27 ? 528 LYS B N   1 
ATOM   5398  C CA  . LYS B 2 506 ? 227.482 132.517 85.637  1.00 314.27 ? 528 LYS B CA  1 
ATOM   5399  C C   . LYS B 2 506 ? 228.291 132.442 84.348  1.00 314.27 ? 528 LYS B C   1 
ATOM   5400  O O   . LYS B 2 506 ? 229.427 131.954 84.346  1.00 314.27 ? 528 LYS B O   1 
ATOM   5401  C CB  . LYS B 2 506 ? 226.391 131.444 85.647  1.00 314.27 ? 528 LYS B CB  1 
ATOM   5402  C CG  . LYS B 2 506 ? 225.799 131.169 87.018  1.00 314.27 ? 528 LYS B CG  1 
ATOM   5403  C CD  . LYS B 2 506 ? 224.646 130.180 86.933  1.00 314.27 ? 528 LYS B CD  1 
ATOM   5404  C CE  . LYS B 2 506 ? 225.054 128.913 86.199  1.00 314.27 ? 528 LYS B CE  1 
ATOM   5405  N NZ  . LYS B 2 506 ? 226.187 128.222 86.873  1.00 314.27 ? 528 LYS B NZ  1 
ATOM   5406  N N   . LYS B 2 507 ? 227.722 132.921 83.245  1.00 310.69 ? 529 LYS B N   1 
ATOM   5407  C CA  . LYS B 2 507 ? 228.406 132.919 81.957  1.00 310.69 ? 529 LYS B CA  1 
ATOM   5408  C C   . LYS B 2 507 ? 227.852 134.061 81.121  1.00 310.69 ? 529 LYS B C   1 
ATOM   5409  O O   . LYS B 2 507 ? 226.639 134.141 80.907  1.00 310.69 ? 529 LYS B O   1 
ATOM   5410  C CB  . LYS B 2 507 ? 228.225 131.581 81.236  1.00 310.69 ? 529 LYS B CB  1 
ATOM   5411  C CG  . LYS B 2 507 ? 229.358 131.221 80.286  1.00 310.69 ? 529 LYS B CG  1 
ATOM   5412  C CD  . LYS B 2 507 ? 229.140 131.817 78.904  1.00 310.69 ? 529 LYS B CD  1 
ATOM   5413  C CE  . LYS B 2 507 ? 230.258 131.430 77.950  1.00 310.69 ? 529 LYS B CE  1 
ATOM   5414  N NZ  . LYS B 2 507 ? 230.073 132.038 76.604  1.00 310.69 ? 529 LYS B NZ  1 
ATOM   5415  N N   . VAL B 2 508 ? 228.736 134.938 80.653  1.00 310.84 ? 530 VAL B N   1 
ATOM   5416  C CA  . VAL B 2 508 ? 228.362 136.086 79.835  1.00 310.84 ? 530 VAL B CA  1 
ATOM   5417  C C   . VAL B 2 508 ? 228.934 135.873 78.441  1.00 310.84 ? 530 VAL B C   1 
ATOM   5418  O O   . VAL B 2 508 ? 230.150 135.712 78.278  1.00 310.84 ? 530 VAL B O   1 
ATOM   5419  C CB  . VAL B 2 508 ? 228.863 137.404 80.444  1.00 310.84 ? 530 VAL B CB  1 
ATOM   5420  C CG1 . VAL B 2 508 ? 228.599 138.561 79.493  1.00 310.84 ? 530 VAL B CG1 1 
ATOM   5421  C CG2 . VAL B 2 508 ? 228.200 137.651 81.791  1.00 310.84 ? 530 VAL B CG2 1 
ATOM   5422  N N   . GLY B 2 509 ? 228.057 135.872 77.435  1.00 312.26 ? 531 GLY B N   1 
ATOM   5423  C CA  . GLY B 2 509 ? 228.443 135.673 76.064  1.00 312.26 ? 531 GLY B CA  1 
ATOM   5424  C C   . GLY B 2 509 ? 228.386 136.947 75.247  1.00 312.26 ? 531 GLY B C   1 
ATOM   5425  O O   . GLY B 2 509 ? 228.323 138.063 75.778  1.00 312.26 ? 531 GLY B O   1 
ATOM   5426  N N   . LYS B 2 510 ? 228.412 136.776 73.923  1.00 318.16 ? 532 LYS B N   1 
ATOM   5427  C CA  . LYS B 2 510 ? 228.361 137.929 73.030  1.00 318.16 ? 532 LYS B CA  1 
ATOM   5428  C C   . LYS B 2 510 ? 226.993 138.599 73.069  1.00 318.16 ? 532 LYS B C   1 
ATOM   5429  O O   . LYS B 2 510 ? 226.897 139.831 73.006  1.00 318.16 ? 532 LYS B O   1 
ATOM   5430  C CB  . LYS B 2 510 ? 228.709 137.502 71.604  1.00 318.16 ? 532 LYS B CB  1 
ATOM   5431  C CG  . LYS B 2 510 ? 229.997 136.703 71.494  1.00 318.16 ? 532 LYS B CG  1 
ATOM   5432  C CD  . LYS B 2 510 ? 230.228 136.219 70.071  1.00 318.16 ? 532 LYS B CD  1 
ATOM   5433  C CE  . LYS B 2 510 ? 231.453 135.324 69.984  1.00 318.16 ? 532 LYS B CE  1 
ATOM   5434  N NZ  . LYS B 2 510 ? 231.316 134.110 70.837  1.00 318.16 ? 532 LYS B NZ  1 
ATOM   5435  N N   . ASN B 2 511 ? 225.922 137.806 73.172  1.00 348.14 ? 533 ASN B N   1 
ATOM   5436  C CA  . ASN B 2 511 ? 224.574 138.359 73.223  1.00 348.14 ? 533 ASN B CA  1 
ATOM   5437  C C   . ASN B 2 511 ? 223.696 137.648 74.249  1.00 348.14 ? 533 ASN B C   1 
ATOM   5438  O O   . ASN B 2 511 ? 222.465 137.710 74.145  1.00 348.14 ? 533 ASN B O   1 
ATOM   5439  C CB  . ASN B 2 511 ? 223.909 138.296 71.843  1.00 348.14 ? 533 ASN B CB  1 
ATOM   5440  C CG  . ASN B 2 511 ? 223.722 136.874 71.349  1.00 348.14 ? 533 ASN B CG  1 
ATOM   5441  O OD1 . ASN B 2 511 ? 224.431 135.960 71.770  1.00 348.14 ? 533 ASN B OD1 1 
ATOM   5442  N ND2 . ASN B 2 511 ? 222.763 136.682 70.451  1.00 348.14 ? 533 ASN B ND2 1 
ATOM   5443  N N   . GLU B 2 512 ? 224.291 136.977 75.232  1.00 343.57 ? 534 GLU B N   1 
ATOM   5444  C CA  . GLU B 2 512 ? 223.530 136.242 76.231  1.00 343.57 ? 534 GLU B CA  1 
ATOM   5445  C C   . GLU B 2 512 ? 224.294 136.255 77.547  1.00 343.57 ? 534 GLU B C   1 
ATOM   5446  O O   . GLU B 2 512 ? 225.527 136.214 77.556  1.00 343.57 ? 534 GLU B O   1 
ATOM   5447  C CB  . GLU B 2 512 ? 223.268 134.800 75.779  1.00 343.57 ? 534 GLU B CB  1 
ATOM   5448  C CG  . GLU B 2 512 ? 222.182 134.084 76.565  1.00 343.57 ? 534 GLU B CG  1 
ATOM   5449  C CD  . GLU B 2 512 ? 222.727 133.339 77.766  1.00 343.57 ? 534 GLU B CD  1 
ATOM   5450  O OE1 . GLU B 2 512 ? 223.950 133.087 77.807  1.00 343.57 ? 534 GLU B OE1 1 
ATOM   5451  O OE2 . GLU B 2 512 ? 221.933 133.004 78.670  1.00 343.57 ? 534 GLU B OE2 1 
ATOM   5452  N N   . ALA B 2 513 ? 223.553 136.313 78.652  1.00 343.26 ? 535 ALA B N   1 
ATOM   5453  C CA  . ALA B 2 513 ? 224.142 136.334 79.984  1.00 343.26 ? 535 ALA B CA  1 
ATOM   5454  C C   . ALA B 2 513 ? 223.299 135.479 80.917  1.00 343.26 ? 535 ALA B C   1 
ATOM   5455  O O   . ALA B 2 513 ? 222.068 135.571 80.904  1.00 343.26 ? 535 ALA B O   1 
ATOM   5456  C CB  . ALA B 2 513 ? 224.246 137.764 80.524  1.00 343.26 ? 535 ALA B CB  1 
ATOM   5457  N N   . VAL B 2 514 ? 223.963 134.651 81.720  1.00 340.41 ? 536 VAL B N   1 
ATOM   5458  C CA  . VAL B 2 514 ? 223.300 133.772 82.676  1.00 340.41 ? 536 VAL B CA  1 
ATOM   5459  C C   . VAL B 2 514 ? 223.495 134.341 84.073  1.00 340.41 ? 536 VAL B C   1 
ATOM   5460  O O   . VAL B 2 514 ? 224.625 134.645 84.477  1.00 340.41 ? 536 VAL B O   1 
ATOM   5461  C CB  . VAL B 2 514 ? 223.848 132.337 82.585  1.00 340.41 ? 536 VAL B CB  1 
ATOM   5462  C CG1 . VAL B 2 514 ? 223.207 131.454 83.647  1.00 340.41 ? 536 VAL B CG1 1 
ATOM   5463  C CG2 . VAL B 2 514 ? 223.614 131.765 81.196  1.00 340.41 ? 536 VAL B CG2 1 
ATOM   5464  N N   . LEU B 2 515 ? 222.400 134.487 84.811  1.00 364.08 ? 537 LEU B N   1 
ATOM   5465  C CA  . LEU B 2 515 ? 222.435 135.011 86.167  1.00 364.08 ? 537 LEU B CA  1 
ATOM   5466  C C   . LEU B 2 515 ? 222.238 133.887 87.179  1.00 364.08 ? 537 LEU B C   1 
ATOM   5467  O O   . LEU B 2 515 ? 221.848 132.767 86.842  1.00 364.08 ? 537 LEU B O   1 
ATOM   5468  C CB  . LEU B 2 515 ? 221.366 136.093 86.360  1.00 364.08 ? 537 LEU B CB  1 
ATOM   5469  C CG  . LEU B 2 515 ? 221.273 137.199 85.306  1.00 364.08 ? 537 LEU B CG  1 
ATOM   5470  C CD1 . LEU B 2 515 ? 220.221 136.860 84.260  1.00 364.08 ? 537 LEU B CD1 1 
ATOM   5471  C CD2 . LEU B 2 515 ? 220.973 138.540 85.957  1.00 364.08 ? 537 LEU B CD2 1 
ATOM   5472  N N   . GLU B 2 516 ? 222.519 134.205 88.440  1.00 365.62 ? 538 GLU B N   1 
ATOM   5473  C CA  . GLU B 2 516 ? 222.365 133.253 89.530  1.00 365.62 ? 538 GLU B CA  1 
ATOM   5474  C C   . GLU B 2 516 ? 222.110 134.018 90.819  1.00 365.62 ? 538 GLU B C   1 
ATOM   5475  O O   . GLU B 2 516 ? 222.740 135.048 91.072  1.00 365.62 ? 538 GLU B O   1 
ATOM   5476  C CB  . GLU B 2 516 ? 223.603 132.361 89.679  1.00 365.62 ? 538 GLU B CB  1 
ATOM   5477  C CG  . GLU B 2 516 ? 223.433 131.221 90.670  1.00 365.62 ? 538 GLU B CG  1 
ATOM   5478  C CD  . GLU B 2 516 ? 224.680 130.367 90.794  1.00 365.62 ? 538 GLU B CD  1 
ATOM   5479  O OE1 . GLU B 2 516 ? 225.754 130.812 90.339  1.00 365.62 ? 538 GLU B OE1 1 
ATOM   5480  O OE2 . GLU B 2 516 ? 224.585 129.251 91.347  1.00 365.62 ? 538 GLU B OE2 1 
ATOM   5481  N N   . TRP B 2 517 ? 221.185 133.507 91.628  1.00 396.03 ? 539 TRP B N   1 
ATOM   5482  C CA  . TRP B 2 517 ? 220.855 134.128 92.900  1.00 396.03 ? 539 TRP B CA  1 
ATOM   5483  C C   . TRP B 2 517 ? 220.438 133.049 93.886  1.00 396.03 ? 539 TRP B C   1 
ATOM   5484  O O   . TRP B 2 517 ? 219.904 132.006 93.499  1.00 396.03 ? 539 TRP B O   1 
ATOM   5485  C CB  . TRP B 2 517 ? 219.739 135.170 92.748  1.00 396.03 ? 539 TRP B CB  1 
ATOM   5486  C CG  . TRP B 2 517 ? 218.483 134.623 92.139  1.00 396.03 ? 539 TRP B CG  1 
ATOM   5487  C CD1 . TRP B 2 517 ? 217.472 133.975 92.788  1.00 396.03 ? 539 TRP B CD1 1 
ATOM   5488  C CD2 . TRP B 2 517 ? 218.103 134.680 90.759  1.00 396.03 ? 539 TRP B CD2 1 
ATOM   5489  N NE1 . TRP B 2 517 ? 216.488 133.623 91.897  1.00 396.03 ? 539 TRP B NE1 1 
ATOM   5490  C CE2 . TRP B 2 517 ? 216.851 134.044 90.644  1.00 396.03 ? 539 TRP B CE2 1 
ATOM   5491  C CE3 . TRP B 2 517 ? 218.701 135.204 89.609  1.00 396.03 ? 539 TRP B CE3 1 
ATOM   5492  C CZ2 . TRP B 2 517 ? 216.185 133.920 89.427  1.00 396.03 ? 539 TRP B CZ2 1 
ATOM   5493  C CZ3 . TRP B 2 517 ? 218.038 135.080 88.401  1.00 396.03 ? 539 TRP B CZ3 1 
ATOM   5494  C CH2 . TRP B 2 517 ? 216.794 134.443 88.319  1.00 396.03 ? 539 TRP B CH2 1 
ATOM   5495  N N   . ASP B 2 518 ? 220.688 133.310 95.163  1.00 421.24 ? 540 ASP B N   1 
ATOM   5496  C CA  . ASP B 2 518 ? 220.331 132.397 96.237  1.00 421.24 ? 540 ASP B CA  1 
ATOM   5497  C C   . ASP B 2 518 ? 218.996 132.795 96.856  1.00 421.24 ? 540 ASP B C   1 
ATOM   5498  O O   . ASP B 2 518 ? 218.571 133.952 96.792  1.00 421.24 ? 540 ASP B O   1 
ATOM   5499  C CB  . ASP B 2 518 ? 221.426 132.365 97.308  1.00 421.24 ? 540 ASP B CB  1 
ATOM   5500  C CG  . ASP B 2 518 ? 221.672 133.726 97.935  1.00 421.24 ? 540 ASP B CG  1 
ATOM   5501  O OD1 . ASP B 2 518 ? 222.345 133.782 98.987  1.00 421.24 ? 540 ASP B OD1 1 
ATOM   5502  O OD2 . ASP B 2 518 ? 221.209 134.741 97.374  1.00 421.24 ? 540 ASP B OD2 1 
ATOM   5503  N N   . GLN B 2 519 ? 218.332 131.812 97.455  1.00 419.64 ? 541 GLN B N   1 
ATOM   5504  C CA  . GLN B 2 519 ? 217.060 132.068 98.114  1.00 419.64 ? 541 GLN B CA  1 
ATOM   5505  C C   . GLN B 2 519 ? 217.278 132.881 99.384  1.00 419.64 ? 541 GLN B C   1 
ATOM   5506  O O   . GLN B 2 519 ? 218.259 132.685 100.106 1.00 419.64 ? 541 GLN B O   1 
ATOM   5507  C CB  . GLN B 2 519 ? 216.356 130.752 98.442  1.00 419.64 ? 541 GLN B CB  1 
ATOM   5508  C CG  . GLN B 2 519 ? 216.182 129.826 97.247  1.00 419.64 ? 541 GLN B CG  1 
ATOM   5509  C CD  . GLN B 2 519 ? 215.280 130.413 96.178  1.00 419.64 ? 541 GLN B CD  1 
ATOM   5510  O OE1 . GLN B 2 519 ? 215.536 130.264 94.983  1.00 419.64 ? 541 GLN B OE1 1 
ATOM   5511  N NE2 . GLN B 2 519 ? 214.214 131.081 96.605  1.00 419.64 ? 541 GLN B NE2 1 
ATOM   5512  N N   . LEU B 2 520 ? 216.357 133.801 99.650  1.00 379.73 ? 542 LEU B N   1 
ATOM   5513  C CA  . LEU B 2 520 ? 216.483 134.652 100.822 1.00 379.73 ? 542 LEU B CA  1 
ATOM   5514  C C   . LEU B 2 520 ? 216.250 133.836 102.092 1.00 379.73 ? 542 LEU B C   1 
ATOM   5515  O O   . LEU B 2 520 ? 215.392 132.947 102.112 1.00 379.73 ? 542 LEU B O   1 
ATOM   5516  C CB  . LEU B 2 520 ? 215.488 135.810 100.757 1.00 379.73 ? 542 LEU B CB  1 
ATOM   5517  C CG  . LEU B 2 520 ? 215.709 136.838 99.646  1.00 379.73 ? 542 LEU B CG  1 
ATOM   5518  C CD1 . LEU B 2 520 ? 214.663 137.939 99.723  1.00 379.73 ? 542 LEU B CD1 1 
ATOM   5519  C CD2 . LEU B 2 520 ? 217.111 137.420 99.725  1.00 379.73 ? 542 LEU B CD2 1 
ATOM   5520  N N   . PRO B 2 521 ? 217.003 134.102 103.159 1.00 381.95 ? 543 PRO B N   1 
ATOM   5521  C CA  . PRO B 2 521 ? 216.770 133.391 104.420 1.00 381.95 ? 543 PRO B CA  1 
ATOM   5522  C C   . PRO B 2 521 ? 215.373 133.659 104.958 1.00 381.95 ? 543 PRO B C   1 
ATOM   5523  O O   . PRO B 2 521 ? 214.763 134.695 104.684 1.00 381.95 ? 543 PRO B O   1 
ATOM   5524  C CB  . PRO B 2 521 ? 217.847 133.957 105.354 1.00 381.95 ? 543 PRO B CB  1 
ATOM   5525  C CG  . PRO B 2 521 ? 218.903 134.492 104.440 1.00 381.95 ? 543 PRO B CG  1 
ATOM   5526  C CD  . PRO B 2 521 ? 218.173 134.993 103.230 1.00 381.95 ? 543 PRO B CD  1 
ATOM   5527  N N   . VAL B 2 522 ? 214.867 132.699 105.737 1.00 373.53 ? 544 VAL B N   1 
ATOM   5528  C CA  . VAL B 2 522 ? 213.514 132.799 106.270 1.00 373.53 ? 544 VAL B CA  1 
ATOM   5529  C C   . VAL B 2 522 ? 213.370 133.958 107.251 1.00 373.53 ? 544 VAL B C   1 
ATOM   5530  O O   . VAL B 2 522 ? 212.252 134.430 107.487 1.00 373.53 ? 544 VAL B O   1 
ATOM   5531  C CB  . VAL B 2 522 ? 213.109 131.463 106.924 1.00 373.53 ? 544 VAL B CB  1 
ATOM   5532  C CG1 . VAL B 2 522 ? 213.820 131.280 108.257 1.00 373.53 ? 544 VAL B CG1 1 
ATOM   5533  C CG2 . VAL B 2 522 ? 211.597 131.377 107.092 1.00 373.53 ? 544 VAL B CG2 1 
ATOM   5534  N N   . ASP B 2 523 ? 214.475 134.443 107.821 1.00 388.45 ? 545 ASP B N   1 
ATOM   5535  C CA  . ASP B 2 523 ? 214.408 135.551 108.765 1.00 388.45 ? 545 ASP B CA  1 
ATOM   5536  C C   . ASP B 2 523 ? 214.219 136.899 108.083 1.00 388.45 ? 545 ASP B C   1 
ATOM   5537  O O   . ASP B 2 523 ? 213.809 137.859 108.746 1.00 388.45 ? 545 ASP B O   1 
ATOM   5538  C CB  . ASP B 2 523 ? 215.671 135.585 109.628 1.00 388.45 ? 545 ASP B CB  1 
ATOM   5539  C CG  . ASP B 2 523 ? 215.720 134.451 110.632 1.00 388.45 ? 545 ASP B CG  1 
ATOM   5540  O OD1 . ASP B 2 523 ? 214.716 133.718 110.749 1.00 388.45 ? 545 ASP B OD1 1 
ATOM   5541  O OD2 . ASP B 2 523 ? 216.760 134.294 111.305 1.00 388.45 ? 545 ASP B OD2 1 
ATOM   5542  N N   . VAL B 2 524 ? 214.504 136.997 106.785 1.00 376.94 ? 546 VAL B N   1 
ATOM   5543  C CA  . VAL B 2 524 ? 214.381 138.249 106.048 1.00 376.94 ? 546 VAL B CA  1 
ATOM   5544  C C   . VAL B 2 524 ? 213.272 138.209 105.013 1.00 376.94 ? 546 VAL B C   1 
ATOM   5545  O O   . VAL B 2 524 ? 212.992 139.239 104.383 1.00 376.94 ? 546 VAL B O   1 
ATOM   5546  C CB  . VAL B 2 524 ? 215.714 138.639 105.381 1.00 376.94 ? 546 VAL B CB  1 
ATOM   5547  C CG1 . VAL B 2 524 ? 216.859 138.538 106.378 1.00 376.94 ? 546 VAL B CG1 1 
ATOM   5548  C CG2 . VAL B 2 524 ? 215.974 137.764 104.165 1.00 376.94 ? 546 VAL B CG2 1 
ATOM   5549  N N   . GLN B 2 525 ? 212.628 137.057 104.813 1.00 364.75 ? 547 GLN B N   1 
ATOM   5550  C CA  . GLN B 2 525 ? 211.558 136.978 103.824 1.00 364.75 ? 547 GLN B CA  1 
ATOM   5551  C C   . GLN B 2 525 ? 210.312 137.716 104.298 1.00 364.75 ? 547 GLN B C   1 
ATOM   5552  O O   . GLN B 2 525 ? 209.703 138.470 103.530 1.00 364.75 ? 547 GLN B O   1 
ATOM   5553  C CB  . GLN B 2 525 ? 211.232 135.516 103.516 1.00 364.75 ? 547 GLN B CB  1 
ATOM   5554  C CG  . GLN B 2 525 ? 212.252 134.829 102.624 1.00 364.75 ? 547 GLN B CG  1 
ATOM   5555  C CD  . GLN B 2 525 ? 211.883 133.390 102.318 1.00 364.75 ? 547 GLN B CD  1 
ATOM   5556  O OE1 . GLN B 2 525 ? 210.931 132.849 102.879 1.00 364.75 ? 547 GLN B OE1 1 
ATOM   5557  N NE2 . GLN B 2 525 ? 212.639 132.763 101.424 1.00 364.75 ? 547 GLN B NE2 1 
ATOM   5558  N N   . ASN B 2 526 ? 209.919 137.506 105.556 1.00 325.52 ? 548 ASN B N   1 
ATOM   5559  C CA  . ASN B 2 526 ? 208.770 138.182 106.163 1.00 325.52 ? 548 ASN B CA  1 
ATOM   5560  C C   . ASN B 2 526 ? 207.477 137.914 105.396 1.00 325.52 ? 548 ASN B C   1 
ATOM   5561  O O   . ASN B 2 526 ? 206.554 138.732 105.411 1.00 325.52 ? 548 ASN B O   1 
ATOM   5562  C CB  . ASN B 2 526 ? 209.015 139.690 106.288 1.00 325.52 ? 548 ASN B CB  1 
ATOM   5563  C CG  . ASN B 2 526 ? 210.356 140.012 106.916 1.00 325.52 ? 548 ASN B CG  1 
ATOM   5564  O OD1 . ASN B 2 526 ? 210.883 139.237 107.715 1.00 325.52 ? 548 ASN B OD1 1 
ATOM   5565  N ND2 . ASN B 2 526 ? 210.918 141.161 106.556 1.00 325.52 ? 548 ASN B ND2 1 
ATOM   5566  N N   . GLY B 2 527 ? 207.400 136.776 104.726 1.00 314.97 ? 549 GLY B N   1 
ATOM   5567  C CA  . GLY B 2 527 ? 206.211 136.425 103.979 1.00 314.97 ? 549 GLY B CA  1 
ATOM   5568  C C   . GLY B 2 527 ? 206.516 135.362 102.946 1.00 314.97 ? 549 GLY B C   1 
ATOM   5569  O O   . GLY B 2 527 ? 207.648 134.897 102.808 1.00 314.97 ? 549 GLY B O   1 
ATOM   5570  N N   . PHE B 2 528 ? 205.468 134.986 102.219 1.00 313.96 ? 550 PHE B N   1 
ATOM   5571  C CA  . PHE B 2 528 ? 205.566 133.978 101.168 1.00 313.96 ? 550 PHE B CA  1 
ATOM   5572  C C   . PHE B 2 528 ? 205.954 134.667 99.864  1.00 313.96 ? 550 PHE B C   1 
ATOM   5573  O O   . PHE B 2 528 ? 205.163 135.427 99.295  1.00 313.96 ? 550 PHE B O   1 
ATOM   5574  C CB  . PHE B 2 528 ? 204.249 133.221 101.019 1.00 313.96 ? 550 PHE B CB  1 
ATOM   5575  C CG  . PHE B 2 528 ? 204.012 132.200 102.094 1.00 313.96 ? 550 PHE B CG  1 
ATOM   5576  C CD1 . PHE B 2 528 ? 204.735 131.019 102.119 1.00 313.96 ? 550 PHE B CD1 1 
ATOM   5577  C CD2 . PHE B 2 528 ? 203.061 132.418 103.077 1.00 313.96 ? 550 PHE B CD2 1 
ATOM   5578  C CE1 . PHE B 2 528 ? 204.518 130.077 103.106 1.00 313.96 ? 550 PHE B CE1 1 
ATOM   5579  C CE2 . PHE B 2 528 ? 202.839 131.479 104.067 1.00 313.96 ? 550 PHE B CE2 1 
ATOM   5580  C CZ  . PHE B 2 528 ? 203.569 130.307 104.081 1.00 313.96 ? 550 PHE B CZ  1 
ATOM   5581  N N   . ILE B 2 529 ? 207.170 134.402 99.392  1.00 361.97 ? 551 ILE B N   1 
ATOM   5582  C CA  . ILE B 2 529 ? 207.638 134.987 98.140  1.00 361.97 ? 551 ILE B CA  1 
ATOM   5583  C C   . ILE B 2 529 ? 206.894 134.333 96.983  1.00 361.97 ? 551 ILE B C   1 
ATOM   5584  O O   . ILE B 2 529 ? 206.945 133.110 96.804  1.00 361.97 ? 551 ILE B O   1 
ATOM   5585  C CB  . ILE B 2 529 ? 209.155 134.825 97.990  1.00 361.97 ? 551 ILE B CB  1 
ATOM   5586  C CG1 . ILE B 2 529 ? 209.877 135.418 99.202  1.00 361.97 ? 551 ILE B CG1 1 
ATOM   5587  C CG2 . ILE B 2 529 ? 209.633 135.484 96.707  1.00 361.97 ? 551 ILE B CG2 1 
ATOM   5588  C CD1 . ILE B 2 529 ? 209.606 136.891 99.414  1.00 361.97 ? 551 ILE B CD1 1 
ATOM   5589  N N   . ARG B 2 530 ? 206.199 135.147 96.191  1.00 385.89 ? 552 ARG B N   1 
ATOM   5590  C CA  . ARG B 2 530 ? 205.406 134.641 95.078  1.00 385.89 ? 552 ARG B CA  1 
ATOM   5591  C C   . ARG B 2 530 ? 206.206 134.585 93.780  1.00 385.89 ? 552 ARG B C   1 
ATOM   5592  O O   . ARG B 2 530 ? 206.259 133.539 93.126  1.00 385.89 ? 552 ARG B O   1 
ATOM   5593  C CB  . ARG B 2 530 ? 204.153 135.503 94.893  1.00 385.89 ? 552 ARG B CB  1 
ATOM   5594  C CG  . ARG B 2 530 ? 203.226 135.525 96.100  1.00 385.89 ? 552 ARG B CG  1 
ATOM   5595  C CD  . ARG B 2 530 ? 202.522 134.189 96.292  1.00 385.89 ? 552 ARG B CD  1 
ATOM   5596  N NE  . ARG B 2 530 ? 203.263 133.296 97.179  1.00 385.89 ? 552 ARG B NE  1 
ATOM   5597  C CZ  . ARG B 2 530 ? 202.891 132.054 97.469  1.00 385.89 ? 552 ARG B CZ  1 
ATOM   5598  N NH1 . ARG B 2 530 ? 201.783 131.551 96.943  1.00 385.89 ? 552 ARG B NH1 1 
ATOM   5599  N NH2 . ARG B 2 530 ? 203.627 131.313 98.286  1.00 385.89 ? 552 ARG B NH2 1 
ATOM   5600  N N   . ASN B 2 531 ? 206.831 135.695 93.397  1.00 394.90 ? 553 ASN B N   1 
ATOM   5601  C CA  . ASN B 2 531 ? 207.601 135.750 92.164  1.00 394.90 ? 553 ASN B CA  1 
ATOM   5602  C C   . ASN B 2 531 ? 208.734 136.753 92.329  1.00 394.90 ? 553 ASN B C   1 
ATOM   5603  O O   . ASN B 2 531 ? 208.760 137.546 93.273  1.00 394.90 ? 553 ASN B O   1 
ATOM   5604  C CB  . ASN B 2 531 ? 206.717 136.116 90.966  1.00 394.90 ? 553 ASN B CB  1 
ATOM   5605  C CG  . ASN B 2 531 ? 205.768 137.261 91.269  1.00 394.90 ? 553 ASN B CG  1 
ATOM   5606  O OD1 . ASN B 2 531 ? 205.909 137.949 92.280  1.00 394.90 ? 553 ASN B OD1 1 
ATOM   5607  N ND2 . ASN B 2 531 ? 204.795 137.470 90.391  1.00 394.90 ? 553 ASN B ND2 1 
ATOM   5608  N N   . TYR B 2 532 ? 209.676 136.707 91.391  1.00 399.27 ? 554 TYR B N   1 
ATOM   5609  C CA  . TYR B 2 532 ? 210.827 137.594 91.383  1.00 399.27 ? 554 TYR B CA  1 
ATOM   5610  C C   . TYR B 2 532 ? 210.827 138.434 90.112  1.00 399.27 ? 554 TYR B C   1 
ATOM   5611  O O   . TYR B 2 532 ? 210.129 138.133 89.140  1.00 399.27 ? 554 TYR B O   1 
ATOM   5612  C CB  . TYR B 2 532 ? 212.141 136.808 91.485  1.00 399.27 ? 554 TYR B CB  1 
ATOM   5613  C CG  . TYR B 2 532 ? 212.342 136.106 92.808  1.00 399.27 ? 554 TYR B CG  1 
ATOM   5614  C CD1 . TYR B 2 532 ? 212.629 136.825 93.961  1.00 399.27 ? 554 TYR B CD1 1 
ATOM   5615  C CD2 . TYR B 2 532 ? 212.254 134.724 92.903  1.00 399.27 ? 554 TYR B CD2 1 
ATOM   5616  C CE1 . TYR B 2 532 ? 212.818 136.186 95.172  1.00 399.27 ? 554 TYR B CE1 1 
ATOM   5617  C CE2 . TYR B 2 532 ? 212.442 134.077 94.109  1.00 399.27 ? 554 TYR B CE2 1 
ATOM   5618  C CZ  . TYR B 2 532 ? 212.724 134.813 95.240  1.00 399.27 ? 554 TYR B CZ  1 
ATOM   5619  O OH  . TYR B 2 532 ? 212.910 134.173 96.444  1.00 399.27 ? 554 TYR B OH  1 
ATOM   5620  N N   . THR B 2 533 ? 211.625 139.499 90.133  1.00 410.49 ? 555 THR B N   1 
ATOM   5621  C CA  . THR B 2 533 ? 211.770 140.385 88.988  1.00 410.49 ? 555 THR B CA  1 
ATOM   5622  C C   . THR B 2 533 ? 213.215 140.851 88.894  1.00 410.49 ? 555 THR B C   1 
ATOM   5623  O O   . THR B 2 533 ? 213.923 140.942 89.901  1.00 410.49 ? 555 THR B O   1 
ATOM   5624  C CB  . THR B 2 533 ? 210.824 141.593 89.079  1.00 410.49 ? 555 THR B CB  1 
ATOM   5625  O OG1 . THR B 2 533 ? 210.908 142.363 87.872  1.00 410.49 ? 555 THR B OG1 1 
ATOM   5626  C CG2 . THR B 2 533 ? 211.178 142.472 90.270  1.00 410.49 ? 555 THR B CG2 1 
ATOM   5627  N N   . ILE B 2 534 ? 213.650 141.135 87.669  1.00 421.10 ? 556 ILE B N   1 
ATOM   5628  C CA  . ILE B 2 534 ? 215.012 141.577 87.393  1.00 421.10 ? 556 ILE B CA  1 
ATOM   5629  C C   . ILE B 2 534 ? 214.944 142.868 86.591  1.00 421.10 ? 556 ILE B C   1 
ATOM   5630  O O   . ILE B 2 534 ? 214.295 142.917 85.540  1.00 421.10 ? 556 ILE B O   1 
ATOM   5631  C CB  . ILE B 2 534 ? 215.820 140.509 86.631  1.00 421.10 ? 556 ILE B CB  1 
ATOM   5632  C CG1 . ILE B 2 534 ? 215.937 139.230 87.463  1.00 421.10 ? 556 ILE B CG1 1 
ATOM   5633  C CG2 . ILE B 2 534 ? 217.198 141.040 86.267  1.00 421.10 ? 556 ILE B CG2 1 
ATOM   5634  C CD1 . ILE B 2 534 ? 216.696 138.118 86.773  1.00 421.10 ? 556 ILE B CD1 1 
ATOM   5635  N N   . PHE B 2 535 ? 215.612 143.907 87.083  1.00 434.64 ? 557 PHE B N   1 
ATOM   5636  C CA  . PHE B 2 535 ? 215.647 145.213 86.430  1.00 434.64 ? 557 PHE B CA  1 
ATOM   5637  C C   . PHE B 2 535 ? 217.040 145.416 85.843  1.00 434.64 ? 557 PHE B C   1 
ATOM   5638  O O   . PHE B 2 535 ? 217.971 145.809 86.552  1.00 434.64 ? 557 PHE B O   1 
ATOM   5639  C CB  . PHE B 2 535 ? 215.292 146.327 87.410  1.00 434.64 ? 557 PHE B CB  1 
ATOM   5640  C CG  . PHE B 2 535 ? 213.882 146.259 87.924  1.00 434.64 ? 557 PHE B CG  1 
ATOM   5641  C CD1 . PHE B 2 535 ? 212.817 146.622 87.116  1.00 434.64 ? 557 PHE B CD1 1 
ATOM   5642  C CD2 . PHE B 2 535 ? 213.623 145.840 89.218  1.00 434.64 ? 557 PHE B CD2 1 
ATOM   5643  C CE1 . PHE B 2 535 ? 211.519 146.563 87.588  1.00 434.64 ? 557 PHE B CE1 1 
ATOM   5644  C CE2 . PHE B 2 535 ? 212.327 145.779 89.696  1.00 434.64 ? 557 PHE B CE2 1 
ATOM   5645  C CZ  . PHE B 2 535 ? 211.274 146.141 88.879  1.00 434.64 ? 557 PHE B CZ  1 
ATOM   5646  N N   . TYR B 2 536 ? 217.178 145.150 84.548  1.00 439.51 ? 558 TYR B N   1 
ATOM   5647  C CA  . TYR B 2 536 ? 218.419 145.380 83.821  1.00 439.51 ? 558 TYR B CA  1 
ATOM   5648  C C   . TYR B 2 536 ? 218.232 146.573 82.894  1.00 439.51 ? 558 TYR B C   1 
ATOM   5649  O O   . TYR B 2 536 ? 217.235 146.651 82.168  1.00 439.51 ? 558 TYR B O   1 
ATOM   5650  C CB  . TYR B 2 536 ? 218.838 144.137 83.028  1.00 439.51 ? 558 TYR B CB  1 
ATOM   5651  C CG  . TYR B 2 536 ? 217.840 143.683 81.985  1.00 439.51 ? 558 TYR B CG  1 
ATOM   5652  C CD1 . TYR B 2 536 ? 216.738 142.913 82.337  1.00 439.51 ? 558 TYR B CD1 1 
ATOM   5653  C CD2 . TYR B 2 536 ? 218.006 144.015 80.646  1.00 439.51 ? 558 TYR B CD2 1 
ATOM   5654  C CE1 . TYR B 2 536 ? 215.826 142.494 81.386  1.00 439.51 ? 558 TYR B CE1 1 
ATOM   5655  C CE2 . TYR B 2 536 ? 217.099 143.600 79.689  1.00 439.51 ? 558 TYR B CE2 1 
ATOM   5656  C CZ  . TYR B 2 536 ? 216.012 142.840 80.064  1.00 439.51 ? 558 TYR B CZ  1 
ATOM   5657  O OH  . TYR B 2 536 ? 215.107 142.425 79.114  1.00 439.51 ? 558 TYR B OH  1 
ATOM   5658  N N   . ARG B 2 537 ? 219.183 147.504 82.930  1.00 431.69 ? 559 ARG B N   1 
ATOM   5659  C CA  . ARG B 2 537 ? 219.083 148.743 82.175  1.00 431.69 ? 559 ARG B CA  1 
ATOM   5660  C C   . ARG B 2 537 ? 220.442 149.077 81.575  1.00 431.69 ? 559 ARG B C   1 
ATOM   5661  O O   . ARG B 2 537 ? 221.436 148.378 81.798  1.00 431.69 ? 559 ARG B O   1 
ATOM   5662  C CB  . ARG B 2 537 ? 218.578 149.889 83.059  1.00 431.69 ? 559 ARG B CB  1 
ATOM   5663  C CG  . ARG B 2 537 ? 219.481 150.202 84.240  1.00 431.69 ? 559 ARG B CG  1 
ATOM   5664  C CD  . ARG B 2 537 ? 218.953 151.375 85.049  1.00 431.69 ? 559 ARG B CD  1 
ATOM   5665  N NE  . ARG B 2 537 ? 219.808 151.675 86.194  1.00 431.69 ? 559 ARG B NE  1 
ATOM   5666  C CZ  . ARG B 2 537 ? 219.588 152.665 87.053  1.00 431.69 ? 559 ARG B CZ  1 
ATOM   5667  N NH1 . ARG B 2 537 ? 218.537 153.458 86.899  1.00 431.69 ? 559 ARG B NH1 1 
ATOM   5668  N NH2 . ARG B 2 537 ? 220.421 152.863 88.066  1.00 431.69 ? 559 ARG B NH2 1 
ATOM   5669  N N   . THR B 2 538 ? 220.476 150.160 80.806  1.00 396.43 ? 560 THR B N   1 
ATOM   5670  C CA  . THR B 2 538 ? 221.691 150.666 80.189  1.00 396.43 ? 560 THR B CA  1 
ATOM   5671  C C   . THR B 2 538 ? 221.953 152.081 80.690  1.00 396.43 ? 560 THR B C   1 
ATOM   5672  O O   . THR B 2 538 ? 221.035 152.792 81.107  1.00 396.43 ? 560 THR B O   1 
ATOM   5673  C CB  . THR B 2 538 ? 221.582 150.652 78.655  1.00 396.43 ? 560 THR B CB  1 
ATOM   5674  O OG1 . THR B 2 538 ? 220.934 149.446 78.233  1.00 396.43 ? 560 THR B OG1 1 
ATOM   5675  C CG2 . THR B 2 538 ? 222.961 150.716 78.014  1.00 396.43 ? 560 THR B CG2 1 
ATOM   5676  N N   . ILE B 2 539 ? 223.228 152.479 80.660  1.00 353.75 ? 561 ILE B N   1 
ATOM   5677  C CA  . ILE B 2 539 ? 223.601 153.820 81.103  1.00 353.75 ? 561 ILE B CA  1 
ATOM   5678  C C   . ILE B 2 539 ? 222.885 154.876 80.270  1.00 353.75 ? 561 ILE B C   1 
ATOM   5679  O O   . ILE B 2 539 ? 222.485 155.929 80.782  1.00 353.75 ? 561 ILE B O   1 
ATOM   5680  C CB  . ILE B 2 539 ? 225.130 153.996 81.048  1.00 353.75 ? 561 ILE B CB  1 
ATOM   5681  C CG1 . ILE B 2 539 ? 225.825 152.821 81.742  1.00 353.75 ? 561 ILE B CG1 1 
ATOM   5682  C CG2 . ILE B 2 539 ? 225.539 155.315 81.688  1.00 353.75 ? 561 ILE B CG2 1 
ATOM   5683  C CD1 . ILE B 2 539 ? 227.299 153.045 82.002  1.00 353.75 ? 561 ILE B CD1 1 
ATOM   5684  N N   . ILE B 2 540 ? 222.705 154.611 78.976  1.00 341.14 ? 562 ILE B N   1 
ATOM   5685  C CA  . ILE B 2 540 ? 221.996 155.524 78.097  1.00 341.14 ? 562 ILE B CA  1 
ATOM   5686  C C   . ILE B 2 540 ? 220.577 155.052 77.789  1.00 341.14 ? 562 ILE B C   1 
ATOM   5687  O O   . ILE B 2 540 ? 219.681 155.890 77.631  1.00 341.14 ? 562 ILE B O   1 
ATOM   5688  C CB  . ILE B 2 540 ? 222.789 155.753 76.793  1.00 341.14 ? 562 ILE B CB  1 
ATOM   5689  C CG1 . ILE B 2 540 ? 224.277 155.952 77.092  1.00 341.14 ? 562 ILE B CG1 1 
ATOM   5690  C CG2 . ILE B 2 540 ? 222.241 156.953 76.035  1.00 341.14 ? 562 ILE B CG2 1 
ATOM   5691  C CD1 . ILE B 2 540 ? 224.569 157.108 78.028  1.00 341.14 ? 562 ILE B CD1 1 
ATOM   5692  N N   . GLY B 2 541 ? 220.343 153.743 77.708  1.00 363.77 ? 563 GLY B N   1 
ATOM   5693  C CA  . GLY B 2 541 ? 219.033 153.222 77.384  1.00 363.77 ? 563 GLY B CA  1 
ATOM   5694  C C   . GLY B 2 541 ? 218.065 153.286 78.551  1.00 363.77 ? 563 GLY B C   1 
ATOM   5695  O O   . GLY B 2 541 ? 218.371 153.771 79.640  1.00 363.77 ? 563 GLY B O   1 
ATOM   5696  N N   . ASN B 2 542 ? 216.862 152.777 78.304  1.00 388.33 ? 564 ASN B N   1 
ATOM   5697  C CA  . ASN B 2 542 ? 215.798 152.772 79.295  1.00 388.33 ? 564 ASN B CA  1 
ATOM   5698  C C   . ASN B 2 542 ? 215.822 151.481 80.109  1.00 388.33 ? 564 ASN B C   1 
ATOM   5699  O O   . ASN B 2 542 ? 216.416 150.475 79.712  1.00 388.33 ? 564 ASN B O   1 
ATOM   5700  C CB  . ASN B 2 542 ? 214.436 152.944 78.619  1.00 388.33 ? 564 ASN B CB  1 
ATOM   5701  C CG  . ASN B 2 542 ? 213.362 153.418 79.579  1.00 388.33 ? 564 ASN B CG  1 
ATOM   5702  O OD1 . ASN B 2 542 ? 213.659 154.001 80.622  1.00 388.33 ? 564 ASN B OD1 1 
ATOM   5703  N ND2 . ASN B 2 542 ? 212.105 153.170 79.231  1.00 388.33 ? 564 ASN B ND2 1 
ATOM   5704  N N   . GLU B 2 543 ? 215.164 151.524 81.264  1.00 424.88 ? 565 GLU B N   1 
ATOM   5705  C CA  . GLU B 2 543 ? 215.101 150.384 82.169  1.00 424.88 ? 565 GLU B CA  1 
ATOM   5706  C C   . GLU B 2 543 ? 213.898 149.514 81.830  1.00 424.88 ? 565 GLU B C   1 
ATOM   5707  O O   . GLU B 2 543 ? 212.788 150.022 81.643  1.00 424.88 ? 565 GLU B O   1 
ATOM   5708  C CB  . GLU B 2 543 ? 215.023 150.855 83.622  1.00 424.88 ? 565 GLU B CB  1 
ATOM   5709  C CG  . GLU B 2 543 ? 214.866 149.731 84.634  1.00 424.88 ? 565 GLU B CG  1 
ATOM   5710  C CD  . GLU B 2 543 ? 214.806 150.239 86.062  1.00 424.88 ? 565 GLU B CD  1 
ATOM   5711  O OE1 . GLU B 2 543 ? 215.236 151.385 86.305  1.00 424.88 ? 565 GLU B OE1 1 
ATOM   5712  O OE2 . GLU B 2 543 ? 214.327 149.491 86.940  1.00 424.88 ? 565 GLU B OE2 1 
ATOM   5713  N N   . THR B 2 544 ? 214.123 148.204 81.752  1.00 425.19 ? 566 THR B N   1 
ATOM   5714  C CA  . THR B 2 544 ? 213.076 147.240 81.455  1.00 425.19 ? 566 THR B CA  1 
ATOM   5715  C C   . THR B 2 544 ? 212.892 146.291 82.633  1.00 425.19 ? 566 THR B C   1 
ATOM   5716  O O   . THR B 2 544 ? 213.745 146.190 83.518  1.00 425.19 ? 566 THR B O   1 
ATOM   5717  C CB  . THR B 2 544 ? 213.396 146.435 80.187  1.00 425.19 ? 566 THR B CB  1 
ATOM   5718  O OG1 . THR B 2 544 ? 214.339 145.402 80.499  1.00 425.19 ? 566 THR B OG1 1 
ATOM   5719  C CG2 . THR B 2 544 ? 213.979 147.339 79.111  1.00 425.19 ? 566 THR B CG2 1 
ATOM   5720  N N   . ALA B 2 545 ? 211.758 145.593 82.631  1.00 394.11 ? 567 ALA B N   1 
ATOM   5721  C CA  . ALA B 2 545 ? 211.424 144.637 83.675  1.00 394.11 ? 567 ALA B CA  1 
ATOM   5722  C C   . ALA B 2 545 ? 211.107 143.286 83.050  1.00 394.11 ? 567 ALA B C   1 
ATOM   5723  O O   . ALA B 2 545 ? 210.687 143.202 81.892  1.00 394.11 ? 567 ALA B O   1 
ATOM   5724  C CB  . ALA B 2 545 ? 210.234 145.114 84.518  1.00 394.11 ? 567 ALA B CB  1 
ATOM   5725  N N   . VAL B 2 546 ? 211.313 142.228 83.829  1.00 403.87 ? 568 VAL B N   1 
ATOM   5726  C CA  . VAL B 2 546 ? 211.060 140.865 83.376  1.00 403.87 ? 568 VAL B CA  1 
ATOM   5727  C C   . VAL B 2 546 ? 210.546 140.056 84.559  1.00 403.87 ? 568 VAL B C   1 
ATOM   5728  O O   . VAL B 2 546 ? 210.986 140.246 85.697  1.00 403.87 ? 568 VAL B O   1 
ATOM   5729  C CB  . VAL B 2 546 ? 212.328 140.235 82.755  1.00 403.87 ? 568 VAL B CB  1 
ATOM   5730  C CG1 . VAL B 2 546 ? 213.483 140.255 83.746  1.00 403.87 ? 568 VAL B CG1 1 
ATOM   5731  C CG2 . VAL B 2 546 ? 212.051 138.820 82.266  1.00 403.87 ? 568 VAL B CG2 1 
ATOM   5732  N N   . ASN B 2 547 ? 209.600 139.160 84.289  1.00 417.76 ? 569 ASN B N   1 
ATOM   5733  C CA  . ASN B 2 547 ? 208.985 138.333 85.317  1.00 417.76 ? 569 ASN B CA  1 
ATOM   5734  C C   . ASN B 2 547 ? 209.639 136.957 85.331  1.00 417.76 ? 569 ASN B C   1 
ATOM   5735  O O   . ASN B 2 547 ? 210.003 136.418 84.281  1.00 417.76 ? 569 ASN B O   1 
ATOM   5736  C CB  . ASN B 2 547 ? 207.477 138.202 85.075  1.00 417.76 ? 569 ASN B CB  1 
ATOM   5737  C CG  . ASN B 2 547 ? 206.746 137.526 86.228  1.00 417.76 ? 569 ASN B CG  1 
ATOM   5738  O OD1 . ASN B 2 547 ? 207.200 136.519 86.774  1.00 417.76 ? 569 ASN B OD1 1 
ATOM   5739  N ND2 . ASN B 2 547 ? 205.601 138.084 86.602  1.00 417.76 ? 569 ASN B ND2 1 
ATOM   5740  N N   . VAL B 2 548 ? 209.785 136.395 86.528  1.00 408.90 ? 570 VAL B N   1 
ATOM   5741  C CA  . VAL B 2 548 ? 210.348 135.060 86.703  1.00 408.90 ? 570 VAL B CA  1 
ATOM   5742  C C   . VAL B 2 548 ? 209.755 134.453 87.967  1.00 408.90 ? 570 VAL B C   1 
ATOM   5743  O O   . VAL B 2 548 ? 209.557 135.144 88.972  1.00 408.90 ? 570 VAL B O   1 
ATOM   5744  C CB  . VAL B 2 548 ? 211.893 135.096 86.750  1.00 408.90 ? 570 VAL B CB  1 
ATOM   5745  C CG1 . VAL B 2 548 ? 212.386 135.894 87.949  1.00 408.90 ? 570 VAL B CG1 1 
ATOM   5746  C CG2 . VAL B 2 548 ? 212.462 133.684 86.769  1.00 408.90 ? 570 VAL B CG2 1 
ATOM   5747  N N   . ASP B 2 549 ? 209.449 133.160 87.905  1.00 403.47 ? 571 ASP B N   1 
ATOM   5748  C CA  . ASP B 2 549 ? 208.846 132.478 89.039  1.00 403.47 ? 571 ASP B CA  1 
ATOM   5749  C C   . ASP B 2 549 ? 209.875 132.248 90.143  1.00 403.47 ? 571 ASP B C   1 
ATOM   5750  O O   . ASP B 2 549 ? 211.089 132.310 89.927  1.00 403.47 ? 571 ASP B O   1 
ATOM   5751  C CB  . ASP B 2 549 ? 208.238 131.145 88.602  1.00 403.47 ? 571 ASP B CB  1 
ATOM   5752  C CG  . ASP B 2 549 ? 207.123 131.317 87.590  1.00 403.47 ? 571 ASP B CG  1 
ATOM   5753  O OD1 . ASP B 2 549 ? 206.440 132.362 87.628  1.00 403.47 ? 571 ASP B OD1 1 
ATOM   5754  O OD2 . ASP B 2 549 ? 206.928 130.407 86.757  1.00 403.47 ? 571 ASP B OD2 1 
ATOM   5755  N N   . SER B 2 550 ? 209.367 131.978 91.347  1.00 400.98 ? 572 SER B N   1 
ATOM   5756  C CA  . SER B 2 550 ? 210.231 131.730 92.494  1.00 400.98 ? 572 SER B CA  1 
ATOM   5757  C C   . SER B 2 550 ? 210.864 130.346 92.468  1.00 400.98 ? 572 SER B C   1 
ATOM   5758  O O   . SER B 2 550 ? 211.867 130.127 93.156  1.00 400.98 ? 572 SER B O   1 
ATOM   5759  C CB  . SER B 2 550 ? 209.445 131.909 93.795  1.00 400.98 ? 572 SER B CB  1 
ATOM   5760  O OG  . SER B 2 550 ? 209.000 133.246 93.943  1.00 400.98 ? 572 SER B OG  1 
ATOM   5761  N N   . SER B 2 551 ? 210.307 129.411 91.695  1.00 409.09 ? 573 SER B N   1 
ATOM   5762  C CA  . SER B 2 551 ? 210.873 128.070 91.624  1.00 409.09 ? 573 SER B CA  1 
ATOM   5763  C C   . SER B 2 551 ? 212.193 128.036 90.867  1.00 409.09 ? 573 SER B C   1 
ATOM   5764  O O   . SER B 2 551 ? 212.944 127.064 91.000  1.00 409.09 ? 573 SER B O   1 
ATOM   5765  C CB  . SER B 2 551 ? 209.875 127.111 90.971  1.00 409.09 ? 573 SER B CB  1 
ATOM   5766  O OG  . SER B 2 551 ? 209.859 127.272 89.564  1.00 409.09 ? 573 SER B OG  1 
ATOM   5767  N N   . HIS B 2 552 ? 212.492 129.065 90.081  1.00 401.29 ? 574 HIS B N   1 
ATOM   5768  C CA  . HIS B 2 552 ? 213.732 129.141 89.323  1.00 401.29 ? 574 HIS B CA  1 
ATOM   5769  C C   . HIS B 2 552 ? 214.716 130.068 90.024  1.00 401.29 ? 574 HIS B C   1 
ATOM   5770  O O   . HIS B 2 552 ? 214.335 131.128 90.529  1.00 401.29 ? 574 HIS B O   1 
ATOM   5771  C CB  . HIS B 2 552 ? 213.473 129.636 87.899  1.00 401.29 ? 574 HIS B CB  1 
ATOM   5772  C CG  . HIS B 2 552 ? 212.339 128.940 87.213  1.00 401.29 ? 574 HIS B CG  1 
ATOM   5773  N ND1 . HIS B 2 552 ? 211.018 129.260 87.447  1.00 401.29 ? 574 HIS B ND1 1 
ATOM   5774  C CD2 . HIS B 2 552 ? 212.327 127.941 86.299  1.00 401.29 ? 574 HIS B CD2 1 
ATOM   5775  C CE1 . HIS B 2 552 ? 210.243 128.488 86.707  1.00 401.29 ? 574 HIS B CE1 1 
ATOM   5776  N NE2 . HIS B 2 552 ? 211.012 127.679 86.001  1.00 401.29 ? 574 HIS B NE2 1 
ATOM   5777  N N   . THR B 2 553 ? 215.984 129.662 90.050  1.00 392.51 ? 575 THR B N   1 
ATOM   5778  C CA  . THR B 2 553 ? 217.046 130.456 90.651  1.00 392.51 ? 575 THR B CA  1 
ATOM   5779  C C   . THR B 2 553 ? 218.018 131.018 89.624  1.00 392.51 ? 575 THR B C   1 
ATOM   5780  O O   . THR B 2 553 ? 218.933 131.759 89.998  1.00 392.51 ? 575 THR B O   1 
ATOM   5781  C CB  . THR B 2 553 ? 217.812 129.624 91.688  1.00 392.51 ? 575 THR B CB  1 
ATOM   5782  O OG1 . THR B 2 553 ? 218.932 130.375 92.174  1.00 392.51 ? 575 THR B OG1 1 
ATOM   5783  C CG2 . THR B 2 553 ? 218.304 128.324 91.073  1.00 392.51 ? 575 THR B CG2 1 
ATOM   5784  N N   . GLU B 2 554 ? 217.849 130.688 88.346  1.00 386.62 ? 576 GLU B N   1 
ATOM   5785  C CA  . GLU B 2 554 ? 218.670 131.232 87.276  1.00 386.62 ? 576 GLU B CA  1 
ATOM   5786  C C   . GLU B 2 554 ? 217.770 131.814 86.196  1.00 386.62 ? 576 GLU B C   1 
ATOM   5787  O O   . GLU B 2 554 ? 216.569 131.536 86.141  1.00 386.62 ? 576 GLU B O   1 
ATOM   5788  C CB  . GLU B 2 554 ? 219.597 130.168 86.668  1.00 386.62 ? 576 GLU B CB  1 
ATOM   5789  C CG  . GLU B 2 554 ? 220.409 129.383 87.685  1.00 386.62 ? 576 GLU B CG  1 
ATOM   5790  C CD  . GLU B 2 554 ? 219.811 128.023 87.982  1.00 386.62 ? 576 GLU B CD  1 
ATOM   5791  O OE1 . GLU B 2 554 ? 218.658 127.776 87.570  1.00 386.62 ? 576 GLU B OE1 1 
ATOM   5792  O OE2 . GLU B 2 554 ? 220.494 127.200 88.628  1.00 386.62 ? 576 GLU B OE2 1 
ATOM   5793  N N   . TYR B 2 555 ? 218.367 132.633 85.333  1.00 373.54 ? 577 TYR B N   1 
ATOM   5794  C CA  . TYR B 2 555 ? 217.635 133.250 84.237  1.00 373.54 ? 577 TYR B CA  1 
ATOM   5795  C C   . TYR B 2 555 ? 218.614 133.629 83.136  1.00 373.54 ? 577 TYR B C   1 
ATOM   5796  O O   . TYR B 2 555 ? 219.824 133.723 83.357  1.00 373.54 ? 577 TYR B O   1 
ATOM   5797  C CB  . TYR B 2 555 ? 216.846 134.479 84.705  1.00 373.54 ? 577 TYR B CB  1 
ATOM   5798  C CG  . TYR B 2 555 ? 215.646 134.794 83.842  1.00 373.54 ? 577 TYR B CG  1 
ATOM   5799  C CD1 . TYR B 2 555 ? 215.632 135.912 83.019  1.00 373.54 ? 577 TYR B CD1 1 
ATOM   5800  C CD2 . TYR B 2 555 ? 214.530 133.969 83.845  1.00 373.54 ? 577 TYR B CD2 1 
ATOM   5801  C CE1 . TYR B 2 555 ? 214.538 136.202 82.226  1.00 373.54 ? 577 TYR B CE1 1 
ATOM   5802  C CE2 . TYR B 2 555 ? 213.431 134.251 83.056  1.00 373.54 ? 577 TYR B CE2 1 
ATOM   5803  C CZ  . TYR B 2 555 ? 213.440 135.368 82.249  1.00 373.54 ? 577 TYR B CZ  1 
ATOM   5804  O OH  . TYR B 2 555 ? 212.347 135.651 81.462  1.00 373.54 ? 577 TYR B OH  1 
ATOM   5805  N N   . THR B 2 556 ? 218.071 133.843 81.939  1.00 364.12 ? 578 THR B N   1 
ATOM   5806  C CA  . THR B 2 556 ? 218.864 134.192 80.770  1.00 364.12 ? 578 THR B CA  1 
ATOM   5807  C C   . THR B 2 556 ? 218.360 135.497 80.172  1.00 364.12 ? 578 THR B C   1 
ATOM   5808  O O   . THR B 2 556 ? 217.180 135.839 80.286  1.00 364.12 ? 578 THR B O   1 
ATOM   5809  C CB  . THR B 2 556 ? 218.824 133.080 79.708  1.00 364.12 ? 578 THR B CB  1 
ATOM   5810  O OG1 . THR B 2 556 ? 219.625 133.462 78.582  1.00 364.12 ? 578 THR B OG1 1 
ATOM   5811  C CG2 . THR B 2 556 ? 217.396 132.824 79.250  1.00 364.12 ? 578 THR B CG2 1 
ATOM   5812  N N   . LEU B 2 557 ? 219.272 136.228 79.536  1.00 371.80 ? 579 LEU B N   1 
ATOM   5813  C CA  . LEU B 2 557 ? 218.962 137.490 78.879  1.00 371.80 ? 579 LEU B CA  1 
ATOM   5814  C C   . LEU B 2 557 ? 219.206 137.354 77.384  1.00 371.80 ? 579 LEU B C   1 
ATOM   5815  O O   . LEU B 2 557 ? 220.293 136.944 76.962  1.00 371.80 ? 579 LEU B O   1 
ATOM   5816  C CB  . LEU B 2 557 ? 219.803 138.635 79.451  1.00 371.80 ? 579 LEU B CB  1 
ATOM   5817  C CG  . LEU B 2 557 ? 219.999 138.652 80.968  1.00 371.80 ? 579 LEU B CG  1 
ATOM   5818  C CD1 . LEU B 2 557 ? 221.004 139.720 81.366  1.00 371.80 ? 579 LEU B CD1 1 
ATOM   5819  C CD2 . LEU B 2 557 ? 218.667 138.880 81.666  1.00 371.80 ? 579 LEU B CD2 1 
ATOM   5820  N N   . SER B 2 558 ? 218.198 137.698 76.590  1.00 415.69 ? 580 SER B N   1 
ATOM   5821  C CA  . SER B 2 558 ? 218.279 137.657 75.139  1.00 415.69 ? 580 SER B CA  1 
ATOM   5822  C C   . SER B 2 558 ? 218.298 139.072 74.575  1.00 415.69 ? 580 SER B C   1 
ATOM   5823  O O   . SER B 2 558 ? 218.033 140.052 75.277  1.00 415.69 ? 580 SER B O   1 
ATOM   5824  C CB  . SER B 2 558 ? 217.108 136.861 74.551  1.00 415.69 ? 580 SER B CB  1 
ATOM   5825  O OG  . SER B 2 558 ? 216.898 135.657 75.268  1.00 415.69 ? 580 SER B OG  1 
ATOM   5826  N N   . SER B 2 559 ? 218.620 139.162 73.282  1.00 431.27 ? 581 SER B N   1 
ATOM   5827  C CA  . SER B 2 559 ? 218.682 140.437 72.564  1.00 431.27 ? 581 SER B CA  1 
ATOM   5828  C C   . SER B 2 559 ? 219.652 141.408 73.235  1.00 431.27 ? 581 SER B C   1 
ATOM   5829  O O   . SER B 2 559 ? 219.350 142.589 73.421  1.00 431.27 ? 581 SER B O   1 
ATOM   5830  C CB  . SER B 2 559 ? 217.292 141.064 72.425  1.00 431.27 ? 581 SER B CB  1 
ATOM   5831  O OG  . SER B 2 559 ? 216.973 141.853 73.558  1.00 431.27 ? 581 SER B OG  1 
ATOM   5832  N N   . LEU B 2 560 ? 220.828 140.906 73.603  1.00 402.60 ? 582 LEU B N   1 
ATOM   5833  C CA  . LEU B 2 560 ? 221.849 141.720 74.246  1.00 402.60 ? 582 LEU B CA  1 
ATOM   5834  C C   . LEU B 2 560 ? 222.834 142.247 73.212  1.00 402.60 ? 582 LEU B C   1 
ATOM   5835  O O   . LEU B 2 560 ? 223.203 141.540 72.269  1.00 402.60 ? 582 LEU B O   1 
ATOM   5836  C CB  . LEU B 2 560 ? 222.591 140.913 75.312  1.00 402.60 ? 582 LEU B CB  1 
ATOM   5837  C CG  . LEU B 2 560 ? 221.960 140.880 76.706  1.00 402.60 ? 582 LEU B CG  1 
ATOM   5838  C CD1 . LEU B 2 560 ? 222.774 140.000 77.642  1.00 402.60 ? 582 LEU B CD1 1 
ATOM   5839  C CD2 . LEU B 2 560 ? 221.826 142.287 77.268  1.00 402.60 ? 582 LEU B CD2 1 
ATOM   5840  N N   . THR B 2 561 ? 223.258 143.492 73.396  1.00 392.06 ? 583 THR B N   1 
ATOM   5841  C CA  . THR B 2 561 ? 224.210 144.135 72.504  1.00 392.06 ? 583 THR B CA  1 
ATOM   5842  C C   . THR B 2 561 ? 225.627 143.984 73.045  1.00 392.06 ? 583 THR B C   1 
ATOM   5843  O O   . THR B 2 561 ? 225.838 143.804 74.247  1.00 392.06 ? 583 THR B O   1 
ATOM   5844  C CB  . THR B 2 561 ? 223.879 145.619 72.323  1.00 392.06 ? 583 THR B CB  1 
ATOM   5845  O OG1 . THR B 2 561 ? 224.897 146.246 71.534  1.00 392.06 ? 583 THR B OG1 1 
ATOM   5846  C CG2 . THR B 2 561 ? 223.788 146.316 73.673  1.00 392.06 ? 583 THR B CG2 1 
ATOM   5847  N N   . SER B 2 562 ? 226.597 144.057 72.141  1.00 386.07 ? 584 SER B N   1 
ATOM   5848  C CA  . SER B 2 562 ? 227.999 143.921 72.501  1.00 386.07 ? 584 SER B CA  1 
ATOM   5849  C C   . SER B 2 562 ? 228.637 145.291 72.708  1.00 386.07 ? 584 SER B C   1 
ATOM   5850  O O   . SER B 2 562 ? 228.147 146.314 72.222  1.00 386.07 ? 584 SER B O   1 
ATOM   5851  C CB  . SER B 2 562 ? 228.759 143.144 71.425  1.00 386.07 ? 584 SER B CB  1 
ATOM   5852  O OG  . SER B 2 562 ? 228.409 143.595 70.128  1.00 386.07 ? 584 SER B OG  1 
ATOM   5853  N N   . ASP B 2 563 ? 229.751 145.293 73.445  1.00 379.60 ? 585 ASP B N   1 
ATOM   5854  C CA  . ASP B 2 563 ? 230.512 146.508 73.740  1.00 379.60 ? 585 ASP B CA  1 
ATOM   5855  C C   . ASP B 2 563 ? 229.637 147.554 74.431  1.00 379.60 ? 585 ASP B C   1 
ATOM   5856  O O   . ASP B 2 563 ? 229.629 148.732 74.069  1.00 379.60 ? 585 ASP B O   1 
ATOM   5857  C CB  . ASP B 2 563 ? 231.153 147.078 72.471  1.00 379.60 ? 585 ASP B CB  1 
ATOM   5858  C CG  . ASP B 2 563 ? 232.024 146.065 71.755  1.00 379.60 ? 585 ASP B CG  1 
ATOM   5859  O OD1 . ASP B 2 563 ? 232.583 145.177 72.431  1.00 379.60 ? 585 ASP B OD1 1 
ATOM   5860  O OD2 . ASP B 2 563 ? 232.150 146.158 70.516  1.00 379.60 ? 585 ASP B OD2 1 
ATOM   5861  N N   . THR B 2 564 ? 228.893 147.109 75.440  1.00 398.33 ? 586 THR B N   1 
ATOM   5862  C CA  . THR B 2 564 ? 228.006 147.986 76.190  1.00 398.33 ? 586 THR B CA  1 
ATOM   5863  C C   . THR B 2 564 ? 227.966 147.528 77.640  1.00 398.33 ? 586 THR B C   1 
ATOM   5864  O O   . THR B 2 564 ? 227.917 146.327 77.917  1.00 398.33 ? 586 THR B O   1 
ATOM   5865  C CB  . THR B 2 564 ? 226.589 147.996 75.603  1.00 398.33 ? 586 THR B CB  1 
ATOM   5866  O OG1 . THR B 2 564 ? 226.658 148.061 74.173  1.00 398.33 ? 586 THR B OG1 1 
ATOM   5867  C CG2 . THR B 2 564 ? 225.806 149.194 76.119  1.00 398.33 ? 586 THR B CG2 1 
ATOM   5868  N N   . LEU B 2 565 ? 227.989 148.491 78.558  1.00 410.65 ? 587 LEU B N   1 
ATOM   5869  C CA  . LEU B 2 565 ? 227.933 148.205 79.984  1.00 410.65 ? 587 LEU B CA  1 
ATOM   5870  C C   . LEU B 2 565 ? 226.481 148.146 80.440  1.00 410.65 ? 587 LEU B C   1 
ATOM   5871  O O   . LEU B 2 565 ? 225.698 149.060 80.160  1.00 410.65 ? 587 LEU B O   1 
ATOM   5872  C CB  . LEU B 2 565 ? 228.697 149.265 80.778  1.00 410.65 ? 587 LEU B CB  1 
ATOM   5873  C CG  . LEU B 2 565 ? 228.964 148.949 82.251  1.00 410.65 ? 587 LEU B CG  1 
ATOM   5874  C CD1 . LEU B 2 565 ? 229.896 147.754 82.382  1.00 410.65 ? 587 LEU B CD1 1 
ATOM   5875  C CD2 . LEU B 2 565 ? 229.537 150.161 82.967  1.00 410.65 ? 587 LEU B CD2 1 
ATOM   5876  N N   . TYR B 2 566 ? 226.126 147.071 81.139  1.00 436.04 ? 588 TYR B N   1 
ATOM   5877  C CA  . TYR B 2 566 ? 224.768 146.852 81.614  1.00 436.04 ? 588 TYR B CA  1 
ATOM   5878  C C   . TYR B 2 566 ? 224.754 146.783 83.134  1.00 436.04 ? 588 TYR B C   1 
ATOM   5879  O O   . TYR B 2 566 ? 225.654 146.201 83.748  1.00 436.04 ? 588 TYR B O   1 
ATOM   5880  C CB  . TYR B 2 566 ? 224.178 145.563 81.029  1.00 436.04 ? 588 TYR B CB  1 
ATOM   5881  C CG  . TYR B 2 566 ? 223.444 145.760 79.721  1.00 436.04 ? 588 TYR B CG  1 
ATOM   5882  C CD1 . TYR B 2 566 ? 222.073 145.976 79.698  1.00 436.04 ? 588 TYR B CD1 1 
ATOM   5883  C CD2 . TYR B 2 566 ? 224.122 145.726 78.510  1.00 436.04 ? 588 TYR B CD2 1 
ATOM   5884  C CE1 . TYR B 2 566 ? 221.397 146.156 78.506  1.00 436.04 ? 588 TYR B CE1 1 
ATOM   5885  C CE2 . TYR B 2 566 ? 223.455 145.904 77.312  1.00 436.04 ? 588 TYR B CE2 1 
ATOM   5886  C CZ  . TYR B 2 566 ? 222.093 146.118 77.316  1.00 436.04 ? 588 TYR B CZ  1 
ATOM   5887  O OH  . TYR B 2 566 ? 221.425 146.296 76.126  1.00 436.04 ? 588 TYR B OH  1 
ATOM   5888  N N   . MET B 2 567 ? 223.727 147.378 83.735  1.00 447.72 ? 589 MET B N   1 
ATOM   5889  C CA  . MET B 2 567 ? 223.523 147.352 85.177  1.00 447.72 ? 589 MET B CA  1 
ATOM   5890  C C   . MET B 2 567 ? 222.216 146.633 85.475  1.00 447.72 ? 589 MET B C   1 
ATOM   5891  O O   . MET B 2 567 ? 221.168 146.992 84.929  1.00 447.72 ? 589 MET B O   1 
ATOM   5892  C CB  . MET B 2 567 ? 223.499 148.768 85.759  1.00 447.72 ? 589 MET B CB  1 
ATOM   5893  C CG  . MET B 2 567 ? 224.781 149.554 85.534  1.00 447.72 ? 589 MET B CG  1 
ATOM   5894  S SD  . MET B 2 567 ? 224.735 151.194 86.282  1.00 447.72 ? 589 MET B SD  1 
ATOM   5895  C CE  . MET B 2 567 ? 223.324 151.910 85.443  1.00 447.72 ? 589 MET B CE  1 
ATOM   5896  N N   . VAL B 2 568 ? 222.281 145.621 86.338  1.00 451.90 ? 590 VAL B N   1 
ATOM   5897  C CA  . VAL B 2 568 ? 221.124 144.796 86.656  1.00 451.90 ? 590 VAL B CA  1 
ATOM   5898  C C   . VAL B 2 568 ? 220.756 144.988 88.121  1.00 451.90 ? 590 VAL B C   1 
ATOM   5899  O O   . VAL B 2 568 ? 221.572 145.400 88.950  1.00 451.90 ? 590 VAL B O   1 
ATOM   5900  C CB  . VAL B 2 568 ? 221.372 143.304 86.349  1.00 451.90 ? 590 VAL B CB  1 
ATOM   5901  C CG1 . VAL B 2 568 ? 221.823 143.126 84.908  1.00 451.90 ? 590 VAL B CG1 1 
ATOM   5902  C CG2 . VAL B 2 568 ? 222.399 142.725 87.310  1.00 451.90 ? 590 VAL B CG2 1 
ATOM   5903  N N   . ARG B 2 569 ? 219.497 144.684 88.430  1.00 408.61 ? 591 ARG B N   1 
ATOM   5904  C CA  . ARG B 2 569 ? 218.991 144.743 89.793  1.00 408.61 ? 591 ARG B CA  1 
ATOM   5905  C C   . ARG B 2 569 ? 217.837 143.762 89.923  1.00 408.61 ? 591 ARG B C   1 
ATOM   5906  O O   . ARG B 2 569 ? 217.073 143.552 88.977  1.00 408.61 ? 591 ARG B O   1 
ATOM   5907  C CB  . ARG B 2 569 ? 218.538 146.158 90.172  1.00 408.61 ? 591 ARG B CB  1 
ATOM   5908  C CG  . ARG B 2 569 ? 218.455 146.400 91.671  1.00 408.61 ? 591 ARG B CG  1 
ATOM   5909  C CD  . ARG B 2 569 ? 218.260 147.874 91.986  1.00 408.61 ? 591 ARG B CD  1 
ATOM   5910  N NE  . ARG B 2 569 ? 218.458 148.160 93.404  1.00 408.61 ? 591 ARG B NE  1 
ATOM   5911  C CZ  . ARG B 2 569 ? 218.500 149.383 93.921  1.00 408.61 ? 591 ARG B CZ  1 
ATOM   5912  N NH1 . ARG B 2 569 ? 218.358 150.443 93.137  1.00 408.61 ? 591 ARG B NH1 1 
ATOM   5913  N NH2 . ARG B 2 569 ? 218.685 149.548 95.224  1.00 408.61 ? 591 ARG B NH2 1 
ATOM   5914  N N   . MET B 2 570 ? 217.715 143.162 91.106  1.00 388.79 ? 592 MET B N   1 
ATOM   5915  C CA  . MET B 2 570 ? 216.703 142.144 91.354  1.00 388.79 ? 592 MET B CA  1 
ATOM   5916  C C   . MET B 2 570 ? 215.991 142.445 92.663  1.00 388.79 ? 592 MET B C   1 
ATOM   5917  O O   . MET B 2 570 ? 216.637 142.772 93.663  1.00 388.79 ? 592 MET B O   1 
ATOM   5918  C CB  . MET B 2 570 ? 217.328 140.745 91.399  1.00 388.79 ? 592 MET B CB  1 
ATOM   5919  C CG  . MET B 2 570 ? 216.338 139.626 91.667  1.00 388.79 ? 592 MET B CG  1 
ATOM   5920  S SD  . MET B 2 570 ? 217.121 138.004 91.692  1.00 388.79 ? 592 MET B SD  1 
ATOM   5921  C CE  . MET B 2 570 ? 215.743 136.976 92.189  1.00 388.79 ? 592 MET B CE  1 
ATOM   5922  N N   . ALA B 2 571 ? 214.666 142.332 92.652  1.00 366.79 ? 593 ALA B N   1 
ATOM   5923  C CA  . ALA B 2 571 ? 213.843 142.570 93.827  1.00 366.79 ? 593 ALA B CA  1 
ATOM   5924  C C   . ALA B 2 571 ? 212.990 141.344 94.123  1.00 366.79 ? 593 ALA B C   1 
ATOM   5925  O O   . ALA B 2 571 ? 212.624 140.588 93.218  1.00 366.79 ? 593 ALA B O   1 
ATOM   5926  C CB  . ALA B 2 571 ? 212.943 143.797 93.638  1.00 366.79 ? 593 ALA B CB  1 
ATOM   5927  N N   . ALA B 2 572 ? 212.678 141.155 95.402  1.00 354.38 ? 594 ALA B N   1 
ATOM   5928  C CA  . ALA B 2 572 ? 211.835 140.060 95.863  1.00 354.38 ? 594 ALA B CA  1 
ATOM   5929  C C   . ALA B 2 572 ? 210.509 140.635 96.338  1.00 354.38 ? 594 ALA B C   1 
ATOM   5930  O O   . ALA B 2 572 ? 210.473 141.401 97.307  1.00 354.38 ? 594 ALA B O   1 
ATOM   5931  C CB  . ALA B 2 572 ? 212.518 139.275 96.982  1.00 354.38 ? 594 ALA B CB  1 
ATOM   5932  N N   . TYR B 2 573 ? 209.426 140.266 95.661  1.00 352.43 ? 595 TYR B N   1 
ATOM   5933  C CA  . TYR B 2 573 ? 208.105 140.800 95.953  1.00 352.43 ? 595 TYR B CA  1 
ATOM   5934  C C   . TYR B 2 573 ? 207.307 139.832 96.818  1.00 352.43 ? 595 TYR B C   1 
ATOM   5935  O O   . TYR B 2 573 ? 207.499 138.614 96.767  1.00 352.43 ? 595 TYR B O   1 
ATOM   5936  C CB  . TYR B 2 573 ? 207.340 141.094 94.660  1.00 352.43 ? 595 TYR B CB  1 
ATOM   5937  C CG  . TYR B 2 573 ? 207.604 142.471 94.095  1.00 352.43 ? 595 TYR B CG  1 
ATOM   5938  C CD1 . TYR B 2 573 ? 206.697 143.506 94.283  1.00 352.43 ? 595 TYR B CD1 1 
ATOM   5939  C CD2 . TYR B 2 573 ? 208.762 142.737 93.376  1.00 352.43 ? 595 TYR B CD2 1 
ATOM   5940  C CE1 . TYR B 2 573 ? 206.934 144.766 93.768  1.00 352.43 ? 595 TYR B CE1 1 
ATOM   5941  C CE2 . TYR B 2 573 ? 209.009 143.995 92.858  1.00 352.43 ? 595 TYR B CE2 1 
ATOM   5942  C CZ  . TYR B 2 573 ? 208.092 145.005 93.057  1.00 352.43 ? 595 TYR B CZ  1 
ATOM   5943  O OH  . TYR B 2 573 ? 208.333 146.258 92.543  1.00 352.43 ? 595 TYR B OH  1 
ATOM   5944  N N   . THR B 2 574 ? 206.404 140.397 97.619  1.00 351.65 ? 596 THR B N   1 
ATOM   5945  C CA  . THR B 2 574 ? 205.537 139.617 98.493  1.00 351.65 ? 596 THR B CA  1 
ATOM   5946  C C   . THR B 2 574 ? 204.109 140.123 98.298  1.00 351.65 ? 596 THR B C   1 
ATOM   5947  O O   . THR B 2 574 ? 203.877 140.999 97.458  1.00 351.65 ? 596 THR B O   1 
ATOM   5948  C CB  . THR B 2 574 ? 206.006 139.742 99.951  1.00 351.65 ? 596 THR B CB  1 
ATOM   5949  O OG1 . THR B 2 574 ? 207.428 139.583 100.000 1.00 351.65 ? 596 THR B OG1 1 
ATOM   5950  C CG2 . THR B 2 574 ? 205.397 138.649 100.828 1.00 351.65 ? 596 THR B CG2 1 
ATOM   5951  N N   . ASP B 2 575 ? 203.143 139.583 99.047  1.00 368.67 ? 597 ASP B N   1 
ATOM   5952  C CA  . ASP B 2 575 ? 201.762 140.032 98.905  1.00 368.67 ? 597 ASP B CA  1 
ATOM   5953  C C   . ASP B 2 575 ? 201.588 141.480 99.349  1.00 368.67 ? 597 ASP B C   1 
ATOM   5954  O O   . ASP B 2 575 ? 200.641 142.148 98.918  1.00 368.67 ? 597 ASP B O   1 
ATOM   5955  C CB  . ASP B 2 575 ? 200.829 139.118 99.699  1.00 368.67 ? 597 ASP B CB  1 
ATOM   5956  C CG  . ASP B 2 575 ? 200.937 137.667 99.274  1.00 368.67 ? 597 ASP B CG  1 
ATOM   5957  O OD1 . ASP B 2 575 ? 200.406 136.794 99.993  1.00 368.67 ? 597 ASP B OD1 1 
ATOM   5958  O OD2 . ASP B 2 575 ? 201.554 137.399 98.222  1.00 368.67 ? 597 ASP B OD2 1 
ATOM   5959  N N   . GLU B 2 576 ? 202.481 141.980 100.203 1.00 369.25 ? 598 GLU B N   1 
ATOM   5960  C CA  . GLU B 2 576 ? 202.418 143.366 100.650 1.00 369.25 ? 598 GLU B CA  1 
ATOM   5961  C C   . GLU B 2 576 ? 203.268 144.289 99.785  1.00 369.25 ? 598 GLU B C   1 
ATOM   5962  O O   . GLU B 2 576 ? 202.869 145.429 99.520  1.00 369.25 ? 598 GLU B O   1 
ATOM   5963  C CB  . GLU B 2 576 ? 202.861 143.468 102.113 1.00 369.25 ? 598 GLU B CB  1 
ATOM   5964  C CG  . GLU B 2 576 ? 202.718 144.857 102.718 1.00 369.25 ? 598 GLU B CG  1 
ATOM   5965  C CD  . GLU B 2 576 ? 201.308 145.405 102.601 1.00 369.25 ? 598 GLU B CD  1 
ATOM   5966  O OE1 . GLU B 2 576 ? 201.040 146.165 101.647 1.00 369.25 ? 598 GLU B OE1 1 
ATOM   5967  O OE2 . GLU B 2 576 ? 200.468 145.076 103.464 1.00 369.25 ? 598 GLU B OE2 1 
ATOM   5968  N N   . GLY B 2 577 ? 204.426 143.820 99.338  1.00 342.55 ? 599 GLY B N   1 
ATOM   5969  C CA  . GLY B 2 577 ? 205.290 144.636 98.512  1.00 342.55 ? 599 GLY B CA  1 
ATOM   5970  C C   . GLY B 2 577 ? 206.644 143.978 98.343  1.00 342.55 ? 599 GLY B C   1 
ATOM   5971  O O   . GLY B 2 577 ? 206.848 142.823 98.724  1.00 342.55 ? 599 GLY B O   1 
ATOM   5972  N N   . GLY B 2 578 ? 207.567 144.741 97.759  1.00 327.96 ? 600 GLY B N   1 
ATOM   5973  C CA  . GLY B 2 578 ? 208.908 144.253 97.525  1.00 327.96 ? 600 GLY B CA  1 
ATOM   5974  C C   . GLY B 2 578 ? 209.927 145.364 97.681  1.00 327.96 ? 600 GLY B C   1 
ATOM   5975  O O   . GLY B 2 578 ? 209.598 146.553 97.648  1.00 327.96 ? 600 GLY B O   1 
ATOM   5976  N N   . LYS B 2 579 ? 211.180 144.951 97.853  1.00 330.55 ? 601 LYS B N   1 
ATOM   5977  C CA  . LYS B 2 579 ? 212.298 145.869 98.015  1.00 330.55 ? 601 LYS B CA  1 
ATOM   5978  C C   . LYS B 2 579 ? 213.426 145.466 97.078  1.00 330.55 ? 601 LYS B C   1 
ATOM   5979  O O   . LYS B 2 579 ? 213.739 144.280 96.943  1.00 330.55 ? 601 LYS B O   1 
ATOM   5980  C CB  . LYS B 2 579 ? 212.801 145.888 99.465  1.00 330.55 ? 601 LYS B CB  1 
ATOM   5981  C CG  . LYS B 2 579 ? 211.774 146.379 100.473 1.00 330.55 ? 601 LYS B CG  1 
ATOM   5982  C CD  . LYS B 2 579 ? 211.360 147.813 100.186 1.00 330.55 ? 601 LYS B CD  1 
ATOM   5983  C CE  . LYS B 2 579 ? 210.325 148.299 101.187 1.00 330.55 ? 601 LYS B CE  1 
ATOM   5984  N NZ  . LYS B 2 579 ? 209.899 149.699 100.911 1.00 330.55 ? 601 LYS B NZ  1 
ATOM   5985  N N   . ASP B 2 580 ? 214.032 146.459 96.435  1.00 358.26 ? 602 ASP B N   1 
ATOM   5986  C CA  . ASP B 2 580 ? 215.117 146.205 95.500  1.00 358.26 ? 602 ASP B CA  1 
ATOM   5987  C C   . ASP B 2 580 ? 216.412 145.903 96.245  1.00 358.26 ? 602 ASP B C   1 
ATOM   5988  O O   . ASP B 2 580 ? 216.654 146.404 97.347  1.00 358.26 ? 602 ASP B O   1 
ATOM   5989  C CB  . ASP B 2 580 ? 215.316 147.403 94.571  1.00 358.26 ? 602 ASP B CB  1 
ATOM   5990  C CG  . ASP B 2 580 ? 214.057 147.761 93.805  1.00 358.26 ? 602 ASP B CG  1 
ATOM   5991  O OD1 . ASP B 2 580 ? 213.435 148.795 94.129  1.00 358.26 ? 602 ASP B OD1 1 
ATOM   5992  O OD2 . ASP B 2 580 ? 213.688 147.008 92.879  1.00 358.26 ? 602 ASP B OD2 1 
ATOM   5993  N N   . GLY B 2 581 ? 217.248 145.072 95.628  1.00 350.23 ? 603 GLY B N   1 
ATOM   5994  C CA  . GLY B 2 581 ? 218.501 144.672 96.220  1.00 350.23 ? 603 GLY B CA  1 
ATOM   5995  C C   . GLY B 2 581 ? 219.673 145.484 95.711  1.00 350.23 ? 603 GLY B C   1 
ATOM   5996  O O   . GLY B 2 581 ? 219.509 146.548 95.105  1.00 350.23 ? 603 GLY B O   1 
ATOM   5997  N N   . PRO B 2 582 ? 220.888 144.994 95.953  1.00 352.37 ? 604 PRO B N   1 
ATOM   5998  C CA  . PRO B 2 582 ? 222.077 145.721 95.494  1.00 352.37 ? 604 PRO B CA  1 
ATOM   5999  C C   . PRO B 2 582 ? 222.228 145.643 93.983  1.00 352.37 ? 604 PRO B C   1 
ATOM   6000  O O   . PRO B 2 582 ? 221.928 144.621 93.360  1.00 352.37 ? 604 PRO B O   1 
ATOM   6001  C CB  . PRO B 2 582 ? 223.228 145.006 96.210  1.00 352.37 ? 604 PRO B CB  1 
ATOM   6002  C CG  . PRO B 2 582 ? 222.715 143.623 96.440  1.00 352.37 ? 604 PRO B CG  1 
ATOM   6003  C CD  . PRO B 2 582 ? 221.235 143.759 96.676  1.00 352.37 ? 604 PRO B CD  1 
ATOM   6004  N N   . GLU B 2 583 ? 222.699 146.739 93.396  1.00 379.62 ? 605 GLU B N   1 
ATOM   6005  C CA  . GLU B 2 583 ? 222.892 146.806 91.955  1.00 379.62 ? 605 GLU B CA  1 
ATOM   6006  C C   . GLU B 2 583 ? 224.183 146.105 91.555  1.00 379.62 ? 605 GLU B C   1 
ATOM   6007  O O   . GLU B 2 583 ? 225.208 146.222 92.233  1.00 379.62 ? 605 GLU B O   1 
ATOM   6008  C CB  . GLU B 2 583 ? 222.921 148.260 91.486  1.00 379.62 ? 605 GLU B CB  1 
ATOM   6009  C CG  . GLU B 2 583 ? 221.715 149.078 91.917  1.00 379.62 ? 605 GLU B CG  1 
ATOM   6010  C CD  . GLU B 2 583 ? 221.712 150.471 91.319  1.00 379.62 ? 605 GLU B CD  1 
ATOM   6011  O OE1 . GLU B 2 583 ? 222.506 150.721 90.388  1.00 379.62 ? 605 GLU B OE1 1 
ATOM   6012  O OE2 . GLU B 2 583 ? 220.916 151.315 91.780  1.00 379.62 ? 605 GLU B OE2 1 
ATOM   6013  N N   . PHE B 2 584 ? 224.127 145.373 90.446  1.00 415.73 ? 606 PHE B N   1 
ATOM   6014  C CA  . PHE B 2 584 ? 225.281 144.679 89.899  1.00 415.73 ? 606 PHE B CA  1 
ATOM   6015  C C   . PHE B 2 584 ? 225.591 145.221 88.510  1.00 415.73 ? 606 PHE B C   1 
ATOM   6016  O O   . PHE B 2 584 ? 224.686 145.568 87.745  1.00 415.73 ? 606 PHE B O   1 
ATOM   6017  C CB  . PHE B 2 584 ? 225.041 143.165 89.831  1.00 415.73 ? 606 PHE B CB  1 
ATOM   6018  C CG  . PHE B 2 584 ? 226.290 142.362 89.596  1.00 415.73 ? 606 PHE B CG  1 
ATOM   6019  C CD1 . PHE B 2 584 ? 226.649 141.973 88.317  1.00 415.73 ? 606 PHE B CD1 1 
ATOM   6020  C CD2 . PHE B 2 584 ? 227.103 141.997 90.656  1.00 415.73 ? 606 PHE B CD2 1 
ATOM   6021  C CE1 . PHE B 2 584 ? 227.797 141.234 88.098  1.00 415.73 ? 606 PHE B CE1 1 
ATOM   6022  C CE2 . PHE B 2 584 ? 228.252 141.258 90.444  1.00 415.73 ? 606 PHE B CE2 1 
ATOM   6023  C CZ  . PHE B 2 584 ? 228.599 140.876 89.163  1.00 415.73 ? 606 PHE B CZ  1 
ATOM   6024  N N   . THR B 2 585 ? 226.882 145.291 88.191  1.00 412.91 ? 607 THR B N   1 
ATOM   6025  C CA  . THR B 2 585 ? 227.347 145.843 86.926  1.00 412.91 ? 607 THR B CA  1 
ATOM   6026  C C   . THR B 2 585 ? 228.253 144.834 86.238  1.00 412.91 ? 607 THR B C   1 
ATOM   6027  O O   . THR B 2 585 ? 229.146 144.263 86.871  1.00 412.91 ? 607 THR B O   1 
ATOM   6028  C CB  . THR B 2 585 ? 228.096 147.165 87.138  1.00 412.91 ? 607 THR B CB  1 
ATOM   6029  O OG1 . THR B 2 585 ? 227.348 148.003 88.028  1.00 412.91 ? 607 THR B OG1 1 
ATOM   6030  C CG2 . THR B 2 585 ? 228.288 147.887 85.813  1.00 412.91 ? 607 THR B CG2 1 
ATOM   6031  N N   . PHE B 2 586 ? 228.020 144.619 84.945  1.00 398.66 ? 608 PHE B N   1 
ATOM   6032  C CA  . PHE B 2 586 ? 228.839 143.711 84.157  1.00 398.66 ? 608 PHE B CA  1 
ATOM   6033  C C   . PHE B 2 586 ? 228.914 144.230 82.729  1.00 398.66 ? 608 PHE B C   1 
ATOM   6034  O O   . PHE B 2 586 ? 228.041 144.971 82.269  1.00 398.66 ? 608 PHE B O   1 
ATOM   6035  C CB  . PHE B 2 586 ? 228.286 142.280 84.186  1.00 398.66 ? 608 PHE B CB  1 
ATOM   6036  C CG  . PHE B 2 586 ? 227.082 142.073 83.309  1.00 398.66 ? 608 PHE B CG  1 
ATOM   6037  C CD1 . PHE B 2 586 ? 225.839 142.549 83.692  1.00 398.66 ? 608 PHE B CD1 1 
ATOM   6038  C CD2 . PHE B 2 586 ? 227.193 141.395 82.106  1.00 398.66 ? 608 PHE B CD2 1 
ATOM   6039  C CE1 . PHE B 2 586 ? 224.730 142.359 82.889  1.00 398.66 ? 608 PHE B CE1 1 
ATOM   6040  C CE2 . PHE B 2 586 ? 226.088 141.202 81.299  1.00 398.66 ? 608 PHE B CE2 1 
ATOM   6041  C CZ  . PHE B 2 586 ? 224.855 141.684 81.691  1.00 398.66 ? 608 PHE B CZ  1 
ATOM   6042  N N   . THR B 2 587 ? 229.972 143.831 82.031  1.00 381.00 ? 609 THR B N   1 
ATOM   6043  C CA  . THR B 2 587 ? 230.214 144.247 80.659  1.00 381.00 ? 609 THR B CA  1 
ATOM   6044  C C   . THR B 2 587 ? 229.990 143.081 79.705  1.00 381.00 ? 609 THR B C   1 
ATOM   6045  O O   . THR B 2 587 ? 229.971 141.913 80.104  1.00 381.00 ? 609 THR B O   1 
ATOM   6046  C CB  . THR B 2 587 ? 231.637 144.793 80.489  1.00 381.00 ? 609 THR B CB  1 
ATOM   6047  O OG1 . THR B 2 587 ? 231.786 145.347 79.176  1.00 381.00 ? 609 THR B OG1 1 
ATOM   6048  C CG2 . THR B 2 587 ? 232.662 143.686 80.687  1.00 381.00 ? 609 THR B CG2 1 
ATOM   6049  N N   . THR B 2 588 ? 229.815 143.416 78.428  1.00 371.64 ? 610 THR B N   1 
ATOM   6050  C CA  . THR B 2 588 ? 229.594 142.426 77.387  1.00 371.64 ? 610 THR B CA  1 
ATOM   6051  C C   . THR B 2 588 ? 230.836 142.296 76.521  1.00 371.64 ? 610 THR B C   1 
ATOM   6052  O O   . THR B 2 588 ? 231.330 143.307 76.003  1.00 371.64 ? 610 THR B O   1 
ATOM   6053  C CB  . THR B 2 588 ? 228.392 142.812 76.517  1.00 371.64 ? 610 THR B CB  1 
ATOM   6054  O OG1 . THR B 2 588 ? 227.327 143.283 77.352  1.00 371.64 ? 610 THR B OG1 1 
ATOM   6055  C CG2 . THR B 2 588 ? 227.907 141.613 75.716  1.00 371.64 ? 610 THR B CG2 1 
ATOM   6056  N N   . PRO B 2 589 ? 231.366 141.090 76.341  1.00 347.30 ? 611 PRO B N   1 
ATOM   6057  C CA  . PRO B 2 589 ? 232.564 140.927 75.511  1.00 347.30 ? 611 PRO B CA  1 
ATOM   6058  C C   . PRO B 2 589 ? 232.256 141.128 74.036  1.00 347.30 ? 611 PRO B C   1 
ATOM   6059  O O   . PRO B 2 589 ? 231.115 141.021 73.583  1.00 347.30 ? 611 PRO B O   1 
ATOM   6060  C CB  . PRO B 2 589 ? 233.000 139.486 75.796  1.00 347.30 ? 611 PRO B CB  1 
ATOM   6061  C CG  . PRO B 2 589 ? 231.740 138.791 76.190  1.00 347.30 ? 611 PRO B CG  1 
ATOM   6062  C CD  . PRO B 2 589 ? 230.912 139.813 76.919  1.00 347.30 ? 611 PRO B CD  1 
ATOM   6063  N N   . LYS B 2 590 ? 233.310 141.426 73.282  1.00 338.23 ? 612 LYS B N   1 
ATOM   6064  C CA  . LYS B 2 590 ? 233.189 141.651 71.847  1.00 338.23 ? 612 LYS B CA  1 
ATOM   6065  C C   . LYS B 2 590 ? 233.188 140.331 71.083  1.00 338.23 ? 612 LYS B C   1 
ATOM   6066  O O   . LYS B 2 590 ? 232.568 140.215 70.025  1.00 338.23 ? 612 LYS B O   1 
ATOM   6067  C CB  . LYS B 2 590 ? 234.324 142.547 71.348  1.00 338.23 ? 612 LYS B CB  1 
ATOM   6068  C CG  . LYS B 2 590 ? 235.714 142.000 71.627  1.00 338.23 ? 612 LYS B CG  1 
ATOM   6069  C CD  . LYS B 2 590 ? 236.788 143.016 71.273  1.00 338.23 ? 612 LYS B CD  1 
ATOM   6070  C CE  . LYS B 2 590 ? 236.627 144.292 72.083  1.00 338.23 ? 612 LYS B CE  1 
ATOM   6071  N NZ  . LYS B 2 590 ? 236.679 144.031 73.548  1.00 338.23 ? 612 LYS B NZ  1 
ATOM   6072  N N   . HIS C 3 7   ? 187.347 166.949 270.122 1.00 130.78 ? 51  HIS C N   1 
ATOM   6073  C CA  . HIS C 3 7   ? 188.800 166.836 270.070 1.00 130.78 ? 51  HIS C CA  1 
ATOM   6074  C C   . HIS C 3 7   ? 189.329 167.182 268.681 1.00 130.78 ? 51  HIS C C   1 
ATOM   6075  O O   . HIS C 3 7   ? 190.532 167.358 268.492 1.00 130.78 ? 51  HIS C O   1 
ATOM   6076  C CB  . HIS C 3 7   ? 189.243 165.426 270.465 1.00 130.78 ? 51  HIS C CB  1 
ATOM   6077  C CG  . HIS C 3 7   ? 188.918 165.065 271.881 1.00 130.78 ? 51  HIS C CG  1 
ATOM   6078  N ND1 . HIS C 3 7   ? 189.830 165.185 272.907 1.00 130.78 ? 51  HIS C ND1 1 
ATOM   6079  C CD2 . HIS C 3 7   ? 187.782 164.588 272.442 1.00 130.78 ? 51  HIS C CD2 1 
ATOM   6080  C CE1 . HIS C 3 7   ? 189.270 164.797 274.039 1.00 130.78 ? 51  HIS C CE1 1 
ATOM   6081  N NE2 . HIS C 3 7   ? 188.027 164.429 273.784 1.00 130.78 ? 51  HIS C NE2 1 
ATOM   6082  N N   . ASP C 3 8   ? 188.420 167.278 267.713 1.00 150.00 ? 52  ASP C N   1 
ATOM   6083  C CA  . ASP C 3 8   ? 188.761 167.600 266.330 1.00 150.00 ? 52  ASP C CA  1 
ATOM   6084  C C   . ASP C 3 8   ? 187.974 168.837 265.918 1.00 150.00 ? 52  ASP C C   1 
ATOM   6085  O O   . ASP C 3 8   ? 186.747 168.782 265.785 1.00 150.00 ? 52  ASP C O   1 
ATOM   6086  C CB  . ASP C 3 8   ? 188.460 166.423 265.404 1.00 150.00 ? 52  ASP C CB  1 
ATOM   6087  C CG  . ASP C 3 8   ? 189.281 165.194 265.740 1.00 150.00 ? 52  ASP C CG  1 
ATOM   6088  O OD1 . ASP C 3 8   ? 189.053 164.600 266.815 1.00 150.00 ? 52  ASP C OD1 1 
ATOM   6089  O OD2 . ASP C 3 8   ? 190.154 164.820 264.929 1.00 150.00 ? 52  ASP C OD2 1 
ATOM   6090  N N   . LEU C 3 9   ? 188.678 169.947 265.717 1.00 174.42 ? 53  LEU C N   1 
ATOM   6091  C CA  . LEU C 3 9   ? 188.068 171.217 265.343 1.00 174.42 ? 53  LEU C CA  1 
ATOM   6092  C C   . LEU C 3 9   ? 188.470 171.554 263.913 1.00 174.42 ? 53  LEU C C   1 
ATOM   6093  O O   . LEU C 3 9   ? 189.657 171.748 263.627 1.00 174.42 ? 53  LEU C O   1 
ATOM   6094  C CB  . LEU C 3 9   ? 188.494 172.330 266.300 1.00 174.42 ? 53  LEU C CB  1 
ATOM   6095  C CG  . LEU C 3 9   ? 188.055 173.760 265.970 1.00 174.42 ? 53  LEU C CG  1 
ATOM   6096  C CD1 . LEU C 3 9   ? 186.583 173.814 265.578 1.00 174.42 ? 53  LEU C CD1 1 
ATOM   6097  C CD2 . LEU C 3 9   ? 188.335 174.691 267.141 1.00 174.42 ? 53  LEU C CD2 1 
ATOM   6098  N N   . LYS C 3 10  ? 187.484 171.622 263.022 1.00 185.14 ? 54  LYS C N   1 
ATOM   6099  C CA  . LYS C 3 10  ? 187.695 171.988 261.627 1.00 185.14 ? 54  LYS C CA  1 
ATOM   6100  C C   . LYS C 3 10  ? 186.777 173.154 261.291 1.00 185.14 ? 54  LYS C C   1 
ATOM   6101  O O   . LYS C 3 10  ? 185.550 173.005 261.305 1.00 185.14 ? 54  LYS C O   1 
ATOM   6102  C CB  . LYS C 3 10  ? 187.428 170.802 260.698 1.00 185.14 ? 54  LYS C CB  1 
ATOM   6103  C CG  . LYS C 3 10  ? 188.290 169.583 260.986 1.00 185.14 ? 54  LYS C CG  1 
ATOM   6104  C CD  . LYS C 3 10  ? 189.769 169.910 260.861 1.00 185.14 ? 54  LYS C CD  1 
ATOM   6105  C CE  . LYS C 3 10  ? 190.632 168.713 261.222 1.00 185.14 ? 54  LYS C CE  1 
ATOM   6106  N NZ  . LYS C 3 10  ? 190.407 168.268 262.625 1.00 185.14 ? 54  LYS C NZ  1 
ATOM   6107  N N   . CYS C 3 11  ? 187.369 174.306 260.992 1.00 215.91 ? 55  CYS C N   1 
ATOM   6108  C CA  . CYS C 3 11  ? 186.625 175.525 260.712 1.00 215.91 ? 55  CYS C CA  1 
ATOM   6109  C C   . CYS C 3 11  ? 186.587 175.786 259.213 1.00 215.91 ? 55  CYS C C   1 
ATOM   6110  O O   . CYS C 3 11  ? 187.596 175.626 258.518 1.00 215.91 ? 55  CYS C O   1 
ATOM   6111  C CB  . CYS C 3 11  ? 187.242 176.725 261.435 1.00 215.91 ? 55  CYS C CB  1 
ATOM   6112  S SG  . CYS C 3 11  ? 186.127 178.137 261.607 1.00 215.91 ? 55  CYS C SG  1 
ATOM   6113  N N   . VAL C 3 12  ? 185.417 176.189 258.721 1.00 230.49 ? 56  VAL C N   1 
ATOM   6114  C CA  . VAL C 3 12  ? 185.220 176.500 257.313 1.00 230.49 ? 56  VAL C CA  1 
ATOM   6115  C C   . VAL C 3 12  ? 184.714 177.931 257.197 1.00 230.49 ? 56  VAL C C   1 
ATOM   6116  O O   . VAL C 3 12  ? 184.145 178.496 258.135 1.00 230.49 ? 56  VAL C O   1 
ATOM   6117  C CB  . VAL C 3 12  ? 184.244 175.520 256.630 1.00 230.49 ? 56  VAL C CB  1 
ATOM   6118  C CG1 . VAL C 3 12  ? 184.870 174.140 256.517 1.00 230.49 ? 56  VAL C CG1 1 
ATOM   6119  C CG2 . VAL C 3 12  ? 182.930 175.457 257.395 1.00 230.49 ? 56  VAL C CG2 1 
ATOM   6120  N N   . THR C 3 13  ? 184.931 178.519 256.022 1.00 223.07 ? 57  THR C N   1 
ATOM   6121  C CA  . THR C 3 13  ? 184.525 179.890 255.755 1.00 223.07 ? 57  THR C CA  1 
ATOM   6122  C C   . THR C 3 13  ? 184.102 180.016 254.300 1.00 223.07 ? 57  THR C C   1 
ATOM   6123  O O   . THR C 3 13  ? 184.741 179.450 253.408 1.00 223.07 ? 57  THR C O   1 
ATOM   6124  C CB  . THR C 3 13  ? 185.658 180.880 256.060 1.00 223.07 ? 57  THR C CB  1 
ATOM   6125  O OG1 . THR C 3 13  ? 186.177 180.625 257.371 1.00 223.07 ? 57  THR C OG1 1 
ATOM   6126  C CG2 . THR C 3 13  ? 185.151 182.312 255.994 1.00 223.07 ? 57  THR C CG2 1 
ATOM   6127  N N   . ASN C 3 14  ? 183.019 180.759 254.067 1.00 207.55 ? 58  ASN C N   1 
ATOM   6128  C CA  . ASN C 3 14  ? 182.496 180.972 252.726 1.00 207.55 ? 58  ASN C CA  1 
ATOM   6129  C C   . ASN C 3 14  ? 182.401 182.441 252.340 1.00 207.55 ? 58  ASN C C   1 
ATOM   6130  O O   . ASN C 3 14  ? 181.961 182.744 251.225 1.00 207.55 ? 58  ASN C O   1 
ATOM   6131  C CB  . ASN C 3 14  ? 181.114 180.318 252.585 1.00 207.55 ? 58  ASN C CB  1 
ATOM   6132  C CG  . ASN C 3 14  ? 180.124 180.817 253.620 1.00 207.55 ? 58  ASN C CG  1 
ATOM   6133  O OD1 . ASN C 3 14  ? 180.500 181.158 254.741 1.00 207.55 ? 58  ASN C OD1 1 
ATOM   6134  N ND2 . ASN C 3 14  ? 178.851 180.860 253.247 1.00 207.55 ? 58  ASN C ND2 1 
ATOM   6135  N N   . ASN C 3 15  ? 182.799 183.362 253.221 1.00 204.67 ? 59  ASN C N   1 
ATOM   6136  C CA  . ASN C 3 15  ? 182.711 184.783 252.918 1.00 204.67 ? 59  ASN C CA  1 
ATOM   6137  C C   . ASN C 3 15  ? 183.923 185.587 253.367 1.00 204.67 ? 59  ASN C C   1 
ATOM   6138  O O   . ASN C 3 15  ? 183.906 186.814 253.228 1.00 204.67 ? 59  ASN C O   1 
ATOM   6139  C CB  . ASN C 3 15  ? 181.445 185.386 253.552 1.00 204.67 ? 59  ASN C CB  1 
ATOM   6140  C CG  . ASN C 3 15  ? 181.270 184.983 255.004 1.00 204.67 ? 59  ASN C CG  1 
ATOM   6141  O OD1 . ASN C 3 15  ? 182.205 184.504 255.646 1.00 204.67 ? 59  ASN C OD1 1 
ATOM   6142  N ND2 . ASN C 3 15  ? 180.065 185.175 255.529 1.00 204.67 ? 59  ASN C ND2 1 
ATOM   6143  N N   . LEU C 3 16  ? 184.962 184.947 253.902 1.00 207.58 ? 60  LEU C N   1 
ATOM   6144  C CA  . LEU C 3 16  ? 186.178 185.593 254.392 1.00 207.58 ? 60  LEU C CA  1 
ATOM   6145  C C   . LEU C 3 16  ? 185.911 186.605 255.500 1.00 207.58 ? 60  LEU C C   1 
ATOM   6146  O O   . LEU C 3 16  ? 186.793 187.410 255.822 1.00 207.58 ? 60  LEU C O   1 
ATOM   6147  C CB  . LEU C 3 16  ? 186.955 186.269 253.253 1.00 207.58 ? 60  LEU C CB  1 
ATOM   6148  C CG  . LEU C 3 16  ? 187.511 185.345 252.170 1.00 207.58 ? 60  LEU C CG  1 
ATOM   6149  C CD1 . LEU C 3 16  ? 188.249 186.146 251.110 1.00 207.58 ? 60  LEU C CD1 1 
ATOM   6150  C CD2 . LEU C 3 16  ? 188.423 184.298 252.785 1.00 207.58 ? 60  LEU C CD2 1 
ATOM   6151  N N   . GLN C 3 17  ? 184.726 186.589 256.092 1.00 195.33 ? 61  GLN C N   1 
ATOM   6152  C CA  . GLN C 3 17  ? 184.383 187.510 257.170 1.00 195.33 ? 61  GLN C CA  1 
ATOM   6153  C C   . GLN C 3 17  ? 183.867 186.800 258.411 1.00 195.33 ? 61  GLN C C   1 
ATOM   6154  O O   . GLN C 3 17  ? 184.144 187.248 259.526 1.00 195.33 ? 61  GLN C O   1 
ATOM   6155  C CB  . GLN C 3 17  ? 183.340 188.532 256.684 1.00 195.33 ? 61  GLN C CB  1 
ATOM   6156  C CG  . GLN C 3 17  ? 183.724 189.261 255.404 1.00 195.33 ? 61  GLN C CG  1 
ATOM   6157  C CD  . GLN C 3 17  ? 185.019 190.041 255.538 1.00 195.33 ? 61  GLN C CD  1 
ATOM   6158  O OE1 . GLN C 3 17  ? 185.324 190.586 256.599 1.00 195.33 ? 61  GLN C OE1 1 
ATOM   6159  N NE2 . GLN C 3 17  ? 185.790 190.097 254.457 1.00 195.33 ? 61  GLN C NE2 1 
ATOM   6160  N N   . VAL C 3 18  ? 183.123 185.709 258.249 1.00 187.71 ? 62  VAL C N   1 
ATOM   6161  C CA  . VAL C 3 18  ? 182.580 184.942 259.365 1.00 187.71 ? 62  VAL C CA  1 
ATOM   6162  C C   . VAL C 3 18  ? 183.073 183.509 259.233 1.00 187.71 ? 62  VAL C C   1 
ATOM   6163  O O   . VAL C 3 18  ? 182.802 182.843 258.226 1.00 187.71 ? 62  VAL C O   1 
ATOM   6164  C CB  . VAL C 3 18  ? 181.045 184.992 259.402 1.00 187.71 ? 62  VAL C CB  1 
ATOM   6165  C CG1 . VAL C 3 18  ? 180.516 184.143 260.548 1.00 187.71 ? 62  VAL C CG1 1 
ATOM   6166  C CG2 . VAL C 3 18  ? 180.562 186.429 259.528 1.00 187.71 ? 62  VAL C CG2 1 
ATOM   6167  N N   . TRP C 3 19  ? 183.791 183.035 260.248 1.00 191.73 ? 63  TRP C N   1 
ATOM   6168  C CA  . TRP C 3 19  ? 184.334 181.683 260.254 1.00 191.73 ? 63  TRP C CA  1 
ATOM   6169  C C   . TRP C 3 19  ? 183.346 180.749 260.945 1.00 191.73 ? 63  TRP C C   1 
ATOM   6170  O O   . TRP C 3 19  ? 183.025 180.939 262.123 1.00 191.73 ? 63  TRP C O   1 
ATOM   6171  C CB  . TRP C 3 19  ? 185.689 181.645 260.959 1.00 191.73 ? 63  TRP C CB  1 
ATOM   6172  C CG  . TRP C 3 19  ? 186.772 182.405 260.252 1.00 191.73 ? 63  TRP C CG  1 
ATOM   6173  C CD1 . TRP C 3 19  ? 186.655 183.117 259.093 1.00 191.73 ? 63  TRP C CD1 1 
ATOM   6174  C CD2 . TRP C 3 19  ? 188.140 182.528 260.661 1.00 191.73 ? 63  TRP C CD2 1 
ATOM   6175  N NE1 . TRP C 3 19  ? 187.865 183.674 258.756 1.00 191.73 ? 63  TRP C NE1 1 
ATOM   6176  C CE2 . TRP C 3 19  ? 188.792 183.328 259.703 1.00 191.73 ? 63  TRP C CE2 1 
ATOM   6177  C CE3 . TRP C 3 19  ? 188.875 182.040 261.746 1.00 191.73 ? 63  TRP C CE3 1 
ATOM   6178  C CZ2 . TRP C 3 19  ? 190.145 183.650 259.795 1.00 191.73 ? 63  TRP C CZ2 1 
ATOM   6179  C CZ3 . TRP C 3 19  ? 190.217 182.361 261.836 1.00 191.73 ? 63  TRP C CZ3 1 
ATOM   6180  C CH2 . TRP C 3 19  ? 190.838 183.158 260.867 1.00 191.73 ? 63  TRP C CH2 1 
ATOM   6181  N N   . ASN C 3 20  ? 182.868 179.745 260.213 1.00 202.74 ? 64  ASN C N   1 
ATOM   6182  C CA  . ASN C 3 20  ? 181.930 178.757 260.745 1.00 202.74 ? 64  ASN C CA  1 
ATOM   6183  C C   . ASN C 3 20  ? 182.741 177.555 261.217 1.00 202.74 ? 64  ASN C C   1 
ATOM   6184  O O   . ASN C 3 20  ? 183.001 176.619 260.460 1.00 202.74 ? 64  ASN C O   1 
ATOM   6185  C CB  . ASN C 3 20  ? 180.896 178.366 259.696 1.00 202.74 ? 64  ASN C CB  1 
ATOM   6186  C CG  . ASN C 3 20  ? 179.942 177.294 260.187 1.00 202.74 ? 64  ASN C CG  1 
ATOM   6187  O OD1 . ASN C 3 20  ? 179.702 177.162 261.387 1.00 202.74 ? 64  ASN C OD1 1 
ATOM   6188  N ND2 . ASN C 3 20  ? 179.393 176.520 259.258 1.00 202.74 ? 64  ASN C ND2 1 
ATOM   6189  N N   . CYS C 3 21  ? 183.142 177.584 262.485 1.00 190.47 ? 65  CYS C N   1 
ATOM   6190  C CA  . CYS C 3 21  ? 183.935 176.512 263.069 1.00 190.47 ? 65  CYS C CA  1 
ATOM   6191  C C   . CYS C 3 21  ? 183.018 175.442 263.646 1.00 190.47 ? 65  CYS C C   1 
ATOM   6192  O O   . CYS C 3 21  ? 182.081 175.751 264.389 1.00 190.47 ? 65  CYS C O   1 
ATOM   6193  C CB  . CYS C 3 21  ? 184.866 177.055 264.153 1.00 190.47 ? 65  CYS C CB  1 
ATOM   6194  S SG  . CYS C 3 21  ? 185.948 178.401 263.614 1.00 190.47 ? 65  CYS C SG  1 
ATOM   6195  N N   . SER C 3 22  ? 183.290 174.186 263.299 1.00 179.67 ? 66  SER C N   1 
ATOM   6196  C CA  . SER C 3 22  ? 182.520 173.049 263.779 1.00 179.67 ? 66  SER C CA  1 
ATOM   6197  C C   . SER C 3 22  ? 183.458 172.038 264.419 1.00 179.67 ? 66  SER C C   1 
ATOM   6198  O O   . SER C 3 22  ? 184.563 171.802 263.923 1.00 179.67 ? 66  SER C O   1 
ATOM   6199  C CB  . SER C 3 22  ? 181.732 172.388 262.641 1.00 179.67 ? 66  SER C CB  1 
ATOM   6200  O OG  . SER C 3 22  ? 182.573 172.108 261.535 1.00 179.67 ? 66  SER C OG  1 
ATOM   6201  N N   . TRP C 3 23  ? 183.010 171.441 265.522 1.00 178.09 ? 67  TRP C N   1 
ATOM   6202  C CA  . TRP C 3 23  ? 183.804 170.464 266.252 1.00 178.09 ? 67  TRP C CA  1 
ATOM   6203  C C   . TRP C 3 23  ? 182.930 169.268 266.598 1.00 178.09 ? 67  TRP C C   1 
ATOM   6204  O O   . TRP C 3 23  ? 181.709 169.286 266.418 1.00 178.09 ? 67  TRP C O   1 
ATOM   6205  C CB  . TRP C 3 23  ? 184.418 171.073 267.519 1.00 178.09 ? 67  TRP C CB  1 
ATOM   6206  C CG  . TRP C 3 23  ? 183.412 171.423 268.572 1.00 178.09 ? 67  TRP C CG  1 
ATOM   6207  C CD1 . TRP C 3 23  ? 183.112 170.701 269.690 1.00 178.09 ? 67  TRP C CD1 1 
ATOM   6208  C CD2 . TRP C 3 23  ? 182.575 172.585 268.608 1.00 178.09 ? 67  TRP C CD2 1 
ATOM   6209  N NE1 . TRP C 3 23  ? 182.140 171.340 270.420 1.00 178.09 ? 67  TRP C NE1 1 
ATOM   6210  C CE2 . TRP C 3 23  ? 181.793 172.499 269.777 1.00 178.09 ? 67  TRP C CE2 1 
ATOM   6211  C CE3 . TRP C 3 23  ? 182.411 173.689 267.766 1.00 178.09 ? 67  TRP C CE3 1 
ATOM   6212  C CZ2 . TRP C 3 23  ? 180.862 173.475 270.126 1.00 178.09 ? 67  TRP C CZ2 1 
ATOM   6213  C CZ3 . TRP C 3 23  ? 181.484 174.657 268.114 1.00 178.09 ? 67  TRP C CZ3 1 
ATOM   6214  C CH2 . TRP C 3 23  ? 180.722 174.543 269.282 1.00 178.09 ? 67  TRP C CH2 1 
ATOM   6215  N N   . LYS C 3 24  ? 183.572 168.217 267.098 1.00 167.79 ? 68  LYS C N   1 
ATOM   6216  C CA  . LYS C 3 24  ? 182.883 166.985 267.448 1.00 167.79 ? 68  LYS C CA  1 
ATOM   6217  C C   . LYS C 3 24  ? 182.491 166.984 268.920 1.00 167.79 ? 68  LYS C C   1 
ATOM   6218  O O   . LYS C 3 24  ? 183.144 167.608 269.760 1.00 167.79 ? 68  LYS C O   1 
ATOM   6219  C CB  . LYS C 3 24  ? 183.764 165.771 267.145 1.00 167.79 ? 68  LYS C CB  1 
ATOM   6220  C CG  . LYS C 3 24  ? 185.151 165.845 267.760 1.00 167.79 ? 68  LYS C CG  1 
ATOM   6221  C CD  . LYS C 3 24  ? 185.860 164.504 267.680 1.00 167.79 ? 68  LYS C CD  1 
ATOM   6222  C CE  . LYS C 3 24  ? 185.147 163.455 268.518 1.00 167.79 ? 68  LYS C CE  1 
ATOM   6223  N NZ  . LYS C 3 24  ? 185.065 163.854 269.951 1.00 167.79 ? 68  LYS C NZ  1 
ATOM   6224  N N   . ALA C 3 25  ? 181.409 166.269 269.224 1.00 182.61 ? 69  ALA C N   1 
ATOM   6225  C CA  . ALA C 3 25  ? 180.940 166.167 270.599 1.00 182.61 ? 69  ALA C CA  1 
ATOM   6226  C C   . ALA C 3 25  ? 181.779 165.148 271.369 1.00 182.61 ? 69  ALA C C   1 
ATOM   6227  O O   . ALA C 3 25  ? 182.177 164.122 270.810 1.00 182.61 ? 69  ALA C O   1 
ATOM   6228  C CB  . ALA C 3 25  ? 179.468 165.761 270.636 1.00 182.61 ? 69  ALA C CB  1 
ATOM   6229  N N   . PRO C 3 26  ? 182.066 165.408 272.642 1.00 199.12 ? 70  PRO C N   1 
ATOM   6230  C CA  . PRO C 3 26  ? 182.866 164.463 273.428 1.00 199.12 ? 70  PRO C CA  1 
ATOM   6231  C C   . PRO C 3 26  ? 182.136 163.146 273.641 1.00 199.12 ? 70  PRO C C   1 
ATOM   6232  O O   . PRO C 3 26  ? 180.919 163.037 273.477 1.00 199.12 ? 70  PRO C O   1 
ATOM   6233  C CB  . PRO C 3 26  ? 183.086 165.195 274.758 1.00 199.12 ? 70  PRO C CB  1 
ATOM   6234  C CG  . PRO C 3 26  ? 182.804 166.637 274.464 1.00 199.12 ? 70  PRO C CG  1 
ATOM   6235  C CD  . PRO C 3 26  ? 181.756 166.633 273.396 1.00 199.12 ? 70  PRO C CD  1 
ATOM   6236  N N   . SER C 3 27  ? 182.911 162.132 274.017 1.00 186.95 ? 71  SER C N   1 
ATOM   6237  C CA  . SER C 3 27  ? 182.359 160.806 274.263 1.00 186.95 ? 71  SER C CA  1 
ATOM   6238  C C   . SER C 3 27  ? 181.609 160.796 275.590 1.00 186.95 ? 71  SER C C   1 
ATOM   6239  O O   . SER C 3 27  ? 182.204 161.011 276.651 1.00 186.95 ? 71  SER C O   1 
ATOM   6240  C CB  . SER C 3 27  ? 183.472 159.762 274.265 1.00 186.95 ? 71  SER C CB  1 
ATOM   6241  O OG  . SER C 3 27  ? 183.073 158.592 274.958 1.00 186.95 ? 71  SER C OG  1 
ATOM   6242  N N   . GLY C 3 28  ? 180.303 160.546 275.530 1.00 218.59 ? 72  GLY C N   1 
ATOM   6243  C CA  . GLY C 3 28  ? 179.456 160.518 276.705 1.00 218.59 ? 72  GLY C CA  1 
ATOM   6244  C C   . GLY C 3 28  ? 178.471 161.662 276.796 1.00 218.59 ? 72  GLY C C   1 
ATOM   6245  O O   . GLY C 3 28  ? 177.594 161.632 277.669 1.00 218.59 ? 72  GLY C O   1 
ATOM   6246  N N   . THR C 3 29  ? 178.583 162.665 275.929 1.00 252.19 ? 73  THR C N   1 
ATOM   6247  C CA  . THR C 3 29  ? 177.671 163.801 275.950 1.00 252.19 ? 73  THR C CA  1 
ATOM   6248  C C   . THR C 3 29  ? 176.402 163.451 275.181 1.00 252.19 ? 73  THR C C   1 
ATOM   6249  O O   . THR C 3 29  ? 176.462 163.100 273.998 1.00 252.19 ? 73  THR C O   1 
ATOM   6250  C CB  . THR C 3 29  ? 178.341 165.035 275.349 1.00 252.19 ? 73  THR C CB  1 
ATOM   6251  O OG1 . THR C 3 29  ? 178.657 164.788 273.973 1.00 252.19 ? 73  THR C OG1 1 
ATOM   6252  C CG2 . THR C 3 29  ? 179.620 165.362 276.105 1.00 252.19 ? 73  THR C CG2 1 
ATOM   6253  N N   . GLY C 3 30  ? 175.256 163.545 275.853 1.00 307.70 ? 74  GLY C N   1 
ATOM   6254  C CA  . GLY C 3 30  ? 173.979 163.236 275.250 1.00 307.70 ? 74  GLY C CA  1 
ATOM   6255  C C   . GLY C 3 30  ? 173.362 164.433 274.552 1.00 307.70 ? 74  GLY C C   1 
ATOM   6256  O O   . GLY C 3 30  ? 173.975 165.489 274.391 1.00 307.70 ? 74  GLY C O   1 
ATOM   6257  N N   . ARG C 3 31  ? 172.114 164.249 274.128 1.00 337.94 ? 75  ARG C N   1 
ATOM   6258  C CA  . ARG C 3 31  ? 171.385 165.315 273.457 1.00 337.94 ? 75  ARG C CA  1 
ATOM   6259  C C   . ARG C 3 31  ? 171.053 166.438 274.433 1.00 337.94 ? 75  ARG C C   1 
ATOM   6260  O O   . ARG C 3 31  ? 170.965 166.235 275.647 1.00 337.94 ? 75  ARG C O   1 
ATOM   6261  C CB  . ARG C 3 31  ? 170.102 164.774 272.822 1.00 337.94 ? 75  ARG C CB  1 
ATOM   6262  C CG  . ARG C 3 31  ? 168.979 164.467 273.808 1.00 337.94 ? 75  ARG C CG  1 
ATOM   6263  C CD  . ARG C 3 31  ? 169.165 163.111 274.474 1.00 337.94 ? 75  ARG C CD  1 
ATOM   6264  N NE  . ARG C 3 31  ? 167.984 162.704 275.230 1.00 337.94 ? 75  ARG C NE  1 
ATOM   6265  C CZ  . ARG C 3 31  ? 167.951 161.671 276.065 1.00 337.94 ? 75  ARG C CZ  1 
ATOM   6266  N NH1 . ARG C 3 31  ? 169.038 160.934 276.254 1.00 337.94 ? 75  ARG C NH1 1 
ATOM   6267  N NH2 . ARG C 3 31  ? 166.833 161.373 276.711 1.00 337.94 ? 75  ARG C NH2 1 
ATOM   6268  N N   . GLY C 3 32  ? 170.873 167.636 273.888 1.00 336.62 ? 76  GLY C N   1 
ATOM   6269  C CA  . GLY C 3 32  ? 170.583 168.798 274.710 1.00 336.62 ? 76  GLY C CA  1 
ATOM   6270  C C   . GLY C 3 32  ? 171.756 169.264 275.546 1.00 336.62 ? 76  GLY C C   1 
ATOM   6271  O O   . GLY C 3 32  ? 171.573 169.635 276.712 1.00 336.62 ? 76  GLY C O   1 
ATOM   6272  N N   . THR C 3 33  ? 172.959 169.255 274.977 1.00 310.15 ? 77  THR C N   1 
ATOM   6273  C CA  . THR C 3 33  ? 174.163 169.645 275.698 1.00 310.15 ? 77  THR C CA  1 
ATOM   6274  C C   . THR C 3 33  ? 174.482 171.110 275.428 1.00 310.15 ? 77  THR C C   1 
ATOM   6275  O O   . THR C 3 33  ? 174.545 171.535 274.270 1.00 310.15 ? 77  THR C O   1 
ATOM   6276  C CB  . THR C 3 33  ? 175.345 168.765 275.290 1.00 310.15 ? 77  THR C CB  1 
ATOM   6277  O OG1 . THR C 3 33  ? 175.108 167.415 275.710 1.00 310.15 ? 77  THR C OG1 1 
ATOM   6278  C CG2 . THR C 3 33  ? 176.631 169.270 275.924 1.00 310.15 ? 77  THR C CG2 1 
ATOM   6279  N N   . ASP C 3 34  ? 174.683 171.875 276.498 1.00 294.73 ? 78  ASP C N   1 
