data_8UYT
# 
_entry.id   8UYT 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.399 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8UYT         pdb_00008uyt 10.2210/pdb8uyt/pdb 
WWPDB D_1000276208 ?            ?                   
EMDB  EMD-42822    ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2024-11-20 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8UYT 
_pdbx_database_status.recvd_initial_deposition_date   2023-11-14 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
loop_
_pdbx_database_related.db_name 
_pdbx_database_related.details 
_pdbx_database_related.db_id 
_pdbx_database_related.content_type 
EMDB . EMD-42822 'associated EM volume' 
EMDB . EMD-42823 'other EM volume'      
EMDB . EMD-42824 'other EM volume'      
EMDB . EMD-42825 'other EM volume'      
EMDB . EMD-42826 'other EM volume'      
EMDB . EMD-42827 'other EM volume'      
EMDB . EMD-42828 'other EM volume'      
# 
_pdbx_contact_author.id                 3 
_pdbx_contact_author.email              joewang@psu.edu 
_pdbx_contact_author.name_first         'Joseph CY' 
_pdbx_contact_author.name_last          Wang 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0001-6580-3531 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Bianchini, E.N.' 1 0000-0003-2787-6240 
'Wang, J.C.Y.'    2 0000-0001-6580-3531 
'Hu, J.'          3 0000-0002-3967-2133 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
'Structural Insights into Capsid Conformation and Dynamics: Cryo-EM Structures of HBV Capsids from HEK-293T Cells' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Bianchini, E.N.' 1 0000-0003-2787-6240 
primary 'Liu, H.'         2 0000-0002-6263-1508 
primary 'Cai, Y.'         3 ?                   
primary 'Shanklin, J.'    4 0000-0002-6774-8043 
primary 'Hu, J.'          5 ?                   
primary 'Wang, J.C.Y.'    6 0000-0001-6580-3531 
# 
_entity.id                         1 
_entity.type                       polymer 
_entity.src_method                 man 
_entity.pdbx_description           'Capsid protein' 
_entity.formula_weight             17386.936 
_entity.pdbx_number_of_molecules   4 
_entity.pdbx_ec                    ? 
_entity.pdbx_mutation              ? 
_entity.pdbx_fragment              ? 
_entity.details                    ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MDIDPYKEFGATVELLSFLPSDFFPSVRDLLDTASALYREALESPEHCSPHHTALRQAILCWGELMTLATWVGVNLEDPA
SRDLVVSYVNTNMGLKFRQLLWFHISCLTFGRETVIEYLVSFGVWIRTPPAYRPPNAPILSTLPETTVVRRRG
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MDIDPYKEFGATVELLSFLPSDFFPSVRDLLDTASALYREALESPEHCSPHHTALRQAILCWGELMTLATWVGVNLEDPA
SRDLVVSYVNTNMGLKFRQLLWFHISCLTFGRETVIEYLVSFGVWIRTPPAYRPPNAPILSTLPETTVVRRRG
;
_entity_poly.pdbx_strand_id                 A,B,C,D 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   ASP n 
1 3   ILE n 
1 4   ASP n 
1 5   PRO n 
1 6   TYR n 
1 7   LYS n 
1 8   GLU n 
1 9   PHE n 
1 10  GLY n 
1 11  ALA n 
1 12  THR n 
1 13  VAL n 
1 14  GLU n 
1 15  LEU n 
1 16  LEU n 
1 17  SER n 
1 18  PHE n 
1 19  LEU n 
1 20  PRO n 
1 21  SER n 
1 22  ASP n 
1 23  PHE n 
1 24  PHE n 
1 25  PRO n 
1 26  SER n 
1 27  VAL n 
1 28  ARG n 
1 29  ASP n 
1 30  LEU n 
1 31  LEU n 
1 32  ASP n 
1 33  THR n 
1 34  ALA n 
1 35  SER n 
1 36  ALA n 
1 37  LEU n 
1 38  TYR n 
1 39  ARG n 
1 40  GLU n 
1 41  ALA n 
1 42  LEU n 
1 43  GLU n 
1 44  SER n 
1 45  PRO n 
1 46  GLU n 
1 47  HIS n 
1 48  CYS n 
1 49  SER n 
1 50  PRO n 
1 51  HIS n 
1 52  HIS n 
1 53  THR n 
1 54  ALA n 
1 55  LEU n 
1 56  ARG n 
1 57  GLN n 
1 58  ALA n 
1 59  ILE n 
1 60  LEU n 
1 61  CYS n 
1 62  TRP n 
1 63  GLY n 
1 64  GLU n 
1 65  LEU n 
1 66  MET n 
1 67  THR n 
1 68  LEU n 
1 69  ALA n 
1 70  THR n 
1 71  TRP n 
1 72  VAL n 
1 73  GLY n 
1 74  VAL n 
1 75  ASN n 
1 76  LEU n 
1 77  GLU n 
1 78  ASP n 
1 79  PRO n 
1 80  ALA n 
1 81  SER n 
1 82  ARG n 
1 83  ASP n 
1 84  LEU n 
1 85  VAL n 
1 86  VAL n 
1 87  SER n 
1 88  TYR n 
1 89  VAL n 
1 90  ASN n 
1 91  THR n 
1 92  ASN n 
1 93  MET n 
1 94  GLY n 
1 95  LEU n 
1 96  LYS n 
1 97  PHE n 
1 98  ARG n 
1 99  GLN n 
1 100 LEU n 
1 101 LEU n 
1 102 TRP n 
1 103 PHE n 
1 104 HIS n 
1 105 ILE n 
1 106 SER n 
1 107 CYS n 
1 108 LEU n 
1 109 THR n 
1 110 PHE n 
1 111 GLY n 
1 112 ARG n 
1 113 GLU n 
1 114 THR n 
1 115 VAL n 
1 116 ILE n 
1 117 GLU n 
1 118 TYR n 
1 119 LEU n 
1 120 VAL n 
1 121 SER n 
1 122 PHE n 
1 123 GLY n 
1 124 VAL n 
1 125 TRP n 
1 126 ILE n 
1 127 ARG n 
1 128 THR n 
1 129 PRO n 
1 130 PRO n 
1 131 ALA n 
1 132 TYR n 
1 133 ARG n 
1 134 PRO n 
1 135 PRO n 
1 136 ASN n 
1 137 ALA n 
1 138 PRO n 
1 139 ILE n 
1 140 LEU n 
1 141 SER n 
1 142 THR n 
1 143 LEU n 
1 144 PRO n 
1 145 GLU n 
1 146 THR n 
1 147 THR n 
1 148 VAL n 
1 149 VAL n 
1 150 ARG n 
1 151 ARG n 
1 152 ARG n 
1 153 GLY n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   153 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 pre-c/core 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Hepatitis B virus' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     10407 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               human 
_entity_src_gen.pdbx_host_org_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     9606 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            HEK-293T 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   1   MET MET A . n 
A 1 2   ASP 2   2   2   ASP ASP A . n 
A 1 3   ILE 3   3   3   ILE ILE A . n 
A 1 4   ASP 4   4   4   ASP ASP A . n 
A 1 5   PRO 5   5   5   PRO PRO A . n 
A 1 6   TYR 6   6   6   TYR TYR A . n 
A 1 7   LYS 7   7   7   LYS LYS A . n 
A 1 8   GLU 8   8   8   GLU GLU A . n 
A 1 9   PHE 9   9   9   PHE PHE A . n 
A 1 10  GLY 10  10  10  GLY GLY A . n 
A 1 11  ALA 11  11  11  ALA ALA A . n 
A 1 12  THR 12  12  12  THR THR A . n 
A 1 13  VAL 13  13  13  VAL VAL A . n 
A 1 14  GLU 14  14  14  GLU GLU A . n 
A 1 15  LEU 15  15  15  LEU LEU A . n 
A 1 16  LEU 16  16  16  LEU LEU A . n 
A 1 17  SER 17  17  17  SER SER A . n 
A 1 18  PHE 18  18  18  PHE PHE A . n 
A 1 19  LEU 19  19  19  LEU LEU A . n 
A 1 20  PRO 20  20  20  PRO PRO A . n 
A 1 21  SER 21  21  21  SER SER A . n 
A 1 22  ASP 22  22  22  ASP ASP A . n 
A 1 23  PHE 23  23  23  PHE PHE A . n 
A 1 24  PHE 24  24  24  PHE PHE A . n 
A 1 25  PRO 25  25  25  PRO PRO A . n 
A 1 26  SER 26  26  26  SER SER A . n 
A 1 27  VAL 27  27  27  VAL VAL A . n 
A 1 28  ARG 28  28  28  ARG ARG A . n 
A 1 29  ASP 29  29  29  ASP ASP A . n 
A 1 30  LEU 30  30  30  LEU LEU A . n 
A 1 31  LEU 31  31  31  LEU LEU A . n 
A 1 32  ASP 32  32  32  ASP ASP A . n 
A 1 33  THR 33  33  33  THR THR A . n 
A 1 34  ALA 34  34  34  ALA ALA A . n 
A 1 35  SER 35  35  35  SER SER A . n 
A 1 36  ALA 36  36  36  ALA ALA A . n 
A 1 37  LEU 37  37  37  LEU LEU A . n 
A 1 38  TYR 38  38  38  TYR TYR A . n 
A 1 39  ARG 39  39  39  ARG ARG A . n 
A 1 40  GLU 40  40  40  GLU GLU A . n 
A 1 41  ALA 41  41  41  ALA ALA A . n 
A 1 42  LEU 42  42  42  LEU LEU A . n 
A 1 43  GLU 43  43  43  GLU GLU A . n 
A 1 44  SER 44  44  44  SER SER A . n 
A 1 45  PRO 45  45  45  PRO PRO A . n 
A 1 46  GLU 46  46  46  GLU GLU A . n 
A 1 47  HIS 47  47  47  HIS HIS A . n 
A 1 48  CYS 48  48  48  CYS CYS A . n 
A 1 49  SER 49  49  49  SER SER A . n 
A 1 50  PRO 50  50  50  PRO PRO A . n 
A 1 51  HIS 51  51  51  HIS HIS A . n 
A 1 52  HIS 52  52  52  HIS HIS A . n 
A 1 53  THR 53  53  53  THR THR A . n 
A 1 54  ALA 54  54  54  ALA ALA A . n 
A 1 55  LEU 55  55  55  LEU LEU A . n 
A 1 56  ARG 56  56  56  ARG ARG A . n 
A 1 57  GLN 57  57  57  GLN GLN A . n 
A 1 58  ALA 58  58  58  ALA ALA A . n 
A 1 59  ILE 59  59  59  ILE ILE A . n 
A 1 60  LEU 60  60  60  LEU LEU A . n 
A 1 61  CYS 61  61  61  CYS CYS A . n 
A 1 62  TRP 62  62  62  TRP TRP A . n 
A 1 63  GLY 63  63  63  GLY GLY A . n 
A 1 64  GLU 64  64  64  GLU GLU A . n 
A 1 65  LEU 65  65  65  LEU LEU A . n 
A 1 66  MET 66  66  66  MET MET A . n 
A 1 67  THR 67  67  67  THR THR A . n 
A 1 68  LEU 68  68  68  LEU LEU A . n 
A 1 69  ALA 69  69  69  ALA ALA A . n 
A 1 70  THR 70  70  70  THR THR A . n 
A 1 71  TRP 71  71  71  TRP TRP A . n 
A 1 72  VAL 72  72  72  VAL VAL A . n 
A 1 73  GLY 73  73  73  GLY GLY A . n 
A 1 74  VAL 74  74  74  VAL VAL A . n 
A 1 75  ASN 75  75  75  ASN ASN A . n 
A 1 76  LEU 76  76  76  LEU LEU A . n 
A 1 77  GLU 77  77  77  GLU GLU A . n 
A 1 78  ASP 78  78  78  ASP ASP A . n 
A 1 79  PRO 79  79  79  PRO PRO A . n 
A 1 80  ALA 80  80  80  ALA ALA A . n 
A 1 81  SER 81  81  81  SER SER A . n 
A 1 82  ARG 82  82  82  ARG ARG A . n 
A 1 83  ASP 83  83  83  ASP ASP A . n 
A 1 84  LEU 84  84  84  LEU LEU A . n 
A 1 85  VAL 85  85  85  VAL VAL A . n 
A 1 86  VAL 86  86  86  VAL VAL A . n 
A 1 87  SER 87  87  87  SER SER A . n 
A 1 88  TYR 88  88  88  TYR TYR A . n 
A 1 89  VAL 89  89  89  VAL VAL A . n 
A 1 90  ASN 90  90  90  ASN ASN A . n 
A 1 91  THR 91  91  91  THR THR A . n 
A 1 92  ASN 92  92  92  ASN ASN A . n 
A 1 93  MET 93  93  93  MET MET A . n 
A 1 94  GLY 94  94  94  GLY GLY A . n 
A 1 95  LEU 95  95  95  LEU LEU A . n 
A 1 96  LYS 96  96  96  LYS LYS A . n 
A 1 97  PHE 97  97  97  PHE PHE A . n 
A 1 98  ARG 98  98  98  ARG ARG A . n 
A 1 99  GLN 99  99  99  GLN GLN A . n 
A 1 100 LEU 100 100 100 LEU LEU A . n 
A 1 101 LEU 101 101 101 LEU LEU A . n 
A 1 102 TRP 102 102 102 TRP TRP A . n 
A 1 103 PHE 103 103 103 PHE PHE A . n 
A 1 104 HIS 104 104 104 HIS HIS A . n 
A 1 105 ILE 105 105 105 ILE ILE A . n 
A 1 106 SER 106 106 106 SER SER A . n 
A 1 107 CYS 107 107 107 CYS CYS A . n 
A 1 108 LEU 108 108 108 LEU LEU A . n 
A 1 109 THR 109 109 109 THR THR A . n 
A 1 110 PHE 110 110 110 PHE PHE A . n 
A 1 111 GLY 111 111 111 GLY GLY A . n 
A 1 112 ARG 112 112 112 ARG ARG A . n 
A 1 113 GLU 113 113 113 GLU GLU A . n 
A 1 114 THR 114 114 114 THR THR A . n 
A 1 115 VAL 115 115 115 VAL VAL A . n 
A 1 116 ILE 116 116 116 ILE ILE A . n 
A 1 117 GLU 117 117 117 GLU GLU A . n 
A 1 118 TYR 118 118 118 TYR TYR A . n 
A 1 119 LEU 119 119 119 LEU LEU A . n 
A 1 120 VAL 120 120 120 VAL VAL A . n 
A 1 121 SER 121 121 121 SER SER A . n 
A 1 122 PHE 122 122 122 PHE PHE A . n 
A 1 123 GLY 123 123 123 GLY GLY A . n 
A 1 124 VAL 124 124 124 VAL VAL A . n 
A 1 125 TRP 125 125 125 TRP TRP A . n 
A 1 126 ILE 126 126 126 ILE ILE A . n 
A 1 127 ARG 127 127 127 ARG ARG A . n 
A 1 128 THR 128 128 128 THR THR A . n 
A 1 129 PRO 129 129 129 PRO PRO A . n 
A 1 130 PRO 130 130 130 PRO PRO A . n 
A 1 131 ALA 131 131 131 ALA ALA A . n 
A 1 132 TYR 132 132 132 TYR TYR A . n 
A 1 133 ARG 133 133 133 ARG ARG A . n 
A 1 134 PRO 134 134 134 PRO PRO A . n 
A 1 135 PRO 135 135 135 PRO PRO A . n 
A 1 136 ASN 136 136 136 ASN ASN A . n 
A 1 137 ALA 137 137 137 ALA ALA A . n 
A 1 138 PRO 138 138 138 PRO PRO A . n 
A 1 139 ILE 139 139 139 ILE ILE A . n 
A 1 140 LEU 140 140 140 LEU LEU A . n 
A 1 141 SER 141 141 141 SER SER A . n 
A 1 142 THR 142 142 142 THR THR A . n 
A 1 143 LEU 143 143 143 LEU LEU A . n 
A 1 144 PRO 144 144 144 PRO PRO A . n 
A 1 145 GLU 145 145 ?   ?   ?   A . n 
A 1 146 THR 146 146 ?   ?   ?   A . n 
A 1 147 THR 147 147 ?   ?   ?   A . n 
A 1 148 VAL 148 148 ?   ?   ?   A . n 
A 1 149 VAL 149 149 ?   ?   ?   A . n 
A 1 150 ARG 150 150 ?   ?   ?   A . n 
A 1 151 ARG 151 151 ?   ?   ?   A . n 
A 1 152 ARG 152 152 ?   ?   ?   A . n 
A 1 153 GLY 153 153 ?   ?   ?   A . n 
B 1 1   MET 1   1   1   MET MET B . n 
B 1 2   ASP 2   2   2   ASP ASP B . n 
B 1 3   ILE 3   3   3   ILE ILE B . n 
B 1 4   ASP 4   4   4   ASP ASP B . n 
B 1 5   PRO 5   5   5   PRO PRO B . n 
B 1 6   TYR 6   6   6   TYR TYR B . n 
B 1 7   LYS 7   7   7   LYS LYS B . n 
B 1 8   GLU 8   8   8   GLU GLU B . n 
B 1 9   PHE 9   9   9   PHE PHE B . n 
B 1 10  GLY 10  10  10  GLY GLY B . n 
B 1 11  ALA 11  11  11  ALA ALA B . n 
B 1 12  THR 12  12  12  THR THR B . n 
B 1 13  VAL 13  13  13  VAL VAL B . n 
B 1 14  GLU 14  14  14  GLU GLU B . n 
B 1 15  LEU 15  15  15  LEU LEU B . n 
B 1 16  LEU 16  16  16  LEU LEU B . n 
B 1 17  SER 17  17  17  SER SER B . n 
B 1 18  PHE 18  18  18  PHE PHE B . n 
B 1 19  LEU 19  19  19  LEU LEU B . n 
B 1 20  PRO 20  20  20  PRO PRO B . n 
B 1 21  SER 21  21  21  SER SER B . n 
B 1 22  ASP 22  22  22  ASP ASP B . n 
B 1 23  PHE 23  23  23  PHE PHE B . n 
B 1 24  PHE 24  24  24  PHE PHE B . n 
B 1 25  PRO 25  25  25  PRO PRO B . n 
B 1 26  SER 26  26  26  SER SER B . n 
B 1 27  VAL 27  27  27  VAL VAL B . n 
B 1 28  ARG 28  28  28  ARG ARG B . n 
B 1 29  ASP 29  29  29  ASP ASP B . n 
B 1 30  LEU 30  30  30  LEU LEU B . n 
B 1 31  LEU 31  31  31  LEU LEU B . n 
B 1 32  ASP 32  32  32  ASP ASP B . n 
B 1 33  THR 33  33  33  THR THR B . n 
B 1 34  ALA 34  34  34  ALA ALA B . n 
B 1 35  SER 35  35  35  SER SER B . n 
B 1 36  ALA 36  36  36  ALA ALA B . n 
B 1 37  LEU 37  37  37  LEU LEU B . n 
B 1 38  TYR 38  38  38  TYR TYR B . n 
B 1 39  ARG 39  39  39  ARG ARG B . n 
B 1 40  GLU 40  40  40  GLU GLU B . n 
B 1 41  ALA 41  41  41  ALA ALA B . n 
B 1 42  LEU 42  42  42  LEU LEU B . n 
B 1 43  GLU 43  43  43  GLU GLU B . n 
B 1 44  SER 44  44  44  SER SER B . n 
B 1 45  PRO 45  45  45  PRO PRO B . n 
B 1 46  GLU 46  46  46  GLU GLU B . n 
B 1 47  HIS 47  47  47  HIS HIS B . n 
B 1 48  CYS 48  48  48  CYS CYS B . n 
B 1 49  SER 49  49  49  SER SER B . n 
B 1 50  PRO 50  50  50  PRO PRO B . n 
B 1 51  HIS 51  51  51  HIS HIS B . n 
B 1 52  HIS 52  52  52  HIS HIS B . n 
B 1 53  THR 53  53  53  THR THR B . n 
B 1 54  ALA 54  54  54  ALA ALA B . n 
B 1 55  LEU 55  55  55  LEU LEU B . n 
B 1 56  ARG 56  56  56  ARG ARG B . n 
B 1 57  GLN 57  57  57  GLN GLN B . n 
B 1 58  ALA 58  58  58  ALA ALA B . n 
B 1 59  ILE 59  59  59  ILE ILE B . n 
B 1 60  LEU 60  60  60  LEU LEU B . n 
B 1 61  CYS 61  61  61  CYS CYS B . n 
B 1 62  TRP 62  62  62  TRP TRP B . n 
B 1 63  GLY 63  63  63  GLY GLY B . n 
B 1 64  GLU 64  64  64  GLU GLU B . n 
B 1 65  LEU 65  65  65  LEU LEU B . n 
B 1 66  MET 66  66  66  MET MET B . n 
B 1 67  THR 67  67  67  THR THR B . n 
B 1 68  LEU 68  68  68  LEU LEU B . n 
B 1 69  ALA 69  69  69  ALA ALA B . n 
B 1 70  THR 70  70  70  THR THR B . n 
B 1 71  TRP 71  71  71  TRP TRP B . n 
B 1 72  VAL 72  72  72  VAL VAL B . n 
B 1 73  GLY 73  73  73  GLY GLY B . n 
B 1 74  VAL 74  74  74  VAL VAL B . n 
B 1 75  ASN 75  75  75  ASN ASN B . n 
B 1 76  LEU 76  76  76  LEU LEU B . n 
B 1 77  GLU 77  77  77  GLU GLU B . n 
B 1 78  ASP 78  78  78  ASP ASP B . n 
B 1 79  PRO 79  79  79  PRO PRO B . n 
B 1 80  ALA 80  80  80  ALA ALA B . n 
B 1 81  SER 81  81  81  SER SER B . n 
B 1 82  ARG 82  82  82  ARG ARG B . n 
B 1 83  ASP 83  83  83  ASP ASP B . n 
B 1 84  LEU 84  84  84  LEU LEU B . n 
B 1 85  VAL 85  85  85  VAL VAL B . n 
B 1 86  VAL 86  86  86  VAL VAL B . n 
B 1 87  SER 87  87  87  SER SER B . n 
B 1 88  TYR 88  88  88  TYR TYR B . n 
B 1 89  VAL 89  89  89  VAL VAL B . n 
B 1 90  ASN 90  90  90  ASN ASN B . n 
B 1 91  THR 91  91  91  THR THR B . n 
B 1 92  ASN 92  92  92  ASN ASN B . n 
B 1 93  MET 93  93  93  MET MET B . n 
B 1 94  GLY 94  94  94  GLY GLY B . n 
B 1 95  LEU 95  95  95  LEU LEU B . n 
B 1 96  LYS 96  96  96  LYS LYS B . n 
B 1 97  PHE 97  97  97  PHE PHE B . n 
B 1 98  ARG 98  98  98  ARG ARG B . n 
B 1 99  GLN 99  99  99  GLN GLN B . n 
B 1 100 LEU 100 100 100 LEU LEU B . n 
B 1 101 LEU 101 101 101 LEU LEU B . n 
B 1 102 TRP 102 102 102 TRP TRP B . n 
B 1 103 PHE 103 103 103 PHE PHE B . n 
B 1 104 HIS 104 104 104 HIS HIS B . n 
B 1 105 ILE 105 105 105 ILE ILE B . n 
B 1 106 SER 106 106 106 SER SER B . n 
B 1 107 CYS 107 107 107 CYS CYS B . n 
B 1 108 LEU 108 108 108 LEU LEU B . n 
B 1 109 THR 109 109 109 THR THR B . n 
B 1 110 PHE 110 110 110 PHE PHE B . n 
B 1 111 GLY 111 111 111 GLY GLY B . n 
B 1 112 ARG 112 112 112 ARG ARG B . n 
B 1 113 GLU 113 113 113 GLU GLU B . n 
B 1 114 THR 114 114 114 THR THR B . n 
B 1 115 VAL 115 115 115 VAL VAL B . n 
B 1 116 ILE 116 116 116 ILE ILE B . n 
B 1 117 GLU 117 117 117 GLU GLU B . n 
B 1 118 TYR 118 118 118 TYR TYR B . n 
B 1 119 LEU 119 119 119 LEU LEU B . n 
B 1 120 VAL 120 120 120 VAL VAL B . n 
B 1 121 SER 121 121 121 SER SER B . n 
B 1 122 PHE 122 122 122 PHE PHE B . n 
B 1 123 GLY 123 123 123 GLY GLY B . n 
B 1 124 VAL 124 124 124 VAL VAL B . n 
B 1 125 TRP 125 125 125 TRP TRP B . n 
B 1 126 ILE 126 126 126 ILE ILE B . n 
B 1 127 ARG 127 127 127 ARG ARG B . n 
B 1 128 THR 128 128 128 THR THR B . n 
B 1 129 PRO 129 129 129 PRO PRO B . n 
B 1 130 PRO 130 130 130 PRO PRO B . n 
B 1 131 ALA 131 131 131 ALA ALA B . n 
B 1 132 TYR 132 132 132 TYR TYR B . n 
B 1 133 ARG 133 133 133 ARG ARG B . n 
B 1 134 PRO 134 134 134 PRO PRO B . n 
B 1 135 PRO 135 135 135 PRO PRO B . n 
B 1 136 ASN 136 136 136 ASN ASN B . n 
B 1 137 ALA 137 137 137 ALA ALA B . n 
B 1 138 PRO 138 138 138 PRO PRO B . n 
B 1 139 ILE 139 139 139 ILE ILE B . n 
B 1 140 LEU 140 140 140 LEU LEU B . n 
B 1 141 SER 141 141 141 SER SER B . n 
B 1 142 THR 142 142 142 THR THR B . n 
B 1 143 LEU 143 143 143 LEU LEU B . n 
B 1 144 PRO 144 144 144 PRO PRO B . n 
B 1 145 GLU 145 145 145 GLU GLU B . n 
B 1 146 THR 146 146 146 THR THR B . n 
B 1 147 THR 147 147 147 THR THR B . n 
B 1 148 VAL 148 148 148 VAL VAL B . n 
B 1 149 VAL 149 149 149 VAL VAL B . n 
B 1 150 ARG 150 150 150 ARG ARG B . n 
B 1 151 ARG 151 151 151 ARG ARG B . n 
B 1 152 ARG 152 152 152 ARG ARG B . n 
B 1 153 GLY 153 153 153 GLY GLY B . n 
C 1 1   MET 1   1   1   MET MET C . n 
C 1 2   ASP 2   2   2   ASP ASP C . n 
C 1 3   ILE 3   3   3   ILE ILE C . n 
C 1 4   ASP 4   4   4   ASP ASP C . n 
C 1 5   PRO 5   5   5   PRO PRO C . n 
C 1 6   TYR 6   6   6   TYR TYR C . n 
C 1 7   LYS 7   7   7   LYS LYS C . n 
C 1 8   GLU 8   8   8   GLU GLU C . n 
C 1 9   PHE 9   9   9   PHE PHE C . n 
C 1 10  GLY 10  10  10  GLY GLY C . n 
C 1 11  ALA 11  11  11  ALA ALA C . n 
C 1 12  THR 12  12  12  THR THR C . n 
C 1 13  VAL 13  13  13  VAL VAL C . n 
C 1 14  GLU 14  14  14  GLU GLU C . n 
C 1 15  LEU 15  15  15  LEU LEU C . n 
C 1 16  LEU 16  16  16  LEU LEU C . n 
C 1 17  SER 17  17  17  SER SER C . n 
C 1 18  PHE 18  18  18  PHE PHE C . n 
C 1 19  LEU 19  19  19  LEU LEU C . n 
C 1 20  PRO 20  20  20  PRO PRO C . n 
C 1 21  SER 21  21  21  SER SER C . n 
C 1 22  ASP 22  22  22  ASP ASP C . n 
C 1 23  PHE 23  23  23  PHE PHE C . n 
C 1 24  PHE 24  24  24  PHE PHE C . n 
C 1 25  PRO 25  25  25  PRO PRO C . n 
C 1 26  SER 26  26  26  SER SER C . n 
C 1 27  VAL 27  27  27  VAL VAL C . n 
C 1 28  ARG 28  28  28  ARG ARG C . n 
C 1 29  ASP 29  29  29  ASP ASP C . n 
C 1 30  LEU 30  30  30  LEU LEU C . n 
C 1 31  LEU 31  31  31  LEU LEU C . n 
C 1 32  ASP 32  32  32  ASP ASP C . n 
C 1 33  THR 33  33  33  THR THR C . n 
C 1 34  ALA 34  34  34  ALA ALA C . n 
C 1 35  SER 35  35  35  SER SER C . n 
C 1 36  ALA 36  36  36  ALA ALA C . n 
C 1 37  LEU 37  37  37  LEU LEU C . n 
C 1 38  TYR 38  38  38  TYR TYR C . n 
C 1 39  ARG 39  39  39  ARG ARG C . n 
C 1 40  GLU 40  40  40  GLU GLU C . n 
C 1 41  ALA 41  41  41  ALA ALA C . n 
C 1 42  LEU 42  42  42  LEU LEU C . n 
C 1 43  GLU 43  43  43  GLU GLU C . n 
C 1 44  SER 44  44  44  SER SER C . n 
C 1 45  PRO 45  45  45  PRO PRO C . n 
C 1 46  GLU 46  46  46  GLU GLU C . n 
C 1 47  HIS 47  47  47  HIS HIS C . n 
C 1 48  CYS 48  48  48  CYS CYS C . n 
C 1 49  SER 49  49  49  SER SER C . n 
C 1 50  PRO 50  50  50  PRO PRO C . n 
C 1 51  HIS 51  51  51  HIS HIS C . n 
C 1 52  HIS 52  52  52  HIS HIS C . n 
C 1 53  THR 53  53  53  THR THR C . n 
C 1 54  ALA 54  54  54  ALA ALA C . n 
C 1 55  LEU 55  55  55  LEU LEU C . n 
C 1 56  ARG 56  56  56  ARG ARG C . n 
C 1 57  GLN 57  57  57  GLN GLN C . n 
C 1 58  ALA 58  58  58  ALA ALA C . n 
C 1 59  ILE 59  59  59  ILE ILE C . n 
C 1 60  LEU 60  60  60  LEU LEU C . n 
C 1 61  CYS 61  61  61  CYS CYS C . n 
C 1 62  TRP 62  62  62  TRP TRP C . n 
C 1 63  GLY 63  63  63  GLY GLY C . n 
C 1 64  GLU 64  64  64  GLU GLU C . n 
C 1 65  LEU 65  65  65  LEU LEU C . n 
C 1 66  MET 66  66  66  MET MET C . n 
C 1 67  THR 67  67  67  THR THR C . n 
C 1 68  LEU 68  68  68  LEU LEU C . n 
C 1 69  ALA 69  69  69  ALA ALA C . n 
C 1 70  THR 70  70  70  THR THR C . n 
C 1 71  TRP 71  71  71  TRP TRP C . n 
C 1 72  VAL 72  72  72  VAL VAL C . n 
C 1 73  GLY 73  73  73  GLY GLY C . n 
C 1 74  VAL 74  74  74  VAL VAL C . n 
C 1 75  ASN 75  75  75  ASN ASN C . n 
C 1 76  LEU 76  76  76  LEU LEU C . n 
C 1 77  GLU 77  77  77  GLU GLU C . n 
C 1 78  ASP 78  78  78  ASP ASP C . n 
C 1 79  PRO 79  79  79  PRO PRO C . n 
C 1 80  ALA 80  80  80  ALA ALA C . n 
C 1 81  SER 81  81  81  SER SER C . n 
C 1 82  ARG 82  82  82  ARG ARG C . n 
C 1 83  ASP 83  83  83  ASP ASP C . n 
C 1 84  LEU 84  84  84  LEU LEU C . n 
C 1 85  VAL 85  85  85  VAL VAL C . n 
C 1 86  VAL 86  86  86  VAL VAL C . n 
C 1 87  SER 87  87  87  SER SER C . n 
C 1 88  TYR 88  88  88  TYR TYR C . n 
C 1 89  VAL 89  89  89  VAL VAL C . n 
C 1 90  ASN 90  90  90  ASN ASN C . n 
C 1 91  THR 91  91  91  THR THR C . n 
C 1 92  ASN 92  92  92  ASN ASN C . n 
C 1 93  MET 93  93  93  MET MET C . n 
C 1 94  GLY 94  94  94  GLY GLY C . n 
C 1 95  LEU 95  95  95  LEU LEU C . n 
C 1 96  LYS 96  96  96  LYS LYS C . n 
C 1 97  PHE 97  97  97  PHE PHE C . n 
C 1 98  ARG 98  98  98  ARG ARG C . n 
C 1 99  GLN 99  99  99  GLN GLN C . n 
C 1 100 LEU 100 100 100 LEU LEU C . n 
C 1 101 LEU 101 101 101 LEU LEU C . n 
C 1 102 TRP 102 102 102 TRP TRP C . n 
C 1 103 PHE 103 103 103 PHE PHE C . n 
C 1 104 HIS 104 104 104 HIS HIS C . n 
C 1 105 ILE 105 105 105 ILE ILE C . n 
C 1 106 SER 106 106 106 SER SER C . n 
C 1 107 CYS 107 107 107 CYS CYS C . n 
C 1 108 LEU 108 108 108 LEU LEU C . n 
C 1 109 THR 109 109 109 THR THR C . n 
C 1 110 PHE 110 110 110 PHE PHE C . n 
C 1 111 GLY 111 111 111 GLY GLY C . n 
C 1 112 ARG 112 112 112 ARG ARG C . n 
C 1 113 GLU 113 113 113 GLU GLU C . n 
C 1 114 THR 114 114 114 THR THR C . n 
C 1 115 VAL 115 115 115 VAL VAL C . n 
C 1 116 ILE 116 116 116 ILE ILE C . n 
C 1 117 GLU 117 117 117 GLU GLU C . n 
C 1 118 TYR 118 118 118 TYR TYR C . n 
C 1 119 LEU 119 119 119 LEU LEU C . n 
C 1 120 VAL 120 120 120 VAL VAL C . n 
C 1 121 SER 121 121 121 SER SER C . n 
C 1 122 PHE 122 122 122 PHE PHE C . n 
C 1 123 GLY 123 123 123 GLY GLY C . n 
C 1 124 VAL 124 124 124 VAL VAL C . n 
C 1 125 TRP 125 125 125 TRP TRP C . n 
C 1 126 ILE 126 126 126 ILE ILE C . n 
C 1 127 ARG 127 127 127 ARG ARG C . n 
C 1 128 THR 128 128 128 THR THR C . n 
C 1 129 PRO 129 129 129 PRO PRO C . n 
C 1 130 PRO 130 130 130 PRO PRO C . n 
C 1 131 ALA 131 131 131 ALA ALA C . n 
C 1 132 TYR 132 132 132 TYR TYR C . n 
C 1 133 ARG 133 133 133 ARG ARG C . n 
C 1 134 PRO 134 134 134 PRO PRO C . n 
C 1 135 PRO 135 135 135 PRO PRO C . n 
C 1 136 ASN 136 136 136 ASN ASN C . n 
C 1 137 ALA 137 137 137 ALA ALA C . n 
C 1 138 PRO 138 138 138 PRO PRO C . n 
C 1 139 ILE 139 139 139 ILE ILE C . n 
C 1 140 LEU 140 140 140 LEU LEU C . n 
C 1 141 SER 141 141 141 SER SER C . n 
C 1 142 THR 142 142 142 THR THR C . n 
C 1 143 LEU 143 143 143 LEU LEU C . n 
C 1 144 PRO 144 144 144 PRO PRO C . n 
C 1 145 GLU 145 145 145 GLU GLU C . n 
C 1 146 THR 146 146 146 THR THR C . n 
C 1 147 THR 147 147 ?   ?   ?   C . n 
C 1 148 VAL 148 148 ?   ?   ?   C . n 
C 1 149 VAL 149 149 ?   ?   ?   C . n 
C 1 150 ARG 150 150 ?   ?   ?   C . n 
C 1 151 ARG 151 151 ?   ?   ?   C . n 
C 1 152 ARG 152 152 ?   ?   ?   C . n 
C 1 153 GLY 153 153 ?   ?   ?   C . n 
D 1 1   MET 1   1   1   MET MET D . n 
D 1 2   ASP 2   2   2   ASP ASP D . n 
D 1 3   ILE 3   3   3   ILE ILE D . n 
D 1 4   ASP 4   4   4   ASP ASP D . n 
D 1 5   PRO 5   5   5   PRO PRO D . n 
D 1 6   TYR 6   6   6   TYR TYR D . n 
D 1 7   LYS 7   7   7   LYS LYS D . n 
D 1 8   GLU 8   8   8   GLU GLU D . n 
D 1 9   PHE 9   9   9   PHE PHE D . n 
D 1 10  GLY 10  10  10  GLY GLY D . n 
D 1 11  ALA 11  11  11  ALA ALA D . n 
D 1 12  THR 12  12  12  THR THR D . n 
D 1 13  VAL 13  13  13  VAL VAL D . n 
D 1 14  GLU 14  14  14  GLU GLU D . n 
D 1 15  LEU 15  15  15  LEU LEU D . n 
D 1 16  LEU 16  16  16  LEU LEU D . n 
D 1 17  SER 17  17  17  SER SER D . n 
D 1 18  PHE 18  18  18  PHE PHE D . n 
D 1 19  LEU 19  19  19  LEU LEU D . n 
D 1 20  PRO 20  20  20  PRO PRO D . n 
D 1 21  SER 21  21  21  SER SER D . n 
D 1 22  ASP 22  22  22  ASP ASP D . n 
D 1 23  PHE 23  23  23  PHE PHE D . n 
D 1 24  PHE 24  24  24  PHE PHE D . n 
D 1 25  PRO 25  25  25  PRO PRO D . n 
D 1 26  SER 26  26  26  SER SER D . n 
D 1 27  VAL 27  27  27  VAL VAL D . n 
D 1 28  ARG 28  28  28  ARG ARG D . n 
D 1 29  ASP 29  29  29  ASP ASP D . n 
D 1 30  LEU 30  30  30  LEU LEU D . n 
D 1 31  LEU 31  31  31  LEU LEU D . n 
D 1 32  ASP 32  32  32  ASP ASP D . n 
D 1 33  THR 33  33  33  THR THR D . n 
D 1 34  ALA 34  34  34  ALA ALA D . n 
D 1 35  SER 35  35  35  SER SER D . n 
D 1 36  ALA 36  36  36  ALA ALA D . n 
D 1 37  LEU 37  37  37  LEU LEU D . n 
D 1 38  TYR 38  38  38  TYR TYR D . n 
D 1 39  ARG 39  39  39  ARG ARG D . n 
D 1 40  GLU 40  40  40  GLU GLU D . n 
D 1 41  ALA 41  41  41  ALA ALA D . n 
D 1 42  LEU 42  42  42  LEU LEU D . n 
D 1 43  GLU 43  43  43  GLU GLU D . n 
D 1 44  SER 44  44  44  SER SER D . n 
D 1 45  PRO 45  45  45  PRO PRO D . n 
D 1 46  GLU 46  46  46  GLU GLU D . n 
D 1 47  HIS 47  47  47  HIS HIS D . n 
D 1 48  CYS 48  48  48  CYS CYS D . n 
D 1 49  SER 49  49  49  SER SER D . n 
D 1 50  PRO 50  50  50  PRO PRO D . n 
D 1 51  HIS 51  51  51  HIS HIS D . n 
D 1 52  HIS 52  52  52  HIS HIS D . n 
D 1 53  THR 53  53  53  THR THR D . n 
D 1 54  ALA 54  54  54  ALA ALA D . n 
D 1 55  LEU 55  55  55  LEU LEU D . n 
D 1 56  ARG 56  56  56  ARG ARG D . n 
D 1 57  GLN 57  57  57  GLN GLN D . n 
D 1 58  ALA 58  58  58  ALA ALA D . n 
D 1 59  ILE 59  59  59  ILE ILE D . n 
D 1 60  LEU 60  60  60  LEU LEU D . n 
D 1 61  CYS 61  61  61  CYS CYS D . n 
D 1 62  TRP 62  62  62  TRP TRP D . n 
D 1 63  GLY 63  63  63  GLY GLY D . n 
D 1 64  GLU 64  64  64  GLU GLU D . n 
D 1 65  LEU 65  65  65  LEU LEU D . n 
D 1 66  MET 66  66  66  MET MET D . n 
D 1 67  THR 67  67  67  THR THR D . n 
D 1 68  LEU 68  68  68  LEU LEU D . n 
D 1 69  ALA 69  69  69  ALA ALA D . n 
D 1 70  THR 70  70  70  THR THR D . n 
D 1 71  TRP 71  71  71  TRP TRP D . n 
D 1 72  VAL 72  72  72  VAL VAL D . n 
D 1 73  GLY 73  73  73  GLY GLY D . n 
D 1 74  VAL 74  74  74  VAL VAL D . n 
D 1 75  ASN 75  75  75  ASN ASN D . n 
D 1 76  LEU 76  76  76  LEU LEU D . n 
D 1 77  GLU 77  77  77  GLU GLU D . n 
D 1 78  ASP 78  78  78  ASP ASP D . n 
D 1 79  PRO 79  79  79  PRO PRO D . n 
D 1 80  ALA 80  80  80  ALA ALA D . n 
D 1 81  SER 81  81  81  SER SER D . n 
D 1 82  ARG 82  82  82  ARG ARG D . n 
D 1 83  ASP 83  83  83  ASP ASP D . n 
D 1 84  LEU 84  84  84  LEU LEU D . n 
D 1 85  VAL 85  85  85  VAL VAL D . n 
D 1 86  VAL 86  86  86  VAL VAL D . n 
D 1 87  SER 87  87  87  SER SER D . n 
D 1 88  TYR 88  88  88  TYR TYR D . n 
D 1 89  VAL 89  89  89  VAL VAL D . n 
D 1 90  ASN 90  90  90  ASN ASN D . n 
D 1 91  THR 91  91  91  THR THR D . n 
D 1 92  ASN 92  92  92  ASN ASN D . n 
D 1 93  MET 93  93  93  MET MET D . n 
D 1 94  GLY 94  94  94  GLY GLY D . n 
D 1 95  LEU 95  95  95  LEU LEU D . n 
D 1 96  LYS 96  96  96  LYS LYS D . n 
D 1 97  PHE 97  97  97  PHE PHE D . n 
D 1 98  ARG 98  98  98  ARG ARG D . n 
D 1 99  GLN 99  99  99  GLN GLN D . n 
D 1 100 LEU 100 100 100 LEU LEU D . n 
D 1 101 LEU 101 101 101 LEU LEU D . n 
D 1 102 TRP 102 102 102 TRP TRP D . n 
D 1 103 PHE 103 103 103 PHE PHE D . n 
D 1 104 HIS 104 104 104 HIS HIS D . n 
D 1 105 ILE 105 105 105 ILE ILE D . n 
D 1 106 SER 106 106 106 SER SER D . n 
D 1 107 CYS 107 107 107 CYS CYS D . n 
D 1 108 LEU 108 108 108 LEU LEU D . n 
D 1 109 THR 109 109 109 THR THR D . n 
D 1 110 PHE 110 110 110 PHE PHE D . n 
D 1 111 GLY 111 111 111 GLY GLY D . n 
D 1 112 ARG 112 112 112 ARG ARG D . n 
D 1 113 GLU 113 113 113 GLU GLU D . n 
D 1 114 THR 114 114 114 THR THR D . n 
D 1 115 VAL 115 115 115 VAL VAL D . n 
D 1 116 ILE 116 116 116 ILE ILE D . n 
D 1 117 GLU 117 117 117 GLU GLU D . n 
D 1 118 TYR 118 118 118 TYR TYR D . n 
D 1 119 LEU 119 119 119 LEU LEU D . n 
D 1 120 VAL 120 120 120 VAL VAL D . n 
D 1 121 SER 121 121 121 SER SER D . n 
D 1 122 PHE 122 122 122 PHE PHE D . n 
D 1 123 GLY 123 123 123 GLY GLY D . n 
D 1 124 VAL 124 124 124 VAL VAL D . n 
D 1 125 TRP 125 125 125 TRP TRP D . n 
D 1 126 ILE 126 126 126 ILE ILE D . n 
D 1 127 ARG 127 127 127 ARG ARG D . n 
D 1 128 THR 128 128 128 THR THR D . n 
D 1 129 PRO 129 129 129 PRO PRO D . n 
D 1 130 PRO 130 130 130 PRO PRO D . n 
D 1 131 ALA 131 131 131 ALA ALA D . n 
D 1 132 TYR 132 132 132 TYR TYR D . n 
D 1 133 ARG 133 133 133 ARG ARG D . n 
D 1 134 PRO 134 134 134 PRO PRO D . n 
D 1 135 PRO 135 135 135 PRO PRO D . n 
D 1 136 ASN 136 136 136 ASN ASN D . n 
D 1 137 ALA 137 137 137 ALA ALA D . n 
D 1 138 PRO 138 138 138 PRO PRO D . n 
D 1 139 ILE 139 139 139 ILE ILE D . n 
D 1 140 LEU 140 140 140 LEU LEU D . n 
D 1 141 SER 141 141 141 SER SER D . n 
D 1 142 THR 142 142 142 THR THR D . n 
D 1 143 LEU 143 143 143 LEU LEU D . n 
D 1 144 PRO 144 144 144 PRO PRO D . n 
D 1 145 GLU 145 145 145 GLU GLU D . n 
D 1 146 THR 146 146 146 THR THR D . n 
D 1 147 THR 147 147 147 THR THR D . n 
D 1 148 VAL 148 148 148 VAL VAL D . n 
D 1 149 VAL 149 149 149 VAL VAL D . n 
D 1 150 ARG 150 150 150 ARG ARG D . n 
D 1 151 ARG 151 151 151 ARG ARG D . n 
D 1 152 ARG 152 152 152 ARG ARG D . n 
D 1 153 GLY 153 153 153 GLY GLY D . n 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8UYT 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8UYT 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8UYT 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_struct.entry_id                     8UYT 
_struct.title                        'HBV T=4 capsid from HEK-293T cells' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8UYT 
_struct_keywords.text            'HBV, Hepatitis B, Capsid, Core Protein, HEK-293T, VIRUS' 
_struct_keywords.pdbx_keywords   VIRUS 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 1 ? 
D N N 1 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    Q89656_HBV 
_struct_ref.pdbx_db_accession          Q89656 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MDIDPYKEFGATVELLSFLPSDFFPSVRDLLDTASALYREALESPEHCSPHHTALRQAILCWGELMTLATWVGVNLEDPA
SRDLVVSYVNTNMGLKFRQLLWFHISCLTFGRETVIEYLVSFGVWIRTPPAYRPPNAPILSTLPETTVVRRRG
;
_struct_ref.pdbx_align_begin           30 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8UYT A 1 ? 153 ? Q89656 30 ? 182 ? 1 153 
2 1 8UYT B 1 ? 153 ? Q89656 30 ? 182 ? 1 153 
3 1 8UYT C 1 ? 153 ? Q89656 30 ? 182 ? 1 153 
4 1 8UYT D 1 ? 153 ? Q89656 30 ? 182 ? 1 153 
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 'complete icosahedral assembly'                ? 240-meric   240 
2 'icosahedral asymmetric unit'                  ? tetrameric  4   
3 'icosahedral pentamer'                         ? eicosameric 20  
4 'icosahedral 23 hexamer'                       ? 24-meric    24  
5 'icosahedral asymmetric unit, std point frame' ? tetrameric  4   
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 '(1-60)'           A,B,C,D 
2 1                  A,B,C,D 
3 '(1-5)'            A,B,C,D 
4 '(1,2,6,10,23,24)' A,B,C,D 
5 P                  A,B,C,D 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
loop_
_pdbx_struct_oper_list.id 
_pdbx_struct_oper_list.type 
_pdbx_struct_oper_list.name 
_pdbx_struct_oper_list.symmetry_operation 
_pdbx_struct_oper_list.matrix[1][1] 
_pdbx_struct_oper_list.matrix[1][2] 
_pdbx_struct_oper_list.matrix[1][3] 
_pdbx_struct_oper_list.vector[1] 
_pdbx_struct_oper_list.matrix[2][1] 
_pdbx_struct_oper_list.matrix[2][2] 
_pdbx_struct_oper_list.matrix[2][3] 
_pdbx_struct_oper_list.vector[2] 
_pdbx_struct_oper_list.matrix[3][1] 
_pdbx_struct_oper_list.matrix[3][2] 
_pdbx_struct_oper_list.matrix[3][3] 
_pdbx_struct_oper_list.vector[3] 
P  'transform to point frame' ?     ?     0.00000000  1.00000000  0.00000000  0.00000 -1.00000000 0.00000000  0.00000000  0.00000 
0.00000000  0.00000000  1.00000000  0.00000 
1  'identity operation'       1_555 x,y,z 1.00000000  0.00000000  0.00000000  0.00000 0.00000000  1.00000000  0.00000000  0.00000 
0.00000000  0.00000000  1.00000000  0.00000 
2  'point symmetry operation' ?     ?     0.50000000  -0.80901699 -0.30901699 0.00000 0.80901699  0.30901699  0.50000000  0.00000 
-0.30901699 -0.50000000 0.80901699  0.00000 
3  'point symmetry operation' ?     ?     -0.30901699 -0.50000000 -0.80901699 0.00000 0.50000000  -0.80901699 0.30901699  0.00000 
-0.80901699 -0.30901699 0.50000000  0.00000 
4  'point symmetry operation' ?     ?     -0.30901699 0.50000000  -0.80901699 0.00000 -0.50000000 -0.80901699 -0.30901699 0.00000 
-0.80901699 0.30901699  0.50000000  0.00000 
5  'point symmetry operation' ?     ?     0.50000000  0.80901699  -0.30901699 0.00000 -0.80901699 0.30901699  -0.50000000 0.00000 
-0.30901699 0.50000000  0.80901699  0.00000 
6  'point symmetry operation' ?     ?     -1.00000000 0.00000000  0.00000000  0.00000 0.00000000  -1.00000000 0.00000000  0.00000 
0.00000000  0.00000000  1.00000000  0.00000 
7  'point symmetry operation' ?     ?     -0.50000000 0.80901699  0.30901699  0.00000 -0.80901699 -0.30901699 -0.50000000 0.00000 
-0.30901699 -0.50000000 0.80901699  0.00000 
8  'point symmetry operation' ?     ?     0.30901699  0.50000000  0.80901699  0.00000 -0.50000000 0.80901699  -0.30901699 0.00000 
-0.80901699 -0.30901699 0.50000000  0.00000 
9  'point symmetry operation' ?     ?     0.30901699  -0.50000000 0.80901699  0.00000 0.50000000  0.80901699  0.30901699  0.00000 
-0.80901699 0.30901699  0.50000000  0.00000 
10 'point symmetry operation' ?     ?     -0.50000000 -0.80901699 0.30901699  0.00000 0.80901699  -0.30901699 0.50000000  0.00000 
-0.30901699 0.50000000  0.80901699  0.00000 
11 'point symmetry operation' ?     ?     1.00000000  0.00000000  0.00000000  0.00000 0.00000000  -1.00000000 0.00000000  0.00000 
0.00000000  0.00000000  -1.00000000 0.00000 
12 'point symmetry operation' ?     ?     0.50000000  -0.80901699 -0.30901699 0.00000 -0.80901699 -0.30901699 -0.50000000 0.00000 
0.30901699  0.50000000  -0.80901699 0.00000 
13 'point symmetry operation' ?     ?     -0.30901699 -0.50000000 -0.80901699 0.00000 -0.50000000 0.80901699  -0.30901699 0.00000 
0.80901699  0.30901699  -0.50000000 0.00000 
14 'point symmetry operation' ?     ?     -0.30901699 0.50000000  -0.80901699 0.00000 0.50000000  0.80901699  0.30901699  0.00000 
0.80901699  -0.30901699 -0.50000000 0.00000 
15 'point symmetry operation' ?     ?     0.50000000  0.80901699  -0.30901699 0.00000 0.80901699  -0.30901699 0.50000000  0.00000 
0.30901699  -0.50000000 -0.80901699 0.00000 
16 'point symmetry operation' ?     ?     -1.00000000 0.00000000  0.00000000  0.00000 0.00000000  1.00000000  0.00000000  0.00000 
0.00000000  0.00000000  -1.00000000 0.00000 
17 'point symmetry operation' ?     ?     -0.50000000 0.80901699  0.30901699  0.00000 0.80901699  0.30901699  0.50000000  0.00000 
0.30901699  0.50000000  -0.80901699 0.00000 
18 'point symmetry operation' ?     ?     0.30901699  0.50000000  0.80901699  0.00000 0.50000000  -0.80901699 0.30901699  0.00000 
0.80901699  0.30901699  -0.50000000 0.00000 
19 'point symmetry operation' ?     ?     0.30901699  -0.50000000 0.80901699  0.00000 -0.50000000 -0.80901699 -0.30901699 0.00000 
0.80901699  -0.30901699 -0.50000000 0.00000 
20 'point symmetry operation' ?     ?     -0.50000000 -0.80901699 0.30901699  0.00000 -0.80901699 0.30901699  -0.50000000 0.00000 
0.30901699  -0.50000000 -0.80901699 0.00000 
21 'point symmetry operation' ?     ?     0.00000000  -1.00000000 0.00000000  0.00000 0.00000000  0.00000000  1.00000000  0.00000 
-1.00000000 0.00000000  0.00000000  0.00000 
22 'point symmetry operation' ?     ?     -0.80901699 -0.30901699 -0.50000000 0.00000 -0.30901699 -0.50000000 0.80901699  0.00000 
-0.50000000 0.80901699  0.30901699  0.00000 
23 'point symmetry operation' ?     ?     -0.50000000 0.80901699  -0.30901699 0.00000 -0.80901699 -0.30901699 0.50000000  0.00000 
0.30901699  0.50000000  0.80901699  0.00000 
24 'point symmetry operation' ?     ?     0.50000000  0.80901699  0.30901699  0.00000 -0.80901699 0.30901699  0.50000000  0.00000 
0.30901699  -0.50000000 0.80901699  0.00000 
25 'point symmetry operation' ?     ?     0.80901699  -0.30901699 0.50000000  0.00000 -0.30901699 0.50000000  0.80901699  0.00000 
-0.50000000 -0.80901699 0.30901699  0.00000 
26 'point symmetry operation' ?     ?     0.00000000  1.00000000  0.00000000  0.00000 0.00000000  0.00000000  1.00000000  0.00000 
1.00000000  0.00000000  0.00000000  0.00000 
27 'point symmetry operation' ?     ?     0.80901699  0.30901699  0.50000000  0.00000 -0.30901699 -0.50000000 0.80901699  0.00000 
0.50000000  -0.80901699 -0.30901699 0.00000 
28 'point symmetry operation' ?     ?     0.50000000  -0.80901699 0.30901699  0.00000 -0.80901699 -0.30901699 0.50000000  0.00000 
-0.30901699 -0.50000000 -0.80901699 0.00000 
29 'point symmetry operation' ?     ?     -0.50000000 -0.80901699 -0.30901699 0.00000 -0.80901699 0.30901699  0.50000000  0.00000 
-0.30901699 0.50000000  -0.80901699 0.00000 
30 'point symmetry operation' ?     ?     -0.80901699 0.30901699  -0.50000000 0.00000 -0.30901699 0.50000000  0.80901699  0.00000 
0.50000000  0.80901699  -0.30901699 0.00000 
31 'point symmetry operation' ?     ?     0.00000000  1.00000000  0.00000000  0.00000 0.00000000  0.00000000  -1.00000000 0.00000 
-1.00000000 0.00000000  0.00000000  0.00000 
32 'point symmetry operation' ?     ?     0.80901699  0.30901699  0.50000000  0.00000 0.30901699  0.50000000  -0.80901699 0.00000 
-0.50000000 0.80901699  0.30901699  0.00000 
33 'point symmetry operation' ?     ?     0.50000000  -0.80901699 0.30901699  0.00000 0.80901699  0.30901699  -0.50000000 0.00000 
0.30901699  0.50000000  0.80901699  0.00000 
34 'point symmetry operation' ?     ?     -0.50000000 -0.80901699 -0.30901699 0.00000 0.80901699  -0.30901699 -0.50000000 0.00000 
0.30901699  -0.50000000 0.80901699  0.00000 
35 'point symmetry operation' ?     ?     -0.80901699 0.30901699  -0.50000000 0.00000 0.30901699  -0.50000000 -0.80901699 0.00000 
-0.50000000 -0.80901699 0.30901699  0.00000 
36 'point symmetry operation' ?     ?     0.00000000  -1.00000000 0.00000000  0.00000 0.00000000  0.00000000  -1.00000000 0.00000 
1.00000000  0.00000000  0.00000000  0.00000 
37 'point symmetry operation' ?     ?     -0.80901699 -0.30901699 -0.50000000 0.00000 0.30901699  0.50000000  -0.80901699 0.00000 
0.50000000  -0.80901699 -0.30901699 0.00000 
38 'point symmetry operation' ?     ?     -0.50000000 0.80901699  -0.30901699 0.00000 0.80901699  0.30901699  -0.50000000 0.00000 
-0.30901699 -0.50000000 -0.80901699 0.00000 
39 'point symmetry operation' ?     ?     0.50000000  0.80901699  0.30901699  0.00000 0.80901699  -0.30901699 -0.50000000 0.00000 
-0.30901699 0.50000000  -0.80901699 0.00000 
40 'point symmetry operation' ?     ?     0.80901699  -0.30901699 0.50000000  0.00000 0.30901699  -0.50000000 -0.80901699 0.00000 
0.50000000  0.80901699  -0.30901699 0.00000 
41 'point symmetry operation' ?     ?     0.00000000  0.00000000  -1.00000000 0.00000 -1.00000000 0.00000000  0.00000000  0.00000 
0.00000000  1.00000000  0.00000000  0.00000 
42 'point symmetry operation' ?     ?     0.30901699  0.50000000  -0.80901699 0.00000 -0.50000000 0.80901699  0.30901699  0.00000 
0.80901699  0.30901699  0.50000000  0.00000 
43 'point symmetry operation' ?     ?     0.80901699  0.30901699  -0.50000000 0.00000 0.30901699  0.50000000  0.80901699  0.00000 
0.50000000  -0.80901699 0.30901699  0.00000 
44 'point symmetry operation' ?     ?     0.80901699  -0.30901699 -0.50000000 0.00000 0.30901699  -0.50000000 0.80901699  0.00000 
-0.50000000 -0.80901699 -0.30901699 0.00000 
45 'point symmetry operation' ?     ?     0.30901699  -0.50000000 -0.80901699 0.00000 -0.50000000 -0.80901699 0.30901699  0.00000 
-0.80901699 0.30901699  -0.50000000 0.00000 
46 'point symmetry operation' ?     ?     0.00000000  0.00000000  -1.00000000 0.00000 1.00000000  0.00000000  0.00000000  0.00000 
0.00000000  -1.00000000 0.00000000  0.00000 
47 'point symmetry operation' ?     ?     0.30901699  0.50000000  -0.80901699 0.00000 0.50000000  -0.80901699 -0.30901699 0.00000 
-0.80901699 -0.30901699 -0.50000000 0.00000 
48 'point symmetry operation' ?     ?     0.80901699  0.30901699  -0.50000000 0.00000 -0.30901699 -0.50000000 -0.80901699 0.00000 
-0.50000000 0.80901699  -0.30901699 0.00000 
49 'point symmetry operation' ?     ?     0.80901699  -0.30901699 -0.50000000 0.00000 -0.30901699 0.50000000  -0.80901699 0.00000 
0.50000000  0.80901699  0.30901699  0.00000 
50 'point symmetry operation' ?     ?     0.30901699  -0.50000000 -0.80901699 0.00000 0.50000000  0.80901699  -0.30901699 0.00000 
0.80901699  -0.30901699 0.50000000  0.00000 
51 'point symmetry operation' ?     ?     0.00000000  0.00000000  1.00000000  0.00000 -1.00000000 0.00000000  0.00000000  0.00000 
0.00000000  -1.00000000 0.00000000  0.00000 
52 'point symmetry operation' ?     ?     -0.30901699 -0.50000000 0.80901699  0.00000 -0.50000000 0.80901699  0.30901699  0.00000 
-0.80901699 -0.30901699 -0.50000000 0.00000 
53 'point symmetry operation' ?     ?     -0.80901699 -0.30901699 0.50000000  0.00000 0.30901699  0.50000000  0.80901699  0.00000 
-0.50000000 0.80901699  -0.30901699 0.00000 
54 'point symmetry operation' ?     ?     -0.80901699 0.30901699  0.50000000  0.00000 0.30901699  -0.50000000 0.80901699  0.00000 
0.50000000  0.80901699  0.30901699  0.00000 
55 'point symmetry operation' ?     ?     -0.30901699 0.50000000  0.80901699  0.00000 -0.50000000 -0.80901699 0.30901699  0.00000 
0.80901699  -0.30901699 0.50000000  0.00000 
56 'point symmetry operation' ?     ?     0.00000000  0.00000000  1.00000000  0.00000 1.00000000  0.00000000  0.00000000  0.00000 
0.00000000  1.00000000  0.00000000  0.00000 
57 'point symmetry operation' ?     ?     -0.30901699 -0.50000000 0.80901699  0.00000 0.50000000  -0.80901699 -0.30901699 0.00000 
0.80901699  0.30901699  0.50000000  0.00000 
58 'point symmetry operation' ?     ?     -0.80901699 -0.30901699 0.50000000  0.00000 -0.30901699 -0.50000000 -0.80901699 0.00000 
0.50000000  -0.80901699 0.30901699  0.00000 
59 'point symmetry operation' ?     ?     -0.80901699 0.30901699  0.50000000  0.00000 -0.30901699 0.50000000  -0.80901699 0.00000 
-0.50000000 -0.80901699 -0.30901699 0.00000 
60 'point symmetry operation' ?     ?     -0.30901699 0.50000000  0.80901699  0.00000 0.50000000  0.80901699  -0.30901699 0.00000 
-0.80901699 0.30901699  -0.50000000 0.00000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 TYR A 6   ? GLY A 10  ? TYR A 6   GLY A 10  5 ? 5  
HELX_P HELX_P2  AA2 THR A 12  ? PHE A 18  ? THR A 12  PHE A 18  1 ? 7  
HELX_P HELX_P3  AA3 LEU A 19  ? PHE A 24  ? LEU A 19  PHE A 24  5 ? 6  
HELX_P HELX_P4  AA4 SER A 26  ? SER A 44  ? SER A 26  SER A 44  1 ? 19 
HELX_P HELX_P5  AA5 SER A 49  ? LEU A 76  ? SER A 49  LEU A 76  1 ? 28 
HELX_P HELX_P6  AA6 ASP A 78  ? THR A 91  ? ASP A 78  THR A 91  1 ? 14 
HELX_P HELX_P7  AA7 THR A 91  ? GLY A 111 ? THR A 91  GLY A 111 1 ? 21 
HELX_P HELX_P8  AA8 GLY A 111 ? THR A 128 ? GLY A 111 THR A 128 1 ? 18 
HELX_P HELX_P9  AA9 THR B 12  ? PHE B 18  ? THR B 12  PHE B 18  1 ? 7  
HELX_P HELX_P10 AB1 SER B 26  ? GLU B 43  ? SER B 26  GLU B 43  1 ? 18 
HELX_P HELX_P11 AB2 SER B 49  ? LEU B 76  ? SER B 49  LEU B 76  1 ? 28 
HELX_P HELX_P12 AB3 ASP B 78  ? PHE B 110 ? ASP B 78  PHE B 110 1 ? 33 
HELX_P HELX_P13 AB4 GLY B 111 ? THR B 128 ? GLY B 111 THR B 128 1 ? 18 
HELX_P HELX_P14 AB5 TYR C 6   ? GLY C 10  ? TYR C 6   GLY C 10  5 ? 5  
HELX_P HELX_P15 AB6 THR C 12  ? LEU C 19  ? THR C 12  LEU C 19  1 ? 8  
HELX_P HELX_P16 AB7 SER C 26  ? GLU C 43  ? SER C 26  GLU C 43  1 ? 18 
HELX_P HELX_P17 AB8 SER C 49  ? LEU C 76  ? SER C 49  LEU C 76  1 ? 28 
HELX_P HELX_P18 AB9 ASP C 78  ? GLY C 111 ? ASP C 78  GLY C 111 1 ? 34 
HELX_P HELX_P19 AC1 GLY C 111 ? THR C 128 ? GLY C 111 THR C 128 1 ? 18 
HELX_P HELX_P20 AC2 PRO C 129 ? ARG C 133 ? PRO C 129 ARG C 133 5 ? 5  
HELX_P HELX_P21 AC3 TYR D 6   ? GLY D 10  ? TYR D 6   GLY D 10  5 ? 5  
HELX_P HELX_P22 AC4 THR D 12  ? PHE D 18  ? THR D 12  PHE D 18  1 ? 7  
HELX_P HELX_P23 AC5 SER D 26  ? GLU D 43  ? SER D 26  GLU D 43  1 ? 18 
HELX_P HELX_P24 AC6 SER D 49  ? ASN D 75  ? SER D 49  ASN D 75  1 ? 27 
HELX_P HELX_P25 AC7 ASP D 78  ? PHE D 110 ? ASP D 78  PHE D 110 1 ? 33 
HELX_P HELX_P26 AC8 GLY D 111 ? THR D 128 ? GLY D 111 THR D 128 1 ? 18 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ? ? A CYS 61 SG ? ? ? 1_555 B CYS 61 SG ? ? A CYS 61 B CYS 61 1_555 ? ? ? ? ? ? ? 1.949 ? ? 
disulf2 disulf ? ? C CYS 61 SG ? ? ? 1_555 D CYS 61 SG ? ? C CYS 61 D CYS 61 1_555 ? ? ? ? ? ? ? 2.078 ? ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 CYS A 61 ? CYS B 61 ? CYS A 61 ? 1_555 CYS B 61 ? 1_555 SG SG . . . None 'Disulfide bridge' 
2 CYS C 61 ? CYS D 61 ? CYS C 61 ? 1_555 CYS D 61 ? 1_555 SG SG . . . None 'Disulfide bridge' 
# 
_struct_sheet.id               AA1 
_struct_sheet.type             ? 
_struct_sheet.number_strands   2 
_struct_sheet.details          ? 
# 
_struct_sheet_order.sheet_id     AA1 
_struct_sheet_order.range_id_1   1 
_struct_sheet_order.range_id_2   2 
_struct_sheet_order.offset       ? 
_struct_sheet_order.sense        parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 THR B 147 ? VAL B 148 ? THR B 147 VAL B 148 
AA1 2 ILE C 139 ? LEU C 140 ? ILE C 139 LEU C 140 
# 
_pdbx_struct_sheet_hbond.sheet_id                AA1 
_pdbx_struct_sheet_hbond.range_id_1              1 
_pdbx_struct_sheet_hbond.range_id_2              2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id   N 
_pdbx_struct_sheet_hbond.range_1_label_comp_id   VAL 
_pdbx_struct_sheet_hbond.range_1_label_asym_id   B 
_pdbx_struct_sheet_hbond.range_1_label_seq_id    148 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code    ? 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id    N 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id    VAL 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id    B 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id     148 
_pdbx_struct_sheet_hbond.range_2_label_atom_id   O 
_pdbx_struct_sheet_hbond.range_2_label_comp_id   ILE 
_pdbx_struct_sheet_hbond.range_2_label_asym_id   C 
_pdbx_struct_sheet_hbond.range_2_label_seq_id    139 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code    ? 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id    O 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id    ILE 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id    C 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id     139 
# 
_pdbx_entry_details.entry_id                   8UYT 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_ligand_of_interest     ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 ASN B 75  ? ? -97.59  -64.85 
2 1 THR B 91  ? ? -93.67  -69.61 
3 1 GLU B 145 ? ? -152.67 29.00  
4 1 THR C 91  ? ? -98.78  -69.17 
5 1 THR D 91  ? ? -119.41 -70.49 
# 
_pdbx_point_symmetry.entry_id             8UYT 
_pdbx_point_symmetry.Schoenflies_symbol   I 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8UYT 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         REAL 
_em_3d_fitting.ref_protocol      'FLEXIBLE FIT' 
# 
_em_3d_fitting_list.id                            1 
_em_3d_fitting_list.3d_fitting_id                 1 
_em_3d_fitting_list.pdb_entry_id                  1QGT 
_em_3d_fitting_list.pdb_chain_id                  ? 
_em_3d_fitting_list.pdb_chain_residue_range       ? 
_em_3d_fitting_list.details                       ? 
_em_3d_fitting_list.chain_id                      ? 
_em_3d_fitting_list.chain_residue_range           ? 
_em_3d_fitting_list.source_name                   PDB 
_em_3d_fitting_list.type                          'experimental model' 
_em_3d_fitting_list.accession_code                1QGT 
_em_3d_fitting_list.initial_refinement_model_id   1 
# 
_em_3d_reconstruction.entry_id                    8UYT 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  2.7 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               35089 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       '30mM NaCl, 50mM Tris-HCl(pH7.5), 2mM DTT' 
_em_buffer.pH            7.5 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 VIRUS 
_em_entity_assembly.name                 'Hepatitis B virus' 
_em_entity_assembly.details              
'Recombinant HBV capsid protein was expressed by transfecting HEK-293T cells with a plasmid containing HBV capsid protein gene.' 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_imaging.entry_id                        8UYT 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           'FEI TITAN KRIOS AUTOGRID HOLDER' 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      2.7 
_em_imaging.nominal_defocus_min             500 
_em_imaging.nominal_defocus_max             3000 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           10500 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             BASIC 
_em_imaging.c2_aperture_diameter            50 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         NITROGEN 
# 
_em_sample_support.id               1 
_em_sample_support.film_material    ? 
_em_sample_support.method           ? 
_em_sample_support.grid_material    COPPER 
_em_sample_support.grid_mesh_size   300 
_em_sample_support.grid_type        'EMS Lacey Carbon' 
_em_sample_support.details          ? 
_em_sample_support.specimen_id      1 
_em_sample_support.citation_id      ? 
# 
_em_virus_entity.id                    1 
_em_virus_entity.virus_host_category   ? 
_em_virus_entity.virus_type            'VIRUS-LIKE PARTICLE' 
_em_virus_entity.virus_isolate         OTHER 
_em_virus_entity.entity_assembly_id    1 
_em_virus_entity.enveloped             NO 
_em_virus_entity.empty                 YES 
_em_virus_entity.details               ? 
# 
_em_vitrification.entry_id              8UYT 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              100 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   277 
_em_vitrification.instrument            'FEI VITROBOT MARK IV' 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                8UYT 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
_em_single_particle_entity.entry_id              8UYT 
_em_single_particle_entity.id                    1 
_em_single_particle_entity.image_processing_id   1 
_em_single_particle_entity.point_symmetry        I 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A GLU 145 ? A GLU 145 
2  1 Y 1 A THR 146 ? A THR 146 
3  1 Y 1 A THR 147 ? A THR 147 
4  1 Y 1 A VAL 148 ? A VAL 148 
5  1 Y 1 A VAL 149 ? A VAL 149 
6  1 Y 1 A ARG 150 ? A ARG 150 
7  1 Y 1 A ARG 151 ? A ARG 151 
8  1 Y 1 A ARG 152 ? A ARG 152 
9  1 Y 1 A GLY 153 ? A GLY 153 
10 1 Y 1 C THR 147 ? C THR 147 
11 1 Y 1 C VAL 148 ? C VAL 148 
12 1 Y 1 C VAL 149 ? C VAL 149 
13 1 Y 1 C ARG 150 ? C ARG 150 
14 1 Y 1 C ARG 151 ? C ARG 151 
15 1 Y 1 C ARG 152 ? C ARG 152 
16 1 Y 1 C GLY 153 ? C GLY 153 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
PHE N    N N N 247 
PHE CA   C N S 248 
PHE C    C N N 249 
PHE O    O N N 250 
PHE CB   C N N 251 
PHE CG   C Y N 252 
PHE CD1  C Y N 253 
PHE CD2  C Y N 254 
PHE CE1  C Y N 255 
PHE CE2  C Y N 256 
PHE CZ   C Y N 257 
PHE OXT  O N N 258 
PHE H    H N N 259 
PHE H2   H N N 260 
PHE HA   H N N 261 
PHE HB2  H N N 262 
PHE HB3  H N N 263 
PHE HD1  H N N 264 
PHE HD2  H N N 265 
PHE HE1  H N N 266 
PHE HE2  H N N 267 
PHE HZ   H N N 268 
PHE HXT  H N N 269 
PRO N    N N N 270 
PRO CA   C N S 271 
PRO C    C N N 272 
PRO O    O N N 273 
PRO CB   C N N 274 
PRO CG   C N N 275 
PRO CD   C N N 276 
PRO OXT  O N N 277 
PRO H    H N N 278 
PRO HA   H N N 279 
PRO HB2  H N N 280 
PRO HB3  H N N 281 
PRO HG2  H N N 282 
PRO HG3  H N N 283 
PRO HD2  H N N 284 
PRO HD3  H N N 285 
PRO HXT  H N N 286 
SER N    N N N 287 
SER CA   C N S 288 
SER C    C N N 289 
SER O    O N N 290 
SER CB   C N N 291 
SER OG   O N N 292 
SER OXT  O N N 293 
SER H    H N N 294 
SER H2   H N N 295 
SER HA   H N N 296 
SER HB2  H N N 297 
SER HB3  H N N 298 
SER HG   H N N 299 
SER HXT  H N N 300 
THR N    N N N 301 
THR CA   C N S 302 
THR C    C N N 303 
THR O    O N N 304 
THR CB   C N R 305 
THR OG1  O N N 306 
THR CG2  C N N 307 
THR OXT  O N N 308 
THR H    H N N 309 
THR H2   H N N 310 
THR HA   H N N 311 
THR HB   H N N 312 
THR HG1  H N N 313 
THR HG21 H N N 314 
THR HG22 H N N 315 
THR HG23 H N N 316 
THR HXT  H N N 317 
TRP N    N N N 318 
TRP CA   C N S 319 
TRP C    C N N 320 
TRP O    O N N 321 
TRP CB   C N N 322 
TRP CG   C Y N 323 
TRP CD1  C Y N 324 
TRP CD2  C Y N 325 
TRP NE1  N Y N 326 
TRP CE2  C Y N 327 
TRP CE3  C Y N 328 
TRP CZ2  C Y N 329 
TRP CZ3  C Y N 330 
TRP CH2  C Y N 331 
TRP OXT  O N N 332 
TRP H    H N N 333 
TRP H2   H N N 334 
TRP HA   H N N 335 
TRP HB2  H N N 336 
TRP HB3  H N N 337 
TRP HD1  H N N 338 
TRP HE1  H N N 339 
TRP HE3  H N N 340 
TRP HZ2  H N N 341 
TRP HZ3  H N N 342 
TRP HH2  H N N 343 
TRP HXT  H N N 344 
TYR N    N N N 345 
TYR CA   C N S 346 
TYR C    C N N 347 
TYR O    O N N 348 
TYR CB   C N N 349 
TYR CG   C Y N 350 
TYR CD1  C Y N 351 
TYR CD2  C Y N 352 
TYR CE1  C Y N 353 
TYR CE2  C Y N 354 
TYR CZ   C Y N 355 
TYR OH   O N N 356 
TYR OXT  O N N 357 
TYR H    H N N 358 
TYR H2   H N N 359 
TYR HA   H N N 360 
TYR HB2  H N N 361 
TYR HB3  H N N 362 
TYR HD1  H N N 363 
TYR HD2  H N N 364 
TYR HE1  H N N 365 
TYR HE2  H N N 366 
TYR HH   H N N 367 
TYR HXT  H N N 368 
VAL N    N N N 369 
VAL CA   C N S 370 
VAL C    C N N 371 
VAL O    O N N 372 
VAL CB   C N N 373 
VAL CG1  C N N 374 
VAL CG2  C N N 375 
VAL OXT  O N N 376 
VAL H    H N N 377 
VAL H2   H N N 378 
VAL HA   H N N 379 
VAL HB   H N N 380 
VAL HG11 H N N 381 
VAL HG12 H N N 382 
VAL HG13 H N N 383 
VAL HG21 H N N 384 
VAL HG22 H N N 385 
VAL HG23 H N N 386 
VAL HXT  H N N 387 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SER N   CA   sing N N 275 
SER N   H    sing N N 276 
SER N   H2   sing N N 277 
SER CA  C    sing N N 278 
SER CA  CB   sing N N 279 
SER CA  HA   sing N N 280 
SER C   O    doub N N 281 
SER C   OXT  sing N N 282 
SER CB  OG   sing N N 283 
SER CB  HB2  sing N N 284 
SER CB  HB3  sing N N 285 
SER OG  HG   sing N N 286 
SER OXT HXT  sing N N 287 
THR N   CA   sing N N 288 
THR N   H    sing N N 289 
THR N   H2   sing N N 290 
THR CA  C    sing N N 291 
THR CA  CB   sing N N 292 
THR CA  HA   sing N N 293 
THR C   O    doub N N 294 
THR C   OXT  sing N N 295 
THR CB  OG1  sing N N 296 
THR CB  CG2  sing N N 297 
THR CB  HB   sing N N 298 
THR OG1 HG1  sing N N 299 
THR CG2 HG21 sing N N 300 
THR CG2 HG22 sing N N 301 
THR CG2 HG23 sing N N 302 
THR OXT HXT  sing N N 303 
TRP N   CA   sing N N 304 
TRP N   H    sing N N 305 
TRP N   H2   sing N N 306 
TRP CA  C    sing N N 307 
TRP CA  CB   sing N N 308 
TRP CA  HA   sing N N 309 
TRP C   O    doub N N 310 
TRP C   OXT  sing N N 311 
TRP CB  CG   sing N N 312 
TRP CB  HB2  sing N N 313 
TRP CB  HB3  sing N N 314 
TRP CG  CD1  doub Y N 315 
TRP CG  CD2  sing Y N 316 
TRP CD1 NE1  sing Y N 317 
TRP CD1 HD1  sing N N 318 
TRP CD2 CE2  doub Y N 319 
TRP CD2 CE3  sing Y N 320 
TRP NE1 CE2  sing Y N 321 
TRP NE1 HE1  sing N N 322 
TRP CE2 CZ2  sing Y N 323 
TRP CE3 CZ3  doub Y N 324 
TRP CE3 HE3  sing N N 325 
TRP CZ2 CH2  doub Y N 326 
TRP CZ2 HZ2  sing N N 327 
TRP CZ3 CH2  sing Y N 328 
TRP CZ3 HZ3  sing N N 329 
TRP CH2 HH2  sing N N 330 
TRP OXT HXT  sing N N 331 
TYR N   CA   sing N N 332 
TYR N   H    sing N N 333 
TYR N   H2   sing N N 334 
TYR CA  C    sing N N 335 
TYR CA  CB   sing N N 336 
TYR CA  HA   sing N N 337 
TYR C   O    doub N N 338 
TYR C   OXT  sing N N 339 
TYR CB  CG   sing N N 340 
TYR CB  HB2  sing N N 341 
TYR CB  HB3  sing N N 342 
TYR CG  CD1  doub Y N 343 
TYR CG  CD2  sing Y N 344 
TYR CD1 CE1  sing Y N 345 
TYR CD1 HD1  sing N N 346 
TYR CD2 CE2  doub Y N 347 
TYR CD2 HD2  sing N N 348 
TYR CE1 CZ   doub Y N 349 
TYR CE1 HE1  sing N N 350 
TYR CE2 CZ   sing Y N 351 
TYR CE2 HE2  sing N N 352 
TYR CZ  OH   sing N N 353 
TYR OH  HH   sing N N 354 
TYR OXT HXT  sing N N 355 
VAL N   CA   sing N N 356 
VAL N   H    sing N N 357 
VAL N   H2   sing N N 358 
VAL CA  C    sing N N 359 
VAL CA  CB   sing N N 360 
VAL CA  HA   sing N N 361 
VAL C   O    doub N N 362 
VAL C   OXT  sing N N 363 
VAL CB  CG1  sing N N 364 
VAL CB  CG2  sing N N 365 
VAL CB  HB   sing N N 366 
VAL CG1 HG11 sing N N 367 
VAL CG1 HG12 sing N N 368 
VAL CG1 HG13 sing N N 369 
VAL CG2 HG21 sing N N 370 
VAL CG2 HG22 sing N N 371 
VAL CG2 HG23 sing N N 372 
VAL OXT HXT  sing N N 373 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2023-11-14 
_em_admin.deposition_site    RCSB 
_em_admin.entry_id           8UYT 
_em_admin.last_update        2024-11-20 
_em_admin.map_release_date   2024-11-20 
_em_admin.title              'HBV T=4 capsid from HEK-293T cells' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING ONLY' 
# 
_em_entity_assembly_molwt.entity_assembly_id   1 
_em_entity_assembly_molwt.experimental_flag    NO 
_em_entity_assembly_molwt.id                   1 
_em_entity_assembly_molwt.units                MEGADALTONS 
_em_entity_assembly_molwt.value                5 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          10407 
_em_entity_assembly_naturalsource.organism             'Hepatitis B virus' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 HEK-293T 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          9606 
_em_entity_assembly_recombinant.organism             'Homo sapiens' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         30 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 BIOQUANTUM (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
_em_imaging_optics.chr_aberration_corrector   ? 
_em_imaging_optics.energyfilter_lower         ? 
_em_imaging_optics.energyfilter_slit_width    30 
_em_imaging_optics.energyfilter_name          'GIF Bioquantum' 
_em_imaging_optics.energyfilter_upper         ? 
_em_imaging_optics.id                         1 
_em_imaging_optics.imaging_id                 1 
_em_imaging_optics.phase_plate                ? 
_em_imaging_optics.sph_aberration_corrector   ? 
_em_imaging_optics.details                    ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'            ? 1  ? ? ? ?               ? 
'IMAGE ACQUISITION'             ? 2  ? ? 1 EPU             ? 
MASKING                         ? 3  ? ? ? ?               ? 
'CTF CORRECTION'                ? 4  ? ? ? ?               ? 
'LAYERLINE INDEXING'            ? 5  ? ? ? ?               ? 
'DIFFRACTION INDEXING'          ? 6  ? ? ? ?               ? 
'MODEL FITTING'                 ? 7  ? 1 ? 'UCSF ChimeraX' ? 
OTHER                           ? 8  ? ? ? ?               ? 
'INITIAL EULER ASSIGNMENT'      ? 9  ? ? ? ?               ? 
'FINAL EULER ASSIGNMENT'        ? 10 ? ? ? ?               ? 
CLASSIFICATION                  ? 11 ? ? ? ?               ? 
RECONSTRUCTION                  ? 12 ? ? ? ?               ? 
'MODEL REFINEMENT'              ? 13 ? 1 ? ISOLDE          ? 
'MODEL REFINEMENT'              ? 14 ? 1 ? PHENIX          ? 
'MODEL REFINEMENT'              ? 15 ? 1 ? Coot            ? 
'VOLUME SELECTION'              ? 16 1 1 1 ?               ? 
'SERIES ALIGNMENT'              ? 17 1 1 1 ?               ? 
'MOLECULAR REPLACEMENT'         ? 18 1 1 1 ?               ? 
'LATTICE DISTORTION CORRECTION' ? 19 1 1 1 ?               ? 
'SYMMETRY DETERMINATION'        ? 20 1 1 1 ?               ? 
'CRYSTALLOGRAPHY MERGING'       ? 21 1 1 1 ?               ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 'Sample was monodisperse.' 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_em_virus_natural_host.entity_assembly_id   1 
_em_virus_natural_host.id                   1 
_em_virus_natural_host.ncbi_tax_id          9606 
_em_virus_natural_host.organism             'Homo sapiens' 
_em_virus_natural_host.strain               ? 