ATOM   6280  C CA  . ASP C 3 34  ? 175.047 173.279 276.388 1.00 294.73 ? 78  ASP C CA  1 
ATOM   6281  C C   . ASP C 3 34  ? 176.559 173.419 276.274 1.00 294.73 ? 78  ASP C C   1 
ATOM   6282  O O   . ASP C 3 34  ? 177.312 172.754 276.991 1.00 294.73 ? 78  ASP C O   1 
ATOM   6283  C CB  . ASP C 3 34  ? 174.536 174.066 277.596 1.00 294.73 ? 78  ASP C CB  1 
ATOM   6284  C CG  . ASP C 3 34  ? 173.048 173.886 277.822 1.00 294.73 ? 78  ASP C CG  1 
ATOM   6285  O OD1 . ASP C 3 34  ? 172.317 173.671 276.834 1.00 294.73 ? 78  ASP C OD1 1 
ATOM   6286  O OD2 . ASP C 3 34  ? 172.611 173.959 278.990 1.00 294.73 ? 78  ASP C OD2 1 
ATOM   6287  N N   . TYR C 3 35  ? 176.997 174.290 275.369 1.00 269.57 ? 79  TYR C N   1 
ATOM   6288  C CA  . TYR C 3 35  ? 178.412 174.524 275.121 1.00 269.57 ? 79  TYR C CA  1 
ATOM   6289  C C   . TYR C 3 35  ? 178.736 175.997 275.320 1.00 269.57 ? 79  TYR C C   1 
ATOM   6290  O O   . TYR C 3 35  ? 177.983 176.874 274.885 1.00 269.57 ? 79  TYR C O   1 
ATOM   6291  C CB  . TYR C 3 35  ? 178.807 174.093 273.704 1.00 269.57 ? 79  TYR C CB  1 
ATOM   6292  C CG  . TYR C 3 35  ? 178.651 172.613 273.440 1.00 269.57 ? 79  TYR C CG  1 
ATOM   6293  C CD1 . TYR C 3 35  ? 179.684 171.726 273.714 1.00 269.57 ? 79  TYR C CD1 1 
ATOM   6294  C CD2 . TYR C 3 35  ? 177.473 172.102 272.911 1.00 269.57 ? 79  TYR C CD2 1 
ATOM   6295  C CE1 . TYR C 3 35  ? 179.547 170.372 273.472 1.00 269.57 ? 79  TYR C CE1 1 
ATOM   6296  C CE2 . TYR C 3 35  ? 177.326 170.750 272.666 1.00 269.57 ? 79  TYR C CE2 1 
ATOM   6297  C CZ  . TYR C 3 35  ? 178.367 169.890 272.947 1.00 269.57 ? 79  TYR C CZ  1 
ATOM   6298  O OH  . TYR C 3 35  ? 178.225 168.543 272.705 1.00 269.57 ? 79  TYR C OH  1 
ATOM   6299  N N   . GLU C 3 36  ? 179.861 176.262 275.979 1.00 214.30 ? 80  GLU C N   1 
ATOM   6300  C CA  . GLU C 3 36  ? 180.365 177.616 276.199 1.00 214.30 ? 80  GLU C CA  1 
ATOM   6301  C C   . GLU C 3 36  ? 181.730 177.703 275.522 1.00 214.30 ? 80  GLU C C   1 
ATOM   6302  O O   . GLU C 3 36  ? 182.764 177.452 276.145 1.00 214.30 ? 80  GLU C O   1 
ATOM   6303  C CB  . GLU C 3 36  ? 180.449 177.944 277.689 1.00 214.30 ? 80  GLU C CB  1 
ATOM   6304  C CG  . GLU C 3 36  ? 180.871 179.374 277.986 1.00 214.30 ? 80  GLU C CG  1 
ATOM   6305  C CD  . GLU C 3 36  ? 180.980 179.653 279.472 1.00 214.30 ? 80  GLU C CD  1 
ATOM   6306  O OE1 . GLU C 3 36  ? 180.569 178.787 280.272 1.00 214.30 ? 80  GLU C OE1 1 
ATOM   6307  O OE2 . GLU C 3 36  ? 181.477 180.738 279.839 1.00 214.30 ? 80  GLU C OE2 1 
ATOM   6308  N N   . VAL C 3 37  ? 181.727 178.058 274.240 1.00 224.95 ? 81  VAL C N   1 
ATOM   6309  C CA  . VAL C 3 37  ? 182.936 178.123 273.429 1.00 224.95 ? 81  VAL C CA  1 
ATOM   6310  C C   . VAL C 3 37  ? 183.181 179.570 273.029 1.00 224.95 ? 81  VAL C C   1 
ATOM   6311  O O   . VAL C 3 37  ? 182.246 180.292 272.668 1.00 224.95 ? 81  VAL C O   1 
ATOM   6312  C CB  . VAL C 3 37  ? 182.830 177.223 272.179 1.00 224.95 ? 81  VAL C CB  1 
ATOM   6313  C CG1 . VAL C 3 37  ? 184.196 177.042 271.537 1.00 224.95 ? 81  VAL C CG1 1 
ATOM   6314  C CG2 . VAL C 3 37  ? 182.224 175.876 272.544 1.00 224.95 ? 81  VAL C CG2 1 
ATOM   6315  N N   . CYS C 3 38  ? 184.442 179.989 273.095 1.00 210.99 ? 82  CYS C N   1 
ATOM   6316  C CA  . CYS C 3 38  ? 184.831 181.339 272.711 1.00 210.99 ? 82  CYS C CA  1 
ATOM   6317  C C   . CYS C 3 38  ? 186.317 181.337 272.376 1.00 210.99 ? 82  CYS C C   1 
ATOM   6318  O O   . CYS C 3 38  ? 186.986 180.301 272.429 1.00 210.99 ? 82  CYS C O   1 
ATOM   6319  C CB  . CYS C 3 38  ? 184.498 182.348 273.814 1.00 210.99 ? 82  CYS C CB  1 
ATOM   6320  S SG  . CYS C 3 38  ? 185.011 181.864 275.478 1.00 210.99 ? 82  CYS C SG  1 
ATOM   6321  N N   . ILE C 3 39  ? 186.831 182.515 272.030 1.00 202.35 ? 83  ILE C N   1 
ATOM   6322  C CA  . ILE C 3 39  ? 188.204 182.682 271.574 1.00 202.35 ? 83  ILE C CA  1 
ATOM   6323  C C   . ILE C 3 39  ? 188.931 183.613 272.533 1.00 202.35 ? 83  ILE C C   1 
ATOM   6324  O O   . ILE C 3 39  ? 188.399 184.658 272.922 1.00 202.35 ? 83  ILE C O   1 
ATOM   6325  C CB  . ILE C 3 39  ? 188.260 183.235 270.134 1.00 202.35 ? 83  ILE C CB  1 
ATOM   6326  C CG1 . ILE C 3 39  ? 187.518 182.305 269.173 1.00 202.35 ? 83  ILE C CG1 1 
ATOM   6327  C CG2 . ILE C 3 39  ? 189.699 183.428 269.687 1.00 202.35 ? 83  ILE C CG2 1 
ATOM   6328  C CD1 . ILE C 3 39  ? 186.118 182.768 268.840 1.00 202.35 ? 83  ILE C CD1 1 
ATOM   6329  N N   . GLU C 3 40  ? 190.149 183.231 272.911 1.00 205.54 ? 84  GLU C N   1 
ATOM   6330  C CA  . GLU C 3 40  ? 190.999 184.069 273.754 1.00 205.54 ? 84  GLU C CA  1 
ATOM   6331  C C   . GLU C 3 40  ? 191.549 185.202 272.896 1.00 205.54 ? 84  GLU C C   1 
ATOM   6332  O O   . GLU C 3 40  ? 192.473 185.008 272.104 1.00 205.54 ? 84  GLU C O   1 
ATOM   6333  C CB  . GLU C 3 40  ? 192.120 183.245 274.377 1.00 205.54 ? 84  GLU C CB  1 
ATOM   6334  C CG  . GLU C 3 40  ? 193.034 184.035 275.301 1.00 205.54 ? 84  GLU C CG  1 
ATOM   6335  C CD  . GLU C 3 40  ? 194.294 184.513 274.606 1.00 205.54 ? 84  GLU C CD  1 
ATOM   6336  O OE1 . GLU C 3 40  ? 194.715 183.867 273.624 1.00 205.54 ? 84  GLU C OE1 1 
ATOM   6337  O OE2 . GLU C 3 40  ? 194.863 185.536 275.042 1.00 205.54 ? 84  GLU C OE2 1 
ATOM   6338  N N   . ASN C 3 41  ? 190.976 186.393 273.053 1.00 216.01 ? 85  ASN C N   1 
ATOM   6339  C CA  . ASN C 3 41  ? 191.389 187.550 272.268 1.00 216.01 ? 85  ASN C CA  1 
ATOM   6340  C C   . ASN C 3 41  ? 191.639 188.746 273.177 1.00 216.01 ? 85  ASN C C   1 
ATOM   6341  O O   . ASN C 3 41  ? 191.691 188.599 274.403 1.00 216.01 ? 85  ASN C O   1 
ATOM   6342  C CB  . ASN C 3 41  ? 190.335 187.887 271.212 1.00 216.01 ? 85  ASN C CB  1 
ATOM   6343  C CG  . ASN C 3 41  ? 190.945 188.402 269.923 1.00 216.01 ? 85  ASN C CG  1 
ATOM   6344  O OD1 . ASN C 3 41  ? 192.026 188.991 269.926 1.00 216.01 ? 85  ASN C OD1 1 
ATOM   6345  N ND2 . ASN C 3 41  ? 190.253 188.181 268.811 1.00 216.01 ? 85  ASN C ND2 1 
ATOM   6346  N N   . ARG C 3 42  ? 191.807 189.932 272.584 1.00 234.79 ? 86  ARG C N   1 
ATOM   6347  C CA  . ARG C 3 42  ? 192.044 191.132 273.380 1.00 234.79 ? 86  ARG C CA  1 
ATOM   6348  C C   . ARG C 3 42  ? 190.881 191.421 274.320 1.00 234.79 ? 86  ARG C C   1 
ATOM   6349  O O   . ARG C 3 42  ? 191.091 191.909 275.436 1.00 234.79 ? 86  ARG C O   1 
ATOM   6350  C CB  . ARG C 3 42  ? 192.295 192.331 272.465 1.00 234.79 ? 86  ARG C CB  1 
ATOM   6351  C CG  . ARG C 3 42  ? 193.271 192.066 271.327 1.00 234.79 ? 86  ARG C CG  1 
ATOM   6352  C CD  . ARG C 3 42  ? 194.598 191.523 271.836 1.00 234.79 ? 86  ARG C CD  1 
ATOM   6353  N NE  . ARG C 3 42  ? 194.715 190.084 271.623 1.00 234.79 ? 86  ARG C NE  1 
ATOM   6354  C CZ  . ARG C 3 42  ? 195.140 189.528 270.494 1.00 234.79 ? 86  ARG C CZ  1 
ATOM   6355  N NH1 . ARG C 3 42  ? 195.493 190.291 269.468 1.00 234.79 ? 86  ARG C NH1 1 
ATOM   6356  N NH2 . ARG C 3 42  ? 195.214 188.208 270.388 1.00 234.79 ? 86  ARG C NH2 1 
ATOM   6357  N N   . SER C 3 43  ? 189.654 191.130 273.892 1.00 256.24 ? 87  SER C N   1 
ATOM   6358  C CA  . SER C 3 43  ? 188.466 191.308 274.717 1.00 256.24 ? 87  SER C CA  1 
ATOM   6359  C C   . SER C 3 43  ? 187.740 189.975 274.810 1.00 256.24 ? 87  SER C C   1 
ATOM   6360  O O   . SER C 3 43  ? 187.237 189.469 273.802 1.00 256.24 ? 87  SER C O   1 
ATOM   6361  C CB  . SER C 3 43  ? 187.545 192.386 274.137 1.00 256.24 ? 87  SER C CB  1 
ATOM   6362  O OG  . SER C 3 43  ? 188.284 193.528 273.740 1.00 256.24 ? 87  SER C OG  1 
ATOM   6363  N N   . ARG C 3 44  ? 187.688 189.410 276.014 1.00 238.61 ? 88  ARG C N   1 
ATOM   6364  C CA  . ARG C 3 44  ? 187.060 188.110 276.228 1.00 238.61 ? 88  ARG C CA  1 
ATOM   6365  C C   . ARG C 3 44  ? 185.546 188.279 276.223 1.00 238.61 ? 88  ARG C C   1 
ATOM   6366  O O   . ARG C 3 44  ? 184.966 188.787 277.188 1.00 238.61 ? 88  ARG C O   1 
ATOM   6367  C CB  . ARG C 3 44  ? 187.540 187.493 277.539 1.00 238.61 ? 88  ARG C CB  1 
ATOM   6368  C CG  . ARG C 3 44  ? 187.043 186.075 277.767 1.00 238.61 ? 88  ARG C CG  1 
ATOM   6369  C CD  . ARG C 3 44  ? 187.636 185.472 279.029 1.00 238.61 ? 88  ARG C CD  1 
ATOM   6370  N NE  . ARG C 3 44  ? 187.288 184.061 279.171 1.00 238.61 ? 88  ARG C NE  1 
ATOM   6371  C CZ  . ARG C 3 44  ? 187.687 183.290 280.177 1.00 238.61 ? 88  ARG C CZ  1 
ATOM   6372  N NH1 . ARG C 3 44  ? 188.449 183.793 281.138 1.00 238.61 ? 88  ARG C NH1 1 
ATOM   6373  N NH2 . ARG C 3 44  ? 187.322 182.016 280.224 1.00 238.61 ? 88  ARG C NH2 1 
ATOM   6374  N N   . SER C 3 45  ? 184.904 187.852 275.137 1.00 257.77 ? 89  SER C N   1 
ATOM   6375  C CA  . SER C 3 45  ? 183.449 187.898 275.002 1.00 257.77 ? 89  SER C CA  1 
ATOM   6376  C C   . SER C 3 45  ? 182.976 186.501 274.615 1.00 257.77 ? 89  SER C C   1 
ATOM   6377  O O   . SER C 3 45  ? 183.019 186.128 273.438 1.00 257.77 ? 89  SER C O   1 
ATOM   6378  C CB  . SER C 3 45  ? 183.022 188.937 273.970 1.00 257.77 ? 89  SER C CB  1 
ATOM   6379  O OG  . SER C 3 45  ? 181.719 188.666 273.482 1.00 257.77 ? 89  SER C OG  1 
ATOM   6380  N N   . CYS C 3 46  ? 182.525 185.732 275.601 1.00 254.13 ? 90  CYS C N   1 
ATOM   6381  C CA  . CYS C 3 46  ? 182.085 184.364 275.382 1.00 254.13 ? 90  CYS C CA  1 
ATOM   6382  C C   . CYS C 3 46  ? 180.564 184.296 275.314 1.00 254.13 ? 90  CYS C C   1 
ATOM   6383  O O   . CYS C 3 46  ? 179.858 185.060 275.977 1.00 254.13 ? 90  CYS C O   1 
ATOM   6384  C CB  . CYS C 3 46  ? 182.603 183.439 276.486 1.00 254.13 ? 90  CYS C CB  1 
ATOM   6385  S SG  . CYS C 3 46  ? 184.408 183.410 276.653 1.00 254.13 ? 90  CYS C SG  1 
ATOM   6386  N N   . TYR C 3 47  ? 180.070 183.369 274.502 1.00 280.85 ? 91  TYR C N   1 
ATOM   6387  C CA  . TYR C 3 47  ? 178.644 183.177 274.277 1.00 280.85 ? 91  TYR C CA  1 
ATOM   6388  C C   . TYR C 3 47  ? 178.238 181.773 274.717 1.00 280.85 ? 91  TYR C C   1 
ATOM   6389  O O   . TYR C 3 47  ? 179.053 180.988 275.209 1.00 280.85 ? 91  TYR C O   1 
ATOM   6390  C CB  . TYR C 3 47  ? 178.291 183.413 272.806 1.00 280.85 ? 91  TYR C CB  1 
ATOM   6391  C CG  . TYR C 3 47  ? 178.489 184.840 272.347 1.00 280.85 ? 91  TYR C CG  1 
ATOM   6392  C CD1 . TYR C 3 47  ? 177.535 185.814 272.610 1.00 280.85 ? 91  TYR C CD1 1 
ATOM   6393  C CD2 . TYR C 3 47  ? 179.632 185.213 271.651 1.00 280.85 ? 91  TYR C CD2 1 
ATOM   6394  C CE1 . TYR C 3 47  ? 177.712 187.119 272.192 1.00 280.85 ? 91  TYR C CE1 1 
ATOM   6395  C CE2 . TYR C 3 47  ? 179.818 186.516 271.230 1.00 280.85 ? 91  TYR C CE2 1 
ATOM   6396  C CZ  . TYR C 3 47  ? 178.856 187.465 271.503 1.00 280.85 ? 91  TYR C CZ  1 
ATOM   6397  O OH  . TYR C 3 47  ? 179.038 188.763 271.085 1.00 280.85 ? 91  TYR C OH  1 
ATOM   6398  N N   . GLN C 3 48  ? 176.957 181.463 274.532 1.00 313.01 ? 92  GLN C N   1 
ATOM   6399  C CA  . GLN C 3 48  ? 176.402 180.161 274.875 1.00 313.01 ? 92  GLN C CA  1 
ATOM   6400  C C   . GLN C 3 48  ? 175.548 179.669 273.717 1.00 313.01 ? 92  GLN C C   1 
ATOM   6401  O O   . GLN C 3 48  ? 174.643 180.378 273.265 1.00 313.01 ? 92  GLN C O   1 
ATOM   6402  C CB  . GLN C 3 48  ? 175.571 180.233 276.160 1.00 313.01 ? 92  GLN C CB  1 
ATOM   6403  C CG  . GLN C 3 48  ? 175.023 178.893 276.623 1.00 313.01 ? 92  GLN C CG  1 
ATOM   6404  C CD  . GLN C 3 48  ? 174.217 179.004 277.902 1.00 313.01 ? 92  GLN C CD  1 
ATOM   6405  O OE1 . GLN C 3 48  ? 174.045 180.094 278.448 1.00 313.01 ? 92  GLN C OE1 1 
ATOM   6406  N NE2 . GLN C 3 48  ? 173.718 177.873 278.388 1.00 313.01 ? 92  GLN C NE2 1 
ATOM   6407  N N   . LEU C 3 49  ? 175.835 178.458 273.242 1.00 325.32 ? 93  LEU C N   1 
ATOM   6408  C CA  . LEU C 3 49  ? 175.119 177.875 272.117 1.00 325.32 ? 93  LEU C CA  1 
ATOM   6409  C C   . LEU C 3 49  ? 174.755 176.434 272.450 1.00 325.32 ? 93  LEU C C   1 
ATOM   6410  O O   . LEU C 3 49  ? 175.262 175.846 273.409 1.00 325.32 ? 93  LEU C O   1 
ATOM   6411  C CB  . LEU C 3 49  ? 175.943 177.951 270.823 1.00 325.32 ? 93  LEU C CB  1 
ATOM   6412  C CG  . LEU C 3 49  ? 177.025 176.900 270.560 1.00 325.32 ? 93  LEU C CG  1 
ATOM   6413  C CD1 . LEU C 3 49  ? 177.562 177.053 269.146 1.00 325.32 ? 93  LEU C CD1 1 
ATOM   6414  C CD2 . LEU C 3 49  ? 178.159 176.998 271.568 1.00 325.32 ? 93  LEU C CD2 1 
ATOM   6415  N N   . GLU C 3 50  ? 173.863 175.864 271.638 1.00 342.08 ? 94  GLU C N   1 
ATOM   6416  C CA  . GLU C 3 50  ? 173.306 174.544 271.898 1.00 342.08 ? 94  GLU C CA  1 
ATOM   6417  C C   . GLU C 3 50  ? 173.866 173.449 271.001 1.00 342.08 ? 94  GLU C C   1 
ATOM   6418  O O   . GLU C 3 50  ? 173.734 172.269 271.344 1.00 342.08 ? 94  GLU C O   1 
ATOM   6419  C CB  . GLU C 3 50  ? 171.777 174.578 271.749 1.00 342.08 ? 94  GLU C CB  1 
ATOM   6420  C CG  . GLU C 3 50  ? 171.078 175.528 272.707 1.00 342.08 ? 94  GLU C CG  1 
ATOM   6421  C CD  . GLU C 3 50  ? 170.964 174.964 274.109 1.00 342.08 ? 94  GLU C CD  1 
ATOM   6422  O OE1 . GLU C 3 50  ? 171.067 173.729 274.262 1.00 342.08 ? 94  GLU C OE1 1 
ATOM   6423  O OE2 . GLU C 3 50  ? 170.771 175.754 275.056 1.00 342.08 ? 94  GLU C OE2 1 
ATOM   6424  N N   . LYS C 3 51  ? 174.480 173.796 269.875 1.00 290.53 ? 95  LYS C N   1 
ATOM   6425  C CA  . LYS C 3 51  ? 174.998 172.816 268.932 1.00 290.53 ? 95  LYS C CA  1 
ATOM   6426  C C   . LYS C 3 51  ? 176.514 172.934 268.834 1.00 290.53 ? 95  LYS C C   1 
ATOM   6427  O O   . LYS C 3 51  ? 177.130 173.848 269.387 1.00 290.53 ? 95  LYS C O   1 
ATOM   6428  C CB  . LYS C 3 51  ? 174.359 172.990 267.548 1.00 290.53 ? 95  LYS C CB  1 
ATOM   6429  C CG  . LYS C 3 51  ? 172.919 172.510 267.466 1.00 290.53 ? 95  LYS C CG  1 
ATOM   6430  C CD  . LYS C 3 51  ? 172.828 171.006 267.671 1.00 290.53 ? 95  LYS C CD  1 
ATOM   6431  C CE  . LYS C 3 51  ? 173.624 170.254 266.617 1.00 290.53 ? 95  LYS C CE  1 
ATOM   6432  N NZ  . LYS C 3 51  ? 173.583 168.782 266.836 1.00 290.53 ? 95  LYS C NZ  1 
ATOM   6433  N N   . THR C 3 52  ? 177.114 171.985 268.122 1.00 213.87 ? 96  THR C N   1 
ATOM   6434  C CA  . THR C 3 52  ? 178.563 171.964 267.918 1.00 213.87 ? 96  THR C CA  1 
ATOM   6435  C C   . THR C 3 52  ? 178.957 172.673 266.625 1.00 213.87 ? 96  THR C C   1 
ATOM   6436  O O   . THR C 3 52  ? 179.672 172.130 265.785 1.00 213.87 ? 96  THR C O   1 
ATOM   6437  C CB  . THR C 3 52  ? 179.069 170.527 267.930 1.00 213.87 ? 96  THR C CB  1 
ATOM   6438  O OG1 . THR C 3 52  ? 178.463 169.796 266.856 1.00 213.87 ? 96  THR C OG1 1 
ATOM   6439  C CG2 . THR C 3 52  ? 178.727 169.853 269.251 1.00 213.87 ? 96  THR C CG2 1 
ATOM   6440  N N   . SER C 3 53  ? 178.486 173.909 266.462 1.00 190.18 ? 97  SER C N   1 
ATOM   6441  C CA  . SER C 3 53  ? 178.806 174.702 265.276 1.00 190.18 ? 97  SER C CA  1 
ATOM   6442  C C   . SER C 3 53  ? 178.694 176.171 265.657 1.00 190.18 ? 97  SER C C   1 
ATOM   6443  O O   . SER C 3 53  ? 177.586 176.663 265.892 1.00 190.18 ? 97  SER C O   1 
ATOM   6444  C CB  . SER C 3 53  ? 177.874 174.360 264.117 1.00 190.18 ? 97  SER C CB  1 
ATOM   6445  O OG  . SER C 3 53  ? 177.725 172.960 263.959 1.00 190.18 ? 97  SER C OG  1 
ATOM   6446  N N   . ILE C 3 54  ? 179.828 176.864 265.710 1.00 170.31 ? 98  ILE C N   1 
ATOM   6447  C CA  . ILE C 3 54  ? 179.879 178.268 266.095 1.00 170.31 ? 98  ILE C CA  1 
ATOM   6448  C C   . ILE C 3 54  ? 180.338 179.088 264.896 1.00 170.31 ? 98  ILE C C   1 
ATOM   6449  O O   . ILE C 3 54  ? 181.209 178.658 264.132 1.00 170.31 ? 98  ILE C O   1 
ATOM   6450  C CB  . ILE C 3 54  ? 180.805 178.490 267.312 1.00 170.31 ? 98  ILE C CB  1 
ATOM   6451  C CG1 . ILE C 3 54  ? 180.780 179.954 267.756 1.00 170.31 ? 98  ILE C CG1 1 
ATOM   6452  C CG2 . ILE C 3 54  ? 182.227 178.033 267.009 1.00 170.31 ? 98  ILE C CG2 1 
ATOM   6453  C CD1 . ILE C 3 54  ? 181.560 180.220 269.025 1.00 170.31 ? 98  ILE C CD1 1 
ATOM   6454  N N   . LYS C 3 55  ? 179.731 180.260 264.723 1.00 169.86 ? 99  LYS C N   1 
ATOM   6455  C CA  . LYS C 3 55  ? 180.065 181.182 263.642 1.00 169.86 ? 99  LYS C CA  1 
ATOM   6456  C C   . LYS C 3 55  ? 180.767 182.389 264.251 1.00 169.86 ? 99  LYS C C   1 
ATOM   6457  O O   . LYS C 3 55  ? 180.127 183.224 264.900 1.00 169.86 ? 99  LYS C O   1 
ATOM   6458  C CB  . LYS C 3 55  ? 178.815 181.601 262.871 1.00 169.86 ? 99  LYS C CB  1 
ATOM   6459  C CG  . LYS C 3 55  ? 178.372 180.609 261.805 1.00 169.86 ? 99  LYS C CG  1 
ATOM   6460  C CD  . LYS C 3 55  ? 177.552 179.475 262.401 1.00 169.86 ? 99  LYS C CD  1 
ATOM   6461  C CE  . LYS C 3 55  ? 176.282 179.995 263.055 1.00 169.86 ? 99  LYS C CE  1 
ATOM   6462  N NZ  . LYS C 3 55  ? 175.463 178.893 263.631 1.00 169.86 ? 99  LYS C NZ  1 
ATOM   6463  N N   . ILE C 3 56  ? 182.076 182.479 264.043 1.00 160.16 ? 100 ILE C N   1 
ATOM   6464  C CA  . ILE C 3 56  ? 182.882 183.548 264.626 1.00 160.16 ? 100 ILE C CA  1 
ATOM   6465  C C   . ILE C 3 56  ? 183.362 184.474 263.514 1.00 160.16 ? 100 ILE C C   1 
ATOM   6466  O O   . ILE C 3 56  ? 183.517 184.033 262.366 1.00 160.16 ? 100 ILE C O   1 
ATOM   6467  C CB  . ILE C 3 56  ? 184.059 182.976 265.431 1.00 160.16 ? 100 ILE C CB  1 
ATOM   6468  C CG1 . ILE C 3 56  ? 185.089 182.335 264.499 1.00 160.16 ? 100 ILE C CG1 1 
ATOM   6469  C CG2 . ILE C 3 56  ? 183.559 181.956 266.438 1.00 160.16 ? 100 ILE C CG2 1 
ATOM   6470  C CD1 . ILE C 3 56  ? 186.299 181.777 265.216 1.00 160.16 ? 100 ILE C CD1 1 
ATOM   6471  N N   . PRO C 3 57  ? 183.593 185.755 263.794 1.00 158.01 ? 101 PRO C N   1 
ATOM   6472  C CA  . PRO C 3 57  ? 184.083 186.663 262.751 1.00 158.01 ? 101 PRO C CA  1 
ATOM   6473  C C   . PRO C 3 57  ? 185.535 186.374 262.402 1.00 158.01 ? 101 PRO C C   1 
ATOM   6474  O O   . PRO C 3 57  ? 186.251 185.654 263.102 1.00 158.01 ? 101 PRO C O   1 
ATOM   6475  C CB  . PRO C 3 57  ? 183.922 188.049 263.381 1.00 158.01 ? 101 PRO C CB  1 
ATOM   6476  C CG  . PRO C 3 57  ? 183.987 187.798 264.848 1.00 158.01 ? 101 PRO C CG  1 
ATOM   6477  C CD  . PRO C 3 57  ? 183.344 186.456 265.066 1.00 158.01 ? 101 PRO C CD  1 
ATOM   6478  N N   . ALA C 3 58  ? 185.967 186.958 261.287 1.00 169.79 ? 102 ALA C N   1 
ATOM   6479  C CA  . ALA C 3 58  ? 187.340 186.789 260.828 1.00 169.79 ? 102 ALA C CA  1 
ATOM   6480  C C   . ALA C 3 58  ? 188.289 187.563 261.734 1.00 169.79 ? 102 ALA C C   1 
ATOM   6481  O O   . ALA C 3 58  ? 188.176 188.787 261.865 1.00 169.79 ? 102 ALA C O   1 
ATOM   6482  C CB  . ALA C 3 58  ? 187.476 187.256 259.381 1.00 169.79 ? 102 ALA C CB  1 
ATOM   6483  N N   . LEU C 3 59  ? 189.222 186.852 262.358 1.00 175.36 ? 103 LEU C N   1 
ATOM   6484  C CA  . LEU C 3 59  ? 190.186 187.463 263.257 1.00 175.36 ? 103 LEU C CA  1 
ATOM   6485  C C   . LEU C 3 59  ? 191.427 187.911 262.489 1.00 175.36 ? 103 LEU C C   1 
ATOM   6486  O O   . LEU C 3 59  ? 191.518 187.784 261.267 1.00 175.36 ? 103 LEU C O   1 
ATOM   6487  C CB  . LEU C 3 59  ? 190.567 186.488 264.371 1.00 175.36 ? 103 LEU C CB  1 
ATOM   6488  C CG  . LEU C 3 59  ? 189.408 185.946 265.210 1.00 175.36 ? 103 LEU C CG  1 
ATOM   6489  C CD1 . LEU C 3 59  ? 189.905 184.926 266.222 1.00 175.36 ? 103 LEU C CD1 1 
ATOM   6490  C CD2 . LEU C 3 59  ? 188.672 187.081 265.905 1.00 175.36 ? 103 LEU C CD2 1 
ATOM   6491  N N   . SER C 3 60  ? 192.394 188.446 263.230 1.00 178.30 ? 104 SER C N   1 
ATOM   6492  C CA  . SER C 3 60  ? 193.637 188.916 262.640 1.00 178.30 ? 104 SER C CA  1 
ATOM   6493  C C   . SER C 3 60  ? 194.591 187.744 262.410 1.00 178.30 ? 104 SER C C   1 
ATOM   6494  O O   . SER C 3 60  ? 194.289 186.588 262.717 1.00 178.30 ? 104 SER C O   1 
ATOM   6495  C CB  . SER C 3 60  ? 194.277 189.980 263.530 1.00 178.30 ? 104 SER C CB  1 
ATOM   6496  O OG  . SER C 3 60  ? 195.665 190.095 263.269 1.00 178.30 ? 104 SER C OG  1 
ATOM   6497  N N   . HIS C 3 61  ? 195.763 188.051 261.859 1.00 178.70 ? 105 HIS C N   1 
ATOM   6498  C CA  . HIS C 3 61  ? 196.773 187.035 261.591 1.00 178.70 ? 105 HIS C CA  1 
ATOM   6499  C C   . HIS C 3 61  ? 197.473 186.655 262.890 1.00 178.70 ? 105 HIS C C   1 
ATOM   6500  O O   . HIS C 3 61  ? 198.095 187.504 263.538 1.00 178.70 ? 105 HIS C O   1 
ATOM   6501  C CB  . HIS C 3 61  ? 197.781 187.543 260.563 1.00 178.70 ? 105 HIS C CB  1 
ATOM   6502  C CG  . HIS C 3 61  ? 197.170 187.916 259.249 1.00 178.70 ? 105 HIS C CG  1 
ATOM   6503  N ND1 . HIS C 3 61  ? 196.977 187.005 258.233 1.00 178.70 ? 105 HIS C ND1 1 
ATOM   6504  C CD2 . HIS C 3 61  ? 196.710 189.101 258.783 1.00 178.70 ? 105 HIS C CD2 1 
ATOM   6505  C CE1 . HIS C 3 61  ? 196.423 187.613 257.198 1.00 178.70 ? 105 HIS C CE1 1 
ATOM   6506  N NE2 . HIS C 3 61  ? 196.251 188.886 257.507 1.00 178.70 ? 105 HIS C NE2 1 
ATOM   6507  N N   . GLY C 3 62  ? 197.372 185.393 263.267 1.00 192.63 ? 106 GLY C N   1 
ATOM   6508  C CA  . GLY C 3 62  ? 198.007 184.909 264.478 1.00 192.63 ? 106 GLY C CA  1 
ATOM   6509  C C   . GLY C 3 62  ? 197.264 183.717 265.041 1.00 192.63 ? 106 GLY C C   1 
ATOM   6510  O O   . GLY C 3 62  ? 196.186 183.344 264.582 1.00 192.63 ? 106 GLY C O   1 
ATOM   6511  N N   . ASP C 3 63  ? 197.869 183.117 266.062 1.00 197.78 ? 107 ASP C N   1 
ATOM   6512  C CA  . ASP C 3 63  ? 197.296 181.958 266.731 1.00 197.78 ? 107 ASP C CA  1 
ATOM   6513  C C   . ASP C 3 63  ? 196.336 182.415 267.822 1.00 197.78 ? 107 ASP C C   1 
ATOM   6514  O O   . ASP C 3 63  ? 196.650 183.326 268.593 1.00 197.78 ? 107 ASP C O   1 
ATOM   6515  C CB  . ASP C 3 63  ? 198.394 181.078 267.328 1.00 197.78 ? 107 ASP C CB  1 
ATOM   6516  C CG  . ASP C 3 63  ? 198.969 180.101 266.321 1.00 197.78 ? 107 ASP C CG  1 
ATOM   6517  O OD1 . ASP C 3 63  ? 198.511 180.105 265.159 1.00 197.78 ? 107 ASP C OD1 1 
ATOM   6518  O OD2 . ASP C 3 63  ? 199.877 179.328 266.693 1.00 197.78 ? 107 ASP C OD2 1 
ATOM   6519  N N   . TYR C 3 64  ? 195.169 181.779 267.880 1.00 189.37 ? 108 TYR C N   1 
ATOM   6520  C CA  . TYR C 3 64  ? 194.144 182.096 268.862 1.00 189.37 ? 108 TYR C CA  1 
ATOM   6521  C C   . TYR C 3 64  ? 193.790 180.848 269.656 1.00 189.37 ? 108 TYR C C   1 
ATOM   6522  O O   . TYR C 3 64  ? 193.760 179.740 269.109 1.00 189.37 ? 108 TYR C O   1 
ATOM   6523  C CB  . TYR C 3 64  ? 192.891 182.663 268.189 1.00 189.37 ? 108 TYR C CB  1 
ATOM   6524  C CG  . TYR C 3 64  ? 193.076 184.054 267.626 1.00 189.37 ? 108 TYR C CG  1 
ATOM   6525  C CD1 . TYR C 3 64  ? 192.752 185.176 268.377 1.00 189.37 ? 108 TYR C CD1 1 
ATOM   6526  C CD2 . TYR C 3 64  ? 193.575 184.245 266.344 1.00 189.37 ? 108 TYR C CD2 1 
ATOM   6527  C CE1 . TYR C 3 64  ? 192.920 186.450 267.867 1.00 189.37 ? 108 TYR C CE1 1 
ATOM   6528  C CE2 . TYR C 3 64  ? 193.746 185.515 265.825 1.00 189.37 ? 108 TYR C CE2 1 
ATOM   6529  C CZ  . TYR C 3 64  ? 193.416 186.613 266.591 1.00 189.37 ? 108 TYR C CZ  1 
ATOM   6530  O OH  . TYR C 3 64  ? 193.584 187.879 266.080 1.00 189.37 ? 108 TYR C OH  1 
ATOM   6531  N N   . GLU C 3 65  ? 193.524 181.032 270.945 1.00 182.11 ? 109 GLU C N   1 
ATOM   6532  C CA  . GLU C 3 65  ? 193.170 179.939 271.839 1.00 182.11 ? 109 GLU C CA  1 
ATOM   6533  C C   . GLU C 3 65  ? 191.655 179.827 271.934 1.00 182.11 ? 109 GLU C C   1 
ATOM   6534  O O   . GLU C 3 65  ? 190.971 180.812 272.230 1.00 182.11 ? 109 GLU C O   1 
ATOM   6535  C CB  . GLU C 3 65  ? 193.774 180.153 273.228 1.00 182.11 ? 109 GLU C CB  1 
ATOM   6536  C CG  . GLU C 3 65  ? 193.329 179.131 274.262 1.00 182.11 ? 109 GLU C CG  1 
ATOM   6537  C CD  . GLU C 3 65  ? 193.940 179.379 275.627 1.00 182.11 ? 109 GLU C CD  1 
ATOM   6538  O OE1 . GLU C 3 65  ? 194.983 180.063 275.698 1.00 182.11 ? 109 GLU C OE1 1 
ATOM   6539  O OE2 . GLU C 3 65  ? 193.378 178.890 276.629 1.00 182.11 ? 109 GLU C OE2 1 
ATOM   6540  N N   . ILE C 3 66  ? 191.136 178.628 271.682 1.00 180.13 ? 110 ILE C N   1 
ATOM   6541  C CA  . ILE C 3 66  ? 189.705 178.352 271.730 1.00 180.13 ? 110 ILE C CA  1 
ATOM   6542  C C   . ILE C 3 66  ? 189.466 177.302 272.805 1.00 180.13 ? 110 ILE C C   1 
ATOM   6543  O O   . ILE C 3 66  ? 189.963 176.174 272.700 1.00 180.13 ? 110 ILE C O   1 
ATOM   6544  C CB  . ILE C 3 66  ? 189.162 177.878 270.372 1.00 180.13 ? 110 ILE C CB  1 
ATOM   6545  C CG1 . ILE C 3 66  ? 189.284 178.985 269.320 1.00 180.13 ? 110 ILE C CG1 1 
ATOM   6546  C CG2 . ILE C 3 66  ? 187.717 177.424 270.506 1.00 180.13 ? 110 ILE C CG2 1 
ATOM   6547  C CD1 . ILE C 3 66  ? 190.578 178.954 268.530 1.00 180.13 ? 110 ILE C CD1 1 
ATOM   6548  N N   . THR C 3 67  ? 188.709 177.671 273.834 1.00 185.14 ? 111 THR C N   1 
ATOM   6549  C CA  . THR C 3 67  ? 188.407 176.790 274.953 1.00 185.14 ? 111 THR C CA  1 
ATOM   6550  C C   . THR C 3 67  ? 186.934 176.408 274.918 1.00 185.14 ? 111 THR C C   1 
ATOM   6551  O O   . THR C 3 67  ? 186.062 177.283 274.883 1.00 185.14 ? 111 THR C O   1 
ATOM   6552  C CB  . THR C 3 67  ? 188.747 177.458 276.287 1.00 185.14 ? 111 THR C CB  1 
ATOM   6553  O OG1 . THR C 3 67  ? 190.143 177.777 276.323 1.00 185.14 ? 111 THR C OG1 1 
ATOM   6554  C CG2 . THR C 3 67  ? 188.414 176.532 277.447 1.00 185.14 ? 111 THR C CG2 1 
ATOM   6555  N N   . ILE C 3 68  ? 186.662 175.105 274.929 1.00 191.94 ? 112 ILE C N   1 
ATOM   6556  C CA  . ILE C 3 68  ? 185.301 174.584 274.913 1.00 191.94 ? 112 ILE C CA  1 
ATOM   6557  C C   . ILE C 3 68  ? 184.889 174.240 276.336 1.00 191.94 ? 112 ILE C C   1 
ATOM   6558  O O   . ILE C 3 68  ? 185.722 173.910 277.188 1.00 191.94 ? 112 ILE C O   1 
ATOM   6559  C CB  . ILE C 3 68  ? 185.173 173.357 273.984 1.00 191.94 ? 112 ILE C CB  1 
ATOM   6560  C CG1 . ILE C 3 68  ? 186.068 172.216 274.475 1.00 191.94 ? 112 ILE C CG1 1 
ATOM   6561  C CG2 . ILE C 3 68  ? 185.523 173.732 272.553 1.00 191.94 ? 112 ILE C CG2 1 
ATOM   6562  C CD1 . ILE C 3 68  ? 185.946 170.950 273.655 1.00 191.94 ? 112 ILE C CD1 1 
ATOM   6563  N N   . ASN C 3 69  ? 183.585 174.320 276.599 1.00 214.46 ? 113 ASN C N   1 
ATOM   6564  C CA  . ASN C 3 69  ? 183.036 174.037 277.922 1.00 214.46 ? 113 ASN C CA  1 
ATOM   6565  C C   . ASN C 3 69  ? 181.719 173.294 277.748 1.00 214.46 ? 113 ASN C C   1 
ATOM   6566  O O   . ASN C 3 69  ? 180.697 173.908 277.423 1.00 214.46 ? 113 ASN C O   1 
ATOM   6567  C CB  . ASN C 3 69  ? 182.833 175.323 278.725 1.00 214.46 ? 113 ASN C CB  1 
ATOM   6568  C CG  . ASN C 3 69  ? 184.141 175.953 279.159 1.00 214.46 ? 113 ASN C CG  1 
ATOM   6569  O OD1 . ASN C 3 69  ? 185.046 175.267 279.635 1.00 214.46 ? 113 ASN C OD1 1 
ATOM   6570  N ND2 . ASN C 3 69  ? 184.248 177.266 278.996 1.00 214.46 ? 113 ASN C ND2 1 
ATOM   6571  N N   . SER C 3 70  ? 181.742 171.982 277.963 1.00 243.30 ? 114 SER C N   1 
ATOM   6572  C CA  . SER C 3 70  ? 180.532 171.173 277.886 1.00 243.30 ? 114 SER C CA  1 
ATOM   6573  C C   . SER C 3 70  ? 179.778 171.269 279.207 1.00 243.30 ? 114 SER C C   1 
ATOM   6574  O O   . SER C 3 70  ? 180.252 170.778 280.237 1.00 243.30 ? 114 SER C O   1 
ATOM   6575  C CB  . SER C 3 70  ? 180.878 169.722 277.563 1.00 243.30 ? 114 SER C CB  1 
ATOM   6576  O OG  . SER C 3 70  ? 181.098 169.546 276.174 1.00 243.30 ? 114 SER C OG  1 
ATOM   6577  N N   . LEU C 3 71  ? 178.606 171.898 279.177 1.00 274.21 ? 115 LEU C N   1 
ATOM   6578  C CA  . LEU C 3 71  ? 177.809 172.123 280.379 1.00 274.21 ? 115 LEU C CA  1 
ATOM   6579  C C   . LEU C 3 71  ? 176.896 170.922 280.600 1.00 274.21 ? 115 LEU C C   1 
ATOM   6580  O O   . LEU C 3 71  ? 176.005 170.651 279.788 1.00 274.21 ? 115 LEU C O   1 
ATOM   6581  C CB  . LEU C 3 71  ? 177.003 173.413 280.255 1.00 274.21 ? 115 LEU C CB  1 
ATOM   6582  C CG  . LEU C 3 71  ? 177.804 174.682 279.958 1.00 274.21 ? 115 LEU C CG  1 
ATOM   6583  C CD1 . LEU C 3 71  ? 176.885 175.890 279.854 1.00 274.21 ? 115 LEU C CD1 1 
ATOM   6584  C CD2 . LEU C 3 71  ? 178.872 174.906 281.018 1.00 274.21 ? 115 LEU C CD2 1 
ATOM   6585  N N   . HIS C 3 72  ? 177.119 170.203 281.697 1.00 306.74 ? 116 HIS C N   1 
ATOM   6586  C CA  . HIS C 3 72  ? 176.314 169.050 282.067 1.00 306.74 ? 116 HIS C CA  1 
ATOM   6587  C C   . HIS C 3 72  ? 175.955 169.137 283.544 1.00 306.74 ? 116 HIS C C   1 
ATOM   6588  O O   . HIS C 3 72  ? 176.470 169.978 284.286 1.00 306.74 ? 116 HIS C O   1 
ATOM   6589  C CB  . HIS C 3 72  ? 177.046 167.733 281.777 1.00 306.74 ? 116 HIS C CB  1 
ATOM   6590  C CG  . HIS C 3 72  ? 177.303 167.492 280.323 1.00 306.74 ? 116 HIS C CG  1 
ATOM   6591  N ND1 . HIS C 3 72  ? 176.458 166.744 279.532 1.00 306.74 ? 116 HIS C ND1 1 
ATOM   6592  C CD2 . HIS C 3 72  ? 178.313 167.897 279.517 1.00 306.74 ? 116 HIS C CD2 1 
ATOM   6593  C CE1 . HIS C 3 72  ? 176.935 166.699 278.301 1.00 306.74 ? 116 HIS C CE1 1 
ATOM   6594  N NE2 . HIS C 3 72  ? 178.060 167.391 278.265 1.00 306.74 ? 116 HIS C NE2 1 
ATOM   6595  N N   . ASP C 3 73  ? 175.057 168.251 283.967 1.00 373.36 ? 117 ASP C N   1 
ATOM   6596  C CA  . ASP C 3 73  ? 174.645 168.164 285.361 1.00 373.36 ? 117 ASP C CA  1 
ATOM   6597  C C   . ASP C 3 73  ? 175.489 167.187 286.168 1.00 373.36 ? 117 ASP C C   1 
ATOM   6598  O O   . ASP C 3 73  ? 175.210 166.984 287.355 1.00 373.36 ? 117 ASP C O   1 
ATOM   6599  C CB  . ASP C 3 73  ? 173.167 167.766 285.449 1.00 373.36 ? 117 ASP C CB  1 
ATOM   6600  C CG  . ASP C 3 73  ? 172.795 166.683 284.455 1.00 373.36 ? 117 ASP C CG  1 
ATOM   6601  O OD1 . ASP C 3 73  ? 173.708 166.006 283.938 1.00 373.36 ? 117 ASP C OD1 1 
ATOM   6602  O OD2 . ASP C 3 73  ? 171.586 166.507 284.192 1.00 373.36 ? 117 ASP C OD2 1 
ATOM   6603  N N   . PHE C 3 74  ? 176.508 166.579 285.559 1.00 358.11 ? 118 PHE C N   1 
ATOM   6604  C CA  . PHE C 3 74  ? 177.385 165.640 286.248 1.00 358.11 ? 118 PHE C CA  1 
ATOM   6605  C C   . PHE C 3 74  ? 178.852 166.042 286.164 1.00 358.11 ? 118 PHE C C   1 
ATOM   6606  O O   . PHE C 3 74  ? 179.720 165.270 286.590 1.00 358.11 ? 118 PHE C O   1 
ATOM   6607  C CB  . PHE C 3 74  ? 177.199 164.227 285.686 1.00 358.11 ? 118 PHE C CB  1 
ATOM   6608  C CG  . PHE C 3 74  ? 176.013 163.500 286.252 1.00 358.11 ? 118 PHE C CG  1 
ATOM   6609  C CD1 . PHE C 3 74  ? 176.089 162.880 287.488 1.00 358.11 ? 118 PHE C CD1 1 
ATOM   6610  C CD2 . PHE C 3 74  ? 174.822 163.436 285.548 1.00 358.11 ? 118 PHE C CD2 1 
ATOM   6611  C CE1 . PHE C 3 74  ? 174.999 162.210 288.012 1.00 358.11 ? 118 PHE C CE1 1 
ATOM   6612  C CE2 . PHE C 3 74  ? 173.728 162.769 286.067 1.00 358.11 ? 118 PHE C CE2 1 
ATOM   6613  C CZ  . PHE C 3 74  ? 173.817 162.155 287.300 1.00 358.11 ? 118 PHE C CZ  1 
ATOM   6614  N N   . GLY C 3 75  ? 179.150 167.215 285.635 1.00 297.73 ? 119 GLY C N   1 
ATOM   6615  C CA  . GLY C 3 75  ? 180.515 167.687 285.494 1.00 297.73 ? 119 GLY C CA  1 
ATOM   6616  C C   . GLY C 3 75  ? 180.698 168.429 284.184 1.00 297.73 ? 119 GLY C C   1 
ATOM   6617  O O   . GLY C 3 75  ? 179.880 168.351 283.267 1.00 297.73 ? 119 GLY C O   1 
ATOM   6618  N N   . SER C 3 76  ? 181.800 169.167 284.096 1.00 228.04 ? 120 SER C N   1 
ATOM   6619  C CA  . SER C 3 76  ? 182.123 169.960 282.920 1.00 228.04 ? 120 SER C CA  1 
ATOM   6620  C C   . SER C 3 76  ? 183.464 169.524 282.347 1.00 228.04 ? 120 SER C C   1 
ATOM   6621  O O   . SER C 3 76  ? 184.338 169.035 283.069 1.00 228.04 ? 120 SER C O   1 
ATOM   6622  C CB  . SER C 3 76  ? 182.161 171.458 283.252 1.00 228.04 ? 120 SER C CB  1 
ATOM   6623  O OG  . SER C 3 76  ? 182.922 172.172 282.293 1.00 228.04 ? 120 SER C OG  1 
ATOM   6624  N N   . SER C 3 77  ? 183.616 169.706 281.039 1.00 190.42 ? 121 SER C N   1 
ATOM   6625  C CA  . SER C 3 77  ? 184.841 169.369 280.329 1.00 190.42 ? 121 SER C CA  1 
ATOM   6626  C C   . SER C 3 77  ? 185.464 170.632 279.752 1.00 190.42 ? 121 SER C C   1 
ATOM   6627  O O   . SER C 3 77  ? 184.762 171.487 279.202 1.00 190.42 ? 121 SER C O   1 
ATOM   6628  C CB  . SER C 3 77  ? 184.568 168.361 279.209 1.00 190.42 ? 121 SER C CB  1 
ATOM   6629  O OG  . SER C 3 77  ? 184.066 169.009 278.053 1.00 190.42 ? 121 SER C OG  1 
ATOM   6630  N N   . THR C 3 78  ? 186.784 170.746 279.880 1.00 181.22 ? 122 THR C N   1 
ATOM   6631  C CA  . THR C 3 78  ? 187.523 171.911 279.410 1.00 181.22 ? 122 THR C CA  1 
ATOM   6632  C C   . THR C 3 78  ? 188.664 171.448 278.518 1.00 181.22 ? 122 THR C C   1 
ATOM   6633  O O   . THR C 3 78  ? 189.573 170.751 278.980 1.00 181.22 ? 122 THR C O   1 
ATOM   6634  C CB  . THR C 3 78  ? 188.062 172.737 280.582 1.00 181.22 ? 122 THR C CB  1 
ATOM   6635  O OG1 . THR C 3 78  ? 186.969 173.224 281.370 1.00 181.22 ? 122 THR C OG1 1 
ATOM   6636  C CG2 . THR C 3 78  ? 188.879 173.915 280.073 1.00 181.22 ? 122 THR C CG2 1 
ATOM   6637  N N   . SER C 3 79  ? 188.616 171.836 277.245 1.00 166.89 ? 123 SER C N   1 
ATOM   6638  C CA  . SER C 3 79  ? 189.663 171.522 276.285 1.00 166.89 ? 123 SER C CA  1 
ATOM   6639  C C   . SER C 3 79  ? 190.013 172.774 275.495 1.00 166.89 ? 123 SER C C   1 
ATOM   6640  O O   . SER C 3 79  ? 189.162 173.634 275.254 1.00 166.89 ? 123 SER C O   1 
ATOM   6641  C CB  . SER C 3 79  ? 189.237 170.399 275.329 1.00 166.89 ? 123 SER C CB  1 
ATOM   6642  O OG  . SER C 3 79  ? 190.361 169.824 274.686 1.00 166.89 ? 123 SER C OG  1 
ATOM   6643  N N   . LYS C 3 80  ? 191.276 172.867 275.091 1.00 152.00 ? 124 LYS C N   1 
ATOM   6644  C CA  . LYS C 3 80  ? 191.787 174.022 274.370 1.00 152.00 ? 124 LYS C CA  1 
ATOM   6645  C C   . LYS C 3 80  ? 192.165 173.636 272.945 1.00 152.00 ? 124 LYS C C   1 
ATOM   6646  O O   . LYS C 3 80  ? 192.562 172.499 272.674 1.00 152.00 ? 124 LYS C O   1 
ATOM   6647  C CB  . LYS C 3 80  ? 193.000 174.623 275.085 1.00 152.00 ? 124 LYS C CB  1 
ATOM   6648  C CG  . LYS C 3 80  ? 192.709 175.100 276.498 1.00 152.00 ? 124 LYS C CG  1 
ATOM   6649  C CD  . LYS C 3 80  ? 193.961 175.639 277.169 1.00 152.00 ? 124 LYS C CD  1 
ATOM   6650  C CE  . LYS C 3 80  ? 193.657 176.154 278.566 1.00 152.00 ? 124 LYS C CE  1 
ATOM   6651  N NZ  . LYS C 3 80  ? 194.855 176.766 279.204 1.00 152.00 ? 124 LYS C NZ  1 
ATOM   6652  N N   . PHE C 3 81  ? 192.035 174.600 272.036 1.00 162.36 ? 125 PHE C N   1 
ATOM   6653  C CA  . PHE C 3 81  ? 192.374 174.404 270.635 1.00 162.36 ? 125 PHE C CA  1 
ATOM   6654  C C   . PHE C 3 81  ? 193.088 175.641 270.113 1.00 162.36 ? 125 PHE C C   1 
ATOM   6655  O O   . PHE C 3 81  ? 192.832 176.762 270.562 1.00 162.36 ? 125 PHE C O   1 
ATOM   6656  C CB  . PHE C 3 81  ? 191.129 174.119 269.783 1.00 162.36 ? 125 PHE C CB  1 
ATOM   6657  C CG  . PHE C 3 81  ? 190.433 172.835 270.135 1.00 162.36 ? 125 PHE C CG  1 
ATOM   6658  C CD1 . PHE C 3 81  ? 190.810 171.643 269.539 1.00 162.36 ? 125 PHE C CD1 1 
ATOM   6659  C CD2 . PHE C 3 81  ? 189.401 172.820 271.058 1.00 162.36 ? 125 PHE C CD2 1 
ATOM   6660  C CE1 . PHE C 3 81  ? 190.172 170.459 269.859 1.00 162.36 ? 125 PHE C CE1 1 
ATOM   6661  C CE2 . PHE C 3 81  ? 188.759 171.640 271.383 1.00 162.36 ? 125 PHE C CE2 1 
ATOM   6662  C CZ  . PHE C 3 81  ? 189.145 170.458 270.782 1.00 162.36 ? 125 PHE C CZ  1 
ATOM   6663  N N   . THR C 3 82  ? 193.990 175.426 269.157 1.00 172.86 ? 126 THR C N   1 
ATOM   6664  C CA  . THR C 3 82  ? 194.768 176.496 268.540 1.00 172.86 ? 126 THR C CA  1 
ATOM   6665  C C   . THR C 3 82  ? 194.433 176.539 267.055 1.00 172.86 ? 126 THR C C   1 
ATOM   6666  O O   . THR C 3 82  ? 194.817 175.638 266.300 1.00 172.86 ? 126 THR C O   1 
ATOM   6667  C CB  . THR C 3 82  ? 196.266 176.283 268.756 1.00 172.86 ? 126 THR C CB  1 
ATOM   6668  O OG1 . THR C 3 82  ? 196.543 176.212 270.160 1.00 172.86 ? 126 THR C OG1 1 
ATOM   6669  C CG2 . THR C 3 82  ? 197.060 177.429 268.145 1.00 172.86 ? 126 THR C CG2 1 
ATOM   6670  N N   . LEU C 3 83  ? 193.721 177.582 266.638 1.00 189.38 ? 127 LEU C N   1 
ATOM   6671  C CA  . LEU C 3 83  ? 193.317 177.758 265.251 1.00 189.38 ? 127 LEU C CA  1 
ATOM   6672  C C   . LEU C 3 83  ? 194.044 178.950 264.644 1.00 189.38 ? 127 LEU C C   1 
ATOM   6673  O O   . LEU C 3 83  ? 194.211 179.986 265.295 1.00 189.38 ? 127 LEU C O   1 
ATOM   6674  C CB  . LEU C 3 83  ? 191.802 177.958 265.141 1.00 189.38 ? 127 LEU C CB  1 
ATOM   6675  C CG  . LEU C 3 83  ? 191.224 178.076 263.729 1.00 189.38 ? 127 LEU C CG  1 
ATOM   6676  C CD1 . LEU C 3 83  ? 191.505 176.816 262.925 1.00 189.38 ? 127 LEU C CD1 1 
ATOM   6677  C CD2 . LEU C 3 83  ? 189.731 178.361 263.781 1.00 189.38 ? 127 LEU C CD2 1 
ATOM   6678  N N   . ASN C 3 84  ? 194.477 178.794 263.396 1.00 203.44 ? 128 ASN C N   1 
ATOM   6679  C CA  . ASN C 3 84  ? 195.169 179.841 262.660 1.00 203.44 ? 128 ASN C CA  1 
ATOM   6680  C C   . ASN C 3 84  ? 194.498 180.027 261.306 1.00 203.44 ? 128 ASN C C   1 
ATOM   6681  O O   . ASN C 3 84  ? 193.654 179.227 260.890 1.00 203.44 ? 128 ASN C O   1 
ATOM   6682  C CB  . ASN C 3 84  ? 196.657 179.508 262.482 1.00 203.44 ? 128 ASN C CB  1 
ATOM   6683  C CG  . ASN C 3 84  ? 197.510 180.743 262.265 1.00 203.44 ? 128 ASN C CG  1 
ATOM   6684  O OD1 . ASN C 3 84  ? 197.048 181.743 261.716 1.00 203.44 ? 128 ASN C OD1 1 
ATOM   6685  N ND2 . ASN C 3 84  ? 198.764 180.678 262.698 1.00 203.44 ? 128 ASN C ND2 1 
ATOM   6686  N N   . GLU C 3 85  ? 194.880 181.104 260.615 1.00 209.24 ? 129 GLU C N   1 
ATOM   6687  C CA  . GLU C 3 85  ? 194.329 181.359 259.288 1.00 209.24 ? 129 GLU C CA  1 
ATOM   6688  C C   . GLU C 3 85  ? 194.748 180.285 258.292 1.00 209.24 ? 129 GLU C C   1 
ATOM   6689  O O   . GLU C 3 85  ? 193.995 179.978 257.361 1.00 209.24 ? 129 GLU C O   1 
ATOM   6690  C CB  . GLU C 3 85  ? 194.760 182.739 258.790 1.00 209.24 ? 129 GLU C CB  1 
ATOM   6691  C CG  . GLU C 3 85  ? 193.947 183.250 257.610 1.00 209.24 ? 129 GLU C CG  1 
ATOM   6692  C CD  . GLU C 3 85  ? 194.536 184.502 256.990 1.00 209.24 ? 129 GLU C CD  1 
ATOM   6693  O OE1 . GLU C 3 85  ? 195.665 184.430 256.462 1.00 209.24 ? 129 GLU C OE1 1 
ATOM   6694  O OE2 . GLU C 3 85  ? 193.869 185.557 257.029 1.00 209.24 ? 129 GLU C OE2 1 
ATOM   6695  N N   . GLN C 3 86  ? 195.934 179.705 258.470 1.00 227.99 ? 130 GLN C N   1 
ATOM   6696  C CA  . GLN C 3 86  ? 196.400 178.638 257.597 1.00 227.99 ? 130 GLN C CA  1 
ATOM   6697  C C   . GLN C 3 86  ? 195.678 177.318 257.835 1.00 227.99 ? 130 GLN C C   1 
ATOM   6698  O O   . GLN C 3 86  ? 195.803 176.407 257.010 1.00 227.99 ? 130 GLN C O   1 
ATOM   6699  C CB  . GLN C 3 86  ? 197.908 178.436 257.773 1.00 227.99 ? 130 GLN C CB  1 
ATOM   6700  C CG  . GLN C 3 86  ? 198.737 179.677 257.489 1.00 227.99 ? 130 GLN C CG  1 
ATOM   6701  C CD  . GLN C 3 86  ? 200.219 179.456 257.727 1.00 227.99 ? 130 GLN C CD  1 
ATOM   6702  O OE1 . GLN C 3 86  ? 200.642 178.365 258.110 1.00 227.99 ? 130 GLN C OE1 1 
ATOM   6703  N NE2 . GLN C 3 86  ? 201.016 180.494 257.502 1.00 227.99 ? 130 GLN C NE2 1 
ATOM   6704  N N   . ASN C 3 87  ? 194.932 177.194 258.932 1.00 223.49 ? 131 ASN C N   1 
ATOM   6705  C CA  . ASN C 3 87  ? 194.208 175.970 259.247 1.00 223.49 ? 131 ASN C CA  1 
ATOM   6706  C C   . ASN C 3 87  ? 192.748 176.009 258.818 1.00 223.49 ? 131 ASN C C   1 
ATOM   6707  O O   . ASN C 3 87  ? 192.118 174.949 258.731 1.00 223.49 ? 131 ASN C O   1 
ATOM   6708  C CB  . ASN C 3 87  ? 194.285 175.682 260.752 1.00 223.49 ? 131 ASN C CB  1 
ATOM   6709  C CG  . ASN C 3 87  ? 195.711 175.534 261.246 1.00 223.49 ? 131 ASN C CG  1 
ATOM   6710  O OD1 . ASN C 3 87  ? 196.595 175.101 260.506 1.00 223.49 ? 131 ASN C OD1 1 
ATOM   6711  N ND2 . ASN C 3 87  ? 195.943 175.894 262.503 1.00 223.49 ? 131 ASN C ND2 1 
ATOM   6712  N N   . VAL C 3 88  ? 192.198 177.188 258.550 1.00 208.83 ? 132 VAL C N   1 
ATOM   6713  C CA  . VAL C 3 88  ? 190.806 177.306 258.133 1.00 208.83 ? 132 VAL C CA  1 
ATOM   6714  C C   . VAL C 3 88  ? 190.713 177.047 256.636 1.00 208.83 ? 132 VAL C C   1 
ATOM   6715  O O   . VAL C 3 88  ? 191.498 177.588 255.848 1.00 208.83 ? 132 VAL C O   1 
ATOM   6716  C CB  . VAL C 3 88  ? 190.244 178.689 258.496 1.00 208.83 ? 132 VAL C CB  1 
ATOM   6717  C CG1 . VAL C 3 88  ? 188.760 178.760 258.174 1.00 208.83 ? 132 VAL C CG1 1 
ATOM   6718  C CG2 . VAL C 3 88  ? 190.490 178.991 259.966 1.00 208.83 ? 132 VAL C CG2 1 
ATOM   6719  N N   . SER C 3 89  ? 189.752 176.217 256.240 1.00 221.02 ? 133 SER C N   1 
ATOM   6720  C CA  . SER C 3 89  ? 189.555 175.876 254.839 1.00 221.02 ? 133 SER C CA  1 
ATOM   6721  C C   . SER C 3 89  ? 188.561 176.832 254.194 1.00 221.02 ? 133 SER C C   1 
ATOM   6722  O O   . SER C 3 89  ? 187.564 177.223 254.810 1.00 221.02 ? 133 SER C O   1 
ATOM   6723  C CB  . SER C 3 89  ? 189.061 174.435 254.699 1.00 221.02 ? 133 SER C CB  1 
ATOM   6724  O OG  . SER C 3 89  ? 187.647 174.372 254.772 1.00 221.02 ? 133 SER C OG  1 
ATOM   6725  N N   . LEU C 3 90  ? 188.839 177.204 252.947 1.00 210.07 ? 134 LEU C N   1 
ATOM   6726  C CA  . LEU C 3 90  ? 187.989 178.107 252.179 1.00 210.07 ? 134 LEU C CA  1 
ATOM   6727  C C   . LEU C 3 90  ? 187.045 177.270 251.322 1.00 210.07 ? 134 LEU C C   1 
ATOM   6728  O O   . LEU C 3 90  ? 187.463 176.682 250.320 1.00 210.07 ? 134 LEU C O   1 
ATOM   6729  C CB  . LEU C 3 90  ? 188.833 179.045 251.318 1.00 210.07 ? 134 LEU C CB  1 
ATOM   6730  C CG  . LEU C 3 90  ? 188.098 180.059 250.440 1.00 210.07 ? 134 LEU C CG  1 
ATOM   6731  C CD1 . LEU C 3 90  ? 188.761 181.421 250.538 1.00 210.07 ? 134 LEU C CD1 1 
ATOM   6732  C CD2 . LEU C 3 90  ? 188.061 179.588 248.994 1.00 210.07 ? 134 LEU C CD2 1 
ATOM   6733  N N   . ILE C 3 91  ? 185.781 177.215 251.718 1.00 207.86 ? 135 ILE C N   1 
ATOM   6734  C CA  . ILE C 3 91  ? 184.751 176.485 250.993 1.00 207.86 ? 135 ILE C CA  1 
ATOM   6735  C C   . ILE C 3 91  ? 183.637 177.461 250.636 1.00 207.86 ? 135 ILE C C   1 
ATOM   6736  O O   . ILE C 3 91  ? 182.759 177.745 251.451 1.00 207.86 ? 135 ILE C O   1 
ATOM   6737  C CB  . ILE C 3 91  ? 184.210 175.302 251.816 1.00 207.86 ? 135 ILE C CB  1 
ATOM   6738  C CG1 . ILE C 3 91  ? 185.348 174.353 252.197 1.00 207.86 ? 135 ILE C CG1 1 
ATOM   6739  C CG2 . ILE C 3 91  ? 183.136 174.557 251.036 1.00 207.86 ? 135 ILE C CG2 1 
ATOM   6740  C CD1 . ILE C 3 91  ? 184.892 173.128 252.956 1.00 207.86 ? 135 ILE C CD1 1 
ATOM   6741  N N   . PRO C 3 92  ? 183.646 178.004 249.421 1.00 178.33 ? 136 PRO C N   1 
ATOM   6742  C CA  . PRO C 3 92  ? 182.581 178.928 249.013 1.00 178.33 ? 136 PRO C CA  1 
ATOM   6743  C C   . PRO C 3 92  ? 181.255 178.202 248.844 1.00 178.33 ? 136 PRO C C   1 
ATOM   6744  O O   . PRO C 3 92  ? 181.176 176.972 248.807 1.00 178.33 ? 136 PRO C O   1 
ATOM   6745  C CB  . PRO C 3 92  ? 183.082 179.493 247.678 1.00 178.33 ? 136 PRO C CB  1 
ATOM   6746  C CG  . PRO C 3 92  ? 184.545 179.148 247.623 1.00 178.33 ? 136 PRO C CG  1 
ATOM   6747  C CD  . PRO C 3 92  ? 184.688 177.875 248.392 1.00 178.33 ? 136 PRO C CD  1 
ATOM   6748  N N   . ASP C 3 93  ? 180.194 178.996 248.741 1.00 149.50 ? 137 ASP C N   1 
ATOM   6749  C CA  . ASP C 3 93  ? 178.862 178.443 248.547 1.00 149.50 ? 137 ASP C CA  1 
ATOM   6750  C C   . ASP C 3 93  ? 178.702 177.918 247.125 1.00 149.50 ? 137 ASP C C   1 
ATOM   6751  O O   . ASP C 3 93  ? 179.360 178.378 246.188 1.00 149.50 ? 137 ASP C O   1 
ATOM   6752  C CB  . ASP C 3 93  ? 177.796 179.498 248.840 1.00 149.50 ? 137 ASP C CB  1 
ATOM   6753  C CG  . ASP C 3 93  ? 177.707 179.843 250.313 1.00 149.50 ? 137 ASP C CG  1 
ATOM   6754  O OD1 . ASP C 3 93  ? 178.360 179.155 251.126 1.00 149.50 ? 137 ASP C OD1 1 
ATOM   6755  O OD2 . ASP C 3 93  ? 176.985 180.801 250.659 1.00 149.50 ? 137 ASP C OD2 1 
ATOM   6756  N N   . THR C 3 94  ? 177.815 176.940 246.973 1.00 109.56 ? 138 THR C N   1 
ATOM   6757  C CA  . THR C 3 94  ? 177.592 176.344 245.666 1.00 109.56 ? 138 THR C CA  1 
ATOM   6758  C C   . THR C 3 94  ? 176.852 177.323 244.756 1.00 109.56 ? 138 THR C C   1 
ATOM   6759  O O   . THR C 3 94  ? 175.978 178.064 245.217 1.00 109.56 ? 138 THR C O   1 
ATOM   6760  C CB  . THR C 3 94  ? 176.797 175.042 245.796 1.00 109.56 ? 138 THR C CB  1 
ATOM   6761  O OG1 . THR C 3 94  ? 176.454 174.553 244.494 1.00 109.56 ? 138 THR C OG1 1 
ATOM   6762  C CG2 . THR C 3 94  ? 175.527 175.260 246.610 1.00 109.56 ? 138 THR C CG2 1 
ATOM   6763  N N   . PRO C 3 95  ? 177.188 177.364 243.471 1.00 97.69  ? 139 PRO C N   1 
ATOM   6764  C CA  . PRO C 3 95  ? 176.458 178.230 242.542 1.00 97.69  ? 139 PRO C CA  1 
ATOM   6765  C C   . PRO C 3 95  ? 175.091 177.655 242.201 1.00 97.69  ? 139 PRO C C   1 
ATOM   6766  O O   . PRO C 3 95  ? 174.778 176.498 242.486 1.00 97.69  ? 139 PRO C O   1 
ATOM   6767  C CB  . PRO C 3 95  ? 177.364 178.266 241.306 1.00 97.69  ? 139 PRO C CB  1 
ATOM   6768  C CG  . PRO C 3 95  ? 178.106 176.975 241.359 1.00 97.69  ? 139 PRO C CG  1 
ATOM   6769  C CD  . PRO C 3 95  ? 178.309 176.666 242.818 1.00 97.69  ? 139 PRO C CD  1 
ATOM   6770  N N   . GLU C 3 96  ? 174.269 178.498 241.580 1.00 78.75  ? 140 GLU C N   1 
ATOM   6771  C CA  . GLU C 3 96  ? 172.913 178.119 241.206 1.00 78.75  ? 140 GLU C CA  1 
ATOM   6772  C C   . GLU C 3 96  ? 172.611 178.635 239.809 1.00 78.75  ? 140 GLU C C   1 
ATOM   6773  O O   . GLU C 3 96  ? 172.853 179.808 239.512 1.00 78.75  ? 140 GLU C O   1 
ATOM   6774  C CB  . GLU C 3 96  ? 171.890 178.667 242.208 1.00 78.75  ? 140 GLU C CB  1 
ATOM   6775  C CG  . GLU C 3 96  ? 170.511 178.040 242.092 1.00 78.75  ? 140 GLU C CG  1 
ATOM   6776  C CD  . GLU C 3 96  ? 169.546 178.562 243.137 1.00 78.75  ? 140 GLU C CD  1 
ATOM   6777  O OE1 . GLU C 3 96  ? 169.756 179.689 243.633 1.00 78.75  ? 140 GLU C OE1 1 
ATOM   6778  O OE2 . GLU C 3 96  ? 168.576 177.845 243.464 1.00 78.75  ? 140 GLU C OE2 1 
ATOM   6779  N N   . ILE C 3 97  ? 172.085 177.756 238.958 1.00 50.62  ? 141 ILE C N   1 
ATOM   6780  C CA  . ILE C 3 97  ? 171.746 178.134 237.590 1.00 50.62  ? 141 ILE C CA  1 
ATOM   6781  C C   . ILE C 3 97  ? 170.444 178.924 237.603 1.00 50.62  ? 141 ILE C C   1 
ATOM   6782  O O   . ILE C 3 97  ? 169.412 178.442 238.084 1.00 50.62  ? 141 ILE C O   1 
ATOM   6783  C CB  . ILE C 3 97  ? 171.638 176.897 236.690 1.00 50.62  ? 141 ILE C CB  1 
ATOM   6784  C CG1 . ILE C 3 97  ? 173.014 176.256 236.501 1.00 50.62  ? 141 ILE C CG1 1 
ATOM   6785  C CG2 . ILE C 3 97  ? 171.028 177.267 235.347 1.00 50.62  ? 141 ILE C CG2 1 
ATOM   6786  C CD1 . ILE C 3 97  ? 172.999 175.031 235.616 1.00 50.62  ? 141 ILE C CD1 1 
ATOM   6787  N N   . LEU C 3 98  ? 170.488 180.146 237.071 1.00 46.18  ? 142 LEU C N   1 
ATOM   6788  C CA  . LEU C 3 98  ? 169.302 180.997 237.047 1.00 46.18  ? 142 LEU C CA  1 
ATOM   6789  C C   . LEU C 3 98  ? 168.364 180.606 235.910 1.00 46.18  ? 142 LEU C C   1 
ATOM   6790  O O   . LEU C 3 98  ? 167.207 180.238 236.141 1.00 46.18  ? 142 LEU C O   1 
ATOM   6791  C CB  . LEU C 3 98  ? 169.711 182.468 236.928 1.00 46.18  ? 142 LEU C CB  1 
ATOM   6792  C CG  . LEU C 3 98  ? 170.017 183.213 238.230 1.00 46.18  ? 142 LEU C CG  1 
ATOM   6793  C CD1 . LEU C 3 98  ? 171.352 182.776 238.818 1.00 46.18  ? 142 LEU C CD1 1 
ATOM   6794  C CD2 . LEU C 3 98  ? 169.994 184.717 238.004 1.00 46.18  ? 142 LEU C CD2 1 
ATOM   6795  N N   . ASN C 3 99  ? 168.848 180.682 234.672 1.00 34.12  ? 143 ASN C N   1 
ATOM   6796  C CA  . ASN C 3 99  ? 168.049 180.350 233.504 1.00 34.12  ? 143 ASN C CA  1 
ATOM   6797  C C   . ASN C 3 99  ? 168.890 179.534 232.534 1.00 34.12  ? 143 ASN C C   1 
ATOM   6798  O O   . ASN C 3 99  ? 170.098 179.747 232.405 1.00 34.12  ? 143 ASN C O   1 
ATOM   6799  C CB  . ASN C 3 99  ? 167.515 181.611 232.809 1.00 34.12  ? 143 ASN C CB  1 
ATOM   6800  C CG  . ASN C 3 99  ? 166.563 181.292 231.673 1.00 34.12  ? 143 ASN C CG  1 
ATOM   6801  O OD1 . ASN C 3 99  ? 165.937 180.232 231.652 1.00 34.12  ? 143 ASN C OD1 1 
ATOM   6802  N ND2 . ASN C 3 99  ? 166.449 182.210 230.720 1.00 34.12  ? 143 ASN C ND2 1 
ATOM   6803  N N   . LEU C 3 100 ? 168.236 178.595 231.853 1.00 29.34  ? 144 LEU C N   1 
ATOM   6804  C CA  . LEU C 3 100 ? 168.891 177.719 230.887 1.00 29.34  ? 144 LEU C CA  1 
ATOM   6805  C C   . LEU C 3 100 ? 168.049 177.689 229.619 1.00 29.34  ? 144 LEU C C   1 
ATOM   6806  O O   . LEU C 3 100 ? 166.937 177.153 229.621 1.00 29.34  ? 144 LEU C O   1 
ATOM   6807  C CB  . LEU C 3 100 ? 169.077 176.311 231.455 1.00 29.34  ? 144 LEU C CB  1 
ATOM   6808  C CG  . LEU C 3 100 ? 169.995 175.359 230.684 1.00 29.34  ? 144 LEU C CG  1 
ATOM   6809  C CD1 . LEU C 3 100 ? 170.796 174.502 231.649 1.00 29.34  ? 144 LEU C CD1 1 
ATOM   6810  C CD2 . LEU C 3 100 ? 169.198 174.482 229.731 1.00 29.34  ? 144 LEU C CD2 1 
ATOM   6811  N N   . SER C 3 101 ? 168.579 178.259 228.541 1.00 23.56  ? 145 SER C N   1 
ATOM   6812  C CA  . SER C 3 101 ? 167.908 178.281 227.251 1.00 23.56  ? 145 SER C CA  1 
ATOM   6813  C C   . SER C 3 101 ? 168.798 177.637 226.198 1.00 23.56  ? 145 SER C C   1 
ATOM   6814  O O   . SER C 3 101 ? 170.027 177.655 226.305 1.00 23.56  ? 145 SER C O   1 
ATOM   6815  C CB  . SER C 3 101 ? 167.552 179.712 226.830 1.00 23.56  ? 145 SER C CB  1 
ATOM   6816  O OG  . SER C 3 101 ? 168.621 180.316 226.124 1.00 23.56  ? 145 SER C OG  1 
ATOM   6817  N N   . ALA C 3 102 ? 168.164 177.067 225.176 1.00 29.90  ? 146 ALA C N   1 
ATOM   6818  C CA  . ALA C 3 102 ? 168.877 176.381 224.108 1.00 29.90  ? 146 ALA C CA  1 
ATOM   6819  C C   . ALA C 3 102 ? 168.284 176.779 222.767 1.00 29.90  ? 146 ALA C C   1 
ATOM   6820  O O   . ALA C 3 102 ? 167.061 176.769 222.600 1.00 29.90  ? 146 ALA C O   1 
ATOM   6821  C CB  . ALA C 3 102 ? 168.809 174.860 224.285 1.00 29.90  ? 146 ALA C CB  1 
ATOM   6822  N N   . ASP C 3 103 ? 169.150 177.126 221.819 1.00 49.37  ? 147 ASP C N   1 
ATOM   6823  C CA  . ASP C 3 103 ? 168.710 177.467 220.472 1.00 49.37  ? 147 ASP C CA  1 
ATOM   6824  C C   . ASP C 3 103 ? 168.311 176.193 219.739 1.00 49.37  ? 147 ASP C C   1 
ATOM   6825  O O   . ASP C 3 103 ? 169.049 175.202 219.759 1.00 49.37  ? 147 ASP C O   1 
ATOM   6826  C CB  . ASP C 3 103 ? 169.814 178.204 219.718 1.00 49.37  ? 147 ASP C CB  1 
ATOM   6827  C CG  . ASP C 3 103 ? 169.318 178.837 218.432 1.00 49.37  ? 147 ASP C CG  1 
ATOM   6828  O OD1 . ASP C 3 103 ? 168.093 178.815 218.189 1.00 49.37  ? 147 ASP C OD1 1 
ATOM   6829  O OD2 . ASP C 3 103 ? 170.154 179.358 217.664 1.00 49.37  ? 147 ASP C OD2 1 
ATOM   6830  N N   . PHE C 3 104 ? 167.144 176.218 219.095 1.00 60.86  ? 148 PHE C N   1 
ATOM   6831  C CA  . PHE C 3 104 ? 166.641 175.021 218.431 1.00 60.86  ? 148 PHE C CA  1 
ATOM   6832  C C   . PHE C 3 104 ? 167.050 174.956 216.966 1.00 60.86  ? 148 PHE C C   1 
ATOM   6833  O O   . PHE C 3 104 ? 167.170 173.858 216.411 1.00 60.86  ? 148 PHE C O   1 
ATOM   6834  C CB  . PHE C 3 104 ? 165.119 174.958 218.554 1.00 60.86  ? 148 PHE C CB  1 
ATOM   6835  C CG  . PHE C 3 104 ? 164.529 173.658 218.098 1.00 60.86  ? 148 PHE C CG  1 
ATOM   6836  C CD1 . PHE C 3 104 ? 164.717 172.502 218.835 1.00 60.86  ? 148 PHE C CD1 1 
ATOM   6837  C CD2 . PHE C 3 104 ? 163.785 173.591 216.932 1.00 60.86  ? 148 PHE C CD2 1 
ATOM   6838  C CE1 . PHE C 3 104 ? 164.176 171.303 218.418 1.00 60.86  ? 148 PHE C CE1 1 
ATOM   6839  C CE2 . PHE C 3 104 ? 163.239 172.395 216.510 1.00 60.86  ? 148 PHE C CE2 1 
ATOM   6840  C CZ  . PHE C 3 104 ? 163.434 171.249 217.254 1.00 60.86  ? 148 PHE C CZ  1 
ATOM   6841  N N   . SER C 3 105 ? 167.268 176.105 216.325 1.00 58.82  ? 149 SER C N   1 
ATOM   6842  C CA  . SER C 3 105 ? 167.627 176.106 214.910 1.00 58.82  ? 149 SER C CA  1 
ATOM   6843  C C   . SER C 3 105 ? 169.108 175.817 214.705 1.00 58.82  ? 149 SER C C   1 
ATOM   6844  O O   . SER C 3 105 ? 169.477 175.082 213.782 1.00 58.82  ? 149 SER C O   1 
ATOM   6845  C CB  . SER C 3 105 ? 167.253 177.445 214.275 1.00 58.82  ? 149 SER C CB  1 
ATOM   6846  O OG  . SER C 3 105 ? 168.298 178.390 214.430 1.00 58.82  ? 149 SER C OG  1 
ATOM   6847  N N   . THR C 3 106 ? 169.967 176.386 215.548 1.00 57.86  ? 150 THR C N   1 
ATOM   6848  C CA  . THR C 3 106 ? 171.407 176.217 215.425 1.00 57.86  ? 150 THR C CA  1 
ATOM   6849  C C   . THR C 3 106 ? 171.966 175.175 216.388 1.00 57.86  ? 150 THR C C   1 
ATOM   6850  O O   . THR C 3 106 ? 173.147 174.824 216.281 1.00 57.86  ? 150 THR C O   1 
ATOM   6851  C CB  . THR C 3 106 ? 172.112 177.563 215.648 1.00 57.86  ? 150 THR C CB  1 
ATOM   6852  O OG1 . THR C 3 106 ? 171.336 178.609 215.051 1.00 57.86  ? 150 THR C OG1 1 
ATOM   6853  C CG2 . THR C 3 106 ? 173.493 177.568 215.005 1.00 57.86  ? 150 THR C CG2 1 
ATOM   6854  N N   . SER C 3 107 ? 171.146 174.665 217.309 1.00 45.02  ? 151 SER C N   1 
ATOM   6855  C CA  . SER C 3 107 ? 171.577 173.707 218.328 1.00 45.02  ? 151 SER C CA  1 
ATOM   6856  C C   . SER C 3 107 ? 172.710 174.292 219.174 1.00 45.02  ? 151 SER C C   1 
ATOM   6857  O O   . SER C 3 107 ? 173.830 173.778 219.217 1.00 45.02  ? 151 SER C O   1 
ATOM   6858  C CB  . SER C 3 107 ? 171.984 172.372 217.694 1.00 45.02  ? 151 SER C CB  1 
ATOM   6859  O OG  . SER C 3 107 ? 171.041 171.962 216.720 1.00 45.02  ? 151 SER C OG  1 
ATOM   6860  N N   . THR C 3 108 ? 172.391 175.392 219.853 1.00 36.73  ? 152 THR C N   1 
ATOM   6861  C CA  . THR C 3 108 ? 173.347 176.120 220.675 1.00 36.73  ? 152 THR C CA  1 
ATOM   6862  C C   . THR C 3 108 ? 172.746 176.340 222.055 1.00 36.73  ? 152 THR C C   1 
ATOM   6863  O O   . THR C 3 108 ? 171.577 176.719 222.172 1.00 36.73  ? 152 THR C O   1 
ATOM   6864  C CB  . THR C 3 108 ? 173.714 177.463 220.033 1.00 36.73  ? 152 THR C CB  1 
ATOM   6865  O OG1 . THR C 3 108 ? 174.169 177.243 218.692 1.00 36.73  ? 152 THR C OG1 1 
ATOM   6866  C CG2 . THR C 3 108 ? 174.811 178.153 220.824 1.00 36.73  ? 152 THR C CG2 1 
ATOM   6867  N N   . LEU C 3 109 ? 173.543 176.099 223.091 1.00 28.98  ? 153 LEU C N   1 
ATOM   6868  C CA  . LEU C 3 109 ? 173.088 176.240 224.465 1.00 28.98  ? 153 LEU C CA  1 
ATOM   6869  C C   . LEU C 3 109 ? 173.426 177.623 225.008 1.00 28.98  ? 153 LEU C C   1 
ATOM   6870  O O   . LEU C 3 109 ? 174.353 178.289 224.539 1.00 28.98  ? 153 LEU C O   1 
ATOM   6871  C CB  . LEU C 3 109 ? 173.716 175.167 225.354 1.00 28.98  ? 153 LEU C CB  1 
ATOM   6872  C CG  . LEU C 3 109 ? 173.606 173.722 224.863 1.00 28.98  ? 153 LEU C CG  1 
ATOM   6873  C CD1 . LEU C 3 109 ? 174.200 172.767 225.885 1.00 28.98  ? 153 LEU C CD1 1 
ATOM   6874  C CD2 . LEU C 3 109 ? 172.160 173.361 224.566 1.00 28.98  ? 153 LEU C CD2 1 
ATOM   6875  N N   . TYR C 3 110 ? 172.659 178.050 226.011 1.00 26.24  ? 154 TYR C N   1 
ATOM   6876  C CA  . TYR C 3 110 ? 172.869 179.327 226.679 1.00 26.24  ? 154 TYR C CA  1 
ATOM   6877  C C   . TYR C 3 110 ? 172.705 179.133 228.178 1.00 26.24  ? 154 TYR C C   1 
ATOM   6878  O O   . TYR C 3 110 ? 171.719 178.539 228.626 1.00 26.24  ? 154 TYR C O   1 
ATOM   6879  C CB  . TYR C 3 110 ? 171.887 180.390 226.175 1.00 26.24  ? 154 TYR C CB  1 
ATOM   6880  C CG  . TYR C 3 110 ? 171.919 180.596 224.678 1.00 26.24  ? 154 TYR C CG  1 
ATOM   6881  C CD1 . TYR C 3 110 ? 172.891 181.391 224.088 1.00 26.24  ? 154 TYR C CD1 1 
ATOM   6882  C CD2 . TYR C 3 110 ? 170.973 179.999 223.857 1.00 26.24  ? 154 TYR C CD2 1 
ATOM   6883  C CE1 . TYR C 3 110 ? 172.923 181.584 222.720 1.00 26.24  ? 154 TYR C CE1 1 
ATOM   6884  C CE2 . TYR C 3 110 ? 170.996 180.186 222.488 1.00 26.24  ? 154 TYR C CE2 1 
ATOM   6885  C CZ  . TYR C 3 110 ? 171.973 180.979 221.926 1.00 26.24  ? 154 TYR C CZ  1 
ATOM   6886  O OH  . TYR C 3 110 ? 172.001 181.168 220.563 1.00 26.24  ? 154 TYR C OH  1 
ATOM   6887  N N   . LEU C 3 111 ? 173.667 179.633 228.949 1.00 39.82  ? 155 LEU C N   1 
ATOM   6888  C CA  . LEU C 3 111 ? 173.658 179.509 230.399 1.00 39.82  ? 155 LEU C CA  1 
ATOM   6889  C C   . LEU C 3 111 ? 173.804 180.882 231.038 1.00 39.82  ? 155 LEU C C   1 
ATOM   6890  O O   . LEU C 3 111 ? 174.572 181.723 230.559 1.00 39.82  ? 155 LEU C O   1 
ATOM   6891  C CB  . LEU C 3 111 ? 174.781 178.585 230.881 1.00 39.82  ? 155 LEU C CB  1 
ATOM   6892  C CG  . LEU C 3 111 ? 174.736 178.183 232.356 1.00 39.82  ? 155 LEU C CG  1 
ATOM   6893  C CD1 . LEU C 3 111 ? 173.586 177.221 232.612 1.00 39.82  ? 155 LEU C CD1 1 
ATOM   6894  C CD2 . LEU C 3 111 ? 176.058 177.572 232.790 1.00 39.82  ? 155 LEU C CD2 1 
ATOM   6895  N N   . LYS C 3 112 ? 173.063 181.104 232.122 1.00 45.75  ? 156 LYS C N   1 
ATOM   6896  C CA  . LYS C 3 112 ? 173.108 182.353 232.871 1.00 45.75  ? 156 LYS C CA  1 
ATOM   6897  C C   . LYS C 3 112 ? 173.165 182.037 234.357 1.00 45.75  ? 156 LYS C C   1 
ATOM   6898  O O   . LYS C 3 112 ? 172.345 181.264 234.862 1.00 45.75  ? 156 LYS C O   1 
ATOM   6899  C CB  . LYS C 3 112 ? 171.891 183.232 232.563 1.00 45.75  ? 156 LYS C CB  1 
ATOM   6900  C CG  . LYS C 3 112 ? 171.810 183.702 231.121 1.00 45.75  ? 156 LYS C CG  1 
ATOM   6901  C CD  . LYS C 3 112 ? 170.595 184.585 230.895 1.00 45.75  ? 156 LYS C CD  1 
ATOM   6902  C CE  . LYS C 3 112 ? 170.493 185.019 229.442 1.00 45.75  ? 156 LYS C CE  1 
ATOM   6903  N NZ  . LYS C 3 112 ? 169.303 185.881 229.203 1.00 45.75  ? 156 LYS C NZ  1 
ATOM   6904  N N   . TRP C 3 113 ? 174.128 182.636 235.054 1.00 62.22  ? 157 TRP C N   1 
ATOM   6905  C CA  . TRP C 3 113 ? 174.300 182.395 236.478 1.00 62.22  ? 157 TRP C CA  1 
ATOM   6906  C C   . TRP C 3 113 ? 174.889 183.636 237.130 1.00 62.22  ? 157 TRP C C   1 
ATOM   6907  O O   . TRP C 3 113 ? 175.624 184.399 236.498 1.00 62.22  ? 157 TRP C O   1 
ATOM   6908  C CB  . TRP C 3 113 ? 175.200 181.182 236.738 1.00 62.22  ? 157 TRP C CB  1 
ATOM   6909  C CG  . TRP C 3 113 ? 176.642 181.429 236.421 1.00 62.22  ? 157 TRP C CG  1 
ATOM   6910  C CD1 . TRP C 3 113 ? 177.636 181.728 237.306 1.00 62.22  ? 157 TRP C CD1 1 
ATOM   6911  C CD2 . TRP C 3 113 ? 177.254 181.399 235.126 1.00 62.22  ? 157 TRP C CD2 1 
ATOM   6912  N NE1 . TRP C 3 113 ? 178.829 181.885 236.643 1.00 62.22  ? 157 TRP C NE1 1 
ATOM   6913  C CE2 . TRP C 3 113 ? 178.622 181.688 235.303 1.00 62.22  ? 157 TRP C CE2 1 
ATOM   6914  C CE3 . TRP C 3 113 ? 176.778 181.155 233.834 1.00 62.22  ? 157 TRP C CE3 1 
ATOM   6915  C CZ2 . TRP C 3 113 ? 179.518 181.740 234.238 1.00 62.22  ? 157 TRP C CZ2 1 
ATOM   6916  C CZ3 . TRP C 3 113 ? 177.670 181.207 232.777 1.00 62.22  ? 157 TRP C CZ3 1 
ATOM   6917  C CH2 . TRP C 3 113 ? 179.024 181.498 232.986 1.00 62.22  ? 157 TRP C CH2 1 
ATOM   6918  N N   . ASN C 3 114 ? 174.559 183.828 238.403 1.00 87.33  ? 158 ASN C N   1 
ATOM   6919  C CA  . ASN C 3 114 ? 175.033 184.965 239.177 1.00 87.33  ? 158 ASN C CA  1 
ATOM   6920  C C   . ASN C 3 114 ? 176.220 184.551 240.038 1.00 87.33  ? 158 ASN C C   1 
ATOM   6921  O O   . ASN C 3 114 ? 176.250 183.443 240.582 1.00 87.33  ? 158 ASN C O   1 
ATOM   6922  C CB  . ASN C 3 114 ? 173.917 185.528 240.059 1.00 87.33  ? 158 ASN C CB  1 
ATOM   6923  C CG  . ASN C 3 114 ? 174.318 186.812 240.757 1.00 87.33  ? 158 ASN C CG  1 
ATOM   6924  O OD1 . ASN C 3 114 ? 175.269 187.481 240.354 1.00 87.33  ? 158 ASN C OD1 1 
ATOM   6925  N ND2 . ASN C 3 114 ? 173.590 187.163 241.811 1.00 87.33  ? 158 ASN C ND2 1 
ATOM   6926  N N   . ASP C 3 115 ? 177.197 185.449 240.157 1.00 98.46  ? 159 ASP C N   1 
ATOM   6927  C CA  . ASP C 3 115 ? 178.408 185.162 240.914 1.00 98.46  ? 159 ASP C CA  1 
ATOM   6928  C C   . ASP C 3 115 ? 178.318 185.580 242.375 1.00 98.46  ? 159 ASP C C   1 
ATOM   6929  O O   . ASP C 3 115 ? 179.146 185.135 243.179 1.00 98.46  ? 159 ASP C O   1 
ATOM   6930  C CB  . ASP C 3 115 ? 179.612 185.855 240.268 1.00 98.46  ? 159 ASP C CB  1 
ATOM   6931  C CG  . ASP C 3 115 ? 179.398 187.344 240.080 1.00 98.46  ? 159 ASP C CG  1 
ATOM   6932  O OD1 . ASP C 3 115 ? 178.267 187.820 240.317 1.00 98.46  ? 159 ASP C OD1 1 
ATOM   6933  O OD2 . ASP C 3 115 ? 180.361 188.041 239.696 1.00 98.46  ? 159 ASP C OD2 1 
ATOM   6934  N N   . ARG C 3 116 ? 177.342 186.416 242.732 1.00 104.62 ? 160 ARG C N   1 
ATOM   6935  C CA  . ARG C 3 116 ? 177.174 186.918 244.096 1.00 104.62 ? 160 ARG C CA  1 
ATOM   6936  C C   . ARG C 3 116 ? 178.444 187.626 244.575 1.00 104.62 ? 160 ARG C C   1 
ATOM   6937  O O   . ARG C 3 116 ? 179.077 187.239 245.559 1.00 104.62 ? 160 ARG C O   1 
ATOM   6938  C CB  . ARG C 3 116 ? 176.773 185.789 245.052 1.00 104.62 ? 160 ARG C CB  1 
ATOM   6939  C CG  . ARG C 3 116 ? 175.400 185.202 244.777 1.00 104.62 ? 160 ARG C CG  1 
ATOM   6940  C CD  . ARG C 3 116 ? 174.306 186.234 244.990 1.00 104.62 ? 160 ARG C CD  1 
ATOM   6941  N NE  . ARG C 3 116 ? 172.984 185.700 244.676 1.00 104.62 ? 160 ARG C NE  1 
ATOM   6942  C CZ  . ARG C 3 116 ? 171.855 186.394 244.776 1.00 104.62 ? 160 ARG C CZ  1 
ATOM   6943  N NH1 . ARG C 3 116 ? 170.697 185.828 244.470 1.00 104.62 ? 160 ARG C NH1 1 
ATOM   6944  N NH2 . ARG C 3 116 ? 171.885 187.656 245.184 1.00 104.62 ? 160 ARG C NH2 1 
ATOM   6945  N N   . GLY C 3 117 ? 178.808 188.685 243.849 1.00 129.94 ? 161 GLY C N   1 
ATOM   6946  C CA  . GLY C 3 117 ? 180.008 189.436 244.173 1.00 129.94 ? 161 GLY C CA  1 
ATOM   6947  C C   . GLY C 3 117 ? 179.916 190.234 245.457 1.00 129.94 ? 161 GLY C C   1 
ATOM   6948  O O   . GLY C 3 117 ? 180.952 190.568 246.041 1.00 129.94 ? 161 GLY C O   1 
ATOM   6949  N N   . SER C 3 118 ? 178.700 190.546 245.911 1.00 140.81 ? 162 SER C N   1 
ATOM   6950  C CA  . SER C 3 118 ? 178.522 191.341 247.120 1.00 140.81 ? 162 SER C CA  1 
ATOM   6951  C C   . SER C 3 118 ? 178.943 190.604 248.384 1.00 140.81 ? 162 SER C C   1 
ATOM   6952  O O   . SER C 3 118 ? 179.076 191.242 249.434 1.00 140.81 ? 162 SER C O   1 
ATOM   6953  C CB  . SER C 3 118 ? 177.063 191.782 247.246 1.00 140.81 ? 162 SER C CB  1 
ATOM   6954  O OG  . SER C 3 118 ? 176.287 190.798 247.908 1.00 140.81 ? 162 SER C OG  1 
ATOM   6955  N N   . VAL C 3 119 ? 179.155 189.288 248.314 1.00 158.64 ? 163 VAL C N   1 
ATOM   6956  C CA  . VAL C 3 119 ? 179.561 188.544 249.502 1.00 158.64 ? 163 VAL C CA  1 
ATOM   6957  C C   . VAL C 3 119 ? 181.012 188.839 249.858 1.00 158.64 ? 163 VAL C C   1 
ATOM   6958  O O   . VAL C 3 119 ? 181.364 188.917 251.041 1.00 158.64 ? 163 VAL C O   1 
ATOM   6959  C CB  . VAL C 3 119 ? 179.326 187.037 249.292 1.00 158.64 ? 163 VAL C CB  1 
ATOM   6960  C CG1 . VAL C 3 119 ? 179.412 186.297 250.616 1.00 158.64 ? 163 VAL C CG1 1 
ATOM   6961  C CG2 . VAL C 3 119 ? 177.977 186.799 248.630 1.00 158.64 ? 163 VAL C CG2 1 
ATOM   6962  N N   . PHE C 3 120 ? 181.874 189.012 248.856 1.00 168.47 ? 164 PHE C N   1 
ATOM   6963  C CA  . PHE C 3 120 ? 183.283 189.285 249.088 1.00 168.47 ? 164 PHE C CA  1 
ATOM   6964  C C   . PHE C 3 120 ? 183.575 190.760 248.872 1.00 168.47 ? 164 PHE C C   1 
ATOM   6965  O O   . PHE C 3 120 ? 183.233 191.305 247.813 1.00 168.47 ? 164 PHE C O   1 
ATOM   6966  C CB  . PHE C 3 120 ? 184.159 188.439 248.158 1.00 168.47 ? 164 PHE C CB  1 
ATOM   6967  C CG  . PHE C 3 120 ? 184.085 186.966 248.433 1.00 168.47 ? 164 PHE C CG  1 
ATOM   6968  C CD1 . PHE C 3 120 ? 184.925 186.379 249.365 1.00 168.47 ? 164 PHE C CD1 1 
ATOM   6969  C CD2 . PHE C 3 120 ? 183.175 186.168 247.761 1.00 168.47 ? 164 PHE C CD2 1 
ATOM   6970  C CE1 . PHE C 3 120 ? 184.858 185.023 249.622 1.00 168.47 ? 164 PHE C CE1 1 
ATOM   6971  C CE2 . PHE C 3 120 ? 183.104 184.811 248.014 1.00 168.47 ? 164 PHE C CE2 1 
ATOM   6972  C CZ  . PHE C 3 120 ? 183.946 184.238 248.946 1.00 168.47 ? 164 PHE C CZ  1 
ATOM   6973  N N   . PRO C 3 121 ? 184.199 191.438 249.840 1.00 166.06 ? 165 PRO C N   1 
ATOM   6974  C CA  . PRO C 3 121 ? 184.484 192.869 249.665 1.00 166.06 ? 165 PRO C CA  1 
ATOM   6975  C C   . PRO C 3 121 ? 185.711 193.156 248.820 1.00 166.06 ? 165 PRO C C   1 
ATOM   6976  O O   . PRO C 3 121 ? 185.781 194.233 248.214 1.00 166.06 ? 165 PRO C O   1 
ATOM   6977  C CB  . PRO C 3 121 ? 184.683 193.360 251.104 1.00 166.06 ? 165 PRO C CB  1 
ATOM   6978  C CG  . PRO C 3 121 ? 185.229 192.165 251.818 1.00 166.06 ? 165 PRO C CG  1 
ATOM   6979  C CD  . PRO C 3 121 ? 184.610 190.948 251.168 1.00 166.06 ? 165 PRO C CD  1 
ATOM   6980  N N   . HIS C 3 122 ? 186.671 192.240 248.756 1.00 170.26 ? 166 HIS C N   1 
ATOM   6981  C CA  . HIS C 3 122 ? 187.904 192.444 248.013 1.00 170.26 ? 166 HIS C CA  1 
ATOM   6982  C C   . HIS C 3 122 ? 187.860 191.701 246.683 1.00 170.26 ? 166 HIS C C   1 
ATOM   6983  O O   . HIS C 3 122 ? 187.109 190.740 246.502 1.00 170.26 ? 166 HIS C O   1 
ATOM   6984  C CB  . HIS C 3 122 ? 189.112 191.980 248.832 1.00 170.26 ? 166 HIS C CB  1 
ATOM   6985  C CG  . HIS C 3 122 ? 189.308 192.742 250.105 1.00 170.26 ? 166 HIS C CG  1 
ATOM   6986  N ND1 . HIS C 3 122 ? 188.635 193.912 250.384 1.00 170.26 ? 166 HIS C ND1 1 
ATOM   6987  C CD2 . HIS C 3 122 ? 190.100 192.499 251.177 1.00 170.26 ? 166 HIS C CD2 1 
ATOM   6988  C CE1 . HIS C 3 122 ? 189.005 194.358 251.571 1.00 170.26 ? 166 HIS C CE1 1 
ATOM   6989  N NE2 . HIS C 3 122 ? 189.893 193.519 252.074 1.00 170.26 ? 166 HIS C NE2 1 
ATOM   6990  N N   . ARG C 3 123 ? 188.683 192.166 245.746 1.00 184.03 ? 167 ARG C N   1 
ATOM   6991  C CA  . ARG C 3 123 ? 188.759 191.536 244.436 1.00 184.03 ? 167 ARG C CA  1 
ATOM   6992  C C   . ARG C 3 123 ? 189.404 190.160 244.543 1.00 184.03 ? 167 ARG C C   1 
ATOM   6993  O O   . ARG C 3 123 ? 190.359 189.959 245.298 1.00 184.03 ? 167 ARG C O   1 
ATOM   6994  C CB  . ARG C 3 123 ? 189.553 192.413 243.469 1.00 184.03 ? 167 ARG C CB  1 
ATOM   6995  C CG  . ARG C 3 123 ? 188.889 193.739 243.136 1.00 184.03 ? 167 ARG C CG  1 
ATOM   6996  C CD  . ARG C 3 123 ? 189.696 194.511 242.105 1.00 184.03 ? 167 ARG C CD  1 
ATOM   6997  N NE  . ARG C 3 123 ? 189.042 195.756 241.714 1.00 184.03 ? 167 ARG C NE  1 
ATOM   6998  C CZ  . ARG C 3 123 ? 189.535 196.611 240.824 1.00 184.03 ? 167 ARG C CZ  1 
ATOM   6999  N NH1 . ARG C 3 123 ? 190.692 196.356 240.229 1.00 184.03 ? 167 ARG C NH1 1 
ATOM   7000  N NH2 . ARG C 3 123 ? 188.873 197.721 240.529 1.00 184.03 ? 167 ARG C NH2 1 
ATOM   7001  N N   . SER C 3 124 ? 188.873 189.208 243.780 1.00 191.92 ? 168 SER C N   1 
ATOM   7002  C CA  . SER C 3 124 ? 189.388 187.848 243.780 1.00 191.92 ? 168 SER C CA  1 
ATOM   7003  C C   . SER C 3 124 ? 189.124 187.216 242.422 1.00 191.92 ? 168 SER C C   1 
ATOM   7004  O O   . SER C 3 124 ? 188.061 187.420 241.831 1.00 191.92 ? 168 SER C O   1 
ATOM   7005  C CB  . SER C 3 124 ? 188.748 187.006 244.890 1.00 191.92 ? 168 SER C CB  1 
ATOM   7006  O OG  . SER C 3 124 ? 188.974 185.624 244.675 1.00 191.92 ? 168 SER C OG  1 
ATOM   7007  N N   . ASN C 3 125 ? 190.097 186.450 241.937 1.00 175.39 ? 169 ASN C N   1 
ATOM   7008  C CA  . ASN C 3 125 ? 189.954 185.756 240.666 1.00 175.39 ? 169 ASN C CA  1 
ATOM   7009  C C   . ASN C 3 125 ? 189.108 184.503 240.856 1.00 175.39 ? 169 ASN C C   1 
ATOM   7010  O O   . ASN C 3 125 ? 189.418 183.655 241.698 1.00 175.39 ? 169 ASN C O   1 
ATOM   7011  C CB  . ASN C 3 125 ? 191.325 185.393 240.097 1.00 175.39 ? 169 ASN C CB  1 
ATOM   7012  C CG  . ASN C 3 125 ? 191.241 184.807 238.702 1.00 175.39 ? 169 ASN C CG  1 
ATOM   7013  O OD1 . ASN C 3 125 ? 190.278 185.047 237.972 1.00 175.39 ? 169 ASN C OD1 1 
ATOM   7014  N ND2 . ASN C 3 125 ? 192.252 184.034 238.322 1.00 175.39 ? 169 ASN C ND2 1 
ATOM   7015  N N   . VAL C 3 126 ? 188.038 184.392 240.073 1.00 143.10 ? 170 VAL C N   1 
ATOM   7016  C CA  . VAL C 3 126 ? 187.107 183.272 240.152 1.00 143.10 ? 170 VAL C CA  1 
ATOM   7017  C C   . VAL C 3 126 ? 187.296 182.403 238.918 1.00 143.10 ? 170 VAL C C   1 
ATOM   7018  O O   . VAL C 3 126 ? 187.364 182.916 237.795 1.00 143.10 ? 170 VAL C O   1 
ATOM   7019  C CB  . VAL C 3 126 ? 185.651 183.757 240.266 1.00 143.10 ? 170 VAL C CB  1 
ATOM   7020  C CG1 . VAL C 3 126 ? 184.734 182.602 240.640 1.00 143.10 ? 170 VAL C CG1 1 
ATOM   7021  C CG2 . VAL C 3 126 ? 185.546 184.885 241.281 1.00 143.10 ? 170 VAL C CG2 1 
ATOM   7022  N N   . ILE C 3 127 ? 187.380 181.093 239.127 1.00 114.55 ? 171 ILE C N   1 
ATOM   7023  C CA  . ILE C 3 127 ? 187.558 180.126 238.051 1.00 114.55 ? 171 ILE C CA  1 
ATOM   7024  C C   . ILE C 3 127 ? 186.305 179.264 237.994 1.00 114.55 ? 171 ILE C C   1 
ATOM   7025  O O   . ILE C 3 127 ? 186.001 178.527 238.941 1.00 114.55 ? 171 ILE C O   1 
ATOM   7026  C CB  . ILE C 3 127 ? 188.814 179.268 238.255 1.00 114.55 ? 171 ILE C CB  1 
ATOM   7027  C CG1 . ILE C 3 127 ? 190.061 180.152 238.307 1.00 114.55 ? 171 ILE C CG1 1 
ATOM   7028  C CG2 . ILE C 3 127 ? 188.937 178.233 237.146 1.00 114.55 ? 171 ILE C CG2 1 
ATOM   7029  C CD1 . ILE C 3 127 ? 191.348 179.379 238.494 1.00 114.55 ? 171 ILE C CD1 1 
ATOM   7030  N N   . TRP C 3 128 ? 185.574 179.355 236.887 1.00 90.20  ? 172 TRP C N   1 
ATOM   7031  C CA  . TRP C 3 128 ? 184.367 178.572 236.675 1.00 90.20  ? 172 TRP C CA  1 
ATOM   7032  C C   . TRP C 3 128 ? 184.668 177.393 235.760 1.00 90.20  ? 172 TRP C C   1 
ATOM   7033  O O   . TRP C 3 128 ? 185.464 177.506 234.823 1.00 90.20  ? 172 TRP C O   1 
ATOM   7034  C CB  . TRP C 3 128 ? 183.255 179.431 236.070 1.00 90.20  ? 172 TRP C CB  1 
ATOM   7035  C CG  . TRP C 3 128 ? 182.888 180.617 236.907 1.00 90.20  ? 172 TRP C CG  1 
ATOM   7036  C CD1 . TRP C 3 128 ? 183.491 181.840 236.904 1.00 90.20  ? 172 TRP C CD1 1 
ATOM   7037  C CD2 . TRP C 3 128 ? 181.829 180.694 237.869 1.00 90.20  ? 172 TRP C CD2 1 
ATOM   7038  N NE1 . TRP C 3 128 ? 182.875 182.674 237.805 1.00 90.20  ? 172 TRP C NE1 1 
ATOM   7039  C CE2 . TRP C 3 128 ? 181.852 181.994 238.411 1.00 90.20  ? 172 TRP C CE2 1 
ATOM   7040  C CE3 . TRP C 3 128 ? 180.865 179.790 238.326 1.00 90.20  ? 172 TRP C CE3 1 
ATOM   7041  C CZ2 . TRP C 3 128 ? 180.949 182.412 239.386 1.00 90.20  ? 172 TRP C CZ2 1 
ATOM   7042  C CZ3 . TRP C 3 128 ? 179.970 180.207 239.294 1.00 90.20  ? 172 TRP C CZ3 1 
ATOM   7043  C CH2 . TRP C 3 128 ? 180.018 181.506 239.813 1.00 90.20  ? 172 TRP C CH2 1 
ATOM   7044  N N   . GLU C 3 129 ? 184.026 176.260 236.037 1.00 81.31  ? 173 GLU C N   1 
ATOM   7045  C CA  . GLU C 3 129 ? 184.202 175.039 235.256 1.00 81.31  ? 173 GLU C CA  1 
ATOM   7046  C C   . GLU C 3 129 ? 182.829 174.545 234.823 1.00 81.31  ? 173 GLU C C   1 
ATOM   7047  O O   . GLU C 3 129 ? 182.084 173.984 235.633 1.00 81.31  ? 173 GLU C O   1 
ATOM   7048  C CB  . GLU C 3 129 ? 184.937 173.969 236.064 1.00 81.31  ? 173 GLU C CB  1 
ATOM   7049  C CG  . GLU C 3 129 ? 186.447 174.144 236.105 1.00 81.31  ? 173 GLU C CG  1 
ATOM   7050  C CD  . GLU C 3 129 ? 187.149 173.433 234.966 1.00 81.31  ? 173 GLU C CD  1 
ATOM   7051  O OE1 . GLU C 3 129 ? 186.471 173.056 233.987 1.00 81.31  ? 173 GLU C OE1 1 
ATOM   7052  O OE2 . GLU C 3 129 ? 188.381 173.245 235.052 1.00 81.31  ? 173 GLU C OE2 1 
ATOM   7053  N N   . ILE C 3 130 ? 182.497 174.752 233.553 1.00 62.47  ? 174 ILE C N   1 
ATOM   7054  C CA  . ILE C 3 130 ? 181.218 174.319 233.004 1.00 62.47  ? 174 ILE C CA  1 
ATOM   7055  C C   . ILE C 3 130 ? 181.378 172.914 232.437 1.00 62.47  ? 174 ILE C C   1 
ATOM   7056  O O   . ILE C 3 130 ? 182.379 172.607 231.777 1.00 62.47  ? 174 ILE C O   1 
ATOM   7057  C CB  . ILE C 3 130 ? 180.717 175.303 231.932 1.00 62.47  ? 174 ILE C CB  1 
ATOM   7058  C CG1 . ILE C 3 130 ? 179.410 174.806 231.310 1.00 62.47  ? 174 ILE C CG1 1 
ATOM   7059  C CG2 . ILE C 3 130 ? 181.775 175.536 230.862 1.00 62.47  ? 174 ILE C CG2 1 
ATOM   7060  C CD1 . ILE C 3 130 ? 178.280 174.667 232.302 1.00 62.47  ? 174 ILE C CD1 1 
ATOM   7061  N N   . LYS C 3 131 ? 180.400 172.053 232.708 1.00 49.38  ? 175 LYS C N   1 
ATOM   7062  C CA  . LYS C 3 131 ? 180.415 170.668 232.254 1.00 49.38  ? 175 LYS C CA  1 
ATOM   7063  C C   . LYS C 3 131 ? 179.127 170.384 231.496 1.00 49.38  ? 175 LYS C C   1 
ATOM   7064  O O   . LYS C 3 131 ? 178.032 170.552 232.043 1.00 49.38  ? 175 LYS C O   1 
ATOM   7065  C CB  . LYS C 3 131 ? 180.573 169.705 233.432 1.00 49.38  ? 175 LYS C CB  1 
ATOM   7066  C CG  . LYS C 3 131 ? 180.565 168.239 233.038 1.00 49.38  ? 175 LYS C CG  1 
ATOM   7067  C CD  . LYS C 3 131 ? 181.084 167.361 234.164 1.00 49.38  ? 175 LYS C CD  1 
ATOM   7068  C CE  . LYS C 3 131 ? 180.274 167.553 235.434 1.00 49.38  ? 175 LYS C CE  1 
ATOM   7069  N NZ  . LYS C 3 131 ? 180.831 166.769 236.571 1.00 49.38  ? 175 LYS C NZ  1 
ATOM   7070  N N   . VAL C 3 132 ? 179.259 169.954 230.244 1.00 32.40  ? 176 VAL C N   1 
ATOM   7071  C CA  . VAL C 3 132 ? 178.122 169.627 229.393 1.00 32.40  ? 176 VAL C CA  1 
ATOM   7072  C C   . VAL C 3 132 ? 177.978 168.114 229.340 1.00 32.40  ? 176 VAL C C   1 
ATOM   7073  O O   . VAL C 3 132 ? 178.955 167.398 229.088 1.00 32.40  ? 176 VAL C O   1 
ATOM   7074  C CB  . VAL C 3 132 ? 178.294 170.213 227.981 1.00 32.40  ? 176 VAL C CB  1 
ATOM   7075  C CG1 . VAL C 3 132 ? 177.099 169.861 227.111 1.00 32.40  ? 176 VAL C CG1 1 
ATOM   7076  C CG2 . VAL C 3 132 ? 178.484 171.719 228.053 1.00 32.40  ? 176 VAL C CG2 1 
ATOM   7077  N N   . LEU C 3 133 ? 176.763 167.626 229.573 1.00 31.65  ? 177 LEU C N   1 
ATOM   7078  C CA  . LEU C 3 133 ? 176.481 166.201 229.578 1.00 31.65  ? 177 LEU C CA  1 
ATOM   7079  C C   . LEU C 3 133 ? 175.357 165.883 228.602 1.00 31.65  ? 177 LEU C C   1 
ATOM   7080  O O   . LEU C 3 133 ? 174.600 166.761 228.180 1.00 31.65  ? 177 LEU C O   1 
ATOM   7081  C CB  . LEU C 3 133 ? 176.102 165.713 230.982 1.00 31.65  ? 177 LEU C CB  1 
ATOM   7082  C CG  . LEU C 3 133 ? 177.095 166.015 232.105 1.00 31.65  ? 177 LEU C CG  1 
ATOM   7083  C CD1 . LEU C 3 133 ? 176.574 165.495 233.434 1.00 31.65  ? 177 LEU C CD1 1 
ATOM   7084  C CD2 . LEU C 3 133 ? 178.453 165.416 231.788 1.00 31.65  ? 177 LEU C CD2 1 
ATOM   7085  N N   . ARG C 3 134 ? 175.265 164.606 228.247 1.00 32.95  ? 178 ARG C N   1 
ATOM   7086  C CA  . ARG C 3 134 ? 174.212 164.083 227.386 1.00 32.95  ? 178 ARG C CA  1 
ATOM   7087  C C   . ARG C 3 134 ? 174.162 162.575 227.599 1.00 32.95  ? 178 ARG C C   1 
ATOM   7088  O O   . ARG C 3 134 ? 174.817 162.044 228.503 1.00 32.95  ? 178 ARG C O   1 
ATOM   7089  C CB  . ARG C 3 134 ? 174.459 164.455 225.921 1.00 32.95  ? 178 ARG C CB  1 
ATOM   7090  C CG  . ARG C 3 134 ? 175.716 163.842 225.333 1.00 32.95  ? 178 ARG C CG  1 
ATOM   7091  C CD  . ARG C 3 134 ? 175.572 163.620 223.838 1.00 32.95  ? 178 ARG C CD  1 
ATOM   7092  N NE  . ARG C 3 134 ? 175.265 164.858 223.131 1.00 32.95  ? 178 ARG C NE  1 
ATOM   7093  C CZ  . ARG C 3 134 ? 175.069 164.940 221.820 1.00 32.95  ? 178 ARG C CZ  1 
ATOM   7094  N NH1 . ARG C 3 134 ? 174.794 166.110 221.261 1.00 32.95  ? 178 ARG C NH1 1 
ATOM   7095  N NH2 . ARG C 3 134 ? 175.149 163.852 221.067 1.00 32.95  ? 178 ARG C NH2 1 
ATOM   7096  N N   . LYS C 3 135 ? 173.386 161.877 226.764 1.00 60.32  ? 179 LYS C N   1 
ATOM   7097  C CA  . LYS C 3 135 ? 173.284 160.419 226.825 1.00 60.32  ? 179 LYS C CA  1 
ATOM   7098  C C   . LYS C 3 135 ? 172.832 159.976 228.221 1.00 60.32  ? 179 LYS C C   1 
ATOM   7099  O O   . LYS C 3 135 ? 173.591 159.402 229.005 1.00 60.32  ? 179 LYS C O   1 
ATOM   7100  C CB  . LYS C 3 135 ? 174.607 159.755 226.426 1.00 60.32  ? 179 LYS C CB  1 
ATOM   7101  C CG  . LYS C 3 135 ? 174.484 158.289 226.046 1.00 60.32  ? 179 LYS C CG  1 
ATOM   7102  C CD  . LYS C 3 135 ? 173.646 158.111 224.792 1.00 60.32  ? 179 LYS C CD  1 
ATOM   7103  C CE  . LYS C 3 135 ? 173.588 156.651 224.373 1.00 60.32  ? 179 LYS C CE  1 
ATOM   7104  N NZ  . LYS C 3 135 ? 172.985 155.795 225.431 1.00 60.32  ? 179 LYS C NZ  1 
ATOM   7105  N N   . GLU C 3 136 ? 171.563 160.282 228.503 1.00 61.51  ? 180 GLU C N   1 
ATOM   7106  C CA  . GLU C 3 136 ? 170.971 160.260 229.840 1.00 61.51  ? 180 GLU C CA  1 
ATOM   7107  C C   . GLU C 3 136 ? 171.426 159.087 230.701 1.00 61.51  ? 180 GLU C C   1 
ATOM   7108  O O   . GLU C 3 136 ? 171.467 159.203 231.931 1.00 61.51  ? 180 GLU C O   1 
ATOM   7109  C CB  . GLU C 3 136 ? 169.444 160.248 229.721 1.00 61.51  ? 180 GLU C CB  1 
ATOM   7110  C CG  . GLU C 3 136 ? 168.702 160.398 231.040 1.00 61.51  ? 180 GLU C CG  1 
ATOM   7111  C CD  . GLU C 3 136 ? 168.293 159.064 231.634 1.00 61.51  ? 180 GLU C CD  1 
ATOM   7112  O OE1 . GLU C 3 136 ? 168.439 158.035 230.941 1.00 61.51  ? 180 GLU C OE1 1 
ATOM   7113  O OE2 . GLU C 3 136 ? 167.828 159.044 232.792 1.00 61.51  ? 180 GLU C OE2 1 
ATOM   7114  N N   . SER C 3 137 ? 171.764 157.956 230.081 1.00 76.38  ? 181 SER C N   1 
ATOM   7115  C CA  . SER C 3 137 ? 172.368 156.861 230.829 1.00 76.38  ? 181 SER C CA  1 
ATOM   7116  C C   . SER C 3 137 ? 173.654 157.331 231.501 1.00 76.38  ? 181 SER C C   1 
ATOM   7117  O O   . SER C 3 137 ? 173.713 157.421 232.732 1.00 76.38  ? 181 SER C O   1 
ATOM   7118  C CB  . SER C 3 137 ? 172.646 155.670 229.909 1.00 76.38  ? 181 SER C CB  1 
ATOM   7119  O OG  . SER C 3 137 ? 171.442 155.021 229.540 1.00 76.38  ? 181 SER C OG  1 
ATOM   7120  N N   . MET C 3 138 ? 174.674 157.651 230.704 1.00 86.16  ? 182 MET C N   1 
ATOM   7121  C CA  . MET C 3 138 ? 175.910 158.243 231.203 1.00 86.16  ? 182 MET C CA  1 
ATOM   7122  C C   . MET C 3 138 ? 176.775 158.662 230.023 1.00 86.16  ? 182 MET C C   1 
ATOM   7123  O O   . MET C 3 138 ? 176.923 157.900 229.065 1.00 86.16  ? 182 MET C O   1 
ATOM   7124  C CB  . MET C 3 138 ? 176.687 157.264 232.094 1.00 86.16  ? 182 MET C CB  1 
ATOM   7125  C CG  . MET C 3 138 ? 177.815 157.894 232.908 1.00 86.16  ? 182 MET C CG  1 
ATOM   7126  S SD  . MET C 3 138 ? 177.259 158.959 234.259 1.00 86.16  ? 182 MET C SD  1 
ATOM   7127  C CE  . MET C 3 138 ? 177.230 160.572 233.477 1.00 86.16  ? 182 MET C CE  1 
ATOM   7128  N N   . GLU C 3 139 ? 177.352 159.861 230.110 1.00 53.87  ? 183 GLU C N   1 
ATOM   7129  C CA  . GLU C 3 139 ? 178.356 160.336 229.162 1.00 53.87  ? 183 GLU C CA  1 
ATOM   7130  C C   . GLU C 3 139 ? 178.865 161.695 229.621 1.00 53.87  ? 183 GLU C C   1 
ATOM   7131  O O   . GLU C 3 139 ? 178.225 162.381 230.424 1.00 53.87  ? 183 GLU C O   1 
ATOM   7132  C CB  . GLU C 3 139 ? 177.817 160.444 227.731 1.00 53.87  ? 183 GLU C CB  1 
ATOM   7133  C CG  . GLU C 3 139 ? 178.865 160.154 226.664 1.00 53.87  ? 183 GLU C CG  1 
ATOM   7134  C CD  . GLU C 3 139 ? 178.385 160.472 225.261 1.00 53.87  ? 183 GLU C CD  1 
ATOM   7135  O OE1 . GLU C 3 139 ? 177.255 160.980 225.117 1.00 53.87  ? 183 GLU C OE1 1 
ATOM   7136  O OE2 . GLU C 3 139 ? 179.141 160.213 224.302 1.00 53.87  ? 183 GLU C OE2 1 
ATOM   7137  N N   . LEU C 3 140 ? 180.028 162.072 229.095 1.00 35.91  ? 184 LEU C N   1 
ATOM   7138  C CA  . LEU C 3 140 ? 180.634 163.375 229.332 1.00 35.91  ? 184 LEU C CA  1 
ATOM   7139  C C   . LEU C 3 140 ? 181.230 163.861 228.021 1.00 35.91  ? 184 LEU C C   1 
ATOM   7140  O O   . LEU C 3 140 ? 181.905 163.094 227.328 1.00 35.91  ? 184 LEU C O   1 
ATOM   7141  C CB  . LEU C 3 140 ? 181.711 163.297 230.421 1.00 35.91  ? 184 LEU C CB  1 
ATOM   7142  C CG  . LEU C 3 140 ? 182.719 164.445 230.514 1.00 35.91  ? 184 LEU C CG  1 
ATOM   7143  C CD1 . LEU C 3 140 ? 182.020 165.762 230.803 1.00 35.91  ? 184 LEU C CD1 1 
ATOM   7144  C CD2 . LEU C 3 140 ? 183.767 164.147 231.575 1.00 35.91  ? 184 LEU C CD2 1 
ATOM   7145  N N   . VAL C 3 141 ? 180.983 165.125 227.679 1.00 31.40  ? 185 VAL C N   1 
ATOM   7146  C CA  . VAL C 3 141 ? 181.379 165.637 226.371 1.00 31.40  ? 185 VAL C CA  1 
ATOM   7147  C C   . VAL C 3 141 ? 182.337 166.814 226.506 1.00 31.40  ? 185 VAL C C   1 
ATOM   7148  O O   . VAL C 3 141 ? 183.486 166.745 226.056 1.00 31.40  ? 185 VAL C O   1 
ATOM   7149  C CB  . VAL C 3 141 ? 180.145 166.038 225.542 1.00 31.40  ? 185 VAL C CB  1 
ATOM   7150  C CG1 . VAL C 3 141 ? 180.574 166.617 224.203 1.00 31.40  ? 185 VAL C CG1 1 
ATOM   7151  C CG2 . VAL C 3 141 ? 179.229 164.843 225.342 1.00 31.40  ? 185 VAL C CG2 1 
ATOM   7152  N N   . LYS C 3 142 ? 181.876 167.899 227.122 1.00 39.71  ? 186 LYS C N   1 
ATOM   7153  C CA  . LYS C 3 142 ? 182.616 169.152 227.144 1.00 39.71  ? 186 LYS C CA  1 
ATOM   7154  C C   . LYS C 3 142 ? 182.990 169.536 228.569 1.00 39.71  ? 186 LYS C C   1 
ATOM   7155  O O   . LYS C 3 142 ? 182.271 169.230 229.526 1.00 39.71  ? 186 LYS C O   1 
ATOM   7156  C CB  . LYS C 3 142 ? 181.802 170.283 226.503 1.00 39.71  ? 186 LYS C CB  1 
ATOM   7157  C CG  . LYS C 3 142 ? 182.643 171.427 225.960 1.00 39.71  ? 186 LYS C CG  1 
ATOM   7158  C CD  . LYS C 3 142 ? 183.471 170.984 224.766 1.00 39.71  ? 186 LYS C CD  1 
ATOM   7159  C CE  . LYS C 3 142 ? 184.209 172.156 224.141 1.00 39.71  ? 186 LYS C CE  1 
ATOM   7160  N NZ  . LYS C 3 142 ? 185.005 171.741 222.952 1.00 39.71  ? 186 LYS C NZ  1 
ATOM   7161  N N   . LEU C 3 143 ? 184.131 170.215 228.696 1.00 50.43  ? 187 LEU C N   1 
ATOM   7162  C CA  . LEU C 3 143 ? 184.590 170.740 229.981 1.00 50.43  ? 187 LEU C CA  1 
ATOM   7163  C C   . LEU C 3 143 ? 185.503 171.925 229.678 1.00 50.43  ? 187 LEU C C   1 
ATOM   7164  O O   . LEU C 3 143 ? 186.665 171.736 229.307 1.00 50.43  ? 187 LEU C O   1 
ATOM   7165  C CB  . LEU C 3 143 ? 185.307 169.670 230.793 1.00 50.43  ? 187 LEU C CB  1 
ATOM   7166  C CG  . LEU C 3 143 ? 185.687 170.058 232.223 1.00 50.43  ? 187 LEU C CG  1 
ATOM   7167  C CD1 . LEU C 3 143 ? 184.441 170.292 233.063 1.00 50.43  ? 187 LEU C CD1 1 
ATOM   7168  C CD2 . LEU C 3 143 ? 186.569 168.991 232.853 1.00 50.43  ? 187 LEU C CD2 1 
ATOM   7169  N N   . VAL C 3 144 ? 184.973 173.135 229.837 1.00 78.06  ? 188 VAL C N   1 
ATOM   7170  C CA  . VAL C 3 144 ? 185.681 174.364 229.497 1.00 78.06  ? 188 VAL C CA  1 
ATOM   7171  C C   . VAL C 3 144 ? 185.833 175.206 230.757 1.00 78.06  ? 188 VAL C C   1 
ATOM   7172  O O   . VAL C 3 144 ? 184.913 175.282 231.579 1.00 78.06  ? 188 VAL C O   1 
ATOM   7173  C CB  . VAL C 3 144 ? 184.941 175.149 228.392 1.00 78.06  ? 188 VAL C CB  1 
ATOM   7174  C CG1 . VAL C 3 144 ? 185.610 176.492 228.133 1.00 78.06  ? 188 VAL C CG1 1 
ATOM   7175  C CG2 . VAL C 3 144 ? 184.871 174.326 227.114 1.00 78.06  ? 188 VAL C CG2 1 
ATOM   7176  N N   . THR C 3 145 ? 186.998 175.831 230.908 1.00 95.82  ? 189 THR C N   1 
ATOM   7177  C CA  . THR C 3 145 ? 187.271 176.698 232.045 1.00 95.82  ? 189 THR C CA  1 
ATOM   7178  C C   . THR C 3 145 ? 186.861 178.130 231.726 1.00 95.82  ? 189 THR C C   1 
ATOM   7179  O O   . THR C 3 145 ? 186.979 178.584 230.584 1.00 95.82  ? 189 THR C O   1 
ATOM   7180  C CB  . THR C 3 145 ? 188.754 176.653 232.417 1.00 95.82  ? 189 THR C CB  1 
ATOM   7181  O OG1 . THR C 3 145 ? 189.526 177.271 231.380 1.00 95.82  ? 189 THR C OG1 1 
ATOM   7182  C CG2 . THR C 3 145 ? 189.215 175.215 232.591 1.00 95.82  ? 189 THR C CG2 1 
ATOM   7183  N N   . HIS C 3 146 ? 186.379 178.839 232.745 1.00 96.54  ? 190 HIS C N   1 
ATOM   7184  C CA  . HIS C 3 146 ? 185.953 180.227 232.597 1.00 96.54  ? 190 HIS C CA  1 
ATOM   7185  C C   . HIS C 3 146 ? 186.453 181.020 233.793 1.00 96.54  ? 190 HIS C C   1 
ATOM   7186  O O   . HIS C 3 146 ? 186.147 180.676 234.939 1.00 96.54  ? 190 HIS C O   1 
ATOM   7187  C CB  . HIS C 3 146 ? 184.430 180.332 232.480 1.00 96.54  ? 190 HIS C CB  1 
ATOM   7188  C CG  . HIS C 3 146 ? 183.956 181.640 231.929 1.00 96.54  ? 190 HIS C CG  1 
ATOM   7189  N ND1 . HIS C 3 146 ? 183.735 182.746 232.721 1.00 96.54  ? 190 HIS C ND1 1 
ATOM   7190  C CD2 . HIS C 3 146 ? 183.659 182.019 230.663 1.00 96.54  ? 190 HIS C CD2 1 
ATOM   7191  C CE1 . HIS C 3 146 ? 183.324 183.750 231.967 1.00 96.54  ? 190 HIS C CE1 1 
ATOM   7192  N NE2 . HIS C 3 146 ? 183.268 183.335 230.714 1.00 96.54  ? 190 HIS C NE2 1 
ATOM   7193  N N   . ASN C 3 147 ? 187.217 182.076 233.530 1.00 110.04 ? 191 ASN C N   1 
ATOM   7194  C CA  . ASN C 3 147 ? 187.782 182.924 234.570 1.00 110.04 ? 191 ASN C CA  1 
ATOM   7195  C C   . ASN C 3 147 ? 187.067 184.267 234.580 1.00 110.04 ? 191 ASN C C   1 
ATOM   7196  O O   . ASN C 3 147 ? 186.899 184.894 233.529 1.00 110.04 ? 191 ASN C O   1 
ATOM   7197  C CB  . ASN C 3 147 ? 189.284 183.124 234.356 1.00 110.04 ? 191 ASN C CB  1 
ATOM   7198  C CG  . ASN C 3 147 ? 190.067 181.833 234.482 1.00 110.04 ? 191 ASN C CG  1 
ATOM   7199  O OD1 . ASN C 3 147 ? 189.498 180.742 234.446 1.00 110.04 ? 191 ASN C OD1 1 
ATOM   7200  N ND2 . ASN C 3 147 ? 191.382 181.950 234.631 1.00 110.04 ? 191 ASN C ND2 1 
ATOM   7201  N N   . THR C 3 148 ? 186.648 184.703 235.766 1.00 126.01 ? 192 THR C N   1 
ATOM   7202  C CA  . THR C 3 148 ? 185.982 185.985 235.952 1.00 126.01 ? 192 THR C CA  1 
ATOM   7203  C C   . THR C 3 148 ? 186.712 186.775 237.032 1.00 126.01 ? 192 THR C C   1 
ATOM   7204  O O   . THR C 3 148 ? 187.678 186.301 237.636 1.00 126.01 ? 192 THR C O   1 
ATOM   7205  C CB  . THR C 3 148 ? 184.503 185.801 236.321 1.00 126.01 ? 192 THR C CB  1 
ATOM   7206  O OG1 . THR C 3 148 ? 184.401 185.042 237.532 1.00 126.01 ? 192 THR C OG1 1 
ATOM   7207  C CG2 . THR C 3 148 ? 183.760 185.078 235.210 1.00 126.01 ? 192 THR C CG2 1 
ATOM   7208  N N   . THR C 3 149 ? 186.240 187.997 237.274 1.00 146.22 ? 193 THR C N   1 
ATOM   7209  C CA  . THR C 3 149 ? 186.838 188.891 238.256 1.00 146.22 ? 193 THR C CA  1 
ATOM   7210  C C   . THR C 3 149 ? 185.743 189.484 239.128 1.00 146.22 ? 193 THR C C   1 
ATOM   7211  O O   . THR C 3 149 ? 184.772 190.048 238.614 1.00 146.22 ? 193 THR C O   1 
ATOM   7212  C CB  . THR C 3 149 ? 187.636 190.010 237.578 1.00 146.22 ? 193 THR C CB  1 
ATOM   7213  O OG1 . THR C 3 149 ? 188.666 189.439 236.762 1.00 146.22 ? 193 THR C OG1 1 
ATOM   7214  C CG2 . THR C 3 149 ? 188.268 190.920 238.620 1.00 146.22 ? 193 THR C CG2 1 
ATOM   7215  N N   . LEU C 3 150 ? 185.902 189.356 240.442 1.00 157.88 ? 194 LEU C N   1 
ATOM   7216  C CA  . LEU C 3 150 ? 184.930 189.872 241.395 1.00 157.88 ? 194 LEU C CA  1 
ATOM   7217  C C   . LEU C 3 150 ? 185.271 191.311 241.762 1.00 157.88 ? 194 LEU C C   1 
ATOM   7218  O O   . LEU C 3 150 ? 186.442 191.661 241.932 1.00 157.88 ? 194 LEU C O   1 
ATOM   7219  C CB  . LEU C 3 150 ? 184.891 188.989 242.645 1.00 157.88 ? 194 LEU C CB  1 
ATOM   7220  C CG  . LEU C 3 150 ? 183.805 189.228 243.698 1.00 157.88 ? 194 LEU C CG  1 
ATOM   7221  C CD1 . LEU C 3 150 ? 183.424 187.913 244.353 1.00 157.88 ? 194 LEU C CD1 1 
ATOM   7222  C CD2 . LEU C 3 150 ? 184.280 190.210 244.755 1.00 157.88 ? 194 LEU C CD2 1 
ATOM   7223  N N   . ASN C 3 151 ? 184.233 192.144 241.883 1.00 153.25 ? 195 ASN C N   1 
ATOM   7224  C CA  . ASN C 3 151 ? 184.412 193.559 242.188 1.00 153.25 ? 195 ASN C CA  1 
ATOM   7225  C C   . ASN C 3 151 ? 183.429 194.036 243.252 1.00 153.25 ? 195 ASN C C   1 
ATOM   7226  O O   . ASN C 3 151 ? 183.027 195.205 243.251 1.00 153.25 ? 195 ASN C O   1 
ATOM   7227  C CB  . ASN C 3 151 ? 184.278 194.416 240.924 1.00 153.25 ? 195 ASN C CB  1 
ATOM   7228  C CG  . ASN C 3 151 ? 182.961 194.191 240.195 1.00 153.25 ? 195 ASN C CG  1 
ATOM   7229  O OD1 . ASN C 3 151 ? 182.029 193.590 240.731 1.00 153.25 ? 195 ASN C OD1 1 
ATOM   7230  N ND2 . ASN C 3 151 ? 182.880 194.681 238.964 1.00 153.25 ? 195 ASN C ND2 1 
ATOM   7231  N N   . GLY C 3 152 ? 183.033 193.151 244.164 1.00 143.27 ? 196 GLY C N   1 
ATOM   7232  C CA  . GLY C 3 152 ? 182.093 193.512 245.205 1.00 143.27 ? 196 GLY C CA  1 
ATOM   7233  C C   . GLY C 3 152 ? 180.670 193.722 244.744 1.00 143.27 ? 196 GLY C C   1 
ATOM   7234  O O   . GLY C 3 152 ? 179.845 194.196 245.531 1.00 143.27 ? 196 GLY C O   1 
ATOM   7235  N N   . LYS C 3 153 ? 180.353 193.387 243.495 1.00 136.55 ? 197 LYS C N   1 
ATOM   7236  C CA  . LYS C 3 153 ? 179.014 193.569 242.956 1.00 136.55 ? 197 LYS C CA  1 
ATOM   7237  C C   . LYS C 3 153 ? 178.597 192.317 242.199 1.00 136.55 ? 197 LYS C C   1 
ATOM   7238  O O   . LYS C 3 153 ? 179.421 191.681 241.536 1.00 136.55 ? 197 LYS C O   1 
ATOM   7239  C CB  . LYS C 3 153 ? 178.943 194.791 242.031 1.00 136.55 ? 197 LYS C CB  1 
ATOM   7240  C CG  . LYS C 3 153 ? 179.139 196.119 242.743 1.00 136.55 ? 197 LYS C CG  1 
ATOM   7241  C CD  . LYS C 3 153 ? 178.955 197.289 241.792 1.00 136.55 ? 197 LYS C CD  1 
ATOM   7242  C CE  . LYS C 3 153 ? 179.113 198.615 242.517 1.00 136.55 ? 197 LYS C CE  1 
ATOM   7243  N NZ  . LYS C 3 153 ? 178.898 199.774 241.607 1.00 136.55 ? 197 LYS C NZ  1 
ATOM   7244  N N   . ASP C 3 154 ? 177.316 191.973 242.302 1.00 112.97 ? 198 ASP C N   1 
ATOM   7245  C CA  . ASP C 3 154 ? 176.792 190.791 241.629 1.00 112.97 ? 198 ASP C CA  1 
ATOM   7246  C C   . ASP C 3 154 ? 176.691 191.049 240.130 1.00 112.97 ? 198 ASP C C   1 
ATOM   7247  O O   . ASP C 3 154 ? 175.988 191.968 239.696 1.00 112.97 ? 198 ASP C O   1 
ATOM   7248  C CB  . ASP C 3 154 ? 175.428 190.419 242.203 1.00 112.97 ? 198 ASP C CB  1 
ATOM   7249  C CG  . ASP C 3 154 ? 175.453 190.267 243.710 1.00 112.97 ? 198 ASP C CG  1 
ATOM   7250  O OD1 . ASP C 3 154 ? 176.536 190.437 244.307 1.00 112.97 ? 198 ASP C OD1 1 
ATOM   7251  O OD2 . ASP C 3 154 ? 174.390 189.977 244.298 1.00 112.97 ? 198 ASP C OD2 1 
ATOM   7252  N N   . THR C 3 155 ? 177.392 190.239 239.341 1.00 107.68 ? 199 THR C N   1 
ATOM   7253  C CA  . THR C 3 155 ? 177.409 190.368 237.891 1.00 107.68 ? 199 THR C CA  1 
ATOM   7254  C C   . THR C 3 155 ? 176.867 189.095 237.255 1.00 107.68 ? 199 THR C C   1 
ATOM   7255  O O   . THR C 3 155 ? 177.248 187.986 237.641 1.00 107.68 ? 199 THR C O   1 
ATOM   7256  C CB  . THR C 3 155 ? 178.825 190.646 237.375 1.00 107.68 ? 199 THR C CB  1 
ATOM   7257  O OG1 . THR C 3 155 ? 179.699 189.585 237.778 1.00 107.68 ? 199 THR C OG1 1 
ATOM   7258  C CG2 . THR C 3 155 ? 179.345 191.962 237.931 1.00 107.68 ? 199 THR C CG2 1 
ATOM   7259  N N   . LEU C 3 156 ? 175.982 189.263 236.276 1.00 91.29  ? 200 LEU C N   1 
ATOM   7260  C CA  . LEU C 3 156 ? 175.368 188.140 235.580 1.00 91.29  ? 200 LEU C CA  1 
ATOM   7261  C C   . LEU C 3 156 ? 176.182 187.818 234.332 1.00 91.29  ? 200 LEU C C   1 
ATOM   7262  O O   . LEU C 3 156 ? 176.252 188.631 233.404 1.00 91.29  ? 200 LEU C O   1 
ATOM   7263  C CB  . LEU C 3 156 ? 173.919 188.459 235.214 1.00 91.29  ? 200 LEU C CB  1 
ATOM   7264  C CG  . LEU C 3 156 ? 173.097 187.319 234.612 1.00 91.29  ? 200 LEU C CG  1 
ATOM   7265  C CD1 . LEU C 3 156 ? 172.935 186.189 235.616 1.00 91.29  ? 200 LEU C CD1 1 
ATOM   7266  C CD2 . LEU C 3 156 ? 171.741 187.823 234.145 1.00 91.29  ? 200 LEU C CD2 1 
ATOM   7267  N N   . HIS C 3 157 ? 176.791 186.637 234.311 1.00 73.70  ? 201 HIS C N   1 
ATOM   7268  C CA  . HIS C 3 157 ? 177.618 186.216 233.192 1.00 73.70  ? 201 HIS C CA  1 
ATOM   7269  C C   . HIS C 3 157 ? 176.802 185.402 232.193 1.00 73.70  ? 201 HIS C C   1 
ATOM   7270  O O   . HIS C 3 157 ? 175.727 184.883 232.503 1.00 73.70  ? 201 HIS C O   1 
ATOM   7271  C CB  . HIS C 3 157 ? 178.812 185.398 233.683 1.00 73.70  ? 201 HIS C CB  1 
ATOM   7272  C CG  . HIS C 3 157 ? 179.562 186.041 234.807 1.00 73.70  ? 201 HIS C CG  1 
ATOM   7273  N ND1 . HIS C 3 157 ? 179.153 185.953 236.120 1.00 73.70  ? 201 HIS C ND1 1 
ATOM   7274  C CD2 . HIS C 3 157 ? 180.694 186.784 234.814 1.00 73.70  ? 201 HIS C CD2 1 
ATOM   7275  C CE1 . HIS C 3 157 ? 180.002 186.613 236.888 1.00 73.70  ? 201 HIS C CE1 1 
ATOM   7276  N NE2 . HIS C 3 157 ? 180.946 187.126 236.120 1.00 73.70  ? 201 HIS C NE2 1 
ATOM   7277  N N   . HIS C 3 158 ? 177.334 185.295 230.977 1.00 68.41  ? 202 HIS C N   1 
ATOM   7278  C CA  . HIS C 3 158 ? 176.699 184.549 229.902 1.00 68.41  ? 202 HIS C CA  1 
ATOM   7279  C C   . HIS C 3 158 ? 177.706 183.593 229.281 1.00 68.41  ? 202 HIS C C   1 
ATOM   7280  O O   . HIS C 3 158 ? 178.892 183.917 229.163 1.00 68.41  ? 202 HIS C O   1 
ATOM   7281  C CB  . HIS C 3 158 ? 176.136 185.487 228.827 1.00 68.41  ? 202 HIS C CB  1 
ATOM   7282  C CG  . HIS C 3 158 ? 174.978 186.313 229.293 1.00 68.41  ? 202 HIS C CG  1 
ATOM   7283  N ND1 . HIS C 3 158 ? 174.242 185.998 230.415 1.00 68.41  ? 202 HIS C ND1 1 
ATOM   7284  C CD2 . HIS C 3 158 ? 174.429 187.443 228.788 1.00 68.41  ? 202 HIS C CD2 1 
ATOM   7285  C CE1 . HIS C 3 158 ? 173.290 186.898 230.581 1.00 68.41  ? 202 HIS C CE1 1 
ATOM   7286  N NE2 . HIS C 3 158 ? 173.381 187.786 229.608 1.00 68.41  ? 202 HIS C NE2 1 
ATOM   7287  N N   . TRP C 3 159 ? 177.228 182.415 228.886 1.00 56.44  ? 203 TRP C N   1 
ATOM   7288  C CA  . TRP C 3 159 ? 178.065 181.407 228.253 1.00 56.44  ? 203 TRP C CA  1 
ATOM   7289  C C   . TRP C 3 159 ? 177.279 180.724 227.145 1.00 56.44  ? 203 TRP C C   1 
ATOM   7290  O O   . TRP C 3 159 ? 176.100 180.402 227.318 1.00 56.44  ? 203 TRP C O   1 
ATOM   7291  C CB  . TRP C 3 159 ? 178.558 180.367 229.267 1.00 56.44  ? 203 TRP C CB  1 
ATOM   7292  C CG  . TRP C 3 159 ? 179.448 179.323 228.667 1.00 56.44  ? 203 TRP C CG  1 
ATOM   7293  C CD1 . TRP C 3 159 ? 180.740 179.484 228.258 1.00 56.44  ? 203 TRP C CD1 1 
ATOM   7294  C CD2 . TRP C 3 159 ? 179.113 177.954 228.408 1.00 56.44  ? 203 TRP C CD2 1 
ATOM   7295  N NE1 . TRP C 3 159 ? 181.230 178.301 227.760 1.00 56.44  ? 203 TRP C NE1 1 
ATOM   7296  C CE2 . TRP C 3 159 ? 180.251 177.346 227.842 1.00 56.44  ? 203 TRP C CE2 1 
ATOM   7297  C CE3 . TRP C 3 159 ? 177.962 177.184 228.601 1.00 56.44  ? 203 TRP C CE3 1 
ATOM   7298  C CZ2 . TRP C 3 159 ? 180.271 176.004 227.466 1.00 56.44  ? 203 TRP C CZ2 1 
ATOM   7299  C CZ3 . TRP C 3 159 ? 177.984 175.853 228.227 1.00 56.44  ? 203 TRP C CZ3 1 
ATOM   7300  C CH2 . TRP C 3 159 ? 179.130 175.277 227.667 1.00 56.44  ? 203 TRP C CH2 1 
ATOM   7301  N N   . SER C 3 160 ? 177.938 180.508 226.009 1.00 49.22  ? 204 SER C N   1 
ATOM   7302  C CA  . SER C 3 160 ? 177.315 179.894 224.847 1.00 49.22  ? 204 SER C CA  1 
ATOM   7303  C C   . SER C 3 160 ? 178.251 178.855 224.247 1.00 49.22  ? 204 SER C C   1 
ATOM   7304  O O   . SER C 3 160 ? 179.476 179.000 224.292 1.00 49.22  ? 204 SER C O   1 
ATOM   7305  C CB  . SER C 3 160 ? 176.950 180.944 223.789 1.00 49.22  ? 204 SER C CB  1 
ATOM   7306  O OG  . SER C 3 160 ? 176.294 180.349 222.684 1.00 49.22  ? 204 SER C OG  1 
ATOM   7307  N N   . TRP C 3 161 ? 177.659 177.804 223.683 1.00 44.52  ? 205 TRP C N   1 
ATOM   7308  C CA  . TRP C 3 161 ? 178.428 176.740 223.048 1.00 44.52  ? 205 TRP C CA  1 
ATOM   7309  C C   . TRP C 3 161 ? 177.552 176.057 222.011 1.00 44.52  ? 205 TRP C C   1 
ATOM   7310  O O   . TRP C 3 161 ? 176.391 175.742 222.290 1.00 44.52  ? 205 TRP C O   1 
ATOM   7311  C CB  . TRP C 3 161 ? 178.927 175.722 224.079 1.00 44.52  ? 205 TRP C CB  1 
ATOM   7312  C CG  . TRP C 3 161 ? 179.335 174.412 223.476 1.00 44.52  ? 205 TRP C CG  1 
ATOM   7313  C CD1 . TRP C 3 161 ? 180.477 174.152 222.776 1.00 44.52  ? 205 TRP C CD1 1 
ATOM   7314  C CD2 . TRP C 3 161 ? 178.601 173.182 223.517 1.00 44.52  ? 205 TRP C CD2 1 
ATOM   7315  N NE1 . TRP C 3 161 ? 180.500 172.836 222.381 1.00 44.52  ? 205 TRP C NE1 1 
ATOM   7316  C CE2 . TRP C 3 161 ? 179.360 172.219 222.824 1.00 44.52  ? 205 TRP C CE2 1 
ATOM   7317  C CE3 . TRP C 3 161 ? 177.376 172.801 224.075 1.00 44.52  ? 205 TRP C CE3 1 
ATOM   7318  C CZ2 . TRP C 3 161 ? 178.935 170.901 222.671 1.00 44.52  ? 205 TRP C CZ2 1 
ATOM   7319  C CZ3 . TRP C 3 161 ? 176.956 171.492 223.922 1.00 44.52  ? 205 TRP C CZ3 1 
ATOM   7320  C CH2 . TRP C 3 161 ? 177.733 170.558 223.227 1.00 44.52  ? 205 TRP C CH2 1 
ATOM   7321  N N   . ALA C 3 162 ? 178.109 175.825 220.826 1.00 41.85  ? 206 ALA C N   1 
ATOM   7322  C CA  . ALA C 3 162 ? 177.391 175.184 219.734 1.00 41.85  ? 206 ALA C CA  1 
ATOM   7323  C C   . ALA C 3 162 ? 177.657 173.685 219.742 1.00 41.85  ? 206 ALA C C   1 
ATOM   7324  O O   . ALA C 3 162 ? 178.783 173.244 219.987 1.00 41.85  ? 206 ALA C O   1 
ATOM   7325  C CB  . ALA C 3 162 ? 177.801 175.781 218.386 1.00 41.85  ? 206 ALA C CB  1 
ATOM   7326  N N   . SER C 3 163 ? 176.615 172.909 219.467 1.00 45.91  ? 207 SER C N   1 
ATOM   7327  C CA  . SER C 3 163 ? 176.697 171.457 219.457 1.00 45.91  ? 207 SER C CA  1 
ATOM   7328  C C   . SER C 3 163 ? 176.826 170.936 218.031 1.00 45.91  ? 207 SER C C   1 
ATOM   7329  O O   . SER C 3 163 ? 176.537 171.635 217.057 1.00 45.91  ? 207 SER C O   1 
ATOM   7330  C CB  . SER C 3 163 ? 175.468 170.840 220.130 1.00 45.91  ? 207 SER C CB  1 
ATOM   7331  O OG  . SER C 3 163 ? 175.506 169.425 220.061 1.00 45.91  ? 207 SER C OG  1 
ATOM   7332  N N   . ASP C 3 164 ? 177.269 169.683 217.921 1.00 39.24  ? 208 ASP C N   1 
ATOM   7333  C CA  . ASP C 3 164 ? 177.443 169.037 216.628 1.00 39.24  ? 208 ASP C CA  1 
ATOM   7334  C C   . ASP C 3 164 ? 176.330 168.055 216.292 1.00 39.24  ? 208 ASP C C   1 
ATOM   7335  O O   . ASP C 3 164 ? 176.040 167.856 215.108 1.00 39.24  ? 208 ASP C O   1 
ATOM   7336  C CB  . ASP C 3 164 ? 178.788 168.304 216.579 1.00 39.24  ? 208 ASP C CB  1 
ATOM   7337  C CG  . ASP C 3 164 ? 178.999 167.394 217.773 1.00 39.24  ? 208 ASP C CG  1 
ATOM   7338  O OD1 . ASP C 3 164 ? 178.154 167.410 218.692 1.00 39.24  ? 208 ASP C OD1 1 
ATOM   7339  O OD2 . ASP C 3 164 ? 180.011 166.661 217.793 1.00 39.24  ? 208 ASP C OD2 1 
ATOM   7340  N N   . MET C 3 165 ? 175.707 167.444 217.295 1.00 51.94  ? 209 MET C N   1 
ATOM   7341  C CA  . MET C 3 165 ? 174.614 166.504 217.098 1.00 51.94  ? 209 MET C CA  1 
ATOM   7342  C C   . MET C 3 165 ? 173.275 167.196 217.314 1.00 51.94  ? 209 MET C C   1 
ATOM   7343  O O   . MET C 3 165 ? 173.128 167.978 218.260 1.00 51.94  ? 209 MET C O   1 
ATOM   7344  C CB  . MET C 3 165 ? 174.742 165.322 218.060 1.00 51.94  ? 209 MET C CB  1 
ATOM   7345  C CG  . MET C 3 165 ? 173.664 164.263 217.911 1.00 51.94  ? 209 MET C CG  1 
ATOM   7346  S SD  . MET C 3 165 ? 174.090 162.720 218.738 1.00 51.94  ? 209 MET C SD  1 
ATOM   7347  C CE  . MET C 3 165 ? 175.501 162.197 217.767 1.00 51.94  ? 209 MET C CE  1 
ATOM   7348  N N   . PRO C 3 166 ? 172.296 166.940 216.444 1.00 40.59  ? 210 PRO C N   1 
ATOM   7349  C CA  . PRO C 3 166 ? 170.987 167.587 216.595 1.00 40.59  ? 210 PRO C CA  1 
ATOM   7350  C C   . PRO C 3 166 ? 170.369 167.296 217.955 1.00 40.59  ? 210 PRO C C   1 
ATOM   7351  O O   . PRO C 3 166 ? 170.397 166.165 218.445 1.00 40.59  ? 210 PRO C O   1 
ATOM   7352  C CB  . PRO C 3 166 ? 170.160 166.978 215.458 1.00 40.59  ? 210 PRO C CB  1 
ATOM   7353  C CG  . PRO C 3 166 ? 171.169 166.581 214.437 1.00 40.59  ? 210 PRO C CG  1 
ATOM   7354  C CD  . PRO C 3 166 ? 172.381 166.145 215.207 1.00 40.59  ? 210 PRO C CD  1 
ATOM   7355  N N   . LEU C 3 167 ? 169.804 168.340 218.564 1.00 37.08  ? 211 LEU C N   1 
ATOM   7356  C CA  . LEU C 3 167 ? 169.235 168.228 219.900 1.00 37.08  ? 211 LEU C CA  1 
ATOM   7357  C C   . LEU C 3 167 ? 167.951 167.411 219.934 1.00 37.08  ? 211 LEU C C   1 
ATOM   7358  O O   . LEU C 3 167 ? 167.523 167.010 221.022 1.00 37.08  ? 211 LEU C O   1 
ATOM   7359  C CB  . LEU C 3 167 ? 168.971 169.621 220.474 1.00 37.08  ? 211 LEU C CB  1 
ATOM   7360  C CG  . LEU C 3 167 ? 170.146 170.601 220.435 1.00 37.08  ? 211 LEU C CG  1 
ATOM   7361  C CD1 . LEU C 3 167 ? 169.770 171.911 221.107 1.00 37.08  ? 211 LEU C CD1 1 
ATOM   7362  C CD2 . LEU C 3 167 ? 171.376 169.992 221.088 1.00 37.08  ? 211 LEU C CD2 1 
ATOM   7363  N N   . GLU C 3 168 ? 167.330 167.156 218.785 1.00 58.63  ? 212 GLU C N   1 
ATOM   7364  C CA  . GLU C 3 168 ? 166.105 166.369 218.730 1.00 58.63  ? 212 GLU C CA  1 
ATOM   7365  C C   . GLU C 3 168 ? 166.352 164.873 218.873 1.00 58.63  ? 212 GLU C C   1 
ATOM   7366  O O   . GLU C 3 168 ? 165.399 164.093 218.768 1.00 58.63  ? 212 GLU C O   1 
ATOM   7367  C CB  . GLU C 3 168 ? 165.360 166.640 217.420 1.00 58.63  ? 212 GLU C CB  1 
ATOM   7368  C CG  . GLU C 3 168 ? 165.086 168.109 217.147 1.00 58.63  ? 212 GLU C CG  1 
ATOM   7369  C CD  . GLU C 3 168 ? 166.207 168.780 216.378 1.00 58.63  ? 212 GLU C CD  1 
ATOM   7370  O OE1 . GLU C 3 168 ? 167.196 168.093 216.048 1.00 58.63  ? 212 GLU C OE1 1 
ATOM   7371  O OE2 . GLU C 3 168 ? 166.101 169.994 216.103 1.00 58.63  ? 212 GLU C OE2 1 
ATOM   7372  N N   . CYS C 3 169 ? 167.595 164.453 219.106 1.00 64.07  ? 213 CYS C N   1 
ATOM   7373  C CA  . CYS C 3 169 ? 167.931 163.042 219.206 1.00 64.07  ? 213 CYS C CA  1 
ATOM   7374  C C   . CYS C 3 169 ? 168.519 162.650 220.554 1.00 64.07  ? 213 CYS C C   1 
ATOM   7375  O O   . CYS C 3 169 ? 168.797 161.464 220.766 1.00 64.07  ? 213 CYS C O   1 
ATOM   7376  C CB  . CYS C 3 169 ? 168.914 162.653 218.093 1.00 64.07  ? 213 CYS C CB  1 
ATOM   7377  S SG  . CYS C 3 169 ? 168.297 162.949 216.424 1.00 64.07  ? 213 CYS C SG  1 
ATOM   7378  N N   . ALA C 3 170 ? 168.715 163.598 221.467 1.00 52.52  ? 214 ALA C N   1 
ATOM   7379  C CA  . ALA C 3 170 ? 169.304 163.286 222.761 1.00 52.52  ? 214 ALA C CA  1 
ATOM   7380  C C   . ALA C 3 170 ? 168.960 164.387 223.752 1.00 52.52  ? 214 ALA C C   1 
ATOM   7381  O O   . ALA C 3 170 ? 168.770 165.545 223.374 1.00 52.52  ? 214 ALA C O   1 
ATOM   7382  C CB  . ALA C 3 170 ? 170.824 163.118 222.660 1.00 52.52  ? 214 ALA C CB  1 
ATOM   7383  N N   . ILE C 3 171 ? 168.884 164.006 225.025 1.00 52.73  ? 215 ILE C N   1 
ATOM   7384  C CA  . ILE C 3 171 ? 168.658 164.938 226.124 1.00 52.73  ? 215 ILE C CA  1 
ATOM   7385  C C   . ILE C 3 171 ? 170.002 165.270 226.757 1.00 52.73  ? 215 ILE C C   1 
ATOM   7386  O O   . ILE C 3 171 ? 170.881 164.406 226.870 1.00 52.73  ? 215 ILE C O   1 
ATOM   7387  C CB  . ILE C 3 171 ? 167.673 164.352 227.156 1.00 52.73  ? 215 ILE C CB  1 
ATOM   7388  C CG1 . ILE C 3 171 ? 167.346 165.381 228.241 1.00 52.73  ? 215 ILE C CG1 1 
ATOM   7389  C CG2 . ILE C 3 171 ? 168.216 163.065 227.760 1.00 52.73  ? 215 ILE C CG2 1 
ATOM   7390  C CD1 . ILE C 3 171 ? 166.170 164.996 229.112 1.00 52.73  ? 215 ILE C CD1 1 
ATOM   7391  N N   . HIS C 3 172 ? 170.174 166.528 227.153 1.00 34.19  ? 216 HIS C N   1 
ATOM   7392  C CA  . HIS C 3 172 ? 171.445 167.016 227.662 1.00 34.19  ? 216 HIS C CA  1 
ATOM   7393  C C   . HIS C 3 172 ? 171.323 167.442 229.120 1.00 34.19  ? 216 HIS C C   1 
ATOM   7394  O O   . HIS C 3 172 ? 170.226 167.650 229.645 1.00 34.19  ? 216 HIS C O   1 
ATOM   7395  C CB  . HIS C 3 172 ? 171.957 168.189 226.818 1.00 34.19  ? 216 HIS C CB  1 
ATOM   7396  C CG  . HIS C 3 172 ? 172.241 167.828 225.394 1.00 34.19  ? 216 HIS C CG  1 
ATOM   7397  N ND1 . HIS C 3 172 ? 171.249 167.488 224.500 1.00 34.19  ? 216 HIS C ND1 1 
ATOM   7398  C CD2 . HIS C 3 172 ? 173.407 167.752 224.709 1.00 34.19  ? 216 HIS C CD2 1 
ATOM   7399  C CE1 . HIS C 3 172 ? 171.791 167.218 223.325 1.00 34.19  ? 216 HIS C CE1 1 
ATOM   7400  N NE2 . HIS C 3 172 ? 173.099 167.371 223.426 1.00 34.19  ? 216 HIS C NE2 1 
ATOM   7401  N N   . PHE C 3 173 ? 172.479 167.566 229.770 1.00 31.06  ? 217 PHE C N   1 
ATOM   7402  C CA  . PHE C 3 173 ? 172.564 168.008 231.154 1.00 31.06  ? 217 PHE C CA  1 
ATOM   7403  C C   . PHE C 3 173 ? 173.675 169.040 231.276 1.00 31.06  ? 217 PHE C C   1 
ATOM   7404  O O   . PHE C 3 173 ? 174.633 169.036 230.499 1.00 31.06  ? 217 PHE C O   1 
ATOM   7405  C CB  . PHE C 3 173 ? 172.827 166.838 232.113 1.00 31.06  ? 217 PHE C CB  1 
ATOM   7406  C CG  . PHE C 3 173 ? 171.803 165.742 232.031 1.00 31.06  ? 217 PHE C CG  1 
ATOM   7407  C CD1 . PHE C 3 173 ? 170.717 165.726 232.888 1.00 31.06  ? 217 PHE C CD1 1 
ATOM   7408  C CD2 . PHE C 3 173 ? 171.931 164.724 231.101 1.00 31.06  ? 217 PHE C CD2 1 
ATOM   7409  C CE1 . PHE C 3 173 ? 169.776 164.719 232.817 1.00 31.06  ? 217 PHE C CE1 1 
ATOM   7410  C CE2 . PHE C 3 173 ? 170.992 163.715 231.026 1.00 31.06  ? 217 PHE C CE2 1 
ATOM   7411  C CZ  . PHE C 3 173 ? 169.914 163.712 231.885 1.00 31.06  ? 217 PHE C CZ  1 
ATOM   7412  N N   . VAL C 3 174 ? 173.539 169.926 232.260 1.00 33.24  ? 218 VAL C N   1 
ATOM   7413  C CA  . VAL C 3 174 ? 174.476 171.024 232.471 1.00 33.24  ? 218 VAL C CA  1 
ATOM   7414  C C   . VAL C 3 174 ? 174.829 171.090 233.950 1.00 33.24  ? 218 VAL C C   1 
ATOM   7415  O O   . VAL C 3 174 ? 173.938 171.079 234.807 1.00 33.24  ? 218 VAL C O   1 
ATOM   7416  C CB  . VAL C 3 174 ? 173.894 172.369 231.994 1.00 33.24  ? 218 VAL C CB  1 
ATOM   7417  C CG1 . VAL C 3 174 ? 174.774 173.523 232.444 1.00 33.24  ? 218 VAL C CG1 1 
ATOM   7418  C CG2 . VAL C 3 174 ? 173.738 172.375 230.480 1.00 33.24  ? 218 VAL C CG2 1 
ATOM   7419  N N   . GLU C 3 175 ? 176.127 171.157 234.246 1.00 44.07  ? 219 GLU C N   1 
ATOM   7420  C CA  . GLU C 3 175 ? 176.614 171.330 235.606 1.00 44.07  ? 219 GLU C CA  1 
ATOM   7421  C C   . GLU C 3 175 ? 177.791 172.294 235.593 1.00 44.07  ? 219 GLU C C   1 
ATOM   7422  O O   . GLU C 3 175 ? 178.557 172.347 234.627 1.00 44.07  ? 219 GLU C O   1 
ATOM   7423  C CB  . GLU C 3 175 ? 177.033 169.994 236.236 1.00 44.07  ? 219 GLU C CB  1 
ATOM   7424  C CG  . GLU C 3 175 ? 175.876 169.188 236.804 1.00 44.07  ? 219 GLU C CG  1 
ATOM   7425  C CD  . GLU C 3 175 ? 176.332 167.903 237.466 1.00 44.07  ? 219 GLU C CD  1 
ATOM   7426  O OE1 . GLU C 3 175 ? 177.306 167.293 236.978 1.00 44.07  ? 219 GLU C OE1 1 
ATOM   7427  O OE2 . GLU C 3 175 ? 175.716 167.503 238.477 1.00 44.07  ? 219 GLU C OE2 1 
ATOM   7428  N N   . ILE C 3 176 ? 177.929 173.056 236.675 1.00 61.58  ? 220 ILE C N   1 
ATOM   7429  C CA  . ILE C 3 176 ? 178.965 174.080 236.768 1.00 61.58  ? 220 ILE C CA  1 
ATOM   7430  C C   . ILE C 3 176 ? 179.295 174.310 238.237 1.00 61.58  ? 220 ILE C C   1 
ATOM   7431  O O   . ILE C 3 176 ? 178.417 174.252 239.103 1.00 61.58  ? 220 ILE C O   1 
ATOM   7432  C CB  . ILE C 3 176 ? 178.520 175.388 236.074 1.00 61.58  ? 220 ILE C CB  1 
ATOM   7433  C CG1 . ILE C 3 176 ? 179.624 176.446 236.142 1.00 61.58  ? 220 ILE C CG1 1 
ATOM   7434  C CG2 . ILE C 3 176 ? 177.224 175.909 236.681 1.00 61.58  ? 220 ILE C CG2 1 
ATOM   7435  C CD1 . ILE C 3 176 ? 179.236 177.774 235.531 1.00 61.58  ? 220 ILE C CD1 1 
ATOM   7436  N N   . ARG C 3 177 ? 180.575 174.558 238.514 1.00 69.21  ? 221 ARG C N   1 
ATOM   7437  C CA  . ARG C 3 177 ? 181.046 174.880 239.853 1.00 69.21  ? 221 ARG C CA  1 
ATOM   7438  C C   . ARG C 3 177 ? 181.995 176.068 239.758 1.00 69.21  ? 221 ARG C C   1 
ATOM   7439  O O   . ARG C 3 177 ? 182.264 176.587 238.670 1.00 69.21  ? 221 ARG C O   1 
ATOM   7440  C CB  . ARG C 3 177 ? 181.726 173.673 240.509 1.00 69.21  ? 221 ARG C CB  1 
ATOM   7441  C CG  . ARG C 3 177 ? 182.941 173.163 239.754 1.00 69.21  ? 221 ARG C CG  1 
ATOM   7442  C CD  . ARG C 3 177 ? 183.610 172.021 240.498 1.00 69.21  ? 221 ARG C CD  1 
ATOM   7443  N NE  . ARG C 3 177 ? 184.729 171.461 239.747 1.00 69.21  ? 221 ARG C NE  1 
ATOM   7444  C CZ  . ARG C 3 177 ? 185.473 170.443 240.166 1.00 69.21  ? 221 ARG C CZ  1 
ATOM   7445  N NH1 . ARG C 3 177 ? 185.218 169.870 241.334 1.00 69.21  ? 221 ARG C NH1 1 
ATOM   7446  N NH2 . ARG C 3 177 ? 186.472 169.998 239.417 1.00 69.21  ? 221 ARG C NH2 1 
ATOM   7447  N N   . CYS C 3 178 ? 182.508 176.502 240.907 1.00 99.68  ? 222 CYS C N   1 
ATOM   7448  C CA  . CYS C 3 178 ? 183.394 177.656 240.963 1.00 99.68  ? 222 CYS C CA  1 
ATOM   7449  C C   . CYS C 3 178 ? 184.544 177.377 241.918 1.00 99.68  ? 222 CYS C C   1 
ATOM   7450  O O   . CYS C 3 178 ? 184.480 176.478 242.760 1.00 99.68  ? 222 CYS C O   1 
ATOM   7451  C CB  . CYS C 3 178 ? 182.645 178.923 241.399 1.00 99.68  ? 222 CYS C CB  1 
ATOM   7452  S SG  . CYS C 3 178 ? 182.425 179.080 243.186 1.00 99.68  ? 222 CYS C SG  1 
ATOM   7453  N N   . TYR C 3 179 ? 185.606 178.168 241.773 1.00 145.99 ? 223 TYR C N   1 
ATOM   7454  C CA  . TYR C 3 179 ? 186.769 178.077 242.651 1.00 145.99 ? 223 TYR C CA  1 
ATOM   7455  C C   . TYR C 3 179 ? 187.450 179.438 242.656 1.00 145.99 ? 223 TYR C C   1 
ATOM   7456  O O   . TYR C 3 179 ? 188.093 179.813 241.671 1.00 145.99 ? 223 TYR C O   1 
ATOM   7457  C CB  . TYR C 3 179 ? 187.727 176.982 242.191 1.00 145.99 ? 223 TYR C CB  1 
ATOM   7458  C CG  . TYR C 3 179 ? 189.006 176.908 242.995 1.00 145.99 ? 223 TYR C CG  1 
ATOM   7459  C CD1 . TYR C 3 179 ? 190.213 177.338 242.459 1.00 145.99 ? 223 TYR C CD1 1 
ATOM   7460  C CD2 . TYR C 3 179 ? 189.006 176.410 244.292 1.00 145.99 ? 223 TYR C CD2 1 
ATOM   7461  C CE1 . TYR C 3 179 ? 191.384 177.271 243.190 1.00 145.99 ? 223 TYR C CE1 1 
ATOM   7462  C CE2 . TYR C 3 179 ? 190.172 176.341 245.031 1.00 145.99 ? 223 TYR C CE2 1 
ATOM   7463  C CZ  . TYR C 3 179 ? 191.358 176.773 244.476 1.00 145.99 ? 223 TYR C CZ  1 
ATOM   7464  O OH  . TYR C 3 179 ? 192.521 176.706 245.207 1.00 145.99 ? 223 TYR C OH  1 
ATOM   7465  N N   . ILE C 3 180 ? 187.310 180.170 243.756 1.00 186.90 ? 224 ILE C N   1 
ATOM   7466  C CA  . ILE C 3 180 ? 187.841 181.524 243.843 1.00 186.90 ? 224 ILE C CA  1 
ATOM   7467  C C   . ILE C 3 180 ? 189.311 181.478 244.237 1.00 186.90 ? 224 ILE C C   1 
ATOM   7468  O O   . ILE C 3 180 ? 189.795 180.502 244.822 1.00 186.90 ? 224 ILE C O   1 
ATOM   7469  C CB  . ILE C 3 180 ? 187.021 182.368 244.839 1.00 186.90 ? 224 ILE C CB  1 
ATOM   7470  C CG1 . ILE C 3 180 ? 186.864 181.624 246.165 1.00 186.90 ? 224 ILE C CG1 1 
ATOM   7471  C CG2 . ILE C 3 180 ? 185.659 182.705 244.256 1.00 186.90 ? 224 ILE C CG2 1 
ATOM   7472  C CD1 . ILE C 3 180 ? 186.647 182.538 247.350 1.00 186.90 ? 224 ILE C CD1 1 
ATOM   7473  N N   . ASP C 3 181 ? 190.030 182.549 243.910 1.00 201.27 ? 225 ASP C N   1 
ATOM   7474  C CA  . ASP C 3 181 ? 191.445 182.694 244.238 1.00 201.27 ? 225 ASP C CA  1 
ATOM   7475  C C   . ASP C 3 181 ? 191.626 184.007 244.987 1.00 201.27 ? 225 ASP C C   1 
ATOM   7476  O O   . ASP C 3 181 ? 191.445 185.085 244.411 1.00 201.27 ? 225 ASP C O   1 
ATOM   7477  C CB  . ASP C 3 181 ? 192.308 182.658 242.977 1.00 201.27 ? 225 ASP C CB  1 
ATOM   7478  C CG  . ASP C 3 181 ? 192.230 181.328 242.257 1.00 201.27 ? 225 ASP C CG  1 
ATOM   7479  O OD1 . ASP C 3 181 ? 192.122 180.287 242.938 1.00 201.27 ? 225 ASP C OD1 1 
ATOM   7480  O OD2 . ASP C 3 181 ? 192.278 181.322 241.009 1.00 201.27 ? 225 ASP C OD2 1 
ATOM   7481  N N   . ASN C 3 182 ? 191.980 183.918 246.267 1.00 231.59 ? 226 ASN C N   1 
ATOM   7482  C CA  . ASN C 3 182 ? 192.191 185.088 247.113 1.00 231.59 ? 226 ASN C CA  1 
ATOM   7483  C C   . ASN C 3 182 ? 193.660 185.136 247.513 1.00 231.59 ? 226 ASN C C   1 
ATOM   7484  O O   . ASN C 3 182 ? 194.135 184.267 248.254 1.00 231.59 ? 226 ASN C O   1 
ATOM   7485  C CB  . ASN C 3 182 ? 191.287 185.049 248.344 1.00 231.59 ? 226 ASN C CB  1 
ATOM   7486  C CG  . ASN C 3 182 ? 191.338 186.335 249.144 1.00 231.59 ? 226 ASN C CG  1 
ATOM   7487  O OD1 . ASN C 3 182 ? 192.169 186.492 250.038 1.00 231.59 ? 226 ASN C OD1 1 
ATOM   7488  N ND2 . ASN C 3 182 ? 190.450 187.268 248.821 1.00 231.59 ? 226 ASN C ND2 1 
ATOM   7489  N N   . LEU C 3 183 ? 194.376 186.151 247.025 1.00 235.53 ? 227 LEU C N   1 
ATOM   7490  C CA  . LEU C 3 183 ? 195.791 186.291 247.346 1.00 235.53 ? 227 LEU C CA  1 
ATOM   7491  C C   . LEU C 3 183 ? 196.020 186.700 248.795 1.00 235.53 ? 227 LEU C C   1 
ATOM   7492  O O   . LEU C 3 183 ? 197.104 186.449 249.332 1.00 235.53 ? 227 LEU C O   1 
ATOM   7493  C CB  . LEU C 3 183 ? 196.444 187.309 246.410 1.00 235.53 ? 227 LEU C CB  1 
ATOM   7494  C CG  . LEU C 3 183 ? 196.280 187.048 244.912 1.00 235.53 ? 227 LEU C CG  1 
ATOM   7495  C CD1 . LEU C 3 183 ? 197.013 188.105 244.100 1.00 235.53 ? 227 LEU C CD1 1 
ATOM   7496  C CD2 . LEU C 3 183 ? 196.768 185.654 244.552 1.00 235.53 ? 227 LEU C CD2 1 
ATOM   7497  N N   . HIS C 3 184 ? 195.030 187.321 249.436 1.00 237.23 ? 228 HIS C N   1 
ATOM   7498  C CA  . HIS C 3 184 ? 195.161 187.736 250.826 1.00 237.23 ? 228 HIS C CA  1 
ATOM   7499  C C   . HIS C 3 184 ? 194.835 186.623 251.813 1.00 237.23 ? 228 HIS C C   1 
ATOM   7500  O O   . HIS C 3 184 ? 195.096 186.785 253.010 1.00 237.23 ? 228 HIS C O   1 
ATOM   7501  C CB  . HIS C 3 184 ? 194.262 188.944 251.100 1.00 237.23 ? 228 HIS C CB  1 
ATOM   7502  C CG  . HIS C 3 184 ? 194.539 190.117 250.213 1.00 237.23 ? 228 HIS C CG  1 
ATOM   7503  N ND1 . HIS C 3 184 ? 195.425 191.115 250.554 1.00 237.23 ? 228 HIS C ND1 1 
ATOM   7504  C CD2 . HIS C 3 184 ? 194.048 190.450 248.996 1.00 237.23 ? 228 HIS C CD2 1 
ATOM   7505  C CE1 . HIS C 3 184 ? 195.467 192.014 249.587 1.00 237.23 ? 228 HIS C CE1 1 
ATOM   7506  N NE2 . HIS C 3 184 ? 194.641 191.634 248.629 1.00 237.23 ? 228 HIS C NE2 1 
ATOM   7507  N N   . PHE C 3 185 ? 194.276 185.509 251.348 1.00 231.26 ? 229 PHE C N   1 
ATOM   7508  C CA  . PHE C 3 185 ? 193.941 184.387 252.214 1.00 231.26 ? 229 PHE C CA  1 
ATOM   7509  C C   . PHE C 3 185 ? 195.083 183.378 252.189 1.00 231.26 ? 229 PHE C C   1 
ATOM   7510  O O   . PHE C 3 185 ? 195.371 182.784 251.145 1.00 231.26 ? 229 PHE C O   1 
ATOM   7511  C CB  . PHE C 3 185 ? 192.631 183.736 251.770 1.00 231.26 ? 229 PHE C CB  1 
ATOM   7512  C CG  . PHE C 3 185 ? 192.040 182.802 252.788 1.00 231.26 ? 229 PHE C CG  1 
ATOM   7513  C CD1 . PHE C 3 185 ? 191.921 181.449 252.519 1.00 231.26 ? 229 PHE C CD1 1 
ATOM   7514  C CD2 . PHE C 3 185 ? 191.606 183.277 254.014 1.00 231.26 ? 229 PHE C CD2 1 
ATOM   7515  C CE1 . PHE C 3 185 ? 191.377 180.588 253.453 1.00 231.26 ? 229 PHE C CE1 1 
ATOM   7516  C CE2 . PHE C 3 185 ? 191.062 182.421 254.952 1.00 231.26 ? 229 PHE C CE2 1 
ATOM   7517  C CZ  . PHE C 3 185 ? 190.948 181.075 254.671 1.00 231.26 ? 229 PHE C CZ  1 
ATOM   7518  N N   . SER C 3 186 ? 195.729 183.189 253.337 1.00 231.95 ? 230 SER C N   1 
ATOM   7519  C CA  . SER C 3 186 ? 196.858 182.277 253.455 1.00 231.95 ? 230 SER C CA  1 
ATOM   7520  C C   . SER C 3 186 ? 196.440 180.854 253.800 1.00 231.95 ? 230 SER C C   1 
ATOM   7521  O O   . SER C 3 186 ? 197.307 179.982 253.923 1.00 231.95 ? 230 SER C O   1 
ATOM   7522  C CB  . SER C 3 186 ? 197.843 182.792 254.510 1.00 231.95 ? 230 SER C CB  1 
ATOM   7523  O OG  . SER C 3 186 ? 198.987 181.960 254.590 1.00 231.95 ? 230 SER C OG  1 
ATOM   7524  N N   . GLY C 3 187 ? 195.145 180.598 253.959 1.00 226.56 ? 231 GLY C N   1 
ATOM   7525  C CA  . GLY C 3 187 ? 194.661 179.273 254.277 1.00 226.56 ? 231 GLY C CA  1 
ATOM   7526  C C   . GLY C 3 187 ? 194.486 178.413 253.041 1.00 226.56 ? 231 GLY C C   1 
ATOM   7527  O O   . GLY C 3 187 ? 194.952 178.727 251.944 1.00 226.56 ? 231 GLY C O   1 
ATOM   7528  N N   . LEU C 3 188 ? 193.790 177.296 253.235 1.00 215.39 ? 232 LEU C N   1 
ATOM   7529  C CA  . LEU C 3 188 ? 193.537 176.345 252.161 1.00 215.39 ? 232 LEU C CA  1 
ATOM   7530  C C   . LEU C 3 188 ? 192.289 176.758 251.393 1.00 215.39 ? 232 LEU C C   1 
ATOM   7531  O O   . LEU C 3 188 ? 191.257 177.072 251.995 1.00 215.39 ? 232 LEU C O   1 
ATOM   7532  C CB  . LEU C 3 188 ? 193.373 174.927 252.713 1.00 215.39 ? 232 LEU C CB  1 
ATOM   7533  C CG  . LEU C 3 188 ? 194.625 174.098 253.027 1.00 215.39 ? 232 LEU C CG  1 
ATOM   7534  C CD1 . LEU C 3 188 ? 195.401 173.791 251.752 1.00 215.39 ? 232 LEU C CD1 1 
ATOM   7535  C CD2 . LEU C 3 188 ? 195.524 174.763 254.064 1.00 215.39 ? 232 LEU C CD2 1 
ATOM   7536  N N   . GLU C 3 189 ? 192.389 176.759 250.067 1.00 194.03 ? 233 GLU C N   1 
ATOM   7537  C CA  . GLU C 3 189 ? 191.284 177.112 249.185 1.00 194.03 ? 233 GLU C CA  1 
ATOM   7538  C C   . GLU C 3 189 ? 190.739 175.840 248.551 1.00 194.03 ? 233 GLU C C   1 
ATOM   7539  O O   . GLU C 3 189 ? 191.471 175.125 247.858 1.00 194.03 ? 233 GLU C O   1 
ATOM   7540  C CB  . GLU C 3 189 ? 191.736 178.100 248.110 1.00 194.03 ? 233 GLU C CB  1 
ATOM   7541  C CG  . GLU C 3 189 ? 192.538 179.274 248.644 1.00 194.03 ? 233 GLU C CG  1 
ATOM   7542  C CD  . GLU C 3 189 ? 192.917 180.262 247.558 1.00 194.03 ? 233 GLU C CD  1 
ATOM   7543  O OE1 . GLU C 3 189 ? 192.252 180.269 246.501 1.00 194.03 ? 233 GLU C OE1 1 
ATOM   7544  O OE2 . GLU C 3 189 ? 193.879 181.031 247.762 1.00 194.03 ? 233 GLU C OE2 1 
ATOM   7545  N N   . GLU C 3 190 ? 189.461 175.561 248.788 1.00 179.36 ? 234 GLU C N   1 
ATOM   7546  C CA  . GLU C 3 190 ? 188.806 174.369 248.273 1.00 179.36 ? 234 GLU C CA  1 
ATOM   7547  C C   . GLU C 3 190 ? 187.815 174.741 247.178 1.00 179.36 ? 234 GLU C C   1 
ATOM   7548  O O   . GLU C 3 190 ? 187.351 175.881 247.085 1.00 179.36 ? 234 GLU C O   1 
ATOM   7549  C CB  . GLU C 3 190 ? 188.084 173.602 249.389 1.00 179.36 ? 234 GLU C CB  1 
ATOM   7550  C CG  . GLU C 3 190 ? 188.983 172.755 250.288 1.00 179.36 ? 234 GLU C CG  1 
ATOM   7551  C CD  . GLU C 3 190 ? 190.170 173.519 250.841 1.00 179.36 ? 234 GLU C CD  1 
ATOM   7552  O OE1 . GLU C 3 190 ? 191.307 173.012 250.737 1.00 179.36 ? 234 GLU C OE1 1 
ATOM   7553  O OE2 . GLU C 3 190 ? 189.965 174.626 251.380 1.00 179.36 ? 234 GLU C OE2 1 
ATOM   7554  N N   . TRP C 3 191 ? 187.493 173.755 246.347 1.00 100.98 ? 235 TRP C N   1 
ATOM   7555  C CA  . TRP C 3 191 ? 186.536 173.952 245.270 1.00 100.98 ? 235 TRP C CA  1 
ATOM   7556  C C   . TRP C 3 191 ? 185.112 173.927 245.810 1.00 100.98 ? 235 TRP C C   1 
ATOM   7557  O O   . TRP C 3 191 ? 184.809 173.254 246.799 1.00 100.98 ? 235 TRP C O   1 
ATOM   7558  C CB  . TRP C 3 191 ? 186.700 172.874 244.198 1.00 100.98 ? 235 TRP C CB  1 
ATOM   7559  C CG  . TRP C 3 191 ? 187.848 173.114 243.269 1.00 100.98 ? 235 TRP C CG  1 
ATOM   7560  C CD1 . TRP C 3 191 ? 189.176 173.022 243.566 1.00 100.98 ? 235 TRP C CD1 1 
ATOM   7561  C CD2 . TRP C 3 191 ? 187.769 173.479 241.886 1.00 100.98 ? 235 TRP C CD2 1 
ATOM   7562  N NE1 . TRP C 3 191 ? 189.930 173.311 242.455 1.00 100.98 ? 235 TRP C NE1 1 
ATOM   7563  C CE2 . TRP C 3 191 ? 189.090 173.595 241.410 1.00 100.98 ? 235 TRP C CE2 1 
ATOM   7564  C CE3 . TRP C 3 191 ? 186.711 173.722 241.006 1.00 100.98 ? 235 TRP C CE3 1 
ATOM   7565  C CZ2 . TRP C 3 191 ? 189.381 173.942 240.092 1.00 100.98 ? 235 TRP C CZ2 1 
ATOM   7566  C CZ3 . TRP C 3 191 ? 187.001 174.066 239.698 1.00 100.98 ? 235 TRP C CZ3 1 
ATOM   7567  C CH2 . TRP C 3 191 ? 188.325 174.172 239.254 1.00 100.98 ? 235 TRP C CH2 1 
ATOM   7568  N N   . SER C 3 192 ? 184.235 174.675 245.148 1.00 91.41  ? 236 SER C N   1 
ATOM   7569  C CA  . SER C 3 192 ? 182.833 174.693 245.529 1.00 91.41  ? 236 SER C CA  1 
ATOM   7570  C C   . SER C 3 192 ? 182.120 173.455 244.995 1.00 91.41  ? 236 SER C C   1 
ATOM   7571  O O   . SER C 3 192 ? 182.565 172.810 244.041 1.00 91.41  ? 236 SER C O   1 
ATOM   7572  C CB  . SER C 3 192 ? 182.148 175.958 245.012 1.00 91.41  ? 236 SER C CB  1 
ATOM   7573  O OG  . SER C 3 192 ? 182.151 175.997 243.596 1.00 91.41  ? 236 SER C OG  1 
ATOM   7574  N N   . ASP C 3 193 ? 180.998 173.127 245.628 1.00 77.07  ? 237 ASP C N   1 
ATOM   7575  C CA  . ASP C 3 193 ? 180.221 171.972 245.213 1.00 77.07  ? 237 ASP C CA  1 
ATOM   7576  C C   . ASP C 3 193 ? 179.568 172.224 243.857 1.00 77.07  ? 237 ASP C C   1 
ATOM   7577  O O   . ASP C 3 193 ? 179.435 173.363 243.398 1.00 77.07  ? 237 ASP C O   1 
ATOM   7578  C CB  . ASP C 3 193 ? 179.156 171.640 246.258 1.00 77.07  ? 237 ASP C CB  1 
ATOM   7579  C CG  . ASP C 3 193 ? 179.746 171.381 247.629 1.00 77.07  ? 237 ASP C CG  1 
ATOM   7580  O OD1 . ASP C 3 193 ? 180.886 170.875 247.701 1.00 77.07  ? 237 ASP C OD1 1 
ATOM   7581  O OD2 . ASP C 3 193 ? 179.072 171.684 248.635 1.00 77.07  ? 237 ASP C OD2 1 
ATOM   7582  N N   . TRP C 3 194 ? 179.161 171.135 243.211 1.00 59.36  ? 238 TRP C N   1 
ATOM   7583  C CA  . TRP C 3 194 ? 178.505 171.240 241.916 1.00 59.36  ? 238 TRP C CA  1 
ATOM   7584  C C   . TRP C 3 194 ? 177.070 171.723 242.084 1.00 59.36  ? 238 TRP C C   1 
ATOM   7585  O O   . TRP C 3 194 ? 176.376 171.347 243.033 1.00 59.36  ? 238 TRP C O   1 
ATOM   7586  C CB  . TRP C 3 194 ? 178.526 169.891 241.198 1.00 59.36  ? 238 TRP C CB  1 
ATOM   7587  C CG  . TRP C 3 194 ? 179.898 169.445 240.800 1.00 59.36  ? 238 TRP C CG  1 
ATOM   7588  C CD1 . TRP C 3 194 ? 180.774 168.720 241.552 1.00 59.36  ? 238 TRP C CD1 1 
ATOM   7589  C CD2 . TRP C 3 194 ? 180.554 169.695 239.550 1.00 59.36  ? 238 TRP C CD2 1 
ATOM   7590  N NE1 . TRP C 3 194 ? 181.935 168.502 240.850 1.00 59.36  ? 238 TRP C NE1 1 
ATOM   7591  C CE2 . TRP C 3 194 ? 181.825 169.091 239.618 1.00 59.36  ? 238 TRP C CE2 1 
ATOM   7592  C CE3 . TRP C 3 194 ? 180.190 170.371 238.382 1.00 59.36  ? 238 TRP C CE3 1 
ATOM   7593  C CZ2 . TRP C 3 194 ? 182.732 169.141 238.562 1.00 59.36  ? 238 TRP C CZ2 1 
ATOM   7594  C CZ3 . TRP C 3 194 ? 181.093 170.421 237.335 1.00 59.36  ? 238 TRP C CZ3 1 
ATOM   7595  C CH2 . TRP C 3 194 ? 182.349 169.810 237.432 1.00 59.36  ? 238 TRP C CH2 1 
ATOM   7596  N N   . SER C 3 195 ? 176.629 172.565 241.154 1.00 53.37  ? 239 SER C N   1 
ATOM   7597  C CA  . SER C 3 195 ? 175.272 173.075 241.186 1.00 53.37  ? 239 SER C CA  1 
ATOM   7598  C C   . SER C 3 195 ? 174.279 171.955 240.884 1.00 53.37  ? 239 SER C C   1 
ATOM   7599  O O   . SER C 3 195 ? 174.643 170.935 240.294 1.00 53.37  ? 239 SER C O   1 
ATOM   7600  C CB  . SER C 3 195 ? 175.111 174.208 240.175 1.00 53.37  ? 239 SER C CB  1 
ATOM   7601  O OG  . SER C 3 195 ? 174.767 173.703 238.897 1.00 53.37  ? 239 SER C OG  1 
ATOM   7602  N N   . PRO C 3 196 ? 173.021 172.113 241.298 1.00 37.23  ? 240 PRO C N   1 
ATOM   7603  C CA  . PRO C 3 196 ? 172.003 171.121 240.934 1.00 37.23  ? 240 PRO C CA  1 
ATOM   7604  C C   . PRO C 3 196 ? 171.883 170.991 239.423 1.00 37.23  ? 240 PRO C C   1 
ATOM   7605  O O   . PRO C 3 196 ? 172.007 171.971 238.685 1.00 37.23  ? 240 PRO C O   1 
ATOM   7606  C CB  . PRO C 3 196 ? 170.721 171.681 241.559 1.00 37.23  ? 240 PRO C CB  1 
ATOM   7607  C CG  . PRO C 3 196 ? 171.197 172.523 242.690 1.00 37.23  ? 240 PRO C CG  1 
ATOM   7608  C CD  . PRO C 3 196 ? 172.498 173.120 242.237 1.00 37.23  ? 240 PRO C CD  1 
ATOM   7609  N N   . VAL C 3 197 ? 171.644 169.763 238.968 1.00 35.84  ? 241 VAL C N   1 
ATOM   7610  C CA  . VAL C 3 197 ? 171.613 169.482 237.538 1.00 35.84  ? 241 VAL C CA  1 
ATOM   7611  C C   . VAL C 3 197 ? 170.414 170.181 236.906 1.00 35.84  ? 241 VAL C C   1 
ATOM   7612  O O   . VAL C 3 197 ? 169.284 170.086 237.397 1.00 35.84  ? 241 VAL C O   1 
ATOM   7613  C CB  . VAL C 3 197 ? 171.610 167.968 237.274 1.00 35.84  ? 241 VAL C CB  1 
ATOM   7614  C CG1 . VAL C 3 197 ? 170.308 167.315 237.733 1.00 35.84  ? 241 VAL C CG1 1 
ATOM   7615  C CG2 . VAL C 3 197 ? 171.855 167.690 235.798 1.00 35.84  ? 241 VAL C CG2 1 
ATOM   7616  N N   . LYS C 3 198 ? 170.670 170.934 235.839 1.00 34.60  ? 242 LYS C N   1 
ATOM   7617  C CA  . LYS C 3 198 ? 169.631 171.617 235.075 1.00 34.60  ? 242 LYS C CA  1 
ATOM   7618  C C   . LYS C 3 198 ? 169.670 171.082 233.650 1.00 34.60  ? 242 LYS C C   1 
ATOM   7619  O O   . LYS C 3 198 ? 170.587 171.403 232.887 1.00 34.60  ? 242 LYS C O   1 
ATOM   7620  C CB  . LYS C 3 198 ? 169.829 173.131 235.105 1.00 34.60  ? 242 LYS C CB  1 
ATOM   7621  C CG  . LYS C 3 198 ? 168.775 173.878 235.909 1.00 34.60  ? 242 LYS C CG  1 
ATOM   7622  C CD  . LYS C 3 198 ? 168.698 173.360 237.336 1.00 34.60  ? 242 LYS C CD  1 
ATOM   7623  C CE  . LYS C 3 198 ? 167.621 174.080 238.130 1.00 34.60  ? 242 LYS C CE  1 
ATOM   7624  N NZ  . LYS C 3 198 ? 167.521 173.564 239.524 1.00 34.60  ? 242 LYS C NZ  1 
ATOM   7625  N N   . ASN C 3 199 ? 168.682 170.271 233.296 1.00 36.66  ? 243 ASN C N   1 
ATOM   7626  C CA  . ASN C 3 199 ? 168.620 169.638 231.989 1.00 36.66  ? 243 ASN C CA  1 
ATOM   7627  C C   . ASN C 3 199 ? 167.642 170.370 231.079 1.00 36.66  ? 243 ASN C C   1 
ATOM   7628  O O   . ASN C 3 199 ? 166.737 171.075 231.532 1.00 36.66  ? 243 ASN C O   1 
ATOM   7629  C CB  . ASN C 3 199 ? 168.203 168.172 232.120 1.00 36.66  ? 243 ASN C CB  1 
ATOM   7630  C CG  . ASN C 3 199 ? 166.804 168.018 232.672 1.00 36.66  ? 243 ASN C CG  1 
ATOM   7631  O OD1 . ASN C 3 199 ? 166.398 168.756 233.570 1.00 36.66  ? 243 ASN C OD1 1 
ATOM   7632  N ND2 . ASN C 3 199 ? 166.054 167.059 232.135 1.00 36.66  ? 243 ASN C ND2 1 
ATOM   7633  N N   . ILE C 3 200 ? 167.837 170.186 229.776 1.00 54.38  ? 244 ILE C N   1 
ATOM   7634  C CA  . ILE C 3 200 ? 166.945 170.718 228.753 1.00 54.38  ? 244 ILE C CA  1 
ATOM   7635  C C   . ILE C 3 200 ? 166.285 169.541 228.050 1.00 54.38  ? 244 ILE C C   1 
ATOM   7636  O O   . ILE C 3 200 ? 166.956 168.564 227.698 1.00 54.38  ? 244 ILE C O   1 
ATOM   7637  C CB  . ILE C 3 200 ? 167.694 171.622 227.753 1.00 54.38  ? 244 ILE C CB  1 
ATOM   7638  C CG1 . ILE C 3 200 ? 166.759 172.074 226.628 1.00 54.38  ? 244 ILE C CG1 1 
ATOM   7639  C CG2 . ILE C 3 200 ? 168.932 170.924 227.202 1.00 54.38  ? 244 ILE C CG2 1 
ATOM   7640  C CD1 . ILE C 3 200 ? 165.616 172.948 227.096 1.00 54.38  ? 244 ILE C CD1 1 
ATOM   7641  N N   . SER C 3 201 ? 164.971 169.627 227.862 1.00 75.49  ? 245 SER C N   1 
ATOM   7642  C CA  . SER C 3 201 ? 164.197 168.548 227.271 1.00 75.49  ? 245 SER C CA  1 
ATOM   7643  C C   . SER C 3 201 ? 163.429 169.068 226.067 1.00 75.49  ? 245 SER C C   1 
ATOM   7644  O O   . SER C 3 201 ? 162.874 170.170 226.101 1.00 75.49  ? 245 SER C O   1 
ATOM   7645  C CB  . SER C 3 201 ? 163.225 167.940 228.290 1.00 75.49  ? 245 SER C CB  1 
ATOM   7646  O OG  . SER C 3 201 ? 163.861 167.734 229.539 1.00 75.49  ? 245 SER C OG  1 
ATOM   7647  N N   . TRP C 3 202 ? 163.400 168.268 225.006 1.00 95.39  ? 246 TRP C N   1 
ATOM   7648  C CA  . TRP C 3 202 ? 162.669 168.595 223.792 1.00 95.39  ? 246 TRP C CA  1 
ATOM   7649  C C   . TRP C 3 202 ? 161.448 167.695 223.672 1.00 95.39  ? 246 TRP C C   1 
ATOM   7650  O O   . TRP C 3 202 ? 161.522 166.492 223.944 1.00 95.39  ? 246 TRP C O   1 
ATOM   7651  C CB  . TRP C 3 202 ? 163.556 168.441 222.554 1.00 95.39  ? 246 TRP C CB  1 
ATOM   7652  C CG  . TRP C 3 202 ? 162.819 168.650 221.269 1.00 95.39  ? 246 TRP C CG  1 
ATOM   7653  C CD1 . TRP C 3 202 ? 162.287 169.819 220.811 1.00 95.39  ? 246 TRP C CD1 1 
ATOM   7654  C CD2 . TRP C 3 202 ? 162.526 167.660 220.277 1.00 95.39  ? 246 TRP C CD2 1 
ATOM   7655  N NE1 . TRP C 3 202 ? 161.682 169.619 219.594 1.00 95.39  ? 246 TRP C NE1 1 
ATOM   7656  C CE2 . TRP C 3 202 ? 161.815 168.302 219.243 1.00 95.39  ? 246 TRP C CE2 1 
ATOM   7657  C CE3 . TRP C 3 202 ? 162.796 166.293 220.162 1.00 95.39  ? 246 TRP C CE3 1 
ATOM   7658  C CZ2 . TRP C 3 202 ? 161.372 167.625 218.110 1.00 95.39  ? 246 TRP C CZ2 1 
ATOM   7659  C CZ3 . TRP C 3 202 ? 162.355 165.623 219.036 1.00 95.39  ? 246 TRP C CZ3 1 
ATOM   7660  C CH2 . TRP C 3 202 ? 161.651 166.289 218.025 1.00 95.39  ? 246 TRP C CH2 1 
ATOM   7661  N N   . ILE C 3 203 ? 160.327 168.281 223.264 1.00 122.05 ? 247 ILE C N   1 
ATOM   7662  C CA  . ILE C 3 203 ? 159.075 167.544 223.119 1.00 122.05 ? 247 ILE C CA  1 
ATOM   7663  C C   . ILE C 3 203 ? 159.098 166.789 221.795 1.00 122.05 ? 247 ILE C C   1 
ATOM   7664  O O   . ILE C 3 203 ? 159.125 167.414 220.725 1.00 122.05 ? 247 ILE C O   1 
ATOM   7665  C CB  . ILE C 3 203 ? 157.861 168.481 223.203 1.00 122.05 ? 247 ILE C CB  1 
ATOM   7666  C CG1 . ILE C 3 203 ? 157.855 169.223 224.542 1.00 122.05 ? 247 ILE C CG1 1 
ATOM   7667  C CG2 . ILE C 3 203 ? 156.571 167.698 223.017 1.00 122.05 ? 247 ILE C CG2 1 
ATOM   7668  C CD1 . ILE C 3 203 ? 157.833 168.308 225.747 1.00 122.05 ? 247 ILE C CD1 1 
ATOM   7669  N N   . PRO C 3 204 ? 159.089 165.455 221.815 1.00 152.48 ? 248 PRO C N   1 
ATOM   7670  C CA  . PRO C 3 204 ? 159.160 164.666 220.565 1.00 152.48 ? 248 PRO C CA  1 
ATOM   7671  C C   . PRO C 3 204 ? 157.853 164.672 219.776 1.00 152.48 ? 248 PRO C C   1 
ATOM   7672  O O   . PRO C 3 204 ? 157.046 163.743 219.806 1.00 152.48 ? 248 PRO C O   1 
ATOM   7673  C CB  . PRO C 3 204 ? 159.513 163.262 221.070 1.00 152.48 ? 248 PRO C CB  1 
ATOM   7674  C CG  . PRO C 3 204 ? 159.857 163.413 222.536 1.00 152.48 ? 248 PRO C CG  1 
ATOM   7675  C CD  . PRO C 3 204 ? 159.088 164.594 223.005 1.00 152.48 ? 248 PRO C CD  1 
ATOM   7676  N N   . ASP C 3 205 ? 157.629 165.765 219.041 1.00 193.41 ? 249 ASP C N   1 
ATOM   7677  C CA  . ASP C 3 205 ? 156.455 165.836 218.177 1.00 193.41 ? 249 ASP C CA  1 
ATOM   7678  C C   . ASP C 3 205 ? 156.610 164.943 216.954 1.00 193.41 ? 249 ASP C C   1 
ATOM   7679  O O   . ASP C 3 205 ? 155.612 164.431 216.432 1.00 193.41 ? 249 ASP C O   1 
ATOM   7680  C CB  . ASP C 3 205 ? 156.197 167.283 217.756 1.00 193.41 ? 249 ASP C CB  1 
ATOM   7681  C CG  . ASP C 3 205 ? 157.430 167.953 217.186 1.00 193.41 ? 249 ASP C CG  1 
ATOM   7682  O OD1 . ASP C 3 205 ? 157.636 167.875 215.957 1.00 193.41 ? 249 ASP C OD1 1 
ATOM   7683  O OD2 . ASP C 3 205 ? 158.194 168.557 217.969 1.00 193.41 ? 249 ASP C OD2 1 
ATOM   7684  N N   . SER C 3 206 ? 157.846 164.744 216.492 1.00 206.60 ? 250 SER C N   1 
ATOM   7685  C CA  . SER C 3 206 ? 158.169 163.814 215.410 1.00 206.60 ? 250 SER C CA  1 
ATOM   7686  C C   . SER C 3 206 ? 157.393 164.149 214.134 1.00 206.60 ? 250 SER C C   1 
ATOM   7687  O O   . SER C 3 206 ? 156.589 163.360 213.633 1.00 206.60 ? 250 SER C O   1 
ATOM   7688  C CB  . SER C 3 206 ? 157.923 162.366 215.848 1.00 206.60 ? 250 SER C CB  1 
ATOM   7689  O OG  . SER C 3 206 ? 159.007 161.876 216.618 1.00 206.60 ? 250 SER C OG  1 
ATOM   7690  N N   . GLN C 3 207 ? 157.651 165.348 213.611 1.00 162.73 ? 251 GLN C N   1 
ATOM   7691  C CA  . GLN C 3 207 ? 157.049 165.738 212.340 1.00 162.73 ? 251 GLN C CA  1 
ATOM   7692  C C   . GLN C 3 207 ? 157.888 165.246 211.163 1.00 162.73 ? 251 GLN C C   1 
ATOM   7693  O O   . GLN C 3 207 ? 157.350 164.864 210.119 1.00 162.73 ? 251 GLN C O   1 
ATOM   7694  C CB  . GLN C 3 207 ? 156.838 167.257 212.295 1.00 162.73 ? 251 GLN C CB  1 
ATOM   7695  C CG  . GLN C 3 207 ? 158.040 168.119 212.681 1.00 162.73 ? 251 GLN C CG  1 
ATOM   7696  C CD  . GLN C 3 207 ? 159.031 168.326 211.549 1.00 162.73 ? 251 GLN C CD  1 
ATOM   7697  O OE1 . GLN C 3 207 ? 158.765 167.974 210.400 1.00 162.73 ? 251 GLN C OE1 1 
ATOM   7698  N NE2 . GLN C 3 207 ? 160.174 168.924 211.868 1.00 162.73 ? 251 GLN C NE2 1 
ATOM   7699  N N   . THR C 3 208 ? 159.209 165.246 211.315 1.00 104.27 ? 252 THR C N   1 
ATOM   7700  C CA  . THR C 3 208 ? 160.110 164.648 210.341 1.00 104.27 ? 252 THR C CA  1 
ATOM   7701  C C   . THR C 3 208 ? 160.919 163.538 211.000 1.00 104.27 ? 252 THR C C   1 
ATOM   7702  O O   . THR C 3 208 ? 160.705 163.179 212.161 1.00 104.27 ? 252 THR C O   1 
ATOM   7703  C CB  . THR C 3 208 ? 161.045 165.698 209.727 1.00 104.27 ? 252 THR C CB  1 
ATOM   7704  O OG1 . THR C 3 208 ? 161.937 165.063 208.803 1.00 104.27 ? 252 THR C OG1 1 
ATOM   7705  C CG2 . THR C 3 208 ? 161.863 166.378 210.808 1.00 104.27 ? 252 THR C CG2 1 
ATOM   7706  N N   . LYS C 3 209 ? 161.856 162.987 210.234 1.00 56.84  ? 253 LYS C N   1 
ATOM   7707  C CA  . LYS C 3 209 ? 162.710 161.907 210.708 1.00 56.84  ? 253 LYS C CA  1 
ATOM   7708  C C   . LYS C 3 209 ? 164.185 162.278 210.726 1.00 56.84  ? 253 LYS C C   1 
ATOM   7709  O O   . LYS C 3 209 ? 164.850 162.113 211.753 1.00 56.84  ? 253 LYS C O   1 
ATOM   7710  C CB  . LYS C 3 209 ? 162.497 160.656 209.845 1.00 56.84  ? 253 LYS C CB  1 
ATOM   7711  C CG  . LYS C 3 209 ? 161.045 160.219 209.743 1.00 56.84  ? 253 LYS C CG  1 
ATOM   7712  C CD  . LYS C 3 209 ? 160.450 159.970 211.119 1.00 56.84  ? 253 LYS C CD  1 
ATOM   7713  C CE  . LYS C 3 209 ? 158.983 159.586 211.028 1.00 56.84  ? 253 LYS C CE  1 
ATOM   7714  N NZ  . LYS C 3 209 ? 158.389 159.335 212.369 1.00 56.84  ? 253 LYS C NZ  1 
ATOM   7715  N N   . VAL C 3 210 ? 164.714 162.784 209.617 1.00 33.96  ? 254 VAL C N   1 
ATOM   7716  C CA  . VAL C 3 210 ? 166.144 163.032 209.467 1.00 33.96  ? 254 VAL C CA  1 
ATOM   7717  C C   . VAL C 3 210 ? 166.438 164.496 209.756 1.00 33.96  ? 254 VAL C C   1 
ATOM   7718  O O   . VAL C 3 210 ? 165.686 165.389 209.346 1.00 33.96  ? 254 VAL C O   1 
ATOM   7719  C CB  . VAL C 3 210 ? 166.626 162.640 208.057 1.00 33.96  ? 254 VAL C CB  1 
ATOM   7720  C CG1 . VAL C 3 210 ? 168.143 162.719 207.966 1.00 33.96  ? 254 VAL C CG1 1 
ATOM   7721  C CG2 . VAL C 3 210 ? 166.138 161.246 207.704 1.00 33.96  ? 254 VAL C CG2 1 
ATOM   7722  N N   . PHE C 3 211 ? 167.537 164.743 210.469 1.00 34.20  ? 255 PHE C N   1 
ATOM   7723  C CA  . PHE C 3 211 ? 168.023 166.079 210.771 1.00 34.20  ? 255 PHE C CA  1 
ATOM   7724  C C   . PHE C 3 211 ? 169.486 166.193 210.364 1.00 34.20  ? 255 PHE C C   1 
ATOM   7725  O O   . PHE C 3 211 ? 170.257 165.245 210.555 1.00 34.20  ? 255 PHE C O   1 
ATOM   7726  C CB  . PHE C 3 211 ? 167.881 166.399 212.266 1.00 34.20  ? 255 PHE C CB  1 
ATOM   7727  C CG  . PHE C 3 211 ? 166.482 166.259 212.785 1.00 34.20  ? 255 PHE C CG  1 
ATOM   7728  C CD1 . PHE C 3 211 ? 165.601 167.325 212.732 1.00 34.20  ? 255 PHE C CD1 1 
ATOM   7729  C CD2 . PHE C 3 211 ? 166.048 165.064 213.330 1.00 34.20  ? 255 PHE C CD2 1 
ATOM   7730  C CE1 . PHE C 3 211 ? 164.313 167.201 213.211 1.00 34.20  ? 255 PHE C CE1 1 
ATOM   7731  C CE2 . PHE C 3 211 ? 164.760 164.932 213.810 1.00 34.20  ? 255 PHE C CE2 1 
ATOM   7732  C CZ  . PHE C 3 211 ? 163.891 166.002 213.751 1.00 34.20  ? 255 PHE C CZ  1 
ATOM   7733  N N   . PRO C 3 212 ? 169.904 167.338 209.802 1.00 36.99  ? 256 PRO C N   1 
ATOM   7734  C CA  . PRO C 3 212 ? 169.069 168.506 209.505 1.00 36.99  ? 256 PRO C CA  1 
ATOM   7735  C C   . PRO C 3 212 ? 168.325 168.379 208.178 1.00 36.99  ? 256 PRO C C   1 
ATOM   7736  O O   . PRO C 3 212 ? 168.187 167.274 207.653 1.00 36.99  ? 256 PRO C O   1 
ATOM   7737  C CB  . PRO C 3 212 ? 170.083 169.646 209.450 1.00 36.99  ? 256 PRO C CB  1 
ATOM   7738  C CG  . PRO C 3 212 ? 171.323 168.996 208.944 1.00 36.99  ? 256 PRO C CG  1 
ATOM   7739  C CD  . PRO C 3 212 ? 171.323 167.588 209.487 1.00 36.99  ? 256 PRO C CD  1 
ATOM   7740  N N   . GLN C 3 213 ? 167.853 169.504 207.644 1.00 43.16  ? 257 GLN C N   1 
ATOM   7741  C CA  . GLN C 3 213 ? 167.078 169.527 206.407 1.00 43.16  ? 257 GLN C CA  1 
ATOM   7742  C C   . GLN C 3 213 ? 167.589 170.658 205.525 1.00 43.16  ? 257 GLN C C   1 
ATOM   7743  O O   . GLN C 3 213 ? 167.402 171.835 205.851 1.00 43.16  ? 257 GLN C O   1 
ATOM   7744  C CB  . GLN C 3 213 ? 165.586 169.694 206.696 1.00 43.16  ? 257 GLN C CB  1 
ATOM   7745  C CG  . GLN C 3 213 ? 164.955 168.509 207.405 1.00 43.16  ? 257 GLN C CG  1 
ATOM   7746  C CD  . GLN C 3 213 ? 163.522 168.775 207.819 1.00 43.16  ? 257 GLN C CD  1 
ATOM   7747  O OE1 . GLN C 3 213 ? 162.705 167.858 207.893 1.00 43.16  ? 257 GLN C OE1 1 
ATOM   7748  N NE2 . GLN C 3 213 ? 163.210 170.035 208.095 1.00 43.16  ? 257 GLN C NE2 1 
ATOM   7749  N N   . ASP C 3 214 ? 168.229 170.297 204.411 1.00 34.24  ? 258 ASP C N   1 
ATOM   7750  C CA  . ASP C 3 214 ? 168.690 171.250 203.400 1.00 34.24  ? 258 ASP C CA  1 
ATOM   7751  C C   . ASP C 3 214 ? 169.646 172.284 204.000 1.00 34.24  ? 258 ASP C C   1 
ATOM   7752  O O   . ASP C 3 214 ? 169.381 173.487 204.013 1.00 34.24  ? 258 ASP C O   1 
ATOM   7753  C CB  . ASP C 3 214 ? 167.503 171.930 202.710 1.00 34.24  ? 258 ASP C CB  1 
ATOM   7754  C CG  . ASP C 3 214 ? 166.590 170.942 202.013 1.00 34.24  ? 258 ASP C CG  1 
ATOM   7755  O OD1 . ASP C 3 214 ? 167.093 169.911 201.521 1.00 34.24  ? 258 ASP C OD1 1 
ATOM   7756  O OD2 . ASP C 3 214 ? 165.368 171.196 201.958 1.00 34.24  ? 258 ASP C OD2 1 
ATOM   7757  N N   . LYS C 3 215 ? 170.773 171.789 204.501 1.00 82.10  ? 259 LYS C N   1 
ATOM   7758  C CA  . LYS C 3 215 ? 171.818 172.652 205.028 1.00 82.10  ? 259 LYS C CA  1 
ATOM   7759  C C   . LYS C 3 215 ? 172.857 172.946 203.954 1.00 82.10  ? 259 LYS C C   1 
ATOM   7760  O O   . LYS C 3 215 ? 173.051 172.166 203.017 1.00 82.10  ? 259 LYS C O   1 
ATOM   7761  C CB  . LYS C 3 215 ? 172.492 172.015 206.244 1.00 82.10  ? 259 LYS C CB  1 
ATOM   7762  C CG  . LYS C 3 215 ? 171.888 172.439 207.570 1.00 82.10  ? 259 LYS C CG  1 
ATOM   7763  C CD  . LYS C 3 215 ? 172.888 172.302 208.704 1.00 82.10  ? 259 LYS C CD  1 
ATOM   7764  C CE  . LYS C 3 215 ? 172.341 172.898 209.990 1.00 82.10  ? 259 LYS C CE  1 
ATOM   7765  N NZ  . LYS C 3 215 ? 172.059 174.353 209.849 1.00 82.10  ? 259 LYS C NZ  1 
ATOM   7766  N N   . VAL C 3 216 ? 173.522 174.086 204.097 1.00 61.22  ? 260 VAL C N   1 
ATOM   7767  C CA  . VAL C 3 216 ? 174.553 174.526 203.164 1.00 61.22  ? 260 VAL C CA  1 
ATOM   7768  C C   . VAL C 3 216 ? 175.874 174.551 203.920 1.00 61.22  ? 260 VAL C C   1 
ATOM   7769  O O   . VAL C 3 216 ? 176.143 175.483 204.688 1.00 61.22  ? 260 VAL C O   1 
ATOM   7770  C CB  . VAL C 3 216 ? 174.230 175.898 202.559 1.00 61.22  ? 260 VAL C CB  1 
ATOM   7771  C CG1 . VAL C 3 216 ? 175.141 176.182 201.375 1.00 61.22  ? 260 VAL C CG1 1 
ATOM   7772  C CG2 . VAL C 3 216 ? 172.768 175.963 202.144 1.00 61.22  ? 260 VAL C CG2 1 
ATOM   7773  N N   . ILE C 3 217 ? 176.700 173.531 203.704 1.00 30.79  ? 261 ILE C N   1 
ATOM   7774  C CA  . ILE C 3 217 ? 177.991 173.415 204.365 1.00 30.79  ? 261 ILE C CA  1 
ATOM   7775  C C   . ILE C 3 217 ? 179.080 173.369 203.300 1.00 30.79  ? 261 ILE C C   1 
ATOM   7776  O O   . ILE C 3 217 ? 178.825 173.100 202.124 1.00 30.79  ? 261 ILE C O   1 
ATOM   7777  C CB  . ILE C 3 217 ? 178.063 172.178 205.285 1.00 30.79  ? 261 ILE C CB  1 
ATOM   7778  C CG1 . ILE C 3 217 ? 178.982 172.448 206.478 1.00 30.79  ? 261 ILE C CG1 1 
ATOM   7779  C CG2 . ILE C 3 217 ? 178.522 170.950 204.511 1.00 30.79  ? 261 ILE C CG2 1 
ATOM   7780  C CD1 . ILE C 3 217 ? 178.923 171.380 207.546 1.00 30.79  ? 261 ILE C CD1 1 
ATOM   7781  N N   . LEU C 3 218 ? 180.307 173.649 203.727 1.00 28.94  ? 262 LEU C N   1 
ATOM   7782  C CA  . LEU C 3 218 ? 181.433 173.693 202.808 1.00 28.94  ? 262 LEU C CA  1 
ATOM   7783  C C   . LEU C 3 218 ? 181.983 172.293 202.555 1.00 28.94  ? 262 LEU C C   1 
ATOM   7784  O O   . LEU C 3 218 ? 181.891 171.401 203.403 1.00 28.94  ? 262 LEU C O   1 
ATOM   7785  C CB  . LEU C 3 218 ? 182.531 174.612 203.351 1.00 28.94  ? 262 LEU C CB  1 
ATOM   7786  C CG  . LEU C 3 218 ? 183.186 174.302 204.702 1.00 28.94  ? 262 LEU C CG  1 
ATOM   7787  C CD1 . LEU C 3 218 ? 184.385 173.370 204.559 1.00 28.94  ? 262 LEU C CD1 1 
ATOM   7788  C CD2 . LEU C 3 218 ? 183.585 175.591 205.406 1.00 28.94  ? 262 LEU C CD2 1 
ATOM   7789  N N   . VAL C 3 219 ? 182.556 172.109 201.367 1.00 36.03  ? 263 VAL C N   1 
ATOM   7790  C CA  . VAL C 3 219 ? 183.150 170.827 201.004 1.00 36.03  ? 263 VAL C CA  1 
ATOM   7791  C C   . VAL C 3 219 ? 184.426 170.629 201.811 1.00 36.03  ? 263 VAL C C   1 
ATOM   7792  O O   . VAL C 3 219 ? 185.378 171.411 201.698 1.00 36.03  ? 263 VAL C O   1 
ATOM   7793  C CB  . VAL C 3 219 ? 183.430 170.758 199.498 1.00 36.03  ? 263 VAL C CB  1 
ATOM   7794  C CG1 . VAL C 3 219 ? 184.175 169.477 199.156 1.00 36.03  ? 263 VAL C CG1 1 
ATOM   7795  C CG2 . VAL C 3 219 ? 182.131 170.847 198.714 1.00 36.03  ? 263 VAL C CG2 1 
ATOM   7796  N N   . GLY C 3 220 ? 184.451 169.582 202.629 1.00 82.10  ? 264 GLY C N   1 
ATOM   7797  C CA  . GLY C 3 220 ? 185.599 169.272 203.452 1.00 82.10  ? 264 GLY C CA  1 
ATOM   7798  C C   . GLY C 3 220 ? 185.395 169.415 204.944 1.00 82.10  ? 264 GLY C C   1 
ATOM   7799  O O   . GLY C 3 220 ? 186.378 169.344 205.692 1.00 82.10  ? 264 GLY C O   1 
ATOM   7800  N N   . SER C 3 221 ? 184.164 169.613 205.404 1.00 46.55  ? 265 SER C N   1 
ATOM   7801  C CA  . SER C 3 221 ? 183.878 169.790 206.816 1.00 46.55  ? 265 SER C CA  1 
ATOM   7802  C C   . SER C 3 221 ? 183.212 168.537 207.380 1.00 46.55  ? 265 SER C C   1 
ATOM   7803  O O   . SER C 3 221 ? 182.915 167.578 206.663 1.00 46.55  ? 265 SER C O   1 
ATOM   7804  C CB  . SER C 3 221 ? 183.000 171.024 207.032 1.00 46.55  ? 265 SER C CB  1 
ATOM   7805  O OG  . SER C 3 221 ? 181.961 171.082 206.070 1.00 46.55  ? 265 SER C OG  1 
ATOM   7806  N N   . ASP C 3 222 ? 182.975 168.552 208.687 1.00 51.14  ? 266 ASP C N   1 
ATOM   7807  C CA  . ASP C 3 222 ? 182.342 167.445 209.387 1.00 51.14  ? 266 ASP C CA  1 
ATOM   7808  C C   . ASP C 3 222 ? 180.869 167.753 209.615 1.00 51.14  ? 266 ASP C C   1 
ATOM   7809  O O   . ASP C 3 222 ? 180.505 168.880 209.963 1.00 51.14  ? 266 ASP C O   1 
ATOM   7810  C CB  . ASP C 3 222 ? 183.034 167.179 210.726 1.00 51.14  ? 266 ASP C CB  1 
ATOM   7811  C CG  . ASP C 3 222 ? 182.487 165.955 211.434 1.00 51.14  ? 266 ASP C CG  1 
ATOM   7812  O OD1 . ASP C 3 222 ? 181.778 165.155 210.789 1.00 51.14  ? 266 ASP C OD1 1 
ATOM   7813  O OD2 . ASP C 3 222 ? 182.765 165.793 212.641 1.00 51.14  ? 266 ASP C OD2 1 
ATOM   7814  N N   . ILE C 3 223 ? 180.026 166.745 209.418 1.00 82.10  ? 267 ILE C N   1 
ATOM   7815  C CA  . ILE C 3 223 ? 178.589 166.886 209.621 1.00 82.10  ? 267 ILE C CA  1 
ATOM   7816  C C   . ILE C 3 223 ? 178.040 165.554 210.108 1.00 82.10  ? 267 ILE C C   1 
ATOM   7817  O O   . ILE C 3 223 ? 178.346 164.497 209.549 1.00 82.10  ? 267 ILE C O   1 
ATOM   7818  C CB  . ILE C 3 223 ? 177.881 167.362 208.333 1.00 82.10  ? 267 ILE C CB  1 
ATOM   7819  C CG1 . ILE C 3 223 ? 176.362 167.341 208.513 1.00 82.10  ? 267 ILE C CG1 1 
ATOM   7820  C CG2 . ILE C 3 223 ? 178.307 166.523 207.136 1.00 82.10  ? 267 ILE C CG2 1 
ATOM   7821  C CD1 . ILE C 3 223 ? 175.606 167.959 207.361 1.00 82.10  ? 267 ILE C CD1 1 
ATOM   7822  N N   . THR C 3 224 ? 177.232 165.608 211.163 1.00 82.10  ? 268 THR C N   1 
ATOM   7823  C CA  . THR C 3 224 ? 176.655 164.422 211.782 1.00 82.10  ? 268 THR C CA  1 
ATOM   7824  C C   . THR C 3 224 ? 175.150 164.442 211.571 1.00 82.10  ? 268 THR C C   1 
ATOM   7825  O O   . THR C 3 224 ? 174.481 165.415 211.937 1.00 82.10  ? 268 THR C O   1 
ATOM   7826  C CB  . THR C 3 224 ? 176.986 164.363 213.275 1.00 82.10  ? 268 THR C CB  1 
ATOM   7827  O OG1 . THR C 3 224 ? 178.405 164.285 213.450 1.00 82.10  ? 268 THR C OG1 1 
ATOM   7828  C CG2 . THR C 3 224 ? 176.333 163.149 213.917 1.00 82.10  ? 268 THR C CG2 1 
ATOM   7829  N N   . PHE C 3 225 ? 174.622 163.375 210.983 1.00 31.82  ? 269 PHE C N   1 
ATOM   7830  C CA  . PHE C 3 225 ? 173.194 163.230 210.750 1.00 31.82  ? 269 PHE C CA  1 
ATOM   7831  C C   . PHE C 3 225 ? 172.562 162.375 211.840 1.00 31.82  ? 269 PHE C C   1 
ATOM   7832  O O   . PHE C 3 225 ? 173.242 161.651 212.572 1.00 31.82  ? 269 PHE C O   1 
ATOM   7833  C CB  . PHE C 3 225 ? 172.926 162.604 209.379 1.00 31.82  ? 269 PHE C CB  1 
ATOM   7834  C CG  . PHE C 3 225 ? 173.142 163.543 208.229 1.00 31.82  ? 269 PHE C CG  1 
ATOM   7835  C CD1 . PHE C 3 225 ? 172.086 164.264 207.700 1.00 31.82  ? 269 PHE C CD1 1 
ATOM   7836  C CD2 . PHE C 3 225 ? 174.400 163.700 207.674 1.00 31.82  ? 269 PHE C CD2 1 
ATOM   7837  C CE1 . PHE C 3 225 ? 172.281 165.128 206.641 1.00 31.82  ? 269 PHE C CE1 1 
ATOM   7838  C CE2 . PHE C 3 225 ? 174.602 164.562 206.614 1.00 31.82  ? 269 PHE C CE2 1 
ATOM   7839  C CZ  . PHE C 3 225 ? 173.540 165.277 206.097 1.00 31.82  ? 269 PHE C CZ  1 
ATOM   7840  N N   . CYS C 3 226 ? 171.240 162.470 211.940 1.00 37.28  ? 270 CYS C N   1 
ATOM   7841  C CA  . CYS C 3 226 ? 170.482 161.649 212.869 1.00 37.28  ? 270 CYS C CA  1 
ATOM   7842  C C   . CYS C 3 226 ? 169.136 161.318 212.243 1.00 37.28  ? 270 CYS C C   1 
ATOM   7843  O O   . CYS C 3 226 ? 168.717 161.930 211.258 1.00 37.28  ? 270 CYS C O   1 
ATOM   7844  C CB  . CYS C 3 226 ? 170.292 162.344 214.220 1.00 37.28  ? 270 CYS C CB  1 
ATOM   7845  S SG  . CYS C 3 226 ? 169.151 161.476 215.320 1.00 37.28  ? 270 CYS C SG  1 
ATOM   7846  N N   . CYS C 3 227 ? 168.458 160.337 212.832 1.00 54.55  ? 271 CYS C N   1 
ATOM   7847  C CA  . CYS C 3 227 ? 167.152 159.908 212.342 1.00 54.55  ? 271 CYS C CA  1 
ATOM   7848  C C   . CYS C 3 227 ? 166.358 159.368 213.521 1.00 54.55  ? 271 CYS C C   1 
ATOM   7849  O O   . CYS C 3 227 ? 166.648 158.273 214.014 1.00 54.55  ? 271 CYS C O   1 
ATOM   7850  C CB  . CYS C 3 227 ? 167.292 158.856 211.245 1.00 54.55  ? 271 CYS C CB  1 
ATOM   7851  S SG  . CYS C 3 227 ? 165.756 157.990 210.845 1.00 54.55  ? 271 CYS C SG  1 
ATOM   7852  N N   . VAL C 3 228 ? 165.368 160.130 213.972 1.00 51.72  ? 272 VAL C N   1 
ATOM   7853  C CA  . VAL C 3 228 ? 164.484 159.698 215.046 1.00 51.72  ? 272 VAL C CA  1 
ATOM   7854  C C   . VAL C 3 228 ? 163.367 158.851 214.450 1.00 51.72  ? 272 VAL C C   1 
ATOM   7855  O O   . VAL C 3 228 ? 162.761 159.220 213.436 1.00 51.72  ? 272 VAL C O   1 
ATOM   7856  C CB  . VAL C 3 228 ? 163.928 160.904 215.825 1.00 51.72  ? 272 VAL C CB  1 
ATOM   7857  C CG1 . VAL C 3 228 ? 163.134 161.834 214.915 1.00 51.72  ? 272 VAL C CG1 1 
ATOM   7858  C CG2 . VAL C 3 228 ? 163.066 160.431 216.987 1.00 51.72  ? 272 VAL C CG2 1 
ATOM   7859  N N   . SER C 3 229 ? 163.117 157.694 215.059 1.00 59.16  ? 273 SER C N   1 
ATOM   7860  C CA  . SER C 3 229 ? 162.092 156.785 214.569 1.00 59.16  ? 273 SER C CA  1 
ATOM   7861  C C   . SER C 3 229 ? 161.617 155.913 215.720 1.00 59.16  ? 273 SER C C   1 
ATOM   7862  O O   . SER C 3 229 ? 162.358 155.662 216.674 1.00 59.16  ? 273 SER C O   1 
ATOM   7863  C CB  . SER C 3 229 ? 162.608 155.909 213.421 1.00 59.16  ? 273 SER C CB  1 
ATOM   7864  O OG  . SER C 3 229 ? 163.330 156.668 212.466 1.00 59.16  ? 273 SER C OG  1 
ATOM   7865  N N   . GLN C 3 230 ? 160.370 155.456 215.617 1.00 60.82  ? 274 GLN C N   1 
ATOM   7866  C CA  . GLN C 3 230 ? 159.802 154.527 216.582 1.00 60.82  ? 274 GLN C CA  1 
ATOM   7867  C C   . GLN C 3 230 ? 159.831 153.084 216.099 1.00 60.82  ? 274 GLN C C   1 
ATOM   7868  O O   . GLN C 3 230 ? 159.575 152.175 216.896 1.00 60.82  ? 274 GLN C O   1 
ATOM   7869  C CB  . GLN C 3 230 ? 158.360 154.926 216.918 1.00 60.82  ? 274 GLN C CB  1 
ATOM   7870  C CG  . GLN C 3 230 ? 157.937 154.575 218.335 1.00 60.82  ? 274 GLN C CG  1 
ATOM   7871  C CD  . GLN C 3 230 ? 158.731 155.331 219.383 1.00 60.82  ? 274 GLN C CD  1 
ATOM   7872  O OE1 . GLN C 3 230 ? 159.178 156.454 219.149 1.00 60.82  ? 274 GLN C OE1 1 
ATOM   7873  N NE2 . GLN C 3 230 ? 158.911 154.716 220.546 1.00 60.82  ? 274 GLN C NE2 1 
ATOM   7874  N N   . GLU C 3 231 ? 160.135 152.854 214.826 1.00 61.80  ? 275 GLU C N   1 
ATOM   7875  C CA  . GLU C 3 231 ? 160.245 151.522 214.257 1.00 61.80  ? 275 GLU C CA  1 
ATOM   7876  C C   . GLU C 3 231 ? 161.711 151.183 214.018 1.00 61.80  ? 275 GLU C C   1 
ATOM   7877  O O   . GLU C 3 231 ? 162.575 152.062 213.965 1.00 61.80  ? 275 GLU C O   1 
ATOM   7878  C CB  . GLU C 3 231 ? 159.457 151.419 212.946 1.00 61.80  ? 275 GLU C CB  1 
ATOM   7879  C CG  . GLU C 3 231 ? 158.961 150.020 212.620 1.00 61.80  ? 275 GLU C CG  1 
ATOM   7880  C CD  . GLU C 3 231 ? 158.216 149.960 211.301 1.00 61.80  ? 275 GLU C CD  1 
ATOM   7881  O OE1 . GLU C 3 231 ? 158.235 150.964 210.559 1.00 61.80  ? 275 GLU C OE1 1 
ATOM   7882  O OE2 . GLU C 3 231 ? 157.610 148.908 211.006 1.00 61.80  ? 275 GLU C OE2 1 
ATOM   7883  N N   . LYS C 3 232 ? 161.983 149.889 213.876 1.00 45.42  ? 276 LYS C N   1 
ATOM   7884  C CA  . LYS C 3 232 ? 163.349 149.432 213.662 1.00 45.42  ? 276 LYS C CA  1 
ATOM   7885  C C   . LYS C 3 232 ? 163.858 149.877 212.296 1.00 45.42  ? 276 LYS C C   1 
ATOM   7886  O O   . LYS C 3 232 ? 163.115 149.893 211.311 1.00 45.42  ? 276 LYS C O   1 
ATOM   7887  C CB  . LYS C 3 232 ? 163.424 147.911 213.782 1.00 45.42  ? 276 LYS C CB  1 
ATOM   7888  C CG  . LYS C 3 232 ? 162.787 147.359 215.046 1.00 45.42  ? 276 LYS C CG  1 
ATOM   7889  C CD  . LYS C 3 232 ? 163.384 148.001 216.288 1.00 45.42  ? 276 LYS C CD  1 
ATOM   7890  C CE  . LYS C 3 232 ? 162.693 147.510 217.549 1.00 45.42  ? 276 LYS C CE  1 
ATOM   7891  N NZ  . LYS C 3 232 ? 163.245 148.156 218.772 1.00 45.42  ? 276 LYS C NZ  1 
ATOM   7892  N N   . VAL C 3 233 ? 165.135 150.239 212.243 1.00 33.23  ? 277 VAL C N   1 
ATOM   7893  C CA  . VAL C 3 233 ? 165.777 150.660 211.009 1.00 33.23  ? 277 VAL C CA  1 
ATOM   7894  C C   . VAL C 3 233 ? 166.737 149.563 210.556 1.00 33.23  ? 277 VAL C C   1 
ATOM   7895  O O   . VAL C 3 233 ? 167.034 148.621 211.290 1.00 33.23  ? 277 VAL C O   1 
ATOM   7896  C CB  . VAL C 3 233 ? 166.506 152.009 211.166 1.00 33.23  ? 277 VAL C CB  1 
ATOM   7897  C CG1 . VAL C 3 233 ? 165.526 153.094 211.582 1.00 33.23  ? 277 VAL C CG1 1 
ATOM   7898  C CG2 . VAL C 3 233 ? 167.635 151.886 212.177 1.00 33.23  ? 277 VAL C CG2 1 
ATOM   7899  N N   . LEU C 3 234 ? 167.225 149.696 209.323 1.00 22.80  ? 278 LEU C N   1 
ATOM   7900  C CA  . LEU C 3 234 ? 168.109 148.702 208.729 1.00 22.80  ? 278 LEU C CA  1 
ATOM   7901  C C   . LEU C 3 234 ? 169.515 149.241 208.499 1.00 22.80  ? 278 LEU C C   1 
ATOM   7902  O O   . LEU C 3 234 ? 170.485 148.665 208.999 1.00 22.80  ? 278 LEU C O   1 
ATOM   7903  C CB  . LEU C 3 234 ? 167.511 148.189 207.412 1.00 22.80  ? 278 LEU C CB  1 
ATOM   7904  C CG  . LEU C 3 234 ? 166.157 147.486 207.520 1.00 22.80  ? 278 LEU C CG  1 
ATOM   7905  C CD1 . LEU C 3 234 ? 165.726 146.939 206.168 1.00 22.80  ? 278 LEU C CD1 1 
ATOM   7906  C CD2 . LEU C 3 234 ? 166.207 146.379 208.561 1.00 22.80  ? 278 LEU C CD2 1 
ATOM   7907  N N   . SER C 3 235 ? 169.653 150.339 207.761 1.00 19.63  ? 279 SER C N   1 
ATOM   7908  C CA  . SER C 3 235 ? 170.965 150.889 207.446 1.00 19.63  ? 279 SER C CA  1 
ATOM   7909  C C   . SER C 3 235 ? 170.790 152.324 206.964 1.00 19.63  ? 279 SER C C   1 
ATOM   7910  O O   . SER C 3 235 ? 169.670 152.820 206.814 1.00 19.63  ? 279 SER C O   1 
ATOM   7911  C CB  . SER C 3 235 ? 171.688 150.036 206.400 1.00 19.63  ? 279 SER C CB  1 
ATOM   7912  O OG  . SER C 3 235 ? 171.357 150.453 205.087 1.00 19.63  ? 279 SER C OG  1 
ATOM   7913  N N   . ALA C 3 236 ? 171.917 152.988 206.723 1.00 20.02  ? 280 ALA C N   1 
ATOM   7914  C CA  . ALA C 3 236 ? 171.943 154.345 206.200 1.00 20.02  ? 280 ALA C CA  1 
ATOM   7915  C C   . ALA C 3 236 ? 172.829 154.384 204.965 1.00 20.02  ? 280 ALA C C   1 
ATOM   7916  O O   . ALA C 3 236 ? 173.917 153.800 204.955 1.00 20.02  ? 280 ALA C O   1 
ATOM   7917  C CB  . ALA C 3 236 ? 172.455 155.340 207.245 1.00 20.02  ? 280 ALA C CB  1 
ATOM   7918  N N   . LEU C 3 237 ? 172.363 155.076 203.928 1.00 25.35  ? 281 LEU C N   1 
ATOM   7919  C CA  . LEU C 3 237 ? 173.071 155.144 202.659 1.00 25.35  ? 281 LEU C CA  1 
ATOM   7920  C C   . LEU C 3 237 ? 173.279 156.594 202.253 1.00 25.35  ? 281 LEU C C   1 
ATOM   7921  O O   . LEU C 3 237 ? 172.367 157.418 202.367 1.00 25.35  ? 281 LEU C O   1 
ATOM   7922  C CB  . LEU C 3 237 ? 172.306 154.405 201.552 1.00 25.35  ? 281 LEU C CB  1 
ATOM   7923  C CG  . LEU C 3 237 ? 171.847 152.977 201.850 1.00 25.35  ? 281 LEU C CG  1 
ATOM   7924  C CD1 . LEU C 3 237 ? 171.147 152.379 200.640 1.00 25.35  ? 281 LEU C CD1 1 
ATOM   7925  C CD2 . LEU C 3 237 ? 173.021 152.112 202.273 1.00 25.35  ? 281 LEU C CD2 1 
ATOM   7926  N N   . ILE C 3 238 ? 174.480 156.896 201.781 1.00 35.49  ? 282 ILE C N   1 
ATOM   7927  C CA  . ILE C 3 238 ? 174.803 158.196 201.197 1.00 35.49  ? 282 ILE C CA  1 
ATOM   7928  C C   . ILE C 3 238 ? 175.060 157.951 199.713 1.00 35.49  ? 282 ILE C C   1 
ATOM   7929  O O   . ILE C 3 238 ? 176.176 157.649 199.282 1.00 35.49  ? 282 ILE C O   1 
ATOM   7930  C CB  . ILE C 3 238 ? 175.988 158.876 201.892 1.00 35.49  ? 282 ILE C CB  1 
ATOM   7931  C CG1 . ILE C 3 238 ? 177.188 157.929 202.015 1.00 35.49  ? 282 ILE C CG1 1 
ATOM   7932  C CG2 . ILE C 3 238 ? 175.580 159.390 203.260 1.00 35.49  ? 282 ILE C CG2 1 
ATOM   7933  C CD1 . ILE C 3 238 ? 178.449 158.602 202.513 1.00 35.49  ? 282 ILE C CD1 1 
ATOM   7934  N N   . GLY C 3 239 ? 174.010 158.081 198.908 1.00 54.19  ? 283 GLY C N   1 
ATOM   7935  C CA  . GLY C 3 239 ? 174.100 157.725 197.507 1.00 54.19  ? 283 GLY C CA  1 
ATOM   7936  C C   . GLY C 3 239 ? 174.227 156.227 197.322 1.00 54.19  ? 283 GLY C C   1 
ATOM   7937  O O   . GLY C 3 239 ? 173.265 155.485 197.542 1.00 54.19  ? 283 GLY C O   1 
ATOM   7938  N N   . HIS C 3 240 ? 175.412 155.770 196.918 1.00 45.94  ? 284 HIS C N   1 
ATOM   7939  C CA  . HIS C 3 240 ? 175.691 154.349 196.778 1.00 45.94  ? 284 HIS C CA  1 
ATOM   7940  C C   . HIS C 3 240 ? 176.587 153.801 197.880 1.00 45.94  ? 284 HIS C C   1 
ATOM   7941  O O   . HIS C 3 240 ? 176.804 152.586 197.930 1.00 45.94  ? 284 HIS C O   1 
ATOM   7942  C CB  . HIS C 3 240 ? 176.337 154.068 195.413 1.00 45.94  ? 284 HIS C CB  1 
ATOM   7943  C CG  . HIS C 3 240 ? 175.631 154.719 194.265 1.00 45.94  ? 284 HIS C CG  1 
ATOM   7944  N ND1 . HIS C 3 240 ? 174.539 154.153 193.643 1.00 45.94  ? 284 HIS C ND1 1 
ATOM   7945  C CD2 . HIS C 3 240 ? 175.859 155.892 193.628 1.00 45.94  ? 284 HIS C CD2 1 
ATOM   7946  C CE1 . HIS C 3 240 ? 174.127 154.947 192.672 1.00 45.94  ? 284 HIS C CE1 1 
ATOM   7947  N NE2 . HIS C 3 240 ? 174.911 156.010 192.642 1.00 45.94  ? 284 HIS C NE2 1 
ATOM   7948  N N   . THR C 3 241 ? 177.105 154.656 198.757 1.00 41.35  ? 285 THR C N   1 
ATOM   7949  C CA  . THR C 3 241 ? 178.016 154.235 199.811 1.00 41.35  ? 285 THR C CA  1 
ATOM   7950  C C   . THR C 3 241 ? 177.256 154.000 201.109 1.00 41.35  ? 285 THR C C   1 
ATOM   7951  O O   . THR C 3 241 ? 176.305 154.720 201.427 1.00 41.35  ? 285 THR C O   1 
ATOM   7952  C CB  . THR C 3 241 ? 179.106 155.287 200.028 1.00 41.35  ? 285 THR C CB  1 
ATOM   7953  O OG1 . THR C 3 241 ? 179.598 155.735 198.759 1.00 41.35  ? 285 THR C OG1 1 
ATOM   7954  C CG2 . THR C 3 241 ? 180.258 154.707 200.833 1.00 41.35  ? 285 THR C CG2 1 
ATOM   7955  N N   . ASN C 3 242 ? 177.680 152.983 201.855 1.00 42.80  ? 286 ASN C N   1 
ATOM   7956  C CA  . ASN C 3 242 ? 177.076 152.672 203.139 1.00 42.80  ? 286 ASN C CA  1 
ATOM   7957  C C   . ASN C 3 242 ? 177.742 153.478 204.253 1.00 42.80  ? 286 ASN C C   1 
ATOM   7958  O O   . ASN C 3 242 ? 178.747 154.164 204.049 1.00 42.80  ? 286 ASN C O   1 
ATOM   7959  C CB  . ASN C 3 242 ? 177.179 151.176 203.429 1.00 42.80  ? 286 ASN C CB  1 
ATOM   7960  C CG  . ASN C 3 242 ? 176.374 150.337 202.458 1.00 42.80  ? 286 ASN C CG  1 
ATOM   7961  O OD1 . ASN C 3 242 ? 176.732 150.206 201.287 1.00 42.80  ? 286 ASN C OD1 1 
ATOM   7962  N ND2 . ASN C 3 242 ? 175.282 149.757 202.941 1.00 42.80  ? 286 ASN C ND2 1 
ATOM   7963  N N   . CYS C 3 243 ? 177.164 153.384 205.452 1.00 52.75  ? 287 CYS C N   1 
ATOM   7964  C CA  . CYS C 3 243 ? 177.674 154.091 206.616 1.00 52.75  ? 287 CYS C CA  1 
ATOM   7965  C C   . CYS C 3 243 ? 177.389 153.274 207.866 1.00 52.75  ? 287 CYS C C   1 
ATOM   7966  O O   . CYS C 3 243 ? 176.325 152.643 207.955 1.00 52.75  ? 287 CYS C O   1 
ATOM   7967  C CB  . CYS C 3 243 ? 177.049 155.482 206.752 1.00 52.75  ? 287 CYS C CB  1 
ATOM   7968  S SG  . CYS C 3 243 ? 177.887 156.774 205.805 1.00 52.75  ? 287 CYS C SG  1 
ATOM   7969  N N   . PRO C 3 244 ? 178.302 153.260 208.836 1.00 82.10  ? 288 PRO C N   1 
ATOM   7970  C CA  . PRO C 3 244 ? 178.044 152.518 210.074 1.00 82.10  ? 288 PRO C CA  1 
ATOM   7971  C C   . PRO C 3 244 ? 177.056 153.256 210.964 1.00 82.10  ? 288 PRO C C   1 
ATOM   7972  O O   . PRO C 3 244 ? 177.081 154.484 211.068 1.00 82.10  ? 288 PRO C O   1 
ATOM   7973  C CB  . PRO C 3 244 ? 179.428 152.429 210.726 1.00 82.10  ? 288 PRO C CB  1 
ATOM   7974  C CG  . PRO C 3 244 ? 180.146 153.636 210.224 1.00 82.10  ? 288 PRO C CG  1 
ATOM   7975  C CD  . PRO C 3 244 ? 179.636 153.885 208.828 1.00 82.10  ? 288 PRO C CD  1 
ATOM   7976  N N   . LEU C 3 245 ? 176.181 152.490 211.610 1.00 30.80  ? 289 LEU C N   1 
ATOM   7977  C CA  . LEU C 3 245 ? 175.146 153.054 212.464 1.00 30.80  ? 289 LEU C CA  1 
ATOM   7978  C C   . LEU C 3 245 ? 175.638 153.168 213.901 1.00 30.80  ? 289 LEU C C   1 
ATOM   7979  O O   . LEU C 3 245 ? 176.379 152.311 214.389 1.00 30.80  ? 289 LEU C O   1 
ATOM   7980  C CB  . LEU C 3 245 ? 173.881 152.197 212.414 1.00 30.80  ? 289 LEU C CB  1 
ATOM   7981  C CG  . LEU C 3 245 ? 173.196 152.094 211.052 1.00 30.80  ? 289 LEU C CG  1 
ATOM   7982  C CD1 . LEU C 3 245 ? 171.925 151.268 211.155 1.00 30.80  ? 289 LEU C CD1 1 
ATOM   7983  C CD2 . LEU C 3 245 ? 172.897 153.478 210.500 1.00 30.80  ? 289 LEU C CD2 1 
ATOM   7984  N N   . ILE C 3 246 ? 175.218 154.236 214.572 1.00 27.34  ? 290 ILE C N   1 
ATOM   7985  C CA  . ILE C 3 246 ? 175.547 154.482 215.972 1.00 27.34  ? 290 ILE C CA  1 
ATOM   7986  C C   . ILE C 3 246 ? 174.244 154.434 216.758 1.00 27.34  ? 290 ILE C C   1 
ATOM   7987  O O   . ILE C 3 246 ? 173.401 155.332 216.637 1.00 27.34  ? 290 ILE C O   1 
ATOM   7988  C CB  . ILE C 3 246 ? 176.265 155.823 216.165 1.00 27.34  ? 290 ILE C CB  1 
ATOM   7989  C CG1 . ILE C 3 246 ? 177.558 155.859 215.349 1.00 27.34  ? 290 ILE C CG1 1 
ATOM   7990  C CG2 . ILE C 3 246 ? 176.555 156.063 217.639 1.00 27.34  ? 290 ILE C CG2 1 
ATOM   7991  C CD1 . ILE C 3 246 ? 178.316 157.163 215.464 1.00 27.34  ? 290 ILE C CD1 1 
ATOM   7992  N N   . HIS C 3 247 ? 174.076 153.389 217.564 1.00 25.90  ? 291 HIS C N   1 
ATOM   7993  C CA  . HIS C 3 247 ? 172.844 153.196 218.323 1.00 25.90  ? 291 HIS C CA  1 
ATOM   7994  C C   . HIS C 3 247 ? 172.763 154.226 219.443 1.00 25.90  ? 291 HIS C C   1 
ATOM   7995  O O   . HIS C 3 247 ? 173.512 154.152 220.422 1.00 25.90  ? 291 HIS C O   1 
ATOM   7996  C CB  . HIS C 3 247 ? 172.787 151.778 218.880 1.00 25.90  ? 291 HIS C CB  1 
ATOM   7997  C CG  . HIS C 3 247 ? 172.642 150.723 217.828 1.00 25.90  ? 291 HIS C CG  1 
ATOM   7998  N ND1 . HIS C 3 247 ? 171.418 150.220 217.442 1.00 25.90  ? 291 HIS C ND1 1 
ATOM   7999  C CD2 . HIS C 3 247 ? 173.567 150.075 217.081 1.00 25.90  ? 291 HIS C CD2 1 
ATOM   8000  C CE1 . HIS C 3 247 ? 171.596 149.308 216.503 1.00 25.90  ? 291 HIS C CE1 1 
ATOM   8001  N NE2 . HIS C 3 247 ? 172.891 149.201 216.265 1.00 25.90  ? 291 HIS C NE2 1 
ATOM   8002  N N   . LEU C 3 248 ? 171.854 155.186 219.300 1.00 41.20  ? 292 LEU C N   1 
ATOM   8003  C CA  . LEU C 3 248 ? 171.612 156.187 220.327 1.00 41.20  ? 292 LEU C CA  1 
ATOM   8004  C C   . LEU C 3 248 ? 170.504 155.698 221.259 1.00 41.20  ? 292 LEU C C   1 
ATOM   8005  O O   . LEU C 3 248 ? 170.110 154.529 221.233 1.00 41.20  ? 292 LEU C O   1 
ATOM   8006  C CB  . LEU C 3 248 ? 171.271 157.531 219.688 1.00 41.20  ? 292 LEU C CB  1 
ATOM   8007  C CG  . LEU C 3 248 ? 172.403 158.235 218.937 1.00 41.20  ? 292 LEU C CG  1 
ATOM   8008  C CD1 . LEU C 3 248 ? 171.910 159.531 218.315 1.00 41.20  ? 292 LEU C CD1 1 
ATOM   8009  C CD2 . LEU C 3 248 ? 173.578 158.497 219.866 1.00 41.20  ? 292 LEU C CD2 1 
ATOM   8010  N N   . ASP C 3 249 ? 169.996 156.593 222.104 1.00 60.40  ? 293 ASP C N   1 
ATOM   8011  C CA  . ASP C 3 249 ? 168.917 156.236 223.015 1.00 60.40  ? 293 ASP C CA  1 
ATOM   8012  C C   . ASP C 3 249 ? 167.667 155.853 222.234 1.00 60.40  ? 293 ASP C C   1 
ATOM   8013  O O   . ASP C 3 249 ? 167.219 156.590 221.351 1.00 60.40  ? 293 ASP C O   1 
ATOM   8014  C CB  . ASP C 3 249 ? 168.617 157.400 223.959 1.00 60.40  ? 293 ASP C CB  1 
ATOM   8015  C CG  . ASP C 3 249 ? 169.697 157.597 225.004 1.00 60.40  ? 293 ASP C CG  1 
ATOM   8016  O OD1 . ASP C 3 249 ? 170.269 156.588 225.465 1.00 60.40  ? 293 ASP C OD1 1 
ATOM   8017  O OD2 . ASP C 3 249 ? 169.975 158.760 225.363 1.00 60.40  ? 293 ASP C OD2 1 
ATOM   8018  N N   . GLY C 3 250 ? 167.106 154.691 222.562 1.00 62.05  ? 294 GLY C N   1 
ATOM   8019  C CA  . GLY C 3 250 ? 165.926 154.225 221.854 1.00 62.05  ? 294 GLY C CA  1 
ATOM   8020  C C   . GLY C 3 250 ? 166.286 153.669 220.490 1.00 62.05  ? 294 GLY C C   1 
ATOM   8021  O O   . GLY C 3 250 ? 167.333 153.040 220.300 1.00 62.05  ? 294 GLY C O   1 
ATOM   8022  N N   . GLU C 3 251 ? 165.405 153.905 219.520 1.00 44.56  ? 295 GLU C N   1 
ATOM   8023  C CA  . GLU C 3 251 ? 165.604 153.446 218.153 1.00 44.56  ? 295 GLU C CA  1 
ATOM   8024  C C   . GLU C 3 251 ? 166.322 154.474 217.288 1.00 44.56  ? 295 GLU C C   1 
ATOM   8025  O O   . GLU C 3 251 ? 166.448 154.267 216.077 1.00 44.56  ? 295 GLU C O   1 
ATOM   8026  C CB  . GLU C 3 251 ? 164.260 153.083 217.514 1.00 44.56  ? 295 GLU C CB  1 
ATOM   8027  C CG  . GLU C 3 251 ? 163.728 151.702 217.882 1.00 44.56  ? 295 GLU C CG  1 
ATOM   8028  C CD  . GLU C 3 251 ? 163.636 151.480 219.379 1.00 44.56  ? 295 GLU C CD  1 
ATOM   8029  O OE1 . GLU C 3 251 ? 164.137 150.442 219.860 1.00 44.56  ? 295 GLU C OE1 1 
ATOM   8030  O OE2 . GLU C 3 251 ? 163.064 152.344 220.075 1.00 44.56  ? 295 GLU C OE2 1 
ATOM   8031  N N   . ASN C 3 252 ? 166.793 155.568 217.878 1.00 44.95  ? 296 ASN C N   1 
ATOM   8032  C CA  . ASN C 3 252 ? 167.462 156.614 217.120 1.00 44.95  ? 296 ASN C CA  1 
ATOM   8033  C C   . ASN C 3 252 ? 168.870 156.180 216.736 1.00 44.95  ? 296 ASN C C   1 
ATOM   8034  O O   . ASN C 3 252 ? 169.587 155.567 217.532 1.00 44.95  ? 296 ASN C O   1 
ATOM   8035  C CB  . ASN C 3 252 ? 167.514 157.907 217.932 1.00 44.95  ? 296 ASN C CB  1 
ATOM   8036  C CG  . ASN C 3 252 ? 166.184 158.242 218.577 1.00 44.95  ? 296 ASN C CG  1 
ATOM   8037  O OD1 . ASN C 3 252 ? 165.126 157.842 218.090 1.00 44.95  ? 296 ASN C OD1 1 
ATOM   8038  N ND2 . ASN C 3 252 ? 166.230 158.979 219.681 1.00 44.95  ? 296 ASN C ND2 1 
ATOM   8039  N N   . VAL C 3 253 ? 169.263 156.503 215.504 1.00 32.34  ? 297 VAL C N   1 
ATOM   8040  C CA  . VAL C 3 253 ? 170.581 156.169 214.986 1.00 32.34  ? 297 VAL C CA  1 
ATOM   8041  C C   . VAL C 3 253 ? 171.232 157.435 214.447 1.00 32.34  ? 297 VAL C C   1 
ATOM   8042  O O   . VAL C 3 253 ? 170.562 158.413 214.109 1.00 32.34  ? 297 VAL C O   1 
ATOM   8043  C CB  . VAL C 3 253 ? 170.522 155.084 213.890 1.00 32.34  ? 297 VAL C CB  1 
ATOM   8044  C CG1 . VAL C 3 253 ? 169.985 153.781 214.460 1.00 32.34  ? 297 VAL C CG1 1 