# 
_em_virus_shell.diameter             340 
_em_virus_shell.entity_assembly_id   1 
_em_virus_shell.id                   1 
_em_virus_shell.name                 'capsid protein' 
_em_virus_shell.triangulation        4 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID)' 'United States' AI173104 1 
'National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID)' 'United States' AI043453 2 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   1QGT 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    8UYT 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM 1    N N   . MET A 1 1   ? -37.405 14.350  143.793 1.00 19.75  ? 1   MET A N   1 
ATOM 2    C CA  . MET A 1 1   ? -36.904 14.200  142.398 1.00 19.75  ? 1   MET A CA  1 
ATOM 3    C C   . MET A 1 1   ? -38.048 14.409  141.404 1.00 19.75  ? 1   MET A C   1 
ATOM 4    O O   . MET A 1 1   ? -37.841 14.381  140.193 1.00 19.75  ? 1   MET A O   1 
ATOM 5    C CB  . MET A 1 1   ? -36.259 12.826  142.207 1.00 19.75  ? 1   MET A CB  1 
ATOM 6    C CG  . MET A 1 1   ? -35.560 12.643  140.868 1.00 19.75  ? 1   MET A CG  1 
ATOM 7    S SD  . MET A 1 1   ? -34.692 11.069  140.754 1.00 19.75  ? 1   MET A SD  1 
ATOM 8    C CE  . MET A 1 1   ? -33.325 11.373  141.864 1.00 19.75  ? 1   MET A CE  1 
ATOM 9    N N   . ASP A 1 2   ? -39.254 14.627  141.930 1.00 20.20  ? 2   ASP A N   1 
ATOM 10   C CA  . ASP A 1 2   ? -40.423 14.952  141.112 1.00 20.20  ? 2   ASP A CA  1 
ATOM 11   C C   . ASP A 1 2   ? -40.645 13.930  140.002 1.00 20.20  ? 2   ASP A C   1 
ATOM 12   O O   . ASP A 1 2   ? -40.942 14.279  138.859 1.00 20.20  ? 2   ASP A O   1 
ATOM 13   C CB  . ASP A 1 2   ? -40.292 16.357  140.525 1.00 20.20  ? 2   ASP A CB  1 
ATOM 14   C CG  . ASP A 1 2   ? -41.630 16.949  140.128 1.00 20.20  ? 2   ASP A CG  1 
ATOM 15   O OD1 . ASP A 1 2   ? -42.667 16.483  140.645 1.00 20.20  ? 2   ASP A OD1 1 
ATOM 16   O OD2 . ASP A 1 2   ? -41.644 17.879  139.296 1.00 20.20  ? 2   ASP A OD2 1 
ATOM 17   N N   . ILE A 1 3   ? -40.503 12.651  140.337 1.00 15.64  ? 3   ILE A N   1 
ATOM 18   C CA  . ILE A 1 3   ? -40.790 11.585  139.385 1.00 15.64  ? 3   ILE A CA  1 
ATOM 19   C C   . ILE A 1 3   ? -42.294 11.355  139.348 1.00 15.64  ? 3   ILE A C   1 
ATOM 20   O O   . ILE A 1 3   ? -42.948 11.270  140.394 1.00 15.64  ? 3   ILE A O   1 
ATOM 21   C CB  . ILE A 1 3   ? -40.045 10.295  139.769 1.00 15.64  ? 3   ILE A CB  1 
ATOM 22   C CG1 . ILE A 1 3   ? -38.540 10.546  139.832 1.00 15.64  ? 3   ILE A CG1 1 
ATOM 23   C CG2 . ILE A 1 3   ? -40.333 9.167   138.768 1.00 15.64  ? 3   ILE A CG2 1 
ATOM 24   C CD1 . ILE A 1 3   ? -37.729 9.273   139.944 1.00 15.64  ? 3   ILE A CD1 1 
ATOM 25   N N   . ASP A 1 4   ? -42.845 11.249  138.142 1.00 14.54  ? 4   ASP A N   1 
ATOM 26   C CA  . ASP A 1 4   ? -44.255 10.961  137.955 1.00 14.54  ? 4   ASP A CA  1 
ATOM 27   C C   . ASP A 1 4   ? -44.393 9.533   137.454 1.00 14.54  ? 4   ASP A C   1 
ATOM 28   O O   . ASP A 1 4   ? -43.747 9.180   136.458 1.00 14.54  ? 4   ASP A O   1 
ATOM 29   C CB  . ASP A 1 4   ? -44.882 11.935  136.954 1.00 14.54  ? 4   ASP A CB  1 
ATOM 30   C CG  . ASP A 1 4   ? -46.385 11.754  136.820 1.00 14.54  ? 4   ASP A CG  1 
ATOM 31   O OD1 . ASP A 1 4   ? -46.825 10.673  136.376 1.00 14.54  ? 4   ASP A OD1 1 
ATOM 32   O OD2 . ASP A 1 4   ? -47.128 12.698  137.158 1.00 14.54  ? 4   ASP A OD2 1 
ATOM 33   N N   . PRO A 1 5   ? -45.200 8.681   138.090 1.00 13.53  ? 5   PRO A N   1 
ATOM 34   C CA  . PRO A 1 5   ? -45.229 7.274   137.655 1.00 13.53  ? 5   PRO A CA  1 
ATOM 35   C C   . PRO A 1 5   ? -45.704 7.087   136.224 1.00 13.53  ? 5   PRO A C   1 
ATOM 36   O O   . PRO A 1 5   ? -45.182 6.219   135.514 1.00 13.53  ? 5   PRO A O   1 
ATOM 37   C CB  . PRO A 1 5   ? -46.192 6.615   138.654 1.00 13.53  ? 5   PRO A CB  1 
ATOM 38   C CG  . PRO A 1 5   ? -46.244 7.535   139.819 1.00 13.53  ? 5   PRO A CG  1 
ATOM 39   C CD  . PRO A 1 5   ? -46.047 8.908   139.273 1.00 13.53  ? 5   PRO A CD  1 
ATOM 40   N N   . TYR A 1 6   ? -46.680 7.875   135.778 1.00 12.26  ? 6   TYR A N   1 
ATOM 41   C CA  . TYR A 1 6   ? -47.311 7.672   134.482 1.00 12.26  ? 6   TYR A CA  1 
ATOM 42   C C   . TYR A 1 6   ? -46.807 8.614   133.395 1.00 12.26  ? 6   TYR A C   1 
ATOM 43   O O   . TYR A 1 6   ? -47.267 8.514   132.253 1.00 12.26  ? 6   TYR A O   1 
ATOM 44   C CB  . TYR A 1 6   ? -48.827 7.822   134.626 1.00 12.26  ? 6   TYR A CB  1 
ATOM 45   C CG  . TYR A 1 6   ? -49.367 7.193   135.889 1.00 12.26  ? 6   TYR A CG  1 
ATOM 46   C CD1 . TYR A 1 6   ? -49.602 5.827   135.965 1.00 12.26  ? 6   TYR A CD1 1 
ATOM 47   C CD2 . TYR A 1 6   ? -49.635 7.964   137.012 1.00 12.26  ? 6   TYR A CD2 1 
ATOM 48   C CE1 . TYR A 1 6   ? -50.091 5.248   137.120 1.00 12.26  ? 6   TYR A CE1 1 
ATOM 49   C CE2 . TYR A 1 6   ? -50.128 7.394   138.169 1.00 12.26  ? 6   TYR A CE2 1 
ATOM 50   C CZ  . TYR A 1 6   ? -50.352 6.035   138.219 1.00 12.26  ? 6   TYR A CZ  1 
ATOM 51   O OH  . TYR A 1 6   ? -50.841 5.463   139.371 1.00 12.26  ? 6   TYR A OH  1 
ATOM 52   N N   . LYS A 1 7   ? -45.883 9.526   133.709 1.00 14.54  ? 7   LYS A N   1 
ATOM 53   C CA  . LYS A 1 7   ? -45.475 10.517  132.716 1.00 14.54  ? 7   LYS A CA  1 
ATOM 54   C C   . LYS A 1 7   ? -44.853 9.857   131.491 1.00 14.54  ? 7   LYS A C   1 
ATOM 55   O O   . LYS A 1 7   ? -45.103 10.282  130.357 1.00 14.54  ? 7   LYS A O   1 
ATOM 56   C CB  . LYS A 1 7   ? -44.505 11.522  133.329 1.00 14.54  ? 7   LYS A CB  1 
ATOM 57   C CG  . LYS A 1 7   ? -44.144 12.661  132.393 1.00 14.54  ? 7   LYS A CG  1 
ATOM 58   C CD  . LYS A 1 7   ? -43.344 13.743  133.096 1.00 14.54  ? 7   LYS A CD  1 
ATOM 59   C CE  . LYS A 1 7   ? -42.501 14.528  132.112 1.00 14.54  ? 7   LYS A CE  1 
ATOM 60   N NZ  . LYS A 1 7   ? -42.433 15.966  132.467 1.00 14.54  ? 7   LYS A NZ  1 
ATOM 61   N N   . GLU A 1 8   ? -44.032 8.825   131.695 1.00 13.82  ? 8   GLU A N   1 
ATOM 62   C CA  . GLU A 1 8   ? -43.395 8.173   130.558 1.00 13.82  ? 8   GLU A CA  1 
ATOM 63   C C   . GLU A 1 8   ? -44.423 7.497   129.661 1.00 13.82  ? 8   GLU A C   1 
ATOM 64   O O   . GLU A 1 8   ? -44.203 7.376   128.451 1.00 13.82  ? 8   GLU A O   1 
ATOM 65   C CB  . GLU A 1 8   ? -42.339 7.176   131.041 1.00 13.82  ? 8   GLU A CB  1 
ATOM 66   C CG  . GLU A 1 8   ? -42.867 6.057   131.910 1.00 13.82  ? 8   GLU A CG  1 
ATOM 67   C CD  . GLU A 1 8   ? -41.771 5.108   132.354 1.00 13.82  ? 8   GLU A CD  1 
ATOM 68   O OE1 . GLU A 1 8   ? -40.982 4.664   131.493 1.00 13.82  ? 8   GLU A OE1 1 
ATOM 69   O OE2 . GLU A 1 8   ? -41.701 4.803   133.562 1.00 13.82  ? 8   GLU A OE2 1 
ATOM 70   N N   . PHE A 1 9   ? -45.542 7.052   130.229 1.00 12.13  ? 9   PHE A N   1 
ATOM 71   C CA  . PHE A 1 9   ? -46.569 6.335   129.487 1.00 12.13  ? 9   PHE A CA  1 
ATOM 72   C C   . PHE A 1 9   ? -47.625 7.270   128.912 1.00 12.13  ? 9   PHE A C   1 
ATOM 73   O O   . PHE A 1 9   ? -48.670 6.803   128.453 1.00 12.13  ? 9   PHE A O   1 
ATOM 74   C CB  . PHE A 1 9   ? -47.224 5.281   130.383 1.00 12.13  ? 9   PHE A CB  1 
ATOM 75   C CG  . PHE A 1 9   ? -46.247 4.324   131.000 1.00 12.13  ? 9   PHE A CG  1 
ATOM 76   C CD1 . PHE A 1 9   ? -45.730 3.272   130.263 1.00 12.13  ? 9   PHE A CD1 1 
ATOM 77   C CD2 . PHE A 1 9   ? -45.837 4.481   132.312 1.00 12.13  ? 9   PHE A CD2 1 
ATOM 78   C CE1 . PHE A 1 9   ? -44.826 2.394   130.825 1.00 12.13  ? 9   PHE A CE1 1 
ATOM 79   C CE2 . PHE A 1 9   ? -44.932 3.607   132.878 1.00 12.13  ? 9   PHE A CE2 1 
ATOM 80   C CZ  . PHE A 1 9   ? -44.429 2.560   132.135 1.00 12.13  ? 9   PHE A CZ  1 
ATOM 81   N N   . GLY A 1 10  ? -47.391 8.578   128.960 1.00 12.17  ? 10  GLY A N   1 
ATOM 82   C CA  . GLY A 1 10  ? -48.270 9.552   128.347 1.00 12.17  ? 10  GLY A CA  1 
ATOM 83   C C   . GLY A 1 10  ? -49.449 9.976   129.187 1.00 12.17  ? 10  GLY A C   1 
ATOM 84   O O   . GLY A 1 10  ? -50.365 10.616  128.661 1.00 12.17  ? 10  GLY A O   1 
ATOM 85   N N   . ALA A 1 11  ? -49.460 9.646   130.473 1.00 12.37  ? 11  ALA A N   1 
ATOM 86   C CA  . ALA A 1 11  ? -50.528 10.018  131.385 1.00 12.37  ? 11  ALA A CA  1 
ATOM 87   C C   . ALA A 1 11  ? -49.935 10.782  132.562 1.00 12.37  ? 11  ALA A C   1 
ATOM 88   O O   . ALA A 1 11  ? -48.719 10.811  132.764 1.00 12.37  ? 11  ALA A O   1 
ATOM 89   C CB  . ALA A 1 11  ? -51.294 8.783   131.876 1.00 12.37  ? 11  ALA A CB  1 
ATOM 90   N N   . THR A 1 12  ? -50.808 11.416  133.338 1.00 13.61  ? 12  THR A N   1 
ATOM 91   C CA  . THR A 1 12  ? -50.391 12.197  134.491 1.00 13.61  ? 12  THR A CA  1 
ATOM 92   C C   . THR A 1 12  ? -51.194 11.757  135.706 1.00 13.61  ? 12  THR A C   1 
ATOM 93   O O   . THR A 1 12  ? -52.249 11.126  135.584 1.00 13.61  ? 12  THR A O   1 
ATOM 94   C CB  . THR A 1 12  ? -50.571 13.705  134.258 1.00 13.61  ? 12  THR A CB  1 
ATOM 95   O OG1 . THR A 1 12  ? -51.953 13.994  134.004 1.00 13.61  ? 12  THR A OG1 1 
ATOM 96   C CG2 . THR A 1 12  ? -49.733 14.166  133.076 1.00 13.61  ? 12  THR A CG2 1 
ATOM 97   N N   . VAL A 1 13  ? -50.679 12.090  136.889 1.00 13.61  ? 13  VAL A N   1 
ATOM 98   C CA  . VAL A 1 13  ? -51.418 11.811  138.116 1.00 13.61  ? 13  VAL A CA  1 
ATOM 99   C C   . VAL A 1 13  ? -52.733 12.574  138.141 1.00 13.61  ? 13  VAL A C   1 
ATOM 100  O O   . VAL A 1 13  ? -53.742 12.077  138.653 1.00 13.61  ? 13  VAL A O   1 
ATOM 101  C CB  . VAL A 1 13  ? -50.543 12.146  139.342 1.00 13.61  ? 13  VAL A CB  1 
ATOM 102  C CG1 . VAL A 1 13  ? -51.356 12.076  140.627 1.00 13.61  ? 13  VAL A CG1 1 
ATOM 103  C CG2 . VAL A 1 13  ? -49.349 11.206  139.412 1.00 13.61  ? 13  VAL A CG2 1 
ATOM 104  N N   . GLU A 1 14  ? -52.747 13.793  137.594 1.00 15.57  ? 14  GLU A N   1 
ATOM 105  C CA  . GLU A 1 14  ? -53.987 14.554  137.493 1.00 15.57  ? 14  GLU A CA  1 
ATOM 106  C C   . GLU A 1 14  ? -55.026 13.838  136.636 1.00 15.57  ? 14  GLU A C   1 
ATOM 107  O O   . GLU A 1 14  ? -56.212 13.809  136.982 1.00 15.57  ? 14  GLU A O   1 
ATOM 108  C CB  . GLU A 1 14  ? -53.709 15.927  136.918 1.00 15.57  ? 14  GLU A CB  1 
ATOM 109  C CG  . GLU A 1 14  ? -52.915 16.750  137.906 1.00 15.57  ? 14  GLU A CG  1 
ATOM 110  C CD  . GLU A 1 14  ? -52.577 18.103  137.285 1.00 15.57  ? 14  GLU A CD  1 
ATOM 111  O OE1 . GLU A 1 14  ? -52.836 18.257  136.062 1.00 15.57  ? 14  GLU A OE1 1 
ATOM 112  O OE2 . GLU A 1 14  ? -52.062 18.970  138.041 1.00 15.57  ? 14  GLU A OE2 1 
ATOM 113  N N   . LEU A 1 15  ? -54.607 13.265  135.507 1.00 12.80  ? 15  LEU A N   1 
ATOM 114  C CA  . LEU A 1 15  ? -55.550 12.574  134.633 1.00 12.80  ? 15  LEU A CA  1 
ATOM 115  C C   . LEU A 1 15  ? -56.156 11.345  135.307 1.00 12.80  ? 15  LEU A C   1 
ATOM 116  O O   . LEU A 1 15  ? -57.357 11.087  135.177 1.00 12.80  ? 15  LEU A O   1 
ATOM 117  C CB  . LEU A 1 15  ? -54.856 12.183  133.329 1.00 12.80  ? 15  LEU A CB  1 
ATOM 118  C CG  . LEU A 1 15  ? -55.758 11.600  132.241 1.00 12.80  ? 15  LEU A CG  1 
ATOM 119  C CD1 . LEU A 1 15  ? -56.742 12.645  131.741 1.00 12.80  ? 15  LEU A CD1 1 
ATOM 120  C CD2 . LEU A 1 15  ? -54.919 11.072  131.096 1.00 12.80  ? 15  LEU A CD2 1 
ATOM 121  N N   . LEU A 1 16  ? -55.339 10.574  136.029 1.00 12.12  ? 16  LEU A N   1 
ATOM 122  C CA  . LEU A 1 16  ? -55.861 9.459   136.817 1.00 12.12  ? 16  LEU A CA  1 
ATOM 123  C C   . LEU A 1 16  ? -56.740 9.924   137.975 1.00 12.12  ? 16  LEU A C   1 
ATOM 124  O O   . LEU A 1 16  ? -57.657 9.202   138.379 1.00 12.12  ? 16  LEU A O   1 
ATOM 125  C CB  . LEU A 1 16  ? -54.710 8.600   137.337 1.00 12.12  ? 16  LEU A CB  1 
ATOM 126  C CG  . LEU A 1 16  ? -54.226 7.533   136.354 1.00 12.12  ? 16  LEU A CG  1 
ATOM 127  C CD1 . LEU A 1 16  ? -53.412 8.154   135.225 1.00 12.12  ? 16  LEU A CD1 1 
ATOM 128  C CD2 . LEU A 1 16  ? -53.429 6.467   137.076 1.00 12.12  ? 16  LEU A CD2 1 
ATOM 129  N N   . SER A 1 17  ? -56.470 11.107  138.526 1.00 13.53  ? 17  SER A N   1 
ATOM 130  C CA  . SER A 1 17  ? -57.319 11.659  139.578 1.00 13.53  ? 17  SER A CA  1 
ATOM 131  C C   . SER A 1 17  ? -58.784 11.725  139.164 1.00 13.53  ? 17  SER A C   1 
ATOM 132  O O   . SER A 1 17  ? -59.671 11.689  140.024 1.00 13.53  ? 17  SER A O   1 
ATOM 133  C CB  . SER A 1 17  ? -56.831 13.052  139.982 1.00 13.53  ? 17  SER A CB  1 
ATOM 134  O OG  . SER A 1 17  ? -55.547 12.999  140.574 1.00 13.53  ? 17  SER A OG  1 
ATOM 135  N N   . PHE A 1 18  ? -59.063 11.833  137.861 1.00 13.15  ? 18  PHE A N   1 
ATOM 136  C CA  . PHE A 1 18  ? -60.450 11.835  137.406 1.00 13.15  ? 18  PHE A CA  1 
ATOM 137  C C   . PHE A 1 18  ? -61.225 10.619  137.905 1.00 13.15  ? 18  PHE A C   1 
ATOM 138  O O   . PHE A 1 18  ? -62.384 10.748  138.317 1.00 13.15  ? 18  PHE A O   1 
ATOM 139  C CB  . PHE A 1 18  ? -60.508 11.878  135.876 1.00 13.15  ? 18  PHE A CB  1 
ATOM 140  C CG  . PHE A 1 18  ? -59.993 13.157  135.269 1.00 13.15  ? 18  PHE A CG  1 
ATOM 141  C CD1 . PHE A 1 18  ? -59.630 14.238  136.057 1.00 13.15  ? 18  PHE A CD1 1 
ATOM 142  C CD2 . PHE A 1 18  ? -59.898 13.283  133.892 1.00 13.15  ? 18  PHE A CD2 1 
ATOM 143  C CE1 . PHE A 1 18  ? -59.170 15.408  135.483 1.00 13.15  ? 18  PHE A CE1 1 
ATOM 144  C CE2 . PHE A 1 18  ? -59.436 14.448  133.315 1.00 13.15  ? 18  PHE A CE2 1 
ATOM 145  C CZ  . PHE A 1 18  ? -59.072 15.511  134.111 1.00 13.15  ? 18  PHE A CZ  1 
ATOM 146  N N   . LEU A 1 19  ? -60.623 9.433   137.880 1.00 11.13  ? 19  LEU A N   1 
ATOM 147  C CA  . LEU A 1 19  ? -61.324 8.278   138.426 1.00 11.13  ? 19  LEU A CA  1 
ATOM 148  C C   . LEU A 1 19  ? -61.418 8.383   139.948 1.00 11.13  ? 19  LEU A C   1 
ATOM 149  O O   . LEU A 1 19  ? -60.467 8.826   140.599 1.00 11.13  ? 19  LEU A O   1 
ATOM 150  C CB  . LEU A 1 19  ? -60.617 6.974   138.053 1.00 11.13  ? 19  LEU A CB  1 
ATOM 151  C CG  . LEU A 1 19  ? -60.218 6.749   136.596 1.00 11.13  ? 19  LEU A CG  1 
ATOM 152  C CD1 . LEU A 1 19  ? -59.162 5.660   136.512 1.00 11.13  ? 19  LEU A CD1 1 
ATOM 153  C CD2 . LEU A 1 19  ? -61.431 6.381   135.761 1.00 11.13  ? 19  LEU A CD2 1 
ATOM 154  N N   . PRO A 1 20  ? -62.540 7.980   140.546 1.00 11.74  ? 20  PRO A N   1 
ATOM 155  C CA  . PRO A 1 20  ? -62.624 7.961   142.010 1.00 11.74  ? 20  PRO A CA  1 
ATOM 156  C C   . PRO A 1 20  ? -61.776 6.843   142.597 1.00 11.74  ? 20  PRO A C   1 
ATOM 157  O O   . PRO A 1 20  ? -61.467 5.847   141.939 1.00 11.74  ? 20  PRO A O   1 
ATOM 158  C CB  . PRO A 1 20  ? -64.115 7.730   142.285 1.00 11.74  ? 20  PRO A CB  1 
ATOM 159  C CG  . PRO A 1 20  ? -64.806 8.021   140.998 1.00 11.74  ? 20  PRO A CG  1 
ATOM 160  C CD  . PRO A 1 20  ? -63.835 7.646   139.933 1.00 11.74  ? 20  PRO A CD  1 
ATOM 161  N N   . SER A 1 21  ? -61.392 7.021   143.862 1.00 12.79  ? 21  SER A N   1 
ATOM 162  C CA  . SER A 1 21  ? -60.560 6.011   144.510 1.00 12.79  ? 21  SER A CA  1 
ATOM 163  C C   . SER A 1 21  ? -61.293 4.676   144.599 1.00 12.79  ? 21  SER A C   1 
ATOM 164  O O   . SER A 1 21  ? -60.687 3.612   144.427 1.00 12.79  ? 21  SER A O   1 
ATOM 165  C CB  . SER A 1 21  ? -60.142 6.490   145.900 1.00 12.79  ? 21  SER A CB  1 
ATOM 166  O OG  . SER A 1 21  ? -59.351 7.662   145.817 1.00 12.79  ? 21  SER A OG  1 
ATOM 167  N N   . ASP A 1 22  ? -62.601 4.716   144.871 1.00 13.83  ? 22  ASP A N   1 
ATOM 168  C CA  . ASP A 1 22  ? -63.376 3.490   145.023 1.00 13.83  ? 22  ASP A CA  1 
ATOM 169  C C   . ASP A 1 22  ? -63.427 2.684   143.732 1.00 13.83  ? 22  ASP A C   1 
ATOM 170  O O   . ASP A 1 22  ? -63.608 1.462   143.769 1.00 13.83  ? 22  ASP A O   1 
ATOM 171  C CB  . ASP A 1 22  ? -64.796 3.828   145.480 1.00 13.83  ? 22  ASP A CB  1 
ATOM 172  C CG  . ASP A 1 22  ? -64.844 4.337   146.903 1.00 13.83  ? 22  ASP A CG  1 
ATOM 173  O OD1 . ASP A 1 22  ? -63.909 4.036   147.674 1.00 13.83  ? 22  ASP A OD1 1 
ATOM 174  O OD2 . ASP A 1 22  ? -65.822 5.029   147.258 1.00 13.83  ? 22  ASP A OD2 1 
ATOM 175  N N   . PHE A 1 23  ? -63.279 3.349   142.586 1.00 10.93  ? 23  PHE A N   1 
ATOM 176  C CA  . PHE A 1 23  ? -63.416 2.671   141.301 1.00 10.93  ? 23  PHE A CA  1 
ATOM 177  C C   . PHE A 1 23  ? -62.395 1.550   141.134 1.00 10.93  ? 23  PHE A C   1 
ATOM 178  O O   . PHE A 1 23  ? -62.717 0.486   140.596 1.00 10.93  ? 23  PHE A O   1 
ATOM 179  C CB  . PHE A 1 23  ? -63.275 3.692   140.170 1.00 10.93  ? 23  PHE A CB  1 
ATOM 180  C CG  . PHE A 1 23  ? -62.931 3.084   138.841 1.00 10.93  ? 23  PHE A CG  1 
ATOM 181  C CD1 . PHE A 1 23  ? -63.912 2.522   138.043 1.00 10.93  ? 23  PHE A CD1 1 
ATOM 182  C CD2 . PHE A 1 23  ? -61.625 3.090   138.381 1.00 10.93  ? 23  PHE A CD2 1 
ATOM 183  C CE1 . PHE A 1 23  ? -63.597 1.969   136.818 1.00 10.93  ? 23  PHE A CE1 1 
ATOM 184  C CE2 . PHE A 1 23  ? -61.304 2.540   137.157 1.00 10.93  ? 23  PHE A CE2 1 
ATOM 185  C CZ  . PHE A 1 23  ? -62.290 1.976   136.375 1.00 10.93  ? 23  PHE A CZ  1 
ATOM 186  N N   . PHE A 1 24  ? -61.166 1.768   141.584 1.00 11.16  ? 24  PHE A N   1 
ATOM 187  C CA  . PHE A 1 24  ? -60.108 0.801   141.341 1.00 11.16  ? 24  PHE A CA  1 
ATOM 188  C C   . PHE A 1 24  ? -60.433 -0.547  141.988 1.00 11.16  ? 24  PHE A C   1 
ATOM 189  O O   . PHE A 1 24  ? -60.918 -0.590  143.124 1.00 11.16  ? 24  PHE A O   1 
ATOM 190  C CB  . PHE A 1 24  ? -58.777 1.339   141.865 1.00 11.16  ? 24  PHE A CB  1 
ATOM 191  C CG  . PHE A 1 24  ? -58.339 2.602   141.188 1.00 11.16  ? 24  PHE A CG  1 
ATOM 192  C CD1 . PHE A 1 24  ? -57.758 2.562   139.932 1.00 11.16  ? 24  PHE A CD1 1 
ATOM 193  C CD2 . PHE A 1 24  ? -58.526 3.831   141.794 1.00 11.16  ? 24  PHE A CD2 1 
ATOM 194  C CE1 . PHE A 1 24  ? -57.364 3.721   139.299 1.00 11.16  ? 24  PHE A CE1 1 
ATOM 195  C CE2 . PHE A 1 24  ? -58.133 4.995   141.167 1.00 11.16  ? 24  PHE A CE2 1 
ATOM 196  C CZ  . PHE A 1 24  ? -57.551 4.940   139.917 1.00 11.16  ? 24  PHE A CZ  1 
ATOM 197  N N   . PRO A 1 25  ? -60.182 -1.661  141.299 1.00 11.50  ? 25  PRO A N   1 
ATOM 198  C CA  . PRO A 1 25  ? -60.497 -2.975  141.871 1.00 11.50  ? 25  PRO A CA  1 
ATOM 199  C C   . PRO A 1 25  ? -59.542 -3.361  142.989 1.00 11.50  ? 25  PRO A C   1 
ATOM 200  O O   . PRO A 1 25  ? -58.464 -2.787  143.163 1.00 11.50  ? 25  PRO A O   1 
ATOM 201  C CB  . PRO A 1 25  ? -60.364 -3.930  140.676 1.00 11.50  ? 25  PRO A CB  1 
ATOM 202  C CG  . PRO A 1 25  ? -60.383 -3.051  139.472 1.00 11.50  ? 25  PRO A CG  1 
ATOM 203  C CD  . PRO A 1 25  ? -59.708 -1.802  139.911 1.00 11.50  ? 25  PRO A CD  1 
ATOM 204  N N   . SER A 1 26  ? -59.962 -4.362  143.758 1.00 12.90  ? 26  SER A N   1 
ATOM 205  C CA  . SER A 1 26  ? -59.206 -4.809  144.919 1.00 12.90  ? 26  SER A CA  1 
ATOM 206  C C   . SER A 1 26  ? -57.874 -5.418  144.490 1.00 12.90  ? 26  SER A C   1 
ATOM 207  O O   . SER A 1 26  ? -57.718 -5.902  143.367 1.00 12.90  ? 26  SER A O   1 
ATOM 208  C CB  . SER A 1 26  ? -60.010 -5.833  145.718 1.00 12.90  ? 26  SER A CB  1 
ATOM 209  O OG  . SER A 1 26  ? -60.033 -7.087  145.062 1.00 12.90  ? 26  SER A OG  1 
ATOM 210  N N   . VAL A 1 27  ? -56.903 -5.385  145.406 1.00 13.53  ? 27  VAL A N   1 
ATOM 211  C CA  . VAL A 1 27  ? -55.557 -5.855  145.083 1.00 13.53  ? 27  VAL A CA  1 
ATOM 212  C C   . VAL A 1 27  ? -55.582 -7.323  144.683 1.00 13.53  ? 27  VAL A C   1 
ATOM 213  O O   . VAL A 1 27  ? -54.903 -7.732  143.732 1.00 13.53  ? 27  VAL A O   1 
ATOM 214  C CB  . VAL A 1 27  ? -54.609 -5.624  146.276 1.00 13.53  ? 27  VAL A CB  1 
ATOM 215  C CG1 . VAL A 1 27  ? -53.243 -6.226  145.988 1.00 13.53  ? 27  VAL A CG1 1 
ATOM 216  C CG2 . VAL A 1 27  ? -54.474 -4.148  146.577 1.00 13.53  ? 27  VAL A CG2 1 
ATOM 217  N N   . ARG A 1 28  ? -56.357 -8.143  145.397 1.00 15.45  ? 28  ARG A N   1 
ATOM 218  C CA  . ARG A 1 28  ? -56.346 -9.571  145.110 1.00 15.45  ? 28  ARG A CA  1 
ATOM 219  C C   . ARG A 1 28  ? -56.826 -9.832  143.688 1.00 15.45  ? 28  ARG A C   1 
ATOM 220  O O   . ARG A 1 28  ? -56.229 -10.630 142.955 1.00 15.45  ? 28  ARG A O   1 
ATOM 221  C CB  . ARG A 1 28  ? -57.225 -10.324 146.108 1.00 15.45  ? 28  ARG A CB  1 
ATOM 222  C CG  . ARG A 1 28  ? -57.106 -11.833 145.988 1.00 15.45  ? 28  ARG A CG  1 
ATOM 223  C CD  . ARG A 1 28  ? -55.696 -12.264 146.372 1.00 15.45  ? 28  ARG A CD  1 
ATOM 224  N NE  . ARG A 1 28  ? -54.865 -12.657 145.239 1.00 15.45  ? 28  ARG A NE  1 
ATOM 225  C CZ  . ARG A 1 28  ? -53.548 -12.791 145.298 1.00 15.45  ? 28  ARG A CZ  1 
ATOM 226  N NH1 . ARG A 1 28  ? -52.880 -12.566 146.418 1.00 15.45  ? 28  ARG A NH1 1 
ATOM 227  N NH2 . ARG A 1 28  ? -52.881 -13.150 144.204 1.00 15.45  ? 28  ARG A NH2 1 
ATOM 228  N N   . ASP A 1 29  ? -57.908 -9.159  143.280 1.00 14.54  ? 29  ASP A N   1 
ATOM 229  C CA  . ASP A 1 29  ? -58.471 -9.383  141.955 1.00 14.54  ? 29  ASP A CA  1 
ATOM 230  C C   . ASP A 1 29  ? -57.487 -8.960  140.872 1.00 14.54  ? 29  ASP A C   1 
ATOM 231  O O   . ASP A 1 29  ? -57.312 -9.660  139.867 1.00 14.54  ? 29  ASP A O   1 
ATOM 232  C CB  . ASP A 1 29  ? -59.791 -8.624  141.814 1.00 14.54  ? 29  ASP A CB  1 
ATOM 233  C CG  . ASP A 1 29  ? -60.944 -9.322  142.513 1.00 14.54  ? 29  ASP A CG  1 
ATOM 234  O OD1 . ASP A 1 29  ? -60.750 -10.450 143.011 1.00 14.54  ? 29  ASP A OD1 1 
ATOM 235  O OD2 . ASP A 1 29  ? -62.050 -8.745  142.554 1.00 14.54  ? 29  ASP A OD2 1 
ATOM 236  N N   . LEU A 1 30  ? -56.845 -7.805  141.057 1.00 12.64  ? 30  LEU A N   1 
ATOM 237  C CA  . LEU A 1 30  ? -55.908 -7.316  140.052 1.00 12.64  ? 30  LEU A CA  1 
ATOM 238  C C   . LEU A 1 30  ? -54.729 -8.268  139.933 1.00 12.64  ? 30  LEU A C   1 
ATOM 239  O O   . LEU A 1 30  ? -54.274 -8.575  138.823 1.00 12.64  ? 30  LEU A O   1 
ATOM 240  C CB  . LEU A 1 30  ? -55.435 -5.909  140.415 1.00 12.64  ? 30  LEU A CB  1 
ATOM 241  C CG  . LEU A 1 30  ? -56.403 -4.766  140.103 1.00 12.64  ? 30  LEU A CG  1 
ATOM 242  C CD1 . LEU A 1 30  ? -55.896 -3.477  140.718 1.00 12.64  ? 30  LEU A CD1 1 
ATOM 243  C CD2 . LEU A 1 30  ? -56.604 -4.600  138.604 1.00 12.64  ? 30  LEU A CD2 1 
ATOM 244  N N   . LEU A 1 31  ? -54.216 -8.745  141.070 1.00 13.88  ? 31  LEU A N   1 
ATOM 245  C CA  . LEU A 1 31  ? -53.090 -9.667  141.025 1.00 13.88  ? 31  LEU A CA  1 
ATOM 246  C C   . LEU A 1 31  ? -53.495 -10.965 140.341 1.00 13.88  ? 31  LEU A C   1 
ATOM 247  O O   . LEU A 1 31  ? -52.713 -11.543 139.579 1.00 13.88  ? 31  LEU A O   1 
ATOM 248  C CB  . LEU A 1 31  ? -52.565 -9.941  142.432 1.00 13.88  ? 31  LEU A CB  1 
ATOM 249  C CG  . LEU A 1 31  ? -51.670 -8.876  143.075 1.00 13.88  ? 31  LEU A CG  1 
ATOM 250  C CD1 . LEU A 1 31  ? -51.307 -9.290  144.489 1.00 13.88  ? 31  LEU A CD1 1 
ATOM 251  C CD2 . LEU A 1 31  ? -50.407 -8.620  142.260 1.00 13.88  ? 31  LEU A CD2 1 
ATOM 252  N N   . ASP A 1 32  ? -54.712 -11.451 140.614 1.00 15.39  ? 32  ASP A N   1 
ATOM 253  C CA  . ASP A 1 32  ? -55.160 -12.675 139.961 1.00 15.39  ? 32  ASP A CA  1 
ATOM 254  C C   . ASP A 1 32  ? -55.253 -12.476 138.453 1.00 15.39  ? 32  ASP A C   1 
ATOM 255  O O   . ASP A 1 32  ? -54.847 -13.351 137.680 1.00 15.39  ? 32  ASP A O   1 
ATOM 256  C CB  . ASP A 1 32  ? -56.511 -13.111 140.529 1.00 15.39  ? 32  ASP A CB  1 
ATOM 257  C CG  . ASP A 1 32  ? -56.403 -13.651 141.941 1.00 15.39  ? 32  ASP A CG  1 
ATOM 258  O OD1 . ASP A 1 32  ? -55.268 -13.905 142.398 1.00 15.39  ? 32  ASP A OD1 1 
ATOM 259  O OD2 . ASP A 1 32  ? -57.453 -13.823 142.596 1.00 15.39  ? 32  ASP A OD2 1 
ATOM 260  N N   . THR A 1 33  ? -55.776 -11.327 138.019 1.00 14.09  ? 33  THR A N   1 
ATOM 261  C CA  . THR A 1 33  ? -55.888 -11.072 136.585 1.00 14.09  ? 33  THR A CA  1 
ATOM 262  C C   . THR A 1 33  ? -54.508 -11.032 135.948 1.00 14.09  ? 33  THR A C   1 
ATOM 263  O O   . THR A 1 33  ? -54.280 -11.618 134.876 1.00 14.09  ? 33  THR A O   1 
ATOM 264  C CB  . THR A 1 33  ? -56.630 -9.758  136.337 1.00 14.09  ? 33  THR A CB  1 
ATOM 265  O OG1 . THR A 1 33  ? -57.893 -9.782  137.014 1.00 14.09  ? 33  THR A OG1 1 
ATOM 266  C CG2 . THR A 1 33  ? -56.864 -9.541  134.848 1.00 14.09  ? 33  THR A CG2 1 
ATOM 267  N N   . ALA A 1 34  ? -53.563 -10.368 136.619 1.00 14.09  ? 34  ALA A N   1 
ATOM 268  C CA  . ALA A 1 34  ? -52.215 -10.264 136.081 1.00 14.09  ? 34  ALA A CA  1 
ATOM 269  C C   . ALA A 1 34  ? -51.587 -11.640 135.982 1.00 14.09  ? 34  ALA A C   1 
ATOM 270  O O   . ALA A 1 34  ? -50.969 -11.978 134.971 1.00 14.09  ? 34  ALA A O   1 
ATOM 271  C CB  . ALA A 1 34  ? -51.361 -9.347  136.955 1.00 14.09  ? 34  ALA A CB  1 
ATOM 272  N N   . SER A 1 35  ? -51.752 -12.463 137.016 1.00 15.83  ? 35  SER A N   1 
ATOM 273  C CA  . SER A 1 35  ? -51.145 -13.784 136.983 1.00 15.83  ? 35  SER A CA  1 
ATOM 274  C C   . SER A 1 35  ? -51.740 -14.614 135.858 1.00 15.83  ? 35  SER A C   1 
ATOM 275  O O   . SER A 1 35  ? -51.002 -15.074 134.978 1.00 15.83  ? 35  SER A O   1 
ATOM 276  C CB  . SER A 1 35  ? -51.349 -14.483 138.324 1.00 15.83  ? 35  SER A CB  1 
ATOM 277  O OG  . SER A 1 35  ? -51.102 -15.868 138.206 1.00 15.83  ? 35  SER A OG  1 
ATOM 278  N N   . ALA A 1 36  ? -53.067 -14.550 135.717 1.00 14.78  ? 36  ALA A N   1 
ATOM 279  C CA  . ALA A 1 36  ? -53.785 -15.371 134.749 1.00 14.78  ? 36  ALA A CA  1 
ATOM 280  C C   . ALA A 1 36  ? -53.384 -15.024 133.328 1.00 14.78  ? 36  ALA A C   1 
ATOM 281  O O   . ALA A 1 36  ? -53.247 -15.919 132.486 1.00 14.78  ? 36  ALA A O   1 
ATOM 282  C CB  . ALA A 1 36  ? -55.292 -15.200 134.935 1.00 14.78  ? 36  ALA A CB  1 
ATOM 283  N N   . LEU A 1 37  ? -53.196 -13.744 133.031 1.00 14.76  ? 37  LEU A N   1 
ATOM 284  C CA  . LEU A 1 37  ? -52.950 -13.362 131.648 1.00 14.76  ? 37  LEU A CA  1 
ATOM 285  C C   . LEU A 1 37  ? -51.470 -13.201 131.331 1.00 14.76  ? 37  LEU A C   1 
ATOM 286  O O   . LEU A 1 37  ? -51.041 -13.593 130.242 1.00 14.76  ? 37  LEU A O   1 
ATOM 287  C CB  . LEU A 1 37  ? -53.681 -12.056 131.313 1.00 14.76  ? 37  LEU A CB  1 
ATOM 288  C CG  . LEU A 1 37  ? -55.199 -12.043 131.507 1.00 14.76  ? 37  LEU A CG  1 
ATOM 289  C CD1 . LEU A 1 37  ? -55.758 -10.653 131.247 1.00 14.76  ? 37  LEU A CD1 1 
ATOM 290  C CD2 . LEU A 1 37  ? -55.873 -13.066 130.603 1.00 14.76  ? 37  LEU A CD2 1 
ATOM 291  N N   . TYR A 1 38  ? -50.666 -12.635 132.235 1.00 14.44  ? 38  TYR A N   1 
ATOM 292  C CA  . TYR A 1 38  ? -49.282 -12.299 131.935 1.00 14.44  ? 38  TYR A CA  1 
ATOM 293  C C   . TYR A 1 38  ? -48.242 -13.006 132.811 1.00 14.44  ? 38  TYR A C   1 
ATOM 294  O O   . TYR A 1 38  ? -47.114 -12.513 132.889 1.00 14.44  ? 38  TYR A O   1 
ATOM 295  C CB  . TYR A 1 38  ? -49.103 -10.782 132.026 1.00 14.44  ? 38  TYR A CB  1 
ATOM 296  C CG  . TYR A 1 38  ? -50.142 -10.021 131.235 1.00 14.44  ? 38  TYR A CG  1 
ATOM 297  C CD1 . TYR A 1 38  ? -50.118 -10.022 129.847 1.00 14.44  ? 38  TYR A CD1 1 
ATOM 298  C CD2 . TYR A 1 38  ? -51.157 -9.319  131.871 1.00 14.44  ? 38  TYR A CD2 1 
ATOM 299  C CE1 . TYR A 1 38  ? -51.067 -9.338  129.115 1.00 14.44  ? 38  TYR A CE1 1 
ATOM 300  C CE2 . TYR A 1 38  ? -52.111 -8.631  131.146 1.00 14.44  ? 38  TYR A CE2 1 
ATOM 301  C CZ  . TYR A 1 38  ? -52.061 -8.646  129.769 1.00 14.44  ? 38  TYR A CZ  1 
ATOM 302  O OH  . TYR A 1 38  ? -53.006 -7.963  129.038 1.00 14.44  ? 38  TYR A OH  1 
ATOM 303  N N   . ARG A 1 39  ? -48.554 -14.111 133.513 1.00 17.26  ? 39  ARG A N   1 
ATOM 304  C CA  . ARG A 1 39  ? -47.529 -14.661 134.403 1.00 17.26  ? 39  ARG A CA  1 
ATOM 305  C C   . ARG A 1 39  ? -46.286 -15.068 133.618 1.00 17.26  ? 39  ARG A C   1 
ATOM 306  O O   . ARG A 1 39  ? -45.153 -14.736 134.002 1.00 17.26  ? 39  ARG A O   1 
ATOM 307  C CB  . ARG A 1 39  ? -48.075 -15.873 135.164 1.00 17.26  ? 39  ARG A CB  1 
ATOM 308  C CG  . ARG A 1 39  ? -47.078 -16.504 136.141 1.00 17.26  ? 39  ARG A CG  1 
ATOM 309  C CD  . ARG A 1 39  ? -47.689 -17.663 136.931 1.00 17.26  ? 39  ARG A CD  1 
ATOM 310  N NE  . ARG A 1 39  ? -46.787 -18.283 137.895 1.00 17.26  ? 39  ARG A NE  1 
ATOM 311  C CZ  . ARG A 1 39  ? -47.159 -19.170 138.808 1.00 17.26  ? 39  ARG A CZ  1 
ATOM 312  N NH1 . ARG A 1 39  ? -48.413 -19.570 138.917 1.00 17.26  ? 39  ARG A NH1 1 
ATOM 313  N NH2 . ARG A 1 39  ? -46.251 -19.658 139.647 1.00 17.26  ? 39  ARG A NH2 1 
ATOM 314  N N   . GLU A 1 40  ? -46.482 -15.753 132.490 1.00 17.19  ? 40  GLU A N   1 
ATOM 315  C CA  . GLU A 1 40  ? -45.346 -16.258 131.727 1.00 17.19  ? 40  GLU A CA  1 
ATOM 316  C C   . GLU A 1 40  ? -44.499 -15.105 131.207 1.00 17.19  ? 40  GLU A C   1 
ATOM 317  O O   . GLU A 1 40  ? -43.266 -15.146 131.281 1.00 17.19  ? 40  GLU A O   1 
ATOM 318  C CB  . GLU A 1 40  ? -45.839 -17.144 130.581 1.00 17.19  ? 40  GLU A CB  1 
ATOM 319  C CG  . GLU A 1 40  ? -46.570 -18.402 131.044 1.00 17.19  ? 40  GLU A CG  1 
ATOM 320  C CD  . GLU A 1 40  ? -48.032 -18.155 131.380 1.00 17.19  ? 40  GLU A CD  1 
ATOM 321  O OE1 . GLU A 1 40  ? -48.497 -17.005 131.230 1.00 17.19  ? 40  GLU A OE1 1 
ATOM 322  O OE2 . GLU A 1 40  ? -48.716 -19.113 131.798 1.00 17.19  ? 40  GLU A OE2 1 
ATOM 323  N N   . ALA A 1 41  ? -45.150 -14.068 130.678 1.00 14.97  ? 41  ALA A N   1 
ATOM 324  C CA  . ALA A 1 41  ? -44.423 -12.926 130.139 1.00 14.97  ? 41  ALA A CA  1 
ATOM 325  C C   . ALA A 1 41  ? -43.668 -12.201 131.244 1.00 14.97  ? 41  ALA A C   1 
ATOM 326  O O   . ALA A 1 41  ? -42.518 -11.789 131.059 1.00 14.97  ? 41  ALA A O   1 
ATOM 327  C CB  . ALA A 1 41  ? -45.387 -11.979 129.428 1.00 14.97  ? 41  ALA A CB  1 
ATOM 328  N N   . LEU A 1 42  ? -44.307 -12.032 132.404 1.00 14.09  ? 42  LEU A N   1 
ATOM 329  C CA  . LEU A 1 42  ? -43.684 -11.303 133.502 1.00 14.09  ? 42  LEU A CA  1 
ATOM 330  C C   . LEU A 1 42  ? -42.441 -12.029 133.986 1.00 14.09  ? 42  LEU A C   1 
ATOM 331  O O   . LEU A 1 42  ? -41.438 -11.396 134.335 1.00 14.09  ? 42  LEU A O   1 
ATOM 332  C CB  . LEU A 1 42  ? -44.683 -11.109 134.642 1.00 14.09  ? 42  LEU A CB  1 
ATOM 333  C CG  . LEU A 1 42  ? -45.801 -10.098 134.372 1.00 14.09  ? 42  LEU A CG  1 
ATOM 334  C CD1 . LEU A 1 42  ? -46.808 -10.105 135.508 1.00 14.09  ? 42  LEU A CD1 1 
ATOM 335  C CD2 . LEU A 1 42  ? -45.245 -8.697  134.169 1.00 14.09  ? 42  LEU A CD2 1 
ATOM 336  N N   . GLU A 1 43  ? -42.486 -13.360 134.026 1.00 15.87  ? 43  GLU A N   1 
ATOM 337  C CA  . GLU A 1 43  ? -41.340 -14.109 134.523 1.00 15.87  ? 43  GLU A CA  1 
ATOM 338  C C   . GLU A 1 43  ? -40.273 -14.321 133.452 1.00 15.87  ? 43  GLU A C   1 
ATOM 339  O O   . GLU A 1 43  ? -39.197 -14.838 133.767 1.00 15.87  ? 43  GLU A O   1 
ATOM 340  C CB  . GLU A 1 43  ? -41.802 -15.460 135.073 1.00 15.87  ? 43  GLU A CB  1 
ATOM 341  C CG  . GLU A 1 43  ? -42.773 -15.343 136.240 1.00 15.87  ? 43  GLU A CG  1 
ATOM 342  C CD  . GLU A 1 43  ? -43.243 -16.689 136.754 1.00 15.87  ? 43  GLU A CD  1 
ATOM 343  O OE1 . GLU A 1 43  ? -42.973 -17.708 136.085 1.00 15.87  ? 43  GLU A OE1 1 
ATOM 344  O OE2 . GLU A 1 43  ? -43.871 -16.730 137.832 1.00 15.87  ? 43  GLU A OE2 1 
ATOM 345  N N   . SER A 1 44  ? -40.547 -13.940 132.204 1.00 15.38  ? 44  SER A N   1 
ATOM 346  C CA  . SER A 1 44  ? -39.613 -14.171 131.114 1.00 15.38  ? 44  SER A CA  1 
ATOM 347  C C   . SER A 1 44  ? -38.378 -13.271 131.232 1.00 15.38  ? 44  SER A C   1 
ATOM 348  O O   . SER A 1 44  ? -38.445 -12.177 131.800 1.00 15.38  ? 44  SER A O   1 
ATOM 349  C CB  . SER A 1 44  ? -40.297 -13.933 129.771 1.00 15.38  ? 44  SER A CB  1 
ATOM 350  O OG  . SER A 1 44  ? -40.247 -12.564 129.406 1.00 15.38  ? 44  SER A OG  1 
ATOM 351  N N   . PRO A 1 45  ? -37.232 -13.721 130.705 1.00 15.91  ? 45  PRO A N   1 
ATOM 352  C CA  . PRO A 1 45  ? -36.011 -12.894 130.738 1.00 15.91  ? 45  PRO A CA  1 
ATOM 353  C C   . PRO A 1 45  ? -35.962 -11.759 129.721 1.00 15.91  ? 45  PRO A C   1 
ATOM 354  O O   . PRO A 1 45  ? -35.102 -10.878 129.853 1.00 15.91  ? 45  PRO A O   1 
ATOM 355  C CB  . PRO A 1 45  ? -34.901 -13.918 130.461 1.00 15.91  ? 45  PRO A CB  1 
ATOM 356  C CG  . PRO A 1 45  ? -35.557 -14.901 129.565 1.00 15.91  ? 45  PRO A CG  1 
ATOM 357  C CD  . PRO A 1 45  ? -36.967 -15.040 130.102 1.00 15.91  ? 45  PRO A CD  1 
ATOM 358  N N   . GLU A 1 46  ? -36.824 -11.760 128.710 1.00 16.47  ? 46  GLU A N   1 
ATOM 359  C CA  . GLU A 1 46  ? -36.901 -10.674 127.739 1.00 16.47  ? 46  GLU A CA  1 
ATOM 360  C C   . GLU A 1 46  ? -37.697 -9.488  128.277 1.00 16.47  ? 46  GLU A C   1 
ATOM 361  O O   . GLU A 1 46  ? -38.604 -9.642  129.099 1.00 16.47  ? 46  GLU A O   1 
ATOM 362  C CB  . GLU A 1 46  ? -37.540 -11.177 126.443 1.00 16.47  ? 46  GLU A CB  1 
ATOM 363  C CG  . GLU A 1 46  ? -36.854 -12.399 125.846 1.00 16.47  ? 46  GLU A CG  1 
ATOM 364  C CD  . GLU A 1 46  ? -35.375 -12.177 125.603 1.00 16.47  ? 46  GLU A CD  1 
ATOM 365  O OE1 . GLU A 1 46  ? -34.553 -12.825 126.287 1.00 16.47  ? 46  GLU A OE1 1 
ATOM 366  O OE2 . GLU A 1 46  ? -35.034 -11.355 124.727 1.00 16.47  ? 46  GLU A OE2 1 
ATOM 367  N N   . HIS A 1 47  ? -37.341 -8.289  127.803 1.00 15.30  ? 47  HIS A N   1 
ATOM 368  C CA  . HIS A 1 47  ? -38.100 -7.086  128.142 1.00 15.30  ? 47  HIS A CA  1 
ATOM 369  C C   . HIS A 1 47  ? -39.273 -7.011  127.175 1.00 15.30  ? 47  HIS A C   1 
ATOM 370  O O   . HIS A 1 47  ? -39.131 -6.502  126.061 1.00 15.30  ? 47  HIS A O   1 
ATOM 371  C CB  . HIS A 1 47  ? -37.269 -5.819  127.929 1.00 15.30  ? 47  HIS A CB  1 
ATOM 372  C CG  . HIS A 1 47  ? -35.866 -5.865  128.449 1.00 15.30  ? 47  HIS A CG  1 
ATOM 373  N ND1 . HIS A 1 47  ? -35.473 -5.225  129.604 1.00 15.30  ? 47  HIS A ND1 1 
ATOM 374  C CD2 . HIS A 1 47  ? -34.750 -6.444  127.942 1.00 15.30  ? 47  HIS A CD2 1 
ATOM 375  C CE1 . HIS A 1 47  ? -34.181 -5.426  129.799 1.00 15.30  ? 47  HIS A CE1 1 
ATOM 376  N NE2 . HIS A 1 47  ? -33.719 -6.162  128.804 1.00 15.30  ? 47  HIS A NE2 1 
ATOM 377  N N   . CYS A 1 48  ? -40.443 -7.523  127.564 1.00 14.12  ? 48  CYS A N   1 
ATOM 378  C CA  . CYS A 1 48  ? -41.524 -7.542  126.586 1.00 14.12  ? 48  CYS A CA  1 
ATOM 379  C C   . CYS A 1 48  ? -41.938 -6.120  126.224 1.00 14.12  ? 48  CYS A C   1 
ATOM 380  O O   . CYS A 1 48  ? -42.129 -5.797  125.047 1.00 14.12  ? 48  CYS A O   1 
ATOM 381  C CB  . CYS A 1 48  ? -42.708 -8.334  127.136 1.00 14.12  ? 48  CYS A CB  1 
ATOM 382  S SG  . CYS A 1 48  ? -42.283 -10.006 127.676 1.00 14.12  ? 48  CYS A SG  1 
ATOM 383  N N   . SER A 1 49  ? -42.078 -5.262  127.231 1.00 13.04  ? 49  SER A N   1 
ATOM 384  C CA  . SER A 1 49  ? -42.519 -3.884  127.057 1.00 13.04  ? 49  SER A CA  1 
ATOM 385  C C   . SER A 1 49  ? -42.112 -3.103  128.300 1.00 13.04  ? 49  SER A C   1 
ATOM 386  O O   . SER A 1 49  ? -41.768 -3.704  129.325 1.00 13.04  ? 49  SER A O   1 
ATOM 387  C CB  . SER A 1 49  ? -44.038 -3.791  126.824 1.00 13.04  ? 49  SER A CB  1 
ATOM 388  O OG  . SER A 1 49  ? -44.761 -3.752  128.038 1.00 13.04  ? 49  SER A OG  1 
ATOM 389  N N   . PRO A 1 50  ? -42.136 -1.771  128.246 1.00 12.87  ? 50  PRO A N   1 
ATOM 390  C CA  . PRO A 1 50  ? -41.873 -0.995  129.470 1.00 12.87  ? 50  PRO A CA  1 
ATOM 391  C C   . PRO A 1 50  ? -42.919 -1.235  130.553 1.00 12.87  ? 50  PRO A C   1 
ATOM 392  O O   . PRO A 1 50  ? -42.602 -1.183  131.752 1.00 12.87  ? 50  PRO A O   1 
ATOM 393  C CB  . PRO A 1 50  ? -41.868 0.458   128.970 1.00 12.87  ? 50  PRO A CB  1 
ATOM 394  C CG  . PRO A 1 50  ? -42.694 0.438   127.741 1.00 12.87  ? 50  PRO A CG  1 
ATOM 395  C CD  . PRO A 1 50  ? -42.421 -0.895  127.098 1.00 12.87  ? 50  PRO A CD  1 
ATOM 396  N N   . HIS A 1 51  ? -44.180 -1.366  130.115 1.00 12.20  ? 51  HIS A N   1 
ATOM 397  C CA  . HIS A 1 51  ? -45.332 -1.581  131.024 1.00 12.20  ? 51  HIS A CA  1 
ATOM 398  C C   . HIS A 1 51  ? -45.120 -2.873  131.801 1.00 12.20  ? 51  HIS A C   1 
ATOM 399  O O   . HIS A 1 51  ? -45.391 -2.855  132.988 1.00 12.20  ? 51  HIS A O   1 
ATOM 400  C CB  . HIS A 1 51  ? -46.648 -1.640  130.241 1.00 12.20  ? 51  HIS A CB  1 
ATOM 401  C CG  . HIS A 1 51  ? -47.129 -0.316  129.751 1.00 12.20  ? 51  HIS A CG  1 
ATOM 402  N ND1 . HIS A 1 51  ? -48.112 0.401   130.406 1.00 12.20  ? 51  HIS A ND1 1 
ATOM 403  C CD2 . HIS A 1 51  ? -46.778 0.418   128.673 1.00 12.20  ? 51  HIS A CD2 1 
ATOM 404  C CE1 . HIS A 1 51  ? -48.343 1.523   129.754 1.00 12.20  ? 51  HIS A CE1 1 
ATOM 405  N NE2 . HIS A 1 51  ? -47.541 1.554   128.683 1.00 12.20  ? 51  HIS A NE2 1 
ATOM 406  N N   . HIS A 1 52  ? -44.618 -3.912  131.127 1.00 12.64  ? 52  HIS A N   1 
ATOM 407  C CA  . HIS A 1 52  ? -44.328 -5.240  131.725 1.00 12.64  ? 52  HIS A CA  1 
ATOM 408  C C   . HIS A 1 52  ? -43.300 -5.057  132.823 1.00 12.64  ? 52  HIS A C   1 
ATOM 409  O O   . HIS A 1 52  ? -43.463 -5.668  133.870 1.00 12.64  ? 52  HIS A O   1 
ATOM 410  C CB  . HIS A 1 52  ? -43.795 -6.191  130.654 1.00 12.64  ? 52  HIS A CB  1 
ATOM 411  C CG  . HIS A 1 52  ? -44.819 -7.063  130.016 1.00 12.64  ? 52  HIS A CG  1 
ATOM 412  N ND1 . HIS A 1 52  ? -45.373 -8.138  130.674 1.00 12.64  ? 52  HIS A ND1 1 
ATOM 413  C CD2 . HIS A 1 52  ? -45.359 -7.051  128.782 1.00 12.64  ? 52  HIS A CD2 1 
ATOM 414  C CE1 . HIS A 1 52  ? -46.230 -8.740  129.877 1.00 12.64  ? 52  HIS A CE1 1 
ATOM 415  N NE2 . HIS A 1 52  ? -46.239 -8.092  128.711 1.00 12.64  ? 52  HIS A NE2 1 
ATOM 416  N N   . THR A 1 53  ? -42.271 -4.274  132.569 1.00 12.46  ? 53  THR A N   1 
ATOM 417  C CA  . THR A 1 53  ? -41.192 -3.944  133.538 1.00 12.46  ? 53  THR A CA  1 
ATOM 418  C C   . THR A 1 53  ? -41.816 -3.223  134.732 1.00 12.46  ? 53  THR A C   1 
ATOM 419  O O   . THR A 1 53  ? -41.549 -3.650  135.876 1.00 12.46  ? 53  THR A O   1 
ATOM 420  C CB  . THR A 1 53  ? -40.101 -3.092  132.880 1.00 12.46  ? 53  THR A CB  1 
ATOM 421  O OG1 . THR A 1 53  ? -39.623 -3.797  131.734 1.00 12.46  ? 53  THR A OG1 1 
ATOM 422  C CG2 . THR A 1 53  ? -38.952 -2.787  133.814 1.00 12.46  ? 53  THR A CG2 1 
ATOM 423  N N   . ALA A 1 54  ? -42.648 -2.207  134.484 1.00 12.24  ? 54  ALA A N   1 
ATOM 424  C CA  . ALA A 1 54  ? -43.286 -1.404  135.552 1.00 12.24  ? 54  ALA A CA  1 
ATOM 425  C C   . ALA A 1 54  ? -44.142 -2.326  136.422 1.00 12.24  ? 54  ALA A C   1 
ATOM 426  O O   . ALA A 1 54  ? -44.057 -2.197  137.651 1.00 12.24  ? 54  ALA A O   1 
ATOM 427  C CB  . ALA A 1 54  ? -44.110 -0.300  134.943 1.00 12.24  ? 54  ALA A CB  1 
ATOM 428  N N   . LEU A 1 55  ? -44.903 -3.236  135.812 1.00 12.95  ? 55  LEU A N   1 
ATOM 429  C CA  . LEU A 1 55  ? -45.801 -4.169  136.536 1.00 12.95  ? 55  LEU A CA  1 
ATOM 430  C C   . LEU A 1 55  ? -44.939 -5.048  137.438 1.00 12.95  ? 55  LEU A C   1 
ATOM 431  O O   . LEU A 1 55  ? -45.293 -5.179  138.605 1.00 12.95  ? 55  LEU A O   1 
ATOM 432  C CB  . LEU A 1 55  ? -46.586 -5.013  135.526 1.00 12.95  ? 55  LEU A CB  1 
ATOM 433  C CG  . LEU A 1 55  ? -47.857 -5.665  136.067 1.00 12.95  ? 55  LEU A CG  1 
ATOM 434  C CD1 . LEU A 1 55  ? -48.922 -4.619  136.357 1.00 12.95  ? 55  LEU A CD1 1 
ATOM 435  C CD2 . LEU A 1 55  ? -48.390 -6.707  135.097 1.00 12.95  ? 55  LEU A CD2 1 
ATOM 436  N N   . ARG A 1 56  ? -43.836 -5.592  136.920 1.00 13.17  ? 56  ARG A N   1 
ATOM 437  C CA  . ARG A 1 56  ? -42.905 -6.431  137.717 1.00 13.17  ? 56  ARG A CA  1 
ATOM 438  C C   . ARG A 1 56  ? -42.416 -5.613  138.912 1.00 13.17  ? 56  ARG A C   1 
ATOM 439  O O   . ARG A 1 56  ? -42.496 -6.128  140.047 1.00 13.17  ? 56  ARG A O   1 
ATOM 440  C CB  . ARG A 1 56  ? -41.728 -6.892  136.852 1.00 13.17  ? 56  ARG A CB  1 
ATOM 441  C CG  . ARG A 1 56  ? -42.133 -7.770  135.679 1.00 13.17  ? 56  ARG A CG  1 
ATOM 442  C CD  . ARG A 1 56  ? -41.261 -7.536  134.463 1.00 13.17  ? 56  ARG A CD  1 
ATOM 443  N NE  . ARG A 1 56  ? -41.753 -8.231  133.285 1.00 13.17  ? 56  ARG A NE  1 
ATOM 444  C CZ  . ARG A 1 56  ? -41.279 -8.070  132.053 1.00 13.17  ? 56  ARG A CZ  1 
ATOM 445  N NH1 . ARG A 1 56  ? -40.300 -7.213  131.817 1.00 13.17  ? 56  ARG A NH1 1 
ATOM 446  N NH2 . ARG A 1 56  ? -41.802 -8.758  131.054 1.00 13.17  ? 56  ARG A NH2 1 
ATOM 447  N N   . GLN A 1 57  ? -41.970 -4.373  138.679 1.00 12.99  ? 57  GLN A N   1 
ATOM 448  C CA  . GLN A 1 57  ? -41.457 -3.501  139.769 1.00 12.99  ? 57  GLN A CA  1 
ATOM 449  C C   . GLN A 1 57  ? -42.551 -3.364  140.827 1.00 12.99  ? 57  GLN A C   1 
ATOM 450  O O   . GLN A 1 57  ? -42.250 -3.617  142.007 1.00 12.99  ? 57  GLN A O   1 
ATOM 451  C CB  . GLN A 1 57  ? -41.061 -2.118  139.247 1.00 12.99  ? 57  GLN A CB  1 
ATOM 452  C CG  . GLN A 1 57  ? -40.056 -2.143  138.103 1.00 12.99  ? 57  GLN A CG  1 
ATOM 453  C CD  . GLN A 1 57  ? -39.124 -3.327  138.176 1.00 12.99  ? 57  GLN A CD  1 
ATOM 454  O OE1 . GLN A 1 57  ? -38.401 -3.513  139.152 1.00 12.99  ? 57  GLN A OE1 1 
ATOM 455  N NE2 . GLN A 1 57  ? -39.132 -4.141  137.133 1.00 12.99  ? 57  GLN A NE2 1 
ATOM 456  N N   . ALA A 1 58  ? -43.779 -3.037  140.421 1.00 12.72  ? 58  ALA A N   1 
ATOM 457  C CA  . ALA A 1 58  ? -44.913 -2.816  141.347 1.00 12.72  ? 58  ALA A CA  1 
ATOM 458  C C   . ALA A 1 58  ? -45.160 -4.088  142.153 1.00 12.72  ? 58  ALA A C   1 
ATOM 459  O O   . ALA A 1 58  ? -45.312 -3.977  143.377 1.00 12.72  ? 58  ALA A O   1 
ATOM 460  C CB  . ALA A 1 58  ? -46.129 -2.419  140.549 1.00 12.72  ? 58  ALA A CB  1 
ATOM 461  N N   . ILE A 1 59  ? -45.186 -5.247  141.496 1.00 13.61  ? 59  ILE A N   1 
ATOM 462  C CA  . ILE A 1 59  ? -45.421 -6.563  142.152 1.00 13.61  ? 59  ILE A CA  1 
ATOM 463  C C   . ILE A 1 59  ? -44.352 -6.746  143.228 1.00 13.61  ? 59  ILE A C   1 
ATOM 464  O O   . ILE A 1 59  ? -44.732 -6.996  144.377 1.00 13.61  ? 59  ILE A O   1 
ATOM 465  C CB  . ILE A 1 59  ? -45.393 -7.696  141.108 1.00 13.61  ? 59  ILE A CB  1 
ATOM 466  C CG1 . ILE A 1 59  ? -46.563 -7.596  140.125 1.00 13.61  ? 59  ILE A CG1 1 
ATOM 467  C CG2 . ILE A 1 59  ? -45.348 -9.058  141.783 1.00 13.61  ? 59  ILE A CG2 1 
ATOM 468  C CD1 . ILE A 1 59  ? -46.344 -8.354  138.836 1.00 13.61  ? 59  ILE A CD1 1 
ATOM 469  N N   . LEU A 1 60  ? -43.064 -6.812  142.863 1.00 14.24  ? 60  LEU A N   1 
ATOM 470  C CA  . LEU A 1 60  ? -41.927 -7.088  143.792 1.00 14.24  ? 60  LEU A CA  1 
ATOM 471  C C   . LEU A 1 60  ? -41.893 -6.140  144.989 1.00 14.24  ? 60  LEU A C   1 
ATOM 472  O O   . LEU A 1 60  ? -41.561 -6.616  146.062 1.00 14.24  ? 60  LEU A O   1 
ATOM 473  C CB  . LEU A 1 60  ? -40.609 -7.005  143.019 1.00 14.24  ? 60  LEU A CB  1 
ATOM 474  C CG  . LEU A 1 60  ? -40.240 -8.243  142.208 1.00 14.24  ? 60  LEU A CG  1 
ATOM 475  C CD1 . LEU A 1 60  ? -38.974 -8.011  141.405 1.00 14.24  ? 60  LEU A CD1 1 
ATOM 476  C CD2 . LEU A 1 60  ? -40.079 -9.454  143.111 1.00 14.24  ? 60  LEU A CD2 1 
ATOM 477  N N   . CYS A 1 61  ? -42.189 -4.858  144.822 1.00 16.11  ? 61  CYS A N   1 
ATOM 478  C CA  . CYS A 1 61  ? -42.302 -3.896  145.941 1.00 16.11  ? 61  CYS A CA  1 
ATOM 479  C C   . CYS A 1 61  ? -43.523 -4.213  146.836 1.00 16.11  ? 61  CYS A C   1 
ATOM 480  O O   . CYS A 1 61  ? -43.312 -4.243  148.019 1.00 16.11  ? 61  CYS A O   1 
ATOM 481  C CB  . CYS A 1 61  ? -42.346 -2.485  145.378 1.00 16.11  ? 61  CYS A CB  1 
ATOM 482  S SG  . CYS A 1 61  ? -42.399 -1.193  146.640 1.00 16.11  ? 61  CYS A SG  1 
ATOM 483  N N   . TRP A 1 62  ? -44.735 -4.452  146.314 1.00 15.37  ? 62  TRP A N   1 
ATOM 484  C CA  . TRP A 1 62  ? -45.940 -4.817  147.108 1.00 15.37  ? 62  TRP A CA  1 
ATOM 485  C C   . TRP A 1 62  ? -45.587 -6.043  147.907 1.00 15.37  ? 62  TRP A C   1 
ATOM 486  O O   . TRP A 1 62  ? -46.038 -6.163  149.012 1.00 15.37  ? 62  TRP A O   1 
ATOM 487  C CB  . TRP A 1 62  ? -47.157 -5.131  146.244 1.00 15.37  ? 62  TRP A CB  1 
ATOM 488  C CG  . TRP A 1 62  ? -48.364 -5.466  147.063 1.00 15.37  ? 62  TRP A CG  1 
ATOM 489  C CD1 . TRP A 1 62  ? -48.971 -6.681  147.178 1.00 15.37  ? 62  TRP A CD1 1 
ATOM 490  C CD2 . TRP A 1 62  ? -49.099 -4.569  147.914 1.00 15.37  ? 62  TRP A CD2 1 
ATOM 491  N NE1 . TRP A 1 62  ? -50.038 -6.598  148.027 1.00 15.37  ? 62  TRP A NE1 1 
ATOM 492  C CE2 . TRP A 1 62  ? -50.141 -5.316  148.494 1.00 15.37  ? 62  TRP A CE2 1 
ATOM 493  C CE3 . TRP A 1 62  ? -48.978 -3.213  148.239 1.00 15.37  ? 62  TRP A CE3 1 
ATOM 494  C CZ2 . TRP A 1 62  ? -51.056 -4.751  149.381 1.00 15.37  ? 62  TRP A CZ2 1 
ATOM 495  C CZ3 . TRP A 1 62  ? -49.883 -2.655  149.114 1.00 15.37  ? 62  TRP A CZ3 1 
ATOM 496  C CH2 . TRP A 1 62  ? -50.908 -3.416  149.676 1.00 15.37  ? 62  TRP A CH2 1 
ATOM 497  N N   . GLY A 1 63  ? -44.883 -6.959  147.276 1.00 17.16  ? 63  GLY A N   1 
ATOM 498  C CA  . GLY A 1 63  ? -44.365 -8.150  147.973 1.00 17.16  ? 63  GLY A CA  1 
ATOM 499  C C   . GLY A 1 63  ? -43.531 -7.737  149.167 1.00 17.16  ? 63  GLY A C   1 
ATOM 500  O O   . GLY A 1 63  ? -43.797 -8.260  150.255 1.00 17.16  ? 63  GLY A O   1 
ATOM 501  N N   . GLU A 1 64  ? -42.594 -6.803  148.986 1.00 18.82  ? 64  GLU A N   1 
ATOM 502  C CA  . GLU A 1 64  ? -41.731 -6.298  150.088 1.00 18.82  ? 64  GLU A CA  1 
ATOM 503  C C   . GLU A 1 64  ? -42.614 -5.654  151.159 1.00 18.82  ? 64  GLU A C   1 
ATOM 504  O O   . GLU A 1 64  ? -42.319 -5.834  152.364 1.00 18.82  ? 64  GLU A O   1 
ATOM 505  C CB  . GLU A 1 64  ? -40.708 -5.301  149.541 1.00 18.82  ? 64  GLU A CB  1 
ATOM 506  C CG  . GLU A 1 64  ? -39.630 -5.945  148.688 1.00 18.82  ? 64  GLU A CG  1 
ATOM 507  C CD  . GLU A 1 64  ? -38.646 -6.816  149.452 1.00 18.82  ? 64  GLU A CD  1 
ATOM 508  O OE1 . GLU A 1 64  ? -37.867 -7.536  148.798 1.00 18.82  ? 64  GLU A OE1 1 
ATOM 509  O OE2 . GLU A 1 64  ? -38.659 -6.769  150.698 1.00 18.82  ? 64  GLU A OE2 1 
ATOM 510  N N   . LEU A 1 65  ? -43.659 -4.929  150.748 1.00 18.73  ? 65  LEU A N   1 
ATOM 511  C CA  . LEU A 1 65  ? -44.593 -4.268  151.699 1.00 18.73  ? 65  LEU A CA  1 
ATOM 512  C C   . LEU A 1 65  ? -45.267 -5.343  152.553 1.00 18.73  ? 65  LEU A C   1 
ATOM 513  O O   . LEU A 1 65  ? -45.276 -5.185  153.791 1.00 18.73  ? 65  LEU A O   1 
ATOM 514  C CB  . LEU A 1 65  ? -45.625 -3.457  150.912 1.00 18.73  ? 65  LEU A CB  1 
ATOM 515  C CG  . LEU A 1 65  ? -45.098 -2.177  150.265 1.00 18.73  ? 65  LEU A CG  1 
ATOM 516  C CD1 . LEU A 1 65  ? -46.211 -1.440  149.538 1.00 18.73  ? 65  LEU A CD1 1 
ATOM 517  C CD2 . LEU A 1 65  ? -44.443 -1.274  151.297 1.00 18.73  ? 65  LEU A CD2 1 
ATOM 518  N N   . MET A 1 66  ? -45.783 -6.405  151.928 1.00 20.26  ? 66  MET A N   1 
ATOM 519  C CA  . MET A 1 66  ? -46.480 -7.502  152.648 1.00 20.26  ? 66  MET A CA  1 
ATOM 520  C C   . MET A 1 66  ? -45.462 -8.185  153.558 1.00 20.26  ? 66  MET A C   1 
ATOM 521  O O   . MET A 1 66  ? -45.856 -8.608  154.655 1.00 20.26  ? 66  MET A O   1 
ATOM 522  C CB  . MET A 1 66  ? -47.073 -8.524  151.674 1.00 20.26  ? 66  MET A CB  1 
ATOM 523  C CG  . MET A 1 66  ? -48.102 -7.947  150.714 1.00 20.26  ? 66  MET A CG  1 
ATOM 524  S SD  . MET A 1 66  ? -49.286 -6.816  151.490 1.00 20.26  ? 66  MET A SD  1 
ATOM 525  C CE  . MET A 1 66  ? -48.504 -5.235  151.168 1.00 20.26  ? 66  MET A CE  1 
ATOM 526  N N   . THR A 1 67  ? -44.202 -8.278  153.128 1.00 22.16  ? 67  THR A N   1 
ATOM 527  C CA  . THR A 1 67  ? -43.108 -8.895  153.918 1.00 22.16  ? 67  THR A CA  1 
ATOM 528  C C   . THR A 1 67  ? -42.934 -8.088  155.203 1.00 22.16  ? 67  THR A C   1 
ATOM 529  O O   . THR A 1 67  ? -42.919 -8.712  156.273 1.00 22.16  ? 67  THR A O   1 
ATOM 530  C CB  . THR A 1 67  ? -41.799 -8.945  153.123 1.00 22.16  ? 67  THR A CB  1 
ATOM 531  O OG1 . THR A 1 67  ? -42.001 -9.759  151.966 1.00 22.16  ? 67  THR A OG1 1 
ATOM 532  C CG2 . THR A 1 67  ? -40.644 -9.482  153.937 1.00 22.16  ? 67  THR A CG2 1 
ATOM 533  N N   . LEU A 1 68  ? -42.836 -6.759  155.096 1.00 23.95  ? 68  LEU A N   1 
ATOM 534  C CA  . LEU A 1 68  ? -42.688 -5.875  156.283 1.00 23.95  ? 68  LEU A CA  1 
ATOM 535  C C   . LEU A 1 68  ? -43.938 -5.997  157.155 1.00 23.95  ? 68  LEU A C   1 
ATOM 536  O O   . LEU A 1 68  ? -43.797 -5.940  158.395 1.00 23.95  ? 68  LEU A O   1 
ATOM 537  C CB  . LEU A 1 68  ? -42.478 -4.432  155.820 1.00 23.95  ? 68  LEU A CB  1 
ATOM 538  C CG  . LEU A 1 68  ? -42.794 -3.350  156.854 1.00 23.95  ? 68  LEU A CG  1 
ATOM 539  C CD1 . LEU A 1 68  ? -41.943 -3.513  158.104 1.00 23.95  ? 68  LEU A CD1 1 
ATOM 540  C CD2 . LEU A 1 68  ? -42.595 -1.968  156.255 1.00 23.95  ? 68  LEU A CD2 1 
ATOM 541  N N   . ALA A 1 69  ? -45.123 -6.089  156.547 1.00 25.89  ? 69  ALA A N   1 
ATOM 542  C CA  . ALA A 1 69  ? -46.395 -6.257  157.285 1.00 25.89  ? 69  ALA A CA  1 
ATOM 543  C C   . ALA A 1 69  ? -46.302 -7.565  158.070 1.00 25.89  ? 69  ALA A C   1 
ATOM 544  O O   . ALA A 1 69  ? -46.614 -7.561  159.281 1.00 25.89  ? 69  ALA A O   1 
ATOM 545  C CB  . ALA A 1 69  ? -47.557 -6.252  156.325 1.00 25.89  ? 69  ALA A CB  1 
ATOM 546  N N   . THR A 1 70  ? -45.852 -8.640  157.421 1.00 27.92  ? 70  THR A N   1 
ATOM 547  C CA  . THR A 1 70  ? -45.660 -9.952  158.086 1.00 27.92  ? 70  THR A CA  1 
ATOM 548  C C   . THR A 1 70  ? -44.650 -9.753  159.215 1.00 27.92  ? 70  THR A C   1 
ATOM 549  O O   . THR A 1 70  ? -44.844 -10.360 160.282 1.00 27.92  ? 70  THR A O   1 
ATOM 550  C CB  . THR A 1 70  ? -45.205 -11.017 157.082 1.00 27.92  ? 70  THR A CB  1 
ATOM 551  O OG1 . THR A 1 70  ? -46.229 -11.175 156.098 1.00 27.92  ? 70  THR A OG1 1 
ATOM 552  C CG2 . THR A 1 70  ? -44.911 -12.349 157.735 1.00 27.92  ? 70  THR A CG2 1 
ATOM 553  N N   . TRP A 1 71  ? -43.635 -8.912  159.000 1.00 29.25  ? 71  TRP A N   1 
ATOM 554  C CA  . TRP A 1 71  ? -42.574 -8.653  160.010 1.00 29.25  ? 71  TRP A CA  1 
ATOM 555  C C   . TRP A 1 71  ? -43.179 -8.004  161.259 1.00 29.25  ? 71  TRP A C   1 
ATOM 556  O O   . TRP A 1 71  ? -42.812 -8.437  162.366 1.00 29.25  ? 71  TRP A O   1 
ATOM 557  C CB  . TRP A 1 71  ? -41.447 -7.798  159.418 1.00 29.25  ? 71  TRP A CB  1 
ATOM 558  C CG  . TRP A 1 71  ? -40.491 -7.320  160.463 1.00 29.25  ? 71  TRP A CG  1 
ATOM 559  C CD1 . TRP A 1 71  ? -39.385 -7.968  160.929 1.00 29.25  ? 71  TRP A CD1 1 
ATOM 560  C CD2 . TRP A 1 71  ? -40.583 -6.098  161.213 1.00 29.25  ? 71  TRP A CD2 1 
ATOM 561  N NE1 . TRP A 1 71  ? -38.774 -7.228  161.906 1.00 29.25  ? 71  TRP A NE1 1 
ATOM 562  C CE2 . TRP A 1 71  ? -39.487 -6.074  162.101 1.00 29.25  ? 71  TRP A CE2 1 
ATOM 563  C CE3 . TRP A 1 71  ? -41.477 -5.021  161.213 1.00 29.25  ? 71  TRP A CE3 1 
ATOM 564  C CZ2 . TRP A 1 71  ? -39.265 -5.014  162.977 1.00 29.25  ? 71  TRP A CZ2 1 
ATOM 565  C CZ3 . TRP A 1 71  ? -41.254 -3.975  162.080 1.00 29.25  ? 71  TRP A CZ3 1 
ATOM 566  C CH2 . TRP A 1 71  ? -40.165 -3.976  162.948 1.00 29.25  ? 71  TRP A CH2 1 
ATOM 567  N N   . VAL A 1 72  ? -44.061 -7.009  161.101 1.00 31.57  ? 72  VAL A N   1 
ATOM 568  C CA  . VAL A 1 72  ? -44.721 -6.323  162.256 1.00 31.57  ? 72  VAL A CA  1 
ATOM 569  C C   . VAL A 1 72  ? -45.697 -7.307  162.907 1.00 31.57  ? 72  VAL A C   1 
ATOM 570  O O   . VAL A 1 72  ? -45.879 -7.225  164.137 1.00 31.57  ? 72  VAL A O   1 
ATOM 571  C CB  . VAL A 1 72  ? -45.432 -5.007  161.873 1.00 31.57  ? 72  VAL A CB  1 
ATOM 572  C CG1 . VAL A 1 72  ? -44.453 -3.961  161.371 1.00 31.57  ? 72  VAL A CG1 1 
ATOM 573  C CG2 . VAL A 1 72  ? -46.562 -5.208  160.879 1.00 31.57  ? 72  VAL A CG2 1 
ATOM 574  N N   . GLY A 1 73  ? -46.299 -8.204  162.123 1.00 34.06  ? 73  GLY A N   1 
ATOM 575  C CA  . GLY A 1 73  ? -47.274 -9.178  162.652 1.00 34.06  ? 73  GLY A CA  1 
ATOM 576  C C   . GLY A 1 73  ? -46.615 -10.206 163.558 1.00 34.06  ? 73  GLY A C   1 
ATOM 577  O O   . GLY A 1 73  ? -47.309 -10.705 164.472 1.00 34.06  ? 73  GLY A O   1 
ATOM 578  N N   . VAL A 1 74  ? -45.328 -10.504 163.348 1.00 36.06  ? 74  VAL A N   1 
ATOM 579  C CA  . VAL A 1 74  ? -44.601 -11.564 164.113 1.00 36.06  ? 74  VAL A CA  1 
ATOM 580  C C   . VAL A 1 74  ? -43.676 -10.964 165.182 1.00 36.06  ? 74  VAL A C   1 
ATOM 581  O O   . VAL A 1 74  ? -43.333 -11.713 166.133 1.00 36.06  ? 74  VAL A O   1 
ATOM 582  C CB  . VAL A 1 74  ? -43.814 -12.456 163.134 1.00 30.00  ? 74  VAL A CB  1 
ATOM 583  C CG1 . VAL A 1 74  ? -42.942 -13.469 163.859 1.00 30.00  ? 74  VAL A CG1 1 
ATOM 584  C CG2 . VAL A 1 74  ? -44.733 -13.154 162.146 1.00 30.00  ? 74  VAL A CG2 1 
ATOM 585  N N   . ASN A 1 75  ? -43.313 -9.680  165.087 1.00 35.35  ? 75  ASN A N   1 
ATOM 586  C CA  . ASN A 1 75  ? -42.306 -9.080  166.010 1.00 35.35  ? 75  ASN A CA  1 
ATOM 587  C C   . ASN A 1 75  ? -42.938 -8.122  167.023 1.00 35.35  ? 75  ASN A C   1 
ATOM 588  O O   . ASN A 1 75  ? -42.687 -8.299  168.245 1.00 35.35  ? 75  ASN A O   1 
ATOM 589  C CB  . ASN A 1 75  ? -41.212 -8.365  165.214 1.00 35.35  ? 75  ASN A CB  1 
ATOM 590  C CG  . ASN A 1 75  ? -40.332 -9.332  164.453 1.00 35.35  ? 75  ASN A CG  1 
ATOM 591  O OD1 . ASN A 1 75  ? -40.283 -9.304  163.226 1.00 35.35  ? 75  ASN A OD1 1 
ATOM 592  N ND2 . ASN A 1 75  ? -39.650 -10.208 165.171 1.00 35.35  ? 75  ASN A ND2 1 
ATOM 593  N N   . LEU A 1 76  ? -43.709 -7.138  166.544 1.00 37.37  ? 76  LEU A N   1 
ATOM 594  C CA  . LEU A 1 76  ? -44.379 -6.138  167.419 1.00 37.37  ? 76  LEU A CA  1 
ATOM 595  C C   . LEU A 1 76  ? -45.109 -6.877  168.542 1.00 37.37  ? 76  LEU A C   1 
ATOM 596  O O   . LEU A 1 76  ? -45.851 -7.828  168.225 1.00 37.37  ? 76  LEU A O   1 
ATOM 597  C CB  . LEU A 1 76  ? -45.357 -5.302  166.587 1.00 37.37  ? 76  LEU A CB  1 
ATOM 598  C CG  . LEU A 1 76  ? -44.769 -4.096  165.854 1.00 37.37  ? 76  LEU A CG  1 
ATOM 599  C CD1 . LEU A 1 76  ? -43.798 -4.548  164.776 1.00 37.37  ? 76  LEU A CD1 1 
ATOM 600  C CD2 . LEU A 1 76  ? -45.853 -3.219  165.251 1.00 37.37  ? 76  LEU A CD2 1 
ATOM 601  N N   . GLU A 1 77  ? -44.915 -6.460  169.795 1.00 43.55  ? 77  GLU A N   1 
ATOM 602  C CA  . GLU A 1 77  ? -45.571 -7.093  170.973 1.00 43.55  ? 77  GLU A CA  1 
ATOM 603  C C   . GLU A 1 77  ? -46.810 -6.275  171.341 1.00 43.55  ? 77  GLU A C   1 
ATOM 604  O O   . GLU A 1 77  ? -47.479 -6.645  172.326 1.00 43.55  ? 77  GLU A O   1 
ATOM 605  C CB  . GLU A 1 77  ? -44.596 -7.193  172.150 1.00 43.55  ? 77  GLU A CB  1 
ATOM 606  C CG  . GLU A 1 77  ? -44.244 -5.856  172.783 1.00 43.55  ? 77  GLU A CG  1 
ATOM 607  C CD  . GLU A 1 77  ? -43.237 -5.015  172.019 1.00 43.55  ? 77  GLU A CD  1 
ATOM 608  O OE1 . GLU A 1 77  ? -42.646 -5.531  171.050 1.00 43.55  ? 77  GLU A OE1 1 
ATOM 609  O OE2 . GLU A 1 77  ? -43.048 -3.841  172.394 1.00 43.55  ? 77  GLU A OE2 1 
ATOM 610  N N   . ASP A 1 78  ? -47.108 -5.217  170.583 1.00 43.05  ? 78  ASP A N   1 
ATOM 611  C CA  . ASP A 1 78  ? -48.279 -4.339  170.840 1.00 43.05  ? 78  ASP A CA  1 
ATOM 612  C C   . ASP A 1 78  ? -49.363 -4.650  169.805 1.00 43.05  ? 78  ASP A C   1 
ATOM 613  O O   . ASP A 1 78  ? -49.087 -4.477  168.607 1.00 43.05  ? 78  ASP A O   1 
ATOM 614  C CB  . ASP A 1 78  ? -47.868 -2.866  170.806 1.00 43.05  ? 78  ASP A CB  1 
ATOM 615  C CG  . ASP A 1 78  ? -49.020 -1.898  171.020 1.00 43.05  ? 78  ASP A CG  1 
ATOM 616  O OD1 . ASP A 1 78  ? -50.116 -2.362  171.388 1.00 43.05  ? 78  ASP A OD1 1 
ATOM 617  O OD2 . ASP A 1 78  ? -48.808 -0.686  170.814 1.00 43.05  ? 78  ASP A OD2 1 
ATOM 618  N N   . PRO A 1 79  ? -50.569 -5.109  170.204 1.00 41.50  ? 79  PRO A N   1 
ATOM 619  C CA  . PRO A 1 79  ? -51.662 -5.350  169.258 1.00 41.50  ? 79  PRO A CA  1 
ATOM 620  C C   . PRO A 1 79  ? -52.229 -4.040  168.703 1.00 41.50  ? 79  PRO A C   1 
ATOM 621  O O   . PRO A 1 79  ? -52.776 -4.070  167.620 1.00 41.50  ? 79  PRO A O   1 
ATOM 622  C CB  . PRO A 1 79  ? -52.717 -6.079  170.100 1.00 41.50  ? 79  PRO A CB  1 
ATOM 623  C CG  . PRO A 1 79  ? -52.463 -5.581  171.501 1.00 41.50  ? 79  PRO A CG  1 
ATOM 624  C CD  . PRO A 1 79  ? -50.959 -5.420  171.580 1.00 41.50  ? 79  PRO A CD  1 
ATOM 625  N N   . ALA A 1 80  ? -52.130 -2.953  169.458 1.00 40.33  ? 80  ALA A N   1 
ATOM 626  C CA  . ALA A 1 80  ? -52.642 -1.643  169.023 1.00 40.33  ? 80  ALA A CA  1 
ATOM 627  C C   . ALA A 1 80  ? -51.818 -1.200  167.820 1.00 40.33  ? 80  ALA A C   1 
ATOM 628  O O   . ALA A 1 80  ? -52.400 -1.031  166.736 1.00 40.33  ? 80  ALA A O   1 
ATOM 629  C CB  . ALA A 1 80  ? -52.550 -0.656  170.150 1.00 40.33  ? 80  ALA A CB  1 
ATOM 630  N N   . SER A 1 81  ? -50.509 -1.057  167.994 1.00 39.08  ? 81  SER A N   1 
ATOM 631  C CA  . SER A 1 81  ? -49.603 -0.609  166.914 1.00 39.08  ? 81  SER A CA  1 
ATOM 632  C C   . SER A 1 81  ? -49.610 -1.645  165.796 1.00 39.08  ? 81  SER A C   1 
ATOM 633  O O   . SER A 1 81  ? -49.738 -1.247  164.630 1.00 39.08  ? 81  SER A O   1 
ATOM 634  C CB  . SER A 1 81  ? -48.225 -0.388  167.443 1.00 39.08  ? 81  SER A CB  1 
ATOM 635  O OG  . SER A 1 81  ? -47.629 -1.622  167.809 1.00 39.08  ? 81  SER A OG  1 
ATOM 636  N N   . ARG A 1 82  ? -49.493 -2.924  166.139 1.00 38.70  ? 82  ARG A N   1 
ATOM 637  C CA  . ARG A 1 82  ? -49.467 -4.003  165.127 1.00 38.70  ? 82  ARG A CA  1 
ATOM 638  C C   . ARG A 1 82  ? -50.614 -3.739  164.161 1.00 38.70  ? 82  ARG A C   1 
ATOM 639  O O   . ARG A 1 82  ? -50.365 -3.710  162.946 1.00 38.70  ? 82  ARG A O   1 
ATOM 640  C CB  . ARG A 1 82  ? -49.591 -5.369  165.799 1.00 38.70  ? 82  ARG A CB  1 
ATOM 641  C CG  . ARG A 1 82  ? -49.532 -6.542  164.834 1.00 38.70  ? 82  ARG A CG  1 
ATOM 642  C CD  . ARG A 1 82  ? -49.138 -7.828  165.532 1.00 38.70  ? 82  ARG A CD  1 
ATOM 643  N NE  . ARG A 1 82  ? -49.890 -8.041  166.761 1.00 38.70  ? 82  ARG A NE  1 
ATOM 644  C CZ  . ARG A 1 82  ? -49.486 -7.691  167.979 1.00 38.70  ? 82  ARG A CZ  1 
ATOM 645  N NH1 . ARG A 1 82  ? -48.319 -7.097  168.163 1.00 38.70  ? 82  ARG A NH1 1 
ATOM 646  N NH2 . ARG A 1 82  ? -50.257 -7.940  169.022 1.00 38.70  ? 82  ARG A NH2 1 
ATOM 647  N N   . ASP A 1 83  ? -51.811 -3.484  164.680 1.00 37.20  ? 83  ASP A N   1 
ATOM 648  C CA  . ASP A 1 83  ? -53.006 -3.244  163.840 1.00 37.20  ? 83  ASP A CA  1 
ATOM 649  C C   . ASP A 1 83  ? -52.813 -1.959  163.046 1.00 37.20  ? 83  ASP A C   1 
ATOM 650  O O   . ASP A 1 83  ? -52.967 -2.005  161.820 1.00 37.20  ? 83  ASP A O   1 
ATOM 651  C CB  . ASP A 1 83  ? -54.261 -3.156  164.698 1.00 37.20  ? 83  ASP A CB  1 
ATOM 652  C CG  . ASP A 1 83  ? -54.550 -4.426  165.474 1.00 37.20  ? 83  ASP A CG  1 
ATOM 653  O OD1 . ASP A 1 83  ? -53.833 -5.421  165.254 1.00 37.20  ? 83  ASP A OD1 1 
ATOM 654  O OD2 . ASP A 1 83  ? -55.484 -4.405  166.297 1.00 37.20  ? 83  ASP A OD2 1 
ATOM 655  N N   . LEU A 1 84  ? -52.438 -0.854  163.682 1.00 34.52  ? 84  LEU A N   1 
ATOM 656  C CA  . LEU A 1 84  ? -52.318 0.461   162.989 1.00 34.52  ? 84  LEU A CA  1 
ATOM 657  C C   . LEU A 1 84  ? -51.408 0.320   161.772 1.00 34.52  ? 84  LEU A C   1 
ATOM 658  O O   . LEU A 1 84  ? -51.869 0.609   160.667 1.00 34.52  ? 84  LEU A O   1 
ATOM 659  C CB  . LEU A 1 84  ? -51.738 1.514   163.929 1.00 34.52  ? 84  LEU A CB  1 
ATOM 660  C CG  . LEU A 1 84  ? -52.665 2.030   165.024 1.00 34.52  ? 84  LEU A CG  1 
ATOM 661  C CD1 . LEU A 1 84  ? -51.879 2.839   166.042 1.00 34.52  ? 84  LEU A CD1 1 
ATOM 662  C CD2 . LEU A 1 84  ? -53.786 2.866   164.435 1.00 34.52  ? 84  LEU A CD2 1 
ATOM 663  N N   . VAL A 1 85  ? -50.162 -0.095  161.967 1.00 32.22  ? 85  VAL A N   1 
ATOM 664  C CA  . VAL A 1 85  ? -49.160 -0.237  160.868 1.00 32.22  ? 85  VAL A CA  1 
ATOM 665  C C   . VAL A 1 85  ? -49.770 -1.079  159.760 1.00 32.22  ? 85  VAL A C   1 
ATOM 666  O O   . VAL A 1 85  ? -49.852 -0.570  158.617 1.00 32.22  ? 85  VAL A O   1 
ATOM 667  C CB  . VAL A 1 85  ? -47.848 -0.865  161.369 1.00 32.22  ? 85  VAL A CB  1 
ATOM 668  C CG1 . VAL A 1 85  ? -46.887 -1.166  160.233 1.00 32.22  ? 85  VAL A CG1 1 
ATOM 669  C CG2 . VAL A 1 85  ? -47.181 -0.006  162.427 1.00 32.22  ? 85  VAL A CG2 1 
ATOM 670  N N   . VAL A 1 86  ? -50.187 -2.302  160.054 1.00 29.95  ? 86  VAL A N   1 
ATOM 671  C CA  . VAL A 1 86  ? -50.687 -3.221  158.990 1.00 29.95  ? 86  VAL A CA  1 
ATOM 672  C C   . VAL A 1 86  ? -51.827 -2.525  158.232 1.00 29.95  ? 86  VAL A C   1 
ATOM 673  O O   . VAL A 1 86  ? -51.854 -2.685  157.007 1.00 29.95  ? 86  VAL A O   1 
ATOM 674  C CB  . VAL A 1 86  ? -51.082 -4.590  159.575 1.00 29.95  ? 86  VAL A CB  1 
ATOM 675  C CG1 . VAL A 1 86  ? -51.957 -5.394  158.632 1.00 29.95  ? 86  VAL A CG1 1 
ATOM 676  C CG2 . VAL A 1 86  ? -49.860 -5.398  159.976 1.00 29.95  ? 86  VAL A CG2 1 