ATOM   8045  C CG2 . VAL C 3 253 ? 169.667 155.553 212.725 1.00 32.34  ? 297 VAL C CG2 1 
ATOM   8046  N N   . ALA C 3 254 ? 172.561 157.404 214.372 1.00 28.06  ? 298 ALA C N   1 
ATOM   8047  C CA  . ALA C 3 254 ? 173.333 158.535 213.881 1.00 28.06  ? 298 ALA C CA  1 
ATOM   8048  C C   . ALA C 3 254 ? 174.502 158.025 213.052 1.00 28.06  ? 298 ALA C C   1 
ATOM   8049  O O   . ALA C 3 254 ? 174.969 156.897 213.222 1.00 28.06  ? 298 ALA C O   1 
ATOM   8050  C CB  . ALA C 3 254 ? 173.841 159.416 215.030 1.00 28.06  ? 298 ALA C CB  1 
ATOM   8051  N N   . ILE C 3 255 ? 174.974 158.880 212.142 1.00 22.05  ? 299 ILE C N   1 
ATOM   8052  C CA  . ILE C 3 255 ? 176.097 158.563 211.270 1.00 22.05  ? 299 ILE C CA  1 
ATOM   8053  C C   . ILE C 3 255 ? 177.024 159.769 211.203 1.00 22.05  ? 299 ILE C C   1 
ATOM   8054  O O   . ILE C 3 255 ? 176.623 160.907 211.457 1.00 22.05  ? 299 ILE C O   1 
ATOM   8055  C CB  . ILE C 3 255 ? 175.642 158.160 209.850 1.00 22.05  ? 299 ILE C CB  1 
ATOM   8056  C CG1 . ILE C 3 255 ? 174.677 159.202 209.283 1.00 22.05  ? 299 ILE C CG1 1 
ATOM   8057  C CG2 . ILE C 3 255 ? 174.998 156.782 209.865 1.00 22.05  ? 299 ILE C CG2 1 
ATOM   8058  C CD1 . ILE C 3 255 ? 174.141 158.853 207.911 1.00 22.05  ? 299 ILE C CD1 1 
ATOM   8059  N N   . LYS C 3 256 ? 178.279 159.505 210.854 1.00 45.57  ? 300 LYS C N   1 
ATOM   8060  C CA  . LYS C 3 256 ? 179.305 160.533 210.759 1.00 45.57  ? 300 LYS C CA  1 
ATOM   8061  C C   . LYS C 3 256 ? 179.864 160.576 209.345 1.00 45.57  ? 300 LYS C C   1 
ATOM   8062  O O   . LYS C 3 256 ? 180.078 159.533 208.719 1.00 45.57  ? 300 LYS C O   1 
ATOM   8063  C CB  . LYS C 3 256 ? 180.437 160.280 211.760 1.00 45.57  ? 300 LYS C CB  1 
ATOM   8064  C CG  . LYS C 3 256 ? 179.996 160.309 213.212 1.00 45.57  ? 300 LYS C CG  1 
ATOM   8065  C CD  . LYS C 3 256 ? 181.176 160.118 214.148 1.00 45.57  ? 300 LYS C CD  1 
ATOM   8066  C CE  . LYS C 3 256 ? 180.738 160.170 215.602 1.00 45.57  ? 300 LYS C CE  1 
ATOM   8067  N NZ  . LYS C 3 256 ? 181.883 159.975 216.533 1.00 45.57  ? 300 LYS C NZ  1 
ATOM   8068  N N   . ILE C 3 257 ? 180.098 161.787 208.846 1.00 36.93  ? 301 ILE C N   1 
ATOM   8069  C CA  . ILE C 3 257 ? 180.643 162.006 207.512 1.00 36.93  ? 301 ILE C CA  1 
ATOM   8070  C C   . ILE C 3 257 ? 181.855 162.916 207.643 1.00 36.93  ? 301 ILE C C   1 
ATOM   8071  O O   . ILE C 3 257 ? 181.750 164.019 208.192 1.00 36.93  ? 301 ILE C O   1 
ATOM   8072  C CB  . ILE C 3 257 ? 179.606 162.622 206.558 1.00 36.93  ? 301 ILE C CB  1 
ATOM   8073  C CG1 . ILE C 3 257 ? 178.372 161.723 206.458 1.00 36.93  ? 301 ILE C CG1 1 
ATOM   8074  C CG2 . ILE C 3 257 ? 180.217 162.852 205.184 1.00 36.93  ? 301 ILE C CG2 1 
ATOM   8075  C CD1 . ILE C 3 257 ? 177.277 162.285 205.579 1.00 36.93  ? 301 ILE C CD1 1 
ATOM   8076  N N   . ARG C 3 258 ? 182.999 162.460 207.139 1.00 42.09  ? 302 ARG C N   1 
ATOM   8077  C CA  . ARG C 3 258 ? 184.242 163.218 207.187 1.00 42.09  ? 302 ARG C CA  1 
ATOM   8078  C C   . ARG C 3 258 ? 184.722 163.487 205.769 1.00 42.09  ? 302 ARG C C   1 
ATOM   8079  O O   . ARG C 3 258 ? 184.784 162.566 204.947 1.00 42.09  ? 302 ARG C O   1 
ATOM   8080  C CB  . ARG C 3 258 ? 185.316 162.468 207.978 1.00 42.09  ? 302 ARG C CB  1 
ATOM   8081  C CG  . ARG C 3 258 ? 186.556 163.295 208.272 1.00 42.09  ? 302 ARG C CG  1 
ATOM   8082  C CD  . ARG C 3 258 ? 187.520 162.543 209.175 1.00 42.09  ? 302 ARG C CD  1 
ATOM   8083  N NE  . ARG C 3 258 ? 188.666 163.364 209.552 1.00 42.09  ? 302 ARG C NE  1 
ATOM   8084  C CZ  . ARG C 3 258 ? 189.655 162.949 210.338 1.00 42.09  ? 302 ARG C CZ  1 
ATOM   8085  N NH1 . ARG C 3 258 ? 190.659 163.765 210.629 1.00 42.09  ? 302 ARG C NH1 1 
ATOM   8086  N NH2 . ARG C 3 258 ? 189.640 161.719 210.831 1.00 42.09  ? 302 ARG C NH2 1 
ATOM   8087  N N   . ASN C 3 259 ? 185.063 164.747 205.492 1.00 54.34  ? 303 ASN C N   1 
ATOM   8088  C CA  . ASN C 3 259 ? 185.510 165.186 204.170 1.00 54.34  ? 303 ASN C CA  1 
ATOM   8089  C C   . ASN C 3 259 ? 184.484 164.813 203.097 1.00 54.34  ? 303 ASN C C   1 
ATOM   8090  O O   . ASN C 3 259 ? 184.754 164.037 202.178 1.00 54.34  ? 303 ASN C O   1 
ATOM   8091  C CB  . ASN C 3 259 ? 186.894 164.617 203.837 1.00 54.34  ? 303 ASN C CB  1 
ATOM   8092  C CG  . ASN C 3 259 ? 187.674 165.505 202.877 1.00 54.34  ? 303 ASN C CG  1 
ATOM   8093  O OD1 . ASN C 3 259 ? 187.423 166.707 202.815 1.00 54.34  ? 303 ASN C OD1 1 
ATOM   8094  N ND2 . ASN C 3 259 ? 188.620 164.929 202.122 1.00 54.34  ? 303 ASN C ND2 1 
ATOM   8095  N N   . ILE C 3 260 ? 183.286 165.383 203.242 1.00 34.39  ? 304 ILE C N   1 
ATOM   8096  C CA  . ILE C 3 260 ? 182.210 165.105 202.300 1.00 34.39  ? 304 ILE C CA  1 
ATOM   8097  C C   . ILE C 3 260 ? 182.594 165.610 200.916 1.00 34.39  ? 304 ILE C C   1 
ATOM   8098  O O   . ILE C 3 260 ? 183.174 166.693 200.762 1.00 34.39  ? 304 ILE C O   1 
ATOM   8099  C CB  . ILE C 3 260 ? 180.896 165.737 202.793 1.00 34.39  ? 304 ILE C CB  1 
ATOM   8100  C CG1 . ILE C 3 260 ? 179.783 165.557 201.759 1.00 34.39  ? 304 ILE C CG1 1 
ATOM   8101  C CG2 . ILE C 3 260 ? 181.099 167.208 203.130 1.00 34.39  ? 304 ILE C CG2 1 
ATOM   8102  C CD1 . ILE C 3 260 ? 178.454 166.138 202.187 1.00 34.39  ? 304 ILE C CD1 1 
ATOM   8103  N N   . SER C 3 261 ? 182.281 164.813 199.897 1.00 29.41  ? 305 SER C N   1 
ATOM   8104  C CA  . SER C 3 261 ? 182.631 165.161 198.529 1.00 29.41  ? 305 SER C CA  1 
ATOM   8105  C C   . SER C 3 261 ? 181.720 166.276 198.015 1.00 29.41  ? 305 SER C C   1 
ATOM   8106  O O   . SER C 3 261 ? 180.853 166.793 198.725 1.00 29.41  ? 305 SER C O   1 
ATOM   8107  C CB  . SER C 3 261 ? 182.546 163.928 197.633 1.00 29.41  ? 305 SER C CB  1 
ATOM   8108  O OG  . SER C 3 261 ? 181.363 163.192 197.890 1.00 29.41  ? 305 SER C OG  1 
ATOM   8109  N N   . VAL C 3 262 ? 181.923 166.646 196.751 1.00 31.90  ? 306 VAL C N   1 
ATOM   8110  C CA  . VAL C 3 262 ? 181.143 167.720 196.149 1.00 31.90  ? 306 VAL C CA  1 
ATOM   8111  C C   . VAL C 3 262 ? 179.722 167.239 195.890 1.00 31.90  ? 306 VAL C C   1 
ATOM   8112  O O   . VAL C 3 262 ? 179.500 166.119 195.409 1.00 31.90  ? 306 VAL C O   1 
ATOM   8113  C CB  . VAL C 3 262 ? 181.811 168.207 194.853 1.00 31.90  ? 306 VAL C CB  1 
ATOM   8114  C CG1 . VAL C 3 262 ? 181.166 169.498 194.374 1.00 31.90  ? 306 VAL C CG1 1 
ATOM   8115  C CG2 . VAL C 3 262 ? 183.305 168.396 195.066 1.00 31.90  ? 306 VAL C CG2 1 
ATOM   8116  N N   . SER C 3 263 ? 178.749 168.087 196.211 1.00 31.02  ? 307 SER C N   1 
ATOM   8117  C CA  . SER C 3 263 ? 177.352 167.737 196.011 1.00 31.02  ? 307 SER C CA  1 
ATOM   8118  C C   . SER C 3 263 ? 176.991 167.773 194.530 1.00 31.02  ? 307 SER C C   1 
ATOM   8119  O O   . SER C 3 263 ? 177.603 168.489 193.733 1.00 31.02  ? 307 SER C O   1 
ATOM   8120  C CB  . SER C 3 263 ? 176.447 168.687 196.792 1.00 31.02  ? 307 SER C CB  1 
ATOM   8121  O OG  . SER C 3 263 ? 175.081 168.419 196.531 1.00 31.02  ? 307 SER C OG  1 
ATOM   8122  N N   . ALA C 3 264 ? 175.981 166.988 194.168 1.00 34.08  ? 308 ALA C N   1 
ATOM   8123  C CA  . ALA C 3 264 ? 175.507 166.919 192.795 1.00 34.08  ? 308 ALA C CA  1 
ATOM   8124  C C   . ALA C 3 264 ? 174.437 167.987 192.569 1.00 34.08  ? 308 ALA C C   1 
ATOM   8125  O O   . ALA C 3 264 ? 174.235 168.882 193.394 1.00 34.08  ? 308 ALA C O   1 
ATOM   8126  C CB  . ALA C 3 264 ? 174.990 165.516 192.485 1.00 34.08  ? 308 ALA C CB  1 
ATOM   8127  N N   . SER C 3 265 ? 173.740 167.904 191.433 1.00 37.60  ? 309 SER C N   1 
ATOM   8128  C CA  . SER C 3 265 ? 172.693 168.876 191.134 1.00 37.60  ? 309 SER C CA  1 
ATOM   8129  C C   . SER C 3 265 ? 171.523 168.737 192.100 1.00 37.60  ? 309 SER C C   1 
ATOM   8130  O O   . SER C 3 265 ? 171.037 169.732 192.650 1.00 37.60  ? 309 SER C O   1 
ATOM   8131  C CB  . SER C 3 265 ? 172.220 168.708 189.689 1.00 37.60  ? 309 SER C CB  1 
ATOM   8132  O OG  . SER C 3 265 ? 171.194 167.735 189.600 1.00 37.60  ? 309 SER C OG  1 
ATOM   8133  N N   . SER C 3 266 ? 171.059 167.510 192.320 1.00 29.09  ? 310 SER C N   1 
ATOM   8134  C CA  . SER C 3 266 ? 169.959 167.247 193.236 1.00 29.09  ? 310 SER C CA  1 
ATOM   8135  C C   . SER C 3 266 ? 170.414 167.096 194.682 1.00 29.09  ? 310 SER C C   1 
ATOM   8136  O O   . SER C 3 266 ? 169.567 166.952 195.569 1.00 29.09  ? 310 SER C O   1 
ATOM   8137  C CB  . SER C 3 266 ? 169.201 165.988 192.803 1.00 29.09  ? 310 SER C CB  1 
ATOM   8138  O OG  . SER C 3 266 ? 168.326 165.543 193.825 1.00 29.09  ? 310 SER C OG  1 
ATOM   8139  N N   . GLY C 3 267 ? 171.712 167.122 194.938 1.00 27.20  ? 311 GLY C N   1 
ATOM   8140  C CA  . GLY C 3 267 ? 172.206 166.985 196.299 1.00 27.20  ? 311 GLY C CA  1 
ATOM   8141  C C   . GLY C 3 267 ? 172.403 165.538 196.702 1.00 27.20  ? 311 GLY C C   1 
ATOM   8142  O O   . GLY C 3 267 ? 171.714 164.629 196.242 1.00 27.20  ? 311 GLY C O   1 
ATOM   8143  N N   . THR C 3 268 ? 173.373 165.325 197.587 1.00 37.82  ? 312 THR C N   1 
ATOM   8144  C CA  . THR C 3 268 ? 173.701 163.989 198.084 1.00 37.82  ? 312 THR C CA  1 
ATOM   8145  C C   . THR C 3 268 ? 172.637 163.581 199.096 1.00 37.82  ? 312 THR C C   1 
ATOM   8146  O O   . THR C 3 268 ? 172.744 163.855 200.291 1.00 37.82  ? 312 THR C O   1 
ATOM   8147  C CB  . THR C 3 268 ? 175.094 163.969 198.701 1.00 37.82  ? 312 THR C CB  1 
ATOM   8148  O OG1 . THR C 3 268 ? 176.035 164.530 197.778 1.00 37.82  ? 312 THR C OG1 1 
ATOM   8149  C CG2 . THR C 3 268 ? 175.508 162.543 199.033 1.00 37.82  ? 312 THR C CG2 1 
ATOM   8150  N N   . ASN C 3 269 ? 171.594 162.915 198.608 1.00 27.11  ? 313 ASN C N   1 
ATOM   8151  C CA  . ASN C 3 269 ? 170.488 162.512 199.468 1.00 27.11  ? 313 ASN C CA  1 
ATOM   8152  C C   . ASN C 3 269 ? 170.936 161.410 200.422 1.00 27.11  ? 313 ASN C C   1 
ATOM   8153  O O   . ASN C 3 269 ? 171.350 160.330 199.987 1.00 27.11  ? 313 ASN C O   1 
ATOM   8154  C CB  . ASN C 3 269 ? 169.304 162.048 198.624 1.00 27.11  ? 313 ASN C CB  1 
ATOM   8155  C CG  . ASN C 3 269 ? 169.711 161.077 197.535 1.00 27.11  ? 313 ASN C CG  1 
ATOM   8156  O OD1 . ASN C 3 269 ? 170.812 161.161 196.993 1.00 27.11  ? 313 ASN C OD1 1 
ATOM   8157  N ND2 . ASN C 3 269 ? 168.820 160.148 197.209 1.00 27.11  ? 313 ASN C ND2 1 
ATOM   8158  N N   . VAL C 3 270 ? 170.855 161.685 201.719 1.00 23.19  ? 314 VAL C N   1 
ATOM   8159  C CA  . VAL C 3 270 ? 171.191 160.722 202.760 1.00 23.19  ? 314 VAL C CA  1 
ATOM   8160  C C   . VAL C 3 270 ? 169.886 160.118 203.262 1.00 23.19  ? 314 VAL C C   1 
ATOM   8161  O O   . VAL C 3 270 ? 169.075 160.805 203.891 1.00 23.19  ? 314 VAL C O   1 
ATOM   8162  C CB  . VAL C 3 270 ? 171.979 161.376 203.902 1.00 23.19  ? 314 VAL C CB  1 
ATOM   8163  C CG1 . VAL C 3 270 ? 172.447 160.323 204.893 1.00 23.19  ? 314 VAL C CG1 1 
ATOM   8164  C CG2 . VAL C 3 270 ? 173.157 162.162 203.349 1.00 23.19  ? 314 VAL C CG2 1 
ATOM   8165  N N   . VAL C 3 271 ? 169.680 158.833 202.989 1.00 17.55  ? 315 VAL C N   1 
ATOM   8166  C CA  . VAL C 3 271 ? 168.430 158.163 203.313 1.00 17.55  ? 315 VAL C CA  1 
ATOM   8167  C C   . VAL C 3 271 ? 168.673 157.126 204.402 1.00 17.55  ? 315 VAL C C   1 
ATOM   8168  O O   . VAL C 3 271 ? 169.783 156.617 204.587 1.00 17.55  ? 315 VAL C O   1 
ATOM   8169  C CB  . VAL C 3 271 ? 167.792 157.511 202.071 1.00 17.55  ? 315 VAL C CB  1 
ATOM   8170  C CG1 . VAL C 3 271 ? 167.696 158.519 200.940 1.00 17.55  ? 315 VAL C CG1 1 
ATOM   8171  C CG2 . VAL C 3 271 ? 168.591 156.294 201.639 1.00 17.55  ? 315 VAL C CG2 1 
ATOM   8172  N N   . PHE C 3 272 ? 167.606 156.817 205.136 1.00 23.76  ? 316 PHE C N   1 
ATOM   8173  C CA  . PHE C 3 272 ? 167.614 155.790 206.173 1.00 23.76  ? 316 PHE C CA  1 
ATOM   8174  C C   . PHE C 3 272 ? 166.553 154.759 205.813 1.00 23.76  ? 316 PHE C C   1 
ATOM   8175  O O   . PHE C 3 272 ? 165.354 155.031 205.929 1.00 23.76  ? 316 PHE C O   1 
ATOM   8176  C CB  . PHE C 3 272 ? 167.344 156.392 207.552 1.00 23.76  ? 316 PHE C CB  1 
ATOM   8177  C CG  . PHE C 3 272 ? 168.484 157.205 208.095 1.00 23.76  ? 316 PHE C CG  1 
ATOM   8178  C CD1 . PHE C 3 272 ? 169.389 156.647 208.981 1.00 23.76  ? 316 PHE C CD1 1 
ATOM   8179  C CD2 . PHE C 3 272 ? 168.646 158.530 207.725 1.00 23.76  ? 316 PHE C CD2 1 
ATOM   8180  C CE1 . PHE C 3 272 ? 170.436 157.393 209.485 1.00 23.76  ? 316 PHE C CE1 1 
ATOM   8181  C CE2 . PHE C 3 272 ? 169.692 159.280 208.225 1.00 23.76  ? 316 PHE C CE2 1 
ATOM   8182  C CZ  . PHE C 3 272 ? 170.588 158.711 209.106 1.00 23.76  ? 316 PHE C CZ  1 
ATOM   8183  N N   . THR C 3 273 ? 166.990 153.580 205.380 1.00 20.58  ? 317 THR C N   1 
ATOM   8184  C CA  . THR C 3 273 ? 166.060 152.541 204.965 1.00 20.58  ? 317 THR C CA  1 
ATOM   8185  C C   . THR C 3 273 ? 165.431 151.868 206.179 1.00 20.58  ? 317 THR C C   1 
ATOM   8186  O O   . THR C 3 273 ? 166.077 151.683 207.214 1.00 20.58  ? 317 THR C O   1 
ATOM   8187  C CB  . THR C 3 273 ? 166.764 151.502 204.090 1.00 20.58  ? 317 THR C CB  1 
ATOM   8188  O OG1 . THR C 3 273 ? 165.832 150.482 203.710 1.00 20.58  ? 317 THR C OG1 1 
ATOM   8189  C CG2 . THR C 3 273 ? 167.936 150.869 204.829 1.00 20.58  ? 317 THR C CG2 1 
ATOM   8190  N N   . THR C 3 274 ? 164.151 151.522 206.050 1.00 30.56  ? 318 THR C N   1 
ATOM   8191  C CA  . THR C 3 274 ? 163.423 150.852 207.120 1.00 30.56  ? 318 THR C CA  1 
ATOM   8192  C C   . THR C 3 274 ? 162.761 149.582 206.601 1.00 30.56  ? 318 THR C C   1 
ATOM   8193  O O   . THR C 3 274 ? 163.053 149.134 205.488 1.00 30.56  ? 318 THR C O   1 
ATOM   8194  C CB  . THR C 3 274 ? 162.371 151.779 207.736 1.00 30.56  ? 318 THR C CB  1 
ATOM   8195  O OG1 . THR C 3 274 ? 161.394 152.121 206.747 1.00 30.56  ? 318 THR C OG1 1 
ATOM   8196  C CG2 . THR C 3 274 ? 163.018 153.050 208.267 1.00 30.56  ? 318 THR C CG2 1 
ATOM   8197  N N   . GLU C 3 275 ? 161.876 148.994 207.408 1.00 61.25  ? 319 GLU C N   1 
ATOM   8198  C CA  . GLU C 3 275 ? 161.224 147.746 207.020 1.00 61.25  ? 319 GLU C CA  1 
ATOM   8199  C C   . GLU C 3 275 ? 160.362 147.932 205.776 1.00 61.25  ? 319 GLU C C   1 
ATOM   8200  O O   . GLU C 3 275 ? 160.533 147.225 204.777 1.00 61.25  ? 319 GLU C O   1 
ATOM   8201  C CB  . GLU C 3 275 ? 160.386 147.214 208.182 1.00 61.25  ? 319 GLU C CB  1 
ATOM   8202  C CG  . GLU C 3 275 ? 159.758 145.855 207.923 1.00 61.25  ? 319 GLU C CG  1 
ATOM   8203  C CD  . GLU C 3 275 ? 158.662 145.522 208.915 1.00 61.25  ? 319 GLU C CD  1 
ATOM   8204  O OE1 . GLU C 3 275 ? 157.491 145.863 208.645 1.00 61.25  ? 319 GLU C OE1 1 
ATOM   8205  O OE2 . GLU C 3 275 ? 158.970 144.920 209.964 1.00 61.25  ? 319 GLU C OE2 1 
ATOM   8206  N N   . ASP C 3 276 ? 159.427 148.884 205.818 1.00 60.24  ? 320 ASP C N   1 
ATOM   8207  C CA  . ASP C 3 276 ? 158.487 149.087 204.725 1.00 60.24  ? 320 ASP C CA  1 
ATOM   8208  C C   . ASP C 3 276 ? 158.579 150.453 204.062 1.00 60.24  ? 320 ASP C C   1 
ATOM   8209  O O   . ASP C 3 276 ? 158.065 150.609 202.950 1.00 60.24  ? 320 ASP C O   1 
ATOM   8210  C CB  . ASP C 3 276 ? 157.044 148.881 205.214 1.00 60.24  ? 320 ASP C CB  1 
ATOM   8211  C CG  . ASP C 3 276 ? 156.834 147.525 205.856 1.00 60.24  ? 320 ASP C CG  1 
ATOM   8212  O OD1 . ASP C 3 276 ? 157.520 146.562 205.452 1.00 60.24  ? 320 ASP C OD1 1 
ATOM   8213  O OD2 . ASP C 3 276 ? 155.983 147.422 206.764 1.00 60.24  ? 320 ASP C OD2 1 
ATOM   8214  N N   . ASN C 3 277 ? 159.211 151.437 204.699 1.00 47.70  ? 321 ASN C N   1 
ATOM   8215  C CA  . ASN C 3 277 ? 159.292 152.776 204.127 1.00 47.70  ? 321 ASN C CA  1 
ATOM   8216  C C   . ASN C 3 277 ? 160.738 153.244 204.042 1.00 47.70  ? 321 ASN C C   1 
ATOM   8217  O O   . ASN C 3 277 ? 161.665 152.464 204.280 1.00 47.70  ? 321 ASN C O   1 
ATOM   8218  C CB  . ASN C 3 277 ? 158.464 153.761 204.955 1.00 47.70  ? 321 ASN C CB  1 
ATOM   8219  C CG  . ASN C 3 277 ? 157.023 153.323 205.112 1.00 47.70  ? 321 ASN C CG  1 
ATOM   8220  O OD1 . ASN C 3 277 ? 156.450 152.701 204.218 1.00 47.70  ? 321 ASN C OD1 1 
ATOM   8221  N ND2 . ASN C 3 277 ? 156.428 153.645 206.255 1.00 47.70  ? 321 ASN C ND2 1 
ATOM   8222  N N   . ILE C 3 278 ? 160.938 154.513 203.703 1.00 34.21  ? 322 ILE C N   1 
ATOM   8223  C CA  . ILE C 3 278 ? 162.274 155.092 203.619 1.00 34.21  ? 322 ILE C CA  1 
ATOM   8224  C C   . ILE C 3 278 ? 162.168 156.586 203.888 1.00 34.21  ? 322 ILE C C   1 
ATOM   8225  O O   . ILE C 3 278 ? 161.253 157.257 203.400 1.00 34.21  ? 322 ILE C O   1 
ATOM   8226  C CB  . ILE C 3 278 ? 162.932 154.800 202.251 1.00 34.21  ? 322 ILE C CB  1 
ATOM   8227  C CG1 . ILE C 3 278 ? 164.336 155.405 202.187 1.00 34.21  ? 322 ILE C CG1 1 
ATOM   8228  C CG2 . ILE C 3 278 ? 162.059 155.298 201.106 1.00 34.21  ? 322 ILE C CG2 1 
ATOM   8229  C CD1 . ILE C 3 278 ? 165.166 154.896 201.032 1.00 34.21  ? 322 ILE C CD1 1 
ATOM   8230  N N   . PHE C 3 279 ? 163.099 157.102 204.686 1.00 36.19  ? 323 PHE C N   1 
ATOM   8231  C CA  . PHE C 3 279 ? 163.149 158.515 205.027 1.00 36.19  ? 323 PHE C CA  1 
ATOM   8232  C C   . PHE C 3 279 ? 164.535 159.057 204.719 1.00 36.19  ? 323 PHE C C   1 
ATOM   8233  O O   . PHE C 3 279 ? 165.535 158.349 204.873 1.00 36.19  ? 323 PHE C O   1 
ATOM   8234  C CB  . PHE C 3 279 ? 162.816 158.747 206.504 1.00 36.19  ? 323 PHE C CB  1 
ATOM   8235  C CG  . PHE C 3 279 ? 161.687 157.900 207.012 1.00 36.19  ? 323 PHE C CG  1 
ATOM   8236  C CD1 . PHE C 3 279 ? 160.371 158.260 206.774 1.00 36.19  ? 323 PHE C CD1 1 
ATOM   8237  C CD2 . PHE C 3 279 ? 161.940 156.744 207.731 1.00 36.19  ? 323 PHE C CD2 1 
ATOM   8238  C CE1 . PHE C 3 279 ? 159.328 157.482 207.241 1.00 36.19  ? 323 PHE C CE1 1 
ATOM   8239  C CE2 . PHE C 3 279 ? 160.902 155.963 208.202 1.00 36.19  ? 323 PHE C CE2 1 
ATOM   8240  C CZ  . PHE C 3 279 ? 159.594 156.332 207.956 1.00 36.19  ? 323 PHE C CZ  1 
ATOM   8241  N N   . GLY C 3 280 ? 164.590 160.309 204.283 1.00 34.25  ? 324 GLY C N   1 
ATOM   8242  C CA  . GLY C 3 280 ? 165.860 160.931 203.970 1.00 34.25  ? 324 GLY C CA  1 
ATOM   8243  C C   . GLY C 3 280 ? 165.685 162.397 203.653 1.00 34.25  ? 324 GLY C C   1 
ATOM   8244  O O   . GLY C 3 280 ? 164.574 162.871 203.393 1.00 34.25  ? 324 GLY C O   1 
ATOM   8245  N N   . THR C 3 281 ? 166.807 163.111 203.680 1.00 29.53  ? 325 THR C N   1 
ATOM   8246  C CA  . THR C 3 281 ? 166.852 164.531 203.367 1.00 29.53  ? 325 THR C CA  1 
ATOM   8247  C C   . THR C 3 281 ? 167.943 164.775 202.331 1.00 29.53  ? 325 THR C C   1 
ATOM   8248  O O   . THR C 3 281 ? 168.531 163.838 201.783 1.00 29.53  ? 325 THR C O   1 
ATOM   8249  C CB  . THR C 3 281 ? 167.096 165.373 204.626 1.00 29.53  ? 325 THR C CB  1 
ATOM   8250  O OG1 . THR C 3 281 ? 168.216 164.846 205.347 1.00 29.53  ? 325 THR C OG1 1 
ATOM   8251  C CG2 . THR C 3 281 ? 165.867 165.360 205.522 1.00 29.53  ? 325 THR C CG2 1 
ATOM   8252  N N   . VAL C 3 282 ? 168.212 166.049 202.062 1.00 18.68  ? 326 VAL C N   1 
ATOM   8253  C CA  . VAL C 3 282 ? 169.200 166.461 201.073 1.00 18.68  ? 326 VAL C CA  1 
ATOM   8254  C C   . VAL C 3 282 ? 170.189 167.403 201.744 1.00 18.68  ? 326 VAL C C   1 
ATOM   8255  O O   . VAL C 3 282 ? 169.787 168.306 202.487 1.00 18.68  ? 326 VAL C O   1 
ATOM   8256  C CB  . VAL C 3 282 ? 168.538 167.140 199.860 1.00 18.68  ? 326 VAL C CB  1 
ATOM   8257  C CG1 . VAL C 3 282 ? 169.577 167.470 198.804 1.00 18.68  ? 326 VAL C CG1 1 
ATOM   8258  C CG2 . VAL C 3 282 ? 167.447 166.252 199.281 1.00 18.68  ? 326 VAL C CG2 1 
ATOM   8259  N N   . ILE C 3 283 ? 171.477 167.189 201.487 1.00 82.10  ? 327 ILE C N   1 
ATOM   8260  C CA  . ILE C 3 283 ? 172.540 168.062 201.971 1.00 82.10  ? 327 ILE C CA  1 
ATOM   8261  C C   . ILE C 3 283 ? 173.206 168.715 200.768 1.00 82.10  ? 327 ILE C C   1 
ATOM   8262  O O   . ILE C 3 283 ? 173.403 168.074 199.729 1.00 82.10  ? 327 ILE C O   1 
ATOM   8263  C CB  . ILE C 3 283 ? 173.563 167.291 202.832 1.00 82.10  ? 327 ILE C CB  1 
ATOM   8264  C CG1 . ILE C 3 283 ? 174.682 168.219 203.311 1.00 82.10  ? 327 ILE C CG1 1 
ATOM   8265  C CG2 . ILE C 3 283 ? 174.137 166.111 202.069 1.00 82.10  ? 327 ILE C CG2 1 
ATOM   8266  C CD1 . ILE C 3 283 ? 174.208 169.328 204.220 1.00 82.10  ? 327 ILE C CD1 1 
ATOM   8267  N N   . PHE C 3 284 ? 173.538 169.997 200.904 1.00 32.68  ? 328 PHE C N   1 
ATOM   8268  C CA  . PHE C 3 284 ? 174.138 170.779 199.827 1.00 32.68  ? 328 PHE C CA  1 
ATOM   8269  C C   . PHE C 3 284 ? 175.538 171.200 200.252 1.00 32.68  ? 328 PHE C C   1 
ATOM   8270  O O   . PHE C 3 284 ? 175.694 172.040 201.145 1.00 32.68  ? 328 PHE C O   1 
ATOM   8271  C CB  . PHE C 3 284 ? 173.280 171.998 199.492 1.00 32.68  ? 328 PHE C CB  1 
ATOM   8272  C CG  . PHE C 3 284 ? 171.888 171.657 199.045 1.00 32.68  ? 328 PHE C CG  1 
ATOM   8273  C CD1 . PHE C 3 284 ? 171.628 171.346 197.722 1.00 32.68  ? 328 PHE C CD1 1 
ATOM   8274  C CD2 . PHE C 3 284 ? 170.839 171.654 199.948 1.00 32.68  ? 328 PHE C CD2 1 
ATOM   8275  C CE1 . PHE C 3 284 ? 170.347 171.034 197.307 1.00 32.68  ? 328 PHE C CE1 1 
ATOM   8276  C CE2 . PHE C 3 284 ? 169.556 171.343 199.540 1.00 32.68  ? 328 PHE C CE2 1 
ATOM   8277  C CZ  . PHE C 3 284 ? 169.310 171.033 198.218 1.00 32.68  ? 328 PHE C CZ  1 
ATOM   8278  N N   . ALA C 3 285 ? 176.550 170.620 199.615 1.00 31.14  ? 329 ALA C N   1 
ATOM   8279  C CA  . ALA C 3 285 ? 177.943 170.962 199.871 1.00 31.14  ? 329 ALA C CA  1 
ATOM   8280  C C   . ALA C 3 285 ? 178.420 171.925 198.792 1.00 31.14  ? 329 ALA C C   1 
ATOM   8281  O O   . ALA C 3 285 ? 178.356 171.608 197.600 1.00 31.14  ? 329 ALA C O   1 
ATOM   8282  C CB  . ALA C 3 285 ? 178.817 169.709 199.904 1.00 31.14  ? 329 ALA C CB  1 
ATOM   8283  N N   . GLY C 3 286 ? 178.896 173.096 199.210 1.00 48.10  ? 330 GLY C N   1 
ATOM   8284  C CA  . GLY C 3 286 ? 179.317 174.113 198.266 1.00 48.10  ? 330 GLY C CA  1 
ATOM   8285  C C   . GLY C 3 286 ? 180.706 174.658 198.522 1.00 48.10  ? 330 GLY C C   1 
ATOM   8286  O O   . GLY C 3 286 ? 181.513 174.031 199.214 1.00 48.10  ? 330 GLY C O   1 
ATOM   8287  N N   . TYR C 3 287 ? 180.994 175.828 197.969 1.00 52.56  ? 331 TYR C N   1 
ATOM   8288  C CA  . TYR C 3 287 ? 182.294 176.467 198.081 1.00 52.56  ? 331 TYR C CA  1 
ATOM   8289  C C   . TYR C 3 287 ? 182.093 177.957 198.306 1.00 52.56  ? 331 TYR C C   1 
ATOM   8290  O O   . TYR C 3 287 ? 181.055 178.513 197.932 1.00 52.56  ? 331 TYR C O   1 
ATOM   8291  C CB  . TYR C 3 287 ? 183.143 176.236 196.824 1.00 52.56  ? 331 TYR C CB  1 
ATOM   8292  C CG  . TYR C 3 287 ? 183.648 174.821 196.670 1.00 52.56  ? 331 TYR C CG  1 
ATOM   8293  C CD1 . TYR C 3 287 ? 184.836 174.420 197.267 1.00 52.56  ? 331 TYR C CD1 1 
ATOM   8294  C CD2 . TYR C 3 287 ? 182.941 173.887 195.925 1.00 52.56  ? 331 TYR C CD2 1 
ATOM   8295  C CE1 . TYR C 3 287 ? 185.304 173.128 197.129 1.00 52.56  ? 331 TYR C CE1 1 
ATOM   8296  C CE2 . TYR C 3 287 ? 183.401 172.592 195.780 1.00 52.56  ? 331 TYR C CE2 1 
ATOM   8297  C CZ  . TYR C 3 287 ? 184.583 172.218 196.385 1.00 52.56  ? 331 TYR C CZ  1 
ATOM   8298  O OH  . TYR C 3 287 ? 185.047 170.930 196.245 1.00 52.56  ? 331 TYR C OH  1 
ATOM   8299  N N   . PRO C 3 288 ? 183.063 178.628 198.922 1.00 67.40  ? 332 PRO C N   1 
ATOM   8300  C CA  . PRO C 3 288 ? 182.973 180.084 199.086 1.00 67.40  ? 332 PRO C CA  1 
ATOM   8301  C C   . PRO C 3 288 ? 183.019 180.783 197.740 1.00 67.40  ? 332 PRO C C   1 
ATOM   8302  O O   . PRO C 3 288 ? 183.534 180.226 196.759 1.00 67.40  ? 332 PRO C O   1 
ATOM   8303  C CB  . PRO C 3 288 ? 184.208 180.422 199.937 1.00 67.40  ? 332 PRO C CB  1 
ATOM   8304  C CG  . PRO C 3 288 ? 185.141 179.277 199.730 1.00 67.40  ? 332 PRO C CG  1 
ATOM   8305  C CD  . PRO C 3 288 ? 184.263 178.075 199.572 1.00 67.40  ? 332 PRO C CD  1 
ATOM   8306  N N   . PRO C 3 289 ? 182.491 182.003 197.648 1.00 50.63  ? 333 PRO C N   1 
ATOM   8307  C CA  . PRO C 3 289 ? 182.471 182.695 196.355 1.00 50.63  ? 333 PRO C CA  1 
ATOM   8308  C C   . PRO C 3 289 ? 183.855 183.187 195.964 1.00 50.63  ? 333 PRO C C   1 
ATOM   8309  O O   . PRO C 3 289 ? 184.585 183.763 196.775 1.00 50.63  ? 333 PRO C O   1 
ATOM   8310  C CB  . PRO C 3 289 ? 181.508 183.862 196.593 1.00 50.63  ? 333 PRO C CB  1 
ATOM   8311  C CG  . PRO C 3 289 ? 181.615 184.133 198.054 1.00 50.63  ? 333 PRO C CG  1 
ATOM   8312  C CD  . PRO C 3 289 ? 181.878 182.808 198.720 1.00 50.63  ? 333 PRO C CD  1 
ATOM   8313  N N   . ASP C 3 290 ? 184.211 182.953 194.705 1.00 59.98  ? 334 ASP C N   1 
ATOM   8314  C CA  . ASP C 3 290 ? 185.504 183.369 194.192 1.00 59.98  ? 334 ASP C CA  1 
ATOM   8315  C C   . ASP C 3 290 ? 185.523 184.875 193.940 1.00 59.98  ? 334 ASP C C   1 
ATOM   8316  O O   . ASP C 3 290 ? 184.485 185.515 193.747 1.00 59.98  ? 334 ASP C O   1 
ATOM   8317  C CB  . ASP C 3 290 ? 185.838 182.614 192.905 1.00 59.98  ? 334 ASP C CB  1 
ATOM   8318  C CG  . ASP C 3 290 ? 187.304 182.715 192.530 1.00 59.98  ? 334 ASP C CG  1 
ATOM   8319  O OD1 . ASP C 3 290 ? 188.089 183.268 193.329 1.00 59.98  ? 334 ASP C OD1 1 
ATOM   8320  O OD2 . ASP C 3 290 ? 187.672 182.242 191.434 1.00 59.98  ? 334 ASP C OD2 1 
ATOM   8321  N N   . THR C 3 291 ? 186.725 185.436 193.948 1.00 53.38  ? 335 THR C N   1 
ATOM   8322  C CA  . THR C 3 291 ? 186.885 186.858 193.669 1.00 53.38  ? 335 THR C CA  1 
ATOM   8323  C C   . THR C 3 291 ? 186.594 187.128 192.197 1.00 53.38  ? 335 THR C C   1 
ATOM   8324  O O   . THR C 3 291 ? 187.125 186.427 191.328 1.00 53.38  ? 335 THR C O   1 
ATOM   8325  C CB  . THR C 3 291 ? 188.299 187.317 194.021 1.00 53.38  ? 335 THR C CB  1 
ATOM   8326  O OG1 . THR C 3 291 ? 188.560 187.051 195.405 1.00 53.38  ? 335 THR C OG1 1 
ATOM   8327  C CG2 . THR C 3 291 ? 188.459 188.808 193.759 1.00 53.38  ? 335 THR C CG2 1 
ATOM   8328  N N   . PRO C 3 292 ? 185.757 188.114 191.877 1.00 35.41  ? 336 PRO C N   1 
ATOM   8329  C CA  . PRO C 3 292 ? 185.476 188.419 190.465 1.00 35.41  ? 336 PRO C CA  1 
ATOM   8330  C C   . PRO C 3 292 ? 186.733 188.873 189.740 1.00 35.41  ? 336 PRO C C   1 
ATOM   8331  O O   . PRO C 3 292 ? 187.340 189.890 190.086 1.00 35.41  ? 336 PRO C O   1 
ATOM   8332  C CB  . PRO C 3 292 ? 184.429 189.537 190.547 1.00 35.41  ? 336 PRO C CB  1 
ATOM   8333  C CG  . PRO C 3 292 ? 183.825 189.399 191.908 1.00 35.41  ? 336 PRO C CG  1 
ATOM   8334  C CD  . PRO C 3 292 ? 184.936 188.923 192.792 1.00 35.41  ? 336 PRO C CD  1 
ATOM   8335  N N   . GLN C 3 293 ? 187.122 188.108 188.727 1.00 36.15  ? 337 GLN C N   1 
ATOM   8336  C CA  . GLN C 3 293 ? 188.318 188.380 187.947 1.00 36.15  ? 337 GLN C CA  1 
ATOM   8337  C C   . GLN C 3 293 ? 187.956 189.046 186.625 1.00 36.15  ? 337 GLN C C   1 
ATOM   8338  O O   . GLN C 3 293 ? 186.830 188.935 186.133 1.00 36.15  ? 337 GLN C O   1 
ATOM   8339  C CB  . GLN C 3 293 ? 189.099 187.089 187.687 1.00 36.15  ? 337 GLN C CB  1 
ATOM   8340  C CG  . GLN C 3 293 ? 189.487 186.337 188.949 1.00 36.15  ? 337 GLN C CG  1 
ATOM   8341  C CD  . GLN C 3 293 ? 190.178 185.021 188.655 1.00 36.15  ? 337 GLN C CD  1 
ATOM   8342  O OE1 . GLN C 3 293 ? 190.352 184.644 187.496 1.00 36.15  ? 337 GLN C OE1 1 
ATOM   8343  N NE2 . GLN C 3 293 ? 190.577 184.314 189.706 1.00 36.15  ? 337 GLN C NE2 1 
ATOM   8344  N N   . GLN C 3 294 ? 188.938 189.748 186.055 1.00 37.77  ? 338 GLN C N   1 
ATOM   8345  C CA  . GLN C 3 294 ? 188.783 190.449 184.779 1.00 37.77  ? 338 GLN C CA  1 
ATOM   8346  C C   . GLN C 3 294 ? 187.632 191.451 184.837 1.00 37.77  ? 338 GLN C C   1 
ATOM   8347  O O   . GLN C 3 294 ? 186.785 191.518 183.944 1.00 37.77  ? 338 GLN C O   1 
ATOM   8348  C CB  . GLN C 3 294 ? 188.594 189.458 183.627 1.00 37.77  ? 338 GLN C CB  1 
ATOM   8349  C CG  . GLN C 3 294 ? 189.726 188.456 183.481 1.00 37.77  ? 338 GLN C CG  1 
ATOM   8350  C CD  . GLN C 3 294 ? 189.479 187.458 182.367 1.00 37.77  ? 338 GLN C CD  1 
ATOM   8351  O OE1 . GLN C 3 294 ? 188.452 187.508 181.691 1.00 37.77  ? 338 GLN C OE1 1 
ATOM   8352  N NE2 . GLN C 3 294 ? 190.421 186.544 182.172 1.00 37.77  ? 338 GLN C NE2 1 
ATOM   8353  N N   . LEU C 3 295 ? 187.606 192.239 185.909 1.00 40.42  ? 339 LEU C N   1 
ATOM   8354  C CA  . LEU C 3 295 ? 186.574 193.254 186.110 1.00 40.42  ? 339 LEU C CA  1 
ATOM   8355  C C   . LEU C 3 295 ? 187.044 194.546 185.453 1.00 40.42  ? 339 LEU C C   1 
ATOM   8356  O O   . LEU C 3 295 ? 187.842 195.292 186.024 1.00 40.42  ? 339 LEU C O   1 
ATOM   8357  C CB  . LEU C 3 295 ? 186.293 193.450 187.595 1.00 40.42  ? 339 LEU C CB  1 
ATOM   8358  C CG  . LEU C 3 295 ? 185.184 194.441 187.954 1.00 40.42  ? 339 LEU C CG  1 
ATOM   8359  C CD1 . LEU C 3 295 ? 183.843 193.959 187.426 1.00 40.42  ? 339 LEU C CD1 1 
ATOM   8360  C CD2 . LEU C 3 295 ? 185.124 194.661 189.457 1.00 40.42  ? 339 LEU C CD2 1 
ATOM   8361  N N   . ASN C 3 296 ? 186.551 194.810 184.245 1.00 43.98  ? 340 ASN C N   1 
ATOM   8362  C CA  . ASN C 3 296 ? 186.905 196.008 183.490 1.00 43.98  ? 340 ASN C CA  1 
ATOM   8363  C C   . ASN C 3 296 ? 185.630 196.621 182.929 1.00 43.98  ? 340 ASN C C   1 
ATOM   8364  O O   . ASN C 3 296 ? 184.954 196.005 182.099 1.00 43.98  ? 340 ASN C O   1 
ATOM   8365  C CB  . ASN C 3 296 ? 187.896 195.684 182.372 1.00 43.98  ? 340 ASN C CB  1 
ATOM   8366  C CG  . ASN C 3 296 ? 189.242 195.231 182.901 1.00 43.98  ? 340 ASN C CG  1 
ATOM   8367  O OD1 . ASN C 3 296 ? 190.151 196.039 183.091 1.00 43.98  ? 340 ASN C OD1 1 
ATOM   8368  N ND2 . ASN C 3 296 ? 189.375 193.932 183.145 1.00 43.98  ? 340 ASN C ND2 1 
ATOM   8369  N N   . CYS C 3 297 ? 185.304 197.829 183.381 1.00 54.91  ? 341 CYS C N   1 
ATOM   8370  C CA  . CYS C 3 297 ? 184.104 198.524 182.939 1.00 54.91  ? 341 CYS C CA  1 
ATOM   8371  C C   . CYS C 3 297 ? 184.443 199.513 181.833 1.00 54.91  ? 341 CYS C C   1 
ATOM   8372  O O   . CYS C 3 297 ? 185.490 200.166 181.865 1.00 54.91  ? 341 CYS C O   1 
ATOM   8373  C CB  . CYS C 3 297 ? 183.445 199.257 184.109 1.00 54.91  ? 341 CYS C CB  1 
ATOM   8374  S SG  . CYS C 3 297 ? 183.255 198.262 185.606 1.00 54.91  ? 341 CYS C SG  1 
ATOM   8375  N N   . GLU C 3 298 ? 183.549 199.618 180.853 1.00 58.36  ? 342 GLU C N   1 
ATOM   8376  C CA  . GLU C 3 298 ? 183.715 200.556 179.752 1.00 58.36  ? 342 GLU C CA  1 
ATOM   8377  C C   . GLU C 3 298 ? 182.336 200.974 179.258 1.00 58.36  ? 342 GLU C C   1 
ATOM   8378  O O   . GLU C 3 298 ? 181.308 200.475 179.726 1.00 58.36  ? 342 GLU C O   1 
ATOM   8379  C CB  . GLU C 3 298 ? 184.559 199.947 178.627 1.00 58.36  ? 342 GLU C CB  1 
ATOM   8380  C CG  . GLU C 3 298 ? 184.003 198.654 178.056 1.00 58.36  ? 342 GLU C CG  1 
ATOM   8381  C CD  . GLU C 3 298 ? 184.788 198.168 176.852 1.00 58.36  ? 342 GLU C CD  1 
ATOM   8382  O OE1 . GLU C 3 298 ? 185.349 199.015 176.126 1.00 58.36  ? 342 GLU C OE1 1 
ATOM   8383  O OE2 . GLU C 3 298 ? 184.844 196.940 176.633 1.00 58.36  ? 342 GLU C OE2 1 
ATOM   8384  N N   . THR C 3 299 ? 182.319 201.900 178.301 1.00 52.88  ? 343 THR C N   1 
ATOM   8385  C CA  . THR C 3 299 ? 181.077 202.437 177.767 1.00 52.88  ? 343 THR C CA  1 
ATOM   8386  C C   . THR C 3 299 ? 181.155 202.484 176.248 1.00 52.88  ? 343 THR C C   1 
ATOM   8387  O O   . THR C 3 299 ? 182.234 202.406 175.656 1.00 52.88  ? 343 THR C O   1 
ATOM   8388  C CB  . THR C 3 299 ? 180.778 203.837 178.319 1.00 52.88  ? 343 THR C CB  1 
ATOM   8389  O OG1 . THR C 3 299 ? 179.501 204.278 177.842 1.00 52.88  ? 343 THR C OG1 1 
ATOM   8390  C CG2 . THR C 3 299 ? 181.847 204.823 177.874 1.00 52.88  ? 343 THR C CG2 1 
ATOM   8391  N N   . HIS C 3 300 ? 179.987 202.617 175.622 1.00 49.93  ? 344 HIS C N   1 
ATOM   8392  C CA  . HIS C 3 300 ? 179.877 202.670 174.172 1.00 49.93  ? 344 HIS C CA  1 
ATOM   8393  C C   . HIS C 3 300 ? 179.378 204.003 173.640 1.00 49.93  ? 344 HIS C C   1 
ATOM   8394  O O   . HIS C 3 300 ? 179.756 204.385 172.530 1.00 49.93  ? 344 HIS C O   1 
ATOM   8395  C CB  . HIS C 3 300 ? 178.942 201.560 173.665 1.00 49.93  ? 344 HIS C CB  1 
ATOM   8396  C CG  . HIS C 3 300 ? 179.489 200.178 173.846 1.00 49.93  ? 344 HIS C CG  1 
ATOM   8397  N ND1 . HIS C 3 300 ? 180.240 199.543 172.881 1.00 49.93  ? 344 HIS C ND1 1 
ATOM   8398  C CD2 . HIS C 3 300 ? 179.394 199.310 174.881 1.00 49.93  ? 344 HIS C CD2 1 
ATOM   8399  C CE1 . HIS C 3 300 ? 180.585 198.343 173.313 1.00 49.93  ? 344 HIS C CE1 1 
ATOM   8400  N NE2 . HIS C 3 300 ? 180.084 198.177 174.524 1.00 49.93  ? 344 HIS C NE2 1 
ATOM   8401  N N   . ASP C 3 301 ? 178.542 204.722 174.395 1.00 55.90  ? 345 ASP C N   1 
ATOM   8402  C CA  . ASP C 3 301 ? 178.008 205.995 173.924 1.00 55.90  ? 345 ASP C CA  1 
ATOM   8403  C C   . ASP C 3 301 ? 178.014 207.065 175.012 1.00 55.90  ? 345 ASP C C   1 
ATOM   8404  O O   . ASP C 3 301 ? 177.305 208.069 174.880 1.00 55.90  ? 345 ASP C O   1 
ATOM   8405  C CB  . ASP C 3 301 ? 176.585 205.819 173.385 1.00 55.90  ? 345 ASP C CB  1 
ATOM   8406  C CG  . ASP C 3 301 ? 175.665 205.145 174.382 1.00 55.90  ? 345 ASP C CG  1 
ATOM   8407  O OD1 . ASP C 3 301 ? 176.169 204.397 175.246 1.00 55.90  ? 345 ASP C OD1 1 
ATOM   8408  O OD2 . ASP C 3 301 ? 174.438 205.362 174.302 1.00 55.90  ? 345 ASP C OD2 1 
ATOM   8409  N N   . LEU C 3 302 ? 178.791 206.871 176.080 1.00 54.82  ? 346 LEU C N   1 
ATOM   8410  C CA  . LEU C 3 302 ? 178.884 207.822 177.190 1.00 54.82  ? 346 LEU C CA  1 
ATOM   8411  C C   . LEU C 3 302 ? 177.533 208.044 177.866 1.00 54.82  ? 346 LEU C C   1 
ATOM   8412  O O   . LEU C 3 302 ? 177.258 209.128 178.388 1.00 54.82  ? 346 LEU C O   1 
ATOM   8413  C CB  . LEU C 3 302 ? 179.481 209.158 176.736 1.00 54.82  ? 346 LEU C CB  1 
ATOM   8414  C CG  . LEU C 3 302 ? 180.950 209.135 176.306 1.00 54.82  ? 346 LEU C CG  1 
ATOM   8415  C CD1 . LEU C 3 302 ? 181.415 210.527 175.911 1.00 54.82  ? 346 LEU C CD1 1 
ATOM   8416  C CD2 . LEU C 3 302 ? 181.824 208.569 177.413 1.00 54.82  ? 346 LEU C CD2 1 
ATOM   8417  N N   . LYS C 3 303 ? 176.686 207.027 177.866 1.00 70.63  ? 347 LYS C N   1 
ATOM   8418  C CA  . LYS C 3 303 ? 175.408 207.082 178.569 1.00 70.63  ? 347 LYS C CA  1 
ATOM   8419  C C   . LYS C 3 303 ? 175.213 205.923 179.533 1.00 70.63  ? 347 LYS C C   1 
ATOM   8420  O O   . LYS C 3 303 ? 174.636 206.116 180.606 1.00 70.63  ? 347 LYS C O   1 
ATOM   8421  C CB  . LYS C 3 303 ? 174.242 207.119 177.564 1.00 70.63  ? 347 LYS C CB  1 
ATOM   8422  C CG  . LYS C 3 303 ? 173.742 208.518 177.242 1.00 70.63  ? 347 LYS C CG  1 
ATOM   8423  C CD  . LYS C 3 303 ? 174.548 209.163 176.129 1.00 70.63  ? 347 LYS C CD  1 
ATOM   8424  C CE  . LYS C 3 303 ? 174.150 208.608 174.771 1.00 70.63  ? 347 LYS C CE  1 
ATOM   8425  N NZ  . LYS C 3 303 ? 174.862 209.296 173.659 1.00 70.63  ? 347 LYS C NZ  1 
ATOM   8426  N N   . GLU C 3 304 ? 175.677 204.726 179.181 1.00 70.83  ? 348 GLU C N   1 
ATOM   8427  C CA  . GLU C 3 304 ? 175.551 203.554 180.034 1.00 70.83  ? 348 GLU C CA  1 
ATOM   8428  C C   . GLU C 3 304 ? 176.922 202.932 180.248 1.00 70.83  ? 348 GLU C C   1 
ATOM   8429  O O   . GLU C 3 304 ? 177.798 203.006 179.382 1.00 70.83  ? 348 GLU C O   1 
ATOM   8430  C CB  . GLU C 3 304 ? 174.596 202.514 179.430 1.00 70.83  ? 348 GLU C CB  1 
ATOM   8431  C CG  . GLU C 3 304 ? 173.122 202.836 179.613 1.00 70.83  ? 348 GLU C CG  1 
ATOM   8432  C CD  . GLU C 3 304 ? 172.633 203.904 178.655 1.00 70.83  ? 348 GLU C CD  1 
ATOM   8433  O OE1 . GLU C 3 304 ? 172.291 205.011 179.120 1.00 70.83  ? 348 GLU C OE1 1 
ATOM   8434  O OE2 . GLU C 3 304 ? 172.591 203.636 177.436 1.00 70.83  ? 348 GLU C OE2 1 
ATOM   8435  N N   . ILE C 3 305 ? 177.100 202.316 181.413 1.00 58.29  ? 349 ILE C N   1 
ATOM   8436  C CA  . ILE C 3 305 ? 178.345 201.649 181.774 1.00 58.29  ? 349 ILE C CA  1 
ATOM   8437  C C   . ILE C 3 305 ? 178.069 200.152 181.822 1.00 58.29  ? 349 ILE C C   1 
ATOM   8438  O O   . ILE C 3 305 ? 177.420 199.659 182.752 1.00 58.29  ? 349 ILE C O   1 
ATOM   8439  C CB  . ILE C 3 305 ? 178.900 202.156 183.112 1.00 58.29  ? 349 ILE C CB  1 
ATOM   8440  C CG1 . ILE C 3 305 ? 179.251 203.640 183.011 1.00 58.29  ? 349 ILE C CG1 1 
ATOM   8441  C CG2 . ILE C 3 305 ? 180.123 201.348 183.522 1.00 58.29  ? 349 ILE C CG2 1 
ATOM   8442  C CD1 . ILE C 3 305 ? 179.863 204.212 184.270 1.00 58.29  ? 349 ILE C CD1 1 
ATOM   8443  N N   . ILE C 3 306 ? 178.558 199.430 180.819 1.00 57.63  ? 350 ILE C N   1 
ATOM   8444  C CA  . ILE C 3 306 ? 178.424 197.981 180.746 1.00 57.63  ? 350 ILE C CA  1 
ATOM   8445  C C   . ILE C 3 306 ? 179.731 197.366 181.225 1.00 57.63  ? 350 ILE C C   1 
ATOM   8446  O O   . ILE C 3 306 ? 180.785 197.569 180.610 1.00 57.63  ? 350 ILE C O   1 
ATOM   8447  C CB  . ILE C 3 306 ? 178.083 197.518 179.322 1.00 57.63  ? 350 ILE C CB  1 
ATOM   8448  C CG1 . ILE C 3 306 ? 176.774 198.157 178.855 1.00 57.63  ? 350 ILE C CG1 1 
ATOM   8449  C CG2 . ILE C 3 306 ? 177.993 196.001 179.263 1.00 57.63  ? 350 ILE C CG2 1 
ATOM   8450  C CD1 . ILE C 3 306 ? 176.385 197.789 177.440 1.00 57.63  ? 350 ILE C CD1 1 
ATOM   8451  N N   . CYS C 3 307 ? 179.667 196.614 182.321 1.00 56.04  ? 351 CYS C N   1 
ATOM   8452  C CA  . CYS C 3 307 ? 180.842 196.012 182.934 1.00 56.04  ? 351 CYS C CA  1 
ATOM   8453  C C   . CYS C 3 307 ? 180.665 194.503 183.002 1.00 56.04  ? 351 CYS C C   1 
ATOM   8454  O O   . CYS C 3 307 ? 179.595 194.015 183.380 1.00 56.04  ? 351 CYS C O   1 
ATOM   8455  C CB  . CYS C 3 307 ? 181.084 196.580 184.335 1.00 56.04  ? 351 CYS C CB  1 
ATOM   8456  S SG  . CYS C 3 307 ? 182.784 196.411 184.919 1.00 56.04  ? 351 CYS C SG  1 
ATOM   8457  N N   . SER C 3 308 ? 181.714 193.772 182.638 1.00 46.95  ? 352 SER C N   1 
ATOM   8458  C CA  . SER C 3 308 ? 181.713 192.319 182.663 1.00 46.95  ? 352 SER C CA  1 
ATOM   8459  C C   . SER C 3 308 ? 182.828 191.817 183.571 1.00 46.95  ? 352 SER C C   1 
ATOM   8460  O O   . SER C 3 308 ? 183.800 192.525 183.849 1.00 46.95  ? 352 SER C O   1 
ATOM   8461  C CB  . SER C 3 308 ? 181.882 191.738 181.253 1.00 46.95  ? 352 SER C CB  1 
ATOM   8462  O OG  . SER C 3 308 ? 182.895 192.425 180.538 1.00 46.95  ? 352 SER C OG  1 
ATOM   8463  N N   . TRP C 3 309 ? 182.676 190.578 184.034 1.00 42.42  ? 353 TRP C N   1 
ATOM   8464  C CA  . TRP C 3 309 ? 183.660 189.969 184.916 1.00 42.42  ? 353 TRP C CA  1 
ATOM   8465  C C   . TRP C 3 309 ? 183.573 188.455 184.796 1.00 42.42  ? 353 TRP C C   1 
ATOM   8466  O O   . TRP C 3 309 ? 182.563 187.903 184.351 1.00 42.42  ? 353 TRP C O   1 
ATOM   8467  C CB  . TRP C 3 309 ? 183.458 190.403 186.372 1.00 42.42  ? 353 TRP C CB  1 
ATOM   8468  C CG  . TRP C 3 309 ? 182.137 189.993 186.944 1.00 42.42  ? 353 TRP C CG  1 
ATOM   8469  C CD1 . TRP C 3 309 ? 181.865 188.851 187.638 1.00 42.42  ? 353 TRP C CD1 1 
ATOM   8470  C CD2 . TRP C 3 309 ? 180.907 190.723 186.874 1.00 42.42  ? 353 TRP C CD2 1 
ATOM   8471  N NE1 . TRP C 3 309 ? 180.541 188.824 188.004 1.00 42.42  ? 353 TRP C NE1 1 
ATOM   8472  C CE2 . TRP C 3 309 ? 179.931 189.962 187.549 1.00 42.42  ? 353 TRP C CE2 1 
ATOM   8473  C CE3 . TRP C 3 309 ? 180.535 191.946 186.308 1.00 42.42  ? 353 TRP C CE3 1 
ATOM   8474  C CZ2 . TRP C 3 309 ? 178.609 190.383 187.670 1.00 42.42  ? 353 TRP C CZ2 1 
ATOM   8475  C CZ3 . TRP C 3 309 ? 179.222 192.363 186.431 1.00 42.42  ? 353 TRP C CZ3 1 
ATOM   8476  C CH2 . TRP C 3 309 ? 178.275 191.583 187.106 1.00 42.42  ? 353 TRP C CH2 1 
ATOM   8477  N N   . ASN C 3 310 ? 184.653 187.788 185.202 1.00 35.54  ? 354 ASN C N   1 
ATOM   8478  C CA  . ASN C 3 310 ? 184.723 186.336 185.162 1.00 35.54  ? 354 ASN C CA  1 
ATOM   8479  C C   . ASN C 3 310 ? 184.643 185.788 186.576 1.00 35.54  ? 354 ASN C C   1 
ATOM   8480  O O   . ASN C 3 310 ? 185.482 186.151 187.416 1.00 35.54  ? 354 ASN C O   1 
ATOM   8481  C CB  . ASN C 3 310 ? 186.015 185.882 184.492 1.00 35.54  ? 354 ASN C CB  1 
ATOM   8482  C CG  . ASN C 3 310 ? 185.927 184.469 183.947 1.00 35.54  ? 354 ASN C CG  1 
ATOM   8483  O OD1 . ASN C 3 310 ? 185.334 183.587 184.567 1.00 35.54  ? 354 ASN C OD1 1 
ATOM   8484  N ND2 . ASN C 3 310 ? 186.520 184.249 182.780 1.00 35.54  ? 354 ASN C ND2 1 
ATOM   8485  N N   . PRO C 3 311 ? 183.671 184.927 186.891 1.00 45.10  ? 355 PRO C N   1 
ATOM   8486  C CA  . PRO C 3 311 ? 183.576 184.402 188.262 1.00 45.10  ? 355 PRO C CA  1 
ATOM   8487  C C   . PRO C 3 311 ? 184.683 183.426 188.620 1.00 45.10  ? 355 PRO C C   1 
ATOM   8488  O O   . PRO C 3 311 ? 184.924 183.206 189.813 1.00 45.10  ? 355 PRO C O   1 
ATOM   8489  C CB  . PRO C 3 311 ? 182.204 183.717 188.280 1.00 45.10  ? 355 PRO C CB  1 
ATOM   8490  C CG  . PRO C 3 311 ? 181.964 183.337 186.858 1.00 45.10  ? 355 PRO C CG  1 
ATOM   8491  C CD  . PRO C 3 311 ? 182.586 184.428 186.029 1.00 45.10  ? 355 PRO C CD  1 
ATOM   8492  N N   . GLY C 3 312 ? 185.359 182.838 187.638 1.00 57.80  ? 356 GLY C N   1 
ATOM   8493  C CA  . GLY C 3 312 ? 186.426 181.897 187.917 1.00 57.80  ? 356 GLY C CA  1 
ATOM   8494  C C   . GLY C 3 312 ? 185.925 180.542 188.372 1.00 57.80  ? 356 GLY C C   1 
ATOM   8495  O O   . GLY C 3 312 ? 185.186 179.869 187.647 1.00 57.80  ? 356 GLY C O   1 
ATOM   8496  N N   . ARG C 3 313 ? 186.326 180.129 189.572 1.00 52.09  ? 357 ARG C N   1 
ATOM   8497  C CA  . ARG C 3 313 ? 185.899 178.843 190.102 1.00 52.09  ? 357 ARG C CA  1 
ATOM   8498  C C   . ARG C 3 313 ? 184.406 178.860 190.408 1.00 52.09  ? 357 ARG C C   1 
ATOM   8499  O O   . ARG C 3 313 ? 183.877 179.833 190.952 1.00 52.09  ? 357 ARG C O   1 
ATOM   8500  C CB  . ARG C 3 313 ? 186.694 178.499 191.362 1.00 52.09  ? 357 ARG C CB  1 
ATOM   8501  C CG  . ARG C 3 313 ? 186.273 177.198 192.028 1.00 52.09  ? 357 ARG C CG  1 
ATOM   8502  C CD  . ARG C 3 313 ? 186.732 177.140 193.477 1.00 52.09  ? 357 ARG C CD  1 
ATOM   8503  N NE  . ARG C 3 313 ? 186.545 178.414 194.168 1.00 52.09  ? 357 ARG C NE  1 
ATOM   8504  C CZ  . ARG C 3 313 ? 185.373 178.871 194.597 1.00 52.09  ? 357 ARG C CZ  1 
ATOM   8505  N NH1 . ARG C 3 313 ? 184.269 178.160 194.409 1.00 52.09  ? 357 ARG C NH1 1 
ATOM   8506  N NH2 . ARG C 3 313 ? 185.303 180.041 195.215 1.00 52.09  ? 357 ARG C NH2 1 
ATOM   8507  N N   . VAL C 3 314 ? 183.725 177.770 190.048 1.00 48.71  ? 358 VAL C N   1 
ATOM   8508  C CA  . VAL C 3 314 ? 182.287 177.681 190.265 1.00 48.71  ? 358 VAL C CA  1 
ATOM   8509  C C   . VAL C 3 314 ? 181.990 177.569 191.757 1.00 48.71  ? 358 VAL C C   1 
ATOM   8510  O O   . VAL C 3 314 ? 182.827 177.124 192.554 1.00 48.71  ? 358 VAL C O   1 
ATOM   8511  C CB  . VAL C 3 314 ? 181.695 176.489 189.491 1.00 48.71  ? 358 VAL C CB  1 
ATOM   8512  C CG1 . VAL C 3 314 ? 181.875 176.689 187.995 1.00 48.71  ? 358 VAL C CG1 1 
ATOM   8513  C CG2 . VAL C 3 314 ? 182.343 175.190 189.942 1.00 48.71  ? 358 VAL C CG2 1 
ATOM   8514  N N   . THR C 3 315 ? 180.782 177.981 192.138 1.00 45.23  ? 359 THR C N   1 
ATOM   8515  C CA  . THR C 3 315 ? 180.348 177.933 193.528 1.00 45.23  ? 359 THR C CA  1 
ATOM   8516  C C   . THR C 3 315 ? 179.621 176.643 193.884 1.00 45.23  ? 359 THR C C   1 
ATOM   8517  O O   . THR C 3 315 ? 179.324 176.428 195.064 1.00 45.23  ? 359 THR C O   1 
ATOM   8518  C CB  . THR C 3 315 ? 179.436 179.124 193.840 1.00 45.23  ? 359 THR C CB  1 
ATOM   8519  O OG1 . THR C 3 315 ? 179.000 179.050 195.203 1.00 45.23  ? 359 THR C OG1 1 
ATOM   8520  C CG2 . THR C 3 315 ? 178.221 179.118 192.925 1.00 45.23  ? 359 THR C CG2 1 
ATOM   8521  N N   . ALA C 3 316 ? 179.322 175.795 192.898 1.00 54.53  ? 360 ALA C N   1 
ATOM   8522  C CA  . ALA C 3 316 ? 178.641 174.516 193.098 1.00 54.53  ? 360 ALA C CA  1 
ATOM   8523  C C   . ALA C 3 316 ? 177.272 174.676 193.752 1.00 54.53  ? 360 ALA C C   1 
ATOM   8524  O O   . ALA C 3 316 ? 176.764 173.735 194.371 1.00 54.53  ? 360 ALA C O   1 
ATOM   8525  C CB  . ALA C 3 316 ? 179.505 173.546 193.914 1.00 54.53  ? 360 ALA C CB  1 
ATOM   8526  N N   . LEU C 3 317 ? 176.659 175.851 193.627 1.00 44.90  ? 361 LEU C N   1 
ATOM   8527  C CA  . LEU C 3 317 ? 175.340 176.109 194.196 1.00 44.90  ? 361 LEU C CA  1 
ATOM   8528  C C   . LEU C 3 317 ? 174.498 176.829 193.157 1.00 44.90  ? 361 LEU C C   1 
ATOM   8529  O O   . LEU C 3 317 ? 174.844 177.937 192.736 1.00 44.90  ? 361 LEU C O   1 
ATOM   8530  C CB  . LEU C 3 317 ? 175.439 176.940 195.479 1.00 44.90  ? 361 LEU C CB  1 
ATOM   8531  C CG  . LEU C 3 317 ? 176.051 176.249 196.699 1.00 44.90  ? 361 LEU C CG  1 
ATOM   8532  C CD1 . LEU C 3 317 ? 176.115 177.204 197.880 1.00 44.90  ? 361 LEU C CD1 1 
ATOM   8533  C CD2 . LEU C 3 317 ? 175.264 174.999 197.060 1.00 44.90  ? 361 LEU C CD2 1 
ATOM   8534  N N   . VAL C 3 318 ? 173.395 176.203 192.747 1.00 40.23  ? 362 VAL C N   1 
ATOM   8535  C CA  . VAL C 3 318 ? 172.496 176.760 191.747 1.00 40.23  ? 362 VAL C CA  1 
ATOM   8536  C C   . VAL C 3 318 ? 171.074 176.729 192.294 1.00 40.23  ? 362 VAL C C   1 
ATOM   8537  O O   . VAL C 3 318 ? 170.805 176.184 193.365 1.00 40.23  ? 362 VAL C O   1 
ATOM   8538  C CB  . VAL C 3 318 ? 172.572 176.009 190.402 1.00 40.23  ? 362 VAL C CB  1 
ATOM   8539  C CG1 . VAL C 3 318 ? 173.975 176.100 189.820 1.00 40.23  ? 362 VAL C CG1 1 
ATOM   8540  C CG2 . VAL C 3 318 ? 172.153 174.559 190.583 1.00 40.23  ? 362 VAL C CG2 1 
ATOM   8541  N N   . GLY C 3 319 ? 170.160 177.326 191.535 1.00 47.48  ? 363 GLY C N   1 
ATOM   8542  C CA  . GLY C 3 319 ? 168.771 177.385 191.917 1.00 47.48  ? 363 GLY C CA  1 
ATOM   8543  C C   . GLY C 3 319 ? 168.486 178.544 192.849 1.00 47.48  ? 363 GLY C C   1 
ATOM   8544  O O   . GLY C 3 319 ? 168.973 179.662 192.656 1.00 47.48  ? 363 GLY C O   1 
ATOM   8545  N N   . PRO C 3 320 ? 167.682 178.296 193.888 1.00 41.87  ? 364 PRO C N   1 
ATOM   8546  C CA  . PRO C 3 320 ? 167.375 179.356 194.859 1.00 41.87  ? 364 PRO C CA  1 
ATOM   8547  C C   . PRO C 3 320 ? 168.543 179.736 195.755 1.00 41.87  ? 364 PRO C C   1 
ATOM   8548  O O   . PRO C 3 320 ? 168.366 180.578 196.643 1.00 41.87  ? 364 PRO C O   1 
ATOM   8549  C CB  . PRO C 3 320 ? 166.226 178.752 195.687 1.00 41.87  ? 364 PRO C CB  1 
ATOM   8550  C CG  . PRO C 3 320 ? 165.723 177.585 194.884 1.00 41.87  ? 364 PRO C CG  1 
ATOM   8551  C CD  . PRO C 3 320 ? 166.915 177.069 194.150 1.00 41.87  ? 364 PRO C CD  1 
ATOM   8552  N N   . ARG C 3 321 ? 169.725 179.150 195.560 1.00 39.98  ? 365 ARG C N   1 
ATOM   8553  C CA  . ARG C 3 321 ? 170.890 179.449 196.384 1.00 39.98  ? 365 ARG C CA  1 
ATOM   8554  C C   . ARG C 3 321 ? 172.087 179.847 195.528 1.00 39.98  ? 365 ARG C C   1 
ATOM   8555  O O   . ARG C 3 321 ? 173.237 179.659 195.932 1.00 39.98  ? 365 ARG C O   1 
ATOM   8556  C CB  . ARG C 3 321 ? 171.243 178.261 197.278 1.00 39.98  ? 365 ARG C CB  1 
ATOM   8557  C CG  . ARG C 3 321 ? 171.458 176.960 196.525 1.00 39.98  ? 365 ARG C CG  1 
ATOM   8558  C CD  . ARG C 3 321 ? 171.671 175.801 197.482 1.00 39.98  ? 365 ARG C CD  1 
ATOM   8559  N NE  . ARG C 3 321 ? 170.534 175.618 198.378 1.00 39.98  ? 365 ARG C NE  1 
ATOM   8560  C CZ  . ARG C 3 321 ? 169.479 174.860 198.100 1.00 39.98  ? 365 ARG C CZ  1 
ATOM   8561  N NH1 . ARG C 3 321 ? 169.413 174.209 196.947 1.00 39.98  ? 365 ARG C NH1 1 
ATOM   8562  N NH2 . ARG C 3 321 ? 168.489 174.752 198.975 1.00 39.98  ? 365 ARG C NH2 1 
ATOM   8563  N N   . ALA C 3 322 ? 171.833 180.396 194.343 1.00 42.09  ? 366 ALA C N   1 
ATOM   8564  C CA  . ALA C 3 322 ? 172.915 180.839 193.479 1.00 42.09  ? 366 ALA C CA  1 
ATOM   8565  C C   . ALA C 3 322 ? 173.544 182.118 194.018 1.00 42.09  ? 366 ALA C C   1 
ATOM   8566  O O   . ALA C 3 322 ? 172.912 182.894 194.739 1.00 42.09  ? 366 ALA C O   1 
ATOM   8567  C CB  . ALA C 3 322 ? 172.406 181.063 192.055 1.00 42.09  ? 366 ALA C CB  1 
ATOM   8568  N N   . THR C 3 323 ? 174.807 182.334 193.658 1.00 44.80  ? 367 THR C N   1 
ATOM   8569  C CA  . THR C 3 323 ? 175.535 183.507 194.125 1.00 44.80  ? 367 THR C CA  1 
ATOM   8570  C C   . THR C 3 323 ? 175.028 184.754 193.411 1.00 44.80  ? 367 THR C C   1 
ATOM   8571  O O   . THR C 3 323 ? 175.092 184.844 192.180 1.00 44.80  ? 367 THR C O   1 
ATOM   8572  C CB  . THR C 3 323 ? 177.033 183.328 193.891 1.00 44.80  ? 367 THR C CB  1 
ATOM   8573  O OG1 . THR C 3 323 ? 177.482 182.136 194.548 1.00 44.80  ? 367 THR C OG1 1 
ATOM   8574  C CG2 . THR C 3 323 ? 177.803 184.520 194.441 1.00 44.80  ? 367 THR C CG2 1 
ATOM   8575  N N   . SER C 3 324 ? 174.525 185.713 194.182 1.00 46.19  ? 368 SER C N   1 
ATOM   8576  C CA  . SER C 3 324 ? 174.003 186.962 193.645 1.00 46.19  ? 368 SER C CA  1 
ATOM   8577  C C   . SER C 3 324 ? 175.074 188.044 193.698 1.00 46.19  ? 368 SER C C   1 
ATOM   8578  O O   . SER C 3 324 ? 175.790 188.176 194.695 1.00 46.19  ? 368 SER C O   1 
ATOM   8579  C CB  . SER C 3 324 ? 172.764 187.413 194.422 1.00 46.19  ? 368 SER C CB  1 
ATOM   8580  O OG  . SER C 3 324 ? 171.885 186.326 194.656 1.00 46.19  ? 368 SER C OG  1 
ATOM   8581  N N   . TYR C 3 325 ? 175.176 188.816 192.621 1.00 37.70  ? 369 TYR C N   1 
ATOM   8582  C CA  . TYR C 3 325 ? 176.149 189.892 192.516 1.00 37.70  ? 369 TYR C CA  1 
ATOM   8583  C C   . TYR C 3 325 ? 175.469 191.235 192.747 1.00 37.70  ? 369 TYR C C   1 
ATOM   8584  O O   . TYR C 3 325 ? 174.309 191.429 192.370 1.00 37.70  ? 369 TYR C O   1 
ATOM   8585  C CB  . TYR C 3 325 ? 176.832 189.880 191.146 1.00 37.70  ? 369 TYR C CB  1 
ATOM   8586  C CG  . TYR C 3 325 ? 177.784 188.722 190.945 1.00 37.70  ? 369 TYR C CG  1 
ATOM   8587  C CD1 . TYR C 3 325 ? 179.136 188.852 191.233 1.00 37.70  ? 369 TYR C CD1 1 
ATOM   8588  C CD2 . TYR C 3 325 ? 177.331 187.500 190.468 1.00 37.70  ? 369 TYR C CD2 1 
ATOM   8589  C CE1 . TYR C 3 325 ? 180.011 187.798 191.051 1.00 37.70  ? 369 TYR C CE1 1 
ATOM   8590  C CE2 . TYR C 3 325 ? 178.198 186.439 190.283 1.00 37.70  ? 369 TYR C CE2 1 
ATOM   8591  C CZ  . TYR C 3 325 ? 179.536 186.594 190.576 1.00 37.70  ? 369 TYR C CZ  1 
ATOM   8592  O OH  . TYR C 3 325 ? 180.402 185.541 190.393 1.00 37.70  ? 369 TYR C OH  1 
ATOM   8593  N N   . THR C 3 326 ? 176.197 192.160 193.371 1.00 36.65  ? 370 THR C N   1 
ATOM   8594  C CA  . THR C 3 326 ? 175.671 193.483 193.689 1.00 36.65  ? 370 THR C CA  1 
ATOM   8595  C C   . THR C 3 326 ? 176.757 194.518 193.444 1.00 36.65  ? 370 THR C C   1 
ATOM   8596  O O   . THR C 3 326 ? 177.821 194.463 194.068 1.00 36.65  ? 370 THR C O   1 
ATOM   8597  C CB  . THR C 3 326 ? 175.183 193.552 195.139 1.00 36.65  ? 370 THR C CB  1 
ATOM   8598  O OG1 . THR C 3 326 ? 174.147 192.583 195.343 1.00 36.65  ? 370 THR C OG1 1 
ATOM   8599  C CG2 . THR C 3 326 ? 174.640 194.938 195.451 1.00 36.65  ? 370 THR C CG2 1 
ATOM   8600  N N   . LEU C 3 327 ? 176.487 195.456 192.541 1.00 42.16  ? 371 LEU C N   1 
ATOM   8601  C CA  . LEU C 3 327 ? 177.408 196.535 192.208 1.00 42.16  ? 371 LEU C CA  1 
ATOM   8602  C C   . LEU C 3 327 ? 176.866 197.835 192.788 1.00 42.16  ? 371 LEU C C   1 
ATOM   8603  O O   . LEU C 3 327 ? 175.735 198.229 192.484 1.00 42.16  ? 371 LEU C O   1 
ATOM   8604  C CB  . LEU C 3 327 ? 177.592 196.644 190.693 1.00 42.16  ? 371 LEU C CB  1 
ATOM   8605  C CG  . LEU C 3 327 ? 178.640 197.613 190.138 1.00 42.16  ? 371 LEU C CG  1 
ATOM   8606  C CD1 . LEU C 3 327 ? 179.208 197.076 188.836 1.00 42.16  ? 371 LEU C CD1 1 
ATOM   8607  C CD2 . LEU C 3 327 ? 178.041 198.993 189.913 1.00 42.16  ? 371 LEU C CD2 1 
ATOM   8608  N N   . VAL C 3 328 ? 177.672 198.497 193.614 1.00 44.24  ? 372 VAL C N   1 
ATOM   8609  C CA  . VAL C 3 328 ? 177.273 199.734 194.273 1.00 44.24  ? 372 VAL C CA  1 
ATOM   8610  C C   . VAL C 3 328 ? 178.268 200.831 193.918 1.00 44.24  ? 372 VAL C C   1 
ATOM   8611  O O   . VAL C 3 328 ? 179.459 200.579 193.707 1.00 44.24  ? 372 VAL C O   1 
ATOM   8612  C CB  . VAL C 3 328 ? 177.165 199.553 195.806 1.00 44.24  ? 372 VAL C CB  1 
ATOM   8613  C CG1 . VAL C 3 328 ? 178.540 199.372 196.433 1.00 44.24  ? 372 VAL C CG1 1 
ATOM   8614  C CG2 . VAL C 3 328 ? 176.431 200.728 196.440 1.00 44.24  ? 372 VAL C CG2 1 
ATOM   8615  N N   . GLU C 3 329 ? 177.760 202.057 193.830 1.00 52.26  ? 373 GLU C N   1 
ATOM   8616  C CA  . GLU C 3 329 ? 178.580 203.225 193.549 1.00 52.26  ? 373 GLU C CA  1 
ATOM   8617  C C   . GLU C 3 329 ? 179.166 203.782 194.841 1.00 52.26  ? 373 GLU C C   1 
ATOM   8618  O O   . GLU C 3 329 ? 178.550 203.709 195.908 1.00 52.26  ? 373 GLU C O   1 
ATOM   8619  C CB  . GLU C 3 329 ? 177.756 204.302 192.839 1.00 52.26  ? 373 GLU C CB  1 
ATOM   8620  C CG  . GLU C 3 329 ? 178.567 205.484 192.331 1.00 52.26  ? 373 GLU C CG  1 
ATOM   8621  C CD  . GLU C 3 329 ? 179.496 205.109 191.195 1.00 52.26  ? 373 GLU C CD  1 
ATOM   8622  O OE1 . GLU C 3 329 ? 179.178 204.155 190.455 1.00 52.26  ? 373 GLU C OE1 1 
ATOM   8623  O OE2 . GLU C 3 329 ? 180.546 205.768 191.043 1.00 52.26  ? 373 GLU C OE2 1 
ATOM   8624  N N   . SER C 3 330 ? 180.371 204.338 194.735 1.00 51.99  ? 374 SER C N   1 
ATOM   8625  C CA  . SER C 3 330 ? 181.057 204.896 195.894 1.00 51.99  ? 374 SER C CA  1 
ATOM   8626  C C   . SER C 3 330 ? 180.645 206.339 196.168 1.00 51.99  ? 374 SER C C   1 
ATOM   8627  O O   . SER C 3 330 ? 180.262 206.675 197.293 1.00 51.99  ? 374 SER C O   1 
ATOM   8628  C CB  . SER C 3 330 ? 182.573 204.812 195.695 1.00 51.99  ? 374 SER C CB  1 
ATOM   8629  O OG  . SER C 3 330 ? 182.983 205.583 194.580 1.00 51.99  ? 374 SER C OG  1 
ATOM   8630  N N   . PHE C 3 331 ? 180.715 207.202 195.152 1.00 51.03  ? 375 PHE C N   1 
ATOM   8631  C CA  . PHE C 3 331 ? 180.422 208.615 195.362 1.00 51.03  ? 375 PHE C CA  1 
ATOM   8632  C C   . PHE C 3 331 ? 178.926 208.875 195.485 1.00 51.03  ? 375 PHE C C   1 
ATOM   8633  O O   . PHE C 3 331 ? 178.517 209.802 196.192 1.00 51.03  ? 375 PHE C O   1 
ATOM   8634  C CB  . PHE C 3 331 ? 181.009 209.450 194.224 1.00 51.03  ? 375 PHE C CB  1 
ATOM   8635  C CG  . PHE C 3 331 ? 182.510 209.442 194.178 1.00 51.03  ? 375 PHE C CG  1 
ATOM   8636  C CD1 . PHE C 3 331 ? 183.252 209.180 195.318 1.00 51.03  ? 375 PHE C CD1 1 
ATOM   8637  C CD2 . PHE C 3 331 ? 183.180 209.698 192.993 1.00 51.03  ? 375 PHE C CD2 1 
ATOM   8638  C CE1 . PHE C 3 331 ? 184.633 209.172 195.277 1.00 51.03  ? 375 PHE C CE1 1 
ATOM   8639  C CE2 . PHE C 3 331 ? 184.561 209.692 192.945 1.00 51.03  ? 375 PHE C CE2 1 
ATOM   8640  C CZ  . PHE C 3 331 ? 185.288 209.429 194.089 1.00 51.03  ? 375 PHE C CZ  1 
ATOM   8641  N N   . SER C 3 332 ? 178.097 208.077 194.810 1.00 47.55  ? 376 SER C N   1 
ATOM   8642  C CA  . SER C 3 332 ? 176.658 208.292 194.805 1.00 47.55  ? 376 SER C CA  1 
ATOM   8643  C C   . SER C 3 332 ? 175.879 207.283 195.634 1.00 47.55  ? 376 SER C C   1 
ATOM   8644  O O   . SER C 3 332 ? 174.708 207.532 195.934 1.00 47.55  ? 376 SER C O   1 
ATOM   8645  C CB  . SER C 3 332 ? 176.122 208.267 193.366 1.00 47.55  ? 376 SER C CB  1 
ATOM   8646  O OG  . SER C 3 332 ? 176.955 209.022 192.503 1.00 47.55  ? 376 SER C OG  1 
ATOM   8647  N N   . GLY C 3 333 ? 176.489 206.160 196.008 1.00 57.02  ? 377 GLY C N   1 
ATOM   8648  C CA  . GLY C 3 333 ? 175.792 205.157 196.786 1.00 57.02  ? 377 GLY C CA  1 
ATOM   8649  C C   . GLY C 3 333 ? 174.735 204.380 196.038 1.00 57.02  ? 377 GLY C C   1 
ATOM   8650  O O   . GLY C 3 333 ? 174.035 203.569 196.652 1.00 57.02  ? 377 GLY C O   1 
ATOM   8651  N N   . LYS C 3 334 ? 174.593 204.599 194.733 1.00 46.72  ? 378 LYS C N   1 
ATOM   8652  C CA  . LYS C 3 334 ? 173.601 203.871 193.954 1.00 46.72  ? 378 LYS C CA  1 
ATOM   8653  C C   . LYS C 3 334 ? 174.050 202.430 193.748 1.00 46.72  ? 378 LYS C C   1 
ATOM   8654  O O   . LYS C 3 334 ? 175.213 202.171 193.423 1.00 46.72  ? 378 LYS C O   1 
ATOM   8655  C CB  . LYS C 3 334 ? 173.378 204.559 192.608 1.00 46.72  ? 378 LYS C CB  1 
ATOM   8656  C CG  . LYS C 3 334 ? 172.316 203.903 191.744 1.00 46.72  ? 378 LYS C CG  1 
ATOM   8657  C CD  . LYS C 3 334 ? 172.150 204.637 190.424 1.00 46.72  ? 378 LYS C CD  1 
ATOM   8658  C CE  . LYS C 3 334 ? 171.081 203.987 189.560 1.00 46.72  ? 378 LYS C CE  1 
ATOM   8659  N NZ  . LYS C 3 334 ? 170.910 204.696 188.262 1.00 46.72  ? 378 LYS C NZ  1 
ATOM   8660  N N   . TYR C 3 335 ? 173.126 201.491 193.937 1.00 48.21  ? 379 TYR C N   1 
ATOM   8661  C CA  . TYR C 3 335 ? 173.421 200.072 193.824 1.00 48.21  ? 379 TYR C CA  1 
ATOM   8662  C C   . TYR C 3 335 ? 172.463 199.420 192.839 1.00 48.21  ? 379 TYR C C   1 
ATOM   8663  O O   . TYR C 3 335 ? 171.334 199.879 192.647 1.00 48.21  ? 379 TYR C O   1 
ATOM   8664  C CB  . TYR C 3 335 ? 173.328 199.366 195.185 1.00 48.21  ? 379 TYR C CB  1 
ATOM   8665  C CG  . TYR C 3 335 ? 171.925 199.284 195.744 1.00 48.21  ? 379 TYR C CG  1 
ATOM   8666  C CD1 . TYR C 3 335 ? 171.339 200.378 196.366 1.00 48.21  ? 379 TYR C CD1 1 
ATOM   8667  C CD2 . TYR C 3 335 ? 171.188 198.109 195.654 1.00 48.21  ? 379 TYR C CD2 1 
ATOM   8668  C CE1 . TYR C 3 335 ? 170.057 200.307 196.879 1.00 48.21  ? 379 TYR C CE1 1 
ATOM   8669  C CE2 . TYR C 3 335 ? 169.906 198.029 196.164 1.00 48.21  ? 379 TYR C CE2 1 
ATOM   8670  C CZ  . TYR C 3 335 ? 169.346 199.130 196.776 1.00 48.21  ? 379 TYR C CZ  1 
ATOM   8671  O OH  . TYR C 3 335 ? 168.071 199.055 197.286 1.00 48.21  ? 379 TYR C OH  1 
ATOM   8672  N N   . VAL C 3 336 ? 172.928 198.339 192.216 1.00 40.77  ? 380 VAL C N   1 
ATOM   8673  C CA  . VAL C 3 336 ? 172.138 197.570 191.266 1.00 40.77  ? 380 VAL C CA  1 
ATOM   8674  C C   . VAL C 3 336 ? 172.325 196.088 191.559 1.00 40.77  ? 380 VAL C C   1 
ATOM   8675  O O   . VAL C 3 336 ? 173.406 195.646 191.962 1.00 40.77  ? 380 VAL C O   1 
ATOM   8676  C CB  . VAL C 3 336 ? 172.517 197.891 189.803 1.00 40.77  ? 380 VAL C CB  1 
ATOM   8677  C CG1 . VAL C 3 336 ? 172.025 199.278 189.420 1.00 40.77  ? 380 VAL C CG1 1 
ATOM   8678  C CG2 . VAL C 3 336 ? 174.021 197.791 189.613 1.00 40.77  ? 380 VAL C CG2 1 
ATOM   8679  N N   . ARG C 3 337 ? 171.258 195.319 191.356 1.00 41.79  ? 381 ARG C N   1 
ATOM   8680  C CA  . ARG C 3 337 ? 171.262 193.886 191.615 1.00 41.79  ? 381 ARG C CA  1 
ATOM   8681  C C   . ARG C 3 337 ? 170.817 193.138 190.368 1.00 41.79  ? 381 ARG C C   1 
ATOM   8682  O O   . ARG C 3 337 ? 169.861 193.542 189.698 1.00 41.79  ? 381 ARG C O   1 
ATOM   8683  C CB  . ARG C 3 337 ? 170.348 193.530 192.795 1.00 41.79  ? 381 ARG C CB  1 
ATOM   8684  C CG  . ARG C 3 337 ? 170.357 192.055 193.163 1.00 41.79  ? 381 ARG C CG  1 
ATOM   8685  C CD  . ARG C 3 337 ? 169.467 191.776 194.362 1.00 41.79  ? 381 ARG C CD  1 
ATOM   8686  N NE  . ARG C 3 337 ? 169.482 190.364 194.735 1.00 41.79  ? 381 ARG C NE  1 
ATOM   8687  C CZ  . ARG C 3 337 ? 168.819 189.857 195.769 1.00 41.79  ? 381 ARG C CZ  1 
ATOM   8688  N NH1 . ARG C 3 337 ? 168.084 190.646 196.540 1.00 41.79  ? 381 ARG C NH1 1 
ATOM   8689  N NH2 . ARG C 3 337 ? 168.892 188.560 196.034 1.00 41.79  ? 381 ARG C NH2 1 
ATOM   8690  N N   . LEU C 3 338 ? 171.515 192.048 190.061 1.00 46.74  ? 382 LEU C N   1 
ATOM   8691  C CA  . LEU C 3 338 ? 171.187 191.235 188.899 1.00 46.74  ? 382 LEU C CA  1 
ATOM   8692  C C   . LEU C 3 338 ? 170.009 190.318 189.206 1.00 46.74  ? 382 LEU C C   1 
ATOM   8693  O O   . LEU C 3 338 ? 169.858 189.830 190.329 1.00 46.74  ? 382 LEU C O   1 
ATOM   8694  C CB  . LEU C 3 338 ? 172.400 190.409 188.469 1.00 46.74  ? 382 LEU C CB  1 
ATOM   8695  C CG  . LEU C 3 338 ? 172.296 189.655 187.142 1.00 46.74  ? 382 LEU C CG  1 
ATOM   8696  C CD1 . LEU C 3 338 ? 172.024 190.620 185.999 1.00 46.74  ? 382 LEU C CD1 1 
ATOM   8697  C CD2 . LEU C 3 338 ? 173.562 188.855 186.881 1.00 46.74  ? 382 LEU C CD2 1 
ATOM   8698  N N   . LYS C 3 339 ? 169.174 190.086 188.196 1.00 72.28  ? 383 LYS C N   1 
ATOM   8699  C CA  . LYS C 3 339 ? 167.998 189.246 188.352 1.00 72.28  ? 383 LYS C CA  1 
ATOM   8700  C C   . LYS C 3 339 ? 168.390 187.769 188.309 1.00 72.28  ? 383 LYS C C   1 
ATOM   8701  O O   . LYS C 3 339 ? 169.566 187.410 188.196 1.00 72.28  ? 383 LYS C O   1 
ATOM   8702  C CB  . LYS C 3 339 ? 166.966 189.578 187.276 1.00 72.28  ? 383 LYS C CB  1 
ATOM   8703  C CG  . LYS C 3 339 ? 165.519 189.444 187.729 1.00 72.28  ? 383 LYS C CG  1 
ATOM   8704  C CD  . LYS C 3 339 ? 165.215 190.363 188.900 1.00 72.28  ? 383 LYS C CD  1 
ATOM   8705  C CE  . LYS C 3 339 ? 163.774 190.210 189.359 1.00 72.28  ? 383 LYS C CE  1 
ATOM   8706  N NZ  . LYS C 3 339 ? 163.478 188.821 189.805 1.00 72.28  ? 383 LYS C NZ  1 
ATOM   8707  N N   . ARG C 3 340 ? 167.383 186.896 188.402 1.00 81.50  ? 384 ARG C N   1 
ATOM   8708  C CA  . ARG C 3 340 ? 167.640 185.460 188.381 1.00 81.50  ? 384 ARG C CA  1 
ATOM   8709  C C   . ARG C 3 340 ? 168.090 184.985 187.006 1.00 81.50  ? 384 ARG C C   1 
ATOM   8710  O O   . ARG C 3 340 ? 168.897 184.053 186.907 1.00 81.50  ? 384 ARG C O   1 
ATOM   8711  C CB  . ARG C 3 340 ? 166.389 184.699 188.822 1.00 81.50  ? 384 ARG C CB  1 
ATOM   8712  C CG  . ARG C 3 340 ? 166.600 183.205 189.006 1.00 81.50  ? 384 ARG C CG  1 
ATOM   8713  C CD  . ARG C 3 340 ? 167.630 182.923 190.086 1.00 81.50  ? 384 ARG C CD  1 
ATOM   8714  N NE  . ARG C 3 340 ? 167.237 183.480 191.376 1.00 81.50  ? 384 ARG C NE  1 
ATOM   8715  C CZ  . ARG C 3 340 ? 167.989 183.431 192.471 1.00 81.50  ? 384 ARG C CZ  1 
ATOM   8716  N NH1 . ARG C 3 340 ? 169.180 182.850 192.433 1.00 81.50  ? 384 ARG C NH1 1 
ATOM   8717  N NH2 . ARG C 3 340 ? 167.551 183.964 193.603 1.00 81.50  ? 384 ARG C NH2 1 
ATOM   8718  N N   . ALA C 3 341 ? 167.586 185.604 185.941 1.00 103.31 ? 385 ALA C N   1 
ATOM   8719  C CA  . ALA C 3 341 ? 167.948 185.211 184.583 1.00 103.31 ? 385 ALA C CA  1 
ATOM   8720  C C   . ALA C 3 341 ? 169.409 185.560 184.326 1.00 103.31 ? 385 ALA C C   1 
ATOM   8721  O O   . ALA C 3 341 ? 169.768 186.739 184.242 1.00 103.31 ? 385 ALA C O   1 
ATOM   8722  C CB  . ALA C 3 341 ? 167.034 185.897 183.573 1.00 103.31 ? 385 ALA C CB  1 
ATOM   8723  N N   . GLU C 3 342 ? 170.251 184.539 184.199 1.00 132.54 ? 386 GLU C N   1 
ATOM   8724  C CA  . GLU C 3 342 ? 171.675 184.715 183.970 1.00 132.54 ? 386 GLU C CA  1 
ATOM   8725  C C   . GLU C 3 342 ? 172.026 184.382 182.526 1.00 132.54 ? 386 GLU C C   1 
ATOM   8726  O O   . GLU C 3 342 ? 171.269 183.718 181.812 1.00 132.54 ? 386 GLU C O   1 
ATOM   8727  C CB  . GLU C 3 342 ? 172.499 183.843 184.925 1.00 132.54 ? 386 GLU C CB  1 
ATOM   8728  C CG  . GLU C 3 342 ? 172.370 182.349 184.675 1.00 132.54 ? 386 GLU C CG  1 
ATOM   8729  C CD  . GLU C 3 342 ? 172.974 181.519 185.791 1.00 132.54 ? 386 GLU C CD  1 
ATOM   8730  O OE1 . GLU C 3 342 ? 172.451 181.574 186.925 1.00 132.54 ? 386 GLU C OE1 1 
ATOM   8731  O OE2 . GLU C 3 342 ? 173.972 180.813 185.536 1.00 132.54 ? 386 GLU C OE2 1 
ATOM   8732  N N   . ALA C 3 343 ? 173.191 184.855 182.106 1.00 160.52 ? 387 ALA C N   1 
ATOM   8733  C CA  . ALA C 3 343 ? 173.658 184.711 180.738 1.00 160.52 ? 387 ALA C CA  1 
ATOM   8734  C C   . ALA C 3 343 ? 174.442 183.417 180.563 1.00 160.52 ? 387 ALA C C   1 
ATOM   8735  O O   . ALA C 3 343 ? 174.958 182.852 181.533 1.00 160.52 ? 387 ALA C O   1 
ATOM   8736  C CB  . ALA C 3 343 ? 174.527 185.908 180.360 1.00 160.52 ? 387 ALA C CB  1 
ATOM   8737  N N   . PRO C 3 344 ? 174.549 182.913 179.323 1.00 192.26 ? 388 PRO C N   1 
ATOM   8738  C CA  . PRO C 3 344 ? 175.353 181.705 179.083 1.00 192.26 ? 388 PRO C CA  1 
ATOM   8739  C C   . PRO C 3 344 ? 176.838 181.923 179.329 1.00 192.26 ? 388 PRO C C   1 
ATOM   8740  O O   . PRO C 3 344 ? 177.264 183.027 179.682 1.00 192.26 ? 388 PRO C O   1 
ATOM   8741  C CB  . PRO C 3 344 ? 175.074 181.386 177.609 1.00 192.26 ? 388 PRO C CB  1 
ATOM   8742  C CG  . PRO C 3 344 ? 173.770 182.047 177.313 1.00 192.26 ? 388 PRO C CG  1 
ATOM   8743  C CD  . PRO C 3 344 ? 173.766 183.300 178.136 1.00 192.26 ? 388 PRO C CD  1 
ATOM   8744  N N   . THR C 3 345 ? 177.636 180.871 179.129 1.00 222.37 ? 389 THR C N   1 
ATOM   8745  C CA  . THR C 3 345 ? 179.047 180.914 179.501 1.00 222.37 ? 389 THR C CA  1 
ATOM   8746  C C   . THR C 3 345 ? 179.840 181.919 178.672 1.00 222.37 ? 389 THR C C   1 
ATOM   8747  O O   . THR C 3 345 ? 180.831 182.472 179.163 1.00 222.37 ? 389 THR C O   1 
ATOM   8748  C CB  . THR C 3 345 ? 179.667 179.523 179.365 1.00 222.37 ? 389 THR C CB  1 
ATOM   8749  O OG1 . THR C 3 345 ? 179.898 179.234 177.980 1.00 222.37 ? 389 THR C OG1 1 
ATOM   8750  C CG2 . THR C 3 345 ? 178.739 178.468 179.949 1.00 222.37 ? 389 THR C CG2 1 
ATOM   8751  N N   . ASN C 3 346 ? 179.436 182.163 177.422 1.00 221.64 ? 390 ASN C N   1 
ATOM   8752  C CA  . ASN C 3 346 ? 180.199 183.069 176.567 1.00 221.64 ? 390 ASN C CA  1 
ATOM   8753  C C   . ASN C 3 346 ? 180.179 184.493 177.108 1.00 221.64 ? 390 ASN C C   1 
ATOM   8754  O O   . ASN C 3 346 ? 181.187 185.207 177.039 1.00 221.64 ? 390 ASN C O   1 
ATOM   8755  C CB  . ASN C 3 346 ? 179.653 183.028 175.140 1.00 221.64 ? 390 ASN C CB  1 
ATOM   8756  C CG  . ASN C 3 346 ? 179.847 181.678 174.480 1.00 221.64 ? 390 ASN C CG  1 
ATOM   8757  O OD1 . ASN C 3 346 ? 179.010 180.785 174.611 1.00 221.64 ? 390 ASN C OD1 1 
ATOM   8758  N ND2 . ASN C 3 346 ? 180.953 181.523 173.762 1.00 221.64 ? 390 ASN C ND2 1 
ATOM   8759  N N   . GLU C 3 347 ? 179.042 184.921 177.654 1.00 184.80 ? 391 GLU C N   1 
ATOM   8760  C CA  . GLU C 3 347 ? 178.907 186.239 178.263 1.00 184.80 ? 391 GLU C CA  1 
ATOM   8761  C C   . GLU C 3 347 ? 178.511 186.093 179.729 1.00 184.80 ? 391 GLU C C   1 
ATOM   8762  O O   . GLU C 3 347 ? 177.615 186.793 180.213 1.00 184.80 ? 391 GLU C O   1 
ATOM   8763  C CB  . GLU C 3 347 ? 177.903 187.092 177.477 1.00 184.80 ? 391 GLU C CB  1 
ATOM   8764  C CG  . GLU C 3 347 ? 176.478 186.550 177.429 1.00 184.80 ? 391 GLU C CG  1 
ATOM   8765  C CD  . GLU C 3 347 ? 176.253 185.590 176.273 1.00 184.80 ? 391 GLU C CD  1 
ATOM   8766  O OE1 . GLU C 3 347 ? 177.248 185.077 175.721 1.00 184.80 ? 391 GLU C OE1 1 
ATOM   8767  O OE2 . GLU C 3 347 ? 175.079 185.348 175.919 1.00 184.80 ? 391 GLU C OE2 1 
ATOM   8768  N N   . SER C 3 348 ? 179.217 185.200 180.434 1.00 126.02 ? 392 SER C N   1 
ATOM   8769  C CA  . SER C 3 348 ? 178.833 184.720 181.762 1.00 126.02 ? 392 SER C CA  1 
ATOM   8770  C C   . SER C 3 348 ? 178.227 185.791 182.664 1.00 126.02 ? 392 SER C C   1 
ATOM   8771  O O   . SER C 3 348 ? 177.206 185.558 183.319 1.00 126.02 ? 392 SER C O   1 
ATOM   8772  C CB  . SER C 3 348 ? 180.052 184.090 182.441 1.00 126.02 ? 392 SER C CB  1 
ATOM   8773  O OG  . SER C 3 348 ? 179.751 183.703 183.771 1.00 126.02 ? 392 SER C OG  1 
ATOM   8774  N N   . TYR C 3 349 ? 178.837 186.973 182.711 1.00 68.37  ? 393 TYR C N   1 
ATOM   8775  C CA  . TYR C 3 349 ? 178.330 188.025 183.581 1.00 68.37  ? 393 TYR C CA  1 
ATOM   8776  C C   . TYR C 3 349 ? 178.571 189.386 182.948 1.00 68.37  ? 393 TYR C C   1 
ATOM   8777  O O   . TYR C 3 349 ? 179.684 189.683 182.505 1.00 68.37  ? 393 TYR C O   1 
ATOM   8778  C CB  . TYR C 3 349 ? 178.985 187.955 184.964 1.00 68.37  ? 393 TYR C CB  1 
ATOM   8779  C CG  . TYR C 3 349 ? 178.436 186.845 185.829 1.00 68.37  ? 393 TYR C CG  1 
ATOM   8780  C CD1 . TYR C 3 349 ? 177.156 186.923 186.360 1.00 68.37  ? 393 TYR C CD1 1 
ATOM   8781  C CD2 . TYR C 3 349 ? 179.194 185.717 186.111 1.00 68.37  ? 393 TYR C CD2 1 
ATOM   8782  C CE1 . TYR C 3 349 ? 176.646 185.910 187.148 1.00 68.37  ? 393 TYR C CE1 1 
ATOM   8783  C CE2 . TYR C 3 349 ? 178.693 184.699 186.899 1.00 68.37  ? 393 TYR C CE2 1 
ATOM   8784  C CZ  . TYR C 3 349 ? 177.419 184.801 187.415 1.00 68.37  ? 393 TYR C CZ  1 
ATOM   8785  O OH  . TYR C 3 349 ? 176.914 183.790 188.201 1.00 68.37  ? 393 TYR C OH  1 
ATOM   8786  N N   . GLN C 3 350 ? 177.520 190.202 182.911 1.00 55.16  ? 394 GLN C N   1 
ATOM   8787  C CA  . GLN C 3 350 ? 177.599 191.572 182.427 1.00 55.16  ? 394 GLN C CA  1 
ATOM   8788  C C   . GLN C 3 350 ? 176.458 192.360 183.053 1.00 55.16  ? 394 GLN C C   1 
ATOM   8789  O O   . GLN C 3 350 ? 175.357 191.830 183.226 1.00 55.16  ? 394 GLN C O   1 
ATOM   8790  C CB  . GLN C 3 350 ? 177.528 191.637 180.896 1.00 55.16  ? 394 GLN C CB  1 
ATOM   8791  C CG  . GLN C 3 350 ? 176.340 190.905 180.291 1.00 55.16  ? 394 GLN C CG  1 
ATOM   8792  C CD  . GLN C 3 350 ? 175.135 191.804 180.100 1.00 55.16  ? 394 GLN C CD  1 
ATOM   8793  O OE1 . GLN C 3 350 ? 175.272 193.015 179.924 1.00 55.16  ? 394 GLN C OE1 1 
ATOM   8794  N NE2 . GLN C 3 350 ? 173.945 191.216 180.136 1.00 55.16  ? 394 GLN C NE2 1 
ATOM   8795  N N   . LEU C 3 351 ? 176.726 193.617 183.396 1.00 48.33  ? 395 LEU C N   1 
ATOM   8796  C CA  . LEU C 3 351 ? 175.743 194.451 184.072 1.00 48.33  ? 395 LEU C CA  1 
ATOM   8797  C C   . LEU C 3 351 ? 175.849 195.883 183.571 1.00 48.33  ? 395 LEU C C   1 
ATOM   8798  O O   . LEU C 3 351 ? 176.950 196.393 183.349 1.00 48.33  ? 395 LEU C O   1 
ATOM   8799  C CB  . LEU C 3 351 ? 175.933 194.408 185.594 1.00 48.33  ? 395 LEU C CB  1 
ATOM   8800  C CG  . LEU C 3 351 ? 174.793 194.972 186.443 1.00 48.33  ? 395 LEU C CG  1 
ATOM   8801  C CD1 . LEU C 3 351 ? 173.466 194.352 186.039 1.00 48.33  ? 395 LEU C CD1 1 
ATOM   8802  C CD2 . LEU C 3 351 ? 175.068 194.735 187.918 1.00 48.33  ? 395 LEU C CD2 1 
ATOM   8803  N N   . LEU C 3 352 ? 174.696 196.523 183.397 1.00 49.07  ? 396 LEU C N   1 
ATOM   8804  C CA  . LEU C 3 352 ? 174.617 197.893 182.912 1.00 49.07  ? 396 LEU C CA  1 
ATOM   8805  C C   . LEU C 3 352 ? 174.473 198.855 184.084 1.00 49.07  ? 396 LEU C C   1 
ATOM   8806  O O   . LEU C 3 352 ? 173.777 198.562 185.060 1.00 49.07  ? 396 LEU C O   1 
ATOM   8807  C CB  . LEU C 3 352 ? 173.439 198.067 181.950 1.00 49.07  ? 396 LEU C CB  1 
ATOM   8808  C CG  . LEU C 3 352 ? 173.555 197.427 180.564 1.00 49.07  ? 396 LEU C CG  1 
ATOM   8809  C CD1 . LEU C 3 352 ? 173.121 195.968 180.592 1.00 49.07  ? 396 LEU C CD1 1 
ATOM   8810  C CD2 . LEU C 3 352 ? 172.743 198.212 179.546 1.00 49.07  ? 396 LEU C CD2 1 
ATOM   8811  N N   . PHE C 3 353 ? 175.135 200.006 183.979 1.00 54.95  ? 397 PHE C N   1 
ATOM   8812  C CA  . PHE C 3 353 ? 175.086 201.032 185.014 1.00 54.95  ? 397 PHE C CA  1 
ATOM   8813  C C   . PHE C 3 353 ? 174.892 202.385 184.348 1.00 54.95  ? 397 PHE C C   1 
ATOM   8814  O O   . PHE C 3 353 ? 175.642 202.741 183.435 1.00 54.95  ? 397 PHE C O   1 
ATOM   8815  C CB  . PHE C 3 353 ? 176.360 201.026 185.864 1.00 54.95  ? 397 PHE C CB  1 
ATOM   8816  C CG  . PHE C 3 353 ? 176.341 202.016 186.994 1.00 54.95  ? 397 PHE C CG  1 
ATOM   8817  C CD1 . PHE C 3 353 ? 177.028 203.215 186.895 1.00 54.95  ? 397 PHE C CD1 1 
ATOM   8818  C CD2 . PHE C 3 353 ? 175.637 201.747 188.156 1.00 54.95  ? 397 PHE C CD2 1 
ATOM   8819  C CE1 . PHE C 3 353 ? 177.013 204.126 187.934 1.00 54.95  ? 397 PHE C CE1 1 
ATOM   8820  C CE2 . PHE C 3 353 ? 175.618 202.655 189.198 1.00 54.95  ? 397 PHE C CE2 1 
ATOM   8821  C CZ  . PHE C 3 353 ? 176.307 203.846 189.086 1.00 54.95  ? 397 PHE C CZ  1 
ATOM   8822  N N   . GLN C 3 354 ? 173.889 203.130 184.802 1.00 60.03  ? 398 GLN C N   1 
ATOM   8823  C CA  . GLN C 3 354 ? 173.606 204.438 184.227 1.00 60.03  ? 398 GLN C CA  1 
ATOM   8824  C C   . GLN C 3 354 ? 174.615 205.467 184.723 1.00 60.03  ? 398 GLN C C   1 
ATOM   8825  O O   . GLN C 3 354 ? 174.918 205.531 185.918 1.00 60.03  ? 398 GLN C O   1 
ATOM   8826  C CB  . GLN C 3 354 ? 172.185 204.875 184.580 1.00 60.03  ? 398 GLN C CB  1 
ATOM   8827  C CG  . GLN C 3 354 ? 171.832 206.273 184.103 1.00 60.03  ? 398 GLN C CG  1 
ATOM   8828  C CD  . GLN C 3 354 ? 171.881 206.402 182.593 1.00 60.03  ? 398 GLN C CD  1 
ATOM   8829  O OE1 . GLN C 3 354 ? 171.583 205.454 181.867 1.00 60.03  ? 398 GLN C OE1 1 
ATOM   8830  N NE2 . GLN C 3 354 ? 172.264 207.579 182.113 1.00 60.03  ? 398 GLN C NE2 1 
ATOM   8831  N N   . MET C 3 355 ? 175.138 206.270 183.800 1.00 59.31  ? 399 MET C N   1 
ATOM   8832  C CA  . MET C 3 355 ? 176.085 207.310 184.164 1.00 59.31  ? 399 MET C CA  1 
ATOM   8833  C C   . MET C 3 355 ? 175.378 208.458 184.878 1.00 59.31  ? 399 MET C C   1 
ATOM   8834  O O   . MET C 3 355 ? 174.167 208.659 184.750 1.00 59.31  ? 399 MET C O   1 
ATOM   8835  C CB  . MET C 3 355 ? 176.808 207.840 182.927 1.00 59.31  ? 399 MET C CB  1 
ATOM   8836  C CG  . MET C 3 355 ? 177.801 206.868 182.320 1.00 59.31  ? 399 MET C CG  1 
ATOM   8837  S SD  . MET C 3 355 ? 178.783 207.620 181.009 1.00 59.31  ? 399 MET C SD  1 
ATOM   8838  C CE  . MET C 3 355 ? 179.438 209.055 181.856 1.00 59.31  ? 399 MET C CE  1 
ATOM   8839  N N   . LEU C 3 356 ? 176.159 209.220 185.639 1.00 58.37  ? 400 LEU C N   1 
ATOM   8840  C CA  . LEU C 3 356 ? 175.652 210.378 186.352 1.00 58.37  ? 400 LEU C CA  1 
ATOM   8841  C C   . LEU C 3 356 ? 176.200 211.644 185.713 1.00 58.37  ? 400 LEU C C   1 
ATOM   8842  O O   . LEU C 3 356 ? 177.406 211.716 185.442 1.00 58.37  ? 400 LEU C O   1 
ATOM   8843  C CB  . LEU C 3 356 ? 176.048 210.310 187.835 1.00 58.37  ? 400 LEU C CB  1 
ATOM   8844  C CG  . LEU C 3 356 ? 175.377 211.259 188.832 1.00 58.37  ? 400 LEU C CG  1 
ATOM   8845  C CD1 . LEU C 3 356 ? 175.282 210.594 190.193 1.00 58.37  ? 400 LEU C CD1 1 
ATOM   8846  C CD2 . LEU C 3 356 ? 176.133 212.569 188.946 1.00 58.37  ? 400 LEU C CD2 1 
ATOM   8847  N N   . PRO C 3 357 ? 175.361 212.644 185.448 1.00 58.96  ? 401 PRO C N   1 
ATOM   8848  C CA  . PRO C 3 357 ? 175.833 213.829 184.722 1.00 58.96  ? 401 PRO C CA  1 
ATOM   8849  C C   . PRO C 3 357 ? 176.867 214.615 185.512 1.00 58.96  ? 401 PRO C C   1 
ATOM   8850  O O   . PRO C 3 357 ? 176.816 214.699 186.742 1.00 58.96  ? 401 PRO C O   1 
ATOM   8851  C CB  . PRO C 3 357 ? 174.555 214.651 184.512 1.00 58.96  ? 401 PRO C CB  1 
ATOM   8852  C CG  . PRO C 3 357 ? 173.620 214.181 185.578 1.00 58.96  ? 401 PRO C CG  1 
ATOM   8853  C CD  . PRO C 3 357 ? 173.928 212.727 185.775 1.00 58.96  ? 401 PRO C CD  1 
ATOM   8854  N N   . ASN C 3 358 ? 177.819 215.193 184.776 1.00 48.54  ? 402 ASN C N   1 
ATOM   8855  C CA  . ASN C 3 358 ? 178.917 215.971 185.352 1.00 48.54  ? 402 ASN C CA  1 
ATOM   8856  C C   . ASN C 3 358 ? 179.758 215.137 186.315 1.00 48.54  ? 402 ASN C C   1 
ATOM   8857  O O   . ASN C 3 358 ? 180.312 215.658 187.286 1.00 48.54  ? 402 ASN C O   1 
ATOM   8858  C CB  . ASN C 3 358 ? 178.404 217.237 186.045 1.00 48.54  ? 402 ASN C CB  1 
ATOM   8859  C CG  . ASN C 3 358 ? 177.576 218.109 185.123 1.00 48.54  ? 402 ASN C CG  1 
ATOM   8860  O OD1 . ASN C 3 358 ? 177.783 218.119 183.909 1.00 48.54  ? 402 ASN C OD1 1 
ATOM   8861  N ND2 . ASN C 3 358 ? 176.634 218.849 185.695 1.00 48.54  ? 402 ASN C ND2 1 
ATOM   8862  N N   . GLN C 3 359 ? 179.859 213.836 186.052 1.00 54.90  ? 403 GLN C N   1 
ATOM   8863  C CA  . GLN C 3 359 ? 180.687 212.930 186.839 1.00 54.90  ? 403 GLN C CA  1 
ATOM   8864  C C   . GLN C 3 359 ? 181.478 212.053 185.884 1.00 54.90  ? 403 GLN C C   1 
ATOM   8865  O O   . GLN C 3 359 ? 180.891 211.328 185.074 1.00 54.90  ? 403 GLN C O   1 
ATOM   8866  C CB  . GLN C 3 359 ? 179.838 212.072 187.781 1.00 54.90  ? 403 GLN C CB  1 
ATOM   8867  C CG  . GLN C 3 359 ? 180.645 211.066 188.587 1.00 54.90  ? 403 GLN C CG  1 
ATOM   8868  C CD  . GLN C 3 359 ? 179.799 210.295 189.581 1.00 54.90  ? 403 GLN C CD  1 
ATOM   8869  O OE1 . GLN C 3 359 ? 178.671 210.683 189.886 1.00 54.90  ? 403 GLN C OE1 1 
ATOM   8870  N NE2 . GLN C 3 359 ? 180.340 209.195 190.091 1.00 54.90  ? 403 GLN C NE2 1 
ATOM   8871  N N   . GLU C 3 360 ? 182.804 212.118 185.977 1.00 52.85  ? 404 GLU C N   1 
ATOM   8872  C CA  . GLU C 3 360 ? 183.682 211.375 185.087 1.00 52.85  ? 404 GLU C CA  1 
ATOM   8873  C C   . GLU C 3 360 ? 184.524 210.321 185.788 1.00 52.85  ? 404 GLU C C   1 
ATOM   8874  O O   . GLU C 3 360 ? 184.810 209.285 185.185 1.00 52.85  ? 404 GLU C O   1 
ATOM   8875  C CB  . GLU C 3 360 ? 184.615 212.338 184.336 1.00 52.85  ? 404 GLU C CB  1 
ATOM   8876  C CG  . GLU C 3 360 ? 183.895 213.236 183.344 1.00 52.85  ? 404 GLU C CG  1 
ATOM   8877  C CD  . GLU C 3 360 ? 184.748 214.401 182.887 1.00 52.85  ? 404 GLU C CD  1 
ATOM   8878  O OE1 . GLU C 3 360 ? 185.310 215.104 183.753 1.00 52.85  ? 404 GLU C OE1 1 
ATOM   8879  O OE2 . GLU C 3 360 ? 184.855 214.616 181.661 1.00 52.85  ? 404 GLU C OE2 1 
ATOM   8880  N N   . ILE C 3 361 ? 184.927 210.552 187.032 1.00 53.04  ? 405 ILE C N   1 
ATOM   8881  C CA  . ILE C 3 361 ? 185.708 209.580 187.788 1.00 53.04  ? 405 ILE C CA  1 
ATOM   8882  C C   . ILE C 3 361 ? 184.751 208.611 188.467 1.00 53.04  ? 405 ILE C C   1 
ATOM   8883  O O   . ILE C 3 361 ? 183.803 209.030 189.143 1.00 53.04  ? 405 ILE C O   1 
ATOM   8884  C CB  . ILE C 3 361 ? 186.612 210.278 188.816 1.00 53.04  ? 405 ILE C CB  1 
ATOM   8885  C CG1 . ILE C 3 361 ? 187.554 211.258 188.115 1.00 53.04  ? 405 ILE C CG1 1 
ATOM   8886  C CG2 . ILE C 3 361 ? 187.404 209.253 189.611 1.00 53.04  ? 405 ILE C CG2 1 
ATOM   8887  C CD1 . ILE C 3 361 ? 188.504 211.970 189.053 1.00 53.04  ? 405 ILE C CD1 1 
ATOM   8888  N N   . TYR C 3 362 ? 184.993 207.315 188.285 1.00 53.62  ? 406 TYR C N   1 
ATOM   8889  C CA  . TYR C 3 362 ? 184.128 206.273 188.820 1.00 53.62  ? 406 TYR C CA  1 
ATOM   8890  C C   . TYR C 3 362 ? 184.963 205.280 189.612 1.00 53.62  ? 406 TYR C C   1 
ATOM   8891  O O   . TYR C 3 362 ? 185.995 204.804 189.127 1.00 53.62  ? 406 TYR C O   1 
ATOM   8892  C CB  . TYR C 3 362 ? 183.369 205.558 187.698 1.00 53.62  ? 406 TYR C CB  1 
ATOM   8893  C CG  . TYR C 3 362 ? 182.239 206.372 187.107 1.00 53.62  ? 406 TYR C CG  1 
ATOM   8894  C CD1 . TYR C 3 362 ? 180.918 206.104 187.436 1.00 53.62  ? 406 TYR C CD1 1 
ATOM   8895  C CD2 . TYR C 3 362 ? 182.495 207.409 186.220 1.00 53.62  ? 406 TYR C CD2 1 
ATOM   8896  C CE1 . TYR C 3 362 ? 179.883 206.845 186.898 1.00 53.62  ? 406 TYR C CE1 1 
ATOM   8897  C CE2 . TYR C 3 362 ? 181.467 208.156 185.678 1.00 53.62  ? 406 TYR C CE2 1 
ATOM   8898  C CZ  . TYR C 3 362 ? 180.163 207.869 186.020 1.00 53.62  ? 406 TYR C CZ  1 
ATOM   8899  O OH  . TYR C 3 362 ? 179.136 208.610 185.481 1.00 53.62  ? 406 TYR C OH  1 
ATOM   8900  N N   . ASN C 3 363 ? 184.513 204.969 190.825 1.00 65.61  ? 407 ASN C N   1 
ATOM   8901  C CA  . ASN C 3 363 ? 185.176 204.029 191.726 1.00 65.61  ? 407 ASN C CA  1 
ATOM   8902  C C   . ASN C 3 363 ? 184.158 202.939 192.051 1.00 65.61  ? 407 ASN C C   1 
ATOM   8903  O O   . ASN C 3 363 ? 183.377 203.061 192.997 1.00 65.61  ? 407 ASN C O   1 
ATOM   8904  C CB  . ASN C 3 363 ? 185.691 204.753 192.981 1.00 65.61  ? 407 ASN C CB  1 
ATOM   8905  C CG  . ASN C 3 363 ? 186.067 203.803 194.107 1.00 65.61  ? 407 ASN C CG  1 
ATOM   8906  O OD1 . ASN C 3 363 ? 186.518 202.680 193.877 1.00 65.61  ? 407 ASN C OD1 1 
ATOM   8907  N ND2 . ASN C 3 363 ? 185.884 204.263 195.340 1.00 65.61  ? 407 ASN C ND2 1 
ATOM   8908  N N   . PHE C 3 364 ? 184.166 201.875 191.252 1.00 57.09  ? 408 PHE C N   1 
ATOM   8909  C CA  . PHE C 3 364 ? 183.187 200.804 191.373 1.00 57.09  ? 408 PHE C CA  1 
ATOM   8910  C C   . PHE C 3 364 ? 183.649 199.761 192.381 1.00 57.09  ? 408 PHE C C   1 
ATOM   8911  O O   . PHE C 3 364 ? 184.845 199.479 192.501 1.00 57.09  ? 408 PHE C O   1 
ATOM   8912  C CB  . PHE C 3 364 ? 182.945 200.142 190.017 1.00 57.09  ? 408 PHE C CB  1 
ATOM   8913  C CG  . PHE C 3 364 ? 182.131 200.976 189.071 1.00 57.09  ? 408 PHE C CG  1 
ATOM   8914  C CD1 . PHE C 3 364 ? 180.767 201.122 189.254 1.00 57.09  ? 408 PHE C CD1 1 
ATOM   8915  C CD2 . PHE C 3 364 ? 182.729 201.608 187.995 1.00 57.09  ? 408 PHE C CD2 1 
ATOM   8916  C CE1 . PHE C 3 364 ? 180.015 201.888 188.384 1.00 57.09  ? 408 PHE C CE1 1 
ATOM   8917  C CE2 . PHE C 3 364 ? 181.982 202.374 187.121 1.00 57.09  ? 408 PHE C CE2 1 
ATOM   8918  C CZ  . PHE C 3 364 ? 180.624 202.514 187.317 1.00 57.09  ? 408 PHE C CZ  1 
ATOM   8919  N N   . THR C 3 365 ? 182.688 199.189 193.105 1.00 39.36  ? 409 THR C N   1 
ATOM   8920  C CA  . THR C 3 365 ? 182.945 198.137 194.088 1.00 39.36  ? 409 THR C CA  1 
ATOM   8921  C C   . THR C 3 365 ? 181.878 197.061 193.912 1.00 39.36  ? 409 THR C C   1 
ATOM   8922  O O   . THR C 3 365 ? 180.734 197.238 194.340 1.00 39.36  ? 409 THR C O   1 
ATOM   8923  C CB  . THR C 3 365 ? 182.941 198.691 195.510 1.00 39.36  ? 409 THR C CB  1 
ATOM   8924  O OG1 . THR C 3 365 ? 181.734 199.432 195.732 1.00 39.36  ? 409 THR C OG1 1 
ATOM   8925  C CG2 . THR C 3 365 ? 184.139 199.600 195.740 1.00 39.36  ? 409 THR C CG2 1 
ATOM   8926  N N   . LEU C 3 366 ? 182.251 195.950 193.282 1.00 32.22  ? 410 LEU C N   1 
ATOM   8927  C CA  . LEU C 3 366 ? 181.339 194.834 193.072 1.00 32.22  ? 410 LEU C CA  1 