ATOM 677  N N   . SER A 1 87  ? -52.673 -1.725  158.902 1.00 29.99  ? 87  SER A N   1 
ATOM 678  C CA  . SER A 1 87  ? -53.847 -1.031  158.296 1.00 29.99  ? 87  SER A CA  1 
ATOM 679  C C   . SER A 1 87  ? -53.427 0.083   157.338 1.00 29.99  ? 87  SER A C   1 
ATOM 680  O O   . SER A 1 87  ? -54.163 0.315   156.381 1.00 29.99  ? 87  SER A O   1 
ATOM 681  C CB  . SER A 1 87  ? -54.765 -0.505  159.361 1.00 30.00  ? 87  SER A CB  1 
ATOM 682  O OG  . SER A 1 87  ? -54.300 0.722   159.897 1.00 30.00  ? 87  SER A OG  1 
ATOM 683  N N   . TYR A 1 88  ? -52.302 0.741   157.570 1.00 25.60  ? 88  TYR A N   1 
ATOM 684  C CA  . TYR A 1 88  ? -51.769 1.802   156.684 1.00 25.60  ? 88  TYR A CA  1 
ATOM 685  C C   . TYR A 1 88  ? -51.167 1.178   155.423 1.00 25.60  ? 88  TYR A C   1 
ATOM 686  O O   . TYR A 1 88  ? -51.115 1.842   154.372 1.00 25.60  ? 88  TYR A O   1 
ATOM 687  C CB  . TYR A 1 88  ? -50.735 2.625   157.453 1.00 25.60  ? 88  TYR A CB  1 
ATOM 688  C CG  . TYR A 1 88  ? -50.025 3.669   156.636 1.00 25.60  ? 88  TYR A CG  1 
ATOM 689  C CD1 . TYR A 1 88  ? -49.020 3.327   155.750 1.00 25.60  ? 88  TYR A CD1 1 
ATOM 690  C CD2 . TYR A 1 88  ? -50.363 5.002   156.753 1.00 25.60  ? 88  TYR A CD2 1 
ATOM 691  C CE1 . TYR A 1 88  ? -48.365 4.288   155.000 1.00 25.60  ? 88  TYR A CE1 1 
ATOM 692  C CE2 . TYR A 1 88  ? -49.717 5.975   156.016 1.00 25.60  ? 88  TYR A CE2 1 
ATOM 693  C CZ  . TYR A 1 88  ? -48.716 5.617   155.135 1.00 25.60  ? 88  TYR A CZ  1 
ATOM 694  O OH  . TYR A 1 88  ? -48.088 6.582   154.409 1.00 25.60  ? 88  TYR A OH  1 
ATOM 695  N N   . VAL A 1 89  ? -50.753 -0.076  155.489 1.00 23.98  ? 89  VAL A N   1 
ATOM 696  C CA  . VAL A 1 89  ? -50.054 -0.718  154.352 1.00 23.98  ? 89  VAL A CA  1 
ATOM 697  C C   . VAL A 1 89  ? -51.081 -1.367  153.429 1.00 23.98  ? 89  VAL A C   1 
ATOM 698  O O   . VAL A 1 89  ? -50.838 -1.369  152.208 1.00 23.98  ? 89  VAL A O   1 
ATOM 699  C CB  . VAL A 1 89  ? -49.002 -1.729  154.846 1.00 23.98  ? 89  VAL A CB  1 
ATOM 700  C CG1 . VAL A 1 89  ? -48.224 -2.321  153.682 1.00 23.98  ? 89  VAL A CG1 1 
ATOM 701  C CG2 . VAL A 1 89  ? -48.054 -1.114  155.858 1.00 23.98  ? 89  VAL A CG2 1 
ATOM 702  N N   . ASN A 1 90  ? -52.192 -1.875  153.958 1.00 24.74  ? 90  ASN A N   1 
ATOM 703  C CA  . ASN A 1 90  ? -53.187 -2.601  153.134 1.00 24.74  ? 90  ASN A CA  1 
ATOM 704  C C   . ASN A 1 90  ? -54.178 -1.583  152.575 1.00 24.74  ? 90  ASN A C   1 
ATOM 705  O O   . ASN A 1 90  ? -54.690 -1.827  151.474 1.00 24.74  ? 90  ASN A O   1 
ATOM 706  C CB  . ASN A 1 90  ? -53.848 -3.728  153.930 1.00 24.74  ? 90  ASN A CB  1 
ATOM 707  C CG  . ASN A 1 90  ? -52.864 -4.801  154.335 1.00 24.74  ? 90  ASN A CG  1 
ATOM 708  O OD1 . ASN A 1 90  ? -52.377 -5.552  153.498 1.00 24.74  ? 90  ASN A OD1 1 
ATOM 709  N ND2 . ASN A 1 90  ? -52.560 -4.876  155.618 1.00 24.74  ? 90  ASN A ND2 1 
ATOM 710  N N   . THR A 1 91  ? -54.400 -0.473  153.267 1.00 23.65  ? 91  THR A N   1 
ATOM 711  C CA  . THR A 1 91  ? -55.350 0.571   152.826 1.00 23.65  ? 91  THR A CA  1 
ATOM 712  C C   . THR A 1 91  ? -54.613 1.713   152.124 1.00 23.65  ? 91  THR A C   1 
ATOM 713  O O   . THR A 1 91  ? -54.966 1.982   150.977 1.00 23.65  ? 91  THR A O   1 
ATOM 714  C CB  . THR A 1 91  ? -56.183 1.094   154.002 1.00 23.65  ? 91  THR A CB  1 
ATOM 715  O OG1 . THR A 1 91  ? -56.724 -0.027  154.701 1.00 23.65  ? 91  THR A OG1 1 
ATOM 716  C CG2 . THR A 1 91  ? -57.294 2.022   153.567 1.00 23.65  ? 91  THR A CG2 1 
ATOM 717  N N   . ASN A 1 92  ? -53.653 2.376   152.764 1.00 22.32  ? 92  ASN A N   1 
ATOM 718  C CA  . ASN A 1 92  ? -52.989 3.573   152.180 1.00 22.32  ? 92  ASN A CA  1 
ATOM 719  C C   . ASN A 1 92  ? -51.952 3.217   151.088 1.00 22.32  ? 92  ASN A C   1 
ATOM 720  O O   . ASN A 1 92  ? -51.973 3.895   150.049 1.00 22.32  ? 92  ASN A O   1 
ATOM 721  C CB  . ASN A 1 92  ? -52.410 4.456   153.282 1.00 22.32  ? 92  ASN A CB  1 
ATOM 722  C CG  . ASN A 1 92  ? -53.461 5.272   154.005 1.00 22.32  ? 92  ASN A CG  1 
ATOM 723  O OD1 . ASN A 1 92  ? -54.627 5.272   153.625 1.00 22.32  ? 92  ASN A OD1 1 
ATOM 724  N ND2 . ASN A 1 92  ? -53.056 5.976   155.046 1.00 22.32  ? 92  ASN A ND2 1 
ATOM 725  N N   . MET A 1 93  ? -51.061 2.240   151.287 1.00 19.92  ? 93  MET A N   1 
ATOM 726  C CA  . MET A 1 93  ? -50.071 1.818   150.261 1.00 19.92  ? 93  MET A CA  1 
ATOM 727  C C   . MET A 1 93  ? -50.751 0.882   149.260 1.00 19.92  ? 93  MET A C   1 
ATOM 728  O O   . MET A 1 93  ? -50.161 0.624   148.212 1.00 19.92  ? 93  MET A O   1 
ATOM 729  C CB  . MET A 1 93  ? -48.878 1.101   150.897 1.00 19.92  ? 93  MET A CB  1 
ATOM 730  C CG  . MET A 1 93  ? -48.241 1.893   152.022 1.00 19.92  ? 93  MET A CG  1 
ATOM 731  S SD  . MET A 1 93  ? -46.606 1.285   152.489 1.00 19.92  ? 93  MET A SD  1 
ATOM 732  C CE  . MET A 1 93  ? -45.562 2.304   151.451 1.00 19.92  ? 93  MET A CE  1 
ATOM 733  N N   . GLY A 1 94  ? -51.949 0.414   149.572 1.00 15.70  ? 94  GLY A N   1 
ATOM 734  C CA  . GLY A 1 94  ? -52.686 -0.518  148.715 1.00 15.70  ? 94  GLY A CA  1 
ATOM 735  C C   . GLY A 1 94  ? -53.479 0.211   147.675 1.00 15.70  ? 94  GLY A C   1 
ATOM 736  O O   . GLY A 1 94  ? -53.641 -0.354  146.616 1.00 15.70  ? 94  GLY A O   1 
ATOM 737  N N   . LEU A 1 95  ? -53.968 1.407   147.980 1.00 14.34  ? 95  LEU A N   1 
ATOM 738  C CA  . LEU A 1 95  ? -54.755 2.233   147.025 1.00 14.34  ? 95  LEU A CA  1 
ATOM 739  C C   . LEU A 1 95  ? -53.837 2.753   145.930 1.00 14.34  ? 95  LEU A C   1 
ATOM 740  O O   . LEU A 1 95  ? -54.308 2.873   144.841 1.00 14.34  ? 95  LEU A O   1 
ATOM 741  C CB  . LEU A 1 95  ? -55.434 3.395   147.753 1.00 14.34  ? 95  LEU A CB  1 
ATOM 742  C CG  . LEU A 1 95  ? -56.135 4.409   146.850 1.00 14.34  ? 95  LEU A CG  1 
ATOM 743  C CD1 . LEU A 1 95  ? -57.192 3.737   145.987 1.00 14.34  ? 95  LEU A CD1 1 
ATOM 744  C CD2 . LEU A 1 95  ? -56.755 5.526   147.667 1.00 14.34  ? 95  LEU A CD2 1 
ATOM 745  N N   . LYS A 1 96  ? -52.579 3.070   146.221 1.00 14.59  ? 96  LYS A N   1 
ATOM 746  C CA  . LYS A 1 96  ? -51.593 3.476   145.198 1.00 14.59  ? 96  LYS A CA  1 
ATOM 747  C C   . LYS A 1 96  ? -51.244 2.262   144.340 1.00 14.59  ? 96  LYS A C   1 
ATOM 748  O O   . LYS A 1 96  ? -51.237 2.406   143.113 1.00 14.59  ? 96  LYS A O   1 
ATOM 749  C CB  . LYS A 1 96  ? -50.366 4.079   145.877 1.00 14.59  ? 96  LYS A CB  1 
ATOM 750  C CG  . LYS A 1 96  ? -50.590 5.425   146.544 1.00 14.59  ? 96  LYS A CG  1 
ATOM 751  C CD  . LYS A 1 96  ? -49.444 5.835   147.433 1.00 14.59  ? 96  LYS A CD  1 
ATOM 752  C CE  . LYS A 1 96  ? -49.421 7.319   147.720 1.00 14.59  ? 96  LYS A CE  1 
ATOM 753  N NZ  . LYS A 1 96  ? -49.023 8.094   146.524 1.00 14.59  ? 96  LYS A NZ  1 
ATOM 754  N N   . PHE A 1 97  ? -50.992 1.109   144.948 1.00 13.33  ? 97  PHE A N   1 
ATOM 755  C CA  . PHE A 1 97  ? -50.658 -0.132  144.212 1.00 13.33  ? 97  PHE A CA  1 
ATOM 756  C C   . PHE A 1 97  ? -51.813 -0.456  143.280 1.00 13.33  ? 97  PHE A C   1 
ATOM 757  O O   . PHE A 1 97  ? -51.568 -0.773  142.115 1.00 13.33  ? 97  PHE A O   1 
ATOM 758  C CB  . PHE A 1 97  ? -50.407 -1.289  145.174 1.00 30.00  ? 97  PHE A CB  1 
ATOM 759  C CG  . PHE A 1 97  ? -49.983 -2.583  144.531 1.00 30.00  ? 97  PHE A CG  1 
ATOM 760  C CD1 . PHE A 1 97  ? -48.939 -2.613  143.624 1.00 30.00  ? 97  PHE A CD1 1 
ATOM 761  C CD2 . PHE A 1 97  ? -50.611 -3.773  144.854 1.00 30.00  ? 97  PHE A CD2 1 
ATOM 762  C CE1 . PHE A 1 97  ? -48.544 -3.804  143.039 1.00 30.00  ? 97  PHE A CE1 1 
ATOM 763  C CE2 . PHE A 1 97  ? -50.213 -4.963  144.269 1.00 30.00  ? 97  PHE A CE2 1 
ATOM 764  C CZ  . PHE A 1 97  ? -49.179 -4.975  143.364 1.00 30.00  ? 97  PHE A CZ  1 
ATOM 765  N N   . ARG A 1 98  ? -53.040 -0.356  143.771 1.00 12.50  ? 98  ARG A N   1 
ATOM 766  C CA  . ARG A 1 98  ? -54.231 -0.702  142.972 1.00 12.50  ? 98  ARG A CA  1 
ATOM 767  C C   . ARG A 1 98  ? -54.255 0.186   141.734 1.00 12.50  ? 98  ARG A C   1 
ATOM 768  O O   . ARG A 1 98  ? -54.490 -0.348  140.645 1.00 12.50  ? 98  ARG A O   1 
ATOM 769  C CB  . ARG A 1 98  ? -55.484 -0.553  143.831 1.00 12.50  ? 98  ARG A CB  1 
ATOM 770  C CG  . ARG A 1 98  ? -55.622 -1.620  144.903 1.00 12.50  ? 98  ARG A CG  1 
ATOM 771  C CD  . ARG A 1 98  ? -56.577 -1.170  145.983 1.00 12.50  ? 98  ARG A CD  1 
ATOM 772  N NE  . ARG A 1 98  ? -57.818 -0.687  145.405 1.00 12.50  ? 98  ARG A NE  1 
ATOM 773  C CZ  . ARG A 1 98  ? -58.644 0.168   145.992 1.00 12.50  ? 98  ARG A CZ  1 
ATOM 774  N NH1 . ARG A 1 98  ? -58.364 0.659   147.186 1.00 12.50  ? 98  ARG A NH1 1 
ATOM 775  N NH2 . ARG A 1 98  ? -59.747 0.544   145.374 1.00 12.50  ? 98  ARG A NH2 1 
ATOM 776  N N   . GLN A 1 99  ? -53.964 1.463   141.898 1.00 12.13  ? 99  GLN A N   1 
ATOM 777  C CA  . GLN A 1 99  ? -54.011 2.433   140.781 1.00 12.13  ? 99  GLN A CA  1 
ATOM 778  C C   . GLN A 1 99  ? -53.000 2.059   139.703 1.00 12.13  ? 99  GLN A C   1 
ATOM 779  O O   . GLN A 1 99  ? -53.373 2.081   138.527 1.00 12.13  ? 99  GLN A O   1 
ATOM 780  C CB  . GLN A 1 99  ? -53.703 3.826   141.317 1.00 12.13  ? 99  GLN A CB  1 
ATOM 781  C CG  . GLN A 1 99  ? -54.205 4.952   140.429 1.00 12.13  ? 99  GLN A CG  1 
ATOM 782  C CD  . GLN A 1 99  ? -54.637 6.150   141.237 1.00 12.13  ? 99  GLN A CD  1 
ATOM 783  O OE1 . GLN A 1 99  ? -54.407 6.227   142.441 1.00 12.13  ? 99  GLN A OE1 1 
ATOM 784  N NE2 . GLN A 1 99  ? -55.265 7.107   140.574 1.00 12.13  ? 99  GLN A NE2 1 
ATOM 785  N N   . LEU A 1 100 ? -51.770 1.745   140.083 1.00 11.88  ? 100 LEU A N   1 
ATOM 786  C CA  . LEU A 1 100 ? -50.689 1.419   139.123 1.00 11.88  ? 100 LEU A CA  1 
ATOM 787  C C   . LEU A 1 100 ? -50.987 0.076   138.465 1.00 11.88  ? 100 LEU A C   1 
ATOM 788  O O   . LEU A 1 100 ? -50.838 -0.019  137.242 1.00 11.88  ? 100 LEU A O   1 
ATOM 789  C CB  . LEU A 1 100 ? -49.352 1.377   139.856 1.00 11.88  ? 100 LEU A CB  1 
ATOM 790  C CG  . LEU A 1 100 ? -48.128 1.253   138.955 1.00 11.88  ? 100 LEU A CG  1 
ATOM 791  C CD1 . LEU A 1 100 ? -48.022 2.450   138.029 1.00 11.88  ? 100 LEU A CD1 1 
ATOM 792  C CD2 . LEU A 1 100 ? -46.864 1.103   139.780 1.00 11.88  ? 100 LEU A CD2 1 
ATOM 793  N N   . LEU A 1 101 ? -51.402 -0.917  139.241 1.00 12.18  ? 101 LEU A N   1 
ATOM 794  C CA  . LEU A 1 101 ? -51.710 -2.261  138.704 1.00 12.18  ? 101 LEU A CA  1 
ATOM 795  C C   . LEU A 1 101 ? -52.804 -2.111  137.653 1.00 12.18  ? 101 LEU A C   1 
ATOM 796  O O   . LEU A 1 101 ? -52.687 -2.742  136.603 1.00 12.18  ? 101 LEU A O   1 
ATOM 797  C CB  . LEU A 1 101 ? -52.162 -3.183  139.835 1.00 12.18  ? 101 LEU A CB  1 
ATOM 798  C CG  . LEU A 1 101 ? -51.101 -4.103  140.429 1.00 12.18  ? 101 LEU A CG  1 
ATOM 799  C CD1 . LEU A 1 101 ? -51.729 -5.066  141.419 1.00 12.18  ? 101 LEU A CD1 1 
ATOM 800  C CD2 . LEU A 1 101 ? -50.372 -4.870  139.341 1.00 12.18  ? 101 LEU A CD2 1 
ATOM 801  N N   . TRP A 1 102 ? -53.819 -1.298  137.918 1.00 10.50  ? 102 TRP A N   1 
ATOM 802  C CA  . TRP A 1 102 ? -54.947 -1.107  136.977 1.00 10.50  ? 102 TRP A CA  1 
ATOM 803  C C   . TRP A 1 102 ? -54.424 -0.479  135.694 1.00 10.50  ? 102 TRP A C   1 
ATOM 804  O O   . TRP A 1 102 ? -54.721 -1.016  134.629 1.00 10.50  ? 102 TRP A O   1 
ATOM 805  C CB  . TRP A 1 102 ? -56.044 -0.255  137.607 1.00 10.50  ? 102 TRP A CB  1 
ATOM 806  C CG  . TRP A 1 102 ? -57.158 0.091   136.674 1.00 10.50  ? 102 TRP A CG  1 
ATOM 807  C CD1 . TRP A 1 102 ? -58.312 -0.605  136.472 1.00 10.50  ? 102 TRP A CD1 1 
ATOM 808  C CD2 . TRP A 1 102 ? -57.229 1.240   135.813 1.00 10.50  ? 102 TRP A CD2 1 
ATOM 809  N NE1 . TRP A 1 102 ? -59.091 0.026   135.544 1.00 10.50  ? 102 TRP A NE1 1 
ATOM 810  C CE2 . TRP A 1 102 ? -58.453 1.161   135.120 1.00 10.50  ? 102 TRP A CE2 1 
ATOM 811  C CE3 . TRP A 1 102 ? -56.377 2.318   135.560 1.00 10.50  ? 102 TRP A CE3 1 
ATOM 812  C CZ2 . TRP A 1 102 ? -58.843 2.121   134.194 1.00 10.50  ? 102 TRP A CZ2 1 
ATOM 813  C CZ3 . TRP A 1 102 ? -56.765 3.268   134.643 1.00 10.50  ? 102 TRP A CZ3 1 
ATOM 814  C CH2 . TRP A 1 102 ? -57.981 3.169   133.970 1.00 10.50  ? 102 TRP A CH2 1 
ATOM 815  N N   . PHE A 1 103 ? -53.651 0.596   135.783 1.00 10.15  ? 103 PHE A N   1 
ATOM 816  C CA  . PHE A 1 103 ? -53.178 1.325   134.587 1.00 10.15  ? 103 PHE A CA  1 
ATOM 817  C C   . PHE A 1 103 ? -52.381 0.383   133.698 1.00 10.15  ? 103 PHE A C   1 
ATOM 818  O O   . PHE A 1 103 ? -52.722 0.276   132.518 1.00 10.15  ? 103 PHE A O   1 
ATOM 819  C CB  . PHE A 1 103 ? -52.319 2.522   134.980 1.00 10.15  ? 103 PHE A CB  1 
ATOM 820  C CG  . PHE A 1 103 ? -51.704 3.264   133.826 1.00 10.15  ? 103 PHE A CG  1 
ATOM 821  C CD1 . PHE A 1 103 ? -52.426 4.216   133.129 1.00 10.15  ? 103 PHE A CD1 1 
ATOM 822  C CD2 . PHE A 1 103 ? -50.399 3.012   133.441 1.00 10.15  ? 103 PHE A CD2 1 
ATOM 823  C CE1 . PHE A 1 103 ? -51.857 4.897   132.067 1.00 10.15  ? 103 PHE A CE1 1 
ATOM 824  C CE2 . PHE A 1 103 ? -49.830 3.696   132.379 1.00 10.15  ? 103 PHE A CE2 1 
ATOM 825  C CZ  . PHE A 1 103 ? -50.561 4.638   131.695 1.00 10.15  ? 103 PHE A CZ  1 
ATOM 826  N N   . HIS A 1 104 ? -51.380 -0.302  134.233 1.00 11.33  ? 104 HIS A N   1 
ATOM 827  C CA  . HIS A 1 104 ? -50.476 -1.157  133.426 1.00 11.33  ? 104 HIS A CA  1 
ATOM 828  C C   . HIS A 1 104 ? -51.212 -2.391  132.913 1.00 11.33  ? 104 HIS A C   1 
ATOM 829  O O   . HIS A 1 104 ? -51.105 -2.667  131.719 1.00 11.33  ? 104 HIS A O   1 
ATOM 830  C CB  . HIS A 1 104 ? -49.231 -1.501  134.237 1.00 11.33  ? 104 HIS A CB  1 
ATOM 831  C CG  . HIS A 1 104 ? -48.355 -0.326  134.495 1.00 11.33  ? 104 HIS A CG  1 
ATOM 832  N ND1 . HIS A 1 104 ? -48.055 0.582   133.509 1.00 11.33  ? 104 HIS A ND1 1 
ATOM 833  C CD2 . HIS A 1 104 ? -47.714 0.090   135.605 1.00 11.33  ? 104 HIS A CD2 1 
ATOM 834  C CE1 . HIS A 1 104 ? -47.269 1.514   133.999 1.00 11.33  ? 104 HIS A CE1 1 
ATOM 835  N NE2 . HIS A 1 104 ? -47.044 1.235   135.281 1.00 11.33  ? 104 HIS A NE2 1 
ATOM 836  N N   . ILE A 1 105 ? -51.941 -3.099  133.767 1.00 11.90  ? 105 ILE A N   1 
ATOM 837  C CA  . ILE A 1 105 ? -52.672 -4.331  133.359 1.00 11.90  ? 105 ILE A CA  1 
ATOM 838  C C   . ILE A 1 105 ? -53.663 -3.931  132.276 1.00 11.90  ? 105 ILE A C   1 
ATOM 839  O O   . ILE A 1 105 ? -53.852 -4.718  131.350 1.00 11.90  ? 105 ILE A O   1 
ATOM 840  C CB  . ILE A 1 105 ? -53.370 -5.005  134.551 1.00 11.90  ? 105 ILE A CB  1 
ATOM 841  C CG1 . ILE A 1 105 ? -52.360 -5.567  135.553 1.00 11.90  ? 105 ILE A CG1 1 
ATOM 842  C CG2 . ILE A 1 105 ? -54.333 -6.075  134.072 1.00 11.90  ? 105 ILE A CG2 1 
ATOM 843  C CD1 . ILE A 1 105 ? -52.985 -6.077  136.827 1.00 11.90  ? 105 ILE A CD1 1 
ATOM 844  N N   . SER A 1 106 ? -54.252 -2.745  132.370 1.00 11.20  ? 106 SER A N   1 
ATOM 845  C CA  . SER A 1 106 ? -55.273 -2.267  131.410 1.00 11.20  ? 106 SER A CA  1 
ATOM 846  C C   . SER A 1 106 ? -54.610 -1.792  130.127 1.00 11.20  ? 106 SER A C   1 
ATOM 847  O O   . SER A 1 106 ? -55.235 -1.900  129.088 1.00 11.20  ? 106 SER A O   1 
ATOM 848  C CB  . SER A 1 106 ? -56.090 -1.183  132.015 1.00 11.20  ? 106 SER A CB  1 
ATOM 849  O OG  . SER A 1 106 ? -56.807 -1.663  133.137 1.00 11.20  ? 106 SER A OG  1 
ATOM 850  N N   . CYS A 1 107 ? -53.407 -1.246  130.202 1.00 10.87  ? 107 CYS A N   1 
ATOM 851  C CA  . CYS A 1 107 ? -52.663 -0.776  129.014 1.00 10.87  ? 107 CYS A CA  1 
ATOM 852  C C   . CYS A 1 107 ? -52.164 -2.000  128.261 1.00 10.87  ? 107 CYS A C   1 
ATOM 853  O O   . CYS A 1 107 ? -52.032 -1.920  127.040 1.00 10.87  ? 107 CYS A O   1 
ATOM 854  C CB  . CYS A 1 107 ? -51.509 0.130   129.405 1.00 10.87  ? 107 CYS A CB  1 
ATOM 855  S SG  . CYS A 1 107 ? -52.023 1.812   129.830 1.00 10.87  ? 107 CYS A SG  1 
ATOM 856  N N   . LEU A 1 108 ? -51.905 -3.092  128.970 1.00 12.16  ? 108 LEU A N   1 
ATOM 857  C CA  . LEU A 1 108 ? -51.432 -4.344  128.341 1.00 12.16  ? 108 LEU A CA  1 
ATOM 858  C C   . LEU A 1 108 ? -52.623 -4.994  127.641 1.00 12.16  ? 108 LEU A C   1 
ATOM 859  O O   . LEU A 1 108 ? -52.427 -5.473  126.522 1.00 12.16  ? 108 LEU A O   1 
ATOM 860  C CB  . LEU A 1 108 ? -50.820 -5.269  129.391 1.00 12.16  ? 108 LEU A CB  1 
ATOM 861  C CG  . LEU A 1 108 ? -49.449 -4.861  129.921 1.00 12.16  ? 108 LEU A CG  1 
ATOM 862  C CD1 . LEU A 1 108 ? -49.000 -5.804  131.021 1.00 12.16  ? 108 LEU A CD1 1 
ATOM 863  C CD2 . LEU A 1 108 ? -48.422 -4.822  128.804 1.00 12.16  ? 108 LEU A CD2 1 
ATOM 864  N N   . THR A 1 109 ? -53.805 -5.024  128.258 1.00 13.02  ? 109 THR A N   1 
ATOM 865  C CA  . THR A 1 109 ? -54.936 -5.695  127.613 1.00 13.02  ? 109 THR A CA  1 
ATOM 866  C C   . THR A 1 109 ? -55.554 -4.860  126.495 1.00 13.02  ? 109 THR A C   1 
ATOM 867  O O   . THR A 1 109 ? -55.663 -5.307  125.347 1.00 13.02  ? 109 THR A O   1 
ATOM 868  C CB  . THR A 1 109 ? -55.994 -6.038  128.664 1.00 13.02  ? 109 THR A CB  1 
ATOM 869  O OG1 . THR A 1 109 ? -55.372 -6.687  129.779 1.00 13.02  ? 109 THR A OG1 1 
ATOM 870  C CG2 . THR A 1 109 ? -57.058 -6.955  128.077 1.00 13.02  ? 109 THR A CG2 1 
ATOM 871  N N   . PHE A 1 110 ? -55.974 -3.641  126.824 1.00 13.15  ? 110 PHE A N   1 
ATOM 872  C CA  . PHE A 1 110 ? -56.683 -2.754  125.907 1.00 13.15  ? 110 PHE A CA  1 
ATOM 873  C C   . PHE A 1 110 ? -55.766 -1.979  124.969 1.00 13.15  ? 110 PHE A C   1 
ATOM 874  O O   . PHE A 1 110 ? -56.180 -1.637  123.856 1.00 13.15  ? 110 PHE A O   1 
ATOM 875  C CB  . PHE A 1 110 ? -57.589 -1.849  126.734 1.00 13.15  ? 110 PHE A CB  1 
ATOM 876  C CG  . PHE A 1 110 ? -58.481 -2.628  127.658 1.00 13.15  ? 110 PHE A CG  1 
ATOM 877  C CD1 . PHE A 1 110 ? -59.519 -3.386  127.148 1.00 13.15  ? 110 PHE A CD1 1 
ATOM 878  C CD2 . PHE A 1 110 ? -58.305 -2.576  129.028 1.00 13.15  ? 110 PHE A CD2 1 
ATOM 879  C CE1 . PHE A 1 110 ? -60.355 -4.097  127.985 1.00 13.15  ? 110 PHE A CE1 1 
ATOM 880  C CE2 . PHE A 1 110 ? -59.147 -3.275  129.872 1.00 13.15  ? 110 PHE A CE2 1 
ATOM 881  C CZ  . PHE A 1 110 ? -60.163 -4.048  129.348 1.00 13.15  ? 110 PHE A CZ  1 
ATOM 882  N N   . GLY A 1 111 ? -54.543 -1.687  125.380 1.00 11.71  ? 111 GLY A N   1 
ATOM 883  C CA  . GLY A 1 111 ? -53.730 -0.658  124.761 1.00 11.71  ? 111 GLY A CA  1 
ATOM 884  C C   . GLY A 1 111 ? -53.770 0.672   125.494 1.00 11.71  ? 111 GLY A C   1 
ATOM 885  O O   . GLY A 1 111 ? -54.782 1.075   126.079 1.00 11.71  ? 111 GLY A O   1 
ATOM 886  N N   . ARG A 1 112 ? -52.575 1.254   125.649 1.00 12.13  ? 112 ARG A N   1 
ATOM 887  C CA  . ARG A 1 112 ? -52.374 2.490   126.444 1.00 12.13  ? 112 ARG A CA  1 
ATOM 888  C C   . ARG A 1 112 ? -53.157 3.653   125.846 1.00 12.13  ? 112 ARG A C   1 
ATOM 889  O O   . ARG A 1 112 ? -53.707 4.429   126.632 1.00 12.13  ? 112 ARG A O   1 
ATOM 890  C CB  . ARG A 1 112 ? -50.865 2.743   126.481 1.00 12.13  ? 112 ARG A CB  1 
ATOM 891  C CG  . ARG A 1 112 ? -50.417 4.004   127.200 1.00 12.13  ? 112 ARG A CG  1 
ATOM 892  C CD  . ARG A 1 112 ? -49.027 4.325   126.690 1.00 12.13  ? 112 ARG A CD  1 
ATOM 893  N NE  . ARG A 1 112 ? -49.085 4.837   125.328 1.00 12.13  ? 112 ARG A NE  1 
ATOM 894  C CZ  . ARG A 1 112 ? -49.369 6.092   124.998 1.00 12.13  ? 112 ARG A CZ  1 
ATOM 895  N NH1 . ARG A 1 112 ? -49.627 6.991   125.932 1.00 12.13  ? 112 ARG A NH1 1 
ATOM 896  N NH2 . ARG A 1 112 ? -49.398 6.444   123.726 1.00 12.13  ? 112 ARG A NH2 1 
ATOM 897  N N   . GLU A 1 113 ? -53.188 3.785   124.521 1.00 12.80  ? 113 GLU A N   1 
ATOM 898  C CA  . GLU A 1 113 ? -54.010 4.835   123.872 1.00 12.80  ? 113 GLU A CA  1 
ATOM 899  C C   . GLU A 1 113 ? -55.440 4.636   124.372 1.00 12.80  ? 113 GLU A C   1 
ATOM 900  O O   . GLU A 1 113 ? -55.998 5.601   124.920 1.00 12.80  ? 113 GLU A O   1 
ATOM 901  C CB  . GLU A 1 113 ? -53.915 4.741   122.350 1.00 12.80  ? 113 GLU A CB  1 
ATOM 902  C CG  . GLU A 1 113 ? -52.540 5.087   121.809 1.00 12.80  ? 113 GLU A CG  1 
ATOM 903  C CD  . GLU A 1 113 ? -52.162 6.555   121.916 1.00 12.80  ? 113 GLU A CD  1 
ATOM 904  O OE1 . GLU A 1 113 ? -52.958 7.332   122.479 1.00 12.80  ? 113 GLU A OE1 1 
ATOM 905  O OE2 . GLU A 1 113 ? -51.073 6.917   121.430 1.00 12.80  ? 113 GLU A OE2 1 
ATOM 906  N N   . THR A 1 114 ? -55.970 3.415   124.280 1.00 11.56  ? 114 THR A N   1 
ATOM 907  C CA  . THR A 1 114 ? -57.349 3.085   124.728 1.00 11.56  ? 114 THR A CA  1 
ATOM 908  C C   . THR A 1 114 ? -57.503 3.435   126.209 1.00 11.56  ? 114 THR A C   1 
ATOM 909  O O   . THR A 1 114 ? -58.511 4.071   126.546 1.00 11.56  ? 114 THR A O   1 
ATOM 910  C CB  . THR A 1 114 ? -57.673 1.606   124.486 1.00 11.56  ? 114 THR A CB  1 
ATOM 911  O OG1 . THR A 1 114 ? -57.579 1.362   123.082 1.00 11.56  ? 114 THR A OG1 1 
ATOM 912  C CG2 . THR A 1 114 ? -59.046 1.213   124.983 1.00 11.56  ? 114 THR A CG2 1 
ATOM 913  N N   . VAL A 1 115 ? -56.542 3.051   127.053 1.00 10.90  ? 115 VAL A N   1 
ATOM 914  C CA  . VAL A 1 115 ? -56.611 3.294   128.524 1.00 10.90  ? 115 VAL A CA  1 
ATOM 915  C C   . VAL A 1 115 ? -56.728 4.800   128.774 1.00 10.90  ? 115 VAL A C   1 
ATOM 916  O O   . VAL A 1 115 ? -57.601 5.186   129.568 1.00 10.90  ? 115 VAL A O   1 
ATOM 917  C CB  . VAL A 1 115 ? -55.390 2.696   129.249 1.00 10.90  ? 115 VAL A CB  1 
ATOM 918  C CG1 . VAL A 1 115 ? -55.179 3.321   130.619 1.00 10.90  ? 115 VAL A CG1 1 
ATOM 919  C CG2 . VAL A 1 115 ? -55.485 1.183   129.361 1.00 10.90  ? 115 VAL A CG2 1 
ATOM 920  N N   . ILE A 1 116 ? -55.915 5.622   128.107 1.00 11.66  ? 116 ILE A N   1 
ATOM 921  C CA  . ILE A 1 116 ? -55.891 7.101   128.324 1.00 11.66  ? 116 ILE A CA  1 
ATOM 922  C C   . ILE A 1 116 ? -57.183 7.711   127.771 1.00 11.66  ? 116 ILE A C   1 
ATOM 923  O O   . ILE A 1 116 ? -57.670 8.696   128.368 1.00 11.66  ? 116 ILE A O   1 
ATOM 924  C CB  . ILE A 1 116 ? -54.625 7.707   127.688 1.00 30.00  ? 116 ILE A CB  1 
ATOM 925  C CG1 . ILE A 1 116 ? -53.356 7.122   128.314 1.00 30.00  ? 116 ILE A CG1 1 
ATOM 926  C CG2 . ILE A 1 116 ? -54.646 9.223   127.782 1.00 30.00  ? 116 ILE A CG2 1 
ATOM 927  C CD1 . ILE A 1 116 ? -52.103 7.367   127.511 1.00 30.00  ? 116 ILE A CD1 1 
ATOM 928  N N   . GLU A 1 117 ? -57.724 7.154   126.685 1.00 11.85  ? 117 GLU A N   1 
ATOM 929  C CA  . GLU A 1 117 ? -58.994 7.634   126.080 1.00 11.85  ? 117 GLU A CA  1 
ATOM 930  C C   . GLU A 1 117 ? -60.127 7.339   127.062 1.00 11.85  ? 117 GLU A C   1 
ATOM 931  O O   . GLU A 1 117 ? -61.068 8.163   127.145 1.00 11.85  ? 117 GLU A O   1 
ATOM 932  C CB  . GLU A 1 117 ? -59.223 6.947   124.735 1.00 11.85  ? 117 GLU A CB  1 
ATOM 933  C CG  . GLU A 1 117 ? -58.169 7.288   123.698 1.00 11.85  ? 117 GLU A CG  1 
ATOM 934  C CD  . GLU A 1 117 ? -57.950 6.220   122.639 1.00 11.85  ? 117 GLU A CD  1 
ATOM 935  O OE1 . GLU A 1 117 ? -58.815 5.331   122.509 1.00 11.85  ? 117 GLU A OE1 1 
ATOM 936  O OE2 . GLU A 1 117 ? -56.913 6.278   121.952 1.00 11.85  ? 117 GLU A OE2 1 
ATOM 937  N N   . TYR A 1 118 ? -60.035 6.223   127.790 1.00 10.48  ? 118 TYR A N   1 
ATOM 938  C CA  . TYR A 1 118 ? -61.067 5.802   128.771 1.00 10.48  ? 118 TYR A CA  1 
ATOM 939  C C   . TYR A 1 118 ? -60.998 6.719   129.993 1.00 10.48  ? 118 TYR A C   1 
ATOM 940  O O   . TYR A 1 118 ? -62.029 6.864   130.684 1.00 10.48  ? 118 TYR A O   1 
ATOM 941  C CB  . TYR A 1 118 ? -60.858 4.331   129.140 1.00 10.48  ? 118 TYR A CB  1 
ATOM 942  C CG  . TYR A 1 118 ? -61.707 3.831   130.281 1.00 10.48  ? 118 TYR A CG  1 
ATOM 943  C CD1 . TYR A 1 118 ? -62.969 3.311   130.055 1.00 10.48  ? 118 TYR A CD1 1 
ATOM 944  C CD2 . TYR A 1 118 ? -61.246 3.868   131.586 1.00 10.48  ? 118 TYR A CD2 1 
ATOM 945  C CE1 . TYR A 1 118 ? -63.756 2.845   131.095 1.00 10.48  ? 118 TYR A CE1 1 
ATOM 946  C CE2 . TYR A 1 118 ? -62.019 3.408   132.639 1.00 10.48  ? 118 TYR A CE2 1 
ATOM 947  C CZ  . TYR A 1 118 ? -63.280 2.893   132.393 1.00 10.48  ? 118 TYR A CZ  1 
ATOM 948  O OH  . TYR A 1 118 ? -64.050 2.436   133.422 1.00 10.48  ? 118 TYR A OH  1 
ATOM 949  N N   . LEU A 1 119 ? -59.827 7.306   130.267 1.00 10.77  ? 119 LEU A N   1 
ATOM 950  C CA  . LEU A 1 119 ? -59.645 8.169   131.458 1.00 10.77  ? 119 LEU A CA  1 
ATOM 951  C C   . LEU A 1 119 ? -60.340 9.506   131.209 1.00 10.77  ? 119 LEU A C   1 
ATOM 952  O O   . LEU A 1 119 ? -60.930 10.024  132.132 1.00 10.77  ? 119 LEU A O   1 
ATOM 953  C CB  . LEU A 1 119 ? -58.145 8.321   131.719 1.00 10.77  ? 119 LEU A CB  1 
ATOM 954  C CG  . LEU A 1 119 ? -57.438 7.099   132.297 1.00 10.77  ? 119 LEU A CG  1 
ATOM 955  C CD1 . LEU A 1 119 ? -55.931 7.249   132.183 1.00 10.77  ? 119 LEU A CD1 1 
ATOM 956  C CD2 . LEU A 1 119 ? -57.837 6.867   133.740 1.00 10.77  ? 119 LEU A CD2 1 
ATOM 957  N N   . VAL A 1 120 ? -60.287 10.016  129.990 1.00 10.53  ? 120 VAL A N   1 
ATOM 958  C CA  . VAL A 1 120 ? -60.981 11.291  129.632 1.00 10.53  ? 120 VAL A CA  1 
ATOM 959  C C   . VAL A 1 120 ? -62.498 11.089  129.659 1.00 10.53  ? 120 VAL A C   1 
ATOM 960  O O   . VAL A 1 120 ? -63.204 11.951  130.229 1.00 10.53  ? 120 VAL A O   1 
ATOM 961  C CB  . VAL A 1 120 ? -60.529 11.807  128.260 1.00 10.53  ? 120 VAL A CB  1 
ATOM 962  C CG1 . VAL A 1 120 ? -61.365 12.989  127.808 1.00 10.53  ? 120 VAL A CG1 1 
ATOM 963  C CG2 . VAL A 1 120 ? -59.052 12.156  128.256 1.00 10.53  ? 120 VAL A CG2 1 
ATOM 964  N N   . SER A 1 121 ? -63.005 10.003  129.087 1.00 10.02  ? 121 SER A N   1 
ATOM 965  C CA  . SER A 1 121 ? -64.464 9.752   128.981 1.00 10.02  ? 121 SER A CA  1 
ATOM 966  C C   . SER A 1 121 ? -65.098 9.525   130.352 1.00 10.02  ? 121 SER A C   1 
ATOM 967  O O   . SER A 1 121 ? -66.217 10.021  130.582 1.00 10.02  ? 121 SER A O   1 
ATOM 968  C CB  . SER A 1 121 ? -64.705 8.591   128.090 1.00 10.02  ? 121 SER A CB  1 
ATOM 969  O OG  . SER A 1 121 ? -64.126 8.815   126.815 1.00 10.02  ? 121 SER A OG  1 
ATOM 970  N N   . PHE A 1 122 ? -64.445 8.768   131.224 1.00 10.34  ? 122 PHE A N   1 
ATOM 971  C CA  . PHE A 1 122 ? -64.962 8.489   132.580 1.00 10.34  ? 122 PHE A CA  1 
ATOM 972  C C   . PHE A 1 122 ? -64.989 9.821   133.290 1.00 10.34  ? 122 PHE A C   1 
ATOM 973  O O   . PHE A 1 122 ? -65.886 10.049  134.075 1.00 10.34  ? 122 PHE A O   1 
ATOM 974  C CB  . PHE A 1 122 ? -64.104 7.495   133.354 1.00 10.34  ? 122 PHE A CB  1 
ATOM 975  C CG  . PHE A 1 122 ? -64.745 7.016   134.627 1.00 10.34  ? 122 PHE A CG  1 
ATOM 976  C CD1 . PHE A 1 122 ? -64.796 7.832   135.743 1.00 10.34  ? 122 PHE A CD1 1 
ATOM 977  C CD2 . PHE A 1 122 ? -65.319 5.760   134.702 1.00 10.34  ? 122 PHE A CD2 1 
ATOM 978  C CE1 . PHE A 1 122 ? -65.399 7.397   136.910 1.00 10.34  ? 122 PHE A CE1 1 
ATOM 979  C CE2 . PHE A 1 122 ? -65.921 5.326   135.871 1.00 10.34  ? 122 PHE A CE2 1 
ATOM 980  C CZ  . PHE A 1 122 ? -65.959 6.146   136.973 1.00 10.34  ? 122 PHE A CZ  1 
ATOM 981  N N   . GLY A 1 123 ? -64.007 10.663  133.015 1.00 10.29  ? 123 GLY A N   1 
ATOM 982  C CA  . GLY A 1 123 ? -63.978 12.009  133.597 1.00 10.29  ? 123 GLY A CA  1 
ATOM 983  C C   . GLY A 1 123 ? -65.219 12.751  133.183 1.00 10.29  ? 123 GLY A C   1 
ATOM 984  O O   . GLY A 1 123 ? -65.956 13.183  134.063 1.00 10.29  ? 123 GLY A O   1 
ATOM 985  N N   . VAL A 1 124 ? -65.491 12.818  131.886 1.00 9.96   ? 124 VAL A N   1 
ATOM 986  C CA  . VAL A 1 124 ? -66.720 13.485  131.380 1.00 9.96   ? 124 VAL A CA  1 
ATOM 987  C C   . VAL A 1 124 ? -67.931 12.915  132.111 1.00 9.96   ? 124 VAL A C   1 
ATOM 988  O O   . VAL A 1 124 ? -68.755 13.716  132.521 1.00 9.96   ? 124 VAL A O   1 
ATOM 989  C CB  . VAL A 1 124 ? -66.881 13.315  129.863 1.00 9.96   ? 124 VAL A CB  1 
ATOM 990  C CG1 . VAL A 1 124 ? -68.246 13.781  129.394 1.00 9.96   ? 124 VAL A CG1 1 
ATOM 991  C CG2 . VAL A 1 124 ? -65.778 14.023  129.101 1.00 9.96   ? 124 VAL A CG2 1 
ATOM 992  N N   . TRP A 1 125 ? -68.022 11.598  132.289 1.00 10.27  ? 125 TRP A N   1 
ATOM 993  C CA  . TRP A 1 125 ? -69.203 10.934  132.907 1.00 10.27  ? 125 TRP A CA  1 
ATOM 994  C C   . TRP A 1 125 ? -69.358 11.304  134.374 1.00 10.27  ? 125 TRP A C   1 
ATOM 995  O O   . TRP A 1 125 ? -70.482 11.581  134.783 1.00 10.27  ? 125 TRP A O   1 
ATOM 996  C CB  . TRP A 1 125 ? -69.063 9.423   132.767 1.00 10.27  ? 125 TRP A CB  1 
ATOM 997  C CG  . TRP A 1 125 ? -70.169 8.620   133.372 1.00 10.27  ? 125 TRP A CG  1 
ATOM 998  C CD1 . TRP A 1 125 ? -71.316 8.214   132.761 1.00 10.27  ? 125 TRP A CD1 1 
ATOM 999  C CD2 . TRP A 1 125 ? -70.209 8.078   134.702 1.00 10.27  ? 125 TRP A CD2 1 
ATOM 1000 N NE1 . TRP A 1 125 ? -72.075 7.474   133.623 1.00 10.27  ? 125 TRP A NE1 1 
ATOM 1001 C CE2 . TRP A 1 125 ? -71.423 7.373   134.821 1.00 10.27  ? 125 TRP A CE2 1 
ATOM 1002 C CE3 . TRP A 1 125 ? -69.347 8.129   135.801 1.00 10.27  ? 125 TRP A CE3 1 
ATOM 1003 C CZ2 . TRP A 1 125 ? -71.795 6.727   135.994 1.00 10.27  ? 125 TRP A CZ2 1 
ATOM 1004 C CZ3 . TRP A 1 125 ? -69.715 7.488   136.962 1.00 10.27  ? 125 TRP A CZ3 1 
ATOM 1005 C CH2 . TRP A 1 125 ? -70.923 6.798   137.055 1.00 10.27  ? 125 TRP A CH2 1 
ATOM 1006 N N   . ILE A 1 126 ? -68.281 11.276  135.142 1.00 10.78  ? 126 ILE A N   1 
ATOM 1007 C CA  . ILE A 1 126 ? -68.333 11.540  136.602 1.00 10.78  ? 126 ILE A CA  1 
ATOM 1008 C C   . ILE A 1 126 ? -68.612 13.023  136.755 1.00 10.78  ? 126 ILE A C   1 
ATOM 1009 O O   . ILE A 1 126 ? -69.300 13.386  137.723 1.00 10.78  ? 126 ILE A O   1 
ATOM 1010 C CB  . ILE A 1 126 ? -67.039 11.096  137.304 1.00 10.78  ? 126 ILE A CB  1 
ATOM 1011 C CG1 . ILE A 1 126 ? -67.272 10.836  138.791 1.00 10.78  ? 126 ILE A CG1 1 
ATOM 1012 C CG2 . ILE A 1 126 ? -65.912 12.088  137.070 1.00 10.78  ? 126 ILE A CG2 1 
ATOM 1013 C CD1 . ILE A 1 126 ? -68.075 9.592   139.064 1.00 10.78  ? 126 ILE A CD1 1 
ATOM 1014 N N   . ARG A 1 127 ? -68.127 13.860  135.835 1.00 11.27  ? 127 ARG A N   1 
ATOM 1015 C CA  . ARG A 1 127 ? -68.514 15.267  135.920 1.00 11.27  ? 127 ARG A CA  1 
ATOM 1016 C C   . ARG A 1 127 ? -69.999 15.504  135.648 1.00 11.27  ? 127 ARG A C   1 
ATOM 1017 O O   . ARG A 1 127 ? -70.571 16.455  136.191 1.00 11.27  ? 127 ARG A O   1 
ATOM 1018 C CB  . ARG A 1 127 ? -67.674 16.102  134.954 1.00 11.27  ? 127 ARG A CB  1 
ATOM 1019 C CG  . ARG A 1 127 ? -66.257 16.351  135.433 1.00 11.27  ? 127 ARG A CG  1 
ATOM 1020 C CD  . ARG A 1 127 ? -65.592 17.456  134.633 1.00 11.27  ? 127 ARG A CD  1 
ATOM 1021 N NE  . ARG A 1 127 ? -65.684 17.223  133.198 1.00 11.27  ? 127 ARG A NE  1 
ATOM 1022 C CZ  . ARG A 1 127 ? -64.777 16.576  132.479 1.00 11.27  ? 127 ARG A CZ  1 
ATOM 1023 N NH1 . ARG A 1 127 ? -63.726 16.001  133.043 1.00 11.27  ? 127 ARG A NH1 1 
ATOM 1024 N NH2 . ARG A 1 127 ? -64.918 16.518  131.158 1.00 11.27  ? 127 ARG A NH2 1 
ATOM 1025 N N   . THR A 1 128 ? -70.638 14.684  134.824 1.00 11.83  ? 128 THR A N   1 
ATOM 1026 C CA  . THR A 1 128 ? -72.057 14.882  134.541 1.00 11.83  ? 128 THR A CA  1 
ATOM 1027 C C   . THR A 1 128 ? -72.888 14.841  135.827 1.00 11.83  ? 128 THR A C   1 
ATOM 1028 O O   . THR A 1 128 ? -72.742 13.904  136.625 1.00 11.83  ? 128 THR A O   1 
ATOM 1029 C CB  . THR A 1 128 ? -72.557 13.813  133.569 1.00 11.83  ? 128 THR A CB  1 
ATOM 1030 O OG1 . THR A 1 128 ? -71.774 13.852  132.370 1.00 11.83  ? 128 THR A OG1 1 
ATOM 1031 C CG2 . THR A 1 128 ? -74.020 14.049  133.218 1.00 11.83  ? 128 THR A CG2 1 
ATOM 1032 N N   . PRO A 1 129 ? -73.756 15.825  136.063 1.00 12.46  ? 129 PRO A N   1 
ATOM 1033 C CA  . PRO A 1 129 ? -74.647 15.794  137.237 1.00 12.46  ? 129 PRO A CA  1 
ATOM 1034 C C   . PRO A 1 129 ? -75.561 14.580  137.236 1.00 12.46  ? 129 PRO A C   1 
ATOM 1035 O O   . PRO A 1 129 ? -76.018 14.136  136.173 1.00 12.46  ? 129 PRO A O   1 
ATOM 1036 C CB  . PRO A 1 129 ? -75.453 17.096  137.103 1.00 12.46  ? 129 PRO A CB  1 
ATOM 1037 C CG  . PRO A 1 129 ? -74.568 17.997  136.333 1.00 12.46  ? 129 PRO A CG  1 
ATOM 1038 C CD  . PRO A 1 129 ? -73.886 17.101  135.336 1.00 12.46  ? 129 PRO A CD  1 
ATOM 1039 N N   . PRO A 1 130 ? -75.852 14.015  138.414 1.00 13.33  ? 130 PRO A N   1 
ATOM 1040 C CA  . PRO A 1 130 ? -76.599 12.746  138.472 1.00 13.33  ? 130 PRO A CA  1 
ATOM 1041 C C   . PRO A 1 130 ? -77.938 12.747  137.746 1.00 13.33  ? 130 PRO A C   1 
ATOM 1042 O O   . PRO A 1 130 ? -78.366 11.690  137.264 1.00 13.33  ? 130 PRO A O   1 
ATOM 1043 C CB  . PRO A 1 130 ? -76.802 12.543  139.980 1.00 13.33  ? 130 PRO A CB  1 
ATOM 1044 C CG  . PRO A 1 130 ? -75.630 13.186  140.595 1.00 13.33  ? 130 PRO A CG  1 
ATOM 1045 C CD  . PRO A 1 130 ? -75.378 14.413  139.752 1.00 13.33  ? 130 PRO A CD  1 
ATOM 1046 N N   . ALA A 1 131 ? -78.617 13.894  137.649 1.00 12.99  ? 131 ALA A N   1 
ATOM 1047 C CA  . ALA A 1 131 ? -79.879 13.952  136.918 1.00 12.99  ? 131 ALA A CA  1 
ATOM 1048 C C   . ALA A 1 131 ? -79.719 13.633  135.439 1.00 12.99  ? 131 ALA A C   1 
ATOM 1049 O O   . ALA A 1 131 ? -80.690 13.213  134.799 1.00 12.99  ? 131 ALA A O   1 
ATOM 1050 C CB  . ALA A 1 131 ? -80.512 15.334  137.080 1.00 12.99  ? 131 ALA A CB  1 
ATOM 1051 N N   . TYR A 1 132 ? -78.527 13.824  134.881 1.00 12.69  ? 132 TYR A N   1 
ATOM 1052 C CA  . TYR A 1 132 ? -78.275 13.592  133.468 1.00 12.69  ? 132 TYR A CA  1 
ATOM 1053 C C   . TYR A 1 132 ? -77.219 12.529  133.219 1.00 12.69  ? 132 TYR A C   1 
ATOM 1054 O O   . TYR A 1 132 ? -77.070 12.085  132.074 1.00 12.69  ? 132 TYR A O   1 
ATOM 1055 C CB  . TYR A 1 132 ? -77.868 14.903  132.777 1.00 12.69  ? 132 TYR A CB  1 
ATOM 1056 C CG  . TYR A 1 132 ? -78.898 15.998  132.947 1.00 12.69  ? 132 TYR A CG  1 
ATOM 1057 C CD1 . TYR A 1 132 ? -80.074 15.988  132.209 1.00 12.69  ? 132 TYR A CD1 1 
ATOM 1058 C CD2 . TYR A 1 132 ? -78.699 17.035  133.846 1.00 12.69  ? 132 TYR A CD2 1 
ATOM 1059 C CE1 . TYR A 1 132 ? -81.021 16.980  132.359 1.00 12.69  ? 132 TYR A CE1 1 
ATOM 1060 C CE2 . TYR A 1 132 ? -79.643 18.033  134.004 1.00 12.69  ? 132 TYR A CE2 1 
ATOM 1061 C CZ  . TYR A 1 132 ? -80.802 17.998  133.261 1.00 12.69  ? 132 TYR A CZ  1 
ATOM 1062 O OH  . TYR A 1 132 ? -81.749 18.984  133.419 1.00 12.69  ? 132 TYR A OH  1 
ATOM 1063 N N   . ARG A 1 133 ? -76.489 12.113  134.244 1.00 12.19  ? 133 ARG A N   1 
ATOM 1064 C CA  . ARG A 1 133 ? -75.487 11.067  134.116 1.00 12.19  ? 133 ARG A CA  1 
ATOM 1065 C C   . ARG A 1 133 ? -76.155 9.745   133.744 1.00 12.19  ? 133 ARG A C   1 
ATOM 1066 O O   . ARG A 1 133 ? -77.040 9.282   134.479 1.00 12.19  ? 133 ARG A O   1 
ATOM 1067 C CB  . ARG A 1 133 ? -74.735 10.929  135.435 1.00 12.19  ? 133 ARG A CB  1 
ATOM 1068 C CG  . ARG A 1 133 ? -73.497 10.062  135.378 1.00 12.19  ? 133 ARG A CG  1 
ATOM 1069 C CD  . ARG A 1 133 ? -72.904 9.901   136.765 1.00 12.19  ? 133 ARG A CD  1 
ATOM 1070 N NE  . ARG A 1 133 ? -72.546 11.182  137.358 1.00 12.19  ? 133 ARG A NE  1 
ATOM 1071 C CZ  . ARG A 1 133 ? -72.373 11.385  138.657 1.00 12.19  ? 133 ARG A CZ  1 
ATOM 1072 N NH1 . ARG A 1 133 ? -72.442 10.391  139.528 1.00 12.19  ? 133 ARG A NH1 1 
ATOM 1073 N NH2 . ARG A 1 133 ? -72.101 12.612  139.091 1.00 12.19  ? 133 ARG A NH2 1 
ATOM 1074 N N   . PRO A 1 134 ? -75.779 9.109   132.630 1.00 12.37  ? 134 PRO A N   1 
ATOM 1075 C CA  . PRO A 1 134 ? -76.439 7.864   132.249 1.00 12.37  ? 134 PRO A CA  1 
ATOM 1076 C C   . PRO A 1 134 ? -76.083 6.736   133.200 1.00 12.37  ? 134 PRO A C   1 
ATOM 1077 O O   . PRO A 1 134 ? -74.988 6.726   133.791 1.00 12.37  ? 134 PRO A O   1 
ATOM 1078 C CB  . PRO A 1 134 ? -75.903 7.596   130.831 1.00 12.37  ? 134 PRO A CB  1 
ATOM 1079 C CG  . PRO A 1 134 ? -74.589 8.268   130.800 1.00 12.37  ? 134 PRO A CG  1 
ATOM 1080 C CD  . PRO A 1 134 ? -74.736 9.492   131.661 1.00 12.37  ? 134 PRO A CD  1 
ATOM 1081 N N   . PRO A 1 135 ? -76.977 5.761   133.387 1.00 13.21  ? 135 PRO A N   1 
ATOM 1082 C CA  . PRO A 1 135 ? -76.715 4.708   134.382 1.00 13.21  ? 135 PRO A CA  1 
ATOM 1083 C C   . PRO A 1 135 ? -75.515 3.830   134.065 1.00 13.21  ? 135 PRO A C   1 
ATOM 1084 O O   . PRO A 1 135 ? -74.875 3.321   134.992 1.00 13.21  ? 135 PRO A O   1 
ATOM 1085 C CB  . PRO A 1 135 ? -78.018 3.892   134.380 1.00 13.21  ? 135 PRO A CB  1 
ATOM 1086 C CG  . PRO A 1 135 ? -79.050 4.830   133.883 1.00 13.21  ? 135 PRO A CG  1 
ATOM 1087 C CD  . PRO A 1 135 ? -78.344 5.655   132.850 1.00 13.21  ? 135 PRO A CD  1 
ATOM 1088 N N   . ASN A 1 136 ? -75.192 3.630   132.789 1.00 13.17  ? 136 ASN A N   1 
ATOM 1089 C CA  . ASN A 1 136 ? -74.011 2.861   132.397 1.00 13.17  ? 136 ASN A CA  1 
ATOM 1090 C C   . ASN A 1 136 ? -72.783 3.763   132.409 1.00 13.17  ? 136 ASN A C   1 
ATOM 1091 O O   . ASN A 1 136 ? -72.582 4.576   131.505 1.00 13.17  ? 136 ASN A O   1 
ATOM 1092 C CB  . ASN A 1 136 ? -74.219 2.239   131.023 1.00 13.17  ? 136 ASN A CB  1 
ATOM 1093 C CG  . ASN A 1 136 ? -75.355 1.238   131.004 1.00 13.17  ? 136 ASN A CG  1 
ATOM 1094 O OD1 . ASN A 1 136 ? -75.210 0.111   131.478 1.00 13.17  ? 136 ASN A OD1 1 
ATOM 1095 N ND2 . ASN A 1 136 ? -76.494 1.640   130.454 1.00 13.17  ? 136 ASN A ND2 1 
ATOM 1096 N N   . ALA A 1 137 ? -71.958 3.615   133.442 1.00 10.79  ? 137 ALA A N   1 
ATOM 1097 C CA  . ALA A 1 137 ? -70.622 4.182   133.422 1.00 10.79  ? 137 ALA A CA  1 
ATOM 1098 C C   . ALA A 1 137 ? -69.804 3.574   132.282 1.00 10.79  ? 137 ALA A C   1 
ATOM 1099 O O   . ALA A 1 137 ? -70.033 2.428   131.885 1.00 10.79  ? 137 ALA A O   1 
ATOM 1100 C CB  . ALA A 1 137 ? -69.919 3.938   134.755 1.00 10.79  ? 137 ALA A CB  1 
ATOM 1101 N N   . PRO A 1 138 ? -68.843 4.321   131.736 1.00 10.16  ? 138 PRO A N   1 
ATOM 1102 C CA  . PRO A 1 138 ? -67.933 3.736   130.745 1.00 10.16  ? 138 PRO A CA  1 
ATOM 1103 C C   . PRO A 1 138 ? -67.212 2.514   131.291 1.00 10.16  ? 138 PRO A C   1 
ATOM 1104 O O   . PRO A 1 138 ? -66.855 2.455   132.469 1.00 10.16  ? 138 PRO A O   1 
ATOM 1105 C CB  . PRO A 1 138 ? -66.954 4.880   130.444 1.00 10.16  ? 138 PRO A CB  1 
ATOM 1106 C CG  . PRO A 1 138 ? -67.693 6.112   130.801 1.00 10.16  ? 138 PRO A CG  1 
ATOM 1107 C CD  . PRO A 1 138 ? -68.517 5.731   131.995 1.00 10.16  ? 138 PRO A CD  1 
ATOM 1108 N N   . ILE A 1 139 ? -66.997 1.533   130.417 1.00 11.29  ? 139 ILE A N   1 
ATOM 1109 C CA  . ILE A 1 139 ? -66.240 0.336   130.759 1.00 11.29  ? 139 ILE A CA  1 
ATOM 1110 C C   . ILE A 1 139 ? -65.338 -0.019  129.585 1.00 11.29  ? 139 ILE A C   1 
ATOM 1111 O O   . ILE A 1 139 ? -65.689 0.186   128.420 1.00 11.29  ? 139 ILE A O   1 
ATOM 1112 C CB  . ILE A 1 139 ? -67.168 -0.847  131.122 1.00 11.29  ? 139 ILE A CB  1 
ATOM 1113 C CG1 . ILE A 1 139 ? -66.378 -1.946  131.832 1.00 11.29  ? 139 ILE A CG1 1 
ATOM 1114 C CG2 . ILE A 1 139 ? -67.858 -1.398  129.879 1.00 11.29  ? 139 ILE A CG2 1 
ATOM 1115 C CD1 . ILE A 1 139 ? -67.247 -2.960  132.541 1.00 11.29  ? 139 ILE A CD1 1 
ATOM 1116 N N   . LEU A 1 140 ? -64.163 -0.554  129.906 1.00 12.48  ? 140 LEU A N   1 
ATOM 1117 C CA  . LEU A 1 140 ? -63.261 -1.099  128.901 1.00 12.48  ? 140 LEU A CA  1 
ATOM 1118 C C   . LEU A 1 140 ? -63.707 -2.490  128.470 1.00 12.48  ? 140 LEU A C   1 
ATOM 1119 O O   . LEU A 1 140 ? -64.092 -3.319  129.300 1.00 12.48  ? 140 LEU A O   1 
ATOM 1120 C CB  . LEU A 1 140 ? -61.837 -1.143  129.453 1.00 12.48  ? 140 LEU A CB  1 
ATOM 1121 C CG  . LEU A 1 140 ? -61.164 0.223   129.595 1.00 12.48  ? 140 LEU A CG  1 
ATOM 1122 C CD1 . LEU A 1 140 ? -60.010 0.169   130.580 1.00 12.48  ? 140 LEU A CD1 1 
ATOM 1123 C CD2 . LEU A 1 140 ? -60.682 0.714   128.240 1.00 12.48  ? 140 LEU A CD2 1 
ATOM 1124 N N   . SER A 1 141 ? -63.659 -2.745  127.162 1.00 25.98  ? 141 SER A N   1 
ATOM 1125 C CA  . SER A 1 141 ? -63.920 -4.079  126.644 1.00 25.98  ? 141 SER A CA  1 
ATOM 1126 C C   . SER A 1 141 ? -63.170 -4.268  125.333 1.00 25.98  ? 141 SER A C   1 
ATOM 1127 O O   . SER A 1 141 ? -62.830 -3.306  124.641 1.00 25.98  ? 141 SER A O   1 
ATOM 1128 C CB  . SER A 1 141 ? -65.420 -4.320  126.436 1.00 25.98  ? 141 SER A CB  1 
ATOM 1129 O OG  . SER A 1 141 ? -65.881 -3.684  125.257 1.00 25.98  ? 141 SER A OG  1 
ATOM 1130 N N   . THR A 1 142 ? -62.914 -5.535  125.005 1.00 30.60  ? 142 THR A N   1 
ATOM 1131 C CA  . THR A 1 142 ? -62.238 -5.924  123.775 1.00 30.60  ? 142 THR A CA  1 
ATOM 1132 C C   . THR A 1 142 ? -63.197 -6.470  122.724 1.00 30.60  ? 142 THR A C   1 
ATOM 1133 O O   . THR A 1 142 ? -62.745 -6.945  121.678 1.00 30.60  ? 142 THR A O   1 
ATOM 1134 C CB  . THR A 1 142 ? -61.158 -6.967  124.074 1.00 30.60  ? 142 THR A CB  1 
ATOM 1135 O OG1 . THR A 1 142 ? -61.749 -8.108  124.706 1.00 30.60  ? 142 THR A OG1 1 
ATOM 1136 C CG2 . THR A 1 142 ? -60.086 -6.382  124.981 1.00 30.60  ? 142 THR A CG2 1 
ATOM 1137 N N   . LEU A 1 143 ? -64.500 -6.423  122.980 1.00 43.33  ? 143 LEU A N   1 
ATOM 1138 C CA  . LEU A 1 143 ? -65.462 -6.986  122.046 1.00 43.33  ? 143 LEU A CA  1 
ATOM 1139 C C   . LEU A 1 143 ? -65.333 -6.321  120.675 1.00 43.33  ? 143 LEU A C   1 
ATOM 1140 O O   . LEU A 1 143 ? -65.100 -5.109  120.589 1.00 43.33  ? 143 LEU A O   1 
ATOM 1141 C CB  . LEU A 1 143 ? -66.887 -6.818  122.578 1.00 43.33  ? 143 LEU A CB  1 
ATOM 1142 C CG  . LEU A 1 143 ? -67.382 -7.877  123.570 1.00 43.33  ? 143 LEU A CG  1 
ATOM 1143 C CD1 . LEU A 1 143 ? -67.456 -9.253  122.920 1.00 43.33  ? 143 LEU A CD1 1 
ATOM 1144 C CD2 . LEU A 1 143 ? -66.498 -7.920  124.803 1.00 43.33  ? 143 LEU A CD2 1 
ATOM 1145 N N   . PRO A 1 144 ? -65.479 -7.083  119.586 1.00 52.18  ? 144 PRO A N   1 
ATOM 1146 C CA  . PRO A 1 144 ? -65.024 -6.596  118.272 1.00 52.18  ? 144 PRO A CA  1 
ATOM 1147 C C   . PRO A 1 144 ? -65.788 -5.386  117.761 1.00 52.18  ? 144 PRO A C   1 
ATOM 1148 O O   . PRO A 1 144 ? -65.274 -4.681  116.884 1.00 52.18  ? 144 PRO A O   1 
ATOM 1149 C CB  . PRO A 1 144 ? -65.236 -7.810  117.353 1.00 52.18  ? 144 PRO A CB  1 
ATOM 1150 C CG  . PRO A 1 144 ? -66.300 -8.609  118.028 1.00 52.18  ? 144 PRO A CG  1 
ATOM 1151 C CD  . PRO A 1 144 ? -66.036 -8.442  119.497 1.00 52.18  ? 144 PRO A CD  1 
ATOM 1152 N N   . MET B 1 1   ? -46.746 -14.166 142.340 1.00 17.50  ? 1   MET B N   1 
ATOM 1153 C CA  . MET B 1 1   ? -45.822 -14.661 141.286 1.00 17.50  ? 1   MET B CA  1 
ATOM 1154 C C   . MET B 1 1   ? -44.396 -14.695 141.812 1.00 17.50  ? 1   MET B C   1 
ATOM 1155 O O   . MET B 1 1   ? -44.115 -14.189 142.899 1.00 17.50  ? 1   MET B O   1 
ATOM 1156 C CB  . MET B 1 1   ? -45.895 -13.763 140.048 1.00 17.50  ? 1   MET B CB  1 
ATOM 1157 C CG  . MET B 1 1   ? -47.201 -13.860 139.266 1.00 17.50  ? 1   MET B CG  1 
ATOM 1158 S SD  . MET B 1 1   ? -47.438 -12.471 138.143 1.00 17.50  ? 1   MET B SD  1 
ATOM 1159 C CE  . MET B 1 1   ? -48.200 -11.289 139.247 1.00 17.50  ? 1   MET B CE  1 
ATOM 1160 N N   . ASP B 1 2   ? -43.498 -15.293 141.036 1.00 18.98  ? 2   ASP B N   1 
ATOM 1161 C CA  . ASP B 1 2   ? -42.078 -15.330 141.361 1.00 18.98  ? 2   ASP B CA  1 
ATOM 1162 C C   . ASP B 1 2   ? -41.359 -14.503 140.308 1.00 18.98  ? 2   ASP B C   1 
ATOM 1163 O O   . ASP B 1 2   ? -41.275 -14.905 139.143 1.00 18.98  ? 2   ASP B O   1 
ATOM 1164 C CB  . ASP B 1 2   ? -41.555 -16.765 141.389 1.00 18.98  ? 2   ASP B CB  1 
ATOM 1165 C CG  . ASP B 1 2   ? -40.225 -16.890 142.106 1.00 18.98  ? 2   ASP B CG  1 
ATOM 1166 O OD1 . ASP B 1 2   ? -39.876 -15.975 142.878 1.00 18.98  ? 2   ASP B OD1 1 
ATOM 1167 O OD2 . ASP B 1 2   ? -39.535 -17.913 141.905 1.00 18.98  ? 2   ASP B OD2 1 
ATOM 1168 N N   . ILE B 1 3   ? -40.830 -13.358 140.724 1.00 14.74  ? 3   ILE B N   1 
ATOM 1169 C CA  . ILE B 1 3   ? -40.183 -12.415 139.824 1.00 14.74  ? 3   ILE B CA  1 
ATOM 1170 C C   . ILE B 1 3   ? -38.781 -12.142 140.342 1.00 14.74  ? 3   ILE B C   1 
ATOM 1171 O O   . ILE B 1 3   ? -38.594 -11.885 141.537 1.00 14.74  ? 3   ILE B O   1 
ATOM 1172 C CB  . ILE B 1 3   ? -40.992 -11.109 139.696 1.00 14.74  ? 3   ILE B CB  1 
ATOM 1173 C CG1 . ILE B 1 3   ? -42.409 -11.418 139.211 1.00 14.74  ? 3   ILE B CG1 1 
ATOM 1174 C CG2 . ILE B 1 3   ? -40.327 -10.139 138.715 1.00 14.74  ? 3   ILE B CG2 1 
ATOM 1175 C CD1 . ILE B 1 3   ? -43.244 -10.187 138.936 1.00 14.74  ? 3   ILE B CD1 1 
ATOM 1176 N N   . ASP B 1 4   ? -37.809 -12.202 139.455 1.00 13.26  ? 4   ASP B N   1 
ATOM 1177 C CA  . ASP B 1 4   ? -36.450 -11.851 139.833 1.00 13.26  ? 4   ASP B CA  1 
ATOM 1178 C C   . ASP B 1 4   ? -36.139 -10.476 139.269 1.00 13.26  ? 4   ASP B C   1 
ATOM 1179 O O   . ASP B 1 4   ? -36.290 -10.270 138.057 1.00 13.26  ? 4   ASP B O   1 
ATOM 1180 C CB  . ASP B 1 4   ? -35.459 -12.880 139.295 1.00 13.26  ? 4   ASP B CB  1 
ATOM 1181 C CG  . ASP B 1 4   ? -34.042 -12.648 139.786 1.00 13.26  ? 4   ASP B CG  1 
ATOM 1182 O OD1 . ASP B 1 4   ? -33.529 -11.520 139.638 1.00 13.26  ? 4   ASP B OD1 1 
ATOM 1183 O OD2 . ASP B 1 4   ? -33.438 -13.602 140.316 1.00 13.26  ? 4   ASP B OD2 1 
ATOM 1184 N N   . PRO B 1 5   ? -35.714 -9.507  140.085 1.00 12.33  ? 5   PRO B N   1 
ATOM 1185 C CA  . PRO B 1 5   ? -35.516 -8.155  139.536 1.00 12.33  ? 5   PRO B CA  1 
ATOM 1186 C C   . PRO B 1 5   ? -34.479 -8.092  138.432 1.00 12.33  ? 5   PRO B C   1 
ATOM 1187 O O   . PRO B 1 5   ? -34.653 -7.328  137.474 1.00 12.33  ? 5   PRO B O   1 
ATOM 1188 C CB  . PRO B 1 5   ? -35.089 -7.334  140.766 1.00 12.33  ? 5   PRO B CB  1 
ATOM 1189 C CG  . PRO B 1 5   ? -34.675 -8.328  141.789 1.00 12.33  ? 5   PRO B CG  1 
ATOM 1190 C CD  . PRO B 1 5   ? -35.477 -9.556  141.536 1.00 12.33  ? 5   PRO B CD  1 
ATOM 1191 N N   . TYR B 1 6   ? -33.401 -8.867  138.531 1.00 11.15  ? 6   TYR B N   1 
ATOM 1192 C CA  . TYR B 1 6   ? -32.312 -8.771  137.571 1.00 11.15  ? 6   TYR B CA  1 
ATOM 1193 C C   . TYR B 1 6   ? -32.427 -9.753  136.412 1.00 11.15  ? 6   TYR B C   1 
ATOM 1194 O O   . TYR B 1 6   ? -31.592 -9.706  135.503 1.00 11.15  ? 6   TYR B O   1 
ATOM 1195 C CB  . TYR B 1 6   ? -30.981 -8.978  138.298 1.00 11.15  ? 6   TYR B CB  1 
ATOM 1196 C CG  . TYR B 1 6   ? -30.926 -8.273  139.633 1.00 11.15  ? 6   TYR B CG  1 
ATOM 1197 C CD1 . TYR B 1 6   ? -30.797 -6.893  139.708 1.00 11.15  ? 6   TYR B CD1 1 
ATOM 1198 C CD2 . TYR B 1 6   ? -31.017 -8.986  140.819 1.00 11.15  ? 6   TYR B CD2 1 
ATOM 1199 C CE1 . TYR B 1 6   ? -30.750 -6.244  140.926 1.00 11.15  ? 6   TYR B CE1 1 
ATOM 1200 C CE2 . TYR B 1 6   ? -30.972 -8.347  142.042 1.00 11.15  ? 6   TYR B CE2 1 
ATOM 1201 C CZ  . TYR B 1 6   ? -30.841 -6.975  142.089 1.00 11.15  ? 6   TYR B CZ  1 
ATOM 1202 O OH  . TYR B 1 6   ? -30.797 -6.334  143.305 1.00 11.15  ? 6   TYR B OH  1 
ATOM 1203 N N   . LYS B 1 7   ? -33.430 -10.636 136.409 1.00 13.45  ? 7   LYS B N   1 
ATOM 1204 C CA  . LYS B 1 7   ? -33.493 -11.658 135.367 1.00 13.45  ? 7   LYS B CA  1 
ATOM 1205 C C   . LYS B 1 7   ? -33.643 -11.026 133.994 1.00 13.45  ? 7   LYS B C   1 
ATOM 1206 O O   . LYS B 1 7   ? -33.040 -11.481 133.017 1.00 13.45  ? 7   LYS B O   1 
ATOM 1207 C CB  . LYS B 1 7   ? -34.645 -12.631 135.612 1.00 13.45  ? 7   LYS B CB  1 
ATOM 1208 C CG  . LYS B 1 7   ? -34.634 -13.792 134.627 1.00 13.45  ? 7   LYS B CG  1 
ATOM 1209 C CD  . LYS B 1 7   ? -35.754 -14.788 134.858 1.00 13.45  ? 7   LYS B CD  1 
ATOM 1210 C CE  . LYS B 1 7   ? -35.677 -15.909 133.831 1.00 13.45  ? 7   LYS B CE  1 
ATOM 1211 N NZ  . LYS B 1 7   ? -36.758 -16.917 133.986 1.00 13.45  ? 7   LYS B NZ  1 
ATOM 1212 N N   . GLU B 1 8   ? -34.449 -9.968  133.907 1.00 13.36  ? 8   GLU B N   1 
ATOM 1213 C CA  . GLU B 1 8   ? -34.669 -9.304  132.635 1.00 13.36  ? 8   GLU B CA  1 
ATOM 1214 C C   . GLU B 1 8   ? -33.385 -8.675  132.103 1.00 13.36  ? 8   GLU B C   1 
ATOM 1215 O O   . GLU B 1 8   ? -33.189 -8.600  130.885 1.00 13.36  ? 8   GLU B O   1 
ATOM 1216 C CB  . GLU B 1 8   ? -35.767 -8.259  132.830 1.00 13.36  ? 8   GLU B CB  1 
ATOM 1217 C CG  . GLU B 1 8   ? -36.178 -7.520  131.605 1.00 13.36  ? 8   GLU B CG  1 
ATOM 1218 C CD  . GLU B 1 8   ? -37.301 -6.541  131.875 1.00 13.36  ? 8   GLU B CD  1 
ATOM 1219 O OE1 . GLU B 1 8   ? -37.724 -6.426  133.043 1.00 13.36  ? 8   GLU B OE1 1 
ATOM 1220 O OE2 . GLU B 1 8   ? -37.756 -5.879  130.920 1.00 13.36  ? 8   GLU B OE2 1 
ATOM 1221 N N   . PHE B 1 9   ? -32.510 -8.215  132.994 1.00 11.86  ? 9   PHE B N   1 
ATOM 1222 C CA  . PHE B 1 9   ? -31.280 -7.529  132.624 1.00 11.86  ? 9   PHE B CA  1 
ATOM 1223 C C   . PHE B 1 9   ? -30.099 -8.483  132.460 1.00 11.86  ? 9   PHE B C   1 
ATOM 1224 O O   . PHE B 1 9   ? -28.959 -8.023  132.349 1.00 11.86  ? 9   PHE B O   1 
ATOM 1225 C CB  . PHE B 1 9   ? -30.961 -6.439  133.648 1.00 11.86  ? 9   PHE B CB  1 
ATOM 1226 C CG  . PHE B 1 9   ? -32.091 -5.474  133.862 1.00 11.86  ? 9   PHE B CG  1 
ATOM 1227 C CD1 . PHE B 1 9   ? -32.320 -4.457  132.951 1.00 11.86  ? 9   PHE B CD1 1 
ATOM 1228 C CD2 . PHE B 1 9   ? -32.935 -5.595  134.950 1.00 11.86  ? 9   PHE B CD2 1 
ATOM 1229 C CE1 . PHE B 1 9   ? -33.360 -3.570  133.128 1.00 11.86  ? 9   PHE B CE1 1 
ATOM 1230 C CE2 . PHE B 1 9   ? -33.978 -4.707  135.132 1.00 11.86  ? 9   PHE B CE2 1 
ATOM 1231 C CZ  . PHE B 1 9   ? -34.190 -3.694  134.219 1.00 11.86  ? 9   PHE B CZ  1 
ATOM 1232 N N   . GLY B 1 10  ? -30.342 -9.791  132.460 1.00 11.62  ? 10  GLY B N   1 
ATOM 1233 C CA  . GLY B 1 10  ? -29.304 -10.768 132.212 1.00 11.62  ? 10  GLY B CA  1 
ATOM 1234 C C   . GLY B 1 10  ? -28.526 -11.197 133.435 1.00 11.62  ? 10  GLY B C   1 
ATOM 1235 O O   . GLY B 1 10  ? -27.488 -11.854 133.290 1.00 11.62  ? 10  GLY B O   1 
ATOM 1236 N N   . ALA B 1 11  ? -28.989 -10.843 134.629 1.00 11.20  ? 11  ALA B N   1 
ATOM 1237 C CA  . ALA B 1 11  ? -28.341 -11.175 135.888 1.00 11.20  ? 11  ALA B CA  1 
ATOM 1238 C C   . ALA B 1 11  ? -29.347 -11.885 136.781 1.00 11.20  ? 11  ALA B C   1 
ATOM 1239 O O   . ALA B 1 11  ? -30.545 -11.918 136.495 1.00 11.20  ? 11  ALA B O   1 
ATOM 1240 C CB  . ALA B 1 11  ? -27.781 -9.926  136.580 1.00 11.20  ? 11  ALA B CB  1 
ATOM 1241 N N   . THR B 1 12  ? -28.854 -12.476 137.865 1.00 11.46  ? 12  THR B N   1 
ATOM 1242 C CA  . THR B 1 12  ? -29.705 -13.182 138.811 1.00 11.46  ? 12  THR B CA  1 
ATOM 1243 C C   . THR B 1 12  ? -29.448 -12.657 140.216 1.00 11.46  ? 12  THR B C   1 
ATOM 1244 O O   . THR B 1 12  ? -28.409 -12.057 140.499 1.00 11.46  ? 12  THR B O   1 
ATOM 1245 C CB  . THR B 1 12  ? -29.467 -14.701 138.766 1.00 11.46  ? 12  THR B CB  1 
ATOM 1246 O OG1 . THR B 1 12  ? -28.091 -14.981 139.051 1.00 11.46  ? 12  THR B OG1 1 
ATOM 1247 C CG2 . THR B 1 12  ? -29.826 -15.262 137.399 1.00 11.46  ? 12  THR B CG2 1 
ATOM 1248 N N   . VAL B 1 13  ? -30.426 -12.884 141.095 1.00 11.93  ? 13  VAL B N   1 
ATOM 1249 C CA  . VAL B 1 13  ? -30.248 -12.583 142.512 1.00 11.93  ? 13  VAL B CA  1 
ATOM 1250 C C   . VAL B 1 13  ? -29.049 -13.328 143.081 1.00 11.93  ? 13  VAL B C   1 
ATOM 1251 O O   . VAL B 1 13  ? -28.307 -12.793 143.911 1.00 11.93  ? 13  VAL B O   1 
ATOM 1252 C CB  . VAL B 1 13  ? -31.539 -12.909 143.288 1.00 11.93  ? 13  VAL B CB  1 
ATOM 1253 C CG1 . VAL B 1 13  ? -31.278 -12.977 144.790 1.00 11.93  ? 13  VAL B CG1 1 
ATOM 1254 C CG2 . VAL B 1 13  ? -32.611 -11.880 142.982 1.00 11.93  ? 13  VAL B CG2 1 
ATOM 1255 N N   . GLU B 1 14  ? -28.846 -14.577 142.660 1.00 12.39  ? 14  GLU B N   1 
ATOM 1256 C CA  . GLU B 1 14  ? -27.677 -15.331 143.103 1.00 12.39  ? 14  GLU B CA  1 
ATOM 1257 C C   . GLU B 1 14  ? -26.376 -14.626 142.734 1.00 12.39  ? 14  GLU B C   1 
ATOM 1258 O O   . GLU B 1 14  ? -25.457 -14.522 143.554 1.00 12.39  ? 14  GLU B O   1 
ATOM 1259 C CB  . GLU B 1 14  ? -27.706 -16.740 142.507 1.00 12.39  ? 14  GLU B CB  1 
ATOM 1260 C CG  . GLU B 1 14  ? -28.771 -17.659 143.095 1.00 12.39  ? 14  GLU B CG  1 
ATOM 1261 C CD  . GLU B 1 14  ? -30.172 -17.328 142.616 1.00 12.39  ? 14  GLU B CD  1 
ATOM 1262 O OE1 . GLU B 1 14  ? -30.365 -17.187 141.390 1.00 12.39  ? 14  GLU B OE1 1 
ATOM 1263 O OE2 . GLU B 1 14  ? -31.081 -17.209 143.465 1.00 12.39  ? 14  GLU B OE2 1 
ATOM 1264 N N   . LEU B 1 15  ? -26.281 -14.135 141.498 1.00 10.65  ? 15  LEU B N   1 
ATOM 1265 C CA  . LEU B 1 15  ? -25.060 -13.476 141.046 1.00 10.65  ? 15  LEU B CA  1 
ATOM 1266 C C   . LEU B 1 15  ? -24.738 -12.229 141.867 1.00 10.65  ? 15  LEU B C   1 
ATOM 1267 O O   . LEU B 1 15  ? -23.579 -12.002 142.233 1.00 10.65  ? 15  LEU B O   1 
ATOM 1268 C CB  . LEU B 1 15  ? -25.184 -13.126 139.564 1.00 10.65  ? 15  LEU B CB  1 
ATOM 1269 C CG  . LEU B 1 15  ? -23.996 -12.410 138.921 1.00 10.65  ? 15  LEU B CG  1 
ATOM 1270 C CD1 . LEU B 1 15  ? -22.771 -13.310 138.918 1.00 10.65  ? 15  LEU B CD1 1 
ATOM 1271 C CD2 . LEU B 1 15  ? -24.348 -11.976 137.508 1.00 10.65  ? 15  LEU B CD2 1 
ATOM 1272 N N   . LEU B 1 16  ? -25.746 -11.406 142.163 1.00 10.65  ? 16  LEU B N   1 
ATOM 1273 C CA  . LEU B 1 16  ? -25.531 -10.209 142.973 1.00 10.65  ? 16  LEU B CA  1 
ATOM 1274 C C   . LEU B 1 16  ? -25.410 -10.487 144.468 1.00 10.65  ? 16  LEU B C   1 
ATOM 1275 O O   . LEU B 1 16  ? -24.877 -9.642  145.194 1.00 10.65  ? 16  LEU B O   1 
ATOM 1276 C CB  . LEU B 1 16  ? -26.669 -9.214  142.735 1.00 10.65  ? 16  LEU B CB  1 
ATOM 1277 C CG  . LEU B 1 16  ? -26.483 -8.299  141.521 1.00 10.65  ? 16  LEU B CG  1 
ATOM 1278 C CD1 . LEU B 1 16  ? -26.515 -9.105  140.231 1.00 10.65  ? 16  LEU B CD1 1 
ATOM 1279 C CD2 . LEU B 1 16  ? -27.538 -7.209  141.502 1.00 10.65  ? 16  LEU B CD2 1 
ATOM 1280 N N   . SER B 1 17  ? -25.890 -11.635 144.944 1.00 11.48  ? 17  SER B N   1 
ATOM 1281 C CA  . SER B 1 17  ? -25.877 -11.917 146.377 1.00 11.48  ? 17  SER B CA  1 
ATOM 1282 C C   . SER B 1 17  ? -24.469 -12.043 146.945 1.00 11.48  ? 17  SER B C   1 
ATOM 1283 O O   . SER B 1 17  ? -24.301 -11.964 148.166 1.00 11.48  ? 17  SER B O   1 
ATOM 1284 C CB  . SER B 1 17  ? -26.658 -13.202 146.658 1.00 11.48  ? 17  SER B CB  1 
ATOM 1285 O OG  . SER B 1 17  ? -25.955 -14.338 146.185 1.00 11.48  ? 17  SER B OG  1 
ATOM 1286 N N   . PHE B 1 18  ? -23.460 -12.241 146.097 1.00 10.51  ? 18  PHE B N   1 
ATOM 1287 C CA  . PHE B 1 18  ? -22.085 -12.342 146.574 1.00 10.51  ? 18  PHE B CA  1 
ATOM 1288 C C   . PHE B 1 18  ? -21.508 -11.007 147.032 1.00 10.51  ? 18  PHE B C   1 
ATOM 1289 O O   . PHE B 1 18  ? -20.582 -11.003 147.850 1.00 10.51  ? 18  PHE B O   1 
ATOM 1290 C CB  . PHE B 1 18  ? -21.208 -12.940 145.475 1.00 10.51  ? 18  PHE B CB  1 
ATOM 1291 C CG  . PHE B 1 18  ? -21.404 -14.417 145.286 1.00 10.51  ? 18  PHE B CG  1 
ATOM 1292 C CD1 . PHE B 1 18  ? -20.906 -15.321 146.208 1.00 10.51  ? 18  PHE B CD1 1 
ATOM 1293 C CD2 . PHE B 1 18  ? -22.089 -14.901 144.184 1.00 10.51  ? 18  PHE B CD2 1 
ATOM 1294 C CE1 . PHE B 1 18  ? -21.089 -16.681 146.036 1.00 10.51  ? 18  PHE B CE1 1 
ATOM 1295 C CE2 . PHE B 1 18  ? -22.276 -16.258 144.008 1.00 10.51  ? 18  PHE B CE2 1 
ATOM 1296 C CZ  . PHE B 1 18  ? -21.779 -17.148 144.936 1.00 10.51  ? 18  PHE B CZ  1 
ATOM 1297 N N   . LEU B 1 19  ? -22.018 -9.886  146.538 1.00 9.99   ? 19  LEU B N   1 
ATOM 1298 C CA  . LEU B 1 19  ? -21.562 -8.589  147.022 1.00 9.99   ? 19  LEU B CA  1 
ATOM 1299 C C   . LEU B 1 19  ? -21.875 -8.424  148.509 1.00 9.99   ? 19  LEU B C   1 
ATOM 1300 O O   . LEU B 1 19  ? -23.028 -8.612  148.920 1.00 9.99   ? 19  LEU B O   1 
ATOM 1301 C CB  . LEU B 1 19  ? -22.217 -7.459  146.231 1.00 9.99   ? 19  LEU B CB  1 
ATOM 1302 C CG  . LEU B 1 19  ? -21.932 -7.405  144.729 1.00 9.99   ? 19  LEU B CG  1 
ATOM 1303 C CD1 . LEU B 1 19  ? -22.763 -6.314  144.079 1.00 9.99   ? 19  LEU B CD1 1 
ATOM 1304 C CD2 . LEU B 1 19  ? -20.454 -7.171  144.468 1.00 9.99   ? 19  LEU B CD2 1 
ATOM 1305 N N   . PRO B 1 20  ? -20.890 -8.079  149.341 1.00 10.71  ? 20  PRO B N   1 
ATOM 1306 C CA  . PRO B 1 20  ? -21.164 -7.864  150.765 1.00 10.71  ? 20  PRO B CA  1 
ATOM 1307 C C   . PRO B 1 20  ? -21.900 -6.554  151.019 1.00 10.71  ? 20  PRO B C   1 
ATOM 1308 O O   . PRO B 1 20  ? -21.842 -5.609  150.229 1.00 10.71  ? 20  PRO B O   1 
ATOM 1309 C CB  . PRO B 1 20  ? -19.764 -7.856  151.388 1.00 10.71  ? 20  PRO B CB  1 
ATOM 1310 C CG  . PRO B 1 20  ? -18.901 -7.305  150.303 1.00 10.71  ? 20  PRO B CG  1 
ATOM 1311 C CD  . PRO B 1 20  ? -19.471 -7.845  149.020 1.00 10.71  ? 20  PRO B CD  1 
ATOM 1312 N N   . SER B 1 21  ? -22.609 -6.515  152.152 1.00 13.07  ? 21  SER B N   1 
ATOM 1313 C CA  . SER B 1 21  ? -23.399 -5.335  152.498 1.00 13.07  ? 21  SER B CA  1 
ATOM 1314 C C   . SER B 1 21  ? -22.547 -4.076  152.631 1.00 13.07  ? 21  SER B C   1 
ATOM 1315 O O   . SER B 1 21  ? -23.044 -2.968  152.396 1.00 13.07  ? 21  SER B O   1 
ATOM 1316 C CB  . SER B 1 21  ? -24.158 -5.584  153.803 1.00 13.07  ? 21  SER B CB  1 
ATOM 1317 O OG  . SER B 1 21  ? -25.006 -6.714  153.697 1.00 13.07  ? 21  SER B OG  1 
ATOM 1318 N N   . ASP B 1 22  ? -21.271 -4.215  152.997 1.00 12.64  ? 22  ASP B N   1 
ATOM 1319 C CA  . ASP B 1 22  ? -20.381 -3.059  153.069 1.00 12.64  ? 22  ASP B CA  1 
ATOM 1320 C C   . ASP B 1 22  ? -20.092 -2.469  151.694 1.00 12.64  ? 22  ASP B C   1 
ATOM 1321 O O   . ASP B 1 22  ? -19.627 -1.327  151.608 1.00 12.64  ? 22  ASP B O   1 
ATOM 1322 C CB  . ASP B 1 22  ? -19.078 -3.429  153.786 1.00 12.64  ? 22  ASP B CB  1 
ATOM 1323 C CG  . ASP B 1 22  ? -18.287 -4.486  153.054 1.00 12.64  ? 22  ASP B CG  1 
ATOM 1324 O OD1 . ASP B 1 22  ? -18.789 -5.006  152.044 1.00 12.64  ? 22  ASP B OD1 1 
ATOM 1325 O OD2 . ASP B 1 22  ? -17.157 -4.794  153.488 1.00 12.64  ? 22  ASP B OD2 1 
ATOM 1326 N N   . PHE B 1 23  ? -20.350 -3.224  150.626 1.00 10.37  ? 23  PHE B N   1 
ATOM 1327 C CA  . PHE B 1 23  ? -19.951 -2.801  149.288 1.00 10.37  ? 23  PHE B CA  1 
ATOM 1328 C C   . PHE B 1 23  ? -20.808 -1.649  148.773 1.00 10.37  ? 23  PHE B C   1 
ATOM 1329 O O   . PHE B 1 23  ? -20.287 -0.707  148.167 1.00 10.37  ? 23  PHE B O   1 
ATOM 1330 C CB  . PHE B 1 23  ? -20.030 -3.998  148.338 1.00 10.37  ? 23  PHE B CB  1 
ATOM 1331 C CG  . PHE B 1 23  ? -19.725 -3.666  146.907 1.00 10.37  ? 23  PHE B CG  1 
ATOM 1332 C CD1 . PHE B 1 23  ? -18.420 -3.646  146.447 1.00 10.37  ? 23  PHE B CD1 1 
ATOM 1333 C CD2 . PHE B 1 23  ? -20.748 -3.380  146.019 1.00 10.37  ? 23  PHE B CD2 1 
ATOM 1334 C CE1 . PHE B 1 23  ? -18.143 -3.344  145.128 1.00 10.37  ? 23  PHE B CE1 1 
ATOM 1335 C CE2 . PHE B 1 23  ? -20.477 -3.076  144.703 1.00 10.37  ? 23  PHE B CE2 1 
ATOM 1336 C CZ  . PHE B 1 23  ? -19.173 -3.063  144.254 1.00 10.37  ? 23  PHE B CZ  1 
ATOM 1337 N N   . PHE B 1 24  ? -22.120 -1.698  149.003 1.00 10.89  ? 24  PHE B N   1 
ATOM 1338 C CA  . PHE B 1 24  ? -23.002 -0.675  148.450 1.00 10.89  ? 24  PHE B CA  1 
ATOM 1339 C C   . PHE B 1 24  ? -22.879 0.632   149.239 1.00 10.89  ? 24  PHE B C   1 
ATOM 1340 O O   . PHE B 1 24  ? -22.786 0.607   150.469 1.00 10.89  ? 24  PHE B O   1 
ATOM 1341 C CB  . PHE B 1 24  ? -24.446 -1.163  148.471 1.00 10.89  ? 24  PHE B CB  1 
ATOM 1342 C CG  . PHE B 1 24  ? -24.624 -2.529  147.879 1.00 10.89  ? 24  PHE B CG  1 
ATOM 1343 C CD1 . PHE B 1 24  ? -24.591 -2.714  146.508 1.00 10.89  ? 24  PHE B CD1 1 
ATOM 1344 C CD2 . PHE B 1 24  ? -24.809 -3.631  148.694 1.00 10.89  ? 24  PHE B CD2 1 
ATOM 1345 C CE1 . PHE B 1 24  ? -24.751 -3.970  145.962 1.00 10.89  ? 24  PHE B CE1 1 
ATOM 1346 C CE2 . PHE B 1 24  ? -24.969 -4.890  148.153 1.00 10.89  ? 24  PHE B CE2 1 
ATOM 1347 C CZ  . PHE B 1 24  ? -24.935 -5.060  146.785 1.00 10.89  ? 24  PHE B CZ  1 
ATOM 1348 N N   . PRO B 1 25  ? -22.872 1.782   148.562 1.00 11.77  ? 25  PRO B N   1 
ATOM 1349 C CA  . PRO B 1 25  ? -23.008 3.061   149.272 1.00 11.77  ? 25  PRO B CA  1 
ATOM 1350 C C   . PRO B 1 25  ? -24.321 3.162   150.037 1.00 11.77  ? 25  PRO B C   1 
ATOM 1351 O O   . PRO B 1 25  ? -25.233 2.344   149.901 1.00 11.77  ? 25  PRO B O   1 
ATOM 1352 C CB  . PRO B 1 25  ? -22.928 4.112   148.156 1.00 11.77  ? 25  PRO B CB  1 
ATOM 1353 C CG  . PRO B 1 25  ? -22.351 3.405   146.982 1.00 11.77  ? 25  PRO B CG  1 
ATOM 1354 C CD  . PRO B 1 25  ? -22.769 1.978   147.107 1.00 11.77  ? 25  PRO B CD  1 
ATOM 1355 N N   . SER B 1 26  ? -24.402 4.208   150.857 1.00 12.58  ? 26  SER B N   1 
ATOM 1356 C CA  . SER B 1 26  ? -25.626 4.542   151.570 1.00 12.58  ? 26  SER B CA  1 
ATOM 1357 C C   . SER B 1 26  ? -26.733 4.972   150.608 1.00 12.58  ? 26  SER B C   1 
ATOM 1358 O O   . SER B 1 26  ? -26.492 5.332   149.452 1.00 12.58  ? 26  SER B O   1 
ATOM 1359 C CB  . SER B 1 26  ? -25.362 5.654   152.585 1.00 12.58  ? 26  SER B CB  1 
ATOM 1360 O OG  . SER B 1 26  ? -25.264 6.914   151.945 1.00 12.58  ? 26  SER B OG  1 
ATOM 1361 N N   . VAL B 1 27  ? -27.968 4.926   151.112 1.00 13.46  ? 27  VAL B N   1 
ATOM 1362 C CA  . VAL B 1 27  ? -29.120 5.386   150.339 1.00 13.46  ? 27  VAL B CA  1 
ATOM 1363 C C   . VAL B 1 27  ? -28.936 6.842   149.924 1.00 13.46  ? 27  VAL B C   1 
ATOM 1364 O O   . VAL B 1 27  ? -29.219 7.222   148.784 1.00 13.46  ? 27  VAL B O   1 
ATOM 1365 C CB  . VAL B 1 27  ? -30.420 5.192   151.141 1.00 13.46  ? 27  VAL B CB  1 
ATOM 1366 C CG1 . VAL B 1 27  ? -31.609 5.764   150.385 1.00 13.46  ? 27  VAL B CG1 1 
ATOM 1367 C CG2 . VAL B 1 27  ? -30.646 3.720   151.445 1.00 13.46  ? 27  VAL B CG2 1 
ATOM 1368 N N   . ARG B 1 28  ? -28.510 7.675   150.861 1.00 15.23  ? 28  ARG B N   1 
ATOM 1369 C CA  . ARG B 1 28  ? -28.282 9.092   150.509 1.00 15.23  ? 28  ARG B CA  1 
ATOM 1370 C C   . ARG B 1 28  ? -27.303 9.144   149.336 1.00 15.23  ? 28  ARG B C   1 
ATOM 1371 O O   . ARG B 1 28  ? -27.647 9.758   148.320 1.00 15.23  ? 28  ARG B O   1 
ATOM 1372 C CB  . ARG B 1 28  ? -27.782 9.861   151.730 1.00 15.23  ? 28  ARG B CB  1 
ATOM 1373 C CG  . ARG B 1 28  ? -27.904 11.372  151.610 1.00 15.23  ? 28  ARG B CG  1 
ATOM 1374 C CD  . ARG B 1 28  ? -29.313 11.774  151.225 1.00 15.23  ? 28  ARG B CD  1 
ATOM 1375 N NE  . ARG B 1 28  ? -29.472 11.873  149.783 1.00 15.23  ? 28  ARG B NE  1 
ATOM 1376 C CZ  . ARG B 1 28  ? -30.633 12.051  149.168 1.00 15.23  ? 28  ARG B CZ  1 
ATOM 1377 N NH1 . ARG B 1 28  ? -31.748 12.135  149.873 1.00 15.23  ? 28  ARG B NH1 1 
ATOM 1378 N NH2 . ARG B 1 28  ? -30.677 12.135  147.851 1.00 15.23  ? 28  ARG B NH2 1 
ATOM 1379 N N   . ASP B 1 29  ? -26.139 8.507   149.461 1.00 14.18  ? 29  ASP B N   1 
ATOM 1380 C CA  . ASP B 1 29  ? -25.137 8.586   148.401 1.00 14.18  ? 29  ASP B CA  1 
ATOM 1381 C C   . ASP B 1 29  ? -25.671 8.117   147.052 1.00 14.18  ? 29  ASP B C   1 
ATOM 1382 O O   . ASP B 1 29  ? -25.421 8.757   146.024 1.00 14.18  ? 29  ASP B O   1 
ATOM 1383 C CB  . ASP B 1 29  ? -23.911 7.761   148.790 1.00 14.18  ? 29  ASP B CB  1 
ATOM 1384 C CG  . ASP B 1 29  ? -23.149 8.361   149.955 1.00 14.18  ? 29  ASP B CG  1 
ATOM 1385 O OD1 . ASP B 1 29  ? -23.318 9.570   150.220 1.00 14.18  ? 29  ASP B OD1 1 
ATOM 1386 O OD2 . ASP B 1 29  ? -22.381 7.623   150.605 1.00 14.18  ? 29  ASP B OD2 1 
ATOM 1387 N N   . LEU B 1 30  ? -26.446 7.034   147.038 1.00 12.16  ? 30  LEU B N   1 
ATOM 1388 C CA  . LEU B 1 30  ? -26.998 6.543   145.778 1.00 12.16  ? 30  LEU B CA  1 
ATOM 1389 C C   . LEU B 1 30  ? -28.061 7.473   145.208 1.00 12.16  ? 30  LEU B C   1 
ATOM 1390 O O   . LEU B 1 30  ? -28.114 7.682   143.993 1.00 12.16  ? 30  LEU B O   1 
ATOM 1391 C CB  . LEU B 1 30  ? -27.566 5.138   145.969 1.00 12.16  ? 30  LEU B CB  1 
ATOM 1392 C CG  . LEU B 1 30  ? -26.513 4.045   146.171 1.00 12.16  ? 30  LEU B CG  1 
ATOM 1393 C CD1 . LEU B 1 30  ? -27.145 2.787   146.733 1.00 12.16  ? 30  LEU B CD1 1 
ATOM 1394 C CD2 . LEU B 1 30  ? -25.798 3.745   144.862 1.00 12.16  ? 30  LEU B CD2 1 
ATOM 1395 N N   . LEU B 1 31  ? -28.928 8.026   146.053 1.00 13.45  ? 31  LEU B N   1 
ATOM 1396 C CA  . LEU B 1 31  ? -29.918 8.974   145.554 1.00 13.45  ? 31  LEU B CA  1 
ATOM 1397 C C   . LEU B 1 31  ? -29.276 10.272  145.072 1.00 13.45  ? 31  LEU B C   1 
ATOM 1398 O O   . LEU B 1 31  ? -29.683 10.818  144.039 1.00 13.45  ? 31  LEU B O   1 
ATOM 1399 C CB  . LEU B 1 31  ? -30.959 9.265   146.636 1.00 13.45  ? 31  LEU B CB  1 
ATOM 1400 C CG  . LEU B 1 31  ? -31.893 8.110   147.011 1.00 13.45  ? 31  LEU B CG  1 
ATOM 1401 C CD1 . LEU B 1 31  ? -32.835 8.528   148.126 1.00 13.45  ? 31  LEU B CD1 1 
ATOM 1402 C CD2 . LEU B 1 31  ? -32.684 7.630   145.802 1.00 13.45  ? 31  LEU B CD2 1 
ATOM 1403 N N   . ASP B 1 32  ? -28.250 10.765  145.773 1.00 13.95  ? 32  ASP B N   1 
ATOM 1404 C CA  . ASP B 1 32  ? -27.465 11.876  145.242 1.00 13.95  ? 32  ASP B CA  1 
ATOM 1405 C C   . ASP B 1 32  ? -26.866 11.549  143.879 1.00 13.95  ? 32  ASP B C   1 
ATOM 1406 O O   . ASP B 1 32  ? -26.954 12.353  142.944 1.00 13.95  ? 32  ASP B O   1 
ATOM 1407 C CB  . ASP B 1 32  ? -26.360 12.246  146.232 1.00 13.95  ? 32  ASP B CB  1 
ATOM 1408 C CG  . ASP B 1 32  ? -26.893 12.927  147.473 1.00 13.95  ? 32  ASP B CG  1 
ATOM 1409 O OD1 . ASP B 1 32  ? -28.124 13.106  147.570 1.00 13.95  ? 32  ASP B OD1 1 
ATOM 1410 O OD2 . ASP B 1 32  ? -26.083 13.280  148.355 1.00 13.95  ? 32  ASP B OD2 1 
ATOM 1411 N N   . THR B 1 33  ? -26.239 10.378  143.748 1.00 13.16  ? 33  THR B N   1 
ATOM 1412 C CA  . THR B 1 33  ? -25.603 10.020  142.484 1.00 13.16  ? 33  THR B CA  1 
ATOM 1413 C C   . THR B 1 33  ? -26.627 9.920   141.360 1.00 13.16  ? 33  THR B C   1 
ATOM 1414 O O   . THR B 1 33  ? -26.423 10.452  140.263 1.00 13.16  ? 33  THR B O   1 
ATOM 1415 C CB  . THR B 1 33  ? -24.846 8.701   142.637 1.00 13.16  ? 33  THR B CB  1 
ATOM 1416 O OG1 . THR B 1 33  ? -23.888 8.815   143.696 1.00 13.16  ? 33  THR B OG1 1 
ATOM 1417 C CG2 . THR B 1 33  ? -24.124 8.338   141.346 1.00 13.16  ? 33  THR B CG2 1 
ATOM 1418 N N   . ALA B 1 34  ? -27.737 9.228   141.621 1.00 13.92  ? 34  ALA B N   1 
ATOM 1419 C CA  . ALA B 1 34  ? -28.794 9.099   140.628 1.00 13.92  ? 34  ALA B CA  1 
ATOM 1420 C C   . ALA B 1 34  ? -29.357 10.450  140.218 1.00 13.92  ? 34  ALA B C   1 
ATOM 1421 O O   . ALA B 1 34  ? -29.513 10.723  139.024 1.00 13.92  ? 34  ALA B O   1 
ATOM 1422 C CB  . ALA B 1 34  ? -29.909 8.203   141.167 1.00 13.92  ? 34  ALA B CB  1 
ATOM 1423 N N   . SER B 1 35  ? -29.597 11.344  141.180 1.00 15.44  ? 35  SER B N   1 
ATOM 1424 C CA  . SER B 1 35  ? -30.157 12.638  140.821 1.00 15.44  ? 35  SER B CA  1 
ATOM 1425 C C   . SER B 1 35  ? -29.172 13.482  140.027 1.00 15.44  ? 35  SER B C   1 
ATOM 1426 O O   . SER B 1 35  ? -29.489 13.890  138.905 1.00 15.44  ? 35  SER B O   1 
ATOM 1427 C CB  . SER B 1 35  ? -30.583 13.387  142.082 1.00 15.44  ? 35  SER B CB  1 
ATOM 1428 O OG  . SER B 1 35  ? -31.420 14.486  141.767 1.00 15.44  ? 35  SER B OG  1 
ATOM 1429 N N   . ALA B 1 36  ? -27.917 13.525  140.465 1.00 14.49  ? 36  ALA B N   1 
ATOM 1430 C CA  . ALA B 1 36  ? -26.904 14.311  139.770 1.00 14.49  ? 36  ALA B CA  1 
ATOM 1431 C C   . ALA B 1 36  ? -26.658 13.805  138.355 1.00 14.49  ? 36  ALA B C   1 
ATOM 1432 O O   . ALA B 1 36  ? -26.637 14.597  137.405 1.00 14.49  ? 36  ALA B O   1 
ATOM 1433 C CB  . ALA B 1 36  ? -25.605 14.302  140.574 1.00 14.49  ? 36  ALA B CB  1 
ATOM 1434 N N   . LEU B 1 37  ? -26.461 12.500  138.181 1.00 14.24  ? 37  LEU B N   1 
ATOM 1435 C CA  . LEU B 1 37  ? -26.172 12.016  136.837 1.00 14.24  ? 37  LEU B CA  1 
ATOM 1436 C C   . LEU B 1 37  ? -27.410 12.018  135.940 1.00 14.24  ? 37  LEU B C   1 
ATOM 1437 O O   . LEU B 1 37  ? -27.324 12.436  134.780 1.00 14.24  ? 37  LEU B O   1 
ATOM 1438 C CB  . LEU B 1 37  ? -25.562 10.615  136.912 1.00 14.24  ? 37  LEU B CB  1 
ATOM 1439 C CG  . LEU B 1 37  ? -24.062 10.568  137.227 1.00 14.24  ? 37  LEU B CG  1 
ATOM 1440 C CD1 . LEU B 1 37  ? -23.746 11.199  138.576 1.00 14.24  ? 37  LEU B CD1 1 
ATOM 1441 C CD2 . LEU B 1 37  ? -23.555 9.137   137.178 1.00 14.24  ? 37  LEU B CD2 1 
ATOM 1442 N N   . TYR B 1 38  ? -28.568 11.563  136.436 1.00 13.93  ? 38  TYR B N   1 
ATOM 1443 C CA  . TYR B 1 38  ? -29.626 11.122  135.539 1.00 13.93  ? 38  TYR B CA  1 
ATOM 1444 C C   . TYR B 1 38  ? -30.995 11.738  135.824 1.00 13.93  ? 38  TYR B C   1 
ATOM 1445 O O   . TYR B 1 38  ? -31.980 11.281  135.233 1.00 13.93  ? 38  TYR B O   1 
ATOM 1446 C CB  . TYR B 1 38  ? -29.737 9.594   135.594 1.00 13.93  ? 38  TYR B CB  1 
ATOM 1447 C CG  . TYR B 1 38  ? -28.464 8.882   135.188 1.00 13.93  ? 38  TYR B CG  1 
ATOM 1448 C CD1 . TYR B 1 38  ? -27.986 8.958   133.888 1.00 13.93  ? 38  TYR B CD1 1 
ATOM 1449 C CD2 . TYR B 1 38  ? -27.745 8.128   136.106 1.00 13.93  ? 38  TYR B CD2 1 
ATOM 1450 C CE1 . TYR B 1 38  ? -26.828 8.302   133.514 1.00 13.93  ? 38  TYR B CE1 1 
ATOM 1451 C CE2 . TYR B 1 38  ? -26.587 7.469   135.741 1.00 13.93  ? 38  TYR B CE2 1 
ATOM 1452 C CZ  . TYR B 1 38  ? -26.130 7.563   134.444 1.00 13.93  ? 38  TYR B CZ  1 
ATOM 1453 O OH  . TYR B 1 38  ? -24.967 6.927   134.081 1.00 13.93  ? 38  TYR B OH  1 
ATOM 1454 N N   . ARG B 1 39  ? -31.061 12.778  136.653 1.00 17.35  ? 39  ARG B N   1 
ATOM 1455 C CA  . ARG B 1 39  ? -32.356 13.384  137.051 1.00 17.35  ? 39  ARG B CA  1 
ATOM 1456 C C   . ARG B 1 39  ? -33.114 13.862  135.828 1.00 17.35  ? 39  ARG B C   1 
ATOM 1457 O O   . ARG B 1 39  ? -34.307 13.614  135.757 1.00 17.35  ? 39  ARG B O   1 
ATOM 1458 C CB  . ARG B 1 39  ? -32.204 14.621  137.931 1.00 17.35  ? 39  ARG B CB  1 
ATOM 1459 C CG  . ARG B 1 39  ? -33.511 15.382  138.100 1.00 17.35  ? 39  ARG B CG  1 
ATOM 1460 C CD  . ARG B 1 39  ? -33.613 16.082  139.433 1.00 17.35  ? 39  ARG B CD  1 
ATOM 1461 N NE  . ARG B 1 39  ? -32.734 17.235  139.503 1.00 17.35  ? 39  ARG B NE  1 
ATOM 1462 C CZ  . ARG B 1 39  ? -32.636 18.039  140.551 1.00 17.35  ? 39  ARG B CZ  1 
ATOM 1463 N NH1 . ARG B 1 39  ? -33.364 17.816  141.632 1.00 17.35  ? 39  ARG B NH1 1 
ATOM 1464 N NH2 . ARG B 1 39  ? -31.806 19.066  140.517 1.00 17.35  ? 39  ARG B NH2 1 
ATOM 1465 N N   . GLU B 1 40  ? -32.456 14.571  134.933 1.00 18.12  ? 40  GLU B N   1 
ATOM 1466 C CA  . GLU B 1 40  ? -33.131 15.173  133.785 1.00 18.12  ? 40  GLU B CA  1 
ATOM 1467 C C   . GLU B 1 40  ? -33.664 14.118  132.819 1.00 18.12  ? 40  GLU B C   1 
ATOM 1468 O O   . GLU B 1 40  ? -34.693 14.338  132.169 1.00 18.12  ? 40  GLU B O   1 
ATOM 1469 C CB  . GLU B 1 40  ? -32.172 16.120  133.061 1.00 18.12  ? 40  GLU B CB  1 
ATOM 1470 C CG  . GLU B 1 40  ? -31.772 17.332  133.893 1.00 18.12  ? 40  GLU B CG  1 
ATOM 1471 C CD  . GLU B 1 40  ? -32.930 18.274  134.164 1.00 18.12  ? 40  GLU B CD  1 
ATOM 1472 O OE1 . GLU B 1 40  ? -33.777 18.458  133.264 1.00 18.12  ? 40  GLU B OE1 1 
ATOM 1473 O OE2 . GLU B 1 40  ? -33.011 18.804  135.292 1.00 18.12  ? 40  GLU B OE2 1 
ATOM 1474 N N   . ALA B 1 41  ? -32.991 12.974  132.718 1.00 15.56  ? 41  ALA B N   1 
ATOM 1475 C CA  . ALA B 1 41  ? -33.488 11.848  131.927 1.00 15.56  ? 41  ALA B CA  1 
ATOM 1476 C C   . ALA B 1 41  ? -34.642 11.125  132.619 1.00 15.56  ? 41  ALA B C   1 
ATOM 1477 O O   . ALA B 1 41  ? -35.622 10.749  131.969 1.00 15.56  ? 41  ALA B O   1 
ATOM 1478 C CB  . ALA B 1 41  ? -32.352 10.869  131.638 1.00 15.56  ? 41  ALA B CB  1 
ATOM 1479 N N   . LEU B 1 42  ? -34.534 10.919  133.931 1.00 14.27  ? 42  LEU B N   1 
ATOM 1480 C CA  . LEU B 1 42  ? -35.547 10.172  134.674 1.00 14.27  ? 42  LEU B CA  1 
ATOM 1481 C C   . LEU B 1 42  ? -36.866 10.934  134.740 1.00 14.27  ? 42  LEU B C   1 
ATOM 1482 O O   . LEU B 1 42  ? -37.941 10.331  134.649 1.00 14.27  ? 42  LEU B O   1 
ATOM 1483 C CB  . LEU B 1 42  ? -35.034 9.852   136.078 1.00 14.27  ? 42  LEU B CB  1 
ATOM 1484 C CG  . LEU B 1 42  ? -33.828 8.912   136.131 1.00 14.27  ? 42  LEU B CG  1 
ATOM 1485 C CD1 . LEU B 1 42  ? -33.313 8.780   137.555 1.00 14.27  ? 42  LEU B CD1 1 
ATOM 1486 C CD2 . LEU B 1 42  ? -34.169 7.542   135.558 1.00 14.27  ? 42  LEU B CD2 1 
ATOM 1487 N N   . GLU B 1 43  ? -36.804 12.253  134.906 1.00 17.17  ? 43  GLU B N   1 
ATOM 1488 C CA  . GLU B 1 43  ? -37.994 13.092  134.832 1.00 17.17  ? 43  GLU B CA  1 
ATOM 1489 C C   . GLU B 1 43  ? -38.542 13.226  133.415 1.00 17.17  ? 43  GLU B C   1 
ATOM 1490 O O   . GLU B 1 43  ? -39.645 13.754  133.253 1.00 17.17  ? 43  GLU B O   1 
ATOM 1491 C CB  . GLU B 1 43  ? -37.671 14.488  135.367 1.00 17.17  ? 43  GLU B CB  1 
ATOM 1492 C CG  . GLU B 1 43  ? -37.380 14.553  136.855 1.00 17.17  ? 43  GLU B CG  1 
ATOM 1493 C CD  . GLU B 1 43  ? -37.313 15.982  137.362 1.00 17.17  ? 43  GLU B CD  1 
ATOM 1494 O OE1 . GLU B 1 43  ? -37.280 16.910  136.525 1.00 17.17  ? 43  GLU B OE1 1 
ATOM 1495 O OE2 . GLU B 1 43  ? -37.282 16.182  138.591 1.00 17.17  ? 43  GLU B OE2 1 
ATOM 1496 N N   . SER B 1 44  ? -37.812 12.777  132.397 1.00 17.03  ? 44  SER B N   1 
ATOM 1497 C CA  . SER B 1 44  ? -38.221 13.006  131.022 1.00 17.03  ? 44  SER B CA  1 
ATOM 1498 C C   . SER B 1 44  ? -39.456 12.166  130.681 1.00 17.03  ? 44  SER B C   1 
ATOM 1499 O O   . SER B 1 44  ? -39.652 11.083  131.238 1.00 17.03  ? 44  SER B O   1 
ATOM 1500 C CB  . SER B 1 44  ? -37.083 12.665  130.065 1.00 17.03  ? 44  SER B CB  1 
ATOM 1501 O OG  . SER B 1 44  ? -37.467 12.848  128.716 1.00 17.03  ? 44  SER B OG  1 
ATOM 1502 N N   . PRO B 1 45  ? -40.312 12.650  129.773 1.00 17.33  ? 45  PRO B N   1 
ATOM 1503 C CA  . PRO B 1 45  ? -41.486 11.858  129.370 1.00 17.33  ? 45  PRO B CA  1 
ATOM 1504 C C   . PRO B 1 45  ? -41.172 10.684  128.453 1.00 17.33  ? 45  PRO B C   1 
ATOM 1505 O O   . PRO B 1 45  ? -42.040 9.825   128.271 1.00 17.33  ? 45  PRO B O   1 
ATOM 1506 C CB  . PRO B 1 45  ? -42.372 12.893  128.666 1.00 17.33  ? 45  PRO B CB  1 
ATOM 1507 C CG  . PRO B 1 45  ? -41.396 13.839  128.071 1.00 17.33  ? 45  PRO B CG  1 
ATOM 1508 C CD  . PRO B 1 45  ? -40.302 13.967  129.109 1.00 17.33  ? 45  PRO B CD  1 
ATOM 1509 N N   . GLU B 1 46  ? -40.000 10.638  127.835 1.00 17.47  ? 46  GLU B N   1 
ATOM 1510 C CA  . GLU B 1 46  ? -39.617 9.481   127.039 1.00 17.47  ? 46  GLU B CA  1 
ATOM 1511 C C   . GLU B 1 46  ? -39.056 8.384   127.936 1.00 17.47  ? 46  GLU B C   1 
ATOM 1512 O O   . GLU B 1 46  ? -38.493 8.653   129.001 1.00 17.47  ? 46  GLU B O   1 
ATOM 1513 C CB  . GLU B 1 46  ? -38.582 9.876   125.984 1.00 17.47  ? 46  GLU B CB  1 
ATOM 1514 C CG  . GLU B 1 46  ? -39.001 11.043  125.102 1.00 17.47  ? 46  GLU B CG  1 
ATOM 1515 C CD  . GLU B 1 46  ? -40.067 10.657  124.095 1.00 17.47  ? 46  GLU B CD  1 
ATOM 1516 O OE1 . GLU B 1 46  ? -39.945 9.574   123.487 1.00 17.47  ? 46  GLU B OE1 1 
ATOM 1517 O OE2 . GLU B 1 46  ? -41.026 11.435  123.914 1.00 17.47  ? 46  GLU B OE2 1 
ATOM 1518 N N   . HIS B 1 47  ? -39.213 7.133   127.500 1.00 15.90  ? 47  HIS B N   1 
ATOM 1519 C CA  . HIS B 1 47  ? -38.597 6.008   128.203 1.00 15.90  ? 47  HIS B CA  1 
ATOM 1520 C C   . HIS B 1 47  ? -37.184 5.868   127.657 1.00 15.90  ? 47  HIS B C   1 
ATOM 1521 O O   . HIS B 1 47  ? -36.976 5.268   126.599 1.00 15.90  ? 47  HIS B O   1 
ATOM 1522 C CB  . HIS B 1 47  ? -39.358 4.704   127.981 1.00 15.90  ? 47  HIS B CB  1 
ATOM 1523 C CG  . HIS B 1 47  ? -40.849 4.831   128.011 1.00 15.90  ? 47  HIS B CG  1 
ATOM 1524 N ND1 . HIS B 1 47  ? -41.598 4.543   129.131 1.00 15.90  ? 47  HIS B ND1 1 
ATOM 1525 C CD2 . HIS B 1 47  ? -41.735 5.167   127.044 1.00 15.90  ? 47  HIS B CD2 1 
ATOM 1526 C CE1 . HIS B 1 47  ? -42.879 4.717   128.859 1.00 15.90  ? 47  HIS B CE1 1 
ATOM 1527 N NE2 . HIS B 1 47  ? -42.989 5.095   127.598 1.00 15.90  ? 47  HIS B NE2 1 
ATOM 1528 N N   . CYS B 1 48  ? -36.200 6.423   128.363 1.00 15.23  ? 48  CYS B N   1 
ATOM 1529 C CA  . CYS B 1 48  ? -34.852 6.413   127.809 1.00 15.23  ? 48  CYS B CA  1 
ATOM 1530 C C   . CYS B 1 48  ? -34.345 4.985   127.680 1.00 15.23  ? 48  CYS B C   1 
ATOM 1531 O O   . CYS B 1 48  ? -33.753 4.613   126.661 1.00 15.23  ? 48  CYS B O   1 
ATOM 1532 C CB  . CYS B 1 48  ? -33.921 7.249   128.687 1.00 15.23  ? 48  CYS B CB  1 
ATOM 1533 S SG  . CYS B 1 48  ? -34.547 8.903   129.046 1.00 15.23  ? 48  CYS B SG  1 
ATOM 1534 N N   . SER B 1 49  ? -34.573 4.174   128.706 1.00 13.25  ? 49  SER B N   1 
ATOM 1535 C CA  . SER B 1 49  ? -34.100 2.798   128.741 1.00 13.25  ? 49  SER B CA  1 
ATOM 1536 C C   . SER B 1 49  ? -34.935 2.042   129.766 1.00 13.25  ? 49  SER B C   1 
ATOM 1537 O O   . SER B 1 49  ? -35.637 2.657   130.581 1.00 13.25  ? 49  SER B O   1 
ATOM 1538 C CB  . SER B 1 49  ? -32.601 2.732   129.087 1.00 13.25  ? 49  SER B CB  1 
ATOM 1539 O OG  . SER B 1 49  ? -32.390 2.863   130.480 1.00 13.25  ? 49  SER B OG  1 
ATOM 1540 N N   . PRO B 1 50  ? -34.888 0.709   129.754 1.00 12.38  ? 50  PRO B N   1 
ATOM 1541 C CA  . PRO B 1 50  ? -35.580 -0.052  130.808 1.00 12.38  ? 50  PRO B CA  1 
ATOM 1542 C C   . PRO B 1 50  ? -34.988 0.176   132.190 1.00 12.38  ? 50  PRO B C   1 
ATOM 1543 O O   . PRO B 1 50  ? -35.711 0.136   133.196 1.00 12.38  ? 50  PRO B O   1 
ATOM 1544 C CB  . PRO B 1 50  ? -35.431 -1.510  130.345 1.00 12.38  ? 50  PRO B CB  1 
ATOM 1545 C CG  . PRO B 1 50  ? -34.236 -1.511  129.465 1.00 12.38  ? 50  PRO B CG  1 
ATOM 1546 C CD  . PRO B 1 50  ? -34.254 -0.181  128.767 1.00 12.38  ? 50  PRO B CD  1 
ATOM 1547 N N   . HIS B 1 51  ? -33.665 0.376   132.227 1.00 11.79  ? 51  HIS B N   1 
ATOM 1548 C CA  . HIS B 1 51  ? -32.924 0.630   133.487 1.00 11.79  ? 51  HIS B CA  1 
ATOM 1549 C C   . HIS B 1 51  ? -33.407 1.943   134.093 1.00 11.79  ? 51  HIS B C   1 
ATOM 1550 O O   . HIS B 1 51  ? -33.591 1.957   135.295 1.00 11.79  ? 51  HIS B O   1 
ATOM 1551 C CB  . HIS B 1 51  ? -31.411 0.658   133.238 1.00 11.79  ? 51  HIS B CB  1 
ATOM 1552 C CG  . HIS B 1 51  ? -30.810 -0.691  133.027 1.00 11.79  ? 51  HIS B CG  1 
ATOM 1553 N ND1 . HIS B 1 51  ? -30.165 -1.376  134.038 1.00 11.79  ? 51  HIS B ND1 1 
ATOM 1554 C CD2 . HIS B 1 51  ? -30.752 -1.479  131.932 1.00 11.79  ? 51  HIS B CD2 1 
ATOM 1555 C CE1 . HIS B 1 51  ? -29.733 -2.532  133.573 1.00 11.79  ? 51  HIS B CE1 1 
ATOM 1556 N NE2 . HIS B 1 51  ? -30.076 -2.618  132.284 1.00 11.79  ? 51  HIS B NE2 1 
ATOM 1557 N N   . HIS B 1 52  ? -33.649 2.955   133.249 1.00 12.84  ? 52  HIS B N   1 
ATOM 1558 C CA  . HIS B 1 52  ? -34.127 4.298   133.661 1.00 12.84  ? 52  HIS B CA  1 
ATOM 1559 C C   . HIS B 1 52  ? -35.495 4.143   134.292 1.00 12.84  ? 52  HIS B C   1 
ATOM 1560 O O   . HIS B 1 52  ? -35.742 4.785   135.303 1.00 12.84  ? 52  HIS B O   1 
ATOM 1561 C CB  . HIS B 1 52  ? -34.221 5.232   132.454 1.00 12.84  ? 52  HIS B CB  1 
ATOM 1562 C CG  . HIS B 1 52  ? -33.013 6.066   132.205 1.00 12.84  ? 52  HIS B CG  1 
ATOM 1563 N ND1 . HIS B 1 52  ? -32.648 7.096   133.044 1.00 12.84  ? 52  HIS B ND1 1 
ATOM 1564 C CD2 . HIS B 1 52  ? -32.111 6.056   131.202 1.00 12.84  ? 52  HIS B CD2 1 
ATOM 1565 C CE1 . HIS B 1 52  ? -31.560 7.671   132.579 1.00 12.84  ? 52  HIS B CE1 1 
ATOM 1566 N NE2 . HIS B 1 52  ? -31.213 7.054   131.449 1.00 12.84  ? 52  HIS B NE2 1 
ATOM 1567 N N   . THR B 1 53  ? -36.357 3.357   133.685 1.00 12.50  ? 53  THR B N   1 
ATOM 1568 C CA  . THR B 1 53  ? -37.724 3.050   134.178 1.00 12.50  ? 53  THR B CA  1 
ATOM 1569 C C   . THR B 1 53  ? -37.597 2.312   135.509 1.00 12.50  ? 53  THR B C   1 
ATOM 1570 O O   . THR B 1 53  ? -38.306 2.701   136.465 1.00 12.50  ? 53  THR B O   1 
ATOM 1571 C CB  . THR B 1 53  ? -38.511 2.238   133.142 1.00 12.50  ? 53  THR B CB  1 
ATOM 1572 O OG1 . THR B 1 53  ? -38.597 3.013   131.947 1.00 12.50  ? 53  THR B OG1 1 
ATOM 1573 C CG2 . THR B 1 53  ? -39.900 1.871   133.616 1.00 12.50  ? 53  THR B CG2 1 
ATOM 1574 N N   . ALA B 1 54  ? -36.707 1.317   135.590 1.00 12.20  ? 54  ALA B N   1 
ATOM 1575 C CA  . ALA B 1 54  ? -36.503 0.516   136.817 1.00 12.20  ? 54  ALA B CA  1 
ATOM 1576 C C   . ALA B 1 54  ? -36.089 1.460   137.943 1.00 12.20  ? 54  ALA B C   1 
ATOM 1577 O O   . ALA B 1 54  ? -36.653 1.336   139.043 1.00 12.20  ? 54  ALA B O   1 
ATOM 1578 C CB  . ALA B 1 54  ? -35.464 -0.548  136.564 1.00 12.20  ? 54  ALA B CB  1 
ATOM 1579 N N   . LEU B 1 55  ? -35.179 2.395   137.665 1.00 12.46  ? 55  LEU B N   1 
ATOM 1580 C CA  . LEU B 1 55  ? -34.668 3.365   138.663 1.00 12.46  ? 55  LEU B CA  1 
ATOM 1581 C C   . LEU B 1 55  ? -35.838 4.216   139.149 1.00 12.46  ? 55  LEU B C   1 
ATOM 1582 O O   . LEU B 1 55  ? -35.999 4.305   140.359 1.00 12.46  ? 55  LEU B O   1 
ATOM 1583 C CB  . LEU B 1 55  ? -33.574 4.218   138.012 1.00 12.46  ? 55  LEU B CB  1 
ATOM 1584 C CG  . LEU B 1 55  ? -32.225 3.522   137.838 1.00 12.46  ? 55  LEU B CG  1 
ATOM 1585 C CD1 . LEU B 1 55  ? -31.455 4.105   136.665 1.00 12.46  ? 55  LEU B CD1 1 
ATOM 1586 C CD2 . LEU B 1 55  ? -31.401 3.603   139.115 1.00 12.46  ? 55  LEU B CD2 1 
ATOM 1587 N N   . ARG B 1 56  ? -36.653 4.760   138.242 1.00 13.38  ? 56  ARG B N   1 
ATOM 1588 C CA  . ARG B 1 56  ? -37.847 5.562   138.623 1.00 13.38  ? 56  ARG B CA  1 
ATOM 1589 C C   . ARG B 1 56  ? -38.702 4.723   139.570 1.00 13.38  ? 56  ARG B C   1 
ATOM 1590 O O   . ARG B 1 56  ? -39.031 5.226   140.665 1.00 13.38  ? 56  ARG B O   1 
ATOM 1591 C CB  . ARG B 1 56  ? -38.667 5.951   137.391 1.00 13.38  ? 56  ARG B CB  1 
ATOM 1592 C CG  . ARG B 1 56  ? -37.927 6.843   136.408 1.00 13.38  ? 56  ARG B CG  1 
ATOM 1593 C CD  . ARG B 1 56  ? -38.419 6.683   134.983 1.00 13.38  ? 56  ARG B CD  1 
ATOM 1594 N NE  . ARG B 1 56  ? -37.460 7.234   134.037 1.00 13.38  ? 56  ARG B NE  1 
ATOM 1595 C CZ  . ARG B 1 56  ? -37.493 7.055   132.721 1.00 13.38  ? 56  ARG B CZ  1 
ATOM 1596 N NH1 . ARG B 1 56  ? -38.441 6.318   132.167 1.00 13.38  ? 56  ARG B NH1 1 
ATOM 1597 N NH2 . ARG B 1 56  ? -36.565 7.610   131.962 1.00 13.38  ? 56  ARG B NH2 1 
ATOM 1598 N N   . GLN B 1 57  ? -39.008 3.479   139.193 1.00 13.43  ? 57  GLN B N   1 
ATOM 1599 C CA  . GLN B 1 57  ? -39.870 2.583   140.005 1.00 13.43  ? 57  GLN B CA  1 
ATOM 1600 C C   . GLN B 1 57  ? -39.277 2.450   141.407 1.00 13.43  ? 57  GLN B C   1 
ATOM 1601 O O   . GLN B 1 57  ? -40.011 2.721   142.383 1.00 13.43  ? 57  GLN B O   1 
ATOM 1602 C CB  . GLN B 1 57  ? -39.978 1.218   139.329 1.00 13.43  ? 57  GLN B CB  1 
ATOM 1603 C CG  . GLN B 1 57  ? -40.843 1.225   138.077 1.00 13.43  ? 57  GLN B CG  1 
ATOM 1604 C CD  . GLN B 1 57  ? -42.317 1.194   138.397 1.00 13.43  ? 57  GLN B CD  1 
ATOM 1605 O OE1 . GLN B 1 57  ? -42.723 1.041   139.546 1.00 13.43  ? 57  GLN B OE1 1 
ATOM 1606 N NE2 . GLN B 1 57  ? -43.136 1.333   137.368 1.00 13.43  ? 57  GLN B NE2 1 
ATOM 1607 N N   . ALA B 1 58  ? -37.994 2.099   141.512 1.00 13.15  ? 58  ALA B N   1 
ATOM 1608 C CA  . ALA B 1 58  ? -37.318 1.879   142.809 1.00 13.15  ? 58  ALA B CA  1 
ATOM 1609 C C   . ALA B 1 58  ? -37.389 3.162   143.635 1.00 13.15  ? 58  ALA B C   1 
ATOM 1610 O O   . ALA B 1 58  ? -37.718 3.062   144.818 1.00 13.15  ? 58  ALA B O   1 
ATOM 1611 C CB  . ALA B 1 58  ? -35.894 1.455   142.563 1.00 13.15  ? 58  ALA B CB  1 
ATOM 1612 N N   . ILE B 1 59  ? -37.107 4.314   143.030 1.00 14.04  ? 59  ILE B N   1 
ATOM 1613 C CA  . ILE B 1 59  ? -37.123 5.635   143.718 1.00 14.04  ? 59  ILE B CA  1 
ATOM 1614 C C   . ILE B 1 59  ? -38.516 5.839   144.310 1.00 14.04  ? 59  ILE B C   1 
ATOM 1615 O O   . ILE B 1 59  ? -38.596 6.105   145.518 1.00 14.04  ? 59  ILE B O   1 
ATOM 1616 C CB  . ILE B 1 59  ? -36.744 6.757   142.729 1.00 14.04  ? 59  ILE B CB  1 
ATOM 1617 C CG1 . ILE B 1 59  ? -35.315 6.597   142.207 1.00 14.04  ? 59  ILE B CG1 1 
ATOM 1618 C CG2 . ILE B 1 59  ? -36.960 8.125   143.352 1.00 14.04  ? 59  ILE B CG2 1 
ATOM 1619 C CD1 . ILE B 1 59  ? -35.068 7.294   140.891 1.00 14.04  ? 59  ILE B CD1 1 
ATOM 1620 N N   . LEU B 1 60  ? -39.568 5.667   143.507 1.00 14.39  ? 60  LEU B N   1 
ATOM 1621 C CA  . LEU B 1 60  ? -40.968 5.873   143.967 1.00 14.39  ? 60  LEU B CA  1 
ATOM 1622 C C   . LEU B 1 60  ? -41.258 4.919   145.130 1.00 14.39  ? 60  LEU B C   1 
ATOM 1623 O O   . LEU B 1 60  ? -41.842 5.379   146.144 1.00 14.39  ? 60  LEU B O   1 
ATOM 1624 C CB  . LEU B 1 60  ? -41.908 5.630   142.780 1.00 14.39  ? 60  LEU B CB  1 
ATOM 1625 C CG  . LEU B 1 60  ? -41.707 6.562   141.585 1.00 14.39  ? 60  LEU B CG  1 
ATOM 1626 C CD1 . LEU B 1 60  ? -42.270 5.950   140.312 1.00 14.39  ? 60  LEU B CD1 1 
ATOM 1627 C CD2 . LEU B 1 60  ? -42.328 7.924   141.840 1.00 14.39  ? 60  LEU B CD2 1 
ATOM 1628 N N   . CYS B 1 61  ? -40.840 3.654   145.024 1.00 16.29  ? 61  CYS B N   1 
ATOM 1629 C CA  . CYS B 1 61  ? -41.070 2.630   146.080 1.00 16.29  ? 61  CYS B CA  1 
ATOM 1630 C C   . CYS B 1 61  ? -40.393 3.073   147.379 1.00 16.29  ? 61  CYS B C   1 
ATOM 1631 O O   . CYS B 1 61  ? -41.055 3.014   148.434 1.00 16.29  ? 61  CYS B O   1 
ATOM 1632 C CB  . CYS B 1 61  ? -40.521 1.275   145.655 1.00 16.29  ? 61  CYS B CB  1 
ATOM 1633 S SG  . CYS B 1 61  ? -40.844 -0.038  146.860 1.00 16.29  ? 61  CYS B SG  1 
ATOM 1634 N N   . TRP B 1 62  ? -39.136 3.521   147.309 1.00 15.86  ? 62  TRP B N   1 
ATOM 1635 C CA  . TRP B 1 62  ? -38.363 3.949   148.502 1.00 15.86  ? 62  TRP B CA  1 
ATOM 1636 C C   . TRP B 1 62  ? -39.052 5.170   149.099 1.00 15.86  ? 62  TRP B C   1 
ATOM 1637 O O   . TRP B 1 62  ? -39.101 5.263   150.332 1.00 15.86  ? 62  TRP B O   1 
ATOM 1638 C CB  . TRP B 1 62  ? -36.903 4.236   148.140 1.00 15.86  ? 62  TRP B CB  1 
ATOM 1639 C CG  . TRP B 1 62  ? -36.066 4.602   149.324 1.00 15.86  ? 62  TRP B CG  1 
ATOM 1640 C CD1 . TRP B 1 62  ? -35.486 5.809   149.585 1.00 15.86  ? 62  TRP B CD1 1 
ATOM 1641 C CD2 . TRP B 1 62  ? -35.736 3.751   150.435 1.00 15.86  ? 62  TRP B CD2 1 
ATOM 1642 N NE1 . TRP B 1 62  ? -34.811 5.764   150.773 1.00 15.86  ? 62  TRP B NE1 1 
ATOM 1643 C CE2 . TRP B 1 62  ? -34.943 4.514   151.317 1.00 15.86  ? 62  TRP B CE2 1 
ATOM 1644 C CE3 . TRP B 1 62  ? -36.025 2.422   150.767 1.00 15.86  ? 62  TRP B CE3 1 
ATOM 1645 C CZ2 . TRP B 1 62  ? -34.439 3.990   152.506 1.00 15.86  ? 62  TRP B CZ2 1 
ATOM 1646 C CZ3 . TRP B 1 62  ? -35.528 1.905   151.941 1.00 15.86  ? 62  TRP B CZ3 1 
ATOM 1647 C CH2 . TRP B 1 62  ? -34.745 2.680   152.798 1.00 15.86  ? 62  TRP B CH2 1 
ATOM 1648 N N   . GLY B 1 63  ? -39.566 6.065   148.256 1.00 16.46  ? 63  GLY B N   1 
ATOM 1649 C CA  . GLY B 1 63  ? -40.307 7.252   148.716 1.00 16.46  ? 63  GLY B CA  1 
ATOM 1650 C C   . GLY B 1 63  ? -41.515 6.820   149.516 1.00 16.46  ? 63  GLY B C   1 
ATOM 1651 O O   . GLY B 1 63  ? -41.667 7.323   150.633 1.00 16.46  ? 63  GLY B O   1 
ATOM 1652 N N   . GLU B 1 64  ? -42.309 5.880   148.995 1.00 18.12  ? 64  GLU B N   1 
ATOM 1653 C CA  . GLU B 1 64  ? -43.508 5.355   149.706 1.00 18.12  ? 64  GLU B CA  1 
ATOM 1654 C C   . GLU B 1 64  ? -43.070 4.722   151.031 1.00 18.12  ? 64  GLU B C   1 
ATOM 1655 O O   . GLU B 1 64  ? -43.791 4.901   152.043 1.00 18.12  ? 64  GLU B O   1 
ATOM 1656 C CB  . GLU B 1 64  ? -44.238 4.337   148.831 1.00 18.12  ? 64  GLU B CB  1 
ATOM 1657 C CG  . GLU B 1 64  ? -44.876 4.950   147.599 1.00 18.12  ? 64  GLU B CG  1 
ATOM 1658 C CD  . GLU B 1 64  ? -45.953 5.977   147.892 1.00 18.12  ? 64  GLU B CD  1 
ATOM 1659 O OE1 . GLU B 1 64  ? -46.592 5.877   148.959 1.00 18.12  ? 64  GLU B OE1 1 
ATOM 1660 O OE2 . GLU B 1 64  ? -46.142 6.884   147.060 1.00 18.12  ? 64  GLU B OE2 1 
ATOM 1661 N N   . LEU B 1 65  ? -41.941 4.008   151.035 1.00 19.53  ? 65  LEU B N   1 
ATOM 1662 C CA  . LEU B 1 65  ? -41.417 3.352   152.261 1.00 19.53  ? 65  LEU B CA  1 
ATOM 1663 C C   . LEU B 1 65  ? -41.114 4.426   153.307 1.00 19.53  ? 65  LEU B C   1 
ATOM 1664 O O   . LEU B 1 65  ? -41.565 4.262   154.458 1.00 19.53  ? 65  LEU B O   1 
ATOM 1665 C CB  . LEU B 1 65  ? -40.156 2.558   151.911 1.00 19.53  ? 65  LEU B CB  1 
ATOM 1666 C CG  . LEU B 1 65  ? -40.384 1.288   151.094 1.00 19.53  ? 65  LEU B CG  1 
ATOM 1667 C CD1 . LEU B 1 65  ? -39.078 0.536   150.903 1.00 19.53  ? 65  LEU B CD1 1 
ATOM 1668 C CD2 . LEU B 1 65  ? -41.431 0.400   151.746 1.00 19.53  ? 65  LEU B CD2 1 
ATOM 1669 N N   . MET B 1 66  ? -40.405 5.489   152.922 1.00 20.35  ? 66  MET B N   1 
ATOM 1670 C CA  . MET B 1 66  ? -40.019 6.576   153.859 1.00 20.35  ? 66  MET B CA  1 
ATOM 1671 C C   . MET B 1 66  ? -41.302 7.263   154.322 1.00 20.35  ? 66  MET B C   1 
ATOM 1672 O O   . MET B 1 66  ? -41.336 7.710   155.477 1.00 20.35  ? 66  MET B O   1 
ATOM 1673 C CB  . MET B 1 66  ? -39.092 7.595   153.188 1.00 20.35  ? 66  MET B CB  1 
ATOM 1674 C CG  . MET B 1 66  ? -37.780 7.006   152.694 1.00 20.35  ? 66  MET B CG  1 
ATOM 1675 S SD  . MET B 1 66  ? -36.964 5.914   153.889 1.00 20.35  ? 66  MET B SD  1 
ATOM 1676 C CE  . MET B 1 66  ? -37.644 4.326   153.412 1.00 20.35  ? 66  MET B CE  1 
ATOM 1677 N N   . THR B 1 67  ? -42.318 7.333   153.461 1.00 21.80  ? 67  THR B N   1 
ATOM 1678 C CA  . THR B 1 67  ? -43.629 7.942   153.792 1.00 21.80  ? 67  THR B CA  1 
ATOM 1679 C C   . THR B 1 67  ? -44.247 7.136   154.931 1.00 21.80  ? 67  THR B C   1 
ATOM 1680 O O   . THR B 1 67  ? -44.599 7.752   155.948 1.00 21.80  ? 67  THR B O   1 
ATOM 1681 C CB  . THR B 1 67  ? -44.559 7.976   152.573 1.00 21.80  ? 67  THR B CB  1 
ATOM 1682 O OG1 . THR B 1 67  ? -43.951 8.781   151.560 1.00 21.80  ? 67  THR B OG1 1 
ATOM 1683 C CG2 . THR B 1 67  ? -45.933 8.512   152.905 1.00 21.80  ? 67  THR B CG2 1 
ATOM 1684 N N   . LEU B 1 68  ? -44.329 5.811   154.779 1.00 24.38  ? 68  LEU B N   1 
ATOM 1685 C CA  . LEU B 1 68  ? -44.896 4.929   155.835 1.00 24.38  ? 68  LEU B CA  1 
ATOM 1686 C C   . LEU B 1 68  ? -44.040 5.068   157.097 1.00 24.38  ? 68  LEU B C   1 
ATOM 1687 O O   . LEU B 1 68  ? -44.619 5.015   158.201 1.00 24.38  ? 68  LEU B O   1 
ATOM 1688 C CB  . LEU B 1 68  ? -44.932 3.480   155.340 1.00 24.38  ? 68  LEU B CB  1 
ATOM 1689 C CG  . LEU B 1 68  ? -45.116 2.420   156.427 1.00 24.38  ? 68  LEU B CG  1 
ATOM 1690 C CD1 . LEU B 1 68  ? -46.358 2.687   157.265 1.00 24.38  ? 68  LEU B CD1 1 
ATOM 1691 C CD2 . LEU B 1 68  ? -45.184 1.030   155.817 1.00 24.38  ? 68  LEU B CD2 1 
ATOM 1692 N N   . ALA B 1 69  ? -42.723 5.246   156.950 1.00 26.30  ? 69  ALA B N   1 
ATOM 1693 C CA  . ALA B 1 69  ? -41.798 5.392   158.097 1.00 26.30  ? 69  ALA B CA  1 
ATOM 1694 C C   . ALA B 1 69  ? -42.190 6.647   158.882 1.00 26.30  ? 69  ALA B C   1 
ATOM 1695 O O   . ALA B 1 69  ? -42.389 6.542   160.106 1.00 26.30  ? 69  ALA B O   1 
ATOM 1696 C CB  . ALA B 1 69  ? -40.374 5.456   157.610 1.00 26.30  ? 69  ALA B CB  1 
ATOM 1697 N N   . THR B 1 70  ? -42.343 7.784   158.201 1.00 28.06  ? 70  THR B N   1 
ATOM 1698 C CA  . THR B 1 70  ? -42.743 9.060   158.845 1.00 28.06  ? 70  THR B CA  1 
ATOM 1699 C C   . THR B 1 70  ? -44.102 8.830   159.493 1.00 28.06  ? 70  THR B C   1 
ATOM 1700 O O   . THR B 1 70  ? -44.294 9.281   160.639 1.00 28.06  ? 70  THR B O   1 
ATOM 1701 C CB  . THR B 1 70  ? -42.794 10.208  157.831 1.00 28.06  ? 70  THR B CB  1 
ATOM 1702 O OG1 . THR B 1 70  ? -41.495 10.361  157.260 1.00 28.06  ? 70  THR B OG1 1 
ATOM 1703 C CG2 . THR B 1 70  ? -43.241 11.513  158.452 1.00 28.06  ? 70  THR B CG2 1 
ATOM 1704 N N   . TRP B 1 71  ? -45.029 8.215   158.777 1.00 29.57  ? 71  TRP B N   1 
ATOM 1705 C CA  . TRP B 1 71  ? -46.354 7.914   159.357 1.00 29.57  ? 71  TRP B CA  1 
ATOM 1706 C C   . TRP B 1 71  ? -46.117 7.234   160.702 1.00 29.57  ? 71  TRP B C   1 
ATOM 1707 O O   . TRP B 1 71  ? -46.478 7.838   161.630 1.00 29.57  ? 71  TRP B O   1 
ATOM 1708 C CB  . TRP B 1 71  ? -47.220 7.082   158.416 1.00 29.57  ? 71  TRP B CB  1 
ATOM 1709 C CG  . TRP B 1 71  ? -48.560 6.718   158.974 1.00 29.57  ? 71  TRP B CG  1 
ATOM 1710 C CD1 . TRP B 1 71  ? -49.716 7.434   158.876 1.00 29.57  ? 71  TRP B CD1 1 
ATOM 1711 C CD2 . TRP B 1 71  ? -48.892 5.521   159.697 1.00 29.57  ? 71  TRP B CD2 1 
ATOM 1712 N NE1 . TRP B 1 71  ? -50.742 6.766   159.490 1.00 29.57  ? 71  TRP B NE1 1 
ATOM 1713 C CE2 . TRP B 1 71  ? -50.265 5.592   160.005 1.00 29.57  ? 71  TRP B CE2 1 
ATOM 1714 C CE3 . TRP B 1 71  ? -48.165 4.402   160.111 1.00 29.57  ? 71  TRP B CE3 1 
ATOM 1715 C CZ2 . TRP B 1 71  ? -50.920 4.587   160.710 1.00 29.57  ? 71  TRP B CZ2 1 
ATOM 1716 C CZ3 . TRP B 1 71  ? -48.814 3.408   160.808 1.00 29.57  ? 71  TRP B CZ3 1 
ATOM 1717 C CH2 . TRP B 1 71  ? -50.173 3.501   161.102 1.00 29.57  ? 71  TRP B CH2 1 
ATOM 1718 N N   . VAL B 1 72  ? -45.466 6.071   160.791 1.00 31.49  ? 72  VAL B N   1 
ATOM 1719 C CA  . VAL B 1 72  ? -45.314 5.333   162.085 1.00 31.49  ? 72  VAL B CA  1 
ATOM 1720 C C   . VAL B 1 72  ? -44.673 6.290   163.095 1.00 31.49  ? 72  VAL B C   1 
ATOM 1721 O O   . VAL B 1 72  ? -45.214 6.419   164.194 1.00 31.49  ? 72  VAL B O   1 
ATOM 1722 C CB  . VAL B 1 72  ? -44.509 4.018   161.976 1.00 31.49  ? 72  VAL B CB  1 
ATOM 1723 C CG1 . VAL B 1 72  ? -45.204 2.996   161.097 1.00 31.49  ? 72  VAL B CG1 1 
ATOM 1724 C CG2 . VAL B 1 72  ? -43.077 4.223   161.518 1.00 31.49  ? 72  VAL B CG2 1 
ATOM 1725 N N   . GLY B 1 73  ? -43.598 6.982   162.724 1.00 33.80  ? 73  GLY B N   1 
ATOM 1726 C CA  . GLY B 1 73  ? -42.888 7.892   163.642 1.00 33.80  ? 73  GLY B CA  1 
ATOM 1727 C C   . GLY B 1 73  ? -43.820 8.931   164.240 1.00 33.80  ? 73  GLY B C   1 
ATOM 1728 O O   . GLY B 1 73  ? -43.565 9.343   165.400 1.00 33.80  ? 73  GLY B O   1 
ATOM 1729 N N   . VAL B 1 74  ? -44.894 9.292   163.529 1.00 35.49  ? 74  VAL B N   1 
ATOM 1730 C CA  . VAL B 1 74  ? -45.862 10.336  163.975 1.00 35.49  ? 74  VAL B CA  1 
ATOM 1731 C C   . VAL B 1 74  ? -47.179 9.681   164.409 1.00 35.49  ? 74  VAL B C   1 
ATOM 1732 O O   . VAL B 1 74  ? -47.917 10.331  165.176 1.00 35.49  ? 74  VAL B O   1 
ATOM 1733 C CB  . VAL B 1 74  ? -46.093 11.360  162.847 1.00 30.00  ? 74  VAL B CB  1 
ATOM 1734 C CG1 . VAL B 1 74  ? -47.106 12.423  163.240 1.00 30.00  ? 74  VAL B CG1 1 
ATOM 1735 C CG2 . VAL B 1 74  ? -44.788 12.003  162.404 1.00 30.00  ? 74  VAL B CG2 1 
ATOM 1736 N N   . ASN B 1 75  ? -47.465 8.454   163.963 1.00 35.38  ? 75  ASN B N   1 
ATOM 1737 C CA  . ASN B 1 75  ? -48.748 7.760   164.270 1.00 35.38  ? 75  ASN B CA  1 
ATOM 1738 C C   . ASN B 1 75  ? -48.550 6.806   165.449 1.00 35.38  ? 75  ASN B C   1 
ATOM 1739 O O   . ASN B 1 75  ? -49.171 7.047   166.501 1.00 35.38  ? 75  ASN B O   1 
ATOM 1740 C CB  . ASN B 1 75  ? -49.328 7.007   163.072 1.00 35.38  ? 75  ASN B CB  1 
ATOM 1741 C CG  . ASN B 1 75  ? -49.977 7.934   162.069 1.00 35.38  ? 75  ASN B CG  1 
ATOM 1742 O OD1 . ASN B 1 75  ? -51.181 7.865   161.838 1.00 35.38  ? 75  ASN B OD1 1 
ATOM 1743 N ND2 . ASN B 1 75  ? -49.189 8.814   161.475 1.00 35.38  ? 75  ASN B ND2 1 
ATOM 1744 N N   . LEU B 1 76  ? -47.727 5.766   165.290 1.00 37.33  ? 76  LEU B N   1 
ATOM 1745 C CA  . LEU B 1 76  ? -47.433 4.817   166.395 1.00 37.33  ? 76  LEU B CA  1 
ATOM 1746 C C   . LEU B 1 76  ? -47.074 5.653   167.623 1.00 37.33  ? 76  LEU B C   1 
ATOM 1747 O O   . LEU B 1 76  ? -46.181 6.508   167.493 1.00 37.33  ? 76  LEU B O   1 
ATOM 1748 C CB  . LEU B 1 76  ? -46.290 3.879   165.993 1.00 37.33  ? 76  LEU B CB  1 
ATOM 1749 C CG  . LEU B 1 76  ? -46.581 2.932   164.831 1.00 37.33  ? 76  LEU B CG  1 
ATOM 1750 C CD1 . LEU B 1 76  ? -45.329 2.165   164.437 1.00 37.33  ? 76  LEU B CD1 1 
ATOM 1751 C CD2 . LEU B 1 76  ? -47.710 1.970   165.168 1.00 37.33  ? 76  LEU B CD2 1 
ATOM 1752 N N   . GLU B 1 77  ? -47.746 5.436   168.759 1.00 42.41  ? 77  GLU B N   1 
ATOM 1753 C CA  . GLU B 1 77  ? -47.529 6.240   169.992 1.00 42.41  ? 77  GLU B CA  1 
ATOM 1754 C C   . GLU B 1 77  ? -46.625 5.468   170.953 1.00 42.41  ? 77  GLU B C   1 
ATOM 1755 O O   . GLU B 1 77  ? -46.487 5.916   172.108 1.00 42.41  ? 77  GLU B O   1 
ATOM 1756 C CB  . GLU B 1 77  ? -48.874 6.578   170.640 1.00 42.41  ? 77  GLU B CB  1 
ATOM 1757 C CG  . GLU B 1 77  ? -49.879 7.182   169.676 1.00 42.41  ? 77  GLU B CG  1 
ATOM 1758 C CD  . GLU B 1 77  ? -49.489 8.530   169.095 1.00 42.41  ? 77  GLU B CD  1 
ATOM 1759 O OE1 . GLU B 1 77  ? -48.424 9.055   169.475 1.00 42.41  ? 77  GLU B OE1 1 
ATOM 1760 O OE2 . GLU B 1 77  ? -50.254 9.054   168.261 1.00 42.41  ? 77  GLU B OE2 1 
ATOM 1761 N N   . ASP B 1 78  ? -46.031 4.360   170.503 1.00 42.07  ? 78  ASP B N   1 
ATOM 1762 C CA  . ASP B 1 78  ? -45.105 3.542   171.329 1.00 42.07  ? 78  ASP B CA  1 
ATOM 1763 C C   . ASP B 1 78  ? -43.675 3.915   170.936 1.00 42.07  ? 78  ASP B C   1 
ATOM 1764 O O   . ASP B 1 78  ? -43.396 3.919   169.735 1.00 42.07  ? 78  ASP B O   1 
ATOM 1765 C CB  . ASP B 1 78  ? -45.392 2.051   171.144 1.00 42.07  ? 78  ASP B CB  1 
ATOM 1766 C CG  . ASP B 1 78  ? -44.502 1.127   171.958 1.00 42.07  ? 78  ASP B CG  1 
ATOM 1767 O OD1 . ASP B 1 78  ? -43.584 1.634   172.630 1.00 42.07  ? 78  ASP B OD1 1 
ATOM 1768 O OD2 . ASP B 1 78  ? -44.732 -0.097  171.910 1.00 42.07  ? 78  ASP B OD2 1 
ATOM 1769 N N   . PRO B 1 79  ? -42.774 4.284   171.871 1.00 41.62  ? 79  PRO B N   1 
ATOM 1770 C CA  . PRO B 1 79  ? -41.375 4.550   171.521 1.00 41.62  ? 79  PRO B CA  1 
ATOM 1771 C C   . PRO B 1 79  ? -40.640 3.269   171.103 1.00 41.62  ? 79  PRO B C   1 
ATOM 1772 O O   . PRO B 1 79  ? -39.828 3.351   170.203 1.00 41.62  ? 79  PRO B O   1 
ATOM 1773 C CB  . PRO B 1 79  ? -40.780 5.127   172.813 1.00 41.62  ? 79  PRO B CB  1 
ATOM 1774 C CG  . PRO B 1 79  ? -41.656 4.554   173.903 1.00 41.62  ? 79  PRO B CG  1 
ATOM 1775 C CD  . PRO B 1 79  ? -43.041 4.502   173.293 1.00 41.62  ? 79  PRO B CD  1 
ATOM 1776 N N   . ALA B 1 80  ? -40.936 2.134   171.739 1.00 40.17  ? 80  ALA B N   1 
ATOM 1777 C CA  . ALA B 1 80  ? -40.283 0.838   171.442 1.00 40.17  ? 80  ALA B CA  1 
ATOM 1778 C C   . ALA B 1 80  ? -40.696 0.360   170.048 1.00 40.17  ? 80  ALA B C   1 
ATOM 1779 O O   . ALA B 1 80  ? -39.792 0.065   169.249 1.00 40.17  ? 80  ALA B O   1 
ATOM 1780 C CB  . ALA B 1 80  ? -40.652 -0.170  172.498 1.00 40.17  ? 80  ALA B CB  1 
ATOM 1781 N N   . SER B 1 81  ? -41.999 0.284   169.765 1.00 39.28  ? 81  SER B N   1 
ATOM 1782 C CA  . SER B 1 81  ? -42.529 -0.186  168.465 1.00 39.28  ? 81  SER B CA  1 
ATOM 1783 C C   . SER B 1 81  ? -42.103 0.789   167.371 1.00 39.28  ? 81  SER B C   1 
ATOM 1784 O O   . SER B 1 81  ? -41.578 0.326   166.348 1.00 39.28  ? 81  SER B O   1 
ATOM 1785 C CB  . SER B 1 81  ? -44.015 -0.337  168.520 1.00 39.28  ? 81  SER B CB  1 
ATOM 1786 O OG  . SER B 1 81  ? -44.383 -1.376  169.413 1.00 39.28  ? 81  SER B OG  1 
ATOM 1787 N N   . ARG B 1 82  ? -42.290 2.086   167.592 1.00 39.05  ? 82  ARG B N   1 
ATOM 1788 C CA  . ARG B 1 82  ? -41.898 3.107   166.596 1.00 39.05  ? 82  ARG B CA  1 
ATOM 1789 C C   . ARG B 1 82  ? -40.507 2.754   166.089 1.00 39.05  ? 82  ARG B C   1 
ATOM 1790 O O   . ARG B 1 82  ? -40.340 2.636   164.867 1.00 39.05  ? 82  ARG B O   1 
ATOM 1791 C CB  . ARG B 1 82  ? -41.874 4.506   167.211 1.00 39.05  ? 82  ARG B CB  1 
ATOM 1792 C CG  . ARG B 1 82  ? -43.170 5.282   167.041 1.00 39.05  ? 82  ARG B CG  1 
ATOM 1793 C CD  . ARG B 1 82  ? -42.951 6.768   167.231 1.00 39.05  ? 82  ARG B CD  1 
ATOM 1794 N NE  . ARG B 1 82  ? -42.206 7.070   168.442 1.00 39.05  ? 82  ARG B NE  1 
ATOM 1795 C CZ  . ARG B 1 82  ? -42.730 7.141   169.659 1.00 39.05  ? 82  ARG B CZ  1 
ATOM 1796 N NH1 . ARG B 1 82  ? -44.016 6.913   169.850 1.00 39.05  ? 82  ARG B NH1 1 
ATOM 1797 N NH2 . ARG B 1 82  ? -41.960 7.430   170.692 1.00 39.05  ? 82  ARG B NH2 1 
ATOM 1798 N N   . ASP B 1 83  ? -39.560 2.535   166.994 1.00 37.45  ? 83  ASP B N   1 
ATOM 1799 C CA  . ASP B 1 83  ? -38.151 2.277   166.614 1.00 37.45  ? 83  ASP B CA  1 
ATOM 1800 C C   . ASP B 1 83  ? -38.054 0.989   165.808 1.00 37.45  ? 83  ASP B C   1 
ATOM 1801 O O   . ASP B 1 83  ? -37.452 1.024   164.728 1.00 37.45  ? 83  ASP B O   1 
ATOM 1802 C CB  . ASP B 1 83  ? -37.274 2.205   167.858 1.00 37.45  ? 83  ASP B CB  1 
ATOM 1803 C CG  . ASP B 1 83  ? -37.326 3.465   168.704 1.00 37.45  ? 83  ASP B CG  1 
ATOM 1804 O OD1 . ASP B 1 83  ? -38.044 4.404   168.307 1.00 37.45  ? 83  ASP B OD1 1 
ATOM 1805 O OD2 . ASP B 1 83  ? -36.653 3.495   169.751 1.00 37.45  ? 83  ASP B OD2 1 
ATOM 1806 N N   . LEU B 1 84  ? -38.629 -0.099  166.301 1.00 35.30  ? 84  LEU B N   1 
ATOM 1807 C CA  . LEU B 1 84  ? -38.524 -1.412  165.626 1.00 35.30  ? 84  LEU B CA  1 
ATOM 1808 C C   . LEU B 1 84  ? -38.908 -1.251  164.158 1.00 35.30  ? 84  LEU B C   1 
ATOM 1809 O O   . LEU B 1 84  ? -38.147 -1.717  163.301 1.00 35.30  ? 84  LEU B O   1 
ATOM 1810 C CB  . LEU B 1 84  ? -39.463 -2.396  166.318 1.00 35.30  ? 84  LEU B CB  1 
ATOM 1811 C CG  . LEU B 1 84  ? -39.061 -2.807  167.730 1.00 35.30  ? 84  LEU B CG  1 
ATOM 1812 C CD1 . LEU B 1 84  ? -40.224 -3.470  168.447 1.00 35.30  ? 84  LEU B CD1 1 
ATOM 1813 C CD2 . LEU B 1 84  ? -37.855 -3.728  167.694 1.00 35.30  ? 84  LEU B CD2 1 
ATOM 1814 N N   . VAL B 1 85  ? -40.032 -0.602  163.873 1.00 32.55  ? 85  VAL B N   1 
ATOM 1815 C CA  . VAL B 1 85  ? -40.537 -0.479  162.479 1.00 32.55  ? 85  VAL B CA  1 
ATOM 1816 C C   . VAL B 1 85  ? -39.582 0.402   161.684 1.00 32.55  ? 85  VAL B C   1 
ATOM 1817 O O   . VAL B 1 85  ? -39.119 -0.046  160.626 1.00 32.55  ? 85  VAL B O   1 
ATOM 1818 C CB  . VAL B 1 85  ? -41.964 0.087   162.453 1.00 32.55  ? 85  VAL B CB  1 
ATOM 1819 C CG1 . VAL B 1 85  ? -42.449 0.316   161.033 1.00 32.55  ? 85  VAL B CG1 1 
ATOM 1820 C CG2 . VAL B 1 85  ? -42.937 -0.795  163.218 1.00 32.55  ? 85  VAL B CG2 1 
ATOM 1821 N N   . VAL B 1 86  ? -39.264 1.588   162.187 1.00 30.14  ? 86  VAL B N   1 
ATOM 1822 C CA  . VAL B 1 86  ? -38.414 2.554   161.439 1.00 30.14  ? 86  VAL B CA  1 
ATOM 1823 C C   . VAL B 1 86  ? -37.093 1.870   161.108 1.00 30.14  ? 86  VAL B C   1 
ATOM 1824 O O   . VAL B 1 86  ? -36.618 2.039   159.976 1.00 30.14  ? 86  VAL B O   1 
ATOM 1825 C CB  . VAL B 1 86  ? -38.202 3.845   162.243 1.00 30.14  ? 86  VAL B CB  1 
ATOM 1826 C CG1 . VAL B 1 86  ? -37.157 4.737   161.602 1.00 30.14  ? 86  VAL B CG1 1 
ATOM 1827 C CG2 . VAL B 1 86  ? -39.510 4.594   162.431 1.00 30.14  ? 86  VAL B CG2 1 
ATOM 1828 N N   . SER B 1 87  ? -36.542 1.093   162.034 1.00 30.45  ? 87  SER B N   1 
ATOM 1829 C CA  . SER B 1 87  ? -35.236 0.420   161.841 1.00 30.45  ? 87  SER B CA  1 
ATOM 1830 C C   . SER B 1 87  ? -35.355 -0.629  160.744 1.00 30.45  ? 87  SER B C   1 
ATOM 1831 O O   . SER B 1 87  ? -34.482 -0.655  159.871 1.00 30.45  ? 87  SER B O   1 
ATOM 1832 C CB  . SER B 1 87  ? -34.751 -0.190  163.115 1.00 30.00  ? 87  SER B CB  1 
ATOM 1833 O OG  . SER B 1 87  ? -35.580 -1.267  163.519 1.00 30.00  ? 87  SER B OG  1 
ATOM 1834 N N   . TYR B 1 88  ? -36.397 -1.453  160.772 1.00 25.67  ? 88  TYR B N   1 
ATOM 1835 C CA  . TYR B 1 88  ? -36.578 -2.536  159.781 1.00 25.67  ? 88  TYR B CA  1 
ATOM 1836 C C   . TYR B 1 88  ? -36.572 -1.916  158.395 1.00 25.67  ? 88  TYR B C   1 
ATOM 1837 O O   . TYR B 1 88  ? -35.847 -2.410  157.522 1.00 25.67  ? 88  TYR B O   1 
ATOM 1838 C CB  . TYR B 1 88  ? -37.889 -3.277  160.025 1.00 25.67  ? 88  TYR B CB  1 
ATOM 1839 C CG  . TYR B 1 88  ? -38.222 -4.329  159.001 1.00 25.67  ? 88  TYR B CG  1 
ATOM 1840 C CD1 . TYR B 1 88  ? -38.777 -3.986  157.782 1.00 25.67  ? 88  TYR B CD1 1 
ATOM 1841 C CD2 . TYR B 1 88  ? -37.995 -5.668  159.257 1.00 25.67  ? 88  TYR B CD2 1 
ATOM 1842 C CE1 . TYR B 1 88  ? -39.093 -4.948  156.838 1.00 25.67  ? 88  TYR B CE1 1 
ATOM 1843 C CE2 . TYR B 1 88  ? -38.304 -6.643  158.326 1.00 25.67  ? 88  TYR B CE2 1 
ATOM 1844 C CZ  . TYR B 1 88  ? -38.858 -6.281  157.112 1.00 25.67  ? 88  TYR B CZ  1 
ATOM 1845 O OH  . TYR B 1 88  ? -39.165 -7.235  156.188 1.00 25.67  ? 88  TYR B OH  1 
ATOM 1846 N N   . VAL B 1 89  ? -37.266 -0.793  158.212 1.00 24.30  ? 89  VAL B N   1 
ATOM 1847 C CA  . VAL B 1 89  ? -37.448 -0.158  156.875 1.00 24.30  ? 89  VAL B CA  1 
ATOM 1848 C C   . VAL B 1 89  ? -36.136 0.445   156.361 1.00 24.30  ? 89  VAL B C   1 
ATOM 1849 O O   . VAL B 1 89  ? -35.896 0.345   155.171 1.00 24.30  ? 89  VAL B O   1 
ATOM 1850 C CB  . VAL B 1 89  ? -38.603 0.855   156.959 1.00 24.30  ? 89  VAL B CB  1 
ATOM 1851 C CG1 . VAL B 1 89  ? -38.712 1.706   155.703 1.00 24.30  ? 89  VAL B CG1 1 
ATOM 1852 C CG2 . VAL B 1 89  ? -39.918 0.158   157.254 1.00 24.30  ? 89  VAL B CG2 1 
ATOM 1853 N N   . ASN B 1 90  ? -35.293 1.003   157.217 1.00 24.99  ? 90  ASN B N   1 
ATOM 1854 C CA  . ASN B 1 90  ? -34.033 1.676   156.795 1.00 24.99  ? 90  ASN B CA  1 
ATOM 1855 C C   . ASN B 1 90  ? -32.952 0.613   156.670 1.00 24.99  ? 90  ASN B C   1 
ATOM 1856 O O   . ASN B 1 90  ? -32.053 0.796   155.859 1.00 24.99  ? 90  ASN B O   1 
ATOM 1857 C CB  . ASN B 1 90  ? -33.687 2.843   157.717 1.00 24.99  ? 90  ASN B CB  1 
ATOM 1858 C CG  . ASN B 1 90  ? -34.660 3.990   157.548 1.00 24.99  ? 90  ASN B CG  1 
ATOM 1859 O OD1 . ASN B 1 90  ? -34.311 5.033   157.005 1.00 24.99  ? 90  ASN B OD1 1 
ATOM 1860 N ND2 . ASN B 1 90  ? -35.895 3.792   157.980 1.00 24.99  ? 90  ASN B ND2 1 
ATOM 1861 N N   . THR B 1 91  ? -33.075 -0.491  157.381 1.00 23.87  ? 91  THR B N   1 
ATOM 1862 C CA  . THR B 1 91  ? -32.030 -1.533  157.354 1.00 23.87  ? 91  THR B CA  1 
ATOM 1863 C C   . THR B 1 91  ? -32.387 -2.577  156.299 1.00 23.87  ? 91  THR B C   1 
ATOM 1864 O O   . THR B 1 91  ? -31.769 -2.538  155.256 1.00 23.87  ? 91  THR B O   1 
ATOM 1865 C CB  . THR B 1 91  ? -31.787 -2.110  158.753 1.00 23.87  ? 91  THR B CB  1 
ATOM 1866 O OG1 . THR B 1 91  ? -30.548 -2.815  158.698 1.00 23.87  ? 91  THR B OG1 1 
ATOM 1867 C CG2 . THR B 1 91  ? -32.881 -3.034  159.241 1.00 23.87  ? 91  THR B CG2 1 
ATOM 1868 N N   . ASN B 1 92  ? -33.414 -3.383  156.498 1.00 22.34  ? 92  ASN B N   1 
ATOM 1869 C CA  . ASN B 1 92  ? -33.723 -4.516  155.597 1.00 22.34  ? 92  ASN B CA  1 
ATOM 1870 C C   . ASN B 1 92  ? -34.123 -4.010  154.213 1.00 22.34  ? 92  ASN B C   1 
ATOM 1871 O O   . ASN B 1 92  ? -33.403 -4.316  153.229 1.00 22.34  ? 92  ASN B O   1 
ATOM 1872 C CB  . ASN B 1 92  ? -34.768 -5.412  156.249 1.00 22.34  ? 92  ASN B CB  1 
ATOM 1873 C CG  . ASN B 1 92  ? -34.206 -6.183  157.419 1.00 22.34  ? 92  ASN B CG  1 
ATOM 1874 O OD1 . ASN B 1 92  ? -33.000 -6.394  157.505 1.00 22.34  ? 92  ASN B OD1 1 
ATOM 1875 N ND2 . ASN B 1 92  ? -35.067 -6.579  158.337 1.00 22.34  ? 92  ASN B ND2 1 
ATOM 1876 N N   . MET B 1 93  ? -35.195 -3.232  154.126 1.00 20.11  ? 93  MET B N   1 
ATOM 1877 C CA  . MET B 1 93  ? -35.702 -2.765  152.821 1.00 20.11  ? 93  MET B CA  1 
ATOM 1878 C C   . MET B 1 93  ? -34.688 -1.766  152.292 1.00 20.11  ? 93  MET B C   1 
ATOM 1879 O O   . MET B 1 93  ? -34.683 -1.553  151.083 1.00 20.11  ? 93  MET B O   1 
ATOM 1880 C CB  . MET B 1 93  ? -37.090 -2.137  152.953 1.00 20.11  ? 93  MET B CB  1 
ATOM 1881 C CG  . MET B 1 93  ? -38.123 -3.098  153.510 1.00 20.11  ? 93  MET B CG  1 
ATOM 1882 S SD  . MET B 1 93  ? -39.764 -2.360  153.706 1.00 20.11  ? 93  MET B SD  1 
ATOM 1883 C CE  . MET B 1 93  ? -40.643 -3.083  152.323 1.00 20.11  ? 93  MET B CE  1 
ATOM 1884 N N   . GLY B 1 94  ? -33.830 -1.236  153.169 1.00 16.16  ? 94  GLY B N   1 
ATOM 1885 C CA  . GLY B 1 94  ? -32.812 -0.250  152.782 1.00 16.16  ? 94  GLY B CA  1 
ATOM 1886 C C   . GLY B 1 94  ? -31.715 -0.914  151.993 1.00 16.16  ? 94  GLY B C   1 
ATOM 1887 O O   . GLY B 1 94  ? -31.346 -0.355  150.967 1.00 16.16  ? 94  GLY B O   1 
ATOM 1888 N N   . LEU B 1 95  ? -31.261 -2.088  152.429 1.00 14.37  ? 95  LEU B N   1 
ATOM 1889 C CA  . LEU B 1 95  ? -30.138 -2.809  151.786 1.00 14.37  ? 95  LEU B CA  1 
ATOM 1890 C C   . LEU B 1 95  ? -30.624 -3.345  150.461 1.00 14.37  ? 95  LEU B C   1 
ATOM 1891 O O   . LEU B 1 95  ? -29.816 -3.478  149.562 1.00 14.37  ? 95  LEU B O   1 
ATOM 1892 C CB  . LEU B 1 95  ? -29.691 -3.957  152.683 1.00 14.37  ? 95  LEU B CB  1 
ATOM 1893 C CG  . LEU B 1 95  ? -28.681 -4.922  152.065 1.00 14.37  ? 95  LEU B CG  1 
ATOM 1894 C CD1 . LEU B 1 95  ? -27.393 -4.205  151.688 1.00 14.37  ? 95  LEU B CD1 1 
ATOM 1895 C CD2 . LEU B 1 95  ? -28.396 -6.071  153.017 1.00 14.37  ? 95  LEU B CD2 1 
ATOM 1896 N N   . LYS B 1 96  ? -31.897 -3.675  150.376 1.00 14.50  ? 96  LYS B N   1 
ATOM 1897 C CA  . LYS B 1 96  ? -32.478 -4.275  149.142 1.00 14.50  ? 96  LYS B CA  1 
ATOM 1898 C C   . LYS B 1 96  ? -32.497 -3.168  148.091 1.00 14.50  ? 96  LYS B C   1 
ATOM 1899 O O   . LYS B 1 96  ? -32.204 -3.463  146.925 1.00 14.50  ? 96  LYS B O   1 
ATOM 1900 C CB  . LYS B 1 96  ? -33.887 -4.808  149.408 1.00 14.50  ? 96  LYS B CB  1 
ATOM 1901 C CG  . LYS B 1 96  ? -33.976 -5.976  150.378 1.00 14.50  ? 96  LYS B CG  1 
ATOM 1902 C CD  . LYS B 1 96  ? -35.349 -6.125  150.995 1.00 14.50  ? 96  LYS B CD  1 
ATOM 1903 C CE  . LYS B 1 96  ? -35.542 -7.443  151.714 1.00 14.50  ? 96  LYS B CE  1 
ATOM 1904 N NZ  . LYS B 1 96  ? -35.588 -8.577  150.763 1.00 14.50  ? 96  LYS B NZ  1 
ATOM 1905 N N   . PHE B 1 97  ? -32.834 -1.946  148.494 1.00 13.20  ? 97  PHE B N   1 
ATOM 1906 C CA  . PHE B 1 97  ? -32.908 -0.735  147.644 1.00 13.20  ? 97  PHE B CA  1 
ATOM 1907 C C   . PHE B 1 97  ? -31.499 -0.374  147.192 1.00 13.20  ? 97  PHE B C   1 
ATOM 1908 O O   . PHE B 1 97  ? -31.317 -0.067  146.012 1.00 13.20  ? 97  PHE B O   1 
ATOM 1909 C CB  . PHE B 1 97  ? -33.549 0.418   148.409 1.00 30.00  ? 97  PHE B CB  1 
ATOM 1910 C CG  . PHE B 1 97  ? -33.723 1.696   147.632 1.00 30.00  ? 97  PHE B CG  1 
ATOM 1911 C CD1 . PHE B 1 97  ? -34.363 1.702   146.405 1.00 30.00  ? 97  PHE B CD1 1 
ATOM 1912 C CD2 . PHE B 1 97  ? -33.274 2.900   148.147 1.00 30.00  ? 97  PHE B CD2 1 
ATOM 1913 C CE1 . PHE B 1 97  ? -34.530 2.881   145.701 1.00 30.00  ? 97  PHE B CE1 1 
ATOM 1914 C CE2 . PHE B 1 97  ? -33.444 4.079   147.440 1.00 30.00  ? 97  PHE B CE2 1 
ATOM 1915 C CZ  . PHE B 1 97  ? -34.073 4.068   146.221 1.00 30.00  ? 97  PHE B CZ  1 
ATOM 1916 N N   . ARG B 1 98  ? -30.531 -0.432  148.095 1.00 12.14  ? 98  ARG B N   1 
ATOM 1917 C CA  . ARG B 1 98  ? -29.139 -0.045  147.777 1.00 12.14  ? 98  ARG B CA  1 
ATOM 1918 C C   . ARG B 1 98  ? -28.619 -0.980  146.691 1.00 12.14  ? 98  ARG B C   1 
ATOM 1919 O O   . ARG B 1 98  ? -27.969 -0.485  145.763 1.00 12.14  ? 98  ARG B O   1 
ATOM 1920 C CB  . ARG B 1 98  ? -28.300 -0.073  149.052 1.00 12.14  ? 98  ARG B CB  1 
ATOM 1921 C CG  . ARG B 1 98  ? -28.652 1.031   150.039 1.00 12.14  ? 98  ARG B CG  1 
ATOM 1922 C CD  . ARG B 1 98  ? -28.130 0.699   151.416 1.00 12.14  ? 98  ARG B CD  1 
ATOM 1923 N NE  . ARG B 1 98  ? -26.703 0.432   151.372 1.00 12.14  ? 98  ARG B NE  1 
ATOM 1924 C CZ  . ARG B 1 98  ? -26.013 -0.146  152.345 1.00 12.14  ? 98  ARG B CZ  1 
ATOM 1925 N NH1 . ARG B 1 98  ? -26.617 -0.539  153.452 1.00 12.14  ? 98  ARG B NH1 1 
ATOM 1926 N NH2 . ARG B 1 98  ? -24.716 -0.342  152.200 1.00 12.14  ? 98  ARG B NH2 1 
ATOM 1927 N N   . GLN B 1 99  ? -28.930 -2.268  146.769 1.00 10.96  ? 99  GLN B N   1 
ATOM 1928 C CA  . GLN B 1 99  ? -28.435 -3.263  145.791 1.00 10.96  ? 99  GLN B CA  1 
ATOM 1929 C C   . GLN B 1 99  ? -28.992 -2.923  144.415 1.00 10.96  ? 99  GLN B C   1 
ATOM 1930 O O   . GLN B 1 99  ? -28.201 -2.882  143.465 1.00 10.96  ? 99  GLN B O   1 
ATOM 1931 C CB  . GLN B 1 99  ? -28.843 -4.674  146.195 1.00 10.96  ? 99  GLN B CB  1 
ATOM 1932 C CG  . GLN B 1 99  ? -28.192 -5.755  145.348 1.00 10.96  ? 99  GLN B CG  1 
ATOM 1933 C CD  . GLN B 1 99  ? -28.373 -7.124  145.954 1.00 10.96  ? 99  GLN B CD  1 
ATOM 1934 O OE1 . GLN B 1 99  ? -29.407 -7.764  145.789 1.00 10.96  ? 99  GLN B OE1 1 
ATOM 1935 N NE2 . GLN B 1 99  ? -27.363 -7.579  146.674 1.00 10.96  ? 99  GLN B NE2 1 
ATOM 1936 N N   . LEU B 1 100 ? -30.288 -2.655  144.309 1.00 11.11  ? 100 LEU B N   1 
ATOM 1937 C CA  . LEU B 1 100 ? -30.936 -2.387  143.003 1.00 11.11  ? 100 LEU B CA  1 
ATOM 1938 C C   . LEU B 1 100 ? -30.429 -1.063  142.442 1.00 11.11  ? 100 LEU B C   1 
ATOM 1939 O O   . LEU B 1 100 ? -30.085 -1.029  141.256 1.00 11.11  ? 100 LEU B O   1 
ATOM 1940 C CB  . LEU B 1 100 ? -32.451 -2.360  143.176 1.00 11.11  ? 100 LEU B CB  1 
ATOM 1941 C CG  . LEU B 1 100 ? -33.236 -2.074  141.902 1.00 11.11  ? 100 LEU B CG  1 
ATOM 1942 C CD1 . LEU B 1 100 ? -34.494 -2.917  141.841 1.00 11.11  ? 100 LEU B CD1 1 
ATOM 1943 C CD2 . LEU B 1 100 ? -33.570 -0.599  141.800 1.00 11.11  ? 100 LEU B CD2 1 
ATOM 1944 N N   . LEU B 1 101 ? -30.377 -0.019  143.258 1.00 12.09  ? 101 LEU B N   1 
ATOM 1945 C CA  . LEU B 1 101 ? -29.925 1.309   142.792 1.00 12.09  ? 101 LEU B CA  1 
ATOM 1946 C C   . LEU B 1 101 ? -28.526 1.155   142.208 1.00 12.09  ? 101 LEU B C   1 
ATOM 1947 O O   . LEU B 1 101 ? -28.296 1.671   141.113 1.00 12.09  ? 101 LEU B O   1 
ATOM 1948 C CB  . LEU B 1 101 ? -29.920 2.302   143.954 1.00 12.09  ? 101 LEU B CB  1 
ATOM 1949 C CG  . LEU B 1 101 ? -31.222 3.054   144.202 1.00 12.09  ? 101 LEU B CG  1 
ATOM 1950 C CD1 . LEU B 1 101 ? -31.005 4.156   145.224 1.00 12.09  ? 101 LEU B CD1 1 
ATOM 1951 C CD2 . LEU B 1 101 ? -31.778 3.634   142.913 1.00 12.09  ? 101 LEU B CD2 1 
ATOM 1952 N N   . TRP B 1 102 ? -27.637 0.445   142.890 1.00 10.08  ? 102 TRP B N   1 
ATOM 1953 C CA  . TRP B 1 102 ? -26.242 0.272   142.427 1.00 10.08  ? 102 TRP B CA  1 
ATOM 1954 C C   . TRP B 1 102 ? -26.253 -0.415  141.070 1.00 10.08  ? 102 TRP B C   1 
ATOM 1955 O O   . TRP B 1 102 ? -25.576 0.081   140.170 1.00 10.08  ? 102 TRP B O   1 
ATOM 1956 C CB  . TRP B 1 102 ? -25.418 -0.520  143.438 1.00 10.08  ? 102 TRP B CB  1 
ATOM 1957 C CG  . TRP B 1 102 ? -24.051 -0.872  142.949 1.00 10.08  ? 102 TRP B CG  1 
ATOM 1958 C CD1 . TRP B 1 102 ? -22.905 -0.157  143.122 1.00 10.08  ? 102 TRP B CD1 1 
ATOM 1959 C CD2 . TRP B 1 102 ? -23.688 -2.034  142.187 1.00 10.08  ? 102 TRP B CD2 1 
ATOM 1960 N NE1 . TRP B 1 102 ? -21.852 -0.794  142.523 1.00 10.08  ? 102 TRP B NE1 1 
ATOM 1961 C CE2 . TRP B 1 102 ? -22.303 -1.947  141.942 1.00 10.08  ? 102 TRP B CE2 1 
ATOM 1962 C CE3 . TRP B 1 102 ? -24.393 -3.133  141.692 1.00 10.08  ? 102 TRP B CE3 1 
ATOM 1963 C CZ2 . TRP B 1 102 ? -21.615 -2.923  141.225 1.00 10.08  ? 102 TRP B CZ2 1 
ATOM 1964 C CZ3 . TRP B 1 102 ? -23.714 -4.095  140.982 1.00 10.08  ? 102 TRP B CZ3 1 
ATOM 1965 C CH2 . TRP B 1 102 ? -22.344 -3.990  140.753 1.00 10.08  ? 102 TRP B CH2 1 
ATOM 1966 N N   . PHE B 1 103 ? -27.009 -1.495  140.912 1.00 10.22  ? 103 PHE B N   1 
ATOM 1967 C CA  . PHE B 1 103 ? -27.020 -2.277  139.656 1.00 10.22  ? 103 PHE B CA  1 
ATOM 1968 C C   . PHE B 1 103 ? -27.416 -1.375  138.500 1.00 10.22  ? 103 PHE B C   1 
ATOM 1969 O O   . PHE B 1 103 ? -26.659 -1.304  137.531 1.00 10.22  ? 103 PHE B O   1 
ATOM 1970 C CB  . PHE B 1 103 ? -27.987 -3.453  139.748 1.00 10.22  ? 103 PHE B CB  1 
ATOM 1971 C CG  . PHE B 1 103 ? -28.109 -4.261  138.485 1.00 10.22  ? 103 PHE B CG  1 
ATOM 1972 C CD1 . PHE B 1 103 ? -27.153 -5.206  138.155 1.00 10.22  ? 103 PHE B CD1 1 
ATOM 1973 C CD2 . PHE B 1 103 ? -29.179 -4.077  137.628 1.00 10.22  ? 103 PHE B CD2 1 
ATOM 1974 C CE1 . PHE B 1 103 ? -27.265 -5.950  136.993 1.00 10.22  ? 103 PHE B CE1 1 
ATOM 1975 C CE2 . PHE B 1 103 ? -29.290 -4.822  136.464 1.00 10.22  ? 103 PHE B CE2 1 
ATOM 1976 C CZ  . PHE B 1 103 ? -28.334 -5.756  136.150 1.00 10.22  ? 103 PHE B CZ  1 
ATOM 1977 N N   . HIS B 1 104 ? -28.543 -0.685  138.597 1.00 11.17  ? 104 HIS B N   1 
ATOM 1978 C CA  . HIS B 1 104 ? -29.068 0.134   137.478 1.00 11.17  ? 104 HIS B CA  1 
ATOM 1979 C C   . HIS B 1 104 ? -28.152 1.326   137.237 1.00 11.17  ? 104 HIS B C   1 
ATOM 1980 O O   . HIS B 1 104 ? -27.788 1.550   136.083 1.00 11.17  ? 104 HIS B O   1 
ATOM 1981 C CB  . HIS B 1 104 ? -30.508 0.542   137.759 1.00 11.17  ? 104 HIS B CB  1 
ATOM 1982 C CG  . HIS B 1 104 ? -31.445 -0.610  137.763 1.00 11.17  ? 104 HIS B CG  1 
ATOM 1983 N ND1 . HIS B 1 104 ? -31.637 -1.399  136.651 1.00 11.17  ? 104 HIS B ND1 1 
ATOM 1984 C CD2 . HIS B 1 104 ? -32.232 -1.118  138.730 1.00 11.17  ? 104 HIS B CD2 1 
ATOM 1985 C CE1 . HIS B 1 104 ? -32.505 -2.341  136.934 1.00 11.17  ? 104 HIS B CE1 1 
ATOM 1986 N NE2 . HIS B 1 104 ? -32.885 -2.193  138.202 1.00 11.17  ? 104 HIS B NE2 1 
ATOM 1987 N N   . ILE B 1 105 ? -27.784 2.054   138.282 1.00 11.70  ? 105 ILE B N   1 
ATOM 1988 C CA  . ILE B 1 105 ? -26.923 3.255   138.129 1.00 11.70  ? 105 ILE B CA  1 
ATOM 1989 C C   . ILE B 1 105 ? -25.631 2.788   137.474 1.00 11.70  ? 105 ILE B C   1 
ATOM 1990 O O   . ILE B 1 105 ? -25.228 3.417   136.511 1.00 11.70  ? 105 ILE B O   1 
ATOM 1991 C CB  . ILE B 1 105 ? -26.677 3.964   139.471 1.00 11.70  ? 105 ILE B CB  1 
ATOM 1992 C CG1 . ILE B 1 105 ? -27.969 4.544   140.046 1.00 11.70  ? 105 ILE B CG1 1 
ATOM 1993 C CG2 . ILE B 1 105 ? -25.604 5.028   139.323 1.00 11.70  ? 105 ILE B CG2 1 
ATOM 1994 C CD1 . ILE B 1 105 ? -27.834 5.054   141.458 1.00 11.70  ? 105 ILE B CD1 1 
ATOM 1995 N N   . SER B 1 106 ? -25.058 1.679   137.924 1.00 11.23  ? 106 SER B N   1 
ATOM 1996 C CA  . SER B 1 106 ? -23.768 1.158   137.409 1.00 11.23  ? 106 SER B CA  1 
ATOM 1997 C C   . SER B 1 106 ? -23.923 0.596   136.002 1.00 11.23  ? 106 SER B C   1 
ATOM 1998 O O   . SER B 1 106 ? -22.944 0.614   135.274 1.00 11.23  ? 106 SER B O   1 
ATOM 1999 C CB  . SER B 1 106 ? -23.227 0.118   138.321 1.00 11.23  ? 106 SER B CB  1 
ATOM 2000 O OG  . SER B 1 106 ? -22.989 0.653   139.611 1.00 11.23  ? 106 SER B OG  1 
ATOM 2001 N N   . CYS B 1 107 ? -25.083 0.058   135.652 1.00 11.65  ? 107 CYS B N   1 
ATOM 2002 C CA  . CYS B 1 107 ? -25.334 -0.523  134.313 1.00 11.65  ? 107 CYS B CA  1 
ATOM 2003 C C   . CYS B 1 107 ? -25.534 0.631   133.344 1.00 11.65  ? 107 CYS B C   1 
ATOM 2004 O O   . CYS B 1 107 ? -25.300 0.438   132.150 1.00 11.65  ? 107 CYS B O   1 
ATOM 2005 C CB  . CYS B 1 107 ? -26.546 -1.438  134.301 1.00 11.65  ? 107 CYS B CB  1 
ATOM 2006 S SG  . CYS B 1 107 ? -26.188 -3.119  134.868 1.00 11.65  ? 107 CYS B SG  1 
ATOM 2007 N N   . LEU B 1 108 ? -25.942 1.785   133.854 1.00 12.17  ? 108 LEU B N   1 
ATOM 2008 C CA  . LEU B 1 108 ? -26.163 2.979   133.013 1.00 12.17  ? 108 LEU B CA  1 
ATOM 2009 C C   . LEU B 1 108 ? -24.815 3.642   132.783 1.00 12.17  ? 108 LEU B C   1 
ATOM 2010 O O   . LEU B 1 108 ? -24.611 4.165   131.685 1.00 12.17  ? 108 LEU B O   1 
ATOM 2011 C CB  . LEU B 1 108 ? -27.129 3.943   133.701 1.00 12.17  ? 108 LEU B CB  1 
ATOM 2012 C CG  . LEU B 1 108 ? -28.613 3.615   133.577 1.00 12.17  ? 108 LEU B CG  1 
ATOM 2013 C CD1 . LEU B 1 108 ? -29.440 4.620   134.354 1.00 12.17  ? 108 LEU B CD1 1 
ATOM 2014 C CD2 . LEU B 1 108 ? -29.052 3.591   132.125 1.00 12.17  ? 108 LEU B CD2 1 
ATOM 2015 N N   . THR B 1 109 ? -23.932 3.632   133.779 1.00 12.83  ? 109 THR B N   1 
ATOM 2016 C CA  . THR B 1 109 ? -22.652 4.325   133.631 1.00 12.83  ? 109 THR B CA  1 
ATOM 2017 C C   . THR B 1 109 ? -21.603 3.485   132.906 1.00 12.83  ? 109 THR B C   1 
ATOM 2018 O O   . THR B 1 109 ? -21.014 3.926   131.913 1.00 12.83  ? 109 THR B O   1 
ATOM 2019 C CB  . THR B 1 109 ? -22.130 4.734   135.012 1.00 12.83  ? 109 THR B CB  1 
ATOM 2020 O OG1 . THR B 1 109 ? -23.157 5.435   135.725 1.00 12.83  ? 109 THR B OG1 1 
ATOM 2021 C CG2 . THR B 1 109 ? -20.905 5.628   134.881 1.00 12.83  ? 109 THR B CG2 1 
ATOM 2022 N N   . PHE B 1 110 ? -21.355 2.270   133.396 1.00 12.52  ? 110 PHE B N   1 
ATOM 2023 C CA  . PHE B 1 110 ? -20.363 1.369   132.814 1.00 12.52  ? 110 PHE B CA  1 
ATOM 2024 C C   . PHE B 1 110 ? -20.869 0.581   131.612 1.00 12.52  ? 110 PHE B C   1 
ATOM 2025 O O   . PHE B 1 110 ? -20.077 0.257   130.723 1.00 12.52  ? 110 PHE B O   1 
ATOM 2026 C CB  . PHE B 1 110 ? -19.851 0.429   133.902 1.00 12.52  ? 110 PHE B CB  1 
ATOM 2027 C CG  . PHE B 1 110 ? -19.201 1.148   135.046 1.00 12.52  ? 110 PHE B CG  1 
ATOM 2028 C CD1 . PHE B 1 110 ? -17.984 1.787   134.876 1.00 12.52  ? 110 PHE B CD1 1 
ATOM 2029 C CD2 . PHE B 1 110 ? -19.815 1.211   136.285 1.00 12.52  ? 110 PHE B CD2 1 
ATOM 2030 C CE1 . PHE B 1 110 ? -17.386 2.460   135.921 1.00 12.52  ? 110 PHE B CE1 1 
ATOM 2031 C CE2 . PHE B 1 110 ? -19.222 1.882   137.335 1.00 12.52  ? 110 PHE B CE2 1 
ATOM 2032 C CZ  . PHE B 1 110 ? -18.007 2.509   137.151 1.00 12.52  ? 110 PHE B CZ  1 
ATOM 2033 N N   . GLY B 1 111 ? -22.160 0.263   131.556 1.00 12.08  ? 111 GLY B N   1 
ATOM 2034 C CA  . GLY B 1 111 ? -22.637 -0.722  130.602 1.00 12.08  ? 111 GLY B CA  1 
ATOM 2035 C C   . GLY B 1 111 ? -22.926 -2.072  131.229 1.00 12.08  ? 111 GLY B C   1 
ATOM 2036 O O   . GLY B 1 111 ? -22.184 -2.562  132.084 1.00 12.08  ? 111 GLY B O   1 
ATOM 2037 N N   . ARG B 1 112 ? -24.031 -2.673  130.785 1.00 12.52  ? 112 ARG B N   1 
ATOM 2038 C CA  . ARG B 1 112 ? -24.575 -3.868  131.424 1.00 12.52  ? 112 ARG B CA  1 
ATOM 2039 C C   . ARG B 1 112 ? -23.615 -5.056  131.372 1.00 12.52  ? 112 ARG B C   1 
ATOM 2040 O O   . ARG B 1 112 ? -23.372 -5.713  132.390 1.00 12.52  ? 112 ARG B O   1 