ATOM   8928  C C   . LEU C 3 366 ? 181.423 193.870 194.248 1.00 32.22  ? 410 LEU C C   1 
ATOM   8929  O O   . LEU C 3 366 ? 182.520 193.491 194.670 1.00 32.22  ? 410 LEU C O   1 
ATOM   8930  C CB  . LEU C 3 366 ? 181.665 194.105 191.768 1.00 32.22  ? 410 LEU C CB  1 
ATOM   8931  C CG  . LEU C 3 366 ? 180.885 192.815 191.509 1.00 32.22  ? 410 LEU C CG  1 
ATOM   8932  C CD1 . LEU C 3 366 ? 179.388 193.087 191.474 1.00 32.22  ? 410 LEU C CD1 1 
ATOM   8933  C CD2 . LEU C 3 366 ? 181.345 192.160 190.216 1.00 32.22  ? 410 LEU C CD2 1 
ATOM   8934  N N   . ASN C 3 367 ? 180.265 193.476 194.771 1.00 37.46  ? 411 ASN C N   1 
ATOM   8935  C CA  . ASN C 3 367 ? 180.180 192.582 195.917 1.00 37.46  ? 411 ASN C CA  1 
ATOM   8936  C C   . ASN C 3 367 ? 179.311 191.383 195.565 1.00 37.46  ? 411 ASN C C   1 
ATOM   8937  O O   . ASN C 3 367 ? 178.174 191.547 195.109 1.00 37.46  ? 411 ASN C O   1 
ATOM   8938  C CB  . ASN C 3 367 ? 179.608 193.306 197.139 1.00 37.46  ? 411 ASN C CB  1 
ATOM   8939  C CG  . ASN C 3 367 ? 180.393 194.551 197.497 1.00 37.46  ? 411 ASN C CG  1 
ATOM   8940  O OD1 . ASN C 3 367 ? 181.602 194.621 197.280 1.00 37.46  ? 411 ASN C OD1 1 
ATOM   8941  N ND2 . ASN C 3 367 ? 179.706 195.544 198.049 1.00 37.46  ? 411 ASN C ND2 1 
ATOM   8942  N N   . ALA C 3 368 ? 179.847 190.185 195.778 1.00 41.52  ? 412 ALA C N   1 
ATOM   8943  C CA  . ALA C 3 368 ? 179.116 188.944 195.585 1.00 41.52  ? 412 ALA C CA  1 
ATOM   8944  C C   . ALA C 3 368 ? 178.855 188.290 196.935 1.00 41.52  ? 412 ALA C C   1 
ATOM   8945  O O   . ALA C 3 368 ? 179.627 188.460 197.883 1.00 41.52  ? 412 ALA C O   1 
ATOM   8946  C CB  . ALA C 3 368 ? 179.886 187.981 194.678 1.00 41.52  ? 412 ALA C CB  1 
ATOM   8947  N N   . HIS C 3 369 ? 177.759 187.540 197.017 1.00 48.50  ? 413 HIS C N   1 
ATOM   8948  C CA  . HIS C 3 369 ? 177.364 186.928 198.277 1.00 48.50  ? 413 HIS C CA  1 
ATOM   8949  C C   . HIS C 3 369 ? 176.561 185.664 198.014 1.00 48.50  ? 413 HIS C C   1 
ATOM   8950  O O   . HIS C 3 369 ? 175.670 185.649 197.161 1.00 48.50  ? 413 HIS C O   1 
ATOM   8951  C CB  . HIS C 3 369 ? 176.545 187.900 199.134 1.00 48.50  ? 413 HIS C CB  1 
ATOM   8952  C CG  . HIS C 3 369 ? 176.070 187.312 200.426 1.00 48.50  ? 413 HIS C CG  1 
ATOM   8953  N ND1 . HIS C 3 369 ? 174.856 186.671 200.550 1.00 48.50  ? 413 HIS C ND1 1 
ATOM   8954  C CD2 . HIS C 3 369 ? 176.646 187.266 201.650 1.00 48.50  ? 413 HIS C CD2 1 
ATOM   8955  C CE1 . HIS C 3 369 ? 174.705 186.257 201.795 1.00 48.50  ? 413 HIS C CE1 1 
ATOM   8956  N NE2 . HIS C 3 369 ? 175.777 186.605 202.483 1.00 48.50  ? 413 HIS C NE2 1 
ATOM   8957  N N   . ASN C 3 370 ? 176.885 184.614 198.755 1.00 82.10  ? 414 ASN C N   1 
ATOM   8958  C CA  . ASN C 3 370 ? 176.160 183.352 198.761 1.00 82.10  ? 414 ASN C CA  1 
ATOM   8959  C C   . ASN C 3 370 ? 175.899 182.963 200.204 1.00 82.10  ? 414 ASN C C   1 
ATOM   8960  O O   . ASN C 3 370 ? 176.459 183.561 201.129 1.00 82.10  ? 414 ASN C O   1 
ATOM   8961  C CB  . ASN C 3 370 ? 176.960 182.257 198.032 1.00 82.10  ? 414 ASN C CB  1 
ATOM   8962  C CG  . ASN C 3 370 ? 178.361 182.082 198.585 1.00 82.10  ? 414 ASN C CG  1 
ATOM   8963  O OD1 . ASN C 3 370 ? 178.772 182.785 199.506 1.00 82.10  ? 414 ASN C OD1 1 
ATOM   8964  N ND2 . ASN C 3 370 ? 179.101 181.133 198.024 1.00 82.10  ? 414 ASN C ND2 1 
ATOM   8965  N N   . PRO C 3 371 ? 175.037 181.961 200.444 1.00 36.14  ? 415 PRO C N   1 
ATOM   8966  C CA  . PRO C 3 371 ? 174.784 181.532 201.829 1.00 36.14  ? 415 PRO C CA  1 
ATOM   8967  C C   . PRO C 3 371 ? 176.011 180.990 202.553 1.00 36.14  ? 415 PRO C C   1 
ATOM   8968  O O   . PRO C 3 371 ? 175.923 180.626 203.730 1.00 36.14  ? 415 PRO C O   1 
ATOM   8969  C CB  . PRO C 3 371 ? 173.717 180.444 201.663 1.00 36.14  ? 415 PRO C CB  1 
ATOM   8970  C CG  . PRO C 3 371 ? 173.006 180.814 200.416 1.00 36.14  ? 415 PRO C CG  1 
ATOM   8971  C CD  . PRO C 3 371 ? 174.057 181.382 199.507 1.00 36.14  ? 415 PRO C CD  1 
ATOM   8972  N N   . LEU C 3 372 ? 177.156 180.929 201.873 1.00 52.14  ? 416 LEU C N   1 
ATOM   8973  C CA  . LEU C 3 372 ? 178.389 180.445 202.481 1.00 52.14  ? 416 LEU C CA  1 
ATOM   8974  C C   . LEU C 3 372 ? 179.383 181.551 202.806 1.00 52.14  ? 416 LEU C C   1 
ATOM   8975  O O   . LEU C 3 372 ? 180.112 181.438 203.796 1.00 52.14  ? 416 LEU C O   1 
ATOM   8976  C CB  . LEU C 3 372 ? 179.066 179.421 201.564 1.00 52.14  ? 416 LEU C CB  1 
ATOM   8977  C CG  . LEU C 3 372 ? 178.417 178.037 201.502 1.00 52.14  ? 416 LEU C CG  1 
ATOM   8978  C CD1 . LEU C 3 372 ? 179.151 177.146 200.514 1.00 52.14  ? 416 LEU C CD1 1 
ATOM   8979  C CD2 . LEU C 3 372 ? 178.379 177.399 202.882 1.00 52.14  ? 416 LEU C CD2 1 
ATOM   8980  N N   . GLY C 3 373 ? 179.434 182.608 202.008 1.00 50.46  ? 417 GLY C N   1 
ATOM   8981  C CA  . GLY C 3 373 ? 180.387 183.667 202.256 1.00 50.46  ? 417 GLY C CA  1 
ATOM   8982  C C   . GLY C 3 373 ? 180.093 184.897 201.429 1.00 50.46  ? 417 GLY C C   1 
ATOM   8983  O O   . GLY C 3 373 ? 178.952 185.143 201.036 1.00 50.46  ? 417 GLY C O   1 
ATOM   8984  N N   . ARG C 3 374 ? 181.145 185.672 201.173 1.00 41.46  ? 418 ARG C N   1 
ATOM   8985  C CA  . ARG C 3 374 ? 181.019 186.898 200.398 1.00 41.46  ? 418 ARG C CA  1 
ATOM   8986  C C   . ARG C 3 374 ? 182.392 187.309 199.888 1.00 41.46  ? 418 ARG C C   1 
ATOM   8987  O O   . ARG C 3 374 ? 183.417 186.979 200.490 1.00 41.46  ? 418 ARG C O   1 
ATOM   8988  C CB  . ARG C 3 374 ? 180.398 188.028 201.228 1.00 41.46  ? 418 ARG C CB  1 
ATOM   8989  C CG  . ARG C 3 374 ? 181.201 188.405 202.462 1.00 41.46  ? 418 ARG C CG  1 
ATOM   8990  C CD  . ARG C 3 374 ? 180.527 189.525 203.235 1.00 41.46  ? 418 ARG C CD  1 
ATOM   8991  N NE  . ARG C 3 374 ? 180.310 190.707 202.406 1.00 41.46  ? 418 ARG C NE  1 
ATOM   8992  C CZ  . ARG C 3 374 ? 181.201 191.679 202.243 1.00 41.46  ? 418 ARG C CZ  1 
ATOM   8993  N NH1 . ARG C 3 374 ? 180.918 192.717 201.469 1.00 41.46  ? 418 ARG C NH1 1 
ATOM   8994  N NH2 . ARG C 3 374 ? 182.376 191.613 202.853 1.00 41.46  ? 418 ARG C NH2 1 
ATOM   8995  N N   . SER C 3 375 ? 182.397 188.035 198.771 1.00 34.39  ? 419 SER C N   1 
ATOM   8996  C CA  . SER C 3 375 ? 183.624 188.529 198.163 1.00 34.39  ? 419 SER C CA  1 
ATOM   8997  C C   . SER C 3 375 ? 183.383 189.934 197.630 1.00 34.39  ? 419 SER C C   1 
ATOM   8998  O O   . SER C 3 375 ? 182.242 190.390 197.509 1.00 34.39  ? 419 SER C O   1 
ATOM   8999  C CB  . SER C 3 375 ? 184.111 187.602 197.042 1.00 34.39  ? 419 SER C CB  1 
ATOM   9000  O OG  . SER C 3 375 ? 185.297 188.100 196.449 1.00 34.39  ? 419 SER C OG  1 
ATOM   9001  N N   . GLN C 3 376 ? 184.475 190.624 197.305 1.00 41.64  ? 420 GLN C N   1 
ATOM   9002  C CA  . GLN C 3 376 ? 184.394 191.993 196.819 1.00 41.64  ? 420 GLN C CA  1 
ATOM   9003  C C   . GLN C 3 376 ? 185.578 192.275 195.905 1.00 41.64  ? 420 GLN C C   1 
ATOM   9004  O O   . GLN C 3 376 ? 186.551 191.519 195.859 1.00 41.64  ? 420 GLN C O   1 
ATOM   9005  C CB  . GLN C 3 376 ? 184.357 192.996 197.977 1.00 41.64  ? 420 GLN C CB  1 
ATOM   9006  C CG  . GLN C 3 376 ? 185.672 193.122 198.725 1.00 41.64  ? 420 GLN C CG  1 
ATOM   9007  C CD  . GLN C 3 376 ? 185.648 194.227 199.760 1.00 41.64  ? 420 GLN C CD  1 
ATOM   9008  O OE1 . GLN C 3 376 ? 184.602 194.816 200.031 1.00 41.64  ? 420 GLN C OE1 1 
ATOM   9009  N NE2 . GLN C 3 376 ? 186.805 194.516 200.345 1.00 41.64  ? 420 GLN C NE2 1 
ATOM   9010  N N   . SER C 3 377 ? 185.481 193.386 195.175 1.00 33.42  ? 421 SER C N   1 
ATOM   9011  C CA  . SER C 3 377 ? 186.539 193.809 194.265 1.00 33.42  ? 421 SER C CA  1 
ATOM   9012  C C   . SER C 3 377 ? 186.371 195.293 193.979 1.00 33.42  ? 421 SER C C   1 
ATOM   9013  O O   . SER C 3 377 ? 185.258 195.749 193.703 1.00 33.42  ? 421 SER C O   1 
ATOM   9014  C CB  . SER C 3 377 ? 186.503 193.004 192.961 1.00 33.42  ? 421 SER C CB  1 
ATOM   9015  O OG  . SER C 3 377 ? 187.171 193.694 191.919 1.00 33.42  ? 421 SER C OG  1 
ATOM   9016  N N   . THR C 3 378 ? 187.473 196.038 194.043 1.00 44.73  ? 422 THR C N   1 
ATOM   9017  C CA  . THR C 3 378 ? 187.466 197.477 193.825 1.00 44.73  ? 422 THR C CA  1 
ATOM   9018  C C   . THR C 3 378 ? 188.366 197.831 192.648 1.00 44.73  ? 422 THR C C   1 
ATOM   9019  O O   . THR C 3 378 ? 189.381 197.172 192.402 1.00 44.73  ? 422 THR C O   1 
ATOM   9020  C CB  . THR C 3 378 ? 187.938 198.238 195.072 1.00 44.73  ? 422 THR C CB  1 
ATOM   9021  O OG1 . THR C 3 378 ? 189.352 198.069 195.229 1.00 44.73  ? 422 THR C OG1 1 
ATOM   9022  C CG2 . THR C 3 378 ? 187.233 197.717 196.314 1.00 44.73  ? 422 THR C CG2 1 
ATOM   9023  N N   . ILE C 3 379 ? 187.985 198.884 191.925 1.00 57.21  ? 423 ILE C N   1 
ATOM   9024  C CA  . ILE C 3 379 ? 188.755 199.353 190.779 1.00 57.21  ? 423 ILE C CA  1 
ATOM   9025  C C   . ILE C 3 379 ? 188.350 200.790 190.493 1.00 57.21  ? 423 ILE C C   1 
ATOM   9026  O O   . ILE C 3 379 ? 187.193 201.174 190.683 1.00 57.21  ? 423 ILE C O   1 
ATOM   9027  C CB  . ILE C 3 379 ? 188.546 198.436 189.545 1.00 57.21  ? 423 ILE C CB  1 
ATOM   9028  C CG1 . ILE C 3 379 ? 189.479 198.843 188.403 1.00 57.21  ? 423 ILE C CG1 1 
ATOM   9029  C CG2 . ILE C 3 379 ? 187.092 198.456 189.093 1.00 57.21  ? 423 ILE C CG2 1 
ATOM   9030  C CD1 . ILE C 3 379 ? 189.344 197.985 187.166 1.00 57.21  ? 423 ILE C CD1 1 
ATOM   9031  N N   . LEU C 3 380 ? 189.315 201.591 190.049 1.00 55.06  ? 424 LEU C N   1 
ATOM   9032  C CA  . LEU C 3 380 ? 189.088 202.979 189.666 1.00 55.06  ? 424 LEU C CA  1 
ATOM   9033  C C   . LEU C 3 380 ? 189.161 203.079 188.148 1.00 55.06  ? 424 LEU C C   1 
ATOM   9034  O O   . LEU C 3 380 ? 190.174 202.704 187.547 1.00 55.06  ? 424 LEU C O   1 
ATOM   9035  C CB  . LEU C 3 380 ? 190.116 203.903 190.320 1.00 55.06  ? 424 LEU C CB  1 
ATOM   9036  C CG  . LEU C 3 380 ? 189.927 205.404 190.096 1.00 55.06  ? 424 LEU C CG  1 
ATOM   9037  C CD1 . LEU C 3 380 ? 188.637 205.884 190.742 1.00 55.06  ? 424 LEU C CD1 1 
ATOM   9038  C CD2 . LEU C 3 380 ? 191.120 206.180 190.630 1.00 55.06  ? 424 LEU C CD2 1 
ATOM   9039  N N   . VAL C 3 381 ? 188.094 203.583 187.533 1.00 54.86  ? 425 VAL C N   1 
ATOM   9040  C CA  . VAL C 3 381 ? 187.978 203.645 186.081 1.00 54.86  ? 425 VAL C CA  1 
ATOM   9041  C C   . VAL C 3 381 ? 187.640 205.071 185.668 1.00 54.86  ? 425 VAL C C   1 
ATOM   9042  O O   . VAL C 3 381 ? 186.867 205.760 186.342 1.00 54.86  ? 425 VAL C O   1 
ATOM   9043  C CB  . VAL C 3 381 ? 186.918 202.650 185.557 1.00 54.86  ? 425 VAL C CB  1 
ATOM   9044  C CG1 . VAL C 3 381 ? 185.565 202.909 186.205 1.00 54.86  ? 425 VAL C CG1 1 
ATOM   9045  C CG2 . VAL C 3 381 ? 186.815 202.711 184.038 1.00 54.86  ? 425 VAL C CG2 1 
ATOM   9046  N N   . ASN C 3 382 ? 188.239 205.518 184.565 1.00 54.11  ? 426 ASN C N   1 
ATOM   9047  C CA  . ASN C 3 382 ? 187.955 206.820 183.972 1.00 54.11  ? 426 ASN C CA  1 
ATOM   9048  C C   . ASN C 3 382 ? 187.020 206.600 182.788 1.00 54.11  ? 426 ASN C C   1 
ATOM   9049  O O   . ASN C 3 382 ? 187.410 205.993 181.785 1.00 54.11  ? 426 ASN C O   1 
ATOM   9050  C CB  . ASN C 3 382 ? 189.248 207.510 183.540 1.00 54.11  ? 426 ASN C CB  1 
ATOM   9051  C CG  . ASN C 3 382 ? 189.068 208.996 183.296 1.00 54.11  ? 426 ASN C CG  1 
ATOM   9052  O OD1 . ASN C 3 382 ? 187.959 209.524 183.380 1.00 54.11  ? 426 ASN C OD1 1 
ATOM   9053  N ND2 . ASN C 3 382 ? 190.167 209.679 182.994 1.00 54.11  ? 426 ASN C ND2 1 
ATOM   9054  N N   . ILE C 3 383 ? 185.783 207.091 182.907 1.00 54.18  ? 427 ILE C N   1 
ATOM   9055  C CA  . ILE C 3 383 ? 184.777 206.835 181.882 1.00 54.18  ? 427 ILE C CA  1 
ATOM   9056  C C   . ILE C 3 383 ? 185.109 207.525 180.565 1.00 54.18  ? 427 ILE C C   1 
ATOM   9057  O O   . ILE C 3 383 ? 184.607 207.116 179.512 1.00 54.18  ? 427 ILE C O   1 
ATOM   9058  C CB  . ILE C 3 383 ? 183.383 207.258 182.384 1.00 54.18  ? 427 ILE C CB  1 
ATOM   9059  C CG1 . ILE C 3 383 ? 182.287 206.557 181.578 1.00 54.18  ? 427 ILE C CG1 1 
ATOM   9060  C CG2 . ILE C 3 383 ? 183.218 208.769 182.315 1.00 54.18  ? 427 ILE C CG2 1 
ATOM   9061  C CD1 . ILE C 3 383 ? 182.380 205.048 181.608 1.00 54.18  ? 427 ILE C CD1 1 
ATOM   9062  N N   . THR C 3 384 ? 185.950 208.560 180.590 1.00 56.81  ? 428 THR C N   1 
ATOM   9063  C CA  . THR C 3 384 ? 186.305 209.265 179.365 1.00 56.81  ? 428 THR C CA  1 
ATOM   9064  C C   . THR C 3 384 ? 187.438 208.591 178.603 1.00 56.81  ? 428 THR C C   1 
ATOM   9065  O O   . THR C 3 384 ? 187.628 208.884 177.417 1.00 56.81  ? 428 THR C O   1 
ATOM   9066  C CB  . THR C 3 384 ? 186.690 210.710 179.684 1.00 56.81  ? 428 THR C CB  1 
ATOM   9067  O OG1 . THR C 3 384 ? 187.493 210.737 180.870 1.00 56.81  ? 428 THR C OG1 1 
ATOM   9068  C CG2 . THR C 3 384 ? 185.445 211.557 179.899 1.00 56.81  ? 428 THR C CG2 1 
ATOM   9069  N N   . GLU C 3 385 ? 188.190 207.702 179.247 1.00 54.95  ? 429 GLU C N   1 
ATOM   9070  C CA  . GLU C 3 385 ? 189.284 206.991 178.603 1.00 54.95  ? 429 GLU C CA  1 
ATOM   9071  C C   . GLU C 3 385 ? 188.935 205.549 178.260 1.00 54.95  ? 429 GLU C C   1 
ATOM   9072  O O   . GLU C 3 385 ? 189.782 204.835 177.714 1.00 54.95  ? 429 GLU C O   1 
ATOM   9073  C CB  . GLU C 3 385 ? 190.530 207.019 179.494 1.00 54.95  ? 429 GLU C CB  1 
ATOM   9074  C CG  . GLU C 3 385 ? 191.207 208.377 179.575 1.00 54.95  ? 429 GLU C CG  1 
ATOM   9075  C CD  . GLU C 3 385 ? 192.439 208.360 180.459 1.00 54.95  ? 429 GLU C CD  1 
ATOM   9076  O OE1 . GLU C 3 385 ? 192.387 208.938 181.565 1.00 54.95  ? 429 GLU C OE1 1 
ATOM   9077  O OE2 . GLU C 3 385 ? 193.459 207.769 180.048 1.00 54.95  ? 429 GLU C OE2 1 
ATOM   9078  N N   . LYS C 3 386 ? 187.718 205.106 178.564 1.00 51.13  ? 430 LYS C N   1 
ATOM   9079  C CA  . LYS C 3 386 ? 187.277 203.738 178.311 1.00 51.13  ? 430 LYS C CA  1 
ATOM   9080  C C   . LYS C 3 386 ? 185.994 203.740 177.492 1.00 51.13  ? 430 LYS C C   1 
ATOM   9081  O O   . LYS C 3 386 ? 185.032 203.028 177.787 1.00 51.13  ? 430 LYS C O   1 
ATOM   9082  C CB  . LYS C 3 386 ? 187.084 202.976 179.618 1.00 51.13  ? 430 LYS C CB  1 
ATOM   9083  C CG  . LYS C 3 386 ? 188.320 202.934 180.501 1.00 51.13  ? 430 LYS C CG  1 
ATOM   9084  C CD  . LYS C 3 386 ? 189.493 202.293 179.778 1.00 51.13  ? 430 LYS C CD  1 
ATOM   9085  C CE  . LYS C 3 386 ? 190.747 202.319 180.634 1.00 51.13  ? 430 LYS C CE  1 
ATOM   9086  N NZ  . LYS C 3 386 ? 191.149 203.710 180.981 1.00 51.13  ? 430 LYS C NZ  1 
ATOM   9087  N N   . VAL C 3 387 ? 185.967 204.555 176.444 1.00 45.25  ? 431 VAL C N   1 
ATOM   9088  C CA  . VAL C 3 387 ? 184.820 204.653 175.548 1.00 45.25  ? 431 VAL C CA  1 
ATOM   9089  C C   . VAL C 3 387 ? 185.069 203.768 174.335 1.00 45.25  ? 431 VAL C C   1 
ATOM   9090  O O   . VAL C 3 387 ? 186.177 203.740 173.784 1.00 45.25  ? 431 VAL C O   1 
ATOM   9091  C CB  . VAL C 3 387 ? 184.557 206.116 175.138 1.00 45.25  ? 431 VAL C CB  1 
ATOM   9092  C CG1 . VAL C 3 387 ? 185.799 206.737 174.512 1.00 45.25  ? 431 VAL C CG1 1 
ATOM   9093  C CG2 . VAL C 3 387 ? 183.370 206.203 174.189 1.00 45.25  ? 431 VAL C CG2 1 
ATOM   9094  N N   . TYR C 3 388 ? 184.040 203.027 173.926 1.00 41.76  ? 432 TYR C N   1 
ATOM   9095  C CA  . TYR C 3 388 ? 184.146 202.142 172.777 1.00 41.76  ? 432 TYR C CA  1 
ATOM   9096  C C   . TYR C 3 388 ? 183.520 202.818 171.569 1.00 41.76  ? 432 TYR C C   1 
ATOM   9097  O O   . TYR C 3 388 ? 182.298 203.031 171.557 1.00 41.76  ? 432 TYR C O   1 
ATOM   9098  C CB  . TYR C 3 388 ? 183.460 200.808 173.058 1.00 41.76  ? 432 TYR C CB  1 
ATOM   9099  C CG  . TYR C 3 388 ? 183.760 199.738 172.033 1.00 41.76  ? 432 TYR C CG  1 
ATOM   9100  C CD1 . TYR C 3 388 ? 182.881 199.482 170.989 1.00 41.76  ? 432 TYR C CD1 1 
ATOM   9101  C CD2 . TYR C 3 388 ? 184.923 198.983 172.110 1.00 41.76  ? 432 TYR C CD2 1 
ATOM   9102  C CE1 . TYR C 3 388 ? 183.151 198.505 170.051 1.00 41.76  ? 432 TYR C CE1 1 
ATOM   9103  C CE2 . TYR C 3 388 ? 185.201 198.003 171.176 1.00 41.76  ? 432 TYR C CE2 1 
ATOM   9104  C CZ  . TYR C 3 388 ? 184.312 197.769 170.149 1.00 41.76  ? 432 TYR C CZ  1 
ATOM   9105  O OH  . TYR C 3 388 ? 184.585 196.795 169.217 1.00 41.76  ? 432 TYR C OH  1 
ATOM   9106  N N   . PRO C 3 389 ? 184.296 203.177 170.546 1.00 46.14  ? 433 PRO C N   1 
ATOM   9107  C CA  . PRO C 3 389 ? 183.715 203.828 169.360 1.00 46.14  ? 433 PRO C CA  1 
ATOM   9108  C C   . PRO C 3 389 ? 182.766 202.884 168.639 1.00 46.14  ? 433 PRO C C   1 
ATOM   9109  O O   . PRO C 3 389 ? 183.150 201.783 168.239 1.00 46.14  ? 433 PRO C O   1 
ATOM   9110  C CB  . PRO C 3 389 ? 184.942 204.165 168.501 1.00 46.14  ? 433 PRO C CB  1 
ATOM   9111  C CG  . PRO C 3 389 ? 186.107 204.111 169.444 1.00 46.14  ? 433 PRO C CG  1 
ATOM   9112  C CD  . PRO C 3 389 ? 185.760 203.064 170.453 1.00 46.14  ? 433 PRO C CD  1 
ATOM   9113  N N   . HIS C 3 390 ? 181.520 203.320 168.480 1.00 68.47  ? 434 HIS C N   1 
ATOM   9114  C CA  . HIS C 3 390 ? 180.519 202.501 167.814 1.00 68.47  ? 434 HIS C CA  1 
ATOM   9115  C C   . HIS C 3 390 ? 180.842 202.359 166.330 1.00 68.47  ? 434 HIS C C   1 
ATOM   9116  O O   . HIS C 3 390 ? 181.502 203.211 165.729 1.00 68.47  ? 434 HIS C O   1 
ATOM   9117  C CB  . HIS C 3 390 ? 179.128 203.108 167.993 1.00 68.47  ? 434 HIS C CB  1 
ATOM   9118  C CG  . HIS C 3 390 ? 178.011 202.148 167.730 1.00 68.47  ? 434 HIS C CG  1 
ATOM   9119  N ND1 . HIS C 3 390 ? 177.497 201.931 166.470 1.00 68.47  ? 434 HIS C ND1 1 
ATOM   9120  C CD2 . HIS C 3 390 ? 177.308 201.347 168.565 1.00 68.47  ? 434 HIS C CD2 1 
ATOM   9121  C CE1 . HIS C 3 390 ? 176.527 201.037 166.540 1.00 68.47  ? 434 HIS C CE1 1 
ATOM   9122  N NE2 . HIS C 3 390 ? 176.391 200.668 167.800 1.00 68.47  ? 434 HIS C NE2 1 
ATOM   9123  N N   . THR C 3 391 ? 180.373 201.268 165.744 1.00 67.40  ? 435 THR C N   1 
ATOM   9124  C CA  . THR C 3 391 ? 180.625 200.999 164.334 1.00 67.40  ? 435 THR C CA  1 
ATOM   9125  C C   . THR C 3 391 ? 179.879 202.004 163.467 1.00 67.40  ? 435 THR C C   1 
ATOM   9126  O O   . THR C 3 391 ? 178.651 202.115 163.583 1.00 67.40  ? 435 THR C O   1 
ATOM   9127  C CB  . THR C 3 391 ? 180.200 199.577 163.980 1.00 67.40  ? 435 THR C CB  1 
ATOM   9128  O OG1 . THR C 3 391 ? 180.938 198.642 164.778 1.00 67.40  ? 435 THR C OG1 1 
ATOM   9129  C CG2 . THR C 3 391 ? 180.460 199.294 162.508 1.00 67.40  ? 435 THR C CG2 1 
ATOM   9130  N N   . PRO C 3 392 ? 180.562 202.755 162.605 1.00 68.55  ? 436 PRO C N   1 
ATOM   9131  C CA  . PRO C 3 392 ? 179.857 203.717 161.749 1.00 68.55  ? 436 PRO C CA  1 
ATOM   9132  C C   . PRO C 3 392 ? 178.958 203.010 160.747 1.00 68.55  ? 436 PRO C C   1 
ATOM   9133  O O   . PRO C 3 392 ? 179.283 201.934 160.241 1.00 68.55  ? 436 PRO C O   1 
ATOM   9134  C CB  . PRO C 3 392 ? 180.994 204.471 161.046 1.00 68.55  ? 436 PRO C CB  1 
ATOM   9135  C CG  . PRO C 3 392 ? 182.222 204.186 161.860 1.00 68.55  ? 436 PRO C CG  1 
ATOM   9136  C CD  . PRO C 3 392 ? 182.021 202.819 162.427 1.00 68.55  ? 436 PRO C CD  1 
ATOM   9137  N N   . THR C 3 393 ? 177.815 203.631 160.464 1.00 75.85  ? 437 THR C N   1 
ATOM   9138  C CA  . THR C 3 393 ? 176.822 203.075 159.558 1.00 75.85  ? 437 THR C CA  1 
ATOM   9139  C C   . THR C 3 393 ? 176.416 204.127 158.535 1.00 75.85  ? 437 THR C C   1 
ATOM   9140  O O   . THR C 3 393 ? 176.777 205.303 158.639 1.00 75.85  ? 437 THR C O   1 
ATOM   9141  C CB  . THR C 3 393 ? 175.585 202.574 160.318 1.00 75.85  ? 437 THR C CB  1 
ATOM   9142  O OG1 . THR C 3 393 ? 175.066 203.628 161.138 1.00 75.85  ? 437 THR C OG1 1 
ATOM   9143  C CG2 . THR C 3 393 ? 175.941 201.382 161.195 1.00 75.85  ? 437 THR C CG2 1 
ATOM   9144  N N   . SER C 3 394 ? 175.651 203.680 157.536 1.00 83.81  ? 438 SER C N   1 
ATOM   9145  C CA  . SER C 3 394 ? 175.144 204.540 156.464 1.00 83.81  ? 438 SER C CA  1 
ATOM   9146  C C   . SER C 3 394 ? 176.286 205.248 155.736 1.00 83.81  ? 438 SER C C   1 
ATOM   9147  O O   . SER C 3 394 ? 176.267 206.464 155.531 1.00 83.81  ? 438 SER C O   1 
ATOM   9148  C CB  . SER C 3 394 ? 174.123 205.549 156.998 1.00 83.81  ? 438 SER C CB  1 
ATOM   9149  O OG  . SER C 3 394 ? 174.747 206.533 157.804 1.00 83.81  ? 438 SER C OG  1 
ATOM   9150  N N   . PHE C 3 395 ? 177.292 204.471 155.343 1.00 82.51  ? 439 PHE C N   1 
ATOM   9151  C CA  . PHE C 3 395 ? 178.434 205.011 154.617 1.00 82.51  ? 439 PHE C CA  1 
ATOM   9152  C C   . PHE C 3 395 ? 178.070 205.170 153.145 1.00 82.51  ? 439 PHE C C   1 
ATOM   9153  O O   . PHE C 3 395 ? 177.789 204.182 152.459 1.00 82.51  ? 439 PHE C O   1 
ATOM   9154  C CB  . PHE C 3 395 ? 179.650 204.103 154.780 1.00 82.51  ? 439 PHE C CB  1 
ATOM   9155  C CG  . PHE C 3 395 ? 180.894 204.634 154.127 1.00 82.51  ? 439 PHE C CG  1 
ATOM   9156  C CD1 . PHE C 3 395 ? 181.334 204.116 152.921 1.00 82.51  ? 439 PHE C CD1 1 
ATOM   9157  C CD2 . PHE C 3 395 ? 181.620 205.655 154.716 1.00 82.51  ? 439 PHE C CD2 1 
ATOM   9158  C CE1 . PHE C 3 395 ? 182.478 204.603 152.317 1.00 82.51  ? 439 PHE C CE1 1 
ATOM   9159  C CE2 . PHE C 3 395 ? 182.763 206.147 154.117 1.00 82.51  ? 439 PHE C CE2 1 
ATOM   9160  C CZ  . PHE C 3 395 ? 183.192 205.620 152.916 1.00 82.51  ? 439 PHE C CZ  1 
ATOM   9161  N N   . LYS C 3 396 ? 178.075 206.410 152.664 1.00 92.74  ? 440 LYS C N   1 
ATOM   9162  C CA  . LYS C 3 396 ? 177.722 206.720 151.287 1.00 92.74  ? 440 LYS C CA  1 
ATOM   9163  C C   . LYS C 3 396 ? 178.880 207.427 150.596 1.00 92.74  ? 440 LYS C C   1 
ATOM   9164  O O   . LYS C 3 396 ? 179.696 208.095 151.238 1.00 92.74  ? 440 LYS C O   1 
ATOM   9165  C CB  . LYS C 3 396 ? 176.463 207.592 151.218 1.00 92.74  ? 440 LYS C CB  1 
ATOM   9166  C CG  . LYS C 3 396 ? 175.217 206.923 151.773 1.00 92.74  ? 440 LYS C CG  1 
ATOM   9167  C CD  . LYS C 3 396 ? 173.997 207.816 151.622 1.00 92.74  ? 440 LYS C CD  1 
ATOM   9168  C CE  . LYS C 3 396 ? 172.744 207.130 152.142 1.00 92.74  ? 440 LYS C CE  1 
ATOM   9169  N NZ  . LYS C 3 396 ? 171.536 207.987 151.987 1.00 92.74  ? 440 LYS C NZ  1 
ATOM   9170  N N   . VAL C 3 397 ? 178.940 207.273 149.275 1.00 85.99  ? 441 VAL C N   1 
ATOM   9171  C CA  . VAL C 3 397 ? 179.978 207.871 148.446 1.00 85.99  ? 441 VAL C CA  1 
ATOM   9172  C C   . VAL C 3 397 ? 179.311 208.805 147.447 1.00 85.99  ? 441 VAL C C   1 
ATOM   9173  O O   . VAL C 3 397 ? 178.342 208.420 146.782 1.00 85.99  ? 441 VAL C O   1 
ATOM   9174  C CB  . VAL C 3 397 ? 180.813 206.800 147.721 1.00 85.99  ? 441 VAL C CB  1 
ATOM   9175  C CG1 . VAL C 3 397 ? 181.933 207.449 146.924 1.00 85.99  ? 441 VAL C CG1 1 
ATOM   9176  C CG2 . VAL C 3 397 ? 181.372 205.797 148.718 1.00 85.99  ? 441 VAL C CG2 1 
ATOM   9177  N N   . LYS C 3 398 ? 179.827 210.028 147.343 1.00 68.96  ? 442 LYS C N   1 
ATOM   9178  C CA  . LYS C 3 398 ? 179.292 211.034 146.437 1.00 68.96  ? 442 LYS C CA  1 
ATOM   9179  C C   . LYS C 3 398 ? 180.434 211.708 145.694 1.00 68.96  ? 442 LYS C C   1 
ATOM   9180  O O   . LYS C 3 398 ? 181.478 212.005 146.281 1.00 68.96  ? 442 LYS C O   1 
ATOM   9181  C CB  . LYS C 3 398 ? 178.467 212.082 147.193 1.00 68.96  ? 442 LYS C CB  1 
ATOM   9182  C CG  . LYS C 3 398 ? 177.209 211.532 147.843 1.00 68.96  ? 442 LYS C CG  1 
ATOM   9183  C CD  . LYS C 3 398 ? 176.691 212.470 148.919 1.00 68.96  ? 442 LYS C CD  1 
ATOM   9184  C CE  . LYS C 3 398 ? 177.729 212.672 150.010 1.00 68.96  ? 442 LYS C CE  1 
ATOM   9185  N NZ  . LYS C 3 398 ? 178.202 211.375 150.566 1.00 68.96  ? 442 LYS C NZ  1 
ATOM   9186  N N   . ASP C 3 399 ? 180.230 211.949 144.402 1.00 78.21  ? 443 ASP C N   1 
ATOM   9187  C CA  . ASP C 3 399 ? 181.254 212.572 143.581 1.00 78.21  ? 443 ASP C CA  1 
ATOM   9188  C C   . ASP C 3 399 ? 181.177 214.094 143.679 1.00 78.21  ? 443 ASP C C   1 
ATOM   9189  O O   . ASP C 3 399 ? 180.138 214.674 144.007 1.00 78.21  ? 443 ASP C O   1 
ATOM   9190  C CB  . ASP C 3 399 ? 181.116 212.134 142.123 1.00 78.21  ? 443 ASP C CB  1 
ATOM   9191  C CG  . ASP C 3 399 ? 181.365 210.651 141.935 1.00 78.21  ? 443 ASP C CG  1 
ATOM   9192  O OD1 . ASP C 3 399 ? 182.168 210.080 142.702 1.00 78.21  ? 443 ASP C OD1 1 
ATOM   9193  O OD2 . ASP C 3 399 ? 180.757 210.055 141.021 1.00 78.21  ? 443 ASP C OD2 1 
ATOM   9194  N N   . ILE C 3 400 ? 182.305 214.739 143.385 1.00 76.08  ? 444 ILE C N   1 
ATOM   9195  C CA  . ILE C 3 400 ? 182.393 216.195 143.397 1.00 76.08  ? 444 ILE C CA  1 
ATOM   9196  C C   . ILE C 3 400 ? 182.815 216.680 142.017 1.00 76.08  ? 444 ILE C C   1 
ATOM   9197  O O   . ILE C 3 400 ? 182.089 217.435 141.361 1.00 76.08  ? 444 ILE C O   1 
ATOM   9198  C CB  . ILE C 3 400 ? 183.373 216.689 144.477 1.00 76.08  ? 444 ILE C CB  1 
ATOM   9199  C CG1 . ILE C 3 400 ? 182.839 216.362 145.872 1.00 76.08  ? 444 ILE C CG1 1 
ATOM   9200  C CG2 . ILE C 3 400 ? 183.619 218.183 144.331 1.00 76.08  ? 444 ILE C CG2 1 
ATOM   9201  C CD1 . ILE C 3 400 ? 183.723 216.861 146.993 1.00 76.08  ? 444 ILE C CD1 1 
ATOM   9202  N N   . ASN C 3 401 ? 183.989 216.250 141.572 1.00 74.61  ? 445 ASN C N   1 
ATOM   9203  C CA  . ASN C 3 401 ? 184.512 216.626 140.264 1.00 74.61  ? 445 ASN C CA  1 
ATOM   9204  C C   . ASN C 3 401 ? 185.480 215.536 139.816 1.00 74.61  ? 445 ASN C C   1 
ATOM   9205  O O   . ASN C 3 401 ? 185.487 214.431 140.367 1.00 74.61  ? 445 ASN C O   1 
ATOM   9206  C CB  . ASN C 3 401 ? 185.148 218.026 140.315 1.00 74.61  ? 445 ASN C CB  1 
ATOM   9207  C CG  . ASN C 3 401 ? 186.254 218.126 141.340 1.00 74.61  ? 445 ASN C CG  1 
ATOM   9208  O OD1 . ASN C 3 401 ? 186.245 217.424 142.348 1.00 74.61  ? 445 ASN C OD1 1 
ATOM   9209  N ND2 . ASN C 3 401 ? 187.217 219.006 141.087 1.00 74.61  ? 445 ASN C ND2 1 
ATOM   9210  N N   . SER C 3 402 ? 186.296 215.846 138.805 1.00 102.54 ? 446 SER C N   1 
ATOM   9211  C CA  . SER C 3 402 ? 187.129 214.825 138.177 1.00 102.54 ? 446 SER C CA  1 
ATOM   9212  C C   . SER C 3 402 ? 188.149 214.242 139.148 1.00 102.54 ? 446 SER C C   1 
ATOM   9213  O O   . SER C 3 402 ? 188.376 213.027 139.162 1.00 102.54 ? 446 SER C O   1 
ATOM   9214  C CB  . SER C 3 402 ? 187.830 215.408 136.950 1.00 102.54 ? 446 SER C CB  1 
ATOM   9215  O OG  . SER C 3 402 ? 186.966 215.422 135.828 1.00 102.54 ? 446 SER C OG  1 
ATOM   9216  N N   . THR C 3 403 ? 188.772 215.084 139.969 1.00 94.75  ? 447 THR C N   1 
ATOM   9217  C CA  . THR C 3 403 ? 189.888 214.669 140.811 1.00 94.75  ? 447 THR C CA  1 
ATOM   9218  C C   . THR C 3 403 ? 189.556 214.787 142.295 1.00 94.75  ? 447 THR C C   1 
ATOM   9219  O O   . THR C 3 403 ? 190.400 215.171 143.107 1.00 94.75  ? 447 THR C O   1 
ATOM   9220  C CB  . THR C 3 403 ? 191.143 215.475 140.484 1.00 94.75  ? 447 THR C CB  1 
ATOM   9221  O OG1 . THR C 3 403 ? 190.863 216.875 140.619 1.00 94.75  ? 447 THR C OG1 1 
ATOM   9222  C CG2 . THR C 3 403 ? 191.605 215.190 139.063 1.00 94.75  ? 447 THR C CG2 1 
ATOM   9223  N N   . ALA C 3 404 ? 188.325 214.445 142.670 1.00 89.00  ? 448 ALA C N   1 
ATOM   9224  C CA  . ALA C 3 404 ? 187.933 214.449 144.074 1.00 89.00  ? 448 ALA C CA  1 
ATOM   9225  C C   . ALA C 3 404 ? 186.635 213.672 144.237 1.00 89.00  ? 448 ALA C C   1 
ATOM   9226  O O   . ALA C 3 404 ? 185.815 213.604 143.318 1.00 89.00  ? 448 ALA C O   1 
ATOM   9227  C CB  . ALA C 3 404 ? 187.767 215.872 144.619 1.00 89.00  ? 448 ALA C CB  1 
ATOM   9228  N N   . VAL C 3 405 ? 186.464 213.088 145.423 1.00 74.89  ? 449 VAL C N   1 
ATOM   9229  C CA  . VAL C 3 405 ? 185.255 212.357 145.778 1.00 74.89  ? 449 VAL C CA  1 
ATOM   9230  C C   . VAL C 3 405 ? 184.941 212.646 147.241 1.00 74.89  ? 449 VAL C C   1 
ATOM   9231  O O   . VAL C 3 405 ? 185.835 212.929 148.044 1.00 74.89  ? 449 VAL C O   1 
ATOM   9232  C CB  . VAL C 3 405 ? 185.406 210.837 145.522 1.00 74.89  ? 449 VAL C CB  1 
ATOM   9233  C CG1 . VAL C 3 405 ? 186.379 210.214 146.512 1.00 74.89  ? 449 VAL C CG1 1 
ATOM   9234  C CG2 . VAL C 3 405 ? 184.053 210.140 145.563 1.00 74.89  ? 449 VAL C CG2 1 
ATOM   9235  N N   . LYS C 3 406 ? 183.656 212.588 147.582 1.00 71.43  ? 450 LYS C N   1 
ATOM   9236  C CA  . LYS C 3 406 ? 183.179 212.924 148.915 1.00 71.43  ? 450 LYS C CA  1 
ATOM   9237  C C   . LYS C 3 406 ? 182.621 211.685 149.603 1.00 71.43  ? 450 LYS C C   1 
ATOM   9238  O O   . LYS C 3 406 ? 181.993 210.835 148.963 1.00 71.43  ? 450 LYS C O   1 
ATOM   9239  C CB  . LYS C 3 406 ? 182.104 214.012 148.849 1.00 71.43  ? 450 LYS C CB  1 
ATOM   9240  C CG  . LYS C 3 406 ? 181.857 214.729 150.165 1.00 71.43  ? 450 LYS C CG  1 
ATOM   9241  C CD  . LYS C 3 406 ? 180.926 215.915 149.975 1.00 71.43  ? 450 LYS C CD  1 
ATOM   9242  C CE  . LYS C 3 406 ? 180.857 216.773 151.227 1.00 71.43  ? 450 LYS C CE  1 
ATOM   9243  N NZ  . LYS C 3 406 ? 179.959 217.946 151.045 1.00 71.43  ? 450 LYS C NZ  1 
ATOM   9244  N N   . LEU C 3 407 ? 182.853 211.590 150.910 1.00 78.27  ? 451 LEU C N   1 
ATOM   9245  C CA  . LEU C 3 407 ? 182.362 210.491 151.725 1.00 78.27  ? 451 LEU C CA  1 
ATOM   9246  C C   . LEU C 3 407 ? 181.453 211.026 152.824 1.00 78.27  ? 451 LEU C C   1 
ATOM   9247  O O   . LEU C 3 407 ? 181.434 212.225 153.116 1.00 78.27  ? 451 LEU C O   1 
ATOM   9248  C CB  . LEU C 3 407 ? 183.519 209.696 152.345 1.00 78.27  ? 451 LEU C CB  1 
ATOM   9249  C CG  . LEU C 3 407 ? 184.517 209.081 151.363 1.00 78.27  ? 451 LEU C CG  1 
ATOM   9250  C CD1 . LEU C 3 407 ? 185.591 208.303 152.106 1.00 78.27  ? 451 LEU C CD1 1 
ATOM   9251  C CD2 . LEU C 3 407 ? 183.802 208.191 150.358 1.00 78.27  ? 451 LEU C CD2 1 
ATOM   9252  N N   . SER C 3 408 ? 180.696 210.117 153.435 1.00 81.04  ? 452 SER C N   1 
ATOM   9253  C CA  . SER C 3 408 ? 179.768 210.487 154.494 1.00 81.04  ? 452 SER C CA  1 
ATOM   9254  C C   . SER C 3 408 ? 179.418 209.250 155.307 1.00 81.04  ? 452 SER C C   1 
ATOM   9255  O O   . SER C 3 408 ? 179.251 208.163 154.749 1.00 81.04  ? 452 SER C O   1 
ATOM   9256  C CB  . SER C 3 408 ? 178.495 211.124 153.924 1.00 81.04  ? 452 SER C CB  1 
ATOM   9257  O OG  . SER C 3 408 ? 177.535 210.135 153.592 1.00 81.04  ? 452 SER C OG  1 
ATOM   9258  N N   . TRP C 3 409 ? 179.309 209.427 156.622 1.00 70.66  ? 453 TRP C N   1 
ATOM   9259  C CA  . TRP C 3 409 ? 178.930 208.341 157.516 1.00 70.66  ? 453 TRP C CA  1 
ATOM   9260  C C   . TRP C 3 409 ? 178.301 208.937 158.766 1.00 70.66  ? 453 TRP C C   1 
ATOM   9261  O O   . TRP C 3 409 ? 178.503 210.111 159.085 1.00 70.66  ? 453 TRP C O   1 
ATOM   9262  C CB  . TRP C 3 409 ? 180.130 207.459 157.877 1.00 70.66  ? 453 TRP C CB  1 
ATOM   9263  C CG  . TRP C 3 409 ? 181.203 208.175 158.637 1.00 70.66  ? 453 TRP C CG  1 
ATOM   9264  C CD1 . TRP C 3 409 ? 181.403 208.156 159.986 1.00 70.66  ? 453 TRP C CD1 1 
ATOM   9265  C CD2 . TRP C 3 409 ? 182.228 209.012 158.091 1.00 70.66  ? 453 TRP C CD2 1 
ATOM   9266  N NE1 . TRP C 3 409 ? 182.488 208.931 160.314 1.00 70.66  ? 453 TRP C NE1 1 
ATOM   9267  C CE2 . TRP C 3 409 ? 183.013 209.468 159.168 1.00 70.66  ? 453 TRP C CE2 1 
ATOM   9268  C CE3 . TRP C 3 409 ? 182.559 209.421 156.795 1.00 70.66  ? 453 TRP C CE3 1 
ATOM   9269  C CZ2 . TRP C 3 409 ? 184.106 210.313 158.991 1.00 70.66  ? 453 TRP C CZ2 1 
ATOM   9270  C CZ3 . TRP C 3 409 ? 183.645 210.259 156.621 1.00 70.66  ? 453 TRP C CZ3 1 
ATOM   9271  C CH2 . TRP C 3 409 ? 184.405 210.696 157.713 1.00 70.66  ? 453 TRP C CH2 1 
ATOM   9272  N N   . HIS C 3 410 ? 177.536 208.108 159.470 1.00 74.10  ? 454 HIS C N   1 
ATOM   9273  C CA  . HIS C 3 410 ? 176.803 208.526 160.656 1.00 74.10  ? 454 HIS C CA  1 
ATOM   9274  C C   . HIS C 3 410 ? 177.387 207.860 161.895 1.00 74.10  ? 454 HIS C C   1 
ATOM   9275  O O   . HIS C 3 410 ? 177.801 206.697 161.850 1.00 74.10  ? 454 HIS C O   1 
ATOM   9276  C CB  . HIS C 3 410 ? 175.317 208.179 160.528 1.00 74.10  ? 454 HIS C CB  1 
ATOM   9277  C CG  . HIS C 3 410 ? 174.460 208.776 161.601 1.00 74.10  ? 454 HIS C CG  1 
ATOM   9278  N ND1 . HIS C 3 410 ? 174.359 210.135 161.803 1.00 74.10  ? 454 HIS C ND1 1 
ATOM   9279  C CD2 . HIS C 3 410 ? 173.663 208.197 162.530 1.00 74.10  ? 454 HIS C CD2 1 
ATOM   9280  C CE1 . HIS C 3 410 ? 173.537 210.369 162.811 1.00 74.10  ? 454 HIS C CE1 1 
ATOM   9281  N NE2 . HIS C 3 410 ? 173.101 209.209 163.269 1.00 74.10  ? 454 HIS C NE2 1 
ATOM   9282  N N   . LEU C 3 411 ? 177.418 208.605 162.999 1.00 73.19  ? 455 LEU C N   1 
ATOM   9283  C CA  . LEU C 3 411 ? 177.943 208.099 164.261 1.00 73.19  ? 455 LEU C CA  1 
ATOM   9284  C C   . LEU C 3 411 ? 177.044 208.524 165.415 1.00 73.19  ? 455 LEU C C   1 
ATOM   9285  O O   . LEU C 3 411 ? 177.029 209.704 165.790 1.00 73.19  ? 455 LEU C O   1 
ATOM   9286  C CB  . LEU C 3 411 ? 179.372 208.595 164.490 1.00 73.19  ? 455 LEU C CB  1 
ATOM   9287  C CG  . LEU C 3 411 ? 180.489 207.792 163.822 1.00 73.19  ? 455 LEU C CG  1 
ATOM   9288  C CD1 . LEU C 3 411 ? 181.840 208.449 164.058 1.00 73.19  ? 455 LEU C CD1 1 
ATOM   9289  C CD2 . LEU C 3 411 ? 180.492 206.360 164.332 1.00 73.19  ? 455 LEU C CD2 1 
ATOM   9290  N N   . PRO C 3 412 ? 176.284 207.602 166.001 1.00 77.42  ? 456 PRO C N   1 
ATOM   9291  C CA  . PRO C 3 412 ? 175.418 207.966 167.128 1.00 77.42  ? 456 PRO C CA  1 
ATOM   9292  C C   . PRO C 3 412 ? 176.207 208.118 168.419 1.00 77.42  ? 456 PRO C C   1 
ATOM   9293  O O   . PRO C 3 412 ? 177.092 207.317 168.732 1.00 77.42  ? 456 PRO C O   1 
ATOM   9294  C CB  . PRO C 3 412 ? 174.439 206.789 167.212 1.00 77.42  ? 456 PRO C CB  1 
ATOM   9295  C CG  . PRO C 3 412 ? 175.211 205.633 166.671 1.00 77.42  ? 456 PRO C CG  1 
ATOM   9296  C CD  . PRO C 3 412 ? 176.130 206.189 165.612 1.00 77.42  ? 456 PRO C CD  1 
ATOM   9297  N N   . GLY C 3 413 ? 175.878 209.157 169.166 1.00 69.27  ? 457 GLY C N   1 
ATOM   9298  C CA  . GLY C 3 413 ? 176.514 209.438 170.440 1.00 69.27  ? 457 GLY C CA  1 
ATOM   9299  C C   . GLY C 3 413 ? 176.756 210.924 170.617 1.00 69.27  ? 457 GLY C C   1 
ATOM   9300  O O   . GLY C 3 413 ? 176.772 211.703 169.663 1.00 69.27  ? 457 GLY C O   1 
ATOM   9301  N N   . ASN C 3 414 ? 176.950 211.326 171.871 1.00 63.47  ? 458 ASN C N   1 
ATOM   9302  C CA  . ASN C 3 414 ? 177.188 212.728 172.208 1.00 63.47  ? 458 ASN C CA  1 
ATOM   9303  C C   . ASN C 3 414 ? 178.688 212.971 172.375 1.00 63.47  ? 458 ASN C C   1 
ATOM   9304  O O   . ASN C 3 414 ? 179.220 213.097 173.479 1.00 63.47  ? 458 ASN C O   1 
ATOM   9305  C CB  . ASN C 3 414 ? 176.410 213.111 173.464 1.00 63.47  ? 458 ASN C CB  1 
ATOM   9306  C CG  . ASN C 3 414 ? 176.517 212.067 174.558 1.00 63.47  ? 458 ASN C CG  1 
ATOM   9307  O OD1 . ASN C 3 414 ? 177.283 211.110 174.447 1.00 63.47  ? 458 ASN C OD1 1 
ATOM   9308  N ND2 . ASN C 3 414 ? 175.751 212.250 175.626 1.00 63.47  ? 458 ASN C ND2 1 
ATOM   9309  N N   . PHE C 3 415 ? 179.370 213.039 171.232 1.00 53.37  ? 459 PHE C N   1 
ATOM   9310  C CA  . PHE C 3 415 ? 180.804 213.297 171.183 1.00 53.37  ? 459 PHE C CA  1 
ATOM   9311  C C   . PHE C 3 415 ? 181.117 214.753 170.853 1.00 53.37  ? 459 PHE C C   1 
ATOM   9312  O O   . PHE C 3 415 ? 182.136 215.041 170.216 1.00 53.37  ? 459 PHE C O   1 
ATOM   9313  C CB  . PHE C 3 415 ? 181.474 212.368 170.171 1.00 53.37  ? 459 PHE C CB  1 
ATOM   9314  C CG  . PHE C 3 415 ? 181.080 210.926 170.318 1.00 53.37  ? 459 PHE C CG  1 
ATOM   9315  C CD1 . PHE C 3 415 ? 181.550 210.170 171.379 1.00 53.37  ? 459 PHE C CD1 1 
ATOM   9316  C CD2 . PHE C 3 415 ? 180.242 210.326 169.394 1.00 53.37  ? 459 PHE C CD2 1 
ATOM   9317  C CE1 . PHE C 3 415 ? 181.191 208.843 171.515 1.00 53.37  ? 459 PHE C CE1 1 
ATOM   9318  C CE2 . PHE C 3 415 ? 179.880 208.999 169.525 1.00 53.37  ? 459 PHE C CE2 1 
ATOM   9319  C CZ  . PHE C 3 415 ? 180.354 208.257 170.587 1.00 53.37  ? 459 PHE C CZ  1 
ATOM   9320  N N   . ALA C 3 416 ? 180.258 215.681 171.279 1.00 46.86  ? 460 ALA C N   1 
ATOM   9321  C CA  . ALA C 3 416 ? 180.439 217.091 170.956 1.00 46.86  ? 460 ALA C CA  1 
ATOM   9322  C C   . ALA C 3 416 ? 181.642 217.714 171.651 1.00 46.86  ? 460 ALA C C   1 
ATOM   9323  O O   . ALA C 3 416 ? 182.070 218.801 171.248 1.00 46.86  ? 460 ALA C O   1 
ATOM   9324  C CB  . ALA C 3 416 ? 179.176 217.876 171.313 1.00 46.86  ? 460 ALA C CB  1 
ATOM   9325  N N   . LYS C 3 417 ? 182.196 217.063 172.672 1.00 51.11  ? 461 LYS C N   1 
ATOM   9326  C CA  . LYS C 3 417 ? 183.339 217.595 173.399 1.00 51.11  ? 461 LYS C CA  1 
ATOM   9327  C C   . LYS C 3 417 ? 184.663 216.974 172.978 1.00 51.11  ? 461 LYS C C   1 
ATOM   9328  O O   . LYS C 3 417 ? 185.719 217.501 173.343 1.00 51.11  ? 461 LYS C O   1 
ATOM   9329  C CB  . LYS C 3 417 ? 183.144 217.398 174.908 1.00 51.11  ? 461 LYS C CB  1 
ATOM   9330  C CG  . LYS C 3 417 ? 181.888 218.050 175.462 1.00 51.11  ? 461 LYS C CG  1 
ATOM   9331  C CD  . LYS C 3 417 ? 181.733 217.776 176.949 1.00 51.11  ? 461 LYS C CD  1 
ATOM   9332  C CE  . LYS C 3 417 ? 180.465 218.408 177.498 1.00 51.11  ? 461 LYS C CE  1 
ATOM   9333  N NZ  . LYS C 3 417 ? 180.288 218.127 178.949 1.00 51.11  ? 461 LYS C NZ  1 
ATOM   9334  N N   . ILE C 3 418 ? 184.636 215.877 172.224 1.00 48.41  ? 462 ILE C N   1 
ATOM   9335  C CA  . ILE C 3 418 ? 185.844 215.195 171.785 1.00 48.41  ? 462 ILE C CA  1 
ATOM   9336  C C   . ILE C 3 418 ? 185.893 215.215 170.261 1.00 48.41  ? 462 ILE C C   1 
ATOM   9337  O O   . ILE C 3 418 ? 184.917 215.543 169.587 1.00 48.41  ? 462 ILE C O   1 
ATOM   9338  C CB  . ILE C 3 418 ? 185.929 213.752 172.318 1.00 48.41  ? 462 ILE C CB  1 
ATOM   9339  C CG1 . ILE C 3 418 ? 184.738 212.931 171.823 1.00 48.41  ? 462 ILE C CG1 1 
ATOM   9340  C CG2 . ILE C 3 418 ? 185.989 213.748 173.837 1.00 48.41  ? 462 ILE C CG2 1 
ATOM   9341  C CD1 . ILE C 3 418 ? 184.771 211.484 172.263 1.00 48.41  ? 462 ILE C CD1 1 
ATOM   9342  N N   . ASN C 3 419 ? 187.055 214.856 169.725 1.00 58.61  ? 463 ASN C N   1 
ATOM   9343  C CA  . ASN C 3 419 ? 187.287 214.823 168.290 1.00 58.61  ? 463 ASN C CA  1 
ATOM   9344  C C   . ASN C 3 419 ? 187.490 213.388 167.820 1.00 58.61  ? 463 ASN C C   1 
ATOM   9345  O O   . ASN C 3 419 ? 187.743 212.478 168.613 1.00 58.61  ? 463 ASN C O   1 
ATOM   9346  C CB  . ASN C 3 419 ? 188.502 215.677 167.912 1.00 58.61  ? 463 ASN C CB  1 
ATOM   9347  C CG  . ASN C 3 419 ? 188.331 217.133 168.293 1.00 58.61  ? 463 ASN C CG  1 
ATOM   9348  O OD1 . ASN C 3 419 ? 187.222 217.668 168.265 1.00 58.61  ? 463 ASN C OD1 1 
ATOM   9349  N ND2 . ASN C 3 419 ? 189.431 217.784 168.654 1.00 58.61  ? 463 ASN C ND2 1 
ATOM   9350  N N   . PHE C 3 420 ? 187.374 213.199 166.509 1.00 56.57  ? 464 PHE C N   1 
ATOM   9351  C CA  . PHE C 3 420 ? 187.506 211.892 165.887 1.00 56.57  ? 464 PHE C CA  1 
ATOM   9352  C C   . PHE C 3 420 ? 188.724 211.864 164.974 1.00 56.57  ? 464 PHE C C   1 
ATOM   9353  O O   . PHE C 3 420 ? 189.046 212.852 164.308 1.00 56.57  ? 464 PHE C O   1 
ATOM   9354  C CB  . PHE C 3 420 ? 186.252 211.531 165.082 1.00 56.57  ? 464 PHE C CB  1 
ATOM   9355  C CG  . PHE C 3 420 ? 185.140 210.960 165.911 1.00 56.57  ? 464 PHE C CG  1 
ATOM   9356  C CD1 . PHE C 3 420 ? 185.064 209.598 166.148 1.00 56.57  ? 464 PHE C CD1 1 
ATOM   9357  C CD2 . PHE C 3 420 ? 184.167 211.784 166.450 1.00 56.57  ? 464 PHE C CD2 1 
ATOM   9358  C CE1 . PHE C 3 420 ? 184.041 209.068 166.909 1.00 56.57  ? 464 PHE C CE1 1 
ATOM   9359  C CE2 . PHE C 3 420 ? 183.141 211.260 167.211 1.00 56.57  ? 464 PHE C CE2 1 
ATOM   9360  C CZ  . PHE C 3 420 ? 183.078 209.900 167.441 1.00 56.57  ? 464 PHE C CZ  1 
ATOM   9361  N N   . LEU C 3 421 ? 189.400 210.715 164.951 1.00 54.59  ? 465 LEU C N   1 
ATOM   9362  C CA  . LEU C 3 421 ? 190.532 210.464 164.057 1.00 54.59  ? 465 LEU C CA  1 
ATOM   9363  C C   . LEU C 3 421 ? 190.146 209.273 163.184 1.00 54.59  ? 465 LEU C C   1 
ATOM   9364  O O   . LEU C 3 421 ? 190.428 208.122 163.526 1.00 54.59  ? 465 LEU C O   1 
ATOM   9365  C CB  . LEU C 3 421 ? 191.816 210.206 164.841 1.00 54.59  ? 465 LEU C CB  1 
ATOM   9366  C CG  . LEU C 3 421 ? 193.086 209.998 164.012 1.00 54.59  ? 465 LEU C CG  1 
ATOM   9367  C CD1 . LEU C 3 421 ? 193.400 211.236 163.188 1.00 54.59  ? 465 LEU C CD1 1 
ATOM   9368  C CD2 . LEU C 3 421 ? 194.258 209.635 164.909 1.00 54.59  ? 465 LEU C CD2 1 
ATOM   9369  N N   . CYS C 3 422 ? 189.495 209.555 162.059 1.00 63.04  ? 466 CYS C N   1 
ATOM   9370  C CA  . CYS C 3 422 ? 188.974 208.516 161.184 1.00 63.04  ? 466 CYS C CA  1 
ATOM   9371  C C   . CYS C 3 422 ? 189.998 208.172 160.111 1.00 63.04  ? 466 CYS C C   1 
ATOM   9372  O O   . CYS C 3 422 ? 190.602 209.066 159.509 1.00 63.04  ? 466 CYS C O   1 
ATOM   9373  C CB  . CYS C 3 422 ? 187.662 208.966 160.543 1.00 63.04  ? 466 CYS C CB  1 
ATOM   9374  S SG  . CYS C 3 422 ? 186.379 209.425 161.734 1.00 63.04  ? 466 CYS C SG  1 
ATOM   9375  N N   . GLU C 3 423 ? 190.190 206.877 159.876 1.00 65.82  ? 467 GLU C N   1 
ATOM   9376  C CA  . GLU C 3 423 ? 191.152 206.395 158.893 1.00 65.82  ? 467 GLU C CA  1 
ATOM   9377  C C   . GLU C 3 423 ? 190.413 205.924 157.646 1.00 65.82  ? 467 GLU C C   1 
ATOM   9378  O O   . GLU C 3 423 ? 189.574 205.020 157.720 1.00 65.82  ? 467 GLU C O   1 
ATOM   9379  C CB  . GLU C 3 423 ? 191.998 205.265 159.477 1.00 65.82  ? 467 GLU C CB  1 
ATOM   9380  C CG  . GLU C 3 423 ? 193.105 204.781 158.558 1.00 65.82  ? 467 GLU C CG  1 
ATOM   9381  C CD  . GLU C 3 423 ? 193.857 203.597 159.131 1.00 65.82  ? 467 GLU C CD  1 
ATOM   9382  O OE1 . GLU C 3 423 ? 193.309 202.920 160.026 1.00 65.82  ? 467 GLU C OE1 1 
ATOM   9383  O OE2 . GLU C 3 423 ? 194.996 203.343 158.685 1.00 65.82  ? 467 GLU C OE2 1 
ATOM   9384  N N   . ILE C 3 424 ? 190.727 206.533 156.507 1.00 72.91  ? 468 ILE C N   1 
ATOM   9385  C CA  . ILE C 3 424 ? 190.117 206.188 155.228 1.00 72.91  ? 468 ILE C CA  1 
ATOM   9386  C C   . ILE C 3 424 ? 191.094 205.316 154.452 1.00 72.91  ? 468 ILE C C   1 
ATOM   9387  O O   . ILE C 3 424 ? 192.228 205.729 154.182 1.00 72.91  ? 468 ILE C O   1 
ATOM   9388  C CB  . ILE C 3 424 ? 189.741 207.444 154.426 1.00 72.91  ? 468 ILE C CB  1 
ATOM   9389  C CG1 . ILE C 3 424 ? 188.707 208.275 155.188 1.00 72.91  ? 468 ILE C CG1 1 
ATOM   9390  C CG2 . ILE C 3 424 ? 189.217 207.059 153.051 1.00 72.91  ? 468 ILE C CG2 1 
ATOM   9391  C CD1 . ILE C 3 424 ? 188.306 209.550 154.478 1.00 72.91  ? 468 ILE C CD1 1 
ATOM   9392  N N   . GLU C 3 425 ? 190.657 204.114 154.092 1.00 78.76  ? 469 GLU C N   1 
ATOM   9393  C CA  . GLU C 3 425 ? 191.478 203.171 153.344 1.00 78.76  ? 469 GLU C CA  1 
ATOM   9394  C C   . GLU C 3 425 ? 191.115 203.237 151.866 1.00 78.76  ? 469 GLU C C   1 
ATOM   9395  O O   . GLU C 3 425 ? 189.946 203.075 151.501 1.00 78.76  ? 469 GLU C O   1 
ATOM   9396  C CB  . GLU C 3 425 ? 191.291 201.748 153.870 1.00 78.76  ? 469 GLU C CB  1 
ATOM   9397  C CG  . GLU C 3 425 ? 191.985 200.686 153.036 1.00 78.76  ? 469 GLU C CG  1 
ATOM   9398  C CD  . GLU C 3 425 ? 191.734 199.285 153.555 1.00 78.76  ? 469 GLU C CD  1 
ATOM   9399  O OE1 . GLU C 3 425 ? 191.270 199.151 154.706 1.00 78.76  ? 469 GLU C OE1 1 
ATOM   9400  O OE2 . GLU C 3 425 ? 192.000 198.317 152.812 1.00 78.76  ? 469 GLU C OE2 1 
ATOM   9401  N N   . ILE C 3 426 ? 192.117 203.472 151.025 1.00 85.57  ? 470 ILE C N   1 
ATOM   9402  C CA  . ILE C 3 426 ? 191.940 203.560 149.580 1.00 85.57  ? 470 ILE C CA  1 
ATOM   9403  C C   . ILE C 3 426 ? 192.473 202.269 148.975 1.00 85.57  ? 470 ILE C C   1 
ATOM   9404  O O   . ILE C 3 426 ? 193.678 201.996 149.032 1.00 85.57  ? 470 ILE C O   1 
ATOM   9405  C CB  . ILE C 3 426 ? 192.650 204.785 148.989 1.00 85.57  ? 470 ILE C CB  1 
ATOM   9406  C CG1 . ILE C 3 426 ? 192.060 206.075 149.562 1.00 85.57  ? 470 ILE C CG1 1 
ATOM   9407  C CG2 . ILE C 3 426 ? 192.550 204.777 147.471 1.00 85.57  ? 470 ILE C CG2 1 
ATOM   9408  C CD1 . ILE C 3 426 ? 190.547 206.118 149.548 1.00 85.57  ? 470 ILE C CD1 1 
ATOM   9409  N N   . LYS C 3 427 ? 191.580 201.472 148.396 1.00 81.08  ? 471 LYS C N   1 
ATOM   9410  C CA  . LYS C 3 427 ? 191.935 200.192 147.790 1.00 81.08  ? 471 LYS C CA  1 
ATOM   9411  C C   . LYS C 3 427 ? 191.677 200.283 146.289 1.00 81.08  ? 471 LYS C C   1 
ATOM   9412  O O   . LYS C 3 427 ? 190.541 200.128 145.834 1.00 81.08  ? 471 LYS C O   1 
ATOM   9413  C CB  . LYS C 3 427 ? 191.146 199.050 148.423 1.00 81.08  ? 471 LYS C CB  1 
ATOM   9414  C CG  . LYS C 3 427 ? 191.550 197.673 147.924 1.00 81.08  ? 471 LYS C CG  1 
ATOM   9415  C CD  . LYS C 3 427 ? 190.795 196.575 148.653 1.00 81.08  ? 471 LYS C CD  1 
ATOM   9416  C CE  . LYS C 3 427 ? 191.229 195.200 148.174 1.00 81.08  ? 471 LYS C CE  1 
ATOM   9417  N NZ  . LYS C 3 427 ? 190.520 194.110 148.900 1.00 81.08  ? 471 LYS C NZ  1 
ATOM   9418  N N   . LYS C 3 428 ? 192.737 200.536 145.527 1.00 111.05 ? 472 LYS C N   1 
ATOM   9419  C CA  . LYS C 3 428 ? 192.658 200.572 144.075 1.00 111.05 ? 472 LYS C CA  1 
ATOM   9420  C C   . LYS C 3 428 ? 192.964 199.191 143.508 1.00 111.05 ? 472 LYS C C   1 
ATOM   9421  O O   . LYS C 3 428 ? 193.865 198.497 143.987 1.00 111.05 ? 472 LYS C O   1 
ATOM   9422  C CB  . LYS C 3 428 ? 193.630 201.610 143.510 1.00 111.05 ? 472 LYS C CB  1 
ATOM   9423  C CG  . LYS C 3 428 ? 193.844 201.530 142.007 1.00 111.05 ? 472 LYS C CG  1 
ATOM   9424  C CD  . LYS C 3 428 ? 194.916 202.506 141.551 1.00 111.05 ? 472 LYS C CD  1 
ATOM   9425  C CE  . LYS C 3 428 ? 195.163 202.395 140.055 1.00 111.05 ? 472 LYS C CE  1 
ATOM   9426  N NZ  . LYS C 3 428 ? 196.245 203.314 139.602 1.00 111.05 ? 472 LYS C NZ  1 
ATOM   9427  N N   . SER C 3 429 ? 192.201 198.797 142.490 1.00 124.04 ? 473 SER C N   1 
ATOM   9428  C CA  . SER C 3 429 ? 192.353 197.471 141.905 1.00 124.04 ? 473 SER C CA  1 
ATOM   9429  C C   . SER C 3 429 ? 193.733 197.307 141.280 1.00 124.04 ? 473 SER C C   1 
ATOM   9430  O O   . SER C 3 429 ? 194.195 198.171 140.528 1.00 124.04 ? 473 SER C O   1 
ATOM   9431  C CB  . SER C 3 429 ? 191.265 197.233 140.857 1.00 124.04 ? 473 SER C CB  1 
ATOM   9432  O OG  . SER C 3 429 ? 189.998 197.650 141.335 1.00 124.04 ? 473 SER C OG  1 
ATOM   9433  N N   . ASN C 3 430 ? 194.387 196.189 141.600 1.00 125.29 ? 474 ASN C N   1 
ATOM   9434  C CA  . ASN C 3 430 ? 195.709 195.842 141.075 1.00 125.29 ? 474 ASN C CA  1 
ATOM   9435  C C   . ASN C 3 430 ? 196.733 196.930 141.411 1.00 125.29 ? 474 ASN C C   1 
ATOM   9436  O O   . ASN C 3 430 ? 197.322 197.568 140.536 1.00 125.29 ? 474 ASN C O   1 
ATOM   9437  C CB  . ASN C 3 430 ? 195.644 195.578 139.565 1.00 125.29 ? 474 ASN C CB  1 
ATOM   9438  C CG  . ASN C 3 430 ? 196.951 195.045 139.007 1.00 125.29 ? 474 ASN C CG  1 
ATOM   9439  O OD1 . ASN C 3 430 ? 197.711 195.774 138.369 1.00 125.29 ? 474 ASN C OD1 1 
ATOM   9440  N ND2 . ASN C 3 430 ? 197.217 193.766 139.244 1.00 125.29 ? 474 ASN C ND2 1 
ATOM   9441  N N   . SER C 3 431 ? 196.928 197.134 142.709 1.00 116.77 ? 475 SER C N   1 
ATOM   9442  C CA  . SER C 3 431 ? 197.884 198.112 143.215 1.00 116.77 ? 475 SER C CA  1 
ATOM   9443  C C   . SER C 3 431 ? 198.155 197.796 144.682 1.00 116.77 ? 475 SER C C   1 
ATOM   9444  O O   . SER C 3 431 ? 197.765 196.739 145.190 1.00 116.77 ? 475 SER C O   1 
ATOM   9445  C CB  . SER C 3 431 ? 197.362 199.540 143.028 1.00 116.77 ? 475 SER C CB  1 
ATOM   9446  O OG  . SER C 3 431 ? 196.087 199.688 143.622 1.00 116.77 ? 475 SER C OG  1 
ATOM   9447  N N   . VAL C 3 432 ? 198.824 198.717 145.364 1.00 116.97 ? 476 VAL C N   1 
ATOM   9448  C CA  . VAL C 3 432 ? 199.118 198.585 146.786 1.00 116.97 ? 476 VAL C CA  1 
ATOM   9449  C C   . VAL C 3 432 ? 198.012 199.267 147.578 1.00 116.97 ? 476 VAL C C   1 
ATOM   9450  O O   . VAL C 3 432 ? 197.482 200.306 147.166 1.00 116.97 ? 476 VAL C O   1 
ATOM   9451  C CB  . VAL C 3 432 ? 200.498 199.184 147.117 1.00 116.97 ? 476 VAL C CB  1 
ATOM   9452  C CG1 . VAL C 3 432 ? 200.902 198.849 148.546 1.00 116.97 ? 476 VAL C CG1 1 
ATOM   9453  C CG2 . VAL C 3 432 ? 201.542 198.687 146.129 1.00 116.97 ? 476 VAL C CG2 1 
ATOM   9454  N N   . GLN C 3 433 ? 197.657 198.679 148.718 1.00 107.14 ? 477 GLN C N   1 
ATOM   9455  C CA  . GLN C 3 433 ? 196.616 199.246 149.565 1.00 107.14 ? 477 GLN C CA  1 
ATOM   9456  C C   . GLN C 3 433 ? 197.071 200.582 150.139 1.00 107.14 ? 477 GLN C C   1 
ATOM   9457  O O   . GLN C 3 433 ? 198.169 200.691 150.694 1.00 107.14 ? 477 GLN C O   1 
ATOM   9458  C CB  . GLN C 3 433 ? 196.264 198.274 150.690 1.00 107.14 ? 477 GLN C CB  1 
ATOM   9459  C CG  . GLN C 3 433 ? 195.391 198.868 151.782 1.00 107.14 ? 477 GLN C CG  1 
ATOM   9460  C CD  . GLN C 3 433 ? 195.155 197.903 152.926 1.00 107.14 ? 477 GLN C CD  1 
ATOM   9461  O OE1 . GLN C 3 433 ? 195.260 196.688 152.760 1.00 107.14 ? 477 GLN C OE1 1 
ATOM   9462  N NE2 . GLN C 3 433 ? 194.836 198.440 154.098 1.00 107.14 ? 477 GLN C NE2 1 
ATOM   9463  N N   . GLU C 3 434 ? 196.224 201.599 150.005 1.00 88.16  ? 478 GLU C N   1 
ATOM   9464  C CA  . GLU C 3 434 ? 196.521 202.943 150.476 1.00 88.16  ? 478 GLU C CA  1 
ATOM   9465  C C   . GLU C 3 434 ? 195.621 203.292 151.653 1.00 88.16  ? 478 GLU C C   1 
ATOM   9466  O O   . GLU C 3 434 ? 194.440 202.930 151.674 1.00 88.16  ? 478 GLU C O   1 
ATOM   9467  C CB  . GLU C 3 434 ? 196.337 203.970 149.354 1.00 88.16  ? 478 GLU C CB  1 
ATOM   9468  C CG  . GLU C 3 434 ? 196.825 205.367 149.701 1.00 88.16  ? 478 GLU C CG  1 
ATOM   9469  C CD  . GLU C 3 434 ? 196.587 206.361 148.582 1.00 88.16  ? 478 GLU C CD  1 
ATOM   9470  O OE1 . GLU C 3 434 ? 196.586 207.579 148.857 1.00 88.16  ? 478 GLU C OE1 1 
ATOM   9471  O OE2 . GLU C 3 434 ? 196.401 205.925 147.427 1.00 88.16  ? 478 GLU C OE2 1 
ATOM   9472  N N   . GLN C 3 435 ? 196.185 203.994 152.633 1.00 89.69  ? 479 GLN C N   1 
ATOM   9473  C CA  . GLN C 3 435 ? 195.456 204.415 153.820 1.00 89.69  ? 479 GLN C CA  1 
ATOM   9474  C C   . GLN C 3 435 ? 195.616 205.915 154.011 1.00 89.69  ? 479 GLN C C   1 
ATOM   9475  O O   . GLN C 3 435 ? 196.689 206.472 153.762 1.00 89.69  ? 479 GLN C O   1 
ATOM   9476  C CB  . GLN C 3 435 ? 195.946 203.674 155.070 1.00 89.69  ? 479 GLN C CB  1 
ATOM   9477  C CG  . GLN C 3 435 ? 195.683 202.177 155.049 1.00 89.69  ? 479 GLN C CG  1 
ATOM   9478  C CD  . GLN C 3 435 ? 196.248 201.471 156.266 1.00 89.69  ? 479 GLN C CD  1 
ATOM   9479  O OE1 . GLN C 3 435 ? 197.021 202.049 157.031 1.00 89.69  ? 479 GLN C OE1 1 
ATOM   9480  N NE2 . GLN C 3 435 ? 195.865 200.213 156.452 1.00 89.69  ? 479 GLN C NE2 1 
ATOM   9481  N N   . ARG C 3 436 ? 194.542 206.564 154.456 1.00 73.48  ? 480 ARG C N   1 
ATOM   9482  C CA  . ARG C 3 436 ? 194.537 207.994 154.721 1.00 73.48  ? 480 ARG C CA  1 
ATOM   9483  C C   . ARG C 3 436 ? 193.905 208.251 156.080 1.00 73.48  ? 480 ARG C C   1 
ATOM   9484  O O   . ARG C 3 436 ? 192.940 207.583 156.461 1.00 73.48  ? 480 ARG C O   1 
ATOM   9485  C CB  . ARG C 3 436 ? 193.772 208.764 153.638 1.00 73.48  ? 480 ARG C CB  1 
ATOM   9486  C CG  . ARG C 3 436 ? 194.556 208.991 152.357 1.00 73.48  ? 480 ARG C CG  1 
ATOM   9487  C CD  . ARG C 3 436 ? 193.841 209.978 151.447 1.00 73.48  ? 480 ARG C CD  1 
ATOM   9488  N NE  . ARG C 3 436 ? 194.658 210.360 150.299 1.00 73.48  ? 480 ARG C NE  1 
ATOM   9489  C CZ  . ARG C 3 436 ? 194.332 211.318 149.438 1.00 73.48  ? 480 ARG C CZ  1 
ATOM   9490  N NH1 . ARG C 3 436 ? 193.205 211.997 149.594 1.00 73.48  ? 480 ARG C NH1 1 
ATOM   9491  N NH2 . ARG C 3 436 ? 195.135 211.599 148.421 1.00 73.48  ? 480 ARG C NH2 1 
ATOM   9492  N N   . ASN C 3 437 ? 194.453 209.221 156.807 1.00 78.49  ? 481 ASN C N   1 
ATOM   9493  C CA  . ASN C 3 437 ? 193.954 209.602 158.121 1.00 78.49  ? 481 ASN C CA  1 
ATOM   9494  C C   . ASN C 3 437 ? 193.471 211.044 158.077 1.00 78.49  ? 481 ASN C C   1 
ATOM   9495  O O   . ASN C 3 437 ? 194.173 211.924 157.568 1.00 78.49  ? 481 ASN C O   1 
ATOM   9496  C CB  . ASN C 3 437 ? 195.035 209.431 159.193 1.00 78.49  ? 481 ASN C CB  1 
ATOM   9497  C CG  . ASN C 3 437 ? 196.391 209.938 158.742 1.00 78.49  ? 481 ASN C CG  1 
ATOM   9498  O OD1 . ASN C 3 437 ? 196.552 210.396 157.611 1.00 78.49  ? 481 ASN C OD1 1 
ATOM   9499  N ND2 . ASN C 3 437 ? 197.377 209.858 159.628 1.00 78.49  ? 481 ASN C ND2 1 
ATOM   9500  N N   . VAL C 3 438 ? 192.273 211.280 158.606 1.00 64.54  ? 482 VAL C N   1 
ATOM   9501  C CA  . VAL C 3 438 ? 191.674 212.609 158.641 1.00 64.54  ? 482 VAL C CA  1 
ATOM   9502  C C   . VAL C 3 438 ? 191.048 212.822 160.011 1.00 64.54  ? 482 VAL C C   1 
ATOM   9503  O O   . VAL C 3 438 ? 190.522 211.883 160.619 1.00 64.54  ? 482 VAL C O   1 
ATOM   9504  C CB  . VAL C 3 438 ? 190.626 212.793 157.524 1.00 64.54  ? 482 VAL C CB  1 
ATOM   9505  C CG1 . VAL C 3 438 ? 191.311 213.006 156.183 1.00 64.54  ? 482 VAL C CG1 1 
ATOM   9506  C CG2 . VAL C 3 438 ? 189.695 211.592 157.465 1.00 64.54  ? 482 VAL C CG2 1 
ATOM   9507  N N   . THR C 3 439 ? 191.107 214.057 160.498 1.00 53.89  ? 483 THR C N   1 
ATOM   9508  C CA  . THR C 3 439 ? 190.571 214.417 161.802 1.00 53.89  ? 483 THR C CA  1 
ATOM   9509  C C   . THR C 3 439 ? 189.346 215.307 161.635 1.00 53.89  ? 483 THR C C   1 
ATOM   9510  O O   . THR C 3 439 ? 189.296 216.150 160.734 1.00 53.89  ? 483 THR C O   1 
ATOM   9511  C CB  . THR C 3 439 ? 191.625 215.130 162.656 1.00 53.89  ? 483 THR C CB  1 
ATOM   9512  O OG1 . THR C 3 439 ? 191.023 215.603 163.868 1.00 53.89  ? 483 THR C OG1 1 
ATOM   9513  C CG2 . THR C 3 439 ? 192.234 216.302 161.898 1.00 53.89  ? 483 THR C CG2 1 
ATOM   9514  N N   . ILE C 3 440 ? 188.357 215.107 162.505 1.00 56.16  ? 484 ILE C N   1 
ATOM   9515  C CA  . ILE C 3 440 ? 187.113 215.865 162.475 1.00 56.16  ? 484 ILE C CA  1 
ATOM   9516  C C   . ILE C 3 440 ? 186.653 216.120 163.903 1.00 56.16  ? 484 ILE C C   1 
ATOM   9517  O O   . ILE C 3 440 ? 186.859 215.297 164.799 1.00 56.16  ? 484 ILE C O   1 
ATOM   9518  C CB  . ILE C 3 440 ? 186.007 215.136 161.678 1.00 56.16  ? 484 ILE C CB  1 
ATOM   9519  C CG1 . ILE C 3 440 ? 185.898 213.679 162.131 1.00 56.16  ? 484 ILE C CG1 1 
ATOM   9520  C CG2 . ILE C 3 440 ? 186.264 215.229 160.183 1.00 56.16  ? 484 ILE C CG2 1 
ATOM   9521  C CD1 . ILE C 3 440 ? 184.769 212.919 161.478 1.00 56.16  ? 484 ILE C CD1 1 
ATOM   9522  N N   . LYS C 3 441 ? 186.023 217.274 164.109 1.00 57.74  ? 485 LYS C N   1 
ATOM   9523  C CA  . LYS C 3 441 ? 185.460 217.608 165.410 1.00 57.74  ? 485 LYS C CA  1 
ATOM   9524  C C   . LYS C 3 441 ? 184.153 216.852 165.613 1.00 57.74  ? 485 LYS C C   1 
ATOM   9525  O O   . LYS C 3 441 ? 183.251 216.918 164.772 1.00 57.74  ? 485 LYS C O   1 
ATOM   9526  C CB  . LYS C 3 441 ? 185.226 219.113 165.525 1.00 57.74  ? 485 LYS C CB  1 
ATOM   9527  C CG  . LYS C 3 441 ? 184.556 219.533 166.824 1.00 57.74  ? 485 LYS C CG  1 
ATOM   9528  C CD  . LYS C 3 441 ? 184.315 221.033 166.866 1.00 57.74  ? 485 LYS C CD  1 
ATOM   9529  C CE  . LYS C 3 441 ? 183.617 221.442 168.153 1.00 57.74  ? 485 LYS C CE  1 
ATOM   9530  N NZ  . LYS C 3 441 ? 183.380 222.910 168.217 1.00 57.74  ? 485 LYS C NZ  1 
ATOM   9531  N N   . GLY C 3 442 ? 184.055 216.135 166.728 1.00 55.86  ? 486 GLY C N   1 
ATOM   9532  C CA  . GLY C 3 442 ? 182.862 215.351 166.991 1.00 55.86  ? 486 GLY C CA  1 
ATOM   9533  C C   . GLY C 3 442 ? 181.670 216.234 167.319 1.00 55.86  ? 486 GLY C C   1 
ATOM   9534  O O   . GLY C 3 442 ? 181.795 217.271 167.972 1.00 55.86  ? 486 GLY C O   1 
ATOM   9535  N N   . VAL C 3 443 ? 180.498 215.812 166.849 1.00 54.11  ? 487 VAL C N   1 
ATOM   9536  C CA  . VAL C 3 443 ? 179.246 216.502 167.118 1.00 54.11  ? 487 VAL C CA  1 
ATOM   9537  C C   . VAL C 3 443 ? 178.271 215.508 167.740 1.00 54.11  ? 487 VAL C C   1 
ATOM   9538  O O   . VAL C 3 443 ? 178.576 214.328 167.914 1.00 54.11  ? 487 VAL C O   1 
ATOM   9539  C CB  . VAL C 3 443 ? 178.645 217.145 165.855 1.00 54.11  ? 487 VAL C CB  1 
ATOM   9540  C CG1 . VAL C 3 443 ? 179.470 218.349 165.429 1.00 54.11  ? 487 VAL C CG1 1 
ATOM   9541  C CG2 . VAL C 3 443 ? 178.563 216.128 164.734 1.00 54.11  ? 487 VAL C CG2 1 
ATOM   9542  N N   . GLU C 3 444 ? 177.083 216.005 168.075 1.00 62.81  ? 488 GLU C N   1 
ATOM   9543  C CA  . GLU C 3 444 ? 176.072 215.207 168.766 1.00 62.81  ? 488 GLU C CA  1 
ATOM   9544  C C   . GLU C 3 444 ? 175.069 214.681 167.747 1.00 62.81  ? 488 GLU C C   1 
ATOM   9545  O O   . GLU C 3 444 ? 174.189 215.414 167.289 1.00 62.81  ? 488 GLU C O   1 
ATOM   9546  C CB  . GLU C 3 444 ? 175.386 216.033 169.848 1.00 62.81  ? 488 GLU C CB  1 
ATOM   9547  C CG  . GLU C 3 444 ? 174.285 215.293 170.589 1.00 62.81  ? 488 GLU C CG  1 
ATOM   9548  C CD  . GLU C 3 444 ? 173.719 216.096 171.743 1.00 62.81  ? 488 GLU C CD  1 
ATOM   9549  O OE1 . GLU C 3 444 ? 174.408 217.024 172.217 1.00 62.81  ? 488 GLU C OE1 1 
ATOM   9550  O OE2 . GLU C 3 444 ? 172.586 215.799 172.177 1.00 62.81  ? 488 GLU C OE2 1 
ATOM   9551  N N   . ASN C 3 445 ? 175.205 213.401 167.393 1.00 71.52  ? 489 ASN C N   1 
ATOM   9552  C CA  . ASN C 3 445 ? 174.237 212.685 166.560 1.00 71.52  ? 489 ASN C CA  1 
ATOM   9553  C C   . ASN C 3 445 ? 174.034 213.381 165.211 1.00 71.52  ? 489 ASN C C   1 
ATOM   9554  O O   . ASN C 3 445 ? 172.950 213.871 164.886 1.00 71.52  ? 489 ASN C O   1 
ATOM   9555  C CB  . ASN C 3 445 ? 172.907 212.514 167.301 1.00 71.52  ? 489 ASN C CB  1 
ATOM   9556  C CG  . ASN C 3 445 ? 171.987 211.511 166.630 1.00 71.52  ? 489 ASN C CG  1 
ATOM   9557  O OD1 . ASN C 3 445 ? 172.384 210.379 166.354 1.00 71.52  ? 489 ASN C OD1 1 
ATOM   9558  N ND2 . ASN C 3 445 ? 170.750 211.921 166.364 1.00 71.52  ? 489 ASN C ND2 1 
ATOM   9559  N N   . SER C 3 446 ? 175.107 213.419 164.426 1.00 65.48  ? 490 SER C N   1 
ATOM   9560  C CA  . SER C 3 446 ? 175.061 213.981 163.085 1.00 65.48  ? 490 SER C CA  1 
ATOM   9561  C C   . SER C 3 446 ? 175.995 213.188 162.182 1.00 65.48  ? 490 SER C C   1 
ATOM   9562  O O   . SER C 3 446 ? 176.806 212.380 162.642 1.00 65.48  ? 490 SER C O   1 
ATOM   9563  C CB  . SER C 3 446 ? 175.435 215.469 163.082 1.00 65.48  ? 490 SER C CB  1 
ATOM   9564  O OG  . SER C 3 446 ? 174.779 216.163 164.128 1.00 65.48  ? 490 SER C OG  1 
ATOM   9565  N N   . SER C 3 447 ? 175.873 213.430 160.881 1.00 60.54  ? 491 SER C N   1 
ATOM   9566  C CA  . SER C 3 447 ? 176.666 212.737 159.874 1.00 60.54  ? 491 SER C CA  1 
ATOM   9567  C C   . SER C 3 447 ? 177.869 213.589 159.493 1.00 60.54  ? 491 SER C C   1 
ATOM   9568  O O   . SER C 3 447 ? 177.735 214.794 159.255 1.00 60.54  ? 491 SER C O   1 
ATOM   9569  C CB  . SER C 3 447 ? 175.824 212.426 158.637 1.00 60.54  ? 491 SER C CB  1 
ATOM   9570  O OG  . SER C 3 447 ? 174.762 211.542 158.953 1.00 60.54  ? 491 SER C OG  1 
ATOM   9571  N N   . TYR C 3 448 ? 179.040 212.959 159.439 1.00 62.25  ? 492 TYR C N   1 
ATOM   9572  C CA  . TYR C 3 448 ? 180.273 213.642 159.079 1.00 62.25  ? 492 TYR C CA  1 
ATOM   9573  C C   . TYR C 3 448 ? 180.575 213.430 157.602 1.00 62.25  ? 492 TYR C C   1 
ATOM   9574  O O   . TYR C 3 448 ? 180.346 212.346 157.058 1.00 62.25  ? 492 TYR C O   1 
ATOM   9575  C CB  . TYR C 3 448 ? 181.438 213.134 159.931 1.00 62.25  ? 492 TYR C CB  1 
ATOM   9576  C CG  . TYR C 3 448 ? 181.162 213.147 161.418 1.00 62.25  ? 492 TYR C CG  1 
ATOM   9577  C CD1 . TYR C 3 448 ? 181.522 214.235 162.200 1.00 62.25  ? 492 TYR C CD1 1 
ATOM   9578  C CD2 . TYR C 3 448 ? 180.544 212.070 162.040 1.00 62.25  ? 492 TYR C CD2 1 
ATOM   9579  C CE1 . TYR C 3 448 ? 181.274 214.251 163.559 1.00 62.25  ? 492 TYR C CE1 1 
ATOM   9580  C CE2 . TYR C 3 448 ? 180.289 212.078 163.397 1.00 62.25  ? 492 TYR C CE2 1 
ATOM   9581  C CZ  . TYR C 3 448 ? 180.656 213.171 164.152 1.00 62.25  ? 492 TYR C CZ  1 
ATOM   9582  O OH  . TYR C 3 448 ? 180.406 213.183 165.505 1.00 62.25  ? 492 TYR C OH  1 
ATOM   9583  N N   . LEU C 3 449 ? 181.094 214.473 156.956 1.00 65.49  ? 493 LEU C N   1 
ATOM   9584  C CA  . LEU C 3 449 ? 181.386 214.445 155.528 1.00 65.49  ? 493 LEU C CA  1 
ATOM   9585  C C   . LEU C 3 449 ? 182.818 214.903 155.308 1.00 65.49  ? 493 LEU C C   1 
ATOM   9586  O O   . LEU C 3 449 ? 183.172 216.033 155.658 1.00 65.49  ? 493 LEU C O   1 
ATOM   9587  C CB  . LEU C 3 449 ? 180.410 215.329 154.745 1.00 65.49  ? 493 LEU C CB  1 
ATOM   9588  C CG  . LEU C 3 449 ? 178.934 214.920 154.768 1.00 65.49  ? 493 LEU C CG  1 
ATOM   9589  C CD1 . LEU C 3 449 ? 178.189 215.612 155.902 1.00 65.49  ? 493 LEU C CD1 1 
ATOM   9590  C CD2 . LEU C 3 449 ? 178.272 215.215 153.430 1.00 65.49  ? 493 LEU C CD2 1 
ATOM   9591  N N   . VAL C 3 450 ? 183.637 214.027 154.730 1.00 77.32  ? 494 VAL C N   1 
ATOM   9592  C CA  . VAL C 3 450 ? 185.036 214.315 154.437 1.00 77.32  ? 494 VAL C CA  1 
ATOM   9593  C C   . VAL C 3 450 ? 185.297 213.980 152.976 1.00 77.32  ? 494 VAL C C   1 
ATOM   9594  O O   . VAL C 3 450 ? 184.989 212.871 152.525 1.00 77.32  ? 494 VAL C O   1 
ATOM   9595  C CB  . VAL C 3 450 ? 185.990 213.522 155.352 1.00 77.32  ? 494 VAL C CB  1 
ATOM   9596  C CG1 . VAL C 3 450 ? 187.434 213.725 154.919 1.00 77.32  ? 494 VAL C CG1 1 
ATOM   9597  C CG2 . VAL C 3 450 ? 185.802 213.937 156.801 1.00 77.32  ? 494 VAL C CG2 1 
ATOM   9598  N N   . ALA C 3 451 ? 185.861 214.934 152.242 1.00 68.56  ? 495 ALA C N   1 
ATOM   9599  C CA  . ALA C 3 451 ? 186.164 214.766 150.829 1.00 68.56  ? 495 ALA C CA  1 
ATOM   9600  C C   . ALA C 3 451 ? 187.666 214.622 150.630 1.00 68.56  ? 495 ALA C C   1 
ATOM   9601  O O   . ALA C 3 451 ? 188.457 215.328 151.263 1.00 68.56  ? 495 ALA C O   1 
ATOM   9602  C CB  . ALA C 3 451 ? 185.641 215.949 150.011 1.00 68.56  ? 495 ALA C CB  1 
ATOM   9603  N N   . LEU C 3 452 ? 188.053 213.703 149.750 1.00 67.06  ? 496 LEU C N   1 
ATOM   9604  C CA  . LEU C 3 452 ? 189.449 213.467 149.418 1.00 67.06  ? 496 LEU C CA  1 
ATOM   9605  C C   . LEU C 3 452 ? 189.690 213.801 147.952 1.00 67.06  ? 496 LEU C C   1 
ATOM   9606  O O   . LEU C 3 452 ? 188.770 213.760 147.130 1.00 67.06  ? 496 LEU C O   1 
ATOM   9607  C CB  . LEU C 3 452 ? 189.854 212.012 149.714 1.00 67.06  ? 496 LEU C CB  1 
ATOM   9608  C CG  . LEU C 3 452 ? 189.146 210.865 148.983 1.00 67.06  ? 496 LEU C CG  1 
ATOM   9609  C CD1 . LEU C 3 452 ? 189.823 210.526 147.658 1.00 67.06  ? 496 LEU C CD1 1 
ATOM   9610  C CD2 . LEU C 3 452 ? 189.063 209.633 149.875 1.00 67.06  ? 496 LEU C CD2 1 
ATOM   9611  N N   . ASP C 3 453 ? 190.938 214.129 147.631 1.00 74.83  ? 497 ASP C N   1 
ATOM   9612  C CA  . ASP C 3 453 ? 191.318 214.506 146.277 1.00 74.83  ? 497 ASP C CA  1 
ATOM   9613  C C   . ASP C 3 453 ? 192.676 213.884 145.967 1.00 74.83  ? 497 ASP C C   1 
ATOM   9614  O O   . ASP C 3 453 ? 193.162 213.013 146.695 1.00 74.83  ? 497 ASP C O   1 
ATOM   9615  C CB  . ASP C 3 453 ? 191.325 216.033 146.121 1.00 74.83  ? 497 ASP C CB  1 
ATOM   9616  C CG  . ASP C 3 453 ? 192.035 216.733 147.264 1.00 74.83  ? 497 ASP C CG  1 
ATOM   9617  O OD1 . ASP C 3 453 ? 192.462 216.043 148.213 1.00 74.83  ? 497 ASP C OD1 1 
ATOM   9618  O OD2 . ASP C 3 453 ? 192.166 217.974 147.212 1.00 74.83  ? 497 ASP C OD2 1 
ATOM   9619  N N   . LYS C 3 454 ? 193.284 214.338 144.870 1.00 71.42  ? 498 LYS C N   1 
ATOM   9620  C CA  . LYS C 3 454 ? 194.591 213.862 144.416 1.00 71.42  ? 498 LYS C CA  1 
ATOM   9621  C C   . LYS C 3 454 ? 194.571 212.349 144.177 1.00 71.42  ? 498 LYS C C   1 
ATOM   9622  O O   . LYS C 3 454 ? 195.268 211.573 144.834 1.00 71.42  ? 498 LYS C O   1 
ATOM   9623  C CB  . LYS C 3 454 ? 195.693 214.256 145.406 1.00 71.42  ? 498 LYS C CB  1 
ATOM   9624  C CG  . LYS C 3 454 ? 197.097 214.208 144.824 1.00 71.42  ? 498 LYS C CG  1 
ATOM   9625  C CD  . LYS C 3 454 ? 197.245 215.175 143.662 1.00 71.42  ? 498 LYS C CD  1 
ATOM   9626  C CE  . LYS C 3 454 ? 197.079 216.616 144.118 1.00 71.42  ? 498 LYS C CE  1 
ATOM   9627  N NZ  . LYS C 3 454 ? 198.072 216.986 145.165 1.00 71.42  ? 498 LYS C NZ  1 
ATOM   9628  N N   . LEU C 3 455 ? 193.745 211.943 143.215 1.00 88.54  ? 499 LEU C N   1 
ATOM   9629  C CA  . LEU C 3 455 ? 193.642 210.546 142.820 1.00 88.54  ? 499 LEU C CA  1 
ATOM   9630  C C   . LEU C 3 455 ? 193.554 210.464 141.303 1.00 88.54  ? 499 LEU C C   1 
ATOM   9631  O O   . LEU C 3 455 ? 193.223 211.440 140.625 1.00 88.54  ? 499 LEU C O   1 
ATOM   9632  C CB  . LEU C 3 455 ? 192.429 209.852 143.461 1.00 88.54  ? 499 LEU C CB  1 
ATOM   9633  C CG  . LEU C 3 455 ? 191.035 210.171 142.911 1.00 88.54  ? 499 LEU C CG  1 
ATOM   9634  C CD1 . LEU C 3 455 ? 190.042 209.106 143.348 1.00 88.54  ? 499 LEU C CD1 1 
ATOM   9635  C CD2 . LEU C 3 455 ? 190.563 211.547 143.356 1.00 88.54  ? 499 LEU C CD2 1 
ATOM   9636  N N   . ASN C 3 456 ? 193.855 209.283 140.778 1.00 107.05 ? 500 ASN C N   1 
ATOM   9637  C CA  . ASN C 3 456 ? 193.838 209.077 139.334 1.00 107.05 ? 500 ASN C CA  1 
ATOM   9638  C C   . ASN C 3 456 ? 192.409 208.833 138.858 1.00 107.05 ? 500 ASN C C   1 
ATOM   9639  O O   . ASN C 3 456 ? 191.688 208.037 139.467 1.00 107.05 ? 500 ASN C O   1 
ATOM   9640  C CB  . ASN C 3 456 ? 194.727 207.899 138.949 1.00 107.05 ? 500 ASN C CB  1 
ATOM   9641  C CG  . ASN C 3 456 ? 196.166 208.088 139.387 1.00 107.05 ? 500 ASN C CG  1 
ATOM   9642  O OD1 . ASN C 3 456 ? 196.459 208.906 140.259 1.00 107.05 ? 500 ASN C OD1 1 
ATOM   9643  N ND2 . ASN C 3 456 ? 197.074 207.331 138.782 1.00 107.05 ? 500 ASN C ND2 1 
ATOM   9644  N N   . PRO C 3 457 ? 191.971 209.489 137.789 1.00 120.80 ? 501 PRO C N   1 
ATOM   9645  C CA  . PRO C 3 457 ? 190.605 209.291 137.299 1.00 120.80 ? 501 PRO C CA  1 
ATOM   9646  C C   . PRO C 3 457 ? 190.468 207.974 136.544 1.00 120.80 ? 501 PRO C C   1 
ATOM   9647  O O   . PRO C 3 457 ? 191.448 207.305 136.214 1.00 120.80 ? 501 PRO C O   1 
ATOM   9648  C CB  . PRO C 3 457 ? 190.391 210.487 136.369 1.00 120.80 ? 501 PRO C CB  1 
ATOM   9649  C CG  . PRO C 3 457 ? 191.759 210.803 135.866 1.00 120.80 ? 501 PRO C CG  1 
ATOM   9650  C CD  . PRO C 3 457 ? 192.708 210.486 136.994 1.00 120.80 ? 501 PRO C CD  1 
ATOM   9651  N N   . TYR C 3 458 ? 189.213 207.617 136.273 1.00 147.24 ? 502 TYR C N   1 
ATOM   9652  C CA  . TYR C 3 458 ? 188.858 206.388 135.566 1.00 147.24 ? 502 TYR C CA  1 
ATOM   9653  C C   . TYR C 3 458 ? 189.464 205.166 136.257 1.00 147.24 ? 502 TYR C C   1 
ATOM   9654  O O   . TYR C 3 458 ? 190.299 204.447 135.705 1.00 147.24 ? 502 TYR C O   1 
ATOM   9655  C CB  . TYR C 3 458 ? 189.279 206.458 134.095 1.00 147.24 ? 502 TYR C CB  1 
ATOM   9656  C CG  . TYR C 3 458 ? 188.653 205.387 133.231 1.00 147.24 ? 502 TYR C CG  1 
ATOM   9657  C CD1 . TYR C 3 458 ? 189.414 204.343 132.722 1.00 147.24 ? 502 TYR C CD1 1 
ATOM   9658  C CD2 . TYR C 3 458 ? 187.298 205.418 132.926 1.00 147.24 ? 502 TYR C CD2 1 
ATOM   9659  C CE1 . TYR C 3 458 ? 188.845 203.362 131.932 1.00 147.24 ? 502 TYR C CE1 1 
ATOM   9660  C CE2 . TYR C 3 458 ? 186.721 204.442 132.137 1.00 147.24 ? 502 TYR C CE2 1 
ATOM   9661  C CZ  . TYR C 3 458 ? 187.498 203.416 131.643 1.00 147.24 ? 502 TYR C CZ  1 
ATOM   9662  O OH  . TYR C 3 458 ? 186.927 202.442 130.858 1.00 147.24 ? 502 TYR C OH  1 
ATOM   9663  N N   . THR C 3 459 ? 189.029 204.947 137.496 1.00 123.11 ? 503 THR C N   1 
ATOM   9664  C CA  . THR C 3 459 ? 189.524 203.834 138.293 1.00 123.11 ? 503 THR C CA  1 
ATOM   9665  C C   . THR C 3 459 ? 188.475 203.458 139.328 1.00 123.11 ? 503 THR C C   1 
ATOM   9666  O O   . THR C 3 459 ? 187.958 204.328 140.034 1.00 123.11 ? 503 THR C O   1 
ATOM   9667  C CB  . THR C 3 459 ? 190.847 204.190 138.984 1.00 123.11 ? 503 THR C CB  1 
ATOM   9668  O OG1 . THR C 3 459 ? 191.844 204.481 137.997 1.00 123.11 ? 503 THR C OG1 1 
ATOM   9669  C CG2 . THR C 3 459 ? 191.324 203.035 139.850 1.00 123.11 ? 503 THR C CG2 1 
ATOM   9670  N N   . LEU C 3 460 ? 188.162 202.167 139.407 1.00 119.00 ? 504 LEU C N   1 
ATOM   9671  C CA  . LEU C 3 460 ? 187.237 201.672 140.415 1.00 119.00 ? 504 LEU C CA  1 
ATOM   9672  C C   . LEU C 3 460 ? 187.936 201.571 141.764 1.00 119.00 ? 504 LEU C C   1 
ATOM   9673  O O   . LEU C 3 460 ? 189.062 201.075 141.861 1.00 119.00 ? 504 LEU C O   1 
ATOM   9674  C CB  . LEU C 3 460 ? 186.681 200.307 140.007 1.00 119.00 ? 504 LEU C CB  1 
ATOM   9675  C CG  . LEU C 3 460 ? 185.657 199.675 140.953 1.00 119.00 ? 504 LEU C CG  1 
ATOM   9676  C CD1 . LEU C 3 460 ? 184.386 200.509 141.006 1.00 119.00 ? 504 LEU C CD1 1 
ATOM   9677  C CD2 . LEU C 3 460 ? 185.349 198.246 140.534 1.00 119.00 ? 504 LEU C CD2 1 
ATOM   9678  N N   . TYR C 3 461 ? 187.261 202.045 142.808 1.00 108.15 ? 505 TYR C N   1 
ATOM   9679  C CA  . TYR C 3 461 ? 187.813 202.052 144.154 1.00 108.15 ? 505 TYR C CA  1 
ATOM   9680  C C   . TYR C 3 461 ? 186.848 201.373 145.115 1.00 108.15 ? 505 TYR C C   1 
ATOM   9681  O O   . TYR C 3 461 ? 185.638 201.326 144.879 1.00 108.15 ? 505 TYR C O   1 
ATOM   9682  C CB  . TYR C 3 461 ? 188.101 203.480 144.637 1.00 108.15 ? 505 TYR C CB  1 
ATOM   9683  C CG  . TYR C 3 461 ? 189.283 204.138 143.962 1.00 108.15 ? 505 TYR C CG  1 
ATOM   9684  C CD1 . TYR C 3 461 ? 190.578 203.905 144.404 1.00 108.15 ? 505 TYR C CD1 1 
ATOM   9685  C CD2 . TYR C 3 461 ? 189.102 204.998 142.888 1.00 108.15 ? 505 TYR C CD2 1 
ATOM   9686  C CE1 . TYR C 3 461 ? 191.661 204.507 143.792 1.00 108.15 ? 505 TYR C CE1 1 
ATOM   9687  C CE2 . TYR C 3 461 ? 190.179 205.605 142.269 1.00 108.15 ? 505 TYR C CE2 1 
ATOM   9688  C CZ  . TYR C 3 461 ? 191.455 205.356 142.725 1.00 108.15 ? 505 TYR C CZ  1 
ATOM   9689  O OH  . TYR C 3 461 ? 192.530 205.957 142.113 1.00 108.15 ? 505 TYR C OH  1 
ATOM   9690  N N   . THR C 3 462 ? 187.402 200.848 146.205 1.00 77.78  ? 506 THR C N   1 
ATOM   9691  C CA  . THR C 3 462 ? 186.628 200.241 147.281 1.00 77.78  ? 506 THR C CA  1 
ATOM   9692  C C   . THR C 3 462 ? 186.926 201.000 148.565 1.00 77.78  ? 506 THR C C   1 
ATOM   9693  O O   . THR C 3 462 ? 188.073 201.021 149.024 1.00 77.78  ? 506 THR C O   1 
ATOM   9694  C CB  . THR C 3 462 ? 186.965 198.757 147.440 1.00 77.78  ? 506 THR C CB  1 
ATOM   9695  O OG1 . THR C 3 462 ? 186.666 198.064 146.222 1.00 77.78  ? 506 THR C OG1 1 
ATOM   9696  C CG2 . THR C 3 462 ? 186.157 198.148 148.575 1.00 77.78  ? 506 THR C CG2 1 
ATOM   9697  N N   . PHE C 3 463 ? 185.899 201.618 149.140 1.00 79.10  ? 507 PHE C N   1 
ATOM   9698  C CA  . PHE C 3 463 ? 186.053 202.492 150.294 1.00 79.10  ? 507 PHE C CA  1 
ATOM   9699  C C   . PHE C 3 463 ? 185.524 201.808 151.547 1.00 79.10  ? 507 PHE C C   1 
ATOM   9700  O O   . PHE C 3 463 ? 184.396 201.306 151.559 1.00 79.10  ? 507 PHE C O   1 
ATOM   9701  C CB  . PHE C 3 463 ? 185.322 203.819 150.076 1.00 79.10  ? 507 PHE C CB  1 
ATOM   9702  C CG  . PHE C 3 463 ? 185.811 204.594 148.887 1.00 79.10  ? 507 PHE C CG  1 
ATOM   9703  C CD1 . PHE C 3 463 ? 186.916 205.422 148.990 1.00 79.10  ? 507 PHE C CD1 1 
ATOM   9704  C CD2 . PHE C 3 463 ? 185.162 204.500 147.667 1.00 79.10  ? 507 PHE C CD2 1 
ATOM   9705  C CE1 . PHE C 3 463 ? 187.367 206.138 147.898 1.00 79.10  ? 507 PHE C CE1 1 
ATOM   9706  C CE2 . PHE C 3 463 ? 185.608 205.214 146.572 1.00 79.10  ? 507 PHE C CE2 1 
ATOM   9707  C CZ  . PHE C 3 463 ? 186.712 206.035 146.688 1.00 79.10  ? 507 PHE C CZ  1 
ATOM   9708  N N   . ARG C 3 464 ? 186.345 201.793 152.595 1.00 82.41  ? 508 ARG C N   1 
ATOM   9709  C CA  . ARG C 3 464 ? 185.919 201.355 153.915 1.00 82.41  ? 508 ARG C CA  1 
ATOM   9710  C C   . ARG C 3 464 ? 186.649 202.203 154.946 1.00 82.41  ? 508 ARG C C   1 
ATOM   9711  O O   . ARG C 3 464 ? 187.836 202.500 154.785 1.00 82.41  ? 508 ARG C O   1 
ATOM   9712  C CB  . ARG C 3 464 ? 186.191 199.863 154.142 1.00 82.41  ? 508 ARG C CB  1 
ATOM   9713  C CG  . ARG C 3 464 ? 187.650 199.454 154.025 1.00 82.41  ? 508 ARG C CG  1 
ATOM   9714  C CD  . ARG C 3 464 ? 187.837 198.001 154.429 1.00 82.41  ? 508 ARG C CD  1 
ATOM   9715  N NE  . ARG C 3 464 ? 189.245 197.638 154.546 1.00 82.41  ? 508 ARG C NE  1 
ATOM   9716  C CZ  . ARG C 3 464 ? 189.678 196.473 155.016 1.00 82.41  ? 508 ARG C CZ  1 
ATOM   9717  N NH1 . ARG C 3 464 ? 188.811 195.554 155.416 1.00 82.41  ? 508 ARG C NH1 1 
ATOM   9718  N NH2 . ARG C 3 464 ? 190.979 196.227 155.086 1.00 82.41  ? 508 ARG C NH2 1 
ATOM   9719  N N   . ILE C 3 465 ? 185.933 202.602 155.993 1.00 66.35  ? 509 ILE C N   1 
ATOM   9720  C CA  . ILE C 3 465 ? 186.455 203.545 156.974 1.00 66.35  ? 509 ILE C CA  1 
ATOM   9721  C C   . ILE C 3 465 ? 186.246 202.984 158.374 1.00 66.35  ? 509 ILE C C   1 
ATOM   9722  O O   . ILE C 3 465 ? 185.229 202.342 158.658 1.00 66.35  ? 509 ILE C O   1 
ATOM   9723  C CB  . ILE C 3 465 ? 185.794 204.934 156.824 1.00 66.35  ? 509 ILE C CB  1 
ATOM   9724  C CG1 . ILE C 3 465 ? 186.464 205.959 157.742 1.00 66.35  ? 509 ILE C CG1 1 
ATOM   9725  C CG2 . ILE C 3 465 ? 184.295 204.858 157.089 1.00 66.35  ? 509 ILE C CG2 1 
ATOM   9726  C CD1 . ILE C 3 465 ? 185.914 207.360 157.595 1.00 66.35  ? 509 ILE C CD1 1 
ATOM   9727  N N   . ARG C 3 466 ? 187.230 203.210 159.241 1.00 59.35  ? 510 ARG C N   1 
ATOM   9728  C CA  . ARG C 3 466 ? 187.115 202.912 160.661 1.00 59.35  ? 510 ARG C CA  1 
ATOM   9729  C C   . ARG C 3 466 ? 187.691 204.093 161.424 1.00 59.35  ? 510 ARG C C   1 
ATOM   9730  O O   . ARG C 3 466 ? 188.656 204.717 160.973 1.00 59.35  ? 510 ARG C O   1 
ATOM   9731  C CB  . ARG C 3 466 ? 187.838 201.612 161.034 1.00 59.35  ? 510 ARG C CB  1 
ATOM   9732  C CG  . ARG C 3 466 ? 189.330 201.615 160.751 1.00 59.35  ? 510 ARG C CG  1 
ATOM   9733  C CD  . ARG C 3 466 ? 190.046 200.578 161.599 1.00 59.35  ? 510 ARG C CD  1 
ATOM   9734  N NE  . ARG C 3 466 ? 191.496 200.667 161.465 1.00 59.35  ? 510 ARG C NE  1 
ATOM   9735  C CZ  . ARG C 3 466 ? 192.354 199.884 162.110 1.00 59.35  ? 510 ARG C CZ  1 
ATOM   9736  N NH1 . ARG C 3 466 ? 191.907 198.949 162.938 1.00 59.35  ? 510 ARG C NH1 1 
ATOM   9737  N NH2 . ARG C 3 466 ? 193.659 200.034 161.928 1.00 59.35  ? 510 ARG C NH2 1 
ATOM   9738  N N   . CYS C 3 467 ? 187.094 204.405 162.572 1.00 63.40  ? 511 CYS C N   1 
ATOM   9739  C CA  . CYS C 3 467 ? 187.428 205.638 163.265 1.00 63.40  ? 511 CYS C CA  1 
ATOM   9740  C C   . CYS C 3 467 ? 187.609 205.357 164.749 1.00 63.40  ? 511 CYS C C   1 
ATOM   9741  O O   . CYS C 3 467 ? 186.971 204.467 165.317 1.00 63.40  ? 511 CYS C O   1 
ATOM   9742  C CB  . CYS C 3 467 ? 186.348 206.703 163.042 1.00 63.40  ? 511 CYS C CB  1 
ATOM   9743  S SG  . CYS C 3 467 ? 186.860 208.391 163.415 1.00 63.40  ? 511 CYS C SG  1 
ATOM   9744  N N   . SER C 3 468 ? 188.490 206.136 165.373 1.00 58.95  ? 512 SER C N   1 
ATOM   9745  C CA  . SER C 3 468 ? 188.782 206.017 166.792 1.00 58.95  ? 512 SER C CA  1 
ATOM   9746  C C   . SER C 3 468 ? 188.869 207.405 167.412 1.00 58.95  ? 512 SER C C   1 
ATOM   9747  O O   . SER C 3 468 ? 189.056 208.408 166.718 1.00 58.95  ? 512 SER C O   1 
ATOM   9748  C CB  . SER C 3 468 ? 190.088 205.248 167.038 1.00 58.95  ? 512 SER C CB  1 
ATOM   9749  O OG  . SER C 3 468 ? 191.189 205.908 166.439 1.00 58.95  ? 512 SER C OG  1 
ATOM   9750  N N   . THR C 3 469 ? 188.732 207.451 168.734 1.00 66.41  ? 513 THR C N   1 
ATOM   9751  C CA  . THR C 3 469 ? 188.786 208.715 169.449 1.00 66.41  ? 513 THR C CA  1 
ATOM   9752  C C   . THR C 3 469 ? 190.232 209.183 169.606 1.00 66.41  ? 513 THR C C   1 
ATOM   9753  O O   . THR C 3 469 ? 191.190 208.455 169.330 1.00 66.41  ? 513 THR C O   1 
ATOM   9754  C CB  . THR C 3 469 ? 188.122 208.587 170.820 1.00 66.41  ? 513 THR C CB  1 
ATOM   9755  O OG1 . THR C 3 469 ? 188.814 207.602 171.597 1.00 66.41  ? 513 THR C OG1 1 
ATOM   9756  C CG2 . THR C 3 469 ? 186.667 208.176 170.668 1.00 66.41  ? 513 THR C CG2 1 
ATOM   9757  N N   . GLU C 3 470 ? 190.381 210.431 170.057 1.00 81.55  ? 514 GLU C N   1 
ATOM   9758  C CA  . GLU C 3 470 ? 191.712 210.988 170.276 1.00 81.55  ? 514 GLU C CA  1 
ATOM   9759  C C   . GLU C 3 470 ? 192.409 210.322 171.455 1.00 81.55  ? 514 GLU C C   1 
ATOM   9760  O O   . GLU C 3 470 ? 193.644 210.282 171.506 1.00 81.55  ? 514 GLU C O   1 
ATOM   9761  C CB  . GLU C 3 470 ? 191.615 212.499 170.492 1.00 81.55  ? 514 GLU C CB  1 
ATOM   9762  C CG  . GLU C 3 470 ? 192.954 213.215 170.560 1.00 81.55  ? 514 GLU C CG  1 
ATOM   9763  C CD  . GLU C 3 470 ? 192.807 214.725 170.567 1.00 81.55  ? 514 GLU C CD  1 
ATOM   9764  O OE1 . GLU C 3 470 ? 191.963 215.244 169.806 1.00 81.55  ? 514 GLU C OE1 1 
ATOM   9765  O OE2 . GLU C 3 470 ? 193.534 215.392 171.333 1.00 81.55  ? 514 GLU C OE2 1 
ATOM   9766  N N   . THR C 3 471 ? 191.637 209.791 172.408 1.00 82.15  ? 515 THR C N   1 
ATOM   9767  C CA  . THR C 3 471 ? 192.231 209.119 173.559 1.00 82.15  ? 515 THR C CA  1 
ATOM   9768  C C   . THR C 3 471 ? 192.982 207.858 173.143 1.00 82.15  ? 515 THR C C   1 
ATOM   9769  O O   . THR C 3 471 ? 193.912 207.431 173.838 1.00 82.15  ? 515 THR C O   1 
ATOM   9770  C CB  . THR C 3 471 ? 191.143 208.787 174.585 1.00 82.15  ? 515 THR C CB  1 
ATOM   9771  O OG1 . THR C 3 471 ? 190.408 209.977 174.900 1.00 82.15  ? 515 THR C OG1 1 
ATOM   9772  C CG2 . THR C 3 471 ? 191.750 208.236 175.868 1.00 82.15  ? 515 THR C CG2 1 
ATOM   9773  N N   . PHE C 3 472 ? 192.606 207.266 172.007 1.00 78.01  ? 516 PHE C N   1 
ATOM   9774  C CA  . PHE C 3 472 ? 193.246 206.063 171.474 1.00 78.01  ? 516 PHE C CA  1 
ATOM   9775  C C   . PHE C 3 472 ? 193.152 204.905 172.470 1.00 78.01  ? 516 PHE C C   1 
ATOM   9776  O O   . PHE C 3 472 ? 194.153 204.384 172.966 1.00 78.01  ? 516 PHE C O   1 
ATOM   9777  C CB  . PHE C 3 472 ? 194.701 206.344 171.080 1.00 78.01  ? 516 PHE C CB  1 
ATOM   9778  C CG  . PHE C 3 472 ? 195.321 205.268 170.233 1.00 78.01  ? 516 PHE C CG  1 
ATOM   9779  C CD1 . PHE C 3 472 ? 196.337 204.472 170.736 1.00 78.01  ? 516 PHE C CD1 1 
ATOM   9780  C CD2 . PHE C 3 472 ? 194.888 205.054 168.936 1.00 78.01  ? 516 PHE C CD2 1 
ATOM   9781  C CE1 . PHE C 3 472 ? 196.909 203.482 169.960 1.00 78.01  ? 516 PHE C CE1 1 
ATOM   9782  C CE2 . PHE C 3 472 ? 195.456 204.066 168.155 1.00 78.01  ? 516 PHE C CE2 1 
ATOM   9783  C CZ  . PHE C 3 472 ? 196.468 203.278 168.668 1.00 78.01  ? 516 PHE C CZ  1 
ATOM   9784  N N   . TRP C 3 473 ? 191.913 204.512 172.760 1.00 61.88  ? 517 TRP C N   1 
ATOM   9785  C CA  . TRP C 3 473 ? 191.637 203.391 173.649 1.00 61.88  ? 517 TRP C CA  1 
ATOM   9786  C C   . TRP C 3 473 ? 191.283 202.119 172.889 1.00 61.88  ? 517 TRP C C   1 
ATOM   9787  O O   . TRP C 3 473 ? 191.898 201.072 173.112 1.00 61.88  ? 517 TRP C O   1 
ATOM   9788  C CB  . TRP C 3 473 ? 190.503 203.749 174.617 1.00 61.88  ? 517 TRP C CB  1 
ATOM   9789  C CG  . TRP C 3 473 ? 189.837 202.550 175.216 1.00 61.88  ? 517 TRP C CG  1 
ATOM   9790  C CD1 . TRP C 3 473 ? 188.559 202.127 174.997 1.00 61.88  ? 517 TRP C CD1 1 
ATOM   9791  C CD2 . TRP C 3 473 ? 190.418 201.613 176.130 1.00 61.88  ? 517 TRP C CD2 1 
ATOM   9792  N NE1 . TRP C 3 473 ? 188.307 200.987 175.720 1.00 61.88  ? 517 TRP C NE1 1 
ATOM   9793  C CE2 . TRP C 3 473 ? 189.433 200.650 176.424 1.00 61.88  ? 517 TRP C CE2 1 
ATOM   9794  C CE3 . TRP C 3 473 ? 191.676 201.496 176.730 1.00 61.88  ? 517 TRP C CE3 1 
ATOM   9795  C CZ2 . TRP C 3 473 ? 189.665 199.585 177.291 1.00 61.88  ? 517 TRP C CZ2 1 
ATOM   9796  C CZ3 . TRP C 3 473 ? 191.904 200.438 177.590 1.00 61.88  ? 517 TRP C CZ3 1 
ATOM   9797  C CH2 . TRP C 3 473 ? 190.904 199.496 177.862 1.00 61.88  ? 517 TRP C CH2 1 
ATOM   9798  N N   . LYS C 3 474 ? 190.302 202.189 171.993 1.00 53.17  ? 518 LYS C N   1 
ATOM   9799  C CA  . LYS C 3 474 ? 189.888 201.040 171.204 1.00 53.17  ? 518 LYS C CA  1 
ATOM   9800  C C   . LYS C 3 474 ? 189.531 201.495 169.798 1.00 53.17  ? 518 LYS C C   1 
ATOM   9801  O O   . LYS C 3 474 ? 189.092 202.629 169.587 1.00 53.17  ? 518 LYS C O   1 
ATOM   9802  C CB  . LYS C 3 474 ? 188.694 200.315 171.841 1.00 53.17  ? 518 LYS C CB  1 
ATOM   9803  C CG  . LYS C 3 474 ? 189.085 199.280 172.882 1.00 53.17  ? 518 LYS C CG  1 
ATOM   9804  C CD  . LYS C 3 474 ? 189.883 198.148 172.256 1.00 53.17  ? 518 LYS C CD  1 
ATOM   9805  C CE  . LYS C 3 474 ? 190.238 197.089 173.286 1.00 53.17  ? 518 LYS C CE  1 
ATOM   9806  N NZ  . LYS C 3 474 ? 190.983 195.952 172.677 1.00 53.17  ? 518 LYS C NZ  1 
ATOM   9807  N N   . TRP C 3 475 ? 189.724 200.597 168.837 1.00 49.62  ? 519 TRP C N   1 
ATOM   9808  C CA  . TRP C 3 475 ? 189.445 200.870 167.435 1.00 49.62  ? 519 TRP C CA  1 
ATOM   9809  C C   . TRP C 3 475 ? 188.085 200.296 167.064 1.00 49.62  ? 519 TRP C C   1 