ATOM 2041 C CB  . ARG B 1 112 ? -25.900 -4.213  130.746 1.00 12.52  ? 112 ARG B CB  1 
ATOM 2042 C CG  . ARG B 1 112 ? -26.726 -5.286  131.416 1.00 12.52  ? 112 ARG B CG  1 
ATOM 2043 C CD  . ARG B 1 112 ? -28.004 -5.515  130.626 1.00 12.52  ? 112 ARG B CD  1 
ATOM 2044 N NE  . ARG B 1 112 ? -27.740 -6.061  129.300 1.00 12.52  ? 112 ARG B NE  1 
ATOM 2045 C CZ  . ARG B 1 112 ? -27.333 -7.300  129.061 1.00 12.52  ? 112 ARG B CZ  1 
ATOM 2046 N NH1 . ARG B 1 112 ? -27.255 -8.201  130.026 1.00 12.52  ? 112 ARG B NH1 1 
ATOM 2047 N NH2 . ARG B 1 112 ? -27.033 -7.655  127.815 1.00 12.52  ? 112 ARG B NH2 1 
ATOM 2048 N N   . GLU B 1 113 ? -23.058 -5.352  130.192 1.00 13.07  ? 113 GLU B N   1 
ATOM 2049 C CA  . GLU B 1 113 ? -22.115 -6.465  130.093 1.00 13.07  ? 113 GLU B CA  1 
ATOM 2050 C C   . GLU B 1 113 ? -20.877 -6.250  130.955 1.00 13.07  ? 113 GLU B C   1 
ATOM 2051 O O   . GLU B 1 113 ? -20.344 -7.208  131.529 1.00 13.07  ? 113 GLU B O   1 
ATOM 2052 C CB  . GLU B 1 113 ? -21.703 -6.670  128.633 1.00 13.07  ? 113 GLU B CB  1 
ATOM 2053 C CG  . GLU B 1 113 ? -22.836 -7.110  127.714 1.00 13.07  ? 113 GLU B CG  1 
ATOM 2054 C CD  . GLU B 1 113 ? -23.686 -5.949  127.223 1.00 13.07  ? 113 GLU B CD  1 
ATOM 2055 O OE1 . GLU B 1 113 ? -23.359 -4.786  127.546 1.00 13.07  ? 113 GLU B OE1 1 
ATOM 2056 O OE2 . GLU B 1 113 ? -24.686 -6.199  126.518 1.00 13.07  ? 113 GLU B OE2 1 
ATOM 2057 N N   . THR B 1 114 ? -20.397 -5.016  131.031 1.00 11.74  ? 114 THR B N   1 
ATOM 2058 C CA  . THR B 1 114 ? -19.236 -4.687  131.885 1.00 11.74  ? 114 THR B CA  1 
ATOM 2059 C C   . THR B 1 114 ? -19.616 -5.041  133.313 1.00 11.74  ? 114 THR B C   1 
ATOM 2060 O O   . THR B 1 114 ? -18.866 -5.792  133.943 1.00 11.74  ? 114 THR B O   1 
ATOM 2061 C CB  . THR B 1 114 ? -18.845 -3.215  131.762 1.00 11.74  ? 114 THR B CB  1 
ATOM 2062 O OG1 . THR B 1 114 ? -18.547 -2.955  130.391 1.00 11.74  ? 114 THR B OG1 1 
ATOM 2063 C CG2 . THR B 1 114 ? -17.659 -2.850  132.622 1.00 11.74  ? 114 THR B CG2 1 
ATOM 2064 N N   . VAL B 1 115 ? -20.767 -4.571  133.779 1.00 11.01  ? 115 VAL B N   1 
ATOM 2065 C CA  . VAL B 1 115 ? -21.209 -4.797  135.179 1.00 11.01  ? 115 VAL B CA  1 
ATOM 2066 C C   . VAL B 1 115 ? -21.286 -6.297  135.431 1.00 11.01  ? 115 VAL B C   1 
ATOM 2067 O O   . VAL B 1 115 ? -20.794 -6.713  136.468 1.00 11.01  ? 115 VAL B O   1 
ATOM 2068 C CB  . VAL B 1 115 ? -22.552 -4.113  135.466 1.00 11.01  ? 115 VAL B CB  1 
ATOM 2069 C CG1 . VAL B 1 115 ? -23.159 -4.592  136.773 1.00 11.01  ? 115 VAL B CG1 1 
ATOM 2070 C CG2 . VAL B 1 115 ? -22.424 -2.600  135.457 1.00 11.01  ? 115 VAL B CG2 1 
ATOM 2071 N N   . ILE B 1 116 ? -21.842 -7.083  134.518 1.00 11.34  ? 116 ILE B N   1 
ATOM 2072 C CA  . ILE B 1 116 ? -22.040 -8.545  134.734 1.00 11.34  ? 116 ILE B CA  1 
ATOM 2073 C C   . ILE B 1 116 ? -20.677 -9.230  134.844 1.00 11.34  ? 116 ILE B C   1 
ATOM 2074 O O   . ILE B 1 116 ? -20.511 -10.093 135.738 1.00 11.34  ? 116 ILE B O   1 
ATOM 2075 C CB  . ILE B 1 116 ? -22.911 -9.139  133.618 1.00 30.00  ? 116 ILE B CB  1 
ATOM 2076 C CG1 . ILE B 1 116 ? -24.334 -8.583  133.678 1.00 30.00  ? 116 ILE B CG1 1 
ATOM 2077 C CG2 . ILE B 1 116 ? -22.896 -10.655 133.673 1.00 30.00  ? 116 ILE B CG2 1 
ATOM 2078 C CD1 . ILE B 1 116 ? -25.136 -8.808  132.423 1.00 30.00  ? 116 ILE B CD1 1 
ATOM 2079 N N   . GLU B 1 117 ? -19.724 -8.859  133.999 1.00 10.84  ? 117 GLU B N   1 
ATOM 2080 C CA  . GLU B 1 117 ? -18.364 -9.446  134.036 1.00 10.84  ? 117 GLU B CA  1 
ATOM 2081 C C   . GLU B 1 117 ? -17.723 -9.081  135.369 1.00 10.84  ? 117 GLU B C   1 
ATOM 2082 O O   . GLU B 1 117 ? -17.098 -9.972  136.017 1.00 10.84  ? 117 GLU B O   1 
ATOM 2083 C CB  . GLU B 1 117 ? -17.546 -8.917  132.867 1.00 10.84  ? 117 GLU B CB  1 
ATOM 2084 C CG  . GLU B 1 117 ? -16.215 -9.617  132.700 1.00 10.84  ? 117 GLU B CG  1 
ATOM 2085 C CD  . GLU B 1 117 ? -15.408 -9.130  131.511 1.00 10.84  ? 117 GLU B CD  1 
ATOM 2086 O OE1 . GLU B 1 117 ? -14.261 -9.590  131.349 1.00 10.84  ? 117 GLU B OE1 1 
ATOM 2087 O OE2 . GLU B 1 117 ? -15.931 -8.295  130.749 1.00 10.84  ? 117 GLU B OE2 1 
ATOM 2088 N N   . TYR B 1 118 ? -17.886 -7.832  135.790 1.00 10.11  ? 118 TYR B N   1 
ATOM 2089 C CA  . TYR B 1 118 ? -17.326 -7.377  137.076 1.00 10.11  ? 118 TYR B CA  1 
ATOM 2090 C C   . TYR B 1 118 ? -17.899 -8.287  138.138 1.00 10.11  ? 118 TYR B C   1 
ATOM 2091 O O   . TYR B 1 118 ? -17.126 -8.830  138.886 1.00 10.11  ? 118 TYR B O   1 
ATOM 2092 C CB  . TYR B 1 118 ? -17.691 -5.935  137.405 1.00 10.11  ? 118 TYR B CB  1 
ATOM 2093 C CG  . TYR B 1 118 ? -17.259 -5.499  138.779 1.00 10.11  ? 118 TYR B CG  1 
ATOM 2094 C CD1 . TYR B 1 118 ? -15.936 -5.196  139.045 1.00 10.11  ? 118 TYR B CD1 1 
ATOM 2095 C CD2 . TYR B 1 118 ? -18.168 -5.399  139.815 1.00 10.11  ? 118 TYR B CD2 1 
ATOM 2096 C CE1 . TYR B 1 118 ? -15.528 -4.799  140.305 1.00 10.11  ? 118 TYR B CE1 1 
ATOM 2097 C CE2 . TYR B 1 118 ? -17.778 -5.002  141.081 1.00 10.11  ? 118 TYR B CE2 1 
ATOM 2098 C CZ  . TYR B 1 118 ? -16.452 -4.702  141.326 1.00 10.11  ? 118 TYR B CZ  1 
ATOM 2099 O OH  . TYR B 1 118 ? -16.056 -4.311  142.570 1.00 10.11  ? 118 TYR B OH  1 
ATOM 2100 N N   . LEU B 1 119 ? -19.207 -8.485  138.142 1.00 10.08  ? 119 LEU B N   1 
ATOM 2101 C CA  . LEU B 1 119 ? -19.877 -9.300  139.175 1.00 10.08  ? 119 LEU B CA  1 
ATOM 2102 C C   . LEU B 1 119 ? -19.246 -10.685 139.172 1.00 10.08  ? 119 LEU B C   1 
ATOM 2103 O O   . LEU B 1 119 ? -18.794 -11.096 140.224 1.00 10.08  ? 119 LEU B O   1 
ATOM 2104 C CB  . LEU B 1 119 ? -21.377 -9.351  138.889 1.00 10.08  ? 119 LEU B CB  1 
ATOM 2105 C CG  . LEU B 1 119 ? -22.154 -8.082  139.233 1.00 10.08  ? 119 LEU B CG  1 
ATOM 2106 C CD1 . LEU B 1 119 ? -23.579 -8.170  138.719 1.00 10.08  ? 119 LEU B CD1 1 
ATOM 2107 C CD2 . LEU B 1 119 ? -22.146 -7.828  140.730 1.00 10.08  ? 119 LEU B CD2 1 
ATOM 2108 N N   . VAL B 1 120 ? -19.139 -11.334 138.020 1.00 9.49   ? 120 VAL B N   1 
ATOM 2109 C CA  . VAL B 1 120 ? -18.562 -12.706 137.927 1.00 9.49   ? 120 VAL B CA  1 
ATOM 2110 C C   . VAL B 1 120 ? -17.176 -12.728 138.575 1.00 9.49   ? 120 VAL B C   1 
ATOM 2111 O O   . VAL B 1 120 ? -16.938 -13.576 139.480 1.00 9.49   ? 120 VAL B O   1 
ATOM 2112 C CB  . VAL B 1 120 ? -18.492 -13.170 136.466 1.00 9.49   ? 120 VAL B CB  1 
ATOM 2113 C CG1 . VAL B 1 120 ? -17.650 -14.422 136.315 1.00 9.49   ? 120 VAL B CG1 1 
ATOM 2114 C CG2 . VAL B 1 120 ? -19.875 -13.377 135.878 1.00 9.49   ? 120 VAL B CG2 1 
ATOM 2115 N N   . SER B 1 121 ? -16.286 -11.820 138.182 1.00 9.43   ? 121 SER B N   1 
ATOM 2116 C CA  . SER B 1 121 ? -14.893 -11.822 138.702 1.00 9.43   ? 121 SER B CA  1 
ATOM 2117 C C   . SER B 1 121 ? -14.860 -11.515 140.201 1.00 9.43   ? 121 SER B C   1 
ATOM 2118 O O   . SER B 1 121 ? -14.063 -12.153 140.924 1.00 9.43   ? 121 SER B O   1 
ATOM 2119 C CB  . SER B 1 121 ? -14.059 -10.857 137.943 1.00 9.43   ? 121 SER B CB  1 
ATOM 2120 O OG  . SER B 1 121 ? -14.030 -11.199 136.567 1.00 9.43   ? 121 SER B OG  1 
ATOM 2121 N N   . PHE B 1 122 ? -15.671 -10.576 140.666 1.00 9.75   ? 122 PHE B N   1 
ATOM 2122 C CA  . PHE B 1 122 ? -15.694 -10.167 142.086 1.00 9.75   ? 122 PHE B CA  1 
ATOM 2123 C C   . PHE B 1 122 ? -16.167 -11.362 142.878 1.00 9.75   ? 122 PHE B C   1 
ATOM 2124 O O   . PHE B 1 122 ? -15.717 -11.527 143.993 1.00 9.75   ? 122 PHE B O   1 
ATOM 2125 C CB  . PHE B 1 122 ? -16.617 -8.978  142.333 1.00 9.75   ? 122 PHE B CB  1 
ATOM 2126 C CG  . PHE B 1 122 ? -16.702 -8.548  143.774 1.00 9.75   ? 122 PHE B CG  1 
ATOM 2127 C CD1 . PHE B 1 122 ? -17.482 -9.247  144.676 1.00 9.75   ? 122 PHE B CD1 1 
ATOM 2128 C CD2 . PHE B 1 122 ? -15.999 -7.445  144.224 1.00 9.75   ? 122 PHE B CD2 1 
ATOM 2129 C CE1 . PHE B 1 122 ? -17.556 -8.854  146.003 1.00 9.75   ? 122 PHE B CE1 1 
ATOM 2130 C CE2 . PHE B 1 122 ? -16.076 -7.052  145.551 1.00 9.75   ? 122 PHE B CE2 1 
ATOM 2131 C CZ  . PHE B 1 122 ? -16.853 -7.757  146.437 1.00 9.75   ? 122 PHE B CZ  1 
ATOM 2132 N N   . GLY B 1 123 ? -17.067 -12.144 142.308 1.00 9.17   ? 123 GLY B N   1 
ATOM 2133 C CA  . GLY B 1 123 ? -17.577 -13.353 142.960 1.00 9.17   ? 123 GLY B CA  1 
ATOM 2134 C C   . GLY B 1 123 ? -16.465 -14.352 143.082 1.00 9.17   ? 123 GLY B C   1 
ATOM 2135 O O   . GLY B 1 123 ? -16.234 -14.830 144.179 1.00 9.17   ? 123 GLY B O   1 
ATOM 2136 N N   . VAL B 1 124 ? -15.753 -14.608 141.995 1.00 8.86   ? 124 VAL B N   1 
ATOM 2137 C CA  . VAL B 1 124 ? -14.581 -15.517 142.069 1.00 8.86   ? 124 VAL B CA  1 
ATOM 2138 C C   . VAL B 1 124 ? -13.693 -15.034 143.207 1.00 8.86   ? 124 VAL B C   1 
ATOM 2139 O O   . VAL B 1 124 ? -13.220 -15.882 143.949 1.00 8.86   ? 124 VAL B O   1 
ATOM 2140 C CB  . VAL B 1 124 ? -13.803 -15.571 140.751 1.00 8.86   ? 124 VAL B CB  1 
ATOM 2141 C CG1 . VAL B 1 124 ? -12.478 -16.292 140.913 1.00 8.86   ? 124 VAL B CG1 1 
ATOM 2142 C CG2 . VAL B 1 124 ? -14.632 -16.202 139.650 1.00 8.86   ? 124 VAL B CG2 1 
ATOM 2143 N N   . TRP B 1 125 ? -13.496 -13.726 143.355 1.00 10.23  ? 125 TRP B N   1 
ATOM 2144 C CA  . TRP B 1 125 ? -12.574 -13.171 144.380 1.00 10.23  ? 125 TRP B CA  1 
ATOM 2145 C C   . TRP B 1 125 ? -13.108 -13.377 145.790 1.00 10.23  ? 125 TRP B C   1 
ATOM 2146 O O   . TRP B 1 125 ? -12.344 -13.855 146.630 1.00 10.23  ? 125 TRP B O   1 
ATOM 2147 C CB  . TRP B 1 125 ? -12.359 -11.686 144.115 1.00 10.23  ? 125 TRP B CB  1 
ATOM 2148 C CG  . TRP B 1 125 ? -11.412 -11.010 145.053 1.00 10.23  ? 125 TRP B CG  1 
ATOM 2149 C CD1 . TRP B 1 125 ? -10.058 -10.940 144.931 1.00 10.23  ? 125 TRP B CD1 1 
ATOM 2150 C CD2 . TRP B 1 125 ? -11.749 -10.272 146.238 1.00 10.23  ? 125 TRP B CD2 1 
ATOM 2151 N NE1 . TRP B 1 125 ? -9.527  -10.222 145.967 1.00 10.23  ? 125 TRP B NE1 1 
ATOM 2152 C CE2 . TRP B 1 125 ? -10.539 -9.798  146.784 1.00 10.23  ? 125 TRP B CE2 1 
ATOM 2153 C CE3 . TRP B 1 125 ? -12.947 -9.972  146.892 1.00 10.23  ? 125 TRP B CE3 1 
ATOM 2154 C CZ2 . TRP B 1 125 ? -10.497 -9.044  147.953 1.00 10.23  ? 125 TRP B CZ2 1 
ATOM 2155 C CZ3 . TRP B 1 125 ? -12.904 -9.226  148.048 1.00 10.23  ? 125 TRP B CZ3 1 
ATOM 2156 C CH2 . TRP B 1 125 ? -11.695 -8.770  148.569 1.00 10.23  ? 125 TRP B CH2 1 
ATOM 2157 N N   . ILE B 1 126 ? -14.362 -13.034 146.046 1.00 10.37  ? 126 ILE B N   1 
ATOM 2158 C CA  . ILE B 1 126 ? -14.964 -13.088 147.402 1.00 10.37  ? 126 ILE B CA  1 
ATOM 2159 C C   . ILE B 1 126 ? -15.116 -14.548 147.779 1.00 10.37  ? 126 ILE B C   1 
ATOM 2160 O O   . ILE B 1 126 ? -15.084 -14.845 148.982 1.00 10.37  ? 126 ILE B O   1 
ATOM 2161 C CB  . ILE B 1 126 ? -16.310 -12.351 147.439 1.00 10.37  ? 126 ILE B CB  1 
ATOM 2162 C CG1 . ILE B 1 126 ? -16.713 -11.991 148.868 1.00 10.37  ? 126 ILE B CG1 1 
ATOM 2163 C CG2 . ILE B 1 126 ? -17.391 -13.151 146.732 1.00 10.37  ? 126 ILE B CG2 1 
ATOM 2164 C CD1 . ILE B 1 126 ? -15.802 -10.985 149.519 1.00 10.37  ? 126 ILE B CD1 1 
ATOM 2165 N N   . ARG B 1 127 ? -15.270 -15.439 146.800 1.00 9.88   ? 127 ARG B N   1 
ATOM 2166 C CA  . ARG B 1 127 ? -15.306 -16.853 147.167 1.00 9.88   ? 127 ARG B CA  1 
ATOM 2167 C C   . ARG B 1 127 ? -13.937 -17.394 147.575 1.00 9.88   ? 127 ARG B C   1 
ATOM 2168 O O   . ARG B 1 127 ? -13.869 -18.360 148.342 1.00 9.88   ? 127 ARG B O   1 
ATOM 2169 C CB  . ARG B 1 127 ? -15.878 -17.680 146.016 1.00 9.88   ? 127 ARG B CB  1 
ATOM 2170 C CG  . ARG B 1 127 ? -17.389 -17.570 145.887 1.00 9.88   ? 127 ARG B CG  1 
ATOM 2171 C CD  . ARG B 1 127 ? -17.955 -18.622 144.949 1.00 9.88   ? 127 ARG B CD  1 
ATOM 2172 N NE  . ARG B 1 127 ? -17.398 -18.517 143.606 1.00 9.88   ? 127 ARG B NE  1 
ATOM 2173 C CZ  . ARG B 1 127 ? -17.937 -17.815 142.617 1.00 9.88   ? 127 ARG B CZ  1 
ATOM 2174 N NH1 . ARG B 1 127 ? -19.025 -17.083 142.798 1.00 9.88   ? 127 ARG B NH1 1 
ATOM 2175 N NH2 . ARG B 1 127 ? -17.383 -17.866 141.410 1.00 9.88   ? 127 ARG B NH2 1 
ATOM 2176 N N   . THR B 1 128 ? -12.848 -16.809 147.089 1.00 11.59  ? 128 THR B N   1 
ATOM 2177 C CA  . THR B 1 128 ? -11.527 -17.244 147.529 1.00 11.59  ? 128 THR B CA  1 
ATOM 2178 C C   . THR B 1 128 ? -11.341 -16.974 149.023 1.00 11.59  ? 128 THR B C   1 
ATOM 2179 O O   . THR B 1 128 ? -11.625 -15.862 149.488 1.00 11.59  ? 128 THR B O   1 
ATOM 2180 C CB  . THR B 1 128 ? -10.437 -16.528 146.733 1.00 11.59  ? 128 THR B CB  1 
ATOM 2181 O OG1 . THR B 1 128 ? -10.650 -16.736 145.332 1.00 11.59  ? 128 THR B OG1 1 
ATOM 2182 C CG2 . THR B 1 128 ? -9.062  -17.058 147.114 1.00 11.59  ? 128 THR B CG2 1 
ATOM 2183 N N   . PRO B 1 129 ? -10.877 -17.953 149.803 1.00 12.52  ? 129 PRO B N   1 
ATOM 2184 C CA  . PRO B 1 129 ? -10.653 -17.710 151.226 1.00 12.52  ? 129 PRO B CA  1 
ATOM 2185 C C   . PRO B 1 129 ? -9.596  -16.649 151.449 1.00 12.52  ? 129 PRO B C   1 
ATOM 2186 O O   . PRO B 1 129 ? -8.657  -16.501 150.643 1.00 12.52  ? 129 PRO B O   1 
ATOM 2187 C CB  . PRO B 1 129 ? -10.198 -19.080 151.751 1.00 12.52  ? 129 PRO B CB  1 
ATOM 2188 C CG  . PRO B 1 129 ? -10.752 -20.056 150.791 1.00 12.52  ? 129 PRO B CG  1 
ATOM 2189 C CD  . PRO B 1 129 ? -10.666 -19.369 149.462 1.00 12.52  ? 129 PRO B CD  1 
ATOM 2190 N N   . PRO B 1 130 ? -9.705  -15.879 152.538 1.00 13.45  ? 130 PRO B N   1 
ATOM 2191 C CA  . PRO B 1 130 ? -8.801  -14.731 152.730 1.00 13.45  ? 130 PRO B CA  1 
ATOM 2192 C C   . PRO B 1 130 ? -7.320  -15.085 152.725 1.00 13.45  ? 130 PRO B C   1 
ATOM 2193 O O   . PRO B 1 130 ? -6.499  -14.247 152.331 1.00 13.45  ? 130 PRO B O   1 
ATOM 2194 C CB  . PRO B 1 130 ? -9.231  -14.181 154.097 1.00 13.45  ? 130 PRO B CB  1 
ATOM 2195 C CG  . PRO B 1 130 ? -10.653 -14.554 154.213 1.00 13.45  ? 130 PRO B CG  1 
ATOM 2196 C CD  . PRO B 1 130 ? -10.746 -15.918 153.580 1.00 13.45  ? 130 PRO B CD  1 
ATOM 2197 N N   . ALA B 1 131 ? -6.951  -16.296 153.149 1.00 12.84  ? 131 ALA B N   1 
ATOM 2198 C CA  . ALA B 1 131 ? -5.543  -16.688 153.141 1.00 12.84  ? 131 ALA B CA  1 
ATOM 2199 C C   . ALA B 1 131 ? -4.966  -16.703 151.733 1.00 12.84  ? 131 ALA B C   1 
ATOM 2200 O O   . ALA B 1 131 ? -3.756  -16.524 151.557 1.00 12.84  ? 131 ALA B O   1 
ATOM 2201 C CB  . ALA B 1 131 ? -5.379  -18.062 153.791 1.00 12.84  ? 131 ALA B CB  1 
ATOM 2202 N N   . TYR B 1 132 ? -5.808  -16.912 150.724 1.00 12.36  ? 132 TYR B N   1 
ATOM 2203 C CA  . TYR B 1 132 ? -5.374  -17.017 149.341 1.00 12.36  ? 132 TYR B CA  1 
ATOM 2204 C C   . TYR B 1 132 ? -5.908  -15.885 148.482 1.00 12.36  ? 132 TYR B C   1 
ATOM 2205 O O   . TYR B 1 132 ? -5.385  -15.661 147.384 1.00 12.36  ? 132 TYR B O   1 
ATOM 2206 C CB  . TYR B 1 132 ? -5.821  -18.360 148.742 1.00 12.36  ? 132 TYR B CB  1 
ATOM 2207 C CG  . TYR B 1 132 ? -5.488  -19.541 149.624 1.00 12.36  ? 132 TYR B CG  1 
ATOM 2208 C CD1 . TYR B 1 132 ? -4.171  -19.874 149.909 1.00 12.36  ? 132 TYR B CD1 1 
ATOM 2209 C CD2 . TYR B 1 132 ? -6.494  -20.315 150.186 1.00 12.36  ? 132 TYR B CD2 1 
ATOM 2210 C CE1 . TYR B 1 132 ? -3.865  -20.949 150.719 1.00 12.36  ? 132 TYR B CE1 1 
ATOM 2211 C CE2 . TYR B 1 132 ? -6.197  -21.392 150.996 1.00 12.36  ? 132 TYR B CE2 1 
ATOM 2212 C CZ  . TYR B 1 132 ? -4.882  -21.704 151.262 1.00 12.36  ? 132 TYR B CZ  1 
ATOM 2213 O OH  . TYR B 1 132 ? -4.584  -22.771 152.077 1.00 12.36  ? 132 TYR B OH  1 
ATOM 2214 N N   . ARG B 1 133 ? -6.925  -15.181 148.950 1.00 12.42  ? 133 ARG B N   1 
ATOM 2215 C CA  . ARG B 1 133 ? -7.488  -14.050 148.229 1.00 12.42  ? 133 ARG B CA  1 
ATOM 2216 C C   . ARG B 1 133 ? -6.461  -12.925 148.124 1.00 12.42  ? 133 ARG B C   1 
ATOM 2217 O O   . ARG B 1 133 ? -5.839  -12.566 149.130 1.00 12.42  ? 133 ARG B O   1 
ATOM 2218 C CB  . ARG B 1 133 ? -8.728  -13.581 148.980 1.00 12.42  ? 133 ARG B CB  1 
ATOM 2219 C CG  . ARG B 1 133 ? -9.588  -12.561 148.288 1.00 12.42  ? 133 ARG B CG  1 
ATOM 2220 C CD  . ARG B 1 133 ? -10.623 -12.039 149.268 1.00 12.42  ? 133 ARG B CD  1 
ATOM 2221 N NE  . ARG B 1 133 ? -11.497 -13.098 149.755 1.00 12.42  ? 133 ARG B NE  1 
ATOM 2222 C CZ  . ARG B 1 133 ? -12.347 -12.963 150.763 1.00 12.42  ? 133 ARG B CZ  1 
ATOM 2223 N NH1 . ARG B 1 133 ? -12.452 -11.826 151.432 1.00 12.42  ? 133 ARG B NH1 1 
ATOM 2224 N NH2 . ARG B 1 133 ? -13.110 -13.995 151.111 1.00 12.42  ? 133 ARG B NH2 1 
ATOM 2225 N N   . PRO B 1 134 ? -6.250  -12.346 146.942 1.00 12.55  ? 134 PRO B N   1 
ATOM 2226 C CA  . PRO B 1 134 ? -5.446  -11.121 146.846 1.00 12.55  ? 134 PRO B CA  1 
ATOM 2227 C C   . PRO B 1 134 ? -6.041  -10.000 147.678 1.00 12.55  ? 134 PRO B C   1 
ATOM 2228 O O   . PRO B 1 134 ? -7.270  -9.856  147.756 1.00 12.55  ? 134 PRO B O   1 
ATOM 2229 C CB  . PRO B 1 134 ? -5.484  -10.787 145.345 1.00 12.55  ? 134 PRO B CB  1 
ATOM 2230 C CG  . PRO B 1 134 ? -5.724  -12.093 144.686 1.00 12.55  ? 134 PRO B CG  1 
ATOM 2231 C CD  . PRO B 1 134 ? -6.661  -12.820 145.611 1.00 12.55  ? 134 PRO B CD  1 
ATOM 2232 N N   . PRO B 1 135 ? -5.202  -9.179  148.317 1.00 13.49  ? 135 PRO B N   1 
ATOM 2233 C CA  . PRO B 1 135 ? -5.702  -8.301  149.388 1.00 13.49  ? 135 PRO B CA  1 
ATOM 2234 C C   . PRO B 1 135 ? -6.626  -7.187  148.917 1.00 13.49  ? 135 PRO B C   1 
ATOM 2235 O O   . PRO B 1 135 ? -7.383  -6.661  149.742 1.00 13.49  ? 135 PRO B O   1 
ATOM 2236 C CB  . PRO B 1 135 ? -4.413  -7.729  150.001 1.00 13.49  ? 135 PRO B CB  1 
ATOM 2237 C CG  . PRO B 1 135 ? -3.416  -7.801  148.899 1.00 13.49  ? 135 PRO B CG  1 
ATOM 2238 C CD  . PRO B 1 135 ? -3.741  -9.072  148.171 1.00 13.49  ? 135 PRO B CD  1 
ATOM 2239 N N   . ASN B 1 136 ? -6.603  -6.808  147.641 1.00 12.98  ? 136 ASN B N   1 
ATOM 2240 C CA  . ASN B 1 136 ? -7.479  -5.764  147.123 1.00 12.98  ? 136 ASN B CA  1 
ATOM 2241 C C   . ASN B 1 136 ? -8.542  -6.368  146.217 1.00 12.98  ? 136 ASN B C   1 
ATOM 2242 O O   . ASN B 1 136 ? -8.232  -7.161  145.323 1.00 12.98  ? 136 ASN B O   1 
ATOM 2243 C CB  . ASN B 1 136 ? -6.676  -4.712  146.356 1.00 12.98  ? 136 ASN B CB  1 
ATOM 2244 C CG  . ASN B 1 136 ? -5.741  -3.927  147.254 1.00 12.98  ? 136 ASN B CG  1 
ATOM 2245 O OD1 . ASN B 1 136 ? -6.168  -3.331  148.244 1.00 12.98  ? 136 ASN B OD1 1 
ATOM 2246 N ND2 . ASN B 1 136 ? -4.456  -3.919  146.913 1.00 12.98  ? 136 ASN B ND2 1 
ATOM 2247 N N   . ALA B 1 137 ? -9.795  -5.984  146.456 1.00 10.66  ? 137 ALA B N   1 
ATOM 2248 C CA  . ALA B 1 137 ? -10.906 -6.404  145.624 1.00 10.66  ? 137 ALA B CA  1 
ATOM 2249 C C   . ALA B 1 137 ? -10.800 -5.824  144.215 1.00 10.66  ? 137 ALA B C   1 
ATOM 2250 O O   . ALA B 1 137 ? -10.160 -4.791  144.001 1.00 10.66  ? 137 ALA B O   1 
ATOM 2251 C CB  . ALA B 1 137 ? -12.226 -5.980  146.259 1.00 10.66  ? 137 ALA B CB  1 
ATOM 2252 N N   . PRO B 1 138 ? -11.425 -6.474  143.235 1.00 10.24  ? 138 PRO B N   1 
ATOM 2253 C CA  . PRO B 1 138 ? -11.607 -5.839  141.925 1.00 10.24  ? 138 PRO B CA  1 
ATOM 2254 C C   . PRO B 1 138 ? -12.410 -4.552  142.050 1.00 10.24  ? 138 PRO B C   1 
ATOM 2255 O O   . PRO B 1 138 ? -13.336 -4.453  142.858 1.00 10.24  ? 138 PRO B O   1 
ATOM 2256 C CB  . PRO B 1 138 ? -12.354 -6.902  141.111 1.00 10.24  ? 138 PRO B CB  1 
ATOM 2257 C CG  . PRO B 1 138 ? -12.057 -8.188  141.803 1.00 10.24  ? 138 PRO B CG  1 
ATOM 2258 C CD  . PRO B 1 138 ? -11.991 -7.832  143.255 1.00 10.24  ? 138 PRO B CD  1 
ATOM 2259 N N   . ILE B 1 139 ? -12.052 -3.562  141.235 1.00 11.91  ? 139 ILE B N   1 
ATOM 2260 C CA  . ILE B 1 139 ? -12.661 -2.239  141.281 1.00 11.91  ? 139 ILE B CA  1 
ATOM 2261 C C   . ILE B 1 139 ? -13.221 -1.907  139.905 1.00 11.91  ? 139 ILE B C   1 
ATOM 2262 O O   . ILE B 1 139 ? -12.569 -2.146  138.883 1.00 11.91  ? 139 ILE B O   1 
ATOM 2263 C CB  . ILE B 1 139 ? -11.639 -1.170  141.726 1.00 11.91  ? 139 ILE B CB  1 
ATOM 2264 C CG1 . ILE B 1 139 ? -11.361 -1.294  143.223 1.00 11.91  ? 139 ILE B CG1 1 
ATOM 2265 C CG2 . ILE B 1 139 ? -12.136 0.241   141.409 1.00 11.91  ? 139 ILE B CG2 1 
ATOM 2266 C CD1 . ILE B 1 139 ? -10.142 -0.524  143.682 1.00 11.91  ? 139 ILE B CD1 1 
ATOM 2267 N N   . LEU B 1 140 ? -14.434 -1.360  139.887 1.00 12.18  ? 140 LEU B N   1 
ATOM 2268 C CA  . LEU B 1 140 ? -15.049 -0.802  138.687 1.00 12.18  ? 140 LEU B CA  1 
ATOM 2269 C C   . LEU B 1 140 ? -15.082 0.713   138.853 1.00 12.18  ? 140 LEU B C   1 
ATOM 2270 O O   . LEU B 1 140 ? -15.882 1.238   139.637 1.00 12.18  ? 140 LEU B O   1 
ATOM 2271 C CB  . LEU B 1 140 ? -16.453 -1.369  138.489 1.00 12.18  ? 140 LEU B CB  1 
ATOM 2272 C CG  . LEU B 1 140 ? -17.085 -1.291  137.097 1.00 12.18  ? 140 LEU B CG  1 
ATOM 2273 C CD1 . LEU B 1 140 ? -16.171 -1.888  136.037 1.00 12.18  ? 140 LEU B CD1 1 
ATOM 2274 C CD2 . LEU B 1 140 ? -18.438 -1.984  137.095 1.00 12.18  ? 140 LEU B CD2 1 
ATOM 2275 N N   . SER B 1 141 ? -14.219 1.412   138.119 1.00 15.94  ? 141 SER B N   1 
ATOM 2276 C CA  . SER B 1 141 ? -14.078 2.854   138.261 1.00 15.94  ? 141 SER B CA  1 
ATOM 2277 C C   . SER B 1 141 ? -13.882 3.496   136.896 1.00 15.94  ? 141 SER B C   1 
ATOM 2278 O O   . SER B 1 141 ? -13.459 2.850   135.934 1.00 15.94  ? 141 SER B O   1 
ATOM 2279 C CB  . SER B 1 141 ? -12.903 3.216   139.179 1.00 15.94  ? 141 SER B CB  1 
ATOM 2280 O OG  . SER B 1 141 ? -12.684 4.615   139.196 1.00 15.94  ? 141 SER B OG  1 
ATOM 2281 N N   . THR B 1 142 ? -14.201 4.787   136.825 1.00 18.91  ? 142 THR B N   1 
ATOM 2282 C CA  . THR B 1 142 ? -14.027 5.576   135.613 1.00 18.91  ? 142 THR B CA  1 
ATOM 2283 C C   . THR B 1 142 ? -12.677 6.285   135.563 1.00 18.91  ? 142 THR B C   1 
ATOM 2284 O O   . THR B 1 142 ? -12.427 7.038   134.615 1.00 18.91  ? 142 THR B O   1 
ATOM 2285 C CB  . THR B 1 142 ? -15.150 6.612   135.491 1.00 18.91  ? 142 THR B CB  1 
ATOM 2286 O OG1 . THR B 1 142 ? -15.183 7.431   136.666 1.00 18.91  ? 142 THR B OG1 1 
ATOM 2287 C CG2 . THR B 1 142 ? -16.496 5.925   135.314 1.00 18.91  ? 142 THR B CG2 1 
ATOM 2288 N N   . LEU B 1 143 ? -11.842 6.099   136.593 1.00 20.15  ? 143 LEU B N   1 
ATOM 2289 C CA  . LEU B 1 143 ? -10.517 6.770   136.689 1.00 20.15  ? 143 LEU B CA  1 
ATOM 2290 C C   . LEU B 1 143 ? -9.400  5.726   136.614 1.00 20.15  ? 143 LEU B C   1 
ATOM 2291 O O   . LEU B 1 143 ? -9.465  4.737   137.368 1.00 20.15  ? 143 LEU B O   1 
ATOM 2292 C CB  . LEU B 1 143 ? -10.445 7.543   138.009 1.00 20.15  ? 143 LEU B CB  1 
ATOM 2293 C CG  . LEU B 1 143 ? -11.680 8.372   138.352 1.00 20.15  ? 143 LEU B CG  1 
ATOM 2294 C CD1 . LEU B 1 143 ? -11.425 9.239   139.571 1.00 20.15  ? 143 LEU B CD1 1 
ATOM 2295 C CD2 . LEU B 1 143 ? -12.104 9.227   137.169 1.00 20.15  ? 143 LEU B CD2 1 
ATOM 2296 N N   . PRO B 1 144 ? -8.380  5.904   135.744 1.00 26.29  ? 144 PRO B N   1 
ATOM 2297 C CA  . PRO B 1 144 ? -7.251  4.976   135.669 1.00 26.29  ? 144 PRO B CA  1 
ATOM 2298 C C   . PRO B 1 144 ? -6.195  5.245   136.750 1.00 26.29  ? 144 PRO B C   1 
ATOM 2299 O O   . PRO B 1 144 ? -5.555  4.297   137.168 1.00 26.29  ? 144 PRO B O   1 
ATOM 2300 C CB  . PRO B 1 144 ? -6.668  5.271   134.282 1.00 26.29  ? 144 PRO B CB  1 
ATOM 2301 C CG  . PRO B 1 144 ? -6.928  6.748   134.093 1.00 26.29  ? 144 PRO B CG  1 
ATOM 2302 C CD  . PRO B 1 144 ? -8.253  7.002   134.783 1.00 26.29  ? 144 PRO B CD  1 
ATOM 2303 N N   . GLU B 1 145 ? -6.060  6.486   137.208 1.00 26.92  ? 145 GLU B N   1 
ATOM 2304 C CA  . GLU B 1 145 ? -5.027  6.851   138.216 1.00 26.92  ? 145 GLU B CA  1 
ATOM 2305 C C   . GLU B 1 145 ? -5.503  8.056   139.025 1.00 26.92  ? 145 GLU B C   1 
ATOM 2306 O O   . GLU B 1 145 ? -4.643  8.823   139.488 1.00 26.92  ? 145 GLU B O   1 
ATOM 2307 C CB  . GLU B 1 145 ? -3.705  7.148   137.513 1.00 26.92  ? 145 GLU B CB  1 
ATOM 2308 C CG  . GLU B 1 145 ? -3.081  5.932   136.860 1.00 26.92  ? 145 GLU B CG  1 
ATOM 2309 C CD  . GLU B 1 145 ? -1.803  6.229   136.098 1.00 26.92  ? 145 GLU B CD  1 
ATOM 2310 O OE1 . GLU B 1 145 ? -1.491  7.420   135.911 1.00 26.92  ? 145 GLU B OE1 1 
ATOM 2311 O OE2 . GLU B 1 145 ? -1.121  5.265   135.703 1.00 26.92  ? 145 GLU B OE2 1 
ATOM 2312 N N   . THR B 1 146 ? -6.812  8.223   139.190 1.00 20.35  ? 146 THR B N   1 
ATOM 2313 C CA  . THR B 1 146 ? -7.407  9.347   139.965 1.00 20.35  ? 146 THR B CA  1 
ATOM 2314 C C   . THR B 1 146 ? -6.666  10.646  139.637 1.00 20.35  ? 146 THR B C   1 
ATOM 2315 O O   . THR B 1 146 ? -6.318  11.367  140.588 1.00 20.35  ? 146 THR B O   1 
ATOM 2316 C CB  . THR B 1 146 ? -7.421  9.024   141.465 1.00 20.35  ? 146 THR B CB  1 
ATOM 2317 O OG1 . THR B 1 146 ? -6.096  8.697   141.883 1.00 20.35  ? 146 THR B OG1 1 
ATOM 2318 C CG2 . THR B 1 146 ? -8.354  7.880   141.788 1.00 20.35  ? 146 THR B CG2 1 
ATOM 2319 N N   . THR B 1 147 ? -6.405  10.924  138.359 1.00 22.00  ? 147 THR B N   1 
ATOM 2320 C CA  . THR B 1 147 ? -5.781  12.197  137.909 1.00 22.00  ? 147 THR B CA  1 
ATOM 2321 C C   . THR B 1 147 ? -6.436  12.596  136.589 1.00 22.00  ? 147 THR B C   1 
ATOM 2322 O O   . THR B 1 147 ? -6.400  11.770  135.660 1.00 22.00  ? 147 THR B O   1 
ATOM 2323 C CB  . THR B 1 147 ? -4.265  12.069  137.750 1.00 22.00  ? 147 THR B CB  1 
ATOM 2324 O OG1 . THR B 1 147 ? -3.722  11.713  139.021 1.00 22.00  ? 147 THR B OG1 1 
ATOM 2325 C CG2 . THR B 1 147 ? -3.627  13.345  137.249 1.00 22.00  ? 147 THR B CG2 1 
ATOM 2326 N N   . VAL B 1 148 ? -6.998  13.799  136.496 1.00 19.45  ? 148 VAL B N   1 
ATOM 2327 C CA  . VAL B 1 148 ? -7.746  14.240  135.284 1.00 19.45  ? 148 VAL B CA  1 
ATOM 2328 C C   . VAL B 1 148 ? -6.893  15.236  134.494 1.00 19.45  ? 148 VAL B C   1 
ATOM 2329 O O   . VAL B 1 148 ? -6.668  16.333  135.017 1.00 19.45  ? 148 VAL B O   1 
ATOM 2330 C CB  . VAL B 1 148 ? -9.104  14.837  135.694 1.00 19.45  ? 148 VAL B CB  1 
ATOM 2331 C CG1 . VAL B 1 148 ? -9.816  15.492  134.525 1.00 19.45  ? 148 VAL B CG1 1 
ATOM 2332 C CG2 . VAL B 1 148 ? -9.994  13.796  136.350 1.00 19.45  ? 148 VAL B CG2 1 
ATOM 2333 N N   . VAL B 1 149 ? -6.455  14.878  133.282 1.00 24.62  ? 149 VAL B N   1 
ATOM 2334 C CA  . VAL B 1 149 ? -5.646  15.775  132.401 1.00 24.62  ? 149 VAL B CA  1 
ATOM 2335 C C   . VAL B 1 149 ? -6.488  16.143  131.176 1.00 24.62  ? 149 VAL B C   1 
ATOM 2336 O O   . VAL B 1 149 ? -7.389  15.356  130.837 1.00 24.62  ? 149 VAL B O   1 
ATOM 2337 C CB  . VAL B 1 149 ? -4.307  15.124  132.006 1.00 24.62  ? 149 VAL B CB  1 
ATOM 2338 C CG1 . VAL B 1 149 ? -3.399  14.946  133.211 1.00 24.62  ? 149 VAL B CG1 1 
ATOM 2339 C CG2 . VAL B 1 149 ? -4.508  13.802  131.285 1.00 24.62  ? 149 VAL B CG2 1 
ATOM 2340 N N   . ARG B 1 150 ? -6.204  17.274  130.526 1.00 27.77  ? 150 ARG B N   1 
ATOM 2341 C CA  . ARG B 1 150 ? -6.986  17.763  129.399 1.00 27.77  ? 150 ARG B CA  1 
ATOM 2342 C C   . ARG B 1 150 ? -6.953  16.731  128.278 1.00 27.77  ? 150 ARG B C   1 
ATOM 2343 O O   . ARG B 1 150 ? -5.892  16.203  127.936 1.00 27.77  ? 150 ARG B O   1 
ATOM 2344 C CB  . ARG B 1 150 ? -6.431  19.104  128.921 1.00 27.77  ? 150 ARG B CB  1 
ATOM 2345 C CG  . ARG B 1 150 ? -7.298  19.826  127.904 1.00 27.77  ? 150 ARG B CG  1 
ATOM 2346 C CD  . ARG B 1 150 ? -6.766  21.226  127.646 1.00 27.77  ? 150 ARG B CD  1 
ATOM 2347 N NE  . ARG B 1 150 ? -7.678  22.025  126.832 1.00 27.77  ? 150 ARG B NE  1 
ATOM 2348 C CZ  . ARG B 1 150 ? -8.058  23.266  127.110 1.00 27.77  ? 150 ARG B CZ  1 
ATOM 2349 N NH1 . ARG B 1 150 ? -7.610  23.910  128.177 1.00 27.77  ? 150 ARG B NH1 1 
ATOM 2350 N NH2 . ARG B 1 150 ? -8.903  23.883  126.290 1.00 27.77  ? 150 ARG B NH2 1 
ATOM 2351 N N   . ARG B 1 151 ? -8.118  16.443  127.704 1.00 47.35  ? 151 ARG B N   1 
ATOM 2352 C CA  . ARG B 1 151 ? -8.216  15.348  126.749 1.00 47.35  ? 151 ARG B CA  1 
ATOM 2353 C C   . ARG B 1 151 ? -7.339  15.615  125.529 1.00 47.35  ? 151 ARG B C   1 
ATOM 2354 O O   . ARG B 1 151 ? -7.161  16.759  125.097 1.00 47.35  ? 151 ARG B O   1 
ATOM 2355 C CB  . ARG B 1 151 ? -9.666  15.141  126.315 1.00 47.35  ? 151 ARG B CB  1 
ATOM 2356 C CG  . ARG B 1 151 ? -9.954  13.739  125.800 1.00 47.35  ? 151 ARG B CG  1 
ATOM 2357 C CD  . ARG B 1 151 ? -11.356 13.625  125.225 1.00 47.35  ? 151 ARG B CD  1 
ATOM 2358 N NE  . ARG B 1 151 ? -11.495 14.354  123.970 1.00 47.35  ? 151 ARG B NE  1 
ATOM 2359 C CZ  . ARG B 1 151 ? -11.061 13.920  122.795 1.00 47.35  ? 151 ARG B CZ  1 
ATOM 2360 N NH1 . ARG B 1 151 ? -10.554 12.705  122.650 1.00 47.35  ? 151 ARG B NH1 1 
ATOM 2361 N NH2 . ARG B 1 151 ? -11.144 14.721  121.737 1.00 47.35  ? 151 ARG B NH2 1 
ATOM 2362 N N   . ARG B 1 152 ? -6.792  14.538  124.970 1.00 55.23  ? 152 ARG B N   1 
ATOM 2363 C CA  . ARG B 1 152 ? -6.104  14.620  123.694 1.00 55.23  ? 152 ARG B CA  1 
ATOM 2364 C C   . ARG B 1 152 ? -7.079  15.023  122.588 1.00 55.23  ? 152 ARG B C   1 
ATOM 2365 O O   . ARG B 1 152 ? -8.302  15.004  122.755 1.00 55.23  ? 152 ARG B O   1 
ATOM 2366 C CB  . ARG B 1 152 ? -5.442  13.282  123.363 1.00 55.23  ? 152 ARG B CB  1 
ATOM 2367 C CG  . ARG B 1 152 ? -4.378  12.863  124.366 1.00 55.23  ? 152 ARG B CG  1 
ATOM 2368 C CD  . ARG B 1 152 ? -3.609  11.639  123.897 1.00 55.23  ? 152 ARG B CD  1 
ATOM 2369 N NE  . ARG B 1 152 ? -4.469  10.468  123.772 1.00 55.23  ? 152 ARG B NE  1 
ATOM 2370 C CZ  . ARG B 1 152 ? -4.302  9.497   122.884 1.00 55.23  ? 152 ARG B CZ  1 
ATOM 2371 N NH1 . ARG B 1 152 ? -3.292  9.505   122.028 1.00 55.23  ? 152 ARG B NH1 1 
ATOM 2372 N NH2 . ARG B 1 152 ? -5.169  8.488   122.853 1.00 55.23  ? 152 ARG B NH2 1 
ATOM 2373 N N   . GLY B 1 153 ? -6.518  15.390  121.441 1.00 58.05  ? 153 GLY B N   1 
ATOM 2374 C CA  . GLY B 1 153 ? -7.314  15.762  120.287 1.00 58.05  ? 153 GLY B CA  1 
ATOM 2375 C C   . GLY B 1 153 ? -8.086  14.593  119.706 1.00 58.05  ? 153 GLY B C   1 
ATOM 2376 O O   . GLY B 1 153 ? -9.300  14.668  119.524 1.00 58.05  ? 153 GLY B O   1 
ATOM 2377 N N   . MET C 1 1   ? -37.075 36.153  138.124 1.00 19.17  ? 1   MET C N   1 
ATOM 2378 C CA  . MET C 1 1   ? -36.387 35.269  137.138 1.00 19.17  ? 1   MET C CA  1 
ATOM 2379 C C   . MET C 1 1   ? -35.554 34.204  137.839 1.00 19.17  ? 1   MET C C   1 
ATOM 2380 O O   . MET C 1 1   ? -34.989 34.444  138.906 1.00 19.17  ? 1   MET C O   1 
ATOM 2381 C CB  . MET C 1 1   ? -35.486 36.082  136.206 1.00 19.17  ? 1   MET C CB  1 
ATOM 2382 C CG  . MET C 1 1   ? -36.248 36.936  135.226 1.00 19.17  ? 1   MET C CG  1 
ATOM 2383 S SD  . MET C 1 1   ? -35.191 37.898  134.127 1.00 19.17  ? 1   MET C SD  1 
ATOM 2384 C CE  . MET C 1 1   ? -34.990 39.408  135.067 1.00 19.17  ? 1   MET C CE  1 
ATOM 2385 N N   . ASP C 1 2   ? -35.475 33.028  137.220 1.00 20.64  ? 2   ASP C N   1 
ATOM 2386 C CA  . ASP C 1 2   ? -34.813 31.860  137.792 1.00 20.64  ? 2   ASP C CA  1 
ATOM 2387 C C   . ASP C 1 2   ? -33.649 31.512  136.878 1.00 20.64  ? 2   ASP C C   1 
ATOM 2388 O O   . ASP C 1 2   ? -33.853 31.067  135.743 1.00 20.64  ? 2   ASP C O   1 
ATOM 2389 C CB  . ASP C 1 2   ? -35.781 30.684  137.927 1.00 20.64  ? 2   ASP C CB  1 
ATOM 2390 C CG  . ASP C 1 2   ? -35.165 29.490  138.633 1.00 20.64  ? 2   ASP C CG  1 
ATOM 2391 O OD1 . ASP C 1 2   ? -34.135 29.663  139.320 1.00 20.64  ? 2   ASP C OD1 1 
ATOM 2392 O OD2 . ASP C 1 2   ? -35.718 28.379  138.509 1.00 20.64  ? 2   ASP C OD2 1 
ATOM 2393 N N   . ILE C 1 3   ? -32.430 31.698  137.378 1.00 17.16  ? 3   ILE C N   1 
ATOM 2394 C CA  . ILE C 1 3   ? -31.217 31.555  136.586 1.00 17.16  ? 3   ILE C CA  1 
ATOM 2395 C C   . ILE C 1 3   ? -30.228 30.713  137.379 1.00 17.16  ? 3   ILE C C   1 
ATOM 2396 O O   . ILE C 1 3   ? -30.039 30.937  138.579 1.00 17.16  ? 3   ILE C O   1 
ATOM 2397 C CB  . ILE C 1 3   ? -30.608 32.928  136.234 1.00 17.16  ? 3   ILE C CB  1 
ATOM 2398 C CG1 . ILE C 1 3   ? -31.623 33.768  135.453 1.00 17.16  ? 3   ILE C CG1 1 
ATOM 2399 C CG2 . ILE C 1 3   ? -29.328 32.759  135.420 1.00 17.16  ? 3   ILE C CG2 1 
ATOM 2400 C CD1 . ILE C 1 3   ? -31.168 35.183  135.172 1.00 17.16  ? 3   ILE C CD1 1 
ATOM 2401 N N   . ASP C 1 4   ? -29.600 29.744  136.707 1.00 17.27  ? 4   ASP C N   1 
ATOM 2402 C CA  . ASP C 1 4   ? -28.346 29.206  137.209 1.00 17.27  ? 4   ASP C CA  1 
ATOM 2403 C C   . ASP C 1 4   ? -27.176 29.853  136.485 1.00 17.27  ? 4   ASP C C   1 
ATOM 2404 O O   . ASP C 1 4   ? -27.207 29.963  135.250 1.00 17.27  ? 4   ASP C O   1 
ATOM 2405 C CB  . ASP C 1 4   ? -28.292 27.693  137.015 1.00 17.27  ? 4   ASP C CB  1 
ATOM 2406 C CG  . ASP C 1 4   ? -29.321 26.958  137.852 1.00 17.27  ? 4   ASP C CG  1 
ATOM 2407 O OD1 . ASP C 1 4   ? -29.703 27.478  138.921 1.00 17.27  ? 4   ASP C OD1 1 
ATOM 2408 O OD2 . ASP C 1 4   ? -29.743 25.856  137.442 1.00 17.27  ? 4   ASP C OD2 1 
ATOM 2409 N N   . PRO C 1 5   ? -26.140 30.295  137.200 1.00 14.69  ? 5   PRO C N   1 
ATOM 2410 C CA  . PRO C 1 5   ? -24.939 30.801  136.516 1.00 14.69  ? 5   PRO C CA  1 
ATOM 2411 C C   . PRO C 1 5   ? -24.264 29.769  135.632 1.00 14.69  ? 5   PRO C C   1 
ATOM 2412 O O   . PRO C 1 5   ? -23.555 30.143  134.691 1.00 14.69  ? 5   PRO C O   1 
ATOM 2413 C CB  . PRO C 1 5   ? -24.023 31.230  137.673 1.00 14.69  ? 5   PRO C CB  1 
ATOM 2414 C CG  . PRO C 1 5   ? -24.492 30.453  138.849 1.00 14.69  ? 5   PRO C CG  1 
ATOM 2415 C CD  . PRO C 1 5   ? -25.964 30.250  138.662 1.00 14.69  ? 5   PRO C CD  1 
ATOM 2416 N N   . TYR C 1 6   ? -24.463 28.484  135.911 1.00 13.62  ? 6   TYR C N   1 
ATOM 2417 C CA  . TYR C 1 6   ? -23.814 27.397  135.194 1.00 13.62  ? 6   TYR C CA  1 
ATOM 2418 C C   . TYR C 1 6   ? -24.571 26.916  133.963 1.00 13.62  ? 6   TYR C C   1 
ATOM 2419 O O   . TYR C 1 6   ? -24.005 26.143  133.182 1.00 13.62  ? 6   TYR C O   1 
ATOM 2420 C CB  . TYR C 1 6   ? -23.610 26.223  136.154 1.00 13.62  ? 6   TYR C CB  1 
ATOM 2421 C CG  . TYR C 1 6   ? -23.007 26.638  137.474 1.00 13.62  ? 6   TYR C CG  1 
ATOM 2422 C CD1 . TYR C 1 6   ? -21.712 27.129  137.544 1.00 13.62  ? 6   TYR C CD1 1 
ATOM 2423 C CD2 . TYR C 1 6   ? -23.737 26.544  138.651 1.00 13.62  ? 6   TYR C CD2 1 
ATOM 2424 C CE1 . TYR C 1 6   ? -21.155 27.504  138.749 1.00 13.62  ? 6   TYR C CE1 1 
ATOM 2425 C CE2 . TYR C 1 6   ? -23.191 26.920  139.860 1.00 13.62  ? 6   TYR C CE2 1 
ATOM 2426 C CZ  . TYR C 1 6   ? -21.901 27.401  139.903 1.00 13.62  ? 6   TYR C CZ  1 
ATOM 2427 O OH  . TYR C 1 6   ? -21.355 27.786  141.106 1.00 13.62  ? 6   TYR C OH  1 
ATOM 2428 N N   . LYS C 1 7   ? -25.818 27.341  133.756 1.00 16.06  ? 7   LYS C N   1 
ATOM 2429 C CA  . LYS C 1 7   ? -26.617 26.740  132.692 1.00 16.06  ? 7   LYS C CA  1 
ATOM 2430 C C   . LYS C 1 7   ? -26.048 27.045  131.311 1.00 16.06  ? 7   LYS C C   1 
ATOM 2431 O O   . LYS C 1 7   ? -25.985 26.155  130.456 1.00 16.06  ? 7   LYS C O   1 
ATOM 2432 C CB  . LYS C 1 7   ? -28.057 27.247  132.778 1.00 16.06  ? 7   LYS C CB  1 
ATOM 2433 C CG  . LYS C 1 7   ? -29.024 26.558  131.825 1.00 16.06  ? 7   LYS C CG  1 
ATOM 2434 C CD  . LYS C 1 7   ? -30.467 26.934  132.127 1.00 16.06  ? 7   LYS C CD  1 
ATOM 2435 C CE  . LYS C 1 7   ? -31.424 26.371  131.088 1.00 16.06  ? 7   LYS C CE  1 
ATOM 2436 N NZ  . LYS C 1 7   ? -31.475 24.885  131.108 1.00 16.06  ? 7   LYS C NZ  1 
ATOM 2437 N N   . GLU C 1 8   ? -25.626 28.287  131.067 1.00 15.00  ? 8   GLU C N   1 
ATOM 2438 C CA  . GLU C 1 8   ? -24.969 28.588  129.799 1.00 15.00  ? 8   GLU C CA  1 
ATOM 2439 C C   . GLU C 1 8   ? -23.647 27.851  129.626 1.00 15.00  ? 8   GLU C C   1 
ATOM 2440 O O   . GLU C 1 8   ? -23.176 27.711  128.494 1.00 15.00  ? 8   GLU C O   1 
ATOM 2441 C CB  . GLU C 1 8   ? -24.744 30.094  129.663 1.00 15.00  ? 8   GLU C CB  1 
ATOM 2442 C CG  . GLU C 1 8   ? -23.823 30.697  130.713 1.00 15.00  ? 8   GLU C CG  1 
ATOM 2443 C CD  . GLU C 1 8   ? -23.803 32.212  130.658 1.00 15.00  ? 8   GLU C CD  1 
ATOM 2444 O OE1 . GLU C 1 8   ? -23.697 32.848  131.728 1.00 15.00  ? 8   GLU C OE1 1 
ATOM 2445 O OE2 . GLU C 1 8   ? -23.886 32.767  129.544 1.00 15.00  ? 8   GLU C OE2 1 
ATOM 2446 N N   . PHE C 1 9   ? -23.035 27.382  130.714 1.00 13.48  ? 9   PHE C N   1 
ATOM 2447 C CA  . PHE C 1 9   ? -21.807 26.601  130.643 1.00 13.48  ? 9   PHE C CA  1 
ATOM 2448 C C   . PHE C 1 9   ? -22.038 25.097  130.748 1.00 13.48  ? 9   PHE C C   1 
ATOM 2449 O O   . PHE C 1 9   ? -21.080 24.348  130.953 1.00 13.48  ? 9   PHE C O   1 
ATOM 2450 C CB  . PHE C 1 9   ? -20.843 27.071  131.732 1.00 13.48  ? 9   PHE C CB  1 
ATOM 2451 C CG  . PHE C 1 9   ? -20.494 28.528  131.628 1.00 13.48  ? 9   PHE C CG  1 
ATOM 2452 C CD1 . PHE C 1 9   ? -19.555 28.962  130.708 1.00 13.48  ? 9   PHE C CD1 1 
ATOM 2453 C CD2 . PHE C 1 9   ? -21.120 29.465  132.430 1.00 13.48  ? 9   PHE C CD2 1 
ATOM 2454 C CE1 . PHE C 1 9   ? -19.239 30.301  130.600 1.00 13.48  ? 9   PHE C CE1 1 
ATOM 2455 C CE2 . PHE C 1 9   ? -20.804 30.806  132.329 1.00 13.48  ? 9   PHE C CE2 1 
ATOM 2456 C CZ  . PHE C 1 9   ? -19.862 31.223  131.413 1.00 13.48  ? 9   PHE C CZ  1 
ATOM 2457 N N   . GLY C 1 10  ? -23.281 24.640  130.615 1.00 14.29  ? 10  GLY C N   1 
ATOM 2458 C CA  . GLY C 1 10  ? -23.583 23.224  130.595 1.00 14.29  ? 10  GLY C CA  1 
ATOM 2459 C C   . GLY C 1 10  ? -23.550 22.522  131.937 1.00 14.29  ? 10  GLY C C   1 
ATOM 2460 O O   . GLY C 1 10  ? -23.832 21.318  131.989 1.00 14.29  ? 10  GLY C O   1 
ATOM 2461 N N   . ALA C 1 11  ? -23.211 23.220  133.018 1.00 14.26  ? 11  ALA C N   1 
ATOM 2462 C CA  . ALA C 1 11  ? -23.246 22.661  134.359 1.00 14.26  ? 11  ALA C CA  1 
ATOM 2463 C C   . ALA C 1 11  ? -24.531 23.091  135.067 1.00 14.26  ? 11  ALA C C   1 
ATOM 2464 O O   . ALA C 1 11  ? -25.365 23.810  134.514 1.00 14.26  ? 11  ALA C O   1 
ATOM 2465 C CB  . ALA C 1 11  ? -21.999 23.079  135.142 1.00 14.26  ? 11  ALA C CB  1 
ATOM 2466 N N   . THR C 1 12  ? -24.694 22.638  136.311 1.00 14.45  ? 12  THR C N   1 
ATOM 2467 C CA  . THR C 1 12  ? -25.843 23.017  137.121 1.00 14.45  ? 12  THR C CA  1 
ATOM 2468 C C   . THR C 1 12  ? -25.409 23.219  138.567 1.00 14.45  ? 12  THR C C   1 
ATOM 2469 O O   . THR C 1 12  ? -24.373 22.717  139.008 1.00 14.45  ? 12  THR C O   1 
ATOM 2470 C CB  . THR C 1 12  ? -26.962 21.965  137.061 1.00 14.45  ? 12  THR C CB  1 
ATOM 2471 O OG1 . THR C 1 12  ? -26.565 20.795  137.787 1.00 14.45  ? 12  THR C OG1 1 
ATOM 2472 C CG2 . THR C 1 12  ? -27.273 21.587  135.620 1.00 14.45  ? 12  THR C CG2 1 
ATOM 2473 N N   . VAL C 1 13  ? -26.226 23.980  139.299 1.00 14.31  ? 13  VAL C N   1 
ATOM 2474 C CA  . VAL C 1 13  ? -26.002 24.189  140.728 1.00 14.31  ? 13  VAL C CA  1 
ATOM 2475 C C   . VAL C 1 13  ? -26.011 22.863  141.477 1.00 14.31  ? 13  VAL C C   1 
ATOM 2476 O O   . VAL C 1 13  ? -25.264 22.674  142.443 1.00 14.31  ? 13  VAL C O   1 
ATOM 2477 C CB  . VAL C 1 13  ? -27.058 25.159  141.289 1.00 14.31  ? 13  VAL C CB  1 
ATOM 2478 C CG1 . VAL C 1 13  ? -26.976 25.230  142.810 1.00 14.31  ? 13  VAL C CG1 1 
ATOM 2479 C CG2 . VAL C 1 13  ? -26.894 26.540  140.680 1.00 14.31  ? 13  VAL C CG2 1 
ATOM 2480 N N   . GLU C 1 14  ? -26.863 21.929  141.052 1.00 15.93  ? 14  GLU C N   1 
ATOM 2481 C CA  . GLU C 1 14  ? -26.843 20.579  141.608 1.00 15.93  ? 14  GLU C CA  1 
ATOM 2482 C C   . GLU C 1 14  ? -25.490 19.902  141.417 1.00 15.93  ? 14  GLU C C   1 
ATOM 2483 O O   . GLU C 1 14  ? -24.944 19.303  142.351 1.00 15.93  ? 14  GLU C O   1 
ATOM 2484 C CB  . GLU C 1 14  ? -27.954 19.742  140.973 1.00 15.93  ? 14  GLU C CB  1 
ATOM 2485 C CG  . GLU C 1 14  ? -27.984 18.296  141.439 1.00 15.93  ? 14  GLU C CG  1 
ATOM 2486 C CD  . GLU C 1 14  ? -29.160 17.534  140.874 1.00 15.93  ? 14  GLU C CD  1 
ATOM 2487 O OE1 . GLU C 1 14  ? -29.195 17.307  139.647 1.00 15.93  ? 14  GLU C OE1 1 
ATOM 2488 O OE2 . GLU C 1 14  ? -30.048 17.156  141.665 1.00 15.93  ? 14  GLU C OE2 1 
ATOM 2489 N N   . LEU C 1 15  ? -24.935 19.982  140.208 1.00 14.22  ? 15  LEU C N   1 
ATOM 2490 C CA  . LEU C 1 15  ? -23.647 19.346  139.946 1.00 14.22  ? 15  LEU C CA  1 
ATOM 2491 C C   . LEU C 1 15  ? -22.520 19.951  140.778 1.00 14.22  ? 15  LEU C C   1 
ATOM 2492 O O   . LEU C 1 15  ? -21.646 19.224  141.265 1.00 14.22  ? 15  LEU C O   1 
ATOM 2493 C CB  . LEU C 1 15  ? -23.323 19.446  138.454 1.00 14.22  ? 15  LEU C CB  1 
ATOM 2494 C CG  . LEU C 1 15  ? -22.046 18.751  137.974 1.00 14.22  ? 15  LEU C CG  1 
ATOM 2495 C CD1 . LEU C 1 15  ? -22.140 17.247  138.171 1.00 14.22  ? 15  LEU C CD1 1 
ATOM 2496 C CD2 . LEU C 1 15  ? -21.765 19.074  136.512 1.00 14.22  ? 15  LEU C CD2 1 
ATOM 2497 N N   . LEU C 1 16  ? -22.506 21.276  140.953 1.00 13.61  ? 16  LEU C N   1 
ATOM 2498 C CA  . LEU C 1 16  ? -21.499 21.874  141.828 1.00 13.61  ? 16  LEU C CA  1 
ATOM 2499 C C   . LEU C 1 16  ? -21.731 21.512  143.292 1.00 13.61  ? 16  LEU C C   1 
ATOM 2500 O O   . LEU C 1 16  ? -20.772 21.283  144.040 1.00 13.61  ? 16  LEU C O   1 
ATOM 2501 C CB  . LEU C 1 16  ? -21.498 23.394  141.655 1.00 13.61  ? 16  LEU C CB  1 
ATOM 2502 C CG  . LEU C 1 16  ? -20.601 23.974  140.558 1.00 13.61  ? 16  LEU C CG  1 
ATOM 2503 C CD1 . LEU C 1 16  ? -19.131 23.725  140.859 1.00 13.61  ? 16  LEU C CD1 1 
ATOM 2504 C CD2 . LEU C 1 16  ? -20.974 23.403  139.200 1.00 13.61  ? 16  LEU C CD2 1 
ATOM 2505 N N   . SER C 1 17  ? -22.993 21.461  143.720 1.00 14.64  ? 17  SER C N   1 
ATOM 2506 C CA  . SER C 1 17  ? -23.323 21.014  145.070 1.00 14.64  ? 17  SER C CA  1 
ATOM 2507 C C   . SER C 1 17  ? -22.894 19.575  145.316 1.00 14.64  ? 17  SER C C   1 
ATOM 2508 O O   . SER C 1 17  ? -22.644 19.189  146.462 1.00 14.64  ? 17  SER C O   1 
ATOM 2509 C CB  . SER C 1 17  ? -24.824 21.164  145.312 1.00 14.64  ? 17  SER C CB  1 
ATOM 2510 O OG  . SER C 1 17  ? -25.283 22.437  144.891 1.00 14.64  ? 17  SER C OG  1 
ATOM 2511 N N   . PHE C 1 18  ? -22.823 18.767  144.258 1.00 13.50  ? 18  PHE C N   1 
ATOM 2512 C CA  . PHE C 1 18  ? -22.444 17.366  144.407 1.00 13.50  ? 18  PHE C CA  1 
ATOM 2513 C C   . PHE C 1 18  ? -21.104 17.217  145.127 1.00 13.50  ? 18  PHE C C   1 
ATOM 2514 O O   . PHE C 1 18  ? -20.963 16.363  146.011 1.00 13.50  ? 18  PHE C O   1 
ATOM 2515 C CB  . PHE C 1 18  ? -22.407 16.723  143.016 1.00 13.50  ? 18  PHE C CB  1 
ATOM 2516 C CG  . PHE C 1 18  ? -22.434 15.217  143.017 1.00 13.50  ? 18  PHE C CG  1 
ATOM 2517 C CD1 . PHE C 1 18  ? -23.346 14.522  143.794 1.00 13.50  ? 18  PHE C CD1 1 
ATOM 2518 C CD2 . PHE C 1 18  ? -21.605 14.500  142.171 1.00 13.50  ? 18  PHE C CD2 1 
ATOM 2519 C CE1 . PHE C 1 18  ? -23.398 13.141  143.759 1.00 13.50  ? 18  PHE C CE1 1 
ATOM 2520 C CE2 . PHE C 1 18  ? -21.649 13.117  142.141 1.00 13.50  ? 18  PHE C CE2 1 
ATOM 2521 C CZ  . PHE C 1 18  ? -22.548 12.440  142.934 1.00 13.50  ? 18  PHE C CZ  1 
ATOM 2522 N N   . LEU C 1 19  ? -20.111 18.029  144.770 1.00 14.06  ? 19  LEU C N   1 
ATOM 2523 C CA  . LEU C 1 19  ? -18.863 18.057  145.530 1.00 14.06  ? 19  LEU C CA  1 
ATOM 2524 C C   . LEU C 1 19  ? -19.070 18.688  146.909 1.00 14.06  ? 19  LEU C C   1 
ATOM 2525 O O   . LEU C 1 19  ? -19.852 19.633  147.048 1.00 14.06  ? 19  LEU C O   1 
ATOM 2526 C CB  . LEU C 1 19  ? -17.779 18.820  144.769 1.00 14.06  ? 19  LEU C CB  1 
ATOM 2527 C CG  . LEU C 1 19  ? -17.021 17.971  143.744 1.00 14.06  ? 19  LEU C CG  1 
ATOM 2528 C CD1 . LEU C 1 19  ? -17.960 17.455  142.666 1.00 14.06  ? 19  LEU C CD1 1 
ATOM 2529 C CD2 . LEU C 1 19  ? -15.860 18.741  143.125 1.00 14.06  ? 19  LEU C CD2 1 
ATOM 2530 N N   . PRO C 1 20  ? -18.389 18.187  147.942 1.00 14.66  ? 20  PRO C N   1 
ATOM 2531 C CA  . PRO C 1 20  ? -18.565 18.752  149.285 1.00 14.66  ? 20  PRO C CA  1 
ATOM 2532 C C   . PRO C 1 20  ? -18.036 20.177  149.400 1.00 14.66  ? 20  PRO C C   1 
ATOM 2533 O O   . PRO C 1 20  ? -17.069 20.568  148.742 1.00 14.66  ? 20  PRO C O   1 
ATOM 2534 C CB  . PRO C 1 20  ? -17.772 17.789  150.180 1.00 14.66  ? 20  PRO C CB  1 
ATOM 2535 C CG  . PRO C 1 20  ? -16.730 17.227  149.285 1.00 14.66  ? 20  PRO C CG  1 
ATOM 2536 C CD  . PRO C 1 20  ? -17.385 17.112  147.933 1.00 14.66  ? 20  PRO C CD  1 
ATOM 2537 N N   . SER C 1 21  ? -18.699 20.953  150.261 1.00 15.62  ? 21  SER C N   1 
ATOM 2538 C CA  . SER C 1 21  ? -18.342 22.355  150.472 1.00 15.62  ? 21  SER C CA  1 
ATOM 2539 C C   . SER C 1 21  ? -16.890 22.541  150.908 1.00 15.62  ? 21  SER C C   1 
ATOM 2540 O O   . SER C 1 21  ? -16.271 23.559  150.577 1.00 15.62  ? 21  SER C O   1 
ATOM 2541 C CB  . SER C 1 21  ? -19.279 22.974  151.508 1.00 15.62  ? 21  SER C CB  1 
ATOM 2542 O OG  . SER C 1 21  ? -20.557 23.224  150.953 1.00 15.62  ? 21  SER C OG  1 
ATOM 2543 N N   . ASP C 1 22  ? -16.334 21.584  151.652 1.00 17.04  ? 22  ASP C N   1 
ATOM 2544 C CA  . ASP C 1 22  ? -14.945 21.667  152.093 1.00 17.04  ? 22  ASP C CA  1 
ATOM 2545 C C   . ASP C 1 22  ? -13.944 21.583  150.949 1.00 17.04  ? 22  ASP C C   1 
ATOM 2546 O O   . ASP C 1 22  ? -12.785 21.973  151.130 1.00 17.04  ? 22  ASP C O   1 
ATOM 2547 C CB  . ASP C 1 22  ? -14.653 20.555  153.101 1.00 17.04  ? 22  ASP C CB  1 
ATOM 2548 C CG  . ASP C 1 22  ? -15.430 20.720  154.390 1.00 17.04  ? 22  ASP C CG  1 
ATOM 2549 O OD1 . ASP C 1 22  ? -15.773 21.870  154.737 1.00 17.04  ? 22  ASP C OD1 1 
ATOM 2550 O OD2 . ASP C 1 22  ? -15.700 19.700  155.057 1.00 17.04  ? 22  ASP C OD2 1 
ATOM 2551 N N   . PHE C 1 23  ? -14.355 21.091  149.781 1.00 13.76  ? 23  PHE C N   1 
ATOM 2552 C CA  . PHE C 1 23  ? -13.403 20.842  148.703 1.00 13.76  ? 23  PHE C CA  1 
ATOM 2553 C C   . PHE C 1 23  ? -12.819 22.137  148.149 1.00 13.76  ? 23  PHE C C   1 
ATOM 2554 O O   . PHE C 1 23  ? -11.609 22.226  147.914 1.00 13.76  ? 23  PHE C O   1 
ATOM 2555 C CB  . PHE C 1 23  ? -14.083 20.041  147.594 1.00 13.76  ? 23  PHE C CB  1 
ATOM 2556 C CG  . PHE C 1 23  ? -13.264 19.929  146.342 1.00 13.76  ? 23  PHE C CG  1 
ATOM 2557 C CD1 . PHE C 1 23  ? -12.205 19.043  146.268 1.00 13.76  ? 23  PHE C CD1 1 
ATOM 2558 C CD2 . PHE C 1 23  ? -13.544 20.727  145.244 1.00 13.76  ? 23  PHE C CD2 1 
ATOM 2559 C CE1 . PHE C 1 23  ? -11.444 18.947  145.120 1.00 13.76  ? 23  PHE C CE1 1 
ATOM 2560 C CE2 . PHE C 1 23  ? -12.791 20.631  144.092 1.00 13.76  ? 23  PHE C CE2 1 
ATOM 2561 C CZ  . PHE C 1 23  ? -11.741 19.738  144.029 1.00 13.76  ? 23  PHE C CZ  1 
ATOM 2562 N N   . PHE C 1 24  ? -13.655 23.146  147.927 1.00 12.98  ? 24  PHE C N   1 
ATOM 2563 C CA  . PHE C 1 24  ? -13.221 24.328  147.195 1.00 12.98  ? 24  PHE C CA  1 
ATOM 2564 C C   . PHE C 1 24  ? -12.180 25.123  147.988 1.00 12.98  ? 24  PHE C C   1 
ATOM 2565 O O   . PHE C 1 24  ? -12.313 25.281  149.205 1.00 12.98  ? 24  PHE C O   1 
ATOM 2566 C CB  . PHE C 1 24  ? -14.430 25.202  146.875 1.00 12.98  ? 24  PHE C CB  1 
ATOM 2567 C CG  . PHE C 1 24  ? -15.508 24.469  146.131 1.00 12.98  ? 24  PHE C CG  1 
ATOM 2568 C CD1 . PHE C 1 24  ? -15.444 24.319  144.758 1.00 12.98  ? 24  PHE C CD1 1 
ATOM 2569 C CD2 . PHE C 1 24  ? -16.574 23.908  146.811 1.00 12.98  ? 24  PHE C CD2 1 
ATOM 2570 C CE1 . PHE C 1 24  ? -16.429 23.635  144.074 1.00 12.98  ? 24  PHE C CE1 1 
ATOM 2571 C CE2 . PHE C 1 24  ? -17.563 23.224  146.135 1.00 12.98  ? 24  PHE C CE2 1 
ATOM 2572 C CZ  . PHE C 1 24  ? -17.487 23.082  144.765 1.00 12.98  ? 24  PHE C CZ  1 
ATOM 2573 N N   . PRO C 1 25  ? -11.134 25.631  147.329 1.00 12.71  ? 25  PRO C N   1 
ATOM 2574 C CA  . PRO C 1 25  ? -10.132 26.453  148.022 1.00 12.71  ? 25  PRO C CA  1 
ATOM 2575 C C   . PRO C 1 25  ? -10.721 27.723  148.619 1.00 12.71  ? 25  PRO C C   1 
ATOM 2576 O O   . PRO C 1 25  ? -11.877 28.087  148.394 1.00 12.71  ? 25  PRO C O   1 
ATOM 2577 C CB  . PRO C 1 25  ? -9.112  26.782  146.922 1.00 12.71  ? 25  PRO C CB  1 
ATOM 2578 C CG  . PRO C 1 25  ? -9.298  25.728  145.901 1.00 12.71  ? 25  PRO C CG  1 
ATOM 2579 C CD  . PRO C 1 25  ? -10.761 25.410  145.921 1.00 12.71  ? 25  PRO C CD  1 
ATOM 2580 N N   . SER C 1 26  ? -9.886  28.409  149.400 1.00 13.93  ? 26  SER C N   1 
ATOM 2581 C CA  . SER C 1 26  ? -10.245 29.701  149.963 1.00 13.93  ? 26  SER C CA  1 
ATOM 2582 C C   . SER C 1 26  ? -10.390 30.756  148.867 1.00 13.93  ? 26  SER C C   1 
ATOM 2583 O O   . SER C 1 26  ? -9.888  30.610  147.750 1.00 13.93  ? 26  SER C O   1 
ATOM 2584 C CB  . SER C 1 26  ? -9.198  30.148  150.984 1.00 13.93  ? 26  SER C CB  1 
ATOM 2585 O OG  . SER C 1 26  ? -7.984  30.507  150.350 1.00 13.93  ? 26  SER C OG  1 
ATOM 2586 N N   . VAL C 1 27  ? -11.090 31.839  149.210 1.00 14.33  ? 27  VAL C N   1 
ATOM 2587 C CA  . VAL C 1 27  ? -11.204 32.986  148.309 1.00 14.33  ? 27  VAL C CA  1 
ATOM 2588 C C   . VAL C 1 27  ? -9.841  33.608  148.027 1.00 14.33  ? 27  VAL C C   1 
ATOM 2589 O O   . VAL C 1 27  ? -9.573  34.060  146.908 1.00 14.33  ? 27  VAL C O   1 
ATOM 2590 C CB  . VAL C 1 27  ? -12.180 34.024  148.898 1.00 14.33  ? 27  VAL C CB  1 
ATOM 2591 C CG1 . VAL C 1 27  ? -12.311 35.235  147.978 1.00 14.33  ? 27  VAL C CG1 1 
ATOM 2592 C CG2 . VAL C 1 27  ? -13.544 33.404  149.143 1.00 14.33  ? 27  VAL C CG2 1 
ATOM 2593 N N   . ARG C 1 28  ? -8.958  33.644  149.027 1.00 15.69  ? 28  ARG C N   1 
ATOM 2594 C CA  . ARG C 1 28  ? -7.620  34.190  148.807 1.00 15.69  ? 28  ARG C CA  1 
ATOM 2595 C C   . ARG C 1 28  ? -6.847  33.391  147.763 1.00 15.69  ? 28  ARG C C   1 
ATOM 2596 O O   . ARG C 1 28  ? -6.248  33.962  146.843 1.00 15.69  ? 28  ARG C O   1 
ATOM 2597 C CB  . ARG C 1 28  ? -6.857  34.230  150.133 1.00 15.69  ? 28  ARG C CB  1 
ATOM 2598 C CG  . ARG C 1 28  ? -7.417  35.214  151.154 1.00 15.69  ? 28  ARG C CG  1 
ATOM 2599 C CD  . ARG C 1 28  ? -6.575  35.228  152.421 1.00 15.69  ? 28  ARG C CD  1 
ATOM 2600 N NE  . ARG C 1 28  ? -7.132  36.109  153.438 1.00 15.69  ? 28  ARG C NE  1 
ATOM 2601 C CZ  . ARG C 1 28  ? -6.663  36.222  154.673 1.00 15.69  ? 28  ARG C CZ  1 
ATOM 2602 N NH1 . ARG C 1 28  ? -5.633  35.502  155.089 1.00 15.69  ? 28  ARG C NH1 1 
ATOM 2603 N NH2 . ARG C 1 28  ? -7.245  37.072  155.514 1.00 15.69  ? 28  ARG C NH2 1 
ATOM 2604 N N   . ASP C 1 29  ? -6.859  32.062  147.881 1.00 14.44  ? 29  ASP C N   1 
ATOM 2605 C CA  . ASP C 1 29  ? -6.135  31.221  146.935 1.00 14.44  ? 29  ASP C CA  1 
ATOM 2606 C C   . ASP C 1 29  ? -6.703  31.335  145.527 1.00 14.44  ? 29  ASP C C   1 
ATOM 2607 O O   . ASP C 1 29  ? -5.952  31.432  144.549 1.00 14.44  ? 29  ASP C O   1 
ATOM 2608 C CB  . ASP C 1 29  ? -6.171  29.766  147.405 1.00 14.44  ? 29  ASP C CB  1 
ATOM 2609 C CG  . ASP C 1 29  ? -5.258  29.514  148.589 1.00 14.44  ? 29  ASP C CG  1 
ATOM 2610 O OD1 . ASP C 1 29  ? -4.390  30.368  148.856 1.00 14.44  ? 29  ASP C OD1 1 
ATOM 2611 O OD2 . ASP C 1 29  ? -5.387  28.450  149.234 1.00 14.44  ? 29  ASP C OD2 1 
ATOM 2612 N N   . LEU C 1 30  ? -8.029  31.376  145.409 1.00 12.95  ? 30  LEU C N   1 
ATOM 2613 C CA  . LEU C 1 30  ? -8.656  31.495  144.097 1.00 12.95  ? 30  LEU C CA  1 
ATOM 2614 C C   . LEU C 1 30  ? -8.385  32.853  143.464 1.00 12.95  ? 30  LEU C C   1 
ATOM 2615 O O   . LEU C 1 30  ? -8.098  32.933  142.266 1.00 12.95  ? 30  LEU C O   1 
ATOM 2616 C CB  . LEU C 1 30  ? -10.161 31.251  144.215 1.00 12.95  ? 30  LEU C CB  1 
ATOM 2617 C CG  . LEU C 1 30  ? -10.557 29.831  144.622 1.00 12.95  ? 30  LEU C CG  1 
ATOM 2618 C CD1 . LEU C 1 30  ? -12.016 29.782  145.025 1.00 12.95  ? 30  LEU C CD1 1 
ATOM 2619 C CD2 . LEU C 1 30  ? -10.280 28.848  143.496 1.00 12.95  ? 30  LEU C CD2 1 
ATOM 2620 N N   . LEU C 1 31  ? -8.482  33.933  144.238 1.00 13.85  ? 31  LEU C N   1 
ATOM 2621 C CA  . LEU C 1 31  ? -8.192  35.252  143.685 1.00 13.85  ? 31  LEU C CA  1 
ATOM 2622 C C   . LEU C 1 31  ? -6.725  35.403  143.297 1.00 13.85  ? 31  LEU C C   1 
ATOM 2623 O O   . LEU C 1 31  ? -6.420  35.988  142.250 1.00 13.85  ? 31  LEU C O   1 
ATOM 2624 C CB  . LEU C 1 31  ? -8.586  36.338  144.686 1.00 13.85  ? 31  LEU C CB  1 
ATOM 2625 C CG  . LEU C 1 31  ? -10.084 36.568  144.888 1.00 13.85  ? 31  LEU C CG  1 
ATOM 2626 C CD1 . LEU C 1 31  ? -10.318 37.478  146.079 1.00 13.85  ? 31  LEU C CD1 1 
ATOM 2627 C CD2 . LEU C 1 31  ? -10.718 37.154  143.636 1.00 13.85  ? 31  LEU C CD2 1 
ATOM 2628 N N   . ASP C 1 32  ? -5.799  34.885  144.108 1.00 14.51  ? 32  ASP C N   1 
ATOM 2629 C CA  . ASP C 1 32  ? -4.393  34.897  143.711 1.00 14.51  ? 32  ASP C CA  1 
ATOM 2630 C C   . ASP C 1 32  ? -4.142  34.082  142.445 1.00 14.51  ? 32  ASP C C   1 
ATOM 2631 O O   . ASP C 1 32  ? -3.407  34.525  141.552 1.00 14.51  ? 32  ASP C O   1 
ATOM 2632 C CB  . ASP C 1 32  ? -3.529  34.369  144.854 1.00 14.51  ? 32  ASP C CB  1 
ATOM 2633 C CG  . ASP C 1 32  ? -3.435  35.345  146.011 1.00 14.51  ? 32  ASP C CG  1 
ATOM 2634 O OD1 . ASP C 1 32  ? -3.871  36.503  145.849 1.00 14.51  ? 32  ASP C OD1 1 
ATOM 2635 O OD2 . ASP C 1 32  ? -2.919  34.955  147.080 1.00 14.51  ? 32  ASP C OD2 1 
ATOM 2636 N N   . THR C 1 33  ? -4.761  32.906  142.330 1.00 13.33  ? 33  THR C N   1 
ATOM 2637 C CA  . THR C 1 33  ? -4.618  32.111  141.114 1.00 13.33  ? 33  THR C CA  1 
ATOM 2638 C C   . THR C 1 33  ? -5.174  32.842  139.899 1.00 13.33  ? 33  THR C C   1 
ATOM 2639 O O   . THR C 1 33  ? -4.544  32.873  138.834 1.00 13.33  ? 33  THR C O   1 
ATOM 2640 C CB  . THR C 1 33  ? -5.318  30.761  141.289 1.00 13.33  ? 33  THR C CB  1 
ATOM 2641 O OG1 . THR C 1 33  ? -4.768  30.078  142.422 1.00 13.33  ? 33  THR C OG1 1 
ATOM 2642 C CG2 . THR C 1 33  ? -5.147  29.898  140.046 1.00 13.33  ? 33  THR C CG2 1 
ATOM 2643 N N   . ALA C 1 34  ? -6.367  33.417  140.034 1.00 13.22  ? 34  ALA C N   1 
ATOM 2644 C CA  . ALA C 1 34  ? -6.974  34.144  138.927 1.00 13.22  ? 34  ALA C CA  1 
ATOM 2645 C C   . ALA C 1 34  ? -6.141  35.347  138.513 1.00 13.22  ? 34  ALA C C   1 
ATOM 2646 O O   . ALA C 1 34  ? -5.912  35.563  137.321 1.00 13.22  ? 34  ALA C O   1 
ATOM 2647 C CB  . ALA C 1 34  ? -8.388  34.586  139.304 1.00 13.22  ? 34  ALA C CB  1 
ATOM 2648 N N   . SER C 1 35  ? -5.615  36.100  139.477 1.00 14.43  ? 35  SER C N   1 
ATOM 2649 C CA  . SER C 1 35  ? -4.748  37.221  139.131 1.00 14.43  ? 35  SER C CA  1 
ATOM 2650 C C   . SER C 1 35  ? -3.489  36.757  138.409 1.00 14.43  ? 35  SER C C   1 
ATOM 2651 O O   . SER C 1 35  ? -3.243  37.173  137.273 1.00 14.43  ? 35  SER C O   1 
ATOM 2652 C CB  . SER C 1 35  ? -4.385  38.005  140.390 1.00 14.43  ? 35  SER C CB  1 
ATOM 2653 O OG  . SER C 1 35  ? -3.518  39.084  140.084 1.00 14.43  ? 35  SER C OG  1 
ATOM 2654 N N   . ALA C 1 36  ? -2.814  35.744  138.951 1.00 13.57  ? 36  ALA C N   1 
ATOM 2655 C CA  . ALA C 1 36  ? -1.562  35.280  138.362 1.00 13.57  ? 36  ALA C CA  1 
ATOM 2656 C C   . ALA C 1 36  ? -1.758  34.733  136.953 1.00 13.57  ? 36  ALA C C   1 
ATOM 2657 O O   . ALA C 1 36  ? -1.014  35.091  136.033 1.00 13.57  ? 36  ALA C O   1 
ATOM 2658 C CB  . ALA C 1 36  ? -0.929  34.216  139.261 1.00 13.57  ? 36  ALA C CB  1 
ATOM 2659 N N   . LEU C 1 37  ? -2.746  33.865  136.757 1.00 13.77  ? 37  LEU C N   1 
ATOM 2660 C CA  . LEU C 1 37  ? -2.953  33.291  135.430 1.00 13.77  ? 37  LEU C CA  1 
ATOM 2661 C C   . LEU C 1 37  ? -3.553  34.286  134.438 1.00 13.77  ? 37  LEU C C   1 
ATOM 2662 O O   . LEU C 1 37  ? -3.121  34.336  133.282 1.00 13.77  ? 37  LEU C O   1 
ATOM 2663 C CB  . LEU C 1 37  ? -3.828  32.044  135.536 1.00 13.77  ? 37  LEU C CB  1 
ATOM 2664 C CG  . LEU C 1 37  ? -3.267  30.895  136.378 1.00 13.77  ? 37  LEU C CG  1 
ATOM 2665 C CD1 . LEU C 1 37  ? -4.194  29.693  136.324 1.00 13.77  ? 37  LEU C CD1 1 
ATOM 2666 C CD2 . LEU C 1 37  ? -1.863  30.507  135.927 1.00 13.77  ? 37  LEU C CD2 1 
ATOM 2667 N N   . TYR C 1 38  ? -4.545  35.086  134.846 1.00 13.41  ? 38  TYR C N   1 
ATOM 2668 C CA  . TYR C 1 38  ? -5.456  35.702  133.892 1.00 13.41  ? 38  TYR C CA  1 
ATOM 2669 C C   . TYR C 1 38  ? -5.667  37.204  134.081 1.00 13.41  ? 38  TYR C C   1 
ATOM 2670 O O   . TYR C 1 38  ? -6.558  37.759  133.435 1.00 13.41  ? 38  TYR C O   1 
ATOM 2671 C CB  . TYR C 1 38  ? -6.813  34.987  133.941 1.00 13.41  ? 38  TYR C CB  1 
ATOM 2672 C CG  . TYR C 1 38  ? -6.715  33.495  133.708 1.00 13.41  ? 38  TYR C CG  1 
ATOM 2673 C CD1 . TYR C 1 38  ? -6.232  32.993  132.507 1.00 13.41  ? 38  TYR C CD1 1 
ATOM 2674 C CD2 . TYR C 1 38  ? -7.124  32.588  134.676 1.00 13.41  ? 38  TYR C CD2 1 
ATOM 2675 C CE1 . TYR C 1 38  ? -6.161  31.634  132.275 1.00 13.41  ? 38  TYR C CE1 1 
ATOM 2676 C CE2 . TYR C 1 38  ? -7.047  31.225  134.456 1.00 13.41  ? 38  TYR C CE2 1 
ATOM 2677 C CZ  . TYR C 1 38  ? -6.562  30.754  133.255 1.00 13.41  ? 38  TYR C CZ  1 
ATOM 2678 O OH  . TYR C 1 38  ? -6.459  29.400  133.038 1.00 13.41  ? 38  TYR C OH  1 
ATOM 2679 N N   . ARG C 1 39  ? -4.926  37.874  134.973 1.00 16.36  ? 39  ARG C N   1 
ATOM 2680 C CA  . ARG C 1 39  ? -5.134  39.306  135.183 1.00 16.36  ? 39  ARG C CA  1 
ATOM 2681 C C   . ARG C 1 39  ? -5.122  40.085  133.872 1.00 16.36  ? 39  ARG C C   1 
ATOM 2682 O O   . ARG C 1 39  ? -6.035  40.871  133.594 1.00 16.36  ? 39  ARG C O   1 
ATOM 2683 C CB  . ARG C 1 39  ? -4.065  39.834  136.144 1.00 16.36  ? 39  ARG C CB  1 
ATOM 2684 C CG  . ARG C 1 39  ? -4.173  41.318  136.476 1.00 16.36  ? 39  ARG C CG  1 
ATOM 2685 C CD  . ARG C 1 39  ? -3.121  41.727  137.484 1.00 16.36  ? 39  ARG C CD  1 
ATOM 2686 N NE  . ARG C 1 39  ? -1.774  41.595  136.939 1.00 16.36  ? 39  ARG C NE  1 
ATOM 2687 C CZ  . ARG C 1 39  ? -1.182  42.507  136.180 1.00 16.36  ? 39  ARG C CZ  1 
ATOM 2688 N NH1 . ARG C 1 39  ? -1.787  43.640  135.857 1.00 16.36  ? 39  ARG C NH1 1 
ATOM 2689 N NH2 . ARG C 1 39  ? 0.046   42.277  135.727 1.00 16.36  ? 39  ARG C NH2 1 
ATOM 2690 N N   . GLU C 1 40  ? -4.090  39.884  133.056 1.00 17.69  ? 40  GLU C N   1 
ATOM 2691 C CA  . GLU C 1 40  ? -3.960  40.638  131.811 1.00 17.69  ? 40  GLU C CA  1 
ATOM 2692 C C   . GLU C 1 40  ? -5.133  40.394  130.864 1.00 17.69  ? 40  GLU C C   1 
ATOM 2693 O O   . GLU C 1 40  ? -5.586  41.318  130.178 1.00 17.69  ? 40  GLU C O   1 
ATOM 2694 C CB  . GLU C 1 40  ? -2.636  40.286  131.132 1.00 17.69  ? 40  GLU C CB  1 
ATOM 2695 C CG  . GLU C 1 40  ? -2.369  41.061  129.851 1.00 17.69  ? 40  GLU C CG  1 
ATOM 2696 C CD  . GLU C 1 40  ? -0.990  40.790  129.282 1.00 17.69  ? 40  GLU C CD  1 
ATOM 2697 O OE1 . GLU C 1 40  ? -0.296  39.891  129.803 1.00 17.69  ? 40  GLU C OE1 1 
ATOM 2698 O OE2 . GLU C 1 40  ? -0.598  41.480  128.318 1.00 17.69  ? 40  GLU C OE2 1 
ATOM 2699 N N   . ALA C 1 41  ? -5.636  39.161  130.808 1.00 14.76  ? 41  ALA C N   1 
ATOM 2700 C CA  . ALA C 1 41  ? -6.806  38.855  129.985 1.00 14.76  ? 41  ALA C CA  1 
ATOM 2701 C C   . ALA C 1 41  ? -8.081  39.487  130.538 1.00 14.76  ? 41  ALA C C   1 
ATOM 2702 O O   . ALA C 1 41  ? -8.865  40.080  129.788 1.00 14.76  ? 41  ALA C O   1 
ATOM 2703 C CB  . ALA C 1 41  ? -6.972  37.343  129.862 1.00 14.76  ? 41  ALA C CB  1 
ATOM 2704 N N   . LEU C 1 42  ? -8.312  39.367  131.846 1.00 14.15  ? 42  LEU C N   1 
ATOM 2705 C CA  . LEU C 1 42  ? -9.518  39.931  132.446 1.00 14.15  ? 42  LEU C CA  1 
ATOM 2706 C C   . LEU C 1 42  ? -9.562  41.446  132.286 1.00 14.15  ? 42  LEU C C   1 
ATOM 2707 O O   . LEU C 1 42  ? -10.624 42.016  132.009 1.00 14.15  ? 42  LEU C O   1 
ATOM 2708 C CB  . LEU C 1 42  ? -9.588  39.547  133.924 1.00 14.15  ? 42  LEU C CB  1 
ATOM 2709 C CG  . LEU C 1 42  ? -9.857  38.069  134.219 1.00 14.15  ? 42  LEU C CG  1 
ATOM 2710 C CD1 . LEU C 1 42  ? -9.594  37.764  135.683 1.00 14.15  ? 42  LEU C CD1 1 
ATOM 2711 C CD2 . LEU C 1 42  ? -11.280 37.684  133.845 1.00 14.15  ? 42  LEU C CD2 1 
ATOM 2712 N N   . GLU C 1 43  ? -8.428  42.115  132.463 1.00 16.60  ? 43  GLU C N   1 
ATOM 2713 C CA  . GLU C 1 43  ? -8.344  43.557  132.269 1.00 16.60  ? 43  GLU C CA  1 
ATOM 2714 C C   . GLU C 1 43  ? -8.298  43.962  130.801 1.00 16.60  ? 43  GLU C C   1 
ATOM 2715 O O   . GLU C 1 43  ? -8.315  45.163  130.511 1.00 16.60  ? 43  GLU C O   1 
ATOM 2716 C CB  . GLU C 1 43  ? -7.116  44.119  132.986 1.00 16.60  ? 43  GLU C CB  1 
ATOM 2717 C CG  . GLU C 1 43  ? -7.201  44.057  134.503 1.00 16.60  ? 43  GLU C CG  1 
ATOM 2718 C CD  . GLU C 1 43  ? -5.841  44.135  135.170 1.00 16.60  ? 43  GLU C CD  1 
ATOM 2719 O OE1 . GLU C 1 43  ? -5.789  44.117  136.417 1.00 16.60  ? 43  GLU C OE1 1 
ATOM 2720 O OE2 . GLU C 1 43  ? -4.825  44.214  134.449 1.00 16.60  ? 43  GLU C OE2 1 
ATOM 2721 N N   . SER C 1 44  ? -8.238  43.008  129.872 1.00 15.57  ? 44  SER C N   1 
ATOM 2722 C CA  . SER C 1 44  ? -8.138  43.351  128.464 1.00 15.57  ? 44  SER C CA  1 
ATOM 2723 C C   . SER C 1 44  ? -9.411  44.041  127.965 1.00 15.57  ? 44  SER C C   1 
ATOM 2724 O O   . SER C 1 44  ? -10.480 43.912  128.564 1.00 15.57  ? 44  SER C O   1 
ATOM 2725 C CB  . SER C 1 44  ? -7.870  42.100  127.633 1.00 15.57  ? 44  SER C CB  1 
ATOM 2726 O OG  . SER C 1 44  ? -8.992  41.236  127.634 1.00 15.57  ? 44  SER C OG  1 
ATOM 2727 N N   . PRO C 1 45  ? -9.307  44.795  126.854 1.00 15.54  ? 45  PRO C N   1 
ATOM 2728 C CA  . PRO C 1 45  ? -10.493 45.433  126.258 1.00 15.54  ? 45  PRO C CA  1 
ATOM 2729 C C   . PRO C 1 45  ? -11.445 44.536  125.478 1.00 15.54  ? 45  PRO C C   1 
ATOM 2730 O O   . PRO C 1 45  ? -12.244 45.072  124.705 1.00 15.54  ? 45  PRO C O   1 
ATOM 2731 C CB  . PRO C 1 45  ? -9.880  46.483  125.312 1.00 15.54  ? 45  PRO C CB  1 
ATOM 2732 C CG  . PRO C 1 45  ? -8.477  46.658  125.772 1.00 15.54  ? 45  PRO C CG  1 
ATOM 2733 C CD  . PRO C 1 45  ? -8.079  45.289  126.215 1.00 15.54  ? 45  PRO C CD  1 
ATOM 2734 N N   . GLU C 1 46  ? -11.409 43.214  125.631 1.00 16.94  ? 46  GLU C N   1 
ATOM 2735 C CA  . GLU C 1 46  ? -12.166 42.374  124.711 1.00 16.94  ? 46  GLU C CA  1 
ATOM 2736 C C   . GLU C 1 46  ? -12.741 41.151  125.410 1.00 16.94  ? 46  GLU C C   1 
ATOM 2737 O O   . GLU C 1 46  ? -12.241 40.696  126.442 1.00 16.94  ? 46  GLU C O   1 
ATOM 2738 C CB  . GLU C 1 46  ? -11.288 41.936  123.533 1.00 16.94  ? 46  GLU C CB  1 
ATOM 2739 C CG  . GLU C 1 46  ? -10.134 41.030  123.925 1.00 16.94  ? 46  GLU C CG  1 
ATOM 2740 C CD  . GLU C 1 46  ? -9.221  40.719  122.758 1.00 16.94  ? 46  GLU C CD  1 
ATOM 2741 O OE1 . GLU C 1 46  ? -9.476  41.231  121.649 1.00 16.94  ? 46  GLU C OE1 1 
ATOM 2742 O OE2 . GLU C 1 46  ? -8.244  39.964  122.949 1.00 16.94  ? 46  GLU C OE2 1 
ATOM 2743 N N   . HIS C 1 47  ? -13.816 40.630  124.811 1.00 15.38  ? 47  HIS C N   1 
ATOM 2744 C CA  . HIS C 1 47  ? -14.561 39.473  125.314 1.00 15.38  ? 47  HIS C CA  1 
ATOM 2745 C C   . HIS C 1 47  ? -13.793 38.188  125.001 1.00 15.38  ? 47  HIS C C   1 
ATOM 2746 O O   . HIS C 1 47  ? -14.188 37.372  124.166 1.00 15.38  ? 47  HIS C O   1 
ATOM 2747 C CB  . HIS C 1 47  ? -15.955 39.417  124.704 1.00 15.38  ? 47  HIS C CB  1 
ATOM 2748 C CG  . HIS C 1 47  ? -16.726 40.695  124.813 1.00 15.38  ? 47  HIS C CG  1 
ATOM 2749 N ND1 . HIS C 1 47  ? -16.955 41.518  123.731 1.00 15.38  ? 47  HIS C ND1 1 
ATOM 2750 C CD2 . HIS C 1 47  ? -17.334 41.281  125.869 1.00 15.38  ? 47  HIS C CD2 1 
ATOM 2751 C CE1 . HIS C 1 47  ? -17.667 42.560  124.119 1.00 15.38  ? 47  HIS C CE1 1 
ATOM 2752 N NE2 . HIS C 1 47  ? -17.915 42.439  125.410 1.00 15.38  ? 47  HIS C NE2 1 
ATOM 2753 N N   . CYS C 1 48  ? -12.662 38.017  125.688 1.00 15.02  ? 48  CYS C N   1 
ATOM 2754 C CA  . CYS C 1 48  ? -11.821 36.858  125.416 1.00 15.02  ? 48  CYS C CA  1 
ATOM 2755 C C   . CYS C 1 48  ? -12.627 35.567  125.498 1.00 15.02  ? 48  CYS C C   1 
ATOM 2756 O O   . CYS C 1 48  ? -12.454 34.663  124.673 1.00 15.02  ? 48  CYS C O   1 
ATOM 2757 C CB  . CYS C 1 48  ? -10.650 36.820  126.399 1.00 15.02  ? 48  CYS C CB  1 
ATOM 2758 S SG  . CYS C 1 48  ? -9.623  38.304  126.391 1.00 15.02  ? 48  CYS C SG  1 
ATOM 2759 N N   . SER C 1 49  ? -13.517 35.464  126.484 1.00 13.79  ? 49  SER C N   1 
ATOM 2760 C CA  . SER C 1 49  ? -14.398 34.312  126.615 1.00 13.79  ? 49  SER C CA  1 
ATOM 2761 C C   . SER C 1 49  ? -15.557 34.700  127.519 1.00 13.79  ? 49  SER C C   1 
ATOM 2762 O O   . SER C 1 49  ? -15.409 35.599  128.353 1.00 13.79  ? 49  SER C O   1 
ATOM 2763 C CB  . SER C 1 49  ? -13.655 33.092  127.182 1.00 13.79  ? 49  SER C CB  1 
ATOM 2764 O OG  . SER C 1 49  ? -14.514 31.971  127.286 1.00 13.79  ? 49  SER C OG  1 
ATOM 2765 N N   . PRO C 1 50  ? -16.718 34.058  127.377 1.00 13.01  ? 50  PRO C N   1 
ATOM 2766 C CA  . PRO C 1 50  ? -17.757 34.176  128.413 1.00 13.01  ? 50  PRO C CA  1 
ATOM 2767 C C   . PRO C 1 50  ? -17.292 33.812  129.815 1.00 13.01  ? 50  PRO C C   1 
ATOM 2768 O O   . PRO C 1 50  ? -17.811 34.364  130.793 1.00 13.01  ? 50  PRO C O   1 
ATOM 2769 C CB  . PRO C 1 50  ? -18.858 33.225  127.914 1.00 13.01  ? 50  PRO C CB  1 
ATOM 2770 C CG  . PRO C 1 50  ? -18.170 32.294  126.974 1.00 13.01  ? 50  PRO C CG  1 
ATOM 2771 C CD  . PRO C 1 50  ? -17.135 33.142  126.303 1.00 13.01  ? 50  PRO C CD  1 
ATOM 2772 N N   . HIS C 1 51  ? -16.331 32.894  129.945 1.00 12.31  ? 51  HIS C N   1 
ATOM 2773 C CA  . HIS C 1 51  ? -15.687 32.662  131.235 1.00 12.31  ? 51  HIS C CA  1 
ATOM 2774 C C   . HIS C 1 51  ? -15.043 33.929  131.796 1.00 12.31  ? 51  HIS C C   1 
ATOM 2775 O O   . HIS C 1 51  ? -15.202 34.239  132.985 1.00 12.31  ? 51  HIS C O   1 
ATOM 2776 C CB  . HIS C 1 51  ? -14.628 31.568  131.090 1.00 12.31  ? 51  HIS C CB  1 
ATOM 2777 C CG  . HIS C 1 51  ? -15.191 30.211  130.797 1.00 12.31  ? 51  HIS C CG  1 
ATOM 2778 N ND1 . HIS C 1 51  ? -15.984 29.523  131.689 1.00 12.31  ? 51  HIS C ND1 1 
ATOM 2779 C CD2 . HIS C 1 51  ? -15.080 29.419  129.706 1.00 12.31  ? 51  HIS C CD2 1 
ATOM 2780 C CE1 . HIS C 1 51  ? -16.339 28.367  131.160 1.00 12.31  ? 51  HIS C CE1 1 
ATOM 2781 N NE2 . HIS C 1 51  ? -15.799 28.275  129.959 1.00 12.31  ? 51  HIS C NE2 1 
ATOM 2782 N N   . HIS C 1 52  ? -14.333 34.688  130.957 1.00 12.72  ? 52  HIS C N   1 
ATOM 2783 C CA  . HIS C 1 52  ? -13.755 35.950  131.412 1.00 12.72  ? 52  HIS C CA  1 
ATOM 2784 C C   . HIS C 1 52  ? -14.818 36.967  131.809 1.00 12.72  ? 52  HIS C C   1 
ATOM 2785 O O   . HIS C 1 52  ? -14.663 37.668  132.811 1.00 12.72  ? 52  HIS C O   1 
ATOM 2786 C CB  . HIS C 1 52  ? -12.845 36.545  130.335 1.00 12.72  ? 52  HIS C CB  1 
ATOM 2787 C CG  . HIS C 1 52  ? -11.665 35.692  129.986 1.00 12.72  ? 52  HIS C CG  1 
ATOM 2788 N ND1 . HIS C 1 52  ? -11.723 34.691  129.042 1.00 12.72  ? 52  HIS C ND1 1 
ATOM 2789 C CD2 . HIS C 1 52  ? -10.393 35.696  130.450 1.00 12.72  ? 52  HIS C CD2 1 
ATOM 2790 C CE1 . HIS C 1 52  ? -10.543 34.111  128.942 1.00 12.72  ? 52  HIS C CE1 1 
ATOM 2791 N NE2 . HIS C 1 52  ? -9.716  34.701  129.786 1.00 12.72  ? 52  HIS C NE2 1 
ATOM 2792 N N   . THR C 1 53  ? -15.901 37.073  131.043 1.00 12.97  ? 53  THR C N   1 
ATOM 2793 C CA  . THR C 1 53  ? -16.996 38.033  131.332 1.00 12.97  ? 53  THR C CA  1 
ATOM 2794 C C   . THR C 1 53  ? -17.576 37.709  132.704 1.00 12.97  ? 53  THR C C   1 
ATOM 2795 O O   . THR C 1 53  ? -17.648 38.629  133.583 1.00 12.97  ? 53  THR C O   1 
ATOM 2796 C CB  . THR C 1 53  ? -18.069 37.978  130.248 1.00 12.97  ? 53  THR C CB  1 
ATOM 2797 O OG1 . THR C 1 53  ? -17.472 38.403  129.024 1.00 12.97  ? 53  THR C OG1 1 
ATOM 2798 C CG2 . THR C 1 53  ? -19.267 38.845  130.563 1.00 12.97  ? 53  THR C CG2 1 
ATOM 2799 N N   . ALA C 1 54  ? -17.957 36.455  132.910 1.00 12.77  ? 54  ALA C N   1 
ATOM 2800 C CA  . ALA C 1 54  ? -18.524 36.005  134.192 1.00 12.77  ? 54  ALA C CA  1 
ATOM 2801 C C   . ALA C 1 54  ? -17.531 36.306  135.304 1.00 12.77  ? 54  ALA C C   1 
ATOM 2802 O O   . ALA C 1 54  ? -17.930 36.942  136.294 1.00 12.77  ? 54  ALA C O   1 
ATOM 2803 C CB  . ALA C 1 54  ? -18.816 34.543  134.104 1.00 12.77  ? 54  ALA C CB  1 
ATOM 2804 N N   . LEU C 1 55  ? -16.277 35.903  135.134 1.00 12.90  ? 55  LEU C N   1 
ATOM 2805 C CA  . LEU C 1 55  ? -15.242 36.110  136.170 1.00 12.90  ? 55  LEU C CA  1 
ATOM 2806 C C   . LEU C 1 55  ? -15.157 37.601  136.476 1.00 12.90  ? 55  LEU C C   1 
ATOM 2807 O O   . LEU C 1 55  ? -15.186 37.939  137.650 1.00 12.90  ? 55  LEU C O   1 
ATOM 2808 C CB  . LEU C 1 55  ? -13.909 35.554  135.673 1.00 12.90  ? 55  LEU C CB  1 
ATOM 2809 C CG  . LEU C 1 55  ? -13.738 34.046  135.824 1.00 12.90  ? 55  LEU C CG  1 
ATOM 2810 C CD1 . LEU C 1 55  ? -12.507 33.561  135.078 1.00 12.90  ? 55  LEU C CD1 1 
ATOM 2811 C CD2 . LEU C 1 55  ? -13.661 33.656  137.289 1.00 12.90  ? 55  LEU C CD2 1 
ATOM 2812 N N   . ARG C 1 56  ? -15.099 38.460  135.462 1.00 13.47  ? 56  ARG C N   1 
ATOM 2813 C CA  . ARG C 1 56  ? -15.009 39.926  135.651 1.00 13.47  ? 56  ARG C CA  1 
ATOM 2814 C C   . ARG C 1 56  ? -16.158 40.379  136.548 1.00 13.47  ? 56  ARG C C   1 
ATOM 2815 O O   . ARG C 1 56  ? -15.893 40.973  137.640 1.00 13.47  ? 56  ARG C O   1 
ATOM 2816 C CB  . ARG C 1 56  ? -15.073 40.638  134.300 1.00 13.47  ? 56  ARG C CB  1 
ATOM 2817 C CG  . ARG C 1 56  ? -13.794 40.558  133.484 1.00 13.47  ? 56  ARG C CG  1 
ATOM 2818 C CD  . ARG C 1 56  ? -14.085 40.637  132.000 1.00 13.47  ? 56  ARG C CD  1 
ATOM 2819 N NE  . ARG C 1 56  ? -12.861 40.691  131.217 1.00 13.47  ? 56  ARG C NE  1 
ATOM 2820 C CZ  . ARG C 1 56  ? -12.728 40.240  129.976 1.00 13.47  ? 56  ARG C CZ  1 
ATOM 2821 N NH1 . ARG C 1 56  ? -13.741 39.668  129.352 1.00 13.47  ? 56  ARG C NH1 1 
ATOM 2822 N NH2 . ARG C 1 56  ? -11.564 40.346  129.365 1.00 13.47  ? 56  ARG C NH2 1 
ATOM 2823 N N   . GLN C 1 57  ? -17.390 40.072  136.153 1.00 13.38  ? 57  GLN C N   1 
ATOM 2824 C CA  . GLN C 1 57  ? -18.570 40.522  136.932 1.00 13.38  ? 57  GLN C CA  1 
ATOM 2825 C C   . GLN C 1 57  ? -18.433 40.034  138.372 1.00 13.38  ? 57  GLN C C   1 
ATOM 2826 O O   . GLN C 1 57  ? -18.562 40.867  139.293 1.00 13.38  ? 57  GLN C O   1 
ATOM 2827 C CB  . GLN C 1 57  ? -19.856 39.999  136.299 1.00 13.38  ? 57  GLN C CB  1 
ATOM 2828 C CG  . GLN C 1 57  ? -20.139 40.583  134.927 1.00 13.38  ? 57  GLN C CG  1 
ATOM 2829 C CD  . GLN C 1 57  ? -20.278 42.083  134.971 1.00 13.38  ? 57  GLN C CD  1 
ATOM 2830 O OE1 . GLN C 1 57  ? -20.868 42.642  135.891 1.00 13.38  ? 57  GLN C OE1 1 
ATOM 2831 N NE2 . GLN C 1 57  ? -19.736 42.750  133.967 1.00 13.38  ? 57  GLN C NE2 1 
ATOM 2832 N N   . ALA C 1 58  ? -18.118 38.761  138.579 1.00 13.63  ? 58  ALA C N   1 
ATOM 2833 C CA  . ALA C 1 58  ? -18.034 38.161  139.928 1.00 13.63  ? 58  ALA C CA  1 
ATOM 2834 C C   . ALA C 1 58  ? -16.987 38.870  140.779 1.00 13.63  ? 58  ALA C C   1 
ATOM 2835 O O   . ALA C 1 58  ? -17.271 39.140  141.956 1.00 13.63  ? 58  ALA C O   1 
ATOM 2836 C CB  . ALA C 1 58  ? -17.702 36.711  139.782 1.00 13.63  ? 58  ALA C CB  1 
ATOM 2837 N N   . ILE C 1 59  ? -15.812 39.135  140.227 1.00 13.97  ? 59  ILE C N   1 
ATOM 2838 C CA  . ILE C 1 59  ? -14.707 39.796  140.969 1.00 13.97  ? 59  ILE C CA  1 
ATOM 2839 C C   . ILE C 1 59  ? -15.181 41.192  141.365 1.00 13.97  ? 59  ILE C C   1 
ATOM 2840 O O   . ILE C 1 59  ? -15.032 41.552  142.547 1.00 13.97  ? 59  ILE C O   1 
ATOM 2841 C CB  . ILE C 1 59  ? -13.428 39.813  140.120 1.00 13.97  ? 59  ILE C CB  1 
ATOM 2842 C CG1 . ILE C 1 59  ? -12.909 38.395  139.877 1.00 13.97  ? 59  ILE C CG1 1 
ATOM 2843 C CG2 . ILE C 1 59  ? -12.370 40.697  140.752 1.00 13.97  ? 59  ILE C CG2 1 
ATOM 2844 C CD1 . ILE C 1 59  ? -11.925 38.292  138.744 1.00 13.97  ? 59  ILE C CD1 1 
ATOM 2845 N N   . LEU C 1 60  ? -15.790 41.929  140.440 1.00 14.28  ? 60  LEU C N   1 
ATOM 2846 C CA  . LEU C 1 60  ? -16.307 43.284  140.758 1.00 14.28  ? 60  LEU C CA  1 
ATOM 2847 C C   . LEU C 1 60  ? -17.292 43.170  141.927 1.00 14.28  ? 60  LEU C C   1 
ATOM 2848 O O   . LEU C 1 60  ? -17.193 43.983  142.897 1.00 14.28  ? 60  LEU C O   1 
ATOM 2849 C CB  . LEU C 1 60  ? -16.972 43.863  139.510 1.00 14.28  ? 60  LEU C CB  1 
ATOM 2850 C CG  . LEU C 1 60  ? -16.024 44.258  138.381 1.00 14.28  ? 60  LEU C CG  1 
ATOM 2851 C CD1 . LEU C 1 60  ? -16.788 44.572  137.107 1.00 14.28  ? 60  LEU C CD1 1 
ATOM 2852 C CD2 . LEU C 1 60  ? -15.174 45.443  138.793 1.00 14.28  ? 60  LEU C CD2 1 
ATOM 2853 N N   . CYS C 1 61  ? -18.178 42.181  141.891 1.00 15.63  ? 61  CYS C N   1 
ATOM 2854 C CA  . CYS C 1 61  ? -19.202 41.973  142.949 1.00 15.63  ? 61  CYS C CA  1 
ATOM 2855 C C   . CYS C 1 61  ? -18.554 41.686  144.304 1.00 15.63  ? 61  CYS C C   1 
ATOM 2856 O O   . CYS C 1 61  ? -19.010 42.263  145.314 1.00 15.63  ? 61  CYS C O   1 
ATOM 2857 C CB  . CYS C 1 61  ? -20.116 40.815  142.586 1.00 15.63  ? 61  CYS C CB  1 
ATOM 2858 S SG  . CYS C 1 61  ? -21.532 40.646  143.702 1.00 15.63  ? 61  CYS C SG  1 
ATOM 2859 N N   . TRP C 1 62  ? -17.551 40.811  144.347 1.00 16.21  ? 62  TRP C N   1 
ATOM 2860 C CA  . TRP C 1 62  ? -16.869 40.471  145.617 1.00 16.21  ? 62  TRP C CA  1 
ATOM 2861 C C   . TRP C 1 62  ? -16.204 41.735  146.132 1.00 16.21  ? 62  TRP C C   1 
ATOM 2862 O O   . TRP C 1 62  ? -16.222 41.947  147.342 1.00 16.21  ? 62  TRP C O   1 
ATOM 2863 C CB  . TRP C 1 62  ? -15.852 39.348  145.451 1.00 16.21  ? 62  TRP C CB  1 
ATOM 2864 C CG  . TRP C 1 62  ? -15.263 38.894  146.749 1.00 16.21  ? 62  TRP C CG  1 
ATOM 2865 C CD1 . TRP C 1 62  ? -13.992 39.099  147.195 1.00 16.21  ? 62  TRP C CD1 1 
ATOM 2866 C CD2 . TRP C 1 62  ? -15.939 38.167  147.788 1.00 16.21  ? 62  TRP C CD2 1 
ATOM 2867 N NE1 . TRP C 1 62  ? -13.826 38.542  148.432 1.00 16.21  ? 62  TRP C NE1 1 
ATOM 2868 C CE2 . TRP C 1 62  ? -15.004 37.964  148.822 1.00 16.21  ? 62  TRP C CE2 1 
ATOM 2869 C CE3 . TRP C 1 62  ? -17.235 37.667  147.941 1.00 16.21  ? 62  TRP C CE3 1 
ATOM 2870 C CZ2 . TRP C 1 62  ? -15.330 37.282  149.992 1.00 16.21  ? 62  TRP C CZ2 1 
ATOM 2871 C CZ3 . TRP C 1 62  ? -17.556 36.992  149.097 1.00 16.21  ? 62  TRP C CZ3 1 
ATOM 2872 C CH2 . TRP C 1 62  ? -16.614 36.805  150.106 1.00 16.21  ? 62  TRP C CH2 1 
ATOM 2873 N N   . GLY C 1 63  ? -15.627 42.532  145.246 1.00 16.83  ? 63  GLY C N   1 
ATOM 2874 C CA  . GLY C 1 63  ? -15.011 43.806  145.647 1.00 16.83  ? 63  GLY C CA  1 
ATOM 2875 C C   . GLY C 1 63  ? -16.032 44.672  146.344 1.00 16.83  ? 63  GLY C C   1 
ATOM 2876 O O   . GLY C 1 63  ? -15.750 45.157  147.460 1.00 16.83  ? 63  GLY C O   1 
ATOM 2877 N N   . GLU C 1 64  ? -17.202 44.829  145.734 1.00 18.36  ? 64  GLU C N   1 
ATOM 2878 C CA  . GLU C 1 64  ? -18.285 45.642  146.336 1.00 18.36  ? 64  GLU C CA  1 
ATOM 2879 C C   . GLU C 1 64  ? -18.659 45.077  147.706 1.00 18.36  ? 64  GLU C C   1 
ATOM 2880 O O   . GLU C 1 64  ? -18.838 45.877  148.634 1.00 18.36  ? 64  GLU C O   1 
ATOM 2881 C CB  . GLU C 1 64  ? -19.496 45.665  145.413 1.00 18.36  ? 64  GLU C CB  1 
ATOM 2882 C CG  . GLU C 1 64  ? -19.280 46.495  144.165 1.00 18.36  ? 64  GLU C CG  1 
ATOM 2883 C CD  . GLU C 1 64  ? -19.003 47.962  144.435 1.00 18.36  ? 64  GLU C CD  1 
ATOM 2884 O OE1 . GLU C 1 64  ? -18.463 48.636  143.538 1.00 18.36  ? 64  GLU C OE1 1 
ATOM 2885 O OE2 . GLU C 1 64  ? -19.333 48.428  145.541 1.00 18.36  ? 64  GLU C OE2 1 
ATOM 2886 N N   . LEU C 1 65  ? -18.778 43.759  147.837 1.00 20.26  ? 65  LEU C N   1 
ATOM 2887 C CA  . LEU C 1 65  ? -19.172 43.122  149.121 1.00 20.26  ? 65  LEU C CA  1 
ATOM 2888 C C   . LEU C 1 65  ? -18.113 43.401  150.187 1.00 20.26  ? 65  LEU C C   1 
ATOM 2889 O O   . LEU C 1 65  ? -18.493 43.651  151.339 1.00 20.26  ? 65  LEU C O   1 
ATOM 2890 C CB  . LEU C 1 65  ? -19.347 41.619  148.916 1.00 20.26  ? 65  LEU C CB  1 
ATOM 2891 C CG  . LEU C 1 65  ? -20.641 41.196  148.229 1.00 20.26  ? 65  LEU C CG  1 
ATOM 2892 C CD1 . LEU C 1 65  ? -20.623 39.707  147.932 1.00 20.26  ? 65  LEU C CD1 1 
ATOM 2893 C CD2 . LEU C 1 65  ? -21.846 41.554  149.078 1.00 20.26  ? 65  LEU C CD2 1 
ATOM 2894 N N   . MET C 1 66  ? -16.836 43.343  149.835 1.00 20.74  ? 66  MET C N   1 
ATOM 2895 C CA  . MET C 1 66  ? -15.734 43.605  150.791 1.00 20.74  ? 66  MET C CA  1 
ATOM 2896 C C   . MET C 1 66  ? -15.783 45.077  151.196 1.00 20.74  ? 66  MET C C   1 
ATOM 2897 O O   . MET C 1 66  ? -15.517 45.389  152.387 1.00 20.74  ? 66  MET C O   1 
ATOM 2898 C CB  . MET C 1 66  ? -14.381 43.273  150.164 1.00 20.74  ? 66  MET C CB  1 
ATOM 2899 C CG  . MET C 1 66  ? -14.190 41.799  149.876 1.00 20.74  ? 66  MET C CG  1 
ATOM 2900 S SD  . MET C 1 66  ? -14.612 40.742  151.280 1.00 20.74  ? 66  MET C SD  1 
ATOM 2901 C CE  . MET C 1 66  ? -16.331 40.384  150.916 1.00 20.74  ? 66  MET C CE  1 
ATOM 2902 N N   . THR C 1 67  ? -16.110 45.958  150.259 1.00 22.81  ? 67  THR C N   1 
ATOM 2903 C CA  . THR C 1 67  ? -16.271 47.396  150.567 1.00 22.81  ? 67  THR C CA  1 
ATOM 2904 C C   . THR C 1 67  ? -17.388 47.524  151.594 1.00 22.81  ? 67  THR C C   1 
ATOM 2905 O O   . THR C 1 67  ? -17.187 48.245  152.567 1.00 22.81  ? 67  THR C O   1 
ATOM 2906 C CB  . THR C 1 67  ? -16.574 48.217  149.315 1.00 22.81  ? 67  THR C CB  1 
ATOM 2907 O OG1 . THR C 1 67  ? -15.395 48.238  148.513 1.00 22.81  ? 67  THR C OG1 1 
ATOM 2908 C CG2 . THR C 1 67  ? -17.007 49.630  149.630 1.00 22.81  ? 67  THR C CG2 1 
ATOM 2909 N N   . LEU C 1 68  ? -18.503 46.827  151.389 1.00 25.34  ? 68  LEU C N   1 
ATOM 2910 C CA  . LEU C 1 68  ? -19.649 46.868  152.332 1.00 25.34  ? 68  LEU C CA  1 
ATOM 2911 C C   . LEU C 1 68  ? -19.166 46.405  153.692 1.00 25.34  ? 68  LEU C C   1 
ATOM 2912 O O   . LEU C 1 68  ? -19.549 47.022  154.681 1.00 25.34  ? 68  LEU C O   1 
ATOM 2913 C CB  . LEU C 1 68  ? -20.775 45.955  151.853 1.00 25.34  ? 68  LEU C CB  1 
ATOM 2914 C CG  . LEU C 1 68  ? -21.833 45.614  152.899 1.00 25.34  ? 68  LEU C CG  1 
ATOM 2915 C CD1 . LEU C 1 68  ? -22.447 46.874  153.482 1.00 25.34  ? 68  LEU C CD1 1 
ATOM 2916 C CD2 . LEU C 1 68  ? -22.913 44.731  152.304 1.00 25.34  ? 68  LEU C CD2 1 
ATOM 2917 N N   . ALA C 1 69  ? -18.384 45.337  153.735 1.00 27.45  ? 69  ALA C N   1 
ATOM 2918 C CA  . ALA C 1 69  ? -17.852 44.794  154.998 1.00 27.45  ? 69  ALA C CA  1 
ATOM 2919 C C   . ALA C 1 69  ? -17.061 45.881  155.717 1.00 27.45  ? 69  ALA C C   1 
ATOM 2920 O O   . ALA C 1 69  ? -17.346 46.124  156.892 1.00 27.45  ? 69  ALA C O   1 
ATOM 2921 C CB  . ALA C 1 69  ? -16.997 43.600  154.714 1.00 27.45  ? 69  ALA C CB  1 
ATOM 2922 N N   . THR C 1 70  ? -16.125 46.532  155.031 1.00 29.43  ? 70  THR C N   1 
ATOM 2923 C CA  . THR C 1 70  ? -15.300 47.605  155.640 1.00 29.43  ? 70  THR C CA  1 
ATOM 2924 C C   . THR C 1 70  ? -16.211 48.717  156.140 1.00 29.43  ? 70  THR C C   1 
ATOM 2925 O O   . THR C 1 70  ? -15.963 49.241  157.250 1.00 29.43  ? 70  THR C O   1 
ATOM 2926 C CB  . THR C 1 70  ? -14.307 48.179  154.632 1.00 29.43  ? 70  THR C CB  1 
ATOM 2927 O OG1 . THR C 1 70  ? -13.361 47.155  154.323 1.00 29.43  ? 70  THR C OG1 1 
ATOM 2928 C CG2 . THR C 1 70  ? -13.594 49.407  155.151 1.00 29.43  ? 70  THR C CG2 1 
ATOM 2929 N N   . TRP C 1 71  ? -17.220 49.076  155.355 1.00 30.73  ? 71  TRP C N   1 
ATOM 2930 C CA  . TRP C 1 71  ? -18.156 50.168  155.708 1.00 30.73  ? 71  TRP C CA  1 
ATOM 2931 C C   . TRP C 1 71  ? -18.852 49.806  157.004 1.00 30.73  ? 71  TRP C C   1 
ATOM 2932 O O   . TRP C 1 71  ? -18.904 50.656  157.847 1.00 30.73  ? 71  TRP C O   1 
ATOM 2933 C CB  . TRP C 1 71  ? -19.174 50.417  154.600 1.00 30.73  ? 71  TRP C CB  1 
ATOM 2934 C CG  . TRP C 1 71  ? -20.263 51.372  154.979 1.00 30.73  ? 71  TRP C CG  1 
ATOM 2935 C CD1 . TRP C 1 71  ? -20.282 52.721  154.786 1.00 30.73  ? 71  TRP C CD1 1 
ATOM 2936 C CD2 . TRP C 1 71  ? -21.504 51.042  155.623 1.00 30.73  ? 71  TRP C CD2 1 
ATOM 2937 N NE1 . TRP C 1 71  ? -21.449 53.253  155.264 1.00 30.73  ? 71  TRP C NE1 1 
ATOM 2938 C CE2 . TRP C 1 71  ? -22.219 52.247  155.783 1.00 30.73  ? 71  TRP C CE2 1 
ATOM 2939 C CE3 . TRP C 1 71  ? -22.080 49.852  156.077 1.00 30.73  ? 71  TRP C CE3 1 
ATOM 2940 C CZ2 . TRP C 1 71  ? -23.476 52.292  156.379 1.00 30.73  ? 71  TRP C CZ2 1 
ATOM 2941 C CZ3 . TRP C 1 71  ? -23.324 49.897  156.665 1.00 30.73  ? 71  TRP C CZ3 1 
ATOM 2942 C CH2 . TRP C 1 71  ? -24.010 51.101  156.812 1.00 30.73  ? 71  TRP C CH2 1 
ATOM 2943 N N   . VAL C 1 72  ? -19.350 48.583  157.138 1.00 33.61  ? 72  VAL C N   1 
ATOM 2944 C CA  . VAL C 1 72  ? -20.020 48.123  158.384 1.00 33.61  ? 72  VAL C CA  1 
ATOM 2945 C C   . VAL C 1 72  ? -18.997 48.246  159.501 1.00 33.61  ? 72  VAL C C   1 
ATOM 2946 O O   . VAL C 1 72  ? -19.272 48.880  160.496 1.00 33.61  ? 72  VAL C O   1 
ATOM 2947 C CB  . VAL C 1 72  ? -20.537 46.682  158.263 1.00 33.61  ? 72  VAL C CB  1 
ATOM 2948 C CG1 . VAL C 1 72  ? -20.875 46.091  159.621 1.00 33.61  ? 72  VAL C CG1 1 
ATOM 2949 C CG2 . VAL C 1 72  ? -21.726 46.597  157.324 1.00 33.61  ? 72  VAL C CG2 1 
ATOM 2950 N N   . GLY C 1 73  ? -17.815 47.695  159.305 1.00 35.64  ? 73  GLY C N   1 
ATOM 2951 C CA  . GLY C 1 73  ? -16.756 47.770  160.320 1.00 35.64  ? 73  GLY C CA  1 
ATOM 2952 C C   . GLY C 1 73  ? -16.585 49.178  160.847 1.00 35.64  ? 73  GLY C C   1 
ATOM 2953 O O   . GLY C 1 73  ? -16.483 49.325  162.079 1.00 35.64  ? 73  GLY C O   1 
ATOM 2954 N N   . VAL C 1 74  ? -16.590 50.187  159.976 1.00 37.08  ? 74  VAL C N   1 
ATOM 2955 C CA  . VAL C 1 74  ? -16.288 51.587  160.399 1.00 37.08  ? 74  VAL C CA  1 
ATOM 2956 C C   . VAL C 1 74  ? -17.526 52.341  160.880 1.00 37.08  ? 74  VAL C C   1 
ATOM 2957 O O   . VAL C 1 74  ? -17.355 53.217  161.738 1.00 37.08  ? 74  VAL C O   1 
ATOM 2958 C CB  . VAL C 1 74  ? -15.643 52.361  159.238 1.00 30.00  ? 74  VAL C CB  1 
ATOM 2959 C CG1 . VAL C 1 74  ? -15.585 53.853  159.511 1.00 30.00  ? 74  VAL C CG1 1 
ATOM 2960 C CG2 . VAL C 1 74  ? -14.265 51.819  158.900 1.00 30.00  ? 74  VAL C CG2 1 
ATOM 2961 N N   . ASN C 1 75  ? -18.719 52.028  160.386 1.00 36.63  ? 75  ASN C N   1 
ATOM 2962 C CA  . ASN C 1 75  ? -19.930 52.838  160.675 1.00 36.63  ? 75  ASN C CA  1 
ATOM 2963 C C   . ASN C 1 75  ? -20.792 52.174  161.738 1.00 36.63  ? 75  ASN C C   1 
ATOM 2964 O O   . ASN C 1 75  ? -21.408 52.909  162.554 1.00 36.63  ? 75  ASN C O   1 
ATOM 2965 C CB  . ASN C 1 75  ? -20.728 53.121  159.407 1.00 36.63  ? 75  ASN C CB  1 
ATOM 2966 C CG  . ASN C 1 75  ? -19.968 53.966  158.410 1.00 36.63  ? 75  ASN C CG  1 
ATOM 2967 O OD1 . ASN C 1 75  ? -19.912 53.640  157.227 1.00 36.63  ? 75  ASN C OD1 1 
ATOM 2968 N ND2 . ASN C 1 75  ? -19.377 55.053  158.874 1.00 36.63  ? 75  ASN C ND2 1 
ATOM 2969 N N   . LEU C 1 76  ? -20.886 50.843  161.715 1.00 40.21  ? 76  LEU C N   1 
ATOM 2970 C CA  . LEU C 1 76  ? -21.721 50.087  162.681 1.00 40.21  ? 76  LEU C CA  1 
ATOM 2971 C C   . LEU C 1 76  ? -21.056 50.157  164.057 1.00 40.21  ? 76  LEU C C   1 
ATOM 2972 O O   . LEU C 1 76  ? -19.959 49.607  164.195 1.00 40.21  ? 76  LEU C O   1 
ATOM 2973 C CB  . LEU C 1 76  ? -21.876 48.643  162.194 1.00 40.21  ? 76  LEU C CB  1 
ATOM 2974 C CG  . LEU C 1 76  ? -22.773 47.747  163.045 1.00 40.21  ? 76  LEU C CG  1 
ATOM 2975 C CD1 . LEU C 1 76  ? -23.994 48.501  163.549 1.00 40.21  ? 76  LEU C CD1 1 
ATOM 2976 C CD2 . LEU C 1 76  ? -23.201 46.518  162.264 1.00 40.21  ? 76  LEU C CD2 1 
ATOM 2977 N N   . GLU C 1 77  ? -21.657 50.870  165.011 1.00 45.13  ? 77  GLU C N   1 
ATOM 2978 C CA  . GLU C 1 77  ? -21.142 50.965  166.404 1.00 45.13  ? 77  GLU C CA  1 
ATOM 2979 C C   . GLU C 1 77  ? -21.419 49.651  167.138 1.00 45.13  ? 77  GLU C C   1 
ATOM 2980 O O   . GLU C 1 77  ? -20.632 49.317  168.045 1.00 45.13  ? 77  GLU C O   1 
ATOM 2981 C CB  . GLU C 1 77  ? -21.802 52.139  167.131 1.00 45.13  ? 77  GLU C CB  1 
ATOM 2982 C CG  . GLU C 1 77  ? -23.269 51.912  167.461 1.00 45.13  ? 77  GLU C CG  1 
ATOM 2983 C CD  . GLU C 1 77  ? -24.238 52.115  166.308 1.00 45.13  ? 77  GLU C CD  1 
ATOM 2984 O OE1 . GLU C 1 77  ? -23.771 52.351  165.177 1.00 45.13  ? 77  GLU C OE1 1 
ATOM 2985 O OE2 . GLU C 1 77  ? -25.459 52.029  166.545 1.00 45.13  ? 77  GLU C OE2 1 
ATOM 2986 N N   . ASP C 1 78  ? -22.483 48.936  166.769 1.00 44.19  ? 78  ASP C N   1 
ATOM 2987 C CA  . ASP C 1 78  ? -22.884 47.672  167.442 1.00 44.19  ? 78  ASP C CA  1 
ATOM 2988 C C   . ASP C 1 78  ? -21.938 46.551  166.998 1.00 44.19  ? 78  ASP C C   1 
ATOM 2989 O O   . ASP C 1 78  ? -21.939 46.222  165.799 1.00 44.19  ? 78  ASP C O   1 
ATOM 2990 C CB  . ASP C 1 78  ? -24.351 47.357  167.147 1.00 44.19  ? 78  ASP C CB  1 
ATOM 2991 C CG  . ASP C 1 78  ? -24.905 46.174  167.923 1.00 44.19  ? 78  ASP C CG  1 
ATOM 2992 O OD1 . ASP C 1 78  ? -24.114 45.504  168.616 1.00 44.19  ? 78  ASP C OD1 1 
ATOM 2993 O OD2 . ASP C 1 78  ? -26.124 45.934  167.828 1.00 44.19  ? 78  ASP C OD2 1 
ATOM 2994 N N   . PRO C 1 79  ? -21.134 45.953  167.905 1.00 43.00  ? 79  PRO C N   1 
ATOM 2995 C CA  . PRO C 1 79  ? -20.158 44.923  167.525 1.00 43.00  ? 79  PRO C CA  1 
ATOM 2996 C C   . PRO C 1 79  ? -20.778 43.537  167.302 1.00 43.00  ? 79  PRO C C   1 
ATOM 2997 O O   . PRO C 1 79  ? -20.185 42.773  166.575 1.00 43.00  ? 79  PRO C O   1 
ATOM 2998 C CB  . PRO C 1 79  ? -19.222 44.885  168.740 1.00 43.00  ? 79  PRO C CB  1 
ATOM 2999 C CG  . PRO C 1 79  ? -20.140 45.200  169.895 1.00 43.00  ? 79  PRO C CG  1 
ATOM 3000 C CD  . PRO C 1 79  ? -21.095 46.236  169.342 1.00 43.00  ? 79  PRO C CD  1 
ATOM 3001 N N   . ALA C 1 80  ? -21.837 43.209  168.033 1.00 41.67  ? 80  ALA C N   1 
ATOM 3002 C CA  . ALA C 1 80  ? -22.513 41.905  167.898 1.00 41.67  ? 80  ALA C CA  1 
ATOM 3003 C C   . ALA C 1 80  ? -23.056 41.827  166.480 1.00 41.67  ? 80  ALA C C   1 
ATOM 3004 O O   . ALA C 1 80  ? -22.710 40.874  165.764 1.00 41.67  ? 80  ALA C O   1 
ATOM 3005 C CB  . ALA C 1 80  ? -23.606 41.785  168.919 1.00 41.67  ? 80  ALA C CB  1 
ATOM 3006 N N   . SER C 1 81  ? -23.849 42.816  166.081 1.00 39.98  ? 81  SER C N   1 
ATOM 3007 C CA  . SER C 1 81  ? -24.411 42.880  164.715 1.00 39.98  ? 81  SER C CA  1 
ATOM 3008 C C   . SER C 1 81  ? -23.257 42.995  163.723 1.00 39.98  ? 81  SER C C   1 
ATOM 3009 O O   . SER C 1 81  ? -23.275 42.271  162.718 1.00 39.98  ? 81  SER C O   1 
ATOM 3010 C CB  . SER C 1 81  ? -25.366 44.021  164.595 1.00 39.98  ? 81  SER C CB  1 
ATOM 3011 O OG  . SER C 1 81  ? -24.728 45.242  164.921 1.00 39.98  ? 81  SER C OG  1 
ATOM 3012 N N   . ARG C 1 82  ? -22.273 43.841  164.012 1.00 40.15  ? 82  ARG C N   1 
ATOM 3013 C CA  . ARG C 1 82  ? -21.131 44.057  163.094 1.00 40.15  ? 82  ARG C CA  1 
ATOM 3014 C C   . ARG C 1 82  ? -20.527 42.698  162.765 1.00 40.15  ? 82  ARG C C   1 
ATOM 3015 O O   . ARG C 1 82  ? -20.345 42.404  161.575 1.00 40.15  ? 82  ARG C O   1 
ATOM 3016 C CB  . ARG C 1 82  ? -20.110 44.993  163.734 1.00 40.15  ? 82  ARG C CB  1 
ATOM 3017 C CG  . ARG C 1 82  ? -18.830 45.162  162.934 1.00 40.15  ? 82  ARG C CG  1 
ATOM 3018 C CD  . ARG C 1 82  ? -18.239 46.538  163.145 1.00 40.15  ? 82  ARG C CD  1 
ATOM 3019 N NE  . ARG C 1 82  ? -18.515 47.053  164.477 1.00 40.15  ? 82  ARG C NE  1 
ATOM 3020 C CZ  . ARG C 1 82  ? -17.856 46.708  165.576 1.00 40.15  ? 82  ARG C CZ  1 
ATOM 3021 N NH1 . ARG C 1 82  ? -16.875 45.825  165.524 1.00 40.15  ? 82  ARG C NH1 1 
ATOM 3022 N NH2 . ARG C 1 82  ? -18.192 47.245  166.735 1.00 40.15  ? 82  ARG C NH2 1 
ATOM 3023 N N   . ASP C 1 83  ? -20.274 41.878  163.777 1.00 39.02  ? 83  ASP C N   1 
ATOM 3024 C CA  . ASP C 1 83  ? -19.654 40.550  163.575 1.00 39.02  ? 83  ASP C CA  1 
ATOM 3025 C C   . ASP C 1 83  ? -20.635 39.670  162.810 1.00 39.02  ? 83  ASP C C   1 
ATOM 3026 O O   . ASP C 1 83  ? -20.205 39.006  161.856 1.00 39.02  ? 83  ASP C O   1 
ATOM 3027 C CB  . ASP C 1 83  ? -19.265 39.933  164.912 1.00 39.02  ? 83  ASP C CB  1 
ATOM 3028 C CG  . ASP C 1 83  ? -18.238 40.754  165.671 1.00 39.02  ? 83  ASP C CG  1 
ATOM 3029 O OD1 . ASP C 1 83  ? -17.784 41.774  165.117 1.00 39.02  ? 83  ASP C OD1 1 
ATOM 3030 O OD2 . ASP C 1 83  ? -17.907 40.373  166.809 1.00 39.02  ? 83  ASP C OD2 1 
ATOM 3031 N N   . LEU C 1 84  ? -21.906 39.686  163.192 1.00 36.43  ? 84  LEU C N   1 
ATOM 3032 C CA  . LEU C 1 84  ? -22.933 38.825  162.563 1.00 36.43  ? 84  LEU C CA  1 
ATOM 3033 C C   . LEU C 1 84  ? -22.950 39.061  161.057 1.00 36.43  ? 84  LEU C C   1 
ATOM 3034 O O   . LEU C 1 84  ? -22.915 38.071  160.311 1.00 36.43  ? 84  LEU C O   1 
ATOM 3035 C CB  . LEU C 1 84  ? -24.290 39.164  163.178 1.00 36.43  ? 84  LEU C CB  1 
ATOM 3036 C CG  . LEU C 1 84  ? -24.547 38.566  164.557 1.00 36.43  ? 84  LEU C CG  1 
ATOM 3037 C CD1 . LEU C 1 84  ? -25.645 39.326  165.278 1.00 36.43  ? 84  LEU C CD1 1 
ATOM 3038 C CD2 . LEU C 1 84  ? -24.898 37.094  164.440 1.00 36.43  ? 84  LEU C CD2 1 
ATOM 3039 N N   . VAL C 1 85  ? -22.988 40.315  160.616 1.00 34.71  ? 85  VAL C N   1 
ATOM 3040 C CA  . VAL C 1 85  ? -23.110 40.632  159.166 1.00 34.71  ? 85  VAL C CA  1 
ATOM 3041 C C   . VAL C 1 85  ? -21.803 40.270  158.466 1.00 34.71  ? 85  VAL C C   1 
ATOM 3042 O O   . VAL C 1 85  ? -21.870 39.623  157.410 1.00 34.71  ? 85  VAL C O   1 
ATOM 3043 C CB  . VAL C 1 85  ? -23.494 42.104  158.935 1.00 34.71  ? 85  VAL C CB  1 
ATOM 3044 C CG1 . VAL C 1 85  ? -24.890 42.394  159.456 1.00 34.71  ? 85  VAL C CG1 1 
ATOM 3045 C CG2 . VAL C 1 85  ? -22.492 43.069  159.539 1.00 34.71  ? 85  VAL C CG2 1 
ATOM 3046 N N   . VAL C 1 86  ? -20.663 40.638  159.036 1.00 32.53  ? 86  VAL C N   1 
ATOM 3047 C CA  . VAL C 1 86  ? -19.344 40.382  158.397 1.00 32.53  ? 86  VAL C CA  1 
ATOM 3048 C C   . VAL C 1 86  ? -19.197 38.876  158.217 1.00 32.53  ? 86  VAL C C   1 
ATOM 3049 O O   . VAL C 1 86  ? -18.710 38.457  157.159 1.00 32.53  ? 86  VAL C O   1 
ATOM 3050 C CB  . VAL C 1 86  ? -18.193 40.965  159.227 1.00 32.53  ? 86  VAL C CB  1 
ATOM 3051 C CG1 . VAL C 1 86  ? -16.843 40.483  158.730 1.00 32.53  ? 86  VAL C CG1 1 
ATOM 3052 C CG2 . VAL C 1 86  ? -18.245 42.484  159.256 1.00 32.53  ? 86  VAL C CG2 1 
ATOM 3053 N N   . SER C 1 87  ? -19.635 38.088  159.194 1.00 32.33  ? 87  SER C N   1 
ATOM 3054 C CA  . SER C 1 87  ? -19.499 36.614  159.148 1.00 32.33  ? 87  SER C CA  1 
ATOM 3055 C C   . SER C 1 87  ? -20.379 36.050  158.038 1.00 32.33  ? 87  SER C C   1 
ATOM 3056 O O   . SER C 1 87  ? -19.891 35.190  157.298 1.00 32.33  ? 87  SER C O   1 
ATOM 3057 C CB  . SER C 1 87  ? -19.822 35.997  160.471 1.00 30.00  ? 87  SER C CB  1 
ATOM 3058 O OG  . SER C 1 87  ? -21.185 36.186  160.811 1.00 30.00  ? 87  SER C OG  1 
ATOM 3059 N N   . TYR C 1 88  ? -21.613 36.529  157.902 1.00 27.62  ? 88  TYR C N   1 
ATOM 3060 C CA  . TYR C 1 88  ? -22.560 36.026  156.880 1.00 27.62  ? 88  TYR C CA  1 
ATOM 3061 C C   . TYR C 1 88  ? -21.926 36.209  155.511 1.00 27.62  ? 88  TYR C C   1 
ATOM 3062 O O   . TYR C 1 88  ? -21.959 35.268  154.707 1.00 27.62  ? 88  TYR C O   1 
ATOM 3063 C CB  . TYR C 1 88  ? -23.889 36.770  156.940 1.00 27.62  ? 88  TYR C CB  1 
ATOM 3064 C CG  . TYR C 1 88  ? -24.881 36.371  155.881 1.00 27.62  ? 88  TYR C CG  1 
ATOM 3065 C CD1 . TYR C 1 88  ? -24.740 36.804  154.574 1.00 27.62  ? 88  TYR C CD1 1 
ATOM 3066 C CD2 . TYR C 1 88  ? -25.964 35.566  156.184 1.00 27.62  ? 88  TYR C CD2 1 
ATOM 3067 C CE1 . TYR C 1 88  ? -25.649 36.445  153.595 1.00 27.62  ? 88  TYR C CE1 1 
ATOM 3068 C CE2 . TYR C 1 88  ? -26.882 35.199  155.217 1.00 27.62  ? 88  TYR C CE2 1 
ATOM 3069 C CZ  . TYR C 1 88  ? -26.724 35.638  153.917 1.00 27.62  ? 88  TYR C CZ  1 
ATOM 3070 O OH  . TYR C 1 88  ? -27.623 35.278  152.957 1.00 27.62  ? 88  TYR C OH  1 
ATOM 3071 N N   . VAL C 1 89  ? -21.352 37.378  155.236 1.00 25.87  ? 89  VAL C N   1 
ATOM 3072 C CA  . VAL C 1 89  ? -20.746 37.708  153.919 1.00 25.87  ? 89  VAL C CA  1 
ATOM 3073 C C   . VAL C 1 89  ? -19.616 36.739  153.593 1.00 25.87  ? 89  VAL C C   1 
ATOM 3074 O O   . VAL C 1 89  ? -19.614 36.248  152.467 1.00 25.87  ? 89  VAL C O   1 
ATOM 3075 C CB  . VAL C 1 89  ? -20.223 39.150  153.929 1.00 25.87  ? 89  VAL C CB  1 
ATOM 3076 C CG1 . VAL C 1 89  ? -19.336 39.441  152.727 1.00 25.87  ? 89  VAL C CG1 1 
ATOM 3077 C CG2 . VAL C 1 89  ? -21.363 40.151  154.012 1.00 25.87  ? 89  VAL C CG2 1 
ATOM 3078 N N   . ASN C 1 90  ? -18.674 36.503  154.509 1.00 26.73  ? 90  ASN C N   1 
ATOM 3079 C CA  . ASN C 1 90  ? -17.479 35.642  154.271 1.00 26.73  ? 90  ASN C CA  1 
ATOM 3080 C C   . ASN C 1 90  ? -17.818 34.167  154.470 1.00 26.73  ? 90  ASN C C   1 
ATOM 3081 O O   . ASN C 1 90  ? -17.001 33.353  154.049 1.00 26.73  ? 90  ASN C O   1 
ATOM 3082 C CB  . ASN C 1 90  ? -16.299 36.035  155.155 1.00 26.73  ? 90  ASN C CB  1 
ATOM 3083 C CG  . ASN C 1 90  ? -15.871 37.473  154.963 1.00 26.73  ? 90  ASN C CG  1 
ATOM 3084 O OD1 . ASN C 1 90  ? -16.219 38.100  153.966 1.00 26.73  ? 90  ASN C OD1 1 
ATOM 3085 N ND2 . ASN C 1 90  ? -15.120 38.002  155.913 1.00 26.73  ? 90  ASN C ND2 1 
ATOM 3086 N N   . THR C 1 91  ? -18.973 33.778  155.001 1.00 24.78  ? 91  THR C N   1 
ATOM 3087 C CA  . THR C 1 91  ? -19.344 32.333  155.067 1.00 24.78  ? 91  THR C CA  1 
ATOM 3088 C C   . THR C 1 91  ? -20.289 31.976  153.907 1.00 24.78  ? 91  THR C C   1 
ATOM 3089 O O   . THR C 1 91  ? -19.847 31.224  153.048 1.00 24.78  ? 91  THR C O   1 
ATOM 3090 C CB  . THR C 1 91  ? -19.904 31.905  156.432 1.00 24.78  ? 91  THR C CB  1 
ATOM 3091 O OG1 . THR C 1 91  ? -18.882 32.138  157.398 1.00 24.78  ? 91  THR C OG1 1 
ATOM 3092 C CG2 . THR C 1 91  ? -20.317 30.451  156.487 1.00 24.78  ? 91  THR C CG2 1 
ATOM 3093 N N   . ASN C 1 92  ? -21.535 32.456  153.887 1.00 23.90  ? 92  ASN C N   1 
ATOM 3094 C CA  . ASN C 1 92  ? -22.522 32.103  152.828 1.00 23.90  ? 92  ASN C CA  1 
ATOM 3095 C C   . ASN C 1 92  ? -22.101 32.605  151.430 1.00 23.90  ? 92  ASN C C   1 
ATOM 3096 O O   . ASN C 1 92  ? -21.839 31.758  150.497 1.00 23.90  ? 92  ASN C O   1 
ATOM 3097 C CB  . ASN C 1 92  ? -23.900 32.622  153.230 1.00 23.90  ? 92  ASN C CB  1 
ATOM 3098 C CG  . ASN C 1 92  ? -24.503 31.848  154.380 1.00 23.90  ? 92  ASN C CG  1 
ATOM 3099 O OD1 . ASN C 1 92  ? -24.138 30.702  154.620 1.00 23.90  ? 92  ASN C OD1 1 
ATOM 3100 N ND2 . ASN C 1 92  ? -25.420 32.470  155.099 1.00 23.90  ? 92  ASN C ND2 1 
ATOM 3101 N N   . MET C 1 93  ? -22.010 33.916  151.261 1.00 21.82  ? 93  MET C N   1 
ATOM 3102 C CA  . MET C 1 93  ? -21.638 34.503  149.957 1.00 21.82  ? 93  MET C CA  1 
ATOM 3103 C C   . MET C 1 93  ? -20.207 34.067  149.638 1.00 21.82  ? 93  MET C C   1 
ATOM 3104 O O   . MET C 1 93  ? -19.965 33.831  148.482 1.00 21.82  ? 93  MET C O   1 
ATOM 3105 C CB  . MET C 1 93  ? -21.774 36.021  150.005 1.00 21.82  ? 93  MET C CB  1 
ATOM 3106 C CG  . MET C 1 93  ? -23.181 36.488  150.328 1.00 21.82  ? 93  MET C CG  1 
ATOM 3107 S SD  . MET C 1 93  ? -23.264 38.255  150.700 1.00 21.82  ? 93  MET C SD  1 
ATOM 3108 C CE  . MET C 1 93  ? -24.924 38.633  150.145 1.00 21.82  ? 93  MET C CE  1 
ATOM 3109 N N   . GLY C 1 94  ? -19.331 33.902  150.636 1.00 17.83  ? 94  GLY C N   1 
ATOM 3110 C CA  . GLY C 1 94  ? -17.968 33.392  150.418 1.00 17.83  ? 94  GLY C CA  1 
ATOM 3111 C C   . GLY C 1 94  ? -17.988 32.072  149.691 1.00 17.83  ? 94  GLY C C   1 
ATOM 3112 O O   . GLY C 1 94  ? -17.323 32.019  148.681 1.00 17.83  ? 94  GLY C O   1 
ATOM 3113 N N   . LEU C 1 95  ? -18.755 31.079  150.153 1.00 15.93  ? 95  LEU C N   1 
ATOM 3114 C CA  . LEU C 1 95  ? -18.873 29.728  149.538 1.00 15.93  ? 95  LEU C CA  1 
ATOM 3115 C C   . LEU C 1 95  ? -19.586 29.818  148.198 1.00 15.93  ? 95  LEU C C   1 
ATOM 3116 O O   . LEU C 1 95  ? -19.225 29.031  147.316 1.00 15.93  ? 95  LEU C O   1 
ATOM 3117 C CB  . LEU C 1 95  ? -19.649 28.780  150.461 1.00 15.93  ? 95  LEU C CB  1 
ATOM 3118 C CG  . LEU C 1 95  ? -20.031 27.427  149.857 1.00 15.93  ? 95  LEU C CG  1 
ATOM 3119 C CD1 . LEU C 1 95  ? -18.812 26.548  149.645 1.00 15.93  ? 95  LEU C CD1 1 
ATOM 3120 C CD2 . LEU C 1 95  ? -21.045 26.710  150.728 1.00 15.93  ? 95  LEU C CD2 1 
ATOM 3121 N N   . LYS C 1 96  ? -20.552 30.720  148.027 1.00 16.07  ? 96  LYS C N   1 
ATOM 3122 C CA  . LYS C 1 96  ? -21.147 30.872  146.669 1.00 16.07  ? 96  LYS C CA  1 
ATOM 3123 C C   . LYS C 1 96  ? -20.067 31.382  145.710 1.00 16.07  ? 96  LYS C C   1 
ATOM 3124 O O   . LYS C 1 96  ? -19.986 30.811  144.622 1.00 16.07  ? 96  LYS C O   1 
ATOM 3125 C CB  . LYS C 1 96  ? -22.371 31.772  146.696 1.00 16.07  ? 96  LYS C CB  1 
ATOM 3126 C CG  . LYS C 1 96  ? -23.532 31.244  147.520 1.00 16.07  ? 96  LYS C CG  1 
ATOM 3127 C CD  . LYS C 1 96  ? -24.624 32.255  147.715 1.00 16.07  ? 96  LYS C CD  1 
ATOM 3128 C CE  . LYS C 1 96  ? -25.819 31.666  148.426 1.00 16.07  ? 96  LYS C CE  1 
ATOM 3129 N NZ  . LYS C 1 96  ? -26.491 30.643  147.593 1.00 16.07  ? 96  LYS C NZ  1 
ATOM 3130 N N   . PHE C 1 97  ? -19.213 32.329  146.117 1.00 14.29  ? 97  PHE C N   1 
ATOM 3131 C CA  . PHE C 1 97  ? -18.112 32.883  145.292 1.00 14.29  ? 97  PHE C CA  1 
ATOM 3132 C C   . PHE C 1 97  ? -17.046 31.828  145.019 1.00 14.29  ? 97  PHE C C   1 
ATOM 3133 O O   . PHE C 1 97  ? -16.630 31.740  143.895 1.00 14.29  ? 97  PHE C O   1 
ATOM 3134 C CB  . PHE C 1 97  ? -17.471 34.077  145.997 1.00 30.00  ? 97  PHE C CB  1 
ATOM 3135 C CG  . PHE C 1 97  ? -16.502 34.897  145.188 1.00 30.00  ? 97  PHE C CG  1 
ATOM 3136 C CD1 . PHE C 1 97  ? -16.848 35.394  143.941 1.00 30.00  ? 97  PHE C CD1 1 
ATOM 3137 C CD2 . PHE C 1 97  ? -15.261 35.226  145.704 1.00 30.00  ? 97  PHE C CD2 1 
ATOM 3138 C CE1 . PHE C 1 97  ? -15.961 36.171  143.213 1.00 30.00  ? 97  PHE C CE1 1 
ATOM 3139 C CE2 . PHE C 1 97  ? -14.379 36.008  144.976 1.00 30.00  ? 97  PHE C CE2 1 
ATOM 3140 C CZ  . PHE C 1 97  ? -14.727 36.475  143.730 1.00 30.00  ? 97  PHE C CZ  1 
ATOM 3141 N N   . ARG C 1 98  ? -16.596 31.096  146.027 1.00 13.69  ? 98  ARG C N   1 
ATOM 3142 C CA  . ARG C 1 98  ? -15.513 30.095  145.914 1.00 13.69  ? 98  ARG C CA  1 
ATOM 3143 C C   . ARG C 1 98  ? -15.908 29.074  144.854 1.00 13.69  ? 98  ARG C C   1 
ATOM 3144 O O   . ARG C 1 98  ? -15.071 28.776  143.997 1.00 13.69  ? 98  ARG C O   1 
ATOM 3145 C CB  . ARG C 1 98  ? -15.267 29.452  147.276 1.00 13.69  ? 98  ARG C CB  1 
ATOM 3146 C CG  . ARG C 1 98  ? -14.607 30.372  148.289 1.00 13.69  ? 98  ARG C CG  1 
ATOM 3147 C CD  . ARG C 1 98  ? -14.798 29.830  149.685 1.00 13.69  ? 98  ARG C CD  1 
ATOM 3148 N NE  . ARG C 1 98  ? -14.423 28.427  149.749 1.00 13.69  ? 98  ARG C NE  1 
ATOM 3149 C CZ  . ARG C 1 98  ? -14.902 27.551  150.623 1.00 13.69  ? 98  ARG C CZ  1 
ATOM 3150 N NH1 . ARG C 1 98  ? -15.800 27.916  151.519 1.00 13.69  ? 98  ARG C NH1 1 
ATOM 3151 N NH2 . ARG C 1 98  ? -14.488 26.298  150.587 1.00 13.69  ? 98  ARG C NH2 1 
ATOM 3152 N N   . GLN C 1 99  ? -17.147 28.616  144.869 1.00 13.40  ? 99  GLN C N   1 
ATOM 3153 C CA  . GLN C 1 99  ? -17.592 27.572  143.920 1.00 13.40  ? 99  GLN C CA  1 
ATOM 3154 C C   . GLN C 1 99  ? -17.487 28.131  142.501 1.00 13.40  ? 99  GLN C C   1 
ATOM 3155 O O   . GLN C 1 99  ? -16.901 27.459  141.652 1.00 13.40  ? 99  GLN C O   1 
ATOM 3156 C CB  . GLN C 1 99  ? -19.000 27.109  144.278 1.00 13.40  ? 99  GLN C CB  1 
ATOM 3157 C CG  . GLN C 1 99  ? -19.033 26.215  145.504 1.00 13.40  ? 99  GLN C CG  1 
ATOM 3158 C CD  . GLN C 1 99  ? -20.353 25.504  145.658 1.00 13.40  ? 99  GLN C CD  1 
ATOM 3159 O OE1 . GLN C 1 99  ? -20.776 24.745  144.790 1.00 13.40  ? 99  GLN C OE1 1 
ATOM 3160 N NE2 . GLN C 1 99  ? -21.015 25.752  146.775 1.00 13.40  ? 99  GLN C NE2 1 
ATOM 3161 N N   . LEU C 1 100 ? -17.990 29.330  142.258 1.00 12.83  ? 100 LEU C N   1 
ATOM 3162 C CA  . LEU C 1 100 ? -18.008 29.906  140.892 1.00 12.83  ? 100 LEU C CA  1 
ATOM 3163 C C   . LEU C 1 100 ? -16.576 30.162  140.432 1.00 12.83  ? 100 LEU C C   1 
ATOM 3164 O O   . LEU C 1 100 ? -16.251 29.769  139.309 1.00 12.83  ? 100 LEU C O   1 
ATOM 3165 C CB  . LEU C 1 100 ? -18.821 31.198  140.875 1.00 12.83  ? 100 LEU C CB  1 
ATOM 3166 C CG  . LEU C 1 100 ? -19.074 31.784  139.490 1.00 12.83  ? 100 LEU C CG  1 
ATOM 3167 C CD1 . LEU C 1 100 ? -20.420 32.478  139.431 1.00 12.83  ? 100 LEU C CD1 1 
ATOM 3168 C CD2 . LEU C 1 100 ? -17.960 32.739  139.098 1.00 12.83  ? 100 LEU C CD2 1 
ATOM 3169 N N   . LEU C 1 101 ? -15.746 30.776  141.267 1.00 13.20  ? 101 LEU C N   1 
ATOM 3170 C CA  . LEU C 1 101 ? -14.345 31.083  140.902 1.00 13.20  ? 101 LEU C CA  1 
ATOM 3171 C C   . LEU C 1 101 ? -13.661 29.781  140.508 1.00 13.20  ? 101 LEU C C   1 
ATOM 3172 O O   . LEU C 1 101 ? -13.026 29.756  139.453 1.00 13.20  ? 101 LEU C O   1 
ATOM 3173 C CB  . LEU C 1 101 ? -13.629 31.735  142.082 1.00 13.20  ? 101 LEU C CB  1 
ATOM 3174 C CG  . LEU C 1 101 ? -13.608 33.260  142.100 1.00 13.20  ? 101 LEU C CG  1 
ATOM 3175 C CD1 . LEU C 1 101 ? -12.793 33.764  143.278 1.00 13.20  ? 101 LEU C CD1 1 
ATOM 3176 C CD2 . LEU C 1 101 ? -13.051 33.816  140.802 1.00 13.20  ? 101 LEU C CD2 1 
ATOM 3177 N N   . TRP C 1 102 ? -13.807 28.730  141.306 1.00 12.01  ? 102 TRP C N   1 
ATOM 3178 C CA  . TRP C 1 102 ? -13.152 27.433  141.024 1.00 12.01  ? 102 TRP C CA  1 
ATOM 3179 C C   . TRP C 1 102 ? -13.608 26.960  139.653 1.00 12.01  ? 102 TRP C C   1 
ATOM 3180 O O   . TRP C 1 102 ? -12.743 26.633  138.842 1.00 12.01  ? 102 TRP C O   1 
ATOM 3181 C CB  . TRP C 1 102 ? -13.472 26.405  142.105 1.00 12.01  ? 102 TRP C CB  1 
ATOM 3182 C CG  . TRP C 1 102 ? -13.021 25.018  141.780 1.00 12.01  ? 102 TRP C CG  1 
ATOM 3183 C CD1 . TRP C 1 102 ? -11.840 24.434  142.127 1.00 12.01  ? 102 TRP C CD1 1 
ATOM 3184 C CD2 . TRP C 1 102 ? -13.756 24.030  141.042 1.00 12.01  ? 102 TRP C CD2 1 
ATOM 3185 N NE1 . TRP C 1 102 ? -11.787 23.152  141.652 1.00 12.01  ? 102 TRP C NE1 1 
ATOM 3186 C CE2 . TRP C 1 102 ? -12.949 22.876  140.982 1.00 12.01  ? 102 TRP C CE2 1 
ATOM 3187 C CE3 . TRP C 1 102 ? -15.011 24.008  140.426 1.00 12.01  ? 102 TRP C CE3 1 
ATOM 3188 C CZ2 . TRP C 1 102 ? -13.358 21.716  140.330 1.00 12.01  ? 102 TRP C CZ2 1 
ATOM 3189 C CZ3 . TRP C 1 102 ? -15.413 22.862  139.781 1.00 12.01  ? 102 TRP C CZ3 1 
ATOM 3190 C CH2 . TRP C 1 102 ? -14.598 21.733  139.736 1.00 12.01  ? 102 TRP C CH2 1 
ATOM 3191 N N   . PHE C 1 103 ? -14.905 26.978  139.378 1.00 12.18  ? 103 PHE C N   1 
ATOM 3192 C CA  . PHE C 1 103 ? -15.454 26.450  138.108 1.00 12.18  ? 103 PHE C CA  1 
ATOM 3193 C C   . PHE C 1 103 ? -14.852 27.200  136.930 1.00 12.18  ? 103 PHE C C   1 
ATOM 3194 O O   . PHE C 1 103 ? -14.281 26.543  136.059 1.00 12.18  ? 103 PHE C O   1 
ATOM 3195 C CB  . PHE C 1 103 ? -16.974 26.568  138.084 1.00 12.18  ? 103 PHE C CB  1 
ATOM 3196 C CG  . PHE C 1 103 ? -17.626 26.087  136.817 1.00 12.18  ? 103 PHE C CG  1 
ATOM 3197 C CD1 . PHE C 1 103 ? -17.863 24.740  136.612 1.00 12.18  ? 103 PHE C CD1 1 
ATOM 3198 C CD2 . PHE C 1 103 ? -18.016 26.984  135.838 1.00 12.18  ? 103 PHE C CD2 1 
ATOM 3199 C CE1 . PHE C 1 103 ? -18.467 24.299  135.445 1.00 12.18  ? 103 PHE C CE1 1 
ATOM 3200 C CE2 . PHE C 1 103 ? -18.622 26.541  134.674 1.00 12.18  ? 103 PHE C CE2 1 
ATOM 3201 C CZ  . PHE C 1 103 ? -18.847 25.201  134.481 1.00 12.18  ? 103 PHE C CZ  1 
ATOM 3202 N N   . HIS C 1 104 ? -14.949 28.522  136.900 1.00 12.28  ? 104 HIS C N   1 
ATOM 3203 C CA  . HIS C 1 104 ? -14.488 29.324  135.744 1.00 12.28  ? 104 HIS C CA  1 
ATOM 3204 C C   . HIS C 1 104 ? -12.973 29.230  135.632 1.00 12.28  ? 104 HIS C C   1 
ATOM 3205 O O   . HIS C 1 104 ? -12.491 28.903  134.547 1.00 12.28  ? 104 HIS C O   1 
ATOM 3206 C CB  . HIS C 1 104 ? -15.059 30.735  135.824 1.00 12.28  ? 104 HIS C CB  1 
ATOM 3207 C CG  . HIS C 1 104 ? -16.510 30.805  135.500 1.00 12.28  ? 104 HIS C CG  1 
ATOM 3208 N ND1 . HIS C 1 104 ? -17.408 31.473  136.301 1.00 12.28  ? 104 HIS C ND1 1 
ATOM 3209 C CD2 . HIS C 1 104 ? -17.219 30.297  134.474 1.00 12.28  ? 104 HIS C CD2 1 
ATOM 3210 C CE1 . HIS C 1 104 ? -18.610 31.379  135.781 1.00 12.28  ? 104 HIS C CE1 1 
ATOM 3211 N NE2 . HIS C 1 104 ? -18.523 30.663  134.660 1.00 12.28  ? 104 HIS C NE2 1 
ATOM 3212 N N   . ILE C 1 105 ? -12.251 29.486  136.716 1.00 12.75  ? 105 ILE C N   1 
ATOM 3213 C CA  . ILE C 1 105 ? -10.765 29.457  136.691 1.00 12.75  ? 105 ILE C CA  1 
ATOM 3214 C C   . ILE C 1 105 ? -10.376 28.079  136.182 1.00 12.75  ? 105 ILE C C   1 
ATOM 3215 O O   . ILE C 1 105 ? -9.617  28.032  135.234 1.00 12.75  ? 105 ILE C O   1 
ATOM 3216 C CB  . ILE C 1 105 ? -10.153 29.763  138.066 1.00 12.75  ? 105 ILE C CB  1 
ATOM 3217 C CG1 . ILE C 1 105 ? -10.494 31.176  138.537 1.00 12.75  ? 105 ILE C CG1 1 
ATOM 3218 C CG2 . ILE C 1 105 ? -8.653  29.533  138.039 1.00 12.75  ? 105 ILE C CG2 1 
ATOM 3219 C CD1 . ILE C 1 105 ? -10.168 31.432  139.987 1.00 12.75  ? 105 ILE C CD1 1 
ATOM 3220 N N   . SER C 1 106 ? -10.967 27.015  136.708 1.00 13.22  ? 106 SER C N   1 
ATOM 3221 C CA  . SER C 1 106 ? -10.633 25.620  136.338 1.00 13.22  ? 106 SER C CA  1 
ATOM 3222 C C   . SER C 1 106 ? -11.055 25.319  134.905 1.00 13.22  ? 106 SER C C   1 
ATOM 3223 O O   . SER C 1 106 ? -10.416 24.480  134.301 1.00 13.22  ? 106 SER C O   1 
ATOM 3224 C CB  . SER C 1 106 ? -11.275 24.662  137.276 1.00 13.22  ? 106 SER C CB  1 
ATOM 3225 O OG  . SER C 1 106 ? -10.803 24.860  138.598 1.00 13.22  ? 106 SER C OG  1 
ATOM 3226 N N   . CYS C 1 107 ? -12.130 25.914  134.410 1.00 13.10  ? 107 CYS C N   1 
ATOM 3227 C CA  . CYS C 1 107 ? -12.628 25.677  133.036 1.00 13.10  ? 107 CYS C CA  1 
ATOM 3228 C C   . CYS C 1 107 ? -11.657 26.324  132.062 1.00 13.10  ? 107 CYS C C   1 
ATOM 3229 O O   . CYS C 1 107 ? -11.519 25.812  130.952 1.00 13.10  ? 107 CYS C O   1 
ATOM 3230 C CB  . CYS C 1 107 ? -14.023 26.244  132.835 1.00 13.10  ? 107 CYS C CB  1 
ATOM 3231 S SG  . CYS C 1 107 ? -15.343 25.142  133.399 1.00 13.10  ? 107 CYS C SG  1 
ATOM 3232 N N   . LEU C 1 108 ? -11.006 27.405  132.470 1.00 12.74  ? 108 LEU C N   1 
ATOM 3233 C CA  . LEU C 1 108 ? -10.020 28.106  131.621 1.00 12.74  ? 108 LEU C CA  1 
ATOM 3234 C C   . LEU C 1 108 ? -8.710  27.328  131.679 1.00 12.74  ? 108 LEU C C   1 
ATOM 3235 O O   . LEU C 1 108 ? -8.053  27.239  130.640 1.00 12.74  ? 108 LEU C O   1 
ATOM 3236 C CB  . LEU C 1 108 ? -9.841  29.539  132.120 1.00 12.74  ? 108 LEU C CB  1 
ATOM 3237 C CG  . LEU C 1 108 ? -11.032 30.469  131.907 1.00 12.74  ? 108 LEU C CG  1 
ATOM 3238 C CD1 . LEU C 1 108 ? -10.833 31.774  132.655 1.00 12.74  ? 108 LEU C CD1 1 
ATOM 3239 C CD2 . LEU C 1 108 ? -11.256 30.733  130.431 1.00 12.74  ? 108 LEU C CD2 1 
ATOM 3240 N N   . THR C 1 109 ? -8.348  26.775  132.839 1.00 13.31  ? 109 THR C N   1 
ATOM 3241 C CA  . THR C 1 109 ? -7.072  26.074  132.968 1.00 13.31  ? 109 THR C CA  1 
ATOM 3242 C C   . THR C 1 109 ? -7.092  24.712  132.279 1.00 13.31  ? 109 THR C C   1 
ATOM 3243 O O   . THR C 1 109 ? -6.171  24.375  131.526 1.00 13.31  ? 109 THR C O   1 
ATOM 3244 C CB  . THR C 1 109 ? -6.715  25.918  134.447 1.00 13.31  ? 109 THR C CB  1 
ATOM 3245 O OG1 . THR C 1 109 ? -6.809  27.190  135.098 1.00 13.31  ? 109 THR C OG1 1 
ATOM 3246 C CG2 . THR C 1 109 ? -5.298  25.388  134.603 1.00 13.31  ? 109 THR C CG2 1 
ATOM 3247 N N   . PHE C 1 110 ? -8.134  23.913  132.523 1.00 15.07  ? 110 PHE C N   1 
ATOM 3248 C CA  . PHE C 1 110 ? -8.180  22.522  132.083 1.00 15.07  ? 110 PHE C CA  1 
ATOM 3249 C C   . PHE C 1 110 ? -9.214  22.243  131.000 1.00 15.07  ? 110 PHE C C   1 
ATOM 3250 O O   . PHE C 1 110 ? -9.256  21.119  130.490 1.00 15.07  ? 110 PHE C O   1 
ATOM 3251 C CB  . PHE C 1 110 ? -8.449  21.601  133.281 1.00 15.07  ? 110 PHE C CB  1 
ATOM 3252 C CG  . PHE C 1 110 ? -7.564  21.873  134.460 1.00 15.07  ? 110 PHE C CG  1 
ATOM 3253 C CD1 . PHE C 1 110 ? -6.263  21.400  134.493 1.00 15.07  ? 110 PHE C CD1 1 
ATOM 3254 C CD2 . PHE C 1 110 ? -8.032  22.607  135.536 1.00 15.07  ? 110 PHE C CD2 1 
ATOM 3255 C CE1 . PHE C 1 110 ? -5.448  21.655  135.576 1.00 15.07  ? 110 PHE C CE1 1 
ATOM 3256 C CE2 . PHE C 1 110 ? -7.220  22.868  136.619 1.00 15.07  ? 110 PHE C CE2 1 
ATOM 3257 C CZ  . PHE C 1 110 ? -5.928  22.389  136.641 1.00 15.07  ? 110 PHE C CZ  1 
ATOM 3258 N N   . GLY C 1 111 ? -10.033 23.221  130.631 1.00 15.50  ? 111 GLY C N   1 
ATOM 3259 C CA  . GLY C 1 111 ? -11.126 23.007  129.700 1.00 15.50  ? 111 GLY C CA  1 
ATOM 3260 C C   . GLY C 1 111 ? -12.424 22.567  130.349 1.00 15.50  ? 111 GLY C C   1 
ATOM 3261 O O   . GLY C 1 111 ? -12.452 21.760  131.281 1.00 15.50  ? 111 GLY C O   1 
ATOM 3262 N N   . ARG C 1 112 ? -13.516 23.161  129.859 1.00 15.30  ? 112 ARG C N   1 
ATOM 3263 C CA  . ARG C 1 112 ? -14.863 22.964  130.439 1.00 15.30  ? 112 ARG C CA  1 
ATOM 3264 C C   . ARG C 1 112 ? -15.210 21.496  130.543 1.00 15.30  ? 112 ARG C C   1 
ATOM 3265 O O   . ARG C 1 112 ? -15.569 21.073  131.630 1.00 15.30  ? 112 ARG C O   1 
ATOM 3266 C CB  . ARG C 1 112 ? -15.908 23.654  129.565 1.00 15.30  ? 112 ARG C CB  1 
ATOM 3267 C CG  . ARG C 1 112 ? -17.212 23.962  130.283 1.00 15.30  ? 112 ARG C CG  1 
ATOM 3268 C CD  . ARG C 1 112 ? -18.114 24.809  129.416 1.00 15.30  ? 112 ARG C CD  1 
ATOM 3269 N NE  . ARG C 1 112 ? -18.285 24.195  128.110 1.00 15.30  ? 112 ARG C NE  1 
ATOM 3270 C CZ  . ARG C 1 112 ? -19.083 23.167  127.859 1.00 15.30  ? 112 ARG C CZ  1 
ATOM 3271 N NH1 . ARG C 1 112 ? -19.798 22.620  128.828 1.00 15.30  ? 112 ARG C NH1 1 
ATOM 3272 N NH2 . ARG C 1 112 ? -19.159 22.680  126.635 1.00 15.30  ? 112 ARG C NH2 1 
ATOM 3273 N N   . GLU C 1 113 ? -15.140 20.757  129.450 1.00 18.27  ? 113 GLU C N   1 
ATOM 3274 C CA  . GLU C 1 113 ? -15.562 19.357  129.481 1.00 18.27  ? 113 GLU C CA  1 
ATOM 3275 C C   . GLU C 1 113 ? -14.754 18.543  130.486 1.00 18.27  ? 113 GLU C C   1 
ATOM 3276 O O   . GLU C 1 113 ? -15.299 17.664  131.172 1.00 18.27  ? 113 GLU C O   1 
ATOM 3277 C CB  . GLU C 1 113 ? -15.455 18.753  128.074 1.00 18.27  ? 113 GLU C CB  1 
ATOM 3278 C CG  . GLU C 1 113 ? -14.032 18.568  127.541 1.00 18.27  ? 113 GLU C CG  1 
ATOM 3279 C CD  . GLU C 1 113 ? -13.480 19.823  126.892 1.00 18.27  ? 113 GLU C CD  1 
ATOM 3280 O OE1 . GLU C 1 113 ? -14.038 20.914  127.130 1.00 18.27  ? 113 GLU C OE1 1 
ATOM 3281 O OE2 . GLU C 1 113 ? -12.482 19.718  126.149 1.00 18.27  ? 113 GLU C OE2 1 
ATOM 3282 N N   . THR C 1 114 ? -13.461 18.845  130.616 1.00 17.22  ? 114 THR C N   1 
ATOM 3283 C CA  . THR C 1 114 ? -12.644 18.191  131.630 1.00 17.22  ? 114 THR C CA  1 
ATOM 3284 C C   . THR C 1 114 ? -13.155 18.477  133.035 1.00 17.22  ? 114 THR C C   1 
ATOM 3285 O O   . THR C 1 114 ? -13.198 17.581  133.880 1.00 17.22  ? 114 THR C O   1 
ATOM 3286 C CB  . THR C 1 114 ? -11.186 18.630  131.497 1.00 17.22  ? 114 THR C CB  1 
ATOM 3287 O OG1 . THR C 1 114 ? -10.804 18.604  130.117 1.00 17.22  ? 114 THR C OG1 1 
ATOM 3288 C CG2 . THR C 1 114 ? -10.278 17.700  132.287 1.00 17.22  ? 114 THR C CG2 1 
ATOM 3289 N N   . VAL C 1 115 ? -13.550 19.723  133.299 1.00 14.45  ? 115 VAL C N   1 
ATOM 3290 C CA  . VAL C 1 115 ? -14.054 20.078  134.622 1.00 14.45  ? 115 VAL C CA  1 
ATOM 3291 C C   . VAL C 1 115 ? -15.387 19.393  134.913 1.00 14.45  ? 115 VAL C C   1 
ATOM 3292 O O   . VAL C 1 115 ? -15.623 18.936  136.035 1.00 14.45  ? 115 VAL C O   1 
ATOM 3293 C CB  . VAL C 1 115 ? -14.159 21.610  134.743 1.00 14.45  ? 115 VAL C CB  1 
ATOM 3294 C CG1 . VAL C 1 115 ? -14.777 22.011  136.070 1.00 14.45  ? 115 VAL C CG1 1 
ATOM 3295 C CG2 . VAL C 1 115 ? -12.785 22.239  134.598 1.00 14.45  ? 115 VAL C CG2 1 
ATOM 3296 N N   . ILE C 1 116 ? -16.288 19.335  133.933 1.00 15.39  ? 116 ILE C N   1 
ATOM 3297 C CA  . ILE C 1 116 ? -17.544 18.610  134.141 1.00 15.39  ? 116 ILE C CA  1 
ATOM 3298 C C   . ILE C 1 116 ? -17.319 17.124  134.423 1.00 15.39  ? 116 ILE C C   1 
ATOM 3299 O O   . ILE C 1 116 ? -17.908 16.557  135.361 1.00 15.39  ? 116 ILE C O   1 
ATOM 3300 C CB  . ILE C 1 116 ? -18.464 18.775  132.916 1.00 30.00  ? 116 ILE C CB  1 
ATOM 3301 C CG1 . ILE C 1 116 ? -18.895 20.235  132.766 1.00 30.00  ? 116 ILE C CG1 1 
ATOM 3302 C CG2 . ILE C 1 116 ? -19.677 17.867  133.036 1.00 30.00  ? 116 ILE C CG2 1 
ATOM 3303 C CD1 . ILE C 1 116 ? -19.579 20.536  131.451 1.00 30.00  ? 116 ILE C CD1 1 
ATOM 3304 N N   . GLU C 1 117 ? -16.436 16.485  133.650 1.00 16.07  ? 117 GLU C N   1 
ATOM 3305 C CA  . GLU C 1 117 ? -16.112 15.087  133.916 1.00 16.07  ? 117 GLU C CA  1 
ATOM 3306 C C   . GLU C 1 117 ? -15.457 14.917  135.280 1.00 16.07  ? 117 GLU C C   1 
ATOM 3307 O O   . GLU C 1 117 ? -15.717 13.934  135.982 1.00 16.07  ? 117 GLU C O   1 
ATOM 3308 C CB  . GLU C 1 117 ? -15.207 14.541  132.811 1.00 16.07  ? 117 GLU C CB  1 
ATOM 3309 C CG  . GLU C 1 117 ? -15.893 14.401  131.464 1.00 16.07  ? 117 GLU C CG  1 
ATOM 3310 C CD  . GLU C 1 117 ? -14.960 13.883  130.385 1.00 16.07  ? 117 GLU C CD  1 
ATOM 3311 O OE1 . GLU C 1 117 ? -13.770 13.649  130.687 1.00 16.07  ? 117 GLU C OE1 1 
ATOM 3312 O OE2 . GLU C 1 117 ? -15.414 13.719  129.233 1.00 16.07  ? 117 GLU C OE2 1 
ATOM 3313 N N   . TYR C 1 118 ? -14.609 15.865  135.678 1.00 14.43  ? 118 TYR C N   1 
ATOM 3314 C CA  . TYR C 1 118 ? -13.999 15.800  137.000 1.00 14.43  ? 118 TYR C CA  1 
ATOM 3315 C C   . TYR C 1 118 ? -15.041 15.926  138.103 1.00 14.43  ? 118 TYR C C   1 
ATOM 3316 O O   . TYR C 1 118 ? -14.980 15.207  139.102 1.00 14.43  ? 118 TYR C O   1 
ATOM 3317 C CB  . TYR C 1 118 ? -12.950 16.900  137.142 1.00 14.43  ? 118 TYR C CB  1 
ATOM 3318 C CG  . TYR C 1 118 ? -12.266 16.907  138.487 1.00 14.43  ? 118 TYR C CG  1 
ATOM 3319 C CD1 . TYR C 1 118 ? -11.290 15.974  138.800 1.00 14.43  ? 118 TYR C CD1 1 
ATOM 3320 C CD2 . TYR C 1 118 ? -12.624 17.833  139.456 1.00 14.43  ? 118 TYR C CD2 1 
ATOM 3321 C CE1 . TYR C 1 118 ? -10.678 15.974  140.035 1.00 14.43  ? 118 TYR C CE1 1 
ATOM 3322 C CE2 . TYR C 1 118 ? -12.011 17.846  140.689 1.00 14.43  ? 118 TYR C CE2 1 
ATOM 3323 C CZ  . TYR C 1 118 ? -11.039 16.915  140.974 1.00 14.43  ? 118 TYR C CZ  1 
ATOM 3324 O OH  . TYR C 1 118 ? -10.434 16.923  142.209 1.00 14.43  ? 118 TYR C OH  1 
ATOM 3325 N N   . LEU C 1 119 ? -16.002 16.834  137.946 1.00 14.00  ? 119 LEU C N   1 
ATOM 3326 C CA  . LEU C 1 119 ? -17.053 16.976  138.949 1.00 14.00  ? 119 LEU C CA  1 
ATOM 3327 C C   . LEU C 1 119 ? -17.821 15.675  139.128 1.00 14.00  ? 119 LEU C C   1 
ATOM 3328 O O   . LEU C 1 119 ? -17.964 15.171  140.253 1.00 14.00  ? 119 LEU C O   1 
ATOM 3329 C CB  . LEU C 1 119 ? -18.010 18.103  138.550 1.00 14.00  ? 119 LEU C CB  1 
ATOM 3330 C CG  . LEU C 1 119 ? -17.504 19.540  138.656 1.00 14.00  ? 119 LEU C CG  1 
ATOM 3331 C CD1 . LEU C 1 119 ? -18.399 20.481  137.867 1.00 14.00  ? 119 LEU C CD1 1 
ATOM 3332 C CD2 . LEU C 1 119 ? -17.438 19.965  140.111 1.00 14.00  ? 119 LEU C CD2 1 
ATOM 3333 N N   . VAL C 1 120 ? -18.230 15.061  138.018 1.00 14.39  ? 120 VAL C N   1 
ATOM 3334 C CA  . VAL C 1 120 ? -18.956 13.792  138.100 1.00 14.39  ? 120 VAL C CA  1 
ATOM 3335 C C   . VAL C 1 120 ? -18.095 12.709  138.750 1.00 14.39  ? 120 VAL C C   1 
ATOM 3336 O O   . VAL C 1 120 ? -18.527 12.028  139.692 1.00 14.39  ? 120 VAL C O   1 
ATOM 3337 C CB  . VAL C 1 120 ? -19.445 13.368  136.703 1.00 14.39  ? 120 VAL C CB  1 
ATOM 3338 C CG1 . VAL C 1 120 ? -19.852 11.898  136.688 1.00 14.39  ? 120 VAL C CG1 1 
ATOM 3339 C CG2 . VAL C 1 120 ? -20.600 14.250  136.258 1.00 14.39  ? 120 VAL C CG2 1 
ATOM 3340 N N   . SER C 1 121 ? -16.864 12.537  138.267 1.00 14.85  ? 121 SER C N   1 
ATOM 3341 C CA  . SER C 1 121 ? -16.058 11.400  138.692 1.00 14.85  ? 121 SER C CA  1 
ATOM 3342 C C   . SER C 1 121 ? -15.556 11.555  140.123 1.00 14.85  ? 121 SER C C   1 
ATOM 3343 O O   . SER C 1 121 ? -15.525 10.579  140.879 1.00 14.85  ? 121 SER C O   1 
ATOM 3344 C CB  . SER C 1 121 ? -14.882 11.209  137.735 1.00 14.85  ? 121 SER C CB  1 
ATOM 3345 O OG  . SER C 1 121 ? -14.018 12.331  137.756 1.00 14.85  ? 121 SER C OG  1 
ATOM 3346 N N   . PHE C 1 122 ? -15.205 12.774  140.537 1.00 14.06  ? 122 PHE C N   1 
ATOM 3347 C CA  . PHE C 1 122 ? -14.847 13.001  141.932 1.00 14.06  ? 122 PHE C CA  1 
ATOM 3348 C C   . PHE C 1 122 ? -16.044 12.822  142.857 1.00 14.06  ? 122 PHE C C   1 
ATOM 3349 O O   . PHE C 1 122 ? -15.899 12.281  143.960 1.00 14.06  ? 122 PHE C O   1 
ATOM 3350 C CB  . PHE C 1 122 ? -14.253 14.402  142.093 1.00 14.06  ? 122 PHE C CB  1 
ATOM 3351 C CG  . PHE C 1 122 ? -13.805 14.716  143.494 1.00 14.06  ? 122 PHE C CG  1 
ATOM 3352 C CD1 . PHE C 1 122 ? -14.687 15.234  144.423 1.00 14.06  ? 122 PHE C CD1 1 
ATOM 3353 C CD2 . PHE C 1 122 ? -12.502 14.467  143.885 1.00 14.06  ? 122 PHE C CD2 1 
ATOM 3354 C CE1 . PHE C 1 122 ? -14.275 15.506  145.714 1.00 14.06  ? 122 PHE C CE1 1 
ATOM 3355 C CE2 . PHE C 1 122 ? -12.080 14.753  145.167 1.00 14.06  ? 122 PHE C CE2 1 
ATOM 3356 C CZ  . PHE C 1 122 ? -12.966 15.278  146.081 1.00 14.06  ? 122 PHE C CZ  1 
ATOM 3357 N N   . GLY C 1 123 ? -17.227 13.304  142.466 1.00 12.92  ? 123 GLY C N   1 
ATOM 3358 C CA  . GLY C 1 123 ? -18.393 13.077  143.302 1.00 12.92  ? 123 GLY C CA  1 
ATOM 3359 C C   . GLY C 1 123 ? -18.700 11.603  143.503 1.00 12.92  ? 123 GLY C C   1 
ATOM 3360 O O   . GLY C 1 123 ? -18.973 11.156  144.623 1.00 12.92  ? 123 GLY C O   1 
ATOM 3361 N N   . VAL C 1 124 ? -18.630 10.820  142.426 1.00 12.73  ? 124 VAL C N   1 
ATOM 3362 C CA  . VAL C 1 124 ? -18.812 9.375   142.556 1.00 12.73  ? 124 VAL C CA  1 
ATOM 3363 C C   . VAL C 1 124 ? -17.695 8.731   143.375 1.00 12.73  ? 124 VAL C C   1 
ATOM 3364 O O   . VAL C 1 124 ? -17.935 7.778   144.124 1.00 12.73  ? 124 VAL C O   1 
ATOM 3365 C CB  . VAL C 1 124 ? -18.926 8.735   141.159 1.00 12.73  ? 124 VAL C CB  1 
ATOM 3366 C CG1 . VAL C 1 124 ? -18.917 7.214   141.258 1.00 12.73  ? 124 VAL C CG1 1 
ATOM 3367 C CG2 . VAL C 1 124 ? -20.188 9.218   140.460 1.00 12.73  ? 124 VAL C CG2 1 
ATOM 3368 N N   . TRP C 1 125 ? -16.460 9.229   143.257 1.00 12.80  ? 125 TRP C N   1 
ATOM 3369 C CA  . TRP C 1 125 ? -15.370 8.693   144.069 1.00 12.80  ? 125 TRP C CA  1 
ATOM 3370 C C   . TRP C 1 125 ? -15.569 8.954   145.560 1.00 12.80  ? 125 TRP C C   1 
ATOM 3371 O O   . TRP C 1 125 ? -15.314 8.071   146.387 1.00 12.80  ? 125 TRP C O   1 
ATOM 3372 C CB  . TRP C 1 125 ? -14.039 9.285   143.604 1.00 12.80  ? 125 TRP C CB  1 
ATOM 3373 C CG  . TRP C 1 125 ? -12.857 8.783   144.377 1.00 12.80  ? 125 TRP C CG  1 
ATOM 3374 C CD1 . TRP C 1 125 ? -12.071 7.713   144.066 1.00 12.80  ? 125 TRP C CD1 1 
ATOM 3375 C CD2 . TRP C 1 125 ? -12.331 9.325   145.596 1.00 12.80  ? 125 TRP C CD2 1 
ATOM 3376 N NE1 . TRP C 1 125 ? -11.086 7.557   145.009 1.00 12.80  ? 125 TRP C NE1 1 
ATOM 3377 C CE2 . TRP C 1 125 ? -11.225 8.533   145.962 1.00 12.80  ? 125 TRP C CE2 1 
ATOM 3378 C CE3 . TRP C 1 125 ? -12.697 10.393  146.418 1.00 12.80  ? 125 TRP C CE3 1 
ATOM 3379 C CZ2 . TRP C 1 125 ? -10.475 8.782   147.107 1.00 12.80  ? 125 TRP C CZ2 1 
ATOM 3380 C CZ3 . TRP C 1 125 ? -11.947 10.642  147.553 1.00 12.80  ? 125 TRP C CZ3 1 
ATOM 3381 C CH2 . TRP C 1 125 ? -10.853 9.838   147.889 1.00 12.80  ? 125 TRP C CH2 1 
ATOM 3382 N N   . ILE C 1 126 ? -16.025 10.152  145.924 1.00 13.18  ? 126 ILE C N   1 
ATOM 3383 C CA  . ILE C 1 126 ? -16.334 10.429  147.327 1.00 13.18  ? 126 ILE C CA  1 
ATOM 3384 C C   . ILE C 1 126 ? -17.498 9.568   147.810 1.00 13.18  ? 126 ILE C C   1 
ATOM 3385 O O   . ILE C 1 126 ? -17.495 9.089   148.951 1.00 13.18  ? 126 ILE C O   1 
ATOM 3386 C CB  . ILE C 1 126 ? -16.576 11.937  147.554 1.00 13.18  ? 126 ILE C CB  1 
ATOM 3387 C CG1 . ILE C 1 126 ? -16.588 12.265  149.051 1.00 13.18  ? 126 ILE C CG1 1 
ATOM 3388 C CG2 . ILE C 1 126 ? -17.857 12.415  146.914 1.00 13.18  ? 126 ILE C CG2 1 
ATOM 3389 C CD1 . ILE C 1 126 ? -15.254 12.059  149.742 1.00 13.18  ? 126 ILE C CD1 1 
ATOM 3390 N N   . ARG C 1 127 ? -18.513 9.355   146.967 1.00 13.15  ? 127 ARG C N   1 
ATOM 3391 C CA  . ARG C 1 127 ? -19.603 8.460   147.359 1.00 13.15  ? 127 ARG C CA  1 
ATOM 3392 C C   . ARG C 1 127 ? -19.147 7.013   147.544 1.00 13.15  ? 127 ARG C C   1 
ATOM 3393 O O   . ARG C 1 127 ? -19.727 6.292   148.362 1.00 13.15  ? 127 ARG C O   1 
ATOM 3394 C CB  . ARG C 1 127 ? -20.752 8.535   146.353 1.00 13.15  ? 127 ARG C CB  1 
ATOM 3395 C CG  . ARG C 1 127 ? -21.782 9.612   146.682 1.00 13.15  ? 127 ARG C CG  1 
ATOM 3396 C CD  . ARG C 1 127 ? -21.369 10.992  146.231 1.00 13.15  ? 127 ARG C CD  1 
ATOM 3397 N NE  . ARG C 1 127 ? -22.328 12.005  146.654 1.00 13.15  ? 127 ARG C NE  1 
ATOM 3398 C CZ  . ARG C 1 127 ? -22.103 13.311  146.621 1.00 13.15  ? 127 ARG C CZ  1 
ATOM 3399 N NH1 . ARG C 1 127 ? -20.969 13.807  146.155 1.00 13.15  ? 127 ARG C NH1 1 
ATOM 3400 N NH2 . ARG C 1 127 ? -23.042 14.141  147.066 1.00 13.15  ? 127 ARG C NH2 1 
ATOM 3401 N N   . THR C 1 128 ? -18.131 6.563   146.813 1.00 12.32  ? 128 THR C N   1 
ATOM 3402 C CA  . THR C 1 128 ? -17.767 5.149   146.857 1.00 12.32  ? 128 THR C CA  1 
ATOM 3403 C C   . THR C 1 128 ? -17.060 4.822   148.176 1.00 12.32  ? 128 THR C C   1 
ATOM 3404 O O   . THR C 1 128 ? -16.212 5.593   148.635 1.00 12.32  ? 128 THR C O   1 