ATOM   9810  O O   . TRP C 3 475 ? 187.793 199.135 167.368 1.00 49.62  ? 519 TRP C O   1 
ATOM   9811  C CB  . TRP C 3 475 ? 190.529 200.274 166.537 1.00 49.62  ? 519 TRP C CB  1 
ATOM   9812  C CG  . TRP C 3 475 ? 191.637 201.226 166.217 1.00 49.62  ? 519 TRP C CG  1 
ATOM   9813  C CD1 . TRP C 3 475 ? 192.869 201.274 166.800 1.00 49.62  ? 519 TRP C CD1 1 
ATOM   9814  C CD2 . TRP C 3 475 ? 191.616 202.268 165.235 1.00 49.62  ? 519 TRP C CD2 1 
ATOM   9815  N NE1 . TRP C 3 475 ? 193.617 202.282 166.242 1.00 49.62  ? 519 TRP C NE1 1 
ATOM   9816  C CE2 . TRP C 3 475 ? 192.870 202.908 165.279 1.00 49.62  ? 519 TRP C CE2 1 
ATOM   9817  C CE3 . TRP C 3 475 ? 190.658 202.723 164.324 1.00 49.62  ? 519 TRP C CE3 1 
ATOM   9818  C CZ2 . TRP C 3 475 ? 193.192 203.977 164.447 1.00 49.62  ? 519 TRP C CZ2 1 
ATOM   9819  C CZ3 . TRP C 3 475 ? 190.980 203.785 163.498 1.00 49.62  ? 519 TRP C CZ3 1 
ATOM   9820  C CH2 . TRP C 3 475 ? 192.235 204.400 163.565 1.00 49.62  ? 519 TRP C CH2 1 
ATOM   9821  N N   . SER C 3 476 ? 187.261 201.109 166.411 1.00 51.33  ? 520 SER C N   1 
ATOM   9822  C CA  . SER C 3 476 ? 185.957 200.645 165.966 1.00 51.33  ? 520 SER C CA  1 
ATOM   9823  C C   . SER C 3 476 ? 186.110 199.626 164.841 1.00 51.33  ? 520 SER C C   1 
ATOM   9824  O O   . SER C 3 476 ? 187.139 199.552 164.163 1.00 51.33  ? 520 SER C O   1 
ATOM   9825  C CB  . SER C 3 476 ? 185.099 201.819 165.498 1.00 51.33  ? 520 SER C CB  1 
ATOM   9826  O OG  . SER C 3 476 ? 185.715 202.504 164.420 1.00 51.33  ? 520 SER C OG  1 
ATOM   9827  N N   . LYS C 3 477 ? 185.063 198.828 164.650 1.00 69.42  ? 521 LYS C N   1 
ATOM   9828  C CA  . LYS C 3 477 ? 185.077 197.819 163.604 1.00 69.42  ? 521 LYS C CA  1 
ATOM   9829  C C   . LYS C 3 477 ? 185.015 198.472 162.225 1.00 69.42  ? 521 LYS C C   1 
ATOM   9830  O O   . LYS C 3 477 ? 184.554 199.605 162.060 1.00 69.42  ? 521 LYS C O   1 
ATOM   9831  C CB  . LYS C 3 477 ? 183.908 196.850 163.777 1.00 69.42  ? 521 LYS C CB  1 
ATOM   9832  C CG  . LYS C 3 477 ? 183.885 196.142 165.121 1.00 69.42  ? 521 LYS C CG  1 
ATOM   9833  C CD  . LYS C 3 477 ? 182.699 195.199 165.228 1.00 69.42  ? 521 LYS C CD  1 
ATOM   9834  C CE  . LYS C 3 477 ? 182.692 194.470 166.562 1.00 69.42  ? 521 LYS C CE  1 
ATOM   9835  N NZ  . LYS C 3 477 ? 181.544 193.529 166.675 1.00 69.42  ? 521 LYS C NZ  1 
ATOM   9836  N N   . TRP C 3 478 ? 185.496 197.738 161.226 1.00 57.58  ? 522 TRP C N   1 
ATOM   9837  C CA  . TRP C 3 478 ? 185.461 198.227 159.856 1.00 57.58  ? 522 TRP C CA  1 
ATOM   9838  C C   . TRP C 3 478 ? 184.028 198.265 159.342 1.00 57.58  ? 522 TRP C C   1 
ATOM   9839  O O   . TRP C 3 478 ? 183.255 197.322 159.533 1.00 57.58  ? 522 TRP C O   1 
ATOM   9840  C CB  . TRP C 3 478 ? 186.317 197.344 158.951 1.00 57.58  ? 522 TRP C CB  1 
ATOM   9841  C CG  . TRP C 3 478 ? 187.787 197.444 159.219 1.00 57.58  ? 522 TRP C CG  1 
ATOM   9842  C CD1 . TRP C 3 478 ? 188.516 196.680 160.082 1.00 57.58  ? 522 TRP C CD1 1 
ATOM   9843  C CD2 . TRP C 3 478 ? 188.708 198.359 158.616 1.00 57.58  ? 522 TRP C CD2 1 
ATOM   9844  N NE1 . TRP C 3 478 ? 189.835 197.064 160.055 1.00 57.58  ? 522 TRP C NE1 1 
ATOM   9845  C CE2 . TRP C 3 478 ? 189.979 198.093 159.162 1.00 57.58  ? 522 TRP C CE2 1 
ATOM   9846  C CE3 . TRP C 3 478 ? 188.582 199.379 157.667 1.00 57.58  ? 522 TRP C CE3 1 
ATOM   9847  C CZ2 . TRP C 3 478 ? 191.116 198.808 158.791 1.00 57.58  ? 522 TRP C CZ2 1 
ATOM   9848  C CZ3 . TRP C 3 478 ? 189.711 200.088 157.301 1.00 57.58  ? 522 TRP C CZ3 1 
ATOM   9849  C CH2 . TRP C 3 478 ? 190.961 199.800 157.862 1.00 57.58  ? 522 TRP C CH2 1 
ATOM   9850  N N   . SER C 3 479 ? 183.674 199.366 158.685 1.00 83.77  ? 523 SER C N   1 
ATOM   9851  C CA  . SER C 3 479 ? 182.348 199.510 158.108 1.00 83.77  ? 523 SER C CA  1 
ATOM   9852  C C   . SER C 3 479 ? 182.244 198.689 156.824 1.00 83.77  ? 523 SER C C   1 
ATOM   9853  O O   . SER C 3 479 ? 183.218 198.096 156.350 1.00 83.77  ? 523 SER C O   1 
ATOM   9854  C CB  . SER C 3 479 ? 182.038 200.982 157.851 1.00 83.77  ? 523 SER C CB  1 
ATOM   9855  O OG  . SER C 3 479 ? 181.603 201.627 159.035 1.00 83.77  ? 523 SER C OG  1 
ATOM   9856  N N   . ASN C 3 480 ? 181.044 198.652 156.253 1.00 98.12  ? 524 ASN C N   1 
ATOM   9857  C CA  . ASN C 3 480 ? 180.823 197.892 155.030 1.00 98.12  ? 524 ASN C CA  1 
ATOM   9858  C C   . ASN C 3 480 ? 181.538 198.547 153.855 1.00 98.12  ? 524 ASN C C   1 
ATOM   9859  O O   . ASN C 3 480 ? 181.509 199.770 153.691 1.00 98.12  ? 524 ASN C O   1 
ATOM   9860  C CB  . ASN C 3 480 ? 179.327 197.777 154.740 1.00 98.12  ? 524 ASN C CB  1 
ATOM   9861  C CG  . ASN C 3 480 ? 178.566 197.105 155.864 1.00 98.12  ? 524 ASN C CG  1 
ATOM   9862  O OD1 . ASN C 3 480 ? 179.101 196.245 156.564 1.00 98.12  ? 524 ASN C OD1 1 
ATOM   9863  N ND2 . ASN C 3 480 ? 177.310 197.494 156.044 1.00 98.12  ? 524 ASN C ND2 1 
ATOM   9864  N N   . LYS C 3 481 ? 182.186 197.723 153.037 1.00 101.16 ? 525 LYS C N   1 
ATOM   9865  C CA  . LYS C 3 481 ? 182.907 198.233 151.880 1.00 101.16 ? 525 LYS C CA  1 
ATOM   9866  C C   . LYS C 3 481 ? 181.933 198.727 150.817 1.00 101.16 ? 525 LYS C C   1 
ATOM   9867  O O   . LYS C 3 481 ? 180.900 198.103 150.558 1.00 101.16 ? 525 LYS C O   1 
ATOM   9868  C CB  . LYS C 3 481 ? 183.812 197.148 151.296 1.00 101.16 ? 525 LYS C CB  1 
ATOM   9869  C CG  . LYS C 3 481 ? 184.873 196.635 152.256 1.00 101.16 ? 525 LYS C CG  1 
ATOM   9870  C CD  . LYS C 3 481 ? 185.758 195.595 151.586 1.00 101.16 ? 525 LYS C CD  1 
ATOM   9871  C CE  . LYS C 3 481 ? 186.813 195.064 152.542 1.00 101.16 ? 525 LYS C CE  1 
ATOM   9872  N NZ  . LYS C 3 481 ? 187.711 194.074 151.886 1.00 101.16 ? 525 LYS C NZ  1 
ATOM   9873  N N   . LYS C 3 482 ? 182.269 199.858 150.201 1.00 93.08  ? 526 LYS C N   1 
ATOM   9874  C CA  . LYS C 3 482 ? 181.452 200.454 149.154 1.00 93.08  ? 526 LYS C CA  1 
ATOM   9875  C C   . LYS C 3 482 ? 182.309 200.671 147.917 1.00 93.08  ? 526 LYS C C   1 
ATOM   9876  O O   . LYS C 3 482 ? 183.359 201.317 147.990 1.00 93.08  ? 526 LYS C O   1 
ATOM   9877  C CB  . LYS C 3 482 ? 180.837 201.779 149.616 1.00 93.08  ? 526 LYS C CB  1 
ATOM   9878  C CG  . LYS C 3 482 ? 179.815 201.630 150.730 1.00 93.08  ? 526 LYS C CG  1 
ATOM   9879  C CD  . LYS C 3 482 ? 178.649 200.758 150.294 1.00 93.08  ? 526 LYS C CD  1 
ATOM   9880  C CE  . LYS C 3 482 ? 177.618 200.621 151.402 1.00 93.08  ? 526 LYS C CE  1 
ATOM   9881  N NZ  . LYS C 3 482 ? 176.470 199.767 150.989 1.00 93.08  ? 526 LYS C NZ  1 
ATOM   9882  N N   . GLN C 3 483 ? 181.860 200.132 146.787 1.00 103.37 ? 527 GLN C N   1 
ATOM   9883  C CA  . GLN C 3 483 ? 182.569 200.251 145.521 1.00 103.37 ? 527 GLN C CA  1 
ATOM   9884  C C   . GLN C 3 483 ? 181.940 201.357 144.685 1.00 103.37 ? 527 GLN C C   1 
ATOM   9885  O O   . GLN C 3 483 ? 180.723 201.363 144.468 1.00 103.37 ? 527 GLN C O   1 
ATOM   9886  C CB  . GLN C 3 483 ? 182.542 198.926 144.757 1.00 103.37 ? 527 GLN C CB  1 
ATOM   9887  C CG  . GLN C 3 483 ? 183.130 197.757 145.529 1.00 103.37 ? 527 GLN C CG  1 
ATOM   9888  C CD  . GLN C 3 483 ? 183.002 196.444 144.785 1.00 103.37 ? 527 GLN C CD  1 
ATOM   9889  O OE1 . GLN C 3 483 ? 182.438 196.388 143.692 1.00 103.37 ? 527 GLN C OE1 1 
ATOM   9890  N NE2 . GLN C 3 483 ? 183.527 195.376 145.374 1.00 103.37 ? 527 GLN C NE2 1 
ATOM   9891  N N   . HIS C 3 484 ? 182.769 202.289 144.220 1.00 114.40 ? 528 HIS C N   1 
ATOM   9892  C CA  . HIS C 3 484 ? 182.304 203.419 143.431 1.00 114.40 ? 528 HIS C CA  1 
ATOM   9893  C C   . HIS C 3 484 ? 183.305 203.708 142.323 1.00 114.40 ? 528 HIS C C   1 
ATOM   9894  O O   . HIS C 3 484 ? 184.507 203.474 142.474 1.00 114.40 ? 528 HIS C O   1 
ATOM   9895  C CB  . HIS C 3 484 ? 182.102 204.668 144.300 1.00 114.40 ? 528 HIS C CB  1 
ATOM   9896  C CG  . HIS C 3 484 ? 181.375 205.776 143.605 1.00 114.40 ? 528 HIS C CG  1 
ATOM   9897  N ND1 . HIS C 3 484 ? 180.057 205.673 143.216 1.00 114.40 ? 528 HIS C ND1 1 
ATOM   9898  C CD2 . HIS C 3 484 ? 181.781 207.012 143.230 1.00 114.40 ? 528 HIS C CD2 1 
ATOM   9899  C CE1 . HIS C 3 484 ? 179.683 206.797 142.631 1.00 114.40 ? 528 HIS C CE1 1 
ATOM   9900  N NE2 . HIS C 3 484 ? 180.710 207.626 142.627 1.00 114.40 ? 528 HIS C NE2 1 
ATOM   9901  N N   . LEU C 3 485 ? 182.796 204.221 141.207 1.00 117.83 ? 529 LEU C N   1 
ATOM   9902  C CA  . LEU C 3 485 ? 183.610 204.541 140.045 1.00 117.83 ? 529 LEU C CA  1 
ATOM   9903  C C   . LEU C 3 485 ? 183.893 206.038 139.989 1.00 117.83 ? 529 LEU C C   1 
ATOM   9904  O O   . LEU C 3 485 ? 183.070 206.861 140.397 1.00 117.83 ? 529 LEU C O   1 
ATOM   9905  C CB  . LEU C 3 485 ? 182.918 204.091 138.756 1.00 117.83 ? 529 LEU C CB  1 
ATOM   9906  C CG  . LEU C 3 485 ? 183.734 204.166 137.464 1.00 117.83 ? 529 LEU C CG  1 
ATOM   9907  C CD1 . LEU C 3 485 ? 184.984 203.306 137.568 1.00 117.83 ? 529 LEU C CD1 1 
ATOM   9908  C CD2 . LEU C 3 485 ? 182.890 203.752 136.269 1.00 117.83 ? 529 LEU C CD2 1 
ATOM   9909  N N   . THR C 3 486 ? 185.071 206.381 139.476 1.00 119.12 ? 530 THR C N   1 
ATOM   9910  C CA  . THR C 3 486 ? 185.487 207.772 139.355 1.00 119.12 ? 530 THR C CA  1 
ATOM   9911  C C   . THR C 3 486 ? 184.843 208.396 138.117 1.00 119.12 ? 530 THR C C   1 
ATOM   9912  O O   . THR C 3 486 ? 183.935 207.830 137.502 1.00 119.12 ? 530 THR C O   1 
ATOM   9913  C CB  . THR C 3 486 ? 187.010 207.868 139.320 1.00 119.12 ? 530 THR C CB  1 
ATOM   9914  O OG1 . THR C 3 486 ? 187.533 206.862 138.444 1.00 119.12 ? 530 THR C OG1 1 
ATOM   9915  C CG2 . THR C 3 486 ? 187.588 207.669 140.713 1.00 119.12 ? 530 THR C CG2 1 
ATOM   9916  N N   . THR C 3 487 ? 185.314 209.580 137.735 1.00 132.93 ? 531 THR C N   1 
ATOM   9917  C CA  . THR C 3 487 ? 184.719 210.332 136.638 1.00 132.93 ? 531 THR C CA  1 
ATOM   9918  C C   . THR C 3 487 ? 185.119 209.716 135.297 1.00 132.93 ? 531 THR C C   1 
ATOM   9919  O O   . THR C 3 487 ? 185.756 208.661 135.230 1.00 132.93 ? 531 THR C O   1 
ATOM   9920  C CB  . THR C 3 487 ? 185.116 211.802 136.731 1.00 132.93 ? 531 THR C CB  1 
ATOM   9921  O OG1 . THR C 3 487 ? 186.534 211.905 136.908 1.00 132.93 ? 531 THR C OG1 1 
ATOM   9922  C CG2 . THR C 3 487 ? 184.408 212.466 137.903 1.00 132.93 ? 531 THR C CG2 1 
ATOM   9923  N N   . GLU C 3 488 ? 184.739 210.383 134.206 1.00 182.87 ? 532 GLU C N   1 
ATOM   9924  C CA  . GLU C 3 488 ? 184.888 209.835 132.862 1.00 182.87 ? 532 GLU C CA  1 
ATOM   9925  C C   . GLU C 3 488 ? 186.344 209.604 132.472 1.00 182.87 ? 532 GLU C C   1 
ATOM   9926  O O   . GLU C 3 488 ? 186.765 208.456 132.302 1.00 182.87 ? 532 GLU C O   1 
ATOM   9927  C CB  . GLU C 3 488 ? 184.224 210.761 131.840 1.00 182.87 ? 532 GLU C CB  1 
ATOM   9928  C CG  . GLU C 3 488 ? 182.734 210.974 132.060 1.00 182.87 ? 532 GLU C CG  1 
ATOM   9929  C CD  . GLU C 3 488 ? 182.442 212.111 133.020 1.00 182.87 ? 532 GLU C CD  1 
ATOM   9930  O OE1 . GLU C 3 488 ? 183.387 212.845 133.378 1.00 182.87 ? 532 GLU C OE1 1 
ATOM   9931  O OE2 . GLU C 3 488 ? 181.268 212.270 133.416 1.00 182.87 ? 532 GLU C OE2 1 
ATOM   9932  N N   . ALA C 3 489 ? 187.120 210.678 132.345 1.00 190.15 ? 533 ALA C N   1 
ATOM   9933  C CA  . ALA C 3 489 ? 188.486 210.579 131.842 1.00 190.15 ? 533 ALA C CA  1 
ATOM   9934  C C   . ALA C 3 489 ? 189.178 211.924 132.013 1.00 190.15 ? 533 ALA C C   1 
ATOM   9935  O O   . ALA C 3 489 ? 188.565 212.916 132.415 1.00 190.15 ? 533 ALA C O   1 
ATOM   9936  C CB  . ALA C 3 489 ? 188.514 210.149 130.372 1.00 190.15 ? 533 ALA C CB  1 
ATOM   9937  N N   . SER C 3 490 ? 190.474 211.937 131.701 1.00 196.19 ? 534 SER C N   1 
ATOM   9938  C CA  . SER C 3 490 ? 191.293 213.143 131.692 1.00 196.19 ? 534 SER C CA  1 
ATOM   9939  C C   . SER C 3 490 ? 192.448 212.963 130.713 1.00 196.19 ? 534 SER C C   1 
ATOM   9940  O O   . SER C 3 490 ? 193.410 212.245 131.015 1.00 196.19 ? 534 SER C O   1 
ATOM   9941  C CB  . SER C 3 490 ? 191.821 213.460 133.093 1.00 196.19 ? 534 SER C CB  1 
ATOM   9942  O OG  . SER C 3 490 ? 190.799 213.359 134.069 1.00 196.19 ? 534 SER C OG  1 
ATOM   9943  N N   . PRO C 3 491 ? 192.394 213.590 129.539 1.00 209.20 ? 535 PRO C N   1 
ATOM   9944  C CA  . PRO C 3 491 ? 193.473 213.408 128.560 1.00 209.20 ? 535 PRO C CA  1 
ATOM   9945  C C   . PRO C 3 491 ? 194.753 214.099 129.004 1.00 209.20 ? 535 PRO C C   1 
ATOM   9946  O O   . PRO C 3 491 ? 194.730 215.210 129.538 1.00 209.20 ? 535 PRO C O   1 
ATOM   9947  C CB  . PRO C 3 491 ? 192.906 214.043 127.286 1.00 209.20 ? 535 PRO C CB  1 
ATOM   9948  C CG  . PRO C 3 491 ? 191.928 215.056 127.781 1.00 209.20 ? 535 PRO C CG  1 
ATOM   9949  C CD  . PRO C 3 491 ? 191.336 214.488 129.043 1.00 209.20 ? 535 PRO C CD  1 
ATOM   9950  N N   . SER C 3 492 ? 195.879 213.424 128.778 1.00 210.10 ? 536 SER C N   1 
ATOM   9951  C CA  . SER C 3 492 ? 197.186 213.937 129.171 1.00 210.10 ? 536 SER C CA  1 
ATOM   9952  C C   . SER C 3 492 ? 198.106 214.178 127.986 1.00 210.10 ? 536 SER C C   1 
ATOM   9953  O O   . SER C 3 492 ? 198.664 215.275 127.855 1.00 210.10 ? 536 SER C O   1 
ATOM   9954  C CB  . SER C 3 492 ? 197.854 212.972 130.164 1.00 210.10 ? 536 SER C CB  1 
ATOM   9955  O OG  . SER C 3 492 ? 196.936 212.546 131.157 1.00 210.10 ? 536 SER C OG  1 
ATOM   9956  N N   . LYS C 3 493 ? 198.285 213.188 127.115 1.00 235.00 ? 537 LYS C N   1 
ATOM   9957  C CA  . LYS C 3 493 ? 199.203 213.301 125.989 1.00 235.00 ? 537 LYS C CA  1 
ATOM   9958  C C   . LYS C 3 493 ? 198.538 212.687 124.761 1.00 235.00 ? 537 LYS C C   1 
ATOM   9959  O O   . LYS C 3 493 ? 197.370 212.288 124.795 1.00 235.00 ? 537 LYS C O   1 
ATOM   9960  C CB  . LYS C 3 493 ? 200.547 212.637 126.320 1.00 235.00 ? 537 LYS C CB  1 
ATOM   9961  C CG  . LYS C 3 493 ? 201.757 213.337 125.718 1.00 235.00 ? 537 LYS C CG  1 
ATOM   9962  C CD  . LYS C 3 493 ? 203.052 212.667 126.147 1.00 235.00 ? 537 LYS C CD  1 
ATOM   9963  C CE  . LYS C 3 493 ? 204.259 213.343 125.517 1.00 235.00 ? 537 LYS C CE  1 
ATOM   9964  N NZ  . LYS C 3 493 ? 205.538 212.745 125.988 1.00 235.00 ? 537 LYS C NZ  1 
ATOM   9965  N N   . GLY C 3 494 ? 199.291 212.612 123.665 1.00 261.12 ? 538 GLY C N   1 
ATOM   9966  C CA  . GLY C 3 494 ? 198.789 212.070 122.426 1.00 261.12 ? 538 GLY C CA  1 
ATOM   9967  C C   . GLY C 3 494 ? 199.404 210.727 122.086 1.00 261.12 ? 538 GLY C C   1 
ATOM   9968  O O   . GLY C 3 494 ? 200.499 210.383 122.542 1.00 261.12 ? 538 GLY C O   1 
ATOM   9969  N N   . PRO C 3 495 ? 198.705 209.940 121.275 1.00 287.78 ? 539 PRO C N   1 
ATOM   9970  C CA  . PRO C 3 495 ? 199.210 208.615 120.906 1.00 287.78 ? 539 PRO C CA  1 
ATOM   9971  C C   . PRO C 3 495 ? 200.335 208.699 119.884 1.00 287.78 ? 539 PRO C C   1 
ATOM   9972  O O   . PRO C 3 495 ? 200.545 209.717 119.222 1.00 287.78 ? 539 PRO C O   1 
ATOM   9973  C CB  . PRO C 3 495 ? 197.982 207.914 120.307 1.00 287.78 ? 539 PRO C CB  1 
ATOM   9974  C CG  . PRO C 3 495 ? 196.806 208.816 120.602 1.00 287.78 ? 539 PRO C CG  1 
ATOM   9975  C CD  . PRO C 3 495 ? 197.368 210.192 120.718 1.00 287.78 ? 539 PRO C CD  1 
ATOM   9976  N N   . ASP C 3 496 ? 201.063 207.591 119.767 1.00 314.94 ? 540 ASP C N   1 
ATOM   9977  C CA  . ASP C 3 496 ? 202.122 207.474 118.775 1.00 314.94 ? 540 ASP C CA  1 
ATOM   9978  C C   . ASP C 3 496 ? 201.518 207.129 117.420 1.00 314.94 ? 540 ASP C C   1 
ATOM   9979  O O   . ASP C 3 496 ? 200.735 206.182 117.303 1.00 314.94 ? 540 ASP C O   1 
ATOM   9980  C CB  . ASP C 3 496 ? 203.134 206.409 119.197 1.00 314.94 ? 540 ASP C CB  1 
ATOM   9981  C CG  . ASP C 3 496 ? 204.400 206.445 118.365 1.00 314.94 ? 540 ASP C CG  1 
ATOM   9982  O OD1 . ASP C 3 496 ? 204.562 207.389 117.563 1.00 314.94 ? 540 ASP C OD1 1 
ATOM   9983  O OD2 . ASP C 3 496 ? 205.236 205.527 118.512 1.00 314.94 ? 540 ASP C OD2 1 
ATOM   9984  N N   . THR C 3 497 ? 201.884 207.897 116.397 1.00 312.92 ? 541 THR C N   1 
ATOM   9985  C CA  . THR C 3 497 ? 201.306 207.756 115.071 1.00 312.92 ? 541 THR C CA  1 
ATOM   9986  C C   . THR C 3 497 ? 202.397 207.499 114.038 1.00 312.92 ? 541 THR C C   1 
ATOM   9987  O O   . THR C 3 497 ? 203.574 207.799 114.254 1.00 312.92 ? 541 THR C O   1 
ATOM   9988  C CB  . THR C 3 497 ? 200.508 209.006 114.677 1.00 312.92 ? 541 THR C CB  1 
ATOM   9989  O OG1 . THR C 3 497 ? 201.324 210.170 114.849 1.00 312.92 ? 541 THR C OG1 1 
ATOM   9990  C CG2 . THR C 3 497 ? 199.266 209.136 115.544 1.00 312.92 ? 541 THR C CG2 1 
ATOM   9991  N N   . TRP C 3 498 ? 201.981 206.938 112.904 1.00 332.44 ? 542 TRP C N   1 
ATOM   9992  C CA  . TRP C 3 498 ? 202.879 206.683 111.787 1.00 332.44 ? 542 TRP C CA  1 
ATOM   9993  C C   . TRP C 3 498 ? 202.043 206.501 110.528 1.00 332.44 ? 542 TRP C C   1 
ATOM   9994  O O   . TRP C 3 498 ? 200.962 205.909 110.577 1.00 332.44 ? 542 TRP C O   1 
ATOM   9995  C CB  . TRP C 3 498 ? 203.753 205.448 112.033 1.00 332.44 ? 542 TRP C CB  1 
ATOM   9996  C CG  . TRP C 3 498 ? 204.582 205.051 110.848 1.00 332.44 ? 542 TRP C CG  1 
ATOM   9997  C CD1 . TRP C 3 498 ? 204.518 203.873 110.162 1.00 332.44 ? 542 TRP C CD1 1 
ATOM   9998  C CD2 . TRP C 3 498 ? 205.598 205.833 110.207 1.00 332.44 ? 542 TRP C CD2 1 
ATOM   9999  N NE1 . TRP C 3 498 ? 205.431 203.873 109.136 1.00 332.44 ? 542 TRP C NE1 1 
ATOM   10000 C CE2 . TRP C 3 498 ? 206.107 205.065 109.142 1.00 332.44 ? 542 TRP C CE2 1 
ATOM   10001 C CE3 . TRP C 3 498 ? 206.127 207.108 110.432 1.00 332.44 ? 542 TRP C CE3 1 
ATOM   10002 C CZ2 . TRP C 3 498 ? 207.118 205.528 108.303 1.00 332.44 ? 542 TRP C CZ2 1 
ATOM   10003 C CZ3 . TRP C 3 498 ? 207.131 207.567 109.598 1.00 332.44 ? 542 TRP C CZ3 1 
ATOM   10004 C CH2 . TRP C 3 498 ? 207.616 206.779 108.547 1.00 332.44 ? 542 TRP C CH2 1 
ATOM   10005 N N   . ARG C 3 499 ? 202.551 207.011 109.409 1.00 323.14 ? 543 ARG C N   1 
ATOM   10006 C CA  . ARG C 3 499 ? 201.849 206.965 108.137 1.00 323.14 ? 543 ARG C CA  1 
ATOM   10007 C C   . ARG C 3 499 ? 202.632 206.130 107.134 1.00 323.14 ? 543 ARG C C   1 
ATOM   10008 O O   . ARG C 3 499 ? 203.865 206.075 107.172 1.00 323.14 ? 543 ARG C O   1 
ATOM   10009 C CB  . ARG C 3 499 ? 201.623 208.375 107.574 1.00 323.14 ? 543 ARG C CB  1 
ATOM   10010 C CG  . ARG C 3 499 ? 202.884 209.224 107.492 1.00 323.14 ? 543 ARG C CG  1 
ATOM   10011 C CD  . ARG C 3 499 ? 203.459 209.230 106.084 1.00 323.14 ? 543 ARG C CD  1 
ATOM   10012 N NE  . ARG C 3 499 ? 204.765 209.881 106.026 1.00 323.14 ? 543 ARG C NE  1 
ATOM   10013 C CZ  . ARG C 3 499 ? 205.537 209.907 104.945 1.00 323.14 ? 543 ARG C CZ  1 
ATOM   10014 N NH1 . ARG C 3 499 ? 205.137 209.318 103.827 1.00 323.14 ? 543 ARG C NH1 1 
ATOM   10015 N NH2 . ARG C 3 499 ? 206.710 210.523 104.980 1.00 323.14 ? 543 ARG C NH2 1 
ATOM   10016 N N   . GLU C 3 500 ? 201.900 205.478 106.233 1.00 327.69 ? 544 GLU C N   1 
ATOM   10017 C CA  . GLU C 3 500 ? 202.493 204.693 105.162 1.00 327.69 ? 544 GLU C CA  1 
ATOM   10018 C C   . GLU C 3 500 ? 201.706 204.924 103.881 1.00 327.69 ? 544 GLU C C   1 
ATOM   10019 O O   . GLU C 3 500 ? 200.524 205.276 103.915 1.00 327.69 ? 544 GLU C O   1 
ATOM   10020 C CB  . GLU C 3 500 ? 202.521 203.195 105.496 1.00 327.69 ? 544 GLU C CB  1 
ATOM   10021 C CG  . GLU C 3 500 ? 203.394 202.835 106.686 1.00 327.69 ? 544 GLU C CG  1 
ATOM   10022 C CD  . GLU C 3 500 ? 203.617 201.342 106.814 1.00 327.69 ? 544 GLU C CD  1 
ATOM   10023 O OE1 . GLU C 3 500 ? 203.436 200.626 105.807 1.00 327.69 ? 544 GLU C OE1 1 
ATOM   10024 O OE2 . GLU C 3 500 ? 203.975 200.886 107.920 1.00 327.69 ? 544 GLU C OE2 1 
ATOM   10025 N N   . TRP C 3 501 ? 202.374 204.725 102.750 1.00 341.28 ? 545 TRP C N   1 
ATOM   10026 C CA  . TRP C 3 501 ? 201.758 204.885 101.443 1.00 341.28 ? 545 TRP C CA  1 
ATOM   10027 C C   . TRP C 3 501 ? 201.311 203.534 100.898 1.00 341.28 ? 545 TRP C C   1 
ATOM   10028 O O   . TRP C 3 501 ? 201.946 202.504 101.139 1.00 341.28 ? 545 TRP C O   1 
ATOM   10029 C CB  . TRP C 3 501 ? 202.723 205.551 100.460 1.00 341.28 ? 545 TRP C CB  1 
ATOM   10030 C CG  . TRP C 3 501 ? 202.791 207.039 100.608 1.00 341.28 ? 545 TRP C CG  1 
ATOM   10031 C CD1 . TRP C 3 501 ? 203.699 207.750 101.338 1.00 341.28 ? 545 TRP C CD1 1 
ATOM   10032 C CD2 . TRP C 3 501 ? 201.912 208.001 100.013 1.00 341.28 ? 545 TRP C CD2 1 
ATOM   10033 N NE1 . TRP C 3 501 ? 203.441 209.095 101.233 1.00 341.28 ? 545 TRP C NE1 1 
ATOM   10034 C CE2 . TRP C 3 501 ? 202.349 209.276 100.425 1.00 341.28 ? 545 TRP C CE2 1 
ATOM   10035 C CE3 . TRP C 3 501 ? 200.800 207.909 99.171  1.00 341.28 ? 545 TRP C CE3 1 
ATOM   10036 C CZ2 . TRP C 3 501 ? 201.712 210.449 100.024 1.00 341.28 ? 545 TRP C CZ2 1 
ATOM   10037 C CZ3 . TRP C 3 501 ? 200.169 209.074 98.774  1.00 341.28 ? 545 TRP C CZ3 1 
ATOM   10038 C CH2 . TRP C 3 501 ? 200.626 210.327 99.201  1.00 341.28 ? 545 TRP C CH2 1 
ATOM   10039 N N   . SER C 3 502 ? 200.206 203.551 100.157 1.00 376.99 ? 546 SER C N   1 
ATOM   10040 C CA  . SER C 3 502 ? 199.661 202.337 99.573  1.00 376.99 ? 546 SER C CA  1 
ATOM   10041 C C   . SER C 3 502 ? 200.439 201.962 98.312  1.00 376.99 ? 546 SER C C   1 
ATOM   10042 O O   . SER C 3 502 ? 201.356 202.665 97.878  1.00 376.99 ? 546 SER C O   1 
ATOM   10043 C CB  . SER C 3 502 ? 198.174 202.516 99.274  1.00 376.99 ? 546 SER C CB  1 
ATOM   10044 O OG  . SER C 3 502 ? 197.922 203.775 98.675  1.00 376.99 ? 546 SER C OG  1 
ATOM   10045 N N   . SER C 3 503 ? 200.064 200.830 97.713  1.00 395.74 ? 547 SER C N   1 
ATOM   10046 C CA  . SER C 3 503 ? 200.739 200.350 96.514  1.00 395.74 ? 547 SER C CA  1 
ATOM   10047 C C   . SER C 3 503 ? 200.366 201.144 95.269  1.00 395.74 ? 547 SER C C   1 
ATOM   10048 O O   . SER C 3 503 ? 201.096 201.086 94.273  1.00 395.74 ? 547 SER C O   1 
ATOM   10049 C CB  . SER C 3 503 ? 200.425 198.869 96.291  1.00 395.74 ? 547 SER C CB  1 
ATOM   10050 O OG  . SER C 3 503 ? 201.192 198.049 97.156  1.00 395.74 ? 547 SER C OG  1 
ATOM   10051 N N   . ASP C 3 504 ? 199.255 201.879 95.300  1.00 386.79 ? 548 ASP C N   1 
ATOM   10052 C CA  . ASP C 3 504 ? 198.811 202.659 94.154  1.00 386.79 ? 548 ASP C CA  1 
ATOM   10053 C C   . ASP C 3 504 ? 199.415 204.057 94.105  1.00 386.79 ? 548 ASP C C   1 
ATOM   10054 O O   . ASP C 3 504 ? 199.270 204.740 93.085  1.00 386.79 ? 548 ASP C O   1 
ATOM   10055 C CB  . ASP C 3 504 ? 197.280 202.760 94.147  1.00 386.79 ? 548 ASP C CB  1 
ATOM   10056 C CG  . ASP C 3 504 ? 196.726 203.419 95.400  1.00 386.79 ? 548 ASP C CG  1 
ATOM   10057 O OD1 . ASP C 3 504 ? 197.514 203.743 96.313  1.00 386.79 ? 548 ASP C OD1 1 
ATOM   10058 O OD2 . ASP C 3 504 ? 195.494 203.613 95.470  1.00 386.79 ? 548 ASP C OD2 1 
ATOM   10059 N N   . GLY C 3 505 ? 200.082 204.497 95.170  1.00 377.77 ? 549 GLY C N   1 
ATOM   10060 C CA  . GLY C 3 505 ? 200.651 205.829 95.199  1.00 377.77 ? 549 GLY C CA  1 
ATOM   10061 C C   . GLY C 3 505 ? 199.648 206.952 95.313  1.00 377.77 ? 549 GLY C C   1 
ATOM   10062 O O   . GLY C 3 505 ? 200.003 208.107 95.061  1.00 377.77 ? 549 GLY C O   1 
ATOM   10063 N N   . LYS C 3 506 ? 198.407 206.652 95.682  1.00 371.25 ? 550 LYS C N   1 
ATOM   10064 C CA  . LYS C 3 506 ? 197.355 207.651 95.814  1.00 371.25 ? 550 LYS C CA  1 
ATOM   10065 C C   . LYS C 3 506 ? 196.796 207.747 97.223  1.00 371.25 ? 550 LYS C C   1 
ATOM   10066 O O   . LYS C 3 506 ? 196.575 208.855 97.719  1.00 371.25 ? 550 LYS C O   1 
ATOM   10067 C CB  . LYS C 3 506 ? 196.213 207.340 94.831  1.00 371.25 ? 550 LYS C CB  1 
ATOM   10068 C CG  . LYS C 3 506 ? 195.050 208.323 94.864  1.00 371.25 ? 550 LYS C CG  1 
ATOM   10069 C CD  . LYS C 3 506 ? 195.525 209.766 94.797  1.00 371.25 ? 550 LYS C CD  1 
ATOM   10070 C CE  . LYS C 3 506 ? 194.380 210.732 95.058  1.00 371.25 ? 550 LYS C CE  1 
ATOM   10071 N NZ  . LYS C 3 506 ? 194.274 211.094 96.498  1.00 371.25 ? 550 LYS C NZ  1 
ATOM   10072 N N   . ASN C 3 507 ? 196.569 206.618 97.885  1.00 370.38 ? 551 ASN C N   1 
ATOM   10073 C CA  . ASN C 3 507 ? 196.011 206.611 99.228  1.00 370.38 ? 551 ASN C CA  1 
ATOM   10074 C C   . ASN C 3 507 ? 197.120 206.536 100.270 1.00 370.38 ? 551 ASN C C   1 
ATOM   10075 O O   . ASN C 3 507 ? 198.165 205.917 100.052 1.00 370.38 ? 551 ASN C O   1 
ATOM   10076 C CB  . ASN C 3 507 ? 195.046 205.437 99.405  1.00 370.38 ? 551 ASN C CB  1 
ATOM   10077 C CG  . ASN C 3 507 ? 193.880 205.774 100.313 1.00 370.38 ? 551 ASN C CG  1 
ATOM   10078 O OD1 . ASN C 3 507 ? 193.606 206.944 100.581 1.00 370.38 ? 551 ASN C OD1 1 
ATOM   10079 N ND2 . ASN C 3 507 ? 193.184 204.748 100.788 1.00 370.38 ? 551 ASN C ND2 1 
ATOM   10080 N N   . LEU C 3 508 ? 196.879 207.178 101.411 1.00 347.15 ? 552 LEU C N   1 
ATOM   10081 C CA  . LEU C 3 508 ? 197.830 207.225 102.517 1.00 347.15 ? 552 LEU C CA  1 
ATOM   10082 C C   . LEU C 3 508 ? 197.177 206.595 103.740 1.00 347.15 ? 552 LEU C C   1 
ATOM   10083 O O   . LEU C 3 508 ? 196.264 207.181 104.332 1.00 347.15 ? 552 LEU C O   1 
ATOM   10084 C CB  . LEU C 3 508 ? 198.264 208.661 102.805 1.00 347.15 ? 552 LEU C CB  1 
ATOM   10085 C CG  . LEU C 3 508 ? 199.264 208.861 103.947 1.00 347.15 ? 552 LEU C CG  1 
ATOM   10086 C CD1 . LEU C 3 508 ? 200.674 208.515 103.495 1.00 347.15 ? 552 LEU C CD1 1 
ATOM   10087 C CD2 . LEU C 3 508 ? 199.200 210.285 104.475 1.00 347.15 ? 552 LEU C CD2 1 
ATOM   10088 N N   . ILE C 3 509 ? 197.641 205.408 104.117 1.00 339.71 ? 553 ILE C N   1 
ATOM   10089 C CA  . ILE C 3 509 ? 197.117 204.721 105.291 1.00 339.71 ? 553 ILE C CA  1 
ATOM   10090 C C   . ILE C 3 509 ? 197.836 205.233 106.532 1.00 339.71 ? 553 ILE C C   1 
ATOM   10091 O O   . ILE C 3 509 ? 199.046 205.491 106.510 1.00 339.71 ? 553 ILE C O   1 
ATOM   10092 C CB  . ILE C 3 509 ? 197.259 203.194 105.135 1.00 339.71 ? 553 ILE C CB  1 
ATOM   10093 C CG1 . ILE C 3 509 ? 196.615 202.464 106.317 1.00 339.71 ? 553 ILE C CG1 1 
ATOM   10094 C CG2 . ILE C 3 509 ? 198.719 202.792 104.972 1.00 339.71 ? 553 ILE C CG2 1 
ATOM   10095 C CD1 . ILE C 3 509 ? 195.151 202.790 106.514 1.00 339.71 ? 553 ILE C CD1 1 
ATOM   10096 N N   . ILE C 3 510 ? 197.085 205.402 107.618 1.00 332.75 ? 554 ILE C N   1 
ATOM   10097 C CA  . ILE C 3 510 ? 197.607 205.936 108.868 1.00 332.75 ? 554 ILE C CA  1 
ATOM   10098 C C   . ILE C 3 510 ? 197.437 204.887 109.956 1.00 332.75 ? 554 ILE C C   1 
ATOM   10099 O O   . ILE C 3 510 ? 196.389 204.238 110.048 1.00 332.75 ? 554 ILE C O   1 
ATOM   10100 C CB  . ILE C 3 510 ? 196.902 207.250 109.264 1.00 332.75 ? 554 ILE C CB  1 
ATOM   10101 C CG1 . ILE C 3 510 ? 196.812 208.191 108.061 1.00 332.75 ? 554 ILE C CG1 1 
ATOM   10102 C CG2 . ILE C 3 510 ? 197.634 207.924 110.415 1.00 332.75 ? 554 ILE C CG2 1 
ATOM   10103 C CD1 . ILE C 3 510 ? 196.009 209.445 108.326 1.00 332.75 ? 554 ILE C CD1 1 
ATOM   10104 N N   . TYR C 3 511 ? 198.470 204.722 110.778 1.00 329.57 ? 555 TYR C N   1 
ATOM   10105 C CA  . TYR C 3 511 ? 198.448 203.790 111.894 1.00 329.57 ? 555 TYR C CA  1 
ATOM   10106 C C   . TYR C 3 511 ? 198.782 204.524 113.185 1.00 329.57 ? 555 TYR C C   1 
ATOM   10107 O O   . TYR C 3 511 ? 199.576 205.470 113.194 1.00 329.57 ? 555 TYR C O   1 
ATOM   10108 C CB  . TYR C 3 511 ? 199.439 202.639 111.681 1.00 329.57 ? 555 TYR C CB  1 
ATOM   10109 C CG  . TYR C 3 511 ? 199.141 201.784 110.470 1.00 329.57 ? 555 TYR C CG  1 
ATOM   10110 C CD1 . TYR C 3 511 ? 198.221 200.746 110.538 1.00 329.57 ? 555 TYR C CD1 1 
ATOM   10111 C CD2 . TYR C 3 511 ? 199.783 202.013 109.260 1.00 329.57 ? 555 TYR C CD2 1 
ATOM   10112 C CE1 . TYR C 3 511 ? 197.947 199.961 109.433 1.00 329.57 ? 555 TYR C CE1 1 
ATOM   10113 C CE2 . TYR C 3 511 ? 199.515 201.234 108.150 1.00 329.57 ? 555 TYR C CE2 1 
ATOM   10114 C CZ  . TYR C 3 511 ? 198.596 200.210 108.243 1.00 329.57 ? 555 TYR C CZ  1 
ATOM   10115 O OH  . TYR C 3 511 ? 198.326 199.431 107.140 1.00 329.57 ? 555 TYR C OH  1 
ATOM   10116 N N   . TRP C 3 512 ? 198.167 204.080 114.278 1.00 329.02 ? 556 TRP C N   1 
ATOM   10117 C CA  . TRP C 3 512 ? 198.407 204.675 115.584 1.00 329.02 ? 556 TRP C CA  1 
ATOM   10118 C C   . TRP C 3 512 ? 198.157 203.633 116.662 1.00 329.02 ? 556 TRP C C   1 
ATOM   10119 O O   . TRP C 3 512 ? 197.345 202.720 116.489 1.00 329.02 ? 556 TRP C O   1 
ATOM   10120 C CB  . TRP C 3 512 ? 197.525 205.908 115.817 1.00 329.02 ? 556 TRP C CB  1 
ATOM   10121 C CG  . TRP C 3 512 ? 196.057 205.636 115.701 1.00 329.02 ? 556 TRP C CG  1 
ATOM   10122 C CD1 . TRP C 3 512 ? 195.229 205.170 116.680 1.00 329.02 ? 556 TRP C CD1 1 
ATOM   10123 C CD2 . TRP C 3 512 ? 195.240 205.819 114.538 1.00 329.02 ? 556 TRP C CD2 1 
ATOM   10124 N NE1 . TRP C 3 512 ? 193.948 205.049 116.199 1.00 329.02 ? 556 TRP C NE1 1 
ATOM   10125 C CE2 . TRP C 3 512 ? 193.928 205.441 114.887 1.00 329.02 ? 556 TRP C CE2 1 
ATOM   10126 C CE3 . TRP C 3 512 ? 195.491 206.264 113.237 1.00 329.02 ? 556 TRP C CE3 1 
ATOM   10127 C CZ2 . TRP C 3 512 ? 192.871 205.495 113.982 1.00 329.02 ? 556 TRP C CZ2 1 
ATOM   10128 C CZ3 . TRP C 3 512 ? 194.440 206.317 112.340 1.00 329.02 ? 556 TRP C CZ3 1 
ATOM   10129 C CH2 . TRP C 3 512 ? 193.146 205.935 112.716 1.00 329.02 ? 556 TRP C CH2 1 
ATOM   10130 N N   . LYS C 3 513 ? 198.870 203.781 117.785 1.00 336.19 ? 557 LYS C N   1 
ATOM   10131 C CA  . LYS C 3 513 ? 198.760 202.882 118.920 1.00 336.19 ? 557 LYS C CA  1 
ATOM   10132 C C   . LYS C 3 513 ? 197.783 203.435 119.952 1.00 336.19 ? 557 LYS C C   1 
ATOM   10133 O O   . LYS C 3 513 ? 197.678 204.652 120.128 1.00 336.19 ? 557 LYS C O   1 
ATOM   10134 C CB  . LYS C 3 513 ? 200.126 202.674 119.581 1.00 336.19 ? 557 LYS C CB  1 
ATOM   10135 C CG  . LYS C 3 513 ? 201.234 202.292 118.614 1.00 336.19 ? 557 LYS C CG  1 
ATOM   10136 C CD  . LYS C 3 513 ? 202.581 202.241 119.316 1.00 336.19 ? 557 LYS C CD  1 
ATOM   10137 C CE  . LYS C 3 513 ? 203.708 201.991 118.328 1.00 336.19 ? 557 LYS C CE  1 
ATOM   10138 N NZ  . LYS C 3 513 ? 205.034 201.935 119.003 1.00 336.19 ? 557 LYS C NZ  1 
ATOM   10139 N N   . PRO C 3 514 ? 197.051 202.565 120.646 1.00 337.75 ? 558 PRO C N   1 
ATOM   10140 C CA  . PRO C 3 514 ? 196.133 203.046 121.684 1.00 337.75 ? 558 PRO C CA  1 
ATOM   10141 C C   . PRO C 3 514 ? 196.893 203.563 122.895 1.00 337.75 ? 558 PRO C C   1 
ATOM   10142 O O   . PRO C 3 514 ? 197.896 202.983 123.318 1.00 337.75 ? 558 PRO C O   1 
ATOM   10143 C CB  . PRO C 3 514 ? 195.304 201.804 122.029 1.00 337.75 ? 558 PRO C CB  1 
ATOM   10144 C CG  . PRO C 3 514 ? 196.195 200.658 121.684 1.00 337.75 ? 558 PRO C CG  1 
ATOM   10145 C CD  . PRO C 3 514 ? 196.998 201.100 120.492 1.00 337.75 ? 558 PRO C CD  1 
ATOM   10146 N N   . LEU C 3 515 ? 196.406 204.669 123.448 1.00 278.16 ? 559 LEU C N   1 
ATOM   10147 C CA  . LEU C 3 515 ? 197.053 205.261 124.608 1.00 278.16 ? 559 LEU C CA  1 
ATOM   10148 C C   . LEU C 3 515 ? 196.861 204.367 125.832 1.00 278.16 ? 559 LEU C C   1 
ATOM   10149 O O   . LEU C 3 515 ? 195.760 203.858 126.064 1.00 278.16 ? 559 LEU C O   1 
ATOM   10150 C CB  . LEU C 3 515 ? 196.492 206.654 124.885 1.00 278.16 ? 559 LEU C CB  1 
ATOM   10151 C CG  . LEU C 3 515 ? 197.156 207.816 124.145 1.00 278.16 ? 559 LEU C CG  1 
ATOM   10152 C CD1 . LEU C 3 515 ? 196.410 209.114 124.410 1.00 278.16 ? 559 LEU C CD1 1 
ATOM   10153 C CD2 . LEU C 3 515 ? 198.616 207.941 124.549 1.00 278.16 ? 559 LEU C CD2 1 
ATOM   10154 N N   . PRO C 3 516 ? 197.910 204.156 126.630 1.00 245.51 ? 560 PRO C N   1 
ATOM   10155 C CA  . PRO C 3 516 ? 197.774 203.306 127.822 1.00 245.51 ? 560 PRO C CA  1 
ATOM   10156 C C   . PRO C 3 516 ? 196.910 203.945 128.898 1.00 245.51 ? 560 PRO C C   1 
ATOM   10157 O O   . PRO C 3 516 ? 196.452 205.082 128.748 1.00 245.51 ? 560 PRO C O   1 
ATOM   10158 C CB  . PRO C 3 516 ? 199.223 203.128 128.298 1.00 245.51 ? 560 PRO C CB  1 
ATOM   10159 C CG  . PRO C 3 516 ? 200.081 203.545 127.136 1.00 245.51 ? 560 PRO C CG  1 
ATOM   10160 C CD  . PRO C 3 516 ? 199.298 204.595 126.420 1.00 245.51 ? 560 PRO C CD  1 
ATOM   10161 N N   . ILE C 3 517 ? 196.687 203.217 129.994 1.00 236.38 ? 561 ILE C N   1 
ATOM   10162 C CA  . ILE C 3 517 ? 195.838 203.731 131.065 1.00 236.38 ? 561 ILE C CA  1 
ATOM   10163 C C   . ILE C 3 517 ? 196.536 204.863 131.807 1.00 236.38 ? 561 ILE C C   1 
ATOM   10164 O O   . ILE C 3 517 ? 195.899 205.844 132.211 1.00 236.38 ? 561 ILE C O   1 
ATOM   10165 C CB  . ILE C 3 517 ? 195.434 202.590 132.016 1.00 236.38 ? 561 ILE C CB  1 
ATOM   10166 C CG1 . ILE C 3 517 ? 194.819 201.432 131.228 1.00 236.38 ? 561 ILE C CG1 1 
ATOM   10167 C CG2 . ILE C 3 517 ? 194.459 203.092 133.071 1.00 236.38 ? 561 ILE C CG2 1 
ATOM   10168 C CD1 . ILE C 3 517 ? 193.583 201.815 130.443 1.00 236.38 ? 561 ILE C CD1 1 
ATOM   10169 N N   . ASN C 3 518 ? 197.853 204.755 131.995 1.00 236.53 ? 562 ASN C N   1 
ATOM   10170 C CA  . ASN C 3 518 ? 198.588 205.792 132.710 1.00 236.53 ? 562 ASN C CA  1 
ATOM   10171 C C   . ASN C 3 518 ? 198.735 207.068 131.891 1.00 236.53 ? 562 ASN C C   1 
ATOM   10172 O O   . ASN C 3 518 ? 199.051 208.119 132.458 1.00 236.53 ? 562 ASN C O   1 
ATOM   10173 C CB  . ASN C 3 518 ? 199.969 205.276 133.120 1.00 236.53 ? 562 ASN C CB  1 
ATOM   10174 C CG  . ASN C 3 518 ? 200.886 205.057 131.933 1.00 236.53 ? 562 ASN C CG  1 
ATOM   10175 O OD1 . ASN C 3 518 ? 200.436 204.722 130.838 1.00 236.53 ? 562 ASN C OD1 1 
ATOM   10176 N ND2 . ASN C 3 518 ? 202.184 205.245 132.146 1.00 236.53 ? 562 ASN C ND2 1 
ATOM   10177 N N   . GLU C 3 519 ? 198.513 207.003 130.579 1.00 233.88 ? 563 GLU C N   1 
ATOM   10178 C CA  . GLU C 3 519 ? 198.611 208.167 129.708 1.00 233.88 ? 563 GLU C CA  1 
ATOM   10179 C C   . GLU C 3 519 ? 197.245 208.725 129.325 1.00 233.88 ? 563 GLU C C   1 
ATOM   10180 O O   . GLU C 3 519 ? 197.017 209.933 129.432 1.00 233.88 ? 563 GLU C O   1 
ATOM   10181 C CB  . GLU C 3 519 ? 199.405 207.813 128.444 1.00 233.88 ? 563 GLU C CB  1 
ATOM   10182 C CG  . GLU C 3 519 ? 200.796 207.268 128.721 1.00 233.88 ? 563 GLU C CG  1 
ATOM   10183 C CD  . GLU C 3 519 ? 201.602 207.057 127.455 1.00 233.88 ? 563 GLU C CD  1 
ATOM   10184 O OE1 . GLU C 3 519 ? 201.315 207.733 126.445 1.00 233.88 ? 563 GLU C OE1 1 
ATOM   10185 O OE2 . GLU C 3 519 ? 202.523 206.213 127.469 1.00 233.88 ? 563 GLU C OE2 1 
ATOM   10186 N N   . ALA C 3 520 ? 196.327 207.865 128.879 1.00 213.60 ? 564 ALA C N   1 
ATOM   10187 C CA  . ALA C 3 520 ? 194.995 208.335 128.514 1.00 213.60 ? 564 ALA C CA  1 
ATOM   10188 C C   . ALA C 3 520 ? 194.167 208.692 129.740 1.00 213.60 ? 564 ALA C C   1 
ATOM   10189 O O   . ALA C 3 520 ? 193.358 209.626 129.687 1.00 213.60 ? 564 ALA C O   1 
ATOM   10190 C CB  . ALA C 3 520 ? 194.273 207.279 127.678 1.00 213.60 ? 564 ALA C CB  1 
ATOM   10191 N N   . ASN C 3 521 ? 194.352 207.963 130.843 1.00 193.04 ? 565 ASN C N   1 
ATOM   10192 C CA  . ASN C 3 521 ? 193.600 208.175 132.081 1.00 193.04 ? 565 ASN C CA  1 
ATOM   10193 C C   . ASN C 3 521 ? 192.095 208.061 131.856 1.00 193.04 ? 565 ASN C C   1 
ATOM   10194 O O   . ASN C 3 521 ? 191.303 208.725 132.530 1.00 193.04 ? 565 ASN C O   1 
ATOM   10195 C CB  . ASN C 3 521 ? 193.945 209.524 132.720 1.00 193.04 ? 565 ASN C CB  1 
ATOM   10196 C CG  . ASN C 3 521 ? 195.435 209.706 132.929 1.00 193.04 ? 565 ASN C CG  1 
ATOM   10197 O OD1 . ASN C 3 521 ? 196.172 208.736 133.101 1.00 193.04 ? 565 ASN C OD1 1 
ATOM   10198 N ND2 . ASN C 3 521 ? 195.887 210.955 132.914 1.00 193.04 ? 565 ASN C ND2 1 
ATOM   10199 N N   . GLY C 3 522 ? 191.692 207.223 130.911 1.00 186.12 ? 566 GLY C N   1 
ATOM   10200 C CA  . GLY C 3 522 ? 190.282 207.047 130.624 1.00 186.12 ? 566 GLY C CA  1 
ATOM   10201 C C   . GLY C 3 522 ? 190.087 206.271 129.344 1.00 186.12 ? 566 GLY C C   1 
ATOM   10202 O O   . GLY C 3 522 ? 191.022 206.041 128.571 1.00 186.12 ? 566 GLY C O   1 
ATOM   10203 N N   . LYS C 3 523 ? 188.837 205.868 129.130 1.00 203.77 ? 567 LYS C N   1 
ATOM   10204 C CA  . LYS C 3 523 ? 188.465 205.113 127.941 1.00 203.77 ? 567 LYS C CA  1 
ATOM   10205 C C   . LYS C 3 523 ? 188.360 206.056 126.749 1.00 203.77 ? 567 LYS C C   1 
ATOM   10206 O O   . LYS C 3 523 ? 187.634 207.055 126.801 1.00 203.77 ? 567 LYS C O   1 
ATOM   10207 C CB  . LYS C 3 523 ? 187.145 204.380 128.168 1.00 203.77 ? 567 LYS C CB  1 
ATOM   10208 C CG  . LYS C 3 523 ? 186.648 203.605 126.960 1.00 203.77 ? 567 LYS C CG  1 
ATOM   10209 C CD  . LYS C 3 523 ? 185.316 202.932 127.249 1.00 203.77 ? 567 LYS C CD  1 
ATOM   10210 C CE  . LYS C 3 523 ? 184.812 202.163 126.039 1.00 203.77 ? 567 LYS C CE  1 
ATOM   10211 N NZ  . LYS C 3 523 ? 183.504 201.504 126.308 1.00 203.77 ? 567 LYS C NZ  1 
ATOM   10212 N N   . ILE C 3 524 ? 189.085 205.741 125.676 1.00 250.00 ? 568 ILE C N   1 
ATOM   10213 C CA  . ILE C 3 524 ? 189.047 206.566 124.475 1.00 250.00 ? 568 ILE C CA  1 
ATOM   10214 C C   . ILE C 3 524 ? 187.720 206.354 123.760 1.00 250.00 ? 568 ILE C C   1 
ATOM   10215 O O   . ILE C 3 524 ? 187.264 205.217 123.586 1.00 250.00 ? 568 ILE C O   1 
ATOM   10216 C CB  . ILE C 3 524 ? 190.235 206.236 123.559 1.00 250.00 ? 568 ILE C CB  1 
ATOM   10217 C CG1 . ILE C 3 524 ? 191.550 206.333 124.334 1.00 250.00 ? 568 ILE C CG1 1 
ATOM   10218 C CG2 . ILE C 3 524 ? 190.257 207.168 122.356 1.00 250.00 ? 568 ILE C CG2 1 
ATOM   10219 C CD1 . ILE C 3 524 ? 191.816 207.704 124.914 1.00 250.00 ? 568 ILE C CD1 1 
ATOM   10220 N N   . LEU C 3 525 ? 187.092 207.453 123.344 1.00 268.05 ? 569 LEU C N   1 
ATOM   10221 C CA  . LEU C 3 525 ? 185.820 207.383 122.635 1.00 268.05 ? 569 LEU C CA  1 
ATOM   10222 C C   . LEU C 3 525 ? 186.015 207.296 121.125 1.00 268.05 ? 569 LEU C C   1 
ATOM   10223 O O   . LEU C 3 525 ? 185.404 206.449 120.466 1.00 268.05 ? 569 LEU C O   1 
ATOM   10224 C CB  . LEU C 3 525 ? 184.954 208.597 122.987 1.00 268.05 ? 569 LEU C CB  1 
ATOM   10225 C CG  . LEU C 3 525 ? 184.529 208.740 124.448 1.00 268.05 ? 569 LEU C CG  1 
ATOM   10226 C CD1 . LEU C 3 525 ? 183.616 209.942 124.619 1.00 268.05 ? 569 LEU C CD1 1 
ATOM   10227 C CD2 . LEU C 3 525 ? 183.850 207.471 124.939 1.00 268.05 ? 569 LEU C CD2 1 
ATOM   10228 N N   . SER C 3 526 ? 186.858 208.160 120.568 1.00 298.98 ? 570 SER C N   1 
ATOM   10229 C CA  . SER C 3 526 ? 187.107 208.176 119.134 1.00 298.98 ? 570 SER C CA  1 
ATOM   10230 C C   . SER C 3 526 ? 188.439 208.866 118.880 1.00 298.98 ? 570 SER C C   1 
ATOM   10231 O O   . SER C 3 526 ? 189.072 209.398 119.795 1.00 298.98 ? 570 SER C O   1 
ATOM   10232 C CB  . SER C 3 526 ? 185.974 208.874 118.375 1.00 298.98 ? 570 SER C CB  1 
ATOM   10233 O OG  . SER C 3 526 ? 186.415 209.332 117.108 1.00 298.98 ? 570 SER C OG  1 
ATOM   10234 N N   . TYR C 3 527 ? 188.859 208.847 117.618 1.00 308.39 ? 571 TYR C N   1 
ATOM   10235 C CA  . TYR C 3 527 ? 190.094 209.485 117.184 1.00 308.39 ? 571 TYR C CA  1 
ATOM   10236 C C   . TYR C 3 527 ? 189.778 210.480 116.077 1.00 308.39 ? 571 TYR C C   1 
ATOM   10237 O O   . TYR C 3 527 ? 189.092 210.139 115.108 1.00 308.39 ? 571 TYR C O   1 
ATOM   10238 C CB  . TYR C 3 527 ? 191.110 208.449 116.697 1.00 308.39 ? 571 TYR C CB  1 
ATOM   10239 C CG  . TYR C 3 527 ? 191.737 207.641 117.810 1.00 308.39 ? 571 TYR C CG  1 
ATOM   10240 C CD1 . TYR C 3 527 ? 192.868 208.098 118.474 1.00 308.39 ? 571 TYR C CD1 1 
ATOM   10241 C CD2 . TYR C 3 527 ? 191.198 206.421 118.197 1.00 308.39 ? 571 TYR C CD2 1 
ATOM   10242 C CE1 . TYR C 3 527 ? 193.445 207.363 119.492 1.00 308.39 ? 571 TYR C CE1 1 
ATOM   10243 C CE2 . TYR C 3 527 ? 191.768 205.679 119.214 1.00 308.39 ? 571 TYR C CE2 1 
ATOM   10244 C CZ  . TYR C 3 527 ? 192.891 206.154 119.857 1.00 308.39 ? 571 TYR C CZ  1 
ATOM   10245 O OH  . TYR C 3 527 ? 193.462 205.418 120.870 1.00 308.39 ? 571 TYR C OH  1 
ATOM   10246 N N   . ASN C 3 528 ? 190.278 211.704 116.225 1.00 288.42 ? 572 ASN C N   1 
ATOM   10247 C CA  . ASN C 3 528 ? 190.053 212.773 115.258 1.00 288.42 ? 572 ASN C CA  1 
ATOM   10248 C C   . ASN C 3 528 ? 191.261 212.849 114.333 1.00 288.42 ? 572 ASN C C   1 
ATOM   10249 O O   . ASN C 3 528 ? 192.311 213.375 114.715 1.00 288.42 ? 572 ASN C O   1 
ATOM   10250 C CB  . ASN C 3 528 ? 189.818 214.104 115.967 1.00 288.42 ? 572 ASN C CB  1 
ATOM   10251 C CG  . ASN C 3 528 ? 188.862 213.982 117.137 1.00 288.42 ? 572 ASN C CG  1 
ATOM   10252 O OD1 . ASN C 3 528 ? 187.693 213.638 116.965 1.00 288.42 ? 572 ASN C OD1 1 
ATOM   10253 N ND2 . ASN C 3 528 ? 189.358 214.261 118.337 1.00 288.42 ? 572 ASN C ND2 1 
ATOM   10254 N N   . VAL C 3 529 ? 191.112 212.324 113.120 1.00 290.07 ? 573 VAL C N   1 
ATOM   10255 C CA  . VAL C 3 529 ? 192.176 212.339 112.125 1.00 290.07 ? 573 VAL C CA  1 
ATOM   10256 C C   . VAL C 3 529 ? 191.917 213.477 111.149 1.00 290.07 ? 573 VAL C C   1 
ATOM   10257 O O   . VAL C 3 529 ? 190.767 213.818 110.846 1.00 290.07 ? 573 VAL C O   1 
ATOM   10258 C CB  . VAL C 3 529 ? 192.291 210.990 111.383 1.00 290.07 ? 573 VAL C CB  1 
ATOM   10259 C CG1 . VAL C 3 529 ? 192.649 209.880 112.359 1.00 290.07 ? 573 VAL C CG1 1 
ATOM   10260 C CG2 . VAL C 3 529 ? 190.994 210.664 110.657 1.00 290.07 ? 573 VAL C CG2 1 
ATOM   10261 N N   . SER C 3 530 ? 193.003 214.077 110.664 1.00 301.29 ? 574 SER C N   1 
ATOM   10262 C CA  . SER C 3 530 ? 192.903 215.196 109.736 1.00 301.29 ? 574 SER C CA  1 
ATOM   10263 C C   . SER C 3 530 ? 194.236 215.374 109.028 1.00 301.29 ? 574 SER C C   1 
ATOM   10264 O O   . SER C 3 530 ? 195.265 215.568 109.681 1.00 301.29 ? 574 SER C O   1 
ATOM   10265 C CB  . SER C 3 530 ? 192.512 216.486 110.466 1.00 301.29 ? 574 SER C CB  1 
ATOM   10266 O OG  . SER C 3 530 ? 193.657 217.162 110.956 1.00 301.29 ? 574 SER C OG  1 
ATOM   10267 N N   . CYS C 3 531 ? 194.213 215.308 107.700 1.00 323.46 ? 575 CYS C N   1 
ATOM   10268 C CA  . CYS C 3 531 ? 195.381 215.580 106.866 1.00 323.46 ? 575 CYS C CA  1 
ATOM   10269 C C   . CYS C 3 531 ? 195.159 216.936 106.206 1.00 323.46 ? 575 CYS C C   1 
ATOM   10270 O O   . CYS C 3 531 ? 194.469 217.037 105.188 1.00 323.46 ? 575 CYS C O   1 
ATOM   10271 C CB  . CYS C 3 531 ? 195.593 214.476 105.836 1.00 323.46 ? 575 CYS C CB  1 
ATOM   10272 S SG  . CYS C 3 531 ? 195.361 212.803 106.477 1.00 323.46 ? 575 CYS C SG  1 
ATOM   10273 N N   . SER C 3 532 ? 195.746 217.977 106.791 1.00 323.24 ? 576 SER C N   1 
ATOM   10274 C CA  . SER C 3 532 ? 195.530 219.347 106.358 1.00 323.24 ? 576 SER C CA  1 
ATOM   10275 C C   . SER C 3 532 ? 196.830 219.956 105.850 1.00 323.24 ? 576 SER C C   1 
ATOM   10276 O O   . SER C 3 532 ? 197.923 219.581 106.283 1.00 323.24 ? 576 SER C O   1 
ATOM   10277 C CB  . SER C 3 532 ? 194.972 220.205 107.500 1.00 323.24 ? 576 SER C CB  1 
ATOM   10278 O OG  . SER C 3 532 ? 195.674 219.964 108.707 1.00 323.24 ? 576 SER C OG  1 
ATOM   10279 N N   . SER C 3 533 ? 196.696 220.898 104.921 1.00 314.50 ? 577 SER C N   1 
ATOM   10280 C CA  . SER C 3 533 ? 197.831 221.636 104.392 1.00 314.50 ? 577 SER C CA  1 
ATOM   10281 C C   . SER C 3 533 ? 197.959 222.966 105.133 1.00 314.50 ? 577 SER C C   1 
ATOM   10282 O O   . SER C 3 533 ? 197.280 223.215 106.133 1.00 314.50 ? 577 SER C O   1 
ATOM   10283 C CB  . SER C 3 533 ? 197.679 221.829 102.885 1.00 314.50 ? 577 SER C CB  1 
ATOM   10284 O OG  . SER C 3 533 ? 198.919 222.167 102.288 1.00 314.50 ? 577 SER C OG  1 
ATOM   10285 N N   . ASP C 3 534 ? 198.837 223.840 104.647 1.00 304.06 ? 578 ASP C N   1 
ATOM   10286 C CA  . ASP C 3 534 ? 199.053 225.140 105.270 1.00 304.06 ? 578 ASP C CA  1 
ATOM   10287 C C   . ASP C 3 534 ? 198.073 226.204 104.794 1.00 304.06 ? 578 ASP C C   1 
ATOM   10288 O O   . ASP C 3 534 ? 198.249 227.378 105.138 1.00 304.06 ? 578 ASP C O   1 
ATOM   10289 C CB  . ASP C 3 534 ? 200.486 225.614 105.012 1.00 304.06 ? 578 ASP C CB  1 
ATOM   10290 C CG  . ASP C 3 534 ? 201.525 224.665 105.574 1.00 304.06 ? 578 ASP C CG  1 
ATOM   10291 O OD1 . ASP C 3 534 ? 201.135 223.650 106.188 1.00 304.06 ? 578 ASP C OD1 1 
ATOM   10292 O OD2 . ASP C 3 534 ? 202.732 224.934 105.401 1.00 304.06 ? 578 ASP C OD2 1 
ATOM   10293 N N   . GLU C 3 535 ? 197.054 225.836 104.017 1.00 318.32 ? 579 GLU C N   1 
ATOM   10294 C CA  . GLU C 3 535 ? 196.123 226.825 103.487 1.00 318.32 ? 579 GLU C CA  1 
ATOM   10295 C C   . GLU C 3 535 ? 194.681 226.491 103.850 1.00 318.32 ? 579 GLU C C   1 
ATOM   10296 O O   . GLU C 3 535 ? 193.849 227.394 103.985 1.00 318.32 ? 579 GLU C O   1 
ATOM   10297 C CB  . GLU C 3 535 ? 196.258 226.953 101.963 1.00 318.32 ? 579 GLU C CB  1 
ATOM   10298 C CG  . GLU C 3 535 ? 197.674 227.191 101.430 1.00 318.32 ? 579 GLU C CG  1 
ATOM   10299 C CD  . GLU C 3 535 ? 198.569 225.968 101.517 1.00 318.32 ? 579 GLU C CD  1 
ATOM   10300 O OE1 . GLU C 3 535 ? 198.034 224.845 101.625 1.00 318.32 ? 579 GLU C OE1 1 
ATOM   10301 O OE2 . GLU C 3 535 ? 199.807 226.131 101.477 1.00 318.32 ? 579 GLU C OE2 1 
ATOM   10302 N N   . GLU C 3 536 ? 194.371 225.206 104.011 1.00 361.42 ? 580 GLU C N   1 
ATOM   10303 C CA  . GLU C 3 536 ? 192.998 224.799 104.276 1.00 361.42 ? 580 GLU C CA  1 
ATOM   10304 C C   . GLU C 3 536 ? 192.996 223.452 104.984 1.00 361.42 ? 580 GLU C C   1 
ATOM   10305 O O   . GLU C 3 536 ? 193.739 222.543 104.604 1.00 361.42 ? 580 GLU C O   1 
ATOM   10306 C CB  . GLU C 3 536 ? 192.186 224.721 102.977 1.00 361.42 ? 580 GLU C CB  1 
ATOM   10307 C CG  . GLU C 3 536 ? 190.844 224.023 103.117 1.00 361.42 ? 580 GLU C CG  1 
ATOM   10308 C CD  . GLU C 3 536 ? 190.030 224.068 101.840 1.00 361.42 ? 580 GLU C CD  1 
ATOM   10309 O OE1 . GLU C 3 536 ? 189.970 225.145 101.210 1.00 361.42 ? 580 GLU C OE1 1 
ATOM   10310 O OE2 . GLU C 3 536 ? 189.449 223.027 101.466 1.00 361.42 ? 580 GLU C OE2 1 
ATOM   10311 N N   . THR C 3 537 ? 192.156 223.334 106.009 1.00 379.86 ? 581 THR C N   1 
ATOM   10312 C CA  . THR C 3 537 ? 191.987 222.087 106.744 1.00 379.86 ? 581 THR C CA  1 
ATOM   10313 C C   . THR C 3 537 ? 190.934 221.235 106.044 1.00 379.86 ? 581 THR C C   1 
ATOM   10314 O O   . THR C 3 537 ? 189.796 221.678 105.855 1.00 379.86 ? 581 THR C O   1 
ATOM   10315 C CB  . THR C 3 537 ? 191.579 222.361 108.192 1.00 379.86 ? 581 THR C CB  1 
ATOM   10316 O OG1 . THR C 3 537 ? 190.575 223.383 108.223 1.00 379.86 ? 581 THR C OG1 1 
ATOM   10317 C CG2 . THR C 3 537 ? 192.781 222.815 109.006 1.00 379.86 ? 581 THR C CG2 1 
ATOM   10318 N N   . GLN C 3 538 ? 191.314 220.018 105.661 1.00 367.44 ? 582 GLN C N   1 
ATOM   10319 C CA  . GLN C 3 538 ? 190.433 219.118 104.936 1.00 367.44 ? 582 GLN C CA  1 
ATOM   10320 C C   . GLN C 3 538 ? 190.446 217.741 105.586 1.00 367.44 ? 582 GLN C C   1 
ATOM   10321 O O   . GLN C 3 538 ? 191.318 217.421 106.398 1.00 367.44 ? 582 GLN C O   1 
ATOM   10322 C CB  . GLN C 3 538 ? 190.839 218.998 103.459 1.00 367.44 ? 582 GLN C CB  1 
ATOM   10323 C CG  . GLN C 3 538 ? 190.895 220.321 102.715 1.00 367.44 ? 582 GLN C CG  1 
ATOM   10324 C CD  . GLN C 3 538 ? 191.409 220.171 101.297 1.00 367.44 ? 582 GLN C CD  1 
ATOM   10325 O OE1 . GLN C 3 538 ? 191.770 219.075 100.868 1.00 367.44 ? 582 GLN C OE1 1 
ATOM   10326 N NE2 . GLN C 3 538 ? 191.445 221.276 100.561 1.00 367.44 ? 582 GLN C NE2 1 
ATOM   10327 N N   . SER C 3 539 ? 189.465 216.926 105.200 1.00 332.99 ? 583 SER C N   1 
ATOM   10328 C CA  . SER C 3 539 ? 189.330 215.536 105.639 1.00 332.99 ? 583 SER C CA  1 
ATOM   10329 C C   . SER C 3 539 ? 189.367 215.425 107.164 1.00 332.99 ? 583 SER C C   1 
ATOM   10330 O O   . SER C 3 539 ? 190.265 214.824 107.756 1.00 332.99 ? 583 SER C O   1 
ATOM   10331 C CB  . SER C 3 539 ? 190.398 214.643 104.996 1.00 332.99 ? 583 SER C CB  1 
ATOM   10332 O OG  . SER C 3 539 ? 191.693 215.213 105.074 1.00 332.99 ? 583 SER C OG  1 
ATOM   10333 N N   . LEU C 3 540 ? 188.361 216.023 107.798 1.00 310.15 ? 584 LEU C N   1 
ATOM   10334 C CA  . LEU C 3 540 ? 188.202 215.968 109.251 1.00 310.15 ? 584 LEU C CA  1 
ATOM   10335 C C   . LEU C 3 540 ? 187.186 214.871 109.556 1.00 310.15 ? 584 LEU C C   1 
ATOM   10336 O O   . LEU C 3 540 ? 185.975 215.094 109.538 1.00 310.15 ? 584 LEU C O   1 
ATOM   10337 C CB  . LEU C 3 540 ? 187.767 217.320 109.805 1.00 310.15 ? 584 LEU C CB  1 
ATOM   10338 C CG  . LEU C 3 540 ? 187.483 217.398 111.308 1.00 310.15 ? 584 LEU C CG  1 
ATOM   10339 C CD1 . LEU C 3 540 ? 188.587 216.717 112.108 1.00 310.15 ? 584 LEU C CD1 1 
ATOM   10340 C CD2 . LEU C 3 540 ? 187.309 218.843 111.749 1.00 310.15 ? 584 LEU C CD2 1 
ATOM   10341 N N   . SER C 3 541 ? 187.691 213.672 109.835 1.00 311.95 ? 585 SER C N   1 
ATOM   10342 C CA  . SER C 3 541 ? 186.859 212.514 110.121 1.00 311.95 ? 585 SER C CA  1 
ATOM   10343 C C   . SER C 3 541 ? 187.152 211.994 111.522 1.00 311.95 ? 585 SER C C   1 
ATOM   10344 O O   . SER C 3 541 ? 188.238 212.209 112.068 1.00 311.95 ? 585 SER C O   1 
ATOM   10345 C CB  . SER C 3 541 ? 187.086 211.398 109.093 1.00 311.95 ? 585 SER C CB  1 
ATOM   10346 O OG  . SER C 3 541 ? 186.582 211.766 107.821 1.00 311.95 ? 585 SER C OG  1 
ATOM   10347 N N   . GLU C 3 542 ? 186.169 211.307 112.098 1.00 325.97 ? 586 GLU C N   1 
ATOM   10348 C CA  . GLU C 3 542 ? 186.273 210.742 113.438 1.00 325.97 ? 586 GLU C CA  1 
ATOM   10349 C C   . GLU C 3 542 ? 186.046 209.240 113.353 1.00 325.97 ? 586 GLU C C   1 
ATOM   10350 O O   . GLU C 3 542 ? 184.978 208.794 112.921 1.00 325.97 ? 586 GLU C O   1 
ATOM   10351 C CB  . GLU C 3 542 ? 185.261 211.388 114.388 1.00 325.97 ? 586 GLU C CB  1 
ATOM   10352 C CG  . GLU C 3 542 ? 185.391 212.899 114.510 1.00 325.97 ? 586 GLU C CG  1 
ATOM   10353 C CD  . GLU C 3 542 ? 184.616 213.641 113.438 1.00 325.97 ? 586 GLU C CD  1 
ATOM   10354 O OE1 . GLU C 3 542 ? 183.876 212.984 112.676 1.00 325.97 ? 586 GLU C OE1 1 
ATOM   10355 O OE2 . GLU C 3 542 ? 184.745 214.880 113.358 1.00 325.97 ? 586 GLU C OE2 1 
ATOM   10356 N N   . ILE C 3 543 ? 187.043 208.469 113.761 1.00 347.42 ? 587 ILE C N   1 
ATOM   10357 C CA  . ILE C 3 543 ? 186.988 207.009 113.741 1.00 347.42 ? 587 ILE C CA  1 
ATOM   10358 C C   . ILE C 3 543 ? 186.895 206.516 115.179 1.00 347.42 ? 587 ILE C C   1 
ATOM   10359 O O   . ILE C 3 543 ? 187.649 206.992 116.036 1.00 347.42 ? 587 ILE C O   1 
ATOM   10360 C CB  . ILE C 3 543 ? 188.211 206.399 113.024 1.00 347.42 ? 587 ILE C CB  1 
ATOM   10361 C CG1 . ILE C 3 543 ? 188.118 204.871 112.991 1.00 347.42 ? 587 ILE C CG1 1 
ATOM   10362 C CG2 . ILE C 3 543 ? 189.522 206.878 113.645 1.00 347.42 ? 587 ILE C CG2 1 
ATOM   10363 C CD1 . ILE C 3 543 ? 187.103 204.343 111.999 1.00 347.42 ? 587 ILE C CD1 1 
ATOM   10364 N N   . PRO C 3 544 ? 185.973 205.602 115.496 1.00 342.01 ? 588 PRO C N   1 
ATOM   10365 C CA  . PRO C 3 544 ? 185.871 205.108 116.875 1.00 342.01 ? 588 PRO C CA  1 
ATOM   10366 C C   . PRO C 3 544 ? 186.738 203.886 117.136 1.00 342.01 ? 588 PRO C C   1 
ATOM   10367 O O   . PRO C 3 544 ? 187.377 203.355 116.222 1.00 342.01 ? 588 PRO C O   1 
ATOM   10368 C CB  . PRO C 3 544 ? 184.382 204.776 117.008 1.00 342.01 ? 588 PRO C CB  1 
ATOM   10369 C CG  . PRO C 3 544 ? 183.989 204.353 115.630 1.00 342.01 ? 588 PRO C CG  1 
ATOM   10370 C CD  . PRO C 3 544 ? 184.841 205.153 114.665 1.00 342.01 ? 588 PRO C CD  1 
ATOM   10371 N N   . ASP C 3 545 ? 186.761 203.438 118.387 1.00 337.44 ? 589 ASP C N   1 
ATOM   10372 C CA  . ASP C 3 545 ? 187.496 202.248 118.777 1.00 337.44 ? 589 ASP C CA  1 
ATOM   10373 C C   . ASP C 3 545 ? 186.736 200.991 118.360 1.00 337.44 ? 589 ASP C C   1 
ATOM   10374 O O   . ASP C 3 545 ? 185.515 201.023 118.183 1.00 337.44 ? 589 ASP C O   1 
ATOM   10375 C CB  . ASP C 3 545 ? 187.726 202.253 120.287 1.00 337.44 ? 589 ASP C CB  1 
ATOM   10376 C CG  . ASP C 3 545 ? 188.936 203.075 120.688 1.00 337.44 ? 589 ASP C CG  1 
ATOM   10377 O OD1 . ASP C 3 545 ? 189.897 203.146 119.894 1.00 337.44 ? 589 ASP C OD1 1 
ATOM   10378 O OD2 . ASP C 3 545 ? 188.926 203.647 121.798 1.00 337.44 ? 589 ASP C OD2 1 
ATOM   10379 N N   . PRO C 3 546 ? 187.437 199.855 118.192 1.00 348.44 ? 590 PRO C N   1 
ATOM   10380 C CA  . PRO C 3 546 ? 188.882 199.664 118.347 1.00 348.44 ? 590 PRO C CA  1 
ATOM   10381 C C   . PRO C 3 546 ? 189.660 199.830 117.046 1.00 348.44 ? 590 PRO C C   1 
ATOM   10382 O O   . PRO C 3 546 ? 190.778 199.326 116.935 1.00 348.44 ? 590 PRO C O   1 
ATOM   10383 C CB  . PRO C 3 546 ? 188.977 198.226 118.848 1.00 348.44 ? 590 PRO C CB  1 
ATOM   10384 C CG  . PRO C 3 546 ? 187.843 197.539 118.153 1.00 348.44 ? 590 PRO C CG  1 
ATOM   10385 C CD  . PRO C 3 546 ? 186.751 198.574 117.946 1.00 348.44 ? 590 PRO C CD  1 
ATOM   10386 N N   . GLN C 3 547 ? 189.074 200.525 116.075 1.00 340.16 ? 591 GLN C N   1 
ATOM   10387 C CA  . GLN C 3 547 ? 189.737 200.731 114.793 1.00 340.16 ? 591 GLN C CA  1 
ATOM   10388 C C   . GLN C 3 547 ? 190.914 201.682 114.968 1.00 340.16 ? 591 GLN C C   1 
ATOM   10389 O O   . GLN C 3 547 ? 190.730 202.858 115.299 1.00 340.16 ? 591 GLN C O   1 
ATOM   10390 C CB  . GLN C 3 547 ? 188.748 201.279 113.767 1.00 340.16 ? 591 GLN C CB  1 
ATOM   10391 C CG  . GLN C 3 547 ? 189.334 201.451 112.374 1.00 340.16 ? 591 GLN C CG  1 
ATOM   10392 C CD  . GLN C 3 547 ? 189.341 200.162 111.576 1.00 340.16 ? 591 GLN C CD  1 
ATOM   10393 O OE1 . GLN C 3 547 ? 188.967 199.102 112.080 1.00 340.16 ? 591 GLN C OE1 1 
ATOM   10394 N NE2 . GLN C 3 547 ? 189.767 200.246 110.321 1.00 340.16 ? 591 GLN C NE2 1 
ATOM   10395 N N   . HIS C 3 548 ? 192.126 201.173 114.744 1.00 332.70 ? 592 HIS C N   1 
ATOM   10396 C CA  . HIS C 3 548 ? 193.348 201.949 114.909 1.00 332.70 ? 592 HIS C CA  1 
ATOM   10397 C C   . HIS C 3 548 ? 193.996 202.300 113.574 1.00 332.70 ? 592 HIS C C   1 
ATOM   10398 O O   . HIS C 3 548 ? 195.195 202.593 113.528 1.00 332.70 ? 592 HIS C O   1 
ATOM   10399 C CB  . HIS C 3 548 ? 194.336 201.194 115.799 1.00 332.70 ? 592 HIS C CB  1 
ATOM   10400 C CG  . HIS C 3 548 ? 193.845 200.976 117.196 1.00 332.70 ? 592 HIS C CG  1 
ATOM   10401 N ND1 . HIS C 3 548 ? 194.425 200.070 118.057 1.00 332.70 ? 592 HIS C ND1 1 
ATOM   10402 C CD2 . HIS C 3 548 ? 192.826 201.547 117.882 1.00 332.70 ? 592 HIS C CD2 1 
ATOM   10403 C CE1 . HIS C 3 548 ? 193.786 200.092 119.213 1.00 332.70 ? 592 HIS C CE1 1 
ATOM   10404 N NE2 . HIS C 3 548 ? 192.811 200.980 119.133 1.00 332.70 ? 592 HIS C NE2 1 
ATOM   10405 N N   . LYS C 3 549 ? 193.226 202.278 112.489 1.00 331.80 ? 593 LYS C N   1 
ATOM   10406 C CA  . LYS C 3 549 ? 193.741 202.632 111.175 1.00 331.80 ? 593 LYS C CA  1 
ATOM   10407 C C   . LYS C 3 549 ? 192.650 203.344 110.391 1.00 331.80 ? 593 LYS C C   1 
ATOM   10408 O O   . LYS C 3 549 ? 191.460 203.072 110.567 1.00 331.80 ? 593 LYS C O   1 
ATOM   10409 C CB  . LYS C 3 549 ? 194.235 201.398 110.409 1.00 331.80 ? 593 LYS C CB  1 
ATOM   10410 C CG  . LYS C 3 549 ? 193.160 200.357 110.144 1.00 331.80 ? 593 LYS C CG  1 
ATOM   10411 C CD  . LYS C 3 549 ? 193.697 199.210 109.303 1.00 331.80 ? 593 LYS C CD  1 
ATOM   10412 C CE  . LYS C 3 549 ? 192.609 198.193 109.001 1.00 331.80 ? 593 LYS C CE  1 
ATOM   10413 N NZ  . LYS C 3 549 ? 193.113 197.073 108.160 1.00 331.80 ? 593 LYS C NZ  1 
ATOM   10414 N N   . ALA C 3 550 ? 193.069 204.264 109.526 1.00 340.40 ? 594 ALA C N   1 
ATOM   10415 C CA  . ALA C 3 550 ? 192.131 205.032 108.720 1.00 340.40 ? 594 ALA C CA  1 
ATOM   10416 C C   . ALA C 3 550 ? 192.835 205.501 107.456 1.00 340.40 ? 594 ALA C C   1 
ATOM   10417 O O   . ALA C 3 550 ? 194.046 205.736 107.455 1.00 340.40 ? 594 ALA C O   1 
ATOM   10418 C CB  . ALA C 3 550 ? 191.568 206.228 109.495 1.00 340.40 ? 594 ALA C CB  1 
ATOM   10419 N N   . GLU C 3 551 ? 192.060 205.636 106.385 1.00 355.63 ? 595 GLU C N   1 
ATOM   10420 C CA  . GLU C 3 551 ? 192.568 206.064 105.090 1.00 355.63 ? 595 GLU C CA  1 
ATOM   10421 C C   . GLU C 3 551 ? 191.976 207.418 104.721 1.00 355.63 ? 595 GLU C C   1 
ATOM   10422 O O   . GLU C 3 551 ? 190.806 207.695 105.005 1.00 355.63 ? 595 GLU C O   1 
ATOM   10423 C CB  . GLU C 3 551 ? 192.262 205.014 104.010 1.00 355.63 ? 595 GLU C CB  1 
ATOM   10424 C CG  . GLU C 3 551 ? 190.786 204.833 103.641 1.00 355.63 ? 595 GLU C CG  1 
ATOM   10425 C CD  . GLU C 3 551 ? 190.284 205.853 102.635 1.00 355.63 ? 595 GLU C CD  1 
ATOM   10426 O OE1 . GLU C 3 551 ? 191.119 206.459 101.932 1.00 355.63 ? 595 GLU C OE1 1 
ATOM   10427 O OE2 . GLU C 3 551 ? 189.053 206.046 102.546 1.00 355.63 ? 595 GLU C OE2 1 
ATOM   10428 N N   . ILE C 3 552 ? 192.798 208.265 104.104 1.00 355.97 ? 596 ILE C N   1 
ATOM   10429 C CA  . ILE C 3 552 ? 192.385 209.592 103.659 1.00 355.97 ? 596 ILE C CA  1 
ATOM   10430 C C   . ILE C 3 552 ? 193.066 209.872 102.327 1.00 355.97 ? 596 ILE C C   1 
ATOM   10431 O O   . ILE C 3 552 ? 194.298 209.826 102.235 1.00 355.97 ? 596 ILE C O   1 
ATOM   10432 C CB  . ILE C 3 552 ? 192.733 210.689 104.682 1.00 355.97 ? 596 ILE C CB  1 
ATOM   10433 C CG1 . ILE C 3 552 ? 191.736 210.674 105.844 1.00 355.97 ? 596 ILE C CG1 1 
ATOM   10434 C CG2 . ILE C 3 552 ? 192.759 212.056 104.015 1.00 355.97 ? 596 ILE C CG2 1 
ATOM   10435 C CD1 . ILE C 3 552 ? 191.926 211.799 106.836 1.00 355.97 ? 596 ILE C CD1 1 
ATOM   10436 N N   . ARG C 3 553 ? 192.272 210.153 101.297 1.00 361.65 ? 597 ARG C N   1 
ATOM   10437 C CA  . ARG C 3 553 ? 192.811 210.436 99.974  1.00 361.65 ? 597 ARG C CA  1 
ATOM   10438 C C   . ARG C 3 553 ? 193.400 211.840 99.937  1.00 361.65 ? 597 ARG C C   1 
ATOM   10439 O O   . ARG C 3 553 ? 192.743 212.810 100.326 1.00 361.65 ? 597 ARG C O   1 
ATOM   10440 C CB  . ARG C 3 553 ? 191.722 210.287 98.913  1.00 361.65 ? 597 ARG C CB  1 
ATOM   10441 C CG  . ARG C 3 553 ? 191.077 208.910 98.877  1.00 361.65 ? 597 ARG C CG  1 
ATOM   10442 C CD  . ARG C 3 553 ? 189.662 208.977 98.327  1.00 361.65 ? 597 ARG C CD  1 
ATOM   10443 N NE  . ARG C 3 553 ? 188.827 209.908 99.081  1.00 361.65 ? 597 ARG C NE  1 
ATOM   10444 C CZ  . ARG C 3 553 ? 188.195 209.601 100.209 1.00 361.65 ? 597 ARG C CZ  1 
ATOM   10445 N NH1 . ARG C 3 553 ? 188.300 208.381 100.720 1.00 361.65 ? 597 ARG C NH1 1 
ATOM   10446 N NH2 . ARG C 3 553 ? 187.457 210.512 100.826 1.00 361.65 ? 597 ARG C NH2 1 
ATOM   10447 N N   . LEU C 3 554 ? 194.640 211.946 99.466  1.00 357.78 ? 598 LEU C N   1 
ATOM   10448 C CA  . LEU C 3 554 ? 195.348 213.214 99.383  1.00 357.78 ? 598 LEU C CA  1 
ATOM   10449 C C   . LEU C 3 554 ? 195.868 213.424 97.968  1.00 357.78 ? 598 LEU C C   1 
ATOM   10450 O O   . LEU C 3 554 ? 196.296 212.474 97.305  1.00 357.78 ? 598 LEU C O   1 
ATOM   10451 C CB  . LEU C 3 554 ? 196.512 213.266 100.380 1.00 357.78 ? 598 LEU C CB  1 
ATOM   10452 C CG  . LEU C 3 554 ? 196.135 213.254 101.862 1.00 357.78 ? 598 LEU C CG  1 
ATOM   10453 C CD1 . LEU C 3 554 ? 197.375 213.391 102.730 1.00 357.78 ? 598 LEU C CD1 1 
ATOM   10454 C CD2 . LEU C 3 554 ? 195.135 214.358 102.167 1.00 357.78 ? 598 LEU C CD2 1 
ATOM   10455 N N   . ASP C 3 555 ? 195.826 214.675 97.511  1.00 361.57 ? 599 ASP C N   1 
ATOM   10456 C CA  . ASP C 3 555 ? 196.307 215.018 96.180  1.00 361.57 ? 599 ASP C CA  1 
ATOM   10457 C C   . ASP C 3 555 ? 197.744 215.518 96.176  1.00 361.57 ? 599 ASP C C   1 
ATOM   10458 O O   . ASP C 3 555 ? 198.419 215.413 95.145  1.00 361.57 ? 599 ASP C O   1 
ATOM   10459 C CB  . ASP C 3 555 ? 195.402 216.081 95.550  1.00 361.57 ? 599 ASP C CB  1 
ATOM   10460 C CG  . ASP C 3 555 ? 193.942 215.675 95.546  1.00 361.57 ? 599 ASP C CG  1 
ATOM   10461 O OD1 . ASP C 3 555 ? 193.664 214.459 95.490  1.00 361.57 ? 599 ASP C OD1 1 
ATOM   10462 O OD2 . ASP C 3 555 ? 193.073 216.571 95.600  1.00 361.57 ? 599 ASP C OD2 1 
ATOM   10463 N N   . LYS C 3 556 ? 198.227 216.051 97.296  1.00 346.36 ? 600 LYS C N   1 
ATOM   10464 C CA  . LYS C 3 556 ? 199.578 216.580 97.397  1.00 346.36 ? 600 LYS C CA  1 
ATOM   10465 C C   . LYS C 3 556 ? 200.233 216.016 98.653  1.00 346.36 ? 600 LYS C C   1 
ATOM   10466 O O   . LYS C 3 556 ? 199.556 215.526 99.560  1.00 346.36 ? 600 LYS C O   1 
ATOM   10467 C CB  . LYS C 3 556 ? 199.565 218.119 97.413  1.00 346.36 ? 600 LYS C CB  1 
ATOM   10468 C CG  . LYS C 3 556 ? 200.928 218.780 97.264  1.00 346.36 ? 600 LYS C CG  1 
ATOM   10469 C CD  . LYS C 3 556 ? 200.811 220.133 96.573  1.00 346.36 ? 600 LYS C CD  1 
ATOM   10470 C CE  . LYS C 3 556 ? 199.927 221.091 97.360  1.00 346.36 ? 600 LYS C CE  1 
ATOM   10471 N NZ  . LYS C 3 556 ? 200.262 222.513 97.071  1.00 346.36 ? 600 LYS C NZ  1 
ATOM   10472 N N   . ASN C 3 557 ? 201.563 216.077 98.696  1.00 340.19 ? 601 ASN C N   1 
ATOM   10473 C CA  . ASN C 3 557 ? 202.335 215.456 99.765  1.00 340.19 ? 601 ASN C CA  1 
ATOM   10474 C C   . ASN C 3 557 ? 202.718 216.420 100.880 1.00 340.19 ? 601 ASN C C   1 
ATOM   10475 O O   . ASN C 3 557 ? 203.440 216.023 101.800 1.00 340.19 ? 601 ASN C O   1 
ATOM   10476 C CB  . ASN C 3 557 ? 203.601 214.811 99.192  1.00 340.19 ? 601 ASN C CB  1 
ATOM   10477 C CG  . ASN C 3 557 ? 203.294 213.758 98.148  1.00 340.19 ? 601 ASN C CG  1 
ATOM   10478 O OD1 . ASN C 3 557 ? 202.264 213.088 98.209  1.00 340.19 ? 601 ASN C OD1 1 
ATOM   10479 N ND2 . ASN C 3 557 ? 204.191 213.605 97.182  1.00 340.19 ? 601 ASN C ND2 1 
ATOM   10480 N N   . ASP C 3 558 ? 202.256 217.669 100.829 1.00 338.73 ? 602 ASP C N   1 
ATOM   10481 C CA  . ASP C 3 558 ? 202.592 218.660 101.841 1.00 338.73 ? 602 ASP C CA  1 
ATOM   10482 C C   . ASP C 3 558 ? 201.550 218.750 102.951 1.00 338.73 ? 602 ASP C C   1 
ATOM   10483 O O   . ASP C 3 558 ? 201.533 219.738 103.695 1.00 338.73 ? 602 ASP C O   1 
ATOM   10484 C CB  . ASP C 3 558 ? 202.785 220.032 101.190 1.00 338.73 ? 602 ASP C CB  1 
ATOM   10485 C CG  . ASP C 3 558 ? 201.546 220.512 100.458 1.00 338.73 ? 602 ASP C CG  1 
ATOM   10486 O OD1 . ASP C 3 558 ? 200.610 219.706 100.273 1.00 338.73 ? 602 ASP C OD1 1 
ATOM   10487 O OD2 . ASP C 3 558 ? 201.508 221.698 100.071 1.00 338.73 ? 602 ASP C OD2 1 
ATOM   10488 N N   . TYR C 3 559 ? 200.689 217.745 103.084 1.00 343.15 ? 603 TYR C N   1 
ATOM   10489 C CA  . TYR C 3 559 ? 199.652 217.749 104.106 1.00 343.15 ? 603 TYR C CA  1 
ATOM   10490 C C   . TYR C 3 559 ? 200.190 217.168 105.406 1.00 343.15 ? 603 TYR C C   1 
ATOM   10491 O O   . TYR C 3 559 ? 200.892 216.152 105.404 1.00 343.15 ? 603 TYR C O   1 
ATOM   10492 C CB  . TYR C 3 559 ? 198.434 216.948 103.641 1.00 343.15 ? 603 TYR C CB  1 
ATOM   10493 C CG  . TYR C 3 559 ? 197.617 217.633 102.570 1.00 343.15 ? 603 TYR C CG  1 
ATOM   10494 C CD1 . TYR C 3 559 ? 196.456 218.324 102.891 1.00 343.15 ? 603 TYR C CD1 1 
ATOM   10495 C CD2 . TYR C 3 559 ? 198.004 217.587 101.239 1.00 343.15 ? 603 TYR C CD2 1 
ATOM   10496 C CE1 . TYR C 3 559 ? 195.705 218.950 101.915 1.00 343.15 ? 603 TYR C CE1 1 
ATOM   10497 C CE2 . TYR C 3 559 ? 197.260 218.209 100.255 1.00 343.15 ? 603 TYR C CE2 1 
ATOM   10498 C CZ  . TYR C 3 559 ? 196.112 218.890 100.598 1.00 343.15 ? 603 TYR C CZ  1 
ATOM   10499 O OH  . TYR C 3 559 ? 195.370 219.510 99.620  1.00 343.15 ? 603 TYR C OH  1 
ATOM   10500 N N   . ILE C 3 560 ? 199.853 217.818 106.518 1.00 323.89 ? 604 ILE C N   1 
ATOM   10501 C CA  . ILE C 3 560 ? 200.258 217.373 107.847 1.00 323.89 ? 604 ILE C CA  1 
ATOM   10502 C C   . ILE C 3 560 ? 199.109 216.600 108.473 1.00 323.89 ? 604 ILE C C   1 
ATOM   10503 O O   . ILE C 3 560 ? 197.933 216.907 108.237 1.00 323.89 ? 604 ILE C O   1 
ATOM   10504 C CB  . ILE C 3 560 ? 200.684 218.561 108.733 1.00 323.89 ? 604 ILE C CB  1 
ATOM   10505 C CG1 . ILE C 3 560 ? 199.482 219.438 109.093 1.00 323.89 ? 604 ILE C CG1 1 
ATOM   10506 C CG2 . ILE C 3 560 ? 201.755 219.387 108.038 1.00 323.89 ? 604 ILE C CG2 1 
ATOM   10507 C CD1 . ILE C 3 560 ? 199.651 220.202 110.388 1.00 323.89 ? 604 ILE C CD1 1 
ATOM   10508 N N   . ILE C 3 561 ? 199.445 215.585 109.264 1.00 315.18 ? 605 ILE C N   1 
ATOM   10509 C CA  . ILE C 3 561 ? 198.465 214.710 109.895 1.00 315.18 ? 605 ILE C CA  1 
ATOM   10510 C C   . ILE C 3 561 ? 198.384 215.063 111.373 1.00 315.18 ? 605 ILE C C   1 
ATOM   10511 O O   . ILE C 3 561 ? 199.414 215.184 112.047 1.00 315.18 ? 605 ILE C O   1 
ATOM   10512 C CB  . ILE C 3 561 ? 198.823 213.227 109.701 1.00 315.18 ? 605 ILE C CB  1 
ATOM   10513 C CG1 . ILE C 3 561 ? 199.301 212.980 108.268 1.00 315.18 ? 605 ILE C CG1 1 
ATOM   10514 C CG2 . ILE C 3 561 ? 197.630 212.345 110.029 1.00 315.18 ? 605 ILE C CG2 1 
ATOM   10515 C CD1 . ILE C 3 561 ? 200.021 211.664 108.083 1.00 315.18 ? 605 ILE C CD1 1 
ATOM   10516 N N   . SER C 3 562 ? 197.159 215.227 111.874 1.00 285.49 ? 606 SER C N   1 
ATOM   10517 C CA  . SER C 3 562 ? 196.902 215.569 113.273 1.00 285.49 ? 606 SER C CA  1 
ATOM   10518 C C   . SER C 3 562 ? 195.884 214.572 113.819 1.00 285.49 ? 606 SER C C   1 
ATOM   10519 O O   . SER C 3 562 ? 194.674 214.796 113.734 1.00 285.49 ? 606 SER C O   1 
ATOM   10520 C CB  . SER C 3 562 ? 196.411 217.008 113.403 1.00 285.49 ? 606 SER C CB  1 
ATOM   10521 O OG  . SER C 3 562 ? 195.701 217.197 114.615 1.00 285.49 ? 606 SER C OG  1 
ATOM   10522 N N   . VAL C 3 563 ? 196.378 213.473 114.378 1.00 274.51 ? 607 VAL C N   1 
ATOM   10523 C CA  . VAL C 3 563 ? 195.526 212.452 114.976 1.00 274.51 ? 607 VAL C CA  1 
ATOM   10524 C C   . VAL C 3 563 ? 195.279 212.828 116.431 1.00 274.51 ? 607 VAL C C   1 
ATOM   10525 O O   . VAL C 3 563 ? 196.216 212.883 117.235 1.00 274.51 ? 607 VAL C O   1 
ATOM   10526 C CB  . VAL C 3 563 ? 196.161 211.058 114.864 1.00 274.51 ? 607 VAL C CB  1 
ATOM   10527 C CG1 . VAL C 3 563 ? 195.138 209.981 115.188 1.00 274.51 ? 607 VAL C CG1 1 
ATOM   10528 C CG2 . VAL C 3 563 ? 196.736 210.852 113.471 1.00 274.51 ? 607 VAL C CG2 1 
ATOM   10529 N N   . VAL C 3 564 ? 194.019 213.088 116.769 1.00 268.73 ? 608 VAL C N   1 
ATOM   10530 C CA  . VAL C 3 564 ? 193.631 213.558 118.093 1.00 268.73 ? 608 VAL C CA  1 
ATOM   10531 C C   . VAL C 3 564 ? 192.645 212.562 118.685 1.00 268.73 ? 608 VAL C C   1 
ATOM   10532 O O   . VAL C 3 564 ? 191.586 212.306 118.098 1.00 268.73 ? 608 VAL C O   1 
ATOM   10533 C CB  . VAL C 3 564 ? 193.017 214.966 118.039 1.00 268.73 ? 608 VAL C CB  1 
ATOM   10534 C CG1 . VAL C 3 564 ? 192.420 215.336 119.386 1.00 268.73 ? 608 VAL C CG1 1 
ATOM   10535 C CG2 . VAL C 3 564 ? 194.061 215.985 117.614 1.00 268.73 ? 608 VAL C CG2 1 
ATOM   10536 N N   . ALA C 3 565 ? 192.988 212.004 119.842 1.00 256.27 ? 609 ALA C N   1 
ATOM   10537 C CA  . ALA C 3 565 ? 192.081 211.114 120.550 1.00 256.27 ? 609 ALA C CA  1 
ATOM   10538 C C   . ALA C 3 565 ? 190.996 211.922 121.249 1.00 256.27 ? 609 ALA C C   1 
ATOM   10539 O O   . ALA C 3 565 ? 191.258 212.994 121.803 1.00 256.27 ? 609 ALA C O   1 
ATOM   10540 C CB  . ALA C 3 565 ? 192.843 210.264 121.565 1.00 256.27 ? 609 ALA C CB  1 
ATOM   10541 N N   . LYS C 3 566 ? 189.773 211.402 121.221 1.00 248.20 ? 610 LYS C N   1 
ATOM   10542 C CA  . LYS C 3 566 ? 188.614 212.084 121.777 1.00 248.20 ? 610 LYS C CA  1 
ATOM   10543 C C   . LYS C 3 566 ? 188.161 211.392 123.056 1.00 248.20 ? 610 LYS C C   1 
ATOM   10544 O O   . LYS C 3 566 ? 188.079 210.161 123.113 1.00 248.20 ? 610 LYS C O   1 
ATOM   10545 C CB  . LYS C 3 566 ? 187.463 212.122 120.766 1.00 248.20 ? 610 LYS C CB  1 
ATOM   10546 C CG  . LYS C 3 566 ? 186.330 213.062 121.145 1.00 248.20 ? 610 LYS C CG  1 
ATOM   10547 C CD  . LYS C 3 566 ? 185.120 212.295 121.653 1.00 248.20 ? 610 LYS C CD  1 
ATOM   10548 C CE  . LYS C 3 566 ? 183.951 213.227 121.927 1.00 248.20 ? 610 LYS C CE  1 
ATOM   10549 N NZ  . LYS C 3 566 ? 182.766 212.493 122.451 1.00 248.20 ? 610 LYS C NZ  1 
ATOM   10550 N N   . ASN C 3 567 ? 187.867 212.190 124.075 1.00 230.02 ? 611 ASN C N   1 
ATOM   10551 C CA  . ASN C 3 567 ? 187.386 211.708 125.362 1.00 230.02 ? 611 ASN C CA  1 
ATOM   10552 C C   . ASN C 3 567 ? 186.041 212.356 125.680 1.00 230.02 ? 611 ASN C C   1 
ATOM   10553 O O   . ASN C 3 567 ? 185.487 213.118 124.885 1.00 230.02 ? 611 ASN C O   1 
ATOM   10554 C CB  . ASN C 3 567 ? 188.408 211.991 126.468 1.00 230.02 ? 611 ASN C CB  1 
ATOM   10555 C CG  . ASN C 3 567 ? 189.579 211.030 126.440 1.00 230.02 ? 611 ASN C CG  1 
ATOM   10556 O OD1 . ASN C 3 567 ? 189.760 210.281 125.479 1.00 230.02 ? 611 ASN C OD1 1 
ATOM   10557 N ND2 . ASN C 3 567 ? 190.384 211.046 127.496 1.00 230.02 ? 611 ASN C ND2 1 
ATOM   10558 N N   . SER C 3 568 ? 185.517 212.042 126.865 1.00 227.09 ? 612 SER C N   1 
ATOM   10559 C CA  . SER C 3 568 ? 184.223 212.559 127.288 1.00 227.09 ? 612 SER C CA  1 
ATOM   10560 C C   . SER C 3 568 ? 184.289 213.987 127.813 1.00 227.09 ? 612 SER C C   1 
ATOM   10561 O O   . SER C 3 568 ? 183.240 214.627 127.946 1.00 227.09 ? 612 SER C O   1 
ATOM   10562 C CB  . SER C 3 568 ? 183.620 211.651 128.364 1.00 227.09 ? 612 SER C CB  1 
ATOM   10563 O OG  . SER C 3 568 ? 183.181 210.424 127.811 1.00 227.09 ? 612 SER C OG  1 
ATOM   10564 N N   . VAL C 3 569 ? 185.479 214.501 128.112 1.00 241.59 ? 613 VAL C N   1 
ATOM   10565 C CA  . VAL C 3 569 ? 185.640 215.836 128.665 1.00 241.59 ? 613 VAL C CA  1 
ATOM   10566 C C   . VAL C 3 569 ? 186.287 216.788 127.667 1.00 241.59 ? 613 VAL C C   1 
ATOM   10567 O O   . VAL C 3 569 ? 185.937 217.969 127.618 1.00 241.59 ? 613 VAL C O   1 
ATOM   10568 C CB  . VAL C 3 569 ? 186.442 215.791 129.984 1.00 241.59 ? 613 VAL C CB  1 
ATOM   10569 C CG1 . VAL C 3 569 ? 185.580 215.240 131.109 1.00 241.59 ? 613 VAL C CG1 1 
ATOM   10570 C CG2 . VAL C 3 569 ? 187.700 214.953 129.817 1.00 241.59 ? 613 VAL C CG2 1 
ATOM   10571 N N   . GLY C 3 570 ? 187.220 216.301 126.870 1.00 258.02 ? 614 GLY C N   1 
ATOM   10572 C CA  . GLY C 3 570 ? 187.913 217.135 125.908 1.00 258.02 ? 614 GLY C CA  1 
ATOM   10573 C C   . GLY C 3 570 ? 188.587 216.300 124.847 1.00 258.02 ? 614 GLY C C   1 
ATOM   10574 O O   . GLY C 3 570 ? 188.093 215.239 124.459 1.00 258.02 ? 614 GLY C O   1 
ATOM   10575 N N   . SER C 3 571 ? 189.732 216.785 124.371 1.00 260.50 ? 615 SER C N   1 
ATOM   10576 C CA  . SER C 3 571 ? 190.485 216.120 123.319 1.00 260.50 ? 615 SER C CA  1 
ATOM   10577 C C   . SER C 3 571 ? 191.938 215.961 123.743 1.00 260.50 ? 615 SER C C   1 
ATOM   10578 O O   . SER C 3 571 ? 192.470 216.763 124.515 1.00 260.50 ? 615 SER C O   1 
ATOM   10579 C CB  . SER C 3 571 ? 190.409 216.899 121.999 1.00 260.50 ? 615 SER C CB  1 
ATOM   10580 O OG  . SER C 3 571 ? 191.431 217.877 121.924 1.00 260.50 ? 615 SER C OG  1 
ATOM   10581 N N   . SER C 3 572 ? 192.571 214.913 123.226 1.00 242.32 ? 616 SER C N   1 
ATOM   10582 C CA  . SER C 3 572 ? 193.970 214.659 123.523 1.00 242.32 ? 616 SER C CA  1 
ATOM   10583 C C   . SER C 3 572 ? 194.860 215.656 122.780 1.00 242.32 ? 616 SER C C   1 
ATOM   10584 O O   . SER C 3 572 ? 194.472 216.185 121.735 1.00 242.32 ? 616 SER C O   1 
ATOM   10585 C CB  . SER C 3 572 ? 194.341 213.230 123.133 1.00 242.32 ? 616 SER C CB  1 
ATOM   10586 O OG  . SER C 3 572 ? 195.740 213.080 122.970 1.00 242.32 ? 616 SER C OG  1 
ATOM   10587 N N   . PRO C 3 573 ? 196.045 215.947 123.312 1.00 237.01 ? 617 PRO C N   1 
ATOM   10588 C CA  . PRO C 3 573 ? 196.992 216.810 122.596 1.00 237.01 ? 617 PRO C CA  1 
ATOM   10589 C C   . PRO C 3 573 ? 197.315 216.245 121.225 1.00 237.01 ? 617 PRO C C   1 
ATOM   10590 O O   . PRO C 3 573 ? 197.538 215.034 121.078 1.00 237.01 ? 617 PRO C O   1 
ATOM   10591 C CB  . PRO C 3 573 ? 198.228 216.807 123.507 1.00 237.01 ? 617 PRO C CB  1 
ATOM   10592 C CG  . PRO C 3 573 ? 197.680 216.554 124.866 1.00 237.01 ? 617 PRO C CG  1 
ATOM   10593 C CD  . PRO C 3 573 ? 196.507 215.631 124.675 1.00 237.01 ? 617 PRO C CD  1 
ATOM   10594 N N   . PRO C 3 574 ? 197.344 217.089 120.195 1.00 246.71 ? 618 PRO C N   1 
ATOM   10595 C CA  . PRO C 3 574 ? 197.558 216.583 118.834 1.00 246.71 ? 618 PRO C CA  1 
ATOM   10596 C C   . PRO C 3 574 ? 198.986 216.104 118.624 1.00 246.71 ? 618 PRO C C   1 
ATOM   10597 O O   . PRO C 3 574 ? 199.944 216.697 119.126 1.00 246.71 ? 618 PRO C O   1 
ATOM   10598 C CB  . PRO C 3 574 ? 197.240 217.795 117.952 1.00 246.71 ? 618 PRO C CB  1 
ATOM   10599 C CG  . PRO C 3 574 ? 197.520 218.972 118.825 1.00 246.71 ? 618 PRO C CG  1 
ATOM   10600 C CD  . PRO C 3 574 ? 197.158 218.551 120.223 1.00 246.71 ? 618 PRO C CD  1 
ATOM   10601 N N   . SER C 3 575 ? 199.117 215.014 117.871 1.00 265.46 ? 619 SER C N   1 
ATOM   10602 C CA  . SER C 3 575 ? 200.413 214.449 117.509 1.00 265.46 ? 619 SER C CA  1 
ATOM   10603 C C   . SER C 3 575 ? 200.639 214.692 116.021 1.00 265.46 ? 619 SER C C   1 
ATOM   10604 O O   . SER C 3 575 ? 199.981 214.074 115.177 1.00 265.46 ? 619 SER C O   1 
ATOM   10605 C CB  . SER C 3 575 ? 200.470 212.960 117.841 1.00 265.46 ? 619 SER C CB  1 
ATOM   10606 O OG  . SER C 3 575 ? 199.511 212.234 117.091 1.00 265.46 ? 619 SER C OG  1 
ATOM   10607 N N   . LYS C 3 576 ? 201.566 215.590 115.703 1.00 294.39 ? 620 LYS C N   1 
ATOM   10608 C CA  . LYS C 3 576 ? 201.840 215.963 114.322 1.00 294.39 ? 620 LYS C CA  1 
ATOM   10609 C C   . LYS C 3 576 ? 202.854 215.011 113.703 1.00 294.39 ? 620 LYS C C   1 
ATOM   10610 O O   . LYS C 3 576 ? 203.824 214.606 114.351 1.00 294.39 ? 620 LYS C O   1 
ATOM   10611 C CB  . LYS C 3 576 ? 202.354 217.403 114.247 1.00 294.39 ? 620 LYS C CB  1 
ATOM   10612 C CG  . LYS C 3 576 ? 202.438 217.974 112.836 1.00 294.39 ? 620 LYS C CG  1 
ATOM   10613 C CD  . LYS C 3 576 ? 203.844 217.856 112.263 1.00 294.39 ? 620 LYS C CD  1 
ATOM   10614 C CE  . LYS C 3 576 ? 203.833 217.956 110.746 1.00 294.39 ? 620 LYS C CE  1 
ATOM   10615 N NZ  . LYS C 3 576 ? 205.138 217.551 110.153 1.00 294.39 ? 620 LYS C NZ  1 
ATOM   10616 N N   . ILE C 3 577 ? 202.620 214.657 112.440 1.00 322.72 ? 621 ILE C N   1 
ATOM   10617 C CA  . ILE C 3 577 ? 203.531 213.806 111.685 1.00 322.72 ? 621 ILE C CA  1 
ATOM   10618 C C   . ILE C 3 577 ? 203.439 214.200 110.217 1.00 322.72 ? 621 ILE C C   1 
ATOM   10619 O O   . ILE C 3 577 ? 202.368 214.552 109.715 1.00 322.72 ? 621 ILE C O   1 
ATOM   10620 C CB  . ILE C 3 577 ? 203.221 212.303 111.899 1.00 322.72 ? 621 ILE C CB  1 
ATOM   10621 C CG1 . ILE C 3 577 ? 204.290 211.428 111.241 1.00 322.72 ? 621 ILE C CG1 1 
ATOM   10622 C CG2 . ILE C 3 577 ? 201.831 211.952 111.386 1.00 322.72 ? 621 ILE C CG2 1 
ATOM   10623 C CD1 . ILE C 3 577 ? 204.445 210.067 111.881 1.00 322.72 ? 621 ILE C CD1 1 
ATOM   10624 N N   . ALA C 3 578 ? 204.578 214.158 109.532 1.00 330.73 ? 622 ALA C N   1 
ATOM   10625 C CA  . ALA C 3 578 ? 204.654 214.568 108.139 1.00 330.73 ? 622 ALA C CA  1 
ATOM   10626 C C   . ALA C 3 578 ? 204.245 213.427 107.216 1.00 330.73 ? 622 ALA C C   1 
ATOM   10627 O O   . ALA C 3 578 ? 204.365 212.248 107.559 1.00 330.73 ? 622 ALA C O   1 
ATOM   10628 C CB  . ALA C 3 578 ? 206.066 215.040 107.790 1.00 330.73 ? 622 ALA C CB  1 
ATOM   10629 N N   . SER C 3 579 ? 203.759 213.795 106.029 1.00 332.82 ? 623 SER C N   1 
ATOM   10630 C CA  . SER C 3 579 ? 203.326 212.829 105.031 1.00 332.82 ? 623 SER C CA  1 
ATOM   10631 C C   . SER C 3 579 ? 204.223 212.783 103.803 1.00 332.82 ? 623 SER C C   1 
ATOM   10632 O O   . SER C 3 579 ? 204.117 211.834 103.018 1.00 332.82 ? 623 SER C O   1 
ATOM   10633 C CB  . SER C 3 579 ? 201.885 213.129 104.591 1.00 332.82 ? 623 SER C CB  1 
ATOM   10634 O OG  . SER C 3 579 ? 201.608 212.553 103.326 1.00 332.82 ? 623 SER C OG  1 
ATOM   10635 N N   . MET C 3 580 ? 205.091 213.773 103.612 1.00 321.43 ? 624 MET C N   1 
ATOM   10636 C CA  . MET C 3 580 ? 205.998 213.779 102.473 1.00 321.43 ? 624 MET C CA  1 
ATOM   10637 C C   . MET C 3 580 ? 207.131 212.787 102.706 1.00 321.43 ? 624 MET C C   1 
ATOM   10638 O O   . MET C 3 580 ? 207.730 212.756 103.785 1.00 321.43 ? 624 MET C O   1 
ATOM   10639 C CB  . MET C 3 580 ? 206.558 215.182 102.244 1.00 321.43 ? 624 MET C CB  1 
ATOM   10640 C CG  . MET C 3 580 ? 207.524 215.285 101.076 1.00 321.43 ? 624 MET C CG  1 
ATOM   10641 S SD  . MET C 3 580 ? 208.056 216.978 100.759 1.00 321.43 ? 624 MET C SD  1 
ATOM   10642 C CE  . MET C 3 580 ? 208.754 217.415 102.349 1.00 321.43 ? 624 MET C CE  1 
ATOM   10643 N N   . GLU C 3 581 ? 207.421 211.975 101.693 1.00 318.86 ? 625 GLU C N   1 
ATOM   10644 C CA  . GLU C 3 581 ? 208.482 210.975 101.754 1.00 318.86 ? 625 GLU C CA  1 
ATOM   10645 C C   . GLU C 3 581 ? 209.560 211.358 100.748 1.00 318.86 ? 625 GLU C C   1 
ATOM   10646 O O   . GLU C 3 581 ? 209.377 211.186 99.538  1.00 318.86 ? 625 GLU C O   1 
ATOM   10647 C CB  . GLU C 3 581 ? 207.934 209.578 101.472 1.00 318.86 ? 625 GLU C CB  1 
ATOM   10648 C CG  . GLU C 3 581 ? 208.875 208.453 101.871 1.00 318.86 ? 625 GLU C CG  1 
ATOM   10649 C CD  . GLU C 3 581 ? 208.347 207.086 101.483 1.00 318.86 ? 625 GLU C CD  1 
ATOM   10650 O OE1 . GLU C 3 581 ? 208.005 206.894 100.298 1.00 318.86 ? 625 GLU C OE1 1 
ATOM   10651 O OE2 . GLU C 3 581 ? 208.275 206.204 102.364 1.00 318.86 ? 625 GLU C OE2 1 
ATOM   10652 N N   . ILE C 3 582 ? 210.678 211.874 101.249 1.00 341.71 ? 626 ILE C N   1 
ATOM   10653 C CA  . ILE C 3 582 ? 211.791 212.289 100.400 1.00 341.71 ? 626 ILE C CA  1 
ATOM   10654 C C   . ILE C 3 582 ? 212.491 211.047 99.860  1.00 341.71 ? 626 ILE C C   1 
ATOM   10655 O O   . ILE C 3 582 ? 212.890 210.172 100.643 1.00 341.71 ? 626 ILE C O   1 
ATOM   10656 C CB  . ILE C 3 582 ? 212.771 213.191 101.165 1.00 341.71 ? 626 ILE C CB  1 
ATOM   10657 C CG1 . ILE C 3 582 ? 212.046 214.423 101.711 1.00 341.71 ? 626 ILE C CG1 1 
ATOM   10658 C CG2 . ILE C 3 582 ? 213.928 213.604 100.268 1.00 341.71 ? 626 ILE C CG2 1 
ATOM   10659 C CD1 . ILE C 3 582 ? 211.399 215.276 100.641 1.00 341.71 ? 626 ILE C CD1 1 
ATOM   10660 N N   . PRO C 3 583 ? 212.650 210.919 98.545  1.00 350.02 ? 627 PRO C N   1 
ATOM   10661 C CA  . PRO C 3 583 ? 213.327 209.739 97.997  1.00 350.02 ? 627 PRO C CA  1 
ATOM   10662 C C   . PRO C 3 583 ? 214.804 209.716 98.355  1.00 350.02 ? 627 PRO C C   1 
ATOM   10663 O O   . PRO C 3 583 ? 215.425 210.749 98.617  1.00 350.02 ? 627 PRO C O   1 
ATOM   10664 C CB  . PRO C 3 583 ? 213.125 209.882 96.482  1.00 350.02 ? 627 PRO C CB  1 
ATOM   10665 C CG  . PRO C 3 583 ? 212.002 210.867 96.324  1.00 350.02 ? 627 PRO C CG  1 
ATOM   10666 C CD  . PRO C 3 583 ? 212.121 211.795 97.488  1.00 350.02 ? 627 PRO C CD  1 
ATOM   10667 N N   . ASN C 3 584 ? 215.365 208.508 98.362  1.00 381.04 ? 628 ASN C N   1 
ATOM   10668 C CA  . ASN C 3 584 ? 216.779 208.311 98.674  1.00 381.04 ? 628 ASN C CA  1 
ATOM   10669 C C   . ASN C 3 584 ? 217.266 207.102 97.889  1.00 381.04 ? 628 ASN C C   1 
ATOM   10670 O O   . ASN C 3 584 ? 216.945 205.963 98.242  1.00 381.04 ? 628 ASN C O   1 
ATOM   10671 C CB  . ASN C 3 584 ? 216.992 208.115 100.173 1.00 381.04 ? 628 ASN C CB  1 
ATOM   10672 C CG  . ASN C 3 584 ? 218.178 208.899 100.701 1.00 381.04 ? 628 ASN C CG  1 
ATOM   10673 O OD1 . ASN C 3 584 ? 219.084 209.257 99.950  1.00 381.04 ? 628 ASN C OD1 1 
ATOM   10674 N ND2 . ASN C 3 584 ? 218.180 209.164 102.003 1.00 381.04 ? 628 ASN C ND2 1 
ATOM   10675 N N   . ASP C 3 585 ? 218.037 207.350 96.829  1.00 403.66 ? 629 ASP C N   1 
ATOM   10676 C CA  . ASP C 3 585 ? 218.532 206.271 95.984  1.00 403.66 ? 629 ASP C CA  1 
ATOM   10677 C C   . ASP C 3 585 ? 219.760 205.581 96.562  1.00 403.66 ? 629 ASP C C   1 
ATOM   10678 O O   . ASP C 3 585 ? 220.059 204.448 96.171  1.00 403.66 ? 629 ASP C O   1 
ATOM   10679 C CB  . ASP C 3 585 ? 218.855 206.806 94.587  1.00 403.66 ? 629 ASP C CB  1 
ATOM   10680 C CG  . ASP C 3 585 ? 217.750 207.682 94.029  1.00 403.66 ? 629 ASP C CG  1 
ATOM   10681 O OD1 . ASP C 3 585 ? 218.062 208.629 93.277  1.00 403.66 ? 629 ASP C OD1 1 
ATOM   10682 O OD2 . ASP C 3 585 ? 216.569 207.420 94.338  1.00 403.66 ? 629 ASP C OD2 1 
ATOM   10683 N N   . ASP C 3 586 ? 220.476 206.232 97.479  1.00 419.11 ? 630 ASP C N   1 
ATOM   10684 C CA  . ASP C 3 586 ? 221.676 205.651 98.082  1.00 419.11 ? 630 ASP C CA  1 
ATOM   10685 C C   . ASP C 3 586 ? 221.290 204.806 99.299  1.00 419.11 ? 630 ASP C C   1 
ATOM   10686 O O   . ASP C 3 586 ? 221.544 205.142 100.457 1.00 419.11 ? 630 ASP C O   1 
ATOM   10687 C CB  . ASP C 3 586 ? 222.679 206.749 98.425  1.00 419.11 ? 630 ASP C CB  1 
ATOM   10688 C CG  . ASP C 3 586 ? 222.080 207.847 99.286  1.00 419.11 ? 630 ASP C CG  1 
ATOM   10689 O OD1 . ASP C 3 586 ? 222.121 207.735 100.529 1.00 419.11 ? 630 ASP C OD1 1 
ATOM   10690 O OD2 . ASP C 3 586 ? 221.570 208.832 98.713  1.00 419.11 ? 630 ASP C OD2 1 
ATOM   10691 N N   . LEU C 3 587 ? 220.674 203.666 99.003  1.00 386.57 ? 631 LEU C N   1 
ATOM   10692 C CA  . LEU C 3 587 ? 220.236 202.716 100.015 1.00 386.57 ? 631 LEU C CA  1 