ATOM 3405 C CB  . THR C 1 128 ? -16.861 4.787   145.681 1.00 12.32  ? 128 THR C CB  1 
ATOM 3406 O OG1 . THR C 1 128 ? -17.507 5.134   144.451 1.00 12.32  ? 128 THR C OG1 1 
ATOM 3407 C CG2 . THR C 1 128 ? -16.556 3.294   145.678 1.00 12.32  ? 128 THR C CG2 1 
ATOM 3408 N N   . PRO C 1 129 ? -17.390 3.695   148.810 1.00 11.77  ? 129 PRO C N   1 
ATOM 3409 C CA  . PRO C 1 129 ? -16.666 3.297   150.014 1.00 11.77  ? 129 PRO C CA  1 
ATOM 3410 C C   . PRO C 1 129 ? -15.190 3.084   149.735 1.00 11.77  ? 129 PRO C C   1 
ATOM 3411 O O   . PRO C 1 129 ? -14.801 2.634   148.641 1.00 11.77  ? 129 PRO C O   1 
ATOM 3412 C CB  . PRO C 1 129 ? -17.356 1.989   150.428 1.00 11.77  ? 129 PRO C CB  1 
ATOM 3413 C CG  . PRO C 1 129 ? -18.701 2.057   149.814 1.00 11.77  ? 129 PRO C CG  1 
ATOM 3414 C CD  . PRO C 1 129 ? -18.493 2.766   148.513 1.00 11.77  ? 129 PRO C CD  1 
ATOM 3415 N N   . PRO C 1 130 ? -14.328 3.389   150.711 1.00 11.35  ? 130 PRO C N   1 
ATOM 3416 C CA  . PRO C 1 130 ? -12.874 3.372   150.465 1.00 11.35  ? 130 PRO C CA  1 
ATOM 3417 C C   . PRO C 1 130 ? -12.294 2.013   150.094 1.00 11.35  ? 130 PRO C C   1 
ATOM 3418 O O   . PRO C 1 130 ? -11.286 1.962   149.380 1.00 11.35  ? 130 PRO C O   1 
ATOM 3419 C CB  . PRO C 1 130 ? -12.292 3.873   151.797 1.00 11.35  ? 130 PRO C CB  1 
ATOM 3420 C CG  . PRO C 1 130 ? -13.338 3.564   152.807 1.00 11.35  ? 130 PRO C CG  1 
ATOM 3421 C CD  . PRO C 1 130 ? -14.635 3.788   152.093 1.00 11.35  ? 130 PRO C CD  1 
ATOM 3422 N N   . ALA C 1 131 ? -12.893 0.913   150.554 1.00 10.68  ? 131 ALA C N   1 
ATOM 3423 C CA  . ALA C 1 131 ? -12.382 -0.413  150.218 1.00 10.68  ? 131 ALA C CA  1 
ATOM 3424 C C   . ALA C 1 131 ? -12.533 -0.770  148.746 1.00 10.68  ? 131 ALA C C   1 
ATOM 3425 O O   . ALA C 1 131 ? -11.842 -1.680  148.275 1.00 10.68  ? 131 ALA C O   1 
ATOM 3426 C CB  . ALA C 1 131 ? -13.084 -1.471  151.071 1.00 10.68  ? 131 ALA C CB  1 
ATOM 3427 N N   . TYR C 1 132 ? -13.406 -0.087  148.008 1.00 10.72  ? 132 TYR C N   1 
ATOM 3428 C CA  . TYR C 1 132 ? -13.748 -0.488  146.647 1.00 10.72  ? 132 TYR C CA  1 
ATOM 3429 C C   . TYR C 1 132 ? -13.609 0.678   145.676 1.00 10.72  ? 132 TYR C C   1 
ATOM 3430 O O   . TYR C 1 132 ? -14.318 0.743   144.669 1.00 10.72  ? 132 TYR C O   1 
ATOM 3431 C CB  . TYR C 1 132 ? -15.158 -1.076  146.595 1.00 10.72  ? 132 TYR C CB  1 
ATOM 3432 C CG  . TYR C 1 132 ? -15.394 -2.142  147.640 1.00 10.72  ? 132 TYR C CG  1 
ATOM 3433 C CD1 . TYR C 1 132 ? -14.886 -3.423  147.478 1.00 10.72  ? 132 TYR C CD1 1 
ATOM 3434 C CD2 . TYR C 1 132 ? -16.119 -1.869  148.791 1.00 10.72  ? 132 TYR C CD2 1 
ATOM 3435 C CE1 . TYR C 1 132 ? -15.104 -4.406  148.422 1.00 10.72  ? 132 TYR C CE1 1 
ATOM 3436 C CE2 . TYR C 1 132 ? -16.336 -2.842  149.748 1.00 10.72  ? 132 TYR C CE2 1 
ATOM 3437 C CZ  . TYR C 1 132 ? -15.824 -4.109  149.558 1.00 10.72  ? 132 TYR C CZ  1 
ATOM 3438 O OH  . TYR C 1 132 ? -16.022 -5.078  150.513 1.00 10.72  ? 132 TYR C OH  1 
ATOM 3439 N N   . ARG C 1 133 ? -12.699 1.599   145.962 1.00 12.02  ? 133 ARG C N   1 
ATOM 3440 C CA  . ARG C 1 133 ? -12.360 2.704   145.081 1.00 12.02  ? 133 ARG C CA  1 
ATOM 3441 C C   . ARG C 1 133 ? -10.850 2.834   144.979 1.00 12.02  ? 133 ARG C C   1 
ATOM 3442 O O   . ARG C 1 133 ? -10.116 2.345   145.846 1.00 12.02  ? 133 ARG C O   1 
ATOM 3443 C CB  . ARG C 1 133 ? -12.967 4.015   145.602 1.00 12.02  ? 133 ARG C CB  1 
ATOM 3444 C CG  . ARG C 1 133 ? -12.353 4.498   146.903 1.00 12.02  ? 133 ARG C CG  1 
ATOM 3445 C CD  . ARG C 1 133 ? -13.022 5.760   147.407 1.00 12.02  ? 133 ARG C CD  1 
ATOM 3446 N NE  . ARG C 1 133 ? -12.352 6.291   148.587 1.00 12.02  ? 133 ARG C NE  1 
ATOM 3447 C CZ  . ARG C 1 133 ? -12.872 7.203   149.398 1.00 12.02  ? 133 ARG C CZ  1 
ATOM 3448 N NH1 . ARG C 1 133 ? -14.061 7.733   149.172 1.00 12.02  ? 133 ARG C NH1 1 
ATOM 3449 N NH2 . ARG C 1 133 ? -12.182 7.584   150.469 1.00 12.02  ? 133 ARG C NH2 1 
ATOM 3450 N N   . PRO C 1 134 ? -10.349 3.480   143.928 1.00 13.90  ? 134 PRO C N   1 
ATOM 3451 C CA  . PRO C 1 134 ? -8.916  3.793   143.854 1.00 13.90  ? 134 PRO C CA  1 
ATOM 3452 C C   . PRO C 1 134 ? -8.469  4.643   145.031 1.00 13.90  ? 134 PRO C C   1 
ATOM 3453 O O   . PRO C 1 134 ? -9.215  5.516   145.498 1.00 13.90  ? 134 PRO C O   1 
ATOM 3454 C CB  . PRO C 1 134 ? -8.789  4.561   142.528 1.00 13.90  ? 134 PRO C CB  1 
ATOM 3455 C CG  . PRO C 1 134 ? -9.966  4.124   141.729 1.00 13.90  ? 134 PRO C CG  1 
ATOM 3456 C CD  . PRO C 1 134 ? -11.064 3.955   142.734 1.00 13.90  ? 134 PRO C CD  1 
ATOM 3457 N N   . PRO C 1 135 ? -7.253  4.420   145.539 1.00 15.14  ? 135 PRO C N   1 
ATOM 3458 C CA  . PRO C 1 135 ? -6.915  4.924   146.880 1.00 15.14  ? 135 PRO C CA  1 
ATOM 3459 C C   . PRO C 1 135 ? -6.730  6.432   146.953 1.00 15.14  ? 135 PRO C C   1 
ATOM 3460 O O   . PRO C 1 135 ? -6.889  6.999   148.042 1.00 15.14  ? 135 PRO C O   1 
ATOM 3461 C CB  . PRO C 1 135 ? -5.603  4.194   147.209 1.00 15.14  ? 135 PRO C CB  1 
ATOM 3462 C CG  . PRO C 1 135 ? -5.011  3.881   145.879 1.00 15.14  ? 135 PRO C CG  1 
ATOM 3463 C CD  . PRO C 1 135 ? -6.182  3.567   144.996 1.00 15.14  ? 135 PRO C CD  1 
ATOM 3464 N N   . ASN C 1 136 ? -6.407  7.098   145.848 1.00 16.76  ? 136 ASN C N   1 
ATOM 3465 C CA  . ASN C 1 136 ? -6.111  8.524   145.853 1.00 16.76  ? 136 ASN C CA  1 
ATOM 3466 C C   . ASN C 1 136 ? -7.314  9.339   145.395 1.00 16.76  ? 136 ASN C C   1 
ATOM 3467 O O   . ASN C 1 136 ? -8.083  8.919   144.527 1.00 16.76  ? 136 ASN C O   1 
ATOM 3468 C CB  . ASN C 1 136 ? -4.911  8.827   144.954 1.00 16.76  ? 136 ASN C CB  1 
ATOM 3469 C CG  . ASN C 1 136 ? -3.622  8.228   145.482 1.00 16.76  ? 136 ASN C CG  1 
ATOM 3470 O OD1 . ASN C 1 136 ? -3.233  8.471   146.624 1.00 16.76  ? 136 ASN C OD1 1 
ATOM 3471 N ND2 . ASN C 1 136 ? -2.950  7.441   144.651 1.00 16.76  ? 136 ASN C ND2 1 
ATOM 3472 N N   . ALA C 1 137 ? -7.468  10.519  145.993 1.00 14.88  ? 137 ALA C N   1 
ATOM 3473 C CA  . ALA C 1 137 ? -8.513  11.438  145.571 1.00 14.88  ? 137 ALA C CA  1 
ATOM 3474 C C   . ALA C 1 137 ? -8.235  11.963  144.161 1.00 14.88  ? 137 ALA C C   1 
ATOM 3475 O O   . ALA C 1 137 ? -7.096  12.321  143.846 1.00 14.88  ? 137 ALA C O   1 
ATOM 3476 C CB  . ALA C 1 137 ? -8.617  12.608  146.546 1.00 14.88  ? 137 ALA C CB  1 
ATOM 3477 N N   . PRO C 1 138 ? -9.246  12.016  143.291 1.00 15.57  ? 138 PRO C N   1 
ATOM 3478 C CA  . PRO C 1 138 ? -9.030  12.560  141.946 1.00 15.57  ? 138 PRO C CA  1 
ATOM 3479 C C   . PRO C 1 138 ? -8.595  14.019  141.988 1.00 15.57  ? 138 PRO C C   1 
ATOM 3480 O O   . PRO C 1 138 ? -9.130  14.822  142.754 1.00 15.57  ? 138 PRO C O   1 
ATOM 3481 C CB  . PRO C 1 138 ? -10.397 12.400  141.266 1.00 15.57  ? 138 PRO C CB  1 
ATOM 3482 C CG  . PRO C 1 138 ? -11.106 11.365  142.054 1.00 15.57  ? 138 PRO C CG  1 
ATOM 3483 C CD  . PRO C 1 138 ? -10.610 11.488  143.455 1.00 15.57  ? 138 PRO C CD  1 
ATOM 3484 N N   . ILE C 1 139 ? -7.612  14.358  141.156 1.00 16.13  ? 139 ILE C N   1 
ATOM 3485 C CA  . ILE C 1 139 ? -7.066  15.709  141.096 1.00 16.13  ? 139 ILE C CA  1 
ATOM 3486 C C   . ILE C 1 139 ? -6.903  16.111  139.636 1.00 16.13  ? 139 ILE C C   1 
ATOM 3487 O O   . ILE C 1 139 ? -6.507  15.296  138.797 1.00 16.13  ? 139 ILE C O   1 
ATOM 3488 C CB  . ILE C 1 139 ? -5.721  15.817  141.845 1.00 16.13  ? 139 ILE C CB  1 
ATOM 3489 C CG1 . ILE C 1 139 ? -5.345  17.287  142.045 1.00 16.13  ? 139 ILE C CG1 1 
ATOM 3490 C CG2 . ILE C 1 139 ? -4.621  15.086  141.088 1.00 16.13  ? 139 ILE C CG2 1 
ATOM 3491 C CD1 . ILE C 1 139 ? -4.238  17.505  143.047 1.00 16.13  ? 139 ILE C CD1 1 
ATOM 3492 N N   . LEU C 1 140 ? -7.214  17.370  139.337 1.00 15.71  ? 140 LEU C N   1 
ATOM 3493 C CA  . LEU C 1 140 ? -6.917  17.940  138.029 1.00 15.71  ? 140 LEU C CA  1 
ATOM 3494 C C   . LEU C 1 140 ? -5.434  18.270  137.919 1.00 15.71  ? 140 LEU C C   1 
ATOM 3495 O O   . LEU C 1 140 ? -4.820  18.754  138.875 1.00 15.71  ? 140 LEU C O   1 
ATOM 3496 C CB  . LEU C 1 140 ? -7.750  19.202  137.800 1.00 15.71  ? 140 LEU C CB  1 
ATOM 3497 C CG  . LEU C 1 140 ? -9.242  18.992  137.539 1.00 15.71  ? 140 LEU C CG  1 
ATOM 3498 C CD1 . LEU C 1 140 ? -10.018 20.258  137.858 1.00 15.71  ? 140 LEU C CD1 1 
ATOM 3499 C CD2 . LEU C 1 140 ? -9.489  18.561  136.104 1.00 15.71  ? 140 LEU C CD2 1 
ATOM 3500 N N   . SER C 1 141 ? -4.858  18.007  136.748 1.00 19.96  ? 141 SER C N   1 
ATOM 3501 C CA  . SER C 1 141 ? -3.436  18.238  136.541 1.00 19.96  ? 141 SER C CA  1 
ATOM 3502 C C   . SER C 1 141 ? -3.192  18.676  135.104 1.00 19.96  ? 141 SER C C   1 
ATOM 3503 O O   . SER C 1 141 ? -3.964  18.350  134.199 1.00 19.96  ? 141 SER C O   1 
ATOM 3504 C CB  . SER C 1 141 ? -2.616  16.982  136.853 1.00 19.96  ? 141 SER C CB  1 
ATOM 3505 O OG  . SER C 1 141 ? -1.230  17.222  136.684 1.00 19.96  ? 141 SER C OG  1 
ATOM 3506 N N   . THR C 1 142 ? -2.102  19.418  134.911 1.00 23.72  ? 142 THR C N   1 
ATOM 3507 C CA  . THR C 1 142 ? -1.730  19.949  133.607 1.00 23.72  ? 142 THR C CA  1 
ATOM 3508 C C   . THR C 1 142 ? -0.438  19.354  133.063 1.00 23.72  ? 142 THR C C   1 
ATOM 3509 O O   . THR C 1 142 ? -0.100  19.612  131.903 1.00 23.72  ? 142 THR C O   1 
ATOM 3510 C CB  . THR C 1 142 ? -1.594  21.479  133.674 1.00 23.72  ? 142 THR C CB  1 
ATOM 3511 O OG1 . THR C 1 142 ? -1.489  22.014  132.349 1.00 23.72  ? 142 THR C OG1 1 
ATOM 3512 C CG2 . THR C 1 142 ? -0.371  21.885  134.488 1.00 23.72  ? 142 THR C CG2 1 
ATOM 3513 N N   . LEU C 1 143 ? 0.290   18.580  133.863 1.00 29.75  ? 143 LEU C N   1 
ATOM 3514 C CA  . LEU C 1 143 ? 1.522   17.973  133.394 1.00 29.75  ? 143 LEU C CA  1 
ATOM 3515 C C   . LEU C 1 143 ? 1.231   16.824  132.428 1.00 29.75  ? 143 LEU C C   1 
ATOM 3516 O O   . LEU C 1 143 ? 0.222   16.130  132.562 1.00 29.75  ? 143 LEU C O   1 
ATOM 3517 C CB  . LEU C 1 143 ? 2.343   17.453  134.570 1.00 29.75  ? 143 LEU C CB  1 
ATOM 3518 C CG  . LEU C 1 143 ? 2.964   18.499  135.497 1.00 29.75  ? 143 LEU C CG  1 
ATOM 3519 C CD1 . LEU C 1 143 ? 3.693   17.815  136.640 1.00 29.75  ? 143 LEU C CD1 1 
ATOM 3520 C CD2 . LEU C 1 143 ? 3.915   19.414  134.735 1.00 29.75  ? 143 LEU C CD2 1 
ATOM 3521 N N   . PRO C 1 144 ? 2.104   16.605  131.445 1.00 37.72  ? 144 PRO C N   1 
ATOM 3522 C CA  . PRO C 1 144 ? 2.009   15.386  130.639 1.00 37.72  ? 144 PRO C CA  1 
ATOM 3523 C C   . PRO C 1 144 ? 2.277   14.142  131.471 1.00 37.72  ? 144 PRO C C   1 
ATOM 3524 O O   . PRO C 1 144 ? 2.978   14.180  132.486 1.00 37.72  ? 144 PRO C O   1 
ATOM 3525 C CB  . PRO C 1 144 ? 3.083   15.586  129.563 1.00 37.72  ? 144 PRO C CB  1 
ATOM 3526 C CG  . PRO C 1 144 ? 4.093   16.457  130.213 1.00 37.72  ? 144 PRO C CG  1 
ATOM 3527 C CD  . PRO C 1 144 ? 3.303   17.390  131.099 1.00 37.72  ? 144 PRO C CD  1 
ATOM 3528 N N   . GLU C 1 145 ? 1.705   13.022  131.024 1.00 46.86  ? 145 GLU C N   1 
ATOM 3529 C CA  . GLU C 1 145 ? 1.739   11.804  131.828 1.00 46.86  ? 145 GLU C CA  1 
ATOM 3530 C C   . GLU C 1 145 ? 3.142   11.219  131.911 1.00 46.86  ? 145 GLU C C   1 
ATOM 3531 O O   . GLU C 1 145 ? 3.479   10.568  132.907 1.00 46.86  ? 145 GLU C O   1 
ATOM 3532 C CB  . GLU C 1 145 ? 0.769   10.772  131.252 1.00 46.86  ? 145 GLU C CB  1 
ATOM 3533 C CG  . GLU C 1 145 ? 0.607   9.529   132.111 1.00 46.86  ? 145 GLU C CG  1 
ATOM 3534 C CD  . GLU C 1 145 ? -0.494  8.615   131.610 1.00 46.86  ? 145 GLU C CD  1 
ATOM 3535 O OE1 . GLU C 1 145 ? -1.613  9.109   131.361 1.00 46.86  ? 145 GLU C OE1 1 
ATOM 3536 O OE2 . GLU C 1 145 ? -0.240  7.401   131.464 1.00 46.86  ? 145 GLU C OE2 1 
ATOM 3537 N N   . THR C 1 146 ? 3.968   11.430  130.891 1.00 50.42  ? 146 THR C N   1 
ATOM 3538 C CA  . THR C 1 146 ? 5.339   10.937  130.911 1.00 50.42  ? 146 THR C CA  1 
ATOM 3539 C C   . THR C 1 146 ? 6.178   11.713  131.920 1.00 50.42  ? 146 THR C C   1 
ATOM 3540 O O   . THR C 1 146 ? 7.201   11.223  132.399 1.00 50.42  ? 146 THR C O   1 
ATOM 3541 C CB  . THR C 1 146 ? 5.999   11.040  129.522 1.00 50.42  ? 146 THR C CB  1 
ATOM 3542 O OG1 . THR C 1 146 ? 5.941   12.395  129.061 1.00 50.42  ? 146 THR C OG1 1 
ATOM 3543 C CG2 . THR C 1 146 ? 5.297   10.130  128.525 1.00 50.42  ? 146 THR C CG2 1 
ATOM 3544 N N   . MET D 1 1   ? -6.750  44.066  141.502 1.00 18.95  ? 1   MET D N   1 
ATOM 3545 C CA  . MET D 1 1   ? -7.467  43.705  140.246 1.00 18.95  ? 1   MET D CA  1 
ATOM 3546 C C   . MET D 1 1   ? -8.408  44.844  139.853 1.00 18.95  ? 1   MET D C   1 
ATOM 3547 O O   . MET D 1 1   ? -9.485  45.004  140.426 1.00 18.95  ? 1   MET D O   1 
ATOM 3548 C CB  . MET D 1 1   ? -8.232  42.394  140.424 1.00 18.95  ? 1   MET D CB  1 
ATOM 3549 C CG  . MET D 1 1   ? -8.889  41.886  139.156 1.00 18.95  ? 1   MET D CG  1 
ATOM 3550 S SD  . MET D 1 1   ? -7.703  41.465  137.865 1.00 18.95  ? 1   MET D SD  1 
ATOM 3551 C CE  . MET D 1 1   ? -6.997  39.959  138.523 1.00 18.95  ? 1   MET D CE  1 
ATOM 3552 N N   . ASP D 1 2   ? -7.984  45.629  138.862 1.00 20.07  ? 2   ASP D N   1 
ATOM 3553 C CA  . ASP D 1 2   ? -8.732  46.786  138.371 1.00 20.07  ? 2   ASP D CA  1 
ATOM 3554 C C   . ASP D 1 2   ? -9.563  46.377  137.157 1.00 20.07  ? 2   ASP D C   1 
ATOM 3555 O O   . ASP D 1 2   ? -9.196  46.608  136.006 1.00 20.07  ? 2   ASP D O   1 
ATOM 3556 C CB  . ASP D 1 2   ? -7.779  47.935  138.046 1.00 20.07  ? 2   ASP D CB  1 
ATOM 3557 C CG  . ASP D 1 2   ? -8.485  49.273  137.968 1.00 20.07  ? 2   ASP D CG  1 
ATOM 3558 O OD1 . ASP D 1 2   ? -9.734  49.288  137.944 1.00 20.07  ? 2   ASP D OD1 1 
ATOM 3559 O OD2 . ASP D 1 2   ? -7.793  50.313  137.929 1.00 20.07  ? 2   ASP D OD2 1 
ATOM 3560 N N   . ILE D 1 3   ? -10.712 45.761  137.430 1.00 16.12  ? 3   ILE D N   1 
ATOM 3561 C CA  . ILE D 1 3   ? -11.721 45.495  136.409 1.00 16.12  ? 3   ILE D CA  1 
ATOM 3562 C C   . ILE D 1 3   ? -12.625 46.710  136.268 1.00 16.12  ? 3   ILE D C   1 
ATOM 3563 O O   . ILE D 1 3   ? -13.056 47.309  137.260 1.00 16.12  ? 3   ILE D O   1 
ATOM 3564 C CB  . ILE D 1 3   ? -12.548 44.241  136.750 1.00 16.12  ? 3   ILE D CB  1 
ATOM 3565 C CG1 . ILE D 1 3   ? -11.643 43.091  137.187 1.00 16.12  ? 3   ILE D CG1 1 
ATOM 3566 C CG2 . ILE D 1 3   ? -13.407 43.833  135.559 1.00 16.12  ? 3   ILE D CG2 1 
ATOM 3567 C CD1 . ILE D 1 3   ? -10.584 42.712  136.173 1.00 16.12  ? 3   ILE D CD1 1 
ATOM 3568 N N   . ASP D 1 4   ? -12.910 47.075  135.019 1.00 14.56  ? 4   ASP D N   1 
ATOM 3569 C CA  . ASP D 1 4   ? -13.988 47.994  134.692 1.00 14.56  ? 4   ASP D CA  1 
ATOM 3570 C C   . ASP D 1 4   ? -15.078 47.216  133.967 1.00 14.56  ? 4   ASP D C   1 
ATOM 3571 O O   . ASP D 1 4   ? -14.800 46.611  132.921 1.00 14.56  ? 4   ASP D O   1 
ATOM 3572 C CB  . ASP D 1 4   ? -13.460 49.136  133.817 1.00 14.56  ? 4   ASP D CB  1 
ATOM 3573 C CG  . ASP D 1 4   ? -14.557 50.063  133.302 1.00 14.56  ? 4   ASP D CG  1 
ATOM 3574 O OD1 . ASP D 1 4   ? -15.727 49.648  133.180 1.00 14.56  ? 4   ASP D OD1 1 
ATOM 3575 O OD2 . ASP D 1 4   ? -14.231 51.228  132.992 1.00 14.56  ? 4   ASP D OD2 1 
ATOM 3576 N N   . PRO D 1 5   ? -16.314 47.189  134.475 1.00 13.33  ? 5   PRO D N   1 
ATOM 3577 C CA  . PRO D 1 5   ? -17.347 46.339  133.853 1.00 13.33  ? 5   PRO D CA  1 
ATOM 3578 C C   . PRO D 1 5   ? -17.637 46.682  132.402 1.00 13.33  ? 5   PRO D C   1 
ATOM 3579 O O   . PRO D 1 5   ? -18.147 45.828  131.668 1.00 13.33  ? 5   PRO D O   1 
ATOM 3580 C CB  . PRO D 1 5   ? -18.585 46.577  134.732 1.00 13.33  ? 5   PRO D CB  1 
ATOM 3581 C CG  . PRO D 1 5   ? -18.310 47.822  135.495 1.00 13.33  ? 5   PRO D CG  1 
ATOM 3582 C CD  . PRO D 1 5   ? -16.829 47.926  135.639 1.00 13.33  ? 5   PRO D CD  1 
ATOM 3583 N N   . TYR D 1 6   ? -17.328 47.902  131.966 1.00 12.64  ? 6   TYR D N   1 
ATOM 3584 C CA  . TYR D 1 6   ? -17.699 48.382  130.642 1.00 12.64  ? 6   TYR D CA  1 
ATOM 3585 C C   . TYR D 1 6   ? -16.576 48.269  129.622 1.00 12.64  ? 6   TYR D C   1 
ATOM 3586 O O   . TYR D 1 6   ? -16.842 48.373  128.420 1.00 12.64  ? 6   TYR D O   1 
ATOM 3587 C CB  . TYR D 1 6   ? -18.157 49.840  130.736 1.00 12.64  ? 6   TYR D CB  1 
ATOM 3588 C CG  . TYR D 1 6   ? -19.183 50.065  131.823 1.00 12.64  ? 6   TYR D CG  1 
ATOM 3589 C CD1 . TYR D 1 6   ? -20.405 49.407  131.798 1.00 12.64  ? 6   TYR D CD1 1 
ATOM 3590 C CD2 . TYR D 1 6   ? -18.928 50.930  132.877 1.00 12.64  ? 6   TYR D CD2 1 
ATOM 3591 C CE1 . TYR D 1 6   ? -21.363 49.647  132.758 1.00 12.64  ? 6   TYR D CE1 1 
ATOM 3592 C CE2 . TYR D 1 6   ? -19.865 51.145  133.867 1.00 12.64  ? 6   TYR D CE2 1 
ATOM 3593 C CZ  . TYR D 1 6   ? -21.082 50.498  133.803 1.00 12.64  ? 6   TYR D CZ  1 
ATOM 3594 O OH  . TYR D 1 6   ? -21.992 50.660  134.819 1.00 12.64  ? 6   TYR D OH  1 
ATOM 3595 N N   . LYS D 1 7   ? -15.337 48.059  130.070 1.00 14.45  ? 7   LYS D N   1 
ATOM 3596 C CA  . LYS D 1 7   ? -14.187 48.140  129.175 1.00 14.45  ? 7   LYS D CA  1 
ATOM 3597 C C   . LYS D 1 7   ? -14.317 47.177  128.000 1.00 14.45  ? 7   LYS D C   1 
ATOM 3598 O O   . LYS D 1 7   ? -14.035 47.549  126.855 1.00 14.45  ? 7   LYS D O   1 
ATOM 3599 C CB  . LYS D 1 7   ? -12.909 47.856  129.964 1.00 14.45  ? 7   LYS D CB  1 
ATOM 3600 C CG  . LYS D 1 7   ? -11.626 48.033  129.175 1.00 14.45  ? 7   LYS D CG  1 
ATOM 3601 C CD  . LYS D 1 7   ? -10.410 47.842  130.065 1.00 14.45  ? 7   LYS D CD  1 
ATOM 3602 C CE  . LYS D 1 7   ? -9.122  47.865  129.267 1.00 14.45  ? 7   LYS D CE  1 
ATOM 3603 N NZ  . LYS D 1 7   ? -8.860  49.195  128.659 1.00 14.45  ? 7   LYS D NZ  1 
ATOM 3604 N N   . GLU D 1 8   ? -14.742 45.938  128.254 1.00 14.41  ? 8   GLU D N   1 
ATOM 3605 C CA  . GLU D 1 8   ? -14.909 44.984  127.164 1.00 14.41  ? 8   GLU D CA  1 
ATOM 3606 C C   . GLU D 1 8   ? -16.050 45.342  126.221 1.00 14.41  ? 8   GLU D C   1 
ATOM 3607 O O   . GLU D 1 8   ? -16.127 44.769  125.131 1.00 14.41  ? 8   GLU D O   1 
ATOM 3608 C CB  . GLU D 1 8   ? -15.139 43.575  127.719 1.00 14.41  ? 8   GLU D CB  1 
ATOM 3609 C CG  . GLU D 1 8   ? -16.463 43.392  128.448 1.00 14.41  ? 8   GLU D CG  1 
ATOM 3610 C CD  . GLU D 1 8   ? -16.639 41.989  128.996 1.00 14.41  ? 8   GLU D CD  1 
ATOM 3611 O OE1 . GLU D 1 8   ? -15.751 41.143  128.766 1.00 14.41  ? 8   GLU D OE1 1 
ATOM 3612 O OE2 . GLU D 1 8   ? -17.660 41.735  129.666 1.00 14.41  ? 8   GLU D OE2 1 
ATOM 3613 N N   . PHE D 1 9   ? -16.926 46.269  126.600 1.00 12.74  ? 9   PHE D N   1 
ATOM 3614 C CA  . PHE D 1 9   ? -17.963 46.780  125.714 1.00 12.74  ? 9   PHE D CA  1 
ATOM 3615 C C   . PHE D 1 9   ? -17.596 48.125  125.096 1.00 12.74  ? 9   PHE D C   1 
ATOM 3616 O O   . PHE D 1 9   ? -18.452 48.766  124.480 1.00 12.74  ? 9   PHE D O   1 
ATOM 3617 C CB  . PHE D 1 9   ? -19.290 46.883  126.467 1.00 12.74  ? 9   PHE D CB  1 
ATOM 3618 C CG  . PHE D 1 9   ? -19.718 45.594  127.110 1.00 12.74  ? 9   PHE D CG  1 
ATOM 3619 C CD1 . PHE D 1 9   ? -20.363 44.619  126.368 1.00 12.74  ? 9   PHE D CD1 1 
ATOM 3620 C CD2 . PHE D 1 9   ? -19.454 45.344  128.445 1.00 12.74  ? 9   PHE D CD2 1 
ATOM 3621 C CE1 . PHE D 1 9   ? -20.750 43.427  126.948 1.00 12.74  ? 9   PHE D CE1 1 
ATOM 3622 C CE2 . PHE D 1 9   ? -19.844 44.156  129.031 1.00 12.74  ? 9   PHE D CE2 1 
ATOM 3623 C CZ  . PHE D 1 9   ? -20.495 43.198  128.282 1.00 12.74  ? 9   PHE D CZ  1 
ATOM 3624 N N   . GLY D 1 10  ? -16.350 48.566  125.253 1.00 13.69  ? 10  GLY D N   1 
ATOM 3625 C CA  . GLY D 1 10  ? -15.887 49.803  124.663 1.00 13.69  ? 10  GLY D CA  1 
ATOM 3626 C C   . GLY D 1 10  ? -16.394 51.070  125.314 1.00 13.69  ? 10  GLY D C   1 
ATOM 3627 O O   . GLY D 1 10  ? -16.042 52.162  124.853 1.00 13.69  ? 10  GLY D O   1 
ATOM 3628 N N   . ALA D 1 11  ? -17.209 50.969  126.357 1.00 12.95  ? 11  ALA D N   1 
ATOM 3629 C CA  . ALA D 1 11  ? -17.514 52.097  127.220 1.00 12.95  ? 11  ALA D CA  1 
ATOM 3630 C C   . ALA D 1 11  ? -16.536 52.162  128.392 1.00 12.95  ? 11  ALA D C   1 
ATOM 3631 O O   . ALA D 1 11  ? -15.683 51.294  128.579 1.00 12.95  ? 11  ALA D O   1 
ATOM 3632 C CB  . ALA D 1 11  ? -18.956 52.008  127.722 1.00 12.95  ? 11  ALA D CB  1 
ATOM 3633 N N   . THR D 1 12  ? -16.671 53.222  129.187 1.00 14.05  ? 12  THR D N   1 
ATOM 3634 C CA  . THR D 1 12  ? -15.860 53.426  130.378 1.00 14.05  ? 12  THR D CA  1 
ATOM 3635 C C   . THR D 1 12  ? -16.756 53.965  131.482 1.00 14.05  ? 12  THR D C   1 
ATOM 3636 O O   . THR D 1 12  ? -17.843 54.487  131.228 1.00 14.05  ? 12  THR D O   1 
ATOM 3637 C CB  . THR D 1 12  ? -14.687 54.384  130.124 1.00 14.05  ? 12  THR D CB  1 
ATOM 3638 O OG1 . THR D 1 12  ? -15.173 55.728  130.014 1.00 14.05  ? 12  THR D OG1 1 
ATOM 3639 C CG2 . THR D 1 12  ? -13.945 54.004  128.851 1.00 14.05  ? 12  THR D CG2 1 
ATOM 3640 N N   . VAL D 1 13  ? -16.283 53.838  132.724 1.00 14.17  ? 13  VAL D N   1 
ATOM 3641 C CA  . VAL D 1 13  ? -17.022 54.397  133.852 1.00 14.17  ? 13  VAL D CA  1 
ATOM 3642 C C   . VAL D 1 13  ? -17.133 55.913  133.757 1.00 14.17  ? 13  VAL D C   1 
ATOM 3643 O O   . VAL D 1 13  ? -18.120 56.494  134.216 1.00 14.17  ? 13  VAL D O   1 
ATOM 3644 C CB  . VAL D 1 13  ? -16.357 53.972  135.178 1.00 14.17  ? 13  VAL D CB  1 
ATOM 3645 C CG1 . VAL D 1 13  ? -17.043 54.641  136.358 1.00 14.17  ? 13  VAL D CG1 1 
ATOM 3646 C CG2 . VAL D 1 13  ? -16.396 52.461  135.329 1.00 14.17  ? 13  VAL D CG2 1 
ATOM 3647 N N   . GLU D 1 14  ? -16.130 56.581  133.186 1.00 15.73  ? 14  GLU D N   1 
ATOM 3648 C CA  . GLU D 1 14  ? -16.211 58.029  132.996 1.00 15.73  ? 14  GLU D CA  1 
ATOM 3649 C C   . GLU D 1 14  ? -17.272 58.418  131.967 1.00 15.73  ? 14  GLU D C   1 
ATOM 3650 O O   . GLU D 1 14  ? -18.032 59.378  132.170 1.00 15.73  ? 14  GLU D O   1 
ATOM 3651 C CB  . GLU D 1 14  ? -14.844 58.586  132.588 1.00 15.73  ? 14  GLU D CB  1 
ATOM 3652 C CG  . GLU D 1 14  ? -13.711 58.303  133.576 1.00 15.73  ? 14  GLU D CG  1 
ATOM 3653 C CD  . GLU D 1 14  ? -13.173 56.886  133.491 1.00 15.73  ? 14  GLU D CD  1 
ATOM 3654 O OE1 . GLU D 1 14  ? -12.899 56.288  134.551 1.00 15.73  ? 14  GLU D OE1 1 
ATOM 3655 O OE2 . GLU D 1 14  ? -13.024 56.373  132.362 1.00 15.73  ? 14  GLU D OE2 1 
ATOM 3656 N N   . LEU D 1 15  ? -17.366 57.665  130.871 1.00 13.60  ? 15  LEU D N   1 
ATOM 3657 C CA  . LEU D 1 15  ? -18.382 57.965  129.868 1.00 13.60  ? 15  LEU D CA  1 
ATOM 3658 C C   . LEU D 1 15  ? -19.786 57.833  130.445 1.00 13.60  ? 15  LEU D C   1 
ATOM 3659 O O   . LEU D 1 15  ? -20.636 58.700  130.228 1.00 13.60  ? 15  LEU D O   1 
ATOM 3660 C CB  . LEU D 1 15  ? -18.194 57.044  128.661 1.00 13.60  ? 15  LEU D CB  1 
ATOM 3661 C CG  . LEU D 1 15  ? -19.103 57.279  127.455 1.00 13.60  ? 15  LEU D CG  1 
ATOM 3662 C CD1 . LEU D 1 15  ? -18.724 58.569  126.751 1.00 13.60  ? 15  LEU D CD1 1 
ATOM 3663 C CD2 . LEU D 1 15  ? -19.020 56.104  126.497 1.00 13.60  ? 15  LEU D CD2 1 
ATOM 3664 N N   . LEU D 1 16  ? -20.057 56.750  131.175 1.00 13.18  ? 16  LEU D N   1 
ATOM 3665 C CA  . LEU D 1 16  ? -21.353 56.650  131.841 1.00 13.18  ? 16  LEU D CA  1 
ATOM 3666 C C   . LEU D 1 16  ? -21.505 57.690  132.948 1.00 13.18  ? 16  LEU D C   1 
ATOM 3667 O O   . LEU D 1 16  ? -22.621 58.147  133.217 1.00 13.18  ? 16  LEU D O   1 
ATOM 3668 C CB  . LEU D 1 16  ? -21.566 55.244  132.399 1.00 13.18  ? 16  LEU D CB  1 
ATOM 3669 C CG  . LEU D 1 16  ? -21.825 54.143  131.366 1.00 13.18  ? 16  LEU D CG  1 
ATOM 3670 C CD1 . LEU D 1 16  ? -20.548 53.676  130.684 1.00 13.18  ? 16  LEU D CD1 1 
ATOM 3671 C CD2 . LEU D 1 16  ? -22.549 52.980  132.016 1.00 13.18  ? 16  LEU D CD2 1 
ATOM 3672 N N   . SER D 1 17  ? -20.401 58.066  133.601 1.00 14.35  ? 17  SER D N   1 
ATOM 3673 C CA  . SER D 1 17  ? -20.396 59.206  134.513 1.00 14.35  ? 17  SER D CA  1 
ATOM 3674 C C   . SER D 1 17  ? -20.877 60.487  133.853 1.00 14.35  ? 17  SER D C   1 
ATOM 3675 O O   . SER D 1 17  ? -21.339 61.390  134.558 1.00 14.35  ? 17  SER D O   1 
ATOM 3676 C CB  . SER D 1 17  ? -18.996 59.415  135.097 1.00 14.35  ? 17  SER D CB  1 
ATOM 3677 O OG  . SER D 1 17  ? -18.564 58.269  135.811 1.00 14.35  ? 17  SER D OG  1 
ATOM 3678 N N   . PHE D 1 18  ? -20.774 60.603  132.527 1.00 13.95  ? 18  PHE D N   1 
ATOM 3679 C CA  . PHE D 1 18  ? -21.424 61.735  131.871 1.00 13.95  ? 18  PHE D CA  1 
ATOM 3680 C C   . PHE D 1 18  ? -22.905 61.819  132.226 1.00 13.95  ? 18  PHE D C   1 
ATOM 3681 O O   . PHE D 1 18  ? -23.452 62.922  132.345 1.00 13.95  ? 18  PHE D O   1 
ATOM 3682 C CB  . PHE D 1 18  ? -21.285 61.649  130.347 1.00 13.95  ? 18  PHE D CB  1 
ATOM 3683 C CG  . PHE D 1 18  ? -19.889 61.879  129.831 1.00 13.95  ? 18  PHE D CG  1 
ATOM 3684 C CD1 . PHE D 1 18  ? -18.848 62.213  130.683 1.00 13.95  ? 18  PHE D CD1 1 
ATOM 3685 C CD2 . PHE D 1 18  ? -19.627 61.781  128.475 1.00 13.95  ? 18  PHE D CD2 1 
ATOM 3686 C CE1 . PHE D 1 18  ? -17.574 62.429  130.191 1.00 13.95  ? 18  PHE D CE1 1 
ATOM 3687 C CE2 . PHE D 1 18  ? -18.358 61.993  127.981 1.00 13.95  ? 18  PHE D CE2 1 
ATOM 3688 C CZ  . PHE D 1 18  ? -17.330 62.317  128.839 1.00 13.95  ? 18  PHE D CZ  1 
ATOM 3689 N N   . LEU D 1 19  ? -23.572 60.680  132.395 1.00 12.91  ? 19  LEU D N   1 
ATOM 3690 C CA  . LEU D 1 19  ? -24.943 60.680  132.888 1.00 12.91  ? 19  LEU D CA  1 
ATOM 3691 C C   . LEU D 1 19  ? -24.988 61.020  134.379 1.00 12.91  ? 19  LEU D C   1 
ATOM 3692 O O   . LEU D 1 19  ? -24.185 60.499  135.159 1.00 12.91  ? 19  LEU D O   1 
ATOM 3693 C CB  . LEU D 1 19  ? -25.600 59.319  132.659 1.00 12.91  ? 19  LEU D CB  1 
ATOM 3694 C CG  . LEU D 1 19  ? -25.655 58.806  131.221 1.00 12.91  ? 19  LEU D CG  1 
ATOM 3695 C CD1 . LEU D 1 19  ? -26.218 57.395  131.188 1.00 12.91  ? 19  LEU D CD1 1 
ATOM 3696 C CD2 . LEU D 1 19  ? -26.488 59.733  130.353 1.00 12.91  ? 19  LEU D CD2 1 
ATOM 3697 N N   . PRO D 1 20  ? -25.910 61.884  134.807 1.00 13.68  ? 20  PRO D N   1 
ATOM 3698 C CA  . PRO D 1 20  ? -26.025 62.178  136.239 1.00 13.68  ? 20  PRO D CA  1 
ATOM 3699 C C   . PRO D 1 20  ? -26.636 61.008  136.997 1.00 13.68  ? 20  PRO D C   1 
ATOM 3700 O O   . PRO D 1 20  ? -27.387 60.200  136.449 1.00 13.68  ? 20  PRO D O   1 
ATOM 3701 C CB  . PRO D 1 20  ? -26.931 63.411  136.273 1.00 13.68  ? 20  PRO D CB  1 
ATOM 3702 C CG  . PRO D 1 20  ? -27.810 63.246  135.092 1.00 13.68  ? 20  PRO D CG  1 
ATOM 3703 C CD  . PRO D 1 20  ? -26.965 62.563  134.032 1.00 13.68  ? 20  PRO D CD  1 
ATOM 3704 N N   . SER D 1 21  ? -26.295 60.926  138.287 1.00 15.31  ? 21  SER D N   1 
ATOM 3705 C CA  . SER D 1 21  ? -26.673 59.763  139.087 1.00 15.31  ? 21  SER D CA  1 
ATOM 3706 C C   . SER D 1 21  ? -28.184 59.603  139.219 1.00 15.31  ? 21  SER D C   1 
ATOM 3707 O O   . SER D 1 21  ? -28.671 58.476  139.367 1.00 15.31  ? 21  SER D O   1 
ATOM 3708 C CB  . SER D 1 21  ? -26.040 59.861  140.473 1.00 15.31  ? 21  SER D CB  1 
ATOM 3709 O OG  . SER D 1 21  ? -24.627 59.812  140.390 1.00 15.31  ? 21  SER D OG  1 
ATOM 3710 N N   . ASP D 1 22  ? -28.943 60.696  139.171 1.00 15.25  ? 22  ASP D N   1 
ATOM 3711 C CA  . ASP D 1 22  ? -30.398 60.607  139.235 1.00 15.25  ? 22  ASP D CA  1 
ATOM 3712 C C   . ASP D 1 22  ? -31.049 60.342  137.882 1.00 15.25  ? 22  ASP D C   1 
ATOM 3713 O O   . ASP D 1 22  ? -32.281 60.302  137.804 1.00 15.25  ? 22  ASP D O   1 
ATOM 3714 C CB  . ASP D 1 22  ? -30.971 61.895  139.836 1.00 15.25  ? 22  ASP D CB  1 
ATOM 3715 C CG  . ASP D 1 22  ? -30.666 63.119  138.997 1.00 15.25  ? 22  ASP D CG  1 
ATOM 3716 O OD1 . ASP D 1 22  ? -29.563 63.185  138.416 1.00 15.25  ? 22  ASP D OD1 1 
ATOM 3717 O OD2 . ASP D 1 22  ? -31.529 64.017  138.921 1.00 15.25  ? 22  ASP D OD2 1 
ATOM 3718 N N   . PHE D 1 23  ? -30.260 60.159  136.824 1.00 12.73  ? 23  PHE D N   1 
ATOM 3719 C CA  . PHE D 1 23  ? -30.818 59.817  135.519 1.00 12.73  ? 23  PHE D CA  1 
ATOM 3720 C C   . PHE D 1 23  ? -31.436 58.422  135.505 1.00 12.73  ? 23  PHE D C   1 
ATOM 3721 O O   . PHE D 1 23  ? -32.513 58.221  134.931 1.00 12.73  ? 23  PHE D O   1 
ATOM 3722 C CB  . PHE D 1 23  ? -29.728 59.928  134.453 1.00 12.73  ? 23  PHE D CB  1 
ATOM 3723 C CG  . PHE D 1 23  ? -30.157 59.467  133.092 1.00 12.73  ? 23  PHE D CG  1 
ATOM 3724 C CD1 . PHE D 1 23  ? -30.858 60.312  132.249 1.00 12.73  ? 23  PHE D CD1 1 
ATOM 3725 C CD2 . PHE D 1 23  ? -29.858 58.187  132.656 1.00 12.73  ? 23  PHE D CD2 1 
ATOM 3726 C CE1 . PHE D 1 23  ? -31.252 59.888  130.995 1.00 12.73  ? 23  PHE D CE1 1 
ATOM 3727 C CE2 . PHE D 1 23  ? -30.248 57.760  131.403 1.00 12.73  ? 23  PHE D CE2 1 
ATOM 3728 C CZ  . PHE D 1 23  ? -30.943 58.612  130.570 1.00 12.73  ? 23  PHE D CZ  1 
ATOM 3729 N N   . PHE D 1 24  ? -30.771 57.451  136.121 1.00 12.50  ? 24  PHE D N   1 
ATOM 3730 C CA  . PHE D 1 24  ? -31.125 56.052  135.909 1.00 12.50  ? 24  PHE D CA  1 
ATOM 3731 C C   . PHE D 1 24  ? -32.473 55.709  136.548 1.00 12.50  ? 24  PHE D C   1 
ATOM 3732 O O   . PHE D 1 24  ? -32.762 56.145  137.666 1.00 12.50  ? 24  PHE D O   1 
ATOM 3733 C CB  . PHE D 1 24  ? -30.020 55.166  136.471 1.00 12.50  ? 24  PHE D CB  1 
ATOM 3734 C CG  . PHE D 1 24  ? -28.677 55.449  135.866 1.00 12.50  ? 24  PHE D CG  1 
ATOM 3735 C CD1 . PHE D 1 24  ? -28.337 54.940  134.626 1.00 12.50  ? 24  PHE D CD1 1 
ATOM 3736 C CD2 . PHE D 1 24  ? -27.761 56.246  136.531 1.00 12.50  ? 24  PHE D CD2 1 
ATOM 3737 C CE1 . PHE D 1 24  ? -27.105 55.208  134.067 1.00 12.50  ? 24  PHE D CE1 1 
ATOM 3738 C CE2 . PHE D 1 24  ? -26.526 56.514  135.979 1.00 12.50  ? 24  PHE D CE2 1 
ATOM 3739 C CZ  . PHE D 1 24  ? -26.201 56.002  134.742 1.00 12.50  ? 24  PHE D CZ  1 
ATOM 3740 N N   . PRO D 1 25  ? -33.320 54.935  135.860 1.00 13.10  ? 25  PRO D N   1 
ATOM 3741 C CA  . PRO D 1 25  ? -34.596 54.504  136.449 1.00 13.10  ? 25  PRO D CA  1 
ATOM 3742 C C   . PRO D 1 25  ? -34.423 53.671  137.712 1.00 13.10  ? 25  PRO D C   1 
ATOM 3743 O O   . PRO D 1 25  ? -33.336 53.216  138.070 1.00 13.10  ? 25  PRO D O   1 
ATOM 3744 C CB  . PRO D 1 25  ? -35.248 53.681  135.330 1.00 13.10  ? 25  PRO D CB  1 
ATOM 3745 C CG  . PRO D 1 25  ? -34.606 54.155  134.086 1.00 13.10  ? 25  PRO D CG  1 
ATOM 3746 C CD  . PRO D 1 25  ? -33.193 54.471  134.468 1.00 13.10  ? 25  PRO D CD  1 
ATOM 3747 N N   . SER D 1 26  ? -35.553 53.478  138.394 1.00 14.97  ? 26  SER D N   1 
ATOM 3748 C CA  . SER D 1 26  ? -35.626 52.601  139.557 1.00 14.97  ? 26  SER D CA  1 
ATOM 3749 C C   . SER D 1 26  ? -35.243 51.167  139.202 1.00 14.97  ? 26  SER D C   1 
ATOM 3750 O O   . SER D 1 26  ? -35.378 50.723  138.057 1.00 14.97  ? 26  SER D O   1 
ATOM 3751 C CB  . SER D 1 26  ? -37.034 52.629  140.151 1.00 14.97  ? 26  SER D CB  1 
ATOM 3752 O OG  . SER D 1 26  ? -37.884 51.701  139.501 1.00 14.97  ? 26  SER D OG  1 
ATOM 3753 N N   . VAL D 1 27  ? -34.753 50.440  140.209 1.00 14.72  ? 27  VAL D N   1 
ATOM 3754 C CA  . VAL D 1 27  ? -34.465 49.014  140.057 1.00 14.72  ? 27  VAL D CA  1 
ATOM 3755 C C   . VAL D 1 27  ? -35.707 48.255  139.601 1.00 14.72  ? 27  VAL D C   1 
ATOM 3756 O O   . VAL D 1 27  ? -35.634 47.376  138.736 1.00 14.72  ? 27  VAL D O   1 
ATOM 3757 C CB  . VAL D 1 27  ? -33.919 48.434  141.376 1.00 14.72  ? 27  VAL D CB  1 
ATOM 3758 C CG1 . VAL D 1 27  ? -33.734 46.925  141.266 1.00 14.72  ? 27  VAL D CG1 1 
ATOM 3759 C CG2 . VAL D 1 27  ? -32.613 49.100  141.756 1.00 14.72  ? 27  VAL D CG2 1 
ATOM 3760 N N   . ARG D 1 28  ? -36.847 48.573  140.196 1.00 16.91  ? 28  ARG D N   1 
ATOM 3761 C CA  . ARG D 1 28  ? -38.088 47.863  139.816 1.00 16.91  ? 28  ARG D CA  1 
ATOM 3762 C C   . ARG D 1 28  ? -38.302 48.044  138.312 1.00 16.91  ? 28  ARG D C   1 
ATOM 3763 O O   . ARG D 1 28  ? -38.485 47.027  137.634 1.00 16.91  ? 28  ARG D O   1 
ATOM 3764 C CB  . ARG D 1 28  ? -39.260 48.382  140.647 1.00 16.91  ? 28  ARG D CB  1 
ATOM 3765 C CG  . ARG D 1 28  ? -40.498 47.497  140.598 1.00 16.91  ? 28  ARG D CG  1 
ATOM 3766 C CD  . ARG D 1 28  ? -40.155 46.053  140.898 1.00 16.91  ? 28  ARG D CD  1 
ATOM 3767 N NE  . ARG D 1 28  ? -39.852 45.305  139.688 1.00 16.91  ? 28  ARG D NE  1 
ATOM 3768 C CZ  . ARG D 1 28  ? -39.396 44.060  139.670 1.00 16.91  ? 28  ARG D CZ  1 
ATOM 3769 N NH1 . ARG D 1 28  ? -39.175 43.420  140.804 1.00 16.91  ? 28  ARG D NH1 1 
ATOM 3770 N NH2 . ARG D 1 28  ? -39.156 43.460  138.517 1.00 16.91  ? 28  ARG D NH2 1 
ATOM 3771 N N   . ASP D 1 29  ? -38.262 49.278  137.807 1.00 15.55  ? 29  ASP D N   1 
ATOM 3772 C CA  . ASP D 1 29  ? -38.538 49.512  136.392 1.00 15.55  ? 29  ASP D CA  1 
ATOM 3773 C C   . ASP D 1 29  ? -37.584 48.750  135.481 1.00 15.55  ? 29  ASP D C   1 
ATOM 3774 O O   . ASP D 1 29  ? -38.012 48.141  134.491 1.00 15.55  ? 29  ASP D O   1 
ATOM 3775 C CB  . ASP D 1 29  ? -38.466 51.009  136.092 1.00 15.55  ? 29  ASP D CB  1 
ATOM 3776 C CG  . ASP D 1 29  ? -39.601 51.787  136.723 1.00 15.55  ? 29  ASP D CG  1 
ATOM 3777 O OD1 . ASP D 1 29  ? -40.417 51.174  137.442 1.00 15.55  ? 29  ASP D OD1 1 
ATOM 3778 O OD2 . ASP D 1 29  ? -39.678 53.013  136.501 1.00 15.55  ? 29  ASP D OD2 1 
ATOM 3779 N N   . LEU D 1 30  ? -36.294 48.731  135.820 1.00 13.54  ? 30  LEU D N   1 
ATOM 3780 C CA  . LEU D 1 30  ? -35.320 48.026  134.992 1.00 13.54  ? 30  LEU D CA  1 
ATOM 3781 C C   . LEU D 1 30  ? -35.520 46.516  135.038 1.00 13.54  ? 30  LEU D C   1 
ATOM 3782 O O   . LEU D 1 30  ? -35.450 45.847  134.000 1.00 13.54  ? 30  LEU D O   1 
ATOM 3783 C CB  . LEU D 1 30  ? -33.907 48.388  135.448 1.00 13.54  ? 30  LEU D CB  1 
ATOM 3784 C CG  . LEU D 1 30  ? -33.482 49.842  135.223 1.00 13.54  ? 30  LEU D CG  1 
ATOM 3785 C CD1 . LEU D 1 30  ? -32.184 50.134  135.951 1.00 13.54  ? 30  LEU D CD1 1 
ATOM 3786 C CD2 . LEU D 1 30  ? -33.334 50.142  133.741 1.00 13.54  ? 30  LEU D CD2 1 
ATOM 3787 N N   . LEU D 1 31  ? -35.761 45.961  136.224 1.00 14.64  ? 31  LEU D N   1 
ATOM 3788 C CA  . LEU D 1 31  ? -36.031 44.531  136.325 1.00 14.64  ? 31  LEU D CA  1 
ATOM 3789 C C   . LEU D 1 31  ? -37.329 44.138  135.626 1.00 14.64  ? 31  LEU D C   1 
ATOM 3790 O O   . LEU D 1 31  ? -37.395 43.079  134.991 1.00 14.64  ? 31  LEU D O   1 
ATOM 3791 C CB  . LEU D 1 31  ? -36.073 44.108  137.795 1.00 14.64  ? 31  LEU D CB  1 
ATOM 3792 C CG  . LEU D 1 31  ? -34.748 44.150  138.561 1.00 14.64  ? 31  LEU D CG  1 
ATOM 3793 C CD1 . LEU D 1 31  ? -34.965 43.753  140.010 1.00 14.64  ? 31  LEU D CD1 1 
ATOM 3794 C CD2 . LEU D 1 31  ? -33.708 43.249  137.915 1.00 14.64  ? 31  LEU D CD2 1 
ATOM 3795 N N   . ASP D 1 32  ? -38.367 44.975  135.705 1.00 15.67  ? 32  ASP D N   1 
ATOM 3796 C CA  . ASP D 1 32  ? -39.578 44.708  134.933 1.00 15.67  ? 32  ASP D CA  1 
ATOM 3797 C C   . ASP D 1 32  ? -39.322 44.728  133.430 1.00 15.67  ? 32  ASP D C   1 
ATOM 3798 O O   . ASP D 1 32  ? -39.797 43.845  132.703 1.00 15.67  ? 32  ASP D O   1 
ATOM 3799 C CB  . ASP D 1 32  ? -40.655 45.732  135.293 1.00 15.67  ? 32  ASP D CB  1 
ATOM 3800 C CG  . ASP D 1 32  ? -41.249 45.493  136.665 1.00 15.67  ? 32  ASP D CG  1 
ATOM 3801 O OD1 . ASP D 1 32  ? -41.468 44.318  137.022 1.00 15.67  ? 32  ASP D OD1 1 
ATOM 3802 O OD2 . ASP D 1 32  ? -41.506 46.482  137.383 1.00 15.67  ? 32  ASP D OD2 1 
ATOM 3803 N N   . THR D 1 33  ? -38.562 45.710  132.942 1.00 14.24  ? 33  THR D N   1 
ATOM 3804 C CA  . THR D 1 33  ? -38.246 45.757  131.516 1.00 14.24  ? 33  THR D CA  1 
ATOM 3805 C C   . THR D 1 33  ? -37.445 44.538  131.072 1.00 14.24  ? 33  THR D C   1 
ATOM 3806 O O   . THR D 1 33  ? -37.730 43.939  130.023 1.00 14.24  ? 33  THR D O   1 
ATOM 3807 C CB  . THR D 1 33  ? -37.473 47.037  131.199 1.00 14.24  ? 33  THR D CB  1 
ATOM 3808 O OG1 . THR D 1 33  ? -38.217 48.173  131.659 1.00 14.24  ? 33  THR D OG1 1 
ATOM 3809 C CG2 . THR D 1 33  ? -37.232 47.167  129.702 1.00 14.24  ? 33  THR D CG2 1 
ATOM 3810 N N   . ALA D 1 34  ? -36.433 44.160  131.854 1.00 14.70  ? 34  ALA D N   1 
ATOM 3811 C CA  . ALA D 1 34  ? -35.640 42.979  131.532 1.00 14.70  ? 34  ALA D CA  1 
ATOM 3812 C C   . ALA D 1 34  ? -36.472 41.705  131.553 1.00 14.70  ? 34  ALA D C   1 
ATOM 3813 O O   . ALA D 1 34  ? -36.404 40.904  130.617 1.00 14.70  ? 34  ALA D O   1 
ATOM 3814 C CB  . ALA D 1 34  ? -34.468 42.859  132.506 1.00 14.70  ? 34  ALA D CB  1 
ATOM 3815 N N   . SER D 1 35  ? -37.315 41.526  132.569 1.00 16.99  ? 35  SER D N   1 
ATOM 3816 C CA  . SER D 1 35  ? -38.192 40.362  132.585 1.00 16.99  ? 35  SER D CA  1 
ATOM 3817 C C   . SER D 1 35  ? -39.129 40.335  131.386 1.00 16.99  ? 35  SER D C   1 
ATOM 3818 O O   . SER D 1 35  ? -39.368 39.270  130.807 1.00 16.99  ? 35  SER D O   1 
ATOM 3819 C CB  . SER D 1 35  ? -38.994 40.339  133.886 1.00 16.99  ? 35  SER D CB  1 
ATOM 3820 O OG  . SER D 1 35  ? -39.831 39.200  133.947 1.00 16.99  ? 35  SER D OG  1 
ATOM 3821 N N   . ALA D 1 36  ? -39.671 41.486  130.991 1.00 14.60  ? 36  ALA D N   1 
ATOM 3822 C CA  . ALA D 1 36  ? -40.627 41.474  129.890 1.00 14.60  ? 36  ALA D CA  1 
ATOM 3823 C C   . ALA D 1 36  ? -39.957 41.151  128.558 1.00 14.60  ? 36  ALA D C   1 
ATOM 3824 O O   . ALA D 1 36  ? -40.404 40.256  127.829 1.00 14.60  ? 36  ALA D O   1 
ATOM 3825 C CB  . ALA D 1 36  ? -41.342 42.821  129.810 1.00 14.60  ? 36  ALA D CB  1 
ATOM 3826 N N   . LEU D 1 37  ? -38.888 41.871  128.217 1.00 14.98  ? 37  LEU D N   1 
ATOM 3827 C CA  . LEU D 1 37  ? -38.206 41.643  126.943 1.00 14.98  ? 37  LEU D CA  1 
ATOM 3828 C C   . LEU D 1 37  ? -37.319 40.393  126.923 1.00 14.98  ? 37  LEU D C   1 
ATOM 3829 O O   . LEU D 1 37  ? -37.526 39.478  126.119 1.00 14.98  ? 37  LEU D O   1 
ATOM 3830 C CB  . LEU D 1 37  ? -37.373 42.875  126.579 1.00 14.98  ? 37  LEU D CB  1 
ATOM 3831 C CG  . LEU D 1 37  ? -38.149 44.185  126.405 1.00 14.98  ? 37  LEU D CG  1 
ATOM 3832 C CD1 . LEU D 1 37  ? -37.196 45.331  126.113 1.00 14.98  ? 37  LEU D CD1 1 
ATOM 3833 C CD2 . LEU D 1 37  ? -39.203 44.071  125.313 1.00 14.98  ? 37  LEU D CD2 1 
ATOM 3834 N N   . TYR D 1 38  ? -36.328 40.314  127.798 1.00 15.08  ? 38  TYR D N   1 
ATOM 3835 C CA  . TYR D 1 38  ? -35.364 39.198  127.635 1.00 15.08  ? 38  TYR D CA  1 
ATOM 3836 C C   . TYR D 1 38  ? -35.438 38.127  128.726 1.00 15.08  ? 38  TYR D C   1 
ATOM 3837 O O   . TYR D 1 38  ? -34.378 37.586  129.035 1.00 15.08  ? 38  TYR D O   1 
ATOM 3838 C CB  . TYR D 1 38  ? -33.969 39.810  127.565 1.00 15.08  ? 38  TYR D CB  1 
ATOM 3839 C CG  . TYR D 1 38  ? -33.917 41.092  126.779 1.00 15.08  ? 38  TYR D CG  1 
ATOM 3840 C CD1 . TYR D 1 38  ? -33.860 41.076  125.397 1.00 15.08  ? 38  TYR D CD1 1 
ATOM 3841 C CD2 . TYR D 1 38  ? -33.948 42.320  127.413 1.00 15.08  ? 38  TYR D CD2 1 
ATOM 3842 C CE1 . TYR D 1 38  ? -33.822 42.248  124.663 1.00 15.08  ? 38  TYR D CE1 1 
ATOM 3843 C CE2 . TYR D 1 38  ? -33.911 43.503  126.696 1.00 15.08  ? 38  TYR D CE2 1 
ATOM 3844 C CZ  . TYR D 1 38  ? -33.849 43.466  125.316 1.00 15.08  ? 38  TYR D CZ  1 
ATOM 3845 O OH  . TYR D 1 38  ? -33.812 44.623  124.595 1.00 15.08  ? 38  TYR D OH  1 
ATOM 3846 N N   . ARG D 1 39  ? -36.609 37.767  129.236 1.00 17.83  ? 39  ARG D N   1 
ATOM 3847 C CA  . ARG D 1 39  ? -36.594 36.717  130.284 1.00 17.83  ? 39  ARG D CA  1 
ATOM 3848 C C   . ARG D 1 39  ? -36.314 35.371  129.640 1.00 17.83  ? 39  ARG D C   1 
ATOM 3849 O O   . ARG D 1 39  ? -35.566 34.579  130.222 1.00 17.83  ? 39  ARG D O   1 
ATOM 3850 C CB  . ARG D 1 39  ? -37.941 36.609  130.995 1.00 17.83  ? 39  ARG D CB  1 
ATOM 3851 C CG  . ARG D 1 39  ? -37.927 35.665  132.187 1.00 17.83  ? 39  ARG D CG  1 
ATOM 3852 C CD  . ARG D 1 39  ? -39.321 35.458  132.741 1.00 17.83  ? 39  ARG D CD  1 
ATOM 3853 N NE  . ARG D 1 39  ? -40.236 35.114  131.665 1.00 17.83  ? 39  ARG D NE  1 
ATOM 3854 C CZ  . ARG D 1 39  ? -40.404 33.888  131.186 1.00 17.83  ? 39  ARG D CZ  1 
ATOM 3855 N NH1 . ARG D 1 39  ? -39.713 32.879  131.691 1.00 17.83  ? 39  ARG D NH1 1 
ATOM 3856 N NH2 . ARG D 1 39  ? -41.259 33.673  130.202 1.00 17.83  ? 39  ARG D NH2 1 
ATOM 3857 N N   . GLU D 1 40  ? -36.885 35.133  128.470 1.00 18.84  ? 40  GLU D N   1 
ATOM 3858 C CA  . GLU D 1 40  ? -36.757 33.819  127.842 1.00 18.84  ? 40  GLU D CA  1 
ATOM 3859 C C   . GLU D 1 40  ? -35.367 33.576  127.256 1.00 18.84  ? 40  GLU D C   1 
ATOM 3860 O O   . GLU D 1 40  ? -34.893 32.435  127.250 1.00 18.84  ? 40  GLU D O   1 
ATOM 3861 C CB  . GLU D 1 40  ? -37.818 33.651  126.757 1.00 18.84  ? 40  GLU D CB  1 
ATOM 3862 C CG  . GLU D 1 40  ? -38.074 32.200  126.360 1.00 18.84  ? 40  GLU D CG  1 
ATOM 3863 C CD  . GLU D 1 40  ? -37.162 31.716  125.253 1.00 18.84  ? 40  GLU D CD  1 
ATOM 3864 O OE1 . GLU D 1 40  ? -36.711 32.553  124.441 1.00 18.84  ? 40  GLU D OE1 1 
ATOM 3865 O OE2 . GLU D 1 40  ? -36.906 30.495  125.179 1.00 18.84  ? 40  GLU D OE2 1 
ATOM 3866 N N   . ALA D 1 41  ? -34.697 34.621  126.763 1.00 16.22  ? 41  ALA D N   1 
ATOM 3867 C CA  . ALA D 1 41  ? -33.305 34.481  126.337 1.00 16.22  ? 41  ALA D CA  1 
ATOM 3868 C C   . ALA D 1 41  ? -32.356 34.386  127.526 1.00 16.22  ? 41  ALA D C   1 
ATOM 3869 O O   . ALA D 1 41  ? -31.445 33.551  127.539 1.00 16.22  ? 41  ALA D O   1 
ATOM 3870 C CB  . ALA D 1 41  ? -32.910 35.653  125.437 1.00 16.22  ? 41  ALA D CB  1 
ATOM 3871 N N   . LEU D 1 42  ? -32.560 35.231  128.535 1.00 15.07  ? 42  LEU D N   1 
ATOM 3872 C CA  . LEU D 1 42  ? -31.687 35.220  129.708 1.00 15.07  ? 42  LEU D CA  1 
ATOM 3873 C C   . LEU D 1 42  ? -31.709 33.873  130.424 1.00 15.07  ? 42  LEU D C   1 
ATOM 3874 O O   . LEU D 1 42  ? -30.667 33.385  130.876 1.00 15.07  ? 42  LEU D O   1 
ATOM 3875 C CB  . LEU D 1 42  ? -32.101 36.330  130.674 1.00 15.07  ? 42  LEU D CB  1 
ATOM 3876 C CG  . LEU D 1 42  ? -31.728 37.764  130.295 1.00 15.07  ? 42  LEU D CG  1 
ATOM 3877 C CD1 . LEU D 1 42  ? -32.459 38.748  131.193 1.00 15.07  ? 42  LEU D CD1 1 
ATOM 3878 C CD2 . LEU D 1 42  ? -30.227 37.977  130.377 1.00 15.07  ? 42  LEU D CD2 1 
ATOM 3879 N N   . GLU D 1 43  ? -32.883 33.259  130.544 1.00 17.27  ? 43  GLU D N   1 
ATOM 3880 C CA  . GLU D 1 43  ? -33.030 31.944  131.155 1.00 17.27  ? 43  GLU D CA  1 
ATOM 3881 C C   . GLU D 1 43  ? -32.634 30.794  130.238 1.00 17.27  ? 43  GLU D C   1 
ATOM 3882 O O   . GLU D 1 43  ? -32.596 29.648  130.697 1.00 17.27  ? 43  GLU D O   1 
ATOM 3883 C CB  . GLU D 1 43  ? -34.477 31.748  131.608 1.00 17.27  ? 43  GLU D CB  1 
ATOM 3884 C CG  . GLU D 1 43  ? -34.792 32.372  132.952 1.00 17.27  ? 43  GLU D CG  1 
ATOM 3885 C CD  . GLU D 1 43  ? -36.274 32.635  133.143 1.00 17.27  ? 43  GLU D CD  1 
ATOM 3886 O OE1 . GLU D 1 43  ? -37.055 32.356  132.210 1.00 17.27  ? 43  GLU D OE1 1 
ATOM 3887 O OE2 . GLU D 1 43  ? -36.658 33.111  134.231 1.00 17.27  ? 43  GLU D OE2 1 
ATOM 3888 N N   . SER D 1 44  ? -32.345 31.056  128.966 1.00 16.73  ? 44  SER D N   1 
ATOM 3889 C CA  . SER D 1 44  ? -31.976 29.982  128.063 1.00 16.73  ? 44  SER D CA  1 
ATOM 3890 C C   . SER D 1 44  ? -30.583 29.449  128.394 1.00 16.73  ? 44  SER D C   1 
ATOM 3891 O O   . SER D 1 44  ? -29.795 30.111  129.075 1.00 16.73  ? 44  SER D O   1 
ATOM 3892 C CB  . SER D 1 44  ? -32.018 30.472  126.619 1.00 16.73  ? 44  SER D CB  1 
ATOM 3893 O OG  . SER D 1 44  ? -30.876 31.250  126.311 1.00 16.73  ? 44  SER D OG  1 
ATOM 3894 N N   . PRO D 1 45  ? -30.260 28.244  127.920 1.00 17.58  ? 45  PRO D N   1 
ATOM 3895 C CA  . PRO D 1 45  ? -28.899 27.712  128.066 1.00 17.58  ? 45  PRO D CA  1 
ATOM 3896 C C   . PRO D 1 45  ? -27.888 28.227  127.050 1.00 17.58  ? 45  PRO D C   1 
ATOM 3897 O O   . PRO D 1 45  ? -26.750 27.747  127.053 1.00 17.58  ? 45  PRO D O   1 
ATOM 3898 C CB  . PRO D 1 45  ? -29.116 26.202  127.902 1.00 17.58  ? 45  PRO D CB  1 
ATOM 3899 C CG  . PRO D 1 45  ? -30.235 26.111  126.935 1.00 17.58  ? 45  PRO D CG  1 
ATOM 3900 C CD  . PRO D 1 45  ? -31.160 27.252  127.305 1.00 17.58  ? 45  PRO D CD  1 
ATOM 3901 N N   . GLU D 1 46  ? -28.253 29.163  126.182 1.00 18.23  ? 46  GLU D N   1 
ATOM 3902 C CA  . GLU D 1 46  ? -27.337 29.642  125.156 1.00 18.23  ? 46  GLU D CA  1 
ATOM 3903 C C   . GLU D 1 46  ? -26.521 30.830  125.654 1.00 18.23  ? 46  GLU D C   1 
ATOM 3904 O O   . GLU D 1 46  ? -26.987 31.637  126.463 1.00 18.23  ? 46  GLU D O   1 
ATOM 3905 C CB  . GLU D 1 46  ? -28.106 30.043  123.896 1.00 18.23  ? 46  GLU D CB  1 
ATOM 3906 C CG  . GLU D 1 46  ? -28.890 28.908  123.254 1.00 18.23  ? 46  GLU D CG  1 
ATOM 3907 C CD  . GLU D 1 46  ? -28.016 27.720  122.891 1.00 18.23  ? 46  GLU D CD  1 
ATOM 3908 O OE1 . GLU D 1 46  ? -27.105 27.882  122.052 1.00 18.23  ? 46  GLU D OE1 1 
ATOM 3909 O OE2 . GLU D 1 46  ? -28.236 26.626  123.451 1.00 18.23  ? 46  GLU D OE2 1 
ATOM 3910 N N   . HIS D 1 47  ? -25.286 30.923  125.155 1.00 16.91  ? 47  HIS D N   1 
ATOM 3911 C CA  . HIS D 1 47  ? -24.481 32.143  125.241 1.00 16.91  ? 47  HIS D CA  1 
ATOM 3912 C C   . HIS D 1 47  ? -24.971 33.150  124.198 1.00 16.91  ? 47  HIS D C   1 
ATOM 3913 O O   . HIS D 1 47  ? -24.305 33.442  123.203 1.00 16.91  ? 47  HIS D O   1 
ATOM 3914 C CB  . HIS D 1 47  ? -23.004 31.835  125.030 1.00 16.91  ? 47  HIS D CB  1 
ATOM 3915 C CG  . HIS D 1 47  ? -22.404 30.955  126.082 1.00 16.91  ? 47  HIS D CG  1 
ATOM 3916 N ND1 . HIS D 1 47  ? -22.276 31.344  127.397 1.00 16.91  ? 47  HIS D ND1 1 
ATOM 3917 C CD2 . HIS D 1 47  ? -21.859 29.718  126.000 1.00 16.91  ? 47  HIS D CD2 1 
ATOM 3918 C CE1 . HIS D 1 47  ? -21.693 30.378  128.084 1.00 16.91  ? 47  HIS D CE1 1 
ATOM 3919 N NE2 . HIS D 1 47  ? -21.423 29.383  127.259 1.00 16.91  ? 47  HIS D NE2 1 
ATOM 3920 N N   . CYS D 1 48  ? -26.172 33.683  124.435 1.00 16.11  ? 48  CYS D N   1 
ATOM 3921 C CA  . CYS D 1 48  ? -26.799 34.519  123.417 1.00 16.11  ? 48  CYS D CA  1 
ATOM 3922 C C   . CYS D 1 48  ? -25.921 35.719  123.073 1.00 16.11  ? 48  CYS D C   1 
ATOM 3923 O O   . CYS D 1 48  ? -25.765 36.064  121.896 1.00 16.11  ? 48  CYS D O   1 
ATOM 3924 C CB  . CYS D 1 48  ? -28.175 34.982  123.895 1.00 16.11  ? 48  CYS D CB  1 
ATOM 3925 S SG  . CYS D 1 48  ? -29.313 33.637  124.296 1.00 16.11  ? 48  CYS D SG  1 
ATOM 3926 N N   . SER D 1 49  ? -25.334 36.359  124.084 1.00 13.69  ? 49  SER D N   1 
ATOM 3927 C CA  . SER D 1 49  ? -24.304 37.369  123.869 1.00 13.69  ? 49  SER D CA  1 
ATOM 3928 C C   . SER D 1 49  ? -23.617 37.674  125.196 1.00 13.69  ? 49  SER D C   1 
ATOM 3929 O O   . SER D 1 49  ? -24.099 37.261  126.258 1.00 13.69  ? 49  SER D O   1 
ATOM 3930 C CB  . SER D 1 49  ? -24.874 38.647  123.250 1.00 13.69  ? 49  SER D CB  1 
ATOM 3931 O OG  . SER D 1 49  ? -25.598 39.417  124.189 1.00 13.69  ? 49  SER D OG  1 
ATOM 3932 N N   . PRO D 1 50  ? -22.489 38.385  125.174 1.00 13.27  ? 50  PRO D N   1 
ATOM 3933 C CA  . PRO D 1 50  ? -21.872 38.833  126.434 1.00 13.27  ? 50  PRO D CA  1 
ATOM 3934 C C   . PRO D 1 50  ? -22.782 39.692  127.299 1.00 13.27  ? 50  PRO D C   1 
ATOM 3935 O O   . PRO D 1 50  ? -22.667 39.651  128.531 1.00 13.27  ? 50  PRO D O   1 
ATOM 3936 C CB  . PRO D 1 50  ? -20.642 39.620  125.955 1.00 13.27  ? 50  PRO D CB  1 
ATOM 3937 C CG  . PRO D 1 50  ? -20.325 39.034  124.622 1.00 13.27  ? 50  PRO D CG  1 
ATOM 3938 C CD  . PRO D 1 50  ? -21.669 38.758  124.011 1.00 13.27  ? 50  PRO D CD  1 
ATOM 3939 N N   . HIS D 1 51  ? -23.687 40.464  126.694 1.00 12.29  ? 51  HIS D N   1 
ATOM 3940 C CA  . HIS D 1 51  ? -24.673 41.208  127.475 1.00 12.29  ? 51  HIS D CA  1 
ATOM 3941 C C   . HIS D 1 51  ? -25.574 40.293  128.298 1.00 12.29  ? 51  HIS D C   1 
ATOM 3942 O O   . HIS D 1 51  ? -25.871 40.595  129.458 1.00 12.29  ? 51  HIS D O   1 
ATOM 3943 C CB  . HIS D 1 51  ? -25.525 42.076  126.549 1.00 12.29  ? 51  HIS D CB  1 
ATOM 3944 C CG  . HIS D 1 51  ? -24.737 43.032  125.709 1.00 12.29  ? 51  HIS D CG  1 
ATOM 3945 N ND1 . HIS D 1 51  ? -24.281 44.241  126.187 1.00 12.29  ? 51  HIS D ND1 1 
ATOM 3946 C CD2 . HIS D 1 51  ? -24.327 42.958  124.421 1.00 12.29  ? 51  HIS D CD2 1 
ATOM 3947 C CE1 . HIS D 1 51  ? -23.622 44.870  125.231 1.00 12.29  ? 51  HIS D CE1 1 
ATOM 3948 N NE2 . HIS D 1 51  ? -23.639 44.115  124.148 1.00 12.29  ? 51  HIS D NE2 1 
ATOM 3949 N N   . HIS D 1 52  ? -26.020 39.171  127.729 1.00 13.24  ? 52  HIS D N   1 
ATOM 3950 C CA  . HIS D 1 52  ? -26.824 38.234  128.515 1.00 13.24  ? 52  HIS D CA  1 
ATOM 3951 C C   . HIS D 1 52  ? -26.038 37.628  129.671 1.00 13.24  ? 52  HIS D C   1 
ATOM 3952 O O   . HIS D 1 52  ? -26.562 37.511  130.782 1.00 13.24  ? 52  HIS D O   1 
ATOM 3953 C CB  . HIS D 1 52  ? -27.393 37.122  127.631 1.00 13.24  ? 52  HIS D CB  1 
ATOM 3954 C CG  . HIS D 1 52  ? -28.351 37.601  126.586 1.00 13.24  ? 52  HIS D CG  1 
ATOM 3955 N ND1 . HIS D 1 52  ? -27.944 38.089  125.364 1.00 13.24  ? 52  HIS D ND1 1 
ATOM 3956 C CD2 . HIS D 1 52  ? -29.704 37.666  126.584 1.00 13.24  ? 52  HIS D CD2 1 
ATOM 3957 C CE1 . HIS D 1 52  ? -29.003 38.433  124.653 1.00 13.24  ? 52  HIS D CE1 1 
ATOM 3958 N NE2 . HIS D 1 52  ? -30.083 38.186  125.370 1.00 13.24  ? 52  HIS D NE2 1 
ATOM 3959 N N   . THR D 1 53  ? -24.784 37.255  129.433 1.00 13.05  ? 53  THR D N   1 
ATOM 3960 C CA  . THR D 1 53  ? -23.916 36.660  130.477 1.00 13.05  ? 53  THR D CA  1 
ATOM 3961 C C   . THR D 1 53  ? -23.791 37.660  131.615 1.00 13.05  ? 53  THR D C   1 
ATOM 3962 O O   . THR D 1 53  ? -24.122 37.309  132.786 1.00 13.05  ? 53  THR D O   1 
ATOM 3963 C CB  . THR D 1 53  ? -22.548 36.301  129.903 1.00 13.05  ? 53  THR D CB  1 
ATOM 3964 O OG1 . THR D 1 53  ? -22.749 35.352  128.857 1.00 13.05  ? 53  THR D OG1 1 
ATOM 3965 C CG2 . THR D 1 53  ? -21.603 35.733  130.938 1.00 13.05  ? 53  THR D CG2 1 
ATOM 3966 N N   . ALA D 1 54  ? -23.361 38.872  131.301 1.00 12.71  ? 54  ALA D N   1 
ATOM 3967 C CA  . ALA D 1 54  ? -23.191 39.942  132.299 1.00 12.71  ? 54  ALA D CA  1 
ATOM 3968 C C   . ALA D 1 54  ? -24.497 40.150  133.052 1.00 12.71  ? 54  ALA D C   1 
ATOM 3969 O O   . ALA D 1 54  ? -24.473 40.119  134.298 1.00 12.71  ? 54  ALA D O   1 
ATOM 3970 C CB  . ALA D 1 54  ? -22.780 41.191  131.591 1.00 12.71  ? 54  ALA D CB  1 
ATOM 3971 N N   . LEU D 1 55  ? -25.601 40.330  132.334 1.00 12.93  ? 55  LEU D N   1 
ATOM 3972 C CA  . LEU D 1 55  ? -26.906 40.611  132.970 1.00 12.93  ? 55  LEU D CA  1 
ATOM 3973 C C   . LEU D 1 55  ? -27.244 39.456  133.904 1.00 12.93  ? 55  LEU D C   1 
ATOM 3974 O O   . LEU D 1 55  ? -27.613 39.734  135.035 1.00 12.93  ? 55  LEU D O   1 
ATOM 3975 C CB  . LEU D 1 55  ? -27.974 40.800  131.896 1.00 12.93  ? 55  LEU D CB  1 
ATOM 3976 C CG  . LEU D 1 55  ? -28.027 42.191  131.271 1.00 12.93  ? 55  LEU D CG  1 
ATOM 3977 C CD1 . LEU D 1 55  ? -28.938 42.202  130.057 1.00 12.93  ? 55  LEU D CD1 1 
ATOM 3978 C CD2 . LEU D 1 55  ? -28.480 43.224  132.287 1.00 12.93  ? 55  LEU D CD2 1 
ATOM 3979 N N   . ARG D 1 56  ? -27.086 38.214  133.462 1.00 13.99  ? 56  ARG D N   1 
ATOM 3980 C CA  . ARG D 1 56  ? -27.373 37.025  134.297 1.00 13.99  ? 56  ARG D CA  1 
ATOM 3981 C C   . ARG D 1 56  ? -26.588 37.143  135.603 1.00 13.99  ? 56  ARG D C   1 
ATOM 3982 O O   . ARG D 1 56  ? -27.221 37.149  136.700 1.00 13.99  ? 56  ARG D O   1 
ATOM 3983 C CB  . ARG D 1 56  ? -27.001 35.748  133.544 1.00 13.99  ? 56  ARG D CB  1 
ATOM 3984 C CG  . ARG D 1 56  ? -27.955 35.379  132.421 1.00 13.99  ? 56  ARG D CG  1 
ATOM 3985 C CD  . ARG D 1 56  ? -27.263 34.524  131.382 1.00 13.99  ? 56  ARG D CD  1 
ATOM 3986 N NE  . ARG D 1 56  ? -28.145 34.194  130.278 1.00 13.99  ? 56  ARG D NE  1 
ATOM 3987 C CZ  . ARG D 1 56  ? -27.750 33.659  129.130 1.00 13.99  ? 56  ARG D CZ  1 
ATOM 3988 N NH1 . ARG D 1 56  ? -26.472 33.397  128.920 1.00 13.99  ? 56  ARG D NH1 1 
ATOM 3989 N NH2 . ARG D 1 56  ? -28.635 33.398  128.188 1.00 13.99  ? 56  ARG D NH2 1 
ATOM 3990 N N   . GLN D 1 57  ? -25.261 37.210  135.539 1.00 13.60  ? 57  GLN D N   1 
ATOM 3991 C CA  . GLN D 1 57  ? -24.426 37.205  136.762 1.00 13.60  ? 57  GLN D CA  1 
ATOM 3992 C C   . GLN D 1 57  ? -24.920 38.302  137.692 1.00 13.60  ? 57  GLN D C   1 
ATOM 3993 O O   . GLN D 1 57  ? -25.128 38.012  138.891 1.00 13.60  ? 57  GLN D O   1 
ATOM 3994 C CB  . GLN D 1 57  ? -22.966 37.397  136.388 1.00 13.60  ? 57  GLN D CB  1 
ATOM 3995 C CG  . GLN D 1 57  ? -22.392 36.275  135.537 1.00 13.60  ? 57  GLN D CG  1 
ATOM 3996 C CD  . GLN D 1 57  ? -22.440 34.924  136.207 1.00 13.60  ? 57  GLN D CD  1 
ATOM 3997 O OE1 . GLN D 1 57  ? -22.675 34.818  137.408 1.00 13.60  ? 57  GLN D OE1 1 
ATOM 3998 N NE2 . GLN D 1 57  ? -22.208 33.873  135.441 1.00 13.60  ? 57  GLN D NE2 1 
ATOM 3999 N N   . ALA D 1 58  ? -25.180 39.492  137.166 1.00 13.40  ? 58  ALA D N   1 
ATOM 4000 C CA  . ALA D 1 58  ? -25.598 40.660  137.975 1.00 13.40  ? 58  ALA D CA  1 
ATOM 4001 C C   . ALA D 1 58  ? -26.916 40.397  138.688 1.00 13.40  ? 58  ALA D C   1 
ATOM 4002 O O   . ALA D 1 58  ? -27.023 40.763  139.854 1.00 13.40  ? 58  ALA D O   1 
ATOM 4003 C CB  . ALA D 1 58  ? -25.733 41.853  137.087 1.00 13.40  ? 58  ALA D CB  1 
ATOM 4004 N N   . ILE D 1 59  ? -27.885 39.813  137.999 1.00 14.00  ? 59  ILE D N   1 
ATOM 4005 C CA  . ILE D 1 59  ? -29.217 39.525  138.590 1.00 14.00  ? 59  ILE D CA  1 
ATOM 4006 C C   . ILE D 1 59  ? -29.003 38.541  139.738 1.00 14.00  ? 59  ILE D C   1 
ATOM 4007 O O   . ILE D 1 59  ? -29.536 38.801  140.819 1.00 14.00  ? 59  ILE D O   1 
ATOM 4008 C CB  . ILE D 1 59  ? -30.186 39.000  137.519 1.00 14.00  ? 59  ILE D CB  1 
ATOM 4009 C CG1 . ILE D 1 59  ? -30.420 40.030  136.413 1.00 14.00  ? 59  ILE D CG1 1 
ATOM 4010 C CG2 . ILE D 1 59  ? -31.491 38.556  138.152 1.00 14.00  ? 59  ILE D CG2 1 
ATOM 4011 C CD1 . ILE D 1 59  ? -30.824 39.425  135.092 1.00 14.00  ? 59  ILE D CD1 1 
ATOM 4012 N N   . LEU D 1 60  ? -28.205 37.494  139.539 1.00 15.10  ? 60  LEU D N   1 
ATOM 4013 C CA  . LEU D 1 60  ? -27.938 36.495  140.596 1.00 15.10  ? 60  LEU D CA  1 
ATOM 4014 C C   . LEU D 1 60  ? -27.336 37.228  141.784 1.00 15.10  ? 60  LEU D C   1 
ATOM 4015 O O   . LEU D 1 60  ? -27.762 36.970  142.914 1.00 15.10  ? 60  LEU D O   1 
ATOM 4016 C CB  . LEU D 1 60  ? -26.972 35.441  140.068 1.00 15.10  ? 60  LEU D CB  1 
ATOM 4017 C CG  . LEU D 1 60  ? -27.445 34.645  138.857 1.00 15.10  ? 60  LEU D CG  1 
ATOM 4018 C CD1 . LEU D 1 60  ? -26.306 33.829  138.270 1.00 15.10  ? 60  LEU D CD1 1 
ATOM 4019 C CD2 . LEU D 1 60  ? -28.610 33.745  139.221 1.00 15.10  ? 60  LEU D CD2 1 
ATOM 4020 N N   . CYS D 1 61  ? -26.401 38.129  141.536 1.00 16.15  ? 61  CYS D N   1 
ATOM 4021 C CA  . CYS D 1 61  ? -25.700 38.886  142.601 1.00 16.15  ? 61  CYS D CA  1 
ATOM 4022 C C   . CYS D 1 61  ? -26.699 39.742  143.385 1.00 16.15  ? 61  CYS D C   1 
ATOM 4023 O O   . CYS D 1 61  ? -26.659 39.722  144.638 1.00 16.15  ? 61  CYS D O   1 
ATOM 4024 C CB  . CYS D 1 61  ? -24.636 39.744  141.936 1.00 16.15  ? 61  CYS D CB  1 
ATOM 4025 S SG  . CYS D 1 61  ? -23.508 40.599  143.061 1.00 16.15  ? 61  CYS D SG  1 
ATOM 4026 N N   . TRP D 1 62  ? -27.577 40.467  142.695 1.00 16.37  ? 62  TRP D N   1 
ATOM 4027 C CA  . TRP D 1 62  ? -28.572 41.351  143.347 1.00 16.37  ? 62  TRP D CA  1 
ATOM 4028 C C   . TRP D 1 62  ? -29.496 40.481  144.174 1.00 16.37  ? 62  TRP D C   1 
ATOM 4029 O O   . TRP D 1 62  ? -29.931 40.934  145.216 1.00 16.37  ? 62  TRP D O   1 
ATOM 4030 C CB  . TRP D 1 62  ? -29.354 42.172  142.324 1.00 16.37  ? 62  TRP D CB  1 
ATOM 4031 C CG  . TRP D 1 62  ? -30.335 43.125  142.935 1.00 16.37  ? 62  TRP D CG  1 
ATOM 4032 C CD1 . TRP D 1 62  ? -31.695 43.074  142.847 1.00 16.37  ? 62  TRP D CD1 1 
ATOM 4033 C CD2 . TRP D 1 62  ? -30.033 44.276  143.743 1.00 16.37  ? 62  TRP D CD2 1 
ATOM 4034 N NE1 . TRP D 1 62  ? -32.258 44.113  143.535 1.00 16.37  ? 62  TRP D NE1 1 
ATOM 4035 C CE2 . TRP D 1 62  ? -31.262 44.866  144.097 1.00 16.37  ? 62  TRP D CE2 1 
ATOM 4036 C CE3 . TRP D 1 62  ? -28.849 44.864  144.199 1.00 16.37  ? 62  TRP D CE3 1 
ATOM 4037 C CZ2 . TRP D 1 62  ? -31.337 46.013  144.884 1.00 16.37  ? 62  TRP D CZ2 1 
ATOM 4038 C CZ3 . TRP D 1 62  ? -28.924 45.998  144.977 1.00 16.37  ? 62  TRP D CZ3 1 
ATOM 4039 C CH2 . TRP D 1 62  ? -30.153 46.562  145.313 1.00 16.37  ? 62  TRP D CH2 1 
ATOM 4040 N N   . GLY D 1 63  ? -29.790 39.287  143.691 1.00 18.17  ? 63  GLY D N   1 
ATOM 4041 C CA  . GLY D 1 63  ? -30.634 38.344  144.434 1.00 18.17  ? 63  GLY D CA  1 
ATOM 4042 C C   . GLY D 1 63  ? -29.948 37.937  145.712 1.00 18.17  ? 63  GLY D C   1 
ATOM 4043 O O   . GLY D 1 63  ? -30.576 38.034  146.752 1.00 18.17  ? 63  GLY D O   1 
ATOM 4044 N N   . GLU D 1 64  ? -28.696 37.512  145.640 1.00 19.57  ? 64  GLU D N   1 
ATOM 4045 C CA  . GLU D 1 64  ? -27.922 37.139  146.842 1.00 19.57  ? 64  GLU D CA  1 
ATOM 4046 C C   . GLU D 1 64  ? -27.940 38.318  147.806 1.00 19.57  ? 64  GLU D C   1 
ATOM 4047 O O   . GLU D 1 64  ? -27.923 38.080  149.017 1.00 19.57  ? 64  GLU D O   1 
ATOM 4048 C CB  . GLU D 1 64  ? -26.487 36.775  146.481 1.00 19.57  ? 64  GLU D CB  1 
ATOM 4049 C CG  . GLU D 1 64  ? -26.378 35.620  145.514 1.00 19.57  ? 64  GLU D CG  1 
ATOM 4050 C CD  . GLU D 1 64  ? -27.458 34.578  145.713 1.00 19.57  ? 64  GLU D CD  1 
ATOM 4051 O OE1 . GLU D 1 64  ? -28.359 34.498  144.860 1.00 19.57  ? 64  GLU D OE1 1 
ATOM 4052 O OE2 . GLU D 1 64  ? -27.400 33.863  146.728 1.00 19.57  ? 64  GLU D OE2 1 
ATOM 4053 N N   . LEU D 1 65  ? -27.962 39.537  147.285 1.00 20.86  ? 65  LEU D N   1 
ATOM 4054 C CA  . LEU D 1 65  ? -27.938 40.745  148.145 1.00 20.86  ? 65  LEU D CA  1 
ATOM 4055 C C   . LEU D 1 65  ? -29.275 40.898  148.857 1.00 20.86  ? 65  LEU D C   1 
ATOM 4056 O O   . LEU D 1 65  ? -29.263 41.053  150.063 1.00 20.86  ? 65  LEU D O   1 
ATOM 4057 C CB  . LEU D 1 65  ? -27.666 41.978  147.289 1.00 20.86  ? 65  LEU D CB  1 
ATOM 4058 C CG  . LEU D 1 65  ? -26.300 42.033  146.617 1.00 20.86  ? 65  LEU D CG  1 
ATOM 4059 C CD1 . LEU D 1 65  ? -26.218 43.227  145.685 1.00 20.86  ? 65  LEU D CD1 1 
ATOM 4060 C CD2 . LEU D 1 65  ? -25.188 42.088  147.649 1.00 20.86  ? 65  LEU D CD2 1 
ATOM 4061 N N   . MET D 1 66  ? -30.375 40.891  148.123 1.00 22.14  ? 66  MET D N   1 
ATOM 4062 C CA  . MET D 1 66  ? -31.743 41.015  148.684 1.00 22.14  ? 66  MET D CA  1 
ATOM 4063 C C   . MET D 1 66  ? -31.938 39.919  149.728 1.00 22.14  ? 66  MET D C   1 
ATOM 4064 O O   . MET D 1 66  ? -32.592 40.184  150.777 1.00 22.14  ? 66  MET D O   1 
ATOM 4065 C CB  . MET D 1 66  ? -32.794 40.887  147.584 1.00 22.14  ? 66  MET D CB  1 
ATOM 4066 C CG  . MET D 1 66  ? -32.760 42.017  146.578 1.00 22.14  ? 66  MET D CG  1 
ATOM 4067 S SD  . MET D 1 66  ? -32.766 43.652  147.347 1.00 22.14  ? 66  MET D SD  1 
ATOM 4068 C CE  . MET D 1 66  ? -31.006 43.962  147.469 1.00 22.14  ? 66  MET D CE  1 
ATOM 4069 N N   . THR D 1 67  ? -31.406 38.729  149.472 1.00 24.27  ? 67  THR D N   1 
ATOM 4070 C CA  . THR D 1 67  ? -31.467 37.623  150.452 1.00 24.27  ? 67  THR D CA  1 
ATOM 4071 C C   . THR D 1 67  ? -30.759 38.095  151.714 1.00 24.27  ? 67  THR D C   1 
ATOM 4072 O O   . THR D 1 67  ? -31.327 37.912  152.791 1.00 24.27  ? 67  THR D O   1 
ATOM 4073 C CB  . THR D 1 67  ? -30.823 36.348  149.908 1.00 24.27  ? 67  THR D CB  1 
ATOM 4074 O OG1 . THR D 1 67  ? -31.663 35.840  148.875 1.00 24.27  ? 67  THR D OG1 1 
ATOM 4075 C CG2 . THR D 1 67  ? -30.621 35.295  150.975 1.00 24.27  ? 67  THR D CG2 1 
ATOM 4076 N N   . LEU D 1 68  ? -29.585 38.705  151.574 1.00 25.71  ? 68  LEU D N   1 
ATOM 4077 C CA  . LEU D 1 68  ? -28.810 39.211  152.734 1.00 25.71  ? 68  LEU D CA  1 
ATOM 4078 C C   . LEU D 1 68  ? -29.651 40.226  153.484 1.00 25.71  ? 68  LEU D C   1 
ATOM 4079 O O   . LEU D 1 68  ? -29.637 40.189  154.711 1.00 25.71  ? 68  LEU D O   1 
ATOM 4080 C CB  . LEU D 1 68  ? -27.520 39.874  152.260 1.00 25.71  ? 68  LEU D CB  1 
ATOM 4081 C CG  . LEU D 1 68  ? -26.804 40.729  153.300 1.00 25.71  ? 68  LEU D CG  1 
ATOM 4082 C CD1 . LEU D 1 68  ? -26.448 39.910  154.527 1.00 25.71  ? 68  LEU D CD1 1 
ATOM 4083 C CD2 . LEU D 1 68  ? -25.559 41.359  152.703 1.00 25.71  ? 68  LEU D CD2 1 
ATOM 4084 N N   . ALA D 1 69  ? -30.323 41.121  152.774 1.00 28.06  ? 69  ALA D N   1 
ATOM 4085 C CA  . ALA D 1 69  ? -31.184 42.149  153.391 1.00 28.06  ? 69  ALA D CA  1 
ATOM 4086 C C   . ALA D 1 69  ? -32.254 41.469  154.241 1.00 28.06  ? 69  ALA D C   1 
ATOM 4087 O O   . ALA D 1 69  ? -32.388 41.834  155.420 1.00 28.06  ? 69  ALA D O   1 
ATOM 4088 C CB  . ALA D 1 69  ? -31.801 42.996  152.323 1.00 28.06  ? 69  ALA D CB  1 
ATOM 4089 N N   . THR D 1 70  ? -32.963 40.487  153.689 1.00 30.27  ? 70  THR D N   1 
ATOM 4090 C CA  . THR D 1 70  ? -34.021 39.757  154.431 1.00 30.27  ? 70  THR D CA  1 
ATOM 4091 C C   . THR D 1 70  ? -33.406 39.077  155.654 1.00 30.27  ? 70  THR D C   1 
ATOM 4092 O O   . THR D 1 70  ? -34.057 39.067  156.727 1.00 30.27  ? 70  THR D O   1 
ATOM 4093 C CB  . THR D 1 70  ? -34.704 38.718  153.544 1.00 30.27  ? 70  THR D CB  1 
ATOM 4094 O OG1 . THR D 1 70  ? -35.367 39.414  152.489 1.00 30.27  ? 70  THR D OG1 1 
ATOM 4095 C CG2 . THR D 1 70  ? -35.694 37.861  154.299 1.00 30.27  ? 70  THR D CG2 1 
ATOM 4096 N N   . TRP D 1 71  ? -32.214 38.507  155.503 1.00 31.35  ? 71  TRP D N   1 
ATOM 4097 C CA  . TRP D 1 71  ? -31.518 37.801  156.603 1.00 31.35  ? 71  TRP D CA  1 
ATOM 4098 C C   . TRP D 1 71  ? -31.233 38.788  157.719 1.00 31.35  ? 71  TRP D C   1 
ATOM 4099 O O   . TRP D 1 71  ? -31.468 38.423  158.852 1.00 31.35  ? 71  TRP D O   1 
ATOM 4100 C CB  . TRP D 1 71  ? -30.228 37.148  156.109 1.00 31.35  ? 71  TRP D CB  1 
ATOM 4101 C CG  . TRP D 1 71  ? -29.388 36.548  157.191 1.00 31.35  ? 71  TRP D CG  1 
ATOM 4102 C CD1 . TRP D 1 71  ? -29.343 35.238  157.566 1.00 31.35  ? 71  TRP D CD1 1 
ATOM 4103 C CD2 . TRP D 1 71  ? -28.454 37.239  158.038 1.00 31.35  ? 71  TRP D CD2 1 
ATOM 4104 N NE1 . TRP D 1 71  ? -28.446 35.067  158.584 1.00 31.35  ? 71  TRP D NE1 1 
ATOM 4105 C CE2 . TRP D 1 71  ? -27.888 36.277  158.897 1.00 31.35  ? 71  TRP D CE2 1 
ATOM 4106 C CE3 . TRP D 1 71  ? -28.044 38.570  158.153 1.00 31.35  ? 71  TRP D CE3 1 
ATOM 4107 C CZ2 . TRP D 1 71  ? -26.936 36.608  159.857 1.00 31.35  ? 71  TRP D CZ2 1 
ATOM 4108 C CZ3 . TRP D 1 71  ? -27.102 38.896  159.103 1.00 31.35  ? 71  TRP D CZ3 1 
ATOM 4109 C CH2 . TRP D 1 71  ? -26.557 37.927  159.942 1.00 31.35  ? 71  TRP D CH2 1 
ATOM 4110 N N   . VAL D 1 72  ? -30.728 39.977  157.403 1.00 33.70  ? 72  VAL D N   1 
ATOM 4111 C CA  . VAL D 1 72  ? -30.446 41.029  158.417 1.00 33.70  ? 72  VAL D CA  1 
ATOM 4112 C C   . VAL D 1 72  ? -31.767 41.357  159.088 1.00 33.70  ? 72  VAL D C   1 
ATOM 4113 O O   . VAL D 1 72  ? -31.799 41.480  160.313 1.00 33.70  ? 72  VAL D O   1 
ATOM 4114 C CB  . VAL D 1 72  ? -29.824 42.285  157.789 1.00 33.70  ? 72  VAL D CB  1 
ATOM 4115 C CG1 . VAL D 1 72  ? -29.650 43.402  158.807 1.00 33.70  ? 72  VAL D CG1 1 
ATOM 4116 C CG2 . VAL D 1 72  ? -28.505 41.972  157.102 1.00 33.70  ? 72  VAL D CG2 1 
ATOM 4117 N N   . GLY D 1 73  ? -32.817 41.518  158.298 1.00 36.09  ? 73  GLY D N   1 
ATOM 4118 C CA  . GLY D 1 73  ? -34.156 41.791  158.838 1.00 36.09  ? 73  GLY D CA  1 
ATOM 4119 C C   . GLY D 1 73  ? -34.557 40.784  159.893 1.00 36.09  ? 73  GLY D C   1 
ATOM 4120 O O   . GLY D 1 73  ? -35.024 41.220  160.960 1.00 36.09  ? 73  GLY D O   1 
ATOM 4121 N N   . VAL D 1 74  ? -34.356 39.491  159.639 1.00 37.53  ? 74  VAL D N   1 
ATOM 4122 C CA  . VAL D 1 74  ? -34.843 38.423  160.566 1.00 37.53  ? 74  VAL D CA  1 
ATOM 4123 C C   . VAL D 1 74  ? -33.831 38.095  161.666 1.00 37.53  ? 74  VAL D C   1 
ATOM 4124 O O   . VAL D 1 74  ? -34.259 37.474  162.659 1.00 37.53  ? 74  VAL D O   1 
ATOM 4125 C CB  . VAL D 1 74  ? -35.174 37.158  159.756 1.00 30.00  ? 74  VAL D CB  1 
ATOM 4126 C CG1 . VAL D 1 74  ? -35.439 35.954  160.642 1.00 30.00  ? 74  VAL D CG1 1 
ATOM 4127 C CG2 . VAL D 1 74  ? -36.338 37.396  158.809 1.00 30.00  ? 74  VAL D CG2 1 
ATOM 4128 N N   . ASN D 1 75  ? -32.543 38.385  161.475 1.00 36.10  ? 75  ASN D N   1 
ATOM 4129 C CA  . ASN D 1 75  ? -31.491 37.938  162.429 1.00 36.10  ? 75  ASN D CA  1 
ATOM 4130 C C   . ASN D 1 75  ? -30.604 39.091  162.882 1.00 36.10  ? 75  ASN D C   1 
ATOM 4131 O O   . ASN D 1 75  ? -29.420 39.100  162.521 1.00 36.10  ? 75  ASN D O   1 
ATOM 4132 C CB  . ASN D 1 75  ? -30.624 36.852  161.800 1.00 36.10  ? 75  ASN D CB  1 
ATOM 4133 C CG  . ASN D 1 75  ? -31.440 35.862  161.004 1.00 36.10  ? 75  ASN D CG  1 
ATOM 4134 O OD1 . ASN D 1 75  ? -32.256 35.134  161.563 1.00 36.10  ? 75  ASN D OD1 1 
ATOM 4135 N ND2 . ASN D 1 75  ? -31.241 35.845  159.698 1.00 36.10  ? 75  ASN D ND2 1 
ATOM 4136 N N   . LEU D 1 76  ? -31.137 40.010  163.671 1.00 38.58  ? 76  LEU D N   1 
ATOM 4137 C CA  . LEU D 1 76  ? -30.328 41.111  164.235 1.00 38.58  ? 76  LEU D CA  1 
ATOM 4138 C C   . LEU D 1 76  ? -30.907 41.477  165.599 1.00 38.58  ? 76  LEU D C   1 
ATOM 4139 O O   . LEU D 1 76  ? -32.080 41.149  165.840 1.00 38.58  ? 76  LEU D O   1 
ATOM 4140 C CB  . LEU D 1 76  ? -30.348 42.300  163.276 1.00 38.58  ? 76  LEU D CB  1 
ATOM 4141 C CG  . LEU D 1 76  ? -29.097 42.514  162.426 1.00 38.58  ? 76  LEU D CG  1 
ATOM 4142 C CD1 . LEU D 1 76  ? -29.027 43.955  161.952 1.00 38.58  ? 76  LEU D CD1 1 
ATOM 4143 C CD2 . LEU D 1 76  ? -27.829 42.149  163.183 1.00 38.58  ? 76  LEU D CD2 1 
ATOM 4144 N N   . GLU D 1 77  ? -30.120 42.129  166.448 1.00 43.71  ? 77  GLU D N   1 
ATOM 4145 C CA  . GLU D 1 77  ? -30.539 42.483  167.825 1.00 43.71  ? 77  GLU D CA  1 
ATOM 4146 C C   . GLU D 1 77  ? -30.581 44.004  167.911 1.00 43.71  ? 77  GLU D C   1 
ATOM 4147 O O   . GLU D 1 77  ? -30.574 44.527  169.031 1.00 43.71  ? 77  GLU D O   1 
ATOM 4148 C CB  . GLU D 1 77  ? -29.566 41.874  168.833 1.00 43.71  ? 77  GLU D CB  1 
ATOM 4149 C CG  . GLU D 1 77  ? -29.596 40.355  168.895 1.00 43.71  ? 77  GLU D CG  1 
ATOM 4150 C CD  . GLU D 1 77  ? -28.584 39.727  169.841 1.00 43.71  ? 77  GLU D CD  1 
ATOM 4151 O OE1 . GLU D 1 77  ? -27.704 40.460  170.334 1.00 43.71  ? 77  GLU D OE1 1 
ATOM 4152 O OE2 . GLU D 1 77  ? -28.677 38.507  170.077 1.00 43.71  ? 77  GLU D OE2 1 
ATOM 4153 N N   . ASP D 1 78  ? -30.639 44.677  166.771 1.00 43.94  ? 78  ASP D N   1 
ATOM 4154 C CA  . ASP D 1 78  ? -30.644 46.162  166.705 1.00 43.94  ? 78  ASP D CA  1 
ATOM 4155 C C   . ASP D 1 78  ? -31.462 46.649  165.501 1.00 43.94  ? 78  ASP D C   1 
ATOM 4156 O O   . ASP D 1 78  ? -31.149 46.234  164.370 1.00 43.94  ? 78  ASP D O   1 
ATOM 4157 C CB  . ASP D 1 78  ? -29.199 46.668  166.692 1.00 43.94  ? 78  ASP D CB  1 
ATOM 4158 C CG  . ASP D 1 78  ? -29.045 48.178  166.699 1.00 43.94  ? 78  ASP D CG  1 
ATOM 4159 O OD1 . ASP D 1 78  ? -30.024 48.868  167.037 1.00 43.94  ? 78  ASP D OD1 1 
ATOM 4160 O OD2 . ASP D 1 78  ? -27.936 48.652  166.382 1.00 43.94  ? 78  ASP D OD2 1 
ATOM 4161 N N   . PRO D 1 79  ? -32.513 47.477  165.701 1.00 43.15  ? 79  PRO D N   1 
ATOM 4162 C CA  . PRO D 1 79  ? -33.275 48.083  164.605 1.00 43.15  ? 79  PRO D CA  1 
ATOM 4163 C C   . PRO D 1 79  ? -32.463 49.131  163.831 1.00 43.15  ? 79  PRO D C   1 
ATOM 4164 O O   . PRO D 1 79  ? -32.685 49.248  162.647 1.00 43.15  ? 79  PRO D O   1 
ATOM 4165 C CB  . PRO D 1 79  ? -34.455 48.752  165.323 1.00 43.15  ? 79  PRO D CB  1 
ATOM 4166 C CG  . PRO D 1 79  ? -33.897 49.086  166.685 1.00 43.15  ? 79  PRO D CG  1 
ATOM 4167 C CD  . PRO D 1 79  ? -33.001 47.911  167.014 1.00 43.15  ? 79  PRO D CD  1 
ATOM 4168 N N   . ALA D 1 80  ? -31.637 49.902  164.539 1.00 41.16  ? 80  ALA D N   1 
ATOM 4169 C CA  . ALA D 1 80  ? -30.830 50.981  163.937 1.00 41.16  ? 80  ALA D CA  1 
ATOM 4170 C C   . ALA D 1 80  ? -29.841 50.365  162.961 1.00 41.16  ? 80  ALA D C   1 
ATOM 4171 O O   . ALA D 1 80  ? -29.839 50.771  161.789 1.00 41.16  ? 80  ALA D O   1 
ATOM 4172 C CB  . ALA D 1 80  ? -30.119 51.744  165.016 1.00 41.16  ? 80  ALA D CB  1 
ATOM 4173 N N   . SER D 1 81  ? -29.033 49.422  163.428 1.00 40.38  ? 81  SER D N   1 
ATOM 4174 C CA  . SER D 1 81  ? -28.051 48.729  162.567 1.00 40.38  ? 81  SER D CA  1 
ATOM 4175 C C   . SER D 1 81  ? -28.815 48.099  161.409 1.00 40.38  ? 81  SER D C   1 
ATOM 4176 O O   . SER D 1 81  ? -28.375 48.258  160.262 1.00 40.38  ? 81  SER D O   1 
ATOM 4177 C CB  . SER D 1 81  ? -27.273 47.712  163.341 1.00 40.38  ? 81  SER D CB  1 
ATOM 4178 O OG  . SER D 1 81  ? -28.112 46.651  163.767 1.00 40.38  ? 81  SER D OG  1 
ATOM 4179 N N   . ARG D 1 82  ? -29.944 47.458  161.691 1.00 39.67  ? 82  ARG D N   1 
ATOM 4180 C CA  . ARG D 1 82  ? -30.747 46.783  160.647 1.00 39.67  ? 82  ARG D CA  1 
ATOM 4181 C C   . ARG D 1 82  ? -31.065 47.814  159.572 1.00 39.67  ? 82  ARG D C   1 
ATOM 4182 O O   . ARG D 1 82  ? -30.813 47.529  158.392 1.00 39.67  ? 82  ARG D O   1 
ATOM 4183 C CB  . ARG D 1 82  ? -31.990 46.161  161.284 1.00 39.67  ? 82  ARG D CB  1 
ATOM 4184 C CG  . ARG D 1 82  ? -33.022 45.660  160.287 1.00 39.67  ? 82  ARG D CG  1 
ATOM 4185 C CD  . ARG D 1 82  ? -34.041 44.745  160.937 1.00 39.67  ? 82  ARG D CD  1 
ATOM 4186 N NE  . ARG D 1 82  ? -34.476 45.210  162.249 1.00 39.67  ? 82  ARG D NE  1 
ATOM 4187 C CZ  . ARG D 1 82  ? -33.953 44.824  163.410 1.00 39.67  ? 82  ARG D CZ  1 
ATOM 4188 N NH1 . ARG D 1 82  ? -32.956 43.958  163.445 1.00 39.67  ? 82  ARG D NH1 1 
ATOM 4189 N NH2 . ARG D 1 82  ? -34.433 45.306  164.542 1.00 39.67  ? 82  ARG D NH2 1 
ATOM 4190 N N   . ASP D 1 83  ? -31.530 48.991  159.965 1.00 38.67  ? 83  ASP D N   1 
ATOM 4191 C CA  . ASP D 1 83  ? -31.910 50.049  159.001 1.00 38.67  ? 83  ASP D CA  1 
ATOM 4192 C C   . ASP D 1 83  ? -30.657 50.525  158.273 1.00 38.67  ? 83  ASP D C   1 
ATOM 4193 O O   . ASP D 1 83  ? -30.697 50.609  157.038 1.00 38.67  ? 83  ASP D O   1 
ATOM 4194 C CB  . ASP D 1 83  ? -32.621 51.189  159.721 1.00 38.67  ? 83  ASP D CB  1 
ATOM 4195 C CG  . ASP D 1 83  ? -33.862 50.741  160.472 1.00 38.67  ? 83  ASP D CG  1 
ATOM 4196 O OD1 . ASP D 1 83  ? -34.259 49.573  160.299 1.00 38.67  ? 83  ASP D OD1 1 
ATOM 4197 O OD2 . ASP D 1 83  ? -34.413 51.560  161.230 1.00 38.67  ? 83  ASP D OD2 1 
ATOM 4198 N N   . LEU D 1 84  ? -29.579 50.795  159.002 1.00 36.56  ? 84  LEU D N   1 
ATOM 4199 C CA  . LEU D 1 84  ? -28.331 51.328  158.403 1.00 36.56  ? 84  LEU D CA  1 
ATOM 4200 C C   . LEU D 1 84  ? -27.871 50.393  157.291 1.00 36.56  ? 84  LEU D C   1 
ATOM 4201 O O   . LEU D 1 84  ? -27.550 50.891  156.204 1.00 36.56  ? 84  LEU D O   1 
ATOM 4202 C CB  . LEU D 1 84  ? -27.270 51.435  159.495 1.00 36.56  ? 84  LEU D CB  1 
ATOM 4203 C CG  . LEU D 1 84  ? -27.469 52.573  160.491 1.00 36.56  ? 84  LEU D CG  1 
ATOM 4204 C CD1 . LEU D 1 84  ? -26.740 52.287  161.792 1.00 36.56  ? 84  LEU D CD1 1 
ATOM 4205 C CD2 . LEU D 1 84  ? -27.008 53.891  159.894 1.00 36.56  ? 84  LEU D CD2 1 
ATOM 4206 N N   . VAL D 1 85  ? -27.852 49.089  157.539 1.00 33.30  ? 85  VAL D N   1 
ATOM 4207 C CA  . VAL D 1 85  ? -27.349 48.101  156.547 1.00 33.30  ? 85  VAL D CA  1 
ATOM 4208 C C   . VAL D 1 85  ? -28.299 48.076  155.358 1.00 33.30  ? 85  VAL D C   1 
ATOM 4209 O O   . VAL D 1 85  ? -27.821 48.251  154.227 1.00 33.30  ? 85  VAL D O   1 
ATOM 4210 C CB  . VAL D 1 85  ? -27.215 46.707  157.177 1.00 33.30  ? 85  VAL D CB  1 
ATOM 4211 C CG1 . VAL D 1 85  ? -27.048 45.627  156.123 1.00 33.30  ? 85  VAL D CG1 1 
ATOM 4212 C CG2 . VAL D 1 85  ? -26.084 46.653  158.187 1.00 33.30  ? 85  VAL D CG2 1 
ATOM 4213 N N   . VAL D 1 86  ? -29.594 47.908  155.597 1.00 31.99  ? 86  VAL D N   1 
ATOM 4214 C CA  . VAL D 1 86  ? -30.587 47.774  154.497 1.00 31.99  ? 86  VAL D CA  1 
ATOM 4215 C C   . VAL D 1 86  ? -30.494 49.005  153.602 1.00 31.99  ? 86  VAL D C   1 
ATOM 4216 O O   . VAL D 1 86  ? -30.579 48.844  152.376 1.00 31.99  ? 86  VAL D O   1 
ATOM 4217 C CB  . VAL D 1 86  ? -32.005 47.580  155.052 1.00 31.99  ? 86  VAL D CB  1 
ATOM 4218 C CG1 . VAL D 1 86  ? -33.054 47.683  153.960 1.00 31.99  ? 86  VAL D CG1 1 
ATOM 4219 C CG2 . VAL D 1 86  ? -32.135 46.263  155.796 1.00 31.99  ? 86  VAL D CG2 1 
ATOM 4220 N N   . SER D 1 87  ? -30.300 50.186  154.179 1.00 31.73  ? 87  SER D N   1 
ATOM 4221 C CA  . SER D 1 87  ? -30.233 51.447  153.405 1.00 31.73  ? 87  SER D CA  1 
ATOM 4222 C C   . SER D 1 87  ? -29.004 51.425  152.503 1.00 31.73  ? 87  SER D C   1 
ATOM 4223 O O   . SER D 1 87  ? -29.148 51.748  151.322 1.00 31.73  ? 87  SER D O   1 
ATOM 4224 C CB  . SER D 1 87  ? -30.234 52.638  154.309 1.00 30.00  ? 87  SER D CB  1 
ATOM 4225 O OG  . SER D 1 87  ? -29.056 52.692  155.096 1.00 30.00  ? 87  SER D OG  1 
ATOM 4226 N N   . TYR D 1 88  ? -27.846 51.025  153.020 1.00 27.26  ? 88  TYR D N   1 
ATOM 4227 C CA  . TYR D 1 88  ? -26.584 51.024  152.246 1.00 27.26  ? 88  TYR D CA  1 
ATOM 4228 C C   . TYR D 1 88  ? -26.781 50.173  151.001 1.00 27.26  ? 88  TYR D C   1 
ATOM 4229 O O   . TYR D 1 88  ? -26.418 50.626  149.909 1.00 27.26  ? 88  TYR D O   1 
ATOM 4230 C CB  . TYR D 1 88  ? -25.430 50.479  153.081 1.00 27.26  ? 88  TYR D CB  1 
ATOM 4231 C CG  . TYR D 1 88  ? -24.099 50.468  152.377 1.00 27.26  ? 88  TYR D CG  1 
ATOM 4232 C CD1 . TYR D 1 88  ? -23.788 49.488  151.454 1.00 27.26  ? 88  TYR D CD1 1 
ATOM 4233 C CD2 . TYR D 1 88  ? -23.149 51.438  152.639 1.00 27.26  ? 88  TYR D CD2 1 
ATOM 4234 C CE1 . TYR D 1 88  ? -22.567 49.471  150.803 1.00 27.26  ? 88  TYR D CE1 1 
ATOM 4235 C CE2 . TYR D 1 88  ? -21.922 51.436  152.000 1.00 27.26  ? 88  TYR D CE2 1 
ATOM 4236 C CZ  . TYR D 1 88  ? -21.629 50.449  151.077 1.00 27.26  ? 88  TYR D CZ  1 
ATOM 4237 O OH  . TYR D 1 88  ? -20.423 50.441  150.442 1.00 27.26  ? 88  TYR D OH  1 
ATOM 4238 N N   . VAL D 1 89  ? -27.367 48.993  151.152 1.00 25.71  ? 89  VAL D N   1 
ATOM 4239 C CA  . VAL D 1 89  ? -27.541 48.046  150.019 1.00 25.71  ? 89  VAL D CA  1 
ATOM 4240 C C   . VAL D 1 89  ? -28.550 48.619  149.033 1.00 25.71  ? 89  VAL D C   1 
ATOM 4241 O O   . VAL D 1 89  ? -28.250 48.617  147.837 1.00 25.71  ? 89  VAL D O   1 
ATOM 4242 C CB  . VAL D 1 89  ? -27.994 46.667  150.522 1.00 25.71  ? 89  VAL D CB  1 
ATOM 4243 C CG1 . VAL D 1 89  ? -28.330 45.732  149.374 1.00 25.71  ? 89  VAL D CG1 1 
ATOM 4244 C CG2 . VAL D 1 89  ? -26.960 46.041  151.440 1.00 25.71  ? 89  VAL D CG2 1 
ATOM 4245 N N   . ASN D 1 90  ? -29.684 49.117  149.507 1.00 26.29  ? 90  ASN D N   1 
ATOM 4246 C CA  . ASN D 1 90  ? -30.774 49.587  148.618 1.00 26.29  ? 90  ASN D CA  1 
ATOM 4247 C C   . ASN D 1 90  ? -30.463 50.977  148.076 1.00 26.29  ? 90  ASN D C   1 
ATOM 4248 O O   . ASN D 1 90  ? -31.256 51.459  147.263 1.00 26.29  ? 90  ASN D O   1 
ATOM 4249 C CB  . ASN D 1 90  ? -32.113 49.580  149.350 1.00 26.29  ? 90  ASN D CB  1 
ATOM 4250 C CG  . ASN D 1 90  ? -32.527 48.200  149.806 1.00 26.29  ? 90  ASN D CG  1 
ATOM 4251 O OD1 . ASN D 1 90  ? -32.173 47.204  149.181 1.00 26.29  ? 90  ASN D OD1 1 
ATOM 4252 N ND2 . ASN D 1 90  ? -33.283 48.132  150.888 1.00 26.29  ? 90  ASN D ND2 1 
ATOM 4253 N N   . THR D 1 91  ? -29.364 51.599  148.494 1.00 24.37  ? 91  THR D N   1 
ATOM 4254 C CA  . THR D 1 91  ? -29.001 52.971  148.066 1.00 24.37  ? 91  THR D CA  1 
ATOM 4255 C C   . THR D 1 91  ? -27.663 52.965  147.344 1.00 24.37  ? 91  THR D C   1 
ATOM 4256 O O   . THR D 1 91  ? -27.664 53.177  146.127 1.00 24.37  ? 91  THR D O   1 
ATOM 4257 C CB  . THR D 1 91  ? -28.911 53.924  149.257 1.00 24.37  ? 91  THR D CB  1 
ATOM 4258 O OG1 . THR D 1 91  ? -30.216 54.045  149.821 1.00 24.37  ? 91  THR D OG1 1 
ATOM 4259 C CG2 . THR D 1 91  ? -28.385 55.288  148.874 1.00 24.37  ? 91  THR D CG2 1 
ATOM 4260 N N   . ASN D 1 92  ? -26.564 52.738  148.057 1.00 22.65  ? 92  ASN D N   1 
ATOM 4261 C CA  . ASN D 1 92  ? -25.208 52.813  147.465 1.00 22.65  ? 92  ASN D CA  1 
ATOM 4262 C C   . ASN D 1 92  ? -25.048 51.720  146.414 1.00 22.65  ? 92  ASN D C   1 
ATOM 4263 O O   . ASN D 1 92  ? -24.809 52.062  145.245 1.00 22.65  ? 92  ASN D O   1 
ATOM 4264 C CB  . ASN D 1 92  ? -24.128 52.692  148.533 1.00 22.65  ? 92  ASN D CB  1 
ATOM 4265 C CG  . ASN D 1 92  ? -22.731 52.906  147.991 1.00 22.65  ? 92  ASN D CG  1 
ATOM 4266 O OD1 . ASN D 1 92  ? -22.499 52.788  146.792 1.00 22.65  ? 92  ASN D OD1 1 
ATOM 4267 N ND2 . ASN D 1 92  ? -21.799 53.238  148.867 1.00 22.65  ? 92  ASN D ND2 1 
ATOM 4268 N N   . MET D 1 93  ? -25.207 50.463  146.800 1.00 20.89  ? 93  MET D N   1 
ATOM 4269 C CA  . MET D 1 93  ? -25.025 49.322  145.875 1.00 20.89  ? 93  MET D CA  1 
ATOM 4270 C C   . MET D 1 93  ? -26.083 49.406  144.784 1.00 20.89  ? 93  MET D C   1 
ATOM 4271 O O   . MET D 1 93  ? -25.776 49.056  143.642 1.00 20.89  ? 93  MET D O   1 
ATOM 4272 C CB  . MET D 1 93  ? -25.165 47.998  146.620 1.00 20.89  ? 93  MET D CB  1 
ATOM 4273 C CG  . MET D 1 93  ? -24.073 47.768  147.634 1.00 20.89  ? 93  MET D CG  1 
ATOM 4274 S SD  . MET D 1 93  ? -24.023 46.056  148.191 1.00 20.89  ? 93  MET D SD  1 
ATOM 4275 C CE  . MET D 1 93  ? -22.401 46.017  148.949 1.00 20.89  ? 93  MET D CE  1 
ATOM 4276 N N   . GLY D 1 94  ? -27.276 49.880  145.120 1.00 17.37  ? 94  GLY D N   1 
ATOM 4277 C CA  . GLY D 1 94  ? -28.381 49.975  144.155 1.00 17.37  ? 94  GLY D CA  1 
ATOM 4278 C C   . GLY D 1 94  ? -28.023 50.860  142.986 1.00 17.37  ? 94  GLY D C   1 
ATOM 4279 O O   . GLY D 1 94  ? -28.282 50.448  141.855 1.00 17.37  ? 94  GLY D O   1 
ATOM 4280 N N   . LEU D 1 95  ? -27.438 52.029  143.228 1.00 16.07  ? 95  LEU D N   1 
ATOM 4281 C CA  . LEU D 1 95  ? -27.131 52.983  142.139 1.00 16.07  ? 95  LEU D CA  1 
ATOM 4282 C C   . LEU D 1 95  ? -26.230 52.274  141.140 1.00 16.07  ? 95  LEU D C   1 
ATOM 4283 O O   . LEU D 1 95  ? -26.470 52.418  139.937 1.00 16.07  ? 95  LEU D O   1 
ATOM 4284 C CB  . LEU D 1 95  ? -26.437 54.225  142.692 1.00 16.07  ? 95  LEU D CB  1 
ATOM 4285 C CG  . LEU D 1 95  ? -26.110 55.296  141.655 1.00 16.07  ? 95  LEU D CG  1 
ATOM 4286 C CD1 . LEU D 1 95  ? -27.341 55.657  140.840 1.00 16.07  ? 95  LEU D CD1 1 
ATOM 4287 C CD2 . LEU D 1 95  ? -25.532 56.531  142.318 1.00 16.07  ? 95  LEU D CD2 1 
ATOM 4288 N N   . LYS D 1 96  ? -25.252 51.520  141.622 1.00 15.70  ? 96  LYS D N   1 
ATOM 4289 C CA  . LYS D 1 96  ? -24.297 50.815  140.739 1.00 15.70  ? 96  LYS D CA  1 
ATOM 4290 C C   . LYS D 1 96  ? -25.064 49.804  139.893 1.00 15.70  ? 96  LYS D C   1 
ATOM 4291 O O   . LYS D 1 96  ? -24.826 49.769  138.684 1.00 15.70  ? 96  LYS D O   1 
ATOM 4292 C CB  . LYS D 1 96  ? -23.221 50.135  141.580 1.00 15.70  ? 96  LYS D CB  1 
ATOM 4293 C CG  . LYS D 1 96  ? -22.311 51.076  142.353 1.00 15.70  ? 96  LYS D CG  1 
ATOM 4294 C CD  . LYS D 1 96  ? -21.334 50.351  143.239 1.00 15.70  ? 96  LYS D CD  1 
ATOM 4295 C CE  . LYS D 1 96  ? -20.359 51.280  143.924 1.00 15.70  ? 96  LYS D CE  1 
ATOM 4296 N NZ  . LYS D 1 96  ? -19.435 51.904  142.950 1.00 15.70  ? 96  LYS D NZ  1 
ATOM 4297 N N   . PHE D 1 97  ? -25.964 49.032  140.492 1.00 14.36  ? 97  PHE D N   1 
ATOM 4298 C CA  . PHE D 1 97  ? -26.746 47.993  139.780 1.00 14.36  ? 97  PHE D CA  1 
ATOM 4299 C C   . PHE D 1 97  ? -27.623 48.669  138.743 1.00 14.36  ? 97  PHE D C   1 
ATOM 4300 O O   . PHE D 1 97  ? -27.719 48.157  137.627 1.00 14.36  ? 97  PHE D O   1 
ATOM 4301 C CB  . PHE D 1 97  ? -27.597 47.191  140.761 1.00 30.00  ? 97  PHE D CB  1 
ATOM 4302 C CG  . PHE D 1 97  ? -28.423 46.085  140.159 1.00 30.00  ? 97  PHE D CG  1 
ATOM 4303 C CD1 . PHE D 1 97  ? -27.847 45.129  139.342 1.00 30.00  ? 97  PHE D CD1 1 
ATOM 4304 C CD2 . PHE D 1 97  ? -29.774 45.981  140.444 1.00 30.00  ? 97  PHE D CD2 1 
ATOM 4305 C CE1 . PHE D 1 97  ? -28.609 44.106  138.801 1.00 30.00  ? 97  PHE D CE1 1 
ATOM 4306 C CE2 . PHE D 1 97  ? -30.534 44.958  139.906 1.00 30.00  ? 97  PHE D CE2 1 
ATOM 4307 C CZ  . PHE D 1 97  ? -29.949 44.022  139.086 1.00 30.00  ? 97  PHE D CZ  1 
ATOM 4308 N N   . ARG D 1 98  ? -28.228 49.796  139.094 1.00 13.90  ? 98  ARG D N   1 
ATOM 4309 C CA  . ARG D 1 98  ? -29.142 50.518  138.184 1.00 13.90  ? 98  ARG D CA  1 
ATOM 4310 C C   . ARG D 1 98  ? -28.351 50.943  136.954 1.00 13.90  ? 98  ARG D C   1 
ATOM 4311 O O   . ARG D 1 98  ? -28.864 50.766  135.845 1.00 13.90  ? 98  ARG D O   1 
ATOM 4312 C CB  . ARG D 1 98  ? -29.771 51.695  138.925 1.00 13.90  ? 98  ARG D CB  1 
ATOM 4313 C CG  . ARG D 1 98  ? -30.783 51.281  139.980 1.00 13.90  ? 98  ARG D CG  1 
ATOM 4314 C CD  . ARG D 1 98  ? -30.981 52.392  140.982 1.00 13.90  ? 98  ARG D CD  1 
ATOM 4315 N NE  . ARG D 1 98  ? -31.373 53.625  140.323 1.00 13.90  ? 98  ARG D NE  1 
ATOM 4316 C CZ  . ARG D 1 98  ? -31.238 54.837  140.845 1.00 13.90  ? 98  ARG D CZ  1 
ATOM 4317 N NH1 . ARG D 1 98  ? -30.705 54.996  142.044 1.00 13.90  ? 98  ARG D NH1 1 
ATOM 4318 N NH2 . ARG D 1 98  ? -31.626 55.893  140.158 1.00 13.90  ? 98  ARG D NH2 1 
ATOM 4319 N N   . GLN D 1 99  ? -27.130 51.428  137.135 1.00 12.83  ? 99  GLN D N   1 
ATOM 4320 C CA  . GLN D 1 99  ? -26.292 51.907  136.013 1.00 12.83  ? 99  GLN D CA  1 
ATOM 4321 C C   . GLN D 1 99  ? -25.987 50.743  135.076 1.00 12.83  ? 99  GLN D C   1 
ATOM 4322 O O   . GLN D 1 99  ? -26.159 50.916  133.866 1.00 12.83  ? 99  GLN D O   1 
ATOM 4323 C CB  . GLN D 1 99  ? -25.017 52.534  136.557 1.00 12.83  ? 99  GLN D CB  1 
ATOM 4324 C CG  . GLN D 1 99  ? -24.127 53.130  135.482 1.00 12.83  ? 99  GLN D CG  1 
ATOM 4325 C CD  . GLN D 1 99  ? -23.001 53.932  136.085 1.00 12.83  ? 99  GLN D CD  1 
ATOM 4326 O OE1 . GLN D 1 99  ? -23.076 54.380  137.226 1.00 12.83  ? 99  GLN D OE1 1 
ATOM 4327 N NE2 . GLN D 1 99  ? -21.944 54.121  135.313 1.00 12.83  ? 99  GLN D NE2 1 
ATOM 4328 N N   . LEU D 1 100 ? -25.580 49.593  135.602 1.00 12.19  ? 100 LEU D N   1 
ATOM 4329 C CA  . LEU D 1 100 ? -25.189 48.440  134.753 1.00 12.19  ? 100 LEU D CA  1 
ATOM 4330 C C   . LEU D 1 100 ? -26.420 47.917  134.025 1.00 12.19  ? 100 LEU D C   1 
ATOM 4331 O O   . LEU D 1 100 ? -26.321 47.671  132.819 1.00 12.19  ? 100 LEU D O   1 
ATOM 4332 C CB  . LEU D 1 100 ? -24.558 47.346  135.613 1.00 12.19  ? 100 LEU D CB  1 
ATOM 4333 C CG  . LEU D 1 100 ? -24.034 46.142  134.837 1.00 12.19  ? 100 LEU D CG  1 
ATOM 4334 C CD1 . LEU D 1 100 ? -22.763 45.605  135.465 1.00 12.19  ? 100 LEU D CD1 1 
ATOM 4335 C CD2 . LEU D 1 100 ? -25.087 45.052  134.746 1.00 12.19  ? 100 LEU D CD2 1 
ATOM 4336 N N   . LEU D 1 101 ? -27.535 47.755  134.724 1.00 13.00  ? 101 LEU D N   1 
ATOM 4337 C CA  . LEU D 1 101 ? -28.778 47.255  134.102 1.00 13.00  ? 101 LEU D CA  1 
ATOM 4338 C C   . LEU D 1 101 ? -29.098 48.152  132.914 1.00 13.00  ? 101 LEU D C   1 
ATOM 4339 O O   . LEU D 1 101 ? -29.344 47.613  131.834 1.00 13.00  ? 101 LEU D O   1 
ATOM 4340 C CB  . LEU D 1 101 ? -29.913 47.268  135.124 1.00 13.00  ? 101 LEU D CB  1 
ATOM 4341 C CG  . LEU D 1 101 ? -30.123 45.980  135.914 1.00 13.00  ? 101 LEU D CG  1 
ATOM 4342 C CD1 . LEU D 1 101 ? -31.307 46.123  136.853 1.00 13.00  ? 101 LEU D CD1 1 
ATOM 4343 C CD2 . LEU D 1 101 ? -30.329 44.796  134.987 1.00 13.00  ? 101 LEU D CD2 1 
ATOM 4344 N N   . TRP D 1 102 ? -29.056 49.468  133.086 1.00 11.41  ? 102 TRP D N   1 
ATOM 4345 C CA  . TRP D 1 102 ? -29.419 50.413  132.007 1.00 11.41  ? 102 TRP D CA  1 
ATOM 4346 C C   . TRP D 1 102 ? -28.528 50.158  130.802 1.00 11.41  ? 102 TRP D C   1 
ATOM 4347 O O   . TRP D 1 102 ? -29.071 49.952  129.718 1.00 11.41  ? 102 TRP D O   1 
ATOM 4348 C CB  . TRP D 1 102 ? -29.301 51.857  132.485 1.00 11.41  ? 102 TRP D CB  1 
ATOM 4349 C CG  . TRP D 1 102 ? -29.532 52.877  131.419 1.00 11.41  ? 102 TRP D CG  1 
ATOM 4350 C CD1 . TRP D 1 102 ? -30.719 53.447  131.068 1.00 11.41  ? 102 TRP D CD1 1 
ATOM 4351 C CD2 . TRP D 1 102 ? -28.539 53.458  130.559 1.00 11.41  ? 102 TRP D CD2 1 
ATOM 4352 N NE1 . TRP D 1 102 ? -30.533 54.340  130.048 1.00 11.41  ? 102 TRP D NE1 1 
ATOM 4353 C CE2 . TRP D 1 102 ? -29.205 54.368  129.716 1.00 11.41  ? 102 TRP D CE2 1 
ATOM 4354 C CE3 . TRP D 1 102 ? -27.158 53.297  130.422 1.00 11.41  ? 102 TRP D CE3 1 
ATOM 4355 C CZ2 . TRP D 1 102 ? -28.533 55.113  128.751 1.00 11.41  ? 102 TRP D CZ2 1 
ATOM 4356 C CZ3 . TRP D 1 102 ? -26.495 54.033  129.466 1.00 11.41  ? 102 TRP D CZ3 1 
ATOM 4357 C CH2 . TRP D 1 102 ? -27.175 54.927  128.643 1.00 11.41  ? 102 TRP D CH2 1 
ATOM 4358 N N   . PHE D 1 103 ? -27.216 50.122  130.983 1.00 11.40  ? 103 PHE D N   1 
ATOM 4359 C CA  . PHE D 1 103 ? -26.265 49.979  129.860 1.00 11.40  ? 103 PHE D CA  1 
ATOM 4360 C C   . PHE D 1 103 ? -26.584 48.717  129.078 1.00 11.40  ? 103 PHE D C   1 
ATOM 4361 O O   . PHE D 1 103 ? -26.769 48.821  127.863 1.00 11.40  ? 103 PHE D O   1 
ATOM 4362 C CB  . PHE D 1 103 ? -24.828 49.929  130.367 1.00 11.40  ? 103 PHE D CB  1 
ATOM 4363 C CG  . PHE D 1 103 ? -23.784 49.807  129.290 1.00 11.40  ? 103 PHE D CG  1 
ATOM 4364 C CD1 . PHE D 1 103 ? -23.367 50.919  128.581 1.00 11.40  ? 103 PHE D CD1 1 
ATOM 4365 C CD2 . PHE D 1 103 ? -23.212 48.582  128.995 1.00 11.40  ? 103 PHE D CD2 1 
ATOM 4366 C CE1 . PHE D 1 103 ? -22.404 50.806  127.593 1.00 11.40  ? 103 PHE D CE1 1 
ATOM 4367 C CE2 . PHE D 1 103 ? -22.249 48.471  128.006 1.00 11.40  ? 103 PHE D CE2 1 
ATOM 4368 C CZ  . PHE D 1 103 ? -21.848 49.583  127.308 1.00 11.40  ? 103 PHE D CZ  1 
ATOM 4369 N N   . HIS D 1 104 ? -26.681 47.570  129.736 1.00 11.87  ? 104 HIS D N   1 
ATOM 4370 C CA  . HIS D 1 104 ? -26.871 46.275  129.035 1.00 11.87  ? 104 HIS D CA  1 
ATOM 4371 C C   . HIS D 1 104 ? -28.266 46.200  128.423 1.00 11.87  ? 104 HIS D C   1 
ATOM 4372 O O   . HIS D 1 104 ? -28.361 45.795  127.262 1.00 11.87  ? 104 HIS D O   1 
ATOM 4373 C CB  . HIS D 1 104 ? -26.570 45.117  129.983 1.00 11.87  ? 104 HIS D CB  1 
ATOM 4374 C CG  . HIS D 1 104 ? -25.125 44.985  130.312 1.00 11.87  ? 104 HIS D CG  1 
ATOM 4375 N ND1 . HIS D 1 104 ? -24.651 45.075  131.601 1.00 11.87  ? 104 HIS D ND1 1 
ATOM 4376 C CD2 . HIS D 1 104 ? -24.048 44.783  129.525 1.00 11.87  ? 104 HIS D CD2 1 
ATOM 4377 C CE1 . HIS D 1 104 ? -23.344 44.926  131.597 1.00 11.87  ? 104 HIS D CE1 1 
ATOM 4378 N NE2 . HIS D 1 104 ? -22.951 44.746  130.337 1.00 11.87  ? 104 HIS D NE2 1 
ATOM 4379 N N   . ILE D 1 105 ? -29.304 46.585  129.154 1.00 12.67  ? 105 ILE D N   1 
ATOM 4380 C CA  . ILE D 1 105 ? -30.704 46.480  128.659 1.00 12.67  ? 105 ILE D CA  1 
ATOM 4381 C C   . ILE D 1 105 ? -30.842 47.432  127.480 1.00 12.67  ? 105 ILE D C   1 
ATOM 4382 O O   . ILE D 1 105 ? -31.556 47.083  126.545 1.00 12.67  ? 105 ILE D O   1 
ATOM 4383 C CB  . ILE D 1 105 ? -31.728 46.774  129.765 1.00 12.67  ? 105 ILE D CB  1 
ATOM 4384 C CG1 . ILE D 1 105 ? -31.640 45.756  130.903 1.00 12.67  ? 105 ILE D CG1 1 
ATOM 4385 C CG2 . ILE D 1 105 ? -33.129 46.841  129.185 1.00 12.67  ? 105 ILE D CG2 1 
ATOM 4386 C CD1 . ILE D 1 105 ? -32.453 46.126  132.119 1.00 12.67  ? 105 ILE D CD1 1 
ATOM 4387 N N   . SER D 1 106 ? -30.163 48.570  127.509 1.00 11.80  ? 106 SER D N   1 
ATOM 4388 C CA  . SER D 1 106 ? -30.226 49.586  126.434 1.00 11.80  ? 106 SER D CA  1 
ATOM 4389 C C   . SER D 1 106 ? -29.366 49.141  125.261 1.00 11.80  ? 106 SER D C   1 
ATOM 4390 O O   . SER D 1 106 ? -29.699 49.488  124.139 1.00 11.80  ? 106 SER D O   1 
ATOM 4391 C CB  . SER D 1 106 ? -29.789 50.914  126.941 1.00 11.80  ? 106 SER D CB  1 
ATOM 4392 O OG  . SER D 1 106 ? -30.633 51.355  127.991 1.00 11.80  ? 106 SER D OG  1 
ATOM 4393 N N   . CYS D 1 107 ? -28.279 48.428  125.516 1.00 12.09  ? 107 CYS D N   1 
ATOM 4394 C CA  . CYS D 1 107 ? -27.366 47.959  124.452 1.00 12.09  ? 107 CYS D CA  1 
ATOM 4395 C C   . CYS D 1 107 ? -28.019 46.782  123.744 1.00 12.09  ? 107 CYS D C   1 
ATOM 4396 O O   . CYS D 1 107 ? -27.694 46.550  122.581 1.00 12.09  ? 107 CYS D O   1 
ATOM 4397 C CB  . CYS D 1 107 ? -26.013 47.547  125.008 1.00 12.09  ? 107 CYS D CB  1 
ATOM 4398 S SG  . CYS D 1 107 ? -24.928 48.945  125.382 1.00 12.09  ? 107 CYS D SG  1 
ATOM 4399 N N   . LEU D 1 108 ? -28.914 46.075  124.419 1.00 12.64  ? 108 LEU D N   1 
ATOM 4400 C CA  . LEU D 1 108 ? -29.555 44.872  123.845 1.00 12.64  ? 108 LEU D CA  1 
ATOM 4401 C C   . LEU D 1 108 ? -30.750 45.309  123.006 1.00 12.64  ? 108 LEU D C   1 
ATOM 4402 O O   . LEU D 1 108 ? -30.966 44.688  121.964 1.00 12.64  ? 108 LEU D O   1 
ATOM 4403 C CB  . LEU D 1 108 ? -29.977 43.924  124.965 1.00 12.64  ? 108 LEU D CB  1 
ATOM 4404 C CG  . LEU D 1 108 ? -28.879 43.015  125.507 1.00 12.64  ? 108 LEU D CG  1 
ATOM 4405 C CD1 . LEU D 1 108 ? -29.327 42.336  126.788 1.00 12.64  ? 108 LEU D CD1 1 
ATOM 4406 C CD2 . LEU D 1 108 ? -28.469 41.983  124.475 1.00 12.64  ? 108 LEU D CD2 1 
ATOM 4407 N N   . THR D 1 109 ? -31.496 46.331  123.422 1.00 12.81  ? 109 THR D N   1 
ATOM 4408 C CA  . THR D 1 109 ? -32.596 46.803  122.578 1.00 12.81  ? 109 THR D CA  1 
ATOM 4409 C C   . THR D 1 109 ? -32.144 47.781  121.493 1.00 12.81  ? 109 THR D C   1 
ATOM 4410 O O   . THR D 1 109 ? -32.425 47.570  120.307 1.00 12.81  ? 109 THR D O   1 
ATOM 4411 C CB  . THR D 1 109 ? -33.694 47.431  123.446 1.00 12.81  ? 109 THR D CB  1 
ATOM 4412 O OG1 . THR D 1 109 ? -34.771 47.871  122.611 1.00 12.81  ? 109 THR D OG1 1 
ATOM 4413 C CG2 . THR D 1 109 ? -33.177 48.612  124.238 1.00 12.81  ? 109 THR D CG2 1 
ATOM 4414 N N   . PHE D 1 110 ? -31.450 48.859  121.867 1.00 13.04  ? 110 PHE D N   1 
ATOM 4415 C CA  . PHE D 1 110 ? -30.978 49.841  120.892 1.00 13.04  ? 110 PHE D CA  1 
ATOM 4416 C C   . PHE D 1 110 ? -29.732 49.416  120.122 1.00 13.04  ? 110 PHE D C   1 
ATOM 4417 O O   . PHE D 1 110 ? -29.575 49.813  118.962 1.00 13.04  ? 110 PHE D O   1 
ATOM 4418 C CB  . PHE D 1 110 ? -30.759 51.182  121.590 1.00 13.04  ? 110 PHE D CB  1 
ATOM 4419 C CG  . PHE D 1 110 ? -31.976 51.666  122.320 1.00 13.04  ? 110 PHE D CG  1 
ATOM 4420 C CD1 . PHE D 1 110 ? -33.105 52.049  121.615 1.00 13.04  ? 110 PHE D CD1 1 
ATOM 4421 C CD2 . PHE D 1 110 ? -32.000 51.733  123.701 1.00 13.04  ? 110 PHE D CD2 1 
ATOM 4422 C CE1 . PHE D 1 110 ? -34.234 52.485  122.272 1.00 13.04  ? 110 PHE D CE1 1 
ATOM 4423 C CE2 . PHE D 1 110 ? -33.132 52.166  124.365 1.00 13.04  ? 110 PHE D CE2 1 
ATOM 4424 C CZ  . PHE D 1 110 ? -34.251 52.540  123.648 1.00 13.04  ? 110 PHE D CZ  1 
ATOM 4425 N N   . GLY D 1 111 ? -28.846 48.628  120.720 1.00 12.37  ? 111 GLY D N   1 
ATOM 4426 C CA  . GLY D 1 111 ? -27.544 48.392  120.123 1.00 12.37  ? 111 GLY D CA  1 
ATOM 4427 C C   . GLY D 1 111 ? -26.425 49.236  120.707 1.00 12.37  ? 111 GLY D C   1 
ATOM 4428 O O   . GLY D 1 111 ? -26.591 50.427  120.987 1.00 12.37  ? 111 GLY D O   1 
ATOM 4429 N N   . ARG D 1 112 ? -25.294 48.566  120.948 1.00 13.35  ? 112 ARG D N   1 
ATOM 4430 C CA  . ARG D 1 112 ? -24.128 49.160  121.641 1.00 13.35  ? 112 ARG D CA  1 
ATOM 4431 C C   . ARG D 1 112 ? -23.747 50.503  121.055 1.00 13.35  ? 112 ARG D C   1 
ATOM 4432 O O   . ARG D 1 112 ? -23.699 51.463  121.811 1.00 13.35  ? 112 ARG D O   1 
ATOM 4433 C CB  . ARG D 1 112 ? -22.935 48.215  121.522 1.00 13.35  ? 112 ARG D CB  1 
ATOM 4434 C CG  . ARG D 1 112 ? -21.936 48.330  122.662 1.00 13.35  ? 112 ARG D CG  1 
ATOM 4435 C CD  . ARG D 1 112 ? -20.826 47.314  122.504 1.00 13.35  ? 112 ARG D CD  1 
ATOM 4436 N NE  . ARG D 1 112 ? -20.284 47.369  121.157 1.00 13.35  ? 112 ARG D NE  1 
ATOM 4437 C CZ  . ARG D 1 112 ? -19.465 48.312  120.710 1.00 13.35  ? 112 ARG D CZ  1 
ATOM 4438 N NH1 . ARG D 1 112 ? -19.079 49.295  121.505 1.00 13.35  ? 112 ARG D NH1 1 
ATOM 4439 N NH2 . ARG D 1 112 ? -19.036 48.272  119.463 1.00 13.35  ? 112 ARG D NH2 1 
ATOM 4440 N N   . GLU D 1 113 ? -23.441 50.555  119.775 1.00 14.08  ? 113 GLU D N   1 
ATOM 4441 C CA  . GLU D 1 113 ? -22.962 51.797  119.169 1.00 14.08  ? 113 GLU D CA  1 
ATOM 4442 C C   . GLU D 1 113 ? -23.975 52.922  119.331 1.00 14.08  ? 113 GLU D C   1 
ATOM 4443 O O   . GLU D 1 113 ? -23.602 54.086  119.538 1.00 14.08  ? 113 GLU D O   1 
ATOM 4444 C CB  . GLU D 1 113 ? -22.651 51.569  117.690 1.00 14.08  ? 113 GLU D CB  1 
ATOM 4445 C CG  . GLU D 1 113 ? -21.484 50.623  117.434 1.00 14.08  ? 113 GLU D CG  1 
ATOM 4446 C CD  . GLU D 1 113 ? -21.882 49.158  117.496 1.00 14.08  ? 113 GLU D CD  1 
ATOM 4447 O OE1 . GLU D 1 113 ? -23.083 48.868  117.676 1.00 14.08  ? 113 GLU D OE1 1 
ATOM 4448 O OE2 . GLU D 1 113 ? -20.990 48.295  117.365 1.00 14.08  ? 113 GLU D OE2 1 
ATOM 4449 N N   . THR D 1 114 ? -25.262 52.589  119.256 1.00 12.49  ? 114 THR D N   1 
ATOM 4450 C CA  . THR D 1 114 ? -26.300 53.573  119.531 1.00 12.49  ? 114 THR D CA  1 
ATOM 4451 C C   . THR D 1 114 ? -26.176 54.118  120.946 1.00 12.49  ? 114 THR D C   1 
ATOM 4452 O O   . THR D 1 114 ? -26.317 55.324  121.168 1.00 12.49  ? 114 THR D O   1 
ATOM 4453 C CB  . THR D 1 114 ? -27.680 52.955  119.314 1.00 12.49  ? 114 THR D CB  1 
ATOM 4454 O OG1 . THR D 1 114 ? -27.681 52.194  118.101 1.00 12.49  ? 114 THR D OG1 1 
ATOM 4455 C CG2 . THR D 1 114 ? -28.743 54.041  119.226 1.00 12.49  ? 114 THR D CG2 1 
ATOM 4456 N N   . VAL D 1 115 ? -25.894 53.247  121.918 1.00 12.39  ? 115 VAL D N   1 
ATOM 4457 C CA  . VAL D 1 115 ? -25.748 53.698  123.299 1.00 12.39  ? 115 VAL D CA  1 
ATOM 4458 C C   . VAL D 1 115 ? -24.517 54.585  123.472 1.00 12.39  ? 115 VAL D C   1 
ATOM 4459 O O   . VAL D 1 115 ? -24.560 55.574  124.208 1.00 12.39  ? 115 VAL D O   1 
ATOM 4460 C CB  . VAL D 1 115 ? -25.708 52.482  124.244 1.00 12.39  ? 115 VAL D CB  1 
ATOM 4461 C CG1 . VAL D 1 115 ? -25.496 52.923  125.687 1.00 12.39  ? 115 VAL D CG1 1 
ATOM 4462 C CG2 . VAL D 1 115 ? -26.987 51.669  124.116 1.00 12.39  ? 115 VAL D CG2 1 
ATOM 4463 N N   . ILE D 1 116 ? -23.396 54.251  122.826 1.00 13.36  ? 116 ILE D N   1 
ATOM 4464 C CA  . ILE D 1 116 ? -22.225 55.124  122.933 1.00 13.36  ? 116 ILE D CA  1 
ATOM 4465 C C   . ILE D 1 116 ? -22.470 56.497  122.311 1.00 13.36  ? 116 ILE D C   1 
ATOM 4466 O O   . ILE D 1 116 ? -22.118 57.531  122.904 1.00 13.36  ? 116 ILE D O   1 
ATOM 4467 C CB  . ILE D 1 116 ? -21.003 54.461  122.270 1.00 30.00  ? 116 ILE D CB  1 
ATOM 4468 C CG1 . ILE D 1 116 ? -20.598 53.201  123.038 1.00 30.00  ? 116 ILE D CG1 1 
ATOM 4469 C CG2 . ILE D 1 116 ? -19.840 55.439  122.194 1.00 30.00  ? 116 ILE D CG2 1 
ATOM 4470 C CD1 . ILE D 1 116 ? -19.582 52.346  122.315 1.00 30.00  ? 116 ILE D CD1 1 
ATOM 4471 N N   . GLU D 1 117 ? -23.075 56.536  121.121 1.00 14.11  ? 117 GLU D N   1 
ATOM 4472 C CA  . GLU D 1 117 ? -23.415 57.825  120.520 1.00 14.11  ? 117 GLU D CA  1 
ATOM 4473 C C   . GLU D 1 117 ? -24.417 58.595  121.373 1.00 14.11  ? 117 GLU D C   1 
ATOM 4474 O O   . GLU D 1 117 ? -24.324 59.823  121.498 1.00 14.11  ? 117 GLU D O   1 
ATOM 4475 C CB  . GLU D 1 117 ? -23.961 57.617  119.110 1.00 14.11  ? 117 GLU D CB  1 
ATOM 4476 C CG  . GLU D 1 117 ? -22.918 57.124  118.120 1.00 14.11  ? 117 GLU D CG  1 
ATOM 4477 C CD  . GLU D 1 117 ? -21.835 58.150  117.850 1.00 14.11  ? 117 GLU D CD  1 
ATOM 4478 O OE1 . GLU D 1 117 ? -22.132 59.362  117.903 1.00 14.11  ? 117 GLU D OE1 1 
ATOM 4479 O OE2 . GLU D 1 117 ? -20.681 57.744  117.596 1.00 14.11  ? 117 GLU D OE2 1 
ATOM 4480 N N   . TYR D 1 118 ? -25.355 57.888  122.003 1.00 12.40  ? 118 TYR D N   1 
ATOM 4481 C CA  . TYR D 1 118 ? -26.281 58.530  122.929 1.00 12.40  ? 118 TYR D CA  1 
ATOM 4482 C C   . TYR D 1 118 ? -25.545 59.143  124.109 1.00 12.40  ? 118 TYR D C   1 
ATOM 4483 O O   . TYR D 1 118 ? -25.849 60.261  124.530 1.00 12.40  ? 118 TYR D O   1 
ATOM 4484 C CB  . TYR D 1 118 ? -27.316 57.520  123.419 1.00 12.40  ? 118 TYR D CB  1 
ATOM 4485 C CG  . TYR D 1 118 ? -28.247 58.091  124.460 1.00 12.40  ? 118 TYR D CG  1 
ATOM 4486 C CD1 . TYR D 1 118 ? -29.250 58.979  124.105 1.00 12.40  ? 118 TYR D CD1 1 
ATOM 4487 C CD2 . TYR D 1 118 ? -28.102 57.766  125.801 1.00 12.40  ? 118 TYR D CD2 1 
ATOM 4488 C CE1 . TYR D 1 118 ? -30.095 59.513  125.051 1.00 12.40  ? 118 TYR D CE1 1 
ATOM 4489 C CE2 . TYR D 1 118 ? -28.943 58.298  126.756 1.00 12.40  ? 118 TYR D CE2 1 
ATOM 4490 C CZ  . TYR D 1 118 ? -29.938 59.172  126.374 1.00 12.40  ? 118 TYR D CZ  1 
ATOM 4491 O OH  . TYR D 1 118 ? -30.782 59.707  127.318 1.00 12.40  ? 118 TYR D OH  1 
ATOM 4492 N N   . LEU D 1 119 ? -24.623 58.391  124.707 1.00 12.44  ? 119 LEU D N   1 
ATOM 4493 C CA  . LEU D 1 119 ? -23.879 58.906  125.850 1.00 12.44  ? 119 LEU D CA  1 
ATOM 4494 C C   . LEU D 1 119 ? -23.099 60.161  125.486 1.00 12.44  ? 119 LEU D C   1 
ATOM 4495 O O   . LEU D 1 119 ? -23.118 61.147  126.232 1.00 12.44  ? 119 LEU D O   1 
ATOM 4496 C CB  . LEU D 1 119 ? -22.931 57.833  126.388 1.00 12.44  ? 119 LEU D CB  1 
ATOM 4497 C CG  . LEU D 1 119 ? -23.576 56.647  127.107 1.00 12.44  ? 119 LEU D CG  1 
ATOM 4498 C CD1 . LEU D 1 119 ? -22.553 55.548  127.337 1.00 12.44  ? 119 LEU D CD1 1 
ATOM 4499 C CD2 . LEU D 1 119 ? -24.194 57.087  128.424 1.00 12.44  ? 119 LEU D CD2 1 
ATOM 4500 N N   . VAL D 1 120 ? -22.432 60.161  124.331 1.00 12.28  ? 120 VAL D N   1 
ATOM 4501 C CA  . VAL D 1 120 ? -21.725 61.363  123.886 1.00 12.28  ? 120 VAL D CA  1 
ATOM 4502 C C   . VAL D 1 120 ? -22.689 62.533  123.691 1.00 12.28  ? 120 VAL D C   1 
ATOM 4503 O O   . VAL D 1 120 ? -22.437 63.656  124.154 1.00 12.28  ? 120 VAL D O   1 
ATOM 4504 C CB  . VAL D 1 120 ? -20.929 61.069  122.601 1.00 12.28  ? 120 VAL D CB  1 
ATOM 4505 C CG1 . VAL D 1 120 ? -20.284 62.339  122.060 1.00 12.28  ? 120 VAL D CG1 1 
ATOM 4506 C CG2 . VAL D 1 120 ? -19.871 60.009  122.863 1.00 12.28  ? 120 VAL D CG2 1 
ATOM 4507 N N   . SER D 1 121 ? -23.803 62.296  122.994 1.00 12.37  ? 121 SER D N   1 
ATOM 4508 C CA  . SER D 1 121 ? -24.748 63.376  122.719 1.00 12.37  ? 121 SER D CA  1 
ATOM 4509 C C   . SER D 1 121 ? -25.362 63.941  123.996 1.00 12.37  ? 121 SER D C   1 
ATOM 4510 O O   . SER D 1 121 ? -25.486 65.163  124.148 1.00 12.37  ? 121 SER D O   1 
ATOM 4511 C CB  . SER D 1 121 ? -25.845 62.877  121.779 1.00 12.37  ? 121 SER D CB  1 
ATOM 4512 O OG  . SER D 1 121 ? -25.289 62.312  120.607 1.00 12.37  ? 121 SER D OG  1 
ATOM 4513 N N   . PHE D 1 122 ? -25.755 63.072  124.927 1.00 13.28  ? 122 PHE D N   1 
ATOM 4514 C CA  . PHE D 1 122 ? -26.284 63.537  126.204 1.00 13.28  ? 122 PHE D CA  1 
ATOM 4515 C C   . PHE D 1 122 ? -25.226 64.270  127.019 1.00 13.28  ? 122 PHE D C   1 
ATOM 4516 O O   . PHE D 1 122 ? -25.544 65.230  127.728 1.00 13.28  ? 122 PHE D O   1 
ATOM 4517 C CB  . PHE D 1 122 ? -26.847 62.354  126.993 1.00 13.28  ? 122 PHE D CB  1 
ATOM 4518 C CG  . PHE D 1 122 ? -27.664 62.756  128.187 1.00 13.28  ? 122 PHE D CG  1 
ATOM 4519 C CD1 . PHE D 1 122 ? -27.053 63.113  129.377 1.00 13.28  ? 122 PHE D CD1 1 
ATOM 4520 C CD2 . PHE D 1 122 ? -29.046 62.787  128.115 1.00 13.28  ? 122 PHE D CD2 1 
ATOM 4521 C CE1 . PHE D 1 122 ? -27.805 63.487  130.471 1.00 13.28  ? 122 PHE D CE1 1 
ATOM 4522 C CE2 . PHE D 1 122 ? -29.802 63.161  129.206 1.00 13.28  ? 122 PHE D CE2 1 
ATOM 4523 C CZ  . PHE D 1 122 ? -29.181 63.512  130.386 1.00 13.28  ? 122 PHE D CZ  1 
ATOM 4524 N N   . GLY D 1 123 ? -23.978 63.803  126.983 1.00 13.22  ? 123 GLY D N   1 
ATOM 4525 C CA  . GLY D 1 123 ? -22.910 64.550  127.627 1.00 13.22  ? 123 GLY D CA  1 
ATOM 4526 C C   . GLY D 1 123 ? -22.797 65.969  127.105 1.00 13.22  ? 123 GLY D C   1 
ATOM 4527 O O   . GLY D 1 123 ? -22.685 66.924  127.876 1.00 13.22  ? 123 GLY D O   1 
ATOM 4528 N N   . VAL D 1 124 ? -22.853 66.122  125.780 1.00 13.46  ? 124 VAL D N   1 
ATOM 4529 C CA  . VAL D 1 124 ? -22.845 67.457  125.179 1.00 13.46  ? 124 VAL D CA  1 
ATOM 4530 C C   . VAL D 1 124 ? -24.059 68.273  125.611 1.00 13.46  ? 124 VAL D C   1 
ATOM 4531 O O   . VAL D 1 124 ? -23.949 69.470  125.902 1.00 13.46  ? 124 VAL D O   1 
ATOM 4532 C CB  . VAL D 1 124 ? -22.764 67.346  123.645 1.00 13.46  ? 124 VAL D CB  1 
ATOM 4533 C CG1 . VAL D 1 124 ? -22.885 68.719  122.997 1.00 13.46  ? 124 VAL D CG1 1 
ATOM 4534 C CG2 . VAL D 1 124 ? -21.466 66.680  123.228 1.00 13.46  ? 124 VAL D CG2 1 
ATOM 4535 N N   . TRP D 1 125 ? -25.234 67.645  125.661 1.00 15.19  ? 125 TRP D N   1 
ATOM 4536 C CA  . TRP D 1 125 ? -26.445 68.363  126.059 1.00 15.19  ? 125 TRP D CA  1 
ATOM 4537 C C   . TRP D 1 125 ? -26.375 68.853  127.503 1.00 15.19  ? 125 TRP D C   1 
ATOM 4538 O O   . TRP D 1 125 ? -26.649 70.024  127.788 1.00 15.19  ? 125 TRP D O   1 
ATOM 4539 C CB  . TRP D 1 125 ? -27.668 67.466  125.854 1.00 15.19  ? 125 TRP D CB  1 
ATOM 4540 C CG  . TRP D 1 125 ? -28.970 68.129  126.195 1.00 15.19  ? 125 TRP D CG  1 
ATOM 4541 C CD1 . TRP D 1 125 ? -29.734 68.904  125.372 1.00 15.19  ? 125 TRP D CD1 1 
ATOM 4542 C CD2 . TRP D 1 125 ? -29.668 68.066  127.446 1.00 15.19  ? 125 TRP D CD2 1 
ATOM 4543 N NE1 . TRP D 1 125 ? -30.871 69.313  126.025 1.00 15.19  ? 125 TRP D NE1 1 
ATOM 4544 C CE2 . TRP D 1 125 ? -30.843 68.830  127.306 1.00 15.19  ? 125 TRP D CE2 1 
ATOM 4545 C CE3 . TRP D 1 125 ? -29.406 67.449  128.672 1.00 15.19  ? 125 TRP D CE3 1 
ATOM 4546 C CZ2 . TRP D 1 125 ? -31.758 68.989  128.345 1.00 15.19  ? 125 TRP D CZ2 1 
ATOM 4547 C CZ3 . TRP D 1 125 ? -30.317 67.605  129.700 1.00 15.19  ? 125 TRP D CZ3 1 
ATOM 4548 C CH2 . TRP D 1 125 ? -31.475 68.373  129.533 1.00 15.19  ? 125 TRP D CH2 1 
ATOM 4549 N N   . ILE D 1 126 ? -26.011 67.969  128.431 1.00 14.83  ? 126 ILE D N   1 
ATOM 4550 C CA  . ILE D 1 126 ? -25.980 68.324  129.849 1.00 14.83  ? 126 ILE D CA  1 
ATOM 4551 C C   . ILE D 1 126 ? -24.814 69.249  130.186 1.00 14.83  ? 126 ILE D C   1 
ATOM 4552 O O   . ILE D 1 126 ? -24.917 70.071  131.105 1.00 14.83  ? 126 ILE D O   1 
ATOM 4553 C CB  . ILE D 1 126 ? -25.956 67.048  130.711 1.00 14.83  ? 126 ILE D CB  1 
ATOM 4554 C CG1 . ILE D 1 126 ? -26.398 67.370  132.140 1.00 14.83  ? 126 ILE D CG1 1 
ATOM 4555 C CG2 . ILE D 1 126 ? -24.569 66.419  130.708 1.00 14.83  ? 126 ILE D CG2 1 
ATOM 4556 C CD1 . ILE D 1 126 ? -26.677 66.148  132.980 1.00 14.83  ? 126 ILE D CD1 1 
ATOM 4557 N N   . ARG D 1 127 ? -23.722 69.192  129.444 1.00 15.68  ? 127 ARG D N   1 
ATOM 4558 C CA  . ARG D 1 127 ? -22.619 70.150  129.674 1.00 15.68  ? 127 ARG D CA  1 
ATOM 4559 C C   . ARG D 1 127 ? -23.116 71.540  129.286 1.00 15.68  ? 127 ARG D C   1 
ATOM 4560 O O   . ARG D 1 127 ? -22.629 72.504  129.882 1.00 15.68  ? 127 ARG D O   1 
ATOM 4561 C CB  . ARG D 1 127 ? -21.366 69.769  128.888 1.00 15.68  ? 127 ARG D CB  1 
ATOM 4562 C CG  . ARG D 1 127 ? -20.523 68.702  129.565 1.00 15.68  ? 127 ARG D CG  1 
ATOM 4563 C CD  . ARG D 1 127 ? -19.212 68.482  128.845 1.00 15.68  ? 127 ARG D CD  1 
ATOM 4564 N NE  . ARG D 1 127 ? -19.422 67.972  127.500 1.00 15.68  ? 127 ARG D NE  1 
ATOM 4565 C CZ  . ARG D 1 127 ? -19.713 66.711  127.212 1.00 15.68  ? 127 ARG D CZ  1 
ATOM 4566 N NH1 . ARG D 1 127 ? -19.845 65.816  128.176 1.00 15.68  ? 127 ARG D NH1 1 
ATOM 4567 N NH2 . ARG D 1 127 ? -19.882 66.348  125.956 1.00 15.68  ? 127 ARG D NH2 1 
ATOM 4568 N N   . THR D 1 128 ? -24.050 71.659  128.334 1.00 19.41  ? 128 THR D N   1 
ATOM 4569 C CA  . THR D 1 128 ? -24.473 72.981  127.905 1.00 19.41  ? 128 THR D CA  1 
ATOM 4570 C C   . THR D 1 128 ? -25.153 73.714  129.061 1.00 19.41  ? 128 THR D C   1 
ATOM 4571 O O   . THR D 1 128 ? -25.978 73.128  129.769 1.00 19.41  ? 128 THR D O   1 
ATOM 4572 C CB  . THR D 1 128 ? -25.434 72.877  126.721 1.00 19.41  ? 128 THR D CB  1 
ATOM 4573 O OG1 . THR D 1 128 ? -24.748 72.326  125.590 1.00 19.41  ? 128 THR D OG1 1 
ATOM 4574 C CG2 . THR D 1 128 ? -25.985 74.247  126.354 1.00 19.41  ? 128 THR D CG2 1 
ATOM 4575 N N   . PRO D 1 129 ? -24.827 74.988  129.283 1.00 23.23  ? 129 PRO D N   1 
ATOM 4576 C CA  . PRO D 1 129 ? -25.508 75.740  130.332 1.00 23.23  ? 129 PRO D CA  1 
ATOM 4577 C C   . PRO D 1 129 ? -27.001 75.797  130.081 1.00 23.23  ? 129 PRO D C   1 
ATOM 4578 O O   . PRO D 1 129 ? -27.454 75.814  128.921 1.00 23.23  ? 129 PRO D O   1 
ATOM 4579 C CB  . PRO D 1 129 ? -24.867 77.132  130.238 1.00 23.23  ? 129 PRO D CB  1 
ATOM 4580 C CG  . PRO D 1 129 ? -23.514 76.873  129.705 1.00 23.23  ? 129 PRO D CG  1 
ATOM 4581 C CD  . PRO D 1 129 ? -23.689 75.745  128.728 1.00 23.23  ? 129 PRO D CD  1 
ATOM 4582 N N   . PRO D 1 130 ? -27.810 75.825  131.144 1.00 24.13  ? 130 PRO D N   1 
ATOM 4583 C CA  . PRO D 1 130 ? -29.269 75.761  130.955 1.00 24.13  ? 130 PRO D CA  1 
ATOM 4584 C C   . PRO D 1 130 ? -29.820 76.904  130.122 1.00 24.13  ? 130 PRO D C   1 
ATOM 4585 O O   . PRO D 1 130 ? -30.865 76.738  129.479 1.00 24.13  ? 130 PRO D O   1 
ATOM 4586 C CB  . PRO D 1 130 ? -29.813 75.799  132.391 1.00 24.13  ? 130 PRO D CB  1 
ATOM 4587 C CG  . PRO D 1 130 ? -28.699 76.346  133.221 1.00 24.13  ? 130 PRO D CG  1 
ATOM 4588 C CD  . PRO D 1 130 ? -27.441 75.886  132.568 1.00 24.13  ? 130 PRO D CD  1 
ATOM 4589 N N   . ALA D 1 131 ? -29.156 78.062  130.114 1.00 27.29  ? 131 ALA D N   1 
ATOM 4590 C CA  . ALA D 1 131 ? -29.655 79.190  129.338 1.00 27.29  ? 131 ALA D CA  1 
ATOM 4591 C C   . ALA D 1 131 ? -29.693 78.859  127.851 1.00 27.29  ? 131 ALA D C   1 
ATOM 4592 O O   . ALA D 1 131 ? -30.630 79.248  127.145 1.00 27.29  ? 131 ALA D O   1 
ATOM 4593 C CB  . ALA D 1 131 ? -28.789 80.424  129.591 1.00 27.29  ? 131 ALA D CB  1 
ATOM 4594 N N   . TYR D 1 132 ? -28.682 78.143  127.360 1.00 26.37  ? 132 TYR D N   1 
ATOM 4595 C CA  . TYR D 1 132 ? -28.571 77.808  125.948 1.00 26.37  ? 132 TYR D CA  1 
ATOM 4596 C C   . TYR D 1 132 ? -28.910 76.348  125.678 1.00 26.37  ? 132 TYR D C   1 
ATOM 4597 O O   . TYR D 1 132 ? -28.809 75.901  124.531 1.00 26.37  ? 132 TYR D O   1 
ATOM 4598 C CB  . TYR D 1 132 ? -27.151 78.103  125.450 1.00 26.37  ? 132 TYR D CB  1 
ATOM 4599 C CG  . TYR D 1 132 ? -26.648 79.479  125.820 1.00 26.37  ? 132 TYR D CG  1 
ATOM 4600 C CD1 . TYR D 1 132 ? -26.980 80.595  125.065 1.00 26.37  ? 132 TYR D CD1 1 
ATOM 4601 C CD2 . TYR D 1 132 ? -25.848 79.663  126.941 1.00 26.37  ? 132 TYR D CD2 1 
ATOM 4602 C CE1 . TYR D 1 132 ? -26.521 81.854  125.411 1.00 26.37  ? 132 TYR D CE1 1 
ATOM 4603 C CE2 . TYR D 1 132 ? -25.387 80.915  127.294 1.00 26.37  ? 132 TYR D CE2 1 
ATOM 4604 C CZ  . TYR D 1 132 ? -25.725 82.006  126.527 1.00 26.37  ? 132 TYR D CZ  1 
ATOM 4605 O OH  . TYR D 1 132 ? -25.265 83.255  126.881 1.00 26.37  ? 132 TYR D OH  1 
ATOM 4606 N N   . ARG D 1 133 ? -29.310 75.604  126.702 1.00 20.22  ? 133 ARG D N   1 
ATOM 4607 C CA  . ARG D 1 133 ? -29.654 74.197  126.534 1.00 20.22  ? 133 ARG D CA  1 
ATOM 4608 C C   . ARG D 1 133 ? -31.013 74.056  125.855 1.00 20.22  ? 133 ARG D C   1 
ATOM 4609 O O   . ARG D 1 133 ? -32.002 74.617  126.342 1.00 20.22  ? 133 ARG D O   1 
ATOM 4610 C CB  . ARG D 1 133 ? -29.676 73.510  127.897 1.00 20.22  ? 133 ARG D CB  1 
ATOM 4611 C CG  . ARG D 1 133 ? -29.545 72.003  127.849 1.00 20.22  ? 133 ARG D CG  1 
ATOM 4612 C CD  . ARG D 1 133 ? -29.590 71.422  129.251 1.00 20.22  ? 133 ARG D CD  1 
ATOM 4613 N NE  . ARG D 1 133 ? -28.413 71.785  130.029 1.00 20.22  ? 133 ARG D NE  1 
ATOM 4614 C CZ  . ARG D 1 133 ? -28.351 71.764  131.354 1.00 20.22  ? 133 ARG D CZ  1 
ATOM 4615 N NH1 . ARG D 1 133 ? -29.390 71.405  132.090 1.00 20.22  ? 133 ARG D NH1 1 
ATOM 4616 N NH2 . ARG D 1 133 ? -27.218 72.112  131.955 1.00 20.22  ? 133 ARG D NH2 1 
ATOM 4617 N N   . PRO D 1 134 ? -31.114 73.326  124.739 1.00 19.13  ? 134 PRO D N   1 
ATOM 4618 C CA  . PRO D 1 134 ? -32.417 73.159  124.103 1.00 19.13  ? 134 PRO D CA  1 
ATOM 4619 C C   . PRO D 1 134 ? -33.338 72.329  124.978 1.00 19.13  ? 134 PRO D C   1 
ATOM 4620 O O   . PRO D 1 134 ? -32.874 71.516  125.796 1.00 19.13  ? 134 PRO D O   1 
ATOM 4621 C CB  . PRO D 1 134 ? -32.081 72.435  122.787 1.00 19.13  ? 134 PRO D CB  1 
ATOM 4622 C CG  . PRO D 1 134 ? -30.801 71.745  123.053 1.00 19.13  ? 134 PRO D CG  1 
ATOM 4623 C CD  . PRO D 1 134 ? -30.047 72.631  123.996 1.00 19.13  ? 134 PRO D CD  1 
ATOM 4624 N N   . PRO D 1 135 ? -34.656 72.497  124.845 1.00 20.31  ? 135 PRO D N   1 
ATOM 4625 C CA  . PRO D 1 135 ? -35.571 71.785  125.751 1.00 20.31  ? 135 PRO D CA  1 
ATOM 4626 C C   . PRO D 1 135 ? -35.635 70.288  125.504 1.00 20.31  ? 135 PRO D C   1 
ATOM 4627 O O   . PRO D 1 135 ? -35.791 69.522  126.463 1.00 20.31  ? 135 PRO D O   1 
ATOM 4628 C CB  . PRO D 1 135 ? -36.923 72.457  125.475 1.00 20.31  ? 135 PRO D CB  1 
ATOM 4629 C CG  . PRO D 1 135 ? -36.813 72.927  124.066 1.00 20.31  ? 135 PRO D CG  1 
ATOM 4630 C CD  . PRO D 1 135 ? -35.383 73.365  123.905 1.00 20.31  ? 135 PRO D CD  1 
ATOM 4631 N N   . ASN D 1 136 ? -35.520 69.848  124.254 1.00 20.72  ? 136 ASN D N   1 
ATOM 4632 C CA  . ASN D 1 136 ? -35.637 68.432  123.907 1.00 20.72  ? 136 ASN D CA  1 
ATOM 4633 C C   . ASN D 1 136 ? -34.300 67.738  124.131 1.00 20.72  ? 136 ASN D C   1 
ATOM 4634 O O   . ASN D 1 136 ? -33.375 67.866  123.328 1.00 20.72  ? 136 ASN D O   1 
ATOM 4635 C CB  . ASN D 1 136 ? -36.099 68.274  122.464 1.00 20.72  ? 136 ASN D CB  1 
ATOM 4636 C CG  . ASN D 1 136 ? -37.505 68.793  122.241 1.00 20.72  ? 136 ASN D CG  1 
ATOM 4637 O OD1 . ASN D 1 136 ? -38.123 69.353  123.146 1.00 20.72  ? 136 ASN D OD1 1 
ATOM 4638 N ND2 . ASN D 1 136 ? -38.020 68.605  121.032 1.00 20.72  ? 136 ASN D ND2 1 
ATOM 4639 N N   . ALA D 1 137 ? -34.198 66.997  125.231 1.00 15.50  ? 137 ALA D N   1 
ATOM 4640 C CA  . ALA D 1 137 ? -32.970 66.289  125.543 1.00 15.50  ? 137 ALA D CA  1 
ATOM 4641 C C   . ALA D 1 137 ? -32.866 65.031  124.683 1.00 15.50  ? 137 ALA D C   1 
ATOM 4642 O O   . ALA D 1 137 ? -33.884 64.487  124.247 1.00 15.50  ? 137 ALA D O   1 
ATOM 4643 C CB  . ALA D 1 137 ? -32.929 65.910  127.018 1.00 15.50  ? 137 ALA D CB  1 
ATOM 4644 N N   . PRO D 1 138 ? -31.653 64.547  124.417 1.00 13.67  ? 138 PRO D N   1 
ATOM 4645 C CA  . PRO D 1 138 ? -31.525 63.299  123.657 1.00 13.67  ? 138 PRO D CA  1 
ATOM 4646 C C   . PRO D 1 138 ? -32.191 62.140  124.380 1.00 13.67  ? 138 PRO D C   1 
ATOM 4647 O O   . PRO D 1 138 ? -32.161 62.048  125.608 1.00 13.67  ? 138 PRO D O   1 
ATOM 4648 C CB  . PRO D 1 138 ? -30.009 63.104  123.550 1.00 13.67  ? 138 PRO D CB  1 
ATOM 4649 C CG  . PRO D 1 138 ? -29.433 64.460  123.746 1.00 13.67  ? 138 PRO D CG  1 
ATOM 4650 C CD  . PRO D 1 138 ? -30.338 65.133  124.727 1.00 13.67  ? 138 PRO D CD  1 
ATOM 4651 N N   . ILE D 1 139 ? -32.798 61.248  123.599 1.00 13.26  ? 139 ILE D N   1 
ATOM 4652 C CA  . ILE D 1 139 ? -33.482 60.080  124.137 1.00 13.26  ? 139 ILE D CA  1 
ATOM 4653 C C   . ILE D 1 139 ? -33.299 58.932  123.160 1.00 13.26  ? 139 ILE D C   1 
ATOM 4654 O O   . ILE D 1 139 ? -33.220 59.133  121.944 1.00 13.26  ? 139 ILE D O   1 
ATOM 4655 C CB  . ILE D 1 139 ? -34.981 60.367  124.397 1.00 13.26  ? 139 ILE D CB  1 
ATOM 4656 C CG1 . ILE D 1 139 ? -35.636 59.175  125.100 1.00 13.26  ? 139 ILE D CG1 1 
ATOM 4657 C CG2 . ILE D 1 139 ? -35.701 60.689  123.094 1.00 13.26  ? 139 ILE D CG2 1 
ATOM 4658 C CD1 . ILE D 1 139 ? -37.002 59.477  125.672 1.00 13.26  ? 139 ILE D CD1 1 
ATOM 4659 N N   . LEU D 1 140 ? -33.224 57.716  123.696 1.00 13.29  ? 140 LEU D N   1 
ATOM 4660 C CA  . LEU D 1 140 ? -33.090 56.517  122.881 1.00 13.29  ? 140 LEU D CA  1 
ATOM 4661 C C   . LEU D 1 140 ? -34.468 56.030  122.453 1.00 13.29  ? 140 LEU D C   1 
ATOM 4662 O O   . LEU D 1 140 ? -35.341 55.799  123.296 1.00 13.29  ? 140 LEU D O   1 
ATOM 4663 C CB  . LEU D 1 140 ? -32.361 55.421  123.657 1.00 13.29  ? 140 LEU D CB  1 
ATOM 4664 C CG  . LEU D 1 140 ? -30.852 55.589  123.829 1.00 13.29  ? 140 LEU D CG  1 
ATOM 4665 C CD1 . LEU D 1 140 ? -30.360 54.768  125.007 1.00 13.29  ? 140 LEU D CD1 1 
ATOM 4666 C CD2 . LEU D 1 140 ? -30.125 55.190  122.557 1.00 13.29  ? 140 LEU D CD2 1 
ATOM 4667 N N   . SER D 1 141 ? -34.664 55.882  121.146 1.00 21.34  ? 141 SER D N   1 
ATOM 4668 C CA  . SER D 1 141 ? -35.935 55.415  120.613 1.00 21.34  ? 141 SER D CA  1 
ATOM 4669 C C   . SER D 1 141 ? -35.698 54.882  119.208 1.00 21.34  ? 141 SER D C   1 
ATOM 4670 O O   . SER D 1 141 ? -34.695 55.199  118.566 1.00 21.34  ? 141 SER D O   1 
ATOM 4671 C CB  . SER D 1 141 ? -36.987 56.528  120.598 1.00 21.34  ? 141 SER D CB  1 
ATOM 4672 O OG  . SER D 1 141 ? -36.627 57.559  119.695 1.00 21.34  ? 141 SER D OG  1 
ATOM 4673 N N   . THR D 1 142 ? -36.642 54.068  118.739 1.00 29.75  ? 142 THR D N   1 
ATOM 4674 C CA  . THR D 1 142 ? -36.622 53.573  117.368 1.00 29.75  ? 142 THR D CA  1 
ATOM 4675 C C   . THR D 1 142 ? -37.498 54.392  116.434 1.00 29.75  ? 142 THR D C   1 
ATOM 4676 O O   . THR D 1 142 ? -37.099 54.669  115.298 1.00 29.75  ? 142 THR D O   1 
ATOM 4677 C CB  . THR D 1 142 ? -37.081 52.112  117.325 1.00 29.75  ? 142 THR D CB  1 
ATOM 4678 O OG1 . THR D 1 142 ? -38.418 52.012  117.833 1.00 29.75  ? 142 THR D OG1 1 
ATOM 4679 C CG2 . THR D 1 142 ? -36.161 51.234  118.156 1.00 29.75  ? 142 THR D CG2 1 
ATOM 4680 N N   . LEU D 1 143 ? -38.679 54.784  116.888 1.00 42.88  ? 143 LEU D N   1 
ATOM 4681 C CA  . LEU D 1 143 ? -39.670 55.449  116.060 1.00 42.88  ? 143 LEU D CA  1 
ATOM 4682 C C   . LEU D 1 143 ? -39.585 56.967  116.183 1.00 42.88  ? 143 LEU D C   1 
ATOM 4683 O O   . LEU D 1 143 ? -39.014 57.496  117.141 1.00 42.88  ? 143 LEU D O   1 
ATOM 4684 C CB  . LEU D 1 143 ? -41.060 54.933  116.438 1.00 42.88  ? 143 LEU D CB  1 
ATOM 4685 C CG  . LEU D 1 143 ? -41.549 55.147  117.878 1.00 42.88  ? 143 LEU D CG  1 
ATOM 4686 C CD1 . LEU D 1 143 ? -42.151 56.508  118.126 1.00 42.88  ? 143 LEU D CD1 1 
ATOM 4687 C CD2 . LEU D 1 143 ? -42.544 54.055  118.244 1.00 42.88  ? 143 LEU D CD2 1 
ATOM 4688 N N   . PRO D 1 144 ? -40.142 57.700  115.217 1.00 50.67  ? 144 PRO D N   1 
ATOM 4689 C CA  . PRO D 1 144 ? -40.210 59.162  115.334 1.00 50.67  ? 144 PRO D CA  1 
ATOM 4690 C C   . PRO D 1 144 ? -41.211 59.587  116.394 1.00 50.67  ? 144 PRO D C   1 
ATOM 4691 O O   . PRO D 1 144 ? -42.137 58.853  116.735 1.00 50.67  ? 144 PRO D O   1 
ATOM 4692 C CB  . PRO D 1 144 ? -40.660 59.616  113.940 1.00 50.67  ? 144 PRO D CB  1 
ATOM 4693 C CG  . PRO D 1 144 ? -40.374 58.459  113.042 1.00 50.67  ? 144 PRO D CG  1 
ATOM 4694 C CD  . PRO D 1 144 ? -40.584 57.247  113.889 1.00 50.67  ? 144 PRO D CD  1 
ATOM 4695 N N   . GLU D 1 145 ? -41.056 60.825  116.872 1.00 55.52  ? 145 GLU D N   1 
ATOM 4696 C CA  . GLU D 1 145 ? -41.941 61.301  117.932 1.00 55.52  ? 145 GLU D CA  1 
ATOM 4697 C C   . GLU D 1 145 ? -43.401 61.096  117.549 1.00 55.52  ? 145 GLU D C   1 
ATOM 4698 O O   . GLU D 1 145 ? -44.192 60.562  118.334 1.00 55.52  ? 145 GLU D O   1 
ATOM 4699 C CB  . GLU D 1 145 ? -41.659 62.778  118.221 1.00 55.52  ? 145 GLU D CB  1 
ATOM 4700 C CG  . GLU D 1 145 ? -40.295 63.040  118.831 1.00 55.52  ? 145 GLU D CG  1 
ATOM 4701 C CD  . GLU D 1 145 ? -40.021 64.517  119.036 1.00 55.52  ? 145 GLU D CD  1 
ATOM 4702 O OE1 . GLU D 1 145 ? -40.808 65.346  118.532 1.00 55.52  ? 145 GLU D OE1 1 
ATOM 4703 O OE2 . GLU D 1 145 ? -39.016 64.848  119.700 1.00 55.52  ? 145 GLU D OE2 1 
ATOM 4704 N N   . THR D 1 146 ? -43.776 61.510  116.342 1.00 59.25  ? 146 THR D N   1 
ATOM 4705 C CA  . THR D 1 146 ? -45.117 61.308  115.810 1.00 59.25  ? 146 THR D CA  1 
ATOM 4706 C C   . THR D 1 146 ? -45.023 60.286  114.684 1.00 59.25  ? 146 THR D C   1 
ATOM 4707 O O   . THR D 1 146 ? -44.310 60.513  113.702 1.00 59.25  ? 146 THR D O   1 
ATOM 4708 C CB  . THR D 1 146 ? -45.718 62.618  115.298 1.00 59.25  ? 146 THR D CB  1 
ATOM 4709 O OG1 . THR D 1 146 ? -44.881 63.163  114.271 1.00 59.25  ? 146 THR D OG1 1 
ATOM 4710 C CG2 . THR D 1 146 ? -45.854 63.624  116.428 1.00 59.25  ? 146 THR D CG2 1 
ATOM 4711 N N   . THR D 1 147 ? -45.736 59.171  114.818 1.00 63.93  ? 147 THR D N   1 
ATOM 4712 C CA  . THR D 1 147 ? -45.641 58.094  113.842 1.00 63.93  ? 147 THR D CA  1 
ATOM 4713 C C   . THR D 1 147 ? -46.845 58.128  112.907 1.00 63.93  ? 147 THR D C   1 
ATOM 4714 O O   . THR D 1 147 ? -47.987 58.283  113.351 1.00 63.93  ? 147 THR D O   1 
ATOM 4715 C CB  . THR D 1 147 ? -45.558 56.733  114.535 1.00 63.93  ? 147 THR D CB  1 
ATOM 4716 O OG1 . THR D 1 147 ? -44.557 56.778  115.560 1.00 63.93  ? 147 THR D OG1 1 
ATOM 4717 C CG2 . THR D 1 147 ? -45.202 55.641  113.536 1.00 63.93  ? 147 THR D CG2 1 
ATOM 4718 N N   . VAL D 1 148 ? -46.578 57.977  111.614 1.00 75.60  ? 148 VAL D N   1 
ATOM 4719 C CA  . VAL D 1 148 ? -47.606 57.962  110.580 1.00 75.60  ? 148 VAL D CA  1 
ATOM 4720 C C   . VAL D 1 148 ? -47.820 56.520  110.140 1.00 75.60  ? 148 VAL D C   1 
ATOM 4721 O O   . VAL D 1 148 ? -46.891 55.877  109.636 1.00 75.60  ? 148 VAL D O   1 
ATOM 4722 C CB  . VAL D 1 148 ? -47.222 58.852  109.388 1.00 75.60  ? 148 VAL D CB  1 
ATOM 4723 C CG1 . VAL D 1 148 ? -48.290 58.782  108.308 1.00 75.60  ? 148 VAL D CG1 1 
ATOM 4724 C CG2 . VAL D 1 148 ? -47.015 60.291  109.844 1.00 75.60  ? 148 VAL D CG2 1 
ATOM 4725 N N   . VAL D 1 149 ? -49.032 56.003  110.325 1.00 81.06  ? 149 VAL D N   1 
ATOM 4726 C CA  . VAL D 1 149 ? -49.374 54.664  109.862 1.00 81.06  ? 149 VAL D CA  1 
ATOM 4727 C C   . VAL D 1 149 ? -50.763 54.700  109.245 1.00 81.06  ? 149 VAL D C   1 
ATOM 4728 O O   . VAL D 1 149 ? -51.682 55.322  109.787 1.00 81.06  ? 149 VAL D O   1 
ATOM 4729 C CB  . VAL D 1 149 ? -49.310 53.628  111.006 1.00 81.06  ? 149 VAL D CB  1 
ATOM 4730 C CG1 . VAL D 1 149 ? -49.529 52.222  110.461 1.00 81.06  ? 149 VAL D CG1 1 
ATOM 4731 C CG2 . VAL D 1 149 ? -47.980 53.718  111.737 1.00 81.06  ? 149 VAL D CG2 1 
ATOM 4732 N N   . ARG D 1 150 ? -50.910 54.030  108.103 1.00 93.10  ? 150 ARG D N   1 
ATOM 4733 C CA  . ARG D 1 150 ? -52.201 53.794  107.476 1.00 93.10  ? 150 ARG D CA  1 
ATOM 4734 C C   . ARG D 1 150 ? -52.191 52.394  106.884 1.00 93.10  ? 150 ARG D C   1 
ATOM 4735 O O   . ARG D 1 150 ? -51.157 51.932  106.393 1.00 93.10  ? 150 ARG D O   1 
ATOM 4736 C CB  . ARG D 1 150 ? -52.507 54.843  106.399 1.00 93.10  ? 150 ARG D CB  1 
ATOM 4737 C CG  . ARG D 1 150 ? -53.871 54.684  105.747 1.00 93.10  ? 150 ARG D CG  1 
ATOM 4738 C CD  . ARG D 1 150 ? -54.177 55.841  104.807 1.00 93.10  ? 150 ARG D CD  1 
ATOM 4739 N NE  . ARG D 1 150 ? -53.244 55.913  103.689 1.00 93.10  ? 150 ARG D NE  1 
ATOM 4740 C CZ  . ARG D 1 150 ? -53.369 55.234  102.558 1.00 93.10  ? 150 ARG D CZ  1 
ATOM 4741 N NH1 . ARG D 1 150 ? -54.375 54.398  102.358 1.00 93.10  ? 150 ARG D NH1 1 
ATOM 4742 N NH2 . ARG D 1 150 ? -52.463 55.398  101.598 1.00 93.10  ? 150 ARG D NH2 1 
ATOM 4743 N N   . ARG D 1 151 ? -53.339 51.723  106.926 1.00 95.89  ? 151 ARG D N   1 
ATOM 4744 C CA  . ARG D 1 151 ? -53.453 50.340  106.488 1.00 95.89  ? 151 ARG D CA  1 
ATOM 4745 C C   . ARG D 1 151 ? -54.503 50.222  105.391 1.00 95.89  ? 151 ARG D C   1 
ATOM 4746 O O   . ARG D 1 151 ? -55.524 50.914  105.417 1.00 95.89  ? 151 ARG D O   1 
ATOM 4747 C CB  . ARG D 1 151 ? -53.810 49.421  107.660 1.00 95.89  ? 151 ARG D CB  1 
ATOM 4748 C CG  . ARG D 1 151 ? -52.755 49.399  108.755 1.00 95.89  ? 151 ARG D CG  1 
ATOM 4749 C CD  . ARG D 1 151 ? -53.077 48.379  109.833 1.00 95.89  ? 151 ARG D CD  1 
ATOM 4750 N NE  . ARG D 1 151 ? -52.927 47.009  109.355 1.00 95.89  ? 151 ARG D NE  1 
ATOM 4751 C CZ  . ARG D 1 151 ? -51.766 46.378  109.237 1.00 95.89  ? 151 ARG D CZ  1 
ATOM 4752 N NH1 . ARG D 1 151 ? -50.619 46.986  109.496 1.00 95.89  ? 151 ARG D NH1 1 
ATOM 4753 N NH2 . ARG D 1 151 ? -51.755 45.111  108.833 1.00 95.89  ? 151 ARG D NH2 1 
ATOM 4754 N N   . ARG D 1 152 ? -54.237 49.340  104.428 1.00 99.83  ? 152 ARG D N   1 
ATOM 4755 C CA  . ARG D 1 152 ? -55.066 49.207  103.240 1.00 99.83  ? 152 ARG D CA  1 
ATOM 4756 C C   . ARG D 1 152 ? -55.004 47.767  102.752 1.00 99.83  ? 152 ARG D C   1 
ATOM 4757 O O   . ARG D 1 152 ? -54.015 47.064  102.973 1.00 99.83  ? 152 ARG D O   1 
ATOM 4758 C CB  . ARG D 1 152 ? -54.613 50.159  102.128 1.00 99.83  ? 152 ARG D CB  1 
ATOM 4759 C CG  . ARG D 1 152 ? -55.549 50.207  100.931 1.00 99.83  ? 152 ARG D CG  1 
ATOM 4760 C CD  . ARG D 1 152 ? -55.119 51.269  99.930  1.00 99.83  ? 152 ARG D CD  1 
ATOM 4761 N NE  . ARG D 1 152 ? -56.006 51.324  98.774  1.00 99.83  ? 152 ARG D NE  1 
ATOM 4762 C CZ  . ARG D 1 152 ? -55.853 50.604  97.671  1.00 99.83  ? 152 ARG D CZ  1 
ATOM 4763 N NH1 . ARG D 1 152 ? -54.864 49.735  97.542  1.00 99.83  ? 152 ARG D NH1 1 
ATOM 4764 N NH2 . ARG D 1 152 ? -56.719 50.755  96.673  1.00 99.83  ? 152 ARG D NH2 1 
ATOM 4765 N N   . GLY D 1 153 ? -56.070 47.341  102.084 1.00 100.87 ? 153 GLY D N   1 
ATOM 4766 C CA  . GLY D 1 153 ? -56.128 46.010  101.507 1.00 100.87 ? 153 GLY D CA  1 
ATOM 4767 C C   . GLY D 1 153 ? -57.449 45.726  100.819 1.00 100.87 ? 153 GLY D C   1 
ATOM 4768 O O   . GLY D 1 153 ? -58.443 46.412  101.058 1.00 100.87 ? 153 GLY D O   1 
# 