ATOM   10693 C C   . LEU C 3 587 ? 221.081 201.452 99.933  1.00 386.57 ? 631 LEU C C   1 
ATOM   10694 O O   . LEU C 3 587 ? 221.435 200.999 98.839  1.00 386.57 ? 631 LEU C O   1 
ATOM   10695 C CB  . LEU C 3 587 ? 218.749 202.378 99.846  1.00 386.57 ? 631 LEU C CB  1 
ATOM   10696 C CG  . LEU C 3 587 ? 218.283 201.734 98.535  1.00 386.57 ? 631 LEU C CG  1 
ATOM   10697 C CD1 . LEU C 3 587 ? 218.202 200.218 98.656  1.00 386.57 ? 631 LEU C CD1 1 
ATOM   10698 C CD2 . LEU C 3 587 ? 216.945 202.314 98.096  1.00 386.57 ? 631 LEU C CD2 1 
ATOM   10699 N N   . LYS C 3 588 ? 221.408 200.891 101.095 1.00 326.45 ? 632 LYS C N   1 
ATOM   10700 C CA  . LYS C 3 588 ? 222.225 199.689 101.174 1.00 326.45 ? 632 LYS C CA  1 
ATOM   10701 C C   . LYS C 3 588 ? 221.651 198.754 102.226 1.00 326.45 ? 632 LYS C C   1 
ATOM   10702 O O   . LYS C 3 588 ? 221.223 199.196 103.296 1.00 326.45 ? 632 LYS C O   1 
ATOM   10703 C CB  . LYS C 3 588 ? 223.686 200.026 101.505 1.00 326.45 ? 632 LYS C CB  1 
ATOM   10704 C CG  . LYS C 3 588 ? 223.860 200.961 102.692 1.00 326.45 ? 632 LYS C CG  1 
ATOM   10705 C CD  . LYS C 3 588 ? 225.327 201.279 102.935 1.00 326.45 ? 632 LYS C CD  1 
ATOM   10706 C CE  . LYS C 3 588 ? 225.500 202.208 104.127 1.00 326.45 ? 632 LYS C CE  1 
ATOM   10707 N NZ  . LYS C 3 588 ? 224.758 203.487 103.950 1.00 326.45 ? 632 LYS C NZ  1 
ATOM   10708 N N   . ILE C 3 589 ? 221.645 197.461 101.915 1.00 289.79 ? 633 ILE C N   1 
ATOM   10709 C CA  . ILE C 3 589 ? 221.146 196.453 102.843 1.00 289.79 ? 633 ILE C CA  1 
ATOM   10710 C C   . ILE C 3 589 ? 222.248 196.100 103.833 1.00 289.79 ? 633 ILE C C   1 
ATOM   10711 O O   . ILE C 3 589 ? 223.397 195.856 103.444 1.00 289.79 ? 633 ILE C O   1 
ATOM   10712 C CB  . ILE C 3 589 ? 220.651 195.211 102.082 1.00 289.79 ? 633 ILE C CB  1 
ATOM   10713 C CG1 . ILE C 3 589 ? 220.311 194.079 103.054 1.00 289.79 ? 633 ILE C CG1 1 
ATOM   10714 C CG2 . ILE C 3 589 ? 221.678 194.762 101.047 1.00 289.79 ? 633 ILE C CG2 1 
ATOM   10715 C CD1 . ILE C 3 589 ? 219.690 192.871 102.386 1.00 289.79 ? 633 ILE C CD1 1 
ATOM   10716 N N   . GLU C 3 590 ? 221.904 196.084 105.117 1.00 279.10 ? 634 GLU C N   1 
ATOM   10717 C CA  . GLU C 3 590 ? 222.849 195.790 106.182 1.00 279.10 ? 634 GLU C CA  1 
ATOM   10718 C C   . GLU C 3 590 ? 222.339 194.628 107.025 1.00 279.10 ? 634 GLU C C   1 
ATOM   10719 O O   . GLU C 3 590 ? 221.156 194.278 106.989 1.00 279.10 ? 634 GLU C O   1 
ATOM   10720 C CB  . GLU C 3 590 ? 223.085 197.019 107.072 1.00 279.10 ? 634 GLU C CB  1 
ATOM   10721 C CG  . GLU C 3 590 ? 223.421 198.288 106.306 1.00 279.10 ? 634 GLU C CG  1 
ATOM   10722 C CD  . GLU C 3 590 ? 223.604 199.489 107.214 1.00 279.10 ? 634 GLU C CD  1 
ATOM   10723 O OE1 . GLU C 3 590 ? 223.859 199.292 108.421 1.00 279.10 ? 634 GLU C OE1 1 
ATOM   10724 O OE2 . GLU C 3 590 ? 223.492 200.631 106.721 1.00 279.10 ? 634 GLU C OE2 1 
ATOM   10725 N N   . GLN C 3 591 ? 223.250 194.032 107.788 1.00 260.72 ? 635 GLN C N   1 
ATOM   10726 C CA  . GLN C 3 591 ? 222.938 192.908 108.658 1.00 260.72 ? 635 GLN C CA  1 
ATOM   10727 C C   . GLN C 3 591 ? 223.101 193.319 110.115 1.00 260.72 ? 635 GLN C C   1 
ATOM   10728 O O   . GLN C 3 591 ? 223.996 194.100 110.455 1.00 260.72 ? 635 GLN C O   1 
ATOM   10729 C CB  . GLN C 3 591 ? 223.834 191.705 108.345 1.00 260.72 ? 635 GLN C CB  1 
ATOM   10730 C CG  . GLN C 3 591 ? 225.325 192.004 108.382 1.00 260.72 ? 635 GLN C CG  1 
ATOM   10731 C CD  . GLN C 3 591 ? 225.942 191.725 109.738 1.00 260.72 ? 635 GLN C CD  1 
ATOM   10732 O OE1 . GLN C 3 591 ? 225.363 191.016 110.561 1.00 260.72 ? 635 GLN C OE1 1 
ATOM   10733 N NE2 . GLN C 3 591 ? 227.123 192.282 109.978 1.00 260.72 ? 635 GLN C NE2 1 
ATOM   10734 N N   . VAL C 3 592 ? 222.228 192.793 110.972 1.00 262.05 ? 636 VAL C N   1 
ATOM   10735 C CA  . VAL C 3 592 ? 222.263 193.070 112.401 1.00 262.05 ? 636 VAL C CA  1 
ATOM   10736 C C   . VAL C 3 592 ? 222.136 191.757 113.157 1.00 262.05 ? 636 VAL C C   1 
ATOM   10737 O O   . VAL C 3 592 ? 221.555 190.785 112.662 1.00 262.05 ? 636 VAL C O   1 
ATOM   10738 C CB  . VAL C 3 592 ? 221.152 194.055 112.829 1.00 262.05 ? 636 VAL C CB  1 
ATOM   10739 C CG1 . VAL C 3 592 ? 221.490 195.468 112.379 1.00 262.05 ? 636 VAL C CG1 1 
ATOM   10740 C CG2 . VAL C 3 592 ? 219.808 193.615 112.269 1.00 262.05 ? 636 VAL C CG2 1 
ATOM   10741 N N   . VAL C 3 593 ? 222.687 191.732 114.368 1.00 266.38 ? 637 VAL C N   1 
ATOM   10742 C CA  . VAL C 3 593 ? 222.674 190.552 115.224 1.00 266.38 ? 637 VAL C CA  1 
ATOM   10743 C C   . VAL C 3 593 ? 221.978 190.921 116.526 1.00 266.38 ? 637 VAL C C   1 
ATOM   10744 O O   . VAL C 3 593 ? 222.409 191.847 117.225 1.00 266.38 ? 637 VAL C O   1 
ATOM   10745 C CB  . VAL C 3 593 ? 224.092 190.025 115.494 1.00 266.38 ? 637 VAL C CB  1 
ATOM   10746 C CG1 . VAL C 3 593 ? 224.047 188.856 116.466 1.00 266.38 ? 637 VAL C CG1 1 
ATOM   10747 C CG2 . VAL C 3 593 ? 224.765 189.619 114.191 1.00 266.38 ? 637 VAL C CG2 1 
ATOM   10748 N N   . GLY C 3 594 ? 220.906 190.201 116.849 1.00 272.32 ? 638 GLY C N   1 
ATOM   10749 C CA  . GLY C 3 594 ? 220.176 190.462 118.079 1.00 272.32 ? 638 GLY C CA  1 
ATOM   10750 C C   . GLY C 3 594 ? 220.912 189.902 119.281 1.00 272.32 ? 638 GLY C C   1 
ATOM   10751 O O   . GLY C 3 594 ? 221.224 188.707 119.334 1.00 272.32 ? 638 GLY C O   1 
ATOM   10752 N N   . MET C 3 595 ? 221.192 190.768 120.252 1.00 273.01 ? 639 MET C N   1 
ATOM   10753 C CA  . MET C 3 595 ? 221.881 190.384 121.484 1.00 273.01 ? 639 MET C CA  1 
ATOM   10754 C C   . MET C 3 595 ? 220.819 190.069 122.533 1.00 273.01 ? 639 MET C C   1 
ATOM   10755 O O   . MET C 3 595 ? 220.346 190.950 123.251 1.00 273.01 ? 639 MET C O   1 
ATOM   10756 C CB  . MET C 3 595 ? 222.824 191.488 121.950 1.00 273.01 ? 639 MET C CB  1 
ATOM   10757 C CG  . MET C 3 595 ? 223.786 191.992 120.883 1.00 273.01 ? 639 MET C CG  1 
ATOM   10758 S SD  . MET C 3 595 ? 224.210 190.749 119.646 1.00 273.01 ? 639 MET C SD  1 
ATOM   10759 C CE  . MET C 3 595 ? 225.330 189.706 120.579 1.00 273.01 ? 639 MET C CE  1 
ATOM   10760 N N   . GLY C 3 596 ? 220.448 188.802 122.617 1.00 273.52 ? 640 GLY C N   1 
ATOM   10761 C CA  . GLY C 3 596 ? 219.443 188.359 123.585 1.00 273.52 ? 640 GLY C CA  1 
ATOM   10762 C C   . GLY C 3 596 ? 218.023 188.500 123.031 1.00 273.52 ? 640 GLY C C   1 
ATOM   10763 O O   . GLY C 3 596 ? 217.662 187.819 122.075 1.00 273.52 ? 640 GLY C O   1 
ATOM   10764 N N   . LYS C 3 597 ? 217.237 189.385 123.643 1.00 279.48 ? 641 LYS C N   1 
ATOM   10765 C CA  . LYS C 3 597 ? 215.859 189.604 123.222 1.00 279.48 ? 641 LYS C CA  1 
ATOM   10766 C C   . LYS C 3 597 ? 215.717 190.765 122.249 1.00 279.48 ? 641 LYS C C   1 
ATOM   10767 O O   . LYS C 3 597 ? 214.908 190.687 121.317 1.00 279.48 ? 641 LYS C O   1 
ATOM   10768 C CB  . LYS C 3 597 ? 214.970 189.848 124.445 1.00 279.48 ? 641 LYS C CB  1 
ATOM   10769 C CG  . LYS C 3 597 ? 213.489 189.985 124.126 1.00 279.48 ? 641 LYS C CG  1 
ATOM   10770 C CD  . LYS C 3 597 ? 212.967 188.763 123.389 1.00 279.48 ? 641 LYS C CD  1 
ATOM   10771 C CE  . LYS C 3 597 ? 211.505 188.932 123.007 1.00 279.48 ? 641 LYS C CE  1 
ATOM   10772 N NZ  . LYS C 3 597 ? 210.970 187.727 122.315 1.00 279.48 ? 641 LYS C NZ  1 
ATOM   10773 N N   . GLY C 3 598 ? 216.485 191.836 122.436 1.00 297.28 ? 642 GLY C N   1 
ATOM   10774 C CA  . GLY C 3 598 ? 216.389 192.991 121.567 1.00 297.28 ? 642 GLY C CA  1 
ATOM   10775 C C   . GLY C 3 598 ? 217.524 193.092 120.570 1.00 297.28 ? 642 GLY C C   1 
ATOM   10776 O O   . GLY C 3 598 ? 218.617 192.569 120.806 1.00 297.28 ? 642 GLY C O   1 
ATOM   10777 N N   . ILE C 3 599 ? 217.275 193.764 119.450 1.00 314.59 ? 643 ILE C N   1 
ATOM   10778 C CA  . ILE C 3 599 ? 218.262 193.941 118.390 1.00 314.59 ? 643 ILE C CA  1 
ATOM   10779 C C   . ILE C 3 599 ? 218.737 195.386 118.426 1.00 314.59 ? 643 ILE C C   1 
ATOM   10780 O O   . ILE C 3 599 ? 217.921 196.317 118.410 1.00 314.59 ? 643 ILE C O   1 
ATOM   10781 C CB  . ILE C 3 599 ? 217.687 193.581 117.012 1.00 314.59 ? 643 ILE C CB  1 
ATOM   10782 C CG1 . ILE C 3 599 ? 217.061 192.185 117.045 1.00 314.59 ? 643 ILE C CG1 1 
ATOM   10783 C CG2 . ILE C 3 599 ? 218.771 193.659 115.947 1.00 314.59 ? 643 ILE C CG2 1 
ATOM   10784 C CD1 . ILE C 3 599 ? 216.492 191.739 115.716 1.00 314.59 ? 643 ILE C CD1 1 
ATOM   10785 N N   . LEU C 3 600 ? 220.053 195.574 118.475 1.00 352.89 ? 644 LEU C N   1 
ATOM   10786 C CA  . LEU C 3 600 ? 220.630 196.909 118.521 1.00 352.89 ? 644 LEU C CA  1 
ATOM   10787 C C   . LEU C 3 600 ? 220.688 197.514 117.125 1.00 352.89 ? 644 LEU C C   1 
ATOM   10788 O O   . LEU C 3 600 ? 220.868 196.806 116.130 1.00 352.89 ? 644 LEU C O   1 
ATOM   10789 C CB  . LEU C 3 600 ? 222.027 196.859 119.146 1.00 352.89 ? 644 LEU C CB  1 
ATOM   10790 C CG  . LEU C 3 600 ? 223.172 196.191 118.375 1.00 352.89 ? 644 LEU C CG  1 
ATOM   10791 C CD1 . LEU C 3 600 ? 223.972 197.199 117.555 1.00 352.89 ? 644 LEU C CD1 1 
ATOM   10792 C CD2 . LEU C 3 600 ? 224.082 195.424 119.325 1.00 352.89 ? 644 LEU C CD2 1 
ATOM   10793 N N   . LEU C 3 601 ? 220.531 198.835 117.057 1.00 376.67 ? 645 LEU C N   1 
ATOM   10794 C CA  . LEU C 3 601 ? 220.577 199.573 115.800 1.00 376.67 ? 645 LEU C CA  1 
ATOM   10795 C C   . LEU C 3 601 ? 221.594 200.695 115.934 1.00 376.67 ? 645 LEU C C   1 
ATOM   10796 O O   . LEU C 3 601 ? 221.503 201.509 116.859 1.00 376.67 ? 645 LEU C O   1 
ATOM   10797 C CB  . LEU C 3 601 ? 219.200 200.134 115.429 1.00 376.67 ? 645 LEU C CB  1 
ATOM   10798 C CG  . LEU C 3 601 ? 218.005 199.178 115.479 1.00 376.67 ? 645 LEU C CG  1 
ATOM   10799 C CD1 . LEU C 3 601 ? 217.288 199.268 116.818 1.00 376.67 ? 645 LEU C CD1 1 
ATOM   10800 C CD2 . LEU C 3 601 ? 217.045 199.462 114.333 1.00 376.67 ? 645 LEU C CD2 1 
ATOM   10801 N N   . THR C 3 602 ? 222.556 200.736 115.017 1.00 403.84 ? 646 THR C N   1 
ATOM   10802 C CA  . THR C 3 602 ? 223.621 201.730 115.029 1.00 403.84 ? 646 THR C CA  1 
ATOM   10803 C C   . THR C 3 602 ? 223.567 202.548 113.748 1.00 403.84 ? 646 THR C C   1 
ATOM   10804 O O   . THR C 3 602 ? 223.600 201.987 112.647 1.00 403.84 ? 646 THR C O   1 
ATOM   10805 C CB  . THR C 3 602 ? 224.995 201.068 115.172 1.00 403.84 ? 646 THR C CB  1 
ATOM   10806 O OG1 . THR C 3 602 ? 225.066 199.921 114.316 1.00 403.84 ? 646 THR C OG1 1 
ATOM   10807 C CG2 . THR C 3 602 ? 225.231 200.635 116.612 1.00 403.84 ? 646 THR C CG2 1 
ATOM   10808 N N   . TRP C 3 603 ? 223.483 203.869 113.893 1.00 392.35 ? 647 TRP C N   1 
ATOM   10809 C CA  . TRP C 3 603 ? 223.500 204.767 112.749 1.00 392.35 ? 647 TRP C CA  1 
ATOM   10810 C C   . TRP C 3 603 ? 224.223 206.048 113.138 1.00 392.35 ? 647 TRP C C   1 
ATOM   10811 O O   . TRP C 3 603 ? 224.270 206.427 114.311 1.00 392.35 ? 647 TRP C O   1 
ATOM   10812 C CB  . TRP C 3 603 ? 222.084 205.077 112.245 1.00 392.35 ? 647 TRP C CB  1 
ATOM   10813 C CG  . TRP C 3 603 ? 221.225 205.803 113.238 1.00 392.35 ? 647 TRP C CG  1 
ATOM   10814 C CD1 . TRP C 3 603 ? 221.187 207.150 113.459 1.00 392.35 ? 647 TRP C CD1 1 
ATOM   10815 C CD2 . TRP C 3 603 ? 220.270 205.223 114.135 1.00 392.35 ? 647 TRP C CD2 1 
ATOM   10816 N NE1 . TRP C 3 603 ? 220.274 207.443 114.443 1.00 392.35 ? 647 TRP C NE1 1 
ATOM   10817 C CE2 . TRP C 3 603 ? 219.697 206.277 114.874 1.00 392.35 ? 647 TRP C CE2 1 
ATOM   10818 C CE3 . TRP C 3 603 ? 219.847 203.915 114.388 1.00 392.35 ? 647 TRP C CE3 1 
ATOM   10819 C CZ2 . TRP C 3 603 ? 218.723 206.064 115.847 1.00 392.35 ? 647 TRP C CZ2 1 
ATOM   10820 C CZ3 . TRP C 3 603 ? 218.880 203.705 115.355 1.00 392.35 ? 647 TRP C CZ3 1 
ATOM   10821 C CH2 . TRP C 3 603 ? 218.329 204.774 116.072 1.00 392.35 ? 647 TRP C CH2 1 
ATOM   10822 N N   . HIS C 3 604 ? 224.788 206.711 112.134 1.00 391.05 ? 648 HIS C N   1 
ATOM   10823 C CA  . HIS C 3 604 ? 225.519 207.947 112.362 1.00 391.05 ? 648 HIS C CA  1 
ATOM   10824 C C   . HIS C 3 604 ? 224.560 209.114 112.563 1.00 391.05 ? 648 HIS C C   1 
ATOM   10825 O O   . HIS C 3 604 ? 223.471 209.160 111.983 1.00 391.05 ? 648 HIS C O   1 
ATOM   10826 C CB  . HIS C 3 604 ? 226.459 208.238 111.192 1.00 391.05 ? 648 HIS C CB  1 
ATOM   10827 C CG  . HIS C 3 604 ? 227.499 207.183 110.975 1.00 391.05 ? 648 HIS C CG  1 
ATOM   10828 N ND1 . HIS C 3 604 ? 228.545 206.978 111.849 1.00 391.05 ? 648 HIS C ND1 1 
ATOM   10829 C CD2 . HIS C 3 604 ? 227.655 206.274 109.984 1.00 391.05 ? 648 HIS C CD2 1 
ATOM   10830 C CE1 . HIS C 3 604 ? 229.299 205.988 111.406 1.00 391.05 ? 648 HIS C CE1 1 
ATOM   10831 N NE2 . HIS C 3 604 ? 228.781 205.544 110.276 1.00 391.05 ? 648 HIS C NE2 1 
ATOM   10832 N N   . TYR C 3 605 ? 224.978 210.063 113.397 1.00 385.29 ? 649 TYR C N   1 
ATOM   10833 C CA  . TYR C 3 605 ? 224.157 211.233 113.677 1.00 385.29 ? 649 TYR C CA  1 
ATOM   10834 C C   . TYR C 3 605 ? 224.113 212.151 112.462 1.00 385.29 ? 649 TYR C C   1 
ATOM   10835 O O   . TYR C 3 605 ? 225.152 212.493 111.889 1.00 385.29 ? 649 TYR C O   1 
ATOM   10836 C CB  . TYR C 3 605 ? 224.702 211.984 114.891 1.00 385.29 ? 649 TYR C CB  1 
ATOM   10837 C CG  . TYR C 3 605 ? 224.025 213.313 115.148 1.00 385.29 ? 649 TYR C CG  1 
ATOM   10838 C CD1 . TYR C 3 605 ? 224.648 214.508 114.813 1.00 385.29 ? 649 TYR C CD1 1 
ATOM   10839 C CD2 . TYR C 3 605 ? 222.763 213.371 115.726 1.00 385.29 ? 649 TYR C CD2 1 
ATOM   10840 C CE1 . TYR C 3 605 ? 224.034 215.724 115.046 1.00 385.29 ? 649 TYR C CE1 1 
ATOM   10841 C CE2 . TYR C 3 605 ? 222.141 214.582 115.962 1.00 385.29 ? 649 TYR C CE2 1 
ATOM   10842 C CZ  . TYR C 3 605 ? 222.781 215.755 115.620 1.00 385.29 ? 649 TYR C CZ  1 
ATOM   10843 O OH  . TYR C 3 605 ? 222.165 216.963 115.854 1.00 385.29 ? 649 TYR C OH  1 
ATOM   10844 N N   . ASP C 3 606 ? 222.904 212.551 112.071 1.00 364.17 ? 650 ASP C N   1 
ATOM   10845 C CA  . ASP C 3 606 ? 222.708 213.432 110.929 1.00 364.17 ? 650 ASP C CA  1 
ATOM   10846 C C   . ASP C 3 606 ? 222.230 214.789 111.422 1.00 364.17 ? 650 ASP C C   1 
ATOM   10847 O O   . ASP C 3 606 ? 221.155 214.872 112.035 1.00 364.17 ? 650 ASP C O   1 
ATOM   10848 C CB  . ASP C 3 606 ? 221.699 212.830 109.953 1.00 364.17 ? 650 ASP C CB  1 
ATOM   10849 C CG  . ASP C 3 606 ? 221.976 213.218 108.514 1.00 364.17 ? 650 ASP C CG  1 
ATOM   10850 O OD1 . ASP C 3 606 ? 221.612 212.441 107.607 1.00 364.17 ? 650 ASP C OD1 1 
ATOM   10851 O OD2 . ASP C 3 606 ? 222.559 214.299 108.289 1.00 364.17 ? 650 ASP C OD2 1 
ATOM   10852 N N   . PRO C 3 607 ? 222.980 215.869 111.185 1.00 354.10 ? 651 PRO C N   1 
ATOM   10853 C CA  . PRO C 3 607 ? 222.572 217.175 111.728 1.00 354.10 ? 651 PRO C CA  1 
ATOM   10854 C C   . PRO C 3 607 ? 221.369 217.785 111.028 1.00 354.10 ? 651 PRO C C   1 
ATOM   10855 O O   . PRO C 3 607 ? 220.763 218.711 111.581 1.00 354.10 ? 651 PRO C O   1 
ATOM   10856 C CB  . PRO C 3 607 ? 223.824 218.040 111.537 1.00 354.10 ? 651 PRO C CB  1 
ATOM   10857 C CG  . PRO C 3 607 ? 224.530 217.418 110.380 1.00 354.10 ? 651 PRO C CG  1 
ATOM   10858 C CD  . PRO C 3 607 ? 224.269 215.939 110.477 1.00 354.10 ? 651 PRO C CD  1 
ATOM   10859 N N   . ASN C 3 608 ? 221.002 217.306 109.840 1.00 353.73 ? 652 ASN C N   1 
ATOM   10860 C CA  . ASN C 3 608 ? 219.880 217.885 109.111 1.00 353.73 ? 652 ASN C CA  1 
ATOM   10861 C C   . ASN C 3 608 ? 218.525 217.391 109.604 1.00 353.73 ? 652 ASN C C   1 
ATOM   10862 O O   . ASN C 3 608 ? 217.498 217.918 109.164 1.00 353.73 ? 652 ASN C O   1 
ATOM   10863 C CB  . ASN C 3 608 ? 220.020 217.603 107.612 1.00 353.73 ? 652 ASN C CB  1 
ATOM   10864 C CG  . ASN C 3 608 ? 220.243 216.132 107.308 1.00 353.73 ? 652 ASN C CG  1 
ATOM   10865 O OD1 . ASN C 3 608 ? 219.789 215.255 108.042 1.00 353.73 ? 652 ASN C OD1 1 
ATOM   10866 N ND2 . ASN C 3 608 ? 220.947 215.857 106.216 1.00 353.73 ? 652 ASN C ND2 1 
ATOM   10867 N N   . MET C 3 609 ? 218.496 216.399 110.491 1.00 365.06 ? 653 MET C N   1 
ATOM   10868 C CA  . MET C 3 609 ? 217.230 215.895 111.004 1.00 365.06 ? 653 MET C CA  1 
ATOM   10869 C C   . MET C 3 609 ? 216.568 216.932 111.903 1.00 365.06 ? 653 MET C C   1 
ATOM   10870 O O   . MET C 3 609 ? 217.230 217.600 112.702 1.00 365.06 ? 653 MET C O   1 
ATOM   10871 C CB  . MET C 3 609 ? 217.448 214.589 111.765 1.00 365.06 ? 653 MET C CB  1 
ATOM   10872 C CG  . MET C 3 609 ? 218.038 213.486 110.905 1.00 365.06 ? 653 MET C CG  1 
ATOM   10873 S SD  . MET C 3 609 ? 217.278 213.431 109.271 1.00 365.06 ? 653 MET C SD  1 
ATOM   10874 C CE  . MET C 3 609 ? 218.365 212.287 108.427 1.00 365.06 ? 653 MET C CE  1 
ATOM   10875 N N   . THR C 3 610 ? 215.248 217.063 111.768 1.00 380.38 ? 654 THR C N   1 
ATOM   10876 C CA  . THR C 3 610 ? 214.506 218.142 112.408 1.00 380.38 ? 654 THR C CA  1 
ATOM   10877 C C   . THR C 3 610 ? 213.686 217.674 113.604 1.00 380.38 ? 654 THR C C   1 
ATOM   10878 O O   . THR C 3 610 ? 213.859 218.197 114.708 1.00 380.38 ? 654 THR C O   1 
ATOM   10879 C CB  . THR C 3 610 ? 213.595 218.831 111.382 1.00 380.38 ? 654 THR C CB  1 
ATOM   10880 O OG1 . THR C 3 610 ? 212.458 218.000 111.114 1.00 380.38 ? 654 THR C OG1 1 
ATOM   10881 C CG2 . THR C 3 610 ? 214.348 219.090 110.086 1.00 380.38 ? 654 THR C CG2 1 
ATOM   10882 N N   . CYS C 3 611 ? 212.793 216.698 113.424 1.00 403.11 ? 655 CYS C N   1 
ATOM   10883 C CA  . CYS C 3 611 ? 211.811 216.375 114.456 1.00 403.11 ? 655 CYS C CA  1 
ATOM   10884 C C   . CYS C 3 611 ? 212.214 215.173 115.306 1.00 403.11 ? 655 CYS C C   1 
ATOM   10885 O O   . CYS C 3 611 ? 212.380 215.311 116.522 1.00 403.11 ? 655 CYS C O   1 
ATOM   10886 C CB  . CYS C 3 611 ? 210.434 216.155 113.811 1.00 403.11 ? 655 CYS C CB  1 
ATOM   10887 S SG  . CYS C 3 611 ? 210.251 214.637 112.851 1.00 403.11 ? 655 CYS C SG  1 
ATOM   10888 N N   . ASP C 3 612 ? 212.394 214.006 114.698 1.00 399.18 ? 656 ASP C N   1 
ATOM   10889 C CA  . ASP C 3 612 ? 212.783 212.804 115.438 1.00 399.18 ? 656 ASP C CA  1 
ATOM   10890 C C   . ASP C 3 612 ? 213.186 211.725 114.435 1.00 399.18 ? 656 ASP C C   1 
ATOM   10891 O O   . ASP C 3 612 ? 213.313 211.986 113.233 1.00 399.18 ? 656 ASP C O   1 
ATOM   10892 C CB  . ASP C 3 612 ? 211.664 212.334 116.375 1.00 399.18 ? 656 ASP C CB  1 
ATOM   10893 C CG  . ASP C 3 612 ? 210.403 211.904 115.637 1.00 399.18 ? 656 ASP C CG  1 
ATOM   10894 O OD1 . ASP C 3 612 ? 210.351 212.000 114.394 1.00 399.18 ? 656 ASP C OD1 1 
ATOM   10895 O OD2 . ASP C 3 612 ? 209.450 211.466 116.315 1.00 399.18 ? 656 ASP C OD2 1 
ATOM   10896 N N   . TYR C 3 613 ? 213.390 210.509 114.938 1.00 384.17 ? 657 TYR C N   1 
ATOM   10897 C CA  . TYR C 3 613 ? 213.696 209.343 114.121 1.00 384.17 ? 657 TYR C CA  1 
ATOM   10898 C C   . TYR C 3 613 ? 212.576 208.321 114.263 1.00 384.17 ? 657 TYR C C   1 
ATOM   10899 O O   . TYR C 3 613 ? 211.981 208.185 115.337 1.00 384.17 ? 657 TYR C O   1 
ATOM   10900 C CB  . TYR C 3 613 ? 215.029 208.706 114.531 1.00 384.17 ? 657 TYR C CB  1 
ATOM   10901 C CG  . TYR C 3 613 ? 216.255 209.481 114.101 1.00 384.17 ? 657 TYR C CG  1 
ATOM   10902 C CD1 . TYR C 3 613 ? 216.842 209.259 112.862 1.00 384.17 ? 657 TYR C CD1 1 
ATOM   10903 C CD2 . TYR C 3 613 ? 216.831 210.426 114.939 1.00 384.17 ? 657 TYR C CD2 1 
ATOM   10904 C CE1 . TYR C 3 613 ? 217.965 209.962 112.468 1.00 384.17 ? 657 TYR C CE1 1 
ATOM   10905 C CE2 . TYR C 3 613 ? 217.954 211.133 114.554 1.00 384.17 ? 657 TYR C CE2 1 
ATOM   10906 C CZ  . TYR C 3 613 ? 218.516 210.897 113.318 1.00 384.17 ? 657 TYR C CZ  1 
ATOM   10907 O OH  . TYR C 3 613 ? 219.635 211.600 112.932 1.00 384.17 ? 657 TYR C OH  1 
ATOM   10908 N N   . VAL C 3 614 ? 212.292 207.604 113.178 1.00 333.87 ? 658 VAL C N   1 
ATOM   10909 C CA  . VAL C 3 614 ? 211.257 206.577 113.157 1.00 333.87 ? 658 VAL C CA  1 
ATOM   10910 C C   . VAL C 3 614 ? 211.849 205.306 112.565 1.00 333.87 ? 658 VAL C C   1 
ATOM   10911 O O   . VAL C 3 614 ? 212.450 205.341 111.486 1.00 333.87 ? 658 VAL C O   1 
ATOM   10912 C CB  . VAL C 3 614 ? 210.021 207.024 112.352 1.00 333.87 ? 658 VAL C CB  1 
ATOM   10913 C CG1 . VAL C 3 614 ? 209.050 205.865 112.181 1.00 333.87 ? 658 VAL C CG1 1 
ATOM   10914 C CG2 . VAL C 3 614 ? 209.336 208.197 113.036 1.00 333.87 ? 658 VAL C CG2 1 
ATOM   10915 N N   . ILE C 3 615 ? 211.679 204.190 113.270 1.00 307.07 ? 659 ILE C N   1 
ATOM   10916 C CA  . ILE C 3 615 ? 212.160 202.887 112.825 1.00 307.07 ? 659 ILE C CA  1 
ATOM   10917 C C   . ILE C 3 615 ? 210.978 201.928 112.816 1.00 307.07 ? 659 ILE C C   1 
ATOM   10918 O O   . ILE C 3 615 ? 210.323 201.736 113.848 1.00 307.07 ? 659 ILE C O   1 
ATOM   10919 C CB  . ILE C 3 615 ? 213.289 202.343 113.718 1.00 307.07 ? 659 ILE C CB  1 
ATOM   10920 C CG1 . ILE C 3 615 ? 214.532 203.234 113.629 1.00 307.07 ? 659 ILE C CG1 1 
ATOM   10921 C CG2 . ILE C 3 615 ? 213.627 200.909 113.335 1.00 307.07 ? 659 ILE C CG2 1 
ATOM   10922 C CD1 . ILE C 3 615 ? 214.583 204.339 114.665 1.00 307.07 ? 659 ILE C CD1 1 
ATOM   10923 N N   . LYS C 3 616 ? 210.708 201.328 111.660 1.00 315.99 ? 660 LYS C N   1 
ATOM   10924 C CA  . LYS C 3 616 ? 209.615 200.383 111.499 1.00 315.99 ? 660 LYS C CA  1 
ATOM   10925 C C   . LYS C 3 616 ? 210.164 199.011 111.130 1.00 315.99 ? 660 LYS C C   1 
ATOM   10926 O O   . LYS C 3 616 ? 211.278 198.880 110.617 1.00 315.99 ? 660 LYS C O   1 
ATOM   10927 C CB  . LYS C 3 616 ? 208.620 200.859 110.431 1.00 315.99 ? 660 LYS C CB  1 
ATOM   10928 C CG  . LYS C 3 616 ? 209.147 200.783 109.008 1.00 315.99 ? 660 LYS C CG  1 
ATOM   10929 C CD  . LYS C 3 616 ? 208.148 201.365 108.021 1.00 315.99 ? 660 LYS C CD  1 
ATOM   10930 C CE  . LYS C 3 616 ? 208.562 201.090 106.585 1.00 315.99 ? 660 LYS C CE  1 
ATOM   10931 N NZ  . LYS C 3 616 ? 208.474 199.642 106.250 1.00 315.99 ? 660 LYS C NZ  1 
ATOM   10932 N N   . TRP C 3 617 ? 209.363 197.982 111.403 1.00 318.19 ? 661 TRP C N   1 
ATOM   10933 C CA  . TRP C 3 617 ? 209.769 196.609 111.145 1.00 318.19 ? 661 TRP C CA  1 
ATOM   10934 C C   . TRP C 3 617 ? 208.531 195.730 111.060 1.00 318.19 ? 661 TRP C C   1 
ATOM   10935 O O   . TRP C 3 617 ? 207.494 196.039 111.654 1.00 318.19 ? 661 TRP C O   1 
ATOM   10936 C CB  . TRP C 3 617 ? 210.715 196.091 112.235 1.00 318.19 ? 661 TRP C CB  1 
ATOM   10937 C CG  . TRP C 3 617 ? 210.056 195.938 113.573 1.00 318.19 ? 661 TRP C CG  1 
ATOM   10938 C CD1 . TRP C 3 617 ? 209.559 194.789 114.116 1.00 318.19 ? 661 TRP C CD1 1 
ATOM   10939 C CD2 . TRP C 3 617 ? 209.817 196.972 114.535 1.00 318.19 ? 661 TRP C CD2 1 
ATOM   10940 N NE1 . TRP C 3 617 ? 209.028 195.043 115.357 1.00 318.19 ? 661 TRP C NE1 1 
ATOM   10941 C CE2 . TRP C 3 617 ? 209.174 196.376 115.638 1.00 318.19 ? 661 TRP C CE2 1 
ATOM   10942 C CE3 . TRP C 3 617 ? 210.087 198.344 114.573 1.00 318.19 ? 661 TRP C CE3 1 
ATOM   10943 C CZ2 . TRP C 3 617 ? 208.796 197.103 116.765 1.00 318.19 ? 661 TRP C CZ2 1 
ATOM   10944 C CZ3 . TRP C 3 617 ? 209.710 199.064 115.692 1.00 318.19 ? 661 TRP C CZ3 1 
ATOM   10945 C CH2 . TRP C 3 617 ? 209.072 198.443 116.773 1.00 318.19 ? 661 TRP C CH2 1 
ATOM   10946 N N   . CYS C 3 618 ? 208.652 194.633 110.317 1.00 328.65 ? 662 CYS C N   1 
ATOM   10947 C CA  . CYS C 3 618 ? 207.570 193.664 110.194 1.00 328.65 ? 662 CYS C CA  1 
ATOM   10948 C C   . CYS C 3 618 ? 208.179 192.298 109.894 1.00 328.65 ? 662 CYS C C   1 
ATOM   10949 O O   . CYS C 3 618 ? 209.402 192.125 109.912 1.00 328.65 ? 662 CYS C O   1 
ATOM   10950 C CB  . CYS C 3 618 ? 206.568 194.089 109.117 1.00 328.65 ? 662 CYS C CB  1 
ATOM   10951 S SG  . CYS C 3 618 ? 207.086 193.765 107.411 1.00 328.65 ? 662 CYS C SG  1 
ATOM   10952 N N   . ASN C 3 619 ? 207.318 191.326 109.610 1.00 311.72 ? 663 ASN C N   1 
ATOM   10953 C CA  . ASN C 3 619 ? 207.746 189.972 109.284 1.00 311.72 ? 663 ASN C CA  1 
ATOM   10954 C C   . ASN C 3 619 ? 207.956 189.861 107.778 1.00 311.72 ? 663 ASN C C   1 
ATOM   10955 O O   . ASN C 3 619 ? 207.028 190.099 106.997 1.00 311.72 ? 663 ASN C O   1 
ATOM   10956 C CB  . ASN C 3 619 ? 206.715 188.951 109.763 1.00 311.72 ? 663 ASN C CB  1 
ATOM   10957 C CG  . ASN C 3 619 ? 207.288 187.551 109.879 1.00 311.72 ? 663 ASN C CG  1 
ATOM   10958 O OD1 . ASN C 3 619 ? 208.192 187.173 109.135 1.00 311.72 ? 663 ASN C OD1 1 
ATOM   10959 N ND2 . ASN C 3 619 ? 206.760 186.773 110.817 1.00 311.72 ? 663 ASN C ND2 1 
ATOM   10960 N N   . SER C 3 620 ? 209.172 189.499 107.375 1.00 291.28 ? 664 SER C N   1 
ATOM   10961 C CA  . SER C 3 620 ? 209.515 189.337 105.969 1.00 291.28 ? 664 SER C CA  1 
ATOM   10962 C C   . SER C 3 620 ? 209.398 187.896 105.493 1.00 291.28 ? 664 SER C C   1 
ATOM   10963 O O   . SER C 3 620 ? 209.707 187.616 104.330 1.00 291.28 ? 664 SER C O   1 
ATOM   10964 C CB  . SER C 3 620 ? 210.935 189.850 105.710 1.00 291.28 ? 664 SER C CB  1 
ATOM   10965 O OG  . SER C 3 620 ? 211.832 189.395 106.707 1.00 291.28 ? 664 SER C OG  1 
ATOM   10966 N N   . SER C 3 621 ? 208.961 186.978 106.356 1.00 296.08 ? 665 SER C N   1 
ATOM   10967 C CA  . SER C 3 621 ? 208.815 185.571 106.008 1.00 296.08 ? 665 SER C CA  1 
ATOM   10968 C C   . SER C 3 621 ? 207.361 185.186 105.754 1.00 296.08 ? 665 SER C C   1 
ATOM   10969 O O   . SER C 3 621 ? 207.001 184.009 105.865 1.00 296.08 ? 665 SER C O   1 
ATOM   10970 C CB  . SER C 3 621 ? 209.414 184.690 107.104 1.00 296.08 ? 665 SER C CB  1 
ATOM   10971 O OG  . SER C 3 621 ? 210.672 185.187 107.527 1.00 296.08 ? 665 SER C OG  1 
ATOM   10972 N N   . ARG C 3 622 ? 206.517 186.158 105.414 1.00 333.17 ? 666 ARG C N   1 
ATOM   10973 C CA  . ARG C 3 622 ? 205.105 185.911 105.161 1.00 333.17 ? 666 ARG C CA  1 
ATOM   10974 C C   . ARG C 3 622 ? 204.645 186.758 103.985 1.00 333.17 ? 666 ARG C C   1 
ATOM   10975 O O   . ARG C 3 622 ? 205.025 187.926 103.866 1.00 333.17 ? 666 ARG C O   1 
ATOM   10976 C CB  . ARG C 3 622 ? 204.249 186.226 106.395 1.00 333.17 ? 666 ARG C CB  1 
ATOM   10977 C CG  . ARG C 3 622 ? 204.298 185.164 107.481 1.00 333.17 ? 666 ARG C CG  1 
ATOM   10978 C CD  . ARG C 3 622 ? 203.345 185.500 108.617 1.00 333.17 ? 666 ARG C CD  1 
ATOM   10979 N NE  . ARG C 3 622 ? 203.292 184.443 109.622 1.00 333.17 ? 666 ARG C NE  1 
ATOM   10980 C CZ  . ARG C 3 622 ? 202.500 184.467 110.689 1.00 333.17 ? 666 ARG C CZ  1 
ATOM   10981 N NH1 . ARG C 3 622 ? 201.691 185.497 110.894 1.00 333.17 ? 666 ARG C NH1 1 
ATOM   10982 N NH2 . ARG C 3 622 ? 202.518 183.461 111.553 1.00 333.17 ? 666 ARG C NH2 1 
ATOM   10983 N N   . SER C 3 623 ? 203.825 186.162 103.119 1.00 359.06 ? 667 SER C N   1 
ATOM   10984 C CA  . SER C 3 623 ? 203.255 186.887 101.991 1.00 359.06 ? 667 SER C CA  1 
ATOM   10985 C C   . SER C 3 623 ? 202.076 187.764 102.390 1.00 359.06 ? 667 SER C C   1 
ATOM   10986 O O   . SER C 3 623 ? 201.689 188.643 101.612 1.00 359.06 ? 667 SER C O   1 
ATOM   10987 C CB  . SER C 3 623 ? 202.819 185.905 100.901 1.00 359.06 ? 667 SER C CB  1 
ATOM   10988 O OG  . SER C 3 623 ? 203.938 185.397 100.195 1.00 359.06 ? 667 SER C OG  1 
ATOM   10989 N N   . GLU C 3 624 ? 201.501 187.547 103.570 1.00 371.52 ? 668 GLU C N   1 
ATOM   10990 C CA  . GLU C 3 624 ? 200.411 188.377 104.046 1.00 371.52 ? 668 GLU C CA  1 
ATOM   10991 C C   . GLU C 3 624 ? 200.930 189.764 104.422 1.00 371.52 ? 668 GLU C C   1 
ATOM   10992 O O   . GLU C 3 624 ? 202.128 189.946 104.652 1.00 371.52 ? 668 GLU C O   1 
ATOM   10993 C CB  . GLU C 3 624 ? 199.735 187.719 105.247 1.00 371.52 ? 668 GLU C CB  1 
ATOM   10994 C CG  . GLU C 3 624 ? 200.643 187.540 106.452 1.00 371.52 ? 668 GLU C CG  1 
ATOM   10995 C CD  . GLU C 3 624 ? 199.874 187.472 107.757 1.00 371.52 ? 668 GLU C CD  1 
ATOM   10996 O OE1 . GLU C 3 624 ? 200.333 188.072 108.751 1.00 371.52 ? 668 GLU C OE1 1 
ATOM   10997 O OE2 . GLU C 3 624 ? 198.811 186.816 107.788 1.00 371.52 ? 668 GLU C OE2 1 
ATOM   10998 N N   . PRO C 3 625 ? 200.049 190.764 104.470 1.00 381.57 ? 669 PRO C N   1 
ATOM   10999 C CA  . PRO C 3 625 ? 200.482 192.102 104.893 1.00 381.57 ? 669 PRO C CA  1 
ATOM   11000 C C   . PRO C 3 625 ? 201.068 192.079 106.297 1.00 381.57 ? 669 PRO C C   1 
ATOM   11001 O O   . PRO C 3 625 ? 200.597 191.356 107.178 1.00 381.57 ? 669 PRO C O   1 
ATOM   11002 C CB  . PRO C 3 625 ? 199.194 192.934 104.830 1.00 381.57 ? 669 PRO C CB  1 
ATOM   11003 C CG  . PRO C 3 625 ? 198.075 191.937 104.742 1.00 381.57 ? 669 PRO C CG  1 
ATOM   11004 C CD  . PRO C 3 625 ? 198.645 190.761 104.025 1.00 381.57 ? 669 PRO C CD  1 
ATOM   11005 N N   . CYS C 3 626 ? 202.110 192.882 106.495 1.00 374.46 ? 670 CYS C N   1 
ATOM   11006 C CA  . CYS C 3 626 ? 202.828 192.895 107.761 1.00 374.46 ? 670 CYS C CA  1 
ATOM   11007 C C   . CYS C 3 626 ? 201.967 193.450 108.890 1.00 374.46 ? 670 CYS C C   1 
ATOM   11008 O O   . CYS C 3 626 ? 201.015 194.205 108.670 1.00 374.46 ? 670 CYS C O   1 
ATOM   11009 C CB  . CYS C 3 626 ? 204.100 193.735 107.649 1.00 374.46 ? 670 CYS C CB  1 
ATOM   11010 S SG  . CYS C 3 626 ? 205.374 193.127 106.523 1.00 374.46 ? 670 CYS C SG  1 
ATOM   11011 N N   . LEU C 3 627 ? 202.319 193.063 110.114 1.00 336.11 ? 671 LEU C N   1 
ATOM   11012 C CA  . LEU C 3 627 ? 201.796 193.704 111.319 1.00 336.11 ? 671 LEU C CA  1 
ATOM   11013 C C   . LEU C 3 627 ? 202.794 194.768 111.773 1.00 336.11 ? 671 LEU C C   1 
ATOM   11014 O O   . LEU C 3 627 ? 203.494 194.635 112.779 1.00 336.11 ? 671 LEU C O   1 
ATOM   11015 C CB  . LEU C 3 627 ? 201.536 192.665 112.405 1.00 336.11 ? 671 LEU C CB  1 
ATOM   11016 C CG  . LEU C 3 627 ? 200.499 191.587 112.088 1.00 336.11 ? 671 LEU C CG  1 
ATOM   11017 C CD1 . LEU C 3 627 ? 200.321 190.651 113.273 1.00 336.11 ? 671 LEU C CD1 1 
ATOM   11018 C CD2 . LEU C 3 627 ? 199.172 192.218 111.695 1.00 336.11 ? 671 LEU C CD2 1 
ATOM   11019 N N   . MET C 3 628 ? 202.846 195.841 110.987 1.00 340.25 ? 672 MET C N   1 
ATOM   11020 C CA  . MET C 3 628 ? 203.900 196.838 111.120 1.00 340.25 ? 672 MET C CA  1 
ATOM   11021 C C   . MET C 3 628 ? 203.842 197.531 112.476 1.00 340.25 ? 672 MET C C   1 
ATOM   11022 O O   . MET C 3 628 ? 202.772 197.941 112.936 1.00 340.25 ? 672 MET C O   1 
ATOM   11023 C CB  . MET C 3 628 ? 203.788 197.867 109.997 1.00 340.25 ? 672 MET C CB  1 
ATOM   11024 C CG  . MET C 3 628 ? 203.950 197.278 108.605 1.00 340.25 ? 672 MET C CG  1 
ATOM   11025 S SD  . MET C 3 628 ? 202.760 197.938 107.422 1.00 340.25 ? 672 MET C SD  1 
ATOM   11026 C CE  . MET C 3 628 ? 201.216 197.493 108.213 1.00 340.25 ? 672 MET C CE  1 
ATOM   11027 N N   . ASP C 3 629 ? 205.004 197.657 113.113 1.00 325.51 ? 673 ASP C N   1 
ATOM   11028 C CA  . ASP C 3 629 ? 205.152 198.377 114.367 1.00 325.51 ? 673 ASP C CA  1 
ATOM   11029 C C   . ASP C 3 629 ? 206.277 199.392 114.222 1.00 325.51 ? 673 ASP C C   1 
ATOM   11030 O O   . ASP C 3 629 ? 207.237 199.175 113.477 1.00 325.51 ? 673 ASP C O   1 
ATOM   11031 C CB  . ASP C 3 629 ? 205.446 197.424 115.534 1.00 325.51 ? 673 ASP C CB  1 
ATOM   11032 C CG  . ASP C 3 629 ? 205.314 198.099 116.886 1.00 325.51 ? 673 ASP C CG  1 
ATOM   11033 O OD1 . ASP C 3 629 ? 204.770 199.221 116.941 1.00 325.51 ? 673 ASP C OD1 1 
ATOM   11034 O OD2 . ASP C 3 629 ? 205.757 197.507 117.893 1.00 325.51 ? 673 ASP C OD2 1 
ATOM   11035 N N   . TRP C 3 630 ? 206.151 200.505 114.940 1.00 327.67 ? 674 TRP C N   1 
ATOM   11036 C CA  . TRP C 3 630 ? 207.111 201.594 114.847 1.00 327.67 ? 674 TRP C CA  1 
ATOM   11037 C C   . TRP C 3 630 ? 207.422 202.113 116.243 1.00 327.67 ? 674 TRP C C   1 
ATOM   11038 O O   . TRP C 3 630 ? 206.803 201.715 117.234 1.00 327.67 ? 674 TRP C O   1 
ATOM   11039 C CB  . TRP C 3 630 ? 206.587 202.728 113.956 1.00 327.67 ? 674 TRP C CB  1 
ATOM   11040 C CG  . TRP C 3 630 ? 205.387 203.422 114.521 1.00 327.67 ? 674 TRP C CG  1 
ATOM   11041 C CD1 . TRP C 3 630 ? 205.366 204.618 115.177 1.00 327.67 ? 674 TRP C CD1 1 
ATOM   11042 C CD2 . TRP C 3 630 ? 204.031 202.959 114.485 1.00 327.67 ? 674 TRP C CD2 1 
ATOM   11043 N NE1 . TRP C 3 630 ? 204.081 204.930 115.549 1.00 327.67 ? 674 TRP C NE1 1 
ATOM   11044 C CE2 . TRP C 3 630 ? 203.243 203.928 115.136 1.00 327.67 ? 674 TRP C CE2 1 
ATOM   11045 C CE3 . TRP C 3 630 ? 203.407 201.822 113.963 1.00 327.67 ? 674 TRP C CE3 1 
ATOM   11046 C CZ2 . TRP C 3 630 ? 201.864 203.794 115.280 1.00 327.67 ? 674 TRP C CZ2 1 
ATOM   11047 C CZ3 . TRP C 3 630 ? 202.038 201.690 114.108 1.00 327.67 ? 674 TRP C CZ3 1 
ATOM   11048 C CH2 . TRP C 3 630 ? 201.282 202.671 114.761 1.00 327.67 ? 674 TRP C CH2 1 
ATOM   11049 N N   . ARG C 3 631 ? 208.397 203.017 116.311 1.00 327.89 ? 675 ARG C N   1 
ATOM   11050 C CA  . ARG C 3 631 ? 208.804 203.617 117.580 1.00 327.89 ? 675 ARG C CA  1 
ATOM   11051 C C   . ARG C 3 631 ? 209.524 204.920 117.280 1.00 327.89 ? 675 ARG C C   1 
ATOM   11052 O O   . ARG C 3 631 ? 210.521 204.920 116.550 1.00 327.89 ? 675 ARG C O   1 
ATOM   11053 C CB  . ARG C 3 631 ? 209.703 202.668 118.372 1.00 327.89 ? 675 ARG C CB  1 
ATOM   11054 C CG  . ARG C 3 631 ? 210.268 203.269 119.648 1.00 327.89 ? 675 ARG C CG  1 
ATOM   11055 C CD  . ARG C 3 631 ? 211.204 202.296 120.346 1.00 327.89 ? 675 ARG C CD  1 
ATOM   11056 N NE  . ARG C 3 631 ? 211.802 202.877 121.544 1.00 327.89 ? 675 ARG C NE  1 
ATOM   11057 C CZ  . ARG C 3 631 ? 212.683 202.251 122.318 1.00 327.89 ? 675 ARG C CZ  1 
ATOM   11058 N NH1 . ARG C 3 631 ? 213.071 201.018 122.020 1.00 327.89 ? 675 ARG C NH1 1 
ATOM   11059 N NH2 . ARG C 3 631 ? 213.176 202.856 123.390 1.00 327.89 ? 675 ARG C NH2 1 
ATOM   11060 N N   . LYS C 3 632 ? 209.026 206.022 117.835 1.00 345.89 ? 676 LYS C N   1 
ATOM   11061 C CA  . LYS C 3 632 ? 209.630 207.327 117.607 1.00 345.89 ? 676 LYS C CA  1 
ATOM   11062 C C   . LYS C 3 632 ? 210.809 207.533 118.550 1.00 345.89 ? 676 LYS C C   1 
ATOM   11063 O O   . LYS C 3 632 ? 210.682 207.354 119.765 1.00 345.89 ? 676 LYS C O   1 
ATOM   11064 C CB  . LYS C 3 632 ? 208.595 208.434 117.799 1.00 345.89 ? 676 LYS C CB  1 
ATOM   11065 C CG  . LYS C 3 632 ? 207.561 208.513 116.688 1.00 345.89 ? 676 LYS C CG  1 
ATOM   11066 C CD  . LYS C 3 632 ? 206.698 209.757 116.820 1.00 345.89 ? 676 LYS C CD  1 
ATOM   11067 C CE  . LYS C 3 632 ? 205.749 209.898 115.641 1.00 345.89 ? 676 LYS C CE  1 
ATOM   11068 N NZ  . LYS C 3 632 ? 204.917 211.128 115.740 1.00 345.89 ? 676 LYS C NZ  1 
ATOM   11069 N N   . VAL C 3 633 ? 211.952 207.908 117.987 1.00 387.48 ? 677 VAL C N   1 
ATOM   11070 C CA  . VAL C 3 633 ? 213.178 208.141 118.740 1.00 387.48 ? 677 VAL C CA  1 
ATOM   11071 C C   . VAL C 3 633 ? 213.596 209.586 118.509 1.00 387.48 ? 677 VAL C C   1 
ATOM   11072 O O   . VAL C 3 633 ? 213.651 210.026 117.360 1.00 387.48 ? 677 VAL C O   1 
ATOM   11073 C CB  . VAL C 3 633 ? 214.313 207.186 118.329 1.00 387.48 ? 677 VAL C CB  1 
ATOM   11074 C CG1 . VAL C 3 633 ? 215.442 207.235 119.346 1.00 387.48 ? 677 VAL C CG1 1 
ATOM   11075 C CG2 . VAL C 3 633 ? 213.786 205.766 118.177 1.00 387.48 ? 677 VAL C CG2 1 
ATOM   11076 N N   . PRO C 3 634 ? 213.893 210.355 119.556 1.00 394.13 ? 678 PRO C N   1 
ATOM   11077 C CA  . PRO C 3 634 ? 214.312 211.749 119.362 1.00 394.13 ? 678 PRO C CA  1 
ATOM   11078 C C   . PRO C 3 634 ? 215.622 211.842 118.594 1.00 394.13 ? 678 PRO C C   1 
ATOM   11079 O O   . PRO C 3 634 ? 216.362 210.870 118.428 1.00 394.13 ? 678 PRO C O   1 
ATOM   11080 C CB  . PRO C 3 634 ? 214.459 212.283 120.792 1.00 394.13 ? 678 PRO C CB  1 
ATOM   11081 C CG  . PRO C 3 634 ? 213.633 211.361 121.633 1.00 394.13 ? 678 PRO C CG  1 
ATOM   11082 C CD  . PRO C 3 634 ? 213.742 210.017 120.981 1.00 394.13 ? 678 PRO C CD  1 
ATOM   11083 N N   . SER C 3 635 ? 215.909 213.056 118.118 1.00 397.02 ? 679 SER C N   1 
ATOM   11084 C CA  . SER C 3 635 ? 217.087 213.279 117.288 1.00 397.02 ? 679 SER C CA  1 
ATOM   11085 C C   . SER C 3 635 ? 218.385 213.235 118.083 1.00 397.02 ? 679 SER C C   1 
ATOM   11086 O O   . SER C 3 635 ? 219.454 213.063 117.487 1.00 397.02 ? 679 SER C O   1 
ATOM   11087 C CB  . SER C 3 635 ? 216.971 214.620 116.562 1.00 397.02 ? 679 SER C CB  1 
ATOM   11088 O OG  . SER C 3 635 ? 218.094 214.847 115.728 1.00 397.02 ? 679 SER C OG  1 
ATOM   11089 N N   . ASN C 3 636 ? 218.323 213.386 119.406 1.00 392.87 ? 680 ASN C N   1 
ATOM   11090 C CA  . ASN C 3 636 ? 219.530 213.384 120.223 1.00 392.87 ? 680 ASN C CA  1 
ATOM   11091 C C   . ASN C 3 636 ? 220.075 211.985 120.482 1.00 392.87 ? 680 ASN C C   1 
ATOM   11092 O O   . ASN C 3 636 ? 221.171 211.861 121.038 1.00 392.87 ? 680 ASN C O   1 
ATOM   11093 C CB  . ASN C 3 636 ? 219.265 214.083 121.559 1.00 392.87 ? 680 ASN C CB  1 
ATOM   11094 C CG  . ASN C 3 636 ? 218.361 213.277 122.470 1.00 392.87 ? 680 ASN C CG  1 
ATOM   11095 O OD1 . ASN C 3 636 ? 217.486 212.545 122.008 1.00 392.87 ? 680 ASN C OD1 1 
ATOM   11096 N ND2 . ASN C 3 636 ? 218.570 213.406 123.775 1.00 392.87 ? 680 ASN C ND2 1 
ATOM   11097 N N   . SER C 3 637 ? 219.347 210.941 120.099 1.00 403.47 ? 681 SER C N   1 
ATOM   11098 C CA  . SER C 3 637 ? 219.774 209.567 120.313 1.00 403.47 ? 681 SER C CA  1 
ATOM   11099 C C   . SER C 3 637 ? 220.373 208.997 119.034 1.00 403.47 ? 681 SER C C   1 
ATOM   11100 O O   . SER C 3 637 ? 219.897 209.281 117.931 1.00 403.47 ? 681 SER C O   1 
ATOM   11101 C CB  . SER C 3 637 ? 218.602 208.697 120.774 1.00 403.47 ? 681 SER C CB  1 
ATOM   11102 O OG  . SER C 3 637 ? 217.931 209.288 121.873 1.00 403.47 ? 681 SER C OG  1 
ATOM   11103 N N   . THR C 3 638 ? 221.422 208.188 119.190 1.00 404.02 ? 682 THR C N   1 
ATOM   11104 C CA  . THR C 3 638 ? 222.089 207.553 118.063 1.00 404.02 ? 682 THR C CA  1 
ATOM   11105 C C   . THR C 3 638 ? 222.109 206.034 118.139 1.00 404.02 ? 682 THR C C   1 
ATOM   11106 O O   . THR C 3 638 ? 222.428 205.389 117.133 1.00 404.02 ? 682 THR C O   1 
ATOM   11107 C CB  . THR C 3 638 ? 223.535 208.058 117.937 1.00 404.02 ? 682 THR C CB  1 
ATOM   11108 O OG1 . THR C 3 638 ? 224.206 207.338 116.896 1.00 404.02 ? 682 THR C OG1 1 
ATOM   11109 C CG2 . THR C 3 638 ? 224.284 207.860 119.246 1.00 404.02 ? 682 THR C CG2 1 
ATOM   11110 N N   . GLU C 3 639 ? 221.783 205.444 119.287 1.00 404.64 ? 683 GLU C N   1 
ATOM   11111 C CA  . GLU C 3 639 ? 221.786 203.993 119.436 1.00 404.64 ? 683 GLU C CA  1 
ATOM   11112 C C   . GLU C 3 639 ? 220.624 203.596 120.331 1.00 404.64 ? 683 GLU C C   1 
ATOM   11113 O O   . GLU C 3 639 ? 220.545 204.044 121.479 1.00 404.64 ? 683 GLU C O   1 
ATOM   11114 C CB  . GLU C 3 639 ? 223.112 203.502 120.023 1.00 404.64 ? 683 GLU C CB  1 
ATOM   11115 C CG  . GLU C 3 639 ? 223.539 202.129 119.532 1.00 404.64 ? 683 GLU C CG  1 
ATOM   11116 C CD  . GLU C 3 639 ? 222.653 201.019 120.059 1.00 404.64 ? 683 GLU C CD  1 
ATOM   11117 O OE1 . GLU C 3 639 ? 222.271 201.075 121.247 1.00 404.64 ? 683 GLU C OE1 1 
ATOM   11118 O OE2 . GLU C 3 639 ? 222.336 200.092 119.285 1.00 404.64 ? 683 GLU C OE2 1 
ATOM   11119 N N   . THR C 3 640 ? 219.728 202.762 119.807 1.00 383.25 ? 684 THR C N   1 
ATOM   11120 C CA  . THR C 3 640 ? 218.566 202.300 120.551 1.00 383.25 ? 684 THR C CA  1 
ATOM   11121 C C   . THR C 3 640 ? 218.369 200.812 120.301 1.00 383.25 ? 684 THR C C   1 
ATOM   11122 O O   . THR C 3 640 ? 219.030 200.206 119.453 1.00 383.25 ? 684 THR C O   1 
ATOM   11123 C CB  . THR C 3 640 ? 217.300 203.077 120.167 1.00 383.25 ? 684 THR C CB  1 
ATOM   11124 O OG1 . THR C 3 640 ? 217.257 203.252 118.745 1.00 383.25 ? 684 THR C OG1 1 
ATOM   11125 C CG2 . THR C 3 640 ? 217.282 204.438 120.845 1.00 383.25 ? 684 THR C CG2 1 
ATOM   11126 N N   . VAL C 3 641 ? 217.446 200.222 121.058 1.00 353.96 ? 685 VAL C N   1 
ATOM   11127 C CA  . VAL C 3 641 ? 217.113 198.810 120.940 1.00 353.96 ? 685 VAL C CA  1 
ATOM   11128 C C   . VAL C 3 641 ? 215.601 198.683 120.807 1.00 353.96 ? 685 VAL C C   1 
ATOM   11129 O O   . VAL C 3 641 ? 214.843 199.540 121.272 1.00 353.96 ? 685 VAL C O   1 
ATOM   11130 C CB  . VAL C 3 641 ? 217.642 197.998 122.147 1.00 353.96 ? 685 VAL C CB  1 
ATOM   11131 C CG1 . VAL C 3 641 ? 216.901 198.381 123.423 1.00 353.96 ? 685 VAL C CG1 1 
ATOM   11132 C CG2 . VAL C 3 641 ? 217.560 196.498 121.883 1.00 353.96 ? 685 VAL C CG2 1 
ATOM   11133 N N   . ILE C 3 642 ? 215.165 197.608 120.155 1.00 334.51 ? 686 ILE C N   1 
ATOM   11134 C CA  . ILE C 3 642 ? 213.752 197.350 119.899 1.00 334.51 ? 686 ILE C CA  1 
ATOM   11135 C C   . ILE C 3 642 ? 213.304 196.216 120.810 1.00 334.51 ? 686 ILE C C   1 
ATOM   11136 O O   . ILE C 3 642 ? 213.897 195.130 120.802 1.00 334.51 ? 686 ILE C O   1 
ATOM   11137 C CB  . ILE C 3 642 ? 213.497 197.007 118.424 1.00 334.51 ? 686 ILE C CB  1 
ATOM   11138 C CG1 . ILE C 3 642 ? 213.815 198.213 117.535 1.00 334.51 ? 686 ILE C CG1 1 
ATOM   11139 C CG2 . ILE C 3 642 ? 212.061 196.546 118.223 1.00 334.51 ? 686 ILE C CG2 1 
ATOM   11140 C CD1 . ILE C 3 642 ? 213.343 198.063 116.104 1.00 334.51 ? 686 ILE C CD1 1 
ATOM   11141 N N   . GLU C 3 643 ? 212.258 196.467 121.595 1.00 324.82 ? 687 GLU C N   1 
ATOM   11142 C CA  . GLU C 3 643 ? 211.697 195.485 122.517 1.00 324.82 ? 687 GLU C CA  1 
ATOM   11143 C C   . GLU C 3 643 ? 210.297 195.120 122.039 1.00 324.82 ? 687 GLU C C   1 
ATOM   11144 O O   . GLU C 3 643 ? 209.379 195.945 122.102 1.00 324.82 ? 687 GLU C O   1 
ATOM   11145 C CB  . GLU C 3 643 ? 211.668 196.030 123.944 1.00 324.82 ? 687 GLU C CB  1 
ATOM   11146 C CG  . GLU C 3 643 ? 212.918 195.727 124.754 1.00 324.82 ? 687 GLU C CG  1 
ATOM   11147 C CD  . GLU C 3 643 ? 213.370 194.287 124.614 1.00 324.82 ? 687 GLU C CD  1 
ATOM   11148 O OE1 . GLU C 3 643 ? 214.325 194.034 123.851 1.00 324.82 ? 687 GLU C OE1 1 
ATOM   11149 O OE2 . GLU C 3 643 ? 212.771 193.408 125.268 1.00 324.82 ? 687 GLU C OE2 1 
ATOM   11150 N N   . SER C 3 644 ? 210.135 193.888 121.563 1.00 289.53 ? 688 SER C N   1 
ATOM   11151 C CA  . SER C 3 644 ? 208.844 193.411 121.091 1.00 289.53 ? 688 SER C CA  1 
ATOM   11152 C C   . SER C 3 644 ? 208.746 191.913 121.339 1.00 289.53 ? 688 SER C C   1 
ATOM   11153 O O   . SER C 3 644 ? 209.738 191.186 121.241 1.00 289.53 ? 688 SER C O   1 
ATOM   11154 C CB  . SER C 3 644 ? 208.636 193.719 119.604 1.00 289.53 ? 688 SER C CB  1 
ATOM   11155 O OG  . SER C 3 644 ? 209.794 193.406 118.849 1.00 289.53 ? 688 SER C OG  1 
ATOM   11156 N N   . ASP C 3 645 ? 207.534 191.461 121.661 1.00 264.82 ? 689 ASP C N   1 
ATOM   11157 C CA  . ASP C 3 645 ? 207.289 190.051 121.930 1.00 264.82 ? 689 ASP C CA  1 
ATOM   11158 C C   . ASP C 3 645 ? 207.119 189.219 120.665 1.00 264.82 ? 689 ASP C C   1 
ATOM   11159 O O   . ASP C 3 645 ? 207.083 187.987 120.756 1.00 264.82 ? 689 ASP C O   1 
ATOM   11160 C CB  . ASP C 3 645 ? 206.054 189.896 122.823 1.00 264.82 ? 689 ASP C CB  1 
ATOM   11161 C CG  . ASP C 3 645 ? 204.837 190.624 122.274 1.00 264.82 ? 689 ASP C CG  1 
ATOM   11162 O OD1 . ASP C 3 645 ? 203.861 190.800 123.034 1.00 264.82 ? 689 ASP C OD1 1 
ATOM   11163 O OD2 . ASP C 3 645 ? 204.855 191.031 121.093 1.00 264.82 ? 689 ASP C OD2 1 
ATOM   11164 N N   . GLU C 3 646 ? 207.014 189.853 119.497 1.00 257.15 ? 690 GLU C N   1 
ATOM   11165 C CA  . GLU C 3 646 ? 206.834 189.125 118.248 1.00 257.15 ? 690 GLU C CA  1 
ATOM   11166 C C   . GLU C 3 646 ? 208.143 188.610 117.664 1.00 257.15 ? 690 GLU C C   1 
ATOM   11167 O O   . GLU C 3 646 ? 208.110 187.871 116.674 1.00 257.15 ? 690 GLU C O   1 
ATOM   11168 C CB  . GLU C 3 646 ? 206.129 190.014 117.220 1.00 257.15 ? 690 GLU C CB  1 
ATOM   11169 C CG  . GLU C 3 646 ? 204.743 190.483 117.641 1.00 257.15 ? 690 GLU C CG  1 
ATOM   11170 C CD  . GLU C 3 646 ? 203.703 189.380 117.572 1.00 257.15 ? 690 GLU C CD  1 
ATOM   11171 O OE1 . GLU C 3 646 ? 203.695 188.506 118.464 1.00 257.15 ? 690 GLU C OE1 1 
ATOM   11172 O OE2 . GLU C 3 646 ? 202.890 189.389 116.623 1.00 257.15 ? 690 GLU C OE2 1 
ATOM   11173 N N   . PHE C 3 647 ? 209.283 188.977 118.243 1.00 264.35 ? 691 PHE C N   1 
ATOM   11174 C CA  . PHE C 3 647 ? 210.569 188.512 117.740 1.00 264.35 ? 691 PHE C CA  1 
ATOM   11175 C C   . PHE C 3 647 ? 210.763 187.042 118.095 1.00 264.35 ? 691 PHE C C   1 
ATOM   11176 O O   . PHE C 3 647 ? 210.825 186.683 119.276 1.00 264.35 ? 691 PHE C O   1 
ATOM   11177 C CB  . PHE C 3 647 ? 211.701 189.359 118.317 1.00 264.35 ? 691 PHE C CB  1 
ATOM   11178 C CG  . PHE C 3 647 ? 211.848 190.702 117.659 1.00 264.35 ? 691 PHE C CG  1 
ATOM   11179 C CD1 . PHE C 3 647 ? 211.252 190.958 116.435 1.00 264.35 ? 691 PHE C CD1 1 
ATOM   11180 C CD2 . PHE C 3 647 ? 212.586 191.706 118.263 1.00 264.35 ? 691 PHE C CD2 1 
ATOM   11181 C CE1 . PHE C 3 647 ? 211.387 192.192 115.827 1.00 264.35 ? 691 PHE C CE1 1 
ATOM   11182 C CE2 . PHE C 3 647 ? 212.724 192.942 117.659 1.00 264.35 ? 691 PHE C CE2 1 
ATOM   11183 C CZ  . PHE C 3 647 ? 212.124 193.185 116.440 1.00 264.35 ? 691 PHE C CZ  1 
ATOM   11184 N N   . ARG C 3 648 ? 210.858 186.194 117.073 1.00 250.33 ? 692 ARG C N   1 
ATOM   11185 C CA  . ARG C 3 648 ? 211.024 184.764 117.256 1.00 250.33 ? 692 ARG C CA  1 
ATOM   11186 C C   . ARG C 3 648 ? 212.289 184.282 116.555 1.00 250.33 ? 692 ARG C C   1 
ATOM   11187 O O   . ARG C 3 648 ? 212.689 184.846 115.530 1.00 250.33 ? 692 ARG C O   1 
ATOM   11188 C CB  . ARG C 3 648 ? 209.815 183.994 116.711 1.00 250.33 ? 692 ARG C CB  1 
ATOM   11189 C CG  . ARG C 3 648 ? 208.481 184.455 117.275 1.00 250.33 ? 692 ARG C CG  1 
ATOM   11190 C CD  . ARG C 3 648 ? 207.319 183.739 116.605 1.00 250.33 ? 692 ARG C CD  1 
ATOM   11191 N NE  . ARG C 3 648 ? 206.030 184.190 117.119 1.00 250.33 ? 692 ARG C NE  1 
ATOM   11192 C CZ  . ARG C 3 648 ? 204.855 183.738 116.692 1.00 250.33 ? 692 ARG C CZ  1 
ATOM   11193 N NH1 . ARG C 3 648 ? 204.804 182.817 115.739 1.00 250.33 ? 692 ARG C NH1 1 
ATOM   11194 N NH2 . ARG C 3 648 ? 203.731 184.206 117.217 1.00 250.33 ? 692 ARG C NH2 1 
ATOM   11195 N N   . PRO C 3 649 ? 212.945 183.251 117.086 1.00 240.88 ? 693 PRO C N   1 
ATOM   11196 C CA  . PRO C 3 649 ? 214.156 182.738 116.434 1.00 240.88 ? 693 PRO C CA  1 
ATOM   11197 C C   . PRO C 3 649 ? 213.845 182.136 115.073 1.00 240.88 ? 693 PRO C C   1 
ATOM   11198 O O   . PRO C 3 649 ? 212.846 181.436 114.894 1.00 240.88 ? 693 PRO C O   1 
ATOM   11199 C CB  . PRO C 3 649 ? 214.665 181.672 117.414 1.00 240.88 ? 693 PRO C CB  1 
ATOM   11200 C CG  . PRO C 3 649 ? 214.015 182.003 118.722 1.00 240.88 ? 693 PRO C CG  1 
ATOM   11201 C CD  . PRO C 3 649 ? 212.680 182.579 118.368 1.00 240.88 ? 693 PRO C CD  1 
ATOM   11202 N N   . GLY C 3 650 ? 214.718 182.419 114.109 1.00 234.62 ? 694 GLY C N   1 
ATOM   11203 C CA  . GLY C 3 650 ? 214.553 181.911 112.763 1.00 234.62 ? 694 GLY C CA  1 
ATOM   11204 C C   . GLY C 3 650 ? 213.659 182.735 111.866 1.00 234.62 ? 694 GLY C C   1 
ATOM   11205 O O   . GLY C 3 650 ? 213.366 182.302 110.746 1.00 234.62 ? 694 GLY C O   1 
ATOM   11206 N N   . ILE C 3 651 ? 213.216 183.907 112.315 1.00 248.99 ? 695 ILE C N   1 
ATOM   11207 C CA  . ILE C 3 651 ? 212.350 184.783 111.535 1.00 248.99 ? 695 ILE C CA  1 
ATOM   11208 C C   . ILE C 3 651 ? 213.107 186.071 111.246 1.00 248.99 ? 695 ILE C C   1 
ATOM   11209 O O   . ILE C 3 651 ? 213.617 186.718 112.168 1.00 248.99 ? 695 ILE C O   1 
ATOM   11210 C CB  . ILE C 3 651 ? 211.029 185.076 112.268 1.00 248.99 ? 695 ILE C CB  1 
ATOM   11211 C CG1 . ILE C 3 651 ? 210.248 183.779 112.495 1.00 248.99 ? 695 ILE C CG1 1 
ATOM   11212 C CG2 . ILE C 3 651 ? 210.194 186.073 111.481 1.00 248.99 ? 695 ILE C CG2 1 
ATOM   11213 C CD1 . ILE C 3 651 ? 208.885 183.987 113.118 1.00 248.99 ? 695 ILE C CD1 1 
ATOM   11214 N N   . ARG C 3 652 ? 213.179 186.438 109.970 1.00 263.83 ? 696 ARG C N   1 
ATOM   11215 C CA  . ARG C 3 652 ? 213.884 187.639 109.547 1.00 263.83 ? 696 ARG C CA  1 
ATOM   11216 C C   . ARG C 3 652 ? 212.946 188.838 109.564 1.00 263.83 ? 696 ARG C C   1 
ATOM   11217 O O   . ARG C 3 652 ? 211.803 188.757 109.104 1.00 263.83 ? 696 ARG C O   1 
ATOM   11218 C CB  . ARG C 3 652 ? 214.471 187.454 108.146 1.00 263.83 ? 696 ARG C CB  1 
ATOM   11219 C CG  . ARG C 3 652 ? 215.226 188.664 107.621 1.00 263.83 ? 696 ARG C CG  1 
ATOM   11220 C CD  . ARG C 3 652 ? 215.698 188.440 106.194 1.00 263.83 ? 696 ARG C CD  1 
ATOM   11221 N NE  . ARG C 3 652 ? 214.585 188.175 105.287 1.00 263.83 ? 696 ARG C NE  1 
ATOM   11222 C CZ  . ARG C 3 652 ? 214.723 187.909 103.993 1.00 263.83 ? 696 ARG C CZ  1 
ATOM   11223 N NH1 . ARG C 3 652 ? 215.930 187.870 103.447 1.00 263.83 ? 696 ARG C NH1 1 
ATOM   11224 N NH2 . ARG C 3 652 ? 213.653 187.680 103.243 1.00 263.83 ? 696 ARG C NH2 1 
ATOM   11225 N N   . TYR C 3 653 ? 213.437 189.953 110.099 1.00 274.51 ? 697 TYR C N   1 
ATOM   11226 C CA  . TYR C 3 653 ? 212.678 191.193 110.186 1.00 274.51 ? 697 TYR C CA  1 
ATOM   11227 C C   . TYR C 3 653 ? 213.442 192.298 109.471 1.00 274.51 ? 697 TYR C C   1 
ATOM   11228 O O   . TYR C 3 653 ? 214.647 192.465 109.688 1.00 274.51 ? 697 TYR C O   1 
ATOM   11229 C CB  . TYR C 3 653 ? 212.423 191.583 111.645 1.00 274.51 ? 697 TYR C CB  1 
ATOM   11230 C CG  . TYR C 3 653 ? 211.679 190.535 112.442 1.00 274.51 ? 697 TYR C CG  1 
ATOM   11231 C CD1 . TYR C 3 653 ? 210.290 190.512 112.470 1.00 274.51 ? 697 TYR C CD1 1 
ATOM   11232 C CD2 . TYR C 3 653 ? 212.364 189.570 113.168 1.00 274.51 ? 697 TYR C CD2 1 
ATOM   11233 C CE1 . TYR C 3 653 ? 209.606 189.557 113.197 1.00 274.51 ? 697 TYR C CE1 1 
ATOM   11234 C CE2 . TYR C 3 653 ? 211.688 188.610 113.898 1.00 274.51 ? 697 TYR C CE2 1 
ATOM   11235 C CZ  . TYR C 3 653 ? 210.309 188.609 113.909 1.00 274.51 ? 697 TYR C CZ  1 
ATOM   11236 O OH  . TYR C 3 653 ? 209.631 187.656 114.634 1.00 274.51 ? 697 TYR C OH  1 
ATOM   11237 N N   . ASN C 3 654 ? 212.742 193.046 108.623 1.00 281.75 ? 698 ASN C N   1 
ATOM   11238 C CA  . ASN C 3 654 ? 213.342 194.145 107.877 1.00 281.75 ? 698 ASN C CA  1 
ATOM   11239 C C   . ASN C 3 654 ? 213.156 195.441 108.657 1.00 281.75 ? 698 ASN C C   1 
ATOM   11240 O O   . ASN C 3 654 ? 212.024 195.832 108.961 1.00 281.75 ? 698 ASN C O   1 
ATOM   11241 C CB  . ASN C 3 654 ? 212.719 194.261 106.487 1.00 281.75 ? 698 ASN C CB  1 
ATOM   11242 C CG  . ASN C 3 654 ? 212.726 192.947 105.733 1.00 281.75 ? 698 ASN C CG  1 
ATOM   11243 O OD1 . ASN C 3 654 ? 213.433 192.009 106.103 1.00 281.75 ? 698 ASN C OD1 1 
ATOM   11244 N ND2 . ASN C 3 654 ? 211.938 192.873 104.666 1.00 281.75 ? 698 ASN C ND2 1 
ATOM   11245 N N   . PHE C 3 655 ? 214.264 196.105 108.975 1.00 289.94 ? 699 PHE C N   1 
ATOM   11246 C CA  . PHE C 3 655 ? 214.252 197.350 109.730 1.00 289.94 ? 699 PHE C CA  1 
ATOM   11247 C C   . PHE C 3 655 ? 214.530 198.515 108.790 1.00 289.94 ? 699 PHE C C   1 
ATOM   11248 O O   . PHE C 3 655 ? 215.499 198.483 108.024 1.00 289.94 ? 699 PHE C O   1 
ATOM   11249 C CB  . PHE C 3 655 ? 215.287 197.317 110.857 1.00 289.94 ? 699 PHE C CB  1 
ATOM   11250 C CG  . PHE C 3 655 ? 215.094 196.183 111.823 1.00 289.94 ? 699 PHE C CG  1 
ATOM   11251 C CD1 . PHE C 3 655 ? 214.245 196.318 112.909 1.00 289.94 ? 699 PHE C CD1 1 
ATOM   11252 C CD2 . PHE C 3 655 ? 215.759 194.982 111.644 1.00 289.94 ? 699 PHE C CD2 1 
ATOM   11253 C CE1 . PHE C 3 655 ? 214.064 195.277 113.799 1.00 289.94 ? 699 PHE C CE1 1 
ATOM   11254 C CE2 . PHE C 3 655 ? 215.582 193.936 112.531 1.00 289.94 ? 699 PHE C CE2 1 
ATOM   11255 C CZ  . PHE C 3 655 ? 214.734 194.085 113.610 1.00 289.94 ? 699 PHE C CZ  1 
ATOM   11256 N N   . PHE C 3 656 ? 213.680 199.537 108.851 1.00 304.38 ? 700 PHE C N   1 
ATOM   11257 C CA  . PHE C 3 656 ? 213.798 200.719 108.008 1.00 304.38 ? 700 PHE C CA  1 
ATOM   11258 C C   . PHE C 3 656 ? 213.960 201.949 108.887 1.00 304.38 ? 700 PHE C C   1 
ATOM   11259 O O   . PHE C 3 656 ? 213.145 202.188 109.783 1.00 304.38 ? 700 PHE C O   1 
ATOM   11260 C CB  . PHE C 3 656 ? 212.574 200.873 107.099 1.00 304.38 ? 700 PHE C CB  1 
ATOM   11261 C CG  . PHE C 3 656 ? 212.357 199.713 106.170 1.00 304.38 ? 700 PHE C CG  1 
ATOM   11262 C CD1 . PHE C 3 656 ? 212.948 199.690 104.918 1.00 304.38 ? 700 PHE C CD1 1 
ATOM   11263 C CD2 . PHE C 3 656 ? 211.560 198.645 106.549 1.00 304.38 ? 700 PHE C CD2 1 
ATOM   11264 C CE1 . PHE C 3 656 ? 212.750 198.624 104.060 1.00 304.38 ? 700 PHE C CE1 1 
ATOM   11265 C CE2 . PHE C 3 656 ? 211.358 197.576 105.696 1.00 304.38 ? 700 PHE C CE2 1 
ATOM   11266 C CZ  . PHE C 3 656 ? 211.953 197.566 104.450 1.00 304.38 ? 700 PHE C CZ  1 
ATOM   11267 N N   . LEU C 3 657 ? 215.010 202.725 108.628 1.00 314.70 ? 701 LEU C N   1 
ATOM   11268 C CA  . LEU C 3 657 ? 215.296 203.942 109.377 1.00 314.70 ? 701 LEU C CA  1 
ATOM   11269 C C   . LEU C 3 657 ? 214.949 205.150 108.516 1.00 314.70 ? 701 LEU C C   1 
ATOM   11270 O O   . LEU C 3 657 ? 215.491 205.311 107.418 1.00 314.70 ? 701 LEU C O   1 
ATOM   11271 C CB  . LEU C 3 657 ? 216.764 203.988 109.802 1.00 314.70 ? 701 LEU C CB  1 
ATOM   11272 C CG  . LEU C 3 657 ? 217.259 205.311 110.389 1.00 314.70 ? 701 LEU C CG  1 
ATOM   11273 C CD1 . LEU C 3 657 ? 216.474 205.676 111.640 1.00 314.70 ? 701 LEU C CD1 1 
ATOM   11274 C CD2 . LEU C 3 657 ? 218.748 205.240 110.687 1.00 314.70 ? 701 LEU C CD2 1 
ATOM   11275 N N   . TYR C 3 658 ? 214.050 205.993 109.016 1.00 337.02 ? 702 TYR C N   1 
ATOM   11276 C CA  . TYR C 3 658 ? 213.616 207.189 108.312 1.00 337.02 ? 702 TYR C CA  1 
ATOM   11277 C C   . TYR C 3 658 ? 214.203 208.430 108.972 1.00 337.02 ? 702 TYR C C   1 
ATOM   11278 O O   . TYR C 3 658 ? 214.426 208.464 110.186 1.00 337.02 ? 702 TYR C O   1 
ATOM   11279 C CB  . TYR C 3 658 ? 212.087 207.286 108.283 1.00 337.02 ? 702 TYR C CB  1 
ATOM   11280 C CG  . TYR C 3 658 ? 211.434 206.337 107.303 1.00 337.02 ? 702 TYR C CG  1 
ATOM   11281 C CD1 . TYR C 3 658 ? 211.079 206.760 106.029 1.00 337.02 ? 702 TYR C CD1 1 
ATOM   11282 C CD2 . TYR C 3 658 ? 211.175 205.018 107.652 1.00 337.02 ? 702 TYR C CD2 1 
ATOM   11283 C CE1 . TYR C 3 658 ? 210.483 205.897 105.129 1.00 337.02 ? 702 TYR C CE1 1 
ATOM   11284 C CE2 . TYR C 3 658 ? 210.579 204.147 106.759 1.00 337.02 ? 702 TYR C CE2 1 
ATOM   11285 C CZ  . TYR C 3 658 ? 210.235 204.592 105.500 1.00 337.02 ? 702 TYR C CZ  1 
ATOM   11286 O OH  . TYR C 3 658 ? 209.642 203.729 104.608 1.00 337.02 ? 702 TYR C OH  1 
ATOM   11287 N N   . GLY C 3 659 ? 214.451 209.452 108.158 1.00 351.00 ? 703 GLY C N   1 
ATOM   11288 C CA  . GLY C 3 659 ? 215.035 210.700 108.619 1.00 351.00 ? 703 GLY C CA  1 
ATOM   11289 C C   . GLY C 3 659 ? 214.058 211.853 108.447 1.00 351.00 ? 703 GLY C C   1 
ATOM   11290 O O   . GLY C 3 659 ? 213.429 211.994 107.397 1.00 351.00 ? 703 GLY C O   1 
ATOM   11291 N N   . CYS C 3 660 ? 213.953 212.673 109.491 1.00 367.86 ? 704 CYS C N   1 
ATOM   11292 C CA  . CYS C 3 660 ? 213.033 213.810 109.516 1.00 367.86 ? 704 CYS C CA  1 
ATOM   11293 C C   . CYS C 3 660 ? 213.778 215.046 109.030 1.00 367.86 ? 704 CYS C C   1 
ATOM   11294 O O   . CYS C 3 660 ? 214.296 215.836 109.820 1.00 367.86 ? 704 CYS C O   1 
ATOM   11295 C CB  . CYS C 3 660 ? 212.474 214.010 110.918 1.00 367.86 ? 704 CYS C CB  1 
ATOM   11296 S SG  . CYS C 3 660 ? 211.029 215.083 111.030 1.00 367.86 ? 704 CYS C SG  1 
ATOM   11297 N N   . ARG C 3 661 ? 213.822 215.226 107.712 1.00 339.92 ? 705 ARG C N   1 
ATOM   11298 C CA  . ARG C 3 661 ? 214.551 216.329 107.092 1.00 339.92 ? 705 ARG C CA  1 
ATOM   11299 C C   . ARG C 3 661 ? 213.576 217.182 106.291 1.00 339.92 ? 705 ARG C C   1 
ATOM   11300 O O   . ARG C 3 661 ? 213.028 216.725 105.282 1.00 339.92 ? 705 ARG C O   1 
ATOM   11301 C CB  . ARG C 3 661 ? 215.680 215.808 106.204 1.00 339.92 ? 705 ARG C CB  1 
ATOM   11302 C CG  . ARG C 3 661 ? 216.527 216.904 105.578 1.00 339.92 ? 705 ARG C CG  1 
ATOM   11303 C CD  . ARG C 3 661 ? 217.664 216.325 104.752 1.00 339.92 ? 705 ARG C CD  1 
ATOM   11304 N NE  . ARG C 3 661 ? 218.509 217.370 104.181 1.00 339.92 ? 705 ARG C NE  1 
ATOM   11305 C CZ  . ARG C 3 661 ? 219.588 217.138 103.442 1.00 339.92 ? 705 ARG C CZ  1 
ATOM   11306 N NH1 . ARG C 3 661 ? 219.961 215.892 103.181 1.00 339.92 ? 705 ARG C NH1 1 
ATOM   11307 N NH2 . ARG C 3 661 ? 220.297 218.151 102.963 1.00 339.92 ? 705 ARG C NH2 1 
ATOM   11308 N N   . ASN C 3 662 ? 213.366 218.419 106.745 1.00 318.91 ? 706 ASN C N   1 
ATOM   11309 C CA  . ASN C 3 662 ? 212.551 219.414 106.046 1.00 318.91 ? 706 ASN C CA  1 
ATOM   11310 C C   . ASN C 3 662 ? 211.123 218.906 105.824 1.00 318.91 ? 706 ASN C C   1 
ATOM   11311 O O   . ASN C 3 662 ? 210.657 218.743 104.694 1.00 318.91 ? 706 ASN C O   1 
ATOM   11312 C CB  . ASN C 3 662 ? 213.209 219.823 104.723 1.00 318.91 ? 706 ASN C CB  1 
ATOM   11313 C CG  . ASN C 3 662 ? 212.514 220.999 104.064 1.00 318.91 ? 706 ASN C CG  1 
ATOM   11314 O OD1 . ASN C 3 662 ? 212.534 222.116 104.581 1.00 318.91 ? 706 ASN C OD1 1 
ATOM   11315 N ND2 . ASN C 3 662 ? 211.894 220.753 102.916 1.00 318.91 ? 706 ASN C ND2 1 
ATOM   11316 N N   . GLN C 3 663 ? 210.436 218.652 106.940 1.00 317.82 ? 707 GLN C N   1 
ATOM   11317 C CA  . GLN C 3 663 ? 209.028 218.245 106.937 1.00 317.82 ? 707 GLN C CA  1 
ATOM   11318 C C   . GLN C 3 663 ? 208.796 216.988 106.102 1.00 317.82 ? 707 GLN C C   1 
ATOM   11319 O O   . GLN C 3 663 ? 207.722 216.803 105.524 1.00 317.82 ? 707 GLN C O   1 
ATOM   11320 C CB  . GLN C 3 663 ? 208.125 219.383 106.451 1.00 317.82 ? 707 GLN C CB  1 
ATOM   11321 C CG  . GLN C 3 663 ? 206.768 219.440 107.133 1.00 317.82 ? 707 GLN C CG  1 
ATOM   11322 C CD  . GLN C 3 663 ? 205.896 220.561 106.600 1.00 317.82 ? 707 GLN C CD  1 
ATOM   11323 O OE1 . GLN C 3 663 ? 206.242 221.218 105.619 1.00 317.82 ? 707 GLN C OE1 1 
ATOM   11324 N NE2 . GLN C 3 663 ? 204.759 220.785 107.248 1.00 317.82 ? 707 GLN C NE2 1 
ATOM   11325 N N   . GLY C 3 664 ? 209.798 216.117 106.029 1.00 339.63 ? 708 GLY C N   1 
ATOM   11326 C CA  . GLY C 3 664 ? 209.682 214.906 105.242 1.00 339.63 ? 708 GLY C CA  1 
ATOM   11327 C C   . GLY C 3 664 ? 210.444 213.736 105.828 1.00 339.63 ? 708 GLY C C   1 
ATOM   11328 O O   . GLY C 3 664 ? 211.549 213.907 106.352 1.00 339.63 ? 708 GLY C O   1 
ATOM   11329 N N   . TYR C 3 665 ? 209.863 212.542 105.746 1.00 359.40 ? 709 TYR C N   1 
ATOM   11330 C CA  . TYR C 3 665 ? 210.492 211.331 106.261 1.00 359.40 ? 709 TYR C CA  1 
ATOM   11331 C C   . TYR C 3 665 ? 211.277 210.672 105.133 1.00 359.40 ? 709 TYR C C   1 
ATOM   11332 O O   . TYR C 3 665 ? 210.690 210.122 104.195 1.00 359.40 ? 709 TYR C O   1 
ATOM   11333 C CB  . TYR C 3 665 ? 209.445 210.383 106.840 1.00 359.40 ? 709 TYR C CB  1 
ATOM   11334 C CG  . TYR C 3 665 ? 208.906 210.827 108.181 1.00 359.40 ? 709 TYR C CG  1 
ATOM   11335 C CD1 . TYR C 3 665 ? 209.495 210.400 109.364 1.00 359.40 ? 709 TYR C CD1 1 
ATOM   11336 C CD2 . TYR C 3 665 ? 207.813 211.679 108.264 1.00 359.40 ? 709 TYR C CD2 1 
ATOM   11337 C CE1 . TYR C 3 665 ? 209.008 210.806 110.592 1.00 359.40 ? 709 TYR C CE1 1 
ATOM   11338 C CE2 . TYR C 3 665 ? 207.319 212.091 109.487 1.00 359.40 ? 709 TYR C CE2 1 
ATOM   11339 C CZ  . TYR C 3 665 ? 207.920 211.651 110.648 1.00 359.40 ? 709 TYR C CZ  1 
ATOM   11340 O OH  . TYR C 3 665 ? 207.433 212.057 111.868 1.00 359.40 ? 709 TYR C OH  1 
ATOM   11341 N N   . GLN C 3 666 ? 212.602 210.729 105.224 1.00 360.71 ? 710 GLN C N   1 
ATOM   11342 C CA  . GLN C 3 666 ? 213.498 210.195 104.206 1.00 360.71 ? 710 GLN C CA  1 
ATOM   11343 C C   . GLN C 3 666 ? 214.179 208.949 104.756 1.00 360.71 ? 710 GLN C C   1 
ATOM   11344 O O   . GLN C 3 666 ? 214.793 208.996 105.827 1.00 360.71 ? 710 GLN C O   1 
ATOM   11345 C CB  . GLN C 3 666 ? 214.533 211.242 103.795 1.00 360.71 ? 710 GLN C CB  1 
ATOM   11346 C CG  . GLN C 3 666 ? 215.408 210.835 102.623 1.00 360.71 ? 710 GLN C CG  1 
ATOM   11347 C CD  . GLN C 3 666 ? 216.423 211.902 102.262 1.00 360.71 ? 710 GLN C CD  1 
ATOM   11348 O OE1 . GLN C 3 666 ? 216.752 212.763 103.078 1.00 360.71 ? 710 GLN C OE1 1 
ATOM   11349 N NE2 . GLN C 3 666 ? 216.924 211.851 101.033 1.00 360.71 ? 710 GLN C NE2 1 
ATOM   11350 N N   . LEU C 3 667 ? 214.074 207.843 104.023 1.00 350.49 ? 711 LEU C N   1 
ATOM   11351 C CA  . LEU C 3 667 ? 214.681 206.596 104.465 1.00 350.49 ? 711 LEU C CA  1 
ATOM   11352 C C   . LEU C 3 667 ? 216.201 206.696 104.414 1.00 350.49 ? 711 LEU C C   1 
ATOM   11353 O O   . LEU C 3 667 ? 216.773 207.292 103.497 1.00 350.49 ? 711 LEU C O   1 
ATOM   11354 C CB  . LEU C 3 667 ? 214.194 205.424 103.609 1.00 350.49 ? 711 LEU C CB  1 
ATOM   11355 C CG  . LEU C 3 667 ? 214.691 205.267 102.168 1.00 350.49 ? 711 LEU C CG  1 
ATOM   11356 C CD1 . LEU C 3 667 ? 214.452 203.846 101.685 1.00 350.49 ? 711 LEU C CD1 1 
ATOM   11357 C CD2 . LEU C 3 667 ? 214.010 206.258 101.236 1.00 350.49 ? 711 LEU C CD2 1 
ATOM   11358 N N   . LEU C 3 668 ? 216.856 206.114 105.419 1.00 330.99 ? 712 LEU C N   1 
ATOM   11359 C CA  . LEU C 3 668 ? 218.305 206.182 105.551 1.00 330.99 ? 712 LEU C CA  1 
ATOM   11360 C C   . LEU C 3 668 ? 218.963 204.814 105.414 1.00 330.99 ? 712 LEU C C   1 
ATOM   11361 O O   . LEU C 3 668 ? 219.853 204.636 104.578 1.00 330.99 ? 712 LEU C O   1 
ATOM   11362 C CB  . LEU C 3 668 ? 218.677 206.818 106.898 1.00 330.99 ? 712 LEU C CB  1 
ATOM   11363 C CG  . LEU C 3 668 ? 218.024 208.162 107.222 1.00 330.99 ? 712 LEU C CG  1 
ATOM   11364 C CD1 . LEU C 3 668 ? 218.402 208.612 108.624 1.00 330.99 ? 712 LEU C CD1 1 
ATOM   11365 C CD2 . LEU C 3 668 ? 218.413 209.212 106.193 1.00 330.99 ? 712 LEU C CD2 1 
ATOM   11366 N N   . ARG C 3 669 ? 218.547 203.838 106.219 1.00 301.79 ? 713 ARG C N   1 
ATOM   11367 C CA  . ARG C 3 669 ? 219.177 202.526 106.247 1.00 301.79 ? 713 ARG C CA  1 
ATOM   11368 C C   . ARG C 3 669 ? 218.117 201.436 106.252 1.00 301.79 ? 713 ARG C C   1 
ATOM   11369 O O   . ARG C 3 669 ? 217.090 201.558 106.927 1.00 301.79 ? 713 ARG C O   1 
ATOM   11370 C CB  . ARG C 3 669 ? 220.082 202.370 107.477 1.00 301.79 ? 713 ARG C CB  1 
ATOM   11371 C CG  . ARG C 3 669 ? 221.248 203.343 107.524 1.00 301.79 ? 713 ARG C CG  1 
ATOM   11372 C CD  . ARG C 3 669 ? 221.996 203.244 108.842 1.00 301.79 ? 713 ARG C CD  1 
ATOM   11373 N NE  . ARG C 3 669 ? 223.179 204.098 108.862 1.00 301.79 ? 713 ARG C NE  1 
ATOM   11374 C CZ  . ARG C 3 669 ? 224.393 203.700 108.496 1.00 301.79 ? 713 ARG C CZ  1 
ATOM   11375 N NH1 . ARG C 3 669 ? 224.587 202.456 108.080 1.00 301.79 ? 713 ARG C NH1 1 
ATOM   11376 N NH2 . ARG C 3 669 ? 225.413 204.545 108.545 1.00 301.79 ? 713 ARG C NH2 1 
ATOM   11377 N N   . SER C 3 670 ? 218.374 200.372 105.496 1.00 295.59 ? 714 SER C N   1 
ATOM   11378 C CA  . SER C 3 670 ? 217.524 199.186 105.467 1.00 295.59 ? 714 SER C CA  1 
ATOM   11379 C C   . SER C 3 670 ? 218.339 198.018 106.009 1.00 295.59 ? 714 SER C C   1 
ATOM   11380 O O   . SER C 3 670 ? 219.284 197.559 105.359 1.00 295.59 ? 714 SER C O   1 
ATOM   11381 C CB  . SER C 3 670 ? 217.021 198.904 104.053 1.00 295.59 ? 714 SER C CB  1 
ATOM   11382 O OG  . SER C 3 670 ? 216.090 197.835 104.047 1.00 295.59 ? 714 SER C OG  1 
ATOM   11383 N N   . MET C 3 671 ? 217.974 197.540 107.196 1.00 277.35 ? 715 MET C N   1 
ATOM   11384 C CA  . MET C 3 671 ? 218.720 196.499 107.887 1.00 277.35 ? 715 MET C CA  1 
ATOM   11385 C C   . MET C 3 671 ? 217.829 195.289 108.131 1.00 277.35 ? 715 MET C C   1 
ATOM   11386 O O   . MET C 3 671 ? 216.652 195.430 108.476 1.00 277.35 ? 715 MET C O   1 
ATOM   11387 C CB  . MET C 3 671 ? 219.276 197.014 109.219 1.00 277.35 ? 715 MET C CB  1 
ATOM   11388 C CG  . MET C 3 671 ? 220.233 198.186 109.079 1.00 277.35 ? 715 MET C CG  1 
ATOM   11389 S SD  . MET C 3 671 ? 220.638 198.948 110.662 1.00 277.35 ? 715 MET C SD  1 
ATOM   11390 C CE  . MET C 3 671 ? 219.043 199.611 111.135 1.00 277.35 ? 715 MET C CE  1 
ATOM   11391 N N   . ILE C 3 672 ? 218.401 194.100 107.949 1.00 255.94 ? 716 ILE C N   1 
ATOM   11392 C CA  . ILE C 3 672 ? 217.712 192.845 108.211 1.00 255.94 ? 716 ILE C CA  1 
ATOM   11393 C C   . ILE C 3 672 ? 218.544 192.032 109.194 1.00 255.94 ? 716 ILE C C   1 
ATOM   11394 O O   . ILE C 3 672 ? 219.762 192.197 109.303 1.00 255.94 ? 716 ILE C O   1 
ATOM   11395 C CB  . ILE C 3 672 ? 217.448 192.037 106.923 1.00 255.94 ? 716 ILE C CB  1 
ATOM   11396 C CG1 . ILE C 3 672 ? 218.766 191.563 106.307 1.00 255.94 ? 716 ILE C CG1 1 
ATOM   11397 C CG2 . ILE C 3 672 ? 216.655 192.865 105.924 1.00 255.94 ? 716 ILE C CG2 1 
ATOM   11398 C CD1 . ILE C 3 672 ? 218.590 190.629 105.131 1.00 255.94 ? 716 ILE C CD1 1 
ATOM   11399 N N   . GLY C 3 673 ? 217.869 191.148 109.915 1.00 249.46 ? 717 GLY C N   1 
ATOM   11400 C CA  . GLY C 3 673 ? 218.547 190.313 110.885 1.00 249.46 ? 717 GLY C CA  1 
ATOM   11401 C C   . GLY C 3 673 ? 217.558 189.473 111.661 1.00 249.46 ? 717 GLY C C   1 
ATOM   11402 O O   . GLY C 3 673 ? 216.345 189.523 111.436 1.00 249.46 ? 717 GLY C O   1 
ATOM   11403 N N   . TYR C 3 674 ? 218.108 188.694 112.586 1.00 246.20 ? 718 TYR C N   1 
ATOM   11404 C CA  . TYR C 3 674 ? 217.337 187.801 113.436 1.00 246.20 ? 718 TYR C CA  1 
ATOM   11405 C C   . TYR C 3 674 ? 217.518 188.195 114.897 1.00 246.20 ? 718 TYR C C   1 
ATOM   11406 O O   . TYR C 3 674 ? 218.399 188.983 115.250 1.00 246.20 ? 718 TYR C O   1 
ATOM   11407 C CB  . TYR C 3 674 ? 217.755 186.340 113.224 1.00 246.20 ? 718 TYR C CB  1 
ATOM   11408 C CG  . TYR C 3 674 ? 217.566 185.846 111.807 1.00 246.20 ? 718 TYR C CG  1 
ATOM   11409 C CD1 . TYR C 3 674 ? 216.384 185.229 111.418 1.00 246.20 ? 718 TYR C CD1 1 
ATOM   11410 C CD2 . TYR C 3 674 ? 218.570 185.994 110.859 1.00 246.20 ? 718 TYR C CD2 1 
ATOM   11411 C CE1 . TYR C 3 674 ? 216.206 184.776 110.125 1.00 246.20 ? 718 TYR C CE1 1 
ATOM   11412 C CE2 . TYR C 3 674 ? 218.401 185.544 109.563 1.00 246.20 ? 718 TYR C CE2 1 
ATOM   11413 C CZ  . TYR C 3 674 ? 217.217 184.936 109.202 1.00 246.20 ? 718 TYR C CZ  1 
ATOM   11414 O OH  . TYR C 3 674 ? 217.044 184.486 107.913 1.00 246.20 ? 718 TYR C OH  1 
ATOM   11415 N N   . ILE C 3 675 ? 216.661 187.632 115.751 1.00 252.72 ? 719 ILE C N   1 
ATOM   11416 C CA  . ILE C 3 675 ? 216.757 187.912 117.180 1.00 252.72 ? 719 ILE C CA  1 
ATOM   11417 C C   . ILE C 3 675 ? 217.986 187.237 117.779 1.00 252.72 ? 719 ILE C C   1 
ATOM   11418 O O   . ILE C 3 675 ? 218.551 187.722 118.767 1.00 252.72 ? 719 ILE C O   1 
ATOM   11419 C CB  . ILE C 3 675 ? 215.460 187.484 117.895 1.00 252.72 ? 719 ILE C CB  1 
ATOM   11420 C CG1 . ILE C 3 675 ? 215.494 187.890 119.371 1.00 252.72 ? 719 ILE C CG1 1 
ATOM   11421 C CG2 . ILE C 3 675 ? 215.232 185.987 117.750 1.00 252.72 ? 719 ILE C CG2 1 
ATOM   11422 C CD1 . ILE C 3 675 ? 214.273 187.455 120.152 1.00 252.72 ? 719 ILE C CD1 1 
ATOM   11423 N N   . GLU C 3 676 ? 218.428 186.124 117.195 1.00 253.38 ? 720 GLU C N   1 
ATOM   11424 C CA  . GLU C 3 676 ? 219.606 185.413 117.667 1.00 253.38 ? 720 GLU C CA  1 
ATOM   11425 C C   . GLU C 3 676 ? 220.387 184.884 116.474 1.00 253.38 ? 720 GLU C C   1 
ATOM   11426 O O   . GLU C 3 676 ? 219.800 184.387 115.509 1.00 253.38 ? 720 GLU C O   1 
ATOM   11427 C CB  . GLU C 3 676 ? 219.226 184.260 118.608 1.00 253.38 ? 720 GLU C CB  1 
ATOM   11428 C CG  . GLU C 3 676 ? 218.140 183.341 118.069 1.00 253.38 ? 720 GLU C CG  1 
ATOM   11429 C CD  . GLU C 3 676 ? 218.702 182.139 117.336 1.00 253.38 ? 720 GLU C CD  1 
ATOM   11430 O OE1 . GLU C 3 676 ? 219.910 181.860 117.488 1.00 253.38 ? 720 GLU C OE1 1 
ATOM   11431 O OE2 . GLU C 3 676 ? 217.937 181.474 116.607 1.00 253.38 ? 720 GLU C OE2 1 
ATOM   11432 N N   . GLU C 3 677 ? 221.711 185.000 116.545 1.00 253.20 ? 721 GLU C N   1 
ATOM   11433 C CA  . GLU C 3 677 ? 222.597 184.518 115.490 1.00 253.20 ? 721 GLU C CA  1 
ATOM   11434 C C   . GLU C 3 677 ? 223.825 183.897 116.136 1.00 253.20 ? 721 GLU C C   1 
ATOM   11435 O O   . GLU C 3 677 ? 224.511 184.555 116.924 1.00 253.20 ? 721 GLU C O   1 
ATOM   11436 C CB  . GLU C 3 677 ? 223.001 185.648 114.538 1.00 253.20 ? 721 GLU C CB  1 
ATOM   11437 C CG  . GLU C 3 677 ? 221.871 186.158 113.656 1.00 253.20 ? 721 GLU C CG  1 
ATOM   11438 C CD  . GLU C 3 677 ? 222.359 187.081 112.557 1.00 253.20 ? 721 GLU C CD  1 
ATOM   11439 O OE1 . GLU C 3 677 ? 223.588 187.169 112.354 1.00 253.20 ? 721 GLU C OE1 1 
ATOM   11440 O OE2 . GLU C 3 677 ? 221.513 187.720 111.897 1.00 253.20 ? 721 GLU C OE2 1 
ATOM   11441 N N   . LEU C 3 678 ? 224.102 182.641 115.798 1.00 267.17 ? 722 LEU C N   1 
ATOM   11442 C CA  . LEU C 3 678 ? 225.234 181.914 116.357 1.00 267.17 ? 722 LEU C CA  1 
ATOM   11443 C C   . LEU C 3 678 ? 225.770 180.964 115.292 1.00 267.17 ? 722 LEU C C   1 
ATOM   11444 O O   . LEU C 3 678 ? 225.440 181.079 114.108 1.00 267.17 ? 722 LEU C O   1 
ATOM   11445 C CB  . LEU C 3 678 ? 224.827 181.171 117.637 1.00 267.17 ? 722 LEU C CB  1 
ATOM   11446 C CG  . LEU C 3 678 ? 224.746 181.989 118.928 1.00 267.17 ? 722 LEU C CG  1 
ATOM   11447 C CD1 . LEU C 3 678 ? 223.949 181.243 119.987 1.00 267.17 ? 722 LEU C CD1 1 
ATOM   11448 C CD2 . LEU C 3 678 ? 226.138 182.327 119.438 1.00 267.17 ? 722 LEU C CD2 1 
ATOM   11449 N N   . ALA C 3 679 ? 226.607 180.021 115.718 1.00 281.29 ? 723 ALA C N   1 
ATOM   11450 C CA  . ALA C 3 679 ? 227.166 179.051 114.795 1.00 281.29 ? 723 ALA C CA  1 
ATOM   11451 C C   . ALA C 3 679 ? 226.098 178.042 114.372 1.00 281.29 ? 723 ALA C C   1 
ATOM   11452 O O   . ALA C 3 679 ? 225.164 177.762 115.128 1.00 281.29 ? 723 ALA C O   1 
ATOM   11453 C CB  . ALA C 3 679 ? 228.345 178.323 115.435 1.00 281.29 ? 723 ALA C CB  1 
ATOM   11454 N N   . PRO C 3 680 ? 226.208 177.491 113.163 1.00 296.40 ? 724 PRO C N   1 
ATOM   11455 C CA  . PRO C 3 680 ? 225.239 176.480 112.727 1.00 296.40 ? 724 PRO C CA  1 
ATOM   11456 C C   . PRO C 3 680 ? 225.301 175.236 113.601 1.00 296.40 ? 724 PRO C C   1 
ATOM   11457 O O   . PRO C 3 680 ? 226.324 174.932 114.219 1.00 296.40 ? 724 PRO C O   1 
ATOM   11458 C CB  . PRO C 3 680 ? 225.665 176.173 111.285 1.00 296.40 ? 724 PRO C CB  1 
ATOM   11459 C CG  . PRO C 3 680 ? 226.460 177.364 110.858 1.00 296.40 ? 724 PRO C CG  1 
ATOM   11460 C CD  . PRO C 3 680 ? 227.155 177.847 112.093 1.00 296.40 ? 724 PRO C CD  1 
ATOM   11461 N N   . ILE C 3 681 ? 224.183 174.511 113.645 1.00 316.91 ? 725 ILE C N   1 
ATOM   11462 C CA  . ILE C 3 681 ? 224.090 173.326 114.490 1.00 316.91 ? 725 ILE C CA  1 
ATOM   11463 C C   . ILE C 3 681 ? 224.470 172.042 113.760 1.00 316.91 ? 725 ILE C C   1 
ATOM   11464 O O   . ILE C 3 681 ? 224.858 171.063 114.414 1.00 316.91 ? 725 ILE C O   1 
ATOM   11465 C CB  . ILE C 3 681 ? 222.673 173.182 115.074 1.00 316.91 ? 725 ILE C CB  1 
ATOM   11466 C CG1 . ILE C 3 681 ? 221.623 173.359 113.976 1.00 316.91 ? 725 ILE C CG1 1 
ATOM   11467 C CG2 . ILE C 3 681 ? 222.455 174.188 116.194 1.00 316.91 ? 725 ILE C CG2 1 
ATOM   11468 C CD1 . ILE C 3 681 ? 220.244 172.871 114.365 1.00 316.91 ? 725 ILE C CD1 1 
ATOM   11469 N N   . VAL C 3 682 ? 224.373 172.015 112.433 1.00 323.58 ? 726 VAL C N   1 
ATOM   11470 C CA  . VAL C 3 682 ? 224.706 170.833 111.650 1.00 323.58 ? 726 VAL C CA  1 
ATOM   11471 C C   . VAL C 3 682 ? 225.539 171.256 110.449 1.00 323.58 ? 726 VAL C C   1 
ATOM   11472 O O   . VAL C 3 682 ? 225.421 172.379 109.948 1.00 323.58 ? 726 VAL C O   1 
ATOM   11473 C CB  . VAL C 3 682 ? 223.440 170.060 111.206 1.00 323.58 ? 726 VAL C CB  1 
ATOM   11474 C CG1 . VAL C 3 682 ? 222.740 170.774 110.058 1.00 323.58 ? 726 VAL C CG1 1 
ATOM   11475 C CG2 . VAL C 3 682 ? 223.787 168.625 110.829 1.00 323.58 ? 726 VAL C CG2 1 
ATOM   11476 N N   . ALA C 3 683 ? 226.414 170.343 109.997 1.00 353.69 ? 727 ALA C N   1 
ATOM   11477 C CA  . ALA C 3 683 ? 227.266 170.561 108.840 1.00 353.69 ? 727 ALA C CA  1 
ATOM   11478 C C   . ALA C 3 683 ? 226.528 170.198 107.555 1.00 353.69 ? 727 ALA C C   1 
ATOM   11479 O O   . ALA C 3 683 ? 225.664 169.315 107.557 1.00 353.69 ? 727 ALA C O   1 
ATOM   11480 C CB  . ALA C 3 683 ? 228.540 169.727 108.954 1.00 353.69 ? 727 ALA C CB  1 
ATOM   11481 N N   . PRO C 3 684 ? 226.843 170.867 106.445 1.00 381.01 ? 728 PRO C N   1 
ATOM   11482 C CA  . PRO C 3 684 ? 226.159 170.558 105.181 1.00 381.01 ? 728 PRO C CA  1 
ATOM   11483 C C   . PRO C 3 684 ? 226.513 169.160 104.693 1.00 381.01 ? 728 PRO C C   1 
ATOM   11484 O O   . PRO C 3 684 ? 227.686 168.786 104.629 1.00 381.01 ? 728 PRO C O   1 
ATOM   11485 C CB  . PRO C 3 684 ? 226.673 171.639 104.223 1.00 381.01 ? 728 PRO C CB  1 
ATOM   11486 C CG  . PRO C 3 684 ? 227.967 172.091 104.817 1.00 381.01 ? 728 PRO C CG  1 
ATOM   11487 C CD  . PRO C 3 684 ? 227.797 171.980 106.302 1.00 381.01 ? 728 PRO C CD  1 
ATOM   11488 N N   . ASN C 3 685 ? 225.484 168.390 104.348 1.00 415.38 ? 729 ASN C N   1 
ATOM   11489 C CA  . ASN C 3 685 ? 225.690 167.032 103.865 1.00 415.38 ? 729 ASN C CA  1 
ATOM   11490 C C   . ASN C 3 685 ? 226.211 167.055 102.433 1.00 415.38 ? 729 ASN C C   1 
ATOM   11491 O O   . ASN C 3 685 ? 225.594 167.652 101.545 1.00 415.38 ? 729 ASN C O   1 
ATOM   11492 C CB  . ASN C 3 685 ? 224.388 166.237 103.944 1.00 415.38 ? 729 ASN C CB  1 
ATOM   11493 C CG  . ASN C 3 685 ? 224.562 164.789 103.529 1.00 415.38 ? 729 ASN C CG  1 
ATOM   11494 O OD1 . ASN C 3 685 ? 224.469 164.454 102.348 1.00 415.38 ? 729 ASN C OD1 1 
ATOM   11495 N ND2 . ASN C 3 685 ? 224.814 163.921 104.501 1.00 415.38 ? 729 ASN C ND2 1 
ATOM   11496 N N   . PHE C 3 686 ? 227.348 166.402 102.211 1.00 412.67 ? 730 PHE C N   1 
ATOM   11497 C CA  . PHE C 3 686 ? 227.977 166.340 100.903 1.00 412.67 ? 730 PHE C CA  1 
ATOM   11498 C C   . PHE C 3 686 ? 228.131 164.888 100.468 1.00 412.67 ? 730 PHE C C   1 
ATOM   11499 O O   . PHE C 3 686 ? 228.210 163.974 101.294 1.00 412.67 ? 730 PHE C O   1 
ATOM   11500 C CB  . PHE C 3 686 ? 229.345 167.039 100.909 1.00 412.67 ? 730 PHE C CB  1 
ATOM   11501 C CG  . PHE C 3 686 ? 230.293 166.513 101.951 1.00 412.67 ? 730 PHE C CG  1 
ATOM   11502 C CD1 . PHE C 3 686 ? 231.227 165.543 101.628 1.00 412.67 ? 730 PHE C CD1 1 
ATOM   11503 C CD2 . PHE C 3 686 ? 230.252 166.989 103.251 1.00 412.67 ? 730 PHE C CD2 1 
ATOM   11504 C CE1 . PHE C 3 686 ? 232.101 165.058 102.582 1.00 412.67 ? 730 PHE C CE1 1 
ATOM   11505 C CE2 . PHE C 3 686 ? 231.122 166.506 104.210 1.00 412.67 ? 730 PHE C CE2 1 
ATOM   11506 C CZ  . PHE C 3 686 ? 232.048 165.539 103.874 1.00 412.67 ? 730 PHE C CZ  1 
ATOM   11507 N N   . THR C 3 687 ? 228.171 164.687 99.153  1.00 402.36 ? 731 THR C N   1 
ATOM   11508 C CA  . THR C 3 687 ? 228.283 163.354 98.581  1.00 402.36 ? 731 THR C CA  1 
ATOM   11509 C C   . THR C 3 687 ? 229.169 163.422 97.346  1.00 402.36 ? 731 THR C C   1 
ATOM   11510 O O   . THR C 3 687 ? 229.197 164.442 96.652  1.00 402.36 ? 731 THR C O   1 
ATOM   11511 C CB  . THR C 3 687 ? 226.906 162.782 98.215  1.00 402.36 ? 731 THR C CB  1 
ATOM   11512 O OG1 . THR C 3 687 ? 225.969 163.083 99.256  1.00 402.36 ? 731 THR C OG1 1 
ATOM   11513 C CG2 . THR C 3 687 ? 226.981 161.272 98.037  1.00 402.36 ? 731 THR C CG2 1 
ATOM   11514 N N   . VAL C 3 688 ? 229.894 162.338 97.084  1.00 379.38 ? 732 VAL C N   1 
ATOM   11515 C CA  . VAL C 3 688 ? 230.763 162.260 95.916  1.00 379.38 ? 732 VAL C CA  1 
ATOM   11516 C C   . VAL C 3 688 ? 229.957 161.776 94.718  1.00 379.38 ? 732 VAL C C   1 
ATOM   11517 O O   . VAL C 3 688 ? 229.141 160.851 94.825  1.00 379.38 ? 732 VAL C O   1 
ATOM   11518 C CB  . VAL C 3 688 ? 231.968 161.343 96.201  1.00 379.38 ? 732 VAL C CB  1 
ATOM   11519 C CG1 . VAL C 3 688 ? 231.505 159.975 96.684  1.00 379.38 ? 732 VAL C CG1 1 
ATOM   11520 C CG2 . VAL C 3 688 ? 232.849 161.212 94.967  1.00 379.38 ? 732 VAL C CG2 1 
ATOM   11521 N N   . GLU C 3 689 ? 230.171 162.416 93.568  1.00 374.96 ? 733 GLU C N   1 
ATOM   11522 C CA  . GLU C 3 689 ? 229.476 162.063 92.334  1.00 374.96 ? 733 GLU C CA  1 
ATOM   11523 C C   . GLU C 3 689 ? 230.391 161.324 91.364  1.00 374.96 ? 733 GLU C C   1 
ATOM   11524 O O   . GLU C 3 689 ? 230.073 160.217 90.921  1.00 374.96 ? 733 GLU C O   1 
ATOM   11525 C CB  . GLU C 3 689 ? 228.903 163.322 91.666  1.00 374.96 ? 733 GLU C CB  1 
ATOM   11526 C CG  . GLU C 3 689 ? 227.623 163.854 92.294  1.00 374.96 ? 733 GLU C CG  1 
ATOM   11527 C CD  . GLU C 3 689 ? 227.801 164.239 93.746  1.00 374.96 ? 733 GLU C CD  1 
ATOM   11528 O OE1 . GLU C 3 689 ? 228.547 165.201 94.014  1.00 374.96 ? 733 GLU C OE1 1 
ATOM   11529 O OE2 . GLU C 3 689 ? 227.193 163.582 94.618  1.00 374.96 ? 733 GLU C OE2 1 
ATOM   11530 N N   . ASP C 3 690 ? 231.530 161.923 91.026  1.00 325.18 ? 734 ASP C N   1 
ATOM   11531 C CA  . ASP C 3 690 ? 232.491 161.327 90.112  1.00 325.18 ? 734 ASP C CA  1 
ATOM   11532 C C   . ASP C 3 690 ? 233.890 161.442 90.697  1.00 325.18 ? 734 ASP C C   1 
ATOM   11533 O O   . ASP C 3 690 ? 234.205 162.392 91.418  1.00 325.18 ? 734 ASP C O   1 
ATOM   11534 C CB  . ASP C 3 690 ? 232.447 161.995 88.730  1.00 325.18 ? 734 ASP C CB  1 
ATOM   11535 C CG  . ASP C 3 690 ? 231.035 162.150 88.202  1.00 325.18 ? 734 ASP C CG  1 
ATOM   11536 O OD1 . ASP C 3 690 ? 230.532 163.293 88.169  1.00 325.18 ? 734 ASP C OD1 1 
ATOM   11537 O OD2 . ASP C 3 690 ? 230.426 161.128 87.821  1.00 325.18 ? 734 ASP C OD2 1 
ATOM   11538 N N   . THR C 3 691 ? 234.727 160.457 90.379  1.00 277.05 ? 735 THR C N   1 
ATOM   11539 C CA  . THR C 3 691 ? 236.108 160.428 90.838  1.00 277.05 ? 735 THR C CA  1 
ATOM   11540 C C   . THR C 3 691 ? 236.971 159.814 89.749  1.00 277.05 ? 735 THR C C   1 
ATOM   11541 O O   . THR C 3 691 ? 236.645 158.744 89.226  1.00 277.05 ? 735 THR C O   1 
ATOM   11542 C CB  . THR C 3 691 ? 236.248 159.628 92.139  1.00 277.05 ? 735 THR C CB  1 
ATOM   11543 O OG1 . THR C 3 691 ? 235.430 160.218 93.157  1.00 277.05 ? 735 THR C OG1 1 
ATOM   11544 C CG2 . THR C 3 691 ? 237.696 159.614 92.605  1.00 277.05 ? 735 THR C CG2 1 
ATOM   11545 N N   . SER C 3 692 ? 238.061 160.490 89.409  1.00 269.94 ? 736 SER C N   1 
ATOM   11546 C CA  . SER C 3 692 ? 239.004 160.022 88.406  1.00 269.94 ? 736 SER C CA  1 
ATOM   11547 C C   . SER C 3 692 ? 240.297 159.582 89.083  1.00 269.94 ? 736 SER C C   1 
ATOM   11548 O O   . SER C 3 692 ? 240.429 159.613 90.310  1.00 269.94 ? 736 SER C O   1 
ATOM   11549 C CB  . SER C 3 692 ? 239.269 161.113 87.366  1.00 269.94 ? 736 SER C CB  1 
ATOM   11550 O OG  . SER C 3 692 ? 240.330 161.958 87.776  1.00 269.94 ? 736 SER C OG  1 
ATOM   11551 N N   . ALA C 3 693 ? 241.263 159.167 88.262  1.00 280.49 ? 737 ALA C N   1 
ATOM   11552 C CA  . ALA C 3 693 ? 242.564 158.775 88.789  1.00 280.49 ? 737 ALA C CA  1 
ATOM   11553 C C   . ALA C 3 693 ? 243.361 159.967 89.297  1.00 280.49 ? 737 ALA C C   1 
ATOM   11554 O O   . ALA C 3 693 ? 244.324 159.779 90.048  1.00 280.49 ? 737 ALA C O   1 
ATOM   11555 C CB  . ALA C 3 693 ? 243.364 158.030 87.720  1.00 280.49 ? 737 ALA C CB  1 
ATOM   11556 N N   . ASP C 3 694 ? 242.982 161.188 88.905  1.00 262.90 ? 738 ASP C N   1 
ATOM   11557 C CA  . ASP C 3 694 ? 243.686 162.381 89.354  1.00 262.90 ? 738 ASP C CA  1 
ATOM   11558 C C   . ASP C 3 694 ? 242.746 163.533 89.695  1.00 262.90 ? 738 ASP C C   1 
ATOM   11559 O O   . ASP C 3 694 ? 243.207 164.678 89.782  1.00 262.90 ? 738 ASP C O   1 
ATOM   11560 C CB  . ASP C 3 694 ? 244.701 162.833 88.295  1.00 262.90 ? 738 ASP C CB  1 
ATOM   11561 C CG  . ASP C 3 694 ? 244.119 162.844 86.896  1.00 262.90 ? 738 ASP C CG  1 
ATOM   11562 O OD1 . ASP C 3 694 ? 243.145 162.102 86.649  1.00 262.90 ? 738 ASP C OD1 1 
ATOM   11563 O OD2 . ASP C 3 694 ? 244.638 163.590 86.040  1.00 262.90 ? 738 ASP C OD2 1 
ATOM   11564 N N   . SER C 3 695 ? 241.453 163.276 89.889  1.00 268.94 ? 739 SER C N   1 
ATOM   11565 C CA  . SER C 3 695 ? 240.513 164.327 90.249  1.00 268.94 ? 739 SER C CA  1 
ATOM   11566 C C   . SER C 3 695 ? 239.312 163.717 90.957  1.00 268.94 ? 739 SER C C   1 
ATOM   11567 O O   . SER C 3 695 ? 238.970 162.551 90.739  1.00 268.94 ? 739 SER C O   1 
ATOM   11568 C CB  . SER C 3 695 ? 240.050 165.119 89.020  1.00 268.94 ? 739 SER C CB  1 
ATOM   11569 O OG  . SER C 3 695 ? 239.033 166.044 89.367  1.00 268.94 ? 739 SER C OG  1 
ATOM   11570 N N   . ILE C 3 696 ? 238.677 164.521 91.811  1.00 279.88 ? 740 ILE C N   1 
ATOM   11571 C CA  . ILE C 3 696 ? 237.467 164.133 92.523  1.00 279.88 ? 740 ILE C CA  1 
ATOM   11572 C C   . ILE C 3 696 ? 236.418 165.222 92.337  1.00 279.88 ? 740 ILE C C   1 
ATOM   11573 O O   . ILE C 3 696 ? 236.698 166.311 91.833  1.00 279.88 ? 740 ILE C O   1 
ATOM   11574 C CB  . ILE C 3 696 ? 237.717 163.877 94.025  1.00 279.88 ? 740 ILE C CB  1 
ATOM   11575 C CG1 . ILE C 3 696 ? 238.133 165.171 94.729  1.00 279.88 ? 740 ILE C CG1 1 
ATOM   11576 C CG2 . ILE C 3 696 ? 238.748 162.778 94.224  1.00 279.88 ? 740 ILE C CG2 1 
ATOM   11577 C CD1 . ILE C 3 696 ? 238.268 165.032 96.230  1.00 279.88 ? 740 ILE C CD1 1 
ATOM   11578 N N   . LEU C 3 697 ? 235.194 164.910 92.758  1.00 321.71 ? 741 LEU C N   1 
ATOM   11579 C CA  . LEU C 3 697 ? 234.071 165.829 92.642  1.00 321.71 ? 741 LEU C CA  1 
ATOM   11580 C C   . LEU C 3 697 ? 233.179 165.665 93.862  1.00 321.71 ? 741 LEU C C   1 
ATOM   11581 O O   . LEU C 3 697 ? 232.896 164.538 94.278  1.00 321.71 ? 741 LEU C O   1 
ATOM   11582 C CB  . LEU C 3 697 ? 233.277 165.567 91.356  1.00 321.71 ? 741 LEU C CB  1 
ATOM   11583 C CG  . LEU C 3 697 ? 231.990 166.358 91.107  1.00 321.71 ? 741 LEU C CG  1 
ATOM   11584 C CD1 . LEU C 3 697 ? 232.197 167.843 91.371  1.00 321.71 ? 741 LEU C CD1 1 
ATOM   11585 C CD2 . LEU C 3 697 ? 231.486 166.123 89.690  1.00 321.71 ? 741 LEU C CD2 1 
ATOM   11586 N N   . VAL C 3 698 ? 232.741 166.787 94.433  1.00 360.88 ? 742 VAL C N   1 
ATOM   11587 C CA  . VAL C 3 698 ? 231.896 166.785 95.620  1.00 360.88 ? 742 VAL C CA  1 
ATOM   11588 C C   . VAL C 3 698 ? 230.786 167.811 95.428  1.00 360.88 ? 742 VAL C C   1 
ATOM   11589 O O   . VAL C 3 698 ? 230.916 168.758 94.646  1.00 360.88 ? 742 VAL C O   1 
ATOM   11590 C CB  . VAL C 3 698 ? 232.712 167.076 96.904  1.00 360.88 ? 742 VAL C CB  1 
ATOM   11591 C CG1 . VAL C 3 698 ? 233.042 168.559 97.015  1.00 360.88 ? 742 VAL C CG1 1 
ATOM   11592 C CG2 . VAL C 3 698 ? 231.978 166.576 98.144  1.00 360.88 ? 742 VAL C CG2 1 
ATOM   11593 N N   . LYS C 3 699 ? 229.679 167.604 96.139  1.00 405.24 ? 743 LYS C N   1 
ATOM   11594 C CA  . LYS C 3 699 ? 228.519 168.482 96.047  1.00 405.24 ? 743 LYS C CA  1 
ATOM   11595 C C   . LYS C 3 699 ? 227.816 168.492 97.395  1.00 405.24 ? 743 LYS C C   1 
ATOM   11596 O O   . LYS C 3 699 ? 227.374 167.443 97.872  1.00 405.24 ? 743 LYS C O   1 
ATOM   11597 C CB  . LYS C 3 699 ? 227.565 168.011 94.940  1.00 405.24 ? 743 LYS C CB  1 
ATOM   11598 C CG  . LYS C 3 699 ? 226.243 168.768 94.801  1.00 405.24 ? 743 LYS C CG  1 
ATOM   11599 C CD  . LYS C 3 699 ? 226.376 170.263 95.042  1.00 405.24 ? 743 LYS C CD  1 
ATOM   11600 C CE  . LYS C 3 699 ? 225.032 170.961 94.898  1.00 405.24 ? 743 LYS C CE  1 
ATOM   11601 N NZ  . LYS C 3 699 ? 223.977 170.333 95.742  1.00 405.24 ? 743 LYS C NZ  1 
ATOM   11602 N N   . TRP C 3 700 ? 227.710 169.672 97.998  1.00 396.14 ? 744 TRP C N   1 
ATOM   11603 C CA  . TRP C 3 700 ? 227.021 169.844 99.267  1.00 396.14 ? 744 TRP C CA  1 
ATOM   11604 C C   . TRP C 3 700 ? 225.678 170.525 99.040  1.00 396.14 ? 744 TRP C C   1 
ATOM   11605 O O   . TRP C 3 700 ? 225.526 171.351 98.134  1.00 396.14 ? 744 TRP C O   1 
ATOM   11606 C CB  . TRP C 3 700 ? 227.864 170.666 100.250 1.00 396.14 ? 744 TRP C CB  1 
ATOM   11607 C CG  . TRP C 3 700 ? 228.367 171.961 99.685  1.00 396.14 ? 744 TRP C CG  1 
ATOM   11608 C CD1 . TRP C 3 700 ? 227.695 173.146 99.635  1.00 396.14 ? 744 TRP C CD1 1 
ATOM   11609 C CD2 . TRP C 3 700 ? 229.655 172.205 99.102  1.00 396.14 ? 744 TRP C CD2 1 
ATOM   11610 N NE1 . TRP C 3 700 ? 228.479 174.112 99.051  1.00 396.14 ? 744 TRP C NE1 1 
ATOM   11611 C CE2 . TRP C 3 700 ? 229.687 173.560 98.716  1.00 396.14 ? 744 TRP C CE2 1 
ATOM   11612 C CE3 . TRP C 3 700 ? 230.781 171.410 98.866  1.00 396.14 ? 744 TRP C CE3 1 
ATOM   11613 C CZ2 . TRP C 3 700 ? 230.801 174.138 98.107  1.00 396.14 ? 744 TRP C CZ2 1 
ATOM   11614 C CZ3 . TRP C 3 700 ? 231.886 171.986 98.261  1.00 396.14 ? 744 TRP C CZ3 1 
ATOM   11615 C CH2 . TRP C 3 700 ? 231.887 173.336 97.889  1.00 396.14 ? 744 TRP C CH2 1 
ATOM   11616 N N   . GLU C 3 701 ? 224.703 170.169 99.869  1.00 374.66 ? 745 GLU C N   1 
ATOM   11617 C CA  . GLU C 3 701 ? 223.365 170.734 99.774  1.00 374.66 ? 745 GLU C CA  1 
ATOM   11618 C C   . GLU C 3 701 ? 223.289 172.048 100.540 1.00 374.66 ? 745 GLU C C   1 
ATOM   11619 O O   . GLU C 3 701 ? 223.945 172.230 101.569 1.00 374.66 ? 745 GLU C O   1 
ATOM   11620 C CB  . GLU C 3 701 ? 222.323 169.751 100.311 1.00 374.66 ? 745 GLU C CB  1 
ATOM   11621 C CG  . GLU C 3 701 ? 220.902 170.027 99.844  1.00 374.66 ? 745 GLU C CG  1 
ATOM   11622 C CD  . GLU C 3 701 ? 220.055 170.696 100.909 1.00 374.66 ? 745 GLU C CD  1 
ATOM   11623 O OE1 . GLU C 3 701 ? 220.406 170.591 102.103 1.00 374.66 ? 745 GLU C OE1 1 
ATOM   11624 O OE2 . GLU C 3 701 ? 219.036 171.324 100.552 1.00 374.66 ? 745 GLU C OE2 1 
ATOM   11625 N N   . ASP C 3 702 ? 222.480 172.969 100.020 1.00 353.21 ? 746 ASP C N   1 
ATOM   11626 C CA  . ASP C 3 702 ? 222.336 174.280 100.639 1.00 353.21 ? 746 ASP C CA  1 
ATOM   11627 C C   . ASP C 3 702 ? 221.699 174.151 102.017 1.00 353.21 ? 746 ASP C C   1 
ATOM   11628 O O   . ASP C 3 702 ? 220.679 173.476 102.184 1.00 353.21 ? 746 ASP C O   1 
ATOM   11629 C CB  . ASP C 3 702 ? 221.501 175.198 99.746  1.00 353.21 ? 746 ASP C CB  1 
ATOM   11630 C CG  . ASP C 3 702 ? 220.174 174.578 99.348  1.00 353.21 ? 746 ASP C CG  1 
ATOM   11631 O OD1 . ASP C 3 702 ? 219.198 174.711 100.116 1.00 353.21 ? 746 ASP C OD1 1 
ATOM   11632 O OD2 . ASP C 3 702 ? 220.106 173.960 98.265  1.00 353.21 ? 746 ASP C OD2 1 
ATOM   11633 N N   . ILE C 3 703 ? 222.306 174.796 103.004 1.00 310.90 ? 747 ILE C N   1 
ATOM   11634 C CA  . ILE C 3 703 ? 221.809 174.723 104.379 1.00 310.90 ? 747 ILE C CA  1 
ATOM   11635 C C   . ILE C 3 703 ? 220.638 175.690 104.531 1.00 310.90 ? 747 ILE C C   1 
ATOM   11636 O O   . ILE C 3 703 ? 220.781 176.878 104.201 1.00 310.90 ? 747 ILE C O   1 
ATOM   11637 C CB  . ILE C 3 703 ? 222.920 175.048 105.370 1.00 310.90 ? 747 ILE C CB  1 
ATOM   11638 C CG1 . ILE C 3 703 ? 224.241 174.424 104.916 1.00 310.90 ? 747 ILE C CG1 1 
ATOM   11639 C CG2 . ILE C 3 703 ? 222.554 174.555 106.761 1.00 310.90 ? 747 ILE C CG2 1 
ATOM   11640 C CD1 . ILE C 3 703 ? 225.418 174.783 105.797 1.00 310.90 ? 747 ILE C CD1 1 
ATOM   11641 N N   . PRO C 3 704 ? 219.483 175.232 105.007 1.00 289.57 ? 748 PRO C N   1 
ATOM   11642 C CA  . PRO C 3 704 ? 218.359 176.148 105.223 1.00 289.57 ? 748 PRO C CA  1 
ATOM   11643 C C   . PRO C 3 704 ? 218.669 177.162 106.313 1.00 289.57 ? 748 PRO C C   1 
ATOM   11644 O O   . PRO C 3 704 ? 219.528 176.958 107.173 1.00 289.57 ? 748 PRO C O   1 
ATOM   11645 C CB  . PRO C 3 704 ? 217.212 175.219 105.641 1.00 289.57 ? 748 PRO C CB  1 
ATOM   11646 C CG  . PRO C 3 704 ? 217.627 173.855 105.180 1.00 289.57 ? 748 PRO C CG  1 
ATOM   11647 C CD  . PRO C 3 704 ? 219.119 173.833 105.281 1.00 289.57 ? 748 PRO C CD  1 
ATOM   11648 N N   . VAL C 3 705 ? 217.940 178.280 106.264 1.00 270.44 ? 749 VAL C N   1 
ATOM   11649 C CA  . VAL C 3 705 ? 218.141 179.356 107.228 1.00 270.44 ? 749 VAL C CA  1 
ATOM   11650 C C   . VAL C 3 705 ? 217.620 179.015 108.614 1.00 270.44 ? 749 VAL C C   1 
ATOM   11651 O O   . VAL C 3 705 ? 217.931 179.729 109.574 1.00 270.44 ? 749 VAL C O   1 
ATOM   11652 C CB  . VAL C 3 705 ? 217.473 180.655 106.734 1.00 270.44 ? 749 VAL C CB  1 
ATOM   11653 C CG1 . VAL C 3 705 ? 218.274 181.261 105.591 1.00 270.44 ? 749 VAL C CG1 1 
ATOM   11654 C CG2 . VAL C 3 705 ? 216.039 180.384 106.304 1.00 270.44 ? 749 VAL C CG2 1 
ATOM   11655 N N   . GLU C 3 706 ? 216.835 177.943 108.747 1.00 273.97 ? 750 GLU C N   1 
ATOM   11656 C CA  . GLU C 3 706 ? 216.313 177.571 110.058 1.00 273.97 ? 750 GLU C CA  1 
ATOM   11657 C C   . GLU C 3 706 ? 217.411 177.013 110.954 1.00 273.97 ? 750 GLU C C   1 
ATOM   11658 O O   . GLU C 3 706 ? 217.400 177.237 112.170 1.00 273.97 ? 750 GLU C O   1 
ATOM   11659 C CB  . GLU C 3 706 ? 215.179 176.557 109.904 1.00 273.97 ? 750 GLU C CB  1 
ATOM   11660 C CG  . GLU C 3 706 ? 213.868 177.155 109.417 1.00 273.97 ? 750 GLU C CG  1 
ATOM   11661 C CD  . GLU C 3 706 ? 213.849 177.382 107.918 1.00 273.97 ? 750 GLU C CD  1 
ATOM   11662 O OE1 . GLU C 3 706 ? 214.732 176.839 107.221 1.00 273.97 ? 750 GLU C OE1 1 
ATOM   11663 O OE2 . GLU C 3 706 ? 212.951 178.105 107.436 1.00 273.97 ? 750 GLU C OE2 1 
ATOM   11664 N N   . GLU C 3 707 ? 218.367 176.287 110.376 1.00 280.76 ? 751 GLU C N   1 
ATOM   11665 C CA  . GLU C 3 707 ? 219.467 175.710 111.135 1.00 280.76 ? 751 GLU C CA  1 
ATOM   11666 C C   . GLU C 3 707 ? 220.782 176.457 110.949 1.00 280.76 ? 751 GLU C C   1 
ATOM   11667 O O   . GLU C 3 707 ? 221.747 176.162 111.661 1.00 280.76 ? 751 GLU C O   1 
ATOM   11668 C CB  . GLU C 3 707 ? 219.661 174.237 110.754 1.00 280.76 ? 751 GLU C CB  1 
ATOM   11669 C CG  . GLU C 3 707 ? 219.879 173.999 109.270 1.00 280.76 ? 751 GLU C CG  1 
ATOM   11670 C CD  . GLU C 3 707 ? 219.924 172.525 108.919 1.00 280.76 ? 751 GLU C CD  1 
ATOM   11671 O OE1 . GLU C 3 707 ? 219.477 171.702 109.745 1.00 280.76 ? 751 GLU C OE1 1 
ATOM   11672 O OE2 . GLU C 3 707 ? 220.408 172.188 107.818 1.00 280.76 ? 751 GLU C OE2 1 
ATOM   11673 N N   . LEU C 3 708 ? 220.845 177.408 110.014 1.00 272.89 ? 752 LEU C N   1 
ATOM   11674 C CA  . LEU C 3 708 ? 222.069 178.182 109.834 1.00 272.89 ? 752 LEU C CA  1 
ATOM   11675 C C   . LEU C 3 708 ? 222.295 179.134 111.002 1.00 272.89 ? 752 LEU C C   1 
ATOM   11676 O O   . LEU C 3 708 ? 223.439 179.343 111.425 1.00 272.89 ? 752 LEU C O   1 
ATOM   11677 C CB  . LEU C 3 708 ? 222.014 178.954 108.517 1.00 272.89 ? 752 LEU C CB  1 
ATOM   11678 C CG  . LEU C 3 708 ? 222.616 178.262 107.293 1.00 272.89 ? 752 LEU C CG  1 
ATOM   11679 C CD1 . LEU C 3 708 ? 222.418 179.110 106.046 1.00 272.89 ? 752 LEU C CD1 1 
ATOM   11680 C CD2 . LEU C 3 708 ? 224.091 177.964 107.515 1.00 272.89 ? 752 LEU C CD2 1 
ATOM   11681 N N   . ARG C 3 709 ? 221.217 179.716 111.533 1.00 271.11 ? 753 ARG C N   1 
ATOM   11682 C CA  . ARG C 3 709 ? 221.285 180.642 112.666 1.00 271.11 ? 753 ARG C CA  1 
ATOM   11683 C C   . ARG C 3 709 ? 222.206 181.823 112.366 1.00 271.11 ? 753 ARG C C   1 
ATOM   11684 O O   . ARG C 3 709 ? 223.006 182.240 113.205 1.00 271.11 ? 753 ARG C O   1 
ATOM   11685 C CB  . ARG C 3 709 ? 221.720 179.922 113.944 1.00 271.11 ? 753 ARG C CB  1 
ATOM   11686 C CG  . ARG C 3 709 ? 220.912 178.673 114.257 1.00 271.11 ? 753 ARG C CG  1 
ATOM   11687 C CD  . ARG C 3 709 ? 221.395 178.008 115.535 1.00 271.11 ? 753 ARG C CD  1 
ATOM   11688 N NE  . ARG C 3 709 ? 221.181 178.855 116.705 1.00 271.11 ? 753 ARG C NE  1 
ATOM   11689 C CZ  . ARG C 3 709 ? 221.509 178.511 117.946 1.00 271.11 ? 753 ARG C CZ  1 
ATOM   11690 N NH1 . ARG C 3 709 ? 222.068 177.332 118.184 1.00 271.11 ? 753 ARG C NH1 1 
ATOM   11691 N NH2 . ARG C 3 709 ? 221.278 179.345 118.951 1.00 271.11 ? 753 ARG C NH2 1 
ATOM   11692 N N   . GLY C 3 710 ? 222.093 182.362 111.166 1.00 257.80 ? 754 GLY C N   1 
ATOM   11693 C CA  . GLY C 3 710 ? 222.909 183.490 110.763 1.00 257.80 ? 754 GLY C CA  1 
ATOM   11694 C C   . GLY C 3 710 ? 223.188 183.442 109.275 1.00 257.80 ? 754 GLY C C   1 
ATOM   11695 O O   . GLY C 3 710 ? 222.706 182.573 108.553 1.00 257.80 ? 754 GLY C O   1 
ATOM   11696 N N   . PHE C 3 711 ? 223.987 184.408 108.832 1.00 263.14 ? 755 PHE C N   1 
ATOM   11697 C CA  . PHE C 3 711 ? 224.366 184.524 107.430 1.00 263.14 ? 755 PHE C CA  1 
ATOM   11698 C C   . PHE C 3 711 ? 225.606 183.676 107.171 1.00 263.14 ? 755 PHE C C   1 
ATOM   11699 O O   . PHE C 3 711 ? 226.670 183.932 107.744 1.00 263.14 ? 755 PHE C O   1 
ATOM   11700 C CB  . PHE C 3 711 ? 224.623 185.984 107.059 1.00 263.14 ? 755 PHE C CB  1 
ATOM   11701 C CG  . PHE C 3 711 ? 223.466 186.896 107.350 1.00 263.14 ? 755 PHE C CG  1 
ATOM   11702 C CD1 . PHE C 3 711 ? 222.437 187.045 106.434 1.00 263.14 ? 755 PHE C CD1 1 
ATOM   11703 C CD2 . PHE C 3 711 ? 223.406 187.605 108.538 1.00 263.14 ? 755 PHE C CD2 1 
ATOM   11704 C CE1 . PHE C 3 711 ? 221.370 187.884 106.699 1.00 263.14 ? 755 PHE C CE1 1 
ATOM   11705 C CE2 . PHE C 3 711 ? 222.342 188.445 108.809 1.00 263.14 ? 755 PHE C CE2 1 
ATOM   11706 C CZ  . PHE C 3 711 ? 221.323 188.585 107.887 1.00 263.14 ? 755 PHE C CZ  1 
ATOM   11707 N N   . LEU C 3 712 ? 225.466 182.671 106.310 1.00 283.09 ? 756 LEU C N   1 
ATOM   11708 C CA  . LEU C 3 712 ? 226.587 181.799 105.988 1.00 283.09 ? 756 LEU C CA  1 
ATOM   11709 C C   . LEU C 3 712 ? 227.587 182.533 105.103 1.00 283.09 ? 756 LEU C C   1 
ATOM   11710 O O   . LEU C 3 712 ? 227.229 183.057 104.044 1.00 283.09 ? 756 LEU C O   1 
ATOM   11711 C CB  . LEU C 3 712 ? 226.089 180.532 105.293 1.00 283.09 ? 756 LEU C CB  1 
ATOM   11712 C CG  . LEU C 3 712 ? 227.133 179.448 105.022 1.00 283.09 ? 756 LEU C CG  1 
ATOM   11713 C CD1 . LEU C 3 712 ? 227.820 179.030 106.312 1.00 283.09 ? 756 LEU C CD1 1 
ATOM   11714 C CD2 . LEU C 3 712 ? 226.491 178.250 104.341 1.00 283.09 ? 756 LEU C CD2 1 
ATOM   11715 N N   . ARG C 3 713 ? 228.845 182.568 105.541 1.00 293.76 ? 757 ARG C N   1 
ATOM   11716 C CA  . ARG C 3 713 ? 229.888 183.277 104.812 1.00 293.76 ? 757 ARG C CA  1 
ATOM   11717 C C   . ARG C 3 713 ? 230.619 182.402 103.804 1.00 293.76 ? 757 ARG C C   1 
ATOM   11718 O O   . ARG C 3 713 ? 231.222 182.935 102.866 1.00 293.76 ? 757 ARG C O   1 
ATOM   11719 C CB  . ARG C 3 713 ? 230.905 183.874 105.791 1.00 293.76 ? 757 ARG C CB  1 
ATOM   11720 C CG  . ARG C 3 713 ? 230.310 184.877 106.765 1.00 293.76 ? 757 ARG C CG  1 
ATOM   11721 C CD  . ARG C 3 713 ? 229.715 186.069 106.034 1.00 293.76 ? 757 ARG C CD  1 
ATOM   11722 N NE  . ARG C 3 713 ? 229.119 187.033 106.954 1.00 293.76 ? 757 ARG C NE  1 
ATOM   11723 C CZ  . ARG C 3 713 ? 228.548 188.173 106.576 1.00 293.76 ? 757 ARG C CZ  1 
ATOM   11724 N NH1 . ARG C 3 713 ? 228.496 188.496 105.291 1.00 293.76 ? 757 ARG C NH1 1 
ATOM   11725 N NH2 . ARG C 3 713 ? 228.031 188.990 107.482 1.00 293.76 ? 757 ARG C NH2 1 
ATOM   11726 N N   . GLY C 3 714 ? 230.582 181.084 103.969 1.00 320.37 ? 758 GLY C N   1 
ATOM   11727 C CA  . GLY C 3 714 ? 231.262 180.204 103.038 1.00 320.37 ? 758 GLY C CA  1 
ATOM   11728 C C   . GLY C 3 714 ? 231.386 178.805 103.608 1.00 320.37 ? 758 GLY C C   1 
ATOM   11729 O O   . GLY C 3 714 ? 230.692 178.444 104.560 1.00 320.37 ? 758 GLY C O   1 
ATOM   11730 N N   . TYR C 3 715 ? 232.286 178.029 103.008 1.00 351.63 ? 759 TYR C N   1 
ATOM   11731 C CA  . TYR C 3 715 ? 232.526 176.649 103.404 1.00 351.63 ? 759 TYR C CA  1 
ATOM   11732 C C   . TYR C 3 715 ? 234.022 176.404 103.522 1.00 351.63 ? 759 TYR C C   1 
ATOM   11733 O O   . TYR C 3 715 ? 234.810 176.916 102.721 1.00 351.63 ? 759 TYR C O   1 
ATOM   11734 C CB  . TYR C 3 715 ? 231.914 175.663 102.400 1.00 351.63 ? 759 TYR C CB  1 
ATOM   11735 C CG  . TYR C 3 715 ? 230.441 175.883 102.139 1.00 351.63 ? 759 TYR C CG  1 
ATOM   11736 C CD1 . TYR C 3 715 ? 229.478 175.261 102.922 1.00 351.63 ? 759 TYR C CD1 1 
ATOM   11737 C CD2 . TYR C 3 715 ? 230.014 176.708 101.107 1.00 351.63 ? 759 TYR C CD2 1 
ATOM   11738 C CE1 . TYR C 3 715 ? 228.130 175.458 102.687 1.00 351.63 ? 759 TYR C CE1 1 
ATOM   11739 C CE2 . TYR C 3 715 ? 228.669 176.911 100.864 1.00 351.63 ? 759 TYR C CE2 1 
ATOM   11740 C CZ  . TYR C 3 715 ? 227.732 176.284 101.657 1.00 351.63 ? 759 TYR C CZ  1 
ATOM   11741 O OH  . TYR C 3 715 ? 226.391 176.483 101.419 1.00 351.63 ? 759 TYR C OH  1 
ATOM   11742 N N   . LEU C 3 716 ? 234.408 175.620 104.526 1.00 352.07 ? 760 LEU C N   1 
ATOM   11743 C CA  . LEU C 3 716 ? 235.801 175.249 104.758 1.00 352.07 ? 760 LEU C CA  1 
ATOM   11744 C C   . LEU C 3 716 ? 235.951 173.761 104.467 1.00 352.07 ? 760 LEU C C   1 
ATOM   11745 O O   . LEU C 3 716 ? 235.536 172.920 105.273 1.00 352.07 ? 760 LEU C O   1 
ATOM   11746 C CB  . LEU C 3 716 ? 236.224 175.580 106.187 1.00 352.07 ? 760 LEU C CB  1 
ATOM   11747 C CG  . LEU C 3 716 ? 236.092 177.046 106.605 1.00 352.07 ? 760 LEU C CG  1 
ATOM   11748 C CD1 . LEU C 3 716 ? 236.497 177.233 108.059 1.00 352.07 ? 760 LEU C CD1 1 
ATOM   11749 C CD2 . LEU C 3 716 ? 236.919 177.941 105.695 1.00 352.07 ? 760 LEU C CD2 1 
ATOM   11750 N N   . PHE C 3 717 ? 236.542 173.440 103.320 1.00 375.73 ? 761 PHE C N   1 
ATOM   11751 C CA  . PHE C 3 717 ? 236.732 172.061 102.890 1.00 375.73 ? 761 PHE C CA  1 
ATOM   11752 C C   . PHE C 3 717 ? 238.153 171.616 103.211 1.00 375.73 ? 761 PHE C C   1 
ATOM   11753 O O   . PHE C 3 717 ? 239.120 172.273 102.811 1.00 375.73 ? 761 PHE C O   1 
ATOM   11754 C CB  . PHE C 3 717 ? 236.458 171.915 101.393 1.00 375.73 ? 761 PHE C CB  1 
ATOM   11755 C CG  . PHE C 3 717 ? 235.846 170.597 101.013 1.00 375.73 ? 761 PHE C CG  1 
ATOM   11756 C CD1 . PHE C 3 717 ? 236.631 169.571 100.514 1.00 375.73 ? 761 PHE C CD1 1 
ATOM   11757 C CD2 . PHE C 3 717 ? 234.484 170.385 101.152 1.00 375.73 ? 761 PHE C CD2 1 
ATOM   11758 C CE1 . PHE C 3 717 ? 236.069 168.358 100.163 1.00 375.73 ? 761 PHE C CE1 1 
ATOM   11759 C CE2 . PHE C 3 717 ? 233.917 169.174 100.803 1.00 375.73 ? 761 PHE C CE2 1 
ATOM   11760 C CZ  . PHE C 3 717 ? 234.711 168.159 100.308 1.00 375.73 ? 761 PHE C CZ  1 
ATOM   11761 N N   . TYR C 3 718 ? 238.273 170.504 103.930 1.00 367.78 ? 762 TYR C N   1 
ATOM   11762 C CA  . TYR C 3 718 ? 239.562 169.944 104.308 1.00 367.78 ? 762 TYR C CA  1 
ATOM   11763 C C   . TYR C 3 718 ? 239.745 168.584 103.649 1.00 367.78 ? 762 TYR C C   1 
ATOM   11764 O O   . TYR C 3 718 ? 238.789 167.812 103.520 1.00 367.78 ? 762 TYR C O   1 
ATOM   11765 C CB  . TYR C 3 718 ? 239.682 169.807 105.830 1.00 367.78 ? 762 TYR C CB  1 
ATOM   11766 C CG  . TYR C 3 718 ? 239.291 171.054 106.590 1.00 367.78 ? 762 TYR C CG  1 
ATOM   11767 C CD1 . TYR C 3 718 ? 240.201 172.084 106.786 1.00 367.78 ? 762 TYR C CD1 1 
ATOM   11768 C CD2 . TYR C 3 718 ? 238.014 171.199 107.115 1.00 367.78 ? 762 TYR C CD2 1 
ATOM   11769 C CE1 . TYR C 3 718 ? 239.849 173.225 107.481 1.00 367.78 ? 762 TYR C CE1 1 
ATOM   11770 C CE2 . TYR C 3 718 ? 237.653 172.336 107.812 1.00 367.78 ? 762 TYR C CE2 1 
ATOM   11771 C CZ  . TYR C 3 718 ? 238.574 173.346 107.992 1.00 367.78 ? 762 TYR C CZ  1 
ATOM   11772 O OH  . TYR C 3 718 ? 238.220 174.480 108.686 1.00 367.78 ? 762 TYR C OH  1 
ATOM   11773 N N   . PHE C 3 719 ? 240.976 168.297 103.235 1.00 349.72 ? 763 PHE C N   1 
ATOM   11774 C CA  . PHE C 3 719 ? 241.297 167.035 102.586 1.00 349.72 ? 763 PHE C CA  1 
ATOM   11775 C C   . PHE C 3 719 ? 242.762 166.710 102.833 1.00 349.72 ? 763 PHE C C   1 
ATOM   11776 O O   . PHE C 3 719 ? 243.612 167.604 102.828 1.00 349.72 ? 763 PHE C O   1 
ATOM   11777 C CB  . PHE C 3 719 ? 241.010 167.084 101.079 1.00 349.72 ? 763 PHE C CB  1 
ATOM   11778 C CG  . PHE C 3 719 ? 241.906 168.022 100.319 1.00 349.72 ? 763 PHE C CG  1 
ATOM   11779 C CD1 . PHE C 3 719 ? 241.713 169.393 100.381 1.00 349.72 ? 763 PHE C CD1 1 
ATOM   11780 C CD2 . PHE C 3 719 ? 242.942 167.532 99.540  1.00 349.72 ? 763 PHE C CD2 1 
ATOM   11781 C CE1 . PHE C 3 719 ? 242.535 170.257 99.683  1.00 349.72 ? 763 PHE C CE1 1 
ATOM   11782 C CE2 . PHE C 3 719 ? 243.768 168.391 98.839  1.00 349.72 ? 763 PHE C CE2 1 
ATOM   11783 C CZ  . PHE C 3 719 ? 243.564 169.755 98.910  1.00 349.72 ? 763 PHE C CZ  1 
ATOM   11784 N N   . GLY C 3 720 ? 243.046 165.431 103.051 1.00 332.56 ? 764 GLY C N   1 
ATOM   11785 C CA  . GLY C 3 720 ? 244.407 164.998 103.296 1.00 332.56 ? 764 GLY C CA  1 
ATOM   11786 C C   . GLY C 3 720 ? 244.479 163.494 103.411 1.00 332.56 ? 764 GLY C C   1 
ATOM   11787 O O   . GLY C 3 720 ? 243.466 162.816 103.608 1.00 332.56 ? 764 GLY C O   1 
ATOM   11788 N N   . LYS C 3 721 ? 245.701 162.982 103.286 1.00 328.29 ? 765 LYS C N   1 
ATOM   11789 C CA  . LYS C 3 721 ? 245.924 161.545 103.363 1.00 328.29 ? 765 LYS C CA  1 
ATOM   11790 C C   . LYS C 3 721 ? 245.579 161.020 104.752 1.00 328.29 ? 765 LYS C C   1 
ATOM   11791 O O   . LYS C 3 721 ? 245.956 161.608 105.769 1.00 328.29 ? 765 LYS C O   1 
ATOM   11792 C CB  . LYS C 3 721 ? 247.378 161.214 103.026 1.00 328.29 ? 765 LYS C CB  1 
ATOM   11793 C CG  . LYS C 3 721 ? 247.766 161.509 101.587 1.00 328.29 ? 765 LYS C CG  1 
ATOM   11794 C CD  . LYS C 3 721 ? 249.176 161.031 101.282 1.00 328.29 ? 765 LYS C CD  1 
ATOM   11795 C CE  . LYS C 3 721 ? 249.532 161.262 99.823  1.00 328.29 ? 765 LYS C CE  1 
ATOM   11796 N NZ  . LYS C 3 721 ? 250.899 160.769 99.500  1.00 328.29 ? 765 LYS C NZ  1 
ATOM   11797 N N   . GLY C 3 722 ? 244.858 159.904 104.788 1.00 334.72 ? 766 GLY C N   1 
ATOM   11798 C CA  . GLY C 3 722 ? 244.459 159.294 106.043 1.00 334.72 ? 766 GLY C CA  1 
ATOM   11799 C C   . GLY C 3 722 ? 243.725 157.979 105.866 1.00 334.72 ? 766 GLY C C   1 
ATOM   11800 O O   . GLY C 3 722 ? 242.768 157.890 105.096 1.00 334.72 ? 766 GLY C O   1 
ATOM   11801 N N   . ASP C 3 738 ? 249.845 167.365 106.924 1.00 364.60 ? 782 ASP C N   1 
ATOM   11802 C CA  . ASP C 3 738 ? 249.676 166.785 105.597 1.00 364.60 ? 782 ASP C CA  1 
ATOM   11803 C C   . ASP C 3 738 ? 248.302 167.116 105.026 1.00 364.60 ? 782 ASP C C   1 
ATOM   11804 O O   . ASP C 3 738 ? 247.931 166.632 103.956 1.00 364.60 ? 782 ASP C O   1 
ATOM   11805 C CB  . ASP C 3 738 ? 249.875 165.269 105.645 1.00 364.60 ? 782 ASP C CB  1 
ATOM   11806 C CG  . ASP C 3 738 ? 248.837 164.573 106.502 1.00 364.60 ? 782 ASP C CG  1 
ATOM   11807 O OD1 . ASP C 3 738 ? 248.516 165.095 107.590 1.00 364.60 ? 782 ASP C OD1 1 
ATOM   11808 O OD2 . ASP C 3 738 ? 248.342 163.503 106.089 1.00 364.60 ? 782 ASP C OD2 1 
ATOM   11809 N N   . ILE C 3 739 ? 247.550 167.943 105.745 1.00 356.44 ? 783 ILE C N   1 
ATOM   11810 C CA  . ILE C 3 739 ? 246.214 168.351 105.330 1.00 356.44 ? 783 ILE C CA  1 
ATOM   11811 C C   . ILE C 3 739 ? 246.282 169.758 104.758 1.00 356.44 ? 783 ILE C C   1 
ATOM   11812 O O   . ILE C 3 739 ? 247.132 170.571 105.141 1.00 356.44 ? 783 ILE C O   1 
ATOM   11813 C CB  . ILE C 3 739 ? 245.211 168.276 106.501 1.00 356.44 ? 783 ILE C CB  1 
ATOM   11814 C CG1 . ILE C 3 739 ? 245.791 168.950 107.745 1.00 356.44 ? 783 ILE C CG1 1 
ATOM   11815 C CG2 . ILE C 3 739 ? 244.842 166.830 106.794 1.00 356.44 ? 783 ILE C CG2 1 
ATOM   11816 C CD1 . ILE C 3 739 ? 244.741 169.475 108.700 1.00 356.44 ? 783 ILE C CD1 1 
ATOM   11817 N N   . LYS C 3 740 ? 245.377 170.049 103.827 1.00 338.82 ? 784 LYS C N   1 
ATOM   11818 C CA  . LYS C 3 740 ? 245.307 171.347 103.175 1.00 338.82 ? 784 LYS C CA  1 
ATOM   11819 C C   . LYS C 3 740 ? 243.973 172.012 103.487 1.00 338.82 ? 784 LYS C C   1 
ATOM   11820 O O   . LYS C 3 740 ? 242.949 171.341 103.648 1.00 338.82 ? 784 LYS C O   1 
ATOM   11821 C CB  . LYS C 3 740 ? 245.486 171.218 101.657 1.00 338.82 ? 784 LYS C CB  1 
ATOM   11822 C CG  . LYS C 3 740 ? 246.605 170.275 101.242 1.00 338.82 ? 784 LYS C CG  1 
ATOM   11823 C CD  . LYS C 3 740 ? 247.947 170.731 101.792 1.00 338.82 ? 784 LYS C CD  1 
ATOM   11824 C CE  . LYS C 3 740 ? 249.012 169.662 101.605 1.00 338.82 ? 784 LYS C CE  1 
ATOM   11825 N NZ  . LYS C 3 740 ? 249.180 169.286 100.175 1.00 338.82 ? 784 LYS C NZ  1 
ATOM   11826 N N   . VAL C 3 741 ? 243.996 173.339 103.573 1.00 332.01 ? 785 VAL C N   1 
ATOM   11827 C CA  . VAL C 3 741 ? 242.815 174.137 103.881 1.00 332.01 ? 785 VAL C CA  1 
ATOM   11828 C C   . VAL C 3 741 ? 242.557 175.070 102.707 1.00 332.01 ? 785 VAL C C   1 
ATOM   11829 O O   . VAL C 3 741 ? 243.400 175.916 102.382 1.00 332.01 ? 785 VAL C O   1 
ATOM   11830 C CB  . VAL C 3 741 ? 242.987 174.932 105.185 1.00 332.01 ? 785 VAL C CB  1 
ATOM   11831 C CG1 . VAL C 3 741 ? 241.773 175.817 105.430 1.00 332.01 ? 785 VAL C CG1 1 
ATOM   11832 C CG2 . VAL C 3 741 ? 243.216 173.989 106.356 1.00 332.01 ? 785 VAL C CG2 1 
ATOM   11833 N N   . LYS C 3 742 ? 241.395 174.918 102.074 1.00 330.31 ? 786 LYS C N   1 
ATOM   11834 C CA  . LYS C 3 742 ? 240.995 175.747 100.941 1.00 330.31 ? 786 LYS C CA  1 
ATOM   11835 C C   . LYS C 3 742 ? 239.614 176.319 101.231 1.00 330.31 ? 786 LYS C C   1 
ATOM   11836 O O   . LYS C 3 742 ? 238.621 175.583 101.230 1.00 330.31 ? 786 LYS C O   1 
ATOM   11837 C CB  . LYS C 3 742 ? 240.995 174.944 99.640  1.00 330.31 ? 786 LYS C CB  1 
ATOM   11838 C CG  . LYS C 3 742 ? 242.370 174.455 99.216  1.00 330.31 ? 786 LYS C CG  1 
ATOM   11839 C CD  . LYS C 3 742 ? 243.342 175.614 99.059  1.00 330.31 ? 786 LYS C CD  1 
ATOM   11840 C CE  . LYS C 3 742 ? 244.733 175.123 98.696  1.00 330.31 ? 786 LYS C CE  1 
ATOM   11841 N NZ  . LYS C 3 742 ? 245.701 176.247 98.565  1.00 330.31 ? 786 LYS C NZ  1 
ATOM   11842 N N   . ASN C 3 743 ? 239.551 177.624 101.476 1.00 330.48 ? 787 ASN C N   1 
ATOM   11843 C CA  . ASN C 3 743 ? 238.298 178.291 101.797 1.00 330.48 ? 787 ASN C CA  1 
ATOM   11844 C C   . ASN C 3 743 ? 237.578 178.716 100.523 1.00 330.48 ? 787 ASN C C   1 
ATOM   11845 O O   . ASN C 3 743 ? 238.202 179.190 99.569  1.00 330.48 ? 787 ASN C O   1 
ATOM   11846 C CB  . ASN C 3 743 ? 238.548 179.510 102.687 1.00 330.48 ? 787 ASN C CB  1 
ATOM   11847 C CG  . ASN C 3 743 ? 239.500 180.508 102.056 1.00 330.48 ? 787 ASN C CG  1 
ATOM   11848 O OD1 . ASN C 3 743 ? 240.385 180.137 101.284 1.00 330.48 ? 787 ASN C OD1 1 
ATOM   11849 N ND2 . ASN C 3 743 ? 239.323 181.783 102.382 1.00 330.48 ? 787 ASN C ND2 1 
ATOM   11850 N N   . ILE C 3 744 ? 236.260 178.538 100.516 1.00 339.54 ? 788 ILE C N   1 
ATOM   11851 C CA  . ILE C 3 744 ? 235.410 178.922 99.394  1.00 339.54 ? 788 ILE C CA  1 
ATOM   11852 C C   . ILE C 3 744 ? 234.419 179.948 99.927  1.00 339.54 ? 788 ILE C C   1 
ATOM   11853 O O   . ILE C 3 744 ? 233.427 179.591 100.575 1.00 339.54 ? 788 ILE C O   1 
ATOM   11854 C CB  . ILE C 3 744 ? 234.691 177.721 98.769  1.00 339.54 ? 788 ILE C CB  1 
ATOM   11855 C CG1 . ILE C 3 744 ? 235.708 176.720 98.217  1.00 339.54 ? 788 ILE C CG1 1 
ATOM   11856 C CG2 . ILE C 3 744 ? 233.746 178.178 97.668  1.00 339.54 ? 788 ILE C CG2 1 
ATOM   11857 C CD1 . ILE C 3 744 ? 236.518 177.250 97.054  1.00 339.54 ? 788 ILE C CD1 1 
ATOM   11858 N N   . THR C 3 745 ? 234.684 181.227 99.663  1.00 337.27 ? 789 THR C N   1 
ATOM   11859 C CA  . THR C 3 745 ? 233.816 182.299 100.132 1.00 337.27 ? 789 THR C CA  1 
ATOM   11860 C C   . THR C 3 745 ? 232.601 182.516 99.240  1.00 337.27 ? 789 THR C C   1 
ATOM   11861 O O   . THR C 3 745 ? 231.738 183.330 99.586  1.00 337.27 ? 789 THR C O   1 
ATOM   11862 C CB  . THR C 3 745 ? 234.604 183.607 100.241 1.00 337.27 ? 789 THR C CB  1 
ATOM   11863 O OG1 . THR C 3 745 ? 235.276 183.868 99.003  1.00 337.27 ? 789 THR C OG1 1 
ATOM   11864 C CG2 . THR C 3 745 ? 235.630 183.517 101.360 1.00 337.27 ? 789 THR C CG2 1 
ATOM   11865 N N   . ASP C 3 746 ? 232.510 181.816 98.112  1.00 351.02 ? 790 ASP C N   1 
ATOM   11866 C CA  . ASP C 3 746 ? 231.381 181.961 97.200  1.00 351.02 ? 790 ASP C CA  1 
ATOM   11867 C C   . ASP C 3 746 ? 230.198 181.171 97.746  1.00 351.02 ? 790 ASP C C   1 
ATOM   11868 O O   . ASP C 3 746 ? 230.230 179.936 97.782  1.00 351.02 ? 790 ASP C O   1 
ATOM   11869 C CB  . ASP C 3 746 ? 231.762 181.487 95.801  1.00 351.02 ? 790 ASP C CB  1 
ATOM   11870 C CG  . ASP C 3 746 ? 233.103 182.028 95.348  1.00 351.02 ? 790 ASP C CG  1 
ATOM   11871 O OD1 . ASP C 3 746 ? 233.150 183.182 94.872  1.00 351.02 ? 790 ASP C OD1 1 
ATOM   11872 O OD2 . ASP C 3 746 ? 234.110 181.300 95.468  1.00 351.02 ? 790 ASP C OD2 1 
ATOM   11873 N N   . ILE C 3 747 ? 229.151 181.880 98.175  1.00 337.23 ? 791 ILE C N   1 
ATOM   11874 C CA  . ILE C 3 747 ? 227.978 181.214 98.725  1.00 337.23 ? 791 ILE C CA  1 
ATOM   11875 C C   . ILE C 3 747 ? 227.155 180.533 97.638  1.00 337.23 ? 791 ILE C C   1 
ATOM   11876 O O   . ILE C 3 747 ? 226.394 179.604 97.933  1.00 337.23 ? 791 ILE C O   1 
ATOM   11877 C CB  . ILE C 3 747 ? 227.122 182.216 99.524  1.00 337.23 ? 791 ILE C CB  1 
ATOM   11878 C CG1 . ILE C 3 747 ? 226.168 181.479 100.467 1.00 337.23 ? 791 ILE C CG1 1 
ATOM   11879 C CG2 . ILE C 3 747 ? 226.357 183.145 98.590  1.00 337.23 ? 791 ILE C CG2 1 
ATOM   11880 C CD1 . ILE C 3 747 ? 226.859 180.498 101.389 1.00 337.23 ? 791 ILE C CD1 1 
ATOM   11881 N N   . SER C 3 748 ? 227.289 180.965 96.384  1.00 355.87 ? 792 SER C N   1 
ATOM   11882 C CA  . SER C 3 748 ? 226.543 180.365 95.286  1.00 355.87 ? 792 SER C CA  1 
ATOM   11883 C C   . SER C 3 748 ? 227.263 179.185 94.649  1.00 355.87 ? 792 SER C C   1 
ATOM   11884 O O   . SER C 3 748 ? 226.615 178.367 93.988  1.00 355.87 ? 792 SER C O   1 
ATOM   11885 C CB  . SER C 3 748 ? 226.245 181.417 94.213  1.00 355.87 ? 792 SER C CB  1 
ATOM   11886 O OG  . SER C 3 748 ? 227.312 181.518 93.286  1.00 355.87 ? 792 SER C OG  1 
ATOM   11887 N N   . GLN C 3 749 ? 228.577 179.080 94.830  1.00 368.93 ? 793 GLN C N   1 
ATOM   11888 C CA  . GLN C 3 749 ? 229.351 177.974 94.276  1.00 368.93 ? 793 GLN C CA  1 
ATOM   11889 C C   . GLN C 3 749 ? 229.151 176.739 95.147  1.00 368.93 ? 793 GLN C C   1 
ATOM   11890 O O   . GLN C 3 749 ? 229.690 176.659 96.257  1.00 368.93 ? 793 GLN C O   1 
ATOM   11891 C CB  . GLN C 3 749 ? 230.827 178.351 94.187  1.00 368.93 ? 793 GLN C CB  1 
ATOM   11892 C CG  . GLN C 3 749 ? 231.730 177.240 93.678  1.00 368.93 ? 793 GLN C CG  1 
ATOM   11893 C CD  . GLN C 3 749 ? 231.528 176.948 92.205  1.00 368.93 ? 793 GLN C CD  1 
ATOM   11894 O OE1 . GLN C 3 749 ? 231.021 177.785 91.458  1.00 368.93 ? 793 GLN C OE1 1 
ATOM   11895 N NE2 . GLN C 3 749 ? 231.930 175.757 91.777  1.00 368.93 ? 793 GLN C NE2 1 
ATOM   11896 N N   . LYS C 3 750 ? 228.380 175.775 94.647  1.00 374.05 ? 794 LYS C N   1 
ATOM   11897 C CA  . LYS C 3 750 ? 228.126 174.527 95.352  1.00 374.05 ? 794 LYS C CA  1 
ATOM   11898 C C   . LYS C 3 750 ? 228.953 173.367 94.816  1.00 374.05 ? 794 LYS C C   1 
ATOM   11899 O O   . LYS C 3 750 ? 228.845 172.253 95.341  1.00 374.05 ? 794 LYS C O   1 
ATOM   11900 C CB  . LYS C 3 750 ? 226.636 174.169 95.278  1.00 374.05 ? 794 LYS C CB  1 
ATOM   11901 C CG  . LYS C 3 750 ? 225.701 175.239 95.825  1.00 374.05 ? 794 LYS C CG  1 
ATOM   11902 C CD  . LYS C 3 750 ? 225.947 175.501 97.305  1.00 374.05 ? 794 LYS C CD  1 
ATOM   11903 C CE  . LYS C 3 750 ? 224.996 176.557 97.843  1.00 374.05 ? 794 LYS C CE  1 
ATOM   11904 N NZ  . LYS C 3 750 ? 225.223 176.838 99.289  1.00 374.05 ? 794 LYS C NZ  1 
ATOM   11905 N N   . THR C 3 751 ? 229.776 173.599 93.798  1.00 366.17 ? 795 THR C N   1 
ATOM   11906 C CA  . THR C 3 751 ? 230.582 172.562 93.171  1.00 366.17 ? 795 THR C CA  1 
ATOM   11907 C C   . THR C 3 751 ? 232.058 172.816 93.449  1.00 366.17 ? 795 THR C C   1 
ATOM   11908 O O   . THR C 3 751 ? 232.531 173.953 93.351  1.00 366.17 ? 795 THR C O   1 
ATOM   11909 C CB  . THR C 3 751 ? 230.339 172.516 91.658  1.00 366.17 ? 795 THR C CB  1 
ATOM   11910 O OG1 . THR C 3 751 ? 228.941 172.683 91.394  1.00 366.17 ? 795 THR C OG1 1 
ATOM   11911 C CG2 . THR C 3 751 ? 230.800 171.184 91.084  1.00 366.17 ? 795 THR C CG2 1 
ATOM   11912 N N   . LEU C 3 752 ? 232.782 171.752 93.789  1.00 324.83 ? 796 LEU C N   1 
ATOM   11913 C CA  . LEU C 3 752 ? 234.195 171.854 94.132  1.00 324.83 ? 796 LEU C CA  1 
ATOM   11914 C C   . LEU C 3 752 ? 234.944 170.676 93.528  1.00 324.83 ? 796 LEU C C   1 
ATOM   11915 O O   . LEU C 3 752 ? 234.507 169.529 93.654  1.00 324.83 ? 796 LEU C O   1 
ATOM   11916 C CB  . LEU C 3 752 ? 234.387 171.900 95.656  1.00 324.83 ? 796 LEU C CB  1 
ATOM   11917 C CG  . LEU C 3 752 ? 235.794 171.833 96.261  1.00 324.83 ? 796 LEU C CG  1 
ATOM   11918 C CD1 . LEU C 3 752 ? 235.837 172.629 97.555  1.00 324.83 ? 796 LEU C CD1 1 
ATOM   11919 C CD2 . LEU C 3 752 ? 236.231 170.398 96.526  1.00 324.83 ? 796 LEU C CD2 1 
ATOM   11920 N N   . ARG C 3 753 ? 236.071 170.966 92.880  1.00 274.74 ? 797 ARG C N   1 
ATOM   11921 C CA  . ARG C 3 753 ? 236.926 169.952 92.279  1.00 274.74 ? 797 ARG C CA  1 
ATOM   11922 C C   . ARG C 3 753 ? 238.371 170.208 92.682  1.00 274.74 ? 797 ARG C C   1 
ATOM   11923 O O   . ARG C 3 753 ? 238.795 171.361 92.802  1.00 274.74 ? 797 ARG C O   1 
ATOM   11924 C CB  . ARG C 3 753 ? 236.799 169.947 90.748  1.00 274.74 ? 797 ARG C CB  1 
ATOM   11925 C CG  . ARG C 3 753 ? 236.995 171.312 90.103  1.00 274.74 ? 797 ARG C CG  1 
ATOM   11926 C CD  . ARG C 3 753 ? 236.783 171.257 88.597  1.00 274.74 ? 797 ARG C CD  1 
ATOM   11927 N NE  . ARG C 3 753 ? 235.389 171.001 88.246  1.00 274.74 ? 797 ARG C NE  1 
ATOM   11928 C CZ  . ARG C 3 753 ? 234.931 169.833 87.809  1.00 274.74 ? 797 ARG C CZ  1 
ATOM   11929 N NH1 . ARG C 3 753 ? 235.756 168.805 87.665  1.00 274.74 ? 797 ARG C NH1 1 
ATOM   11930 N NH2 . ARG C 3 753 ? 233.646 169.691 87.514  1.00 274.74 ? 797 ARG C NH2 1 
ATOM   11931 N N   . ILE C 3 754 ? 239.121 169.129 92.895  1.00 220.44 ? 798 ILE C N   1 
ATOM   11932 C CA  . ILE C 3 754 ? 240.520 169.202 93.301  1.00 220.44 ? 798 ILE C CA  1 
ATOM   11933 C C   . ILE C 3 754 ? 241.363 168.503 92.244  1.00 220.44 ? 798 ILE C C   1 
ATOM   11934 O O   . ILE C 3 754 ? 241.064 167.367 91.856  1.00 220.44 ? 798 ILE C O   1 
ATOM   11935 C CB  . ILE C 3 754 ? 240.745 168.567 94.685  1.00 220.44 ? 798 ILE C CB  1 
ATOM   11936 C CG1 . ILE C 3 754 ? 239.812 169.199 95.720  1.00 220.44 ? 798 ILE C CG1 1 
ATOM   11937 C CG2 . ILE C 3 754 ? 242.197 168.721 95.111  1.00 220.44 ? 798 ILE C CG2 1 
ATOM   11938 C CD1 . ILE C 3 754 ? 239.996 170.689 95.875  1.00 220.44 ? 798 ILE C CD1 1 
ATOM   11939 N N   . ALA C 3 755 ? 242.413 169.176 91.786  1.00 195.79 ? 799 ALA C N   1 
ATOM   11940 C CA  . ALA C 3 755 ? 243.311 168.661 90.764  1.00 195.79 ? 799 ALA C CA  1 
ATOM   11941 C C   . ALA C 3 755 ? 244.649 168.282 91.391  1.00 195.79 ? 799 ALA C C   1 
ATOM   11942 O O   . ALA C 3 755 ? 244.864 168.438 92.597  1.00 195.79 ? 799 ALA C O   1 
ATOM   11943 C CB  . ALA C 3 755 ? 243.498 169.687 89.645  1.00 195.79 ? 799 ALA C CB  1 
ATOM   11944 N N   . ASP C 3 756 ? 245.553 167.779 90.548  1.00 230.11 ? 800 ASP C N   1 
ATOM   11945 C CA  . ASP C 3 756 ? 246.883 167.339 90.968  1.00 230.11 ? 800 ASP C CA  1 
ATOM   11946 C C   . ASP C 3 756 ? 246.778 166.280 92.068  1.00 230.11 ? 800 ASP C C   1 
ATOM   11947 O O   . ASP C 3 756 ? 247.231 166.464 93.200  1.00 230.11 ? 800 ASP C O   1 
ATOM   11948 C CB  . ASP C 3 756 ? 247.737 168.529 91.420  1.00 230.11 ? 800 ASP C CB  1 
ATOM   11949 C CG  . ASP C 3 756 ? 248.096 169.456 90.276  1.00 230.11 ? 800 ASP C CG  1 
ATOM   11950 O OD1 . ASP C 3 756 ? 248.195 168.975 89.128  1.00 230.11 ? 800 ASP C OD1 1 
ATOM   11951 O OD2 . ASP C 3 756 ? 248.280 170.665 90.526  1.00 230.11 ? 800 ASP C OD2 1 
ATOM   11952 N N   . LEU C 3 757 ? 246.165 165.156 91.707  1.00 294.13 ? 801 LEU C N   1 
ATOM   11953 C CA  . LEU C 3 757 ? 245.851 164.093 92.646  1.00 294.13 ? 801 LEU C CA  1 
ATOM   11954 C C   . LEU C 3 757 ? 246.529 162.799 92.215  1.00 294.13 ? 801 LEU C C   1 
ATOM   11955 O O   . LEU C 3 757 ? 246.705 162.538 91.021  1.00 294.13 ? 801 LEU C O   1 
ATOM   11956 C CB  . LEU C 3 757 ? 244.333 163.883 92.746  1.00 294.13 ? 801 LEU C CB  1 
ATOM   11957 C CG  . LEU C 3 757 ? 243.828 162.891 93.792  1.00 294.13 ? 801 LEU C CG  1 
ATOM   11958 C CD1 . LEU C 3 757 ? 244.550 163.125 95.104  1.00 294.13 ? 801 LEU C CD1 1 
ATOM   11959 C CD2 . LEU C 3 757 ? 242.330 163.020 93.976  1.00 294.13 ? 801 LEU C CD2 1 
ATOM   11960 N N   . GLN C 3 758 ? 246.906 161.990 93.201  1.00 327.58 ? 802 GLN C N   1 
ATOM   11961 C CA  . GLN C 3 758 ? 247.554 160.709 92.969  1.00 327.58 ? 802 GLN C CA  1 
ATOM   11962 C C   . GLN C 3 758 ? 246.577 159.566 93.222  1.00 327.58 ? 802 GLN C C   1 
ATOM   11963 O O   . GLN C 3 758 ? 245.571 159.725 93.918  1.00 327.58 ? 802 GLN C O   1 
ATOM   11964 C CB  . GLN C 3 758 ? 248.787 160.555 93.863  1.00 327.58 ? 802 GLN C CB  1 
ATOM   11965 C CG  . GLN C 3 758 ? 249.956 161.505 93.562  1.00 327.58 ? 802 GLN C CG  1 
ATOM   11966 C CD  . GLN C 3 758 ? 250.379 161.540 92.096  1.00 327.58 ? 802 GLN C CD  1 
ATOM   11967 O OE1 . GLN C 3 758 ? 249.630 161.972 91.218  1.00 327.58 ? 802 GLN C OE1 1 
ATOM   11968 N NE2 . GLN C 3 758 ? 251.594 161.075 91.830  1.00 327.58 ? 802 GLN C NE2 1 
ATOM   11969 N N   . GLY C 3 759 ? 246.886 158.405 92.642  1.00 331.54 ? 803 GLY C N   1 
ATOM   11970 C CA  . GLY C 3 759 ? 245.992 157.274 92.736  1.00 331.54 ? 803 GLY C CA  1 
ATOM   11971 C C   . GLY C 3 759 ? 246.301 156.358 93.907  1.00 331.54 ? 803 GLY C C   1 
ATOM   11972 O O   . GLY C 3 759 ? 247.398 156.362 94.465  1.00 331.54 ? 803 GLY C O   1 
ATOM   11973 N N   . LYS C 3 760 ? 245.293 155.564 94.270  1.00 335.84 ? 804 LYS C N   1 
ATOM   11974 C CA  . LYS C 3 760 ? 245.402 154.545 95.315  1.00 335.84 ? 804 LYS C CA  1 
ATOM   11975 C C   . LYS C 3 760 ? 245.887 155.154 96.631  1.00 335.84 ? 804 LYS C C   1 
ATOM   11976 O O   . LYS C 3 760 ? 246.837 154.682 97.259  1.00 335.84 ? 804 LYS C O   1 
ATOM   11977 C CB  . LYS C 3 760 ? 246.307 153.394 94.864  1.00 335.84 ? 804 LYS C CB  1 
ATOM   11978 C CG  . LYS C 3 760 ? 246.185 152.115 95.697  1.00 335.84 ? 804 LYS C CG  1 
ATOM   11979 C CD  . LYS C 3 760 ? 244.751 151.602 95.787  1.00 335.84 ? 804 LYS C CD  1 
ATOM   11980 C CE  . LYS C 3 760 ? 244.130 151.387 94.413  1.00 335.84 ? 804 LYS C CE  1 
ATOM   11981 N NZ  . LYS C 3 760 ? 242.657 151.177 94.499  1.00 335.84 ? 804 LYS C NZ  1 
ATOM   11982 N N   . THR C 3 761 ? 245.228 156.236 97.040  1.00 335.16 ? 805 THR C N   1 
ATOM   11983 C CA  . THR C 3 761 ? 245.521 156.901 98.303  1.00 335.16 ? 805 THR C CA  1 
ATOM   11984 C C   . THR C 3 761 ? 244.208 157.261 98.979  1.00 335.16 ? 805 THR C C   1 
ATOM   11985 O O   . THR C 3 761 ? 243.353 157.913 98.370  1.00 335.16 ? 805 THR C O   1 
ATOM   11986 C CB  . THR C 3 761 ? 246.380 158.151 98.089  1.00 335.16 ? 805 THR C CB  1 
ATOM   11987 O OG1 . THR C 3 761 ? 247.407 157.869 97.130  1.00 335.16 ? 805 THR C OG1 1 
ATOM   11988 C CG2 . THR C 3 761 ? 247.023 158.579 99.399  1.00 335.16 ? 805 THR C CG2 1 
ATOM   11989 N N   . SER C 3 762 ? 244.045 156.830 100.228 1.00 338.81 ? 806 SER C N   1 
ATOM   11990 C CA  . SER C 3 762 ? 242.827 157.095 100.986 1.00 338.81 ? 806 SER C CA  1 
ATOM   11991 C C   . SER C 3 762 ? 242.919 158.484 101.607 1.00 338.81 ? 806 SER C C   1 
ATOM   11992 O O   . SER C 3 762 ? 243.839 158.767 102.381 1.00 338.81 ? 806 SER C O   1 
ATOM   11993 C CB  . SER C 3 762 ? 242.623 156.026 102.057 1.00 338.81 ? 806 SER C CB  1 
ATOM   11994 O OG  . SER C 3 762 ? 241.283 156.015 102.517 1.00 338.81 ? 806 SER C OG  1 
ATOM   11995 N N   . TYR C 3 763 ? 241.969 159.351 101.267 1.00 352.66 ? 807 TYR C N   1 
ATOM   11996 C CA  . TYR C 3 763 ? 241.938 160.723 101.752 1.00 352.66 ? 807 TYR C CA  1 
ATOM   11997 C C   . TYR C 3 763 ? 240.767 160.924 102.704 1.00 352.66 ? 807 TYR C C   1 
ATOM   11998 O O   . TYR C 3 763 ? 239.737 160.251 102.590 1.00 352.66 ? 807 TYR C O   1 
ATOM   11999 C CB  . TYR C 3 763 ? 241.843 161.710 100.586 1.00 352.66 ? 807 TYR C CB  1 
ATOM   12000 C CG  . TYR C 3 763 ? 243.098 161.771 99.750  1.00 352.66 ? 807 TYR C CG  1 
ATOM   12001 C CD1 . TYR C 3 763 ? 244.180 162.548 100.143 1.00 352.66 ? 807 TYR C CD1 1 
ATOM   12002 C CD2 . TYR C 3 763 ? 243.213 161.032 98.582  1.00 352.66 ? 807 TYR C CD2 1 
ATOM   12003 C CE1 . TYR C 3 763 ? 245.331 162.604 99.384  1.00 352.66 ? 807 TYR C CE1 1 
ATOM   12004 C CE2 . TYR C 3 763 ? 244.360 161.078 97.820  1.00 352.66 ? 807 TYR C CE2 1 
ATOM   12005 C CZ  . TYR C 3 763 ? 245.419 161.864 98.225  1.00 352.66 ? 807 TYR C CZ  1 
ATOM   12006 O OH  . TYR C 3 763 ? 246.565 161.913 97.467  1.00 352.66 ? 807 TYR C OH  1 
ATOM   12007 N N   . HIS C 3 764 ? 240.933 161.855 103.640 1.00 374.06 ? 808 HIS C N   1 
ATOM   12008 C CA  . HIS C 3 764 ? 239.907 162.186 104.622 1.00 374.06 ? 808 HIS C CA  1 
ATOM   12009 C C   . HIS C 3 764 ? 239.310 163.540 104.256 1.00 374.06 ? 808 HIS C C   1 
ATOM   12010 O O   . HIS C 3 764 ? 239.935 164.583 104.478 1.00 374.06 ? 808 HIS C O   1 
ATOM   12011 C CB  . HIS C 3 764 ? 240.497 162.203 106.031 1.00 374.06 ? 808 HIS C CB  1 
ATOM   12012 C CG  . HIS C 3 764 ? 239.478 162.042 107.116 1.00 374.06 ? 808 HIS C CG  1 
ATOM   12013 N ND1 . HIS C 3 764 ? 239.740 162.353 108.433 1.00 374.06 ? 808 HIS C ND1 1 
ATOM   12014 C CD2 . HIS C 3 764 ? 238.198 161.602 107.081 1.00 374.06 ? 808 HIS C CD2 1 
ATOM   12015 C CE1 . HIS C 3 764 ? 238.666 162.111 109.163 1.00 374.06 ? 808 HIS C CE1 1 
ATOM   12016 N NE2 . HIS C 3 764 ? 237.716 161.654 108.367 1.00 374.06 ? 808 HIS C NE2 1 
ATOM   12017 N N   . LEU C 3 765 ? 238.104 163.523 103.695 1.00 381.74 ? 809 LEU C N   1 
ATOM   12018 C CA  . LEU C 3 765 ? 237.426 164.742 103.271 1.00 381.74 ? 809 LEU C CA  1 
ATOM   12019 C C   . LEU C 3 765 ? 236.578 165.273 104.420 1.00 381.74 ? 809 LEU C C   1 
ATOM   12020 O O   . LEU C 3 765 ? 235.700 164.567 104.929 1.00 381.74 ? 809 LEU C O   1 
ATOM   12021 C CB  . LEU C 3 765 ? 236.557 164.485 102.038 1.00 381.74 ? 809 LEU C CB  1 
ATOM   12022 C CG  . LEU C 3 765 ? 237.229 163.977 100.758 1.00 381.74 ? 809 LEU C CG  1 
ATOM   12023 C CD1 . LEU C 3 765 ? 237.368 162.460 100.757 1.00 381.74 ? 809 LEU C CD1 1 
ATOM   12024 C CD2 . LEU C 3 765 ? 236.459 164.447 99.531  1.00 381.74 ? 809 LEU C CD2 1 
ATOM   12025 N N   . VAL C 3 766 ? 236.838 166.514 104.823 1.00 388.44 ? 810 VAL C N   1 
ATOM   12026 C CA  . VAL C 3 766 ? 236.130 167.160 105.922 1.00 388.44 ? 810 VAL C CA  1 
ATOM   12027 C C   . VAL C 3 766 ? 235.585 168.492 105.424 1.00 388.44 ? 810 VAL C C   1 
ATOM   12028 O O   . VAL C 3 766 ? 236.324 169.288 104.833 1.00 388.44 ? 810 VAL C O   1 
ATOM   12029 C CB  . VAL C 3 766 ? 237.044 167.365 107.144 1.00 388.44 ? 810 VAL C CB  1 
ATOM   12030 C CG1 . VAL C 3 766 ? 236.330 168.174 108.215 1.00 388.44 ? 810 VAL C CG1 1 
ATOM   12031 C CG2 . VAL C 3 766 ? 237.501 166.024 107.697 1.00 388.44 ? 810 VAL C CG2 1 
ATOM   12032 N N   . LEU C 3 767 ? 234.297 168.732 105.665 1.00 383.63 ? 811 LEU C N   1 
ATOM   12033 C CA  . LEU C 3 767 ? 233.637 169.972 105.274 1.00 383.63 ? 811 LEU C CA  1 
ATOM   12034 C C   . LEU C 3 767 ? 233.019 170.596 106.516 1.00 383.63 ? 811 LEU C C   1 
ATOM   12035 O O   . LEU C 3 767 ? 232.233 169.946 107.212 1.00 383.63 ? 811 LEU C O   1 
ATOM   12036 C CB  . LEU C 3 767 ? 232.570 169.721 104.205 1.00 383.63 ? 811 LEU C CB  1 
ATOM   12037 C CG  . LEU C 3 767 ? 231.677 170.896 103.792 1.00 383.63 ? 811 LEU C CG  1 
ATOM   12038 C CD1 . LEU C 3 767 ? 232.494 172.162 103.562 1.00 383.63 ? 811 LEU C CD1 1 
ATOM   12039 C CD2 . LEU C 3 767 ? 230.868 170.545 102.552 1.00 383.63 ? 811 LEU C CD2 1 
ATOM   12040 N N   . ARG C 3 768 ? 233.370 171.850 106.787 1.00 348.83 ? 812 ARG C N   1 
ATOM   12041 C CA  . ARG C 3 768 ? 232.903 172.559 107.970 1.00 348.83 ? 812 ARG C CA  1 
ATOM   12042 C C   . ARG C 3 768 ? 232.438 173.951 107.572 1.00 348.83 ? 812 ARG C C   1 
ATOM   12043 O O   . ARG C 3 768 ? 233.170 174.684 106.899 1.00 348.83 ? 812 ARG C O   1 
ATOM   12044 C CB  . ARG C 3 768 ? 234.007 172.650 109.029 1.00 348.83 ? 812 ARG C CB  1 
ATOM   12045 C CG  . ARG C 3 768 ? 233.533 173.148 110.382 1.00 348.83 ? 812 ARG C CG  1 
ATOM   12046 C CD  . ARG C 3 768 ? 234.591 172.928 111.451 1.00 348.83 ? 812 ARG C CD  1 
ATOM   12047 N NE  . ARG C 3 768 ? 234.085 173.223 112.789 1.00 348.83 ? 812 ARG C NE  1 
ATOM   12048 C CZ  . ARG C 3 768 ? 234.791 173.074 113.904 1.00 348.83 ? 812 ARG C CZ  1 
ATOM   12049 N NH1 . ARG C 3 768 ? 236.040 172.632 113.847 1.00 348.83 ? 812 ARG C NH1 1 
ATOM   12050 N NH2 . ARG C 3 768 ? 234.249 173.367 115.079 1.00 348.83 ? 812 ARG C NH2 1 
ATOM   12051 N N   . ALA C 3 769 ? 231.228 174.309 107.987 1.00 306.82 ? 813 ALA C N   1 
ATOM   12052 C CA  . ALA C 3 769 ? 230.676 175.624 107.707 1.00 306.82 ? 813 ALA C CA  1 
ATOM   12053 C C   . ALA C 3 769 ? 231.019 176.593 108.831 1.00 306.82 ? 813 ALA C C   1 
ATOM   12054 O O   . ALA C 3 769 ? 231.125 176.210 109.999 1.00 306.82 ? 813 ALA C O   1 
ATOM   12055 C CB  . ALA C 3 769 ? 229.159 175.549 107.527 1.00 306.82 ? 813 ALA C CB  1 
ATOM   12056 N N   . TYR C 3 770 ? 231.192 177.861 108.464 1.00 314.04 ? 814 TYR C N   1 
ATOM   12057 C CA  . TYR C 3 770 ? 231.547 178.908 109.411 1.00 314.04 ? 814 TYR C CA  1 
ATOM   12058 C C   . TYR C 3 770 ? 230.687 180.137 109.162 1.00 314.04 ? 814 TYR C C   1 
ATOM   12059 O O   . TYR C 3 770 ? 230.346 180.447 108.016 1.00 314.04 ? 814 TYR C O   1 
ATOM   12060 C CB  . TYR C 3 770 ? 233.036 179.274 109.305 1.00 314.04 ? 814 TYR C CB  1 
ATOM   12061 C CG  . TYR C 3 770 ? 233.386 180.104 108.089 1.00 314.04 ? 814 TYR C CG  1 
ATOM   12062 C CD1 . TYR C 3 770 ? 233.442 179.532 106.825 1.00 314.04 ? 814 TYR C CD1 1 
ATOM   12063 C CD2 . TYR C 3 770 ? 233.667 181.460 108.207 1.00 314.04 ? 814 TYR C CD2 1 
ATOM   12064 C CE1 . TYR C 3 770 ? 233.764 180.286 105.712 1.00 314.04 ? 814 TYR C CE1 1 
ATOM   12065 C CE2 . TYR C 3 770 ? 233.990 182.222 107.100 1.00 314.04 ? 814 TYR C CE2 1 
ATOM   12066 C CZ  . TYR C 3 770 ? 234.037 181.630 105.855 1.00 314.04 ? 814 TYR C CZ  1 
ATOM   12067 O OH  . TYR C 3 770 ? 234.358 182.385 104.750 1.00 314.04 ? 814 TYR C OH  1 
ATOM   12068 N N   . THR C 3 771 ? 230.336 180.831 110.243 1.00 305.21 ? 815 THR C N   1 
ATOM   12069 C CA  . THR C 3 771 ? 229.535 182.046 110.151 1.00 305.21 ? 815 THR C CA  1 
ATOM   12070 C C   . THR C 3 771 ? 230.174 183.167 110.961 1.00 305.21 ? 815 THR C C   1 
ATOM   12071 O O   . THR C 3 771 ? 231.288 183.014 111.472 1.00 305.21 ? 815 THR C O   1 
ATOM   12072 C CB  . THR C 3 771 ? 228.105 181.792 110.636 1.00 305.21 ? 815 THR C CB  1 
ATOM   12073 O OG1 . THR C 3 771 ? 228.139 181.137 111.911 1.00 305.21 ? 815 THR C OG1 1 
ATOM   12074 C CG2 . THR C 3 771 ? 227.347 180.924 109.642 1.00 305.21 ? 815 THR C CG2 1 
ATOM   12075 N N   . ASP C 3 772 ? 229.476 184.299 111.082 1.00 298.23 ? 816 ASP C N   1 
ATOM   12076 C CA  . ASP C 3 772 ? 230.010 185.412 111.859 1.00 298.23 ? 816 ASP C CA  1 
ATOM   12077 C C   . ASP C 3 772 ? 229.959 185.131 113.355 1.00 298.23 ? 816 ASP C C   1 
ATOM   12078 O O   . ASP C 3 772 ? 230.834 185.587 114.100 1.00 298.23 ? 816 ASP C O   1 
ATOM   12079 C CB  . ASP C 3 772 ? 229.246 186.695 111.534 1.00 298.23 ? 816 ASP C CB  1 
ATOM   12080 C CG  . ASP C 3 772 ? 229.587 187.245 110.164 1.00 298.23 ? 816 ASP C CG  1 
ATOM   12081 O OD1 . ASP C 3 772 ? 230.507 186.702 109.516 1.00 298.23 ? 816 ASP C OD1 1 
ATOM   12082 O OD2 . ASP C 3 772 ? 228.934 188.219 109.733 1.00 298.23 ? 816 ASP C OD2 1 
ATOM   12083 N N   . GLY C 3 773 ? 228.954 184.390 113.811 1.00 294.57 ? 817 GLY C N   1 
ATOM   12084 C CA  . GLY C 3 773 ? 228.795 184.062 115.210 1.00 294.57 ? 817 GLY C CA  1 
ATOM   12085 C C   . GLY C 3 773 ? 229.497 182.802 115.665 1.00 294.57 ? 817 GLY C C   1 
ATOM   12086 O O   . GLY C 3 773 ? 229.306 182.384 116.812 1.00 294.57 ? 817 GLY C O   1 
ATOM   12087 N N   . GLY C 3 774 ? 230.303 182.181 114.808 1.00 293.99 ? 818 GLY C N   1 
ATOM   12088 C CA  . GLY C 3 774 ? 231.013 180.974 115.182 1.00 293.99 ? 818 GLY C CA  1 
ATOM   12089 C C   . GLY C 3 774 ? 231.160 179.984 114.046 1.00 293.99 ? 818 GLY C C   1 
ATOM   12090 O O   . GLY C 3 774 ? 230.666 180.218 112.939 1.00 293.99 ? 818 GLY C O   1 
ATOM   12091 N N   . VAL C 3 775 ? 231.839 178.870 114.310 1.00 300.66 ? 819 VAL C N   1 
ATOM   12092 C CA  . VAL C 3 775 ? 232.062 177.817 113.327 1.00 300.66 ? 819 VAL C CA  1 
ATOM   12093 C C   . VAL C 3 775 ? 231.269 176.590 113.753 1.00 300.66 ? 819 VAL C C   1 
ATOM   12094 O O   . VAL C 3 775 ? 231.365 176.151 114.905 1.00 300.66 ? 819 VAL C O   1 
ATOM   12095 C CB  . VAL C 3 775 ? 233.557 177.485 113.184 1.00 300.66 ? 819 VAL C CB  1 
ATOM   12096 C CG1 . VAL C 3 775 ? 233.799 176.651 111.935 1.00 300.66 ? 819 VAL C CG1 1 
ATOM   12097 C CG2 . VAL C 3 775 ? 234.384 178.762 113.148 1.00 300.66 ? 819 VAL C CG2 1 
ATOM   12098 N N   . GLY C 3 776 ? 230.489 176.040 112.826 1.00 326.50 ? 820 GLY C N   1 
ATOM   12099 C CA  . GLY C 3 776 ? 229.660 174.893 113.109 1.00 326.50 ? 820 GLY C CA  1 
ATOM   12100 C C   . GLY C 3 776 ? 230.438 173.593 113.105 1.00 326.50 ? 820 GLY C C   1 
ATOM   12101 O O   . GLY C 3 776 ? 231.671 173.578 113.049 1.00 326.50 ? 820 GLY C O   1 
ATOM   12102 N N   . PRO C 3 777 ? 229.727 172.474 113.166 1.00 365.84 ? 821 PRO C N   1 
ATOM   12103 C CA  . PRO C 3 777 ? 230.379 171.161 113.166 1.00 365.84 ? 821 PRO C CA  1 
ATOM   12104 C C   . PRO C 3 777 ? 230.854 170.789 111.764 1.00 365.84 ? 821 PRO C C   1 
ATOM   12105 O O   . PRO C 3 777 ? 230.727 171.554 110.810 1.00 365.84 ? 821 PRO C O   1 
ATOM   12106 C CB  . PRO C 3 777 ? 229.273 170.225 113.655 1.00 365.84 ? 821 PRO C CB  1 
ATOM   12107 C CG  . PRO C 3 777 ? 228.015 170.884 113.214 1.00 365.84 ? 821 PRO C CG  1 
ATOM   12108 C CD  . PRO C 3 777 ? 228.263 172.367 113.291 1.00 365.84 ? 821 PRO C CD  1 
ATOM   12109 N N   . GLU C 3 778 ? 231.407 169.583 111.655 1.00 415.50 ? 822 GLU C N   1 
ATOM   12110 C CA  . GLU C 3 778 ? 231.969 169.103 110.402 1.00 415.50 ? 822 GLU C CA  1 
ATOM   12111 C C   . GLU C 3 778 ? 231.520 167.671 110.150 1.00 415.50 ? 822 GLU C C   1 
ATOM   12112 O O   . GLU C 3 778 ? 231.249 166.912 111.085 1.00 415.50 ? 822 GLU C O   1 
ATOM   12113 C CB  . GLU C 3 778 ? 233.505 169.193 110.409 1.00 415.50 ? 822 GLU C CB  1 
ATOM   12114 C CG  . GLU C 3 778 ? 234.179 168.604 111.647 1.00 415.50 ? 822 GLU C CG  1 
ATOM   12115 C CD  . GLU C 3 778 ? 234.304 167.092 111.598 1.00 415.50 ? 822 GLU C CD  1 
ATOM   12116 O OE1 . GLU C 3 778 ? 234.259 166.524 110.487 1.00 415.50 ? 822 GLU C OE1 1 
ATOM   12117 O OE2 . GLU C 3 778 ? 234.445 166.472 112.673 1.00 415.50 ? 822 GLU C OE2 1 
ATOM   12118 N N   . LYS C 3 779 ? 231.442 167.313 108.871 1.00 402.08 ? 823 LYS C N   1 
ATOM   12119 C CA  . LYS C 3 779 ? 231.130 165.958 108.440 1.00 402.08 ? 823 LYS C CA  1 
ATOM   12120 C C   . LYS C 3 779 ? 232.322 165.389 107.685 1.00 402.08 ? 823 LYS C C   1 
ATOM   12121 O O   . LYS C 3 779 ? 233.023 166.117 106.975 1.00 402.08 ? 823 LYS C O   1 
ATOM   12122 C CB  . LYS C 3 779 ? 229.880 165.926 107.554 1.00 402.08 ? 823 LYS C CB  1 
ATOM   12123 C CG  . LYS C 3 779 ? 228.577 166.128 108.308 1.00 402.08 ? 823 LYS C CG  1 
ATOM   12124 C CD  . LYS C 3 779 ? 227.391 166.165 107.359 1.00 402.08 ? 823 LYS C CD  1 
ATOM   12125 C CE  . LYS C 3 779 ? 227.319 164.901 106.518 1.00 402.08 ? 823 LYS C CE  1 
ATOM   12126 N NZ  . LYS C 3 779 ? 227.217 163.678 107.360 1.00 402.08 ? 823 LYS C NZ  1 
ATOM   12127 N N   . SER C 3 780 ? 232.548 164.087 107.839 1.00 399.97 ? 824 SER C N   1 
ATOM   12128 C CA  . SER C 3 780 ? 233.705 163.427 107.255 1.00 399.97 ? 824 SER C CA  1 
ATOM   12129 C C   . SER C 3 780 ? 233.299 162.093 106.647 1.00 399.97 ? 824 SER C C   1 
ATOM   12130 O O   . SER C 3 780 ? 232.309 161.480 107.054 1.00 399.97 ? 824 SER C O   1 
ATOM   12131 C CB  . SER C 3 780 ? 234.807 163.208 108.299 1.00 399.97 ? 824 SER C CB  1 
ATOM   12132 O OG  . SER C 3 780 ? 234.443 162.193 109.218 1.00 399.97 ? 824 SER C OG  1 
ATOM   12133 N N   . MET C 3 781 ? 234.081 161.652 105.664 1.00 377.53 ? 825 MET C N   1 
ATOM   12134 C CA  . MET C 3 781 ? 233.867 160.367 105.015 1.00 377.53 ? 825 MET C CA  1 
ATOM   12135 C C   . MET C 3 781 ? 235.158 159.946 104.330 1.00 377.53 ? 825 MET C C   1 
ATOM   12136 O O   . MET C 3 781 ? 236.003 160.783 104.001 1.00 377.53 ? 825 MET C O   1 
ATOM   12137 C CB  . MET C 3 781 ? 232.705 160.425 104.014 1.00 377.53 ? 825 MET C CB  1 
ATOM   12138 C CG  . MET C 3 781 ? 232.689 161.655 103.115 1.00 377.53 ? 825 MET C CG  1 
ATOM   12139 S SD  . MET C 3 781 ? 233.900 161.629 101.778 1.00 377.53 ? 825 MET C SD  1 
ATOM   12140 C CE  . MET C 3 781 ? 233.397 160.152 100.901 1.00 377.53 ? 825 MET C CE  1 
ATOM   12141 N N   . TYR C 3 782 ? 235.304 158.640 104.127 1.00 357.68 ? 826 TYR C N   1 
ATOM   12142 C CA  . TYR C 3 782 ? 236.499 158.058 103.530 1.00 357.68 ? 826 TYR C CA  1 
ATOM   12143 C C   . TYR C 3 782 ? 236.144 157.459 102.176 1.00 357.68 ? 826 TYR C C   1 
ATOM   12144 O O   . TYR C 3 782 ? 235.207 156.660 102.074 1.00 357.68 ? 826 TYR C O   1 
ATOM   12145 C CB  . TYR C 3 782 ? 237.105 156.993 104.443 1.00 357.68 ? 826 TYR C CB  1 
ATOM   12146 C CG  . TYR C 3 782 ? 237.707 157.540 105.717 1.00 357.68 ? 826 TYR C CG  1 
ATOM   12147 C CD1 . TYR C 3 782 ? 239.027 157.970 105.755 1.00 357.68 ? 826 TYR C CD1 1 
ATOM   12148 C CD2 . TYR C 3 782 ? 236.958 157.623 106.883 1.00 357.68 ? 826 TYR C CD2 1 
ATOM   12149 C CE1 . TYR C 3 782 ? 239.583 158.469 106.918 1.00 357.68 ? 826 TYR C CE1 1 
ATOM   12150 C CE2 . TYR C 3 782 ? 237.505 158.120 108.051 1.00 357.68 ? 826 TYR C CE2 1 
ATOM   12151 C CZ  . TYR C 3 782 ? 238.818 158.541 108.063 1.00 357.68 ? 826 TYR C CZ  1 
ATOM   12152 O OH  . TYR C 3 782 ? 239.366 159.038 109.223 1.00 357.68 ? 826 TYR C OH  1 
ATOM   12153 N N   . VAL C 3 783 ? 236.890 157.847 101.144 1.00 299.52 ? 827 VAL C N   1 
ATOM   12154 C CA  . VAL C 3 783 ? 236.722 157.307 99.803  1.00 299.52 ? 827 VAL C CA  1 
ATOM   12155 C C   . VAL C 3 783 ? 238.102 157.074 99.202  1.00 299.52 ? 827 VAL C C   1 
ATOM   12156 O O   . VAL C 3 783 ? 239.083 157.723 99.579  1.00 299.52 ? 827 VAL C O   1 
ATOM   12157 C CB  . VAL C 3 783 ? 235.874 158.241 98.905  1.00 299.52 ? 827 VAL C CB  1 
ATOM   12158 C CG1 . VAL C 3 783 ? 236.697 159.428 98.423  1.00 299.52 ? 827 VAL C CG1 1 
ATOM   12159 C CG2 . VAL C 3 783 ? 235.280 157.471 97.732  1.00 299.52 ? 827 VAL C CG2 1 
ATOM   12160 N N   . VAL C 3 784 ? 238.177 156.123 98.276  1.00 277.66 ? 828 VAL C N   1 
ATOM   12161 C CA  . VAL C 3 784 ? 239.413 155.781 97.584  1.00 277.66 ? 828 VAL C CA  1 
ATOM   12162 C C   . VAL C 3 784 ? 239.296 156.244 96.140  1.00 277.66 ? 828 VAL C C   1 
ATOM   12163 O O   . VAL C 3 784 ? 238.302 155.948 95.465  1.00 277.66 ? 828 VAL C O   1 
ATOM   12164 C CB  . VAL C 3 784 ? 239.705 154.272 97.657  1.00 277.66 ? 828 VAL C CB  1 
ATOM   12165 C CG1 . VAL C 3 784 ? 241.115 153.981 97.167  1.00 277.66 ? 828 VAL C CG1 1 
ATOM   12166 C CG2 . VAL C 3 784 ? 239.512 153.764 99.078  1.00 277.66 ? 828 VAL C CG2 1 
ATOM   12167 N N   . THR C 3 785 ? 240.305 156.971 95.669  1.00 295.66 ? 829 THR C N   1 
ATOM   12168 C CA  . THR C 3 785 ? 240.296 157.463 94.302  1.00 295.66 ? 829 THR C CA  1 
ATOM   12169 C C   . THR C 3 785 ? 240.447 156.309 93.313  1.00 295.66 ? 829 THR C C   1 
ATOM   12170 O O   . THR C 3 785 ? 240.942 155.228 93.643  1.00 295.66 ? 829 THR C O   1 
ATOM   12171 C CB  . THR C 3 785 ? 241.412 158.487 94.090  1.00 295.66 ? 829 THR C CB  1 
ATOM   12172 O OG1 . THR C 3 785 ? 241.298 159.060 92.782  1.00 295.66 ? 829 THR C OG1 1 
ATOM   12173 C CG2 . THR C 3 785 ? 242.773 157.829 94.238  1.00 295.66 ? 829 THR C CG2 1 
ATOM   12174 N N   . LYS C 3 786 ? 240.004 156.554 92.083  1.00 312.82 ? 830 LYS C N   1 
ATOM   12175 C CA  . LYS C 3 786 ? 240.038 155.535 91.047  1.00 312.82 ? 830 LYS C CA  1 
ATOM   12176 C C   . LYS C 3 786 ? 241.455 155.366 90.505  1.00 312.82 ? 830 LYS C C   1 
ATOM   12177 O O   . LYS C 3 786 ? 242.383 156.098 90.859  1.00 312.82 ? 830 LYS C O   1 
ATOM   12178 C CB  . LYS C 3 786 ? 239.073 155.888 89.915  1.00 312.82 ? 830 LYS C CB  1 
ATOM   12179 C CG  . LYS C 3 786 ? 237.598 155.835 90.297  1.00 312.82 ? 830 LYS C CG  1 
ATOM   12180 C CD  . LYS C 3 786 ? 237.326 154.801 91.380  1.00 312.82 ? 830 LYS C CD  1 
ATOM   12181 C CE  . LYS C 3 786 ? 235.850 154.754 91.737  1.00 312.82 ? 830 LYS C CE  1 
ATOM   12182 N NZ  . LYS C 3 786 ? 235.637 154.438 93.176  1.00 312.82 ? 830 LYS C NZ  1 
ATOM   12183 N N   . GLU C 3 787 ? 241.613 154.380 89.628  1.00 328.16 ? 831 GLU C N   1 
ATOM   12184 C CA  . GLU C 3 787 ? 242.911 154.076 89.038  1.00 328.16 ? 831 GLU C CA  1 
ATOM   12185 C C   . GLU C 3 787 ? 242.901 154.378 87.544  1.00 328.16 ? 831 GLU C C   1 
ATOM   12186 O O   . GLU C 3 787 ? 241.950 154.965 87.026  1.00 328.16 ? 831 GLU C O   1 
ATOM   12187 C CB  . GLU C 3 787 ? 243.301 152.609 89.275  1.00 328.16 ? 831 GLU C CB  1 
ATOM   12188 C CG  . GLU C 3 787 ? 243.199 152.115 90.721  1.00 328.16 ? 831 GLU C CG  1 
ATOM   12189 C CD  . GLU C 3 787 ? 241.770 151.950 91.207  1.00 328.16 ? 831 GLU C CD  1 
ATOM   12190 O OE1 . GLU C 3 787 ? 240.888 151.660 90.371  1.00 328.16 ? 831 GLU C OE1 1 
ATOM   12191 O OE2 . GLU C 3 787 ? 241.529 152.112 92.422  1.00 328.16 ? 831 GLU C OE2 1 
HETATM 12192 C C1  . NAG D 4 .   ? 139.541 170.518 176.024 1.00 123.26 ? 1   NAG D C1  1 
HETATM 12193 C C2  . NAG D 4 .   ? 138.157 171.021 175.611 1.00 123.26 ? 1   NAG D C2  1 
HETATM 12194 C C3  . NAG D 4 .   ? 138.196 172.520 175.336 1.00 123.26 ? 1   NAG D C3  1 
HETATM 12195 C C4  . NAG D 4 .   ? 138.776 173.262 176.533 1.00 123.26 ? 1   NAG D C4  1 
HETATM 12196 C C5  . NAG D 4 .   ? 140.140 172.682 176.898 1.00 123.26 ? 1   NAG D C5  1 
HETATM 12197 C C6  . NAG D 4 .   ? 140.730 173.298 178.144 1.00 123.26 ? 1   NAG D C6  1 
HETATM 12198 C C7  . NAG D 4 .   ? 136.520 169.610 174.448 1.00 123.26 ? 1   NAG D C7  1 
HETATM 12199 C C8  . NAG D 4 .   ? 136.166 168.925 173.163 1.00 123.26 ? 1   NAG D C8  1 
HETATM 12200 N N2  . NAG D 4 .   ? 137.665 170.300 174.449 1.00 123.26 ? 1   NAG D N2  1 
HETATM 12201 O O3  . NAG D 4 .   ? 136.878 172.985 175.067 1.00 123.26 ? 1   NAG D O3  1 
HETATM 12202 O O4  . NAG D 4 .   ? 138.893 174.657 176.266 1.00 123.26 ? 1   NAG D O4  1 
HETATM 12203 O O5  . NAG D 4 .   ? 140.015 171.274 177.150 1.00 123.26 ? 1   NAG D O5  1 
HETATM 12204 O O6  . NAG D 4 .   ? 142.127 173.519 178.003 1.00 123.26 ? 1   NAG D O6  1 
HETATM 12205 O O7  . NAG D 4 .   ? 135.801 169.542 175.440 1.00 123.26 ? 1   NAG D O7  1 
HETATM 12206 C C1  . NAG D 4 .   ? 139.524 174.913 174.993 1.00 151.78 ? 2   NAG D C1  1 
HETATM 12207 C C2  . NAG D 4 .   ? 138.707 175.974 174.255 1.00 151.78 ? 2   NAG D C2  1 
HETATM 12208 C C3  . NAG D 4 .   ? 139.363 176.312 172.920 1.00 151.78 ? 2   NAG D C3  1 
HETATM 12209 C C4  . NAG D 4 .   ? 140.820 176.704 173.129 1.00 151.78 ? 2   NAG D C4  1 
HETATM 12210 C C5  . NAG D 4 .   ? 141.552 175.619 173.913 1.00 151.78 ? 2   NAG D C5  1 
HETATM 12211 C C6  . NAG D 4 .   ? 142.973 175.998 174.261 1.00 151.78 ? 2   NAG D C6  1 
HETATM 12212 C C7  . NAG D 4 .   ? 136.275 176.228 174.473 1.00 151.78 ? 2   NAG D C7  1 
HETATM 12213 C C8  . NAG D 4 .   ? 134.935 175.623 174.180 1.00 151.78 ? 2   NAG D C8  1 
HETATM 12214 N N2  . NAG D 4 .   ? 137.337 175.532 174.054 1.00 151.78 ? 2   NAG D N2  1 
HETATM 12215 O O3  . NAG D 4 .   ? 138.655 177.379 172.300 1.00 151.78 ? 2   NAG D O3  1 
HETATM 12216 O O4  . NAG D 4 .   ? 141.460 176.886 171.871 1.00 151.78 ? 2   NAG D O4  1 
HETATM 12217 O O5  . NAG D 4 .   ? 140.874 175.370 175.154 1.00 151.78 ? 2   NAG D O5  1 
HETATM 12218 O O6  . NAG D 4 .   ? 143.698 176.405 173.109 1.00 151.78 ? 2   NAG D O6  1 
HETATM 12219 O O7  . NAG D 4 .   ? 136.391 177.298 175.062 1.00 151.78 ? 2   NAG D O7  1 
HETATM 12220 C C1  . NAG E 4 .   ? 147.771 207.952 134.192 1.00 284.01 ? 1   NAG E C1  1 
HETATM 12221 C C2  . NAG E 4 .   ? 146.483 207.144 133.985 1.00 284.01 ? 1   NAG E C2  1 
HETATM 12222 C C3  . NAG E 4 .   ? 145.683 207.687 132.797 1.00 284.01 ? 1   NAG E C3  1 
HETATM 12223 C C4  . NAG E 4 .   ? 146.567 207.905 131.573 1.00 284.01 ? 1   NAG E C4  1 
HETATM 12224 C C5  . NAG E 4 .   ? 147.835 208.670 131.937 1.00 284.01 ? 1   NAG E C5  1 
HETATM 12225 C C6  . NAG E 4 .   ? 148.011 209.936 131.132 1.00 284.01 ? 1   NAG E C6  1 
HETATM 12226 C C7  . NAG E 4 .   ? 146.233 204.766 134.541 1.00 284.01 ? 1   NAG E C7  1 
HETATM 12227 C C8  . NAG E 4 .   ? 146.653 203.366 134.209 1.00 284.01 ? 1   NAG E C8  1 
HETATM 12228 N N2  . NAG E 4 .   ? 146.779 205.733 133.797 1.00 284.01 ? 1   NAG E N2  1 
HETATM 12229 O O3  . NAG E 4 .   ? 145.056 208.909 133.169 1.00 284.01 ? 1   NAG E O3  1 
HETATM 12230 O O4  . NAG E 4 .   ? 146.928 206.654 130.998 1.00 284.01 ? 1   NAG E O4  1 
HETATM 12231 O O5  . NAG E 4 .   ? 147.783 209.061 133.314 1.00 284.01 ? 1   NAG E O5  1 
HETATM 12232 O O6  . NAG E 4 .   ? 146.927 210.834 131.331 1.00 284.01 ? 1   NAG E O6  1 
HETATM 12233 O O7  . NAG E 4 .   ? 145.435 205.010 135.441 1.00 284.01 ? 1   NAG E O7  1 
HETATM 12234 C C1  . NAG E 4 .   ? 145.810 206.125 130.259 1.00 289.07 ? 2   NAG E C1  1 
HETATM 12235 C C2  . NAG E 4 .   ? 146.145 206.135 128.763 1.00 289.07 ? 2   NAG E C2  1 
HETATM 12236 C C3  . NAG E 4 .   ? 145.012 205.504 127.956 1.00 289.07 ? 2   NAG E C3  1 
HETATM 12237 C C4  . NAG E 4 .   ? 144.675 204.122 128.501 1.00 289.07 ? 2   NAG E C4  1 
HETATM 12238 C C5  . NAG E 4 .   ? 144.390 204.201 129.997 1.00 289.07 ? 2   NAG E C5  1 
HETATM 12239 C C6  . NAG E 4 .   ? 144.158 202.848 130.627 1.00 289.07 ? 2   NAG E C6  1 
HETATM 12240 C C7  . NAG E 4 .   ? 145.564 208.496 128.298 1.00 289.07 ? 2   NAG E C7  1 
HETATM 12241 C C8  . NAG E 4 .   ? 146.070 209.799 127.757 1.00 289.07 ? 2   NAG E C8  1 
HETATM 12242 N N2  . NAG E 4 .   ? 146.437 207.480 128.284 1.00 289.07 ? 2   NAG E N2  1 
HETATM 12243 O O3  . NAG E 4 .   ? 145.399 205.408 126.590 1.00 289.07 ? 2   NAG E O3  1 
HETATM 12244 O O4  . NAG E 4 .   ? 143.531 203.602 127.832 1.00 289.07 ? 2   NAG E O4  1 
HETATM 12245 O O5  . NAG E 4 .   ? 145.510 204.787 130.677 1.00 289.07 ? 2   NAG E O5  1 
HETATM 12246 O O6  . NAG E 4 .   ? 145.230 201.957 130.353 1.00 289.07 ? 2   NAG E O6  1 
HETATM 12247 O O7  . NAG E 4 .   ? 144.420 208.375 128.730 1.00 289.07 ? 2   NAG E O7  1 
HETATM 12248 C C1  . NAG F 4 .   ? 186.179 203.520 196.537 1.00 104.98 ? 1   NAG F C1  1 
HETATM 12249 C C2  . NAG F 4 .   ? 187.227 204.277 197.364 1.00 104.98 ? 1   NAG F C2  1 
HETATM 12250 C C3  . NAG F 4 .   ? 187.440 203.598 198.715 1.00 104.98 ? 1   NAG F C3  1 
HETATM 12251 C C4  . NAG F 4 .   ? 186.109 203.432 199.436 1.00 104.98 ? 1   NAG F C4  1 
HETATM 12252 C C5  . NAG F 4 .   ? 185.142 202.658 198.550 1.00 104.98 ? 1   NAG F C5  1 
HETATM 12253 C C6  . NAG F 4 .   ? 183.767 202.513 199.161 1.00 104.98 ? 1   NAG F C6  1 
HETATM 12254 C C7  . NAG F 4 .   ? 189.320 205.415 196.772 1.00 104.98 ? 1   NAG F C7  1 
HETATM 12255 C C8  . NAG F 4 .   ? 190.572 205.357 195.949 1.00 104.98 ? 1   NAG F C8  1 
HETATM 12256 N N2  . NAG F 4 .   ? 188.484 204.380 196.640 1.00 104.98 ? 1   NAG F N2  1 
HETATM 12257 O O3  . NAG F 4 .   ? 188.326 204.385 199.503 1.00 104.98 ? 1   NAG F O3  1 
HETATM 12258 O O4  . NAG F 4 .   ? 186.265 202.773 200.690 1.00 104.98 ? 1   NAG F O4  1 
HETATM 12259 O O5  . NAG F 4 .   ? 184.971 203.360 197.309 1.00 104.98 ? 1   NAG F O5  1 
HETATM 12260 O O6  . NAG F 4 .   ? 183.143 201.303 198.754 1.00 104.98 ? 1   NAG F O6  1 
HETATM 12261 O O7  . NAG F 4 .   ? 189.078 206.356 197.521 1.00 104.98 ? 1   NAG F O7  1 
HETATM 12262 C C1  . NAG F 4 .   ? 187.124 201.618 200.609 1.00 130.42 ? 2   NAG F C1  1 
HETATM 12263 C C2  . NAG F 4 .   ? 188.019 201.615 201.848 1.00 130.42 ? 2   NAG F C2  1 
HETATM 12264 C C3  . NAG F 4 .   ? 188.921 200.385 201.845 1.00 130.42 ? 2   NAG F C3  1 
HETATM 12265 C C4  . NAG F 4 .   ? 188.091 199.117 201.691 1.00 130.42 ? 2   NAG F C4  1 
HETATM 12266 C C5  . NAG F 4 .   ? 187.192 199.223 200.462 1.00 130.42 ? 2   NAG F C5  1 
HETATM 12267 C C6  . NAG F 4 .   ? 186.253 198.049 200.314 1.00 130.42 ? 2   NAG F C6  1 
HETATM 12268 C C7  . NAG F 4 .   ? 188.486 203.868 202.702 1.00 130.42 ? 2   NAG F C7  1 
HETATM 12269 C C8  . NAG F 4 .   ? 189.417 205.042 202.656 1.00 130.42 ? 2   NAG F C8  1 
HETATM 12270 N N2  . NAG F 4 .   ? 188.812 202.831 201.923 1.00 130.42 ? 2   NAG F N2  1 
HETATM 12271 O O3  . NAG F 4 .   ? 189.661 200.337 203.059 1.00 130.42 ? 2   NAG F O3  1 
HETATM 12272 O O4  . NAG F 4 .   ? 188.946 197.989 201.552 1.00 130.42 ? 2   NAG F O4  1 
HETATM 12273 O O5  . NAG F 4 .   ? 186.374 200.399 200.554 1.00 130.42 ? 2   NAG F O5  1 
HETATM 12274 O O6  . NAG F 4 .   ? 186.829 197.023 199.517 1.00 130.42 ? 2   NAG F O6  1 
HETATM 12275 O O7  . NAG F 4 .   ? 187.484 203.859 203.411 1.00 130.42 ? 2   NAG F O7  1 
HETATM 12276 C C1  . NAG G 4 .   ? 190.147 211.096 182.737 1.00 76.29  ? 1   NAG G C1  1 
HETATM 12277 C C2  . NAG G 4 .   ? 191.396 211.773 183.304 1.00 76.29  ? 1   NAG G C2  1 
HETATM 12278 C C3  . NAG G 4 .   ? 191.384 213.265 182.983 1.00 76.29  ? 1   NAG G C3  1 
HETATM 12279 C C4  . NAG G 4 .   ? 191.197 213.488 181.489 1.00 76.29  ? 1   NAG G C4  1 
HETATM 12280 C C5  . NAG G 4 .   ? 189.954 212.751 181.001 1.00 76.29  ? 1   NAG G C5  1 
HETATM 12281 C C6  . NAG G 4 .   ? 189.764 212.832 179.504 1.00 76.29  ? 1   NAG G C6  1 
HETATM 12282 C C7  . NAG G 4 .   ? 192.249 210.599 185.285 1.00 76.29  ? 1   NAG G C7  1 
HETATM 12283 C C8  . NAG G 4 .   ? 192.235 210.525 186.782 1.00 76.29  ? 1   NAG G C8  1 
HETATM 12284 N N2  . NAG G 4 .   ? 191.497 211.560 184.739 1.00 76.29  ? 1   NAG G N2  1 
HETATM 12285 O O3  . NAG G 4 .   ? 192.607 213.852 183.414 1.00 76.29  ? 1   NAG G O3  1 
HETATM 12286 O O4  . NAG G 4 .   ? 191.056 214.878 181.218 1.00 76.29  ? 1   NAG G O4  1 
HETATM 12287 O O5  . NAG G 4 .   ? 190.054 211.358 181.330 1.00 76.29  ? 1   NAG G O5  1 
HETATM 12288 O O6  . NAG G 4 .   ? 190.775 212.112 178.813 1.00 76.29  ? 1   NAG G O6  1 
HETATM 12289 O O7  . NAG G 4 .   ? 192.910 209.824 184.601 1.00 76.29  ? 1   NAG G O7  1 
HETATM 12290 C C1  . NAG G 4 .   ? 192.201 215.326 180.466 1.00 93.37  ? 2   NAG G C1  1 
HETATM 12291 C C2  . NAG G 4 .   ? 191.756 216.448 179.527 1.00 93.37  ? 2   NAG G C2  1 
HETATM 12292 C C3  . NAG G 4 .   ? 192.951 216.987 178.746 1.00 93.37  ? 2   NAG G C3  1 
HETATM 12293 C C4  . NAG G 4 .   ? 194.066 217.399 179.698 1.00 93.37  ? 2   NAG G C4  1 
HETATM 12294 C C5  . NAG G 4 .   ? 194.416 216.243 180.633 1.00 93.37  ? 2   NAG G C5  1 
HETATM 12295 C C6  . NAG G 4 .   ? 195.433 216.621 181.685 1.00 93.37  ? 2   NAG G C6  1 
HETATM 12296 C C7  . NAG G 4 .   ? 189.530 216.589 178.494 1.00 93.37  ? 2   NAG G C7  1 
HETATM 12297 C C8  . NAG G 4 .   ? 189.308 217.794 179.358 1.00 93.37  ? 2   NAG G C8  1 
HETATM 12298 N N2  . NAG G 4 .   ? 190.718 215.987 178.618 1.00 93.37  ? 2   NAG G N2  1 
HETATM 12299 O O3  . NAG G 4 .   ? 192.542 218.104 177.965 1.00 93.37  ? 2   NAG G O3  1 
HETATM 12300 O O4  . NAG G 4 .   ? 195.224 217.772 178.960 1.00 93.37  ? 2   NAG G O4  1 
HETATM 12301 O O5  . NAG G 4 .   ? 193.241 215.806 181.331 1.00 93.37  ? 2   NAG G O5  1 
HETATM 12302 O O6  . NAG G 4 .   ? 196.675 215.968 181.464 1.00 93.37  ? 2   NAG G O6  1 
HETATM 12303 O O7  . NAG G 4 .   ? 188.672 216.178 177.719 1.00 93.37  ? 2   NAG G O7  1 
HETATM 12304 C C1  . NAG H 4 .   ? 164.703 166.812 232.571 1.00 42.20  ? 1   NAG H C1  1 
HETATM 12305 C C2  . NAG H 4 .   ? 164.670 166.122 233.939 1.00 42.20  ? 1   NAG H C2  1 
HETATM 12306 C C3  . NAG H 4 .   ? 163.228 165.899 234.391 1.00 42.20  ? 1   NAG H C3  1 
HETATM 12307 C C4  . NAG H 4 .   ? 162.455 167.210 234.355 1.00 42.20  ? 1   NAG H C4  1 
HETATM 12308 C C5  . NAG H 4 .   ? 162.559 167.839 232.969 1.00 42.20  ? 1   NAG H C5  1 
HETATM 12309 C C6  . NAG H 4 .   ? 161.899 169.195 232.880 1.00 42.20  ? 1   NAG H C6  1 
HETATM 12310 C C7  . NAG H 4 .   ? 165.118 163.821 233.144 1.00 42.20  ? 1   NAG H C7  1 
HETATM 12311 C C8  . NAG H 4 .   ? 166.011 162.627 233.291 1.00 42.20  ? 1   NAG H C8  1 
HETATM 12312 N N2  . NAG H 4 .   ? 165.411 164.869 233.927 1.00 42.20  ? 1   NAG H N2  1 
HETATM 12313 O O3  . NAG H 4 .   ? 163.222 165.364 235.710 1.00 42.20  ? 1   NAG H O3  1 
HETATM 12314 O O4  . NAG H 4 .   ? 161.087 166.981 234.673 1.00 42.20  ? 1   NAG H O4  1 
HETATM 12315 O O5  . NAG H 4 .   ? 163.939 168.028 232.624 1.00 42.20  ? 1   NAG H O5  1 
HETATM 12316 O O6  . NAG H 4 .   ? 162.380 169.935 231.766 1.00 42.20  ? 1   NAG H O6  1 
HETATM 12317 O O7  . NAG H 4 .   ? 164.177 163.833 232.355 1.00 42.20  ? 1   NAG H O7  1 
HETATM 12318 C C1  . NAG H 4 .   ? 160.801 167.590 235.949 1.00 47.46  ? 2   NAG H C1  1 
HETATM 12319 C C2  . NAG H 4 .   ? 159.360 168.097 235.936 1.00 47.46  ? 2   NAG H C2  1 
HETATM 12320 C C3  . NAG H 4 .   ? 159.003 168.705 237.289 1.00 47.46  ? 2   NAG H C3  1 
HETATM 12321 C C4  . NAG H 4 .   ? 159.288 167.713 238.410 1.00 47.46  ? 2   NAG H C4  1 
HETATM 12322 C C5  . NAG H 4 .   ? 160.728 167.216 238.323 1.00 47.46  ? 2   NAG H C5  1 
HETATM 12323 C C6  . NAG H 4 .   ? 161.042 166.135 239.330 1.00 47.46  ? 2   NAG H C6  1 
HETATM 12324 C C7  . NAG H 4 .   ? 158.248 168.910 233.900 1.00 47.46  ? 2   NAG H C7  1 
HETATM 12325 C C8  . NAG H 4 .   ? 157.426 167.656 233.960 1.00 47.46  ? 2   NAG H C8  1 
HETATM 12326 N N2  . NAG H 4 .   ? 159.155 169.065 234.871 1.00 47.46  ? 2   NAG H N2  1 
HETATM 12327 O O3  . NAG H 4 .   ? 157.627 169.068 237.298 1.00 47.46  ? 2   NAG H O3  1 
HETATM 12328 O O4  . NAG H 4 .   ? 159.082 168.334 239.673 1.00 47.46  ? 2   NAG H O4  1 
HETATM 12329 O O5  . NAG H 4 .   ? 160.975 166.655 237.024 1.00 47.46  ? 2   NAG H O5  1 
HETATM 12330 O O6  . NAG H 4 .   ? 160.621 164.858 238.871 1.00 47.46  ? 2   NAG H O6  1 
HETATM 12331 O O7  . NAG H 4 .   ? 158.097 169.744 233.013 1.00 47.46  ? 2   NAG H O7  1 
HETATM 12332 C C1  . NAG I 5 .   ? 158.629 171.681 141.011 1.00 259.05 ? 701 NAG B C1  1 
HETATM 12333 C C2  . NAG I 5 .   ? 158.355 171.645 139.507 1.00 259.05 ? 701 NAG B C2  1 
HETATM 12334 C C3  . NAG I 5 .   ? 159.576 171.125 138.743 1.00 259.05 ? 701 NAG B C3  1 
HETATM 12335 C C4  . NAG I 5 .   ? 160.196 169.911 139.428 1.00 259.05 ? 701 NAG B C4  1 
HETATM 12336 C C5  . NAG I 5 .   ? 160.444 170.177 140.910 1.00 259.05 ? 701 NAG B C5  1 
HETATM 12337 C C6  . NAG I 5 .   ? 161.903 170.087 141.291 1.00 259.05 ? 701 NAG B C6  1 
HETATM 12338 C C7  . NAG I 5 .   ? 155.949 171.343 139.117 1.00 259.05 ? 701 NAG B C7  1 
HETATM 12339 C C8  . NAG I 5 .   ? 154.859 170.363 138.803 1.00 259.05 ? 701 NAG B C8  1 
HETATM 12340 N N2  . NAG I 5 .   ? 157.183 170.837 139.209 1.00 259.05 ? 701 NAG B N2  1 
HETATM 12341 O O3  . NAG I 5 .   ? 160.542 172.165 138.633 1.00 259.05 ? 701 NAG B O3  1 
HETATM 12342 O O4  . NAG I 5 .   ? 159.336 168.785 139.292 1.00 259.05 ? 701 NAG B O4  1 
HETATM 12343 O O5  . NAG I 5 .   ? 160.010 171.501 141.245 1.00 259.05 ? 701 NAG B O5  1 
HETATM 12344 O O6  . NAG I 5 .   ? 162.159 168.951 142.105 1.00 259.05 ? 701 NAG B O6  1 
HETATM 12345 O O7  . NAG I 5 .   ? 155.722 172.538 139.281 1.00 259.05 ? 701 NAG B O7  1 
HETATM 12346 C C1  . NAG J 5 .   ? 218.580 107.439 132.835 1.00 345.47 ? 702 NAG B C1  1 
HETATM 12347 C C2  . NAG J 5 .   ? 219.530 106.339 132.362 1.00 345.47 ? 702 NAG B C2  1 
HETATM 12348 C C3  . NAG J 5 .   ? 220.461 106.860 131.263 1.00 345.47 ? 702 NAG B C3  1 
HETATM 12349 C C4  . NAG J 5 .   ? 220.985 108.257 131.583 1.00 345.47 ? 702 NAG B C4  1 
HETATM 12350 C C5  . NAG J 5 .   ? 219.847 109.213 131.930 1.00 345.47 ? 702 NAG B C5  1 
HETATM 12351 C C6  . NAG J 5 .   ? 219.717 110.357 130.951 1.00 345.47 ? 702 NAG B C6  1 
HETATM 12352 C C7  . NAG J 5 .   ? 219.838 104.854 134.292 1.00 345.47 ? 702 NAG B C7  1 
HETATM 12353 C C8  . NAG J 5 .   ? 220.768 104.420 135.385 1.00 345.47 ? 702 NAG B C8  1 
HETATM 12354 N N2  . NAG J 5 .   ? 220.301 105.804 133.473 1.00 345.47 ? 702 NAG B N2  1 
HETATM 12355 O O3  . NAG J 5 .   ? 219.764 106.875 130.022 1.00 345.47 ? 702 NAG B O3  1 
HETATM 12356 O O4  . NAG J 5 .   ? 221.891 108.195 132.678 1.00 345.47 ? 702 NAG B O4  1 
HETATM 12357 O O5  . NAG J 5 .   ? 218.598 108.511 131.913 1.00 345.47 ? 702 NAG B O5  1 
HETATM 12358 O O6  . NAG J 5 .   ? 220.230 110.009 129.673 1.00 345.47 ? 702 NAG B O6  1 
HETATM 12359 O O7  . NAG J 5 .   ? 218.721 104.367 134.157 1.00 345.47 ? 702 NAG B O7  1 
HETATM 12360 C C1  . NAG K 5 .   ? 180.408 150.293 162.868 1.00 175.92 ? 703 NAG B C1  1 
HETATM 12361 C C2  . NAG K 5 .   ? 180.238 150.979 164.230 1.00 175.92 ? 703 NAG B C2  1 
HETATM 12362 C C3  . NAG K 5 .   ? 181.590 151.440 164.783 1.00 175.92 ? 703 NAG B C3  1 
HETATM 12363 C C4  . NAG K 5 .   ? 182.335 152.316 163.782 1.00 175.92 ? 703 NAG B C4  1 
HETATM 12364 C C5  . NAG K 5 .   ? 182.213 151.749 162.373 1.00 175.92 ? 703 NAG B C5  1 
HETATM 12365 C C6  . NAG K 5 .   ? 183.528 151.728 161.628 1.00 175.92 ? 703 NAG B C6  1 
HETATM 12366 C C7  . NAG K 5 .   ? 178.618 152.563 165.177 1.00 175.92 ? 703 NAG B C7  1 
HETATM 12367 C C8  . NAG K 5 .   ? 177.717 153.728 164.898 1.00 175.92 ? 703 NAG B C8  1 
HETATM 12368 N N2  . NAG K 5 .   ? 179.317 152.101 164.135 1.00 175.92 ? 703 NAG B N2  1 
HETATM 12369 O O3  . NAG K 5 .   ? 182.378 150.301 165.112 1.00 175.92 ? 703 NAG B O3  1 
HETATM 12370 O O4  . NAG K 5 .   ? 181.805 153.636 163.802 1.00 175.92 ? 703 NAG B O4  1 
HETATM 12371 O O5  . NAG K 5 .   ? 181.760 150.392 162.448 1.00 175.92 ? 703 NAG B O5  1 
HETATM 12372 O O6  . NAG K 5 .   ? 184.164 150.462 161.734 1.00 175.92 ? 703 NAG B O6  1 
HETATM 12373 O O7  . NAG K 5 .   ? 178.709 152.064 166.294 1.00 175.92 ? 703 NAG B O7  1 
HETATM 12374 C C1  . NAG L 5 .   ? 205.086 123.659 145.128 1.00 238.32 ? 704 NAG B C1  1 
HETATM 12375 C C2  . NAG L 5 .   ? 204.676 124.818 144.219 1.00 238.32 ? 704 NAG B C2  1 
HETATM 12376 C C3  . NAG L 5 .   ? 203.277 125.324 144.582 1.00 238.32 ? 704 NAG B C3  1 
HETATM 12377 C C4  . NAG L 5 .   ? 203.090 125.433 146.092 1.00 238.32 ? 704 NAG B C4  1 
HETATM 12378 C C5  . NAG L 5 .   ? 203.489 124.139 146.796 1.00 238.32 ? 704 NAG B C5  1 
HETATM 12379 C C6  . NAG L 5 .   ? 202.341 123.488 147.533 1.00 238.32 ? 704 NAG B C6  1 
HETATM 12380 C C7  . NAG L 5 .   ? 205.977 126.649 143.229 1.00 238.32 ? 704 NAG B C7  1 
HETATM 12381 C C8  . NAG L 5 .   ? 206.994 127.722 143.478 1.00 238.32 ? 704 NAG B C8  1 
HETATM 12382 N N2  . NAG L 5 .   ? 205.645 125.900 144.285 1.00 238.32 ? 704 NAG B N2  1 
HETATM 12383 O O3  . NAG L 5 .   ? 202.301 124.445 144.035 1.00 238.32 ? 704 NAG B O3  1 
HETATM 12384 O O4  . NAG L 5 .   ? 203.876 126.504 146.602 1.00 238.32 ? 704 NAG B O4  1 
HETATM 12385 O O5  . NAG L 5 .   ? 203.956 123.186 145.834 1.00 238.32 ? 704 NAG B O5  1 
HETATM 12386 O O6  . NAG L 5 .   ? 202.721 123.099 148.846 1.00 238.32 ? 704 NAG B O6  1 
HETATM 12387 O O7  . NAG L 5 .   ? 205.480 126.467 142.122 1.00 238.32 ? 704 NAG B O7  1 
HETATM 12388 C C1  . NAG M 5 .   ? 201.367 105.471 143.517 1.00 201.58 ? 705 NAG B C1  1 
HETATM 12389 C C2  . NAG M 5 .   ? 200.310 104.965 144.497 1.00 201.58 ? 705 NAG B C2  1 
HETATM 12390 C C3  . NAG M 5 .   ? 200.581 105.514 145.895 1.00 201.58 ? 705 NAG B C3  1 
HETATM 12391 C C4  . NAG M 5 .   ? 202.008 105.199 146.323 1.00 201.58 ? 705 NAG B C4  1 
HETATM 12392 C C5  . NAG M 5 .   ? 202.998 105.686 145.267 1.00 201.58 ? 705 NAG B C5  1 
HETATM 12393 C C6  . NAG M 5 .   ? 204.426 105.296 145.570 1.00 201.58 ? 705 NAG B C6  1 
HETATM 12394 C C7  . NAG M 5 .   ? 198.023 104.423 143.791 1.00 201.58 ? 705 NAG B C7  1 
HETATM 12395 C C8  . NAG M 5 .   ? 196.700 104.972 143.347 1.00 201.58 ? 705 NAG B C8  1 
HETATM 12396 N N2  . NAG M 5 .   ? 198.973 105.326 144.056 1.00 201.58 ? 705 NAG B N2  1 
HETATM 12397 O O3  . NAG M 5 .   ? 199.659 104.942 146.816 1.00 201.58 ? 705 NAG B O3  1 
HETATM 12398 O O4  . NAG M 5 .   ? 202.296 105.832 147.564 1.00 201.58 ? 705 NAG B O4  1 
HETATM 12399 O O5  . NAG M 5 .   ? 202.673 105.114 143.991 1.00 201.58 ? 705 NAG B O5  1 
HETATM 12400 O O6  . NAG M 5 .   ? 205.188 106.413 146.007 1.00 201.58 ? 705 NAG B O6  1 
HETATM 12401 O O7  . NAG M 5 .   ? 198.223 103.218 143.904 1.00 201.58 ? 705 NAG B O7  1 
HETATM 12402 C C1  . NAG N 5 .   ? 147.574 225.423 146.038 1.00 269.56 ? 706 NAG B C1  1 
HETATM 12403 C C2  . NAG N 5 .   ? 147.043 225.746 147.432 1.00 269.56 ? 706 NAG B C2  1 
HETATM 12404 C C3  . NAG N 5 .   ? 147.397 224.630 148.420 1.00 269.56 ? 706 NAG B C3  1 
HETATM 12405 C C4  . NAG N 5 .   ? 148.770 224.031 148.132 1.00 269.56 ? 706 NAG B C4  1 
HETATM 12406 C C5  . NAG N 5 .   ? 148.897 223.579 146.678 1.00 269.56 ? 706 NAG B C5  1 
HETATM 12407 C C6  . NAG N 5 .   ? 148.949 222.076 146.528 1.00 269.56 ? 706 NAG B C6  1 
HETATM 12408 C C7  . NAG N 5 .   ? 146.976 228.194 147.598 1.00 269.56 ? 706 NAG B C7  1 
HETATM 12409 C C8  . NAG N 5 .   ? 147.630 229.416 148.169 1.00 269.56 ? 706 NAG B C8  1 
HETATM 12410 N N2  . NAG N 5 .   ? 147.550 227.025 147.902 1.00 269.56 ? 706 NAG B N2  1 
HETATM 12411 O O3  . NAG N 5 .   ? 146.402 223.613 148.359 1.00 269.56 ? 706 NAG B O3  1 
HETATM 12412 O O4  . NAG N 5 .   ? 149.787 224.986 148.416 1.00 269.56 ? 706 NAG B O4  1 
HETATM 12413 O O5  . NAG N 5 .   ? 147.769 224.031 145.918 1.00 269.56 ? 706 NAG B O5  1 
HETATM 12414 O O6  . NAG N 5 .   ? 149.844 221.492 147.465 1.00 269.56 ? 706 NAG B O6  1 
HETATM 12415 O O7  . NAG N 5 .   ? 145.973 228.262 146.893 1.00 269.56 ? 706 NAG B O7  1 
HETATM 12416 C C1  . NAG O 5 .   ? 189.046 163.542 202.064 1.00 75.12  ? 901 NAG C C1  1 
HETATM 12417 C C2  . NAG O 5 .   ? 189.949 163.128 203.231 1.00 75.12  ? 901 NAG C C2  1 
HETATM 12418 C C3  . NAG O 5 .   ? 190.462 161.707 203.022 1.00 75.12  ? 901 NAG C C3  1 
HETATM 12419 C C4  . NAG O 5 .   ? 189.300 160.751 202.783 1.00 75.12  ? 901 NAG C C4  1 
HETATM 12420 C C5  . NAG O 5 .   ? 188.427 161.255 201.637 1.00 75.12  ? 901 NAG C C5  1 
HETATM 12421 C C6  . NAG O 5 .   ? 187.192 160.413 201.420 1.00 75.12  ? 901 NAG C C6  1 
HETATM 12422 C C7  . NAG O 5 .   ? 191.250 164.788 204.487 1.00 75.12  ? 901 NAG C C7  1 
HETATM 12423 C C8  . NAG O 5 .   ? 192.447 165.691 204.475 1.00 75.12  ? 901 NAG C C8  1 
HETATM 12424 N N2  . NAG O 5 .   ? 191.059 164.055 203.386 1.00 75.12  ? 901 NAG C N2  1 
HETATM 12425 O O3  . NAG O 5 .   ? 191.202 161.297 204.166 1.00 75.12  ? 901 NAG C O3  1 
HETATM 12426 O O4  . NAG O 5 .   ? 189.794 159.456 202.462 1.00 75.12  ? 901 NAG C O4  1 
HETATM 12427 O O5  . NAG O 5 .   ? 187.975 162.588 201.917 1.00 75.12  ? 901 NAG C O5  1 
HETATM 12428 O O6  . NAG O 5 .   ? 186.396 160.922 200.358 1.00 75.12  ? 901 NAG C O6  1 
HETATM 12429 O O7  . NAG O 5 .   ? 190.492 164.725 205.450 1.00 75.12  ? 901 NAG C O7  1 
HETATM 12430 C C1  . NAG P 5 .   ? 170.302 213.252 166.692 1.00 70.17  ? 902 NAG C C1  1 
HETATM 12431 C C2  . NAG P 5 .   ? 169.176 213.716 165.771 1.00 70.17  ? 902 NAG C C2  1 
HETATM 12432 C C3  . NAG P 5 .   ? 168.754 215.138 166.130 1.00 70.17  ? 902 NAG C C3  1 
HETATM 12433 C C4  . NAG P 5 .   ? 168.411 215.234 167.611 1.00 70.17  ? 902 NAG C C4  1 
HETATM 12434 C C5  . NAG P 5 .   ? 169.563 214.698 168.458 1.00 70.17  ? 902 NAG C C5  1 
HETATM 12435 C C6  . NAG P 5 .   ? 169.239 214.648 169.933 1.00 70.17  ? 902 NAG C C6  1 
HETATM 12436 C C7  . NAG P 5 .   ? 169.199 212.649 163.560 1.00 70.17  ? 902 NAG C C7  1 
HETATM 12437 C C8  . NAG P 5 .   ? 169.707 212.728 162.152 1.00 70.17  ? 902 NAG C C8  1 
HETATM 12438 N N2  . NAG P 5 .   ? 169.577 213.639 164.376 1.00 70.17  ? 902 NAG C N2  1 
HETATM 12439 O O3  . NAG P 5 .   ? 167.627 215.511 165.345 1.00 70.17  ? 902 NAG C O3  1 
HETATM 12440 O O4  . NAG P 5 .   ? 168.162 216.589 167.966 1.00 70.17  ? 902 NAG C O4  1 
HETATM 12441 O O5  . NAG P 5 .   ? 169.881 213.357 168.058 1.00 70.17  ? 902 NAG C O5  1 
HETATM 12442 O O6  . NAG P 5 .   ? 170.230 215.313 170.705 1.00 70.17  ? 902 NAG C O6  1 
HETATM 12443 O O7  . NAG P 5 .   ? 168.480 211.731 163.942 1.00 70.17  ? 902 NAG C O7  1 
HETATM 12444 C C1  . NAG Q 5 .   ? 188.326 219.194 141.987 1.00 89.13  ? 903 NAG C C1  1 
HETATM 12445 C C2  . NAG Q 5 .   ? 189.267 220.285 141.482 1.00 89.13  ? 903 NAG C C2  1 
HETATM 12446 C C3  . NAG Q 5 .   ? 190.436 220.461 142.446 1.00 89.13  ? 903 NAG C C3  1 
HETATM 12447 C C4  . NAG Q 5 .   ? 189.927 220.704 143.861 1.00 89.13  ? 903 NAG C C4  1 
HETATM 12448 C C5  . NAG Q 5 .   ? 188.955 219.601 144.269 1.00 89.13  ? 903 NAG C C5  1 
HETATM 12449 C C6  . NAG Q 5 .   ? 188.316 219.843 145.616 1.00 89.13  ? 903 NAG C C6  1 
HETATM 12450 C C7  . NAG Q 5 .   ? 189.279 220.581 139.046 1.00 89.13  ? 903 NAG C C7  1 
HETATM 12451 C C8  . NAG Q 5 .   ? 189.889 220.146 137.747 1.00 89.13  ? 903 NAG C C8  1 
HETATM 12452 N N2  . NAG Q 5 .   ? 189.748 219.982 140.144 1.00 89.13  ? 903 NAG C N2  1 
HETATM 12453 O O3  . NAG Q 5 .   ? 191.240 221.557 142.023 1.00 89.13  ? 903 NAG C O3  1 
HETATM 12454 O O4  . NAG Q 5 .   ? 191.018 220.730 144.774 1.00 89.13  ? 903 NAG C O4  1 
HETATM 12455 O O5  . NAG Q 5 .   ? 187.887 219.512 143.314 1.00 89.13  ? 903 NAG C O5  1 
HETATM 12456 O O6  . NAG Q 5 .   ? 188.801 218.930 146.592 1.00 89.13  ? 903 NAG C O6  1 
HETATM 12457 O O7  . NAG Q 5 .   ? 188.401 221.437 139.097 1.00 89.13  ? 903 NAG C O7  1 
# 
